pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|High Risk Myelodysplastic Syndrome|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm|Myeloproliferative Neoplasm|Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Myelodysplastic Syndrome|Recurrent Myelodysplastic/Myeloproliferative Neoplasm|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome|Very High Risk Myelodysplastic Syndrome
Interventions: DRUG: Edetate Calcium Disodium|DIETARY_SUPPLEMENT: Multivitamin|DRUG: Succimer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin on Cognitive Function in Patients Diagnosed With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DRUG: melatonin|DRUG: placebo like melatonin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Adult Subjects
Interventions: DRUG: ID110521156|DRUG: Placebo of ID110521156
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of PET Probe [64]Cu-Macrin in Cardiovascular Disease, Cancer and Sarcoidosis.
Status: UNKNOWN
Conditions: Sarcoid|Cardiovascular Diseases|Cancer
Interventions: DRUG: [64]Cu Macrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ginger on Nausea and Vomiting During Acute Gastroenteritis in Children
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DIETARY_SUPPLEMENT: Ginger|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma|Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma|Recurrent Childhood Central Nervous System Neoplasm|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Neuroblastoma|Refractory Malignant Solid Neoplasm|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Primary Central Nervous System Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Selumetinib|DRUG: Selumetinib Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI)
Status: UNKNOWN
Conditions: Stable Angina|Percutaneous Coronary Intervention
Interventions: DRUG: Adenosin|OTHER: placebo|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Oxybutynin (Oxytrol, BAY839380)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ibrutinib in the Treatment of Chronic Lymphocytic Leukemia and Mantle-cell Lymphoma in Routine Clinical Practice
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Mantle-Cell
Interventions: DRUG: Ibrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laryngoscope Versus CMAC for Endotracheal Intubation in Patients Undergoing Emergent Airway Management
Status: COMPLETED
Conditions: Acute Respiratory Distress
Interventions: PROCEDURE: CMAC videolaryngoscope|PROCEDURE: Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Clopidogrel for Cerebral Infarction Treatment
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: clopidogrel (SR25990C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Classroom Study to Assess Efficacy and Safety of MTS in Pediatric Patients Aged 6-12 With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Plasma Procalcitonin in Prediction of Intra-amniotic Infection in Preterm Premature Rupture of Membrane
Status: UNKNOWN
Conditions: Intra-amniotic Subclinical Infection.
Interventions: DRUG: procalcitonin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms of the Relaxation Response in Elderly Hypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Stress Management Training|BEHAVIORAL: Stress Management Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pudendal Nerve Block for Post-Episiotomy Pain Relief
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Pudendal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of FCM vs Standard of Care in Treating Iron Deficiency Anemia in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Ferric Carboxymaltose|DRUG: Standard Medical Care (SMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tobacco Flavoring and Liquid Composition on Vaping Topography
Status: RECRUITING
Conditions: Tobacco-Related Carcinoma
Interventions: OTHER: Vaping|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients.
Status: COMPLETED
Conditions: Hip Fractures|Anesthesia|Hypotension Drug-Induced|Cardiac Output, Low
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Pulpotomy in Carious First Permanent Molar
Status: NOT_YET_RECRUITING
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: Vital Pulp Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAXUS ARRIVE: TAXUS Peri-Approval Registry: A Multi-Center Safety Surveillance Program
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Express 2™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide in Patients With Recurrent and Refractory Diffuse Large b
Status: ENROLLING_BY_INVITATION
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Chidamide|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Fecal Microbiome Transplantation in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Administration of donor FMT|OTHER: Administration of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of NN1250 With Insulin Glargine in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)
Status: COMPLETED
Conditions: Pancreatic Insufficiency|Cystic Fibrosis
Interventions: DRUG: Omeprazole 20mg Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)
Status: COMPLETED
Conditions: Skin Aging
Interventions: BIOLOGICAL: Human platelet extract (cosmetic product)|OTHER: Vanicream Gentle Facial Cleanser|OTHER: EltaMD UV Daily Broad-Spectrum SPF 40|OTHER: EltaMD PM Therapy Facial Moisturizer|OTHER: Vanicream Lite Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Usefulness of Lidocaine as Topical Pharyngeal Anaesthesia in Esophagogastroduodenoscopy Under Sedation With Propofol
Status: COMPLETED
Conditions: Esophagogastroduodenoscopy
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Game Based Approach on Oxygenation, Functional Capacity and Quality of Life in Primary Ciliary Dyskinesia
Status: COMPLETED
Conditions: Primary Ciliary Dyskinesia|Kartagener Syndrome|Immotile Cilia Syndrome
Interventions: OTHER: Home based therapy|OTHER: Game and home based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fondaparinux to Prevent Thrombotic Complications and Graft Failure in Patients Undergoing Coronary Artery Bypass Graft Surgery: The Fonda CABG Study
Status: UNKNOWN
Conditions: Coronary Bypass Graft Failure/Occlusion
Interventions: DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) in Combination With Weekly Docetaxel in Participants With Stage IV Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Ramucirumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: Ecopipam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Working With Community Health Workers to Increase ORS Use in Uganda
Status: COMPLETED
Conditions: Infantile Diarrhea|Diarrhea|Dehydration
Interventions: BEHAVIORAL: Free Distribution|BEHAVIORAL: Preemptive Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Kinesiology Taping on Lumbar Region Structures and Balance in Transfemoral Amputees
Status: COMPLETED
Conditions: Transfemoral Amputees|Kinesiology Taping
Interventions: OTHER: Kinesiology taping|OTHER: Six minutes walking test|OTHER: Shame Kinesiology Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Social Support During In Vivo Exposure for PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Anxiety Disorders|Mental Disorder|Traumatic Disorder
Interventions: BEHAVIORAL: Prolonged Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Fidelity Simulation Training: A Mixed Method Study
Status: COMPLETED
Conditions: Simulation of Physical Illness|Satisfaction
Interventions: DEVICE: High-Fidelity Simulation Manikin|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Citric Flavonoid on Endothelial Function
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Capsule containing citrus flavonoid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Plasma Gel Injection Versus Polydioxanone Cog Threads Insertion for the Treatment of Atrophic Post-acne Scars: a Split-face
Status: COMPLETED
Conditions: Acne Vulgaris|Atrophic Acne Scar
Interventions: PROCEDURE: Subcision plus Plasma gel injection Vs Subcision plus Cog PDO threads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DNA in Blood Samples From Patients With Neuroblastoma
Status: COMPLETED
Conditions: Disseminated Neuroblastoma|Localized Resectable Neuroblastoma|Localized Unresectable Neuroblastoma|Recurrent Neuroblastoma|Regional Neuroblastoma|Stage 4S Neuroblastoma
Interventions: OTHER: laboratory biomarker analysis|GENETIC: polymerase chain reaction|GENETIC: polyacrylamide gel electrophoresis|GENETIC: DNA analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigating Brown Adipose Tissue Activation in Humans
Status: COMPLETED
Conditions: Metabolic Diseases
Interventions: OTHER: Period 1 Visit 1 - Cold PET-CT Vehicle, Visit 2 -Warm PET-CT Vehicle|DRUG: Period 1 Visit 1 - Cold PET-CT Vehicle, Visit 2 -Warm PET-CT Glucagon|OTHER: Period 1 Visit 1 - Cold PET-CT Vehicle, no visit 2 as BAT negative|DRUG: Period 2 - Visit 1 Warm Control vehicle, Visit 2 Warm Glucagon, Visit 3 Cold control|DRUG: Period 2 - Visit 1 Warm Glucagon, Visit 2 Cold control , Visit 3 Warm control|DRUG: Period 2 -Visit 1 cold control, Visit 2 warm control, Visit 3 Warm glucagon|DRUG: Period 2 -Visit 1 cold control, visit 2 warm glucagon, visit 3 warm control|DRUG: Period 2- Visit 1 Warm glucagon, visit 2 warm control, visit 3 cold control|DRUG: Period 2 - Visit 1 Warm control, visit 2 cold control, visit 3 warm glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Sulforaphane in Patients With Prodromal to Mild Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: sulforaphane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Complete and Accurate Statistical Data of 60 Patients|CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately|Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients|According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted|Scientific and Rigorous Statistical Analysis of Data
Interventions: OTHER: CYP3A5*1*、CYP3A5*1*3|OTHER: CYP3A5*3*3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injury|Spinal Cord Injury at C5-C7 Level|SCI - Spinal Cord Injury|Upper Extremity Paralysis|Upper Extremity Dysfunction|Tetraplegia|Upper Extremity Paresis|Cervical Spinal Cord Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK), and Food Effect of MK-7762 in Healthy Adults
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: MK-7762 (TBD09)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Left Subclavian Regurgitation Evaluated by Ultrasound Doppler and 4D Flow MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Regurgitation
Interventions: DIAGNOSTIC_TEST: transthoracic echocardiography|DIAGNOSTIC_TEST: Cardiovascular Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate Patients With Acromegaly Treated With Lanreotide Autogel (Somatuline ATG)
Status: WITHDRAWN
Conditions: Acromegaly
Interventions: DRUG: lanreotide (Autogel formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Programmed Intermittent Epidural Bolus With Continuous Epidural Infusion for Labor Epidural Analgesia
Status: UNKNOWN
Conditions: Labor Analgesia
Interventions: PROCEDURE: Epidural analgesia|PROCEDURE: Continuous epidural infusion|PROCEDURE: Intermittent epidural bolus|DRUG: ropivacaine|DRUG: sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simulation Applications on the Level of Pressure Injury Knowledge and Evaluation
Status: NOT_YET_RECRUITING
Conditions: Pressure Injury
Interventions: OTHER: Pressure injury training|OTHER: Simulated Manneqquin training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D Supplementation to Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Cholecalciferol (vitamin D)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nodular Shrinking in Dupuytren Disease
Status: RECRUITING
Conditions: Dupuytren's Disease
Interventions: DRUG: Vitamin E-creme (Remederm®) vs Vaseline (Placebo)|PROCEDURE: Ultrasound measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Disorder of Lipid Storage and Metabolism|Lipid Metabolism Disorders|Metabolic Disorder
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy
Status: COMPLETED
Conditions: Age-Related Maculopathy|Age-Related Maculopathies|Eye Diseases|Retinal Degeneration|Macular Degeneration
Interventions: BIOLOGICAL: RN6G|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant/Adjuvant Cadonilimab Plus Chemotherapy in Patients With Resectable PD-L1 Negative NSCLC
Status: NOT_YET_RECRUITING
Conditions: NSCLC
Interventions: DRUG: cadonilimab+paclitaxel+carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva
Status: RECRUITING
Conditions: Fibrodysplasia Ossificans Progressiva (FOP)
Interventions: DRUG: INCB000928|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut Origin
Status: COMPLETED
Conditions: Advanced Digestive System Neuroendocrine Neoplasm|Duodenal Neuroendocrine Tumor G1|Functional Pancreatic Neuroendocrine Tumor|Gastric Neuroendocrine Tumor|Intermediate Grade Lung Neuroendocrine Neoplasm|Low Grade Lung Neuroendocrine Neoplasm|Nonfunctional Pancreatic Neuroendocrine Tumor|Thymus Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation
Status: COMPLETED
Conditions: Vitamin B 12 Deficiency
Interventions: DIETARY_SUPPLEMENT: Vit B12|DIETARY_SUPPLEMENT: Vit B12|DIETARY_SUPPLEMENT: Vit B12|DIETARY_SUPPLEMENT: Vit B12|DIETARY_SUPPLEMENT: Vit B12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Auricular Neuromodulation in Veterans With Fibromyalgia
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: Percutaneous electrical nerve field stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Indoor Pollutants on House Dust Mite Allergic Asthma
Status: WITHDRAWN
Conditions: Allergic Asthma|Allergy to House Dust Mite
Interventions: OTHER: Formaldehyde and NO2 (Exposure to indoor pollutants)|OTHER: Placebo (Exposure to indoor pollutants)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Comparison of the Clinical Efficacy Between I-gel and LMA-Supreme, the Two Most Recently Developed Supraglottic Airway Devices, in Elderly Patients
Status: COMPLETED
Conditions: The Elderly Patients Aged Between 65 and 85
Interventions: DEVICE: I-gel|DEVICE: Supreme-LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Electrical Stimulation for the Treatment of Glaucoma
Status: RECRUITING
Conditions: Glaucoma|Glaucoma, Open-Angle
Interventions: DEVICE: Repetitive, Transorbital Alternating Current Stimulation (rtACS)|DEVICE: Sham Repetitive, Transorbital Alternating Current Stimulation (rtACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DCB Versus Primary Selective Stenting in TASC C/D Femoropopliteal Artery Disease
Status: RECRUITING
Conditions: Safety Issues|Efficacy, Self
Interventions: DEVICE: paclitaxel-coated balloon angioplasty or bare mental stents implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Rhubarb Extract on Stool Frequency and Biological Markers of Intestinal Function in Seniors With Low Defecation
Status: COMPLETED
Conditions: Constipation - Functional
Interventions: DIETARY_SUPPLEMENT: single dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract|DIETARY_SUPPLEMENT: placebo coated tablet|DIETARY_SUPPLEMENT: double dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine, in High Risk Pregnant Women Aged 15 to 49 Years and Infants Born to the Vaccinated Mothers
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV MAT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare TWA Test and EPS Test for Predicting Patients at Risk for Life-threatening Heart Rhythms (ABCD Study)
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy|LV Dysfunction
Interventions: DEVICE: T-Wave Alternans test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brain Training in Preterm Children at Risk for Inattention, Hyperactivity, and Executive Function Impairment
Status: COMPLETED
Conditions: Premature Birth
Interventions: BEHAVIORAL: Brain Training (Active)|BEHAVIORAL: Brain Training (Passive)|BEHAVIORAL: Brain Training (Active or Passive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applying the Spanish Version of the UP-A as a Universal School-based Anxiety and Depression Prevention Program
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: UP-A adapted as a preventive intervention|BEHAVIORAL: Same than experimental group (EG), after EG finishes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Menorrhagia Study in Women With Treatment-resistant Menorrhagia
Status: COMPLETED
Conditions: Menorrhagia
Interventions: DRUG: Asoprisnil (BAY86-5294)|DRUG: Asoprisnil (BAY86-5294)|DRUG: Asoprisnil (BAY86-5294)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microarray Analysis of Scalp Biopsies After Minoxidil Treatment
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: OTHER: Minoxidil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Azilsartan on Aldosterone in Postmenopausal Females
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoximil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Brain|Metastatic Solid Neoplasm|Recurrent Colorectal Carcinoma|Recurrent Pancreatic Carcinoma|Recurrent Solid Neoplasm|Stage IV Colorectal Cancer|Stage IV Pancreatic Cancer|Stage IVA Colorectal Cancer|Stage IVA Pancreatic Cancer|Stage IVB Colorectal Cancer|Stage IVB Pancreatic Cancer|Unresectable Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: siRNA-transfected Peripheral Blood Mononuclear Cells APN401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection of Pioglitazone in Acute Ischemic Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 Antibody Combined With Anlotinib in the Treatment of Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DRUG: anlotinib and anti PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection
Status: WITHDRAWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Imdusiran|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms
Status: NOT_YET_RECRUITING
Conditions: Premenstrual Dysphoric Disorder|Premenstrual Exacerbation of Mood Disorder
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiation Therapy Plus Paclitaxel in Treating Patients With Nonmetastatic, Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The eCALM Study - An Online Mindfulness-Based Stress Reduction Program for Individuals Living With Cancer in Alberta
Status: UNKNOWN
Conditions: Mindfulness-Based Stress Reduction (MBSR)|Cancer
Interventions: OTHER: Immediate MBSR|OTHER: Wait-list Control Group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single-And Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of WD-890 Tablets in Healthy Chinese Subjects
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: WD-890|DRUG: WD-890 Tablets Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The ESTxENDS Trial- Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation-extension of Follow-up
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: OTHER: ENDS (vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RENEWING HEALTH - RegioNs of Europe WorkINg Together for HEALTH
Status: COMPLETED
Conditions: Type 2 Diabetes|Coronary Artery Disease|Heart Failure|Atrial Fibrillation|Other Arrhythmias
Interventions: BEHAVIORAL: Health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Application of Robot-assisted Laparoscopic Pathways in Radical Cystectomy
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: PROCEDURE: robit-assist extraperitoneal laparoscopic radical cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Hydrocodone/Acetaminophen Extended Release|DRUG: Hydrocodone/Acetaminophen Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Yoga on Nurses' Perceived Stress Burnout and Life Satisfaction During the Pandemic Period
Status: COMPLETED
Conditions: Abdominal Surgery|Hypertension|Done Laughter Yoga Before|Epilepsy
Interventions: OTHER: Laughter yoga practiced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Botulinum Toxin Type A for Moderate to Severe Crow's Feet Lines
Status: COMPLETED
Conditions: Skin Aging
Interventions: DRUG: Placebo|DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Neuroimaging in the Selection of Acute Ischemic Stroke (AIS) Patients to Endovascular Treatment (EVT)
Status: COMPLETED
Conditions: Ischemic Stroke|Arterial Occlusion|CTS|Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: MULTIMODAL MAGNETIC RESONANCE (Multimodal MR)|DIAGNOSTIC_TEST: MULTIMODAL COMPUTERIZED TOMOGRAPHY (Multimodal CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Heart Disease|Hopelessness|Physical Activity|Motivation|Social Support|Covid19
Interventions: BEHAVIORAL: Motivational social support from nurse|BEHAVIORAL: Motivational social support from nurse with additional support from significant other|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: follow-up coronary angiography|PROCEDURE: Clinical follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis
Status: UNKNOWN
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate Picato® and MAL PDT day 1, day 5|DRUG: Ingenol mebutate Picato® day 2, 3, 4|PROCEDURE: MAL PDT day 5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients
Status: COMPLETED
Conditions: Pain, Chronic
Interventions: BEHAVIORAL: Daily Self-Monitoring Surveys + Contingency Management|BEHAVIORAL: Daily Self-Monitoring Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Treatment for PTSD and MDD in TBI
Status: NOT_YET_RECRUITING
Conditions: PTSD, Post Traumatic Stress Disorder|Major Depressive Disorder|Traumatic Brain Injury
Interventions: DRUG: IV ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitazoxanide and Lansoprazole Based Regimens for H. Pylori Management
Status: UNKNOWN
Conditions: Helicobacter Pylori
Interventions: DRUG: Naïve patients - ACO therapy|DRUG: Naïve patients - LNDL therapy|DRUG: Naïve patients - MNDL therapy|DRUG: Treatment-experienced patients- LNDL therapy|DRUG: Treatment-experienced patients- MNDL therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) on RAdiographic Damage in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: diclophenac|DRUG: diclophenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Risedronate for Patients With Peripheral Lung Tumors Treated With SBRT
Status: COMPLETED
Conditions: Lung Neoplasm
Interventions: DRUG: risedronate|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma
Status: COMPLETED
Conditions: Granulocytic Sarcoma|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: 6,8-Bis(benzylthio)octanoic Acid|DRUG: Cytarabine|PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Mitoxantrone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary Syndrome
Status: RECRUITING
Conditions: Myocardial Infarction|Acute Coronary Syndrome
Interventions: DRUG: Low-dose aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing BREASTChoice Into Practice
Status: COMPLETED
Conditions: Breast Reconstruction|Breast Cancer
Interventions: OTHER: Breast Reconstruction Education and Support Tool (BREASTChoice)|OTHER: Attention Control Website|OTHER: Clinician Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Nicardipine on Renal Function in Deliberate Hypotension
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: DRUG: Nicardipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Test the Efficacy and Safety of Vafidemstat in Adult Borderline Personality Disorder Population
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: vafidemstat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Misoprostol in Reducing Post Partum Hemorrhage After Labor Induction by Oxytocin
Status: COMPLETED
Conditions: Prevention of Post Partum Hemorrhage After Labor Induction
Interventions: DRUG: Misoprostol after delivery|DRUG: Oxytocin after delivery|DRUG: Oxytocin before delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of LJP 394 (Abetimus Sodium) in Lupus Patients
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: abetimus sodium (LJP 394)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydroxyurea Optimization Through Precision Study
Status: RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Anemia
Interventions: DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lactoferrin in Covid-19 Hospitalized Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Bovine lactoferrin|DIETARY_SUPPLEMENT: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rhPro-UK in Acute Ischaemic Stroke Within 4.5 Hours of Stroke Onset Trial 2(PROST-2)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: rhPro-UK|DRUG: rt-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity First-in-human Dose-ranging Study of Self-Amplifying RNA Seasonal Influenza Vaccine in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: ARCT-2138|BIOLOGICAL: Licensed Quadrivalent Vaccine for younger adults|BIOLOGICAL: Licensed Quadrivalent Vaccine for older adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Optimal Dose of Remifentanil During MRI of the Heart Under General Anaesthesia
Status: UNKNOWN
Conditions: Children|Heart Diseases|Anaesthesia|Magnetic Resonance Imaging
Interventions: DRUG: Remifentanil and/or propofol|DRUG: Remifentanil and/or propofol|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8
Interventions: BIOLOGICAL: Nivolumab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin A Supplementation on Intestinal Parasitic Reinfections
Status: COMPLETED
Conditions: Intestinal Parasitic Infections|Malnutrition|Anemia
Interventions: DRUG: vitamin A supplements|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Educational Intervention to Improve Patient-Physician Awareness of Cardiovascular Risk in Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Arthritis, Rheumatoid
Interventions: OTHER: YouTube Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Study to Assess the Safety,Tolerability, and Pharmacokinetics of GS-6615 in Healthy Subjects
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: GS-6615|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled, Dose Exploration Study of CTI-1601 in Adult Subjects With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: BIOLOGICAL: CTI-1601|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAXOMAT ® in the Treatment of Severe Early Onset Intrauterine Growth Retardation on Pre-pubertal Children
Status: COMPLETED
Conditions: Fetal Growth Retardation
Interventions: DRUG: somatropin|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis
Status: TERMINATED
Conditions: Bacterial Vaginosis|Vaginal Infection|Vaginal Diseases
Interventions: DRUG: Dequalinium Chloride|DRUG: Metronidazole Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Urologic Neoplasms|Prostate Cancer|Prostate Cancer Metastatic Disease
Interventions: DRUG: Docetaxel|DRUG: Biosyn|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Integrated Within Physiotherapy for Patients With Complex Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: COMBINATION_PRODUCT: Physiotherapy with integrated Virtual Reality|OTHER: Physiotherapy (usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT