pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: B007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Tolerability Study of FluvalAB FL-K-004 Trivalent Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vaccination with FluvalAB FL-K-004 trivalent flu vaccine|BIOLOGICAL: Vaccination with FluvalAB trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line Platinum
Status: COMPLETED
Conditions: Muscle Wasting|Non-Small Cell Lung Cancer
Interventions: DRUG: GTx-024|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Subclinical Atherosclerosis (an Early Sign of Heart Disease) in Healthy Adult Immigrant Asian Indians
Status: WITHDRAWN
Conditions: Healthy
Interventions: PROCEDURE: Flow Mediated Doppler (FMD)|DRUG: Nitroglycerin 0.4 mg sublingual
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Skin Barrier Biophysical Properties and Clinical Appearance After Moisturizer in Dry Skin
Status: COMPLETED
Conditions: Xerosis|Xerosis Cutis|Dry Skin; Eczema
Interventions: OTHER: virgin coconut oil|OTHER: virgin jojoba oil|OTHER: virgin almond oil|OTHER: white petrolatum ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label RCT for Chronic Severe AR : Entresto vs. CCB/ARB
Status: RECRUITING
Conditions: Aortic Valve Insufficiency
Interventions: DRUG: Sacubitril-valsartan|DRUG: Amlodipine-losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELDA: Elderly Breast Cancer - Docetaxel in Adjuvant Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: intraperitoneal nebulisation of magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke|Transient Ischemic Attack
Interventions: DRUG: Ticagrelor 90mg|DRUG: Clopidogrel 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of IMP4297 as Maintenance Treatment Following First-line Chemotherapy in Patients With Advanced Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: IMP4927|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
Status: RECRUITING
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Paroxetine|DRUG: Citalopram|DRUG: Escitalopram|DRUG: Desvenlafaxine|DRUG: Venlafaxine|DRUG: Gabapentin|DRUG: Clonidine|DRUG: Pregabalin|DRUG: Oxybutynin|DRUG: Any other SSRI/SNRI not already specified|DRUG: Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Anesthesia Technique on Postoperative Evolution After Urogenital Surgical Interventions
Status: UNKNOWN
Conditions: Anesthesia; Reaction|Adverse Effect of Other General Anesthetics|Adverse Anesthesia Outcome|Acute Kidney Injury
Interventions: PROCEDURE: epidural catheter insertion|PROCEDURE: robot assisted laparoscopic urogenital surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dabrafenib and Trametinib in Treating Patients With Erdheim Chester Disease With BRAF V600 Mutations
Status: WITHDRAWN
Conditions: Erdheim-Chester Disease
Interventions: DRUG: Dabrafenib Mesylate|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Trametinib Dimethyl Sulfoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Patients With Acute Coronary Syndrome (ACS)
Status: COMPLETED
Conditions: Smoking|Acute Coronary Syndrome
Interventions: BEHAVIORAL: Technique of in-vivo exposure (cigarette) and mental image exposure (craving)|BEHAVIORAL: conventional follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Paracetamol Compared Dexketoprofen for Postoperative Analgesia After Septoplasty
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium-protein Co-ingestion and Gut Hormones
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: Milk Mineral Supplement|DIETARY_SUPPLEMENT: Whey Protein Hydrolysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Compare Different Strategies of Mean Arterial Pressure Management During Cardiopulmonary By-pass
Status: RECRUITING
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: OTHER: Management of mean arterial pressure during cardiopulmonary by-pass in cardiac surgery interventions. The MAP will be mantained in the range of values of each study arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Efficacy, and Safety Study of Recombinant Factor VIII Single Chain (rVIII-SingleChain) in Children With Severe Hemophilia A
Status: COMPLETED
Conditions: Congenital Hemophilia A
Interventions: BIOLOGICAL: rVIII-SingleChain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exoskeleton and Spinal Cord Stimulation for SCI
Status: RECRUITING
Conditions: Spinal Cord Injury|Ambulation Difficulty|Muscle Spasticity
Interventions: DEVICE: Exoskeleton-Assisted Walking|DEVICE: Transcutaneous Lumbosacral Stimulation (TLS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Therapy for Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease
Interventions: BEHAVIORAL: Primary Intervention for Combination Therapy - IBD Coping Strategies Program|BEHAVIORAL: Time and Attention Control - IBD Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer|Anesthesia|Renal Protection|Acute Kidney Injury|Multimodal Analgesia
Interventions: DRUG: Multimodal analgesia using dexmedetomidine-ketamine-lidocaine mixture|DEVICE: Minimal flow sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mesenchymal Stem Cells for Radiation-induced Xerostomia
Status: UNKNOWN
Conditions: Radiation Toxicity|Xerostomia Due to Radiotherapy|Dry Mouth|Hyposalivation|Mesenchymal Stem Cells|Mesenchymal Stromal Cells|Long Term Adverse Effects
Interventions: BIOLOGICAL: Autologous adipose-derived mesenchymal stem/stromal cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Substance Abuse
Interventions: BEHAVIORAL: CBT and exposure therapy for PTSD|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
Status: RECRUITING
Conditions: Superficial Basal Cell Carcinoma|Squamous Cell Carcinoma in Situ
Interventions: DRUG: Combination cream of 5-fluorouracil and calcipotriene|DRUG: 5-fluorouracil cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploring Two Treatments for Misophonia
Status: COMPLETED
Conditions: Misophonia
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders|BEHAVIORAL: Process-based Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab Plus Non-biological DMARD in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Non-biological DMARDs
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: placebo|DRUG: non-biological DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorescence Angiography: Planning and Monitoring of Perforator Flaps
Status: TERMINATED
Conditions: Reconstructive Surgery
Interventions: DEVICE: Fluorescence angiography (Fluobeam™ imaging system developed by Fluoptics company)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Induction Chemotherapy and Toripalimab Followed by Radiotherapy in Unresectable Laryngeal/Hypopharyngeal Carcinoma
Status: RECRUITING
Conditions: Laryngeal Cancer|Hypopharyngeal Cancer
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Chemotherapy in Combination With Erlotinib,or Sequential Erlotinib for Treatment in Patients With NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: docetaxel|DRUG: pemetrexed|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance Tele-Rehab in Parkinson's Disease Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Balance Tele-Rehabilitation Agility Boot Camp (ABC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACTivating Fat OXidation Through Capsinoids
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Capsinoids + Exercise|OTHER: Placebo + Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Dydrogesterone and Micronized Progesterone Treatments in the Treatment of Threatened Miscarriage.
Status: NOT_YET_RECRUITING
Conditions: Miscarriage Threatening
Interventions: DRUG: Duphastone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of Belatacept Using Active Pharmaceutical Ingredient Manufactured by Process E Relative to Process C
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: BIOLOGICAL: Process E Belatacept|BIOLOGICAL: Process C Belatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Levobupivacaine and Ropivacaine for Femoral Neural Block
Status: TERMINATED
Conditions: Pain|Arthroplasty, Replacement, Knee
Interventions: DRUG: Levobupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sulcular Bristle Tip Technique (SBTT) With an Electric Toothbrush
Status: TERMINATED
Conditions: Gum Bleed
Interventions: OTHER: Sulcular Bristle Tip Technique (SBTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vasopressin, Steroid, and Epinephrine Treatment in Patients With Out-of-hospital Cardiac Arrest
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DRUG: Control Group|DRUG: Experimental Group 1|DRUG: Experimental Group 2|DRUG: Experimental Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Interventions in Return to Work for Patients With Neck and Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain|Neck Pain
Interventions: BEHAVIORAL: Exercises and work related rehabilitation|BEHAVIORAL: Brief intervention|BEHAVIORAL: multidisciplinary exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Assess the Effect of Fampridine (BIIB041) on Walking Ability and Balance in Participants With Multiple Sclerosis.
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: BIIB041 (PR Fampridine)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Resectoscopes Effects to Optic Nerve Sheath Diameter
Status: COMPLETED
Conditions: Optic Nerve Sheath Diameter
Interventions: PROCEDURE: Effect of different resectoscope fluids on optic nerve diameter measured by ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Steroid Treatment for Idiopathic Granulomatous Mastitis (LSTIGM)
Status: UNKNOWN
Conditions: Granulomatous Mastitis
Interventions: DRUG: Compound Betamethasone Injection|DRUG: Hydrocortisone Butyrate 0.1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nicorandil on Cardiac Sympathetic Nerve for the Patients of Acute ST Segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: nicorandil|DRUG: Placebo（normal saline）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Open-Label Trial of Tarceva in Women With Metastatic, Hormone- and HER2-Negative Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of an Exercise for Trunk Stabilization Performed in Stable and Unstable Surfaces for Chronic Low Back Pain.
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Placebo|OTHER: Stable surface exercises|OTHER: Unstable surface exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Digital and Clinical Workflow Using Patient Specific Sticky Bone /Implant Housing PEEK Shell in Anterior Atrophic Maxilla: A Case Series
Status: RECRUITING
Conditions: Ridge Augmentation
Interventions: PROCEDURE: sticky bone housed in PEEK Shell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Fycompa in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Perampanel|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Loteprednol Etabonate in Adults Undergoing Bilateral Cataract Surgery
Status: COMPLETED
Conditions: Inflammation Following Ocular Surgery
Interventions: DRUG: Generic Loteprednol Etabonate|DRUG: Reference Listed Drug (RLD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Adjuvant Chemotherapy With FOLFOX in HCC Patients After Resection
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Adjuvant chemotherapy|PROCEDURE: Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy
Status: TERMINATED
Conditions: Cardiomyopathy, Hypertrophic Obstructive
Interventions: DRUG: CT-G20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia in Remission|Adult Acute Lymphoblastic Leukemia in Complete Remission|Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission|Chronic Myelomonocytic Leukemia in Remission|Graft Versus Host Disease|Hodgkin Lymphoma|Minimal Residual Disease|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma|Plasma Cell Myeloma|Severe Aplastic Anemia|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan Hydrochloride|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-standardized vs. Standardized Screening for Dysphagia
Status: RECRUITING
Conditions: Dysphagia
Interventions: OTHER: Mann Assessment of Swallowing Ability (MASA) (dysphagia screening tool)|OTHER: Non-standardized clinical swallow evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5FU|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermatoscopy Guided Resection for Skin Cancer
Status: RECRUITING
Conditions: Basal Cell Carcinoma|Cutaneous Squamous Cell Carcinoma|Surgical Margin
Interventions: DEVICE: Dermatoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: DVD Decision Aid|BEHAVIORAL: Internet Based Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Atezolizumab|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Periodontitis on Bone Mineral Density in Postmenopausal Women
Status: COMPLETED
Conditions: PERIODONTITIS|Osteopenia
Interventions: DIETARY_SUPPLEMENT: calcium (500mg) and vitamin D (250I.U.)|PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With Hypertension
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: DRUG: Fosinopril|DRUG: Benidipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Postoperative Pain|Regional Anesthesia Morbidity
Interventions: PROCEDURE: ESP block|PROCEDURE: CASP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery
Status: COMPLETED
Conditions: Brain Tumor
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Bosentan|OTHER: Placebo|DRUG: Bosentan|DRUG: Sildenafil Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Addictions: A Randomized Clinical Trial of a Web Application Based on SMART Recovery
Status: COMPLETED
Conditions: Alcoholism
Interventions: BEHAVIORAL: SMART Recovery face-to-face meetings|BEHAVIORAL: Overcoming Addictions web application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Phase 2 Study to Investigate the Preliminary Efficacy and Safety of INNO-206 in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: INNO-206
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque, Dental|Gingivitis
Interventions: DRUG: Test regimen|DRUG: Control regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MOF on Exercise Blood Pressure
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Monomeric and oligomeric flavanols|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Nigella Sativa for the Prophylaxis to Radiation Induced Dermatitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DRUG: Imtenan Oil|DRUG: Baraka Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digital Health Promotion in Iringa, Tanzania
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis|Cysticercosis|Tapeworm Pork
Interventions: OTHER: Digital health promotion intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Ovarian Cancer|Melanoma|Triple Negative Breast Cancer|Colorectal Cancer
Interventions: DRUG: NM1F Injection|DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medically Tailored Meals for Cardiovascular Health Equity
Status: NOT_YET_RECRUITING
Conditions: Diet, Healthy|HbA1c|Blood Pressure
Interventions: BEHAVIORAL: Medically Tailored Meals and Nutritional Counseling|BEHAVIORAL: Cardiovascular Health Promotion Educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Solifenacin and Tamsulosin
Status: COMPLETED
Conditions: LUTS|Benign Prostatic Hyperplasia|Overactive Bladder
Interventions: DRUG: Tamsulosin|DRUG: Solifenacin|DRUG: Tamsulosin and solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iceland Screens, Treats or Prevents Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Monoclonal Gammopathy of Undetermined Significance
Interventions: OTHER: Clinical follow-up 1|OTHER: Mental Health and Quality of Life questionnaire|OTHER: Standard follow-up or treatment.|OTHER: Clinical follow-up 2|OTHER: Clinical follow-up 3|OTHER: Clinical follow-up control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Topical Azithromycin on Tear Film Thickness in Patients With Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: DRUG: Azithromycin|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Oats on Post Prandial Glucose Response
Status: COMPLETED
Conditions: Normoglycemic|Normal Body Weight
Interventions: OTHER: Oatmeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART
Status: ENROLLING_BY_INVITATION
Conditions: HIV-1-infection|HIV Disease Progression|Inflammation|HIV
Interventions: PROCEDURE: Venipuncture|PROCEDURE: Targeted physical medical exam|PROCEDURE: Urine pregnancy test|PROCEDURE: Anoscopy|PROCEDURE: Esophagogastroduodenoscopy (EGD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-based Visual Training in Patients Implanted With Trifocal Diffractive Intraocular Lenses
Status: COMPLETED
Conditions: Visual Disturbances and Blindness|Visual Acuity Reduced Transiently
Interventions: PROCEDURE: Implantation of trifocal diffractive intraocular lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine or Dideoxyinosine in HIV Positive, Asymptomatic and Symptomatic Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interleukin-2, Polyethylene Glycolated|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Text Messaging Intervention to Reduce Perinatal Depression Risk
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Episode
Interventions: OTHER: Text Messaging Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Clinical Performance of the Protecta ICD and CRT-D
Status: COMPLETED
Conditions: Tachyarrhythmias|Heart Failure|Ventricular Dysfunction
Interventions: DEVICE: Protecta VR-ICD|DEVICE: Protecta DR-ICD or CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant
Interventions: DRUG: BXQ-350 - Part 1 Dose Escalation: Safety and Tolerance|DRUG: BXQ-350 - Part 2 BXQ-350 Tumor and Plasma Concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation Over the Left VLPFC on Cognitive Reappraisal
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Cathodal tDCS|DEVICE: Anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mesenchymal Stem Cells in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Infusion of adipose tissue-derived stem/stromal cells and oral Cholecalciferol supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misopristol Versus Pitocin for Second Trimester Abortion
Status: COMPLETED
Conditions: Abortion, Missed
Interventions: DRUG: mifepristone and misopristol|DRUG: mifepristone and oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate CCS1477 in Haematological Malignancies
Status: RECRUITING
Conditions: Haematological Malignancy|Acute Myeloid Leukemia|Non Hodgkin Lymphoma|Multiple Myeloma|Higher-risk Myelodysplastic Syndrome|Peripheral T Cell Lymphoma
Interventions: DRUG: CCS1477|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digitally Enhanced Smoking Cessation for High Risk Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking|Smoking Cessation|Lung Cancer Screening|Smoking, Tobacco|Smoking Behaviors
Interventions: OTHER: Escape|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Pazopanib Monotherapy After First Line Chemotherapy in Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Pazopanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids for High Triglycerides in HIV-infected Patients
Status: COMPLETED
Conditions: HIV Infections|AIDS|Dyslipidemia|Hypertriglyceridemia
Interventions: DRUG: Omega-3 fatty acid administration|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tucatinib Combined With Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study
Status: WITHDRAWN
Conditions: Metastatic Colon Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Rectal Adenocarcinoma|Stage IV Colon Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Trastuzumab|DRUG: Trifluridine and Tipiracil Hydrochloride|DRUG: Tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sars-COV-2 (COVID-19) Immunity in immunoCOmpromised Populations
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS CoV 2 Infection|COVID-19
Interventions: DIAGNOSTIC_TEST: Humoral immunity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Pharyngeal Metrics to Predict Dysphagia Outcomes
Status: RECRUITING
Conditions: Dysphagia|Swallowing Disorders
Interventions: OTHER: standard of care lingual strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutritional Support in Pressure Ulcer Patients
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: DIETARY_SUPPLEMENT: Enriched nutrition formula|DIETARY_SUPPLEMENT: Control formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: DRUG: tipifarnib|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR TID and Pelubiprofen SR (as a Pelubiprofen 90 mg) Tablet QD in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: pelubiprofen (30mg) tablet IR|DRUG: pelubiprofen SR (as a pelubiprofen 90 mg) tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
Status: COMPLETED
Conditions: Scar Prevention
Interventions: DRUG: EXC 001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypnotherapy in Treating Chronic Pain in Cancer Survivors
Status: COMPLETED
Conditions: Anxiety|Cancer Survivor|Chronic Pain|Depression|Sleep Disorder
Interventions: PROCEDURE: Hypnotherapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Systemic Effects of Epidural Methylprednisolone Injection on Glucose Tolerance in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: intra-articular infiltration|DRUG: epidural infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Supplementation of 2'-Fucosyllactose in Allogeneic Bone Marrow Transplant Recipients
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplant
Interventions: DRUG: 2'-fucosyllactose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Solution Temperature and Fluid Deficit During Hysteroscopy
Status: RECRUITING
Conditions: Surgery
Interventions: OTHER: 0.9% Saline warmed to 37 degrees Celsius|OTHER: 0.9% Saline warmed to 24 degrees Celsius
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Small Intestinal Bacterial Overgrowth Contribute to Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia|Small Intestinal Bacterial Overgrowth|Chronic Abdominal Discomfort
Interventions: DRUG: Rifaximin|PROCEDURE: Lactulose Breath Test|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevasizumab Versus Intravitreal Triamcinolone in Central Retinal Vein Occlusion (CRVO)
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: Bevasizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Concussion Trial: Symptom Management vs Alternative Randomized Treatment of Concussion Trial
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury|Headaches Posttraumatic|Neck Pain|Dizziness
Interventions: PROCEDURE: Symptom-specific Headache Treatment|OTHER: Symptom-specific Dizziness &/or Neck Pain Treatment|BEHAVIORAL: Multimodal Concussion Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus
Status: COMPLETED
Conditions: Status Asthmaticus
Interventions: DRUG: Ipratropium|DRUG: 0.9% Sodium Chloride|DRUG: Albuterol|DRUG: corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition
Status: TERMINATED
Conditions: Severe Acute Malnutrition|Moderate Acute Malnutrition
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treating Immuno-metabolic Depression With Anti-inflammatory Drugs
Status: RECRUITING
Conditions: Depressive Disorder, Major|Inflammation
Interventions: DRUG: Celecoxib 400mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast for Patients With Obstructive Sleep Apnea Syndrome
Status: TERMINATED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Montelukast 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Ozanimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Indirect Revascularization For Symptomatic Intracranial Arterial Stenosis
Status: COMPLETED
Conditions: Intracranial Arterial Stenosis|Intracranial Atherosclerosis|Ischemic Stroke|Cerebral Angiogenesis
Interventions: PROCEDURE: Encephaloduroarteriosynangiosis (EDAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MBSR Treatment of Cognitive Impairment Among Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: MBSR(BC) 6 Week Program|BEHAVIORAL: BCES 6 Week Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Clinical Trial to Evaluate the Efficacy of an Online Cognitive Rehabilitation Programme (COPERIA-COG) for Patients With Persistent COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19|Neuro-Degenerative Disease|Psychological|SARS CoV 2 Infection
Interventions: OTHER: Sessions of cognitive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Sexual Abstinence Period on the Production of Reactive Oxygen Species in Patients Who Planned to Take Part in Intrauterine Insemination
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: BEHAVIORAL: sexual abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study With GW597599 And GR205171: Potential New Drugs For The Treatment Of Primary Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: GR205171|DRUG: GW597599
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Simple Fall-Arrest Harness vs. Adjustable Harness
Status: SUSPENDED
Conditions: Fall Accident|Fall Injury|Balancing Interference
Interventions: OTHER: Balance training with Fall-Arrest harness|OTHER: Balance training with Adjustable harness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FTC/RPV/TDF on T-Cell Activation, CD4+ T-Cell Count, Inflammatory Biomarkers and Viral Reservoir
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Emtricitabine/rilpivirine/tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 (Sebelipase Alfa) in Adult Subjects With Lysosomal Acid Lipase Deficiency
Status: COMPLETED
Conditions: Cholesterol Ester Storage Disease (CESD)|Lysosomal Acid Lipase Deficiency|LAL-Deficiency
Interventions: DRUG: sebelipase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of 12-lipoxygenase in Platelet Reactivity and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Thrombosis|Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Primrose oil|DIETARY_SUPPLEMENT: Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE