pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy and Safety of "BST104" (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects
Status: COMPLETED
Conditions: Functional Dyspepsia|Irritable Bowel Syndrome
Interventions: DRUG: BST-104 (Lonicera Flos Extract)|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features
Status: COMPLETED
Conditions: Pre-Eclampsia|HELLP Syndrome|Eclampsia
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Short-chain Fatty Acids in Malnutrition on Stress, Eating Behavior, and Nutritional State
Status: NOT_YET_RECRUITING
Conditions: Anorexia Nervosa
Interventions: OTHER: Short-chain fatty acids (SCFAs)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Oral Dexamethasone Doses in Asthma Exacerbation
Status: COMPLETED
Conditions: Asthma|Reactive Airway Disease
Interventions: DRUG: Dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Percutaneous Intervention Performed With Devices of a Single-brand
Status: COMPLETED
Conditions: Atherosclerotic Heart Disease|Coronary Heart Disease
Interventions: DEVICE: Coronary stent - Tsunami
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Release Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disseminating Effective Habits for Long-Term Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Disseminating Effective Habits for Long-term Weight Loss|BEHAVIORAL: Achieve Together website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seoul National University Pituitary Disease Cohort Study
Status: RECRUITING
Conditions: Pituitary Disease|Pituitary Incidentaloma|Acromegaly|Central Diabetes Insipidus|Pituitary Stalk Compression Hyperprolactinaemia|Cushing's Disease|Pituitary Tumor|Prolactinoma
Interventions: OTHER: Dynamic hormone study and Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CANNAbinoids in the Treatment of TICS (CANNA-TICS)
Status: COMPLETED
Conditions: Tourette Syndrome|Tic Disorders
Interventions: DRUG: nabiximols|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath
Status: ACTIVE_NOT_RECRUITING
Conditions: E-cigarette Use
Interventions: BEHAVIORAL: CATCH My Breath (CMB) program for E-cigarette prevention among adolescents|BEHAVIORAL: Texas Education Agency (TEA) required tobacco prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TONEFITreha: Proof of Concept and Usability Study.
Status: COMPLETED
Conditions: Neurological Disorder|Orthopedic Disorder
Interventions: DEVICE: TONEFITreha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Pharmacokinetics of Nifedipine Controlled Release Tablets in Hypertensive Patients on Hemodialysis
Status: UNKNOWN
Conditions: Hypertension on Chronic Maintenance Hemodialysis
Interventions: DRUG: nifedipine controlled release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: S0342: Paclitaxel, Carboplatin, and Cetuximab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cetuximab|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: AMR101 (ethyl icosapentate) - 4 g/day|DRUG: AMR101 (ethyl icosapentate) - 2 g/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing UTIs in Chronic Neurogenic Bladder Dysfunction (Mix Methods)
Status: COMPLETED
Conditions: UTI|Neurogenic Bladder|Antibiotic Resistance
Interventions: DRUG: Uro vaxom|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004
Status: COMPLETED
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Dexamethasone|DRUG: Etoposide|DRUG: Cyclosporin|PROCEDURE: Intrathecal therapy|PROCEDURE: Stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumoperitoneum Management With SurgiQuest AirSeal® at Low vs. Higher Pressure
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain
Interventions: DEVICE: AirSeal® Insufflation System (AIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma (DIPG)
Interventions: DRUG: Melphalan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AK002 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AK002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remifentanil on Postoperative Vomiting in Pediatric Strabismus Surgery
Status: COMPLETED
Conditions: Strabismus
Interventions: DRUG: High dose remifentanil|DRUG: Low dose remifentanil|DRUG: No remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: BEHAVIORAL: Early START visit using checklist over telephone or zoom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Biofeedback Tools to Train the Transversus Abdominis Activation in Healthy Subjects
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Real-time ultrasound imaging feedback|DEVICE: PBU feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIL62 Plus Lenalidomide for Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (FL and MZL)
Status: RECRUITING
Conditions: Follicular Lymphoma and Marginal Zone Lymphoma
Interventions: DRUG: Recombinant Humanized Monoclonal Antibody MIL62 Injection|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect, Spinal and Epidural|Hypotension|Complications; Cesarean Section
Interventions: DRUG: Norepinephrine|DRUG: Ephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MSB11456 in Participants With Moderately to Severely Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MSB11456|DRUG: EU-approved RoActemra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia
Status: COMPLETED
Conditions: β-thalassemia|Ineffective Erythropoiesis|Chronic Anemia
Interventions: DRUG: PTG-300
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Virtual Reality Patients With Obstetric Brachial Plexus Injury
Status: COMPLETED
Conditions: Obstetric Brachial Plexus Injury
Interventions: OTHER: Virtual reality treatment|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Relapsed B-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Loncastuximab Tesirine|DRUG: Polatuzumab Vedotin|DRUG: Glofitamab|DRUG: Mosunetuzumab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Control lenses|DEVICE: Test lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Thrombopoietin (rhTPO) in Management of Immune Thrombocytopenia (ITP) in Pregnancy
Status: UNKNOWN
Conditions: Immune Thrombocytopenia|Pregnancy
Interventions: DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hip Arthroscopy Postoperative Opioid Demands
Status: RECRUITING
Conditions: Opioid Use|Pain|Femoral Acetabular Impingement|Labral Tear, Glenoid
Interventions: OTHER: Control Group Regimen|OTHER: Opioid reduced regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Predictive Role of Proteomics in Blood Pressure Response of Hypertensive Patients Undergoing Renal Denervation.
Status: RECRUITING
Conditions: Hypertension|Renal Denervation|Proteomics
Interventions: DIAGNOSTIC_TEST: Urine sample for proteomic analysis|DIAGNOSTIC_TEST: ABPM|DIAGNOSTIC_TEST: OBPM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics And Relative Bioavailability Of Bococizumab (PF-04950615; RN316) When Administered To The Abdomen, Thigh Or Upper Arm
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BIOLOGICAL: Bococizumab (PF-04950615; RN316)|BIOLOGICAL: Bococizumab (PF-04950615; RN316)|BIOLOGICAL: Bococizumab (PF-04950615; RN316)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Evaluate the Lot-to-lot Consistency of Live Attenuated Varicella Vaccine in Healthy People 1-12 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Varicella
Interventions: BIOLOGICAL: Investigational live attenuated varicella vaccine (lot 1)|BIOLOGICAL: Investigational live attenuated varicella vaccine (lot 2)|BIOLOGICAL: Investigational live attenuated varicella vaccine (lot 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Evaluating the Duration of Efficacy of One Intra Articular Injection of Sodium Hyaluronate 2.0% in Patients With Painful Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis Patient
Interventions: DRUG: Ostenil plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Keto Drinks as a Meal Primer in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Ketoses, Metabolic
Interventions: DIETARY_SUPPLEMENT: 3-hydroxybutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Ultrasound With Lumason in Detecting Liver Cancer in Participants With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: PROCEDURE: Contrast-Enhanced Ultrasound|DRUG: Sulfur Hexafluoride Lipid Microspheres|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Effect of Anterior Subcutaneous and Submuscular Transposition on Cubital Tunnel Syndrome
Status: COMPLETED
Conditions: Cubital Tunnel Syndrome
Interventions: PROCEDURE: anterior subcutaneous transposition|PROCEDURE: Anterior submuscular transposition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation Regimens in GI Endoscopy
Status: COMPLETED
Conditions: Anesthesia|Endoscopy|Colonoscopy|Conscious Sedation
Interventions: DRUG: midazolam alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Switching From a First- or Second-line Disease Modifying Therapy (DMT) to Ozanimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fetal Thymus Volume of Dichorionic Diamniotic Twin
Status: COMPLETED
Conditions: Twin Pregnancy, Antepartum Condition or Complication|Fetal Thymus Volume|Preterm Birth
Interventions: OTHER: assesment of thymus volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Role of Vitamin D3 in Pediatric Bronchiectasis Severity
Status: COMPLETED
Conditions: Cystic Fibrosis and Non CF Bronchiectasis
Interventions: DRUG: Cholecalciferol (vitaminD3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of Non-pharmacological Techniques on Cognitive Complaints in Cancer Patients
Status: WITHDRAWN
Conditions: Non-Metastatic Neoplasm
Interventions: BEHAVIORAL: Self-hypnosis/self-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT
Status: COMPLETED
Conditions: Neisseria Gonorrhoeae Infection|Chlamydia Trachomatis Infection|Sexually Transmitted Infections
Interventions: DIAGNOSTIC_TEST: Nucleic acid amplification test 1 for NG and CT|DIAGNOSTIC_TEST: Nucleic acid amplification test 2 for NG and CT|DIAGNOSTIC_TEST: Nucleic acid amplification test 3 for NG and CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Harm Reduction With Pharmacotherapy (HaRP)
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: XR-NTX|OTHER: Placebo|BEHAVIORAL: HRC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: DRUG: Imipenem/Cilastatin/Relebactam|DRUG: Cefepime|DRUG: Meropenem|DRUG: Piperacillin-Tazobactam|DRUG: Vancomycin|DRUG: Daptomycin|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
Status: COMPLETED
Conditions: Lumbar Degenerative Disc Disease|Lumbar Spinal Stenosis|Lumbar Spondylolisthesis|Lumbar Spinal Deformity|Lumbar Spondylosis
Interventions: DEVICE: Interbody cage (titanium)|DEVICE: Interbody cage (PEEK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Freeze-dried Kale to Reduce Metabolic Risk in Saudi Subjects
Status: UNKNOWN
Conditions: Obesity|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Kale supplement|DIETARY_SUPPLEMENT: Peas supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SHR-1210 Plus Apatinib in Patients With Advanced-Stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: SHR-1210|DRUG: apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Recovery Using Multimodal Peri-operative Analgesia in Minimally Invasive Myomectomy
Status: COMPLETED
Conditions: Anesthesia|Myomectomy
Interventions: PROCEDURE: Multimodal analgesic protocol during minimally invasive myomectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Using Doxorubicin-eluting Beads for Patients With HCC and Marginal Hepatic Reserve
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Chemoembolization
Interventions: DEVICE: LC Bead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doravirine, Rifapentine and Isoniazid Interaction
Status: COMPLETED
Conditions: Latent Tuberculosis|Human Immunodeficiency Virus|Rifamycins Causing Adverse Effects in Therapeutic Use|Drug Interaction Potentiation
Interventions: DRUG: Doravirine (DOR)|DRUG: Rifapentine (RPT)|DRUG: Isoniazid (INH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Reactivity to Physical Stress
Status: RECRUITING
Conditions: Blood Pressure|Stress, Physiological
Interventions: OTHER: Low-volume high intensity exercise|OTHER: Combined intermittent sauna and cold water bath (sauna+cold bath).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Health Coaching for Chronic Multisymptom Illness
Status: RECRUITING
Conditions: Pain Predominant Chronic Multisymptom Illness
Interventions: BEHAVIORAL: Health Coaching|BEHAVIORAL: Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Infusion of DMF5 Cells to Treat Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma|Malignant Melanoma|Melanoma, Experimental
Interventions: DRUG: DMF5 Melanoma Reactive TIL|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Tolerability of Two FSH Preparations (Human FSH Versus rFSH - Follitropin Alpha) in Women Undergoing IVF
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: FSH-IBSA|DRUG: GONAL-F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Maintenance Treatment With Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)|Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: BIOLOGICAL: IgPro20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra: Efficacy in the Management of Fever During Neutropenia and Mucositis in ASCT - A Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Anakinra|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Usefulness of Nasal Continuous Positive Airway Pressure (CPAP) Treatment in Patients With a First Ever Stroke and Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea|Stroke|Cardiovascular Disease
Interventions: DEVICE: Nasal CPAP (Continuous Positive Airway Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of Increased Lymph Node Yield in Colorectal Cancer Patients With Synchronous Distant Metastasis: a Population-based Study of the US Database and a Chinese Registry
Status: COMPLETED
Conditions: Colorectal Cancer Stage IV|Lymph Node Yield
Interventions: OTHER: lymph node yield
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1-2a Dose-Ranging Study of TLK286 in Combination With Docetaxel in Platinum-Resistant Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: TLK286 in combination with docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Piloting an Avatar-based Intervention to Support Patients Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematopoietic Cell Transplantation
Interventions: BEHAVIORAL: Care.Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Severity-Adapted Clinical Trial of Diminished Bone Mineral Density in Acute Lymphoblastic Leukemia Survivors
Status: COMPLETED
Conditions: Leukemia, Lymphoblastic, Acute|Osteoporosis
Interventions: DRUG: Calcium carbonate (Tums), vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial With Bronchipret and Sinupret to Evaluate Acceleration of Mucociliary Clearance (MCC)
Status: COMPLETED
Conditions: Current Smokers
Interventions: DRUG: administration of Sinupret|DRUG: administration of Bronchipret|DRUG: administration of Sinupret Placebo|DRUG: administration of Bronchipret Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Diagnosis and Pathophysiology of Pulmonary Embolism (APE 1 Trial)
Status: TERMINATED
Conditions: Pulmonary Embolism|Right Heart Strain
Interventions: PROCEDURE: Scintigraphic interpretation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma
Status: TERMINATED
Conditions: Rhabdomyosarcoma|Rhabdomyosarcoma, Alveolar|Rhabdomyosarcoma, Embryonal
Interventions: DRUG: Dasatinib|DRUG: Dasatinib|DRUG: Ganitumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of [18F]FES PET/CT for Axillary LN Metastasis in Invasive Lobular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Lobular
Interventions: DRUG: [18F]fluoroestradiol (FES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Biphenotypic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome|Untreated Adult Acute Myeloid Leukemia
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Liposomal Cytarabine-Daunorubicin CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Betamethasone Microsphere in Patients With Macular Edema Following Branch Retinal Vein Occlusion (HIKARI)
Status: COMPLETED
Conditions: Macular Edema Following Branch Retinal Vein Occlusion
Interventions: DRUG: Betamethasone Microsphere (DE-102） Low Dose|DRUG: Betamethasone Microsphere (DE-102） High Dose|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss|Mydriasis|Cataract
Interventions: DRUG: Fydrane®: (Manufacturer DELPHARM TOURS, FRANCE).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cryoballoon Ablation of Pulmonary Veins After Failed RF Ablation in Patients With Paroxysmal AF
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: cryoballoon ablation|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Mixture of G, C and S in Treatment of Patients With RCC
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Gemcitabine, Capecitabine and Sorafenib (6 cycles)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin Treatment in Extremely Low Birth Weight Infants
Status: COMPLETED
Conditions: Infant, Low Birth Weight|Anemia
Interventions: DRUG: epoetin beta|DRUG: epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Versus Radiologic Biliary Drainage for Perihilar Malignant Obstruction
Status: UNKNOWN
Conditions: Perihilar Cholangiocarcinoma|Jaundice, Obstructive
Interventions: PROCEDURE: Endoscopic drainage|PROCEDURE: Percutaneous transhepatic biliary drainage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MEK and MET Inhibition in Colorectal Cancer
Status: COMPLETED
Conditions: Solid Tumor|Colorectal Cancer
Interventions: DRUG: PF-02341066|DRUG: PD-0325901|DRUG: Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Randomized, Placebo Controlled, Clinical Trial of an Antiplaque Chewing Gum (30 mg) - Phase 2 Proof of Concept in a Generally Healthy Patient Population
Status: COMPLETED
Conditions: Plaque Regrowth
Interventions: DRUG: KSL-W|DRUG: Chewing Gum Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Association of Insulin Resistance and FGF21 on Cardiac Function in Pediatric Dilated Cardiomyopathy
Status: TERMINATED
Conditions: Cardiomyopathy, Dilated|Cardiomyopathy, Hypertrophic|Insulin Resistance
Interventions: DIAGNOSTIC_TEST: Oral glucose tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mesenchymal Cell Therapy in Osteogenesis Imperfecta (OI)
Status: NOT_YET_RECRUITING
Conditions: Osteogenesis Imperfecta|Osteogenesis Imperfecta Type III
Interventions: DRUG: Bone marrow-derived mesenchymal stromal cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Clarithromycin/Rifampicin on the Pharmacokinetics of DA-8010 in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-8010 5mg|DRUG: Clarithromycin 500mg|DRUG: Rifampicin 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-NK Targeted CD19 for r/r B-cell Malignancies
Status: RECRUITING
Conditions: Adult Relapsed/Refractory B-cell Hematologic Malignancies
Interventions: BIOLOGICAL: CD19-CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Aldosteronism and Surgically Curable Forms in Hypertension Patients Using 11C-Metomidate
Status: COMPLETED
Conditions: Primary Aldosteronism|Primary Aldosteronism Due to Aldosterone Producing Adenoma
Interventions: COMBINATION_PRODUCT: 11C-Metomidate PET/CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: STA-5312 Administered on Alternate Weekdays Every Two Weeks to Patients With Hematologic Malignancies and Patients With Solid Tumors
Status: COMPLETED
Conditions: Hematological Malignancies|Leukemia|Lymphoma|Metastatic or Unresectable Solid Tumors
Interventions: DRUG: STA-5312
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Safety Guidewire Increase the Forces Needed to Move the Ureteroscope up and Down the Ureter?
Status: COMPLETED
Conditions: Ureteroscopy
Interventions: PROCEDURE: Ureteroscopy with and without safety guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia)
Status: COMPLETED
Conditions: Fibromyalgia|Interstitial Cystitis
Interventions: DEVICE: Intermittent Exposure to Oxygen via Oro-Nasal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Celecoxib as a Chemopreventive Agent in Current and Former Smokers
Status: COMPLETED
Conditions: Smoking|Prevention
Interventions: DRUG: Celecoxib|DRUG: Celecoxib|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
Status: COMPLETED
Conditions: Thyroid Neoplasms|Goiter, Nodular|Thyroid Nodule|Graves' Disease|Hyperparathyroidism
Interventions: PROCEDURE: Superficial Cervical Plexus Block|PROCEDURE: Local Wound Infiltration|DRUG: 0.9% saline|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Methadone in Hip Fracture Patients
Status: COMPLETED
Conditions: Methadone|Pain, Post Operative|Pain, Postoperative|Analgesics, Opioid
Interventions: DRUG: Methadone (Dose1)|DRUG: Methadone (Dose 2)|DRUG: Methadone (Dose 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Glucosamine Plus Diacerein Versus Mono-therapy of Glucosamine
Status: COMPLETED
Conditions: Osteoarthritis|Glucosamine|Diacerein
Interventions: DRUG: Glucosamine sulfate|DRUG: Diacerein|DRUG: Placebo (for Diacerein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I and Consecutive Phase II, Two-arm, Randomized Multi-center Trial in Patients With Advanced Melanoma
Status: UNKNOWN
Conditions: Advanced Melanoma
Interventions: DRUG: dacarbazine (DTIC), Trofosfamide, Etoricoxib, Pioglitazone, Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Therapeutic Effect of Laser Acupuncture in Patients With Acute or Subacute Post Stroke Shoulder Pain
Status: RECRUITING
Conditions: Post Stroke Shoulder Pain
Interventions: DEVICE: Verum laser acupuncture|DEVICE: Sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacology of KHK4827 in Healthy Volunteers and Subject With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: KHK4827
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: CATIE- Schizophrenia Trial
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: perphenazine|DRUG: olanzapine|DRUG: quetiapine|DRUG: risperidone|DRUG: ziprasidone|DRUG: clozapine|DRUG: fluphenazine decanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Music for Orbital Decompression
Status: UNKNOWN
Conditions: Surgery|Pain|Musth
Interventions: OTHER: Music|OTHER: Routine perioperative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing One-lung Ventilation for Lung Surgery
Status: COMPLETED
Conditions: Lung Cancer|One Lung Ventilation|Gas Exchange|Inverse-ratio Ventilation
Interventions: OTHER: Conventional I:E ratio|OTHER: I:E = 1:1 ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: HEM1036 Phase 2 Study in Low Anterior Resection Syndrome
Status: NOT_YET_RECRUITING
Conditions: LARS - Low Anterior Resection Syndrome
Interventions: DRUG: Lactobacillus Fermentum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimum Effective Volume of Local Anesthetic for Peribulbar Block.Does it Differ With the Eyeball Axial Length?
Status: COMPLETED
Conditions: Peribulbar Block
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DEVICE: Springfusor infusion pump|OTHER: IV administration|DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of ALKS 5461 in Healthy Subjects and Subjects With Hepatic Impairment and Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: ALKS 5461
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Status: COMPLETED
Conditions: Vitamin D Deficiency|Obesity|Diabetes Mellitus|Pre-Eclampsia|Arthritis|Asthma|Bone Fracture|Tooth Diseases|Birth Weight|Birth Disorder|Pregnancy Complications|Mental Disorder|Cancer|Congenital Disorders
Interventions: OTHER: D-tect
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beneficial Effect of Xylose Consumption on Postprandial Hyperglycemia
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Test 1|DIETARY_SUPPLEMENT: Test 2|DIETARY_SUPPLEMENT: Test 3|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of Food On How Tasocitinib (CP-690,550) Is Absorbed And Moves Through The Body Following Oral Administration Of Tasocitinib (CP-690,550) Tablets To Healthy Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment B|DRUG: Treatment A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of TK2 Deficiency With Thymidine and Deoxycytidine
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitochondrial DNA Depletion Syndrome 2 Myopathic Type|Thymidine Kinase 2 Deficiency
Interventions: DRUG: Thymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Learn About The Study Vaccine (Called Self-Amplifying Ribonucleic Acid (RNA)) For The Prevention of Influenza
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: PF-07852352 Influenza saRNA 1|BIOLOGICAL: PF-07836391 Influenza saRNA|BIOLOGICAL: PF-07836394 Influenza saRNA|BIOLOGICAL: PF-07836395 Influenza saRNA|BIOLOGICAL: PF-07836396 Influenza saRNA|BIOLOGICAL: PF-07867246 Influenza saRNA|BIOLOGICAL: Placebo|BIOLOGICAL: Quadrivalent influenza vaccine (QIV)|BIOLOGICAL: PF-07871987 Influenza saRNA|BIOLOGICAL: PF-07914705 Influenza saRNA|BIOLOGICAL: PF-07915048 Influenza saRNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study
Status: COMPLETED
Conditions: Body Dysmorphic Disorders|Anorexia
Interventions: DRUG: Positron Emission Tomography using [11C]diprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of PENG Associated With LFCN Block Versus FICB for Multimodal Analgesic Management in THA
Status: RECRUITING
Conditions: Regional Anesthesia Morbidity|Arthropathy of Hip|Hip Arthropathy|Post Operative Pain|Anesthesia Complication
Interventions: PROCEDURE: PENG plus LFCN block|PROCEDURE: FIC Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shingles Prevention Study
Status: COMPLETED
Conditions: Herpes Zoster|Postherpetic Neuralgia
Interventions: BIOLOGICAL: Varicella-zoster vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incidence, Prevalence, and Symptom Burden Associated With Advanced Renal Cell Carcinoma in Commercially Insured Population (Pharmetrics)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Targeted agents indicated in management of advanced/metastatic RCC (sunitinib, sorafenib, bevacizumab, and pazopanib)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19
Status: UNKNOWN
Conditions: Coronavirus|Coronavirus Infection|Severe Acute Respiratory Syndrome Coronavirus 2|Pneumonia|Pneumonia, Viral|Lung Diseases|Respiratory Tract Disease|Respiratory Tract Infections|Coronaviridae Infections|Nidovirales Infections|RNA Virus Infections|Virus Disease|Immunologic Disease|ARDS|Immunologic Factors|Physiological Effects of Drugs|Antiviral Agents|Anti-infective Agents|Analgesics|Antimetabolites, Antineoplastic
Interventions: BIOLOGICAL: CYNK-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Transdiagnostic Guided Internet-Delivered Intervention for Emotional, Trauma and Stress-Related Disorders.
Status: UNKNOWN
Conditions: Emotional Disorder|Trauma and Stressor Related Disorders|Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Transdiagnostic guided internet-delivered intervention with synchronous assistance|BEHAVIORAL: Transdiagnostic self-guided internet-delivered intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Influence of CKD-519 on 24-h Ambulatory Blood Pressure in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CKD-519 200mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic-assisted Upper Extremity Training in Spinal Cord Injury Patients
Status: COMPLETED
Conditions: Spinal Cord Injury Cervical
Interventions: PROCEDURE: Conventional Rehabilitation|PROCEDURE: Robotic REhabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Mobile Application in Improving Employees' Social Well-being.
Status: NOT_YET_RECRUITING
Conditions: Loneliness|Social Isolation|Social Support|Depressive Symptoms
Interventions: BEHAVIORAL: Frendie PRO mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Anaesthesia
Status: COMPLETED
Conditions: Anesthesia, Obstetric
Interventions: DRUG: DEXMEDETOMIDINE|DRUG: Neostigmine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinomas
Interventions: DRUG: PF regimen (cis-platinum ; 5-fluorouracil ) combined with PD-1 inhibitors（pembrolizumab）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, PK, and Efficacy of the Myc Inhibitor OMO-103 Administered iv in Patients With PDAC
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: OMO-103|DRUG: Nab-Paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DRUG: Oxytocin|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT