pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Improving Exercise Capacity With a Tailored Physical Activity Intervention
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma|Heart; Functional Disturbance|Hodgkin Lymphoma|Quality of Life|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: OTHER: Exercise with Trainerize application|DIAGNOSTIC_TEST: Cardiopulmonary exercise testing|DIAGNOSTIC_TEST: MRI scan|BEHAVIORAL: Quality of Life Questionnaires|BEHAVIORAL: Cognitive and Brain Function Questionnaires|OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer
Status: COMPLETED
Conditions: Locally Advanced Cervical Cancer
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin + Re-induction Chemotherapy for AML
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Brentuximab Vedotin|DRUG: Mitoxantrone|DRUG: Etoposide|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azimilide for the Treatment of Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Azimilide Dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip Replacement
Status: UNKNOWN
Conditions: Total Hip Arthroplasty
Interventions: DRUG: Levobupivacaine|DRUG: Intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
Status: COMPLETED
Conditions: Myotonic Dystrophy Type 1
Interventions: DRUG: rhIGF-I/rhIGFBP-3|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Concordance Between Pre-therapy Dosimetry Performed From 68Ga-PSMA-11 Dynamic PET and Post-treatment Dosimetry of 177Lu-PSMA-617 Vectorized Internal Radiotherapy in Patients With Metastatic Prostate Cancer Resistant to Hormonal Castration.
Status: NOT_YET_RECRUITING
Conditions: Patients With Metastatic Castration-resistant Prostate Cancer
Interventions: RADIATION: 177Lu-PSMA-617 PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tofacitinib For Treatment Of Chronic Pouchitis
Status: TERMINATED
Conditions: Pouchitis|Ileal Pouchitis|Ileal Pouch
Interventions: DRUG: Tofacitinib 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic
Status: COMPLETED
Conditions: Dyslipidemias|Cardiovascular Diseases|Hypertriglyceridemia
Interventions: DRUG: fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bradykinin-degradating Enzymes Activities in Angiotensin-Converting Enzyme Inhibitors-associated Angioedema
Status: RECRUITING
Conditions: Angio-Oedema Caused by Angiotensin-Converting-Enzyme Inhibitor
Interventions: OTHER: Assay of Bradykinin-degradating enzymes.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignancy|Advanced Solid Tumors|Cancer|Solid Tumors|Tumors
Interventions: DRUG: Arm 1- Dose Escalation|DRUG: Arm 1- Dose Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence (ALC-DRD2-APO)
Status: UNKNOWN
Conditions: Alcoholism
Interventions: DRUG: apomorphine|DRUG: [(123)I] iodobenzamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of High-intensity Inspiratory Muscle Training in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Status: COMPLETED
Conditions: Complications Due to Coronary Artery Bypass Graft
Interventions: DEVICE: High-intensity IMT + combined exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: ketoprofen and cyclobenzaprine association with caffeine|DRUG: Cyclobenzaprine with caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establishing Technique for PECS2 Catheter Insertion
Status: COMPLETED
Conditions: Breastcancer|Phyllodes Breast Tumor
Interventions: PROCEDURE: Pectoralis II block & catheter without Lidocaine dissection|PROCEDURE: Pectoralis II block & catheter with Lidocaine dissection|OTHER: catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Pfs25M-EPA|BIOLOGICAL: Pfs230D1M-EPA|OTHER: AS01|BIOLOGICAL: Engerix-B|BIOLOGICAL: Menactra|OTHER: Normal Saline|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sensory Versus Motor Level Neuromuscular Electrical Stimulation
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Chemotherapy Effect|Chemotherapeutic Toxicity
Interventions: DRUG: Oxaliplatin,calcium folinic acid, levofolinic acid, 5-FU|DRUG: Concurrent Lenvatinib|DRUG: Concurrent PD-1 antibody|DRUG: Sequential Lenvatinib|DRUG: Sequential PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking With the SAIRE Smart Walker
Status: RECRUITING
Conditions: Gait Disorders in Old Age|Gait Disorders, Neurologic|Walking, Difficulty
Interventions: DEVICE: SAIRE smart walker|DEVICE: Standard 4-wheeled walker|OTHER: No walking aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DEVICE: Selective Cytopheretic Device|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Flavonoids and Phenolic Acids From Cranberry Juice Cocktail in Healthy Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Low calorie, sugar-free cranberry juice cocktail (54% juice)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Traumatic Brain Injury
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously
Status: COMPLETED
Conditions: Pain|Analgesia, Patient-Controlled|Pain, Postoperative
Interventions: DRUG: IONSYS (fentanyl HCl) Iontophoretic TransdermalSystem|DRUG: IV Morphine Patient-Controlled Analgesia (IV PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Belatacept in Subjects Who Are Undergoing a Renal Transplant
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Cyclosporin A|DRUG: Belatacept Less Intensive Regimen (LI)|DRUG: Belatacept More Intensive Regimen (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)
Status: RECRUITING
Conditions: Calcific Aortic Valve Disease
Interventions: DRUG: Evogliptin|DRUG: Evogliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Proteomic Study and Early Intervention Study of Carotid Unstable Plaque
Status: NOT_YET_RECRUITING
Conditions: Protein; Disease|Carotid Artery Plaque|Traditional Chinese Medicine
Interventions: DRUG: Qushi Formula|DRUG: Zhu's Wenban Formula|DRUG: placebo|OTHER: Basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Venous Pressure Guided Hydration Prevention for Contrast-Induced Nephropathy
Status: COMPLETED
Conditions: Cardio-Renal Syndrome
Interventions: PROCEDURE: hydration|DRUG: Visipaque|DRUG: 0.9% sodium chloride ﬂuid administration|DEVICE: 5-French catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of PillCam IBD Capsule Endoscopy System in Visualization of Lesions in the Colon Indicative of Ulcerative Colitis Disease
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DEVICE: Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In-Vivo Comparison of Different Impression Methods in Complete Edentulous Upper Jaw
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: OTHER: Edentulous maxilla final impression for complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients
Status: TERMINATED
Conditions: Pancreatic Cancer|Cancer of the Pancreas|Pancreas Cancer
Interventions: DRUG: CDX-301|DRUG: CDX-1140|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Accuracy Improvement of Repeated Measure Uroflowmetry- Electromyography
Status: UNKNOWN
Conditions: Enuresis
Interventions: BIOLOGICAL: Combining electromyography with uroflowmetry (group A)|BIOLOGICAL: Uroflowmetry(Group B)|BIOLOGICAL: Uroflowmetry-Combining electromyography with uroflowmetry (Group C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Status: RECRUITING
Conditions: Depression|Alcoholism|Drug Abuse
Interventions: BEHAVIORAL: Interpersonal and Social Rhythm Therapy (ISRT)|BEHAVIORAL: Bipolar-Specific Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)|BEHAVIORAL: Psycho-education & Understanding Bipolar Medications Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amsterdam Investigator-initiateD Absorb Strategy All-comers Trial
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Infarction
Interventions: DEVICE: ABSORB BVS™|DEVICE: XIENCE™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Between Laparoscopic Gastric Bypass and Laparoscopic Vertical Banded Gastroplasty for Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic gastric bypass|PROCEDURE: Laparoscopic VBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT: WLE vs. NBI in Upper Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Gastric Intestinal Metaplasia|Gastric Cancer
Interventions: DEVICE: narrow band imaging|DEVICE: white light endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Effect of Yizhi Baduanjin on Patients With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Yizhi Baduanjin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholesterol Reduction in Seniors Program (CRISP)
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Diseases|Coronary Disease|Heart Diseases|Hypercholesterolemia|Myocardial Ischemia
Interventions: DRUG: lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Impact of Sending an Sms on the Rate of Telephone Responses of Subjects Contacted 3 Months After the Suicidal Act
Status: NOT_YET_RECRUITING
Conditions: Suicide, Attempted
Interventions: OTHER: IMPACT OF SENDING AN SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia
Status: COMPLETED
Conditions: Acute Undifferentiated Leukemia|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Mast Cell Leukemia|Myeloid/NK-cell Acute Leukemia|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: PROCEDURE: bioelectric impedance analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using A Dissolved Oxygen Enriched Dressing in Nipple-sparing Mastectomy
Status: TERMINATED
Conditions: Breast Cancer|Reconstructive Breast Surgery
Interventions: DEVICE: OxyGenesys Dissolved Oxygen Dressing|DEVICE: Standard Gauze Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DRUG: placebo|DRUG: travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Use & Open Fracture of the Lower Extremity
Status: SUSPENDED
Conditions: Lower Extremity Fracture
Interventions: DRUG: Cephalosporin 1St Generation|DRUG: Aminoglycosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Epigenetics, Vitamin C and Abnormal Hematopoiesis - Pilot Study
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Intervention in Primary Open-angle Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Glaucoma, Open-Angle|Glaucoma
Interventions: BEHAVIORAL: Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
Status: RECRUITING
Conditions: Glaucoma
Interventions: PROCEDURE: Sulcus tube placement|PROCEDURE: Anterior chamber (AC) tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer
Status: RECRUITING
Conditions: Olanzapine|CINV|Testicular Cancer by AJCC V6 and V7 Stage|Cisplatin
Interventions: DRUG: Olanzapine Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Semaglutide on Nicotine Intake
Status: COMPLETED
Conditions: Tobacco Use Disorder|Nicotine Addiction
Interventions: DRUG: Semaglutide|DRUG: Sham/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plus Epicatechin Duchenne Muscular Dystrophy in Non-ambulatory Adolescents
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: (+)- Epicatechin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ulocuplumab and Nivolumab in Subjects With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Ulocuplumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RCT on Telerehabilitation Efficacy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: VRRS Tablet (Khymeia s.r.l., Noventa Padovana, Italy)|OTHER: At-home conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of AlloMap Molecular Testing and Traditional Biopsy-based Surveillance for Heart Transplant Rejection Early Post-transplantation
Status: UNKNOWN
Conditions: Graft Rejection|Heart Diseases
Interventions: PROCEDURE: Endomyocardial biopsy|PROCEDURE: AlloMap Molecular Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Physiologic saline|DRUG: Magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Neoadjuvant Study of Androgen Ablation Combined With Cyclophosphamide and GVAX Vaccine for Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Adenocarcinoma in Situ
Interventions: DRUG: degarelix acetate|DRUG: Cyclophosphamide|DRUG: GVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Protection in Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Severe Symptomatic Calcified Native Aortic Valve Stenosis
Interventions: DEVICE: Cerebral Protection System-The SENTINEL System with TAVR|DEVICE: TAVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurocognitive Disorders|Neurodegenerative Diseases|Mental Disorders
Interventions: BEHAVIORAL: Tele-Savvy|BEHAVIORAL: Caregiving During Crisis (Educational Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Take 5 + Audio Clip Randomized Control Trial
Status: COMPLETED
Conditions: Abuse, Child|Crying|Parent-Child Relations
Interventions: BEHAVIORAL: Take 5 and Audio Clip|BEHAVIORAL: Take 5 Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Follow-up of Covid-19 Long Term Sequelae
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Bronchitis|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Lower Respiratory Infection|Covid19|Corona Virus Infection|Coronavirus|Coronavirus Infections|SARS-CoV2 Infection|SARS-CoV-2 Acute Respiratory Disease|SARS-Associated Coronavirus|SARS Pneumonia|SARS (Severe Acute Respiratory Syndrome)|SARS (Disease)|Coronavirus Pneumonia|Coronavirus Disease 2019|Coronavirus Sars-Associated
Interventions: OTHER: Not applicable (observational study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Positive Airway Pressure Ventilation After Acute Ischemic Stroke
Status: COMPLETED
Conditions: Brain Infarction
Interventions: DEVICE: non-invasive continuous positive airway pressure ventilation|DEVICE: CPAP-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation-perfusion (V/Q) Ratio and Alveolar Surface Area in Preterm Infants
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: OTHER: Calculation of ventilation-perfusion ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Association of Ingrown Toenails With Flat Foot, Hallux Abducto Valgus and Hallux Limitus
Status: COMPLETED
Conditions: Ingrown Toe Nail|Flat Foot|Hallux Abductovalgus|Hallux Limitus
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Unspecified, Adult
Interventions: DRUG: Domvanalimab|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: RO7171009
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes
Status: TERMINATED
Conditions: Atrial High Rate Episodes
Interventions: DRUG: Edoxaban|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Determine the Effect of the Fourth Ventricle Compression Technique on Physiological Variables
Status: NOT_YET_RECRUITING
Conditions: Healthy Young Adults
Interventions: OTHER: Fourth ventricle compression technique (CV-4)|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Aliskiren HCTZ vs Ramipril in Obese Patients (BMI ≥ 30) With Stage 2 Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren Hydrochlorothiazide|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Phase 1 Study of Plasmalogen Precursor PPI-1011 in Healthy Adult Volunteers to Assess Safety, Tolerability, and Pharmacokinetics
Status: RECRUITING
Conditions: Rhizomelic Chondrodysplasia Punctata
Interventions: DRUG: PPI-1011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses
Status: COMPLETED
Conditions: Presbyopia|Refractive Errors|Cataract
Interventions: DIAGNOSTIC_TEST: bUDVA, bUIRA, bUNRA, bUICPS, bUNCPS|DIAGNOSTIC_TEST: Contrast sensitivity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Efficacy and Safety of QVM149 With QMF149 in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QVM149 150/50/160|DRUG: QVM149 150/50/80|DRUG: QMF149 150/320|DRUG: QMF149 150/160|DRUG: salmeterol/fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Synbiotic 365 on Body Composition in Overweight and Obese Individuals
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Rice Hulk|OTHER: Synbiotic365 Ver 5|OTHER: Synbiotic365 Ver 7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intermittent Preventive Treatment for Malaria in Infants in Navrongo Ghana
Status: COMPLETED
Conditions: Anaemia|Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Bone Marrow Edema Lesions of the Knee With Percutaneous Grafting
Status: COMPLETED
Conditions: Bone Marrow Edema
Interventions: DEVICE: Percutaneous introduction of cannula|DIAGNOSTIC_TEST: Magnetic resonance imaging|BIOLOGICAL: Bone Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2/Neu Positive|Progesterone Receptor Positive|Recurrent Breast Carcinoma|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7
Interventions: DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Surgical Staplers for the Treatment of Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DEVICE: EEA Hemorrhoid and Prolapse Stapling Set|DEVICE: Endosurgery Proximate PPH03 Stapling Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
Status: COMPLETED
Conditions: Recurrent Tonsillitis|Peritonsillar Abscess|Obstructive Sleep Apnea
Interventions: PROCEDURE: Auricular Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of HFNO on Spontaneous Ventilation in Patients of Different ASA Risk During Analgo-sedation for Vitrectomy
Status: UNKNOWN
Conditions: Noninvasive Ventilation|Respiratory Insufficiency|Moderate Sedation|Hypoxia|Airway Management|Vitrectomy
Interventions: DEVICE: Low-flow nasal oxygenation (LFNO) ASA I|DEVICE: Low-flow nasal oxygenation (LFNO) ASA II|DEVICE: Low-flow nasal oxygenation (LFNO) ASA III|DEVICE: High-flow nasal oxygenation (HFNO) ASA I|DEVICE: High-flow nasal oxygenation (HFNO) ASAII|DEVICE: High-flow nasal oxygenation (HFNO) ASA III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Usefulness of Tacrolimus Without Basiliximab in Well Matched Living Renal Transplantation in Korea
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: DRUG: Basiliximab|DRUG: No basiliximab|PROCEDURE: Kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL) Clinical Study in Japan
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harnessing Health IT to Promote Equitable Care for Patients With Limited English Proficiency and Complex Care Needs
Status: ENROLLING_BY_INVITATION
Conditions: Artificial Intelligence
Interventions: OTHER: Complexity score and implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder (Manic Or Mixed)
Status: WITHDRAWN
Conditions: Bipolar Disorder
Interventions: DRUG: ziprasidone oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Robotic Versus Laparoscopic-assisted Radical Resection for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: robot-assisted total mesorectal excision|PROCEDURE: laparoscopic total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Comorbidities of Attention Deficit Hyperactivity in Children and Adolescents.
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIAGNOSTIC_TEST: IQ assessment using Wechsler intelligence scale for children third edition (WISC-III)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sirolimus DEB in Coronary Bifurcation Lesions
Status: RECRUITING
Conditions: Coronary Bifurcation Lesions
Interventions: DEVICE: Sirolimus drug-eluting coronary balloon catheter|DEVICE: Paclitaxel drug-eluting coronary balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
Status: RECRUITING
Conditions: Trauma|Acute Pain
Interventions: DRUG: Magnesium Sulfate in Parenteral Dosage Form|DRUG: Normal saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Performance of Standard Double Lumen Tubes With Vivasight DL™ Double Lumen Tubes for Lung Isolation in Patients Undergoing Thoracic Surgery
Status: COMPLETED
Conditions: Performance and Safety of an Airway Management Device
Interventions: DEVICE: double lumen endotracheal tube placement and use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Albuterol DPI (A006) Clinical Study-B2: Efficacy, Dose-Ranging and Initial Safety Evaluation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol DPI 25 mcg/inh|DRUG: Albuterol DPI 90 mcg/inh|DRUG: Placebo DPI|DRUG: Albuterol MDI 90 mcg/inh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ferumoxtran-10-enhanced MRI in Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer|Metastasis|Prostatectomy
Interventions: DRUG: Ferrotran® (Ferumoxtran-10)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Metastatic Tumors of the Urogenital Area With Cytokine-induced Killer Cells
Status: UNKNOWN
Conditions: Bladder Cancer|Renal Cancer
Interventions: BIOLOGICAL: cytokine-induced killer cells|OTHER: Standard treatment according to the Clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic (PK/PD) Study Evaluating DA-3031 (PEG-G-CSF) to Filgrastim (Dong-A) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DA-3031|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Home-Based Walking Program and rTMS in Helping Breast Cancer Survivors Get More Physical Activity
Status: COMPLETED
Conditions: Cancer Survivor|Invasive Breast Carcinoma
Interventions: OTHER: Physical Activity|OTHER: Questionnaire Administration|PROCEDURE: Repetitive Transcranial Magnetic Stimulation|PROCEDURE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Dramatization Simulation on Nursing Students' Ethical Attitudes
Status: COMPLETED
Conditions: ETIC
Interventions: BEHAVIORAL: Dramatization simulation|BEHAVIORAL: In-class case studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula
Status: NOT_YET_RECRUITING
Conditions: Periampullary Cancer|Postoperative Pancreatic Fistula
Interventions: BIOLOGICAL: Intraportal transplantation of isolated autologous pancreatic islets after total pancreatectomy|PROCEDURE: Pancreaticoduodenectomy (classic Whipple or pylorus-preserving)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Nosocomial Infections (CleanKids)
Status: COMPLETED
Conditions: Severe Acute Malnutrition|Health Care Associated Infection|Multi Drug Resistant Organisms
Interventions: OTHER: Health-care associated infection (HCAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Proton Dose Escalation for Patients With Atypical or Anaplastic Meningiomas
Status: NOT_YET_RECRUITING
Conditions: Meningioma
Interventions: RADIATION: Radiotherapy 68 Gy(RBE)|RADIATION: Radiotherapy 72 Gy(RBE)|RADIATION: Radiotherapy 60 Gy(RBE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe)
Status: WITHDRAWN
Conditions: Hearing Loss|Hearing Disorders|Hearing Abnormality|Hearing Disability|Tinnitus
Interventions: DEVICE: HearMe Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Health Literacy and Obesogenic Behaviors
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Adolescent|Health Behavior|Health Knowledge, Attitudes, Practice|Diet, Healthy|Exercise|Health Literacy
Interventions: BEHAVIORAL: Obesity Prevention|BEHAVIORAL: Health Literacy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Less Neurotoxic Drugs in Patients With HAND (MARAND-X)
Status: TERMINATED
Conditions: Hiv|Neurocognitive Dysfunction
Interventions: DRUG: emtricitabine, darunavir/cobicistat, maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline
Status: TERMINATED
Conditions: Post-traumatic Stress Disorder (PTSD)
Interventions: DRUG: Propranolol|DRUG: Prazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intramuscular (IM) Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Agitation
Interventions: DRUG: IM olanzapine|DRUG: IM haloperidol plus lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Pharmacokinetics Study to Assess Safety, Tolerability of Levetiracetam 45 Minutes Intravenous Infusion During 4 Days of Bid Dosing in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DRUG: Levetiracetam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diffusion Tensor Sequences (DTI) for Study of Lumbar Roots by Magnetic Resonance Imaging (MRI)
Status: COMPLETED
Conditions: Radiculopathy Lumbar|MRI|Diffusion Tensor Imaging
Interventions: DIAGNOSTIC_TEST: Optimisation of DTI sequences
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Polarization Sensitive Optical Coherence Tomography (PS-OCT) for Retinal Imaging
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Polarization-Sensitive OFDI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safe and Effective Delivery of Supplemental Iron to Healthy Volunteers
Status: UNKNOWN
Conditions: Iron
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate|DIETARY_SUPPLEMENT: IHAT|DIETARY_SUPPLEMENT: Aspiron|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial
Status: RECRUITING
Conditions: Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation
Interventions: DRUG: ezetimibe/high-intensity statin combination therapy (ezetimibe 10mg plus atoravastatin 40mg)|DRUG: high-intensity statin monotherapy (atoravastatin 40mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Related Factors of Bariatric Surgery on Glomerular Filtration Rate
Status: UNKNOWN
Conditions: Bariatric Surgery|Glomerular Filtration Rate
Interventions: PROCEDURE: sleeve gastrectomy|PROCEDURE: gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sequential vs Upfront Intensified Neoadjuvant Chemotherapy in Patients With Large Resectable or Locally Advanced Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Ponatinib and Nilotinib in Participants With Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Phase Chronic Myeloid Leukemia
Interventions: DRUG: Ponatinib 30 mg QD|DRUG: Ponatinib 15 mg QD|DRUG: Nilotinib 400 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Bioequivalence Of Different Formulations of Opicapone in Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson
Interventions: DRUG: BIA 9-1067 (clinical micronized, CM)|DRUG: BIA 9-1067 (to-be-marketed, TBM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Aerobic Exercise Program in Patients With Moderate-severe Sleep Apnea
Status: TERMINATED
Conditions: Sleep Apnea Hypopnea Syndrome|Physical Activity
Interventions: OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Dexcom G6 Continuous Glucose Monitoring System With a Non-Interferent Sensor
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Acetaminophen Challenge (G6 CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: capivasertib|DRUG: docetaxel|OTHER: placebo|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Tacrolimus (FK506) for Lupus Nephritis: A Placebo Controlled, Double-Blind Multicenter, Comparative Study
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reversal of Ventricular Remodeling With Toprol-XL
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Seloken ZOK/Toprol-XL|DRUG: Seloken ZOK/Toprol-XL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: VIRTUS: An Evaluation of the Vici™ Venous Stent System in Patients With Chronic Iliofemoral Venous Outflow Obstruction
Status: COMPLETED
Conditions: Chronic Venous Disorder|Venous Outflow Obstruction|Symptomatic Venous Outflow Obstruction of Iliofemoral Vein
Interventions: DEVICE: Veniti Vici™ Venous Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma Multiforme
Interventions: RADIATION: Stereotactic hypofractionated RT 5x5Gy|RADIATION: Stereotactic hypofractionated RT 5x7Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT