pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Influence of Carbohydrate on Amino Acid Absorption From Dietary Protein (ICADP)
Status: COMPLETED
Conditions: Muscle Protein Synthesis|Amino Acid
Interventions: DIETARY_SUPPLEMENT: Meat Hydrolysate|DIETARY_SUPPLEMENT: Cluster Dextrin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA
Status: COMPLETED
Conditions: Laryngeal Neoplasms|Hypopharyngeal Neoplasms
Interventions: DRUG: Weekly Carboplatin & Taxol w/concurrent RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Stress Reduction Intervention Study
Status: UNKNOWN
Conditions: Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Cognitive-Behavioral Therapy (CBT) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSAO in Treating Patients With Advanced Solid Tumors That Have Not Responded to Therapy
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: angiogenesis inhibitor GSAO|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ECG Optimization of CRT: Evaluation of Mid-term Response
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Device programming: nominal|OTHER: Programming optimization by QRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose-escalation Study of FluBHPVE6E7 in HPV16-infected Women
Status: RECRUITING
Conditions: HPV Infection|HPV-Related Cervical Carcinoma
Interventions: BIOLOGICAL: FluBHPVE6E7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: VTX-2337|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: 5-fluorouracil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of the Safety and Efficacy of Atiprimod Treatment in Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Atiprimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perceptual Abnormalities and Their Malleability in BDD
Status: RECRUITING
Conditions: Body Dysmorphic Disorder
Interventions: BEHAVIORAL: attentional modulation|OTHER: perceptual modulation|OTHER: naturalistic viewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CEUS for Blunt Abdominal Trauma in Children
Status: RECRUITING
Conditions: Trauma Abdomen
Interventions: DRUG: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON]|DEVICE: contrast-enhanced ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BAY63-2521 - Long-term Extension Study in Patients With Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin A Compound in Treating Participants With Resectable Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Stage I Lung Cancer|Stage Ib Lung Carcinoma|Stage IA Lung Carcinoma AJCC V7|Stage IIA Lung Carcinoma|Stage IIIA Lung Carcinoma
Interventions: DRUG: Vitamin A Compound|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specific Screw Holes Locating Surgical Guide and Pre-bent Plates
Status: UNKNOWN
Conditions: Mandibular Fractures
Interventions: DEVICE: specific screw holes locating surgical guide and pre-bent plates|DEVICE: classical reduction and internal fixation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nivolumab and Yttrium Y 90 Glass Microspheres in Treating Patients With Advanced Liver Cancer
Status: COMPLETED
Conditions: Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|RADIATION: Yttrium Y 90 Glass Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Safety and Efficacy of NTCELL® [Immunoprotected (Alginate-Encapsulated) Porcine Choroid Plexus Cells for Xenotransplantation] in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: NTCELL Implantation|OTHER: Sham Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Single Incision Versus Four Ports Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Single Incision Laparoscopic Cholecystectomy (SILC)|PROCEDURE: Four Ports Laparoscopic Cholecystectomy (4PLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web-based Training on Gaining Exercise Behavior in Coronary Artery Patients
Status: UNKNOWN
Conditions: Decision Making|Exercise|Self Efficacy
Interventions: BEHAVIORAL: Web-based exercise training based on the transtheoretic model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery
Status: UNKNOWN
Conditions: Delirium|Inflammation|Cognitive Disorders|Amnestic|Dementia
Interventions: DRUG: Ketamine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Diet in Patients With Senile Dementia
Status: UNKNOWN
Conditions: Alzheimer's Disease|Parkinson's Disease|Senile Dementia
Interventions: DIETARY_SUPPLEMENT: Supressi. T-Diet plus Range|DIETARY_SUPPLEMENT: High Protein. T-Diet plus Range
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine
Status: COMPLETED
Conditions: Closed Multiple Fractures of Upper and Lower Limbs
Interventions: DRUG: Ketamine-midazolam|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Corpus Luteum Presence or Absence in the Incidence of Preeclampsia After Frozen Embryo Transfer
Status: TERMINATED
Conditions: Pre-Eclampsia|Frozen Embryo Transfer
Interventions: PROCEDURE: FROZEN EMBRYO TRANSFER IN SUBSTITUTED CYCLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Proton Pump Inhibitors in Cirrhotic Patients With Acute Variceal Bleeding
Status: NOT_YET_RECRUITING
Conditions: Upper Gastrointestinal Hemorrhage
Interventions: DRUG: Proton Pump Inhibitors|DRUG: No Proton Pump Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer
Status: COMPLETED
Conditions: Chronic Ulcer|Healing Ulcer
Interventions: BIOLOGICAL: gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration|BIOLOGICAL: Collagenase ointment|BIOLOGICAL: Gel with 10% peel powder of unripe banana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Schizophrenic Patients in Integrated Care
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Quetiapine XR|OTHER: Integrated Care Program (ICP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation and Stress Reduction Training for Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: BEHAVIORAL: Stress Reduction Training A|DEVICE: active tVNS|BEHAVIORAL: Stress Reduction Training B|DEVICE: sham tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Boceprevir in HIV-HCV Coinfected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin
Status: COMPLETED
Conditions: HCV Coinfection|HIV-1 Infection
Interventions: DRUG: Boceprevir, Peg-interferon alfa 2b and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of MGCD0103 Given Three-Times Weekly In Patients With Leukemia Or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: MGCD0103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Therapy With Ursodiol to Reduce the Incidence of Gallstones Formation in Patients After Bariatric Surgery
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DRUG: URSODIOL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DPP4|DRUG: GLP-1 receptor agonist|DRUG: Basal Insulin|DRUG: SLGT2|DRUG: SU
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Feeding Strategies for Hypoplastic Left Heart Syndrome Infants
Status: COMPLETED
Conditions: Hypoplastic Left Heart Syndrome|Growth Failure
Interventions: OTHER: Continuous Feeding Regimen|OTHER: Intermittent Bolus Feeding Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, Efficacy and Immunogenicity of an Influenza A Vaccine (FP-01.1) in Healthy Volunteers Following Virus Challenge
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: Vaccine FP-01.1|DRUG: Placebo|OTHER: Virus Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Intervention to Reduce Metabolic Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia|Intestinal Microbiota|Dietary Habits|Clinical Trial|Obesity
Interventions: BEHAVIORAL: AIA-D|BEHAVIORAL: CONV-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative New-onset Atrial Fibrillation in Cardiac Surgery: DECS-PNAF Project
Status: COMPLETED
Conditions: Atrial Fibrillation|Cardiac Surgery
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Disorder Related to Bone Marrow Transplantation
Interventions: DRUG: Fludarabine|DRUG: Melphalan|PROCEDURE: Allogeneic Transplant|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Dystonia
Interventions: DEVICE: TUS Active|DEVICE: TUS Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrahepatic Delivery of SD-101 by Pressure-Enabled Regional Immuno-oncology (PERIO), With Checkpoint Blockade in Adults With Metastatic Uveal Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Uveal Melanoma in the Liver
Interventions: DRUG: SD-101|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab and Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma
Status: UNKNOWN
Conditions: Liposarcoma|Soft Tissue Sarcoma
Interventions: DRUG: ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Smartphone Based Intervention for the Prevention of Relapse in Alcohol Dependence
Status: UNKNOWN
Conditions: Alcohol Dependence|Alcohol Abuse|Alcohol Use Disorder
Interventions: BEHAVIORAL: Anti Alcohol App with Active Cognitive Bias|BEHAVIORAL: Inactive Cognitive Bias Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Usability of Virtual Reality in Subjects With Mild Cognitive Impairment or Alzheimer's Disease
Status: COMPLETED
Conditions: MCI|Alzheimer's Disease
Interventions: OTHER: Condition virtual reality (VR) then Condition classic cognitive stimulation (CCS)|OTHER: Condition classic cognitive stimulation (CCS) then Condition virtual reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Mosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Autologous Stem Cell Transplant-Eligible Patients With Relapsed/Refractory Aggressive B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Transformed B-Cell Lymphoma|Follicular Lymphoma Grade 3B
Interventions: DRUG: Mosunetuzumab|DRUG: DHAX|DRUG: ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flexible Ureteroscopy With and Without Ureteral Access Sheath in Treatment of Large Renal Stones
Status: COMPLETED
Conditions: Flexible Ureteroscopy|Ureteral Access Sheath|Large Renal Stones
Interventions: PROCEDURE: Flexible ureteroscope with ureteral access sheath|PROCEDURE: Flexible ureteroscope without ureteral access sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCT for Older Diabetic Adults
Status: COMPLETED
Conditions: Diabetes|Older Diabetic Persons Without Dementia
Interventions: BEHAVIORAL: Individualized and adaptive computerized cognitive training|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Supplementation of Lactogyn in Women With Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DIETARY_SUPPLEMENT: Lactogyn|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Descending Aorta Blood Flow to Guide Fluid Therapy During Surgery
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DIAGNOSTIC_TEST: Measurement of blood flow in descending aorta by suprasternal ultrasound Doppler technique|DIAGNOSTIC_TEST: Measurement of blood flow in descending aorta by transoesophageal ultrasound Doppler technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Sulfasalazine on BOLD Response to Alcohol Cues
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Sulfasalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Sequence Intubation With Rocuronium in Elderly Patients
Status: UNKNOWN
Conditions: Rapid Sequence Induction|Rapid Sequence Intubation|Rocuronium
Interventions: DEVICE: Train of four(TOF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Chitosan-N-Acetylcysteine on IOL-power Prior to Cataract Surgery
Status: TERMINATED
Conditions: Eye Diseases
Interventions: DEVICE: Lacrimera|DEVICE: Hylo-Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DEVICE: LifePort® perfusion machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a Short Course of Gamma Tocopherol Supplementation in Adult Subjects
Status: COMPLETED
Conditions: Gamma Tocopherol Serum Levels
Interventions: DIETARY_SUPPLEMENT: Gamma tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: GS+Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Hyperstimulation Syndrome|Infertility, Female
Interventions: DRUG: Pregnyl (1,500) IU|DRUG: 1.5 mL of normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manta Study: Avastin Versus Lucentis in Age Related Macular Degeneration
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antithrombotic Treatment After IntraCerebral Haemorrhage
Status: RECRUITING
Conditions: Cerebral Hemorrhage|Intracranial Hemorrhages|Atrial Fibrillation|Anticoagulant-Induced Bleeding|Secondary Prevention
Interventions: DRUG: Antithrombotic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate the Effect of Rosiglitazone and Ramipril on Pre-clinical Vasculopathy in Diabetes and IGT Patients
Status: COMPLETED
Conditions: Diabetes|Impaired Glucose Tolerance
Interventions: DRUG: Rosiglitazone|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection|Pyelonephritis
Interventions: DRUG: CXA-201|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Resveratrol in Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Resveratrol Pill|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statin InTensity to Prevent Coronary Artery Vasculopathy After Heart Transplantation
Status: NOT_YET_RECRUITING
Conditions: Vasculopathy
Interventions: DRUG: Atorvastatin 80 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pediatric Schizophrenia Efficacy and Safety Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone 40 mg|DRUG: Lurasidone 80 mg|DRUG: Placebo 40 or 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Dyskinesia|Parkinson's Disease
Interventions: DRUG: AVP-923-45|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isatuximab, Pomalidomide, Elotuzumab and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab (for run-in portion)|DRUG: Isatuximab (for expansion)|DRUG: Pomalidomide|DRUG: Elotuzumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 'Mindfulness-Based Joyful Sleep' Intervention in Young and Middle-aged Individuals With Insomnia
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: Mindfulness-Based Joyful Sleep|BEHAVIORAL: CBT-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kenya HIV Self-Testing in PrEP Delivery
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: COMBINATION_PRODUCT: 6-month PrEP + blood-based HIV self-test|COMBINATION_PRODUCT: 6-month PrEP + oral fluid HIV self-test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Experimental and Clinical Investigation of the Implant Surface Roughness Reduction Effect on Early-stage Fibrosis
Status: COMPLETED
Conditions: Capsular Contracture Associated With Implant|Foreign-Body Reaction|Wounds and Injuries|Tissue Expander Disorder
Interventions: OTHER: Patient Satisfaction Questionnaire|DIAGNOSTIC_TEST: Pregnancy test|PROCEDURE: Blood draw|PROCEDURE: Expander based breast reconstruction|PROCEDURE: Ultrasound of breast|OTHER: S(AE )monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of a Nasal Allergen Challenge Procedure Using Dust Mite Extract
Status: WITHDRAWN
Conditions: Dermatophagoides Farinae Allergy|Asthma|Healthy
Interventions: BIOLOGICAL: dust mite inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Real-world Effectiveness With Palbociclib Plus Endocrine Therapy as First-line/Second-line Treatment for HR+/HER2- Advanced Breast Cancer in Japan
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Endocrine therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Review of Human Herpes Viruses in Burns
Status: COMPLETED
Conditions: Human Herpes Virus|Herpes Simplex Virus|Varicella-zoster Virus|Chickenpox|Cytomegalovirus|Burns
Interventions: OTHER: Review of the Literature for Human Herpes Virus infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Abatacept s.c. for aGVHD Prevention in Haplo-HCT
Status: RECRUITING
Conditions: Abatacept|Acute-graft-versus-host Disease|Haplo-identical HCT|Prevention
Interventions: DRUG: Abatacept s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preventing Overdose Using Information and Data From the Environment
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Overdose|Drug Overdose
Interventions: BEHAVIORAL: PROVIDENT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PAC-14028 cream 0.1%|DRUG: PAC-14028 cream 0.3%|DRUG: PAC-14028 cream 1.0%|DRUG: PAC-14028 cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of IV ACHN-490 Injection on the QT/QTc Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Cardiac Effects in Normal Healthy Volunteers
Interventions: DRUG: ACHN-490 Injection|DRUG: ACHN-490 Injection|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 177Lu-Dotatate PRRT in Metastatic GEP-NEN Patients
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-Dotatate PRRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Unintentional Leakage When Using Nasal CPAP - Study B
Status: NOT_YET_RECRUITING
Conditions: Continuous Positive Airway Pressure|Adverse Effect|Obstructive Sleep Apnea
Interventions: DEVICE: Oronasal CPAP|DEVICE: Nasal CPAP plus Chinstrap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supplements and Social Skills Intervention Study
Status: COMPLETED
Conditions: Conduct Disorder|Attention Deficit Hyperactivity Disorder|Oppositional Defiant Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3|BEHAVIORAL: Social Skills Training|OTHER: Standard Treatment (or TAU in Child Guidance Clinic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Helium-3 and Xenon-129 Magnetic Resonance Imaging
Status: RECRUITING
Conditions: COPD|Bronchiectasis
Interventions: OTHER: Hyperpolarized Helium MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Steroids on Post-tonsillectomy Morbidities
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting
Interventions: DRUG: IV dexamethasone|DRUG: Oral prednisolone|DRUG: Paracetamol|DRUG: IV saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Foot Massage Applied Before a Bronchoscopy Procedure on Physiological Parameters and Anxiety
Status: COMPLETED
Conditions: Physiological Parameters|Anxiety|Bronchoscopy
Interventions: OTHER: Foot massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use
Status: WITHDRAWN
Conditions: Opioid Use Disorder
Interventions: DRUG: Placebo|DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mild Ankle Sprain Treatment: Functional Bandaging vs. no Immobilization
Status: RECRUITING
Conditions: Primary Disease or Condition Being Studied in the Trial or the Focus of the Study Mild Ankle Sprain
Interventions: OTHER: Control|PROCEDURE: Functional bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis
Status: COMPLETED
Conditions: Nasal Polyposis
Interventions: BIOLOGICAL: Benralizumab 30 mg SC + Mometasone Furoate|BIOLOGICAL: Matching placebo SC + Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depression
Interventions: BEHAVIORAL: Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Platelet Reactivity in PAD Undergoing Percutaneous Angioplasty
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Critical Limb Ischemia|Claudication, Intermittent
Interventions: DRUG: Aspirin 300mg and Clopidogrel 300mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness Mediation Intervention in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Mindfulness meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: tenecteplase|DRUG: alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics
Status: RECRUITING
Conditions: Osteomyelitis|Diabetes|Amputation
Interventions: DRUG: Rifampin|DRUG: Riboflavin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Ultrasound Remission a Real Remission? Does Ultrasound Permit to Achieve and Maintain the Remission in Rheumatoid Arthritis Patients More Efficiently Than Clinical Scores?
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Remission
Interventions: DEVICE: US power doppler|OTHER: Usual care|OTHER: ACR/EULAR criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Hypothermia in Patients Submitted to Transurethral Resection
Status: COMPLETED
Conditions: Hypothermia; Anesthesia|Peroperative Complication
Interventions: DEVICE: WarmTouch Model 5900, Covidien Ltd, Mansfield, USA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of a Knitting Program on Osteoarthritis Symptoms in Elderly Women
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Knitting and education (pamphlet)|OTHER: Education (pamphlet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Impact of Used Probiotic Strains and Diet on Body Composition, Cardiopulmonary Efficiency and the Incidence of Gastrointestinal Disorders in Runners
Status: COMPLETED
Conditions: Gastrointestinal Disorder, Functional
Interventions: DIETARY_SUPPLEMENT: SANPROBI BARRIER|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Genetic Expression and Prediction of Response to Neoadjuvant Docetaxel or Doxorubicin in Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Short Nap During the Night Shift of Healthcare Workers on Endothelial Function
Status: RECRUITING
Conditions: Healthy Volonteers
Interventions: BEHAVIORAL: On-duty Nap|BEHAVIORAL: Control condition (30-min rest)|DEVICE: EndoPAT|DEVICE: Popmeter®|DEVICE: Panasonic EW3109|DEVICE: ECG Holter|BIOLOGICAL: Fasting blood sample|OTHER: Pichot fatigue scale|OTHER: French version of the Recovery Needs Scale (BRD)|OTHER: The Short-Form 36 (SF-36)|OTHER: Pittsburgh Sleep Quality Index (PSQI)|OTHER: Epworth questionnaire|OTHER: The Karolinska Sleepiness Scale|DEVICE: Actimeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diindolylmethane in Treating Patients Undergoing Surgery for Stage I or Stage II Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Prostate Cancer|Stage I Prostate Cancer|Stage II Prostate Cancer
Interventions: DRUG: diindolylmethane|DRUG: placebo|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of the Shenzhen Trivalent Inactivated Influenza Vaccine Versus a Trivalent Influenza Vaccine Comparator in Chinese Subjects 18 to 59 Years
Status: COMPLETED
Conditions: Influenza|Flu
Interventions: BIOLOGICAL: SP Shz TIV|BIOLOGICAL: Hualan TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Chlorhexidine Cleansing on Bacteria Colonizing the Umbilical Cord of Infants in Bangladesh
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Chlorhexidine 4.0%|BEHAVIORAL: Dry Cord Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetic Profiles of Single 14 mg Teriflunomide Tablet in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Teriflunomide HMR1726|DRUG: cholestyramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hand-Foot Exercises on Chemotheraphy Induced Peripheral Neuropathy Pain, Falls and Quality of Life in Colorectal Cancer
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy|Colorectal Cancer
Interventions: OTHER: Hand-foot exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the HIV gp120/NefTat/AS02A Vaccine to Treat Individuals With Chronic HIV-1 Infection on Highly Active Antiretroviral Therapy (HAART)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV gp120/NefTat/AS02A Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Oral S-1 Plus Docetaxel in Elderly Patients With Advanced Gastric Cancer.
Status: SUSPENDED
Conditions: Gastric Cancer
Interventions: DRUG: Taxotere|DRUG: TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Intravenous Zanamivir on Cardiac Conduction in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: 600 mg zanamivir + moxifloxacin placebo|DRUG: 1200 mg zanamivir + moxifloxacin placebo|DRUG: zanamivir placebo + moxifloxacin placebo|DRUG: zanamivir placebo + 400 mg moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Measures for Bioaerosol Reduction in the Salmon Industry
Status: ENROLLING_BY_INVITATION
Conditions: Asthma, Occupational|Hypersensitivity
Interventions: OTHER: Nozzles (NZ)|OTHER: Cleaning of surfaces (CS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of Ertugliflozin in Healthy Male Participants (MK-8835-020)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Unlabeled ertugliflozin for oral use|DRUG: 14^C-labeled ertugliflozin for IV use|DRUG: 14^C-labeled ertugliflozin for oral use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oxygen Interventions and Defibrillator Efficiency
Status: TERMINATED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: Cardioversion with a pulsed biphasic waveform|PROCEDURE: Normoxia during cardioversion|DEVICE: Cardioversion with a biphasic truncated exponential waveform|PROCEDURE: Hyperoxia during cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of T900607-Sodium in Subjects With Previously Treated Gastric Cancer or Adenocarcinoma of the Esophagus
Status: SUSPENDED
Conditions: Gastric Cancer|Esophageal Neoplasms
Interventions: DRUG: T900607-sodium intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Training on Vascular Function as a Therapeutic Target in Pulmonary Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: BEHAVIORAL: Endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Collagen Dermal Filler With Lidocaine for the Correction of Nasolabial Folds
Status: UNKNOWN
Conditions: Nasolabial Fold
Interventions: DEVICE: Sunmax FULLSGEN with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Consequences of Human Inactivity
Status: COMPLETED
Conditions: Inactivity|Obesity|Type 2 Diabetes
Interventions: BEHAVIORAL: female inactivity and hypercaloric diet|BEHAVIORAL: inactivity|BEHAVIORAL: inactivity and hypercaloric diet|BEHAVIORAL: normal activity and hypercaloric diet|BEHAVIORAL: inactivity and iso-caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Histopathological Comparison Between Superficial Pressure Ulcers and Incontinence-associated Dermatitis
Status: COMPLETED
Conditions: Pressure Ulcer|Incontinence-associated Dermatitis|Irritant Contact Dermatitis|Diaper Rash
Interventions: PROCEDURE: Punch skin biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Novel Contact Force Sensing Catheter for AF Ablation - Impact of TactiCath on Dormant Conduction Across the Pulmonary Veins
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: AF Ablation with contact force information|PROCEDURE: AF Ablation without contact force information
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fetal Growth Restriction: Management Using Two Guidelines - Fetal Growth Antenatal Management Evaluation
Status: NOT_YET_RECRUITING
Conditions: Fetal Growth Retardation
Interventions: OTHER: Ultrasound following the SMFM guidelines|OTHER: Ultrasound following the ISUOG guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Different Routes and Doses of Phytonadione (Vitamin K) for Reversing Warfarin Treated Patients With Hip Fracture Before Surgery
Status: WITHDRAWN
Conditions: Bleeding|Complications
Interventions: DRUG: Phytonadione|DRUG: Phytonadione
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Trientine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5 Fraction Stereotactic Body Radiation Therapy for Oligometastases Regimen, for Extra-Cranial Oligometastases
Status: COMPLETED
Conditions: Solid Tumors With Oligometastatic Spread
Interventions: RADIATION: Radiation: 50Gy in 5 fr (max) to 25 Gy in 5 fr (min). Dose adapted to deliver the highest dose level while respecting normal tissue tolerance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological, Inflammatory and Metabolic Effects of Acute Mushroom Intervention in Older Adults
Status: COMPLETED
Conditions: Cognitive Change|Mood|Metabolism|Inflammatory Response|Satiety
Interventions: OTHER: Instant noodle soup containing containing the equivalent of 2 servings (18.78g) of powdered Pleurotus oyster mushroom.|OTHER: Instant noodle soup containing containing the equivalent of 1 serving (9.39g) of powdered Pleurotus oyster mushroom.|OTHER: Instant noodle soup containing containing the equivalent of 0.5 serving (4.70g) of powdered Pleurotus oyster mushroom.|OTHER: Control instant noodle soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HM11260C in Healthy Male Subject
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HM11260C|DRUG: HM11260C|DRUG: HM11260C|DRUG: HM11260C|DRUG: HM11260C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease Who Have Failed or Are Intolerant to Tumor Necrosis Factor (TNF) Antagonist Therapy (UNITI-1)
Status: COMPLETED
Conditions: Crohn's Disease|IBD|Colitis|Inflammatory Bowel Disease
Interventions: DRUG: Group 2 ustekinumab 130 mg|DRUG: Group 3: ustekinumab approximately 6 mg/kg|DRUG: Group 1: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malabsorption as a Cause of Iron Treatment Failure in Infants
Status: COMPLETED
Conditions: Iron Deficiency|Malabsorption
Interventions: DRUG: Metronidazole|PROCEDURE: Blood tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC