pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease
Status: SUSPENDED
Conditions: Lung Non-Small Cell Carcinoma|Pleural Disorder
Interventions: DRUG: Porfimer Sodium|PROCEDURE: Video-Assisted Thoracic Surgery|DRUG: Photodynamic Therapy|DEVICE: Intraoperative PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Alogliptin and Insulin in the Treatment of Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin and insulin|DRUG: Alogliptin and insulin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer|Gastro-esophageal Junction (GEJ) Cancer
Interventions: DRUG: Zolbetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant + Dexamethasone|DRUG: Ondansetron + Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Postprandial Insulin Administration of Faster-acting Insulin Analogue Versus Pre-prandial Administration of Acting-insulin Analogue in Cystic Fibrosis Related Diabetes
Status: RECRUITING
Conditions: Cystic Fibrosis-related Diabetes
Interventions: DRUG: A-F-A-F (NovoRapid-FIASP-NovoRapid-FIASP)|DRUG: F-A-F-A (FIASP-NovoRapid-FIASP-NovoRapid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of CT Perfusion to Determine the Normalization Window Period in the Treatment of Advanced Primary Lung Adenocarcinoma With Endostar
Status: UNKNOWN
Conditions: Advanced Primary Lung Adenocarcinoma
Interventions: DRUG: endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: 18F-SF12051
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Validation of Programmable Drain Fluid Regulator to Reduce Morbidity, Care Requirements, and Improve Outcomes
Status: RECRUITING
Conditions: Pleural Effusion|Ascites
Interventions: DEVICE: EFFIDRAIN|DEVICE: Manual drainage system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Radiofrequency Ablation and Hypofractionated Proton Beam Radiation for Recurrent/Residual HCC
Status: COMPLETED
Conditions: Recurrent Small Hepatocellular Carcinoma|Residual Small Hepatocellular Carcinoma
Interventions: PROCEDURE: radiofrequency ablation|RADIATION: Proton beam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
Status: COMPLETED
Conditions: Humans|Urinary Incontinence|Male Urogenital Diseases|Prostatectomy|Erectile Dysfunction
Interventions: DEVICE: Intraoperative nerve monitoring,|PROCEDURE: standard of care robotic-assisted radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Jedi Grip vs. Double Operator Technique for Axillary Brachial Plexus Block
Status: COMPLETED
Conditions: Brachial Plexus Block|Ultrasound, Interventional
Interventions: PROCEDURE: conventional two-operator versus single operator using Jedi grip axillary brachial plexus blockage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: NAFLD|Low-free Sugar Dietary|Child Obesity
Interventions: BEHAVIORAL: Dietary intervention for low free sugars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study About Mechanism of Transcranial Magnetic Stimulation Treatment of Depression Using Medical Imaging
Status: UNKNOWN
Conditions: Depression
Interventions: RADIATION: Transcranial magnetic stimulation (TMS)|DRUG: antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IV Pancreatic Cancer
Interventions: BIOLOGICAL: VXM01|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina TM) as an Aid for Endoscopic Gastric Reduction.
Status: COMPLETED
Conditions: Weight Loss
Interventions: DEVICE: Endomina
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases
Status: COMPLETED
Conditions: Cancer|Bone Metastases
Interventions: DEVICE: F-18 PET bone scan|DEVICE: Tc-99m bone scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of 2nd Generation Anti-CEA Designer T Cells in Metastatic Breast Cancer
Status: SUSPENDED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Gene Modified T Cells|BIOLOGICAL: Gene Modified T Cells and Interleukin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Gold Standard EMS CPR Programs for 2% Improvement in Survival Rates of Out-of-Hospital Cardiac Arrest in a Metropolitan City
Status: TERMINATED
Conditions: Out-of-Hospital Cardiac Arrest
Interventions: PROCEDURE: Bundled EMS CPR approach including dispatcher-assisted CPR, 3-person team CPR, and feedback CPR monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease|Glycogen Storage Disease Type II
Interventions: BIOLOGICAL: Alglucosidase Alfa|DRUG: Methotrexate|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks: Comparison of 577 nm Versus 595 nm Wavelengths
Status: COMPLETED
Conditions: Port Wine Stains
Interventions: OTHER: Pulsed Dye Laser 577 nm|OTHER: Pulsed Dye Laser 595 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Patterns and Outcomes of Targeted Therapy and Immunotherapy Among BRAF-Positive Melanoma Patients Treated in the Adjuvant Setting and Among BRAF-Positive Metastatic Melanoma Patients With Low Tumor Burden
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Nivolumab|DRUG: Pembrolizumab|COMBINATION_PRODUCT: Dabrafenib+Trametinib|COMBINATION_PRODUCT: Ipilimumab+Nivolumab|COMBINATION_PRODUCT: Vemurafenib+Cobimetinib|COMBINATION_PRODUCT: Encorafenib+Binimetinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multifaceted Intervention to Improve Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: BEHAVIORAL: Enhanced Antimicrobial Stewardship Commitment and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib, Docetaxel, and Carboplatin in Treating Patients With Newly Diagnosed Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: carboplatin|DRUG: docetaxel|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns
Status: RECRUITING
Conditions: Persistent Pulmonary Hypertension of the Newborn|Echocardiography|Respiratory Disease
Interventions: DRUG: Nebulized nitroglycerine as adjunctive therapy|DRUG: conventional therapy for PPHN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures
Status: COMPLETED
Conditions: Partial Onset Seizures|Secondarily Generalized Seizures|Primary Generalized Tonic-Clonic Seizures
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Glycaemic Control in Patients With Type 2 Diabetes Mellitus Through Peer Support Instant Messaging
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Peer Support|Instant Messaging Service
Interventions: OTHER: Peer Support Intervention via Instant Messaging Service Tool (IMS-Tool)|OTHER: antidiabetic therapy according to the current guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Quality of Life Through the Routine Use of the Patient Concerns Inventory for Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Cancer of Head and Neck
Interventions: OTHER: Patient Concerns Inventory|OTHER: No Patient Concerns Inventory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics-pharmacodynamics and Safety of Dexmedetomidine in Children
Status: COMPLETED
Conditions: Intensive Care Unit|Postoperative Care
Interventions: DRUG: Dexmedetomidine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Failure|Graft vs Host Disease
Interventions: DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Madecassoside and 5 % Panthenol Cream in Post Photodynamic Therapy for Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: OTHER: Cream containing madecassoside and 5 % panthenol|OTHER: Daylight PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lofexidine for Inpatient Opiate Detox
Status: COMPLETED
Conditions: Opiate Addiction
Interventions: DRUG: Lofexidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D and Prebiotic Supplementation on Glucose Control During Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Glucose Intolerance During Pregnancy
Interventions: DRUG: Vitamin D3|DIETARY_SUPPLEMENT: Prebiotics|DIETARY_SUPPLEMENT: Prebiotics placebo|DIETARY_SUPPLEMENT: Vitamin D3 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)
Status: COMPLETED
Conditions: Chronic Sinusitis|Nasal Polyposis
Interventions: COMBINATION_PRODUCT: S8 Sinus Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trazodone Once a Day in Major Depression Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Trazodone|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AQUABEAM® Robotic System and Ultrasound Accessories
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DEVICE: AQUABEAM Robotic System|DEVICE: Apogee 2300 digital color doppler ultrasound imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Gait Disorders, Neurologic
Interventions: DRUG: memantine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OVSTAR TIL Trial (OVarian Cancer Co-STimulatory Antigen Receptor TIL Trial)
Status: WITHDRAWN
Conditions: Ovarian Cancer Metastatic
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine|DRUG: IL-2 (Proleukin)|GENETIC: Unmodified Tumour Infiltrating Lymphocytes (UTIL-01)|GENETIC: Gene modified Tumour Infiltrating Lymphocytes (CoTIL-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial to Evaluate Efficacy and Safety of a Tetravalent Dengue Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Dengue
Interventions: BIOLOGICAL: Dengue 1,2,3,4 (attenuated) vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: training|DRUG: nicotinic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gliosarcoma|Newly Diagnosed|Glioblastoma
Interventions: DRUG: Selinexor|DRUG: Temozolomide|RADIATION: Generic Radiation therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification
Status: NOT_YET_RECRUITING
Conditions: Radiculopathy Lumbar|Low Back Pain|Disc Herniation|Injections, Epidural
Interventions: PROCEDURE: Transforaminal Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLUtEus Maximus Fascia Plasty Flap for Pilonidal Sinus
Status: RECRUITING
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Primary Closure|PROCEDURE: Gluteus Maximus Fascia Plasty Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation
Status: TERMINATED
Conditions: Efficacy and Safety of Xenon Inhalation|Successful Cardiopulmonary Resuscitation|Addition to Therapeutical Hypothermia
Interventions: PROCEDURE: therapeutical hypothermia|DRUG: Xenon Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Alectinib|DRUG: Posaconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RevErsing Poor GrAft Function With eLtrombopag After allogeneIc Hematopoietic Cell trAnsplantation
Status: UNKNOWN
Conditions: Leukemia|Graft Failure
Interventions: DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief System
Status: TERMINATED
Conditions: Rib Fractures
Interventions: DEVICE: ON-Q bupivicaine administration|DRUG: IV opioid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anticoagulant Therapy in Portal Vein Thrombosis
Status: COMPLETED
Conditions: Liver Cirrhosis|Portal Vein Thrombosis
Interventions: DRUG: Nadroparin calcium, warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Tumor Hypoxia in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: High Intensity Interval Training bout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pr-conceptional Progesterone for Unexplained Recurrent Miscarriage
Status: COMPLETED
Conditions: Abortion, Habitual
Interventions: DRUG: Progesterone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction and Maintenance of Castration After Subcutaneous Injections of Triptorelin Pamoate in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin Pamoate 11.25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Monoclonal Antibody ch14.18/CHO Continuous Infusion in Patients With Primary Refractory or Relapsed Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: dinutuximab beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVER
Status: COMPLETED
Conditions: Metastatic or Incurable Non-small Cell Lung Cancer|Relapsed, Refractory Melanoma
Interventions: DRUG: omaveloxolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Maqui Berry Extract in Treating Oral Candidiasis in Diabetes Mellitus Patients and Systemically Healthy Persons
Status: RECRUITING
Conditions: Oral Candidiases
Interventions: DRUG: Miconazole|DIETARY_SUPPLEMENT: CandBerrol® lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Dexmedetomidine Versus Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging
Status: UNKNOWN
Conditions: MRI|Pediatric Sedation|Midazolam|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cyclic Variations in Altitude Conditioning (CVAC) on Wellness and Activity Measures
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: CVAC Device (Cyclic Variations in Altitude Conditioning)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Digitized Assessment for the Survival of Mature Anterior Teeth With Periapical Lesion After One Step Regenerative Approach Using Different Asepsis Maneuvers
Status: COMPLETED
Conditions: Dental Pulp Necrosis|Dental Pulp Disease|Dental Pulp; Degeneration
Interventions: PROCEDURE: Disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Robotic, Laparoscopic and Open Surgery for Enucleation of Benign Pancreatic Neoplasms
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumors
Interventions: PROCEDURE: Robotic surgery|PROCEDURE: Laparoscopic surgery|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Volume After Ingestion of Carbohydrate Drink vs Water in Obese Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Gastric Emptying
Interventions: PROCEDURE: Preopertive drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Cbt for Psychosis and Affect on Psychosis Symptoms
Status: COMPLETED
Conditions: Psychosis
Interventions: BEHAVIORAL: cognitive behaviour therapy|DRUG: Espidone|DRUG: Olepra|DRUG: Donu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Monalizumab|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metastatic Colorectal Cancer (RAS-wildtype) After Response to First-line Treatment With FOLFIR Plus Cetuximab
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Folinic Acid|DRUG: 5-FU|DRUG: 5-FU|DRUG: Cetuximab|DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: regorafenib|DRUG: Irinotecan 125mg|DRUG: Cetuximab wkly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy, Safety and PK/PD Profiles of Anticoagulation of HSK36273 for Injection in Continuous Renal Replacement Therapy Subjects
Status: NOT_YET_RECRUITING
Conditions: Renal Replacement Therapy
Interventions: DRUG: HSK36273|DRUG: Heparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of EYP001a in Patients With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Vonafexor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of U16 in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Relapsed or Refractory Non-Hodgkin's Lymphoma
Interventions: DRUG: U16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NOV03 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Mojave Study)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: NOV03|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pH
Status: UNKNOWN
Conditions: Bacterial Vaginosis
Interventions: DRUG: Lactobacillus Species|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Intervention Based on the Model of Occupational Harmony in Patients With CRSWD
Status: NOT_YET_RECRUITING
Conditions: Circadian Rhythm Sleep-Wake Disorder
Interventions: BEHAVIORAL: Occupational Therapy|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasogastric/Orogastric Tube Placement Verification Study Using RightSpot pH Indicator to Verify Gastric Acidity
Status: UNKNOWN
Conditions: Small Bowel Obstruction|Gastrointestinal Hemorrhage
Interventions: DEVICE: RightSpot pH Indicator|RADIATION: Chest radiograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG
Status: NOT_YET_RECRUITING
Conditions: Cardiac Disease|Surgery-Complications|Graft Failure
Interventions: PROCEDURE: Coronary artery bypass graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodiafiltration With Endogenous Reinfusion on Uremic Toxins Clearance of Maintenance Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: To Evaluate the Clearance Rate of Uremic Toxin by HFR
Interventions: OTHER: HFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin phosphate (+) metformin hydrochloride|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tight Glycemic Control Increases Cardiac Stem Cells During Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Oxidative Stress|Glycemic Control
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SPR741|DRUG: Ceftazidime|DRUG: Piperacillin/tazobactam|DRUG: Aztreonam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Morphine Sulfate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Functional Recovery Between Mobile Bearing Unicompartmental Knee Arthroplasty and Total Knee Arthroplasty
Status: COMPLETED
Conditions: Patient Reported Outcome Measure
Interventions: DEVICE: Oxford UKA|DEVICE: Vanguard TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes After Unified Versus Standard GDM Diagnosis
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Diagnosis|Pregnancy
Interventions: DIAGNOSTIC_TEST: NPRP criteria|DIAGNOSTIC_TEST: IADPSG criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Idelalisib in Combination With Rituximab for Previously Untreated Follicular Lymphoma and Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma|Small Lymphocytic Lymphoma
Interventions: DRUG: Idelalisib|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unsupervised Therapy After Stroke in the Home Setting With a Hand Rehabilitation Device (ReHandyBot)
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Supervised and minimally-supervised therapy with ReHandyBot|DEVICE: Unsupervised therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses
Status: UNKNOWN
Conditions: Refractive Errors|Astigmatism
Interventions: DEVICE: SynergEyes A2 Hybrid Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lens Fit and Lens Power of a New Contact Lens to Two Marketed Contact Lenses in a Population of Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: galy A Plus|DEVICE: seno A|DEVICE: galy A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Periodontal Parameters in Self-ligating Brackets Alone or With Corticotomy vs Conventional Brackets
Status: COMPLETED
Conditions: Crowding of Anterior Maxillary Teeth
Interventions: DEVICE: Conventional brackets|DEVICE: Self-ligating brackets|PROCEDURE: Self-Ligating Brackets with flapless corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above
Status: RECRUITING
Conditions: COVID-19 Pneumonia|Coronavirus Infections
Interventions: BIOLOGICAL: Recombinant COVID-19 Vaccine (CHO cell，NVSI-06-08)|BIOLOGICAL: Inactivated COVID-19 vaccine (Vero cells)|BIOLOGICAL: 3 doses Recombinant COVID-19 Vaccine (CHO cell，NVSI-06-08)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study.
Status: UNKNOWN
Conditions: Hepatic Encephalopathy.
Interventions: DRUG: Sildenafil.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells in Patients After Stroke
Status: WITHDRAWN
Conditions: Stroke
Interventions: PROCEDURE: Harvesting and Isolation of Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin A for BPD Prevention
Status: UNKNOWN
Conditions: The Relationship Between Oral Vitamin A Administration and the Incidence of BPD in Preterm Infants Born Before Week 29 of Pregnancy
Interventions: DIETARY_SUPPLEMENT: Oral Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Smart Catheter: A Novel Biosensor for Early Detection of Catheter Associated Urinary Tract Infection
Status: COMPLETED
Conditions: Catheter-Associated Urinary Tract Infection
Interventions: DIAGNOSTIC_TEST: Smart Catheter Biosensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Assessment of Impact of Personalized Dosing of Low-dose Human Chorionic Gonadotropin (hCG) on in Vitro Fertilization (IVF) Outcomes
Status: TERMINATED
Conditions: Infertility, Female
Interventions: OTHER: Low dose hCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (POAG)
Status: COMPLETED
Conditions: Eye Diseases|Glaucoma, Open-Angle|Glaucoma
Interventions: DEVICE: iStent|DRUG: latanoprost/timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
Status: COMPLETED
Conditions: Duodenal Diseases|White Spot Lesion
Interventions: DIAGNOSTIC_TEST: sws grade 1|DIAGNOSTIC_TEST: sws grade 2|DIAGNOSTIC_TEST: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury|Moderate Traumatic Brain Injury|Mild Cognitive Impairment
Interventions: DEVICE: No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan.|PROCEDURE: No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection Surgery
Status: COMPLETED
Conditions: Ileus
Interventions: DRUG: stool softener|DEVICE: Arm B: Acupressure bracelet|DIETARY_SUPPLEMENT: sugar free gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequencing CBT for Child Anxiety: CBT Plus Sertraline Versus Switch to Sertraline
Status: TERMINATED
Conditions: Anxiety Disorder of Adolescence
Interventions: DRUG: Sertraline|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation and Expansion Study of PXS-5505 in Patients With Primary, Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: PXS-5505
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer (NeoART-V)
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: artesunate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib, Irinotecan and S-1 (ApaIRIS) in Treating Patients With Metastatic Pancreatic Cancer After AG Regimen
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Apatinib|DRUG: S-1 capsule|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNAIR Inactivated COVID-19 Vaccine
Status: RECRUITING
Conditions: COVID-19 Pandemic|Vaccine Reaction
Interventions: BIOLOGICAL: UNAIR Inactivated COVID-19 Vaccine|BIOLOGICAL: CoronaVac Biofarma COVID-19 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs
Status: COMPLETED
Conditions: Gingivitis
Interventions: DIETARY_SUPPLEMENT: Oligomeric Proanthocyanidins|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CardioSenseSystem Compared Study Regarding Efficacy and Safety in the Monitoring of ECG
Status: UNKNOWN
Conditions: Cardiac Arrythmias|Unstable Angina|Heart Valve Disorders|Disorder of Aorta
Interventions: DEVICE: CardioSenseSystem|DEVICE: Philips Intellivue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Game on Philly: Engaging Underserved Middle School Youth in Out-of- School Time Sports and Nutrition Education
Status: COMPLETED
Conditions: Exercise|Diet
Interventions: BEHAVIORAL: Game on Philly: Engaging Underserved Middle School Youth in Out-of- School Time Sports and Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Interindividual Postexercise Hypotension Response in Morbid Obesity
Status: COMPLETED
Conditions: Metabolic Syndrome|Morbid Obesity
Interventions: BEHAVIORAL: Concurrent training order 1|BEHAVIORAL: RT+ET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: De Novo Lipogenesis, Lipid and Carbohydrate Metabolism in Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Diabetes
Interventions: OTHER: Dietary intervention (calorie restricted diet)|OTHER: Dietary intervention (calorie restricted diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Safety and Efficacy of Multiple-dose of WJ01024 in Subject With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Hematologic Malignancies|Advanced Solid Tumors
Interventions: DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024|DRUG: WJ01024
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children"
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Cefixime|DRUG: Cephalexin|OTHER: Placebo|DRUG: Trimethoprim/Sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial Craniotomy
Status: COMPLETED
Conditions: Opioid-Free Anaesthesia
Interventions: DRUG: Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Negative-Pressure Wound Therapy
Status: COMPLETED
Conditions: Pressure Ulcers Stage III|Pressure Ulcer, Stage IV
Interventions: DEVICE: Negative-Pressure Wound Therapy group|OTHER: contol group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Pediatric-type of chemotherapy|PROCEDURE: allogeneic HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Awareness for Spatial Neglect With tDCS
Status: UNKNOWN
Conditions: Stroke|Anosognosia|Neglect, Hemispatial
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized 129Xe Magnetic Resonance Imaging for Evaluation of Radiation-Induced Lung Injury in Subjects Undergoing Thoracic Irradiation
Status: TERMINATED
Conditions: Radiation Induced Lung Injury (RILI)
Interventions: DIAGNOSTIC_TEST: Hyperpolarized gas and proton lung MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of End-effector Type Robot Assisted Gait Therapy on Gait Pattern and Energy Consumption in Chronic Post-stroke Hemiplegic Patients
Status: COMPLETED
Conditions: Chronic Post-stroke Hemiplegic Patients
Interventions: DEVICE: Robot Assisted Gait Therapy|DEVICE: Conventional Gait Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Evaluate Safety and Efficacy of LME636 in the Treatment of Acute Anterior Uveitis
Status: COMPLETED
Conditions: Acute Anterior Uveitis
Interventions: DRUG: LME636 60 mg/mL ophthalmic solution|DRUG: Dexamethasone 0.1% ophthalmic solution|DRUG: LME636 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2a Study of CDK-003 in Patients With Cutaneous T-Cell Lymphoma (CTCL).
Status: TERMINATED
Conditions: Cutaneous T-cell Lymphoma (CTCL)
Interventions: BIOLOGICAL: CDK-003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Meditation on Cognitive Function and Quality of Life
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Questionnaires|PROCEDURE: Electroencephalography (EEG)|PROCEDURE: Magnetic Resonance Imaging (fMRI|BEHAVIORAL: Meditation Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Adding Dexmedetomidine Perineurally to Bupivacaine in Ultrasound Guided Fascia Iliaca Block Versus Intravenously Infused Dexmedetomidine on Hemodynamic Stability Intraoperatively and Postoperative Analgesia Following Hip Arthroscopy
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Bupivacaine hydrochloride perineurally|DRUG: Dexmedetmidine infusion|DRUG: Dexmedetomidine perineurally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Weaning Failure|Complication of Respirator [Ventilator]
Interventions: OTHER: Multidisciplinary weaning-ventilator protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Immunogenicity of Meningococcal Conjugate Vaccine in Healthy Adults Aged 19 to 55 Years Old
Status: COMPLETED
Conditions: Infection, Meningococcal
Interventions: BIOLOGICAL: Meningococcal(Groups A, C, W-135, and Y) Conjugate Vaccine|BIOLOGICAL: Meningococcal(Groups A, C, Y, and W-135) Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stem Cell Transplantation in Individuals With Multiple Myeloma (BMT CTN 0102)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: One Autologous Transplant|PROCEDURE: Non-Myeloablative Allogeneic Transplant|PROCEDURE: Second Autologous Transplant|DRUG: Thalidomide|DRUG: Dexamethasone|BEHAVIORAL: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT