pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study Examining The Effect Of Renal Impairment On Safety, Toleration And How The Body Processes An Experimental Drug
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: CP-945,598|DRUG: CP-945,598
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat Plus Ifosfamide, Carboplatin, and Etoposide (ICE) Compared With ICE For Relapsed Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Panobinostat|DRUG: Ifosfamide|DRUG: Mesna|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MK-8457 100 mg|DRUG: Methotrexate|DRUG: Dose-match placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of GSK2330811 in Healthy Subjects
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DRUG: GSK2330811|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy of Laying a Biliary Stent for Producing a Heavy Chemotherapy in Unresectable Pancreatic Adenocarcinomas
Status: COMPLETED
Conditions: Adenocarcinoma of Head of Pancreas
Interventions: DEVICE: Type WallFlex or Evolution biliary, stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate Efficacy and Safety of a Single Injection of GenSci094 for Ovarian Stimulation Using Daily Recombinant FSH as Reference
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: GenSci094|DRUG: Placebo RecFSH / follitropin alfa|BIOLOGICAL: Biological: RecFSH / Follitropin alfa (Days 1 to 7)|DRUG: Placebo GenSci094|BIOLOGICAL: RecFSH / Follitropin alfa (Days 8 to hCG)|DRUG: Ganirelix|BIOLOGICAL: hCG|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Exercise-induced Pulmonary Arterial Hypertension
Interventions: DRUG: Ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IBI351 in Combination With Cetuximab in Subjects With KRAS G12C Mutated Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: IBI351|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis
Status: NOT_YET_RECRUITING
Conditions: Drug-resistant Tuberculosis|HIV Coinfection|Cost-Benefit Analysis
Interventions: DIAGNOSTIC_TEST: Targeted next-generation sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Intervention With Therapeutic Exercise in Plantar Fasciopathy
Status: NOT_YET_RECRUITING
Conditions: Plantar Fascitis
Interventions: OTHER: Muscle strengthening|DRUG: Standard treatment (oral analgesic/anti-inflammatory drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Survival After Ischaemic Stroke: Ebrictus Study
Status: COMPLETED
Conditions: Ischemic Stroke|Thrombolytic (t-PA) Treatment|Gender Bias|Long Term Adverse Effects
Interventions: DRUG: IV thrombolytic (t-PA) treatment vs not
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Apremilast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Multidisciplinary and Radiologic Review on Outcome of Pancreatic Cancer Patients: an Observational Study
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: application of a diagnostic and therapeutic protocol (multidisciplinary discussion and radiological CT review)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Intravenous Administration of ICVB-1042
Status: RECRUITING
Conditions: Patients With Advanced Solid Tumors
Interventions: DRUG: Treatment with ICVB-1042 administered intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Boost and Long-Term Androgen Deprivation for Adenocarcinoma of the Prostate
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate
Interventions: RADIATION: Stereotactic Radiosurgical Boost|DRUG: Casodex|DRUG: Leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)
Status: SUSPENDED
Conditions: Cardiac Resynchronization Therapy|Magnetic Resonance Imaging (MRI)
Interventions: PROCEDURE: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Oracea and Epiduo Forte in Severe Acne Patients
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Doxycycline Anhydrous 40 MG|DRUG: Adapalene/Benzoyl Peroxide Gel 0.3-2.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, PK and PD of GSK2339345 in Healthy Subjects
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: GSK2339345 (solution)|DRUG: GSK2339345 (nebulised)|DRUG: Placebo (0.9% sodium chloride solution)|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease
Status: RECRUITING
Conditions: Haemorrhoids|Internal Haemorrhoids|Grade II/III Haemorrhoids
Interventions: PROCEDURE: Doppler-Guided Haemorrhoidal Artery Ligation|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microcurrent Stimulation for Dry Age-related Macular Degeneration
Status: WITHDRAWN
Conditions: Dry Age-related Macular Degeneration
Interventions: DEVICE: i-Lumen AMD|DEVICE: i-Lumen AMD Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Laparoscopic Techniques for Management of Congenital Inguinal Hernia in Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Congenital Inguinal Hernia
Interventions: PROCEDURE: Laparoscopic assisted hernia|PROCEDURE: Laparoscopic hernia by purse string closure|PROCEDURE: Total laparoscopic dissection of hernial sac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Temsirolimus, Erlotinib and Cisplatin in Solid Tumors
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Temsirolimus|DRUG: Cisplatin|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bladder Stimulation Technique on Urine Specimen Collection in Newborns
Status: COMPLETED
Conditions: Urine Specimen Collection
Interventions: PROCEDURE: The bladder stimulation technique|PROCEDURE: Steril urine bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adjuvant Treatment Deintensification After Transoral Surgery for Human Papillomavirus-Positive Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Oropharynx|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: 44 doses of radiation|RADIATION: 54 doses of radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium|Post-cardiac Surgery
Interventions: OTHER: Limited Intraoperative Benzodiazepine|OTHER: Liberal Intraoperative Benzodiazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Rimonabant Efficacy in Insulin-Treated Diabetic Patients(ARPEGGIO)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Rimonabant (SR141716)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectum Cancer
Interventions: DEVICE: Parietene Macro|DEVICE: Permacol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effects of Different Interventions on Glycemic Control in Newly-Diagnosed Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Human Insulin (Novolin-R, Novo Nordisk)|DEVICE: H-Tron Plus V100; Disetronic Medical System, Burgdorf, Switzerland|OTHER: Pre-meal|DRUG: Novolin-R|DRUG: Human Insulin NPH (Novolin-N, Novo Nordisk)|DRUG: Gliclazide (Diamicron, Servier)|DRUG: Diamicron and Glucophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus
Status: UNKNOWN
Conditions: Esophageal Cancer|Precancerous Condition
Interventions: OTHER: questionnaire administration|PROCEDURE: comparison of screening methods|PROCEDURE: diagnostic endoscopic procedure|PROCEDURE: esophagogastroduodenoscopy|PROCEDURE: tethered capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Different Microprocessor Knee Prostheses on Mobility and Gait Parameters in Transfemoral Amputees
Status: UNKNOWN
Conditions: Amputation
Interventions: OTHER: questionnaires for clinical assessments|OTHER: 2 minute walking test|OTHER: The gait analysis at the motion analysis laboratory.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Progesterone on Smoked Nicotine Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effects
Status: SUSPENDED
Conditions: Nicotine Dependence
Interventions: OTHER: Nicotine|OTHER: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Erector Spinae Plane Blocks (ESP) for Postoperative Pain in Lumbo-sacral Spine Surgery
Status: UNKNOWN
Conditions: Erector Spinae Plane Block|Lumbar Spine Surgery
Interventions: PROCEDURE: Bilateral lumbar erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of D-allulose Consumption on Postprandial Glycaemia
Status: COMPLETED
Conditions: Sugar; Blood, High
Interventions: OTHER: D-Allulose|OTHER: Sodium Saccharin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study to Evaluate Safety and Efficacy of CB-103 With Venetoclax in Adolescent and Young Adult Patients With Relapsed/Refractory T-ALL or T-LBL
Status: TERMINATED
Conditions: Leukemia, Lymphoblastic|Leukemia
Interventions: DRUG: CB-103|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting Patients With Myofascial Temporomandibular Disorders
Status: COMPLETED
Conditions: Myofascial Temporomandibular Disorder|Bruxism, Sleep|Sleep Disturbance|Jaw Spasm|Headache
Interventions: OTHER: Scales and indexes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pericapsular Nerve Group (PENG) Block Versus Periarticular Injection for Pain Management After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group block|PROCEDURE: Periarticular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol
Status: COMPLETED
Conditions: Intraoperative Awareness
Interventions: DRUG: Isoproterenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Spectroscopy (NIRS) and Superior Mesenteric Artery (SMA) Doppler Patterns as Predictor of Feeding Tolerance in Very Low Birth Weight (VLBW) IntraUterine Growth Restricted (IUGR) and NON IUGR Infants
Status: COMPLETED
Conditions: Infant, Very Low Birth Weight|Infant Malnutrition|Feeding Disorder of Infancy or Early Childhood|Splanchnic Oximetry|Splanchnic Oxygenation
Interventions: OTHER: different nutrional regimen|OTHER: comparison of different feeding regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease (MK-0431-073 AM1)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|End-Stage Kidney Disease
Interventions: DRUG: Sitagliptin|DRUG: Glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Compare the Efficacy and Safety of the Combination of Etanercept and Methotrexate in Treatment of Rheumatoid Arthritis
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept + Methotrexate|DRUG: DMARDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency
Status: UNKNOWN
Conditions: Crohn's Disease|Vitamin D Deficiency|Vitamin D Supplement
Interventions: DRUG: Caltrate Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Combination With Liposomal Doxorubicin and Dexamethasone to Treat Plasma Cell Leukemia
Status: UNKNOWN
Conditions: Plasma Cell Leukemia|Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Liposome doxorubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The NUTRIENT Trial (NUTRitional Intervention Among myEloproliferative Neoplasms): Feasibility Phase
Status: COMPLETED
Conditions: Myeloproliferative Disorder|Myeloproliferative Syndrome|Myelofibrosis|Polycythemia Vera|Essential Thrombocythemia
Interventions: OTHER: USDA Diet|OTHER: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
Status: ENROLLING_BY_INVITATION
Conditions: HIV|Hepatitis B|Hepatitis C|AIDS|Coinfection|Cardiovascular Diseases|Diabetes Mellitus|Acidosis, Lactic|Renal Insufficiency|Fractures, Bone|End Stage Liver Disease|Kidney Failure, Chronic|Proteinuria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Family-Centered Pediatric Trauma Care: The Standard of Care Versus the Virtual Pediatric Trauma Center
Status: ACTIVE_NOT_RECRUITING
Conditions: Trauma|Injuries
Interventions: OTHER: Virtual Pediatric Trauma Center
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Strategy of "Pulmonary Opening by Titration of Positive End-expiratory Pressure" Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients?
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: OTHER: TITRATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Kron (Citicoline and Nicotinamide Oral Solution) on Patients With Open-angle Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Glaucoma
Interventions: OTHER: Food for Special Medical Purposes: Kron®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants
Status: TERMINATED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Cotadutide|DRUG: Cotadutide-placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative|Inflammatory Bowel Diseases
Interventions: DRUG: Placebo IV|DRUG: Placebo SC|DRUG: Ustekinumab IV|DRUG: Ustekinumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Procalcitonin To Reduce Antibiotics in Chronic Obstructive Lung Disease (ProToCOLD)
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease
Interventions: OTHER: Discontinuation of Antibiotcs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AZD2693|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: SODIUM CHLORIDE|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine
Status: COMPLETED
Conditions: Familial Hemiplegic Migraine
Interventions: DRUG: Nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706
Status: TERMINATED
Conditions: Early Parkinson Disease
Interventions: DRUG: K0706|DRUG: K0706|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epigenetics Modifications in Morbid Obesity and Obstructive Sleep Apnea Patients: The EPIMOOSA Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Morbid Obesity|Epigenetic Disorder
Interventions: DEVICE: CPAP|PROCEDURE: Bariatric Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Direct Stimulation in Chronic Pelvic Pain
Status: COMPLETED
Conditions: Pelvic Pain|Healthy
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and B
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole group|DRUG: Dexlansoprazole group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic ablative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Diagnostic Ultrasound in the Detection and Therapy of Acute Coronary Syndromes
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome|Myocardial Infarction
Interventions: DEVICE: Use of intermittent high MI impulses during echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Versus Conventional Full-arch Implant Impression in Maxillary Screw- Retained Implant Prosthesis
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: DEVICE: Maxillary screw-retained prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microvention AnEurysm & STroke Real-life Data cOllection
Status: NOT_YET_RECRUITING
Conditions: Intracranial Aneurysm|Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm, Lesion|Aneurysmal Subarachnoid Hemorrhage
Interventions: DEVICE: All Microvention Class III implantable device CE marked
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Outcome of Corticosteroids in Transforaminal Endoscopic Lumbar Discectomy
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: 40 mg Triamcinolone acetate 1 cc|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pre-Operative Chemotherapy in Patients With Resectable Local-Regional Carcinoma of Esophagus
Status: TERMINATED
Conditions: Esophageal Diseases
Interventions: DRUG: Taxol, Cisplatin, 5-Fluorouracil, G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries
Status: RECRUITING
Conditions: Syndesmotic Injuries
Interventions: DEVICE: Arthrex Tightrope|DEVICE: Synthes Fibulink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Cerenkov Luminescence Imaging of Lymphoma, Leukemia and Metastatic Lymph Nodes
Status: COMPLETED
Conditions: Head and Neck Cancers
Interventions: RADIATION: Cerenkov emissions from the PET tracer 18F-FDG and the radiotherapeutic 131I
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterisation of the Intratumoral Microbiome in Gastric Adenocarcinoma: to a Personalised Medicine
Status: RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: PROCEDURE: Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial Designed To Evaluate The Safety And Exploratory Efficacy Of 1.0 Mg Luminate® (Alg-1001) As A Treatment For Non-Exudative Macular Degeneration
Status: COMPLETED
Conditions: Dry Age-related Macular Degeneration
Interventions: DRUG: Risuteganib|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Internal Radiation Therapy (SIRT) in Patients With Unresectable Colorectal Cancer Liver Metastases Who Failed Prior Intraarterial Pump Chemotherapy
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer
Interventions: DEVICE: SIR-spheres® (Selective Internal Radiation Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hot Snare Versus Hot Snare Polypectomy With Saline Injection for Colorectal Polyps
Status: COMPLETED
Conditions: Polyp of Large Intestine
Interventions: PROCEDURE: hot snare polypectomy|PROCEDURE: hot snare polypectomy after saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Ixabepilone Administered as a 24 Hour Infusion in Patients With Solid Malignancies.
Status: COMPLETED
Conditions: Solid Malignancies
Interventions: DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Diffuse Large B-cell Lymphoma of the Central Nervous System (CNS)|Aggressive B-cell Lymphoma With Secondary Involvement of the CNS
Interventions: DRUG: Obinutuzumab|DRUG: Prednisone|DRUG: Lenalidomide|DRUG: Venetoclax|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Shoulder Tip Pain Following Laparoscopic Surgery
Status: UNKNOWN
Conditions: Shoulder Pain|Laparoscopic Surgery
Interventions: PROCEDURE: Pulmonary recruitment maneuver|PROCEDURE: Intraperitoneal normal saline|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of ARRY-334543 and Capecitabine in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: ARRY-334543, EGFR/ErbB2 inhibitor; oral|DRUG: Capecitabine, 5-fluorouracil prodrug; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Efficacy of HB0034 in Subjects With Generalized Pustular Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: HB0034
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Diagnostic Accuracy Study Testing Fecal Biomarkers In Comparison To Endoscopic Examination
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Testing Fecal Biomarkers In Comparison To Endoscopic Examination With Confocal Laser Endomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection
Status: TERMINATED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: ARC-520|DRUG: Placebo|DRUG: entecavir|DRUG: chlorpheniramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigator-blind Multi-center Prospective Study for the Efficacy and Safety of Silicon Gel (Dermatix)
Status: UNKNOWN
Conditions: Hypertrophic Cicatrix
Interventions: DEVICE: silicone gel|OTHER: no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Patritumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Protocol of 68Ga PSMA 11 PET Imaging of Prostate Cancer
Status: APPROVED_FOR_MARKETING
Conditions: Prostatic Neoplasms|Prostatic Diseases|Prostate Cancer|Prostate Cancer Metastatic|Prostate Cancer Recurrent
Interventions: DRUG: 68GA PSMA-HBED-CC
Study Type: EXPANDED_ACCESS
Clinical trial: Impact of Providing Free Preventive Dental Health Products on Infant's Tooth Brushing and Bottle-feeding Termination Practices
Status: COMPLETED
Conditions: Infant's Tooth Brushing
Interventions: OTHER: Infant oral health promotion package|OTHER: Infant oral health pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of 2 Doses of Corticosteroid Subacromial Injections for the Treatment of Painful Shoulder
Status: WITHDRAWN
Conditions: Tendonitis|Bursitis
Interventions: DRUG: Betamethasone Sodium Phosphate|DRUG: 1 cc - Betamethasone Sodium Phosphate|DRUG: 2 cc - Betamethasone Sodium Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic Drug
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Metastatic Colon/Rectum Cancer|Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: [F-18]RGD-K5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Soy Isoflavone Supplementation on Endothelial Function
Status: COMPLETED
Conditions: Cardiovascular Disease|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: soy isoflavone|DIETARY_SUPPLEMENT: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia With Gene Mutations|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Therapy-Related Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Bone Marrow Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Natural Killer Cell Therapy|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Multicentre Evaluating the Effectiveness and Toxicity Sorafenib (Nexavar®) in Adult Patients With Uveal Melanoma and Metastatic Dissemination
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DRUG: Sorafenib at a dose of 800 mg / day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Central Memory Cells in Early Localized Non-Segmental Vitiligo
Status: NOT_YET_RECRUITING
Conditions: Vitiligo
Interventions: DRUG: oral mini pulse|DRUG: Topical cream|DEVICE: targeted phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: amsacrine|DRUG: asparaginase|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|DRUG: therapeutic hydrocortisone|PROCEDURE: allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sorafenib With BIIB022 in Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: BIIB022|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors
Status: UNKNOWN
Conditions: Recurrent or Refractory Solid Tumors|Ewing Sarcoma|Rhabdomyosarcoma|Neuroblastoma|Osteosarcoma
Interventions: DRUG: MM-398 (Irinotecan Sucrosofate Liposome Injection) plus cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filgotinib Versus Placebo in Adults With Active Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Biologic Disease-modifying Anti-rheumatic Drug(s) (DMARDs) Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Filgotinib|DRUG: Placebo to match filgotinib|DRUG: csDMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Thymoglobulin|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Fortification of Complementary Foods in Bihar India
Status: COMPLETED
Conditions: Anemia|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Home Fortification Product (HFP)|OTHER: Infant and Young Child Feeding (IYCF) Practices Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Tomato-Soy Juice on Biomarkers in Patients With Prostate Cancer Undergoing Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: tomato-soy juice|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral PG-116800 Following a Heart Attack
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Failure|Heart Enlargement
Interventions: DRUG: PG-116800 (given as PG-530742)|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: TV-45070|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Blood-Oxygen-Level-Dependent (BOLD) Signal Changes in the Brain by Paracetamol as Measured by Functional Magnetic Resonance Imaging (fMRI) in Subjects With Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addition of MgSO4 or Dexamethasone to Bupivacaine on the Prolongation of Ultrasound-guided Quadratus Lumboram Block
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Bupivacaine- Magnesium|DRUG: Bupivacaine dexamethasone|DRUG: Bupivacaine saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: FAmily-CEntered Advance Care Planning|BEHAVIORAL: Healthy Living Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Microbiome and Diet in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Diet, Healthy|Gut Microbiome|Gastrointestinal Microbiome
Interventions: OTHER: Mediterranean-style diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Gemcitabine With or Without Panitumumab in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: erlotinib hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMRT Plus Cisplatin Versus IMRT in Patients With Stage 2 Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Intensity modulated radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Remineralizing Products Used in Molar Grooves: Evaluation With Diagnodent Pen and Diagnocam
Status: ENROLLING_BY_INVITATION
Conditions: Enamel Caries
Interventions: OTHER: Home use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate Light-induced Skin Reactions After Application of Delgocitinib Cream
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Delgocitinib cream|DRUG: Delgocitinib cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor-positive Breast Cancer|Musculoskeletal Complications|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: anastrozole|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Clomiphene Citrate Ovulation Induction on Frozen Embryo Transfer
Status: UNKNOWN
Conditions: Infertility, Female|Clomiphene Citrate
Interventions: DRUG: Clomiphene Citrate protocol|PROCEDURE: Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Using Dextrose-containing Intraoperative Fluid in Children
Status: UNKNOWN
Conditions: Pediatric Surgery
Interventions: DRUG: Ringer acetate|DRUG: 1.25%Dextrose equivalence|DRUG: 2.5%Dextrose equivalence|DRUG: Dextrose 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation-Based Action Observation Treatment in Children With Hemiparetic Cerebral Palsy
Status: UNKNOWN
Conditions: Hemiparetic Cerebral Palsy
Interventions: OTHER: Synchronous telerehabilitation group|OTHER: Asynchronous telerehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Disconnection Technique With a Bronchial Blocker for Improving Lung Deflation
Status: COMPLETED
Conditions: Pneumothorax
Interventions: PROCEDURE: DLT with conventional technique|PROCEDURE: BB with conventional technique|PROCEDURE: Disconnection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Etrumadenant|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus 1-min Oscillometric Arterial BP Monitoring
Status: RECRUITING
Conditions: Anesthesia, General
Interventions: DEVICE: 1-min interval oscillometric method|DEVICE: arterial catheterization method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Assessing the Efficacy of Chidamide for CD30-positive Peripheral T-cell Lymphoma (PTCL).
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Fosfomycin in the Treatment of Complicated Urinary in Real-life Conditions.
Status: UNKNOWN
Conditions: Complicated Urinary Tract Infection
Interventions: OTHER: Drug: Intravenous fosfomycin|OTHER: Drug: Intravenous quinolone or beta-lactam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nurse Smoking Cessation of Patients With Chronic Obstructive Pulmonary Disease (COPD) With Nicotine Replacement Therapy (NRT) and Behavioral Support
Status: TERMINATED
Conditions: Smoking|COPD
Interventions: DRUG: nicotine sublingual tablets|BEHAVIORAL: low and high behavior support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT