pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma Bladder|Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ascending Single Oral Dose of GT-002 in Healthy Volunteers
Status: COMPLETED
Conditions: Safety and Tolerability
Interventions: DRUG: GT-002|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multimodal Physiotherapy Based on Tele-rehabilitation in Chronic Pelvic Pain Associated With Endometriosis
Status: RECRUITING
Conditions: Endometriosis|Chronic Pelvic Pain Syndrome
Interventions: OTHER: TeleRehab Group|OTHER: Advices Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation and Effectiveness of Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship
Status: COMPLETED
Conditions: Sepsis
Interventions: BEHAVIORAL: Sepsis Transition and Recovery (STAR) program|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS
Status: NOT_YET_RECRUITING
Conditions: Higher-risk Myelodysplastic Syndromes
Interventions: DRUG: Venetoclax Plus Azacytidine Conditioning Regimen Allo-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0457 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Colorectal Cancer and Other Advanced Solid Tumors (0457-001)
Status: TERMINATED
Conditions: Colorectal Cancer|Advanced Solid Tumors
Interventions: DRUG: MK0457, VX-680 (Aurora Kinase Inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Different Concentrations (0.5% and 1%) of Progesterone Topical Gel Compared to Placebo in Patients Diagnosed With Moderate to Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Pro-ocular gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LP-108 in Patients With Relapsed or Refractory B-cell Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: LP-108 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICON8: Weekly Chemotherapy in Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Chemotherapy in Gastric Cancer With Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Gastric Cancer|Peritoneal Carcinomatosis
Interventions: COMBINATION_PRODUCT: Intraperitoneal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Gastric pH on the Pharmacokinetics of Dasatinib
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dasatinib|DRUG: Dasatinib plus Rabeprazole|DRUG: Dasatinib plus Rabeprazole AND Betaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Effectiveness of Subchondroplasty for Treating Bone Marrow Lesions of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Arthroscopy|Musculoskeletal Disease|Bone Marrow Edema|Subchondral Bone Edema|Knee Osteoarthritis
Interventions: PROCEDURE: Subchondroplasty and Knee Arthroscopy|PROCEDURE: Knee Arthroscopy Alone|BIOLOGICAL: Subchondroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy for Men Undergoing Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer|Urinary Incontinence|Pelvic Floor Physical Therapy
Interventions: BEHAVIORAL: Pelvic Floor Muscle Physical Therapy|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Proprioceptive Neuromuscular Facilitation and Static Stretching Exercises
Status: UNKNOWN
Conditions: Flexibility
Interventions: PROCEDURE: Proprioceptive Neuromuscular Facilitation stretching exercise|PROCEDURE: Static stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and Safety Study of Vaginal Rings Containing Dapivirine and Levonorgestrel
Status: COMPLETED
Conditions: HIV Prevention
Interventions: COMBINATION_PRODUCT: 200 mg of DPV + 320 mg LNG|COMBINATION_PRODUCT: 200 mg of DPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Safety of a Combination Thiocolchicoside+Ketoprofen Compared to Thiocolchicoside Twice a Day for 7 Days in Patients Suffering From Acute Non Specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Thiocolchicoside+Ketoprofen|DRUG: Thiocolchicoside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Liver Function
Status: COMPLETED
Conditions: Laparoscopic Sleeve Gastrectomy
Interventions: DRUG: Total intravenous anesthesia group|DRUG: sevoflurane group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Continuous Positive Airway Pressure
Interventions: BEHAVIORAL: MET|BEHAVIORAL: ED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Skeletally Anchored Herbst Appliance in Treatment of Skeletal Class 2 Due to Mandibular Retrusion
Status: COMPLETED
Conditions: Malocclusion, Angle Class II
Interventions: DEVICE: Herbst fixed functional appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
Status: RECRUITING
Conditions: Kidney Stone
Interventions: DEVICE: vacuum assisted sheath|DEVICE: passive suction via conventional sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel 75Mg Tablet|DRUG: Rivaroxaban 2.5Mg Tablet|DRUG: Ticagrelor 90Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Drug-drug Interactions and Safety Between "BR3006-1", "BR3006-2", and "BR3006-3" in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: BR3006-1|DRUG: BR3006-2|DRUG: BR3006-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stability Of Dental Implants Placed In Healed Bony Sites Of Hyperlipidemic Patients: A Case Series
Status: UNKNOWN
Conditions: Implant Stability
Interventions: OTHER: Dental Implants Placed In hyperlipidemia patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: DRUG: Sirolimus (Rapamune)|DRUG: Cyclosporine or Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transurethral Modified En Bloc Resection For Large Bladder Tumours.
Status: RECRUITING
Conditions: Bladder Cancer|Bladder Neoplasm|Bladder Tumor
Interventions: DEVICE: Bipolar transurethral modified en bloc resection of bladder tumour
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Microprocessor-controlled Prosthetic Knee-ankle System (SPCM)
Status: COMPLETED
Conditions: Amputation|Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: SPCM|DEVICE: Usual Prothesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics on Stress-associated Gastrointestinal Function in University Students
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic Combination|DIETARY_SUPPLEMENT: Bifidobacterium bifidum|DIETARY_SUPPLEMENT: Bifidobacterium longum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: iCanCope With Pain: Usability and Feasibility Testing of a Smartphone Application to Manage Pain in Youth With Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: iCanCope app|BEHAVIORAL: iCanCope attention control app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Second-line Therapy of Unresectable Cholangiocarcinoma by RADIOEMBOLIZATION
Status: TERMINATED
Conditions: Cholestasis, Progressive Familial Intrahepatic 3
Interventions: DEVICE: Yttrium microsphere injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Camrelizumab Combined With SOX in the Adjuvant Treatment of Advanced Gastric Adenocarcinoma or Gastric Esophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Camrelizumab Combined with SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroid Withdrawal Intervention in Fife and Tayside
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: ICS withdrawal protocol|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Abdominal Perfusion Pressure in Septic Shock
Status: TERMINATED
Conditions: Acute Kidney Injury|Septic Shock|Resuscitations
Interventions: DEVICE: Abdominal Perfusion Pressure (APP)|DEVICE: Mean Arterial Pressure (MAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprapostural Attention Focus and Postural Difficulty on H-reflex and Brain Activity: Aging and Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson
Interventions: BEHAVIORAL: stable condition|BEHAVIORAL: unstable condition|BEHAVIORAL: attentional focus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bupropion for Smoking Cessation During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related|Tobacco Use Disorder
Interventions: DRUG: Bupropion SR|BEHAVIORAL: Smoking Cessation Counseling|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: ridaforolimus|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Heart Health in Appalachia
Status: COMPLETED
Conditions: Obesity|Hypertension|Hyperlipidemia|Depression
Interventions: BEHAVIORAL: Self-care CVD risk reduction|OTHER: Referral to primary care provider for CVD risk management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GW685698X 100mcg Administered Once Daily Either in the Morning or the Evening and GW685698X 250mcg Administered Once Daily in the Evening Via DISKHALER for 28 Days in Subjects With Persistent Bronchial Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW685698X (fluticasone furoate) 100mcg Morning|DRUG: GW685698X (fluticasone furoate) 100mcg Evening|DRUG: GW685698X (fluticasone furoate) 250mcg Evening|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Airway Pressure on Pleural Effusion After Drainage
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: DEVICE: Positive Airway Pressure|OTHER: Conventional Chest Physiotherapy|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diuretics In the Management of Essential Hypertension (DIME) Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Thiazide diuretics|DRUG: No diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Closed-loop Control of Glucose Levels in the Context of Exercise in Adults With Type-1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Conventional continuous subcutaneous insulin infusion therapy|DEVICE: Dual-hormone closed-loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Fit Iterative App Development
Status: RECRUITING
Conditions: Weight Gain Prevention|Physical Inactivity
Interventions: BEHAVIORAL: Family Fit Condition|BEHAVIORAL: Fitbit Only Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Pd-103 with 20 vs 44 Gy supplemental beam XRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorambucil + Lenalidomide and Lenalidomide Maintenance in Untreated Elderly With Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide; Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With Moderately Infected Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: gentamicin-collagen sponge and levofloxacin|DRUG: Levofloxacin only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Verify if Marrow Venting Procedure Can Improve Meniscal Suture Healing
Status: RECRUITING
Conditions: Meniscal Tear
Interventions: PROCEDURE: Meniscal repair|PROCEDURE: Marrow venting procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes & Vardenafil
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)|Endothelial Dysfunction|Erectile Dysfunction
Interventions: DRUG: Vardenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Platelet Rich FibrinDuring Clear Aligner Therapy
Interventions: BIOLOGICAL: iPRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Energy Dispersive Bracing for Conservative Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthritis
Interventions: OTHER: Exercise Only|DEVICE: Brace Only|OTHER: Bracing + Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gfree - For Improved Blood Sugar and Reduced Inflammation.
Status: RECRUITING
Conditions: Diabetes|Celiac Disease|Autoimmunity|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: gluten-free|DIETARY_SUPPLEMENT: probiotic|DIETARY_SUPPLEMENT: gluten
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of Intravenous Aflibercept in Combination With Docetaxel in Japanese Cancer Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: aflibercept (AVE0005)|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vandetanib to Treat Children and Adolescents With Medullary Thyroid Cancer
Status: COMPLETED
Conditions: Medullary Thyroid Carcinoma|Multiple Endocrine Neoplasia Type 2A|Multiple Endocrine Neoplasia Type 2B
Interventions: DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Treatment of Depression in Parkinson's Disease
Status: UNKNOWN
Conditions: Major Depressive Disorder|Parkinson's Disease
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Laughter Yoga Program in Adolescents With Disabilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Disability, Adolescent Learning|Psychosocial Problem
Interventions: BEHAVIORAL: Laughter yoga programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: dextromethorphan|DRUG: naloxone|DRUG: fentanyl|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Anti-PD-1 Monoclonal Antibody HX008 Injection for the Treatment of Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of COVID-19 Vaccine (ABNCoV2)
Status: COMPLETED
Conditions: Covid19|Severe Acute Respiratory Syndrome|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: ABNCoV2 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Low-Calorie Diet and Lifestyle Intervention on Reversal of T2DM
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|PreDiabetes|Diet Habit
Interventions: DIETARY_SUPPLEMENT: CURE-DM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Effectiveness and Safety of the Single-port Robotic-assisted Breast Surgery in Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: single-port robotic-assisted nipple-sparing mastectomy and sentinel lymph node biopsy|PROCEDURE: single-port robotic-assisted nipple-sparing mastectomy and axillary lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal-Hope Study: Home Monitoring of Fetal Heart Rate in SSA+ Pregnant Women
Status: RECRUITING
Conditions: Pregnancy Related|Autoimmune Diseases|Neonatal Lupus|SLE|Sjogren's Syndrome|Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Confirm the Safety and Efficacy of Epoetin Alfa (PROCRIT) Administered Perioperatively vs. the Standard of Care in Blood Conservation in Patients Undergoing Major Elective Spinal Surgery (SPINE Study)
Status: COMPLETED
Conditions: Anemia|Venous Thrombosis
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Adhesion Strategies on the Clinical Success
Status: NOT_YET_RECRUITING
Conditions: Poor Aesthetic of Existing Restoration of Tooth|Dental Restoration Failure of Marginal Integrity|Unacceptable Morphology of Tooth Restoration|Secondary Caries
Interventions: PROCEDURE: Treatment of cervical lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate (Ritalin®) Effect During Exposure to Exercise and Heat Stress in ADD/ADHD Treated Patients
Status: UNKNOWN
Conditions: Methylphenidate
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lung Recruitment Assessment With Lung Ultrasound In Pediatric Patient Scheduled For Laparoscopic Surgery
Status: COMPLETED
Conditions: Atelectasis
Interventions: OTHER: Lung recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Diet- and Exercise- Related Weight Control Intervention Program on Obesity in Adult Aged 40 and Over
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: BEHAVIORAL: Individualized education|BEHAVIORAL: Grouped education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cold Liquids Fed to Preterm Infants: Efficacy and Safety After 10 Minutes of Exposure
Status: COMPLETED
Conditions: Deglutition Disorders|Respiratory Aspiration
Interventions: OTHER: Cold Liquid Barium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Block Versus Non-targeted Local Anaesthesia in Breast Surgery
Status: UNKNOWN
Conditions: Pain, Post Operative
Interventions: OTHER: targeted chirocaine pec block|OTHER: standard chirocaine infiltration|OTHER: standard post-operative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-018 in Preventing the Recurrence of Crohn's Disease After Surgery
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: TAK-018|DRUG: TAK-018 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bloodstream Absorption of Avastin and Lucentis After Injection Into the Eye
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Bevacizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Loratadine / Pseudoephedrine Sulfate 10/ 240 mg Extended-Release Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 10 mg Loratadine/240 mg Pseudoephedrine Sulfate Extended-Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Vaginal Cuff Dehiscence and Thermal Injury During TLH
Status: COMPLETED
Conditions: Vaginal Cuff Dehiscence|Thermal Injury
Interventions: PROCEDURE: Cut-Coag|PROCEDURE: V-mode|DEVICE: Valleylab G3000 Electrosurgical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Interactive Advance Care Planning Intervention to Facilitate a Good Death for Cancer Patients
Status: COMPLETED
Conditions: End Stage Cancer
Interventions: BEHAVIORAL: Interactive advance care planning|BEHAVIORAL: Attention usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM)
Status: COMPLETED
Conditions: Subdural Hematoma, Chronic
Interventions: DEVICE: SQUID Embolization|DEVICE: SQUID Embolization and Surgical Evacuation|PROCEDURE: Surgical Evacuation|OTHER: Other: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome, Newborn|Transient Tachypnea of the Newborn
Interventions: DRUG: Betamethasone|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
Status: RECRUITING
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Transdiagnostic Behavior Therapy|BEHAVIORAL: Cognitive Behavioral Therapy for Social Anxiety Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia
Status: TERMINATED
Conditions: Anemia|Liver Disease|Hypoxemia
Interventions: DRUG: Pegylated Interferon Alpha2b|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial Evaluating Axitinib In Patients With Unresectable, Recurrent Or Metastatic Head And Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Axitinib (AG-013736)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin
Status: COMPLETED
Conditions: Fredrickson Type IIa & Type IIb Dyslipidaemia
Interventions: DRUG: Rosuvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levosimendan Versus Dobutamine in Cardiopatic Patients Undergoing Major Non Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: Levosimendan|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Discussion|OTHER: Interview|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Idarubicin Versus High Dose Daunorubicin in Acute Myelogenous Leukemia (AML)
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Cytarabine plus Daunorubicin [Arm II (AD regimen)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Relationship Between the Duration of the Evolution of the Complex Regional Pain Syndrome Type 1 (CRPS 1) and Effectiveness of the Continuous Peripheral Nerve Block (CPNB) Associated With an Intensive Rehabilitation Program
Status: UNKNOWN
Conditions: CRPS (Complex Regional Pain Syndrome) Type I
Interventions: PROCEDURE: Intensive rehabilitation program with CPNB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Milk Thistle Clinical Trial in Pediatric NAFLD
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: Milk thistle (MT)|DRUG: Placebo|BEHAVIORAL: Lifestyle Modification|DEVICE: Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trama-Code (Two Analgesics-comparative Study)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ixprim®|DRUG: Dafalgan-Codeine®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clindamycin Once a Day in Septic Abortion
Status: UNKNOWN
Conditions: Septic Abortion
Interventions: DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy in Naturally Menopausal Women With Low Sexual Desire Receiving Transdermal Estrogen
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin D on Top of Pegylated Interferon and Ribavirin in Patients With Chronic Viral Hepatitis C Null-Responders
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Anti-PD-1 in R/R DLBCL
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Relapse/Recurrence|Extranodal Extension|Central Nervous System Lymphoma
Interventions: DRUG: Low-Dose Decitabine plus anti-PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Fraction HDR Brachytherapy Plus Hypofractionated EBRT for Low-risk Prostate Cancer: Phase II Trial
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: RADIATION: HDR brachytherapy + hypofractionated EBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Conservative Treatment on Gait Biomechanics in Adolescent Idiopathic Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis|Gait Disorder, Sensorimotor
Interventions: OTHER: Moor S brace treatment|OTHER: Schroth Three-Dimensional Scoliosis Exercise Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control
Status: WITHDRAWN
Conditions: Essential Arterial Hypertension
Interventions: DRUG: Candesartan + Chlorthalidone|DRUG: Candesartan + Chlorthalidone|DRUG: Losartan+hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Combined LED Light for the Treatment of Mild to Moderate Plaque Type Psoriasis Vulgaris
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DEVICE: Dermawrap - combined 460nm, 633nm and 830nm LED therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate HT-6184 in Healthy Subjects
Status: COMPLETED
Conditions: Normal Healthy Subjects
Interventions: DRUG: HT-6184|DRUG: HT-6184 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Bardoxolone Methyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Bilateral Erector Spinae Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Status: RECRUITING
Conditions: Erector Spinae Block|Analgesia|Scoliosis Idiopathic
Interventions: PROCEDURE: erector spinae block|PROCEDURE: sham bilateral ultrasounded guided erector spinae block|DRUG: normal saline|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Head to Head Comparison of Two Needles EUS Guided FNB
Status: WITHDRAWN
Conditions: Pancreatic Tumor
Interventions: DEVICE: Ultrasound biopsy needle Echo Tip ProCore|DEVICE: Ultrasound biopsy needle SharkCore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Relief - Tramadol Versus Ibuprofen
Status: UNKNOWN
Conditions: Choroidal Melanoma|Melanoma|Eye Neoplasms
Interventions: DRUG: Ibuprofen|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension), Administered to Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: CRPC|Prostate Cancer
Interventions: DRUG: BIND-014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lipid Emulsions on Free Fatty Acids and Free Bilirubin in Premature Newborns
Status: COMPLETED
Conditions: Prematurity
Interventions: DRUG: Intralipid, 20% Intravenous Emulsion|DRUG: SMOF lipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AK104 Combined With Chemotherapy and Recombinant Human Adenovirus 5 Injection in Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer Recurrent
Interventions: DRUG: AK104|DRUG: Recombinant Human Adenovirus 5 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of TV-44749 in Chinese Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: TV-44749|DRUG: Oral Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colchicine Versus Placebo in Acute Myocarditis Patients
Status: RECRUITING
Conditions: Acute Myocarditis
Interventions: DRUG: Colchicine Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients
Status: UNKNOWN
Conditions: Post Polypectomy Bleeding in Anticoagulated Patients|Gastrointestinal Hemorrhage
Interventions: DRUG: Warfarin|DRUG: LMW Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Assay for the Pancreatic Polypeptide: an Help for Clinical Practice Guidelines in Classification of the Diabetes
Status: COMPLETED
Conditions: Type1diabetes
Interventions: OTHER: 12 ml total blood tubes volume|OTHER: Fecal sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Intestinal Vascolarization With Indocianine Green Angiography During Rectal Resection or Left Colectomy
Status: COMPLETED
Conditions: Rectal Disease|Sigmoid Disease
Interventions: PROCEDURE: ICG- angiography|PROCEDURE: No angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Genotype-guided Treatment in DLBCL
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Orelabrutinib|DRUG: Lenalidomide|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NewishT Cell Therapy for HCC With High Risk of Recurrence After Radical Resection
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Autologous memory lymphocyte Injection (NewishT), low-dose group|DRUG: Autologous memory lymphocyte Injection (NewishT), high-dose group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 0.5% Carboxymethylcellulose With 0.005% Stabilized Oxychlorocomplex (PURITE™) Versus 0.5% Carboxymethylcellulose in the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: 0.5% carboxymethylcellulose (CMC) with purite and CMC alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Glycemic and Insulinemic Impact of Oats With Additional Dried Fruits, Nuts and Seeds Soaked Overnight
Status: COMPLETED
Conditions: Blood Glucose; Subjective Hunger, Insulin
Interventions: OTHER: Overnight oats with additional dried fruits, nuts and seeds|OTHER: Cooked cream of rice with additional dried fruits, nuts and seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line Treatment for Myeloma
Status: SUSPENDED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Single ASCT with Thalidomide maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety of the Drug BAY2395840 at Different Doses, the Way the Body Absorbs, Distributes and Excretes the Drug Including the Effect of Its Formulation (Tablet or Liquid) and the Effect of Food on the Absorption, Distribution or Excretion of the Drug in Healthy Male Participants
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: BAY2395840 tablet|DRUG: BAY2395840 oral solution|DRUG: Placebo oral solution|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Ascending Dose Study to Evaluate M281 Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: M281|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Dietary Intervention on Children of ADHD at Sohag University Hospital
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet|DIETARY_SUPPLEMENT: Usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Monitoring and Improvement of Adherence to DOACs in Polymedicated Stroke Patients
Status: COMPLETED
Conditions: Adherence, Patient|Stroke, Ischemic
Interventions: BEHAVIORAL: Medication intake reminders|BEHAVIORAL: Pillbox use and counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of the Effects of Different Exercise on Wound Healing in Patients wıth Diabetic Foot Wounds
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Wound
Interventions: OTHER: standard treatment|OTHER: aerobic exercise|OTHER: exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment by Therapeutic Body Wraps in Children and Adolescents Suffering From Autism With Severe Injurious Behavior.
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Dry sheet Therapeutic body wraps|OTHER: WET sheet Therapeutic body wraps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protocol to Validate the Performance of the LifeKit® Prevent Colorectal Neoplasia Test for CRC Screening
Status: UNKNOWN
Conditions: Colorectal Cancer|Colorectal Adenoma
Interventions: DIAGNOSTIC_TEST: LifeKit Prevent Colorectal Neoplasia Test|DIAGNOSTIC_TEST: FIT Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaginal Cuff Brachytherapy Followed by Chemotherapy in Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Papillary Serous|Clear Cell Endometrial Cancer
Interventions: RADIATION: Vaginal Cuff Brachytherapy|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT