pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Strawberries and Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: FDS-Strawberry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incorporation of a Health Equity Approach to Hospital Violence Intervention Programs: The Integration of a Community and Hospital Based Initiatives to Reduce Gun Violence in a Large Metropolitan Area
Status: NOT_YET_RECRUITING
Conditions: Firearm Injury
Interventions: BEHAVIORAL: Houston-HVIP treatment|BEHAVIORAL: Enhanced Case Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation
Status: COMPLETED
Conditions: QTc Evaluation|Electrocardiography
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trochanteric Hip Fractures (AO A2) SHS With or Without Trochanteric Stabilizing Plate - Rct Using RSA
Status: COMPLETED
Conditions: Hip Fractures|Trochanteric Fractures|Intertrochanteric Fractures
Interventions: DEVICE: Sliding Hip Screw with Trochanteric Stabilization Plate|DEVICE: Sliding Hip Screw without Trochanteric Stabilization Plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Spinal Manipulation for Headache
Status: RECRUITING
Conditions: Cervicogenic Headache|Tension-Type Headache
Interventions: OTHER: Spinal Manipulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Buparlisib and Ibrutinib in Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Mantle Cell Lymphoma|Follicular Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: Buparlisib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Trastuzumab Plus Standard Chemotherapy Given Before Surgery in Breast Cancer Patients With Low HER 2 Expression
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: nab-paclitaxel|DRUG: trastuzumab|DRUG: Doxorubicin|DRUG: cyclophosphamide|BIOLOGICAL: Growth Factor Support|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-97540, CD19-targeted NEX-T Chimeric Antigen Receptor (CAR) T Cells, in Subjects With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma Non-Hodgkin|Agressive Lymphoma|Diffuse-large B-cell Lymphoma (DLBCL)
Interventions: BIOLOGICAL: CC-97540
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Abraxane Weekly and Three Weekly Schedule With Vandetanib
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Weekly Abraxane and Daily Vandetanib|DRUG: Abraxane every three weeks and daily vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients
Status: RECRUITING
Conditions: Psychosis|Alcohol Use Disorder
Interventions: BEHAVIORAL: Cognitive Enhancement Therapy (CET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk-adapted Stereotactic Body Radiotherapy for Early Non-Small Cell Lung Cancer Using the VERO Stereotactic Body Radio Therapy System
Status: UNKNOWN
Conditions: Non-Small Cell Lung Carcinoma
Interventions: RADIATION: Radiotherapy (Fractionated stereotactic body radiation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study On The Performance And Safety Of The LEDINBIO CE Device On Visual Acuity In Subjects With Cataract
Status: RECRUITING
Conditions: Cataract in Old Age
Interventions: DEVICE: Treated with Ledinbio device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation of Multidomain Cognitive Impairment in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Clinical assessment|OTHER: Classical cognitive evaluation of several domains:|OTHER: Ecological evaluation|BEHAVIORAL: Patent reported outcomes (PRO's)|OTHER: Telerehabilitation : active procedure|OTHER: Telerehabilitation : comparator procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Gut Microbiome Restoration on Primary Hypertension Via Dietary Intervention
Status: RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Innovative Dietary Formulation (Patent ID: CN110250417A)|DRUG: Losartan 50mg per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus
Status: COMPLETED
Conditions: Barrett Esophagus|Esophageal Neoplasms|Reflux Esophagitis
Interventions: DEVICE: Endoscopy with Polyscope (Polydiagnost TM) coupled with Multi-Spectral Imaging light-source
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Sedation Monitoring Using Frontal Electroencephalogram, Electromyogram and Hemodynamic Responses to Pain in Critical Care
Status: COMPLETED
Conditions: Electroencephalography|Critical Care|Electromyography
Interventions: DIAGNOSTIC_TEST: Continuous EEG and EMG monitoring, with derived variables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PICU-related Sleep and Circadian Dysregulation Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Circadian Dysrhythmia|Sleep Disturbance|Critical Illness|Children, Only
Interventions: OTHER: Daytime light exposure|OTHER: Daytime restricted feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Bioequivalence of Estradiol Vaginal Inserts, 10 mcg and Vagifem® 10 mcg and Compare to Placebo
Status: COMPLETED
Conditions: Atrophic Vaginitis Due to Menopause
Interventions: DRUG: Estradiol Vaginal Tablets 10 mcg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prophylactic Acyclovir and Placebo in Prevention of Eczema Herpeticum in Pediatric Burns
Status: COMPLETED
Conditions: Herpes Virus Infection
Interventions: DRUG: Intravenous Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Eye Disease
Interventions: DRUG: AMA0076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maximizing Trichiasis Surgery Success
Status: COMPLETED
Conditions: Trichiasis|Surgery
Interventions: PROCEDURE: Bilamellar 3 mm|PROCEDURE: Bilamellar 5 mm|PROCEDURE: Trabut 3 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous And Pulsed Ultrasound Treatments On Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: ultrasound|DEVICE: pulsed ultrasound|DEVICE: placebo ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Control of Blood Pressure in Acute Ischemic Stroke After Endovascular Therapy on Clinical Outcome (CRISIS I)
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: OTHER: Intensive BP lowering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Immunogenicity Study in HAE Subjects Treated With Berinert
Status: COMPLETED
Conditions: Hereditary Angioedema Types I and II
Interventions: BIOLOGICAL: Berinert, lyophilizate for IV application containing 500 IU C1-INH to be reconstituted with 10 mL water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Prapela® SVS Incubator Pad for Apnea of Prematurity
Status: NOT_YET_RECRUITING
Conditions: Apnea of Prematurity
Interventions: DEVICE: SVS mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Plantago Ovata Husk on the Lipid Profile of Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Cardiovascular Disease
Interventions: DRUG: Plantago ovata husk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Visual Function Supplement Study
Status: COMPLETED
Conditions: Diabetes Mellitus - Type 1|Diabetes Mellitus - Type 2|Non-proliferative Diabetic Retinopathy
Interventions: DIETARY_SUPPLEMENT: multi-component nutritional supplement capsules|DIETARY_SUPPLEMENT: multi-component dietary supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega -3 Fatty Acid in Combination With Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: Eicosapentaenoic Acid|DRUG: Tyrosine kinase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ongoing Registry of Treatment of Chronic Venous Diseases
Status: RECRUITING
Conditions: Varicose Veins of Lower Limb
Interventions: PROCEDURE: conventional surgery|PROCEDURE: endovenous laser ablation|PROCEDURE: sclerotherapy|PROCEDURE: endovenous radiofrequency ablation|PROCEDURE: phlebectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (Cervarix) in Healthy Female Filipino Subjects Vaccinated According to the Prescribing Information From the Age of 10 Years Onwards.
Status: TERMINATED
Conditions: Human Papillomavirus Infection Leading to Cervical Cancer
Interventions: BIOLOGICAL: Cervarix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Benefit of a High Frequency Ventilation System During Lung or Breast Cancer Radiotherapy Treatment
Status: TERMINATED
Conditions: Lung Cancer|Breast Cancer
Interventions: DEVICE: High Frequency Percussive Ventilation|OTHER: Free breathing|OTHER: Active Breathing Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FREERIDE STUDY, Freeway Paclitaxel Coated Balloon Catheter to Treat Peripheral Artery Disease
Status: UNKNOWN
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Percutaneous transluminal angioplasty with uncoated balloon|DEVICE: Percutaneous transluminal angioplasty with Paclitaxel balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II RCT to Assess Efficacy of Intravenous Administration of Oxytocin in Patients Affected by COVID-19
Status: WITHDRAWN
Conditions: Covid-19|Corona Virus Infection|SARS-CoV 2
Interventions: DRUG: Oxytocin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure
Status: NOT_YET_RECRUITING
Conditions: Hypoxia|Gastric Polyp|Colon Cancer|Esophageal Cancer
Interventions: DEVICE: the COMBO Endoscopy Oropharyngeal Airway|DEVICE: Regular Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
Status: COMPLETED
Conditions: Neurofibromatosis Type 2|Vestibular Schwannomas
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor
Status: TERMINATED
Conditions: Cesarean Section|Surgical Site Infection|Nosocomial Infection
Interventions: DRUG: 2% chlorhexidine gluconate cloth|DRUG: 4% Chlorhexidine gluconate vaginal scrub
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy
Status: COMPLETED
Conditions: Wheezing|Allergy
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Open Label, Single Dose, 2-Way Cross-over Clinical Trial to Compare the Safety and Pharmacokinetic Characteristics of Exforge® and G-0081 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteer
Interventions: DRUG: Exforge®|DRUG: G-0081
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Added to Bupivacaine Versus Bupivacaine inTransincisionalU/S Guided Quadratus Lumborum Block in Open Renal Surgeries , A New Technique
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine +bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the TENA SmartCare Change Indicator on Care Efficiency and Skin Health in Long Term Care Facilities
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: TENA SmartCare Change Indicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prednisone for CRPS in Distal Radius Fracture
Status: NOT_YET_RECRUITING
Conditions: Complex Regional Pain Syndromes|Distal Radius Fractures
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Wearable Morning Light Treatment for Postpartum Depression
Status: RECRUITING
Conditions: Post Partum Depression
Interventions: DEVICE: Bright Light Therapy|DEVICE: Dim Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Salbutamol on Mannitol Induced Cough Responses in Healthy Controls
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Salbutamol 5mg/mL|DRUG: Sodium Chloride 0.9% Inhl 3Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorder|Posttraumatic Stress Disorder (PTSD)
Interventions: DRUG: Prazosin|DRUG: Naltrexone|DRUG: Placebo (Prazosin)|DRUG: Placebo (Naltrexone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Fentanyl Buccal Tablets Compared With Immediate-Release Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persona MC Retained PCL vs. Persona Posterior-stabilized vs. NexGen PS
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Knee Arthritis|Joint; Arthrosis, Primary
Interventions: PROCEDURE: Total knee replacement|DIAGNOSTIC_TEST: CT scan|DIAGNOSTIC_TEST: Biomechanics|DEVICE: one of the Persona MC Retained PCL, Persona MC Sacrificed PCL and NexGen PS total knee implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin and Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal Administration
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Hydromorphone Hydrochloride|DEVICE: Programmable Implantable pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head Acupuncture Treat Residual Symptoms After Canalith Repositioning Procedure for BPPV
Status: RECRUITING
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: PROCEDURE: Group A|DRUG: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound Guided Erector Spinae Plane Block Against Ultrasound Guided Serratus Anterior Block in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Breast Cancer|Postoperative Pain
Interventions: PROCEDURE: Serratus Anterior Plane Block|PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension
Status: WITHDRAWN
Conditions: Complications; Cesarean Section|Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cone-beam Computed Tomography (CBCT) Assistance to Video-assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Thoracoscopy
Interventions: PROCEDURE: CBCT acquisition|PROCEDURE: Anesthesia and surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: DRUG: enteral nutrition|DRUG: Tripterygium glycosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Braces for Treatment of Sever's Disease
Status: COMPLETED
Conditions: Sever's Disease
Interventions: DEVICE: Cheetah Heel Cup|DEVICE: The X Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted Approach to Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: PROCEDURE: Abdominal radical hysterectomy|PROCEDURE: Robot-assisted radical hysterectomy|DIAGNOSTIC_TEST: Sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability Trial of a Video Based CBT Guided Self Help Intervention for People With Low Literacy
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Video-based CBT guided self-help Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Plaque and Brain Inflammation in Symptomatic Carotid Stenosis: Role of the Ficolin-2
Status: NOT_YET_RECRUITING
Conditions: CAROTID STENOSIS
Interventions: DRUG: [18F]DPA-714 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hand Exoskeleton Controlled by BCI in Post Stroke Patients
Status: COMPLETED
Conditions: Poststroke/CVA Paresis
Interventions: DEVICE: hand exoskeleton, brain-computer interface (BCI),|DEVICE: hand exoskeleton, sham BCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phaco-UCP Versus Phaco Alone for OAG and Cataract
Status: COMPLETED
Conditions: Cataract|Glaucoma, Open-Angle
Interventions: PROCEDURE: combined phacoemulsification and ultrasound ciliary plasty (Phaco-UCP)|PROCEDURE: Phacoemulsification alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Develop and Implement Methods for Diagnostic and Treatment of Hormonal Disorders in Patients With Chronic Kidney Disease
Status: UNKNOWN
Conditions: Hyperprolactinemia|Thyroid Dysfunction|Bone Diseases, Metabolic|Chronic Kidney Diseases
Interventions: OTHER: Ultrasound, DXA, hormonal tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention or Treatment of Arterial Hypotension and Oxygen Cerebral Saturation During Major Abdominal Surgery
Status: COMPLETED
Conditions: Hypotension During Surgery|Hemodynamic Instability
Interventions: DEVICE: HPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer
Status: RECRUITING
Conditions: Differentiated Thyroid Carcinoma
Interventions: DRUG: ST-1898 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Zoledronic Acid Versus Alendronate on Bone Loss After Kidney and Kidney/Pancreas Transplants
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Zoledronic Acid|COMBINATION_PRODUCT: Calcium with vitamin D|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CLBS03 in Adolescents With Recent Onset Type 1 Diabetes (The Sanford Project T-Rex Study)
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: CLBS03 Low Dose|BIOLOGICAL: CLBS03 High Dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Brain Concussion|Pediatric|Mild Traumatic Brain Injury|Psychological
Interventions: BEHAVIORAL: Sub symptom aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of NN5401 With Insulin Glargine, Both in Combination With Oral Antidiabetic Drugs, in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Different Palatal Contour Designs on Patients' Satisfaction and Oral Health Related Quality of Life
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: OTHER: Polished palatal surface|OTHER: Roughened palatal surface|OTHER: Opened palatal surface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Routine Antibiotic vs. Directed Antibiotic Treatment in Snake Bite
Status: TERMINATED
Conditions: Snake Bites
Interventions: DRUG: Co-amoxiclav|BIOLOGICAL: Tetanus toxoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Adenocarcinoma|Prostatic Neoplasms|Prostatic Diseases|Neoplasms
Interventions: DIAGNOSTIC_TEST: bpMRI|DIAGNOSTIC_TEST: Image-Fusion targeted and systematic Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease
Status: RECRUITING
Conditions: Caregivers|Emotions|Emotion Regulation|Stress|Psychological|Psychophysiology
Interventions: BEHAVIORAL: Cognitive Emotion Regulation Training via Psychological Distancing|BEHAVIORAL: Cognitive Emotion Regulation Training via Reinterpretation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Dalotuzumab Alone and With Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-062 AM1)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: dalotuzumab|DRUG: dalotuzumab|DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom Management for YA Cancer Survivors
Status: COMPLETED
Conditions: Cancer|Young Adult|Pain|Psychological Distress|Fatigue|Breast Cancer|Melanoma|Hematologic Cancer|Germ Cell Tumor|Endocrine Cancer
Interventions: BEHAVIORAL: Behavioral Symptom Management for Young Adult Cancer Survivors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Nordic Phase II Study of PTCL Based on Dose-intensive Induction and High-dose Consolidation With ASCT
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: CHOEP + G-CSF followed by BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survive and Thrive Boa Vista Early Childhood Program
Status: UNKNOWN
Conditions: Neonatal Death|Mental Competency
Interventions: BEHAVIORAL: Home visits to improve parenting behaviors|BEHAVIORAL: Center based parenting groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Pulmonary Rehabilitation on Cognitive Status in Lung Transplantation Candidates
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Impairment|Pulmonary Rehabilitation
Interventions: OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Pomalidomide Monotherapy in Subjects With Refractory or Relapsed Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fermented Papaya Preparation on Patients With Chronic Kidney Disease Under Dialysis Receiving Intravenous Iron
Status: UNKNOWN
Conditions: Anemia|Chronic Kidney Disease Stage 5
Interventions: DIETARY_SUPPLEMENT: fermented papaya preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine and Midazolam Infusions for CRPS: Feasibility Study
Status: WITHDRAWN
Conditions: Complex Regional Pain Syndromes
Interventions: DRUG: Ketamine|DRUG: Midazolam|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIA FF/VI Study to Measure FeNO in Asthmatic Patients.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate (FF) (100 mcg)|DRUG: Vilanterol (VI) (25 mcg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: DePuy ASR™ Hip System|DEVICE: DePuy ASR™ XL Head / ASR™ Acetabular Cup System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PK and Safety of OXC (Oxcarbazepine) XR (Extended Release) as Adjunctive Therapy in Pediatric Epilepsy Patients
Status: COMPLETED
Conditions: Epilepsies, Partial
Interventions: DRUG: SPN-804O
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph1 to Assess Safety, Tolerability of Tremelimumab/ Tremelimumab+MEDI4736 in Japanese Solid Malignancies/ Mesothelioma
Status: COMPLETED
Conditions: Part A and B: Advanced Solid Malignancies|Part C: Malignant Mesothelioma
Interventions: DRUG: Tremelimumab|DRUG: MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Clarithromycin|DRUG: Clofazimine|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prevent It 2.0/GPP -iCBT to Reduce the Risk of Committing Child Sexual Abuse
Status: RECRUITING
Conditions: Pedophilia
Interventions: OTHER: Prevent It 2.0|OTHER: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture (VITAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Density|Body Composition|Bone Health
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 placebo|DIETARY_SUPPLEMENT: Fish oil placebo|DIETARY_SUPPLEMENT: omega-3 fatty acids (fish oil)|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt)
Status: RECRUITING
Conditions: Nontuberculous Mycobacterial Pulmonary Infection|Outbreak Investigation|Healthcare Associated Infection|Mycobacterium Infections
Interventions: OTHER: Epidemiologic investigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VPA Expanded UCB Transplantation for Treatment of Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Hematological Malignancy|Acute Leukemia in Remission|Acute Lymphoblastic Leukemia in Remission|Myelodysplastic Syndromes|Non-Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: BIOLOGICAL: Cord blood stem cells|DRUG: Valproic Acid|DRUG: Fludarabine|DRUG: cytoxan|DRUG: Thiotepa|BIOLOGICAL: TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib for Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplantation (HCT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Cancer
Interventions: DRUG: ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction
Status: UNKNOWN
Conditions: Refractive Errors|Vision Disorders
Interventions: DEVICE: EQ103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: tDCS as an add-on Treatment for Resistant Major Depression in Uni- or Bipolar Patients
Status: COMPLETED
Conditions: Resistant Depression|Moods Disorders|Unipolar Depression|Bipolar Disorder
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS) (Eldith DC NeuroConn Stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Direct Current Stimulation for Cognition in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Psychosis
Interventions: DEVICE: Active Trans-cranial direct-current stimulation|DEVICE: Sham Trans-cranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Gastrointestinal Stromal Tumor|Locally Advanced Sarcoma|Metastatic Gastrointestinal Stromal Tumor|Metastatic Sarcoma|Stage III Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8|Stage III Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8|Stage IV Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8|Stage IV Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|DRUG: Rogaratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shade Matching of Omnichroma (One Shade Universal Composite) Versus a Microhybrid Composite in Class V Restorations.
Status: UNKNOWN
Conditions: Class V Restorations
Interventions: DRUG: Omnichroma (one shade universal) composite by Tokuyama|DRUG: A microhybrid composite Z250 (3 M ESPE, St. Paul, MN, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis B
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: PEG-Tα1|DRUG: Placebo to match PEG-Tα1|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation
Status: COMPLETED
Conditions: MSS|RAS-mutant Colorectal Cancer
Interventions: DRUG: binimetinib|DRUG: nivolumab|DRUG: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Dietary Fats and Carbohydrate in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Acute Effects of Fats and Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bortezomib for Treating Glomerular Diseases
Status: UNKNOWN
Conditions: Bortezomib|Glomerulonephritis|MN|MPGN|FSGS|IgA Nephropathy
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PSMA-PET and mpMRI in High-risk Prostate Cancer - Using Histopathologic Validation
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: [18F]PSMA-PET|DEVICE: MRI sequences optimized for prostate cancer examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chidamide Plus R-CHOP in Elderly DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Pharmacokinetics, Safety, and Tolerability Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: XG005|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorders|Autism|Asperger's Syndrome|Pervasive Developmental Disability - Not Otherwise Specified|Obsessive-compulsive Disorder|Social Phobia|Generalized Anxiety Disorder|Specific Phobia|Separation Anxiety Disorder
Interventions: BEHAVIORAL: Personalized Cognitive-behavioral therapy|BEHAVIORAL: Standard Practice Cognitive-behavioral therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Routine Antibiotic Use in the Outpatient Treatment of Severely Malnourished Children Without Complications
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: DRUG: Amoxicillin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Mononuclear Cells in Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis Due to Virus C Chronic Hepatitis
Interventions: GENETIC: Autologous bone marrow mononuclear cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Nerve Block|Neuromuscular Blockade
Interventions: PROCEDURE: Local infiltration analgesia|PROCEDURE: Ultrasound-guided adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)
Status: RECRUITING
Conditions: Bulimia Nervosa|Overweight or Obesity
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 7-day Holter Monitoring in Adult Patients With Recent IS or TIA, to Measure the Prevalence of Paroxysmal Atrial Fibrillation Including Episodes Less Than 30 Seconds: Transversal Study
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Adult subjects diagnosed with IS or TIA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coating to Optimize Aneurysm Treatment In The New Flow Diverter Generation
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Endovascular treatment of unruptured aneurysms with p64 MW HPC Flow Modulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease
Status: RECRUITING
Conditions: Obesity|Chronic Kidney Diseases
Interventions: DRUG: RAS inhibitors：Losartan®️/Valsartan®️|DRUG: dapagliflozin：Forxiga®️|DRUG: simagliptin：Forxiga®️
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Head and Neck Cancer|Non Small Cell Lung Cancer|Gastrointestinal Cancer|Triple Negative Breast Cancer|Ovarian Carcinoma
Interventions: DRUG: TJ004309
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Naproxen on Heterotropic Bone Formation Following Hip Arthroscopy
Status: COMPLETED
Conditions: Heterotopic Ossification
Interventions: DRUG: Naproxen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of JointAlive™ on the Knee-joint Function in Adults With Knee Arthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DIETARY_SUPPLEMENT: JointAlive™|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Health Effect of Diet Rich in Nordic Berries
Status: COMPLETED
Conditions: Metabolic Syndrome|Impaired Glucose Tolerance|Low-grade Inflammation|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: 300 g of strawberry, raspberry and cloudberry|DIETARY_SUPPLEMENT: 400 g of bilberry|OTHER: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT