pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Platinum-Resistant Ovarian Carcinoma
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filgrastim With or Without Plerixafor in Treating Patients With Multiple Myeloma Previously Treated With Lenalidomide
Status: TERMINATED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: plerixafor|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Cortex as a Research & Therapeutic Target in TMD
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: DEVICE: High-Definition Transcranial Direct Current Stimulation (HD-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers
Status: RECRUITING
Conditions: Metastatic Cancer
Interventions: DRUG: Nivolumab Standard|DRUG: Pembrolizumab Standard|DRUG: Nivolumab Extended|DRUG: Pembrolizumab Extended
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Arbidol (Umifenovir) for Treatment and Prophylaxis of Influenza and Common Cold
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Arbidol (Umifenovir)|OTHER: placebo|DRUG: Arbidol (Umifenovir)|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of New Generation Bednets in the Context of Conventional Insecticide Resistance in the Democratic Republic of the Congo
Status: UNKNOWN
Conditions: Insecticide Resistance
Interventions: DRUG: synergistic combination of insecticides|DRUG: Pyrethroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma
Status: UNKNOWN
Conditions: Superficial Basal Cell Carcinoma|Nodular Basal Cell Carcinoma
Interventions: DRUG: EscharEx 5% (EX-02 formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Platelet Rich Fibrin Membrane on the Neurosensory Dysfunction After IAN Lateralization for Implant Placement.
Status: UNKNOWN
Conditions: Neurosensory Disorder
Interventions: PROCEDURE: inferior alveolar nerve lateralization and dental implant placement.|PROCEDURE: platelet rich fibrin membrane around the nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intensive Fly Control on Trachoma and Ocular Chlamydia Infection in Tanzania
Status: COMPLETED
Conditions: Trachoma
Interventions: PROCEDURE: 10% permethrin in water applied as low volume spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Haem and Nitrite Study - The Effects of Haemoglobin NO-blockade on Nitrite-induced Forearm Vessel Dilatation
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Sodium Nitrite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carfilzomib, Pegylated Liposomal Doxorubicin Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: carfilzomib|DRUG: pegylated liposomal doxorubicin (PLD)|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: English Mammography Screening Outcomes by Age, Frequency and Test Threshold
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: OTHER: Increase in upper age of eligibility for breast cancer screening from 64 to 70|OTHER: Screening round length|DIAGNOSTIC_TEST: Screening test threshold
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iTBS for Increased Appetite Induced by Antipsychotics
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: Active iTBS|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Serrated Polyps and High-grade Dysplasia at Index Colonoscopy on Risk of Metachronous High-risk Adenomas
Status: RECRUITING
Conditions: Colorectal Cancer|Colon Adenoma
Interventions: DIAGNOSTIC_TEST: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Autologous Transplantation of iPSC-RPE in the Treatment of Macular Degeneration
Status: RECRUITING
Conditions: Macular Degeneration
Interventions: BIOLOGICAL: Autologous iPSC-derived RPE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Intervention for Pain Study (TIPS)
Status: COMPLETED
Conditions: Chronic Pain|Multiple Sclerosis|Amputation|Spinal Cord Injury
Interventions: BEHAVIORAL: Telephone-Delivered Intervention 1|BEHAVIORAL: Telephone-Delivered Intervention 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension
Status: COMPLETED
Conditions: Arterial Hypertension|Hypertension, Resistant to Conventional Therapy|Diabetes Mellitus
Interventions: DRUG: spironolactone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genotype Based Personalized Prescription of Nevirapine
Status: COMPLETED
Conditions: Nevirapine Induced Rash|Nevirapine Induced Hepatitis|HIV|Adverse Side Effects|AIDS|HIV Infections
Interventions: GENETIC: Genetic test for NVP induced rash|OTHER: 3TC/D4T/NVP or 3TC/AZT/NVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8|Solid Tumor, Adult|Solid Tumor|Metastatic Castration-resistant Prostate Cancer
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|DRUG: 11C-YJH08|PROCEDURE: Optional Tumor Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Wine Grape Pomace Flour Used as a Dietary Supplement on Metabolic Syndrome Components
Status: COMPLETED
Conditions: Metabolic Syndrome X|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Red wine grape pomace flour (WGPF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy of ABC for High-Risk Parent and Infants
Status: UNKNOWN
Conditions: Attachment Disorders
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-up (ABC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LEAP-Ireland Feasibility Trial of Exercise and Education for Gluteal Tendinopathy
Status: RECRUITING
Conditions: Gluteal Tendinopathy|Trochanteric Bursitis|Greater Trochanteric Pain Syndrome
Interventions: OTHER: EDucation and eXercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Weekly ALTU-238 Compared With Daily Nutropin AQ in Prepubertal Children With Growth Hormone Deficiency
Status: UNKNOWN
Conditions: Growth Hormone Deficiency
Interventions: DRUG: Somatropin|DRUG: Somatropin|DRUG: Somatropin|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-dimensional Virtual Imaging to Improve the Accuracy of Standard CT-based Nephrometric Scores: a Prospective Multicentric Observational Study
Status: COMPLETED
Conditions: Kidney Neoplasms|Carcinoma, Renal Cell
Interventions: OTHER: 3D-PADUA nephrometric score|OTHER: 2D-PADUA nephrometric score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
Status: COMPLETED
Conditions: Malocclusion|Orthodontic Appliance Complication
Interventions: DEVICE: hours of use (Essix)|OTHER: collect saliva|OTHER: collect biofilm|OTHER: collect epithelium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery
Status: RECRUITING
Conditions: Etomidate|Hypotension
Interventions: DRUG: Etomidate - propofol mixture|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of PTK787/ZK 222584 Plus Paclitaxel
Status: TERMINATED
Conditions: Metastatic Non-hematologic Malignancies
Interventions: DRUG: PTK787/ZK 222584|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Rates of Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: CBT MobileWork-V plus CBT|BEHAVIORAL: CBT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Dialectical Behavior Therapy and Digital Cognitive Behavioral Therapy for Insomnia for Adolescents at High Risk for Suicide
Status: RECRUITING
Conditions: Suicide and Self-harm
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Ribocilcib (LEE011) and Weekly Paclitaxel in Patients With Rb+ Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Ribociclib (LEE011)|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening the Spleen and Reducing Phlegm Method in Improving Radical Resection Rate of Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Jianpi Huatan dispensing granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Impact of an Intervention to Prevent Intimate Partner Violence and HIV in Uganda
Status: COMPLETED
Conditions: HIV|Physical Abuse of Adult (If Focus of Attention is on Victim)|Sexual Abuse of Adult (If Focus of Attention is on Victim)|Risk Reduction Behavior
Interventions: BEHAVIORAL: The SHARE Project
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study To Evaluate The Efficacy And Safety Of PH-797804 For 12 Weeks In Adults With Moderate To Severe Chronic Obstructive Pulmonary Disease (COPD) Taking Salmeterol Xinafoate/Fluticasone Propionate Combination
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: PH-797804|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: DRUG: Paclitaxel|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Program of Food Preparation on Diet Improvement for Patients With Stroke
Status: COMPLETED
Conditions: Stroke|Dysphagia, Late Effect of Stroke
Interventions: OTHER: Group swallowing disorder diet preparation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Task-oriented Circuit Training on Gait Kinematics, Pelvic Symmetry and Endurance in Children With Hemiplegia
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Task-oriented circuit training|OTHER: Selected Physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Lactobacillus Reuteri in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Lactobacillus reuteri|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Biomarkers of Skin Androgenization Following Testosterone Administration (0000-015)(COMPLETED).
Status: COMPLETED
Conditions: Skin Androgenization
Interventions: DRUG: testosterone gel|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Herring Oil Concentrate on LDL Cholesterol Concentration in Adults
Status: NOT_YET_RECRUITING
Conditions: High Cholesterol
Interventions: DIETARY_SUPPLEMENT: Herring oil concentrate|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intracavernosal Injection of Botulinum Toxin Type A (50 and 100 Unit) in the Treatment of Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction|Botulinum Toxin
Interventions: OTHER: saline injection|BIOLOGICAL: Botulinum toxin type A 50 units|BIOLOGICAL: Botulinum toxin type A 100 units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma|Relapsed Peripheral T-Cell Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Anaplastic Large Cell Lymphoma|Mycosis Fungoides|Relapsed Anaplastic Large Cell Lymphoma|Relapsed Mycosis Fungoides
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter|PROCEDURE: Single Photon Emission Computed Tomography|BIOLOGICAL: Cemiplimab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Lisdexamfetamine to Treat Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression
Interventions: DRUG: Lisdexamfetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea|COPD Exacerbation|Overlap Syndrome
Interventions: DEVICE: continuous positive airway pressure treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
Status: RECRUITING
Conditions: Autonomic Failure|Pure Autonomic Failure|Multiple System Atrophy|Parkinson Disease|Orthostatic Hypotension
Interventions: DRUG: Droxidopa|DRUG: Midodrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study
Status: COMPLETED
Conditions: Hypoxia|Desaturation of Blood
Interventions: DEVICE: Non-Invasive Controlled Hypoxia|OTHER: Introduction of Motion conditions: tapping or rubbing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Pilot Study on Budesonide/Formoterol Device-metered Dry Powder Inhalers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol 320/9 μg and 400/12 μg inhalers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Sargramostim (GM-CSF, Leukine)|DRUG: Flutamide (Eulexin)|BIOLOGICAL: PROSTVAC-F/ TRICOM|BIOLOGICAL: PROSTVAC-V/TRICOM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration as a Treatment for Parkinson's Disease
Status: UNKNOWN
Conditions: Idiopathic Parkinson's Disease|Primary Parkinsonism
Interventions: DEVICE: vibrating chair|DEVICE: sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function
Status: COMPLETED
Conditions: Delayed Graft Function
Interventions: DRUG: OPN-305|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Status: SUSPENDED
Conditions: Infertility
Interventions: PROCEDURE: In vitro maturation and in vitro fertilization|PROCEDURE: Low doses of gonadotropin stimulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms
Status: COMPLETED
Conditions: Postmenopause
Interventions: BEHAVIORAL: Breathing training|BEHAVIORAL: Stress management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex
Status: COMPLETED
Conditions: AIDS Dementia Complex|HIV Infections
Interventions: DRUG: Abacavir sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Skin Rash|Skin Toxicities|Colon Cancer|Colorectal Cancer
Interventions: BIOLOGICAL: Panitumumab|DRUG: Irinotecan|DRUG: FOLFIRI|DRUG: Pre-emptive Skin Treatment|DRUG: Reactive Skin Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pain Relief Efficacy of Epidural Analgesia and Erector Spinae Plane Block Before Thoracotomy Surgery
Status: RECRUITING
Conditions: Thoracotomy Surgery
Interventions: PROCEDURE: Thoracic Epidural Analgesia|PROCEDURE: Erector spinae plane block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Re-feeding Gastric Residuals in Preterm Infants
Status: COMPLETED
Conditions: Premature; Infant, Light-for-dates
Interventions: PROCEDURE: Re-feeding residuals|PROCEDURE: Fresh Feeding Breastmilk or Formula only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E Test Strips Applied to Bronchoalveolar Lavage for Suspicion of Hospital-acquired Pneumonia to Accelerate Antibiogram Analysis.
Status: COMPLETED
Conditions: Hospital-acquired Pneumonia
Interventions: OTHER: E test method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Intranasal Oxytocin Effects Using Co-administration With a Vasoconstrictor
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: vasoconstrictor and oxytocin treatment|DRUG: vasoconstrictor's placebo and oxytocin treatment|DRUG: vasoconstrictor and oxytocin's placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiple Ascending Dose Study of TD-1439 in Healthy Adult and Elderly Subjects
Status: COMPLETED
Conditions: Healthy Adults, Elderly Subjects
Interventions: DRUG: TD-1439|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Dose Vitamin C in the Critically Ill Patient
Status: TERMINATED
Conditions: Shock
Interventions: DRUG: Ascorbic Acid|OTHER: Ringers Lactate or Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Efficacy and Safety of Infant Peri-exposure Prophylaxis With Lopinavir/Ritonavir Versus Lamivudine to Prevent HIV-1 Transmission by Breastfeeding
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: lopinavir/ritonavir (LPV/r)|DRUG: Lamivudine (3TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure.
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Mantle Cell Lymphoma Refractory
Interventions: DRUG: Glofitamab|DRUG: Pirtobrutinib|DRUG: Obinutuzumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Functional Outcome of Site Peroneus Longus Graft Donors With and Without Distal Stump Suturing of Peroneus Tendon Brevis on ACL Reconstruction Case in Cipto Mangunkusumo Hospital in Jakarta With 24 Patient as Subject Who Will Divide Into 2 Group.
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: Distal Stump Suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT).
Status: COMPLETED
Conditions: Rendu Osler Disease|Telangiectasia, Hereditary Hemorrhagic
Interventions: DRUG: Bevacizumab|DRUG: sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab for High Risk SMM and SLiM CRAB Positive, Early Myeloma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA]|DRUG: Placebo 1.7 ml Subcutaneous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PegIntron Treatment of Chronic Hepatitis B e Antigen-Positive Patients (P05170/MK-4031-327)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: pegylated interferon alpha-2b|DRUG: pegylated interferon alpha-2b|DRUG: pegylated interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Disinfection by Pulse Irrigation With Povidone-Iodine Solution in Spine Surgery
Status: COMPLETED
Conditions: Spinal Diseases|Spinal Fusion|Spine Injury|Infection, Hospital
Interventions: PROCEDURE: Group A - Pulsed PVP-I Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oropharyngeal Aspiration to Reduce Ventilator-Related Pneumonia
Status: COMPLETED
Conditions: Ventilator-associated Bacterial Pneumonia
Interventions: PROCEDURE: Oropharyngeal aspiration before changing the position of the patient|OTHER: Control group:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dietary Acid Load, Kidney Function and Disability in Elderly
Status: COMPLETED
Conditions: Chronic Kidney Disease|Disability
Interventions: DIETARY_SUPPLEMENT: Oral bicarbonate supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory (R/R) Aggressive B-Cell NHL
Status: COMPLETED
Conditions: B-Cell Non Hodgkin Lymphoma
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intimal Hyperplasia Evaluated by Optical Coherence Tomography (OCT) in de Novo Coronary Lesions Treated by Drug-eluting Balloon and Bare-metal Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: drug (paclitaxel)-eluting balloon (DEB)|DEVICE: bare-metal stent (BMS)|DEVICE: Drug (paclitaxel)-eluting balloon (DEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Front-of-package Label Effects in Latine and Limited English Proficiency Populations
Status: RECRUITING
Conditions: Diet, Healthy
Interventions: BEHAVIORAL: Guideline Daily Amounts label|BEHAVIORAL: Interpretive text-only label|BEHAVIORAL: Interpretive magnifying glass icon label|BEHAVIORAL: Separated interpretive magnifying glass icon label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Duloxetine Compared With Placebo in the Prevention of Relapse in Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: Duloxetine Hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: "Efficacy of Intermittent Enteral Nutrition Versus Continuous Administration in Intensive Care"
Status: RECRUITING
Conditions: Enteral Nutrition|Critical Care|Feeding Methods|Gastric Feeding Tube
Interventions: OTHER: INTERMITTENT ENTERAL NUTRITITION (IEN)|OTHER: CONTINUOS ENTERAL NUTRITITION (CEN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Sub-study of BMS-986036 in Subjects With Non-Alcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DRUG: BMS-986036|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Vascular Disease, Peripheral
Interventions: DEVICE: Shockwave Medical M5+ Peripheral Intravascular Lithotripsy (IVL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Rehabilitation for Older Patients With Acute Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: BEHAVIORAL: Rehabilitation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapulmonary Pharmacokinetics of XNW4107, Imipenem and Cilastatin in Healthy Subjects
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: XNW4107, Imipenem/Cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Registry to Evaluate Chinese Real-World Clinical Outcomes in Patients With AF Using the WATCHMAN Left Atrial Appendage Closure Technology
Status: UNKNOWN
Conditions: Non-valvular Atrial Fibrillation
Interventions: DEVICE: WATCHMAN LAA occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yinhu Qingwen Decoction for the Treatment of Mild / Common CoVID-19
Status: SUSPENDED
Conditions: CoVID-19|Chinese Medicine
Interventions: DRUG: YinHu QingWen Decoction|DRUG: YinHu QingWen Decoction(low dose)|OTHER: Chinese medicine treatment|OTHER: standard western medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: sargramostim|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|PROCEDURE: cryosurgery|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Bilateral Erector Spinae Plane Block in Retropubic Radical Prostatectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ultrasound guided erector spinae plane block|OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches
Status: UNKNOWN
Conditions: Corona Virus Infection|ARDS|Coinfection
Interventions: DIAGNOSTIC_TEST: Sampling (EDTA blood, pharyngeal and nose swabs, bronchoalveolar lavage ,urine)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PoC in Rheumatoid Arthritis With Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis, NOS
Interventions: DRUG: BMS-582949|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Extension Study of Iron Isomaltoside 1000 (Monofer®) in Subjects With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Anaemia
Interventions: DRUG: Monofer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial - Comparative Study of Two Material Concentration of OD-141309
Status: UNKNOWN
Conditions: Infectious Disease
Interventions: DRUG: Antimicrobial efficacy of gel ZHCK4 as a patient preoperative skin preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultramarathons and Impact of Phased Electromagnetic Field Therapy (PEMF)
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Pulsed Electromagnetic Field therapy (PEMF)|PROCEDURE: Pulsed Electromagnetic Field Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of Mycophenolate Mofetil in Congenital Uropathies
Status: COMPLETED
Conditions: Congenital Urological Abnormalities
Interventions: DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-gel Versus Classic-Laryngeal Mask Airway (C-LMA) as a Conduit for Tracheal Intubation Using Ventilating Bougie
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: DEVICE: Tracheal Intubation using I-gel and ventilating bougie|DEVICE: Tracheal Intubation using C-LMA and ventilating bougie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Preventive Effects of Cetylpyridinium Chloride on Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: Cetylpyridinium Chloride (CPC)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children
Status: UNKNOWN
Conditions: Growth Retardation
Interventions: DRUG: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of Midazolam Premedication
Status: COMPLETED
Conditions: Midazolam Premedication|Anxiety Preoperative|Premedication
Interventions: DRUG: Midazolam premedication|DRUG: Remifentanil infusion|DRUG: Propofol infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Vidicizumab Combined With Tirelizumab in the Treatment of Breast Cancer With Low HER2 Expression
Status: RECRUITING
Conditions: Breast Cancer|Neoadjuvant Therapy
Interventions: DRUG: Disitamab Vedotin combined with Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMLA Topical Anesthetic During Scaling and Root Planing
Status: COMPLETED
Conditions: Local Anesthesia|Pain, Postoperative|Self-Perception
Interventions: DRUG: EMLA|DRUG: Injectable anesthesia|DRUG: 2% Benzocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for Pediatric Hypertrophic Tonsils
Status: RECRUITING
Conditions: Pediatric Sleep Apnea|Obstructive Sleep Apnea|Tonsils Hypertrophy
Interventions: DEVICE: PBM Tonsil Arm|DEVICE: Sham PBM Tonsil Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perceptual, Hemodynamic and Cardiovascular Responses of Two Different BFR Training Protocols
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Autoregulated Blood Flow Restriction Cuff (smart-cuff pro devices, acting as pressurized tourniquet) combined with low load strength training|DEVICE: Non-autoregulated blood flow restriction cuff ((smart-cuff pro devices, acting as pressurized tourniquet) combined with low load strength training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Hypertension|Elevated Cholesterol|Overweight and Obesity
Interventions: OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Non-small Cell Lung Cancer With Cytokine-induced Killer (CIK) Cells Blocked by PD-1 Antibody
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: CIK cells with PD-1 blocking|OTHER: standard lung cancer treament|BIOLOGICAL: CIK cells without PD-1 blocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Mechanisms of Recovery Oriented Cognitive Therapy
Status: WITHDRAWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Recovery Oriented Cognitive Therapy (CT-R)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Perforation in Patients Receiving an Orthtopic Liver Transplantation in the Montpellier University Hospital
Status: COMPLETED
Conditions: Liver Transplantation|Intestinal Perforation|Digestive System Fistula|Intestinal Fistula
Interventions: PROCEDURE: Liver transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Endotracheal Cuff Pressure Changes According to Different Positions in Neurosurgery Cases
Status: NOT_YET_RECRUITING
Conditions: The Effect of Cuff Pressure on Postoperative Dysphagia
Interventions: OTHER: supine position|OTHER: prone position|OTHER: semi-fowler position
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Predicting, Understanding and Speeding Recovery After TKA
Status: TERMINATED
Conditions: Pain|Total Knee Replacement|Total Hip Replacement
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Skin Quality Improvement
Status: COMPLETED
Conditions: Skin Quality
Interventions: DRUG: Hyper-Diluted Botox|DRUG: Topical anesthesia|OTHER: 0.9% saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Tolerability, Safety, and Pharmacokinetics of Subcutaneous Immune Globulin Infusion 10% (Human) With Recombinant Human Hyaluronidase (HYQVIA/HyQvia) With Ramp-up and No Ramp-up Dosing in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: HYQVIA|DRUG: HYQVIA|DRUG: HYQVIA|DRUG: HYQVIA|DRUG: HYQVIA|DRUG: HYQVIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Iguratimod Combined With Tofacitinib in the Treatment of Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Iguratimod combined with Tofacitinib;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet Treatment Adjunctive to Radiation and Chemotherapy in Glioblastoma Multiforme: a Pilot Study
Status: COMPLETED
Conditions: Glioblastoma Multiforme of Brain
Interventions: OTHER: Ketogenic Diet|OTHER: Standardized Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBI-10090 in Ocular Surgery Patients
Status: COMPLETED
Conditions: Inflammation Associated With Cataract Surgery
Interventions: DRUG: IBI-10090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: DRUG: Read vine leaf extract (AS 195)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Combined Digital X-ray and Ultrasound Technique for Improved Detection and Characterization of Breast Lesions
Status: COMPLETED
Conditions: Breast Cancer|Mass Cystic|Benign Mass
Interventions: PROCEDURE: 3D Tomosynthesis and ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CNTO 328 in Subjects With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: CNTO 328
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Retraining in Improving Cognitive Function in Breast Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Stage 0 Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Computer-Assisted Cognitive Training|OTHER: Questionnaire Administration|PROCEDURE: Standard Follow-Up Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Probiotics on the Patients With End Stage Renal Disease (ESRD)
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Level Laser Therapy in Persistent Pelvic Girdle Pain
Status: UNKNOWN
Conditions: Pelvic Girdle Pain
Interventions: DEVICE: Active laser therapy|DEVICE: Sham laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma; Eosinophilic
Interventions: DRUG: Benralizumab|DRUG: 129 Xenon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block in Pediatric Patients
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: PROCEDURE: Serratus Anterior Plan Block+ Fentanyl infusion|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus Chemotherapy as First-line Therapy for Gastrointestinal Tumor Patients With Unresectable Liver Metastasis (ALTER-G-001)
Status: RECRUITING
Conditions: Gastrointestinal Tumors
Interventions: DRUG: Anlotinib + Oxaliplatin + Capecitabine|DRUG: Anlotinib + Cisplatin + Paclitaxel/ Docetaxel|DRUG: Anlotinib + Standard first-line chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT