pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Invasive Breast Carcinoma|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Akt Inhibitor GSK2141795|OTHER: Laboratory Biomarker Analysis|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy to Improve Feeding Skills in Preterm Infants
Status: ENROLLING_BY_INVITATION
Conditions: Premature Birth|Parenteral Nutrition|Motor Disorders|Neurodevelopmental Disorders|Sucking Behavior
Interventions: OTHER: Neurodevelopmental stimulation + Oral stimulation|OTHER: Oral stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Observe Clinical Effectiveness of Canagliflozin 300 mg Containing Treatment Regimens in Indian Type 2 Diabetes Participants With BMI>25 kg/m^2, in Real World Clinical Setting
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 300 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study of RGT-419B in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer or Other Solid Tumors
Status: RECRUITING
Conditions: Breast Cancer|Advanced Solid Tumor
Interventions: DRUG: RGT-419B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Postoperative Intravenous Parecoxib Sodium Followed by Oral Celecoxib in Osteoarthritis Patients
Status: COMPLETED
Conditions: Pain|Inflammation
Interventions: DRUG: Parecoxib and Celecoxib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sertraline for Preventing Post-stroke Depression and Improving Rehabilitation Outcomes
Status: TERMINATED
Conditions: Cerebrovascular Accident|Depression
Interventions: DRUG: sertraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of NODAT in Kidney Transplant Patients Receiving Belatacept Versus Standard Immunosuppression
Status: UNKNOWN
Conditions: New Onset Diabetes After Transplant|Kidney Transplantation
Interventions: DRUG: Belatacept|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Inguinal Hernia Operation and Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Inguinal Hernia|Quality of Life
Interventions: PROCEDURE: Adhesix mesh|PROCEDURE: Progrip mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study for Pleurodesis With Silver Nitrate in Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Malignant Pleural Effusion
Interventions: DRUG: Silver Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in Prostate Cancer Patients
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Immunotherapy allogeneic GM-CSF secreting cellular vaccine|DRUG: Chemotherapy (docetaxel and prednisone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Possible Effects of Diet Supplementation With Essential Fatty Acids in Chocolate Craving Volunteers
Status: COMPLETED
Conditions: Addictive Behavior|Abstinence Syndrome
Interventions: DRUG: Flaxseed oil|DRUG: Paraffin + # 2 dye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Supplemented Against Skin Reactivity
Status: COMPLETED
Conditions: Skin Sensitivity|Trans-epidermal Water Loss|Clinical Score|Assessment of Skin Moisturization Factors|Assessment of Serum Immune-regulatory Cytokine|Evaluation of Intestinal Flora Composition
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei NCC 2461 and Bifidobacterium longum NCC3001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Evaluation for Upper Extremity Lymphedema (BioBridge)
Status: RECRUITING
Conditions: Lymphedema|Edema
Interventions: DEVICE: BioBridge® Collagen Matrix|PROCEDURE: Vascularized Lymph Node Transfer (VLNT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Nasopharynx|Squamous Cell Carcinoma of Oropharynx|Squamous Cell Carcinoma of Hypopharynx
Interventions: DEVICE: Low Level Laser Therapy- (DMC, São Paulo, Brazil)|DEVICE: Placebo (DMC, São Paulo, Brazil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Safety and Efficacy of the Combination of Candenizumab, Lenvatinib, and SOX Regimen in the Treatment of HER2 Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Patients
Status: RECRUITING
Conditions: Overall Response Rate
Interventions: DRUG: Combination of Cardonizumab with Lenvatinib and SOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Prostate Biopsy Results With Biomarkers and mpMRI.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: mpMRI|DIAGNOSTIC_TEST: Urine and plasma biomarkes.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery
Status: UNKNOWN
Conditions: Congenital Heart Disease
Interventions: DRUG: Histidine Tryptophan Ketoglutarate Solution|OTHER: Terminal Warm Blood Cardioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma
Status: RECRUITING
Conditions: Recurrent High Grade Glioma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Glioblastoma|Gliosarcoma
Interventions: DRUG: PCI 24781|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With R/R B-NHL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Primary Mediastinal Large B Cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: epcoritamab (monotherapy)|BIOLOGICAL: epcoritamab|DRUG: rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone|DRUG: gemcitabine and oxaliplatin|BIOLOGICAL: epcoritamab (maintenance)|DRUG: rituximab and lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Hypertension
Interventions: DRUG: NX1011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a SGLT2 Inhibitor on Glucose Flux, Lipolysis and Exercise in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: IMP oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reducing Vertical Transmission of Hepatitis B in Africa
Status: RECRUITING
Conditions: Hepatitis B Infection
Interventions: DRUG: Tenofovir Disoproxil Fumarate|DRUG: Lamivudine Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brain-Health Lifestyle Restructuring Intervention
Status: UNKNOWN
Conditions: Lifestyle|Cognitive Decline|Aging
Interventions: BEHAVIORAL: Lifestyle Intervention|BEHAVIORAL: social activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: Fluorine F 18 Fluorodopa|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Safety, Pharmacokinetics and Pharmacodynamics of Different Doses of BIWH 3 in Patients With Chronic Critical Limb Ischaemia
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: BIWH 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: D-cycloserine Augmentation of Cognitive Remediation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: D-cycloserine|DRUG: Placebo|BEHAVIORAL: Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Body Weight Change|Schizophrenia|Schizoaffective Disorder|Psychotic Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Daewon-ES(B) & Megace in Healthy Male Volunteers Under Fasting and Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Megace|DRUG: DW-ES(B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety Evaluation of MR-guided Focused Ultrasound Treatment for Palliative Pain Control of Bone Metastases
Status: UNKNOWN
Conditions: Magnetic Resonance Guided Interventional Procedures
Interventions: DEVICE: magnetic resonance-guided focused ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIL62 Combined With Lenalidomide Versus Lenalidomide for Patients With Rituximab Refractory Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma and Marginal Zone Lymphoma
Interventions: DRUG: Recombinant Humanized Monoclonal Antibody MIL62, lenalinomide|DRUG: lenalinomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Of Pazopanib With Either Erlotinib Or Pemetrexed In Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: pazopanib|DRUG: erlotinib|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Satisfaction and Treatment Adherence of Diabetic Women Through the Use of FGM
Status: RECRUITING
Conditions: Gestational Diabetes|Gestational Diabetes Mellitus in Pregnancy
Interventions: DEVICE: Flash Glucose Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of and Immune Response to the Experimental Preventive HIV Vaccine, EP HIV-1090, in Healthy, HIV-1 Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: EP HIV-1043|BIOLOGICAL: EP HIV-1090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of E2609 on QTc Interval in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Placebo|DRUG: E2609|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Participating in Tai Chi to Reduce Anxiety and Keep up Physical Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Tai Chi Prehabilitation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Early Oral Intake of Different Types of Diets Affecting Gastrointestinal Function
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section
Interventions: DIETARY_SUPPLEMENT: water|DIETARY_SUPPLEMENT: juice/sport drink group|DIETARY_SUPPLEMENT: Chewing gum group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Ruxolitinib and Peg-interferon Alpha-2a Combination in Patients With Primary Myelofibrosis RUXOPeg
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolotinib|DRUG: peg-IFN alpha -2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occlusal Adjustment Time and Volume for Single Unit Fixed Prosthesis Fabricated With Different Virtual Mounting
Status: UNKNOWN
Conditions: Dental Occlusion|Crowns
Interventions: PROCEDURE: Digitized Mounted Articulator Scan|PROCEDURE: Average Positioning on Virtual Bonwill Triangle|PROCEDURE: Digital Face Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Muscle Energy Techniques in the Treatment of Chronic Non-specific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: OTHER: Muscle Energy Technique plus Conventional Physical Therapy|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine (ADACEL®) as a Booster in Adolescents
Status: COMPLETED
Conditions: Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: (ADACEL®): Tetanus, Reduced Diphtheria Toxoid and Acellular Pertussis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contrast-Enhanced Ultrasound Identification of Sentinel Nodes in Esophageal Cancer
Status: COMPLETED
Conditions: Esophagus
Interventions: PROCEDURE: Endoscopic Ultrasound-Guided Fine-Needle Aspiration (EUS-FNA)|PROCEDURE: Contrast-Enhanced Ultrasound|PROCEDURE: Fine-Needle Aspiration|DRUG: Sonazoid (Perflubutane)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Individualized Anti-Cancer Vaccine in Advanced Hepatocellular Carcinoma Subjects
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AlloVax|BIOLOGICAL: AlloStim|BIOLOGICAL: CRCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
Status: RECRUITING
Conditions: Tobacco Use Disorder
Interventions: DRUG: Clavulanic Acid|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: SCAI-001 0.01% eyedrop|DRUG: SCAI-001 0.02% eyedrop|DRUG: Restasis 0.05% eyedrop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Recovery After Left Lateral Hepatic Sectionectomy: Laparoscopic Versus Open Surgery.
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastasis|Liver Disease
Interventions: PROCEDURE: laparoscopic left lateral hepatic sectionectomy|PROCEDURE: open left lateral hepatic sectionectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Functional Assessment of Ashwagandaha Root Extract During Weight Loss
Status: COMPLETED
Conditions: Stress Reaction|Sleep Disturbance|Craving|Obesity
Interventions: DIETARY_SUPPLEMENT: Ashwagandha Root Extract Capsule|OTHER: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intra-articular Hyaluronan After Arthroscopic Meniscal Surgery
Status: COMPLETED
Conditions: Arthroscopic Meniscal Surgery
Interventions: DEVICE: Hyaluronan (0.5%, 5 mg/10 ml)|PROCEDURE: Standard arthroscopic meniscal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
Status: COMPLETED
Conditions: Kidney Stone
Interventions: DRUG: Flowmax|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Functional Chewing Gum in Reduction of Gingival Inflammation
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Functional Chitosan Chewing Gum|DEVICE: Control Chewing Gum|BEHAVIORAL: Oral hygiene measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Peripheral and Coronary Endothelial Dysfunction In Type 2diabetic Patients- Role of Metformin
Status: TERMINATED
Conditions: Coronary and Peripheral Endothelial Dysfunction
Interventions: DRUG: Metformin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: First-in-human Evaluation of the SELUTION DCB, a Novel Sirolimus Coated Balloon in Peripheral Arteries
Status: COMPLETED
Conditions: Patients With Peripheral Artery Disease in the SFA or PA
Interventions: DEVICE: SELUTION DCB (sirolimus coated balloon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension Study of INBRX-101 in Adults With AATD Emphysema
Status: RECRUITING
Conditions: Alpha 1-Antitrypsin Deficiency|Emphysema
Interventions: DRUG: INBRX-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocolytic Therapy in Conservative Management of Symptomatic Placenta Previa
Status: COMPLETED
Conditions: Placenta Previa
Interventions: DRUG: Placebo|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial for Comparison Of Intravenous Carbeitocin Versus Oxytocin In Management Of Placental Delivery In Second Trimester Interruption
Status: UNKNOWN
Conditions: CARBETOCIN FOR PREVENTION OF PLACENTAL RETAINED
Interventions: DRUG: Carbetocin|DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock
Status: COMPLETED
Conditions: Early Phase of Severe Sepsis and Septic Shock
Interventions: DRUG: Piperacillin-tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Coronary Artery Disease|Obstructive Sleep Apnea of Adult
Interventions: OTHER: OSA|OTHER: Non-OSA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fasting Study of Anagrelide Hydrochloride Capsules 1 mg to Agrylin® Capsules 1 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Anagrelide Hydrochloride Capsules 1 mg|DRUG: Agrylin® Capsules 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Comparing Pursestring Wound Closure vs Conventional Closure to Reverse Stoma of Colorectal Cancer Patients
Status: NO_LONGER_AVAILABLE
Conditions: Colorectal Cancer|Stoma Closure Technic
Interventions: PROCEDURE: Pursestring Wound Closure|PROCEDURE: Conventional Wound Closure|DEVICE: prolene
Study Type: EXPANDED_ACCESS
Clinical trial: A Study to Observe the Safety and Efficacy of Vedolizumab in Biologically Naive Participants With Ulcerative Colitis (UC) or Crohn´s Disease (CD)
Status: COMPLETED
Conditions: Crohn Disease|Colitis, Ulcerative|Inflammatory Bowel Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: muromonab-CD3|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous lymphocytes|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remote Ischemic Preconditioning on Physical Performance and Exertional Rhabdomyolysis
Status: UNKNOWN
Conditions: Physical Performance|Rhabdomyolysis
Interventions: PROCEDURE: RIPC intervention exposure|PROCEDURE: placebo intervention exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Investigate the Safety and Pharmacokinetic Characteristics of LC28-0126 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LC28-0126|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: OmegaD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of Hexaminolevulinate (HAL) Photodynamic Therapy (PDT) to Treat Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: HAL 5% with illumination|DRUG: HAL 1% with illumination|DRUG: HAL 0.2% with illumination|DRUG: Placebo ointment without illumination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Clinical Usability Study for the Recovery Force DVT II Cuff
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Venous Thrombosis
Interventions: DEVICE: Deep Vein Thrombosis (DVT) Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina
Status: COMPLETED
Conditions: Health|Vulvovaginal Candidiasis
Interventions: DRUG: Miconazole nitrate|PROCEDURE: Magnetic resonance imaging|BEHAVIORAL: Moderate levels of exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 1a Study of Thymosin Beta 4 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Recombinant Human Thymosin β4|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of NeuFlex and Swanson Metacarpophalangeal Implants for Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DEVICE: NeuFlex metacarpophalangeal implant|DEVICE: Swanson metacarpophalangeal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Left Versus Right Radial Artery and Radiation Exposure in Patients With Predictors of Trans-radial Failure
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Randomized left versus right radial artery approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Speed, Endurance and Balance in Women Patients With Multiple Sclerosis After 4 & 8 Weeks of Aquatic Exercise Training
Status: COMPLETED
Conditions: Multiple Sclerosis|Aquatic|Exercise
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia in Remission|Myelodysplastic Syndromes|Other Acute Leukemias
Interventions: BIOLOGICAL: Unmanipulated Umbilical Cord Blood (UCB)|BIOLOGICAL: AB-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Laser treatment|PROCEDURE: Mucosal flap surgery|BEHAVIORAL: Oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC)
Status: UNKNOWN
Conditions: Colorectal Cancer|Metastasis
Interventions: DRUG: Sunitinib Malate|DRUG: TAS 102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Therapy on Self-Esteem and Quality of Life in Patients With Stoma
Status: COMPLETED
Conditions: Stoma Colostomy|Stoma Ileostomy
Interventions: BEHAVIORAL: Laughter Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multidisciplinary Treatment of Chronic Vulvar Pain
Status: RECRUITING
Conditions: Vulvodynia|Chronic Pain
Interventions: COMBINATION_PRODUCT: Multidisciplinary treatment|COMBINATION_PRODUCT: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Sinusitis|Nasal Polyposis
Interventions: DEVICE: MEDIHONEY®|DRUG: Budesonide|DRUG: Normal saline sinus rinse|DRUG: Prednisone|PROCEDURE: Endoscopic sinus surgery|DRUG: nasal saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy
Status: TERMINATED
Conditions: Pain|Analgesia|Hernia, Inguinal
Interventions: DRUG: Gabapentin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of rTMS and tDCS Copuled With Robotic Therapy In Patients With Stroke
Status: UNKNOWN
Conditions: Chronic Stroke
Interventions: OTHER: active rTMS|OTHER: sham rTMS|OTHER: active tDCS|OTHER: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of 4CMenB (Bexsero®) to Prevent Gonorrhoea Infection in Gay and Bisexual Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Neisseria Gonorrheae Infection
Interventions: BIOLOGICAL: 4CMenB vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Painless Local Infiltration Anesthesia
Status: COMPLETED
Conditions: Varicose Veins|Pain|Surgery|Anesthesia
Interventions: DRUG: Mepivacaine chlorhydrate 2% in Sodium Bicarbonate 1.4%|DRUG: Mepivacaine chlorhydrate 2% with epinephrine in NS 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant (MK-0517, EMEND® IV) In Salvage Treatment of Chemotherapy-Induced Vomiting (MK-0517-030)
Status: TERMINATED
Conditions: Nausea|Vomiting
Interventions: DRUG: Fosaprepitant dimeglumine|DRUG: 5-HT3 RA|DRUG: Dexamethasone|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Orotracheal Intubation in Adult Patients: A Comparison of Standard Airtraq , Nasotracheal Airtraq Combined With a Stylet Inserted Endotracheal Tube and Standard Airtraq Combined Fiberoptic Intubation
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: Airtraq + fiberoptic|DEVICE: Airtraq|DEVICE: Nasotracheal Airtraq + styletted tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ibodutant for Relief of Irritable Bowel Syndrome With Diarrhoea (IBS-D)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DRUG: Ibodutant|DRUG: Ibodutant|DRUG: Ibodutant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine in Preventing Myalgia and/or Arthralgia in Patients Who Are Receiving Paclitaxel For Cancer
Status: TERMINATED
Conditions: Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: glutamine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Proteomic Profiling in Diagnosing Non-Small Cell Lung Cancer in Patients Who Are Undergoing Lung Resection for Suspicious Stage I Lung Lesions
Status: COMPLETED
Conditions: Lung Cancer
Interventions: GENETIC: proteomic profiling|OTHER: surface-enhanced laser desorption/ionization-time of flight mass spectrometry|PROCEDURE: biopsy|PROCEDURE: surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY900014 Formulation in Participants With Type 1 Diabetes Mellitus Using Insulin Pumps
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Bleeding|Novel Anti-platelets|Ticagrelor|Clopidogrel
Interventions: DRUG: Ticagrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Pulmonary Vein Isolation Using SmartTouch® Catheter With or Without Real-time Contact Force Data
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Fibrillation Ablation|Pulmonary Vein Isolation
Interventions: PROCEDURE: Pulmonary vein isolation using contact force sensing catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Both Column Fixation Corridor in Pelvic Surgery
Status: COMPLETED
Conditions: Acetabular Fractures
Interventions: PROCEDURE: Virtual placement of lag screws in both columns of the acetabulum on 3D pelvic CT models.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: 40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Technology-Delivered Interventions for Smoking in Pregnancy: The Mommy Check-Up Study.
Status: UNKNOWN
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Referral to SmokeFreeMoms, Quitline or Brief intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane
Status: RECRUITING
Conditions: Acute Kidney Injury Due to Sepsis
Interventions: DEVICE: oXiris membrane|DEVICE: Polysulfone membrane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fetal Cystoscopy Versus Vesico-amniotic Shunting in Severe Lower Urinary Tract Obstructions
Status: UNKNOWN
Conditions: Lower Urinary Tract Obstructive Syndrome
Interventions: PROCEDURE: CYSTO|PROCEDURE: Vesico-amniotic shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO)
Status: COMPLETED
Conditions: Pregnancy|Depression
Interventions: DIETARY_SUPPLEMENT: Omega-3 polyunsaturated fatty acids|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Family Support on Diabetes Patients' Health Beliefs, Behavioral and Metabolic Results
Status: COMPLETED
Conditions: Family Members|Diabetes Mellitus
Interventions: BEHAVIORAL: Diabetes Education Program Based on Health Belief Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Celecoxib and Capecitabine Combined With Pelvic Irradiation in Treating Patients With Stage II or Stage III Adenocarcinoma (Cancer) of the Rectum
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: celecoxib|RADIATION: radiation therapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing 3D Printed Personalized Aortic Lesion Models in Preoperative Assessment
Status: RECRUITING
Conditions: Aortic Aneurysm
Interventions: OTHER: historical control|OTHER: 3D printed lesion model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Acceptability of a Telehealth Intervention Among Women With Perinatal Mental Health
Status: NOT_YET_RECRUITING
Conditions: Perinatal Depression|Perinatal Anxiety|Substance Use|Telehealth
Interventions: BEHAVIORAL: UPLIFT program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Age of Red Blood Cells in Premature Infants Study (ARIPI)
Status: COMPLETED
Conditions: Premature Birth
Interventions: BIOLOGICAL: Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Versus Sequential Antiretroviral Therapy (ARV) Therapy and Mycobacterium Tuberculosis (MTB) Treatment
Status: TERMINATED
Conditions: HIV|AIDS|Tuberculosis
Interventions: DRUG: Simultaneous ARV and antiMTB|DRUG: Deferred RV and antiMTB treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study Of Valdecoxib 5 Mg, 10 Mg, And 20 Mg Once Daily Versus Placebo In Patients With Osteoarthritis Of The Knee (Japan)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: valdecoxib|DRUG: valdecoxib|DRUG: valdecoxib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Raltegravir-Based Antiretroviral Therapy in HIV-HCV Coinfected Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation|HIV Infections|Antiretroviral Therapy
Interventions: OTHER: Raltegravir-based antiretroviral therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-913 in Subjects With MPS II
Status: TERMINATED
Conditions: Mucopolysaccharidosis II|MPS II
Interventions: BIOLOGICAL: SB-913
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Therapy in Acute Coronary Syndromes and Coronary Artery Ectasia
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Coronary Artery Ectasia
Interventions: DRUG: Rivaroxaban 15 MG|DRUG: Acetylsalicylic acid 100mg|DRUG: Clopidogrel 75 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ixazomib and Dexamethasone Refractory Autoimmune Cytopenia
Status: WITHDRAWN
Conditions: Immune Thrombocytopenia|Warm Autoimmune Hemolytic Anemia
Interventions: DRUG: Ninlaro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vopratelimab (JTX-2011) Alone and in Combination With Anti-Programmed Cell Death Protein 1 (PD-1) or Anti-Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) in Subjects With Advanced and/or Refractory Solid Tumors
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: Vopratelimab|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage
Status: COMPLETED
Conditions: Reduction of Small Intestinal Ulceration Risk
Interventions: DIETARY_SUPPLEMENT: Bif195|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo Compared to "Standard of Care" Basal Insulins in Insulin Naïve Patients Initiating Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine (U300)|DRUG: insulin glargine (U100)|DRUG: NPH insulin|DRUG: insulin detemir|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofloxacin Concentration-toxicity Relationship in the Elderly
Status: RECRUITING
Conditions: Ofloxacin|Bone and Joint Infection|Therapeutic Drug Monitoring|Adverse Drug Reactions
Interventions: DRUG: ofloxacin|OTHER: questionnaire|BIOLOGICAL: Ofloxacin Serum concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KN046 Plus Lenvatinib in Subject With Advanced Non-Small Cell Lung Cancer in the Failure of Anti-PD-(L)1 Agent
Status: TERMINATED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: KN046|DRUG: Lenvatinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lenalidomide Maintenance in Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma: a Phase II, Open-label, Single-arm Study
Status: NOT_YET_RECRUITING
Conditions: Primary Central Nervous System Lymphoma and Primary Vitreoretinal Lymphoma
Interventions: RADIATION: intensity-modulated radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint Infection
Status: NOT_YET_RECRUITING
Conditions: Prosthetic Joint Infections of Hip|Staphylococcus Aureus Infection
Interventions: BIOLOGICAL: Phage therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide Extended-release for Injectable Suspension, 1 mg|DRUG: Semaglutide Extended-release for Injectable Suspension, 4 mg|DRUG: Semaglutide Extended-release for Injectable Suspension, 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: BIOLOGICAL: anti-GPC3 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biventricular Pacing in Children With Congenital Heart Disease
Status: COMPLETED
Conditions: Congenital Heart Disease (CHD)
Interventions: DEVICE: Biventricular Pacing (BiVp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioural Insights to Improve Take up of SRH Services (Uganda)
Status: UNKNOWN
Conditions: Health Behavior
Interventions: OTHER: e-Coupon Text Modification and Reminders|OTHER: e-Coupon standard text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn
Status: COMPLETED
Conditions: Pulmonary Hypertension, Familial Persistent, of the Newborn
Interventions: DRUG: placebo|DRUG: iv sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT