pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer|Anatomic Stage II Breast Cancer|Anatomic Stage III Breast Cancer|Invasive Breast Lobular Carcinoma
Interventions: PROCEDURE: Endocrine Therapy|PROCEDURE: Biopsy of breast|DRUG: Neratinib|PROCEDURE: Biospecimen Collection|PROCEDURE: Mammogram|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Breast Surgery|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of PPI-668 (NS5A Inhibitor) Plus Sofosbuvir, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype-4
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: ravidasvir hydrochloride|DRUG: sofosbuvir|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex 2 mg/kg|DRUG: Sugammadex 4 mg/kg|DRUG: Neostigmine + Glycopyrrolate|DRUG: Neostigmine + Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Levels of Capsaicin After Intra-Articular Injection and Topical Application in Patients With Painful Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: CNTX-4975-05|DRUG: Qutenza|DRUG: Lidocaine (without epinephrine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Isoglycyrrhizinate Followed by Diammonium Glycyrrhizinate and Combined With Entecavir in Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis b|Liver Inflammation
Interventions: DRUG: Entecavir|DRUG: Magnesium Isoglycyrrhizinate|DRUG: Diammonium Glycyrrhizinate|DRUG: Magnesium Isoglycyrrhizinate Placebo|DRUG: Diammonium Glycyrrhizinate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia
Status: UNKNOWN
Conditions: Familial Hypercholesterolemia - Homozygous|Lipid Metabolism Disorders|Proprotein Convertase Subtilisin/Kexin 9
Interventions: BIOLOGICAL: IBI306
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin and Colonic Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin|DRUG: Placebo|OTHER: Bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Clinical Study to Evaluate Z7200 (Budesonide/Formoterol) Pharmacokinetics Profile in Healthy Volunteers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Z7200 without oral activated charcoal|DRUG: Symbicort Turbohaler without oral activated charcoal|DRUG: Z7200 with oral activated charcoal|DRUG: Symbicort Turbohaler with oral activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diaphragmatic Training on Urgency Urinary Incontinence in Postmenopausal Women
Status: COMPLETED
Conditions: Urge Incontinence|Urinary Incontinence|Postmenopausal Disorder
Interventions: DRUG: anti muscarinic drugs|OTHER: Instructions including bladder training|OTHER: pelvic floor muscle training (PFMT)|OTHER: abdominal exercise|OTHER: Diaphragmatic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis
Status: COMPLETED
Conditions: Prostatitis
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cataract Surgery With Intracameral Triamcinolone in Infants
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Triamcinolone acetonide|DRUG: Prednisolone syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Through Combined tACS Therapy in Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: COMBINATION_PRODUCT: Combined tACS and Cognitive Training Program|BEHAVIORAL: Traditional Cognitive Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The LIMO Study, Lucentis for Treatment of Uveitic Patients With Refractory Cystoid Macular Oedema
Status: COMPLETED
Conditions: Uveitis Related Cystoid Macular Edema|Steroid-induced Glaucoma - Borderline
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Evaluation of the Nipro Elisio™ Dialyzer
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DEVICE: Elisio-210H|PROCEDURE: conventional hemodialysis|PROCEDURE: on line hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Korean Red Ginseng on Fatigue in Patients With Rheumatic Disease
Status: UNKNOWN
Conditions: Sjögren's Syndrome|Rheumatic Diseases|Korean Red Ginseng
Interventions: DIETARY_SUPPLEMENT: Korean Red Ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation
Status: RECRUITING
Conditions: Behavior, Health Risk|Implementation Science|E Cigarette Use|Cessation, Smoking|Incentives|Engagement, Patient|Peer Support|Media Literacy
Interventions: BEHAVIORAL: Text-massaging suport|BEHAVIORAL: Financial incentive|BEHAVIORAL: Media literacy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Storytelling Through Music Intervention With Bereaved Parents
Status: COMPLETED
Conditions: Pediatric Cancer|Grief|Well-Being, Psychological|Coping Strategies|Bereavement
Interventions: BEHAVIORAL: Storytelling Through Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Efficacy of Intravenous Iclaprim Versus Vancomycin in the Treatment of Hospital-Acquired, Ventilator-Associated, or Health-Care-Associated Pneumonia
Status: TERMINATED
Conditions: Hospital-Acquired Pneumonia|Ventilator-Associated Pneumonia|Health-Care-Associated Pneumonia
Interventions: DRUG: iclaprim|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of PFMT and MPE in Elderly Women With SUI.
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Pelvic Floor Disorders|Aging
Interventions: OTHER: Pelvic Floor Muscle Training|OTHER: Modified Pilates Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of LX6171 in Elderly Volunteers With Age Associated Memory Impairment
Status: COMPLETED
Conditions: Age-Related Memory Disorders
Interventions: DRUG: LX6171 High Dose|DRUG: LX6171 Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caplacizumab Single and Multiple Dose Study in Healthy Japanese and White Subjects.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Caplacizumab Dose 1 iv (single-dose)|BIOLOGICAL: Caplacizumab Dose 2 iv (single-dose)|BIOLOGICAL: Caplacizumab Dose 2 sc (single-dose)|BIOLOGICAL: Caplacizumab Dose 2 sc (multiple-dose)|OTHER: Placebo iv (single-dose)|OTHER: Placebo sc (single-dose)|OTHER: Placebo sc (multiple-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor Cancers|Medulloblastoma|Basal Cell Carcinoma
Interventions: DRUG: LDE225
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: IDP-108|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FDG PET-Scan Analysis of Evolutivity of Non-surgical Aneurysm of Abdominal Aorta
Status: COMPLETED
Conditions: Medically-treated Aneurysm of Abdominal Aorta
Interventions: OTHER: PET-Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Home Exercise to Enhance Mobility for Older Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: BEHAVIORAL: home exercise/physical activity (PA) enhancement program with behavioral support|BEHAVIORAL: flex and toning health education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Healing Touch on Post Operative Pediatric Patients
Status: COMPLETED
Conditions: Surgery|Stress|Pain|Children|Post-Traumatic Stress Disorder
Interventions: PROCEDURE: Healing Touch|PROCEDURE: Healing Touch Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Pulmonary Hypertension|Pulmonary Vascular Resistance Abnormality
Interventions: DIAGNOSTIC_TEST: non-contrast chest CT|DIAGNOSTIC_TEST: spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis|DIAGNOSTIC_TEST: Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood|DIAGNOSTIC_TEST: supine bike exercise during right heart catheterisation|DIAGNOSTIC_TEST: Lung ventilation/perfusion SPECT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers
Status: RECRUITING
Conditions: Lung Carcinoma
Interventions: OTHER: Educational Intervention|OTHER: Educational Intervention|OTHER: Exercise Intervention|OTHER: Medical Device Usage and Evaluation|OTHER: Physical Performance Testing|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and PK/PD of JMT103 in Patients With Bone Metastases From Tumors
Status: UNKNOWN
Conditions: Bone Metastases
Interventions: BIOLOGICAL: Anti-RANKL Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SELINEXOR in Combination w/Bevacizumab and Atezolizumab in Newly Diagnosed Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Selinexor Pill|DRUG: Bevacizumab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Use Disorder and Cannabidiol
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
Status: RECRUITING
Conditions: ALS (Amyotrophic Lateral Sclerosis)|Postpoliomyelitis Syndrome|Spinal Muscular Atrophy
Interventions: PROCEDURE: 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis|Recurrence
Interventions: DRUG: Metronidazole Oral|DRUG: "Metronidazole" and "Lactobacillus"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A-dmDT390-bisFv(UCHT1) Immunotoxin Therapy for Patients With Cutaneous T-Cell Lymphoma (CTCL)
Status: COMPLETED
Conditions: T-cell Lymphomas|T-cell Leukemia|Sezary Syndrome|Mycosis Fungoides|Cutaneous T-cell Lymphoma (CTCL)
Interventions: BIOLOGICAL: A-dmDT390-bisFv(UCHT1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Rebound Therapy in the Rehabilitation of Children With Spastic Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: DEVICE: Rebound Therapy|OTHER: Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: gefitinib|RADIATION: radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Analytes in Blood Collected Using an Investigational Collection Device With a Commercial Predicate
Status: WITHDRAWN
Conditions: Diabetes|Anemia
Interventions: DEVICE: TAP20-C|DEVICE: SAFE-T-FILL CAPILLARY BLOOD COLLECTION SYSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ABSORB: Postmarketing Surveillance Registry to Monitor the Everolimus-eluting Bioresorbable Vascular Scaffold in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Myocardial Ischemia|Coronary Disease|Coronary Restenosis|Heart Diseases|Coronary Stenosis|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Imatinib Versus Interferon as Adjuvant Therapy in KIT-mutated Melanoma
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: imatinib|DRUG: Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Children's Nail Bed Injuries : Study of the Efficacy of the Simple Relocation of Nail Plate
Status: TERMINATED
Conditions: Nail Bed Injury
Interventions: PROCEDURE: Simple relocation of the nail plate in nailbed injuries in paediatric population
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: dacomitinib|RADIATION: Radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission
Status: COMPLETED
Conditions: Congenital Amegakaryocytic Thrombocytopenia|Diamond-blackfan Anemia|Fanconi Anemia|Leukemia|Severe Congenital Neutropenia|Thrombocytopenia
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: fludarabine phosphate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: His Bundle Pacing Versus Right Ventricular Pacing
Status: UNKNOWN
Conditions: Pacing-Induced Cardiomyopathy
Interventions: DEVICE: His bundle pacing|DEVICE: Right ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Modulation of Autonomic Cardiac Nervous System
Status: UNKNOWN
Conditions: Autonomic Nervous System|Heart Rate Variability|Muscle Sympathetic Nerve Activity
Interventions: OTHER: Modulation of muscle sympathetic nerve activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Marketing Variable on Effect of Active Drugs
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: High price|DRUG: Low price|DRUG: Low price participants aware paying part|DRUG: No price|DRUG: Free of charge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Metabolic Surgery Compared to the Best Clinical Treatment in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Complications of Diabetes Mellitus
Interventions: OTHER: Clinical Treatment|PROCEDURE: Roux-En-Y gastric bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Audio Book and Local Vibration on Pain and Fear in Intramuscular Injection in Children
Status: RECRUITING
Conditions: Procedural Pain
Interventions: BEHAVIORAL: Audio Book Group|DEVICE: Local Vibration Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective, Open-Label, Multi-center Comparison of Lymphoseek Identified Lymph Nodes and Clinically Identified Lymph Nodes of Subjects With Known Cancer of the Anus
Status: WITHDRAWN
Conditions: Anal Cancer
Interventions: DRUG: Lymphoseek
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Manganese Restriction in Neonatal Parenteral Nutrition
Status: COMPLETED
Conditions: Infant, Newborn, Disease
Interventions: OTHER: Manganese omission|OTHER: 5 mCg/kg/day manganese from "Multitrace-4 Neonatal."
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CTP-543 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CTP-543|DRUG: Placebo for CTP-543
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Dietary Lauric Acid on the Production of the LRH-1 Ligand, Dilauroylphosphatidylcholine
Status: COMPLETED
Conditions: Diet Modification
Interventions: OTHER: Lauric acid (coconut oil)|OTHER: No Lauric acid (olive oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Intermittent Negative Pressure on Wound Healing and Peripheral Circulation in Spinal Cord Injured Subjects
Status: COMPLETED
Conditions: Wound Healing, Leg and Foot Ulcers, Macrocirculation, Microcirculation
Interventions: DEVICE: Intermittent negative pressure device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Acute Coronary Syndrome
Interventions: DRUG: Alogliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Tests How Different Doses of BI 1291583 Are Taken up in the Body and How Well They Are Tolerated
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 1291583|DRUG: Matching placebo: Tartaric acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Norspan Versus Oxycontin as Postoperative Painkiller to Proximal Extracapsular Fractures of the Femur
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Buprenorphine|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: YAZ Post Authorization Safety Study (PASS)/Post Authorization Efficacy Study (PAES) in China
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EE20/DRSP (YAZ, BAY86-5300)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation for Chronic Pelvic Pain Management
Status: COMPLETED
Conditions: Chronic Pelvic Pain
Interventions: BEHAVIORAL: Mindfulness meditation|BEHAVIORAL: Relaxation app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Pharmacokinetics of Methotrexate Given With and Without AZD9056 in Rheumatoid Arthritis Patients
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD9056|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety and Preliminary Efficacy of CLL1 and CD38 Dual CAR-T in r/r AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CLL1 and CD38 dual-target CAR-T injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: ZP4207|DRUG: GlucaGen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose and Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-1816 in Healthy Subjects
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: SHR-1816|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: In It Together: Using Acceptance and Commitment Therapy to Treat Distress Among Older Adults With Sensory Loss and Their Spouses
Status: COMPLETED
Conditions: Sensory Loss (Impairment of Sight and/or Hearing)
Interventions: BEHAVIORAL: English: In It Together (IIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Treatment to Improve Symptom Management of Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia|FMS
Interventions: DEVICE: Light therapy A (Bright) via the Re-Timer®|DEVICE: Light therapy B (Dim) via the Re-Timer®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Combination of Acalabrutinib With R-CHOP for Patient Diffuse Large B-cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: R-CHOP + acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estrogen, Diabetes, and Endothelial Function
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Cetrorelix acetate, 0.25 mg/day|DRUG: Estradiol Patch, 0.025 Mg/24 Hours Weekly Transdermal Film, Extended Release|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inappropriate Polypharmacy in Elderly Patients in Primary Care and Deprescribing in Older Patients With Frailty
Status: NOT_YET_RECRUITING
Conditions: Medication Overuse|Deprescriptions|Polypharmacy|Frailty Syndrome
Interventions: OTHER: Medication Reviews and Deprescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Combination of Lenalidomide and DTIC (Dacarbazine) in Patients With Metastatic Malignant Melanoma Previously Untreated With Systemic Chemotherapy
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: CC-5013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Pseudoexfoliation Glaucoma
Interventions: DRUG: prednisolone 1%|DRUG: ketorolac 0.5%|DRUG: Artificial Tears (Methyl cellulose drops)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premature Newborn Pain Management: The Effects of Breast Milk Odor and White Noise
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Breast milk olfactory stimulation|BEHAVIORAL: White noise auditory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery
Status: COMPLETED
Conditions: Intraocular Lens Associated Postoperative Inflammation
Interventions: DRUG: Imprimis Dropless|DRUG: Imprimis Less Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plyometric Work Together With the Use of Ballast Weight in Lower Limbs in the Improvement of Performance in Jumpers
Status: COMPLETED
Conditions: Athletes
Interventions: OTHER: Plyometric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing Systemic Therapy Alone and With Local Ablative Treatment for Stage IV NSCL Cancer Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)|Stage IV
Interventions: OTHER: Systemic therapy alone or in combination with LAT (surgery and/or radiotherapy)|OTHER: Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: Saliva obtaining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese Patient
Status: COMPLETED
Conditions: Ibuprofen|Ketorolac|Colorectal Cancer
Interventions: DRUG: IV ibuprofen|DRUG: IV ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Status: RECRUITING
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Centered Health Technology Medication Adherence Program for African American Hypertensives
Status: UNKNOWN
Conditions: Hypertension|Medication Non-Adherence
Interventions: BEHAVIORAL: SMASH|BEHAVIORAL: Enhanced SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cetuximab in Combination With Paclitaxel Plus Cisplatin Versus Paclitaxel Plus Cisplatin Alone for the First-line Treatment of Metastatic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Cancer, Squamous Cell|Cetuximab Effect|Chemotherapy Effect
Interventions: DRUG: cetuximab|DRUG: cisplatin plus paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Creatine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas
Status: RECRUITING
Conditions: Soft Tissue Sarcomas
Interventions: RADIATION: Ultra-Hypo-fractionation Radiotherapy|PROCEDURE: Resection|OTHER: Questionnaire Administration|RADIATION: Moderately-Hypo-fractionation Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFS of the DUO System for Tricuspid Regurgitation (TANDEM II)
Status: RECRUITING
Conditions: Tricuspid Regurgitation|Tricuspid Valve Insufficiency|Tricuspid Valve Disease|Heart Valve Diseases
Interventions: DEVICE: DUO Transcatheter Tricuspid Coaptation Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: DEVICE: RISES-T System|OTHER: Occupational/Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effect of Distractive Auditory Stimuli (Music) on Dyspnea and Anxiety During Exercise in Adults With Chronic Respiratory Diseases
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Distractive Auditory Stimuli|PROCEDURE: No Distractive Auditory Stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Tolerability Study of Administration of PSD502
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DRUG: Intervention A|DRUG: Intervention B|DRUG: Intervention C|DRUG: Intervention D|DRUG: Intervention E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for the Treatment of Refractory Obsessive-compulsive Disorder (OCD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Fish Oil Supplements vs. Placebo for Patients With Non-alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Fatty Liver
Interventions: DRUG: Omega 3 Fish Oil supplements|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fitness After Stroke Trial
Status: RECRUITING
Conditions: Stroke|Stroke, Ischemic|Stroke Hemorrhagic
Interventions: BEHAVIORAL: Exercise MICT|BEHAVIORAL: Exercise HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Two Commonly Used Soft Tissue Grafting Techniques to Achieve Coronal Flap Advancement and Root Coverage
Status: ACTIVE_NOT_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: VISTA|PROCEDURE: STA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUCAS Chest Compressor Versus Manual Chest Compression in Out-of-hospital Sudden Cardiac Arrest. LUCAT Trial
Status: UNKNOWN
Conditions: Sudden Cardiac Arrest
Interventions: DEVICE: LUCAS (Lund University Cardiac Assist Sysrem)|OTHER: Manual chest compressions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)
Status: RECRUITING
Conditions: Pain, Chronic|Pain, Postoperative|Anesthesia|Surgery|Anxiety|Stress
Interventions: OTHER: Pain Neuroscience Education|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colorectal Inflammatory Response to a Western-Style Diet
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Western-style diet (WD)|DIETARY_SUPPLEMENT: Prudent Diet (PD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicentre, Randomised, Double-blind, Placebo-controlled Proof of Concept Study to Compare the Efficacy and Safety of r-hLIF (Emfilermin) for Improving Embryo Implantation Following in Vitro Fertilization (IVF) and Embryo Transfer (ET) in Women With Recurrent Implantation Failure
Status: COMPLETED
Conditions: Infertility Implantation Failure
Interventions: DRUG: Emfilermin, recombinant human leukemia inhibitory factor (r-hLIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Immunogenicity After MG1111(BARICELA Inj.) as 2nd Vaccination in 4 ~ 6 Year Old Healthy Children With a History of 1st Varicella Vaccination
Status: RECRUITING
Conditions: Varicella
Interventions: BIOLOGICAL: MG1111 (BARICELA)|BIOLOGICAL: VARIVAX|BIOLOGICAL: Suduvax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Active Implicit Priming|BEHAVIORAL: Control Implicit Priming|BEHAVIORAL: Food Exposure Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism
Status: UNKNOWN
Conditions: Autism|Autistic Disorder|Child Development Disorders, Pervasive|Gastrointestinal Diseases|Signs and Symptoms, Digestive
Interventions: DRUG: Oralgam (human immunoglobulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Olaparib Tablets for Subjects With Advanced Solid Tumours.
Status: COMPLETED
Conditions: Malignant Solid Tumor
Interventions: DRUG: Olaparib Treatment A|DRUG: Olaparib Treatment B|DRUG: Olaparib Treatment C|DRUG: Olaparib Treatment D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy and Safety of AryoGen Pharmed Biosimilar Denosumab 60 mg (Arylia) Versus Prolia® in Improvement of Bone Mineral Densitometry (BMD) Among Osteoporotic Postmenopausal Women
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Denosumab|DIETARY_SUPPLEMENT: calcium|DIETARY_SUPPLEMENT: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Efficacy of Different Masks With and Without a Peripheral Sealing Device, Against Covid-19
Status: COMPLETED
Conditions: Covid19|Personal Protective Equipment
Interventions: DEVICE: Peripheral sealing device for surgical mask or filtering face piece|DEVICE: IIR Surgical mask with Filtering face piece
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Scaling-up Psychological Interventions With Syrian Refugees in Switzerland
Status: COMPLETED
Conditions: Distress|PTSD|Anxiety|Depression|Trauma|Functional Disabilities|Common Mental Health Problems
Interventions: BEHAVIORAL: Problem Management Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Versus Parenteral Nutrition Support to Improve Protein Balance in Colorectal Surgical Patients
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Oral Nutrition with dextrose and pressurized whey protein|DIETARY_SUPPLEMENT: Peripheral Parenteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is There A Role For Mechanical Stimulation In Ovarian Follicular Activation?
Status: NOT_YET_RECRUITING
Conditions: Infertility, Female|Premature Ovarian Failure|IVF
Interventions: PROCEDURE: Ovarian puncture|OTHER: Hormonal blood Test|DIAGNOSTIC_TEST: Transvaginal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Arhalofenate|DRUG: Allopurinol|DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC)
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Adebrelimab+TP/FP+ radiation therapy|DRUG: Adebrelimab+FP/TP+ radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Endocrine Therapy-Induced Alopecia|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Minoxidil|DRUG: Minoxidil|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Pegylated Interferon Alfa (Peginterferon Alfa)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SPSIPB for Breast Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Opioid Consumption
Interventions: PROCEDURE: Serratus posterior superior intercostal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In Vitro Activity of Ceftolozane/Tazobactam and Imipenem/Relebactam in Clinical Isolates of Pseudomonas Aeruginosa and Enterobacterales Collected From Hematology and Oncology Patients
Status: UNKNOWN
Conditions: Ceftolozane/Tazobactam|Imipenem/Relebactam|Hematology and Oncology
Interventions: DRUG: Ceftolozane/tazobactam|DRUG: imipenem- relebactam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammoplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: SKY0402 + bupivacaine HCl|DRUG: Mid-dose SKY0402 + bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Pulmonary Fibrosis|Pulmonary Hypertension
Interventions: COMBINATION_PRODUCT: INOpulse®|COMBINATION_PRODUCT: Placebo|COMBINATION_PRODUCT: Long Term Follow Up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAP vs QLB in Patients After Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section|Postoperative Pain
Interventions: PROCEDURE: TAP (transversus abdominis plane block)|PROCEDURE: QL (quadratus lumborum block)|DRUG: Ropivacaine|DEVICE: Needle|DRUG: paracetamol|DRUG: metamizole|DRUG: Ketoprofen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of Supra-Sternal Tube-Tip Palpation
Status: UNKNOWN
Conditions: Tracheal Intubation
Interventions: PROCEDURE: Supra-Sternal Tube-Tip Palpation (SSTTP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain
Status: COMPLETED
Conditions: Left Ventricular Dysfunction|Spinal Anesthetics Causing Adverse Effects in Therapeutic Use|Global Cardiac Wall Motion Dysfunction
Interventions: DRUG: Intrathecal local anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p