pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Bifonazole cream 1%|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Q301 in Mild to Moderate Adolescents and Adults Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Q301 Cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Diabetes Relapse After Bariatric Surgery
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass|PROCEDURE: Laparoscopic adjustable gastric banding|PROCEDURE: Vertical Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib and Docetaxel in Patients With Prostate Cancer That Did Not Respond to Previous Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Passive Leg Elevation on the Cross-sectional Area of the Internal Jugular Vein in Infants or Young Children Undergoing Open Heart Surgery
Status: COMPLETED
Conditions: Infants or Children Undergoing Open Heart Surgery
Interventions: OTHER: leg elevation|OTHER: Trendelenburg position|OTHER: Trendelenburg position + passive leg elevation|OTHER: control group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Meditation Based Lifestyle Modification in Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Meditation Based Lifestyle Modification|OTHER: Minimal treatment|OTHER: Multimodal specific treatment:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Albuterol Spiromax® in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo MDPI|DRUG: Albuterol MDPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecystectomy Blunt Dissection
Status: ENROLLING_BY_INVITATION
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: dissection of gallbladder in laparoscopic cholecystectomy|PROCEDURE: dissection of gallbladder in laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Blood Safety and HIV Testing in Brazil
Status: COMPLETED
Conditions: HIV|Herpes Simplex 2|Hepatitis C|Hepatitis B|Chagas Disease
Interventions: BEHAVIORAL: HIV Counseling and Testing|BEHAVIORAL: Blood Donation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electrical Cardiometry Compared to Transthoracic Echocardiography in Fluid Responsiveness in Sepsis
Status: COMPLETED
Conditions: Electrical Cardiometry|Transthoracic Echocardiography|Fluid Responsiveness|Sepsis|Stoke Volume
Interventions: DEVICE: Electrical Cardiometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flashed Light Therapy for Adolescents With ADHD and Delayed Sleep Timing
Status: RECRUITING
Conditions: ADHD
Interventions: DEVICE: Flashed Light Therapy|BEHAVIORAL: Videoconference-delivered Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis
Status: UNKNOWN
Conditions: Psychotic Disorders|Schizophrenia|Schizoaffective Disorder|Delusional Disorder|Schizophreniform Disorder
Interventions: BEHAVIORAL: modified cognitive behavioural therapy (mCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effectiveness and Safety of DPCP Ointment (Samcyprone™) on the Clearance of Verruca Vulgaris (Common Warts)
Status: UNKNOWN
Conditions: Common Warts|HPV (Human Papillomavirus)|Periungual Warts|Plantar Warts
Interventions: DRUG: Sensitizing DPCP Ointment|DRUG: Treatment DPCP Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Brief Substance Misuse Preventative Intervention for Parents/Guardians of 5th-7th Grade Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance-Related Disorders|Underage Drinking|Drug Use
Interventions: BEHAVIORAL: The SUPPER Project|BEHAVIORAL: Improving nutrition and physical activity among youth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration, Age-Related
Interventions: OTHER: blood and aqueous humor sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: EVEREST II Pivotal Study High Risk Registry (HRR)
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Mitral Valve Regurgitation|Mitral Valve Incompetence|Mitral Regurgitation|Mitral Insufficiency
Interventions: DEVICE: Percutaneous mitral valve repair using MitraClip implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Medicine in Pain Management in Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Pain|Acupuncture|Quantitative Sensory Testing|Magnetic Resonance Imaging|Circulating Biomarkers|Electroencephalography|Functional Near-infrared Spectroscopy
Interventions: DEVICE: needling acupuncture|DEVICE: laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Head-and-neck Squamous-cell Carcinoma
Interventions: DRUG: nab-paclitaxel|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound-Guided Intraoperative Fluid Management Strategies
Status: NOT_YET_RECRUITING
Conditions: Shoulder Arthropathy Associated With Other Conditions
Interventions: OTHER: Intraoperative fluid management stratigies.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Effect Of Cross Titration Of Antipsychotics With Ziprasidone In Schizophrenia Or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Adolescent Females to Explore Cytomegalovirus Infection
Status: COMPLETED
Conditions: Infections, Cytomegalovirus
Interventions: PROCEDURE: Blood collection|PROCEDURE: Urine collection|PROCEDURE: Saliva collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Single-portal Endoscopic Carpal Tunnel Release Versus Knifelight for Carpal Tunnel Syndrome. A Randomized Control Trial
Status: WITHDRAWN
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Single-portal Endoscopic Carpal Tunnel Release (Microaire®)|PROCEDURE: Knifelight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Luteinizing hormone-releasing hormone (LHRH)|DRUG: Docetaxel|OTHER: Conformal Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Thromboelastography (TEG) in Patient's Requiring Extracorporeal Membrane Oxygenation (ECMO)
Status: COMPLETED
Conditions: Heart Disease|Lung Disease
Interventions: DEVICE: Thromboelastograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of a Simulation-based Training Curriculum of Non-technical Skills on Colonoscopy Performance
Status: COMPLETED
Conditions: Endoscopy Simulation
Interventions: OTHER: Non-Technical Skills Training Curriculum|OTHER: Conventional Simulation Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Obesity|Arthritis
Interventions: DRUG: propofol|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone for Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Vascular REactivity and Muscular Oxygenation in Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus|Vascular Complications|Mitochondrial Diseases
Interventions: OTHER: examination: blood pressure assessment|OTHER: examination: Flow Mediated Dilatation (FMD)-test|OTHER: examination: handgrip exercise test with Near infrared spectroscopy (NIRS)-monitoring|OTHER: examination: measurement of glucose by a finger prick
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Predictive Value of Spirometric PIF to Produce PIF Rate Needed for the Use of Current DPI's.
Status: UNKNOWN
Conditions: Severe Asthma|COPD
Interventions: DEVICE: In-check Dial device (Clement Clarke International Ltd, Harlow, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Trial of Defactinib and VS-6766.
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC|Low Grade Serous Ovarian Cancer|Endometrioid Carcinoma|Pancreatic Cancer
Interventions: DRUG: VS-6766|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ZnO Nanoparticles Coated Orthodontic Molar Tube
Status: COMPLETED
Conditions: Evaluations, Diagnostic Self|Antimicrobial|Orthodontic Appliance Complication|Bacterial Overgrowth|Dental White Spot|Plaque Induced Gingivitis|Plaque, Dental
Interventions: DEVICE: Zinc oxide nanoparticle coated orthodontic molar tubes (experimental)|DEVICE: orthodontic molar tubes (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychophysiological Effects of Probiotic Supplementation
Status: COMPLETED
Conditions: Mild to Moderate Levels of Stress
Interventions: DIETARY_SUPPLEMENT: Experimental probiotic product|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of S-1 Plus DC-CIK for Patients With Unresectable Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: DC-CIK Treatment|DRUG: S1|OTHER: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Molecular Residual Disease Monitoring Based on ctDNA in Advanced or Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Later-line therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-dependent Effect of Fentanyl on Cough Attenuation During Emergence From General Anaesthesia
Status: COMPLETED
Conditions: Thyroid Neoplasm
Interventions: DRUG: fentanyl citrate|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Investigate Relative Bioavailability of up to Five Different Formulations of AZD5069
Status: COMPLETED
Conditions: Uncontrolled and Persistent Asthma
Interventions: DRUG: Phase IIb formulation|DRUG: Putative phase III formulation|DRUG: Slow dissolution variant 1|DRUG: Slow dissolution variant 2|DRUG: Test treatment E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial of Two Surgical Techniques for Pancreaticojejunostomy in Patients Undergoing Pancreaticoduodenectomy
Status: TERMINATED
Conditions: Pancreatic Neoplasms|Biliary Tract Neoplasms|Pancreatitis, Chronic|Duodenal Neoplasms
Interventions: PROCEDURE: pancreaticojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Combined Ergonomic Health Promotion Intervention on Employee Health
Status: COMPLETED
Conditions: Sedentary|Overweight
Interventions: BEHAVIORAL: Active Workstation Intervention|BEHAVIORAL: Ergonomic Intervention|BEHAVIORAL: Email Intervention|DEVICE: Bluetooth enabled device (Wahoo Fitness Blue SC sensor) and accompanying iPod application.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the NHIPEC Trial)
Status: RECRUITING
Conditions: Hyperthermic Intraperitoneal Chemotherapy|Neoadjuvant Chemotherapy
Interventions: PROCEDURE: HIPEC|PROCEDURE: intravenous chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF RISPERIDONE vs ARIPIPRAZOLE ON OXIDATIVE STRESS IN PATIENTS WITH AUTISM SPECTRUM DISORDER: A RANDOMIZED CONTROLLED TRIAL
Status: NOT_YET_RECRUITING
Conditions: The Goal of This Trial is to to Compare the Effect of Risperidone vs Aripiprazole in Terms of Change in Serum Glutathione Level
Interventions: DRUG: Risperidone, Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
Status: RECRUITING
Conditions: Developmental Dysplasia of the Hip
Interventions: DIAGNOSTIC_TEST: Intraoperative contrast-enhanced ultrasound (CEUS)|DRUG: Lumason
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Pulsed-field Ablation for Atrial Fibrillation in High Versus Low-volume Ablation Centers (SAFFICIENT)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Catheter ablation using pulsed-field ablation (PFA) system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions
Status: RECRUITING
Conditions: Multiple Chronic Conditions|Decision Making, Shared
Interventions: BEHAVIORAL: Patient Priorities Care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Predictive Factors for Prescribing a Mandibular Advancement Device for the Treatment of Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: RADIATION: Pharyngeal Computed Tomography|DRUG: Drug-Induced Sleep Endoscopy (Propofol)|DEVICE: Mandibular Advancement Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing The Effects of Exercise, Protein, and Electric Stimulation On Intensive Care Unit Patients Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscle Weakness|Critical Illness|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: ER+ HER2- Advanced Breast Cancer|High-grade Serous Ovarian Cancer (HGSOC)
Interventions: DRUG: AZD8421|DRUG: Camizestrant|DRUG: Ribociclib|DRUG: Palbociclib|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Measurement: Should Technique Define Targets?
Status: COMPLETED
Conditions: Hypertension
Interventions: DIAGNOSTIC_TEST: BpTRU First, Unattended Omron Second|DIAGNOSTIC_TEST: Unattended Omron First, BpTRU Second|DIAGNOSTIC_TEST: Partially Attended Omron First, Unattended Omron Second
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Zemplar® Injection and Hectorol® Injection on Intestinal Absorption of Calcium in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease, Stage 5|Secondary Hyperparathyroidism
Interventions: DRUG: Zemplar® injection|DRUG: Hectorol® injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumors
Interventions: RADIATION: Radiotherapy without Carboplatin|DRUG: Reduced-intensity maintenance chemotherapy|RADIATION: Radiotherapy with Carboplatin|DRUG: Maintenance chemotherapy|RADIATION: WNT-HR < 16 years|RADIATION: WNT-HR >= 16 years|DRUG: Induction Chemotherapy|RADIATION: SHH-TP53 M0|RADIATION: SHH-TP53 M+ (germline)|RADIATION: SHH-TP53 (somatic)|DRUG: Vinblastin Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety and Immunogenicity of PNEUMOSIL® Vaccine in Healthy Vietnamese Children, 6 Weeks to 24 Months of Age
Status: UNKNOWN
Conditions: Streptococcus Pneumonia|Vaccine Preventable Disease
Interventions: BIOLOGICAL: PNEUMOSIL®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotic Supplementation on Immune Function in Healthy Infants
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Covid-19 Predictors: Safety of Gynecological Oncology Patients Undergoing Systemic Cancer Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Telemedicine
Interventions: DEVICE: PPG and PROM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Total Knee Arthroplasty --- A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Postoperative Pain|Total Knee Arthroplasty
Interventions: PROCEDURE: CFNB group|PROCEDURE: LWI group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Artery Embolization as a Treatment for Benign Prostatic Hyperplasia in Men With Prostates Larger Than 90 Grams
Status: TERMINATED
Conditions: Prostatic Hyperplasia
Interventions: DEVICE: Embosphere Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frozen-thawed Embryo Transfer in a Natural Cycle: hCG Triggering Versus LH Home Test
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Human chorionic gonadotropin|OTHER: Home ovulation test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity AlloTransplant For Osteopetrosis
Status: TERMINATED
Conditions: Osteopetrosis
Interventions: PROCEDURE: Stem Cell or Umbilical Cord Blood Transplantation|DRUG: Campath, Busulfan, Clofarabine|PROCEDURE: Total Lymphoid Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0010 506U78 in Treating Patients With Recurrent or Refractory Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Autonomic Dysfunction
Interventions: DEVICE: TESCoN device - Thoracic stimulation|DEVICE: TESCoN device - Lumbosacral stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Local Anaesthetic in Bowel Surgery
Status: COMPLETED
Conditions: Colorectal Disorders
Interventions: DRUG: Ropivacaine|DRUG: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: BGB-C354|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Enteral Glutamine Supplementation in Patients With Predicted Severe Acute Pancreatitis- A Double-Blinded Randomized Controlled Trial
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DIETARY_SUPPLEMENT: Enteral glutamine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
Status: RECRUITING
Conditions: Degenerative Disc Disease|Back Pain Lower Back Chronic|Facet Joint Arthropathy|Facet Syndrome of Lumbar Spine
Interventions: PROCEDURE: Lumbar fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effects of an Hypertonic Solution With Ringer Lactate on Right Ventricular Function Following Cardiac Surgery
Status: COMPLETED
Conditions: Right Ventricular Impaired Function|Hypovolemia
Interventions: DRUG: Ringer Lactate (10ml/kg) fluid expansion|DRUG: Hypertonic saline (3ml/kg) fluid expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury|Cognitive Symptoms
Interventions: BEHAVIORAL: Cognitive Intervention|BEHAVIORAL: Educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-PRF in Cranial Surgery
Status: UNKNOWN
Conditions: Cranial Sutures; Closure
Interventions: PROCEDURE: Dural closure with L-PRF|PROCEDURE: Dural closure with classical fibrin sealants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Time-restricted Eating Among Pregnant Females With Severe Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid|Time Restricted Eating|Pregnancy Weight Gain
Interventions: BEHAVIORAL: Time Restricted Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone Versus Methylprednisolone for the Treatment of Active Inflammatory Bowel Disease
Status: TERMINATED
Conditions: Inflammatory Bowel Disease (IBD)
Interventions: DRUG: Dexamethasone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Granulomatous Disease Transplant
Interventions: DRUG: Alemtuzumab|DRUG: Busulfan|DRUG: Sirolimus|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation|BIOLOGICAL: Peripheral blood stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter, PhaseⅣ, Open Label Trial of Nilotinib in Adult Patients Diagnosed Philadelphia Chromosome Positive(Ph+) Chronic Myeloid Leukemia in CP/AP Intolerant to Dasatinib
Status: UNKNOWN
Conditions: Leukemia, Chronic Myeloid
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intratympanic Application of Dexamethasone Via Catheter in Patients With Sudden Hearing Loss
Status: COMPLETED
Conditions: Sudden Deafness
Interventions: DRUG: Dexamethasone-dihydrogenphosphate (4mg/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Ruxian Zengsheng No. 1 Decoction
Status: UNKNOWN
Conditions: Mammary Gland Hyperplasia
Interventions: DRUG: Rugdenzengsheng No. 1 prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy
Status: RECRUITING
Conditions: ERAS|Surgery|Appendicitis
Interventions: OTHER: Education and counselling|OTHER: Avoiding the use of nasogastric catheters, drains and urinary catheters|OTHER: Stimulation of intestinal motility in the postoperative period|OTHER: Initiation of oral intake in the early postoperative period|OTHER: Early removal of the patient by reducing postoperative IV fluid infusion|OTHER: Initiation of early mobilization of the patient in the postoperative period|OTHER: Reducing opioid use and ensuring pain management|OTHER: Implement nausea and vomiting prophylaxis|OTHER: Management of thirsty|OTHER: Management of fear and stress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK, PD, Tolerability and Safety of MDPK67b in Healthy Volunteers
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: MDPK67b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides
Status: TERMINATED
Conditions: Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Interventions: DRUG: Cobomarsen|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Radial Artery Occlusion in Coronary Diagnosis and Intervention Via Distal Radial Approach (CONDITION)
Status: COMPLETED
Conditions: Coronary Artery Disease|Distal Radial Artery|Radial Artery Occlusion
Interventions: PROCEDURE: distal radial approach|PROCEDURE: conventional radial access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimising the Propranolol Block Model
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Propranolol|DRUG: Salbutamol|DRUG: Ipratropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiple Ascending Dose Study of Miravirsen in Treatment-Naïve Chronic Hepatitis C Subjects
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: miravirsen|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Urine Bag Usage Versus Chest Drain Clamping After Lung Resection Surgeries
Status: UNKNOWN
Conditions: Pneumothorax and Air Leak|Pneumothorax|Pleura Injury|Pleural Effusion
Interventions: OTHER: Clamping|OTHER: Urine bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency
Status: NOT_YET_RECRUITING
Conditions: Primary Adrenal Insufficiency|Intermittent Fasting
Interventions: BEHAVIORAL: intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Fluviral® (2012/2013 Season) in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluviral®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Food Effect Study on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Interventions: DRUG: VC004 Capsules|DRUG: VC004 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Intracoronary Injection of Autologous BMMC for LV Contractility and Remodeling in Patients With STEMI
Status: UNKNOWN
Conditions: Heart Failure|Myocardial Infarction
Interventions: PROCEDURE: Intracoronary infusion of BM-MC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy for Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: BIOLOGICAL: Oncoquest-CLL vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb
Status: COMPLETED
Conditions: Dupuytren's Contracture
Interventions: BIOLOGICAL: Injectable clostridial collagenase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Using Portable Electronic Recorders for Sleep Apnea in Hypertensive At-Risk Populations (SUPER-SHARP Trial)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Hypertension
Interventions: DEVICE: Home Sleep Apnea Test|DEVICE: In-laboratory polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Lipikar Urea 30% Before Actinic Keratoses Treatment
Status: RECRUITING
Conditions: Actinic Keratoses
Interventions: OTHER: Group A: holistic approach|OTHER: Group B: Tolak® Standard of use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Providing Suboxone and PrEP Using Telemedicine
Status: COMPLETED
Conditions: Opioid Use|Opioid-use Disorder|Risk Reduction|Hiv
Interventions: DRUG: Suboxone|DRUG: PrEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: 131I-F16SIP Radioimmunotherapy (RIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Behavioral Treatments for Obesity and Major Depression in Women
Status: COMPLETED
Conditions: Depression|Obesity
Interventions: BEHAVIORAL: Weight loss treatment|BEHAVIORAL: Behavior therapy for depression|BEHAVIORAL: Health education counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: cisplatin|DRUG: raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Clinical Application of Tauroursodeoxycholic Acid in Patients With Liver Fibrosis.
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DRUG: Tauroursodeoxycholic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinic to Community© Program for Adults With Epilepsy Admitted to Emergency Departments
Status: COMPLETED
Conditions: Epilepsy, Generalized
Interventions: BEHAVIORAL: Clinic to Community Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: multifocal intraocular lens implantation|PROCEDURE: monofocal intraocular lens implantation|DRUG: Dexamethasone|DEVICE: multifocal intraocular lens (IOL) (Tecnis ZMB00)|DEVICE: monofocal intraocular lens (IOL) (Tecnis ZCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Provider Intervention to Address Intersectional Stigma and Medical Mistrust
Status: ACTIVE_NOT_RECRUITING
Conditions: Stigma, Social
Interventions: BEHAVIORAL: Provider Intervention on Addressing Intersectional Stigma and Medical Mistrust in Patients with HIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HD16 for Early Stage Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Hodgkin Lymphoma
Interventions: DRUG: ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine)|RADIATION: 20 Gy IFRT (Involved Field Radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Deprivation Therapy, External Beam Radiotherapy and Stereotactic Radiosurgery Boost for Prostate Cancer
Status: COMPLETED
Conditions: Neoplasm, Prostate
Interventions: RADIATION: Cyberknife boost 18 Gy|RADIATION: Cyberknife boost 21 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Sham Controlled Trial of rTMS in Treatment Resistant Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: TMS|DEVICE: Sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin Plus Ezetimibe on Coronary Plaque Progression
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: atorvastatin|DRUG: atorvastatin plus ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebellar-spinal Transcranial Pulsed Current Stimulation (tPCS) for Treatment of Neurodegenerative Ataxia
Status: RECRUITING
Conditions: Cerebellar Ataxia
Interventions: DEVICE: Active Transcranial Pulse Current Stimulation|DEVICE: Sham Transcranial Pulse Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1210 in Combination With AIN457 in Patients With MSS CRC（SHR-1210-AIN457）
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: SHR-1210|DRUG: AIN 457
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual-mobility Cups Compared to Unipolar Cups on Dislocation and Cost-effectiveness After Primary Total Hip Arthroplasty.
Status: RECRUITING
Conditions: Total Hip Arthroplasty|Osteoarthritis, Hip
Interventions: PROCEDURE: Unipolar cup|PROCEDURE: Dual mobility cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Finding the Best Dose of Aspirin to Prevent Lynch Syndrome Cancers
Status: NOT_YET_RECRUITING
Conditions: Lynch Syndrome I (Site-specific Colonic Cancer)
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Autologous Mesenchymal Stem Cells Transplantation to Treat Middle Cerebral Artery Infarct
Status: UNKNOWN
Conditions: Middle Cerebral Artery Infarction
Interventions: OTHER: Standard medical care|BIOLOGICAL: Autologous bone marrow-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial
Status: RECRUITING
Conditions: Primary Brain Tumor|Glioblastoma|Astrocytoma|Oligodendroglioma|Meningioma|Primary Central Nervous System (CNS) Lymphoma
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning
Status: RECRUITING
Conditions: Sepsis|Septicemia|Respiratory Failure|Hemodynamic Instability|COVID-19|Cardiac Arrest|Clinical Deterioration
Interventions: DEVICE: eCARTv5 clinical deterioration monitoring|OTHER: Standard of care control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of NNZ-2566 in Patients With Traumatic Brain Injury Under EFIC
Status: COMPLETED
Conditions: Brain Injuries
Interventions: DRUG: NNZ-2566|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Variable-Resistance Training in Pediatric Survivors of Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: Adaptive variable-resistance training|OTHER: Standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Drug for Benign Prostatic Hyperplasia (BPH) Compared With Placebo
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Silodosin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy
Status: COMPLETED
Conditions: Spinal Tumor
Interventions: RADIATION: Spinal SBRT (Standard Dose)|RADIATION: Spinal SBRT (Higher Dose)|PROCEDURE: Gold Seed Implantation|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegasys Plus Entecavir Versus Entecavir Versus Pegasys for Hepatitis B e Antigen-Negative Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Pegasys&Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-bisabolol for Onychomycosis Treatment
Status: COMPLETED
Conditions: Onychomycosis
Interventions: BIOLOGICAL: Drug recommended by the Brazilian Society of Dermatology|COMBINATION_PRODUCT: Alpha bisabolol product and laser|BIOLOGICAL: Alpha bisabolol product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the 532 nm KTP Laser for the Treatment of Poikiloderma of Civatte
Status: COMPLETED
Conditions: Poikiloderma of Civatte|Dyschromia|Pigmentation Disorders|Telangiectasia|Photosensitivity Disorders
Interventions: DEVICE: 532 nm KTP laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Alpha Tocopherol for Prevention of Contrast-induced Nephropathy in Chronic Kidney Disease (CKD) Patients
Status: UNKNOWN
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: alpha tocopherol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function
Status: COMPLETED
Conditions: Thyroid Goiter|Thyroid Carcinoma|Multinodular Goiter|Graves Diseases
Interventions: PROCEDURE: Thyroidectomy and parathyroid reimplantation in forearm subcutaneous tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Status: COMPLETED
Conditions: Trichotillomania
Interventions: BEHAVIORAL: Device and app system designed for participant to self-administer Habit Reversal Training|BEHAVIORAL: Reminder bracelet control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Colorectal Cancer Screening Intervention Trial
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Cancer Screening
Interventions: OTHER: Control|OTHER: Reduced out of pocket expense|BEHAVIORAL: one on one education|BEHAVIORAL: Group education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of a PillCam Colon Bowel Preparation Regimen in Crohn's Disease Patients
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: OTHER: bowel prep regimen first boost 6 oz. and second boost 3 oz.|OTHER: bowel prep regimen first boost 3 oz. and second boost 6 oz.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER