pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Care4Today v2.0 Application for Improving Adherence to HIV Medications
Status: COMPLETED
Conditions: HIV|AIDS
Interventions: BEHAVIORAL: Care4Today v2.0 mobile application + electronic monitoring of adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: OTHER: Best Practice|OTHER: Communication Intervention|OTHER: Electronic Health Record Review|OTHER: Survey Administration|OTHER: Video Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VR-based Avatar Therapy for Treatment of Auditory Hallucinations
Status: RECRUITING
Conditions: Hallucinations, Auditory|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: BEHAVIORAL: AVATAR therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality for Pain-related Movement Dysfunctions in Patients With Chronic Shoulder Pain
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain|Virtual Reality|Movement Disorders
Interventions: DEVICE: Oculus Quest 2|DEVICE: Oculus Quest 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Experiencing a PMR Relapse
Status: RECRUITING
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Release Local Anesthetic for Postsurgical Pain After Posterior Colporrhaphy and Perineorrhaphy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Liposomal bupivacaine|DRUG: Placebo - injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asthma Express: Bridging the Emergency to Primary Care in Underserved Children
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Asthma Express Intervention|BEHAVIORAL: Standard Asthma Education Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of D-cycloserine on Emotional Processing
Status: COMPLETED
Conditions: Cycloserine|Healthy Volunteer
Interventions: DRUG: d-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment
Status: COMPLETED
Conditions: Chronic Hepatitis c|Cirrhosis, Liver|Fibrosis, Liver|Hepatic Cirrhosis
Interventions: DRUG: Peginterferon alfa-2a + Ribavirin|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery
Status: COMPLETED
Conditions: Post Partum Hemorrhage|Fibrinolysis; Hemorrhage|Blood Loss
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Interferon-Lovastatin Therapy for Malignant Melanoma
Status: WITHDRAWN
Conditions: Melanoma|Malignant Melanoma
Interventions: DRUG: lovastatin|DRUG: interferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Adult Male and Female Volunteers
Interventions: DRUG: AVP-923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy
Status: UNKNOWN
Conditions: Dry Eye Disease|Cataract Surgery|Ocular Surface Disease
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Myl1401O + Taxane vs Herceptin©+ Taxane for 1st Line, Met. Br. Ca.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Trastuzumab|BIOLOGICAL: MYL- 1401O|DRUG: Paclitaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Microbiota and Iron Status After Iron Fortification of Complementary Foods
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DIETARY_SUPPLEMENT: fortification with iron and micronutrients|DIETARY_SUPPLEMENT: Sprinkles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low and Intermediate Risk oliGometastatic coloREctal cancEr patieNts Treated With Stereotactic ABlative Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: RADIATION: SABR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Estimate The Effects Of Itraconazole On Pharmacokinetics Of Pf-06649751 In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF06649751, Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: oregovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: How Does Manual Therapy Improve Low Back Pain for Soldiers?
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Soft Tissue|PROCEDURE: Myofascial release|PROCEDURE: Counterstrain|PROCEDURE: Muscle energy|PROCEDURE: Sacro-iliac articulation|PROCEDURE: High-velocity, low amplitude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases
Status: COMPLETED
Conditions: Brain Metastasis|Bladder Cancer|Breast Cancer|Cervical Cancer|Colon Cancer|HEENT Cancer|Lung Cancer|Melanoma|Pancreatic Cancer|Prostate Cancer|Rectal Cancer|Sarcoma|Testicular Cancer
Interventions: RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Effect of HC-SVT-1001 and HC-SVT-1002 in the Surgical Treatment of Atrophic Pseudarthrosis of Long Bones (Bonecure)
Status: COMPLETED
Conditions: Pseudoarthrosis
Interventions: OTHER: HC-SVT-1001(initial protocol); HC-SVT-1002 (protocol amendment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Gynecologic Neoplasm|Healthy Women
Interventions: DRUG: Dimenhydrinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of BCD-148 and Soliris® for the Treatment of Patients With Paroxysmal Nocturnal Hemoglobinuria
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: BIOLOGICAL: BCD-148|BIOLOGICAL: Soliris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu
Status: TERMINATED
Conditions: Pneumonia, Viral|Influenza in Humans
Interventions: DRUG: hydrocortisone|DRUG: isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patching for Lazy Eye: Trial to Evaluate Daily Patching Amounts
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: 6 hours occlusion by patching|DEVICE: 12 hours occlusion by patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Evaluate the Application of NLAC Cream in Adults With Atopic Dermatitis
Status: UNKNOWN
Conditions: Staphylococcus Aureus|Atopic Dermatitis
Interventions: DEVICE: Natural Lactic Acid-enriched Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U.S. Study of Fibrocaps in Surgical Hemostasis
Status: COMPLETED
Conditions: Postoperative Hemorrhage
Interventions: DEVICE: Fibrocaps (fibrin sealant)|DEVICE: Gelfoam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Osseodensification Versus Osseodensification With Ridge Splitting in Horizontally Deficient Ridge
Status: NOT_YET_RECRUITING
Conditions: Osseodensification
Interventions: PROCEDURE: Ridge splitting followed by ossedensificaion|PROCEDURE: Osseodensification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of XC243 in Patients With Exacerbation of Chronic Cystitis
Status: NOT_YET_RECRUITING
Conditions: Cystitis
Interventions: DRUG: XC243 25 mg|DRUG: XC243 50 mg|DRUG: XC243 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery
Status: WITHDRAWN
Conditions: Bowel Disease|Liver Diseases|Pancreas Disease|Anesthesia; Functional
Interventions: DRUG: Ropivacaine-Sufentanil|DRUG: Dextrose 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
Status: COMPLETED
Conditions: Acute Bacterial Skin and Skin Structure Infections
Interventions: DRUG: Oral Levonadifloxacin/Linezolid Tablet|DRUG: Intravenous Levonadifloxacin/Linezolid Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Different Doses of Pregabalin as a Multimodal Analgesic Agent in Postoperative Pain Control After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Pregabalin 75mg|DRUG: Pregabalin 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Baseline Computed Tomography (CT) Perfusion Parameters of Pancreatic Cancer for Patients Undergoing Stereotactic Body Radiotherapy or Surgical Resection
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Stereotactic body radiotherapy|DRUG: Iodixanol|DRUG: Iohexol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
Status: RECRUITING
Conditions: Cancer|Malignancy|Malignant Neoplasm
Interventions: OTHER: Digital Intervention|OTHER: Community Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: DRUG: TDF/FTC 300mg/200mg fixed-dose combination tablets|DRUG: TAF/FTC 25mg/200mg fixed-dose combination tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Tolerability of Libella Gene Therapy for Critical Limb Ischemia: AAV- hTERT
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: DRUG: AAV-hTERT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Mood Disorders by Folic Acid Supplementation
Status: COMPLETED
Conditions: Depression|Bipolar Disorder
Interventions: DRUG: Folic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effects of Probiotic Toothpastes on Periodontal Health
Status: ENROLLING_BY_INVITATION
Conditions: Periodontal Diseases|Periodontitis|Gingivitis
Interventions: OTHER: Using Probiotic Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Icotinib Combined With Dihydroaremisinin (DHA) Therapy in Patients With Advanced NSCLC
Status: UNKNOWN
Conditions: EGFR Positive Non-Small Cell Lung Cancer,Adenocarcinoma
Interventions: DRUG: Icotinib combined dihydroaremisinin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Vorinostat in Treating Patients With Recurrent Mantle Cell Lymphoma or Recurrent and/or Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma
Interventions: DRUG: Bortezomib|OTHER: Laboratory Biomarker Analysis|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Traumatic Stress Disorder|Depression|Psychosocial Problem
Interventions: BEHAVIORAL: Cross-sectoral psychosocial intervention|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IntraCERvical Balloon Catheter in the Setting of Induction of Labor for Fetal Loss or Abortion
Status: NOT_YET_RECRUITING
Conditions: Abortion, Complete|Fetal Death|Induction of Labor Affected Fetus / Newborn
Interventions: DEVICE: Cook Cervical Ripening Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy|Partial-onset Seizures
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipoproteinemia(a)
Interventions: DRUG: Pelacarsen (TQJ230) 80 mg s.c.|DRUG: Corresponding Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RGX-104 in Patients With Advanced Lung & Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer|Endometrial Cancer Recurrent|Lung Cancer Recurrent|Lung Cancer|Non-small Cell Lung Cancer Metastatic|Non-small Cell Carcinoma
Interventions: DRUG: RGX-104|DRUG: Ipilimumab|DRUG: Docetaxel|DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617|OTHER: Best supportive/best standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CRT-D and CRT-DX Systems (CRT-NEXT)
Status: RECRUITING
Conditions: Heart Failure|Cardiac Resynchronization Therapy
Interventions: DEVICE: Conventional 3-lead CRT defibrillator system implantation|DEVICE: 2-lead CRT defibrillator system implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valproate Versus Ketorolac Versus Metoclopramide
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: Metoclopramide|DRUG: Ketorolac|DRUG: Valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ellagic Acid From Pomegranate Juice vs. Pure Ellagic Acid on Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Pomegranate Juice|DIETARY_SUPPLEMENT: Ellagic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I/II Study of OBI-3424 in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Pancreatic Adenocarcinoma
Interventions: DRUG: OBI-3424
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Aerobic Exercise on Cognitive Functioning in Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Aerobic Exercise|OTHER: Standard Psychiatric Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Pharmacokinetics of Venlafaxine Extended-Release (ER) and Desvenlafaxine Succinate Sustained-Release (DVS SR) 50 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release (DVS SR)|DRUG: Venlafaxine Extended Release (VEN ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Avelumab and M1774 in ARID1A-mutated Endometrial Cancer (Prior IO)
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer|ARID1A Gene Mutation|Recurrent Endometrial Carcinoma
Interventions: DRUG: Avelumab|DRUG: M1774
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Status: COMPLETED
Conditions: Brain Tumor|Astrocytoma|Astroglioma|Glioblastoma|Gliosarcoma
Interventions: DRUG: Zotiraciclib (TG02)|DRUG: Temozolomide (TMZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma
Status: RECRUITING
Conditions: Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Adult T-Cell Leukemia/Lymphoma|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Mogamulizumab|BIOLOGICAL: Natural Killer Cell Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clear Aligners for the Treatment of Dental Malocclusion in OI
Status: RECRUITING
Conditions: Osteogenesis Imperfecta
Interventions: DEVICE: Invisalign
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PARP Inhibition for Gliomas (PI-4G or π4g)
Status: TERMINATED
Conditions: Recurrent Glioblastoma|Recurrent Astrocytoma|Recurrent Oligodendroglioma|Recurrent Glioma
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Utilization of Nintendo Wii™ in Outpatient Rehabilitation Following Total Knee Replacement
Status: COMPLETED
Conditions: Arthropathy of Knee Joint
Interventions: OTHER: Wii Fit|OTHER: Lower Extremity Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Treatment With Colistin on Mortality Bacteremia Multiresistant Acinetobacter Baumannii Sensitive Colistin in Patients Critical
Status: COMPLETED
Conditions: Acinetobacter Infections
Interventions: DRUG: Colistin|DRUG: Tigecycline|DRUG: Vancomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D Metabolism in Patients With Endocrine Disorders
Status: COMPLETED
Conditions: Pituitary ACTH Hypersecretion|Acromegaly|Diabetes Mellitus, Type 1|Primary Hyperparathyroidism
Interventions: DRUG: Cholecalciferol 15000 UNT/ML Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sargramostim or Hypertonic Saline Before Sentinel Lymph Node Biopsy in Treating Patients With Stage IB-II Melanoma
Status: WITHDRAWN
Conditions: Stage IB Melanoma|Stage IIA Melanoma|Stage IIB Melanoma|Stage IIC Melanoma
Interventions: BIOLOGICAL: sargramostim|PROCEDURE: sentinel lymph node biopsy|OTHER: laboratory biomarker analysis|OTHER: hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAndesartan vs LIsinopril Effects on the BRain
Status: COMPLETED
Conditions: Hypertension|Mild Cognitive Impairment
Interventions: DRUG: Candesartan|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rapid Declarative Neocortical Declarative Learning in Aging and Memory Diseases (ANéRAVIMM)
Status: RECRUITING
Conditions: Neurological Diseases|Central Nervous System
Interventions: OTHER: Neuropsychological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma|Acute Lymphoblastic Leukemia|Diffuse Large B Cell Lymphoma|Triple Negative Breast Cancer Malignancies
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: PRGN-3007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-harm Behaviour Among the Most At-risk Adolescents
Status: RECRUITING
Conditions: Self-harm|Personality Disorder, Borderline|Epigenetic Disorder|Non-Suicidal Self Injury|Change; Mental|Difference, Individual
Interventions: DIAGNOSTIC_TEST: Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3|DIAGNOSTIC_TEST: Columbia Suicide Severity Rating Scale (CSSRS)|DIAGNOSTIC_TEST: The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)|DIAGNOSTIC_TEST: Experiences in Close Relationships-Relationship Structures (ECR-RS)|DIAGNOSTIC_TEST: Trauma Symptom Checklist for Children (TSCC)|DIAGNOSTIC_TEST: Personality Assessment Inventory-Adolescent (PAI-A)|DIAGNOSTIC_TEST: Inventory Of Statements About Self-Injury; ISAS|DIAGNOSTIC_TEST: The Level of Personality Functioning Scale-Brief Form 2.0; LPFSBF 2.0|DIAGNOSTIC_TEST: Borderline Personality Features Scale, BPFSC-11|OTHER: Dynamic Appraisal of Situational Aggression-Youth Version (DASA-YV)|OTHER: Adolescent Self-Harm Risk Scale; ASHRS|DIAGNOSTIC_TEST: Lifetime Incidence of Traumatic Events questionnaire (LITE)|GENETIC: Genetic methods
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: BIOLOGICAL: NBS10|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomas
Status: COMPLETED
Conditions: Ewing's Sarcoma|Rhabdomyosarcoma
Interventions: DRUG: EF-1 Peptide|DRUG: EF-2 Peptide|DRUG: PXFK Peptide|DRUG: E7 Peptide|DRUG: IL-2|DRUG: IL-4|DRUG: GM-CSF|DRUG: CD40 Ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: RIC-NEC Randomized Controlled Trial
Status: RECRUITING
Conditions: Necrotizing Enterocolitis
Interventions: OTHER: Remote ischemic conditioning (RIC) + Standard of Care for NEC|OTHER: Standard of Care for NEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Presence of Signs of Central Sensitization in Episodic and Chronic Migraine
Status: COMPLETED
Conditions: Central Sensitisation|Migraine
Interventions: OTHER: Pressure pain thresholds|OTHER: Thermal detection and pain thresholds|OTHER: Temporal summation|OTHER: Conditioned pain modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Sleep Deprivation and Adrenergic Inhibition on Glymphatic Flow in Humans
Status: COMPLETED
Conditions: Sleep Deprivation|Sleep Wake Disorders|Sleep
Interventions: DRUG: Carvedilol 25mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Ready-to-use" Intra-articular Formulation of Mesenchymal Stromal Cells
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: BIOLOGICAL: "Ready to inject" Umbilical cord-derived Mesenchymal Stromal Cell (MSC) product|BIOLOGICAL: Resuspended Umbilical cord-derived Mesenchymal Stromal Cell (MSC) product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Octreotide Acetate and Cabergoline in Patients With Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Octreotide acetate and cabergoline/Octrotide and Somavert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Vecuronium and Cisatracurium on Electrophysiologic Monitoring During Neurosurgery
Status: COMPLETED
Conditions: Motor Evoked Potential Monitoring|General Anesthesia|Neurosurgery|Brain Tumor|Spine Tumor|Cerebral Aneurysm
Interventions: OTHER: MEP monitoring with continuous infusion of vecuronium during general anesthesia|OTHER: MEP monitoring with continuous infusion of cisatracurium during general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Spirulina Supplementation and Cardiovascular Risk in Obese Caucasians With Treated Hypertension
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Spirulina|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetic/Pharmacodynamic Interactions and Safety Between ID1801 and ID1803 in Healthy Male Adults
Status: UNKNOWN
Conditions: Hypertension|Dyslipidemias
Interventions: COMBINATION_PRODUCT: ID1803|COMBINATION_PRODUCT: ID1801|COMBINATION_PRODUCT: ID1803+ID1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locally Ablative TherapY in Oligo-ProgressiVe GEnitourinary TumoRs (LAYOVER)
Status: RECRUITING
Conditions: Prostate Cancer|Oligoprogressive|Urothelial Carcinoma|Renal Cell Carcinoma
Interventions: DEVICE: Ablative local therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExBonAdAsia Study: A Study of Once Monthly Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis.
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERFECT Project - Part 1 - Study 3
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: Control|OTHER: Pea flour|OTHER: Pea fibre|OTHER: Pea protein|OTHER: Pea flour + pea protein|OTHER: Pea fibre + pea protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ED Management of Severe Hyperglycemia: A Clinical Trial
Status: COMPLETED
Conditions: Hyperglycemia|Diabetes Mellitus|Complications of Diabetes Mellitus|Diabetes-Related Complications|Diabetes Mellitus, Type 2
Interventions: OTHER: Tight control: goal glucose 350 mg/dL or lower|OTHER: Loose control: goal glucose 600 mg/dL or lower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-In-Range Based Risk Stratification of Type 2 Diabetes Microvascular Complications
Status: RECRUITING
Conditions: Type 2 Diabetes|Diabetes Related Complications|Diabetes; Retinopathy (Manifestation)|Diabetes; Neuropathy, Polyneuropathy (Manifestation)|Diabetes; Nephropathy (Manifestation)
Interventions: DIAGNOSTIC_TEST: Diabetes Microvascular Complication Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: dihydroartemisinin-piperaquine (DHAp)|PROCEDURE: reactive case detection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcriptomics of Mononuclear Cells and Inflammatory Status of Obese Patients Treated With Omega-3 Fatty Acids
Status: WITHDRAWN
Conditions: Obesity|Inflammation|Immune System Disorder
Interventions: DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Change in Foveal Avascular Zone After Removal of Epiretinal Membrane and Internal Limiting Membrane
Status: UNKNOWN
Conditions: Epiretinal Membrane
Interventions: PROCEDURE: epiretinal membrane and internal limiting membrane removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Deep Sea Krill Oil Supplementation in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Swisse High Strength Deep Sea Krill Oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Accelerated Learning in Healthy Subjects: Trigeminal Nerve Stimulation
Status: TERMINATED
Conditions: Healthy Adults
Interventions: DEVICE: Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Brief GAmeplay Intervention for NHS ICU Staff Affected by COVID-19 Trauma (GAINS Study)
Status: COMPLETED
Conditions: Intrusive Memories of Traumatic Event(s)
Interventions: BEHAVIORAL: Brief digital imagery-competing task intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a School-based WASH Intervention on Child Health and School Attendance in Addis Ababa, Ethiopia
Status: COMPLETED
Conditions: Diarrhea|Respiratory Tract Infections|Absenteeism
Interventions: OTHER: Splash WASH in Schools programme (Project WISE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia
Interventions: DRUG: Fitusiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Stomatitis, Aphthous
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Autogenous Bone Graft and Screw Tent-Pole Technique on Atrophic Mandible
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Autogenous block bone graft|PROCEDURE: i-PRF enriched allograft material+ screw tent pole technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Combined Nature-based and Virtual Mindfulness Intervention on Perceived Stress in Healthcare Workers
Status: ENROLLING_BY_INVITATION
Conditions: Stress, Psychological|Sleep Disturbance|Burnout, Caregiver|Posttraumatic Stress Disorder|Anxiety|Depression
Interventions: BEHAVIORAL: Nature Only|BEHAVIORAL: Nature+Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Therapy Response Monitoring in Melanoma Patients Using PET/MRI
Status: UNKNOWN
Conditions: Malignant Melanoma Stage IV
Interventions: DIAGNOSTIC_TEST: PET/MR (Biograph mMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Concurrent and Adjuvant Nimotuzumab Combined With Induction Chemotherapy Plus Chemoradiation in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma by AJCC V8 Stage
Interventions: DRUG: Nimotuzumab|DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Position and Renal Resistive Index
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Acute Kidney Injury|Prone Position|Intra-Abdominal Hypertension
Interventions: OTHER: Prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Cryolipolysis on Insulin Resistance
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus in Obese|Cryotherapy Effect
Interventions: PROCEDURE: Cryolipolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Enhanced implementation package|BEHAVIORAL: Standard implementation package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extracorporeal Membrane Oxygenation Evaluated by Transcranial Doppler.
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation Complication
Interventions: OTHER: Examination : a TCD and Trans-Thoracic Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Two Strengthening Protocols for Lower Limbs in Patients With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Posterolateral Hip Complex Exercises|OTHER: Anteromedial Hip Complex Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Human Acellular Dermal Matrix to Improve Infraauricular Depressed Deformities and Frey's Syndrome
Status: COMPLETED
Conditions: Parotid Tumor
Interventions: PROCEDURE: ADM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
Status: NOT_YET_RECRUITING
Conditions: Obstructed Labor
Interventions: DRUG: 8.4% sodium bicarbonate solution|OTHER: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pancreatic Enzymes in the Drains as Early Biomarkers of Post-operative Pancreatic Fistula and Its Clinical Repercussions
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: BIOLOGICAL: Lipase, amylase and CRP (C-reactive protein) dosages
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Efficacy of a Denture Adhesive to Seal Out Food Particles From Under the Mandibular Partial Denture
Status: COMPLETED
Conditions: Partial Denture
Interventions: DEVICE: Experimental Denture Adhesive|DEVICE: Fixodent True Feel Denture Adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
Status: RECRUITING
Conditions: Distal Radius Fractures|Lidocaine|Ropivacaine|Fracture Dislocation|Closed Reduction of Fracture and Application of Plaster Cast|Colles' Fracture
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution|DRUG: Lidocaine epinephrine|DRUG: Ropivacaine 0.5% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Biomarkers in Cell Samples From Young Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: fluorescence activated cell sorting|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Generic vs. Name-Brand Levothyroxine
Status: COMPLETED
Conditions: Congenital Hypothyroidism|Hypothyroidism
Interventions: DRUG: Brand Name Levothyroxine (Synthroid)|DRUG: Generic formulation of Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEpwise Research Program to Promote INGeniouS ONline Supportive Solutions in the Relief of Cancer-related Fatigue (STEPPING-STONe)
Status: NOT_YET_RECRUITING
Conditions: Cancer Diagnosis|Moderate or Severe Score of Cancer-related Fatigue (CRF)
Interventions: DEVICE: Educational content|DEVICE: Educational material plus self-management program - self-administered version|DEVICE: Educational material plus self-management program - guided version with mental health professional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Effect of Platelet Rich Plasma Combined With Laser on Scar
Status: COMPLETED
Conditions: Acne Scar
Interventions: PROCEDURE: fractional carbon dioxide laser with platelet rich plasma|PROCEDURE: fractional carbon dioxide laser with NS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Prevention Peer Navigation for Justice Involved Women
Status: UNKNOWN
Conditions: HIV Infections|Stigma, Social
Interventions: BEHAVIORAL: Standard of care engagement practices|BEHAVIORAL: Peer Navigators Addressing INtersectional Stigma to Improve HIV Prevention Among Criminal-Justice Involved Women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SP Robotic Versus VATS Anatomical Pulmonary Resection for Patients With NSCLC
Status: NOT_YET_RECRUITING
Conditions: Robotics|Lung Cancer
Interventions: PROCEDURE: Single-port robotic-assisted thoracic surgery|PROCEDURE: Single-port video-assisted thoracoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories
Status: COMPLETED
Conditions: Anemia
Interventions: COMBINATION_PRODUCT: Intervention factory with hot lunch|COMBINATION_PRODUCT: Intervention factory without lunch program|COMBINATION_PRODUCT: Control factory with lunch program|BEHAVIORAL: Control factory without lunch program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Study on Multiple Oral Dosing of CG100649
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CG100649|DRUG: Placebo|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial to Study Interventions to Increase Participation in Cervical Cancer Screening Program
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: OTHER: Telephone arm|OTHER: Self-test arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage|Intraventricular Hemorrhage
Interventions: DRUG: Tissue Plasminogen Activator|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT