pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Validation of the IgA1 Detection Method With Gradient Glycosylation by Mass Spectrometry as a Potential Marker of Renal Involvement in Pediatric Rheumatoid Purpura
Status: COMPLETED
Conditions: Rheumatoid Purpura|Pediatric ALL
Interventions: OTHER: Mass Sepctrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of PRC-4016 in Subjects With Mixed Dyslipidemia
Status: TERMINATED
Conditions: Dyslipidemia
Interventions: DRUG: PRC-4016|DRUG: Placebo|DRUG: Statins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42847922 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42847922 5 mg|DRUG: JNJ-42847922 10 mg|DRUG: JNJ-42847922 20 mg|DRUG: JNJ-42847922 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced HER2+Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Alpelisib matching Placebo|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Post-operative Treatment on Intraocular Pressure Post-SLT on Patients With Primary Open-angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Inflammatory Response
Interventions: PROCEDURE: Selective Laser trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402)
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: OTHER: General condition|OTHER: Blood pressure|OTHER: Patient Reported Outcome|OTHER: Clinical findings|OTHER: Hematology/blood chemistry|OTHER: Coagulation and fibrinolysis system|OTHER: Urinalysis|OTHER: Medication check|OTHER: Adverse event|OTHER: Thyroid function test|OTHER: Contrast-enhanced torso CT|OTHER: Brain MRI|DRUG: Dexamethasone|DRUG: Regorafenib|DRUG: Placebo|DRUG: Proton pump inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Zampilimab in Adult Kidney Transplant Recipients With Chronic Allograft Injury
Status: TERMINATED
Conditions: Chronic Allograft Injury
Interventions: DRUG: Zampilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Treatment Flow and Prognosis ofTraumatic Thoracic Aortic Injuries：A Multi-center Retrospective Analysis in Zhejiang Province During 11 Years
Status: COMPLETED
Conditions: Severe Trauma|Blunt Thoracic Aortic Injury|Interventional Therapy|Treatment Protocal
Interventions: BIOLOGICAL: Referral information
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Camrelizumab Combined With Apatinib 、XELOX 、RFA in the Treatment of Liver Metastases of Colorectal Cancer
Status: UNKNOWN
Conditions: Hepatic Metastasis of Colorectal Cancer
Interventions: DRUG: Camrelizumab|DRUG: Apatinib Mesylate|DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Administration of Tamsulosin for Prevention of Post Operative Urinary Retention in Males Undergoing Elective Inguinal Hernia Repair
Status: COMPLETED
Conditions: Postoperative Urinary Retention
Interventions: DRUG: Tamsulosin|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 3VM for Treatment of Chronic Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Arthritis, Degenerative
Interventions: DRUG: Experimental: 3VM1001 active 2g Cream 3 times daily|DRUG: Experimental: 3VM1001 active 3g Cream 3 times daily|DRUG: Experimental: 3VM1001 active 3g Cream 4 times daily|DRUG: Placebo: 3VM1001 vehicle 2g Cream 3 times daily|DRUG: Placebo: 3VM1001 vehicle 3g Cream 3 times daily|DRUG: Placebo: 3VM1001 vehicle 3g Cream 4 times daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurally Adjusted Ventilatory Assist (NAVA) in NonInvasive Ventilation (NIV)
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Neurally Adjusted Ventilatory Assist in Non Invasive Ventilation (Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Optic Neuritis|Transverse Myelitis|Acute Brainstem/Cerebellar Syndrome
Interventions: DRUG: interferon beta 1a 30 ug IM once weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5
Status: TERMINATED
Conditions: Kidney Diseases
Interventions: DRUG: Lanthanum carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Healthy Subjects in Fasted and Fed State
Interventions: DRUG: Dapagliflozin/metformin XR 5/500mg|DRUG: Dapagliflozin/metformin XR 5/500 mg|DRUG: Dapagliflozin/metformin XR 5/500mg|DRUG: Dapagliflozin/metformin XR 5/500mg|DRUG: Dapagliflozin/metformin XR 10/1000mg|DRUG: Dapagliflozin/metformin XR 10/1000mg|DRUG: Dapagliflozin/metformin XR 10/1000mg|DRUG: Dapagliflozin/metformin XR 10/1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Chronic|Opioid Dependence|Opioid Use|Inflammation Chronic
Interventions: DIETARY_SUPPLEMENT: Root.Health Dietary Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Effects of Kinesio and Dynamic Tapings in Postpartum Women With Pelvic Girdle Pain
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: DEVICE: Kinesio taping|DEVICE: Dynamic taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Pulpitis
Interventions: DRUG: local anaesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: neoantigen tumor vaccine with or without PD-1/L1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Movement Before and After Stellate Ganglion Block : A Ultrasonographic Study
Status: COMPLETED
Conditions: Head Pain|Neck Pain|Shoulder Pain|Arm Pain|Neural Sensory Hearing Loss
Interventions: PROCEDURE: M-mode ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Intraoperative Normal Saline vs Lactated Ringer on Outcomes in Pediatric Liver Transplantation
Status: UNKNOWN
Conditions: Biliary Atresia Intrahepatic Syndromic Form
Interventions: DRUG: Lactated Ringer|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pulmonary Function and Efficacy of Different Nerve Block Catheters for Shoulder Surgery
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: PROCEDURE: Continuous Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Single Dose-Escalation Safety Study of Human Glucocerebrosidase (prGCD)
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: DRUG: Human Glucocerebrosidase (prGCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Family or Care-givers of Very Old ICU-survivors, Trajectories and 6 Months' Outcome in the Very Old.
Status: WITHDRAWN
Conditions: Functionally-Impaired Elderly|Caregivers|PTSD|Depression, Anxiety|Intensive Care Unit Syndrome
Interventions: OTHER: Telephone support on demand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of a Mind Body Program for Obese Knee Osteoarthritis Patients With Comorbid Depression
Status: COMPLETED
Conditions: Knee Osteoarthritis|Obesity|Depression
Interventions: BEHAVIORAL: GetHealthy-OA|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The BLIS Study: a Feasibility Study Assessing Compliance, Acceptability and Colonisation With Different Dosing Regimens of the Probiotic Supplement Streptococcus Salivarius K12 (Bactoblis®) in Adults
Status: UNKNOWN
Conditions: Sore Throat|Tonsillitis|Pharyngitis
Interventions: DIETARY_SUPPLEMENT: probiotic supplement Streptococcus salivarius K12 (Bactoblis®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Neovascular Age-related Macular Degeneration|Wet Macular Degeneration|BRVO - Branch Retinal Vein Occlusion|Diabetic Macular Edema
Interventions: BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety and Efficacy of UCART123v1.2 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: BIOLOGICAL: UCART123v1.2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Using Volunteers to Implement a Cognitive Stimulation Program in Two Long-Term Care Homes
Status: COMPLETED
Conditions: Impaired Cognition|Geriatric Disorder|Learning Disorders|Age-Related Memory Disorders|Impairment of Attention
Interventions: OTHER: Cognitive stimulation program|OTHER: Standard Friendly Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Inhaled Iloprost for the Treatment of Pulmonary Hypertension After Repair of Congenital Heart Disease
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: iloprost nebuliser solution|DRUG: iloprost nebuliser solution|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stemless and Stemmed Shoulder Arthroplasty for Osteoarthritis
Status: RECRUITING
Conditions: Glenohumeral Osteoarthritis
Interventions: PROCEDURE: Shoulder arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy And Safety of IVIEW-1201 In the Treatment of Fungal Keratitis
Status: NOT_YET_RECRUITING
Conditions: Fungal Keratitis
Interventions: DRUG: IVIEW-1201|DRUG: NATACYN®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Lenvatinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nasonex® for the Treatment of Nasal Polyps in Pediatric Subjects Between Ages of 6 and Less Than 18 Years Old (P04292)
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Mometasone Furoate Nasal Spray (MFNS)|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Secondary Distress in Violence Researchers: a Randomised Trial of the Effectiveness of Group Debriefings.
Status: COMPLETED
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Group Debriefing|BEHAVIORAL: leisure activity (film showing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Urinary Kallidinogenase in the Treatment of Acute Ischemic Stroke Combined With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Type 2 Diabetes
Interventions: DRUG: Urinary Kallidinogenase for injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga PSMA 11 PET/MRI and 68Ga RM2 PET/MRI for Biopsy Guidance in Patients With Suspected Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga RM2|DRUG: 68Ga-PSMA-11|DEVICE: Investigational PET scanner coils and software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of COMBIVENT® HFA as Compared to COMBIVENT® CFC and Placebo HFA in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: COMBIVENT® HFA-MDI|DRUG: COMBIVENT® CFC-MDI|DRUG: Placebo HFA-MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise Intensity, Glycemic Control and Abdominal Fat in People With Type 2 Diabetes: A Pilot Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Traditional Intensity Exercise|BEHAVIORAL: High Intensity Interval Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Orifice Configuration (Six-hole Versus End-hole) on Post-operative Analgesia After Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Pain
Interventions: COMBINATION_PRODUCT: lidocaine and ropivacaine injection through catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Palliative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Stem Cell Transplant
Interventions: OTHER: Palliative Care Intervention|OTHER: Standard Transplant Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia
Status: COMPLETED
Conditions: Primary Ciliary Dyskinesia
Interventions: DRUG: VX-371|DRUG: Hypertonic Saline|DRUG: Placebo (0.17% saline)|DRUG: VX-371 + HS|DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence to Blood Pressure Diaries With Personalized Visuals
Status: COMPLETED
Conditions: Neurovascular Disorder
Interventions: OTHER: Inclusion of patient-provided pictures into blood pressure diaries|OTHER: Conventional blood pressure diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Exercise on Hand Function, Daily Activities Performance and Quality of Life of SLE' Patients
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Arthralgia
Interventions: BEHAVIORAL: HAND EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Anerning Particle for the Treatment of Childhood Community-acquired Pneumonia
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Anerning particle|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Fondaparinux as Post Partum Thromboprophylaxis
Status: COMPLETED
Conditions: Thromboembolism in the Puerperium
Interventions: DRUG: Fondaparinux 2.5Mg/0.5Ml Inj Syr
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: JNJ-77242113|DRUG: JNJ-77242113 Matching Placebo|DRUG: Deucravacitinib|DRUG: Deucravacitinib Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biopace Study: Biventricular Pacing for Atrioventricular Block to Prevent Cardiac Desynchronization
Status: COMPLETED
Conditions: Atrioventricular Block|Ventricular Dysfunction
Interventions: DEVICE: Biventricular Pacing|DEVICE: RV Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy
Status: RECRUITING
Conditions: Pain, Postoperative|Spine Surgery
Interventions: DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Inspiratory Muscle Training on Type 2 Diabetes Mellitus Patients With Inspiratory Muscle Weakness
Status: COMPLETED
Conditions: Diabetes Complications|Inspiratory Muscle Weakness
Interventions: BEHAVIORAL: Inspiratory muscle training|BEHAVIORAL: Inpiratory muscle training placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Accuracy of Computer Guided Versus Conventional Segmental Sandwich Osteotomy With Immediate Implant Placement in Vertically Deficient Anterior Maxilla
Status: UNKNOWN
Conditions: Sandwich Osteotomy
Interventions: PROCEDURE: computer guided sandwich osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARrest RESpiraTory Failure From PNEUMONIA
Status: RECRUITING
Conditions: Pneumonia|Hypoxemia|Acute Respiratory Failure|COVID-19 Pneumonia
Interventions: DRUG: Inhaled budesonide and formoterol|DRUG: Inhaled placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Simvastatin Treatment in Organ Transplantation
Status: COMPLETED
Conditions: Heart Failure|Respiratory Failure|Liver Failure|Kidney Failure|Transplantation
Interventions: DRUG: Simvastatin 80mg|DRUG: Control Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Thumb-tack Needle Treatment for Diminished Ovarian Reserve
Status: RECRUITING
Conditions: Diminished Ovarian Reserve
Interventions: DEVICE: thumb-tack needle|DEVICE: sham thumb-tack needle|OTHER: Basic gynecological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation
Status: RECRUITING
Conditions: Advanced NSCLC|Metastatic Lung Cancer
Interventions: DRUG: Adagrasib oral dose of 400 mg twice daily tablets|COMBINATION_PRODUCT: Pembrolizumab|COMBINATION_PRODUCT: Chemotherapy: Pemetrexed|COMBINATION_PRODUCT: Cisplatin/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Swedish Massage Therapy on Cancer-related Fatigue in Cancer Survivors
Status: COMPLETED
Conditions: Cancer Related Fatigue
Interventions: OTHER: Swedish massage therapy|OTHER: Light touch therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of 99mTc- EDDA - HYNIC -TOC Kits for Diagnosis of Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: OTHER: 99m Tc - HYNIC -TOC EDDA and 111In - DTPA-octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: BGF MDI 320/28.8/9.6 μg|DRUG: BGF MDI 320/14.4/9.6 μg|DRUG: BFF MDI 320/9.6 μg|DRUG: BFF pMDI 320/9 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Protocol for Announcing Decision of Withholding and Withdrawing Life-sustaining Treatments on the Stress of the Relatives in the Emergency Departments
Status: NOT_YET_RECRUITING
Conditions: End of Life
Interventions: BEHAVIORAL: Training of professionals according to the DISCUSS announcement protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of STA-1 Capsule in Patients With Vascular Dementia (Marrow-Sea Deficiency)
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: STA-1|DRUG: Ergoloid Mesylates tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II|Diabetes Mellitus, Non Insulin Dependent
Interventions: DRUG: Canagliflozin (JNJ-28431754)|DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Early TIPS" Versus Glue Obliteration to Prevent Rebleeding From Gastric Varices
Status: COMPLETED
Conditions: Bleeding Gastric Varices|Cirrhosis
Interventions: PROCEDURE: Transjugular Portosytemic Shunt (TIPS)|PROCEDURE: glue obliteration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Adult Acute Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone / Prednisolone|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Granulocyte-Colony-Stimulating Factor|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Rituximab|DRUG: HDARAC|DRUG: Vincristine|DRUG: Depocyte|DRUG: Asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketones, SGLT2, HFrEF
Status: RECRUITING
Conditions: Type2diabetes|Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Empagliflozin 25 MG Oral Tablet|DRUG: Placebo|DRUG: Acipimox 250 Mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|Sleep Apnea|Sleep Apnea Syndromes|Apnea|Respiration Disorder|Respiratory Tract Disease|Dyssomnia|Sleep Disorders, Intrinsic|Sleep Wake Disorders|Nervous System Diseases|Hypnotics and Sedatives|Central Nervous System Depressants|Propofol|Midazolam|Physiological Effects of Drugs|General Anesthetics
Interventions: DEVICE: Drug-induced sleep endoscopy|DEVICE: Natural sleep endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety Study of Inactivated Subunit H5N1 Influenza Vaccine in Prior Recipients of Live Attenuated H2N2, H6N1 and H9N2 Influenza Vaccines and in H5N1 and Live Attenuated Vaccine Naïve Individuals
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H5N1 pISV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Sham Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Food as Medicine Interventions for Food Insecure Postpartum Women in Central Texas
Status: RECRUITING
Conditions: Food Insecurity in Post Partum Women
Interventions: OTHER: FBM-In person|OTHER: FBM-Virtual|OTHER: home delivered food boxes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)
Status: RECRUITING
Conditions: Advanced Gastrointestinal Tumors
Interventions: BIOLOGICAL: LCAR-G08 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Test Use of a Decision Aid in a Clinical Visit to Help Patients Choose a Diabetes Medication
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Diabetes Medication Choice Cards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant Recipients
Status: COMPLETED
Conditions: Transplant Rejection|Renal Transplantation
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Human Embryonic Development Using Single Medium With and Without the Addition of Antioxidants
Status: COMPLETED
Conditions: Culture Media|Blastocyst|Antioxidants|Embryo|Human
Interventions: BIOLOGICAL: Acetyl-L-carnitine (ALC), N-acetyl-L-cysteine (NAC) and α-lipoic acid (ALA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stearidonic Acid and Lipid Metabolism
Status: COMPLETED
Conditions: Lipid Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Echium oil (SDA-rich oil)|DIETARY_SUPPLEMENT: high-oleic acid sunflower oil (HOSO) (low in SDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia
Status: COMPLETED
Conditions: Sickle Cell Disease|Chronic Kidney Disease|Pulmonary Hypertension
Interventions: DRUG: Erythropoietin and Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of the Bioavailability of Fenofibric Acid and Rosuvastatin From ABT-143 Relative to That From the Coadministration of ABT-335 (Fenofibric Acid) and Rosuvastatin Calcium
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABT-143|DRUG: ABT-335|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Responses Induced by Different Licensed Influenza Vaccines
Status: COMPLETED
Conditions: Immune Response
Interventions: BIOLOGICAL: Flulaval|BIOLOGICAL: Fluvirin|BIOLOGICAL: Fluzone|BIOLOGICAL: Fluarix|BIOLOGICAL: Afluria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Effect of Multiple Weight Management Modalities for Chronic Disease Risk Reduction in a Clinical Setting
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Low-Carbohydrate Diet|BEHAVIORAL: Intermittent Energy Restriction|BEHAVIORAL: Hunger Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Biomarkers in Blood & Tissue Samples From Patients With Colorectal Cancer or Polyps & Patients Without Polyps
Status: COMPLETED
Conditions: Colorectal Cancer|Healthy, no Evidence of Disease|Precancerous Condition
Interventions: GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|GENETIC: protein expression analysis|GENETIC: proteomic profiling|OTHER: gas chromatography|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 11C-Acetate PET/CT Non-FDG-Avid Tumors
Status: UNKNOWN
Conditions: Soft Tissue Sarcomas|Thyroid Cancer|Lung Cancer|Indolent Lymphoma|Neuroendocrine Tumors|GIST|Uterine Malignancies|Carcinoma, Hepatocellular|Carcinoma, Lobular|Teratoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer
Status: UNKNOWN
Conditions: Early Gastric Cancer
Interventions: OTHER: an educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Colchicine on Platelet Function Profiles in Patients With Stable Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Colchicine 0.5 MG oral tablet twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conscious Sedation vs General Anesthesia in TAVR Patients
Status: WITHDRAWN
Conditions: Aortic Stenosis
Interventions: PROCEDURE: General Anesthesia|PROCEDURE: Conscious Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Airflow Limitation in Chronic Obstructive Pulmonary Disease (COPD) be Reversible by Drugs?
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Macrolid, Theophylline, Inhaler Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Ondansetron and Combined Ondansetron and Betahistine on Postoperative Nausea and Vomiting After Gynecological Laparoscopy
Status: COMPLETED
Conditions: Nausea and Vomiting
Interventions: DRUG: ondansetron|DRUG: ondansetron-betahistine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Inhaled Budesonide in Transient Tachypnea of the Newborn
Status: UNKNOWN
Conditions: Respiratory Distress
Interventions: OTHER: Inhaled corticosteroids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension
Status: UNKNOWN
Conditions: Cirrhosis, Liver|Acute-On-Chronic Liver Failure|Shock, Septic|Shock Hypovolemic
Interventions: DRUG: 20% albumin|DRUG: Balanced salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy
Status: COMPLETED
Conditions: Partial Pneumonectomy Under Lateral or Posterolateral Thoracotomy.
Interventions: DRUG: Hypothetica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cunermuspir on Energy, Strength, and Fatigue in Patients With Nerve or Muscle Pain
Status: COMPLETED
Conditions: Neuralgia|Myalgia
Interventions: DRUG: Cunermuspir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Transplantation in Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Severe Aplastic Anemia
Interventions: OTHER: MSD-HSCT|OTHER: HFD-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma vs Viscosupplementation in the Treatment of Knee Articular Degenerative Pathology
Status: COMPLETED
Conditions: Knee Chondropathy|Osteoarthritis, Knee
Interventions: BIOLOGICAL: PRP|DEVICE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting Occult Proximal Humeral Neck Fractures Through CT and MRI Tests of Patients With Greater Tuberosity Fractures
Status: UNKNOWN
Conditions: Humeral Greater Tuberosity|Humeral Fractures/ Proximal|Fractures/ Occult
Interventions: DIAGNOSTIC_TEST: CT and MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insulinotropic Effect of GIP and GLP-1 Before and After Reduced Glucose Tolerance
Status: COMPLETED
Conditions: Insulin Resistance|Deteriorated Glucose Homeostasis|Inactivity
Interventions: BEHAVIORAL: Steroid hormone|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Controlled Trial of Silymarin in Asthma
Status: WITHDRAWN
Conditions: Atopic Asthma
Interventions: DRUG: Oral Silymarin|DRUG: Oral Silymarin, maintenance dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors
Status: RECRUITING
Conditions: PD-L1-selected Solid Tumors
Interventions: DRUG: Tiragolumab and Atezolizumab IV FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Independent Living in Frail Older Adults by Improving Cognition and Gait Ability and Using Assistive Products
Status: COMPLETED
Conditions: Frailty|Cognition|Mild Cognitive Impairment
Interventions: OTHER: Combined Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Pharmacokinetics of CC-220 in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared With Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: CC-220
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentoxiphylline and Vitamin E Versus Vitamin E in Patients With Non- Alcoholic Steatohepatitis
Status: WITHDRAWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: DRUG: pentoxiphylline and Vitamin E|DRUG: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
Status: RECRUITING
Conditions: Peripheral Artery Disease|Overweight or Obesity
Interventions: BEHAVIORAL: Weight loss|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial
Status: RECRUITING
Conditions: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)|Surfactant Dysfunction|Infant
Interventions: OTHER: Prone positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Anemia, Refractory, With Excess of Blasts
Interventions: DRUG: IGF/MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Acute Palliative Care Consultation in Critically Ill Patients
Status: UNKNOWN
Conditions: Multiple Organ Failure|End Stage Cardiac Failure|End Stage Chronic Obstructive Airways Disease|Chronic Kidney Disease Stage 5|Hepatic Encephalopathy|Sepsis|Dementia|Multiple Sclerosis|Parkinson's Disease|In-Hospital Cardiac Arrest|Solid Organ Cancer
Interventions: OTHER: Early order of palliative care consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Convernsion Therapy Using S1/Paclitaxel Chemotherapy Plus Apatinib in Unresectable Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: S1/Paclitaxel chemotherapy plus Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of Sentinel Lymphnode Biopsy After Neoadjuvant Chemotherapy Cancer Patients With Radiologically Positive Axillary Lymph Nodes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Sentinel lymph node biopsy|DRUG: Neoadjuvant chemotherapy|PROCEDURE: complete axillary lymph node dissection|PROCEDURE: positron emission tomography and ultrasonogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-P15-041 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Prostate Bone Metastasis
Status: UNKNOWN
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: 68Ga-PSMA-11|DRUG: 68Ga-P15-041
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-term Intravenous Fluids for Prevention of Post-ERCP Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Post-ERCP Acute Pancreatitis
Interventions: OTHER: Intravenous Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Pharmacokinetic (PK) Profile of Bazedoxifene (BZA) in 2 BZA/Conjugated Estrogen Forms
Status: COMPLETED
Conditions: Postmenopause
Interventions: DRUG: Bazedoxifene/conjugated estrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbidopa/Levodopa Versus Carbidopa/Levodopa/Entacapone on Markers of Event Related Potentials (ERPs) in Patients With Idiopathic Parkinson's Disease (PD) and End-of-dose Wearing Off
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: carbidopa/levodopa|DRUG: Carbidopa/Levodopa/Entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canola Oil Multicentre Intervention Trial (COMIT)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Canola Oil|DIETARY_SUPPLEMENT: High Oleic Acid + DHA Canola Oil|DIETARY_SUPPLEMENT: High Oleic Acid Canola Oil|DIETARY_SUPPLEMENT: Flax Oil|DIETARY_SUPPLEMENT: Safflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Patient Reported Outcomes Reported Via PC / Tablet Home Versus Touch Screen at Hospital Among Patients With Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Axial Spondyloarthritis
Interventions: OTHER: Reporting of patient reported outcome measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis|Arthritis, Rheumatoid|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases|Connective Tissue Diseases|Autoimmune Diseases
Interventions: PROCEDURE: Magnetic resonance imaging (MRI)|OTHER: Conventional biochemical and clinical examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Use of the Vaccine Against Herpes Zoster/Shingles at NYULMC and Bellevue Hospital
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: OTHER: Choosing to receive the vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: bupivacaine liposome injectable suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Pain Relief in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Chronic Pain
Interventions: DRUG: Duloxetine|DRUG: Remifentanil|DRUG: Placebo (for Remifentanil)|DRUG: Placebo (for Duloxetine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Balanced Salt Solution During Cataract Surgery
Status: RECRUITING
Conditions: Fuchs Dystrophy|Cataract
Interventions: DRUG: BSS Plus|DRUG: BSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE