pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endovascular Exclusion of Thoracoabdominal and/or Paravisceral Abdominal Aortic Aneurysm
Status: RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm|Paravisceral Abdominal Aortic Aneurysm
Interventions: DEVICE: Endovascular Branched Stent-Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing Robotically-Assisted vs. Manually-Executed Total Knee Arthroplasties
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: PROCEDURE: Total Knee Robotically-Assisted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Polyphenol Containing Antioxidants on Oxidative Stress in Diabetic Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: PomGT (500 mg pomegranate extracts, 300 mg green tea and 60mg vitamin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept: A Pilot, Randomized, Double-Blind Study of Oseltamivir Versus Placebo for Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reinforcement of Upper Airway Muscles in Patients With OSAS
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: IOPI|DEVICE: EMT threshold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of Electroacupuncture on Facial Thermal Characteristics of Major Depressive Disorder Patients Based on Infrared Thermal Imaging Technology
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder|Infrared Thermography
Interventions: OTHER: infrared thermography (IRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in the Lung Clearance Index in Pediatric Patients With Asthma
Status: UNKNOWN
Conditions: Childhood Asthma
Interventions: DRUG: Inhaled Fluticasone 50 mcg/twice day|DRUG: Inhaled Fluticasone 100 mcg/twice day|DRUG: Inhaled Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Propranolol|DRUG: Placebo|DEVICE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of BOTOX in Adults With Moderate COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: OnabotulinumtoxinA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Intervention for Skin Self-Examination in Participants With Increased Risk for Melanoma
Status: COMPLETED
Conditions: Dysplastic Nevus|Health Status Unknown|Melanoma|No Evidence of Disease
Interventions: OTHER: Best Practice|BEHAVIORAL: mySmartCheck|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Chemotherapy Effect
Interventions: RADIATION: Chemoradiation|DRUG: FOLFOXIRI Protocol|DRUG: Folfox Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma
Status: SUSPENDED
Conditions: Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IIID Melanoma
Interventions: BIOLOGICAL: LN-144|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Fludarabine|BIOLOGICAL: Interleukin-2 (IL-2)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure
Status: UNKNOWN
Conditions: Chronic Anal Fissure
Interventions: DRUG: Botulinum Toxins|PROCEDURE: Posterolateral internal sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonographic Hysterosalpingography: Oil vs Water Based Media (SHOW Trial)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Lipiodol UF|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases
Status: RECRUITING
Conditions: Neural Tube Defects
Interventions: DEVICE: Modified Surgical Instruments/Devices (Sheaths and Irrigator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Nitric Oxide Supplementation Product on Endothelial Dysfunction and Prehypertensive Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: NEO40 Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the PK, Safety and Tolerability of HCP1803.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP1803-3|DRUG: RLD2002|DRUG: HCP1904-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of the Candidate Vaccine MVA-SARS-2-ST Against COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: MVA-SARS-2-ST
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ECG Versus Ultrasound-guided Positioning of the Peripherally Inserted Central Catheter (PICC) Tip
Status: COMPLETED
Conditions: Infection|Cancer|Malnutrition
Interventions: DEVICE: ECG-guided insertion of PICC|DEVICE: ULTRASOUND-guided insertion of PICC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XParTS II: Capecitabine/CDDP(XP) and S-1/CDDP(SP) as the First-line Treatment for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: SP|DRUG: XP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Indocyanine Green in Robotic Prostate Surgeries
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer Adenocarcinoma|Erectile Dysfunction Following Radical Prostatectomy
Interventions: DRUG: using Indocyanine Green|PROCEDURE: Nerve-sparing robot-assisted laparoscopic radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualized Volume of Oral Contrast Agent in CT Enterography
Status: UNKNOWN
Conditions: CTE
Interventions: DRUG: 1500ml of 2.5% mannitol|DRUG: different volume of 2.5% mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial of Gemcitabine/Carboplatin With or Without Iniparib (SAR240550) (a PARP1 Inhibitor) in Subjects With Previously Untreated Stage IV Squamous Non-Small-Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Squamous Cell Lung Cancer
Interventions: DRUG: gemcitabine/carboplatin|DRUG: gemcitabine/carboplatin plus Iniparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Dupilumab in Participants With Severe Atopic Dermatitis (AD) That Are Not Controlled With Oral Cyclosporine A (CSA) or for Those Who Cannot Take Oral CSA Because it is Not Medically Advisable
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Inspiratory to Expiratory Ratios on Respiratory Mechanics and Oxygenation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
Status: COMPLETED
Conditions: General Anesthesia Using Endotracheal Intubation
Interventions: OTHER: prolonged inspiratory to expiratory (I:E) ratio (1:1)|OTHER: conventional I:E ratio (1:2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Vision-Guided Shared Control for Assistive Robotics Manipulators
Status: COMPLETED
Conditions: Spinal Cord Injury/Disorder
Interventions: DEVICE: Compare two control methods for a wheelchair-mounted robotic manipulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Myocardial Sympathetic Denervation in Parkinson's Disease Using [18F]FDOPA
Status: UNKNOWN
Conditions: Parkinson
Interventions: OTHER: [18F]-DOPA|DEVICE: PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Pragmatic Posterior Capsular Stretch and Crossbody Stretch on the Shoulder Mobility
Status: COMPLETED
Conditions: Shoulder Impingement|Shoulder Pain|Adhesive Capsulitis|Rotator Cuff Tears|Posterior Capsule Tear|Glenohumeral Subluxation|Glenohumeral Dysplasia|Acromioclavicular; Sprain (Strain)|Internal Rotation Contracture-shoulder|External Rotation Contracture-Shoulder|Flexion Contracture|Extension Contracture-Shoulder
Interventions: OTHER: pragmatic posterior capsular stretch|OTHER: cross body stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety of RVL-1201 in Treatment of Blepharoptosis
Status: COMPLETED
Conditions: Blepharoptosis
Interventions: DRUG: RVL-1201|OTHER: Vehicle ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supraclavicular Versus Interscalene Block for Shoulder Surgery
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Supraclavicular Block|PROCEDURE: Interscalene Block|DRUG: Bupivacaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma
Status: RECRUITING
Conditions: Refractory Neuroblastoma|Relapsed Neuroblastoma|High-risk Neuroblastoma
Interventions: BIOLOGICAL: GPC2 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Angiography Compared to Maternal Doppler in Screening for Hypertension in Pregnancy
Status: UNKNOWN
Conditions: Pregnancy Induced Hypertension
Interventions: DIAGNOSTIC_TEST: Optical coherence Tomography Angiography, Uterine artry doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Image Quality and Radiation Dose Associated With Cardiac Scans in Modern CT Scanners
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Cardiac CTA on a photon-counting detector CT (PCD-CT)|DIAGNOSTIC_TEST: Cardiac CTA on a regular CT with Energy-Integrating Detector (EID-CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Question Prompt List for Common Hand Conditions
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Trigger Finger|Trigger Thumb|Dupuytren Contracture|Ganglion Cysts
Interventions: OTHER: Question Prompt List|OTHER: 3 questions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Evaluating CMC-544 In B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Inotuzumab ozogamicin [CMC-544]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Recombinant HIV Vaccines in HIV Infected Young Adults on Stable Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rMVA-HIV (env/gag [TBC-M358] + tat/rev/nef-RT [TBC-M335)])|BIOLOGICAL: rFPV-HIV (env/gag [TBC-F357] + tat/rev/nef-RT [TBC-F349])
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Doses of Edoxaban Using Different Tests (Assays) and Clinical Outcomes
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Status: NOT_YET_RECRUITING
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Regeneration using Injectable platelet-rich fibrin|PROCEDURE: Root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Corticosteroids for Post-infectious Cough in Adults
Status: TERMINATED
Conditions: Post-infectious Cough
Interventions: DRUG: PREDNISON Galepharm Tabl. 20 mg|DRUG: placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Multicenter, Open-Label, Long-Term Study of the Safety, Tolerability, and Efficacy of Intravenous Natalizumab in Subjects With Rheumatoid Arthritis Who Have Previously Participated in Study ELN100226-RA201
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants
Status: COMPLETED
Conditions: Hepatitis B|Tetanus|Poliomyelitis|Diphtheria|Haemophilus Influenzae Type b|Acellular Pertussis
Interventions: BIOLOGICAL: Infanrix™ hexa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Latest Imaging SPECT System Evaluation Phase 1
Status: COMPLETED
Conditions: Rheumatic Disease|Neoplasms|Parathyroid Diseases|Pulmonary Embolism|Heart Diseases|Thyroid Diseases|Kidney Diseases|Dementia|Parkinsonian Disorders
Interventions: RADIATION: Scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: How to Bathe a Person With Dementia? A Bathing Intervention Based on Basale Stimulation® for People With Moderate to Severe Dementia
Status: UNKNOWN
Conditions: Patient Engagement|Behavioral Symptoms
Interventions: BEHAVIORAL: Bathing technique based on Basale Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - 202
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: RINCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.
Status: COMPLETED
Conditions: PCO
Interventions: DRUG: OLIVE OIL 5ML/5MG (BD) NUTRITIONAL SACHET 2100MG (BD)|DRUG: Metformin (1000 mg Twice a day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonradiation-to-endoscopist Endoscopic Retrograde Cholangiopancreatography in Patients With Complexity Level I/II
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography , Gallstone
Interventions: RADIATION: nonradiation-to-endoscopist endoscopic retrograde cholangiopancreatography|RADIATION: standard endoscopic retrograde cholangiopancreatography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Uveitis
Interventions: DRUG: Izokibep|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block in the Analgesia of Acute Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute
Interventions: PROCEDURE: TAP block|OTHER: Conventional analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: Avonex (IFNβ-1-a, Biogen Netherlands B.V)|DRUG: Rebif (IFNβ-1-a, Merck Europe B.V.)|DRUG: Extavia (IFNβ-1-b, Novartis Europharm Limited)|DRUG: Betaseron (IFN-β-1-b, BAY86-5046, Bayer AG)|DRUG: Plegridy (Peg IFNβ-1-a, Biogen Netherlands B.V)|DRUG: MS disease modifying drugs (MSDMDs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease
Status: UNKNOWN
Conditions: Cerebral Small Vessel Diseases
Interventions: DRUG: mouse nerve growth factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADSTILADRIN (=INSTILADRIN) in Patients With High-Grade, Bacillus Calmette-Guerin (BCG) Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC)
Status: COMPLETED
Conditions: Superficial Bladder Cancer
Interventions: BIOLOGICAL: ADSTILADRIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Evaluation of a RCMP to Predict Failure of Maxillomandibular Advancement Surgery for OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Maxillomandibular Advancement Surgery
Interventions: DEVICE: RCMP titration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of Abraxane in Combination With Carboplatin to Treat Advanced NSCL Cancer in the Elderly
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Carcinoma|Squamous Cell Carcinoma|Adenocarcinoma|Carcinoma, Large Cell|Lung Neoplasm
Interventions: DRUG: nab-paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of a Mixed Compound of Antioxidants in Terms of Endothelium Damage/Function in Pediatric Subjects With Obesity.
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: DIETARY_SUPPLEMENT: Auxilie® Immuplus, Envicon Medical, Verona, Italy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Ranging Study of Dialysate Containing Soluble Iron to Treat Subjects With End Stage Renal Disease (ESRD) Receiving Chronic Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease (ESRD)
Interventions: DEVICE: Standard Bicarbonate Solution|DRUG: Soluble Ferric Pyrophosphate|DRUG: Soluble Ferric Pyrophosphate|DRUG: Soluble Ferric Pyrophosphate|DRUG: Soluble Ferric Pyrophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Antibiotic Use in Neonatal Intensive Care Units in China
Status: RECRUITING
Conditions: Neonates
Interventions: BEHAVIORAL: Collaborative Antimicrobial Stewardship Program (ASP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia|Coronary Artery Disease
Interventions: DRUG: mipomersen sodium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Corticosteroids Avoidance Study in Severe Asthma Patients
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Placebo once daily|DRUG: QAW039 150 mg once daily|DRUG: QAW039 450 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Lithium Carbonate 400 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 24hr Effects of Tiotropium Bromide in Tetraplegia
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Tiotropium Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Berry Oil Cream on Atopic Eczema and Skin
Status: TERMINATED
Conditions: Atopic Dermatitis Eczema
Interventions: DEVICE: Berry Oil Cream|OTHER: Reference Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
Status: COMPLETED
Conditions: Trachoma|Chlamydia Trachomatis
Interventions: DRUG: Azithromcyin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SPIDER: A Research & QI Collaboration Supporting Practices in Improving Care for Complex Elderly Patients
Status: ENROLLING_BY_INVITATION
Conditions: Polypharmacy|Inappropriate Prescribing|Aged|Primary Health Care|Quality Improvement|Electronic Health Records
Interventions: PROCEDURE: SPIDER|PROCEDURE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps
Status: COMPLETED
Conditions: Chronic Sinusitis|Nasal Polyposis
Interventions: DRUG: S8 Sinus Implant|DRUG: Mometasone furoate nasal spray|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Furmonertinib in Patients With Epidermal Growth Factor Receptor 20ins Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Exon 20 Insertion Mutation
Interventions: DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans
Status: RECRUITING
Conditions: Barrett Esophagus|GERD|Obesity|Esophageal Cancer
Interventions: DIAGNOSTIC_TEST: Esocheck/Esoguard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB094 in Adults With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIIB094|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Gemtuzumab Ozogamicin|DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR T-cells Against CD30 (HSP-CAR30) for Relapsed/ Refractory Hodgkin and T-cell Lymphoma.
Status: UNKNOWN
Conditions: Hodgkin Lymphoma, Adult|T Cell Lymphoma
Interventions: BIOLOGICAL: HSP-CAR30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dulaglutide|DRUG: Placebo|DRUG: SGLT2 inhibitor|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Assess the Safety, Tolerability and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease and Persistent Motor-Complications Despite Optimized Treatment With Available Anti-Parkinsonian Medications
Status: COMPLETED
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: ABT-SLV187
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: idarubicin|DRUG: mesna|DRUG: mitoxantrone hydrochloride|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study
Status: COMPLETED
Conditions: Idiopathic Growth Hormone Deficiency|Turner Syndrome
Interventions: OTHER: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Phase II/III Study of AZD2816, for the Prevention of COVID-19 in Adults
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2
Interventions: BIOLOGICAL: AZD1222|BIOLOGICAL: AZD2816
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Interleukin-1 in Postprandial Fatigue - The Cheesecake Study
Status: COMPLETED
Conditions: Postprandial Fatigue
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: An Exploratory Study of RGT Strategy on Optimal NUC-experienced Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon alfa-2a plus Entecavir|DRUG: Peginterferon alfa-2a plus Lamivudine|DRUG: Peginterferon alfa-2a plus Adefovir|DRUG: Peginterferon alfa-2a plus Tenofovir|DRUG: Entecavir|DRUG: Lamivudine|DRUG: Adefovir|DRUG: Tenofovir disoproxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers
Status: COMPLETED
Conditions: Advanced Rectal Cancers
Interventions: RADIATION: Preoperative chemo-radiation with IG-IMRT dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Synergistic Effects of a Cranberry Beverage on Cognitive Function
Status: COMPLETED
Conditions: Attention|Mood
Interventions: DIETARY_SUPPLEMENT: Cranberry Juice Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Cusatuzumab Plus Azacitidine in Japanese Participants With Newly Diagnosed Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome Who Are Not Candidates for Intensive Treatment
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cusatuzumab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mediastinoscopy-assisted Transhiatal Esophagectomy Versus Thoraco-laparoscopic Esophagectomy for Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: PROCEDURE: Thoraco-laparoscopic esophagectomy|PROCEDURE: Mediastinoscopy-assisted transhiatal esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Cognitive Flexibility in Mindfulness Intervention: a Functional Near-infrared Spectroscopy Study
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delivery of Self Training and Education for Stressful Situations-Telephone Version
Status: UNKNOWN
Conditions: PTSD
Interventions: BEHAVIORAL: DESTRESS-T|OTHER: Optimized Usual Care (OUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cancer
Interventions: DRUG: AMG 386|DRUG: AMG 386 Placebo|DRUG: Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Insertional Achilles Tendinopathy Effectiveness
Status: COMPLETED
Conditions: Insertional Achilles Tendinopathy
Interventions: OTHER: Acupuncture and Home Exercise|OTHER: Home Exercise Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An 8 Week Study Looking At The Efficacy, Toleration And Safety Of SS-RBX For Stress Urinary Incontinence.
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: DRUG: SS-RBX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Register of Treatment of Unprotected Left Main Coronary Artery Stenosis in Andalucía
Status: UNKNOWN
Conditions: Unprotected Left Main Coronary Artery Stenosis
Interventions: PROCEDURE: Coronary stent procedure (CSP)|PROCEDURE: Coronary-artery bypass grafting (CABG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye
Status: NOT_YET_RECRUITING
Conditions: Dry Eye
Interventions: DRUG: 3% Diquafosol tetrasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of pRehospital Intervention With trAditional Chinese Medicine for Acute strokE
Status: UNKNOWN
Conditions: Stroke|Acute Ischemic Stroke|Acute Intracranial Hemorrhage
Interventions: DRUG: Xingnaojing injection within 24 hours of symptom onset
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Vagus Nerve Pulmonary Branch Block on Postoperative Cough After VATS Lung Resection
Status: RECRUITING
Conditions: Postoperative Cough|Thoracoscopy|Pulmonary Resection|Vagus|Nerve Block
Interventions: PROCEDURE: Vagus Nerve Pulmonary Branch Block|PROCEDURE: Vagus Nerve Pulmonary Branch Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T-cell Infusion Following Peripheral Blood Stem Cell Transplant in Treating Patients With Recurrent or High-Risk Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Grade III Lymphomatoid Granulomatosis|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Post-transplant Lymphoproliferative Disorder|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells|PROCEDURE: autologous hematopoietic stem cell transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical Trial
Status: RECRUITING
Conditions: Healthy Volunteer
Interventions: DIETARY_SUPPLEMENT: Urolithin A|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cocogen Trial: COoled Versus COnventional Radiofrequency Treatment of the GENicular Nerves for Chronic Knee Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Cooled radiofrequent treatment|DEVICE: Conventional radiofrequent treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy of Dietary Ingredient in Vitality and Metabolic Factors in Healthy Individuals
Status: RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Dolichos biflorus (Horsegram) seed extract|DIETARY_SUPPLEMENT: Carica papaya leaves extract|DIETARY_SUPPLEMENT: Placebo (MCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Feasibility and Accuracy of Hybrid Magnetic Resonance and Positron Emission Tomography With 18F-Fluorodeoxyglucose in Diagnosing Cardiac Sarcoidosis
Status: TERMINATED
Conditions: Cardiac Sarcoidosis
Interventions: DIAGNOSTIC_TEST: hybrid PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comprehensive Fall Prevention System for Memory Care: Final Feasibility and Randomized Controlled Study
Status: UNKNOWN
Conditions: Dementia
Interventions: DEVICE: SafelyYou|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interventional Study of Effects on Spine Height With Two Unloading Positions
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: aquatic vertical suspension.|OTHER: land-based supine flexion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Session Computerized Mental Health Intervention for Rural Indian Adolescents
Status: WITHDRAWN
Conditions: Well-Being|Depression|Anxiety
Interventions: BEHAVIORAL: Growth, Gratitude, & Positive Activities|BEHAVIORAL: Study Skills Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides
Status: UNKNOWN
Conditions: Mycosis Fungoides|Cutaneous T-cell Lymphoma
Interventions: RADIATION: Total skin electron beam therapy (TSEBT)|DRUG: mechlorethamine gel 0.016%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DBT Skills Plus EMDR for BPD and Trauma
Status: RECRUITING
Conditions: Borderline Personality Disorder|Trauma
Interventions: BEHAVIORAL: Dialectical Behavioral Therapy Skills Training|BEHAVIORAL: EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Cisplatin, and Cetuximab (TPC) in Palliative Treatment of Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Cetuximab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety and Effectiveness of Golimumab in Patients With Severe, Persistent Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: BIOLOGICAL: CNTO 148 / Golimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Minimally Invasive Robotic Spine Surgery
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: Renaissance, Mazor Robotics Ltd, Caesare, Israel|PROCEDURE: free hand technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gait Analysis in Patients With Hemiplegia Using Insole Splint.
Status: RECRUITING
Conditions: Gait, Hemiplegic|Splints|EMG
Interventions: DEVICE: Insole Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Measuring Patient Satisfaction With Facial Appearance: Development and Validation of a New Patient-Reported Outcome Measure
Status: COMPLETED
Conditions: Head and Neck Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Relacorilant in Combination With Nab-Paclitaxel in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Relacorilant, 100 mg and 25 mg|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their Partners
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregiver|Glioma
Interventions: OTHER: Best Practice|OTHER: Informational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Esophageal Motility in Eosinophilic Esophagitis Evaluated by High Resolution Manometry.
Status: UNKNOWN
Conditions: Eosinophilic Esophagitis
Interventions: DEVICE: High resolution manometry (HRM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217)
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of a Neoadjuvant Combination: "Chemotherapy-targeted Therapy" in Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cetuximab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Peripheral Blood Mononucleated Cells for Treatment of Liver Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DRUG: G-colony stimulating factor|OTHER: Infusion of the mobilized monocyte cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Minilaparotomy Provided by Trained Clinical Officers and Assistant Medical Officers: a Non-inferiority Trial
Status: COMPLETED
Conditions: Sterilization, Tubal
Interventions: PROCEDURE: tubal ligation by minilaparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Immediate Versus Delayed Tracheal Extubation on Length of ICU Stay of Cardiac Surgical Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Ultra Fast-Track Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy
Status: COMPLETED
Conditions: Breast Implant Infection|Mammoplasty
Interventions: OTHER: Normal saline|DRUG: Cefazolin|PROCEDURE: Skin biopsy|PROCEDURE: Bilateral skin- or nipple-sparing mastectomies|DEVICE: Tissue expander|DEVICE: Breast implant|PROCEDURE: Autologous flap|OTHER: Acellular dermal matrix sling|DRUG: Gentamicin|DRUG: Bacitracin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain
Status: UNKNOWN
Conditions: Lung Neoplasms|Lung Cancer|Pulmonary Neoplasm|Postoperative Pain|Thoracoscopic Surgery
Interventions: PROCEDURE: muscle layer fixation of thoracic drainage tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT