pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tissue Characterization With Hyperspectral Imaging (HSI)
Status: UNKNOWN
Conditions: Tissue Perfusion|Tumor|Inflammation|Inflammatory Bowel Diseases
Interventions: PROCEDURE: Hyperspectral imaging|DIAGNOSTIC_TEST: Lactate acid measurement|DIAGNOSTIC_TEST: pathological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Developing a Mobile Intervention to Reduce Suicidal Cognitions in Veterans
Status: COMPLETED
Conditions: Suicide
Interventions: BEHAVIORAL: Mobile Intervention for Suicidal Thoughts (MIST)|BEHAVIORAL: Mobile Intervention for Reducing Anger (MIRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfer of Technological Innovations to Nursing Practice: A Contribution to the Prevention of Infections
Status: COMPLETED
Conditions: Catheterization, Peripheral
Interventions: DEVICE: Ultrasound|DEVICE: Near Infrared Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Cytoflavin (Inosine + Nicotinamide + Riboflavin + Succinic Acid)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Immunity Following IPV Versus fIPV: a Community Based Randomized Controlled Trial in Pakistan
Status: UNKNOWN
Conditions: Poliovirus Vaccine, Inactivated|Poliomyelitis|Immunization; Infection
Interventions: BIOLOGICAL: Inactivated Poliovirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC
Status: RECRUITING
Conditions: Lung Cancer Non-small Cell Stage IV|Brain Metastases
Interventions: DRUG: Osimertinib|RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Condition in Giant Obese Patients
Status: COMPLETED
Conditions: Morbid Obesity|Bariatric Surgery Candidate
Interventions: DRUG: Liraglutide|OTHER: Aminosteril hepa 8%|DIETARY_SUPPLEMENT: Caloric diet with 1000 kcal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Senofilcon A Investigational Manufacturing Process
Status: COMPLETED
Conditions: Visual Acuity|Comfort|Overall Vision
Interventions: DEVICE: senofilcon A|DEVICE: senofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transauricular Vagus Nerve Stimulation in the Treatment of Chemotherapy-induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: CIPN|Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Vagus nerve stimulation|DEVICE: sham vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction (SVF) Therapy in Patients With Acute Spontaneous Intracerebral Hemorrhage (SICH).
Status: RECRUITING
Conditions: Spontaneous Intracerebral Hemorrhage
Interventions: BIOLOGICAL: SVF therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Oral treprostinil (UT-15C) Sustained Release Tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Surgical Pleth Index in Guiding Anesthesia in Gastroenterological Surgery
Status: COMPLETED
Conditions: Intraoperative Complications|Intraoperative Hypotension|Intraoperative Hypertension
Interventions: DEVICE: SPI|DEVICE: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesiotaping and Night Splinting in Patients With Carpal Tunnel Syndome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Kinesiotaping|OTHER: Night Splinting|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
Status: WITHDRAWN
Conditions: COVID-19 Patients
Interventions: DRUG: HCQ & AZ vs HCQ+SIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NS-9 in Patients With Liver Metastases
Status: COMPLETED
Conditions: Liver Neoplasms|Neoplasm Metastasis|Local Neoplasm Recurrences
Interventions: DRUG: NS-9 [Poly I: Poly C]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Caffeic Acid Phenethyl Ester as a Matrix Metalloproteinase Inhibitor: Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Matrix Metalloproteinase Inhibitors|Composite Resins
Interventions: DRUG: total-etch adhesive|DRUG: CAPE-T|DRUG: self-etch adhesive|DRUG: CAPE-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neurotoxicity|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: baclofen/amitriptyline/ketamine gel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Support for the Resumption of Training of High-level Athletes Post-epidemic COVID-19
Status: COMPLETED
Conditions: COVID-19|Myocarditis
Interventions: DIAGNOSTIC_TEST: Resting electrocardiogram|DIAGNOSTIC_TEST: Stress test|DIAGNOSTIC_TEST: Cardiac echocardiography|DIAGNOSTIC_TEST: Cardiac rhythm monitoring|OTHER: Questionnaire|DEVICE: Injected Cardiac MRI|BIOLOGICAL: Blood sampling for biobank
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women
Status: RECRUITING
Conditions: Obese|Weight Loss|Body Weight|Cardiometabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column
Status: RECRUITING
Conditions: Spine Metastases|Metastasis Spine
Interventions: RADIATION: Spine stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Acute Coronary Syndrome Patient Delay
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Text+Visual BCT-based intervention|BEHAVIORAL: Text-only BCT intervention|BEHAVIORAL: Leaflet information (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MINDFUL-PC: Integrating Mindfulness Into the Patient-Centered Medical Home
Status: COMPLETED
Conditions: Depression|Anxiety|Stress Related Disorder|Adjustment Disorder
Interventions: BEHAVIORAL: Mindfulness Training for Primary Care|BEHAVIORAL: Mindfulness Intro. +resources +waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Massage
Status: COMPLETED
Conditions: Healthy|Pain
Interventions: OTHER: Pain Inducing Massage|OTHER: Pain Free Massage|OTHER: Positive Expectation Instructional Set|OTHER: Negative Expectation Instructional Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Probiatop In The Treatment Of Digestive Symptoms
Status: COMPLETED
Conditions: Signs and Symptoms, Digestive
Interventions: DRUG: Probiatop|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laval University Rouge et or Post ACL Surgery Program Effectiveness
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries|ACL
Interventions: OTHER: Rouge et Or Program|OTHER: CHU intervention guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph- B-ALL
Status: RECRUITING
Conditions: B-Cell Acute Lymphoblastic Leukemia, Adult
Interventions: DRUG: CAR-T cells targeting CD19 and CD22
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS
Status: COMPLETED
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Irinotecan, Toripalimab in RAS/BRAF Wild-type Ultraselected Right-sided Colorectal Cancer Study
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Cetuximab|DRUG: Toripalimab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain
Status: COMPLETED
Conditions: Inflammation|Pruritus|Hyperalgesia
Interventions: OTHER: Topical L-menthol 40%|OTHER: Vehicle, topical ethanol 96%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Assessment of Platelet Reactivity After the Intake of Oleocanthal
Status: COMPLETED
Conditions: Platelet Aggregation|Nutritional and Metabolic Disease|Cardiovascular Diseases
Interventions: OTHER: Oleocanthal-Rich Extra Virgin Olive Oil|OTHER: Oleocanthal-low Extra Virgin Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Participants Ages 21-65 Diagnosed With Dyspareunia and the Effects of Low Intensity Shockwave Treatment
Status: RECRUITING
Conditions: Female Dyspareunia
Interventions: DEVICE: Low intensity shockwave treatment to pelvic floor region plus typical physical therapy|DEVICE: Sham shockwave treatment plus typical physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Automated Office Blood Pressure Monitoring
Status: COMPLETED
Conditions: Hypertension|Uncontrolled Hypertension|Hypertension, White Coat|Hypertension, Resistant to Conventional Therapy
Interventions: DEVICE: Blood pressure measurement device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Jet or Vibrating Mesh Nebulisation for Secretion Management in ICU
Status: RECRUITING
Conditions: Respiratory Failure|Critical Illness
Interventions: PROCEDURE: Continuous nebulisation 0.9% saline Aerogen Solo vibrating mesh Nebuliser|PROCEDURE: Intermittent nebulisation 0.9% saline Aerogen vibrating mesh Solo Nebuliser|PROCEDURE: Intermittent standard intermittent nebulisation of 0.9% saline Intersurgical Cirrus 2 self sealing Jet Nebuliser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pentoxifylline on Proteinuria in Korean Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Etafilcon A Contact Lenses Using a Novel Molding Process
Status: TERMINATED
Conditions: Refractive Error Correction
Interventions: DEVICE: Test/Control|DEVICE: Control/Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Versus Intramuscular Polio Vaccine Booster in HIV-Infected Subjects
Status: COMPLETED
Conditions: Polio Immunity
Interventions: DRUG: IPOL (Sanofi Pasteur) inactivated polio vaccine booster dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Homoeopathy and Yoga in the Treatment of Menstrual Disorders in Females With Polycystic Ovarian Syndrome
Status: UNKNOWN
Conditions: Menstrual Disorders|Polycystic Ovary Syndrome
Interventions: OTHER: Homoeopathic Remedies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Use of Salt Poor Albumin Solution in Resuscitation of Orthotopic Liver Transplant
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: DRUG: Albumin infusion (25% albumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NT 201 (Xeomin®/Bocouture®) in Comparison With Clostridium Botulinum Toxin Type A in the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: NT 201 (IncobotulinumtoxinA (Xeomin®/Bocouture®))|DRUG: OnabotulinumtoxinA (Vistabel®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects
Status: RECRUITING
Conditions: Chronic Pain
Interventions: OTHER: Spinal Cord Stimulator Set to Minimal/No Stimulation Setting|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome
Status: COMPLETED
Conditions: Epilepsy|Dravet Syndrome
Interventions: DRUG: GWP42003-P|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Alcohol Dependence|Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Oxidant Treatment of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Vitamin E, Vitamin C, and Alpha-lipoic Acid|DRUG: Coenzyme Q|DRUG: Placebo capsules|DRUG: Placebo wafers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunochemotherapy in Locally Advanced Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Esophagogastric Junction Adenocarcinoma
Interventions: DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TA-CIN Vaccine With Anti-PD-1 Therapy in Recurrent HPV16-associated Cancers
Status: WITHDRAWN
Conditions: Recurrent Human Papillomavirus Type 16 Associated Cancer
Interventions: DRUG: HPV 16 TA-CIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial on the Opportunity and Treatment of Residual Deformity After Reduction in Developmental Dislocation of the Hip
Status: NOT_YET_RECRUITING
Conditions: Developmental Dislocation of the Hip|Congenital Dislocation of Hip|Residual Deformity|Reduction
Interventions: PROCEDURE: Pelvic osteotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of TOTUM-854 on Blood Pressure in Subjects With Moderately Elevated Blood Pressure
Status: ACTIVE_NOT_RECRUITING
Conditions: Prehypertension|Elevated Blood Pressure|Blood Pressure|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: TOTUM-854|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism
Status: ACTIVE_NOT_RECRUITING
Conditions: Deep Vein Thrombosis|Pulmonary Embolism|Venous Thromboembolism
Interventions: DRUG: Apixaban 2.5 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Qiliqiangxin Capsule to Treat Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy|Heart Failure
Interventions: DRUG: Qiliqiangxin capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block and Sugammadex Versus Standard of Care on Quality of Recovery in Patient Undergo Elective Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Neuromuscular Block
Interventions: DRUG: Deep neuromuscular block|DRUG: Moderate neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Brexpiprazole in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Distribution of Lateral Femoral Cutaneous Nerve Block
Status: COMPLETED
Conditions: Nerve Block|Anesthesia, Local|Pain, Postoperative|Anatomical Distribution
Interventions: DRUG: Ropivacaine|DRUG: Isotonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prochymal® (Human Adult Stem Cells) Intravenous Infusion Following Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Prochymal®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Strategy of Preventing Post-operative Opioid-induced Hyperalgesia
Status: UNKNOWN
Conditions: Opioid-Induced Disorders
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of m CIMT and Bilateral Arm Training on Upper Extremity Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: Bilateral Arm Training|COMBINATION_PRODUCT: modified constrained induce movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Self-reported Symptoms as a Proxy for Acute Organophosphate Poisoning Among Nepali Farmers
Status: COMPLETED
Conditions: Organophosphate Poisoning
Interventions: OTHER: Organophosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/Methylcellulose
Status: RECRUITING
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PUFAs and Left Ventricular Function in Heart Failure
Status: COMPLETED
Conditions: Dilated Cardiomyopathy|Heart Failure
Interventions: DRUG: n-3 PUFAs|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Research of Novel Electrolyzed Water Spray to Eradicate Bacteria E-coli and an Attenuated Human Flu Virus
Status: COMPLETED
Conditions: Bacterial Growth|Novel Influenza A (H1N1)
Interventions: DEVICE: A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Paclitaxel Plus Carboplatin Versus Anthracyclines Followed by Docetaxel as Adjuvant Chemotherapy for Triple Negative Breast Cancer (PATTERN)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: 5-fluorouracil|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations
Status: TERMINATED
Conditions: Snake Envenomation
Interventions: BIOLOGICAL: Crotaline Polyvalent Immune Fab (ovine) (active initial and maintenance therapy)|BIOLOGICAL: Crotaline Immune Fab (ovine) (active initial therapy; placebo maintenance therapy)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-prandial Hypotension and Sleepiness in Parkinson's Disease and Other Synucleinopathies
Status: COMPLETED
Conditions: Parkinsonian Disorders
Interventions: OTHER: V1: HGPO + meal and V2: placebo + meal|OTHER: V1: placebo 75mg + meal and V2: HGPO 75mg + meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in Cardiac Deformation Following Physiologic Alterations and Inotropic Support.
Status: COMPLETED
Conditions: Heart Failure, Diastolic|Aortic Valve Stenosis|Monitoring, Physiologic|Physiology
Interventions: DRUG: Levosimendan|DRUG: Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clofarabine Pre-conditioning With Allogeneic Transplant for Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia|Myelodysplasia
Interventions: DRUG: Clofarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trisenox, Ascorbic Acid and Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Arsenic Trioxide, Ascorbic Acid and Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Calcitonin in the Treatment of Bone Mineral Loss in Children and Adolescents With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Calcitonin nasal spray (salmon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Study of Zifibancimig in Participants With Neovascular Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Macular Degeneration
Interventions: DRUG: Zifibancimig|DRUG: Ranibizumab|DEVICE: Port Delivery Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPIC European Study: Use of the FiberNet® Emboli Protection Device in Carotid Artery Stenting
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: FiberNet Embolic Protection Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Macitentan 10mg|DRUG: Placebo sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Through Knee Amputation Versus Above Knee Amputation Regarding Infection Rate and Function
Status: NOT_YET_RECRUITING
Conditions: Amputation of Knee
Interventions: PROCEDURE: Through knee amputation|PROCEDURE: Above knee Amputation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blue Light Photodynamic Therapy Treatment for Distal and Lateral Subungual Toenail Onychomycosis
Status: COMPLETED
Conditions: Toenail Onychomycosis|Distal and Lateral Subungual Toenail Onychomycosis
Interventions: PROCEDURE: Aminolevulinic Acid (ALA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Retinal Degeneration
Interventions: DEVICE: Device name: "Retina Implant model Alpha". Surgical implantation of medical device into eye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EFficacy and SaFEty of Leukotac (Inolimomab) in Pediatric Patients With SR-aGvHD
Status: UNKNOWN
Conditions: Steroid Refractory GVHD
Interventions: BIOLOGICAL: Inolimomab (Leukotac)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Blood Glucose Fluctuation With Usage of Polyherbal
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Polyherbal capsule coccinia, bougainvillea, catharanthus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Amlodipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study of Qsymia in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Qsymia 3.75Mg-23Mg Extended Release Capsule|DRUG: Qsymia 7.5Mg-46Mg Extended Release Capsule|DRUG: Qsymia 11.25Mg-69Mg Extended Release Capsule|DRUG: Qsymia 15Mg-92Mg Extended Release Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: R-(-)-gossypol acetic acid|DRUG: temozolomide|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder
Status: COMPLETED
Conditions: HIV Infections|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Depression|Substance Abuse
Interventions: DRUG: Twinrix|BEHAVIORAL: Enhanced treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MEK162 (Binimetinib) in Combination With Pexidartinib in Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: MEK162|DRUG: Pexidartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-national, Randomized, Phase III, GCIG Intergroup Study Comparing Pegylated Liposomal Doxorubicin (CAELYX) and Carboplatin vs. Paclitaxel and Carboplatin in Patients With Epithelial Ovarian Cancer in Late Relapse. (CALYPSO)
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: pegylated liposomal Doxorubicin (CAELYX) & Carboplatin|DRUG: Paclitaxel & Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Imagery and Transcranial Direct Current Stimulation (tDCS) in Women With Chronic Pelvic Pain
Status: TERMINATED
Conditions: Cystitis, Interstitial|Pelvic Pain
Interventions: OTHER: Guided imagery plus active tDCS|OTHER: Guided imagery plus Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Stewardship for Primary Care Pediatricians
Status: COMPLETED
Conditions: Acute Sinusitis|Streptococcal Pharyngitis|Pneumonia|Viral Infection
Interventions: BEHAVIORAL: Antimicrobial Stewardship Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess if Immune Response of GSK Biologicals' Tritanrix™-HepB/Hib-MenAC Given Without or With Hepatitis B Vaccine at Birth is at Least as Good as Tritanrix™-HepB/Hiberix™ Without Hepatitis B Vaccine at Birth, When Given to Healthy Infants
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Diphtheria|Whole Cell Pertussis|Hepatitis B|Tetanus
Interventions: BIOLOGICAL: DTPw-HBV/Hib-MenAC conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Response of Alkylresorcinols to Different Cereals
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Refined wheat flour|OTHER: Esterase wholegrain wheat flour|OTHER: Wholegrain wheat flour|OTHER: Liquid whole grain wheat flour|OTHER: Wholegrain barley flour|OTHER: Liquid wholegrain barley flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Colchicine in Vascular Inflammation Assessed With PET Imaging
Status: COMPLETED
Conditions: Atherosclerotic Vascular Disease
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mesalamine 4 gm/60 mL Rectal Enema
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rowasa® 4 gm/60 mL Rectal Enema|DRUG: Mesalamine 4 gm/60 mL Rectal Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adjuvant IMRT With Concommitant Raltitrexed Chemotherapy for Locally Advanced Gastric Cancer After D0/D1 Radical Resection
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Raltitrexed|RADIATION: postoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Perennial Allergy to House Dust Mite and/or Cat
Interventions: DRUG: CYT003-QbG10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE as an Adjuvant Therapy After Radiofrequency Ablation (RFA) for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: PROCEDURE: radiofrequency ablation|PROCEDURE: TACE after RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synbiotic Approach to Immunity and Metabolism in the Elderly Study
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: LGG+Promitor™|DIETARY_SUPPLEMENT: Promitor™|DIETARY_SUPPLEMENT: LGG-PB12+Promitor™|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nitric Oxide in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO)
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation|Nitric Oxide|Shock, Cardiogenic
Interventions: DRUG: Inhaled nitric oxide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed Non Hodgkin Lymphoma
Interventions: DRUG: CAR19 T cells carrying cytoplasmic activated PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Sitagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Whether Naproxen and Darexaban (YM150) Interact in Their Effects
Status: COMPLETED
Conditions: Pharmacodynamic Interaction|Healthy Subjects
Interventions: DRUG: darexaban|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients With Chronic Hepatitis C Virus (MAGELLAN-2)
Status: COMPLETED
Conditions: Chronic Hepatitis C|HCV|Hepatitis C Virus
Interventions: DRUG: glecaprevir/pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of QS-M Needle- Free Injector and Insulin Pen in Controlling T2DM Patient's Glucose
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: QS-M insulin-free injector|DEVICE: conventional insulin pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography (PET) Study to Describe the Relationship Between Plasma Concentrations and Brain Gly-T1 Occupancy of GSK1018921 Over Time.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: GSK1018921
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coping After Breast Cancer - a Randomized Clinical Trial With Two Digital Interventions
Status: RECRUITING
Conditions: Breast Cancer Patients|Health, Subjective
Interventions: OTHER: Stressproffen cognitive based stress management|OTHER: Stressproffen mindfulness based intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: [68 Ga]-DOTANOC PET/CT in GEP-NETs
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: [68Ga]-DOTANOC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: BIOLOGICAL: Bone Marrow Aspirate Concentrate|DEVICE: Angel Concentrated Platelet Rich Plasma (cPRP) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy and Safety of Mycamine® and Itraconazole for Preventing Fungal Infections
Status: COMPLETED
Conditions: Fungemia|Fungal Infections
Interventions: DRUG: micafungin (Mycamine)|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Sildenafil Following Administration of an Chewable Tablet of Sildenafil Relative to Viagra® Conventional Oral Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: HIP0908|DRUG: viagra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotyping of Adult Crohn's Focusing on Sarcopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Sarcopenia|Digestive System Disease|Nutrition, Healthy|Protein Malabsorption|Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Intrinsically labelled protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alleviant ALLAY-HF Study
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure
Interventions: DEVICE: Alleviant ALV1 System|OTHER: Sham-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Different Kinesio Taping Applications on Pain and Functional Mobility in Pregnants With Lumbopelvic Pain
Status: COMPLETED
Conditions: Lumbopelvic Pain
Interventions: OTHER: Lumbopelvic kinesio taping|OTHER: Abdominal supported lumbopelvic kinesio taping|OTHER: Placebo tapng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin With Ferrous Gluconate Versus Ferrous Gluconate in Treatment of Iron Deficiency Anemia During Pregnancy
Status: COMPLETED
Conditions: Lactoferrin With Ferrous Gluconate More Superior Than Ferrous Gluconate Alone in Treatment of Iron Deficiency Anemia
Interventions: DRUG: Ferrous Gluconate 300 MG|DRUG: ferrous gluconate with lactoferrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grazax Asthma Prevention
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Grazax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxaliplatin in Treating Patients With Metastatic Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Venetoclax|DRUG: Polatuzumab Vedotin|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Dexamethasone Followed by ASCT Compared With ASCT Alone in Treating Patients With AL Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: Bortezomib|DRUG: dexamethasone|BIOLOGICAL: filgrastim|PROCEDURE: autologous hematopoietic stem cell transplantation (ASCT)|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Incidence of Cholangiocarcinoma on Choledochal Cyst in a Western Center
Status: RECRUITING
Conditions: Incidence of Cholangiocarcinoma on Choledochal Cysts|Postoperative Complications in Choledochal Cysts|Choledochal Cyst Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gut Microbiome in Biliary Atresia
Status: UNKNOWN
Conditions: Biliary Atresia
Interventions: OTHER: Monitoring of the gut-microbiome and ultrasound elasticity.|OTHER: Monitoring of the gut-microbiome|OTHER: Monitoring of the gut-microbiome|OTHER: Monitoring of the gut-microbiome.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock
Status: RECRUITING
Conditions: Norepinephrine|Hemorrhagic Shock|Hypotensive Resuscitation
Interventions: DRUG: Low dose of Norepinephrine (NE)|DRUG: High dose of Norepinephrine (NE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Placebo|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Trial With Single-dose C5a-neutralizing AON-D21 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Intravenous AON-D21|DRUG: Intravenous placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effectiveness of Bupivacaine With and Without Dexmedetomidine in Patients With Abdominal Surgery
Status: COMPLETED
Conditions: Post Operative Pain|Bradycardia|Hypotension|Nausea|Vomiting
Interventions: DRUG: bupivacaine wound infilteration|DRUG: Bupivacaine plus dexmedetomidine wound infilteration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT