pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
Status: RECRUITING
Conditions: Kidney Diseases|Cardiometabolic Risk Factors
Interventions: BEHAVIORAL: ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD)
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorders
Interventions: DRUG: Tetrahydrocannabinol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination Course in Primed Children and Age-matched Unprimed Children With Pneumococcal Vaccine GSK1024850A
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Orthopaedic Smoking Cessation Education on Cigarette Abstinence Self-Efficacy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: General Smoking Cessation Discussion|BEHAVIORAL: Orthopaedic Related Smoking Cessation Discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)
Status: RECRUITING
Conditions: Enterostomy
Interventions: OTHER: mucous fistula refeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work Environment
Status: COMPLETED
Conditions: MDD
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Bone Microarchitecture With HR-pQCT of Patients With Chronic Kidney Disease (CKD) Candidates for Renal Transplantation
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Hyperparathyroidism, Secondary
Interventions: DEVICE: HR-pQCT|DEVICE: DEXA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 3-D Endoanal Ultrasound: Normative Anatomy of the Anal Sphincter in Nulliparous Females
Status: COMPLETED
Conditions: Normal (no Known Injury) Anal Sphincter Female Anatomy
Interventions: PROCEDURE: 3-D Endoanal Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy.
Status: UNKNOWN
Conditions: Appendicitis
Interventions: PROCEDURE: saline-gentamicin irrigation|PROCEDURE: saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy of Resection Cavity For Single Brain Metastasis Versus Whole-Brain Radiotherapy After Resection
Status: UNKNOWN
Conditions: Brain Metastases
Interventions: RADIATION: stereotactic body radiotherapy (SBRT)|RADIATION: Whole-Brain Radiotherapy (WBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Biomarkers in Patients With Single Ventricle Physiology
Status: COMPLETED
Conditions: Hypoplastic Left Heart|Congenital Heart Disease|Cyanotic Congenital Heart Disease|Cardiac Disease
Interventions: PROCEDURE: Norwood Palliation / DKS / Damus-Kaye-Stansel procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of TPF Induction Chemotherapy for Borderline-resectable Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel+Cisplatin+5fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microarchitecture of the Augmented Bone Following Sinus Elevation
Status: COMPLETED
Conditions: Alveolar Bone Loss|Sinus Pneumatization|Edentulous; Alveolar Process, Atrophy
Interventions: PROCEDURE: sinus floor elevation|PROCEDURE: bone core biopsy|DEVICE: dental implant placement|DIAGNOSTIC_TEST: Cone Beam Computed Tomography scans (CBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12 Weeks Orienteering Program Exercise on Older Adults
Status: ENROLLING_BY_INVITATION
Conditions: Community-dwelling Older Adults
Interventions: OTHER: Orienteering exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharynx Cancer|Pain|Swallowing Disorder|Quality of Life|Saliva Altered|Human Papilloma Virus
Interventions: PROCEDURE: Primary Trans Oral Robotic Surgery (TORS)|RADIATION: Radio(chemo)therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy
Status: COMPLETED
Conditions: Germ Cell Tumors|Hepatic Cancer|Neuroblastoma|Osteosarcoma|Rhabdomyosarcoma
Interventions: DRUG: Recombinant Human Thrombopoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Giredestrant-matched Placebo|DRUG: Letrozole|DRUG: Letrozole-matched Placebo|DRUG: Palbociclib|DRUG: LHRH Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Hemodialysis Without Systemic Heparinization : a Randomized Study
Status: COMPLETED
Conditions: Contra-Indication to the Use of Low Molecular Weight Heparin
Interventions: PROCEDURE: Dialysis without systemic heparinization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk
Status: RECRUITING
Conditions: Plaque, Atherosclerotic|Carotid Artery Plaque|Carotid Stenosis
Interventions: DIAGNOSTIC_TEST: Acoustic Radiation Force Impulse (ARFI) ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma
Status: COMPLETED
Conditions: SARS-Associated Coronavirus|Covid19|SARS-CoV Infection
Interventions: BIOLOGICAL: Convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cocoa Extract-enriched Meals and Cardiovascular Risk in Older Population
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Cocoa extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
Status: COMPLETED
Conditions: Use; Tobacco, Harmful|Alcohol Abuse|Drug Abuse
Interventions: BEHAVIORAL: iMET|BEHAVIORAL: iMET/TE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of MAFLD in Patients With Type 2 Diabetes in Jiangsu Province of China
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus in Remission|Metabolic Associated Fatty Liver Disease
Interventions: PROCEDURE: Ultrasound attenuation parameter measurement, fasting blood glucose and fasting insulin determination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Safety and Pharmacokinetics in Healthy Volunteers and Safety, Tolerability and Antiviral Activity of VM-1500 in Patients With Human Immunodeficiency Virus-1 Infection
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: VM-1500/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Perceived Outcome After Total Wrist Arthroplasty With a New Total Wrist Arthroplasty Implant
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Osteoarthritis
Interventions: DEVICE: total wrist arthroplasty, Trimed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Modified FOLFOX6 Plus or Minus Sorafenib in Stage IV Metastatic Colorectal Carcinoma (mCRC) Subjects
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006) + mFOLFOX6 (5-FU, levo-leucovorin, oxaliplatin)|DRUG: Matching placebo + mFOLFOX6 (5-FU, levo-leucovorin, oxaliplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Lemborexant 10 mg|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrative Proteomic Characterization of Pancreatic Ductal Adenocarcinoma
Status: UNKNOWN
Conditions: Tumor Tissues and Non-tumor Tissues From PDAC Patients Were Used for Genomic and Transcriptome Sequencing Analysis and Proteomics and Phosphorylated Proteomics
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Liraglutide on the Reward Properties of Food: an fMRI Study on Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Human Male Subjects
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients
Status: COMPLETED
Conditions: Primary Mitochondrial Myopathy
Interventions: DRUG: Mavodelpar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Cognitive behavioral interventions|BEHAVIORAL: Attention control education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Automated Control of End-tidal Volatile Anesthetic Concentration
Status: COMPLETED
Conditions: Delayed Recovery From Anesthesia
Interventions: DRUG: Desflurane|DRUG: Sevoflurane|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA)
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: inhaled nitric oxide (iNO)|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Pharmacotherapy for Cannabis Dependence
Status: COMPLETED
Conditions: Cannabis Dependence
Interventions: DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia
Status: COMPLETED
Conditions: Oromandibular Dystonia|Cranial Dystonia
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Childhood Asthma Research and Education (CARE) Network Trial - Montelukast or Azithromycin for Reduction of Inhaled Corticosteroids in Childhood Asthma (MARS)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Budesonide + Salmeterol + Azithromycin|DRUG: Budesonide + Salmeterol + Montelukast|DRUG: Budesonide + Salmeterol + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia
Status: COMPLETED
Conditions: Invasive Pulmonary Aspergillosis|Lymphoblastic Leukaemia|Myeloblastic Leukaemia|Lymphoblastic Leukemia|Myeloblastic Leukemia
Interventions: DRUG: AMPHOTERICIN B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HLAB-002 of ANS-6637 for Alcohol Use Disorder
Status: TERMINATED
Conditions: Alcohol Use Disorder
Interventions: DRUG: ANS-6637|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Diagnosis and Prognosis Recognition of Imaging and Biomarkers in Mild to Moderate Traumatic Brain Injury
Status: RECRUITING
Conditions: MTBI - Mild Traumatic Brain Injury|Moderate Traumatic Brain Injury
Interventions: DEVICE: MRI, CT, and serum biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Benzoyl peroxide gel|DRUG: Clindamycin gel|DRUG: Tazarotene cream|DRUG: Vehicle gel|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Study of IL-2 Dose Frequency on Regulatory T Cells in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section
Status: RECRUITING
Conditions: Scar|Cesarean Section; Dehiscence
Interventions: OTHER: Scar Deactivation Surface Release Technique protocol|OTHER: Scar Infiltration with 0.25-1% Lidocaine|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block With Plain Bupivacaine Versus Wound Infiltration With Exparel for Postoperative Pain Management
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Plain bupivacaine|DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Mometasone Furoate/Formoterol Fumarate Inhalation Combination in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mometasone furoate|DRUG: Formoterol fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema
Status: WITHDRAWN
Conditions: Hereditary Angioedema
Interventions: DRUG: GNR-038, 50 МЕ/ kg|DRUG: GNR-038, 100 МЕ/ kg|DRUG: Berinert®, 20 МЕ/ kg|DRUG: Placebo|DRUG: GNR-038. The dose will be selected according to results of stage 1 clinical trial.|DRUG: Berinert®, 20 МЕ/ kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Control Treatment for Post Traumatic Stress Disorder ׂ(PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Personalized Attention control training (ACT)|BEHAVIORAL: Non-personalized Attention control training (ACT)|BEHAVIORAL: Control training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Transcutaneous Auricular Vagus Nerve Stimulation to Treat Acute Alcohol Withdrawal
Status: WITHDRAWN
Conditions: Alcohol Withdrawal|Alcohol Use Disorder
Interventions: DEVICE: Transcutaneous Nerve Stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Transforaminal Injection of Steroids Guided by Ultrasound
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: PROCEDURE: SNR steroid (dexamethasone) injection|PROCEDURE: CTF steroid (dexamethasone) injection|DRUG: Dexamethasone|DEVICE: Ultrasound|RADIATION: C arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology
Status: UNKNOWN
Conditions: Thyroid Nodule|Thyroid Cancer
Interventions: PROCEDURE: FNA biopsy for thyroid nodule(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study 2: Learning New Words From Overhearing in Children With Autism Spectrum Disorder (ASD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Overheard Speech|BEHAVIORAL: Addressed Speech
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Dimensional Alveolar Bone Changes in Immediate Post Extraction Implant Placement
Status: COMPLETED
Conditions: Immediate Implant With Loading
Interventions: PROCEDURE: immediate implant placement with or without loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Anabolic Effect of Testosterone on Pelvic Floor Muscles
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence|Menopause
Interventions: DRUG: Testosterone cypionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Anesthetics on Clinical Outcome in Mitral and Aortic Valve Replacement in Adults
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Aortic Valve Insufficiency
Interventions: DRUG: Propofol|DRUG: Isoflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study, Combination, Immunologic Study of LTX-315 as Adjunct to GV1001 in Patients Following Curative Surgery for Carcinoma
Status: COMPLETED
Conditions: Carcinoma
Interventions: DRUG: LTX-315
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of PD-1 Inhibitors in Patients With Liver Transplant
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Transplantation
Interventions: DRUG: JS001(PD-1 inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Surveillance for Brentuximab Vedotin Intravenous Infusion "Relapsed or Refractory CD30-positive Peripheral T Cell Lymphoma or Pediatric Hodgkin Lymphoma"
Status: COMPLETED
Conditions: Peripheral T Cell Lymphoma|Pediatric Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin (Genetical Recombination)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GLIMEPIRIDE|DRUG: METFORMIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Exercise Program for Frail Older Adults
Status: NOT_YET_RECRUITING
Conditions: Frailty
Interventions: BEHAVIORAL: ACTIVE-AGE@home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autobiographical Memory Flexibility Training (MemFlex) for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Memory Flexibility training (MemFlex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Alveolar Rhabdomyosarcoma|Recurrent Ewing Sarcoma|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Refractory Alveolar Rhabdomyosarcoma|Refractory Ewing Sarcoma|Refractory Lymphoma|Refractory Malignant Solid Neoplasm
Interventions: DRUG: Elimusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab or Nivolumab in Treating Patients With Relapsed Hematologic Malignancies After Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient|Myeloproliferative Neoplasm|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Hematologic Malignancy|Recurrent Hodgkin Lymphoma|Recurrent Myelodysplastic Syndrome|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise, Acupuncture and Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia|Juvenile
Interventions: PROCEDURE: exercise training|PROCEDURE: acupuncture|PROCEDURE: Exercise, Acupuncture and Fibromyalgia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Selective Intra-arterial Injection of PRRT in Neuroendocrine Tumor Patients With Liver Metastases
Status: TERMINATED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: [90]Y-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Efficacy and Safety of Using Adjunctive Ibuprofen for XDR-TB Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Ibuprofen|DRUG: Standard of Care TB treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Laparoendoscopic Single Site Adnexal Surgery for Benign Ovarian and Tubal Disease
Status: UNKNOWN
Conditions: Benign Ovarian or Tubal Disease
Interventions: PROCEDURE: Single-port laparoscopic adnexal surgery|PROCEDURE: Three-port laparoscopic adnexal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Vaporous Hyperoxia Therapy (VHT) in the Treatment of Chronic Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Vaporous Hyperoxia Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts
Status: COMPLETED
Conditions: AIDS Dementia Complex|HIV Infections
Interventions: DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure Chamber Trial With Cat Immunotherapy
Status: COMPLETED
Conditions: Cat Allergy
Interventions: BIOLOGICAL: Specific allergen immunotherapy (placebo)|BIOLOGICAL: Specific allergen immunotherapy|BIOLOGICAL: Specific allergen immunotherapy|BIOLOGICAL: Specific allergen immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical Trial
Status: COMPLETED
Conditions: Multiple System Atrophy
Interventions: DRUG: 1) Inosine 5'-monophosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The HistoSonics Edison™ System for Treatment of Pancreatic Adenocarcinoma Using Histotripsy
Status: NOT_YET_RECRUITING
Conditions: Pancreas Cancer|Adenocarcinoma of the Pancreas|Pancreatic Cancer|Tumor of Pancreas
Interventions: DEVICE: HistoSonics Edison™ System for the treatment of pancreatic adenocarcinoma using histotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
Status: COMPLETED
Conditions: Refractive Error|Myopia|Myopic Astigmatism
Interventions: DEVICE: Nelfilcon A contact lenses|DEVICE: Etafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating Intravenous Melphalan With Autologous Whole Blood Stem Cell Transplantation Over Three Cycles In Patients With Castration-Resistant Prostate Cancer (MEL-CAP)
Status: TERMINATED
Conditions: Castrate Resistant Prostate Cancer
Interventions: DRUG: Melphalan|DRUG: Lenograstim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aviation Portable Oxygen Delivery System
Status: WITHDRAWN
Conditions: Oxygen Delivery Systems at Altitude
Interventions: DEVICE: Integra Pulse Portable- Continuous flow|DEVICE: Integra Pulse Portable- Pneumatic pulsed flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
Status: TERMINATED
Conditions: Dravet Syndrome
Interventions: DRUG: Clobazam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Basic Needs to Improve Diabetes Outcomes in Medicaid Beneficiaries
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Basic needs navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lab School Day Study for CONCERTA of Older Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Placebo/ CONCERTA (methylphenidate HCl)|DRUG: CONCERTA (methylphenidate HCl) / Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beat the Blues in Pregnancy Study - Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active Transcranial Magnetic Simulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of Ultralow-dose Computed Tomography for the Detection of Pulmonary Nodules and Lung Parenchym Alterations Compared to Standard-dose CT
Status: UNKNOWN
Conditions: Multiple Pulmonary Nodules|Pulmonary Emphysema
Interventions: RADIATION: Ultralow-Dose-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Comparing the Efficacy, Tolerability and Safety Between Three Arms in Treatment of HCV in Egyptian Population
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: BIOLOGICAL: Reiferon Retard in Arm 1|DRUG: Bon one in Arm 3|DRUG: Xerovirinc in Arm 2|DRUG: Ribavirin in Arm 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Olive Leaf Tea Ingestion in Post-prandial Glycemic Response (OLIFTEA)
Status: UNKNOWN
Conditions: Blood Glucose
Interventions: OTHER: Olive leaf tea|OTHER: Placebo tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Detection Rate of Liver Metastases With Contrast Enhanced Intraoperative Ultrasound Compared to Regular Imaging
Status: COMPLETED
Conditions: Colon Cancer Liver Metastasis|Contrast Enhances Intraoperative Ultrasound|Imaging for Liver Cancer|Imaging for Liver Metastasis
Interventions: PROCEDURE: Liver Surgery|DEVICE: Contrast Enhanced Ultrasound|RADIATION: CT Scan (standard)|RADIATION: Primovist MRI (3 Tesla)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: artemether:lumefantrine (2.5 mg:30 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cyanoacrylate Glue on PICC Line Dressing Care
Status: COMPLETED
Conditions: Central Line Complication|Neonatal Disease
Interventions: DEVICE: Cyanoacrylate glue|DEVICE: Standard transparent film dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Health Partnership Program for Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Colon Cancer|Gastric Cancer|Lung Cancer
Interventions: BEHAVIORAL: Tailored health partnership program|BEHAVIORAL: Usual care and health education workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Brain Training in Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Fit Brains Training|BEHAVIORAL: Exercise + Fit Brains Training|BEHAVIORAL: Balanced And Tone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Esketamine-Propofol and Fentanyl-Propofol
Status: RECRUITING
Conditions: Hemodynamics
Interventions: DRUG: The median dose of esketamine|DRUG: The high dose of esketamine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial of An Inactivated Quadrivalent Influenza Vaccine in Healthy Subjects Aged 3 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine|BIOLOGICAL: Trivalent influenza vaccine A|BIOLOGICAL: Trivalent influenza vaccine B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of Remifentanil's ED50 for Rapid Sequence Intubation Avoiding Bradycardia and Hypotension in Adults
Status: COMPLETED
Conditions: Bradycardia|Hypotension
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Immune System Proteins in Participants With Mild to Moderate COVID-19 Illness
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Bamlanivimab|DRUG: Etesevimab|DRUG: Placebo|DRUG: VIR-7831|DRUG: Bebtelovimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Comparative Study of Calcium Hydroxide and Triple Antibiotic Paste in Intracanal Medicament in Emergency Pain Reduction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Calcium Hydroxide|DRUG: Triple Antibiotic paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Mitomycin C After Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Urothelial Carcinoma Ureter|Urothelial Cancer of Renal Pelvis
Interventions: DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Success and Survival of Dental Composite Restorations Being Repaired Instead of Being Replaced
Status: WITHDRAWN
Conditions: Failing Dental Composite Restorations
Interventions: PROCEDURE: Repair|PROCEDURE: Replace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects From a Mandibular Repositioning Appliance in Patients With Obstructive Sleep Apnea and Snoring
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Snoring|Disorders of Excessive Somnolence
Interventions: DEVICE: Mandibular repositioning appliance, adjustable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Non-invasive Brain Stimulation and Hand Tracking Rehabilitation for People With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study Evaluating Bosutinib-Letrozole Combination Versus Letrozole Alone In Post Menopausal Women With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Bosutinib|DRUG: Letrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Stage III
Interventions: COMBINATION_PRODUCT: durvalumab plus platinum-based chemotherapy (cisplatin or carboplatin plus vinorelbine or pemetrexed)|COMBINATION_PRODUCT: Durvalumab plus radiotherapy|BIOLOGICAL: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shenqi Fuzheng Injection for the Treatment of Cancer-related Fatigue in Patients(BCS) With Digestive Tract .
Status: UNKNOWN
Conditions: Carcinogenic Fatigue
Interventions: DRUG: shenqifuzheng injection|DRUG: Sodium Chloride Injection 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The BEST Study: The Efficacy of Brain Entrainment Sleep Technology in Military Healthcare Beneficiaries
Status: TERMINATED
Conditions: Sleep|Sleep Disorders|Sleep Deprivation|Sleep Disturbance|Sleep Disorders, Intrinsic|Sleep Disorders, Circadian Rhythm
Interventions: DEVICE: Brain Entrainment Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adalimumab in Severe and Acute Sciatica
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: Adalimumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: Biological: mesenchymal stem cell|DRUG: ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: BIOLOGICAL: Mogamulizumab (KW-0761)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk and Resiliency Factors in the RCMP: A Prospective Investigation
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Major Depressive Disorder|Panic Disorder|Generalized Anxiety Disorder|Trauma|Traumatic Stress Disorder|Trauma and Stress Related Disorders|Vicarious Trauma
Interventions: BEHAVIORAL: Emotional Resilience Skills Training (ERST)|BEHAVIORAL: Active Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: L-DEP Regimen as a Salvage Therapy for Refractory Epstein Barr Virus-induced Hemophagocytic Lymphohistiocytosis
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Pegaspargase|DRUG: doxorubicin|DRUG: etoposide|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS-001: Phase 1 Study of the HS-20093 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HS-20093 (Phase Ia: Dose escalation)|DRUG: HS-20093 (Phase Ib: Dose expansion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The IMAP Study Improving Management of Mildly Abnormal Pap Smears
Status: UNKNOWN
Conditions: Cervix Neoplasms
Interventions: PROCEDURE: HPV DNA testing|PROCEDURE: Conventional management (repeat Pap smear at 6 months)|PROCEDURE: Decision aid with choice of management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: How to Get a Better Dry Weight in End-stage Renal Disease (ESRD) Population for Improving Blood Pressure Control
Status: COMPLETED
Conditions: Blood Pressure|End Stage Renal Disease|Hemodialysis
Interventions: PROCEDURE: Clinical|DEVICE: electrical bioimpedance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigating COVID-19 Vaccine Immunity in Children in the Melbourne Infant Study of BCG for Allergy and Infection Reduction
Status: COMPLETED
Conditions: COVID-19|Vaccine Reaction|Immunization; Infection
Interventions: BIOLOGICAL: Tozinameran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Chitin-Glucan on Oxidized Low-Density Lipoprotein (LDL)
Status: COMPLETED
Conditions: Cardiovascular
Interventions: DIETARY_SUPPLEMENT: Chitin-Glucan|DIETARY_SUPPLEMENT: Low Dose Chitin-Glucan|DIETARY_SUPPLEMENT: Low Dose Chitin-Glucan + Olive Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain.
Status: COMPLETED
Conditions: Arthroscopy
Interventions: DRUG: Ketamine 0.5|DRUG: Ketamine 1|DRUG: % 0.9 NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK2586184 and the Effect of Food and Gender
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GSK2586184 800mg single and repeat dose|DRUG: Placebo-to-match GSK2586184|OTHER: GSK2586184 single dose taken with food|OTHER: GSK2586184 single dose taken without food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Effects on Health Status in Patients With Severe Mental Illness
Status: RECRUITING
Conditions: Exercise|Metabolic Syndrome|Mental Disorders, Severe|Severe Mental Disorder|Mental Deterioration|Physical Inactivity|Physical Disability|Health-Related Behavior
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Tolvaptan|DRUG: Placebo of tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Gluten-Free-Lactose-Free / Aronia Melanocarpa Supplemented Diet in Patients With Hashimoto's Thyroiditis
Status: NOT_YET_RECRUITING
Conditions: Hashimoto Thyroiditis
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Add on Study for Stable Schizophrenic Patients
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT