pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oxytocin and Dyadic Psychotherapy in the Treatment of Post Partum Depression
Status: UNKNOWN
Conditions: Postpartum Depression
Interventions: DRUG: Oxytocin|DRUG: placebo|BEHAVIORAL: Dyadic psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Study of PTHrP and PTH to Treat Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Parathyroid hormone related protein (1-36)|DRUG: Parathyroid hormone related protein(1-36)|DRUG: Parathyroid hormone (1-34)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
Status: UNKNOWN
Conditions: Headache|Epilepsy|Dizziness
Interventions: DRUG: Contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Staple Line Inversion vs Buttressing on Postoperative Vomits After LSG
Status: UNKNOWN
Conditions: Vomiting, Postoperative
Interventions: PROCEDURE: Staple line inversion|COMBINATION_PRODUCT: Staple line buttressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Status: COMPLETED
Conditions: Lead, Blood|Pregnancy|Bone Resorption
Interventions: DIETARY_SUPPLEMENT: calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Avastin and Tarceva for Locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Avastin|DRUG: Tarceva
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Connective Tissue Massage in Women With Primary Dysmenorrhoea
Status: COMPLETED
Conditions: Dysmenorrhea|Pelvic Pain
Interventions: OTHER: lifestyle advice|OTHER: connective tissue manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Related Anemia in Patients With Non-Myeloid Malignancies
Status: COMPLETED
Conditions: Lymphoma|Breast Neoplasms|Lung Neoplasms|Multiple Myeloma|Chronic Lymphocytic Leukemia
Interventions: DRUG: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Typical antipsychotic|DRUG: Risperidone|DRUG: Olanzapine|DRUG: Quetiapine|DEVICE: Aripiprazole|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Rapamycin 3mg|DRUG: Rapamycin 6mg|PROCEDURE: Radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Dysfunction Associated Fatty Liver Disease in Long-Term Cholecystectomy Patients
Status: COMPLETED
Conditions: Liver Steatoses
Interventions: DIAGNOSTIC_TEST: USG, blood tests, waist, hip, height and blood pressure measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Carcinoma|Metastatic Carcinoma|Hormone Receptor Positive Tumor
Interventions: DRUG: AZD2014|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Postoperative Pain After Milligan-Morgan Haemorrhoidectomy With Application of Vitamin E Ointment
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Vitamin E ointment application|DRUG: Vaseline ointment application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dapivirine (DPV) Vaginal Ring (VR)|DRUG: Truvada Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate Pharmacokinetics and Pharmacodynamics of Z-215 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Z-215 10mg|DRUG: Z-215 20mg|DRUG: Rabeprazole Sodium 10mg|DRUG: Rabeprazole Sodium 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacillus Calmette-guérin Vaccination to Prevent Infections of the Elderly
Status: COMPLETED
Conditions: Infection|Hospitalization|Mortality
Interventions: BIOLOGICAL: Vaccination|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of BCD-217 (Anti-CTLA-4 and Anti-PD-1) Followed By BCD-100 (Anti-PD-1) Versus BCD-100 Monotherapy as First-Line Treatment in Patients With Unresectable or Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Melanoma Metastatic
Interventions: BIOLOGICAL: BCD-217|BIOLOGICAL: BCD-100|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Impact of Each Component of the Biliopancreatic Diversion With Duodenal Switch and Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Biliopancreatic Diversion With Duodenal Switch|Gastrectomy
Interventions: PROCEDURE: Gastrectomy|PROCEDURE: BPD-DS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Monitor the Use of an Amino Acid-Based Infant Formula
Status: COMPLETED
Conditions: Cow's Milk Protein Allergy|Eosinophilic Gastrointestinal Disorders|Malabsorption/Maldigestion|Short Bowel Syndrome|Multiple Food Allergies
Interventions: OTHER: Free amino acid infant formula
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability Study of Valganciclovir Hydrochloride Tablets 450 mg Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valganciclovir Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Interval Training Recuperates Capacity of Endogenous Thrombin Generation in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|High-intensity Interval Training
Interventions: BEHAVIORAL: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01)
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic|Proteinuria
Interventions: DRUG: Lisinopril|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Computerized Vestibular Function Assessment and Training System Combined With Cognitive/Motor Dual-task
Status: ENROLLING_BY_INVITATION
Conditions: Vestibular Function Disorder|Cognitive Decline|Dizziness|Vestibular Abnormality
Interventions: OTHER: Traditional vestibule rehabilitation training|OTHER: Dual-task vestibule rehabilitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
Status: RECRUITING
Conditions: Complex Atypical Hyperplasia|Endometrial Cancer
Interventions: DRUG: 18F-fluorofuranylnorprogesterone PET / MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess Efficacy and Safety of Anti-von Willebrand Factor (vWF) Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)
Status: COMPLETED
Conditions: Acquired Thrombotic Thrombocytopenic Purpura
Interventions: BIOLOGICAL: Caplacizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Famitinib in Combination With HS-10296 in Patients With EGFR-mutant NSCLC
Status: UNKNOWN
Conditions: EGFR-mutant Non-Small Cell Lung Cancer
Interventions: DRUG: famitinib po|DRUG: HS-10296 po
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: tiotropium high dose|DRUG: placebo|DRUG: tiotropium low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation
Status: RECRUITING
Conditions: Transthyretin Cardiac Amyloidosis
Interventions: DRUG: Tafamidis 61 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Interactive Floor on Postoperative Pain and Mobilization of Children
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain Management
Interventions: OTHER: İnteractive floor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intracranial Pressure in Monopolar and Bipolar Hysteroscopy
Status: COMPLETED
Conditions: Intracranial Pressure Increase
Interventions: PROCEDURE: Monopolar hysteroscopy|PROCEDURE: Bipolar hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study)
Status: COMPLETED
Conditions: Sickle Cell Disease|Acute Chest Syndrome
Interventions: DRUG: Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: BIOLOGICAL: Hematopoietic stem cells from bone marrow or peripheral blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiomics-based Surrogate of Endoscopy (rEndosc) (CHESS1703)
Status: WITHDRAWN
Conditions: Esophageal Varices in Cirrhosis of the Liver
Interventions: PROCEDURE: Endoscopy|PROCEDURE: CTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventive stRategy for IMMU132-relatED AEs in TNBC - PRIMED
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer|Breast Cancer
Interventions: DRUG: Sacituzumab govitecan|DRUG: Loperamide|DRUG: Granulocyte Colony-Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Multiple Oral Doses of BI 1356 BS on Pharmacokinetics, Safety and Tolerability of Multiple Oral Doses of Simvastatin and on the Pharmacokinetics of Its Metabolite Simvastatin Acid in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Simvastatin|DRUG: 10 mg BI 1356 BS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis
Status: COMPLETED
Conditions: Perforated Appendicitis
Interventions: DRUG: Ampicillin, gentamicin, clindamycin, flagyl, ceftazidime
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ALXN1840 Versus Standard of Care in Pediatric Participants With Wilson Disease
Status: TERMINATED
Conditions: Wilson Disease
Interventions: DRUG: ALXN1840|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial
Status: UNKNOWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players
Status: COMPLETED
Conditions: Brain Trauma
Interventions: OTHER: Plasma Neurofilament Light (NF-L)|OTHER: Omega-3 Index|OTHER: HeadCount Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Recombinant Humanized Anti-PD-1 Monoclonal Antibody for Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: humanized anti-PD-1 monoclonal antibody toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Painful Breastfeeding and Osteopathic Treatment on the Mother-newborn Dyad
Status: COMPLETED
Conditions: Painful Breastfeeding
Interventions: OTHER: Breastfeeding usual known aids and osteopathic treatment|OTHER: Breastfeeding usual known aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson Disease|Healthy Adult
Interventions: DEVICE: Cerebellar transcranial direct current stimulation at 4 mA|DEVICE: Sham cerebellar transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib Plus Nimotuzumb for NSCLC
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: afatinib (30 or 40mg) + nimotuzumab (100 or 200mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation
Status: COMPLETED
Conditions: Acute Lung Injury (ALI) Due to Coronavirus Disease-2019 (COVID-19)
Interventions: DRUG: Nezulcitinib (TD-0903) Dose A|DRUG: Nezulcitinib (TD-0903) Dose B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mannitol on Postreperfusion Syndrome During Living Donor Liver Transplant
Status: COMPLETED
Conditions: Liver Transplant Disorder
Interventions: DRUG: Mannitol|OTHER: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: BetaFIT Study: Beta Cell Imaging After Faecal mIcrobiota Transplantation
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: 68Ga-NODAGA-Exendin-4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Effect of Preemptive and Post-operative Erector Spina Plane Block on Intraoperative Opioid Consumption and Postoperative Analgesia in Patients Who Will Undergo Elective Thoracotomy Surgery, Guided by the Nociception Level Index (NoL)
Status: COMPLETED
Conditions: Erector Spina Plan Block|Preemptive Analgesia|Thoracotomy|Nociception Level Index(NoL)
Interventions: PROCEDURE: Erector Spina Plan Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone Gel|DRUG: Dapsone Gel Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MB-CART19.1 in Patients With R/R ALL
Status: UNKNOWN
Conditions: Precursor B-Lymphoblastic Lymphoma/Leukaemia Refractory
Interventions: DRUG: MB-CART19.1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLOOM: Boldly Living outdOOrs for Mental Health
Status: RECRUITING
Conditions: Anxiety|Stress Disorder, Posttraumatic|Loneliness|Adverse Childhood Experiences
Interventions: BEHAVIORAL: Group Nature Outings|BEHAVIORAL: Family Outings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Unresectable Hepatocellular Carcinoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 Gozetotide|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Suicide With Safe Alternatives for Teens and Youths (SAFETY)
Status: RECRUITING
Conditions: Suicide and Self-harm
Interventions: BEHAVIORAL: Safe Alternatives for Teens and Youths (SAFETY)|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy
Status: COMPLETED
Conditions: Craniopharyngiomas|Hypothalamic Obesity
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Image-guided Lymphadanectomy in AMIGO
Status: UNKNOWN
Conditions: Lymphadenopathy Retroperitoneal|Lymphoma
Interventions: DEVICE: Image-guided Lymphadanectomy in AMIGO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Non-resectable|Tumor Pancreas|Pain Cancer
Interventions: PROCEDURE: EUS-guided coeliac ganglion neurolysis / celiac plexus neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medihoney® Derma Cream Treatment for Mild to Moderate Atopic Dermatitis in Children Study
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Medihoney Derma Cream|DRUG: Hydrocortisone 1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Stent Modified With 3D Printing for Gastro-respiratory Fistula Involving Carina and Distal Bronchi
Status: UNKNOWN
Conditions: Airway Disease|Fistula Bronchial|Fistula, Gastric
Interventions: PROCEDURE: Airway stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency Evaluation of Intradiploic Intra-osseus Anesthesia Versus Inferior Alveolar Nerve Block
Status: COMPLETED
Conditions: Dental Pain
Interventions: PROCEDURE: Dental anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photodynamic Therapy in Treating Patients With Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Large Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage 0 Non-small Cell Lung Cancer
Interventions: DRUG: HPPH|DRUG: photodynamic therapy|PROCEDURE: therapeutic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Find Out How Well Different Doses of BI 764122 Are Tolerated and Whether Food Affects the Amount of BI 764122 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 764122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reduced-Intensity Preparative Regimen for Allogeneic Stem Cell Transplantation in Patients With Severe Aplastic Anemia
Status: WITHDRAWN
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Cyclophosphamide, Fludarabine, Rabbit ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AR-12 (2-Amino-N-[4-[5-(2 Phenanthrenyl)-3-(Trifluoromethyl)-1H-pyrazol-1-yl] Phenyl]-Acetamide) in Adult Patients With Advanced or Recurrent Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Solid Tumors|Lymphoma
Interventions: DRUG: AR-12: (2-Amino-N-[4-[5-(2 phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] phenyl]-acetamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Integrated Online Program Using Psychoeducation and Expressive Writing for People With Probable Post-traumatic Stress Disorder and Coexisting Dissociative Symptoms
Status: NOT_YET_RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: An integrated online program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Research on New Regimens for Retreatment Pulmonary Tuberculosis
Status: UNKNOWN
Conditions: Reinfection Pulmonary Tuberculosis
Interventions: DRUG: Isoniazid Aminosalicylate Tablets|DRUG: Streptomycin injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GZR18 Injection in Chinese Adult Patients With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: GZR18|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Circumference and Cardiorespiratory Repercussions in Patients Submitted to Physical Therapy
Status: COMPLETED
Conditions: Obesity, Abdominal|Lung Disease
Interventions: OTHER: Chest physiotherapy chest wall expansion|OTHER: Chest physiotherapy airway clearance modality
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema
Status: TERMINATED
Conditions: Cystoid Macular Edema
Interventions: DRUG: Pegaptanib Sodium|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Locally Advanced Irresectable Cancer Ablation
Status: UNKNOWN
Conditions: Locally Advanced Pancreatic Cancer
Interventions: PROCEDURE: Radiofrequency ablation (RFA)|DRUG: FOLFIRINOX|DRUG: Nab-paclitaxel plus Gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria
Status: COMPLETED
Conditions: Malaria in Pregnancy
Interventions: DRUG: Dihydroartemisinin-piperaquine|DRUG: Artesunate-mefloquine|DRUG: Artesunate-amodiaquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Dietary Counseling to Prevent Early Consumption of Added Sugar and Ultra-processed Foods
Status: COMPLETED
Conditions: Infant Nutrition Disorders|Feeding Patterns|Health Knowledge, Attitudes, Practice
Interventions: OTHER: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies
Status: RECRUITING
Conditions: Rapid Eye Movement Sleep Behavior Disorder|Synucleinopathy
Interventions: DRUG: Idebenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combined Anticoagulation and Antithrombotic Therapy vs Antithrombotic Therapy Alone After Lower Extremity Revascularization for Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Combined Anticoagulation and Antithrombotic Therapy|PAD - Peripheral Arterial Disease
Interventions: DRUG: Rivaroxaban 10 MG Oral Tablet [Xarelto]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt
Status: NOT_YET_RECRUITING
Conditions: Bronchial Asthma|Adherence, Medication
Interventions: BEHAVIORAL: the Medisafe android application (https://www.medisafe.com).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prefrontal iTBS on Working Memory
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Transcranial magnetic stimulation (TMS)-active|DEVICE: Transcranial magnetic stimulation (TMS)-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface
Status: UNKNOWN
Conditions: Tonsillitis|Tonsillitis Streptococcal
Interventions: DIAGNOSTIC_TEST: throat culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Orthodontic Tooth Movement|Apnea|Sleep Disordered Breathing
Interventions: OTHER: Medibyte Portable Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of AdCLD-CoV19-1 OMI as a Booster: A SARS-CoV-2 (COVID-19) Preventive Vaccine
Status: COMPLETED
Conditions: COVID-19|Vaccines
Interventions: BIOLOGICAL: AdCLD-CoV19-1 OMI (Part A)|BIOLOGICAL: AdCLD-CoV19-1 OMI (Part B)|OTHER: Placebo (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of CB-03-01 Solution, a Comparator Solution and Vehicle Solution in Males With Androgenetic Alopecia
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: CB-03-01 solution|DRUG: Minoxidil Solution 5%|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abatacept in Individuals Who aRe Considered At Risk of Developing Inflammatory Arthritis
Status: UNKNOWN
Conditions: Inflammatory Arthritis
Interventions: DRUG: Orencia 125 MG Per 1 ML Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Human TH-SC01 Cell Injection for Treating Perianal Fistulas in Patients With Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Perianal Fistula|Crohn's Disease
Interventions: DRUG: Human TH-SC01 cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbiological Efficacy of Systemic Ayurvedic Immunomodulator Septilin in the Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Scaling and root planing, and Septilin for 7 days|DRUG: Scaling and root planing, and Placebo drug for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor vs. Prasugrel Effects on Infarct Size
Status: WITHDRAWN
Conditions: Cardiovascular Disease
Interventions: DRUG: ticagrelor|DRUG: prasugrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Nitazoxanide, Peginterferon Alfa-2a and Ribavirin in Treatment-Naive Hepatitis C Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Nitazoxanide|DRUG: Placebo|BIOLOGICAL: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD)
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Home based body weight type exercises with blood flow restriction|OTHER: Home based body weight type exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Treatment of Hypertension Associated With Severe Preeclampsia (PE). A Trial of Urapidil Versus Nicardipine
Status: TERMINATED
Conditions: Hypertension|Preeclampsia
Interventions: DRUG: Urapidil|DRUG: Nicardipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Spinal Control During Functional Activities to Improve Low Back Pain Outcomes
Status: COMPLETED
Conditions: Mechanical Low Back Pain|Chronic Low Back Pain
Interventions: BEHAVIORAL: Motor skill training|BEHAVIORAL: Strength and flexibility exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Care and Treatment for Severe Infectious Diseases and Substance Use Disorders Among Hospitalized Patients
Status: RECRUITING
Conditions: Injection Site Infection|Substance Use Disorders
Interventions: BEHAVIORAL: SIRI Team|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder?
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: OTHER: nurse semi-structured interview|OTHER: Music & Relaxation with eyes closed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation/Temozolomide and Immunotherapy With Daratumumab to Improve Antitumor Efficacy in Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Mechanism of a Probiotic Combination VSL#3 in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
Status: COMPLETED
Conditions: Rhinoplasty|Dexmedetomidine|Remifentanil
Interventions: DRUG: Remifentanil 2 MG|DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The AVB Study: Prospective Study Comparing the Ahmed Valve and the Baerveldt Implant for Treating Refractory Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Ahmed FP7 Valve|DEVICE: Baerveldt-350 Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Macronutrients in the Diet on Digestive and Cardiovascular Health
Status: COMPLETED
Conditions: Obesity|Diabetes|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Olive oil|DIETARY_SUPPLEMENT: Olive oil and fish powder|DIETARY_SUPPLEMENT: Olive oil and macadamia oil|DIETARY_SUPPLEMENT: Deadaptation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare the Efficacy and Safety of CELBESTA® and CELEBREX® in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CELBESTA®|DRUG: CELEBREX®|DRUG: CELEBREX® placebo|DRUG: CELBESTA® placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: PDR001|DRUG: LAG525|DRUG: INC280|DRUG: ACZ885|DRUG: LEE011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: a Pilot Study
Status: COMPLETED
Conditions: Pain|Anxiety|Burns|Child|Injuries
Interventions: DEVICE: VR distraction via Oculus Rift|OTHER: Standard pharmacological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Tumors|Cancer of Breast
Interventions: DRUG: Metformin|DRUG: Atorvastatin|PROCEDURE: Breast surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biochemical Assessment of Ozonated Olive Oil Mixed Bone Substitute in Treating Intra Bony Periodontal Defect
Status: RECRUITING
Conditions: Periodontitis
Interventions: BIOLOGICAL: ozonized olive oil|BIOLOGICAL: xenograft bone substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Donor Selection, Nonmyeloablative BMT for B-cell Lymphomas With Post-transplantation Cy and Rituximab
Status: TERMINATED
Conditions: Lymphoma|B-cell Lymphoma|Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total body irradiation|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Rituximab|BIOLOGICAL: Allogeneic Bone Marrow Transplant (BMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Use of a Novel Cardioplegic Formula With MPS ® Using the MiECC in Isolated CABG Versus OPCABG
Status: COMPLETED
Conditions: Complication of Coronary Artery Bypass Graft|Complication of Extracorporeal Circulation
Interventions: PROCEDURE: CABG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Depression in Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Depression in Parkinson's Disease
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Syndrome After Oropharyngeal Cancer Treatment
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome|Oropharyngeal Cancer
Interventions: PROCEDURE: Surgery|RADIATION: Radio- chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Atropine for Preventing Ventilator-Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator-Associated Pneumonia
Interventions: DRUG: Atropine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis
Status: RECRUITING
Conditions: Periodontitis Chronic Generalized Moderate|Periodontitis Chronic Generalized Severe
Interventions: DEVICE: Lumoral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of Otomycosis
Status: COMPLETED
Conditions: Otomycosis
Interventions: DRUG: G238|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ProStat Supplementation in Dialysis Patients
Status: TERMINATED
Conditions: Malnutrition|ESRD
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement ProStat 64 twice a day|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VGX-100 Administered Alone and Co-administered With Bevacizumab in Adult Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Cancer
Interventions: DRUG: VGX-100|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of SYN-010 on Subjects With IBS-C
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: SYN-010 21 mg|DRUG: SYN-010 42 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Determine the Safety and Efficacy of Replacement Factor VIII Protein (Known as rFVIIIFc) in Previously Untreated Males With Severe Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: rFVIIIFc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Restricted Feeding on Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Time restricted feeding|BEHAVIORAL: Continuous Energy Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Relation Between Lipid Myocardial Overload Evaluated by Cardiac Magnetic Resonance Imaging (MRI), Alteration of Longitudinal Myocardial Deformations by Echocardiography, and Clinical Achievements (Functional, Biological and Electrical) in Fabry Disease, and Its Outcomes.
Status: UNKNOWN
Conditions: Fabry Disease
Interventions: DIAGNOSTIC_TEST: Echocardiography at T0|DIAGNOSTIC_TEST: Exercise test|BIOLOGICAL: Biological assays|DEVICE: MRI with contrast agent injection|DEVICE: MRI without contrast agent injection|DIAGNOSTIC_TEST: Echocardiography at M24
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Consuming Beans for One Month on Blood Lipids, Satiety, Intake Regulation and Body Weight
Status: COMPLETED
Conditions: Overweight|Obesity|Metabolic Syndrome|Diabetes|Hypertension
Interventions: OTHER: navy beans added to regular diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pediatric Rehabilitation for Children With Cerebral Palsy Through PVT Using AI to Reduce Spasticity
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy
Interventions: DIAGNOSTIC_TEST: Personalized vibration therapy powered by AI|OTHER: Physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CKD-11101 Phase 3 SC Study
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: BIOLOGICAL: CKD-11101(Darbepoetin alfa)|BIOLOGICAL: NESP(Darbepoetin alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke
Status: NOT_YET_RECRUITING
Conditions: Critical Care|Hyperchloremia|Hemorrhagic Stroke
Interventions: DRUG: Multiple Electrolyte|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Models of Care in the Transition From the Secondary to the Primary Sector Among the Frailest Elderly
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Transitional Care|Frailty|Readmission|Aging|Elderly
Interventions: OTHER: Early follow-up visit after discharge|OTHER: Comprehensive geriatric assessment (CGA)|OTHER: Continued geriatric care|OTHER: Possible follow-up visit from GP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supplementation With PUFA´s in Obese Children
Status: COMPLETED
Conditions: Child Obesity|Insulin Resistance|Metabolic Complication
Interventions: DIETARY_SUPPLEMENT: AGPI ω-3 (Triple Strength Fish Oil®)|DIETARY_SUPPLEMENT: AGPI ω-3 + MUFA (avocado oil)|DIETARY_SUPPLEMENT: MUFA (avocado oil) (1.8g)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Health Staff
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: DRUG: Music intervention|DRUG: Nicotine replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AVANDIA With Glyburide In African American And Hispanic Patients With Type 2 Diabetes Not Controlled by Glyburide Alone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT