pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pomegranate Extract Supplementation in Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Standard pomegranate extract formulation|DIETARY_SUPPLEMENT: Pomegranate extract formulation-1|DIETARY_SUPPLEMENT: Pomegranate extract formulation-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Ventilation vs Face Mask
Status: UNKNOWN
Conditions: Nasotracheal Intubation
Interventions: PROCEDURE: face mask ventilation crossover nasal ventilation|PROCEDURE: nasal ventilation crossover face mask ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liver Transplantation for Hepatocellular Carcinoma Arising in Non-cirrhotic Liver: a Propensity Score-matched Retrospective Cohort Study of Two National Databases
Status: COMPLETED
Conditions: Hepatocellular Carcinoma, Non-cirrhotic Liver
Interventions: OTHER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Toripalimab as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Advanced Cancer
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function
Status: TERMINATED
Conditions: Pain|Terminal Illness|Renal Impairment
Interventions: DRUG: Oxycodone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Simulation in Chronic Migraine
Status: UNKNOWN
Conditions: Migraine Disorders
Interventions: DEVICE: TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Prevalence of Extended-Spectrum Betalactamase Producing Enterobacteriaceae Among ICU Staff
Status: UNKNOWN
Conditions: Antibiotic Resistance|Extended-spectrum Betalactamase|Enterobacteriaceae|Escherichia Coli
Interventions: OTHER: ESBL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metacognitive Therapy for Patients With Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Metacognitive Therapy|BEHAVIORAL: Exposure and Response Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of Urinary Gluten Immunogenic Peptides in Monitoring the Adherence to Gluten-free Diet.
Status: COMPLETED
Conditions: Celiac Disease
Interventions: BEHAVIORAL: Gluten (behaviour)|BEHAVIORAL: Placebo (behaviour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Efficacy, and Tolerability Study of ASP3291 in Patients With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: ASP3291|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dexanabinol in Combination With Chemotherapy in Patients With Advanced Tumours
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Pancreatic Cancer
Interventions: DRUG: Dexanabinol|DRUG: Sorafenib|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Pegcetacoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm.
Status: TERMINATED
Conditions: Kidney Stone|Expulsive Medical Therapy
Interventions: DRUG: Silodosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults
Status: COMPLETED
Conditions: Substance-Related Disorders
Interventions: DRUG: RDC-0313 + Buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab in Participants With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriasis, Arthritic
Interventions: DRUG: Ixekizumab|DRUG: Placebo|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
Status: COMPLETED
Conditions: Metallosis|Pain|Total Hip Replacement|Total Knee Replacement
Interventions: BEHAVIORAL: Questionnaires|BEHAVIORAL: Interviews|OTHER: Blood draw|RADIATION: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Prospect of Using Serum Taurine Level as a Potential Biomarker for Early Detection of Colorectal Carcinoma and Its Correlation With Other Prognostic Markers
Status: COMPLETED
Conditions: Taurine in Cancer Colon
Interventions: DIAGNOSTIC_TEST: Taurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Foot Orthotics in Veterans With Chronic Lower Back Pain
Status: TERMINATED
Conditions: Back Pain Lower Back Chronic
Interventions: DEVICE: Custom Foot Orthotic|DEVICE: Sham Orthotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension
Status: COMPLETED
Conditions: Post-spinal Anesthesia Hypotension
Interventions: DIAGNOSTIC_TEST: Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block
Status: TERMINATED
Conditions: Fracture of Foot
Interventions: DRUG: Bupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation After Kidney Transplant
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type I
Interventions: DRUG: Low Molecular Weight Sulfated Dextran|DRUG: Heparin|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus|DRUG: Tacrolimus|DRUG: Cyclosporine|DRUG: Daclizumab|DRUG: Basiliximab|BIOLOGICAL: Allogeneic Pancreatic Islet Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Abortion in the Second Trimester
Status: COMPLETED
Conditions: Abortion, Second Trimester
Interventions: DRUG: hyoscine N-butyl bromide under the generic name of buscopan ampoule produced by Sanofi company|DRUG: misoprostol under the generic name of misotac tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medico-economic Impacts of NeLLY Service for Not on Dialysis Severe Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease stage4|Kidney Diseases
Interventions: DEVICE: NeLLY service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Allogenic CD19-targeting CAR-γδT Cell Therapy in r/r NHL
Status: RECRUITING
Conditions: Non Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Allogenic CD19-CAR-γδT cell|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Treatment for Knee Osteoarthritis With Sensitive Acupoints and Tender Points
Status: COMPLETED
Conditions: Acupuncture|Knee Osteoarthritis|Sensitive Acupoints|Tender Points
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Comprehensive Augmented and Virtual Reality in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Augmented reality and virtual reality rehabilitation|BEHAVIORAL: Conventional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of ION904 in Participants With Uncontrolled Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: ION904|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Smoking and Gingival Crevicular Fluid Markers on Coronally Advanced Flap Outcomes
Status: COMPLETED
Conditions: Gingival Recession|Smoking
Interventions: PROCEDURE: Coronally Advanced Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Protocol for CLL With Fludarabine and Cyclophosphamide With Rituximab (FCR) Plus Lenalidomide
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Fludarabine, Cyclophosphamide, Rituximab, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHangeovers of Norepinephrine in Intensive Care
Status: UNKNOWN
Conditions: Shock|Intensive Care
Interventions: PROCEDURE: changeover|DEVICE: use of automatic infusion pump|BEHAVIORAL: datas collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia of Adult Patients Undergoing Ovarian Cancer Surgery
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: PROCEDURE: erector spinae block|PROCEDURE: transversus abdominis block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Fruit and Vegetable Intake Promotion. "The UVa Community Eats Healthy" Study Protocol (University of Valladolid)
Status: COMPLETED
Conditions: Fruit and Vegetable Consumption
Interventions: BEHAVIORAL: Increase of fruit and vegetable consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fractionated Dosing Study: Study to Evaluate Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies
Status: COMPLETED
Conditions: Non-Myeloid Malignancies|Anemia|Cancer
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-inferiority Study Comparing Two Heparin Sodium Preparations in Hip Fracture Surgery
Status: TERMINATED
Conditions: Hip Fracture Surgery
Interventions: BIOLOGICAL: Heparin Sodium - Eurofarma|BIOLOGICAL: Heparin Sodium - APP Pharmaceuticals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Three Kinds of Postoperative Analgesia After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain|Complications
Interventions: PROCEDURE: Local analgesic|PROCEDURE: Nerve Block|PROCEDURE: Intravenous analgesic|DRUG: ropivacaine|DRUG: ropivacaine|DRUG: opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Cancer|Pancreatic Cancer|Pancreas Cancer|Pancreatic Adenocarcinoma Resectable|Pancreatic Ductal Adenocarcinoma|Pancreatic Metastasis
Interventions: DRUG: Ascorbic Acid|DRUG: Paclitaxel protein-bound|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis
Status: COMPLETED
Conditions: Acidosis, Renal Tubular|Nephrolithiasis|Vacuolar Proton-Translocating ATPases
Interventions: DRUG: Furosemide-Fludrocortisone-Test (test for urinary acidification)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy
Status: UNKNOWN
Conditions: Atrial Fibrillation Ablation
Interventions: PROCEDURE: PVI using an open irrigated tip catheter|PROCEDURE: PVI using a closed irrigated tip catheter|PROCEDURE: PVI using a cryoballoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Sitagliptin on Cardiovascular Exercise Performance in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Disease
Interventions: DRUG: Sitagliptin|DRUG: Glimepiride|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency|Growth Hormone Disorder
Interventions: DRUG: somapacitan|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Renal Impairment on the Blood Levels of Daclatasvir (DCV), Asunaprevir (ASV) and BMS-791325 After Multiple Doses of a Fixed Dose Combination Tablet
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: DCV 3DAA FDC|DRUG: BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas
Status: COMPLETED
Conditions: Soft Tissue Sarcoma|Bone Sarcoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness And Safety Study Of PD 0299685 For The Treatment Of Symptoms Associated With Interstitial Cystitis
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome
Interventions: DRUG: PD 0299685 at 15mg BID|DRUG: PD 0299685 at 30mg BID|DRUG: placebo for PD 0299685
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: JTT-130|DRUG: JTT-130 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Topical 10% Metronidazole Ointment for the Treatment of Active Perianal Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: 10% Metronidazole Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Preload Responsiveness in ARDS Patients During Prone Position
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Septic Shock|Hemodynamic Instability
Interventions: OTHER: Tidal volume challenge|OTHER: End-expiratory occlusion test|OTHER: Trendelenburg maneuver
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Umeclidinium Bromide in Combination With Fluticasone Furoate in COPD Subjects With an Asthmatic Component
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF|DRUG: UMEC|DRUG: VI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of New Treatment for Excessive Alcohol Users by Electric Stimulation of Nerves Around Ear
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Drug Relief V(version) 2.0 Auricular Percutaneous Electrical Neural Field Stimulation (PENFS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Treatment of Patients With Immune Thrombocytopenic Purpura
Status: TERMINATED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Dexamethasone USP Micronized|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single-Dose Gabapentin in Subjects With Transient Insomnia Induced by a Sleep Phase Advance
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UNITY 1: A Study of an Investigational Treatment Regimen of Daclatasvir (DCV) + Asunaprevir (ASV) + BMS-791325 in a Fixed Dose Combination (the DCV 3DAA (Direct Acting Antiviral) Regimen) for 12 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Genotype 1 Infection in Non-cirrhotic Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: DCV/ASV/BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures
Status: TERMINATED
Conditions: Refractory Partial Onset Seizures
Interventions: DRUG: Rufinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer Stage IV
Interventions: DRUG: Abemaciclib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Changes in Diabetes in Adults and Children Using Multispectral Optoacoustic Tomography.
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 1|Macroangiopathy
Interventions: DEVICE: Multispectral optoacoustic tomography|DIAGNOSTIC_TEST: Ankle Brachial Index|DIAGNOSTIC_TEST: Neuropathy Disability Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of INCB086550 in Select Solid Tumors
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Urothelial Cancer|Renal Cell Carcinoma|Hepatocellular Carcinoma|Melanoma
Interventions: DRUG: INCB086550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Prophylaxis of Lyme Disease Using Permethrin Treated Clothes
Status: TERMINATED
Conditions: Lyme Disease
Interventions: OTHER: Permethrin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of VR942 in Healthy Volunteers and Patients With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: VR942 delivered via a Vectura Dry Powder Inhaler|DRUG: Placebo delivered via a Vectura Dry Powder Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Point of Care Ultrasound to Confirm Endotracheal Tube Cuff Position in Relationship to the Cricoid in Pediatric Population.
Status: COMPLETED
Conditions: Endotracheal Tube|Cricoid Cartilage|Ultrasound
Interventions: DIAGNOSTIC_TEST: Ultrasound of the airway
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetic Factors of Erectile Dysfunction Degree and Response to Tadalafil Treatment in Patients With Diabetes
Status: RECRUITING
Conditions: Erectile Dysfunction With Diabetes Mellitus
Interventions: DRUG: Tadalafil 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Olfactory Dysfunction in Seasonal Allergic Rhinitis
Status: TERMINATED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Mometasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced Castration Resistant Prostate Carcinoma With Limited Bone Metastases (α-RT)
Status: UNKNOWN
Conditions: Prostate Carcinoma
Interventions: DRUG: Radium-223 dichloride|OTHER: Conventional or high dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation
Status: COMPLETED
Conditions: Preterm Birth
Interventions: OTHER: Conventional Physiotherapy|OTHER: Prolonged slow exhalation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platinum-based Chemotherapy Plus Immune Checkpoint Inhibitors for EGFR/ALK/ROS1 Mutant Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed, Cisplatin, Bevacizumab Plus Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Medications to Treat Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Induction Cetuximab (IM-C225), Gemcitabine, and Oxaliplatin in Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cetuximab|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INCB053914 and Pomalidomide With Dexamethasone for Relapsed and/or Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Refractory Multiple Myeloma|Relapse Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: INCB053914 50 mg bis in die (BID)|DRUG: INCB053914 65 mg BID|DRUG: INCB053914 80 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Preoperative Docetaxel or Cisplatin (CDDP) + Docetaxel for C-stage IB-II Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Pulmonary Neoplasms
Interventions: DRUG: Preoperative docetaxel-cisplatin combination chemotherapy|DRUG: Preoperative docetaxel monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Designed Empathy Course
Status: NOT_YET_RECRUITING
Conditions: Smoking Cessation|Nursing Education
Interventions: BEHAVIORAL: A designed empathy intervention|BEHAVIORAL: Smoking cessation counseling tutorial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gemcitabine/Cisplatin Versus Gemcitabine/Epirubicin for Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Green Tea Supplementation in Older Adult Women
Status: RECRUITING
Conditions: Female|Older Adults|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Green tea (Camellia sinensis) 1000 mg as extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of Diltiazem and MK-5684 in Healthy Adult Male Participants (MK-5684-011)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: MK-5684|DRUG: Prednisone|DRUG: Fludrocortisone acetate|DRUG: Diltiazem hydrocholoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Efficacy Safety and Immunogenicity of ADL-018 With XOLAIR (Omalizumab) in Adults With Chronic Idiopathic Urticaria
Status: RECRUITING
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: Omalizumab Injection|DRUG: Xolair Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)
Interventions: BIOLOGICAL: basiliximab|BIOLOGICAL: WT1 126-134 peptide vaccine|DRUG: Montanide ISA 51 VG|DRUG: poly ICLC|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gamification in Enhancing User Engagement
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Gamification|Assistive Technology
Interventions: DEVICE: The MapHabit system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: L-Cysteine in Peritoneal Dialysis
Status: COMPLETED
Conditions: Uremia
Interventions: DIETARY_SUPPLEMENT: L-cysteine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Efficacy of Vardenafil in the Treatment of Subjects With Symptomatic Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Piezosurgical Buccal Plate Repositioning Technique for Horizontal Alveolar Ridge Augmentation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: OTHER: silica-calcium phosphate nanocomposite SCPC|OTHER: freezed dried bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy (FLAC) Combined With Granulocyte-Macrophage Colony Stimulating Factor in Locally Advanced and Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: FLAC with GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Doxorubicin, and Cyclophosphamide in Treating Women With Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]BMS-986419 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]BMS-986419
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on the Application and Mechanism of New Biological Probes in Biomedicine
Status: COMPLETED
Conditions: Tumors|Cardiovascular Diseases|Respiratory System Diseases|Digestive System Diseases|Endocrine System Diseases|Metabolic Diseases|Immune System Diseases|Urinary System Diseases|Nervous System Diseases|Blood Diseases|Infectious Diseases
Interventions: DIAGNOSTIC_TEST: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assess the Safety and Pharmacokinetics of Ascending, Multiple Oral Doses of SPD489 in Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer
Status: TERMINATED
Conditions: Advanced Solid Tumors (Excluding Prostate Cancer)|Ovarian Cancer
Interventions: DRUG: Elimusertib (BAY1895344)|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Positive Psychological Interventions for Patients With Multiple Sclerosis
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis
Interventions: OTHER: Positive Psychological Intervention Program|OTHER: Writing Daily Routines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: T-Reg Cell Kinetics, Stem Cell Transplant, REGALE
Status: TERMINATED
Conditions: Leukemia|Hodgkin Lymphoma|Non Hodgkin Lymphoma|Myeloproliferative Disorders
Interventions: DRUG: ARA C|DRUG: Cyclophosphamide|DRUG: MESNA|RADIATION: Total Body Irradiation (TBI)|BIOLOGICAL: Campath-1h|PROCEDURE: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Breast Cancer|Bone Metastasis
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission Tomography in Patients With Mild-to-Moderate Alzheimer's Disease and Cognitively Normal Elderly Subjects (Study MK-0000-068)(COMPLETED)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: OTHER: MRI|OTHER: FDG-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Enhanced External Counterpulsation to Treat Long COVID-19 Fatigue
Status: RECRUITING
Conditions: Post-Acute COVID-19 Syndrome
Interventions: PROCEDURE: Enhanced external counterpulsation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Followed by Surgery Versus Concurrent Chemoradiation in Carcinoma of the Cervix
Status: UNKNOWN
Conditions: Cancer of Cervix
Interventions: DRUG: NACT|PROCEDURE: Radical abdominal hysterectomy (class III), BPLND & lower para aortic lymph node sampling|DRUG: Inj.Cisplatin|RADIATION: Concurrent chemo radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electro-Acupuncture on Blood Pressure
Status: RECRUITING
Conditions: Hypertension
Interventions: PROCEDURE: Electro-acupuncture control|PROCEDURE: Electro-acupuncture test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus
Status: COMPLETED
Conditions: Super-refractory Status Epilepticus
Interventions: DRUG: SAGE-547
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Levocetirizine Dihydrochloride Tablets 5 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting State
Interventions: DRUG: Levocetirizine Dihydrochloride 5 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preop Dexmedetomidine Attenuates Haemodynamic Responses to Hydrodissection
Status: COMPLETED
Conditions: Robotic Thyroidectomy
Interventions: DRUG: DXM + Propofol|DRUG: Saline + Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of Paclitaxel Loaded Polymeric Micelle in Patients With Taxane-Pretreated Recurrent Breast Cancer
Status: UNKNOWN
Conditions: Recurrent Breast Cancer
Interventions: DRUG: Paclitaxel loaded Polymeric micelle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Insoles as Conservative Treatment for Medial Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Foot deformity correcting insoles|DEVICE: Lateral wedge insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part, Single-Blind, Phase 3 Study Evaluating the Efficacy and Safety of Patiromer for the Treatment of Hyperkalemia (OPAL)
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)|Hyperkalemia (HK)
Interventions: DRUG: Patiromer|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants
Status: TERMINATED
Conditions: Prematurity|Respiratory Distress Syndrome|Patent Ductus Arteriosus
Interventions: DRUG: Survanta (beractant)|DRUG: Curosurf (poractant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Caries in Preschoolers: Testing a Unique Service Delivery Model in American Indian Head Start Programs
Status: COMPLETED
Conditions: Fluoride Varnish and Oral Health Promotion|Usual Care
Interventions: DEVICE: Fluoride varnish|BEHAVIORAL: Oral health education|OTHER: Dental services delivered by the Indian Health Service.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)
Status: TERMINATED
Conditions: Alzheimer's Disease|Dementia
Interventions: DRUG: MK-0249 7.5 mg|DRUG: MK-0249 25 mg|DRUG: Donepezil 5mg|DRUG: Placebo to MK-0249|DRUG: Placebo to Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Tolerability of INCB000928 in Participants With Myelodysplastic Syndromes or Multiple Myeloma
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Multiple Myeloma|Anemia
Interventions: DRUG: INCB000928
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Two Different Types of Manual Techniques to an Exercise Program for the Management of Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Intervention 1 Exercise|OTHER: Intervention 2 Exercise and INIT|OTHER: Intervention 3 Exercise and SMT|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling Telehealth Models to Improve Co-morbid Diabetes and Hypertension in Immigrant Populations (Phase II)
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus Type II|Hypertension
Interventions: BEHAVIORAL: Integrated CHW Intervention|BEHAVIORAL: CHW Session 1 Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasias
Status: UNKNOWN
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: ESD|PROCEDURE: TAMIS|PROCEDURE: TEO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging (fMRI) Investigation Into Compulsivity in Anorexia
Status: COMPLETED
Conditions: Anorexia Nervosa in Remission (Disorder)|Compulsive Behavior
Interventions: OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments
Status: TERMINATED
Conditions: Hypercholesterolemia|Type 2 Diabetes|Hypertension
Interventions: DRUG: Pravastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Intervention to Reduce Delirium After Cardiac Surgery
Status: COMPLETED
Conditions: Delirium|Congenital Heart Disease|Coronary Artery Disease|Heart Valve Disease
Interventions: PROCEDURE: Remote ischemic pre-conditioning|BEHAVIORAL: Delirium Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Ajwa Derived Polyphenols in Dyslipidaemias
Status: UNKNOWN
Conditions: Dyslipidemias|Hyperglycemia|Liver Dysfunction|Oxidative Stress|Hemoglobin SC|Anemia
Interventions: DIETARY_SUPPLEMENT: Ajwa Date (phoenix dactylifera)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flower Print Activity Applied to the Elderly in the Nursing Home
Status: COMPLETED
Conditions: Elderly|Gardening|Anxiety|Nursing Caries
Interventions: OTHER: flower printing activities for the elderly|OTHER: Routine activities in nursing home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Need to be Needed (N2BN) Intervention
Status: NOT_YET_RECRUITING
Conditions: Loneliness|Social Isolation
Interventions: BEHAVIORAL: Need to Be Needed Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Education Training on Parents With Autism Based on Denver Model
Status: NOT_YET_RECRUITING
Conditions: Autism|Parents
Interventions: BEHAVIORAL: Educational training based on the Denver model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Near Infrared Light Therapy for Alzheimer's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Mild to Moderate Alzheimer's Disease
Interventions: DEVICE: treatment group-Device: NirsCure - Active NirsCure - Active settings|DEVICE: placebo group-Device: NirsCure - Sham NirsCure - Sham settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, Adult|Myelodysplastic Syndrome(MDS)|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Fludarabine and Busulfan|DRUG: Fludarabine and Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIBF 1120 Versus Bevacizumab in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: BIBF 1120|DRUG: BIBF 1120|DRUG: mFolfox|DRUG: Bevacizumab|DRUG: mFolfox 6|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Head Elevated Positioning Device on Position, Height and Depth of the Cricothyroid Membrane in Morbidly Obese Pregnant Women in the Third Trimester.
Status: COMPLETED
Conditions: Airway Complication of Anesthesia
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lactocare Baby Drops in Infants Colic
Status: COMPLETED
Conditions: Infant Colic
Interventions: DIETARY_SUPPLEMENT: Drops with lactobacilli and vitamin D3|DIETARY_SUPPLEMENT: Drops with vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study DR-2031 for the Treatment of Hot Flashes in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Cyproterone acetate 5|DRUG: Placebo|DRUG: Cyproterone acetate 15|DRUG: Cyproterone acetate 25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation, TBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gadovist 75% Standard Dose to Dotarem at Full Standard Dose
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadoterate (Dotarem/Clariscan)|DRUG: Gadobutrol (Gadavist/Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC