pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease Psychosis|Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: FB418
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 2
Status: RECRUITING
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Navigation to clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study
Status: NOT_YET_RECRUITING
Conditions: RECTAL NEOPLASMS|Rectal Cancer
Interventions: RADIATION: Radiotherapy|DRUG: Tislelizumab|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol-Receptor Blockade in Older Men and Women
Status: COMPLETED
Conditions: Normal Healthy Volunteers
Interventions: DRUG: Toremifene|DRUG: Placebo|DRUG: GHRH/Ghrelin combined Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Sofosbuvir/Velpatasvir ± Ribavirin for 12 Weeks in Adults With Chronic HCV Infection and Decompensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Fexofenadine in Subjects Suffering From Seasonal Allergic Rhinitis in Presence of Pollutants
Status: COMPLETED
Conditions: Rhinitis Seasonal
Interventions: DRUG: Fexofenadine M016455|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety With CAR-T for Recurrent or Refractory Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: CD19-targeted CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LISA vs INSURE in the Treatment of Respiratory Distress Syndrome in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Preterm Infants
Interventions: PROCEDURE: Intubate-Surfactant-Extubate(INSURE)|PROCEDURE: less invasive surfactant administration(LISA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BilatEral Hypoglossal Nerve StimulaTion for TreatmEnt of ObstRuctive SLEEP Apnoea With and Without Complete Concentric Collapse
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Genio(TM) bilateral hypoglossal nerve stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Early Borderline Lesions in Low Immunological Risk Kidney Transplant Patients (TRAINING)
Status: RECRUITING
Conditions: Kidney Transplant Failure and Rejection
Interventions: DRUG: Grafalon|DRUG: Normal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth-supported Skills Training for Alcohol-Related Suicidality Phase 3
Status: NOT_YET_RECRUITING
Conditions: Alcohol Drinking|Suicide
Interventions: BEHAVIORAL: Standard inpatient psychiatric care|BEHAVIORAL: Inpatient Skills Training|BEHAVIORAL: mHealth-supported Skills Training for Alcohol-Related Suicidality (mSTARS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GOAL-Directed ANalgesia (GOALDAN)
Status: UNKNOWN
Conditions: Immediate Severe Postoperative Pain|Perioperative Hemodynamic
Interventions: DRUG: Anesthesic agent guided by ANI (Interventional Group)|DRUG: Administration of the lowest effective concentration of desflurane (Interventional Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of BLB-201 RSV Vaccine in Infants and Children
Status: RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: PIV5-vectored RSV Vaccine (BLB-201) Low Dose|BIOLOGICAL: PIV5-vectored RSV Vaccine (BLB-201) High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness And Safety Of Oral Anticoagulants Among Obese Patients With Non-Valvular A-Fib In VA Patients With Medicare
Status: COMPLETED
Conditions: Atrial Fibrillation|Obesity|Anticoagulants
Interventions: DRUG: Apixaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioral Economic Interventions at Food Pantries
Status: UNKNOWN
Conditions: Food Selection
Interventions: BEHAVIORAL: Order|BEHAVIORAL: Packaging|BEHAVIORAL: Pricing|BEHAVIORAL: Relative Proportions|BEHAVIORAL: Default Option
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Embryonal Childhood Rhabdomyosarcoma|Embryonal-botryoid Childhood Rhabdomyosarcoma|Previously Untreated Childhood Rhabdomyosarcoma
Interventions: PROCEDURE: conventional surgery|DRUG: dactinomycin|DRUG: cyclophosphamide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Posttraumatic Stress Disorder (PTSD) in Adult Survivors of Early Chronic Interpersonal Trauma
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: STAIR|BEHAVIORAL: MPE|BEHAVIORAL: EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veloxis de Novo Kidney Transplant ECSWD
Status: UNKNOWN
Conditions: Kidney Transplantation|Immunosuppression
Interventions: DRUG: Tacrolimus Extended Release Oral Tablet [Envarsus]|DRUG: Mycophenolate Mofetil|DRUG: Mycophenolic Acid Oral Product|DRUG: Tacrolimus|DRUG: Methylprednisolone|DRUG: Prednisone|DRUG: Rabbit Anti-Human T-Lymphocyte Globulin Injectable Solution [Thymoglobulin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Adalimumab|BIOLOGICAL: Adalimumab|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fresh Vs Frozen Surgical Sperm in IVF
Status: TERMINATED
Conditions: Infertility
Interventions: OTHER: Slow Freezing and Thawing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Wild-Type Reovirus, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Wild-type Reovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Salmeterol/Fluticasone Easyhaler and Seretide Diskus (SAIMI)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: salmeterol-fluticasone|DRUG: salmeterol-fluticasone|DRUG: salmeterol-fluticasone|DRUG: salmeterol-fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Local Vibration Applied to Different Regions and Spinal Stabilization Exercises
Status: RECRUITING
Conditions: Multiple Sclerosis|Ataxia
Interventions: DEVICE: paraspinal vibration|DEVICE: gastrosoleus muscle complex vibration|OTHER: Control Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)
Status: COMPLETED
Conditions: Coronary Heart Disease|Stable Angina Pectoris|Unstable Angina Pectoris|Silent Myocardial Ischemia
Interventions: DEVICE: BuMA stent|DEVICE: EXCEL stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Endoscopic Ultrasound Guided Coeliac Plexus Neurolysis for Cancer Pain
Status: NOT_YET_RECRUITING
Conditions: Malignancy|Pain Management
Interventions: DRUG: Alcohol injection|DEVICE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implantitis Surgical Regenerative Therapy Using Bovine Bone Substitute With Hyaluronic Acid
Status: UNKNOWN
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Surgery 1 (Test group)|PROCEDURE: Surgery 2 (Control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ranibizumab Injection in Subjects With Clinically Significant Macular Edema (ME) With Center Involvement Secondary to Diabetes Mellitus (RIDE)
Status: COMPLETED
Conditions: Diabetes Mellitus|Macular Edema
Interventions: DRUG: Ranibizumab|DRUG: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Different Forms of Creatine
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate|DIETARY_SUPPLEMENT: Creatine nitrate-1|DIETARY_SUPPLEMENT: Creatine nitrate-2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of Thymalfasin in Adult Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Thymalfasin (thymosin alpha-1)|PROCEDURE: Trans arterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-Time Monitoring of Circulating Tumor DNA and Study of Prognostic Factors in Patients Treated With CAR-T Cells
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: OTHER: CAR-T cells monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Dexmedetomidine on the Post-Operative Cognition Dysfunction(POCD) in Geriatric Patients
Status: COMPLETED
Conditions: Postoperative Confusion|Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasonography (EUS) Guided Fine Needle Aspiration Using Free Stylet 22g and 25 g Needles
Status: COMPLETED
Conditions: Solid Neoplasms
Interventions: DEVICE: Endosonography guided fine needle aspiration cytology ( Cook Medical, Boston Scientific)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: 3-Dimensional Conformal Radiation Therapy in Treating Patients With Bladder Cancer Who Have Undergone Transurethral Resection of the Bladder
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: diagnostic cystoscopy|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: implanted fiducial-based imaging|PROCEDURE: quality-of-life assessment|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: image-guided radiation therapy|RADIATION: selective external radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Dimethyl Fumarate Related GI Symptom Mitigation
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Simethicone|DRUG: Loperamide|OTHER: Peanut Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Tolerability and Safety of Favipiravir Compared to Ribavirin for the Treatment of Lassa Fever
Status: COMPLETED
Conditions: Lassa Fever
Interventions: DRUG: Ribavirin iv|DRUG: Favipiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Single-Dose Methotrexate Protocol With Letrozole + Single-Dose Methotrexate in the Medical Treatment of Patients Diagnosed With Ectopic Pregnancy
Status: COMPLETED
Conditions: Ectopic Pregnancy
Interventions: DRUG: Letrozole|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: BXCL701|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment
Status: UNKNOWN
Conditions: Encephalitis|Meningitis|Meningoencephalitis|Next-Generation Sequencing|Polymerase Chain Reaction
Interventions: DIAGNOSTIC_TEST: Types of etiological diagnostic methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Venous Thromboembolism Prevention in High-Risk Trauma Patients
Status: COMPLETED
Conditions: Traumatic Injury|Venous Thromboembolism
Interventions: DRUG: Enoxaparin 40 mg q12h|DRUG: Enoxaparin 30 mg q8h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Jeju Steaming Onion(Oniro) on Reducing Body Fat of Overweight or Obesity Subjects
Status: COMPLETED
Conditions: Overweight|Diabetes Mellitus|Obesity
Interventions: DIETARY_SUPPLEMENT: baked barley powder|DIETARY_SUPPLEMENT: jeju steam onion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vital Root-resective Therapy in Furcation-involved Maxillary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontitis|Furcation Defects
Interventions: PROCEDURE: Vital root resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Circulating Tumor Cell|Chemotherapy Effect
Interventions: PROCEDURE: Colorectal cancer resection combined with liver metastasis resection.|DRUG: FOLFOX chemotherapy regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin to Improve Results in Epicanthoplasty
Status: UNKNOWN
Conditions: Scar|Intercanthal Distance Ratio
Interventions: DRUG: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Apatinib Combined With Paclitaxel and Carbopatin Intensive Regimen in Neoadjuvant Therapy for Locally Advanced Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Apatinib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Niclosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sweat Gland Function in Patients With Failed Back Surgery Syndrome, Treated With Spinal Cord Stimulation
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: SCS is switched off|DEVICE: SCS is switched on
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Colorectal Cancer Screening Using Stool DNA-based SDC2 and SFRP2 Methylation Test in China
Status: UNKNOWN
Conditions: Colorectal Neoplasm|Colorectal Cancer|Adenomatous Polyps|Adenoma|Advanced Adenoma|Serrated Polyp
Interventions: DIAGNOSTIC_TEST: Stool-based SDC2 and SFRP2 DNA methylation test|DIAGNOSTIC_TEST: FIT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Staccato Alprazolam|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reandron in Diabetic Men Witn Low Testosterone Level
Status: COMPLETED
Conditions: Type 2 Diabetes|Hypogonadism
Interventions: DRUG: Reandron 1000|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-0120 Safety and PK/PD, Food Effect Study in Healthy Volunteers
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: D-0120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Ceftriaxone and Metronidazole Versus Multiple Doses for Antibiotic Prophylaxis at Elective Cesarean Section.
Status: COMPLETED
Conditions: Post Operative Infections
Interventions: DRUG: Single dose antibiotic|DRUG: Multiple dose antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety of Intraperitoneal Laparoscopic Radical Prostatectomy With or Without Drainage Tube
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Intraperitoneal Laparoscopic Radical Prostatectomy Without Drainage Tube|BEHAVIORAL: Intraperitoneal Laparoscopic Radical Prostatectomy With Drainage Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Lifestyle and Neonatal Hypoglycemia
Status: COMPLETED
Conditions: Hyperinsulinemia|Miscarriages|Pregnancy|Sedentary Lifestyle|Hypoglycemia
Interventions: BEHAVIORAL: Daily brisk walking plus a carbohydrate-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Cocaine Addiction Using mGluR5 PET and fMRI
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: BEHAVIORAL: Psychiatric and Cognitive Testing|DRUG: Cocaine Self-adminstration|RADIATION: Positron Emission Tomography|OTHER: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acute Kidney Outreach to Reduce Deterioration and Death (AKORDD)
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: OTHER: Rapid diagnosis of AKI cause|OTHER: Rapid treatment of AKI cause|OTHER: Stopping 'nephrotoxic' drugs|OTHER: Early nephrology followup for stage 3 AKI|OTHER: Preventing recurrent AKI|OTHER: Good standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Weight-based Enoxaparin Dosing in Obese Medical Patients at Risk for DVT
Status: COMPLETED
Conditions: Obesity|Venous Thrombosis|Anticoagulants
Interventions: DRUG: Enoxaparin 0.5 mg/kg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: QIV|BIOLOGICAL: Matching Placebo for V114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Balance Study Balancing Life and Reducing Stress For Those Providing Elder Care
Status: COMPLETED
Conditions: Dementia|Caregivers|Stress
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|BEHAVIORAL: Caregiver Education & Social Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Vitamin D Supplementation in Cape Town Primary Schoolchildren
Status: COMPLETED
Conditions: Latent Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dutogliptin in Co-administration With Filgrastim in Early Recovery Post-myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Dutogliptin + Filgrastim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Antibiotic Treatment of Group A Streptococcal Blistering Distal Dactylitis in Children
Status: COMPLETED
Conditions: Blistering Distal Dactylitis
Interventions: PROCEDURE: Positive rapid GAS test|PROCEDURE: Negative rapid GAS test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate the Effect of pH on Pain Upon Local Anesthetic Administration.
Status: TERMINATED
Conditions: Local Anesthetics
Interventions: DRUG: Lidocaine|DRUG: normal saline|DRUG: alkalinized lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ALLiance for sEcondary PREvention After an Episode of Acute Coronary Syndrome (ALLEPRE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Nurse-led Intensive Secondary Prevention Programme|BEHAVIORAL: Usual Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Central Obesity on the Esophageal Epithelial Barrier
Status: COMPLETED
Conditions: Gastroesophageal Reflux|GERD
Interventions: PROCEDURE: Confocal endomicroscopy|PROCEDURE: Mucosal impedance|PROCEDURE: Research biopsies|PROCEDURE: Bravo ambulatory pH monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single Dose Randomized Five-Way Crossover Pharmacokinetics (PK) Study of Tadalafil Semi-Chewable (Gummy) Formulations in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction
Interventions: DRUG: Tadalafil 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Gemcitabine With Fish Oil in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Lipidem fish oil infusion + Gemcitabine chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Support Provided to Mothers Through WhatsApp Messaging Application
Status: COMPLETED
Conditions: Exclusive Breastfeeding|Breastfeeding Support
Interventions: OTHER: Breastfeeding Support Provided to Mothers Through WhatsApp Messaging Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vinorelbine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Treatment and Liver Dysfunction
Status: COMPLETED
Conditions: Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: indocyanine green|DRUG: lidocaine|DRUG: vinorelbine ditartrate|OTHER: high performance liquid chromatography|OTHER: intracellular fluorescence polarization analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: LY2189265|DRUG: Metformin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Program Among University Student to Promote Physical Activity and Reduce the Sedentary Time
Status: COMPLETED
Conditions: Physical Activity|Sedentary Behavior|Young Adults|Student
Interventions: BEHAVIORAL: University-based intervention to promote PA and reduce ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: S0200 Carboplatin With or Without Doxil in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 and Social Isolation and Loneliness Trial
Status: UNKNOWN
Conditions: Social Isolation|Loneliness|Geriatric
Interventions: OTHER: HOW R U? Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Prostatic Neoplasm|Colorectal Neoplasms|Endometrial Neoplasms|Hodgkin Disease|Non Hodgkin Lymphoma
Interventions: OTHER: AH-HA Tool in the EPIC EHR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Time Restricted Eating As Treatment (TREAT) for Diabetes Mellitus: A Pre-Post 12 Week Study on the Effectiveness of Intermittent Fasting in Asians With Type 2 Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Time Restricted Eating As Treatment (TREAT) for Diabetes.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Post Abdominal Laparoscopy Prevention With Arcoxia
Status: COMPLETED
Conditions: Laparoscopic Surgery for Appendicitis|Laparoscopic Surgery for Cholecystitis|Laparoscopic Surgery for Ovarian Cysts
Interventions: DRUG: etoricoxib 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bacteria in the Mouth and Throat of Healthy Adults Before and After the Administration of Either Levofloxacin or Azithromycin, Both Antibiotic Medications
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Levofloxacin; Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbapenem-resistant Organisms (CRO) Screening From Rectal Swabs in Patients With Hematological Diseases in China
Status: UNKNOWN
Conditions: Hematological Diseases|Carbapenem-resistant Enterobacteriaceae|Carbapenem-resistant Pseudomonas Aeruginosa|Carbapenem-resistant Acinetobacter Baumannii
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Direct Current Stimulation in Autistic Spectrum Disorder
Status: COMPLETED
Conditions: Autistic Disorders Spectrum
Interventions: DEVICE: DLPFC-R (F4) TDCS|DEVICE: DLPFC-L (F3) and DLPFC-R (F4) TDCS|DEVICE: sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Energy Deficiency in Sport and Dance
Status: NOT_YET_RECRUITING
Conditions: Relative Energy Deficiency in Sport|Bone Stress Reaction
Interventions: RADIATION: Dual x-ray scan|DIAGNOSTIC_TEST: Blood screen|OTHER: Questionnaires|OTHER: Anthropometric measurements|PROCEDURE: Resting Metabolic rate|OTHER: Energy expenditure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Therapeutic Effects of Barkley's Parenting Management Program for Taiwanese School-Aged Children With Attention Deficit/Hyperactivity Disorder (ADHD)
Status: UNKNOWN
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: Barkley's parenting management program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans Fatty Acids and Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: vaccenic acid enriched milk fat (VAMF) [Transfact1]|DIETARY_SUPPLEMENT: hydrogenated oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Interstitial Cystitis: Examination of the Central Autonomic Network
Status: COMPLETED
Conditions: Interstitial Cystitis/Painful Bladder Syndrome|Myofascial Pelvic Pain
Interventions: DRUG: Metoprolol Tartrate Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of a Propolis-based Denture Cleanser
Status: COMPLETED
Conditions: Dental Plaque|Denture Stomatitis|Oral Candidiasis|Oral Hygiene
Interventions: DRUG: Denture soaking solution|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antihypertensive Effect and Safety of Peptides Derived From Coldwater Shrimp
Status: COMPLETED
Conditions: Hypertension|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Marealis Refined Peptide Concentrate|DIETARY_SUPPLEMENT: Marealis Refined Peptide Concentrate|DIETARY_SUPPLEMENT: Marealis Refined Peptide Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training as a Supplemental Therapy of Androgen Deficiency of the Aging Male
Status: COMPLETED
Conditions: Hypogonadism, Male|Physical Activity|Testosterone Deficiency
Interventions: PROCEDURE: Strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biodiesel Exhaust, Acute Vascular and Endothelial Responses
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Forearm venous occlusion plethysmography study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Knee Osteoarthritis|Osteoarthritis Knees Both|Osteoarthritis Knee Left|Osteoarthritis Knee Right|Knee Pain Chronic|Knee Disease|Arthropathy of Knee Joint
Interventions: DEVICE: MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting)|DEVICE: Stryker Triathlon Tritanium Knee System (Condylar Stabilizing)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactated Ringer's Versus 5% Human Albumin: Cardiac Surgical Patients
Status: TERMINATED
Conditions: Hemodynamic Stability
Interventions: DRUG: Lactated Ringer's|DRUG: 5% Human Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Efficacy of FID 112903 Post Discontinuation of Long-term Use of RESTASIS® (Cyclosporine Ophthalmic Emulsion) 0.05%
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: OTHER: FID 112903 (SYSTANE® ULTRA Lubricant Eye Drops)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELAXaHEAD for Headache Patients (Phase II)
Status: COMPLETED
Conditions: Migraine|Headache|Multiple Sclerosis|Insomnia
Interventions: BEHAVIORAL: Smartphone-Based Progressive Muscle Relaxation Therapy (PMR)|BEHAVIORAL: Monitored Usual Care (MUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proportional Assisted Ventilation and Pressure Support Ventilation in Adult Patients With Prolonged Ventilation
Status: COMPLETED
Conditions: Respiratory Failure|Respiration, Artificial
Interventions: DEVICE: PAV+ mode|DEVICE: PSV mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Functional Results of ADM X3-MoP Cup (Stryker) and a CoC Cup (Zimmer) in Young Patients
Status: ENROLLING_BY_INVITATION
Conditions: Arthroplasties, Hip Replacement
Interventions: DEVICE: ADM X3-MoP Cup|DEVICE: CoC Cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Irreversible Electroporation (IRE) for Central Colorectal Liver Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastases
Interventions: PROCEDURE: Irreversible electroporation (IRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LUXSOL(TM) Topical Cream for the Treatment of Symptomatic Bacterial Vaginosis; A Proof of Concept Study
Status: TERMINATED
Conditions: Bacterial Vaginosis (BV)
Interventions: DRUG: LUXSOL copper containing cream|DRUG: Metronidazole gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT)
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction|Subclinical Carotid Atherosclerosis
Interventions: DRUG: Rosuvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of TECAR in Treatment of Rectus Diastasis
Status: COMPLETED
Conditions: Rectus Diastasis
Interventions: OTHER: TECAR application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd
Status: UNKNOWN
Conditions: Omental Patch|Laparoscopic Pancreaticoduodenectomy|Pancreatic Fistula
Interventions: OTHER: omental patchwork
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response
Status: UNKNOWN
Conditions: Glucose Intolerance|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Fruit bar with addition of polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug-Drug Interaction Between Bisoprolol and Ivabradine in Healthy Volunteers
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Bisoprolol|DRUG: Ivabradine|DRUG: combination of Ivabradine and bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lapatinib and Cetuximab in Patients With Solid Tumors
Status: COMPLETED
Conditions: Colorectal Cancer|Lung Cancer|Head and Neck Cancer
Interventions: DRUG: cetuximab and lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Cannula Oxygen Therapy With or Without NIV During the Weaning Period
Status: COMPLETED
Conditions: Acute Respiratory Failure Requiring Reintubation
Interventions: DEVICE: HFNC|DEVICE: NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Radial Pharmaco-invasive Strategy In ST Elevation Myocardial Infarction Trial
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: PROCEDURE: Cardiac catheterization standard strategy|PROCEDURE: Cardiac catheterization fast strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumor|Carcinoid Tumor|Pancreatic Neuroendocrine Tumor
Interventions: DRUG: Sorafenib|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial to Evaluate the Efficacy and Safety of OCV-501 in Elderly Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: OCV-501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplementary Dietary Protein (21g Per Day) on Lean Mass and Strength in Sedentary, Adult Vegetarians
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: mung bean protein|OTHER: control biscuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Community-Based Health Education Programs for the Early Detection of, and Vaccination Against, COVID-19 and the Adoption of Self-Protective Measures of Hong Kong Residents
Status: RECRUITING
Conditions: COVID-19
Interventions: BEHAVIORAL: Community-based Health Education based on core intervention package|BEHAVIORAL: Health Information Sharing Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Near-Infrared Laser Stimulation for Various Neurological Conditions
Status: ENROLLING_BY_INVITATION
Conditions: Refractory Depression|Anxiety Disorders|Neurodegenerative Diseases|Traumatic Brain Injury|Chronic Traumatic Encephalopathy
Interventions: DEVICE: Near Infrared Laser Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIND: Care Coordination for Community-living Person With Dementia
Status: COMPLETED
Conditions: Dementia|Caregiver Burden
Interventions: BEHAVIORAL: MIND-S Intervention|OTHER: Augmented Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diet Induced Ketosis for Patients With Posttraumatic Stress Disorder (PTSD), a Feasibility Study
Status: COMPLETED
Conditions: PTSD|Post Traumatic Stress Disorder
Interventions: OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Curcumin's Effect on Inflammation in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Complication|Hemodialysis-Induced Symptom
Interventions: DRUG: Curcumin Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Psychosocial Nursing Interventions on Sleep, Anxiety and Delirium in Patients Undergoing Open Heart Surgery
Status: RECRUITING
Conditions: Delirium
Interventions: OTHER: Psychosocial nursing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI)
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DRUG: Lexapro|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Crossover Study of Neurally Adjusted Ventilatory Assist (NAVA) in Preterm Infants
Status: COMPLETED
Conditions: Infant, Preterm
Interventions: PROCEDURE: neurally adjusted ventilatory assist (NAVA) ventilator mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria
Status: TERMINATED
Conditions: Dent's Disease|Nephrolithiasis
Interventions: DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Dosage of Acetazolamide for OSA Treatment
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Acetazolamide|DRUG: Acetazolamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A New Study Evaluating the Activity of Modular CAR T for mYeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BCMA CAR T cells|BIOLOGICAL: BCMA/CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study With Midazolam for Sedation in Flexible Bronchoscopy
Status: COMPLETED
Conditions: Sedation|Tolerance|Anxiety|Satisfaction
Interventions: DRUG: Midazolam|OTHER: Physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Electrical Stimulation and Expression of VEGF and NO in Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Electrical Stimulation (BTL-5000 series, United Kingdom)|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT