pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized, Placebo-controlled, Double Blind Trial to Investigate Whether Vitamin K2 Can Influence Arterial Calcification in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Arterial Calcification|Diabetes Mellitus Type 2
Interventions: DIETARY_SUPPLEMENT: Menaquinone-7|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SpHincterotomy for Acute Recurrent Pancreatitis
Status: RECRUITING
Conditions: Pancreatitis|Pancreas Divisum|Pancreatitis, Acute|Pancreatitis Idiopathic|Pancreas Inflamed
Interventions: PROCEDURE: ERCP with miES|PROCEDURE: EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach
Status: RECRUITING
Conditions: Schistosoma Mansoni
Interventions: DIAGNOSTIC_TEST: Molecular biology analyses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Pulmonary Rehabilitation on Bronchoscopic Volume Reduction Process Success
Status: COMPLETED
Conditions: Emphysema|Pulmonary Rehabilitation|Bronchoscopic Lung Volume Reduction
Interventions: OTHER: Pulmonary Rehabilitation|OTHER: Standart care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Cat-PAD Follow-on Study
Status: COMPLETED
Conditions: Cat Allergy
Interventions: DRUG: Received Cat-PAD Treatment 1 in Study CP007 [NCT01620762]|DRUG: Received Cat-PAD Treatment 2 in Study CP007 [NCT01620762]|DRUG: Received Cat-PAD Treatment 3 in Study CP007 [NCT01620762]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Educational Intervention Aimed at Increasing the Emotional Competencies of Patients Under Surveillance After Antineoplastic Treatment of Oesogastric or Bronchopulmonary Cancer
Status: UNKNOWN
Conditions: Digestive System Neoplasms|Thoracic Neoplasms
Interventions: BEHAVIORAL: Emotional skills|BEHAVIORAL: Short free talk and relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: 250 mg/m2 aldoxorubicin|DRUG: 350 mg/m2 aldoxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Auricular Acupuncture in Reducing Dental Anxiety and Pain Perception During Orthodontic Extractions Among Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Anxiety
Interventions: PROCEDURE: Auricular acupunctures|PROCEDURE: Sham acupunctures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Nesiritide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma
Status: COMPLETED
Conditions: High Grade Glioma
Interventions: DRUG: nanoliposomal irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FDG-PET/CT in Evaluation of Cytological Indeterminate Thyroid Nodules to Prevent Unnecessary Surgery (EfFECTS)
Status: COMPLETED
Conditions: Thyroid Nodule|Thyroid Neoplasms
Interventions: PROCEDURE: Diagnostic Thyroid Surgery|DEVICE: Ultrasound of the head and neck|RADIATION: FDG-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery
Status: RECRUITING
Conditions: Analgesics, Opioid|Anesthesia, Endotracheal|Anesthesia, General
Interventions: OTHER: anesthesia without opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thiopental Versus Propofol During Magnetic Resonance Imagining in Children: Something Old, Something New
Status: UNKNOWN
Conditions: Complications
Interventions: DRUG: Propofol and Thiopental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma
Status: RECRUITING
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant|Metastatic Malignant Neoplasm in the Central Nervous System|Recurrent Diffuse Intrinsic Pontine Glioma|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Osteosarcoma|Recurrent Primary Malignant Central Nervous System Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Osteosarcoma|Refractory Primary Malignant Central Nervous System Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspirate|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Echocardiography|DRUG: FACT Complex-targeting Curaxin CBL0137
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors
Status: COMPLETED
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: MTX|DRUG: Ara-C|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Content of Gluten Diet on Patients With Irritable Bowel Syndrome (Pro.Ali.Fun.)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: Reduced gluten bread and Pasta compared o normal gluten bread and Pasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold
Status: COMPLETED
Conditions: Common Cold|Headache|Nasal Congestion
Interventions: DRUG: Pseudoephedrine/Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Self-assessment vs. Assessment by Others of Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Self-Assessment|Assessment, Self
Interventions: OTHER: WHODAS 2.0|OTHER: EQ5D|OTHER: IADL|OTHER: Barthel-Score|OTHER: SF-36|OTHER: MoCA Blind
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Reminders in Test Reports to Improve Guideline Compliance
Status: COMPLETED
Conditions: Echocardiography
Interventions: OTHER: Statement|OTHER: No Statement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Safety and Efficacy of Polyethylene Glycol (PEG) Mediated Fusion (PEG Fusion)
Status: RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: DRUG: NTX-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Mononuclear Cells vs Mesenchymal Stem Cells in Diabetic Patients With Chronic Limb Ischemia
Status: COMPLETED
Conditions: Chronic Limb-threatening Ischemia|Diabetes Mellitus
Interventions: BIOLOGICAL: Cell-based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pimozide Augmentation for Clozapine Partial Response
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Pimozide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mass Balance Study of JTZ-951 in Subjects With End-stage Renal Disease on Hemodialysis
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: JTZ-951, 14C-JTZ-951
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: irinotecan hydrochloride|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: radiation therapy|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery
Status: UNKNOWN
Conditions: Liposomal Bupivacaine|Postoperative Pain|Forefoot Surgery|Opioid Use|Bunion
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Randomized Study of GEMOX With or Without Cetuximab in Locally Advanced and Metastatic BTC
Status: COMPLETED
Conditions: Cholangiocarcinoma|Adenocarcinoma of Gallbladder
Interventions: DRUG: gemcitabine, oxaliplatin|DRUG: cetuximab, gemcitabine, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children
Status: COMPLETED
Conditions: Status Epilepticus|Generalized Convulsive Status Epilepticus|Status Epilepticus, Generalized|Status Epilepticus, Generalized Convulsive
Interventions: DRUG: Levetiracetam|DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial: BIBF 1120 Added to Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia (AML)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: triple kinase inhibitor BIBF1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy for Improving Post-Surgical Quality of Life
Status: COMPLETED
Conditions: Quality of Life|Anxiety Postoperative
Interventions: OTHER: Lavender peppermint elequil aromatab|OTHER: Sweet almond oil elequil aromatab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Protocol for Muscular Foot Strengthening On a Capacity to Control the Deformation of the DOT Plantar Medial
Status: COMPLETED
Conditions: Foot Diseases
Interventions: OTHER: Exercise for Foot Strengthening|OTHER: Exercise for Foot Strengthening and Electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: ezetimibe|DRUG: simvastatin|DRUG: Placebo (Unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gossypol Acetic Acid With Lenalidomide and Dexamethasone in Treating Patients With Relapsed Symptomatic Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Pharmacological Study|DRUG: R-(-)-Gossypol Acetic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1% / timolol 0.5% Fixed Combination|DRUG: Habitual prostaglandin monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery
Status: UNKNOWN
Conditions: Agitation|Child|Anesthesia
Interventions: BEHAVIORAL: eye patch|BEHAVIORAL: non-eye patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cholera Toxin B Subunit (CTB) Administered by Mucosal Way in Healthy Adult Volunteer
Status: COMPLETED
Conditions: Infection
Interventions: BIOLOGICAL: CTB by nasal way|BIOLOGICAL: absorption of CTB by oral way|BIOLOGICAL: absorption of dukoral by oral way|BIOLOGICAL: absorption of CTB by sublingual way|BIOLOGICAL: absorption of CTB by sublingual way
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of N-acetylcysteine on Preservation Solution During Liver Transplantation
Status: COMPLETED
Conditions: Unspecified Complication of Liver Transplant
Interventions: DRUG: N-acetylcysteine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Participants With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Computer- administered test battery|DEVICE: Examiner- administered test battery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home Sleep Therapy for Older Adults With MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Sleep|Transcranial Electrical Stimulation|Machine Learning|Memory
Interventions: DEVICE: Transcranial Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants
Status: TERMINATED
Conditions: Malaria, Falciparum
Interventions: DRUG: MMV390048 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RItuximab Versus FUmarate in Newly Diagnosed Multiple Sclerosis.
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Rituximab|DRUG: Dimethyl fumarate|DRUG: Sodium Chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wearable Lower Extremity Exoskeleton to Promote Walking in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Ekso® (Wearable lower limb exoskeleton)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Better Contraceptive Choices: Immediate or Delayed Insertion of IUC After Second Trimester Abortion
Status: UNKNOWN
Conditions: Pregnancy
Interventions: PROCEDURE: Immediate insertion|PROCEDURE: Interval insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Biofeedback-Assisted Pelvic Muscle Floor Training and Electrical Stimulation on Women With Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence|Urethral Hypermobility|Intrinsic Sphincter Deficiency
Interventions: BEHAVIORAL: surface electromyographic biofeedback assisted pelvic floor muscle training|BEHAVIORAL: surface electromyographic biofeedback and electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Hypertonic Saline for Mechanically Ventilated Children
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: Hypertonic saline (3%)|DRUG: Placebo (0.9% saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IB Lung Non-Small Cell Carcinoma AJCC v7|Stage II Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|BIOLOGICAL: Nivolumab|OTHER: Observation|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: external oblique intercostal block|PROCEDURE: Erector Spine block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin D Supplementation on Metabolic Syndrome Indicators Among Older Adults, Alborz Province, Iran
Status: COMPLETED
Conditions: Vitamin D Deficiency|Diabetes Mellitus|Hypertension|Lipid Metabolism Disorders|Obesity, Abdominal
Interventions: DRUG: D-vitin, soft gelatin capsule (vitamin D3,50000 IU)|DRUG: Placebo vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PSA TOOL for Prostate Cancer Screening Discussions
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: PSA TOOL|BEHAVIORAL: Revised PSA TOOL|BEHAVIORAL: Informal Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexamethasone for Post Uterine Artery Embolization Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Leiomyoma
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of QMF149 (150/80 µg) Compared With MF Twisthaler® (200 µg) in Patients With Asthma
Status: COMPLETED
Conditions: Mild Asthma
Interventions: DRUG: QMF149 150/80 μg|DRUG: MF 200 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Status Migrainosus - Differentiating Between Responders and Non-responders
Status: UNKNOWN
Conditions: Migraine
Interventions: DRUG: Bupivacaine|DRUG: Naratriptan Pill|DRUG: Dexamethasone|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Video-based Exercise on Premenstrual Symptoms: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Premenstrual Syndrome|Stress
Interventions: OTHER: Pilates Based Exercises|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial For SARS-CoV-2 Vaccine (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: CoronaVac|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a New Supraglottic Airway With Built-in Cuff Pressure Indicator
Status: COMPLETED
Conditions: The Study Focuses on the Effect of a New Supraglottic Airway With Built-in Cuff Pressure Indicator on Postoperative Pharyngolaryngeal Adverse Events
Interventions: DEVICE: LMA|DEVICE: Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study on the Effect of Inulin in Infant Formula on Gut Health
Status: COMPLETED
Conditions: Healthy Infants
Interventions: OTHER: Powder based infant formula|OTHER: Powder based infant formula|OTHER: Powder based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comutti - A Research Project Dedicated to Finding Smart Ways of Using Technology for a Better Tomorrow for Everyone, Everywhere.
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: Clinical evaluation of participants by means of Autism Diagnostic Observation Schedule|BEHAVIORAL: audio signal dataset creation and validation; machine learning analysis, empirical evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Implantation of the End-vascular Creation of the Arteriovenous Fistulas in Patients in the University Hospital of Araba. Pilot Study.
Status: UNKNOWN
Conditions: Efficacy and Safety
Interventions: PROCEDURE: endoFAVI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single-sided Deafness and Cochlear Implantation
Status: COMPLETED
Conditions: Hearing Loss|Hearing Loss, Sensorineural|Hearing Loss, Unilateral|Hearing Loss, Sudden|Hearing Loss, Cochlear|Hearing Loss in Left Ear|Hearing Loss in Right Ear|Labyrinthitis
Interventions: DEVICE: Cochlear implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy and Tolerability of Autologous Adipose Tissue Derived Stem Cells on Facial Rejuvenation
Status: COMPLETED
Conditions: Skin Rejuvenation
Interventions: PROCEDURE: intradermal injection of adipose derived stem cells to one side of the face|PROCEDURE: intradermal injection of saline to one side of the face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: arimoclomol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nitric Oxide on Spatial Working Memory in Patients With Schizophrenia - Pilot Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Sodium Nitroprusside infusion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Treatment of Atrial Fibrillation (AF) Between Surgical Ultrasonic Technology or Drug Therapy for Patients With AF Requiring Mitral Valve Surgery
Status: TERMINATED
Conditions: Mitral Valvulopathy|Atrial Fibrillation
Interventions: DEVICE: EPICOR|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Intraoperative Electrical Stimulation for Prevention of Shoulder Dysfunction After Oncologic Neck Dissection
Status: COMPLETED
Conditions: Shoulder Pain|Head Neck Cancer
Interventions: DEVICE: Grass SD9 Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery
Status: COMPLETED
Conditions: Alveolar Bone Loss|Periodontal Diseases
Interventions: DEVICE: beta-tricalcium phosphate alone|DEVICE: GFeBGS 0.1%|DEVICE: GFeBGS 0.3%|DEVICE: GFeBGS 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wild-Type Reovirus in Combination With Carfilzomib and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Anemia|Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pelareorep
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery
Status: COMPLETED
Conditions: Strabismus
Interventions: DRUG: subtenons anesthetic - preservative-free bupivacaine 0.75%|DRUG: topical anesthetic - 0.5 cc of lidocaine 3.5% ophthalmic gel|DRUG: topical control - 0.5 cc of Hypromellose 0.3% gel|DRUG: subtenons control - 0.5 cc of Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vascular Effects of Alirocumab in Acute MI-Patients
Status: COMPLETED
Conditions: Coronary Vessel|Coronary Circulation|Atheroma; Myocardial
Interventions: DRUG: Alirocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ChimeriVax™-Japanese Encephalitis Vaccine in Toddlers in Thailand and the Philippines
Status: COMPLETED
Conditions: Japanese Encephalitis|Hepatitis A
Interventions: BIOLOGICAL: Japanese encephalitis vaccine|BIOLOGICAL: Japanese encephalitis vaccine|BIOLOGICAL: Japanese encephalitis vaccine|BIOLOGICAL: Japanese encephalitis vaccine (Acambis)|BIOLOGICAL: Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Itraconazole on the Pharmacokinetics and Safety of Dazucorilant in Healthy, Adult Participants
Status: RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: Dazucorilant|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Bisphosphonate for Osteopenic Women Treated With Adjuvant Aromatase Inhibitors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ibandronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Status: WITHDRAWN
Conditions: Geographic Atrophy|Age Related Macular Degeneration
Interventions: DRUG: IONIS-FB-Lrx|DRUG: Placebo (sterline saline 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fascia Iliaca Compartment Block (FICB) on QoR-15 Score in Partial Hip Arthroplasty Surgery
Status: COMPLETED
Conditions: Post Operative Pain|Anesthesia, Local|Fracture of Hip|QoR-15
Interventions: DRUG: Bupivacain (preoperative)|DRUG: Bupivacaine-fentanyl|DRUG: Bupivacain (Postoperative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Trastuzumab In Patients With HER2 Positive Persistent Or Recurrent Vulvar Paget's Disease
Status: WITHDRAWN
Conditions: Paget's Disease of the Vulva
Interventions: DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adding Dexmedetomidine in Ultrasound-guided Intermediate Cervical Plexus Block for Thyroidectomy Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Cancer of Larynx
Interventions: DRUG: dexmedetomidine|DRUG: bupivacaine 0.25%|PROCEDURE: Thyroidectomy Surgery|PROCEDURE: Ultrasound-guided intermediate Cervical Plexus Block Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nalbuphine Versus Morphine for Perioperative Tumor Ablation
Status: RECRUITING
Conditions: Nalbuphine Allergy|Ablation|Safety
Interventions: DRUG: Nalbuphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FASter Insulin in Closed-loop Technology in Children
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: CamAPS FX using faster insulin aspart|DEVICE: CamAPS FX using standard insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROPHYSOME: Pilot Study on Safety of a Weekly Administration of 10mg/kg of AmBisome® in Antifungal Prophylaxis Treatment of Allogeneic Stem-cell Transplantation and Acute Leukaemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Ambisome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Iberdomide|BIOLOGICAL: Belantamab Mafodotin|DRUG: Dexamethasone|PROCEDURE: Echocardiography|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study With a Novel PanCytoVir™ Oral Suspension (100 mg/ml)
Status: NOT_YET_RECRUITING
Conditions: Relative Bioavailability
Interventions: DRUG: PanCytoVir™ 100 mg/mL oral suspension|DRUG: Probenecid 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Major Gynecologic and Urologic Surgery
Status: TERMINATED
Conditions: Hysterectomy|Cystectomy|Regional Anesthesia
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)
Status: COMPLETED
Conditions: Ovarian Cancer|Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Oral rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma
Status: COMPLETED
Conditions: Relapsed Ewing Sarcoma|Refractory Ewing Sarcoma
Interventions: DRUG: Linsitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Radiotherapy in the Treatment of Oligometastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Adaptive Dispenser Initiation Protocols for MySafeRx During Post-detox Buprenorphine Treatment- a Pilot Study
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: OTHER: MySafeRx Inspire Plus|OTHER: MySafeRx Inspire Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IV Pancreatic Cancer
Interventions: DRUG: sorafenib tosylate|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies
Status: TERMINATED
Conditions: Thymoma|Thymic Carcinoma
Interventions: DRUG: PXD101with cisplatin+doxorubicin+cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib, Obinutuzumab and Lenalidomide in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Newly Diagnosed
Interventions: DRUG: Zanubrutinib|DRUG: Lenalidomide|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Heated Lidocaine/Tetracaine Topical Patch in Treatment of Patients With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: DRUG: Heated lidocaine and tetracaine topical patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate Efficacy and Safety of the IMP in Patients With Non Healing Wounds Originating From Ulcers
Status: TERMINATED
Conditions: Skin Ulcer Venous Stasis Chronic
Interventions: BIOLOGICAL: APZ2 application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JY025 is a First-line Treatment for EGFR Mutated NSCLC Phase II and III Clinical Trials of Efficacy and Safety
Status: UNKNOWN
Conditions: NSCLC
Interventions: BIOLOGICAL: Recombinant anti-VEGFR2 fully human monoclonal antibody (JY025)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methyl Aminolevulinate 8% and 16% Incubated by 1 and 3 for Actinic Keratoses Treatment
Status: NOT_YET_RECRUITING
Conditions: Actinic Keratoses
Interventions: PROCEDURE: light curettage|OTHER: Pre irradiation of 1 hour|OTHER: Pre irradiation of 3 hour|OTHER: topical application of 8% methyl aminolevulinate photosensitizer MAL|OTHER: topical application of 16% methyl aminolevulinate photosensitizer (MAL)|DEVICE: Visible light source
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Etanercept in the Treatment of Subjects With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Enbrel (etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neural and Cognitive Correlates of Pragmatic Abilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Right Hemispheric Stroke|Left Hemispheric Stroke|Traumatic Brain Injury|Right Hemispheric Brain Tumor|Left Hemispheric Brain Tumor|Mild Cognitive Impairment|Healthy
Interventions: OTHER: Neuropsychological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regenerative Endodontic Therapy in Cases of Irreversible Pulpitis
Status: RECRUITING
Conditions: Symptomatic Irreversible Pulpitis
Interventions: PROCEDURE: regenerative endodontic therapy using I-PRF|PROCEDURE: blood clot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aligning With Schools To Help Manage Asthma (Project ASTHMA)
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Asthma Assessment & Management|OTHER: Asthma Education|OTHER: Controller medication at school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Value of Inguinal Exploration for Impalpable Testes
Status: NOT_YET_RECRUITING
Conditions: Undescended Testis|Inguinal; Testicle
Interventions: PROCEDURE: Inguinal exploration|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glizigen-Viudid-External Anogenital Warts in Children and Adolescents
Status: COMPLETED
Conditions: External Anogenital Warts
Interventions: DIETARY_SUPPLEMENT: Glizigen + Viusid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas
Status: RECRUITING
Conditions: Small Cell Lung Cancer|Neuroendocrine Carcinoma
Interventions: DRUG: RO7616789|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between FS- LASIK and FS-SMILE for Correction of Myopia and Myopic Astigmatism
Status: UNKNOWN
Conditions: Myopia
Interventions: PROCEDURE: FS-SMILE|PROCEDURE: FS- LASIK|DEVICE: Visumax device|DEVICE: FS 200 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Bifidobacterium Animalis Ssp Lactis DR10 Supplementation in Women During Pregnancy and Lactation on Breast Milk IL-8 and Gut Mucosa Integrity in Infant
Status: COMPLETED
Conditions: Bifidobacterium
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts
Status: RECRUITING
Conditions: Tobacco Use Cessation
Interventions: DRUG: Nicoderm CQ 21Mg/24Hr Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Postoperative Sedation in Patients Undergoing Repair of Thoracoabdominal Aortic Aneurysms
Status: TERMINATED
Conditions: Sedation|Respiration, Artificial|Length of Stay
Interventions: DRUG: Dexmedetomidine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: AMG 732|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluciclovine-PET/CT for Bone Metastases From Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: F-18 fluciclovine-PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson Patients
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: Duloxetine|DRUG: Donepezil|DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: pain pump containing ropivacaine|DEVICE: saline pain pump with injectable medication|DRUG: ropivacaine, ketorolac , morphine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Techniques in Injection Site Spotting for Botulinum Toxin Injections: Echography or Electro Stimulation.
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Botulinum toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TAILored Versus COnventional AntithRombotic StratEgy IntenDed for Complex HIgh-Risk PCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Stenoses
Interventions: DRUG: Tailored antithrombotic strategy|DRUG: Conventional antithrombotic strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Efficacy and Safety of Amaryl M and Metformin Uptitraion to Type 2 DM
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glimepiride/metformin fixed combination|DRUG: Metformin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial of Shenbai Granules in Reducing Recurrence of Colorectal Adenoma
Status: COMPLETED
Conditions: Gastroenterology
Interventions: DRUG: Shenbai Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Impact of Mini-exchange-room and Usual Care on Physical Activity and Quality of Life in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Physical Activity|Quality of Life
Interventions: DEVICE: mini-exchange-room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Remote Ischemic Preconditioning on Collaterals of Atherosclerosis Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: DEVICE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study Designed to Evaluate the Relative Risk of Two Colonoscopy Schedules for Patients With Small Polyps
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Feasibility of Delivering Consumer-based Meditation Applications to Myeloproliferative Neoplasm Patients
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm
Interventions: BEHAVIORAL: Calm App Meditation|BEHAVIORAL: Unnamed Consumer-Based App Meditation|OTHER: Educational Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE