pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Immunogenicity of V116 in Adults Living With Human Immunodeficiency Virus (HIV) (V116-007, STRIDE-7)
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: V116|BIOLOGICAL: Placebo|BIOLOGICAL: PCV15|BIOLOGICAL: PPSV23|BIOLOGICAL: PCV15 - Part B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Extension Study: Evaluating the Safety of Oral Ziprasidone in the Treatment of Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Warning Signs of Squamous Cell Carcinoma and Prevention of SCC by at Risk Organ Transplant Recipients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: BEHAVIORAL: Educational Intervention|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Gut Microbiota in Patients With Urolithiasis
Status: RECRUITING
Conditions: Urolithiasis
Interventions: OTHER: Caloric restriction and control oxalate and citrate foods|OTHER: Caloric restriction|OTHER: Real-life intervention with control oxalate and citrate foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interaction Between a Calcimimetic Agent and the Renin Angiotensine Aldosterone System
Status: COMPLETED
Conditions: Relationship Between Calcimimetic and the RAAS
Interventions: DRUG: Cinacalcet 60 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: OCD
Interventions: DRUG: escitalopram|DRUG: Placebo ( sugar pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Pembrolizumab With TGR-1202 in Patients With Relapsed/Refractory CLL and B-cell NHL
Status: ACTIVE_NOT_RECRUITING
Conditions: CLL|B-cell Non Hodgkin Lymphoma
Interventions: DRUG: TGR-1202|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: BIOLOGICAL: Platelet Rich Plasma for 4 sessions|BIOLOGICAL: Platelet rich plasma for 2 sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Controlled Trial to Reduce Salt Intake Among Hypertensive Young Adults in Hong Kong
Status: TERMINATED
Conditions: Hypertension
Interventions: BEHAVIORAL: Four-week weekly intervention to reduce salt intake|OTHER: Usual government pamphlets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dehydrated Human Amnion Chorion Membrane (dHACM) vs. Control in the Treatment of Partial Thickness Burns.
Status: TERMINATED
Conditions: Treatment of Partial Thickness Burns
Interventions: OTHER: Dehydrated Human Amnion/Chorion Membrane|DEVICE: Mepilex Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taurine Supplementation on Lower Extremity Vasculopathy in Patients With Diabetes
Status: UNKNOWN
Conditions: Taurine|Diabetes|Lower Extremity Artery Disease
Interventions: DRUG: Taurine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leveraging mHealth and Peers to Engage African- Americans and Latinxs in HIV Care (LEAN)
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: mLTCR|BEHAVIORAL: LTCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Follow-up Gun Study: Can Safety Videos Mitigate Interest in Guns in Children?
Status: UNKNOWN
Conditions: Psychology, Social|Adolescent Behavior
Interventions: BEHAVIORAL: Gun handling behavior|OTHER: Debriefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Compare Apatinib Plus Irinotecan Versus Single Irinotecan as Second-line Treatment in AGC or EGJA
Status: UNKNOWN
Conditions: Advanced Gastric Cancer Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: Apatinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Clopidogrel on Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure|Endothelial Function|Platelet Function
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel|DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CLARITY Extension Study
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Cladribine|DRUG: Placebo|DRUG: Cladribine|DRUG: Cladribine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Eltrombopag|DRUG: Steroids|DRUG: IVIG|DRUG: Rho(D) Immune Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Trifluridine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200
Status: COMPLETED
Conditions: Absorption, Metabolism and Excretion in Healthy Volunteers
Interventions: DRUG: [14C]-PBI-200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Single-incision Thoracoscopic Surgery
Interventions: COMBINATION_PRODUCT: general anesthesia|COMBINATION_PRODUCT: epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effect of Morphine Added to Transverses Abdominis Plane Block
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Complications
Interventions: PROCEDURE: Group ıntramuscular|PROCEDURE: Group TAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fecal Microbiota Transplant (FMT) for Relapsing C. Difficile Infection in Adults and Children Using a Frozen Inoculum
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Fecal Microbiota Transplant (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunomodulatory Therapy in Women With Autoimmune Premature Ovarian Insufficiency
Status: RECRUITING
Conditions: Autoimmune Diseases|Premature Ovarian Insufficiency
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-week Evaluation of GSK573719/Vilanterol (125/25mcg) and Components in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719/GW642444 125/25mcg|DRUG: GSK573719 125mcg|DRUG: GW642444 25mcg|DRUG: Placebo only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Cognitive Behavioral Analysis System of Psychotherapy (CBASP) and System of Supportive Psychotherapy (SYSP) for Early Onset Chronic Depression
Status: COMPLETED
Conditions: Chronic Major Depressive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Analysis System of Psychotherapy|BEHAVIORAL: System of Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects
Status: COMPLETED
Conditions: Malignancies Multiple
Interventions: DRUG: BMS-986205|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Lymphoma
Interventions: COMBINATION_PRODUCT: Drugs and Anti-CD19-CAR transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Appropriate Sedation for Patients After Gastrectomy: A Prospective Randomised Controlled Study
Status: UNKNOWN
Conditions: Postoperative Sedation,Gastrectomy, Enhanced Recovery After Surgery
Interventions: DRUG: dexmedetomidine, tramadol and flurbiprofen|DRUG: tramadol and flurbiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Shared Medical Appointment Intervention for Quality of Life Improvement in POTS
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: BEHAVIORAL: Shared medical appointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Pain
Status: UNKNOWN
Conditions: Postherpetic Neuralgia|Neuralgia
Interventions: DRUG: Etoricoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
Status: RECRUITING
Conditions: Macular Disease|Rhegmatogenous Retinal Detachment|Epiretinal Membrane|Cataract|Vitreous Hemorrhage|Vitreomacular Traction|Vitreous Cloudy
Interventions: PROCEDURE: FLACS +PPV+IOL + air|PROCEDURE: FLACS +PPV+IOL + epiretinal membrane peeling + Ozurdex|PROCEDURE: FLACS + PPV+IOL + internal limiting membrane peeling + air|PROCEDURE: FLACS + PPV+IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin 250mg/5mL NDC:59762-5025-01|DRUG: Simple Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First-in-Human Study of BMS-986421 in Healthy Participants
Status: TERMINATED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986421|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vaniprevir Plus PegIntron®/Ribavirin in Japanese Participants With Chronic Hepatitis C Who Relapsed After Treatment (MK-7009-044)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: vaniprevir|BIOLOGICAL: peg-IFN|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Relations for Health Effects Caused by Office Dust
Status: COMPLETED
Conditions: Discomfort Symptoms|Changed Lung Function
Interventions: OTHER: Office dust|OTHER: clean air
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Atezolizumab (Anti-Pd-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Interventions: DRUG: Atezolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Serratus Anterior Plane Block With Dexmedetomidine During Breast Surgery
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Single level serratus anterior plane block|PROCEDURE: Single level serratus anterior plane block with dexmedetomidine|PROCEDURE: Bilevel serratus anterior plane block|PROCEDURE: Bilevel serratus anterior plane block with dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Infiltration of Medical Ozone for the Treatment of Medication-Related Osteonecrosis of the Jaws (MRONJ)
Status: SUSPENDED
Conditions: MEDICATION RELATED OSTEONECROSIS OF THE JAW
Interventions: DRUG: OZOPROMAF_SEQ1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial
Status: COMPLETED
Conditions: Hypertension|Pre-Hypertension
Interventions: OTHER: Isometric Handgrip Training|OTHER: Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigator-initiated Trial to Assess the Effectiveness of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children
Status: COMPLETED
Conditions: Healthy Children
Interventions: DIETARY_SUPPLEMENT: Curcumin Gummies|DIETARY_SUPPLEMENT: Vitamin C Gummies|DIETARY_SUPPLEMENT: Multivitamin Gummies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary Chemotherapy
Status: TERMINATED
Conditions: Thymoma|Advanced Thymic Epithelial Tumor
Interventions: DRUG: Open Label Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fesoterodine "add-on" Male Overactive Bladder Study
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: Fesoterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Neck Locking Plate Vs Multiple Cannulated Cancellous Screws in Treatment of Femoral Neck Fractures in Young Adults: Randomized Controlled Clinical Trial Study
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures
Interventions: DEVICE: femoral neck locking plate|DEVICE: multiple cannulated cancellous screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Autoimmunity Withdrawn In New Onset and In Established Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: TOL-3021|OTHER: TOL-3021 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Limb Lengths in Gastric Bypass Surgery (SLIM) - Part 3: Metabolism and Inflammation
Status: RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Long Biliopancreatic Limb LRYGB|PROCEDURE: Short Biliopancreatic Limb LRYGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anlotinib hydrochloride capsules, Penpulimab injection|DRUG: Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Versus Conventional Method for Caudal Block
Status: COMPLETED
Conditions: Ultrasound Therapy; Complications
Interventions: DRUG: Bupivacaine|DRUG: Adrenalin|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison of Incidence of Heavy Menstrual Bleeding in Women Treated With Direct Oral Anticoagulants
Status: COMPLETED
Conditions: Heavy Menstrual Bleeding
Interventions: DRUG: Apixaban 5 MG|DRUG: Rivaroxaban 20 MG|DRUG: Edoxaban 60 MG|DRUG: Dabigatran 150 Mg Oral Capsule
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PMI Guide PS Setting in Pressure Support-ventilated Patients
Status: RECRUITING
Conditions: Mechanical Ventilation
Interventions: PROCEDURE: PS setting strategy in pressure-support ventilated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natural Gels for Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Parapsoriasis
Interventions: DRUG: natural gels|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Filibuvir In Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Subjects
Status: COMPLETED
Conditions: Hepatitis|Hepatitis C
Interventions: DRUG: Filibuvir|DRUG: Filibuvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bortezomib and Docetaxel for Patients With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: PS 341|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: IMVAMUNE®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: External Beam Radiation Therapy Post Surgery in Patients With Lower Extremity Bone Metastases Randomized Efficacy Trial
Status: WITHDRAWN
Conditions: Bone Metastases|Lower Extremity Fracture|Pathological Fracture|Impending Fracture
Interventions: RADIATION: External beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Rec 0/0438 in Patients With Neurogenic Detrusor Overactivity Due to Spinal Cord Injury
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Rec 0/0438 1 mg or Rec 0/0438 2 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCT
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Acute Lymphocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Fludarabine|RADIATION: Total Marrow Irradiation (TMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
Status: RECRUITING
Conditions: Venous Sinus Thrombosis, Cranial
Interventions: DIAGNOSTIC_TEST: anotomy and variation of venous sinus|DIAGNOSTIC_TEST: the level of biomarker in bood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Risperidone Treatment In Children With Autism Spectrum Disorder And High Levels Of Repetitive Behavior
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Yoga for Older Adults and Caregivers
Status: NOT_YET_RECRUITING
Conditions: Psychological
Interventions: BEHAVIORAL: Mindful yoga|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sublingual Immunotherapy Studies for Grass and Dust Mite Allergies
Status: COMPLETED
Conditions: Allergies|Allergic Rhinitis|Asthma
Interventions: DRUG: sublingual immunotherapy|DRUG: placebo sublingual immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Assessing the Effect of Lymphaticovenous Micro-Anastomosis in the Treatment of Postmastectomy Lymphedema
Status: TERMINATED
Conditions: Lymphedema|Post Mastectomy
Interventions: PROCEDURE: Lymphaticovenous Micro-Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Delafloxacin Versus Ceftriaxone for the Treatment of Uncomplicated Gonorrhea
Status: TERMINATED
Conditions: Gonorrhea
Interventions: DRUG: Delafloxacin|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose, Repeated Dose, and Conditional Food Effect Study of PF-05221304 in Healthy Subjects
Status: COMPLETED
Conditions: Normal Healthy
Interventions: DRUG: PF-05221304|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Medial-Wedge Insole is Highly Effective in the Treatment of Valgus Knee Osteoarthritis
Status: TERMINATED
Conditions: Osteoathritis
Interventions: PROCEDURE: Medial-Wedge Insole intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PAC-IC-SAS Pilot Study - Central Sleep Apneas Syndrome and Ventricular Function
Status: COMPLETED
Conditions: Central Sleep Apneas Syndrome|Heart Failure|Coronary Artery Bypass Graft Surgery or Other Coronary Reperfusion
Interventions: PROCEDURE: Adaptive servo-ventilation post-operative treatment for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
Status: COMPLETED
Conditions: Cataract|Refractive Error
Interventions: DEVICE: TECNIS Symfony plus IOL Model ZHR00V|DEVICE: Trifocal Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Repeat Ascending Doses of GSK2018682 in Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: GSK2018682|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Aspirin|DRUG: Tirofiban|DRUG: Clopidogrel|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Role of Doulas in Supporting People With PMADs
Status: NOT_YET_RECRUITING
Conditions: Maternal Health|Pregnancy|Delivery, Obstetric|Self Efficacy|Social Support|Mental Health|Substance-Related Disorders|Postpartum Depression|Depression|Mental Health Services
Interventions: BEHAVIORAL: Standard Doula Care Plus PMAD Intervention|BEHAVIORAL: Standard Doula Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating Preventive Therapy With Oint Threolone, Synthomycine or Aqua Cream, for EGFR'I Induced Acneiform Rash
Status: COMPLETED
Conditions: Acneiform Rash
Interventions: DRUG: Threolone ointment|DRUG: ointment Synthomycine|DRUG: Aqua cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8|Metastatic Castration-resistant Prostate Carcinoma|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Abemaciclib|DRUG: Lutetium Lu 177-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Long-pulsed 1064 nm nd: Yag Laser-assisted Hair Removal on Some Skin Flora and Pathogens: an in Vivo Study
Status: UNKNOWN
Conditions: Changes in Bacterial Count in Axilla After Laser Hair Removal
Interventions: DEVICE: ND;YAG 1064NM LASER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate the Efficacy and Safety of HOB-048 CR Tab. in Comparison With HOB-048 Syrup in Patients With Cough Due to Acute or Chronic Bronchitis
Status: COMPLETED
Conditions: Evaluate the Efficacy and Safety of Levotuss CR Tab. in Comparison With Levotuss Syrup in Patients With Cough Due to Acute or Chronic Bronchitis
Interventions: DRUG: Levotuss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Precancerous Condition
Interventions: DRUG: pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Assess the Safety and Tolerability of MTx-COVAB36 as a Therapeutic and Prophylactic Treatment Against COVID-19.
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: MTx-COVAB36|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine for the Treatment of Methamphetamine Use in Opioid Use Disorder Patients Receiving Medication Assisted Treatment
Status: RECRUITING
Conditions: Stimulant Use Disorder
Interventions: DRUG: Mirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Time-restricted Eating for Postpartum Weight Loss
Status: NOT_YET_RECRUITING
Conditions: Postpartum Weight Retention|Overweight and Obesity
Interventions: BEHAVIORAL: Early Time-Restricted Eating (eTRE)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Irinotecan and cisplatin|DRUG: Etoposide and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Aromatase Inhibitor|DRUG: Induction Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celiac Disease in Childhood-Adulthood Transition
Status: ENROLLING_BY_INVITATION
Conditions: Celiac Disease|Celiac Disease in Children|Transition of Care|Follow-up|Diet, Gluten-Free
Interventions: OTHER: CeliCAT form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genetic Characteristics of HER2 Positive Breast Cancer With Neoadjuvant TCHP Chemotherapy
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer|Chemotherapy Effect|Circulating Tumor DNA
Interventions: DIAGNOSTIC_TEST: LiquidSCAN(Trade Mark) / CancerSCAN(Trade Mark)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerogenic Dendritic Cells as a Therapeutic Strategy for the Treatment of Multiple Sclerosis Patients (TOLERVIT-MS)
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Chronic Progressive
Interventions: DRUG: Autologous VitD3 tolerogenic monocyte-derived dendritic cells loaded with a pool of myelin peptides (tolDC-VitD3)|DRUG: Interferon-beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ACTIVE (Use of the Assurant® Cobalt Iliac Stent System in the Treatment of Iliac Vessel Disease) Study
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Assurant® Cobalt Iliac Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Etelcalcetide on CKD-MBD
Status: COMPLETED
Conditions: Chronic Kidney Disease Mineral and Bone Disorder|Renal Osteodystrophy|Vascular Calcification|Hyperparathyroidism; Secondary, Renal
Interventions: DRUG: Etelcalcetide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POP-UP: a Single-arm, Two-cohort Study: Trimodal Prehab for Upper GI and Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Esophageal Cancer
Interventions: OTHER: Prehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Reversibility of Cardiac Conduction Disturbances Following TAVI
Status: RECRUITING
Conditions: Aortic Stenosis|Transcatheter Aortic Valve Implantation|Conduction Disturbances
Interventions: DIAGNOSTIC_TEST: Electrophysiological study (EP study)|DIAGNOSTIC_TEST: ePatch (extended Holter Monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Daily Single Shot Adductor Canal Block Versus Continuous Adductor Canal Block After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Single shot adductor canal block|PROCEDURE: Continuous adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Comparative Effectiveness of Stroke Prevention in Patients With Atrial Fibrillation Treated With Factor Xa Non-vitamin-K Oral Anticoagulants (NOACs) vs. Phenprocoumon
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Phenprocoumon|DRUG: Apixaban|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Edoxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the Aorta
Status: COMPLETED
Conditions: Congenital Heart Disease|Aortic Coarctation|Cardiovascular Disease
Interventions: OTHER: Image-based simulation modelling|OTHER: Imaging parameters currently recommended by clinical practice guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: REnal SympathetiC Denervation to sUpprEss Tachyarrhythmias in ICD Recipients
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Boston Scientific Vessix Renal Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension Study of AMG 531 in Japanese Subjects With ITP
Status: COMPLETED
Conditions: Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Interventions: BIOLOGICAL: AMG 531
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIBP (Non-invasive Blood Pressure) Algorithm Enhancements (Characterize the Robustness of Motion Artifact Suppression)
Status: TERMINATED
Conditions: Movement, Involuntary
Interventions: DEVICE: Philips IntelliVue X3 patient monitor with investigational NIBP measurement algorithm (measured once per 3 minutes)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SAFEty of Two Strategies of ICD Management at Implantation
Status: COMPLETED
Conditions: Ventricular Fibrillation|Ventricular Flutter|Sudden Cardiac Death
Interventions: DEVICE: Implantable defibrillator|DEVICE: Implantable defibrillator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Pharmacokinetics, Safety and Immunogenicity of CT-P6 and US-licensed Herceptin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Purified Inactivated Japanese Encephalitis Vaccine
Status: UNKNOWN
Conditions: Japanese Encephalitis Virus Disease
Interventions: BIOLOGICAL: Japanese Encephalitis Vaccine produced by IMBCAMS|BIOLOGICAL: Japanese Encephalitis Vaccine produced by Liaoning Chenda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II/III of Randomized Controlled Clinical Research on IRE Synchronous Chemotherapy for LAPC
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Adenocarcinoma
Interventions: DEVICE: Irreversible electroporation|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Neuromuscular Electrical Stimulation to Attenuate Muscle Loss
Status: COMPLETED
Conditions: Muscle Disuse|Neuromuscular Electrical Stimulation (NMES)|Critical Illness
Interventions: PROCEDURE: Neuromuscular Electrical Stimulation of m. quadriceps femoris|PROCEDURE: Sham-treatment: no NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide Plus Chemotherapy for AML
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Mitoxantrone|DRUG: Etoposide|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Freshwater Clam Extract on Blood Sugar, and Lipid Profile in Prediabetes Patients
Status: UNKNOWN
Conditions: Prediabetes|Metabolic Diseases|Glucose Metabolism Disorders|Dietary Supplement|Nutrition
Interventions: DIETARY_SUPPLEMENT: clam protein capsules|DIETARY_SUPPLEMENT: Clam peptide plus Chlorella capsules|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Live Instruction and Fitness Tracking*: A 12-week Combined Aerobic and Resistance Training Intervention
Status: COMPLETED
Conditions: Physical Inactivity|Health Risk Behaviors
Interventions: BEHAVIORAL: Live Instruction and Fitness Tracking (LIFT-up)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy of Ramosetron on Diarrhea-predominant Irritable Bowel Syndrome (IBS) in Male Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Ramosetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarcoidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: Efzofitimod 3 mg/kg|DRUG: Efzofitimod 5 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of T+A+RAD in HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Multifocal Stereotactic Radiotherapy|DRUG: Atezolizumab Injection [Tecentriq]|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Health and Recovery in Older Adults
Status: RECRUITING
Conditions: Muscle Injury
Interventions: OTHER: Control Liquid Supplement|OTHER: Experimental Liquid Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Long-term Follow-up Study of Sotatercept for PAH Treatment (MK-7962-004/A011-12)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension|PAH
Interventions: BIOLOGICAL: Sotatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Safety and Efficacy of YPEG-rhG-CSF in Malignancies Receiving Chemotherapy
Status: COMPLETED
Conditions: Non-Myeloid Malignancy
Interventions: DRUG: YPEG-rhG-CSF|DRUG: YPEG-rhG-CSF|DRUG: rhG-CSF/PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Using a Chatbot to Promote Adherence to Home Physiotherapy
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Chatbot Assistant|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer Disease
Status: UNKNOWN
Conditions: Alzheimer Disease|Transcranial Magnetic Stimulation
Interventions: DEVICE: repetitive transcranial magnetic stimulation- IDLPFC|DEVICE: repetitive transcranial magnetic stimulation - Six regions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid
Status: UNKNOWN
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Teriparatide Pen Injector|DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic and Cerebral Effects Evaluation in Anesthesia
Status: RECRUITING
Conditions: Hemodynamic Monitoring|Orthopedic Procedures
Interventions: DEVICE: hemodynamic continuous monitoring|DEVICE: Standard Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Grip Strength by Using Bandage Kinesio Taping
Status: COMPLETED
Conditions: Hand Strength
Interventions: OTHER: Kinesio Taping® bandage|OTHER: Dynamometer Jamar® pressure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Percutaneous Neuromodulation on the Anterior Pain Knee
Status: COMPLETED
Conditions: Neuromodulation|Anterior Pain Knee|Femoral Nerve
Interventions: OTHER: PNM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants
Status: COMPLETED
Conditions: Lymphoma|Myeloma|Leukemia|Myelodysplasia|Solid Tumors|Hodgkin's Disease|Myelofibrosis
Interventions: PROCEDURE: Total Body Irradiation with Fludarabine in UCB Transplants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of CymActive™ Catheter Technology for UrinAry ReTention and AcceptancE (The ACCTUATE Study)
Status: NOT_YET_RECRUITING
Conditions: Urinary Retention
Interventions: DEVICE: cymactiv catheter device|DEVICE: Foley-type catheter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Regression of Liver Fibrosis and Risk for Hepatocellular Carcinoma (ROLFH) Study
Status: WITHDRAWN
Conditions: Chronic Hepatitis C|Chronic Hepatitis B
Interventions: OTHER: Regression of fibrosis|OTHER: Specific risk factors related to hepatocellular carcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: Placebo|DRUG: Erenumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Armodafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Vasopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE