pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumor|Medulloblastoma|Pineoblastoma
Interventions: RADIATION: proton beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustiva Levels With Use of a Gel Capsule
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Over-encapsulated efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: GDC-0134|DRUG: Placebo|DRUG: Rabeprazole|DRUG: Midazolam|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SSG XXV: The Stop-GIST Trial; Discontinuation of Imatinib in Patients With Oligo-metastatic GIST
Status: SUSPENDED
Conditions: Gastrointestinal Stromal Tumor
Interventions: OTHER: Discontinuation of imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SystemIc iNflammation and Microvascular diSease PreventIon in psoRiatic diseasE
Status: WITHDRAWN
Conditions: Psoriasis|Psoriatic Arthritis|Cardiovascular Risk Factor
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents Pulmonary MDR-TB
Status: RECRUITING
Conditions: Multidrug-Resistant Tuberculosis
Interventions: DRUG: Bedaquiline (TMC207)|DRUG: Background Regimen (BR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Post Cytotoxic Therapy|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Bortezomib|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Postbiotic Product on Colonic Barriers in IBS
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: ReFerm(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma|Carcinoma, Squamous Cell of Head and Neck|Stomach Neoplasms|Triple Negative Breast Neoplasms|Ovarian Neoplasms|Fallopian Tube Neoplasms|Peritoneal Neoplasms|Esophagogastric Junction Neoplasms|Carcinoma, Pancreatic Ductal|Esophageal Squamous Cell Carcinoma
Interventions: DRUG: paclitaxel + carboplatin|DRUG: carboplatin + etoposide|DRUG: gemcitabine + carboplatin|DRUG: nab-paclitaxel (paclitaxel-albumin) + carboplatin|DRUG: oxaliplatin + 5-fluorouracil (5FU) + leucovorin (calcium folinate/folinic acid)|BIOLOGICAL: durvalumab|BIOLOGICAL: tremelimumab|DRUG: nab-paclitaxel (paclitaxel-albumin) + gemcitabine|DRUG: cisplatin + 5-fluorouracil (5FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lnfluence of the Prosthetic Emergence Profile on the Prevalence of Peri-implant Diseases: a Cross Sectional Study
Status: RECRUITING
Conditions: Peri-Implantitis|Peri-implant Health|Peri-implant Mucositis
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Ravidasvir in Combination With Danoprevir/r and Ribavirin(RBV) in Treatment-naive, Non-cirrhotic, Chronic Hepatitis C Virus Genotype1 Infected Subjects.
Status: COMPLETED
Conditions: HCV
Interventions: DRUG: Ravidasvir|DRUG: Danoprevir|DRUG: Ritonavir|DRUG: Ribavirin 100 MG|DRUG: Ravidasvir Placebo|DRUG: Danoprevir Placebo|DRUG: Ritonavir Placebo|DRUG: Ribavirin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Killer(NK) Cell Therapy in r/r AML
Status: RECRUITING
Conditions: AML, Adult
Interventions: DRUG: QN-030a|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix?
Status: COMPLETED
Conditions: Labor; Forced or Induced, Affecting Fetus or Newborn
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effectiveness of StaphVAX in Adults on Hemodialysis
Status: COMPLETED
Conditions: Staphylococcal Infections|Kidney Failure, Chronic
Interventions: BIOLOGICAL: S. aureus Type 5 and 8 Capsular Polysaccharide Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: health literacy appropriate education and demonstration|BEHAVIORAL: shared decision making|BEHAVIORAL: automated call reminders or automated texts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison the Effects of TECAR With Dry Needling in the Treatment of Myofascial Trigger Points
Status: COMPLETED
Conditions: Myofascial Pain Syndrome of Neck|Myofascial Trigger Point Syndrome|Myofascial Trigger Point Pain
Interventions: OTHER: TECAR|OTHER: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of 3D Surface Imaging in the Objective Assessment of Breast Conserving Therapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: 3D surface imaging using a non portable and portable camera|OTHER: Patient reported outcome measure (PROM): BREAST-Q|OTHER: 2D photography|OTHER: Applanation Tonometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Adaptive Trial to Find the Safest And Shortest TB Preventive Regimens.
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis Infection, Latent
Interventions: DRUG: rifampin standard arm|DRUG: rifampin double dose|DRUG: levofloxacin and rifapentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EXPAREL for Minimally Invasive Supracervical Hysterectomies
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Saline Solution for Injection|DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NC Young Women's CoOp
Status: TERMINATED
Conditions: Condomless Sex|Human Immunodeficiency Virus (HIV)|Sexually Transmitted Infection (STI)|Alcohol and Drug Use
Interventions: BEHAVIORAL: Face-to-Face Young Women's CoOp (YWC)|BEHAVIORAL: mHealth Young Women's CoOp (YWC)|BEHAVIORAL: HIV Counseling and Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Structured Multidisciplinary Intervention or Standard Medical Care in Improving Quality of Life in Patients Receiving Active Cancer Treatment
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: PROCEDURE: quality-of-life assessment|BEHAVIORAL: telephone-based intervention|OTHER: questionnaire administration|OTHER: counseling intervention|BEHAVIORAL: exercise intervention|OTHER: educational intervention|BEHAVIORAL: telephone-based intervention|PROCEDURE: standard follow-up care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HPV Vaccination in HIV Infected and HIV Uninfected Adolescents in Eswatini
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Infection|Hiv|HPV Vaccine
Interventions: BIOLOGICAL: Gardasil ® 9
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Guided Internet Delivered Cognitive-Behaviour Therapy for Persons With Spinal Cord Injury: A Feasibility Trial
Status: COMPLETED
Conditions: Spinal Cord Injuries|Depression|Anxiety
Interventions: BEHAVIORAL: Guided ICBT for persons with Spinal Cord Injury|OTHER: Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Diabetic Retinopathy
Interventions: PROCEDURE: Light will be switched from 0.5µW/cm2/sr to 115µW/cm2/sr.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Root Coverage in Miller Class III Recessions by Perio-ortho Treatment
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Periodontal plastic surgery procedure and orthodontic treatment|PROCEDURE: Periodontal plastic surgery procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Antidepressant Discontinuation in Treatment Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression
Interventions: OTHER: Discontinuation of serotonergic antidepressants|OTHER: Continuation of serotonergic medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACT for Methamphetamine Use Disorder in Women and Gender Non-Conforming Individuals
Status: NOT_YET_RECRUITING
Conditions: Methamphetamine Abuse|Methamphetamine-dependence
Interventions: BEHAVIORAL: Acceptance Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Safety and Efficacy of Various Dosage Schedules for Dietressa Drug in Treatment of Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Dietressa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetics of Warfarin When Coadministered With PEX168 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PEX168|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Perioperative Low Dose Ketamine on Postoperative Recovery in Patients Undergoing Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: ketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sustained Treatment-free Remission in BCR-ABL+ Chronic Myeloid Leukemia
Status: UNKNOWN
Conditions: Chronyc Myeloid Leukemia
Interventions: DRUG: Imatinib|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Balanced Crystalloids and Normal Saline in Septic Patients
Status: UNKNOWN
Conditions: Sepsis|Acute Kidney Injury|Septic Shock|Sepsis, Severe
Interventions: DRUG: 0.9% saline|DRUG: lactated Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Hematologic Cancer
Status: WITHDRAWN
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD
Status: TERMINATED
Conditions: PTSD
Interventions: DRUG: SRX246|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of Translatoric Grades of Movement in Hip Osteoarthritis Patients
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: OTHER: Grade I-II SZ mobilization|OTHER: Grade II TZ mobilization|OTHER: Grade III mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imexon for Relapsed Follicular and Aggressive Lymphomas
Status: COMPLETED
Conditions: Follicular Lymphoma|Small Lymphocytic Lymphoma|Marginal Zone Lymphoma|Lymphoplasmacytic Lymphoma|Diffuse Large B Cell Lymphoma|Mantle Cell Lymphoma|Burkitt's Lymphoma
Interventions: DRUG: Imexon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diluent Volume on Colistin Inhalation Therapy
Status: RECRUITING
Conditions: Inhalation Pneumonia
Interventions: OTHER: Colistin 1 MU in normal saline 1 ml|OTHER: Colistin 1 MU in normal saline 2 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Detection of Circulating Tumor Tells as The Guidance of the Neoadjuvant Chemotherapy of Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer TNM Staging Primary Tumor (T) T3
Interventions: PROCEDURE: chemotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Examining Community-based Effectiveness of a Substance Use and HIV Risk Reduction Intervention for Young Men of Color
Status: COMPLETED
Conditions: Substance Use|Sexual Risk
Interventions: BEHAVIORAL: YMHP Intervention|BEHAVIORAL: Enhanced Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Medical Therapy of Prostatic Symptoms
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Prostatic Hypertrophy, Benign
Interventions: DRUG: Doxazosin|DRUG: Finasteride|DRUG: Doxazosin placebo|DRUG: Finasteride placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Vinorelbine Plus Cisplatin (NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESP vs STB for Pain and Diagraphragm Function for Shoulder Surgery
Status: RECRUITING
Conditions: Rotator Cuff Injuries
Interventions: PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivness and Safety of Acupuncture Combined With Moxibustion for Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: OTHER: acupuncture combined moxibustion|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults
Status: COMPLETED
Conditions: Inguinal Hernia, Indirect|Surgery|Postoperative Pain|Recurrence
Interventions: PROCEDURE: Modified percutaneous internal ring suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ITA Model of Integrated Treatment of Eating Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Eating Disorders|Anorexia Nervosa|Bulimia Nervosa|Binge Eating|Eating Disorders in Adolescence|Eating and Feeding Disorders
Interventions: OTHER: ITA Integrated Treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treat and Extend Therapy Study Using Intravitreal Aflibercept for Patients Exited From Protocol VGFT-OD 0910
Status: UNKNOWN
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Zapperclick Device for Relief From Mosquito Bites
Status: UNKNOWN
Conditions: Insect Bites|Stings
Interventions: DEVICE: Zapperclick|DEVICE: Inactivated zapperclick device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent Preferences and Family Engagement in a Conduct Problems Prevention Program
Status: COMPLETED
Conditions: Conduct Problems
Interventions: BEHAVIORAL: PMTO-PTC Group clinic-based|BEHAVIORAL: PMTO Individual home-based|BEHAVIORAL: PMTO Individual clinic-based|BEHAVIORAL: Services as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of AV Optimization Methods Used in Cardiac Resynchronization Therapy (CRT)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: AV Delay programming through cardiac resynchronization therapy|DEVICE: AV Delay programming through cardiac resynchronization therapy|DEVICE: AV Delay programming through cardiac resynchronization therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of (Sub)Clinical Toxicity in Irradiated vs. Non-irradiated Surgically Treated Esophageal Cancer Patients: a Pilot Study (CROSS SECT)
Status: COMPLETED
Conditions: Thoracic Tumor
Interventions: DIAGNOSTIC_TEST: CTTC scan, cardiac MRI, ECG, 6 minute walking test, echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Zolpidem Tartrate Tablets and Ambien® Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zolpidem Tartrate 10 mg tablet|DRUG: Zolpidem Tartrate 10 mg tablet (Ambien®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Three Different Approaches for Ultrasound Guided Femoral Nerve Block for Patients Undergoing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Femoral nerve block|PROCEDURE: Femoral nerve block non stimulating catheter|PROCEDURE: Femoral nerve block stimulating catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of OPB-111077 in Patients With Relapsed or Refractory Acute Myeloid Leukaemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: OPB-111077
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone (BMT CTN 1705)
Status: ACTIVE_NOT_RECRUITING
Conditions: Graft Versus Host Disease (GVHD)
Interventions: BIOLOGICAL: Alpha-1 antitrypsin (AAT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis
Status: RECRUITING
Conditions: Post Menopausal Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Mother-of-pearl|DIETARY_SUPPLEMENT: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Precision Medicine With Zibotentan in Microvascular Angina
Status: COMPLETED
Conditions: Microvascular Angina
Interventions: DRUG: Zibotentan|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19
Status: WITHDRAWN
Conditions: covid19
Interventions: DRUG: Nitazoxanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
Status: COMPLETED
Conditions: Kidney Stones
Interventions: DEVICE: Laser|DEVICE: Ultrasonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Effect of Neuromuscular Electro-stimulation on the Performance of Isometric Rotator Cuff Strength.
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Impingement Syndrome|Rotator Cuff Tendinitis|Subacromial Impingement Syndrome
Interventions: OTHER: STRENGTH EVALUATION WITH ELECTROSTIMULATOR|OTHER: STRENGTH EVALUATION WITHOUT ELECTROSTIMULATOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Status: COMPLETED
Conditions: Nicotine Dependence|Major Depressive Disorder
Interventions: DRUG: Varenicline|BEHAVIORAL: BASC|BEHAVIORAL: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intraperitonael Nebulization of Local Anesthetic on Postoperative Pain Associated With Laparoscopic Surgery
Status: COMPLETED
Conditions: Gynecologic Laparoscopic Surgery
Interventions: DRUG: Ropivacaine 30 mg|DRUG: Ropivacaine 30 mg|DRUG: Ropivacaine 100 mg|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV, 9 Weeks Comparison Between MICARDIS 80 mg and Amlodipine 10 mg on Biological PPAR Gamma Activities
Status: COMPLETED
Conditions: Hypertension|Metabolic Syndrome X
Interventions: DRUG: Micardis|DRUG: Amlodipine|PROCEDURE: Abdominal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Micro-abrasive Blasting vs Acid Etching of Orthodontic Bracket Bases
Status: COMPLETED
Conditions: Orthodontic Appliances
Interventions: DEVICE: Acid etched brackets|DEVICE: Sandblasted brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for the Treatment of Ulcerative Colitis With Adacolumn (Companion to US Study 512-04-205)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DEVICE: Adacolumn Apheresis System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction
Status: WITHDRAWN
Conditions: Graves Ophthalmopathy
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Implementation and Impact of Provincial Scale-up of the Adapted Choose to Move (CTM) Program
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Mobility Limitation|Physical Inactivity|Loneliness|Social Isolation
Interventions: BEHAVIORAL: Choose to Move
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Investigate The Effect Of Erythromycin On The Pharmacokinetics Of PH-797804
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PH-797804|DRUG: PH-797804 + erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-Term Safety of Treximet (Sumatriptan/Naproxen Sodium) for Migraine in Adolescents
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Combination Tablet of Treximet (sumatriptan/naproxen sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anesthetic Drugs on Neurocognitive Function in Children With Retinoblastoma Requiring Multiple Anesthetic Exposure - Preliminary Study
Status: RECRUITING
Conditions: Retinoblastoma
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: L-arginine Effects on Chronic Hypertension in Pregnancy
Status: COMPLETED
Conditions: Hypertension in Pregnancy
Interventions: DRUG: L-arginine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: R-CVP for the Treatment of Non-conjunctival Ocular Adnexal MALT Lymphoma (OAML)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: rituximab, cyclophosphamide, vincristine, and prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Hypertension|Obesity|Diabetes|Hyperdiploid|Fatigue Syndrome, Chronic|Insomnia Chronic|Quality of Life|Economic Problems|Compliance, Patient|Health Impairment
Interventions: DEVICE: Auto-CPAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Reality During Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Hemodialysis-Induced Symptom
Interventions: OTHER: Virtual reality exercise during hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab
Status: COMPLETED
Conditions: HER2/Neu Positive|HLA-A2 Positive Cells Present|Stage IV Breast Cancer|Stage IV Ovarian Cancer
Interventions: BIOLOGICAL: HER-2/neu Peptide Vaccine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Family-Based Diabetes Intervention for Hispanic Adults in an Emerging Community
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes self-management program for Hispanics and their families|BEHAVIORAL: General health educational program for Hispanics and their families
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study Protocol of ANAWIDOW Lyophilized Powder for Solution for Intravenous Use in Fasting Conditions
Status: COMPLETED
Conditions: Latrodectism
Interventions: DRUG: ANAWIDOW [antivenin latrodectus (black widow) equine immune F(ab)2] lyophilized powder for solution 10 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver
Status: COMPLETED
Conditions: Fatty Liver
Interventions: DRUG: Polyunsaturated fatty acid (Opti-EPA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Integration Success of an Implant System With a Novel Abutment Attachment Design in Early Loaded Cases
Status: COMPLETED
Conditions: Partial Edentulism|Tooth Disease
Interventions: DEVICE: Implant with new abutment connection|DEVICE: Nanotite Certain Tapered implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sedation by Esketamine and Sevoflurane
Status: UNKNOWN
Conditions: Sevoflurane
Interventions: DRUG: Sevoflurane|DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Multiple-Doses of Erenumab (AMG 334) in Healthy Adults and in Migraine Patients
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Dental Flossing Before or After Tooth Brushing on Interproximal Plaque Reduction and Fluoride Retention in That Area
Status: COMPLETED
Conditions: Dental Devices, Home Care
Interventions: BEHAVIORAL: Flossing before Brushing|BEHAVIORAL: Brushing before Flossing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures
Status: RECRUITING
Conditions: Partial Epilepsy
Interventions: DRUG: Xcopri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Afimetoran|DRUG: Phenytoin|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravitreal Triamcinolone Acetonide in Eyes With Post Vitrectomy Diabetic Vitreous Hemorrhage
Status: UNKNOWN
Conditions: Post Vitrectomy State|Recurrent Diabetic Vitreous Hemorrhage
Interventions: PROCEDURE: Intravitreal triamcinolone injection|PROCEDURE: Air-fluid exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and ABI-007 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: paclitaxel|DRUG: paclitaxel albumin-stabilized nanoparticle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Panitumumab Plus Gemcitabine and Oxaliplatin (GEMOX)Versus GEMOX Alone to Treat Advanced Biliary Tract Adenocarcinoma
Status: COMPLETED
Conditions: Biliary Carcinoma
Interventions: DRUG: Panitumumab plus GEMOX chemotherapy|DRUG: GEMOX chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Biomedics Monthly Sphere and Avaira Vitality Sphere
Status: ACTIVE_NOT_RECRUITING
Conditions: Ametropia
Interventions: DEVICE: Lens A (ocufilcon D)|DEVICE: Lens B (fanfilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Envlo Tablet or Envlomet SR Tablet in Patients With Type II Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Enavogliflozin|DRUG: Enavogliflozin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Buprenorphine Delivered by Buprenorphine Transdermal System (BTDS) at Doses up to 80 Micrograms/Hour (mcg/hr) and Naltrexone on Electrocardiogram (ECG) Intervals in Healthy Volunteers
Status: COMPLETED
Conditions: ECG Effects
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Naltrexone tablet|DRUG: Placebos (for TDS and for naltrexone and for moxifloxacin)|DRUG: Moxifloxacin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SR58611A co-Administered With Escitalopram in Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SR58611A|DRUG: escitalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Satellite-supplementation of Medical Outreach Clinics: a Feasibility Study
Status: COMPLETED
Conditions: Telemedicine|Primary Health Care|Developing Countries|Diagnosis|Therapeutics
Interventions: OTHER: Telemedicine|OTHER: In-person physician interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth
Status: RECRUITING
Conditions: Mood Disturbance|Mood Disorders|Natural Supplements|Alternative Treatment
Interventions: DRUG: Open-label Treatment with Omega-3 Fatty Acids + Inositol|DRUG: Open-label Treatment with N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into the Effects of a Wild Blueberry Powder and a Wild Blueberry Extract on Cognition in Older Adults
Status: COMPLETED
Conditions: Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Wild Blueberry Powder - 450mg|DIETARY_SUPPLEMENT: Wild Blueberry Powder - 900 mg|DIETARY_SUPPLEMENT: Wild Blueberry extract 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy and/or Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: chlorambucil|DRUG: prednisolone|DRUG: procarbazine hydrochloride|DRUG: vinblastine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone Acetate Injection 150 mg/1 mL in Postmenopausal Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: medroxyprogesterone acetate|DRUG: medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessing the Feasibility and Acceptability of a Virtual Food Skills Program for Children With Type 1 Diabetes During COVID-19
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: OTHER: summerlunch+ At Home Food Skills Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Cinacalcet to Treat the Hypophosphatemia of Early Kidney Transplant
Status: TERMINATED
Conditions: Hypophosphatemia|Renal Transplant
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Tamsulosin in Children With Neurogenic Bladder
Status: COMPLETED
Conditions: Bladder, Neurogenic
Interventions: DRUG: tamsulosin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)
Status: WITHDRAWN
Conditions: Hypoxic-Ischemic Encephalopathy|Birth Asphyxia
Interventions: OTHER: Umbilical Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Sm29 in Combination With Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis.
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis, American
Interventions: DRUG: Sm29 Protein, Schistosoma Mansoni|DRUG: Pentavalent antimony (Sbv)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pudendal Blocks on Voiding Dysfunction Following Slings
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Pudendal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety, Tolerability and Immunogenicity Study of SB5 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: SB5|BIOLOGICAL: EU sourced Humira®|BIOLOGICAL: US sourced Humira®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: PMZ-1620 (Sovateltide) in Patients of Acute Spinal Cord Injury
Status: RECRUITING
Conditions: Acute Spinal Cord Injury
Interventions: DRUG: Normal Saline along with standard treatment|DRUG: PMZ-1620 along with standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermatomyositis (DM) or Anti-synthetase Inflammatory Myositis (ASIM)
Status: RECRUITING
Conditions: Idiopathic Inflammatory Myositis
Interventions: DRUG: Daxdilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Hemoglobin Monitoring for Maintaining Hemoglobin Concentration Within the Target Range
Status: COMPLETED
Conditions: Hemoglobins|Blood Transfusion|Hemorrhage
Interventions: PROCEDURE: SpHb monitoring|PROCEDURE: Conventional management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Ascorbate for Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition
Status: UNKNOWN
Conditions: Relapsing-remitting Multiple Sclerosis|Secondary-progressive Multiple Sclerosis|Primary-progressive Multiple Sclerosis
Interventions: DRUG: estriol|OTHER: Placebo|DRUG: Norethindrone|OTHER: Progestin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Positive Pressure Ventilation in Overlap Syndrome
Status: UNKNOWN
Conditions: COPD|Sleep Apnea Syndromes|Non-invasive Positive Pressure Ventilation
Interventions: DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Global Prevalence of ATTR-CM in Participants With HFpEF
Status: TERMINATED
Conditions: Transthyretin Amyloid Cardiomyopathy|Heart Failure With Preserved Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: KJ-TFC-004 Drug-drug Interaction Study
Status: COMPLETED
Conditions: Glaucoma|Eye Diseases|Ocular Hypertension
Interventions: DRUG: [A]|DRUG: [B]|DRUG: [A]+[B](1)|DRUG: [A]+[B](2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bordetella Pertussis Colonisation Challenge Study
Status: UNKNOWN
Conditions: Whooping Cough
Interventions: BIOLOGICAL: Bordetella Pertussis B1917|DRUG: Azithromycin 500 mg|OTHER: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of a Novel Nutritional Product on Nutrient Status and Digestive Health
Status: COMPLETED
Conditions: Gastrointestinal Microbiome|Nutrition, Healthy|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: AG1 - Nutritional Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Whole-body Vibration on Balance Control, Postural Stability and Mobility After Thermal Burn Injuries.
Status: COMPLETED
Conditions: Thermal Burn
Interventions: DEVICE: whole body vibration device|OTHER: routine physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sleeve Gastrectomy With Transit Bipartition(SG+TB) Versus Roux-en-Y Gastric Bypass (RYGB) for Type 3 Obesity
Status: RECRUITING
Conditions: Severe Obesity
Interventions: PROCEDURE: sleeve gastrectomy with transit bipartition (SG +TB)|PROCEDURE: Roux-en-Y gastric bypass (RYGB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Long-term Safety and Efficacy of CDP6038 (Olokizumab) With Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: CDP6038 (olokizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zonisamide Capsules 100 mg|DRUG: Zonegran® Capsules 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Mannitol Versus Polyethylene Glycol Electrolyte Dispersion as a Salve for Patients With Inadequate Bowel Preparation: a Randomized Controlled Clinical Trial
Status: RECRUITING
Conditions: Bowel Cleansing; Good Taste
Interventions: DRUG: Mannitol|DRUG: Polyethylene glycol electrolyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT