pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia
Status: TERMINATED
Conditions: Polycythemia Vera|Essential Thrombocythemia
Interventions: DRUG: Momelotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWP14012 on Maintaining Healing in Subjects With Healed Erosive Esophagitis
Status: UNKNOWN
Conditions: Healed Erosive Esophagitis
Interventions: DRUG: DWP14012 20 mg|DRUG: DWP14012 20 mg placebo|DRUG: Lansoprazole 15 mg|DRUG: Lansoprazole 15 mg Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label Posterior Juxtascleral Injections of Anecortave Acetate 15mg Dose for Long Term Use in Patients With AMD
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: Anecortave Acetate (AL-3789) Sterile Suspension, 30 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Plenum® Tissue Ortho to Prevent Epidural Fibrosis and Post-laminectomy Syndrome.
Status: NOT_YET_RECRUITING
Conditions: Herniated Disk Lumbar
Interventions: DEVICE: Plenum® Tissue ortho membrane (polydioxanone membrane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of the Combination of Thiotepa and Pomalidomide for the Treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma Patients.
Status: RECRUITING
Conditions: Relapsed or Refractory (R/R) Primary Central Nervous System Lymphoma
Interventions: DRUG: thiotepa combined with pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy
Status: COMPLETED
Conditions: Relapsed or Refractory Peripheral T-Cell Lymphoma
Interventions: DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranberry Juice for the Prevention of Recurrent Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Cranberry juice cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Granulocyte Colony-stimulating Factor on Clinical Pregnancy Rate in Patients With Endometriosis
Status: UNKNOWN
Conditions: Recurrent Implantation Failure|Endometriosis
Interventions: DRUG: Granulocyte Colony-Stimulating Factor|PROCEDURE: Intrauterine infusion of normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membranes
Interventions: DRUG: vitamine C and E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Effect of Tranexamic Acid on the Incidence of Deep Venous Thrombus in Cardiac Surgery
Status: UNKNOWN
Conditions: Thromboses, Deep Vein|Tranexamic Acid Adverse Reaction
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae vs. PENG Block for Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthropathy|Hip Osteoarthritis|Hip Pain Chronic
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block|DRUG: Ropivacaine 0.2% Injectable Solution - PENG block|DRUG: Control Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli Ileo Study
Status: COMPLETED
Conditions: Ileostomy - Stoma
Interventions: DIETARY_SUPPLEMENT: Broccoli & mustard seed soup|DIETARY_SUPPLEMENT: Broccoli soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Electromagnetic Field (RF-EMF) Effects on Brain Activity During Sleep and Waking in Healthy Elderly Women
Status: COMPLETED
Conditions: Nervous System Effects
Interventions: RADIATION: Exposure within the given regulatory limits for non-ionizing electromagnetic fields according to ICNIRP guidelines and German law
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sup-ER Splint for Children With Birth Related Brachial Plexus Injury
Status: WITHDRAWN
Conditions: Birth Related Brachial Plexus Injury|Obstetrical Brachial Plexus Palsy
Interventions: OTHER: Sup-ER Splint|OTHER: Currently accepted treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Alleviating the Symptoms of Photosensitive Migraine.
Status: UNKNOWN
Conditions: Migraine
Interventions: DEVICE: Lumishade® Active Lens|DEVICE: Lumishade® Sham Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Evaluation of Facial Swelling Post Impacted Lower Third Molars Surgery: RCT
Status: COMPLETED
Conditions: Swelling/ Edema|Impacted Third Molar Tooth
Interventions: PROCEDURE: Piezo-electric surgery of impacted lower third molars|PROCEDURE: Rotary bur surgery of impacted lower third molars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Ultrasound Guidance on Radiation Dose and Procedure Time in Lumbar Transforaminal Epidural Injection
Status: NOT_YET_RECRUITING
Conditions: Lumbar Disc Herniation|Radiculopathy Lumbar
Interventions: PROCEDURE: Fluoroscopy Guided Transforaminal Epidural Steroid Injection|PROCEDURE: Ultrasound Guided Transforaminal Epidural Steroid Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhalation of Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) for Autoimmune Pulmonary Alveolar Proteinosis (PAP)
Status: UNKNOWN
Conditions: Autoimmune Pulmonary Alveolar Proteinosis
Interventions: DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-19
Status: COMPLETED
Conditions: Alcohol Use Disorder|Family Members|Behavior, Addictive
Interventions: BEHAVIORAL: PartnerCHESS|BEHAVIORAL: ACHESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trastuzumab Administered Concurrently or Sequentially to Anthracycline-containing Adjuvant Regimen for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: concurrent|DRUG: sequential
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Solid Tumours
Interventions: PROCEDURE: Pharmacokinetic sampling|DRUG: Olaparib tablet dosing|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Assessing Covert Consciousness in Unresponsive Patients
Status: UNKNOWN
Conditions: Consciousness Disorders
Interventions: DEVICE: EEG recording|DRUG: Anesthetics, Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Laparoscopically-placed Adjustable Gastric Band for the Management of Obesity in Adolescent Patients
Status: TERMINATED
Conditions: Obesity
Interventions: DEVICE: LAP-BAND (Allergan, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer
Status: COMPLETED
Conditions: Oropharyngeal Dysphagia|Oropharyngeal Cancer
Interventions: BEHAVIORAL: Respiratory-Swallow Phase training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dinaciclib, Bortezomib, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Dinaciclib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ocrelizumab in Autoimmune Encephalitis
Status: TERMINATED
Conditions: Autoimmune Encephalitis
Interventions: DRUG: Ocrelizumab|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Subjects With Chronic Hepatitis B (CHB).
Status: RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: AHB-137 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Papillary Height Comparison in Microsurgically and Macrosurgically Placed Dental Implants
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: dental implant placement using magnifying loupes and microsurgical instruments|PROCEDURE: macrosurgical dental implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Febuxostat for Tumor Lysis Syndrome Prevention in Hematologic Malignancies
Status: COMPLETED
Conditions: Tumor Lysis Syndrome
Interventions: DRUG: Febuxostat|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Efficacy of Hydroxychloroquine and Azithromycine in Patients With COVID-19 and Hematological Malignancies (HYACINTHE)
Status: WITHDRAWN
Conditions: COVID19|Hematologic Malignancy
Interventions: DRUG: Hydroxychloroquine Sulfate 200 MG [Plaquenil]|DRUG: Azithromycin 250 MG Oral Capsule|DRUG: Placebo oral tablet|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker for Hereditary AngioEdema Disease
Status: COMPLETED
Conditions: C1 Esterase Inhibitor Deficiency|Angio Edema|C4 Deficiency|HAE|Hereditary Angioedema|Hereditary Angioedema Type II|Hereditary Angioedema Type III|Hereditary Angioedema Type I
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcomes of Autologous Bone Marrow Mononuclear Cell Administration in the Treatment of Neurologic Sequelea in Children With Spina Bifida
Status: COMPLETED
Conditions: Stem Cell Infusion
Interventions: COMBINATION_PRODUCT: Autologous bone marrow mononuclear cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Treating Patients With Myelofibrosis
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Drug-Resistant Childhood Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Locally Advanced Cancer|Metastatic Cancer
Interventions: DRUG: OMP-313M32|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Maternal Dadiah Supplementation During Pregnancy on Child Growth and Gastrointestinal Health Outcomes
Status: COMPLETED
Conditions: Gastrointestinal Microbiome|Immunoglobulin A|Growth; Stunting, Nutritional
Interventions: OTHER: Dadiah Pudding|OTHER: Pudding without Dadiah
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine in Postoperative Analgesia
Status: ENROLLING_BY_INVITATION
Conditions: Pain Management
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Toothpastes on Bacteria in Saliva
Status: COMPLETED
Conditions: Oral Health
Interventions: DRUG: Zinc-A toothpaste|DRUG: Zinc-B toothpaste|OTHER: Mineral water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Atazanavir 300 mg Capsule
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir + Ritonavir|DRUG: Atazanavir + Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Cervical Ripening in Premature Rupture of Membranes
Status: COMPLETED
Conditions: Pregnancy|Premature Rupture of Membranes|Preterm Premature Rupture of Membranes|Unfavorable Cervix
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: STimulation to Improve Auditory haLLucinations
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DEVICE: tACS (alpha)|DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Cerebral Oxygenation With Near Infrared Spectrophotometry (NIRS) at the Hypernatremic Dehydration in Newborn
Status: UNKNOWN
Conditions: HYPERNATREMIA
Interventions: DEVICE: INVOS 5100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Epigenetics Based Diagnosis of Diabetes in Saliva and Blood Samples
Status: UNKNOWN
Conditions: Prediabetic State|Diabetes Mellitus, Type 2|Ectopic Lipids|Epigenetics Based Modifications
Interventions: DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Saliva and blood samples|DIAGNOSTIC_TEST: Magnet Resonance Spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: DRUG: 18F-Fluoromisonidazole|DRUG: Carboplatin|PROCEDURE: Computed Tomography|PROCEDURE: Computed Tomography|RADIATION: External Beam Radiation Therapy|DRUG: Fludeoxyglucose F-18|RADIATION: Image-Guided Adaptive Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|PROCEDURE: Positron Emission Tomography|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamsulosin as Adjunctive Therapy After Extracorporeal Shock Wave Lithotripsy for Renal Stones
Status: COMPLETED
Conditions: Renal Stone
Interventions: PROCEDURE: Extracorporeal shock wave lithotripsy|DRUG: Diclofenac|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Centered Intervention to Prevent Tuberculosis Among Children Under Five Years Old
Status: COMPLETED
Conditions: Tuberculosis|Pediatric ALL|Behavior, Health
Interventions: BEHAVIORAL: Increasing the completion of IPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocarditis|Heart Failure|Myocardial Fibrosis|Vascular Inflammation
Interventions: DIAGNOSTIC_TEST: Cardiac Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ifosfamide With or Without Paclitaxel in Treating Patients With Advanced, Refractory, or Recurrent Cancer of the Uterus
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Visualization of the Extrahepatic biliaRy Tree Trial
Status: UNKNOWN
Conditions: Cholecystitis, Acute|Acute Cholangitis|Gallstone Pancreatitis|Choledocholithiasis|Cholecystolithiasis|Gallbladder Diseases|Biliary Tract Diseases|Digestive System Disease|Calculi|Pathological Conditions, Anatomical
Interventions: PROCEDURE: Laparoscopic Cholecystectomy with Fluorescent Cholangiography|PROCEDURE: Laparoscopic Cholecystectomy with White Light Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Ischemic Stroke, Acute
Interventions: OTHER: Left Atrial Appendage Occlusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Balance Auditory Vision Training (Bal-A-Vis-X) and Aerobic Training in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Bal-A-Vis-X training|OTHER: Aerobic Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: My Healthy Brain: Preserving and Promoting Brain Health Through Evidence-based Practices
Status: COMPLETED
Conditions: Aging|Mild Cognitive Impairment|Dementia|Old Age; Dementia|Cognitive Decline
Interventions: BEHAVIORAL: My Healthy Brain Version 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implantation of the HeartMate 3 in Subjects With Heart Failure Using Surgical SWIFT HM3 PMS
Status: COMPLETED
Conditions: Advanced Refractory Left Ventricular Heart Failure
Interventions: DEVICE: HeartMate 3 Left Ventricular Assist System (HM3 LVAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study to Investigate the Clinical Activity of IPI-504 in Patients With Hormone-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostatic Neoplasms|Cancer of the Prostate
Interventions: DRUG: IPI-504
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinician-Focused Nudging Intervention to Optimize Post-Surgical Prescribing
Status: COMPLETED
Conditions: Opioid Prescribing|Surgical Procedure, Unspecified
Interventions: BEHAVIORAL: Direct Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 14-3-3η Protein, Disease Activity and Bone Mineral Density, in Female Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoporosis
Interventions: DIAGNOSTIC_TEST: 14-3-3η Protein assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia
Status: RECRUITING
Conditions: Caregiver Burden|Depression|Cognitive Impairment
Interventions: BEHAVIORAL: SHARP - Physical and social activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Video and Traditional Laryngoscopy on Hemodynamic Response in Hypertensive and Normotensive Patients
Status: COMPLETED
Conditions: Intubation|Anesthesia|Hypertension
Interventions: DEVICE: Macintosh laryngoscopy|DEVICE: C-Mac Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Online Mindfulness-based Intervention to Prevent Chronic Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Chronic Pain|Pain Catastrophizing|Pain, Acute
Interventions: BEHAVIORAL: Online mindfulness-based cognitive therapy|BEHAVIORAL: Online standardized education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tracheal Colonization and Outcome After Major Abdominal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Neoplasms Malignant|Surgical Procedures, Operative|Stomach Neoplasms|Pancreatic Cancer, Adult
Interventions: OTHER: Tracheal aspirates and nasal smears were taken in all the patients. Laparotomies were performed in all patients.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Strategies to Increase Antenatal Iron and Folic Acid Supplementation and Malaria Prophylaxis
Status: UNKNOWN
Conditions: Antenatal Care
Interventions: BEHAVIORAL: Demand intervention|BEHAVIORAL: Supply intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EPPIC-Net: Novaremed Painful Diabetic Peripheral Neuropathy ISA
Status: RECRUITING
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: NRD135SE.1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies
Status: COMPLETED
Conditions: Sickle Cell Disease & Thalassemia
Interventions: DRUG: NiCord
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Idiopathic Perifoveal Telangiectasia (IPT) With Open-Label Anecortave Acetate (15mg.).
Status: COMPLETED
Conditions: Idiopathic Perifoveal Telangiectasia
Interventions: DRUG: anecortave acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 95% Effective Dose(ED95) of Remimazolam During Dexmedetomidine Pretreatment
Status: COMPLETED
Conditions: Lung Cancer|Anesthesia Induction
Interventions: DRUG: Dexmedetomidine|DRUG: Remimazolam tosilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Visual Involvement in Giant Cell Arteritis
Status: RECRUITING
Conditions: Giant Cell Arteritis|Visual Impairment|Central Retinal Artery Occlusion|Anterior Ischemic Optic Neuropathy|Paracentral Acute Middle Maculopathy|Posterior Ischemic Optic Neuropathy|Retinal Ischemia|Blindness|Visual Disorder
Interventions: DIAGNOSTIC_TEST: Fluorescein and Indocyanine green Angiography|DIAGNOSTIC_TEST: High-resolution Optical Coherence Tomography|DIAGNOSTIC_TEST: Angio-Optical Coherence Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Cognitive Function Study of EVP-6124 in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Central Nervous System Diseases|Cognition
Interventions: DRUG: EVP-6124|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corifollitropin Alfa Versus Daily rFSH in the Controlled Ovarian Stimulation of Poor Responders
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Corifollitropin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Autoimmune Diseases|Sjogren's Syndrome|Dry Eye
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Using Tranexamic Acid by Different Means to Reduce Blood Loss During Total Knee Replacement
Status: COMPLETED
Conditions: Blood Loss
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide Plus T-Cell Transplantation for Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Donor T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levodopa Concentration Profile With Stalevo 75/125 mg
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Stalevo (levodopa/ carbidopa/ entacapone)|DRUG: Sinemet (levodopa/carbidopa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Wine or Nutritional Supplement in Improving Appetite in Patients With Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: therapeutic nutritional supplementation|DIETARY_SUPPLEMENT: white wine|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium Sulfate as Adjuvant Analgesia and Its Effect on Opiate Use of Post-operative Transplant Patients in the Pediatric ICU
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety and Clinical Activity of GSK3326595 and Other Agents to Treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: GSK3326595|DRUG: 5-Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone, Body Composition,Insulin Sensitivity and Protein Metabolism in ESRD
Status: UNKNOWN
Conditions: ESRD
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medpulser Electroporation With Bleomycin Study to Treat Posterior Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head Neck Cancer
Interventions: COMBINATION_PRODUCT: Medpulser Electroporation with Bleomycin|PROCEDURE: Surgical Excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interstitial Lung Disease (ILD). Diagnostic Yield of Surgical Lung Biopsy Versus Cryobiopsy in the Same Surgical Stage.
Status: UNKNOWN
Conditions: Lung Diseases, Interstitial
Interventions: PROCEDURE: Lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Fluticasone Furoate/Vilanterol (FF/VI) Fixed Dose Combination (FDC) Compared to FF Alone in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF/VI via ELLIPTA DPI|DRUG: FF via ELLIPTA DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Efficacy of ZARNESTRA™ Combined With Tamoxifen in Patients With Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Tamoxifen|DRUG: Zarnestra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Short Multidisciplinary Education and Rehabilitation Program for Patients With Subacute and Chronic Low Back Pain (LBP) (LOMBAFAST)
Status: RECRUITING
Conditions: Non Specific Low Back Pain
Interventions: BEHAVIORAL: Education and rehabilitation associated with personalized follow-up|BEHAVIORAL: Reassuring messages and advices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Neoadjuvant Trastuzumab+Docetaxel+NPLD+/-Bevacizumab in Her2-pos. Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab, Docetaxel|DRUG: Trastuzumab, Docetaxel, Bevacizumab|DRUG: Trastuzumab+Docetaxel+NPLD|DRUG: Trastuzumab+Docetaxel+NPLD+Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
Status: TERMINATED
Conditions: Hemoglobinopathies|Anemia, Sickle Cell|Hemoglobin SC Disease|Thalassemia|Thalassemia Major
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: FK506|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain TV (Tissue Velocimetry) for Emergency Assessment of Acquired Brain Injury
Status: UNKNOWN
Conditions: Acquired Brain Injury|Traumatic Brain Injury|Stroke
Interventions: DIAGNOSTIC_TEST: Transcranial Tissue Doppler (TCTD)|DIAGNOSTIC_TEST: Brain MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Status: RECRUITING
Conditions: Dry Age-related Macular Degeneration
Interventions: BIOLOGICAL: RPESC-RPE-4W
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Design for Maxillofacial Prosthetics
Status: WITHDRAWN
Conditions: Prosthetic Treatment|Craniofacial Abnormalities|Maxillofacial Abnormalities
Interventions: DEVICE: 3D digital scanning for maxillofacial prosthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Repetitive Transcranial Magnetic Stimulation and Multi-modality Aphasia Therapy for Post-stroke Non-fluent Aphasia
Status: COMPLETED
Conditions: Stroke|Aphasia, Non-fluent
Interventions: DEVICE: 1Hz inhibitory rTMS|DEVICE: 1Hz sham rTMS|BEHAVIORAL: Multi-Modality Aphasia Therapy (M-MAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mindfulness-Based Intervention Versus Relaxation in Primary Care Burnout Providers.
Status: COMPLETED
Conditions: Burnout Syndrome
Interventions: BEHAVIORAL: 1- Mindfulness Intervention|BEHAVIORAL: 2- Relaxation Intervention|OTHER: 3- Wait List Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Proper Fractional Flow Reserve Criteria for Intermediate Lesions in the Era of Drug-eluting Stent
Status: TERMINATED
Conditions: Coronary Angiography|Drug-eluting Stents|Fractional Flow Reserve, Myocardial
Interventions: DEVICE: Cypher, Taxus or Endeavor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Verrucous Carcinoma of the Larynx|Stage IV Verrucous Carcinoma of the Oral Cavity|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Interventions: DRUG: ispinesib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients With Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma
Interventions: RADIATION: Metastasis directed therapy (MDT)|DRUG: Immunotherapy|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Nilotinib BE in Subjects With Early Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Nilotinib BE 84mg|DRUG: Nilotinib BE 112 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VRES Study in Two Phases to Monitor Cardiac Surgical Patients Following Discharge From ICU
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: Visensia Respiration Rate Estimation Service (VRES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Working Memory Training in Children With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Psychophysiology
Interventions: OTHER: Working memory training|OTHER: perceptual training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Manual Therapy in Patients With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Experimental: Study Group|OTHER: Active Comparator: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Liver Parenchyma Using Parametric T1 and T2 Magnetic Resonance Relaxometry
Status: COMPLETED
Conditions: Cardiomyopathy, Congestive|Pulmonary Hypertension|Constrictive Pericarditis|Cardiomyopathy, Dilated
Interventions: DIAGNOSTIC_TEST: T1 and T2 relaxometry of the liver parenchyma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Extension Study of Taliglucerase Alfa in Pediatric Subjects With Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: DRUG: Taliglucerase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Awake Nasal Fiber-optic Intubation of Severely Obese Patients in Lateral Position
Status: COMPLETED
Conditions: Anesthesia|Intubation;Difficult|Intubation; Difficult or Failed|Anesthesia Intubation Complication
Interventions: PROCEDURE: Fiberoptic intubation in supine position.|PROCEDURE: Fiberoptic intubation in lateral position.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alisertib in Treating Patients With Advanced or Metastatic Sarcoma
Status: COMPLETED
Conditions: Myxofibrosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Leiomyosarcoma|Recurrent Liposarcoma|Recurrent Malignant Peripheral Nerve Sheath Tumor|Recurrent Undifferentiated Pleomorphic Sarcoma|Stage III Soft Tissue Sarcoma AJCC v7|Stage IV Soft Tissue Sarcoma AJCC v7
Interventions: DRUG: Alisertib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Consumption on Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Nonmalignant Neoplasm|Paroxysmal Nocturnal Hemoglobinuria
Interventions: PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS
Status: COMPLETED
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing of Ischemic Leg Ulcers in Patients Treated With iSONIAzid
Status: WITHDRAWN
Conditions: Arterial Leg Ulcer
Interventions: DRUG: Isoniazid 300 milligram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Moderate Intensity Physical Activities on PK-guided EHL FVIII Concentrates Prophylaxis Severe HA Patients
Status: COMPLETED
Conditions: Hemophilia
Interventions: DRUG: combination between moderate to vigorous-intensity physical activities and pharmacokinetic-guided extended half-life FVIII concentrates prophylaxis|DRUG: pharmacokinetic-guided extended half-life FVIII concentrates prophylaxis alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MSC2364447C Phase 1b in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: MSC2364447C|DRUG: MSC2364447C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence Of Hemidiaphragmatic Paralysis After Usg Guided Low Dose Interscalene Brachial Plexus Block
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Interscalene Block with Ropivacaine Hcl 0.2% Inj Vil 10Ml|DRUG: IV diclofenac and IV paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Early Management on PAin and DEpression in Patients With PancreatoBiliary Cancer, EPADE-PB
Status: COMPLETED
Conditions: Pancreatic Cancer|Biliary Tract Cancer|Cancer Pain|Depression
Interventions: OTHER: Early Palliative care integrated with usual oncologic care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mirror Therapy on Cerebral Re-organization, Functional Motor Skills, and Quality of Life in Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy
Interventions: OTHER: control group|OTHER: intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures
Status: RECRUITING
Conditions: Cardiac Surgery|Older Adults|Depression|Anxiety
Interventions: BEHAVIORAL: Behavioral activation|OTHER: Medication optimzation|OTHER: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Gene
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia|Acute Lymphocytic Leukemia|Acute Leukemias
Interventions: DRUG: EPZ-5676
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Long-term Clinical Response to BoNT in Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: CC BoNT/A|BIOLOGICAL: CF BoNT/A|BIOLOGICAL: CF to CC BoNT/A|BIOLOGICAL: CC to CF BoNT/A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-Peritoneal Local Anaesthesia After Cytoreductive Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT