pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Radiotherapy for Malignant Astrocytomas in the Elderly
Status: COMPLETED
Conditions: Primary Brain Tumor|Anaplastic Astrocytoma|Glioblastoma Multiforme
Interventions: DRUG: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change in Oxygen Consumption Following Inhalation Beta Agonists in Healthy Adults
Status: COMPLETED
Conditions: Oxygen Consumption
Interventions: DRUG: Albuterol|DRUG: Levalbuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indicated Prevention With Long-chain Polyunsaturated Omega-3 Fatty Acids in Patients With 22q11 Microdeletion Syndrome.
Status: UNKNOWN
Conditions: 22q11 Deletion Syndrome
Interventions: DIETARY_SUPPLEMENT: omega-3 PUFAs|OTHER: Standard care|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Food Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg|DRUG: Accuretic™ Tablets 20 mg/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Trial of Two Prone Breast Radiotherapy Techniques With Randomization to Concurrent Versus Weekly Boost
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Arm 1 Daily Boost of Radiation Therapy|RADIATION: Arm 2 Weekly Boost of Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of PiCSO in Anterior STEMI Patients
Status: WITHDRAWN
Conditions: STEMI - ST Elevation Myocardial Infarction|Anterior Wall Myocardial Infarction
Interventions: DEVICE: PiCSO Impulse System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Protein Intake on Weight Loss of Overweight/Obese Adults
Status: COMPLETED
Conditions: Obesity|Weight Loss|Protein
Interventions: OTHER: Dietary recommendations including protein enriched bars|OTHER: Dietary recommendations without protein enriched bars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of Entinostat in Adult Subjects With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Renal Impairment|Healthy Volunteer
Interventions: DRUG: Entinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Evaluating the Safety and Efficacy of JCARH125 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: JCARH125|BIOLOGICAL: JCARH125 + anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoid Leukemia|Myeloproliferative Disease|Myelodysplastic Syndrome|Chronic Myeloid Leukemia|Chronic Myelomonocytic Leukemia
Interventions: DRUG: ARM A Cyclophosphamide|DRUG: ARM B Calcineurin inhibitor and methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oxaliplatin, Irinotecan, and Capecitabine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: irinotecan hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Riocigaut on Cerebral Vasodilation and Headache Induction in Healthy Volunteers
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Dose Riociguat 2,5 or 5mg|DRUG: Riociguat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study in Healthy Men to Test How BI 1839100 is Taken up and Handled by the Body
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 1839100 (C-14) formulation 1|DRUG: BI 1839100|DRUG: BI 1839100 (C-14) formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Perihabilitation in Older Veterans Undergoing Surgery
Status: COMPLETED
Conditions: Malnutrition|Nutritional Risk|Abdominal Surgery
Interventions: DIETARY_SUPPLEMENT: Protein enhanced nutrition intervention|OTHER: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural Puncture Epidural
Status: UNKNOWN
Conditions: Labor Pain|Epidural|Pain, Labor
Interventions: PROCEDURE: Programmed intermittent bolus epidural|PROCEDURE: Provider administered analgesia on patient request
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the Combination of Diacerein 100 mg Daily and MTX Versus MTX Alone in the Treatment of Early Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Diacerein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes in India Nutrition Guidelines Study (DINGS)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: MNT according to AND EBNPG for Type 2 DM|OTHER: Usual Nutrition Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BG00012 Phase 2 Combination Study in Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Changes of the Short Portable Mental Status Questionnaire
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction
Interventions: DRUG: Ketamine|DRUG: physiological solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improvement in Scar Appearance Following Injection of Avotermin (Juvista) Into Skin Incisions Made in Healthy Men and Women
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Avotermin (Juvista)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-center Study on Surgical or Non-surgical Treatment for Children Type 1 Humeral Condyle Fracture
Status: UNKNOWN
Conditions: Treatment for Type I Humeral Condyle Fracture
Interventions: PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Combined With Anlotinib in Metastatic HER2 Negative Breast Cancer
Status: UNKNOWN
Conditions: HER2-negative Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy
Status: COMPLETED
Conditions: Posterolateral Thoracotomy|Postoperative Pain
Interventions: DRUG: EXPAREL 266 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurosensory Deficit of Inferior Alveolar Nerve Following Mandibular Orthognathic Surgery.
Status: COMPLETED
Conditions: Sensory Deficit
Interventions: PROCEDURE: Bilateral Sagittal Split Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dismantling the Components and Dosing of CBT for Co-Occurring Disorders
Status: COMPLETED
Conditions: CBT Decoupling|CBT Anxiety Reduction|CBT Combined
Interventions: BEHAVIORAL: De-coupling|BEHAVIORAL: Anxiety Reduction|BEHAVIORAL: Combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Sedentary Time on Skeletal Muscle Protein Metabolism
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: 7 days of habitual physical activity followed by 7 days of reduced physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbon Dioxide Versus Air Insufflation in Oesophago-gastro-duodenoscopy (OGD)
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: CO2 insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hemiablative Focal Brachytherapy Pilot Study
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Transperineal template guided mapping biopsy, multiparametric MRI, Hemiablative Focal Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfusion Magnetic Resonance Imaging in Diagnosing Patients With Kidney Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Renal Cell Cancer|Stage II Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: PROCEDURE: Arterial Spin Labeling Magnetic Resonance Imaging|PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|PROCEDURE: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging|PROCEDURE: Perfusion Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of the Effectiveness and Safety of a Disposable Intra-vaginal Device for Stress Urinary Incontinence (SUI)
Status: COMPLETED
Conditions: Stress Urinary Incontinence (SUI)
Interventions: DEVICE: disposable, single-use pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)
Status: RECRUITING
Conditions: Hydrocephalus, Communicating|Hydrocephalus
Interventions: DEVICE: eShunt™ Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group A Pharyngitis in Children: The GASPARD Study
Status: UNKNOWN
Conditions: Group A Streptococcal Pharyngitis
Interventions: DRUG: Amoxicillin or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant +/- Vandetanib in Advanced Aromatase Inhibitor Resistant Breast Cancer
Status: UNKNOWN
Conditions: Neoplasms
Interventions: DRUG: Fulvestrant|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Oil Associated for Managing Anxiety and Pain During Bone Marrow Biopsy Procedures
Status: RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-component Intervention on Improving Fruit and Vegetable Consumption in Teenagers and Their Mothers
Status: COMPLETED
Conditions: Nutrition
Interventions: BEHAVIORAL: behavioral|BEHAVIORAL: behavioral|BEHAVIORAL: primary eduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-coronary Versus Intramyocardial Application of Enriched CD133pos Autologous Bone Marrow Derived Stem Cells
Status: TERMINATED
Conditions: Heart Failure
Interventions: OTHER: autologous CD133pos stem cell application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Community Based Approach to Control Cardiovascular Risk Factors in India
Status: COMPLETED
Conditions: Hypertension|Diabetes|Smoking|Cardiovascular Diseases
Interventions: BEHAVIORAL: Community health worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Heat Donation Through the Head or Torso on Mild Hypothermic Rewarming
Status: COMPLETED
Conditions: Rewarming by Shivering Heat Production Only|Rewarming by External Heat to the Torso|Rewarming by External Heat to the Head
Interventions: DEVICE: Rewarming modality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetics and Safety/Tolerability of Lacosamide in 3 Dosages in Healthy Male Korean Subjects
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide|DRUG: Lacosamide|DRUG: Lacosamide|OTHER: Placebo|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Entecavir for Chronic Hepatitis B Patients With Persistently Normal ALT
Status: UNKNOWN
Conditions: Chronic Hepatitis
Interventions: DRUG: Entecavir|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NEC Screening Abdominal Radiograph vs Bowel Ultrasound in Preemies
Status: TERMINATED
Conditions: Enterocolitis, Necrotizing|Premature Infant
Interventions: DIAGNOSTIC_TEST: Bowel Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Endogenous Melatonin and 6-hydroxymelatonin as Biomarkers for CYP1A2
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Session 1 (day 1)|OTHER: Session 2 (day 3)|OTHER: Session 3 (day 15)|OTHER: Session 4 (day 30)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining SBRT and Immunotherapy in Early Stage NSCLC Patients Planned for Surgery
Status: UNKNOWN
Conditions: NSCLC, Stage I
Interventions: RADIATION: SABR|COMBINATION_PRODUCT: SABR + pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Post-traumatic Stress Disorder After ICU Discharge With the IPREA3 Program
Status: UNKNOWN
Conditions: Critical Illness
Interventions: OTHER: Administration of the IPREA3 questionnaire|OTHER: Immediate feedback through electronic reminder messages|OTHER: Targeted interventions in each ICU to reduce discomforts|OTHER: 6 months follow-up to assess the prevalence of PTSD symptoms|OTHER: 1 year follow-up to assess psychiatric morbidity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Intranasal Morphine for Pain After Bunion Surgery
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DRUG: Intranasal Morphine (MNS075) 3.75 mg|DRUG: Intravenous Morphine 7.5 mg|DRUG: Intranasal morphine (MNS075) 7.5 mg|DRUG: Intranasal morphine (MNS075) 15 mg|DRUG: Intranasal morphine (MNS075) 30 mg|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Usefulness of Antibiotics in Smokers Receiving Dental Implants
Status: COMPLETED
Conditions: Dental Implant Therapy
Interventions: PROCEDURE: Antibiotic group|PROCEDURE: Non-Antibiotic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Isometric Handgrip Exercise -MRI in Children and Adolescents
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Isometric Handgrip Exercise during magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Transcutaneous Posterior Tibial Nerve Stimulation in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Transcutaneous Posterior Tibial Nerve Stimulation + Duloxetine 30 MG|DRUG: Duloxetine 30 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
Status: RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm|Aortic Arch Aneurysm
Interventions: DEVICE: Zenith® t-Branch|DEVICE: Terumo Arch Branch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Phase II Trial on Prophylactic Perihepatic Lymphadenectomy in Patients With Colorectal Cancer With Liver Metastasis
Status: COMPLETED
Conditions: Colorectal Cancer With Liver Metastasis
Interventions: PROCEDURE: perihepatic lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Status: RECRUITING
Conditions: Acute Cholecystitis
Interventions: PROCEDURE: Endoscopic ultrasound-guided gallbladder drainage|DRUG: Antibiotics first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study for Incidence of Proximal Junctional Kyphosis Between Parathyroid Hormone and Denosumab Following Adult Spinal Deformity Surgery : A Prospective, Randomized Controlled Trial
Status: UNKNOWN
Conditions: Spine Deformity
Interventions: DRUG: Forsteo|DRUG: Denosumab Prefilled Syringe [Prolia]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dyadic e-Health System on Enhancing Healthy Lifestyles of Older Adults With Sarcopenia
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: BEHAVIORAL: e-Health System with nutritional advice|BEHAVIORAL: The Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
Status: NOT_YET_RECRUITING
Conditions: Opioid Use|Fractures, Bone|Trauma
Interventions: DRUG: Narcotic pain medication|DRUG: Nonnarcotic pain medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate PEMF Therapy on Experimentally Inducted Pain in Subjects With Painful Peripheral Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Peripheral Diabetic Neuropathy
Interventions: DEVICE: Provant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Oral Nutritional Supplement With β-hydroxy-β-methylbutyrate in Lean Body Mass Among Taiwan Elderly
Status: COMPLETED
Conditions: Frail Elderly Syndrome|Nutrition Disorders in Old Age|Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Ensure® Plus Advance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lactobacillus Reuteri Versus Placebo in the Treatment and Prevention of Infantile Colic
Status: UNKNOWN
Conditions: Infantile Colic
Interventions: OTHER: Lactobacillus reuteri DSM 17938|OTHER: Placebo|DIETARY_SUPPLEMENT: L.reuteri + Vit D|DIETARY_SUPPLEMENT: Vit D placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Comparison of Transurethral Resection by Mean of White Light and Narrow Band Imaging
Status: COMPLETED
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: PROCEDURE: Narrow band imaging transurethral resection|PROCEDURE: Standard transurethral resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Incidence of Expression of Tumor Antigens in Pathologically Proven Stage I, II and III Non-Small Cell Lung Cancer(NSCLC) in Asiatic Patients
Status: COMPLETED
Conditions: Pathologically Proven Stage I, II and III Non-Small Cell Lung Cancer (NSCLC)
Interventions: OTHER: Data acquisition and analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery Outcomes
Status: COMPLETED
Conditions: Glaucoma|Glaucoma Open-Angle Primary
Interventions: PROCEDURE: XEN45 Gel stent|PROCEDURE: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Two Triple-Drug Combinations in Patients Who Have Never Been Treated With Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing Hysterectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Atypical Endometrial Hyperplasia|Endometrial Carcinoma
Interventions: DRUG: Megestrol Acetate|BIOLOGICAL: Pterostilbene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integration of Musculoskeletal Physical Therapy Care in the Patient Centered Medical Home
Status: COMPLETED
Conditions: Musculoskeletal Pain Disorder
Interventions: PROCEDURE: Physical Therapist Evaluation|PROCEDURE: Primary Care Physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Modified Atraumatic Restorative Treatment Using CPP ACP
Status: NOT_YET_RECRUITING
Conditions: Caries
Interventions: DEVICE: MI varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Evaluating the Combination of Ribociclib+Capecitabine in Locally Advanced/Metastatic Breast Cancer HER2 Negative
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Combination of ribociclib + capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Influenza Vaccine Evaluation
Status: COMPLETED
Conditions: Immune Response
Interventions: BIOLOGICAL: High Dose Influenza vaccine|BIOLOGICAL: Adjuvanted Influenza vaccine|BIOLOGICAL: Standard Dose Influenza vaccine|BIOLOGICAL: Recombinant Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Effects of Inhibiting Platelet Function on Circulating Cancer Cells in Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Plavix|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab and Bevacizumab With or Without Gemcitabine to Treat Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: BIOLOGICAL: cetuximab|BIOLOGICAL: bevacizumab|DRUG: gemcitabine|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Naronapride vs. Placebo in Gastroparesis
Status: RECRUITING
Conditions: Gastroparesis
Interventions: DRUG: Naronapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cixutumumab (IMC-A12) in Islet Cell Cancer
Status: COMPLETED
Conditions: Carcinoma|Neuroendocrine Tumors
Interventions: BIOLOGICAL: Cixutumumab|DRUG: depot octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HRS8179 on Brain Swelling After Large Hemispheric Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Swelling, Large Hemispheric Infarction
Interventions: DRUG: HRS8179|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of REnal Denervation for Resistant Hypertension on Exercise Diastolic Function and Regression of Atherosclerosis and the Evaluation of NEW Methods Predicting A successfuL Renal Sympathetic Denervation (RENEWAL-EXERCISE, -REGRESS, and -PREDICT Trial From RENEWAL RDN Registry)
Status: TERMINATED
Conditions: Resistant Hypertension
Interventions: PROCEDURE: Renal denervation|DRUG: adenosine infusion treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise Program and Branched Chain Amino Acid Supplementation in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: RE and BCAA Supplementation|OTHER: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Indications and Clinical Efficacy of Pelvic Organ Prolapse Surgery
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: transvaginal synthetic mesh|DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Healing After Endoscopic Sinus Surgery
Status: NOT_YET_RECRUITING
Conditions: Nasal Polyps|Chronic Sinusitis
Interventions: COMBINATION_PRODUCT: Thymoquinone (0.5%) and Olive oil ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/1b Study of MEDI3726 in Adults Subjects With Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: BIOLOGICAL: MEDI3726 Post-Chemo|BIOLOGICAL: MEDI3726 Pre-Chemo|BIOLOGICAL: MEDI3726 & Enzalutamide Combo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Immunogenicity of SCTV01C in Healthy Population Aged ≥18 Years Previously Vaccinated With mRNA COVID-19 Vaccine.
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01C|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Ectopic Calcification in Fahr's Disease or Syndrome
Status: RECRUITING
Conditions: Fahr Disease|Fahr Syndrome|Primary Familial Brain Calcification
Interventions: DRUG: Etidronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prevalence of Functional Digestive Disorders During Primary Sjögren Gougerot Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome|Digestive System Abnormalities
Interventions: OTHER: Global symptom score (GSS) questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preliminary Safety of The TRUE Vascular Graft for Hemodialysis Access (TRUE HD I Study)
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: BIOLOGICAL: natural human collagen arteriovenous graft for hemodialysis access
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Local anesthesia at incision site|DRUG: Sham QL|DRUG: Sham Local|DRUG: QL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female|Early-stage Breast Cancer|Lymph Node Metastases|Axillary Metastases|Sentinel Lymph Node
Interventions: PROCEDURE: Targeted Axillary Dissection|DIAGNOSTIC_TEST: Ultrasound of the axilla
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Open Major Hepatectomy for HCC Hepatectomy for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Open or laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Compound Danshen Dropping Pills (CDDP) on the Post-myocardial Infarction Ventricular Remodeling
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: Compound Danshen Dropping Pills (CDDP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of a Geriatric Intervention Plan Associated to a Comprehensive Geriatric Assessment on Autonomy, Quality of Life and Survival of Patients Aged 70 Years Old and More Surgically Treated for a Resectable Cancer (Thoracic, Digestive or Urologic). Randomized Multicentric Study
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: comprehensive geriatric assessment (CGA)|OTHER: Geriatric intervention plan (GIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study(Lobeglitazone, Warfarin)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lobeglitazone|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG)
Status: UNKNOWN
Conditions: Recurrent Glioblastoma
Interventions: COMBINATION_PRODUCT: Combined stereotactic radiosurgery and enhanced immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marimastat Following Chemotherapy in Treating Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: marimastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Reduction Internal Versus Percutaneous Sacroiliac Screw Fixation in Unstable Posterior Ring Injury of Pelvic
Status: UNKNOWN
Conditions: Orthopedic Disorder
Interventions: PROCEDURE: closed reduction percutaneous fixation with open reduction internal fixation of the posterior pelvic ring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Angiography-derived FFR|PROCEDURE: IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luminor Registry: Registry of the Results of Angioplasty With Drug-eluting Balloon (Paclitaxel) in the Treatment of Infrainguinal Occlusive Lesions and Restenosis From Prior Endovascular Procedures in This Sector.
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Paclitaxel-eluting balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Phase I Clinical Trial of Booster Vaccination of Adenovirus Type-5 Vectored COVID-19 Vaccine
Status: COMPLETED
Conditions: Adenovirus Type-5 Vectored COVID-19 Vaccine
Interventions: BIOLOGICAL: Adenovirus Type-5 Vectored COVID-19 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nonabsorbable Versus Absorbable Sutures for Anterior Colporrhaphy
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Polyglactin 910 or polydioxanone|DEVICE: Polyester or polypropylene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance-guided Adaptive Stereotactic Body Radiotherapy for Hepatic Metastases
Status: RECRUITING
Conditions: Hepatic Metastasis
Interventions: RADIATION: ITV (Internal target volume)-based Stereotactic Body Radiotherapy (ITV-SBRT)|RADIATION: MRgSBRT (Magnetic Resonance-guided Stereotactic Body Radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Asthma Exacerbations and Vascular Function
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mannitol|DRUG: Methacholine|DRUG: Placebo|OTHER: Rest|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraoperative Celiac Plexus Neurolysis for Patients With Operable Pancreatic and Periampullary Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Alcohol Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: levodopa-carbidopa|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Docetaxel and CMF in the Adjuvant Treatment of Elderly Women With High-Risk Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Zevalin Following R-CVP in Previously Untreated Patients With Follicular Non Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Follicular Lymphoma|Lymphoma, Follicular
Interventions: DRUG: Zevalin Therapeutic Regimen|DRUG: R-CVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)
Status: COMPLETED
Conditions: Surgical View|Shoulder Tip Pain|Abdominal Pain
Interventions: PROCEDURE: Pneumoperitoneum Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-intensity Interval Training in Heart Failure Patients With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Normal Ejection Fraction
Interventions: OTHER: High-intensity interval training (HIT)|OTHER: Moderate-intensity contiuous training (MCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coeliac Plexus Neurolysis Versus Splanchnic Nerve Neurolysis
Status: RECRUITING
Conditions: Cancer Pain
Interventions: OTHER: Coeliac plexus neurolysis|OTHER: Splanchnic nerve neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Bupropion Sustained Release 150 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bupropion 150 mg Extended-Released Tablet, single dose|DRUG: Wellbutrin SR® 150 mg Sustained-Release Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Fermented Oyster Extract on Musculoskeletal Biomarkers in Relative Sarcopenia Adults
Status: COMPLETED
Conditions: Muscular Sarcoidosis
Interventions: DIETARY_SUPPLEMENT: Fermented oyster extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Myomectomy Using Barbed or Conventional Sutures
Status: COMPLETED
Conditions: Fibroid
Interventions: PROCEDURE: myomectomy using barbed sutures|PROCEDURE: myomectomy using conventional sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological and Neuropsychological Sequelae of COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Neuropsychological assessment|DIAGNOSTIC_TEST: Questionnaires Patient|DIAGNOSTIC_TEST: Questionnaires Family
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate Efficacy of Reinduction With Nadofaragene Firadenovec in Subjects With CIS ± High-grade Ta/T1 and no Complete Response to First Nadofaragene Firadenovec Dose.
Status: RECRUITING
Conditions: Bladder Cancer|Ta/T1|CIS
Interventions: DRUG: nadofaragene firadenovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Should Surgical Residents Be Educated About Patient Safety
Status: COMPLETED
Conditions: Medical Education|Patient Safety|Educational Safety Curriculum|Surgical Resident
Interventions: BEHAVIORAL: Education - BIPS course|BEHAVIORAL: Formal safety curriculum|BEHAVIORAL: Ongoing evaluation and feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: SCD Shared Decision-Making Toolkit for AYAs - including VR|BEHAVIORAL: SCD Shared Decision-Making Toolkit for AYAs - without VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiofrequency Ablation vs Conventional Surgery for Superficial Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: PROCEDURE: Conventional Surgery|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Pre-sacral Nerve Block on Post-operative Pain Following Laparoscopic Hysterectomy
Status: RECRUITING
Conditions: Gynecology
Interventions: PROCEDURE: pre-sacral nerve block (bupivacaine injection into both uterosacral ligaments at the end of laparoscopic hysterectomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Rapydan Topical Anaesthesia for Arterial Cannulation
Status: COMPLETED
Conditions: Arterial Catheterization
Interventions: DRUG: Lidocaine/tetracaine patch|DRUG: Placebo Patch|DRUG: Subcutaneous injection of 0.5 ml Lidocain 1%|DRUG: Subcutaneous injection of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Prostatitis|Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: DRUG: CC-10004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Stress Hyperglycemia|Cortisol; Hypersecretion|Inflammatory Response|Coagulation
Interventions: DIAGNOSTIC_TEST: Serum cortisol.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic Kidney Disease (CKD) Platelet Study
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Heart Attack|Stroke, Ischemic
Interventions: DRUG: Ticagrelor 90mg|DRUG: Clopidogrel 75mg|DRUG: Aspirin 81 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant ,Olanzapine,Palonosetron and Dexamethasone for the Prevention of Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Olanzapine|DRUG: Aprepitant|DRUG: Palonosetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION