pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 2
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Benlysta|DRUG: Candin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety Study to Assess a DNA Vaccine Administered by Particle Mediated Delivery to the Skin in Healthy Subjects
Status: COMPLETED
Conditions: HSV-2
Interventions: BIOLOGICAL: pPJV7630 with pPJV2012 administered by PMED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Depomedrol for Genicular Nerve Block.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Methylprednisolone Injection|DRUG: Bupivacaine Hcl 0.5% Inj_#2|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serotonin 1A Agonists and Cognition in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: adjunctive treatment with buspirone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Levosimendan During Mitral Valve Surgery
Status: COMPLETED
Conditions: Mitral Valve Stenosis With Incompetence or Regurgitation
Interventions: DRUG: Levosimendan|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
Status: RECRUITING
Conditions: Post-Concussion Syndrome|COVID Long-Haul|COVID-19
Interventions: DEVICE: percutaneous electrical nerve-field stimulation, PENFS|DEVICE: percutaneous electrical nerve-field stimulation, PENFS (sham device)|DEVICE: percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
Status: RECRUITING
Conditions: HLH - Hypoplastic Left Heart Syndrome|DORV|DILV - Double Inlet Left Ventricle|Mitral Atresia|Tricuspid Atresia|Unbalanced AV Canal|Single-ventricle|Heart Defects, Congenital|Cardiovascular Abnormalities|Cardiovascular Diseases|Heart Diseases
Interventions: COMBINATION_PRODUCT: Tissue Engineered Vascular Grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Barrier Dressing Versus Closed-incision Negative Pressure Therapy in the Obese Primary Total Joint Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: COMBINATION_PRODUCT: Antimicrobial Barrier Dressing|DEVICE: Negative Pressure Wound Therapy (NPWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine
Status: UNKNOWN
Conditions: Polio
Interventions: BIOLOGICAL: IPV|BIOLOGICAL: bOPV|BIOLOGICAL: mOPV type 2|BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of Ketoconazole Mediated CYP3A4 Inhibition on Pharmacokinetics of Tamsulosin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tamsulosin HCl|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone/metformin hydrochloride
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transdermal Contraceptive Patch - Endometrial Effects Study
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Ethinylestradiol/Gestogene (BAY86-5016)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure
Status: NOT_YET_RECRUITING
Conditions: Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset|TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2|MCP-2: Monocyte Chemo-attractant Protein-2
Interventions: OTHER: Measuring inflammatory serum biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gait and Balance Parameters Before and After Parathyroidectomy in Patients With Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Primary Hyperparathyroidism
Interventions: DIAGNOSTIC_TEST: gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: NightBalance Sleep Position Trainer (SPT)|DEVICE: Automated Adjusting Positive Airway Pressure (APAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
Status: RECRUITING
Conditions: Cervical Carcinoma|Endometrial Carcinoma|Endometriosis|Pelvic Inflammatory Disease
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Strength Training in Heart Transplant Recipients
Status: RECRUITING
Conditions: Dysphagia|Heart Transplant Recipients
Interventions: BEHAVIORAL: Active respiratory muscle strength training|BEHAVIORAL: Sham respiratory muscle strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Efficacy and Safety of IV/PO Moxifloxacin in the Treatment of cSSSIs
Status: COMPLETED
Conditions: Infectious Diseases
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Amoxicilline/clavulanic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Preliminary Efficacy of EDTA Eye Drops on Band Keratopathy
Status: COMPLETED
Conditions: Corneal Dystrophy, Band-Shaped
Interventions: DRUG: EDTA Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate an Osteogenic Protein 1 (OP-1) Putty Spinal System and an Autograft Spinal System
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: TLIF with a PEEK Spacer System and XIA Spinal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Walking Program and Inspiratory Muscle Training in Individuals With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III
Interventions: BEHAVIORAL: High-intensity IMT plus walking|BEHAVIORAL: Low-intensity IMT plus walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Cmv Congenital|CMV|Congenital Cmv|SNHL|Sensorineural Hearing Loss
Interventions: DRUG: Valganciclovir|DRUG: Simple Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules
Status: COMPLETED
Conditions: Current Smoker|Former Smoker|Multiple Pulmonary Nodules|Tobacco Use Disorder
Interventions: DRUG: Aspirin|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: JS004 Combined With Toripalimab and With Standard Chemotherapy Treat Patients With Advanced Lung Cancer
Status: RECRUITING
Conditions: Advanced Lung Cancer
Interventions: BIOLOGICAL: Recombinant humanized anti-BTLA monoclonal antibody (JS004) injection|BIOLOGICAL: Toripalimab|DRUG: Docetaxel|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Continuous Glucose Monitoring System Among Cardiac Surgery Patients
Status: RECRUITING
Conditions: Cardiac Disease|PreDiabetes|Diabetes Mellitus
Interventions: DEVICE: Dexcom G6|DEVICE: SMBG or venous/arterial blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Moderate Hepatic Impairment on the Pharmacokinetics and Metabolism of a Single Dose of Licarbazepine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Licarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Unsaturated Fatty Acid Improves Cognitive Function in Patients With Depression
Status: UNKNOWN
Conditions: Cognitive Impairment|Depression
Interventions: DIETARY_SUPPLEMENT: Experimental group of n-pufas improving cognitive formula|DIETARY_SUPPLEMENT: General fish oil formula product adjuvant treatment control group|DIETARY_SUPPLEMENT: Placebo assisted treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Neurological ICU Sedation Trial (ANIST)
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Fentanyl/Dexmedetomidine|DRUG: Fentanyl/Propofol|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteral Glutamine in Neurologically-injured Patients
Status: COMPLETED
Conditions: Neurologic Injury|Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Enteral glutamine powder|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 2nd Line Gemcitabine Monotherapy for Transitional Cell Carcinoma of Urothelium (TCC) After CDDP Regimen
Status: COMPLETED
Conditions: Urologic Neoplasms|Carcinoma, Transitional Cell
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELAX: A Mobile Application Suite Targeting Obesity and Stress
Status: COMPLETED
Conditions: Stress|Weight
Interventions: BEHAVIORAL: Comprehensive Dietary Self-Monitoring; Device: smartphone; Other: physical activity|BEHAVIORAL: Simple Dietary Self-Monitoring; Device: smartphone; Other: physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Hemostasis Techniques After Transradial Coronary
Status: COMPLETED
Conditions: Coronary Artery Disease With Myocardial Infarction
Interventions: DEVICE: Standardized compressive dressing|DEVICE: Hemostasis with TerumoBand®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women
Status: WITHDRAWN
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|FIGO Stage IIB Cervix Carcinoma|FIGO Stage III Cervix Carcinoma|FIGO Stage IVA Cervix Carcinoma|HIV Infection
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Paclitaxel|PROCEDURE: Patient Monitoring|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Cough
Interventions: DRUG: ME-015 (Suplatast Tosilate)|OTHER: Identical placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Oral Care With Coconut Oil on the Degree of Oral Mucositis in Pediatric Oncology Patients
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: OTHER: coconut oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ecological Momentary Breastfeeding Intervention
Status: RECRUITING
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Regular messages|BEHAVIORAL: Nurse-led real-time support messages (chat type)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Relative Bioavailability of INS068 Injection With Two Different Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: INS068 injection|DRUG: INS068 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NICE: NeuroImaging in Cessation Education
Status: TERMINATED
Conditions: Stroke|Smoking Cessation
Interventions: BEHAVIORAL: Neuroimages of stroke|BEHAVIORAL: standardized smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bipolar Versus Monopolar Resection of Benign Prostate Hyperplasia
Status: COMPLETED
Conditions: Acute Hyponatremia
Interventions: OTHER: 5% Mannitol|OTHER: 0,9% Sodium chloride|DEVICE: monopolar resectoscope|DEVICE: bipolar resectoscope TURis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I-II Study of HM781-36B Combined With Paclitaxel and Trastuzumab in HER-2 Positive Advanced Gastric Cancer
Status: COMPLETED
Conditions: HER-2 Positive Advanced Gastric Cancer
Interventions: DRUG: HM781-36B(Poziotinib)|DRUG: Paclitaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Of Imtox-25 In Adults With Refractory/Relapsed Cd25 Positive Adult T Cell Leukemia/Lymphoma
Status: TERMINATED
Conditions: Adult T Cell Leukemia|Adult T Cell Lymphoma
Interventions: DRUG: IMTOX-25
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Septal Defect - Exercise Capacity and Pulmonary Hypertension
Status: COMPLETED
Conditions: Atrial Septal Defect|Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Right side catheterization|DIAGNOSTIC_TEST: Exercise test|DIAGNOSTIC_TEST: Holter monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety of Individualized Combination Therapy With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C (MASTER)
Status: WITHDRAWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]|DRUG: ribavirin [Copegus]|DRUG: ribavirin [Copegus]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization Versus Medical Treatment in Symptomatic Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Embosphere® (Prostatic Arteries Embolization)|DRUG: Drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iChoose Decision Kidney Aid for End-Stage Renal Disease Patients
Status: COMPLETED
Conditions: End-Stage Kidney Disease|Kidney Failure, Chronic|Kidney Transplantation
Interventions: BEHAVIORAL: iChoose Kidney Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota Transplant Therapy for Pulmonary Arterial Hypertension: Early Safety and Feasibility Study
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Intestinal microbiota transplant (IMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Clofarabine in Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Guselkumab|BIOLOGICAL: Golimumab|BIOLOGICAL: JNJ-78934804|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Cyclo-Z in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Cyclo-Z|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole IM Depot in the Acute Treatment of Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot|DRUG: Aripiprazole tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathobiology and Reversibility of Prediabetes in a Biracial Cohort
Status: COMPLETED
Conditions: Prediabetes|Type 2 Diabetes|Obesity
Interventions: BEHAVIORAL: Intensive Lifestyle Intervention (ILI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Resistance Venous Blood Flow Restriction Training (LR-VBFRT) on Biceps Brachii Muscle Performance
Status: COMPLETED
Conditions: Muscle Weakness Condition
Interventions: OTHER: Low Resistance training with venous blood flow restriction|OTHER: High Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Vedolizumab in Patients With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: vedolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nucleoside Analogue Prevent Vertical Transmission of Hepatitis B Virus
Status: COMPLETED
Conditions: Hepatitis B Infection|Chronic Infection|Viremia
Interventions: DRUG: Telbivudine|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hospitalization at Home of Elderly Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Treatment of elderly patients in a GMW|OTHER: Treatment of elderly patients in GHHS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Venetoclax in Combination With Rituximab in Waldenström's Macroglobulinemia
Status: NOT_YET_RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Venetoclax; Rituximab|DRUG: DRC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavonoids, Exercise, Gut-Derived Phenolics
Status: COMPLETED
Conditions: Exercise and Gut-derived Phenolics
Interventions: DIETARY_SUPPLEMENT: Flavonoid supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Obesity
Interventions: BEHAVIORAL: PEDALL|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma
Status: UNKNOWN
Conditions: Glioma
Interventions: DRUG: 68Ga-BNOTA-PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Laparoscopic Cholecystectomy|Postoperative Nausea and Vomiting
Interventions: DRUG: normal Saline|DRUG: Dexamethasone|DRUG: Dexmedetomidine|DRUG: Combination of dexamethasone + dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Warfarin After the First Trimester in Pregnant Women With APS
Status: RECRUITING
Conditions: Recurrent Miscarriage|Antiphospholipid Syndrome
Interventions: DRUG: Enoxaparin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Optimization of Rosuvastatin in Early Stage and Metastatic Estrogen Receptor Positive Breast Cancer Patients on Endocrine Therapy
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins
Status: UNKNOWN
Conditions: Aortic Stenosis|Arteriosclerosis|Familial Hypercholesterolemia|Conventional Transthoracic Echocardiogram
Interventions: PROCEDURE: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracoronary Darbepoetin-alpha to Reduce The Infarct Size and Post-Infarct Remodeling
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Darbepoetin alfa|DRUG: Control Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients
Status: COMPLETED
Conditions: Acute Kidney Injury|Acute Renal Failure
Interventions: PROCEDURE: Dialysis|PROCEDURE: Standard SLED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia B|Mucopolysaccharidosis I|Mucopolysaccharidosis II
Interventions: BIOLOGICAL: SB-318|BIOLOGICAL: SB-913|BIOLOGICAL: SB-FIX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Do We Need Computer Assistance To Improve the Survival of Primary Total Knee Arthroplasty. A Minimum Ten Years Follow-up
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Non-Computer Assistance TKA|PROCEDURE: Computer Assistance TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow up of Clinical Outcome of Deferred vs Immediate Stenting in High Thrombus Stemi Patients
Status: NOT_YET_RECRUITING
Conditions: STEMI
Interventions: DEVICE: PPCI in heavy thrombus burden STEMI patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Home Versus Office Biofeedback for Constipation
Status: COMPLETED
Conditions: Constipation|Dyssynergia
Interventions: DEVICE: Home Biofeedback Therapy|OTHER: Office Biofeedback Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Action Observation and Repetitive Task Practice on Upper Extremity Outcomes in Chronic Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: BEHAVIORAL: Action Observation + Repetitive Task Practice|BEHAVIORAL: Placebo Video + Repetitive Task Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genes as Predictors of Response to Gemcitabine, Docetaxel, and Capecitabine (GTX) in Metastatic or Unresectable Pancreatic Cancer.
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine, gemcitabine, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Radiotherapy in Head and Neck Tumor Patients
Status: RECRUITING
Conditions: Head and Neck Neoplasms|Head and Neck Cancer|Adaptive Radiotherapy|Optimization
Interventions: RADIATION: Adaptive Radiotherapy|RADIATION: image guided radiotherapy without online adaptation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 CAR T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and NHL
Status: ACTIVE_NOT_RECRUITING
Conditions: CD19-ALL|CD19-LNH
Interventions: BIOLOGICAL: CD19-CAR T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Midazolam on White-coat Hypertensive Dental Patients
Status: COMPLETED
Conditions: Transient Hypertension
Interventions: DRUG: Midazolam|DRUG: Normal Saline Solution (NSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 5 and 7-year Follow-up of the YOMEGA Trial Cohort
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: Laparoscopic Mini-gastric bypass|PROCEDURE: Laparoscopic Roux-en-Y Gastric ByPass (RYGBP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Artificial Pancreas Therapy in Preschoolers, Age 2-6
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Tandem t:slim X2 with Control-IQ Technology + Dexcom G6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Ligasure® to Destroy Cornual Portion of Fallopian Tube
Status: COMPLETED
Conditions: Recruiting|Completed
Interventions: DEVICE: The Effect of Ligasure® to Destroy Cornual Portion of Fallopian Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Study of Salvage XRT + ADT +/- Abiraterone and Apalutamide for Rising PSA After RP (FORMULA-509)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: GnRH|DRUG: Bicalutamide|RADIATION: Salvage radiation|DRUG: Abiraterone|DRUG: Prednisone|DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-court Trial of NBP to Prevent Substance Abuse and Mental Health Disorders (MTC)
Status: COMPLETED
Conditions: Divorce|Drug Abuse|Mental Health Disorder
Interventions: BEHAVIORAL: New Beginnings Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Measles Vaccine, Varicella Vaccine and Hepatitis-A Vaccine
Status: UNKNOWN
Conditions: Measles|Varicella|Hepatitis A
Interventions: BIOLOGICAL: Measles vaccine|BIOLOGICAL: Hepatitis-A vaccine|BIOLOGICAL: Varicella vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reduction in Clinical Variance Using Targeted Design Changes in Computerized Provider Order Entry Order (CPOE) Sets
Status: COMPLETED
Conditions: Asthma Exacerbation
Interventions: OTHER: Evidence Based Intervention to order set
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Self Titration With Apidra to Reach Target Study (START)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine|DRUG: Apidra (insulin glulisine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MET-3 and MET-5 on Gut Microbiome and Metabolic Function in Men and Women With Hypertriglyceridemia
Status: UNKNOWN
Conditions: Obesity, Metabolically Benign
Interventions: BIOLOGICAL: MET-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jaw Kinematics and Muscle Activation in Patients With Non-specific Chronic Neck Pain
Status: COMPLETED
Conditions: Temporomandibular Disorder|Nonspecific Chronic Neck Pain|Biomechanical Phenomena
Interventions: OTHER: Cervical range of motion (CROM)|OTHER: Pressure pain threshold (PPT)|OTHER: Cranial-cervical angle (CCA)|OTHER: Jaw kinematics|OTHER: Muscle activation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Simple Transanal Local Excision，Transanal Local Excision Following Radiotherapy Versus Total Mesorectum Excision for the Treatment of the Ultra-low T2N0M0 Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: transanal local excision following radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine vs Standard Penile Block for Hypospadias Repair
Status: WITHDRAWN
Conditions: Hypospadias
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Addition of Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation to an Education and Exercise Program in Subjects With Chronic Pain Due to Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Chronic Pain
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|DEVICE: TENS|BEHAVIORAL: Exercise and General Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Propofol Versus Midazolam With Fentanyl for EGD Endomicroscopy
Status: COMPLETED
Conditions: Gastritis|Functional Dyspepsia
Interventions: DRUG: propofol|DRUG: midazolam with fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease
Status: SUSPENDED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: vadadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia and High-risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Decitabine|DRUG: Gemtuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)
Status: COMPLETED
Conditions: Mycoses
Interventions: DRUG: Posaconazole oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit
Status: WITHDRAWN
Conditions: Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: beta-hydroxy-beta-methylbutyrate|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vital HP®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Ranging Study to Evaluate Safety and Efficacy of Bromfenac Ophthalmic Solution in Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Bromfenac Ophthalmic Solution A|DRUG: Bromfenac Ophthalmic Solution B|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics and Pharmacodynamics Study Under Fasting and Fed Conditions With Paliperidone Extended-release and Immediate-release Formulations
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Cephalexin Suspension 250
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: Cephalexin 125 mg/5ml|DRUG: Cephalexin 250mg/5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation
Status: RECRUITING
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Ofatumumab|DRUG: Disease modifying treatment (DMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ocrelizumab in Participants With Follicular Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Pharmacokinetics, and Anti-Viral Activity of VRC01 and VRC01LS in the Serum and Mucosa of Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC01|BIOLOGICAL: VRC01LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of a Supportive Mobile Health for Life Style Modification on Blood Pressure and Insulin Resistance Improvement in People With Metabolic Abnormalities
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Mobile application for self monitoring|OTHER: Education|OTHER: Mobile application for personal coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections|Hepatitis B|Measles|Pneumococcal Infections|Pertussis
Interventions: BIOLOGICAL: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed|BIOLOGICAL: Measles-Mumps-Rubella Vaccine (Live)|BIOLOGICAL: Pneumococcal Vaccine, Polyvalent (23-valent)|BIOLOGICAL: Pneumococcal Conjugate Vaccine, Heptavalent|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Eradication Rate
Interventions: DRUG: Modified non-clarithromycin triple therapy|DRUG: Sequential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histiocytosis in Injecting Drug Users
Status: ENROLLING_BY_INVITATION
Conditions: Histiocytosis
Interventions: DIAGNOSTIC_TEST: Chitotriosidase|DIAGNOSTIC_TEST: Mass spectrometry|DIAGNOSTIC_TEST: X-ray spectromicroscopy|DIAGNOSTIC_TEST: Fluorescence microscopy|DIAGNOSTIC_TEST: Transcriptomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postmarketing Study of ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) in Relation to Venous Thromboembolism (Blood Clots), Stroke and Heart Attacks
Status: COMPLETED
Conditions: Contraception|Female Contraception
Interventions: DRUG: Monophasic or triphasic Oral contraceptive tablet|DRUG: Ortho Evra transdermal patch containing 6 mg NGMN/0.75 mg EE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalised Against Standard High Tibial Osteotomy
Status: RECRUITING
Conditions: Medial Knee Osteoarthritis
Interventions: DEVICE: TOKA|DEVICE: Tomofix or ActivMotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
Status: COMPLETED
Conditions: Chronic Kidney Disease|Iron Deficiency|Anemia
Interventions: DRUG: ferric citrate|DRUG: ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines
Status: RECRUITING
Conditions: Chronic Inducible Urticaria
Interventions: DRUG: Briquilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest
Status: TERMINATED
Conditions: Cardiac Arrest Due to Underlying Cardiac Condition|Ventricular Fibrillation|Cardiopulmonary Arrest With Successful Resuscitation
Interventions: PROCEDURE: Initial CCL admission|DIAGNOSTIC_TEST: Initial ICU admission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: brivanib alaninate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery and Reducing Ionizing Radiation of the Unknown Primary
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Intensity Modulated Radiotherapy (IMRT) to Mucosa at Risk|PROCEDURE: Surgical Intervention|RADIATION: Intensity Modulated Radiotherapy (IMRT) to Ipsilateral Neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Tolerance, Safety and Pharmacokinetics of Germinal Peptide Eye Drops in Healthy Volunteers
Status: COMPLETED
Conditions: Corneal Defect
Interventions: DRUG: Germinal peptide eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Alberta Vascular Risk Reduction Community Pharmacy Project: RxEACH
Status: COMPLETED
Conditions: Diabetes|Chronic Kidney Disease|Established Atherosclerotic Vascular Disease|Framingham Risk Score More Than 20 Percent
Interventions: OTHER: Advanced Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Added-value of SPECT/CT in Patients Undergoing LM/SL for Gynecological Cancers
Status: COMPLETED
Conditions: Cervical Cancer|Vulvar Cancer
Interventions: DEVICE: SPECT/CT guided LM/SL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SB-480848 in Major Adverse Cardiovascular Events - Integrated Summary of Efficacy and Safety From the STABILITY Trial (LPL100601) and the SOLID-TIMI-52 Trial (SB-480848/033)
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: darapladib|DRUG: placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Forced Versus Spray Coagulation in Women Undergoing LLETZ-conization for Cervical Dysplasia: a Randomized Trial
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: PROCEDURE: Spray|PROCEDURE: Forced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate SLN360 in Participants With Elevated Lipoprotein(a) at High Risk of Atherosclerotic Cardiovascular Disease Events
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atherosclerosis|Lipoprotein(a)
Interventions: DRUG: SLN360|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-121 Lotion|DRUG: IDP-121 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Insomnia
Interventions: BEHAVIORAL: Telehealth cognitive behavioral therapy for insomnia (tCBT-I)|BEHAVIORAL: Web-based cognitive behavioral therapy for insomnia (wCBT-I)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Establish a Novel Prototype of Clinical Pharmacy Services by Warfarin Consultation in a Pharmacist Clinic
Status: UNKNOWN
Conditions: Intentional Warfarin Sodium Overdose
Interventions: OTHER: patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH