pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Levamisole Supplementation on Tetanus Vaccination Response Rates in Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Dialysis
Interventions: DRUG: Levamisole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction
Status: TERMINATED
Conditions: Intrauterine Growth Restriction (IUGR)|Fetal Growth Restriction (FGR)
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Carboplatin, and Sunitinib in First Line Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: irinotecan|DRUG: Carboplatin|DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Disease|Heart Diseases|Cardiovascular Diseases|Neurologic Manifestations
Interventions: DRUG: Magnesium|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the Universitair Ziekenhuis Brussel During the 2020 COVID-19 Outbreak
Status: UNKNOWN
Conditions: Sars-CoV2
Interventions: DIAGNOSTIC_TEST: Serological testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Effects of UE Aerobic and Resistance Training on Cardiorespiratory Fitness in Hypertensive Patients
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: upper extremity aerobic training|OTHER: upper extremity resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Pentavalent Meningococcal Conjugate Vaccine (EuNmCV-5) in Healthy Adults Aged 19 to 55 Years Old
Status: COMPLETED
Conditions: Infection, Meningococcal
Interventions: BIOLOGICAL: EuNmCV-5|BIOLOGICAL: Menveo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Socket Preservation: A Clinical and Histological Study
Status: COMPLETED
Conditions: Alveolar Ridge Augmentations
Interventions: BIOLOGICAL: BioXclude amnion-chorion membrane|BIOLOGICAL: Mem-Lok collagenous membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Histological Analysis of Osteogenic Potential of Biphasic Calcium Phosphate
Status: COMPLETED
Conditions: Alveolar Ridge Enlargement|Fenestration|Dehiscence
Interventions: PROCEDURE: Bone augmentation with I-BCP|PROCEDURE: Bone augmentation with BX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, Radiation Therapy, and Docetaxel With or Without Cisplatin in Treating Patients With Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: irinotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fortified Cheese and Yogurt Products and Vitamin D Status in Young Children? Phase 2
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cheese & yogurt + Vitamin D|DIETARY_SUPPLEMENT: Cheese & yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination
Status: COMPLETED
Conditions: Papillomavirus Vaccines
Interventions: BEHAVIORAL: Current care|BEHAVIORAL: Reminder-recall|BEHAVIORAL: Audit-and-feedback|BEHAVIORAL: Combined reminder-recall and audit-and-feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Value of PET CT in the Histologic Lymph Node Status of Patients With Squamous Cell Carcinoma of the Oral N0 Clinical and Radiological Cavity.
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Oral|Clinically Node-Negative and Radiology
Interventions: DIAGNOSTIC_TEST: PET-CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I-Ib/II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 Alone and in Combination With Bortezomib, With or Without Dexamethasone, in Patients With Relapsed or Refractory Multiple Myeloma.
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: AUY922|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: High definition transcranial electrical current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Health and Employment After Gastro Intestinal Surgery - HEAGIS1
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasm|Colonic Neoplasms
Interventions: BEHAVIORAL: Promotion of competences of participant involved in the management of the post operative period
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Differentiating Everolimus Versus Sirolimus in Combination With Calcineurin Inhibitors in Kidney Transplant Patients
Status: WITHDRAWN
Conditions: Kidney Transplantation
Interventions: DRUG: Everolimus|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Safety, Tolerability, and Efficacy of AFN-12520000 in the Treatment of Acute Bacterial Skin and Skin Structure Infections Due to Staphylococci
Status: COMPLETED
Conditions: Skin and Subcutaneous Tissue Bacterial Infections|Wound Infection|Cutaneous Abscess|Burn Infection|Cellulitis
Interventions: DRUG: AFN-12520000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Trial for Pain Relief in Schwannomatosis (STARFISH)
Status: RECRUITING
Conditions: Schwannomatosis|Schwannomas|Pain, Chronic
Interventions: DRUG: Siltuximab|DRUG: Erenumab-Aooe|DRUG: Siltuximab Matching Placebo|DRUG: Erenumab-Aooe Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FDGal PET/CT and PET/MRI in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: 18F-FDGal PET/CT or PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)
Status: RECRUITING
Conditions: HIV-Infected Individuals
Interventions: BIOLOGICAL: DD HST-NEETs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Virtual Reality: Helps Reduce Anxiety and Pain During Bronchial Fibroscopies in Lung Transplant Patients.
Status: UNKNOWN
Conditions: Anxiety|Stress|Pain|Bronchial Fibroscopy|Pulmonary Transplantation
Interventions: OTHER: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nalbuphine Versus Fentanyl As Additives To Bupivacaine In Spinal Anaesthesia For Internal FixationI Of Tibia
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Fentanyl/Hyperbaric bupivacaine|DRUG: Nalbuphine/Hyperbaric bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: LVIS™ and LVIS™ Jr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Muscle Relaxation on Cognitive Function in Patients With Mild Cognitive Impairment and Early Stage Dementia.
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Alzheimer Dementia
Interventions: DEVICE: Muscle relaxation using full body massage machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Continuous Positive Airway Pressure (CPAP), Oral Appliance and Physical Exercise in the Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|DEVICE: Oral Appliance (OA)|BEHAVIORAL: Physical Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Management of Argatroban in Patients With Heparin Induced Thrombocytopenia Type II
Status: COMPLETED
Conditions: Heparin-induced Thrombocytopenia Type II
Interventions: DRUG: argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Untreated Salivary Gland Malignant Neoplasms
Status: RECRUITING
Conditions: Salivary Gland Malignant Neoplasms|Salivary Gland Tumors
Interventions: DRUG: Sintilimab , Carboplatin, Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Treatment With SInergy™ System to Conservative Treatment for Chronic Sacroiliac Joint Pain
Status: TERMINATED
Conditions: Chronic Sacroiliac Joint Pain
Interventions: DEVICE: Treatment with SInergy™ System|OTHER: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: BIOLOGICAL: Botulinum toxin type A Dose 1|BIOLOGICAL: Botulinum toxin type A Dose 2|DRUG: Placebo (Normal Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RES Prepared With RECELL® Compared to Conventional Care for Healing of Donor Sites in Ages 1-16 Years
Status: TERMINATED
Conditions: Skin; Deformity
Interventions: DEVICE: RECELL® Autologous Cell Harvesting Device|OTHER: Telfa™ Clear and Xeroform™ dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nasal-spraying LiveSpo Navax in Treatment of Acute Respiratory Infections in Children
Status: COMPLETED
Conditions: Acute Respiratory Tract Infections
Interventions: COMBINATION_PRODUCT: LiveSpo Navax|DRUG: 0.9% NaCl physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cabbage Leaf Wraps in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Cabbage leave wraps|DRUG: Diclofenac Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Serous Tumor|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Berzosertib|DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uterus Transplantation to Treat Infertility
Status: RECRUITING
Conditions: Uterine Factor Infertility
Interventions: PROCEDURE: Uterine Allotransplantation|DRUG: Tacrolimus|DRUG: Imuran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Augmented Reality to Enhance CPAP Therapy in OSA Patients
Status: NOT_YET_RECRUITING
Conditions: Aherence|Physical Symptoms|Mental Health|Quality of Life
Interventions: BEHAVIORAL: With AR guided CPAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Hydro-dissection Versus Ultrasonic Aspirator in Division of Liver Parenchyma in Laparoscopic Resection
Status: COMPLETED
Conditions: Liver Transection During Laparoscopic Liver Resection
Interventions: PROCEDURE: liver transection during laparoscopic liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ethanol on Overnight Glucose Regulation in Type 2
Status: COMPLETED
Conditions: Type 2 Diabetes, Insulin Requiring
Interventions: OTHER: oral ethanol, overnight|OTHER: IV ethanol|OTHER: soda water|OTHER: soda water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Natural Killer Cells Functions, Tumoral Escape to Immune System and Regulation of Natural Cytotoxixity Receptors in Haematological Malignancies
Status: UNKNOWN
Conditions: Leukemia
Interventions: OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: HTEMS Treatment of Diabetic Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy
Interventions: DEVICE: HTEMS|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing COVID-19, Influenza, and Pneumonia Vaccine Uptake
Status: WITHDRAWN
Conditions: Covid19|Influenza|Pneumonia|Vaccine Refusal
Interventions: BEHAVIORAL: Full VEPMP Intervention|BEHAVIORAL: Partial VEPMP Intervention|BEHAVIORAL: Delayed VEPMP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Levocarnitine in Treating Patients With Vismodegib-Associated Muscle Spasms
Status: COMPLETED
Conditions: Musculoskeletal Complications
Interventions: DIETARY_SUPPLEMENT: levocarnitine|OTHER: placebo|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natural Killer Cell (CYNK-001) Infusions in Adults With AML
Status: RECRUITING
Conditions: Leukemia|Leukemia, Myeloid|Leukemia, Myeloid, Acute|Neoplasms by Histologic Type|Neoplasms|Immunosuppressive Agents|Immunologic Factors|Physiological Effects of Drugs|Alkylating Agents|Antimetabolites, Antineoplastic|Antiviral Agents|Analgesics, Non-narcotic|Anti-infective Agents|Analgesics|Peripheral Nervous System Agents|Hematologic Diseases|Hematologic Neoplasms|Leukemia in Remission|Relapsed Adult AML|Refractory AML
Interventions: BIOLOGICAL: CYNK-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin A in Preventing Gastrointestinal GVHD in Participants Undergoing Donor Stem Cell Transplant
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient
Interventions: DIETARY_SUPPLEMENT: Vitamin A Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The First-in-human Study of SRN-001 in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: SRN-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partitioned Training of Patients With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Lung; Disease, Interstitial, With Fibrosis
Interventions: OTHER: intervention -1-leg cycle training|OTHER: usual care - 2-leg cycle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification|Lung Adenocarcinoma Stage IIIB/IV
Interventions: DRUG: Tepotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Use of Tocotrienol From Annatto Bixa Orellana L. in Breast Cancer Patients: a Prospective Clinical Trial.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tocotrienol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of QAW039 When Added to Standard-of-care Asthma Therapy in Patients With Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QAW039|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: High Cholesterol/Hyperlipidemia|High Blood Pressure|Overweight and Obesity
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare Efficacy and Safety of CT-P16 and EU-Approved Avastin as First-Line Treatment for Metastatic or Recurrent Non-Squamous Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Adenocarcinoma of Lung
Interventions: DRUG: CT-16|DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Adding GSK2190915 to Low Dose Inhaled Corticosteroid Treatment for Asthma Subjects > or = 12 Years of Age
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FP 100|DRUG: GSK2190915 100|DRUG: GSK2190915 300|DRUG: montelukast|DRUG: placebo|DRUG: FP/SAL 100/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Video-Enhanced Consent on Informed Decision-Making for Parents of Extremely Preterm Infants Eligible for the ViDES Study
Status: NOT_YET_RECRUITING
Conditions: Understanding of Consent in Clinical Research|Implementation of Video-Consent in Clinical Research
Interventions: OTHER: ViDEO explaining study|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: E7389 Administered as an IV Bolus Infusion Day 1 and Day 8 Every 3 Weeks in Pre-Treated Patients With Advanced and/or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: E7389
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VARC-TAVI VALVE IMPLANTATION)
Status: NOT_YET_RECRUITING
Conditions: Severe Aortic Stenosis|TAVI\(Transcatheter Aortic Valve Implantation\)|Vascular Complications
Interventions: PROCEDURE: Secondary TAVI access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imagery Rescripting in the Treatment of Post Traumatic Stress Disorder (PTSD) Following Early Chronic Interpersonal Trauma
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Imagery Rescripting and Reprocessing Therapy|BEHAVIORAL: STAIR + Imagery Rescripting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II AK Study in Organ Transplant Patients
Status: UNKNOWN
Conditions: Actinic Keratoses|Carcinoma, Squamous Cell|Organ Transplant Recipients
Interventions: DRUG: Afamelanotide (CUV1647)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radioimmunotherapy in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: 90-Y-ibritumomab tiuxetan|BIOLOGICAL: rituximab|RADIATION: indium In 111 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
Status: COMPLETED
Conditions: Cardiogenic Pulmonary Edema
Interventions: DEVICE: hCPAP versus HFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CD7 CAR-T Cell Injection in the Treatment of Patients With Relapsed or Refractory CD7-positive Peripheral T Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: CAR-T Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FTY720 in Patients With Uveitis
Status: WITHDRAWN
Conditions: Acute Noninfectious Posterior, Intermediate, or Pan Uveitis
Interventions: DRUG: FTY720|DRUG: Oral Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Specialized Nutraceutical for Pre-burnout
Status: COMPLETED
Conditions: Burn Out|Psychological Disturbance
Interventions: DIETARY_SUPPLEMENT: Meta 18.06 Day and Meta 18.06 Night|DIETARY_SUPPLEMENT: Placebo Meta 18.06 Day and Placebo Meta 18.06 Night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Observe the Safety and Efficacy of ScTIL210 in the Treatment of Malignant Solid Tumors
Status: RECRUITING
Conditions: Malignant Solid Tumor
Interventions: BIOLOGICAL: Super circulating tumor infiltrating lymphocytes(ScTIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Tolerability and Feasibility of Oral Sulfate Solution (SUPREP) in Hospitalized Patients
Status: UNKNOWN
Conditions: Inpatient Colonoscopy|Oral Sulfate Solution|Polyethelene Glycol
Interventions: DRUG: SUPREP Bowel Prep Kit|DRUG: Golytely Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Pregnant Women With OUD
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Collaborative Care (CC)|BEHAVIORAL: Extension for Community Healthcare Outcomes (ECHO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tucatinib (ONT-380) Combined With Capecitabine and/or Trastuzumab in Patients With HER2+ Metastatic Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Metastatic Breast Cancers
Interventions: DRUG: Tucatinib|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical and Intravenous Administration of TXA Are Equally Effective in DAA THA
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DRUG: 1.5g intravenous Exacyl|DRUG: 3.0g intra-articular Exacyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Trial Investigating the Pharmacokinetics and Pharmacodynamics of rFVIIa in Patients With Haemophilia A or B With or Without Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia A With Inhibitors|Haemophilia B|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)|DRUG: eptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled Insulin (AERx® iDMS) on Blood Glucose Control in Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: pioglitazone|DRUG: inhaled human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Blind, Placebo-controlled Study of Raloxifene for Negative Symptoms of Schizophrenia in Postmenopausal Women
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dispatcher-Assisted CPR: Low-Dose, High-Frequency Simulation-Based Training
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: BEHAVIORAL: Low-Dose, High-Frequency Simulation-Based Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia
Status: TERMINATED
Conditions: Anemia|Leukemia|Acute Myeloid Leukemia (AML)|Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Whole-Brain RT Combined With Thiotepa Sheath Injection Combined With Systemic Therapy for the Primary Disease in the Treatment of Meningeal Metastases in Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor Leptomeningeal Metastasis
Interventions: DRUG: Intrathecal Injection of Thiotepa+Radiation+Systemic Treatment of Primary Diseases
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Treatment-naive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Hemodiafiltration vs Conventional Hemodialysis in Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: DEVICE: Online Pre-dilution Hemodiafiltration|DEVICE: Conventional Hemodialysis|DEVICE: Online Post-dilution Hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Etomidate on Patient Outcomes After Single Bolus Doses
Status: COMPLETED
Conditions: Sepsis|Trauma
Interventions: DRUG: Etomidate|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: L2 Paravertebral catheter nerve block|PROCEDURE: Continuous Lumbar plexus nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Biotrauma of NMBAs and PP Association During ARDS
Status: RECRUITING
Conditions: Moderate to Severe Acute Respiratory Distress Syndrome
Interventions: DRUG: NMBAs|OTHER: Prone positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Neoplasm
Interventions: DRUG: etoposide phosphate|DRUG: melphalan|DRUG: topotecan|PROCEDURE: Autologous Stem Cell Rescue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis|Post Operative Pain
Interventions: DRUG: Tramadol|DRUG: Naproxen Sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Stress-management and Biofeedback on Craving in Smoking Abstinence: A Pilot Study
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: breathing technique|BEHAVIORAL: behavioral strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose
Status: COMPLETED
Conditions: Hyperglycaemia (Diabetic)
Interventions: DRUG: Insulin|BEHAVIORAL: exercise|DIETARY_SUPPLEMENT: Dietary counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-FNB With ROSE Vs. EUS-FNB Without ROSE
Status: COMPLETED
Conditions: Biopsy, Fine-needle|Pancreatic Neoplasm
Interventions: DIAGNOSTIC_TEST: Rapid on-site evaluation (ROSE)|DIAGNOSTIC_TEST: Histologic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Ability of Ionic Foot Bath (IonCleanse®) to Remove Heavy Metals Through the Feet and Its Potential Impact on Body Burden of Heavy Metals
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: IonCLeanse Footbath
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma|Recurrent Malignant Glioma|Recurrent WHO Grade II Glioma|Recurrent WHO Grade III Glioma
Interventions: BIOLOGICAL: Chlorotoxin (EQ)-CD28-CD3zeta-CD19t-expressing CAR T-lymphocytes (via ICT delivery)|BIOLOGICAL: Chlorotoxin (EQ)-CD28-CD3zeta-CD19t-expressing CAR T-lymphocytes (via ICT/ICV dual delivery)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Wuhan) in Patients With Hypertension and/or Diabetes
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: BIOLOGICAL: COVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aneurysm Embolization System for Intracranial Aneurysms
Status: NOT_YET_RECRUITING
Conditions: Ruptured Cerebral Aneurysm
Interventions: PROCEDURE: Implant an aneurysm embolization system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Studies of Oliceridine Fumarate
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: DRUG: Oliceridine Fumarate|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Immunonutrition in Patients Undergoing Gynecologic or General Elective Surgery (PURPOSE)
Status: COMPLETED
Conditions: Surgical Site Infection|Post-Op Complication
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement INergy-FLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fasting Conditions.
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: S1001 PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|OTHER: R-CHOP regimen|OTHER: laboratory biomarker analysis|RADIATION: fludeoxyglucose F 18|RADIATION: selective external radiation therapy|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Activation in Multiple System Atrophy and Parkinson Disease: a Positron Emission Tomography (PET) Study
Status: COMPLETED
Conditions: Multisystemic Atrophy
Interventions: RADIATION: H215O PET|DRUG: Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Longitudinal Assessment of Tumor Evolution in Patients With Brain Cancer
Status: COMPLETED
Conditions: Newly Diagnosed High Grade Glioma
Interventions: DRUG: Temozolomide|RADIATION: conformal brain radiation therapy|DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Bevacizumab|DRUG: 5-day Temozolomide|DRUG: 5-day Temozolomide|DRUG: Lomustine|DRUG: Nivolumab monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Connectome for Acupuncture-treated Migraine Patients
Status: RECRUITING
Conditions: Migraine Without Aura|Acupuncture Therapy
Interventions: OTHER: Real acupuncture|OTHER: Sham acupuncture (placebo group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Platinum-based Chemoradiation Therapy for Locally Advanced Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Cisplatin|DRUG: Carboplatin|RADIATION: Radiation therapy|PROCEDURE: Mastectomy (recommended but not mandatory)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: methylprednisolone|DRUG: Methyl Prednisolonate|DEVICE: ventilators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib in Multiple Myeloma Relapsed After High-dose Melphalan With Autologous Stem Cell Support
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Induction with CAR-CY-DEX and conditioning with carfilzomib and highdose melphalan|DRUG: Carfilzomib/dexamethasone maintenance|DRUG: Observation without carfilzomib/dexamethasone maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Minimization in Kidney Transplant Recipients Selected According to the AGORA Algorithm for Their Low Immunological Risk and Medium-term Graft Failure
Status: NOT_YET_RECRUITING
Conditions: Organ Grafts
Interventions: DRUG: TACROLIMUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Patients With BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: OTHER: Placebo|DRUG: GV1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Renal Safety of Intravenous Ibandronate (Bondronat) in Participants With Metastatic Bone Disease Due to Breast Cancer
Status: COMPLETED
Conditions: Pain; Bone Neoplasms; Neoplasm Metastasis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Stroke|Hemiparesis
Interventions: DEVICE: NMES device with EMG-triggered and Cyclic capabilities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention INC: An Interactive Family-centered mHealth Tool to Reduce Obesity Risk in Urban Minority Preadolescents
Status: NOT_YET_RECRUITING
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Web-based comic and newsletters|BEHAVIORAL: Didactic health information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Norwegian Psychomotor Physiotherapy in Patients With Long-lasting Musculoskeletal Pain.
Status: COMPLETED
Conditions: Physical Disability
Interventions: OTHER: Norwegian Psychomotor Physiotherapy|OTHER: Cognitive Patient Education and PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: protective ventilation|BEHAVIORAL: prone position ventilation|DRUG: glucocorticoid therapy|OTHER: restrictive fluid resuscitation|BIOLOGICAL: Thymosin Alpha|DRUG: Muscle relaxant therapy|OTHER: Integrated Chinese and Western Medicine Treatment|DRUG: statin therapy|COMBINATION_PRODUCT: anti-infective treatment|DEVICE: Extracorporeal Membrane Oxygenation（ECMO）|GENETIC: stem cell therapy|DRUG: Sedative analgesia/muscle relaxant therapy|DRUG: inotropes therapy|DRUG: Vasoactive drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Nitazoxanide and Atazanavir/Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Nitazoxanide|DRUG: Atazanavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Warm Application to the Breast With the Aid of Thera Pearl on Milk Release and Breastfeeding Success
Status: NOT_YET_RECRUITING
Conditions: Breast Feeding
Interventions: OTHER: Thera Pearl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shared Decision Making in Paediatric Inflammatory Bowel Disease
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|IBD
Interventions: OTHER: Decision Coach Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin B Complex and Folic Acid|DIETARY_SUPPLEMENT: Iron and Folic Acid|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Nutritional Benefits of Metanx in Patients With Diabetic Peripheral Neuropathy (MEDIAN)
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathy|B Vitamin Deficiency
Interventions: OTHER: Metanx|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Computerized Cognitive Training Improve Executive Functioning in the Older Adult?
Status: UNKNOWN
Conditions: Cognitive Impairment, Mild|Executive Dysfunction
Interventions: OTHER: RehaCom Computerized Cognitive Training for 480 minutes|OTHER: Pencil-and-Paper Cognitive Training for 480 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effisayil™ 1: A Study to Test Spesolimab (BI 655130) in Patients With a Flare-up of a Skin Disease Called Generalized Pustular Psoriasis
Status: COMPLETED
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of a Caffeine-based Antifibrosis Cream in Patients With Breast Cancer Undergoing Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma Breast
Interventions: DRUG: Caffeine anhydrous 5% added to Lipoderm Cream Base.|OTHER: Lipoderm Cream Base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real World Study on Erlotinib/Gefitinib Combined With Bevacizumab in Advanced Non-aquamous Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Erlotinib/Gefitinib combined with Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Haplo-identical Natural Killer (NK) Cells to Prevent Post-Transplant Relapse in AML and MDS (NK-REALM)
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndromes (MDS)
Interventions: BIOLOGICAL: K-NK002|PROCEDURE: Conditioning Regimen|PROCEDURE: HaploBMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT