pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: gefitinib|DRUG: paclitaxel|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain
Status: RECRUITING
Conditions: Pain, Chronic|Pain Syndrome|Psychological
Interventions: BEHAVIORAL: Promoting Resilience in Stress Management|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NeuroAid In Enhancing Recovery After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebral Infarction
Interventions: DRUG: Neuroaid|DRUG: Neuroaid matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9)
Status: NOT_YET_RECRUITING
Conditions: Sleep Syncope
Interventions: DRUG: ondansetron 8 mg|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Administration of Combined Docosahexaenoic Acid and Vitamin E Supplements on Spermatogram and Seminal Plasma Oxidative Stress in Infertile Men With Asthenozoospermia
Status: COMPLETED
Conditions: Asthenozoospermia
Interventions: DIETARY_SUPPLEMENT: vitamin E|DIETARY_SUPPLEMENT: DHA|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Trans-catheter Foam Sclerotherapy of Pelvic and Atypical Lower Limb Varicosities
Status: UNKNOWN
Conditions: Venous Insufficiency
Interventions: PROCEDURE: embolotherapy of incompetent gonadal and iliac veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 99mTc-Sestamibi SPECT/CT Imaging for the Preoperative Diagnosis of Renal Oncocytoma
Status: COMPLETED
Conditions: Clinical T1 Renal Mass
Interventions: OTHER: Preoperative 99mTc-Sestamibi SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vascular Endothelial Growth Factor (VEGF) Levels in Retinal Vein Occlusion (RVO) During Anti-VEGF Treatment
Status: TERMINATED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Aflibercept Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Upper Limb tDCS in Chronic Stroke Patients (NOURISH)
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: transcranial current stimulation|BEHAVIORAL: GRASP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infections Caused by ESbL-Producing Enterobacteriaceae in Italy
Status: UNKNOWN
Conditions: Enterobacteriaceae Infections|Bacteremia|Pneumonia|Skin Diseases|Urinary Tract Infections
Interventions: BEHAVIORAL: Risk factors for infections due to ESBL+ Enterobacteriaceae|BEHAVIORAL: Risk factors for inadequate initial antimicrobial therapy|BEHAVIORAL: Overall and 30-day mortality in bad first antibiotic therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily Online Adaptation Versus Localization for MRI-Guided SBRT for Unresectable Primary or Oligometastatic Abdominal Malignancies
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreas Cancer|Cancer of the Pancreas|Hepatocellular Carcinoma
Interventions: DEVICE: Online, adaptive MR-guided SBRT|DEVICE: Online, non-adaptive MR-guided SBRT|OTHER: European Organization for Research and Treatment of Cancer (EORTC) QLQ-30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BARDA Securing Anthrax Immunity For the Elderly
Status: COMPLETED
Conditions: Anthrax
Interventions: BIOLOGICAL: BioThrax|BIOLOGICAL: AV7909|DRUG: Sodium chloride injection USP, 0.9% (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate)|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Examination of the Effect on Various Factors of Bed Baths Applied by Two Different Methods in Intensive Care Patients
Status: UNKNOWN
Conditions: Patient Care
Interventions: OTHER: Dry Wiping Bath with Single-Use Wipes|OTHER: Traditional Body Wiping Bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: VEGFR1-1084, VEGFR2-169, and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of TS-121 as an Adjunctive Treatment for Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: TS-121 10 mg|DRUG: TS-121 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tele-Rehabilitation to Improve Mild Traumatic Brain Injury Recovery and Reduce Subsequent Injury Risk
Status: RECRUITING
Conditions: Brain Concussion
Interventions: BEHAVIORAL: Virtual Neuromuscular/Dual-Task Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of HIV-1 Vaccines Based on Chimpanzee Serotypes of Ad Expressing Clade C gp140 and a CH505TF gp120 Protein Boost in Healthy, HIV- Uninfected Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: AdC6-HIVgp140|BIOLOGICAL: AdC7-HIVgp140|BIOLOGICAL: CH505TF gp120|BIOLOGICAL: GLA-SE (glucopyranosyl lipid A - stable emulsion; [labeled as AP 10-201])|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-Term Innohep® Treatment Versus a Vitamin K Antagonist (Warfarin) for the Treatment of Venous Thromboembolism (VTE) in Cancer
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Warfarin|DRUG: Innohep®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Sham Acupuncture|OTHER: No Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
Status: RECRUITING
Conditions: Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7|Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Docetaxel|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL
Status: TERMINATED
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Anti-TGF-beta Monoclonal Antibody SAR-439459|BIOLOGICAL: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Adenoma|Colorectal Adenoma With Severe Dysplasia|Colorectal Tubulovillous Adenoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: MUC1 Peptide-Poly-ICLC Vaccine|OTHER: Quality-of-Life Assessment|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Dermatological Evaluation: Acceptability With Gynecological Follow up - Dermacyd Tina Gel Sweet Flower
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Lactic acid (Dermacid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Effect of NT-I7, a Long Acting Interleukin-7, to Increase Lymphocyte Counts and Enhance Immune Clearance of SARS-CoV-2 (COVID-19)
Status: WITHDRAWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: NT-I7|DRUG: Placebo|PROCEDURE: Blood for research purposes|PROCEDURE: Blood for pharmacokinetic samples|PROCEDURE: Nasopharyngeal, oropharyngeal, or saliva swab|PROCEDURE: Blood for anti-drug antibody (ADA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Evaluation of School-based Health Promotion Programmes in Bihar, India
Status: COMPLETED
Conditions: Health Promotion
Interventions: BEHAVIORAL: SEHER Intervention delivered by TSM|BEHAVIORAL: SEHER Intervention delivered by SM|BEHAVIORAL: Tarang AEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Transobturator Sling Compared With Single-incision Mini-sling for the Treatment of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Injury Due to Sling-shot
Interventions: DEVICE: Ophira|DEVICE: Transobturator sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hepatectomy on the Prognosis of Patients With Nasopharyngeal Carcinoma Liver Metastases
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Liver Metastases
Interventions: PROCEDURE: Hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Equivalence of Intramuscular (IM) Versus Subcutaneous (SC) Applications of Long Acting Pamorelin 11.25 mg
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin Pamoate (Pamorelin® LA 11.25 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Alcohol Dependence With Gabapentin
Status: TERMINATED
Conditions: Alcohol Dependence
Interventions: DRUG: Gabapentin 2g/day divided in two doses for 24 weeks|DRUG: Placebo 2g/day divided in two doses for 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Angelica Gigas Nakai and Allium Cepa L.Extract Mixtures on the Improvement of Blood Flow
Status: UNKNOWN
Conditions: Blood Flow
Interventions: DIETARY_SUPPLEMENT: Angelica Gigas Nakai and Allium Cepa L.Extract Mixtures|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of RO7303359 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: RO7303359
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RSLV-132 in Females With Primary Sjögren's Syndrome
Status: NOT_YET_RECRUITING
Conditions: Primary Sjögren Syndrome
Interventions: DRUG: RSLV-132|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Disease
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: ezetimibe, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Scientifically Informed Written Exposure Procedure (The SCRIPTS Study)
Status: UNKNOWN
Conditions: Excessive Worry
Interventions: BEHAVIORAL: Standard Written Exposure|BEHAVIORAL: Enhanced Written Exposure|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radioactive Holmium Microspheres for the Treatment of Unresectable Liver Metastases
Status: COMPLETED
Conditions: Liver Neoplasms
Interventions: DEVICE: Holmium-166 polylactic microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Elastography in Imaging Patients With Thyroid Nodules
Status: COMPLETED
Conditions: Malignant Thyroid Gland Neoplasm|Thyroid Gland Nodule
Interventions: DEVICE: Siemens Acuson S3000 ultrasound system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AZD9291 Versus Gefitinib or Erlotinib in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic EGFR Sensitising Mutation Positive Non Small Cell Lung Cancer
Interventions: DRUG: AZD9291 80 mg/40 mg + placebo|DRUG: Placebo Erlotinib 150/100mg|DRUG: Placebo Gefitinib 250 mg|DRUG: Erlotinib 150/100 mg|DRUG: Gefitinib 250 mg|DRUG: Placebo AZD9291 80 mg/ 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: amifostine trihydrate|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC (Hepatic Artery Infusion Chemotherapy，HAIC）Plus Sintilimab and Donafenib in the First-line Treatment of Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Donafenib； Sintilimab； HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC647055|DRUG: Placebo|DRUG: TMC647055|DRUG: TMC647055|DRUG: Placebo|DRUG: TMC435|DRUG: Placebo|DRUG: TMC647055|DRUG: Placebo|DRUG: TMC647055
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis With Routine Ureteral Stent Removal
Status: RECRUITING
Conditions: Urolithiasis|UTI
Interventions: DRUG: Ciprofloxacin|DRUG: trimethoprim/sulfamethoxazole|DRUG: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: U/S Guided Transversus Thoracic and Pectoral Nerve Block Versus Pectoral Nerve Block in MRM
Status: COMPLETED
Conditions: Breast Cancer|Analgesia
Interventions: PROCEDURE: Transeversus Thoracic Plane Block (TTPB) and Pectoral Nerves (PECS) Block|PROCEDURE: Pectoral Nerves (PECS) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fertilix Supplements and Assisted Reproductive Technology
Status: WITHDRAWN
Conditions: Spermatozoa
Interventions: DIETARY_SUPPLEMENT: Fertilix|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Thoracic Surgery
Interventions: DRUG: Colchicine 0.6 mg|DRUG: Placebo Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: mesenchymal cell transplantation|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone in Alveolar Cleft Osteoplasty
Status: COMPLETED
Conditions: Cleft of Alveolar Ridge
Interventions: BIOLOGICAL: anterior iliac crest graft|BIOLOGICAL: lateral ramus cortical bone+BFPSC+NBBM|BIOLOGICAL: anterior iliac crest graft+BFPSC+NBBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia
Status: COMPLETED
Conditions: Neck Pain|Functional Dyspepsia
Interventions: OTHER: Visceral manipulation|OTHER: Control group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Orifice Translumenal Endoscopic Surgery: Laparoscopic-Assisted Transvaginal Cholecystectomy
Status: TERMINATED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Laparoscopic-assisted transvaginal cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
Status: UNKNOWN
Conditions: Hearing Loss, Sensorineural|Bilateral Vestibulopathy|Alzheimer Disease|Mild Cognitive Impairment
Interventions: OTHER: Longitudinal follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Lullaby Listened to Preterm Babies in Neonatal Intensive Care Units on Physiological Parameters and Pain
Status: UNKNOWN
Conditions: Neonatal Intensive Care|Music Therapy|Pain Responses
Interventions: OTHER: Listening to a recorded lullaby.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety and Tolerability of Adavosertib for Patients With Advanced Solid Tumours
Status: TERMINATED
Conditions: Advanced Solid Tumours
Interventions: DRUG: Adavosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Myeloma|Myelodysplastic Syndrome
Interventions: OTHER: CD4 DLI|OTHER: No DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: 5-hydroxytryptophan and Creatine|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Psychoeducational Intervention in New Mothers
Status: NOT_YET_RECRUITING
Conditions: Depression, Postpartum|Anxiety
Interventions: BEHAVIORAL: WWWT psychoeducative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of a Three-Dose Regimen of an Adenoviral HIV Vaccine (MRKAd5 HIV-1 Gag/Pol/Nef) in HIV Uninfected South African Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MRKAd5 HIV-1 gag/pol/nef|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fexofenadine in Patients With Active Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fexofenadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Conservative Management Vs. Balloon Kyphoplasty in the Treatment of VCFs in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DEVICE: Arm 2 Balloon Kyphoplasty|PROCEDURE: Conservative Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: fPAM for the in Vivo Depth Measurement of Pigmented Lesions and Melanoma Depth
Status: COMPLETED
Conditions: Pigmented Skin Lesion|Melanoma
Interventions: DEVICE: Functional photoacoustic microscopy|PROCEDURE: Standard of care surgical excision|DEVICE: Single cell photoacoustic microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Supported Employment and Skills Training in Conjunction With Pharmacotherapy in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Individual Placement and Support (Supported Employment)|BEHAVIORAL: Social Skills Training|DRUG: Olanzapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: End-range Mobilization on Time Curve of Pressure Pain Threshold
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: End-range mobilization|BIOLOGICAL: Non end-range mobilization|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1
Status: TERMINATED
Conditions: Sarcoma|Melanoma|Non-small Cell Lung Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: CMB305|BIOLOGICAL: G100|DRUG: Metronomic CPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PH 2 ADI-PEG 20 Study in Non-Hodgkin's Lymphoma Subjects Who Have Failed Prior Systemic Therapy
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Protective Ventilation During Pulmonary Lobectomy in Children
Status: COMPLETED
Conditions: Pulmonary Complication
Interventions: PROCEDURE: lung protective ventilation|PROCEDURE: Conventional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants
Status: RECRUITING
Conditions: Apnea of Prematurity|Prematurity|Infant, Premature, Diseases
Interventions: OTHER: Aroma|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab(MEDI4736) and AZD6738 Combination Therapy in Relapsed Small Cell Lung Cancer Subjects
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells; Donor and Role in Management and Reconstruction of Nonunion Fracture
Status: UNKNOWN
Conditions: Healing of Fracture
Interventions: DRUG: stem cells + hydroxy apatite|OTHER: autograft taken from iliac crest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a Self-administered QUestionnaire to Identify Levers of Adhesion Behavior to Patient's Medication in Order to Adapt the Educational Monitoring.
Status: COMPLETED
Conditions: Patient Education as Topic|Surveys and Questionnaires|Medication Adherence|Pulmonary Disease, Chronic Obstructive|Diabetes Mellitus, Type 2|Heart Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-Treatment Follow-up Study for Liver Disease Subjects With or Without Cirrhosis After Receiving Emricasan or Placebo
Status: TERMINATED
Conditions: Liver Diseases|Liver Fibrosis|Liver Cirrhosis|NASH Fibrosis|Decompensated Non-Alcoholic Steatohepatitis Cirrhosis|Orthotopic Liver Transplantation
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Impact of SBI on C. Difficile in Hospitalized UC Patients
Status: TERMINATED
Conditions: Clostridium Difficile
Interventions: OTHER: Serum-derived bovine immunoglobulin/protein isolate (SBI)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Diagnostic Performance of the S100B Protein in the Prognosis of Patients With Mild Head Trauma With Risk of Complications in Patients Over 65 Years Old.
Status: NOT_YET_RECRUITING
Conditions: Mild Head Trauma With Risk of Complications
Interventions: DIAGNOSTIC_TEST: Diagnostic performance of the S100B protein dosage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Elderly Adults
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901 (High-Dose)|BIOLOGICAL: MVC-COV1901(Mid-Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Risk Stratification Using MEESSI-AHF Scale in ED and Impact on AHF Outcomes
Status: RECRUITING
Conditions: Acute Heart Failure|Emergencies
Interventions: PROCEDURE: Risk stratification before decision-making about patient hospitalization or discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab, Bendamustine Hydrochloride, and Lenalidomide in Treating Patients With Refractory or Relapsed Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Refractory/Relapsed Indolent Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bendamustine|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Trial of Two Different Prostate Biopsy Schemes
Status: COMPLETED
Conditions: Prostate Cancer|Local Anesthesia|Prostate-Specific Antigen/Blood|Biopsy/Methods|Image-guided Biopsy/Methods|Prostatic Neoplasms/Diagnosis|Prostate/Pathology|Prospective Studies|Humans|Male|Ultrasonography, Interventional/Methods
Interventions: OTHER: 20 core-biopsy fragments|PROCEDURE: Base and apex local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Wound Infiltration Versus Caudal Block on Wound Infection and Healing in Paediatrics Inguinal Herniotomy
Status: COMPLETED
Conditions: Healing Surgical Wounds
Interventions: PROCEDURE: Caudal block|PROCEDURE: Wound infiltration|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urokinase-Plasminogen Activator (uPA) Inhibitor WX-UK1 in Combination With Capecitabine in Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: DRUG: WX-UK1 in combination with Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate (SUO11248) In Subjects W/ Metastatic And/Or Surgically Unresectable Hepatocellular Cancers (HCC)
Status: TERMINATED
Conditions: Liver Cancer
Interventions: DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Dialysate Sodium Effect on Blood Pressure Variability in Hemodialysis Patients
Status: UNKNOWN
Conditions: Hemodialysis Patients
Interventions: PROCEDURE: standard hemodialysis|PROCEDURE: lower dialysate sodium dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Bicuspid Aortic Valve
Interventions: DIETARY_SUPPLEMENT: Vitamin K2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transversus Thoracis Muscle Plane Block in Patients Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: OTHER: ultrasound-guided Transversus Thoracis Muscle Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: DRUG: MIN-102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Anesthesia Methods in IVF Procedure
Status: COMPLETED
Conditions: Oocyte Retrieval
Interventions: DRUG: propofol bolus|DRUG: propofol infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Controlled Trial of 3,4-Diaminopyridine (3-4DAP) in Lambert-Eaton Myasthenic Syndrome (LEMS)
Status: TERMINATED
Conditions: Muscle Weakness
Interventions: DRUG: 3-4 Diaminopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Exclusive Enteral Nutrition Combined With Azathioprine for Remission of Crohn's Diseases After Surgery
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: postoperative 3-month exclusive enteral nutrition|DRUG: azathioprine|OTHER: normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of Intravitreal Conbercept Injection as a Primary Treatment for Exudative Circumscribed Choroidal Haemangioma
Status: UNKNOWN
Conditions: Circumscribed Choroidal Haemangioma
Interventions: DRUG: conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea|Insomnia|Sleep Deprivation|Sleep Disorders, Circadian Rhythm|Sleepiness, Excessive Daytime|Fatigue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monotherapy Versus Placebo Over 10 Days in Integrase Naive HIV-1 Infected Adults
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV-1 Infection
Interventions: DRUG: GSK364735
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Single-port Thoracoscopic Sympathicotomy in Complex Regional Pain Syndrome Type I (CRPS)
Status: WITHDRAWN
Conditions: Complex Regional Pain Syndrome Type I of the Upper Limb
Interventions: PROCEDURE: unilateral single-port VATS sympathicotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease
Status: RECRUITING
Conditions: Critical Limb Ischemia (CLI)
Interventions: DEVICE: Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System (IBS Titan™)|DEVICE: Percutaneous Transluminal Angioplasty (PTA) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of CGM097 in Adult Patients With Selected Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor With p53 Wild Type Status
Interventions: DRUG: CGM097
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Ticagrelor 90 MG|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration.
Status: UNKNOWN
Conditions: AMD|Soft Drusen|Reticular Pseudodrusen|Drusen Stage Macular Degeneration|Drusen (Degenerative) of Macula, Bilateral
Interventions: DIETARY_SUPPLEMENT: Postbotics and Vitamins|DIETARY_SUPPLEMENT: Vitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety of ahSC in Chronic SCI With Rehabilitation
Status: COMPLETED
Conditions: Spinal Cord Injury|Paraplegia|Quadriplegia|Tetraplegia
Interventions: BIOLOGICAL: Autologous human Schwann cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma, IDH-wildtype|Glioblastoma Multiforme|Glioblastoma Multiforme, Adult|Glioblastoma Multiforme of Brain
Interventions: PROCEDURE: Tumor resection|PROCEDURE: Tumor biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma
Status: COMPLETED
Conditions: Central Nervous System Lymphoma|Intraocular Lymphoma
Interventions: DRUG: Intraventricular Rituximab Plus MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microdrilling Surgery for Full Thickness Chondral Lesions of the Knee Augmented With Concentrated Bone Marrow Aspirate, Platelet Rich Plasma and Hyaluronic Acid
Status: COMPLETED
Conditions: Unilateral Primary Osteoarthritis of Knee|Osteoarthritis Knee|Degeneration; Articular Cartilage, Knee|Degenerative Lesion of Articular Cartilage of Knee
Interventions: PROCEDURE: Microdrilling Surgery|PROCEDURE: Injections of BMAC + PRP + HA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neurofeedback on Neural Function, Neuromodulation, and Chemotherapy-Induced Neuropathic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Peripheral Neuropathy
Interventions: BEHAVIORAL: EEG biofeedback (BF) Group|BEHAVIORAL: Wait-List Control (WLC) Group|BEHAVIORAL: Follow UP Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone
Status: UNKNOWN
Conditions: Preterm Birth|Obstetric Labor, Premature
Interventions: DRUG: 17 α hydroxyprogesterone caproate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of an Immune-boosting Food Supplement on the Severity and Frequency of Pediatric Respiratory Tract Infections
Status: COMPLETED
Conditions: Immunomodulation|Respiratory Tract; Infection, Upper (Acute)
Interventions: DIETARY_SUPPLEMENT: Verum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib With Capecitabine In Breast Cancer
Status: COMPLETED
Conditions: Advanced/Metastatic Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women
Status: COMPLETED
Conditions: Fractures, Bone|Bone Marrow Disease|Fat Disorder|Adiposity
Interventions: DEVICE: Dixon Magnetic Resonance Imaging|DEVICE: dual-energy X-ray absorptiometry (DXA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Antibiotic Eye Drops on the Nasal Microbiome in Healthy Subjects
Status: RECRUITING
Conditions: Nasal and Pharyngeal Microbiome
Interventions: DRUG: Gentamicin Ophthalmic|DRUG: Ciprofloxacin Ophthalmic|DRUG: Povidone Ophthalmic|DRUG: Povidone and Benzalkonium Chloride Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Evaluation of Nasacort AQ in Children Ages 2-5 Years With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 2-Year Therapy With Teriparatide vs 1-yr Therapy Followed by 1-Year of Raloxifene or Calcium/Vit D in Severe Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Teriparatide|DRUG: Raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Eltrombopag as a Rescue of Isolated Chemotherapy-induced Thrombocytopenia
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose ITI Strategy for Children in Hemophilia A With High-titer Inhibitor and Poor ITI Risk in China
Status: UNKNOWN
Conditions: Hemophilia A With Inhibitor
Interventions: DRUG: Coagulation Factor VIII|DRUG: Prednisone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Capso Vision SV-1 to PillCam SB2 in the Evaluation of Subjects With Suspected Small Bowel Disease
Status: COMPLETED
Conditions: Intestinal Disease|Inflammatory Bowel Disease|Crohn Disease|Ulcer|Celiac Disease
Interventions: DEVICE: PillCam SB2 capsule|DEVICE: CapsoCam SV-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan Criteria
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Storytelling Video Intervention for Depressed Primary Care Patients - Pilot Trial
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: aTAU + sTVi|BEHAVIORAL: aTAU + Attention Control Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Management Strategies for the Use of Esomeprazole (Nexium) in Helicobacter Pylori Infected Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects
Status: UNKNOWN
Conditions: Diabetes Mellitis Type 2
Interventions: DRUG: DA-1229|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Coughing Frequency of Remimazolam Total Intravenous Anesthesia Versus Inhalational Anesthesia
Status: COMPLETED
Conditions: Thyroid Neoplasm|Cough
Interventions: DRUG: Total intravenous anesthesia with Byfavo|DRUG: Inhalation anesthesia with Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq)
Status: COMPLETED
Conditions: Diarrhea|Gastroenteritis
Interventions: BIOLOGICAL: RV5 (Pentavalent Rotavirus Vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Of Fat Micrografts With Adipose-Derived Stromal Vascular Fraction In Hands Of Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: ADSVF application in the right hand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT