pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetic Bioequivalence Study of Nebcinal® 150mg/3ml Administered by Aeroneb® Idehaler® Versus Tobi® 300mg/5ml Administered by Pari LC Plus®
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Nebcinal Tobi|DRUG: Tobi Nebcinal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leg Heat Therapy in Peripheral Artery Disease
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Leg heat therapy|DEVICE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours
Status: COMPLETED
Conditions: Hyperopia|Myopia
Interventions: DEVICE: Lotrafilcon B|DEVICE: lotrafilcon B with Hydraluxe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Perception Associated With Orogastric Tube Insertion in Preterm Infants
Status: UNKNOWN
Conditions: Orogastric Tube Insertion
Interventions: OTHER: White Noise|OTHER: Swaddling Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: fondaparinux sodium injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 15141 Fixed Dose Correction / naïve and Pre Dialysis (Europe and Asia Pacific)
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic
Interventions: DRUG: BAY85-3934|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BCG Vaccine for Health Care Workers as Defense Against COVID 19
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronavirus|Coronavirus Infection|Coronavirus as the Cause of Diseases Classified Elsewhere
Interventions: BIOLOGICAL: BCG Vaccine|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Infusion Site Pain After Infusion of Excipients in Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Sodium Citrate|DRUG: Treprostinil|DRUG: Humalog diluent|DRUG: Magnesium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Piperacillin/Tazobactam for Empirical Therapy of Febrile Neutropenia
Status: COMPLETED
Conditions: Febrile|Neutropenia|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Piperacillin-tazobactam combination product|DRUG: Imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3478045 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3478045|DRUG: Placebo|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide and Sintilimab for Relapsed/Refractory NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: NK/T Cell Lymphoma Nos
Interventions: DRUG: Sintilimab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Symbicort® as an add-on Treatment to Spiriva® in Patients With Severe COPD.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease, COPD
Interventions: DRUG: Symbicort (budesonide/formoterol turbuhaler 320/9ug)|DRUG: Spiriva (tiotropium bromide 18ug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of DA-5204
Status: UNKNOWN
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: DA-5204|DRUG: Stillen tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo
Status: RECRUITING
Conditions: Hernia, Paraesophageal
Interventions: DRUG: IV lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial Comparing Corifollitropin-alfa Late Start vs. Corifollitropin-alfa Standard Start in Expected Poor, Normal and High-responders Undergoing IVF
Status: COMPLETED
Conditions: Fertility Disorders
Interventions: DRUG: Corifollitropin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Structural Changes in Airways, Measured by MSCT, of Twice Daily 60mg AZD9668 for 12 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: AZD9668|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the KLOX BioPhotonic OraLum Gel With a LED Curing Lamp in Moderate to Severe Chronic Periodontitis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Periodontitis
Interventions: DEVICE: KLOX BioPhotonic OraLum Gel|PROCEDURE: Scaling and Root Planing (SRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Gastric Cancer
Status: RECRUITING
Conditions: Malignant Neoplasm of Stomach
Interventions: PROCEDURE: D2 radical gastrectomy|DRUG: SOX neoadjuvant or postoperative chemotherapy|PROCEDURE: Hyperthermic intraperitoneal chemotherapy (HIPEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
Status: COMPLETED
Conditions: Skin Aging
Interventions: BIOLOGICAL: Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)
Status: NOT_YET_RECRUITING
Conditions: Hemangioendothelioma of Liver
Interventions: DRUG: Sirolimus Oral Product|DRUG: propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liquid Bandage (2-Octyl-Cyanoacrylate) in Upper Lid Blepharoplasty
Status: TERMINATED
Conditions: Blepharoptosis
Interventions: PROCEDURE: Bilateral Upper eyelid blepharoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment
Status: RECRUITING
Conditions: Cervical High Grade Squamous Intraepithelial Lesion|Cervical Intraepithelial Neoplasia Grade 2/3|CIN 2/3|Cervical Intraepithelial Neoplasia
Interventions: DRUG: Imiquimod|DIAGNOSTIC_TEST: 3x vaginal swab for microbiome analysis|OTHER: Expectative management|DIAGNOSTIC_TEST: 2x vaginal swab for microbiome analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neonatal Hypoxic Ischemic Encephalopathy : Safety and Feasibility Study of a Curative Treatment With Autologous Cord Blood Stem Cells
Status: RECRUITING
Conditions: Neonatal Hypoxic-ischaemic Encephalopathy
Interventions: DRUG: autologous cord blood stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Surface Imaging Versus Conventional Photography as a Tool to Document the Surface Geometry of Pectus Excavatum
Status: COMPLETED
Conditions: Pectus Excavatum|Funnel Chest
Interventions: DIAGNOSTIC_TEST: 3D scan|DIAGNOSTIC_TEST: Standard photography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dulaglutide and Insulin MicrosecretiON in Type 1 Diabetes
Status: COMPLETED
Conditions: Adult Subjects With Type1Diabetes and Insulin Microsecretion
Interventions: DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Flavonoids on Intestinal Microbiota, Intestinal Inflammation and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X|Inflammation
Interventions: OTHER: High Dietary Flavonoids|OTHER: Low Dietary Flavonoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair Defects
Status: COMPLETED
Conditions: Castration Resistant Prostatic Cancer|Metastatic Prostate Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Impact of Predicting Early Pregnancy Outcomes in Women With Pregnancy of Uncertain Viability
Status: UNKNOWN
Conditions: Uncertain Viability of Pregnancy|Anxiety|Depression
Interventions: DIAGNOSTIC_TEST: Prediction of pregnancy outcome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized, Prospective Study of the Efficacy, Safety and Tolerability of Two Doses of GW433908Ritonavir Given With Abacavir/Lamivudine Fixed Dose Combination
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: fos-amprenavir calcium, ritonavir|DRUG: abacavir/lamivudine as Epzicom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Different Doses of a Novel Treatment for Onychomycosis
Status: COMPLETED
Conditions: Distal, Subungual Onychomycosis
Interventions: DRUG: AN2690, 2.5%|DRUG: AN2690, 5%|DRUG: AN2690, 7.5%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Mometasone on Beta-adrenergic Airway and Airway Vascular Relaxation in Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: placebo|DRUG: mometasone 400 mcg|DRUG: mometasone 200 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
Status: RECRUITING
Conditions: Peritoneal Dialysis-associated Peritonitis|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open Label Study of the Safety and Contraceptive Efficacy of BufferGel® With Diaphragm
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Drug: BufferGel® with diaphragm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of Manual Therapy for the Prevention of Radiation-Induced Fibrosis in Patients With Head and Neck Cancer
Status: RECRUITING
Conditions: Radiation-Induced Fibrosis in Patients With Head and Neck Cancer
Interventions: PROCEDURE: manual therapy|PROCEDURE: Speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Proof of Concept ELectro-Stimulation of Muscles to resolVe Insulin Resistance in NASH
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|Insulin Sensitivity
Interventions: DEVICE: Electro-muscular stimulation using NeuroTrac MyoPlus 2/4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injecting Plasma-rich Platelets & Hyaluronic Acid for Patients With Stress Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Stress Incontinence, Female
Interventions: PROCEDURE: PRP injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ezetimibe Tablets Under Fasting Conditions in Healthy Subjects
Status: UNKNOWN
Conditions: Pharmacokinetics|Safety
Interventions: BEHAVIORAL: Test Preparation-Reference preparation|BEHAVIORAL: Reference preparation-Test Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methylprednisolone|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of O-type Hybrid Knife and IT Knife in ESD
Status: COMPLETED
Conditions: Esophageal Cancer|Esophageal Dysplasia|Stomach Cancer|Stomach Dysplasia
Interventions: DEVICE: Hybrid knife|DEVICE: IT knife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of the Application of BeGraft Peripheral Stent Graft System
Status: ACTIVE_NOT_RECRUITING
Conditions: Iliac Artery Stenosis
Interventions: DEVICE: Treatment of primary iliac artery stenosis and/or occlusive lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)
Status: UNKNOWN
Conditions: Muscular Diseases|Spinal Muscular Atrophy
Interventions: DEVICE: Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local vs Systemic Methotrexate in Management of Uterine Ectopic Pregnancy
Status: RECRUITING
Conditions: Local|Systemic|Methotrexate|Uterine Ectopic Pregnancy
Interventions: DRUG: Systemic Methotrexate|DRUG: Local Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Graded Activity and Pain Education (GAPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castrate Resistant Prostate Cancer
Interventions: DRUG: Docetaxel|RADIATION: Radium 223
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study
Status: COMPLETED
Conditions: Carotid Arteries
Interventions: DRUG: PET/CT Imaging with [F-18] RGD-K5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/Ib Study of GWN323 Alone and in Combination With PDR001 in Patients With Advanced Malignancies and Lymphomas
Status: COMPLETED
Conditions: Solid Tumors|Lymphomas
Interventions: DRUG: GWN323|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Efficacy of Pascoflair in an Acute Stressful Situation (TSST)
Status: COMPLETED
Conditions: Healthy|Stress
Interventions: DRUG: Passiflora incarnata|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Lumigan® 0.01% Treatment for Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01% ophthalmic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BIOLOGICAL: Glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of TBCT, MBHP and PPT for PTSD During the Covid-19 Pandemics
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder|Covid19
Interventions: BEHAVIORAL: Trial-Based Cognitive Therapy|BEHAVIORAL: Mindfulness-Based Health Promotion|BEHAVIORAL: Positive psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Patients With Function Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia|Postprandial Distress Syndrome
Interventions: OTHER: acupuncture|OTHER: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study
Status: COMPLETED
Conditions: Fluid Overload
Interventions: OTHER: oxytocin and spinal anesthesia|OTHER: General anesthsia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, PK and PD of HNC364 Injectable Suspension
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: HNC364|DRUG: HNC364|DRUG: HNC364|DRUG: HNC364
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Observational Study to Evaluate Apligraf(R) in Nonhealing Wounds of Subjects With Epidermolysis Bullosa
Status: TERMINATED
Conditions: Epidermolysis Bullosa|Wound Healing
Interventions: DEVICE: Apligraf
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOW EVAL-AF: FLOW Mapping Electrogram VALidation in Patients With Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Longstanding Persistent Atrial Fibrillation|Atrial Fibrillation, Persistent|Arrhythmias, Cardiac
Interventions: DEVICE: Electrographic Flow™ Mapping using Ablamap® Software and FIRMap™ Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerability, Safety and Pharmacokinetic Study of Humanized Anti-CD6 Monoclonal Antibody Injection in Chinese Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: BIOLOGICAL: T1h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASPIRE Health Tulare County
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Tract Diseases|Cardiovascular Diseases
Interventions: OTHER: DIY portable air cleaner with a highly effective filter|OTHER: DIY portable air cleaner with sham filtration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Acute Stroke: Prehospital Versus In-HospitAL Initiation of Recanalization Therapy- ASPHALT
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: Mobile Stroke Unit deployment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction
Status: COMPLETED
Conditions: Breast Reconstruction|Anesthesia|Transverse Abdominis Plane Block
Interventions: DRUG: Liposomal bupivacaine|DRUG: Regular bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients' First Degree Relatives
Status: UNKNOWN
Conditions: Parkinson Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and Didanosine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acids on Insulin Sensitivity in Chinese Gestational Diabetic Patients
Status: UNKNOWN
Conditions: Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Flaxseed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: XELOX and XELIRI Alternative Regimen as First-line Treatment for Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Chemotherapy
Interventions: DRUG: XELIRI|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Caudal Block, Ultrasound Guided Caudal Block and Ultrasound Guided Erector Spinae Block for Pediatric Hip Surgery
Status: UNKNOWN
Conditions: Conventional Caudal Block|Ultrasound Guided Caudal Block|Ultrasound Guided Erector Spinae Block|Pediatric Hip Surgery
Interventions: PROCEDURE: Conventional caudal block|PROCEDURE: Ultrasound-guided caudal block|PROCEDURE: Ultrasound guided erector spinae plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Formoterol-beclomethasone in Patients With Bronchiectasis: a Randomized Controlled Trial
Status: TERMINATED
Conditions: Bronchiectasis
Interventions: DRUG: Formoterol-beclomethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine in IVRA
Status: COMPLETED
Conditions: Regional Anesthesia Morbidity
Interventions: DRUG: Dexmedetomidine Injectable Solution [Dexdomitor]|DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers
Status: NOT_YET_RECRUITING
Conditions: MMR-D/MSI-H Colorectal Cancers
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of PF-04447943 On Qtc Interval In Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04447943|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Two Ovulation Induction Therapies and LOD on Clinical Outcomes in CC-Resistant PCOS Women
Status: COMPLETED
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DRUG: Gonadotropin|DRUG: Letrozole|PROCEDURE: laparoscopic ovarian drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Study Of Exemestane (Aromasin) For 5 Years Versus Tamoxifen for 2.5 to 3 Years Followed By Exemestane
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane (Aromasin)|DRUG: tamoxifen + exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afya Credit Incentives for Improved Maternal and Child Health Outcomes in Kenya
Status: UNKNOWN
Conditions: Maternal and Child Health
Interventions: OTHER: Conditional cash transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Minimal Effective Volume (MEV90) of Ropivacaine 0.75% for Ultrasound-guided Transmuscular Quadratus Lumborum Block
Status: UNKNOWN
Conditions: Percutaneous Nephrolithotomy
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Menopause Hormone Therapy In Postmenopausal Women With CSVD And MCI
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases|Postmenopausal Symptoms|Mild Cognitive Impairment|White Matter Hyperintensity
Interventions: DRUG: Estradiol Gel|DRUG: Estradiol Placebo Gel|DRUG: Progesterone Soft Capsule|DRUG: Progesterone Placebo Soft Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Posture and Head Position in Kyphotic Female and Male
Status: COMPLETED
Conditions: Kyphosis Thoracic|Postural, Thoracic Kyphosis|Postural Kyphosis
Interventions: DIAGNOSTIC_TEST: The kyphosis angle|DIAGNOSTIC_TEST: dynamic postural performance|DIAGNOSTIC_TEST: forward head position
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: BBIBP Bivalent Oral Poliomyelitis Vaccine Lot 1|BIOLOGICAL: BBIBP Bivalent Oral Poliomyelitis Vaccine Lot 2|BIOLOGICAL: BioFarma Bivalent Oral Poliomyelitis Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Diphtheria
Interventions: PROCEDURE: Taking of blood samples|BIOLOGICAL: Boostrix|BIOLOGICAL: Adacel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone Metastasis
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Carboplatin, and Trastuzumab and/or Lapatinib in Treating Women With Stage I, Stage II, or Stage III Breast Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: docetaxel|DRUG: lapatinib ditosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Degarelix Neo-Adjuvant Radical Prostatectomy Trial
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Casodex|DRUG: LHRH Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus (ORCHIDEE)
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enhancing a Sustainable Pharmacy-based Immunization Program in Two States
Status: COMPLETED
Conditions: Herpes Zoster|Pneumococcal Infections
Interventions: BEHAVIORAL: Enhanced immunization delivery model|OTHER: Immunization update
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lovastatin and Its ß-hydroxy Acid From Four 600 mg LipoCol Forte® Capsules Compared to That of One 20 mg Mevacor® Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: LipoCol and Mevacor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline Prophylaxis at Vacuum Aspiration Trial
Status: COMPLETED
Conditions: Endometritis
Interventions: DRUG: Doxycycline pre-operatively|DRUG: Doxycycline post-operatively
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Different Vascular Closure Device in TAVI
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Transcatheter Aortic Valve Implantation
Interventions: DEVICE: Vascular closure device (Angio-Seal, Progilde)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Therapy for Elderly Depression
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: PROCEDURE: 10.000lux blue 1 hour every day during three weeks|PROCEDURE: 50lux dim red 1 hour every day during three weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors.
Status: COMPLETED
Conditions: Advanced Solid Tumors, Excluding Breast Cancer
Interventions: DRUG: dovitinib (TKI258)|DRUG: fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Pulmonary Hypertension|Interstitial Lung Disease|Idiopathic Interstitial Pneumonia|Idiopathic Pulmonary Fibrosis|Sarcoidosis|Respiratory Bronchiolitis Associated Interstitial Lung Disease|Desquamative Interstitial Pneumonia|Cryptogenic Organizing Pneumonia|Acute Interstitial Pneumonitis|Idiopathic Lymphoid Interstitial Pneumonia|Idiopathic Pleuroparenchymal Fibroelastosis
Interventions: DRUG: Bardoxolone methyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC585 in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: HEC585|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metal Artifacts Reduction Orotocols and Electric Potential Difference on Metal Artifacts in Cone Beam Computed Tomography
Status: UNKNOWN
Conditions: Metal Artifacts
Interventions: RADIATION: CBCT radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Feasibility Study to Assess the Performance of a Latex Condom in Healthy Monogamous Couples.
Status: UNKNOWN
Conditions: Performance of a New Condom
Interventions: DEVICE: Titan Condom
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Pain Management in Laparoscopic Living-donor Nephrectomy: The Impact of Erector Spinae Plane Block (ESPB) on Perioperative Period
Status: COMPLETED
Conditions: Pain, Postoperative|Donor Site Complication
Interventions: DIAGNOSTIC_TEST: NAS score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Imaging for Significant Prostate Cancer Risk Evaluation
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Prostate HistoScanning|PROCEDURE: Multi-parametric MRI|PROCEDURE: Transperineal prostate mapping biopsy|PROCEDURE: Image guided biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Conservative Versus Liberal Oxygenation Targets in Critically Ill Children
Status: COMPLETED
Conditions: Critical Care|Hypoxia|Pediatric ALL
Interventions: PROCEDURE: Conservative oxygenation target|PROCEDURE: Liberal oxygenation target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm|Myeloproliferative Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Cytarabine|PROCEDURE: Echocardiography|DRUG: Fludarabine|DRUG: Granulocyte Colony-Stimulating Factor|DRUG: Idarubicin|PROCEDURE: Multigated Acquisition Scan|DRUG: Pivekimab Sunirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Adapted Chemotherapy in Patients With Squamous Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of Head and Neck
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Fluoro Uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis
Status: COMPLETED
Conditions: Severe Sepsis With Septic Shock|Severe Sepsis Without Septic Shock
Interventions: DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Brensocatib|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline for Helicobacter Pylori Rescue Treatment
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Bismuth Potassium Citrate|DRUG: Tetracycline|DRUG: Doxycycline|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of GS-3583 in Participants With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: GS-3583|DRUG: Zimberelimab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-Fluorouracil|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Renin Angiotensin System Blockage (RAS), Calcium Channel Blocker and Combined Drugs on TWEAK, PTX3 and FMD Levels in Diabetic Proteinuric Patients With Hypertension
Status: COMPLETED
Conditions: Diabetes|Hypertension|Proteinuria
Interventions: DRUG: Amlodipine|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimal Anemia Treatment in End Stage Renal Disease (ERSD)
Status: UNKNOWN
Conditions: Hyperparathyroidism, Secondary
Interventions: DRUG: standard care|DRUG: Optimal (I. iPTH control: Zemplar®,Mimpara®; phosphorous control: Renvela®, Phoslo®, Osvaren®, Foznol®,Maalox®; calcium control: calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase Activity
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin|DRUG: Insulin Glargine|DRUG: Dorzagliatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary Hypercholesterolemia
Status: UNKNOWN
Conditions: Primary Hypercholesterolemia|Hypertension
Interventions: DRUG: Experimental : Ezetimibe / Rosuvastatin + Telmisartan|DRUG: Active comparator1 : Ezetimibe / Rosuvastatin|DRUG: Active comparator2 : Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Roxolid Implant Material on the Implant Stability Implant Stability
Status: COMPLETED
Conditions: Completely Edentulous Patients
Interventions: DEVICE: Roxolid implants|DEVICE: Titanium implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of Balicatib (AAE581) in Adults With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: balicatib (AAE581)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study Evaluating Mid-position Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Radiation Therapy|Locally Advanced Disease|Non-metastatic Disease|Non-resectable Disease
Interventions: RADIATION: mid-position radiation strategy|RADIATION: ITV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CALMA App as an Adjunct to Therapy for Reduction of Suicidal and Non-Suicidal Self-Injurious Behaviors in Adolescents
Status: RECRUITING
Conditions: Self-Injurious Behavior
Interventions: DEVICE: CALMA m-health app|OTHER: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Disposable Dispensing Clinical Trial of Test Lens Against Stenfilcon A Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: stenfilcon A lens with solution additive (test)|DEVICE: stenfilcon A lens (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Wear of Uncemented Acetabular Conventional Polyethylene and X3 in Total Hip Replacement, for Stereo-radiographic Analysis
Status: UNKNOWN
Conditions: Total Hip Arthroplasty
Interventions: DEVICE: radiostereometric analysis (RSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Proton Versus Photon Beam Radiotherapy in the Treatment of Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: Photon intensity modulated radiation therapy (IMRT)|RADIATION: Proton beam radiotherapy (PBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis Type 1
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Prostatectomy Linac-Based Ultrahypofractionated Radiotherapy for Patients With Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: SBRT|Radical Prostatectomy
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCOUT Reflector for Tagging Lymph Nodes for Targeted Removal in Patients With Breast Cancer
Status: COMPLETED
Conditions: Positive Axillary Lymph Node|Stage 0 Breast Cancer AJCC v6 and v7|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7
Interventions: DEVICE: Implanted Medical Device|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Peripherally Acting µ-opioid Receptor Antagonists on Acute Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DRUG: Placebo treatment|DRUG: Methylnaltrexone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DEVICE: non-coated Intranasal Splint|DEVICE: Sinexus Intranasal Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Video Laryngoscopes in Infants Undergoing Neurosurgery: a Prospective Randomized Clinical Trial
Status: COMPLETED
Conditions: Infant Conditions
Interventions: DEVICE: Airtraq|DEVICE: glidescope|DEVICE: c-mac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: TS-1 and cisplatin|DRUG: TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT