pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ventilator Settings for Bronchoscopy During Mechanical Ventilation: a Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation Complication|Fiberoptic Bronchoscopy|Critical Illness|Acute Respiratory Failure
Interventions: OTHER: specific ventilator settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Asthma Exacerbation-induced Changes in Lung Function With a Home-based Spirometer
Status: COMPLETED
Conditions: Asthma|Asthma Attack|Asthma, Allergic
Interventions: DEVICE: Spirobank Smart spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Podiatry Care on Onychomycosis (EPOCAON)
Status: WITHDRAWN
Conditions: Onychomycosis
Interventions: PROCEDURE: Nail lacquer plus aggressive debridement|PROCEDURE: Nail lacquer alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Compare Biosimilar Denosumab With Prolia®
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: BIOLOGICAL: ENZ215|BIOLOGICAL: Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability and Bioavailability of Dasiglucagon Following Subcutaneous (SC) Compared to IV Administration
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Dasiglucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Allogeneic Human UC-MSC and Liberation Therapy (When Associated With CCSVI) in Patients With RRMS
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Allogeneic Human Umbilical Cord Tissue-Derived Mesenchymal Stem Cells|OTHER: Liberation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Precision TACE (P-TACE) With Surefire
Status: WITHDRAWN
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DEVICE: SureFire Infusion System|DEVICE: Standard Endhole Microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Optic Nerve|Neuritis
Interventions: DRUG: Nerispirdine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography - Computed Tomography (PET-CT) Scanning in Chronic Graft Versus Host Disease (cGvHD)
Status: TERMINATED
Conditions: Chronic Graft Versus Host Disease
Interventions: OTHER: PET-CT Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study To Evaluate The Effect Of Rifampicin Or Ltraconazole On Pharmacokinetics Of Ensartinib In Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Ensartinib|DRUG: Rifampicin|DRUG: Itraconazole|DRUG: Ensartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Periodontal Therapy on the Gut Microbiome of Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Periodontal Diseases|IBD|Dysbiosis|Inflammation
Interventions: PROCEDURE: Full mouth scaling and root planing (FMSRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Traditional Chinese Medicine on the Gut Microbiota-dependent Trimethylamine N-oxide
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Compound Panax Notoginseng Granule|DRUG: Placebo Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality in Aphasia Rehabilitation
Status: COMPLETED
Conditions: Stroke, Ischemic|Aphasia
Interventions: OTHER: Cue-based speech therapy in virtual reality|OTHER: Cue-based speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Silent Atrial Fibrillation aFter Ischemic StrOke
Status: COMPLETED
Conditions: Ischemic Stroke|Cerebral Infarction|Brain Ischemia|Brain Infarction|Cerebrovascular Disorders|Brain Disease|Central Nervous System Diseases|Nervous System Diseases|Cardiac Arrhythmias
Interventions: DEVICE: Reveal LINQTM- LNQ11 Internal Loop Recorder plus standard cardiac monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Efficacy of MK0773 in Healthy Postmenopausal Women (0773-003)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: MK 0773|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulpotomy Versus Pulpectomy in Vital Primary Incisors
Status: COMPLETED
Conditions: Dental Caries|Pulp Disease, Dental
Interventions: PROCEDURE: pulpotomy technique with formocresol|PROCEDURE: pulpectomy technique with zinc oxide and eugenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REVAXIS® Versus DT Polio® as a Second Booster in 6 Year-old Children
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Poliomyelitis
Interventions: BIOLOGICAL: REVAXIS®|BIOLOGICAL: DT-Polio®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Progressive Resistance Training for the Improvement of Physical Function
Status: COMPLETED
Conditions: Sarcoma
Interventions: OTHER: Exercise Counseling|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Nivolumab Following Chemo-Radiation in Localized Muscle-Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Evaluation of Myocardial Stiffness by Elastography in Pediatric Cardiology (Elasto-Pédiatrie)
Status: COMPLETED
Conditions: Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy
Interventions: DEVICE: Echography|DEVICE: Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapies for Salivary Flux Stimulation in Patients Transplanted With Hematopoietic Stem Cells
Status: WITHDRAWN
Conditions: Mucositis
Interventions: DEVICE: mechanical stimulation (Elastomers)|PROCEDURE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Visual Surround Suppression and Perceptual Expectation Under Psilocybin
Status: TERMINATED
Conditions: Perception Disturbance|Visual Suppression|Psychedelic Experiences
Interventions: DRUG: Psilocybin|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MaxSimil® fish oil + CoQ10|DIETARY_SUPPLEMENT: Rice bran oil + CoQ10|DIETARY_SUPPLEMENT: CoQ10 as powder form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traveler's Diarrhea (TD) Vaccine Asia Efficacy Study
Status: COMPLETED
Conditions: Traveler's Diarrhea
Interventions: BIOLOGICAL: TD Vaccine System|BIOLOGICAL: TD Vaccine System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Dextromethorphan|Healthy Adult Volunteers
Interventions: DRUG: Isavuconazole|DRUG: dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Minocycline on Cytokine Levels in Severe Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DRUG: oral minocycline hydrochloride treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: nab-sirolimus (also known as ABI-009, nab-rapamycin, albumin-bound rapamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, PD and PK Study in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Open-label TRV734 125 mg|DRUG: TRV734 blinded|DRUG: Oxycodone IR 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiology of Orthostatic Intolerance
Status: RECRUITING
Conditions: Tachycardia|Postural Orthostatic Tachycardia Syndrome
Interventions: RADIATION: DAXOR|PROCEDURE: QSweat|DRUG: Intrinsic Heart Rate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dynamic Ventilatory and Asymmetry of the Chest Wall During Breath Stacking and Volume-oriented Incentive Spirometer
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Breath Stacking|OTHER: Incentive Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying REsponders and Exploring Mechanisms of ACTION of the Endobronchial Coil Treatment for Emphysema
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: RePneu Lung Volume Reduction Coil System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism
Status: COMPLETED
Conditions: Astigmatism|Presbyopia
Interventions: DEVICE: comfilcon A|DEVICE: Samfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Bunion
Interventions: DRUG: COV155|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia
Status: UNKNOWN
Conditions: Pneumonia, Viral|Pneumonia, Ventilator-Associated
Interventions: BIOLOGICAL: UC-MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Pharmacokinetics (PK) of Depemokimab When Delivered With a Safety Syringe Device (SSD) or an Autoinjector in Healthy Adult Participants
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Depemokimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Occupational Therapy in Promoting Medication Adherence
Status: COMPLETED
Conditions: Hypertension|Diabete Type 2
Interventions: BEHAVIORAL: Treatment as Usual Plus Occupational Therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the Safety and Performance of Model 690AD and Model 690ADY Monofocal Intraocular Lens Implantation
Status: COMPLETED
Conditions: Cataract|Pseudophakia|Intraocular Lens Complication|Intraocular Lens Opacification
Interventions: OTHER: Standard of care|OTHER: Patient satisfaction questionnare
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study for Bepotastine Besilate Ophthalmic Solution in Normal Volunteers
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Bepreve|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.
Status: COMPLETED
Conditions: Cocaine Dependence|Opioid Dependence
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Yunnan Baiyao on Minor Recurrent Aphthous Stomatitis
Status: COMPLETED
Conditions: Recurrent Aphthous Stomatitis
Interventions: DRUG: Yunnan Baiyao toothpaste|DRUG: Placebo toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mid-term Data Collection of the Treatment of Intracranial Aneurysms With the WEB™ Aneurysm Embolization System
Status: TERMINATED
Conditions: Ruptured and Unruptured Intracranial Aneurysms
Interventions: DEVICE: WEB aneurysm embolization system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Apatinib Combined With Abraxane and Carboplatin or Cisplatinum as First-line Treatment for Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Apatinib Mesylate|DRUG: Abraxane|DRUG: Cis Platinum|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Predictors Of Response To Mepolizumab In CRSwNP
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Mepolizumab 100 MG Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Letrozole Pretreatment With Misoprostol for First-Trimester Medical Abortion
Status: COMPLETED
Conditions: Complete Miscarriage
Interventions: DRUG: Letrozole|DRUG: Misoprostol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establishment of Precise Nutrition Management Scheme for Patients With Prediabetes Based on Nutrigenomics
Status: RECRUITING
Conditions: Prediabetes
Interventions: BEHAVIORAL: Precise nutritional intervention|BEHAVIORAL: Conventional nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation Versus Sham in Subacromial Pain Syndrome
Status: RECRUITING
Conditions: Subacromial Pain Syndrome|Transcranial Direct Current Stimulation
Interventions: DEVICE: Experimental Stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broadband Amplification as Tinnitus Treatment
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DEVICE: Broadband amplification from hearing aids|DEVICE: Band-limited amplification from hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
Status: RECRUITING
Conditions: Vocal Cord Dysfunction|Vocal Cord Paralysis|Vocal Cord Paresis|Recurrent Laryngeal Nerve Palsy|Recurrent Laryngeal Nerve Injuries
Interventions: DIAGNOSTIC_TEST: Point-of-Care Ultrasound of the Airway
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Cantharidin in Molluscum Contagiosum
Status: COMPLETED
Conditions: Molluscum Contagiosum, Skin Disease
Interventions: DRUG: cantharidin's vehicle|DRUG: Cantharidin 0.7%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium
Status: RECRUITING
Conditions: Pterygium
Interventions: DRUG: CBT-001|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Scanning and Transillumination vs Conventional Examination to Assess Caries Progression, Stability or Regression
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DEVICE: Intraoral Scanner (TRIOS 4, 3Shape TRIOS A/S, Copenhagen, Denmark)|DEVICE: Intraoral camera (DIAGNOcam, KaVo, Biberach, Germany, software version 3.0.1/2.9.1)|DEVICE: X-ray device (X-ray device SOREDEX, MINRAY®; Image plates VistaScan; Image plate scanner VistaScan Mini View, Dürr Dental)|PROCEDURE: Oral cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: OTHER: Biomarker-based diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Pulmonary Rehabilitation for Hospitalized Patients With Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC
Status: WITHDRAWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Nexium®|DRUG: Esomeprazol (40mg) + Sdium Bicarbonate (721mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Rostafuroxin|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Enhancement of Response to Hepatitis B Vaccine by Lenalidomide in Plasma Cell Dyscrasias
Status: COMPLETED
Conditions: Plasma Cell Disorder
Interventions: DRUG: Lenalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Buspirone for Weak or Absent Esophageal Peristalsis
Status: RECRUITING
Conditions: Dysphagia, Esophageal
Interventions: DRUG: Buspirone Hydrochloride 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib (Tarceva) After Surgery With or Without Adjuvant Chemotherapy in Non-Small Cell Lung Carcinoma (NSCLC) Patients Who Have Epidermal Growth Factor Receptor (EGFR) Positive Tumors
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing Water vs. Air Method for Performing Colonoscopy in Adult Female Subjects
Status: COMPLETED
Conditions: Screening for Colon Cancer
Interventions: PROCEDURE: to infuse water into colon to open the lumen for water infusion colonoscopy|PROCEDURE: Air colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Gemcitabine and Erlotinib|DIETARY_SUPPLEMENT: Intravenous Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Woodsmoke on Vascular Function
Status: COMPLETED
Conditions: Vascular Function
Interventions: PROCEDURE: Forearm Vascular Study|PROCEDURE: Badimon Chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Site Prospective, Non-randomized Study of Partial Breast Intracavitary Brachytherapy Devices to Evaluate Local Tumor Control, Cosmetic Outcome and Toxicities.
Status: UNKNOWN
Conditions: This Study Has Been Designed to Compile Information on the Efficacy of the Partial Breast Intracavitary Brachytherapy in the Post Market Setting.
Interventions: OTHER: Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin
Status: COMPLETED
Conditions: CYP2C19 Poor|Extensive Metabolizers
Interventions: DRUG: Rosuvastatin Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rapid Molecular Diagnosis and Detection of Emerging Infectious Diseases in Patients With Tropical Fever (Tropifever)
Status: NOT_YET_RECRUITING
Conditions: Infectious Diseases in Febrile Patients Returning From Tropical Countries
Interventions: DIAGNOSTIC_TEST: Diagnosis algorithm according to the delay between travel and consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Metastatic Non-squamous Non Small Cell Lung Cancer
Interventions: DRUG: CBP501 + Cisplatin + Pemetrexed|DRUG: Cisplatin + Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of PI3K Inhibitor Copanlisib in Combination With Fulvestrant in Selected ER+ and/or PR+ Cancers With PI3K (PIK3CA, PIK3R1) and/or PTEN Alterations
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: Copanlisib|DRUG: fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring and Testing of Blood Pressure in Postpartum Women
Status: RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Remote Blood Pressure Cuff|DEVICE: Blood Pressure (BP) monitoring smart phone app, BabyScripts™|BEHAVIORAL: Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reversal of Acute β-Blocker Induced Bronchoconstriction
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Hydrocortisone/ Placebo and Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Pre Transplant Exercise (Pre-habilitation) for Multiple Myeloma Patients Awaiting Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Myeloma
Interventions: OTHER: Supervised Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abacavir, Dolutegravir and Lamivudine Dispersible Tablets (60 mg/5 mg/30 mg)
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: COMBINATION_PRODUCT: abacavir, dolutegravir and lamivudine dispersible tablets|COMBINATION_PRODUCT: Triumeq Dispersible Tablets 5 mg GSK1349572 [Dolutegravir]/ 60 mg Abacavir/ 30 mg Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aging Program Project Grant 6
Status: RECRUITING
Conditions: Improving Cardiometabolic Outcomes in Older Adults
Interventions: DIETARY_SUPPLEMENT: Melatonin 1 mg|DIETARY_SUPPLEMENT: Placebos|OTHER: Meal timing|OTHER: Non-Meal timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antioxidant Therapy in RYR1-Related Congenital Myopathy
Status: COMPLETED
Conditions: Neuromuscular Disease
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zilver PTX Drug-Eluting Peripheral Stent Study
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Longer Zilver PTX Stents|DEVICE: Shorter Zilver PTX Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Way Crossover Closed Loop Study Insulin vs Insulin and Pramlintide
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DEVICE: MPC closed-loop system in insulin only mode|DEVICE: MPC closed-loop system in insulin/pramlintide mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Exploratory Efficacy of Nimacimab in Patients With Diabetic Gastroparesis
Status: UNKNOWN
Conditions: Diabetic Gastroparesis
Interventions: DRUG: Nimacimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases That Progressed on the Docetaxel and Placebo Group of MDA-ID-030008
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Different Methods of Anxiety Care in Pediatric Settings
Status: WITHDRAWN
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Cognitive Behavior Therapy-Primary Care|BEHAVIORAL: Therapist-Assisted Bibliotherapy-Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-cutting Laser Therapy in the Treatment of Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: V-Beam laser, Candela Corp., 595 nm wavelength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo and in Vitro Anabolic Potential of Essential Amino Acids Following Resistance Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Interventional
Interventions: DIETARY_SUPPLEMENT: Di-Leucine Supplement|DIETARY_SUPPLEMENT: BCAA Supplement|DIETARY_SUPPLEMENT: Collagen Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
Status: RECRUITING
Conditions: Neurodevelopmental Disorders|Intellectual Disability|Development Delay|ADHD|Autism Spectrum Disorder|Epilepsy
Interventions: DRUG: Sulfonylurea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy and Safety of a Simplified Procedure for the Percutaneous Closure of the Patent Foramen Ovale
Status: ACTIVE_NOT_RECRUITING
Conditions: Patent Foramen Ovale
Interventions: OTHER: Patent Foramen Ovale closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Tibial Nerve Stimulation for Patients With Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Percutaneous tibial nerve stimulation (pTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-laryngeal Implant for Treatment of Chronic Aspirations
Status: WITHDRAWN
Conditions: Aspiration Pneumonia|Tracheostomy Complication
Interventions: DEVICE: NewBreez LD intra-laryngeal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Socket Preservation Using the Ice Cream Cone Technique Versus Spontaneous Healing in Fresh Extraction Sockets.
Status: UNKNOWN
Conditions: Socket Preservation
Interventions: PROCEDURE: Ice Cream Cone Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Montelukast Sodium in the Prevention of Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Premature Birth|Infant, Very Low Birth Weight|Bronchopulmonary Dysplasia
Interventions: DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Screening to Augment Referral to Treatment- Project START
Status: COMPLETED
Conditions: Alcohol Abuse|Tobacco Use Disorder|Marijuana Abuse|Substance-Related Disorders
Interventions: BEHAVIORAL: Motivational Interview|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Protection in Post COVID-19 Patients With Sulodexide
Status: COMPLETED
Conditions: Post COVID-19|Endothelial Dysfunction|Thrombosis
Interventions: DRUG: Sulodexide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: graft-versus-tumor induction therapy|BIOLOGICAL: rituximab|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Low dose AUT00206 800mg|DRUG: High dose AUT00206 2000 mg|DRUG: Placebo|DRUG: Ketamine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liberal Versus Restrictive Transfusion Threshold in Oncologic surgerY
Status: COMPLETED
Conditions: Oncologic Complications|Anemia
Interventions: OTHER: Haemoglobin 9.5 g/dL|OTHER: Haemoglobine 7.5g/dL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter|Myocardial Injury After Non-Cardiac Surgery
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer and a Negative PSMA PET
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Fluciclovine PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
Status: COMPLETED
Conditions: Neonatal Resuscitation|Heart Rate Assessment
Interventions: OTHER: Auscultation plus NeoTapAS|OTHER: Auscultation without NeoTapAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Radical colectomy|PROCEDURE: HIPEC|DRUG: Systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine Combined With Chidamide in the Treatment of Newly Diagnosed PTCL Unfit for Conventional Chemotherapy
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Azacitidine|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Varicella-Zoster Virus (VZV) Vaccine to Prevent Shingles in HIV-Infected Children Who Have Already Had Chickenpox
Status: COMPLETED
Conditions: HIV Infections|Chickenpox
Interventions: BIOLOGICAL: Varicella Virus Vaccine (Live)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evolution of Post-Stroke Shoulder Pain With a Capsular Pattern With Physiotherapy Alone Versus Coupled With Mild Arthrographic Distension With Cortisone
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain
Interventions: OTHER: Physiotherapy alone|DRUG: Glenohumeral injection of 40mg (1cc) of Triamcinolone and 7cc of 0.5% Bupivacaine coupled with physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferritin and Iron Burden in SAH sIRB
Status: RECRUITING
Conditions: SAH|Dementia
Interventions: DRUG: Deferiprone pill|DRUG: placebo|BEHAVIORAL: Montreal Cognitive Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Virtual Reality Based Exercises in Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: OTHER: virtual reality based exercises|OTHER: conventional physical therapy|OTHER: home exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Graft Versus Host Disease|Hematopoietic and Lymphoid System Neoplasm
Interventions: DRUG: Cholestyramine|DRUG: Leflunomide|DRUG: Steroid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Removal With CVVHD Compared to CVVH
Status: COMPLETED
Conditions: Cytokine Release Syndrome|Sepsis|AKI
Interventions: PROCEDURE: CVVHD|PROCEDURE: CVVH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dual Site Left Ventricular (LV) Pacing
Status: TERMINATED
Conditions: Congestive Heart Failure|LV Dysfunction
Interventions: DEVICE: Dual Site LV Pacing|DEVICE: BiV Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Flexibility With a Mindbody Approach
Status: COMPLETED
Conditions: General Low Back Hip and Hamstring Flexibility
Interventions: BEHAVIORAL: Neuro Emotional Technique|OTHER: Stretching Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Daglutril Compared to Placebo on Top of Losartan in Type 2 Diabetics With Overt Nephropathy and Well Controlled Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Daglutril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cranberry Ingestion on Bacterial Adhesion: An Adjunct Study
Status: COMPLETED
Conditions: Asymptomatic Bacteriuria
Interventions: DIETARY_SUPPLEMENT: Cranberry Juice|DIETARY_SUPPLEMENT: De-Activated Cranberry juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: BEHAVIORAL: Physical activity|BEHAVIORAL: Sleep hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Treatment of Squamous Cell Carcinoma or Adenocarcinoma of the Cervix With CIGB-300 for Local Application
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Cervix|Adenocarcinoma of the Cervix
Interventions: DRUG: CIGB300
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Participants With Knee Osteoarthrosis
Status: COMPLETED
Conditions: Knee Osteoarthrosis
Interventions: OTHER: Platelet-Rich Plasma|OTHER: Isometric Contractions of Quadriceps|OTHER: Platelet-Rich Plasma Combined with Isometric Contractions of Quadriceps|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma
Status: COMPLETED
Conditions: PTSD|Stress Disorders, Post - Traumatic|Anxiety Disorders|Mental Disorders|Stress Disorders, Traumatic
Interventions: BEHAVIORAL: PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Profile Of Methylation and Gene Expression Of Gene ADRB3 And Effects Of Folate Intake
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Folate and capsule of oil hazel|DIETARY_SUPPLEMENT: Folate and placebo|DIETARY_SUPPLEMENT: antioxidant and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Microbial Colonisation On Vacuum-Formed Retainers Constructed On Conventional Models And Three Dimensional (3D) Reconstructed Models
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: Conventional VFR|DEVICE: VFR from SLA|DEVICE: VFR from FDM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatitis C Virus Self-testing (HCVST) in Sexual and Gender Minorities in Rio de Janeiro
Status: NOT_YET_RECRUITING
Conditions: Hepatitis C
Interventions: DIAGNOSTIC_TEST: Hepatitis C virus self-test (oral fluid HCVST)|DIAGNOSTIC_TEST: Hepatitis C virus self-test (blood-based HCVST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Block-out Spacer to Pick up Locator Attachments to Retain Overdenture: Peri-implant and Alveolar Bone Changes
Status: COMPLETED
Conditions: Bone Loss
Interventions: PROCEDURE: Surgical placement of dental implants|DEVICE: Overdenture supported by locator attachment system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Alemtuzumab Combination With CHOP to Treat Patients Newly Diagnosed With PTCL
Status: TERMINATED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Avatrombopag in the Treatment of Thrombocytopenia After Haplo-HSCT
Status: NOT_YET_RECRUITING
Conditions: Thrombocytopenia|Stem Cell Transplant Complications
Interventions: DRUG: avatrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of YY-20394 in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed or Refractory Peripheral T-Cell Lymphoma
Interventions: DRUG: YY-20394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Apatinib and Capecitabine Combination to Maintain Treating Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: "Apatinib" and "Capecitabine"|DRUG: "Capecitabine"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT