pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brain Machine Interface Control of an Robotic Exoskeleton in Training Upper Extremity Functions in Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: MAHI EXO-II exoskeleton augmented with BMI system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Ambu ® aScope® for Tracheal Intubation in Difficult Airways
Status: COMPLETED
Conditions: Surgical Intervention|Endotracheal Intubation
Interventions: DEVICE: Ambu ® aScope®|DEVICE: a conventional reusable fiberscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC)
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Compare The Putative Anxiolytic Effect Of 2 New Drugs In Subjects With Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Phobia
Interventions: DRUG: GSK561679 tablet|DRUG: GW876008 tablet|DRUG: alprazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized Influenza Vaccine Evaluation of Immune Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: Standard IIV4|BIOLOGICAL: Recombinant|BIOLOGICAL: Cell-culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Relapse From MRD Negativity as Indication for Treatment (REMNANT) Study
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Early treatment of relapse with carfilzomib, dexamethasone, daratumumab|DRUG: Standard treatment of relapse with carfilzomib, dexamethasone, daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Algorithm-Guided Transfusions in Cardiac Surgery Patients for Reduction of Drainage Blood Losses
Status: TERMINATED
Conditions: Chest Tube Output|Allogeneic Blood Transfusions
Interventions: OTHER: Point of Care Coagulation Monitoring Guided Transfusion Algorithm|OTHER: standard coagulation monitoring guided transfusion algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse Phototherapy With Super Light-emitting Diode(Super-LED) for Hyperbilirubinemia in Term and Late Preterm Infants
Status: UNKNOWN
Conditions: Neonatal Hyperbilirubinemia
Interventions: DEVICE: Phototherapy|DEVICE: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With Primary Refractory or Relapsed Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Adult Hodgkin Lymphoma
Interventions: BIOLOGICAL: basiliximab|DRUG: carmustine|DRUG: etoposide|DRUG: cytarabine|DRUG: melphalan|OTHER: pharmacological study|OTHER: laboratory biomarker analysis|PROCEDURE: autologous hematopoietic stem cell transplantation|BIOLOGICAL: yttrium Y 90-labeled basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin in the Treatment of Full Thickness Palatal Wounds
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Palatal wound bandage with PRF|PROCEDURE: Palatal wound bandage with Gelatine Sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy|Motor Deficits
Interventions: BEHAVIORAL: Pediatric Constraint-Induced Movement therapy|BEHAVIORAL: Conventional pediatric motor rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia
Status: COMPLETED
Conditions: Community-acquired Bacterial Pneumonia
Interventions: DRUG: Solithromycin|DRUG: Moxifloxacin|OTHER: Placebo to match solithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Assessment and Treat Compliance in Hypertension Education Trial
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia
Interventions: BEHAVIORAL: Knowledge of Cardiovascular Risk Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
Status: RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8|Metastatic Basal Cell Carcinoma|Metastatic Carcinoma in the Skin|Metastatic Melanoma|Metastatic Merkel Cell Carcinoma|Metastatic Skin Squamous Cell Carcinoma|Unresectable Basal Cell Carcinoma|Unresectable Melanoma|Unresectable Merkel Cell Carcinoma|Unresectable Skin Squamous Cell Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Kidney Biopsy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|DRUG: Prednisone|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study
Status: RECRUITING
Conditions: Postoperative Fatigue|Postoperative Sleep Disturbances|Surgical Stress Response
Interventions: DRUG: Placebo|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone on Reduction of Macular Thickness in Diabetic Patients, a Randomized Clinical Trial
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreous Dexamethasone Solution 4mg/ml - vol 0,01 ml|DRUG: Intravitreous Dexamethasone Solution 4mg/ml - vol 0,03 ml|DRUG: Intravitreous Dexamethasone Solution 4mg/ml - vol 0,05 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acute Intake of Ketones on Performance in Professional Road Cyclists
Status: COMPLETED
Conditions: Ketoses, Metabolic|Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone monoester|DIETARY_SUPPLEMENT: Control product consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pressure Support Ventilation Versus Continuous Positive Air Way Pressure (CPAP) Using I Gelin Adult Patients,
Status: UNKNOWN
Conditions: Ventilator Lung
Interventions: DEVICE: the first 15 minutes with pressure support ventilation|DEVICE: the following 15 minutes ventilation will be changed to continous positive air way pressureCPAP mode|DEVICE: i gel air way
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy
Status: COMPLETED
Conditions: Oral Neoplasm|Pharynx Cancer|Larynx Cancer
Interventions: DEVICE: Tritube|DEVICE: Standard enditracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BuEAM Conditioning for Autologous Stem Cell Transplantation (ASCT) to Treat Diffuse Large B Cell Lymphoma (DLCBL)
Status: UNKNOWN
Conditions: Non Hodgkin's Lymphoma
Interventions: DRUG: Busulfan, Etoposide, Cytarabine, Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Preventing Cytomegalovirus in Healthy Participants
Status: COMPLETED
Conditions: Nonneoplastic Condition
Interventions: BIOLOGICAL: PADRE-CMV fusion peptide vaccine|BIOLOGICAL: tetanus-CMV fusion peptide vaccine|DRUG: agatolimod sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Management of HIV Infected Adults at Risk for Kidney Complications in Nigeria
Status: SUSPENDED
Conditions: HIV/AIDS|Albuminuria|Kidney Diseases|Genetic Predisposition
Interventions: DRUG: Lisinopril|OTHER: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD
Status: WITHDRAWN
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DEVICE: EsophyX™ system with SerosaFuse fasteners
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Red Blood Cell Transfusion Triggers in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: OTHER: Red blood cell Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extension Study of IMO-8400 in Patients With Waldenström's Macroglobulinemia Who Completed Study 8400-401
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: IMO-8400 0.6 mg/kg/wk or 1.2 mg/kg twice weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Volume in Young Patients With Major Depression Before and After Combined Antidepressive Therapy
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Mirtazapine|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety of Cedirogant and How Cedirogant Moves Through the Body in Adult Participants With Mild, Moderate and Severe Hepatic Impairment
Status: TERMINATED
Conditions: Hepatic Impairment
Interventions: DRUG: Cedirogant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinomas
Interventions: RADIATION: Reduced Dose Radiation|RADIATION: Standard Dose Radiation|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence Intervention to Promote Optimal Use of Insulin Pumps in Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Adherence behaviors and recommendations for improvement.|BEHAVIORAL: Adherence behavior that needs improvement is targeted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thera Band Exercises on Adhesive Capsulitis Post Mastectomy
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Exercise|OTHER: Thera band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose Aspirin
Status: COMPLETED
Conditions: Prevention
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: SL-172154
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tisseel® as a Reinforcement of Esophagojejunal Anastomoses
Status: UNKNOWN
Conditions: Gastric Cancer|Anastomotic Leak
Interventions: DRUG: Tisseel|DEVICE: No Tisseel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Coronary Intervention Biotronik Orsiro DES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetuin-A, a Promising Serum Biomarker for Diagnosis of Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DEVICE: abdominal U/S|DEVICE: Fibroscan with Controlled Attenuated Parameter (CAP scan):
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Humans
Status: COMPLETED
Conditions: Opiate Addiction
Interventions: DRUG: Cannabidiol 400|DRUG: Cannabidiol 800|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Synovitis|Osteoarthritis|Joint Diseases|Muskuloskeletal Diseases
Interventions: DRUG: Chondroitin sulphate (Condrosan)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Liver and Intrahepatic Bile Duct Disorder|Metastatic Malignant Neoplasm in the Liver|Primary Malignant Liver Neoplasm
Interventions: PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|DRUG: Gadobutrol|DRUG: Gadoxetate Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Status: RECRUITING
Conditions: Osteoarthritis|Tendinopathy|Arthropathy
Interventions: DRUG: Triamcinolone injection to the shoulder, elbow, wrist, or hand|DRUG: Ketorolac injection to the shoulder, elbow, wrist, or hand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing Human Thyroglobulin to People With Thyroglobulin Expressing Thyroid Cancer
Status: WITHDRAWN
Conditions: Metastatic Thyroid Cancer
Interventions: DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Anti-Thyroglobulin mTCR PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Alectinib Treatment by Detection of ALK Translocations in Serial Blood Samples From Non-Small Cell Lung Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Lung Cancer|ALK Gene Mutation|Resistance, Disease|Mutation
Interventions: DRUG: Alectinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug-Drug Interaction Study Between DWC20155 / DWC20156 and DWC20161 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Co-administration of DWC20155/DWC20156|DRUG: DWC20161
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Plane Block Versus Retrolaminar Plane Block
Status: COMPLETED
Conditions: Post Operative Pain|Analgesia
Interventions: PROCEDURE: retrolaminar block|PROCEDURE: ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telephone Counseling and Numberless Scales to Overcome Barriers to Adolescent Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Numberless BDS|BEHAVIORAL: Digital Scale|BEHAVIORAL: Modified Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-dose Gated CT Validity for the Evaluation of Ascendant Aortic Aneurysm.
Status: COMPLETED
Conditions: Ascendant Aortic Aneurysm
Interventions: OTHER: Modified Low-dose, EKG-gated CT without contrast for the evaluation of aortic aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of Vasomotion of People With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Paraplegia
Interventions: BEHAVIORAL: Cold environment participants with spinal cord injury|BEHAVIORAL: Thermoneutral environment participants with spinal cord injury|BEHAVIORAL: Warm environment participants with spinal cord injury|BEHAVIORAL: Cold environment healthy male participants|BEHAVIORAL: Thermoneutral environment healthy male participants|BEHAVIORAL: Warm environment healthy male participants|BEHAVIORAL: Cold environment healthy female participants|BEHAVIORAL: Thermoneutral environment healthy female participants|BEHAVIORAL: Warm environment healthy female participants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Dye-less Cystoscopy in Assessing Urinary Tract Integrity During Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy|Cystoscopy
Interventions: DIAGNOSTIC_TEST: water as bladder distending media|DIAGNOSTIC_TEST: intravenous dye|DIAGNOSTIC_TEST: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stent vs. Angioplasty for Treatment of Thrombosed AV Grafts: Long-Term Outcomes
Status: UNKNOWN
Conditions: Hyperplasia|Stenosis
Interventions: PROCEDURE: angioplasty|PROCEDURE: stent placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment on Work Experience in Patients With Stage I-III Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer
Interventions: OTHER: Interview|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative|Healing Surgical Wounds
Interventions: DRUG: Cyanoacrylate|PROCEDURE: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Recovery Enhancement and Sleep Training
Status: COMPLETED
Conditions: Sleep|Performance|Mental Health|Stress|Anxiety
Interventions: BEHAVIORAL: Sleep Diary|DEVICE: Fitness tracker|DEVICE: Blue-Blocking Glasses|DEVICE: LED light|OTHER: Information Session|BEHAVIORAL: Text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antiviral Efficacy, Pharmacokinetics and Safety of BILN 2061 ZW in Patients With Cirrhosis and Chronic Hepatitis C
Status: COMPLETED
Conditions: Liver Cirrhosis|Hepatitis C, Chronic
Interventions: DRUG: BILN 2061 ZW|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Long-term Effects Secondary to Cancer Therapy in Children|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: cognitive assessment|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Clinical Outcomes of the One-step Cartilage Transplantation in Cartilage Defects of the Knee With Conservative Treatment
Status: RECRUITING
Conditions: Cartilage Damage
Interventions: DRUG: Instant MSC Product accompanying Autologous Chondron Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Relationship Between Oxidative Stress and Human Reproduction
Status: RECRUITING
Conditions: IVF|Pregnancy|Oxidative Stress|Fertility Disorders
Interventions: DIAGNOSTIC_TEST: Measurement of oxidative stress levels (Malondialdehide, glutathione disulphate, total antioxidant capacity, superoxide dismutase and carbonylated proteins )
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacodynamic Open-Label Trial With VXA-A1.1 Oral H1 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Seasonal Influenza Preventative Vaccine Pharmacodynamics
Interventions: BIOLOGICAL: VXA-A1.1 H1 Tablet Vaccine (small)|BIOLOGICAL: VXA-A1.1 H1 Tablet Vaccine (large)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Mechanisms of Transcranial Direct Current Stimulation (tDCS) - Effects on Working Memory in Schizophrenia
Status: UNKNOWN
Conditions: Anodal Stimulation tDCS|Schizophrenia|Working Memory
Interventions: PROCEDURE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees
Status: RECRUITING
Conditions: Amputation|Amputation; Traumatic, Leg, Lower|Limb; Absence, Congenital, Lower|Prosthesis User|Lower Limb Amputation Above Knee (Injury)|Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions: DEVICE: Power Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing PharmacoTherapy In the Multimorbid Elderly in Primary CAre: the OPTICA Trial
Status: COMPLETED
Conditions: Multimorbidity|Polypharmacy
Interventions: DEVICE: STRIPA intervention|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: BuMA Supreme|DEVICE: BuMA™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Belimumab in Early Lupus
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic|Lupus Erythematosus
Interventions: BIOLOGICAL: Belimumab|BIOLOGICAL: Belimumab/Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
Status: COMPLETED
Conditions: Cytomegalovirus (CMV)
Interventions: DRUG: Maribavir|DRUG: Ganciclovir|DRUG: Valganciclovir|DRUG: Foscarnet|DRUG: Cidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Statewide Intervention to Reduce Use of Unproven or Ineffective Breast Cancer Care
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Basic public reporting|BEHAVIORAL: Enhanced intervention|BEHAVIORAL: Control group - observational
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Bioequivalence of Single Oral Dose of Esomeprazole Capsule and Tablet Formulation in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Esomeprazole Capsule|DRUG: Esomeprazole Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Zeller Entspannung Film Coated Tablets on Acute Stress
Status: COMPLETED
Conditions: The Primary Condition Studied for This Trial is Acute Stress
Interventions: DRUG: Zeller Entspannung film coated tablet|DRUG: Placebo|OTHER: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Lens A (fanfilcon A)|DEVICE: Lens B (lotrafilcon B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer
Status: SUSPENDED
Conditions: Extensive Stage Lung Small Cell Carcinoma|Limited Stage Lung Small Cell Carcinoma|Platinum-Resistant Lung Small Cell Carcinoma|Platinum-Sensitive Lung Small Cell Carcinoma|Recurrent Lung Small Cell Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Pembrolizumab|DRUG: Tazemetostat Hydrobromide|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Merestinib and LY2874455 for Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Relapsed Adult Acute Myeloid Leukemia|Refractory Adult Acute Myeloid Leukemia
Interventions: DRUG: Merestinib|DRUG: LY2874455
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Negative Mental Images and Memories in Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Imaginal Rescripting|BEHAVIORAL: Imaginal Exposure|OTHER: Supportive Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostrate Cancer|Renal Cell Carcinoma|Metastatic Melanoma|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: BMS-936558 (MDX-1106)|BIOLOGICAL: BMS-936558 (MDX-1106)|BIOLOGICAL: BMS-936558 (MDX-1106)|BIOLOGICAL: BMS-936558 (MDX-1106)|BIOLOGICAL: BMS-936558 (MDX-1106)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptation of Conventional Versus Virtually Fabricated Ear Prosthesis in Patients With Auricular Defects
Status: COMPLETED
Conditions: Ear Deformity External
Interventions: OTHER: virtually fabricated ear prosthesis|OTHER: conventionally fabricated ear prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adapting and Testing a Novel Self-Compassion Intervention to Reduce Lung Cancer Stigma
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Mindful Self-Compassion for Lung Cancer (MSC-LC)|OTHER: Enhanced standard of care with waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptance-based Self-help for Individuals With Visible Difference and Social Anxiety
Status: COMPLETED
Conditions: Visible Difference|Acceptance and Commitment Therapy|ACT|Skin Condition|Hair Condition|Craniofacial|Burns
Interventions: BEHAVIORAL: Acceptance-based self-help intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oxytocin Nasal Spray on Social Affiliation
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Development of MRI Protocols and Associated Explorations (EEG, NIRS) in Healthy Volunteers
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: RADIATION: MRI|DEVICE: EEG|DEVICE: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Oxytocin on Hemodynamics in Patients Undergoing Laparoscopic Myomectomy
Status: UNKNOWN
Conditions: Oxytocin|Hemodynamic Monitoring|Laparoscopic Surgery
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
Status: NOT_YET_RECRUITING
Conditions: Intubation Complication|Stroke, Ischemic|Stroke Hemorrhagic|Head Trauma|Cardiac Arrest|Ventilator Associated Pneumonia|Airway Clearance Impairment
Interventions: DEVICE: airway clearance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection
Status: UNKNOWN
Conditions: Covid19|Pneumonia|Coagulation Disorder|Pulmonary Embolism
Interventions: DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sensory Diets on Children's Sensory Processing Skills, Psychosocial Skills, and Classroom Engagement
Status: COMPLETED
Conditions: Sensory Processing Disorder|Special Education|Autism
Interventions: OTHER: Sensory diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplant for Fanconi Anemia
Status: COMPLETED
Conditions: Fanconi Anemia
Interventions: DEVICE: CliniMACs device|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goals in Focus: CBT for Motivational Negative Symptoms of Psychosis
Status: RECRUITING
Conditions: Psychosis|Schizophrenia|Negative Symptoms With Primary Psychotic Disorder
Interventions: BEHAVIORAL: Goals in Focus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLS-5310 Vaccine in Healthy Volunteers for the Prevention of SARS-CoV-2 (COVID-19)
Status: UNKNOWN
Conditions: Covid19|Healthy
Interventions: BIOLOGICAL: GLS-5130|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Emotion-Diet Interactions in Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related|Stress, Psychological|Glucose Intolerance During Pregnancy|Emotional Stress|Postprandial Hyperglycemia|Insulin Sensitivity/Resistance
Interventions: BEHAVIORAL: Psychosocial stress|BEHAVIORAL: Control non-stress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perturbation Based Training And Bobath-Based Trunk Exercises On Gait , Postural Control And Mobility
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Rocker board training|OTHER: Stable surface training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Apixaban 5 mg Film-coated Tablets in Healthy Thai Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Apixaban 5MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Best Care for Abdominal Emergencies Study
Status: UNKNOWN
Conditions: Acute Abdomen|Bowel Obstruction|Bowel; Ischemic, Acute|Bowel Perforated|Peritonitis
Interventions: PROCEDURE: Laparotomy or laparoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness as Treatment of Sexological Problems
Status: COMPLETED
Conditions: Sexual Dysfunction|Sexual Dysfunctions, Psychological|Sexual Dysfunctions, Physiological
Interventions: BEHAVIORAL: Mindfulness in Sex Therapy and Intimate Relationships (MSIR)|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of 16055 NFL Delta Gly4 Env Protein Trimer and Trimer 4571 Combined With 3M-052-AF + Alum Adjuvant and Ad4-Env145NFL Viral Particles as Heterologous Prime-boost Regimens in Adult Participants Without HIV.
Status: RECRUITING
Conditions: HIV
Interventions: BIOLOGICAL: 16055 NFL delta Gly4 trimer|BIOLOGICAL: Trimer 4571|BIOLOGICAL: Ad4-Env145NFL, 5 x 108 viral particles (vp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Glutamine and Mucositis of Head and Neck Cancer Patients Undergoing Radiation
Status: UNKNOWN
Conditions: Head and Neck Cancer|Mucositis
Interventions: DIETARY_SUPPLEMENT: Glutamine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BEB Conditioning Regimen for Autologous Stem-cell Transplantation(ASCT) in Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Busulfan|DRUG: Etoposide|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Brain Metastases
Interventions: DRUG: Eribulin Mesylate|DEVICE: MRI|DRUG: Pre-Medication: Zofran|DRUG: Pre-Medication: Decadron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Correlation Between Changes of Shear Wave Elastography and Surface Electromyogram of the Masseter
Status: COMPLETED
Conditions: Masseter Muscle Spasm
Interventions: DEVICE: Ultrasound exam by Supersonic Shear Imaging® technique|DEVICE: EMG examination by electromyograph Keypoint system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study Comparing Tension-free Vaginal Tape With the Monarc Procedure for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Tension-free Vaginal Tape|DEVICE: Monarc sub-fascial hammock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Response Rate of Neo-adjuvant Paclitaxel (Taxol) in Nigerian Women With Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DRUG: Paclitaxel|DRUG: Perjeta|DRUG: Herceptin SC|DRUG: Tamoxifen|DRUG: Letrozole|DRUG: LHRH agonist|DRUG: FEC|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of an Evidence Based Post-Traumatic Stress Disorder (PTSD) Treatment in Public Sector Settings
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: STAIR/NT treatment|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension|Sleep Disordered Breathing
Interventions: DRUG: Riociguat|PROCEDURE: Pulmonary Endarteriectomy|PROCEDURE: Ballon Pulmonary Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colposcopy Findings Among Women With High Risk HPV Other Than HPV 16/18 and Normal Cytology
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: OTHER: Colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Amplification of Positivity to Enhance Social Connections in Anxiety and Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: Amplification of Positivity Training (6 Sessions)|BEHAVIORAL: Stress Management Training (6 Sessions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on Comparison of EDOF Lenses (Switzerland)
Status: COMPLETED
Conditions: Cataract|Lens Opacities
Interventions: DEVICE: IOL implantation experimental (ISOPURE 1.2.3.)|DEVICE: IOL implantation active comparator (Acrysof Vivity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Neck Pain in Adults
Status: COMPLETED
Conditions: Neck Pain
Interventions: DEVICE: BEMER|PROCEDURE: OMT|PROCEDURE: Sham OMT + Sham BEMER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone in Alcohol Use Disorder (SAUD)
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: OTHER: Placebo|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Compulsive Exercise Group Therapy for Eating Disorders
Status: UNKNOWN
Conditions: Eating Disorders in Adolescence
Interventions: BEHAVIORAL: Newbridge Eating disorders Activity Treatment group|BEHAVIORAL: Newbridge House treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capmatinib in Patients With Non-small Cell Lung Cancer Harboring cMET exon14 Skipping Mutation
Status: UNKNOWN
Conditions: Cancer|Lung Cancer Metastatic|MET Gene Mutation
Interventions: DRUG: Capmatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria
Status: COMPLETED
Conditions: Hyperuricemia|Albuminuria|Type 2 Diabetes
Interventions: DRUG: Verinurad 9 mg+Febuxostat 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Nurse-coordinated Integrated Care Model for Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Nurse-coordinated integrated care model for AF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy and Safety of Burfiralimab (hzVSF-v13) and DMRD (Disease-modifying Antirheumatic Drug)
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Rheumatoid Arthritis
Interventions: DRUG: Burfiralimab|DRUG: SOC (Standard of care)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Ferumoxytol With Placebo for the Treatment of Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-education in Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial
Status: ENROLLING_BY_INVITATION
Conditions: Rotator Cuff Tears|Pain, Shoulder|Surgery
Interventions: OTHER: Cross-education training|OTHER: Standard exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Connect: Patients and Providers Use of a Secure Website for Blood Glucose Monitoring in Type-2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Subject/Provider Portal "Diabetes Connected Health" tool - Deluxe|OTHER: Subject only Portal "Diabetes Connected Health Tool" Basic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Trial to Assess the Potency of SOR007 Ointment in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: SOR007 Ointment 2.0%|DRUG: SOR007 Ointment 1.0%|DRUG: SOR007 Ointment 0.3%|DRUG: SOR007 Ointment 0.15%|DRUG: SOR007 Ointment Placebo|DRUG: Taclonex® Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hydrocortisone|DRUG: Glucose 33%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sativex Thorough QT/QTc Study
Status: COMPLETED
Conditions: Effects of Sativex on ECG
Interventions: DRUG: Placebo spray and oral moxifloxacin placebo|DRUG: Sativex spray and oral moxifloxacin placebo|DRUG: Sativex spray and oral moxifloxacin placebo|DRUG: Placebo spray and moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fractional CO2 Laser Versus Pulsed Dye Laser in Nail Psoriasis
Status: UNKNOWN
Conditions: the Efficacy of Fractional Co2 Laser in Nail Psoriais
Interventions: DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT