pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Bio-Active-Stent to the Everolimus-Eluting Stent in Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Percutaneous coronary intervention|DEVICE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The DURATION Study: reDUcing sedentaRy behAviour to Maintain cogniTIve functiON.
Status: WITHDRAWN
Conditions: Sedentary Behavior|Mild Cognitive Impairment|Glucose Intolerance|Overweight and Obesity
Interventions: BEHAVIORAL: interrupting sedentary behaviour with light physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of New Treatment Strategy of Mucous Membrane Pemphigoid Using Large Dose of Prednisolone Plus Intra-lesional of Triamcinolone Acetonide Followed by Combination of Mycophenolate Mofetil, Dapsone and Low Dose Prednisolone
Status: UNKNOWN
Conditions: Benign Mucous Membrane Pemphigoid
Interventions: DRUG: large dose of prednisolone plus intra-lesional of Triamcinolone Acetonide followed the systemic combination of mycophenolate mofetil (MMF), dapsone and low dose prednisolone in treatment of MMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA
Status: COMPLETED
Conditions: Post Operative Pain|Total Knee Replacement
Interventions: DRUG: morphine and bupivacaine|DRUG: spinal morphine and marcaine|DRUG: morphine and bupivacaine|DRUG: morphine and bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ED Diabetes Screening and Outpatient Care
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Non Insulin Dependent Diabetes Mellitus
Interventions: OTHER: Telehealth Bridge Visits|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Preparative Regimen|BIOLOGICAL: Intravenous Recombinant Human IL-15 (rhIL-15)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Systemic Inflammatory Response in Critically Ill Children After Glutamine Supplementation
Status: COMPLETED
Conditions: Inflammatory Response|Multi-organ Failure
Interventions: DIETARY_SUPPLEMENT: solution of amino acids supplemented with glutamine|DIETARY_SUPPLEMENT: amino acids not supplemented with glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Immunotherapy Trial for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Glioma of Brain
Interventions: DRUG: IGF-1R/AS ODN|DEVICE: biodiffusion chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Clotiazepam 5 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Clotiazepam 5 mg Test Product Coated Tablets|DRUG: Clotiazepam 5 mg Reference Product Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients With Asthma (CPAP)
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Continuous Positive Airway Pressure device (Resmed, Swift, Mirage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters
Status: UNKNOWN
Conditions: Delirium|Pain|Sedation|Anxiety|Music|Intensive Care Unit Delirium
Interventions: OTHER: Music|OTHER: Earplug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebellar tDCS and Balance Training in PwMS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Balance Training|DEVICE: 2 mA Transcranial Direct Current Stimulation|DEVICE: 4 mA Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of a Diet and Exercise Intervention in Diabetics During Treatment for Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer|Diabetes Mellitus
Interventions: OTHER: CR diet|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance and Safety of Exufiber Ag+ and Exufiber on Partial Thickness Burns
Status: RECRUITING
Conditions: Partial-thickness Burn
Interventions: DEVICE: Exufiber|DEVICE: Exufiber Ag+
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction (DDI) Study for TPN171H
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: TPN171H|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Brain Metastases Treated With Stereotactic Radiotherapy Using Dynamic [18F]FDG PET
Status: NOT_YET_RECRUITING
Conditions: Brain Metastases
Interventions: DIAGNOSTIC_TEST: dynamic [18-FDG PET] scan post stereotactic radiation for brain metastases
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: New Therapies and Biomarkers for Chagas Infection
Status: COMPLETED
Conditions: Trypanosoma Cruzi Infection|Chagas Disease
Interventions: DRUG: Benznidazole|DRUG: Nifurtimox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Fluzone® Quadrivalent, Flublok® Quadrivalent, and Fluzone® High-Dose, Influenza Vaccines, 2018-2019 Formulations
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, 2018-2019 formulation|BIOLOGICAL: Flublok Quadrivalent vaccine, 2018-2019 formulation|BIOLOGICAL: Fluzone High-Dose vaccine, 2018-2019 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: Letetresgene autoleucel (lete-cel, GSK3377794)|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Beetroot Juice - Active|DRUG: beetroot juice - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2)
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Mechanical thrombectomy combined with ischemic post-conditioning|PROCEDURE: Mechanical thrombectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Addition of an Interdental Cleaning Device to Manual Brushing on Gingival Health
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Interdental cleaning device|DEVICE: Manual Tooth brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Status: COMPLETED
Conditions: Abdominal Surgery|Colon Surgery|Post-Op Infection
Interventions: DRUG: D_PLEX|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combined Corticosteroid With Low Volume Compared to High Volume in Impingement Syndrome
Status: COMPLETED
Conditions: Impingement Shoulder
Interventions: DRUG: Lidocaine 3 cc|DRUG: Lidocaine 9 cc|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Colorectal Cancer
Interventions: DRUG: SHR-A1811
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI)
Status: RECRUITING
Conditions: Chronic Limb-Threatening Ischemia|Peripheral Arterial Disease|Peripheral Vascular Disease
Interventions: BIOLOGICAL: BGC101 (autologous EnEPC preparation)|BIOLOGICAL: Control medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Acute|Leukemia|Leukemia Acute Promyelocytic Leukemia (APL)|Leukemia Acute Lymphoid Leukemia (ALL)|Leukemia Chronic Myelogenous Leukemia (CML)|Leukemia Acute Myeloid Leukemia (AML)|Leukemia Chronic Lymphocytic Leukemia (CLL)
Interventions: PROCEDURE: Allogeneic hematopoietic cell transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors|Lymphoma
Interventions: DRUG: ASTX660
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Weight Management Program for Weight Gain in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenic Disorders
Interventions: DRUG: Olanzapine Hydrochloride|PROCEDURE: Weight Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the PK, Safety, and Tolerability After Single and Multiple Dose Daridorexant in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Daridorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isobaric Spinal Ropivacaine Versus Hyperbaric Spinal Bupivacaine in Total Knee Arthroplasty in Geriatric Patients
Status: COMPLETED
Conditions: Total Knee Arthroplasty in Geriatric Patients|Spinal Anesthesia
Interventions: DRUG: Hyperbaric bupivacaine|DRUG: Isobaric ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Umbilical Cord Clamping in Term Cesarean Deliveries
Status: COMPLETED
Conditions: Cesarean Delivery|Delayed Separation of Umbilical Cord
Interventions: PROCEDURE: Delayed umbilical cord clamping|PROCEDURE: Early umbilical cord clamping|PROCEDURE: Milking of the umbilical cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of MLDL1278A After Subcutaneous and Intravenous Administration in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MLDL1278A|DRUG: MLDL1278A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: PreventiOn of DYSbioSis Complications With Autologous FMT in AML Patients
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Autologous Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Narrative Exposure Therapy|BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Standard Inpatient Care|OTHER: Waiting List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders
Status: COMPLETED
Conditions: AML|ALL|CLL|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|Multiple Myeloma|Aplastic Anemia|Myeloproliferative Disorder
Interventions: DRUG: Cyclophosphamide; Fludarabine; Cyclosporin; CAMPATH-1H (Alemtuzumab); GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Chronic Pain Syndrome|Inflammatory Response
Interventions: DRUG: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery Sealing Using the HARMONIC ACE+ Shears(HS) for VATS Lobectomy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DEVICE: HARMONIC ACE®+ Shears (HS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy
Status: RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: HRS-1893|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer
Status: SUSPENDED
Conditions: Lung Non-Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8
Interventions: PROCEDURE: Pulmonary Artery-First Surgical Technique|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Rapimelt|DRUG: [11C]AZ10419369
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of Triple Therapy With CJ-12420 in H. Pylori Positive Patients
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: CJ-12420/Clarithromycin/Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement
Status: TERMINATED
Conditions: Degenerative Arthritis|Rheumatoid Arthritis|Traumatic Arthritis
Interventions: DEVICE: Implantation of Integra Cadence Total Ankle Sysyem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence and Burden of Hepatitis D Virus Infection in China Through Preoperative Examination Test (Predict Study)
Status: NOT_YET_RECRUITING
Conditions: Hepatitis D|Hepatitis B|Antibodies; Anti-D|RNA Virus Infections
Interventions: DIAGNOSTIC_TEST: HDV-Ab (IgG), HDV-RNA, RNA genotype
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Liposomal Latanoprost in Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: Subconjunctival injection of liposomal latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of Budesonide and Albuterol Delivered by PT027 Compared With PT007 and PT008 Administered Separately.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A (Budesonide/Albuterol Sulfate metered dose inhaler)|DRUG: Treatment B (Budesonide metered dose inhaler)|DRUG: Treatment C (Albuterol Sulfate metered dose inhaler)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VELCADE® With Mitoxantrone and Etoposide for Leukemias
Status: COMPLETED
Conditions: Relapsed Acute Leukemia|Refractory Acute Leukemia
Interventions: DRUG: Bortezomib with mitoxantrone, etoposide and cytarabine|DRUG: Bortezomib 1.0mg/m^2|DRUG: Bortezomib 1.3mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib/Docetaxel Dose Escalation Trial
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compliance of Traditional Chinese Medicine in Young Patients With Rheumatic Diseases
Status: UNKNOWN
Conditions: Chronic Rheumatic Diseases
Interventions: OTHER: patient-tailored anti-arthritis herbs|OTHER: patient-tailored DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Respiratory Distress After Elective Caesarean Birth Through Knee-chest-flexion: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Transient Tachypnea of the Newborn
Interventions: PROCEDURE: Knee-to-chest-flexion manoeuvre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The GlasVEGAS Study (Glasgow Visceral & Ectopic Fat With Weight Gain in South AsianS)
Status: COMPLETED
Conditions: Diabetes|Weight Gain|Weight Loss|Cardiovascular Disease|Obesity
Interventions: BEHAVIORAL: Weight gain|BEHAVIORAL: Weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia B
Status: COMPLETED
Conditions: Severe Hemophilia B
Interventions: BIOLOGICAL: rFIXFc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Resection Technique for Medium-sized (10-20mm) Colorectal Polyps
Status: NOT_YET_RECRUITING
Conditions: 10-20mm Colorectal Polyp
Interventions: PROCEDURE: Endoscopic Mucosal Resection (EMR)|PROCEDURE: Cold Endoscopic Mucosal Resection (C-EMR)|PROCEDURE: Underwater Endoscopic Mucosal Resection (U-EMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Sub-study of the Neomindset Trial
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Dual antiplatelet therapy: Acetylsalicylic acid + ticagrelor OR Acetylsalicylic acid + prasugrel|DRUG: Monotherapy: Ticagrelor alone OR Prasugrel alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants
Status: RECRUITING
Conditions: Posaconazole|Pharmacokinetics|Invasive Candidiases|Invasive Aspergillosis|Invasive Mycosis|Fungal Infection|Prophylaxis
Interventions: DRUG: Posaconazole pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Medication After Coronary Artery Bypass Surgery (CABG) in Older Adults
Status: COMPLETED
Conditions: Coronary Artery Bypass Grafting (CABG) Surgery
Interventions: BEHAVIORAL: Motivational Interviewing (MI|BEHAVIORAL: volitional intervention|BEHAVIORAL: Routine discharge counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Status: COMPLETED
Conditions: Pulpitis
Interventions: DRUG: Articaine|DRUG: Articaine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of Sevacizumab in Combination With Chemotherapy in Chinese Patients With Platinum-Resistant Recurrent Ovarian Cancer.
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Sevacizumab|DRUG: Paclitaxel|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
Status: COMPLETED
Conditions: Inhalational Anesthetics Adverse Reaction|Delirium on Emergence|Strabismus Following Ocular Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste
Status: COMPLETED
Conditions: Pain|Symptomatic Irreversible Pulpitis
Interventions: DRUG: Nitrofurantoin|DRUG: Double Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Imaging and Endoplant-related Mechanical Complications After Long Segment Fixation and Fusion of Degenerative Lumbar Scoliosis (DLS)
Status: RECRUITING
Conditions: Degenerative Scoliosis
Interventions: PROCEDURE: Long Segment Fixation and Fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Exercise Therapy for Flexor and Extensor Cervical Muscles on Non-specific Neck Pain.
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Neck extensors training versus deep cervical flexors training, compared to a control group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Exploratory Efficacy Study of UCMSCs in Patients With Fracture and Bone Nonunion
Status: UNKNOWN
Conditions: Fracture|Bone Nonunion
Interventions: BIOLOGICAL: UCMSCs|BIOLOGICAL: Percutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: BBI608|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: Fluorouracil|DRUG: MM-398
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Secukinumab Versus Guselkumab in Clearing Psoriatic Plaques Refractory to Ustekinumab
Status: COMPLETED
Conditions: Chronic Plaque-type Psoriasis
Interventions: PROCEDURE: Skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hairy Cell Leukemia|Hairy Cell Leukemia Variant|Recurrent Hairy Cell Leukemia|Recurrent Hairy Cell Leukemia Variant
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Ibrutinib|PROCEDURE: Ultrasound Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline (Chantix™) for the Treatment of Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block and Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Abdominal Wall Muscles|Regional Anesthesia|Postoperative Pain
Interventions: PROCEDURE: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: aminolevulinic acid|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1b/2 Study of LDRT in Combination With AK104 Plus Chemotherapy as First-line Treatment for ES-SCLC
Status: RECRUITING
Conditions: SCLC, Extensive Stage
Interventions: DRUG: AK104|DRUG: Etoposide|DRUG: Carboplatin|RADIATION: low-dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid And Cholestasis Of Pregnancy
Status: WITHDRAWN
Conditions: Intrahepatic Cholestasis of Pregnancy
Interventions: DRUG: Ursodeoxycholic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC.
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Cisplatin + Gemcitabine with SUBATM-itraconazole|DRUG: Cisplatin + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalised Hyperlipidaemia Therapies Guided by Pharmacogenomics
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: Pharmacogenomics-directed Hyperlipidaemia Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls
Status: COMPLETED
Conditions: Rhinitis
Interventions: BIOLOGICAL: Capsaicin|BIOLOGICAL: diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Status: ACTIVE_NOT_RECRUITING
Conditions: Phantom Limb Pain
Interventions: BEHAVIORAL: Mirror Therapy on present Lower Limb|DIAGNOSTIC_TEST: Mental Imagery on present Lower Limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
Status: RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Educational Intervention|OTHER: Fecal Immunochemical Test|BEHAVIORAL: Patient Navigation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of LY2409021 on Blood Sugar Levels When Glucagon Levels Are Increased in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: LY2409021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia
Status: COMPLETED
Conditions: Unresectable Adenocarcinoma of the Esophagus|Metastatic Adenocarcinoma of the Esophagus|Unresectable Adenocarcinoma of Gastric Cardia|Metastatic Adenocarcinoma of Gastric Cardia
Interventions: DRUG: FOLFOX|DRUG: 5-FU|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sleep Intervention to Improve Outcomes Among Women at High Risk of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Sleep
Interventions: BEHAVIORAL: GO! To Sleep|BEHAVIORAL: Sleep information|PROCEDURE: Blood Draw|OTHER: Pittsburgh Sleep Quality Index (PSQI)|OTHER: Insomnia Severity Index (ISI)|OTHER: SF-12 quality of life survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TACE With Irinotecan Drug-eluting Beads and Intravenous (IV) Cetuximab in Refractory Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Irinotecan|DEVICE: Irinotecan eluting BEADS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Heart Rate Reduction on Central Arterial Pressure in Healthy Individuals
Status: TERMINATED
Conditions: Central Arterial Pressure
Interventions: DRUG: Ivabradine|DRUG: Metoprolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Motivational Interviewing to Acutely Admitted Psychiatric Patients With Comorbid Substance Use
Status: COMPLETED
Conditions: Substance-Related Disorders
Interventions: BEHAVIORAL: Motivational Interviewing|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Dementia
Interventions: DRUG: ladostigil hemitartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aluminium Foil as an Adjuvant to Phototherapy for Pathological Unconjugated Hyperbilirubinaemia in Full Term Infants
Status: COMPLETED
Conditions: Neonatal Jaundice
Interventions: DEVICE: Phototherapy with aluminum foil|DEVICE: Phototherapy without aluminum foil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Value of Hybrid PET/MR for Systemic Amyloidosis
Status: RECRUITING
Conditions: Systemic Amyloidosis|PET/MR
Interventions: DIAGNOSTIC_TEST: 11C-PIB or 18F-florbetapir PET/MR before biopsy and treatment|DIAGNOSTIC_TEST: 11C-PIB or 18F-florbetapir PET/MR after treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect and Tolerance of Standardized Exclusive Dry Extracts of Curcuma Longa and of Boswellia Serrata Among People With Hand Joint Discomfort and Dysfunction
Status: COMPLETED
Conditions: Hand Joint Discomfort|Hand Joint Dysfunction
Interventions: DIETARY_SUPPLEMENT: Flexofytol Forte|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Sarcoma|Neuroblastoma|Wilms Tumor|Osteosarcoma|Brain Tumor
Interventions: DRUG: Pazopanib (GW786034)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma
Status: TERMINATED
Conditions: Adult Lymphocyte Depletion Hodgkin Lymphoma|Adult Lymphocyte Predominant Hodgkin Lymphoma|Adult Mixed Cellularity Hodgkin Lymphoma|Adult Nodular Sclerosis Hodgkin Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Multiple Myeloma|Splenic Marginal Zone Lymphoma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma|Waldenström Macroglobulinemia
Interventions: DRUG: alvocidib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With Lu AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Lu AG09222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Administration of AdVEGF-All6A+ to Myocardium of Individuals With Diffuse CAD Via Minimally Invasive Surgery
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: BIOLOGICAL: AdVEGF-All6A+|BIOLOGICAL: AdNull
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.
Status: RECRUITING
Conditions: Laryngeal Squamous Cell Carcinoma|Hypopharynx Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Sentinel lymph node biopsy guided selective elective neck irradiation|RADIATION: Standard elective neck irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Cyanotic Heart Defects
Status: COMPLETED
Conditions: Postoperative Hemorrhage
Interventions: DRUG: Normal saline at induction|DRUG: Normal saline infusion|DRUG: Intravenous tranexamic acid|DRUG: infusion tranexamic acid|DRUG: topical tranexamic acid|DRUG: topical normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Effects of an Investigational Tampon on Vaginal Microflora
Status: COMPLETED
Conditions: Vaginal Microflora
Interventions: DEVICE: Experimental - Tampon with GML|DEVICE: Sham Control - Tampons without GML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Alfuzosin Treatment in Children and Adolescents With Hydronephrosis of Neuropathic Etiology
Status: COMPLETED
Conditions: Hydronephrosis|Neurogenic Bladder
Interventions: DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium-90 Radioembolization With Glass Microspheres (TheraSphere) for Patients With Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Selective internal radiation therapy of the liver with Yttrium-90 glass microspheres (TheraSphere)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exogenous Ketones on Exercise Performance in Young Healthy Adults
Status: COMPLETED
Conditions: Exercise|Ketones|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Ketone Salt|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Management of Neuropathic Pain With Ramelteon
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of the Treatment of Chronic Laryngitis With Amitryptiline
Status: TERMINATED
Conditions: Laryngeal Diseases|Chronic Laryngeal Neuropathy
Interventions: DRUG: Amitriptyline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
Status: RECRUITING
Conditions: Multiple Sclerosis|Fatigue
Interventions: BEHAVIORAL: 4-week Relaxation Training|BEHAVIORAL: 4-week Behavioral Activation|BEHAVIORAL: 4-week Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Aerosol Deposition With Vented and Unvented Jet Nebulizer in Healthy Subjets
Status: UNKNOWN
Conditions: Aerosol Drug Therapy
Interventions: DEVICE: Vented and Unvented Jet Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Low Dose Atazanavir/r Versus Standard Dose Atazanavir/r (LASA)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ATV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: GENETIC: IDgenetix Neuropsychiatric Test Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Micronutrient (Chromium) Supplementation on Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: chromium niacinate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexmedetomidine for Ulnar Nerve Block.
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Dexmedetomidine perineurally|DRUG: Ropivacaine 5mg/ml|DRUG: Ropivacaine 7.5mg/ml|DRUG: Dexmedetomidine systemically|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: PROCEDURE: Aim 2 Exercise group|PROCEDURE: Aim 1 Exercise Dosing|PROCEDURE: Aim 2 Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY
Status: COMPLETED
Conditions: Taste Disorder, Primary, Sweet
Interventions: DIETARY_SUPPLEMENT: lactisole|OTHER: mixed liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Analysis of Vitamin B6 in Sepsis
Status: COMPLETED
Conditions: Sepsis|Vitamin B6|Kidney Injury|Inflammatory Response|Oxidative Stress Response
Interventions: DRUG: vitamin B6|DRUG: 0.9% sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Real World Study of Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
Status: COMPLETED
Conditions: Gastric Cancer|Helicobacter Pylori Infection|Bismuth
Interventions: DRUG: Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transforming Health and Resilience In Vulnerable Environments: Mental Health, Psychosocial Support, and Climate-Smart Farming in Nakivale
Status: NOT_YET_RECRUITING
Conditions: Psychological Distress|Malnutrition, Child|Dietary Deficiency|Mental Health|Malnutrition
Interventions: BEHAVIORAL: Home Gardening Intervention (HGI)|BEHAVIORAL: Self-Help Plus (SH+)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of a Vaccine Prepared From Dendritic Cells Combined With Tumor Cells to Treat Advanced Kidney Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Allogeneic DCs and Autologous RCC Tumor Derived Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Patients With Localized, Primary GIST After Complete Surgery and With High Risk of Recurrence
Status: TERMINATED
Conditions: Gastro-Intestinal Stromal Tumour
Interventions: DRUG: Masitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Fluticasone Propionate 100mcg/Salmeterol 50 mcg Inhalation Powder to Advair Discus 100/50
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Test Product|DRUG: Reference Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anidulafungin Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ADOPT)
Status: COMPLETED
Conditions: Obesity Morbid
Interventions: DRUG: Anidulafungin 100mg single dose iv
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Follow-up of the Patients Included in the EXESAS Study
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Sleep Apnea, Obstructives
Interventions: OTHER: Training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE