pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Optimizing Body Composition for Function in Older Adults
Status: COMPLETED
Conditions: Obesity|Overweight With Indications for Weight Loss
Interventions: DRUG: Pioglitazone|BEHAVIORAL: Resistance exercise training to maximize muscle power|BEHAVIORAL: Hypocaloric diet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integrating Hepatitis C Screening With Dried Blood Spot Testing Into Colorectal Cancer Screening
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: BEHAVIORAL: Screening HCV attached onto CCR screening|BEHAVIORAL: Screening HCV attached onto CCR screening by self-testing|BEHAVIORAL: Screening HCV at primary care center
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Treatment Study of CDP870 Self-injection in Patients With Active Rheumatoid Arthritis Who Are Participating in the Long-term Treatment Studies (Study 275-08-002 or Study 275-08-004) of CDP870
Status: COMPLETED
Conditions: Active Rheumatoid Arthritis
Interventions: DRUG: CDP870
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Viaskin Peanut to Treat Peanut Allergy
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Viaskin Peanut 250 mcg|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Reuterin D3 drops|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Bevacizumab After First-Line Chemotherapy and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Eccentric Exercise and Static Stretching on Muscle Flexibility
Status: NOT_YET_RECRUITING
Conditions: Muscle Stretching Exercise|Range of Motion, Articular
Interventions: OTHER: Nordic Hamstring Eccentric Exercise Training|OTHER: Passive Hamstring Static Stretching Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure in Improving Constipation Among Inpatients in Neurology Departments
Status: COMPLETED
Conditions: Constipation
Interventions: PROCEDURE: Acupressure|PROCEDURE: routine nursing and fake acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot|Educational Intervention|Foot Care|Foot Ulcer, Diabetic|Foot Cellulitis
Interventions: BEHAVIORAL: Self-care behavior to promote foot care through educational guidance among individual with diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study of Immunization in People Living With HIV Undergoing an ATI for Elicitation of VRC01-lineage Antibodies
Status: RECRUITING
Conditions: Chronic HIV Infection
Interventions: BIOLOGICAL: 426c.Mod.Core-C4b|OTHER: Adjuvant 3M-052-AF+Alum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CHF6563 in Babies With Neonatal Opioid Withdrawal Syndrome
Status: TERMINATED
Conditions: Neonatal Opioid Withdrawal Syndrome
Interventions: DRUG: CHF6563|DRUG: Morphine|DRUG: CHF6563 matched placebo|DRUG: Morphine matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Palbociclib With Exemestane Plus GnRH Versus Capecitabine in Premenopausal Women With HR+ MBC
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Exemestane|DRUG: Leuprolide Acetate|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Endothelin-1 in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: Ambrisentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Normative Database for Gait Analysis on the GRAIL UZ Gent
Status: RECRUITING
Conditions: Gait
Interventions: OTHER: Walking on an instrumented treadmill|OTHER: Walking on an instrumented treadmill while dual-tasking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aging and Estrogen on Cortical Function
Status: COMPLETED
Conditions: Memory Loss|Cognitive Changes|Postmenopausal Symptoms
Interventions: DRUG: Estradiol oral capsule|DRUG: transderman estrogen patch|DRUG: trasdermal placebo patch|DRUG: placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Alternative Approach to Fatigue and Comfort Levels in Hemodialysis Patients: Reiki Energy Therapy.
Status: RECRUITING
Conditions: Hemodialysis
Interventions: BEHAVIORAL: Reiki Energy Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of 100% Orange Juice on Food Intake and Glycemic Response in Adults
Status: COMPLETED
Conditions: Healthy|Adult|Glycemic Response|Appetite
Interventions: OTHER: Orange juice|OTHER: Orange flavoured drink|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mesylate Apatinib for Stage Ⅳ STS After Failure of Chemotherapy
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma, Adult, Stage II
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of GreenGene™ F to Previously Treated Patients With Severe Hemophilia A
Status: UNKNOWN
Conditions: Hemophilia A
Interventions: BIOLOGICAL: GreenGene™ F and an approved recombinant Factor VIII product|BIOLOGICAL: GreenGene™ F|BIOLOGICAL: GreenGene™ F|BIOLOGICAL: GreenGene™ F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Oral Sulfate Tablet(ORA·FANGⓇ)|DRUG: Sodium Picosulfate Solution(PicosolutionⓇ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study With a Loading Dose of Clofazimine in Adult Patients With Nontuberculous Mycobacterial Disease
Status: COMPLETED
Conditions: Nontuberculous Mycobacterial Diseases
Interventions: DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: thiotepa|DRUG: vincristine sulfate|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Combined Impact of Intermittent Preventive Treatment and Insecticide Treated Bednets in Reducing Morbidity From Malaria in African Children
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Intermittent preventive treatment with AQ+ SP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Toxicity of Topically Applied Nepafenac 0.3% vs Ketorolac 0.5%
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: nepafenac 0.3%|DRUG: ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: JAB-30355|DRUG: JAB-30355
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Parecoxib Sodium Intravenous Patient-controlled Analgesia in Laparotomic Liver Resection
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: conventional intravenous infusion pump|DRUG: parecoxib|PROCEDURE: intravenous infusion pump of patient-controlled analgesia|DRUG: fentanyl citrate+ ondansetron hydrochloride + normal saline|DRUG: celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Risk Screening Nutritional Support Gastrointestinal Cancer
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: DIETARY_SUPPLEMENT: Malnutrition five-step treatment model + conventional nutritional intervention|OTHER: Conventional nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Tirzepatide|DRUG: Mibavademab|DRUG: Tirzepatide-Placebo|DRUG: Mibavademab-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RandOmized Study Exploring the Combination of radioTherapy With Two Types of Acupuncture Treatment: The ROSETTA Trial
Status: UNKNOWN
Conditions: Cancer
Interventions: RADIATION: Radiotherapy|DEVICE: Needle Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain Inflammation and Cannabis in HIV
Status: COMPLETED
Conditions: HIV Infections|Neuropathic Pain|Cannabis
Interventions: OTHER: Receipt of Coupon for Placebo Soft-Gel Capsule|OTHER: Receipt of Coupon for High THC Soft-Gel Capsule|OTHER: Receipt of Coupon for Equal THC and CBD Soft-Gel Capsule|OTHER: Receipt of Coupon for High CBD Soft-Gel Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Using Intragen Fractional Radiofrequency With NeuViVa for the Treatment of Vaginal Laxity and Urogynecology Symptoms.
Status: UNKNOWN
Conditions: Vaginal Laxity|Urinary Incontinence|Sexual Dysfunction
Interventions: DEVICE: Intragen fractional radiofrequency with NeuViVa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: vadadustat|DRUG: Rifampin|DRUG: Probenecid|DRUG: Cyclosporins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea
Status: COMPLETED
Conditions: Irregular Astigmatism
Interventions: PROCEDURE: photorefractive keratectomy (PRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology-Supported Physical Activity Intervention for Metastatic Breast Cancer Survivors: Fit2ThriveMB
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Obesity
Interventions: BEHAVIORAL: Fit2ThriveMB App|BEHAVIORAL: Fitbit|BEHAVIORAL: Physical Activity Coaching Calls|BEHAVIORAL: Healthy Living Coaching Calls|BEHAVIORAL: Cancer.net app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Group-Based Telehealth Music Therapy Intervention for Patients With Dementia: A Pilot Study
Status: COMPLETED
Conditions: Behavioral and Psychiatric Symptoms of Dementia|Alzheimer Disease|Lewy Body Disease|Frontotemporal Dementia
Interventions: BEHAVIORAL: Music therapy intervention|BEHAVIORAL: Personalized music CD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study on the Efficacy and Safety of E3810 in Patients With Non-erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Non-erosive Gastroesophageal Reflux Disease
Interventions: DRUG: E3810|DRUG: E3810|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19
Status: COMPLETED
Conditions: COVID
Interventions: DRUG: Ivermectin|DRUG: Azithromycin|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Bisoprolol|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD6474 Phase IIa Dose Finding Multicentre Study
Status: COMPLETED
Conditions: Non Small Cell Lung Carcinoma
Interventions: DRUG: ZD6474 (vandetanib) 100mg|DRUG: ZD6474 (vandetanib) 200mg|DRUG: ZD6474 (vandetanib) 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Physical Performance of Women at Different Stages of the Menstrual Cycle, and Photobiomodulation Therapy
Status: COMPLETED
Conditions: Menstrual Cycle Disorder
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: WVE-120102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bracing for Walking in Parkinson's Disease
Status: COMPLETED
Conditions: Gait Disorders, Neurologic|Parkinson Disease
Interventions: DEVICE: Carbon Fiber Ankle Foot Orthosis (AFO)|OTHER: Standardized walking/exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nighttime Macronutrient Choice and Combined Resistance and High-intensity Interval Training
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Whey Protein|OTHER: Combined Resistance and High-Intensity Interval training|OTHER: Casein Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Smoking and Alcohol Cessation Intervention in Bladder Cancer Surgery Patients
Status: COMPLETED
Conditions: Bladder Cancer|Smoking|Alcohol Consumption
Interventions: BEHAVIORAL: Educational programme for smoking and alcohol cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of the Efficacy and Stability of a Wearable ECG Monitor
Status: NOT_YET_RECRUITING
Conditions: Arrhythmias, Cardiac|Bradycardia|Tachycardia|Atrial Fibrillation|Atrial Flutter|Ventricular Premature Complexes
Interventions: DEVICE: ECG monitoring by telemetry device and patch-type ECG monitor at the same time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Contraceptive Hormones, Immunity, and Microbiome Evaluation
Status: RECRUITING
Conditions: Hormonal Contraception
Interventions: DRUG: Depot medroxyprogesterone acetate (DMPA)|DRUG: Etonogestrel implant (Eng-Implant)|DRUG: Levonorgestrel IUD (Lng-IUD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tamoxifen Therapy for Myotubular Myopathy
Status: RECRUITING
Conditions: X Linked Myotubular Myopathy
Interventions: DRUG: ApoTamox 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Trial Evaluating the Efficacy and Safety of Ciprofol Injection for the Induction of Sedation/Anesthesia in Subjects Undergoing Gynecological Outpatient Surgeries
Status: COMPLETED
Conditions: Gynecological Outpatient Surgery
Interventions: DRUG: Ciprofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Study of New Medications to Treat Vaginal Infections
Status: COMPLETED
Conditions: Vaginal Infection
Interventions: DRUG: Terconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease
Status: COMPLETED
Conditions: Mild CognitIve Impairment|Alzheimer's Disease
Interventions: OTHER: Aerobic exercise|OTHER: Stretch exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander
Status: COMPLETED
Conditions: Pain, Postoperative|Mammaplasty
Interventions: DRUG: Depofoam bupivacaine|DRUG: Bupivacaine hydrochloride (HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Training in Patients With Advanced Lung Cancer - A Pilot Study
Status: TERMINATED
Conditions: Advanced (Stage IV) Non-small Cell Lung Cancer (NSCLC)
Interventions: BEHAVIORAL: biofeedback-mediated stress management (BFSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Building Emotional Self-Awareness Teletherapy (BEST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Concussion, Mild|Concussion, Brain|Concussion, Severe|Concussion, Intermediate|Concussion; Syndrome|Concussion Injury of Cerebrum|Concussion With Brief Loss of Consciousness|Alexithymia
Interventions: BEHAVIORAL: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Electrical and Magnetic Neuromodulation in Persons With Chronic Spinal
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries|Spinal Cord Diseases
Interventions: DEVICE: RISES-T System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CALR Exon 9 Mutant Peptide Vaccine to Patients With CALR-mutant Myeloproliferative Neoplasms
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm, Unclassifiable|Essential Thrombocythemia|Myelofibrosis
Interventions: BIOLOGICAL: CALRLong36 peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dipyridamole/Magnesium To Improve Sickle Cell Hydration
Status: WITHDRAWN
Conditions: Anemia, Sickle Cell
Interventions: DRUG: oral dipyridamole, oral magnesium, or a combination of both
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Targeted Biopsy or Standard Biopsy for Clinical Significant Prostate Cancer Detection
Status: UNKNOWN
Conditions: Prostate Neoplasm
Interventions: PROCEDURE: Targeted prostate biopsy|PROCEDURE: Standard biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: SMART-DAPPER: Leveraging the Depression And Primary-care Partnership for Effectiveness-implementation Research Project
Status: COMPLETED
Conditions: Depression, Unipolar|Posttraumatic Stress Disorder|Trauma
Interventions: DRUG: Fluoxetine|BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MT-3534 Clinical Pharmacology Study in Healthy Adult Male Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Adult Male Volunteers
Interventions: BIOLOGICAL: MT-3534|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）
Status: RECRUITING
Conditions: Ischemic Stroke, Acute|TIA|Symptomatic Intracranial Artery Stenosis
Interventions: DRUG: Tirofiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study Between 400 mg LX4211 Tablets and 2 X 200 mg LX4211 Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LX4211|DRUG: LX4211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol for Prophylaxis of Morphine Induced Pruritis in Caesarean Section
Status: NOT_YET_RECRUITING
Conditions: Pruritus Caused by Drug
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Standard Medical Management in Secondary Prevention of Ischemic Stroke in China
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Aspirin / Clopidogrel, Atorvastatin / Simvastatin|DRUG: Asprin / Clopidogrel, Atorvastatin / Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: tDCS to Increase Aerobic Performance in Runners
Status: COMPLETED
Conditions: Athletic Performance
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Harmonic ACE®+7 Shears in Laparoscopic Colectomy
Status: COMPLETED
Conditions: Benign or Malignant Disease Indicated for Colectomy
Interventions: DEVICE: Harmonic ACE®+7 Shears
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects During Exercise in Patients With Pulmonary Hypertension Receiving Sildenafil
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: OTHER: Hemodynamic effect of exercise under Sildenafil|OTHER: Hemodynamic effect of exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Uterine Peristaltic Wave Frequencies Between Pregnant and Non-pregnant Women in Embryo Transfer Cycles
Status: COMPLETED
Conditions: Uterine Peristaltic Frequencies Between Pregnant and Non-pregnant Women in Embryo Transfer Cycles
Interventions: DIAGNOSTIC_TEST: 3DTVUS : Uterine peristaltic frequencies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Effectiveness of a Novel Portable Non-Pneumatic Active Compression Device vs. an Advanced Pneumatic Compression Device for Treating Lower Extremity Lymphedema
Status: COMPLETED
Conditions: Lymphedema|Lymphedema of Leg|Chronic Venous Insufficiency|Venous Insufficiency|Lymphedema, Lower Limb
Interventions: DEVICE: Cross over Device (PCD or Dayspring - alternate to first group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic-enriched Artichoke in Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei IMPC 2.1 LMGP22043|DIETARY_SUPPLEMENT: Ordinary artichokes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Hand Exercise Game on Grip Strength and Vascular Maturation
Status: NOT_YET_RECRUITING
Conditions: Muscle Weakness|Angiogenesis
Interventions: BEHAVIORAL: Interactive Hand Exercise Game|BEHAVIORAL: Soft ball exercise ( routine care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of the VEGFR-FGFR-PDGFR Inhibitor, Lucitanib, Given to Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Breast Cancer|MBC|HER2 Positive|HER2|Estrogen Receptor Positive|ER|Triple Negative
Interventions: DRUG: Lucitanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Persistence of Oral Tolerance to Peanut
Status: COMPLETED
Conditions: Eczema|Egg Allergy|Food Allergy|Hypersensitivity
Interventions: OTHER: Avoidance of peanut
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Comparing Taxotere® Cisplatin and 5-Fluorouracil (TPF) With Standard Cisplatin and 5-Fluorouracil (PF) Followed by Chemoradiation in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: XRP6976 (Docetaxel/Taxotere)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory AML or MDS
Status: COMPLETED
Conditions: AML|MDS
Interventions: DRUG: CYC065|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Atorvastatin on the Nitric Oxide-system in Healthy Young Man
Status: COMPLETED
Conditions: Cardiovascular Diseases|Nephropathy
Interventions: DRUG: Placebo|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Defect, Congenital Heart|Heart Septal Defects, Ventricular|Heart Septal Defects, Atrial|Endocardial Cushion Defects
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Aflibercept Versus Ranibizumab in Management of Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Aflibercept|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of HVT and Bowen Technique in Patients of SI Joint Dysfunction With Upslipped Innominates
Status: ACTIVE_NOT_RECRUITING
Conditions: Joint Diseases
Interventions: DIAGNOSTIC_TEST: High Velocity Thrust|OTHER: Bowen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
Status: RECRUITING
Conditions: Addiction|Opioid Use|Substance Use Disorders|Opioid Use Disorder
Interventions: DRUG: Placebo|DRUG: Auvelity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prucalopride Succinate on Gastrointestinal Motility After Laparoscopic Gastrectomy : Prospective Double Blind Case-control Study
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Arm I : Experimental (Prucalopride succinate group)|DRUG: Arm II : Control (Mosapride citrate group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab|DRUG: oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)
Status: COMPLETED
Conditions: Kennedy's Disease|Spinal and Bulbar Muscular Atrophy
Interventions: DRUG: Dutasteride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: Human umbilical cord tissue-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Patient-Reported Outcomes To Improve the Care of People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Anxiety|Depression|Patient Satisfaction
Interventions: OTHER: Intensive Use of Patient Reported Outcome Measures and Open PROM Availability to Treating Neurologist|OTHER: Conservative Use of Patient Reported Outcome Measures and Blinded PROM Availability to Treating Neurologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating The Efficacy Of A Novel Ibuprofen Formulation On Fever In Patients With An Uncomplicated Acute Infection
Status: TERMINATED
Conditions: Infection
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tolerance, Satiation and Sensory Acceptance of Yogurts Containing Dietary Fiber and Coffee Cascara Extract
Status: COMPLETED
Conditions: Satiation|Gastrointestinal Tolerance|Organoleptic Appreciation
Interventions: OTHER: Dietary fiber|OTHER: Control yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outlook: An Intervention to Improve Quality of Life in Serious Illness
Status: COMPLETED
Conditions: Neoplasms|Pulmonary Disease, Chronic Obstructive|Heart Failure|Renal Disease
Interventions: OTHER: Outlook Attention Control|OTHER: Outlook Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Salmonella Conjugates CVD 2000: Study of Responses to Vaccination With Trivalent Salmonella Conjugate Vaccine to Prevent Invasive Salmonella Disease
Status: COMPLETED
Conditions: Risk Reduction
Interventions: BIOLOGICAL: Trivalent Salmonella Conjugate Vaccine (TSCV) Full-Strength Formulation|BIOLOGICAL: Trivalent Salmonella Conjugate Vaccine (TSCV) Half-Strength Formulation|BIOLOGICAL: Trivalent Salmonella Conjugate Vaccine (TSCV) Dilutional Half-Strength Formulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supplementary Implants Supporting Conventional Removable Dental Prosthesis (RDPs) in Kennedy Class I
Status: RECRUITING
Conditions: Partial Edentulism Kennedy Class 1
Interventions: DEVICE: dental implants and retentive implant components|DEVICE: dental implants and supportive implant components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
Status: COMPLETED
Conditions: Autism|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Growth Factor on Implant Osseointegration
Status: COMPLETED
Conditions: Bone Loss, Alveolar|Resorption, Bone|Osseointegration Failure of Dental Implant
Interventions: PROCEDURE: Concentrated growth factor(CGF)|PROCEDURE: Advanced platelet rich fibrin (A-PRF)|PROCEDURE: Control side of concentrated growth factor study group|PROCEDURE: Control side of advanced platelet rich fibrin study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-risk Populations in Uganda, Africa
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: FTC/TDF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Scar Formation in Syndactyly Release Surgery With Full Thickness Skin Graft Versus Skin Graft Substitute
Status: COMPLETED
Conditions: Syndactyly
Interventions: DEVICE: Hyalomatrix|OTHER: Skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Food Preservative Propionic Acid in Post-prandial Metabolism
Status: UNKNOWN
Conditions: Obesity|Insulin Resistance|Diabetes
Interventions: DIETARY_SUPPLEMENT: Calcium propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxygen Reserve Index to Reduce Hyperoxia
Status: COMPLETED
Conditions: Hyperoxemia
Interventions: PROCEDURE: Titration of fraction of inspired oxygen (FiO2) guided by SpO2|PROCEDURE: Titration of fraction of inspired oxygen (FiO2) guided by ORI and SpO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study To Find The Best Doses Of SU011248 And Gemcitabine When Given Together To Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: SU011248; Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Reinforcement of the Staple Line in Left Pancreatectomy Reduce the Rate of Pancreatic Fistula?
Status: UNKNOWN
Conditions: Post Operative Pancreatic Fistula
Interventions: DEVICE: Surgisis (C-SLRA-ECH60) made by COOK Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Automated Closed-Loop Versus Restrictive Fluid Therapy in Abdominal Surgery
Status: COMPLETED
Conditions: Abdominal Laparoscopic and/or Robotic Surgery
Interventions: DEVICE: Closed-Loop GDFT|OTHER: Restrictive Fluid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity
Status: RECRUITING
Conditions: Histamine|Cowhage|Sleep Fragmentation
Interventions: OTHER: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Patient Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest With Successful Resuscitation
Interventions: OTHER: Decision Aid for Surrogate Decision Makers of Comatose Survivors of Cardiac Arrest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children
Status: COMPLETED
Conditions: Chronic Renal Failure|Peritoneal Membrane Disorder
Interventions: DRUG: lactate and bicarbonate buffered dialysis solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliadelic Treatment to Reduce Psychological Distress in Persons With Inoperable Pancreatobiliary Cancer
Status: RECRUITING
Conditions: Pancreas Cancer|Biliary Tract Cancer|Psychological Distress
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Diabetes Screening Immediately Postpartum (DIP)
Status: RECRUITING
Conditions: Pre-Gestational Diabetes|Type2diabetes|Pregnancy in Diabetic|Pregnancy, High Risk|Gestational Diabetes|Gestational Diabetes Mellitus in the Puerperium
Interventions: DIAGNOSTIC_TEST: Immediate inpatient postpartum OGTT|DIAGNOSTIC_TEST: Standard of care 4-12 week postpartum OGTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: GSK2981278 ointment|DRUG: Vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IISART (International Industry Society of Advanced Rehabilitation Technology) Advanced Rehabilitation Technology Study
Status: RECRUITING
Conditions: Neurologic Disorder
Interventions: DEVICE: Tyromotion, Fourier Intelligence, Thera-Trainer, EKSO Bionics|OTHER: Standard inpatient rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure With Acceptance-Based Versus Habituation-Based Rationale for Public Speaking Anxiety
Status: COMPLETED
Conditions: Public Speaking|Social Fear
Interventions: BEHAVIORAL: Exposure w/ Acceptance-Based Rationale|BEHAVIORAL: Exposure w/ Habituation-Based Rationale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of an Adapted and Supported Water Polo Program to Reduce Fatigue Related to Cancer and Improve Psychological and Social Recovery in Patients With Breast Cancer Remission
Status: UNKNOWN
Conditions: Cancer Related Fatigue|Breast Cancer
Interventions: OTHER: accompanied and adapted water polo program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Lederfolin|DRUG: 5-Fluorouracil|RADIATION: Short-course radiotherapy|PROCEDURE: TME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incentives for Internet-based Adherence to SMBG for Teens With T1D
Status: COMPLETED
Conditions: Contingent Versus Noncontingent Incentives
Interventions: BEHAVIORAL: Internet-delivered, Incentive-based intervention + Motivational Interviewing|BEHAVIORAL: Internet-delivered, non-contingent incentives + Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Protein Hydrolysate on Muscle Strength Recovery
Status: COMPLETED
Conditions: Muscle Strength Recovery
Interventions: DIETARY_SUPPLEMENT: Protein hydrolysate high dose|DIETARY_SUPPLEMENT: Protein hydrolysate low dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixovex-1 Single Agent and Combination Therapy
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor|Head and Neck Cancer
Interventions: BIOLOGICAL: Ixovex-1|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preferences for Open Vs. Endovascular Repair for Abdominal Aortic Aneurysm
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm
Interventions: OTHER: Decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of DPD for Predicting Efficacy and Safety to S-1 Plus Oxaliplatin in Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Gastrointestinal Cancer
Interventions: DRUG: S-1 plus oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Sertraline to Treat Children With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: Sertraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis, Coronary|Myocardial Ischemia|Ischemic Heart Disease|Acute Coronary Syndrome|Angina Pectoris
Interventions: DEVICE: Orsiro DES|DEVICE: Xience DES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Wafer and Ulnar Shortening in Ulnar Abutment
Status: UNKNOWN
Conditions: Wrist Impaction
Interventions: PROCEDURE: wafer procedure|PROCEDURE: arthroscopy and ulnar shortening osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT