pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacist Intervention to Decrease Medication Errors in Heart Disease Patients (The PILL-CVD Study)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Heart Failure
Interventions: BEHAVIORAL: Pharmacist Intervention for Low-Literacy in Cardiovascular Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma
Status: COMPLETED
Conditions: Allergy|Asthma|Rhinitis
Interventions: DRUG: Mitizax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Glutamine on Muscle Mass and Function in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: L-Glutamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The UNSCARRed Study: UNresctable Squamous Cell Carcinoma Treated With Avelumab and Radical Radiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Skin
Interventions: COMBINATION_PRODUCT: Avelumab and Radical radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Powered Vascular Stapler in Video-Assisted Thoracoscopic (VAT) Lobectomies
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DEVICE: Surgeon's 'standard of care' stapler|DEVICE: Ethicon Powered Vascular Stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Status: COMPLETED
Conditions: Vertebral Artery Dissection|Cerebrovascular Accident|Stroke
Interventions: OTHER: Head positions and spinal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) Compared to the Current Marketed Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Advil PM Liqui-Gels Minis|DRUG: Advil PM Liqui-Gels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suxiao Jiuxin Pills in Microvascular Obstruction in Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Suxiao Jiuxin Pills|DRUG: The placebo of Suxiao Jiuxin Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Effects of Low Level Laser Therapy in the Physical Training and the Muscle Responses in Humans.
Status: COMPLETED
Conditions: Healthy Young Male Volunteers|Non Athletes|Free of Metabolic Disease|Joint, Bone and Muscles of Lower Limbs Free of Any Disease
Interventions: DEVICE: Photon stimulation by low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Bromocriptine Quick Release (BCQR) as Adjunct Therapy in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Bromocriptine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL
Status: NOT_YET_RECRUITING
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Venetoclax|DRUG: Inotuzumab ozogamicin|DRUG: Blinatumomab|DRUG: 6-mercaptopurine|DRUG: Methotrexate|DRUG: Cytarabine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Volume Responsiveness in Presence of Left Ventricular Diastolic Dysfunction
Status: UNKNOWN
Conditions: Hemodynamics
Interventions: OTHER: passive leg raising|OTHER: premedication|OTHER: intubation and mechanical ventilation|OTHER: central venous catheter|OTHER: arterial catheter|OTHER: transesophageal echocardiography|OTHER: transpulmonary thermodilution catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Feasibility Study of Mindfulness-Oriented Recovery Enhancement With Pregnant Women With Opioid Use Disorder
Status: TERMINATED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Similarity Prospective Phase 3 Study in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: CT-P10|DRUG: Rituxan|DRUG: MabThera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Parent Training Program for Parents of Children Adopted Internationally
Status: COMPLETED
Conditions: Attachment Disorders
Interventions: BEHAVIORAL: ABC for Children Adopted Internationally|BEHAVIORAL: DEF for Children Adopted Internationally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: SR-T100 gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (EU Extension Study)
Status: COMPLETED
Conditions: Primary Immunodeficiency (PID)
Interventions: BIOLOGICAL: IgPro20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Severity of Female SUI by Measuring New Static and Dynamic Ultrasound Parameters of the Urethra
Status: COMPLETED
Conditions: Incontinence, Urinary
Interventions: OTHER: Pelvic ultrasound / Urodynamic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Technology Supported High Intensity Training in Chronic Low Back Pain: the Techno-HIT Trial
Status: RECRUITING
Conditions: Chronic Low-back Pain|Exercise Therapy|Telerehabilitation
Interventions: OTHER: Technology supported High Intensity Training|OTHER: Moderate Intensity Training|OTHER: High Intensity Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of an Interdisciplinary, Nurse-coordinated Atrial Fibrillation Expert Program for Primary Care Patients
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: Care provided by AF expert program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: OCT or Angiography Guided De-escalation of DAPT
Status: NOT_YET_RECRUITING
Conditions: Optical Coherence Tomography|Dual Antiplatelet Therapy|Antiplatelet De-escalation|Neointimal Coverage|ST Elevation Myocardial Infarction
Interventions: PROCEDURE: OCT-guided PCI|PROCEDURE: Conventional angiography-based PCI|DRUG: DAPT de-escalation|DRUG: default DAPT regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® Ointment 0.1% in Treating Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Lindioil ointment|DRUG: Protopic ointment 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat
Status: UNKNOWN
Conditions: Preterm Labor Without Delivery|Pregnancy Preterm
Interventions: DRUG: Nifedipine|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: filgrastim|DRUG: melphalan|PROCEDURE: autologous peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-health Enhanced Motor-cognitive Training for AED Discharged Older Adults With Cognitive Frailty
Status: RECRUITING
Conditions: Frailty|Mild Cognitive Impairment
Interventions: BEHAVIORAL: E-health enhanced motor-cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant Chemoradiotherapy
Status: RECRUITING
Conditions: Rectal Cancer|Lymph Node Cancer Metastatic
Interventions: PROCEDURE: ICG-guided lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Simulation as Part of the Procedure Tracheobronchial Aspiration
Status: COMPLETED
Conditions: Tracheobronchial Anomalies
Interventions: PROCEDURE: The tracheobronchial aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MultiPulse Therapy (MPT) for AF (US)
Status: TERMINATED
Conditions: Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: DEVICE: Multi Pulse Therapy as delivered from the Cardialen External Stimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Single-dose Escalation Study of SQ-001 Infusion to Characterize the PK Profiles of Major Sentinel Compounds in Healthy Adult Volunteers in US
Status: COMPLETED
Conditions: Solid Tumor Refractory to Standard Therapy
Interventions: DRUG: SQ001 125mL/day|DRUG: SQ001 250mL/day|DRUG: SQ001 500mL/day|DRUG: SQ001 625mL/day|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ADVAIR 100/50mcg|DRUG: ADVAIR 250/50mcg|DRUG: ADVAIR 500/50mcg|DRUG: FLOVENT 100mcg|DRUG: FLOVENT 250mcg|DRUG: FLOVENT 500mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Practical Evidence of Antidiabetic Combination Therapy in Korea
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: alogliptin|DRUG: Pioglitazone|DRUG: alogliptin + pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Inactivated Vaccine in Healthy Adults Against Coronavirus Disease of 2019 (COVID-19)
Status: UNKNOWN
Conditions: COVID-19|Vaccine Reaction|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Covi Vax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pivotal 1 Study of RGX-314 Gene Therapy in Participants With nAMD
Status: RECRUITING
Conditions: AMD|nAMD|Wet Age-related Macular Degeneration|wAMD|Wet AMD|CNV
Interventions: GENETIC: RGX-314|GENETIC: RGX-314|BIOLOGICAL: Ranibizumab (LUCENTIS®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vandetanib, Carboplatin, and Paclitaxel in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer That Can Be Removed by Surgery
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: Zactima|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Phacotube vs Phacotrabeculectomy:A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Glaucoma|Cataract
Interventions: PROCEDURE: Glaucoma Implant Surgery|PROCEDURE: trabeculectomy|PROCEDURE: phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Long-acting Bupivacaine In Lower Extremity Amputation
Status: TERMINATED
Conditions: Amputation|Anesthesia, Local|Opioid Use
Interventions: DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Serologically Active, Clinically Stable Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Pharmacokinetics of Vedolizumab in Healthy Participants Following Single Subcutaneous Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vedolizumab SC|DRUG: Vedolizumab IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery
Status: RECRUITING
Conditions: Brain Metastases, Adult
Interventions: RADIATION: Stereotactic radiosurgery|DIAGNOSTIC_TEST: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coronary Artery Plaque Burden in Stable Angina and Non-obstructive Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Plaque, Atherosclerotic
Interventions: DIAGNOSTIC_TEST: Coronary artery plaque assessment by CT coronary angiography QAngio CT RE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Treprostinil and a New Formulation of LY900014 in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treprostinil|DRUG: Placebo|DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System
Status: RECRUITING
Conditions: Tricuspid Regurgitation Functional
Interventions: DEVICE: CI Percutaneous Ring Annuloplasty System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo|DRUG: Exenatide|DRUG: Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inter-individual Variation in the Blood Pressure Lowering Effects of Dietary Nitrate
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Beet It Sport Shot|DIETARY_SUPPLEMENT: Beet It Sport Shot Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: clonidine|DRUG: methylphenidate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia|Elevated Cholesterol
Interventions: DRUG: Inclisiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effect of Two Peripheral Nerve Blocks for Hip Surgery in Pediatrics
Status: COMPLETED
Conditions: Pain, Postoperative|Developmental Dysplasia of the Hip|Regional Anesthesia Morbidity
Interventions: PROCEDURE: FTPB|PROCEDURE: PENG Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes
Status: TERMINATED
Conditions: Gait Disorders, Neurologic
Interventions: DEVICE: Force platform and electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Answering Questions About Vitamin D Supplementation and Sun Exposure in Patients Who Have Undergone Surgery for Stage IB, Stage II, or Stage IIIA Melanoma
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Cerebral Ventricular Dilatations and Cerebrospinal Fluid Pulsations on Periventricular White Matter in Hydrocephalic Patients
Status: RECRUITING
Conditions: Hydrocephalus|Cerebral Ventricle|Cerebrospinal Fluid|White Matter Fiber
Interventions: OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
Status: NOT_YET_RECRUITING
Conditions: Hypertension, Pregnancy-Induced
Interventions: DRUG: Nifedipine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dual Targeting of Vascular Endothelial Growth Factor-A Together With Angiopoietins in Chemotherapy-naïve Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: AMG386 and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rifampicin on the Pharmacokinetics of Apatinib
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Apatinib Mesylate Tablets|DRUG: Rifampicin Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methods for Prevention of Urinary Tract Infection Following Botox Injection
Status: TERMINATED
Conditions: Overactive Bladder|Urinary Tract Infections
Interventions: DRUG: Periprocedural Antibiotics|DRUG: Extended Antibiotics|PROCEDURE: Injection of OnabotulinumtoxinA (BTX-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of OM-85 on Bronchiectasis Exacerbation
Status: COMPLETED
Conditions: Bronchiectasis With Acute Exacerbation
Interventions: DRUG: OM-85 BV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight Infants
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis|Very Low Birth Weight Infants
Interventions: DRUG: Saccharomyces boulardii|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The ESTxENDS Trial- Substudy on the Effects of Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig) on Respiratory Symptoms
Status: COMPLETED
Conditions: Smoking Cessation|Respiratory Disease
Interventions: OTHER: ENDS (vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rgp120/HIV-1IIIB|BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.
Status: NOT_YET_RECRUITING
Conditions: Necrotic Pulp|Apical Periodontitis
Interventions: DRUG: Diclofenac Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Pedometers for the Assessment and Enhancement of Mobility in Gynaecological and Oncological Patients Following Surgery.
Status: UNKNOWN
Conditions: Surgery|Mobilization|Gynecologic Cancer
Interventions: DEVICE: 4 VIVOFIT-
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Men's Prevention Apps to Research Efficacy
Status: COMPLETED
Conditions: HIV/AIDS|Sexually Transmitted Diseases|Pre-exposure Prophylaxis|Risk Reduction
Interventions: BEHAVIORAL: LYNX|BEHAVIORAL: MyChoices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Team Debriefing With Instructor vs Team Debriefing Without Instructor After Simulating a Vital Emergency in a Multidisciplinary Team
Status: UNKNOWN
Conditions: High Fidelity Simulation Training|Simulation Training
Interventions: OTHER: debriefing without instructor|OTHER: debriefing with instructor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Learning Algorithm for MDI Individuals With Type 1 Diabetes to Adjust Recommendations for High Fat Meals and Exercise Management
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Sensor augmented MDI therapy plus mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Upper Extremity Function and Trunk Stability After Cervical Spinal Cord Injury (SCI)
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Spinal Cord Injury
Interventions: BEHAVIORAL: FTP Alone|BEHAVIORAL: FTP+Con-FES|BEHAVIORAL: FTP+WPHF-FES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: RO7283420|DRUG: RO7283420|DRUG: Tocilizumab|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Paracetamol/acetaminophen|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Chemoprevention Efficacy of Implementing Seasonal Malaria Chemoprevention in Karamoja Region, Uganda
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Sulfadoxine pyrimethamine and amodiaquine|DRUG: dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Three Different Doses of an Anti SARS-CoV-2 Hyperimmune Equine Serum in COVID-19 Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Anti SARS-CoV-2 equine hyperimmune serum|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microfracture vs. Microfracture and BMAC for Osteochondral Lesions of the Talus
Status: UNKNOWN
Conditions: Osteochondral Lesion of Talus
Interventions: PROCEDURE: Microfracture with Bone Marrow Aspirate Concentrate|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Idelalisib in Combination With Ofatumumab for Previously Treated Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Idelalisib|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-retainer Lithium Di-silicate Versus Zirconia Resin Bonded Bridge for Replacement of an Anterior Missing Tooth.
Status: RECRUITING
Conditions: Missing Teeth
Interventions: OTHER: Single-retainer Lithium Di-silicate Resin Bonded Fixed Partial Denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a 2-session Parent Training Programme for Caregivers of Younger Children in Zimbabwe
Status: NOT_YET_RECRUITING
Conditions: Child Maltreatment
Interventions: BEHAVIORAL: Tabudira Parenting Intervention for Early Childhood Development|OTHER: Nutritional guide for younger children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complementary Self-help Strategies for Patients With Post-COVID-19 Syndrome
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome
Interventions: BEHAVIORAL: Complementary self-help strategies in addition to treatment as usual|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Lidocaine Gel Decrease Pain Perception in Women Undergoing Diagnostic Flexible Cystoscopy
Status: UNKNOWN
Conditions: Cystoscopy|Lidocaine|Pain Perception
Interventions: DRUG: lidocaine gel|DRUG: Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Programme in Workplaces in Hong Kong (Phase Ⅴ)
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: General health talk|BEHAVIORAL: Personalized chat-based interactions|BEHAVIORAL: Text message|BEHAVIORAL: Phone follow-up/counselling service|DRUG: Mailed nicotine replacement therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Vulvar Intraepithelial Neoplasia Grade 2|Vulvar Intraepithelial Neoplasia Grade 3
Interventions: DRUG: VTD-101 ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granzyme B PET Imaging Drug as a Predictor of Immunotherapy Response to Checkpoint Inhibitors
Status: RECRUITING
Conditions: Solid Tumor, Unspecified, Adult|Lymphoma
Interventions: DRUG: Single Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Bacillus Subtilis DE111® on Daily Bowel Movements
Status: COMPLETED
Conditions: Bowel Movement Regulation|Occasional Constipation|Occasional Diarrhea
Interventions: DIETARY_SUPPLEMENT: Bacillus subtilis DE111®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of the Effectiveness of Seroquel XR and Seroquel XR Plus Lithium in Patients With Acute Bipolar Mania: An Open-label, Randomized, Parallel Groups, Rater-blinded, 4 Week, Multicenter, Comparative,Study
Status: TERMINATED
Conditions: Acute Bipolar Mania
Interventions: DRUG: Quetiapine fumarate|DRUG: lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients.
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Placebo|DRUG: Sodium Zirconium Cyclosilicate (ZS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study Analyzing RNA Expression Of Endometrial Biopsy Samples From Placebo, Bazedoxifene/Conjugated Estrogens And Raloxifene
Status: TERMINATED
Conditions: Postmenopause
Interventions: DRUG: Bazedoxifene 10 mg/CE 0.625 mg|DRUG: Bazedoxifene 20 mg/CE 0.625 mg|DRUG: Bazedoxifene 40 mg/CE 0.625 mg|DRUG: Bazedoxifene 10 mg/CE 0.45 mg|DRUG: Bazedoxifene 20 mg/CE 0.45 mg|DRUG: Bazedoxifene 40 mg/CE 0.45 mg|DRUG: Raloxifene 60 mg|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of High-intensity Training Compared to Resistance Training in Cancer Patients Undergoing Radiotherapy
Status: COMPLETED
Conditions: Prostate Cancer|Head and Neck Cancer|Rectum Cancer
Interventions: BEHAVIORAL: High-intensity interval training|BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Ankle Arthrodesis Versus Open Reduction and Internal Fixation for Fragility Fractures Around the Ankle in the Frail Elderly.
Status: RECRUITING
Conditions: Ankle Fractures|Pilon Fracture
Interventions: PROCEDURE: Primary ankle arthrodesis (fusion)|PROCEDURE: ORIF (open reduction and internal fixation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics
Status: COMPLETED
Conditions: Alcoholism
Interventions: PROCEDURE: Bronchoscopy|DIETARY_SUPPLEMENT: Zinc sulfate 220 mg once daily|DIETARY_SUPPLEMENT: S-adenosylmethionine 400 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cervical Ripening and Labor Induction Using Misoprostol With or Without Intravaginal Isosorbide Mononitrate
Status: COMPLETED
Conditions: Cervical Ripening
Interventions: DRUG: Misoprostol with or without isosorbide mononitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Information Technology to Improve Bedtime Media Use in Children
Status: TERMINATED
Conditions: Sleep Hygiene, Inadequate
Interventions: OTHER: Problematic bedtime media use counseling|OTHER: Sleep problem counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Sonifilan on the Quality of Life in Patients With Cervical Cancer During Radiation or Chemoradiation Therapy
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Sonifilan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study Evaluating the Contribution of Rheopheresis in the Treatment of Uremic Calciphylaxis (RHEO-CUA)
Status: COMPLETED
Conditions: Rheopheresis|Calcifying Uremic Arteriolopathy|Uremic Calciphylaxis
Interventions: PROCEDURE: Rheopheresis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expression and Function of the Renin-Angiotensin System in the Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DRUG: Candesartan|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remimazolam and Endovascular Procedures of Cerebrovascular Diseases
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Anesthesia
Interventions: DRUG: remimazolam|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternate Day vs. Daily Iron Supplementation in Iron Depleted Women in the Philippines
Status: TERMINATED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: daily ferrous sulfate|DIETARY_SUPPLEMENT: alternate day ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved Complete Clinical Response After Neoadjuvant Chemoradiotherapy
Status: TERMINATED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Rectal resection|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation Study for Optimization of Anemia MAnagement in Hemodialysis Patients With End Stage Kidney Disease Using the Dialysis Anemia TReatmenT Model
Status: ACTIVE_NOT_RECRUITING
Conditions: Dialysis
Interventions: PROCEDURE: Algorithm model-based Aranesp doses|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GM-CT-01 Plus 5-Fluorouracil as Third- or Fourth-Line Therapy for Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: GM-CT-01 plus 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AL-37807 Ophthalmic Suspension, 1.0%|DRUG: Latanoprost, 0.005% (Xalatan)|OTHER: AL-37807 Vehicle|DRUG: Timolol Maleate Ophthalmic Gel Forming Solution, 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sub Lingual Misoprostol Before IUD Insertion in Women With Only Previous Cesarean Section
Status: COMPLETED
Conditions: IUD Insertion
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures
Status: COMPLETED
Conditions: Chronic Anal Fissures
Interventions: DRUG: VEN 307|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Capacity of the MRI Spectroscopy to Define the Tumor Area Enriched in Glioblastoma Stem Cells. Proof of Concept Study
Status: COMPLETED
Conditions: Glioblastoma
Interventions: PROCEDURE: Surgery (based on preoperative multimodal MRI) followed by the standard radio-chemotherapy stupp protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis
Status: RECRUITING
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: OATD-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment-Resistant Minimal Change Disease (TR-MCD), and Diabetic Nephropathy (DN)
Status: TERMINATED
Conditions: Glomerulosclerosis, Focal Segmental|Minimal Change Disease|Diabetic Nephropathies
Interventions: OTHER: FSGS/TR-MCD|OTHER: Diabetic Nephropathy (DN)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TI
Status: COMPLETED
Conditions: Osteoporosis|Thalassemia Major|Thalassemia Intermedia
Interventions: DRUG: Neridronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in India
Status: COMPLETED
Conditions: Lymphedema|Lymphatic Filariasis|Filariasis
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Radium-223 and VEGF-Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma and Bone Mets
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Pazopanib|DRUG: Sorafenib|DRUG: Radium-223
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: AB801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of the EndoArt™ for Treatment of Subjects Suffering From Corneal Edema
Status: COMPLETED
Conditions: Chronic Cornel Edema
Interventions: DEVICE: EndoArt® Artificial Endothelial Layer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Trans-foraminal Lumbar Epidural Injection of Dexmedetomidine Against Magnesium Sulfate When Combined With Dexamethasone in Uni-lateral Lower Limb Radicular Pain. Multi-centeric Comparative Study
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: epidural transforaminal injection of magnesuim sulfate|DRUG: epidural transforaminal injection of dexmedtemodine|DRUG: transforaminal epidural injection of dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous In-line Filter in Patient Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: SIRS
Interventions: DEVICE: In-line filtration|DEVICE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer Metastatic|Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax
Status: RECRUITING
Conditions: Stage 4 NSCLC|Radiotherapy
Interventions: RADIATION: Prophylactic Palliative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Importance of Electrical Stimulation as a Treatment for Urinary Incontinence in Patients Prostatectomy
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: electrostimulation with exercises MAPs|OTHER: exercises MAPs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: three kinds of antibiotics including amoxicillin，tetracycline, furazolidone, levofloxacin,clarithromycin,levofloxacin,tinidazole,metronidazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting.
Status: RECRUITING
Conditions: Saphenectomy|No Touch|Coronary Artery Disease|Cardiovascular Diseases|Wound Complication
Interventions: PROCEDURE: Conventional Saphenous vein harvest|PROCEDURE: No touch Saphenous vein harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Treatment A: BGF MDI HFO|DRUG: Treatment B: BGF MDI HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT