pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.
Status: RECRUITING
Conditions: Anxiety Disorders
Interventions: DRUG: sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tacrolimus Versus Cyclophosphamide as Treatment for Lupus Nephritis
Status: COMPLETED
Conditions: SLE|Lupus Nephritis|Renal Insufficiency|End-stage Renal Disease
Interventions: DRUG: Tacrolimus|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
Status: COMPLETED
Conditions: Parkinson's Disease|Multiple System Atrophy|Orthostatic Hypotension
Interventions: DRUG: Fludrocortisone|DRUG: Domperidone|BEHAVIORAL: Conservative Measures for Orthostatic Hypotension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mobile Otoscopy - Efficacy of Residents to Diagnose Acute Otitis Media Using a Smartphone Otoscope Attachment
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DEVICE: Cellscope|DEVICE: Traditional otoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Cohort Study of Conversion From Aranesp® to NESP® for the Treatment of Anemia in Dialysis Patients
Status: COMPLETED
Conditions: Anemia|End Stage Renal Failure on Dialysis
Interventions: OTHER: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Bipolar I Disorder
Interventions: DRUG: VHX-896 and iloperidone|DRUG: Iloperidone and VHX-896
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: DRUG: Topical Amphotericin-B 0.4% liposomal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia
Status: COMPLETED
Conditions: Post Stroke Aphasia
Interventions: DEVICE: rTMS (repetitive transcranial magnetic stimulation )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of McKenzie Exercises With And Without Mulligan Mobilization In Text Neck Syndrome.
Status: RECRUITING
Conditions: Neck Syndrome|Forward Head Posture
Interventions: OTHER: McKenzie Exercises without Mulligan Mobilization|OTHER: McKenzie Exercises with Mulligan Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short Term Oral Iron Supplementation in Systolic Heart Failure Patients Suffering From Iron Deficiency Anemia
Status: COMPLETED
Conditions: Heart Failure, Systolic|Iron-deficiency Anemia
Interventions: DRUG: Ferrous Sulfate|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) of the Nucleus Basalis of Meynert (NbM) in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Cognitive Deficit
Interventions: DEVICE: NBM-DBS|DEVICE: DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Efficacy, and Drug Levels of BMS-986369 in Participants With Relapsed or Refractory T-cell Lymphomas in Japan
Status: RECRUITING
Conditions: Relapsed or Refractory T-cell Lymphomas
Interventions: DRUG: BMS-986369
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin|GENETIC: RNA analysis|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: protein expression analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunohistochemistry staining method|OTHER: questionnaire administration|PROCEDURE: cognitive assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Transmyocardial Revascularization (TMR) With Bone Marrow Aspirate (BMAC) for Angina Reduction
Status: TERMINATED
Conditions: Angina
Interventions: BIOLOGICAL: Bone Marrow Aspirate Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Work And Vocational advicE Study - Effectiveness of Adding a Brief Vocational Support Intervention to Usual Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Pain|Mental Health Issue|Mental Health Disorder|Other Physical Health Condition|Absence
Interventions: BEHAVIORAL: Vocational Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Short Time Intervals in Split-Dose Bowel Preparation of Oral Sulfate Solution for Colonoscopy
Status: ENROLLING_BY_INVITATION
Conditions: Colonoscopy: Bowel Preparation
Interventions: DRUG: Magnesium Sulfate，Sodium Sulfate and Potassium Sulfate Concentrate Oral Solution|DRUG: Magnesium Sulfate，Sodium Sulfate and Potassium Sulfate Concentrate Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
Status: RECRUITING
Conditions: Sexual Dysfunction|Postmenopausal Symptoms|Pelvic Floor Muscle Weakness
Interventions: OTHER: Pelvic Floor Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome
Status: COMPLETED
Conditions: Appendicolith|Appendicitis|Appendicitis With Perforation|Appendicitis Peritonitis|Appendiceal Abscess|Appendicitis Acute
Interventions: PROCEDURE: 3D Laparoscopic Appendectomy|PROCEDURE: 2D Laparoscopic Appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: AVP-923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nasal HFOV Versus Nasal SIPPV in Neonate Following Extubation: RCT Crossover Study
Status: COMPLETED
Conditions: High-Frequency Ventilation|Intermittent Positive-Pressure Ventilation|Newborn Morbidity|Noninvasive Ventilation
Interventions: DEVICE: Non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Tolerability of ACT-709478 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ACT-709478|DRUG: Placebo|DRUG: Midazolam|DRUG: ACT-709478 combined with midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Administration of HS-10356 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: HS-10356|DRUG: Placebo|DRUG: HS-10356|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Endometrial Polypectomy Performed With Bipolar Electrode Versapoint and Laser Diode. A Randomised Controlled Trial.
Status: COMPLETED
Conditions: Endometrial Polyps
Interventions: PROCEDURE: polyps resection with Laser Diode|PROCEDURE: polyps resection with bipolar electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults MASLD Patients (DELI_MASLD Study)
Status: COMPLETED
Conditions: Metabolic Dysfunction Associated Steatotic Liver Disease|Steatotic Liver Disease|Hepatic Steatosis
Interventions: DIETARY_SUPPLEMENT: Probiotic lysate (postbiotic and metabiotc)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 Fatty Acid Supplementation on Inflammatory Response in Multisystem Trauma Patients
Status: TERMINATED
Conditions: Multiple Trauma
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mobilization With Movement Along With Sensory Motor Training in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Sensory Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: IL-15 Super Agonist ALT-803 to Treat Relapse Of Hematologic Malignancy After Allogeneic SCT
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Myelodysplastic Syndromes (MDS)|Lymphoma|Myeloma|Chronic Lymphocytic Leukemia (CLL)|Chronic Myelogenous Leukemia (CML)
Interventions: BIOLOGICAL: ALT-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mobile Application Dexteria Fine Motor Skills on Hand Dexterity and Grip Strength in Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke, Ischemic|Skill, Social|Occlusion
Interventions: OTHER: app based training with conventional therapy|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: AD-221|DRUG: AD-221A|DRUG: AD-221B|DRUG: AD-221C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in HCV Genotype 1 or 4 Patients Resistant to Bitherapy Alone
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: Interleukin-7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telmisartan and Amlodipine Versus Monocomponent Tablets
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan/Amlodipine Combination Tablet|DRUG: Amlodipine Monocomponent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Cognitive Processing Therapy (CPT) and Dialogical Exposure Therapy (DET) for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Dialogical exposure therapy|BEHAVIORAL: Cognitive Processing Therapy (German Adaptation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma Recurrent
Interventions: DRUG: DFMO|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hot Application on Post Laparoscopic Shoulder Pain and Analgesic Use
Status: COMPLETED
Conditions: Pain, Shoulder
Interventions: OTHER: hot application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccine Therapy in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Stage II Multiple Myeloma|Stage III Multiple Myeloma|Refractory Plasma Cell Neoplasm
Interventions: DRUG: autologous tumor cell vaccine|DRUG: keyhole limpet hemocyanin|DRUG: melphalan|DRUG: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: RCT of Ballon Technique VS Selective Ophthalmic Artery Infusion For the Retinoblastoma Patients
Status: UNKNOWN
Conditions: Retinoblastoma|IAC|Selective Ophthalmic Artery Infusion|Ballon Technique
Interventions: DEVICE: Ballon Technique|DEVICE: SOAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating JUVÉDERM® VOLUMA® XC Injectable Gel for Correction of Temple Hollowing in Adult Participants ≥ 22 Years Old
Status: COMPLETED
Conditions: Temple Hollowing
Interventions: DEVICE: JUVÉDERM® VOLUMA® XC|OTHER: No-treatment control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BIOLOGICAL: TILT-123|BIOLOGICAL: KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contegra Versus Pulmonary Homograft for Right Ventricular Outflow Tract Reconstruction in Newborns
Status: COMPLETED
Conditions: Congenital Heart Defect|Right Ventricular Outflow Tract Reconstruction
Interventions: PROCEDURE: right ventricular outflow tract reconstruction with contegra|PROCEDURE: right ventricular outflow tract reconstruction with pulmonary homograft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACAPHA in Preventing Lung Cancer in Former Smokers With Bronchial Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Lung Cancer|Precancerous Condition
Interventions: DIETARY_SUPPLEMENT: multi-herbal agent ACAPHA|DIETARY_SUPPLEMENT: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome
Status: COMPLETED
Conditions: Shoulder Hand Syndrome|Complex Regional Pain Syndromes
Interventions: DRUG: Suprascapular and median nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy, Safety and Tolerability of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide and Formoterol Fumarate in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium Bromide/Formoterol Fumarate|DRUG: Aclidinium Bromide/Formoterol Fumarate|DRUG: Aclidinium Bromide|DRUG: Formoterol Fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma|Limited Stage Lung Small Cell Carcinoma
Interventions: DRUG: Bomedemstat|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 3 Different Dosage Regimens of Hyaluronic Acid in Patients With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Hyaluronic acid 5 x 2.5 ml|DRUG: Hyaluronic acid 1 x 5 ml|DRUG: Hyaluronic acid 2 x 5 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Atorvastatin Reduce Ischemia-Reperfusion Injury in Humans in-Vivo?
Status: COMPLETED
Conditions: Ischemia Reperfusion Injury|Cardiovascular Disease
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Dexamethasone|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DIETARY_SUPPLEMENT: GlycosBio Nutritional Supplement + PERT placebo|DIETARY_SUPPLEMENT: Standard Nutritional Supplement + PERT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Functional Electrical Stimulation and Inspiratory Muscle Training in Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Combined training|OTHER: Electrical stimulation|OTHER: Inspiratory muscle training|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Radiofrequency Ablation in Pancreatic Neuroendocrine and Cystic Tumor
Status: COMPLETED
Conditions: Pancreatic Tumor|Endocrine Tumor|Neoplasms, Cystic, Mucinous, and Serous
Interventions: PROCEDURE: Radiofrequency Ablation under EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial With an Observational Component of Non-operative Versus Operative Treatment for AO Type A3 Fractures
Status: WITHDRAWN
Conditions: Spinal Fractures
Interventions: OTHER: Patient's Choice|PROCEDURE: Surgery + Bracing vs. Bracing Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of Monitor Maintenance Package Utilization
Status: NOT_YET_RECRUITING
Conditions: Alarm Fatigue|Patient Safety
Interventions: OTHER: Experimental group: CEASE Care Package and Remember Me Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Nourish Pilot & CoDesign Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: BEHAVIORAL: Nourish Intervention then No Intervention|BEHAVIORAL: No Intervention then Nourish Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study of the Therapy of Solar Lentigines With a Q-switched Rubin Laser Versus a Bleaching Cream
Status: COMPLETED
Conditions: Solar Lentigines
Interventions: DEVICE: Q-switched SINON Ruby Laser|DRUG: Pigmanorm Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Adult Pleomorphic Rhabdomyosarcoma|AJCC Grade 2 Sarcoma|AJCC Grade 3 Sarcoma|Alveolar Soft Part Sarcoma|Angiosarcoma|Clear Cell Sarcoma of Soft Tissue|Dedifferentiated Liposarcoma|Extraskeletal Ewing Sarcoma|Extraskeletal Myxoid Chondrosarcoma|Fibrosarcoma|Fibrosarcomatous Dermatofibrosarcoma Protuberans|Leiomyosarcoma|Malignant Peripheral Nerve Sheath Tumor|Myxofibrosarcoma|Pleomorphic Liposarcoma|Round Cell Sarcoma With EWSR1-non-ETS Fusion|Sarcoma|Soft Tissue Sarcoma|Soft Tissue Sarcoma of the Trunk and Extremities|Spindle Cell Sarcoma|Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Synovial Sarcoma|Undifferentiated Pleomorphic Sarcoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Chest Computed Tomography|PROCEDURE: Chest Radiography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Study to Evaluate a Probiotic in Mild to Moderate Psoriasis Patients
Status: COMPLETED
Conditions: Psoriasis
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PD-1 Inhibitor and Nab-paclitaxel and Bevacizumab in CUP
Status: UNKNOWN
Conditions: Cancer of Unknown Primary
Interventions: DRUG: Recombinant humanized anti-PD-1 monoclonal antibody injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Botulinum Toxin Type-A (Dysport®) in Continent Female Subjects Suffering From Idiopathic Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Confirm the Effectiveness of Predictix Genetics Antidepressant -Guided Treatment in Adults With MDD
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Predictix Genetics Antidepressant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First-in-Human Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of Janus Kinase-1 Inhibitor PF-04965842 in Healthy Western and Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04965842|DRUG: Placebo|DRUG: PF-04965842|DRUG: Placebo|DRUG: PF-04965842|DRUG: Placebo|DRUG: PF-04965842|DRUG: Placebo|DRUG: PF-04965842|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block
Status: COMPLETED
Conditions: Axillary Nerve Block
Interventions: DRUG: Chloroprocaine HCl 2%|DRUG: Ropivacaine 0.75%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
Status: COMPLETED
Conditions: Binge Eating|Eating Disorders in Adolescence|Overweight and Obesity
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating|OTHER: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: PEGPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of Azacitidine and Durvalumab in Advanced Solid Tumors
Status: COMPLETED
Conditions: Microsatellite Stable Colorectal Carcinoma|Platinum Resistant Epithelial Ovarian Cancer Type II|Estrogen Receptor Positive and HER2 Negative Breast Cancer
Interventions: DRUG: Azacitidine|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the "Treat-and-extend" Scheme in Patients With Retinal Vein Occlusion (RVO) With and Without LASER Treatment of Ischaemic Retinal Areas
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Ranibizumab|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid-lowering Effects of an Astaxanthin Supplement in Volunteers With Mild Dyslipidaemia
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Astaxanthin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: European Aortic Data Collection Project
Status: RECRUITING
Conditions: Complex Abdominal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm|Aortic Arch Aneurysm|Chronic Aortic Dissection
Interventions: PROCEDURE: Endovascular Aortic Treatments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Outcomes of CAD/CAM Single-Retainer Monolithic Zirconia Ceramic Resin-Bonded Fixed Dentures Bonded With Two Different Resin Cements
Status: UNKNOWN
Conditions: Denture, Partial, Fixed, Resin-Bonded|Tooth Loss / Rehabilitation|Resin Cements
Interventions: DEVICE: Panavia V5 resin cement|DEVICE: Panavia F2.0 resin cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to Matched Participants With Normal Kidney Function
Status: COMPLETED
Conditions: Congestive Heart Failure|Renal Impairment
Interventions: DRUG: Pecavaptan (BAY1753011)|DRUG: Pecavaptan (BAY1753011)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbetocin Versus Oral Tranexamic Acid Plus, Buccal Misoprostol on Blood Loss After Vaginal Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: carbetocin|DRUG: Tranexamic acid plus misoprostol|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy
Status: COMPLETED
Conditions: Subclinical Hypothyroidism|Hypothyroxinemia|Pregnancy
Interventions: DRUG: Levothyroxine|DRUG: Placebo for Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Study of MP-214 in Patients With Chronic Phase or Elderly Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MP-214|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Improve Diabetes Outcomes in Older African American Women With Multi-Caregiving Burden
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Multi-Caregiving Intervention|BEHAVIORAL: Diabetes Enhanced Usual Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of MK-3475 (Pembrolizumab) in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Treatment With Platinum-based and Cetuximab Therapy (MK-3475-055/KEYNOTE-055)
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracranial Stereotactic Radiosurgery in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Essential Hypotension and Allostasis Registry
Status: RECRUITING
Conditions: Blood Pressure|Depression|Panic Attack|Fibromyalgia|POTS|Inappropriate Sinus Tachycardia|Coronary Heart Disease|Acute Coronary Syndrome (ACS)|Acute Myocardial Infarction (AMI)|Cerebrovascular Disease (CVD)|Transient Ischemic Attack (TIA)|Atrial Fibrillation|Diabetes Mellitus|Cancer|Systolic Heart Failure|Diastolic Heart Failure|Chronic Fatigue Syndrome|Syncope|Vasovagal Syncope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer
Status: WITHDRAWN
Conditions: Esophageal Cancer|Biliary Tract Cancer|GastroEsophageal Cancer|Hepatobiliary Neoplasm
Interventions: DRUG: DKN-01|DRUG: Atezolizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphadenectomy in Early Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Lymphadenectomy
Interventions: PROCEDURE: Completion staging surgery including systematic pelvic and para-aortic lymphadenectomy|PROCEDURE: Comprehensive staging surgery with no Lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders
Status: UNKNOWN
Conditions: Progressive Familial Intrahepatic Cholestasis
Interventions: DEVICE: Gastostomy-biliary tube|DEVICE: External biliary diversion, internal biliary diversion and nasobiliary tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Quadrivalent HPV Vaccine to Prevent Relapses of Genital Warts After Initial Therapeutic Response
Status: UNKNOWN
Conditions: Genital Warts
Interventions: BIOLOGICAL: Vaccination with Gardasil|BIOLOGICAL: Injection of Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Secondary Progressive|Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Relapse Free
Interventions: DRUG: Masitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Simvastatin in LAM and TSC
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis|Tuberous Sclerosis Complex
Interventions: DRUG: Simvastatin|DRUG: Sirolimus Oral Product|DRUG: Everolimus Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Resin-Modified Glass Ionomer Varnish in Preventing White Spot Lesions in Fixed Appliance Orthodontia
Status: WITHDRAWN
Conditions: White Spot Lesion
Interventions: DRUG: Vanish XT Dental Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low-level Laser Therapy Versus High Frequency on Pressure Ulcers Treatment
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: DEVICE: Low-level laser therapy AlGaInP|DEVICE: High-frequency therapy with O3 formation|OTHER: Wound dressing with saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levofloxacin in the Treatment of Chronic Functional Constipation Associated With PIB(Peristaltic Contraction-Inhibiting Bacterium) Infection
Status: RECRUITING
Conditions: Constipation
Interventions: DRUG: Levoﬂoxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelodysplasia
Interventions: BIOLOGICAL: Unmanipulated UCB|BIOLOGICAL: SR-1 UCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
Status: UNKNOWN
Conditions: Pigmentation|Redness
Interventions: OTHER: cyclic merocyanine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voice Guard Processing Evaluation in a Cohort of Subjects Implanted With the Neuro Cochlear Implant System
Status: COMPLETED
Conditions: Cochlear Implantation
Interventions: DEVICE: XDP sound processing strategy - Period 0|DEVICE: XDP sound processing strategy - Period 1|DEVICE: VG sound processing strategy - Period 1|DEVICE: XDP sound processing strategy - Period 2|DEVICE: VG sound processing strategy - Period 2|DEVICE: XDP sound processing strategy - Period 3|DEVICE: VG sound processing strategy - Period 3|DEVICE: Voice Track
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lmp1 and Lmp2 Specific CTLs Following Cd45 Antibody for Relapsed Ebv-Positive Hodgkin's Or Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Hodgkins Lymphoma|Non-Hodgkin Lymphoma
Interventions: GENETIC: LMP1 SPECIFIC CYTOTOXIC T-LYMPHOCYTES|GENETIC: LMP2-SPECIFIC CYTOTOXIC T-LYMPHOCYTES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Effect of High-frequency Transcranial Magnetic Stimulation in the Management of Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: DEVICE: rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Delayed Loading for Implants Retaining Mandibular Complete Overdenture
Status: COMPLETED
Conditions: Bone Loss|Dental Implant
Interventions: OTHER: Immediate loading of the implants|OTHER: Delayed loading of the implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and Oxaliplatin in Treating Patients With Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: oxaliplatin|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: PET/CT|FAPI|Oral Cancer
Interventions: DRUG: 68Ga-DOTA-FAPI|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Observational Study on the Natural Course of Chronic Pancreatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pancreatitis|Genetic Mutation|Smoking, Tobacco|Drinking, Alcohol
Interventions: BEHAVIORAL: smoking and alcohol assumption|DIAGNOSTIC_TEST: genetic sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Misoprostol for Second Trimester Termination of Pregnancy
Status: COMPLETED
Conditions: Termination of Pregnancy Second Trimester
Interventions: DRUG: misoprostol|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-treatment Photographs on Oral Hygiene Maintenance in Orthodontic Patients
Status: COMPLETED
Conditions: Oral Hygiene|Photographs
Interventions: DEVICE: Showing Pre-treatment photographs of the patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Novel Diagnostic Kit for the Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth in Women Presenting With Signs and Symptoms of Preterm Labor
Status: RECRUITING
Conditions: Preterm Birth
Interventions: DEVICE: PartoSure|DEVICE: Fetal Fibronectine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of 3D Printed Polyether Ether Ketone (PEEK) and Milled PEEK Indirect Restorations Compared to Hybird Resin Composite Indirect Restorations Over One Year Period of Time ( A Randomized Clinical Trial )
Status: NOT_YET_RECRUITING
Conditions: Clinical Performance
Interventions: OTHER: 3D printed PEEK restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Diagnostic Performance Indicators in Upper GI Endoscopy:PROSPERO Study
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastric Cancer|Barrett Esophagus|Gastric Atrophy|Gastric Intestinal Metaplasia|Duodenal Adenoma|Esophageal Dysplasia|Duodenum Cancer|Gastric Polyp|Barretts Esophagus With Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Online Intervention to Address Barriers to IBD Medication Adherence
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease (IBD)
Interventions: BEHAVIORAL: CBT based online intervention to elicit and address perceptual and practical barriers to taking medication.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia|Diabetes Mellitus|Diabetes, Autoimmune
Interventions: DRUG: Cholecalciferol|DRUG: Omega 3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Ton-bridge Carotid Stent for Carotid Artery Stenosis
Status: NOT_YET_RECRUITING
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: Ton-bridge carotid stent|DEVICE: WALLSTENT carotid stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Immunotherapy for Childhood Egg Allergy
Status: COMPLETED
Conditions: Hypersensitivity|Immediate Hypersensitivity|Food Hypersensitivity
Interventions: DRUG: Egg oral immunotherapy|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Methylprednisolone|DRUG: Dexamethasone|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Study on Pentostatin, Cyclophosphamide and Rituximab in Indolent B-Cell Non-Hodgkin-Lymphoma (B-NHL)
Status: UNKNOWN
Conditions: Immunocytoma/Morbus Waldenström|B-Cell Non-Hodgkin's Lymphoma|B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide, Pentostatin, Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Eyelid Warming Device for the Management of Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction (MGD)
Interventions: DEVICE: MGDRx® EyeBag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 2 Doses of Menactra®, a Meningococcal Conjugate Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Meningococcal Meningitis|Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate|BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dapagliflozin on Renal Outcomes and Bone Mineral Disease in Non-diabetic Chronic Kidney Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Bone Diseases, Metabolic
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
Status: RECRUITING
Conditions: Back Pain Lower Back Chronic|Chronic Pain
Interventions: DRUG: Buprenorphine Buccal Film [Belbuca]|OTHER: Urine Drug Screening|DEVICE: actigraph|BEHAVIORAL: PROMIS 29|OTHER: sit to stand test|OTHER: numerical rating scale pain score|BEHAVIORAL: patient global impression of function|BEHAVIORAL: PROMIS - sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nusantara Diet (Low Calorie and Low Sodium) for Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome|Diabetes|Hyperlipidemias
Interventions: DIETARY_SUPPLEMENT: Diet Nusantara|BEHAVIORAL: Nutrition Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD)
Status: COMPLETED
Conditions: Horton's Disease|Infectious Disease|Neoplasia|Solid Tumor|Hemopathy
Interventions: OTHER: 1 blood sample|OTHER: 2 to 3 blood samples (at inclusion, at 3 months and at 6 months in cases of relapse)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p