pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Do the Health Education Materials Developed in the Gynecology and Diseases Nursing Course Affect Students' Teaching Material Motivation and Material Design Self-Efficacy Beliefs?
Status: COMPLETED
Conditions: Nursing Caries
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Transcranial Direct Current Stimulation of the Motor Cortex on Language Functions in Residual Aphasia
Status: UNKNOWN
Conditions: Residual Aphasia
Interventions: DEVICE: atDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Diaphragm Muscle Therapy on Pain and Shoulder Movement in Subjects With Rotator Cuff Injuries
Status: COMPLETED
Conditions: Rotator Cuff Injury|Diaphragm; Relaxation
Interventions: OTHER: Diaphragm manual therapy techniques|OTHER: Diaphragm mobilization through active hipopressive gymnastic exercise|OTHER: Ischemic compression techniques in shoulder myofascial trigger points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Mesothelioma; Lung
Interventions: DRUG: Bintrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The COPD CARE Study: Evaluating the Impact of a Virtual-First COPD Service on Major Cardiac and Respiratory Events
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation|COPD|Cardio/Pulm: Heart Failure
Interventions: OTHER: NuvoAir clinical service
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Performance Study of the MultiSense® Ambulatory Telemonitoring System for Non-critical Patient Management
Status: COMPLETED
Conditions: Visceral and Digestive Surgery|Post-surgical Monitoring|Post-surgical Rehabilitation
Interventions: DEVICE: MultiSense® remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
Status: COMPLETED
Conditions: Fertility Agents, Female
Interventions: DRUG: s.c. human chorionic gonadotropin (Ovitrelle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Sensitivity and Motor Block Duration of an Intravenous Dexamethasone an Axillary Block With Mepivacaine.
Status: COMPLETED
Conditions: Hand Wound|Wrist Wound|Forearm Wound|Hand Fracture|Wrist Fracture|Forearm Fracture
Interventions: DRUG: Dexamethasone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Diabetes
Interventions: DRUG: Liraglutide 6 MG/ML [Victoza]|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Yellow Pea Protein and Fibre Added to a High-carb Meal on Glycemic Response and Food Intake
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: Pasta meal with added fractions or control with no fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Defactinib|DRUG: Avutometinib|DRUG: Encorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Utility of Intergluteal Cleft as Landmark for Neuraxial Midline in Obstetrics
Status: RECRUITING
Conditions: Obstetric Anesthesia Problems
Interventions: DIAGNOSTIC_TEST: Intergluteal Cleft|DIAGNOSTIC_TEST: Neuraxial Midline|DIAGNOSTIC_TEST: Horizontal Distance between Vertical Markings
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Oral Cladribine on Remyelination and Inflammation in Multiple Sclerosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Cladribine 10 mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Severe Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile|Pseudomembranous Colitis
Interventions: BIOLOGICAL: Single-infusion FMT|DRUG: Vancomycin (before randomization)|BIOLOGICAL: multiple-infusion FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Nivolumab in Combination With Radiation Therapy as Definitive Treatment for Patients With Locally Advanced, Unresectable Head and Neck Mucosal Melanoma.
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Nivolumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischaemic preConditioning on Liver Injury in Patients Undergoing LIVER Resection Surgery
Status: UNKNOWN
Conditions: Hepatocellular Cancer
Interventions: DEVICE: Active RIC|DEVICE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)
Status: COMPLETED
Conditions: Post-operative Excessive Scarring
Interventions: DRUG: Botulinum Toxin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Efficacy of Aflibercept for the Treatment of Inflammatory CNV in Young Patients (ALINEA).
Status: COMPLETED
Conditions: Inflammatory Choroidal Neovascularization
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating Polyneuropathy
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: BIOLOGICAL: hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study Of PF-04308515 And Prednisone On Carbohydrate
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04308515|DRUG: PF-04308515|DRUG: Prednisone|DRUG: PF-04308515|DRUG: PF-04308515|DRUG: Prednisone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1
Status: COMPLETED
Conditions: Intercritical Gout
Interventions: OTHER: Placebo|DRUG: Rilonacept 80 mg|DRUG: Rilonacept 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LJPC-501 in Paediatric Patients With Hypotension Associated With Distributive or Vasodilatory Shock
Status: UNKNOWN
Conditions: Catecholamine-resistant Hypotension (CRH)|Distributive Shock|High Output Shock|Septic Shock
Interventions: DRUG: LJPC-501 (angiotensin II)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Postural Control in Lowlanders Older Than 40 Years at Altitude
Status: COMPLETED
Conditions: Altitude Hypoxia
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Degenerative Disc Disease
Interventions: BIOLOGICAL: Platelet rich plasma (PRP) with exosomes|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Lumbar Spine Disease
Interventions: DRUG: Rocuronium for deep NMB|DRUG: Rocuronium for moderate NMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion-3-DES
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: G-CSF (Dong-A pharmaceutical, Seoul, Korea)|PROCEDURE: collection of mobilized peripheral blood stem cells|PROCEDURE: Intracoronary infusion of mobilized cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients.
Status: RECRUITING
Conditions: Knee Osteoarthritis|Metformin
Interventions: DRUG: Metformin 500 Mg extended release Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monocentric Observational Study on the Diagnostic and Prognostic Role of 18F-PSMA PET (PET/CT and PET/MR) in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PET 18F-PSMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive-Behavioral Treatment and Interpretation Modification Training for Adults With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|OTHER: Interpretation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and NO in HFrEF
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Antioxidant|DIETARY_SUPPLEMENT: Tetrahydrobiopterin (BH4)|OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents
Status: COMPLETED
Conditions: Sex|Unprotected Sex|Contraception|Alcohol Use|Drug Use|Pregnancy
Interventions: BEHAVIORAL: Respecting the Circle of Life (RCL)|OTHER: Control Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Capillary Blood Volume and Pain Perception Obtained in a Process of Puncturing With Different Safety Lancets
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Acti-Lance Lite|DEVICE: Acti-Lance Universal|DEVICE: Acti-Lance Special|DEVICE: Medlance Plus Super Lite|DEVICE: Medlance Plus Lite|DEVICE: Medlance Plus Universal|DEVICE: Medlance Plus Extra|DEVICE: Medlance Plus Special|DEVICE: Prolance Micro Flow|DEVICE: Prolance Low Flow|DEVICE: Prolance Normal Flow|DEVICE: Prolance High Flow|DEVICE: Prolance Max Flow|DEVICE: Prolance Pediatric|DEVICE: Haemolance Micro Flow|DEVICE: Haemolance Low Flow|DEVICE: Haemolnace Normal Flow|DEVICE: Haemolance High Flow|DEVICE: Haemolance Max Flow|DEVICE: Haemolance Pediatric|DEVICE: MediSafe Solo 29 Gauge|DEVICE: MediSafe Solo 23 Gauge|DEVICE: ergoLance Micro Flow|DEVICE: ergoLance Normal Flow|DEVICE: ergoLance High Flow|DEVICE: Medlance (light blue)|DEVICE: Medlance (blue)|DEVICE: Medlance (dark blue)|DEVICE: Medlance (yellow)|DEVICE: Medlance (orange)|DEVICE: Medlance (red)|DEVICE: Unistik 3 Extra|DEVICE: Unistik 3 Comfort|DEVICE: Unistik Touch|DEVICE: ReadyLance (blue)|DEVICE: ReadyLance (orange)|DEVICE: AssureLance|DEVICE: AssureLance MicroFlow|DEVICE: Surgilance|DEVICE: Surgilance Lite (grey)|DEVICE: Surgilance Lite (purple)|DEVICE: SteriLance Lite2|DEVICE: SensiLance (pink)|DEVICE: SteriLance Press|DEVICE: SensiLance (orange)|DEVICE: mylife|DEVICE: VeriFine|DEVICE: Microdot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Open-label Extension Study to Assess Safety and Tolerability of LYC-30937-EC in Subjects With Active Ulcerative Colitis
Status: TERMINATED
Conditions: Colitis, Ulcerative
Interventions: DRUG: LYC-30937-EC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferumoxytol - Iron Oxide Nanoparticle Magnetic Resonance Dynamic Contrast Enhanced MRI
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Magnetic Resonance Imaging (MRI)|DRUG: Ferumoxytol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Web Based Education on the Level of Coping With Infertility Stress and Infertility Self-Efficacy
Status: COMPLETED
Conditions: Infertility, Female|Educational Problems|Intrauterine Insemination
Interventions: OTHER: Web-based patient education for the intrauterine insemination (IUI) treatment process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Safety and Effect of ThisCART19A in Patients With AIDS Related B Cell Lymphoma/Lympholeukemia
Status: UNKNOWN
Conditions: AIDS Related Lymphoma and Lympholeukemia
Interventions: BIOLOGICAL: ThisCART19A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptoms and Quality of Life (QoL) After Palliative Pelvic Radiation of Prostate and Rectal Cancers
Status: COMPLETED
Conditions: Prostatic Neoplasms|Rectal Neoplasms
Interventions: RADIATION: Palliative pelvic soft-tissue radiation (external beam)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiovascular Benefits of Acai Polyphenols in Volunteers at Risk of Metabolic Syndrome
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Acai puree, frozen blended it with banana|DIETARY_SUPPLEMENT: Control Macronutrient matched
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor
Status: COMPLETED
Conditions: Male Infertility|Infertility, Male
Interventions: OTHER: MicroFluidic Sperm Sorting Chips|OTHER: Gradient-Density Centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
Status: COMPLETED
Conditions: Missed Abortion
Interventions: DRUG: Misoprostol (given buccally)|DRUG: Misoprostol (given vaginally)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of APAP With SensAwake in OSA and Insomnia Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Insomnia
Interventions: DEVICE: APAP|DEVICE: APAP with SensAwake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Selenium for Bowel Polyps (OSCAR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Adenoma
Interventions: DRUG: Selenomethionine|DRUG: Methylselenocysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Danoprevir and Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: danoprevir|DRUG: danoprevir|DRUG: ritonavir|DRUG: ritonavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Two Types of Fixed Retainers on the Health of the Gums
Status: UNKNOWN
Conditions: Health of Periodontium
Interventions: DEVICE: Fiber-reinforced-composite retainer|DEVICE: Composite-wire retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial for Effect of TQB3616 Capsule on Pharmacokinetics in Healthy Adult Subjects
Status: COMPLETED
Conditions: Recurrent/Metastatic Breast Cancer
Interventions: DRUG: TQB3616 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basivertebral Nerve Block During Vertebral Augmentation: An Alternative Approach to Intraprocedural Pain Management
Status: COMPLETED
Conditions: Vertebral Compression|Vertebra Compression Fracture|Vertebral Fracture
Interventions: PROCEDURE: Basivertebral nerve block|DRUG: Lidocaine induced basivertebral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ADINA vs. High Flow Nasal Cannula Comparison Study
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Neonatal
Interventions: DEVICE: Adaptive Dynamic Inspiratory Nasal Apparatus|DEVICE: High flow Nasal Canula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention|Aging|Anticoagulants and Bleeding Disorders
Interventions: DRUG: Bivalirudin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin and FSHr|PROCEDURE: Ovarian drilling by FERTILOSCOPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Biphasic Insulin Aspart 50 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 50|DRUG: biphasic human insulin 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Performance of Ankle Ligament Supports in the Context of a Return to Sport After Sprain
Status: TERMINATED
Conditions: Ankle Sprain 1St Degree|Ankle Sprain 2Nd Degree|Ankle Sprain 3Rd Degree
Interventions: DEVICE: AnkleSTRONG100/500/900
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Efficacy of EUS-FNA/B Versus ERCP With or Without POCS-TB in Patients With Suspected Hilar Cholangiocarcinoma
Status: RECRUITING
Conditions: Klatskin Tumor|Cholangiocarcinoma|Biopsy, Fine-Needle|Endoscopic Retrograde Cholangiopancreatography
Interventions: DIAGNOSTIC_TEST: The sampling method selected in patients with suspected hilar cholangiocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects.
Status: COMPLETED
Conditions: Parkinson Disease|Huntington Disease
Interventions: DRUG: [123I]MNI-420
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiotherapy Prehabilitation in Patients Undergoing Cardiac or Thoracic Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Lung Cancer|Lung Tumor
Interventions: OTHER: Walking Programme|DEVICE: Incentive Spirometer|OTHER: Deep Breathing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studying Genes, Environment, and Prostate Cancer Risk in Patients With or Without Prostate Cancer
Status: COMPLETED
Conditions: Hereditary Prostate Cancer|Prostate Cancer
Interventions: GENETIC: DNA analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phosphatidylcholine (LT-02) vs. Placebo vs. Mesalamine for Maintenance of Remission in Ulcerative Colitis (PROTECT-2)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: LT-02|DRUG: Placebo|DRUG: Mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas
Status: NOT_YET_RECRUITING
Conditions: Periampullary Adenocarcinoma
Interventions: PROCEDURE: laparoscopic pancreaticoduodenectomy|PROCEDURE: open pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Safety, Tolerability, and the Way the Body Absorbs, Distributes, and Gets Rid of a Study Drug Called MOR106, in Healthy Subjects and in Patients With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Healthy|Atopic Dermatitis
Interventions: DRUG: MOR106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Memory Disorders|Cognitive Impairment|Dementia|Presymptomatic Disease
Interventions: OTHER: Altoida: neuropsychological, MRI, EEG and CSF biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol]
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth
Interventions: DRUG: Erythromycin|DRUG: Amoxicillin and Erythromycin|DRUG: Azithromycin|DRUG: Caffeine citrate: Low dose|DRUG: Caffeine citrate: Medium dose|DRUG: Caffeine citrate: High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen
Status: TERMINATED
Conditions: Multifollicular Stimulation
Interventions: DRUG: Recombinant-follicle stimulating hormone (r-FSH)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Double-blind, Placebo-controlled Clinical Study of the Oral IL-12/23 Inhibitor, STA-5326 Mesylate, Administered to Patients With Rheumatoid Arthritis to Determine Safety, Tolerability, Pharmacokinetic and Synovial Tissue Outcomes
Status: COMPLETED
Conditions: Active, Moderate to Severe Rheumatoid Arthritis
Interventions: DRUG: STA 5326 mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and Irritability
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Iloperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone in Children With Juvenile Rheumatoid Arthritis (JRA) and With Crohn's Disease
Status: TERMINATED
Conditions: Arthritis, Juvenile Rheumatoid|Crohn Disease
Interventions: DRUG: somatropin [rDNA origin] for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prometra Post-Approval Study
Status: COMPLETED
Conditions: Chronic Pain|Cancer Pain|Intractable Pain|Back Pain
Interventions: DEVICE: Prometra Programmable Intrathecal Infusion Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investıgatıon Of The Effectıveness Of The Mollıı Suıt In Chıldren Wıth Ambulatory Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Spasticity, Muscle
Interventions: DEVICE: EXOPULSE Mollii Suit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Obstructive Lung Disease (NOVELTY)
Status: COMPLETED
Conditions: Asthma|COPD|Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Blood draw|PROCEDURE: Urine|PROCEDURE: Lung function measurements|PROCEDURE: Fractional Exhaled Nitric Oxide (FENO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion
Status: RECRUITING
Conditions: Fallopian Tube Carcinosarcoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Ovarian Carcinosarcoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Serous Adenocarcinoma|Primary Peritoneal Carcinosarcoma|Primary Peritoneal Clear Cell Adenocarcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Pegcetacoplan|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hearing for Learning Initiative - a Health Facilitator Model for Otitis Media
Status: ACTIVE_NOT_RECRUITING
Conditions: Otitis Media|Conductive Hearing Loss
Interventions: BEHAVIORAL: facilitator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Effect of R1507 in Combination With Tarceva (Erlotinib) on Progression-Free Survival in Patients With Stage IIIb/IV Non-Small Cell Lung Cancer (NSCLC).
Status: TERMINATED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: RG1507|DRUG: RG1507|DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Optic Flow Speed Manipulation and the Level of Immersion on the Gait Pattern in People Post-stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Walking with different optic flow speeds with 2 different VR devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Pelvic Floor Training in Postmenopausal Women With or Without Hormonal Therapy
Status: COMPLETED
Conditions: Weak; Pelvic Floor|Weak; Muscle|Urinary Incontinence
Interventions: BEHAVIORAL: pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of AIV007 by Periocular Administration in Subjects With nAMD or DME
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema
Interventions: DRUG: AIV007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DSME or DSME + MI in T1DM on Glycemic Control
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Motivational interviewing|DRUG: DSME participants in this arm will receive standard care for diabetes (DSME) at the beginning of the study and 3 months later
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facts-Up-Front Versus Traffic-Light Food Labels
Status: COMPLETED
Conditions: Food Labeling
Interventions: BEHAVIORAL: Traffic Light|BEHAVIORAL: Traffic Light+|BEHAVIORAL: Facts Up Front|BEHAVIORAL: Facts Up Front+|BEHAVIORAL: No label control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)
Status: TERMINATED
Conditions: Mechanical Ventilation|Critical Illness
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Fentanyl|DRUG: Midazolam|BEHAVIORAL: Physical and Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intensive Training on Reocvery of Fingers Dexterity Following Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: Intensive Finger Individuation Therapy|COMBINATION_PRODUCT: Intensive non-directed finger movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of SensAwake™ for Continue Positive Airway Pressure Treatment of Obstructive Sleep Apnea Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: SensAwake™ modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy of Treatment vs Discontinuation in a First Episode of Non-affective Psychosis
Status: UNKNOWN
Conditions: Psychosis Nos/Other
Interventions: DRUG: Discontinuation antipsychotic treatment|DRUG: Antipsychotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abbreviated MAPK Targeted Therapy Plus Pembrolizumab in Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Study of Vildagliptin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Demcizumab|DRUG: Abraxane®|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevasizumab Versus Intravitreal Triamcinolone in Branch Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion
Interventions: DRUG: Bevacizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy
Status: RECRUITING
Conditions: Castration Resistant Prostate Cancer|Castration Sensitive Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: Piflufolastat|PROCEDURE: PSMA PET/CT Scan|PROCEDURE: PSMA PET/MRI scan|PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Effect of Rifampin and Rabeprazole on the Pharmacokinetics of Camlipixant
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Camlipixant + Rifampin|DRUG: Camlipixant + Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Therapy in the Temporomandibular Joint Dysfunction in Patients With Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Multidisciplinary therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Thrombocytopenia in Patients With Chronic Liver DiseaseUndergoing an Elective Procedure
Status: COMPLETED
Conditions: Thrombocytopenia Associated With Liver Disease
Interventions: DRUG: avatrombopag (lower baseline platelet count)|DRUG: placebo (lower baseline platelet count)|DRUG: avatrombopag (higher baseline platelet count)|DRUG: placebo (higher baseline platelet count)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Protein Source on Satiety and Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Casein-enriched diet|DIETARY_SUPPLEMENT: Milk soluble protein-enriched diet|DIETARY_SUPPLEMENT: Casein and milk soluble proteins-enriched diet|DIETARY_SUPPLEMENT: Soy proteins-enriched diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia-1|Cytopenia
Interventions: DIETARY_SUPPLEMENT: Vitamin C (ascorbic acid)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold
Status: RECRUITING
Conditions: OSA
Interventions: DRUG: Lemborexant 5 MG Oral Tablet [Dayvigo] Day 1|DRUG: Lemborexant 5 MG Oral Tablet [Dayvigo] Day 2|DRUG: Placebo Day 1|DRUG: Placebo Day 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Promoting Social-emotional Development and Self-esteem in Primary School Students
Status: RECRUITING
Conditions: Prosocial Behavior|Anxiety Disorders and Symptoms|Attention Deficit Hyperactivity Disorder|Healthy|Emotional Problem|Self Esteem|Peer Group
Interventions: BEHAVIORAL: HiRO|BEHAVIORAL: HiRO +judo|BEHAVIORAL: School as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thorough QT/QTc of Pritelivir in Healthy Subjects
Status: COMPLETED
Conditions: HSV Infection
Interventions: DRUG: Pritelivir and moxifloxacin placebo|DRUG: Pritelivir placebo, moxifloxacin and moxifloxacin placebo|DRUG: Pritelivir placebo, moxifloxacin placebo and moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ProGrip Mesh Repair vs Lichtenstein Operation
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DEVICE: Covidien Parietex ProGrip Self-Fixating Mesh|DEVICE: Lightweight Polypropylene Mesh (<38g/m2 after absorption)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypolipemic Treatment in Acute Coronary Syndrome (ACS): Antithrombotic Effects
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: simvastatin|DRUG: ezetimibe|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clonidine Versus Midazolam for Premedication
Status: COMPLETED
Conditions: Anxiety|Pain
Interventions: DRUG: midazolam|DRUG: clonidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotic Sport Study
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Endotoxemia
Interventions: DIETARY_SUPPLEMENT: probiotic-based dietary supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV|Inoperable Disease
Interventions: DRUG: Interleukin-2|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer|Rectosigmoid Cancer
Interventions: DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: Leucovorin|BIOLOGICAL: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence|Substance Abuse|Methamphetamine Abuse
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2
Status: UNKNOWN
Conditions: Covid19|ARDS, Human
Interventions: OTHER: High PEEP with end inspiratory pause|OTHER: Low PEEP - FiO2 high|OTHER: High PEEP without end inspiratory pause|OTHER: Low PEEP - FiO2 low
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease
Status: UNKNOWN
Conditions: Anemia, Sickle Cell|Chronic Pain
Interventions: DEVICE: tDCS plus PES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CyPep-1 Injections in Cancer Inducing Lymphocyte Infiltrate Accumulations
Status: COMPLETED
Conditions: Advanced Solid Tumor Malignancy
Interventions: DRUG: CyPep-1|DRUG: Pembrolizumab 25 MG/ML [KEYTRUDA®]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal 1.3-ß-D-glucan for the Diagnosis of Intra-abdominal Candidiasis in Critically Ill Patients (pBDG2)
Status: COMPLETED
Conditions: Intra Abdominal Infections|Candidiasis, Invasive|Peritoneal Candidiasis|Critically Ill
Interventions: DIAGNOSTIC_TEST: 1.3 BETA D GLUCAN
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacogenetic Study of Methylphenidate in Attention Deficit/Hyperactivity Disorder(ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Methylphenidate|Pharmacogenetics
Interventions: GENETIC: norepinephrine transporter polymorphism,
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Tislelizumab in Combination With Dasatinib and Quercetin in Resectable HNSCC (COIS-01)
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinomas
Interventions: DRUG: Tislelizumab + Dasatinib + Quercetin (neoadjuvant)|PROCEDURE: surgery|DRUG: Tislelizumab + Dasatinib + Quercetin (adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LipoAerosol© Inhalation After Tracheostomy
Status: COMPLETED
Conditions: Other Tracheostomy Complication
Interventions: DEVICE: LipoAerosol© inhalation|OTHER: Physiologic saline inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Quality of Life of Patients Requiring Intestinal Cleansing Using Oral Medications to Imaging Procedure by Patient Reported Outcome
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DRUG: Oral Sodium Phosphate - Normal preparation|DRUG: Oral sodium phosphate - Modified Preparation|DRUG: polyethylene glycol + Electrolytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy, Immunogenicity and Safety of an EV71 Vaccine in Healthy Infants and Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Enterovirus Infections
Interventions: BIOLOGICAL: EV71 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging in Evaluating Response to RadiationTherapy in Patients With High Grade Glioma
Status: COMPLETED
Conditions: Brain Tumor
Interventions: PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Diffusion Tensor Imaging|PROCEDURE: Magnetic Resonance Spectroscopic Imaging|PROCEDURE: Dynamic Contract-Enhanced magnetic resonance imaging|PROCEDURE: Diffusion-weighted magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Superficial Cervical Plexus Block for Improved Outcomes in Pediatric Otolaryngologic Surgery
Status: RECRUITING
Conditions: Otolaryngologic Surgery
Interventions: DRUG: ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Escalation Phase 1 Study of G-202 (Mipsagargin) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: G-202
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT