pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comprehensive Molecular Diagnosis and Management of Hospital- and Ventilator-associated Pneumonia in Norway
Status: RECRUITING
Conditions: Pneumonia, Ventilator-Associated|Hospital-acquired Pneumonia|Infectious Disease|Infection, Hospital|Antibiotic Resistant Infection
Interventions: DIAGNOSTIC_TEST: Molecular diagnostics in HAP and VAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Community-Based Nutrition-Lifestyle Therapy for Pregnant Latina Women With Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetes Mel Gestational - in Pregnancy
Interventions: BEHAVIORAL: Nutrition-behavior lifestyle program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Facilitating MAT Acceptance & Implementation in Problem Solving & Felony Courts
Status: UNKNOWN
Conditions: Improving Treatment for Opioid Use Disorder in Courts
Interventions: BEHAVIORAL: eLearning Modules|BEHAVIORAL: Change Team Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Semorinemab in Patients With Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Semorinemab|DRUG: Placebo|DRUG: [18F]GTP1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso
Status: UNKNOWN
Conditions: Malignant Mesothelioma|Pancreatic Cancer|Ovarian Tumor|Triple Negative Breast Cancer|Endometrial Cancer|Other Mesothelin Positive Tumors
Interventions: BIOLOGICAL: anti-meso-CAR vector transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: ARO-HBV|OTHER: Sterile Normal Saline (0.9% NaCl)|DRUG: JNJ-56136379
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leaderboard Influence on Self-Regulated Training in a Gamified Dermoscopy Training App
Status: RECRUITING
Conditions: Melanoma (Skin)|Skin Cancer
Interventions: OTHER: Daily updated ranking on leaderboard|OTHER: Daily motivational message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1b, Open-Label, Dose-Finding Study to Evaluate the Safety of Tivozanib (AV-951) in Combination With Temsirolimus in Subjects With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: tivozanib (AV-951) plus temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy Combined With Anti-PD-1 Antibody in Metastatic Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Dacomitinib in NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC Stage IIIB|NSCLC Stage IIIC|NSCLC Stage IV|Recurrent NSCLC|EGFR Positive Non-Small Cell Lung Cancer
Interventions: DRUG: Dacomitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: electrical stimualtion via EmeTerm bracelet|DRUG: antimetic drugs（ dexamethasone，ondansetron）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Laser Acupuncture on Zanzhu (BL02) for Dry Age-related Macular Degeneration
Status: ENROLLING_BY_INVITATION
Conditions: Age-related Macular Degeneration
Interventions: DEVICE: laser acupuncture|DEVICE: sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation and External-Beam Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: radiofrequency ablation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies
Status: COMPLETED
Conditions: Graves' Ophthalmopathy
Interventions: DRUG: Carbimazole, radio-active iodine (I131)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Comfort Level During Orogastric Catheter Insertion in Preterms
Status: COMPLETED
Conditions: Prematurity|Pain Acute|Comfort|Orogastric Tube Insertion
Interventions: OTHER: breast milk|OTHER: dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Docosahexanoic Acid Supplementation in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Docosahexanoic Acid Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Incorporating Lean Beef Into a Protein-rich Diet During Resistance Training on Muscle and Tendon Strength in Older Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcopenia|Aging
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.
Status: COMPLETED
Conditions: Advanced Gastrointestinal Tumors
Interventions: DRUG: TAS-102|DRUG: CPT-11|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Endarterectomy vs Remote Endarterectomy + Drug Coated Balloon (DCB) Angioplasty in Patients With the Femoral Artery Occlusive Disease
Status: UNKNOWN
Conditions: Femoral Artery Occlusion
Interventions: PROCEDURE: Remote endarterectomy|PROCEDURE: Remote endarterectomy + DCB balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Therapeutic Inertia Among Adults Recently Diagnosed With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Physician Education|OTHER: Accountable Population Manager outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: bempedoic acid 180mg|OTHER: placebo|DRUG: evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunotherapy Study for Brain Cancer
Status: COMPLETED
Conditions: Gliomas|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Mixed Glioma|Glioblastoma Multiforme|Malignant Meningioma
Interventions: DRUG: alloreactive CTL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cold Dissection Technique and Needle Monopolar Electrocautery Tonsillectomy
Status: UNKNOWN
Conditions: Chronic Tonsillitis|Tonsillectomy|Tonsillar Hypertrophy
Interventions: PROCEDURE: Tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Late Postoperative Course of Patients With Mini Video Assisted Thyroidectomy (miVAT) Versus Classic Thyroidectomy (T)
Status: COMPLETED
Conditions: Goiter
Interventions: PROCEDURE: Total Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Loneliness Epidemic Tailoring Interventions to Reduce Loneliness and Pain
Status: COMPLETED
Conditions: Pain, Chronic|Loneliness
Interventions: BEHAVIORAL: Conversational Voice Assistant-Enhanced|BEHAVIORAL: Conversational Voice Assistant-Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Trial of Flexible Doses of Oral Ziprasidone in Children and Adolescents With Bipolar I Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: placebo oral capsules|DRUG: ziprasidone oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effectiveness of Online Self-help for Parents of Children With Food Allergies
Status: COMPLETED
Conditions: The Well Being of Parents of Children With Food Allergies
Interventions: OTHER: Online self-help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of the Octapolar Lead in Patients With Failed Back Surgery Syndrome (FBSS) With Chronic Pain
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: Spinal cord stimulation with eight polar electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: DRUG: Dexamethasone|OTHER: No dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double Blind, Placebo Controlled Trial L-carnitine and Piracetam in the Treatment of Weakness, Muscle Fatigue and Muscle Pain in the Postpoliomyelitis Syndrome
Status: WITHDRAWN
Conditions: Postpoliomyelitis Syndrome
Interventions: DRUG: L-carnitine and piracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Stratified Sequential Treatment for CD20-positive PTLD
Status: COMPLETED
Conditions: PTLD|Posttransplant Lymphoproliferative Disorder
Interventions: DRUG: rituximab monotherapy|DRUG: sequential R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phendimetrazine and Cocaine
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Cocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers of Angiogenesis and Disease in Patients With Unresectable Malignant Mesothelioma Treated on Clinical Trial CALGB-30107
Status: TERMINATED
Conditions: Malignant Mesothelioma
Interventions: OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Extubation to NIPPV|PROCEDURE: Extubation to CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy
Status: UNKNOWN
Conditions: Infant, Premature, Diseases|Hypoxia|Necrotizing Enterocolitis
Interventions: DEVICE: Near Infrared Spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PVP Iodine Effect on Post Debridement Bacteraemia
Status: COMPLETED
Conditions: Bacteraemia Post Debridement
Interventions: DRUG: Supra- and subgingival rinsing with 10% PVP-iodine|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: UB-421 Combine With Optimized Background Therapy Regimen in Multi-Drug Resistant HIV-1 Infection Patients
Status: UNKNOWN
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: UB-421|DRUG: Optimized background therapy (OBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SIR-Spheres Study to Calculate the Radiation-Absorbed Dose of 99mTc-MAA
Status: COMPLETED
Conditions: Carcinoma|Carcinoma, Hepatocellular|Liver Neoplasm
Interventions: DRUG: 99mTc-Macro Albumin Aggregate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Active Cycle of Breathing Technique With and Without Acapella on Airway Clearance
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Acapella,ACBTS|OTHER: ACBTs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extracellular Vesicles and Endothelial Function in Transgender Subjects
Status: UNKNOWN
Conditions: Transgenderism
Interventions: DRUG: gender affirming hormonal treatment in transgender men|DRUG: gender affirming hormonal treatment in transgender women
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Advanced Solid Tumors|Cancer|Cancer of Pancreas|Cancer of the Pancreas|Metastases|Metastatic Cancer|Metastatic Pancreatic Cancer|Pancreas Cancer|Pancreatic Cancer|Bone Metastases|Endocrine Cancer|Oncology|Oncology Patients|Solid Tumors|Advanced Malignancy
Interventions: DRUG: AMG 479|DRUG: Placebo|DRUG: AMG 479|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequentially Administered CPT-11 and Mitomycin C in Patients With Advanced Esophageal and Stomach Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Esophagus Cancer|Cancer of Stomach|Stomach Cancer
Interventions: DRUG: CPT-11|DRUG: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Significance of Complexity Measures in the Sensory-motor Behavior
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Wrist anesthesia|OTHER: Blinding mask|OTHER: Anti-noise helmet|OTHER: Tapping test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment
Status: COMPLETED
Conditions: Effect of Drug
Interventions: DRUG: post operative analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients of South Asian Descent
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Metabolic Syndrome|Cardiovascular Disease|Diastolic Dysfunction|Fatty Liver
Interventions: DRUG: Liraglutide|DRUG: Liraglutide - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: αPD1-MSLN-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Autophagy in Patients With Advanced/Recurrent Non-small Cell Lung Cancer - Phase II
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Advanced Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Hydroxychloroquine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON
Status: TERMINATED
Conditions: Autosomal Dominant Polycystic Kidney|ADPKD
Interventions: DRUG: Bardoxolone methyl oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Program:Lenalidomide With or Without Dexamethasone In Previously Treated Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Executive Dysfunction
Interventions: DEVICE: Computer-based cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Absolute Bioavailability of YH4808 With Accelerator Mass Spectrometry(AMS)-Based Microdose Study
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: YH4808 PO and [14C]-YH4808 IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 18F-PSMA-1007 PET Imaging to Detect Primary Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: 18F-PSMA-1007 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Stress Neuromodulators in Decision Making Under Risk and Selective Attention to Threat
Status: COMPLETED
Conditions: Yohimbine|Hydrocortisone|Yohimbine + Hydrocortisone|Placebo
Interventions: DRUG: "Yohimbine"|DRUG: "Hydrocortisone"|DRUG: "Yohimbine + Hydrocortisone"|DRUG: "Placebo"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess the Efficacy and Safety of PT010 Compared to PT009 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: BGF 320/14.4/9.6 µg MDI|DRUG: BFF 320/9.6 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of 2% Lidocaine Gel for Intrauterine Device (IUD) Insertion
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 2% lidocaine gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction and Recognition of Emotions
Status: WITHDRAWN
Conditions: Healthy Older Adults|Alzheimer's Disease|Parkinson's Disease
Interventions: DIAGNOSTIC_TEST: Mini Cognitive Examination (MCE)|DIAGNOSTIC_TEST: Beck Depression Inventory-II (BDI-II)|DIAGNOSTIC_TEST: Global Deterioration Scale (GDS)|DIAGNOSTIC_TEST: Memory alteration test (M@T)|DIAGNOSTIC_TEST: Spanish-Complutense Verbal Learning Test (TAVEC)|DIAGNOSTIC_TEST: Barcelona test (BT)|DIAGNOSTIC_TEST: Rey-Osterrieth Complex Figure Test (ROCFT)|DIAGNOSTIC_TEST: Frontal assessment battery (FAB)|DIAGNOSTIC_TEST: Positive and Negative Affect Scale (PANAS)|DIAGNOSTIC_TEST: Auto-Assessment Manikins (SAM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemtuzumab Ozogamicin Before Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Allogeneic Transplantation
Interventions: DRUG: Gemtuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Intervention to Improve Adherence in Teens With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease
Interventions: BEHAVIORAL: 2 Family-based problem solving phone sessions|BEHAVIORAL: 4 Family-based problem solving phone intervention sessions|BEHAVIORAL: Wait list comparison group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Trial Combining Zidovudine, Interferon-alfa, and Recombinant CD4-IgG With Transplantation of Syngeneic Bone Marrow and Peripheral Blood Lymphocytes From Healthy gp160-Immunized Donors in the Treatment of Patients With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CD4-IgG|DRUG: Zidovudine|DRUG: Interferon alfa-n1|PROCEDURE: Peripheral lymphocyte infusion|PROCEDURE: Bone marrow transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Metabolism, Excretion and Pharmacokinetics of [14C]AZD1981 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1981
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Novel Ibuprofen|DRUG: Standard Ibuprofen|DRUG: Standard Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of HMOs on Faecal Microbiota, Gastrointestinal Symptoms, Mucosal Immunity and Barrier Function in IBS Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DIETARY_SUPPLEMENT: HMO1|DIETARY_SUPPLEMENT: HMO2|DIETARY_SUPPLEMENT: Dextropur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Non-inferiority of Cavir in HBeAg(+)Chronic Hepatitis B Patients Treated With Baraclude
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Cavir|DRUG: Baraclude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-prandial Glucose in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: no added plant-based ingredients to starchy meal|DIETARY_SUPPLEMENT: Low level plant-based ingredients added to starchy meal|DIETARY_SUPPLEMENT: Medium level plant-based ingredients added to starchy meal|DIETARY_SUPPLEMENT: High level plant-based ingredients added to starchy meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With BRCA Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Breast Cancer
Interventions: DRUG: Olaparib tablets, 150 mg|DRUG: Lynparza® (olaparib) tablets 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Telotristat etiprate|DRUG: Octreotide LAR Depot|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Esomeprazole 20 Milligram (mg) Delayed-Release Capsules in Healthy Adult Participants
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DRUG: Esomeprazole 20 mg Delayed-Release Capsules|DRUG: Esomeprazole 20 mg Delayed-Release Capsules (Nexium 24HR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Time Course Change in Skeletal Muscle and Blood Phospholipid Composition With Omega-3 Fatty Acid Supplementation
Status: RECRUITING
Conditions: Skeletal Muscle Fatty Acid Metabolism
Interventions: DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fecal Microbiota Transplantation in Recurrent or Refractory Clostridium Difficile Colitis
Status: UNKNOWN
Conditions: Clostridium Difficile|Clostridium Difficile Infection
Interventions: BIOLOGICAL: FMT|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Antitumor Activity of a Thorium-227 Labeled Antibody-chelator Conjugate Alone and in Combination With Darolutamide, in Patients With Metastatic Castration Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: BAY2315497 Injection|DRUG: Darolutamide(BAY1841788)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of BI 1181181 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1181181 high dose|DRUG: BI 1181181 low dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Neoplasm|Pancreatic Adenocarcinoma|Borderline Resectable Pancreatic Adenocarcinoma
Interventions: DRUG: mFOLFIRINOX or Gemcitabine nab-paclitaxel|RADIATION: Isotoxic High-Dose (iHD)-SBRT|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Myo-inositol + folic acid + melatonin|DIETARY_SUPPLEMENT: Myo-inositol + folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Urinary Tract Infection|Asymptomatic Bacteriuria
Interventions: DRUG: Fosfomycin disodium|DRUG: Trimethoprim / Sulfamethoxazole|DRUG: Intravenous placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: green tea extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Oral [14C]PF-07081532|DRUG: Oral PF-07081532 and IV [14C]PF-07081532
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peri-operative Chemotherapy With ECX or XP in the Treatment of Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Peri-operative chemotherapy of ECX|DRUG: Peri-operative chemotherapy of XP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)
Status: TERMINATED
Conditions: Hypercholesterolemia, Familial|Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: MK-0524A|DRUG: MK-0524A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study Evaluating the Prevalence of Enzyme Deficiency in Pulmonology Clinics (ADA)
Status: UNKNOWN
Conditions: Bronchiectasis|Adenosine Deaminase Deficiency|Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: adenosine deaminase enzyme deficiency test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Games of WonderTree Augmented Reality|OTHER: Traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD
Status: RECRUITING
Conditions: Opioid Use Disorder|Pregnancy Related|Substance Use|Drug Abuse|Drug Abuse in Pregnancy|Drug Addiction
Interventions: BEHAVIORAL: Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Sequence and Imaging Protocol Development
Status: UNKNOWN
Conditions: Cardiomyopathy, Hypertrophic|Cardiomyopathy, Dilated|Left Ventricular Hypertrophy|Ischemic Heart Disease|Hypertension
Interventions: OTHER: Cardiovascular Magnetic Resonance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Hysterectomy - Outpatient Versus Inpatient Regimen
Status: COMPLETED
Conditions: Outpatient Hysterectomy
Interventions: PROCEDURE: Total laparoscopic hysterectomy|PROCEDURE: Total laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Administration of Antibiotics in Patients Undergoing Surgery for Colorectal Cancer Result in Less Complications and Better Prognosis?
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Selective decontamination of the digestive tract (SDD) (colistin sulfate, tobramycin, amphotericin B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Full-mouth and Partial-mouth Scaling and Root Planing in Type 2 Diabetic Subjects
Status: COMPLETED
Conditions: Periodontitis|Diabetes
Interventions: PROCEDURE: FMSRP|DRUG: Chlorhexidine|PROCEDURE: PMSRP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Biweekly Pemetrexed and Gemcitabine in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: pemetrexed|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy for Postoperative Nausea and Vomiting in Laparoscopic Gastrointestinal Surgery
Status: COMPLETED
Conditions: C.Surgical Procedure; Gastrointestinal
Interventions: DRUG: palonosetron, dexamethasone, and fosaprepitant dissolved in 0.9% NaCl|DRUG: palonosetron, dexamethasone, and 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: hATG+CsA vs hATG+CsA+Eltrombopag for SAA
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: hATG|DRUG: CsA|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentre Study in Four Parallel Groups of Parkinson's Disease (PD) Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: BIA 9-1067|DRUG: BIA 9-1067|DRUG: BIA 9-1067|DRUG: Levodopa/Carbidopa|DRUG: Levodopa/Benzerazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciprofloxacin XR Drug Interaction Study With MMX® Mesalazine/Mesalamine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ciprofloxacin XR + MMX Placebo|DRUG: MMX Mesalazine/mesalamine + Ciprofloxacin XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bromfenac Versus Dexamethasone After Cataract Surgery
Status: COMPLETED
Conditions: Inflammation Eye
Interventions: DRUG: Bromfenac 0.09 % Ophthalmic Solution|DRUG: Dexamethasone 0.1% ophthalmic suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Gendolcat Score for the Prognosis of Chronic Postoperative Pain in Cesarean Section
Status: RECRUITING
Conditions: Chronic Post Surgical Pain|Cesarean Section Complications|Chronic Pain
Interventions: OTHER: Questionnaire|OTHER: Questionnaire|OTHER: Questionnaire|OTHER: Questionnaire via telephone call|OTHER: Physical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy
Status: RECRUITING
Conditions: Mediastinal Lymphadenopathy|Sarcoidosis, Pulmonary|Mediastinal Diseases
Interventions: PROCEDURE: Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Risk of Adrenal Insufficiency and Cushing Syndrome Associated With Glucocorticoid Therapy in People With Chronic Inflammatory Diseases
Status: COMPLETED
Conditions: Adrenal; Insufficiency Gluccorticoid-Induced|Cushing; Syndrome or Disease, Glucocorticoid-Induced
Interventions: DRUG: Glucocorticoids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allograft Transplantation in the Treatment of Osteoarthritis of the Metatarsophalangeal (MTP) Joint of the Great Toe
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Meniscal Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Status: RECRUITING
Conditions: Aphasia|Stroke
Interventions: BEHAVIORAL: PICTURE-IT|BEHAVIORAL: CoDeLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Anti-CD19 CAR NK Cells in the Treatment of Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: anti-CD19 CAR NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENIGMA - Evaluation of Nitrous Oxide In the Gas Mixture for Anaesthesia: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Quality of Recovery From Anaesthesia|Effects of Nitrous Oxide Following Anaesthesia|Induced Endothelial Dysfunction
Interventions: DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Study of ASP7374, Cell-culture-derived Influenza Vaccine
Status: COMPLETED
Conditions: Influenza|Vaccine
Interventions: BIOLOGICAL: ASP7374|BIOLOGICAL: approved egg-derived TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Performance of Short- and Long-term Baseplates for Attaching the Marco Recorder
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DEVICE: Baseplates with two types of adhesives are tested: 3M 1522 & Nitto ST-2410WD|DEVICE: Baseplates with two types of adhesives are tested: Amparo 130002 & 3M 2480
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intensive FMT on Primary Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: BIOLOGICAL: FMT capsules|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Energy Dose Study
Status: TERMINATED
Conditions: Critical Illness
Interventions: DRUG: Parenteral Nutrition|DRUG: Propofol|DRUG: Clevidipine|DRUG: Dextrose-containing IV Fluids|DRUG: Enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastasis
Interventions: OTHER: General health survey questionnaires|OTHER: PROMIS Cancer Function Brief 3D profile questionnaires|OTHER: FACT-G questionnaires|OTHER: Godin Leisure-Time Exercise Questionnaire|OTHER: REAP-S questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efbemalenograstim Alfa Injection for Ovarian or Cervical Cancer Receiving Chemotherapy Regimen
Status: RECRUITING
Conditions: Ovarian Cancer|Cervical Cancer
Interventions: DRUG: Efbemalenograstim Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandibular Advancement vs Home Treatment for Primary Snoring
Status: COMPLETED
Conditions: Snoring
Interventions: DEVICE: Interventional Arm|COMBINATION_PRODUCT: Conservative treatment Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Therapy Selected by Molecular/Metabolic Profiling in Patients With Previously Treated Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Previously Treated Metastatic Pancreatic Cancer
Interventions: DRUG: Drug will be recommended based on IHC/Fish, CGH and Pan-XenoBank
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5083945 in Combination With Chemotherapy Versus Chemotherapy Alone in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: RO5083945|DRUG: cisplatin|DRUG: gemcitabine|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Monoclonal Antibody in Combination With Chemotherapy in Patients With RR NHL
Status: UNKNOWN
Conditions: Relapsed/Refractory Non-Hodgkin's Lymphoma
Interventions: DRUG: PD-1 combined with chemotherapy|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Dyspepsia
Interventions: DEVICE: Esophageal Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Cardiovascular Diseases
Interventions: PROCEDURE: supplementation with betaine, serine, and folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Selective Internal Radiotherapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Cholangiocellular Carcinoma (CCC).
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocellular Carcinoma
Interventions: PROCEDURE: DEB TACE|PROCEDURE: SIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: split-course hypofraction radiotherapy|DRUG: CAPOX|DRUG: Envafolimab|PROCEDURE: Local excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic as Single Shot Versus Catheter in Patients Undergoing Video Assisted Thoracoscopic Surgery
Status: SUSPENDED
Conditions: Thoracic Surgery
Interventions: DRUG: Liposomal Bupivacaine (EXPAREL®)/Bupivacaine|DRUG: Ropivacaine (0.5% bolus followed by 0.2% infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Ventilation in Pulmonary Edema
Status: COMPLETED
Conditions: Pulmonary Edema|Myocardial Infarction
Interventions: DEVICE: CPAP and Non Invasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Risk Registry of Endoscopic Image and Pathology Correlation for Fujiflim
Status: COMPLETED
Conditions: Gastro-Intestinal Disorder
Interventions: DEVICE: Fuji Flim Processor VP-7000, Light Source BL-7000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Aortic Biobank of POP-STAR
Status: ENROLLING_BY_INVITATION
Conditions: Abdominal Aortic Aneurysm Without Rupture|Abdominal Aortic Aneurysm, Ruptured|Aortic Aneurysm|Aneurysm Abdominal|Aneurysm
Interventions: DIAGNOSTIC_TEST: Structured imaging follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p