pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Leukemia Acute Myeloid - AML|Non-Hodgkin Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: TCR alfa beta T cell depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Antibiotics After Aspiration in ICU Patients
Status: RECRUITING
Conditions: Aspiration|Aspiration Pneumonia
Interventions: DRUG: Ceftriaxone|DRUG: Amoxicillin clavulanic acid|DRUG: Cefepime|DRUG: Vancomycin|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Exercise on Sleep Quality in Patients With Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Osa Syndrome
Interventions: OTHER: control|OTHER: oro-granary exercises.|OTHER: aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use TST and QFT-RD1 Test to Monitor the Tuberculous Infection in Patients, Close Contact People and Health Care Workers
Status: UNKNOWN
Conditions: Tuberculosis|Latent Tuberculosis|Tuberculosis Contact|Elderly
Interventions: DRUG: tuberculin for skin test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study on the Efficacy and Safety of the Treatment of Hyperplasia of Mammary Glands With Xiaoru Sanjie Capsule
Status: UNKNOWN
Conditions: Fibrocystic Disease of Breast
Interventions: DRUG: Xiaoru Sanjie capsules|DRUG: Xiao Yao pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time Diagnosis and Visualization of Tumor Margins in Excised Breast Specimens Using Zenith FLIM Diagnostics
Status: SUSPENDED
Conditions: Oncology|Breast Cancer|Cancer Diagnosis|Margins of Excision|Margins, Tumor-Free
Interventions: DIAGNOSTIC_TEST: Zenith FLIM Diagnostics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis
Status: RECRUITING
Conditions: Thrombolysis|Symptomatic Proximal Deep Vein Thrombosis
Interventions: DRUG: BAY3018250|DRUG: Placebo to BAY3018250
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levonorgestrel Intrauterine System For Emergency Contraception
Status: COMPLETED
Conditions: Pregnancy, Unplanned|Pregnancy; Accident
Interventions: DRUG: Ulipristal acetate|DEVICE: levonorgestrel IUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Probe-based Confocal Laser Endomicroscopy Targeted Biopsy in the Molecular Study of Undifferentiated Gastric Cancer
Status: COMPLETED
Conditions: Undifferentiated Gastric Cancer
Interventions: DEVICE: GastroFlex UHD, Cellvizio; Mauna Kea Technologies, Paris, France|DEVICE: white light endoscopy (WLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety and Effectiveness of 4R-CHOP+4R vs 6R-CHOP+2R in Newly Diagnosed Patients With DLBCL in Low Risk
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Six Courses of R-CHOP Plus Two Courses of Rituximab|DRUG: Four Courses of R-CHOP Plus Four Courses of Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BBT-401-1S in Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: BBT-401-1S first and then Placebo|DRUG: Placebo first and then BBT-401-1S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology
Status: COMPLETED
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: BEHAVIORAL: Informational Pamphlet|BEHAVIORAL: Brief Motivational Enhancement Therapy (MET) Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Nurse-based Care Coordination on Readmissions Among Primary Care Patients: a Stepped Wedge Cluster Randomized Trial
Status: COMPLETED
Conditions: Patient Activation
Interventions: OTHER: Adult Medical Care Coordination|OTHER: Remote Patient Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Fluoxetine in Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Medial Longitudinal Arch Supported Insoles on Jumping in Young Football Players
Status: COMPLETED
Conditions: Pes Planus|Sports Physical Therapy
Interventions: DEVICE: insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Application of ICG Fluorescence Cholangiography in Laparoscopic Living Donor Left Lateral Sectionectomy
Status: COMPLETED
Conditions: Living Donor Liver Transplantation
Interventions: PROCEDURE: indocyanine green (ICG) fluorescence cholangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Short Intervention During RSV Prophylaxis on Influenza Vaccination Rate.
Status: UNKNOWN
Conditions: Prematurity|RSV|Influenza|Upper Respiratory Tract Infection|Lower Respiratory Tract Infection
Interventions: BEHAVIORAL: Educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transforaminal Versus Lateralized Interlaminar Cervical Epidurals
Status: COMPLETED
Conditions: Cervicogenic Upper Extremity Radiculopathy
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Pharmacodynamic Study Comparing HLX01 And Rituximab in Patients With CD20-Positive, B-cell Lymphoma
Status: COMPLETED
Conditions: B-cell Non Hodgkin's Lymphoma
Interventions: DRUG: HLX01|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Rib Fixation Versus Medical Analgesia in Uncomplicated Rib Fractures on Pain Control.
Status: UNKNOWN
Conditions: Rib Fractures
Interventions: DEVICE: Rib fixation|DRUG: Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0249 for the Symptomatic Treatment of Alzheimer's Disease (MK0249-011)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MK0249|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Ketorolac Bupivacaine Versus Bupivacaine Alone for TAP Block in Children Undergoing Lower Abdominal Surgeries
Status: COMPLETED
Conditions: Postoperative Pain, Acute
Interventions: DRUG: Bupivacain|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: intrathecal morphine for intrathecal morphine group . bupivacaine 0.25% for Quadratus Lumborum and Erector Spinae nerve block groups .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing Intravaginal Laser Therapy to Sham in Post-menopausal Women With Recurrent Urinary Tract Infections
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection|Genitourinary Syndrome of Menopause
Interventions: DEVICE: Deka SmartXide Touch C60 (MonaLisa Touch)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Malignant Strictures in Esophagus and Gastroesophageal Junction With Covered or Partially Covered Stent.
Status: COMPLETED
Conditions: Esophageal Cancer|Cancer of Gastro Esophageal Junction|Palliative Treatment
Interventions: DEVICE: Partially covered SEMS|DEVICE: Fully covered SEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an H1N1 Influenza Vaccine in People With Asthma
Status: COMPLETED
Conditions: H1N1 Influenza Virus
Interventions: BIOLOGICAL: H1N1 vaccine high dose|BIOLOGICAL: H1N1 vaccine low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tai Chi for Relieving Aromatase Inhibitor-Induced Arthralgia in Patients With Stage I-III Breast Cancer, the TaiChi4Joint Trial
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Tai Chi|DEVICE: FitBit|OTHER: Support Group Therapy|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MEDCEM PC and MTA in Pulpotomies of Primary Molars
Status: UNKNOWN
Conditions: Evaluate the Effects of MEDCEM PC and MTA in Pulpotomies of Primary Molars.
Interventions: PROCEDURE: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Botulax® Are Not Inferior to Those of Botox® in the Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Skin Aging
Interventions: DRUG: Botulinum toxin type A(Botulax®)|DRUG: Botulinum toxin type A(Botox®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scheduled Awakenings for the Treatment of Nocturnal Enuresis
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DEVICE: Lully Sleep Guardian|DEVICE: Lully Sleep Guardian
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utidelone Injection Combined With Gemcitabine in First-line Chemotherapy for Unresectable Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Utidelone injection in combination with gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Temperature Monitoring of Adult Subjects Undergoing Outpatient Stem Cell Transplant or CAR-T Cell Therapy
Status: NOT_YET_RECRUITING
Conditions: Febrile Neutropenia
Interventions: DEVICE: IDION iTempShield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of KN046 in Subjects With Advanced Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: KN046 (Recombinant Humanized PD-L1/CTLA-4 Bispecific Single Domain Antibody Fc Fusion Protein Injection)|COMBINATION_PRODUCT: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post Approval Study to Investigate the Efficacy of Daridorexant in Subjects With Insomnia and Comorbid Nocturia
Status: COMPLETED
Conditions: Insomnia Disorder|Nocturia
Interventions: DRUG: Daridorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EmbryoGen/ Blastgen for Couples With Implantation Problems or Previous Miscarriage
Status: COMPLETED
Conditions: Recurrent Miscarriage|Infertility
Interventions: DEVICE: EmbryoGen/ BlastGen media|DEVICE: Standard Cook sequential media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant Recipients
Status: COMPLETED
Conditions: Chronic Kidney Failure|Graft vs Host Disease|Kidney Transplantation
Interventions: DRUG: Rapamune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve SystEm
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Aortic Valve Calcification|Aortic Valve Disease
Interventions: DEVICE: Lotus Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenecteplase Reperfusion Therapy in Acute Ischaemic Cerebrovascular Events-5
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Tenecteplase|DRUG: Best Practice (which may include intravenous Alteplase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Lot Consistency of V116 in Adults 18 to 49 Years of Age (V116-004, STRIDE-4)
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: V116|BIOLOGICAL: PPSV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation
Status: COMPLETED
Conditions: Constipation Drug Induced
Interventions: DRUG: Methylnaltrexone Bromide 150 mg Oral Tablet|DRUG: Methylnaltrexone Bromide 12 MG/0.6 ML Subcutaneous Solution [RELISTOR]_#1|DRUG: Naloxegol 25 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer.
Status: TERMINATED
Conditions: Chemoradiotherapy-Induced Severe Oral Mucositis
Interventions: DRUG: Clonidine HCl Mucoadhesive Buccal Tablet|DRUG: Placebo Mucoadhesive Buccal Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1, Febuxostat XR Relative Bioavailability Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Febuxostat XR 80 mg Capsule F1|DRUG: Febuxostat XR 80 mg Capsule F2|DRUG: Febuxostat XR 80 mg Capsule F3|DRUG: Febuxostat XR 80 mg Capsule F4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet Aggregation During the Shift From Clopidogrel to Ticagrelor
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: loading with Ticagrelor|DRUG: no loading with Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Evaluation of 11 C-Choline PET-CT for Detection of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: 11C-Choline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Status: NOT_YET_RECRUITING
Conditions: Obesity|Hyperlipidemias|Polycystic Ovary Syndrome|Hypertension|Coronary Heart Disease|Heart Failure|Depression, Anxiety|Type II Diabetes|Metabolic Syndrome
Interventions: BEHAVIORAL: Lifestyle counseling and coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center, Randomized, Double-blind Efficacy and Safety of CD0271 0.3%/CD1579 2.5 % Topical Gel in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CD0271 0.3% / CD1579 2.5%|DRUG: CD0271 0.1% / CD1579 2.5%|DRUG: Topical Gel Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Control and Mechanisms of Shoulder Instability in FSHD
Status: COMPLETED
Conditions: Shoulder Pain|Neuromuscular Diseases|Shoulder Injuries|Facio-Scapulo-Humeral Dystrophy|Upper Extremity Problem
Interventions: OTHER: 3D movement analysis with surface electromyography and ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Mobile Intervention (txt4TKI) for the Improvement of Tyrosine Kinase Inhibitor Management in Patients With Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase Chronic Myelogenous Leukemia
Interventions: OTHER: Text Message-Based Navigation Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and Ascites
Status: RECRUITING
Conditions: Decompensated Cirrhosis and Ascites
Interventions: DRUG: Human albumin|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swift, Certain, and Fair: Reducing Recidivism and Improving Outcomes for Alcohol and Drug Users on State Parole
Status: UNKNOWN
Conditions: Substance Abuse|Criminal Behavior
Interventions: BEHAVIORAL: SCF Supervision with Secure Confinement Sanctioning|BEHAVIORAL: SCF Supervision with Work Release Sanctioning|BEHAVIORAL: SCF Supervision with GPS Supervision Sanctioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CHAMP: Study of NVK-002 in Children With Myopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DRUG: NVK-002 Concentration 1|DRUG: NVK-002 Concentration 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan)
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sugammadex and Neostigmine at Residual Neuromuscular Blockade
Status: COMPLETED
Conditions: Residual Neuromuscular Block (TOF-ratio of 0.2)
Interventions: DRUG: Sugammadex|DRUG: Neostigmine|DRUG: Saline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of the Switch From Sirolimus to Everolimus in Stable Maintenance Renal Transplant Patients Receiving a Calcineurin Inhibitor Free Regimen
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Patients With Mild or Moderate Ulcerative Colitis Who Take a TNF Inhibitor. The Study Investigates Whether Bowel Inflammation Improves When Patients Take BI 655130 in Addition to Their Current Therapy
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CHABLIS-SC2: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Blisibimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of the BX Velocity Stent in the Treatment of De Novo Artery Lesions.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: drug-eluting stent|DEVICE: bare-metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-level Mechanical Vibration on Bone Density in Ambulant Children Affected by Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Osteoporosis|Duchenne Muscular Dystrophy
Interventions: DEVICE: Low-level mechanical vibrations WITH vertical sinusoidal acceleration|DEVICE: Low-level mechanical vibrations WITHOUT vertical sinusoidal acceleration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Simvastatin 60 mg|DRUG: Placebo|DRUG: Simvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Local Skin Safety Study of a Topical Pain Relief Spray Containing a Combination of Diclofenac, Methyl Salicylate, and Menthol
Status: WITHDRAWN
Conditions: Skin Irritation
Interventions: DRUG: Topical Spray|DRUG: Topical Gel|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Faith Moves Mountains: A Community Based Participatory Research (CBPR) Appalachian Wellness & Cancer Prevention Program
Status: COMPLETED
Conditions: Lung Cancer|Cervical Cancer|Breast Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Lay health advisor interactions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: HIPEC CO2 surgery|PROCEDURE: Standard surgery|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Nanofractional Radiofrequency Device in Arm Rejuvenation and Tightening : a Pilot Study
Status: UNKNOWN
Conditions: Skin Tightening and Rejuvenation
Interventions: DEVICE: a nanofractional radiofrequency device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin C Administration for the Prevention of Postpolypectomy Bleeding
Status: COMPLETED
Conditions: Postpolypectomy Bleeding
Interventions: OTHER: Ascorbic acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention to Change Affect Recognition and Empathy
Status: RECRUITING
Conditions: Traumatic Brain Injury|Concussion, Intermediate|Concussion, Severe|Concussion With LOC 31 to 59 Minutes|Concussion With Brief Loss of Consciousness|Traumatic Brain Injury With Brief Loss of Consciousness|Traumatic Brain Injury With Loss of Consciousness|Traumatic Brain Injury With Prolonged Loss of Consciousness|Traumatic Brain Injury (TBI); Concussion, Initial Encounter|Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter|Traumatic Brain Injury With No Loss of Consciousness|Traumatic Brain Injury With Open Intracranial Wound|Traumatic Brain Injury With Moderate Loss of Consciousness
Interventions: BEHAVIORAL: ICARE Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CAZ104|DRUG: CAZ104
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Silicone Cream Containing Allium Cepa Extract
Status: UNKNOWN
Conditions: Cicatrix
Interventions: DEVICE: silicone cream containing Allium Cepa extract|DEVICE: Commercial scar gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Audio-Visual Distraction Technique on Child's Anxiety
Status: UNKNOWN
Conditions: Anxiety, Dental|Fear, Dental
Interventions: DEVICE: Nibiru 3D Virtual Reality Headset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pneumatic Retinopexy for Primary Rhegmatogenous Retinal Detachment: To Steamroll or Not
Status: RECRUITING
Conditions: Rhegmatogenous Retinal Detachment
Interventions: OTHER: Steamroller technique|OTHER: Direct technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Injections of Paliperidone Palmitate in the Arm or Buttock of Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone Palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Registry Using Drug Eluting Stents (DES) in Patients in a Real-World Setting (DEScover Registry).
Status: COMPLETED
Conditions: Cardiovascular Diseases|Vascular Disease|Arterial Occlusive Disease|Arteriosclerosis|Atherosclerosis
Interventions: DEVICE: Cypher Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Pre-treatment Biopsy for Non-neoplastic Renal Disease vs no Biopsy on Estimated Glomerular Filtration Rate in Patients With Small Renal Mass: a Single-center, Single-blinded, Randomized, Parallel Group Clinical Trial
Status: WITHDRAWN
Conditions: Kidney Neoplasms
Interventions: PROCEDURE: Additional biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anesthetic Optimization in Pediatric LeFort Surgeries
Status: RECRUITING
Conditions: Le Fort|Pain, Postoperative
Interventions: OTHER: Standardized Anesthetic Course from Premedication to Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: BAY1193397|DRUG: BAY1193397|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension) as Second-line Therapy for Patients With KRAS Positive or Squamous Cell Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: KRAS Positive Patients With Non-small Cell Lung Cancer|Squamous Cell Non-small Cell Lung Cancer
Interventions: DRUG: BIND-014 (Docetaxel Nanoparticles for Injectable Suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Boceprevir/Peginterferon Alfa-2a/Ribavirin in Interleukin-28B CC Allele-Positive Chronic Hepatitis C Virus (HCV) Genotype 1 Participants (P07755)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: peg-Interferon alfa-2a|DRUG: Ribavirin|DRUG: Boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupuncture on Cancer-Related Cognitive Difficulties
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham Acupuncture|OTHER: Wait-List Control (WLC)|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi
Status: UNKNOWN
Conditions: Malaria|Severe Anemia
Interventions: DRUG: dihydroartemisinin-piperaquine|OTHER: message(SMS) reminder|OTHER: Health worker reminder|OTHER: short message(SMS) reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy
Status: TERMINATED
Conditions: Biochemically Recurrent Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|OTHER: Gallium Ga 68 Gozetotide|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 2nd or 3rd TKI-stop After 2 Years Nilotinib Pre-treatment in CML-patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: OTHER: TKI discontinuation|DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria
Status: COMPLETED
Conditions: Kidney Disease|Albuminuria
Interventions: DRUG: 6R BH4|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Reconstruction After Proximal Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Esophagitis, Reflux
Interventions: PROCEDURE: left-opening single-flap technique|PROCEDURE: double-flap group technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers
Status: COMPLETED
Conditions: Anesthesia
Interventions: COMBINATION_PRODUCT: One spray CTY-5339-A|DRUG: One spray CTY-5339-CB|COMBINATION_PRODUCT: Two sprays CTY-5339-A|DRUG: One spray CTY-5339-CB in combination with one spray CTY-5339-P (vehicle control: placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Intermedius Genicular Nerve in the Treatment of Patients With Chondromalacia Patella
Status: UNKNOWN
Conditions: Chondromalacia Patellae
Interventions: PROCEDURE: radiofrequency|PROCEDURE: control|DRUG: 2% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: OXEMET™ 1000 mg Coated Tablets (Metformin Hydrochloride) Bioequivalence Study. OXEMET (TM) is a Trademark of the GlaxoSmithKline Group of Companies. GLAFORNIL(TM) is a Trademark of Merck.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome
Status: RECRUITING
Conditions: Velocardiofacial Syndrome|Williams Syndrome|Fragile X Syndrome
Interventions: DRUG: methylphenidate, fluoxetin, risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Comparison of Conventional and Advanced Bipolar Energy Modalities During Laparoscopic Staging Surgery of Gynecologic Cancers
Status: COMPLETED
Conditions: Perioperative Period
Interventions: DEVICE: Ligasure-Covidien|DEVICE: RoBi forceps-Karl Storz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention and Comparison of Different Forms of Administration of Nitrates in the Risk of Radial Spasm During Coronary Angiography.
Status: COMPLETED
Conditions: Coronaropathy
Interventions: DRUG: dinitrate isosorbide|DRUG: nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Double Blind, Placebo Control, Bariatric IV Ace
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: intravenous acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction
Status: COMPLETED
Conditions: Post COVID-19 Condition
Interventions: DEVICE: Hi-OxSR Sequential Rebreathing mask (oxygen concentrator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing Breast Cancer With Al18F-NOTA-FAPI-04 PET/CT (PFB-02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Al18F-NOTA-FAPI-04 PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Olaratumab (LY3012207) in Participants With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Olaratumab|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Microvascular Coronary Artery Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy Adults
Status: RECRUITING
Conditions: Vaccine Reaction
Interventions: DRUG: FMP013|DRUG: ALFQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment
Status: COMPLETED
Conditions: Severe Hepatic Impairment
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Choice of Treatment Methods and Efficacy of LABC
Status: RECRUITING
Conditions: Locally Advanced Breast Cancer
Interventions: PROCEDURE: Modified radical mastectomy for breast cancer|PROCEDURE: neoadjuvant therapy|PROCEDURE: Systematic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Efficacy and Safety of Short Duration of DAPT After Genoss DES Stent Implantation in Patients
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention|Dual Antiplatelet Therapy
Interventions: DEVICE: Genoss DES stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Injection Molding Technique: A Minimally Invasive Management for Enamel Hypoplasia Affecting Permanent Anterior Teeth in Children
Status: RECRUITING
Conditions: Enamel Hypoplasia
Interventions: OTHER: Injectable composite resin restoration|OTHER: Injectable giomer restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ocrelizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Ocrelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Continuous Glucose Monitoring in Participants With Type 2 Diabetes Mellitus (MK-0000-258 AM2)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure"
Status: COMPLETED
Conditions: Liver Cirrhosis|Liver Failure
Interventions: PROCEDURE: Plasma exchange with albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial
Status: COMPLETED
Conditions: Staph Aureus Colonization|Staph Aureus Infection
Interventions: DRUG: Mupirocin and Chlorhexidine|DRUG: Placebo ointment and placebo cloths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Concentrating on Antisepsis: 5% vs. 10% Povidone-Iodine Prior to Intravitreal Injection
Status: UNKNOWN
Conditions: Endophthalmitis|Eye Infections
Interventions: BIOLOGICAL: Bacterial Culture Swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Stability of Dental Implant Placed Simultaneously With Closed Sinus Lifting Using Hydraulic Lift Technique Versus Summer's Osteotome Technique in Posterior Edentulous Maxilla (RCT)
Status: UNKNOWN
Conditions: Evaluations, Diagnostic Self
Interventions: DEVICE: Hydrolic lifter device|BEHAVIORAL: Patient satisfaction evalution using hydraulic lifter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib and Dexamethasone in Treating Patients With Multiple Myeloma Who Previously Underwent a Stem Cell Transplant
Status: WITHDRAWN
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: carfilzomib|DRUG: dexamethasone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Large-vessel Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Atorvastatin 40 Mg Oral Tablet|DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Transcutaneous vagal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of D-Cycloserine in Children With Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard and Endoscope Assisted Endotracheal Intubation
Status: UNKNOWN
Conditions: Biliary Tract Diseases|Pancreatic Diseases
Interventions: PROCEDURE: Endoscope assisted endotracheal intubation [EAEI]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Short Infusion Vs. Fixed Dose of Cisplatin + Gemcitabine in Non Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Information Leaflets in Adult Aural Rehabilitation
Status: COMPLETED
Conditions: Hearing Impairment
Interventions: BEHAVIORAL: Information leaflets with illustrations about hearing aid functions|BEHAVIORAL: Information leaflets with only text about hearing aid functions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group (PENG) block|PROCEDURE: Spinal anesthesia|DRUG: Intrathecal morphine|PROCEDURE: Sham PENG block|DRUG: Intrathecal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Corticosteroid for Post Extubation Stridor in Children
Status: COMPLETED
Conditions: Stridor
Interventions: DRUG: fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy
Status: COMPLETED
Conditions: Hemangiomas
Interventions: DRUG: prednisolone|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT