pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar Depression
Status: UNKNOWN
Conditions: Bipolar Depression
Interventions: DEVICE: Deep TMS Treatment|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Connective Tissue Graft Technique|PROCEDURE: Pinhole Surgical Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Body Suspension and Tilting Exercises in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Intervention group (Body body suspension and tilting exercises)|OTHER: Control group (global muscle stretching)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infant Restore: Efficacy of Microbiome Analysis and Education
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbiota|Eczema|Microbiome|Gut Microbiome
Interventions: DIETARY_SUPPLEMENT: Tailored Recommendations|BEHAVIORAL: Consult Call|BEHAVIORAL: Email Series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Demonstrate the Efficacy and Safety of Secukinumab up to 224 Weeks in Subjects With Active Peripheral Spondyloarthritis (pSpA).
Status: WITHDRAWN
Conditions: Active Peripheral Spondyloarthritis (pSpA)
Interventions: BIOLOGICAL: Secukinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG).
Status: RECRUITING
Conditions: Obesity|Postoperative Pain|Postoperative Nausea and Vomiting|Opioid Use
Interventions: DRUG: Pregabalin 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Providing Coffee to Patients Postoperatively to Decrease Length of Stay in the PACU
Status: ACTIVE_NOT_RECRUITING
Conditions: PACU Length of Stay|Postoperative Nausea|Postoperative Vomiting|Patient Satisfaction
Interventions: DIETARY_SUPPLEMENT: Coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia A
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: ITI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain
Status: UNKNOWN
Conditions: Pelvic Floor Myofascial Pain|Pelvic Pain|Myofascial Pain
Interventions: DEVICE: vaginal cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HybridAPC for Gastric Mucosal Ablation in Obese Patients.
Status: RECRUITING
Conditions: Obesity|Adiposity
Interventions: DEVICE: Hybrid Argonplasma coagulation (HAPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids
Status: COMPLETED
Conditions: Hyperalgesia
Interventions: DRUG: Propranolol|DRUG: Placebo to Match Propranolol|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD2811 and Durvalumab (MEDI4736) Combination Therapy in Relapsed Small Cell Lung Cancer
Status: TERMINATED
Conditions: SCLC, Recurrent
Interventions: DRUG: Durvalumab+AZD2811 to SCLC patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 90Y-hMN14 to Treat Colorectal Cancer Patients With Limited Residual Disease After Surgery
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: hMN14 (labetuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Clinical Inertia in Hypertension Treatment: A Pragmatic Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Active Outreach to Patients and Providers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intra- and Inter-individual Differences of Pain
Status: COMPLETED
Conditions: Experimental Pain in Healthy Human Subjects
Interventions: DEVICE: painful stimulation by using a laser device (DEKA Stimul 1340, Calenzano, Italy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Ulcer Healing in Patients Taking Rabeprazole With Different Antiplatelets
Status: UNKNOWN
Conditions: Gastric Ulcer|Duodenal Ulcer
Interventions: DRUG: rabeprazole plus aspirin versus rabeprazole plus clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer
Status: UNKNOWN
Conditions: Healthy Subjects, Drug-drug Interaction, Pyrotinib
Interventions: DRUG: Pyrotinib Maleate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers
Status: UNKNOWN
Conditions: Vaginosis, Bacterial
Interventions: DRUG: Etonogestrel /Ethinyl Estradiol Contraceptive Vaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Poster on Dysphagia-specific Food Procedures: Usability and Impact
Status: UNKNOWN
Conditions: Dysphagia
Interventions: DEVICE: Placement of a poster in patients' rooms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pegylated Human Recombinant Arginase for Liver Cancer (BCT-100-002)
Status: COMPLETED
Conditions: Neoplasm|Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Pegylated Recombinant Human Arginase I
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer
Status: RECRUITING
Conditions: Platinum-resistant Ovarian Cancer|Refractory Ovarian Carcinoma
Interventions: DRUG: CBX-12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Examine The Distribution Of PF-05212377 In The Brain Of Healthy Volunteer Subjects Using Positron Emission Tomography And A Radioactive Tracer Following Oral Administration Of One Dose Of PF-05212377
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05212377|DRUG: PF-05212377|DRUG: PF-05212377
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of a Psychosomatic Intervention
Status: COMPLETED
Conditions: Type D Personality|Trauma, Psychological
Interventions: PROCEDURE: Psychosensory Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UI-EWD for Endoscopic Hemostasis of Bleeding Peptic Ulcers and Bleeding After EMR/ESD
Status: COMPLETED
Conditions: Upper Gastrointestinal Bleeding
Interventions: DEVICE: UI-EWD Hemostatic system|DRUG: epinephrine endoscopic injection (conventional therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non Motoric Reactions in Vojta Reflex Locomotion
Status: ACTIVE_NOT_RECRUITING
Conditions: Locomotion Disorder, Neurologic
Interventions: OTHER: Reflex locomotion according to Vojta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Implementation Study of Interventions to Promote Safe Motherhood in Jimma Zone Ethiopia
Status: COMPLETED
Conditions: Maternal Mortality|Maternal Morbidity
Interventions: OTHER: MWA intervention|OTHER: IEC intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Methods to Remove Residual Orthodontic Adhevsie
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: PROCEDURE: Recycling orthodontic brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Study to Assess the Absorption, Distribution, Metabolism and Excretion of AZD1656 in Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DEVICE: AZD1656
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-reported Outcome Measures Comparing Static Computer-aided Implant Surgery and Conventional Implant Surgery
Status: COMPLETED
Conditions: Dental Implantation|Postoperative Pain|Computer-assisted Surgery|Patient Outcome Assessment|Dental Anxiety|Quality of Life|Oral Health
Interventions: OTHER: Modified Dental Anxiety Score (MDAS) questionnaire|OTHER: Pain questionnaire|OTHER: Oral Health-Related Quality of Life (OHRQoL) questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ocular Responses to Short and Long-term Lens Wear
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: Purevision Lenses with ReNu Multiplus|DEVICE: Purevision Lenses with Optifree RepleniSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV|Melanoma
Interventions: BIOLOGICAL: ADP-TILIL7|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|DRUG: Proleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3a Follicular Lymphoma|Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type|Refractory Grade 1 Follicular Lymphoma|Refractory Grade 2 Follicular Lymphoma|Refractory Grade 3a Follicular Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Stage IB Mycosis Fungoides AJCC v7|Stage II Mycosis Fungoides AJCC v7|Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage III Mycosis Fungoides AJCC v7|Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma|Stage IV Mycosis Fungoides AJCC v7
Interventions: BIOLOGICAL: Anti-ICOS Monoclonal Antibody MEDI-570|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Medial Raw Anchor Necessary During Tendon Repair Combined With Microfracture
Status: ENROLLING_BY_INVITATION
Conditions: Full Rotator Cuff Tear|Microfracture Procedure|Double Raw Repair|Lateral Raw Repair
Interventions: PROCEDURE: lateral raw|PROCEDURE: double raw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Craniosacral Therapy as a Self-help Strategy for Patients With Chronic Non-specific Back Pain
Status: RECRUITING
Conditions: Low Back Pain, Mechanical|Complementary Therapies|Progressive Muscle Relaxation
Interventions: PROCEDURE: Craniosacral Therapy (CST) self-help techniques|PROCEDURE: Progressive Muscle Relaxation (PMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Apps to Reduce Distress in Breast Cancer Survivors Using an Adaptive Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Anxiety|Engagement, Patient
Interventions: BEHAVIORAL: IntelliCare|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Risk-stratified Sequential Treatment of Post-transplant Lymphoproliferative Disease (PTLD) With Rituximab SC and Immunochemotherapy
Status: COMPLETED
Conditions: Posttransplant Lymphoproliferative Disorder
Interventions: DRUG: Rituximab sc|DRUG: Rituximab sc consolidation|DRUG: Rituximab sc combined with CHOP chemotherapy|DRUG: Rituximab sc combined with alternating chemotherapy with CHOP and DHAOx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Neuromuscular, Circulatory and Biomechanical Responses After Cryotherapy
Status: UNKNOWN
Conditions: Healthy Individuals
Interventions: OTHER: cryotherapy by immersion|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CHEckpoint Inhibition in Combination With an Immunoboost of External Beam Radiotherapy in Solid Tumors
Status: COMPLETED
Conditions: Urothelial Carcinoma|Melanoma|Renal Cell Carcinoma|Non-small Cell Lung Cancer|Head and Neck Cancer
Interventions: DRUG: Nivolumab or Pembrolizumab or Atezolizumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using T-Cell Alloreactivity and Chimerism to Guide Immunosuppression Minimization in Intestinal Transplantation
Status: RECRUITING
Conditions: Intestinal Transplantation
Interventions: BIOLOGICAL: Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Beclomethasone in Healthy Athletes
Status: UNKNOWN
Conditions: Performance, Detection|Doping
Interventions: DRUG: Beclomethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Testing the Feasibility of Intervening to Optimize Chiropractic Care for Adults With Neck Pain Disorders
Status: COMPLETED
Conditions: Neck Pain
Interventions: BEHAVIORAL: Multifaceted KT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nivolumab, S-1 Combined With Oxaliplatin Versus Nivolumab as Neoadjuvant Therapy in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Chemotherapy Effect
Interventions: DRUG: Nivolumab plus SOX|DRUG: Nivolumab|PROCEDURE: Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microvascular and Cardiac Dysfunction in Paroxysmal Nocturnal Hemoglobinuria and Sickle Cell Disease
Status: COMPLETED
Conditions: Rheologic Disease|Sickle Cell Disease|Paroxysmal Nocturnal Hemoglobinuria
Interventions: OTHER: Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-term Study to Determine Safety and Efficacy of Dutasteride in Male Subjects With Androgenetic Alopecia
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: Dutasteride 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Uveitis Steroid Treatment (MUST) Trial
Status: COMPLETED
Conditions: Uveitis
Interventions: DRUG: fluocinolone acetonide intraocular implant|DRUG: oral corticosteroid with immunosuppressive agents as needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fiber Intervention on Gut Microbiota in Children With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome|Hyperphagia
Interventions: OTHER: Fiber intervention|OTHER: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot Randomized Control Trial
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: Moderate Intensity Aerobic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of GX-E2 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GX-E2|DRUG: GX-E2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Combination Tumor Treating Fields (TTF; Optune), Nivolumab Plus/Minus Ipilimumab for Recurrent Glioblastoma
Status: TERMINATED
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Nivolumab 240 mg IV|DRUG: Nivolumab 3 mg/kg|DRUG: Ipilimumab 1 mg/kg|DEVICE: NovoTTF200A (Optune)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma, Malignant|Computer-Assisted
Interventions: DIAGNOSTIC_TEST: Validation of IDH1 mutations from the radiomics model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Multimodal Neuroimaging Parameters in Women With Postpartum Depression Who Are Receiving ZULRESSO™ (Brexanolone)
Status: WITHDRAWN
Conditions: Postpartum Depression
Interventions: DRUG: Brexanolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Efficacy of a Two Daily Mixed Insulin Injection Versus a Basal-bolus Scheme With Human Insulin
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: premix insulin human isophane suspension and insulin human|DRUG: Humulin N plus Humulin R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Exploratory Study of Electroacupuncture in the Treatment of Peripheral Neuropathy Induced by Platinum Based Chemotherapy Drugs
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Safety and Pharmacokinetics of 2 Different Single Doses of NNC128-0000-2011 in Haemophilia A or B Patients
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: NNC 0128-0000-2011|DRUG: NNC 0128-0000-2011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Cobas® 4800 HPV Test for the Detection of High-grade Cervical Disease
Status: COMPLETED
Conditions: Human Papilloma Virus (HPV)
Interventions: DEVICE: cobas® 4800 HPV Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Compare the Oncological Benefit of Deep Neuromuscular Block in Gastric Cancer Obesity Patient
Status: COMPLETED
Conditions: Gastric Cancer|Obesity
Interventions: DRUG: Sugammadex Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Vitamin-B-complex on Cognitive Ability of Kindergarten Kids
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamine-B and Folic Acid Complex, calcium|DIETARY_SUPPLEMENT: calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nanocytology Test to Evaluate Skin Cancer in High Risk Patients
Status: COMPLETED
Conditions: Actinic Keratosis|Squamous Cell Carcinoma
Interventions: PROCEDURE: Superficial shave biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Conjugated Linoleic Acid (CLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP3662
Status: COMPLETED
Conditions: Pharmacokinetics of ASP3662|Displacement of Radiotracer|Healthy Volunteers
Interventions: OTHER: [11C]AS2471907|RADIATION: Positron Emission Tomography (PET)|DRUG: ASP3662
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Strattice in Repair of Inguinal Hernias
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: Inguinal hernia repair with Ultrapro|DEVICE: Inguinal hernia repair with Strattice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Intervention to Improve Physical Activity Behaviour In Overweight and Obese Adolescents
Status: COMPLETED
Conditions: Adolescent Behavior|Adolescent Obesity|Adolescent Overweight
Interventions: BEHAVIORAL: FIT-TEENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LUCY Study: TriVascular Evaluation of Females Who Are Underrepresented Candidates for Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Ovation Abdominal Stent Graft Platform
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Investigate the Effect of an Investigational Drug on Electrocardiogram Intervals in Adults With Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP363856 150 mg|DRUG: Placebo|DRUG: moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual 360°-Tour in Coronary Computed Tomography
Status: COMPLETED
Conditions: Coronary Artery Disease|Anxiety|Fear
Interventions: OTHER: Virtual tour in coronary computed tomography - 360° counselling environment|OTHER: Current practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Relative Bioavailability Study in Healthy Male Subjects for ZD4054 (Zibotentan) Immediate Release Tablets.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ZD4054|DRUG: ZD4054|DRUG: ZD4054|DRUG: ZD4054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clostridium Difficile Vaccine Efficacy Trial
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Clostridium difficile vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Investigate the Effect of Macitentan on the Concentrations of Rosuvastatin in the Blood of Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Rosuvastatin|DRUG: Macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Investigate Efficacy and Safety of Pemetrexed as Second or Third Line Therapy in Patients With Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pemetrexed 500 mg/m2|DRUG: Pemetrexed 1000 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ranibizumab 0.5MG, or 1.0mg for RVO With Macular Edema Previously Receiving Bevacizumab
Status: COMPLETED
Conditions: Branch Retinal Vein Occlusion|Central Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: ranibizumab 0.5mg|DRUG: ranibizumab 1.0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking
Status: RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Nicotine Use Disorder
Interventions: BEHAVIORAL: Contingency Management|BEHAVIORAL: Non-contingent control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: TAK-700|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Stulln and Accommodative Training
Status: WITHDRAWN
Conditions: Accommodation Disorder|Visual Fatigue
Interventions: DRUG: Stulln Eyedrops|DRUG: Thera Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma
Status: COMPLETED
Conditions: Metastatic Osteosarcoma|Recurrent Osteosarcoma|Refractory Osteosarcoma|Stage IV Osteosarcoma AJCC v7|Stage IVA Osteosarcoma AJCC v7|Stage IVB Osteosarcoma AJCC v7
Interventions: BIOLOGICAL: Denosumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
Status: COMPLETED
Conditions: Adult Acute Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Asparaginase|DRUG: Methotrexate|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: G-CSF|DRUG: Vindesine|DRUG: Etoposide|DRUG: Prednisolone|DRUG: Adriamycin|DRUG: Thioguanine|DRUG: Teniposide|PROCEDURE: CNS irradiation|PROCEDURE: Mediastinal Irradiation|PROCEDURE: Stem cell transplantation (SCT)|DRUG: Idarubicin|DRUG: Fludarabine|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study Comparing PF-06439535 And Bevacizumab In Healthy Male Volunteers (REFLECTIONS B739-01)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-06439535|BIOLOGICAL: Avastin|BIOLOGICAL: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation of Perioperative Brain Metabolites With Postoperative Delirium in Elderly Oral Craniomaxillofacial Surgery Patients
Status: RECRUITING
Conditions: Delirium in Old Age
Interventions: OTHER: Collecting clinical data, blood gas data, Magnetic Resonance Spectroscopy (MRS) data and blood,urine, and feces sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Magnetic Stimulation (TMS) for Thoracic Surgery
Status: WITHDRAWN
Conditions: Thoracic Surgery|Chronic Pain|Transcranial Magnetic Stimulation|Neuromodulation
Interventions: DEVICE: active TMS|DEVICE: sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Renal Denervation for the Treatment of Resistant Hypertension
Status: UNKNOWN
Conditions: Uncontrolled Hypertension
Interventions: DEVICE: Ultrasound-based Renal Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AL-2 MP-1 (Polyimide) Acetabular Liner
Status: UNKNOWN
Conditions: Osteoarthritis|Avascular Necrosis|Rheumatoid Arthritis|Congenital Dysplasia of the Hip|Ankylosing Spondylitis|Post-traumatic; Arthrosis|Injury of Hip
Interventions: DEVICE: MP-1 Polymer on Ceramic Articulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Ointment Pharmacokinetics in Infants With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Tacrolimus Ointment 0.03%|DRUG: Tacrolimus Ointment 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Collagen Membrane Combined With HUC-MSCs Transplantation in Patients With Nasal Septum Perforation
Status: UNKNOWN
Conditions: Chronic Nasal Septum Perforation
Interventions: BIOLOGICAL: Collagen membrane + HUC-MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Neurocognitive Model of Distancing Using Transcranial Magnetic Stimulation.
Status: COMPLETED
Conditions: Emotion Regulation|Real Versus Sham Transcranial Magnetic Stimulation (TMS)
Interventions: DEVICE: Transcranial magnetic stimulation task|DEVICE: Sham transcranial magnetic stimulation task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of Virtual Simulation-Based Diabetes Foot Care Education in Patients With Diabetes in Ethiopia
Status: RECRUITING
Conditions: Diabetes Foot Care
Interventions: BEHAVIORAL: Diabetes Foot Care Education (DFCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3375880 in Adults With Moderate-to-Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: LY3375880|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CB307 in Patients With Advanced and/or Metastatic PSMA-positive Tumours.
Status: RECRUITING
Conditions: Advanced and/or Metastatic Solid Tumours
Interventions: DRUG: CB307
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating Efficacy of Duct Tape for Treatment of Warts
Status: COMPLETED
Conditions: Wart|Common Wart|Verruca Vulgaris|Verruca Plantaris|Plantar Wart
Interventions: DEVICE: duct tape occlusion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
Status: COMPLETED
Conditions: Cervical Cancer|Vulvar Cancer|Vaginal Cancer|CIN1|CIN2|CIN3|VaIN1|VaIN2|VaIN3|Genital Wart|VIN 1|VIN 2|VIN 3|AIS
Interventions: BIOLOGICAL: 4-valent HPV Vaccine|BIOLOGICAL: 9-valent HPV Vaccine|BIOLOGICAL: GARDASIL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Management of Popeye Sign With Botulinum Toxin After Bicepstenotomy
Status: UNKNOWN
Conditions: Popeye Syndrome
Interventions: DRUG: Botulinum toxin type A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of RR110 in Patients With Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: RR110 (Tamibarotene)|DRUG: RR110 (Tamibarotene)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease
Status: COMPLETED
Conditions: Patients Aged 65-85 (Both Included)|Diagnosed of Mild Cognitive Impairment|Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years
Interventions: DEVICE: Smart pillbox|OTHER: Interactive digital platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clove In The Treatment Of Relapsed Or Resistant Acute Leukemia In Children
Status: COMPLETED
Conditions: Acute Leukemia
Interventions: DRUG: Clofarabine VP 16 ciclophospahamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hesperidin on Glucose / Insulin Metabolism
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Hesperidin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: glucarpidase (50 Units/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application Strategies of Maxillary Sinus Buccal Bony Window
Status: RECRUITING
Conditions: Sinus Floor Augmentation|Maxillary Sinus
Interventions: PROCEDURE: different methods for maxillary sinus floor elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iTTo for Treatment Naive Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Status: COMPLETED
Conditions: Gastroesophageal Junction Adenocarcinoma|Advanced Gastric Carcinoma
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: TAS 102 (Trifluridine/Tipiracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction
Status: TERMINATED
Conditions: Tooth Extraction
Interventions: DRUG: Tranexamic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Kidney Diseases|Diabetic Nephropathies|Diabetes Complications|Diabetes Mellitus|Endocrine System Diseases
Interventions: DRUG: GFB-024|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Disitamab Vedotin Combined With Gemcitabine in Neoadjuvant Treatment of Urothelial Carcinoma
Status: RECRUITING
Conditions: Radical Cystectomy|Urothelial Carcinoma
Interventions: DRUG: Disitamab Vedotin and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Using Doxorubicin and Paclitaxel in Treating Women With Large Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Doxorubicin followed by Paclitaxel|OTHER: Paclitaxel followed by Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Intramuscular Olanzapine Depot to Oral Olanzapine and Low-Dose Depot in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenic Disorders
Interventions: DRUG: Intramuscular Olanzapine Depot|DRUG: Oral Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Validating the Effect og Ondansetron and Mirtazapine in Treating Hyperemesis Gravidarum
Status: TERMINATED
Conditions: Hyperemesis Gravidarum|Nausea Gravidarum|Vomiting of Pregnancy
Interventions: DRUG: Mirtazapine|DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-55375515 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-55375515|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Emtricitabine in Combination With Other Antiretroviral Agents in HIV Infected Pediatric Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of the Neoadjuvant Chemotherapy for IB2 and IIA2 Stage Cervical Cancer Patients
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasm|Cervical Cancer|Uterine Cervical Cancer
Interventions: DRUG: NACT|PROCEDURE: RT+PLND|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is ESWT Better in Plantar Fasciitis Treatment?
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: DEVICE: extracorporeal Shock wave therapy|DRUG: Corticosteroid injection|DEVICE: Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria，IgA Nephropathy
Interventions: DRUG: HRS-5965 tablets；HRS-5965 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGNET (Magnetically Controlled Capsule for Assessment of Gastric Mucosa in Symptomatic Patients)
Status: COMPLETED
Conditions: Abdominal Pain|Gastritis|Gastric Ulcer|Gastric Cancer
Interventions: DEVICE: MAGNET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Dose-ranging Pediatric Study of an Adjuvanted Pandemic Influenza Vaccine
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: H5N1 antigen combined with MF59 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neurotoxicity
Interventions: DRUG: Ginkgo Biloba|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia|Chronic Myeloid Leukemia, BCR-ABL1 Positive|Hematopoietic and Lymphoid System Neoplasm|Hodgkin Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Biospecimen Collection|DRUG: Granulocyte Colony-Stimulating Factor|DRUG: Hematopoietic Cell Transplantation Conditioning Regimen|BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine|PROCEDURE: Pheresis|DRUG: Placebo Administration|DRUG: Stem Cell Mobilization Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Lung Protective Ventilation With ECCO2R During ARDS
Status: TERMINATED
Conditions: ARDS, Human|Ventilator-Induced Lung Injury
Interventions: DEVICE: Low flow Extracorporeal CO2 removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Cutaneous Scar Quality Following Bilateral Breast Reduction With the PEAK PlasmaBlade 4.0
Status: TERMINATED
Conditions: Macromastia
Interventions: DEVICE: PEAK PlasmaBlade 4.0|DEVICE: Traditional Electrosurgery with scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alfacalcidol on Muscle Strength in Elderly Indonesian Women : A Randomized Controlled Trial
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DRUG: alfacalcidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Ischemic Heart Disease
Interventions: DRUG: vildagliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 611 in Chinese Adults With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: 611 Q2W|DRUG: 611 Q4W|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: adalimumab|DRUG: adalimumab|DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT