pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Solid Tumor, Adult|Advanced Solid Tumor|Metastatic Tumor|Ovarian Cancer|Ovarian Neoplasms|Ovarian Carcinoma|Metastatic Ovarian Carcinoma|Endometrial Cancer|Endometrial Neoplasms|Endometrial Diseases|Metastatic Endometrial Cancer|Metastatic Endometrial Carcinoma|Advanced Endometrial Carcinoma|Advanced Ovarian Carcinoma|Gastric Cancer|Advanced Gastric Carcinoma|Metastatic Gastric Cancer|Metastatic Gastric Carcinoma|Small-cell Lung Cancer|Small Cell Lung Carcinoma|Triple Negative Breast Cancer|Triple Negative Breast Neoplasms|Platinum-resistant Ovarian Cancer|Platinum-refractory Ovarian Carcinoma|CCNE1 Amplification|Hormone Receptor Negative Breast Carcinoma|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast|Progesterone-receptor-positive Breast Cancer
Interventions: DRUG: NKT3447
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotomy of Optic Nerve in Non-Arthritic Anterior Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Non Arthritic Anterior Ischemic Optic Neuropathy
Interventions: PROCEDURE: optic nerve neurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Resuscitation With Feedback Devices
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: Standard BLS|DEVICE: The CPREazy|DEVICE: TrueCPR|DEVICE: The CPR PRO APP|DEVICE: The CardioPump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Acupuncture Protocols on Vulvodynia
Status: UNKNOWN
Conditions: Vulvodynia|Vulvodynia, Generalized|Vulvar Vestibulitis|Vulvar Pain
Interventions: DEVICE: Acupuncture|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Loss and Gastrostomy Tube Care Outcomes in Head and Neck Cancer Patients With Gastrostomy Tube Placement
Status: UNKNOWN
Conditions: Malnutrition|Gastrostomy
Interventions: OTHER: Nursing Education related to Gastrostomy Tube Care|OTHER: Speech Therapy Education and Evaluation|OTHER: Nutritional Therapy Education and Evaluation|OTHER: Quality of Life Questionnaire C30 version 3|OTHER: Quality of Life Questionnaire EORTC QLO - H&N35
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A-botulinic Toxin for Symptomatic Benign Prostate Hypertrophy
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: BONT-A intra-prostatic injection|DRUG: Optimized medical BPH treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ZT002 in Healthy Participants
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ZT002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Blood Flow Restriction (BFR) Therapy in Post-operative Rehabilitation Following Distal Biceps Tendon Repair
Status: COMPLETED
Conditions: Bicep Tendon Rupture
Interventions: OTHER: Blood Flow Restriction Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraligamentary Injections and Post-endodontic Pain
Status: RECRUITING
Conditions: Pulpitis
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirtuin-NAD Activator in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease (Incl Subtypes)|Dementia
Interventions: DRUG: MIB-626|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mFOLFIRINOX Plus Radiotherapy to Patients With CA19-9-normal Advanced Pancreatic Cancer Refractory to Chemotherapy
Status: RECRUITING
Conditions: Pancreatic Cancer|Radiotherapy
Interventions: DRUG: mFOLFIRINOX plus IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesiotaping on Symptoms, Functional Limitations, and Underlying Deficits of Patients With Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Rotator Cuff Tendinopathy
Interventions: OTHER: Rehabilitation program|DEVICE: Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Oncogenomics (POG) Program of British Columbia
Status: RECRUITING
Conditions: Metastatic Cancers|Advanced Cancers|Cancers That Cannot be Treated With Curative Intent
Interventions: GENETIC: Genome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Goal Directed Hemodynamic Therapy Based on Noninvasive Monitoring in Patients With Hip Fracture
Status: COMPLETED
Conditions: Hip Fractures
Interventions: OTHER: GDT based on noninvasive monitoring|DEVICE: System ClearSight® and Platform EV Clinic 1000®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarctus
Interventions: DRUG: TRO40303|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata|Depressive Episode|Recurrent Depressive Disorder|Anxiety Disorders|Atopic Dermatitis|Allergic Rhinitis|Asthma|Crohn Disease|Ulcerative Colitis|Pernicious Anemia|Type 1 Diabetes|Hashimoto Thyroiditis|Graves Disease|Rheumatoid Arthritis|Psoriatic Arthritis|Ankylosing Spondylitis|Systemic Lupus Erythematosus|Polymyalgia Rheumatica|Sjogren's Syndrome|Psoriasis|Vitiligo|Multiple Sclerosis|Celiac Disease|Upper Respiratory Tract Infection|Influenza|Lower Resp Tract Infection|Acute Bronchitis|Pneumonia|Gastrointestinal Infection|Skin Infection|Urinary Tract Infections|Genital Infection|Herpes Zoster|Herpes Simplex|Infection|Infection Viral
Interventions: OTHER: Exposure of interest (studies 2 & 3).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temocillin vs Meropenem for the Targeted Treatment of Bacteraemia Resistant to Third Gen Cephalosporins
Status: RECRUITING
Conditions: Bacteremia
Interventions: DRUG: Temocillin|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROSpECT-PRIOR-2-CHEMO: PRIOR Dental Intervention Before Chemo to Reduce Chemotherapy Complications
Status: NOT_YET_RECRUITING
Conditions: Oncology|Periodontitis|Myeloma|Oral Mucositis|Febrile Neutropenia
Interventions: PROCEDURE: PRIOR [Proactive Intensive Oral Review & Treatment]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Picosure Alexandrite Laser and Revlite Nd:Yag Laser for the Treatment of Unwanted Tattoos
Status: COMPLETED
Conditions: Unwanted Tattoos
Interventions: DEVICE: Picosure Laser System|DEVICE: Revlite Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
Status: UNKNOWN
Conditions: Pain, Postoperative|ACL
Interventions: DRUG: OxyCODONE 5 mg Oral Tablet|DRUG: Naproxen 500 Mg|DRUG: Tylenol Pill|DRUG: Liposomal bupivacaine|PROCEDURE: Femoral Nerve Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Treatment for Class II Division 1 Malocclusion With Twicare® and Herbst Removable Appliances
Status: TERMINATED
Conditions: Malocclusion, Angle Class II, Division 1
Interventions: DEVICE: Twicare® appliance|DEVICE: Removable Herbst appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation Syndrome
Status: COMPLETED
Conditions: Pseudoexfoliation Syndrome|Pseudoexfoliation Glaucoma in Both Eyes|Pseudoexfoliation of Lens; Glaucoma
Interventions: DIAGNOSTIC_TEST: , Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ziprasidone in the Treatment of Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: ziprasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on the Use of PET-MRI / 68Ga-PSMA Imaging for HIFU-focal Treatment in the Event of Recurrent Prostate Cancer After Radiotherapy - PSMA Study
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Focal HIFU using PET-MRI/68Ga-PSMA imaging guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Sedatives on Tobacco Use Disorder
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: midazolam intravenous infusion|DRUG: placebo intravenous infusion|DRUG: ketamine intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fecal Incontinence Treatment (FIT) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Fecal Incontinence|Bowel Incontinence
Interventions: BEHAVIORAL: Biofeedback|DEVICE: Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2281 in Combination With Liposomal Doxorubicin in Advanced Solid Tumours
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: AZD2281|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fascial Iliac Compartment Block and Quadratus Lumborum Block for Hip Surgery
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: Fascial iliac compartment block|PROCEDURE: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Access to a Primary Care Based Positive Parenting Program
Status: COMPLETED
Conditions: Program Implementation|Child Behavior Problem|Positive Parenting
Interventions: BEHAVIORAL: CARE plus Peer Mentor|BEHAVIORAL: CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Alteplase|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of ADX-N05 for Excessive Daytime Sleepiness in Subjects With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: ADX-N05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Insomnia Study: The Effects of 1 Week of Exercise Training on Insomnia Severity
Status: COMPLETED
Conditions: Insomnia Chronic|Insomnia, Primary
Interventions: BEHAVIORAL: Outdoor Walking|OTHER: Quiet Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating rhIL-11 in Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease|Inflammatory Bowel Disease
Interventions: DRUG: Recombinant Human Interleukin-11 (rhIL-11)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Eye Tracking Technology in the Diagnosis of Neurological Patients
Status: COMPLETED
Conditions: Postcomatose Unawareness State|Minimally Conscious State|Vegetative State|Disorder of Consciousness|Post-Traumatic Coma|Neurological Injury|Traumatic Brain Injury|Diagnosis|Cognitive Dysfunction|Neurological Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily-life Brain Control Of A Hand Exoskeleton After Cervical Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: BNCI controlled hand exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internet Based Cognitive Behavior Treatment for Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorders
Interventions: BEHAVIORAL: Extended self-help program with guidance|BEHAVIORAL: Briefer Self-help program, no guidance|BEHAVIORAL: WL: Extended self-help program, choice of guidance intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Telomelysin (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma
Status: COMPLETED
Conditions: Esophagogastric Adenocarcinoma
Interventions: DRUG: Telomelysin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168
Status: COMPLETED
Conditions: Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Interventions: DRUG: CCX168
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Antihypertensive Agents on Diastolic Function in Patients With Sleep Apnea
Status: COMPLETED
Conditions: Hypertension|Sleep Apnea
Interventions: DRUG: Chlorthalidone plus amiloride|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Nitrate and Bone Study: Effects of Nitrates on Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Nitroglycerin ointment 15 mg/day daily for 24 month|DRUG: Placebo ointment daily for 24 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arterio-arterial Vascular Access as a Novel Technique for Treatment of Venous Hypertention With Arterio-venous Vascular Access
Status: UNKNOWN
Conditions: Vascular Access Complication
Interventions: PROCEDURE: Arterioarterial synthetic graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Vemurafenib Combined With Acitretin in Patients With Advanced Melanoma
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: DRUG: Acitretin|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Patient With Moderate Persistent Asthma II
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: tiotropium Respimat® low dose|DRUG: placebo|DRUG: tiotropium Respimat® high dose|DRUG: 50 mcg salmeterol HFA MDI|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Changes in Hepatic Fat Following Administration of MK-4074 and Pioglitazone Hydrochloride (MK-4074-008)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: MK-4074 200 mg|DRUG: Placebo for MK-4074|DRUG: Pioglitazone hydrochloride 30 mg|DRUG: Placebo for pioglitazone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recurrent Pterygium Surgery Using Mitomycin C With Limbal Conjunctival or Amniotic Membrane
Status: COMPLETED
Conditions: Recurrent Pterygium
Interventions: PROCEDURE: MMC|PROCEDURE: LCAG|PROCEDURE: AMG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychophysiological Characterization of Different Capoeira Performances in Experienced Individuals
Status: COMPLETED
Conditions: Physical Activity|Affective; Reaction|Physiological Stress
Interventions: OTHER: Angola|OTHER: Benguela|OTHER: São Bento
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition
Status: RECRUITING
Conditions: Ultrasound Finding: Ovulation Inhibition, Ovarian Activities|Cervical Mucus|Serum Hormonal Profile
Interventions: DRUG: Estetrol 15 mg/Drospirenone 3 mg (24/4)|DRUG: Ethinylestradiol (EE) 20 mcg/Gestodene 75 mcg (21/7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of High Dose Pancreatic Enzyme Replacement Therapy After Pancreatoduodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy
Interventions: DRUG: Norzyme® 40000 IU|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Theta Burst Brain Stimulation in Diabetic Neuropathy Patients With Neuropathic Pain: Investigating Neural Mechanisms
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: PROCEDURE: Prolonged continuous theta burst stimulation (pcTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Computer Navigation Versus Conventional Total Knee Arthroplasty on Endothelial Damage Marker Levels
Status: UNKNOWN
Conditions: Computer-assisted Navigation Versus Conventional Total Knee Replacement
Interventions: PROCEDURE: Navigation total knee arthroplasty|PROCEDURE: Conventional total knee arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bibliotherapy for Improving Caregiving Appraisal Among Informal Caregivers of People With Dementia: A Pilot RCT
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Bibliotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|Tuberculosis, Multidrug-Resistant|Tuberculosis, MDR|Tuberculosis|Drug-Resistant Tuberculosis
Interventions: DRUG: Pretomanid|DRUG: Bedaquiline|DRUG: Moxifloxacin|DRUG: Pyrazinamide|DRUG: HRZE|DRUG: HR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Treatment With Oral Zolpidem On Polysomnography And Actigraphy Measures In Healthy Volunteers
Status: COMPLETED
Conditions: Methodology Study
Interventions: DRUG: placebo|DRUG: zolpidem|DRUG: zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitrate and Power Output After Two Beetroot Juice Drinks
Status: COMPLETED
Conditions: Blood Plasma Nitrite
Interventions: DIETARY_SUPPLEMENT: Isotonic carbohydrate beetroot juice drink|DIETARY_SUPPLEMENT: Beetroot juice drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Gastrointestinal Emergency Surgery: Evaluation of Morbidity and Mortality
Status: RECRUITING
Conditions: Gastrointestinal Injury|Gastrointestinal Hemorrhage|Gastrointestinal Lesions|Gastrointestinal Ulcer|Gastrointestinal Perforation|Gastrointestinal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Theta Burst Stimulation to Promote Motor Re-education in Tetraplegia
Status: COMPLETED
Conditions: Quadriplegia/Tetraplegia
Interventions: OTHER: Intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
Status: RECRUITING
Conditions: Actinic Keratoses|Aging|Non-Melanoma Skin Cancer
Interventions: DEVICE: Fractionated Laser Resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving the Quality of Care in Nursing Homes
Status: COMPLETED
Conditions: Underperforming Nursing Homes
Interventions: BEHAVIORAL: Continuing Quality Improvement and Quality Assurance system|BEHAVIORAL: CQI and QA System with Best-Practice Care Protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: TVB-2640|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DEVICE: Jet injector|DEVICE: Needle attached dental syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Extracorporeal Shockwave Therapy to Reduce Spasticity in Stroke/CP
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Cerebral
Interventions: DIAGNOSTIC_TEST: Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Nelutri™ on Musculoskeletal Biomarkers in Relative Sarcopenia Adults
Status: COMPLETED
Conditions: Muscular Sarcoidosis
Interventions: DIETARY_SUPPLEMENT: Nelutri™|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZP-3601 SAD and MAD Study in Healthy Subjects and Patients With Hypoparathyroidism
Status: COMPLETED
Conditions: Chronic Hypoparathyroidism
Interventions: DRUG: AZP-3601|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoneurolysis for the Management of Chronic Pain in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Chronic Pain|Osteoarthritis, Knee
Interventions: DEVICE: Cryoneurolysis|OTHER: Neuromuscular exercise (GLA:D)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease
Status: WITHDRAWN
Conditions: Leptomeningeal Metastases
Interventions: OTHER: pharmacological study|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin is an Adjunct to Scaling and Root Planing
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: tablet clarithromycin 500 mg (Clarino-500) orally
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maxillary Sinus Elevation With Bio-Oss or Straumann BoneCeramic
Status: COMPLETED
Conditions: Teeth Loss|Bone Loss
Interventions: DEVICE: Straumann BoneCeramic|DEVICE: Bio-Oss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Global Active Surveillance for Community Acquired Pneumonia
Status: COMPLETED
Conditions: Community Acquired Pneumonia
Interventions: PROCEDURE: Blood draw|PROCEDURE: Chest X-ray|PROCEDURE: urine specimen|PROCEDURE: Nasopharyngeal swab|PROCEDURE: sputum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy and Safety of Medicurtain® in Patients With Total Laparoscopic Hysterectomy (Pivotal Study)
Status: COMPLETED
Conditions: Laparoscopy|Tissue Adhesion, Surgery-Induced|Leiomyoma of the Uterine Body
Interventions: DEVICE: Medicurtain®|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Cataract
Interventions: DEVICE: CyPass Micro-Stent|PROCEDURE: Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: First-line Combination Treatment Based on Anlotinib
Status: UNKNOWN
Conditions: Lung Cancer|Advanced Stage
Interventions: DRUG: Anlotinib，Erlotinib，IBI308，Pemetrexed，gemcitabine，carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: Combination of liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-Arm Multi-Center Study of the HARMONIC® 1100 Shears in Select Devices
Status: COMPLETED
Conditions: Pediatric Procedures|Adult Hepato-pancreato-biliary (HPB) Procedures|Adult Lower Gastrointestinal Procedures|Adult Gastric Procedures|Adult Gynecological Procedures|Adult Urological Procedures|Adult Thoracic Procedures
Interventions: DEVICE: HARMONIC 1100 Shears
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Oxaliplatin, and Capecitabine in Treating Patients With Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin|DRUG: capecitabine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS in People With Subthreshold Depression
Status: NOT_YET_RECRUITING
Conditions: Subthreshold Depression
Interventions: DEVICE: Personalized Experimental Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)|DEVICE: Conventional Experimental Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NAUTILUS: OKI-179 Plus Binimetinib in Patients With Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: RAS Mutation|NRAS Gene Mutation|Melanoma
Interventions: DRUG: OKI-179 + binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Removal of Carotid Body in Patients With Systolic Heart Failure
Status: COMPLETED
Conditions: Systolic Heart Failure|Peripheral Chemoreceptor Hypersensitivity
Interventions: PROCEDURE: Carotid body excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy Surgery
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: vestibular test before and after hippocampal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Mometasone Furoate/Formoterol Combination Versus Formoterol and Mometasone Furoate Alone in Chronic Obstructive Pulmonary Disease (COPD) (Study P04230AM4)(COMPLETED)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Mometasone furoate/formoterol (MF/F) combination|DRUG: Mometasone furoate/formoterol (MF/F) combination|DRUG: Mometasone furoate MDI (MF MDI)|DRUG: Formoterol MDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Properties of CJ-12420 on Evening Dosing
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexlansoprazole 60 MG|DRUG: CJ-12420 50mg|DRUG: CJ-12420 100mg|DRUG: CJ-12420 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theophylline for Treatment of Pseudohypoparathyroidism
Status: ENROLLING_BY_INVITATION
Conditions: Pseudohypoparathyroidism|Pseudohypoparathyroidism Type 1a|Albright Hereditary Osteodystrophy
Interventions: DRUG: Theophylline ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A Injection to Prevent Keloid Recurrence
Status: ACTIVE_NOT_RECRUITING
Conditions: Scar Keloid
Interventions: DRUG: Botulinum Toxin Type A Injection [Botox]|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physiological Response in Lung Transplant Recipients Undergoing Neurally Adjusted Ventilatory Assist
Status: UNKNOWN
Conditions: Work of Breathing|Lung Transplant; Complications|Neurally Adjusted Ventilatory Assist|Ventilator-Induced Lung Injury
Interventions: DEVICE: NAVA ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mid-point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block in Posterolateral Thoracotomy
Status: RECRUITING
Conditions: Bronchiectasis|Lung Neoplasm|Emphysematous Bleb of Lung
Interventions: PROCEDURE: mid-point transverse process to pleura (MTP) block|PROCEDURE: Thoracic Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: estramustine phosphate sodium|PROCEDURE: drug resistance inhibition treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Quantitative Urinary Culture (EQUC) vs Standard Culture (SUC) Techniques in the Clinical Care
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DIAGNOSTIC_TEST: Expanded Urinary Culture|DIAGNOSTIC_TEST: Standard Urine Culture (SUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Increasing Doses of Cystine Binding Thiol Drugs on Cystine Capacity in Patients With Cystinuria
Status: COMPLETED
Conditions: Cystinuria
Interventions: DRUG: Tiopronin 1g per day|DRUG: Tiopronin 2g per day|DRUG: Tiopronin 3g per day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Mechanical Ventilation
Interventions: OTHER: RAGE TXNIP Inflammasome axis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rhythmic Auditory Stimulation on Neural Activity During Finger-tapping in PD Patients
Status: NOT_YET_RECRUITING
Conditions: Acoustic Stimulation|Parkinson Disease|Electroencephalography
Interventions: BEHAVIORAL: noF-noRAS|BEHAVIORAL: F-noRAS|BEHAVIORAL: noF-100RAS|BEHAVIORAL: F-100RAS|BEHAVIORAL: F-105RAS|BEHAVIORAL: F-110RAS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is a Primer Needed for Orthodontic Bonding? A Multi-centre Trial
Status: UNKNOWN
Conditions: Bracket Failure Rate|Bonding Time Per Bracket|Adhesive Remnant Index for Type of Bond Failure|Length of Treatment|Peer Assessment Rating
Interventions: PROCEDURE: No primer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: Saroglitazar magnesium 1 mg|DRUG: Saroglitazar magnesium 2 mg|DRUG: Saroglitazar magnesium 4 mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Hypoxia Before Radioembolization Treatment With 18F-FMISO PET
Status: COMPLETED
Conditions: Radioembolization|Radiotherapy|Cancer|Positron Emission Tomography
Interventions: DIAGNOSTIC_TEST: 18F-Fluoromisonidazole PET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Beta Cell Responsiveness to Glucose-dependent Insulinotropic Polypeptide (GIP) With and Without Sulfonylurea in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SPRiNG: SCIO-469 Patients With Rheumatoid Arthritis Not Receiving Methotrexate
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: SCIO-469|DRUG: SCIO-469|DRUG: Placebo|DRUG: SCIO-469
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Cranberry Beverage on Women With Recent History of Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections|Infection|Urologic Diseases
Interventions: OTHER: cranberry juice|OTHER: placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gamma-delta Tocotrienol as Potential Maintenance Treatment in Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Gamma-Delta Tocotrienol and Tocotrienol Rich Fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pancrelipase on Postprandial Belching and Bloating.
Status: COMPLETED
Conditions: Postprandial Bloating|Postprandial Belching|Postprandial Eructation
Interventions: DRUG: Pancrelipase (Creon) 2 tablets with each meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate PRS-080 in Anemic Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: BIOLOGICAL: PRS-080#022-DP|BIOLOGICAL: PRS-080-Placebo#001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Udenafil in Patient With Pulmonary Arterial Hypertension(PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: udenafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Glimepiride as Oral Anti-Diabetic (OAD) Initiation Mono-therapy in Chinese Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GLIMEPIRIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes
Status: COMPLETED
Conditions: Prediabetes|Depressive Symptoms Mild to Moderate in Severity
Interventions: BEHAVIORAL: Mindfulness-based Personalized Health Planning|OTHER: Structured & Guided Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carbon Monoxide-based Rebreathing Method and Bioimpedance in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Complication|Volume Overload
Interventions: DEVICE: Carbon Monoxide-based Rebreathing|DEVICE: Bioimpedance|RADIATION: Radioactive labelling of erythrocytes and albumin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CerebrAlcare Pills on CereBral Small VesseL DiseasE（CABLE）
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: DRUG: Cerebralcare pills|DRUG: Cerebralcare pills placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Dapagliflozin|DRUG: Lobeglitazone|DRUG: Glimepirde|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiographic Assessment of Bone Dimension Around Immediate Implants With FDBA and I-PRF vs FDBA Alone
Status: ENROLLING_BY_INVITATION
Conditions: Bone Density Increased
Interventions: BIOLOGICAL: i-PRF and FDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trazodone HCl - new polymer|DRUG: Trazodone HCl - Contramid®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Fat and Carbohydrates in Obese Men
Status: COMPLETED
Conditions: Obesity|Steatosis
Interventions: DIETARY_SUPPLEMENT: High fat low carbohydrate diet|DIETARY_SUPPLEMENT: Low fat high carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa
Status: TERMINATED
Conditions: Giant Cell Tumors of Bone
Interventions: DRUG: acid Zoledronic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Endoscopic Submucosal Tunnel Dissection for Superficial Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Superficial Mucosal Lesion
Interventions: PROCEDURE: ESTD|PROCEDURE: ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Personalized Multicomponent Exercise Program in Real Conditions Among Older Adults With HIV
Status: UNKNOWN
Conditions: Frailty|Quality of Life|Physical Inactivity|Body Composition
Interventions: BEHAVIORAL: Personalized multicomponent exercise program (strength, resistance, balance, and flexibility) (PMEP)|OTHER: Body composition|OTHER: Musculoskeletal and visceral Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Quitting Smoking|Smoking Cessation|Smoking, Cigarette
Interventions: BEHAVIORAL: Text message smoking treatment|DRUG: Nicotine replacement therapy sampling|COMBINATION_PRODUCT: Wisconsin Tobacco QuitLine Referral|COMBINATION_PRODUCT: Referral to Primary Care Provider|COMBINATION_PRODUCT: BREATHE 2 Cessation Study|BEHAVIORAL: Additional modalities to learn about and request treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-Escalation Study Evaluating Venetoclax and Azacitidine Discontinuation in AML Responding Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Dilatational Tracheostomy: Ultra-perc Versus Ciaglia Blue Dolphin
Status: COMPLETED
Conditions: ICU Patients Dependant on Mechanical Ventilation : Safest Mode of Performing Percutaneous Tracheostomy Among ICU Ventilated Unweanable Patients
Interventions: PROCEDURE: percutaneous dilatational tracheostomy using Ultra-Perc|PROCEDURE: Percutaneous dilatational tracheostomy using Ciaglia Blue Dolphin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG2451 single dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Oncolytic Virus in Combination With HX-008 and Axitinib in Melanoma Patients With Liver Metastasis
Status: UNKNOWN
Conditions: Melanoma Stage IV
Interventions: DRUG: Recombinant Oncolytic HSV-2 Therapeutic Injecta (Vero Cell) for Human Use (rHSV2hGM-CSF)|DRUG: Recombinant humanized anti-PD-1 monoclonal antibody for injection|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT