pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chlorobutanol, Potassium Carbonate, and Irrigation in Cerumen Removal
Status: COMPLETED
Conditions: Ear Infection|Hearing Loss|Vertigo
Interventions: DRUG: drops intilation (Taponoto ® )|DRUG: drops intilation (Otocerum®)|DRUG: drops intilation (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Mucositis Pain in Cancer Care
Status: WITHDRAWN
Conditions: Mucositis|Pain|Leukemia
Interventions: PROCEDURE: Real Acupuncture|PROCEDURE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance of a Silicone Hydrogel Lens With Use of FID 114675A
Status: COMPLETED
Conditions: Contact Lens Fit|Myopia
Interventions: DEVICE: FID 114675A multi-purpose disinfecting solution (MPDS)|DEVICE: renu fresh Multi-Purpose Solution (MPS)|DEVICE: Galyfilcon A contact lenses (Acuvue Advance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: DRUG: Ezerosu(monolayer tablet)|DRUG: Ezerosu(double layer tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Status: RECRUITING
Conditions: Fear|GAD|Emotional Memory|PTSD
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Endometriosis With 16α-(18)F-fluoro-17β-estradiol ([F-18] FES) PET/MRI
Status: WITHDRAWN
Conditions: Endometriosis
Interventions: DRUG: F-18 FES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Temporary Gastric Electrical Stimulation for Drug Refractory Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DEVICE: Gastric Electrical Stimulator, Enterra, Medtronics, Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suicide Gene Therapy for Donor Lymphocytes Infusion After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematological Malignancy
Interventions: BIOLOGICAL: donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravital Microscopy for Identifying Tumor Vessels in Patients With Stage IA-IV Melanoma That is Being Removed by Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IA Skin Melanoma|Stage IB Skin Melanoma|Stage IIA Skin Melanoma|Stage IIB Skin Melanoma|Stage IIC Skin Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: PROCEDURE: Diagnostic Microscopy|DRUG: Fluorescein Sodium Injection|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lybridos in Pre- and Postmenopausal Women With Hypoactive Sexual Desire Disorder Due to Maladaptive Activation of Sexual Inhibitory Systems
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Placebo|DRUG: Testosterone|DRUG: Buspirone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subacute and Chronic, Non-specific Back and Neck Pain: Cognitive-behavioral Rehabilitation vs. Traditional Primary Care
Status: COMPLETED
Conditions: Back Pain|Neck Pain
Interventions: BEHAVIORAL: Cognitive-behavioral rehabilitation|BEHAVIORAL: Traditional primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effectiveness of the NECT Program
Status: UNKNOWN
Conditions: Schizophrenia|Bipolar Disorder|Borderline Personality Disorder|Social Function|Self-stigma
Interventions: OTHER: Psychiatric interview|OTHER: Clinical, diagnostic and functional evaluation|OTHER: neuropsychological assessment|OTHER: NECT PROGRAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema
Status: COMPLETED
Conditions: Macular Edema|Diabetic Macular Edema|Neovascular Age-related Macular Degeneration|Retinal Vein Occlusions
Interventions: DRUG: LKA651|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Movement Simulation Techniques and Therapeutic Exercise in Young Nulliparous Women
Status: RECRUITING
Conditions: Motor Imagery|Action Observation|Therapeutic Exercise
Interventions: BEHAVIORAL: Therapeutic exercise plus motor imagery|BEHAVIORAL: Therapeutic exercise plus action observation|BEHAVIORAL: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Luminal-type Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Lvonescimab (AK112)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Need of Fiberoptic Bronchoscopy for Placing an Endobronchial Blocker
Status: COMPLETED
Conditions: Neoplasms, Pulmonary|Thoracic Diseases
Interventions: PROCEDURE: conventional|PROCEDURE: auscultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Insulin Modelling Based on Plasma Glucose Measures Via a Minimally-Invasive Glucose Sensor
Status: COMPLETED
Conditions: PreDiabetes
Interventions: OTHER: Single dose of 75 grams glucose in 200ml water
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus Bacteraemia
Status: NOT_YET_RECRUITING
Conditions: Staphylococcus Aureus Bacteremia|Staphylococcus Aureus Septicemia|Sepsis Bacterial|Bloodstream Infection|Staph Sepsis|Staphylococcus Aureus Infection|Sepsis
Interventions: DIAGNOSTIC_TEST: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo
Status: TERMINATED
Conditions: Wounds|Local Anesthesia
Interventions: DRUG: Lidocaine solution ("A")|DRUG: Saline solution ("B")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optical Monitoring With Near-Infrared Spectroscopy for Spinal Cord Injury Trial
Status: RECRUITING
Conditions: Acute Spinal Cord Injury|Spinal Cord Injuries
Interventions: DEVICE: Near Infra-Red Spectroscopy (NIRS) Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Bisantrene Combination for Resistant AML
Status: RECRUITING
Conditions: Myelogenous Leukemia, Acute
Interventions: DRUG: Bisantrene|DRUG: Fludarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab and Gemcitabine in Relapsed Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of APSLXR in Patients Presenting Vertigo of Vestibular Origin or Meniere's Disease
Status: WITHDRAWN
Conditions: Meniere Disease|Vertigo|Vertigo Vestibular
Interventions: DRUG: APSLXR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-0431/ONO-5435 Phase III Clinical Trial - Insulin Add-on Study for Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-0431/ONO-5435|DRUG: MK-0431/ONO-5435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of 3D Printing Guide Plate in Endoscopic Spinal Surgery
Status: UNKNOWN
Conditions: Lumbar Disc Herniation|Lumbar Spinal Stenosis|Radicular Pain|Low Back Pain
Interventions: OTHER: 3D printing guide plate|OTHER: Conventional guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda
Status: COMPLETED
Conditions: Malaria in Pregnancy|HIV Infections
Interventions: DRUG: sulfadoxine-pyrimethamine intermittent preventive treatment|DRUG: chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Microplasmin in for Non-Surgical Treatment of Focal Vitreomacular Adhesion
Status: COMPLETED
Conditions: Focal Vitreomacular Adhesion
Interventions: DRUG: Microplasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: M9466|DRUG: Tuvusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD5 CAR T Cells for Relapsed/Refractory T Cell Malignancies
Status: UNKNOWN
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Non-Hodgkin Lymphoma
Interventions: DRUG: anti-CD5 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making
Status: COMPLETED
Conditions: Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Cirrhosis|Colon Carcinoma|Lung Cancer|Chronic Kidney Disease
Interventions: OTHER: Values Inventory (VI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multicenter, Open, Prospective, 48 Weeks, Observational Study ,Evaluate the Safety and Efficacy of Nephoxil Capsule
Status: RECRUITING
Conditions: Hyperphosphatemia
Interventions: DRUG: the low-dose group (1.5 g/day) or the standard-dose group (4 g/day)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection
Interventions: BIOLOGICAL: Quadrivalent Meningococcal Polysaccharide (A, C, Y, and W-135) Tetanus Protein Conjugate|BIOLOGICAL: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus B Conjugate (Tetanus Toxoid Conjugate) Vaccine Combined (DTaP-IPV/Hib combined)|BIOLOGICAL: M-M-RII-Measles, Mumps, and Rubella Virus Vaccine Live|BIOLOGICAL: Varicella Virus Vaccine Live|BIOLOGICAL: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein)|BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine (Diphtheria CRM197 Protein)|BIOLOGICAL: Rotavirus Vaccine|BIOLOGICAL: Hepatitis B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of TF-TAVR on Emotional Status, Quality of Life, Frailty and Inflammation
Status: TERMINATED
Conditions: Aortic Valve Stenosis|Clinical Trial|Depression|Frail Elderly Syndrome|Inflammation
Interventions: DIAGNOSTIC_TEST: Geriatric assessment|DIAGNOSTIC_TEST: Psychiatric assessment|DIAGNOSTIC_TEST: Inflammatory assessment|DIAGNOSTIC_TEST: Cardiological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction
Status: COMPLETED
Conditions: Normal Non-fluency
Interventions: DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Stendo Pulsating Suit on Microcirculation and Endothelial Function in Diabetic Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DEVICE: Verum Stendo session on V1 and Phantom Stendo session on V2|DEVICE: Phantom Stendo session on V1 and Verum Stendo session on V2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Virtual Touch Tissue Imaging Quantification (VTIQ - 2D-SWE) in the Assessment of BI-RADS® 3 and 4 Lesions
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: Ultrasound- Virtual Touch Tissue Imaging Quantification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Online Mindfulness-based Tic Reduction (Phase Two)
Status: COMPLETED
Conditions: Tourette Syndrome|Persistent Tic Disorder
Interventions: BEHAVIORAL: Mindfulness-based Intervention for Tics|BEHAVIORAL: Tic Information and Coping Strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: Donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention, Randomized, Double-Blinded, Placebo-Controlled, Parallel Assignment, Safety/Efficacy Study
Status: COMPLETED
Conditions: Traveler's Diarrhea
Interventions: BIOLOGICAL: Biological: heat-labile enterotoxin of E. coli (LT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of Biologic Signatures in Crohn's Patients Undergoing Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Crohn Disease
Interventions: PROCEDURE: Kono-S anastomosis (KSa)|PROCEDURE: Side-to-side anastomosis (SSa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Determination of Heart Rate in Infants Needing Resuscitation at Birth
Status: COMPLETED
Conditions: Perinatal Asphyxia
Interventions: OTHER: Heart rate assessment (stethoscope)|OTHER: Heart assessment (umbilical cord palpation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Product 1|OTHER: Product 2|OTHER: Product 3|OTHER: Product 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Mycamine® in Children With Fungal Infections to Evaluate Safety and Blood Levels of the Drug
Status: COMPLETED
Conditions: Oropharyngeal Candidiasis|Candidemia|Invasive Candidiasis|Esophageal Candidiasis
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Trial Standard of Care Vascular Access Strategies for (Neo)Adjuvant Trastuzumab-based Breast Cancer Treatment.
Status: COMPLETED
Conditions: Breast Cancer|Cancer
Interventions: DEVICE: PICC|DEVICE: PORT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dietary Green Tea Confection For Resolving Gut Permeability-Induced Metabolic Endotoxemia In Obese Adults
Status: UNKNOWN
Conditions: Obesity|Endotoxemia|Inflammation
Interventions: OTHER: Green Tea Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Expanding Knowledge About and Evaluating Services for Incarcerated Pregnant and Postpartum Women in Arkansas
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Problems in Pregnancy|Childbirth Problems|Maternal Care Patterns|Quality of Life|Emotional Stress|Health Care Acceptability|Health Risk Behaviors|Parent-Child Relations
Interventions: BEHAVIORAL: Childbirth support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Corneal Epithelial Allograft From Living-related Donor for LSCD
Status: COMPLETED
Conditions: Limbal Stem Cell Deficiency
Interventions: PROCEDURE: Corneal epithelial allograft|PROCEDURE: Limbal conjunctival allograft|DEVICE: Femtosecond laser|DEVICE: Diamond knife
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into the Efficacy of Herpecin L at Reducing the Frequency and Severity of Cold Sores
Status: COMPLETED
Conditions: Cold Sores
Interventions: OTHER: Herpecin L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dapagliflozin, Cardio-Metabolic Risk Factors and Type-2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
Status: COMPLETED
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: C-Leg 4|DEVICE: C-Leg 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Administration in Ketoacidosis (DRINK)
Status: NOT_YET_RECRUITING
Conditions: Diabetic Keto-acidosis
Interventions: DRUG: Fluid resuscitation with isotonic saline only|DRUG: Fluid resuscitation with Ringer Lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Family Connections" for Caregivers of People With Eating Disorders and Personality Disorders.
Status: UNKNOWN
Conditions: Relatives
Interventions: BEHAVIORAL: Family Connections for relatives of people with eating disorders and personality disorders|BEHAVIORAL: Optimized Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mineralized and Partial Demineralized Dentin Graft Compared to FDBA
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Freeze-Dried Bone Allograft control|PROCEDURE: Mineralized Dentin Graft|PROCEDURE: Partial-Demineralized Dentin Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)
Status: COMPLETED
Conditions: Palmoplantar Pustulosis
Interventions: DRUG: RIST4721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Bowel Stimulation Before Loop Ileostomy Closure Reduce Postoperative Ileus?
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Bowel stimulation|DRUG: Nestle Resource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Trial Of Disulfiram, Naltrexone And Acamprosate In The Treatment Of Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Disulfiram|DRUG: Acamprosate|DRUG: Naltexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caduet and TLC Intervention in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Therapeutic Lifestyle Change|DRUG: Caduet Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PPAR-gamma: a Novel Therapeutic Target for Asthma?
Status: TERMINATED
Conditions: Asthma
Interventions: OTHER: placebo|DRUG: IMP Pioglitozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acandis Credo Intracranial Stent for Unsuccessful Recanalization After Thrombectomy (ACUTE)
Status: TERMINATED
Conditions: Acute Ischemic Stroke|Intracranial Stenosis
Interventions: DEVICE: Treatment with Credo® stent together with the NeuroSpeed® PTA balloon catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IMX-110 in Combination With Tislelizumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: IMX-110 combined with Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Quinapril Hydrochloride 20 mg and Hydrochlorothiazide 25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: fixed-dose combination of quinapril 20 mg and hydrochlorothiazide 25 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dance Therapy as an Alternative for Cardiac Rehabilitation in Women Population
Status: COMPLETED
Conditions: Cardiac Risk Factors|Cardiovascular Diseases
Interventions: OTHER: Conventional Exercise-based Cardiac Rehabilitation Session|OTHER: Dance-based Cardiac Rehabilitation Session
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPO for Postop Delirium in Elderly Patients
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: Erythropoietin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Enzymatic Activity of Lymphocyte Dihydropyrimidine Dehydrogenase DPD in the Blood as a Predictive and Prognostic Factor in Patients With Digestive Cancer in the First or Second Metastatic Line
Status: UNKNOWN
Conditions: Metastatic or Locally-advanced Digestive Cancer
Interventions: DIAGNOSTIC_TEST: lymphocyte DPD dosage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy & Tolerability of a Specific Plantain,Thyme and Honey Cough Syrup vs Placebo in Child Cough Due to Common Cold
Status: COMPLETED
Conditions: Cough
Interventions: DEVICE: Cough syrup for adults and children|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cocoa Consumption in Cardiovascular and Immune Parameters
Status: TERMINATED
Conditions: Arterial Hypertension
Interventions: DIETARY_SUPPLEMENT: Dark chocolate|DIETARY_SUPPLEMENT: White chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions: DRUG: Cisplatin|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Onalespib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Secondary Acute Myeloid Leukemia
Interventions: PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|DRUG: fludarabine phosphate|RADIATION: total-body irradiation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
Status: COMPLETED
Conditions: Sacroiliac Strain|Low Back Pain
Interventions: PROCEDURE: Immediate corrective exercises|DEVICE: Immediate use of pelvic support belt|OTHER: Delayed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Coconut and Sunflower Seed Oil Derived Isosorbide Diseters and Colloidial Oatmeal
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: OTHER: Isosorbide Diester Moisturizer|OTHER: Control Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STEP Together: An Effectiveness-Implementation Study of Social Incentives and Physical Activity
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity
Interventions: BEHAVIORAL: Social Incentive Gamification|BEHAVIORAL: Social Goals through Incentives to Charity|BEHAVIORAL: Daily Performance Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of PGI2 Analogue Use on the Development of Chronic Allograft Nephropathy
Status: COMPLETED
Conditions: Chronic Allograft Nephropathy
Interventions: DRUG: prostaglandin I2 analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FOTO: Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment Versus Continuous Treatment
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Intermitent Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cediranib|DRUG: FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin)|DRUG: XELOX (Capecitabine and Oxaliplatin)|DRUG: Cediranib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Based TPX Neoadjuvant Chemotherapy for NPC Patients: a Dose-escalation Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Cancer
Interventions: DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK/PD & Preliminary Efficacy of SKL27969 in Advanced Solid Tumors Patients
Status: TERMINATED
Conditions: Advanced Solid Tumor
Interventions: DRUG: SKL27969
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alcohol on ABCA1 Expression and Lipid Metabolism
Status: TERMINATED
Conditions: Type 2 Diabetes|Heart Disease
Interventions: DIETARY_SUPPLEMENT: Red Wine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Total Versus Subtotal Hysterectomy:a Randomised, Prospective Multicentre Study of the Effect on Urinary, Sexual and Bowel Function
Status: COMPLETED
Conditions: Hysterectomy
Interventions: PROCEDURE: Total abdominal hysterectomy|PROCEDURE: Subtotal abdominal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Aspiration Thrombectomy During Carotid Stenting
Status: UNKNOWN
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Emboshield NAV6® embolic protection system (Abbott Vascular, Santa Clara, CA)|DEVICE: Emboshield NAV6® embolic protection system (Abbott Vascular, Santa Clara, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Toripalimab in Adjuvant Therapy After Resection of High-risk Renal Cancer Tumors
Status: RECRUITING
Conditions: High-risk Renal Cell Carcinoma
Interventions: DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Multiple Assignment Randomized Trial for Bipolar Depression
Status: NOT_YET_RECRUITING
Conditions: Bipolar I Disorder|Depression
Interventions: DRUG: Cariprazine|DRUG: Aripiprazole/Escitalopram combination|DRUG: Quetiapine|DRUG: Lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Nutrition Program in Improving Physical Activity and Dietary Behavior in Non-Active, Overweight, or Obese Latinas
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Nutritional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Antipsychotics on Brain Insulin Action in Females
Status: RECRUITING
Conditions: Insulin Resistance|Menstrual Cycle|Type 2 Diabetes|Antipsychotics
Interventions: DRUG: Olanzapine 2.5Mg Oral Tablet|DRUG: Placebo|DRUG: Insulin Lispro 100 UNT/ML|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Abuse Potential of Intravenous Remimazolam Compared to Midazolam and Placebo in Recreational CNS Depressant Users
Status: COMPLETED
Conditions: Abuse, Drug
Interventions: DRUG: Remimazolam|DRUG: Midazolam|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High Dose Dual Therapy, Sequential Therapy and Triple Therapy in H. Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Infection
Interventions: DRUG: high dose dual therapy|DRUG: sequential therapy|DRUG: clarithromycin-based triple therapy|DRUG: levofloxacin-based triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Xylitol|DRUG: Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage III Colon Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Stage III Colon Cancer
Interventions: DRUG: leucovorin calcium|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer
Status: RECRUITING
Conditions: Caregiver Burden|Caregiver Burnout|Caregiver Stress Syndrome
Interventions: BEHAVIORAL: Meaning-Centered Psychotherapy for Caregivers|BEHAVIORAL: Supportive Psychotherapy for Caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Forearm Nerve Blocks on Pain-free Tourniquet Time Compared to Local Anesthetic for Awake Hand Surgery
Status: NOT_YET_RECRUITING
Conditions: Fracture Fixation, Internal|Metacarpal Fracture|Finger Fracture|Anesthesia, Local|Tendon Injury - Hand
Interventions: PROCEDURE: Forearm nerve block|PROCEDURE: Local anesthetic infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraosseous With Intra-articular Injection of Platelet Rich Plasma in Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: PRP|DRUG: HA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biochemotherapy With Temozolomide for Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Temozolomide|DRUG: Velban|DRUG: Cisplatin|DRUG: Interleukin-2|DRUG: Intron-A|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Pegylated interferon (PEG-IFN) alfa-2a, 180 mcg|DRUG: Pegylated interferon (PEG-IFN) alfa-2a, 135 mcg|DRUG: Lamivudine (LAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to CMDHA0101 as Compared to PowerFill® for Temporary Penile Enhancement
Status: COMPLETED
Conditions: Small Penis|Penile Enhancement
Interventions: DEVICE: CMDHA0101|DEVICE: PowerFill®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating TEPEZZA® Treatment in Patients With Chronic (Inactive) Thyroid Eye Disease
Status: COMPLETED
Conditions: Thyroid Eye Disease|Chronic (Inactive) Thyroid Eye Disease
Interventions: BIOLOGICAL: TEPEZZA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Resistant Hypertension by Renal Sympathetic Denervation in Patients Undergoing Dialysis Therapy
Status: TERMINATED
Conditions: Hypertension Secondary to Renal Disease
Interventions: PROCEDURE: Renal nerve denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Mitral Regurgitation Repair
Status: UNKNOWN
Conditions: Mitral Valve Insufficiency|Mitral Valve Prolapse|Chronic Mitral Disease|Mitral Regurgitation|Mitral Valve Disease|Degenerative Mitral Valve Disease|Myxomatous Mitral Valve Degeneration|Ventricular Remodeling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mouthwashes During Orthodontic Treatment
Status: UNKNOWN
Conditions: Gingivitis
Interventions: DRUG: Essential oils|DRUG: Cetylpyridinium Chloride 0.7 mg/ml|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Smith & Nephew's European Trufit Study
Status: TERMINATED
Conditions: Defect of Articular Cartilage
Interventions: DEVICE: Trufit CB (Cartilage Bone) Implant|PROCEDURE: Microfracture if the knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant/-Sensitive Staphylococcus Aureus (MRSA/MSSA)
Status: COMPLETED
Conditions: Nasal Carriers MRSA
Interventions: DRUG: LTX-109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Galantamine|BEHAVIORAL: Computer Assisted Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrogen Peroxide Trial to Investigate the Efficacy of 30%H2O2 as a Topical Application Before Definitive Treatment
Status: UNKNOWN
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma of Skin Differentiated
Interventions: DRUG: Hydrogen Peroxide 30 % Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acquisition of Daily Living Skills in Autistic Children: Comparison Between QR Code and a Human Operator
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Video modeling by scanning Qr code|BEHAVIORAL: Modeling traditional method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Extracranial Malignant Solid Neoplasm|Radiotherapy|Immune Checkpoint Blockade|Resistance to Immunotherapy
Interventions: RADIATION: Intestinal Low Dose Radiotherapy-1Gy|RADIATION: Intestinal Low Dose Radiotherapy-2Gy|RADIATION: Intestinal Low Dose Radiotherapy-3Gy|DRUG: PD-1 Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BIOLOGICAL: MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Dapagliflozin With and Without Saxagliptin on Albuminuria, and to Investigate the Effect of Dapagliflozin and Saxagliptin on HbA1c in Patients With Type 2 Diabetes and CKD
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus, CKD and Albuminuria
Interventions: DRUG: Dapagliflozin 10 mg|DRUG: Saxagliptin 2.5 mg|DRUG: Matching Placebo for Dapagliflozin 10 mg and Saxagliptin 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IPI-504 in NSCLC Patients With ALK Translocations
Status: TERMINATED
Conditions: Lung Cancer|Stage IIIb Lung Cancer|Stage IV Lung Cancer
Interventions: DRUG: IPI-504
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune System Suppression With Alemtuzumab and Tacrolimus in Liver Transplantation Patients
Status: COMPLETED
Conditions: Liver Disease|Liver Transplantation
Interventions: DRUG: Alemtuzumab|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|PROCEDURE: Liver transplant|PROCEDURE: Immunosuppression withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Decreasing Kinetics of the Leptospiremia During Antibiotic Treatment of Leptospirosis in Martinique
Status: UNKNOWN
Conditions: Leptospirosis
Interventions: OTHER: Quantitative PCR performed at H0 , H24, H48 , H72, 7th day and 14th day
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botulinum Toxin Type A Block of the Otic Ganglion in Chronic Cluster Headache: Safety Issues
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: Botulinum Toxin Type A 25 IU|DRUG: Botulinum Toxin Type A 12.5 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Persistence Study to Assess a Booster Dose of GSK Biologicals' Hib-MenC
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: Haemophilus influenzae type b- and meningococcal (vaccine)|BIOLOGICAL: Infanrix™ penta|BIOLOGICAL: Infanrix™ hexa|BIOLOGICAL: Engerix-B|BIOLOGICAL: NeisVac-C™|BIOLOGICAL: Infanrix™ IPV/HIB|BIOLOGICAL: Meningitec™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Anesthetic Methods on Hepatic Cancer Cell Function in Vitro
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: general anesthesia|PROCEDURE: local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of AB-LIFE Probiotic Plus Monacolin K to Reduce Blood Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: AB-LIFE with Monacolin K|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT