pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low-Intermediate-Glycemic Index Caribbean Foods Versus High Glycemic Index Foods in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Inflammation|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Low-Intermediate-Glycemic Index diets|DIETARY_SUPPLEMENT: High GI diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0359 in Patients With Chronic Obstructive Pulmonary Disease (COPD)(0359-016)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: MK0359
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Irreversible Electroporation for Unresectable Hepatic Carcinoma in Poor Liver Function
Status: COMPLETED
Conditions: Hepatic Carcinoma
Interventions: DEVICE: NanoKnife LEDC System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients
Status: COMPLETED
Conditions: Non-melanoma Skin Cancer
Interventions: BIOLOGICAL: HP802-247|BIOLOGICAL: Bacitracin Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of LSCD With DM
Status: RECRUITING
Conditions: Limbal Stem-cell Deficiency|Congenital Aniridia
Interventions: PROCEDURE: transplantation of a Descemet's Membrane corneal onlay, partial LSCD|PROCEDURE: transplantation of a Descemet's Membrane corneal onlay, total/near-total LSCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients
Status: RECRUITING
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: Lactoferrin|DRUG: Ferrous Glycine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
Status: NOT_YET_RECRUITING
Conditions: Age-related Wet Macular Degeneration
Interventions: DRUG: CG-P5 peptide|DRUG: Placebo|DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants
Status: TERMINATED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Aerosolized lucinactant|DRUG: Aerosolized lucinactant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Respiratory Physiotherapy in Mitral Valve Surgery
Status: COMPLETED
Conditions: Mitral Valve Disease
Interventions: OTHER: breathing exercises|DEVICE: incentive spirometry|DEVICE: Intermittent positive pressure breathing|DEVICE: Continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enasidenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia With an IDH2 Gene Mutation
Status: WITHDRAWN
Conditions: Blasts Under 5 Percent of Peripheral Blood White Cells|Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment Level|IDH2 Gene Mutation|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Enasidenib|PROCEDURE: Hematopoietic Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Confirmatory Study Confirming Performance of a New Intermittent Catheter
Status: COMPLETED
Conditions: Urinary Retention
Interventions: DEVICE: Investigational device - intermittent catheter with micro-hole zone|DEVICE: Comparator - standard intermittent catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Active Detection of the Extension of Atherothrombosis in High Risk Coronary Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Arterial doppler for screening asymptomatic and significant extracoronary arterial stenoses in all arterial beds|OTHER: Conservative arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Cetuximab, and Cisplatin With IMRT (Intensity-Modulated Radiation Therapy) for Patients With Stage III/IV Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: bevacizumab, cisplatin, cetuximab, radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micropulse 810 Nanomolar (nm), Diode Laser for Diffuse Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination of Oxaliplatin, Capecitabine, and Celecoxib With Concurrent Radiation for Rectal Cancer
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: OTHER: Chemotherapy, Celecoxib, and Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tacrolimus/Methotrexate and Tocilizumab to Prevent Acute Graft-Versus-Host Disease (AGVD) After Allogeneic Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Tacrolimus|DRUG: Methotrexate|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial To Evaluate the Toxicity and Antiviral Effects of a Range of Doses of Ampligen in p24 Antigen Positive HIV-Infected Patients With AIDS or ARC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ampligen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Sacubitril/Valsartan in Post-acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Soluble Dietary Fiber on Sport Efficiency and Fatigue Delay in Top Basketball Players
Status: COMPLETED
Conditions: Dietary Fiber|Sports|Sports Nutrition|Microbiota|Nutrition Surveys
Interventions: DIETARY_SUPPLEMENT: Soluble dietary fiber with prebiotic properties|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant Therapy
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Acute Major Bleeding
Interventions: BIOLOGICAL: Beriplex® P/N (Kcentra)|BIOLOGICAL: Fresh frozen plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopurinol and Endothelial Function in Diabetic CAD Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus|Coronary Artery Disease
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of Mifepristone
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Mifepristone Oral Tablet [Korlym]|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GET FIT Prostate: A Randomized Controlled Exercise Trial
Status: COMPLETED
Conditions: Prostate Carcinoma
Interventions: OTHER: Resistance Training|OTHER: Stretching|OTHER: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiotherapy Treatment for Uterine Blood Flow Improved Dimensional Ultrasound Evaluated With Angiography
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Reproductive Technique Gimilio|OTHER: Placebo Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Carvedilol 12.5 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol 12.5 mg Tablets, single dose|DRUG: Coreg® 12.5 mg Tablets , single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Interaction Effects of Temperature and Ozone
Status: COMPLETED
Conditions: Exposure to Environmental Pollution, Non-occupational
Interventions: OTHER: Clean Air|OTHER: Ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SoundBite™ Crossing System Pivotal Peripheral CTO Crossing Study
Status: COMPLETED
Conditions: Chronic Total Occlusion of Arteries of the Extremities
Interventions: DEVICE: SoundBite™ Crossing System - Peripheral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DTPA (Diethylenetriaminepenta-acetate) Chelation for Symptoms After Gadolinium-assisted MRI Exposure
Status: ACTIVE_NOT_RECRUITING
Conditions: Gadolinium Deposition Disease
Interventions: DRUG: Calcium DTPA and Zinc DTPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab and Anlotinib Combined With Chemotherapy in Neoadjuvant Treatment of Resectable Esophageal Cancer
Status: COMPLETED
Conditions: Sintilimab and Anlotinib in Combination With Chemotherapy
Interventions: DRUG: Sintilimab and anlotinib in combination with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: ABX464
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy Adults
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: TBAJ-587|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of QAX576 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: QAX576|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Withania Somnifera: an Immunomodulator and Anti-inflammatory Agent for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Sensoril®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Inspiratory Muscle Training Protocols in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Inspiratory Muscle Training|Exercise Capacity
Interventions: OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Of 90mg Of GW274150 In Subjects Over 50 Years, Who Have Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GW274150
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RADIATION PROTECTion With a Pelvic Lead Shield and a Radiation Protection Cap for Operators Performing Coronary Angiography or Intervention
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: PROCEDURE: With Lead Shield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: microRNAs in the Diagnosis of Atherosclerotic Plaque Instability
Status: RECRUITING
Conditions: Atherosclerosis of Artery
Interventions: DIAGNOSTIC_TEST: blood microRNA|DIAGNOSTIC_TEST: plaque and intima microRNA|DIAGNOSTIC_TEST: histological examination of the plaque|DIAGNOSTIC_TEST: blood level trimethyl N-oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Efbemalenograstim Alfa Injection for Stage IIIB or IV NSCLC Recieving Moderate-risk Febrile Neutropenia (FN) Chemotherapy Regimen With Risk Factors
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Efgbemalenograstim alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Heparin-grafted Membrane for CRRT
Status: COMPLETED
Conditions: Acute Kidney Injury|Hemorrhage|Coagulopathy
Interventions: DEVICE: oXiris as first filter|DEVICE: M150 as first filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Clinical And Subclinical Effects on Arterial Stiffness of Bosentan in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Somatostatin Analogues in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Respiratory Tract Neoplasms|Thymic Neoplasms|Pancreatic Neoplasms|Gastrointestinal Neoplasms|Multiple Endocrine Neoplasia
Interventions: DRUG: Octreotide-LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacokinetic and Pharmacodynamic Properties of Insulin Icodec in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Icodec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subject Information and Consent Form F1J-US-HMCB Duloxetine Once-Daily Dosing Versus Placebo in Patients With Major Depression and Pain
Status: COMPLETED
Conditions: Depression|Pain
Interventions: DRUG: Duloxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Herceptin (Trastuzumab) and Xeloda (Capecitabine) in Patients With HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]|DRUG: trastuzumab [Herceptin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Preoperative Serum Cytokine Level and Lenght of Stay in Hospital, Postoperative Pain Intensity, Functional Status, Joint Position Sense and X Ray Findings
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: OTHER: Cytokine level
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: COVID|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: Convalescent plasma|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Multiple Myeloma|Histiocytic Neoplasms|Erdheim-Chester Disease|Rosai-Dorfman Disease
Interventions: DRUG: [68Ga]-Pentixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Antimicrobial Photodynamic Therapy and Minimal Intervention Associated With Deproteinization in Permanent Teeth With Molar Incisor Hypomineralization
Status: RECRUITING
Conditions: Hypomineralization Molar Incisor
Interventions: PROCEDURE: Antimicrobial PDT and Papacarie Deproteinization|PROCEDURE: Conventional caries treatment|PROCEDURE: Antimicrobial PDT and 5% NaOCl Deproteinization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Idarubicin Combined to Azacitidine in Int-2 or High Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: High Grade Myelodysplastic Syndrome Lesions
Interventions: DRUG: azacitidine and idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Piezocision-assisted Orthodontic Treatment in Adult Patients
Status: COMPLETED
Conditions: Tooth Overcrowding
Interventions: PROCEDURE: Orthodontic procedures (for both groups : Control group and Test group)|PROCEDURE: Piezo-assisted orthodontics (only the Test group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Status: RECRUITING
Conditions: Disorder of Consciousness
Interventions: OTHER: Use of "expressive" sounds|OTHER: Having benefited from a prognostic evaluation by event related potentials (without sound research methods, only neutral sounds)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Patch Healing vs. Secondary Intention Healing After Mohs Micrographic Surgery
Status: RECRUITING
Conditions: Skin Cancer|Basal Cell Carcinoma
Interventions: PROCEDURE: MMS + Autologous patch|PROCEDURE: MMS and secondary intention healing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: MW189|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biliary Fistula and Late Recurrence of Liver Hydatid Cyst: Role of Cysto-biliary Communication
Status: COMPLETED
Conditions: Liver Surgery
Interventions: PROCEDURE: laparoscopic partial cystectomy with omentoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Supraglottic Aspiration in Intubated and Mechanically Ventilated Patients: the "SUPRAtube" Device
Status: COMPLETED
Conditions: Aspiration Pneumonias
Interventions: DEVICE: Supratube|OTHER: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Thrombus Aspiration in Patients With STEMI
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: PROCEDURE: percutaneous coronary intervention (PCI)|DEVICE: thrombus aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: s086 Tablets in the Treatment of Mild to Moderate Essential Hypertension
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: Sacubatril Allisartan medoxomil|DRUG: Olmesartan Medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: PROCEDURE: Endovascular thrombectomy/thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of an Anti-pneumococcal Combined Vaccination in Acute Leukemia or Lymphoma
Status: RECRUITING
Conditions: Vaccine|Streptococcus Pneumoniae|Acute Myeloid Leukemia|Lymphoma, Non-Hodgkin
Interventions: DRUG: Prevenar13 Pneumo-23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Teclistamab|DRUG: Talquetamab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Placement in Neonatal Intubation
Status: COMPLETED
Conditions: Neonatal Respiratory Failure
Interventions: OTHER: Weight+6|OTHER: NTL+1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-response Evaluation of the Cellavita HD Product in Patients With Huntington's Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: BIOLOGICAL: Cellavita HD lower dose|BIOLOGICAL: Cellavita HD higher dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Big Data and Genomic Imaging for the Development of Biomarkers and Nanovector Drugs Innovative for Diagnosis and Therapy of Inflammatory Processes in Dementia
Status: COMPLETED
Conditions: Neurodegenerative Diseases
Interventions: RADIATION: Magnetic Resonance (MR) and positron emission tomograph (PET) imaging analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of NPT189 in Healthy Subjects
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: NPT189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Guideline-based Management of Type-2 Diabetes by Ayurvedic Practitioners in Nepal
Status: COMPLETED
Conditions: Diabetes|Type2Diabetes|Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: Clinical Guideline based Management|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infliximab Plus Intravenous Immunoglobulin for the Primary Treatment of Kawasaki Disease
Status: COMPLETED
Conditions: Kawasaki Disease
Interventions: DRUG: Infliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventional Radiology Liver Directed Therapies and Hypofractionated Image-Guided Radiation Therapy in Veteran and Non-Veteran, Non-surgical Hepatocellular Carcinoma Patients
Status: RECRUITING
Conditions: Liver Cancer
Interventions: OTHER: Quality of life questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AVERT Shock: Arginine Vasopressin During the Early Resuscitation of Traumatic Shock
Status: COMPLETED
Conditions: Traumatic Shock
Interventions: DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 99m Tc-ANNexin-V-128 Scintigraphy for the Identification of Complicated Carotid Atherosclerotic Plaques
Status: WITHDRAWN
Conditions: Carotid Atherosclerosis|Atherosclerotic Plaque
Interventions: OTHER: 99mTc-Annexin-V-128 uptake on scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Optimizing Parameters for Long-pulsed Nd:YAG Laser for Reducing Hair Shaft Diameter
Status: COMPLETED
Conditions: Androgenetic Alopecia|Hair Loss/Baldness
Interventions: DEVICE: Long-pulsed, 1064nm Nd-YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Cognitive and Functional Strength Training in Children With cp
Status: COMPLETED
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: functional strength training|OTHER: cognitive training|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD Patients
Interventions: DRUG: Symbicort|DRUG: Formoterol turbohaler|OTHER: Placebo for Symbicort pMDI|OTHER: Placebo for Formoterol Turbohaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Global Registry and Natural History Study for Mitochondrial Disorders
Status: RECRUITING
Conditions: Mitochondrial Diseases|Kearns-Sayre Syndrome|MIDD|SANDO|SCAE|NARP Syndrome|MELAS Syndrome|MERRF Syndrome|Coenzyme Q10 Deficiency|LHON|MNGIE|MIRAS|Barth Syndrome|MDS|Mitochondrial Myopathies|Leigh Syndrome|Pearson Syndrome|CPEO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the BOKS Before-school Physical Activity Program
Status: COMPLETED
Conditions: Overweight and Obesity|Affect|Physical Activity|Fitness
Interventions: BEHAVIORAL: BOKS: 2 day a week before-school physical activity program|BEHAVIORAL: BOKS: 3 day a week before-school physical activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticus
Status: COMPLETED
Conditions: Status Epilepticus|Convulsive Status EPILEPTICUS|Non Convulsive Status Epilepticus|Epilepsy
Interventions: DRUG: IV Ganaxolone active|DRUG: IV Placebo, non-active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do All Patients With Congenital Hip Dysplasia Corrected Operatively Need Physiotherapy
Status: UNKNOWN
Conditions: Developmental Dysplasia of the Hip
Interventions: OTHER: prescribed physiotherapy course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Alveolar Probe-based Confocal Laser Endomicroscopy Descriptors in Diffuse Parenchymal Lung Diseases
Status: UNKNOWN
Conditions: Diffuse Parenchymal Lung Diseases
Interventions: PROCEDURE: Bronchoscopy|PROCEDURE: Confocal microendoscopy|PROCEDURE: Biopsy sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Equine Facilitated CBT Group Therapy for Youth Anxiety
Status: TERMINATED
Conditions: Anxiety
Interventions: BEHAVIORAL: Augmented equine-facilitated CBT group program|BEHAVIORAL: TAU is equine-facilitated group therapy|OTHER: WLC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Tumescent for Surgical Management of Tenosynovitis.
Status: COMPLETED
Conditions: Tenosynovitis
Interventions: COMBINATION_PRODUCT: Tumescent Anesthesia|DRUG: Lidocaine|DEVICE: Pneumatic tourniquet|PROCEDURE: Open release of the tendon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficient Treatment for Posttraumatic Injury for Firefighters
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Insomnia|Nightmare
Interventions: BEHAVIORAL: Written Exposure Therapy (WET)|BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBTi)|BEHAVIORAL: Cognitive Behavioral Therapy for Nightmares (CBTn)|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I)
Status: UNKNOWN
Conditions: Growth Hormone Deficiency
Interventions: BIOLOGICAL: PEG-somatropin|BIOLOGICAL: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Single-Arm Pilot Study in Adult Allogeneic Hematopoietic Stem Cell Transplant Recipients With Transfusional Iron Overload
Status: COMPLETED
Conditions: Iron Overload
Interventions: DRUG: deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Neointimal Coverage of EES and BMS After Implantation in STEMI Patients by Optical Coherence Tomography
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Xience™ V stent (Abbott Vascular, Santa Clara, California, USA)|DEVICE: Multilink-Vision stent(Abbott Vascular, Santa Clara, California, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Muscle Atrophy
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Muscular Atrophy
Interventions: DIETARY_SUPPLEMENT: Dietary supplementation|DIETARY_SUPPLEMENT: Placebo supplement|BEHAVIORAL: Nutritional counselling|BEHAVIORAL: Feedback on physical activity level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Safety, Tolerability, Pharmacokinetics and Recommended Phase 2 Dose (RP2D) of Livmoniplimab (ABBV-151) as a Single Agent and in Combination With Budigalimab (ABBV-181) in Participants With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors Cancer
Interventions: DRUG: Livmoniplimab|DRUG: Budigalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Comparison Study of Menactra® in US Children
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection|Neisseria Meningitidis
Interventions: BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Conjugate|BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Conjugate|BIOLOGICAL: Menactra®: Meningococcal Polysaccharide Diphtheria Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of CPAP on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Refractory Arterial Hypertension
Interventions: DEVICE: CPAP|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Injections Into Uterosacral Ligaments During Robotic Assisted Total Hysterectomies
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Bipivacaine 0.5% with epinephrine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Study to Evaluate the Effect of BTI320 on Glycemic Control in Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: BTI320|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES
Status: TERMINATED
Conditions: Primary Tauopathies|Corticobasal Degeneration Syndrome|Frontotemporal Lobar Degeneration With Tau Inclusions|MAPT Mutation Carriers, Symptomatic|Traumatic Encephalopathy Syndrome|Nonfluent Aphasia, Progressive
Interventions: DRUG: BIIB092|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT: Early Rehabilitation Protocol vs. Usual Care in the Pediatric ICU for Children With Acute Brain Injury
Status: COMPLETED
Conditions: Pediatric Acute Neurologic Disease, Traumatic and Non-traumatic
Interventions: OTHER: Early Rehabilitation Protocol|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BG2109 in Chinese Subjects With Endometriosis
Status: RECRUITING
Conditions: Endometriosis|Moderate to Severe Endometriosis-associated Pain
Interventions: DRUG: BG2109 100mg|DRUG: BG2109 200mg|DRUG: ABT(E2 1 mg / NETA 0.5 mg)|DRUG: BG2109 100mg Placebo|DRUG: BG2109 200mg Placebo|DRUG: ABT Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Occlusal Dentinal Caries in Deciduous Molars
Status: COMPLETED
Conditions: Caries, Dental
Interventions: PROCEDURE: no caries removal|PROCEDURE: partial caries removal upto soft dentin|PROCEDURE: partial caries removal upto firm dentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous (IV) Patient Controlled Analgesic (PCA) With Ketorolac or Fentanyl Combined With Caudal Block for Postoperative Analgesia in Small Children Undergoing Intravesical Ureteroneocystostomy
Status: COMPLETED
Conditions: Ureteroneocystostomy
Interventions: DRUG: ketorolac, fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient-Assisted Compression - Impact on Image Quality and Workflow
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Patient-Assisted (PA) Breast Compression|DEVICE: Technologist-Controlled (TC) Breast Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Filling of the Urinary Bladder During Difficult Cesarean Section
Status: COMPLETED
Conditions: Urinary Tract Injury|Cesarean Section Complications
Interventions: PROCEDURE: Bladder Filling|PROCEDURE: Bladder deflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Telemetric Glucose Data Acquisition During Initiation of Insulin Pump Therapy
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Insulin-Dependent
Interventions: DEVICE: GlucoDYNAMIX™ intervention system|DEVICE: GlucoMON™ telemetry device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Obesity Hypoventilation Syndrome
Status: COMPLETED
Conditions: Obesity Hypoventilation Syndrome
Interventions: PROCEDURE: Blood test analysis in the clinical labs|PROCEDURE: Pneumologist consult to establish the diagnosis of OHS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Under the Nose Face Mask to Prevent Facial Pressure Ulcers During NIV for Acute Hypercapnic Respiratory Failure (AHRF)
Status: COMPLETED
Conditions: Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Under-the-nose facemask|DEVICE: Over-the-nose facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Urethral Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Non-alcoholic Fatty Liver Disease|Obesity
Interventions: DRUG: Amlexanox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study in Healthy Volunteers to Evaluate the Safety, Tolerability and Pharmacokinetics of AVLX-144
Status: COMPLETED
Conditions: Safety Issues|Tolerance
Interventions: DRUG: AVLX-144|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Empowerment: an Integrated Approach Driving Demand and Delivery of High Quality, Low-cost Postnatal Services in Kenya
Status: COMPLETED
Conditions: Maternal and Newborn Health
Interventions: BEHAVIORAL: Delivery of a Post-Partum Package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: Dapagliflozin in PRESERVED Ejection Fraction Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure With Preserved Systolic Function
Interventions: DRUG: Dapagliflozin 10Mg Oral Tablet|DRUG: Dapagliflozin matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Associated to Systemic Bevacizumab for the Treatment of Refractory Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Liver Metastasis Colon Cancer
Interventions: DEVICE: TACE+ systemic Bevacizumab|DRUG: FOLFIRI+Bevacizumab|DEVICE: TACE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of AB-205 in Adults With Lymphoma Undergoing High-Dose Therapy and Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Non-hodgkin Lymphoma
Interventions: BIOLOGICAL: AB-205
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pec Infiltration With Liposomal Bupivacaine for Breast Surgery
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of MEFP for Preschool Children With ADHD
Status: COMPLETED
Conditions: ADHD|Child, Only
Interventions: BEHAVIORAL: Metacognitive Executive Function Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Bimatoprost Solution in Increasing Eyelash Prominence in African Americans With Eyelash Hypotrichosis
Status: COMPLETED
Conditions: Hypotrichosis
Interventions: DRUG: bimatoprost ophthalmic 0.03% solution|DRUG: vehicle sterile solution (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: Paracetamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breast Milk Odor on Pain Response and Salivary Cortisol Level in Preterm Infants
Status: UNKNOWN
Conditions: Premature Infant|Pain|Breast Milk Odor
Interventions: OTHER: breast milk odor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Neuropathic Pain in Leprosy
Status: UNKNOWN
Conditions: Pain, Neuropathic|Leprosy|Leprosy Neuropathy|Amitriptyline
Interventions: DRUG: Amitriptyline|DRUG: Placebo oral capsule|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training on Glycemic Control in Individuals With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Inspiratory muscle training.|DEVICE: Placebo inspiratory muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Oprozomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Liposomal Docetaxel Formulation in Patients With Solid Tumors Who Have Failed Previous Therapies
Status: COMPLETED
Conditions: Solid Tumor|Breast Cancer|Ovarian Cancer|Pancreatic Cancer|Non-Small Cell Lung
Interventions: DRUG: ATI-1123 (active drug = docetaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRain Energy Activation With Ketones to Prevent Alzheimer's Disease
Status: RECRUITING
Conditions: MCI
Interventions: DIETARY_SUPPLEMENT: Active group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Samples and Clinical Data From Patients With Amyloid Diseases
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: GENETIC: clonality analysis|GENETIC: polymerase chain reaction|GENETIC: protein analysis|OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|PROCEDURE: fluorescence spectroscopy|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: mHealth + e-Navigator Stepped Care on ART Adherence in Latino MSM
Status: RECRUITING
Conditions: ART Adherence
Interventions: BEHAVIORAL: TXTXT|BEHAVIORAL: e-Navigation|BEHAVIORAL: Ecological Momentary Assessment (EMA) supported e-Navigation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT