pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung
Status: TERMINATED
Conditions: Osteosarcoma|Metastatic Osteosarcoma
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Adenovirus-vectored, Intranasal Pandemic Influenza Vaccine.
Status: COMPLETED
Conditions: Influenza A Subtype H5N1 Infection
Interventions: BIOLOGICAL: Pandemic Influenza Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Management of Seizures Post Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury|Post Traumatic Seizures
Interventions: DRUG: Phenytoin Sodium|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Study of MicroRNA Genomics of Blood Stasis Syndrome and of Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease|Unstable Angina|Blood Stasis Syndrome
Interventions: DRUG: Xuesaitong soft capsule|DRUG: Xuesaitong soft capsule Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Type of Laryngeal Mask : I-Gel & LMA ProSeal
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: Laryngeal mask insertion (LMA ProSeal)|DEVICE: Laryngeal mask insertion (I-Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Rechallenge in Irinotecan-pretreated mCRC, KRAS, NRAS and BRAF Wild-type Treated in 1st Line With Anti-EGFR Therapy (CRICKET).
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: cetuximab|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Dosing Regimens of STOP-AST
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss|Tinnitus|Sensorineural Hearing Loss
Interventions: DRUG: Prednisone tablet|DRUG: Ginkgo Biloba Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis
Status: TERMINATED
Conditions: Prostheses and Implants|Stroke|Valve Heart Disease|Anticoagulants and Bleeding Disorders
Interventions: DRUG: Rivaroxaban 15 mg|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: EMDR 2.0 group protocol|OTHER: Mhgap stress module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Intensive Systolic Blood Pressure Control
Status: UNKNOWN
Conditions: Hypertension|Hyperhomocysteinemia
Interventions: DRUG: Standard BP control|DRUG: Moderate BP control|DRUG: Intensive BP control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study About Group and Phone Follow-Up After a Crisis
Status: RECRUITING
Conditions: Suicide|Crisis; Emotional
Interventions: BEHAVIORAL: THRIVE (Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement)|BEHAVIORAL: Discharge / Safety Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir DF|DRUG: TDF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient With Atopic Dermatitis' Needs for Self-management Support - Flexible Patient Centred Consultations
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: BEHAVIORAL: flexible patient centred consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Effect of Radial Shock Wave, Ultrasound-guided Needle Puncture, and Combination of Both in the Treatment of Calcific Tendinitis of the Shoulder
Status: COMPLETED
Conditions: Calcific Tendinitis of the Shoulder
Interventions: DEVICE: radial extracorporeal shock wave therapy|PROCEDURE: ultrasound-guided needle puncture|PROCEDURE: RSWT and USNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Safety and Efficacy of AzA 15% Foam Twice a Day in Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Azelaic acid|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Temperature Used in Thermal Radiofrequency Ablation
Status: TERMINATED
Conditions: Low Back Pain
Interventions: PROCEDURE: RFA at 90 degrees Celsius|PROCEDURE: RFA at 80 degrees Celsius|DEVICE: C-arm guided 20-gauge radiofrequency needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplant for Patients With Severe Aplastic Anemia
Status: TERMINATED
Conditions: Aplastic Anemia
Interventions: DRUG: Cytoxan|DRUG: Campath|RADIATION: Total Body Irradiation (TBI)|DRUG: FK-506|DRUG: Methotrexate|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis
Status: UNKNOWN
Conditions: Bronchiectasis
Interventions: DRUG: Tobramycin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation for Non-occlusive Portal Vein Thrombosis in Patients With Liver Cirrhosis
Status: WITHDRAWN
Conditions: Liver Cirrhosis|Portal Vein Thrombosis|Anticoagulation
Interventions: DRUG: Nadroparin Calcium and Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Pneumococcal Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Healthy Subjects|Pneumococcal Infections
Interventions: BIOLOGICAL: 13-Valent Pneumococcal Conjugate Vaccine (13vPnC)|BIOLOGICAL: 7-Valent Pneumococcal Conjugate Vaccine (7vPnC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Impact of EPA and DHA Supplementation on Plasma Biomarkers of Inflammation (n3)
Status: COMPLETED
Conditions: Cardiovascular Disease, Inflammation
Interventions: DIETARY_SUPPLEMENT: High DHA|DIETARY_SUPPLEMENT: High EPA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Blood Sugar Lowering Effect and Safety of Two Insulin Treatments in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial)
Status: TERMINATED
Conditions: Hypertension, Pulmonary|Diseases of Mitral Valve
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Povidone Iodine and Cesarean Section Wound Infections
Status: COMPLETED
Conditions: Wound Infections
Interventions: DRUG: Povidone Iodine 10% vand cesarean section wound infections|DRUG: Povidone Iodine 7.5% vand cesarean section wound infections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Stem Cells Therapy for Fecal Incontinence in Children After Posterior Sagittal Ano-rectoplasty
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Stem Cells Injection Technique|PROCEDURE: Stem Cell Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bibliotherapy-based Psychoeducation Program the Effect of Elderly Individuals on Depression and Hopelessness Levels
Status: COMPLETED
Conditions: Elderly People|Depressive Symptoms|Despondency
Interventions: BEHAVIORAL: bibliotherapy-based psychoeducation program|BEHAVIORAL: psychoeducation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Combined VISUDYNE Therapy With Kenalog In CNV Secondary To Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Visudyne|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Laser Iridotomy Versus Surgical Iridectomy in Early Angle Closure
Status: UNKNOWN
Conditions: Intraocular Pressure Changes|Peripheral Anterior Synechiae Increasing
Interventions: PROCEDURE: Surgical Iridectomy|PROCEDURE: Laser Iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Plus Dexamethasone as Maintenance Therapy for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide plus dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Efficacy and Safety of Ayurveda Combination in Patients With Mild-to-Moderate COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Shanshamani Vati Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Hu3F8|DRUG: GM-CSF|DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Complex Decongestive Therapy in Patients With Lymphedema
Status: COMPLETED
Conditions: Lymphedema|Urine Marking|Quality of Life|Edema
Interventions: OTHER: Complex Decongestive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Infusion as Prevention for Graft Rejection and Graft-versus-host Disease
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: PROCEDURE: Mesenchymal stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction
Status: COMPLETED
Conditions: Female Sexual Dysfunction
Interventions: DEVICE: percutaneous tibial nerve stimulation (PTNS)|DEVICE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Incentivizing Buprenorphine-Naloxone Initiation in Emergency Departments
Status: COMPLETED
Conditions: Opioid Use
Interventions: BEHAVIORAL: Training|BEHAVIORAL: Behavioral economic enhanced arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Status: COMPLETED
Conditions: Preeclampsia|Hypotension
Interventions: DRUG: Ephedrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury Cervical
Interventions: DRUG: WJ-MSC (XCEL-UMC-BETA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Estimate the Effect Sizes of HRCT Endpoints in Response to Glucocorticoid Induction Therapy in Subjects With Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Glucocorticoid (prednisone or prednisolone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Brensocatib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polarity Action in Electrical Stimulation Transcutaneous Donors for Treatment Areas Burned Patients
Status: UNKNOWN
Conditions: Burn
Interventions: DEVICE: High voltage|DEVICE: Neuromuscular transcutaneous electrical stimulation (TENS)|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Acute Lymphoblastic Leukemia With Failed Remission|B-cell Lymphoma Refractory|B-cell Lymphoma Recurrent
Interventions: BIOLOGICAL: KQ-2002 CAR-T cells （CD19/CD22 CAR T-Cells）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Mild Cognitive Impairment
Interventions: DRUG: Henagliflozin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HTD1801 in Healthy Subjects
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: HTD1801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Grape Seed Extract in Asymptomatic Non-Metastatic Prostate Cancer Patients With Rising PSA
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Grape Seed Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight|Overweight or Obesity
Interventions: DRUG: Orforglipron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of First Line B-RI for Treatment Naive Waldenström's Macroglobulinemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Ibrutinib / Bortezomib / Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: CT-Guided Genicular Nerve Ablation|PROCEDURE: Fluoroscopic-Guided Genicular Nerve Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Advanced Chronic Myeloid Leukemia|Philadelphia Chromosome-Positive Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: Listaftoclax|DRUG: Olverembatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aplidin (Plitidepsin) 3 h iv in Subjects With Relapsing or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Plitidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Immunity/Physical Performance
Status: UNKNOWN
Conditions: Vitamin D Status
Interventions: DIETARY_SUPPLEMENT: Oral Vitamin D3|DIETARY_SUPPLEMENT: Placebo Oral Vitamin D3|RADIATION: Solar simulated radiation (SSR)|RADIATION: Placebo SSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Aerobic Exercise, Resistance Exercise, or Flexibility and Relaxation Training in Inactive Older Female Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Cancer Survivor|Fatigue|Long-term Effects Secondary to Cancer Therapy in Adults|Psychosocial Effects of Cancer and Its Treatment
Interventions: BEHAVIORAL: exercise intervention|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: survey administration|PROCEDURE: assessment of therapy complications|PROCEDURE: fatigue assessment and management|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Long-Term Safety of Crisaborole Ointment, 2% in Japanese Pediatric and Adult Participants With Mild to Moderate Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Fractional Ablative CO2 Laser vs Control on Acute Traumatic Injuries to Prevent Scar Formation
Status: COMPLETED
Conditions: Scar|Trauma Injury|Burns|Wound Heal|Early Medical Intervention|Laser Therapy
Interventions: DEVICE: Fractional ablative CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROMPT - Palifermin in Reduction of Oral Mucositis in PBSC Transplantation
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Multiple Myeloma
Interventions: DRUG: Kepivance (Palifermin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of PEGIFNα1b in Chinese Healthy Adults
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: DRUG: PEGIFNα1b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Assessment in Patients Undergoing Prolonged Suppressive Antibiotherapy for Prosthetic Joint Infection.
Status: RECRUITING
Conditions: Prosthetic Joint Infection
Interventions: OTHER: Quality of life questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proof-of-Concept Study of a Single Application of an Investigational Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes
Status: TERMINATED
Conditions: Acute Otitis Media
Interventions: DRUG: AL-60371/AL-817 otic suspension|DRUG: Ciprofloxacin 0.3%/dexamethasone 0.1% otic suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%
Status: COMPLETED
Conditions: Chronic Blepharitis
Interventions: DRUG: Ivermectin 0.1% Metronidazole 1%|OTHER: None intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Azathioprine in Recurrent Implantation Failure
Status: COMPLETED
Conditions: Recurrent Implantation Failure|In Vitro Fertilization|Intracytoplsmic Sperm Injection
Interventions: DRUG: Azathioprine Pill|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Relapse Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observer-blind, Cohort Randomized, Exploratory Phase 3 Study to Evaluate the Safety and Immunogenicity of Recombinant Covid-19 Vaccine, mRNA Covid-19 Vaccine and Recombinant SARS-CoV-2 Trimeric S-protein Subunit Vaccine as 4th Dose in Individuals Primed/ Boosted With Various Regimens
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: AstraZeneca/Fiocruz|BIOLOGICAL: Pfizer/Wyeth|BIOLOGICAL: Clover SCB-2019
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy
Status: UNKNOWN
Conditions: Melanoma, Malignant, of Soft Parts
Interventions: DRUG: Vemurafenib and Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Open Label Extension Study of BIBF 1120 Administered Orally Once or Twice Daily to Establish Safety, Pharmacokinetics and Efficacy in Patients With Advanced Solid Tumours and Clinical Benefit From Previous Therapy With BIBF 1120
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Venetoclax to Augment Epigenetic Modification and Chemotherapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: Venetoclax|DRUG: Azacitadine|DRUG: Vorinostat|DRUG: Cytarabine|DRUG: Fludarabine|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COUREUR Study Myocardial Inflammation in Cyclist Part 2
Status: COMPLETED
Conditions: Myocardial Inflammation
Interventions: DIAGNOSTIC_TEST: cardiac MRI|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: RootiRx for the ECG monitoring during the cycling ride|DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dendritic Cell (DC)-Based Vaccines Loaded With Allogeneic Prostate Cell Lines in Combination With Androgen Ablation in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Cancer of Prostate|Cancer of the Prostate|Neoplasms, Prostate|Neoplasms, Prostatic|Prostate Cancer|Prostate Neoplasms|Prostatic Cancer
Interventions: BIOLOGICAL: androgen ablation (AA)|BIOLOGICAL: DC1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Toripalimab|OTHER: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PF-05175157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of n-3 Polyunsaturated Fatty Acids in a Protein-enriched Diet With Low GI in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Overweight|Obese|Insulin Resistance|Diabetes
Interventions: DIETARY_SUPPLEMENT: n-3 PUFA in protein-enriched low-GI diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hydrolysed Rice Formula Study
Status: RECRUITING
Conditions: Cow's Milk Protein Allergy
Interventions: OTHER: Hydrolysed Rice Protein Formula|OTHER: Cow's Milk Based Extensively Hydrolysed Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical, Neurophysiological and Neuroendocrine Effects of Aerobe Exercise in Generalized Anxiety Disorder (GAD)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder (GAD)
Interventions: OTHER: high-intensive aerobe exercise|OTHER: low-intensive aerobe exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Video-Based Mindful Movement Intervention Prior to Pelvic Exams
Status: COMPLETED
Conditions: Anxiety State|Pain|Depression
Interventions: BEHAVIORAL: 5-Minute Mindful Movement Video|BEHAVIORAL: Written Educative Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BOTOX® Treatment for Adults With a Wide Lower Face Due to Masseter Muscle Prominence
Status: COMPLETED
Conditions: Masseter Muscle Prominence
Interventions: BIOLOGICAL: Botulinum Toxin Type A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Meditation for the Treatment of Women With Comorbid PTSD and SUD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Substance-Related Disorders
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention (MBRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate
Status: TERMINATED
Conditions: Pleural Mesothelioma|Malignant Pleural Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Sodium Thiosulfate|DRUG: ALIMTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Glass Ionomer With Advanced Glass Hybrid Technology Versus Resin Modified Glass Ionomer in Adult Patients With Carious Cervical Lesions After One Year
Status: NOT_YET_RECRUITING
Conditions: Dental Caries Class v
Interventions: DRUG: Glass Ionomer with Advanced Glass Hybrid Technology (Equia forte HT fil, GC, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FOLFIRI + Panitumumab Using Ultra-selection Technology of Patients With Stage IV Colorectal Cancer Refractory to Irinotecan Without Any Mutation on KRAS, PIK3Ca, BRAF and NRAS Genes Detected With Highly Sensitive Techniques
Status: COMPLETED
Conditions: Stage IV Colorectal Cancer
Interventions: DRUG: panitumumab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidiolex (CBD) in Patients With Biochemically Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Recurrent|Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: Epidiolex Oral Liquid Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
Status: COMPLETED
Conditions: Acne|Atrophic Scar
Interventions: DEVICE: a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece|DEVICE: a ablative fractional 2940-nm Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC
Status: RECRUITING
Conditions: Metastatic Microsatellite-stable Colorectal Cancer
Interventions: DRUG: Experimental drug|DRUG: Control Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns
Status: COMPLETED
Conditions: Preterm Birth|Premature|Bronchopulmonary Dysplasia|Respiratory Distress Syndrome|Mechanical Ventilation Complication|Mechanical Ventilation Pressure High|Oxygen Toxicity|Neonatal Respiratory Failure|Atelectasis Neonatal|Pneumonia Neonatal|Lobar Collapse|Chronic Liver Disease|Hyaline Membrane Disease
Interventions: OTHER: chest physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trunk Extensor Endurance Training Versus Scapular Mobilization in Patient With Thoracic Kyphosis
Status: RECRUITING
Conditions: Thoracic Kyphosis
Interventions: OTHER: Trunk Extensor Endurance training & Scapular mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Vinflunine Plus Capecitabine in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Vinflunine plus Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calistar A vs. Calistar S - Comparative Cohort Retrospective Analysis of Single Incision POP Systems
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Calistar A mesh to treat anterior and apical POP|DEVICE: Calistar S mesh to treat anterior and apical POP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate Hypercholesterolemia
Status: COMPLETED
Conditions: Moderate Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Probiotics bacterial strains|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Response Modifier (Arabinoxylan Rice Bran/MGN-3/Biobran) With Interferon-Alpha for HCV
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: pegylated IFN|DIETARY_SUPPLEMENT: Biobran|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Early Administration of the Lutein/Zeaxanthin in Premature Newborns
Status: WITHDRAWN
Conditions: Antioxidant Role of the Lutein in Preterm Newborn
Interventions: DIETARY_SUPPLEMENT: LUTEIN ofta 0,5 gocce|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of Abiraterone Acetate and Prednisone in Participants With Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Prostatic Neoplasms|Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
Status: UNKNOWN
Conditions: Angina, Unstable|Non-ST-Segment Elevation Myocardial Infarction
Interventions: DEVICE: OCT|DEVICE: eLuting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diet and Physical Activity Change or Usual Care in Improving Progression-Free Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Malignant Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7|Undifferentiated Fallopian Tube Carcinoma|Undifferentiated Ovarian Carcinoma
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|BEHAVIORAL: Compliance Monitoring|OTHER: Counseling|OTHER: Educational Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)
Status: UNKNOWN
Conditions: Parkinson Disease|Neurodegenerative Diseases|Movement Disorders|Central Nervous System Diseases|Brain Diseases|Basal Ganglia Diseases|Parkinsonian Disorders
Interventions: BEHAVIORAL: Participant self-assessment surveys|BEHAVIORAL: Phonation|BEHAVIORAL: Gait and balance|BEHAVIORAL: Memory|BEHAVIORAL: Dexterity|BEHAVIORAL: Participant open-response writing|OTHER: Parkinson mPower mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trazodone vs. Quetiapine for the Treatment of ICU Delirium
Status: RECRUITING
Conditions: Delirium|Delirium of Mixed Origin|Delirium, Sepsis Associated|Delirium in Old Age|Delirium Confusional State|Psych|Morality|Treatment Side Effects
Interventions: DRUG: Trazodone|DRUG: Quetiapine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mini-autogenous Skin Grafts With Skin Homografts Versus Autogenous Skin Graft for Covering Post Burn Wounds in Children
Status: COMPLETED
Conditions: Burns
Interventions: PROCEDURE: Mini autogenous skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ericksonian Hypnosis in the Management of Chronic Pain Related to Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Chronic Pain
Interventions: BEHAVIORAL: Erickson hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Slowly Digestible Carbohydrates on the Gut-brain Axis
Status: COMPLETED
Conditions: Appetitive Behavior|Obesity|Diabetes Mellitus, Type 2
Interventions: OTHER: Rice flour|OTHER: Alternanoligosaccharide 15|OTHER: Inulin|OTHER: Waxy potato starch|OTHER: Waxy potato starch + epigallocatechin gallate (EGCG)|OTHER: Chickpea flour + epigallocatechin gallate (EGCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Suicide Prevention and Intervention in Spain: the SURVIVE Study
Status: UNKNOWN
Conditions: Suicide|Suicide, Attempted|Depression
Interventions: BEHAVIORAL: Telephone-based management|BEHAVIORAL: iFightDepression for Suicide|BEHAVIORAL: Treatment as Usual|BEHAVIORAL: Self Awareness of Mental Health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iKinnect2.0 for Juvenile Justice Involved Youth at Risk for Suicide
Status: RECRUITING
Conditions: Child Behavior Disorders|Suicide and Self-harm
Interventions: DEVICE: iKinnect2.0|DEVICE: Active Control App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of TENS in Pain During Application of Carboxytherapy in Patients With Gynoid Lipodystrophy
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Neurodyn Portable activeTENS, IBRAMED®|DEVICE: Neurodyn Portable placeboTENS, IBRAMED®|DEVICE: Carboxyderm S20-1C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Types of Exercise on Cognitive Function in Postmenopausal Hypertensive Women
Status: RECRUITING
Conditions: Cognitive Function|Hypertension
Interventions: BEHAVIORAL: Walking exercise + resistance training|BEHAVIORAL: Resistance training|BEHAVIORAL: Walking exercise|BEHAVIORAL: Health promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough
Status: TERMINATED
Conditions: Cough
Interventions: DRUG: GSK2798745|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone|DRUG: Olanzapine (enrollment closed in this treatment)|DRUG: Molindone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Clinical Activity of ASM-024 in Subjects With Mild Allergic Asthma
Status: COMPLETED
Conditions: Mild Allergic Asthma
Interventions: DRUG: ASM-024|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Balance in Patients With Pes Planus
Status: UNKNOWN
Conditions: Pes Planus|Fall Risk
Interventions: DIAGNOSTIC_TEST: Inky foot analysis|DIAGNOSTIC_TEST: Evaluation of plantar pressure with pedobarography|DIAGNOSTIC_TEST: Balance assessment with computerized posturography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Using NaviAid™ BGE Device (Balloon Guided Endoscopy) For Endoscopic Diagnosis and Treatment
Status: COMPLETED
Conditions: Intestinal Diseases
Interventions: DEVICE: NaviAid™ BGE Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in Combination With Bortezomib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: Mantle-Cell Lymphoma
Interventions: DRUG: Obatoclax mesylate|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Voriconazole on the Pharmacokinetics and Pharmacodynamics of Oral Buprenorphine: A Two-phase Cross-over Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Vorikonazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Safety and Effects of Autologous Adipose-Derived SVF Cells in Patients With Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Harvesting and Implantation of Adipose-Derived Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation in aGvHD After ASCT
Status: RECRUITING
Conditions: Graft Versus Host Disease in GI Tract
Interventions: BIOLOGICAL: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Growth Hormone Releasing Hormone (GHRH)|DRUG: Placebo Growth Hormone Releasing Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Direct Current Stimulation (tDCS) in Addition to Tinnitus Retraining Therapy (TRT) for Treatment of Chronic Tinnitus Patients
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Furcation Defects
Interventions: PROCEDURE: Access flap & surgical debridement|PROCEDURE: Application of bone substitute material (BioOss Collagen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of a Tacrolimus Based Immunosuppressive Regimen in Stable Kidney Transplant Recipients Converted From Cyclosporine Based Immunosuppressive Regimen
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT