pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: Needle-Free Jet Injection of 1 % lidocaine|OTHER: traditional needle infiltration of 1% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dead Space Closure With Quilting Suture Versus Conventional Closure With Drainage
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Quilting suture without drainage|PROCEDURE: Conventional closure with drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Stress Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase.
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Leukaemia During Therapy With L - Asparaginase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of PER-001 in Participants With Diabetic Retinopathy
Status: RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DRUG: PER-001 Intravitreal Implant - Low Dose|DRUG: PER-001 Intravitreal Implant - High Dose|DRUG: PER-001 Intravitreal Implant - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Comparing Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL) and Multiple Sclerosis Quality of Life-54 Instrument (MSQOL-54) in Relapsing Multiple Sclerosis (RMS) Patients on Long-term Rebif® Therapy
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research Evaluating the Value of Augmenting Medication With Psychotherapy
Status: COMPLETED
Conditions: Depression|Depressive Disorder
Interventions: BEHAVIORAL: Brief Supportive Psychotherapy|BEHAVIORAL: CBASP|DRUG: Medication Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Evaluate the Haemonetics POLFA Modified Sample Needle Assembly With Vacuum Tube Holder
Status: COMPLETED
Conditions: Transmission, Blood, Recipient/Donor
Interventions: DEVICE: POLFA (Needle Assembly)|DEVICE: Kawasumi (Needle Assembly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Educating QUitline Callers About Lung Cancer Screening
Status: COMPLETED
Conditions: Population at Risk
Interventions: BEHAVIORAL: Should I Screen website|BEHAVIORAL: Should I Screen print booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Musculoskeletal and Connective Tissue Diseases
Interventions: BIOLOGICAL: Adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 601 Versus Ranibizumab in Patients With Pathological Myopic Choroidal Neovascularization (pmCNV)
Status: UNKNOWN
Conditions: Pathological Myopic Choroidal Neovascularization
Interventions: DRUG: 601|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Growth Hormone Treatment in Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis|Still Disease, Juvenile-Onset
Interventions: DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Refractory Malignant Solid Neoplasm|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: Cediranib|DRUG: Cediranib Maleate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Selumetinib|DRUG: Selumetinib Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol-ROC-Training
Status: RECRUITING
Conditions: Binge Drinking|Heavy Drinking|Young Adult|Heavy Drinker
Interventions: BEHAVIORAL: Mindfulness-Based Treatment-Regulation of Craving|BEHAVIORAL: Cognitive-Based Therapy-Regulation of Craving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Validation Study of Bioelectronics
Status: RECRUITING
Conditions: Healthy|Health Behavior
Interventions: DEVICE: Multi-modality Noninvasive Biosensor|DEVICE: Oximeter|DEVICE: Portable Blood Pressure Monitor|DEVICE: Vicorder Pulse Wave Velocity Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized, Multicenter, Evaluator-Blinded, Active-Controlled, Parallel-Group Investigation to Evaluate the Performance and Safety of YVOIRE® Classic Plus Versus Comparator for Temporary Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Correction of Nasolabial Folds
Interventions: DEVICE: Hyaluronic acid dermal filler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Brain Protection Effects of the Green Tea Extract Theaphenon 95% (95% Pure EGCG) in Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: DRUG: 95% Pure ECGC capsules 200mg|DRUG: Placebo Comparator:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: bevacizumab|DRUG: cytarabine|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Hyaluronic Acid (HA) Product for Cheek Augmentation
Status: TERMINATED
Conditions: Facial Tissue Augmentation
Interventions: DEVICE: HA experimental|DEVICE: HA comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Symbicort Versus Its Monocomponents - SPRUCE 80/4.5
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol|DRUG: budesonide|DRUG: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cigar Box Arthroscopy: A Study of Non-Anatomic Arthroscopy Training
Status: COMPLETED
Conditions: Simulation Training
Interventions: OTHER: Non-Anatomic Arthroscopy Simulation|OTHER: Anatomic Arthroscopy Simulation|OTHER: Pre-assesment education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Evaluate the Efficacy of Gene Therapy for Pyruvate Kinase Deficiency
Status: NOT_YET_RECRUITING
Conditions: Pyruvate Kinase Deficiency
Interventions: BIOLOGICAL: RP-L301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Food Effect Study of Cenobamate as an Oral Suspension and Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cenobamate 200Mg Tab Fasted|DRUG: Cenobamate Oral Suspension Fed|DRUG: Cenobomate Oral Suspension Fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cipro Inhaler for Cystic Fibrosis Children Ages 6-12
Status: COMPLETED
Conditions: Pseudomonas Infection
Interventions: DRUG: Ciprofloxacin (Cipro, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levosimendan In Patients Undergoing LVAD Implantation
Status: UNKNOWN
Conditions: Left Ventricular Dysfunction|Right Ventricular Dysfunction|Biventricular Failure
Interventions: DRUG: Levosimendan 2.5 MG/ML Injectable Solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TENDOSHOCK-2010 Combination Therapy for Athletic Tendinopathies
Status: UNKNOWN
Conditions: Tendinopathy|Epicondylitis
Interventions: DRUG: Polidocanol|DEVICE: Focused extracorporeal shock wave therapy|DRUG: Topical NO|BEHAVIORAL: Painful eccentric training in Achilles tendinopathy|BEHAVIORAL: Painful eccentric training for patella tendinopathy on 25° decline board|BEHAVIORAL: Painful eccentric training for elbow tendinopathy using Thera-Band Flex-Bar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nursing Interventions on Maternal Attachment, Parental Self-efficacy and Infant Development
Status: COMPLETED
Conditions: Nurse's Role|Parenting|Self Efficacy|Development, Child|Attachment
Interventions: OTHER: Nursing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Care in Term Neonates: The Role of Wondaleaf Adhesive Pouch (WLAP)
Status: COMPLETED
Conditions: Umbilical Cord Infection|Umbilical Sepsis|Neonatal Sepsis
Interventions: DEVICE: Adhesive pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Viscocanalostomy, Phacoemulsification, OIogen Implant in Open Angle Glaucoma
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma
Interventions: PROCEDURE: combined phacoemulsification and viscocanalostomy|PROCEDURE: combined phacoemulsification and viscocanalostomy and ologen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Status: RECRUITING
Conditions: Geographic Atrophy
Interventions: DRUG: JNJ-81201887|DRUG: Prednisone|OTHER: Placebo|DRUG: Triamcinolone|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Carbohydrate and Plant-Based Dietary Effects on Vascular Health
Status: COMPLETED
Conditions: Heart Disease, Ischemic|Hyperlipidemias|Hypertension
Interventions: OTHER: Whole-Food, Plant-Based Diet and Low-Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS)
Status: UNKNOWN
Conditions: Apnea|Snoring
Interventions: DRUG: Polidocanol Sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preventing Urinary Tract Infections With E. Coli Nissle:
Status: RECRUITING
Conditions: Urinary Tract Infections in Children|Secondary Prevention
Interventions: DRUG: E. coli Nissle|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fu's Subcutaneous Needling Treatment for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Fu's subcutaneous needling(FSN)|PROCEDURE: Transcutaneous Electric Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Multidose Preservative-free Lubricating Eye Drops Contained in Novelia® Eye Dropper in Non-Contact Lens Wearing Patients
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Investigational Lubricating Eye Drop in a Novelia® bottle|DRUG: Blink® Tears eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Early Stage, Low Volume Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: OTHER: Prostate Biopsy, Focal Brachytherapy , Assessment of QOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nutrition Training Augmented With Digital Technology in Graduate Medical Education
Status: COMPLETED
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Nutri Training|BEHAVIORAL: Standard Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Toripalimab Combined With Axitinib as Neoadjuvant Therapy for Advanced/Metastatic Non-clear Cell Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Neoadjuvant Therapy|Advanced Cancer|Metastatic Kidney Cancer
Interventions: DRUG: Toripalimab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Muscle Function in Nutritionally at Risk, Elderly Patients
Status: WITHDRAWN
Conditions: Muscle Weakness|ICU-acquired Weakness
Interventions: DIETARY_SUPPLEMENT: HMB protein supplement (3g)|DIETARY_SUPPLEMENT: Nutritional Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DEVICE: Transcranial ExAblate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Group Program for Type 2 Diabetes Mellitus (T2DM)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Integrative Group Program|OTHER: Conventional treatment for T2DM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Therapeutic Percutaneous Electrolysis in Achilles Tendinopathy.
Status: RECRUITING
Conditions: Electrolysis|Achilles Tendinopathy|Ultrasonography|Physical Therapy
Interventions: OTHER: Sham comparator|OTHER: Experimental group 1|OTHER: Experimental group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Virtual Reality Glasses Use During Inhaler Treatment in Children
Status: COMPLETED
Conditions: Bronchiolitis|Anxiety
Interventions: DEVICE: Virtual Reality audio and visual glass (Roller Coasters, group 1)|DEVICE: Virtual Reality audio and visual glass (Wild Dolphins, group 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single and Multiple Ascending Dose Study With EP395
Status: COMPLETED
Conditions: Adult ALL
Interventions: DRUG: EP395|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical tRial of Endobronchial Ultrasound for the Diagnosis of MEDiastinal lymphadenopathY (REMEDY)
Status: UNKNOWN
Conditions: Isolated Mediastinal Lymphadenopathy|Sarcoidosis|Tuberculosis|Lung Cancer|Lymphoma
Interventions: PROCEDURE: EBUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Foot Center of Pressure Manipulation on Hip Osteoarthritis Patients During Gait
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DEVICE: AposTherapy Biomechanical System|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: SQ tree SLIT-tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Post-operative Diet in Children Following Tonsillectomy and Adenoidectomy
Status: UNKNOWN
Conditions: Chronic Tonsillitis|Sleep Disordered Breathing
Interventions: OTHER: Diet modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial of Erythrocyte Encapsulated Thymidine Phosphorylase In Mitochondrial Neurogastrointestinal Encephalomyopathy
Status: WITHDRAWN
Conditions: Mitochondrial Diseases|Metabolic Disease|Inborn Errors of Metabolism
Interventions: COMBINATION_PRODUCT: EE-TP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib Combined With Chemotherapy or Antiangiogensis in Patients With Bim Deletion or Low EGFR Mutation Abundance
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: pemetrexed or gemcitabine plus carboplatin,|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single IV Administration of TB-402 for Prophylaxis of Venous Thromboembolic Events (VTE) After Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Prophylaxis of Venous Thromboembolic Events
Interventions: DRUG: TB-402|DRUG: Rivaroxaban|DRUG: TB-402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumor|Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Perfusion Changes After Anti-VEGF Versus Targeted Retinal Photocoagulation in Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy|Vascular Endothelial Growth Factor Overexpression|Diabetic Retinopathy
Interventions: DRUG: Bevacizumab Injection|PROCEDURE: Targeted retinal photocoagulation|PROCEDURE: Standard pan-retinal photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early vs Late Urinary Catheter Removal After Renal Transplantation
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Kidney Transplant Infection|Urinary Fistula|Urinary Tract Infections|Urinary Catheter
Interventions: PROCEDURE: Urinary catheter removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Preliminary Efficacy of STI-1386 Oncolytic Virus in Relapsed or Refractory Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Cancer|Cancer of Pancreas|Sarcoma|Hepatic Metastasis|Solid Tumor
Interventions: DRUG: STI-1386
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Care of Complicated Appendicitis
Status: COMPLETED
Conditions: Appendicitis|Perforated Appendicitis|Ruptured Appendicitis|Complicated Appendicitis
Interventions: PROCEDURE: Early Appendectomy|PROCEDURE: Interval Appendectomy|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer|Breast Cancer|Abdominal Cancer|Pelvic Cancer
Interventions: DEVICE: Novel CBCT Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can Making Video Narratives Benefit Adolescents With Cancer
Status: WITHDRAWN
Conditions: Pediatric Cancer
Interventions: BEHAVIORAL: Video narrative|BEHAVIORAL: PedsQL|BEHAVIORAL: Ten Item Personality Inventory|BEHAVIORAL: Delis-Kaplan Executive Function System (D-KEFS) Verbal Fluency Test|BEHAVIORAL: The Cognitive Log
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Defining Beef and Meal Frequency as Key Components of a Healthy Eating Pattern for Muscle Health and Wellbeing
Status: UNKNOWN
Conditions: Meal Frequency|Dietary Habits|Muscle Protein Synthesis
Interventions: BEHAVIORAL: Animal-based Protein Foods|BEHAVIORAL: Skewed Protein Distribution|BEHAVIORAL: Plant-based Protein Foods|BEHAVIORAL: Balanced Protein Distribution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Plus Docetaxel and Capecitabine Versus Docetaxel and Capecitabine in the Treatment of Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Nimotuzumab|DRUG: docetaxel|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae
Status: RECRUITING
Conditions: Diarrhea|Wasting|Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: Lactoferrin|DIETARY_SUPPLEMENT: Lysozyme|COMBINATION_PRODUCT: Lactoferrin + Lysozyme|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Power Exercises Result in Superior Benefits for People With Patellofemoral Pain?
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Strength Training Group (STG)|OTHER: Strength and Power Training Group (SPTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iloprost in High Risk Cardiac Surgical Patients
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Iloprost (Ventavis)|DRUG: Isotonic Sodium Chloride solution 0.9 % (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: B/F/TAF|DRUG: TDF-based triple ART regimen switching to B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Intrauterine Adhesions After Hysteroscopic Metroplasty With Autocross-linked Hyaluronic Acid Gel
Status: UNKNOWN
Conditions: Intrauterine Adhesions|Septate Uterus
Interventions: PROCEDURE: Hysteroscopic metroplasty|DEVICE: Autocross-linked acid hyaluronic gel|PROCEDURE: Office second look hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Chemotherapy Combination With Autologous Cell Immunotherapy in the Recurrent and Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Bevacizumab Injection [Avastin]|DRUG: Oxaliplatin|DRUG: Capecitabine|BIOLOGICAL: PD1-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A CR-UK Phase I Trial of LY3143921
Status: ACTIVE_NOT_RECRUITING
Conditions: a. Colorectal Cancer|b. High Grade Serous Ovarian Cancer|c. Non Small-cell Lung Cancer (Squamous Cell Variant)|d. Squamous Carcinoma of the Oesophagus|e. Squamous Carcinoma of the Head and Neck (HPV Negative)|f. Urothelial Cancer|g. Breast Cancer (Triple Negative Type)|h. Pancreatic Cancer
Interventions: DRUG: LY3143921 hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Insomnia Treatment to Reduce Cardiovascular Risk in Patients With Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: Insomnia|Posttraumatic Stress Disorder|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Cognitive Behavior Therapy for Insomnia|BEHAVIORAL: Weekly phone contacts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exercise in Peripheral Artery Disease
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Intermittent Claudication
Interventions: OTHER: No intervention (Observational study)|OTHER: Control session|OTHER: Exercise session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pediatric Rotary File System Versus Hand Instrumentation for Root Canal Preparation in Primary Teeth
Status: COMPLETED
Conditions: Pulpitis
Interventions: DEVICE: rotary system|DEVICE: Manual files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on the Consequences of Weight Loss After Bariatric Surgery on Obese Patients' Spine.
Status: RECRUITING
Conditions: Low Back Pain in Obese Patients After Important Weight Loss
Interventions: DIAGNOSTIC_TEST: Full Spine Radiography|DIAGNOSTIC_TEST: Lumbar spine MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TYPE 2 HEPATORENAL SYNDROME
Status: COMPLETED
Conditions: Safety and Efficacy of Terlipressin and Noradrenaline and Predictive Factors of Response in Type 2 HRS
Interventions: DRUG: Noradrenaline|DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood
Status: COMPLETED
Conditions: Alternating Hemiplegia of Childhood
Interventions: DRUG: Triheptanoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Cefazolin 2g for Injection USP and Dextrose Injection USP|DRUG: Cefazolin 1.5g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BCG Combined With Tislelizumab for BCG-untreated Patients With High-risk Non-muscle Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-muscle-invasive Bladder Cancer
Interventions: DRUG: BCG combined with Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safeness of Trivalent Subunit Inactivated Influenza Vaccines in Preventing Flu on Vietnamese Volunteers
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Seasonal flu vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Telemedicine Influence in the Follow up of the Type 2 Diabetes Patient
Status: COMPLETED
Conditions: Type 2 Diabetes|Telemedicine|Self Monitoring Blood Glucose|Primary Care
Interventions: DEVICE: Telemedicine system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Non-small Cell Lung Cancer|Pancreatic Carcinoma|Triple-Negative Invasive Breast Carcinoma|Malignant Glioma of Brain|Colorectal Carcinoma|Gastric Carcinoma
Interventions: BIOLOGICAL: anti-MUC1 CAR-pNK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of an Integrated Positron Emission Tomography/Magnetic Resonance (PET/MR) System, Accessories and Components
Status: TERMINATED
Conditions: Indication for a PET CT Exam
Interventions: DEVICE: PET MR Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Do Educational Digital Films Enhance Patient COPD Outcomes?
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Pocket Medic|BEHAVIORAL: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Motion Exergaming Approach for Symptom Management: HNC
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: A personalized Physical Activity intervention with fitness graded Motion Exergames (PAfitME)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Contraceptive Efficacy and Body Weight
Status: COMPLETED
Conditions: Contraception|Body Weight
Interventions: DRUG: ethinyl estradiol / levonorgestrel|DRUG: ethinyl estradiol / levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of a Dissonance-Based Eating Disorder Prevention Program (The Body Project II)
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Dissonance-based eating disorder prevention program|BEHAVIORAL: Educational brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development of Advanced Leak Detection Technologies for Positive Airway Pressure Devices Therapies
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: Positive Airway Pressure (PAP) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Trial for Project SafeCare for Child Neglect
Status: COMPLETED
Conditions: Child Neglect
Interventions: BEHAVIORAL: SafeCare|OTHER: In vivo coached quality control|BEHAVIORAL: Services As Usual|OTHER: Uncoached
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compression and CO2 Laser for Leg Wounds
Status: ENROLLING_BY_INVITATION
Conditions: Wound Healing
Interventions: OTHER: Compression bandages|OTHER: Standard wound dressings|DEVICE: Fractional ablative carbon dioxide laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Enhancement Training Towards Elders Resilience to Aging
Status: COMPLETED
Conditions: Age-related Cognitive Decline
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-center Trial for Reinforced Staple During Distal Pancreatectomy
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: Endo GIA Reinforced Reload with Tri-Staple technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Dye Laser and Affirm Laser in the Treatment of Abdominoplasty Scars
Status: TERMINATED
Conditions: Abdominoplasty Scars
Interventions: DEVICE: pulsed dye laser|DEVICE: Affirm Laser|DEVICE: combined PDL and Affirm Lasers|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Secondary Malignancy
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukaemia|Multiple Myeloma
Interventions: BIOLOGICAL: Idecabtagene vicleucel|BIOLOGICAL: Lisocabtagene maraleucel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of IONM Between Remimazolam and Propofol
Status: COMPLETED
Conditions: Ossification Posterior Longitudinal Ligament|Cervical Spondylotic Myelopathy
Interventions: DRUG: Arm I (Propofol)|DRUG: Arm II (Remimazolam)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Comparing Vaginal Misoprostol and Intravenous Oxytocin for Induction of Labor
Status: COMPLETED
Conditions: Induction of Labor in Multiparous Women
Interventions: DRUG: Vaginal Misoprostol|DRUG: Intravenous Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manual Therapy Techniques on the Mobility of the Diaphragm in People With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: Experimental: Diaphragmatic Manual Therapy Group A|OTHER: Sham Breathing Retraining Exercises Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GFRC Enhance Patient Satisfaction and Reduce Complications in Maxillary Implants With Pekkton Frameworks
Status: NOT_YET_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: PROCEDURE: PROVISIONALIZATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disease-modifying Potential of Transdermal NICotine in Early Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DRUG: nicotine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Reduced Insulinotropic Effect of a Continuous Infusion Relative to a Bolus Injection of GIP
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: GIP Bolus|DRUG: GIP Clamp|PROCEDURE: Oral glucose tolerance test (OGTT)|PROCEDURE: hyperglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of the Community Popular Opinion Leader (C-POL) Model in Alabama
Status: COMPLETED
Conditions: Risk Behavior|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Community-Popular Opinion Leader Model|BEHAVIORAL: Diffusion of Innovations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Colorectal Cancer With Unresectable Liver Metastases
Status: TERMINATED
Conditions: Colorectal Neoplasms|Liver Neoplasms
Interventions: DRUG: Combination therapy of irinotecan with 5-FU, leucovorin plus bevacizumab in the neoadjuvant setting.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pudendal vs Caudal Block for Pediatric Penile Surgery
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Caudal Block|PROCEDURE: Pudendal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma
Status: COMPLETED
Conditions: CNS Lymphoma|CNS Brain Cancer|Non-Hodgkin's Lymphoma
Interventions: OTHER: Rituximab, Methotrexate, Vincristine, Procarbazine, PBPCs collection, Busulfan, Thiotepa, and Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Breath Nitrogen Washout in Healthy and Cystic Fibrosis Children
Status: COMPLETED
Conditions: Cystic Fibrosis|Healthy
Interventions: DEVICE: Comparison of two MBWN2 devices : "EasyOne Pro Lab" versus "Exhalyzer D"
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kinesthetic Exercises and Sine Sound Waves in Cervical Spondylosis
Status: COMPLETED
Conditions: Cervical Spondylosis
Interventions: PROCEDURE: Sine sound waves|PROCEDURE: Kinesthetic exercises|PROCEDURE: Sine sound waves plus kinesthetic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapamycin-Eluting Stents With Different Polymer Coating to Reduce Restenosis (ISAR-TEST-3)
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: rapamycin-eluting Stent with permanent polymer|DEVICE: rapamycin-eluting stent with biodegradable polymer|DEVICE: polymer-free, rapamycin-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between T LYmphocytes Depletion and Clinical Response to RITUXimab in Rheumatoid Arthritis (LYRITUX)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunotherapy in Recipients of Human Leukocyte Antigen (HLA)-Mismatched, Living Donor Kidney Transplants
Status: WITHDRAWN
Conditions: Kidney Transplant Rejection
Interventions: BIOLOGICAL: MDR-102|DRUG: Immunosuppressive Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Smoking Cessation and Menstrual Cycle Phase
Status: RECRUITING
Conditions: Nicotine Dependence|Tobacco Smoking|Smoking Cessation|Nicotine Use Disorder|Substance Use Disorders
Interventions: OTHER: Timing of nicotine replacement therapy start date|DRUG: Nicotine Replacement Therapy Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control Trial of Intermittent Hemodialysis With Regional Citrate VS Priming Heparin With Predilution in Patients at Risk of Bleeding
Status: COMPLETED
Conditions: Hemodialysis
Interventions: PROCEDURE: reduced systemic heparin anticoagulation|PROCEDURE: Regional Citrate Anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinic Treatment Project
Status: COMPLETED
Conditions: Anxiety|Depression|Problem Behavior
Interventions: BEHAVIORAL: psychotherapy|BEHAVIORAL: evidence-based treatment|BEHAVIORAL: modular evidence-based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Investigating the Effects of a Novel Weight Management Program
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Dietary Supplements and TR90 Eating Plan|DIETARY_SUPPLEMENT: Placebo and Low Fat Eating Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cefprozil for Oral Suspension 250 mg/5 mL, Non-fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefprozil for oral suspension 250 mg/5 mL|DRUG: CEFZIL® for Oral Suspension 250 mg/5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multi-domain and Multi-component Falls Intervention Program for Community- Dwelling Older Adults: SAFE-TECH
Status: NOT_YET_RECRUITING
Conditions: Fall Prevention|Fall Injury
Interventions: OTHER: Falls prevention intervention including exercise and educational components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Nicotine to Reverse Age-related Auditory Processing Deficits
Status: RECRUITING
Conditions: Auditory Perceptual Impairment|Aging
Interventions: OTHER: Nicotine gum|OTHER: Placebo gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Vitamin D Treatment in Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Vitamin D Deficiency|Primary Hyperparathyroidism|Hypercalcemia
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravascular Laser Irradiation of Blood for Osteoarthritis of Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Intravascular laser irradiation of blood|DEVICE: Intravascular laser irradiation of blood (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trans-Obturator Tape Versus Trans-Vaginal Tape for Stress Urinary Incontinence in Women
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: TVT Surgery TOT Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy
Status: RECRUITING
Conditions: Buruli Ulcer
Interventions: DRUG: Standard [RC8]: rifampicin plus clarithromycin (RC) therapy for 8 weeks.|DRUG: Investigational [RCA4]: standard (RC) plus amoxicillin/clavulanate (A) for 4 weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT