pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Improving Cognition and Behavior in Pediatric Cancer Survivors Using a Novel Mindful Attention Training
Status: RECRUITING
Conditions: Pediatric Cancer
Interventions: BEHAVIORAL: Adaptive Attention Training|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maxillary Sinus Augmentation With Xenogeneic Bone Graft Associated or Not With Fibrin Rich in Platelets and Leukocytes Produced by Horizontal Centrifugation: A Randomized Clinical Trial.
Status: COMPLETED
Conditions: Platelet-rich Fibrin|Sinus Floor Augmentation|Cone-beam Computed Tomography|Dental Implants|Bone Substitutes|Maxillary Sinus|Atrophic Maxilla
Interventions: PROCEDURE: Maxilar Sinus augmentation|PROCEDURE: Dental implant placement using guided surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: comfilcon A MTO|DEVICE: comfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
Status: RECRUITING
Conditions: Tourette Syndrome|Persistent Tic Disorder
Interventions: OTHER: CBIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders
Status: COMPLETED
Conditions: Substance Abuse
Interventions: BEHAVIORAL: Therapeutic Education System (TES)|BEHAVIORAL: Treatment-as-Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cocoa Flavanol on the BOLD Response and Cognitive Function in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: cocoa flavanol supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Endocrine Therapy Duration on Clinical Outcome of Patients With HR+ Intraductal Carcinoma of the Breast
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Toremifene|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Epilepsy|Asthma|Shame|Self-Compassion|Stress|Perfectionistic Cognitions
Interventions: OTHER: Online self-compassion intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma
Status: COMPLETED
Conditions: Severe Uncontrolled Asthma
Interventions: DRUG: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Abdominal Catgut Embedding Combined With Auricular Acupressure Therapy for Obese Patients
Status: COMPLETED
Conditions: Acupuncture
Interventions: OTHER: Catgut Embedding at acupoints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Raltegravir in HIV/HCV Co-infected Patients
Status: WITHDRAWN
Conditions: HIV|Hepatitis C
Interventions: DRUG: raltegravir|DRUG: Atazanavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gland Expression on the Regeneration of Meibomian Gland
Status: NOT_YET_RECRUITING
Conditions: Meibomian Gland Dysfunction
Interventions: PROCEDURE: Meibomian gland expression (MGX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adoptive Transfer of Specific HCC Antigens CD8+ T Cells for Treating Patients With Relapsed/Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: HCC antigens-specific CD8+ T lymphocytes|DRUG: IL-2|DRUG: Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of GSK233705 in Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Digital Health Application for Multiple Sclerosis (Levidex)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: levidex|BEHAVIORAL: Control|OTHER: treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Dasatinib as a Potential Targeted Treatment in Cancers With DDR2 Genetic Changes (MATCH-Subprotocol X)
Status: WITHDRAWN
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Plasma Cell Myeloma
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZILRETTA in Subjects With Glenohumeral Osteoarthritis
Status: RECRUITING
Conditions: Glenohumeral Osteoarthritis
Interventions: DRUG: ZILRETTA|DRUG: TCA-IR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Versus (vs.) Intravenous Administration of Daratumumab in Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Dara SC|DRUG: Dara IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT)
Status: RECRUITING
Conditions: High-risk MDS
Interventions: DRUG: Azacitidine|DRUG: Standard Chemotherapy|PROCEDURE: Allogeneic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (Bicalutamide) Casodex vs Placebo in Non-metastatic Early Prostate Cancer
Status: COMPLETED
Conditions: Non-Metastatic Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab-Based Therapy for the Treatment of Newly Diagnosed Multiple Myeloma With Kidney Failure
Status: TERMINATED
Conditions: Plasma Cell Myeloma|Renal Failure
Interventions: DRUG: Bortezomib|BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reducing Sedentary Behaviour in Comparison to Promoting Physical Activity on Chronic Non-specific Low Back Pain in a Sedentary Population
Status: TERMINATED
Conditions: Chronic Low-back Pain|Sedentary Behavior
Interventions: BEHAVIORAL: Reducing sedentary behaviour|BEHAVIORAL: Increase physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MiracleFeet Foot Abduction Brace Sensor Trial
Status: UNKNOWN
Conditions: Clubfoot|Telemedicine|Patient Compliance
Interventions: DEVICE: Steenbeek Foot Abduction Brace (SFAB)|DEVICE: MiracleFeet Foot Abduction Brace (mFAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Menopause|Perimenopause
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of HIP1802 to HGP1705 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: HIP1802|DRUG: HGP1705
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Population-Wide Effectiveness of U.S. Tobacco Cessation Quitlines
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: DRUG: Nicotine patch|DRUG: Nicotine gum|BEHAVIORAL: CMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation With or With Transcatheter Arterial Embolization for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: PROCEDURE: Radiofrequency ablation|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study in Preschool Children Aged 4-5 Years With Attention-deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Placebo|DRUG: SPD489 (Lisdexamfetamine dimesylate)|DRUG: SPD489
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopic gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccine With Imiquimod for Patients With Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: BIOLOGICAL: Dendritic Cell Vaccine in combination with Imiquimod cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinically Isolated Syndrome|Relapsing Remitting Multiple Sclerosis
Interventions: BEHAVIORAL: Therapeutic diet and lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
Status: RECRUITING
Conditions: Toothbrushing|Gingivitis|Cleft Lip and Palate
Interventions: DEVICE: Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Efficacy of Drug-coated Balloon Versus Drug-eluting Stent in Large de Novo Coronary Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease|Drug-coated Balloon
Interventions: DEVICE: Drug-Coated Balloon|DEVICE: Sirolimus-Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teneteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events-III
Status: COMPLETED
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: tenecteplase (0.25 mg/kg, Max 25 mg)|DRUG: standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of Retigabine vs. Placebo in Post-Herpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Retigabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Virtual Reality Exposure Therapy to Prolonged Exposure
Status: COMPLETED
Conditions: Stress Disorders|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure Therapy (PE)|BEHAVIORAL: Virtual Reality Exposure Therapy (VRET)|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-005)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Surotomycin|DRUG: Vancomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods of Adjusting the Mechanical In-Exsuflation in Neuromuscular Adult Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuromuscular Diseases
Interventions: OTHER: Objective adjustment of the MI/E exsuflation pressure and evaluation of cough effort|OTHER: Subjective adjustment of the MI/E exsuflation pressure and evaluation of cough effort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: Glucagon|DRUG: Glucagon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Marginal, Internal Adaptation and Clinical Performance of Endo-crowns Fabricated From Nano Hybrid and Lithium Di-silicate Ceramic Materials.
Status: UNKNOWN
Conditions: Clinical Fit and Clinical Performance
Interventions: PROCEDURE: Nano-ceramic hybrid (Grandio Blocs) Endo-crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine Supplementation and Short-term Mortality in Covid-19
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Standard enteral nutrition|COMBINATION_PRODUCT: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Immunogenicity and Safety of an Investigational Influenza Vaccine in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK investigational vaccine GSK1557482A|BIOLOGICAL: Fluzone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Naso-Esophageal Tube Feeding in Patients With High Cervical Spinal Cord Injury.
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury Cervical
Interventions: DEVICE: Naso-Esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding|BEHAVIORAL: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Compare Efficacy Nebulized and Intravenous Magnesium Sulphate in Thai Children
Status: UNKNOWN
Conditions: Acute Severe Asthma
Interventions: DRUG: isotonic magnesium sulphate|DRUG: 50% magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorder|Bipolar Disorder|Schizo Affective Disorder-Bipolar Type
Interventions: DRUG: Placebo|DIETARY_SUPPLEMENT: Citicoline|DRUG: Pregnenolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the COVID-19 Public Health Crisis on the Mental Health and Physical Well-Being of Cancer Patients, the Coping With COVID Study
Status: COMPLETED
Conditions: COVID-19 Infection|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against Infection
Status: RECRUITING
Conditions: Neutropenic Fever
Interventions: DRUG: Meropenem Injection|DRUG: Levofloxacin|DRUG: Amoxicillin Clavulanate|DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Efficacy, Toxicity, Harvest Yield and Quality of Life
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Doxil|DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Normal Tension Glaucoma
Interventions: DRUG: brimonidine tartrate/timolol malate Ophthalmic Solution|DRUG: bimatoprost ophthalmic solution 0.01%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Digestibility of Serum-Derived Bovine Immunoglobulin Protein Isolate in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Serum-derived bovine immunoglobulin protein isolate (SBI)|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: LOXO-783|DRUG: Fulvestrant|DRUG: Imlunestrant|DRUG: Abemaciclib|DRUG: Anastrozole, Exemestane, or Letrozole|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent to Adult Patient-centered HIV Transition (ADAPT) Study
Status: COMPLETED
Conditions: HIV|AIDS
Interventions: OTHER: PEPFAR Enhanced Standard of Care (PESCA)|BEHAVIORAL: Peer Transition Advocate (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Addition to Morphine in Patients With Metastatic Cancer
Status: COMPLETED
Conditions: Refractory Pain|Metastatic Cancer
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Pancreatic Cancer|Colorectal Cancer|Prostate Cancer|Breast Cancer|Ovarian Cancer|Loss of Appetite|Fatigue|Cachexia|Anorexia
Interventions: DRUG: PF-06946860|DRUG: Placebo for PF-06946860
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents
Status: COMPLETED
Conditions: Polypharmacy|Inappropriate Prescribing
Interventions: OTHER: Individual Deprescribing Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cessation Preferences of Menthol Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Non-flavored 2mg nicotine gum|OTHER: Non-flavored 4mg nicotine gum|OTHER: Mint-flavored 2mg nicotine gum|OTHER: Mint-flavored 4mg nicotine gum|OTHER: Non-flavored nicotine inhaler|OTHER: Mint-flavored nicotine ihaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gemtuzumab Ozogamicin in Induction and Glasdegib in Postremission Therapy in Patients With AML (Acute Myeloid Leukemia)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin 147|DRUG: Gemtuzumab Ozogamicin 1|DRUG: Glasdegib|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Ketamine on Chronic Pain After Mastectomy
Status: SUSPENDED
Conditions: Chronic Pain
Interventions: DRUG: Saline|DRUG: Ketamine 0.5mg/kg|DRUG: Ketamine 0.75mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Airway Stimulation Versus Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: upper airway stimulation|DEVICE: continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Pregabalin and Continuous Wound Infusion for Pain Control Following Thoracotomy
Status: COMPLETED
Conditions: Post-thoracotomy Pain
Interventions: DRUG: Pregabalin and normal saline infusion, PRG|DRUG: Pregabalin and ropivacaine 02% infusion|DRUG: Placebo drug, normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E-learning on the Trainees' Ability to Diagnose and Treat Acute Otitis Media Among Children
Status: COMPLETED
Conditions: Ear Infection
Interventions: OTHER: e-learning teaching module|OTHER: Standard teaching method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Jaw Reconstruction With Printed Titanium and Free Tissue Transfer
Status: UNKNOWN
Conditions: Neoplasm, Oral|Osteoradionecrosis of Jaw|Mandibular Diseases|Jaw Cancer|Jaw Diseases|Surgery
Interventions: PROCEDURE: Mandibular reconstruction with free tissue transfer.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanical Insufflator-exsufflator to Control Mucus Hypersecretion in Patients in Palliative Care - A Feasibility Study
Status: UNKNOWN
Conditions: Palliative Care|Mucus Hypersecretion
Interventions: DEVICE: Mechanical Insufflation-Exsufflation|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Intravenous Immunoglobulin-associated Adverse Reactions
Status: COMPLETED
Conditions: Immunoglobulin Therapy
Interventions: DEVICE: Infusomat filter (Codan Duofilter-Set V86-P)|DEVICE: IVIG application without filter (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study on the Effectiveness of a Lacticaseibacillus Strain on Blood Cholesterol Levels
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholesterol Levels
Interventions: OTHER: Lacticaseibacillus with oats|OTHER: Plain oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Motexafin Gadolinium (MGd) in Combination With Docetaxel and Cisplatin for Treatment of Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma|Carcinoma, Bronchogenic
Interventions: DRUG: Motexafin Gadolinium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation Versus Clinical Hypnosis for Acute, Experimental Pain
Status: COMPLETED
Conditions: Mindfulness Meditation|Clinical Hypnosis
Interventions: BEHAVIORAL: Mindfulness meditation|BEHAVIORAL: Clinical hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HoLEP vs mTURP in Management of Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: PROCEDURE: Holmium laser enucleation of prostate|PROCEDURE: monopolar transurethral resection of prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pharmacokinetics of Dipyridamole in Asasantin Extended Release (ER) and in a Combination of Persantin Immediate Release Tablets and ASA Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asasantin (ER)|DRUG: Persantin|DRUG: Acetyl salicylic acid (ASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Common Bile Duct Stones
Status: UNKNOWN
Conditions: Common Bile Duct Stone
Interventions: PROCEDURE: LC + LCBDE + ENBD + primary closure of CBD|PROCEDURE: ERCP technique + LC|PROCEDURE: LC + LCBDE + primary closure of CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Mastectomy
Status: TERMINATED
Conditions: Mastectomy
Interventions: DEVICE: Scalpel and Traditional Electrosurgery|DEVICE: PEAK PlasmaBlade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remimazolam and Propofol on Postoperative Delirium
Status: RECRUITING
Conditions: Hip Fractures|Knee Osteoarthritis|Femur Fracture
Interventions: DRUG: Remimazolam (Byfavo)|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers
Status: RECRUITING
Conditions: Marginal Ulcer
Interventions: DRUG: Omeprazole 40 milligrams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Rivaroxaban in Japanese Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Embolism, Atrial Fibrillation and Venous Thrombosis
Interventions: DRUG: Rivaroxaban (BAY 59-7939)|DRUG: Rivaroxaban (Xarelto, BAY 59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers
Status: COMPLETED
Conditions: Tobacco Use Cessation|Smoking Cessation|Smoking|Tobacco Use Disorder
Interventions: OTHER: AD + Integrated Tobacco Order Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose-Derived Adult Stromal Vascular Cell Transplantation for Alopecia
Status: UNKNOWN
Conditions: Hair Loss/Baldness|Alopecia
Interventions: PROCEDURE: Lipoaspiration|PROCEDURE: Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus
Status: WITHDRAWN
Conditions: Living Donor Kidney Transplants Patients
Interventions: DRUG: Tacrolimus, Myfortic and Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Oral OP-1250 in Combination With Palbociclib in HR+/HER2- Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Palazestrant|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Metastatic Cancer|Pain|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D|DRUG: zoledronic acid|DRUG: Sm-153|RADIATION: Sr-89
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induced Pluripotent Stem Cell Derived Exosomes Nasal Drops for the Treatment of Refractory Focal Epilepsy
Status: RECRUITING
Conditions: Refractory Focal Epilepsy
Interventions: DRUG: iPSC-Exos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Finding Better Treatment of Bronchiolitis: A Clinical Trial of Oral Nitazoxanide for the Treatment of Bronchiolitis in Infants Presenting to Hospital Emergency Departments
Status: WITHDRAWN
Conditions: Bronchiolitis
Interventions: DRUG: Nitazoxanide|DRUG: Placebo (for Nitazoxanide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Light Therapy and Chronic Neck and Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Neck Pain|Musculoskeletal Pain|Musculoskeletal Strain|Musculoskeletal Sprain
Interventions: DEVICE: Erchonia PL2000|DEVICE: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy
Status: COMPLETED
Conditions: Internal Carotid Artery Stenosis
Interventions: PROCEDURE: sonolysis|PROCEDURE: endarterectomy|PROCEDURE: carotid stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Pads With Cold Solution of Magnesium Sulfate or Cold Water Postpartum Perineal Pain and Healing
Status: RECRUITING
Conditions: Women After Delivery With Perineal Pain
Interventions: DRUG: Magnesium sulfate 33% solution|OTHER: Cold water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: DRUG: Intravenous immunoglobulin [ImmunoRel™ (batch 20081217)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
Status: RECRUITING
Conditions: Hydrocephalus, Normal Pressure|Hydrocephalus
Interventions: DEVICE: eShunt Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Effect on Cognitive and Psychiatric Dysfunction in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Treatment Resistant Disorders
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Macronutrient Composition on Glucose Dynamics in Persons With Type 1 Diabetes
Status: COMPLETED
Conditions: type1diabetes
Interventions: OTHER: 7-day diet|OTHER: 7-day diet|OTHER: 7-day diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
Status: COMPLETED
Conditions: Malaria|Pregnant|HIV
Interventions: DRUG: Sulphadoxine-pyrimethamine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trans-pedal Access for Endovascular Revascularization in Complex Infra-popliteal Lesions in Critically Ischemic Limb
Status: COMPLETED
Conditions: Critical Lower Limb Ischemia
Interventions: PROCEDURE: Trans-pedal access for endovascular revascularization in complex infra-popliteal lesions in critically ischemic limb
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)
Status: COMPLETED
Conditions: Overweight|Obesity|Type 2 Diabetes|Prediabetes
Interventions: BEHAVIORAL: Weight loss diet|BEHAVIORAL: Weight loss diet plus exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Square Step Exercise Applied by Telerehabilitation in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: COPD|Cognitive Impairment|Balance; Distorted
Interventions: OTHER: The Square-Step Exercise Training|OTHER: Strengthening Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: WHC+ (Women's Health CoOp PLUS)
Status: COMPLETED
Conditions: HIV|Sexual Risk|Sexually Transmitted Diseases|Substance Abuse|Violence|Victimization
Interventions: BEHAVIORAL: Test, Treat, Retain(TTR) + Women's Health CoOp (WHC)|BIOLOGICAL: Test, Treat, Retain(TTR) only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PAP Systems External Clinical Studies (ECS)
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: PAP System A (with Amalfi) then PAP System B (with CLA11)|DEVICE: PAP System B (with CLA11) then PAP System A (with Amalfi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacology Study of TS-142 in Patients With Obstructive Sleep Apnea Hypopnea.
Status: COMPLETED
Conditions: Patients With Mild Obstructive Sleep Apnea Hypopnea
Interventions: DRUG: TS-142|DRUG: Dose-matched Placebo to TS-142
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Ketoacidosis, Diabetic|Hyperglycaemia (Diabetic)|Hypoglycemia
Interventions: DEVICE: The SHINE SYSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Transcranial Direct Current Stimulation With Proprioceptive Training in Blind People
Status: UNKNOWN
Conditions: Blindness, Acquired|Blindness Congenital
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|OTHER: Dynamic proprioceptive exercises|OTHER: static proprioceptive exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Anaesthesia in Cutaneous Head and Neck Surgery
Status: COMPLETED
Conditions: Pain, Acute|Head and Neck Cancer|Cutaneous Tumor
Interventions: DRUG: EMLA|DRUG: Ethyl chloride|DRUG: Aqueous cream BP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of FB1001 in Patients
Status: NOT_YET_RECRUITING
Conditions: Optic Neuropathy|NAION - Non-Arteritic Ischemic Optic Neuropathy|APAC - Acute Primary Angle Closure|Glaucoma, Angle-Closure
Interventions: DRUG: FB1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acupressure Therapy on Patient With Depression
Status: UNKNOWN
Conditions: Depressive Disorder|Depressive Disorder, Major|Depressive Symptoms
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Codeine on Pharyngeal and Esophageal Motility
Status: COMPLETED
Conditions: Esophageal Motility Disorders
Interventions: DRUG: Codeine Phosphate|DRUG: Siripus simplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Comparing the Safety and Efficacy of Two Doses of BC-3781 vs Vancomycin in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
Status: COMPLETED
Conditions: Bacterial Infections|Infection
Interventions: DRUG: BC-3781|DRUG: BC-3781|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Caffeine on Cardiac Arrhythmias
Status: COMPLETED
Conditions: Supraventricular Tachycardia (SVT)|Atrial Fibrillation
Interventions: DRUG: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PSIQS Study - User Experience With Pro-Set
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: MiniMed® Pro-set®|DEVICE: MiniMed® Quick-set®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical vs Oral Metronidazole After Benign Anorectal Surgery
Status: COMPLETED
Conditions: Hemorrhoids|Anal Fissure|Anal Fistula
Interventions: DRUG: Topical metronidazole|DRUG: oral metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Versus Surgery Alone for Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Neoplasm
Interventions: DRUG: cisplatin and paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scapulo-Thoracic Mobilization Compared to IASTM in Patients With Mechanical Neck Pain
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: OTHER: scapulothoracic mobilization|OTHER: IASTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds
Status: TERMINATED
Conditions: Superficial Surgical Site Infection
Interventions: DEVICE: Collatamp Gentamicin Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy
Status: COMPLETED
Conditions: Radiculopathy
Interventions: DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of a Novel Niclosamide Solution in Combination With Camostat
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Niclosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study of Non-surgical Treatment and Exercise Rehabilitation in Patients With Anterior Cruciate Ligament Rupture
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture|Osteoarthritis, Knee
Interventions: PROCEDURE: non surgical treatment|PROCEDURE: surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Full Thickness Resection Versus Standard Therapy of the Colorectal Neoplasia
Status: UNKNOWN
Conditions: Polyps|Colon Cancer
Interventions: DEVICE: EMR and ESD|DEVICE: Over- the- scope full- thickness resection device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Tolerance Study After Ocular Administration of Tiotropium in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 0.02 mcg tiotropium solution|DRUG: 0.04 mcg tiotropium solution|DRUG: 0.08 mcg tiotropium solution|DRUG: 0.16 mcg tiotropium solution|DRUG: 0.28 mcg tiotropium solution|DRUG: 0.40 mcg tiotropium solution|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Trauma Symptoms in the Aftermath of Sexual Abuse in Children and Adolescents in Burundi
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Mental Health Issue|Family Dynamics
Interventions: BEHAVIORAL: Preventive Narrative Exposure Therapy (PreNET) family intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)
Status: RECRUITING
Conditions: IBS|Ulcerative Colitis, Active|Ulcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms)|Healthy Controls|Crohn's Disease, Active|Crohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)
Interventions: OTHER: Sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSH-12)
Status: COMPLETED
Conditions: Wounds
Interventions: DRUG: Oleogel-S10, non-adhesive wound dressing|DEVICE: Non-adhesive wound dressing only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tramadol Addiction On Dental Anesthesia Success
Status: NOT_YET_RECRUITING
Conditions: Dental Pain and Sensation Disorder|Anesthesia, Local|Addiction, Opioid
Interventions: DRUG: articaine@ (4% 1:100000 epinephrine) dental anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Assessment of SOLO Vibrating Mesh Nebulizer for Allergen-Induced Late Asthmatic Responses
Status: UNKNOWN
Conditions: Asthma
Interventions: DEVICE: Wright jet nebulizer|DEVICE: Aerogen Solo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study To Assess The Safety And Efficacy Of The Tempsure Flexsure Applicators For Abdominal Wrinkles
Status: TERMINATED
Conditions: Wrinkle
Interventions: DEVICE: Treatment with TempSure Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT