pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Medico-Economic Comparison of Four Strategies of Radioiodine Ablation in Thyroid Carcinoma Patients
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DRUG: Thyrogen, thyroid hormone withdrawal, iode 131
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine for Adolescent Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Transport Through Induced Membrane vs Conventional Bone Transport in Management of Bone Defects of Lower Limbs
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Loss
Interventions: PROCEDURE: bone transport through induced membrane|PROCEDURE: bone transport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Localized Prostate Cancer Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Quality of life assessment and Clinical evaluation|PROCEDURE: Radical retropubic prostatectomy surgery|RADIATION: External beam radiotherapy|RADIATION: Prostate Brachytherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety, Tolerability, and Immunogenicity Profiles of a Single Dose of V114, PNEUMOVAX® 23, or PREVNAR 13® in Adults 50 Years of Age or Older (V114-002)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Pneumococcal Conjugate Vaccine (V114)|BIOLOGICAL: PNEUMOVAX® 23|BIOLOGICAL: PREVNAR 13®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early and Late Prognosis in Patients With Guillain-Barre Syndrome
Status: RECRUITING
Conditions: Guillain-Barre Syndrome
Interventions: DRUG: Intravenous Immunoglobulins, Human|DRUG: Methylprednisolone 500 MG Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Secondary Distribution of HIV Self-screening Tests by Women With HIV
Status: COMPLETED
Conditions: HIV Infections|ART|HIV Seropositivity
Interventions: DIAGNOSTIC_TEST: HIV self test|BEHAVIORAL: Counseling and referral for partner testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasodilatory and Metabolic Effects of Glucagon-like Peptide-1 in Periphery Circulation in Patients With and Without Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes|Blod Pressure|Glucagon-like Peptide-1|Human Physiology|Blood Flow
Interventions: OTHER: human glucagon-like peptide 1 (7-36)amide|OTHER: human glucagon-like peptide 1 (9-36)amide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genotyping GUided Antiplatelet theRapy in pAtieNts Treated With Drug Eluting stEnts (GUARANTEE)
Status: RECRUITING
Conditions: Angina, Stable|Acute Coronary Syndrome|Drug-Eluting Stents|Genotype
Interventions: GENETIC: CYP2C19 genotype testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Clinical Performance of the ViaValve™ Safety IV Catheter
Status: COMPLETED
Conditions: Peripheral Intravenous Catheter
Interventions: DEVICE: ViaValve™ Safety IV Catheter|DEVICE: ProtectIV® Plus Safety IV Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Joint Disease|Pain, Acute|Pain, Chronic
Interventions: DRUG: Cymbalta|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free Flaps
Status: COMPLETED
Conditions: Optimal Tissue Perfusion
Interventions: OTHER: Fluid management|DRUG: Norepinephrine|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Recurrent Transitional Cell Bladder Cancer
Status: TERMINATED
Conditions: Recurrent Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: sunitinib malate|OTHER: immunohistochemistry staining method|OTHER: TdT-mediated dUTP nick end labeling assay|OTHER: light microscopy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ABT-888 in Combination With Bortezomib and Dexamethasone in Patients With Relapsed Refractory Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: ABT-888/Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentostatin and Rituximab in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: pentostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 'Melody' Paracentesis Device for Ascites Therapy
Status: COMPLETED
Conditions: Ascites Hepatic|Cirrhosis and Chronic Liver Disease
Interventions: DEVICE: standard device|DEVICE: Melody Device|DEVICE: Melody Device with Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Seeking Trial of PCK3145 in Asymptomatic, Castrate Metastatic Prostate Cancer Patients.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: PCK3145|DRUG: PCK3145
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Colon Cancer|Colorectal Cancer|Rectal Cancer
Interventions: DRUG: Placebo|DRUG: AMG 655|DRUG: Modified FOLFOX6|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prevention and Treatment Effects of Chinese Medicine on High Altitude Illness
Status: UNKNOWN
Conditions: Acute Mountain Sickness (AMS)
Interventions: DRUG: Chinese Medicine|DRUG: Acetalozamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study: Dynamic Contrast-enhanced Magnetic Resonance Imaging(DCE-MRI)for Assessing Tumor Vascularity and Permeability in Soft Tissue Sarcoma Treated With Preoperative Radiotherapy Followed by Surgical Resection
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: RADIATION: MRI-DCE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD?
Status: UNKNOWN
Conditions: Early Gastric Cancer|Gastric Dysplasia
Interventions: DRUG: aspirin and/or clopidogrel|DRUG: aspirin and/or clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors
Status: RECRUITING
Conditions: Intracranial Germ Cell CNS Tumor, Childhood
Interventions: RADIATION: Whole-ventricle irradiation|DRUG: Carboplatin/etoposide|DRUG: Ifosfamide/cisplatin/etoposide|PROCEDURE: Second-look surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZK-Epo Given With Carboplatin in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Sagopilone (ZK 219477) + carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREPARE-IT. Prevention and Treatment of COVID19 With EPA in Subjects at Risk - Intervention Trial
Status: COMPLETED
Conditions: COVID19
Interventions: DRUG: Icosapent ethyl (IPE)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ICG to Assess Ovarian Perfusion
Status: COMPLETED
Conditions: Fibroid Uterus|Endometriosis|Uterus Myoma|Uterine Fibroid|Uterine Adenomyosis|Endometrial Cyst|Uterine Cyst
Interventions: DRUG: ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SWOG-9346, Hormone Therapy in Treating Men With Stage IV Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: goserelin acetate|OTHER: clinical observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Formoterol Dose Ranging Study (ACHIEVE Duaklir USA Phase IIb)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease - COPD
Interventions: DRUG: Formoterol fumarate (6 μg)|DRUG: Formoterol furmarate (20 μg)|DRUG: Placebo for formoterol fumarate|DRUG: Formoterol fumarate (12 μg)|DRUG: Formoterol fumarate (40 μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise
Status: COMPLETED
Conditions: Muscle|Acute Exercise
Interventions: BEHAVIORAL: Traditional High Load Resistance Exercise (HLRE)|BEHAVIORAL: Low Load Resistance Exercise with Blood Flow Restriction (LLBFR)|BEHAVIORAL: Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extracellular microRNA: Biomarkers of Endothelial Dysfunction in Obese Adolescents & Adults With Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure|OTHER: Diet And Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of High-Flow Nasal Oxygen Versus Standard Oxygen Therapy in Critically Ill Immunocompromised Patients
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: PROCEDURE: standard oxygen|PROCEDURE: HFNO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise in Lessening Fatigue Caused by Cancer in Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotics and Breast Health
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DIETARY_SUPPLEMENT: Probiotic Natural Health Product - RepHresh Pro-B|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo to Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Polio|Human Immunodeficiency Virus Infection
Interventions: BIOLOGICAL: Hexaxim®: DTaP-IPV-HB-PRP-T Combined Vaccine|BIOLOGICAL: Hexaxim®: DTaP-IPV-HB-PRP-T Combined Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Atorvastatin on Viral Replication During Antiretroviral Treatment Interruption
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Atorvastatin 40 mg/Atorvastatin 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of ALLO-ASC-DFU for Second Deep Degree Burn Injury Subjects
Status: COMPLETED
Conditions: Burn Injury
Interventions: BIOLOGICAL: ALLO-ASC-DFU|DEVICE: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II
Status: RECRUITING
Conditions: Cervicogenic Headache|Whiplash Injuries
Interventions: OTHER: Dry Needling,Thrust Manipulation|OTHER: Exercise,Non-thrust Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Assisted Treatment of Fistula In Ano
Status: RECRUITING
Conditions: Fistula in Ano|Rectal Fistula
Interventions: PROCEDURE: Laser treatment of anal fistula|PROCEDURE: RAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis
Status: UNKNOWN
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Azithromycin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac and Renal Biomarkers in Arthroplasty Surgery
Status: TERMINATED
Conditions: Renal Injury|Anesthesia|Myocardial Injury|Arthropathy of Knee|Arthropathy of Hip
Interventions: DRUG: Spinal Anesthesia|DRUG: General Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease
Status: COMPLETED
Conditions: Aortic Stenosis|Aortic Regurgitation|Hypertension|LVM|Left Ventricular Hypertrophy
Interventions: DRUG: Amlodipine 5mg|DRUG: Losartan|DRUG: Losartan and Amlodipine|DRUG: Amlodipine/Losartan/Chlorthalidone|DRUG: current treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Low-frequency Transcranial Magnetic Stimulation Reduces Cue-induced Craving: a Randomized, Prospective, Double-blind, Sham-controlled, Cross-over Study
Status: TERMINATED
Conditions: Pathological Gambling
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coil Positioning in Navigated Transcranial Magnetic Stimulation Feasibility in Depression Patients Trial
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Navigated Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: LOU064 (blinded)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Cancer|Metastatic Cancer|Liver Metastases
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)
Status: COMPLETED
Conditions: Malaria in Pregnancy
Interventions: DRUG: Sulfadoxine pyrimethamine|DRUG: Pyramax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Angina Pectoris|Gene Transfer|Coronary Artery Disease
Interventions: DRUG: AdvVEGF-D|DRUG: Control Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Dengue With Obesity
Status: COMPLETED
Conditions: Dengue|Viral Infection|Metformin|Anti-inflammatory Agents|Obesity|Overweight
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravenous Ascorbic Acid
Status: COMPLETED
Conditions: Safety and Pharmacokinetics of Intravenous Ascorbate
Interventions: DRUG: IV Vitamin C|DRUG: IV Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Monitor the Incidence of Pure Red Cell Aplasia (PRCA) and/or Antibodies to Erythropoietin Among Participants Receiving Epoetin Alfa or Another Erythropoietin
Status: COMPLETED
Conditions: Red-Cell Aplasia, Pure|Chronic Renal Failure
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Novel Machine Learning Mobile App on Diet Adherence in Individuals Following the Low Fodmap Diet
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: OTHER: Heali mobile application + Registered Dietitian|OTHER: Heali mobile application|OTHER: Standard Dietary Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Acute Cholecystitis|Gangrenous Cholecystitis
Interventions: PROCEDURE: Laparoscopic cholecystectomy with the implementation of modified ERAS program|PROCEDURE: Laparoscopic cholecystectomy with standard perioperative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Accuracy of the Clinical Parameters & Radiographs in Determining the Topography of Implant Bony Lesions
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: DEVICE: Guidor® and Guidor easy-graft® CRYSTAL|DEVICE: Guidor® and Guidor easy-graft® CLASSIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Colorectal Liver Metastases: Novel Assessment Tools for Technical Resectability
Status: UNKNOWN
Conditions: Cancer|Cancer Metastatic|Colorectal Cancer|Liver Metastasis Colon Cancer
Interventions: DIAGNOSTIC_TEST: LiMAx test|DIAGNOSTIC_TEST: HepaT1ca magnetic resonance scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining Relationships Between Family Mealtime and Feeding Outcomes in Young Children With Sensory Food Aversions
Status: COMPLETED
Conditions: Feeding Disorder of Infancy or Early Childhood
Interventions: BEHAVIORAL: Mealtime PREP (Promoting Routines of Exploration and Play)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction.
Status: UNKNOWN
Conditions: Cocaine Addiction
Interventions: DEVICE: Deep brain stimulation of the subthalamic nuclei (STN-DBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Biases Modification Treatment for Social Anxiety
Status: COMPLETED
Conditions: Social Phobia
Interventions: BEHAVIORAL: Attention Bias Modification Treatment (ABMT)|BEHAVIORAL: Interpretation Bias Modification (IBM)|BEHAVIORAL: Control Condition|BEHAVIORAL: Attention and Interpretive biases modification (CBM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing Pitavastatin and Atorvastatin in Patients With Type II Diabetes Mellitus and Combined Dyslipidemia
Status: COMPLETED
Conditions: Type II Diabetes Mellitus|Dyslipidemia
Interventions: DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating SCA-136 in Subjects With Acute Exacerbations of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SCA-136 (200 mg)|DRUG: SCA-136 (400 mg)|DRUG: olanzapine (15 mg)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of rhBMP-2/ACS With the INTERFIX™ Device for the AnteriorLumbar Interbody Fusion in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/ACS/INTERFIX™|DEVICE: Autogenous bone/INTERFIX™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Borderline Resectable Pancreatic Cancer
Interventions: DRUG: gemcitabine/nab-paclitaxel|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Multi-center Trial to Evaluate Safety and Efficacy of Cohesive Silicone Gel-Filled Breast Implants UNIGEL®
Status: TERMINATED
Conditions: Breast Augmentation
Interventions: DEVICE: UNIGEL Silicone Gel-Filled Breast Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety, Tolerability and Pharmacokinetics of AZD5213 After Single and Multiple Ascending Oral Doses in Healthy Young and Elderly Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5213|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect and Mechanism of Remimazolam Benzenesulfonate on Enhanced Recovery After Surgery in Patients Undergoing Radical Gastrectomy for Gastric Cancer
Status: RECRUITING
Conditions: Remimazolam Benzenesulfonate on Nenhanced Recovery After Surgery|Possible Molecular Mechanism of Remimazolam Benzenesulfonate
Interventions: PROCEDURE: Remimazolam Benzenesulfonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calorimetry, Insulin Resistance and Energy Metabolism Study to Understand the Risk of Obesity in Kidney Transplanted Patients
Status: COMPLETED
Conditions: Chronic Renal Failure|Kidney Transplantation|Weight Gain|Insulin Resistance|Diabetes
Interventions: OTHER: Energy expenditure evaluation in calorimetric chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dose-Finding Study To Evaluate The Efficacy, Tolerability And Safety Of Fesoterodine In Comparison To Placebo For Overactive Bladder.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: fesoterodine fumarate|DRUG: Placebo|DRUG: fesoterodine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy
Status: COMPLETED
Conditions: Pain After Stapled Haemorrhoidopexy
Interventions: DRUG: 0.4% nitroglycerin ointment|DRUG: lidocaine cloridrato 2.5% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Otitis Media|Tonsillitis|Pharyngitis|Bronchitis
Interventions: DRUG: Clarithromycin DST (125 mg)|DRUG: Clarithromycin DST (187.5 mg)|DRUG: Clarithromycin DST (250 mg)|DRUG: Clarithromycin Syrup (125 mg)|DRUG: Clarithromycin Syrup (187.5 mg)|DRUG: Clarithromycin Syrup (250 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Carboplatin Versus Docetaxel as Second Line Treatment in Patients With Non-Small-Cell Lung Carcinoma (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare the Efficacy and Safety of NNC0195-0092 (Somapacitan) With Placebo and Norditropin® FlexPro® (Somatropin) in Adults With Growth Hormone Deficiency.
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency
Interventions: DRUG: somapacitan|DRUG: somatropin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effects of Heating Device (Electronic Moxibustion) in Patients With Intradialytic Hypotension
Status: COMPLETED
Conditions: Hemodialysis-Induced Symptom|Intra-dialytic Hypotension
Interventions: DEVICE: "HEALTHY BOX" Powered heating pad (electronic moxibustion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study of AV-380 in Healthy Subjects
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: AV-380|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Pharmacodynamic Effects and Pharmacokinetics of KUC 7483 CL in Patients With Spinal Cord Injury and Neurogenic Detrusor Overactivity
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: KUC 7483 CL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Different Radiation Dose of Neoadjuvant Chemoradiation for Resectable Thoracic Esophageal Squamous Carcinoma
Status: UNKNOWN
Conditions: Esophageal Carcinoma|Neoadjuvant Chemoradiotherapy|Surgery
Interventions: RADIATION: Higher dose (50.4Gy/28F) of neoadjuvant chemoradiation|RADIATION: Lower dose (41.4Gy/23F) of neoadjuvant chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation on Standardized Circuits of the Interest of a Robotic Module of Assistance to the Driving
Status: COMPLETED
Conditions: Neurological Disorder
Interventions: DEVICE: Electric wheelchair with activated assistance module|DEVICE: Electric wheelchair with assistance module not activated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Therapeutic Photobiomodulation and Tretament of Spasticity
Status: NOT_YET_RECRUITING
Conditions: Muscle Spasticity|Cerebral Palsy|Photobiomodulation|Low-Level Laser Therapy
Interventions: RADIATION: Photobiomodulation|OTHER: Institution's Standard Physiotherapy|RADIATION: Photobiomodulation Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sacubitril/Valsartan Treats Patients With Essential Hypertension and Type 2 Diabetic Nephropathy
Status: NOT_YET_RECRUITING
Conditions: Essential Hypertension|Type 2 Diabetes|Nephropathy
Interventions: DRUG: Sacubitril/Valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Internet Therapy for Chronic Illness (@LIIT.CI)
Status: COMPLETED
Conditions: Chronic Medical Conditions
Interventions: BEHAVIORAL: LIIT.CI ACT|BEHAVIORAL: LIIT.CI CFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-procedural Transthoracic EChocardiogram to Facilitate Left Bundle Branch Area Pacing (LBBAP)
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Heart Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Preconceptional Care and Counseling, Risk Awareness, Healthy Lifestyle Behavior
Status: COMPLETED
Conditions: Web
Interventions: BEHAVIORAL: WEB-BASED PRECONCEPTİONAL CARE AND COUNSELİNG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Thinning the Blood During Surgery Prevent Blood Clots Following Total Knee Replacement Surgery
Status: COMPLETED
Conditions: DVT|Osteoarthritis
Interventions: DRUG: unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56
Status: COMPLETED
Conditions: Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing the Incidence of Steal Syndrome in the Two Types of anTEcubitaL Fossa Arteriovenous fistuLa AVF
Status: COMPLETED
Conditions: Arteriovenous Fistulas|Renal Failure, End-Stage|Steal Syndrome
Interventions: PROCEDURE: Proximal radial/ulnar artery as inflow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-lumefantrine combination|DRUG: Artemether-lumefantrine combination + single dose Ivermectin|DRUG: Artemether-lumefantrine combination + repeated dose Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active You: Walk, Dance, and Tone Your Abs to Reduce Your Risk of Diabetes
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: PATH Intervention|BEHAVIORAL: Control Group|DEVICE: Physical activity tracker|BEHAVIORAL: Dietary education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Evaluating Daily Oral Doses of TLC-3595 in Participants With Insulin Resistance
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Resistance
Interventions: DRUG: TLC-3595 Dose 1|DRUG: TLC-3595 Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Occult Malignancy in Patients With Unprovoked Venous Thromboembolism
Status: RECRUITING
Conditions: Embolism and Thrombosis
Interventions: DIAGNOSTIC_TEST: Limited cancer screening|DIAGNOSTIC_TEST: Limited cancer screening + FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate the Effect of Lemborexant Versus Placebo on Driving Performance in Healthy Adult and Elderly Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Placebo tablet matching lemborexant|DRUG: Placebo tablet matching zopiclone|DRUG: Zopiclone 7.5 mg|DRUG: Lemborexant 2.5 mg|DRUG: Lemborexant 5 mg|DRUG: Lemborexant 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: D-cycloserine Augmented Treatment for Youth With Tic Disorders
Status: WITHDRAWN
Conditions: Tourette Syndrome
Interventions: DRUG: d-cycloserine|DRUG: Placebo pill|BEHAVIORAL: Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micronutrient Sprinkles in a Daycare Center
Status: COMPLETED
Conditions: Diarrhea|Respiratory Infection
Interventions: DIETARY_SUPPLEMENT: Micronutrient Sprinkles with zinc|DIETARY_SUPPLEMENT: Micronutrient sprinkles without zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of Drug-drug Interaction Between Ritonavir and TMC435350 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TMC435350 200 mg|DRUG: Ritonavir 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZMATICS: AZithroMycin/Asthma Trial In Community Settings
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XELOX With Capecitabine Maintenance or XELOX in Elderly Metastatic Adenocarcinoma of Stomach
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microcirculatory Status After Intravascular Lithotripsy
Status: COMPLETED
Conditions: Chronic Coronary Insufficiency|Coronary Artery Disease
Interventions: DEVICE: Shockwave® Intravascular Lithotripsy System (Shockwave Medical Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Automated Propofol Delivery in Patients Undergoing Thoracic Surgery
Status: COMPLETED
Conditions: Thoracic Diseases|Surgery
Interventions: DRUG: Propofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Postprandial Glucose Control Associated With BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BIOD-531|DRUG: Humalog Mix 75/25|DRUG: Humulin R U-500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Active-Controlled, Dose-Ranging Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Celgosivir hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Status: WITHDRAWN
Conditions: ACL Injury
Interventions: DIETARY_SUPPLEMENT: Protein (PROT)|OTHER: Control (CONT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Triplezumab Combined With CAPEOX Regimen in Neoadjuvant Therapy for Locally Advanced Colon Cancer
Status: UNKNOWN
Conditions: Locally Advanced Colon Cancer
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Talsaclidine (Free Base) in Patients With Mild to Moderate Dementia of Alzheimer Type
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Talsaclidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Efficacy and Safety of BCD-085 (Monoclonal Anti-IL-17 Antibody) in Psoriatic Arthritis
Status: UNKNOWN
Conditions: Psoriatic Arthritis
Interventions: DRUG: BCD-085|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Oral S-1 Plus Irinotecan (IRIS) in Patients With Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Campto, Topotesin|DRUG: TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Intervention in the Development of Clinical Research in Non-Academic Health Institution (ERNU)
Status: COMPLETED
Conditions: Clinical Research|Cancer
Interventions: BEHAVIORAL: interventions of the Cancéropôle Nord-Ouest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Lung Edema After Thoracic Surgery
Status: COMPLETED
Conditions: Lung Injury, Acute|Thoracotomy|Anesthesia|Intensive Care, Surgical|Extravascular Lung Water
Interventions: DRUG: inhalation of salbutamol (5 mg)|DRUG: ipratropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome
Status: RECRUITING
Conditions: Down Syndrome
Interventions: OTHER: Routine Physiotherapy Group|OTHER: Orofacial Treatment Group|OTHER: Therapeutic Yoga Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Once Monthly Bonviva (Ibandronate) in Prevention of Glucocorticoid-Induced Osteoporosis.
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Placebo|DRUG: ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MILES-4: Study Comparing Gemcitabine and Pemetrexed, With or Without Cisplatin, in Patients With Nonsquamous Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Stage IIIB
Interventions: DRUG: Gemcitabine|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab and Lenvatinib for Conversion Therapy in Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Cadonilimab and Lenvatinib
Interventions: DRUG: Cadonilimab lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immune Response to the ASP7374 and Its Safety in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy|Immunogenicity of ASP7374
Interventions: BIOLOGICAL: ASP7374
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetic Gastroparesis
Interventions: DRUG: Metoclopramide Nasal Spray|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Rituximab and High-dose Dexamethasone as First Line Treatment for ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Rituximab and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normothermic Machine Perfusion (NMP) Versus Hypothermic Machine Perfusion (HMP) in Human Kidney Transplantation
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplantation
Interventions: DEVICE: Normothermic machine perfusion|DEVICE: Hypothermic machine perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus Anti-PD-1 Antibody AK105 for Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Anlotinib|Anti-PD-1 Antibody|Advanced Pancreatic Cancer
Interventions: DRUG: Anlotinib plus AK105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of SK SARS-CoV-2 Recombinant Nanoparticle Vaccine (GBP510) Adjuvanted With AS03 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: GBP510 adjuvanted with AS03 (Receptor-Binding Domain(RBD) 25ug/dose)|BIOLOGICAL: ChAdOx1-S not less than 2.5 × 10^8 infectious units|BIOLOGICAL: GBP510 adjuvanted with AS03 (Receptor-Binding Domain(RBD) 25ug/dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kidney Yin/Yang Replenishment on Patients With Renal Osteodystrophy
Status: WITHDRAWN
Conditions: Renal Insufficiency, Chronic|Renal Osteodystrophy
Interventions: DRUG: Yougui granules|DRUG: Zuogui granules|DRUG: Yougui granules placebo|DRUG: Zuogui granules placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protein Supplementation and Recovery of Muscle Function
Status: UNKNOWN
Conditions: Resistance Training|Muscle Damage
Interventions: DIETARY_SUPPLEMENT: CONTROL|DIETARY_SUPPLEMENT: Whey Protein Concentrate|DIETARY_SUPPLEMENT: Whey Protein Hydrolysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE