pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BIP Foley in Prevention of CAUTI at Rehab Station
Status: COMPLETED
Conditions: Complications; Catheter, Urinary Infection or Inflammation
Interventions: DEVICE: BIP Foley (latex) or BIP Foley -silicone|DEVICE: Standard catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Induction of Ovulation With Raloxifene or Clomiphene Citrate in Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: clomiphene citrate|DRUG: raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Plasma Donation Frequency on Donor Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychological Distress|Protein Deficiency|Inflammation
Interventions: PROCEDURE: Plasmapheresis|PROCEDURE: Whole blood donation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Adding TCM-700C on the Standard Combination Treatment for HCV Genotype 1 Patients(Phase III)
Status: WITHDRAWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: TCM-700C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International CoolSculpting: Study to Evaluate Patient Satisfaction for Non-Invasive Fat Reduction in Abdomen and/or Flanks (iCOOL)
Status: COMPLETED
Conditions: Non-invasive Fat Reduction
Interventions: DEVICE: CoolSculpting® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flapless Mops for Acceleration of Canine Retraction
Status: COMPLETED
Conditions: Dental Malocclusions|Angle Class II, Division 1|Bimaxillary Protrusion
Interventions: PROCEDURE: Micro-osteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vilanterol on Methacholine Challenge Results
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Vilanterol and Fluticasone Furoate|DRUG: Fluticasone Furoate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Preladenant (SCH 420814) on Dyskinesia and Parkinsonism in Levodopa Treated Participants (P05550)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: SCH 420814 10 mg|DRUG: SCH 420814 100 mg|DRUG: Placebo|DRUG: Levodopa|DRUG: Carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy
Status: RECRUITING
Conditions: Facial Palsy|Facial Nerve Diseases|Borrelia Infection of Central Nervous System|Bell Palsy
Interventions: DRUG: Prednisolone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Virtual Reality on the Postoperative Balance of Adolescents With Idiopathic Scoliosis
Status: RECRUITING
Conditions: Scoliosis Idiopathic
Interventions: DEVICE: Virtual reality group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children With Developmental Language Disorder
Status: RECRUITING
Conditions: Developmental Language Disorder|Language Impairment
Interventions: BEHAVIORAL: Sentence recast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Oxcarbazepine Oral Suspension 300 mg/5 mL Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: oxcarbazepine 300 mg/5mL oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Laryngeal Mask Insertion Conditions And Hemodynamic Effects
Status: COMPLETED
Conditions: Laryngeal Masks
Interventions: DRUG: Ketamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Infectious Diseases Specialists on the Appropriateness of Antimicrobial Therapy in Surgical and Medical Wards
Status: COMPLETED
Conditions: Patients Receiving Antimicrobial Therapy
Interventions: OTHER: Infectious disease specialist advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: InterMob: a Randomized Controlled Trial Aimed at Reducing Car Use in Regular Car Users
Status: ENROLLING_BY_INVITATION
Conditions: Automobile Driving|Active Commuting
Interventions: BEHAVIORAL: InterMob: a randomized controlled trial aimed at reducing car use in regular car users|OTHER: Active control: Air pollution information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Video Chat +Personalized Feedback|BEHAVIORAL: Video Chat + Basic Feedback|BEHAVIORAL: Discussion Board for Social Support +Basic Feedback|BEHAVIORAL: Discussion Board for Social Support+Personalized Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Macular Buckle Versus Vitrectomy on Macular Schisis and Macular Detachment in Highly Myopic Eyes
Status: COMPLETED
Conditions: Retinoschisis|Macular Detachment|High Myopia
Interventions: PROCEDURE: Macular buckling|PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JR-171 in Patients With Mucopolysaccharidosis I
Status: COMPLETED
Conditions: Mucopolysaccharidosis I
Interventions: DRUG: JR-171 (lepunafusp alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effect of Warm and Cold Water Exercise Training on Vascular Function in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Warm water exercise|OTHER: Cold water exercise|OTHER: Land based cycling exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumors
Status: UNKNOWN
Conditions: Acute Leukemia|Myelodysplastic Syndrome|Solid Tumors
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|RADIATION: Total body irradiation|DRUG: Fludarabine|DRUG: cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education and Counseling Given to People With Stoma by Telephone on Stoma Compliance and Complications
Status: RECRUITING
Conditions: Stoma Colostomy
Interventions: OTHER: Education and counseling intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Intraoperative Labetalol on Time to Discharge
Status: COMPLETED
Conditions: Bloodpressure|Heart Rate
Interventions: DRUG: Esmolol|DRUG: Labetalol|DRUG: Fentanyl|OTHER: saline infusion|OTHER: 1 ml saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting
Status: RECRUITING
Conditions: Desmoid Tumor
Interventions: PROCEDURE: Cryoablation|DRUG: Chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Long-Term Effectiveness of Two Desensitizing Products
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: OTHER: Teethmate Desensitizer (TM)|OTHER: Clearfil SE Bond 2|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Canagliflozin in Older Children and Adolescents With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 50 mg|DRUG: Canagliflozin 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onset of Labour Epidural Analgesia With Different Concentration Bupivacaine and Different Doses of Sufentanyl
Status: COMPLETED
Conditions: Pregnant Women Who Requested Epidural Analgesia in the Early Stage of Labor
Interventions: DRUG: B1S5|DRUG: B125S5|DRUG: B1S10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: S. sonnei 1790GAHB|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial to Evaluate Gemcitabine and Etoposide for Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine, Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Wearable Robotic System and Robotic Mirror Therapy in Spastic Hemiplegia Post Botulinum Toxin Injection
Status: COMPLETED
Conditions: Hemiplegia, Spastic|Spastic
Interventions: PROCEDURE: BoNT-A injections|OTHER: Robotic therapy (RT)|OTHER: Robotic mirror therapy (RMT)|OTHER: Functional task training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Daily SPL-108 Injections In Conjunction With Paclitaxel in Women With Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Epithelial Cancer
Interventions: DRUG: SPL-108
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Continuous Positive Airway Pressure (CPAP) in Delivery Room, in the Prevention of Transient Tachypnea of Newborn (TTN): A Randomized Controlled Trial
Status: COMPLETED
Conditions: Transient Tachypnea
Interventions: OTHER: Prophylactic CPAP Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation of BCX10013 in Subjects With Paroxysmal Nocturnal Hemoglobinuria
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: BCX10013
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fFN & E3 in the Prediction of PTB in Women With Twin Pregnancies Receiving 17OHP or Placebo
Status: WITHDRAWN
Conditions: Preterm Delivery|Preterm Birth
Interventions: DEVICE: Fetal Fibronectin|DEVICE: Salivary Estriol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Decitabine and Tretinoin in Treating Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: decitabine|DRUG: tretinoin|GENETIC: DNA methylation analysis|GENETIC: cytogenetic analysis|GENETIC: microarray analysis|OTHER: flow cytometry|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lift Mobile Mindfulness for COVID-19 Distress Symptoms
Status: COMPLETED
Conditions: COVID-19|Cardiorespiratory Failure
Interventions: BEHAVIORAL: Lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in Lymph Node|Prostate Ductal Adenocarcinoma|Stage III Prostate Adenocarcinoma AJCC v7|Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Antiandrogen Therapy|DRUG: Axitinib|PROCEDURE: Radical Prostatectomy|PROCEDURE: Regional Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Pulmonary|Tuberculosis, Multidrug-Resistant|Tuberculosis, MDR|Tuberculosis|Drug-Resistant Tuberculosis
Interventions: DRUG: Pretomanid|DRUG: Bedaquiline|DRUG: moxifloxacin|DRUG: pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Microcirculation After Remote Ischemic Preconditioning
Status: COMPLETED
Conditions: Intact Scaphoid Bone|Intact Metacarpal Bone|Fractured Scaphoid Bone|Fractured Metacarpal Bone
Interventions: PROCEDURE: Remote Ischemic Preconditioning (by Blood Pressure Cuff)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Characterization of Intramuscular Injections of Risperidone 4 Week Long-acting Injectable (LAI) Formulation in the Buttock of Patients With Schizophrenia
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia
Interventions: DRUG: risperidone IR and LAI formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
Status: UNKNOWN
Conditions: Chronic Low-back Pain
Interventions: PROCEDURE: Radiofrequency Ablation with MEE|BEHAVIORAL: Conventional Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instaflex and Joint Pain in Community Adults
Status: COMPLETED
Conditions: Joint Pain, Stiffness, Function
Interventions: DIETARY_SUPPLEMENT: Instaflex|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
Status: RECRUITING
Conditions: Feeding Patterns|Sleep|Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Time-of-day of enteral nutrition provision (daytime first)|DIETARY_SUPPLEMENT: Time-of-day of enteral nutrition provision (nighttime first)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety Study in Healthy Volunteers to Evaluate Safety, How Fast the Drug is Absorbed, and the Side Effects of the Drug in Humans
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: GW786034|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emergency Department (ED)-Directed Interventions to Improve Asthma Outcomes
Status: COMPLETED
Conditions: Acute Asthma
Interventions: BEHAVIORAL: Opinion Leader letter|BEHAVIORAL: Involvement of a care manager|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DRUG: warfarin|DRUG: Dabigatran dose 1|DRUG: Dabigatran dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: PEG-rhG-CSF in Secondary Prevention of Nab-Paclitaxel Combined With S-1 in Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: PEG-rhG-CSF|Pancreatic Cancer
Interventions: DRUG: Jin Youli(PEG-rhG-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance Evaluation of the NaviAid™ G-Eye System
Status: COMPLETED
Conditions: Colorectal Cancer|Polyp|Adenoma
Interventions: PROCEDURE: Group A-Standard Colonoscopy, then NaviAid™ G-Eye procedure|PROCEDURE: Group B-NaviAid™ G-Eye procedure, then Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure|Diastolic Heart Failure
Interventions: DEVICE: Catheter ablation|DRUG: Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation|DEVICE: Insertion of CardioMems Hemodynamic monitor|DRUG: Empiric heart failure drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-COVID-19 With Hyperbaric Oxygen Therapy: a Randomized, Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Post-COVID-19 Syndrome|Post-COVID Syndrome|Post COVID-19 Condition|Post-COVID Condition|Post COVID-19 Condition, Unspecified|Long COVID|Long Covid19
Interventions: DRUG: Hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine Headache Mitigation Utilizing Avulux
Status: NOT_YET_RECRUITING
Conditions: Migraine|Headache|Photophobia
Interventions: DEVICE: Avulux Lenses|DEVICE: Placebo Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of Chemotherapy in Surgical Patients With Infiltrating Ductal Carcinoma of Breast
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Single agent of cyclophosphamide, doxorubicin, epirubicin, fluorouracil and methotrexate|DRUG: cyclophosphamide, doxorubicin, epirubicin, fluorouracil and methotrexate (CDEFM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoraflex Hybrid and Relay Extension Post-Approval Study
Status: RECRUITING
Conditions: Thoracic Diseases|Aortic Aneurysm|Aortic Dissection|Thoracic Aortic Aneurysm|Thoracic Aortic Dissection
Interventions: DEVICE: Thoraflex Hybrid|DEVICE: RelayPro NBS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Jamboxx Respiratory Therapy Device: Study 1
Status: WITHDRAWN
Conditions: Spinal Cord Injuries|Respiratory Complication
Interventions: DEVICE: Jamboxx Respiratory Therapy Device|DEVICE: Jamboxx Musical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Basis of Pediatric Liver Cancer
Status: RECRUITING
Conditions: Childhood Liver Cancer|Liver Malignant Tumors|Embryonal Sarcoma of Liver (Disorder)|Hepatoblastoma|Hepatocellular Carcinoma|Rhabdoid Tumor of Liver
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Patient Navigation Program for Addressing Disparities in Breast Cancer Care
Status: RECRUITING
Conditions: Breast Carcinoma|Breast Ductal Carcinoma in Situ
Interventions: BEHAVIORAL: Patient Navigation|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2
Status: COMPLETED
Conditions: Japanese Encephalitis|Japanese Encephalitis Vaccine
Interventions: BIOLOGICAL: Live attenuated Japanese encephalitis vaccine SA14-14-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Controlled Trial on Robotic Exoskeleton in Spinal Cord Injury: Clinical Outcomes and Cortical Plasticity
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: DEVICE: EKSO-GT|PROCEDURE: Standard neurorehabilitation locomotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Integrative Treatment Model to Reduce Anxiety and Depression in Minor Mental Health Problems and Medically Unexplained Symptoms
Status: COMPLETED
Conditions: Depression|Anxiety|Irritable Bowel Syndrome|Fibromyalgia
Interventions: BEHAVIORAL: Conventional treatment|OTHER: Integrative treatment|OTHER: Therapeutic acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Consumer Self-Selection and Use of Gabapentin for Occasional Sleeplessness in an Over-the-Counter Environment
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Rabeprazole on the Magnitude of the Antiplatelet Action of Clopidogrel
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A - rabeprazole|DRUG: Treatment B - omeprazole|OTHER: Treatment C - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anti-Inflammatory And Metabolic Effects Of Rosiglitazone In Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: rosiglitazone XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surgery
Status: UNKNOWN
Conditions: Cataract Surgery|Patient Satisfaction|Akinesia|Anesthesia, Local|Anesthesia; Adverse Effect|Anesthesia Recovery Period
Interventions: DRUG: Lidocaine 2% Injectable Solution 0.75 ml|DRUG: Bupivacaine Hcl 0.5% Inj 0.75 ml|DRUG: Lidocaine 2% Injectable Solution 1.5 ml|DRUG: Bupivacaine Hcl 0.5% Inj 1.5 ml
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Registry of Patients Diagnosed With Lysosomal Storage Diseases
Status: RECRUITING
Conditions: Mucopolysaccharidosis I|Mucopolysaccharidosis II|Mucopolysaccharidosis IV A|Mucopolysaccharidosis VI|Mucopolysaccharidosis VII|Pompe Disease Infantile-Onset|Neuronopathic Gaucher Disease|Wolman Disease
Interventions: OTHER: There is no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vancomycin Dosage Adjustment for MRSA Infections
Status: UNKNOWN
Conditions: Methicillin-Resistant Staphylococcus Aureus
Interventions: DRUG: Vancomycin equation-based method|DRUG: Vancomycin trough concentration method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Low-level Laser Therapy
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rehabilitation|Rotator Cuff Injuries
Interventions: OTHER: In addition to the conservative treatment, Low-level laser therapy|OTHER: In addition to the conservative treatment, Low-level laser therapy (turned off)|OTHER: Conservative treatment solely
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent and Infant Inter(X)Action Intervention (PIXI)
Status: ENROLLING_BY_INVITATION
Conditions: Fragile X Syndrome|Angelman Syndrome|Prader-Willi Syndrome|Dup15Q Syndrome|Duchenne Muscular Dystrophy|Phelan-McDermid Syndrome|Rett Syndrome|Smith Magenis Syndrome|Williams Syndrome|Turner Syndrome|Klinefelter Syndrome|Chromosome 22q11.2 Deletion Syndrome|Tuberous Sclerosis|Down Syndrome
Interventions: BEHAVIORAL: Parent-Infant Inter(X)action Intervention (PIXI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps
Status: NOT_YET_RECRUITING
Conditions: Maxillary Neoplasms
Interventions: PROCEDURE: scapular free flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Comparative Trial of the ASR™-XL Acetabular Cup System vs. the Pinnacle™ Metal- on- Metal Total Hip System
Status: COMPLETED
Conditions: Non-inflammatory Degenerative Joint Disease
Interventions: DEVICE: ASR™-XL Modular Acetabular Cup System|DEVICE: Pinnacle™ acetabular shell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Haemodynamic Response to General Anaesthesia in Healthy Orthopaedic Patients
Status: COMPLETED
Conditions: Hypotension
Interventions: DEVICE: LiDCO rapid™ CNAP monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: anakinra|DRUG: pegsunercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial)
Status: TERMINATED
Conditions: SIRS (Systemic Inflammatory Response Syndrome(
Interventions: PROCEDURE: Goal-directed Therapeutic Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Albumin Interferon Administered Every 4 Weeks in Genotype 2/3 Hepatitis C Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: alb-interferon alfa 2b|DRUG: alb-interferon alfa 2b|DRUG: alb-interferon alfa 2b|DRUG: alb-interferon alfa 2b|DRUG: peg-interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
Status: RECRUITING
Conditions: COVID-19 Infection|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fenretinide in Preventing Ovarian Cancer in Participants Who Are at High Risk for Developing Ovarian Cancer and Planning to Undergo Surgery to Remove the Ovaries
Status: COMPLETED
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Ovarian Cancer
Interventions: DRUG: fenretinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Paroxetine and Interpersonal Psychotherapy for Maintaining Health and Well-being in Elderly Individuals With Depression
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: BEHAVIORAL: Interpersonal Psychotherapy|DRUG: paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcriptomic Landscape of T Lymphocytes of Atopic Dermatitis, Atopic Prurigo Nodularis (of Besnier) and Non-atopic Prurigo Nodularis (of Hyde) Using Single Cell RNA-sequencing
Status: UNKNOWN
Conditions: Prurigo Nodularis|Atopic Dermatitis
Interventions: OTHER: Skin biopsy|OTHER: Plastic surgery remnants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multisite Exploration of Balance Perturbations With and Without Body Weight Support
Status: TERMINATED
Conditions: Stroke|Stroke, Acute|Balance; Distorted|Balance; Impairment|Gait, Unsteady
Interventions: DEVICE: Body weight support system control group|DEVICE: Body weight support system with balance perturbations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Technological Oral Health Management
Status: NOT_YET_RECRUITING
Conditions: Oral Health|Malnutrition|Dysphagia|Sarcopenia
Interventions: BEHAVIORAL: oral mastication training|BEHAVIORAL: texture and diet education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Cardiorenal Syndrome|Cardio-Renal Syndrome|ADHF|Heart Failure, Systolic|Heart Failure, Diastolic|Heart Failure; With Decompensation|Heart Failure, Congestive
Interventions: DEVICE: Aortix System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Vitamin C Reduce the Risk of Postoperative Shoulder Stiffness?
Status: TERMINATED
Conditions: Shoulder Stiffness
Interventions: DRUG: Vitamin C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: duoABLE for People With Stroke and Their Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Stroke Ischemic|Stroke Hemorrhagic|Stroke Sequelae
Interventions: BEHAVIORAL: duoABLE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-Dotatoc Positron Emission Tomography (PET) for Somatostatin Receptor-Positive Neuroendocrine Tumors (NETs)
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Carcinoid Tumors
Interventions: DRUG: 68Ga-DOTATOC PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )
Status: COMPLETED
Conditions: Type A Aortic Dissection
Interventions: OTHER: No Intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Acellular and Whole-Cell Pertussis Vaccines
Status: COMPLETED
Conditions: Pertussis
Interventions: BIOLOGICAL: diphtheria-tetanus-pertussis vaccine containing whole-cell pertussis|BIOLOGICAL: diphtheria-tetanus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Pyroxamide in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: pyroxamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of the Use of Ultrasound for Epidural Catheter Placement and Comparison With Palpation Technique
Status: ACTIVE_NOT_RECRUITING
Conditions: Labor Pain
Interventions: DEVICE: ultrasound guidance|DEVICE: palpation guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.
Status: UNKNOWN
Conditions: Craniocerebral Trauma|Traumatic Brain Injury|Subarachnoid Hemorrhage|Anoxic Brain Injury
Interventions: BEHAVIORAL: Tilt Table With Integrated Stepping System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Bioequivalence Study of Topically Delivered Clobetasol Propionate Lotion in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clobetasol Propionate 0.05% lotion, single exposure|DRUG: Clobex TM 0.05% Lotion, single exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Brooke Bond Black Tea Extract on Flow Mediated Dilation in Indian Males
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Nutrition intervention study with a black tea extract|OTHER: Nutrition intervention study with a control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury
Status: ENROLLING_BY_INVITATION
Conditions: NSSI
Interventions: OTHER: rTMS stimulation of right IPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia
Status: WITHDRAWN
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: Liposuction|OTHER: Stem Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing a 3D Printed Model of the Mediastinum to Teach Thoracic Anatomy to Medical Trainees
Status: COMPLETED
Conditions: Anatomy Teaching Methods
Interventions: OTHER: 3D Mediastinum Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Comprehensive Fall Prevention Protocol (CARE: Cognitive-Aerobic-Resistance-Exer-gaming) on Mobility Level in Elderly
Status: UNKNOWN
Conditions: Fall Injury|Fall Patients|Geriatric Fall|Physical Therapy|Balance Traiing
Interventions: OTHER: electrotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nafamostat in Covid-19 Patients (RACONA Study)
Status: RECRUITING
Conditions: COVID19
Interventions: DRUG: Nafamostat Mesilate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Prevention Hepatocellular Carcinoma by Metformin
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Hepatitis C, Chronic|Cirrhosis
Interventions: DRUG: Metformin|DRUG: placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Treatment of Recurrent Upper GI Bleeding: OTSC [Over the Scope Clip] Versus Standard Therapy
Status: UNKNOWN
Conditions: Acute Upper Gastrointestinal Hemorrhage
Interventions: DEVICE: Endoscopic hemostasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mid Range Ejection Fraction|Amyloid Cardiomyopathy
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Assessing the Effect of Tildrakizumab in Vitiligo
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin and Connective Tissue Diseases|Skin Diseases|Pigmentation Disorder|Hypopigmentation|Biologic|Vitiligo
Interventions: DRUG: Tildrakizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Cancer
Interventions: DRUG: Isatuximab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronavirus (COVID-19) ACEi/ARB Investigation
Status: SUSPENDED
Conditions: Hypertension|COVID-19
Interventions: DRUG: Thiazide or Thiazide-like diuretics|DRUG: Calcium Channel Blockers|DRUG: ACE inhibitor|DRUG: Angiotensin receptor blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Awareness For Empowerment (SAFE): An RCT With Young People Experiencing Homelessness
Status: COMPLETED
Conditions: Substance Use|Victimization
Interventions: BEHAVIORAL: Safety Awareness For Empowerment (SAFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Carotid Stenosis|Abdominal Aortic Aneurysm
Interventions: OTHER: patients with newly diagnosed PAD (<1year)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Dose Escalation: Solid Tumors|MTD: Soft Tissue Sarcomas
Interventions: DRUG: PXD101|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Status: COMPLETED
Conditions: Delirium|Cognitive Impairment|Post-traumatic Stress Disorder|Depression|Anxiety
Interventions: DRUG: Haloperidol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study
Status: COMPLETED
Conditions: Hemodialysis|Hyperphosphatemia
Interventions: DRUG: Lanthanum Carbonate|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Tumor|Ovarian Seromucinous Carcinoma|Ovarian Serous Tumor|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Ovarian Endometrioid Adenocarcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Cediranib Maleate|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Olaparib|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leptin Infusion and Endothelial Vasomotor Response
Status: COMPLETED
Conditions: Endothelial Dysfunction|Obesity|Vasodilation|Venous Occlusion Plethysmography
Interventions: DRUG: Leptin infusion plus vasodilators in healthy men|DRUG: Leptin infusion in healthy men|DRUG: Vasodilators in CAD patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bilateral Breast Carcinoma|HER2/Neu Negative|Invasive Breast Carcinoma
Interventions: OTHER: Best Practice|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Measure the Safety of 68Ga-DOTA-TATE PET/CT in the Diagnosis of Tumors Expressing Somatostatin Receptors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: OTHER: Gallium-68 DOTA TATE PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Behavioral Therapy Versus Ericksonian Hypnosis Therapy for Depression and Anxiety Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Ericksonian Hypnotehrapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteriuria Eradication Through Probiotics
Status: UNKNOWN
Conditions: Bacteriuria
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 827
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: 700 mg IV|DRUG: 350 mg SC|DRUG: Placebo|DRUG: 140 mg SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
Status: UNKNOWN
Conditions: Stroke|COVID-19|Frailty|Muscle Weakness|Sarcopenia
Interventions: OTHER: Ghostly app|OTHER: Blood flow restriction|OTHER: Leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Euphrasia Eye Drops in Preterm Infants With First Signs of Congestion of Nasolacrimal Duct
Status: COMPLETED
Conditions: Congenita Nasolacrimal Duct Obstruction|Preterm Neonates|Ocular Discharge
Interventions: DRUG: Euphrasia Officinalis Preparation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of EGFR-TKI for Residual Lesions of Multiple Synchronous Ground-glass Opacities
Status: UNKNOWN
Conditions: Multiple Primary Lung Cancers
Interventions: DRUG: furmonertinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT