pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Vascular Inflammation|Coronary Atherosclerosis
Interventions: BIOLOGICAL: Adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial
Status: UNKNOWN
Conditions: PostTraumatic Stress Disorder
Interventions: BEHAVIORAL: Basic Body Awareness Therapy|BEHAVIORAL: Psychological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.
Status: RECRUITING
Conditions: Sleep Deprivation|Nutritional Intervention
Interventions: OTHER: Ketogenic Intervention|OTHER: Mediterranean Intervention|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ketone Ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hybrid AbLaTion of Atrial Fibrillation
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation|Atrial Fibrillation, Persistent|Atrial Arrhythmia|Atrial Fibrillation
Interventions: DEVICE: AtriCure EPi-Sense-AF Guided Coagulation System +/- Atriclip|DEVICE: Endocardial Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS and Aphasia Therapy in the Chronic Phase After Stroke
Status: TERMINATED
Conditions: Aphasia Following Cerebral Infarction|Aphasia Following Nontraumatic Intracerebral Hemorrhage
Interventions: PROCEDURE: tDCS|PROCEDURE: Aphasia therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics and Effect on Inflammation of Oral BI 1026706 in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1026706|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Ellume® Respirio Flu Test and the Ellume® eLab Flu Test for the Rapid Identification of Influenza A/B
Status: COMPLETED
Conditions: Influenza A|Influenza B
Interventions: DEVICE: Respirio Flu Test|DEVICE: eLab Flu Test|DEVICE: Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexmedetomidine and Nalbuphine as Analgesic Adjuvants to Bupivacaine in Superficial Cervical Block.
Status: NOT_YET_RECRUITING
Conditions: Anterior Cervical Discectomy and Fusion (ACDF)
Interventions: DRUG: Dexmedetomidine in superficial cervical plexus block|DRUG: Nalbuphine in superficial cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Adalimumab to Treat Interstitial Cystitis
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: Adalimumab|OTHER: inactive drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PVd Versus Vd in NDMM Patients With RI
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|de Novo Myelodysplastic Syndromes|Myelodysplastic Syndrome With Isolated Del(5q)|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Sirolimus|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myelogenous Leukemia|Ovarian Cancer|Colorectal Cancer|Triple-negative Breast Cancer|Small-cell Lung Cancer
Interventions: BIOLOGICAL: galinpepimut-S|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Effectiveness of Vagus Nerve Stimulation for Children With Refractory Epilepsy
Status: UNKNOWN
Conditions: Refractory Epilepsy
Interventions: DEVICE: PINS Vagus Nerve Stimualtor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Pancreatic Cancer|Esophageal Cancer|Gastric Cancer|Rectal Cancer|Liver Cancer|Biliary Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neural Response to Catecholamine Depletion in Subjects Suffering From Bulimia Nervosa in Their Past and Healthy Controls
Status: SUSPENDED
Conditions: Bulimia Nervosa|Eating Disorders|Dopamine|Reward|Catechol-O-methyltransferase
Interventions: DRUG: AMPT/ Demser|DRUG: Diphenhydramine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined taVNS and tDCS in Subacute Stroke Patients
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: tDCS stimulation|DEVICE: taVNS stimulation|DEVICE: sham tDCS stimulation|DEVICE: sham taVNS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm, Thoracoabdominal
Interventions: PROCEDURE: Minimally-Invasive Segmental Artery Coil-Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Altitude on Iron Absorption in Iron Depleted Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Iron Deficiency Anemia|Iron Deficiency (Without Anemia)|Altitude Hypoxia
Interventions: OTHER: Biofortified potato, not genetically modified
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Mirabegron (YM178) in Men With Lower Urinary Tract Symptoms (LUTS) and Bladder Outlet Obstruction (BOO)
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Bladder Outlet Obstruction
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of F2695 on Functional Recovery After Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: F2695|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exparel for Postoperative Pain Management in Shoulder Surgery
Status: COMPLETED
Conditions: Fracture of Shoulder and Upper Arm
Interventions: DRUG: 1.3% Liposomal Bupivacaine|DRUG: 0.125% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Adriamycin, Dexamethasone (RAD) Versus Lenalidomide, Bortezomib, Dexamethasone (VRD) for Induction in Newly Diagnosed Multiple Myeloma Followed by Response-adapted Consolidation and Lenalidomide Maintenance
Status: ACTIVE_NOT_RECRUITING
Conditions: Previously Untreated Symptomatic Multiple Myeloma
Interventions: DRUG: Lenalidomide, Bortezomib|BIOLOGICAL: autologous stem cell transplant|BIOLOGICAL: allogeneic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Respiratory Training in the Prevention and Severity of COVID-19
Status: UNKNOWN
Conditions: Disease, Infectious|Respiratory Disease|Safety Issues|Effectiveness
Interventions: DEVICE: Inspiratory training device|DEVICE: Expiratory training device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Changes Induced by NMN in Healthy Subjects With Acute Binge Drink
Status: ACTIVE_NOT_RECRUITING
Conditions: Binge Drinking|Liver Injury|Nutritional Supplementation|Hepatic Steatosis
Interventions: DIETARY_SUPPLEMENT: β-nicotinamide Mononucleotide|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth|Inadequate Milk Production
Interventions: DRUG: Nicotinamide riboside chloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
Status: ENROLLING_BY_INVITATION
Conditions: Central Post Stroke Pain
Interventions: DEVICE: Stimulation ON|DEVICE: Stimulation Pseudo-ON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Irinotecan/Capecitabine in Patients With Antracycline/Taxane Pretreated MBC
Status: COMPLETED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Irinotecan plus capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PET Study to Determine Biodistribution and Binding Characteristics of [11C]AZ14132516 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [11C]AZ14132516
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Central Venous Catheters With Silver Nanoparticles Versus Conventional Catheters
Status: COMPLETED
Conditions: Central Venous Catheter Related Infections
Interventions: PROCEDURE: CVC impregnated with silver nanoparticles (AgTive®)|PROCEDURE: CVC cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Very Early Versus Delayed Angiography +/- Intervention on Outcomes in Patients With NSTEMI
Status: TERMINATED
Conditions: Cardiovascular; Attack
Interventions: PROCEDURE: Angiography with follow-on revascularisation if indicated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition Effect of the Ankle Manual Therapy to Muscle Strengthening Exercise in Women With Patellofemoral Pain
Status: NOT_YET_RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Warm up|OTHER: Passive calf muscle stretching|OTHER: Ankle joint mobilization - weight-bearing mobilization with movement (WB-MWM) technique|OTHER: Clam exercise|OTHER: Hip abduction exercise in side lying|OTHER: Knee extension exercise in a sitting position|OTHER: Squat exercise|OTHER: Forward lunge exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-cell Approach to Identify Biomarkers of Efficacy and Toxicity for ICI in NSCLC
Status: RECRUITING
Conditions: Lung Diseases, Interstitial|NSCLC|Immunotherapy
Interventions: DRUG: Immune checkpoint inhibitor|DRUG: Chemotherapy + Immune checkpoint inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Microcurrent Therapy for Treatment of Knee Pain
Status: UNKNOWN
Conditions: Acute Knee Pain
Interventions: DEVICE: Microcurrent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)
Status: RECRUITING
Conditions: Advanced Melanoma
Interventions: BIOLOGICAL: IMC-F106C|BIOLOGICAL: Nivolumab|BIOLOGICAL: Nivolumab + Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Illness|Acute Kidney Injury|Sepsis|Systemic Inflammatory Response Syndrome
Interventions: DEVICE: oXiris
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy
Status: COMPLETED
Conditions: Depression|Postpartum Depression|Antenatal Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pevonedistat in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis
Status: TERMINATED
Conditions: Myelofibroses
Interventions: DRUG: Pevonedistat|DRUG: Ruxolitinib|PROCEDURE: Peripheral blood draw|PROCEDURE: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treat_CCM: Propranolol in Familial Cerebral Cavernous Malformation
Status: COMPLETED
Conditions: Cerebral Cavernous Malformation
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of the Addition of AMD3100 to a G-CSF Mobilization Regimen in Patients With Lymphoma (NHL and HD) and Multiple Myeloma (MM).
Status: COMPLETED
Conditions: Lymphoma|Non Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma
Interventions: DRUG: Plerixafor (AMD3100)|DRUG: Can be any registered nonpegylated form of G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia
Status: COMPLETED
Conditions: Iron Overload|Oxidative Stress|Thalassemia Major
Interventions: DRUG: Omega 3|DRUG: Nigella Sativa Oil|DRUG: Hydroxyurea|DRUG: Honey|DRUG: Deferoxamine|PROCEDURE: blood transfusion session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Type-5 Phosphodiesterase Inhibitors in Primary and Secondary Pulmonary Hypertension
Status: WITHDRAWN
Conditions: Primary and Secondary Pulmonary Hypertension
Interventions: DRUG: type-5 phosphodiesterase Inhibitor (Sildenafil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ideal Deep Venous Thrombosis (DVT) Study
Status: COMPLETED
Conditions: Postthrombotic Syndrome
Interventions: DEVICE: Individually tailored duration of elastic compression therapy|DEVICE: Elastic compression therapy with a standard duration of 24 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Manual Therapy for the Treatment of Migraine.
Status: COMPLETED
Conditions: Migraine
Interventions: OTHER: Manual Therapy based on soft tissues|OTHER: Control group|OTHER: Manual Therapy based on structural techniques|OTHER: Manual Therapy based on soft tissues and structural techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OTO-313 in Subjects With Unilateral Subjective Tinnitus
Status: COMPLETED
Conditions: Subjective Tinnitus
Interventions: DRUG: OTO-313|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Large Loop Excision of the Transformation Zone (LLETZ) With vs Without IntraOperative Application of Lugol's Iodine
Status: RECRUITING
Conditions: Cervical Dysplasia
Interventions: DIAGNOSTIC_TEST: Lugol's iodine test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ilioinguinal Nerve Excision in Open Mesh Repair of Inguinal Hernia,a Randomized Clinical Trial
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Hyposthesia
Interventions: PROCEDURE: elective ilioinguinal nerve excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.
Status: NOT_YET_RECRUITING
Conditions: Waldenström's Macroglobulinemia (WM)
Interventions: DRUG: Zanubrutinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Adding Midazolam Versus Fentanyl to Intrathecal Levobupivacaine in Patients Undergoing Caesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Decitabine/Cedazuridine 35 Mg-100 Mg ORAL TABLET|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial of Intravenous Methylprednisolone With 2 Protocols in Patients With Graves Orbitopathy
Status: NOT_YET_RECRUITING
Conditions: Graves Ophthalmopathy
Interventions: DRUG: methylprednisolone(daily scheme)|DRUG: methylprednisolone(weekly scheme)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Therapy in COVID-19 Patients Given Prone Position
Status: COMPLETED
Conditions: Music Therapy|Anxiety|Respiratory Distress Syndrome|Intensive Care Units|Nursing
Interventions: OTHER: musıc therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SSRIs vs. TCAs for Depression in ALS Patients
Status: COMPLETED
Conditions: Depression|Amyotrophic Lateral Sclerosis
Interventions: DRUG: Tricyclic Antidepressants ("TCA")|DRUG: Selective Serotonin Uptake Inhibitors ("SSRI")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Storytelling for Reducing Gap in Anticoagulation Use in African Americans With Atrial Fibrillation
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation|Atrial Flutter|Adherence, Medication|Anticoagulants and Bleeding Disorders|Stroke|Bleeding|Narration
Interventions: BEHAVIORAL: Storytelling Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Solvents Used With Chemotherapy Agent for Transarterial Chemoembolization of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Solvent with specific gravity less than lipiodol|OTHER: Solvent with specific gravity equivalent to lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Hypertension Control in CHina and ARGEntina With a Mobile APP-based Telecare System
Status: RECRUITING
Conditions: Hypertension,Essential|Hypertension, Uncontrolled
Interventions: OTHER: Usual care|OTHER: POST-strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Participants With Cystic Fibrosis Who Have an F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EGFR-TKI Combined With Concurrent or Sequential Chemotherapy for Patients of Gradual Progression
Status: COMPLETED
Conditions: Lung Adenocarcinoma|EGFR Activating Mutation
Interventions: DRUG: icotinib combined with pemetrexed plus cisplatin|DRUG: first icotinib and then pemetrexed plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 and Folic Acid Supplementation for Preventing Fractures in Elderly People
Status: UNKNOWN
Conditions: Osteoporosis|Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Vitamin B12, folic acid, Vitamin D3|DIETARY_SUPPLEMENT: Placebo (Vitamin D3) - 600 IU per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vascular Effect of Estradiol Valerate Versus Placebo Evaluated by Flow-mediated Dilatation of Brachial Artery
Status: COMPLETED
Conditions: Flow-mediated Dilation Evaluation of the Brachial Artery
Interventions: DRUG: Estradiol valerate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Multicenter, Randomized, Controlled Study of IM or Oral Exemestane (Aromasin) in Postmenopausal Women
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Determination of Cerebral Tissue Oxygenation in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Right heart catheterization|PROCEDURE: Near-infrared spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: DRUG: Colchicine 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging During Surgery in Diagnosing Patients With Prostate, Bladder, or Kidney Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer|Kidney Tumor|Prostate Cancer
Interventions: PROCEDURE: photoacoustic imaging|PROCEDURE: fluorescence imaging|PROCEDURE: robot-assisted laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ocular Micro-vascular Research Base on Functional Slip Lamp Biomicroscopy
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Inflammation|Microvessels
Interventions: DRUG: Fluorometholone|DEVICE: Functional Slit-Lamp Biomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Preference Comparison of AZARGA Versus COSOPT
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1.0% + Timolol 0.5% ophthalmic suspension|DRUG: Dorzolamide 2.0% + Timolol 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Early Association of Terlipressin and Norepinephrine During Septic Shock; the TerliNor Study
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Terlipressin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravaginal Misoprostol Versus Dinoprostone Before Diagnostik Hysteroscopy
Status: UNKNOWN
Conditions: Cervical Ripening
Interventions: DRUG: Dinoprostone|DRUG: misoprostol|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cladribine and Low-Dose Cytarabine (LoDAC) Alternating With Decitabine vs. Hypomethylating Agents (HMA) Plus Venetoclax as Frontline Therapy for AML or High-Grade MDS in Patients Unfit for Intensive Induction
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Decitabine|DRUG: azacitidine or decitabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared-Decision Making for Hydroxyurea
Status: UNKNOWN
Conditions: Sickle Cell Anemia|Children, Only
Interventions: BEHAVIORAL: Hydroxyurea SDM Toolkit|BEHAVIORAL: Clinician Pocket Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of a Cell Derived Subunit Trivalent Nonadjuvated Influenza Study Vaccine in Adults Aged 18 Years and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell derived subunit trivalent nonadjuvanted vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Criteria Based Clinical Pathway for Rehabilitation of Shoulder Injuries
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain|Shoulder Injuries
Interventions: OTHER: CRISP: Criteria-Based Approach for the Rehabilitation for Non-Operative Shoulder Injuries|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation
Status: UNKNOWN
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: Dynamic Annuloplasty Ring (with option to adjust off-pump)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Tipranavir and Ritonavir in Multiple Protease Inhibitor-experienced HIV Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tipranavir low dose|DRUG: Tipranavir high dose|DRUG: Ritonavir|DRUG: Nucleoside Reverse Transcriptase Inhibitor (NRTI)|DRUG: Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linked Color Imaging Based CMV Diagnosis for Gastric Mucosal Lesions
Status: UNKNOWN
Conditions: Gastric Disease
Interventions: PROCEDURE: WLE and then LCI|PROCEDURE: LCI and then WLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Chemotherapy With/Without Toripalimab For Primary Metastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Toripalimab|RADIATION: IMRT to the nasopharynx and neck|DRUG: Gemcitabine and Cisplatin Chemotherapy|DRUG: Adjuvant chemotherapy with Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of COVID-19
Status: RECRUITING
Conditions: COVID-19|SAR-CoV-2
Interventions: DRUG: (R)-1-(2-chlorophenyl)- N-[11C] ([11C] PK11195)|DRUG: 2-(4-[11C]methylamino phenyl)-6-hydroxybenzothiazole (11C]6-OH-BTA-1 or [11C]PIB)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Topical Phenytoin in Bisphosphonate-related Osteonecrosis of the Mandible
Status: COMPLETED
Conditions: Osteonecrosis Due to Drugs, Jaw
Interventions: DRUG: Topical Phenytoin 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety of Bio Farma's Measles-Rubella (MR) Vaccine in Indonesian Infants (Bridging Study)
Status: COMPLETED
Conditions: Congenital Rubella Infection|Measles
Interventions: BIOLOGICAL: Measles-Rubella vaccine Bio Farma|BIOLOGICAL: MR Vaccine SII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Dovitinib and Biomarkers in Advanced Non-Small Cell Lung Cancer or Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Colorectal Cancer
Interventions: DRUG: Dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Quinine Sulfate Capsules 324mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Quinine Sulfate 2 x 324 mg Capsules|DRUG: Quinine Sulfate 2 x 324 mg Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Outcome and Effectiveness Between Micropulse Diode Laser Cyclophotocoagulation and Cyclocryoablation in Treatment of Refractory Glaucoma
Status: UNKNOWN
Conditions: Treatment of Refractory Glaucoma
Interventions: PROCEDURE: Micropulse diode laser cyclophotocoagulation in treatment of refractory Glaucoma|PROCEDURE: Cyclocryoablation in treatment of refractory Glaucoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Nerve Block for Headache Tx360
Status: COMPLETED
Conditions: Headache|Migraine
Interventions: DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pharmacist-Initiated Home Blood Pressure Monitoring on Blood Pressure Control in Women
Status: RECRUITING
Conditions: Hypertension
Interventions: DEVICE: Home blood pressure monitor|PROCEDURE: Enhanced community pharmacist care|PROCEDURE: Usual pharmacist care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Patient Motivation and Participation in Rehabilitation Program Through Social Games
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: traditional wooden checkerboard|OTHER: gaming board with single-player games|OTHER: gaming board with two-player games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intake of a Polysaccharides Mix on Metabolism, Hormones and Satiety in Obese Children.
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: Libramed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pyrotinib, Trastuzumab, Pertuzumab and Nab-paclitaxel as Neoadjuvant Therapy in HER2-positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Invasive
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Nab-paclitaxel|DRUG: EC chemotherapy|DRUG: Physician's choice|DRUG: T-DM1|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Image the Esophagus Using a SECM Tethered Endoscopic Capsule
Status: COMPLETED
Conditions: Healthy|Barrett's Esophagus|Gastric Acid Reflux
Interventions: DEVICE: MGH SECM Imaging Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Efficacy and Tolerability of 12-weeks Treatment With Almond and Buckwheat Based Formula in Pediatric Patients With Active EoE
Status: RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DIETARY_SUPPLEMENT: Else nutrition formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation
Status: TERMINATED
Conditions: Dilated Cardiomyopathy|Lamin A/C Gene Mutation
Interventions: DRUG: ARRY-371797 (PF-07265803)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance, Pharmacokinetics and Activity of HE3286 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: HE3286|DRUG: HE3286|DRUG: HE3286
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Comprehensive Respiratory Physiotherapy in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: OTHER: Comprehensive Respiratory Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electrodiagnostic Testing
Status: COMPLETED
Conditions: Pain Perception
Interventions: DRUG: EMLA Cream|DRUG: Ibuprofen|DRUG: Placebo syrup|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Carriage
Interventions: BIOLOGICAL: PCV10 full dose|BIOLOGICAL: PCV10 fractional dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EverLift in the Performance of Polypectomy for Polyps 4-9mm
Status: COMPLETED
Conditions: Colo-rectal Cancer|Polyp of Colon|Adenomatous Polyp of Colon
Interventions: DEVICE: Use of EverLift|DEVICE: Without use of EverLift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery
Status: UNKNOWN
Conditions: Colon Neoplasms|Rectal Neoplasms|Inflammatory Bowel Disease|Diverticular Disease
Interventions: PROCEDURE: Near-infrared ICG fluorescence imaging|PROCEDURE: Traditional bowel anastomosis|DEVICE: FireFly™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Methods to Achieve Tight Glucose Control in Cardiovascular ICU Patients
Status: COMPLETED
Conditions: Hyperglycemia in Critically Ill Patients
Interventions: BEHAVIORAL: Nursing judgement|BEHAVIORAL: Nomogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Effects of CAL-101 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: CAL-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Surgical Treatment of Type 2 Diabetes Mellitus in Non-Morbidly Obese Patients: A Community Hospital Study
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Laparoscopic duodenal exclusion|OTHER: Conventional Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of CD19-targeted Chimeric Antigen Receptor T Cells(BZ019) for Relapsed and Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Transformed Lymphoma|Primary Mediastinal Large B Cell Lymphoma
Interventions: BIOLOGICAL: BZ019
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Pharmacokinetic Study of E3710 Following Oral Administration to Healthy, Male, Japanese Subjects
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: E3710|DRUG: E3710
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation Defects
Status: RECRUITING
Conditions: Periodontal Diseases|Periodontal Disease, AVDC Stage 3|Periodontal Disease, AVDC Stage 4|Furcation Defects
Interventions: OTHER: Emdogain® FL (flapless Emdogain®) - Enamel Matrix Derivative|OTHER: Emdogain® - Enamel Matrix Derivative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Biofer ® Compound Used in Blédilait Follow on Milk in Infant With Latent Iron Deficiency
Status: SUSPENDED
Conditions: Latent Iron Deficiency
Interventions: DRUG: Bledilait Biofer®|DRUG: Milk supplemented with ferrous sulphate|DRUG: Blédilait Biofer®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physiological and Psychological Effects of Virtual Reality vs Traditional Exercise
Status: COMPLETED
Conditions: Healthy|Physical Activity|Virtual Reality|Exergame|Inactivity, Physical
Interventions: OTHER: Virtual Reality|OTHER: Traditional HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Double-Blind Placebo-Controlled Crab or Shrimp Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques
Status: UNKNOWN
Conditions: Food Allergies
Interventions: PROCEDURE: NAET|PROCEDURE: NAET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrauterine Injection of HCG on Clinical Pregnancy Outcome in Repeated Implantation Failure Patients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: HCG|OTHER: culture medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial)
Status: RECRUITING
Conditions: Critical Illness|ICU Acquired Weakness|Malnutrition
Interventions: OTHER: Optimisation of nutrition therapy coupled with early mobilisation|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography in Rheumatoid Arthritis With Adalimumab (PETRA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Expulsive Therapy for Ureter Stone Using Naftopidil
Status: COMPLETED
Conditions: Ureter Stones
Interventions: DRUG: Naftopidil 75mg|DRUG: Placebo for Naftopidil|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE-FS
Status: RECRUITING
Conditions: Rheumatic Diseases|Pain, Chronic
Interventions: BEHAVIORAL: Cognitive behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Vemurafenib + Cobimetinib on Immunity in Patients With Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Indo-SURFT in Reducing Addictive Substance Use in Women With Substance Use Disorders
Status: NOT_YET_RECRUITING
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Indonesia Substance Use Reduction for Female Therapy (Indo-SURFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression
Status: COMPLETED
Conditions: Dietary Modification|Kidney Diseases, Chronic
Interventions: BEHAVIORAL: Usual protein and phosphorus diet|BEHAVIORAL: Low protein and phosphorus diet|BEHAVIORAL: Very low protein and phosphorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION