pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Homeopathic Remedy for the Third Stage of Delivery
Status: COMPLETED
Conditions: Third Stage of Labor
Interventions: DRUG: Homeopathy 1|DRUG: Homeopathy 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy
Status: RECRUITING
Conditions: Breast Carcinoma|Esophageal Carcinoma|Genitourinary System Carcinoma|Head and Neck Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|Lung Carcinoma|Malignant Central Nervous System Neoplasm|Malignant Digestive System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Aerobic Exercise Training in Patients With Type III Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Neuromuscular Diseases|Spinal Muscular Atrophy Type 3
Interventions: OTHER: Aerobic Exercise Training|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Eluting Balloon and Conventional Balloon for In-Stent Restenosis of the Superficial Femoral Artery
Status: UNKNOWN
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: PTA|DEVICE: PTA with PEB|PROCEDURE: Percutaneous Transluminal Angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of RV-Dysfunction in Fallot Patients
Status: COMPLETED
Conditions: Tetralogy of Fallot
Interventions: OTHER: Transthoracic echocardiography at rest, during PLR, HG and CPX (including blood gas analysis in both groups). Additionally Fallot patients will undergo routine blood testings.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy
Status: NOT_YET_RECRUITING
Conditions: Asthma|Allergy
Interventions: DRUG: HDM sublingual Immunotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Mydrane ® for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma.
Status: COMPLETED
Conditions: Cataract Surgery
Interventions: DRUG: Efficacy of a Standardized Intracameral Combination of Mydriatics and Anesthetic (Mydrane ®) for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRay to Treat Polypoidal Choroidal Vasculopathy (PCV) Secondary to Age-Related Macular Degeneration (AMD
Status: UNKNOWN
Conditions: Polypoidal Chorodial Vasculopathy|Age Related Macular Degeneration
Interventions: RADIATION: Iray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 QT Study in Healthy Male Subjects
Status: COMPLETED
Conditions: Clinical Pharmacology, Healthy Volunteer Study
Interventions: DRUG: Placebo|DRUG: Pomalidomide|DRUG: Pomalidomide|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison Study of Conventional POEM and Hybrid POEM for Esophageal Achalasia
Status: UNKNOWN
Conditions: Esophageal Achalasia
Interventions: PROCEDURE: Water-jet POEM|PROCEDURE: Conventional POEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Autologous Bone Marrow Aspirate Concentrate Injections for Musculoskeletal Conditions
Status: WITHDRAWN
Conditions: Musculoskeletal Pain|Osteoarthritis|Tendinopathy|Sprains Strain
Interventions: PROCEDURE: Bone Marrow Aspirate Concentrate Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia|Astigmatism
Interventions: DEVICE: Topography Guided LASIK Surgery|DEVICE: Small Incision Lenticule Extraction Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Retrovirally Mediated Transfer of the Human Glucocerebrosidase Gene Into Peripheral Blood Stem Cells for Autologous Transplantation in Patients With Type I Gaucher Disease
Status: COMPLETED
Conditions: Gaucher's Disease
Interventions: GENETIC: human glucocerebrosidase gene into autologous peripheral blood stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Duvelisib With Rituximab vs R-CHOP in Subjects With Relapsed/Refractory Follicular Lymphoma (FRESCO)
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Rituximab|DRUG: R-CHOP|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy
Status: UNKNOWN
Conditions: Primary IgA Nephropathy
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardizing the Management of Patients With Coronary Microvascular Dysfunction
Status: RECRUITING
Conditions: Coronary Artery Disease|Microvascular Angina|Microvascular Ischemia of Myocardium
Interventions: OTHER: MULTI-DOMAIN LIFESTILE INTERVENTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Implementation Coaching to Support Successful EBP Delivery
Status: RECRUITING
Conditions: Standard/As Usual CBT+/EBP Initiative Implementation|Optimized Supervisor-led Implementation Coaching
Interventions: BEHAVIORAL: Supervisor-led Implementation Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Influence of Different Food Componente on Zinc Absorption in Young Adults Consuming Zinc Fortified Porridges Prepared From Maize, Beans and Sorghum: a Series of Six Similar Randomized, Single-blind Studies
Status: COMPLETED
Conditions: Study Not Related to a Disease. Nutrition Study Without Drug Administration.
Interventions: PROCEDURE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People
Status: COMPLETED
Conditions: Renal Impairment|Healthy Volunteers
Interventions: DRUG: Bocidelpar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMC435-TiDP16-C117: The Effect of TMC435 on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy Volunteers
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435|DRUG: Placebo for TMC435|DRUG: TMC435|DRUG: Placebo for TMC435|DRUG: Moxifloxacin|DRUG: Placebo for moxifloxacin|DRUG: Placebo for TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vevorisertib (ARQ 751) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations (MK-4440-001)
Status: TERMINATED
Conditions: Cancer|Solid Tumors
Interventions: DRUG: Vevorisertib|DRUG: Fulvestrant|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Onset of Action of a Fast Release Aspirin
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Acetylsalicyclic acid (Fast release Aspirin, BAY1019036)|DRUG: Acetaminophen (Tylenol extra strength)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of MP-513 in Combination With Thiazolidinedione in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo / Teneli (Teneligliptin) + pio (pioglitazone)|DRUG: Teneli / Teneli + pio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: LDE225-600mg|DRUG: Gemcitabine|DRUG: nab-paclitaxel|DRUG: LDE225-400mg|DRUG: LDE225-800mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Osteopathic Assessment of Lower Extremity Somatic Dysfunction in Runners
Status: COMPLETED
Conditions: Somatic Dysfunction of Sacral Region|Somatic Dysfunction of Both Sacroiliac Joints|Somatic Dysfunction of Bilateral Lower Extremities
Interventions: OTHER: Osteopathic Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Genexol-PM and Cisplatin in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: genexolPM + cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor Cancer
Interventions: DRUG: ABBV-CLS-484|DRUG: Programmed Cell Death-1 (PD-1) Inhibitor|DRUG: Vascular Endothelial Growth Factor Receptor (VEGFR) Tyrosine Kinase Inhibitor (TKI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Coadministration of Itraconazole on the Pharmacokinetics of CRD-740
Status: COMPLETED
Conditions: Clinical Pharmacology|Pharmacokinetics|Cardiovascular Diseases|Heart Failure
Interventions: DRUG: CRD-740|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Procedure of Early Liver Transplantation in Alcoholic Hepatitis Resisting to Medical Treatment
Status: COMPLETED
Conditions: Alcoholic Hepatitis|Alcoholic Cirrhosis
Interventions: PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Validity of [18F]FSPG PET for the Assessment of Acute Rejection After Heart or Liver Transplantation
Status: COMPLETED
Conditions: Graft Rejection|Heart Transplantation|Liver Transplantation
Interventions: DRUG: [18F]FSPG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thunderbeat Technology vs Standard Bipolar Electro-surgery in Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Thunderbeat technology|PROCEDURE: Standard bipolar electrosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Regorafenib With PF-03446962 to Treat Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: PF-03446962|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy in Patients With Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis|Inflammatory Disease|Arthritis
Interventions: BEHAVIORAL: 12-week home based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient-Centered Chronic Pain Care
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Opioid Use|Musculoskeletal Pain
Interventions: BEHAVIORAL: Pain Manager + tailored implementation support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diagnostic Yield of Agitated Exudative Non-infected Pleural Effusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleural Effusion
Interventions: PROCEDURE: Agitated Pleural Fluid Thoracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Radiotherapy|PD-1 Inhibitor|Capecitabine|Nasopharyngeal Carcinoma
Interventions: RADIATION: SBRT radiotherapy + Conventionally fractionated radiotherapy|DRUG: PD-1 inhibitor|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke, Acute|Intracranial Atherosclerosis
Interventions: DRUG: Butylphthalide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)
Status: TERMINATED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: EMA401|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth
Status: COMPLETED
Conditions: Hypoxic Ischaemic Encephalopathy
Interventions: DRUG: Xenon gas|OTHER: Whole body cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Composition Monitoring for Determination of the Fluid Status in Volunteers Undergoing Intravenous Fluid Therapy
Status: COMPLETED
Conditions: Fluid Shifts|Body Fluid Compartments
Interventions: DRUG: Elo-mel® (Fresenius Kabi Austria)|DEVICE: Body Composition Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy
Interventions: OTHER: fMRI|OTHER: Neuropsychological Testing|OTHER: Additional electrode implantation|OTHER: Electrical brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Whole Body Vibration Training on Unstable Surface
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: OTHER: Proprioceptive training on a whole body vibration platform|OTHER: Proprioceptive training with the BOSU® on the floor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insertion Angle and Needle Visualization During Ultrasound Guided Internal Jugular Vein Cannulation
Status: UNKNOWN
Conditions: Internal Jugular Vein Cannulation
Interventions: DEVICE: needle PLT-805AT|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide and sitagliptin|DRUG: exenatide and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Wound Infusion in Lumbar or Thoracic Surgery
Status: COMPLETED
Conditions: Lumbar Spine Surgery|Thoracic Spine Surgery
Interventions: DRUG: Ropivacaine|DRUG: Saline solution 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Conjugate Vaccine in Aging Renal Transplant
Status: TERMINATED
Conditions: Renal Transplantation|Aging
Interventions: DRUG: 23 valent pneumococcal polysaccharide vaccine|BIOLOGICAL: 13 valent conjugated pneumococcal vaccine|OTHER: Peripheral blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preventive Fixation of Lower Limbs in Osteogenesis Imperfecta (Brittle Bone Disease) With the Highlight of the Fassier-Duval
Status: UNKNOWN
Conditions: Brittle Bone Disease
Interventions: DEVICE: Fassier-Duval Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Chronic Graft-Versus-Host Disease Following Bone Marrow Transplant
Status: COMPLETED
Conditions: Graft Versus Host Disease|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: DRUG: Western therapy|DRUG: JET|DRUG: Placebo(for JET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing of Micellar Casein, Blended Micellar Casein and Native Whey
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Testing of micellar casein, blended micellar casein and native whey, versus native whey to determine post-ingestion aminoacidemia, glycemia, and insulinemia in young adult men
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of "I-Anticoagulation"in Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Anticoagulants
Interventions: OTHER: Use of "I-Anticoagulation" to make the decision and manage patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Impact of Short Message Services (SMS) on ARV Adherence in Western Kenya
Status: COMPLETED
Conditions: AIDS|Antiretroviral Therapy|Medication Adherence|HIV Infections
Interventions: BEHAVIORAL: Short Message Services to Support ARV therapy adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas
Status: COMPLETED
Conditions: Colorectal Cancer Screening|Cervical Cancer Screening
Interventions: DIAGNOSTIC_TEST: Self-sampling HPV test|DIAGNOSTIC_TEST: Fecal occult blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Patient-Centered Reproductive Decision Support Tool for Women Veterans
Status: RECRUITING
Conditions: Contraception|Contraception Behavior|Prepregnancy Health|Reproductive Health
Interventions: BEHAVIORAL: MyPath Web-Based Informational and Decision Support Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endostar in Combination With Chemoradiotherapy in Patient With Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Quality of Life
Interventions: COMBINATION_PRODUCT: concurrent chemoradiotherapy (CCRT)|DRUG: Endostar for one cycle|DRUG: Endostar for two cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lapdap and Coartemether for Uncomplicated Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Chlorproguanil-dapsone (Lapdap)|DRUG: Lumefantrine-artemether (Coartemether )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Deprivation Therapy +/- Bevacizumab for PSA Recurrence of Prostate Cancer After Definitive Local Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Androgen Deprivation Therapy|DRUG: bicalutamide|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Use of an Antibacterial Honey Dressing for Palatal Wound Healing After Harvesting a Free Gingival Graft
Status: UNKNOWN
Conditions: Healing Wound
Interventions: DRUG: Medihoney dressing|DEVICE: Medihoney dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of MEDI4736 Monotherapy or in Combinations With Tremelimumab in Metastatic Pancreatic Ductal Carcinoma
Status: COMPLETED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: MEDI4736 monotherapy|DRUG: tremelimumab+MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing
Status: UNKNOWN
Conditions: Simple Renal Cyst
Interventions: PROCEDURE: Laparoscopic deroofing|DRUG: 100 g of amino acids supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a New Probiotic Strain in the Reduction of Group B Streptococcus Colonization in Pregnant Women
Status: COMPLETED
Conditions: Gestational Mother|Streptococcus Agalactiae Infection
Interventions: DIETARY_SUPPLEMENT: Lactobacillus salivarius V4II-90|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biofreeze and the Effect on Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Biofreeze 4 % Topical Gel|OTHER: Biofreeze placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients
Status: COMPLETED
Conditions: Hypertension Secondary to Kidney Transplant
Interventions: DRUG: New Medication: Enalapril, Isradipine, Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: TCR-MAGE-A4 T-Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCC
Status: NOT_YET_RECRUITING
Conditions: Unresectable Esophageal Squamous Cell Carcinoma|Locally Advanced Esophageal Squamous Cell Carcinoma|Metastatic Esophageal Squamous Cell Carcinoma
Interventions: DRUG: AK104|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Study of OCT，Gemstone CT and 320-detector Row Spiral CT for Evaluating Restenosis of Coronary Artery Stent
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: CT image for patient with suspected in-stent restenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects
Status: RECRUITING
Conditions: Transthyretin Amyloidosis|Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy|Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy|Polyneuropathies|Cardiomyopathies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-CD30 CAR-T Therapy in Patients With Refractory/Relapsed Lymphocyte Malignancies
Status: UNKNOWN
Conditions: Adult T-Cell Lymphoma/Leukaemia|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|NK/T-cell Lymphoma|Peripheral T Cell Lymphoma|Hodgkin Lymphoma
Interventions: GENETIC: Anti-CD30 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Nodule
Interventions: DEVICE: CT-Guided Biopsy|DEVICE: Navigation bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Parents as Pain Management in Swedish Neonatal Care
Status: COMPLETED
Conditions: Infant Pain Management|Parent-driven Pain Management
Interventions: BEHAVIORAL: Parent-driven pain management with skin-to-skin contact|BEHAVIORAL: Parent-driven pain management with skin-to-skin contact/breastfeeding/parental singing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aerobic Exercise in Women With Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus|Lupus|Autoimmune Disease|Rheumatic Disease
Interventions: OTHER: Treadmill exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: iTBS-DCS in Fibromyalgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: DRUG: D-Cycloserine|DRUG: Placebo oral tablet|DEVICE: iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: Coherex WaveCrest® Left Atrial Appendage Occlusion System|DEVICE: Watchman® LAA Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Clinical Trial Testing the Effectiveness of Telemental Health for Suicidal Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide|Suicidal Ideation|Suicide Attempt
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Therapy (BCBT)|BEHAVIORAL: Present-Centered Therapy (PCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Treatment|Exercise
Interventions: BEHAVIORAL: Acute aerobic exercise|BEHAVIORAL: Acute aerobic-resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Efficacy and Safety of 2% Ketoconazole Cream in Thai Females With Mild Degree of Post - Adolescence Acne
Status: COMPLETED
Conditions: Post - Adolescence Acne
Interventions: DRUG: 2% ketoconazole cream|DRUG: Hydrophilic Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Versus Docetaxel in Participants Previously Treated for Non-Small Cell Lung Cancer (MK-3475-033/KEYNOTE-033)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Randomized, Open-label Study of Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive and p95HER2-positive Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib|BIOLOGICAL: Trastuzumab|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Z-338 in Subjects With and Without Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Z-338
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advantage of Tramadol in Local Analgesia Post-Sternotomy
Status: COMPLETED
Conditions: Heart Surgery Via Sternotomy|Post-operative Analgesia
Interventions: DRUG: Levobupivacaine|DRUG: levobupivacaine|DRUG: tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Natural Extract 2007RD01 Combined With Saw Palmetto in Benign Prostatic Hyperplasia Patients Compared to Saw Palmetto
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DIETARY_SUPPLEMENT: Combination of 2007RD01 and saw palmetto lipidic extract|DIETARY_SUPPLEMENT: Saw palmetto lipidic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of GH Supplementation on the Blastocyst Euploid Rate in AMA Patients--A Retrospective Cohort Study
Status: COMPLETED
Conditions: Growth Hormone|Advanced Maternal Age|PGT-A
Interventions: DRUG: Growth hormone|DRUG: GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Cancer-Related Fatigue Through Systematic Light Exposure
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Breast Cancer|Fatigue|Mild Cognitive Impairment|Light|Quality of Life|Sleep
Interventions: DEVICE: Bright white light|DEVICE: Dim red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.
Status: COMPLETED
Conditions: Respiratory Depression
Interventions: DRUG: Belbuca 300 µg|DRUG: Belbuca 600 µg|DRUG: Belbuca 900 µg|DRUG: Oxycodone 30 mg|DRUG: Oxycodone 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of KMC on Neurobehavior of Preterm Neonates
Status: COMPLETED
Conditions: Neonatal Neurobehavior
Interventions: BEHAVIORAL: KMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Finding Study of Oral Ibrexafungep (SCY-078) vs. Oral Fluconazole in Subjects With Acute Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Candida Vulvovaginitis
Interventions: DRUG: Fluconazole|DRUG: SCY-078
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery
Status: TERMINATED
Conditions: Degenerative Disc Disease|Spinal Stenosis|Spondylosis|Spondylolisthesis
Interventions: OTHER: ViviGen Cellular Bone Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of SYN115 in Parkinson's Patients Using Levodopa to Treat End of Dose Wearing Off
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Tozadenant (SYN115) 60 mg BID|DRUG: Placebo|DRUG: Levodopa (L-dopa)|DRUG: Tozadenant (SYN115) 120 mg BID|DRUG: Tozadenant (SYN115) 180 mg BID|DRUG: Tozadenant (SYN115) 240 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab in Combination With Bortezomib and Dexamethasone in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma and Severe Renal Impairment
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Vascular Inflammation in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: sputum, blood, urine, exhaled breath, lung function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain Metastases
Status: COMPLETED
Conditions: Metastatic Cancer
Interventions: DRUG: temozolomide|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma|FGFR2 Gene Mutation|FGFR2 Gene Rearrangement|FGFR2 Gene Translocation
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CyberKnife Dose Escalation Prostate Cancer Trial
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Prostate Neoplasm
Interventions: RADIATION: CyberKnife SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Ketamine Administration in Patients With Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DEVICE: Extra-Corporal Life Support (ECLS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and effectivenesS in Adult KorEaN Patients Treated With Tolvaptan for Management of Autosomal domInAnt poLycystic Kidney Disease
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pediatric Very High-risk Acute Lymphoblastic Leukemia in Korea
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: DRUG: Dasatinib(Sprycel) arm|DRUG: Non-Dasatinib(Sprycel) arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HRS-9057 in Patients With Heart Failure and Volume Overload
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Volume Overload
Interventions: DRUG: HRS-9057|DRUG: HRS-9057|DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Time Interval Elimination on Pain Control of Preterm Infants by Sucrose Administration
Status: COMPLETED
Conditions: Neonatal Disease|Pain, Acute
Interventions: PROCEDURE: 2-minute-time interval of per oral 24% sucrose|PROCEDURE: no time interval of per oral 24% sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Camouflaged Dental Syringe
Status: NOT_YET_RECRUITING
Conditions: Anxiety, Dental|Behavior
Interventions: OTHER: The buccal infiltration anesthesia with a camouflaged dental syringe (Angelus ™)|OTHER: The buccal infiltration anesthesia with a conventional dental syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects
Status: COMPLETED
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: Levodopa carbidopa intestinal gel (LCIG)|DRUG: Placebo gel|DRUG: Levodopa carbidopa (LC) oral encapsulated immediate release (IR) tablets|DRUG: Placebo (PBO) oral capsules|DEVICE: CADD-Legacy® 1400 ambulatory infusion pump|DEVICE: PEG tube|DEVICE: J-tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy
Status: RECRUITING
Conditions: Sarcoma,Soft Tissue
Interventions: COMBINATION_PRODUCT: Pre-operative radiotherapy followed by 2 cycles of atezolizumab then surgery|COMBINATION_PRODUCT: 2 cycles of atezolizumab followed by surgery then post-operative radiotherapy|COMBINATION_PRODUCT: Pre-operative radiotherapy followed by surgery then 2 cycles of atezolizumab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Neutralizing Antibody in Healthy Participants
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: BGB DXP593|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination
Status: COMPLETED
Conditions: Endoscopy
Interventions: DRUG: Clear fluids|DRUG: Picosalax|DRUG: Polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CBSM Intervention Via mHealth to Ameliorate HIV-related Fatigue
Status: COMPLETED
Conditions: HIV|Stress Disorder|Human Immunodeficiency Virus|Fatigue
Interventions: BEHAVIORAL: CBSM-SMI|BEHAVIORAL: CBSM-SMI control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Intubated with Sevoflurane (IS)|DRUG: Intubated with Propofol (IP)|DRUG: Zofran - no intubation|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy Given With Amifostine and Filgrastim in Treating Patients With Recurrent or Metastatic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of the Reactogenicity, Safety and Immunogenicity of the Flu-M Vaccine Manufactured by FSUE SPbSRIVS FMBA
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-M [Inactivated split influenza vaccine]|BIOLOGICAL: Inactivated influenza split vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Anesthesia in Total Hip Arthroplasty
Status: TERMINATED
Conditions: Total Hip Arthroplasty
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementation of a Sexual Health Intervention for Young Men Who Have Sex With Men (MSM) in Two Vietnamese Cities
Status: COMPLETED
Conditions: HIV|Chlamydia|Gonorrhea|Syphilis|Hepatitis C
Interventions: BEHAVIORAL: Sexual Health Promotion Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Annexin A3 (ANXA3) as Protein-Based Marker for Non-Invasive Molecular Diagnostics of Prostate Carcinoma
Status: UNKNOWN
Conditions: Prostate Cancer|Benign Prostatic Hyperplasia|Prostatic Intraepithelial Neoplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VX-950-TiDP24-C133 - A Phase I Study Investigating the Interaction Between Telaprevir and Escitalopram
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir; Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MORAb-009 in Subjects With Pancreatic Cancer, Mesothelioma, or Certain Types of Ovarian or Lung Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Mesothelioma|Ovarian Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: MORAb-009
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of the BiTE® Blinatumomab (MT103) in Patients With Minimal Residual Disease of B-precursor Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Blinatumomab (MT103)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT