pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chemoradiotherapy for Patients With Locally Advanced Nasopharyngeal Carcinoma Using Raltitrexed-Cisplatin
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: raltitrexed-cisplatin|RADIATION: Intensity-modulated radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer Recurrent
Interventions: DRUG: Chemotherapy|RADIATION: Preoperative radiotherapy|OTHER: Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orbital Vessel PreparaTIon to MaximIZe Dcb Efficacy in Calcified Below the Knee (BTK) Lesions - A Pilot Study
Status: COMPLETED
Conditions: PAD|Vascular Calcification
Interventions: DEVICE: Peripheral Orbital Atherectomy System|DEVICE: 014 Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Brain Stimulation for the Treatment of Parkinson´s Disease-related Pain
Status: COMPLETED
Conditions: Parkinson Disease|Pain
Interventions: DEVICE: Active Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of ET190L1 ARTEMIS™ in Relapsed, Refractory B Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: BIOLOGICAL: ET190L1 ARTEMIS™ T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant With or Without Tbo-filgrastim in Treating Patients With Multiple Myeloma or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Plasma Cell Myeloma
Interventions: PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Tbo-filgrastim|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Seven-day Combined Rabeprazole Plus Levofloxacin Plus Augmentin for Eradication of Helicobacter Pylori
Status: TERMINATED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Levofloxacin-Amox/clav.|DRUG: Clarithromycin-Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites
Status: TERMINATED
Conditions: Ascites|Decompensated Cirrhosis
Interventions: DRUG: BIV201 continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VISN 23 Chronic Obstructive Pulmonary Disease (COPD) Case Management Using Home Telehealth Equipment
Status: UNKNOWN
Conditions: COPD
Interventions: DEVICE: Use of Telehealth equipment (Viterian V-100)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: CBCT Segmentation in Volumetric Measurements of MS Using Different Soft Wares: A Validity and Reliability Study
Status: UNKNOWN
Conditions: Sinus Volume|CBCT Segmentation
Interventions: DEVICE: semiautomatic software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Feasibility Study of Barrier Enhancement for Eczema Prevention
Status: UNKNOWN
Conditions: Eczema
Interventions: DRUG: Sunflower oil|DRUG: Control group|DRUG: Aquaphor ointment|DRUG: Cetaphil cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Crystalloids or Colloids for Goal-directed Fluid Therapy With Closed-loop Assistance in Major Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Plasmalyte|DRUG: Volulyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety/Tolerability After Oral Administration of CKD-387 and D484 in Healthy Adults
Status: UNKNOWN
Conditions: Type II Diabetes
Interventions: DRUG: CKD-387|DRUG: D484
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver Fibrosis
Status: COMPLETED
Conditions: Liver Fibrosis|Nonalcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis
Interventions: DRUG: BMS-986036|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Smartphone-based Screening Tool for Neonatal Jaundice in a Ugandan Population
Status: TERMINATED
Conditions: Neonatal Jaundice
Interventions: DEVICE: smartphone-based screening tool for neonatal jaundice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Activating Mutation|EGFR DEL19|EGFR L858R
Interventions: OTHER: Plasma ctDNA|OTHER: FFPE blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of PRF Palatal Bandage on Pain Scores and Wound Healing After Free Gingival Graft
Status: COMPLETED
Conditions: Pain|Wound Healing
Interventions: DEVICE: Platelet Rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FLT (PET/CT) in Pediatrics With Myeloproliferative Neoplasms
Status: TERMINATED
Conditions: Essential Thrombocythemia|Primary Myelofibrosis, Fibrotic Stage|Primary Myelofibrosis, Prefibrotic Stage|Polycythemia Vera
Interventions: DEVICE: Diagnostic (18F-FLT PET/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial Testing Professional and Peer-led Support Online Support Groups for Young Canadian Breast Cancer Survivors
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BEHAVIORAL: online support group|BEHAVIORAL: online support group|BEHAVIORAL: home study support materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hear Me Read 2021 Clinical Trial
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Deafness|Hearing Disorders in Children|Hearing Impaired Children|Speech Therapy|Speech Disorders in Children|Literacy
Interventions: BEHAVIORAL: Speech Language Therapy|BEHAVIORAL: Digital Software Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of DHA-O in Adults With Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: DHA-O|DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Outcomes During Rigid Cystoscopy in Females With and Without Cystoscopic Sheath Obturator
Status: TERMINATED
Conditions: Dysuria
Interventions: PROCEDURE: Cystoscopy - with use of obturator sheath|PROCEDURE: Cystoscopy - without use of obturator sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Precede-Proceed Model Based Simulation Experience in Needlestick and Sharps Injuries Among Nurses
Status: COMPLETED
Conditions: Needlestick Injuries
Interventions: BEHAVIORAL: Precede-Proceed Model Based Simulation Experience|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: LY900014|BIOLOGICAL: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Pharmacodynamics and Pharmacokinetics of Biphasic Insulin Aspart 50 to Biphasic Insulin Aspart 70 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)
Status: NOT_YET_RECRUITING
Conditions: Dedifferentiated Liposarcoma
Interventions: DRUG: Pemigatinib|DRUG: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multisite Randomized Controlled Trial of Mindfulness Meditation Therapy for PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Present Centered Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Migraine Treatment With Botulinum Toxin-A: an Investigation of Functional Magnetic Resonance Imaging Changes.
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DRUG: Botulinum Toxin-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trials on Adjuvant Intraperitoneal Chemotherapy for Resectable Local Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: cisplatin, Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Study to Assess DES Re-endothelization in BMS Restenosis and De-novo Lesions
Status: COMPLETED
Conditions: Stable Coronary Artery Disease|Silent Myocardial Ischemia|In-stent(BMS)Restenosis|De-novo, Atherosclerotic, Coronary Lesions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chaplain-Delivered Compassion Meditation to Improve Spiritual Care of Patients Receiving Stem Cell Transplantation
Status: RECRUITING
Conditions: Lymphoma|Multiple Myeloma
Interventions: PROCEDURE: Spiritual Therapy|OTHER: Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Standardized Extract of Cultured Lentinula Edodes Mycelia (AHCC®) in Ovarian Cancer Patients on Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Ovarian Epithelial Carcinoma|Fallopian Tube Carcinoma|Peritoneal Carcinoma
Interventions: DRUG: AHCC|DRUG: Chemotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) Among Young Adults
Status: RECRUITING
Conditions: Social Media Addiction
Interventions: BEHAVIORAL: 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Intense Endocrine Therapy for High Risk and Locally Advanced Prostate Cancer
Status: RECRUITING
Conditions: Neoadjuvant Therapy|High Risk Prostate Cancer|Locally Advanced Prostate Cancer|Intense Endocrine Therapy
Interventions: DRUG: ADT|DRUG: Abiraterone Acetate|DRUG: Prednisolone tablets|DRUG: Enzalutamide|DRUG: Apalutamide|DRUG: Darotamide|DRUG: Rezvilutamide|DRUG: PARP inhibitor|PROCEDURE: Robot-assisted radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department
Status: COMPLETED
Conditions: Acute Migraine Headache
Interventions: DRUG: prochlorperazine and benadryl IV|DRUG: Imitrex SubQ, saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Addition of Amifostine (Ethyol®) to Idarubicin and Cytosine Arabinoside in Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Idarubincin and Amufostine (Ethyol)|DRUG: Idarubincin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Conventional Right hemicolectomy (Non-CME)|PROCEDURE: Right hemicolectomy with CME+CVL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects With Mild Dementia Due to AD (XanADu)
Status: COMPLETED
Conditions: Dementia, Alzheimer Type
Interventions: DRUG: Xanamem™|DRUG: Placebo (for Xanamem™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin in Pediatric FD Population
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Oral Melatonin Supplements in Chronic Kidney Disease (CKD)-Associated Sleep Disorders
Status: UNKNOWN
Conditions: End Stage Renal Disease|Chronic Kidney Disease|Sleep Disorder
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of 48-hour Sevoflurane Inhalation Using a Disposable Delivery System (AnaConDa©) in ICU Patients With Acute Kidney Injury
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Sedation with sevoflurane during 48-hr in ICU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study
Status: TERMINATED
Conditions: Surgical Wound Infection|Cystitis|Bacteremia|Pneumonia|Enterocolitis, Pseudomembranous
Interventions: DRUG: Synbiotic 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of the Diagnostic Detection Rate of Axumin (Fluciclovine) Digital PET/CT, Post-prostatectomy
Status: TERMINATED
Conditions: Prostatic Neoplasm
Interventions: DIAGNOSTIC_TEST: Fluciclovine PET/CT using a digital PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis Externa
Status: COMPLETED
Conditions: Acute Otitis Externa
Interventions: DRUG: AL-60371, 0.3% Otic Suspension|OTHER: AL-60371 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids|Heavy Menstrual Bleeding
Interventions: DRUG: OBE2109|DRUG: Placebo to match OBE2109|DRUG: Placebo to match Add-back|DRUG: Add-back
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Hypericum Perforatum L and Hyaluronic Acid on Excisional Palatal Wound Healing
Status: RECRUITING
Conditions: Wound Healing Disorder|Palate; Wound
Interventions: PROCEDURE: local application of hyaluronic acid agent to the wound site|PROCEDURE: Local application of hypericum perforatum L to the wound site|PROCEDURE: wound healing monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fenretinide|DRUG: Tamoxifen Citrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IV Bioseal Study in Brain Tumor Surgery
Status: COMPLETED
Conditions: Hemostasis|Meningioma Surgery
Interventions: BIOLOGICAL: Bioseal Fibrin Sealant|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab and Trastuzumab in Treating Patients With Metastatic Pancreatic Cancer That Progressed After Previous Treatment With Gemcitabine
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cetuximab|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Advanced Urinary Tract Cancer
Status: COMPLETED
Conditions: Distal Urethral Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation in Post MI LV Thrombus Trial in Nepal
Status: RECRUITING
Conditions: Left Ventricular Thrombus|Myocardial Infarction
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Dengue Virus Vaccine (rDEN4delta30-200,201) in Healthy Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: rDEN4delta30-200,201|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Compare the Progressive Cracking Technique and Conventional Chop Technique on Corneal Endothelial Cells in Patients With Hard Nucleus Cataract
Status: UNKNOWN
Conditions: Hard Nuclear Cataract|Corneal Endothelial Cell|Progressive Cracking Technique
Interventions: PROCEDURE: Progressive Cracking Technique|PROCEDURE: Conventional Chop Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of ASP8232 in Subjects With Renal Impairment and in Type 2 Diabetes Mellitus Subjects With Chronic Kidney Disease
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP8232|Pharmacodynamics of ASP8232|Chronic Kidney Disease (CKD)|Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: ASP8232|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: PF-06650833|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%
Status: UNKNOWN
Conditions: Prehypertension
Interventions: DIETARY_SUPPLEMENT: Mizkan rice vinegar with acetic acid|DIETARY_SUPPLEMENT: Mizkan rice vinegar without acetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Natural History of Community-Associated MRSA Infections and Decolonization Strategies
Status: COMPLETED
Conditions: Abscesses|Furunculosis|Staphylococcus Aureus|Staphylococcal Skin Infections
Interventions: DRUG: Mupirocin ointment|GENETIC: Chlorhexidine showers|PROCEDURE: Bleach baths (dilute)|BEHAVIORAL: Intensive education on personal hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection of 99mTc-nanocolloid and ICG to Identify, Retrieve and Qualify TDLN in Early-stage NSCLC
Status: RECRUITING
Conditions: Early-stage Lung Cancer
Interventions: RADIATION: 99mTc-nanocolloid|DRUG: ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stage III Community-based Efficacy Trial for Mothering From the Inside Out
Status: COMPLETED
Conditions: Addiction|Substance Abuse Drug Chronic|Child Neglect|Child Neglect Emotional|Child Abuse|Parenting|Parent-Child Problem|Parent-Child Relations|Parent / Child Problem|Parenteral Drug Abuse|Parents
Interventions: BEHAVIORAL: Mothering From the Inside Out (MIO)|BEHAVIORAL: Parent Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Performance-specific Cleft Speech Intervention and Long-term Learning in Children With a Cleft Palate
Status: RECRUITING
Conditions: Cleft Palate Children|Speech Disorders in Children|Cleft Lip and Palate|Speech Therapy
Interventions: BEHAVIORAL: Motor-phonetic intervention|BEHAVIORAL: Phonological intervention|BEHAVIORAL: Combined phonetic-phonological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lessons on Urethral Lidocaine in Urodynamics
Status: COMPLETED
Conditions: Urethra Issue|Pelvic Organ Prolapse|Urinary Incontinence|Vaginal Vault Prolapse|Cystocele|Uterine Prolapse|Vaginal Prolapse|Pelvic Floor Disorders
Interventions: DRUG: Water-Based Vaginal Lubricant|DRUG: lidocaine topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Telerehabilitation-Based Early Upper Extremity Training in Stroke Patients
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: control + working group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 90% Effective Dose of Metaraminol in Supine and Left Tilt Positions on Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Metaraminol 2.7μg/kg/min|DRUG: Metaraminol 2μg/kg/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Burden of Influenza-related Hospitalizations and Emergency Room (ER) Visits in Children in Spain
Status: COMPLETED
Conditions: Influenza
Interventions: PROCEDURE: Throat swab and/or nasopharyngeal swab|OTHER: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound-guided vs. Blinded Dry Needling for Piriformis Syndrome
Status: NOT_YET_RECRUITING
Conditions: Piriformis Syndrome
Interventions: PROCEDURE: Ultrasound-guided dry needling|PROCEDURE: Blinded dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Isotretinoin and Temozolomide in Adults With Recurrent Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Anaplastic Glioma
Interventions: DRUG: Vorinostat|DRUG: Isotretinoin|PROCEDURE: Surgical Resection|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of KX2-391 in Elderly Subjects With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: KX2-391
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Berry Consumption on Indicators of Cardiovascular Disease Risk
Status: COMPLETED
Conditions: Blood Pressure|Platelet Function|Inflammation
Interventions: OTHER: berry products|OTHER: control products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of [123I] AV83 and SPECT in Patients With Alzheimer Disease in Comparison to Healthy Controls
Status: COMPLETED
Conditions: Alzheimers Disease
Interventions: RADIATION: [123-I] AV-83 Injection and Imaging Procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Which Technique is More Effective for People With Hamstring Tightness in Terms of Balance, Flexibility, and Performance?
Status: COMPLETED
Conditions: Sports Physical Therapy|Musculoskeletal Diseases or Conditions
Interventions: DEVICE: Percussion Massage Therapy|DEVICE: Graston|OTHER: Dynamic Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Applying Ujjayi Pranayama on Cortisol in Lupus Patients
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Ujjayi pranayama
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Transtheoretical Model Based Nutrition Education on Sustainable Nutrition Behavior in Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: BEHAVIORAL: Sustainable nutrition education based on the transtheoretical model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial to "Study the Efficacy and Therapeutic Safety of Ivermectin: (SAINTBO)
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hypertension in Young Adults Trial
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: Anti-hypertensive agent: amlodipine|DRUG: Anti-hypertensive agent: Chlorthalidone|DRUG: Anti-hypertensive agent: Losartan|DEVICE: Home BP monitoring with cuffed device|DEVICE: Home BP monitoring with cuffed device + BP patch|DEVICE: Home BP monitoring with cuffed device + BP watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Improvement With Olmesartan Medoxomil Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: olmesartan medoxomil + hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure|DRUG: atenolol+ hydrochlorothiazide + amlodipine + hydralazine if necessary to control blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Differing Financial Incentive Structures for Increasing Antidepressant Adherence Among Adults
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Financial incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgesic Efficacy of Fascia Iliaca Compartment Block
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Bupivacaine|DRUG: Dexamethasone/bupivacaine|DRUG: Magnesium Sulfate/bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CSD201201: Study to Assess Elements of Abuse Liability for Electronic Nicotine Delivery System P12
Status: COMPLETED
Conditions: Smoking|Smoking Behaviors|Tobacco Use|Tobacco Smoking
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D|OTHER: Product E|OTHER: Product N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Contrast Agent on Endothelial Function in Healthy Men
Status: COMPLETED
Conditions: Contrast Agent|Endothelial Function|Cytokines|Apoptosis of Endothelial Progenitor Cell|Free Radical|Alpha-lipoic Acid
Interventions: OTHER: Contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pharmacokinetic Study to Assess Dose Proportionality, Safety and Tolerability of Diazepam Nasal Spray in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: diazepam nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Assessment of Morphometric, Functional, Biomechanical and Biological Interactions Between Atherosclerotic Plaque and Platelets Within the Stenosed Coronary Artery
Status: RECRUITING
Conditions: Chronic Coronary Syndrome|Atherosclerosis
Interventions: DIAGNOSTIC_TEST: OCT examination|DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Assessment of vFFR and shear stress parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|EphA2 Overexpression|KRAS G12V|KRAS G12C|KRAS G12D
Interventions: BIOLOGICAL: KRAS-EphA-2-CAR-DC|DRUG: Abraxane|DRUG: Cyclophosphamide|DRUG: Anti-PD-1 antibody|DRUG: Anti-CTLA4 Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Enhanced Recovery After Surgery on Clinical and Immune Outcomes for Gynecological Oncology
Status: UNKNOWN
Conditions: Gynecologic Cancer
Interventions: PROCEDURE: ERAS procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulating Movement Intention Via Cortical Stimulation
Status: RECRUITING
Conditions: Seizures|Seizure Disorder|Psychogenic Movement Disorder
Interventions: DEVICE: Sham TMS3 stimulation|DEVICE: rTMS of left or right angular gyrus (AG) or frontal cortex (FC)|DEVICE: Anodal tDCS of left or right AG or FC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of Induction-Maintenance Protocol for Patients With Chronic Myelogenous Leukaemia
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia|Philadelphia Chromosome Positive CML
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumonia|Diarrhea|Malaria|Co-infection|Death|Malnutrition
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AZD6738, DNA Damage Repair/Novel Anti-cancer Agent, in Combination With Paclitaxel, in Refractory Cancer
Status: COMPLETED
Conditions: Refractory Cancer
Interventions: DRUG: AZD6738|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing AM001 Cream to Vehicle in the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis|Skin Diseases, Papulosquamous|Skin Diseases
Interventions: DRUG: AM001 Cream, 7.5%|DRUG: Placebo of AM001 Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Dysbiosis in Preschool Children With Asthma: Predictive of a Severe Form
Status: RECRUITING
Conditions: Asthma in Children|Dysbiosis
Interventions: PROCEDURE: Stool test|PROCEDURE: Blood test|PROCEDURE: Induced sputum|PROCEDURE: nasale virology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Intravesical Botulinum Toxin in TC-3 Gel in OAB Patients
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: DEVICE: BTX mixed with TC-3 Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular Melanoma
Status: COMPLETED
Conditions: Ocular Melanoma
Interventions: DRUG: Sorafenib|DEVICE: Radioembolization with SIR-Spheres® (Yttrium Microspheres)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of Hydration by Isotonic Solution in the Prevent of the Fainting Whole Blood Donors
Status: COMPLETED
Conditions: Fainting|Presyncope|Syncopal Episode
Interventions: OTHER: tensing exercises|OTHER: No tensing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock
Status: COMPLETED
Conditions: Severe Sepsis or Septic Shock in Pediatric Intensive Care Unit
Interventions: PROCEDURE: Mini-bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Jing Si Herbal Tea on Quality of Life and Sleep in Dementia and Their Caregivers
Status: NOT_YET_RECRUITING
Conditions: Dementia|Caregiver Burden|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Jing Si Herbal Tea|DIETARY_SUPPLEMENT: Barley Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia.
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia|Right Ventricular Dysfunction|In the Perinatal Period
Interventions: OTHER: Echo scans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3
Status: COMPLETED
Conditions: Bleeding Hemorrhoids
Interventions: DRUG: PP110 Gel|DRUG: PP110 Medicated wipes|DRUG: Preparation-H Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seasonal Trivalent Inactivated Split Virion Influenza Vaccine Clinical Trial (IVACFLU-S) - PHASE 2/3
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: IVACFLU-S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
Status: NOT_YET_RECRUITING
Conditions: Healthy|Healthy Nutrition
Interventions: DIETARY_SUPPLEMENT: B. infantis|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study Of Bazedoxifene/Conjugated Estrogen Tablets In Postmenopausal Women
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: bazedoxifene/conjugated estrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monochromatic Phototherapy on Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Monochromatic phototherapy, Biolight®|DEVICE: Monochromatic phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a DNA HIV Vaccine (VRC-HIVDNA009-00-VP) in HIV Infected Individuals With Acute HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA009-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Smell in Covid-19 and Efficacy of Nasal Theophylline
Status: COMPLETED
Conditions: Covid19|Anosmia|Olfactory Disorder|Covid-19 Pandemic|SARS-CoV-2 Infection|Hyposmia|Ageusia|Hypogeusia
Interventions: DRUG: Theophylline Powder|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Preoperative Fasting on ECG and Vital Parameters
Status: COMPLETED
Conditions: Fasting|Intraoperative Complications|Ischemia
Interventions: OTHER: Preoperative Fasting for 8 hours|OTHER: Preoperative Fasting for more than 12 hours|DRUG: Spinal Anesthesia with Bupivacaine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Virtual Rotor Mapping and Catheter Ablation
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: physician's personal experience|PROCEDURE: Virtual rotor mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor in Severe Community Acquired Pneumonia
Status: TERMINATED
Conditions: Community Acquired Pneumonia, Severe
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Culturally Adapted CBT Based Guided Self-Help in Patients With Postnatal Depression
Status: COMPLETED
Conditions: Postnatal Depression
Interventions: OTHER: CaCBT based guided self help using Khushi aur Khatoon Manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pneumatic Retinopexy Versus Vitrectomy With Gas for Retinal Detachment Due to Myopic Macular Hole
Status: COMPLETED
Conditions: Retinal Detachment
Interventions: PROCEDURE: Pneumatic Retinopexy|PROCEDURE: Vitrectomy with Gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: the Effect of coenzymeq10/Collagen Hydrogel on Bone Regeneration in Extraction Socket
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Negative control group|PROCEDURE: Postive control|PROCEDURE: Study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foley Catheter for Labor Induction in Women With Term and Near Term Membrane Rupture
Status: TERMINATED
Conditions: Fetal Membranes, Premature Rupture|Labor, Induced/IS
Interventions: DEVICE: Transcervical Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LAM Pilot Study With Imatinib Mesylate
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: Imatinib Mesylate 400Mg Capsule|DRUG: Placebo - Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
Status: RECRUITING
Conditions: Obesity|Vasodilation|Healthy
Interventions: DRUG: Propranolol Hydrochloride|DRUG: Isoproterenol|DRUG: Phentolamine Mesylate|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Investigate Safety, Tolerability and Distribution of CHF 6333 After One or After Repeated Inhalation in Patients With Cystic Fibrosis (CF) and in Patients With Non Cystic Fibrosis (NCFB) Bronchiectasis
Status: COMPLETED
Conditions: Cystic Fibrosis|Non-Cystic Fibrosis Bronchiectasis
Interventions: DRUG: CHF 6333|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Coronary Angioplasty for de Novo Lesions in sMall vesSElS With Drug Eluting Balloon.
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Drug elluting Balloon (DEB)|DEVICE: Drug elluting coronary stent (DES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels
Status: COMPLETED
Conditions: Nutritional Requirements
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: selenium as L-selenomethionine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopic, Contact Force and Local Impedance With Ultra-high Density Mapping Guided Radiofrequency Ablation Comparison for cavoTricuspid Isthmus dependenT Atrial fluttER: the FLUTTER Study
Status: WITHDRAWN
Conditions: Typical Atrial Flutter
Interventions: DEVICE: Fluoroscopically guided ablation|DEVICE: Contact force guided ablation|DEVICE: Local impedance guide ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT