pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of HEC96719 in Subjects With Non-Cirrhotic Non-Alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DRUG: HEC96719|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Testing TH-302 in Combination With Gemcitabine in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma
Interventions: DRUG: TH-302|DRUG: Gemcitabine|DRUG: Placebo (5 percent dextrose - D5W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimum Dose Computed Tomography of the Thorax for Follow-up in Patients With Resected Lung Carcinoma
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: Minimum Dose Computed Tomography (MnDCT) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV
Status: RECRUITING
Conditions: HIV Infections|Cognitive Impairment
Interventions: BEHAVIORAL: Phase 1 Gym Exercise HIIT|BEHAVIORAL: Phase 1 Gym Exercise CME|BEHAVIORAL: Phase 2 Home Exercise Coaching Text Messages|BEHAVIORAL: Phase 2 Home Exercise Control Text Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese Women
Status: COMPLETED
Conditions: Body Weight|Visceral Obesity
Interventions: DIETARY_SUPPLEMENT: Hydroxytyrosol|OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Polymer-based sirolimus-eluting stent (Partner stent )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer
Status: COMPLETED
Conditions: Anal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: Radiation Therapy (XRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Use in Oral Iron Replacement Deficiency Anemia Patients Initiating Oral Iron Replacement
Status: COMPLETED
Conditions: Iron Deficiency Anemia Treatment|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum 299v probiotic support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Atorvastatin Treatment in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Atorvastatin|DRUG: Formoterol|DRUG: Lactose tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Laryngopharyngeal Sensation in Adductor Spasmodic Dysphonia
Status: COMPLETED
Conditions: Spasmodic Dysphonia|Adductor Spasmodic Dysphonia|Voice Disorders
Interventions: DEVICE: Sensation testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Probiotics on Workplace Related Stress Symptoms
Status: COMPLETED
Conditions: Stress|Sleep Disorder
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Celecoxib on Electrophysiological Property in Brain of Healthy Volunteer
Status: COMPLETED
Conditions: Electrophysiologic Property of Brain
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Selenium Supplementation in Autoimmune Thyroiditis
Status: COMPLETED
Conditions: Autoimmune Thyroiditis
Interventions: DIETARY_SUPPLEMENT: SelenoPRECISE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess the Efficacy of Botulinum Toxin B on Pain and Disability in Subjects With Acute Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain
Interventions: DRUG: Botulinum toxin B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Personalized Sound Intervention During Autogenous Gingival Grafts in Adults
Status: RECRUITING
Conditions: Music Intervention|Gingival Graft|Anxiety|Pain|Dissatisfaction
Interventions: OTHER: personalized music intervention|OTHER: selected audio book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemo-Radiotherapy Versus Radiotherapy With Boost in Locally Advanced Unresectable Rectal Cancers
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Chemoradiation|RADIATION: Additional Radiation boost to the primary tumor volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurokinin (NK) 1 Antagonist for Pathological Aggression for Harmful, Impulsive, and Self-/Aggressive Behaviour
Status: UNKNOWN
Conditions: Aggression
Interventions: DRUG: NK1 Antagonist|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bioptron Light Therapy (BLT) on Post Chemotherapy Oral Mucositis
Status: COMPLETED
Conditions: Oral Mucositis (Ulcerative)
Interventions: OTHER: Bioptron Light Therapy (BLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectivity of Inspiratory Muscle Trainer in the Chronic Obstructive Pulmonary Disease Rehabilitation Program
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Inspiratory Muscle Trainer Philips Respironics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic Education for Children in an Emergency Care Unit
Status: COMPLETED
Conditions: Otorhinolaryngologic Diseases|Respiratory Tract Infections|Pyelonephritis|Urinary Tract Infections
Interventions: OTHER: antibiotic education for children in an emergency care unit|OTHER: antibiotic education for children in an emergency care unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of the Be Mindful Intervention in Previously Depressed Individuals Experiencing Subclinical Symptoms
Status: COMPLETED
Conditions: Depressive Symptoms|Major Depressive Disorder, Recurrent, in Remission
Interventions: BEHAVIORAL: Be Mindful
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Implant of metaphyseal sleeves in Total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Metastatic Squamous Cell Carcinoma of the Hypopharynx|Metastatic Squamous Cell Carcinoma of the Larynx|Metastatic Squamous Cell Carcinoma of the Oral Cavity|Metastatic Squamous Cell Carcinoma of the Oropharynx|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVC Hypopharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7|Stage IVC Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7|Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Docetaxel|DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer
Status: NOT_YET_RECRUITING
Conditions: Bile Duct Cancer
Interventions: DRUG: Gemcitabin, Cisplatin and Durvalumab|PROCEDURE: Biliary Radiofrequency Ablation|PROCEDURE: Endoscopic Retrograde Cholangio-Pancreatography with stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Analogue Treatment in Uncontrolled Type 1 Diabetic Patients
Status: UNKNOWN
Conditions: Uncontrolled Type 1 Diabetic Patients
Interventions: DRUG: liraglutide|DRUG: Insulin injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Protective Ventilation for Obese Patients Undergoing Gynaecological Laparoscopic Surgery
Status: COMPLETED
Conditions: Anesthesia|Surgery--Complications
Interventions: DRUG: Intravenous anesthetic|DRUG: Crystalloid Solutions|DIAGNOSTIC_TEST: Esophageal pressure measurement|DIAGNOSTIC_TEST: Lung volume measurement with the nitrogen washin-washout technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Marqibo in Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Marqibo® (vincristine sulfate liposomes injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treat-to-target by Email During Urate-lowering Therapy in Gout
Status: RECRUITING
Conditions: Gout|Inflammatory Rheumatism|Hyperuricemia|Posology Adjustment
Interventions: OTHER: Cleanweb electronic messaging ePro|OTHER: Usual follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Potential Anti-tumor Effects of SSGJ-705 in Patients With Advanced or Metastatic HER2-expressing Solid Tumors
Status: UNKNOWN
Conditions: Receptor, ErbB-2
Interventions: DRUG: SSGJ-705
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3305677 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3305677|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylactic LYMphatic Reconstruction (LYMbR) to Prevent Lymphedema After Node Dissection for Cutaneous Malignancies
Status: NOT_YET_RECRUITING
Conditions: Lymphedema of Limb|Malignant Skin Neoplasm
Interventions: PROCEDURE: Prophylactic lymphaticonvenous anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Autoimmune Diseases
Interventions: BIOLOGICAL: Assigned Interventions CD19/BCMA CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omitting vs. Doing Intraoperative Frozen Section Biopsy for Margin Status in Breast Conserving Surgery
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Omission of intraoperative frozen section biopsy for margin status|PROCEDURE: Frozen section biopsy for margin status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Comparative Blinded Trial of Several HIV-1 Derived Immunogens in Infected Individuals With >= 500 CD4 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Aluminum hydroxide|BIOLOGICAL: MF59|BIOLOGICAL: rgp120/HIV-1IIIB|BIOLOGICAL: rgp120/HIV-1MN|BIOLOGICAL: rgp120/HIV-1 SF-2|BIOLOGICAL: Env 2-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Evaluation of 2 Resection Strategies of Synchronous Colorectal Cancer Metastases
Status: TERMINATED
Conditions: Colorectal Cancer|Hepatic Metastases
Interventions: PROCEDURE: Simultaneous surgery|PROCEDURE: Sequential surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of LY2189265 on Glycemic Control in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2189265 and Lifestyle Measures|DRUG: Placebo solution and Lifestyle Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease
Status: COMPLETED
Conditions: Chorea, Huntington
Interventions: DRUG: Valbenazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Action Observation Therapy and Video-Based Play Therapy on Children With Unilateral Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy|Upper Extremity Problem
Interventions: OTHER: Action Observation Treatment|OTHER: Virtual Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Unresectable Pancreatic Cancer|Metastatic Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Renal Failure in People Followed for Type 2 Diabetes in General Practice
Status: NOT_YET_RECRUITING
Conditions: Renal Insufficiency and Diabetes Mellitus
Interventions: OTHER: training and audit|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Know Your Pulse Post Stroke-Measurement of Peripheral Pulse for Detection of Atrial Fibrillation After Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Atrial Fibrillation
Interventions: BEHAVIORAL: Measurement of peripheral pulse|DEVICE: 72h holter ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect Of Position On Laryngeal Visualisation With The C-Mac Videolaryngoscope
Status: COMPLETED
Conditions: Anesthesia|Intubation|Laryngoscopy
Interventions: DEVICE: C-MAC videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
Status: RECRUITING
Conditions: Pregabalin|Dexmedetomidine|Delirium
Interventions: DRUG: Pregabalin|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Dream Doctors in Children Undergoing Digestive Endoscopic Procedures
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: PROCEDURE: Sedation of children during gastroscopy with and without the presence of dream doctor|DEVICE: evaluation of stress with PPI and GSR|BIOLOGICAL: blood specimens for stress hormones|OTHER: Physiological indices for evaluation of stress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
Status: COMPLETED
Conditions: Solid Tumors|Brain Tumors|Brain Metastases
Interventions: DRUG: Satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bowel Ultrasound & MR Enterography in the Follow-up of Previously Diagnosed Pediatric Small Bowel Crohn Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: PROCEDURE: Bowel ultrasound|PROCEDURE: magnetic resonance enterography (MRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Gabapentin With Doxepin in the Management of Uremic Pruritus
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: Doxepin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Proton Versus Carbon Ion Radiation Therapy in Patients With Chordoma of the Skull Base
Status: UNKNOWN
Conditions: Chordoma|Tumor|Treatment
Interventions: RADIATION: Carbon ion|RADIATION: Protons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|Bladder Cancer Recurrent|Neoplasm Recurrence|Urothelial Carcinoma Bladder|Urothelial Carcinoma Recurrent|Non-Invasive Bladder Urothelial Carcinoma
Interventions: DRUG: Bacillus Calmette-Guerin: Strain Russian BCG-I|DRUG: Bacillus Calmette-Guerin: Strain TICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shifting Sleep Timing in Teens
Status: RECRUITING
Conditions: Sleep Insufficiency|Sleep|Adolescent Behavior
Interventions: DEVICE: Light|BEHAVIORAL: CBT|DEVICE: Sham Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pirfenidone Capsules in the Treatment of Pneumoconiosis
Status: NOT_YET_RECRUITING
Conditions: Pneumoconiosis
Interventions: DRUG: Pirfenidone Capsules|DRUG: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Hyoscine Butylbromide Injection on First Stage Labour in Primigavidae
Status: COMPLETED
Conditions: Vaginal Delivery
Interventions: DRUG: hyoscine butylbromide|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A: Mavacamten intact oral capsule|DRUG: Treatment B: Mavacamten open capsule in suspension|DRUG: Treatment C: Mavacamten open capsule in suspension administered via nasogastric tube (NGT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanol-Lock Treatment in Preventing Central Venous Catheter Infections in Patients With High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Bevacizumab Plus Chemotherapy in EGFR-TKI Resistant Non-Squamous Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung, Carcinoma
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: metformin, topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Treg/Tcon Addback to Partially Matched Related Donor Stem Cells With Myeloablative Conditioning and Post-transplant Cyclophosphamide for High Risk Hematologic Malignancies
Status: TERMINATED
Conditions: High Risk Hematologic Malignancies
Interventions: BIOLOGICAL: stem cell transplant|PROCEDURE: Stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: 400 µg Brimonidine Tartrate Implant|DRUG: 200 µg Brimonidine Tartrate Implant|DRUG: 100 µg Brimonidine Tartrate Implant|OTHER: Sham (no implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency
Status: TERMINATED
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: MOD-4023|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of HM11260C in Adult Obesity Patients Without Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DRUG: HM11260C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin for COVID-19-Induced Taste or Smell Abnormality
Status: WITHDRAWN
Conditions: Covid19|Taste Disorder, Secondary|Taste Disorders|Dysgeusia|Smell Disorder|Ageusia|Anosmia
Interventions: DIETARY_SUPPLEMENT: Lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Statins, Ezetimibe and Nutraceuticals
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: statin + ezetimibe|DRUG: statin + ezetimibe + Nutraceuticals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-67571244 in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: JNJ-67571244
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Different Doses of BIRB 796 BS in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: BIBR 796 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex Difference in Preemptive Analgesic Effects With Flurbiprofen Axetil on Postoperative Pain and Sleep Quality
Status: UNKNOWN
Conditions: Preemptive Analgesia|Sex Difference|Flurbiprofen Axetil|Postoperative Pain|Postoperative Sleep Quality
Interventions: DRUG: preemptive analgesia with flurbiprofen axetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Measurement of Cardiac Output by the NEXFIN HD Monitor in Peroperative
Status: COMPLETED
Conditions: Cardiac Output|Peroperative
Interventions: DEVICE: Intraoperative heart rate measurement (reference method)|DEVICE: NEXFIN HD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Early PCI for STEMI
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Coronary Artery Disease
Interventions: PROCEDURE: Complete Revascularization Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Cuff Closure Time Using Unidirectional Barbed Suture in Robotic Hysterectomy
Status: UNKNOWN
Conditions: Disease (or Disorder); Gynecological
Interventions: DEVICE: Unidirectional Barbed Suture (V-Loc)|DEVICE: polyglactin 910 (Vicryl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: dexamethasone|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baduanjin Versus Brisk Walking for Cognition in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Exercise|Condition
Interventions: BEHAVIORAL: Baduanjin exercsie|BEHAVIORAL: Brisk walking|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol and Perioperative Inflammation
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: propofol|DRUG: Intralipid 10%|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effects of Sevoflurane and Desflurane on QT Interval Measured With Cardiac Electrophysiological Balance Index
Status: UNKNOWN
Conditions: Sevoflurane|Desflurane|QT Interval|Electrophysiological Balance Index
Interventions: DIAGNOSTIC_TEST: 12- derivation Electrocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Diamond Bur Microblepharoexfoliation, Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: PROCEDURE: Microblepharoexfoliation|PROCEDURE: Intense pulse light|PROCEDURE: Meibomian gland expression|DRUG: Home-based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Laser Assisted Delivery of Anesthetics
Status: COMPLETED
Conditions: Local Anesthesia of the Skin.
Interventions: DEVICE: AFXL|DRUG: AHES|DRUG: EMLA cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of an Oral Beta-2 Agonist in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: extended release beta-2 adrenergic agonist|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assesment of the Efficiency and Safety Helicobacter Pylori Therapy With or Without Saccharomyces Boulardii
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Saccharomyces boulardii|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducational Intervention for ICD Patients (PEACE)
Status: COMPLETED
Conditions: Heart Failure|Ventricular Arrhythmias
Interventions: BEHAVIORAL: Psychoeducational Telephone counseling (TC)|BEHAVIORAL: Psychoeducational Intervention by Group (SG)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrathecal Transplantation Of Autologous Adipose Tissue Derived MSC in the Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: autologous adipose tissue derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of PCL With EUS-FNA and Cross-sectional Imaging - A Report of Accuracy
Status: UNKNOWN
Conditions: Pancreatic Cyst|Pancreatic Neuroendocrine Carcinoma|Pancreatic Pseudocyst|Pancreatic Serous Cystadenoma|Pancreatic Mucinous Cystadenoma|Pancreatic Cystadenocarcinoma|Pancreatic Intraductal Papillary-Mucinous Neoplasm|Solid Pseudopapillary Tumor of the Pancreas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: [68Ga]Ga-NeoB|DRUG: [177Lu]Lu-NeoB|DRUG: Ribociclib|DRUG: Fulvestrant|OTHER: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Registry on the HARPOON Device
Status: TERMINATED
Conditions: Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse
Interventions: DEVICE: HARPOON Beating Heart Mitral Valve Repair System (MVRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Naltrexone SR 16 mg/Bupropion SR 360 mg /day|DRUG: Naltrexone SR 32 mg/Bupropion SR 360 mg /day|DRUG: Placebo|BEHAVIORAL: Ancillary therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AdCh63 ME-TRAP and MVA ME-TRAP Malaria Vaccines Evaluation in Healthy Adults and Children in a Malaria Endemic Area
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: HDCRV|BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP, MVA ME-TRAP|BIOLOGICAL: HDCRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lamotrigine 25 mg Chewable Tablets, Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine 25 mg Chewable Tablets|DRUG: Lamictal® 25 mg Chewable Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic Pathways
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: erythromycin lactobionate|DRUG: Atropine|DRUG: Erythromycin with atropine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation
Status: COMPLETED
Conditions: Fracture of Tibia Proximal Plateau
Interventions: OTHER: Weight bearing as tolerated|OTHER: Pragmatic Exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aromatherapy on Anxiety and Pain During Dental Treatment in Adults
Status: RECRUITING
Conditions: Dental Anxiety
Interventions: OTHER: Aroma diffuser with single-note sweet orange essential oil|OTHER: Aroma diffuser with single-note tea tree essential oil|OTHER: Aroma diffuser with water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Associated With a Positive SARS-CoV-2 Serology in Contact Subjects at High/Moderate Risk of Coronavirus SARS-CoV-2 Infection. COVID19.
Status: SUSPENDED
Conditions: Coronavirus
Interventions: DIAGNOSTIC_TEST: Serology|GENETIC: Sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Status: TERMINATED
Conditions: Colitis, Ulcerative
Interventions: DRUG: LY3471851|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OPIE in the Thin Interventricular Septum
Status: ENROLLING_BY_INVITATION
Conditions: Hypertrophic Cardiomyopathy
Interventions: DEVICE: on-pump intracardiac echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Preoperative Anxiety on Postoperative Outcome and Sleep Quality in Patients Undergoing Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: General Anesthesia|Postoperative Pain|Postoperative Sleep Quality|Preoperative Anxiety
Interventions: PROCEDURE: patients undergoing gynecological surgery under general anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw
Status: RECRUITING
Conditions: Flat Feet|Flexor Tendon Rupture|Tibialis Posterior Dysfunction|Deformity, Foot
Interventions: PROCEDURE: medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with metal/Bio-Tenodesis screws|PROCEDURE: medializing calcaneal osteotomy and/or transfer of the flexor digitorum longus tendon (FDL) with Shark Screws®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lactoferrin for the Treatment of Symptomatic Uncomplicated Diverticular Disease
Status: UNKNOWN
Conditions: Diverticular Disease|Symptomatic Uncomplicated Diverticular Disease
Interventions: DIETARY_SUPPLEMENT: Lactoferrin CRX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: denufosol tetrasodium (INS37217) Inhalation Solution|DRUG: Placebo - 0.9% w/v sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Relief by Intra-Peritoneal Nebulization of Ropivacaine Under Remifentanil Anesthesia for Gynecological Laparoscopy
Status: COMPLETED
Conditions: Gynecological Laparoscopy
Interventions: DRUG: 10 mLRopivacaine 1%|DRUG: Water for injection|DRUG: 10 mL Ropivacaine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients
Status: RECRUITING
Conditions: Post-Lung Transplantation Bronchiectasis
Interventions: DIAGNOSTIC_TEST: Lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia.
Status: COMPLETED
Conditions: Diphtheria|Acellular Pertussis|Tetanus|Aspergillosis, Allergic Bronchopulmonary|Diphtheria-Tetanus-acellular Pertussis Vaccines
Interventions: OTHER: Pertussis maternal immunization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Auditory Intraoperative Stimulation Effects on Pain and Agitation at Awakening (AUDIOPAW)
Status: COMPLETED
Conditions: Procedural Anxiety|Procedural Pain|Adenotonsillitis
Interventions: BEHAVIORAL: Music|BEHAVIORAL: Mother's lap|BEHAVIORAL: Soundproof earplugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion
Status: UNKNOWN
Conditions: Pericardial Effusion
Interventions: OTHER: Pericardiocentesis with Alteplase|OTHER: Conventional Pericardiocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combination Study With Ridaforolimus (MK8669) and Dalotuzumab (MK0646) in Patients With Advanced Cancer (8669-004)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Comparator: ridaforolimus + dalotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Biomarkers in Patients With Colorectal Cancer and Native KRAS Treated With Chemotherapy + Cetuximab
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI (m)|DRUG: FOLFOX-6 (m)|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Evaluation of Vagal Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer Stage I
Interventions: OTHER: In minimally invasive surgery，Vagus nerve preservation|OTHER: In minimally invasive surgery，Vagus nerve is not preserved
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Cosmetic Outcome of Hypofractionated Versus Normofractionated IMRT in Treatment of Breast Cancer
Status: COMPLETED
Conditions: Tumors|Breast Cancer
Interventions: RADIATION: intensity modulated radiotherapy (IMRT) for breast cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: OTHER: non-intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Move Together Boston Feasibility Pilot (Sit Less, Move More App for Black Breast Cancer Survivors & At-Risk Relatives)
Status: COMPLETED
Conditions: Breast Cancer Survivor|Breast Cancer|Fitness Trackers
Interventions: OTHER: Move Together app/Garmin Activity Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kinesio Taping Technique and Trigger Point
Status: COMPLETED
Conditions: Piriformis Syndrome
Interventions: PROCEDURE: kinesio Tape : Width 5cm ,Length 35cm Y shape
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Intra-Cardiac Echocardiography guided atrial fibrillation ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurological and Psychiatric Comorbidities Patients With FSHD 1 and 2
Status: COMPLETED
Conditions: Muscular Dystrophy, Facioscapulohumeral
Interventions: BEHAVIORAL: Psychiatric test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries|Defective Tooth Restorations
Interventions: DEVICE: Adhese Universal DC|DEVICE: Adhese Universal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Amniotic Membrane or Internal Limiting Membrane for Large or Refractory Macular Holes: A Prospective Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Macular Holes
Interventions: DEVICE: Pars plana Vitrectomy with internal limiting membrane peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma
Status: COMPLETED
Conditions: Recurrent Osteosarcoma
Interventions: DRUG: Glembatumumab Vedotin|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID)
Status: COMPLETED
Conditions: Hepatitis C|People Who Inject Drugs|PWID|HCV Coinfection
Interventions: OTHER: Accessible Care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT