pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combined Vaginal Misoprostol and Perivascular Vasopressin
Status: COMPLETED
Conditions: Leiomyoma|Laparoscopy|Uterine Myomectomy
Interventions: DRUG: Standard|DRUG: Standard-vaginal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Orteronel Plus Prednisone in Participants With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Orteronel|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of a Plague Vaccine, Flagellin/F1/V, in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Plague
Interventions: BIOLOGICAL: Flagellin/F1/V|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cladribine vs Placebo for Non-active Progressive Multiple Sclerosis (CLASP-MS).
Status: RECRUITING
Conditions: Multiple Sclerosis, Secondary Progressive|Multiple Sclerosis
Interventions: DRUG: Cladribine Subcutaneous Injection|DRUG: 0.9% Chloride Injection Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space
Status: TERMINATED
Conditions: Visual Neglect
Interventions: OTHER: Cathodal tDCS|OTHER: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PENG vs. QLB vs. Lumbar ESPB in Total Hip Surgery
Status: RECRUITING
Conditions: Total Hip Surgery|Pericapsular Nerve|Quadratus Lumborum|ESPB
Interventions: PROCEDURE: PENG block Technique|PROCEDURE: Lumbar ESPB Technique|PROCEDURE: Transmuscular QLB-t block Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in Children Having Transthoracic Echocardiography
Status: COMPLETED
Conditions: Heart Disease
Interventions: DRUG: Chloral Hydrate|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The COPPER-B Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases|Peripheral Vascular Disease|Arterial Occlusive Diseases|Peripheral Arterial Disease|Critical Limb Ischemia
Interventions: OTHER: Paclitaxel administration using the OPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heterogeneity of Metastatic Neuroendocrine Tumors as Determined With 18F-dihydroxyphenylalanine-PET /CT, a Retrospective Analysis
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: OTHER: Metastasized intestinal NET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Web-based Follow-up to Former ICU Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Intensive Care Unit Syndrome
Interventions: BEHAVIORAL: Web-based follow-up programme.|BEHAVIORAL: No follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metformin as a Neuroprotective Therapy for Glaucoma - A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Glaucoma
Interventions: DRUG: Metformin|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine vs. Ketorolac/ Midazolam for Retinal Surgery
Status: COMPLETED
Conditions: Retinal Surgery
Interventions: DRUG: Dexmedetomidine group (D)|DRUG: Ketorolac-Midazolam group (KM)|DRUG: Control group (Normal Saline) (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Status: ACTIVE_NOT_RECRUITING
Conditions: Proteomics|Exercise|Atrophy, Disuse|Hypertrophy
Interventions: PROCEDURE: Knee bracing|OTHER: Unilateral Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture Treatment of Chemotherapy-Induced Peripheral Neuropathy in Women
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy|Breast Cancer Female|Gynecologic Cancer
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Excitatory rTMS to the Left Dorsolateral Pre-Frontal Cortex to Reduce Cannabis-Cue Induced Craving
Status: COMPLETED
Conditions: Cannabis
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3D-printed Crowns Versus Zirconia Crowns for Primary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries in Children
Interventions: OTHER: 3D printed crowns|OTHER: Zirconia crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies.
Status: COMPLETED
Conditions: Dementia With Lewy Bodies|Degeneration Nerves|Positron-Emission Tomography|Acetylcholine
Interventions: RADIATION: PET-CT using FEOBV|RADIATION: MRI-scan|DIAGNOSTIC_TEST: Cognitive assessment|DIAGNOSTIC_TEST: Clinical assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Spinal Anesthesia Versus Combined Spinal Epidural Block
Status: UNKNOWN
Conditions: Hip Fractures|Knee Arthroplasty|Femur Fracture
Interventions: PROCEDURE: continuous spinal anesthesia|PROCEDURE: Spinocath a catheter for continuous spinal anesthesia|PROCEDURE: combined spinal epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss
Status: COMPLETED
Conditions: Coronavirus Infection|COVID|Severe Acute Respiratory Syndrome|Respiratory Failure|Respiratory Insufficiency|Respiratory Distress Syndrome|ARDS|Lung Diseases
Interventions: PROCEDURE: Awake Prone Positioning|PROCEDURE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma
Status: COMPLETED
Conditions: Recurrent or Progressive Malignant Glioma
Interventions: DRUG: ANG1005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Remote Self-care Education for Ostomy Patients
Status: RECRUITING
Conditions: Ostomy
Interventions: BEHAVIORAL: Remote self-care education|BEHAVIORAL: In-person self-care education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: WHO COVID-19 - Evaluation of the Efficacy of Probiotics to Reduce the Occurrence of Long COVID
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Neoplasms|Breast Cancer
Interventions: RADIATION: Ten-fraction hypofractionated breast radiotherapy with 40 Gy simultaneous integrated bed boost|RADIATION: Ten-fraction hypofractionated breast radiotherapy with 43 Gy simultaneous integrated bed boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of a 4-month Daily Regimen (2HZPM/2HPM) for Treatment of Pulmonary TB
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: 4-month rifapentine-based regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Duration Between Sessions on Microperimetric Biofeedback Training in Patients With Maculopathies
Status: COMPLETED
Conditions: Macular Degeneration|Low Vision|Stargardt Disease
Interventions: PROCEDURE: microperimetric biofeedback training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capravirine (AG1549) in Combination With Viracept and Two NRTIs in HIV Infected Patients Who Failed an Initial NNRTI Containing Regimen
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Capravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Designing Multimedia Patient Education for Adolescent Idiopathic Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis|Patient Engagement
Interventions: OTHER: Traditional video format|OTHER: Evidence-informed video format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Different Doses of Ipratropium Bromide Versus ATROVENT® Inhalation Aerosol in Adults With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Low dose of Ipratropium bromide|DRUG: High dose of Ipratropium bromide|DRUG: Atrovent|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor
Status: COMPLETED
Conditions: Advanced Cancers|Sarcoma
Interventions: PROCEDURE: Hyperthermic Peritoneal Perfusion (HIPEC)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Status: COMPLETED
Conditions: Total Knee Arthoplasty|Knee Pain
Interventions: OTHER: Routine Physical Therapy and Intra-venous analgesic regimen|OTHER: Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans?
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olive Oil Polyphenols, Vitamin D, Docosahexaenoic Acid (DHA) and Locomotor Function (PolivD3)
Status: COMPLETED
Conditions: Osteopenia|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Low level light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer
Status: COMPLETED
Conditions: Colon Cancer|Pancreatic Cancer|Perioperative/Postoperative Complications|Primary Peritoneal Cavity Cancer|Rectal Cancer
Interventions: PROCEDURE: wound care management|PROCEDURE: wound care management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease
Status: RECRUITING
Conditions: Congenital Heart Disease|Thiamine Deficiency|Patent Ductus Arteriosus|Ventricular Septal Defect|Atrial Septal Defect
Interventions: DRUG: Thiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Comprehensive Rehab Program and Pelvic Floor Training in Women With Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: OTHER: Comprehensive Rehabilitation Program|OTHER: Conventional Pelvic Floor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Nurse Caring Behavior Protocol on Postoperative Cardiac Patient Satisfaction
Status: COMPLETED
Conditions: Nurse-Patient Relations|Patient Satisfaction|Caring
Interventions: OTHER: A nurse caring behavior protocol|OTHER: Routine nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder
Status: TERMINATED
Conditions: Opiate Dependence|Chronic Pain
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Three Formulations of Dengue Vaccines in Healthy Adults Aged 18 to 45 Years in the US
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Dengue Virus
Interventions: BIOLOGICAL: Tetravalent CYD Dengue Vaccine , 5555 formulation|BIOLOGICAL: Tetravalent CYD Dengue Vaccine , 5553 formulation|BIOLOGICAL: Tetravalent CYD Dengue Vaccine, 4444 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Sub-mental Ultrasonography in Diagnosing Obstructive Sleep Apnea and Its Correlation With Subjective Scales
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Diagnostic Imaging|Ultrasound
Interventions: DIAGNOSTIC_TEST: Sub-mental ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Hemochromatosis|Myelodysplastic Syndromes
Interventions: DRUG: Deferasirox|OTHER: Venesection|DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LVAD in Non Cardiac Transplant Candidates and Non Responders to Resynchronization
Status: WITHDRAWN
Conditions: Heart Failure at NYHA Stage III or IV|Non Responders to Resynchronization|Non Candidates for Transplantation
Interventions: DEVICE: heart mate II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LY2181308 in Combination With Docetaxel Versus Docetaxel in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: LY2181308
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Moderate to Severe Rheumatoid Arthritis Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Baricitinib|DRUG: cDMARD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Tuberculosis Intradermal Skin Test
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Medical device : micro-needle BD 1.5 mm 30G drug:Tubertest® : tuberculin (purified protein derivative)|DEVICE: medical device: lance 26G X 16mm drug: Tubertest® : tuberculin (purified protein derivative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Castor Bean Solution for Cleaning Dentures
Status: COMPLETED
Conditions: Prostheses-related Infections
Interventions: OTHER: Physiological solution|OTHER: Sodium hypochlorite|OTHER: Alkaline Peroxide|OTHER: Castor bean solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: D2560C00015 FluMist Annual Safety Study 2018
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Bivalent influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial)
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: ruxolitinib tablets|OTHER: Best Available Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Kaltenborn End Range Joint Mobilization Technique and Post FacilitationStretch in Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: KAlternborn Joint Mobilization|OTHER: Post stretch Facilitation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of a Palliative Care Intervention to Improve Kidney Therapy Decision-Making for Older People With Advanced Chronic Kidney Disease (CKD)
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: CKD-EDU|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injection (Lipodox®) in Chinese Patients
Status: UNKNOWN
Conditions: Breast Cancer|Ovarian Cancer
Interventions: DRUG: Doxorubicin Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Soft Tissue Sarcoma
Interventions: DRUG: Standard arm: Trabectedin in monotherapy|DRUG: Experimental arm: Trabectedin + Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Oral Insulin in T2DM Patients With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: ORMD-0801 (Insulin) capsule 8 mg BD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Body Healthy Souls in the Marshallese Population
Status: COMPLETED
Conditions: Weight Loss|Pre Diabetes|Overweight and Obesity
Interventions: BEHAVIORAL: HBHS|BEHAVIORAL: HBHS Policy|BEHAVIORAL: WORD DPP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Functional Residual Capacity and Alveolar Recruitment in Single-lung Ventilation: a Randomized Study
Status: NOT_YET_RECRUITING
Conditions: Lung Injury
Interventions: PROCEDURE: VPFE monitoring with intraoperative alveolar recruitment maneuvers.|PROCEDURE: VPFE monitoring with intraoperative alveolar recruitment maneuvers.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Three-dimensional Exercise (Schroth Exercise) on Diaphragm Thickness in Adolescent Idiopathic Scoliosis Patients
Status: RECRUITING
Conditions: Spine Deformity|Scoliosis|Scoliosis Idiopathic|Scoliosis; Adolescence|Diaphragm Issues
Interventions: DIAGNOSTIC_TEST: Scoliosis study form|DIAGNOSTIC_TEST: Scoliosis X-ray (orthorontgenogram)|DIAGNOSTIC_TEST: Pulmonary function test|DIAGNOSTIC_TEST: Ultrasonographic Measurement|PROCEDURE: Three-dimensional Exercise (BSPTS Schroth Exercise)|PROCEDURE: Home Exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Cartilage Degeneration
Interventions: OTHER: lower-body positive-pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Double Blind Clinical Trial of DCS for Food Anxiety
Status: COMPLETED
Conditions: Anorexia and Bulimia Nervosa
Interventions: DRUG: Placebo vs Setraline|DRUG: Setraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study
Status: COMPLETED
Conditions: Congenital Heart Defect|Executive Function|Children|Neurodevelopmental Disorders|Working Memory|Infant Open Heart Surgery
Interventions: BEHAVIORAL: Cogmed Working Memory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Simulated Clinical Use Testing On Safety Lancets (Test B)
Status: COMPLETED
Conditions: Needle Stick
Interventions: DEVICE: Haemolance Plus safety lancet|DEVICE: Prolance safety lancet|DEVICE: MediSafe Solo safety lancet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Ulistin on Acute Renal Injury in Patients Undergoing OPCAB (Off Pump Coronary Artery Bypass): a Propensity Score Matched Study
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Ulinastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brain Aneurysms: Utility of Cisternal Urokinase Irrigation
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Vasospasm, Cerebral|Hydrocephalus
Interventions: DRUG: Urokinase|PROCEDURE: Endovascular treatment|PROCEDURE: Clipping|PROCEDURE: External ventricular drain
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2a of RSLV-132 in Subjects With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: RSLV-132|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Depressive Symptoms Through Personalised Exercise and Activation
Status: RECRUITING
Conditions: Depressive Symptoms|Depressive Disorder
Interventions: BEHAVIORAL: IDEA program (Improving depressive symptoms through personalised exercise and activation)|DEVICE: IDEApp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain
Status: COMPLETED
Conditions: Pancreatitis, Chronic|Pancreatitis, Acute Recurrent
Interventions: BEHAVIORAL: Internet-based CBT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Iguratimod Compared to Placebo in Patients With Active Primary Sjogren's Syndrome.
Status: UNKNOWN
Conditions: Primary Sjögren Syndrome
Interventions: DRUG: Iguratimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: autologous dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Clinical Efficacy and the Changes of Immune Cells Subsets With Bioagents in Ankylosing Spondylitis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Secukinumab 150 mg/ml|DRUG: Adalimumab Ab|DRUG: NSAID|DRUG: Thalidomide Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLAN Intervention to Enhance Engagement of Latino Cancer Patients in Advanced Care Planning
Status: RECRUITING
Conditions: Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: OTHER: Communication Intervention|OTHER: Best Practice|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Axillary Reverse Mapping Using Methylene Blue Subcutaneous Injection Can Identify Arm Lymph Nodes and Vessels, Measuring Arm Size for Lymphedema, Histopathological Examination of Arm Lymph Nodes Included With Axillary Lymph Node Dissection
Status: COMPLETED
Conditions: Arm Lymphedema|Lymphatic Spread of Breast Cancer|Early Breast Cancer
Interventions: PROCEDURE: AXILLARY REVERSE MAPPING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Scandinavian Sarcoma Group Protocol for Patients With High-risk Soft Tissue Sarcoma of the Extremities and Trunk Wall
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma|Non Metastatic Disease
Interventions: DRUG: doxorubicin , ifosfamide|DRUG: doxorubicin, ifosfamide|DRUG: doxorubicin, ifosfamide|DRUG: doxorubicin, ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Etanercept Before Inguinal Hernia Surgery
Status: COMPLETED
Conditions: Inguinal Hernia|Postoperative Pain
Interventions: DRUG: Etanercept|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spine Procedures Assisted With RoboTics And Navigation
Status: RECRUITING
Conditions: Spine Deformity|Idiopathic Scoliosis|Adolescent Idiopathic Scoliosis|Spondylolisthesis|Congenital Scoliosis|Neuromuscular Scoliosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug-Drug Interaction Study to Evaluate the Pharmacokinetics and Safety of CTX 4430 and Midazolam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CTX-4430|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Efficacy of KT vs DN With Conventional Treatment for Improving QOL and Alleviating Pain in Frozen Shoulder
Status: ACTIVE_NOT_RECRUITING
Conditions: Frozen Shoulder
Interventions: DIAGNOSTIC_TEST: Kinesio taping|DIAGNOSTIC_TEST: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rituximab Plus Bendamustine as Front Line Treatment in Frail Elderly (>70 Years) Patients With DLBCL: a Phase II Multicenter Study of the FIL
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Bendamustine+Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Switching From Retrovir to Tenofovir or Abacavir in HIV-infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir disoproxil fumarate|DRUG: Abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic (PK) Study of Nilotinib in Pediatric Patients With Philadelphia Chromosome-positive (Ph+) Chronic Myelogenous Leukemia (CML) or Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug Metabolis/Transport Pharmacogenetics in the Prediction of Response and Treatment Outcomes in Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Patients With Acute Myeloid Leukemia|Patients Receiving Induction/Consolidation Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 4 Study to Assess the Impact of Patient Support Program on Health Related Quality of Life and Adherence in Subjects With Relapsing-Remitting Multiple Sclerosis Administered Rebif® With the RebiSmart™ Device
Status: COMPLETED
Conditions: Multiple Sclerosis|Relapsing-Remitting
Interventions: DRUG: Rebif®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk
Status: NOT_YET_RECRUITING
Conditions: Overweight|Obesity|Metabolic Syndrome|Healthy|Low-grade Inflammation|Normal Weight Adults|Risk Factor, Cardiovascular|Hypertension|Hypercholesterolemia|Abdominal Obesity|Metabolically Healthy Controls
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intratumoral Injection of Autologous CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Talimogene Laherparepvec (T-VEC)
Status: UNKNOWN
Conditions: Melanoma
Interventions: OTHER: CD1c (BDCA-1)+ myDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-management EdUcation and SuPport to Promote PsychOsocial Health Among StRoke Survivors and Informal Caregivers in a VirTual Stroke Community (SUPPORT)
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Learning in a Virtual Environment (LIVE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Thoracic Epidural Versus Serratus Anterior Plane Block Versus Erector Spinae Plane Block on Incidence of PTPS
Status: UNKNOWN
Conditions: Post-thoracotomy Pain Syndrome|Erector Spinae Plane Block|Serratus Anterior Plane Block
Interventions: PROCEDURE: Thoracic epidural infusion|DEVICE: Erector Spinae Plane Block|DEVICE: Serratus Anterior Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OsteoGen Plug vs. Freeze-dried Bone Allograft With Collagen Barrier
Status: RECRUITING
Conditions: Nonterminal Premolar Needing Extraction
Interventions: DEVICE: OsteoGen Plug|DEVICE: BioGide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lipophilic Versus Hydrophilic Statins on Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Atorvastatin|DRUG: Rosuvastatin|OTHER: guideline directed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation for Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression
Interventions: DRUG: Vitamin D3, Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eccentric Cycling Exercise on Hemodynamic and Hemorheologic Properties
Status: UNKNOWN
Conditions: Eccentric Exercise Training
Interventions: BEHAVIORAL: Eccentric cycling training|BEHAVIORAL: Concentric cycling training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Approved Drug in Patients With Asthma (0476-289)(COMPLETED)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0476, montelukast sodium / Duration of Treatment: 4 weeks|DRUG: Comparator: placebo / Duration of Treatment: 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotenoid Response to the Intake of Vegetables and Fruits
Status: COMPLETED
Conditions: Resonance Raman Spectroscopy for Dietary Carotenoid Intake
Interventions: OTHER: Carotenoid Depletion|OTHER: Carotenoid Repletion|OTHER: Carotenoid Depletion|OTHER: Natural Repletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Height Loss, Kyphosis Indicators, Bone Mineral Density and Vertebral Fractures in Chinese Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis Fracture
Interventions: RADIATION: dual energy X-ray absorptiometry|RADIATION: lateral spine imaging from T4 to L4 on X-ray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Validation of the LumiraDx SARS-CoV-2 & Flu A/B Test in Detecting and Differentiating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza A (Flu A), and/or Influenza B (Flu B)
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2|Influenza A|Influenza B|Asymptomatic COVID-19
Interventions: DIAGNOSTIC_TEST: LumiraDx SARS-CoV-2 & Flu A/B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Results of the Aortic Valve Reconstruction in Children
Status: RECRUITING
Conditions: Aortic Valve Insufficiency
Interventions: DIAGNOSTIC_TEST: Physical examination|DIAGNOSTIC_TEST: The Ross Classification for Heart Failure in Children|DIAGNOSTIC_TEST: The Aristotle score|OTHER: Assessment of administered specific therapy|DIAGNOSTIC_TEST: Multispiral computed tomography/3D echocardiography|DIAGNOSTIC_TEST: Transthoracic and transesophageal echocardiography|DIAGNOSTIC_TEST: 12-lead electrocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolitinib|DRUG: Best Available Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity
Status: UNKNOWN
Conditions: Hypersensitivity Dentin|Dentin Sensitivity|Dentin Hypersensitivity|Dentine Hypersensitivity
Interventions: DRUG: UltraEZ|DRUG: Enamelast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TRC101 in Subjects With Metabolic Acidosis Associated With Chronic Kidney Disease
Status: COMPLETED
Conditions: Metabolic Acidosis
Interventions: DRUG: TRC101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Pharmacokinetic of Switching From Cangrelor to Prasugrel in ACS Patients Undergoing PCI
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DRUG: Cangrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular and Molecular Biomarkers in Patients With Lichen Planus
Status: RECRUITING
Conditions: Lichen Planus
Interventions: OTHER: Blood samples collection|OTHER: Skin or mucous membrane brushing|OTHER: Skin or mucous membrane biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing Binimetinib as a Potential Targeted Treatment in Cancers With NRAS Genetic Changes (MATCH-Subprotocol Z1A)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMS as a Treatment for Apathy in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Apathy in Dementia
Interventions: DEVICE: Intermittent Theta Burst Stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: Technosphere® Insulin Inhalation Powder|DRUG: 70% insulin aspart protamine suspension and 30% insulin aspart injection (rDNA origin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress Test
Status: NOT_YET_RECRUITING
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: DRUG: Pre and post-CPB Drug: Dobutamine Hydrochloride|DRUG: Post-CPB Drug: Dobutamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of FFP104 in Subjects With Crohn's Disease
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: DRUG: FFP104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trends Over Time (1990-2010) of Diarrhoea-related Incidence, Hospitalizations and Deaths in Children of Panama
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: OTHER: Epidemiologic Surveillance System of the Ministry of Health of Panama|OTHER: Mortality database of the Contraloria General de la Republica|OTHER: Hospital discharge records
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Trial Comparing the Cost of Post Operative X-rays for Fractures Treated With Stable Internal Fixation
Status: COMPLETED
Conditions: Simplified Postoperative Radiographs
Interventions: OTHER: No-Xray|OTHER: Xray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pramipexole Extended Release Versus Pramipexole Immediate Release for 18 Weeks in Chinese Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: pramipexole immediate release tablet|DRUG: pramipexole extended release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Octreotide Acetate in Microspheres 20 mg|DRUG: Octreotide Acetate in Microspheres|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Follow-up in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Treatment Compliance
Interventions: DEVICE: Mobile application MyDignio (follow disease activity by assigning questionnaires to participants)|OTHER: Conventional prescheduled follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Speed of Action of a Product to Control Gastric Hydration and Gastroesophageal Reflux
Status: RECRUITING
Conditions: Oesophageal Reflux|Gastric Reflux|Hyperactivity; Stomach
Interventions: DEVICE: Antacid|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of a New LY900014 Formulation in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY900014|DRUG: Insulin Lispro (Humalog)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: DisCoVisc|DEVICE: DuoVisc|DEVICE: Healon5|DEVICE: Amvisc Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protein Intake and Satiety: a Postprandial Study
Status: COMPLETED
Conditions: Satiety
Interventions: DIETARY_SUPPLEMENT: Experimental dietary protein|DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study on the Health Impact of Air Filters in Chinese Adults
Status: COMPLETED
Conditions: Inflammation|Coagulation|Blood Pressure|Pulmonary Function
Interventions: BEHAVIORAL: Air purifiers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of SHR1701 Combined With Radiotherapy for Metastatic Non-small Cell Lung Cancer Failure After First-line Treatment
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: SHR1701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Real-Time Guidance System in Home Care of Patients With PICC or PORT
Status: RECRUITING
Conditions: Gastrointestinal Neoplasms
Interventions: OTHER: Real-Time Guidance of Home Care for Patients with PICC or PORT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT