pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support
Status: RECRUITING
Conditions: Drug Effect
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl|DRUG: Midazolam|DRUG: Morphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Pediatrics With Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (pALL) or Lymphoblastic Lymphoma
Status: TERMINATED
Conditions: B-Cell Pediatric ALL
Interventions: DRUG: Moxetumomab Pasudotox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC
Status: RECRUITING
Conditions: Immune-Mediated Hepatitis|Liver Failure|Hepatocellular Carcinoma
Interventions: OTHER: DPMAS+LPE|OTHER: PE|OTHER: Comprehensive internal medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of Anti-bodies Against Clostridium Difficile Toxins and Prevalence of Asymptomatic Carriage of Clostridium Difficile in IBD Patients.
Status: UNKNOWN
Conditions: Clostridium Difficile|Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Determination of serum anti-toxin Abs for C. difficile
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Anesthetic Gel Patches to Reduce Pain of Palatal Injection
Status: COMPLETED
Conditions: Anesthesia, Dental
Interventions: DRUG: Topicale GelPatch (Benzocaine 18%)|DRUG: Benzocaine oral gel 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cutting-Balloon Angioplasty With Everolimus-Eluting Stent(EES) in the Treatment of Coronary Calcified Lesion(CCL) Guided by Intravascular Ultrasonography(IVUS)
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Wolverine cutting balloon|DEVICE: Non-compliant balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Working Memory Training on Delay Discounting Among Cigarette Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder/Cigarette Smoking
Interventions: BEHAVIORAL: Working Memory Training (Active Intervention) + Behavioral Intervention|BEHAVIORAL: Control Training (CT) + Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Norepinephrine for Orthostatic Hypotension
Status: COMPLETED
Conditions: Orthostatic Hypertension
Interventions: DRUG: Intravenous Norepinephrine Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gan & Lee Insulin Glargine Target Type (2) Evaluating Research
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: Gan & Lee Insulin Glargine Injection|BIOLOGICAL: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Graft Vs Host Disease|Graft-versus-host-disease|Graft Versus Host Disease
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GaStroEsophageal effeCt of indobUfen Versus aspiRin in Patients Undergoing Dual antiplatElet Therapy
Status: UNKNOWN
Conditions: Coronary Artery Disease|Gastroesophageal Reflux Disease
Interventions: DRUG: Indobufen and aspirin mimetic|DRUG: Aspirin and indobufen mimetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Macrolane VRF30 for Volume Restoration and Contouring of the Buttocks
Status: COMPLETED
Conditions: Volume Restoration and Shaping of the Buttocks
Interventions: DEVICE: Macrolane VRF30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anticholinergic Deprescription in Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Anticholinergic Deprescription|DRUG: No Anticholinergic Deprescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
Status: UNKNOWN
Conditions: Portal Hypertension|Chronic Liver Disease|Cirrhosis
Interventions: PROCEDURE: Transjugular hepatic venous pressure gradient measurement with liver biopsy|PROCEDURE: Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Lesions
Status: RECRUITING
Conditions: Patient With Radiotherapy (Linac MRI)|Mobile Cancerous Lesion
Interventions: COMBINATION_PRODUCT: With non-magnetic screen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase III PI-88 in the Adjuvant Treatment of Subjects With Hepatitis Virus Related HCC After Surgical Resection
Status: TERMINATED
Conditions: Cancer|Liver Cancer|Hepatocellular Carcinoma
Interventions: DRUG: PI-88|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Targeting CD19 and CD22 Chimeric Antigen Receptor T Lymphocytes in the Treatment of Recurrent or Refractory B Cell Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Relapsed and Refractory|Lymphoid Hematological Malignancies
Interventions: DRUG: GC022F CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Myeloablative Conditioning and Bone Marrow Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Hemoglobinopathies
Interventions: DRUG: Thymoglobulin|DRUG: Fludarabine|DRUG: Cyclophosphamide (CTX)|DRUG: Mesna|DRUG: Sirolimus|DRUG: Mycophenolate mofetil (MMF)|PROCEDURE: Bone marrow transplantation|RADIATION: Total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simulation-based Procedure Training for Novice Cardiac Device Implanters Towards Implant Proficiency
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice
Interventions: OTHER: Proficiency-Based Progression simulation training|OTHER: Traditional simulation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ziprasidone And Olanzapine's Outcomes In Mania
Status: TERMINATED
Conditions: Acute Mania|Bipolar Disorder, Manic
Interventions: DRUG: ziprasidone hydrochloride|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Shingles|Herpes Zoster|Neuropathic Pain
Interventions: DRUG: KD7040 Topical Gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide Receptor Radionuclide Therapy (PRRT) in Tumors With High Expression of Somatostatin Receptors (Phase 2)
Status: UNKNOWN
Conditions: Neuroendocrine Tumors|Peptide Receptor Radionuclide Therapy (PRRT)
Interventions: RADIATION: Lutetium-177 (177Lu)-DOTATOC|RADIATION: Yttrium-90 (90Y)-DOTATOC|RADIATION: 177Lu-DOTATOC + 90Y-DOTATOC|RADIATION: Re-treatment 177Lu-DOTATOC|RADIATION: Re-treatment 90Y-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF
Status: COMPLETED
Conditions: Atrial Fibrillation|Prescribing Practices|Anticoagulants
Interventions: BEHAVIORAL: Anticoagulation (AC) Intervention--Academic Detailing|BEHAVIORAL: Anticoagulation (AC) Intervention--Prescribing Practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali
Status: RECRUITING
Conditions: Malaria,Falciparum
Interventions: DRUG: TB31F|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients
Status: RECRUITING
Conditions: Pediatric Cancer
Interventions: OTHER: "Just Move" Exercise|OTHER: Standard of Care Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Medacta International SMS Post-Marketing Surveillance Study
Status: RECRUITING
Conditions: Arthrosis|Traumatic Arthritis|Rheumatoid Polyarthritis|Congenital Hip Dysplasia|Avascular Necrosis of the Femoral Head
Interventions: DEVICE: SMS femoral stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia
Status: COMPLETED
Conditions: COPD|Cachexia
Interventions: DIETARY_SUPPLEMENT: Nutrifriend Cachexia|DIETARY_SUPPLEMENT: Isocaloric placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tibolone Endometrium Study (Study 32972)(P06470)
Status: COMPLETED
Conditions: Postmenopausal Women
Interventions: DRUG: tibolone|DRUG: Tibolone 2.5 mg|DRUG: CE/MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase 3 Trial to Evaluate the Efficacy and Safety of YYC506.
Status: UNKNOWN
Conditions: Dyslipidemias
Interventions: DRUG: YYC506|DRUG: Control|DRUG: YYC506 Placebo|DRUG: Control Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery
Status: RECRUITING
Conditions: Orthopedic Disorder|Total Knee Replacement|Post Operative Pain|Surgery
Interventions: PROCEDURE: Combine Adductor Canal & Sciatic Nerve Block|PROCEDURE: Combine Femoral & Sciatic Nerve Block|DRUG: Bupivacaine and prilocaine hydrochloride|DRUG: Bupivacaine and prilocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-operative Adjuvant Therapy w/wo GammaTile + Systemic Therapy
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: DEVICE: Gamma Tile-Surgically Targeted Radiation Therapy (STaRT)|RADIATION: Stereotactic Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intralesional Injection Of Methotrexate Versus Triamcinolone Acetonid In Treatment Of Localized Psoriasis
Status: UNKNOWN
Conditions: Localized Psoriasis
Interventions: DRUG: Intralesional Injection of Methotrexate|DRUG: Triamcinolone Acetonid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of TNX-201 Capsules for Treatment of Single Tension-Type Headache
Status: COMPLETED
Conditions: Tension-Type Headache
Interventions: DRUG: TNX-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foot Spine Syndrome "RAFFET Syndrome"
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain|Hallux Rigidus
Interventions: OTHER: manual therapy and exercise for the big toe|OTHER: lumbar stabilization exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
Status: TERMINATED
Conditions: Venous Ulcers
Interventions: DRUG: Nitric Oxide 200ppm Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Efalizumab - anti-CD11a recombinant human monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of PAC-14028 Cream in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PAC-14028|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Mepilex Ag vs. Xeroform in Pediatric Patients That Sustain Partial Thickness Burn Injury
Status: WITHDRAWN
Conditions: Second-degree Burn
Interventions: DEVICE: Mepilex Ag (burn dressing)|DEVICE: Xeroform Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Automated Geriatric Co-Management Program in Older Patients With Solid Mass or Nodule Suspicious for Cancer
Status: TERMINATED
Conditions: Cancer
Interventions: OTHER: in-person geriatric co-management|OTHER: automated geriatric co-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder|Bipolar Disorder|Dysthymia
Interventions: OTHER: Mental Health Telemetry (MHT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Platinum-Based Chemotherapy Plus Ramucirumab in Patients With Advanced NSCLC Who Have Progressed on First Line Anti-PD-1 Immunotherapy
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Diabetes
Status: RECRUITING
Conditions: Diabetes
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychodynamic Motivation and Training Program
Status: COMPLETED
Conditions: Coronary Heart Disease|Physical Activity
Interventions: BEHAVIORAL: Psychodynamic Motivation and Training Program (PMT)|BEHAVIORAL: Advice in Exercise Training (+Ex)|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia
Status: COMPLETED
Conditions: Cesarean Section Complications|Spinal Anesthesia
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Severe Intrauterine Growth Retardation: Developmental Newborn Intensive Care Unit (NICU) Care
Status: COMPLETED
Conditions: Intrauterine Growth Retardation|Prematurity
Interventions: BEHAVIORAL: Newborn Individualized Developmental Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Protein Diet Supplemented Keto-/Amino Acid in Preventing the Progression of Chronic Kidney Disease (CKD)- ELPD Study
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: low protein diet plus α-keto acid|BEHAVIORAL: very low protein diet plus α-keto acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Approach To Improving Lactation Support With Mobile Health Technology
Status: COMPLETED
Conditions: Breastfeeding|Feeding Behavior
Interventions: OTHER: EpxBreastfeeding|OTHER: Baby book survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Hygiene and Connected Toothbrush Before Alveolar Bone Graft for Cleft Lip and Palate
Status: WITHDRAWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Ara® KOLIBREE tooth brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Massage Therapy in Treating the Symptoms of Patients With Locally Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: management of therapy complications|PROCEDURE: massage therapy|PROCEDURE: pain therapy|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery
Status: RECRUITING
Conditions: Myocardial Injury|Non-cardiac Surgery|Remote Ischemic Preconditioning
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham-remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Adding Auditory Information on Head Movements in People With Traumatic Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Whiplash|Healthy
Interventions: DEVICE: Smartphone playing a sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
Status: COMPLETED
Conditions: Lumbar Spondylosis|Cervical Spondylosis|Hip Osteoarthritis|Knee Osteoarthritis
Interventions: DRUG: inhalation anesthesia with isoflurane vs. TIVA with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Single-Dose Gabapentin in Transient Insomnia Induced by a Sleep Phase Advance
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets
Status: COMPLETED
Conditions: Healthy Volunteers|Type 2 Diabetes
Interventions: DRUG: Oral semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Performance of 59% Hioxifilcon A Contact Lenses vs. Marketed Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Refractive Error - Myopia Bilateral
Interventions: DEVICE: Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability Study of Loratadine 10 mg Tablets
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Loratadine 10 mg Tablets Under Fasting Conditions (Sandoz, Inc.)|DRUG: Loratadine 10 mg Tablets Under Fed Conditions (Sandoz, Inc.)|DRUG: Claritin (Loratadine) 10 mg Tablets Under Fed Conditions (Schering)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bolus Administration of Intravenous Lidocaine at the Time of Abdominal Hysterectomy
Status: COMPLETED
Conditions: Abdominal Hysterectomy
Interventions: DRUG: lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tonsillar Cytokine Expression After Allergen and/or Virus Intervention
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: Timothy, Phleum pretense|BIOLOGICAL: Live attenuated influenza virus|PROCEDURE: Timothy + attenuated influenza virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of XTR006 PET Imaging in Non-cognitively Impaired Subjects, MCI Due toAD, and Mild to Moderate AD Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: XTR006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Seraprevir in Combination With Sofosbuvir in Chronic Genotype 1 Hepatitis C Virus Infection Patients
Status: UNKNOWN
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Seraprevir|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incremental Haemodialysis in Incident Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Disease, End-Stage
Interventions: PROCEDURE: Incremental haemodialysis|PROCEDURE: Conventional haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two Part Trial Investigating an Anti-obesity Drug in Overweight/Obese Male and Female Healthy Volunteers
Status: TERMINATED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC 0070-0002-0453|DRUG: '2-0453|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh.
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Xalacom
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine, Mitoxantrone and Rituximab in Relapsed or Primary Failing Advanced Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: rituximab|DRUG: fludarabine|DRUG: mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Intradialytic Symptoms in Subjects Treated With Qd 500vs Qd 300
Status: COMPLETED
Conditions: End Stage Renal Disease on Dialysis
Interventions: DEVICE: Dialysate Flow Rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Angiomax in Patients With HIT/HITTS Type II Undergoing CPB
Status: COMPLETED
Conditions: Cardiovascular Disease|Coronary Artery Bypass Surgery
Interventions: DRUG: Angiomax (bivalirudin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Toothpaste to Reduce Plaque and Inflammation
Status: COMPLETED
Conditions: Plaque|Inflammation
Interventions: OTHER: Plaque identifying toothpaste|OTHER: Non-plaque identifying toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined Pharmacotherapies for Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Ondansetron 4 ug/kg b.i.d. + Cognitive Behavioral Therapy|DRUG: Naltrexone 50 mg/day + Cognitive Behavioral Therapy|DRUG: Ondansetron 4 ug/kg b.i.d.+ Naltrexone 50 mg/day + Cognitive Behavioral Therapy|OTHER: Placebo + Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Navigation-Assisted Dental Implant Placement
Status: COMPLETED
Conditions: Dental Implants, Surgery, Computers
Interventions: DEVICE: Dynamic Navigation Assisted Implant Surgery|PROCEDURE: Freehand Implant Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Salsalate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Examining the Long Term Safety, Efficacy, and Corticosteroid-sparing Effect of Certolizumab Pegol in Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapalene-Benzoy Peroxide (BPO) Gel in the Treatment of Acne Vulgaris as a 6-month Maintenance
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electro-acupuncture for Long Covid Neuropsychiatric Symptoms
Status: RECRUITING
Conditions: Long Covid19|Neuropsychiatric Symptoms|Electro-acupuncture
Interventions: DEVICE: Acupuncture|DEVICE: Sham-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: intermediate dose Enoxaparin/ unfractionated heparin|DRUG: standard prophylactic dose Enoxaparin/ unfractionated heparin|DRUG: Atorvastatin 20mg|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids, Learning, and Memory
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis|Psychotic Disorders
Interventions: DRUG: THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Efficacy and Safety of Risperidone Versus Risperidone Plus Low Dose of Haloperidol in the Treatment of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain in COVID-19 Patients Discharged From Intensive Care Unit
Status: COMPLETED
Conditions: COVID-19 Pandemic|ICU|Pain, Chronic|Post Intensive Care Unit Syndrome|Neuropathic Pain
Interventions: OTHER: Pain and neuropsychological questionnaires|DIAGNOSTIC_TEST: Quantitative Sensory testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Proprioceptive Training on Neurofunctional Control and Ankle Sprains Incidence
Status: UNKNOWN
Conditions: Ankle Injuries
Interventions: OTHER: Proprioceptive Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women With Osteopenia, 45 Years of Age and Older
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: Zoledronic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin Cancer
Status: COMPLETED
Conditions: Recurrent Skin Cancer|Squamous Cell Carcinoma of the Skin
Interventions: BIOLOGICAL: cetuximab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, PK and Efficacy of HS-10296 in Patients With NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonsmall Cell Lung Cancer
Interventions: DRUG: HS-10296
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DEVICE: Transcranial Magnetic Stimulation (active)|DEVICE: Transcranial Magnetic Stimulation (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restrictive vs Goal Directed Fluid Therapy During Hepatobiliary Surgery
Status: COMPLETED
Conditions: Liver Surgery
Interventions: PROCEDURE: GDFT|PROCEDURE: LOW CVP (restrictive group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome Characterized by Constipation
Interventions: DRUG: Linaclotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention With Legume Kernel Fibre in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: pure fibre-product|DIETARY_SUPPLEMENT: reference fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Status: UNKNOWN
Conditions: Pruritus|Kidney Failure, Chronic
Interventions: DEVICE: Laser acupuncture (Olympic)|DEVICE: Sham Laser acupuncture (Olympic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Transparent Silicone Membrane With Physical Microstructure for Second-degree Burn Wounds and Skin Graft Wounds
Status: NOT_YET_RECRUITING
Conditions: Second-degree Burn Wounds|Skin Graft Wounds
Interventions: DEVICE: Physical microstructure-modified transparent silicone film sheet|DEVICE: Decellularized pig skin|DEVICE: Vaseline gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Poziotinib in Japanese Patients With NSCLC
Status: TERMINATED
Conditions: NSCLC
Interventions: DRUG: Poziotinib Once Daily Dosing|DRUG: Poziotinib Twice Daily Dosing|DRUG: Poziotinib Once Daily Dosing or Twice Daily Dosing as determined in Phase 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Colchicine After PCI
Status: NOT_YET_RECRUITING
Conditions: Coronary Heart Disease|Percutaneous Coronary Intervention|Colchicine
Interventions: DRUG: Colchicine 0.5 mg|DRUG: Colchicine 0.375 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Use of Artificial Intelligence (Fujifilm) for Polyp Detection in Colonoscopy
Status: RECRUITING
Conditions: Screening Colonoscopy|Colonoscopic Control After Polypectomy|Suspected Colon Polyps
Interventions: PROCEDURE: colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HDR Brachytherapy 68-Ga-RM2 PET, 68-Ga-PSMA-11 PET &Multi Parametric MRI in Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: 68-Ga RM2.|DRUG: 68-Ga PSMA11|DEVICE: PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement
Status: RECRUITING
Conditions: Salivary Duct
Interventions: DRUG: Postoperative Oral Antibiotics (Clindamycin or Augmentin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Pemetrexed plus Pembrolizumab|DRUG: Pembrolizumab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain.
Status: COMPLETED
Conditions: Acute Non-cardioembolic Ischemic Stroke
Interventions: DRUG: BAY2433334|OTHER: BAY2433334 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium Metabolism in Asian Adolescents
Status: COMPLETED
Conditions: Bone Mineralization|Adolescent Development
Interventions: DIETARY_SUPPLEMENT: Beverage containing calcium citrate malate|DIETARY_SUPPLEMENT: Beverage fortified with calcium citrate malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDER
Status: COMPLETED
Conditions: Membranous Ventricular Septal Defects
Interventions: DEVICE: AMPLATZER Membranous VSD Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation in Upper Extremity Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Quality of Life|Lymphedema|Hand Grasp|Grip|Strength|Edema
Interventions: OTHER: Complex Decongestive Treatment|OTHER: Sham transcutaneous vagus nerve stimulation|OTHER: Transcutaneous Auricular Vagus Nerve Stimulation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PHP-201 0.5% ophthalmic solution (topical eye drop)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Nasal Mask vs Nasal Prong on Pain Response in Neonate
Status: NOT_YET_RECRUITING
Conditions: Nasal Mask|Nasal Prong
Interventions: DEVICE: nasal mask|DEVICE: nasal prong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Allogenic CD123-CAR-NK Cells in the Treatment of Refractory/Relapsed Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia Refractory|Acute Myeloid Leukemia Recurrent
Interventions: BIOLOGICAL: CD123-CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Transcutaneous Electrical Nerve Stimulation After Thoracic Surgery
Status: COMPLETED
Conditions: Thoracic|Surgery|Pain|Pulmonary Function|Functional Capacity
Interventions: OTHER: Physiotherapy rehabilitation and Transcutaneous Electrical Nerve Stimulation|OTHER: Physiotherapy Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PARP Inhibitor Oral Maintenance in Low-Risk Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Epithelial Ovarian Cancer|Ovarian Cancer|Ovarian Cancer Stage III|Ovarian Cancer Stage IV
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics Use For Further Treatment Improvement in childreN
Status: COMPLETED
Conditions: Asthma in Children
Interventions: GENETIC: ADRB2-genotype guided treatment|OTHER: Randomisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Energy-Harvesting Mesofluidic Impulse Prosthesis: e-MIP
Status: WITHDRAWN
Conditions: Transtibial Amputation|Artificial Limbs
Interventions: DEVICE: Habitual Prosthesis|DEVICE: Energy-Harvesting Mesofluidic Impulse Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Role of Amnion Membrane Allografts in Nipple Preservation
Status: NOT_YET_RECRUITING
Conditions: Mastectomy|Gender Affirmation Surgery|Nipple Sparing Mastectomy|Prophylactic Mastectomy|Benign Breast Condition
Interventions: DEVICE: AmnioFix dehydrated Human Amnion/Chorion Membrane Allograft|DEVICE: Control Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Venous Thromboembolism Prevention in Outpatients With Glioma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma|Astrocytoma|Venous Thromboembolism
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plant Stanols and Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DIETARY_SUPPLEMENT: Vegetable oil based margarine with plant stanol ester enrichment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Versus Comprehensive Care for Post Acute Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: OTHER: Comprehensive care|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long COVID-19 Syndrome in Primary Care: A Novel Protocol of Exercise Intervention "CON-VIDA Clinical Trial"
Status: UNKNOWN
Conditions: COVID-19|Long COVID|Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Virus Plus Anti-PD1 and Chemotherapy as Preoperative Therapy for Patients With BRPC/LAPC
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Oncolytic virus Plus Anti-PD1 and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Phone-based Intervention for Promoting Healthy Habits and Weight Loss
Status: UNKNOWN
Conditions: Diabetes|Hypertension|Pre-diabetes|Overweight|Obese|Weight|Adherence
Interventions: OTHER: Stress Reduction& Healthy living
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome
Status: RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: zatolmilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus
Status: COMPLETED
Conditions: Cutaneous Lupus Erythematosus
Interventions: DRUG: CC-11050|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
Status: COMPLETED
Conditions: Open Wound Abdominal Wall|Wound Non Healing
Interventions: DEVICE: NPWT Standard of Care plus Oasis wound product|DEVICE: Routine NPWT Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroregenerative Potential of Intravenous G-CSF and Autologous Peripheral Blood Stem Cells
Status: COMPLETED
Conditions: Neurodegeneration|G-CSF|Peripheral Blood Mononuclear Cells|Cerebral Palsy
Interventions: BIOLOGICAL: Peripheral blood mononuclear cells (mPBMC)|DRUG: G-CSF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD7-Specific CAR-T Cells
Status: COMPLETED
Conditions: T-cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions: BIOLOGICAL: CD7 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT