pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Open Label Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing in Human Subjects
Status: COMPLETED
Conditions: Chronic Anal Fissure
Interventions: DRUG: Nifedipine coated suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foot Reflexology on Chronic Pain in Parkinsonian Patients
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: PROCEDURE: reflexology massage|PROCEDURE: sham massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Structural and Functional Left Ventricular Remodelling in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP (continuous positive airway pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Preliminarily Assess the Safety and Feasibility of SAT-014, a Software for Alleviating Symptoms of Trauma and Stress-related Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DEVICE: SAT-014(Software as Medical Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cluster Randomized Controlled Trial Applying Helping Baby Breathe in Nepal
Status: RECRUITING
Conditions: Newborn Morbidity|Newborn Asphyxia|Delivery Preterm
Interventions: OTHER: Simulator based training to manage asphyxia and essential newborn care using neonatalie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Autologous Bone Marrow Derived Mesenchymal Stromal Cells Transplantation(BM-MSC) for Kienbock's Disease
Status: UNKNOWN
Conditions: Kienböck's Disease
Interventions: BIOLOGICAL: BM-MSC transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Efgartigimod in Adults With Post-COVID-19 POTS
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: Efgartigimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QL vs PENG for Analgesia After Hip Arthroplasty
Status: COMPLETED
Conditions: Block|Hip Replacement|Postoperative Pain
Interventions: OTHER: PENG + LFC Block|OTHER: QL Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Radiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Lymphoma or Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 monoclonal antibody MN-14|RADIATION: yttrium Y 90 epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Residual Low Back Pain After Percutaneous Kyphosis(PKP) Using Posterior Branch Block of Spinal Nerve
Status: COMPLETED
Conditions: Osteoporotic Fracture
Interventions: PROCEDURE: posterior branch block of spinal nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, Node Positive, HR+/HER2- Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|RADIATION: Postoperative Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Participation-focused Interventions on Body Functions of Youth With Physical Disabilities
Status: COMPLETED
Conditions: Cerebral Palsy|Spina Bifida|Muscular Dystrophies|Musculoskeletal Disorder
Interventions: BEHAVIORAL: Engagement in 6-week community-based activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Malathion Gel 0.5% and Malathion 0.5% Lotion (Ovide) in Patients With Head Lice
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: Malathion gel 0.5%|DRUG: Malathion lotion 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: [14C]-GSK3191607
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bioavailability of a Spray Dried Dispersion Solid Dose Formulation of PF-06260414 Relative to a Suspension Formulation
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: PF 06260414 solid dose formulation|DRUG: PF-06260414 nanosuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Salba & Flax on Postprandial Glycemia and Subjective Satiety
Status: COMPLETED
Conditions: Hyperglycemia, Postprandial
Interventions: DIETARY_SUPPLEMENT: Salba|DIETARY_SUPPLEMENT: Flax|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|RADIATION: Photon Beam Radiation Therapy|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histological Evaluation in the Efficacy of GentleWave in Root Canal Pulp Tissue Debridement and Disinfection of Difficult to Reach Areas in Mandibular Human Molars II. An In-vivo Study.
Status: RECRUITING
Conditions: Root Canal Treatment
Interventions: DEVICE: GentleWave
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Carcinoma of Unknown Primary|Head and Neck Cancer
Interventions: DRUG: mitomycin C|DRUG: porfiromycin|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Repairing the Defect of Intervertebral Disc With Autologous BMSC and Gelatin Sponge After Microendoscopic Discectomy for Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Lumbar Disc Herniation
Interventions: DEVICE: Autologous Bone Marrow Stem Cell (BMSC)/gelatin sponge|PROCEDURE: The defect is sutured
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Advice, Nicotine Replacement Therapy Sampling and Active Referral (BANSAR) for Smoking Fathers
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Cessation
Interventions: BEHAVIORAL: Brief AWARD advice|DRUG: Nicotine replacement therapy sampling|BEHAVIORAL: Active referral|BEHAVIORAL: Very brief advice|BEHAVIORAL: Leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pyridostigmine and Amifampridine for Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: Pyridostigmine|DRUG: Amifampridine (base) with modified release|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: isolated perfusion|DRUG: paclitaxel|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A PK, Safety and Tolerability Study of Peripheral and Central Infusion of Melflufen in RRMM Patients
Status: TERMINATED
Conditions: RRMM
Interventions: DRUG: Melphalan|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of L-Carnitine in the Management of Acute Carbon Monoxide Poisoning
Status: NOT_YET_RECRUITING
Conditions: Carbon Monoxide Poisoning
Interventions: DIETARY_SUPPLEMENT: L-Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetyl Cysteine for Ovulation Induction in Clomiphene Citrate Resistant Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: N-Acetyl cysteine|PROCEDURE: laparoscopic ovarian drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Effects of GST-HG171 Tablets Combined With Ritonavir in Healthy Chinese Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: GST-HG171/ritonavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safe and Effective Sedation in Chronic Alcoholic Patients Underwent Diagnostic Endoscopic Procedures: Study Comparing Midazolam and Propofol With Midazolam
Status: TERMINATED
Conditions: Chronic Alcoholism
Interventions: DRUG: Midazolam plus propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Lot-consistency Clinical Trial of Sabin Strain Inactivated Polio Vaccine
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Three doses of experimental sIPV of lot 1 at the schedule of 2,3,4 months of age|BIOLOGICAL: Three doses of experimental sIPV of lot 2 at the schedule of 2,3,4 months of age|BIOLOGICAL: Three doses of experimental sIPV of lot 3 at the schedule of 2,3,4 months of age|BIOLOGICAL: Three doses control wIPV at the schedule of 2,3,4 months of age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Online Cognitive Behavioural Therapy for Addiction: Efficacy and Cost-Effectiveness in a Pragmatic Clinical Trial
Status: COMPLETED
Conditions: Substance Dependence
Interventions: BEHAVIORAL: Computer-based Training for Cognitive Behavioural Therapy|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emotion Management Skill Strengthening in Chronically Ill Patients, Benefiting From Creative and Physical Activities
Status: COMPLETED
Conditions: Emotion Management Skill|Educational Therapy|Creative and Physical Activities
Interventions: BEHAVIORAL: patients choose one creative activity and one physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Environmental And Sensory Experience (EASE) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetic Autonomic Neuropathy
Interventions: DRUG: ORAL ANTIOXIDANT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1
Status: COMPLETED
Conditions: Abnormal Glucose Tolerance|Type 1 Diabetes
Interventions: DRUG: CTLA4-Ig (Abatacept)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mulligan Traction Straight Leg Raise Versus Post Isometric Relaxation on Hamstring Tightness in Asymptomatic Patients
Status: COMPLETED
Conditions: Hamstring Tightness
Interventions: OTHER: Mulligan Traction Straight Leg Raise (TSLR)|OTHER: Post Isometric Relaxation technique (PIR):
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tonabersat in the Prophylaxis of Migraine With Aura
Status: COMPLETED
Conditions: Migraine With Aura
Interventions: DRUG: Tonabersat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome|Acute Respiratory Distress Syndrome|High Frequency Oscillatory Ventilation
Interventions: DEVICE: Selective HFOV|DEVICE: CMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Effectiveness of a Proprietary Probiotic Blend on Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Proprietary Probiotic Blend|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Comparison of FLT to FDG PET/CT in the Early Assessment of Chemotherapy Response in Stage IB-IIIA Resectable NSCLC
Status: COMPLETED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|PROCEDURE: CT|DRUG: Docetaxel|DRUG: FDG|DRUG: FLT|PROCEDURE: PET/CT|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tu Salud Si Cuenta Worksite: Pilot Intervention Study
Status: COMPLETED
Conditions: Obesity|Physical Activity|Diet|Stress
Interventions: BEHAVIORAL: Tu Salud Si Cuenta Worksite Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery
Status: UNKNOWN
Conditions: Pelvic Floor Muscle Electrophysiologic Therapy|Fast-Track Surgery
Interventions: DEVICE: Electrophysiologic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|ARDS
Interventions: DRUG: Placebo|DRUG: Fostamatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Botulinum Toxin Type A in Patients With Overactive Bladder (OAB)
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DRUG: Botulinum Toxin Type A for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Neuropathy|Neurotoxicity Syndrome|Pain|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: DRUG: Carboplatin|DRUG: Glutathione|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Placebo|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2086 in Healthy Adult and Elderly Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: E2086|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery
Status: COMPLETED
Conditions: Adult Diffuse Astrocytoma|Adult Mixed Glioma|Adult Oligodendroglioma|Cognitive/Functional Effects|Neurotoxicity|Psychosocial Effects of Cancer and Its Treatment|Seizure
Interventions: PROCEDURE: cognitive assessment|PROCEDURE: magnetic resonance imaging|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone
Status: RECRUITING
Conditions: Joint Infection
Interventions: OTHER: No-Rinse Solution (NS)|OTHER: Saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tobacco Cessation Treatment Preferences Among Veteran Smokers
Status: COMPLETED
Conditions: Tobacco Use
Interventions: BEHAVIORAL: Personalized Smoking Cessation Facilitation Meetings|DRUG: Personalized Smoking Cessation Pharmacotherapy|BEHAVIORAL: Personalized Text Messaging Support|BEHAVIORAL: SmokefreeVET|BEHAVIORAL: VA Quitline|OTHER: Education about pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Treatment of Mild-Stage Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Memory Disorders|Dementia
Interventions: BEHAVIORAL: Participation in a monitored exercise program|BEHAVIORAL: Personalized aerobic and strength training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calculus Bovis Sativus (CBS) for Ischemic Cerebral Vascular Disease (CBSinICVD)
Status: NOT_YET_RECRUITING
Conditions: Ischemic Cerebrovascular Disease|Acute Ischemic Stroke|Cerebral Small Vessel Diseases
Interventions: DRUG: Calculus bovis sativus (CBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Stimulus Parameters in Flicker Electroretinogram (ERG)
Status: UNKNOWN
Conditions: Retinopathy
Interventions: DEVICE: RETeval color flicker ERG|DEVICE: RETeval dilated versus un-dilated flicker ERG|OTHER: pupil dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Education Program on Evidence-based Practices on Nurses' Competencies and Clinical Decision-Making Levels
Status: NOT_YET_RECRUITING
Conditions: Evidence Based Practice
Interventions: OTHER: Online Educational Intervention|OTHER: Educational Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of rSIFN-co for Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignancies Including Melanoma, Kidney, Lung, Colorectal, Prostate, Neuroendocrine Tumor
Interventions: BIOLOGICAL: rSIFN-co
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Mediterranean Style Diet in Heart Disease Patients Running a Cardiac Rehabilitation Program
Status: UNKNOWN
Conditions: Acute Myocardial Infarction With ST Elevation
Interventions: BEHAVIORAL: Mediterranean style diet|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic, Robot-assisted Intracerebral Hemorrhage Clot Evacuation
Status: WITHDRAWN
Conditions: Intracerebral Hematoma
Interventions: PROCEDURE: Intracerebral catheter placement|DEVICE: Robot-assisted intracerebral catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: GIVINOSTAT (ITF2357) 50 mg o.d. + MTD Hydroxyurea|DRUG: GIVINOSTAT (ITF2357) 50 mg b.i.d. + MTD Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ATX-01 in Participants With DM1
Status: RECRUITING
Conditions: Myotonic Dystrophy 1
Interventions: DRUG: ATX-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epacadostat and Pembrolizumab Before Surgery in Treating Participants With Stage II-III Esophageal or Gastroesophageal Cancer
Status: WITHDRAWN
Conditions: Esophageal Squamous Cell Carcinoma|Esophageal Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Epacadostat|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|OTHER: Pharmacodynamic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis
Status: RECRUITING
Conditions: Treatment Resistant Hypertension|Chronic Hemodialysis
Interventions: DEVICE: renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALgerian Cholecystectomy Outcomes and Determinants Study (AL-CODS)
Status: NOT_YET_RECRUITING
Conditions: Cholecystectomy|Adults|Gall Stone|Polyps|Pancreatitis Biliary|Gallbladder Dyskinesia|Cholecystitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain
Status: RECRUITING
Conditions: Patellofemoral Pain
Interventions: OTHER: Mobilization with Movement|OTHER: No mobilization with movement and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study
Status: COMPLETED
Conditions: Unconsciousness|Consciousness
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhanced Quality in Primary Care for Elders With Diabetes and Dementia
Status: COMPLETED
Conditions: Diabetes|Dementia|Alzheimer Disease
Interventions: BEHAVIORAL: EQUIPED-ADRD Intervention|BEHAVIORAL: Control (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of AZD6738 and Olaparib Combination Therapy in Relapsed Small Cell Lung Cancer Patients [SUKSES-N2]
Status: COMPLETED
Conditions: SCLC
Interventions: DRUG: AZD6738|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients.
Status: COMPLETED
Conditions: COPD|Chronic Obstructive Pulmonary Disease|Moderate to Very Severe COPD
Interventions: DRUG: Aclidinium Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Refractory or Relapsed B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: dualCAR-NK19/70 cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofreeze® vs. a Placebo on Knee Osteoarthritis Walking Gait Characteristics and Pain
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Biofreeze|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of MMSE (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) in Cognitive Assessment in Geriatric Oncology
Status: COMPLETED
Conditions: Geriatrics|Cancer
Interventions: OTHER: cognitive evaluation by MMS (Mini-Mental State Examination) and MoCA (Montreal Cognitive Assessment) tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of 2 Doses of HRV Vaccine Given Concomitantly or Separately With Routine Vaccinations in Healthy Infants in USA
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: 2-dose oral live attenuated G1P[8] human rotavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects
Status: COMPLETED
Conditions: Pharmacology, Clinical|Healthy
Interventions: DRUG: Pomalidomide|DRUG: Ketoconazole|DRUG: Fluvoxamine|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation.
Status: COMPLETED
Conditions: Constipation|Gastrointestinal Disorder
Interventions: DIETARY_SUPPLEMENT: Probiotic Bifidobacterium 1x1010 cfu|DIETARY_SUPPLEMENT: Probiotic Bifidobacterium 1x109 cfu|OTHER: Placebo powder in capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)
Status: WITHDRAWN
Conditions: High Blood Pressure|Liver Transplant|Renal Function Abnormal
Interventions: DRUG: Amlodipine Besylate|DRUG: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Tai Chi Exercise and Receptive Music Therapy for the Elderly
Status: NOT_YET_RECRUITING
Conditions: Elderly|Exercise|Therapy
Interventions: BEHAVIORAL: Tai Chi Exercise|BEHAVIORAL: Receptive Music Therapy|BEHAVIORAL: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: COgnitive Intervention to Restore Attention Using Nature Environment
Status: COMPLETED
Conditions: Heart Failure|Cognitive Dysfunction
Interventions: OTHER: Nature-VR|OTHER: Urban-VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combine TACE and RFA Versus RFA Monotherapy in Unilobar HCC of 3.1 to 7 cm Patient
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Transcatheter Arterial Chemoembolization|PROCEDURE: Radiofrequency ablation|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture or MBSR for Patients With Fatigue and MS
Status: COMPLETED
Conditions: Fatigue|Multiple Sclerosis
Interventions: OTHER: Usual care + acupuncture|OTHER: usual care+mbsr|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The "Free From Pain Exercise Book" Versus "The Back Book".
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia|Back Pain|Arthritis
Interventions: BEHAVIORAL: "The Free From Pain Exercise Book"|BEHAVIORAL: "The Back Book"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dipsticks and Microscopy to Reduce Antibiotic Use in Women's Urinary Tract Infections: a Pilot Trial (MicUTI)
Status: COMPLETED
Conditions: Cystitis Acute|Antibiotic Resistant Infection|Medication Adherence|Urinary Tract Infection Bacterial|Urinary Tract Infection Lower Acute
Interventions: DIAGNOSTIC_TEST: Point-of-care microscopy and dipstick guided management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Unhealthy Alcohol Drinking and Anesthetic Requirement in Women
Status: COMPLETED
Conditions: General Anesthesia
Interventions: BEHAVIORAL: Alcohol drinking|BEHAVIORAL: Alcohol drinking|BEHAVIORAL: Alcohol drinking|BEHAVIORAL: Alcohol drinking|BEHAVIORAL: Alcohol drinking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: huC242-DM4 Treating Patients With Metastatic Gastric or Gastroesophageal Junction Carcinomas
Status: WITHDRAWN
Conditions: Stomach Neoplasms|Metastatic or Locally Advanced Gastric Cancer|Metastatic or Local Advanced GE Junction Cancer
Interventions: DRUG: huC242-DM4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Protein Oral Nutritional Support With Special Nutrients in Patients With Type 2 Diabetes and Foot Ulcer
Status: TERMINATED
Conditions: Healing Ulcer
Interventions: DIETARY_SUPPLEMENT: Cubitan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability, Safety, and Pharmacodynamics of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets in Healthy Participants
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Dexlansoprazole Delayed Release Orally Disintegrating Tablets|DRUG: Dexlansoprazole Delayed Release Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Dacarbazine and Interferon-Alfa to Treat Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Bevacizumab (Avastin)|DRUG: dacarbazine|DRUG: interferon-alfa-2a (Roferon-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Sirolimus for the Treatment of Pachyonychia Congenita (PC)
Status: COMPLETED
Conditions: Pachyonychia Congenita
Interventions: DRUG: 1% sirolimus cream (TD201 1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Romiplostim With Danazol in Patients With Eltrombopag-resistant Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Romiplostim and danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesity, Sarcopenic, Risk of Falls in Spanish Postmenopausal Women
Status: COMPLETED
Conditions: Fall Due to Loss of Equilibrium
Interventions: OTHER: Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With Cisplatin
Status: COMPLETED
Conditions: Ototoxicity|Unspecified Adult Solid Tumor
Interventions: DRUG: alpha-lipoic acid|BEHAVIORAL: Audiology|BIOLOGICAL: laboratory biomarker analysis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes in Myocardial Perfusion During Chronic Multi Site Biventricular Versus Right Ventricular Apex Pacing in Patients With Normal Left Ventricular Function Undergoing His Bundle Ablation for Drug-refractory Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: HIS buldle ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of High Dose MHAA4549A in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: MHAA4549A|DRUG: MHAA4549A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of a New Sweat Collection Support: Impact on Neonatal Screening and Early Treatment of Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Macroduct® Advanced Model 3710 SYS, Wescor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Onset Time of Thiopental Versus Propofol in the Elderly
Status: COMPLETED
Conditions: Induction of Anaesthesia|Age
Interventions: DRUG: Thiopental|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Steroids, Sleep, and Metabolic Dysfunction in Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)|Obstructive Sleep Apnea|Obesity
Interventions: DRUG: Progesterone|DRUG: testosterone|DRUG: glucocorticoid|DEVICE: continuous positive airway pressure|DRUG: Estrogen|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator
Status: COMPLETED
Conditions: Helicobacter Pylori Infection|Dyspepsia
Interventions: DRUG: RHB-105|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Blood Levels and Effects of MGB-BP-3
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MGB-BP-3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Nerivio active device|DEVICE: Nerivio sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a New Thickened Extensively Hydrolyzed Formula
Status: COMPLETED
Conditions: Protein Allergy|Cow's Milk Protein Hypersensitivity
Interventions: DIETARY_SUPPLEMENT: new extensively hydrolysed formula|DIETARY_SUPPLEMENT: Extensively hydrolysed formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency
Status: COMPLETED
Conditions: Liver Disease
Interventions: BIOLOGICAL: Autologous Expanded CD34+ Haemopoietic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Repair Device (VergenixTM STR) in Patients With Epicondylitis (Tennis Elbow)
Status: COMPLETED
Conditions: Non Ruptured Tendon Injuries|Tendinopathy
Interventions: DEVICE: Tissue Repair Device (VergenixTM STR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplantation of Cultivated Limbal Stem Cells on Amniotic Membrane in Limbal Stem Cell Deficiency (LSD) Patients
Status: COMPLETED
Conditions: Limbal Stem Cell Deficiency
Interventions: PROCEDURE: Cultured limbal stem cells Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Ruxolitinib in Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative Neoplasm
Status: UNKNOWN
Conditions: Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative Disorder
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumor|Platinum-resistant Ovarian Cancer
Interventions: BIOLOGICAL: SON-1010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Topical Liposomal Lidocaine and Oral Sucrose for Treatment of Pain in Newborns Undergoing Venipuncture
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: 24% Sucrose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mucosal Flap Reinforced Colorectal Anastomosis and Trans-Anal Vacuum Drainage: A Feasibility Study
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: colorectal anastomosis reinforcement and trans-anal drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Harvesting Lymph Nodes With Carbon Nanoparticles for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Carbon Nanoparticles|PROCEDURE: Gastrectomy with D2 dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Blood Pressure Management
Status: COMPLETED
Conditions: Blood Pressure|Intraoperative Hypotension|Postoperative Complications
Interventions: PROCEDURE: 24 hour blood pressure measurement, fluids, vasopressors|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperoxia During Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter?
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Pulmonary Hypertension|Interstitial Lung Disease|Chronic Lung Disease
Interventions: OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia
Status: RECRUITING
Conditions: Oxygen Toxicity|Anesthesia; Adverse Effect
Interventions: OTHER: LUS-guided choice of Peep|OTHER: Standard choice of Peep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Chiropractic Care on Behavior, Neurological Function and Quality of Life in ADHD Children - A Pilot Study
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: OTHER: Experimental group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mulligan Mobilization Technique in Older Adults With Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Mulligan Mobilization for Study Group|OTHER: Conventional therapy for Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transperineal Intraprostatic Injection of PRX302 Under Ultrasound Guidance for Management of Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: PRX302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dosage Buprenorphine as a Drug Strategy Withdrawal Assistance of Analgesics Opioid
Status: ACTIVE_NOT_RECRUITING
Conditions: High Dosage Buprenorphine
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OB-002H Gel Administered Vaginally and Rectally in HIV-1 Seronegative Adults
Status: COMPLETED
Conditions: HIV Prevention
Interventions: DRUG: OB-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Patient Education on Reported Bone Pain in Breast Cancer Patients Receiving Chemotherapy and Pegfilgrastim
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: General Education DVD|OTHER: Bone Pain Education DVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT - Does Treating Incompetent Perforators Reduce Recurrence?
Status: UNKNOWN
Conditions: Varicose Veins
Interventions: PROCEDURE: EVLA|PROCEDURE: phlebectomies|PROCEDURE: TRansluminal Occlusion of Perforators (TRLOP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT