pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: School Lunch Salad Bars and Fruit and Vegetable Consumption
Status: TERMINATED
Conditions: Children, Only|Behavior, Eating|School|Obesity|Food Selection|Food Habits|Diet Modification|Adolescent Behavior
Interventions: BEHAVIORAL: New salad bar|BEHAVIORAL: Marketing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase IIa Exploratory Clinical Trial, to Examine the Safety and Efficacy of tPCS on Paediatric ADHD Participants
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DEVICE: Braingear Brainbuds Pulsed Current stimulation device|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|B-Cell Chronic Lymphocytic Leukemia|Lymphoma, B-Cell
Interventions: BIOLOGICAL: Anti-CD19 and anti-CD20 bicistronic CAR T- cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Added Value of Diffusion Weighted MRI in Evaluation of Sacroiliitis in Newly Diagnosed Patients of Spondyloarthropathy.
Status: NOT_YET_RECRUITING
Conditions: Spondyloarthropathy and Sacroilitis
Interventions: DIAGNOSTIC_TEST: Magnetic resonance Imaging scanners of sacroiliac joints.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: • Comparison of Blood Culture Contamination Rates
Status: NOT_YET_RECRUITING
Conditions: Blood Culture Contamination
Interventions: PROCEDURE: disinfection of the surface that the blood culture is taken
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Compare the Effects of Telemedicine Approach With Usual Care in Hypertension Management in China
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: Usual care|DEVICE: Self-management|OTHER: PCTM intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stereotactic Body Radiotherapy for Liver Tumors
Status: COMPLETED
Conditions: Liver Metastases|Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma
Interventions: RADIATION: Stereotactic body radiosurgery|RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Durvalumab Alone Versus Durvalumab With Olaparib in Patients Ineligible for Cisplatin With Muscle-Invasive Urothelial Carcinoma of the Bladder Followed by Radical Cystectomy
Status: TERMINATED
Conditions: Bladder Cancer|Urothelial Carcinoma
Interventions: DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose vs Low Dose I 131 +/- rhTSH for Differentiated Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: recombinant thyroid-stimulating hormone|RADIATION: Radiodine ablation without rhTSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Filgrastim|DRUG: Cladribine|DRUG: Cyclosporine|DRUG: Cytarabine (Ara-C)|DRUG: Fludarabine Phosphate|DRUG: Idarubicin|DRUG: Methylprednisolone|PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selumetinib in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Adenosquamous Carcinoma|Endometrial Clear Cell Adenocarcinoma|Recurrent Uterine Corpus Carcinoma
Interventions: OTHER: Diagnostic Laboratory Biomarker Analysis|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D2 Resection and HIPEC (Hyperthermic Intraperitoneal Chemoperfusion) in Locally Advanced Gastric Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: HIPEC (Hyperthermic Intraperitoneal Chemoperfusion) with oxaliplatin|PROCEDURE: Curative gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Assessment at Birth Comparing Stethoscope Versus Tap-based Application
Status: WITHDRAWN
Conditions: Asphyxia Neonatorum|Birth Asphyxia
Interventions: DEVICE: Heart rate assessment using the Neonatal Resuscitation Program 6-sec assessment method|DEVICE: Heart rate assessment using Tap-based smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia
Status: COMPLETED
Conditions: Erythrocyte Transfusion|Beta-Thalassemia
Interventions: DRUG: Luspatercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
Status: COMPLETED
Conditions: Gastric Cancer|Helicobacter Pylori Infection|Bismuth
Interventions: DRUG: Bismuth potassium citrate containing quadruple therapy|DRUG: Colloidal pectin bismuth capsules containing quadruple therapy|DRUG: Colloidal pectin bismuth particles A quadruple therapy|DRUG: Colloidal pectin bismuth particles B quadruple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
Status: COMPLETED
Conditions: Obesity, Childhood|Overweight, Childhood
Interventions: BEHAVIORAL: Restricted Sleep|BEHAVIORAL: Adequate Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Atorvastatin Versus Probucol on Small Dense LDL
Status: COMPLETED
Conditions: Chronic Nephropathy
Interventions: DRUG: Effects of atorvastatin versus probucol on small dense LDL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting With Anxiety: Helping Anxious Parents Raise Confident Children
Status: UNKNOWN
Conditions: Child Anxiety|Parent Anxiety|Parental Wellbeing|Child Wellbeing
Interventions: BEHAVIORAL: Raising Confident Children Course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA)
Status: COMPLETED
Conditions: Prostate Cancer|Urinary Incontinence|Beta-Alanine|Pelvic Floor Muscle Training|Radical Prostatectomy
Interventions: DRUG: Beta-Alanine|DRUG: Placebo|PROCEDURE: Pelvic floor muscle training (PFMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide With or Without Vaccine Therapy for Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PROSTVAC (rilimogene galvacirepvec/rilimogene glafolivec) -F/TRICOM|BIOLOGICAL: PROSTVAC (rilimogene galvacirepvec/rilimogene glafolivec) -V/TRICOM|BIOLOGICAL: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nab-paclitaxel-Lenvatinib-Pembrolizumab as Second-line Treatment in Advanced NSCLC Patients
Status: NOT_YET_RECRUITING
Conditions: Advanced Non-squamous Non-small-cell Lung Cancer|Recurrent Non-Squamous Non-Small Cell Lung Cancer|Metastatic Non-squamous Non Small Cell Lung Cancer
Interventions: DRUG: pembrolizumab|DRUG: lenvatinib|DRUG: albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: African-American Social Support Effectiveness Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Maternal Perinatal Depression
Interventions: BEHAVIORAL: African-American Social Support Effectiveness Treatment-Partners alleviating Perinatal Depression (ASSET-PPD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adoptive Transfer of iNKT Cells Combined With TACE to Treat Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: iNKT cells|DRUG: Cyclophosphamide|DRUG: Human recombinated Interleukin-2|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetic Interaction Between Candesartan and Felodipine After Ingestion of a Specific Meal
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Candesartan (test)|DRUG: Felodipine (test)|DRUG: Candesartan Cilexetil|DRUG: Felodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults
Status: RECRUITING
Conditions: Cardiovascular Disease
Interventions: DRUG: control olive oil (COO)|DRUG: palmitoleate-rich oil (PLO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apatinib Mesylate Versus Standard Second-line TKI in the Treatment of Advanced GIST
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Apatinib Mesylate|DRUG: Sunitinib, Imatinib dosage, Dasatinib, Reveratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Liquid and Reconstituted Lyophilized Subcutaneous Formulations of Caplacizumab.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Caplacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diagnostic HIV Ag/Ab Combo Assay
Status: COMPLETED
Conditions: Human Immunodeficiency Viruses
Interventions: DEVICE: ARCHITECT HIV Ag/Ab Combo|DEVICE: ARCHITECT HIV Ag/Ab Combo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
Status: COMPLETED
Conditions: Clinically Severe Obesity|Metabolic Complications After Jejunoileal Bypass|Nutritional Complications After Jejunoileal Bypass|Obesity Recidivism|Inadequate Initial Weight Loss|Intestinal Malabsorptive Syndrome|Protein Malnutrition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Eutideron, Etoposide, and Bevacizumab in Patients With Brain Metastases From Breast Cancer.
Status: RECRUITING
Conditions: Mammary Neoplasms, Human
Interventions: DRUG: eutidrone etoposide bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is the Rehabilitation Robotic a Safe and Effective Choice for Stroke Patients?
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robotic|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: tretinoin microsphere 0.04% gel|DRUG: vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implementation of a 12-week Adapted Physical Activity (APA) Program in People Suffering From Chronic Insomnia.
Status: UNKNOWN
Conditions: Exercise|Health Behavior|Sleep
Interventions: BEHAVIORAL: physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Duodenal Feeds in Very Low Birth Weight Infants
Status: RECRUITING
Conditions: BPD - Bronchopulmonary Dysplasia|VLBW - Very Low Birth Weight Infant|Feeding Disorder Neonatal|Feeding; Difficult, Newborn|Premature Birth|Chronic Lung Disease of Prematurity
Interventions: OTHER: Mode of Delivery of Feeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Standard or Hypofractionated Radiotherapy Versus Accelerated Partial Breast Irradiation (APBI) for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Lumpectomy
Interventions: RADIATION: Whole Breast Irradiation + Boost or Hypofractionated irradiation|RADIATION: Accelerated partial breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Responsive Person-Centered Care for Psychosis
Status: COMPLETED
Conditions: Psychotic Disorders
Interventions: BEHAVIORAL: Person-centered planning (PCP)|BEHAVIORAL: Community integration (CI)|BEHAVIORAL: Illness management recovery (IMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systems Analysis and Improvement Approach to Optimize the Task-shared Mental Health Treatment Cascade (SAIA-MH)
Status: RECRUITING
Conditions: Mental Health Disorder
Interventions: BEHAVIORAL: Systems Analysis and Improvement Approach for Mental Health (SAIA-MH)|BEHAVIORAL: Attentional Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03177)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Desloratadine 5 mg|DRUG: fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Balance Training Following STARS on Postural Control
Status: COMPLETED
Conditions: Kinesiophobia|Ankle Sprains|Sensory Deficit|Ankle Instability|Functional Performance
Interventions: OTHER: Exercise|OTHER: STARS (Sensory-Targeted Ankle Rehabilitation Strategies)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Diacerein 1% Ointment for Subjects With Epidermolysis Bullosa Simplex (EBS)
Status: TERMINATED
Conditions: Epidermolysis Bullosa Simplex
Interventions: DRUG: diacerein 1% ointment|DRUG: A placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Patient Simulation in Nursing Students' Approach Toward Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Educational Problems|Anxiety and Fear|Nurse-Patient Relations
Interventions: BEHAVIORAL: Education Based on Standard Patient Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fluorine F18-EF5 and Fludeoxyglucose F18 Positron Emission Tomography in Assessing Hypoxia and Glycolysis in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: fludeoxyglucose F 18|RADIATION: Fluorine F 18 EF5|PROCEDURE: Positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of Respiration Rate Algorithms
Status: COMPLETED
Conditions: Respiratory Rate|Pulse Oximetry
Interventions: OTHER: Recording of 12 lead ECG|OTHER: Recording of lying and standing blood pressure|OTHER: Recording of chest wall movement|OTHER: Recording of heart rate variability|OTHER: Recording of ECG and Pulse oximeter waveform at rest|OTHER: Recording of ECG and Pulse oximeter waveform during exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improvement of Quality of Life (QoL) Using Preference-Oriented QoLMonitoring in Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Quality of Life
Interventions: BEHAVIORAL: patient- and physician-centered QoL monitoring|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 500mg and Rosuvastatin 10mg
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: HCP1201 500/10mg|DRUG: Metformin SR 500mg|DRUG: Rosuvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL-SLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy in Treating Patients With Metastatic Cancer
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cimetidine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Stress and Life Quality of Patients Participating in Clinical Trials Versus Patients Non Participating
Status: COMPLETED
Conditions: Metastatic Neoplasm|Recurrent Hematologic Cancer
Interventions: OTHER: questionnaires|OTHER: questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementing Digital Health in a Learning Health System
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension|Heart Failure|Atrial Fibrillation|Metabolic Syndrome|Genetic Disease
Interventions: DIAGNOSTIC_TEST: Digital Health Device Diagnostics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: MT10109L in the Treatment of Lateral Canthal Lines With or Without Concurrent Treatment of Glabellar Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines|Glabellar Lines
Interventions: DRUG: MT10109L|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASPIRES (Activating Cancer Survivors and Their Primary Care Providers to Increase Colorectal Cancer Screening) Study
Status: ENROLLING_BY_INVITATION
Conditions: Colorectal Cancer|Early Detection of Cancer
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Patient activation|BEHAVIORAL: Primary care provider activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sarcopenic Obesity on Sleep in Individuals With Obesity Hypoventilation Syndrome
Status: NOT_YET_RECRUITING
Conditions: Obesity Hypoventilation Syndrome (OHS)|Obesity|Hypoventilation|Respiration Disorders|Sleep Disorder; Breathing-Related|Sarcopenia|Sarcopenic Obesity
Interventions: OTHER: Assessment-OHS|OTHER: Assessment-Sarcopenic Obesity With OHS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine
Status: COMPLETED
Conditions: Anemia|Leukemia, T-Cell|Lymphocytosis|Neutropenia|Thrombocytopenia
Interventions: DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison Study of PET/CT or PET/MRI Imaging to Magnetic Resonance Imaging (MRI) Alone in Men With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: PET/MRI with Gallium-68 labeled PSMA-HBED-CC|DRUG: Multiple PET/MRI with Gallium-68 labeled PSMA-HBED-CC|DRUG: PET/CT with Gallium-68 labeled PSMA-HBED-CC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Prebiotic or Synbiotic on Inflammatory Response and Indicators of Nutritional Status in Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Synbiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of RAD001 and Erlotinib in Patients With Advanced Non Small Cell Lung Cancer Previously Treated Only With Chemotherapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: RAD001|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effects of ADH-1 Given Intravenously as a Single Agent
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: ADH -1 (Exherin™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Picoprep Split-dose Before Colonoscopy in Children
Status: UNKNOWN
Conditions: Sodium Picosulfate Overdose|Magnesium Sulfate Overdose|Children, Only|Bowel Disease
Interventions: DRUG: split dose vs standard dose of sodium pico sulfate plus magnesium sulfate in children for bowel cleansing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinic-based HIV Identification and Prevention Project Using Electronic Resources
Status: RECRUITING
Conditions: HIV Prevention|Primary Care|PrEP
Interventions: BEHAVIORAL: Patient Level|BEHAVIORAL: Multilevel|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety Study of Adalimumab in the Treatment of Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa (HS)
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: NEST-1 (NeoSync EEG Synchronized TMS)|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Effectiveness of Giving Combination of Standard Chemotherapy Drugs Versus Combination of Standard Chemotherapy and New Drug Ixabepilone When Given Before Surgical Removal of Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ixabepilone|DRUG: Paclitaxel|DRUG: Cyclophosphamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Physiology Peri-Transcatheter Left-sided Valvular Interventions
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Mitral Regurgitation|Coronary Artery Disease|Fractional Flow Reserve
Interventions: DIAGNOSTIC_TEST: Coronary Physiology assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Brain Specific Biomarkers in Hydrocephalus
Status: RECRUITING
Conditions: Hydrocephalus, Normal Pressure|Biochemical Lesions Head Region|Brain Damage
Interventions: DIAGNOSTIC_TEST: Lumbar puncture|DIAGNOSTIC_TEST: External lumbar drainage|PROCEDURE: Ventriculo-peritoneal shunt placement|PROCEDURE: Prechamber puncture|PROCEDURE: Blood sampling #1|PROCEDURE: Blood sampling #2|PROCEDURE: Blood sampling #3|PROCEDURE: Blood sampling #4 and #5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of A Group A, C Polysaccharide Meningococcal and Type b Haemophilus Influenzal Conjugate Vaccine
Status: COMPLETED
Conditions: Meningitis|Influenza
Interventions: BIOLOGICAL: A+C+hib Conjugate Vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: A+C Vaccine|BIOLOGICAL: Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer
Status: RECRUITING
Conditions: Colonic Neoplasms|Rectal Neoplasms
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Progressive stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Arthrofibrosis|Osteoarthritis, Knee
Interventions: DRUG: Hydrocortisone|DRUG: Dextrose 5% in water (D5W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Gepotidacin|DRUG: Nitrofurantoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ranibizumab or Aflibercept After Bevacizumab in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Diabetic Retinopathy
Interventions: DRUG: Ranibizumab 0.5 MG/0.05 ML Intraocular Solution [LUCENTIS]|DRUG: Aflibercept 40 MG/ML Intraocular Solution [EYLEA]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect Of Virtual Reality Glasses Used During Splint Application On Children's Pain And Anxiety Levels.
Status: COMPLETED
Conditions: Pain, Acute|Anxiety Acute|Fractures, Bone
Interventions: OTHER: The group using virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Choice of 3rd Generation Cephalosporins on the Emergence of Resistance in the Microbiota Intestinal.
Status: COMPLETED
Conditions: Emergence of Bacterial Resistance to Antibiotics
Interventions: DRUG: ceftriaxone|DRUG: Cefotaxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomically Guided Radiation Therapy in the Management of Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: RADIATION: Genomically Guided Radiation Therapy|RADIATION: Genomically Guided Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study Applying MRD Techniques for Participants With Previously Untreated Multiple Myeloma Treated With D-VRd Prior To and After High-dose Therapy Followed by ASCT - TAURUS
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors (EMERGE-201)
Status: COMPLETED
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Urothelial Cancer|Poorly Differentiated Neuroendocrine Carcinomas|Homologous Recombination Deficient-Positive Malignancies Agnostic
Interventions: DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Prednisone to Treat STA Study(SPTSS)
Status: COMPLETED
Conditions: Subacute Thyroiditis
Interventions: DRUG: Prednisone 1 week|DRUG: Prednisone 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Intervention for Elderly in Emergency Services
Status: COMPLETED
Conditions: Stroke|Ischemic Attack|Diabetes Mellitus|Hypertension|Fragility
Interventions: OTHER: Factors associated with the use of emergency departments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Serum Biomarkers in Diagnosis and Predicting Prognosis of Ovarian Cancers
Status: UNKNOWN
Conditions: Endometrial Neoplasms|Ovarian Neoplasms
Interventions: DIAGNOSTIC_TEST: TFF3, SFRP4, Romo1, NFKB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creating Meaning Following Cancer: An Intervention to Improve Existential and Global Quality of Life
Status: UNKNOWN
Conditions: Non-metastatic Cancer|Adjustment Disorder
Interventions: OTHER: Cognitive-existential intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M
Status: UNKNOWN
Conditions: EGFR-TKI Resistant Mutation|Nonsmall Cell Lung Cancer|AZD9291|Brain Metastases
Interventions: DRUG: AZD9291 80mg oral each day|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caring for Persons With Dementia and Their Caregivers in the Community
Status: UNKNOWN
Conditions: Dementia|Cognitive Impairment
Interventions: OTHER: Multidisciplinary collaborative model of community care management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI)
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: DRUG: Fish oil (eicosapentaenoic acid and docosahexanoic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of CES for Fibromyalgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: Alpha-stim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoid Leukemia
Interventions: BIOLOGICAL: huCART19
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Rapamycin- vs. Zotarolimus-Eluting Stents to Reduce Coronary Restenosis
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: Rapamycin + Probucol-eluting stent (ISAR stent)|DEVICE: polymer based Zotarolimus-eluting stent (Endeavor Resolute)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Sequence of Dilatation and Lithotripsy on the Treatment of Choledocholithiasis With ERCP
Status: UNKNOWN
Conditions: Choledocholithiasis|Cholangiopancreatography, Endoscopic Retrograde
Interventions: PROCEDURE: First lithotripsy and then EPBD|PROCEDURE: First EPBD and then lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Serology by Immunoenzymatic Test (EIA) in HIV-infected Children Treated Early With Antiretroviral in the ANRS-Pediacam Study: Pathophysiological Mechanisms
Status: RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Pharmacokinetics and Pharmacodynamics of a Single Acute Dose of a Hemp-derived Oral Product With a 1:1 Ratio of CBD:CBD-A
Status: COMPLETED
Conditions: Cannabis
Interventions: DRUG: CBD 1mg/Kg|DRUG: CBD 2mg/Kg|DRUG: CBD 4mg/Kg|DRUG: Placebo CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Datopotamab Deruxtecan|DRUG: Rilvegostomig|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Day +60 WT1 Assessment on Bone Marrow in Predicting Relapse and Mortality After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Assessment of the WT1 Expression Level on Bone Marrow Samples Collected at Day +60 After Allogeneic Stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: LY2835219|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Tamoxifen|DRUG: Exemestane|DRUG: Everolimus|DRUG: Trastuzumab|DRUG: LY3023414|DRUG: Fulvestrant|DRUG: Pertuzumab|DRUG: Loperamide|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Cognitive Control Via Transcranial Continuous Electrical Stimulation of Additional Motor Areas in Parkinson's Patients
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: transcranial electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Storytelling Intervention to Promote Cervical Cancer Screening Uptakes Among Malawian Women Living With Human Immunodeficiency Virus
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Storytelling narrative videos on tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Nivolumab in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) That Have Either Failed or Are Not Eligible for Autologous Stem Cell Transplant (CheckMate 139)
Status: COMPLETED
Conditions: Lymphoma. Non-Hodgkin
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure
Status: RECRUITING
Conditions: Congestive Heart Failure
Interventions: DRUG: AB-1002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Vaccines, Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 7-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple
Interventions: DIAGNOSTIC_TEST: CT scan|DRUG: Antibiotics|PROCEDURE: Surgical Resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Vincristine|DRUG: Methotrexate|DRUG: Ara-C|DRUG: Dexamethasone|DRUG: G-CSF|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver
Interventions: DRUG: OA-235i (4 mg)|DRUG: OA-235i (8 mg)|DRUG: OA-235i Dose 3|DRUG: OA-235i Escalating Dose 4|DRUG: OA-235i Escalating Dose 5|DRUG: OA-235i Multiple Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management in Osteoarthritis Using the Centrally Acting Analgesics Duloxetine and Pregabalin
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: DRUG: Pregabalin or Duloxetine or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion"
Status: COMPLETED
Conditions: Recurrent IDHwt Gliomas With FGFR3-TACC3 Fusion|Recurrent IDHwt Gliomas With FGFR1-TACC1 Fusion
Interventions: DRUG: AZD4547
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Meal Test Study of LY900014 in Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro|DRUG: Insulin Aspart|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure
Status: TERMINATED
Conditions: Chronic Heart Failure
Interventions: PROCEDURE: CRT-P implantation|PROCEDURE: CRT-D implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure
Status: NO_LONGER_AVAILABLE
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Allogeneic Pancreatic Islet Cells|DRUG: Sirolimus|BIOLOGICAL: Basiliximab|DRUG: Tacrolimus|DRUG: Antibacterial, Antifungal, and Antiviral Prophylaxis|DRUG: Trimethoprim/sulfamethoxazole|DRUG: Clotrimazole|DRUG: Valganciclovir|DRUG: Heparin|DRUG: Enoxaparin|DRUG: Pentoxifylline|DRUG: Aspirin
Study Type: EXPANDED_ACCESS
Clinical trial: Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Lower Limb Ischemia
Interventions: DEVICE: IN.PACT Amphirion|DEVICE: Standard PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Acute Allergic Conjunctivitis.
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Ketotifen/naphazoline|DRUG: Naphazoline|DRUG: Ketotifen|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03)
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: Neo-T|COMBINATION_PRODUCT: Toripalimab|COMBINATION_PRODUCT: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DRUG: Ascorbic acid|DRUG: N-acetyl cysteine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 24-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Participants With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: migalastat HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children
Status: UNKNOWN
Conditions: Appendicitis Acute|Pediatrics|Analgesia
Interventions: DRUG: Levobupivacaine Hydrochloride 2.5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis in Adolescents and Children
Status: TERMINATED
Conditions: Allergic Rhinitis Due to Dust Mite
Interventions: DRUG: Dpte and Dfar Allergen Extracts|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Long-term Safety and Efficacy of Alpelisib in Patients With PIK3CA-Related Overgrowth Spectrum (PROS) Who Previously Participated in Study CBYL719F12002 (EPIK-P1)
Status: ACTIVE_NOT_RECRUITING
Conditions: PIK3CA-related Overgrowth Spectrum (PROS)
Interventions: DRUG: Alpelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy
Status: TERMINATED
Conditions: Melanoma|Non-small Cell Lung Cancer|Squamous Cell Carcinoma of Head and Neck|Urothelial Carcinoma|Renal Cell Carcinoma|Small-cell Lung Cancer|Cutaneous Squamous Cell Carcinoma|Anal Squamous Cell Carcinoma|Merkel Cell Carcinoma
Interventions: BIOLOGICAL: GEN-011|DRUG: IL-2|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT