pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Extension Study to Assess Persistence of Benefit of LibiGel for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: transdermal testosterone gel 1%|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acu-TENS as an Adjunct Analgesic During USG-MVA
Status: NOT_YET_RECRUITING
Conditions: Pain, Acute
Interventions: DEVICE: Acu-TENS|DEVICE: Sham acu-TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of AK120 in Subjects With Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: AK120|DRUG: AK120|DRUG: Placebo|DRUG: AK120|DRUG: AK120|DRUG: AK120|DRUG: Placebo|DRUG: AK120|DRUG: AK120|DRUG: AK120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without Food
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ritlecitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: rTMS: A Treatment to Restore Function After Severe TBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: rTMS|DEVICE: Placebo rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Melanoma (Skin)|Metastatic Cancer
Interventions: BIOLOGICAL: monoclonal antibody Me1-14 F(ab')2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: RRx-001|DRUG: Regorafenib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PiCCA Study (Panitumumab in Combination With Cisplatin/Gemcitabine)
Status: COMPLETED
Conditions: Cholangiocarcinomas
Interventions: DRUG: Cisplatin, Gemcitabine, Panitumumab|DRUG: Cisplatin, Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: PROCEDURE: Laser Based Photoacoustic Tomography, MRI, Ultrasound|PROCEDURE: laser based photoacoustic tomography, MRI, ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Betamethasone Microsphere in Patients With Diabetic Macular Edema (TSUBASA)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Betamethasone Microsphere (DE-102） Low Dose|DRUG: Betamethasone Microsphere (DE-102） High Dose|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Efficacy and Tolerability of Antistax® in Male and Female Patients Suffering From Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: DRUG: Antistax®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Hyperinsulinism|Polycystic Ovary Syndrome
Interventions: DRUG: clomiphene citrate|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial Magnetic Resonance Imaging Sub-study
Status: TERMINATED
Conditions: Stroke|Cerebral Small Vessel Diseases|Intracerebral Hemorrhage|Vascular Dementia|Hypertension
Interventions: DRUG: telmisartan 20 mg + amlodipine 2.5mg + indapamide 1.25mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy of Multi-waved Locked System Laser Versus Cold Compression Therapy on Breast Cancer-related Lymphoedema
Status: COMPLETED
Conditions: Lymphedema
Interventions: DEVICE: Multi-waved Locked System Laser|DEVICE: Cold Compression therapy|OTHER: complete decongestive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exergaming With Immersive Virtual Reality For People With Multiple Sclerosis (ExeRVIEM)
Status: RECRUITING
Conditions: Multiple Sclerosis|Physical Therapy|Exercise|Virtual Reality Exposure Therapy|Rehabilitation
Interventions: OTHER: ExeRVIEM Program|OTHER: Usual center program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hydroxychloroquine and Phlebotomy for Treating Porphyria Cutanea Tarda
Status: COMPLETED
Conditions: Porphyria Cutanea Tarda
Interventions: DRUG: Hydroxychloroquine|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nepafenac Compared to Placebo for Ocular Pain and Inflammation
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Nepafenac Ophthalmic Suspension, 0.1%|OTHER: Nepafenac Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Cefprozil Granule in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cefprozil 125mg/5ml Susp; Cefprozil granule (125mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Lymph Node Involvement|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Postoperative Delirium|Postoperative Stroke|Postoperative Cognitive Dysfunction
Interventions: OTHER: Preoperative data collection|DIAGNOSTIC_TEST: Intraoperative NIRS|DIAGNOSTIC_TEST: Intraoperative TCD|DIAGNOSTIC_TEST: Intraoperative invasive MAP|DIAGNOSTIC_TEST: Postoperative NIRS|OTHER: Postoperative data collection|DIAGNOSTIC_TEST: Collection of serum biomarker panel|DIAGNOSTIC_TEST: Collection of blood sample for genetic study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobilization With Movement vs. Neural Mobilization on Nerve Root Function in Patients With Cervical Radiculopathy
Status: COMPLETED
Conditions: Disc Herniation|Cervical Radiculopathy|Cervical Radiculopathy at C5 Nerve Root|Cervical Radiculopathy at C6 Nerve Root|Cervical Radiculopathy at C7 Nerve Root
Interventions: OTHER: Sustained natural apophyseal glides (SNAGS)|OTHER: Neural mobilization|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Anatomical Direct Insertion Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: direct insertion anterior cruciate ligament reconstruction|PROCEDURE: single bundle anterior cruciate ligament reconstruction|PROCEDURE: double bundle anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Status: COMPLETED
Conditions: Cognitive/Functional Effects|Metastatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients
Status: TERMINATED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Tibial Nerve Mobilization in Patients With Tarsal Tunnel Syndrome
Status: COMPLETED
Conditions: Nerve Compression Syndromes|Neuropathic Pain
Interventions: OTHER: Tibial Nerve Mobilization|OTHER: Foot-ankle range of motion exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Time to Defibrillation Using Automated External Defibrillators by Pediatric Residents in Simulated Cardiac Arrests
Status: COMPLETED
Conditions: Pediatric Residents
Interventions: DEVICE: Automated external defibrillator|DEVICE: Manual defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Selection Study of Oral Recombinant Salmon Calcitonin (rsCT) in Normal, Healthy, Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Recombinant Salmon Calcitonin (rsCT)|DRUG: Oral Tablet|DRUG: Oral Tablet|DRUG: Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Life Style Patterns and the Development Trend of Chronic Diseases in Healthy and Sub-healthy Groups Were Analyzed by Using Data-mining Techniques
Status: UNKNOWN
Conditions: Chronic Kidney Disease Stage 1|Chronic Kidney Disease Stage 2|Chronic Kidney Disease Stage 3|Chronic Kidney Disease Stage 4|Chronic Kidney Disease Stage 5|Metabolic Syndrome|Chronic Disease
Interventions: OTHER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Evaluation of Metal Ion Release From Metal-on-Metal Cementless Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Avascular Necrosis|Traumatic Arthritis|Rheumatoid Arthritis
Interventions: PROCEDURE: Metal on Metal cementless hip
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides
Status: COMPLETED
Conditions: Neuroblastoma|Ewing's Sarcoma|Wilm's Tumor|Retinoblastoma|Glioma
Interventions: DRUG: racotumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug Study in Healthy Adult Volunteers in a Model of Insomnia (0928-007)
Status: WITHDRAWN
Conditions: Insomnia
Interventions: DRUG: MK0928, gaboxadol / Duration of Treatment: 10 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Radiation Toxicity|Recurrent Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DIETARY_SUPPLEMENT: alkaline water|DIETARY_SUPPLEMENT: distilled water|RADIATION: external beam radiation therapy (EBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Performance and Safety of Eye Drops With Hydroxypropyl-methylcellulose and Inositol in Drye Eye Disease
Status: RECRUITING
Conditions: Dry Eye Disease Associated to Asthenopia and Accommodative Effort in Video Display Terminal Users
Interventions: DEVICE: MERAMIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis|Alcohol Effect|Driving Under the Influence of Alcohol and Other Drugs
Interventions: DRUG: Active inhaled delta-9-THC|DRUG: Placebo|DRUG: Placebo|DRUG: Active Oral Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma
Status: COMPLETED
Conditions: Localized Unresectable Neuroblastoma|Recurrent Neuroblastoma|Regional Neuroblastoma|Stage 4 Neuroblastoma|Stage 4S Neuroblastoma
Interventions: DRUG: Isotretinoin|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Ibritumomab Tiuxetan (Zevalin®) in Combination With a Fludarabine-based Reduced Intensity Conditioning (RIC) Regimen (ZEVALLO 2007)
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Ibritumomab Tiuxetan (Zevalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Positive Psychology and Effects on Well-being of Anaesthesiologists in Hong Kong
Status: RECRUITING
Conditions: Burn Out|Stress, Psychological|Well-Being, Psychological|Self-Compassion|Depressive Symptoms|Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: App-based Positive Psychology Intervention (A&B)|BEHAVIORAL: App-based Positive Psychology Intervention (C&D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia for Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Celebrex, acetaminophen, and dexamethasone|PROCEDURE: Saline irrigation, aspiration of pneumoperitoneum, and low pressure penumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study of How Different Amounts of a New Medicine NNC0148-0287 C (Insulin 287) Works on the Blood Sugar of People Who Are Japanese With Type 1 Diabetes When Given Once a Week
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: insulin icodec|DRUG: Insulin glargine U100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Duration Holter ECG in Fabry Disease
Status: NOT_YET_RECRUITING
Conditions: Fabry Disease
Interventions: DIAGNOSTIC_TEST: Implantation (subcutaneous) of a marketed miniaturized Holter ECG recording device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of Acclimate Feature for Positive Airway Pressure (PAP) Therapy
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: S9 Elite with Acclimate|DEVICE: S9 Elite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Hallucinations by Targeting the rSTS With tES
Status: RECRUITING
Conditions: Hallucinations, Auditory|Psychosis
Interventions: DEVICE: Transcranial Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell Lymphomas
Status: COMPLETED
Conditions: Aggressive Non-Hodgkin Lymphoma
Interventions: DRUG: Prednisone|DRUG: Vinorelbine|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALM-488 for Intra-Operative Visualization of Nerves in Head and Neck Surgery
Status: RECRUITING
Conditions: Surgery
Interventions: DRUG: ALM-488|OTHER: Intraoperative Visualization using White Light Reflectance (WLR) with Fluorescence (FL) Overlay|OTHER: Intra-operative Visualization using White Light Reflectance (WLR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Single-session Endoscopic Stone Extraction
Status: RECRUITING
Conditions: Choledocholithiasis With Acute Cholangitis
Interventions: PROCEDURE: single-session ERCP|PROCEDURE: two-session ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEEK Versus Metallic Attachment-retained Obturators
Status: COMPLETED
Conditions: Maxillary Neoplasms
Interventions: OTHER: PEEK attachment retained obturator|OTHER: metalic attachment retained obturator|OTHER: conventional obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Mosunetuzumab (BTCT4465A) as Consolidation Therapy in Participants With Diffuse Large B-Cell Lymphoma Following First-Line Immunochemotherapy and as Monotherapy or in Combination With Polatuzumab Vedotin in Elderly/Unfit Participants With Previously Untreated Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Mosunetuzumab Intravenous (IV)|DRUG: Mosunetuzumab Subcutaneous (SC)|DRUG: Polatuzumab Vedotin|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study To Investigate the Pharmacokinetics and Pharmacodynamics of Repeat Escalating Doses of the Oral AKT Inhibitor GSK2141795 by 18F FDG PET Analysis in Subjects With Ovarian Cancer
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: GSK2141795
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Focused Electromagnetic Therapy Combined With Foot Core Training for Pronated Foot
Status: NOT_YET_RECRUITING
Conditions: Flexible Flatfoot
Interventions: DEVICE: High-intensity focused electromagnetic therapy|BEHAVIORAL: Foot core training|DEVICE: Sham high-intensity focused electromagnetic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sonographic Measurement of Intraneural Blood Flow in the Median Nerve
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Median Nerve Injury
Interventions: BEHAVIORAL: Cooling|BEHAVIORAL: Heating|BEHAVIORAL: Exercising|BEHAVIORAL: Typing|BEHAVIORAL: Using a mouse|BEHAVIORAL: Cooking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
Status: RECRUITING
Conditions: High Risk Pregnancy|Congenital Heart Disease|Fetal Hydrops|Twin Monochorionic Monoamniotic Placenta|Gastroschisis|Fetal Demise|Stillbirth|Fetal Arrhythmia|Long QT Syndrome|Intrauterine Fetal Death|Sudden Infant Death|Pregnancy Loss|Twin Twin Transfusion Syndrome|Birth Defect|Fetal Cardiac Anomaly|Fetal Cardiac Disorder|Fetal Death|Brugada Syndrome
Interventions: DIAGNOSTIC_TEST: Fetal Magnetocardiogram and Neonatal Electrocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Exemestane After Anastrozole or Letrozole Treatment of Postmenopausal Women With Hormone Responsive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: letrozole|DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence to Guidelines VAccination in Type 1 DIabetes Mellitus Patients (AVADI-1).
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Influenza vaccination|BIOLOGICAL: Pneumococcal vaccination|BIOLOGICAL: Hepatitis B Virus (HBV) vaccination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival
Status: RECRUITING
Conditions: Hypothermia|Delirium|Long-term Survivors|Cancer Surgery
Interventions: OTHER: Routine thermal management|OTHER: Target temperature management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modulating Pain Using Transcranial Alternating Stimulation (tACS) in Healthy Human Subjects
Status: COMPLETED
Conditions: Experimental Pain in Healthy Human Subjects
Interventions: DEVICE: 10 Hz tACS of the bilateral somatosensory cortex|DEVICE: 10 Hz tACS of the prefrontal cortex|DEVICE: 80 Hz tACS of the bilateral somatosensory cortex|DEVICE: 80 Hz tACS of the prefrontal cortex|DEVICE: Sham stimulation of the bilateral somatosensory cortex|DEVICE: Sham stimulation of the prefrontal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DETECT-RPC Universal EM Screening
Status: NOT_YET_RECRUITING
Conditions: Elder Abuse
Interventions: BEHAVIORAL: Detection of Elder mistreatment Through Emergency Care Technicians-Revised for Primary Care (DETECT-RPC) screening tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Feasibility and Safety of Avoiding Chest Tube Placement After Video-assisted Thoracoscopic Surgery (VATS）of the Lung
Status: UNKNOWN
Conditions: Lung Diseases
Interventions: PROCEDURE: avoid chest drainage tube placement after video-assisted thoracoscopic wedge resection of lung|PROCEDURE: Indewlling chest drainage tube after video-assisted thoracoscopic wedge resection of lung
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Pfs230D1M-EPA/AS01|BIOLOGICAL: HAVRIX|BIOLOGICAL: TYPHIM Vi (Salmonella typhi vaccine)|BIOLOGICAL: Menactra|BIOLOGICAL: AVAXIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Analgesic Methods, and Their Effects on Patient Recovery, Following Liver Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Standard optimised recovery protocol.|OTHER: Wound catheter plus patient-controlled analgesia.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bupropion for the Treatment of Apathy in Alzheimer's Dementia
Status: COMPLETED
Conditions: Apathy in Dementia
Interventions: DRUG: Elontril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chronic Disease Self-management Program in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Chronic disease self-management program|OTHER: General psychiatric intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cognitive Exercise on Upper Extremity Functions, Balance and Cognitive Functions in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Cognitive Rehabilitation|OTHER: Core-based Upper Extremity Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds
Status: COMPLETED
Conditions: Oral Soft Tissue Conditions|Drug Effect|Drug Use
Interventions: DRUG: Flurbiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients
Status: COMPLETED
Conditions: Heart Diseases
Interventions: PROCEDURE: Cardiac output measurement at random to respiration|PROCEDURE: Cardiac output measurement synchronised at start of expiration|PROCEDURE: Cardiac output measurement timed to instructed exhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of AK104, a PD-1/CTLA-4 Bispecific Antibody, in Selected Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Melanoma
Interventions: BIOLOGICAL: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Permanence of Indocyanine Green in Axillary Lymph Nodes 3 Weeks After Subdermal Injection in Patients With Breast Cancer and Metastatic Lymph Nodes
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Titanium Mesh Versus Collagen Membrane for Closure of Window in Maxillary Sinus Elevation With Implant Placement
Status: COMPLETED
Conditions: Edentulous; Alveolar Process, Atrophy
Interventions: PROCEDURE: titanium mesh|PROCEDURE: collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison of Surgical Outcomes With Using Integrated Robotic Technology Versus Conventional Laparoscopy for Gastric Cancer Surgery
Status: UNKNOWN
Conditions: Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Interventions: PROCEDURE: Integrated robotic surgery|PROCEDURE: Conventional laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Autologous Dendritic Cells Pulsed With HIV-Antigens for Treatment of Patients With Chronic HIV-Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Peptides on autologous Dendritic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy and Safety of Concomitant Administration of Ciclesonide Nasal Spray and Azelastine Nasal Spray in Patients (18 Years or Older) With Perennial Allergic Rhinitis (PAR) Not Adequately Controlled on an Intranasal Corticosteroid or Antihistamine Monotherapy (BY9010/M1-490)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Ciclesonide nasal spray + placebo Azelastine|DRUG: Ciclesonide nasal spray + Azelastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics Pilot Project
Status: UNKNOWN
Conditions: Staphylococcus Aureus
Interventions: DIETARY_SUPPLEMENT: Bacillus subtilis probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 12wks of Age
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae Vaccines
Interventions: BIOLOGICAL: Synflorix|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Guided Imagery in Children With Type 1 Diabetes Mellitus on Glucose Levels and on Glycemic Control
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: BEHAVIORAL: guided imaginary|BEHAVIORAL: music ONLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zurich Disability Prevention Trial
Status: COMPLETED
Conditions: Community-dwelling Seniors|History of a Fall in the Previous 12 Months
Interventions: DRUG: Hidroferol® (ES)|DIETARY_SUPPLEMENT: ViDe3 (CH)|DIETARY_SUPPLEMENT: ViDe3 (CH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Synergistic Effects of Biofeedback and Transcranial Electrical Stimulation in Anxio-depressive Disorders
Status: COMPLETED
Conditions: Anxiety Depression
Interventions: DEVICE: Transcranial direct current stimulation (t-DCS) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COPD E-cigarette Topography Training
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Tobacco Smoking
Interventions: BEHAVIORAL: Brief advice|BEHAVIORAL: Single Training|BEHAVIORAL: Training to Competency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF
Status: NOT_YET_RECRUITING
Conditions: Endodontic Disease|Periodontitis
Interventions: PROCEDURE: Experimental: RCT using hydraulic calcium silicate sealer and L-PRF + GTR|PROCEDURE: Experimental: RCT using conventional sealer and L-PRF + GTR|PROCEDURE: Experimental: RCT using hydraulic calcium silicate sealer and GTR|PROCEDURE: Active Comparator: RCT using conventional sealer and GTR (bone substitute + collagen membrane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective CD28 Blockade in Renal Transplant Recipients
Status: WITHDRAWN
Conditions: Kidney Transplantation|Renal Transplant Recipients
Interventions: BIOLOGICAL: Lulizumab|DRUG: Tacrolimus|BIOLOGICAL: Thymoglobulin®|DRUG: Methylprednisolone|DRUG: Mycophenolate Mofetil|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Talk Therapy Protocol to Help Patients Make Treatment Decisions in MS
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: BEHAVIORAL: Brief Education|BEHAVIORAL: Motivational Interviewing-Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Self-Guided Online Cognitive Behavioral Strategies for Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Nervous System Diseases|Pain Management|Self Management
Interventions: DEVICE: Proactive Self Management Program for Effects of Cancer Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness Evaluation of Three Strategies of Promotion of Healthy Dietary and Physical Activity Behaviours to Prevent Weight Excess Among Teenagers
Status: COMPLETED
Conditions: Body Weight|Nutrition Processes|Prevention
Interventions: BEHAVIORAL: Educational strategy|BEHAVIORAL: Screening strategy|OTHER: Environmental strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EMRI SureScan™ Clinical Study
Status: COMPLETED
Conditions: Bradycardia|Slow Heart Beat
Interventions: DEVICE: Implantable Pulse Generator (IPG) and Pacing Leads (wires)|OTHER: Magnetic Resonance Imaging (MRI) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris
Status: COMPLETED
Conditions: Stable Angina Pectoris
Interventions: DEVICE: Active treatment group|DEVICE: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia in THR - Comparing the Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: FIB|PROCEDURE: ESPB|PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHALO! 2.0: A Mobile Technology Based Intervention to Accelerate HIV Testing and Linkage to Preventive Treatment.
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv
Interventions: BEHAVIORAL: CHALO! 2.0|BEHAVIORAL: Attention-matched control (AMC)|BEHAVIORAL: Digital coupon only (DCO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of rhBMP-2/BCP With the TSRH® Spinal System for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/BCP/TSRH® or rhBMP-2/BCP/CD HORIZON® Spinal System|DEVICE: Autograft/TSRH® or autograft/CD HORIZON® Spinal System.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid
Status: TERMINATED
Conditions: Dialysis|Cardiovascular Disease|Atherosclerosis|Inflammation
Interventions: DRUG: Extended Release Nicotinic Acid (Niaspan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine and Methadone for Opioid-dependent Chronic Back Pain Patients
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Methadone|DRUG: Buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amphiregulin Versus Non-Amphiregulin Supplementation to Maturation Culturing Medium in IVM.
Status: COMPLETED
Conditions: PCOS|IVM
Interventions: DRUG: AREG-TRIGGER|DRUG: CONTROL-TRIGGER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial on Treatments of Hirschsprung Allied Disease
Status: RECRUITING
Conditions: Complications of Treatment|Complication of Surgical Procedure|Megacolon, Not Hirschsprung
Interventions: BEHAVIORAL: conservative|PROCEDURE: operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of King Vision in Infants
Status: COMPLETED
Conditions: Orotracheal Intubation in Infants Requiring General Anaesthesia for Surgery
Interventions: PROCEDURE: Orotracheal intubation in infants with Macintosh|PROCEDURE: Orotracheal intubation in infants with King vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an Olfactory Sensory Therapeutic Group for Adolescent Patients With Restrictive Anorexia Nervosa , Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anorexia Nervosa
Interventions: OTHER: Olfactory therapeutic|OTHER: Body therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaginal Natural Orifice Trans-luminal Endoscopic Surgery Salpingectomy for Tubal Sterilization: Clinical Outcomes and Learning Curve Analysis
Status: RECRUITING
Conditions: Tubal Sterilization
Interventions: PROCEDURE: Salpingectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manipulation of the Cervical Spine on Pain Biomarkers
Status: COMPLETED
Conditions: Neck Pain, Posterior
Interventions: PROCEDURE: HVLAT manipulation|PROCEDURE: Sham HVLAT manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Safety and Immunogenicity of VAX128A, VAC128B and VAX128C Novel H1N1 Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAX128|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Detection of Mucosal Abnormalities in Graft-versus-host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DEVICE: Probe based confocal laser endomicroscopy (Cellvizio)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Calizumab Combined With Bevacizumab and Capecitabine in the Treatment of Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Carrilizumab, bevacizumab,capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of "Pílulas de Lussen®" Compared to the Pyridium® in the Symptomatic Control of Dysuria
Status: UNKNOWN
Conditions: Dysuria
Interventions: DRUG: Pílulas de Lussen|DRUG: Pyridium®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis.
Status: COMPLETED
Conditions: Non-infectious Anterior Uveitis
Interventions: DRUG: ADX-102 Ophthalmic Solution (0.5%)|DRUG: Vehicle of ADX-102 Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PERFORM-TAVR Trial
Status: UNKNOWN
Conditions: Frail Elderly|Exercise|Dietary Supplements|Postoperative Care|Rehabilitation|Transcatheter Aortic Valve Replacement
Interventions: DIETARY_SUPPLEMENT: Protein-rich oral nutritional supplement|BEHAVIORAL: Home-based supervised exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Speed Of Rewarming After CaRdiac Arrest and ThErapeutic Hypothermia
Status: COMPLETED
Conditions: Heart Arrest|Cardiac Arrest|Hypothermia
Interventions: PROCEDURE: Low Speed of Rewarming|PROCEDURE: High Speed of Rewarming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: evaluation of cancer risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Within-subject Study to Evaluate the Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: DRUG: Diclofenac sodium gel 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]talsaclidine, oral|DRUG: [14C]talsaclidine, iv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase II Trial of BIBW 2992 in Patients With HER2-negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: New-mode Clinical Target Volume Delineation of Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma by AJCC V8 Stage
Interventions: RADIATION: New-mode reduce-volume target IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing
Status: UNKNOWN
Conditions: Wounds and Injuries
Interventions: DEVICE: Altrazeal (R) Transforming Powder Dressing|OTHER: Standard of Care burn dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Stereotactic Body Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea
Status: NOT_YET_RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: DRUG: DEH113|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT