pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma|High Grade B-Cell Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Rituximab|DRUG: Etoposide|DRUG: Vincristine Sulfate|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: Doxorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery
Status: UNKNOWN
Conditions: Mitral Valve Regurgitation|Left Atrium Dilatation and Hypertrophy|Mitochondrial Dysfunction in the Heart|Cardiomyocyte Apoptosis|Cardiac Inflammation
Interventions: DRUG: Lovaza group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Study of CS-1008 for Subjects With Untreated and Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: CS-1008 (humanized anti-DR5 antibody)|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Acupuncture on Vascular and Functional Neuroimaging in Parkinson's Disease Patients With Sleep Disorders
Status: COMPLETED
Conditions: Acupuncture|Parkinson's Disease|Sleep Disorders|Neuroimaging
Interventions: DEVICE: Sterile acupuncture needles for single use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Muscle Stimulation in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Self Stimulation|Exercise Addiction
Interventions: PROCEDURE: NMES|PROCEDURE: Closed Kinetic Chain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Fascial Release Injection for Myofascial Pain Syndrome in the Upper Trapezius Muscle
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: PROCEDURE: Sham injection|PROCEDURE: Fascia injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: of Myo-inositol, Melatonin and Co-enzyme q10 on Ovarian Reserve
Status: NOT_YET_RECRUITING
Conditions: IVF
Interventions: DRUG: Myoinositol|DRUG: Co-Enzyme Q10|DRUG: Melatonin|DRUG: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MESNA Injection for TMJ Internal Derangement
Status: COMPLETED
Conditions: TMJ Disorder
Interventions: DRUG: Mesna Injection|DRUG: Arthrocentesis with ringer solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxone Nasal Spray Pharmacokinetic Study
Status: UNKNOWN
Conditions: Opioid Overdose
Interventions: DRUG: MVP005|DRUG: MVP005|DRUG: Naloxone hydrochloride solution for injection with mucosal atomization device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19|Venous Thromboembolism
Interventions: DRUG: Dimolegin|DRUG: Clexane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Post-Adoption Family Intervention Using Trust-Based Relational Intervention (TBRI) to Improve Understanding, Well-Being, and Connection in Adoptive Families
Status: COMPLETED
Conditions: Family Relations|Parenting
Interventions: BEHAVIORAL: The Connected Family Series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of NLR, TLR, and ALC in Predicting ToF Primary Repair Outcome
Status: COMPLETED
Conditions: Congenital Heart Disease|Tetralogy of Fallot|Neutrophil-lymphocyte Ratio|Absolute Lymphocyte Count|Thrombocyte-lymphocyte Ratio|Outcome|TOF
Interventions: PROCEDURE: ToF primary repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique in Individuals With Asymptomatic Dynamic Knee Valgus
Status: COMPLETED
Conditions: Dynamic Knee Valgus|Force Production|Frontal Plan Projection Angle|Instrument-assisted Soft Tissue Mobilization|Postural Stability
Interventions: DEVICE: Graston Technique®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Hemay005 in Patients With Active Ulcerative Colitis
Status: RECRUITING
Conditions: Moderate to Severe Ulcerative Colitis
Interventions: DRUG: Hemay005 tablets|DRUG: Hemay005 placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Before Prostatectomy and Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Alvocidib in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia|Contiguous Stage II Small Lymphocytic Lymphoma|Noncontiguous Stage II Small Lymphocytic Lymphoma|Stage I Chronic Lymphocytic Leukemia|Stage I Small Lymphocytic Lymphoma|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage III Small Lymphocytic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Small Lymphocytic Lymphoma
Interventions: DRUG: alvocidib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Brain Stem Neoplasm|Pineal Region Neoplasm|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Primary Central Nervous System Neoplasm|Recurrent Visual Pathway Glioma|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Primary Central Nervous System Neoplasm|Refractory Visual Pathway Glioma
Interventions: DRUG: Entinostat|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shortened vs Standard Chemotherapy Combined With Immunotherapy for the Initial Treatment of Patients With High Tumor Burden Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Immunochemotherapy regimen: Rituximab-bendamustine (Arm A)|DRUG: Immunochemotherapy regimen: Rituximab-bendamustine (Arm B)|DRUG: Immunochemotherapy regimen: R-CHOP (Arm A)|DRUG: Immunochemotherapy regimen: R-CHOP (Arm B)|DRUG: Immunochemotherapy regimen: G-bendamustine (Arm A)|DRUG: Immunochemotherapy regimen: G-bendamustine (Arm B)|DRUG: Immunochemotherapy regimen: G-CHOP (Arm A)|DRUG: Immunochemotherapy regimen: G-CHOP (Arm B)|DRUG: Immunochemotherapy regimen: G-CVP (Arm A)|DRUG: Immunochemotherapy regimen: G-CVP (Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cyst|EUS-FNA
Interventions: DRUG: Ethanol|DRUG: Normal saline|DRUG: Paclitaxel + Gemcitabine admixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mentored Community Gardening for Individuals With Skin Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Cancer Survivorship|Skin Cancer|Basal Cell Carcinoma|Squamous Cell Carcinoma|Melanoma (Skin)
Interventions: BEHAVIORAL: Mentored Community Gardening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation
Status: COMPLETED
Conditions: Healthy|Frontotemporal Dementia
Interventions: BIOLOGICAL: AL001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioequivalency Comparing Geneva's 10 mg Glipizide Tablets To Roerig's 10 mg Glucotrol Tablets
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Glipizide 10 mg Tablets (Geneva Pharmaceutical, Inc.)|DRUG: Glucotrol 10 mg Tablets (Roerig Pharmaceutical, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate
Status: COMPLETED
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia|Childhood Acute Lymphoblastic Leukemia in Remission|Recurrent Childhood Acute Lymphoblastic Leukemia|T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supporting Aging Through Green Exercise (SAGE)
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Aging
Interventions: OTHER: Aerobic Exercise Indoors|OTHER: Aerobic Exercise Outdoors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of Chile
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Lansoprazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Step 1 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in ICU Patients
Status: COMPLETED
Conditions: Mechanically Ventilated Patients
Interventions: DRUG: Remimazolam besylate|DRUG: Remimazolam besylate|DRUG: Remimazolam besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: New Topical Treatment for Continued Pain After Shingles
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Epikeia coatings with aspirin|DRUG: Epikeia coatings with lidocaine|OTHER: Epikeia coatings alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-prandial Glycemic Response to Fiber in Healthy Adults
Status: COMPLETED
Conditions: Glucose, High Blood|Glucose, Low Blood|Meals
Interventions: OTHER: resistant starch (high fiber muffin top)|OTHER: control (low fiber muffin top)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vascular Effects of Carvedilol Versus Metoprolol in Hypertensive Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Hypertension|Type 2 Diabetes Mellitus
Interventions: DRUG: Carvedilol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tumor Resection and Gliadel® Wafers, Followed by Temodar® With Standard Radiation or GammaKnife® for New GBM
Status: TERMINATED
Conditions: Glioblastoma
Interventions: PROCEDURE: Gross total resection and Gliadel(R) wafers implanted|RADIATION: GammaKnife(R) stereotactic Radiosurgery|RADIATION: Standard fractionated radiation therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SimCare: Physician Intervention to Improve Diabetes Care
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Simulated case-based customized learning|BEHAVIORAL: Simulated case based customized learning + leader feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trans-vaginal Aspiration of Small Ovarian Endometrioma. Comparison of Two Different Techniques Before ICSI
Status: UNKNOWN
Conditions: Ovarian Endometrioma
Interventions: PROCEDURE: Transvaginal aspiration|PROCEDURE: transvaginal aspiration and surgicel injection|DRUG: Intracytoplasmic sperm injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: cARdiotoxicity Profile of aBIraTeRone in prostAte Cancer : a pharmacoviGilancE Study
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation and Flutter|Tachycardia, Supraventricular|Cardiac Failure
Interventions: DRUG: L02 (sex hormones used in treatment of neoplastic diseases) and G03 (sex hormones)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sipuleucel-T as Neoadjuvant Treatment in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Sipuleucel-T with Booster|BIOLOGICAL: Sipuleucel-T without Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High PEEP Application Following Pulmonary Thromboendarterectomy; Does it Have Any Impact on Outcome?
Status: COMPLETED
Conditions: Reperfusion Injury After Pulmonary Thromboendarterektomy
Interventions: OTHER: PEEP|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Behavioural Skill Training for Young Children With Severe Autism
Status: UNKNOWN
Conditions: Autistic Disorder
Interventions: BEHAVIORAL: Functional Behavioural Skills Group and Parent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Single Subcutaneous Dose (Part A) of PB1023 or Placebo (0.9% NaCl)|DRUG: Multiple (Four Weekly) Subcutaneous Injections (Part B) of PB1023 or Placebo (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shear Stress in the Arteries of the Lower Limbs During Exercise in Patients With Peripheral Arterial Disease
Status: ENROLLING_BY_INVITATION
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Arm-cranking exercise|OTHER: Heating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Does Optical Coherence Tomography Optimize Revascularization (DOCTOR) Recross Study
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: DEVICE: Xience Prime Stent|DEVICE: Medtronic Resolute Integrity stent|PROCEDURE: Angiography|PROCEDURE: OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury|Critical Illness Myopathy|Dialysis; Complications
Interventions: DIAGNOSTIC_TEST: Musculoskeletal ultrasound|DIAGNOSTIC_TEST: Assessments of muscle strength and physical function|DIAGNOSTIC_TEST: Metabolomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stress Reduction in Formerly Preeclamptic Women; Sofa or Sports
Status: ENROLLING_BY_INVITATION
Conditions: Preeclampsia|Stress, Psychological|Stress, Physiological|Sports Physical Therapy
Interventions: BEHAVIORAL: Aerobic exercise training|BEHAVIORAL: Mindfulness Based Stress Reduction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Radiation and PD-1 Inhibition in Metastatic or Recurrent Renal Cell Carcinoma (RCC)
Status: WITHDRAWN
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Nivolumab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine Plus Oxaliplatin Plus Bevacizumab as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin/metformin XR|DRUG: Placebo|DRUG: Metformin|DRUG: Thyroid hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate|DRUG: Quinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Herceptin (Trastuzumab) in Combination With Avastin (Bevacizumab) and Sequential Xeloda (Capecitabine) or Docetaxel in Patients With HER2-Positive Locally Recurrent or Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]|DRUG: docetaxel|DRUG: trastuzumab [Herceptin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety,Efficacy of Anti-EGFR Humanized Monoclonal Antibody Combined With Chemotherapy in Advanced Solid Tumors.
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: HLX07+Gemcitabine+Cisplatin|DRUG: HLX07+Paclitaxel+Carboplatin|DRUG: HLX07+mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: QoL and Cognitive Function in Patients With Hypoparathyroidism
Status: COMPLETED
Conditions: Hypoparathyroidism|Pseudo Hypoparathyroidism
Interventions: DIAGNOSTIC_TEST: MRI scans|DIAGNOSTIC_TEST: Neuro cognitive tests|DIAGNOSTIC_TEST: Questionnaires on Quality of Life|DIAGNOSTIC_TEST: Blood samples|DIAGNOSTIC_TEST: 24 hr urine samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib.
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3209590 in Japanese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3209590|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetic Resonance Technique in the Assessment of Exercise-induced Long- and Short-Term Changes in Cardiac Function and Morphology
Status: COMPLETED
Conditions: Myocardial Ischemia|Myocardial Infarction|Ventricular Remodeling|Myocardial Contraction|Ventricular Hypertrophy
Interventions: OTHER: repeated long term endurance exercise|OTHER: Other
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of a Standard Paracetamol Tablet and Oral Solution After Oral Administration in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Focus of Study: Pharmacokinetics Analysis, in Vivo Dissolution Studies
Interventions: DRUG: paracetamol oral solution|DRUG: paracetamol tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Low Back Pain Knowledge-Related Education on Attitudes and Knowledge in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Longitudinal Investigation of Skin Barrier Development From Birth and the Validation of Early Predictors of Atopic Eczema Risk: the Skin Testing for Atopic Eczema Risk (STAR) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Eczema
Interventions: DIAGNOSTIC_TEST: Skin Testing for Atopic eczema
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy
Status: RECRUITING
Conditions: Macular Polypoidal Choroidal Vasculopathy (PCV)
Interventions: DRUG: Brolucizumab 6mg|DRUG: Brolucizumab 6mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Status: NOT_YET_RECRUITING
Conditions: Sarcoma
Interventions: DRUG: Administration of L-TC|RADIATION: HFRT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Online Training Program for Physiotherapists About Weight Management for People With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Overweight and Obesity
Interventions: OTHER: Online training program in weight management for osteoarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Mechanism of TCCRP in Patients With Chronic Coronary Syndrome Under Fusion Cardiac Rehabilitation Model
Status: UNKNOWN
Conditions: Coronary Heart Disease|Chronic Coronary Syndrome
Interventions: BEHAVIORAL: Control Group ：conventional exercise rehabilitation programs (CERP)|BEHAVIORAL: Experimental Group ：Tai Chi cardiac rehabilitation program (TCCRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Celecoxib on Perioperative Inflammatory Response in Colon Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Colon Cancer
Interventions: DRUG: Celecoxib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TKI and Interferon Alpha Evaluation Initiated by the German Chronic Myeloid Leukemia Study Group - the TIGER Study
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Peginterferon α2b|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems
Status: COMPLETED
Conditions: Pulpitis
Interventions: PROCEDURE: Reciproc|PROCEDURE: One Shape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Late In-the-bag intraOcular Lens dislocatioN Surgery
Status: UNKNOWN
Conditions: Intraocular Lens Dislocation
Interventions: PROCEDURE: IOL repositioning|PROCEDURE: IOL exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine in Combination With Lenalidomide and Dexamethasone in Refractory or Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Bendamustine|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Aspirin|DRUG: Prophylaxis|DRUG: Antibiotic|OTHER: Biweekly Follow Up|OTHER: Cyclical Follow Up|OTHER: Restaging|OTHER: Post-Treatment Follow Up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Refractory Hypertension (Carvedilol)
Status: WITHDRAWN
Conditions: Hypertensive
Interventions: DRUG: Carvedilol|DRUG: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity in People With Borderline Personality Disorder (PABORD)
Status: NOT_YET_RECRUITING
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Structured Physical Activity Programme|BEHAVIORAL: Psychoeducational Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor, Carfilzomib, and Dexamethasone Versus Placebo, Carfilzomib, and Dexamethasone in Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Placebo (for selinexor)|DRUG: carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous/Nonmalignant Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 131I-rituximab for Relapsed or Refractory Marginal Zone B-cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed or Refractory Marginal Zone B-cell Lymphoma
Interventions: DRUG: 131I-rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 and Pemetrexed Disodium in Treating Patients With Relapsed Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: cediranib maleate|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial Evaluating the Efficacy of Nedaplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: nedaplatin and docetaxel|DRUG: cisplatin and docetaxel|DRUG: nedaplatin and docetaxel|DRUG: cisplatin and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Heart to Guide Myocardial Injury Patients to Wean From Ventilation
Status: RECRUITING
Conditions: Myocardial Ischaemia During Surgery
Interventions: DIAGNOSTIC_TEST: cardiac output index monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chromoscopic Guided Endomicroscpy to Diagnose Colitis Associated Dysplasia
Status: COMPLETED
Conditions: Ulcerative Colitis|Intraepithelial Neoplasia|Cancer
Interventions: DEVICE: Endomicroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Improve the Magnetic Levator Prosthesis
Status: COMPLETED
Conditions: Blepharoptosis|Ptosis, Eyelid|Myasthenia Gravis|Stroke|Traumatic Brain Injury
Interventions: DEVICE: Magnetic Levator Prosthesis (MLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fenretinide|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Surgery
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Surgery
Interventions: DRUG: Flecainide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess the Efficacy and Safety of Preoperative Chemo With Radiation Therapy for Patients With Borderline Unresectable Adenocarcinoma of the Pancreas
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|RADIATION: Radiation therapy|PROCEDURE: pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cytokine-induced Killer Cells for Stage I-II Malignant Gliomas
Status: NOT_YET_RECRUITING
Conditions: Cytokine-Induced Killer Cells|Milignant Gliomas
Interventions: DRUG: Temozolomide|BIOLOGICAL: CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Food Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ondansetron Orally Disintegrating Tablets 8 mg|DRUG: Zofran ODT® Tablets 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulations
Status: RECRUITING
Conditions: Liver Transplantation|Immunosuppression|Neurotoxicity|Tremor|Tacrolimus
Interventions: DRUG: Tacrolimus, Immediate Release, Oral|DRUG: Tacrolimus Extended Release Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib (Iressa) in Combo With Chemoradiation in Patients With Locally Advanced Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Gefitinib|DRUG: Cisplatin|PROCEDURE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Performance and Safety of CBL-102 Versus Vismed® Multi Eye Drops in the Management of Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: CBL-102 eye drops|DEVICE: Vismed Multi eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabetic Neuropathy
Interventions: PROCEDURE: Placebo|PROCEDURE: Pulsatile IV insulin delivery (humalog, humulin, novolog)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Blood Flow Variation in Continuous Renal Replacement Therapy
Status: TERMINATED
Conditions: Acute Kidney Injury|End-stage Renal Disease
Interventions: DEVICE: continuous renal replacement therapy using System One (TM) setup (Nxstage)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin A and Very Low Birthweight Babies (VitAL)
Status: COMPLETED
Conditions: Preterm Birth|Retinopathy of Prematurity
Interventions: DRUG: Aquasol A|DRUG: aquasol A|OTHER: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: low dose hMSC-Exos|BIOLOGICAL: medium dose hMSC-Exos|BIOLOGICAL: high dose hMSC-Exos|BIOLOGICAL: Dosage 1of hMSC-Exos|BIOLOGICAL: Dosage 2 of hMSC-Exos|BIOLOGICAL: No hMSC-derived exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Locally Advanced or Metastatic, Unresectable Soft Tissue Sarcoma|Sarcoma|Soft Tissue Sarcoma
Interventions: DRUG: AMG 655|OTHER: Placebo|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Time-effect of FEST+TST in the Upper-extremity Rehabilitation of Individuals With Traumatic SCI
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: FES Therapy combined with task-specific training (FEST+TST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Fixed Dose Combination (FDC) Dutasteride and Tamsulosin Hydrochloride (HCl) Relative to One Dutasteride and One Tamsulosin HCl Tablet in Healthy Male Subjects
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: FDC capsule of dutasteride and tamsulosin|DRUG: Dutasteride soft gelatine capsule and tamsulosin HCl oral disintegrating tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lidocaine Gel in Reducing Foley Catheter Discomfort in Surgical Patients
Status: UNKNOWN
Conditions: Urinary Catheter Discomfort in Surgical Patients
Interventions: DRUG: Lidocaine gel|DRUG: standard gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Letrozole Versus Clomifene Citrate for Ovulation Induction
Status: COMPLETED
Conditions: Infertility|Polycystic Ovarian Syndrome
Interventions: DRUG: Letrozole|DRUG: Clomifene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)
Status: RECRUITING
Conditions: CKD Stage 3|CKD Stage 4|CKD Stage 5
Interventions: DEVICE: EndoAVF System for endovascular AV fistula creation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intratumoral Gemcitabine, Paclitaxel, Carboplatine and Intravenous Nivolumab for Locally Recurrence of Head and Neck Cancers
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck|Paclitaxel|Carboplatin|Nivolumab
Interventions: DRUG: GCP intratumoral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clindamycin 300 mg Capsules in Healthy Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clindamycin 300 mg capsule|DRUG: Cleocin HCl 300 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluate the Efficacy of Armodafinil for Patients With B-cell Lymphoma and Severe Fatigue
Status: WITHDRAWN
Conditions: B-cell Lymphoma|Fatigue
Interventions: DRUG: Armodafinil|DRUG: placebo|DRUG: Armodafinil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Ointment on Temporomandibular Joint and Masticatory Muscle Pain
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: DRUG: Ping On Ointment|DRUG: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Education Via Phone-based Text Messaging (SMS) on Patients With Uncontrolled Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Education via SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Azacitidine and Pembrolizumab in Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreas Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of 28-day Inhaled CHF 6001 DPI in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: CHF6001 DPI|DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-relationship of Vaginally Administrated Oxytocin in Postmenopausal Women
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Oxytocin 100 i.u.|DRUG: Oxytocin 400 i.u.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brilliant Blue Versus Indocyanine Green
Status: UNKNOWN
Conditions: Macular Pucker|Macular Hole|Vitreoretinal Surgery
Interventions: PROCEDURE: Indocyanine green|PROCEDURE: Brilliant blue arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-year Follow-up Study of Subjects Who Participated in a Previous Asunaprevir (BMS-650032) and/or Daclatasvir (BMS-790052) Chronic Hepatitis C Clinical Trial
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Asunaprevir (BMS-650032) and/or Daclatasvir (BMS-790052)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Capacity of Patients With Chronic Obstructive Pulmonary Disease With and Without Supplementation of Whey
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Dietary Supplements|Rehabilitation
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optical Coherence Tomography in Tissue Samples From Women Undergoing Mastectomy for the Treatment or Prevention of Breast Ductal Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Precancerous Condition
Interventions: PROCEDURE: histopathologic examination|PROCEDURE: optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Adipose-Derived Stromal Cells Delivered Intra-articularly in Patients With Osteoarthritis.
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Liposuction with Local Anesthesia|BIOLOGICAL: Intra articular infusion of AD-SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boost Intentions and Facilitate Action to Promote COVID-19 Booster Take-up
Status: RECRUITING
Conditions: COVID-19|Vaccines
Interventions: BEHAVIORAL: Eligibility reminder|BEHAVIORAL: Link to a narrow set of vaccine venues|BEHAVIORAL: Link to a broad set of vaccine venues|BEHAVIORAL: Doctors' recommendation and value of vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biomechanical Osteoarthritis Outcomes in Meniscectomy Patients
Status: COMPLETED
Conditions: Meniscus Injury|Meniscectomy|Osteoarthritis, Knee
Interventions: PROCEDURE: Meniscectomy|OTHER: Helathy control comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Tele-visit on Patients Continous Positive Airway Pressure (CPAP) Follow-up by Home Care Provider
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: tele-visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-mold Azole in the Prophylaxis for Invasive Fusariosis
Status: COMPLETED
Conditions: Fusariosis|Onychomycosis
Interventions: DRUG: Voriconazole or posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study To Assess GW433908 (Fosamprenavir) Containing Regimens In HIV-1 Infected Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: fosamprenavir (GW433908)|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Toripalimab Injection Combined With Standard Chemotherapy as a First-line Treatment for Locally Advanced or Metastatic Urothelial Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced or Metastatic Urothelial Carcinoma
Interventions: BIOLOGICAL: Toripalimab Injection|DRUG: Gemcitabine Hydrochloride for Injection|DRUG: Cisplatin for Injection / Carboplatin Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia
Status: COMPLETED
Conditions: Anemia|Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Drug Toxicity|Radiation Toxicity|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage IVA Cervical Cancer
Interventions: RADIATION: External Beam Radiation Therapy|DRUG: Cisplatin|RADIATION: Internal Radiation Therapy|BIOLOGICAL: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-Reflux Mucosal Ablation(ARMA) and Anti-Reflux Mucosectomy(ARMS) in Gastroesophageal Reflux Disease
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux Disease|Endoscopy
Interventions: PROCEDURE: Anti-Reflux Mucosectomy|PROCEDURE: Anti-reflux mucosal ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT