pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Status: COMPLETED
Conditions: Application Site Discomfort|Medical Device Discomfort
Interventions: DRUG: Bupivacaine with Epinephrine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natriuretic Effect of Telmisartan Versus Placebo in Patients With Mild-to-Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan, low dose|DRUG: Telmisartan, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone Added To Bupivacaine During Caudal Block
Status: UNKNOWN
Conditions: Caudal Block
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NobleStitch EL STITCH Trial is a PFO Comparative Trial
Status: SUSPENDED
Conditions: Foramen Ovale, Patent|Stroke, Ischemic
Interventions: DEVICE: NobleStitch™EL Suture Mediated Closure System|DEVICE: Amplatzer PFO Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine, Nab-paclitaxel, and Ficlatuzumab (AV-299) in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Ficlatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: DRUG: 4 degree chilled saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet Management on Hepatic Encephalopathy of Patients With Variceal Bleeding After Intrahepatic Portosystemic Shunt Creation
Status: UNKNOWN
Conditions: Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: diet management strategy for encephalopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL)
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Interpersonal psychotherapy for major depression following perinatal loss|BEHAVIORAL: Coping with Depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Study of Timolol Eye Drops and Paroxetine Capsules
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine|DRUG: Placebo|DRUG: timolol maleate|DRUG: timolol maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PAD Followed by Autologous Stem Cell Transplantation (ASCT) to Treat Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: PAD Followed by ASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Adding Chemotherapy to Radiotherapy for Treating Bladder Cancer.
Status: COMPLETED
Conditions: Transitional Cell Carcinoma of Urinary Bladder
Interventions: DRUG: Cisplatin|RADIATION: External beam radiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Direct Current Stimulation on Decision Making and Cognitive Flexibility in Gambling Disorder
Status: COMPLETED
Conditions: Gambling Disorder
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of I 0401 in the Treatment of Tibial Plateau Fractures Requiring Grafting
Status: COMPLETED
Conditions: Tibia Plateau Fractures
Interventions: DRUG: I-0401 (a new bone graft substitute)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating Exercise Habits Through Incentives for Routines
Status: COMPLETED
Conditions: Body Weight
Interventions: BEHAVIORAL: Workout Window Reminders|BEHAVIORAL: Individual Workout Incentive Payment|BEHAVIORAL: Lump Incentive Payments|BEHAVIORAL: Partner Assignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Docetaxel, Estramustine and Short Term Androgen Withdrawal for Patients With a Rising PSA After Local Treatment
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Estramustine|DRUG: Casodex|DRUG: Zoladex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics, And Effects On Histamine-Induced Wheal Of PF-05180999 In Healthy Adults
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: PF-05180999|DRUG: Placebo|DRUG: 120 mg MR PF-05180999|DRUG: 360 mg MR PF-05180999|DRUG: 10 mg cetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy?
Status: COMPLETED
Conditions: Cerebral Palsy|Muscle Spasticity
Interventions: DRUG: botox|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningeal Metastases
Status: COMPLETED
Conditions: Meningeal Carcinomatosis
Interventions: PROCEDURE: lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Effects of Parathyroid Hormone (PTH) on the Proximal Femur
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Teriparatide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Letrozole in Assisted Reproductive Technology
Status: UNKNOWN
Conditions: to Evaluate Letrozole as a Modality for Minimal Ovarian Stimulation in ICSI Cycles .
Interventions: DRUG: Letrezole plus FSH|DRUG: Standard protocol for induction of ovulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Overground Bodyweight Supporting Walking System Andago
Status: COMPLETED
Conditions: Gait Disorders, Neurologic|Cerebral Palsy|Stroke|Traumatic Brain Injury|Child, Only|Gait Disorders in Children
Interventions: DEVICE: Andago|OTHER: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Dexamethasone for Pain Flare After Radiotherapy of Painful Bone metastasesZonMW 11510009
Status: COMPLETED
Conditions: Bone Metastases
Interventions: DRUG: Dexamethasone acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic Prophylaxis in Ragged Placental Membranes
Status: COMPLETED
Conditions: Endometritis Postpartum|Endometritis|Membranes; Retained
Interventions: DRUG: Prophylactic antibiotics|OTHER: No prophylaxis (Amox-clav withheld)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy
Status: UNKNOWN
Conditions: Diabetic Non-proliferative Retinopathy|Type2 Diabetes
Interventions: DRUG: Tangwang prescription|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Single IV Administration of P2G12
Status: UNKNOWN
Conditions: HIV Infection
Interventions: DRUG: P2G12 Dose Cohort 1|DRUG: P2G12 Dose Cohort 2|DRUG: P2G12 Dose Cohort 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Can High Convection Volumes be Achieved in Each Patient During Online Post-dilution Hemodiafiltration?
Status: COMPLETED
Conditions: End-stage Renal Disease|Renal Replacement Therapy|Hemodiafiltration|Convection Volume
Interventions: OTHER: Optimization of HDF key parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.
Status: RECRUITING
Conditions: Advanced Breast Cancer|Female Breast Cancer
Interventions: DRUG: FCN-437c, Letrozole or anastrozole, Goserelin acetate|DRUG: Placebo, Letrozole or anastrozole, Goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Bariatric surgery involving Roux-en-Y gastric bypass|PROCEDURE: Bariatric surgery involving Laparoscopic adjustable gastric banding|PROCEDURE: Bariatric surgery involving Laparoscopic sleeve gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: hypoglycemic Agents(metformin)|DRUG: lipid-lowering drug(Statin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Readmissions at IBD Centres of Excellence
Status: UNKNOWN
Conditions: Colitis, Ulcerative|Crohn Disease|Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Nurse Follow-Up|OTHER: Electronic Monitoring|OTHER: Post-Discharge Questionnaire|OTHER: Post-Discharge Questionnaire|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment
Status: RECRUITING
Conditions: Carcinoma|Non-Small-Cell Lung
Interventions: DRUG: Savolitinib|DRUG: Osimertinib|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Benzonatate on QT Intervals Following Single Dose Administration of Benzonatate to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Benzonatate 200 mg|DRUG: Benzonatate 800 mg|DRUG: Moxifloxacin 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
Status: COMPLETED
Conditions: Infant Development|Sensory Disorder|Sensory Processing Disorder|Motor Delay|Infant, Premature, Diseases|Infant, Very Low Birth Weight|Infant Asphyxia|Development Delay
Interventions: OTHER: Measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Evaluation of Intracranial Hypertension by Ultrasound Measurement of Variations in the Diameter of the Sheath of the Optic Nerve in the Excision of a Tumor or Biopsy Supratentorial Brain
Status: COMPLETED
Conditions: Supratentorial Brain Tumor
Interventions: PROCEDURE: ultrasound measurement of variations in the diameter of the sheath of the optic nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: The Effect of Dietary Intervention on Endothelial Glycocalyx in Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DIETARY_SUPPLEMENT: Food supplement Endocalyx|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bone Healing Accelerant (BHA) Versus Autologous Bone Grafting (ABG) for Hindfoot or Ankle Arthrodesis
Status: WITHDRAWN
Conditions: Foot Deformities
Interventions: COMBINATION_PRODUCT: BHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Interpersonal Psychotherapy for Depression and PTSD Among HIV+ Women in Kenya
Status: COMPLETED
Conditions: Depression|Posttraumatic Stress Disorder|HIV
Interventions: BEHAVIORAL: interpersonal psychotherapy|BEHAVIORAL: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Generalized Anxiety Disorder Adjunct Study
Status: COMPLETED
Conditions: Anxiety|Anxiety Disorders|Anxiety Neuroses|Anxiety States
Interventions: DRUG: Placebo|DRUG: quetiapine fumarate XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS-APO(a)Rx in Participants With High Lipoprotein(a)
Status: COMPLETED
Conditions: Elevated Lipoprotein(a)
Interventions: DRUG: ISIS-APO(a)Rx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: LBH589 (Panobinostat®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NicVAX/Placebo as an Aid for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation|Smoking|Tobacco Cessation
Interventions: BIOLOGICAL: NicVAX vaccine|BIOLOGICAL: Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Versus Home Introduction of Milk in Children With Non-IgE-mediated Cow's Milk Allergy
Status: RECRUITING
Conditions: Cow Milk Allergy|Food Allergy
Interventions: DIAGNOSTIC_TEST: Cow's milk|DIAGNOSTIC_TEST: Placebo|DIAGNOSTIC_TEST: Home introduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post Isometric Relaxation and Mulligan Bent Leg Raise on Hamstring Tightness in High School Students
Status: COMPLETED
Conditions: Hamstring Injury|Hamstring Tendon Injury
Interventions: OTHER: post isometric relaxation and muligan bent leg raise|OTHER: muligan bent leg raise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Prevention And Treatment On Obesity And Weight Management By Oral Supplementation Of Probiotics And Prebiotics
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Study product A (Wonderlab wonder4shape)|DIETARY_SUPPLEMENT: Study product B (Wonderlab wonder4shape)|DIETARY_SUPPLEMENT: Study product C (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Study of Jaktinib in Participants With Moderate to Severe Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate-to-Severe Plaque Psoriasis
Interventions: DRUG: Jaktinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clonidine - Ropivacaine in Peribulbar Anesthesia
Status: COMPLETED
Conditions: Indication for Surgery of the Posterior Segment Under Locoregional Anaesthesia
Interventions: DRUG: 5 ml Ropivacaine 10% + physiological saline|DRUG: 5 ml Ropivacaine 10% + Clonidine 1 µg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Dyslipidemias
Interventions: OTHER: Metformin|DRUG: SGLT2 inhibitor|DRUG: ezetimibe
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Zinc Oxide Underarm Formula on Normal and Injured Skin in Healthy Volunteers
Status: COMPLETED
Conditions: Microbiome of the Axillae
Interventions: OTHER: Formula with ZnO|OTHER: Formula without ZnO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Benefit of Peptide Based Diet in Obese HEN Patients
Status: ENROLLING_BY_INVITATION
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Peptamen Intense VHP, Nestlé Health Science, Switzerland
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alimta® Plus Cisplatin & Paclitaxel Given Intraperitonelly; First Line Tx Stage III Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel|DRUG: pemetrexed disodium|OTHER: biologic sample preservation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desflurane Versus Propofol in the Sitting Position
Status: COMPLETED
Conditions: Cerebral Ischemia
Interventions: DRUG: propofol|DRUG: Desflurane|DRUG: alfentanil|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Neuroscience Education and Therapeutic Exercise as a Treatment for Breast Cancer Survivors Living With Sequelae
Status: COMPLETED
Conditions: Breast Neoplasms|Pain, Chronic|Kinesiophobia|Breast Cancer
Interventions: OTHER: Pain neuroscience education and therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells to Treat Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Umbilical cord mesenchymal stem cells|BIOLOGICAL: Controlled suspension liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Perfusion, Coronary Flow Reserve and Kinetic Analysis During Dobutamine Stress Echocardiography
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Disease
Interventions: DIAGNOSTIC_TEST: Stress echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Soluble Epoxide Hydrolase (s-EH) Inhibitor in Patients With Mild to Moderate Hypertension and Impaired Glucose Tolerance
Status: COMPLETED
Conditions: Hypertension|Impaired Glucose Tolerance
Interventions: DRUG: AR9281|DRUG: AR9281|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of PD-1 Inhibitor Pembrolizumab in PD-1 Naive Cutaneous Squamous Cell Carcinoma (cSCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hypoglycaemia in Patients With Diabetes Mellitus Type 2 on Platelet Activation
Status: COMPLETED
Conditions: Diabetes Mellitus With Hypoglycemia|Diabetes Mellitus, Type 2|Hypoglycemia|Hypoglycemic Episode
Interventions: OTHER: Euglycaemic Clamp|OTHER: Hyperinsulinaemic/Hypoglycaemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum
Status: WITHDRAWN
Conditions: Rectal Cancer|Neoplasm Metastasis
Interventions: DRUG: Panitumumab with capecitabine and oxaliplatin (CAPOX) followed by|DRUG: Panitumumab with capecitabine and radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIFE-BTK Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Limb Ischemia (CLI)
Interventions: DEVICE: Esprit BTK Device|DEVICE: Percutaneous Transluminal Angioplasty (PTA) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Safety of a Measles Vaccine (Dry Powder) Administered by Two Different Devices
Status: COMPLETED
Conditions: Prophylaxis for the Measles Infection
Interventions: BIOLOGICAL: PMV via Puffhaler® device|BIOLOGICAL: PMV via SoloventTM device|BIOLOGICAL: Licensed Subcutaneous Measles Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans
Status: COMPLETED
Conditions: Human Microbiome
Interventions: DRUG: Intranasal Mupirocin and Topical Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of PX-866 and Docetaxel in Solid Tumors
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)|Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Interventions: DRUG: Docetaxel|DRUG: PX-866
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery and Pharmacokinetics of 14C TZP-101
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: TZP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Drug Interaction Study Between Amlodipine,Olmesartan and Rosuvastatin in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sevikar(amlodipne/olmesartan)|DRUG: crestor(Rosuvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients
Status: UNKNOWN
Conditions: Untreated Adult Acute Myeloid Leukemia|Effect of Drugs|Drug Safety
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Alfimeprase to Rapidly Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery on Leg Arteries
Status: COMPLETED
Conditions: Arterial Occlusive Diseases
Interventions: DRUG: alfimeprase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Blood Loss Under Standard Versus Low Pneumoperitoneum Pressure During Laparoscopic Liver Resection.
Status: RECRUITING
Conditions: Liver Tumor
Interventions: PROCEDURE: Pneumoperitoneum 14mmHg|PROCEDURE: Pneumoperitoneum 10mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.
Status: NOT_YET_RECRUITING
Conditions: Plaque|Gingivitis
Interventions: DRUG: Stannous fluoride toothpaste|DRUG: Colgate Cavity Protection Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of rhEGF in Diabetic Foot Ulcer Patients With Uncontrolled Diabetic Mellitus
Status: COMPLETED
Conditions: Diabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus
Interventions: DRUG: rhEGF(recombinant human Epidermal Growth Factor)|DRUG: placebo of rhEGF(recombinant human Epidermal Growth Factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Community Medical Center, Continuous Quality Improvement Project, Rapid Sequence Intubation
Status: RECRUITING
Conditions: Intubation, Intratracheal|Rapid Sequence Induction and Intubation|Checklist
Interventions: OTHER: Intubation Checklist|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Dialogue-based Online Intervention Against Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: BEHAVIORAL: ceprica (additional to treatment as usual)|BEHAVIORAL: active control intervention (additional to treatment as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Single-Arm Clinical Trial to Evaluate The Efficacy of Abatacept in Moderate to Severe Patch Type Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Capacitive Radiofrequency at the Dermis and Adipose Tissue
Status: COMPLETED
Conditions: Adiposity|Abdominal Obesity
Interventions: DEVICE: Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas
Status: COMPLETED
Conditions: AIDS-Related Plasmablastic Lymphoma|AIDS-Related Primary Effusion Lymphoma|Ann Arbor Stage I Diffuse Large B-Cell Lymphoma|Ann Arbor Stage I Grade 3 Follicular Lymphoma|Ann Arbor Stage II Diffuse Large B-Cell Lymphoma|Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 3 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage III Diffuse Large B-Cell Lymphoma|Ann Arbor Stage III Grade 3 Follicular Lymphoma|Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma|Ann Arbor Stage IV Grade 3 Follicular Lymphoma|HIV Infection|Plasmablastic Lymphoma|Primary Effusion Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Grade 3 Follicular Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Cylex® ImmuKnow® Assay
Status: COMPLETED
Conditions: Leukemia|Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia|Hodgkin's Disease|Multiple Myeloma|Myelodysplastic Syndromes|Myeloproliferative Disorders|Aplastic Anemia|Chronic Myelogenous Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKAYCE™) - Extension Phase
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Arikayce™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamic Activity of JNJ-26528398 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: JNJ-26528398|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04629991 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04629991|DRUG: PF-04629991|DRUG: PF-04629991
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Trial Comparing Two Two Sequences of Therapy in Colorectal Metastatic Patients
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOX-4|DRUG: Irinotecan/Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Acute-graft-versus-host Disease|Chronic Graft-versus-host-disease|Solid Organ Transplant
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety and Efficacy of DE-117 in Subjects With POAG or OH Who Are Non-/Low-responders to Latanoprost: FUJI Study
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma or Ocular Hypertension
Interventions: DRUG: DE-117 ophthalmic solution|DRUG: Latanoprost ophthalmic solution 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Pharmacodynamic Study of MabThera (Rituximab) Plus Methotrexate in Patients With Rheumatoid Arthritis (RA)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children With CAH
Status: RECRUITING
Conditions: Congenital Adrenal Hyperplasia|21-OHD
Interventions: DRUG: Tildacerfont
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
Status: COMPLETED
Conditions: Muscle Wasting|Protein Intake|Ketosis|Caloric Restriction
Interventions: DRUG: Ketone supplementation|DIETARY_SUPPLEMENT: Increased protein intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RDEA806 in Hyperuricemic Subjects With Symptomatic Gout
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: RDEA806|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety of MN-221 in Subjects With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: MN-221 (Dose Group 1)|DRUG: MN-221 (Dose Group 2)|DRUG: MN-221 (Dose Group 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Phenytoin Mucoadhesive Paste on Wound Healing After Oral Biopsy
Status: UNKNOWN
Conditions: Wound Healing|Pain
Interventions: DRUG: Phenytoin paste|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of AZD7503 in Japanese Healthy Participants.
Status: COMPLETED
Conditions: Heathy Participants
Interventions: DRUG: AZD7053|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Predictors in Colorectal IBD Surgery Recovery
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: Questionnaires administration|OTHER: Langer Mindfulness Scale (LMS)|OTHER: Mindful Attention Awareness Scale (MAAS)|OTHER: Cognitive Flexibility Scale (CFS)|OTHER: Life Orientation Test (LOT)|OTHER: Mini Locus of Control test (MLS)|OTHER: Hospital Anxiety and Depression Scale (HADS)|OTHER: Perceived Stress Scale (PSS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phenelzine Sulfate and Docetaxel in Treating Patients With Prostate Cancer With Progressive Disease After First-Line Therapy With Docetaxel
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Prostatic Adenocarcinoma|Prostate Adenocarcinoma|Recurrent Prostate Carcinoma
Interventions: PROCEDURE: Biopsy of Prostate|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Phenelzine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connective Tissue Massage And Classical Massage In Patients With Chronic Non-Specific Low Back Pain.
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Connective Tissue Massage|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)|OTHER: Classical Massage|DEVICE: Therapatic Ultrasound|OTHER: Heat Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Need for the Pseudophakic Intraoperative Abberrometry in Toric IOL Implantation
Status: COMPLETED
Conditions: Cataract|Nuclear Sclerosis|Cortical Cataract|Posterior Subcapsular Cataract|Astigmatism
Interventions: DIAGNOSTIC_TEST: Pseudophakic Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard vs. Accelerated Corneal Crosslinking
Status: RECRUITING
Conditions: Keratoconus|Ectasia Corneal
Interventions: COMBINATION_PRODUCT: riboflavin 0.1%|COMBINATION_PRODUCT: Riboflavin 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin, and Dimethylxanthenone Acetic Acid in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: vadimezan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tart Cherry (Prunus Cerasus) Concentrate on Physiological and Cognitive Function
Status: COMPLETED
Conditions: Cardiometabolic Risk Factors|Cognitive Function|Exercise Capacity
Interventions: DIETARY_SUPPLEMENT: Montmorency tart cherry concentrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Approval Study of the TECNIS® Toric Extended Cylinder Range Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Cataract|Astigmatism
Interventions: DEVICE: TECNIS Toric Models ZCT450, ZCT525 or ZCT600
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Use of i/t Curve in Assessment of Phototherapy Effects
Status: COMPLETED
Conditions: Nerve Disorders
Interventions: RADIATION: Irradiations of the biceps brachii muscle with PILER light. The participants were randomized into 4 groups: group v - no filter/ group x - red filter/ group y - blue filter/ group z - placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Timed-Restricted Eating on Metabolic Health
Status: RECRUITING
Conditions: Obesity|Non-Alcoholic Fatty Liver Disease|Insulin Resistance
Interventions: BEHAVIORAL: Early time restricted eating|BEHAVIORAL: Late time restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Sudden Death
Interventions: DEVICE: Implantable Cardioverter Defibrillator + Usual Care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a 4 Stage Bowel Obstruction Cancer Diet
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Carcinoma|Colorectal Adenocarcinoma|Colorectal Cancer Metastatic|Ovarian Cancer|Ovarian Neoplasm|Metastatic Colorectal Cancer|Metastatic Ovary Cancer|Peritoneal Carcinomatosis|Bowel Obstruction
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus, Bendamustine and Rituximab for Relapsed Follicular Lymphoma or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Temsirolimus, Rituximab, Bendamustin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Venezuelan Equine Encephalomyelitis (VEE) Vaccine as Booster Vaccine in Adults
Status: NOT_YET_RECRUITING
Conditions: Venezuelan Equine Encephalomyelitis
Interventions: BIOLOGICAL: 0.5 mL Inactivated, Dried, C-84, TSI-GSD 205, Lot 7, Run 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: PC14586|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enbrel-Sulfasalazin-Early-Axial Spondyloarthritis (AS)
Status: UNKNOWN
Conditions: Moderate to Severe Active Axial Spondyloarthritis
Interventions: DRUG: Etanercept 25mg|DRUG: Sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Frontotemporal Lobar Degeneration|Memory Disorders
Interventions: DEVICE: Nautilus NeuroWaveTM System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of FOLFIRI Plus OMP-21M18 as 1st or 2nd-line Treatment in Subjects With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: OMP-21M18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Medial Wedge on Static Balance in Pronated Feet
Status: COMPLETED
Conditions: Foot; Deformity, Valgus, Congenital|Foot; Deformity, Valgus (Acquired)|Foot Deformities|Flatfoot
Interventions: OTHER: Medial calcaneal wedge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Corrective External Support and Regional Vibration Applications in Subacromial Pain Syndrome
Status: RECRUITING
Conditions: Subacromial Pain Syndrome
Interventions: OTHER: Standard Physiotherapy Program|OTHER: Kinesio Taping|OTHER: Local Vibration Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Capecitabine|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Effectiveness of Cortical Stimulation in Subjects With Major Depressive Disorder
Status: TERMINATED
Conditions: Depression|Depressive Disorder
Interventions: DEVICE: Cortical Stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dorsal Root Ganglion Thermal Radiofrequency Versus Pulsed Radiofrequency for Metastatic Pain in Thoracic Vertebral Body
Status: COMPLETED
Conditions: Bone Neoplasm,Malignant Vertebral Column Thoracic Secondary
Interventions: DEVICE: PRF on DRG|DEVICE: TRF on DRG|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of MI Paste Plus and Remin Pro on Remineralization of Post-Orthodontic White Spot Lesions
Status: COMPLETED
Conditions: White Spot Lesion|Remineralization
Interventions: COMBINATION_PRODUCT: MI Paste Plus|COMBINATION_PRODUCT: Remin Pro|COMBINATION_PRODUCT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter in the Prevention of Urinary Tract Infections and Crystallization Study(CPUTICS)
Status: NOT_YET_RECRUITING
Conditions: Urinary Catheter
Interventions: OTHER: Types of catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of the Role of MRI in the Perioperative Management of Pancreas Adenocarcinomas
Status: COMPLETED
Conditions: Pancreas Adenocarcinomas
Interventions: OTHER: Pre- and postoperative MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Criteria for Accessory Vein Obliteration Trial.
Status: UNKNOWN
Conditions: Arteriovenous Fistula Maturation Failure
Interventions: PROCEDURE: HAQ criteria|PROCEDURE: Current Recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Body Radiotherapy (SABR) for Oligometastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Tumors
Interventions: RADIATION: Stereotactic Ablative Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT