pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Efficacy and Safety of the Concomitant of RUTI® Immunotherapy With the Standard Treatment in TB Patients
Status: WITHDRAWN
Conditions: Tuberculosis
Interventions: BIOLOGICAL: RUTI® vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Preserved Mitral Valve Apparatus During Mitral Valve Replacement
Status: COMPLETED
Conditions: Diseases of Mitral Valves|Abnormality of Mitral Valve Annulus (Disorder)|Mitral Valve Replacement
Interventions: DEVICE: St.Jude bi leaflet prosthetic mitral valve to replace the diseased valve with preservation of both leaflets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: iodine I 131 monoclonal antibody CC49-deltaCH2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerance and Effects on the Intestinal Flora of a New Fermented Milk for Preterm Infants
Status: COMPLETED
Conditions: Preterms With Gestational Age Ranging From 30 to 35 Weeks
Interventions: DIETARY_SUPPLEMENT: Milk with probiotic and prebiotic activities|DIETARY_SUPPLEMENT: Milk without probiotic and prebiotic activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cancer Screening Program for Women at High Risk for Developing Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Diseases|Ovarian Neoplasms
Interventions: OTHER: Laboratory Tumor Marker Analysis|OTHER: Transvaginal Ultrasound|OTHER: Health Status Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feedback in Augmented Reality to Control of Gait Parameters in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Gait Disorders, Neurologic|Feedback, Psychological
Interventions: DEVICE: Feedback modalities given through an augmented reality headset
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Ultrafast Hypothermia Before Reperfusion in STEMI Patients
Status: TERMINATED
Conditions: ST-elevation MI|Hypothermia
Interventions: DEVICE: Velomedix APLS device|OTHER: No Hypothermia Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Planning Based on Positron Emission Tomography With Fluoro-deoxyglucose For Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: restriction of radiotherapy to FDG-PET positive areas only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioneuroablation for Bradyarrhythmia
Status: RECRUITING
Conditions: Bradycardia|Syncope|Sick Sinus Syndrome
Interventions: PROCEDURE: Ganglionated plexi ablation|DIAGNOSTIC_TEST: Electrophysiological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract
Status: TERMINATED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Multiple Dose of PK/PD Study of SHR2285 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Thrombus
Interventions: DRUG: SHR2285 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CHIZAP: Community- and Health Facility-Based Intervention With Zinc as Adjuvant Therapy for Childhood Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KSH01-TCRT Solid Tumors
Status: RECRUITING
Conditions: TCR-T Cells|Refractory Solid Tumors|Relapsed Solid Tumors
Interventions: DRUG: KSH01 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Evaluation of the Saint Francis Ministries Fatherhood FIRE Program
Status: ENROLLING_BY_INVITATION
Conditions: Parenting|Parent-Child Relations|Relationship, Marital|Relationship, Family|Relationships, Father-Child|Fathers
Interventions: BEHAVIORAL: Enhanced Saint Francis Fatherhood FIRE Program|BEHAVIORAL: Services as Usual Saint Francis Fatherhood FIRE Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the VasoNova VPS System During PICC Placement in an Algorithm Confirmation Study Using Fluoroscopy
Status: COMPLETED
Conditions: Any Condition Requiring a PICC Placement
Interventions: DEVICE: VPS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biologically Modified Saphenous Vein Transplants for Improved CABG Outcomes
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: DRUG: Polyarginine|DRUG: Vein soak treated with Lactated Ringers Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study of NNZ-2566 in Patients With Rett Syndrome
Status: COMPLETED
Conditions: Rett Syndrome
Interventions: DRUG: NNZ-2566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Vitamin D Supplementation
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D (cholecalciferol)|DIETARY_SUPPLEMENT: Glucosamine sulfate and omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of the Dentist in the Control of the Alcoholic Habit in Patients With Potentially Malignant Oral Lesions
Status: RECRUITING
Conditions: Oral Potentially Malignant Disorders|Alcohol Drinking
Interventions: BEHAVIORAL: Brief intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of a Multidisciplinary Program for the Treatment of Chronic Pelvic Pain
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pelvic Pain Syndrome
Interventions: BEHAVIORAL: Chronic Pelvic Pain Treatment Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histopathological Analysis of Temporal Artery Biopsy Following Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings in Patients With Suspected Giant Cell Arteritis (DOCTA)
Status: COMPLETED
Conditions: Giant Cell Arteritis|Tomography, Optical Coherence
Interventions: OTHER: Dynamic full-field optical coherence tomography analysis of temporal artery biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Food Intake Decisions
Status: TERMINATED
Conditions: Healthy
Interventions: OTHER: Odors|OTHER: Visual stimulation|OTHER: Experimental Task|OTHER: Blood tests|OTHER: Questionnaires and test administered|OTHER: fMRI|OTHER: Odors 2|OTHER: Images|OTHER: Experimental Task fMRI|OTHER: Genotyping for susceptibility to β-ionone|OTHER: Experimental Task 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ERAS Protocol in Newborns: CARES Study
Status: NOT_YET_RECRUITING
Conditions: Pediatric
Interventions: DIETARY_SUPPLEMENT: feeding with breastmilk within 48 hours after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of E-Cigarette Flavors on Adults TCORS 2.0
Status: COMPLETED
Conditions: Nicotine Use Disorder
Interventions: DRUG: Nicotine|DRUG: Flavor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: EDCR Study - Etanercept Diamyd Combination Regimen -Open Trial to Evaluate Safety in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: GAD-Alum|DRUG: Vitamin D|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of A Controlled Release Formulation Of Pregabalin In Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Status: COMPLETED
Conditions: Depressive Disorder, Major|Bipolar Disorder|Post Traumatic Stress Disorder
Interventions: DRUG: Ketamine|DRUG: Perampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Muscular and Metabolic Adaptations to Exercise to Benefit High-Risk Workforce
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: PROCEDURE: Exercise 1|PROCEDURE: Exercise 2|PROCEDURE: Exercise 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SPECT-CT Metabolic/Morphological Assessment of Cemented Hip Protheses
Status: RECRUITING
Conditions: Arthropathy of Hip
Interventions: DEVICE: Total hip arthroplasty using the Exeter V40 cemented femoral stem|DEVICE: Total hip arthroplasty using the Müller Straight Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The E-health Application To Modify ORal Energy Intake and Measure Outcomes REmotely in ALS Clinical Trial (EAT MORE2)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: ALS Nutrition App (MyDataHelps platform)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)
Status: COMPLETED
Conditions: Anxiety Disorders|Mental Health
Interventions: DRUG: Hypericum perforatum (St. John's wort)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Multi-Energy Digital Radiography Detector for Lung Lesions Detection
Status: UNKNOWN
Conditions: Lung Tumor|Solitary Pulmonary Nodule
Interventions: DEVICE: Multi-Energy Digital Radiography Detector System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of PRGF Supplementation After TMJ Arthrocentesis in Patients With TMJ Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: TMJ|Osteoarthritis
Interventions: BIOLOGICAL: Plasma Rich in Growth Factor (PRGF) Supplementation|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expanding Fertility Care to Poor and Low Resourced Settings Study
Status: RECRUITING
Conditions: Healthy|Male Infertility|Infertility, Male|Fertility Disorders
Interventions: OTHER: Mail-in semen analysis kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Ramucirumab (LY3009806) Versus Placebo in Participants With Hepatocellular Carcinoma and Elevated Baseline Alpha-Fetoprotein
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Ramucirumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The UnProcessed Pantry Project (UP3)
Status: COMPLETED
Conditions: Diet, Healthy|Diet Habit|Disease, Chronic|Health Behavior|Rural Health
Interventions: BEHAVIORAL: The UnProcessed Pantry Project (UP3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Ketamine on Eye Movements, Perception and Brain Function
Status: COMPLETED
Conditions: Functional Neuroimaging
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy Following Surgery in Treating Patients With Advanced Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: MEBO Wound Ointment (MEBO)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Spastic Cerebral Palsy
Interventions: BEHAVIORAL: Spinal reflex conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Effectiveness of CAM Treatments for Lumbar and Cervical Spine Pain Patients Due to Spinal Disease
Status: COMPLETED
Conditions: Lumbar and Cervical Pain
Interventions: DRUG: herbal medicine|PROCEDURE: Chuna manual therapy|PROCEDURE: Acupuncture|PROCEDURE: Bee-venom pharmacoacupuncture/pharmacoacupuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV Subjects
Status: TERMINATED
Conditions: HIV-1
Interventions: DRUG: fosamprenavir/ritonavir (700mg/100mg BID)|DRUG: fosamprenavir/ritonavir (1400mg/100mg BID)|DRUG: fosamprenavir/lopinavir/ritonavir (1400mg/533mg/100mg BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarket Study of an Intraocular Lens Power Selection System
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ORA with VerifEye+|OTHER: Alcon Barrett Toric Calculator|DEVICE: Acrysof® IQ Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma
Status: NOT_YET_RECRUITING
Conditions: Neoplasms|High Grade Glioma|Glioblastoma Multiforme|Malignant Glioma of Brain|Anaplastic Astrocytoma of Brain|High-grade Glioma|Anaplastic Glioma|Giant Cell Glioblastoma
Interventions: DRUG: Biological G207
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of HE3286 in Patients With Active, Mild-to-Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Placebo|DRUG: HE3286
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
Status: RECRUITING
Conditions: Hairy Cell Leukemia (HCL)|Chronic Lymphocytic Leukemia (CLL)|Non-Hodgkins Lymphoma (NHL)|Cutaneous T Cell Lymphoma (CTCL)|Adult T Cell Lymphoma (ATL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study In Japanese Subjects With Type 2 Diabetes Mellitus As Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PF-04937319 high dose|DRUG: PF-04937319 low dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Oral Single Dose of TAK-418 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: TAK-418|DRUG: TAK-418 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Long-term Transcranial Direct Current Stimulation (tDCS) on Appetite Control Related Brain Regions
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: real tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2-Site Safety Study of Besivance Versus Vigamox Prophylactically in Routine Cataract Surgery
Status: COMPLETED
Conditions: Corneal Health|Cataract Surgery
Interventions: DRUG: besivance|DRUG: vigamox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: IDP-108|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery
Status: UNKNOWN
Conditions: High Risk Non-cardiac Surgery|Death|Delirium|Kidney Injury|Myocardial Infarction|Respiratory Failure|Postoperative Infection
Interventions: OTHER: Observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of a Transitional Care Program on 30-Day Hospital Readmissions for Elderly Patients Discharged From a Short Stay Geriatric Ward
Status: COMPLETED
Conditions: Geriatrics
Interventions: OTHER: Transitional care program.|OTHER: standard care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Effect of Compassion-Based Education Program Applied to Mothers of Children Diagnosed With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Compassion-Based Education Program Adapted for Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy
Status: TERMINATED
Conditions: Depression
Interventions: OTHER: Deprexis|DEVICE: Active low-level light therapy|DEVICE: Sham low-level light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis
Status: TERMINATED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Sirukumab|DRUG: Placebo to match sirukumab|DRUG: Prednisone|DRUG: Placebo to match prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Active (Pramipexole 0.5 mg Tid) and Placebo Controlled, Study of Pramipexole Given 0.5 mg and 0.75 mg Bid Over 12-week Treatment in Early Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Opioids for Colorectal Resection
Status: COMPLETED
Conditions: Colorectal Surgery|Pain, Postoperative|Analgesic, Opioid
Interventions: DRUG: Morphine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Action Mechanisms of Shock Waves on Pain
Status: COMPLETED
Conditions: Asymptomatic Condition
Interventions: OTHER: Sham Comparator|OTHER: Experimental Intervention|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the 755nm Alexandrite for the Treatment of Epidermal and Dermal Pigmented Lesions
Status: COMPLETED
Conditions: Dermal and Epidermal Pigmented Lesions
Interventions: DEVICE: 755nm Alexandrite Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Efficacy of Ultrasound-guided Ozone Injection in the Treatment of Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain, Posterior Compartment
Interventions: PROCEDURE: deep paravertebral periforaminal ozone injeciton|PROCEDURE: transforaminal steroid injeciton
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tyrosine Kinase Inhibitors on Liver Enzymes and Electrolytes
Status: UNKNOWN
Conditions: Patients Diagnosed as Chronic Meyloid Leukemia
Interventions: DRUG: Tyrosine kinase Inhibitors (Imatinib & Nilotinib)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Symptom Management Program Based on Story Theory for Postmenopausal Women (SEMSTOP)
Status: NOT_YET_RECRUITING
Conditions: Menopause
Interventions: OTHER: SEMSTOP|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors
Status: COMPLETED
Conditions: Diabetic Nephropathy|Chronic Kidney Disease
Interventions: DRUG: Zemplar (paricalcitol ) capsules|DRUG: Zemplar (paricalcitol) capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety,Pharmacokinetics and Efficacy of CAZ-AVI With Metronidazole in Children Aged 3 Months to 18 Years Old With Complicated Intra-abdominal Infections (cIAIs).
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infections
Interventions: DRUG: Ceftazidime -avibactam|DRUG: Meropenem|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage|Acute Stroke
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Sham remote ischemic conditioning|DRUG: Standard medication therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, and Pharmacokinetics of Once Weekly Zicronapine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Zicronapine open-label lead-in 10 mg daily|DRUG: Zicronapine 10 mg daily|DRUG: Zicronapine 20 mg once weekly|DRUG: Zicronapine 30 mg once weekly|DRUG: Zicronapine 45 mg once weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Summative Assessment of the BurntOut 3D Simulation With Medical Students
Status: COMPLETED
Conditions: Burnout, Student|Alcohol; Harmful Use|Quality of Life|Depression|Resilience|Drug Use|Burnout, Professional
Interventions: OTHER: Clinical Encounters Medical School 3D Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacodynamic Activity of E2082 in Adult Participants With Photosensitive Epilepsy
Status: TERMINATED
Conditions: Photosensitive Epilepsy
Interventions: DRUG: Placebo|DRUG: E2082
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Microbiome in Asthma: Relationships to Asthma Phenotype and Inhaled Corticosteroid Treatment
Status: COMPLETED
Conditions: Asthma|Atopy
Interventions: DRUG: fluticasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Efficacy of S-adenosyl Methionine (SAMe) Versus Pentoxiphylline in Patients With Non-alcoholic Steatohepatitis With Fibrosis
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: S-adenosylmethionine (SAMe)|DRUG: pentoxiphylline (PTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Process-Specific Verbal Memory Interventions for Veterans With Tramatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Memory Strategy Training|BEHAVIORAL: Errorless Learning|BEHAVIORAL: Retrieval Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Secondary Total Elbow Arthroplasty After Failed Internal Fixation or Non-operative Treatment of Distal Humeral Fractures Achieve Equal Results as Primary Arthroplasty?
Status: COMPLETED
Conditions: Elbow Fracture|Elbow Arthropathy
Interventions: PROCEDURE: Total elbow arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Palatable Lidocaine Gel on Gag Reflex for Patients Undergoing Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Gastro-Intestinal Disorder
Interventions: DRUG: Propofol Injection [Diprivan]|DRUG: Dexmedetomidine [Precedex]|DRUG: Palatable Lidocaine Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters
Status: COMPLETED
Conditions: Anemia|Diabetes|Heart Disease|High Blood Pressure|Hypotension|Metabolic Diseases|Respiratory Diseases
Interventions: DEVICE: Non invasive peripheral blood monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics, Safety, and Tolerability Study of the Pen and PFS of SB5 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Pen of SB5|BIOLOGICAL: PFS of SB5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Repeated Dose Study With a New Insulin Glargine Formulation and Lantus® on 24-hour Glucose Profile in Japanese Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: insulin glargine (HOE901)|DRUG: insulin glargine- new formulation (HOE901)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cyclic On-off and Continuous Excimer Laser Treatment for Vitiligo
Status: COMPLETED
Conditions: Dermatologic Disease|Vitiligo
Interventions: DEVICE: The XTRAC Excimer Laser System|DRUG: Topical tacrolimus 0.1% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of G-CHOP Versus R-CHOP in Untreated Diffuse Large B-cell Lymphoma Patients
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma, Unspecified Site
Interventions: BIOLOGICAL: G-CHOP|BIOLOGICAL: R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Evaluation of the Paediatric Airway After Prior Prolonged (>24 h) Tracheal Intubation
Status: COMPLETED
Conditions: Intubation|Endoscopy
Interventions: PROCEDURE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SANTE - Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: Medtronic DBS Therapy for epilepsy|DEVICE: Medtronic DBS Therapy for epilepsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complement Inhibition Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients With Severe Thrombocytopenia
Status: COMPLETED
Conditions: Thrombocytopenia|Alloimmune Platelet Refractoriness
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Of Cervical Restorations Using Nitric Acid and Mineral Enriched Adhesive Versus Phosphoric Acid and Universal Adhesive
Status: NOT_YET_RECRUITING
Conditions: Clinical Performance
Interventions: OTHER: clean and boost enamel cleanser of vista apex , RE GEN universal adhesive from vista apex , RE GEN Bio active flowable composite form vista apex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRACK-TBI Longitudinal Biomarker Study
Status: ENROLLING_BY_INVITATION
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Telephone Outcome Assessment|BEHAVIORAL: In-Person Outcome Assessment|PROCEDURE: 3T Magnetic Resonance Imaging (MRI)|PROCEDURE: Blood Draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lidocaine Spray vs Viscous Lidocaine Solution Plus Lidocaine Spray in Patients Undergoing Non-Sedated EGD
Status: ENROLLING_BY_INVITATION
Conditions: Pain|Satisfaction, Patient
Interventions: DRUG: Lidocaine Spray|DRUG: Lidocaine Viscous+Lidocane spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Thetaburst Stimulation for the Treatment of Refractory Epilepsy - Safety, Feasibility and Proof-of-concept
Status: TERMINATED
Conditions: Epilepsies, Partial
Interventions: DEVICE: continuous thetaburst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula and Diaphragmatic Function
Status: COMPLETED
Conditions: Diaphragm Injury|Postoperative Complications
Interventions: DEVICE: High flow nasal cannula|DEVICE: Facial mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Median Effective Dose of Lidocaine for the Prevention of Pain Caused by the Injection of Propofol Formulated With Medium-/Long-chain Triglycerides
Status: COMPLETED
Conditions: Lidocaine|Injection Pain
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oncoplastic Approach to Excisional Breast Biopsies
Status: COMPLETED
Conditions: Neoplasm of Female Breast|Breast Neoplasms Diagnosis|Breast Diseases|Deformity of Reconstructed Breast
Interventions: PROCEDURE: Oncoplastic Approach Excisional Breast Biopsy|PROCEDURE: Conventional Excisional Breast Biopsy|OTHER: Tezel Method of Breast Volume Measurement|OTHER: Cosmetic Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing CABG and/or Cardiac Valve Surgery
Status: COMPLETED
Conditions: AKI
Interventions: DRUG: Low Dose RBT-1|DRUG: High Dose RBT-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postnatal Companion Support The Effect of Education on Maternal Depression and Fatigue
Status: NOT_YET_RECRUITING
Conditions: Postpartum|Fatigue|Depression|Social Support
Interventions: BEHAVIORAL: postnatal attendant training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Multiple Subcutaneous Doses of OLP-1002
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: A: OLP-1002|DRUG: B: OLP-1002|DRUG: C: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction
Status: COMPLETED
Conditions: Stem Cell|Third Molar|Periodontal Pocket
Interventions: PROCEDURE: L-PRF + DPSC|PROCEDURE: L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CLINICAL COMPARISON OF DIFFERENT GLASS IONOMER-BASED RESTORATIVES AND A BULK-FILL RESIN COMPOSITE IN CLASS I CAVITIES: A 48-MONTH RANDOMIZED SPLIT-MOUTH CONTROLLED TRIAL
Status: COMPLETED
Conditions: Class I Dental Caries
Interventions: PROCEDURE: class I restoration placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Trial Comparing Dose-dense AC-T With PC as Adjuvant Therapy for TNBC
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: epirubicin, cyclophosphamide, paclitaxel, carboplatin, G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opera® for Aromatase Inhibitor-related Arthralgia Management (AIA)
Status: COMPLETED
Conditions: Breast Cancer|Hormone Receptor Positive Tumor|Arthralgia
Interventions: DIETARY_SUPPLEMENT: OPERA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome
Interventions: DRUG: Prednisolone 20 mg/ 5 mg|DRUG: Vitamin B compound (100mg B1, 50 mg B6, 500 µg B12)|DRUG: Placebo for Vitamin B compound|DRUG: Placebo for Prednisolon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of 3 Formulations of Ondansetron in Healthy Adults (0869-095)(COMPLETED)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Comparator: Treatment A (Zofran, ondansetron)|DRUG: Comparator: Treatment B (Zofran, ondansetron)|DRUG: Comparator: Treatment C (Zofran, ondansetron)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DRUG: Iron-dextran|DRUG: Saline|PROCEDURE: Blood Donation|PROCEDURE: 24-hour PTR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Idarubicin and Lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bracing or Kinesio Taping in The Management of Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis (Tennis Elbow)
Interventions: OTHER: forearm strap (counterforce brace)|OTHER: Kinesio tape application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of CR8020 in Japanese Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: CR8020|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Wearable "Balance Booster" - Stepping Closer to the Market
Status: COMPLETED
Conditions: Distorted; Balance|Sensation Disorders|Peripheral Neuropathy|Neuropathy
Interventions: DEVICE: Walkasins ON|DEVICE: Walkasins OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Gemcitabine and Trabectedin in L-sarcomas
Status: COMPLETED
Conditions: Leiomyosarcoma|Liposarcoma
Interventions: DRUG: Gemcitabine + Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing the Specificity and Stability of Local Field Potentials in the Globus Pallidus Internus of Patients Undergoing Deep Brain Stimulation for Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Medtronic Activa PC+S Sensing Deep Brain Stimulator Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Fuquinitinib Combined With Capecitabine First-line Maintenance in the Treatment of Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Carcinoma
Interventions: DRUG: Fruquintinib、Capecitabine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Hybrid Effectiveness-Implementation Randomized Clinical Trial (RCT) of Virtual Interview Training for Autistic Transition-Age Youth
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Virtual Interview Training (VIT)|BEHAVIORAL: Services-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety Study of 4th LBVH0101 After the Primary Vaccination in LG-VHCL002 Study
Status: COMPLETED
Conditions: Infectious Disease by Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: LBVH0101 (Hib vaccine)|BIOLOGICAL: Hiberix™ Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capecitabine, Cyclophosphamide, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With HER2-Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: HER2-positive Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: capecitabine|DRUG: cyclophosphamide|DRUG: lapatinib ditosylate|BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigallocatechin Gallate (EGCG) to Improve Cognitive Performance in Foetal Alcohol Syndrome (FAS) Children
Status: COMPLETED
Conditions: Fetal Alcohol Syndrome (FAS)
Interventions: DIETARY_SUPPLEMENT: Epigallocatechin gallate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer|Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Salivary Gland Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Verrucous Carcinoma of the Larynx|Stage IV Verrucous Carcinoma of the Oral Cavity
Interventions: DRUG: lapatinib ditosylate|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302
Status: TERMINATED
Conditions: Bowel Obstruction
Interventions: DRUG: IV morphine sulfate|DRUG: EXPAREL (bupivacaine liposome injectable suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin
Status: TERMINATED
Conditions: Anticoagulants and Bleeding Disorders|Surgery|Regional Anesthesia Morbidity
Interventions: DRUG: Enoxaparin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association of Intraoperative Renal Regional Oxygen Saturation and Acute Kidney Injury
Status: COMPLETED
Conditions: Liver Transplant; Complications|Renal Injury
Interventions: DEVICE: Near-infrared spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION