pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Romosozumab in Women With Chronic SCI
Status: COMPLETED
Conditions: Osteoporosis|Bone Loss|Osteopenia, Osteoporosis|Spinal Cord Injuries|Chronic Spinal Paralysis
Interventions: DRUG: Romosozumab|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 150 μg|DRUG: Placebo to indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimum Effective Volume of Ropivacaine 7.5 mg/ml for the Lateral and Sagittal Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD|COPD Exacerbation|Pulmonary Rehabilitation|Weight Training|Virtual Reality|Muscle Strength|Pulmonary Function|Quality of Life|Readmission
Interventions: OTHER: Education|OTHER: Supervision upper limb weight training exercise with VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Sacituzumab Govitecan-hziy|DRUG: Eribulin Mesylate Injection|DRUG: Capecitabine Oral Product|DRUG: Gemcitabine Injection|DRUG: Vinorelbine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene
Status: COMPLETED
Conditions: HIV Infection|Alcohol Use|Pain
Interventions: DRUG: Low dose naltrexone|DRUG: Nalmefene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor and Anlotinib Combined With Multimodal Radiotherapy in Recurrent or Metastatic Anaplastic Thyroid Cancer
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: Tislelizumab|DRUG: Anlotinib|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Head Massage Therapy on the Regulation of the Autonomic Nervous System
Status: COMPLETED
Conditions: The Effect of Head Massage Therapy on the Autonomic Nervous System
Interventions: OTHER: Head Massage Therapy|OTHER: Simple relaxation (No Head Massage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erector Spinae Plane Block for Congenital Hip Dislocation Surgery
Status: COMPLETED
Conditions: Congenital Hip Dysplasia
Interventions: DRUG: Saline Solution|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant HIPEC in High Risk Colon Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Peritoneal Neoplasms
Interventions: PROCEDURE: Adjuvant HIPEC (open/laparoscopic)|DRUG: Standard adjuvant systemic chemotherapy|PROCEDURE: Diagnostic laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study
Status: COMPLETED
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: BEHAVIORAL: Cigarette Smoking|BEHAVIORAL: Cigarette Smoking|BEHAVIORAL: Cigarette Smoking|BEHAVIORAL: Cigarette Smoking|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Find a Suitable Dose of ASP2802 in People With CD20-positive B-cell Lymphomas
Status: RECRUITING
Conditions: B-cell Lymphoma
Interventions: DRUG: ASP2802|DRUG: MA-20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)
Status: COMPLETED
Conditions: Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)
Interventions: DRUG: UX007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Management of Hereditary Hemochromatosis: Phlebotomy vs. Erythrocytoapheresis
Status: COMPLETED
Conditions: Hereditary Hemochromatosis
Interventions: PROCEDURE: Eritrocytoapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacology of Oseltamivir (Tamiflu) in Pregnancy
Status: WITHDRAWN
Conditions: Pregnancy|Influenza
Interventions: DRUG: Oseltamivir (Tamiflu)|PROCEDURE: Blood Draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Comparing the Different Effect of DPP-4 Inhibitors and Sulfonylurea by Using "Biphase-Hyperglycemic Clamp"
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Saxagliptin|DRUG: Glimepiride|DRUG: Blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Psychosocial Adjustment After Radiation Therapy in Patients With Cancer
Status: COMPLETED
Conditions: Breast Cancer|Cognitive/Functional Effects|Colorectal Cancer|Lung Cancer|Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: questionnaire administration|PROCEDURE: cognitive assessment|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis
Status: COMPLETED
Conditions: Tuberculosis|Tuberculous Meningitis|Drug-Induced Liver Injury
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Restrictive Versus Liberal Transfusion Protocol in Infants Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Impaired Oxygen Delivery|Congenital Heart Disease
Interventions: OTHER: Red blood cell transfusion|OTHER: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial of Psilocybin Therapy in Palliative Care
Status: NOT_YET_RECRUITING
Conditions: Demoralization
Interventions: DRUG: Psilocybin|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The SINCERE Intervention to Address COVID-19 Health Disparities
Status: RECRUITING
Conditions: COVID-19|Vulnerable Populations|Social Determinants of Health
Interventions: BEHAVIORAL: SINCERE|BEHAVIORAL: Scheduled Follow-Up|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Electrode Implantation for Deep Brain Stimulation (DBS) on Brain Function Using Single Photon Emission Computed Tomography (SPECT) With Technetium-99m-ethyl Cysteinatedimer (Tc-ECD)
Status: UNKNOWN
Conditions: Parkinson's Disease|Deep Brain Stimulation
Interventions: RADIATION: Injection of 15mCi of Tc-ECD and scanning by SPECT camera|BEHAVIORAL: Semantic verbal fluency task performance|DEVICE: Turning off the stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation Between Quadratus Lumborum , Pelvic Floor Muscles and Diaphragm in Patients With Urinary Incontinence
Status: COMPLETED
Conditions: Correlation Between Quadratus Lumborum , Pelvic Floor Muscles and Diaphragm in Patients With Urinary Incontinence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)
Status: COMPLETED
Conditions: Anemia, Sickle Cell|Hematologic Diseases|Hemoglobinopathies
Interventions: DRUG: hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Test of Short and Long Term Naturalistic Outcomes of Smokers Who Sample Smokeless Tobacco
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: DRUG: Potentially Reduced Exposure Product (PREP): a smokeless, spit-free tobacco product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: COVID-19: Investigation of Transmission and Immunisation Among Hospital Staff
Status: COMPLETED
Conditions: COVID
Interventions: DIAGNOSTIC_TEST: IgM and IgG diagnostic kits to SARS-CoV-2|DIAGNOSTIC_TEST: Elisa-test for IgM and IgG to SARS-CoV-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Acamprosate in Treating Alcohol Use Disorder in the Post Liver Transplant Populations
Status: COMPLETED
Conditions: Alcohol Use Disorder|Liver Transplant; Complications
Interventions: DRUG: Acamprosate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Cisplatin and Vinblastine Versus Paclitaxel and Carboplatin as Sequential Chemotherapy Followed by Radiotherapy in Locally Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Vinblastine Sulfate|RADIATION: three dimensional conformal radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Gastrointestinal Disorder
Interventions: DRUG: Vancomycin|DRUG: MoviPrep|BIOLOGICAL: Full Spectrum Microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women SHARE Study: Reducing Sexual Risk
Status: COMPLETED
Conditions: Alcohol and Substance-Related Mental Disorders|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Brief Intervention (BI) with Technology Extender|OTHER: Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Repeated Treatments With Recombinant Botulinum Toxin Type A for Injection in the Treatment of Moderate to Severe Glabellar Lines
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: Rcombinant botulinum neurotoxin type A for injection (YY001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phentolamine Mesylate as a Reversal of Local Anesthesics
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Phentolamine Mesylate 0.235 MG/ML [OraVerse]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|GENETIC: Genetic Testing for Cancer Risk|PROCEDURE: Liquid Biopsy|PROCEDURE: Magnetic Resonance Imaging of the Whole Body without Contrast|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Lavage of the Uterine Cavity for Diagnosis of Ovarian Cancer
Status: TERMINATED
Conditions: High Grade Ovarian Serous Adenocarcinoma|Stage III Ovarian Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA1 Ovarian Cancer AJCC v8|Stage IIIA2 Ovarian Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8
Interventions: OTHER: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|DEVICE: Lavage|OTHER: Pap Smear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Intermittent Intravenous Boluses of Phenylephrine and Norepinephrine to Prevent Spinal-induced Hypotension in Cesarean Deliveries
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining an Adaptive Approach to Providing Psychosocial Support to Buprenorphine Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Psychosocial support determined by adaptive treatment algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Educational Technology in Improving Adherence Therapy
Status: COMPLETED
Conditions: Medication Nonadherence|Hypertension, Resistant to Conventional Therapy
Interventions: BEHAVIORAL: Experimental: Individual Orientation|BEHAVIORAL: Experimental: VLE for Distance Learning|BEHAVIORAL: Experimental: E-blended Lerarning|OTHER: Conventional Therapy - Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: NB|BEHAVIORAL: CLI|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freezing of Gait Correction and Fall Prevention: Developing a Real-time Somatosensory Stimulation System
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Real-time somatosensory cue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease
Status: RECRUITING
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|Bronchiectasis|Emphysema|Pulmonary Fibrosis|Bronchopulmonary Dysplasia|Alpha 1-Antitrypsin Deficiency|Sarcoidosis, Pulmonary
Interventions: OTHER: Hyperpolarized 129Xe MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of HABIT-ILE on Visuo-spatial Attention of Children With Unilateral CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: HABIT-ILE with prismatic adaptation|BEHAVIORAL: HABIT-ILE without prismatic adaptation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sodium Bicarbonate Supplementation on Intermittent and Intense Task
Status: UNKNOWN
Conditions: Sodium Bicarbonate|Alkalosis, Metabolic|Electromyography|Fatigue
Interventions: DIETARY_SUPPLEMENT: Sodium bicarbonate|DIETARY_SUPPLEMENT: Calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acupuncture for Pain Management During Uterine Aspiration
Status: COMPLETED
Conditions: Pain Acute|Acupuncture
Interventions: DEVICE: SEIRIN® Pyonex™ Acupuncture Needles|PROCEDURE: 12 mm Plasters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders
Status: RECRUITING
Conditions: HCV Infection|Beta Thalassemia Major
Interventions: DRUG: Sofosbuvir and Ledipasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot of Pragmatic Delivery of Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes type1|Diabetes Mellitus, Type 1|Diabetes, Autoimmune|Diabetes Mellitus|Distress, Emotional
Interventions: BEHAVIORAL: ReCharge|BEHAVIORAL: TakeCharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Cholestasis
Interventions: OTHER: CO2 insufflation|OTHER: Room air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Veltuzumab and Milatuzumab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: milatuzumab|BIOLOGICAL: veltuzumab|PROCEDURE: Correlative/Special Studies|PROCEDURE: Quantitative T-, B-, and NK cell subsets|PROCEDURE: Pharmacokinetics|PROCEDURE: Pharmacokinetics|PROCEDURE: Human Anti-Human Antibodies|BIOLOGICAL: veltuzumab and milatuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomics Studies of Antidepressants
Status: UNKNOWN
Conditions: Major Depressive Disorder|Antidepressive Agents|Pharmacogenetics|Venlafaxine|Fluoxetine
Interventions: DRUG: Venlafaxine|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Trunk Block Feasibility by Anesthesia Residents
Status: NOT_YET_RECRUITING
Conditions: Anesthesia, Local|Shoulder Pain
Interventions: PROCEDURE: Interscalene brachial plexus block combined with general anesthesia|PROCEDURE: Upper trunk brachial plexus block combined with general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert
Status: COMPLETED
Conditions: Non-Infectious Uveitis
Interventions: DRUG: FAI insert|DRUG: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Early-Stage Amputation and External Herbs Chitosan for Diabetic Foot Ulcer
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Early-stage amputation|PROCEDURE: Amputation|OTHER: External herbs chitosan|OTHER: Traditional gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of a Health Literacy Intervention in the Workplace
Status: COMPLETED
Conditions: Health Literacy
Interventions: BEHAVIORAL: Motivational/health literacy education (Test group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Indigo Naturalis Oil Extract and Calcipotriol Solution in Treating Psoriasis
Status: COMPLETED
Conditions: Nail Psoriasis
Interventions: DRUG: Indigo Naturalis Extract in Oil|DRUG: Calcipotriol Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Favir 200 mg Film Tablet Kocak Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: FAVIR 200 MG FT|DRUG: AVIGAN 200 mg FT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Osteoporosis and Fall Prevention With Multiple Interventions in the Metropolitan Area
Status: COMPLETED
Conditions: Osteoporosis Fracture
Interventions: BEHAVIORAL: ICG|BEHAVIORAL: MTG|BEHAVIORAL: XBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-Term Study of Atomoxetine in Children With Attention-Deficit/Hyperactivity Disorder (AD/HD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Manual and Neurocognitive Skills-While Sitting, Standing, Walking on a Treadmill and Using a Stepper.
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Sitting workstation|BEHAVIORAL: Standing workstation|BEHAVIORAL: Stepping workstation|BEHAVIORAL: Walking workstation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study
Status: RECRUITING
Conditions: Lung Carcinoma|Lung Non-Small Cell Carcinoma|Metastatic Malignant Neoplasm in the Lung|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Radiology, Treatment Planning|RADIATION: Stereotactic Body Radiation Therapy|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study to Assess the Effect of the Amount of Carbohydrate Intake and Meals Differing in Glycemic Index (GI) in Patients Treated With a Sodium-dependent Glucose Cotransporter 2 (SGLT2) Inhibitor
Status: COMPLETED
Conditions: Diabetes Melltius, Type 2
Interventions: DRUG: Luseogliflozin|OTHER: Meal containing different carbohydrate ratio and GI value
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-site Cohort Study for the Development of Personalized Pharmacotherapy in Patients With Tuberculosis (TB)
Status: RECRUITING
Conditions: Tuberculosis|Latent Tuberculosis|Nontuberculous Mycobacterium Infection
Interventions: PROCEDURE: therapeutic drug monitoring(TDM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-center Prospective Study to Validate the Performance of the Aktiia Optical Blood Pressure Monitoring (OBPM) Device at the Wrist Against Ambulatory Blood Pressure Monitoring (ABPM)
Status: COMPLETED
Conditions: Blood Pressure|Hypertension
Interventions: DEVICE: Aktiia.product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Isoflavones in Treating Women Who Have Breast Cancer and Are Planning to Undergo Mastectomy or Lumpectomy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Soy protein isolate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)
Status: WITHDRAWN
Conditions: Neuroblastoma|Neuroendocrine Tumor
Interventions: DRUG: Retinoic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-prescription Versus Prescription Topical Treatments Versus no Treatment in the Control of Sweating
Status: COMPLETED
Conditions: Hyperhidrosis|Excess Sweating
Interventions: DRUG: Drysol|DRUG: Drioff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of a Newly Formulated Toothpaste in Tooth Staining Associated With Chlorhexidine Rinses
Status: COMPLETED
Conditions: Tooth Staining|Periodontitis
Interventions: OTHER: Toothpaste with hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP)|OTHER: Toothpaste without hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ertapenem Study in Pediatric Patients Who Have Urinary Tract Infections, Skin Infections or Community-acquired Pneumonia (0826-036)
Status: COMPLETED
Conditions: Urinary Tract Infections|Bacterial Pneumonia|Soft Tissue Infections
Interventions: DRUG: MK0826, ertapenem sodium /Duration of Treatment: 14 Days|DRUG: Comparator: ceftriaxone sodium /Duration of Treatment: 14 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Capecitabine|DRUG: Cetuximab|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phase IVb of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Children
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease (HFMD)
Interventions: BIOLOGICAL: inactivated EV71 vaccine (KMB-17 cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Community-based Clinical Trial With Microbiota Directed Complementary Foods (MDCFs) Made of Locally Available Food Ingredients for the Management of Children With Post-severe Acute Malnutrition Moderate Acute Malnutrition (Post-SAM MAM)
Status: UNKNOWN
Conditions: Microbiota|Complementary Food|Nutrition
Interventions: DIETARY_SUPPLEMENT: Microbiota Directed Complementary Food-2|DIETARY_SUPPLEMENT: Ready to Use Supplementary Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deferasirox on Endocrine Complications in Subjects With Transfusion Dependent Thalassemia
Status: WITHDRAWN
Conditions: Thalassemia (Transfusion Delendent)
Interventions: DRUG: deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First-in-Human Study of AV-001 in Healthy Subjects
Status: COMPLETED
Conditions: Covid19-associated ARDS|Covid19|ARDS
Interventions: DRUG: AV-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LabAlert: Enhancing Medication Safety Through Electronic Interventions to Improve Laboratory Monitoring
Status: COMPLETED
Conditions: Safety
Interventions: DEVICE: Electronic Medical Record (EMR) to clinician's in-basket|DEVICE: Automated Voice Message (AVM) reminder to patient's phone|PROCEDURE: Pharmacy Team phone call-letter followup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Mosunetuzumab (IV)|DRUG: Tocilizumab|DRUG: Lenalidomide|DRUG: Mosunetuzumab (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid Surgery
Status: COMPLETED
Conditions: Primary Hyperparathyroidism|Thyroid Disease|Parathyroid Diseases|Parathyroid Adenoma
Interventions: PROCEDURE: Conventional (dual-phase) SPECT/CT|PROCEDURE: Multi-phase SPECT/CT|PROCEDURE: Conventional minimally-invasive radio-guided parathyroidectomy|PROCEDURE: Individualised minimally-invasive radio-guided parathyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Monthly Long-acting IM Injection of 80 or 40 mg GA Depot in Subjects With RRMS
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: GA Depot 80 mg|DRUG: GA Depot 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study With Silymarin in the Patients With Chronic Hepatitis C Infection Who Failed Conventional Antiviral Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Silymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: His-pacing and AV-node Ablation vs. Pulmonary Vein Isolation for Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Dilatation
Interventions: PROCEDURE: Conduction System pacing and AV node ablation|PROCEDURE: Atrial fibrillation ablation by pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of KHK2375 in Subjects With Advanced or Recurrent Breast Cancer
Status: COMPLETED
Conditions: Advanced or Recurrent Breast Cancer
Interventions: DRUG: Entinostat|DRUG: Entinostat(Placebo)|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Pain Sample)
Status: COMPLETED
Conditions: Pain, Intractable|Pain, Chronic
Interventions: OTHER: Meditation (1 x 20-minute guided audio training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of CX-3543 in Patients With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoma
Interventions: DRUG: CX-3543
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Responses to Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Adults
Status: COMPLETED
Conditions: Exposure to Pollution
Interventions: OTHER: Clean Air|OTHER: PM2.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Health Action Process Approach and Movement Patterns in Adult Office Workers
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: HAPA SB Intervention Slideshow|BEHAVIORAL: HAPA MVPA Attention-Control Slideshow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of N&H Sandwich Technique and Cesarean Hysterectomy in Management of Placenta Accreta Spectrum
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: cesarean hysterectomy|PROCEDURE: N&H sandwich technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Detection of Subclinical Cerebral Suffering Related to Hypertension Using Multimodal MRI
Status: RECRUITING
Conditions: Hypertension
Interventions: DIAGNOSTIC_TEST: multimodal magnetic resonance imaging|DIAGNOSTIC_TEST: blood test|DIAGNOSTIC_TEST: neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Osteopathic Manipulative Treatment in Oncology Patients' Management
Status: COMPLETED
Conditions: Geriatric Oncology|Osteopathy in Other Diseases Classified Elsewhere
Interventions: OTHER: Osteopathic manipulative treatment|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Peppermint Oil Inhalation on Postoperative Nausea, Vomiting and Comfort
Status: NOT_YET_RECRUITING
Conditions: Inhalation; Oil
Interventions: OTHER: Peppermint Oil Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds
Status: TERMINATED
Conditions: Invasive Fungal Infections
Interventions: DRUG: fosmanogepix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction, Efficacy and Compliance of Antiemetic Patch vs Pill in Malignant Glioma Patients
Status: WITHDRAWN
Conditions: Malignant Glioma
Interventions: DRUG: Granisetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study to Assess Activity & Safety of Front-line Ibrutinib + Rituximab in Unfit Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocyte Leukemia|Adult Patients
Interventions: DRUG: Ibrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: RC18 240 mg|BIOLOGICAL: RC18 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Telerehabilitation Based Pilates Training in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Telerehabilitation-based Pilates Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Microelectrolysis on Myofascial Trigger Points Pain.
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain (MTrP)
Interventions: DEVICE: Percutaneous microelectrolysis|DEVICE: Ultrasound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: VBR|DRUG: AB-729|DRUG: SOC NrtI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiemetic Prophylaxis With Fosaprepitant and Ondansetron in Patients Undergoing Thoracic Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Nausea and Vomiting|Anesthesia Complication|Thoracic Diseases
Interventions: DRUG: Ondansetron 8mg|DRUG: Fosaprepitant 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults
Status: COMPLETED
Conditions: Infections
Interventions: DRUG: Cefazolin 3gm for Injection USP and Dextrose Injection USP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Effect of Topical Anesthesia During Induction in Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Valvular Heart Disease|Arrythmia
Interventions: PROCEDURE: The combined topical anesthesia induction group|PROCEDURE: The routine induction group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Drug Drug Interactions of Aspirin and P2Y12-inhibitors
Status: COMPLETED
Conditions: Drug Interaction Potentiation|Myocardial Infarction
Interventions: DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of NPWT in Reducing the Incidence of Wound Infection After Pancreatic Surgery
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DEVICE: Disposable negative wound pressure device (PICO)|DEVICE: OPsite post-op visible standard sterile dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture and Mindfulness Based Stress Reduction for Wellness
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|PROCEDURE: Acupuncture Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine vs Povidone Iodine Vaginal Prep in Decreasing Postoperative Infection in Total Laparoscopic Hysterectomy
Status: WITHDRAWN
Conditions: Preventative Laparoscopic Hysterectomy
Interventions: DIAGNOSTIC_TEST: A vaginal swab for aerobic and anaerobic cultures before antibiotic administration, 30 minutes after vaginal prep and every hour thereafter until the surgery is completed.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biological & Fonctional Signatures for Muscle Failures, Aged People & Personalized Physical Activity
Status: RECRUITING
Conditions: Elderly
Interventions: PROCEDURE: blood sample|OTHER: physical assessement|BEHAVIORAL: psychometric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pairing Functional Electrical Stimulation (FES) and Volitional Effort Training Promotes Neuroplasticity and Motor Gain
Status: UNKNOWN
Conditions: Stroke|Drop Foot
Interventions: OTHER: FES + VOL|OTHER: FES|OTHER: VOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation and Surgical Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Circumferential pulmonary vein isolation + linear ablation + bi-atrial mapping + driver ablation|PROCEDURE: Circumferential pulmonary vein isolation + linear ablation + vein of Marshall ethanol infusion|PROCEDURE: Surgical ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant as Antiemetic Prophylaxis in Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Salvage Ovarian FANG™ Vaccine + Carboplatinum
Status: COMPLETED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: BIOLOGICAL: Vigil™ Vaccine|DRUG: Carboplatinum|DRUG: Carboplatinum and Taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Gluteus Maximus Strength Exercise Effectiveness for Improving Dynamic Postural Control in Female Basketball Players
Status: COMPLETED
Conditions: Basketball
Interventions: OTHER: Conventional preventive work out|OTHER: Gluteus maximus strengthening specific program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Clobetasol Propionate Versus Hydrocortisone in Children With Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Hydrocortisone 1%|DRUG: Clobetasol Propionate 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Mass Media Family Planning Campaign on the Uptake of Contraceptive Methods in Burkina Faso
Status: UNKNOWN
Conditions: Contraception|Family Characteristics|Family Size, Desired
Interventions: BEHAVIORAL: Radio Mass Media Family Planning Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of NXN 188 for the Treatment of Migraine With Aura
Status: COMPLETED
Conditions: Migraine With Aura
Interventions: DRUG: NXN-188|DRUG: placebo|DRUG: sumatriptan succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Multidisciplinary Treatment to the Quality of Life of With Functional Movement Disorders
Status: COMPLETED
Conditions: Functional Neurological Disorder|Functional Movement Disorder
Interventions: BEHAVIORAL: Multidisciplinary therapeutic approach (physiotherapy plus cognitive-behavioral therapy)|OTHER: Psychoeducation (Sham intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological First Aid (PFA): RCT Adults Non-intentional Trauma Emergency Room
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Psychoeducation|BEHAVIORAL: Psychological First Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: DRUG: BI 1291583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Attenuated Versus Inactivated Flu Vaccine in Twin Sets
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Live attenuated influenza vaccine (LAIV4)|BIOLOGICAL: Inactivated Influenza Vaccine (IIV4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE