pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: tideglusib|DRUG: tideglusib|DRUG: tideglusib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain in Fibrous Dysplasia
Status: ENROLLING_BY_INVITATION
Conditions: Fibrous Dysplasia/McCune-Albright Syndrome
Interventions: DIAGNOSTIC_TEST: MRI-based Neuroimaging|DIAGNOSTIC_TEST: Non-contrast MRI|DIAGNOSTIC_TEST: 18F-FDG-PET/CT|DIAGNOSTIC_TEST: 18F-NaF-PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supportive Therapy in Androgen Deprivation Clinic in Improving Health Outcomes and Managing Side Effects in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Adenocarcinoma
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|OTHER: Counseling|OTHER: Educational Intervention|BEHAVIORAL: Exercise Intervention|DRUG: Goserelin Acetate|OTHER: Laboratory Biomarker Analysis|DRUG: Leuprolide Acetate|OTHER: Quality-of-Life Assessment|DRUG: Triptorelin Pamoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-exposure Prophylaxis (PrEP) Rapid Access
Status: COMPLETED
Conditions: Drug Use|Pre-exposure Prophylaxis (PrEP)|Opioid Use Disorder
Interventions: OTHER: PrEP Rapid Access|OTHER: HIV self-testing|OTHER: Dried blood spot testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Ombitasvir/Paritaprevir/Ritonavir in Japanese Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection With End Stage Renal Disease (ESRD) on Hemodialysis (HD)
Status: WITHDRAWN
Conditions: Chronic Hepatitis C Virus
Interventions: DRUG: Ombitasvir/paritaprevir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kuwa Free! - Live Free!
Status: RECRUITING
Conditions: HIV Infections|Contraception|Drug-drug Interaction
Interventions: DRUG: Cabotegravir/ Rilpivirine|DRUG: Etonogestrel (ETG) implant|DRUG: Intramuscular depo-medroxyprogesterone acetate (IM DMPA)|DRUG: Levonorgestrel|DRUG: NNRTI, PI, or INSTI-containing 1st or 2nd line ART regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Autologous Plasma Rich in Platelets and Extracellular Vesicles in the Surgical Treatment of Chronic Middle Ear Infections
Status: UNKNOWN
Conditions: Otitis Media Chronic|Tympanic Membrane Perforation
Interventions: DRUG: Platelet- and extracellular vesicle-rich plasma|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension
Status: COMPLETED
Conditions: Candidemia|Mycoses|Fungal Infection|Fungemia|Invasive Candidiasis
Interventions: DRUG: CD101|DRUG: Caspofungin|DRUG: Fluconazole|DRUG: intravenous placebo|DRUG: oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Bias Modification for Interpretation Individuals With Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Pain|Musculoskeletal Pain Disorder
Interventions: BEHAVIORAL: Benign cognitive bias modification for interpretation|BEHAVIORAL: Pain-related cognitive bias modification for interpretation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Block for Thoracic Surgery Pain
Status: COMPLETED
Conditions: Postoperative Pain|Thoracic Cancer
Interventions: PROCEDURE: serratus anterior plane block|DRUG: patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Meditation and Reiki on Assisted Reproduction Techniques Outcomes
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: Meditation presential|OTHER: Reiki|OTHER: Meditation (app)|OTHER: round of conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genicular Artery Embolization to Reduce Pain Associated With Unilateral Mild to Moderate Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: the Terumo Hydropearl® microspheres device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Climatotherapy Versus Topical Combination of Corticosteroids and Salicylic Acid in Treatment of Psoriasis
Status: UNKNOWN
Conditions: Papulosquamous Skin Disease
Interventions: DRUG: Topical corticosteroids with salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukaemia|Myeloid Malignancy
Interventions: DRUG: mitoxantrone hydrochloride liposome|DRUG: Cytarabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VERU-944 to Ameliorate Hot Flashes in Men With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Veru-944|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy
Status: ENROLLING_BY_INVITATION
Conditions: STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder|Developmental and Epileptic Encephalopathy
Interventions: DRUG: Glycerol Phenylbutyrate 1100 MG/ML [Ravicti]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Decision Assisting Tool for Prenatal Testing
Status: COMPLETED
Conditions: Pregnancy
Interventions: OTHER: Control - computerized age-appropriate prenatal testing educational brochure|OTHER: PT Tool - interactive, computerized, prenatal testing decision tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Dexamethasone Therapy in VLBW Infants at Risk of CLD
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Bronchopulmonary Dysplasia
Interventions: DRUG: Dexamethasone Early|DRUG: Dexamethasone Late
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MabionCD20® Compared to MabThera® and Rituxan® in Patients With Rheumatoid Arthritis
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: MabionCD20 (candidate biosimilar to rituximab)|BIOLOGICAL: MabThera®|BIOLOGICAL: Rituxan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Anthocyanins and Flavanols as a Strategy for a Healthy Ageing: Cardiovascular Health and Cognitive Performance
Status: COMPLETED
Conditions: Healthy Aging
Interventions: OTHER: Cocoa flavanols and berries anthocyanins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Select Indian Ragas on Electrophysiological Parameters
Status: COMPLETED
Conditions: Psychology, Social|Stress|Stress, Psychological
Interventions: OTHER: Music intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Two Most Common Ways Post-operative Eye Patch Are Therapeutic Contact Lenses (TCL) and Overnight Bandaging With Tight Bandage Patch: This Study is Designed to Determine the Most Effective Post-operative Care to Relief the Patient's Discomfort After Pterygium Excision Surgery
Status: UNKNOWN
Conditions: Pterygium of Both Eyes|Pain, Postoperative
Interventions: DEVICE: tight eye bandage|DEVICE: Soflex Soft Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Keratinized Mucosa on Peri-implant Health
Status: COMPLETED
Conditions: Keratinized Mucosa|Dental Implant|Free Gingival Graft
Interventions: PROCEDURE: Free gingival graft procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains
Status: RECRUITING
Conditions: Ankle Sprain 1St Degree|Ankle Sprain 2Nd Degree|Musculoskeletal Injury
Interventions: OTHER: Blood Flow Restriction Therapy|OTHER: Standard Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MOVIPREP® Versus NaP Pivotal Phase III Study
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: macrogol3350 NA sulphate NACL KCL ascorbic acid NA ascorbate|DRUG: Sodium Phosphate Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood-derived Mesenchymal Stem Cells in Regeneration of Sweat Glands and Body Repair
Status: UNKNOWN
Conditions: Sweat Gland Diseases
Interventions: BIOLOGICAL: UCB Mesenchymal Stem Cells treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Daclatasvir From Prodactariv 60 mg Film Coated Tablets (International Drug Agency for Pharmaceutical Industry (IDI), Egypt) and Clatazev 60 mg Tablets (Bristol-Myers Squibb Pharma, UK)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Prodactariv|DRUG: Clatazev
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of VGX-3400X, H5N1 Avian Influenza Virus DNA Plasmid + Electroporation in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: VGX-3400X
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Robotic-assisted Gait Training in Addition to a Conventional Physical Therapy in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Lokomat (Hocoma, Zurich, Switzerland)|OTHER: Conventional physical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Synera Patch Versus LMX-4 Cream Versus Placebo Patch for Pain Reduction During Venipuncture in Children
Status: COMPLETED
Conditions: Pain|Venipuncture|Anesthetics, Local
Interventions: DRUG: Synera Patch|DRUG: LMX 4 Cream|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Gain by Induction-concurrent Chemoradiotherapy and/or Accelerated Fractionation for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Adjuvant chemotherapy using PF (5-Fluorouracil )|DRUG: Induction chemotherapy using PF (5-Fluorouracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postpartum Haemorrhage (PPH) Using Misoprostol in Home Births
Status: COMPLETED
Conditions: Postpartum Haemorrhage
Interventions: DRUG: Misoprostol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Addition of MabThera (Rituximab) to Standard Treatment in Patients With Idiopathic Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: rituximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteosarcoma Metastatic|Ewing's Sarcoma Metastatic
Interventions: DRUG: Chemotherapy (gemcitabine & docetaxel) plus BIO-11006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Sham-controlled Study of Pulmonary Vein Isolation in Symptomatic Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cryoablation|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Pattern and Metabolic Health Study
Status: COMPLETED
Conditions: Diet|PreDiabetes|Weight Loss
Interventions: DIETARY_SUPPLEMENT: traditional Jiangnan diet|DIETARY_SUPPLEMENT: Mediterranean diet|DIETARY_SUPPLEMENT: Current Shanghai diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pregnancy Outcomes and Medical Costs According to Gestational Diabetes Mellitus Diagnostic Criteria
Status: UNKNOWN
Conditions: Gestational Diabetes
Interventions: DIAGNOSTIC_TEST: IADPSG Criteria|DIAGNOSTIC_TEST: NDDG Criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Trial of Zoledronic Acid to Prevent Bone Loss in Hematopoietic Cell Transplant Recipients
Status: WITHDRAWN
Conditions: Hematopoietic Stem Cell Transplant|Bone Marrow Transplant
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ConsultaTM CRT-D Clinical Evaluation Study
Status: COMPLETED
Conditions: Tachyarrhythmias|Heart Failure|Ventricular Dysfunction
Interventions: DEVICE: Bi-ventricular Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ECALMIST Versus InSurE in Preterm Infant < 32 Weeks,Multicenter, Multinational RCT
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: PROCEDURE: ECALMIST|PROCEDURE: InSure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ZEP-3Na (0.1% or 1%) Compared to Placebo in Subjects With Mild to Moderate Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: ZEP-3Na 0.1%|DRUG: ZEP-3Na 1%|DRUG: Placebo Vehicle only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: carboplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How Cagrilintide Works on the Heart Rhythm in Healthy Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Cagrilintide|DRUG: Cagrilintide Placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOTES Transvaginal Cholecystectomy and Appendectomy
Status: COMPLETED
Conditions: Gallbladder Diseases|Appendicitis
Interventions: PROCEDURE: NOTES Transvaginal Cholecystectomy|PROCEDURE: NOTES Transvaginal Appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fiasp® Versus NovoRapid® in Children With Type 1 Diabetes on MiniMed 640G Pump With Sensor
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Fiasp|DRUG: Novorapid|DEVICE: 640G pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Coronary CT-angiography and Biomarkers
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atherosclerosis
Interventions: RADIATION: Coronary CT-angiography|OTHER: Assesment of biomarkers involved in atherothrombosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Positron Emission Tomography (PET)-Computed Tomography (CT) in Inflammatory Bowel Disease (IBD)
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases
Interventions: PROCEDURE: PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of the Use of the DaVinci Robotic System for Otorhinolaryngology-Head and Neck Surgery
Status: UNKNOWN
Conditions: Head and Neck Neoplasms
Interventions: DEVICE: robot assisted endoscopic head and neck surgery using the DaVinci Robotic Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DRUG: Oral insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smart Technology for Weight Loss and Metabolic Health
Status: COMPLETED
Conditions: Obesity|Overweight|Prediabetes|Weight Loss|Lifestyle
Interventions: DEVICE: Wearable technology, smartscale|BEHAVIORAL: Smartphone applications|BEHAVIORAL: Standard Weight Management Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Implication of Omega-3 Polyunsaturated Fatty Acids in Retinopathy of Prematurity in New-born Infants
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: OTHER: RETCAM|BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Diabetes Care Through Effective Personalized Patient Portal Interactions
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: My HealtheVet Brochure|BEHAVIORAL: My HealtheVet Training Guide for Veterans Living with Diabetes|BEHAVIORAL: My HealtheVet Group Training|BEHAVIORAL: My HealtheVet Individual Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Enteral Versus Intravenous Potassium Supplementation
Status: UNKNOWN
Conditions: Acute Hypokalemia
Interventions: DRUG: Intravenous potassium chloride|DRUG: Oral potassium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of HS-25 in Chinese Adults With Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HS-25|DRUG: Placebo of HS-25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial of Endoscopic Ultrasound-Guided Bilateral Celiac Plexus Neurolysis vs Celiac Ganglia Neurolysis to Control Pain in Inoperable Pancreatic Cancer Patients With Inadequate Pain Control by Pain Killer
Status: UNKNOWN
Conditions: Pancreatic Neoplasms
Interventions: PROCEDURE: EUS-CPN|PROCEDURE: EUS-CGN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LiveWell: A Mobile Intervention for Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar I Disorder
Interventions: OTHER: Psychiatric management|BEHAVIORAL: Psychosocial treatment|BEHAVIORAL: LiveWell Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Hodgkin Lymphoma|Recurrent Childhood Hodgkin Lymphoma|Refractory Childhood Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newly Formulated, Extruded Fortified-blended Foods for Food Aid: the MFFAPP Tanzania Efficacy Study
Status: COMPLETED
Conditions: Anemia, Iron-Deficiency|Deficiency, Vitamin A
Interventions: OTHER: Corn Soy Blend Plus (CSB+)|OTHER: Corn Soy Blend 14 (CSB14)|OTHER: White Sorghum Cowpea Blend Variety 1|OTHER: White Sorghum Cowpea Blend Variety 2|OTHER: Red Sorghum Cowpea Blend|OTHER: White Sorghum Soy Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Echocardiographic Assessment of Epicardial Pacing After Cardiopulmonary Bypass.
Status: UNKNOWN
Conditions: Disorder of Pacing Function
Interventions: DEVICE: Right ventricular epicardial pacing|PROCEDURE: cardiac surgery|DEVICE: 3D TEE|DEVICE: Pacemaker lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dose-escalation Study of the Safety and Tolerability of Orally Administered TG101348 in Patients With Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: TG101348
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) and Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Cranial Electric Stimulation (CES)|DEVICE: Treadmill|DEVICE: CES and Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Replacing Diet Beverages With Water on Weight Maintenance of Type 2 Diabetic Obese Women: 18 Months Follow up
Status: COMPLETED
Conditions: Type 2 Diabetes|Overweight|Obese
Interventions: BEHAVIORAL: DBs at the end of the main meal + weight control program|BEHAVIORAL: Water at the end of the main meal+ weight control program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Metabolic Effects of Telmisartan and Amlodipine on Hypertensive Patients With Obesity and Diabetes
Status: COMPLETED
Conditions: Hypertension|Obesity|Diabetes
Interventions: DRUG: Temisartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOT vs. FLOT/Herceptin/Pertuzumab for Perioperative Therapy of HER-2 Expressing Gastric or GEJ Cancer
Status: COMPLETED
Conditions: Stomach Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: FLOT alone|BIOLOGICAL: FLOT + Herceptin/Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Disease and Outcomes Among Patients With SARS-CoV-2 Infection (COVID-19)
Status: UNKNOWN
Conditions: COVID-19 Respiratory Infection
Interventions: DIAGNOSTIC_TEST: Bloodwork, Echocardiogram, PET/MRI|DIAGNOSTIC_TEST: Bloodwork, Echocardiogram, MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduction of the Dietary Glycemic Index (GI) by L-Arabinose and Indigestible Dextrin
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: L-arabinose and indigestible dextrin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant
Status: RECRUITING
Conditions: Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Hematologic Malignancy
Interventions: DRUG: Fludarabine Phosphate|DRUG: Melphalan|RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: Total Marrow Irradiation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: 0.12% chlorhexidine mouthrinse|OTHER: Cosmetic mouthrinse|OTHER: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving the Outcomes of Adolescents With ADHD Via a Pre-visit Question Prompt List/Video Intervention
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: Question prompt list|BEHAVIORAL: Pre-visit video|BEHAVIORAL: Combined question prompt list/video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Compare the Pharmacokinetics of Budesonide Delivered by BDA MDI to Budesonide Delivered by Pulmicort Respules in Children With Asthma Aged 4 to 8 Years.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BDA MDI (PT027) 160/180 μg|DRUG: Pulmicort Respules 0.5 MG/ML Inhalation Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries
Status: UNKNOWN
Conditions: Acute Deep Partial Thickness Thermal Burns
Interventions: DEVICE: Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GI Effects of Iron in Healthy Volunteers
Status: COMPLETED
Conditions: Iron Deficiency Anemia Treatment|Microbial Colonization|Iron-deficiency|Iron Deficiency Anemia
Interventions: DIAGNOSTIC_TEST: Lactulose breath test|OTHER: Stool sample|OTHER: Daily Diary|OTHER: Irritable Bowel syndrome severity scoring system (IBS-SSS) questionnaire|DIETARY_SUPPLEMENT: Ferrous Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nab-Sirolimus in Combination With FOLFOX & BEV as 1st Line Therapy in Patients With Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: nab-sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Antitumor Activity of the Combination of Oregovomab and Hiltonol in Recurrent Advanced Ovarian Cancer
Status: TERMINATED
Conditions: Cancer of Ovary|Neoplasms, Ovarian|Ovarian Cancer Stage IV|Ovarian Cancer Recurrent|Ovarian Cancer Stage III|Ovary Cancer
Interventions: BIOLOGICAL: Oregovomab|DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energy Expenditure During Seated, Seated Cycling, and Treadmill Walking Work Conditions (EE-Work)
Status: COMPLETED
Conditions: Energy Expenditure
Interventions: OTHER: Energy Expenditure during seated in an office chair|OTHER: Energy Expenditure during seated and typing|OTHER: Energy Expenditure during Treadmill walking work condition|OTHER: Energy Expenditure during cycling work condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)
Status: UNKNOWN
Conditions: Patient Satisfaction|Vascular Access Complication
Interventions: PROCEDURE: Radial Access|PROCEDURE: State-of-the-art femoral access with 18 gauge needle|PROCEDURE: State-of-the-art femoral access with 21 gauge needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: GW856553|DRUG: GW856553|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PlasmaKinetic (PK) Button Vaporization Electrode for Treatment of Bladder Tumors
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: Monopolar electrocautery loop in Transurethral resection of bladder tumors|DEVICE: PK Button Vaporization Electrode in transurethral resection of bladder tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Propel Stent vs Kenalog-soaked Nasopore After Frontal Drill-out
Status: TERMINATED
Conditions: Stent|Sinusitis, Frontal
Interventions: DEVICE: Nasopore|DEVICE: Propel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Iron Deficiency and Chronic Heart Failure
Status: COMPLETED
Conditions: Iron Deficiency|Chronic Heart Failure
Interventions: DRUG: Ferinject (ferric carboxymaltose)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone as Add-on Treatment in Severe Fibromyalgia With Low IGF-1 Serum Levels (56 Characters)
Status: COMPLETED
Conditions: Fibromyalgia|Growth Hormone Deficiency
Interventions: DRUG: sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)|DRUG: amitriptyline, fluoxetine and tramadol alone (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal Injection
Status: ENROLLING_BY_INVITATION
Conditions: Retinitis Pigmentosa|Retinal Disease|Retinal Degeneration
Interventions: BIOLOGICAL: Gene Therapy product:vMCO-I
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Escalation and Expansion Study of SAR444200-based Regimen in Adult Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Neoplasm
Interventions: BIOLOGICAL: SAR444200|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant
Status: COMPLETED
Conditions: Liver Failure
Interventions: DRUG: Vasopressin|DRUG: Normal saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA PET Additive Value for Prostate Cancer Diagnosis in Men With Negative/Equivocal MRI
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PSMA PET/CT|PROCEDURE: Transperineal template prostate biopsy|PROCEDURE: Transperineal targeted prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-myeloid Cancer and Bone Marrow Failure Clinic Study
Status: RECRUITING
Conditions: Myeloid Malignancy|Inherited Bone Marrow Failure Syndrome|Clonal Expansion|Cytopenia|Bone Marrow Failure Syndrome|Clonal Cytopenia of Undetermined Significance|Clonal Hematopoiesis of Indeterminate Potential|Hematologic Neoplasms|Hematopoietic and Lymphatic System Neoplasm|Hereditary Neoplastic Syndrome|Idiopathic Cytopenia of Undetermined Significance|Idiopathic Dysplasia of Uncertain Significance|Low Risk Myelodysplastic Syndrome
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Punch Biopsy|PROCEDURE: Buccal Swab|OTHER: Clinical Evaluation|OTHER: Genetic Counseling|OTHER: Quality-of-Life Assessment|OTHER: Electronic Health Record Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Active Video Games for Older Adults With Knee and/or Hip Osteoarthritis.
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: Conventional physical rehabilitation plus Active video games (CPR+AVG)|OTHER: Conventional physical rehabilitation alone (CPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Human Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single & Repeat Escalating Doses of GSK2878175 in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: GSK2878175|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of Idiopathic Dilated Cardiomyopathy (Washington, DC Dilated Cardiomyopathy Study)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Myocardial Diseases|Asthma|Diabetes Mellitus|Hypertension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-inflammatory Effect of Nocturnal NIPPV on Acute Asthma
Status: COMPLETED
Conditions: Asthma Acute
Interventions: DEVICE: NIPPV|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Outcomes After Laparoscopic Intersphincteric Resection With Total Mesorectal Excision for Low Rectal Cancer.
Status: UNKNOWN
Conditions: Low Rectal Cancer
Interventions: PROCEDURE: laparoscopic intersphincteric resection|PROCEDURE: open intersphincteric resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of High Doses of Methylprednisolone in SARS-CoV2 ( COVID-19) Pneumonia Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Methylprednisolone, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Albiglutide Thorough ECG Study in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: Albiglutide|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetic Therapy in Migraine Prophylaxis
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Pulsed magnetic fields (Quantum MH-2MR bracelet)|DEVICE: Sham pulsed magnetic fields (Quantum MH-2MR bracelet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Implementing OSCE in Team Based Learning Format for Teaching Clinical Skills to Undergraduate Medical Students
Status: COMPLETED
Conditions: OSCE (Objective Structured Clinical Examination)|TBL (Team Based Learning)|Teaching Clinical Skills to Undergraduate Medical Students
Interventions: OTHER: modification of OSCE using TBL format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Oral Insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Study of the Long Term Tolerability and Safety of Atomoxetine in Children With FASD and ADD/ADHD
Status: COMPLETED
Conditions: Fetal Alcohol Syndrome|Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Vitamin D on Mineral Metabolism, Blood Pressure and Pulse Wave Analysis in Healthy Individuals
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Solid Tumor|Pediatric Lymphoma|Pediatric Brain Tumor|DIPG|Neuroblastoma|Ewing Sarcoma|Rhabdomyosarcoma|Osteosarcoma
Interventions: DRUG: CLR 131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Bacteremia
Status: TERMINATED
Conditions: Bacteremia Due to Staphylococcus Aureus
Interventions: DRUG: Daptomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunonutrition for Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetes Mellitus|Diabetic Peripheral Neuropathy|Diabetic Foot Ulcer
Interventions: DRUG: Lovaza|DRUG: L-Arginine Powder|DRUG: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis
Status: NOT_YET_RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: Human Umbilical Cord Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Green Walking on Myocardial Infarction Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Quality of Life
Interventions: OTHER: Green walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cisplatin HAI Study in Patients With Advanced Cancer and Dominant Liver Involvement
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Cisplatin|DRUG: Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Assessment of platelet reactivity|DIAGNOSTIC_TEST: Troponin measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Businesses That Care - Zacatecas
Status: COMPLETED
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Brief Intervention Motivational Interviewing (BIMI) Intervention|BEHAVIORAL: Tomando Buenas Decisiones (TBD) Intervention|BEHAVIORAL: Social Development Strategy (SDS) Intervention|BEHAVIORAL: BTC Training Session
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Infliximab for Kawasaki Disease Patients Resistant to IVIG : a Multicentre, Prospective, Randomised Trial
Status: COMPLETED
Conditions: Kawasaki Disease
Interventions: DRUG: Infliximab|DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Participants With Early Stage Coronavirus Disease 2019 (COVID-19) to Evaluate the Safety, Efficacy, and Pharmacokinetics of Remdesivir Administered by Inhalation
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Remdesivir (RDV)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid Tumours
Status: TERMINATED
Conditions: Advanced Solid Tumors|Pancreatic Cancer|CRC
Interventions: BIOLOGICAL: OMO-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Kidney Medullary Carcinoma|Metastatic Renal Cell Carcinoma|SMARCB1 Negative|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|DRUG: Ixazomib|DRUG: Ixazomib Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic and Static Stretching on Postural Stability, Reaction Time and Countermovement Jump of Sprinters
Status: COMPLETED
Conditions: Postural Stability
Interventions: PROCEDURE: Static Stretching|PROCEDURE: Dynamic Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Feasibility of an Online Intergenerational Co-parenting Program
Status: COMPLETED
Conditions: Intergenerational Relations|Perinatal Depression|Parenting
Interventions: OTHER: Usual care|OTHER: an online intergenerational co-parenting programme+usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH