pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: APX001 with Standard of Care anti-fungal agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacovigilance Study to Evaluate Safety of SERETIDE in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol/Fluticasone propionate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Intracranial Stent (Tonbridge) in Endovascular Treatment of Symptomatic Intracranial Atherosclerotic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Intracranial Atherosclerosis
Interventions: DEVICE: Intracranial Stent (Tonbridge)|DEVICE: Wingspan Stent System (Stryker Neurovascular)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing Osteoarthritic Joints in the Wrist With Adult ADRCs
Status: RECRUITING
Conditions: Osteoarthritis of the Wrist
Interventions: DEVICE: adipose-derived stem cell injection|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Two Dosing Schedules of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: adalimumab|DRUG: placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of TWP-201 in Healthy Female Subjects
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: TWP-201|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death
Status: COMPLETED
Conditions: Pulmonary Hypertension|Bronchopulmonary Dysplasia|Respiratory Distress Syndrome
Interventions: BEHAVIORAL: CPR instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: ECT
Clinical trial: Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study.
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: DIAGNOSTIC_TEST: 18F-GE-180 PET|DIAGNOSTIC_TEST: Advanced MRI|OTHER: Collection of hematopoietic stem cells|OTHER: Blood withdrawal|OTHER: Collection of Cancer Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal Hypertension
Status: UNKNOWN
Conditions: Gastroesophageal Varices|Hypersplenism|Portal Hypertension
Interventions: DEVICE: coils|DRUG: cyanoacrylate glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected Persons
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: VRC07-523LS|DRUG: Vorinostat (VOR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of BIBR 1048 MS Single Doses With or Without Pantoprazole in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS capsule formulation A|DRUG: BIBR 1048 MS capsule formulation B|DRUG: BIBR 1048 MS powder plus solution|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Once Daily Oral Administration of AZD5004 Versus Placebo for 26 Weeks in Adults With Type 2 Diabetes Mellitus.
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo (placebo matching AZD5004 film-coated tablet)|DRUG: AZD5004|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelial Bleb Response With Toric Lenses
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: alphafilcon A toric|DEVICE: lotrafilcon B toric|DEVICE: senofilcon A toric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: WASH Benefits Kenya
Status: COMPLETED
Conditions: Malnutrition|Diarrhea|Child Development
Interventions: BEHAVIORAL: Water Quality|BEHAVIORAL: Sanitation|BEHAVIORAL: Handwashing|DIETARY_SUPPLEMENT: Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Inpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Divalproex Sodium (Depakote ER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Placebo Study to Determine the Effectiveness of Theramine on the Management of Chronic Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Theramine (A medical food)|DRUG: Theraprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split Renal Function Using 99mTc-DTPA Versus 99mTc-DMSA in Kidney Patients of Wide Age Ranges.
Status: UNKNOWN
Conditions: The Difference in Estimation of Split Renal Function Using the Two Radiopharmaceuticals:Tc-99m DTPA & Tc-99m DMSA in Kidney Patients
Interventions: OTHER: renal scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence, on Agonist Therapy
Interventions: DRUG: Higher bioavailability BNX sublingual tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery
Status: COMPLETED
Conditions: Elevated Cardiac Risk|Coronary Arteries Disease Risk
Interventions: DRUG: Xenon|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
Status: NOT_YET_RECRUITING
Conditions: IgA Nephropathy|Lupus Nephritis (LN)|C3 (Complement Component 3) Glomerulopathy
Interventions: DRUG: ADX-097
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: N-Acetyl Cysteine Plus Naltrexone in Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Naltrexone plus N-Acetyl Cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Rivroxaban to Coumadin( Warfarin ) in Cerebral Venous Thrombosis
Status: UNKNOWN
Conditions: Cerebral Venous Thrombosis
Interventions: DRUG: Coumadin|DRUG: Rivoroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Anyu Peibo With Placebo in Treatment of MDD，Ⅱb
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Anyu Peibo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis and Clinical Presentation of Iliac Graft-Enteric Fistula: A Case Report
Status: NOT_YET_RECRUITING
Conditions: Case-report|Diagnosis|Digestive System Fistula|Gastrointestinal Hemorrhage|Iliac Graft-Enteric Fistula
Interventions: DIAGNOSTIC_TEST: ct scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Conservative Treatment Versus Operative Plate Fixation for Acute, Displaced Fractures of the Distal Clavicle
Status: COMPLETED
Conditions: Clavicle Fracture|Fractures
Interventions: PROCEDURE: Non-operative Treatment|PROCEDURE: Operative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Transdermal Estradiol on Female COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19|Hormone Replacement Therapy
Interventions: DRUG: Climara 0.1Mg/24Hr Transdermal System|OTHER: Hydrogel patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Electroacustimulation on Postoperative Nausea, Vomiting and Pain in Outpatient Plastic Surgery Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: Electroacustimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Maxillary Acrylic Resin Complete Dentures Reinforced by Gold Plated Cr-Co Palatal Plate
Status: UNKNOWN
Conditions: Denture Stomatitis
Interventions: DEVICE: Gold plated chrome cobalt alloy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD
Status: RECRUITING
Conditions: Acute Graft Versus Host Disease
Interventions: DRUG: MTX|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Internet-based Cognitive Behaviour Therapy for Adolescents With Co-morbid Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Internet-based Cognitive Behaviour Therapy (iCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: T-DXd|BIOLOGICAL: Durvalumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Volrustomig|DRUG: Rilvegostomig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh
Status: COMPLETED
Conditions: Uncomplicated Falciparum Malaria
Interventions: DRUG: azithromycin plus artesunate|DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Bioequivalence of Metered Dose Inhalers of Albuterol Sulfate in Patients With Stable Mild Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: 90 mcg Reference Product|DRUG: 180 mcg Reference Product|DRUG: 90 mcg Test Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Status: WITHDRAWN
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Spinal Anesthesia + ACB continious catheter + iPACK + Sham LIA|PROCEDURE: Spinal Anesthesia + LIA + Sham Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial to Evaluate the UNI-DEB for Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DEVICE: UNI-DEB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: HC-7366|DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSTC1 for Diabetic Foot Ulcers Phase II Study
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetes Mellitus|Wounds
Interventions: DRUG: CSTC1|DRUG: CSTC1 Matched vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuously Coached Practice Using EMS on ERCP Performance of Trainees
Status: SUSPENDED
Conditions: Selective Cannulation Rate of Trainees Receiving ERCP Training
Interventions: DEVICE: Hands-on EMS training|OTHER: Standard training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of Newly-created Individualized Upper Airway Muscle Functional Training on Patients With OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Muscle Disorder
Interventions: BEHAVIORAL: New individualized upper airway muscle functional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05528)(COMPLETED)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Mometasone furoate nasal spray (MFNS)|DRUG: Matching placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiology, Imaging and Modeling of Essential Tremor
Status: RECRUITING
Conditions: Essential Tremor|Parkinson Disease|Dystonia
Interventions: DEVICE: Active biphasic pulse stimulation---Home Settings|DEVICE: Active biphasic pulse stimulation---VIN Biphasic|DEVICE: Active biphasic pulse stimulation---Stimulator Off
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant or Adjuvant Chemotherapy in Patients With Operable Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: Neoadjuvant chemotherapy (taxol and carboplatin)|DRUG: Adjuvant chemotherapy (taxol and carboplatin)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Oral Care With Vaccines for Pneumonia in Elderly; Going Home Together Both Physician and Dentist
Status: COMPLETED
Conditions: Pneumonia
Interventions: BIOLOGICAL: Pneumococcal vaccination (Pneumovax NP, 21800AMY10131000)|BIOLOGICAL: Influenza vaccination (Flubik HA, 16100EZZ01207000)|BIOLOGICAL: Influenza vaccination (Flubik HA, 16100EZZ01207000)|OTHER: Specific frequency of oral care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: V503 in Chinese Girls 9-14 Years Old Versus Chinese Women 20-26 Years Old (V503-071)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: 9vHPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: E-bibliotherapy for Informal Caregivers of People With Dementia
Status: NOT_YET_RECRUITING
Conditions: Dementia|Caregiver Stress Syndrome|Psychological Well-Being
Interventions: OTHER: E-bibliotherapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Abiraterone acetate tablets(Zecke ®250 mg);Abiraterone acetate tablets(250 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Bone Pain|Metastatic Malignant Neoplasm in the Bone|Plasma Cell Myeloma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Level and Cognitive Functions in Children With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: PAQ-C (Physical activitiy questionare for children), MoCA (Montreal Cognitive Assessment), PBS (Pediatric Balance Scale), Modified Mini Mental State Examination, BMI (Body Mass Index)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Compare the Safety,Tolerability and Efficacy of Influenza Virus Vaccine, (CAIV-T) With Influenza Virus Vaccine, Trivalent, Inactivated (TIV) in Children
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: BIOLOGICAL: CAIV-T or TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Shock, Surgical|Shock|Hypotension and Shock|Kidney Transplant; Complications|Intraoperative Hypotension|Postoperative Hypotension
Interventions: DRUG: Angiotensin II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Posterior left pericardiotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Buttermilk on Serum LDL Cholesterol Concentrations
Status: COMPLETED
Conditions: Hypercholesterolemia|Buttermilk|Dietary Modification|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Buttermilk without added egg-yolk|DIETARY_SUPPLEMENT: Buttermilk with added egg yolk|DIETARY_SUPPLEMENT: Skimmed milk with added egg-yolk|DIETARY_SUPPLEMENT: Skimmed milk without added egg yolk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prebiotic Fibre Supplementation and Gut Microbiota in Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Prebiotic fibre|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Leukemia, Myeloid, Acute|Renal Insufficiency|Liver Disease|Neoplasms
Interventions: DRUG: Azacitidine|DRUG: Pevonedistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Self-conditioning Techniques in Promoting Weight Loss in Patients With Obesity. A Randomized Controlled Trial
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: self-conditioning techniques|OTHER: standard care (diet, exercise and behavioral therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability of AG-348 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C]AG-348 and Concomitant Single Intravenous Microdose of [13C6]AG-348
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AG-348|DRUG: [13C6]AG-348
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ruxolitinib and Duvelisib in People With Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: T-cell Lymphomas|NK-Cell Lymphomas|T-cell Prolymphocytic Leukemia|T-cell Large Granular Lymphocyte Leukemia
Interventions: DRUG: Ruxolitinib|DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MagnezixKids Study
Status: COMPLETED
Conditions: Magnesium-based|Bioresrobable Implants|Pediatric Elbow Fractures|Osteosynthesis|Childhood|Magnezix|Elbow Fracture
Interventions: DEVICE: Osteosynthesis with resorbable Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sotatercept (ACE-011) With Lenalidomide or Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: ACE-011|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Dapsone 5.0% Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone 5.0% Gel (SEEGPharm)|OTHER: Placebo|DRUG: Dapsone 5.0% Gel (Allergan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma
Status: RECRUITING
Conditions: Melanoma|Melanoma (Skin)|Melanoma Stage III|Melanoma Stage IV|Melanoma Unresectable|Melanoma Metastatic|Melanoma Advanced
Interventions: BIOLOGICAL: BCD-217|BIOLOGICAL: BCD-100|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Regularization in Patients With Permanent Atrial Fibrillation Post Marketing Study
Status: COMPLETED
Conditions: Permanent Atrial Fibrillation
Interventions: DEVICE: Vitatron pacemaker C20 SSIR or T20 SSIR models
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Sodium Fluoride (NaF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation and Dose Expansion Trial of WTX212A in the Treatment of Patients With Advanced Malignant Tumors
Status: RECRUITING
Conditions: Unresectable or Metastatic Advanced Solid Tumors
Interventions: DRUG: WTX212A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREVAIL: PREvention of VTE After Acute Ischemic Stroke With LMWH Enoxaparin ( - VTE: Venous Thromboembolism - LMWH: Low Molecular Weight Heparin)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DEVICE: Intracavitary Applicator Placement|OTHER: Computed Tomography (CT)|OTHER: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of LI4 Acupressure on Perineal Pain and Postpartum Comfort During Episiotomy Repair
Status: NOT_YET_RECRUITING
Conditions: Labor Pain|Perineal Pain|Postpartum Comfort
Interventions: OTHER: Acupressure group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia
Status: COMPLETED
Conditions: Hyperopia|Astigmatism
Interventions: DEVICE: Technolas 217z Zyoptix Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of TCI378 and TCI507 Probiotics on Weight-lowering Efficacy in Adults
Status: RECRUITING
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: TCI378 Probiotics|DIETARY_SUPPLEMENT: TCI507 Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Home-based Exercise and Physical Activity Intervention After Liver Transplantation: Impact of Exercise Intensity
Status: RECRUITING
Conditions: Liver Transplantation|Physical Fitness
Interventions: OTHER: Physical activity|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular Lymphoma
Status: COMPLETED
Conditions: B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma|Central Nervous System Lymphoma|Intraocular Lymphoma|Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System|Recurrent Adult Diffuse Large Cell Lymphoma|Retinal Lymphoma
Interventions: DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Efficacy and Security Analysis in the Protection of Ileocolic Anastomosis Conducted in Laparoscopic Right Hemicolectomy Because of Colon Cancer, Using a NHS-PEG Coated Collagen Patch.
Status: UNKNOWN
Conditions: Adenocarcinoma Colon
Interventions: OTHER: NHS-PEG coated collagen patch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Fluocinonide 0,05% in Oral Lichen Planus
Status: RECRUITING
Conditions: Oral Lichen Planus
Interventions: DRUG: Fluocinonide 0,05% oral gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Hepatitis C, Chronic
Interventions: DRUG: E/C/F/TAF;|DRUG: Ledipasvir-Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Utilizing a Computerized Cognitive Rehabilitation Program (D-kit/EF1)
Status: RECRUITING
Conditions: Mild Intellectual Disability|Borderline Intellectual Functioning
Interventions: DEVICE: D-kit/EF1|DEVICE: Sham group program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphomas
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia ,Lymphomas
Interventions: BIOLOGICAL: Anti-CD19 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Diabetic Foot
Status: COMPLETED
Conditions: Ulcers Related to Diabetic Foot Syndrome
Interventions: DRUG: Neovasculgen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Foot Reflexology on Blood Pressure and Pulse Rate: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Reflexology, Hypertension, Acupressure, Traditional Medicine
Interventions: PROCEDURE: foot reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Comparative Trial of DOX-SL (Stealth Liposomal Doxorubicin Hydrochloride) Versus Bleomycin and Vincristine in the Treatment of AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Doxorubicin hydrochloride (liposomal)|DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Bryostatin-1 Effect on HIV-1 Latency and Reservoir in HIV-1 Infected Patients Receiving Antiretroviral Treatment
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Placebo|DRUG: Bryostatin 1 (10ug/m2)|DRUG: Bryostatin 1 (20ug/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Fatigue|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: St. John's wort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Carbohydrate Consumption on Memory Performance and Mood in Children
Status: COMPLETED
Conditions: Cognitive Ability, General
Interventions: OTHER: Meal Skipping|OTHER: French fries|OTHER: Mashed potatoes|OTHER: Hash browns|OTHER: Rice|OTHER: Beans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IDG-16177 for the Evaluation of Its Safety and Pharmacokinetics
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: [Part 1.1] IDG-16177|DRUG: [Part 1.1] Placebo of IDG-16177|DRUG: [Part 2] Sitagliptin|DRUG: [Part1.2] IDG-16177|DRUG: [Part 2] IDG-16177|DRUG: [Part 1.2] Placebo of IDG-16177|DRUG: [Part 2] Placebo of IDG-16177
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HL Tablet in Non-alcoholic Fatty Liver Disease Patients
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: HL tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Intervention for Acute Stress
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Chronic Obstructive Pulmonary Disease|Overlap Syndrome
Interventions: DEVICE: bi-level positive pressure non invasive ventilation|DRUG: Oxygen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Length of Second Stage of Labor in Primigravidae on Maternal & Neonatal Outcomes
Status: UNKNOWN
Conditions: The Length of Second Labor Stage in Primigravidae on Maternal & Neonatal Outcomes
Interventions: BEHAVIORAL: Coached pushing group|BEHAVIORAL: uncoached pushing group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Oral Tofacitinib in the Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Extensive Alopecia Areata
Interventions: DRUG: Oral Tofacitinib citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Tension on Human Embryonic Development
Status: COMPLETED
Conditions: Infertility|Embryo Culture|Hypoxia
Interventions: OTHER: 20% oxygen|OTHER: 5% oxygen|OTHER: 20 % and 5 % oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study)
Status: RECRUITING
Conditions: Severe Dengue
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Musical Intervention on Prevalence and Severity of Paroxysmal Sympathetic Hyperactivity After Severe Traumatic Brain Injury
Status: TERMINATED
Conditions: Paroxysmal Sympathetic Hyperactivity
Interventions: OTHER: Musical intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Levonorgestrel/Ethinyl Estradiol Tablets 0.1 mg/0.02 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Levonorgestrel 0.1 mg and Ethinyl estradiol 0.02 mg Test Product|DRUG: Levonorgestrel 0.1 mg and Ethinyl estradiol 0.02 mg Reference Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liver Transplantation in Patients With Incidental Hepatocellular-cholangiocarcinoma and Intrahepatic Cholangiocarcinoma: A Single-center Experience
Status: UNKNOWN
Conditions: Adult Combined Hepatocellular-Cholangiocarcinoma
Interventions: PROCEDURE: liver transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupuncture Therapy VS Chiropractor Group Therapy to Reduce Anxiety and Depression.
Status: ENROLLING_BY_INVITATION
Conditions: Anxiety Depression|HIV/AIDS
Interventions: OTHER: Acupuncture|OTHER: Chiropractic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Calcium Plus Vitamin D Supplementation in Prevention of Colorectal Adenomas Recurrence
Status: UNKNOWN
Conditions: Colorectal Adenoma
Interventions: DRUG: Ca plus vit D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Down Syndrome
Interventions: DRUG: Placebo|DRUG: AEF0217
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Magnetic therapy|DEVICE: laser therapy|DRUG: Only medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Screening Among Men With High Risk Genetic Predisposition
Status: UNKNOWN
Conditions: BRCA1 Syndrome|BRCA2 Syndrome|Lynch Syndrome
Interventions: OTHER: PSA|OTHER: IPSS questionnaire|OTHER: DRE (Digital Rectal Examination )|OTHER: urine flow and residual|PROCEDURE: a multiparametric prostate MRI|PROCEDURE: trans-rectal ultra-sound guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Non-eugenol Periodontal Pack With and Without PRF on Post-operative Pain and Wound Healing After Gingival Depigmentation
Status: UNKNOWN
Conditions: Gingival Pigmentation
Interventions: BIOLOGICAL: PRF under non-eugenol containing periodontal pack|OTHER: Non-eugenol containing periodontal pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DIAGNOSTIC_TEST: Blood test - atomic force microscopy in the force spectroscopy mode
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Psychological Impact of Group Therapy for Patients Who Have Been Hospitalized in Intensive Care During COVID-19 Pandemic: Exploratory Study
Status: COMPLETED
Conditions: Intensive Care Unit Syndrome|Covid19|Anxiety|Depression
Interventions: OTHER: therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of TECAR in Treating Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: TECAR followed by pelvic floor exercises|OTHER: pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cadonilimab Combined With Regorafenib in Patients With Advanced HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Cadonilimab+regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Nutraceutical in Raising Circulating Serum Vitamin, Mineral and Amino Acid Levels in Patients.
Status: COMPLETED
Conditions: Vitamin Deficiency
Interventions: DIETARY_SUPPLEMENT: EZPAK|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quality of Life in Patients Undergoing Total Pelvic Exenteration
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Exenteration|Anterior or Posterior Pelvic Exenteration|Gynecologic Malignancies|Colorectal Malignancies|Urologic Malignancies
Interventions: BEHAVIORAL: questionnaires/interviews
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Intratumoral IMO-2125 in Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors|Melanoma
Interventions: DRUG: IMO-2125
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Hyoscine Butyl Bromide With Cervical Lidocaine Cream in Reducing Pain During Hysterosalpingography
Status: COMPLETED
Conditions: Pain Relief
Interventions: DRUG: oral hyoscine butyl bromide tablets plus lidocaine cream|DRUG: oral placebo tablets plus placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy|Endothelial Dysfunction
Interventions: BIOLOGICAL: BNP blood sample test|DIAGNOSTIC_TEST: Electrocardiogram|DIAGNOSTIC_TEST: Holter ECG|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Air venous plethysmography|DIAGNOSTIC_TEST: Upper member arterial Doppler echography with analysis of FMD|BIOLOGICAL: Endothelial function biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety & Performance Study of Lumen Biomedical's FiberNet Distal Protection System for the Treatment of Renal Artery Stenosis
Status: UNKNOWN
Conditions: Renal Stenting in the Treatment of Pts w/a High Grade Ostial Atherosclerotic Renal Lesion(s).
Interventions: DEVICE: Lumen Biomedical FiberNet Embolic Protection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study
Status: RECRUITING
Conditions: May-Thurner Syndrome
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin|DRUG: Nadroparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation With Enhanced Gastrointestinal Safety (AEGIS) Trial
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: BEHAVIORAL: Clinician notification|BEHAVIORAL: Clinician Notification with Nurse Facilitation|BEHAVIORAL: Clinician Notification / Patient Activation|BEHAVIORAL: Clinician Notification with Nurse Facilitation / Patient Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ponatinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) (EPIC)
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: ponatinib|DRUG: imatinib (Gleevec/ Glivec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver Interventions for Developmental Delays in Young Kenyan Children
Status: COMPLETED
Conditions: Child Development|Parenting|Cognitive Developmental Delay
Interventions: BEHAVIORAL: Mother groups using principles of UNICEF/World Health Organization's Care for Child Development
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intensive Symptom Surveillance Guided by Machine Learning-Directed Risk Stratification in Patients With Non-Metastatic Head and Neck Cancer, The INSIGHT Trial
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Palliative Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-operative Chemotherapy in Operable Breast Cancer, Phase III Study Comparing a Short Intensive Pre-operative Chemotherapy With the Same Therapy Initiated Shortly After Surgery(Peri-operatively)(POCOB)EORTC 10902)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Fluorouracil/Epirubicin/Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Oophorectomy Versus Ovarian Conservation
Status: COMPLETED
Conditions: Oophorectomy|Hysterectomy
Interventions: PROCEDURE: Bilateral salpingo-oophorectomy|PROCEDURE: Ovarian conservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION