pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pressure Sore Prevention Strategy for the Prone Position
Status: NOT_YET_RECRUITING
Conditions: Pressure Ulcers Prevention in Prone Positioning in Intensive Care
Interventions: OTHER: Hydrocellular dressing|OTHER: Hydrocolloids dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Balanced Crystalloid vs. Saline in Children With Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Shock
Interventions: DRUG: Balanced crystalloid solution|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine A) for the Treatment of Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Restasis, Optive Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Infection|Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: GENETIC: polymerase chain reaction|OTHER: bronchoalveolar lavage|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|PROCEDURE: bronchoscopy|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Dexamethasone to Increase the Analgesic Duration of Interscalene Block
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexamethasone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: BIOLOGICAL: ZG006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study: 2 mg Estradiol Valerate (EV) and 3 mg Dienogest (DNG) Without and With Levomefolate Calcium
Status: COMPLETED
Conditions: Pharmacology, Clinical
Interventions: DRUG: BAY 98-7079, Estradiolvalerate (EV) / Dienogest (DNG) / Levomefolate calcium|DRUG: BAY 86-5027,Estradiolvalerate(EV) / Dienogest (DNG)|DRUG: BAY 86-7660,levomefolate calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Tolerability of Asenapine With Flexible Dosing From 5mg to 20mg in Adults With Developmental Stuttering
Status: SUSPENDED
Conditions: Stuttering
Interventions: DRUG: Asenapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use Cessation
Interventions: DRUG: Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler|DRUG: Varenicline or bupropion|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Mindfulness Program to Reduce Stress and Burnout in Professionals of Medicine and Nursing (MINDUUDD)
Status: COMPLETED
Conditions: Stress|Burnout Syndrome
Interventions: BEHAVIORAL: Mindfulness and Mindful Self-Compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Variability of Hepatic Load Quantification in Iron and Fat Estimated by MRI at 1.5 and 3 Tesla
Status: COMPLETED
Conditions: Iron Hepatic Overload|Fat Hepatic Overload
Interventions: DEVICE: 1,5 Tesla abdominal MRI|DEVICE: 3 Tesla abdominal MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FID-007 Followed by Standard of Care Surgery in Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: PEOX-based Polymer Encapsulated Paclitaxel FID-007|PROCEDURE: Tumor Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: alemtuzumab|DRUG: methylprednisolone|DRUG: prednisone|OTHER: flow cytometry|OTHER: immunologic technique|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Epacadostat (INCB024360) Alone and In Combination With Pembrolizumab (MK-3475) With Chemotherapy and Pembrolizumab Without Chemotherapy in Participants With Advanced Solid Tumors (MK-3475-434)
Status: COMPLETED
Conditions: Neoplasms|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Epacadostat 25 mg|DRUG: Epacadostat 100 mg|BIOLOGICAL: pembrolizumab 200 mg|DRUG: Cisplatin 75 mg/m^2|DRUG: Carboplatin Area Under the Curve (AUC) 5|DRUG: Pemetrexed 500 mg/m^2|DRUG: Paclitaxel 200 mg/m^2|DRUG: Carboplatin AUC 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpoints (Core and Extension Phases)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing Treatment
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Atrial Fibrillation, Persistent|Sick Sinus Syndrome|Atrioventricular Block
Interventions: PROCEDURE: Right heart catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Honey as A Wound Care Modality in Treating Deep Neck Space Abscess
Status: RECRUITING
Conditions: Neck Abscess
Interventions: OTHER: Honey|OTHER: PHMB Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic and Insulinaemic Responses After Consumption of FOS.
Status: COMPLETED
Conditions: Glycaemia
Interventions: OTHER: Sugar|OTHER: FOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Medical Hypnosis and Music for Palliative Care
Status: RECRUITING
Conditions: Palliative Care|Pain Management|Anxiety|Well-being
Interventions: BEHAVIORAL: Personalized multimodal intervention involving hypnosis and/or music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Contribution Of Cognitivo-Behavorial Therapy In Shoulder Apprehension
Status: RECRUITING
Conditions: Shoulder Dislocation|Shoulder Instability
Interventions: OTHER: Rehabilitation physiotherapy|OTHER: Cognitive-behavioral therapies in addition to rehabilitation physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Landmark vs. Ultrasound-Assisted Bone Marrow Biopsy Procedure Study
Status: RECRUITING
Conditions: Bone Marrow Biopsy Procedure
Interventions: DEVICE: Ultrasound-assisted bone marrow biopsy|PROCEDURE: Landmark palpation bone marrow biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Apatinib Combined With Vinorelbine for Non-driver Gene Mutation Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Apatinib Combined With Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 99Tc-MDP in Postmenopausal Women With Differentiated Thyroid Cancer and Osteoporosis
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer|Osteoporosis
Interventions: DRUG: 99Tc-MDP|DRUG: Fosamax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC
Status: RECRUITING
Conditions: Lung Cancer|Extensive-stage Small-cell Lung Cancer
Interventions: RADIATION: Low-dose radiotherapy|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Sugemalimab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
Status: UNKNOWN
Conditions: Obesity|PreDiabetes|Diabetes|Hypertension|NAFLD|Metabolic Syndrome|Dyslipidemias|Inflammation|Gout|Cardiometabolic Syndrome|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Intermittent Fasting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Functional Bowel Disorders
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Constipation|Abdominal Pain|Functional Colonic Diseases
Interventions: DRUG: Desipramine|BEHAVIORAL: Cognitive Behavioral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations
Status: TERMINATED
Conditions: ACL Repair|Meniscectomy|Bankart Repair
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bulk Versus Fractionated Stem Cell Infusions in Patients With Hematologic Malignancies Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Leukemia
Interventions: PROCEDURE: allogeneic hematopoietic stem cell transplantation|DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics
Status: RECRUITING
Conditions: Sodium Excess
Interventions: DIETARY_SUPPLEMENT: High Sodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency
Status: UNKNOWN
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Polyglucoferron|DRUG: Ferric carboxymaltose|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Sapanisertib in Combination With Exemestane or Fulvestrant in Postmenopausal Women With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Sapanisertib|DRUG: Fulvestrant|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detecting Post-surgical Respiratory Compromise and Prompting Patients to Self-rescue: An Early Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia
Interventions: DEVICE: NM3, Phillips Medical, Wallingford CT: verbal prompts to breathe with an optional shoulder shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: Colon Cancer|Colorectal Cancer|Gastrointestinal Cancer|Metastatic Colorectal Cancer|Rectal Cancer
Interventions: DRUG: Panitumumab|DRUG: Ganitumab|DRUG: Rilotumumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Tolerance & Health Effects of Daily Consumption of Two Eggs With Fatty Acid Profile Related to Metabolic Disorders
Status: COMPLETED
Conditions: Healthy|Abdominal Obesity|Sedentary Behavior
Interventions: OTHER: Eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: DMMR Colorectal Cancer|MSI-H Colorectal Cancer|Locally Advanced Colorectal Cancer
Interventions: DRUG: PD-1 Antibody|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: External beam radiotherapy|PROCEDURE: Total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and Obesity
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity|Functional Hypogonadism
Interventions: DRUG: Semaglutide|DRUG: Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating the Relative Bioavailability of SHR7280 Dry Suspension and Tablets
Status: COMPLETED
Conditions: Endometriosis, Uterine Fibroids, Male Hormone-sensitive Prostate Cancer, Assisted Reproduction
Interventions: DRUG: SHR7280 tablets|DRUG: SHR7280 dry suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation Between Optic Nerve Vessel Anomalies, Serum Angiogenic Factors and Renal Anomalies in Down Syndrome Children
Status: UNKNOWN
Conditions: Down Syndrome
Interventions: DIAGNOSTIC_TEST: Funduscopic examination and retinal photography|DIAGNOSTIC_TEST: Serum levels of endostatin and angiogenesis factors|DIAGNOSTIC_TEST: Renal and low urinary tract Doppler ultrasound|DIAGNOSTIC_TEST: Urinalysis|DIAGNOSTIC_TEST: Anthropometric measures and vitals signs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RO6958688 in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen Positive Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: RO6958688|DRUG: Obinutuzumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia Derived HIV-1 Recombinant Envelope Glycoprotein (gp160) of Human Immunodeficiency Virus: Evaluation of Accelerated Schedules
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (Immuno-AG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effects of Intensive Antiplatelet Therapy for Patients With Clopidogrel Resistance After Coronary Stent Implantation
Status: COMPLETED
Conditions: Acute Coronary Syndromes|Percutaneous Coronary Intervention|Clopidogrel Low Responsiveness
Interventions: DRUG: aspirin, clopidogrel|DRUG: aspirin, clopidogrel, cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of BMN 111 to Evaluate Safety, Tolerability, and Efficacy in Children With Achondroplasia
Status: COMPLETED
Conditions: Achondroplasia
Interventions: DRUG: BMN 111
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversing Type 1 Diabetes After it is Established
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Anti-Thymocyte Globin (ATG)|DRUG: Placebo|DRUG: Pegylated GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Leadless Pacing on Heart Function
Status: COMPLETED
Conditions: Pacing-Induced Cardiomyopathy
Interventions: DEVICE: Micra Transcatheter Pacing System (TPS°|DEVICE: Conventional pacemaker type Medtronic Advisa ADSR03 or Azure XT VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Single Dose Dexamethasone in Reducing the Postembolization Syndrome in Men Undergoing Prostatic Artery Embolization for Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Advanced Extubation Techniques in Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Extubation
Interventions: DEVICE: 14F staged extubation set guidewire|DEVICE: Tube changing catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Randomized Clinical Trial
Status: RECRUITING
Conditions: High Myopia
Interventions: DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Validity of Extracorporeal Fenestration and in Situ Fenestration in Patients With Aortic Disease Involving the Left Subclavian Artery
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection Aneurysm
Interventions: PROCEDURE: fenestration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Labcorp COVID-19+Flu+RSV Test Home Collection Kit
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection|Influenza A|Influenza Type B|RSV Infection
Interventions: DEVICE: Labcorp COVID-19+Flu+RSV Test Home Collection Kit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effects of Oral Contraceptive Pills Versus Metformin
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: OCP + Metformin|DRUG: OCP + Placebo|DRUG: Metformin + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep rTMS for Treatment-Resistant Late-life Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Brainsway H1-Coil Deep TMS System (Sham treatment)|DEVICE: Brainsway H1-Coil Deep TMS System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma|Stage III Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: CXCR2-transduced Autologous Tumor Infiltrating Lymphocytes|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: NGFR-transduced Autologous T Lymphocytes|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VELCADEXA: Velcade and Dexamethasone in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade/Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Hysterectomized Postmenopausal Women
Status: TERMINATED
Conditions: Menopause
Interventions: DRUG: esterified estrogens 1.25mg and methyltestosterone 2.5mg|DRUG: Esterified estrogens 1.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Study on the Quality of Life in Cervical Cancer Patients
Status: UNKNOWN
Conditions: Quality of Life|Cervical Cancer|Urodynamics|Rectum Dynamics|Sex Dysfunction|Pelvic Floor Disorders|Ovarian Reserve Function|Survivorship|Disease-free Survival|Overall Survival
Interventions: DIAGNOSTIC_TEST: questionnaires survey|DIAGNOSTIC_TEST: Urodynamic testing|DIAGNOSTIC_TEST: Rectum dynamics testing|DIAGNOSTIC_TEST: ovarian reserve function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardamom and Topical Roseomonas in Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis|Eczema
Interventions: DRUG: Roseomonas mucosa (RSM2015) and Cardamom seeds|DRUG: Placebo (sucrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions
Status: UNKNOWN
Conditions: Mild Dysplasia of Esophagus|Moderate Dysplasia of Esophagus|Severe Dysplasia of Esophagus|Carcinoma in Situ of Esophagus|Esophageal Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Endoscopic examination using white light, NBI and iodine staining
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)
Status: COMPLETED
Conditions: COVID|Severe Acute Respiratory Syndrome|Sars-CoV2|Acute Kidney Injury|Acute Respiratory Distress Syndrome
Interventions: DRUG: LSALT peptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF)
Status: TERMINATED
Conditions: Premature Ovarian Failure
Interventions: DIETARY_SUPPLEMENT: Dehydroepiandrosterone|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression
Status: COMPLETED
Conditions: Depression|Major Depressive Disorder|Unipolar Depression
Interventions: DRUG: Wellbutrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DFDBA and Xenograft (Cerabone)TM With Decortication in Intrabony Defects
Status: COMPLETED
Conditions: Periodontal Intrabony Defects
Interventions: PROCEDURE: Decortication + bone grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcranial NIR Light Upon Memory
Status: COMPLETED
Conditions: Age-related Cognitive Decline
Interventions: DEVICE: NIR Transcranial phototherapy device|DEVICE: Placebo Transcranial Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy and the Safety of M518101 in Plaque Psoriasis Patients
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: M518101|DRUG: placebo|DRUG: Dovonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Overload Progressive in the Treatment of Shoulder
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Strengthening protocol with progressive load|OTHER: Strengthening protocol without progressive load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 177Lutetium-DOTA-Octreotate Therapy in Somatostatin Receptor-Expressing Neuroendocrine Neoplasms
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Early Intervention Program Applied To Premature Infants
Status: COMPLETED
Conditions: Infant Development|Patient Comfort|Nursing Caries|Premature Infant Disease
Interventions: BEHAVIORAL: supported with the developmental support program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication
Status: TERMINATED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Low Dose CNI Compared With MMF and Full CNI Dose in Heart Transplanted Patients: One Year Follow up
Status: COMPLETED
Conditions: Chronic Rejection of Cardiac Transplant
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Periodontal and Cardiometabolic Responses to Vitamin D Intervention in African Americans With Periodontal Disease
Status: UNKNOWN
Conditions: Periodontal Disease|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Interaction Between Oxytocin and Serotonin
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: oxytocin nasal spray|DRUG: ATD treatment|DRUG: intranasal placebo treatment (placebo-control for oxytocin)|DRUG: oral placebo treatment (placebo-control for ATD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Comfilcon A lens (test)|DEVICE: Omafilcon B lens (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Project RAP: Reaching Adolescents for Prevention
Status: UNKNOWN
Conditions: Alcohol Related Morbidity|Alcohol Dependence
Interventions: BEHAVIORAL: Brief Motivational Intervention|BEHAVIORAL: Assessment and list of resources|BEHAVIORAL: Referral to Community Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of IMO-8400 in Adult Patients With Dermatomyositis
Status: COMPLETED
Conditions: Dermatomyositis
Interventions: DRUG: IMO-8400 Dose Group 1|DRUG: IMO-8400 Dose Group 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
Status: RECRUITING
Conditions: Hypertension|Healthy
Interventions: DEVICE: ViTrack|DEVICE: Oscillometric BP Device|DEVICE: Auscultatory cuff
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism
Status: RECRUITING
Conditions: Hyperaldosteronism|Hypercortisolism|Cushing s Syndrome
Interventions: DRUG: [68Ga]Ga-PentixaFor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating Safety, Tolerability, And Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: ACC-001 + QS-21|BIOLOGICAL: ACC-001|BIOLOGICAL: QS-21|DRUG: Placebo: Phosphate buffered saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteoporotic Precisely Screening Using Chest Radiograph and Artificial Neural Network (OPSCAN)
Status: COMPLETED
Conditions: Osteoporosis|Osteoporotic Fractures
Interventions: OTHER: AI-enabled Chest X-ray-based Screening Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: DEVICE: Nellix System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Intracerebral Hemorrhage|Traumatic Brain Injury
Interventions: DRUG: S-ketamine|OTHER: Isotonic saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition for Precision Health, Powered by the All of Us
Status: RECRUITING
Conditions: Nutrition|Health|Dietary Habits
Interventions: OTHER: Diet A|OTHER: Diet B|OTHER: Diet C|OTHER: Liquid Mixed Meal Tolerance Test|OTHER: Diet-Specific Mixed Meal Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amoxicillin-clavulanate Alone or in Combination With Ciprofloxacin in Low-Risk Febrile Neutropenic Adult Patients: A Prospective, Double-blind, Randomized, Non-Inferiority Multicenter, Phase III Clinical Trial.
Status: WITHDRAWN
Conditions: Febrile Neutropenia
Interventions: DRUG: Placebo|DRUG: Amoxicillin Clavulanate|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Combination Chemotherapy, Filgrastim (G-CSF), and Plerixafor in Treating Patients With Non-Hodgkin Lymphoma Undergoing Mobilization of Autologous Peripheral Blood Stem Cells
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Ifosfamide|PROCEDURE: Leukapheresis|DRUG: Plerixafor|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of PF-06882961 in Chinese Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-06882961|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration Study
Status: RECRUITING
Conditions: Basal Cell Carcinoma|Locally Advanced Basal Cell Carcinoma|Metastatic Basal Cell Carcinoma|Gorlin Syndrome|Basal Cell Nevus Syndrome|Carcinoma, Basal Cell|Carcinoma|Basal Cell Tumor|Skin Cancer|Neoplasm of Skin|Neoplasms, Basal Cell
Interventions: DRUG: Vismodegib|DRUG: Sonidegib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of an Investigational Drug in Human Immunodeficiency Virus (HIV)-Infected Patients Failing Current Antiretroviral Therapies (0518-005)(COMPLETED)
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Comparator: MK0518|DRUG: MK0518|DRUG: MK0518|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Efficacy of an Oral Contraceptive in Treating Acne Papulopustulosa
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Valette|DRUG: Diane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SLC13A5 Deficiency Natural History Study - United States Only
Status: RECRUITING
Conditions: Citrate Transporter Deficiency|Epilepsy|Rare Diseases|Movement Disorders|Genetic Disorder|SLC13A5 Deficiency|EIEE25|Kohlschutter-Tonz Syndrome (Non-ROGDI)|Citrate Transporter Disorder|DEE25
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell)
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Investigational Air-Activated Adhesive-Backed Heat Patch (3-Cell)|OTHER: Temperature Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: H1N1v Vaccination of Pregnant Women: A Longitudinal Cohort Study Characterizing Influenza A H1N1v Vaccination in Pregnant Women
Status: COMPLETED
Conditions: H1N1v Influenza
Interventions: BIOLOGICAL: Focetria|BIOLOGICAL: Focetria|BIOLOGICAL: Focetria|BIOLOGICAL: Focetria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Radiation Therapy in Treating Patients With Liver Metastases
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor
Interventions: RADIATION: stereotactic radiation therapy|PROCEDURE: implanted fiducial-based imaging|PROCEDURE: cone-beam computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety and Pharmacokinetics of CKD-390 Tablet With Viread® Tablet
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: CKD-390|DRUG: Viread® tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children With Uncomplicated Acute Malnutrition
Status: RECRUITING
Conditions: Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: MDF|DIETARY_SUPPLEMENT: RUTF|DIETARY_SUPPLEMENT: RUSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRISPR/Cas9-modified Human T Cell ( PD-1and ACE2 Knockout Engineered T Cells ) for Inducing Long-term Immunity in COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: PD-1 and ACE2 Knockout T Cells|DRUG: PD-1 and ACE2 Knockout T Cells|DRUG: PD-1 and ACE2 Knockout T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Carotid Body Modulation Therapy in Hypertensive Patients by External Ultrasonic Micro-bubble
Status: NOT_YET_RECRUITING
Conditions: Primary Hypertension
Interventions: DEVICE: External Ultrasonic Micro-bubble
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab in Primary Antiphospholipid Syndrome
Status: RECRUITING
Conditions: Autoimmune Disorders
Interventions: BIOLOGICAL: Daratumumab|BIOLOGICAL: Daratumumab|BIOLOGICAL: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study to Evaluate the Blood Kinetics of Immune Cells and Immunosuppressive Cytokines After Exposure to an Immunity Checkpoint Inhibitor (ICI): Study of the Impact of Chemotherapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Bladder Cancer|ENT Cancer
Interventions: OTHER: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Biopsied and Non-biopsied Intracytoplasmatic Sperm Injection (ICSI) Embryos and Natural Pregnancy Embryos
Status: RECRUITING
Conditions: Women Conceiving by: 1- ICSI-PGS 2- ICSI-non-PGS 3- Spontaneously Conceiving Women
Interventions: PROCEDURE: Biopsied ICSI embryos (PGS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Investigation of Acute Effects of Action Observation Training on Upper Extremity Functionality, Reaction Time and Cognitive Functions in Right-handed Healthy Subjects
Status: COMPLETED
Conditions: Right-handed Healthy Adults
Interventions: OTHER: Action observation Training|OTHER: Action Practice|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JHL1101 Versus MabThera® in Subjects With Severe Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Arthritis, Rheumatoid
Interventions: BIOLOGICAL: JHL1101|BIOLOGICAL: MabThera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Anti-PD-1 Plus Lenalidomide and Azacitidine in Relapsed/Refractory Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Peripheral T-cell Lymphoma
Interventions: DRUG: Anti-PD-1 monoclonal antibody|DRUG: Lenalidomide|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PITCHER (Peritoneal Carcinomatosis Heterogeneity)
Status: RECRUITING
Conditions: Secondary Peritoneal Cancers|Colorectal Cancer|Ovarian Cancer
Interventions: OTHER: construction of a database of genetic and epigenetic data on peritoneal carcinomatosis of colorectal or ovarian origin.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Effectiveness of Venclexta (Venetoclax) in Patients With Relapse or Refractory Chronic Lymphocytic Leukemia in Routine Clinical Practice in Russian Federation
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Cancer
Interventions: DRUG: Venetoclax
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Spirometry Expert Support in General Practice
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma|Cough|Dyspnea
Interventions: PROCEDURE: expert support for interpretation of spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Three New Ideas to Protect Special Forces From the Stress of High Altitude
Status: COMPLETED
Conditions: Mountain Sickness
Interventions: DIETARY_SUPPLEMENT: Quercetin|DRUG: Nifedipine extended release|DRUG: Methazolamide|DRUG: Metformin|DRUG: Placebo|DRUG: Nitrite
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Inhaled PUL-042 on Rhinovirus-induced Symptoms in Smokers With GOLD Stage 0 COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Sterile Water Injection|DRUG: PUL-042 Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Autonomic Modulation in Thoracic Surgery
Status: TERMINATED
Conditions: Atrial Fibrillation, Postoperative|Postoperative Complications|Inflammation
Interventions: DEVICE: Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)|DEVICE: Sham LLVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Elderly Patients With Renal Insufficiency: Reasons for Using the Geriatrician, Modalities and Results of the Geriatric Evaluation, Becoming at One Year
Status: COMPLETED
Conditions: Secondary Evaluation Criteria|Comorbidities and Coexisting Conditions|Motility Disorder
Interventions: OTHER: geriatric nephrology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Antidepressant Therapy on Brain Dopamine Transporter Activity in People With Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: S-citalopram|BEHAVIORAL: Cognitive behavioral therapy (CBT)|PROCEDURE: TRODAT-1 single photon emission computed tomographic (SPECT) imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption in Young Subjects (≤ 45 Years) Hospitalized for an Ischaemic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Cannabis Use
Interventions: OTHER: Drug urinal test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali
Status: TERMINATED
Conditions: Tuberculosis, Pulmonary|Mycobacterium Tuberculous|Antitubercular Agents|Tuberculosis, Mulutidrug-Resistant|Extensively Drug-Resistant|Extensibely Drug-Resistant Tuberculosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Colchicine for the Stability of Coronary Plaque in Acute Coronary Syndrome (COLOCT)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High Intensity Stepping Training on Gait in Patients With Ataxia
Status: NOT_YET_RECRUITING
Conditions: Cerebellar Ataxia
Interventions: DEVICE: Polar H10 heart rate monitor|DEVICE: Therastride Treadmill System|DEVICE: VECTOR Bioness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacodynamics (PD) of Prednisoline in Healthy Male Subject
Status: COMPLETED
Conditions: Immunoscience
Interventions: DRUG: Prenisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Primary Chemotherapy With Paclitaxel, Gemcitabine, and Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel/Gemcitabine/Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT