pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: DRUG: Intravenous Nutrition (Vitamins) injection|DRUG: Intravenous Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy
Status: TERMINATED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: DRUG: Sodium chloride tablets|DRUG: Isotonic saline intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients
Status: TERMINATED
Conditions: Low Back Pain, Mechanical|Spinal Stenosis|Nerve Root Disorder|Radiculopathy, Cervical|Benign Hypermobility Syndrome
Interventions: OTHER: Beighton score for hypermobility
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET-CT vs. Integrated MR-PET Scanning of GYN Cancers
Status: UNKNOWN
Conditions: Cervical Cancer|Endometrial Cancer|Ovarian Cancer
Interventions: PROCEDURE: PET-CT|PROCEDURE: MR-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
Status: COMPLETED
Conditions: Pineoblastoma
Interventions: DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Dasatinib|DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Ustekinumab (CNTO 1275) in Participants With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo (CP)|DRUG: Ustekinumab 45 mg (CP)|DRUG: Ustekinumab 90 mg (CP)|DRUG: Placebo A (After CP)|DRUG: Placebo B (After CP)|DRUG: Ustekinumab 45 mg (After CP)|DRUG: Ustekinumab 90 mg (After CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia
Status: RECRUITING
Conditions: Essential Hypertension|Primary Hypercholesterolemia
Interventions: DRUG: Fimasartan|DRUG: Ezetimibe/Atorvastatin|DRUG: Fimasartan Placebo|DRUG: Ezetimibe/Atorvastatin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Recurrence Scoring System for Stratifying Stage III Clear Cell Renal Cell Carcinoma of Receiving Adjuvant Treatment
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Aerosol in a Dental Clinic
Status: RECRUITING
Conditions: Covid19
Interventions: DEVICE: High volume evacuation (HVE)|DEVICE: Extraoral vacuum aspirator (EVA)|DEVICE: External evacuation device (EED)|DRUG: Hydrogen Peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Potential of Vojta's Reflex Locomotion as a Pre/Induction Method for Uterine Activity: a Pilot Study
Status: COMPLETED
Conditions: Induced Vaginal Delivery
Interventions: PROCEDURE: Vojta's Reflex Locomotion|PROCEDURE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Addition of Pembrolizumab to Radium-223 in mCRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Radium-223|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD of ADX-850 in Participants With Hypertension
Status: RECRUITING
Conditions: Hypertension|Hypertension,Essential
Interventions: DRUG: ADX-850|DRUG: Placebo|DRUG: Angiotensin Receptor Blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Dalfampridine 10 MG [Ampyra]|BEHAVIORAL: Physical therapy|OTHER: Dalfampridine plus physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate SSGJ-707 in Advanced Gynecologic Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Advanced/Recurrent Endometrial Cancer and Platinum-resistant Ovarian Cancer
Interventions: DRUG: SSGJ-707|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 89Zr-labeled KN035 PET Imaging in Patients With PD-L1 Positive Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: DRUG: 89Zr-KN035
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of ESPB on Intraoperative Hemodynamics in VATS
Status: COMPLETED
Conditions: Video-Assisted Thoracoscopic Surgery|Erector Spinae Plane Block|Mean Arterial Pressure|Heart Rate
Interventions: PROCEDURE: Preoperative Erector spinae plane block|PROCEDURE: Postperative Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Economic Evaluation of an Education Platform for Patients With End-stage Renal Disease
Status: UNKNOWN
Conditions: End-stage Renal Disease|Dialysis|Kidney Transplantation
Interventions: BEHAVIORAL: app-based therapeutic education|BEHAVIORAL: enhanced app-based therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischemic Conditioning for Treatment of Chronic Wounds
Status: UNKNOWN
Conditions: Leg Ulcer|Varicose Ulcer
Interventions: PROCEDURE: Remote Ischemic Conditioning|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Subjective Ratings of Appetite and Glucoregulation of a Low Calorie Diet Supplemented With a High Viscosity Polysaccharide (PolyGlycopleX - PGX)
Status: COMPLETED
Conditions: Appetite and Hunger, Suppression|Blood Glucose, Postprandial
Interventions: DIETARY_SUPPLEMENT: PolyGlycopleX (PGX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting HPV DNA in Anal and Cervical Cancers
Status: SUSPENDED
Conditions: Cervical Cancer|Anal Cancer|HPV-Related Anal Squamous Cell Carcinoma|HPV-Related Cervical Carcinoma|HPV-Related Carcinoma|Uterine Cervical Cancer
Interventions: RADIATION: Radiation Treatment With or Without Chemotherapy|OTHER: Blood Sample Collection|DIAGNOSTIC_TEST: HPV Genotyping (HPV DNA Test)|DIAGNOSTIC_TEST: Testing Archival Tumor Tissue|OTHER: Physical Exam|DIAGNOSTIC_TEST: Positron Emission Tomography Scan (PET Scan)/ Computed Tomography Scan (CT Scan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epidiolex in Obsessive Compulsive Disorder and Related Disorders
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Trichotillomania (Hair-Pulling Disorder)|Tourette Syndrome|Hoarding Disorder
Interventions: DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Duration of Erection With Vardenafil 10 mg
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of AC607 for the Treatment of Kidney Injury in Cardiac Surgery Subjects
Status: TERMINATED
Conditions: Acute Kidney Injury
Interventions: BIOLOGICAL: AC607|BIOLOGICAL: Vehicle Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: DPP-4 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy|Glucose Intolerance During Pregnancy|Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
Interventions: BEHAVIORAL: NNS Restriction Intervention|BEHAVIORAL: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Balint Group on Burnout and Self-efficacy of Nurse Leaders in China: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Burnout|Self Efficacy
Interventions: OTHER: Balint group activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BOTOX® Treatment in Pediatric Lower Limb Spasticity
Status: COMPLETED
Conditions: Pediatrics|Muscle Spasticity|Cerebral Palsy
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Normal Saline (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intramuscular Sebacoyl Dinalbuphine Ester for Post-Hemorrhoidectomy Pain Management
Status: COMPLETED
Conditions: Analgesia Disorder|Pain
Interventions: DRUG: Sebacoyl Dinalbuphine Ester|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl-sedation for Flexible Bronchoscopy: A Randomized, Single Blind, Controlled Study of Satisfaction and Safety.
Status: UNKNOWN
Conditions: Flexible Bronchoscopy|Sedation|Satisfaction|Safety
Interventions: DRUG: Propofol sedation|DRUG: Midazolam and Fentanyl sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Positive Appraisal Improve Trust Between Patients and Therapists, and Change Treatment Effects
Status: COMPLETED
Conditions: Trust|Low Back Pain
Interventions: BEHAVIORAL: intervention|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate an Influenza Vaccine Candidate
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Vaccine GSK1247446A - 4 different formulations|BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Alemtuzumab|DRUG: Basiliximab|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN)
Status: NOT_YET_RECRUITING
Conditions: Refractory Lupus Nephritis
Interventions: BIOLOGICAL: TAK-007|DRUG: Chemotherapy Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Changes in Hair in Adult Participants Taking Oral Oriahnn Capsules With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)
Status: ENROLLING_BY_INVITATION
Conditions: Uterine Fibroids (UF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Pazopanib Monotherapy After First-line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Asian Women
Status: COMPLETED
Conditions: Neoplasms, Ovarian
Interventions: DRUG: Pazopanib|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once a Day (QD) - Twice a Day (BID) Clinical Trial: Didanosine, Lamivudine and Efavirenz Versus Zidovudine, Lamivudine and Efavirenz in the Starting Treatment of HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: didanosine + lamivudine + efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Macular Thickness After Patterns Scan Laser
Status: TERMINATED
Conditions: Non Proliferative Diabetic Retinopathy|Proliferative Diabetic Retinopathy
Interventions: DEVICE: Panretinal photocoagulation with PASCAL system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS for Fatigue in Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DEVICE: Active Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TAP Block in Cesarean Section Patients
Status: COMPLETED
Conditions: Pain Control
Interventions: PROCEDURE: TAP block using Bupivacaine 0.5%|PROCEDURE: TAP block using Bupivacaine 0.25%|PROCEDURE: TAP block using Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Clinical Activity of Initial Intraperitoneal Catumaxomab Followed by Chemotherapy in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Epithelial Ovarian Cancer
Interventions: DRUG: Catumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Positions in Children After Cardiac Surgery
Status: COMPLETED
Conditions: Infant ALL
Interventions: PROCEDURE: Control group (Supine Position)|PROCEDURE: Experimental Group (Right Lateral position)|PROCEDURE: Experimental Group (Left Lateral position)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bilateral Dispensing Comparison of Comfilcon A Over Senofilcon C Contact Lenses
Status: COMPLETED
Conditions: Astigmatism Bilateral
Interventions: DEVICE: Comfilcon A (test)|DEVICE: Senofilcon C (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs Compared With Telaprevir (a Licensed Product) for Treatment of Chronic Hepatitis C Infection in Treatment-experienced Adults
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/r/ABT-267, ABT-333|DRUG: Ribavirin|DRUG: Pegylated Interferon a-2a (PegINF)|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy Participants
Status: COMPLETED
Conditions: Neurodegenerative Diseases
Interventions: DRUG: ONO-2808|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Early Warning Score (I-EWS)
Status: COMPLETED
Conditions: Early Warning Score|Risk Stratification
Interventions: BEHAVIORAL: I-EWS with incorporated clinical assessment (Trigger Tool)|BEHAVIORAL: Standard EWS - Control (Trigger Tool)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Salpingectomy (Tubectomy) With Delayed Oophorectomy in BRCA1/2 Gene Mutation Carriers
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|Ovarian Cancer
Interventions: PROCEDURE: Salpingectomy with delayed oophorectomy|PROCEDURE: Risk-reducing salpingo-oophorectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS060380 in Healthy and Elevated LDL-C Subjects
Status: NOT_YET_RECRUITING
Conditions: MASH
Interventions: DRUG: CS060380
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Effect of Elevit Pregnancy 2nd & 3rd Trimester (Multi-micronutrients & DHA Supplement) on the Nutritional Status of Pregnant Women During Second and Third Trimester
Status: COMPLETED
Conditions: Healthy Pregnant Women
Interventions: DIETARY_SUPPLEMENT: Elevit Pregnancy 2nd & 3rd Trimester|OTHER: Non-Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Impact of Story Starters on Children's Language Development
Status: COMPLETED
Conditions: Language Development
Interventions: BEHAVIORAL: Story Starters Intervention|BEHAVIORAL: Wait-list Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: OTHER: Regular Coffee|OTHER: Decaffeinated coffee|OTHER: Warm water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: INCB001158|DRUG: Epacadostat|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Umbilical Cord Blood Transfusion for Preterm Neonates
Status: WITHDRAWN
Conditions: Prematurity|Respiratory Distress Syndrome|Anemia of Prematurity|Intraventricular Hemorrhage
Interventions: BIOLOGICAL: Autologous cord blood transfusion for preterm neonates|BIOLOGICAL: Autologous cord blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Staccato Loxapine Single Dose PK
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: inhaled Loxapine 0.625 mg|DRUG: inhaled Loxapine 1.25 mg|DRUG: inhaled Loxapine 2.5 mg|DRUG: inhaled Loxapine 5 mg|DRUG: inhaled Loxapine 10 mg|DRUG: inhaled Placebo (0 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: Plasmodium falciparum malaria parasite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Preventive Therapy of White Spot Lesions Using Different Remineralizing Agents in Children From 3 to 12 Years Old
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: OTHER: FLUORINE VARNISH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults
Status: COMPLETED
Conditions: CHD - Coronary Heart Disease
Interventions: DRUG: Propofol|DRUG: Isoflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AMG 319 in HPV Positive and Negative HNSCC
Status: TERMINATED
Conditions: Human Papillomavirus (HPV)|Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Interventions: DRUG: AMG 319 hydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Lifetech CeraFlex™ Post-Market Surveillance Study
Status: COMPLETED
Conditions: Patent Foramen Ovale|Atrial Septal Defect|Patent Ductus Arteriosus
Interventions: DEVICE: CeraFlex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption, Metabolism and Excretion (AME) Study of [14C]EDP-305 in Healthy Male Subjects
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: EDP-305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy|Asphyxia
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Causes of Preventable and Serious Adverse Drug Reactions Related to the Use of Oral Anticoagulants
Status: COMPLETED
Conditions: Embolism and Thrombosis|Hemorrhage
Interventions: BIOLOGICAL: Blood samples for DOAC measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exactech Shoulder Post Market Clinical Follow-up Study
Status: RECRUITING
Conditions: Osteo Arthritis Shoulders|Osteonecrosis|Rotator Cuff Tears|Rotator Cuff Tear Arthropathy|Ankylosing Spondylitis|Post-traumatic Osteoarthritis|Rheumatoid Arthritis|Fracture|Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study.
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Naltrexone, Baclofen, Placebo and Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Daily Use of Lipikar Balm AP From Birth in Infants at High Risk of Developing Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis|Eczema|Asthma|Food Allergies|Allergic Rhinitis
Interventions: DRUG: Lipikar Balm AP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of ODX (Osteodex) in Metastatic Castration Resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Osteodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MKC1106-MT|BIOLOGICAL: MKC1106-MT|BIOLOGICAL: MKC1106-MT
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Injuries
Interventions: BIOLOGICAL: TPX-114|PROCEDURE: Arthroscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second-Line Docetaxel + ASA404 for Advanced Urothelial Carcinoma
Status: WITHDRAWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: Docetaxel|DRUG: ASA404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemetry for Chest Pain of Low Risk for Acute Coronary Syndrome Pts
Status: WITHDRAWN
Conditions: Chest Pain|Telemetry|Acute Coronary Syndrome|Health Care Resource Utilization
Interventions: OTHER: No Telemetry Monitoring|DEVICE: Telemetry Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head-to-head Comparison of 68Ga-PSMA-11 and 18F-PSMA-1007
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 18F-PSMA-1007|DIAGNOSTIC_TEST: 68Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Stage IB2 Cervical Cancer AJCC v8|Stage II Cervical Cancer AJCC v8|Stage IIA Cervical Cancer AJCC v8|Stage IIA1 Cervical Cancer AJCC v8|Stage IIA2 Cervical Cancer AJCC v8|Stage IIB Cervical Cancer AJCC v8|Stage IIIB Cervical Cancer AJCC v8|Stage IVA Cervical Cancer AJCC v8
Interventions: DRUG: Atezolizumab|RADIATION: Brachytherapy|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MonaLisa Touch Randomized Double-Blind Placebo Controlled Study
Status: COMPLETED
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: MonaLisa Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GC Regimen Chemotherapy Plus CIK Cells for Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Stage IV Nasopharyngeal Carcinoma
Interventions: DRUG: GC chemotherapy plus CIK cells (Gemcitabine, Cisplatin, Autologous CIK cells)|DRUG: GC chemotherapy (Gemcitabine, Cisplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patients
Status: COMPLETED
Conditions: Portal Hypertension|Liver Cirrhosis
Interventions: DRUG: Ifetroban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AbobotulinumtoxinA for the Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: AbobotulinumtoxinA dose level 1 or 2|OTHER: placebo|BIOLOGICAL: AbobotulinumtoxinA dose 3|BIOLOGICAL: AbobotulinumtoxinA dose 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-assessment Tool for Implementing the ESCNH
Status: NOT_YET_RECRUITING
Conditions: Development of a Tool to Assess the Level of Implementing the European Standards of Care for Newborn Health|Testing of the Developed Self-assessment Tool in European Hospitals|Self-Assessment
Interventions: OTHER: Please note that this is an observational study; not applicable
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases (CALiPSO-1)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis
Interventions: BIOLOGICAL: CNTY-101|BIOLOGICAL: IL-2|DRUG: Lymphodepleting Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-Over Study of Subcutaneous Study Drug for the Treatment of Patients With Mild to Moderate Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: PL-3994
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Melphalan and Prednisone Versus High Dose Melphalan in Newly Diagnosed Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma|Newly Diagnosed Patients
Interventions: DRUG: Melphalan|DRUG: Lenalidomide|DRUG: Prednisone|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multiple Dose Study of PF-04447943 in Healthy Elderly Volunteers
Status: TERMINATED
Conditions: Healthy|Elderly
Interventions: DRUG: PF-04447943|DRUG: PF-04447943|DRUG: PF-04447943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Two Different Methods of Collecting Stem Cells For an Autologous Stem Cell Transplant in Treating Patients With Diffuse Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dynamic Radiographs in Determining Fusion Level in Adolescent Idiopathic Scoliosis Correction
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: RADIATION: Flexibility Radiographs (supine, supine side-bend, FB)|RADIATION: Flexibility Radiographs (awake traction)|RADIATION: Flexibility Radiographs (STUGA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect and Safety of Pulsed Field Ablation (PFA) in Patients With Paroxysmal Atrial Fibrillation (PAF)
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Pulsed Field Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afrezza With Basal Combination
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Afrezza (insulin human) Inhalation Powder|BIOLOGICAL: insulin degludec|DEVICE: Continuous Subcutaneous Insulin Infusion (CSII) pump with Automatic Insulin Delivery (AID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Virtual Reality Distraction Technique for Anxiety and Pain Control in Orthopedic Forearm Surgeries Performed Under Supraclavicular Brachial Plexus Block
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: VR|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patient Satisfaction and Color Difference Between Natural Teeth and Monolithic All-ceramic Crowns Fabricated From Celtra Press Treated With Different Surface Finishing Protocols
Status: UNKNOWN
Conditions: Natural Optical Properties
Interventions: OTHER: polished celtra press full coverage crown|OTHER: glazed celtra press full coverage crowns|OTHER: contralateral natural teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study of Oral TG02 Capsule in the Treatment of Recurrent / Progressive High-grade Glioma Patients
Status: UNKNOWN
Conditions: High-grade Gliomas
Interventions: DRUG: TG02 capsules oral administration, BIW in every 28d|DRUG: TG02 capsules oral administration, BIW in every 28d|DRUG: TG02 capsules oral administration, BIW in every 28d
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva for Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab|DRUG: erlotinib HCl|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Alignment Level (PAL) Instrument Evaluation
Status: TERMINATED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DEVICE: Pelvic Alignment Level (PAL) Instrument|DEVICE: No Pelvic Alignment Level (PAL) Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Imatinib mesylate|DRUG: Imatinib mesylate|DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Maca Root to Treat Sexual Dysfunction Associated With the Treatment Regimen for Bipolar Disorder in Females
Status: TERMINATED
Conditions: Sexual Dysfunction|Bipolar Disorder
Interventions: DRUG: Maca Root|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab and Induction Chemotherapy for Larynx Preservation in Resectable Advanced Laryngeal/Hypopharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: Laryngeal Cancer|Hypopharynx Cancer|Laryngeal Neoplasms
Interventions: DRUG: chemotherapy TP regimen combined with Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension|Idiopathic Pulmonary Arterial Hypertension|Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)|Connective Tissue Diseases
Interventions: DRUG: 129Xe Hyperpolarized
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: China-Administration of Nicorandil Group（CHANGE）
Status: COMPLETED
Conditions: Myocardial Infarction|Percutaneous Coronary Intervention|Nicorandil
Interventions: DRUG: Nicorandil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Single-dose Magnesium Salts
Status: COMPLETED
Conditions: Bioavailability
Interventions: DIETARY_SUPPLEMENT: Picometer-ionic form of magnesium chloride|DIETARY_SUPPLEMENT: Magnesium citrate or magnesium oxide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study To Compare The Pharmacokinetics Of Different Formulations Of PF-04937319 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pf-04937319|DRUG: Pf-04937319|DRUG: Pf-04937319
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FOcal RECurrent Assessment and Salvage Treatment
Status: UNKNOWN
Conditions: Progression of Prostate Cancer
Interventions: DEVICE: Whole Body MRI|PROCEDURE: Focal Salvage Therapy|PROCEDURE: MRI Targeted biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars
Status: COMPLETED
Conditions: Keloids|Hypertrophic Scars
Interventions: OTHER: Topical silicone gel|OTHER: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OP Device vs. Bone Autograft for the Treatment of Tibial Nonunions
Status: COMPLETED
Conditions: Tibial Nonunions
Interventions: DEVICE: Surgical implantation of OP-1 device or autograft bone graft material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma Detection
Status: RECRUITING
Conditions: Upper Tract Urothelial Carcinoma
Interventions: OTHER: Active Comparator: Surgery Pathology or Cystoscopy|OTHER: Active Comparator: Clinical Diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Interstitial Lung Disease
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease
Interventions: DRUG: Human umbilical cord mesenchymal stem cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Midazolam Versus Intranasal Ketamine to Sedate Newborns for Intubation in Delivery Room
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome|Prematurity of Fetus
Interventions: DRUG: Sedation by ketamine|DRUG: Sedation with Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AngongNiuhuang Pill in Patients With Acute Ischemic Stroke (ANGONG TRIAL)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: AngongNiuhuang pill|DRUG: Placebo of AngongNiuhuang pill|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Vedolizumab IV|DRUG: Vedolizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Open-label Phase III Trial of REduced Frequency Pembrolizumab immuNothErapy for First-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell
Interventions: DRUG: Pembrolizumab 25 MG/ML [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Dexmedetomidine on Lung Protection Following Thoracic Aorta Surgery With Hypothermic Circulatory Arrest: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Chronic Dissecting Aneurysm of Thoracic Aorta|Chronic Nontraumatic Dissection of Thoracic Aorta|Dissecting Aneurysm of the Thoracic Aorta
Interventions: DRUG: Dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lactobacillus Reuteri Strain Combination in Children Treated With PPI
Status: UNKNOWN
Conditions: Gastric Lesion|Proton Pump Inhibitor Adverse Reaction|Probiotic
Interventions: DIETARY_SUPPLEMENT: Gastrus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Breastfeeding Education Given to Family Members on Breastfeeding Parameters
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: breastfeeding education for family members|OTHER: receiving routine breastfeeding training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glioma Intraoperative MicroElectroCorticoGraphy
Status: NOT_YET_RECRUITING
Conditions: Glioma|Epilepsy
Interventions: DEVICE: PANAXIUM MicroECoG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis
Status: NOT_YET_RECRUITING
Conditions: Neurotrophic Keratitis
Interventions: DRUG: BRM424 Ophthalmic Solution - Dose1|DRUG: BRM424 Ophthalmic Solution - Dose2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The TIME-2 Study: A Phase 2 Study of AKB-9778, a Novel Tie-2 Activator, in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema (DME)
Interventions: DRUG: AKB-9778|DRUG: ranibizumab|DRUG: Placebo|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Stigma in People Who Inject Drugs (PWID) With HIV Using a Rapid Start Antiretroviral Therapy Intervention (ART)
Status: NOT_YET_RECRUITING
Conditions: Hiv|Drug Use
Interventions: BEHAVIORAL: Rapid-Start ART (RS-ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects
Status: COMPLETED
Conditions: COVID 19
Interventions: DRUG: HLX71|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Methylene Blue Against Vivax Malaria in Ethiopia
Status: WITHDRAWN
Conditions: Vivax Malaria
Interventions: DRUG: Artemeter-Lumefantrine and MB (combination therapy)|DRUG: Artemeter-Lumefantrine (combination therapy)|DRUG: Artemeter-Lumefantrine and Primaquine (combination therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Standardized Intervention to Improve the Management of Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck|Chemotherapy Induced Nausea and Vomiting
Interventions: OTHER: nurse-led standardized intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Delirium Treatment With Acupuncture in Internal Medicine Departments
Status: COMPLETED
Conditions: Delirium in Old Age
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT