pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
Status: COMPLETED
Conditions: Neuromuscular Block
Interventions: DRUG: Magnesium Sulfate|DRUG: Lidocaine|DRUG: Isotonic Solution|DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Diabetic Patients|Acute Myocardial Infarction
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple System Atrophy|Orthostatic Hypotension|Supine Hypertension
Interventions: DRUG: Trimethaphan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effect of 4th Generation Fluoroquinolones, Gatifloxacin and Moxifloxacin, on Epithelial Healing Following Photorefractive Keratectomy (PRK), A Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
Status: COMPLETED
Conditions: Epithelium, Corneal
Interventions: DRUG: Moxifloxacin|DRUG: Gatifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: cRCT to Improve Maternal Nutrition Service Delivery During ANC
Status: UNKNOWN
Conditions: Maternal Nutritional Deficiency During Childbirth
Interventions: OTHER: Strengthening coverage and quality of nutrition services during ANC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of RGn600 in Patients With Mild-to-moderate Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: RGn600|DEVICE: RGn600 Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Fluoride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Plus Antiretroviral Therapy for HIV-Infected Patients With Low CD4+ Counts (SILCAAT Study)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Proleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed
Status: TERMINATED
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Aldoxorubicin HCl|BIOLOGICAL: ETBX-011|BIOLOGICAL: ETBX-021|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-4000|BIOLOGICAL: GI-6207|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK for infusion|DRUG: Avelumab|DRUG: bevacizumab|DRUG: Capecitabine|DRUG: Cetuximab|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: nab-Paclitaxel|DRUG: Necitumumab|PROCEDURE: SBRT|BIOLOGICAL: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Assessment of Topical Anesthetic Effectiveness for Intravitreal Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: proparacaine HCL 0.5%|DRUG: proparacaine HCL 0.5% + 4% lidocaine solution|DRUG: 3.5% viscous lidocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound as Alternative to Radiation in Thoracic Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Thoracic Surgery|Ultrasonography
Interventions: DIAGNOSTIC_TEST: Lung Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Formulation and Efficacy of Exercise Prescription for Patients With Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: BEHAVIORAL: Moderate intensity exercise prescription|BEHAVIORAL: High intensity exercise prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase 3 Trial of Pemetrexed and Cisplatin Versus Gemcitabine and Cisplatin in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Carcinoma
Interventions: DRUG: pemetrexed|DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Efficacy of Formulation 609580 20 Versus Formulation 609209 in Children With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: OTHER: Formulation 609580 20|OTHER: Formulation 609209 (Lipikar Baume)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exten(d) Supplementation on Training Ability in Recreational Runners
Status: COMPLETED
Conditions: Joint Pain|Knee Inflammation|Biomechanical; Lesion
Interventions: DIETARY_SUPPLEMENT: Polyherbal Exten(d) vs Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Cycloergometric Physiotherapy in Critically Ill Patients With Invasive Mechanical Ventilation
Status: UNKNOWN
Conditions: Weakness
Interventions: PROCEDURE: Cycle ergometer physiotherapy|PROCEDURE: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Docetaxel & Bevacizumab +/- Trastuzumab in First-Line Treatment of Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Parkinson's Disease Treatment by hiPSCs Derived Dopaminergic Neural Precursor Cells
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease
Interventions: OTHER: hiPSC-DAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Health Benefits of Basis™ Among Elderly Subjects.
Status: COMPLETED
Conditions: Safety: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Basis 250|DIETARY_SUPPLEMENT: Basis 500|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Modified Trabeculectomy With an ESST Versus Conventional SST for Management of Primary Open Angle Glaucoma
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma
Interventions: PROCEDURE: SST in group (A)|PROCEDURE: trabeculectomy with ESST in group (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of SK-MS10 in Subjects With Acute and Chronic Gastritis
Status: COMPLETED
Conditions: Erosive Gastritis
Interventions: DRUG: Placebo|DRUG: SK-MS10|DRUG: SK-MS10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Deep Carious Lesions in Adults
Status: UNKNOWN
Conditions: Caries|Reversible Pulpitis
Interventions: PROCEDURE: Selective caries excavation|PROCEDURE: Non selective caries excavation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lasmiditan When Given With Sumatriptan in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lasmiditan|DRUG: Sumatriptan|DRUG: Placebo for Lasmiditan|DRUG: Placebo for Sumatriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccination of Prostate Cancer Patients With MUC-2-KLH Conjugate Plus the Immunological Adjuvant QS21
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: MUC-2-KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic IIeocecus-Sparing Right Hemicolectomy for Cancer of the Hepatic Flexure and Proximal Transverse Colon
Status: COMPLETED
Conditions: Hepatic Flexure Colon Cancer|Proximal Transverse Colon Cancer
Interventions: PROCEDURE: laparoscopic ileocecus-sparing right hemicolectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access to Veliparib
Status: NO_LONGER_AVAILABLE
Conditions: Solid Tumors With Documented BRCA, BARD, or PALB or Other Acceptable DNA Mutations or Anomalies That Are Scientifically Sound|Triple Negative Breast Cancer (TNBC)|High Grade Serous Ovarian Cancer|Patients Requiring Veliparib Suspension Formulation
Interventions: DRUG: Veliparib
Study Type: EXPANDED_ACCESS
Clinical trial: Methylphenidate-Duloxetine Combinations for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Methylphenidate|DRUG: Placebo|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of XmAb®5574 in Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: XmAb5574
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Families' Experiences of Paediatric ICC Diagnosis
Status: UNKNOWN
Conditions: Inherited Cardiac Conditions
Interventions: BEHAVIORAL: Initial Screening Process|BEHAVIORAL: Information and Informed Consent|BEHAVIORAL: Interview|BEHAVIORAL: Validated Questionnaires|BEHAVIORAL: Debrief
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Prospective Randomized Trial on Comparison of Standard- Carbon Dioxide Pressure Pneumoperitoneum Insufflators Versus AirSeal
Status: COMPLETED
Conditions: Colorectal Disorders|Hernia|Incidence for Cholecystectomy
Interventions: PROCEDURE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Gemfibrozil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Frown Lines
Interventions: DRUG: IncobotulinumtoxinA (Xeomin) (20 Units)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Treatment of Food Addiction
Status: RECRUITING
Conditions: Overweight|Obesity
Interventions: DEVICE: Active stimulation with Diadem ultrasonic transducer array|DEVICE: Sham stimulation with Diadem ultrasonic transducer array
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children
Status: COMPLETED
Conditions: Pain|Sickle Cell Disease
Interventions: DRUG: Fentanyl Citrate|DRUG: Morphine sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leveraging Community Health Workers to Combat COVID-19 and Mental Health Misinformation in Haiti, Malawi, and Rwanda
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health|COVID-19|Misinformation
Interventions: BEHAVIORAL: Card-Sorting Activity (Pre-intervention design)|BEHAVIORAL: SMS Crafting (Pre-intervention design)|BEHAVIORAL: SMS Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open, Single Center, Randomized Controlled Clinical Study of UCB (Cord Blood) in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: UCB (Cord Blood) Microtransplantation in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Interventions: COMBINATION_PRODUCT: Basic chemotherapy + UCB transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Abuse|Alcohol Dependence|Craving
Interventions: DEVICE: Real TBS to the vmPFC|DEVICE: Sham TBS to the vmPFC|DEVICE: Real TBS to the dlPFC|DEVICE: Sham TBS to the dlPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise and Protein During Weight Loss
Status: COMPLETED
Conditions: Weight Loss|Starvation
Interventions: OTHER: Caloric Restriction|DIETARY_SUPPLEMENT: Post-Exercise Protein|OTHER: Energy Balance|DIETARY_SUPPLEMENT: Post-Exercise Carbohydrate|DIETARY_SUPPLEMENT: Calcium and Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ventricular Tachycardia Ablation in LVAD Patients
Status: NOT_YET_RECRUITING
Conditions: Ventricular Tachycardia|End-stage Heart Failure|Ventricular Arrythmia|LVAD (Left Ventricular Assist Device)
Interventions: OTHER: Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of VM-1500A-LAI Single and Multiple Ascending Doses in Healthy Subjects
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: VM-1500A-LAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ultrasonographic Evaluation of the Right Common Femoral Vein Diameter for Predicting Spinal Anesthesia-induced Hypotension in Elderly Patients
Status: COMPLETED
Conditions: Spinal Anesthesia-induced Hypotension
Interventions: DIAGNOSTIC_TEST: preoperative ultrasonographic evaluation of right common femoral vein diameter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tele-homecare Service for Diabetic Foot Patients (Risk 0, Risk 1 and Risk 2 Level): Testing and Validation of Dedicated APPs and Artificial Intelligence Solutions
Status: NOT_YET_RECRUITING
Conditions: APP Elaborates Data Input From the Patient With Foot Ulcer
Interventions: DEVICE: Lifestyle APP and Artificial Intelligence solutions validation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Red Raspberry Consumption on Fasting Oxidative Stress Biomarkers
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: individually quick frozen red raspberries|DIETARY_SUPPLEMENT: individually quick frozen red raspberries|DIETARY_SUPPLEMENT: individually quick frozen red raspberries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Xylitol for Otitis Media
Status: WITHDRAWN
Conditions: Otitis Media With Effusion
Interventions: DRUG: Intranasal xylitol spray|OTHER: Intranasal saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Adenosquamous Carcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation|Endometrial Serous Adenocarcinoma|Stage III Uterine Corpus Cancer
Interventions: DRUG: Doxorubicin Hydrochloride|DRUG: Cisplatin|BIOLOGICAL: Filgrastim|BIOLOGICAL: Pegfilgrastim|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Assisted Systems Change for Suicide Prevention
Status: COMPLETED
Conditions: Suicide|Suicide, Attempted
Interventions: BEHAVIORAL: In-person TASCS|BEHAVIORAL: Telehealth TASCS|BEHAVIORAL: Self-administered TASCS|BEHAVIORAL: Follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Ultra-high Dose Methylcobalamin for ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: methylcobalamin|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Hypertension in the Very Elderly Trial (HYVET)
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Indapamide SR 1.5mg; Perindopril 2-4mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Cognitive Dietary Restraint on Perceived Stress, Appetite Sensations, Food Cravings During Energy Restriction
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: Energy restriction plus CDR|BEHAVIORAL: Energy restriction without CDR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of a Non Electric Infant Warmer for Prevention and Treatment of Hypothermia in Rwanda
Status: UNKNOWN
Conditions: Hypothermia Neonatal
Interventions: DEVICE: Non-Electric Infant Warmer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Laryngopharyngeal Reflux
Interventions: DIAGNOSTIC_TEST: Reflux Band® Upper Esophageal Sphincter (UES) Assist Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Motexafin Gadolinium (MGd) in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Motexafin Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moxetumomab Pasudotox for Advanced Hairy Cell Leukemia
Status: COMPLETED
Conditions: Leukemia, Hairy Cell
Interventions: DRUG: Moxetumomab pasudotox|DRUG: IV Bag Protectant for Moxetumomab pasudotox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovary Syndrome|Obstructive Sleep Apnea
Interventions: DRUG: Depot Lupron followed by estrogen plus placebo|DRUG: Depot Lupron followed by progesterone plus placebo.|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunologic Response to Inactivated Vaccine for Novel H1N1 Virus
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated H1N1 vaccine|BIOLOGICAL: Inactivated H1N1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RO4929097 in Treating Patients With Recurrent Invasive Gliomas
Status: TERMINATED
Conditions: Adult Anaplastic Oligodendroglioma|Adult Brain Stem Glioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Recurrent Adult Brain Tumor
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|PROCEDURE: therapeutic conventional surgery|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
Status: COMPLETED
Conditions: Overweight and Obesity|PreDiabetes|Insulin Resistance
Interventions: DEVICE: CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Doxycycline on Cardiac Remodelling in STEMI Patients
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction|Anterior Wall Myocardial Infarction|Heart Failure|Remodeling, Ventricular
Interventions: DRUG: Doxycycline 100Mg Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Testosteron 250mg injection|DRUG: Testosterone 50mg transdermal application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development & Pilot RCT of an Online Peer Support Program for Family Caregivers of Ventilator-Assisted Individuals
Status: UNKNOWN
Conditions: Social Support|Affect|Ventilators, Mechanical
Interventions: BEHAVIORAL: Online Peer Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB)
Status: TERMINATED
Conditions: Myelodysplastic and Myeloproliferative Disorders|Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelogenous Leukemia|Multiple Myeloma|Plasma Cell Dyscrasia|Lymphoproliferative Disorders|Hematologic Diseases
Interventions: DRUG: Campath|DRUG: Busulfan|DRUG: Fludarabine|PROCEDURE: Hematopoietic stem cell infusion|DRUG: FK-506
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Minocycline for Helicobacter Pylori Rescue Treatment
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Bismuth Potassium Citrate|DRUG: Tetracycline,Metronidazole|DRUG: Minocycline,Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Effectiveness of Pridopidine Compared to Placebo in the Treatment of Levodopa-Induced Dyskinesia in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Pridopidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Birds With One Stone
Status: COMPLETED
Conditions: Uterine Cervical Cancer|Uterine Cervix Cancer|Uterine Cervical Neoplasm|Colorectal Neoplasms|Colorectal Cancer|Colorectal Carcinoma|Mass Screening|Early Detection of Cancer
Interventions: BEHAVIORAL: Screening status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Interventions to Improve Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: OTHER: Mailed fecal occult blood tests|OTHER: Mailed fecal immunochemical tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hydrocodone/Acetaminophen for Acute Pain Following Third Molar Tooth Extraction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ABT-712 Extended-release|DRUG: Hydrocodone/Acetaminophen Immediate-release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional MRI Evaluation of Brain Response to Visual Food Stimulation in Morbidly Obese Patients Before and After Bariatric Surgery
Status: COMPLETED
Conditions: Morbid Obesity|Satiety
Interventions: PROCEDURE: fMRI imaging following visual stimulation of food and non-food images
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Protocolized Post-Extubation Respiratory Support Study
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Acute Respiratory Failure|Intubation Complication
Interventions: OTHER: Protocolized post-extubation respiratory support|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Efficacy Of Eplerenone Compared With Losartan For The Treatment Of Patients With Mild To Moderate Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: eplerenone|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Terazosin for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Terazosin 5 MG|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Tumors|Kidney Cancers|Small Cell Lung Cancers|Pheochromocytoma/Paragangliomas|Gastrointestinal Neuroendocrine Tumors|Somatostatin Receptor Positive
Interventions: DRUG: 68Ga-DOTATATE|DRUG: [203Pb]VMT-alpha-NET|DRUG: [212Pb]VMT-alpha-NET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Paclitaxel Plus Carboplatin Followed by Gemcitabine Plus Carboplatin for Patients With Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: gemcitabine|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INNOVATEDIGNITY: Co-designing Digital Health Technologies With Older People in Homecare Settings.
Status: UNKNOWN
Conditions: Dignity|Old Age; Debility|Healthy Aging|Digital Technology
Interventions: OTHER: No Interventions. Participants will be using their everyday digital health technologies.|OTHER: In depth Interviews|OTHER: Focus Group Discussions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Osteoarthritis|Metal Ion Levels
Interventions: DEVICE: Coated Total Knee Arthroplasty|DEVICE: Standard Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conbercept vs Panretinal Photocoagulation for the Management of Proliferative Diabetic Retinopathy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: intravitreal injection of conbercept|DEVICE: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: IHL-675A|DRUG: Cannabidiol|DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, PD, and Immunogenicity of Single and Multiple Ascending Intravenous Doses of FR104
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Complication of Transplant
Interventions: DRUG: FR104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: DRUG: Bupropion|DRUG: Zonisamide|DRUG: Placebo bupropion|DRUG: Placebo zonisamide|OTHER: E-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Frozen Section Pathology to Guide Surgical Treatment for Lung Adenocarcinoma (ECTOP-1015)
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Surgical Procedure, Unspecified|Pathology
Interventions: PROCEDURE: Surgical resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Use of Oseltamivir for the Treatment of Influenza in Adults
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin Lymphoma
Status: COMPLETED
Conditions: Brain Tumors|Central Nervous System Tumors|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Head and Neck Cancer|Lymphoma|Nausea|Vomiting|Neuroblastoma|Ovarian Cancer|Sarcoma
Interventions: PROCEDURE: electroacupuncture therapy|PROCEDURE: sham intervention|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Intraoperative Navigation-assisted Channel Screw Technique in the Treatment of Pelvic Fractures
Status: NOT_YET_RECRUITING
Conditions: Pelvic Fracture
Interventions: PROCEDURE: Intraoperative navigation combined with Catheter screw technique|PROCEDURE: Open reduction and internal fixation with steel plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chinese Herbal Medicine to Prevent and Treat COVID-19 Close Contacts
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Chinese herbal medicine is in the form of granules (9 g/sachet), which is comprised of ten medicinal herbs.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adherence and Acceptability of a Remote, Home-based, Pre-surgery Programme for Patients Undergoing Abdominal Aortic Aneurysm Surgery
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: BEHAVIORAL: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of TissueGene-C Mixed With Fibrin-glue for the Patients With Degenerative Arthritis
Status: COMPLETED
Conditions: Degenerative Arthritis
Interventions: BIOLOGICAL: TissueGene-C (Low dose)|BIOLOGICAL: TissueGene-C (High dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Task-based Credentialing for Medical Officers in Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia|Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care
Interventions: OTHER: delivery of the spinal anesthetic by a trained medical officer|OTHER: delivery of spinal anesthetic by a consultant anesthetist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye Drop
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Carboxymethylcellulose sodium and Glycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preventing Ovarian Cancer Through Oportunistic Salpingectomy at the Time of Colorectal Surgery
Status: RECRUITING
Conditions: Salpingectomy|Colorectal Surgery
Interventions: PROCEDURE: Bilateral salpingectomy|PROCEDURE: Colorectal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: S-217622
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059)
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: pembrolizumab|DRUG: cisplatin|DRUG: 5-FU|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 in Older Athletes Treated With Statin Medications
Status: COMPLETED
Conditions: Muscle Weakness|Myalgia|Side Effects of Statins
Interventions: DRUG: Coenzyme q 10|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supportive Clinic for Patients Living With Advanced and Metastatic Cancers
Status: NOT_YET_RECRUITING
Conditions: Cancer|Physical Symptom Distress
Interventions: BEHAVIORAL: Supportive clinic|BEHAVIORAL: Control: Self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis|Tuberculosis Diagnosis|Covid-19|HIV
Interventions: DIAGNOSTIC_TEST: Accuracy of CAD4TB and Afinion CRP assay for pulmonary TB|DIAGNOSTIC_TEST: CAD4COVID+WBC and COVID-19 RDT for SARS-CoV-2 infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis
Status: WITHDRAWN
Conditions: Osteomyelitis
Interventions: DRUG: Dalbavancin|DRUG: cefazolin, nafcillin, oxacillin or vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: ifosfamide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: Sm-EDTMP (low dose)|RADIATION: sm-EDTMP (higher dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Silicone Hydrogel Lenses Over a One Month Period
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon A contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cornea Donor Study
Status: COMPLETED
Conditions: Corneal Disease|Fuch's Dystrophy|Pseudophakic Corneal Edema
Interventions: OTHER: corneas assigned by donor age group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acute Effects of Sitting and Physical Activity on Brain Health
Status: COMPLETED
Conditions: Healthy Adults
Interventions: BEHAVIORAL: Prolonged sitting with social break|BEHAVIORAL: Prolonged sitting with walk break|BEHAVIORAL: Prolonged sitting with simple resistance activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NeoMET Study in Neoadjuvant Treatment of Breast Cancer
Status: TERMINATED
Conditions: pCR Rate|BCT Rate|Safety
Interventions: DRUG: Metformin|DRUG: Docetaxel|DRUG: Epirubicin|DRUG: cyclophosphomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Effectiveness of Patients on Break Anterior Cruciate Ligament.
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: Dry needling|OTHER: Stability and propioception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPX-351 Salvage Therapy Followed by Haplo-Cord Transplant for Relapsed/Refractory Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Leukemia, Relapsed Adult Acute Myeloid|Myelodysplastic Syndromes, Previously Treated
Interventions: DRUG: CPX-351|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Rabbit Anti-Human T-Lymphocyte Globulin|BIOLOGICAL: Haplo-Cord Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuronal Ceroid-Lipofuscinoses|Neuronal Ceroid Lipofuscinosis CLN2|Spinocerebellar Ataxia, Autosomal Recessive 7
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of SII Yellow Fever Vaccine to Compare Safety and Immunogenicity With STAMARIL
Status: RECRUITING
Conditions: Yellow Fever
Interventions: BIOLOGICAL: STAMARIL|BIOLOGICAL: SII-YFV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Games & Well-Being Study
Status: COMPLETED
Conditions: Attentional Processing|Adolescent Behavior
Interventions: OTHER: Attention Training Intervention Game|OTHER: Prosocial Training Intervention Game|OTHER: Control for Attention Intervention|OTHER: Control for Prosocial Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Ticagrelor and Aspirin for the Prevention of Cardiovascular Events After Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2b, Open-label, Multicenter, Rollover Study to Assess Antiviral Activity and Safety of Long-acting (LA) Cabotegravir (CAB) Plus LA Rilpivirine (RPV), Administered Every 2 Months (Q2M), in Human Immunodeficiency Virus (HIV)-Positive Participants From the LATTE Study
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CAB LA|DRUG: RPV LA|DRUG: RPV|DRUG: DTG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone vs. Nintedanib for Fibrotic Lung Disease After Coronavirus Disease-19 Pneumonia
Status: UNKNOWN
Conditions: Novel Coronavirus-induced Lung Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone Metastasis
Status: COMPLETED
Conditions: Prostate Cancer With Bone Metastasis
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Celecoxib|DRUG: Ibuprofen|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ADH-1 in Combination With Normothermic Isolated Limb Infusion of Melphalan
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: ADH-1|DRUG: melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Status: RECRUITING
Conditions: Single Ventricle Heart Disease
Interventions: DRUG: Udenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of OPD5 Followed by Autologous Stem Cell Transplant for Patients With Relapsed Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Relapse Multiple Myeloma|Multiple Myeloma
Interventions: DRUG: OPD5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BENEFIT Study (Betaferon® / Betaseron® in Newly Emerging Multiple Sclerosis for Initial Treatment) and BENEFIT Follow-up Study
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (Betaseron, BAY86-5046)|DRUG: Interferon beta-1b (Betaseron, BAY86-5046)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Man Study: Safety and Efficacy of INC-1 Bare Metal Stent in the Novo Coronary Lesions.
Status: WITHDRAWN
Conditions: Stents|Coronary Artery Disease|Angioplasty|Humans|Coronary Angiography|Angioplasty, Balloon, Coronary|Treatment Outcome
Interventions: DEVICE: Stent INC1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT