pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: HIPEC Combined With Sintilimab for Gastric Cancer With Peritoneal Metastasis
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: HIPEC,anti-PD-1 antibody Sintilimab (Tyvyt®), Chemotherapy,Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The 'Hidden' Biological Impact of Vitamin D Deficiency: a Biomarker Study; Part 2
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VIA Disc NP Pilot for Patients With Symptomatic Degenerated Discs
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease|Low Back Pain|Disc Degeneration
Interventions: OTHER: VIA Disc NP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Treatment of Permanent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Surgical bipolar radiofrequency ablation using the AtriCure Bipolar System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rebeccamycin Analog as Second-Line Therapy in Treating Patients With Limited-Stage or Extensive-Stage Small Cell Lung Cancer That Relapsed After Previous First-Line Chemotherapy
Status: TERMINATED
Conditions: Extensive Stage Small Cell Lung Cancer|Limited Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: DRUG: becatecarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Assessment for Early Identification of Supportive Care Needs in Oncology Patients
Status: NOT_YET_RECRUITING
Conditions: Oncology
Interventions: OTHER: QoL questionnaires|OTHER: Qualitative Interview (for one part of nurses only)|OTHER: ORIC questionnaire|OTHER: Professionals satisfaction survey|OTHER: Patients satisfaction survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect and Applicability of CBT-Based Weight Loss Treatment Model in Obese Patients With Comorbid Depression in Health Care
Status: RECRUITING
Conditions: Obesity|Depression|Cognitive Behavioral Therapy|Weight Loss
Interventions: BEHAVIORAL: CBT-based weight loss model|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Vaccination: An Investigation of Physician Reminders and Recommendation Scripts
Status: COMPLETED
Conditions: Human Papilloma Virus Infection Type 11|Human Papilloma Virus Infection Type 16|Human Papilloma Virus Infection Type 18|Human Papilloma Virus Infection Type 6|Cervical Cancer|Genital Warts|Oropharyngeal Cancer
Interventions: BEHAVIORAL: Automated Reminder|BEHAVIORAL: Automated Reminder Plus Script
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: INIT Versus IASTM In Patients With Chronic PF
Status: NOT_YET_RECRUITING
Conditions: Planter Fasciitis
Interventions: OTHER: integrated neuromuscular inhibition technique|OTHER: instrument assissted soft tissue mobilization|OTHER: convential treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Induction of Labor in Patients With Unfavorable Cervical Conditions
Status: COMPLETED
Conditions: Unfavorable Cervix for Induction of Labor
Interventions: DEVICE: ARD (Atad Ripener Device)|DEVICE: AID (Atad double balloon Instillation Device)|DEVICE: folly catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of LNK01004 Ointment in Adults With Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: LNK01004 ointment 0.3%|DRUG: LNK01004 ointment 1.0%|DRUG: LNK01004 ointment 1.5%|DRUG: Vehicle BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAVATAK® and Ipilimumab in Uveal Melanoma Metastatic to the Liver (VLA-024 CLEVER)
Status: COMPLETED
Conditions: Uveal Melanoma|Liver Metastases
Interventions: BIOLOGICAL: CVA21|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: CC-486
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells for the Induction of Remission in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Allogeneic adipose tissue-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining Stress REsilience And Mindfulness Effects in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: BEHAVIORAL: Mindfulness Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Immunogenicity and Safety of GSK Biologicals' Influenza Vaccine FLU-Q-QIV in Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FLULAVAL® QUADRIVALENT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotics on Immunosuppressive-drug-associated Diarrhea Among Renal Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Renal Transplantation
Interventions: OTHER: Florajen Digestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Phosphorus on Diet Induced Thermogenesis
Status: COMPLETED
Conditions: Imbalance of Constituents of Food Intake|Healthy
Interventions: DIETARY_SUPPLEMENT: Phosphorus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Hypofractionated Radiation Therapy or Conventional Radiation Therapy After Surgery in Treating Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Adenocarcinoma|Stage II Prostate Adenocarcinoma|Stage III Prostate Adenocarcinoma
Interventions: RADIATION: Hypofractionated radiation therapy|RADIATION: Conventional radiation therapy|DRUG: Optional androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reliability of Hand Held Dynamometer for Assessing Isometric Lumbar Muscle Strength in Asymptomatic Healthy Population
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: MicroFET 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Nicotine Replacement Treatment for Pregnant Smokers - 1
Status: TERMINATED
Conditions: Tobacco Use Disorder
Interventions: DRUG: placebo|DRUG: 2 mg nicotine polacrilex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Head and Neck Position on the Oropharyngeal Leak Pressure Using Air-Q SP Airway
Status: COMPLETED
Conditions: General Anesthesia
Interventions: PROCEDURE: Neutral head position|PROCEDURE: Flexed head position|PROCEDURE: Extended head position|PROCEDURE: Rotated head position|DEVICE: Air-Q SP Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of B6 and Metoclopramide Combination in Comparison With the Other Antiemetics
Status: COMPLETED
Conditions: Vomiting
Interventions: DRUG: Metoclopramide and Vitamin B6|DRUG: Vitamin B6|DRUG: Ondansetron|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DIAGNOSTIC_TEST: Respiratory Muscle Strength|DEVICE: Balance Training|DEVICE: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Sympathetic Tone Regarding the Anatomical and Functional Recovery of the Left Ventricle in TakoTsubo Syndrome
Status: UNKNOWN
Conditions: Takotsubo Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: 123 MIBG scintigraphy testing|DIAGNOSTIC_TEST: MSNA|DIAGNOSTIC_TEST: ABPM|DIAGNOSTIC_TEST: ECHO|DIAGNOSTIC_TEST: 24hour ECG|DIAGNOSTIC_TEST: CMR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Refining Novel Culturally Tailored Behavioral Weight Loss Treatment Components for Sexual Minority Women With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Weight Loss Intervention|BEHAVIORAL: Minority Stress Intervention|BEHAVIORAL: Negative Body Image Intervention|BEHAVIORAL: Social Support Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of De-Prescribing Antipsychotics on Health and Quality of Life for People With Dementia
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Prescribing, Off-Label
Interventions: BEHAVIORAL: Overprescribing letter to attributed physician|BEHAVIORAL: Placebo letter to attributed physician
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease With Cognitive Impairments
Interventions: DRUG: safinamide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Refractive Ametropia
Interventions: DEVICE: Serafilcon A contact lenses|DEVICE: Senofilcon A contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Therapy of Early Cancer in Barretts Esophagus
Status: COMPLETED
Conditions: Early Stage Esophageal Adenocarcinoma|Barrett Esophagus
Interventions: PROCEDURE: Endoscopic Mucosal Resection|PROCEDURE: Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Microbiota and Quality of Life in IBS
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: a supplement containing 2'-fucosyllactose (2'-FL)|DIETARY_SUPPLEMENT: Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Prevention and Treatment of Dry Eye in Patients Using Glaucoma Drops
Status: UNKNOWN
Conditions: Dry Eye|MGD-Meibomian Gland Dysfunction
Interventions: DRUG: 0.3% sodium hyaluronate ophthalmic solution|DRUG: 0.1% sodium bromide solution|OTHER: Meibomian gland massage|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ceftobiprole in the Treatment of Patients With Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Ceftobiprole medocaril|DRUG: Ceftriaxone with or without Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retorna Facial Cream in the Treatment of Facial Wrinkles
Status: COMPLETED
Conditions: Facial Wrinkles
Interventions: OTHER: Retorna|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-686117 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: BMS-686117|DRUG: Byetta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Safe BAY2586116 is, How it Affects the Body, How it Moves Into, Through and Out of the Body at Different Doses in Healthy Japanese Male Participants After Taking Single and Multiple Doses Through the Nose
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: BAY2586116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of 5% Dextrose Water Versus Corticosteroid Injection for Pain Management of SJD
Status: ACTIVE_NOT_RECRUITING
Conditions: Sacroiliac Joint Dysfunction
Interventions: COMBINATION_PRODUCT: Dextrose Water|COMBINATION_PRODUCT: Corticosteroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Spleen-Preserving No. 10 Lymph Node Dissection in Gastric Cancer
Status: UNKNOWN
Conditions: Overall Survival
Interventions: PROCEDURE: D2 Lymphadenectomy including No. 10|PROCEDURE: D2 lymphadenectomy excluding No. 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Reliability of Expressed Prostatic Secretion (EPS) and Post Massage Urine (PMU) for the Prediction of Prostate Cancer Biopsy Outcome
Status: ACTIVE_NOT_RECRUITING
Conditions: Conditions Influencing Health Status|Healthy|Prostate Cancer
Interventions: OTHER: laboratory biomarker analysis|PROCEDURE: transrectal prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell Tumors
Status: RECRUITING
Conditions: Non-Seminomatous Germ Cell Tumor
Interventions: DRUG: BEP Protocol|DRUG: Dose-dense regimen|PROCEDURE: Early tumor resection or HD-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine in Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Management Modified Cardiac Rehabilitation in Patients After Acute Myocardial Infarction or Heart Failure
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Heart Failure
Interventions: BEHAVIORAL: Modified CR|BEHAVIORAL: Traditional CR|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy
Status: COMPLETED
Conditions: Cardiomyopathies|Heart Failure, Congestive|Dyspnea, Paroxysma
Interventions: DRUG: Natrecor (nesiritide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Lucerastat (OGT 923) in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Lucerastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care
Status: COMPLETED
Conditions: Respiration
Interventions: DEVICE: Triggering mode of the ventilator|DEVICE: Triggering method of the ventilator|DEVICE: Triggering method of the ventilator|DEVICE: Triggering method of the ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
Status: COMPLETED
Conditions: Metastatic Hepatocellular Carcinoma|Advanced Liver Cancer
Interventions: DRUG: Ascorbic Acid + Sorafenib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Intervention in Respiratory Inpatients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma|Community Acquired Pneumonia
Interventions: DRUG: Varenicline|BEHAVIORAL: Behavioral support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Value of Adding Dapagliflozin in Patients With Nephrotic Syndrome
Status: COMPLETED
Conditions: Nephrotic Syndrome|Sodium-Glucose Transporter 2 Inhibitors
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Mannitol|DRUG: Menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of EPBD in ERCP on the Prognosis of Patients With Choledocholithiasis Complicated With Duodenal Papillary Diverticula
Status: UNKNOWN
Conditions: Periampullary Diverticula
Interventions: PROCEDURE: EPBD|PROCEDURE: EST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Study of the Role of the Immune Response, in Relation to Diet, in Patients Affected by Either Chronic Hepatitis C Virus (HCV) Infection or Non Alcoholic Fatty Liver Disease (NAFLD)
Status: UNKNOWN
Conditions: Chronic Hepatitis C Virus|Non Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: normocaloric low cholesterol diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Linear and Macrocyclic Gadolinium Based Contrast Agents for Patients With Mild to Moderate Renal Insufficiency Undergoing Enhanced Magnetic Resonance Imaging
Status: UNKNOWN
Conditions: Nephrogenic Fibrosing Dermopathy
Interventions: DRUG: Gadodiamide|DRUG: Gadoteric Acid Meglumine Salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Acetaminophen Preemptive Analgesia on Postoperative Cognitive Function
Status: RECRUITING
Conditions: Cognitive Function
Interventions: DRUG: acetaminophen mannitol|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Non Invasive Mechanical Ventilation on Tissue Perfusion in Patients After Cardiac Surgery
Status: COMPLETED
Conditions: Heart Diseases|Coronary Artery Disease
Interventions: OTHER: Noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficacy and Safety of the Dosage Adjustment of Aprovel® (Irbesartan) in Hypertensive Outpatients in Current Clinical Practice
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: transcranial direct current stimulation and naming training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver
Status: COMPLETED
Conditions: Liver Neoplasms|Neoplasm Metastasis
Interventions: PROCEDURE: Isolated hepatic portal and arterial perfusion|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Blood-Brain Barrier opening with MRgFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 10d TL quadruple therapy|DRUG: 10d AL quadruple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaborative Italian-American Clinical Trial of Nutritional Supplements and Age-related Cataract (CTNS)
Status: COMPLETED
Conditions: Cataract
Interventions: DIETARY_SUPPLEMENT: Centrum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Abdominal Incompetence on Urinary Incontinence After Prostatectomy (PROSTABDO)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: evaluation of deep abdominal wall before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Time-Restricted Eating and Mindfulness-Based Stress Reduction to Reduce the Risk of Early-Onset Colorectal Cancer
Status: COMPLETED
Conditions: Obesity|Colorectal Cancer|Microbial Colonization|Time Restricted Feeding|Stress, Psychological
Interventions: BEHAVIORAL: TRE|BEHAVIORAL: MBSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ACT-DE for Diabetes Distress in Adults With Type 2 Diabetes: A Pilot RCT
Status: COMPLETED
Conditions: Acceptance and Commitment Therapy|Type 2 Diabetes|Diabetes Distress
Interventions: BEHAVIORAL: ACT-DE|BEHAVIORAL: DE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Pregnancy Outcomes
Status: COMPLETED
Conditions: Maternal Vitamin D Status
Interventions: DIETARY_SUPPLEMENT: vitamin D3 (1000 IU)|DIETARY_SUPPLEMENT: Vitamin D3 (2000 IU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma
Status: COMPLETED
Conditions: Leiomyosarcoma|Uterine Neoplasm
Interventions: DRUG: gemcitabine, docetaxel, doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Hematological Malignancies
Status: RECRUITING
Conditions: Relapsed/Refractory Hematological Malignancies|Lymphoma|Myeloma|Leukemia
Interventions: BIOLOGICAL: Autologous CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma-Adapted First-Line Pembro In NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC Stage IV|Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: PEMETREXED|DRUG: CARBOPLATIN|DRUG: PACLITAXEL|DIAGNOSTIC_TEST: InVision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crisaborole for Chinese and Japanese Subjects (≥2 Years of Age) With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole Ointment|DRUG: Crisaborole Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Placebo Controlled Pilot Study of Probiotic Supplementation in At-risk Pregnant Women
Status: COMPLETED
Conditions: Iron-deficiency|Pregnancy, High Risk|Stress, Psychological
Interventions: DIETARY_SUPPLEMENT: Probiotic LP299v 10x10 colony forming units in capsule form|OTHER: Placebo in capsule form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Rituximab and Lenalidomide Treatment for Untreated Patients With Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Rituximab-CHOP|DRUG: Rituximab-CVP|DRUG: Rituximab-Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Visual Cues in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Movement Disorders|Gait Disorders, Neurologic
Interventions: DEVICE: QWalk Study Group|OTHER: Traditional visual cues - Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 3,5-Diiodothyropropionic Acid (DITPA) in Hypercholesterolemic Patients
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: 3,5-Diiodothyropropionic acid (DITPA) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Influence of a Food Supplement on the Gut Microbiome in Healthy Obese Women
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Strath® Kräuterhefe Original (liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Model-based Cardiac Rehabilitation on Self-care, Quality of Life, and Self-efficacy in Patients With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Self Care
Interventions: BEHAVIORAL: transtheoretical model-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Mountain Craft Training at Enhancing the Resilience and Physio-psychological Well-being of Children From Low-income Families
Status: RECRUITING
Conditions: Resilience|Well-being|Children
Interventions: OTHER: Intervention|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Effect of JNJ-28431754 (Canagliflozin) on Post-Meal Glucose in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Canagliflozin 300mg/Placebo|DRUG: Canagliflozin 300mg/Canagliflozin 150mg|DRUG: Canagliflozin 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures
Status: TERMINATED
Conditions: Non-alcoholic Steatohepatitis|Chronic Liver Disease|HCV|NASH - Nonalcoholic Steatohepatitis|HIV Infection|Thrombocytopenia|Hepatitis C Virus|HBV|Human Immunodeficiency Virus|Liver Diseases|Hepatitis B Virus
Interventions: DRUG: Eltrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opportunistic Screening for Osteoporotic Vertebral Fractures in Patients With Diffuse Interstitial Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis|Interstitial Lung Disease|Vertebral Fracture
Interventions: OTHER: Chest CT Scan examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Traditional Rehabilitation Versus Rehabilitation With the Imoove® Device for Spinal Musculoskeletal Disorders
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: OTHER: Routine Physical Therapy|DEVICE: I-Moove Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Novel Silq ClearTract Catheter in Patients With Chronic Urinary Retention
Status: RECRUITING
Conditions: Catheter Infection|Catheter Blockage|Catheter Related Complication|Catheter Calcification
Interventions: DEVICE: SILQ ClearTract 100% Silicone 2-Way Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Vitamin D on 25-hydroxyvitamin D Levels and Physical Function
Status: COMPLETED
Conditions: Vitamin D Deficiency|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: PEP (Purified Exosome Product) / TISSEEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Nutritional Adequacy of a New Infant Formula in Healthy Term Infants
Status: UNKNOWN
Conditions: Child Development
Interventions: DIETARY_SUPPLEMENT: Oral feeding of Feihe Stage 1 infant formula|DIETARY_SUPPLEMENT: Oral feeding of control Stage 1 formula|DIETARY_SUPPLEMENT: Breast feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A.
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection|DRUG: Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Biological Effect on Wound Healing of ILP100-Topical in Subjects With Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Wound Heal|Wound Healing Disturbance of|Wound Healing Disorder|Wound Healing Delayed|Diabetic Foot Ulcer|Diabetic Foot Ulcer Mixed
Interventions: BIOLOGICAL: ILP100-Topical (emilimogene sigulactibac) 5x10^7 CFU/cm^2|BIOLOGICAL: ILP100-Topical (emilimogene sigulactibac) 1x10^9 CFU/cm^2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Intestinal Flora in the Pathogenesis of FD and the Intervention of Xiangsha Liujunzi
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Xiangsha Liujunzi granules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Supplementation With Low-Dose Omega-3 Reduces Salivary TNF-α Levels in Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Placebo|PROCEDURE: Omega-3|PROCEDURE: SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy of Thick Shell Mussel Lipid Extract in Chinese Subjects With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Mussel oil capsules|DIETARY_SUPPLEMENT: Corn oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma.
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: GEMBRAX|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Polysomnography (PSG)|DIAGNOSTIC_TEST: Rectal thermistor 400 Series|OTHER: Bright blue-green light|OTHER: Dim red light|DIAGNOSTIC_TEST: Digital foot candle datalogging light meter|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function|OTHER: Pittsburgh Sleep Quality Index (PSQI)|OTHER: Center for Epidemiological Studies - Depression|OTHER: Montreal Cognitive Assessment (MoCA)|OTHER: European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30)|OTHER: Daily Log
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety of Non-vitamin K Oral Anticoagulants Compared to Warfarin Early After Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Non-vitamin K oral anticoagulants (NOACs)|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma|Unresectable Pancreatic Carcinoma|Stage III Pancreatic Cancer AJCC v6 and v7|Stage IV Pancreatic Cancer AJCC v6 and v7
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|DRUG: Metformin Hydrochloride|DIETARY_SUPPLEMENT: Therapeutic Dietary Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cystocele Repair With Trans Obturator Tape VS. Trans Obturator Tape Alone on Stress Urinary Incontinence.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Trans Obturator Tape Procedure (TOT)|PROCEDURE: Cystocele Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Multiple Nasal Exposures to House Dust Mite Allergen on Nasal and Body Inflammation and Airway Sensitivity
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Dust mite extract, Fluticasone, Methacholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Dietary Oxysterols and β-Cell Function Among African Americans
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Plant-based diet with no oxysterols|BEHAVIORAL: Standard ADA Diet (SADA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate Safety & Efficacy of Condroflex in Subjects With OA
Status: UNKNOWN
Conditions: Treatment|Osteoarthritis|Elderly
Interventions: OTHER: condroflex and exercise|OTHER: sugar pill and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Geriatrician Interventions on Chemotherapy Delivery in Vulnerable Elderly Oncology Patients
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer|Bladder Cancer|Gastrointestinal Cancer
Interventions: OTHER: Geriatrician review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diagnostic Value of Diffusion-weighted Magnetic Resonance in High-risk Colorectal and Appendiceal Neoplasms
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Peritoneal Metastases|Appendix Cancer|Appendix Neoplasm|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Whole-body diffusion-weighted magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neonatal Neurobehavioral And Motor Behavior In Ultra Early Physical Therapy Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Neonatal Disease|Parenting|Premature Birth
Interventions: COMBINATION_PRODUCT: ultra early physiotherapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Vocal Rest Versus Vocalization Following Xeomin® Injections in Spasmodic Dysphonia
Status: UNKNOWN
Conditions: Adductor Spasmodic Dysphonia
Interventions: BEHAVIORAL: Vocal rest versus vocalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: tipifarnib|DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose CFZ533 in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: CFZ533|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HYBRID: Hydrogen Breath Test in Lactose Digestion
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: OTHER: Fermented infant milk formula|OTHER: Non-fermented infant milk formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory faCtors AfteR acUte Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: [18F]-GE-180 PET|DIAGNOSTIC_TEST: 3T MRI|DIAGNOSTIC_TEST: immune cell profiling in blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ranolazine When Added to Glimepiride in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ranolazine|DRUG: Placebo|DRUG: Glimepiride|BEHAVIORAL: Diet|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study Assessing GS-7340 in Treatment-Naive Adults With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: GS-7340|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study for Epoetin Alfa (PROCRIT) in Cancer Patients Not Receiving Chemotherapy or Radiation
Status: COMPLETED
Conditions: Anemia|Neoplasms
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-Assisted Hair Implantation Using ARTAS System VS Manual Implantation Technique Hair Restoration Study
Status: UNKNOWN
Conditions: Androgenic Alopecia
Interventions: DEVICE: ARTAS System|OTHER: Manual Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Compared to PET/CT for Staging and Treatment Response in Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DEVICE: magnetic resonance imaging|DEVICE: positron emission tomography/computed tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Thrombolysis in Combination With Endhole Aspiration in the Treatment of Acute DVT
Status: COMPLETED
Conditions: Acute Deep Vein Thrombosis
Interventions: DEVICE: Thrombolysis in combination with endhole aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Cryolipolysis on the Fat of Thigh in Korean Women
Status: COMPLETED
Conditions: Lipolysis|Cryotherapy Effect
Interventions: DEVICE: zeltiq|DEVICE: electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transarterial Coil Embolization of the Superior Rectal Arteries for Treatment of Stage II Hemorrhoids
Status: UNKNOWN
Conditions: Hemorrhoids|Embolization, Therapeutic
Interventions: PROCEDURE: Transarterial coil embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People
Status: COMPLETED
Conditions: Lyme Disease
Interventions: BIOLOGICAL: 2217LS|OTHER: 0.9% Sodium Chloride (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER