pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Selective D-Dimer Testing Compared With Uniform D-Dimer Testing in the Diagnosis of Deep Vein Thrombosis (SELECT)
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: PROCEDURE: D-dimer testing|PROCEDURE: D-dimer testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Surgery Versus Radiotherapy for Locally Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: Prostatectomy/Surgery|OTHER: Radiotherapy with adjuvant androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normative Data Collection Study of the Zilia Ocular for the Measurement of Oxygen Saturation in the Retina
Status: TERMINATED
Conditions: Retinal Vascular|Retina
Interventions: DEVICE: Zilia Ocular
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of Zanubrutinib in Participants With Primary Membranous Nephropathy
Status: RECRUITING
Conditions: Primary Membranous Nephropathy
Interventions: DRUG: Zanubrutinib|DRUG: Tacrolimus|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LC23-1306 in Healthy Male Subjects
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: LC23-1306|DRUG: placebo|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT (Randomized Control Trial) of TD139 vs Placebo in HV's (Human Volunteers) and IPF Patients
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Inhaled TD139|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Combination Therapy With PD-1 Antibody and Peg-IFNα in CHB Patients
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Sintilimab|DRUG: NAs|DRUG: Peg-IFNα-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viral Therapy in Treating Patients With Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer That Did Not Respond to Platinum Chemotherapy
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Wild-type Reovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms
Status: RECRUITING
Conditions: Rotator Cuff Tendinosis|Rotator Cuff Tendinitis|Rotator Cuff Injuries|Subacromial Pain Syndrome
Interventions: OTHER: Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of NMP and TDCS vs Pharmacological Treatment in Cancer Patients With Lower Limb Pain
Status: NOT_YET_RECRUITING
Conditions: Pain Cancer
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DEVICE: Ultrasound-guided percutaneous neuromodulation (NMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Taste and Acceptability of a High Protein Ice Cream Compared With Hospital Milkshake Nutritional Supplement
Status: COMPLETED
Conditions: Femoral Fragility Fractures|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Standard milkshake ONS (Fortisip Compact Protein)|DIETARY_SUPPLEMENT: High protein, fortified, ice cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Adjuvant Radiotherapy in Small Oropharyngeal Squamous Cell Cancer and Single Lymph Node Metastasis.
Status: COMPLETED
Conditions: Oropharyngeal Cancer|Oral Cancer|Lymph Node Metastasis
Interventions: RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penile Implant Intraoperative Measurements Planning Chart
Status: UNKNOWN
Conditions: Erectile Dysfunction|Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction With Diabetes Mellitus|Erectile Dysfunction Due to Arterial Disease|Erectile Dysfunction Due to Injury|Erectile Dysfunction Due to Neuropathy|Erectile Dysfunction Following Simple Prostatectomy|Erectile Dysfunction Due to Venous Disorder|Erectile Dysfunction With Type 1 Diabetes Mellitus|Erection; Incomplete|Erectile Dysfunction Due to Endocrine Disease
Interventions: DIAGNOSTIC_TEST: Penile Prosthesis Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in Humans
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Butter oil|DIETARY_SUPPLEMENT: Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implementing Psychosocial Interventions to Syrian Refugee Women Who Are Exposed to Psychological Trauma
Status: COMPLETED
Conditions: Psychological Distress|Psychological Trauma
Interventions: BEHAVIORAL: Culturally Adapted Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue Flossing in Tennis Elbow Patients
Status: UNKNOWN
Conditions: Tennis Elbow
Interventions: OTHER: Tissue flossing|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy|OTHER: Waiting List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of STSA-1201 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: STSA-1201 Subcutaneous injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staccato Loxapine in Agitation (Proof of Concept)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Inhaled Placebo|DRUG: Inhaled Loxapine 5 mg|DRUG: Inhaled Loxapine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3209590 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3209590|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Protective Efficacy of FF-3 Dry Powder in Healthy Subjects Infected With Influenza Challenge Strain
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: FF-3 dry powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain
Status: TERMINATED
Conditions: Lumbar Radiculopathy
Interventions: DRUG: SX600|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Cranial Irradiation in Patients With HER-2-Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Prophylactic Cranial Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correct Use of Sequential Formoterol and Budesonide Inhaler Capsule Treatment Via Aerolizer and Patient Satisfaction in Asthmatics
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Foradil Combi (Formoterol-budesonide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survival of the Probiotic Lacticaseibacillus Paracasei Strain Shirota (LcS) in the GI Tract of Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Drink one bottle of Yakult a day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System
Status: COMPLETED
Conditions: ARDS (Acute Respiratory Distress Syndrome)|Respiratory Acidosis
Interventions: DEVICE: Abylcap® System: blood flow (QB): 200mL/min; gas flow (QG):7L/min|DEVICE: Abylcap® System: blood flow (QB): 300mL/min; gas flow (QG):7L/min|DEVICE: Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):7L/min|DEVICE: Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):1.5L/min|DEVICE: Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):3L/min|DEVICE: Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):6L/min|DEVICE: Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):8L/min
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of USL261 in Patients With Increased Bouts of Seizure Activity in the EMU
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: USL261|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Punchgrafting Techniques for Vitiligo
Status: UNKNOWN
Conditions: Non-segmental Vitiligo|Segmental Vitiligo|Piebaldism
Interventions: PROCEDURE: punchgrafting|PROCEDURE: punchgrafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
Status: COMPLETED
Conditions: Type1diabetes|Type1 Diabetes Mellitus|Diabetic Kidney Disease|Juvenile Diabetes|Diabetic Nephropathies|Diabetes Complications|Diabetes, Autoimmune
Interventions: DRUG: Starbucks® Cold brew - 325ml bottle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infracalcaneal Peppering Injection Technique for Chronic Plantar Fasciitis
Status: RECRUITING
Conditions: Chronic Plantar Fasciitis
Interventions: DRUG: Corticosteroid injection (CSI) with local anesthetic (LA)|DRUG: Local anesthetic (LA) with Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique
Status: COMPLETED
Conditions: Colonoscopy|Digestive System|Endoscopy|Gastrointestinal Disease
Interventions: PROCEDURE: water immersion colonoscopy|PROCEDURE: standard air colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: BioGlue as an Adjunct for Structural Repair and Hemostasis in Chinese Acute Type A Aortic Dissections Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Type A Aortic Dissection
Interventions: DEVICE: BioGlue Surgical Adhesive|OTHER: Traditional Surgical Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xylitol - Healthcare Associated Infection Reduction in Stem Cell Transplant Patients
Status: TERMINATED
Conditions: Allogeneic Hematopoietic Cell Transplantation
Interventions: DRUG: Xylitol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry
Status: NOT_YET_RECRUITING
Conditions: Vasovagal Syncope|AV Block-2Nd Degree-Type 1|Sinus Pause
Interventions: PROCEDURE: Ablation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DIAGNOSTIC_TEST: Saliva obtaining
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine (VITHA-A)
Status: COMPLETED
Conditions: Hepatitis A Vaccine
Interventions: BIOLOGICAL: inactivated hepatitis A vaccine|BIOLOGICAL: Havrix Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Tapentadol in Post-Bunionectomy Pain
Status: COMPLETED
Conditions: Bunion|Pain
Interventions: DRUG: Tapentadol|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DRUG: T-DM1|DRUG: Capecitabine|RADIATION: External Beam Radiation Therapy 0|RADIATION: External Beam Radiation Therapy 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: RVT-501 0.5% ointment|DRUG: Vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: URLC10, VEGFR1 and VEGFR2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Sex Therapy on Patients With Takotsubo Cardiomyopathy
Status: UNKNOWN
Conditions: Takotsubo Cardiomyopathy|Sexual Dysfunction
Interventions: BEHAVIORAL: Mindfulness-Based Sex Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Potentiating Effect of tDCS on Opioid Analgesia of Pain Threshold in Humans
Status: UNKNOWN
Conditions: Acute Pain
Interventions: DRUG: Remifentanil|DEVICE: Active tDCS|DEVICE: Sham tDCS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Onset of Term and Preterm Labour
Status: UNKNOWN
Conditions: Preterm Pregnancy|Preterm Birth|Preterm Birth Complication|Preterm Premature Rupture of Membrane|Preterm Labor
Interventions: OTHER: Samples required from group 1 (procedure within observational study)|OTHER: Samples required from group 2 (procedure within observational study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Triple-dose Tuberculosis Retreatment Regimen
Status: ACTIVE_NOT_RECRUITING
Conditions: Multidrug-resistant Tuberculosis|Pulmonary Tuberculosis|Tuberculosis|Resistance to Tuberculostatic Drugs
Interventions: DRUG: 6EH³R³Z|DRUG: 6EHRZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity and the Safety of an Adjuvanted Influenza Vaccine Candidate
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK1247446A Group|BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pain Evaluation and Treatment in Clinical Settings
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Functional Limitations|Musculoskeletal Disorders
Interventions: DEVICE: tDCS associated to functional activities|OTHER: Conservative physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Protocol to Efficiently Induce Itch
Status: ENROLLING_BY_INVITATION
Conditions: Itch
Interventions: DRUG: Anti-histamine cream 1 hour|DRUG: Local anesthetic cream 1 hour
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of V940 Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)
Status: RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: V940|BIOLOGICAL: Pembrolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate Physical Activity on Glycemic Control in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Brisk Walk|OTHER: Strength training|OTHER: Aerobic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma
Status: RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Neoplasm in the Central Nervous System|Metastatic Melanoma
Interventions: DRUG: Dabrafenib|DRUG: MEK-1/MEKK-1 Inhibitor E6201|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Resistance Training on Metabolic Control and Outcome in Prediabetes (NMR-based Metabonomics)
Status: UNKNOWN
Conditions: Prediabetic State
Interventions: BEHAVIORAL: resistance training|BEHAVIORAL: aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fast Track Diagnosis of Skin Cancer by Advanced Imaging
Status: COMPLETED
Conditions: Malignant Melanoma|Nevus, Pigmented|Basal Cell Carcinoma|Seborrheic Keratosis
Interventions: DIAGNOSTIC_TEST: optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Multicenter Study of High Dose Chemotherapy With Autologous Stem Cell Transplant Followed by Maintenance Therapy With Romidepsin for the Treatment of T Cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: T Cell Non-Hodgkin Lymphoma
Interventions: OTHER: High Dose Chemotherapy with Autologous Stem Cell Transplant Followed by Maintenance Therapy with Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: myDC/pDC in Stage III Melanoma Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: A: myDC vaccination|DRUG: B: pDC vaccination|DRUG: C: combined myDC/pDC vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Mal de Debarquement Syndrome
Status: COMPLETED
Conditions: Mal de Debarquement Syndrome
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab + Endocrine Treatment vs Endocrine Treatment as First Line in Postmenopausal Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Bevacizumab|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anastrozole Biphosphonate Study in Postmenopausal Women With Hormone-Receptor-Positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Risedronate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Elastic Taping on the Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprains|Chronic Ankle Instability|Athletes Foot
Interventions: OTHER: Tape with tension|OTHER: Tape without tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Guadecitabine|DRUG: Mocetinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Fusion
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Inter-semispinalis Plane Block|DRUG: Opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Devices Using Near-infra Red Spectroscopy During a Vascular Occlusion Test
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: vascular occlusion test|DEVICE: vascular occlusion test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer|Alzheimer Disease|Age-related Macular Degeneration|Parkinson Disease|Cardiac Disease|Ischemic Stroke|Hemorrhagic Stroke
Interventions: BEHAVIORAL: Support provided by social worker|OTHER: Information booklet receipt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
Status: COMPLETED
Conditions: Depression, Anxiety|Self-Injurious Behavior
Interventions: BEHAVIORAL: Mindfulness plus mood monitoring|BEHAVIORAL: Mood monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exopulse Mollii Suit and Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia, Primary
Interventions: DEVICE: Exoplulse Mollii suit|DEVICE: Exopulse Mollii suit (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor, Adult|Advanced Solid Tumor|Advanced Cancer|Metastatic Cancer|Refractory Cancer
Interventions: DRUG: MPT-0118|DRUG: MPT-0118 + pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Status: COMPLETED
Conditions: Healthy|Overweight
Interventions: DIETARY_SUPPLEMENT: 40 g Gum acacia (FibregumTM)|DIETARY_SUPPLEMENT: 20 g Gum acacia (FibregumTM)|DIETARY_SUPPLEMENT: 0 g Gum acacia (FibregumTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy Between Restricted Kinematic Alignment vs Mechanical Alignment in Bilateral TKA
Status: RECRUITING
Conditions: Osteoarthritis, Knee|TKA
Interventions: PROCEDURE: Restricted kinematic alignment|PROCEDURE: Mechanical alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Replacement Therapy Clinical Trial for Participants With Spinal Muscular Atrophy Type 1
Status: COMPLETED
Conditions: SMA - Spinal Muscular Atrophy|Gene Therapy
Interventions: BIOLOGICAL: Onasemnogene Abeparvovec-xioi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Dexmedetomidine Versus Neostigmine/Atropine in Postdural Puncture Headache
Status: COMPLETED
Conditions: Postdural Puncture Headache
Interventions: DRUG: Dexmedetomidine|DRUG: Neostigmine/atropine|OTHER: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics and Pharmacodynamics of Hemp-based Topical Cannabinoid Products
Status: COMPLETED
Conditions: Cannabis|Drug Effect
Interventions: DRUG: CBD|DRUG: THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TR-701 FA 200 mg|DRUG: TR-701 FA 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Integrated Community-based Intervention Package in Improving Maternal and Neonatal Health Outcomes
Status: RECRUITING
Conditions: Integrated Community-based Intervention Package|Breastfeeding, Exclusive|Morbidity;Newborn|Complementary Feeding|Knowledge, Attitudes, Practice|Food Security|Birth Preparedness and Complication Readiness Plan|Neonatal Care|Health Care Seeking Behavior|Delivery Care|Postnatal Care
Interventions: BEHAVIORAL: Behaviour Change Communication and Male involvement intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Omnitram|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Syndesmotic Screw in Neutral Position Versus Maximum Ankle Dorsiflexion in Ankle Fractures; Comparative Study.
Status: RECRUITING
Conditions: Syndesmotic Injuries
Interventions: PROCEDURE: syndesmosis fixation with screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of SB-751689 or rhPTH(1-34) on Excretion of Calcium and Phosphate in Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: rhPTH(1-34)|DRUG: SB-751689 100 mg|DRUG: SB-751689 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Status: COMPLETED
Conditions: Exercise|Gait|Cognitive Decline|Caregiver Burden|Cognitive Impairment|Dementia|Alzheimer Disease|Mild Cognitive Impairment|Respite Care|Mental Health|Depression|Music Therapy|Psychosocial Intervention|Cognition|Geriatric Assessment|Cognitive Dysfunction|Cognitive Aging|Outcome Assessment, Health Care|Balance|Fall|Walking|Affect|Physical Exertion|Memory Deficit|Memory Disorders|Memory Impairment|Neuropsychological Tests|Executive Function|Middle Aged|Healthy Aging|Elderly
Interventions: BEHAVIORAL: Group exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: RADIATION: External radiotherapy + curietherapy|DRUG: Vistide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)
Status: UNKNOWN
Conditions: Osteoarthritis, Hip
Interventions: DEVICE: KINCISE|DEVICE: Traditional Handheld Mallet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SOURT OUT IV TRIAL
Status: COMPLETED
Conditions: Ischemic Heart Disease|Coronary Atherosclerosis|Percutaneous Coronary Intervention
Interventions: DEVICE: Percutaneous coronary intervention (Xience V stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initiation of Airway Code: The Role of the Airway Team in Unexpected Difficult Airways
Status: RECRUITING
Conditions: Unexpected Difficult Airway|Intubation;Difficult|Airway Management
Interventions: PROCEDURE: Videolaryngoscopy|PROCEDURE: FOB|PROCEDURE: FOB+Aintree|PROCEDURE: Classic intubation with laryngoscopy|PROCEDURE: Others
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Acute Tart Cherry Supplement Formulation and Dose on Inflammation and Oxidative Capacity
Status: COMPLETED
Conditions: Inflammation|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: tart cherry|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Various Supraglottic Airway Devices for Fiberoptical Guided Tracheal Intubation
Status: UNKNOWN
Conditions: Intubation; Difficult
Interventions: DEVICE: SAD 1|DEVICE: SAD 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Aortic Stenosis
Interventions: DRUG: Acetylsalicylic acid|DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cycle to Fun - 'Exergames' for Inpatient Rehabilitation for Children/Youth With CP
Status: COMPLETED
Conditions: Cerebral Palsy|Orthopedic Surgery
Interventions: DEVICE: Exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla
Status: UNKNOWN
Conditions: Common Bile Duct Gallstones|Choledocholithiasis
Interventions: PROCEDURE: Spyglass|PROCEDURE: Balloon dilation of the papilla|PROCEDURE: EHL (electrohydraulic lithotripsy)|PROCEDURE: ERCP (Endoscopic retrograde cholangiopancreatography)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Simple Renal Cysts on Renal Function
Status: UNKNOWN
Conditions: Simple Renal Cyst|Renal Function Disorder
Interventions: PROCEDURE: CT scan with contrast|RADIATION: Nephroscintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Prompting the Supply of Zinc/LO-ORS Co-packs in the Private Sector Plus BCI on Childhood Diarrhea Treatment
Status: COMPLETED
Conditions: Diarrhea, Infantile
Interventions: OTHER: Private sector component + modified BCC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
Status: NOT_YET_RECRUITING
Conditions: Post-operative Pain, Acute|Opioid Use, Unspecified|Arthroplasty Complications|Knee Osteoarthritis|Shoulder Arthritis|Hip Arthritis
Interventions: DEVICE: Pain Coach App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Depression|Anxiety|Psychological Distress|Social Phobia|Post Traumatic Stress Disorder|Suicidal Ideation|Sex, Unsafe|Discrimination, Social|Behavior, Risk|Self Esteem
Interventions: BEHAVIORAL: Expressive writing|BEHAVIORAL: Self-affirmation|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of VascuActive Device on Foot Perfusion, Hemodynamics and Exercise Capacity in Patients With PVD & Limb Ischemia
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: VascuActive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Cold Blood vs Crystalloid Cardioplegia in Aortic Valve Surgery
Status: COMPLETED
Conditions: Aortic Valve Disease|Coronary Artery Disease
Interventions: PROCEDURE: Myocardial protection techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIR-1111: A Prototype Human CMV-based Vaccine for Human Immunodeficiency Virus (HIV) in Healthy Volunteers
Status: COMPLETED
Conditions: HIV I Infection
Interventions: BIOLOGICAL: VIR-1111|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hypotension Prediction Index (HPI) SMART-BP Trial
Status: TERMINATED
Conditions: Moderate to High-risk Noncardiac Surgery
Interventions: DEVICE: AcumenTM HPI Software Feature|OTHER: Non-protocolized Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Adherence and Outcomes in Three Modalities of Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP (REMstar (Respironics))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VIA Disc Nucleus Pulposus Older Patients Pilot
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease|Low Back Pain|Disc Degeneration
Interventions: OTHER: VIA Disc Nucleus Pulposus Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease Inhibitor
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Lopinavir and ritonavir|DRUG: Triple therapy with ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Quetiapine Fumarate (SEROQUEL) Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Markers of Appetite Regulation During Exogenous Ketosis
Status: UNKNOWN
Conditions: Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Tap water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correction of Multiplanar Deformities Around the Knee With Monolateral External Fixator
Status: UNKNOWN
Conditions: Deformities Around the Knee in Pedietrics
Interventions: PROCEDURE: correction of deformities around the knee with external fixator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Levator Ani Release and Post Isometric Relaxation Among Patients With Coccydynia
Status: RECRUITING
Conditions: Coccydynia
Interventions: OTHER: Levator ani release|OTHER: Post isometric relaxion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Combination of Temsirolimus and Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma
Status: RECRUITING
Conditions: Normal Tension Glaucoma
Interventions: PROCEDURE: Trabeculectomy|PROCEDURE: Deep Sclerectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colon Cancer|Metastatic Rectum Cancer
Interventions: DRUG: Topical Tretinoin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impacted Canine and Mixed-reality Technology - RCT
Status: RECRUITING
Conditions: Tooth, Impacted
Interventions: PROCEDURE: Planning of alignment with HoloLens 2|PROCEDURE: No planning of alignment with HoloLens 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-course of Mitochondrial Biogenic Gene and Protein Expression in Exercised Human Skeletal Muscle
Status: UNKNOWN
Conditions: Mitochondrial Biogenesis
Interventions: OTHER: LO|OTHER: HI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Chlorhexidine - Isopropyl alcohol|DRUG: Povidone-Iodine Scrub and Paint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)
Status: COMPLETED
Conditions: Malignant Peripheral Nerve Sheath Tumors (MPNST)|Sarcoma
Interventions: DRUG: ganetespib|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Free DNA in Cardiac Sarcoidosis
Status: RECRUITING
Conditions: Sarcoidosis With Myocarditis|Sarcoidosis|Healthy|ST Elevation Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: cell free DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gabapentin for Alcohol Relapse Prevention
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcohol Withdrawal
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: 3.2 mg intranasal carbetocin|DRUG: 9.6 mg intranasal carbetocin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder|Severe Depression
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Placebo-controlled, Randomized, Parallel-group Study to Evaluate the Activity of Oral AB1010 in Adults Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Masitinib|DRUG: Masitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Propofol Infusion for Refractory Chronic Primary Insomnia
Status: COMPLETED
Conditions: Insomnia|Sleep Disorder|Dyssomnia
Interventions: DRUG: propofol injectable emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Aerobic Exercise and Resistant Hypertension
Status: RECRUITING
Conditions: Resistant Hypertension
Interventions: OTHER: Moderate-intensity interval training (MIIT)|OTHER: Moderate-intensity continuous training (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan, hydrochlorothiazide and amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS and Physical Therapy in Chronic Migraine
Status: RECRUITING
Conditions: Migraine Disorders
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|OTHER: real Physical Therapy|OTHER: placebo Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT