pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prevention of Hypocalcemia in Patients Undergoing Total Thyroidectomy Plus Central Neck Dissection
Status: COMPLETED
Conditions: Hypocalcemia
Interventions: DIETARY_SUPPLEMENT: Oral calcium plus vitamin D|DIETARY_SUPPLEMENT: Oral calcium alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Is Omega-3 Fatty Acid Red Blood Cell (RBC) Saturation Product Dependent?
Status: COMPLETED
Conditions: Cardioprotective Levels
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare PK, PD and Safety of UI058 and UIC202004 in Healthy Subjects
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: administration of UI058|DRUG: administration of UIC202004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium|GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: biopsy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Reliability and Validity of the L-test in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: L test|OTHER: Timed Up and Go test|OTHER: 10 meter walk test|OTHER: Six Minute Walk Test|OTHER: The timed 360° turn test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of TetraSOD® Efficacy to Improve Semen Parameters in Men With Idiopathic Infertility
Status: UNKNOWN
Conditions: Infertility, Male
Interventions: DIETARY_SUPPLEMENT: Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activity|DIETARY_SUPPLEMENT: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Paliperidone Palmitate and RISPERDAL CONSTA in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: RISPERDAL CONSTA|DRUG: Paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Community Mobile Outreach Approach Compared to Facility Based Directly Observed Treatment Short Course on Treatment Outcome Among Tuberculosis Patients in Jeddah: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Tuberculosis
Interventions: PROCEDURE: Mobile Outreach Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Outcomes Related to Treatment of Distal Symmetric Polyneuropathy Using Semiconductor Embedded Therapeutic Socks
Status: NOT_YET_RECRUITING
Conditions: Diabetic Neuropathy
Interventions: DEVICE: Semiconductor Embedded Therapeutic Socks|DEVICE: Placebo Socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours
Status: RECRUITING
Conditions: Solid Tumours
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Ribose in Patients Diagnosed With Fibromyalgia
Status: SUSPENDED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: D-ribose|OTHER: dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency
Status: NOT_YET_RECRUITING
Conditions: Anemia|Decreased Glomerular Filtration Rate
Interventions: OTHER: consultation with a specialist|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sleep Disordered Breathing and Chronic Pain
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: servo ventilation auto|DEVICE: Continuous positive airway pressure|DEVICE: servo ventilation manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internal Mammary Sentinel Lymph Node Biopsy in Early Breast Cancer Patients With Clinically Axillary Node -Positive
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: IM-SLNB|RADIATION: 99mTc-SC|DEVICE: Histologic Examination|DEVICE: LSG|DRUG: Methylthioninium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study to Compare Two Injection Devices for BMN 111 in Healthy Participants
Status: TERMINATED
Conditions: Achondroplasia
Interventions: COMBINATION_PRODUCT: BMN 111 administration via Injector Pen|DRUG: BMN 111 administration via vial and syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Preparation of Abortions Under Paracervical Block in the First Trimester:
Status: COMPLETED
Conditions: Surgical Abortion
Interventions: DRUG: Mifépristone versus Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic, Dietary and Environmental Influences on Vitamin D Metabolism
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 800 IU Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Suubi4StrongerFamilies
Status: ACTIVE_NOT_RECRUITING
Conditions: Child Behavioral Health
Interventions: BEHAVIORAL: Economic Empowerment (EE)|BEHAVIORAL: Multiple Family Group based Family Strengthening (MFG-based FS)|BEHAVIORAL: EE plus MFG-based FS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's Disease
Status: UNKNOWN
Conditions: Dupuytren Contracture|Dupuytren's Disease of Finger
Interventions: PROCEDURE: Percutaneous Needle Aponeurotomy|DRUG: XIAFLEX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Plasma Lipids on β Cell Function and Insulin Sensitivity
Status: COMPLETED
Conditions: Hypertriglyceridemia|Glucose Intolerance
Interventions: OTHER: 20% Intralipid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction
Status: COMPLETED
Conditions: Cocaine Dependence|Cocaine Addiction
Interventions: DRUG: Metyrapone|DRUG: Oxazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D to Improve Outcomes by Leveraging Early Treatment
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Vitamin D Deficiency|Critical Illness
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Suvorexant for Insomnia in Parkinson Disease
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Inflammation and Neuronal Integrity Markers in Patients With First-episode Conversive Motor Disorder
Status: COMPLETED
Conditions: Conversion Disorder
Interventions: DIAGNOSTIC_TEST: blood inflammatory markers (TNF-α, IL1ra, RsIL-2, IL-6, IL-10, IL-18, IFNγ, MCP-1/CCL2 GFAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Experience of Upper Limb Prosthesis Use
Status: UNKNOWN
Conditions: Prosthesis User|Amputation|Upper Limb Amputation at the Wrist|Upper Limb Amputation Above Elbow (Injury)|Upper Limb Amputation Below Elbow (Injury)
Interventions: OTHER: Qualitative Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis|Diabetes Mellitus
Interventions: DRUG: 5% dextrose in water|DRUG: TZP-101|DRUG: TZP-101|DRUG: TZP-101|DRUG: TZP-101|DRUG: TZP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies
Status: WITHDRAWN
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Blastic Phase Chronic Myelogenous Leukemia|Cutaneous B-cell Non-Hodgkin Lymphoma|de Novo Myelodysplastic Syndromes|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Post-transplant Lymphoproliferative Disorder|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Refractory Multiple Myeloma|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|PROCEDURE: double-unit umbilical cord blood transplantation|RADIATION: total-body irradiation|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sublingual Immunotherapy on Grasspollen Allergy
Status: COMPLETED
Conditions: Hayfever
Interventions: DRUG: Oralgen|PROCEDURE: Nasal biopsy|PROCEDURE: Nasal washing|PROCEDURE: Peak nasal inspiratory flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Plantar Heel Pain: Multisegment Foot Motion and Muscle Function, FFI Translation, and Evaluation of Treatments (Subproject1) Effectiveness of Strengthening Exercise Program on Symptoms in Patients With PHP (Subproject3)
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: PROCEDURE: Conservative physical therapy treatment with strengthening exercise program, and Conservative physical therapy treatment with stretching exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CellCept (Mycophenolate Mofetil) Combined With Calcineurin Inhibitors in Liver Transplant Patients.
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Mycophenolate mofetil|DRUG: CNI (50%)|DRUG: CNI (≥75%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Status: COMPLETED
Conditions: Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
Interventions: DRUG: diclofenac|DRUG: Norco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0125, Chemotherapy, Total-Body Irradiation, and Peripheral Stem Cell Transplantation in Treating Older Patients With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclosporine|DRUG: fludarabine|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation
Status: RECRUITING
Conditions: Gout|Chronic Kidney Disease|Renal Transplantation
Interventions: DRUG: Anakinra 100Mg/0.67Ml Inj Syringe|DRUG: Prednisone|DRUG: Placebo of Prednisone|DRUG: Placebo of Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability, and Distribution and Activity in the Body of NNC0148-0000-0287 Injected Under the Skin in Healthy Subjects and in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Healthy
Interventions: DRUG: 148-0287-A-4.2mM-cartridge|DRUG: placebo|DRUG: 148-0287-A-4.2mM-cartridge|DRUG: placebo|DRUG: insulin glargine|DRUG: sodium chloride 0.9% w/v
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-PRF Versus A-PRF on Palatal Wound Healing
Status: COMPLETED
Conditions: Palate; Wound
Interventions: PROCEDURE: L_PRF|PROCEDURE: A-PRF|PROCEDURE: Palatal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Spine Manipulation on Pressure Pain Sensitivity of Active Myofascial Trigger Points in Rhomboid Muscle
Status: COMPLETED
Conditions: Trigger Points
Interventions: OTHER: Thoracic manipulation|OTHER: conventional pt protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inhaled Bicarbonate on Airway pH in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: hypertonic bicarbonate|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy in Relief of Dyspnea by HVNI: Evaluation of New Device Equivalence
Status: TERMINATED
Conditions: Dyspnea|Hypercapnia|Respiratory Insufficiency
Interventions: DEVICE: Conventional Precision Flow|DEVICE: HVNI HVT2.0 Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Thalidomide in Children With Transfusion Dependent Thalassemia
Status: COMPLETED
Conditions: Transfusion-dependent Thalassemia
Interventions: DRUG: Thalidomide Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency Department
Status: COMPLETED
Conditions: Gastritis|Peptic Ulcer|Peptic Ulcer Perforation|Stomach Ulcer
Interventions: OTHER: Urea Breath Test (UBT) for H. pylori infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder Instability
Status: RECRUITING
Conditions: Instability, Joint|Shoulder Dislocation|Shoulder Injuries|Shoulder Subluxation|Anterior Shoulder Instability|Glenoid; Dislocation
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Transfusion Strategies in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Congenital Heart Disease|Cardiac Surgery|Blood Transfusion|Morbidity, Multiple
Interventions: PROCEDURE: Cardiac surgery in grown-up congenital heart disease patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dutch Sub Study: Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA). PET Sub Study
Status: COMPLETED
Conditions: Rosuvastatin|Heart Failure|Positron Emission Tomography (PET)
Interventions: DRUG: Rosuvastatin|PROCEDURE: Positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)
Status: RECRUITING
Conditions: Node-positive Breast Cancer
Interventions: PROCEDURE: Tailored axillary surgery - both Arms|RADIATION: Radiotherapy - Arm A|RADIATION: Radiotherapy - Arm B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Safety and Tolerability Study of TML-6 in Healthy and Elderly Volunteers for Alzheimer's Disease Treatment
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: TML-6 Granules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding the Immune Response to Two Different Meningitis Vaccines
Status: COMPLETED
Conditions: Meningitis|Meningococcal Disease|Septicaemia
Interventions: BIOLOGICAL: MenACWY-CRM conjugate vaccine (Menveo, Novartis)|BIOLOGICAL: MenACWY-PS polysaccharide vaccine, ( ACWYVax, GSK) and MenACWY-CRM conjugate vaccine (Menveo, Novartis)|BIOLOGICAL: MenACWY-PS polysaccharide vaccine, ( ACWYVax, GSK) and MenACWY-CRM conjugate vaccine (Menveo, Novartis)|BIOLOGICAL: 1/5th dose MenACWY-PS polysaccharide vaccine, ( ACWYVax, GSK) and MenACWY-CRM conjugate vaccine (Menveo, Novartis)|BIOLOGICAL: Polysaccharide (subcutaneously)-conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Dasatinib|BIOLOGICAL: Relatlimab|BIOLOGICAL: Ipilimumab|DRUG: BMS-986205
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib in Hospitalized Patients With COVID-19 Pneumonia
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Tofacitinib 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Trial of LBL-007 Combined With Tislelizumab in the Treatment of Malignant Tumors
Status: RECRUITING
Conditions: Malignant Tumors
Interventions: DRUG: LBL-007 Injection|DRUG: Tislelizumab Injection|DRUG: Cisplatin Injection|DRUG: Gemcitabine Hydrochloride for Injection|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Exclusion of Abdominal Aortic Aneurysms in High Risk Patients
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm|Iliac Aneurysm|Internal Iliac Aneurysm
Interventions: DEVICE: Endovascular Aneurysm Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Carvedilol Tablets USP 12.5 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting State
Interventions: DRUG: Carvedilol Tablets USP 12.5 mg|DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetic Nephropathy|Essential Hypertension
Interventions: DRUG: spironolacone 25 mg tablets added to losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability of Zinc-fortified Lipid-based Nutrient Supplements
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: LNS with zinc|DIETARY_SUPPLEMENT: LNS without zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Radiation Therapy and Transarterial Chemoembolization (TACE) to Treat Hepatocellular Carcinoma (HCC)
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Radiation therapy|OTHER: Transarterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Repletion and Maintenance in IBD: How Much and How Often
Status: WITHDRAWN
Conditions: Inflammatory Bowel Diseases|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D (ergocalciferol and/ or cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiographic Evaluation of Bone Height Gain With Dental Implant Placed Simultaneously With Closed Sinus Lifting Using Hydraulic Lift Technique Versus Summers' Osteotome Technique in Posterior Edentulous Maxilla (RCT)
Status: UNKNOWN
Conditions: Evaluations, Diagnostic Self
Interventions: PROCEDURE: Using of hydraulic lifter device for closed sinus lifting|BEHAVIORAL: patient satisfaction evaluation after using hydraulic lifter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IMR-687 in Subjects With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: IMR-687|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Endometrial Carcinoma|Female Reproductive System Disorder|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Stage I Uterine Corpus Cancer AJCC v8|Stage IA Cervical Cancer AJCC v8|Stage IA Ovarian Cancer AJCC v8|Stage IA Uterine Corpus Cancer AJCC v8|Stage IA1 Cervical Cancer AJCC v8|Stage IA2 Cervical Cancer AJCC v8|Stage IB1 Cervical Cancer AJCC v8|Stage IC Ovarian Cancer AJCC v8
Interventions: BEHAVIORAL: Healthcare Activity|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doppler-guided or Non Doppler-guided Arterial Ligation and Mucopexy for Third Degree Hemorrhoids: That is the Question
Status: UNKNOWN
Conditions: Hemorrhoids Prolapse
Interventions: PROCEDURE: mucopexy with Doppler artery ligation|PROCEDURE: mucopexy without Doppler artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healing of the Esophageal Mucosa After RFA of Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: PROCEDURE: Baseline surveillance endoscopy|PROCEDURE: Radiofrequency ablation|PROCEDURE: Follow up endoscopy 1|PROCEDURE: Follow up endoscopy 2|PROCEDURE: Follow up endoscopy 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adolescent Anterior Knee Pain: ARP Wave Therapy vs. Physical Therapy
Status: UNKNOWN
Conditions: Knee Pain Chronic
Interventions: DEVICE: Accelerated Recovery Performance Wave Therapy|DIAGNOSTIC_TEST: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Patient Satisfaction Between 3 Types Dressing Shoes
Status: COMPLETED
Conditions: Patients Requiring Forefoot Surgery
Interventions: DEVICE: Darco shoe|DEVICE: Podalux shoe|DEVICE: Standard dressing shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia
Status: NOT_YET_RECRUITING
Conditions: Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 6
Interventions: PROCEDURE: Intravenous infusion|PROCEDURE: Intrathecal injection|BIOLOGICAL: umbilical cord mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise During the Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Fatigue|Allogeneic Stem Cell Transplantation
Interventions: OTHER: Supervised exercise|OTHER: Exercise Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
Status: UNKNOWN
Conditions: FAP-Familial Adenomatous Polyposis
Interventions: DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose
Status: RECRUITING
Conditions: Opioid Overdose|Opiate Overdose
Interventions: DRUG: Nalmefene Injection|DRUG: Naloxone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Urothelial Carcinoma|Urothelial Neoplasms
Interventions: BIOLOGICAL: Coformulated favezelimab/pembrolizumab|BIOLOGICAL: Coformulated vibostolimab/pembrolizumab|COMBINATION_PRODUCT: EV|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials
Status: COMPLETED
Conditions: Neurofibromatosis 1|Neurofibroma, Plexiform
Interventions: BEHAVIORAL: Medication Event Monitoring System (MEMS^TM)|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics Study of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: XOMA 052|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estimate of the Activity and the Forecast of the Lupus Disease of the Adult by a Transcriptomic Score (STUDY LU-PUCE)
Status: COMPLETED
Conditions: Lupus Disease
Interventions: BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare Plasma Levels of Levodopa, Carbidopa and Entacapone After TRIGEL or Duodopa Infusion in PD Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: TRIGEL|DRUG: Duodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of a 3D Foot Scanner for the Therapeutic Footwear Fitting
Status: COMPLETED
Conditions: Diabetic Foot|Orthopedic Disorder|Foot Ankle Injuries
Interventions: OTHER: 3D feet scan (smart-fitting by Podiapp - Podartis s.r.l Unipersonale-Crocceta del Montello (TV), Italy).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's Disease
Status: RECRUITING
Conditions: Idiopathic Parkinson's Disease
Interventions: BIOLOGICAL: hAESCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treg Modulation With CD28 and IL-6 Receptor Antagonists
Status: COMPLETED
Conditions: Living-Donor Kidney Transplant|Kidney Transplant Recipients
Interventions: BIOLOGICAL: lulizumab pegol|BIOLOGICAL: antithymocyte globulin (rabbit)|DRUG: methylprednisolone|BIOLOGICAL: tocilizumab|DRUG: Prednisone|DRUG: everolimus|BIOLOGICAL: belatacept|DRUG: mycophenolate mofetil|DRUG: mycophenolic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate 4-year Antibody Persistence and Booster Response Following MenABCWY Vaccination in Healthy Adolescents and Young Adults Who Previously Participated in Studies V102_02 (NCT01210885) and V102_02E1 (NCT01367158)
Status: COMPLETED
Conditions: Meningococcal Disease|Infections, Meningococcal
Interventions: BIOLOGICAL: MenABCWY+OMV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults
Status: COMPLETED
Conditions: Hookworm Infection|Hookworm Disease
Interventions: BIOLOGICAL: Na-GST-1|BIOLOGICAL: CPG 10104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Infection Prophylaxis in Total Joint Replacement
Status: RECRUITING
Conditions: Periprosthetic Joint Infection
Interventions: DRUG: Chlorhexidine Gluconate|DRUG: Vancomycin Hydrochloride|OTHER: Povidone-Iodine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Simpler and Safer Deep Brain Stimulation for Parkinson's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson's Disease
Interventions: DEVICE: Bioinduction "Picostim" Deep Brain Stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Different General Anesthesia Regimes on Postoperative Sleep Quality
Status: RECRUITING
Conditions: Anesthesia|Surgery|Sleep Disorders
Interventions: PROCEDURE: maintenance with desflurane|PROCEDURE: maintenance with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study for Peripheral Neuromuscular Electrical Stimulation of the Quadriceps Muscle
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Brain Injuries|Muscle Atrophy
Interventions: DEVICE: Experimental FES cycling|DEVICE: Comparator FES cycling|OTHER: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Red and Infrared Lasers on Histopathology Collagen Formation in Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot|Wound Heal|Collagen Diseases
Interventions: DEVICE: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arimidex/Faslodex/Iressa Study: A Trial Using Arimidex, Faslodex and Iressa in Women With Breast Cancer
Status: TERMINATED
Conditions: BREAST CANCER
Interventions: DRUG: Iressa Day 1 given with Arimidex and Faslodex|DRUG: Iressa Day 21 given with Arimidex and Faslodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Nellix® EndoVascular Aneurysm Sealing System for the Treatment of Infrarenal Abdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: DEVICE: The Nellix® EndoVascular Aneurysm Sealing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Endoscopic Sinus Surgery|Nasal Polyps
Interventions: DRUG: Oxymetazoline|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antigen-specific Cancer Immunotherapy (TG01) and Gemcitabine as Adjuvant Therapy in Resected Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer, Resected
Interventions: BIOLOGICAL: TG01|BIOLOGICAL: TG01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retention, Stability and Performance Assessment of Denture Fixatives Versus no Fixative Control
Status: COMPLETED
Conditions: Dentures
Interventions: DEVICE: Paraffin based Denture Fixative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells for the Treatment of Non-union Fractures of Long Bones
Status: COMPLETED
Conditions: Atrophic Nonunion of Fracture
Interventions: DRUG: XCEL-MT-OSTEO-ALPHA|OTHER: autologous iliac crest|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Processes Study in Obese Women With and Without Eating Disorders
Status: COMPLETED
Conditions: Hyperalimentation and Obesity
Interventions: PROCEDURE: electroencephalography|BIOLOGICAL: Blood sampling|BEHAVIORAL: Questionnaires regarding eating habits (TFEQ, EDI) and anxiety/depression (HAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Efficacy of Intravenous Paracetamol and Dexketoprofen for Acute Nontraumatic Musculoskeletal Pain
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Real World Analysis Of Sutent In Patients With Metastatic Renal Cell Carcinoma In Community And Academic Centers To Assess The Impact Of Dose Variation On Duration Of Response And Overall Survival
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: OTHER: Sutent: Observational Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Audio and Video Brochures for Increasing Colorectal Cancer Screening Among Adults Living in Appalachia
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: OTHER: Best Practice|OTHER: Fecal Immunochemical Test|BEHAVIORAL: Health Education|BEHAVIORAL: Health Education|OTHER: Scheduled Notification|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effectiveness and Safety of TMF in the Treatment of Chronic Hepatitis B Patients With Normal ALT.
Status: ACTIVE_NOT_RECRUITING
Conditions: HBV Infection|Chronic Hepatitis b
Interventions: DRUG: Tenofovir Amibufenamide（TMF）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis|Seasonal Allergies
Interventions: DRUG: NS2 Ophthalmic Drops (0.5%)|DRUG: NS2 Ophthalmic Drops Vehicle (0.0%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lingual Tonsil Hypertrophy Grading and Its Relation to Sociodemographic Factors and Clinical Symptoms
Status: COMPLETED
Conditions: Lingual Tonsil Hypertrophy|Dysphagia
Interventions: DEVICE: Videolaryngoscopy|OTHER: Reflux Symptom Index Questionnaire|OTHER: Dysphagia Screening Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of Oral Administration of PTL101 (Cannabidiol) as an Adjunctive Treatment for Pediatric Intractable Epilepsy
Status: COMPLETED
Conditions: Epilepsy Intractable
Interventions: DRUG: PLT101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Fermented Plant-based Products High in Protein on Gut Microbiota and Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Interventions: OTHER: Fermented oat-based product|OTHER: Unfermented oat-based product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Ginseng on Cancer-Related Fatigue
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancers|Solid Tumors
Interventions: DRUG: Panax Ginseng|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: acetaminophen|DRUG: ibuprofen|DRUG: piroxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clomiphene in Males With Prolactinomas and Persistent Hypogonadism
Status: COMPLETED
Conditions: Hypogonadotropic Hypogonadism|Prolactinoma
Interventions: DRUG: Clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Remote Home Monitoring Acute Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis|Telemedicine|Healthdot|Patient Discharge|Monitoring
Interventions: OTHER: Early discharge with remote home monitoring.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Nerve Block
Interventions: PROCEDURE: Adductor Canal Block, Bupivacaine|PROCEDURE: Femoral Nerve Block, Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TachoSil Versus Standard Surgical Treatment for Air Leakage in Pulmonary Lobectomy (TC-021-IM)
Status: COMPLETED
Conditions: Pulmonary Diseases|Intraoperative Complications
Interventions: DRUG: Fibrinogen (human) + thrombin (human) (TachoSil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine
Status: COMPLETED
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: OTHER: Sham chiropractic manipulative therapy|OTHER: Chiropractic spinal manipulative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: FX005|DRUG: Placebo 1 (Carrier)|DRUG: Placebo 2 (Diluent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia
Status: NOT_YET_RECRUITING
Conditions: Prostatic Hyperplasia, Benign|Erectile Dysfunction
Interventions: DRUG: DTT106|DRUG: Dutasteride-Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Mini-Dose Glucagon (G-Pen Mini) in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: G-Pen Mini™ (glucagon injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic Acid
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Clavulanic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT