pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: FRI a Method of Reading Cardiotocography (CTG) in Labor
Status: NOT_YET_RECRUITING
Conditions: Labor Complication
Interventions: OTHER: Interpretation of the CTG using FRI score|OTHER: Classic interpretation of the CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventive Effects of Aspirin as Adjuvant Therapy in Patients With Locally Advanced Renal Cell Carcinoma
Status: RECRUITING
Conditions: Aspirin as Adjuvant Therapy in Patients With Surgically Treated High Risk Renal Cell Carcinoma
Interventions: DRUG: Low dose of aspirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Confocal Laser Endomicroscopy Findings in Patients With Proctosigmoiditis Before and After Initiation of Treatment
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DEVICE: Confocal laser endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Interpretation Bias as a Mechanism of Treatment Response in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive bias modification for interpretation bias|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perinatal Depression and Adverse Childhood Experiences: Prevention Trial
Status: RECRUITING
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of PD1 / PDL1 Expression on Blood Cells & Tumor Tissue, Their Role as a Prognostic Target in NSCLC Patients
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: Evaluation of PD-1/PDL-1 expression.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cetuximab+Zimberelimab in Combination With Cisplatin and Nab-paclitaxel in Resctable Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hend and Neck Squamous Cell Carcinoma Locally Advanced Operable
Interventions: DRUG: Cetuximab|DRUG: Zimberelimab|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy
Status: COMPLETED
Conditions: Post-operative Surgical Pain
Interventions: PROCEDURE: Nerve Block with ropivicaine 0.5% Injectable Solution|PROCEDURE: Nerve Block with Placebo sham control of 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia|Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone|DRUG: Chronocort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Fasitibant- low dose|DRUG: Fasitibant- intermediate dose|DRUG: Fasitibant- high dose|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety And Tolerability Of Meningococcal B Rlp2086 Vaccine In Healthy Adults
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: rLP2086 vaccine or control|BIOLOGICAL: rLP2086 vaccine or control|BIOLOGICAL: rLP2086 vaccine or control|BIOLOGICAL: rLP2086 vaccine or control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Riluzole in Women With Stage I, Stage II, or Stage IIIA Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: riluzole|GENETIC: polymorphism analysis|PROCEDURE: axillary lymph node biopsy|PROCEDURE: digital image analysis|PROCEDURE: needle biopsy|PROCEDURE: sentinel lymph node biopsy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen
Status: RECRUITING
Conditions: Postmenopausal Depression|Estrogen
Interventions: DRUG: Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs|DRUG: SSRIs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin/Metformin FDC|DRUG: Linagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TARGET BP I Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Dehydrated alcohol|DEVICE: Peregrine System Kit (Sham Procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Motor Lateralization as Handwriting Intervention in School-Based OT
Status: COMPLETED
Conditions: Developmental Dysgraphia
Interventions: BEHAVIORAL: SML|BEHAVIORAL: CON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Hyperuricemia|Abnormal Renal Function
Interventions: DRUG: Febuxostat|DRUG: Benzbromarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Lower Limb Spasticity in Multiple Sclerosis Patients
Status: SUSPENDED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Transcranial magnetic stimulation|OTHER: Conventional exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Neuropathology|Cognitive Decline|Sleep Disorder
Interventions: PROCEDURE: Polysomnography|BEHAVIORAL: Neuropsychological assessment|BEHAVIORAL: Questionnaires on sleep and behavioural problems|PROCEDURE: Actimetrics|OTHER: Biomarker assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Inflammatory Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|DRUG: tipifarnib|BIOLOGICAL: filgrastim|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Evaluation of Inflabloc Cap in the Treatment of Patients With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Dehydroepiandrosterone [DHEA]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Huaier Granule on the Treatment of Idiopathic Membranous Nephropathy
Status: RECRUITING
Conditions: Nephropathy|Glomerular Diseases|Idiopathic Membranous Nephropathy
Interventions: DRUG: Huaier granule|DRUG: Renin-angiotensin-aldosterone system inhibitors (RASI)|DRUG: Ciclosporin soft capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Status: RECRUITING
Conditions: Depressive Symptoms|Depression|Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Dose-finding Study of Adjuvanted SCB-2020S Vaccine in Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Candidate vaccine, SCB-2020S|BIOLOGICAL: Candidate vaccine, SCB-2019|OTHER: Squalene based adjuvant|OTHER: CpG/alum adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-myeloablative Allogeneic Transplantation for the Treatment of Multiple Myeloma
Status: COMPLETED
Conditions: Blood Cancer|Multiple Myeloma
Interventions: PROCEDURE: Autologous hematopoietic cell transplant (Auto-HCT)|PROCEDURE: Allogeneic hematopoietic cell transplant (Allo-HCT)|DRUG: Cyclophosphamide|DRUG: Filgrastim|DRUG: Melphalan|RADIATION: Total body irradiation (TBI)|PROCEDURE: Cyclosporine (CSP)|DRUG: Mycophenolate Mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Duramesh™ on Hernia Formation After Ileostomy Closure, Randomized Controlled Trial
Status: RECRUITING
Conditions: Incisional Hernia|Ileostomy - Stoma
Interventions: DEVICE: duramesh|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary Bypass: a Prospective Observational Study
Status: UNKNOWN
Conditions: Hearing Loss|Cardiac Surgery|Cardiopulmonary Bypass|Postoperative Cognitive Dysfunction|Delirium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of High Intensity Circuit Training on Physical Fitness, Body Fat Percentage and Waist-Hip Ratio Among Sedentary Females of Sikandarabad
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: High Intensity Circuit Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Neurotoxicity
Interventions: DRUG: calcium gluconate|DRUG: magnesium sulfate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zanubrutinib-based Induction and Maintenance Therapy in Young and Fit Patients With Untreated Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: R-CHOP/R-DHAOx； Zanubrutib（induction）； ASCT conditioning ； Zanubrutinib（Maintenance）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat
Status: COMPLETED
Conditions: Cholestasis
Interventions: DRUG: Linerixibat tablet|DRUG: [14C]-linerixibat intravenous infusion|DRUG: Linerixibat oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality to Reduce Pre-Operative Anxiety
Status: SUSPENDED
Conditions: Virtual Reality|Augmented Reality|IV Stick|Mask Induction|Ambulatory Surgery|Pain|Anxiety
Interventions: DEVICE: Oculus Go VR|DEVICE: Mira Prism VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn More About Copanlisib Treatment Patterns in People With Indolent Non-Hodgkin Lymphoma, a Type of Cancer That Grows and Spread Slowly and Develops in the Lymphatic System (a Part of Immune System) in Taiwan Under Real-word Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: Copanlisib (BAY80-6946)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma
Status: UNKNOWN
Conditions: MGMT-Unmethylated Glioblastoma
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study on Three Formulations of Curcumin With Different Carriers
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MAG fish oil + Curcumin OR Rice bran oil + Curcumin OR Curcumin extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WEANING-Study: "Weaning by Early Versus lAte Tracheostomy iN supratentorIal iNtracerebral Bleedings
Status: TERMINATED
Conditions: Intracerebral Hemorrhage
Interventions: PROCEDURE: Early tracheostomy|PROCEDURE: Late tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: Oropharyngeal Cancer|Carcinoma
Interventions: DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sutent Following Chemotherapy, Radiation and Surgery For Resectable Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin|PROCEDURE: Radiation|PROCEDURE: Surgery|DRUG: sunitinib (Sutent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Santyl|OTHER: White Petrolatum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Adenocarcinoma of the Stomach|Squamous Cell Carcinoma of the Esophagus|Stage II Esophageal Cancer|Stage II Gastric Cancer|Stage III Esophageal Cancer|Stage III Gastric Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: oxaliplatin|DRUG: fluorouracil|RADIATION: radiation therapy|PROCEDURE: conventional surgery|OTHER: immunohistochemistry staining method|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|PROCEDURE: laboratory biomarker analysis|GENETIC: gene expression analysis|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-436 for Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Abuse|Alcohol Use Disorders|Alcoholism
Interventions: DRUG: ABT-436|DRUG: Matched Placebo - Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Safety and Immunogenicity Study of GPNV-001
Status: RECRUITING
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Gamma-PN3|BIOLOGICAL: Pneumovax-23|BIOLOGICAL: Prevenar-13|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Oral Trigonella Foenum-graecum Seed Extract Vs Placebo in Treatment of None Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Trigonella Foenum-graecum Seed Extract|DRUG: Drug: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Epratuzumab in Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Epratuzumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin Plus Cetuximab for Treatment of Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Carboplatin|BIOLOGICAL: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship of the Medial Longitudinal Arch Height With Clinical Features of Knee Osteoarthritis
Status: COMPLETED
Conditions: Foot Deformities|Pes Planus|Pes Cavus|Knee Osteoarthritis|Knee Pain Chronic|Disability Physical|Lower Limb Deformity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Irritation That Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene Gel|DRUG: Tretinoin Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Folliculotropic Mycosis Fungoides|Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides|Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Mycosis Fungoides|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified|Sezary Syndrome|Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Sternal Closure System (TALON)
Status: COMPLETED
Conditions: Sternal Wound Infection|Mediastinitis
Interventions: DEVICE: Rapid Sternal Closure System|DEVICE: Conventional wire closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of AC2993 With or Without Immunosuppression on Beta Cell Function in Patients With Type I Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: AC2993 (exenatide)|DRUG: daclizumab (immunosuppressive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dislocation Precautions
Status: UNKNOWN
Conditions: Arthroplasty, Hip Replacement|Arthroplasties, Hip Replacement|Health-Related Quality Of Life
Interventions: PROCEDURE: Posterior Approach Precautions|PROCEDURE: Anterior Approach Precautions|PROCEDURE: No Precautions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: UV1|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|Breast Conserving Surgery|Mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Airway Clearance in Bronchiectasis: is Non-Invasive Ventilation a Useful Adjunct in Moderate to Severe Disease?
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DEVICE: NIV and ACBT|OTHER: Active Cycle of Breathing Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Surgical Strategies for Robotic Implantation of Total Knee Prostheses (Stryker), Cemented Versus Uncemented
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Knee prosthesis implementation with additional cement|DEVICE: Knee prosthesis implementation without additional cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol Treatment of the Borderline Significant PDA
Status: UNKNOWN
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Paracetamol drops|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmote SUpport for Low-Carbohydrate Treatment of Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus in Obese
Interventions: BEHAVIORAL: Low Carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Sustained Release Fluocinolone Implant for Treatment of Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: DEVICE: fluocinolone acetonide (Retisert Implant, Bausch and Lomb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Whole-food, Plant-Based Diet|BEHAVIORAL: General Nutritional Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Versus Invasive Blood Pressure Measurement in the Morbidly Obese Parturient With Severe Preeclampsia
Status: TERMINATED
Conditions: Pre-Eclampsia|Morbid Obesity|Parturient|Blood Pressure
Interventions: DEVICE: Non-invasive BP recording with conical Ultracheck Curve BP cuff|DEVICE: Non-invasive BP recording with traditional cylindrical BP cuff|OTHER: Direct invasive arterial pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnosis of Adenomyosis Using Ultrasound, Elastography and MRI
Status: COMPLETED
Conditions: Endometriosis|Adenomyosis
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: transvaginal ultrasound|DIAGNOSTIC_TEST: transvaginal ultrasound elastography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: PROCEDURE: TACE|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Darolutamide (ODM-201) in Men With High-risk Non-metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Non-Metastatic|Castration-Resistant
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Treatment Access and Recovery in COD
Status: RECRUITING
Conditions: Opioid Use Disorder|Mental Health Disorder
Interventions: OTHER: Medication for Opioid Use Disorder|BEHAVIORAL: MISSION Critical Time Intervention|BEHAVIORAL: MISSION Peer Support|BEHAVIORAL: MISSION Dual Recovery Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Status: RECRUITING
Conditions: SPINAL Fracture|Burst Fracture|Spinal Instability of Thoracolumbar Region
Interventions: PROCEDURE: Surgical stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice
Status: UNKNOWN
Conditions: Gynecological Pathology
Interventions: DRUG: Lidocaine-Prilocaine cream|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of Treatment and Management of Schizophrenia in Europe (OPTIMISE): Substudy Site Copenhagen
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: DRUG: Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Oral Care With Glutamine on Oral Health, Oral Flora and Incidence of Pneumonia After Neurosurgery With Microbiome Analysis
Status: RECRUITING
Conditions: Oral Mucositis|Pneumonia
Interventions: DRUG: Glutamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Changes of Ryodoraku and HRV After PPI Treatment in GERD Patients
Status: UNKNOWN
Conditions: Non-erosive Reflux Disease|Barrett's Esophagus
Interventions: DEVICE: Ryodoraku|DEVICE: ANSWatch|DEVICE: UGI endoscopy|OTHER: GerdQ|DRUG: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Neurodinamic Techniques on Radial Nerve for the Treatment of Lateral Epicondylalgia
Status: NOT_YET_RECRUITING
Conditions: Lateral Epicondylitis \(Tennis Elbow\)
Interventions: OTHER: neural tensioning technique on radial nerve|OTHER: Sliding technique on radial nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Bronchitis|Emphysema|Asthma-COPD Overlap Syndrome
Interventions: OTHER: E-Cigarette|BEHAVIORAL: Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: FDL169|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Diarrhea Predominant Irritable Bowel Syndrome
Interventions: DRUG: Multi-strain probiotics|DRUG: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Young Houston Emergency Opioid Engagement System
Status: RECRUITING
Conditions: Opioid-use Disorder|Opioid Dependence|Opioid Overdose|Opioid Use|Substance Use Disorders
Interventions: DRUG: Buprenorphine, Naloxone Drug Combination|BEHAVIORAL: Individual Counseling|BEHAVIORAL: Peer Recovery Support Services|BEHAVIORAL: Support Group|BEHAVIORAL: Referral to Medication Management|BEHAVIORAL: Assertive Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X: New Insights Into the Pathophysiology
Status: COMPLETED
Conditions: Syndrome X|Takotsubo Cardiomyopathy
Interventions: OTHER: BaroReflex Sensitivity, endothelial function measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Alteration of Temporal Organization of EEG Microstate Sequences During Propofol-induced Loss of Consciousness
Status: COMPLETED
Conditions: Loss of Consciousness
Interventions: DEVICE: Target Controlled Infusion system (Orchestra Base Primea, Fresenius, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of GB491 in Combination With Letrozole in Patients With HR Positive and HER2 Negative Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: GB491 combined with Letrozole|DRUG: Placebo combined with Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capillary Versus Suction Needle Aspiration for Endobronchial Ultrasound (EBUS) Biopsies.
Status: COMPLETED
Conditions: Lung Cancer|Mediastinal Lymphadenopathy|Thoracic Cancer
Interventions: PROCEDURE: Endobronchial Ultrasound guided Transbronchial Fine Needle Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Potential Benefit of r-hLH Addition in Patients Aged 35 to 40 Under Ovarian Stimulation Treatment
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: DRUG: Recombinant Human Follitropin Alfa Solution for Injection (Gonal-f®)|DRUG: Recombinant Human Lutropin alfa for Injection (r-hLH, Luveris®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy, Safety, and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Vaccine GSK1437173A
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes Zoster vaccine GSK1437173A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Is There a Worse Outcome When the Systolic Blood Pressure is Lower Than Heart Rate in Those Adult Trauma Patients With Isolated Head/Neck Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: OTHER: reversed shock index < 1|OTHER: reversed shock index ≥ 1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate the Effects of Different Doses of S-adenosyl-L-methionine (SAMe) in Subjects With Nonalcoholic Fatty Liver Disease and Non-treated Matched Healthy Volunteers as Control Group
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DRUG: SAMe 1000 mg|DRUG: SAMe 1500 mg|DRUG: SAMe 2000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2624803 in Japanese Participants With Transient Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: LY2624803 - Solution|DRUG: LY2624803 - Capsule|DRUG: Placebo - Solution|DRUG: Placebo - Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Use of Air Cleaners to Mitigate Cardiopulmonary Health Impact of Indoor Exposure to Particles and Phthalates
Status: COMPLETED
Conditions: Blood Pressure|Lung Function|Inflammation|Oxidative Stress
Interventions: BEHAVIORAL: Air cleaner use method 1|BEHAVIORAL: Air cleaner use method 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prediction of Postoperative Acute Kidney Injury in Patients With Acute Type A Aortic Dissection Using Cystatin C
Status: COMPLETED
Conditions: Aortic Dissection|Acute Kidney Injury
Interventions: OTHER: postoperative acute kidney injury|OTHER: none postoperative acute kidney injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus AG Combined With PD-1 Sequential Radiotherapy as First-line Treatment of Locally Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Locally Advanced Pancreatic Cancer
Interventions: DRUG: nal-IRI+Oxaliplatin+5-FU/LV+PD-1|DRUG: Gemcitabine + albumin-paclitaxel+PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine to Treat Adolescents With Coexisting Alcohol and Other Substance Use Disorder and ADHD
Status: COMPLETED
Conditions: Substance Use Disorders|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Menopause|Plaque|Inflammation
Interventions: OTHER: scaling and root planing (srp)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telehealth Mindfulness After Spine Surgery
Status: RECRUITING
Conditions: Lumbar Spine Surgery|Chronic Low-back Pain|Postsurgical Pain
Interventions: BEHAVIORAL: Telehealth mindfulness-based intervention (MBI)|BEHAVIORAL: Telehealth Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soft Active Back Exosuit to Reduce Workplace Back Pain
Status: ENROLLING_BY_INVITATION
Conditions: Low Back Pain|Musculoskeletal Pain|Low Back Injury
Interventions: DEVICE: Back Exosuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Ascending Dose Study of PRX002 in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: PRX002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Water|OTHER: Glucose|OTHER: Fructose|OTHER: Sucrose|OTHER: Sucralose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Escalating Doses of a Novel Viscous Polysaccharide on Postprandial Glycemia
Status: COMPLETED
Conditions: Blood Glucose, Postprandial
Interventions: DIETARY_SUPPLEMENT: PolyGlycopleX (PGX)|DIETARY_SUPPLEMENT: PolyGlycopleX (PG)|DIETARY_SUPPLEMENT: PolyGlycopleX|DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Second Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HEXT (Hypo EXTended): Effect of PTH on Skeleton in Hypoparathyroidism
Status: COMPLETED
Conditions: Hypoparathyroidism
Interventions: DRUG: open-label PTH(1-84)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients.
Status: COMPLETED
Conditions: Endothelial Dysfunction|Endstage Renal Disease
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Mini-Chop Plus Ofatumumab To Treat Cd 20+ Diffuse Large B-Cell Lymphoma In Patients Aged Over 80 Years
Status: COMPLETED
Conditions: Non Previously Treated CD20+ Diffuse Large B-cell Lymphoma
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Treatment Modality in Necrotic Primary Molars
Status: COMPLETED
Conditions: Primary Teeth|Dental Pulp Regeneration
Interventions: OTHER: pulp regeneration for necrotic primary teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Pharmacokinetics of Rilpivirine With Rifabutin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rilpivirine|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients
Status: WITHDRAWN
Conditions: Breast Cancer Stage IV|Ovarian Cancer|BRCA1 Mutation|BRCA2 Mutation
Interventions: DRUG: Carboplatin|DRUG: Eribulin|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER2 TREAT Study: Retrospective Study to Estimate the Prevalence of HER2-low in Unresectable and/or Metastatic Breast Cancer Patients Who Progress on Anti-Cancer Therapy Identified as HER2-Negative From Patient Medical Records in The Gulf Cooperation Council
Status: RECRUITING
Conditions: Breast Neoplasms|Breast Cancer|Breast Carcinoma|Genes|HER2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: AZD4604|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Electrophysiological Predictors of Arrhythmic Recurrence in Patients With Paroxysmal AF Undergoing First Ablation Procedure of AF by Pulmonary Vein Isolation
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal
Interventions: OTHER: Standard of care|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Distinct Sources of Supplementary Protein in the Resistance Exercise Training-induced Adaptations
Status: RECRUITING
Conditions: Dietary Supplements|Muscle Strength|Muscle, Skeletal|Resistance Training|Diet Habit
Interventions: DIETARY_SUPPLEMENT: Animal protein|DIETARY_SUPPLEMENT: Plant Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability Study of CEREBO® - A Novel Non-invasive Intracranial Bleed Detector
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Intracranial Hemorrhages
Interventions: DEVICE: CEREBO®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Caesarean Delivery With or Without an Indwelling Bladder Catheter
Status: UNKNOWN
Conditions: Urinary Tract Infections|Cesarean Section; Infection
Interventions: PROCEDURE: Without placement of indwelling catheter|PROCEDURE: With placement of indwelling catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
Status: UNKNOWN
Conditions: Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
Interventions: DRUG: nefopam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors
Status: COMPLETED
Conditions: Metastatic Cancer|Solid Tumors|Colorectal Cancer (CRC)|Gastric Cancer|Head and Neck Cancer|Lung Cancer|Renal Cell Carcinoma (RCC)|Bladder Cancer|UC (Urothelial Cancer)|Mesothelioma
Interventions: DRUG: INCB001158|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noise Exposure and Near-Infrared Light
Status: COMPLETED
Conditions: Hearing Loss, Noise-Induced
Interventions: DEVICE: Near Infrared Light|OTHER: Noise Stimulus|DEVICE: Sham Near Infrared Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome
Status: TERMINATED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: lidocaine patch 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-monitoring and Adherence of Patients With COPD to Long-term Rehabilitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Pulmonary rehabilitation (PR) plus PA monitoring and feedback from a pedometer|BEHAVIORAL: Pulmonary rehabilitation (PR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 68Ga PSMA-11 PET/CT in Recurrent Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer|Prostate Cancer Metastatic|Prostate Cancer Metastatic to Bone
Interventions: DRUG: 68Ga PSMA-11 injection|PROCEDURE: Positron Emission Tomography/Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Epidemiological Insights Into the Formation, Progression, and Rupture of Intracranial Aneurysms: A Retrospective, Multi-Center Hospital-Based Study in China
Status: RECRUITING
Conditions: Intracranial Aneurysm|Subarachnoid Hemorrhage, Aneurysmal|Cerebral Aneurysm|Brain Aneurysm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post Market Clinical Follow-Up of the Zimmer Stafit Acetabular System
Status: TERMINATED
Conditions: Osteoarthritis, Hip|Fracture of Hip|Avascular Necrosis of Hip|Dislocated Hip|Osteonecrosis|Post-traumatic; Arthrosis|Rheumatoid Arthritis|Subluxation Hip
Interventions: DEVICE: Patients who received the Stafit Acetabular System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Cognitive Enhancement as a Precursor to Computer Based Training for Cognitive Behavioral Therapy (CBT4CBT)
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Treatment As Usual (TAU)|BEHAVIORAL: TAU plus Rapid Abstinence Initiation (RAI)|BEHAVIORAL: TAU plus RAI plus Cognitive Control Training (CCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT