pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: gemtuzumab ozogamicin|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Electronic Monitoring Device on Maintaining a Correct Elevation of Head of Bed for Mechanically-ventilated Patients in Intensive Care Unit
Status: TERMINATED
Conditions: Mechanically-ventilated Patients
Interventions: DEVICE: EMD (Inclinomax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Macular Pigment Carotenoids in the Pathogenesis and Treatment of Macular Telangiectasia Type 2 (MacTel)
Status: COMPLETED
Conditions: Idiopathic Juxtafoveal Telangiectasia
Interventions: DRUG: zeaxanthin|DRUG: zeaxanthin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate THR-317 Treatment for Macular Telangiectasia Type 1 (MacTel 1)
Status: COMPLETED
Conditions: Retinal Telangiectasis|Idiopathic Juxtafoveal Retinal Telangiectasia
Interventions: DRUG: THR-317 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: lenvatinib|BIOLOGICAL: pembrolizumab|DRUG: saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers
Status: COMPLETED
Conditions: Gastroduodenal Ulcer
Interventions: DRUG: Naproxen|DRUG: Aspirin|DRUG: Celecoxib|DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Molecular Breast Imaging and Digital Breast Tomosynthesis in Screening Patients With Dense Breast Tissue
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma
Interventions: PROCEDURE: Digital Tomosynthesis Mammography|RADIATION: Scintimammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Phytochemicals From Theobroma Cacao on Mental Energy
Status: COMPLETED
Conditions: Mental Fatigue
Interventions: OTHER: Caffeinated cocoa|OTHER: Cocoa|OTHER: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: B. Lactis HN019 for Functional Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: B. lactis HN019|DIETARY_SUPPLEMENT: B. lactis HN019|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Phonophoresis With Vitamin B12 on CTS
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Vitamin B12 phonophoresis|DEVICE: Placebo Vitamin B12 phonophoresis|DEVICE: Wrist splint|OTHER: tendon and nerve gliding exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Injection-Molding Vs. Incremental Packing of Resin Composite in Cavitated Posterior Teeth
Status: RECRUITING
Conditions: Caries Class II
Interventions: PROCEDURE: Injection molding|PROCEDURE: Incremental packing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptomatic Response to Gluten Challenge in Patients With Suspected Non Celiac Gluten Sensitivity
Status: COMPLETED
Conditions: Non Celiac Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: gluten|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Characterisation of the Gut Microbiota in Term Infants After Maternal Supplementation of Probiotics
Status: COMPLETED
Conditions: Infant Development|Gut Microbiome
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study of Thermodox as Adjuvant Therapy With Thermal Ablation (RFA) in Treatment of Metastatic Colorectal Cancer(mCRC)
Status: TERMINATED
Conditions: Colon Cancer Liver Metastasis
Interventions: DRUG: Lyso-Thermosensitive Liposomal Doxorubicin|OTHER: 5% Dextrose Solution|DRUG: ThermoDox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Nerve Stimulation (VeNS) as a Method of Sleep Management in People With PTSD
Status: WITHDRAWN
Conditions: PTSD|Sleep Disturbance|Insomnia
Interventions: DEVICE: Modius Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: Fecal microbiota transplantation (FMT) Single FMT infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: ALN-CC5|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplementation Effects on Rehabilitation Outcomes in Rotator Cuff Pathology
Status: TERMINATED
Conditions: Rotator Cuff/Shoulder Structure and Function
Interventions: DIETARY_SUPPLEMENT: Placebo (maltodextrin)|DIETARY_SUPPLEMENT: Multi-nutrient Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Insulin Treatment on Postprandial Platelet Activation in Patients With Non-insulin-dependent Diabetes Mellitus (NIDDM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Postprandial Hyperglycemia
Interventions: DRUG: Insulin aspart (Novorapid®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture Ribs
Status: UNKNOWN
Conditions: Fracture; Rib, Multiple
Interventions: DRUG: Pregabalin 150mg|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Basmisanil in Adults With Severe Motor Impairment Following an Ischemic Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Basmisanil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Uremic Pruritus by Olive-omega 3 Ointment
Status: UNKNOWN
Conditions: Uremic Pruritus
Interventions: PROCEDURE: application of ointment (olive-omega 3 ointment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of rhBMP-2/ACS/Allograft Bone Dowel for Anterior Lumbar Interbody Fusion in Patients With Symptomatic Degenerative Disc Disease
Status: TERMINATED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/ACS/allograft bone dowel|PROCEDURE: Autogenous bone/allograft bone dowel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete Remission
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venclexta 100 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palmitoylethanolamide and Polydatin in Pediatric Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: palmithoylethanolamide/polydatin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients
Status: COMPLETED
Conditions: High Caries Risk Patients|Caries|Antimicrobial Effect|Side Effect
Interventions: DRUG: Arabic, Gum|DRUG: Licorice Root|DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inhaled Ondansetron & Dyspnea
Status: COMPLETED
Conditions: Dyspnea
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Cross-over, Open-labelled Test Catheter Acceptance Study
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: test intermittent catheter|DEVICE: Intermittent catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine Suan Tsao Jen Tang and Tian-Wang-Bu-Xin Dan in Patients With Primary Insomnia.
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: TIAN WANG BU XIN DAN|DRUG: Suan Tzao Ren Tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine on Bone Mass in Postmenopausal Women
Status: UNKNOWN
Conditions: Postmenopausal Women
Interventions: DIETARY_SUPPLEMENT: Creatine supplementation|DIETARY_SUPPLEMENT: dextrose (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperkalaemia|Chronic Kidney Disease
Interventions: DRUG: Sodium Zirconium Cyclosilicate (SZC)|DRUG: Local standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Arimidex and Radiotherapy Sequencing
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Pre-radiotherapy commencement of Arimidex|DRUG: Post radiotherapy commencement of Arimidex|RADIATION: Radiotherapy|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Therapeutics Smartphone Application for Methamphetamine Use Disorder
Status: COMPLETED
Conditions: Methamphetamine Abuse
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Counseling|BEHAVIORAL: Approach Bias Modification|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Status: RECRUITING
Conditions: Brain Concussion|Mild Traumatic Brain Injury|Headache|Post-Concussion Symptoms
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Ovarian Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Carcinoma
Interventions: PROCEDURE: Radiofrequency ablation|BIOLOGICAL: Cytokine-induced killer cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Reactivated DEFINITY or LUMASON in Patients Undergoing Rest or Stress Echocardiography
Status: RECRUITING
Conditions: Stress Echocardiography
Interventions: OTHER: perflutren lipid microsphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: Galcanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: a Randomized Controlled Trial of the Intake of Organic and Inorganic Phosphate in Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: OTHER: Diet containing organic phosphate|OTHER: Diet containing inorganic phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Homoeopathic Association in Aortic Valve Surgery
Status: COMPLETED
Conditions: Aortic Valve Replacement
Interventions: DRUG: placebo|DRUG: Arnica and Bryonia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy to the Cervical Spine and Diaphragm Combined With Breathing Reeducation Exercises, in nsCNP Patients
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: OTHER: Cervical plus Diaphragmatic Manual Therapy plus Breathing Reeducation Exercises|OTHER: Cervical Manual Therapy plus sham Diaphragmatic Manual Therapy|OTHER: Conventional Physiotherapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Changes in Muscle Secretome in the Remission of Type 2 Diabetes Mellitus Induced by Bariatric Surgery
Status: UNKNOWN
Conditions: Diabete Type 2
Interventions: DIAGNOSTIC_TEST: Muscle biopsy and blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Study of Safety and Efficacy of PET-adapted Treatment With Nivolumab, Bendamustine, Gemcitabine, Vinorelbine (Nivo-BeGEV) in Patients With Relapsed/Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: B-cell Adult Acute Lymphoblastic Leukemia|B-cell Childhood Acute Lymphoblastic Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Lymphoblastic Lymphoma|T-cell Adult Acute Lymphoblastic Leukemia|T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: L-asparaginase|DRUG: doxorubicin hydrochloride|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|DRUG: cytarabine|DRUG: prednisone|DRUG: bortezomib|DRUG: pegaspargase|DRUG: methotrexate|DRUG: etoposide phosphate|DRUG: cyclophosphamide|BIOLOGICAL: filgrastim|DRUG: leucovorin calcium|OTHER: laboratory biomarker analysis|DRUG: High Dose MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes After Transoral Incisionless Fundoplication (TIF) Following Successful Endoscopic Ablation for Barrett's Esophagus
Status: ENROLLING_BY_INVITATION
Conditions: Barrett Esophagus|Transoral Incisionless Fundoplication
Interventions: DEVICE: TIF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repurposing Low-Dose Clonidine for PTSD in Veterans
Status: RECRUITING
Conditions: PTSD|Posttraumatic Stress Disorder|Sleep
Interventions: DRUG: Clonidine Pill|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pore Excision, Curettage, and Injection of Cymetra for Pilonidal Disease
Status: UNKNOWN
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: surgery (Pore Excision, Curettage, and Injection of Cymetra)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-dependent Lung High Frequency Positive Pressure Ventilation (HFPPV) and Right Ventricular Function
Status: COMPLETED
Conditions: Lung Diseases|Esophageal Diseases
Interventions: PROCEDURE: conventional OLV followed with IL-HFPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of ALIMTA (Pemetrexed) Plus Gemcitabine in Locally Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Urologic Neoplasms
Interventions: DRUG: ALIMTA|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: VisuMax SMILE procedure for the reduction or elimination of myopia with astigmatism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Dasotraline in Children 6 to 12 Years of Age With Attention-Deficit Hyperactivity Disorder (ADHD) in a Simulated Classroom Setting.
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: dasotraline 4mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Sarcoma
Interventions: GENETIC: clonality analysis|GENETIC: microsatellite instability analysis|GENETIC: mutation analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sulforaphane-rich Broccoli Sprout Extract for Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Sulforaphane-rich Broccoli Sprout Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Daridorexant in Chinese Patients With Insomnia Disorder
Status: RECRUITING
Conditions: Insomnia Disorder
Interventions: DRUG: Daridorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nitrous Oxide on EEG
Status: COMPLETED
Conditions: Nitrous Oxide|Electroencephalography|Anesthetic, Inhalation
Interventions: DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SPARC Smartphone Application for the Management of Sarcoidosis-Associated Fatigue
Status: COMPLETED
Conditions: Sarcoidosis|Fatigue
Interventions: BEHAVIORAL: Sarcoidosis Patient Assessment and Resource Companion App|BEHAVIORAL: Enhanced Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Robotics-assisted Tilt Table and Functional Electrical Stimulation in Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Robot assisted inclined bed treatment and FES|DEVICE: conventional inclined bed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen Oral Suspension
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: A1: Ibuprofen/Acetaminophen Fixed dose combination oral suspension (Laboratorios Silanes S.A. de C.V.)|DRUG: A2: Ibuprofen (Advil®, Pfizer S.A. de C.V.)|DRUG: A3: Acetaminophen (Tylenol®, from Janssen-Cilag, S.A. de C.V.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Weigh the Effect of Exercise Training on BONE (SWEET-BONE) Quality and Strength in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: supervised exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypotensive Anesthesia for Orthognathic Surgery
Status: NOT_YET_RECRUITING
Conditions: Hypotensive Anesthesia|Orthognathic Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Nicardipine|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ROSA Knee System vs Conventional Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Robotic-assisted total knee arthroplasty (raTKA)|PROCEDURE: conventional total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Changes in Transpulmonary Pressure During Recruitment Maneuver in Patients Under Pressure Supported Mechanical Ventilation
Status: WITHDRAWN
Conditions: ARDS, Human
Interventions: PROCEDURE: alveolar recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-label Study to Evaluate the Long-term Safety of MEDI-546, for the Treatment of SLE, in Adults
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: BIOLOGICAL: Anifrolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Wake and Light Therapy for Depression
Status: COMPLETED
Conditions: Depression|Depressive Disorder, Major|Depression, Unipolar|Depression Moderate
Interventions: BEHAVIORAL: Wake and Light Therapy|BEHAVIORAL: Sleep and Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation and Impact of Paediatric Malnutrition Screening Tool in Hospitalised Children
Status: COMPLETED
Conditions: Malnutrition
Interventions: OTHER: questionnaire STAMP and dietary|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomised Controlled Trial of Face Masks and Hand Hygiene in Reducing Influenza Transmission in Households
Status: COMPLETED
Conditions: Influenza
Interventions: BEHAVIORAL: hand hygiene|OTHER: health education|DEVICE: face masks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Status: COMPLETED
Conditions: Opioid-use Disorder|Addiction|Depression|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Collaborative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Duloxetine (LY248686) in Japanese Children and Adolescents With Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Duloxetine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Single Ascending Doses Of PBL 1427 In Healthy Volunteers
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Matching placebo|DRUG: PBL 1427 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Two-Arm Proof of Concept Study Testing A Novel Approach to Exercise Promotion Based on Affect-regulation
Status: RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Core Exercise Promotion Program|BEHAVIORAL: Affect-based exercise prescription|BEHAVIORAL: Effort-based exercise prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lumbar Stabilization Exercises in Adult Patients With Lumbar Arthrodesis Surgery
Status: COMPLETED
Conditions: Arthrosis; Spine|Spinal Stenosis Lumbar
Interventions: OTHER: Experimental: Local Stabilization Exercise|OTHER: Experimental: Global Stabilization Exercise|OTHER: Experimental: Mixed Stabilization Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.
Status: RECRUITING
Conditions: Late Effects|Testicular Germ Cell Tumor Mixed|Non-Metastatic Breast Carcinoma|Soft Tissue Sarcoma, Adult, Stage IIC|Osteosarcoma|Ewing's Sarcoma|Acute Myeloid Leukemia|Hodgkin Disease|Non Hodgkin Lymphoma
Interventions: OTHER: PASCA intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Telerehabilitation-Based Exercise and Training on Outcome Measures in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Knee Arthritis
Interventions: OTHER: Telerehabilitation|OTHER: Paper Based Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery
Status: UNKNOWN
Conditions: Craniotomy Tumor Removal Surgery
Interventions: DRUG: Continous Intravenous Lidocaine Infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Long Term Follow-Up Results Of The Direct Nipple Ureteroneocystostomy Technique
Status: COMPLETED
Conditions: Vesicoureteral Reflux|Nipple Ureteroneocystostomy
Interventions: PROCEDURE: The Direct Nipple Ureteroneocystostomy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence
Status: NOT_YET_RECRUITING
Conditions: COVID-19|Fatigue|Distress Respiratory Syndrome|Cognitive Dysfunction|COVID-19 Recurrent|SARS CoV 2 Infection
Interventions: OTHER: Experimental tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Investigation of Soy and Estrogen
Status: COMPLETED
Conditions: Menopause|Hot Flashes
Interventions: DIETARY_SUPPLEMENT: Soy Phytoestrogen|DRUG: Estradiol|DRUG: Medroxyprogesterone Acetate (MPA)|DRUG: Soy Placebo|DRUG: MPA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Site Specific Mouth Disinfection With Commercial Oral Mouth Rinse With Traditional Oral Maouth Disinfection
Status: COMPLETED
Conditions: Oral Odor (Halitosis)|The Study Want to Know if Site Specific Mouth Rinsing With Oral Mouth Disinfectants Can be Better Than Paonoral Mouth Rinsing
Interventions: OTHER: traditional mouth rinsing and site-specific mouth rinsing (crossover)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgical Intervention in Bariatric Patients: Excess Weight Loss in the Morbidly Obese Following Gastric Plication
Status: TERMINATED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Gastric Plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H)
Status: RECRUITING
Conditions: High Risk Prostate Carcinoma
Interventions: RADIATION: Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS)
Status: COMPLETED
Conditions: Chronic Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: DRUG: Cernilton|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oxygen Consumption and Energy Expenditure During Spontaneous Breathing Trial.
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Automatic Tube Compensation plus CPAP|DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Finerenone (BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wii Aerobic Training in Inhalation-injury Children Post-thermal Burn
Status: COMPLETED
Conditions: Inhalation Injury
Interventions: OTHER: Wii aerobic training|OTHER: conservative chest care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Port Protectors for Prevention of CLABSIs in Respiratory Semi-intensive Care Unit
Status: COMPLETED
Conditions: Central Line-associated Bloodstream Infection (CLABSI)
Interventions: DEVICE: Training and retraining to GAVECELT "bundle" recommendations plus port protector|BEHAVIORAL: Training and retraining to GAVECELT "bundle" recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Effect of Herbal Medicine Nasal Irrigation on Treatment of Chronic Rhinitis and Sinusitis
Status: UNKNOWN
Conditions: Nasal Disease
Interventions: DEVICE: Taiwan Scientific" noninvasive blood pressure meter TS-0411|DEVICE: Meridian Energy Analysis Device(MEAD)|PROCEDURE: bacteria culture|PROCEDURE: nasopharyngoscopic examination|COMBINATION_PRODUCT: TCM nasal irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Total Body Skin Examination on Skin Cancer Detection
Status: COMPLETED
Conditions: Melanoma|Basal Cell Carcinoma|Squamous Cell Carcinoma|Merkel Cell Carcinoma|Skin Cancer
Interventions: OTHER: Inspection of covered areas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: OROS methylphenidate hydrochloride|DRUG: methylphenidate hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Trial for the Safety and Effect of MRGuided FUS Subthalamotomy for Medication Refractory Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: ExaBlate 4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of the Mosaic Ultra Device
Status: RECRUITING
Conditions: Skin Texture Disorder|Photoaging|Wrinkle|Scar|Stretch Mark|Acne Vulgaris|Hair Loss
Interventions: DEVICE: Mosaic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DIAMEL® Combined With Insulin in Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetic Foot|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: DIAMEL|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Self-Administered Maneuver to Relieve Symptoms Suggestive of Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: BEHAVIORAL: the Digital Repetitive Infrapubic Pressure maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Sonoguided Injection Corticosteroid and Hyaluronic Acid Injection in Treatment of Trigger Finger
Status: COMPLETED
Conditions: Trigger Finger
Interventions: DRUG: triamcinolone acetonide|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pergoveris FD and Liquid China BE Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pergoveris FD|DRUG: Pergoveris Liquid|DRUG: Gonal-f|DRUG: Luveris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Complications After Lower Third Molar Surgery
Status: UNKNOWN
Conditions: Postoperative Complications|Antibiotic Reaction|Antibiotic Side Effect|Antibiotic Resistant Infection|Antibiotic Resistant Strain|Infection, Bacterial|Infection, Laboratory
Interventions: DRUG: Moxifloxacin 400 mg Oral Tablet|DRUG: Cefixime 400 mg Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Egg-Banking and Ovo-donation
Status: COMPLETED
Conditions: Egg Banking
Interventions: OTHER: Vitrification of oocytes for IVF treatment|OTHER: Protocolary IVF treatment with fresh donor oocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)
Status: NOT_YET_RECRUITING
Conditions: Infertility of Uterine Origin
Interventions: PROCEDURE: Uterine Transplant from Deceased Donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Deep Vein Thrombosis - The EINSTEIN DVT Study
Status: COMPLETED
Conditions: Venous Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Enoxaparin followed by VKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Global Phase 3 Safety Study of 120 mcg rLP2086 Vaccine in Adolescents and Young Adults Aged 10 to 25 Years
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: rLP2086 vaccine|BIOLOGICAL: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eribulin Mesylate in Treating Patients With Recurrent Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Blood Pressure Measurement Using Samsung Smartwatch
Status: UNKNOWN
Conditions: Blood Pressure|Heart Rate
Interventions: OTHER: Calm measurement of blood pressure and heart rate (before physical activity)|OTHER: Physical activity|OTHER: Calm measurement of blood pressure and heart rate (after physical activity)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy Patients
Status: COMPLETED
Conditions: Transthyretin Amyloid Polyneuropathy (ATTR-PN)
Interventions: DRUG: tafamidis meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Parathyroid Hormone Injections Reverse Glucocorticoid-induced Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Parathyroid hormone (hPTH 1-34)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain
Status: COMPLETED
Conditions: Chronic Post-thoracotomy Pain
Interventions: DRUG: Ketamine|DRUG: ketamine free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Refitting Frequent Replacement Lens Wearers Into Clariti 1 Day And 1-Day Acuvue Moist Daily Disposable Spherical Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: somofilcon A|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine in Acute Decompensated Heart Failure II
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: High-dose furosemide|DRUG: Low-dose furosemide|DRUG: Low-dose furosemide combined with low-dose dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Agomelatine A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trauma Patients and Hypothermia in the Emergency Room: ReadyHeat® Versus Cotton Wool Blanket
Status: COMPLETED
Conditions: Hypothermia|Trauma
Interventions: DEVICE: ReadyHeat® blanket|DEVICE: Cotton wool blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swallowing Exercises for Nasopharyngeal Cancer After Radiation Therapy
Status: COMPLETED
Conditions: Nasopharyngeal Cancer|Dysphagia
Interventions: OTHER: effortful swallowing exercise|OTHER: Mendelsohn swallowing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-led Digital Health Lifestyle Intervention for a Low Income Community at Risk for Cardiovascular Diseases (MYCardio-PEER)
Status: RECRUITING
Conditions: Primary Prevention of Cardiovascular Diseases
Interventions: BEHAVIORAL: MYCardio-PEER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth
Status: COMPLETED
Conditions: Diarrhea|Stunting
Interventions: DIETARY_SUPPLEMENT: Standard MNP|DIETARY_SUPPLEMENT: High zinc, low iron MNP|DIETARY_SUPPLEMENT: High zinc, low/no iron on alternating days|DIETARY_SUPPLEMENT: Dispersible zinc supplement|DIETARY_SUPPLEMENT: Intermittent zinc supplement|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Digital Ulcer
Interventions: DRUG: Mesenchymal stromal cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Antiviral Activity and PK of MRD of BI 201335 in Chronic Hepatitis C Patients Both Treatment Naive and -Experienced
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI201335|DRUG: BI201335|DRUG: BI201335|DRUG: BI201335|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chromium Piccolinate in the Prevention of Weight Gain Induced by Serotonergic Medications Initiated on Psychiatric Inpatient Units.
Status: TERMINATED
Conditions: Weight Gain|Obesity
Interventions: DRUG: chromium piccolinate|DRUG: placebo for chromium piccolinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)
Status: RECRUITING
Conditions: Mucopolysaccharidosis (MPS)|Hunter Syndrome
Interventions: DRUG: ELAPRASE|DRUG: Rituximab|DRUG: Methotrexate|DRUG: Intravenous Immunoglobulin (IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infrared Lymphangiography as a Method of Sentinel Node Identification
Status: COMPLETED
Conditions: Melanoma|Sentinel Node
Interventions: DRUG: Indocyanine green|DRUG: Technetium99|DRUG: Methylene blue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC