pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Learn About How Food and Esomeprazole Affect the Level of BAY2927088 in the Blood When Taken Together in Healthy Participants
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|EGFR Mutation|HER2 Mutation|Healthy Volunteers
Interventions: DRUG: BAY2927088|DRUG: Esomeprazole|OTHER: Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Palbociclib Combined With an Aromatase Inhibitor in Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib + Letrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Fenretinide in Adult Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Fenretinide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occipital Nerve RF Between Occipital Nerve Block And Occipital Nerve Radiofrequency Ablation
Status: NOT_YET_RECRUITING
Conditions: Occipital Neuralgia|Headache
Interventions: DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Artery Hypertension
Interventions: DRUG: Metformin|DRUG: Placebo|DEVICE: mHealth Intervention|DEVICE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
Status: COMPLETED
Conditions: Preterm Birth|Prematurity|Infant,Premature|Infant Development|Child Development|Parent-Child Relations|Mental Health Wellness 1
Interventions: BEHAVIORAL: Family Integrated Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS)
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Adrenal Insufficiency
Interventions: DRUG: hydrocortisone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medical Nutrition Therapy for Medically Complex Infants in the Pediatric Outpatient Setting
Status: UNKNOWN
Conditions: Growth Failure in Medically Complex Infants|Growth Failure|Malnutrition in Medically Complex Infants|Malnutrition|Nutrition in Medically Complex Infants|Nutrition|Nutrition Disorder, Infant
Interventions: BEHAVIORAL: Standardized Medical Nutrition Therapy|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Carboplatin and Vinorelbine in Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: Carboplatin and Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study of Cyclophosphamide and Rabbit Anti-Thymocyte Globulin as Salvage Therapy in Patients With Diffuse Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency Ablation
Status: TERMINATED
Conditions: Barrett's Esophagus
Interventions: DRUG: Dexlansoprazole|DRUG: Dexlansoprazole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction
Status: COMPLETED
Conditions: Hyperglycemia|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Green Tea Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Acupressure and Aromatherapy on Nausea and Vomiting Severity, Anxiety and Comfort Level
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Patients Receiving Chemotherapy
Interventions: OTHER: Intervention 1 Group|OTHER: Intervention 2 Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fluoride Availability in Saliva After Use of Sodium Fluoride or Monofluorophosphate Toothpastes
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran (RO7198457) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Participants With Previously Untreated Advanced Melanoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma
Interventions: BIOLOGICAL: Autogene cevumeran|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological|Uterine Cervical Neoplasms|Ovarian Neoplasms|Uterine Neoplasms|Genital Neoplasms, Female
Interventions: BEHAVIORAL: GyneGals Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Coherent Breathing Breathwork on Health
Status: COMPLETED
Conditions: Stress|Anxiety|Depressive Symptoms|Wellbeing|Sleep Disturbance
Interventions: BEHAVIORAL: Coherent breathing|BEHAVIORAL: Placebo coherent breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Endometriosis: a Comparison of Medical and Surgical Therapy and Pathogenetic Considerations
Status: UNKNOWN
Conditions: Endometriosis of Umbilicus|Endometriosis in Scar of Skin|Endometriosis-related Pain|Endometriosis
Interventions: OTHER: Patients satisfaction after medical and surgical treatment for umbilical endometriosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Hypnosis in Virtual Reality on the Anxiety of Patients With Metastatic Prostate Cancer Over Chemotherapy
Status: UNKNOWN
Conditions: Metastatic Prostate Cancer
Interventions: DEVICE: HYPNO VR® device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Transdiagnostic Internet-based Protocol in Community Sample
Status: COMPLETED
Conditions: Emotional Disorders|Anxiety|Depression
Interventions: BEHAVIORAL: Transdiagnostic internet-based protocol|BEHAVIORAL: Transdiagnostic internet-based protocol + positive affect component|OTHER: Waiting List Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBI110 Single Agent and in Combination With Sintilimab in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma (r/r DLBCL)
Status: UNKNOWN
Conditions: DLBCL
Interventions: DRUG: IBI110 plus sintilimab|DRUG: IBI110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and PK Trial Evaluating the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Minocin IV
Status: WITHDRAWN
Conditions: Normal Healthy Volunteers
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index Monitoring of Sedation During Endoscopic Retrograde Cholangiopancreaticography
Status: COMPLETED
Conditions: Gastrointestinal Endoscopy|Sedation
Interventions: DEVICE: BIS monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An in Vitro Evaluation of Antimicrobial Photodynamic Therapy on Deciduous Carious Dentin
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Rubber dam isolation|PROCEDURE: Tooth drying|PROCEDURE: Dentin wash with chlorhexidine 2%|PROCEDURE: Antimicrobial Photodynamic Therapy 1|PROCEDURE: Antimicrobial Photodynamic Therapy 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind Cross-Over Trial Of Buprenorphine and Low-Dose Naloxone Versus Buprenorphine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: buprenorphine and low-dose naloxone|DRUG: buprenorphine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors
Status: TERMINATED
Conditions: ALL, Childhood|Leukemia, Lymphoblastic|Leukemia, Lymphoblastic, Acute|Leukemia, Lymphoblastic, Acute, L1|Leukemia, Lymphoblastic, Acute, L2|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive|Leukemia, Lymphocytic, Acute|Leukemia, Lymphocytic, Acute, L1|Leukemia, Lymphocytic, Acute, L2|Lymphoblastic Leukemia|Lymphoblastic Leukemia, Acute|Lymphoblastic Leukemia, Acute, Childhood|Lymphoblastic Leukemia, Acute, L1|Lymphoblastic Leukemia, Acute, L2|Lymphoblastic Lymphoma|Lymphocytic Leukemia, Acute|Lymphocytic Leukemia, L1|Lymphocytic Leukemia, L2|Brain Tumors|Cancer of the Brain|Cancer of Brain|Malignant Primary Brain Tumors|Brain Neoplasms, Malignant
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: PBC|Primary Biliary Cirrhosis
Interventions: DRUG: LUM001|DRUG: Placebo|DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
Status: RECRUITING
Conditions: Brain Tumor
Interventions: DEVICE: Blood Brain Barrier Disruption - Oncology|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Heartburn
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Dexlansoprazole MR|DRUG: Dexlansoprazole MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between WE 941 OD and Brotizolam (Lendormin®) in Healthy Adult Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: WE941 OD tablets|DRUG: Brotizolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NVD-003 in the Treatment of Congenital Pseudarthrosis of the Tibia
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Pseudarthrosis of Tibia
Interventions: BIOLOGICAL: NVD-003, an autologous 3D scaffold free osteogenic graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NC-6004 With 5-FU and Cetuximab for Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: NC-6004|DRUG: Cetuximab|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorder NOS|Schizoaffective Disorder|Schizophreniform
Interventions: DRUG: N-Acetyl Cysteine|OTHER: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer
Status: RECRUITING
Conditions: Advanced Adrenal Gland Pheochromocytoma|Advanced Paraganglioma|Metastatic Adrenal Gland Pheochromocytoma|Metastatic Paraganglioma|Stage III Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8|Stage IV Adrenal Gland Pheochromocytoma and Sympathetic Paraganglioma AJCC v8|Unresectable Adrenal Gland Pheochromocytoma|Unresectable Paraganglioma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography with Contrast|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|OTHER: Quality-of-Life Assessment|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Esarin Gel in Chronic Venous Insufficiency and Varicose Veins
Status: COMPLETED
Conditions: Chronic Venous Insufficiency|Varicose Vein|Superficial Vein Thrombophlebitis
Interventions: DRUG: Esarin Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer
Status: NO_LONGER_AVAILABLE
Conditions: Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic Mutation|Triple-Negative Breast Cancer
Interventions: DRUG: Veliparib|DRUG: Cisplatin|DRUG: Vinorelbine
Study Type: EXPANDED_ACCESS
Clinical trial: Comparison of Teriparatide With Alendronate for Treating Glucocorticoid-Induced Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Teriparatide|DRUG: Alendronate Sodium|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a 'Graft/Prosthesis, Biomaterial (DKM410)' in the Treatment of Both Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: DKM-410|DEVICE: Juvederm ULTRA PLUS XC 1.0ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Functional Motor Control on Pain, Flexibility, Lower Extremity Function With ITBS
Status: RECRUITING
Conditions: Iliotibial Band Syndrome|Pain|Flexibility
Interventions: OTHER: Functional motor control excercise|OTHER: convectional excercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety And Efficacy Of Dexmedetomidine Sedation In Intubated Mechanically Ventilated Infants With Respiratory Failure
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Dexmedetomidine 0.35µg/kg /h|DRUG: Dexmedetomidine 0.5µg/kg /h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Game-Based EMG-Biofeedback Therapy in Post-Stroke Dysphagia
Status: COMPLETED
Conditions: Stroke|Dysphagia|Surface Electromyography|Biofeedback|Swallowing Disorder
Interventions: DEVICE: With EMG-Biofeedback|BEHAVIORAL: Without EMG-Biofeedback|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics of Injection of Cisatracurium Base on Lean Body Mass Pattern to Maintain Deep Neuromuscular Blockade in Obese Patients
Status: COMPLETED
Conditions: Obese Patients|Laparoscopic Colorectal Surgery
Interventions: BEHAVIORAL: base on Lean Body Mass Pattern|BEHAVIORAL: base on Actual Body Weight|GENETIC: obese patients|GENETIC: normal patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood
Status: COMPLETED
Conditions: Dyslipidemias|Coronary Heart Disease|Combined (Atherogenic) Dyslipidemia|Mixed Dyslipidemia
Interventions: DRUG: ABT-335|DRUG: placebo|DRUG: atorvastatin|DRUG: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Microplasmin to Induce a Posterior Vitreous Detachment (MIVI III)
Status: COMPLETED
Conditions: Vitrectomy
Interventions: DRUG: Ocriplasmin 25µg|DRUG: Ocriplasmin 75µg|DRUG: Ocriplasmin 125µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Test a Marketed Product in the Treatment of Migraine-associated Nausea
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Comparator: Rizatriptan|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Alemtuzumab as a Treatment in Stabilizing Neurocognitive Function In Relapsing Remitting Multiple Sclerosis Patients
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Of 80 Mg Atorvastatin Calcium Tablets Versus 80 Mg Lipitor® Tablets Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One
Status: UNKNOWN
Conditions: Bone Resorption
Interventions: DEVICE: electric intraoral weilding|DEVICE: casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Markers for Post-Traumatic Stress Disorder
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DIAGNOSTIC_TEST: CAPS questionnaire|DIAGNOSTIC_TEST: Beck Depression Inventory|DIAGNOSTIC_TEST: The Fibromyalgia Impact Questionnaire|DIAGNOSTIC_TEST: The Pittsburgh Sleep Quality Index|DIAGNOSTIC_TEST: Depression, Anxiety and Stress Scale-21 items|DIAGNOSTIC_TEST: Traumatic Events Questionnaire|DIAGNOSTIC_TEST: Clinician Administered Dissociative States Scale|DIAGNOSTIC_TEST: A diary will be used for seven consecutive nights|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Functional brain imaging|DIAGNOSTIC_TEST: EEG analysis|DIAGNOSTIC_TEST: Autonomic nervous system monitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of Pembrolizumab in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: pembrolizumab, gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ayurvedic Treatment Package in Plaque Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Individualized internal ayurvedic treatment|OTHER: External ayurvedic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib for Relapsed and Refractory Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Relapsed and Refractory|Diffuse Large B Cell Lymphoma
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Intimate Partner Violence, Mental Health, and HIV in Antenatal Care
Status: UNKNOWN
Conditions: Partner Abuse|Depression|Adherence, Medication
Interventions: BEHAVIORAL: Asiphephe health worker training|BEHAVIORAL: Asiphephe therapeutic sessions|OTHER: IPV assessment|OTHER: Referral for IPV or Mental Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Online Tai Chi Intervention to Promote Smoking Cessation Among Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|PROCEDURE: Carbon Monoxide Measurement|OTHER: Internet-Based Intervention|DRUG: Nicotine Replacement|OTHER: Survey Administration|OTHER: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Survey to Eval Relation between Shopping and Misuse, Abuse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementing HPV DNA Self-Collection to Increase Rates of Cervical Cancer Screening in Transgender Men
Status: UNKNOWN
Conditions: Transgenderism|Cervical Cancer|Human Papilloma Virus
Interventions: DIAGNOSTIC_TEST: HPV testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Belimumab for Prevention of Chronic Graft-versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Graft Vs Host Disease|Graft-versus-host-disease
Interventions: DRUG: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hedonic and Homeostatic Appetite Control in Obesity and Type 2 Diabetes in the Context of Meal and Exercise Timing
Status: RECRUITING
Conditions: Overweight and Obesity|Type 2 Diabetes
Interventions: OTHER: Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Image Guided VATS vs. VATS Resection
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Image guided Video-Assisted Thoracic Surgery (VATS) resection|PROCEDURE: Video-Assisted Thoracic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Cortex Plasticity and the Effect of Deep Intramuscular Needling Stimulation Therapy (DIMST) in Osteoarthritis Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis|Chronic Pain
Interventions: PROCEDURE: DIMST|PROCEDURE: Placebo-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health-E You: Reducing Unintended Pregnancies Among Hispanic Adolescents
Status: COMPLETED
Conditions: Unprotected Sex|Unsafe Sex
Interventions: BEHAVIORAL: Health-E You: a computer-based intervention to improve the use of effective contraception among Hispanic adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phthalates Exposure in Type 2 Diabetic Patients and Diuretic Therapy
Status: UNKNOWN
Conditions: Renal Function Disorder|Glucose Metabolism Disorders
Interventions: DRUG: Dapagliflozin 10 MG|DRUG: Hydrochlorothiazide 12.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ZAGAL Study: Evaluating Effectiveness and Tolerability of Zonisamide as Adjunctive Therapy in Patients With Partial Onset Seizures Treated With Two Antiepileptic Drugs
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Purastat® vs Standard Therapy for Haemostasis During Endoscopic Submucosal Dissection
Status: COMPLETED
Conditions: Gastrointestinal Haemorrhage
Interventions: DEVICE: PuraStat®|PROCEDURE: Electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Moderate Carbohydrate Diet in Children With Type 1 Diabetes on Hybrid Closed-loop Therapy
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Moderate carbohydrate diet|OTHER: Traditional diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esthetic and Clinical Assessment of Injectable Resin Composite Technique
Status: NOT_YET_RECRUITING
Conditions: Clinical Performance
Interventions: PROCEDURE: Injectable resin composite technique.|PROCEDURE: Conventional layering technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial of the CALM Intervention
Status: RECRUITING
Conditions: Anxiety Disorder of Childhood
Interventions: BEHAVIORAL: Child Anxiety Learning Modules (CALM)|BEHAVIORAL: Child Anxiety Learning Modules--Relaxation (CALM-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Radiation Therapy for Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Grade Glioma|WHO Grade 3 Glioma With IDH1 Mutation|WHO Grade 3 Glioma With 1p/19q Codeletion
Interventions: RADIATION: Proton radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ellume·Lab Flu A+B Test and the Ellume Home Flu Test Performance Versus Viral Culture and Reverse Transcriptase Polymerase Chain Reaction
Status: COMPLETED
Conditions: Influenza
Interventions: DIAGNOSTIC_TEST: Ellume Home Flu Test|DIAGNOSTIC_TEST: ellume.lab Flu A+B Test|DIAGNOSTIC_TEST: Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)|DIAGNOSTIC_TEST: Viral culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Hippotherapy on Functionality in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Equine-assisted therapy|OTHER: Traditional Pediatric Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High Intensity Laser for Provoked Vestibulodynia
Status: RECRUITING
Conditions: Vulvodynia
Interventions: RADIATION: High Intensity Laser Therapy (HILT)|RADIATION: Sham High Intensity Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study
Status: COMPLETED
Conditions: Intracranial Aneurysm|Subarachnoid Hemorrhage
Interventions: DEVICE: Hydrogel coil|DEVICE: Bare platinum coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Enhancement of Bone Bonding of Hip Prosthesis in Postmenopausal Women
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DRUG: Denosumb|DRUG: Placebo (for denosumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking WHO Step III Analgesics But Showing a Lack of Tolerability
Status: TERMINATED
Conditions: Pain|Chronic Pain|Low Back Pain|Neuropathic Pain|Nociceptive Pain
Interventions: DRUG: Tapentadol Prolonged Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Stiffness Measurement Predicts VOD/SOS Development (ELASTOVOD ITALIAN MULTICENTRIC STUDY)
Status: COMPLETED
Conditions: Veno Occlusive Disease, Hepatic|Sinusoidal Obstruction Syndrome|Stem Cell Transplant Complications
Interventions: DEVICE: LSM assessed by Elastographic Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: MEDI0618|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of FID 114657 in Dry Eye Subjects
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: OTHER: FID 114657 (ORB Preserved Ocular Emulsion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Fluoropyrimidine-based Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Intervention to Support Healthy Eating and Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Economics intervention (BE mHealth)|BEHAVIORAL: Standard mHealth intervention (mHealth)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics and Safety Study of BIIB132 in Adults With Spinocerebellar Ataxia 3
Status: TERMINATED
Conditions: Spinocerebellar Ataxia Type 3
Interventions: DRUG: BIIB132|DRUG: BIIB132-Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery
Status: RECRUITING
Conditions: Spinal Fusion
Interventions: DRUG: Abaloparatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staying Positive With Arthritis Study
Status: COMPLETED
Conditions: Arthritis
Interventions: BEHAVIORAL: Positive Activities (PA) Program|BEHAVIORAL: Attention Control (AC) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open-label Continuation Trial to Assess the Continued Efficacy and Safety of Ascending Doses of Lacosamide in Subjects With Chronic Refractory Neuropathic Pain
Status: COMPLETED
Conditions: Chronic Refractory Neuropathic Pain
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: LY3871801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Cupping Therapy in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Pain, Chronic|Pain
Interventions: OTHER: Dry cupping therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between Antimalarial and Anti-HIV Medications
Status: COMPLETED
Conditions: HIV Infections|Malaria
Interventions: DRUG: Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of 3% Hypertonic Saline Inhalation (24h vs 72h) to Treat Acute Bronchiolitis in Hospitalized Infants
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: 3 % hypertonic saline up to 72H|DRUG: 3 % hypertonic saline up to 24H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation|Catheter Ablation|Pulmonary Vein Isolation|Posterior Wall Isolation
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Left posterior wall isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Web-Based Body Image Intervention for Coaches of Adolescent Girls - Pilot
Status: COMPLETED
Conditions: Intervention|Waitlist Control
Interventions: BEHAVIORAL: Body Confident Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antimicrobial Photodynamic Therapy Mediated by Papain Gel on Peri-Implantitis Lesions
Status: UNKNOWN
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Conventional treatment|RADIATION: aPDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)
Status: COMPLETED
Conditions: Soft Tissue Sarcoma|Bone Tumor
Interventions: DRUG: trabectedin|DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Intake in Patients With Colorectal or Lung Cancer When Receiving a Nutritional Supplement
Status: COMPLETED
Conditions: Colorectal Cancer|Lung Cancer
Interventions: DIETARY_SUPPLEMENT: 125 mL Fortimel/Nutridrink Compact Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Spinal Manipulation in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: PROCEDURE: Spinal Manipulation|PROCEDURE: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure for Perimenopausal Women With Anxiety
Status: UNKNOWN
Conditions: Auricular Acupressure|Anxiety|Menopause|Insomnia
Interventions: OTHER: auricular acupressure|OTHER: sham acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Needling Versus Ultrasound Guided Corticosteroid Injection Alone, a Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Calcific Tendinitis
Interventions: OTHER: Us guided needling|OTHER: corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Obesity and Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder|Obesity
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|BEHAVIORAL: CBT and BWL|BEHAVIORAL: Behavioral Weight Loss Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: custirsen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9712: Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage III Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dapagliflozin in Asian T2DM Subjects With Inadequate Glycemic Control on Metformin/Saxagliptin
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 10 mg|DRUG: Dapagliflozin 5 mg|DRUG: Dapagliflozin 10 mg placebo to match|DRUG: Dapagliflozin 5 mg placebo to match|DRUG: Saxagliptin 5 mg|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Trastuzumab-emtansine in Patients With HER2-positive Metastatic Colorectal Cancer Progressing After Trastuzumab and Lapatinib.
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotechnology Following Traumatic Brain Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Concussion Symptoms|Insomnia|Pain, Chronic|Depressive Symptoms
Interventions: DEVICE: HIRREM-SOP or Cereset|DEVICE: Cereset 2x
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IBI389 Single Agent, and in Combination With Sintilimab, in Patients With Advanced Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: IBI 308 injection|DRUG: IBI 389 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Study to Assess Safety and Efficacy in the Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (R/R-AML)
Interventions: DRUG: QHRD107 capsule，Venclexta and Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Straumann Roxolid Multi-Center Study
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Straumann Bone Level Implants, 4.1 mm implant diameter|DEVICE: Straumann Bone Level Implants, 3.3 mm implant diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAFE-AP: Automatic Control of Blood Glucose Under Announced and Unannounced Exercise
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Closed-loop controller with exercise mitigation module|DEVICE: Closed-loop controller without exercise mitigation module|DEVICE: Open-loop insulin infusion system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers
Status: TERMINATED
Conditions: MUC17-positive Solid Tumors
Interventions: DRUG: AMG 199
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adolescent Suicide Attempters (TASA)
Status: COMPLETED
Conditions: Depression|Suicide, Attempted
Interventions: DRUG: fluoxetine|DRUG: sertraline|DRUG: citalopram|DRUG: escitalopram|DRUG: bupropion|DRUG: mirtazapine|DRUG: venlafaxine|DRUG: lithium|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Contrast-induced Nephropathy
Interventions: PROCEDURE: Primary percutaneous coronary intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth
Status: COMPLETED
Conditions: Pulpal Necrosis
Interventions: PROCEDURE: Left Tooth Platelet Rich Fibrin; Right Tooth Implant Alone|PROCEDURE: Right Tooth Platelet Rich Fibrin; Left Tooth Implant Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs
Status: COMPLETED
Conditions: Hepatitis C|Medication Adherence
Interventions: DEVICE: AiCure|DEVICE: AiCure with gamification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capnography During Percutaneous Endoscopic Gastrostomy (PEG)
Status: UNKNOWN
Conditions: In the Study the Value of Capnography for Avoiding Complications During Sedation for PEG is Evaluated.
Interventions: DEVICE: Capnography|DEVICE: Standard monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Quality of Life and the Level of Precarity of a Diabetic Population With and Without Foot Ulcer in Martinique
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus|Foot Ulcer, Diabetic|Diabetes Complications
Interventions: OTHER: Self-assessment questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Hypofractionated Proton Radiation Therapy in Thoracic Malignancies
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Small Cell Lung Cancer|Carcinoid|Thymic Cancer|Lung Cancer
Interventions: RADIATION: Proton Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT