pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Preoperative Abdominal Exercises and Russian Current on Muscle Strength Post Ventral Hernioplasty
Status: COMPLETED
Conditions: Muscle Strength
Interventions: OTHER: Graduated abdominal strengthening exercises|DEVICE: The Russian current stimulation|COMBINATION_PRODUCT: Graduated abdominal strengthening exercises and the Russian current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of the Urinary Nerve Growth Factor in the Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy With Outflow Obstruction|Overactive Detrusor
Interventions: PROCEDURE: Holmium Laser Enucleation of the Prostate (HoLEP)|DEVICE: Holmium laser enucleation system and morcellator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Body Weight Loading on Urinary Electrolyte Excretion
Status: COMPLETED
Conditions: Obesity|Edema
Interventions: OTHER: Heavy Casall HIT weight vest|BEHAVIORAL: Standing|DIETARY_SUPPLEMENT: Water load|BEHAVIORAL: Sitting|OTHER: Light Casall HIT weight vest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis
Status: COMPLETED
Conditions: Acute Lithiasic Cholecystitis Grade I or II|Symptoms Lasting for Less Than 5 Days|Required Cholecystectomy|Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days
Interventions: DRUG: Amoxicillin clavulanic acid|OTHER: No medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Acquired Immunodeficiency Syndrome
Interventions: DRUG: cisplatin|RADIATION: external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Albiglutide in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|BIOLOGICAL: albiglutide uptitration|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Oral Fampridine-SR in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Placebo|DRUG: 10 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP)|DRUG: 15 mg fampridine-SR (4-aminopyridine, 4-AP)|DRUG: 20 mg fampridine-SR (4-aminopyridine, 4-AP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Sensitizing Potential of HAT1 Topical Products Using Skin Sensitivity Patch Tests
Status: COMPLETED
Conditions: Healthy|Atopic Dermatitis|Psoriasis
Interventions: DRUG: HAT1|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Methotrexate Induced Nephrotoxicity and Prolonged Drug Elimination Time With 12 Hours Prehydration
Status: COMPLETED
Conditions: Methotrexate Induced Nephrotoxicity
Interventions: OTHER: 12 hours of prehydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dietary Fiber Effects on the Microbiome and Satiety
Status: RECRUITING
Conditions: Dietary Fiber
Interventions: OTHER: Dietary fiber: 10-25g|OTHER: Dietary fiber: 5g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autonomic Modulation Recovery After Acute Resistance Exercise
Status: COMPLETED
Conditions: Resistance Training
Interventions: OTHER: Resistance Training - UL endurance protocol|OTHER: Resistance Training - UL strength protocol|OTHER: Resistance Training - LL endurance protocol|OTHER: Resistance Training - LL strength protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Stimulation on the Autonomous Nerve System in Healthy Young People
Status: COMPLETED
Conditions: Healthy Volunteers|Cardiovascular System|Autonomic Nervous System
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation (t-VNS)|DEVICE: Transcutaneous Sympathetic Ganglion Electrical Stimulation (t-SES)|DEVICE: Sham Transcutaneous vagus nerve stimulation (Sham t-VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ROSE for Improved Molecular Marker Testing Via EBUS
Status: ENROLLING_BY_INVITATION
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: OTHER: ROSE (presence of cytotech)|OTHER: NO-ROSE (absence of cytotech)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Morphine Slow-release Capsules in Substitution Therapy
Status: COMPLETED
Conditions: Opiate Dependent
Interventions: DRUG: Sevre-Long™|DRUG: Slow release oral morphine|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Assess Radiofrequency Diathermocontraction Device For Muscle Stimulation And The Treatment Of Abdominal Fat
Status: TERMINATED
Conditions: Muscle Stimulation|Abdominal Fat
Interventions: DEVICE: Brera
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics Supplementation in Premature Infants
Status: COMPLETED
Conditions: Prematurity
Interventions: DIETARY_SUPPLEMENT: Probiotic supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minimally Invasive Right Colectomy Anastomosis Study
Status: UNKNOWN
Conditions: Colorectal Cancer|Anastomotic Complication|Colectomy
Interventions: PROCEDURE: Extracorporeal Anastomosis|PROCEDURE: Intracorporeal Anastomosis|PROCEDURE: Robotic Surgery|PROCEDURE: Laparoscopic Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Wellness Intervention for Smoking and HIV
Status: RECRUITING
Conditions: HIV|Sleep|Smoking Cessation|Cardiovascular Diseases
Interventions: DRUG: Varenicline|BEHAVIORAL: Smoking Cessation Counseling|BEHAVIORAL: Health Approach 1 to Reduce Smoking|OTHER: Health Approach 2 to Reduce Smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
Status: RECRUITING
Conditions: Toxoplasmosis
Interventions: DRUG: Leucovorin calcium|DRUG: Pyrimethamine|DRUG: Spiramycin|DRUG: Sulfadiazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Familial Pulmonary Fibrosis|Idiopathic Interstitial Pneumonia|Familial Interstitial Pneumonia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Islet After Kidney Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Islet transplantation|BIOLOGICAL: Antithymocyte Globulin|BIOLOGICAL: Daclizumab or Basiliximab|BIOLOGICAL: Etanercept|BIOLOGICAL: Allogenic human purified pancreatic islets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke (SENTIS)
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DEVICE: NeuroFlo™ catheter|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Resiliency Collective Efficacy Intervention
Status: RECRUITING
Conditions: Violence, Physical|Violence, Non-accidental|Violence, Sexual|Violence, Domestic|Violence, Structural|Violence in Adolescence|Community Violence|Social Cohesion
Interventions: BEHAVIORAL: Community Resiliency Collective Efficacy Intervention (CRCEI)|BEHAVIORAL: Health Education Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion
Status: COMPLETED
Conditions: Otitis Media With Effusion
Interventions: DRUG: lansoprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Audible Leak Test
Status: COMPLETED
Conditions: Anesthesia Intubation Complication|Mechanical Ventilation Complication
Interventions: OTHER: Assess for Audible Endotracheal Leak|OTHER: Assess for Endotracheal Leak with direct visualization under rigid bronchoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)
Status: COMPLETED
Conditions: Degenerative Disc Disease|Intervertebral Disc Disease|Low Back Pain
Interventions: BIOLOGICAL: Allogenic Mesenchymal Stromal Cells|DRUG: Mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)
Status: TERMINATED
Conditions: Cystic Fibrosis|Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Omalizumab|DRUG: Placebo|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care
Status: RECRUITING
Conditions: Alcohol-induced Disorders|Alcohol Drinking|Mental Health
Interventions: BEHAVIORAL: Strengths-based linkage to alcohol care|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma
Status: UNKNOWN
Conditions: Neoadjuvant Therapy of Locally Advanced Upper Urinary Tract Urothelial Carcinoma
Interventions: DRUG: Immunotherapy combined with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTSD Treatment for Incarcerated Men and Women: WPP
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Therapist-facilitated Support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of APN1125 in Subjects With Schizophrenia
Status: SUSPENDED
Conditions: Schizophrenia
Interventions: DRUG: APN1125|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amaryl-M 2/500 mg|DRUG: Amaryl-M 1/500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Amitriptyline|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HHHFNC (Heated Humidified High-Flow Nasal Cannula) Versus NCPAP for Respiratory Distress Syndrome of Prematurity
Status: COMPLETED
Conditions: Newborn Respiratory Distress Syndrome
Interventions: DEVICE: HHHFNC|DEVICE: NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]|DEVICE: AcrySof® IQ Monofocal IOL Model SN60WF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resorbable Barrier for the Prevention of Abdominal and Peri-hepatic Adhesion Formation
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: - use of resorbable membrane Seprafilm|PROCEDURE: without resorbable barrier (seprafilm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ZN-e4 in Subjects With Epidermal Growth Factor Receptor Mutated Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: ZN-e4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Effectiveness Study of Two Interventions Aimed at Reducing Impact Loads in Runners
Status: COMPLETED
Conditions: Musculoskeletal Injury
Interventions: OTHER: Increased running cadence gait retraining|OTHER: Forefoot Strike gait retraining|OTHER: Strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nephroprotective Effect of Pentoxifylline Against Cisplatin in Patients With Head and Neck Cancer
Status: NOT_YET_RECRUITING
Conditions: Pentoxifylline, Cisplatin, Nephrotoxixcity
Interventions: DRUG: Pentoxifylline 400 mg SR tablets|DRUG: cisplatin with standard hydration with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy
Status: COMPLETED
Conditions: Periimplantitis|Peri-implant Mucositis
Interventions: DEVICE: Chitosan brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Bulk-fill Alkasite Restoration Versus Resin Modified Glass Ionomer in Adult With Class V Carious
Status: UNKNOWN
Conditions: Cervical Lesion
Interventions: OTHER: Alkasite bioactive restorative material.|OTHER: Resin Modified Glass Ionomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Aripiprazole 6-week group|DRUG: Aripiprazole 8-week group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Gastroprotective Effect of Carvedilol in Patients With Ischemic Heart Disease on Aspirin Therapy
Status: UNKNOWN
Conditions: IHD|Gastro-Intestinal Disorder|Aspirin Induced Esophageal Ulcer
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
Status: COMPLETED
Conditions: Scabies|Yaws|Impetigo
Interventions: DRUG: Ivermectin|DRUG: Azithromycin|DRUG: Permethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an H1N1 Influenza Vaccine in HIV Infected Pregnant Women
Status: COMPLETED
Conditions: HIV Infections|H1N1 Influenza Virus
Interventions: BIOLOGICAL: Influenza A (H1N1) monovalent vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intratumoral Dendritic Cell Vaccination Combined With Local Radiotherapy in Patients With Recurrent Lymphoma.
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: Autologous dendritic cells generated using GM-CSF, interferon alpha and LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Topical Aloe Vera Gel in Emergency Department Patients Presenting With Simple Traumatic Wounds
Status: WITHDRAWN
Conditions: Injuries and Wounds
Interventions: DRUG: Aloe Vera Gel|OTHER: Ultrasound gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic Hydroxyapatite
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastro Esophageal Reflux|Dental Erosion
Interventions: OTHER: Domiciliary use of Biorepair Total Protection + Biorepair Shock Treatment|OTHER: Biorepair Total Protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stent Graft, Sirolimus Stent, and Bare Metal Stent Implanted in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Use of Topical Imipramine in Reducing Ultraviolet B Induced Microvesicle Particle Release in Photosensitive Subjects
Status: RECRUITING
Conditions: Photosensitivity|Microvesicle Particle
Interventions: DRUG: 4% Imipramine Cream|DRUG: Base Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products
Status: COMPLETED
Conditions: Sleep|Mood|Caffeine Withdrawal|Anxiety|Productivity
Interventions: OTHER: Clevr Sleeptime|OTHER: Clevr Matcha|OTHER: Clevr Chai
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Technosphere® Insulin Inhalation Powder|DRUG: Technosphere® Insulin Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
Status: UNKNOWN
Conditions: Schizophrenia, Catatonic|Schizophrenia, Disorganized|Schizophrenia, Paranoid|Schizophrenia|Psychotic Disorders
Interventions: DRUG: Long-acting Risperidone microspheres injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Androgen Ablation Therapy With or Without Vaccine Therapy in Treating Patients With Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: GVAX prostate cancer vaccine|DRUG: bicalutamide|DRUG: goserelin|DRUG: leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ADG20 for the Prevention of COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: ADG20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver Disease
Status: UNKNOWN
Conditions: Short Bowel Syndrome|Cholestasis
Interventions: DRUG: Omegaven Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin at Elective Cesarean Delivery Part 2
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Carbetocin|DRUG: Carbetocin|DRUG: Carbetocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEYOND Pilot Study
Status: COMPLETED
Conditions: Multiple Sclerosis|Relapsing-Remitting
Interventions: DRUG: Betaseron (Interferon beta-1b, BAY86-5046)|DRUG: Betaseron (Interferon beta-1b, BAY86-5046)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication: A Randomized Clinical Trial of 10 and 14 Days
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Tetracycline|DRUG: Metronidazole|DRUG: Bismuth Potassium Citrate|DRUG: Colloidal Bismuth Pectin|DRUG: Vonoprazan fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIving BEtteR With asThma studY:: A Multimodal Intervention to Address Multimorbidity in Difficult Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma|Multi Morbidity
Interventions: BEHAVIORAL: Behaviour change|BEHAVIORAL: Dietary support|BEHAVIORAL: Breathing pattern retraining|BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Laboratory Study of ASP8062 for Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcohol Drinking|Alcohol Use Disorder (AUD)
Interventions: DRUG: ASP8062|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of FOLFOX-4 Plus Cetuximab Versus UFOX Plus Cetuximab.
Status: COMPLETED
Conditions: Previously Untreated Metastatic Colorectal Cancer
Interventions: DRUG: UFOX + Cetuximab|DRUG: FOLFOX4 + Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SelfFit Mobile Medical App for Hearing Loss Diagnostics and Hearing Device Fitting / Fine Tuning
Status: COMPLETED
Conditions: Mild to Moderate Sensorineural Hearing Loss
Interventions: DEVICE: SelfFit adjusted hearing device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HMB for Denutrition in Patients With Cirrhosis (HEPATIC)
Status: COMPLETED
Conditions: Sarcopenia|Cirrhosis|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ensure Plus Advance|DIETARY_SUPPLEMENT: Ensure High Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Hurler
Status: COMPLETED
Conditions: Mucopolysaccharidosis I|Mucopolysaccharidosis VI|Mannosidosis|Mucolipidosis Type II (I-cell Disease)
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Busulfan, Cyclophosphamide, ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin Before Autologous Stem Cell Transplant in Treating Patients With Hodgkin Lymphoma
Status: COMPLETED
Conditions: Recurrent Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans
Status: COMPLETED
Conditions: Chronic Pain|Traumatic Brain Injury|Posttraumatic Stress Disorder|Depression|Opioid Use Disorder
Interventions: BEHAVIORAL: FORT-A|OTHER: VA Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Surface Syndrome Post-lasik, Outcomes of Treatment With Platelet Rich Plasma
Status: COMPLETED
Conditions: Dry Eye After LASIK-Laser in Situ Keratomileusis
Interventions: BIOLOGICAL: PRP autologous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and S1 (DS) Versus S1 and Cisplatin (SP) in Curatively Resected Stage IIIB/IV Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: DS|DRUG: SP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Flow Nasal Cannula (HFNC) Preoxygenation in Obese Patients Undergoing General Anesthesia
Status: COMPLETED
Conditions: Preoxygenation|Anesthesia|Obesity
Interventions: DEVICE: High Flow Nasal Cannula (HFNC)|DEVICE: Standard anesthesia FaceMask (FM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis|7.0 Tesla Magnetic Resonance Imaging|Hand Vascular Involvement|Hand Osteoarticular Involvement
Interventions: DEVICE: 7.0 T RMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose Epirubicin-Cyclophosphamide Regeneration
Status: RECRUITING
Conditions: Localized Breast Cancer
Interventions: DRUG: Dense dose epirubicin-cyclophosphamide chemotherapy and G-CSF (filgrastim, lenograstim)|DRUG: Dense dose epirubicin-cyclophosphamide chemotherapy with administration of peg-G-CSF (pegfilgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pasta and Couscous Prepared With Durum Wheat Semolina: Effect on Post-prandial Glucose and Insulin Metabolism
Status: COMPLETED
Conditions: Dietary Modification
Interventions: OTHER: Short pasta (dry)|OTHER: Long pasta (dry)|OTHER: Couscous|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Malignant Solid Tumors
Interventions: DRUG: enfortumab vedotin|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in Adults 65 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Bio's influenza vaccine GSK2186877A|BIOLOGICAL: Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CPI-613 in Combination With Bendamustine in Patients With Relapsed/Refractory T-Cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Relapsed T-Cell Lymphoma|Refractory T-Cell Lymphoma|Non Hodgkin Lymphoma
Interventions: DRUG: CPI 613|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calorimetry Guided Nutrition vs. Recommended Daily Intake in Weaning Chronically Ventilated Patients: Double Blind RCT.
Status: ACTIVE_NOT_RECRUITING
Conditions: Mechanical Ventilation
Interventions: OTHER: Nutrition and fluid plans prepared using calorimetry-based measurements.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biomarker Study of Pancreatic Neuroendocrine Tumours
Status: RECRUITING
Conditions: Pancreatic Neuroendocrine Tumor
Interventions: RADIATION: 18F-FDG-PET|RADIATION: 68Ga-DOTATOC-PET|RADIATION: Computed tomography|OTHER: Core needle biopsy|OTHER: Phlebotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-term High Precision Radiotherapy for Early Prostate Cancer With Concomitant Boost on the Dominant Lesion
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of Prostate
Interventions: RADIATION: External beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chronic Consumption of a Cranberry Beverage on Inflammation and Oxidative Stress
Status: COMPLETED
Conditions: Inflammation
Interventions: OTHER: Cranberry|OTHER: Non-Cranberry beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices
Status: RECRUITING
Conditions: Esophageal Varices|Liver Cirrhoses|Bleeding Esophageal Varices|Upper Gastrointestinal Bleeding
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Lurasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax
Status: COMPLETED
Conditions: Pneumothorax
Interventions: PROCEDURE: Modified thoracoscopic technique|PROCEDURE: Axillary mini-thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Safety of Two Asparaginase Preparations in Children With Previously Untreated Acute Lymphoblastic Leukaemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: asparaginase|DRUG: recombinant asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mucosave® on Gastrointestinal Discomfort
Status: COMPLETED
Conditions: Gastrointestinal Discomfort
Interventions: DIETARY_SUPPLEMENT: Mucosave® capsules|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Rehabilitation Program With Pulsed Electromagnetic Field Therapy in Patients With Post-covid Sequelae.
Status: UNKNOWN
Conditions: COVID-19
Interventions: DEVICE: Pulsed ectromagnetid field therapy|OTHER: Pulmonary rehabilitation program (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Placebo|DRUG: Permitted DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: Nutrition specialist|DIETARY_SUPPLEMENT: Ensure Surgery Immunonutrition shakes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neolexon® Aphasia-App in Acute Aphasia After Stroke
Status: UNKNOWN
Conditions: Aphasia, Acquired|Stroke, Acute
Interventions: DEVICE: Neolexon|OTHER: Speech therapy|OTHER: Self training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Gaucher's Disease
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Medical Device for the Treatment of Toenail Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis of Toenail
Interventions: DEVICE: Excilor Forte|DRUG: Loceryl 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qualitative & Quantitative Comparison of Hydrostatic vs Vacuum Casting Methods in Trans-Tibial Amputees
Status: COMPLETED
Conditions: Hydrostatic Vacuum Casting
Interventions: OTHER: vacuum casting|OTHER: hydrostatic casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exploring the Effectiveness of the 'Back of the Net' Intervention on Indices of Physical and Psychological Measures
Status: COMPLETED
Conditions: Self Concept|Body Fat Composition|Depression|Perceived Social Support
Interventions: OTHER: Exercise|BEHAVIORAL: Online Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Filgrastim|BIOLOGICAL: Genetically Engineered Lymphocyte Therapy|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Plerixafor|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailoring Online Continence Promotion
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence in Old Age|Fecal Incontinence in Old Age
Interventions: BEHAVIORAL: Online Continence promotion program without tailoring|BEHAVIORAL: Online Continence promotion program with tailoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Extension of Safety and Efficacy of Vagus Nerve Stimulator in Patients With Rheumatoid Arthritis (RA)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: SetPoint Medical Neurostimulation of the Cholinergic Anti-inflammatory Pathway System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of PGDM1400 and PGT121 and VRC07-523LS Monoclonal Antibodies in HIV-infected and HIV-uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PGDM1400/Placebo (3mg/kg IV)|BIOLOGICAL: PGDM1400/Placebo (10mg/kg IV)|BIOLOGICAL: PGDM1400/Placebo (30mg/kg IV)|BIOLOGICAL: PGDM1400 + PGT121/Placebo (3mg/kg + 3mg/kg IV)|BIOLOGICAL: PGDM1400 + PGT121/Placebo (10mg/kg + 10mg/kg IV)|BIOLOGICAL: PGDM1400 + PGT121/Placebo (30mg/kg + 30mg/kg IV)|BIOLOGICAL: PGDM1400 + PGT121 + VRC07-523LS (20mg/kg + 20mg/kg + 20 mg/kg IV)|BIOLOGICAL: PGDM1400 + PGT121 (MTD IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Safety and Efficacy on Neuromyopathy of Early Standing With the Assistance of Tilt Table in Critically Patients
Status: COMPLETED
Conditions: Patients Are Recruited From One Thoracic and Cardiac Surgery ICU
Interventions: DEVICE: the standard physiotherapy group|DEVICE: standing table group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LB1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia
Status: WITHDRAWN
Conditions: COVID-19|Coronavirus Disease 2019|Covid19|COVID-19 Pneumonia
Interventions: DRUG: LB1148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Butyrate Enemas on Visceral Perception
Status: COMPLETED
Conditions: Visceral (Hyper)Sensitivity
Interventions: DRUG: Butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pulsed-field Ablation in Patients With Persistent Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Persistent Atrial Fibrillation|Pulsed-field Ablation
Interventions: DEVICE: pulsed-field ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Inflammation
Interventions: BIOLOGICAL: Ziltivekimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
Status: WITHDRAWN
Conditions: Chronic Kidney Failure|Chronic Kidney Disease stage3|Chronic Kidney Disease, Stage 4 (Severe)|Chronic Kidney Disease Stage 5|Fatigue
Interventions: DIAGNOSTIC_TEST: Discrimination of neuromuscular alterations protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Different Ventilation Mode During One-lung Ventilation
Status: COMPLETED
Conditions: Thoracic Surgery|One Lung Ventilation|Ventilator-Induced Lung Injury
Interventions: OTHER: VCV mode|OTHER: PCV mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia
Interventions: DRUG: Galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vedolizumab Subcutaneous (SC) as Maintenance Therapy in Crohn's Disease (CD)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab SC 108 mg|DRUG: Placebo|DRUG: Vedolizumab IV 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Lidocaine Spray for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation
Status: COMPLETED
Conditions: Pain Alleviation|Dilatation and Evacuation|Laminaria Placement
Interventions: DRUG: Lidocaine|OTHER: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Miltefosine Plus Topical Paromomycin In American Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis, American
Interventions: DRUG: Miltefosine and Paromomycin|DRUG: miltefosine|DRUG: paromomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Text-Based Adherence Game for Young People Living With HIV in Ghana
Status: COMPLETED
Conditions: HIV/AIDS|Medication Adherence
Interventions: BEHAVIORAL: Text-Based Adherence Game|BEHAVIORAL: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Denosumab for Treating Periprosthetic Osteolysis.
Status: UNKNOWN
Conditions: Osteolysis
Interventions: DRUG: Denosumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain
Status: COMPLETED
Conditions: Post Surgical Ocular Inflammation and Pain
Interventions: DRUG: KPI-121 1% Ophthalmic Suspension dosed BID|DRUG: Vehicle of KPI-121 Ophthalmic Suspension dosed BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Identification of Anti-tumor Necrosis Factor (TNF) α Agent's Efficacy in Ankylosing Spondylitis Patients
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise as Adjunctive Treatment for Refractory Epilepsy
Status: TERMINATED
Conditions: Refractory Epilepsy|Epilepsy
Interventions: BEHAVIORAL: Exercise program|BEHAVIORAL: Health Coach|BEHAVIORAL: Health Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura
Status: RECRUITING
Conditions: Henoch-Schönlein Purpura|Gastrointestinal Injury|Mycophenolate Mofetil
Interventions: DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibition: Uric Acid Excretion Study
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Benzbromaron|DRUG: Empagliflozin 25 MG + benzbromarone 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT