pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ESPB Versus PVPB Regarding Their Effect on Peri-operative Opioid Consumption in Patients Undergoing Minimally Invasive Mitral Valve Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: ERAS|Post Operative Pain
Interventions: PROCEDURE: Thoracic erector spinae plane block|PROCEDURE: Thoracic paravertebral plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Development of a Clinical Screening, Diagnostic and Evaluation Tool for Patients With Lower Limb Lymphedema: Aim 1
Status: RECRUITING
Conditions: Lower Limb Lymphedema
Interventions: DIAGNOSTIC_TEST: Assessor A (first measurement): measurement methods and questionnaires for the assessment of LLL|DIAGNOSTIC_TEST: Assessor B: measurement methods and questionnaires for the assessment of LLL|DIAGNOSTIC_TEST: Assessor A (second measurement: measurement methods and questionnaires for the assessment of LLL|DIAGNOSTIC_TEST: Assessor A (2 weeks later): measurement methods and questionnaires for the assessment of LLL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Driving Pressure Limited Ventilation During Video-assisted Thoracoscopic Lobectomy
Status: UNKNOWN
Conditions: Pulmonary Complication|Thoracic Surgery
Interventions: PROCEDURE: Protective ventilation 1|PROCEDURE: Protective ventilation 2|PROCEDURE: Driving Pressure Limited Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Air Filtration on Asthmatic Children
Status: UNKNOWN
Conditions: Asthma in Children
Interventions: DEVICE: Bedroom air filtered by an air filtration device to remove airborne pollutants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: REOLYSIN|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit
Status: UNKNOWN
Conditions: Alcohol Withdrawal|Alcohol Withdrawal Delirium
Interventions: DRUG: Phenobarbital|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Tislelizumab and Radiotherapy in Newly Diagnosed Extranodal NK/T-cell Lymphoma, Nasal Type
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Kala: Virtual Bharatanatyam Wellness Program for Students
Status: COMPLETED
Conditions: Quality of Life|Cultural Competence|Stress
Interventions: BEHAVIORAL: A 4-week Bharatanatyam course from the organization Mindful Kala
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Ambispective Cohort Study of Orelabrutinib in Combination With Standard Treatment Regimen for Untreated DLBCL
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse Neoplasms by Histologic Type
Interventions: DRUG: Orelabrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: AC regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-gel Versus Air-Q LMA for Pediatric Patients
Status: COMPLETED
Conditions: Easy Insertion, Complications Ans Suitability of i Gel and Air Q LMA
Interventions: OTHER: LMA i gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: COPE - COVID-19 in Pregnancy and Early Childhood
Status: ACTIVE_NOT_RECRUITING
Conditions: Sars-CoV2|Covid-19|Pregnancy Complications|Pregnancy Preterm|Pregnancy in Diabetic|Neonatal Infection
Interventions: OTHER: biological samples, questionnaires and interviews
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Clinical Trial of NPI-0052 in Patients With Advanced Solid Tumor Malignancies or Refractory Lymphoma
Status: COMPLETED
Conditions: Cancer|Lymphomas
Interventions: DRUG: NPI-0052
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
Status: COMPLETED
Conditions: Coenzyme Q10|Oxidative Stress|Aging
Interventions: DIETARY_SUPPLEMENT: Administration of a product with Fitosomed Ubiquinone|PROCEDURE: Coenzyme Q10 level in muscle biopsies|DIAGNOSTIC_TEST: Coenzyme Q10 level in plasma, blood cells, urine cells|DIAGNOSTIC_TEST: Total antioxidant capacity after strenous exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Pharmacokinetic Study|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise During Chemotherapy for Patients With Hematological Malignancies
Status: UNKNOWN
Conditions: Hematological Diseases|Hematological Malignancies
Interventions: OTHER: Aerobic exercise|BEHAVIORAL: Fatigue counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of a Uridine Supplement on HIV Infected Adults With Lipoatrophy
Status: COMPLETED
Conditions: HIV Infections|Lipoatrophy
Interventions: DRUG: NucleomaxX|DRUG: NucleomaxX placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of Peginterferon Lambda for 48 Weeks in Patients With Chronic HDV
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis Delta Virus
Interventions: DRUG: Peginterferon Lambda-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab in Combination With Ramucirumab for the Treatment of Advanced Hepatocellular Carcinoma That Has Failed at Systemic Therapy
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma That Has Failed at Systemic Therapy
Interventions: DRUG: Cadonilimab Injection|DRUG: Ramucirumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the Synchrony Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: Standard Monofocal Intraocular Lens|DEVICE: Synchrony® Dual Optic Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
Status: RECRUITING
Conditions: Aortoiliac Occlusive Disease|Peripheral Arterial Disease
Interventions: DEVICE: Stenting of the Common and/or External Iliac Arteries with the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis|DEVICE: Stenting of the Common and/or External Iliac Arteries with Bare Metal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)
Status: RECRUITING
Conditions: Recurrent or Metastatic Solid Tumors
Interventions: DRUG: Ifinatamab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Chemosensory-Based Orbitofrontal Cortex (CBOT) for Opioid Use Disorder
Status: UNKNOWN
Conditions: Opioid Use Disorder, Moderate|Opioid Use Disorder, Severe|Withdrawal Symptoms|Craving|Negative Affectivity
Interventions: DRUG: CBOT + TAU|DRUG: Sham + TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PES After Soft Tissue Augmentation Using CTG Around Immediate Dental Implants Versus Immediate Dental Implants Alone in Esthetic Zone
Status: COMPLETED
Conditions: Soft Tissue Augmentation
Interventions: PROCEDURE: connective tissue graft|DEVICE: immediate implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating PD-0299685 for the Treatment of Vasomotor Symptoms (Hot Flashes / Flushes) Associated With Menopause
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: PD-0299685
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autophagy in Paediatric Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease|Pediatric Crohns Disease
Interventions: OTHER: Blood samples|OTHER: Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: In Vitro Effects of Procyanidine on Semen Parameter and DFI
Status: COMPLETED
Conditions: Spermatogenesis and Semen Disorders|DNA Double Strand Break
Interventions: DIETARY_SUPPLEMENT: procyanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Aponeurectomy on the 2-year Recurrence Rate of Dupuytren's Disease
Status: RECRUITING
Conditions: Dupuytren's Disease
Interventions: PROCEDURE: Aponeurectomy with grafting|PROCEDURE: Aponeurectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Therapeutic Recreation Activities on Aberrant Behaviours of Individuals With Intellectual Disabilities
Status: COMPLETED
Conditions: Therapeutic Recreation|Intellectual Disability|Recreational Activities|Aberrant Behaviors
Interventions: BEHAVIORAL: Therapeutic Recreation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Extension Study to Evaluate Safety & Tolerability of QR-421a in Subjects With Retinitis Pigmentosa
Status: TERMINATED
Conditions: Retinitis Pigmentosa|Usher Syndrome Type 2
Interventions: DRUG: RNA antisense oligonucleotide for intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone and Metformin in Diabetic Children
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study of Dapoxetine Concomitantly Administered in Participants Taking Terazosin
Status: COMPLETED
Conditions: Ejaculation
Interventions: DRUG: Treatment sequence 2|DRUG: Treatment sequence 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengthening Circadian Signals
Status: RECRUITING
Conditions: Improving Cardiometabolic Outcomes in Adults
Interventions: DIETARY_SUPPLEMENT: Melatonin 1 mg|DIETARY_SUPPLEMENT: Placebos|OTHER: Meal Timing|OTHER: NON Meal Timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Parental Enteral Nutrition on Quality Of Parent-Child Interactions
Status: ENROLLING_BY_INVITATION
Conditions: Premature|Parent-Child Relations
Interventions: OTHER: parent-pushed enteral feeding|OTHER: syringe-push enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: PS-341 in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia in Blast Phase, or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Adult Acute Promyelocytic Leukemia (M3)|Blastic Phase Chronic Myelogenous Leukemia|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Relapsing Chronic Myelogenous Leukemia
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-bundle Versus Single-Bundle Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: ACL Injury
Interventions: PROCEDURE: ACL reconstruction: Double bundle|PROCEDURE: ACL reconstruction: Single bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colesevelam Versus Placebo in the Treatment of Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Colesevelam Hcl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Oral CAB|DRUG: Oral TDF/FTC|DRUG: Placebo for oral CAB|DRUG: Placebo for oral TDF/FTC|DRUG: CAB LA|DRUG: Placebo for CAB LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)
Status: RECRUITING
Conditions: Leukemia, B-Cell
Interventions: GENETIC: Autologous TRICAR-ALL T-cells and lymphodepletion chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Pioglitazone and Glimepiride on the Rate of Progression of Atherosclerotic Disease.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: DFMO|DRUG: Celecoxib|DRUG: Cyclophosphamide|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma
Status: RECRUITING
Conditions: Salivary Gland Neoplasm Duct
Interventions: DRUG: Rezvilutamide|DRUG: Leuprolide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.
Status: COMPLETED
Conditions: Intestinal Obstruction
Interventions: DRUG: Loperamide placebo|DRUG: Loperamide|DEVICE: Colon Transit|DRUG: Sulfasalazine|DRUG: Placebo of MNTX and NLX|DRUG: Naloxone|DRUG: Methylnaltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Opioid Analgesia in Sickle Cell
Status: WITHDRAWN
Conditions: Sickle Cell Disease
Interventions: DRUG: Dextromethorphan|DRUG: Codeine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protocol for Alpha MSH Infusion Study in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: α-MSH infusion|OTHER: Placebo solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Transcutaneous Electric Nerve Stimulation on Primary Dysmenorrhea-a Randomized Control Study
Status: COMPLETED
Conditions: Primary Dysmenorrhea,
Interventions: DEVICE: Transcutaneous Electric Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of KITE-197 in Participants With Relapsed or Refractory Large B-cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Large B-cell Lymphoma
Interventions: DRUG: KITE-197|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation With New Class of Osteoplastic Materials
Status: COMPLETED
Conditions: Tooth Extraction|Atrophy of Edentulous Alveolar Ridge
Interventions: DEVICE: Octacalcium phosphate|DEVICE: Bio-Oss|DEVICE: Tricalcium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Effectiveness of Activation Mist on Facial Skin Wrinkles
Status: UNKNOWN
Conditions: Skin Wrinkles on Face and Neck Areas
Interventions: OTHER: Activation Mist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Presence of Circulating Cluster of Differentiation 4 Positive 28 Null T Helper Lymphocytes(CD4+CD28-) in Patients With Autoimmune Hemolytic Anemia.
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Hemolytic Anemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of URGOBD001 Compression System
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Venous compression system of the lower limbs stage C6 / C6r of the CEAP classification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer With Elevated Serum CA125 Were Compared With Those Who Did Not Receive Neoadjuvant Chemotherapy.
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Feasibility and Aesthetic Outcomes of Benelli Technique for Nipple Sparing Mastectomy in Surgical Treatment of Grade 3 and 4 Gynecomastia
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Managment of Gynecomastia
Interventions: OTHER: Benelli technique for nipple sparing mastectomy in surgical treatment of grade 3 and 4 gynecomastia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dan-shen Extract On Lipoprotein Associated PHospholipase A2 Levels IN Patients With Stable Angina Pectoris
Status: UNKNOWN
Conditions: Angina, Stable|Inflammation
Interventions: DRUG: Dan-shen extract|DRUG: Placebo|OTHER: Standard medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping Technique Versus Virtual Reality in Patients With Chronic Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Impingement Syndrome, Shoulder
Interventions: OTHER: Kinsiotaping|OTHER: Motion-controlled VR games|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effects of Seretide® Evohaler and a Generic Salmeterol/Fluticasone Hydrofluoroalkane (HFA) Pressurized Metered-dose Inhaler (pMDI) on Functional Respiratory Imaging Parameters in Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: RADIATION: Functional Respiratory Imaging|DRUG: Salmeterol xinafoate and Fluticasone propionate HFA pMDI|DRUG: Seretide Evohaler|DRUG: Placebo of Test product|DRUG: Placebo of Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Labor Induction With Dinoprostone in Oppose to Cervical Ripening Balloon as a Factor of BMI.
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DRUG: Dinoprostone|DEVICE: Double lumen cervical ripening balloon.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Feeding in Infants With Duct Dependant Lesions.
Status: NOT_YET_RECRUITING
Conditions: Duct Dependent Lesions|Necrotising Enterocolitis|Death|Growth
Interventions: OTHER: enteral feeding as per predefined protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Intra-articular Injection of Mesenchymal Stem Cells in Knee Joint Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: mesenchymal stem cell|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of OMS201 in Subjects Undergoing Ureteroscopic Treatment for Removal of Urinary Tract-Located Stones
Status: COMPLETED
Conditions: Urinary Calculi|Urinary Stones|Urinary Tract Stones
Interventions: DRUG: OMS201|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibodies and Liver Retransplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplant Failure|Antibody-mediated Rejection
Interventions: DIAGNOSTIC_TEST: Luminex-based solid phase assay of banked sera for anti-HLA antibodies directed against the donor of a second liver transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracoronary Stenting and Restenosis - Randomized Trial of Drug-eluting Stent Implantation or Drug-coated Balloon Angioplasty According to Neointima Morphology in Drug-eluting Stent Restenosis 5
Status: RECRUITING
Conditions: Coronary Artery Disease|Restenoses, Coronary
Interventions: DEVICE: Drug eluting stent (DES)|DEVICE: Drug coated ballloon (DCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Poly-L-lactic Acid
Status: COMPLETED
Conditions: Buttock Contouring|Buttock Lifting
Interventions: DEVICE: Poly-L-lactic acid (Sculptra® Aesthetic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen With or Without Octreotide in Treating Postmenopausal Women With Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: octreotide acetate|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Mobile Apps & FitBit v. Usual Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Gastric Cancer|Hepatic Cancer|Colon Cancer|Rectal Cancer|Small Bowel Cancer
Interventions: OTHER: Mobile health application and Fitbit + standard of care|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exercises Directed To Dynamic Stiffness Of The Thoracolumbar Region And Performance Of Amateur Runners
Status: RECRUITING
Conditions: Fascia
Interventions: OTHER: Group Experimental/Fascial Fitness|OTHER: Group Sham/Static stretching exercise|OTHER: Control Group/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Immunogenicity and Safety of a Pandemic Avian Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: recombinant influenza hemagglutinin|BIOLOGICAL: Advax1|BIOLOGICAL: Advax2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventing Alcohol Withdrawal With Oral Baclofen
Status: TERMINATED
Conditions: Alcoholism|Alcohol Withdrawal
Interventions: DRUG: Baclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Follow-up of Sanfilippo Type A Patients Treated by Intracerebral SAF-301 Gene Therapy
Status: COMPLETED
Conditions: Mucopolysaccharidosis Type III A|Sanfilippo Disease Type A
Interventions: GENETIC: SAF-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: multisite HD-tDCS EMG-driven robot hand|DEVICE: Sham HD-tDCS EMG-driven robot hand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication
Status: UNKNOWN
Conditions: Carbon Monoxide-induced Parkinsonism
Interventions: RADIATION: 18F-FP-(+)-DTBZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Micropulse Laser for Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy|Age-related Macular Degeneration
Interventions: PROCEDURE: Micropulse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Level Up! Adaptive Gaming for Children With Upper Limb Differences
Status: RECRUITING
Conditions: Upper Limb Amputation at the Wrist|Pediatric|Upper Limb Amputation|Upper Limb Amputation at the Hand|Amniotic Band Syndrome|Upper Limb Amputation Below Elbow (Injury)
Interventions: DEVICE: One Handed Video Game Controller Adapter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: a Prospective Trial Comparing Robot-assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Renal Malignant Tumor|Renal Cyst|Renal Tumor
Interventions: PROCEDURE: partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate Safety and Tolerability of Ranibizumab in Macular Edema Secondary to Retinal Vein Occlusion (Cohort 2)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.045: NANT Merkel Cell Carcinoma (MCC) Vaccine: Combination Immunotherapy in Subjects With MCC Who Have Progressed on or After PD-L1 Therapy
Status: WITHDRAWN
Conditions: Merkel Cell Carcinoma
Interventions: BIOLOGICAL: Avelumab|BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: 5-fluorouracil|DRUG: Leucovorin|DRUG: nab-Paclitaxel|DRUG: omega-3-acid ethyl esters|RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
Status: RECRUITING
Conditions: Dental Implant|Bone Loss
Interventions: BIOLOGICAL: Allograft particles hydrated with rhPDGF|BIOLOGICAL: Allograft particles hydrated in a conventional way with saline.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Cutaneous and Ocular Local Tolerance of Two Cosmetic Facial Cleanser in Healthy Females With Sensitive Skin
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Micellar cleanser|OTHER: Micellar foaming cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Emphysema|COPD|Severe Emphysema
Interventions: DEVICE: AeriSeal|DEVICE: Zephyr Valves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disease and Biomarker Profiling of Chinese Lupus Nephritis
Status: NOT_YET_RECRUITING
Conditions: Characterize the Molecular Profile of Lupus Nephritis(LN) Patients to Understand Themechanism(s)Contributing to Patient Responsiveness to Soc|Integrated Analysis of LN Patient Molecular Profiling and Clinical Annotations to Understand LNdisease Heterogeneity for Disease Endotype|Validate the Association of the Candidate Biomarker Panel Proposed in Table 3-1 With LN Diseasemonitoring
Interventions: OTHER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: Isotretinoin|DRUG: Procarbazine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hemostatic Efficacy of the HemCon Dental Dressing in a Population Treated With Anticoagulant Medications
Status: WITHDRAWN
Conditions: Tooth Extractions
Interventions: DEVICE: HemCon Dental Dressing|DEVICE: Gauze with pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Anti LewisY Chimeric Antigen Receptor in Myeloma, Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: UNKNOWN
Conditions: Multiple Myeloma|Acute Myeloid Leukaemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Anti-LeY- scFv-CD28-ζ vector,.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PATH-2: Platelet Rich Plasma in Achilles Tendon Healing
Status: COMPLETED
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: PRP Injection into Achilles tendon rupture gap|PROCEDURE: Imitation Injection into Achilles tendon rupture gap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Triplanar Rotary Resistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Association of Hand Hygiene Practice on Primary Schoolgirls Absence Due to URIs in Riyadh City, 2017-2018.
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: OTHER: Hand Hygiene Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Compare Fentanyl Nasal Spray With Intravenous Opioids to Treat Severe Pain
Status: COMPLETED
Conditions: Advanced Cancers|Pain
Interventions: DRUG: Fentanyl Nasal Spray|DRUG: Hydromorphone Hydrochloride|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: [68Ga]Ga-NOTA-SNA002 (PD-L1 PET Tracer) for PET/CT in Patients With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Positron-Emission Tomography(PET)
Interventions: BIOLOGICAL: [68Ga]Ga-NOTA-SNA002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Lens A (comfilcon A lens)|DEVICE: Lens B (lehfilcon A lens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme|Gliosarcoma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Glioma
Interventions: DRUG: enzyme-inducing anti-epileptic drugs|DRUG: enzyme-inducing anti-epileptic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Herpes Zoster Vaccine With Various Formulations in Adults >= 50 Years
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes zoster vaccine GSK1437173A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Upper Trapezius Stretching in Patients With Cervical Spondylosis
Status: RECRUITING
Conditions: Cervical Spondylosis
Interventions: OTHER: Upper fibers of trapezius stretching|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Y90 Radioembolization in HCC Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Pembrolizumab|DEVICE: Y90 radioembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: rituximab [Mabthera/Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine for the Prevention of Cardiovascular Events in Myocardial Infarction Patients - a Safety Pilot Trial
Status: COMPLETED
Conditions: Myocardial Infarction|Acute Coronary Syndrome|Inflammation|Hydroxychloroquine|Antirheumatic Agents|Cardiovascular Diseases
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1316/Placebo in Combination With Chemotherapy in Patients With Resectable NSCLC
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: SHR-1316、Paclitaxel (Albumin Bound)、Carboplatin|DRUG: SHR-1316、Chemotherapeutic|DRUG: Placebo、Chemotherapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation Comparing a PTFE Nonresorbable Membrane to a Collagen Membrane
Status: COMPLETED
Conditions: Clinical Efficacy
Interventions: PROCEDURE: PTFE membrane|PROCEDURE: Collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Favipiravir and Ribavirin Formulation for Treatment of COVID-19
Status: UNKNOWN
Conditions: SARS-CoV2|COVID-19
Interventions: DRUG: Ribavirin Capsules|DRUG: Favipiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESOLUTE ONYX Post-Approval Study (Bifurcation Cohort)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Development and Evaluation of the Healthy Beat Accupunch (HBA) Exercise Program for the Community Older Adults
Status: COMPLETED
Conditions: Functional Fitness
Interventions: OTHER: Healthy Beat Accupunch exercise program|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coronary Artery Disease (CAD) in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Women|Stable Angina Pectoris
Interventions: PROCEDURE: stress-echocardiography|PROCEDURE: stress-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: the Effect of Weight Bearing Status on Healing and Pain Outcomes After Surgery for Osteochondral Defects of the Ankle
Status: COMPLETED
Conditions: Osteochondritis Dissecans of Ankle and Joints of Foot
Interventions: OTHER: Weight-Bearing as Tolerated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Gastric Emptying and Glycemic Variability in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Erythromycin lactobionate|DRUG: Placebo IV|DRUG: [13C]-Spirulina|DRUG: Erythromycin Ethylsuccinate Suspension|DRUG: Placebo Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Evaluation of the Fixed Combination Brimonidine Tartrate 0.2%/ Timolol Maleate 0.5% to Latanoprost 0.005% in Glaucoma or Ocular Hypertension Subjects
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: fixed combination of brimonidine tartrate 0.2% timolol maleate 0.5% ophthalmic solution|DRUG: latanoprost 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression
Status: RECRUITING
Conditions: Depression, Unipolar|Fall
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Fall Prevention|OTHER: Telephone support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pulsed Electromagnetic Field Therapy on Acute Radiodermatitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Dermatitis, Radiation Induced
Interventions: OTHER: Pulsed electromagnetic field|OTHER: traditional skin care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Concentrating Endogenous Stromal Cells in the Fat Graft Using TGI Device
Status: COMPLETED
Conditions: Facial Injuries|Tissue Injury
Interventions: DEVICE: Tissue Genesis Cell Isolation System™ (TGI CIS)|PROCEDURE: Standard of care fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Cardiopulmonary Bypass|Tetralogy of Fallot
Interventions: DRUG: Dexmedetomidine Hcl 100 Mcg/mL Inj|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: PDR001|DRUG: bevacizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Immunogenicity of a Chikungunya Virus Vaccine Candidate (VLA1553) in Healthy Volunteers
Status: COMPLETED
Conditions: Chikungunya
Interventions: BIOLOGICAL: VLA1553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: User Preference/Validation Evaluation of the New Philips Respironics Positive Airway Pressure Application
Status: COMPLETED
Conditions: Sleep Disordered Breathing
Interventions: OTHER: Standard of Care|DEVICE: DreamMapper Application|DEVICE: DreamMapper Application with Therapist Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-inflammatory Effects Glycopyrronium
Status: COMPLETED
Conditions: Asthma|Allergic Asthma
Interventions: DRUG: QVM149|DRUG: QMF149
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cannabis on Simulated and Actual Driving in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Cannabis|OTHER: tobacco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH