pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Determining the Clinical Utility of Using Virtual Reality Headsets to Assess Visual Function in Those With Glaucoma.
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DEVICE: Visual field testing using Oculus Rift and Humphrey Visual Field Perimeter|DEVICE: Visual Field Testing using HUmphrey 24-3 Perimeter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effects of Static and PNF Hamstring Stretching Exercises in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Static Stretching|OTHER: PNF Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Blasts More Than 20 Percent of Bone Marrow Nucleated Cells|Blasts More Than 20 Percent of Peripheral Blood White Cells|Myelodysplastic/Myeloproliferative Neoplasm|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery
Status: RECRUITING
Conditions: Lower Abdominal Surgery
Interventions: DRUG: Bupivacaine Hydrochloride|DEVICE: Ultrasound device|DRUG: Dexamethasone|DEVICE: echogenic needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: University of Virginia Natural History Study
Status: ENROLLING_BY_INVITATION
Conditions: Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Sarcoidosis|Connective Tissue Diseases|Hypersensitivity Pneumonitis|Idiopathic Interstitial Pneumonias
Interventions: OTHER: Interstitial Lung Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FLUENCY® PLUS Endovascular Stent Graft for In-stent Restenosis
Status: COMPLETED
Conditions: Restenosis
Interventions: DEVICE: Fluency Plus Endovascular Stent Graft|DEVICE: Percutaneous Transluminal Angioplasty only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: TNBC|Brain Metastasis
Interventions: DRUG: SHR-A1921 + Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Applied During Chemotherapy on Anxiety, Nausea and Satisfaction Levels
Status: COMPLETED
Conditions: Anxiety|Chemotherapy Effect|Satisfaction, Patient|Cancer|Nursing Caries
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Zactima™ in Patients With Castration-refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ZD6474 (Vandetanib)|DRUG: Bicalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Modulation of Perioperative Blood Glucose and Related Hormones
Status: COMPLETED
Conditions: Dexmedetomidine|Blood Glucose
Interventions: DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Darifenacin in Patients Suffering From Multiple Sclerosis and Neurogenic Detrusor Overactivity
Status: TERMINATED
Conditions: Multiple Sclerosis|Overactive Detrusor
Interventions: DRUG: Darifenacin (BAY79-4998)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Early Laparoscopic Enterolysis Versus Nonoperative Management for High-grade SBO
Status: TERMINATED
Conditions: Small Bowel Obstruction
Interventions: PROCEDURE: Early laparoscopic enterolysis|PROCEDURE: nonoperative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exam Indicated Cerclage in Singleton Gestation 24 Weeks to 25 Weeks and 6 Days Gestation
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: PROCEDURE: Physical Exam Indicated Cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Of The Efficiencies Of Peloid and Paraffine Treatments In Patients With Hallux Rigidus
Status: COMPLETED
Conditions: Hallux Rigidus
Interventions: OTHER: Peloid treatment|OTHER: Paraffin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tocilizumab as an add-on Therapy to Corticoids in Giant Cell Arteritis: Proof of Concept Study.
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: corticoids+ tocilizumab 8mg/Kg/4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Erythromycin and Rivaroxaban in Study Participants With Normal and Reduced Kidney Function
Status: COMPLETED
Conditions: Healthy|Renal Insufficiency
Interventions: DRUG: Rivaroxaban (normal renal function)|DRUG: Rivaroxaban (mild and moderate renal impairment)|DRUG: Erythromycin (normal renal function)|DRUG: Erythromycin (mild and moderate renal function)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inverted ILM-flap Techniques Variants for Macular Hole Surgery: Outcomes Comparison
Status: UNKNOWN
Conditions: Macular Holes
Interventions: PROCEDURE: Cover Group|PROCEDURE: Fill Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Parkinson Disease
Interventions: BEHAVIORAL: Phonetic complexity effects on speech motor performance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the Treatment of Small Volume Recurrent Ovarian Carcinoma Limited to the Peritoneal Cavity
Status: WITHDRAWN
Conditions: Recurrent Ovarian Carcinoma
Interventions: DRUG: Cisplatin|RADIATION: Whole Abdomen Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Prednisone|DRUG: Immunosuppressive regime (azathioprine, mycophenolate mofetil or methotrexate)|DRUG: Methylprednisolone|DRUG: Ocrelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dr. Reddy's Divalproex Sodium Capsules (Sprinkle), 125 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Divalproex Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Motivational Interviewing (GMI) For Homeless Veterans In VA Services
Status: COMPLETED
Conditions: Alcoholism|Substance-related Disorders|Dual Diagnosis
Interventions: BEHAVIORAL: Group Motivational Interviewing (GMI)|BEHAVIORAL: Control Treatment Condition (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Signatures of Cognitive Disorders Related to Intensive Care Unit (ICU) delirium_ BRAINSTORM-EEG
Status: NOT_YET_RECRUITING
Conditions: Cognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: mEEG battery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects
Status: COMPLETED
Conditions: Asthma|Heart Rate Fast
Interventions: DRUG: salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome
Status: COMPLETED
Conditions: MELAS Syndrome
Interventions: DIETARY_SUPPLEMENT: Glutamine oral supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Placebo|DRUG: dalcetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiopaque Matrix MK-8591 Implant in Participants at Low-Risk for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591-043)
Status: WITHDRAWN
Conditions: Human Immunodeficiency Virus|HIV
Interventions: DRUG: Islatravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hydrodilatation Versus Arthroscopic Capsular Release for Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: PROCEDURE: arthroscopic capsular release|PROCEDURE: Hydro-dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon - α2b With SARSCoV- 2 (COVID-19)
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Pegylated Interferon-α2b|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia
Status: COMPLETED
Conditions: Staph Aureus Methicillin Resistant Bacteremia
Interventions: DRUG: Fosfomycin 2gr/6h iv|DRUG: Daptomycin 10mg/kg/24h iv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERCP Mechanical Simulator (EMS) Practice for Training Endoscopic Sphincterotomy
Status: UNKNOWN
Conditions: Endoscopic Sphincterotomy
Interventions: OTHER: Simulation and lecture|OTHER: Lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of the Influenza Vaccine (Split Virion, Inactivated) Northern Hemisphere 2009-2010 Formulation (Intradermal Route)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza virus vaccine 2009-2010 formulation|BIOLOGICAL: Influenza virus vaccine 2009-2010 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)
Status: RECRUITING
Conditions: Cervix Cancer|Cervical Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Immune Thrombocytopenic Purpura (ITP) With Intravenous Immunoglobulin IgPro10
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: BIOLOGICAL: Immunoglobulin Intravenous (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Treatment Effect in Patients With FBSS Using an Electronic Nose: a Pilot Study
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: SCS is switched off|DEVICE: SCS is switched on
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
Status: RECRUITING
Conditions: Angle-closure Glaucoma|Minimally Invasive Glaucoma Surgery|Goniosynechialysis|Goniotomy|Glaucoma
Interventions: PROCEDURE: various types of angle interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metagenomics and Integrative Systems Medicine of Cardiometabolic Diseases
Status: UNKNOWN
Conditions: Cardiometabolic Disease
Interventions: OTHER: Adipose tissue biopsies (omental and subcutaneous) liver|RADIATION: CT-scan|OTHER: Stools sampling|OTHER: DNA sampling|OTHER: Blood sampling|OTHER: Urine sampling|RADIATION: Dual energy X-ray absorptiometry-scan (DEXA-scan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Repurposed Drugs in Research for Cancer Clinical Trials- Pitavastatin
Status: COMPLETED
Conditions: Glioblastoma Multiforme, Adult|Recurrent Glioblastoma
Interventions: DRUG: Pitavastatin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in Children
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Fosmidomycin and Clindamycin co-administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Intravascular Volume Using USG of IVC Diameter Compared to VPW Chest X-ray
Status: COMPLETED
Conditions: Unintubated Patients in ICU and Resuscitation Room
Interventions: DIAGNOSTIC_TEST: Inferior vena cava (IVC) diameter using USG|DIAGNOSTIC_TEST: Vascular pedicle width (VPW)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexmedetomidine and Postoperative Cognitive Dysfunction (POCD)
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction|Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Repeated Low-Level Red-Light Therapy in Myopia Control
Status: UNKNOWN
Conditions: Myopia|Refractive Errors|Eye Diseases
Interventions: DEVICE: Low-level Red-light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Tablet Containing Two FDA-Approved Drugs In HIV-Infected Patients Who Have Not Received Prior Therapy
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: efavirenz|DRUG: tenofovir|DRUG: abacavir/lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Atorvastatin Dose Dependent Reduction of Proteinuria
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eggs for Gut Health
Status: RECRUITING
Conditions: Moderate Acute Malnutrition|Stunting|Environmental Enteric Dysfunction|Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Whole egg powder|DIETARY_SUPPLEMENT: Corn powder|DIETARY_SUPPLEMENT: Supercereal Plus|DIETARY_SUPPLEMENT: Micronutrient sprinkles|DRUG: Sulfadoxine pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery
Status: COMPLETED
Conditions: Caloric Restriction|Exercise
Interventions: DRUG: Sesame Oil|DRUG: testosterone enanthate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of SHR-A1811 Combined With Capecitabine in Treatment of Unresectable or Metastatic Breast Cancer With Low HER2 Expression.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SHR-A1811 for injection ; capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Telephone Engagement|BEHAVIORAL: Portal Engagement|BEHAVIORAL: MI-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Group Risk Reduction Intervention Therapy (GRRIT) Project
Status: RECRUITING
Conditions: Suicidal Ideation|Suicide, Attempted|Coping Skills|Depression|Anxiety|PTSD
Interventions: BEHAVIORAL: Group Brief Cognitive-Behavioral Therapy (G-BCBT)|BEHAVIORAL: Dialectical Behavior Therapy (DBT) Skills Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in Postoperative Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: OTHER: Fecal Microbiota Transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.
Status: NOT_YET_RECRUITING
Conditions: Tibial Fractures|Surgery|Complication,Postoperative
Interventions: DIAGNOSTIC_TEST: C-Arm Rotational View (CARV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Cacao FLAvonoids in LOng Covid Patients (FLALOC)
Status: RECRUITING
Conditions: Long Covid19|Fatigue Syndrome, Chronic
Interventions: DIETARY_SUPPLEMENT: Flavonoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Daratumumab|DRUG: Alemtuzumab|DRUG: Sirolimus|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: BBI-4000, 15%|OTHER: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases
Status: RECRUITING
Conditions: Punctate Palmoplantar Keratoderma Type 1|Pachyonychia Congenita
Interventions: DIAGNOSTIC_TEST: Serum chemistry|DIAGNOSTIC_TEST: Hematology|DIAGNOSTIC_TEST: Urinalysis|DIAGNOSTIC_TEST: Physical Examination|DIAGNOSTIC_TEST: Vital Signs|DIAGNOSTIC_TEST: ECG Test|DIAGNOSTIC_TEST: PK|DIAGNOSTIC_TEST: IGA scoring|DRUG: KM-001 1% cream 12 weeks treatment|DIAGNOSTIC_TEST: Clinician global impression of severity (CGI-S)|DIAGNOSTIC_TEST: Visual Analogue Scale (VAS)|DIAGNOSTIC_TEST: Patient global impression of change (PGI-C) scoring|DIAGNOSTIC_TEST: Patient global impression of severity (PGI-S) scoring|DIAGNOSTIC_TEST: Lesion photography|DRUG: KM-001 1% cream 16 weeks treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Status and Hidradenitis Suppurativa (Acne Inversa)
Status: COMPLETED
Conditions: Hidradenitis Suppurativa|Mediterranean Diet|Body Composition|Vitamin D Deficiency|Trimethylamine N-oxide (TMAO)
Interventions: DIETARY_SUPPLEMENT: Mediterranean Diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: paclitaxel|DRUG: Reparixin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Electronic Shared Decision-Making Support for Early Intervention
Status: COMPLETED
Conditions: Child Development Disorder|Development Delay
Interventions: BEHAVIORAL: Young Children's Participation and Environment Measure (YC-PEM) electronic patient-reported outcome (e-PRO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Neoadjuvant Osimertinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harbouring EGFR Mutations
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Proton Therapy or IMRT for the Treatment of Bladder Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma of the Bladder
Interventions: RADIATION: Proton therapy|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Factor VIIa Fusion Protein (rVIIa-FP, CSL689) for On-demand Treatment of Bleeding Episodes in Patients With Hemophilia A or B With Inhibitors
Status: TERMINATED
Conditions: Hemophilia A With Inhibitors|Hemophilia B With Inhibitors
Interventions: DRUG: CSL689|DRUG: Eptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia
Status: RECRUITING
Conditions: Hyperkalemia
Interventions: DRUG: Salbutamol|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
Status: UNKNOWN
Conditions: Cerebral Hypoxia|Postoperative Delirium
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE)
Status: UNKNOWN
Conditions: Heart Failure|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mid Range Ejection Fraction|Heart Failure With Reduced Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Transthoracic Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rationale and Design of Diabetes Management With Curcumin and Saffron (DMCS): a Randomised, Three Blind -Blind, Placebo-controlled Study
Status: NOT_YET_RECRUITING
Conditions: Women of Reproductive Age|Diabetes Mellitus
Interventions: DRUG: curcumin, saffron, Combination of saffron and curcumin and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of BAT Versus Mixed Physical Activity as add-on Treatment for Traumatised Refugees.
Status: COMPLETED
Conditions: PTSD|Depression|Pain
Interventions: OTHER: Control|OTHER: Basic Body Awareness Therapy|OTHER: Mixed physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma (PRP) Peri-urethral and Clitoral Injections for the Treatment of Female Orgasmic Disorder
Status: UNKNOWN
Conditions: Female Orgasmic Disorder
Interventions: BIOLOGICAL: Peri-urethral and clitoral injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
Status: COMPLETED
Conditions: Bone Cysts|Bone Atrophy|Bone Deformity|Bone Fracture|Bone Loss|Tooth Loss
Interventions: DEVICE: Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Laparoscopic Surgery for Recurrent Unilateral Endometriomas.
Status: COMPLETED
Conditions: Endometrioma|Endometriosis|Surgery
Interventions: OTHER: Anti-mullerian hormone (AMH) level dosage.|OTHER: Follicle-stimulating hormone (FSH) level dosage.|OTHER: Antral follicle count (AFC).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiofrequency Ablation Using Octopus Electrodes for Treatment of Focal Liver Malignancies
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Metastasis|Cholangiocarcinoma
Interventions: DEVICE: Separable cluster electrode (Octopus®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|High Grade B-Cell Lymphoma|Progressive Disease|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Anakinra|BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Vorinostat (MK0683), an Histone Deacetylase (HDAC) Inhibitor in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (MK-0683-095)
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Vorinostat|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Hypertonic Saline Use in the Emergency Department to Treat Acute Viral Bronchiolitis
Status: TERMINATED
Conditions: Bronchiolitis
Interventions: DRUG: Hypertonic Saline|RADIATION: Chest X-Ray|OTHER: Respiratory virus screening test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Low Dose hCG at the Time of GnRH Agonist Trigger or 35 Hours Later for the Prevention of OHSS
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: hCG|DRUG: hCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Diagnostic Value of Puncture Biopsy for PPL Under the Guidance of Navigation and Radial EBUS: a Real-World Study
Status: UNKNOWN
Conditions: Lung; Nodes
Interventions: DEVICE: Forceps biopsy combined with puncture biopsy under the guidance of Augmented Reality Navigation and Radial EBUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0004541)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal and epidermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Interventional Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Spinal Disorders
Status: COMPLETED
Conditions: Spinal Disorders
Interventions: DRUG: Oxycodone/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Biliary Reflux After Mini-gastric Bypass With Using the Biliary Reflux Index
Status: UNKNOWN
Conditions: Ulcer, Gastric|Bile Reflux
Interventions: DIAGNOSTIC_TEST: fibrogastroscopy, biopsy of the gastric mucosa, microscopy biopsy materials, using Bile Reflux Index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: This is a Randomized Study Comparing Two Doses of INT131 ( 3 mg and 1 mg) Administered Orally (PO) Daily (QD) Versus Placebo 1 Tablet PO QD in Subjects With Treatment-naïve RRMS for ≤ 3 Years
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing Remitting
Interventions: DRUG: INT131
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome in Diabetic Smokers Using Cigarettes & Combustion-Free Nicotine Delivery Systems
Status: RECRUITING
Conditions: Cardiovascular Risk Factor|Diabetes Mellitus, Type 2
Interventions: OTHER: TOBACCO CIGARETTES|OTHER: COMBUSTION-FREE NICOTINE DELIVERY SYSTEMS (C-F NDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of BIIL 284 BS on Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BIIL 284 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Coil System(Ton-bridgeMT) for Endovascular Embolization of Cranial Aneurysms
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DEVICE: Coil system(Ton-bridgeMT)|DEVICE: Axium Detachable Coil(Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Nervous System Mediation of Acute Exercise Effects on Childhood Brain and Cognition
Status: COMPLETED
Conditions: Exercise|Cognition
Interventions: OTHER: Aerobic Exercise Intervention|OTHER: Trier Social Stress Test for Children|OTHER: Seated Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: In-Office Study of the Hummingbird® in Children 6 Months-21 Years Old
Status: COMPLETED
Conditions: Ear Infection|Otitis Media
Interventions: DEVICE: Hummingbird Tympanostomy Tube System (H-TTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|BIOLOGICAL: bevacizumab|DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics
Status: COMPLETED
Conditions: Anesthesiology Devices Associated With Adverse Incidents|Intraocular Pressure
Interventions: DEVICE: Direct laryngoscope|DEVICE: C-MAC videolaryngoscope|DEVICE: McGrath videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study
Status: COMPLETED
Conditions: Invasive Candidiasis
Interventions: DRUG: Anidulafungin|DRUG: Fluconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medico Economic Study, Comparing Intrabeam® on Surgical Resection Bed to Conventional Surgery + EBRT, in Breast Cancer
Status: UNKNOWN
Conditions: Menopausal Patients|Low-risk Breast Cancer
Interventions: RADIATION: RIOP-Intrabeam® system|RADIATION: conventional surgery +RTE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Non-squamous Non-small-cell Lung Cancer|Urothelial Carcinoma|Malignant Mesothelioma
Interventions: DRUG: Cabozantinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing The Role Of Intravenous Lipid Emulsion As A Life Saving Therapy In Pesticides Toxicity
Status: UNKNOWN
Conditions: Pesticide Poisoning
Interventions: DRUG: Lipid Emulsion, Intravenous|DRUG: Atropine|DRUG: Toxogonin|DRUG: Sodium Bicarbonate Powder and ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of 2006-RD-05 on Salivary and Serum Immunoglobulin A (IgA) Levels in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 2006-RD-05|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Study of the EASYTRAK 3 Spiral Fixation Coronary Venous Bipolar Pace/Sense Lead
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: EASYTRAK 3 left ventricular pacing lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Operative Sore Throat and Dexamethasone
Status: COMPLETED
Conditions: Sore Throat|Pain
Interventions: DRUG: Placebo administration|DRUG: Dexamethasone 0.05mg/kr administration|DRUG: Dexamethasone 0.1mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Pharmacokinetic Interaction and Safety After Multiple Oral Doses of Fimasartan/Amlodipine and Rosuvastatin in Healthy Male Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Amlodipine|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study Evaluating the Efficacy and Safety of Sunitinib With or Without Bevacizumab in First-Line Patients With Metastatic Renal Cell Cancer (SABRE-R)
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: bevacizumab|DRUG: sunitinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Enhancing Immunotherapy in Advanced NSCLC：a Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer|Non-Small-Cell Lung Carcinoma
Interventions: PROCEDURE: acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History
Status: COMPLETED
Conditions: Addiction, Substance
Interventions: BEHAVIORAL: Static Approach Bias Modification|BEHAVIORAL: Adaptive Approach Bias Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Food on the Pharmacokinetics of TY-9591 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TY-9591 Tablets under Fasted Condition - Arm1|DRUG: Osimertinib Mesylate Tablets under Fasted Condition - Arm1|DRUG: TY-9591 Tablets after a High-fat Meal - Arm1|DRUG: Osimertinib Mesylate Tablets under Fasted Condition - Arm2|DRUG: TY-9591 Tablets under Fasted Condition - Arm2|DRUG: TY-9591 Tablets after a High-fat Meal - Arm2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilengitide in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: DRUG: cilengitide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Amniotic Fluid Solution in Neonates Recovering From GIT Surgeries
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: SAFE group|DRUG: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Pulmonary Sarcoidosis|Lung Function
Interventions: DRUG: levaquin; ethambutol; rifampin and azithromycin.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of a Team Approach for Discussing Prognosis and Treatment Goals in Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer|Stage 4 Breast Cancer|Recurrent Breast Cancer
Interventions: OTHER: T-PAT|OTHER: Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptability and Feasibility of a Simplified Medical Abortion Regimen in Georgia
Status: COMPLETED
Conditions: Abortion, First Trimester
Interventions: DRUG: Home administration of 200 mg mifepristone|DRUG: Home or clinic administration of 400 mcg buccal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia
Status: NOT_YET_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Ferric Derisomaltose Injection (Monoferric) and Human Erythropoietin Injection (EPIAO)|OTHER: Basic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Assessing Long-Term Safety Of Rosiglitazone In Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: Rilotumumab and Erlotinib Hydrochloride or Erlotinib Hydrochloride Alone as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and Positive Biomarker Matches
Status: TERMINATED
Conditions: MET Positive|Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rilotumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Combination of Nivolumab and Ipilimumab as a Treatment in Patients With Sarcoma of Rare Subtype
Status: RECRUITING
Conditions: Sarcoma
Interventions: DRUG: Nivolumab and IPILIMUMAB|DRUG: Pazopanib Oral Tablet [Votrient]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Response Study of E6011 in Participants With Rheumatoid Arthritis Inadequately Responding to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: E6011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability, and Immunogenicity of a Tetravalent Dengue Vaccine (V180) in Healthy Adults Who Previously Received a Live-Attenuated Tetravalent Vaccine (TV003 or TV005)
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: V180|BIOLOGICAL: Alhydrogel™|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Oral Inositol Supplementation on Obstetrics Outcomes in PCOS Women
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Inositol + Folic acid|DIETARY_SUPPLEMENT: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: semaxanib|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: pregabalin|DRUG: pregabalin/PF-00489791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Comparison of Sildenafil ODF and FCT Formulations in Healthy Korean Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SPO1101|DRUG: SPO1101D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD
Status: COMPLETED
Conditions: Alcoholism|Alcohol Dependence|Posttraumatic Stress Disorder
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT