pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Continuous Positive Airway Pressure and Valsartan Treatments on Arterial Blood Pressure in OSAS Patients
Status: COMPLETED
Conditions: Hypertension,|Obstructive Sleep Apnea
Interventions: DEVICE: Continuous positive airway pressure (CPAP)|DRUG: Valsartant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Vitamin D Supplementation on Pain in Women With Primary Dysmenorrhea and Hypovitaminosis D
Status: UNKNOWN
Conditions: Hypovitaminosis D
Interventions: DRUG: Ergocalciferol Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of NN1250 Versus Insulin Detemir, Both Combined With Insulin Aspart in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin detemir|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potency pReservation In Prostate cAncer Patients Treated With UltraSound-guided Low-dose Rate Brachytherapy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Low dose rate (LDR) brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LMP1- and LMP2-Specific CTLs to Patients With EBV-Positive NPC (NATELLA)
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: Genetically modified CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology Enhanced Behavioral Activation Treatment for Substance Use
Status: COMPLETED
Conditions: Substance-Related Disorders|Depressive Disorder|Behavioral Symptoms|Risk-Taking|Sexual Behavior
Interventions: BEHAVIORAL: LETS ACT|BEHAVIORAL: LETS ACT-SE|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Metaglidasen in Type 2 Diabetes in Patients Suboptimally Controlled on Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: MBX-102|DRUG: MBX-102|DRUG: MBX-102|DRUG: Placebo|DRUG: Actos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Supervised Training Program on Functional Capacity in Patients With HFpEF and Chronotropic Incompetence
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Chronotropic Incompetence
Interventions: BEHAVIORAL: Supervised aerobic training|BEHAVIORAL: Supervised aerobic plus low to moderate-intensity strength training|BEHAVIORAL: Supervised aerobic plus moderate to high-intensity strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Alone Versus Sorafenib Combined With HAIC for Advanced HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Folfox Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Treatment Adherence in Pediatric Asthma With a Problem Solving Intervention
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Tailored Problem Solving Intervention|BEHAVIORAL: Family Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Investigation of Non-CE Marked Intermittent Catheters for Females
Status: COMPLETED
Conditions: Retention, Urinary
Interventions: DEVICE: SpeediCath® Standard female|DEVICE: New intermittent Variant 1 catheter for females|DEVICE: New intermittent Variant 2 catheter for females
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testosterone Replacement in Postmenopausal Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: Testosterone patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo
Status: UNKNOWN
Conditions: Retinal Artery Occlusion
Interventions: BIOLOGICAL: Hypoxia|DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Treatment Efficacy With High and Medium Dose of Fluticasone in Combination With Salmeterol in COPD Patients
Status: UNKNOWN
Conditions: Percentage of Annual Acute Exacerbation|Quality of Life
Interventions: DRUG: Fluticasone/Salmeterol high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Pharmacokinetics and Safety of Long-acting Injectable Risperidone When Administered to Gluteal or Deltoid Intramuscular Injection Sites in Stable Schizophrenia Patients.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone long-acting injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of tDCS Combined With Balance Training on Lower Limbs Spasticity in Chronic Stroke Patients
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Chidamide Plus Endocrine in Maintenance Treatment of HR+/HER2- Breast Cancer After First-line Chemotherapy
Status: RECRUITING
Conditions: HR Positive HER2 Negative Advanced Breast Cancer
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Carilizumab and Apatinib for Recurrent High-Grade Glioma
Status: UNKNOWN
Conditions: Neoadjuvant Therapy|Carilizumab|Apatinib|Recurrent High-Grade Glioma
Interventions: BIOLOGICAL: PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy as a Drug Delivery System
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Cardinal Pro +Simultaneous Irrigation (NPWTi)|DEVICE: Cardinal Pro (NPWT) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Postoperative Radiotherapy With Kidney Sparing Surgery for Locally Advanced High-risk Ureteral Cancer
Status: RECRUITING
Conditions: Locally Advanced|Urothelial Carcinoma Ureter
Interventions: PROCEDURE: Radical surgery|RADIATION: Kidney sparing surgery+Postoperative radiotheray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erythropoietin for Anemia Due to Zidovudine in Human Immunodeficiency Virus Infection
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|Anemia|Hematologic Diseases|HIV Infections|Blood Disease
Interventions: PROCEDURE: erythropoietin, recombinant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Popliteal Plexus Block for Total Knee Arthroplasty
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine-EPINEPHrine 0.5%-1:200,000 Injectable Solution|OTHER: Sodium Chloride 0.9 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurodegenerative Diseases|Neurocognitive Disorders|Mental Disorders
Interventions: DRUG: XPro1595
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Anticonvulsant Efficacy of Passiflora Incarnata Extract in Patients With Partial Epilepsy
Status: WITHDRAWN
Conditions: Partial Epilepsy
Interventions: DRUG: Botanical extract from Passiflora incarnata
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
Status: COMPLETED
Conditions: Antiphospholipid Antibody Syndrome|End Stage Renal Disease
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Trans-anal total mesorectal excision(TaTME)|PROCEDURE: Lap. TME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Intervention on Anxiety, Fear, and Pain in Pediatric Patients Receiving Intrathecal Chemotherapy
Status: COMPLETED
Conditions: Nurse's Role
Interventions: BEHAVIORAL: Music intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AAV1-CMV-Serca2a GENe Therapy Trial in Heart Failure
Status: TERMINATED
Conditions: Heart Failure Congestive|Ischemic Cardiomyopathy|Non-ischemic Cardiomyopathy
Interventions: GENETIC: MYDICAR-single intracoronary infusion|GENETIC: Placebo; single intracoronary infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effectiveness Between Existing Treatment and New Treatment
Status: TERMINATED
Conditions: P. Falciparum Malaria
Interventions: DRUG: Mefloquine+Artesunate|DRUG: Dihydroartemisinin-Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Frequency of Occurrence and Defining the Most Appropriate Screening Test for Anal Intraepithelial Neoplasia (AIN) in Patients With Human Papillomavirus (HPV) Related Gynecological Diseases.
Status: RECRUITING
Conditions: HPV-Related Carcinoma|HPV Infection
Interventions: DIAGNOSTIC_TEST: hrHPV test and cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Absolute Bioavailability, Safety, and Tolerability of Subcutaneous GS-5745 in Healthy Adults
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: GS-5745 SC|DRUG: GS-5745 IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Importance of Integrated Pulmonary Index in Pediatric Bronchoscopy
Status: COMPLETED
Conditions: Monitored Anesthesia Care|Respiratory Monitoring
Interventions: DEVICE: Integrated Pulmonary Index (IPI) monitoring|DRUG: propofol|DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Delivery of "Doing What Matters in Times of Stress: An Illustrated Guide"
Status: COMPLETED
Conditions: Stress|Quality of Life|Depressive Symptoms
Interventions: BEHAVIORAL: Doing What Matters in Times of Stress: An Illustrated Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms?
Status: WITHDRAWN
Conditions: Laryngomalacia|Acid Reflux|Stridor
Interventions: DRUG: ranitidine or famotidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nanotechnology for Detection of Multiple Sclerosis Compared to Autoimmune and Neurological Diseases by Exhaled Samples
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: NA-NOSE artificial olfactory system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Induction to Buprenorphine/Naloxone
Status: TERMINATED
Conditions: Opioid Use Disorder|Opioid Use|Opioid Abuse|Opioid Misuse|Opioid Dependence
Interventions: DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-range Finding Efficacy and Safety Study for QBW251 in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: QBW251|DRUG: Placebo|DRUG: COPD maintenance background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Testosterone Nasal Gel for Treating Hypogonadism in Men.
Status: UNKNOWN
Conditions: Hypogonadism
Interventions: DRUG: Nasotestt 5 mg|DRUG: Androgel 50 mg|OTHER: Nasotestt Placebo|OTHER: Androgel Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cytisinicline for Vaping Cessation in Adult Smokers
Status: COMPLETED
Conditions: Vaping|E-Cig Use
Interventions: DRUG: cytisinicline|DRUG: Placebo|BEHAVIORAL: Behavioral support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orange Juice, Hesperidin and Their Role in Vascular Health Benefit
Status: COMPLETED
Conditions: Metabolic Syndrome|Vascular Compliance|Predisposition to Cardiovascular Disease
Interventions: BEHAVIORAL: Beverage consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Duloxetine in Adolescents With Juvenile Primary Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Randomized, Placebo-Controlled Safety and Tolerability Study Of Intravenous SBS-1000 in Healthy Adults
Status: RECRUITING
Conditions: Pain|Acute Pain
Interventions: DRUG: SBS-1000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HDR vs LDR Brachytherapy as Monotherapy in the Treatment of Localized Prostate Cancer.
Status: UNKNOWN
Conditions: Adenocarcinoma of Prostate
Interventions: RADIATION: LDR Brachytherapy|RADIATION: HDR Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study of the Aqueous Humor Dynamics of AR-13324 Ophthalmic Solution in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Netarsudil (AR-13324) Ophthalmic Solution|DRUG: Netarsudil (AR-13324) Ophthalmic Solution Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Task Training on Upper Extremity Functions in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: STROKE REHABİLİTATİON
Interventions: OTHER: Control Group|OTHER: Study Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Thrombectomy of Acute Ischemic Stroke Anterior Circulation Distal Vessel Occlusion
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: an array of devices are used in thrombectomy. These include guide catheters, stent-retrievers, microcatheters, aspiration catheters, and aspiration pump systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Self Directed Learning and Small Group Teaching Methods on Pressure Injury Assessment
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: OTHER: Small-group Teaching|OTHER: Self-directed Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Initiation of Extracorporeal Life Support in Refractory OHCA
Status: COMPLETED
Conditions: Cardiac Arrest|Out-Of-Hospital Cardiac Arrest|Sudden Cardiac Death
Interventions: PROCEDURE: Extracorporeal cardiopulmonary resuscitation (ECPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cervical Taping on Neck Pain and Kinematics in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Cervical Pain|Chronic Pain
Interventions: OTHER: Cervical Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Blended Lifestyle Intervention to Promote Physical Activity, Diet, and Health in Hong Kong Older Adults
Status: COMPLETED
Conditions: Health Behavior|Physical Activity|Healthy Diet
Interventions: BEHAVIORAL: Blended intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: afatinib|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne|Muscular Dystrophies|Muscular Disorders, Atrophic|Muscular Diseases|Musculoskeletal Diseases|Neuromuscular Diseases|Nervous System Diseases|Genetic Diseases, X-Linked|Genetic Diseases, Inborn
Interventions: DRUG: Ataluren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation
Status: COMPLETED
Conditions: Left Ventricular Diastolic Dysfunction|Weaning Failure|Mechanical Ventilation Complication|Diaphragmatic Disorder
Interventions: DIAGNOSTIC_TEST: transthoracic echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome)
Status: RECRUITING
Conditions: Chinese Medicine|Stable Coronary Heart Disease|Chronic Insomnia|Headache|Endometriosis
Interventions: DRUG: Xuefu-Zhuyu Capsule|DRUG: placebo|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Bio-C/T Followed by Concurrent Bio-R/T in High-risk Locally Advanced Oral Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Oral Cancer
Interventions: DRUG: Cetuximab,Paclitaxel,Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, Clinical Phase II Study
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: PROCEDURE: Anesthesia before transurethral resection of the bladder tumor|DRUG: Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of BIBF1120 (Nintedanib) in Patients With Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck
Status: UNKNOWN
Conditions: Recurrent or Metastatic Salivary Gland Cancer of the Head and Neck
Interventions: DRUG: BIBF1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Adjuvant Chemotherapy With GS in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Gemcitabine, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Optimization Pilot to Optimize An Early Palliative Care Intervention for Advanced Heart Failure
Status: RECRUITING
Conditions: Heart Failure NYHA Class III|Heart Failure NYHA Class IV|Chronic Illness
Interventions: BEHAVIORAL: UPHOLDS (Utilizing Palliative Care for Heart Failure Optimized using Lay Navigators to Decrease Suffering)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation
Status: NOT_YET_RECRUITING
Conditions: Myeloproliferative Neoplasms
Interventions: DRUG: Ivosidenib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Versus Phenytoin in Management of Pediatric Status Epilepticus
Status: UNKNOWN
Conditions: Comparison|the Efficacy of Levetireacetam|Phenytoin|Management of Pediatric Status Epilepticus
Interventions: DRUG: Levetiracetam Injection|DRUG: Phenytoin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab for Prevention of Chronic GVHD
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Rituximab|DRUG: 375 mg/m2 RRituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Granulocyte Colony-stimulating Factor (G-CSF) Plus or Minus AMD3100 for Engraftment Post Allogeneic Transplant
Status: COMPLETED
Conditions: Stem Cell Transplant Patients
Interventions: DRUG: G-CSF|DRUG: AMD3100|PROCEDURE: Leukapheresis|PROCEDURE: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restrictive- vs Individualized Goal Directed Fluid Therapy in Liver Surgery
Status: COMPLETED
Conditions: Surgery-Complications
Interventions: PROCEDURE: individualized GDFT|PROCEDURE: Restrictive fluid therapy strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Use in Non-RSV Bronchiolitis
Status: TERMINATED
Conditions: Bronchiolitis, Viral
Interventions: DRUG: Placebos|DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Tablet Forms of MK0974 (0974-045)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK0974 Ethanolate formulation|DRUG: Comparator: MK0974 Hydrate formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Comfort: A Trial on the Incrediwear Back Brace in Patients With Chronic Lower Back Pain
Status: RECRUITING
Conditions: Low Back Pain|Back Pain
Interventions: DEVICE: Incrediwear Daytime Back Brace|DEVICE: Incrediwear Sham Daytime Back Brace|DEVICE: Control Daytime Back Brace|DEVICE: Incrediwear 24 Hour Back Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Efficacy and Safety of Crisaborole in Adults With Stasis Dermatitis
Status: COMPLETED
Conditions: Stasis Dermatitis
Interventions: DRUG: crisaborole ointment|OTHER: vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hearing Aid Noise Reduction in Pediatric Users (Oticon Study)
Status: COMPLETED
Conditions: Hearing Impairment|Hearing Loss, Sensorineural
Interventions: DEVICE: Oticon OpenSound Navigator speech enhancement algorithm|DEVICE: Oticon omni-directional microphone algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ethanol-lock Therapy for the Prevention of Non-tunneled Catheter-related Infection in Pediatric Patients
Status: COMPLETED
Conditions: Infection, Catheter-Related|Central Line-associated Bloodstream Infection (CLABSI)|Pediatric
Interventions: DRUG: Ethanol-lock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Operative Versus Non Operative Treatment of Proximal Humerus (Shoulder Joint) Fractures
Status: UNKNOWN
Conditions: 3 and 4 Part Proximal Humerus Fractures
Interventions: OTHER: Open reduction internal fixation; reduction and immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Exercise in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis|Raynaud's Phenomenon|Quality of Life
Interventions: OTHER: Exercise intervention - Cycling|OTHER: Exercise intervention - arm cranking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acellular Dermal Matrix Versus Tenting Technique in Peri-implant Soft Tissue Augmentation and Crestal Bone Stability
Status: COMPLETED
Conditions: Soft Tissue Augmentation
Interventions: PROCEDURE: Acellular Dermal Matrix|PROCEDURE: Soft Tissue Expansion using Tenting Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Carcinoma in the Liver|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DEVICE: Y-90 SIR-Spheres|PROCEDURE: Yttrium-90 Microsphere Radioembolization|OTHER: Systemic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy in Patients With Relapsing-Remitting Multiple Sclerosis (MS)CombiRx
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta 1-a|DRUG: glatiramer acetate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance, and Pharmacokinetics of Single Rising Oral Doses of BILB 1941 ZW Solution in Healthy Male Subjects, Followed With Bioavailability Comparison of BILB 1941 ZW Tablet and Solution Formulation Administered With or Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILB 1941 ZW - single rising dose part|DRUG: Placebo|DRUG: BILB 1941 ZW - solution|DRUG: BILB 1941 ZW - tablet|OTHER: standardized breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of Macrophage Activation in Lung Injury Following Ozone Exposure
Status: RECRUITING
Conditions: Air Pollution
Interventions: OTHER: Clean Air|OTHER: Ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Performance of Molecular Breast Imaging (MBI) to Magnetic Resonance Imaging (MRI) of the Breast in Identifying and Excluding Breast Carcinoma in Women at High Risk for Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tc99m sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study to Determine the Safety of the Combination of Ontak in Combination With CHOP in Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: Ontak|DRUG: CHOP (cyclophosphamide (C), adriamycin (H), vincristine (O), and prednisone (P)) chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous FL058 Administered in Healthy Subjects(SAD/MAD)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FL058|DRUG: Placebo|DRUG: FL058|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VSN16R for the Treatment of Spasticity in Multiple Sclerosis
Status: COMPLETED
Conditions: Spasticity in People With Multiple Sclerosis
Interventions: DRUG: VSN16R|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of MPC-4326 for Treatment of Patients With HIV-1 Infection.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: bevirimat dimeglumine|DRUG: bevirimat dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tc99m Sestamibi Molecular Breast Imaging
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Molecular Breast Imaging (MBI)|DRUG: Tc99m sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Decision Impact Trial of the ExoDx Prostate (IntelliScore)
Status: UNKNOWN
Conditions: Cancer of the Prostate
Interventions: DIAGNOSTIC_TEST: ExoDx Prostate (IntelliScore)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Acupuncture in the Modulation of Peripheral Oxidative Stress Insomnia
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: OTHER: Electroacupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin for the Treatment of Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Intranasal Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the GlucoMe APP in Patients With Uncontrolled Diabetes Treated With MDI
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1 or 2
Interventions: DEVICE: GlucoMe App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers
Status: UNKNOWN
Conditions: Bioequivalence|Asthma
Interventions: DRUG: Test|DRUG: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer
Status: COMPLETED
Conditions: Newly Diagnosed Oligometastatic Prostate Cancer
Interventions: PROCEDURE: radical prostatectomy|RADIATION: stereotactic body radiotherapy|DRUG: Leuprolide|DRUG: apalutamide|DRUG: abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Atrial Fibrillation
Interventions: DRUG: Metoprolol|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab Plus Gemcitabine in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma-HN17-11
Status: COMPLETED
Conditions: Recurrent or Metastatic Nasopharyngeal Carcinom
Interventions: DRUG: Gemcitabine+ nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Immune Response Following Zoster Vaccination to Subjects With Rheumatoid Arthritis Receiving Tofacitinib or Placebo With Background Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tofacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study of VELCADE Alone and VELCADE Plus Irinotecan in Patients With Relapsed or Refractory Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: VELCADE TM (bortezomib) for Injection, or PS-341
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: CTP-692|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Iliac Arterio-venous Fistula for Treatment of Neurally Mediated Syncope Study
Status: UNKNOWN
Conditions: Neurally Mediated Syncope
Interventions: DEVICE: ROX COUPLER|PROCEDURE: Right heart catheterisation and routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine D-amino Acid Oxidase Brain Enzyme Occupancy of TAK-831 After Single-dose Oral Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TAK-831|DRUG: [18F]PGM299
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Mindfulness-Based Cognitive Therapy Program Applied to Nursing Students
Status: COMPLETED
Conditions: Mindfulness|Depression, Anxiety|Stress|Nursing Students
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Interventional Study to Evaluate the Effect of Ivabradine on Exercise Capacity in Heart Transplant Recipients
Status: WITHDRAWN
Conditions: Heart Transplantation, Elevated Resting Heart Rate
Interventions: DRUG: Ivabradine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cusatuzumab|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: BCX9930 monotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease (MRFIT)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: antihypertensive agents|BEHAVIORAL: smoking cessation|BEHAVIORAL: diet, fat-restricted|DRUG: diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Add-on Video-based Training on Mental Status Examination Skills
Status: COMPLETED
Conditions: Medical Education
Interventions: OTHER: Video-based self-regulated training on the mental status exam|OTHER: E-course with written material on the mental status exam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Bifurcation Lesion
Interventions: OTHER: Hybrid DEB approach with drug-eluting balloon|OTHER: Two-stent strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neuropeptide Y and Sympathovagal Balance
Status: COMPLETED
Conditions: Physical Activity|Sympathetic Nervous System|Secretion; Catecholamine
Interventions: DRUG: Saxagliptin 5mg|DRUG: Placebo oral capsule|OTHER: ergometric test in healthy volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing FEES to VFSS in Diagnosing Laryngeal Penetration and Aspiration in Infants in the NICU
Status: COMPLETED
Conditions: Deglutition Disorders
Interventions: OTHER: VFSS|OTHER: FEES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Lisdexamfetamine Sulfate to Treat Cognitive Dysfunction in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: lisdexamfetamine sulfate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Isolation Methods in Pediatric Patients
Status: WITHDRAWN
Conditions: Dental Plaque|Calculus, Dental|Aerosol Disease
Interventions: DEVICE: The saliva ejector|DEVICE: The high-volume evacuator|DEVICE: The DryShield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Anodal and Cathodal tDCS Combined With Conventional Physical Therapy in Patients With Acute Stroke
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate Viral Shedding in Healthy Children Vaccinated With Vaccine Virus Liquid (CAIV-T)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CAIV-T, Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: TC or BEP in Treating Patients With Malignant Ovarian Germ Cell Tumors
Status: RECRUITING
Conditions: Ovarian Germ Cell Cancer|Ovarian Neoplasms|Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bleomycin|DRUG: Etoposide|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis
Status: COMPLETED
Conditions: MPN (Myeloproliferative Neoplasms)
Interventions: DRUG: Itacitinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Status: RECRUITING
Conditions: Stage I Breast Cancer
Interventions: OTHER: Radiation and Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane)|DRUG: Endocrine Therapy (Tamoxifen, Anastrozol, Letrozole, Exemestane)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of a VR Exposure-based Eye Contact Training‬ to Reduce Fear of Public Speaking
Status: COMPLETED
Conditions: Fear of Public Speaking (Subclinical)
Interventions: OTHER: Exposure-based eye contact training in Virtual Reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study of GPA33-specific PET/CT for the Diagnosis of Colorectal Cancer
Status: RECRUITING
Conditions: Positron-Emission Tomography|Colorectal Neoplasms
Interventions: RADIATION: [68Ga]Ga-NOTA-WWH347 or [18F]F-H3RESCA-WWH347
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
Status: TERMINATED
Conditions: Ileus|Gastro-Intestinal Disorder
Interventions: DRUG: LB1148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorpheniramine Maleate Nasal Spray for Chronic Rhinitis
Status: WITHDRAWN
Conditions: Allergic Rhinitis|Nasal Congestion
Interventions: DRUG: CPM|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Treatment Effects on Individuals With Chronic Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow|Lateral Epicondylitis|Tendinopathy
Interventions: OTHER: Radial Extracorporeal Shock Wave Therapy|OTHER: Deep Friction Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT