pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Efficacy and Safety of DV890 in Patients With COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia, Impaired Respiratory Function
Interventions: DRUG: DFV890|DRUG: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-PNCL vs fURS in Management of Nephrolithiasis
Status: COMPLETED
Conditions: Nephrolithiasis|Kidney Stone
Interventions: PROCEDURE: Flexible ureteroscopy|PROCEDURE: Mini-percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Sodium Phosphate Tablets vs PEG for Bowel Cleansing
Status: COMPLETED
Conditions: Colon Cleansing
Interventions: DRUG: oral sodium phosphate tablets|DRUG: polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapamycine vs Placebo for the Treatment of Inclusion Body Myositis
Status: COMPLETED
Conditions: Inclusion Body Myositis (IBM)
Interventions: DRUG: Rapamycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOR-SYS: The Norwegian Stroke in the Young Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Death|Carotid Artery Disease|Cardiovascular Disease|Peripheral Artery Disease
Interventions: BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Added Value of Telephone Follow Up and Home Visits in Helping Children to Grow Up Healthy
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Brief Motivational Counseling (BMC)|BEHAVIORAL: Brief Motivational Counseling Plus Phone Calls (BMC + Phone)|BEHAVIORAL: Brief Motivational Counseling Plus Home Visits (BMC + Home)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological Drug Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate and a First Biological Drug
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Blood sample|DIAGNOSTIC_TEST: CRQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Systemic Exposure of FLIXOTIDE™ (Fluticasone Propionate) and SERETIDE™ (Fluticasone Propionate and Salmeterol) Given With VENTOLIN™ Mini-Spacer Compared to the Aerochamber Plus Spacer
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: VENTOLIN Mini-Spacer|DEVICE: Aerochamber Plus spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing MICARDIS® (Telmisartan) and COZAAR® / LORZAAR® (Losartan) in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring (ABPM)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: High dose of MICARDIS®, once daily|DRUG: Low dose of MICARDIS®, once daily|DRUG: Low dose of COZAAR® / LORZAAR®, once daily|DRUG: High dose of COZAAR® / LORZAAR®, once daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vagus Nerve Stimulation (VNS) as a Treatment of Persistent Depression With Comorbid Personality Disorders (Impulse-VNS
Status: WITHDRAWN
Conditions: Depression|Comorbid Personality Disorders
Interventions: DEVICE: VNS Pulse Model 102|DEVICE: VNS Pulse Model 102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma
Status: RECRUITING
Conditions: Folliculotropic Mycosis Fungoides|Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Sezary Syndrome|Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8|Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8|Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v8|Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v8|Transformed Mycosis Fungoides
Interventions: PROCEDURE: Extracorporeal Photopheresis|BIOLOGICAL: Mogamulizumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Resuscitation in Open Aortic Surgery
Status: UNKNOWN
Conditions: Aortic Diseases
Interventions: DIAGNOSTIC_TEST: Point of Care Ultrasound (POCUS)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Silicone Hydrogel Monthly Lenses
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Lotrafilcon B contact lenses|DEVICE: Senofilcon C contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Garlic Tablet Some Indicators Related to Atherosclerosis
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Garlic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Allopurinol on Mono and Co-administration With Statins on Platelets Reactivity on Diabetic Patiets Treated With Aspirin and Insulin
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2 Platelets Reactivity Statin
Interventions: DRUG: Atorvastatin 80mg|DRUG: ALLOPURINOL 300 MG|DRUG: Atorvastatin 80mg AND allopurinol 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MSPrebiotic on Gastrointestinal Function and Blood Glucose Levels
Status: COMPLETED
Conditions: Gastrointestinal Function
Interventions: DIETARY_SUPPLEMENT: MSPrebiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TAK-442 in Subjects With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ALD403 (Eptinezumab) in the Prevention of Chronic Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: BIOLOGICAL: ALD403 (Eptinezumab)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human Placenta Mesenchymal Stem Cells Derived Exosomes Injection for Treatment of Complex Anal Fistula
Status: NOT_YET_RECRUITING
Conditions: Fistula Perianal
Interventions: PROCEDURE: exosome|PROCEDURE: routine conventional fistulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Minisling Versus Transobturator (TOT)Sling
Status: COMPLETED
Conditions: Female Stress Urinary Incontinence
Interventions: PROCEDURE: Mini-sling|PROCEDURE: Transobturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.
Status: COMPLETED
Conditions: Generalized Aggressive Periodontitis
Interventions: DRUG: Triclosan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours
Status: COMPLETED
Conditions: Advanced or Metastatic Biliary Tract Cancer|Advanced or Metastatic Solid Tumors
Interventions: DRUG: varlitinib|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Outpatient Closed Loop Control With the iLet Bionic Pancreas in Cystic Fibrosis Related Diabetes
Status: COMPLETED
Conditions: Cystic Fibrosis-related Diabetes
Interventions: DEVICE: Bionic Pancreas|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: EOS789|DRUG: Placebo|DRUG: Renvela
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Four Versus Six Cycles of Pemetrexed/Platinum for MPM
Status: UNKNOWN
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: pemetrexed/platinum chemotherapy|DRUG: Pemetrexed/platinum chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors
Status: RECRUITING
Conditions: Stroke|Walking, Difficulty|Cardiovascular Injury
Interventions: OTHER: Gait Training|OTHER: Leg Cycling Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling up Women's Agripreneurship Through Public-private Linkages in Rural Ghana
Status: COMPLETED
Conditions: Women's Health|Low Income Populations
Interventions: BEHAVIORAL: Entrepreneurial stimulation and integrated education|BEHAVIORAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Feeding Modes in Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|BEHAVIORAL: Basic treatment|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of FluBlok Trivalent Recombinant Hemagglutinin Influenza Vaccine in Healthy Pediatrics
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Vaccination|BIOLOGICAL: Influenza Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Glycemic Control for Congestive Heart Failure Exacerbation
Status: COMPLETED
Conditions: Congestive Heart Failure|Diabetes Mellitus
Interventions: DRUG: Intravenous insulin|DRUG: Subcutaneous insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Anorexia Nervosa on Bone Mass in Adolescents
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: Physiologic Estrogen/progesterone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in Vitro
Status: RECRUITING
Conditions: Epidermolysis Bullosa Dystrophica
Interventions: OTHER: Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: F901318 Single Ascending Dose Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Invasive Aspergillosis
Interventions: DRUG: F901318|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Doses of ZP4207 Administered in HV and in T1D to Evaluate Safety, Tolerability PKs and PDs of ZP4207 Compared to a Comparator
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: ZP4207|DRUG: Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Colesevelam hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Health Education|OTHER: Home Blood Pressure Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NPC-06 to Pain Associated With Acute Herpes Zoster
Status: COMPLETED
Conditions: Acute Pain in Herpes Zoster
Interventions: DRUG: NPC-06|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human (FIH) Study of the Xeltis Hemodialysis Access Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease|End Stage Renal Failure on Dialysis
Interventions: DEVICE: aXess
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Chidamide in Combination With Exemestane in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Chidamide|DRUG: exemestane|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Short-term Comparative Study of Aerosure for Airway Clearance in Patients With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Aerosure at 15 Hz|DEVICE: Aerosure at 25 Hz|DEVICE: Sham Aerosure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Primaquine Enantiomers in G6PD Deficient Human Volunteers
Status: UNKNOWN
Conditions: G6PD Deficiency
Interventions: DRUG: RPQ|DRUG: SPQ|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AZD7268 Single Ascending Dose Study in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD7268|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Baclofen for Improving Benzodiazepine Titration in Benzodiazepine Dependence
Status: NOT_YET_RECRUITING
Conditions: Benzodiazepine Dependence
Interventions: DRUG: Baclofen 30 mg|DRUG: Baclofen 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Maintaining Dosage in Acute Coronary Syndrome After Drug Eluting Stent Implantation
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy
Status: RECRUITING
Conditions: Locally Advanced Bladder Urothelial Carcinoma|Locally Advanced Renal Pelvis Urothelial Carcinoma|Locally Advanced Ureter Urothelial Carcinoma|Locally Advanced Urethral Urothelial Carcinoma|Locally Advanced Urothelial Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Recurrent Bladder Urothelial Carcinoma|Recurrent Renal Pelvis Urothelial Carcinoma|Recurrent Ureter Urothelial Carcinoma|Recurrent Urethral Urothelial Carcinoma|Recurrent Urothelial Carcinoma|Stage IIIB Bladder Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Enfortumab Vedotin|DRUG: Erdafitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultra Processed Versus Unprocessed Diets on Energy Intake
Status: COMPLETED
Conditions: Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Ultra-processed diet|DIETARY_SUPPLEMENT: Unprocessed diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Fecal Microbiota Transplatation on Axial Spondyloarthritis Patients Resistant to Conventional Treatment
Status: RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: DRUG: active FMT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Relapsed and Refractory Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Newly Diagnosed Glioblastoma
Interventions: DEVICE: Optune|DRUG: Gadolinium|DRUG: Temozolomide|RADIATION: Stereotactic radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Spinal Anesthesia|General Anesthesia|Postoperative Pain
Interventions: PROCEDURE: laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy vs. Chemotherapy With Radical Gastrectomy and Adjuvant Chemotherapy for Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: RADIATION: Neoadjuvant Chemoradiotherapy|DRUG: Neoadjuvant Chemotherapy|PROCEDURE: R0 D2 Gastrectomy|DRUG: Adjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biomarkers Based on Fine-Needle Aspiration in Women at Increased or Normal Risk of Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: OTHER: cytology specimen collection procedure|PROCEDURE: comparison of screening methods|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Tinidazole Versus Cefazolin Antibiotic Prophylaxis of Vaginal and Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Hysterectomy
Interventions: DRUG: cefazolin|DRUG: tinidazole|DRUG: cefazolin plus tinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Mindfulness Based Intervention in Reducing Stress Levels of Anesthesiology and Intensive Therapy Residents at the Faculty of Medicine, University of Indonesia
Status: COMPLETED
Conditions: Anesthesiology and Intensive Therapy Residents at the Faculty of Medicine, University of Indonesia
Interventions: OTHER: Mindfulness Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the Non-Pneumatic Anti-Shock Garment (NASG) in Egypt
Status: COMPLETED
Conditions: Hypovolemic Shock|Hemorrhage
Interventions: DEVICE: Non-pneumatic Anti-shock Garment (NASG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Care Delivery of HIV Prevention and Treatment in AGYW in Zambia
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization)|OTHER: Integrated wellness care (IWC) clinics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-Resolution Anoscopy Perceived Discomfort Study
Status: COMPLETED
Conditions: Pain|Anal Cancer
Interventions: PROCEDURE: Perianal Exam|PROCEDURE: high-resolution anoscopy (HRA) with biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DL6049 Versus Cosmoplast in the Treatment of Nasolabial Fold Wrinkles, Long Term Follow-up
Status: COMPLETED
Conditions: Nasolabial Fold Wrinkles
Interventions: DEVICE: DL6049 (injectable poly-L-lactic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Multiple Sensory Interventions On Infants' Pain and Physiological Distress During Neonatal Screening Procedures
Status: COMPLETED
Conditions: Infant Behavior|Pain, Acute|Physiological Stress|Breast Milk
Interventions: BEHAVIORAL: GT+VC|BEHAVIORAL: Smell|BEHAVIORAL: Taste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Home-Based Technologies Coupled to Teleassistance Service in the Elderly
Status: UNKNOWN
Conditions: Disablement in the Elderly
Interventions: OTHER: home automation pack coupled to teleassistance service|OTHER: Home without automation pack coupled to teleassistance service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of a Protein Calorie Supplement in HIV-infected Women With Tuberculosis
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Protein calorie supplement|DIETARY_SUPPLEMENT: Micronutrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Function and Gynecological Profile of Patients Carrying a Pathogenic Variant of the HNF1B Gene (GYN-HNF1)
Status: COMPLETED
Conditions: Genital Diseases, Female
Interventions: OTHER: Pelvic ultrasound|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Extended-release Bupropion Hydrochloride Tablets in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Bupropion HCl XL tablet 150mg|DRUG: Bupropion HCl XL tablet 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous MSC Therapy on Ischemia-Reperfusion Injury in Patients With Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction
Interventions: BIOLOGICAL: WJ-MSC cells implantation|DRUG: CTSTMD PBS without WJ-MSC|DRUG: Conventional drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sternotomies and PectoIntercostal Fascia Blocks in Fast-Track Cardiac Anesthesiology
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: PROCEDURE: Pectointercostal fascia blocks|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: BIOLOGICAL: Liberal platelet transfusion|BIOLOGICAL: Restrictive platelet transfusion|DRUG: Paracetamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries
Status: SUSPENDED
Conditions: Spinal Cord Injury
Interventions: PROCEDURE: Autologous Incubated Macrophages (cell therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10 Weeks of NIntendo wIi Fit balanCe Training Improved Postural balANce and Muscle Strength in Elderly Individuals
Status: COMPLETED
Conditions: Impaired Balance
Interventions: OTHER: Nintendo wii balance training|OTHER: EVA-soles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of BI6727 (Volasertib) and BIBF1120 in Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 6727|DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine, Metabolic, Cardiovascular and Immunological Aspects of Sex Chromosome Abnormalities in Relation to Genotype
Status: RECRUITING
Conditions: Sex Chromosome Abnormality|Klinefelter Syndrome|Turner Syndrome|Metabolic Disease|Cardiovascular Diseases|Immunologic Disease
Interventions: OTHER: No intervention other than obtaining biopsies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Primary Patency in Post-angioplasty Dysfunctional Arteriovenous Fistula in Renal Dialysis: Paclitaxel-releasing PTA Balloon Catheter vs PTA Balloon
Status: COMPLETED
Conditions: Arteriovenous Fistula Renal Dialysis Devices Obstruction
Interventions: DEVICE: Paclitaxel-releasing PTA balloon catheter|DEVICE: PTA balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video Game-Brain Functioning Reversibility Study
Status: UNKNOWN
Conditions: Brain Functioning and Violent Video Game Play
Interventions: BEHAVIORAL: Control group with no video game play|BEHAVIORAL: control 2|BEHAVIORAL: VG1 group (2 weeks of violent video game play)|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Laparoscopic Gastric Function Preserving Surgery Combined With Resection of the Anterior Lymphatic Drainage Area
Status: RECRUITING
Conditions: Gastric Cancer Stage I
Interventions: PROCEDURE: Laparoscopic gastric function preserving surgery combined with resection of the anterior lymphatic drainage area
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: First in Men Study: BIOMAG-I
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Implantation of a Sirolimus-Eluting Resorbable Coronary Magnesium Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: AG-920|DRUG: Proparacaine Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy/Safety Study of Bevacizumab,Capecitabine,Oxaliplatin to Metastatic Colorectal Adenocarcinoma Elderly Patients.
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: bevacizumab, capecitabine, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Internet-based Stress Management Among Adults With a Cardiovascular Disease: A Pilot Sequential Multiple Assignment Randomized Trial (SMART) Design
Status: COMPLETED
Conditions: Cardiovascular Diseases|Stress, Psychological
Interventions: BEHAVIORAL: My Health CheckUp Online Stress Management Program|BEHAVIORAL: Lay telephone coaching|BEHAVIORAL: Motivational interviewing (telephone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study Designed to Study the Effects of Two Different Doses of CXA-101/Tazobactam, a Low Dose and a High Dose, on the QT/QTc Intervals in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CXA-101/tazobactam|DRUG: CXA-101/tazobactam|DRUG: Moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy and Computer-Planned Radiation Therapy in Treating Patients With Unresectable Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars
Status: RECRUITING
Conditions: Dental Caries|Dental Diseases|Deep Caries|Tooth Diseases|Tooth Decay|Teeth; Lesion|Caries; Dentin|Dental Restoration Failure of Marginal Integrity|Tooth Demineralization
Interventions: OTHER: selective caries removal and conventional non-bioactive restorative system|OTHER: selective caries removal and bioactive restorative system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAVA vs. CMV Crossover in Severe BPD
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia|Neurally Adjusted Ventilatory Assist|Mechanical Ventilation
Interventions: DEVICE: NAVA|DEVICE: CMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits
Status: NOT_YET_RECRUITING
Conditions: Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: OTHER: QI toolkit implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Low-molecular Weight Heparin for Thromboprophylaxis in Acutely Ill Medical Patients
Status: COMPLETED
Conditions: Embolism
Interventions: DRUG: Certoparin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination of Recombinant Human IL-21 (rIL-21) and Sunitinib in Stage IV Renal Cell Carcinoma Patients
Status: COMPLETED
Conditions: Cancer|Renal Cell Carcinoma
Interventions: DRUG: recombinant interleukin-21|DRUG: sunitinib|DRUG: recombinant interleukin-21|DRUG: recombinant interleukin-21|DRUG: recombinant interleukin-21
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blinded, Placebo Controlled, Monocentric Study to Evaluate the Anti-ageing and Skin Brightening Benefit of the Test Product in Healthy Female Subjects
Status: COMPLETED
Conditions: Skin Aging
Interventions: OTHER: Terminalia Chebula Fruit Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Low Level Laser Therapy on Pain Occurring After Insertion of an Orthodontic Device
Status: COMPLETED
Conditions: Bad Molar Teeth Arrangement Requiring Orthodontic Device
Interventions: DEVICE: Low level laser therapy|PROCEDURE: sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Effectiveness, Safety and Tolerability of Treatment, Using a PSMA-Lu177, in Patients With ACC- an Open, Non-commercial Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Lutetium (177Lu) vipivotide tetraxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring for Hyperglycemia in Critically Ill Patients
Status: RECRUITING
Conditions: Hyperglycemia|Hypoglycemia|Critical Illness|Diabetes Mellitus
Interventions: DEVICE: Continuous glucose monitoring|DEVICE: Point of care glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of EpCAM Receptors Using [123I]I-DARPIN-Ec1
Status: ENROLLING_BY_INVITATION
Conditions: Lung Cancer|Ovarian Cancer
Interventions: DRUG: Diagnostic injection of [123I]I-DARPIN-Ec1|DIAGNOSTIC_TEST: Whole-body planar scintigraphy with [123I]I-DARPIN-Ec1|DIAGNOSTIC_TEST: Whole-body SPECT with [123I]I-DARPIN-Ec1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Yoga Asana 'Vrksasana (Tree Pose)' on Balance in the Patients With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: OTHER: Conservative exercise group|OTHER: Tree pose added exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Treatment With Cetuximab and/or IMC-A12
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Cetuximab|DRUG: IMC-A12|PROCEDURE: Surgical tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
Status: COMPLETED
Conditions: Urinary Tract Infection|Pelvic Organ Prolapse|Urinary Incontinence
Interventions: DRUG: L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interpretability of the Quantra® Viscoelastic Test in Patients With Haematological Malignancies With Profound Thrombocytopenia Below 50x10 G/L.
Status: RECRUITING
Conditions: Hematologic Malignancies|Thrombopenia
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Lymphedema Evaluation After Adjuvant Hypofractionated Radiotherapy for 1-2 Macrometastatic Sentinel Lymph Nodes
Status: RECRUITING
Conditions: Arm Lymphedema|Breast Cancer|Radiotherapy Side Effect
Interventions: RADIATION: Hypofractionated radiotherapy scheme
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Osmotic Release Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.
Status: COMPLETED
Conditions: Infection, Fungal
Interventions: DRUG: Cumin seed extract|DRUG: clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial to Assess Safety of UV Phototherapy for the Prevention of GVHD Post Allogeneic SCT
Status: WITHDRAWN
Conditions: Allogeneic Transplantation (Non T-cell Depleted)
Interventions: DEVICE: EUMATRON - EN 600 NT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opiates and Benzodiazepines on Driving
Status: COMPLETED
Conditions: Driving Behavior
Interventions: DRUG: Xanax 1Mg Tablet|DRUG: Norco 10Mg-325Mg Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)
Status: COMPLETED
Conditions: Conjunctivitis, Vernal
Interventions: DRUG: Cyclosporine NOVA22007 0.05%|DRUG: Cyclosporine NOVA22007 0.1%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Buprenorphine/Naloxone Stabilization and Induction Onto Injection Naltrexone
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes Between Lenticule Extraction and Femtosecond Laser-assisted Laser in Situ Keratomileusis
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: lenticule extraction|PROCEDURE: femtosecond laser-assisted laser in situ keratomileusis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery
Status: RECRUITING
Conditions: Inferior Alveolar Nerve Injuries|Impacted Third Molar Tooth
Interventions: RADIATION: 3D-CBCT|RADIATION: 2D-OPG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of 'GC3110A(QIV)' in Healthy Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GC3110A|BIOLOGICAL: GCFLU Pre-filled Syringe inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: NIS793|DRUG: Bevacizumab|DRUG: Modified FOLFOX6|DRUG: FOLFIRI|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer
Status: COMPLETED
Conditions: Melanoma|Liver Cancer|Pancreatic Cancer|Lung Cancer
Interventions: BIOLOGICAL: Recombinant hGM-CSF Herpes Simplex Virus Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurochemical Modulation Cognitive Performance and Subjective Wellbeing In Healthy Controls
Status: COMPLETED
Conditions: Cognitive Performance|Creativity|Motivation|Reward|Healthy Volunteers|Subjective Pleasure
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Antibiotic Treatment on Prostate-Specific Antigen (PSA) Variability
Status: TERMINATED
Conditions: Prostate Infections
Interventions: DRUG: Ciprofloxacin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Conservative Surgery in Treating Patients With Low-Risk Stage IA2 or IB1 Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Adenocarcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|Stage IA2 Cervical Cancer AJCC v6 and v7|Stage IB1 Cervical Cancer AJCC v6 and v7
Interventions: PROCEDURE: Lymph Node Mapping|OTHER: Quality-of-Life Assessment|PROCEDURE: Salpingo-Oophorectomy|PROCEDURE: Sentinel Lymph Node Biopsy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Skin to Skin Contact on Sucking Efficiency of Newborns and Breastfeeding Self Efficacy of Mothers in Cesarean Deliveries
Status: COMPLETED
Conditions: Nurse's Role|Breastfeeding
Interventions: BEHAVIORAL: Skin-to-Skin contact.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Parent-to-parent Coaching While Awaiting Hospital Discharge With a Child With a Ventilator
Status: RECRUITING
Conditions: Invasive Mechanical Ventilation|Children With Medical Complexity|Home Nursing|Empowerment
Interventions: BEHAVIORAL: Parent-to-parent coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Olaparib|RADIATION: Pelvic external beam radiotherapy|DRUG: Chemotherapy|DRUG: Durvalumab|DRUG: Medroxyprogesterone Acetate|DRUG: Megestrol Acetate|RADIATION: Vaginal brachytherapy|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previously
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Insulin Glargine Versus Twice-Daily NPH
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine at bedtime instead of NPH|DRUG: NPH twice-daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
Status: COMPLETED
Conditions: Macromastia
Interventions: DEVICE: PEAK PlasmaBlade|PROCEDURE: Traditional Electrosurgery with scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin With or Without Gemcitabine in Treating Patients With Advanced Ovarian Epithelial Cancer That Has Not Responded to Previous Chemotherapy
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT