pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Status: RECRUITING
Conditions: Post-COVID Conditions|Obesity
Interventions: BEHAVIORAL: 12-weeks of Weight Loss|BEHAVIORAL: 12-weeks of Weight Stability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BI 1356 BS (Linagliptin) in Combination With Metformin in Patients With type2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Linagliptin|DRUG: Linagliptin|DRUG: Linagliptin|DRUG: Placebo|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical And Cost- Effectiveness of Allium Sativum Oil (Garlic Oil ) Versus Mineral Trioxide Aggregate in Primary Molars Pulpotomy in Group of Egyptian Children : A Randomised Clinical Pilot Study.
Status: UNKNOWN
Conditions: Carious Primary Molars
Interventions: DRUG: Allium Sativum Oil|DRUG: Mineral Tri-Oxide Aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial to Investigate Possible Drug-drug Interactions Between Clobazam and Cannabidiol
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: GWP42003-P 20 mg/kg/Day Dose|DRUG: Placebo|DRUG: Clobazam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
Status: COMPLETED
Conditions: Opioid Use
Interventions: DRUG: Celecoxib|DRUG: Acetaminophen|DRUG: Pregabalin|DRUG: Oxycodone|DRUG: Percocet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Effects on Skin Hyper Pigmentation With and Without Mesenchymal Stem Cell Enriched Adipose Tissue Grafting for "Contour Deformities With Pigmentary Changes on Face"
Status: UNKNOWN
Conditions: Skin Pigmentation Over Contour Deformities of Face|Trauma, Rhomberg Disease
Interventions: DRUG: MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer
Status: TERMINATED
Conditions: Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites|Malignant Neoplasms of Lip Oral Cavity and Pharynx|Oropharyngeal Cancer
Interventions: DRUG: Utomilumab|BIOLOGICAL: ISA101b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells for Ischemic Stroke
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: MSC Infusion|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Healthy Adults
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Inactivated Vaccine|BIOLOGICAL: The SARS-CoV-2 Inactivated Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects
Status: COMPLETED
Conditions: Pulmonary Alveolar Proteinosis|Bronchiectasis|Cystic Fibrosis|Acute Respiratory Distress Syndrome
Interventions: DRUG: Molgramostim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation
Status: UNKNOWN
Conditions: Pulmonary Emphysema|COPD|Lung Diseases
Interventions: DEVICE: AeriSeal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno-stimulation With Maraviroc Combined to Antiretroviral Therapy in Advanced Late Diagnosed HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV-1 Infection|AIDS
Interventions: DRUG: Maraviroc (Celsentri)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Community Health Worker-led Hypertension Management
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: OTHER: CommCare with Mobile Clinical Decision Support (CDS) Application|OTHER: Remote Supervision by Physicians|OTHER: CommCare Application without CDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gemcitabine Combined With Mistletoe in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer|Pancreatic Cancer
Interventions: DIETARY_SUPPLEMENT: mistletoe extract|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Omalizumab (CMAB007 and Xolair) in Healthy Subjects to Compare the PK, PD, Safety and Immunogenicity
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: CMAB007|BIOLOGICAL: Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Geriatric and Oncological Evaluation With Technology for Holistic Healthcare Management for Older Multimorbid Patients.
Status: WITHDRAWN
Conditions: Geriatrics|Medical Oncology|Critical Pathways|Digital Technology
Interventions: OTHER: Health Professional Consortium|DEVICE: Holis Dashboard - Holis Patient App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Metastatic Neuroendocrine Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Magnetic Resonance Imaging|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Replacement Therapy on the Postmenopausal Endometrium
Status: COMPLETED
Conditions: Menopause
Interventions: PROCEDURE: Endometrial Biopsy|DEVICE: Transvaginal Ultrasound|PROCEDURE: Endometrial Immunohistochemical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus Infection of the Upper Respiratory Tract
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: DRUG: Presatovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation Treatment of Renal Colic
Status: COMPLETED
Conditions: Renal Colic
Interventions: DEVICE: TENS|DEVICE: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Looking for Minimum Dose to Induce Sympathectomy in Infraclavicular Brachial Plexus Block
Status: UNKNOWN
Conditions: Finding the Minimum Dose to Induce Sympathectomy in Infraclavicular
Interventions: PROCEDURE: Infraclavicular brachial plexus block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Ischemic Preconditioning in Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Subarachnoid Hemorrhage|Cerebral Vasospasm|Intracranial Aneurysm
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement
Status: COMPLETED
Conditions: Atrial Fibrillation|Rheumatic Heart Disease
Interventions: PROCEDURE: surgical prevention of atrial fibrillation|DEVICE: cardiomonitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: iodixanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Effect of Probiotic Streptococcus Salivarius K12 Against Recurrent Streptococcus Pyogenes Pharyngotonsillitis Infection in Pediatrics
Status: NOT_YET_RECRUITING
Conditions: Streptococcus Pyogenes Pharyngotonsillitis
Interventions: DIETARY_SUPPLEMENT: Probiotic Bactoblis® (Streptococcus salivarius K12)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Remote Glucose Monitoring in Hospital Settings
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Hyperglycemia Stress|Hypoglycemia
Interventions: DEVICE: Real-Time CGM|DEVICE: Capillary blood glucose testing with masked CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain, Acute|Shoulder Pain
Interventions: PROCEDURE: intercostobrachial nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
Status: COMPLETED
Conditions: Denture Retention
Interventions: DEVICE: Denture Adhesive Cream (Conventional Application)|DEVICE: Denture Adhesive (Continuous Strip Application)|OTHER: No Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sustaining Remission of Psychotic Depression
Status: COMPLETED
Conditions: Psychotic Depression
Interventions: DRUG: Sertraline + Olanzapine|DRUG: Sertraline + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tricaprilin Phase 3 AD Study
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Tricaprilin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: DEVICE: MitraClip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Efficacy and Safety of QazCovid-in® COVID-19 Vaccine
Status: COMPLETED
Conditions: Covid19|SARS-CoV Infection|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: QazCovid-in®-vaccine against COVID-19|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Energy Drink Brands on Heart Rhythm
Status: COMPLETED
Conditions: Electrical Alternation of Heart|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Energy Drink Brand 1|DIETARY_SUPPLEMENT: Energy Drink Brand 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of GH on the Blastocyst Euploid Rate in AMA Patients
Status: RECRUITING
Conditions: Preimplantation Genetic Testing|Growth Hormone|Age, Parental
Interventions: DRUG: Growth Hormone|DRUG: GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional Bleomycin Versus Cryotherapy for Treatment of Cutaneous Warts
Status: COMPLETED
Conditions: Cutaneous Warts
Interventions: DRUG: Bleomycin Injection|PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics, With Target Occupancy Study of BIIB113 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BIIB113|DRUG: BIIB113-Matching Placebo|DRUG: 11^C]BIO-1819578
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus
Status: UNKNOWN
Conditions: Infective Endocarditis
Interventions: DRUG: Levofloxacin|DRUG: Rifampicin|PROCEDURE: Conventional IV treatment of staphylococci IE following European guidelines 2015 including cloxacilline, oxacilline,gentamicine,vancomycine,rifampicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Flutamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Monitoring and Data Acquisition and Utilization in Patients With Type 2 Diabetes Treated With Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Remote Blood Glucose Monitoring|OTHER: Continuous Glucose Monitoring|OTHER: SMBG|OTHER: SMBG With Knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 3 Clinical Trial of Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2(Trafermin)
Status: COMPLETED
Conditions: Periodontitis|Alveolar Bone Loss|Periodontal Attachment Loss
Interventions: DRUG: Trafermin (genetical recombination)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures
Status: COMPLETED
Conditions: Focal Onset Seizure|Focal Onset Epilepsy
Interventions: DRUG: NBI-921352|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Prevention of Osteoporosis in Premenopausal and Newly Postmenopausal (Up to 8 Years) Women With Breast Cancer Following Chemotherapy (REBBeCA Study)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: risedronate (including placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evidence for Potassium Restriction in Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: Hyperkalemia, Diminished Renal Excretion
Interventions: BEHAVIORAL: Novel dietary approach focused on restricting the intake of highly bioavailable potassium|BEHAVIORAL: Traditional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Alternating Current Stimulation Prevents Delirium in Patients With Subarachnoid Hemorrhage
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage
Interventions: DEVICE: Real transcranial alternating electrical stimulation|DEVICE: Sham transcranial alternating electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TDSM- Testosterone Dose Response in Surgically Menopausal Women
Status: COMPLETED
Conditions: Hysterectomy|Ovariectomy|Menopause|Testosterone Deficiency
Interventions: DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Anti Nausea Drugs Droperidol and Ondansetron on the Way the Heart Recovers Between Beats
Status: COMPLETED
Conditions: Myocardial Repolarization
Interventions: DRUG: droperidol and saline|DRUG: ondansetron and saline|DRUG: droperidol and ondansetron|DRUG: saline and saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of MK0859 on Lipoprotein Metabolism in Patients With Dyslipidemia (0859-026 AM3)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: anacetrapib|DRUG: Comparator: atorvastatin|DRUG: Comparator: placebo to MK0859|DRUG: Comparator: placebo to atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP
Status: NOT_YET_RECRUITING
Conditions: Sexually Transmitted Diseases, Bacterial
Interventions: DRUG: Doxycycline Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients
Status: COMPLETED
Conditions: Asthma|Asthma in Children
Interventions: DIAGNOSTIC_TEST: Vivatmo pro FeNO Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suitability of DCE-MRI for Detection of Vascular Changes After VBT
Status: COMPLETED
Conditions: Carcinoma of the Cervix, Carcinoma or Carcinosarcoma of the Uterus
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Selinexor|DRUG: Cladribine|DRUG: G-CSF|DRUG: Cytarabine|PROCEDURE: Bone marrow biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: diquafosol tetrasodium (INS365) ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Aromatase Inhibitors|Postmenopausal
Interventions: BEHAVIORAL: Combined Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases
Status: UNKNOWN
Conditions: Colon Cancer Liver Metastasis
Interventions: BIOLOGICAL: NKR-2 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-Randomized Study of the NightHawk Peripheral Plaque Excision System During Plaque Excision of Peripheral Arterial Disease
Status: TERMINATED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: NightHawk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium As a Treatment to Prevent Impairment of Cognition in Elders
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Myrcludex B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis
Status: RECRUITING
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: co-administration of cefepime and nacubactam|DRUG: co-administration of aztreonam and nacubactam|DRUG: imipenem/cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SCB-2019 as COVID-19 Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SCB-2019|BIOLOGICAL: SCB-2019 with AS03 adjuvant|BIOLOGICAL: SCB-2019 with CpG 1018 adjuvant plus Alum adjuvant|BIOLOGICAL: SCB-2019 with Alum adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo
Status: RECRUITING
Conditions: NIDDM|Obesity
Interventions: DRUG: Metformin Extended Release (ER) Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tomosynthesis as Primary Test for Breast Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: tomosynthesis + synthetic 2D|DIAGNOSTIC_TEST: digital mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: HIV Risk Reduction and Drug Abuse Treatment in Iran
Status: WITHDRAWN
Conditions: Opiate Dependence|HIV Infections
Interventions: DRUG: Buprenorphine/Subutex|DRUG: Naltrexone|BEHAVIORAL: Drug counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of VELCADE (Bortezomib) in Patients With Relapsed Follicular Lymphoma
Status: COMPLETED
Conditions: Relapsed Follicular Lymphoma
Interventions: DRUG: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: VELCADE|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Frequency rTMS Over l-DLPFC in Gambling Disorder
Status: UNKNOWN
Conditions: Gambling Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
Status: RECRUITING
Conditions: PTSD|Suicidal Ideation|Suicide, Attempted|Trauma, Psychological
Interventions: BEHAVIORAL: Prolonged exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbial Efficacy of ISV403 in Bacterial Conjunctivitis
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: ISV-403|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Feasibility Trial of the Fearon Algorithm to Improve Management of Unstable Warfarin
Status: TERMINATED
Conditions: Hypoprothrombinemia
Interventions: OTHER: Warfarin adjustment using the Fearon algorithm|OTHER: Warfarin adjustment using standard dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Foot Bath on Postoperative Sleep Quality and Pain
Status: COMPLETED
Conditions: Nursing Caries|Pain, Postoperative|Sleep Deprivation
Interventions: OTHER: Hot Foot Bath 1|OTHER: Hot Foot Bath 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Albuferon and Ribavirin in Interferon Naive Subjects With Chronic Hepatitis C Genotype 1
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Albuferon|DRUG: Ribavirin|DRUG: PEG-IFNalfa2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of an Adapted DBT-informed Skills Group for Gender Diverse Young People Co-delivered in a Charity Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Emotional Regulation
Interventions: BEHAVIORAL: Dialectical behavioural therapy (DBT)-informed skills group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancers.
Interventions: RADIATION: Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Need of Needle Change for Application of Intramuscular, Subcutaneous and Intradermal Injection.
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice|Injection Site Reactions
Interventions: DEVICE: needle exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Benefit of Cheyne-Stokes Respiration Remote Monitoring in CPAP-treated Patients With Obstructive Sleep Apnea to Detect Early Events of Heart Failure.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: CSR remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Physical Activity Coaching in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Physical Activity|Health Behavior
Interventions: BEHAVIORAL: Telephonic health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PromotinG Lung Cancer screenIng Awareness and Implementation in Hispanics/Latinx Head and Neck canceR Survivors
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Lung Cancer Screening Education|BEHAVIORAL: Semi-Structured Interview|BEHAVIORAL: Standard of Care Lung Cancer Screening Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of Different Boosting Agents on Pharmacokinetics of BILR 355 BS Dissolved in Polyethylene Glycol 400 (PEG 400) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 BS|OTHER: Grapefruit juice|DRUG: Nelfinavir|DRUG: Atazanavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions
Status: COMPLETED
Conditions: CABG-Patients
Interventions: PROCEDURE: Determination of neuropsychological status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating Inotuzumab Ozogamicin (CMC-544) In Indolent Non-Hodgkins Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Inotuzumab Ozogamicin (CMC-544)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Plantar Sensory Exercises on Balance and Fall Risk in Nursing Home Elderly
Status: COMPLETED
Conditions: Balance; Distorted|Plantar|Falling|Elderly|Sensitivity
Interventions: OTHER: plantar sensory exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Parenteral Emulsion With Omega3 on Neonates With PPHN and CDH
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Hypertension of Newborn|Diaphragm Defect
Interventions: COMBINATION_PRODUCT: lipid injectable emulsion with Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine Administered 6 Years Post-MenC Primary Vaccination in Healthy Subjects Who Were 12-18 Months at Primary Vaccination
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal conjugate vaccine GSK134612
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Increasing Adherence to Lung Cancer Screening
Status: RECRUITING
Conditions: Lung Cancer|Adherence, Patient
Interventions: BEHAVIORAL: Patient Nudge|BEHAVIORAL: Clinician Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing A New Drug Containing The Combination Meloxicam And Cyclobenzaprine In The Treatment Of Acute Lumbago
Status: WITHDRAWN
Conditions: Acute Lumbago
Interventions: DRUG: meloxicam/cyclobenzaprine hydrochloride|DRUG: meloxicam - Movatec®|DRUG: cyclobenzaprine - Miosan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Resolution Solid-State Manometry of the Effect of Succinylcholine on Barrier Pressure
Status: COMPLETED
Conditions: the Effect of Succinylcholine on Barrier Pressure
Interventions: DRUG: Succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Antibiotic-Associated Diarrhoea With Prolardii
Status: UNKNOWN
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Prolardii|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Demonstrate the Bioequivalence of Interferon Beta-1a (INFB) Manufactured by Two Different Processes in Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a (current approved manufacturing process invloving FBS)|DRUG: Interferon beta-1a (new process, manufactured without FBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Dextroamphetamine-Cocaine Behavioral Intervention - 5
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Dextroamphetamine|DRUG: D-amphetamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bermekimab for the Treatment of Participants With Moderate to Severe Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Bermekimab|DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Nasopharyngeal Carcinoma (NPC) Treated With Celecoxib And ZD1839
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: celecoxib, gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (HARMONY) Study of BLU-701 in EGFR-mutant NSCLC
Status: TERMINATED
Conditions: Lung Neoplasm|Carcinoma, Non-Small-Cell Lung|Respiratory Tract Neoplasms|Neoplasms|Neoplasms by Site|Lung Diseases|Respiratory Tract Diseases|Carcinoma, Bronchogenic|Bronchial Neoplasms|Adenocarcinoma|Carcinoma|Neoplasms by Histologic Type|Neoplasms, Nerve Tissue|EGFR C797S|EGFR C797A|EGFR L858R|EGFR Exon 19 Deletion|EGFR Gene Mutation|EGF-R Positive Non-Small Cell Lung Cancer|EGFR Mutation Resulting in Tyrosine Kinase Inhibitor Resistance|EGFR Activating Mutation|Thoracic Neoplasms|Antineoplastic Agents|Protein Kinase Inhibitors|EGFR C797G|EGFR C797X|Non Small Cell Lung Cancer
Interventions: DRUG: BLU-701|DRUG: osimertinib|DRUG: carboplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
Status: RECRUITING
Conditions: Cutaneous Lupus Erythematosus (CLE)
Interventions: DRUG: Edecesertib|DRUG: Edecesertib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Follow up Study of Intramuscular Olanzapine Depot in Patients With Schizophrenia or Schizoaffective Disorder
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorders
Interventions: DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Efficacy and Safety Between Short-term Continuous Subcutaneous Beinaglutide Injection and Continuous Subcutaneous Insulin Infusion (CSII) for Newly Diagnosed Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetic Patients
Interventions: DRUG: Beinaglutide|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentafecta Outcomes After Robot-assisted Laparoscopic Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer|Erectile Dysfunction|Complication of Surgical Procedure|Urinary Incontinence
Interventions: PROCEDURE: Robot-assisted laparoscopic radical prostatectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: RECRUITING
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: NCX 470 0.1%|DRUG: Latanoprost 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ATG in HLA-matched Sibling HSCT as GVHD Prophylaxis
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: ATG|DRUG: CsA|DRUG: MTX|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Safety of 0.005 % Estriol Vaginal Gel in Hormone Receptor-Positive Postmenopausal Women With Early Stage Breast Cancer in Treatment With Aromatase Inhibitor in the Adjuvant Setting
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: estriol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GLPG1205 in Subjects With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: GLPG1205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Inflammatory Mechanisms in Epidermolysis Bullosa Simplex- Dowling Meara
Status: COMPLETED
Conditions: Epidermolysis Bullosa Simplex Dowling Meara
Interventions: PROCEDURE: Taking of liquid and top of blisters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of A Mobile-Bearing Total Knee System With A Fixed-Bearing Total Knee System In Cemented Total Knee Arthroplasty
Status: COMPLETED
Conditions: Degenerative Joint Disease
Interventions: DEVICE: Sigma Knee System|DEVICE: Sigma Pressfit Condylar Posterior Cruciate Substituting System with a metal back tibial tray|DEVICE: Sigma Pressfit Condylar Posterior Cruciate Substituting System all polyethylene tray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: "Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".
Status: COMPLETED
Conditions: Rectal Cancer, Adenocarcinoma|Rectal Cancer Stage II|Rectal Cancer Stage III|Distant Metastasis|Local Recurrence of Malignant Tumor of Rectum
Interventions: PROCEDURE: neoadjuvant treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Shade Evaluation of Monochromatic Versus Polychromatic Layering Techniques Inrestoration of Fractured Incisal Angle
Status: UNKNOWN
Conditions: Anterior Teeth
Interventions: OTHER: (3M™ Filtek™ Universal )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of the Effect of Highland Barley Diet on Blood Glucose in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Highland Barley Diet|DIETARY_SUPPLEMENT: ADA diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SG301 Safety Study in Subjects With Relapsed or Refractory Multiple Myeloma and Other Hematological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma|Hematological Malignancy
Interventions: DRUG: SG301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FSH-GEX™ in Comparison With 150 IU Gonal-f®
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Follitropin Epsilon|DRUG: Follitropin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD1446 Administered for 4 Weeks in Elderly Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1446|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics Study of Famitinib Malate Capsules in Healthy Subjects
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Famitinib Malate Capsules|DRUG: Famitinib Malate Capsules|DRUG: Famitinib Malate Capsules|DRUG: Famitinib Malate Capsules|DRUG: Famitinib Malate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 3 Study to Evaluate the Immunogenicity and Safety of Inactivated Split Influenza Vaccine in Healthy Korea Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: IL-YANG FLU Vaccine Prefilled Syringe INJ 0.5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry Eye
Status: RECRUITING
Conditions: Dry Eye
Interventions: DRUG: artificial tear eyedrops|DRUG: 0.05% cyclosporine eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAINT for Treatment of Preoperative Depression to Reduce Opioid Use Following Arthroplasty
Status: WITHDRAWN
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Active TBS-DLPFC|DEVICE: Sham TBS-DLPFC|DEVICE: Open label TBS-DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Computed Tomography Myocardial Perfusion Imaging for Detection of Coronary Artery Disease
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Ischemia
Interventions: DIAGNOSTIC_TEST: Computed Tomography Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: 10-1074-LS|DRUG: 10-1074-LS|DRUG: 3BNC117-LS|DRUG: 3BNC117-LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does Timing of VT Ablation Affect Prognosis in Patients With an Implantable Cardioverter-defibrillator?
Status: UNKNOWN
Conditions: Ventricular Tachycardias
Interventions: PROCEDURE: Immediate radiofrequency ablation of ventricular tachycardia|PROCEDURE: Radiofrequency ablation of ventricular tachycardia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Retrospective International Survey to Evaluate the Rate of AXIOS-related AEs in Endoscopic Transmural Drainage of Pancreatic Fluid Collections
Status: COMPLETED
Conditions: Endoscopic Transmural Drainage of Pancreatic Fluid Collections
Interventions: OTHER: The use of AXIOS in Endoscopic transmural drainage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Training and Dual-task Ability
Status: COMPLETED
Conditions: Gait Disorder
Interventions: BEHAVIORAL: Balance rehabilitation + dual-tasking|BEHAVIORAL: Standard balance rehabilitation|BEHAVIORAL: Cognitive training (speed of processing)|BEHAVIORAL: Cognitive training (general cognition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Diagnostic Yield Using a Robotic Navigational Bronchoscopy System With CBCT
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Biopsy with the Robotic- Ion Endoluminal System with Adjunct Real-time Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC