pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Japanese Bridging Trial of Org 37462 (Study P05969)(COMPLETED)
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation
Interventions: DRUG: Ganirelix|DRUG: Ganirelix|DRUG: Ganirelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: St. John's wort|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: PROCEDURE: Positional Therapy|PROCEDURE: Intraoral Negative Pressure Therapy|PROCEDURE: Oral Appliances|PROCEDURE: Surgery|PROCEDURE: Tongue Muscle Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone (DHEA) Against Vaginal Atrophy
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Placebo|DRUG: DHEA|DRUG: DHEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Dimenhydrinate for Intraoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Dimenhydrinate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocellular Carcinoma (HCC)
Status: WITHDRAWN
Conditions: Fibrolamellar Hepatocellular Carcinoma|Hepatocellular Carcinoma (Fibrolamellar Variant)|Hepatocellular Carcinoma
Interventions: PROCEDURE: living related donor partial liver transplantation|RADIATION: Total body irradiation|PROCEDURE: Bone marrow transplant from same donor|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Filgrastim|DRUG: Tacrolimus|DRUG: mycophenolate mofetil|DRUG: Prednisone|DRUG: Antithymocyte globulin|DRUG: fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation for Consolidation After Standard Chemoradiation for Stage 3 Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: Stereotactic radiation Arm 1|RADIATION: Stereotactic radiation Arm 2|RADIATION: Stereotactic radiation Arm 3|RADIATION: Stereotactic radiation Arm 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Post-traumatic Stress Disorder|PTSD
Interventions: DRUG: Placebo|DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Study of the Intestinal Microbiota and Quality of Life in Patients Suffering From IBS Treated With Bifidice
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Probiotic Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Test of Different Kinds of Bandages on Healing of Wounds
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: 6660|DEVICE: 4314|DEVICE: 8336|DEVICE: 4840
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Anti-Diabetic Effect of Gynostemma Pentaphyllum Tea as add-on Therapy With Sulfonylureas in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: GP group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Strain Counter Strain Technique in Treatment of Lower Back Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Lower Back Myofascial Pain Syndrome
Interventions: OTHER: strain counter strain technique|OTHER: physical therapy exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [123I] AV51 and SPECT as a Marker of Beta-amyloid Protein Deposition in Subjects With Alzheimer Disease in Comparison to Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: [123I] AV-151
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Roxadustat for Reducing the Incidence of Acute Kidney Injury After Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Coronary Artery Bypass
Interventions: DRUG: Roxadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair
Status: TERMINATED
Conditions: Duration of Pain Relief
Interventions: DRUG: dexamethsone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Restricted Diet Intervention for Men on Prostate Cancer Active Surveillance
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Carbohydrate restricted diet|OTHER: Non-restricted diet|OTHER: Phone counseling with dietitian
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: danoprevir|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: placebo|DRUG: ribavirin|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Release of Epoxyeicosatrienoic Acids From Erythrocytes During the Use of Extracorporeal Procedures (Heart-lung Machine)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Valve Heart Disease
Interventions: PROCEDURE: Heart-Lung-Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Malignant Pleural Effusion
Interventions: BIOLOGICAL: tumor derived microparticles|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison and Opinion on the Safety of Teleconsultation Versus Traditional Anaesthetic Consultation in a Day Hospital
Status: COMPLETED
Conditions: Pre-anaesthetic Consultation
Interventions: OTHER: preanaesthetic classical physical consultation|OTHER: preanaesthetic teleconsultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Assess the Efficacy of Larazotide Acetate for the Treatment of Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: larazotide acetate|DRUG: placebo|DIETARY_SUPPLEMENT: 900 mg gluten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of Silicone Hydrogel Soft Contact Lenses
Status: UNKNOWN
Conditions: Myopia
Interventions: DEVICE: 41% Silicone Hydrogel Soft Contact Lenses(SHSCL)|DEVICE: ACUVUE® VITA™ (senofilcon C) Brand (Soft) Contact Lens|OTHER: Contact Lens Care Product|OTHER: Contact Lens Case
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antiplatelet Drug Resistance in Taiwanese With VASP & Platelet Mapping ™ Assay
Status: UNKNOWN
Conditions: 30 Healthy People
Interventions: DRUG: Clopidogrel and proton pump inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Open-Label, Crossover Study to Assess the Effect of Food on the Oral Bioavailability and Pharmacokinetic Profile of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Alovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Dual mTORC1/2 Inhibitor (ATG 008) or Selective Inhibitor of Nuclear Export Compound (ATG-010) in Combination With Chemotherapy in Patients With Relapsed or Metastatic Ovarian Cancer, Endometrial Cancer, and Cervical Cancer ( PORCH )
Status: UNKNOWN
Conditions: 1. Relapsed Ovarian Cancer 2. Metastatic Ovarian Cancer 3. Endometrial Cancer 4. Cervical Cancer
Interventions: DRUG: ATG-008|DRUG: ATG-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automatic Reaction to Physical Activity and Sedentary Stimuli in Aging
Status: NOT_YET_RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: Adjusted Cognitive-biased modification task|BEHAVIORAL: Cognitive-biased modification task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Neoadjuvant Chemotherapy on Cardiac Function of Perioperative Patients With Breast Cancer and New Strategies for Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Neoadjuvant Chemotherapy|Perioperative Period|Anaesthesia|Cardiac Function
Interventions: DRUG: Deoxyadrenaline|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gene Expression In Pregnancies Complicated by Preeclampsia
Status: TERMINATED
Conditions: Preeclampsia
Interventions: PROCEDURE: collection of maternal blood specimen prior to delivery|PROCEDURE: collection of placental cord blood after delivery|PROCEDURE: collection of placental tissue|PROCEDURE: collection of strip of decidua from uterine lining from cesarean section deliveries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of CBT-Based Intervention Among Patients With Liver Cancer
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety|Liver Cancer|CBT
Interventions: BEHAVIORAL: Cognitive behavioural therapy-based intervention|BEHAVIORAL: Educational group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimization of Cervical Nodal CTV for Early and Medium Stage NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: intensity-modulated radiotherapy (IMRT) with reduced-volume|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Neurobased Approach to Aphasia Therapy
Status: COMPLETED
Conditions: Aphasia, Broca|Aphasia, Wernicke|Aphasia, Fluent|Aphasia, Nonfluent|Aphasia
Interventions: BEHAVIORAL: Mobile evidence-based aphasia therapy|BEHAVIORAL: Conventional aphasia rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilostazol Verse Asprin for Vascular Dementia in Poststroke Patients With White Matter Lesions
Status: COMPLETED
Conditions: Vascular Dementia|Stroke
Interventions: DRUG: Cilostazol|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Infusions of Paclitaxel in Treating Women With Stage III or Stage IV Ovarian Cancer Refractory to Paclitaxel and Platinum
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetic Effect of AstraGin on Whey Protein Absorption and Muscle Function in Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: AstraGin (Ginseng and Astragalus Saponin Extract)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Resuscitative Thoracotomy Techniques
Status: COMPLETED
Conditions: Emergencies|Trauma|Procedural Training|Thoracotomy
Interventions: OTHER: Modified Clamshell Thoracotomy|OTHER: Left Anterolateral Thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)
Status: RECRUITING
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Sotatercept 0.3 mg/kg|DRUG: Placebo|DRUG: Sotatercept 0.3 mg/kg escalating to 0.7 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Promescent Lidocaine Spray in Men With Premature Ejaculation
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DRUG: Placebo|DRUG: Promescent Lidocaine Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Therapy and Breathing Exercise on Anxiety and Pain in Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Procedural Pain|Procedural Anxiety
Interventions: BEHAVIORAL: Music therapy|BEHAVIORAL: Breathing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Two Doses of Once Daily P2B001 in Subjects With Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),|DRUG: Placebo|DRUG: P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM
Status: COMPLETED
Conditions: Cytochrome P450 CYP2D6 Enzyme Deficiency|Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant|Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant|Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant|Cytochrome P450 CYP2C9 Enzyme Deficiency|Cytochrome P450 CYP2C19 Enzyme Deficiency|Drug Metabolism, Poor, CYP2D6-RELATED|Drug Metabolism, Poor, CYP2C19-RELATED|CYP2D6 Polymorphism
Interventions: GENETIC: Pharmacogenetic testing|OTHER: Software-based drug & gene interaction risk analysis|OTHER: MTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Insufficiency|Venous Reflux|Lower Extremity Ulcer
Interventions: DEVICE: MIST Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dalfampridine on Cognition in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: dalfampridine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Are You Looking for? Psychometric and Experimental Analyses of Reassurance Seeking in Obsessive-compulsive Disorder
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: OTHER: Cognitive-behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography Sensibilized by Oral Hydration and Hydronephrosis in Children.
Status: WITHDRAWN
Conditions: Hydronephrosis in Children
Interventions: OTHER: Ultrasonography with oral hydration|RADIATION: Scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Bafetinib as Treatment for Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL)
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: bafetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Two Copper IUDs: Mona Lisa NT Cu380 Mini and ParaGard
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Women|Female Contraception
Interventions: DRUG: Mona Lisa® NT Cu380 Mini|DRUG: ParaGard® CuT380A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Ability of Curcumin to Decrease Cytokines Involved in Mucositis in the Autologous Transplant
Status: COMPLETED
Conditions: Oral Mucositis (Ulcerative)
Interventions: DRUG: Curcumin Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thumb Hemi-Arthroplasty With Natural Kinematics; a Prospective Multicenter Study to Confirm the Safety and Efficacy of the InDx Implant
Status: NOT_YET_RECRUITING
Conditions: CMC Joint Arthritis
Interventions: DEVICE: InDx CMC Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Footwear Comfort and Performance in High School Football Players
Status: COMPLETED
Conditions: Foot|Footwear
Interventions: OTHER: Moderate Stiffness Footwear|OTHER: High Stiffness Footwear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Monitoring in Children (6 Months - 2 Years) With Electromyography and Acceleromyography
Status: RECRUITING
Conditions: Neuromuscular Blockade
Interventions: OTHER: Acceleromyography (AMG)|OTHER: Electromyography (EMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine/ Trastuzumab and Gemcitabine/ Cisplatin/ Trastuzumab in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Trastuzumab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Type 2 Diabetes Mellitus on the 2nd Day After Delivery in Women With Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes, Gestational
Interventions: PROCEDURE: Type 2 diabetes diagnosis test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria
Status: COMPLETED
Conditions: Acute Intermittent Porphyria
Interventions: GENETIC: rAAV2/5-PBGD vector dosage 1|GENETIC: rAAV2/5-PBGD vector dosage 2|GENETIC: rAAV2/5-PBGD vector dosage 3|GENETIC: rAAV2/5-PBGD vector dosage 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volumetrics and Proteomics in Shunted Normal Pressure Hydrocephalus
Status: ACTIVE_NOT_RECRUITING
Conditions: Hydrocephalus, Normal Pressure|Ventriculomegaly, Cerebral|Shunt; Complications|Hydrocephalus Acquired
Interventions: DEVICE: Initial shunt setting post-operatively of the Certas Plus shunt valve.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin for the Reduction of Opiate Use Following Pulmonary Resection (GROUP Trial)
Status: WITHDRAWN
Conditions: Thoracic|Pulmonary Disease
Interventions: DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmed/Buspirone Synergism on Shivering
Status: COMPLETED
Conditions: Hypothermia
Interventions: DRUG: dexmedetomidine|DRUG: buspirone|DRUG: Bus and Dex|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioids and Esophageal Function
Status: COMPLETED
Conditions: Pharyngeal Dysfunction|Esophageal Dysfunction
Interventions: DRUG: methylnaltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Estimate The Effects Of Food On Drug Fesoterodine Fumarate And The Pharmacokinetics Of 5-Hydroxymethyl Tolterodine (5-HMT) In Healthy Volunteers
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: fesoterodine fumarate|DRUG: fesoterodine fumarate|DRUG: fesoterodine fumarate|DRUG: fesoterodine fumarate|DRUG: fesoterodine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Therapy, Cyclophosphamide, and Cetuximab in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cetuximab|BIOLOGICAL: Pancreatic tumor vaccine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DWP708 for Treating Epidermal Growth Factor Receptor Inhibitor Related Skin Toxicities
Status: COMPLETED
Conditions: Rash Acneiform
Interventions: BIOLOGICAL: DWP708
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive Diseases
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Keratosis Palmaris et Plantaris|Psoriasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transdermal Continuous Oxygen Therapy for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Epiflo|OTHER: Moist Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability , PK/PD and Safety of Dabigatran Etexilate Oral Liquid Formulation in Children < 1 Year of Age
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: dabigatran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: APalutamiAPalutamide and stEReotactic Body Radiation Therapy for Metastatic Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Oligometastatic Hormone Sensitive Prostate Cancer
Interventions: COMBINATION_PRODUCT: SBRT on all sites of metastatic disease+Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
Status: RECRUITING
Conditions: Carcinoma|Gastrointestinal Diseases|Stomach Cancer|Gastroesophageal-junction Cancer|Digestive System Diseases|Gastric Cancer|Gastrointestinal Neoplasms
Interventions: DRUG: Anlotinib hydrochloride capsule|DRUG: Penpulimab Injection|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pegylated Interferon Alfa-2b (MK-4031) as an Adjuvant Treatment in Japanese Patients With Malignant Melanoma (MK-4031-370)
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: PegIFN alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies for Revascularization in Patients Undergoing Heart Valve Surgery With Concomitant Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease|Valvular Heart Disease
Interventions: PROCEDURE: FFR-guided surgical revascularization|PROCEDURE: Angio-guided surgical revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Rising Dose Study Investigating the Safety, Tolerability and Pharmacokinetics of Spray Dried BIBN 4096 BS After Inhalation Administration in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SD I|DRUG: SD II|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mg
Status: TERMINATED
Conditions: Hypercholesterolaemia
Interventions: BEHAVIORAL: Dietary advice|DRUG: rosuvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: India Dexamethasone and Betamethasone
Status: COMPLETED
Conditions: Preterm Birth|Antenatal Corticosteroids
Interventions: DRUG: Dexamethasone 4 mg/ml|DRUG: Betamethasone 4 mg/ml|DRUG: Celestone Soluspan 6Mg/Ml Suspension for Injection|DRUG: Dexamethasone Oral Tablet|DRUG: Betamethasone Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of Imatinib Mesylate in Patients With Idiopathic Hypereosinophilic Syndrome
Status: TERMINATED
Conditions: Hypereosinophilic Syndrome
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and "Booster" Radiation in Metastatic Adenocarcinoma of the Pancreas
Status: TERMINATED
Conditions: Adenocarcinoma of the Pancreas
Interventions: DRUG: Durvalumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Anal Carcinoma|Advanced Biliary Tract Carcinoma|Advanced Bladder Carcinoma|Advanced Breast Carcinoma|Advanced Carcinoid Tumor|Advanced Cervical Carcinoma|Advanced Colorectal Carcinoma|Advanced Gastric Carcinoma|Advanced Glioblastoma|Advanced Head and Neck Carcinoma|Advanced HER2 Positive Breast Carcinoma|Advanced Lung Carcinoma|Advanced Lung Small Cell Carcinoma|Advanced Malignant Germ Cell Tumor|Advanced Malignant Solid Neoplasm|Advanced Neuroendocrine Carcinoma|Advanced Ovarian Carcinoma|Advanced Pancreatic Carcinoma|Advanced Prostate Small Cell Neuroendocrine Carcinoma|Advanced Prostate Carcinoma|Hematopoietic and Lymphoid System Neoplasm|Multiple Myeloma|Myelodysplastic Syndrome
Interventions: PROCEDURE: Clinical Encounter|OTHER: Home Health Encounter|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Bowel Function and Quality of Life After Spinal Cord Injury
Status: RECRUITING
Conditions: Neurogenic Bowel
Interventions: DEVICE: Stimulation for blood pressure without stand|DEVICE: Stimulation for blood pressure with stand|DEVICE: Stimulation for trunk and core without stand|DEVICE: Stimulation for trunk or core with stand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease
Status: COMPLETED
Conditions: Iron Deficiency Anaemia|Iron Deficiency Anemia|Chronic Kidney Disease
Interventions: DRUG: Iron isomaltoside/ferric derisomaltose|DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose, Phase 1 Clinical Study of LCB01-0371
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LCB01-0371 800mg|DRUG: LCB01-0371 800mg BID|DRUG: LCB01-0371 1200mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yttrium Y 90 DOTA Anti-CEA Monoclonal Antibody M5A in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: high performance liquid chromatography|OTHER: pharmacological study|PROCEDURE: radionuclide imaging|PROCEDURE: single photon emission computed tomography|RADIATION: yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Study of Radiation Induced Sarcoma
Status: COMPLETED
Conditions: Radiation Induced Sarcoma
Interventions: GENETIC: tumor genetic predisposition to develop sarcoma assessment|GENETIC: tumor genetic predisposition to develop sarcoma assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy Combined With Iressa for EGFR Mutation Positive Patients With Locally Advanced Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Use of Conventional Ancillary Reaming and Single-use Ancillary Reaming Material in Total Hip Replacement
Status: COMPLETED
Conditions: Total Hip Replacement|Coxarthrosis
Interventions: DEVICE: total hip replacement with single use ancillary|DEVICE: total hip replacement with conventional ancillary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clonidine Versus Phenobarbital as Adjunctive Therapy for Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: Phenobarbital|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 0 of Neoadjuvant Lapatinib in Infiltrative Bladder Carcinoma Before Cystectomy
Status: TERMINATED
Conditions: Bladder Carcinoma|Infiltrative Bladder Carcinoma|Cystectomy
Interventions: DRUG: LAPATINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Assess the Safety and Preliminary Efficacy of PT-523 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: PT-523 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Seaweed Extract on Blood Glucose Response to Sucrose
Status: UNKNOWN
Conditions: Glucose Intolerance|Diabetes Mellitus, Type 2|Healthy Diet|Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Sucrose solution|DIETARY_SUPPLEMENT: Seaweed extract in sucrose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Neuromuscular Block Reversal With Sugammadex vs Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery
Status: COMPLETED
Conditions: Major Abdominal Surgery
Interventions: DRUG: Neostigmine|DRUG: Sugammadex|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
Status: UNKNOWN
Conditions: Dental Anxiety|Pain|Infant Behavior|Heart Rate and Rhythm Disorders
Interventions: PROCEDURE: inferior alveolar and lingual nerve block procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for HCV Genotype-6 Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa2a|DRUG: Ribavirin|DRUG: Peginterferon alfa2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CP-690,550 and Midazolam Drug-Drug Interaction Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: midazolam; CP-690,550 + midazolam|DRUG: CP-690,550 + midazolam; midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure
Status: COMPLETED
Conditions: Acute-On-Chronic Liver Failure|Cirrhosis and Chronic Liver Disease
Interventions: DIAGNOSTIC_TEST: plasma suPAR, PGE2 measurement. Other biomarkers were just recorded from clinical laboratory.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Limonene for Pulmonary Nodule Chemoprevention
Status: RECRUITING
Conditions: Pulmonary Nodules
Interventions: DRUG: Limonene capsule|DRUG: Limonene capsules(Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PVX-410 Vaccine Plus Pembrolizumab in HLA-A2+ Metastatic Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Pembrolizumab|BIOLOGICAL: PVX-410
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timely Acquirement of 12-lead ECG Using Patchy-type Wireless Device by Emergency Medical Technician in Ambulance
Status: COMPLETED
Conditions: Chest Pain|Electrocardiography
Interventions: DEVICE: patchy-type wireless ECG|DEVICE: defibrillator ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study for the "Cervical Cancer Screening and Treatment Algorithms Study Using HPV Testing in Africa"
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Infection
Interventions: DIAGNOSTIC_TEST: HPV DNA Test|DIAGNOSTIC_TEST: VIA triage test|PROCEDURE: Treatment by ablative treatment|PROCEDURE: Colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: The Influence of Prepartum Perineal Training With the Epi-No Device on Pelvic Floor Function.
Status: COMPLETED
Conditions: Dyspareunia|Urinary Incontinence|Perineal Tear|Perineal Injury|Episiotomy Wound|Episiotomy; Complications
Interventions: DEVICE: Epino
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acceptance of Different Thickeners in Dysphagia
Status: COMPLETED
Conditions: Dysphagia|Dysphagia, Oropharyngeal
Interventions: DIETARY_SUPPLEMENT: Modified starch without flavoring|DIETARY_SUPPLEMENT: Mofidied starch with Bi1 aromas|DIETARY_SUPPLEMENT: Xanthan gum without flavoring|DIETARY_SUPPLEMENT: Xanthan gum with Bi1 aromas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Meningococcal Group ACYW135 Conjugate Vaccine in 2-month to 55 Years Old Population.
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal Group ACYW135 Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Incretin-based Drugs and Acute Pancreatitis
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DPP-4 inhibitors|DRUG: GLP-1 analogs|DRUG: Insulins|DRUG: Biguanides|DRUG: Sulfonylureas|DRUG: Thiazolidinediones|DRUG: Alpha-glucosidase inhibitors|DRUG: Meglitinides
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Making Health Care Safer for Older Adults Receiving Skilled Home Health Care Services After Hospital Discharge
Status: COMPLETED
Conditions: Transitional Care|Frail Elderly|Home Health Care
Interventions: BEHAVIORAL: Transition Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Electrophysiological Effects of Irbesartan in Patients With Paroxysmal Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Irbesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Test Validity of Structural Vertebral Endplate Defects
Status: UNKNOWN
Conditions: Defect of Vertebral Endplate (Disorder)
Interventions: DIAGNOSTIC_TEST: clinical Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Buccal Fat Pad and Platelet Rich Fibrin After Ultrasonic Hydrodynamic Maxillary Sinus Membrane Elevation
Status: UNKNOWN
Conditions: Maxillary Sinus
Interventions: OTHER: ultrasonic hydrodynamic maxillary sinus lift buccal pad fat|OTHER: ultrasonic hydrodynamic maxillary sinus lift platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study on Metabolic Parameters of Sertindole in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Sertindole|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pixantrone in CD20+ Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Aggressive Non-Hodgkin Lymphoma
Interventions: DRUG: Pixantrone|OTHER: Ifosfamide|OTHER: Etoposide|OTHER: Rituximab|PROCEDURE: Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DOORS: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Change From Dipeptidyl Peptidase-4 Inhibitor (DPP4i) Treatment to Oral Semaglutide in Italy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurofibromatosis Type 1 Tumor Early Detection Study
Status: RECRUITING
Conditions: Neurofibromatosis Type 1|Neurofibromatosis 1|Plexiform Neurofibroma|Plexiform Neurofibromas|Malignant Peripheral Nerve Sheath Tumor|Malignant Peripheral Nerve Sheath Tumors|Atypical Neurofibroma
Interventions: DIAGNOSTIC_TEST: Liquid biopsy for MPNST development
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
Status: WITHDRAWN
Conditions: Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder|Agoraphobia
Interventions: DRUG: 50:2 mg(CBD:THC)/ml - Cannabinoid Oil Oral Preparation- titrated as tolerated up to a maximum 8mls twice daily (200 mg- 800 mg total dose)|DRUG: Placebo Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Two Daily Disposable Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Delefilcon A contact lenses|DEVICE: Narafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases
Interventions: DRUG: Olmesartan medoxomil|DRUG: Calcium channel blockers (amlodipine, azelnidipine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Everolimus Beyond Progress for Patients Who Had Progress Under Everolimus and Exemestane
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Everolimus-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Petersen's Hernia After Laparoscopic Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Petersen's Hernia
Interventions: PROCEDURE: Closure method of Petersen's space|PROCEDURE: Mesentery fixation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Seasonale for Treatment of Low Bone Mineral Density
Status: WITHDRAWN
Conditions: Osteopenia
Interventions: DRUG: Seasonale (levonorgestrel and ethinyl estradiol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD)
Status: TERMINATED
Conditions: Familial Partial Lipodystrophy|Metabolic Abnormalities
Interventions: DRUG: REGN4461|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Gabapentin in Management of Chronic Pelvic Pain in Females: A Randomised Placebo-controlled Study.
Status: UNKNOWN
Conditions: Pelvic Pain
Interventions: DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Migraine Management Mobile App Combined With Electrophysiological Measurements for Identification of Migraine Attack Risk and Beneficial Preventive Actions.
Status: UNKNOWN
Conditions: Migraine
Interventions: DEVICE: BEI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY