pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Online Pilates in Individuals With Chronic Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Chronic Pain
Interventions: OTHER: Pilates method|OTHER: Pain education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|B-cell Non Hodgkin Lymphoma|Pre B-Cell Acute Lymphoblastic Leukaemia
Interventions: DRUG: Blinatumomab 9ug|DRUG: Blinatumomab 28 ug|DRUG: Blinatumomab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIETary Intake, Death and Hospitalization in Adult With End-stage Kidney Disease Treated With HemoDialysis (DIET-HD) Study
Status: COMPLETED
Conditions: Diet Habit|End Stage Renal Disease
Interventions: OTHER: dietary intake of omega-3 and omega-6 polyunsaturated fatty acids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cefixime Plus Doxycycline Compared to Ceftriaxone Plus Azithromycin for Treatment of Gonorrhoea
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: Cefixime|DRUG: Doxycyclin|DRUG: Ceftriaxon|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Recombinant Flagellin Subunit Campylobacter Vaccine (rFla-MBP) Dose-Ranging Study
Status: WITHDRAWN
Conditions: Diarrhea
Interventions: BIOLOGICAL: rFla-MBP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterizing Sleep Disorders in Children and Adults With Tuberous Sclerosis Complex (TSC)
Status: UNKNOWN
Conditions: Sleep Disorder
Interventions: OTHER: Questionnaires|PROCEDURE: electroencephalogram (EEG)|PROCEDURE: polysomnography|PROCEDURE: Actigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults
Status: RECRUITING
Conditions: Homocysteine
Interventions: DIETARY_SUPPLEMENT: supplementation of compound nutrients|DIETARY_SUPPLEMENT: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Ovarian Stimulation for Assisted Reproduction With Two Different Forms of Pituitary Suppression
Status: COMPLETED
Conditions: Female Infertility Due to Nonimplantation of Ovum|Complications Associated With Artificial Fertilization
Interventions: DRUG: Pergoveris in long protocol with GnRH agonist|DRUG: Pergoveris in GnRH antagonist protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation
Status: COMPLETED
Conditions: AMD
Interventions: DRUG: Vitamin A palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time Margin Assessment in Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: PROCEDURE: Fluorescence guided detection of tumor positive margins|DRUG: Cetuximab-IRDye800
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hybrid Simulation Method on Advanced Life Support Application of Nursing Students
Status: RECRUITING
Conditions: Advanced Life Support|Simulation Training|Nursing Education
Interventions: OTHER: Advanced life support training with high reality simulator|OTHER: Advanced life support training with web-based simulation|OTHER: Advanced life support training with hybrid simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure|Sleep Disordered Breathing|COPD|Obesity Hypoventilation Syndrome (OHS)
Interventions: DEVICE: Remote monitoring of home mechanical ventilation (NIV) using SRETT|OTHER: Home mechanical ventilation (NIV) without remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaysian COVID-19 Anosmia Study (Phase 1) - A Nationwide Multicentre Cross-Sectional Study
Status: COMPLETED
Conditions: SARS-CoV Infection|COVID-19|Anosmia|Dysgeusia
Interventions: OTHER: Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cimex Lectularius or Bed Bugs : Vector of Infectious Agents and Pathogenic Role
Status: COMPLETED
Conditions: Sting
Interventions: OTHER: Collection of the bedbugs and dermatological follow-up of the stings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: CD19 CAR-T|DRUG: CD22 CAR-T|DRUG: CD 19+22|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Curcumin and Pentoxiphylline on Chronic Kidney Disease Patients
Status: RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Curcumin|DRUG: Pentoxifylline 400 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BEHAVIORAL: higher fat, high polyunsaturated fat diet|BEHAVIORAL: higher fat, high saturated and trans fat diet|BEHAVIORAL: lower fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Isotretinoin, Silymarin and Both in the Treatment of Acne Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Isotretinoin ,silymarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CALM for Pregnant and Post-Partum Women
Status: WITHDRAWN
Conditions: Anxiety|Depression|Depression, Postpartum|Pregnancy Related|CBT
Interventions: BEHAVIORAL: Coordinated Anxiety Learning and Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Claudication|Claudication, Intermittent|Vascular Occlusion|Vascular Calcification|Vascular Diseases|Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: SPM Emulsion, Dose-modality|DIETARY_SUPPLEMENT: SPM Softgel, Dose-Modality|DIETARY_SUPPLEMENT: Placebo Softgel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study To Investigate Effects Of GSK561679 On Brain Activation During Emotional Processing In Healthy Volunteers
Status: COMPLETED
Conditions: Depressive Disorder and Anxiety Disorders
Interventions: DRUG: single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Proteases in Patients With Prostate Cancer That Has Spread to the Bone
Status: COMPLETED
Conditions: Anemia|Metastatic Cancer|Myelodysplastic Syndromes|Precancerous Condition|Prostate Cancer
Interventions: GENETIC: fluorescence in situ hybridization|GENETIC: microarray analysis|GENETIC: molecular diagnostic method|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|PROCEDURE: immunoscintigraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients
Status: COMPLETED
Conditions: Thalassemia
Interventions: DRUG: curcuminoids, N-acetylcysteine, deferiprone and vitamin E|DRUG: Curcuminoids and alpha-tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of Amniotic Fluid Ferning in the Second Trimester in the Diagnosis of Preterm Prelabor Rupture of Membranes
Status: RECRUITING
Conditions: Preterm Premature Rupture of Membrane|Amniotic Fluid Leakage
Interventions: DIAGNOSTIC_TEST: Ferning on microscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Syndrome of Newborn
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Market Registry for GORE® TAG® Thoracic Branch Endoprosthesis
Status: NOT_YET_RECRUITING
Conditions: Aneurysm|Dissection, Aortic|TAA Thoracoabdominal Aortic Aneurysm|Thoracic Aortic Aneurysm|Transection Aorta
Interventions: DEVICE: GORE® TAG® Thoracic Branch Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dakin's Solution in Preventing Radiation Dermatitis in Patients With Breast Cancer Undergoing Radiation Therapy
Status: COMPLETED
Conditions: Breast Cancer|Skin Reactions Secondary to Radiation Therapy
Interventions: DRUG: Dakin's solution|RADIATION: radiation therapy|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer Stage IV|Invasive Breast Cancer|Ovarian Cancer|Ovarian Cancer Stage 1|Ovarian Cancer Stage II|Ovarian Cancer Stage III|Ovarian Cancer Stage IV|Ovarian Cancer Stage IA|Ovarian Cancer Stage IB|Ovarian Cancer Stage IC|Ovarian Cancer Stage 2|Ovarian Cancer Stage 3|Ovarian Cancer Stage IIIb|Ovarian Cancer Stage IIIC|Breast Cancer Stage IIIA|Breast Cancer Invasive|Breast Cancer, Stage IA|Breast Cancer, Stage IB|Breast Cancer Stage IIA|Breast Cancer Stage IIB|Breast Cancer Stage IIIB|Breast Cancer Stage IIIc|Cancer, Breast|Tumors, Breast|Mammary Cancer|Mammary Carcinoma|Breast Carcinoma|Breast Neoplasm|Malignant Breast Neoplasm|Malignant Tumor of Breast|Cancer of Ovary|Ovary Cancer|Ovary Neoplasm
Interventions: DRUG: Tart Cherry Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Hepatocellular Cancer|Colorectal Cancer|Colorectal Carcinoma|Liver Metastases
Interventions: BIOLOGICAL: Neoantigen Dendritic Cell Vaccine|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib In Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Invasive Breast Cancer|Somatic Mutation Breast Cancer (BRCA1)|Somatic Mutation Breast Cancer (BRCA2)|CHEK2 Gene Mutation|ATM Gene Mutation|PALB2 Gene Mutation|RAD51 Gene Mutation|BRIP1 Gene Mutation|NBN Gene Mutation
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453
Status: COMPLETED
Conditions: Hypertension|Chronic Heart Failure
Interventions: DRUG: BIA 5-453|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Low-Risk Polycythemia Vera
Status: NOT_YET_RECRUITING
Conditions: Polycythemia Vera|Myeloproliferative Neoplasm
Interventions: DRUG: Ropeginterferon alfa-2b|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin + 5-FluoroUracil/LeucoVorin (5-FU/LV) (FOLFOX4) Versus Doxorubicin as Palliative Chemotherapy in Advanced Hepatocellular Carcinoma Patients
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Oxaliplatin + 5-Fluorouracil/Leucovorin|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uncovered Self-expandable Metal Stent Versus Double Layer Plastic Stent for Malignant Hilar Stricture
Status: UNKNOWN
Conditions: Bile Duct Obstruction|Klatskin's Tumor
Interventions: DEVICE: SEMS insertion|DEVICE: DLS insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: DEB-TACE with visualable microspheres|DEVICE: DEB-TACE with PVA microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy Plus Codonopsis Pilosula Nnannf /Placebo
Status: RECRUITING
Conditions: Pancreatic Carcinoma|Adjuvant Chemotherapy|Cancer-related Fatigue
Interventions: DRUG: Codonopsis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Treatment of Moderate-to-severe Psoriasis in Adults: Update of the French Guidelines
Status: UNKNOWN
Conditions: Psoriasis|Psoriasis Palmaris|Psoriasis Inverse|Psoriasis Vulgaris|Psoriatic Nail|Psoriatic Plaque|Psoriasis Guttate|Psoriasis of Scalp|Psoriasis Universalis|Psoriatic Erythroderma|Psoriasis Pustular
Interventions: OTHER: Experts consensus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dates a Food Treasure in Alleviating Anemia
Status: COMPLETED
Conditions: Anemia, Iron Deficiency
Interventions: OTHER: Nutritional Education|OTHER: model nutrition kitchen|OTHER: recipe book|OTHER: Provision of Dates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Based Care for Minority Adolescents With ADHD: Improving Fidelity With Machine Learning-Assisted Supervision and Fidelity Feedback.
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Artificial Intelligence-Assisted Supervision Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Evaluation of a New Aspheric Intraocular Lens.
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Advanced Akreos Adapt in one operated eye.|DEVICE: Akreos Adapt in fellow operated eye.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Acute Pain Management in Patients on Opioid Replacement Therapy
Status: TERMINATED
Conditions: Opioid-use Disorder|Pain, Acute
Interventions: DRUG: HYDROmorphone Injectable Solution|DRUG: Ketamine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI
Status: COMPLETED
Conditions: OSA|SCI/D|Upper Airway Exercise
Interventions: OTHER: UA and RMT|OTHER: Sham exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RES-SAFE (Resorption, Safety, and Efficacy of Absorbable Collagen Membrane)
Status: NOT_YET_RECRUITING
Conditions: Guided Bone Regeneration
Interventions: DEVICE: GBR membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Intracerebral Topotecan for Recurrent Brain Tumors
Status: UNKNOWN
Conditions: Brain Neoplasms, Primary Malignant
Interventions: PROCEDURE: Convection-Enhanced Delivery|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Incidence of Hypersensitivity After Administration of Sugammadex in Healthy Participants (MK-8616-101)
Status: COMPLETED
Conditions: Hypersensitivity|Anaphylaxis
Interventions: DRUG: Sugammadex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alafenamide for HBV Prophylaxis in HBV(-) Liver Transplant Recipients With HBcAb+ Donors
Status: UNKNOWN
Conditions: HBV|Liver Transplant Disorder
Interventions: DRUG: Tenofovir Alafenamide 25 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Project Engage: Oral PrEP Acceptability
Status: COMPLETED
Conditions: Acceptability of Health Care|Adherence, Medication
Interventions: DRUG: emtricitabine/tenofovir alafenamide|DRUG: Emtricitabine / Tenofovir Disoproxil Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of Immunological, Molecular-genetic, Image-based and Microbial Analyzes to Characterize Tumor Response and Control in Patients With Inoperable Stage III NSCLC Treated With Chemoradiotherapy Followed by Consolidation Therapy With Durvalumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Oncology|Biomarker|NSCLC, Stage III|Durvalumab|Chemoradiotherapy
Interventions: OTHER: Non-interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tislelizumab With Chemotherapy or Radiation for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma (TINES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tislelizumab + cisplatin + paclitaxel|DRUG: Tislelizumab + radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Connected Caesarean Section": Creating a Virtual Link Between Mothers and Their Infants to Improve Maternal Childbirth Experience: A Pilot Trial
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Childbirth Experience
Interventions: DEVICE: Head-mounted display
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Handheld Event Related Potential (ERP)/Quantitative Electroencephalography (qEEG) System (COGNISION™) as a Useful Cognitive Biomarker for Alzheimer's Disease.
Status: COMPLETED
Conditions: Memory Disorders|Alzheimer Disease|Dementia|Cognitive Impairment|Frontotemporal Dementia
Interventions: DEVICE: COGNISION™ System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: French Study to Evaluate the Impact of a Cognitive Therapy on Urinary Incontinent Women of All Age's Perineal Settings.
Status: UNKNOWN
Conditions: Urinary Incontinence, Stress|Urinary Incontinence, Urge
Interventions: OTHER: Classical rehabilitation|BEHAVIORAL: Cognitive associated rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in the Regulation of Dai Meridian for Polycystic Ovarian Syndrome Patients With Abdominal Obesity
Status: UNKNOWN
Conditions: Polycystic Ovarian Syndrome|Obesity, Abdominal
Interventions: DEVICE: electroacupuncture|BEHAVIORAL: lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Care Ecosystem Consortium Effectiveness Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Dementia, Vascular|Dementia With Lewy Bodies|Dementia Alzheimers|Frontotemporal Dementia
Interventions: BEHAVIORAL: Care Ecosystem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non Invasive Measurement of the Haemodynamic Parameters and of the Advanced Glycation End Products (AGEs) Levels
Status: COMPLETED
Conditions: Hemodynamic Instability|Skin and Subcutaneous Tissue Disorders
Interventions: DIETARY_SUPPLEMENT: caffeine intake|OTHER: cigarette smoking|OTHER: Caffeine intake and Cigarette smoking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: G-CSF and Erythropoetin in Survival of Patients With Decompensated Liver Disease
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: DRUG: G-CSF+EPO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Smart Watch and App on PAP Adherence in OSA (Watch-OSA)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult|Positive Airway Pressure|Adherence, Treatment|Smart Watch
Interventions: DEVICE: the smart watch and Samsung Health app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bifocal vs Trifocal External Bone Transport by Ilizarov Ring External Fixator in Lower Limbs
Status: UNKNOWN
Conditions: Bone Loss
Interventions: PROCEDURE: Bifocal bone transport.|PROCEDURE: Trifocal bone transport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ga-68 Dolacga to Evaluate Liver Reserve Function in Patients With HCC Before and After Proton Therapy
Status: NOT_YET_RECRUITING
Conditions: Hepatic Carcinoma
Interventions: DRUG: Ga-68 Dolacga Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Manual Therapy in Tension-type Headache
Status: COMPLETED
Conditions: Tension-Type Headache
Interventions: PROCEDURE: manipulation plus exercise|PROCEDURE: suboccipital inhibition plus exercise|PROCEDURE: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Push-Pull-Hold Program on Improving Self-Care in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Push-Pull-Hold Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Strategy to Prevent Oversedation in Intensive Care Patients Under Mechanical Ventilation
Status: COMPLETED
Conditions: ICU Patients Requiring Invasive Mechanical Ventilation
Interventions: PROCEDURE: Clinical Procedure to Prevent Oversedation|PROCEDURE: Usual sedation practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Statins in Children With Type 1 Diabetes and Hypercholesterolemia
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent|Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-cancer Pain and Cognitive Impairment: A Disabling Relationship
Status: TERMINATED
Conditions: Arthritis|Pain|Cognitive Impairment
Interventions: DRUG: long acting oxycodone|DRUG: extra strength acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Obesity and Disease Risk in Japanese Americans
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Atherosclerosis|Hypertension|Obesity|Diabetes Mellitus, Non-insulin Dependent|Hyperinsulinism|Insulin Resistance|Coronary Arteriosclerosis|Diabetes Mellitus|Metabolic Syndrome X
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Moist Wound Therapy|DEVICE: VAC Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm|MPN|Essential Thrombocythemia|Polycythemia Vera|Myelofibrosis
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemie Tots: A Pilot Study to Understand the Effects of Prematurity in Toddlerhood
Status: COMPLETED
Conditions: Preterm Birth|Child Development|Child Behavior
Interventions: DRUG: LCPUFA oil supplement|OTHER: Canola Oil Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence
Status: COMPLETED
Conditions: Alcohol Consumption|Violence, Domestic|Stress, Psychological|Aggression
Interventions: BEHAVIORAL: CBT Text Messaging|BEHAVIORAL: Attention Control Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Probiotic Use After Childbirth in Relation to Emotional Well-Being
Status: COMPLETED
Conditions: Mental Health Wellness
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness and Safety of an Early Mobilization Protocol in a Pediatric Intensive Care Unit
Status: RECRUITING
Conditions: Critical Illness
Interventions: OTHER: Early rehabilitation protocol for children hospitalized in the PICU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: You Are What You Eat: Food as a Risk Factor and a Treatment for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: OTHER: Low UPF Meals (Study Provided)|OTHER: Low UPF Nutritional Guidance|OTHER: Low UPF Snacks (Study Provided)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MYocardial DOmmages Related to COVID-19
Status: COMPLETED
Conditions: Covid19|Non Ischemic Myocardial Injury|Myocardial Infarction|Myocarditis|Troponin Elevation
Interventions: BIOLOGICAL: Biological data|OTHER: Clinical data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Immunonutrition on the Improvement of Postoperative Adjuvant Chemotherapy Related Adverse Reactions in Patients With Gastrointestinal Tumors
Status: RECRUITING
Conditions: Gastrointestinal Tumors|Immunonutrition|Postoperative Adjuvant Chemotherapy
Interventions: DRUG: Immunonutrition （Su yusu)|DRUG: fluorouracil based chemotherapy regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of Pimavanserin in Patients With Parkinson's Disease Psychosis
Status: RECRUITING
Conditions: Parkinson's Disease Psychosis
Interventions: DRUG: pimavanserin tartrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Spray Silicone in Alteration of Burn Scar
Status: WITHDRAWN
Conditions: Burn Scar
Interventions: OTHER: silicone spray|OTHER: saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of NAP (AL-108) in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AL-108|DRUG: AL-108|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BIOLOGICAL: pUMVC3-IGFBP2-HER2-IGF1R Plasmid DNA Vaccine|DRUG: Paclitaxel|BIOLOGICAL: Trastuzumab|BIOLOGICAL: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APE-Study: Ablation of Barrett's Mucosa vs. Surveillance Without Ablation in Patients Cured From Barrett's Cancer Combined With Randomization of Esomeprazole vs. Placebo for Symptomatic Reflux Control After Successful Barrett's Ablation
Status: TERMINATED
Conditions: Barrett's Esophagus
Interventions: DRUG: esomeprazole treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic Disease
Status: COMPLETED
Conditions: Cardiovascular Disease|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: wholegrain cereals oats (WGO)|DIETARY_SUPPLEMENT: Non wholegrain cereals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sensor Augmented Pump (SAP) Therapy for Inpatient CFRD Management
Status: TERMINATED
Conditions: Cystic Fibrosis-related Diabetes|Cystic Fibrosis Pulmonary Exacerbation|Cystic Fibrosis in Children
Interventions: DEVICE: Sensor Augmented Pump Therapy|DEVICE: Standard of Care with CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real World Study of the Efficacy and Safety of Flumatinib Versus Imatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase
Status: NOT_YET_RECRUITING
Conditions: CML, Chronic Phase
Interventions: DRUG: Flumatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternate Nostril Breathing on Cardiorespiratory Functions in Phase 1 Post CABG Patients
Status: COMPLETED
Conditions: Post-cardiac Surgery
Interventions: OTHER: Standardized Physical therapy protocol|OTHER: Alternate nostrils breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Covered Self-expandable Dual-layered Metallic Mesh Stent (UVENTA) in Ureteral Obstruction
Status: UNKNOWN
Conditions: Ureteral Obstruction
Interventions: DEVICE: cSEMS(Covered self-expandable dual-layered metal stent) implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Gallium Ga 68-HA-DOTA-TATE|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioavailability Study of Vemurafenib in Participants With BRAF^V600 Mutation-Positive Malignancies
Status: COMPLETED
Conditions: Malignant Melanoma, Cancer
Interventions: DRUG: Vemurafenib|DRUG: 14C-Labeled Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate Safety, Pharmacokinetics, and Antiviral Activity of Bictegravir (GS-9883) in Human Immunodeficiency Virus (HIV)-1 Infected Participants
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Bictegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assistive Soft Robotic Glove (EsoGLOVE) Intervention for Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: EsoGLOVE with Trigno Biofeedback (EMG sensors)|OTHER: Graded Repetitive Arm Supplementary Program (GRASP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Intervention
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Breast Cancer Treatment Related Lymphedema
Interventions: DEVICE: Juzo Compression Sleeve and Glove|DEVICE: Compression Sleeve Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryopreserved vs. Lyopreserved Stravix as an Adjunct to NPWT in the Treatment of Complex Wounds
Status: COMPLETED
Conditions: Diabetic Wound
Interventions: DEVICE: NPWT and lyopreserved Stravix|DEVICE: NPWT and cryopreserved Stravix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole to Reduce Organ Failure in Sepsis
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Treatment With Epoetin Alfa on Hemoglobin Levels, Red Blood Cell Transfusions, and Quality of Life in Patients With Cancer Receiving Platinum-containing Chemotherapy
Status: COMPLETED
Conditions: Anemia|Neoplasm
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-Part Study for Dose Determination of Vesleteplirsen (SRP-5051) (Part A), Then Dose Efficacy (Part B) in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Vesleteplirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Progressive Muscle Relaxation on Psychological Symptoms and Mental Well-Being in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenic Psychoses
Interventions: BEHAVIORAL: Progressive Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of BOS161721 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BOS161721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study To Describe The Safety Of 13-valent Pneumococcal Conjugate Vaccine In Children 6 To 17 Years Of Age In India
Status: COMPLETED
Conditions: Vaccines
Interventions: BIOLOGICAL: 13vPnC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction
Status: TERMINATED
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Functional Deformities|Pseudoarthrosis|Revision of Endoprosthesis-treated Hips|Fracture, Proximal Humeral|Provision of Non-endoprosthetic Previous Operations of the Hip Joint (e.g., Transposition Osteotomies)|Femur Fracture|Pseudarthrosis|Trochanteric Fractures|Bridging of Large Bone Defects|Revisions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-in-man Evaluation of a Novel, Microcrystalline Paclitaxel Coated Balloon for Treatment of Femoropopliteal Artery Disease (PAX-r)
Status: COMPLETED
Conditions: Peripheral Artery Disease|Femoropopliteal Artery Disease
Interventions: DRUG: Local drug delivery via microcrystalline paclitaxel balloon coating (PAK,Balton, Poland)|DEVICE: Plain balloon angioplasty, uncoated balloon (Neptun, Balton, Poland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With HBV Related Liver Fibrosis
Status: UNKNOWN
Conditions: Hepatitis B|Liver Fibrosis
Interventions: DRUG: Tenofovir Disoproxil Fumarate|DRUG: Peginterferon Alfa-2a|DRUG: Peginterferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Particle Steroids in Refractory Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacologically Triggered Migraine Without Aura and Neuroimaging
Status: UNKNOWN
Conditions: Migraine With Aura
Interventions: DRUG: Calcitonin Gene-Related Peptide|DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of OSTAP and EOIP Blocks in Laparoscopic Cholecystectomies
Status: RECRUITING
Conditions: Analgesia|Pain, Post Operative
Interventions: OTHER: EOIP|OTHER: OSTAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PEG-Interferon a-2b + Ribavirin for Treatment of Patients With Chronic Hepatitis C Who Have Previously Failed to Achieve a Sustained Virologic Response Following Interferon Alfa or Interferon a-2b + Ribavirin Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: PEGIntron plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Digital Intervention for Alleviating Diabetes-specific Emotional Distress in Adults Living With T2DM
Status: NOT_YET_RECRUITING
Conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus)|Metabolic Disease|Endocrine System Diseases|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: covivio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Trial for Acute Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Acute Central Serous Chorioretinopathy
Interventions: DEVICE: 577-MPL|DEVICE: 577-TL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Enabled Readiness for First 1000 Days Learning Ecosystem
Status: UNKNOWN
Conditions: Emotional Well-being of First-time Families|Nutritional Health of Mother and Child|Parenting Self-Efficacy for First-time Families|Experience of First-time Families
Interventions: BEHAVIORAL: Arm 2:Behavioral Intervention with nudges & Facebook interaction|OTHER: Arm 3: Community Intervention with individualised teleconferencing sessions and phone calls.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Intrathecal MSC-NP injection|OTHER: Intrathecal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Misotac vs Combined Oral Contraceptive Pill in the Treatment of Symptomatic Isthmocele
Status: UNKNOWN
Conditions: Dysfunctional Uterine Bleeding
Interventions: DRUG: medical treatment of isthmocele
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Technical Optimization of Detection of KRAS, BRAF and NRAS Mutations on Tumor DNA Circulating in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: KRAS, NRAS et BRAF mutation analysis from circulating plasma DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Full Digital Fabricated Ocular Prosthesis Versus Conventional Fabricated Technique
Status: NOT_YET_RECRUITING
Conditions: Occluar Prosthesis
Interventions: OTHER: Digital occluar prosthesis|OTHER: Conventional occluar prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self Acupressure Application on Pain, Fatigue and Sleep Quality in Multiple Myeloma Patients
Status: RECRUITING
Conditions: Self Acupressure|Sleep|Fatigue
Interventions: OTHER: Self acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Head and Neck Cancer|Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT