pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: Cisplatin|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocan Level in Patients With Erectile Dysfunction and Relationship With Tadalafil Treatment
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DIAGNOSTIC_TEST: Endocan|DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety in Patients With Type 2 Diabetes Mellitus and Cardiovascular Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease|Inadequate Glycaemic Control
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biochemical Evaluation of Dental and Periodontal Conditions in Children With Juvenile Idiopathic Arthritis
Status: UNKNOWN
Conditions: Juvenile Idiopathic Arthritis|Gingivitis|Decay, Dental
Interventions: DIAGNOSTIC_TEST: Humans ELISA kits
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A
Status: COMPLETED
Conditions: Severe Hemophilia A
Interventions: DRUG: rFVIIIFc|DRUG: rFVIIIFc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ropivacaine 0,2% Plus Dexamethasone Versus Ropivacaine 0,2% Plus Placebo in Modified Pectoral Block
Status: UNKNOWN
Conditions: Effect of Drugs|Breast Pain|Anesthesia, Local
Interventions: DRUG: Dexamethasone|DRUG: Placebo|DRUG: Ropivacaine Injection [Naropin]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Adjuvanted Prophylactic Hepatitis B Vaccine
Status: COMPLETED
Conditions: Exposure to Hepatitis B Virus
Interventions: DRUG: HBsAg|BIOLOGICAL: PreS HBsAg|BIOLOGICAL: Advax-1(TM)|BIOLOGICAL: Advax-2(TM)|BIOLOGICAL: Advax-3(TM)|BIOLOGICAL: Alum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY900014 and Insulin Lispro With an External Continuous Subcutaneous Insulin Infusion System in Adult Participants With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Type 1
Interventions: DRUG: LY900014|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DHA Proof-of-Concept Study in Infants and Toddlers
Status: WITHDRAWN
Conditions: Infants|Toddlers|Nutritional Supplement
Interventions: OTHER: blend of glycerides at certain proportions|OTHER: glycerides used in current formulas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion (CAPITAL-RAPTOR)
Status: RECRUITING
Conditions: Radial Artery Occlusion
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Supplement for Patients With Tibial Fracture
Status: UNKNOWN
Conditions: Tibial Fracture
Interventions: DRUG: Placebo orally everyday|DRUG: Vitamin D3 cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Social Intelligence Training for Custodial Grandfamilies
Status: UNKNOWN
Conditions: Emotional Intelligence|Quality of Life|Social Competence
Interventions: BEHAVIORAL: Online Social Intelligence Training|BEHAVIORAL: Attention Control (AC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: DRUG: ezetimibe (+) simvastatin|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: D-1553 Tablet|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of A Novel Approach to Titrate Basal Insulin (LY2963016) in Participants With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes|Type 2 Diabetes Treated With Insulin
Interventions: DRUG: Basal Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Yervoy in Combination With Adoptive T Cell Transfer for Metastatic Melanoma Patients
Status: TERMINATED
Conditions: A Combination of Adoptive T Cell Therapy and Ipilimumab Could Increase the Proportion of CR Patients, and Durability of Response
Interventions: BIOLOGICAL: Adoptive cell transfer|DRUG: Ipilimumab 5 MG/ML Injection [Yervoy]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Therapy as a Method Supporting the Cardiac Rehabilitation
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Depressive Symptoms|Mood Disorders|Anxiety State|Stress
Interventions: BEHAVIORAL: Cardiac rehabilitation|DEVICE: Virtual therapeutic support|BEHAVIORAL: Standard therapeutic support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of FloSeal in Hemostasis After Laparoscopic Ovarian Cystectomy
Status: COMPLETED
Conditions: Benign Ovarian Tumor
Interventions: PROCEDURE: FloSeal application|PROCEDURE: Electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Glucose Tolerance in Subjects at Risk for Diabetes With Low Vitamin D.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Acute Intermitted Hypoxia|PROCEDURE: Massed Practise|OTHER: Rapael Glove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multisensory Telerehabilitation for Visual Field Defects
Status: COMPLETED
Conditions: Visual Field Defect Following Cerebrovascular Accident|Hemianopia|Brain Injuries
Interventions: BEHAVIORAL: Audio-visual training (AVT) telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Flexible-dose Vardenafil in Subjects With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 in Type 2 Diabetes Mellitus When Failing on OADs
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Semaglutide weekly injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perfusion Assessment in Laparoscopic Left Anterior Resection
Status: COMPLETED
Conditions: Rectal Cancer|Colon Cancer|Crohn's Disease|Polyp|Procidentia|Diverticulitis
Interventions: DEVICE: PINPOINT Endoscopic Fluorescence Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Uric Acid Effects on Endothelium and Oxydative Stress
Status: COMPLETED
Conditions: Oxidative Stress|Endothelial Function|Cardiovascular System|Hypertension
Interventions: DRUG: Placebos|DRUG: Febuxostat|DRUG: Rasburicase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Transfers of Fresh and Thawed Embryos in Patients With Prior Failed Embryo Transfer Cycles
Status: WITHDRAWN
Conditions: Infertility|Subfertility
Interventions: PROCEDURE: Embryo cryopreservation|PROCEDURE: Fresh embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Kinesio Tapping on Quadriceps Muscle Peak Torque and Bioelectrical Activity After Meniscectomy
Status: COMPLETED
Conditions: Meniscus Tear
Interventions: OTHER: Cura Kinesio-taping|OTHER: Placebo kinesio-taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 5x-Multiplier vs 3-Tier Model for Discharge Opioid Prescriptions After Intra-abdominal Cancer Surgery: A Randomized Clinical Trial
Status: RECRUITING
Conditions: Intra-abdominal Cancer
Interventions: DRUG: Hydrocodone|DRUG: Tramadol|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving
Status: COMPLETED
Conditions: Distracted Driving|Impaired Driving|Driving Behaviors
Interventions: BEHAVIORAL: Persuasive education|BEHAVIORAL: WOOP (aka, mental contrasting with implementation intentions., Wish, Outcome, Obstacle, Plan)|BEHAVIORAL: Customized Habit Tips|BEHAVIORAL: Raffle Financial Incentive|BEHAVIORAL: Shared Pot Financial Incentive|BEHAVIORAL: Weekly SMS Support text|BEHAVIORAL: Weekly SMS Encouragement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Armolipid on Lipid Profile in Children With Hypercholesterolemia
Status: COMPLETED
Conditions: Dyslipidemias|Children, Only
Interventions: DIETARY_SUPPLEMENT: Effect of Armolipid on Lipid Profile in Children With Hypercholesterolemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Vertebroplasty for Painful Acute Osteoporotic Vertebral Fractures
Status: COMPLETED
Conditions: Osteoporosis|Vertebral Fracture
Interventions: PROCEDURE: percutaneous vertebroplasty|PROCEDURE: sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Head Circumference Growth in Children With Ehlers-Danlos Syndrome Who Develop Dysautonomia Later in Life
Status: COMPLETED
Conditions: Ehlers Danlos Syndrome|External Hydrocephalus|Dysautonomia|Postural Orthostatic Tachycardia Syndrome|Venous Insufficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Autoimmune Diseases
Status: COMPLETED
Conditions: Fasting|Chronic Disease|Autoimmune Diseases|Metabolic Disease|High Blood Pressure|Fatty Liver|Kidney Stone|Gall Stone|Hysteromyoma
Interventions: OTHER: the 21-day fasting-like diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development and Acceptability Testing of Ready-to-use-complementary Food Supplement (RUCFS) for Children in Bangladesh
Status: COMPLETED
Conditions: Moderately Malnourished Children
Interventions: DIETARY_SUPPLEMENT: Pushti packet|DIETARY_SUPPLEMENT: Rice based Ready to Use Complementary Food Supplements|DIETARY_SUPPLEMENT: Chick-pea based Ready to Use Complementary Food Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Validation of Aer-O-Scope Colonoscope System Cecal Intubation
Status: COMPLETED
Conditions: Colonic Polyp|Colonic Neoplasms|Colonic Diseases|Colon Adenoma|Colon Disease|Colon Adenocarcinoma|Colon Cancer
Interventions: DEVICE: Aer-O-Scope Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: New Biomarkers for Invasive Fungal Infections in Paediatric Haemato-oncology
Status: TERMINATED
Conditions: Haemato-oncological Paediatric Patients Under Intensive Chemotherapy
Interventions: OTHER: Non Standard of Care blood samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improved Operation of Low Intraocular Pressure in Phacoemulsification for Patients With High Myopia Complicated With Cataract
Status: UNKNOWN
Conditions: High Myopia|Low Intraocular Pressure
Interventions: PROCEDURE: Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK0249 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0249-016)
Status: COMPLETED
Conditions: Paranoid Schizophrenia
Interventions: DRUG: MK0249|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Laryngeal Mask Airway in Edentulous Geriatric Patients
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DEVICE: Group LMA Unique™|DEVICE: Group LMA Supreme™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: DRUG: Pitavastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Safety and Efficacy of MD05 in Comparison With Beta-TCP in Patients Undergoing Sinus Floor Augmentation
Status: UNKNOWN
Conditions: Alveolar Ridge Augmentation
Interventions: DRUG: MD05|DEVICE: Beta-TCP and autologous bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics of Golimumab in Japanese and Caucasian Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: 400 mg golimumab or placebo|DRUG: 200 mg golimumab or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Clear Cell Renal Cell Carcinoma|Hepatocellular Carcinoma|Non-small Cell Lung Cancer
Interventions: DRUG: CHS-388|DRUG: Pembrolizumab|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifampin 300 Mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration Physiotherapy in Kidney Transplantation
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: OTHER: Stochastic whole body vibration (WBV) therapy - Physiotherapeutical intervention|OTHER: Stochastic whole body vibration (WBV) therapy - Sham physiotherapeutical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radioactive Iodide (131I) Treatment of 124I PET/CT Detected Breast Cancers
Status: WITHDRAWN
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: PROCEDURE: 124 PET/CT imaging|DRUG: Na134I|DRUG: Tri-iodothyronine|DRUG: Tri-iodothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Muscle Invasive Bladder Urothelial Carcinoma|Bladder Cancer TNM Staging|Bladder Cancer Stage IIa|Bladder Cancer Stage IIb|Bladder Cancer Stage IV|Bladder Leiomyosarcoma|Bladder Cancer|Bladder Cancer Stage II|Bladder Cancer Stage IIIa|Bladder Cancer Stage IIIb|Bladder Cancer Stage IIIc|Bladder Urothelial Carcinoma|Progression, Disease|Urinary Diversion|Neobladder|Radical Cystectomy
Interventions: PROCEDURE: Radical Cystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A RANDOMIZED CONTROLED TRAIL COMARING LARYNGEAL TUBE SUCTION DISPOSABLE AND I-gel IN PEDIATRIC PATIENT
Status: UNKNOWN
Conditions: Seal Pressure
Interventions: DEVICE: LTSD|DEVICE: i-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer Metastatic|Gastric Cancer|Esophageal Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma|Colorectal Cancer
Interventions: DRUG: MCLA-129|DRUG: Osimertinib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SORAVE - Sorafenib and Everolimus in Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Non-Small Cell Lung Cancer
Interventions: DRUG: Combination of sorafenib and everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm Without Rupture
Interventions: DEVICE: Nellix® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Children With Visual Pathway Glioma
Status: COMPLETED
Conditions: Visual Pathway Glioma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lunatocapitate Fusion Versus Four-corner Fusion for SNAC and SLAC Arthritis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Wrist Arthritis
Interventions: PROCEDURE: Lunate-Capitate Fusion (LCF)|PROCEDURE: Four Corner Fusion (4CF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nursing Interventions Based on Conservation Motivation Theory on Drug Adherence and Healthy Lifestyle Behaviors in Patients With Hypertension: A Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Hypertension, Public Health; Nursing Staff
Interventions: BEHAVIORAL: Nursing interventions based on protection motivation theory in patients with hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation
Status: COMPLETED
Conditions: Occupational Stress
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Daily Examen spiritual practice|BEHAVIORAL: Stress inoculation combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
Status: RECRUITING
Conditions: Colorectal Cancer|Pancreatic Ductal Cancer|Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
Interventions: DRUG: BGB-3245|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Telmisartan Compared With Losartan
Status: RECRUITING
Conditions: Diabetic Nephropathies|Hypertension
Interventions: DRUG: telmisartan|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercises and Postural Stabilization Exercises in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome|Physiotherapy|Rehabilitation
Interventions: OTHER: aerobic exercise|OTHER: postural stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute and Chronic Effects of Dynamic Apnea in Healthy Untrained Subjects
Status: COMPLETED
Conditions: Apnea
Interventions: OTHER: Program of training with exercises including apnea|OTHER: Program of training with exercises without apnea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Hepatitis in Patients Who Are Triple-Infected With HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV)
Status: WITHDRAWN
Conditions: HIV Infections|Hepatitis B|Hepatitis C
Interventions: DRUG: Adefovir dipivoxil|DRUG: Peginterferon-alfa-2A|DRUG: Ribavirin|PROCEDURE: Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Administration of L-Carnitine on Body Weight in Women in Crossfit Training
Status: UNKNOWN
Conditions: Body Weight Changes
Interventions: DRUG: L-Carnitine|DIETARY_SUPPLEMENT: Sucralose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study on the Evaluation of Acupuncture Therapy on Primary Insomnia
Status: RECRUITING
Conditions: Primary Insomnia
Interventions: OTHER: the acupuncture group|OTHER: the placebo acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabis Consumption and Driving Impairment Assessment on a Closed Course
Status: RECRUITING
Conditions: Cannabis Smoking|Driving Impaired
Interventions: DRUG: Active smoked cannabis|DRUG: Placebo smoked cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Maintenance Tegafur-uracil Versus Observation Following Adjuvant Oxaliplatin-based Regimen in Patients With Stage III Colon Cancer After Radical Resection
Status: UNKNOWN
Conditions: Stage III Colon Cancer
Interventions: DRUG: tegafur-uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Assess the Drug-drug Interaction of Acid Reducing Agent(s) on the Pharmacokinetics of a Single Oral Dose of Lumicitabine (JNJ-64041575) in Healthy Adult Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Lumicitabine|DRUG: Lansoprazole|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multicenter, Placebo-controlled, Double-blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Aripiprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)
Status: COMPLETED
Conditions: Hypertriglyceridemia|Familial Chylomicronemia
Interventions: DRUG: ARO-APOC3|DRUG: sterile normal saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Participants
Interventions: DRUG: PF-06651600 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma Bone Disease
Interventions: DRUG: BHQ880|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropsychologic and Immunological Evaluation in Treatment of Thyroid Diseases. Is Selenium Efficient?
Status: COMPLETED
Conditions: QoL Before and After 9 Month of Medical Treatment of Graves´Thyrotoxicosis|Potential Effect of Selenium
Interventions: OTHER: selenium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dismembered Pyeloplasty With and Without After Coming Stent
Status: COMPLETED
Conditions: Pelviureteric Junction Obstruction|Pyeloplasty|Neonatal Hydronephrosis|Obstructive Uropathy|Urinary Stent
Interventions: PROCEDURE: After coming stent after dismembered pyeloplasty|PROCEDURE: Stentless dismembered pyeloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Gilteritinib|DRUG: Ivosidenib|DRUG: Enasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: RSV vaccine formulation 1|BIOLOGICAL: RSV vaccine formulation 2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intermediate Normal Versus High Normal Oxygen Levels in the Emergency Department for Severe Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury|Acute Respiratory Failure|Acute Respiratory Distress Syndrome|Acute Brain Injury
Interventions: OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, 0.015%, in Patients With Photo-damaged Skin
Status: COMPLETED
Conditions: Photo-damage
Interventions: DRUG: PEP005 (ingenol mebutate) Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Consumption of Caraway on Treatment of Obesity
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: caraway sample|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GPX-100 in the Treatment of Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastasis
Interventions: DRUG: GPX-100 (13-deoxydoxorubicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R2 and Combination Chemotherapy Versus R and Combination Chemotherapy in Newly Diagnosed Highly Aggressive B-NHL
Status: UNKNOWN
Conditions: Lymphoma, B-Cell
Interventions: DRUG: R2-combination chemotherapy|DRUG: R-combination chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Concurrent Chemoradiotherapy in Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: COMBINATION_PRODUCT: Toripalimab Combined With Concurrent Platinum-based Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of KZR-616 in Patients With AIHA and ITP
Status: WITHDRAWN
Conditions: Autoimmune Hemolytic Anemia|Immune Thrombocytopenia
Interventions: DRUG: KZR-616
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of PZ-128 in Subjects With Multiple Coronary Artery Disease Risk Factors
Status: COMPLETED
Conditions: Vascular Disease|Coronary Artery Disease Risk Factors Multiple
Interventions: DRUG: PZ-128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Simvastatin, Losartan and Pioglitazone on Patients With Peripheral Arterial Disease.
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Simvastatin|DRUG: Losartan|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk Stratification of Patients Presenting With Upper Gastrointestinal Bleeding to the Emergency Department Using AIMS65 Score and Red Cell Distribution Width
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: OTHER: RISK STRATIFICATION USING AIMS65 SCORE AND RDW
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected Patients
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir|DRUG: Atazanavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Safety and Tolerability Study of Intravenous (IV) and Subcutaneous (SC) AZD1163 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: AZD1163|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2 Clinical Trial to Evaluate the Safety and Efficacy of ConvitVax in Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: ConvitVax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Tumor Vaccine Strategy and PD-1 Blockade in Patients With Follicular Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: BIOLOGICAL: Personalized tumor vaccine|DRUG: Poly ICLC|BIOLOGICAL: Nivolumab|PROCEDURE: Peripheral blood draws|PROCEDURE: Leukapheresis|BIOLOGICAL: Rituximab|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Blueberry Consumption on Gastrointestinal Health
Status: COMPLETED
Conditions: Obesity|Circadian Dysregulation
Interventions: DIETARY_SUPPLEMENT: Blueberry powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Efficacy of Attenuated Zoster Vaccine, Live
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: live attenuated zoster vaccine|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Chronic Total Coronary Occlusion Treatment Results 6 Years After Bioresorbable Scaffold Implantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Angina Pectoris|Coronary Artery Disease|Occlusion, Coronary
Interventions: PROCEDURE: Percutaneous coronary intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating JYP0035 Capsule Monotherapy in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: JYP0035 Experimental Drug Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Ablation Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Combined oral contraceptives (COC)|DRUG: Moxifloxacin 400mg|DRUG: Cenerimod 0.5 mg|DRUG: Cenerimod 4 mg|OTHER: Charcoal, activated|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Placement of Perineural Catheters in the Popliteal Region
Status: UNKNOWN
Conditions: Foot Surgery
Interventions: PROCEDURE: Placement of perineural catheters with Hydrolocalization technique using
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Besifloxacin Ophthalmic Suspension in the Treatment of Bacterial Conjunctivitis
Status: COMPLETED
Conditions: Bacterial Conjunctivitis
Interventions: DRUG: Besifloxacin|DRUG: Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Blockage With Afatinib and Trastuzumab as Neoadjuvant Treatment for Patients With Locally Advanced or Operable Breast Cancer Receiving Taxane-anthracycline Containing Chemotherapy
Status: COMPLETED
Conditions: Unilateral HER2 Positive Breast Cancer
Interventions: DRUG: Afatinib|DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASK-PrEP (Assistance Services Knowledge-PrEP)
Status: RECRUITING
Conditions: Substance Use Disorders|HIV
Interventions: BEHAVIORAL: PrEP navigation + text messaging|BEHAVIORAL: Standard of Care|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zylet vs TobraDex in Blepharokeratoconjunctivitis
Status: COMPLETED
Conditions: Blepharokeratoconjunctivitis
Interventions: DRUG: Loteprednol etabonate and tobramycin ophthalmic suspension|DRUG: Tobramycin and dexamethasone ophthalmic suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ChitoCare Medical Wound Healing Gel PMCF Study on Healing of Chronic Wounds
Status: RECRUITING
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer|Pressure Ulcer
Interventions: DEVICE: ChitoCare medical Wound Healing Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multinomial Process Model of Moral Judgment
Status: COMPLETED
Conditions: Testosterone|Placebos
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: ucMSC|OTHER: Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Retroperitoneal Sarcoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Resection|RADIATION: Spatially-fractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attenuated SOX as First-line Treatment in Elderly Patients With Relapsed or Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Elderly|S-1|Oxaliplatin|First-Line|Gastric Cancer
Interventions: DRUG: S-1 (TS-1) and Oxaliplatin (Oxalitin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBV CAR-T Cells for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: CAR-T Cell Injection|DRUG: Fludarabine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepsera Versus Hepsera Plus Lamivudine for Treatment of Chronic Hepatitis B in Patients With Normal ALT
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Hepsera|DRUG: Hepsera and lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study to Investigate the Safety, PK, and PD of ISU304/CB2679d in Hemophilia B Patients
Status: COMPLETED
Conditions: Hemophilia B
Interventions: BIOLOGICAL: ISU304/CB2679d/Dalcinonacog alfa 75~150 IU/kg|BIOLOGICAL: BeneFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient
Status: COMPLETED
Conditions: Pectus Excavatum
Interventions: DEVICE: ON-Q soaker catheter system|DRUG: Epidural (ropivicaine 0.25%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Furosemide +HSS in Refractory Ascites
Status: COMPLETED
Conditions: Ascites|Cirrhosis
Interventions: DRUG: intravenous furosemide|DRUG: Hypertonic saline solutions|PROCEDURE: Seriated paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Open Label Phase 3 Study of Isatuximab Plus Lenalidomide and Dexamethasone With/Without Bortezomib in the Treatment of Newly Diagnosed Non Frail Transplant Ineligible Multiple Myeloma Elderly Patients (≥ 65; < 80 Years).
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Myeloma
Interventions: DRUG: Isatuximab|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Grapefruit Flavonoid Naringenin for HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus|HCV Infection|Chronic HCV|Hepatitis C
Interventions: DIETARY_SUPPLEMENT: Naringenin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transvertebral Direct Current Stimulation in Humans
Status: TERMINATED
Conditions: Spinal Cord Injuries|Paraplegia and Tetraplegia
Interventions: DEVICE: transvertebral direct current stimulation (tvDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Women With Primary Ovarian Insufficiency (POI)
Status: UNKNOWN
Conditions: Primary Ovarian Insufficiency
Interventions: BIOLOGICAL: Placebo transplantation|BIOLOGICAL: HUC-MSCs transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCT
Status: UNKNOWN
Conditions: Post Operative Adhesions
Interventions: DRUG: Hyaluronic Acid|DRUG: NORMAL SALINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GREM1, HAS2 and PTGS2 Gene Expression Following the in Vitro Maturation (IVM)
Status: RECRUITING
Conditions: Increased Oocyte Death|in Vitro Maturation|GREM1 Gene Mutation|Cumulus Cell
Interventions: GENETIC: cumulus cell oocytes complex (COC) among women with poor ovarian reserve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE