pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Prospective Comparative Study of Induction of Labor With a Cervical Ripening Double Balloon vs Foley Catheter
Status: COMPLETED
Conditions: Induction of Labor|Cesarean|Endometritis
Interventions: DEVICE: Mechanical induction of labor|DEVICE: Double Balloon|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Skeletal Irradiation in Multiple Myeloma Before Second Autologous Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: RADIATION: Total Skeletal Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Carbohydrate Loading 2 Hours Before Gastroscopy on Gastric Residual Volume and Patient's Well-being Score
Status: COMPLETED
Conditions: Gastric Residual Volume|Upper Endoscopy
Interventions: OTHER: Plain water|OTHER: Carborie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Baduanjin Exercise Intervention on Quality of Life in Breast Cancer Survivors Receiving Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Breast Cancer Survivors Receiving Aromatase Inhibitor Therapy
Interventions: OTHER: Baduanjin exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Combination of Carboplatin, Eribulin Mesylate, and E7449 in BRCA-Related Cancers
Status: WITHDRAWN
Conditions: Cancer of the Breast
Interventions: DRUG: Carboplatin|DRUG: Eribulin|DRUG: E7449
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Care Teaching Sessions for Family Caregivers of Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: educational intervention|OTHER: questionnaire administration|PROCEDURE: end-of-life treatment/management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erector Spinae Plane Block With Two Different Volume for Open Heart Surgery
Status: UNKNOWN
Conditions: Sternotomy Pain
Interventions: PROCEDURE: Ultrasound-guided erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: V-Lap System For Wirelessly Measuring And Monitoring Left Atrial Pressure (LAP) In Patients With Advance Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: V-LAP™ SYSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Microsatellite Instability High
Interventions: DRUG: PD-1 inhibitor plus VEGF inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
Status: RECRUITING
Conditions: Warm Antibody Autoimmune Hemolytic Anemia
Interventions: DRUG: HMPL-523(300mg PO QD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Schizophrenia With Impulsivity
Status: COMPLETED
Conditions: Schizophrenia With Impulsivity
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Fatigue: A Pilot Study of Acupuncture and Patient Education for Breast Cancer Survivors
Status: COMPLETED
Conditions: Fatigue
Interventions: PROCEDURE: Acupuncture and patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Apatinib Mesylate Combined With Pemetrexed in the Treatment of Pretreated Advanced Non-squamous Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Nonsmall Cell Lung Cancer
Interventions: DRUG: Apatinib combined with pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: pitavastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: DRUG: Testosterone|DIETARY_SUPPLEMENT: Protein Supplement|OTHER: Placebo Injection|OTHER: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Asthma
Interventions: BEHAVIORAL: PEAKmAAP|BEHAVIORAL: PEAKmAAP-DS|BEHAVIORAL: NutriMap Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of IV Palo With IV Dexamethasone vs IV Palo for Prevention of Immediate & Delayed PONV
Status: COMPLETED
Conditions: PONV
Interventions: DRUG: Palonosetron only|DRUG: Palonosetron with Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Electromechanical Gait Trainer in Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: PROCEDURE: Device: Electromechanical gait trainer|PROCEDURE: Convetional control treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second Generation" Drug-Eluting Stents Implantation Followed by Six Versus Twelve-Month - Dual Antiplatelet Therapy
Status: TERMINATED
Conditions: Angina Pectoris|Silent Ischemia
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Glucocorticoid Taper Strategies for SLE-ITP
Status: ENROLLING_BY_INVITATION
Conditions: Lupus Erythematosus, Systemic|Purpura, Thrombocytopenic, Idiopathic|Glucocorticoids|Adverse Effect of Glucocorticoids
Interventions: PROCEDURE: rapid GCs taper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Test of the Time to Talk CARDIO (Creating a Real Dialogue In the Office) Program
Status: COMPLETED
Conditions: Cardiovascular Disease|Cardiovascular Risk Factors
Interventions: DEVICE: Time to Talk CARDIO website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraperitoneal Immune Checkpoint Inhibitor for Malignant Ascites
Status: ENROLLING_BY_INVITATION
Conditions: Malignant Ascites
Interventions: DRUG: Nivolumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Locally Advanced/Metastatic Soft Tissue Sarcoma or Advanced/Metastatic Malignant GIST
Status: COMPLETED
Conditions: Sarcoma|Malignant Gastrointestinal Stromal Tumor
Interventions: DRUG: Gemcitabine , Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Anastomosis Using MonoPlus® Suture
Status: WITHDRAWN
Conditions: Gastrointestinal Stromal Tumors|Gastrointestinal Neoplasms|Digestive System Neoplasm|Stomach Tumor|Small Intestine Tumor|Colon Tumor|Rectum Tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tourniquet vs. no Tourniquet During High Tibial Osteotomy
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Long-duration tourniquet|PROCEDURE: Short-duration tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of AIR OPTIX® COLORS Versus FRESHLOOK® COLORBLENDS
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lens with color|DEVICE: Phemfilcon A contact lens with color
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: ROMA (Reminiscence, Reality Orientation, Music and Art ) Therapy, Cognition, Depression and Behavioral Problems in the Population With Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: ROMA therapy(reminiacence therpy, orientation, music, and art)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Using Granules Dendrobii for the Treatment of Chronic Atrophic Gastritis
Status: RECRUITING
Conditions: Atrophic Gastritis
Interventions: DRUG: Granules Dendrobii|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Cholangiocarcinoma|Liver Cancer|Colorectal Adenocarcinoma|Pancreatic Cancer|Gastric Cancer|Esophageal Adenocarcinoma|Gastroesophageal Junction
Interventions: DRUG: Cabotamig (ARB202)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD-tDCS Over the dACC in High Trait Impulsivity
Status: COMPLETED
Conditions: Impulsive Behavior
Interventions: DEVICE: Active High Definition transcranial Direct Current Stimulation (HD-tDCS)|DEVICE: Sham High Definition transcranial Direct Current Stimulation (HD-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreas Cancer|Ampullary Cancer|Pancreas Neuroendocrine Tumor|Pancreatitis|Distal Extrahepatic Cholangiocarcinoma|Duodenal Cancer
Interventions: DRUG: Placebo|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intravenous Nutrition and Epidural Analgesia on Protein Loss After Surgery
Status: COMPLETED
Conditions: Postoperative Protein Catabolism
Interventions: OTHER: Intravenous nutrition with glucose and amino acids|OTHER: Intravenous nutrition with glucose and amino acids.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Binaural Beats on Pain, Anxiety, and Procedure Tolerance in Patients Undergoing Colonoscopy Without Sedation
Status: COMPLETED
Conditions: Anxiety State|Patient Satisfaction|Tolerance
Interventions: OTHER: binaural music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Gut Butyrate and Blood Pressure in African Americans
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Sodium Butyrate 5 mmol|DRUG: Sodium Butyrate 80 mmol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Role of Double Cuffed PTFE Arteriovenous Grafts in Enhancing Long-term Patency in Hemodialysis Patients (Extended Poly Tetra Fluoro Ethylene)
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Double vein cuffed ePTFE graft both at the inflow and outflow ends|PROCEDURE: single vein cuffed eTFE graft both at the inflow and outflow ends|PROCEDURE: ePTFE graft without any cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Antiviral and Aspirin Treatment in Liver Cancer After Radical Surgery
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Recurrence
Interventions: DRUG: Aspirin|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Sensory Processing Anomalies
Status: RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder|Sensory Processing Disorder
Interventions: BEHAVIORAL: Discrimination Acuity test|DIAGNOSTIC_TEST: Transiently Evoked Otoacoustic Emission|OTHER: Questionnaires|BEHAVIORAL: Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V)|DIAGNOSTIC_TEST: Clinical tests of ASD|OTHER: Electroencephalography (EEG) with auditory or vibrotactile stimuli|DIAGNOSTIC_TEST: Clinical tests of ADHD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketoprofen in Transfersome Compared to Oral Celecoxib and Placebo for Pain Associated With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Ketoprofen in Transfersome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Plane Block vs Intrathecal Morphine
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Ultrasound Guided Erector Spinae Plane Block|DRUG: Intra thecal morphine.|DRUG: General anesthesia using intravenous fentanyl (1µgm/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: High Calorie Formula Intervention on Weight, Length Increment, Total Lymphocyte Counts, TNF-alpha and IGF-1 in Failure to Thrive Children
Status: COMPLETED
Conditions: Failure to Thrive|Infection, Bacterial|Growth Faltering
Interventions: DIETARY_SUPPLEMENT: high calorie formula (oral nutritional supplement/ONS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY2157299 in Participants With Unresectable Hepatocellular Cancer (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: LY2157299|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Telemonitoring Program on the Rate of Hospitalizations for Worsening of Cardio-respiratory Symptoms in COPD Patients Treated at Home by Long-term Non-invasive Ventilation (NIV)
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Telemonitoring of daily parameters recorded by NIV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases
Status: TERMINATED
Conditions: Inherited Metabolic Diseases|Lysosomal Storage Disorders|Peroxisomal Storage Diseases|Inborn Errors of Metabolism|Mucopolysaccharidosis
Interventions: BIOLOGICAL: ALD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Effect of Transcranial Alternating Current Stimulation (tACS) on Disorder of Consciousness (DOC)
Status: RECRUITING
Conditions: Disorders of Consciousness
Interventions: DEVICE: high definition-transcranial alternating current stimulation|DEVICE: sham transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma|Acute Lymphoblastic Leukemia
Interventions: DRUG: GNC-038
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid vs. Combination With Fractional Carbon Dioxide Laser in Melasma
Status: UNKNOWN
Conditions: Melasma
Interventions: DEVICE: Fractional CO2 laser|DRUG: Tranexamic acid intradermal microinjections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial on Intraoperative Radiotherapy Full Dose Vs External Radiotherapy
Status: COMPLETED
Conditions: Carcinoma Breast
Interventions: RADIATION: external fractionated radiotherapy|RADIATION: intraoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pulse-Based Foods Combined With Exercise for Improving Components of the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Aerobic exercise training|DIETARY_SUPPLEMENT: pulse based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: When Cooling a Patient After Cardiac Arrest, Does Use of a Neuromuscular Blocking Agent Make Your Job Easier?
Status: UNKNOWN
Conditions: Postcardiac Arrest Therapeutic Hypothermia
Interventions: DRUG: Cisatracurium infusion|DRUG: Cisatracurium prn bolus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Variable Dead Space Rebreathing Device to Treat Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Sleep Apnea, Central
Interventions: DEVICE: Smart CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
Status: ENROLLING_BY_INVITATION
Conditions: Solid Tumors|Hematologic Malignancy|Gastrointestinal Cancer|Liver Cancer|Pancreatic Cancer|Melanoma|Pre-Malignancy|Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot-Assisted Therapy (RT)|DEVICE: Robot & Task-Oriented Training (RT-TOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Response to Single Dose of Pregabalin in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Pregabalin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epothilone (Ixabepilone) Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Cancer|Breast Cancer
Interventions: DRUG: Ixabepilone + Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment Effect of Endoscopic Evacuation Versus Suboccipital Craniotomy for Spontaneous Intracerebellar Hemorrhage.
Status: RECRUITING
Conditions: Posterior Fossa Hemorrhage
Interventions: PROCEDURE: Endoscopic surgery|PROCEDURE: Suboccipital craniotomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: saxagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Objective Brain Function Assessment of mTBI/Concussion in High School Athletes
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Concussion, Brain|Concussion, Mild|Concussion, Intermediate|Concussion, Severe
Interventions: DEVICE: BrainScope Ahead 200iD|DEVICE: Advanced MRI Neuroimaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexamethasone Versus Dexmedetomidine
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: dexamethasone 8 mg|DRUG: dexmedetomidine 80 µg|DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thunder-Fire Moxibustion Therapy for Chronic Fatigue Syndrome on Shenque Acupoint: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome
Interventions: OTHER: thunder-fire moxibustion therapy|OTHER: common moxa-stick moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Intravenous Anesthesia|Inhalational Anesthesia|Surgical Stress Response|Target-controlled Infusion
Interventions: DRUG: Sevoflurane|DRUG: Target Controlled Infusion|DRUG: Target Controlled Infusion and lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors
Status: COMPLETED
Conditions: Brain Tumor|Brain Cancer|Cns Cancer|Cognitive Dysfunction
Interventions: OTHER: donepezil and questionaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine,Vincristine and Cisplatin as Second Line Combination Therapy in Patients With Sarcoma
Status: UNKNOWN
Conditions: Sarcoma|Chemotherapy
Interventions: DRUG: GVP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Olmesartan as an add-on to Amlodipine in Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: olmesartan medoxomil|DRUG: amlodipine|DRUG: hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: Subetta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: placebo|DRUG: Histamine|DRUG: AllerT1|DRUG: AllerT2|DRUG: AllerT3|DRUG: AllerT4|DRUG: AllerT5|DRUG: mix of AllerT1-T2-T3|DRUG: mix of AllerT4-T5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia
Status: COMPLETED
Conditions: Cytopaenia
Interventions: DRUG: Eltrombopag 12.5 mg|DRUG: Eltrombopag 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of EZ-Ject Injector a Pain-Free Subcutaneous Automatic Injection in Healthy Volunteers
Status: SUSPENDED
Conditions: Healthy
Interventions: DEVICE: painless subcutaneous injection by EZ-Ject Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effectiveness of 8 Week Multicomponent Exercise Program in Older Adults With Frailty and Cognitive Impairment
Status: RECRUITING
Conditions: Old Age; Debility
Interventions: OTHER: Multicomponent exercise program focused in elderly.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)
Status: COMPLETED
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: Seladelpar 10 mg|DRUG: Placebo|DRUG: Seladelpar 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo
Status: COMPLETED
Conditions: Endometrioma
Interventions: DRUG: Desogestrel Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digoxin for Congenital Erythrocytosis Due to Up-Regulated Hypoxia Sensing
Status: WITHDRAWN
Conditions: Polycythemia; Familial|Erythrocytosis; Familial|VHL Gene Mutation|HIF-2alpha Erythrocytosis|PHD2 Erythrocytosis|Chuvash Erythrocytosis
Interventions: DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.
Status: RECRUITING
Conditions: Dental Caries
Interventions: DEVICE: Hall Technique (HT)|DEVICE: Modified Hall Technique (MHT)|DEVICE: Conventional Technique (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Morbidity After Endotracheal Intubation - Endoflex-tube Versus Use of Stylet
Status: COMPLETED
Conditions: Intubation Complication|Anaesthesia
Interventions: DEVICE: Endoflex tube|DEVICE: Polyvinyl chloride endotracheal tube with a stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Reduce Duration of Antibiotic Therapy in Haematological Patients With Fever and Neutropenia
Status: COMPLETED
Conditions: Febrile Neutropenia
Interventions: DRUG: Empirical antimicrobial treatment discontinuation|DRUG: Standard empirical antimicrobial treatment discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)
Status: COMPLETED
Conditions: Hospital-Acquired Bacterial Pneumonia|Ventilator-Associated Bacterial Pneumonia
Interventions: DRUG: IMI/REL FDC|DRUG: PIP/TAZ FDC|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Hemostatic Efficacy of Fibrin Sealant Vapor Heated, Solvent/Detergent Treated (FS VH S/D) Compared With Currently Licensed TISSEEL VH Fibrin Sealant in Subjects Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery Requiring Cardiopulmonary Bypass and Median Sternotomy|Cardiopulmonary Bypass|Sternotomy
Interventions: DRUG: Fibrin Sealant Vapor Heated Solvent/Detergent Treated (FS VH S/D)|DRUG: TISSEEL VH fibrin sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Prednisone to Decrease Pegylated Interferon Beta-1a Side Effects
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Plegridy|DRUG: Prednisone|DRUG: Tylenol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Minus Anthracycline or Short-Term Versus Epirubicin and Cyclophosphamide Followed by Paclitaxel Regimen for Adjuvant Breast Cancer Therapy
Status: COMPLETED
Conditions: Primary Breast Cancer
Interventions: DRUG: Docetaxel Cyclophosphamide|DRUG: Cyclophosphamide Fluorouracil Epirubicin Docetaxel|DRUG: Epirubicin Cyclophosphamide Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Antimicrobials on the Altered Skin Flora in Arsenical Keratosis
Status: UNKNOWN
Conditions: Keratotic Nodular Size
Interventions: DRUG: Tetracycline|DRUG: Clotrimazole|DRUG: Tetracycline and Clotrimazole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin/CPT-11 for Extensive Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Irinotecan (CPT-11)|DRUG: Oxaliplatin (Eloxatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Using Endotracheal Tube Introducer for Intubation During Mechanical Chest Compressions in a Manikin
Status: UNKNOWN
Conditions: Intubation, Intratracheal|Advanced Cardiac Life Support
Interventions: DEVICE: Endotracheal tube introducer|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre-Lens Tear Film Performance of Silicone Hydrogel Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Delefilcon A contact lens|DEVICE: Narafilcon A contact lens|DEVICE: Filcon II 3 contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TCM Capsules Lian Hua Qing Wen Jiao Nang in Mild COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: TCM intervention|OTHER: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and GBS Colonization in Pregnancy
Status: SUSPENDED
Conditions: GBS Rectovaginal Colonization|Neonatal Sepsis
Interventions: DIETARY_SUPPLEMENT: Respecta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Simvastatin|DRUG: acetylsalicylic acid (ASA)|DRUG: omefas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thalidomide in Suppression of the Systemic Inflammatory Response Syndrome in Hemodialysis Patients
Status: TERMINATED
Conditions: Hypoalbuminemia
Interventions: DRUG: Thalidomide|OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of First Line Treatment With Tarceva (Erlotinib) in Combination With Gemcitabine in Patients With Locally Advanced Unresectable or Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: erlotinib [Tarceva]|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DUTCH Weight Control in Atrial Fibrillation Study
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Obesity|Weight Loss
Interventions: DRUG: Semaglutide 3.2 MG/ML|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Pain Control in Opioid Tolerant Patients: Fentanyl Challenge Protocol Versus Standard of Care
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis|Hypertension, Pulmonary
Interventions: DRUG: Sildenafil Citrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Neoplasms|Cancer|Tumors
Interventions: DRUG: TAS-102|DRUG: Temozolomide|DRUG: Filgrastim|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Impact of Real-Time Continuous Glucose Monitoring on People Presenting With Severe Hypoglycaemia
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia Unawareness|Hypoglycemia
Interventions: DEVICE: Dexcom G6 CGM|DEVICE: Tandem t:slim X2 Insulin Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (IMC-1121B) in Combination With Eribulin Versus Eribulin Alone in Participants With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Ramucirumab (IMC-1121B)|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Higher Protein Dosing in Critically Ill Patients: A Multicenter Randomized Trial
Status: WITHDRAWN
Conditions: Nutritional Disorder|Critical Illness|Malnutrition|Frailty|Sarcopenia
Interventions: DRUG: OLIMEL 7,6%E / PeriOLIMEL 2,5%E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Tools of the Mind for Enhancing Self-Control in Preschoolers
Status: COMPLETED
Conditions: Self Control|Early Childhood Development
Interventions: BEHAVIORAL: Tools of the Mind (TOM)|BEHAVIORAL: Playing to Learn (PTL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Optimal Duration of a Group-based Online Behavioral Weight Loss Program
Status: WITHDRAWN
Conditions: Obesity and Overweight
Interventions: BEHAVIORAL: Four Month Duration Online Behavioral Weight Loss Program|BEHAVIORAL: Six Month Duration Online Behavioral Weight Loss Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduce Stress Associated With Needle Aspiration, in Voluntary and Replacement Blood Donors
Status: UNKNOWN
Conditions: Stress
Interventions: DEVICE: Use of virtual reality lenses, with relaxing audio-visual contents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy (PDT) With Methyl Aminolevulinate (MAL) Cream in Patients With Skin Type V or IV With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Methyl aminolevulinate (MAL) PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway
Status: COMPLETED
Conditions: Intraoperative Ventilation
Interventions: PROCEDURE: Spontaneous ventilation|DEVICE: Pressure support Ventilation|DEVICE: Pressure control ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Prevalence of Small Airways Dysfunction In COPD Patients and The Impact on COPD Control
Status: UNKNOWN
Conditions: COPD|Small Airway Disease
Interventions: DIAGNOSTIC_TEST: Impulse oscillometry|DIAGNOSTIC_TEST: Spirometric pulmonary function test|DIAGNOSTIC_TEST: Fractional exhaled nitric oxide (FENO) test|DIAGNOSTIC_TEST: Thorax Computed Tomography|DIAGNOSTIC_TEST: Chest X Ray|DIAGNOSTIC_TEST: Blood eosinophil level|OTHER: CAT|OTHER: mMRC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open Label, Pilot Study of Darunavir Boosted by Cobicistat in Combination With Rilpivirine to Treat HIV+ Naïve Subjects
Status: UNKNOWN
Conditions: HIV Positive
Interventions: DRUG: darunavir/cobicistat|DRUG: rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae Vaccines
Interventions: BIOLOGICAL: Synflorix (3-Dose)|BIOLOGICAL: Synflorix (2-Dose)|BIOLOGICAL: Synflorix (Single Dose)|BIOLOGICAL: Prevenar 13 (Single Dose)|BIOLOGICAL: Prevenar 13 (2-Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extended-Release Form of Clonidine as an Anti-Manic Agent: An Add-on, Open-Label Study
Status: TERMINATED
Conditions: Bipolar Disorder, Mania
Interventions: DRUG: extended-release clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists
Status: RECRUITING
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: Sirolimus|DRUG: Cyclophosphamide|DRUG: Alemtuzumab|DRUG: Busulfan|BIOLOGICAL: Pheripheral blood stem cells|DRUG: Emapalumab-Izsg|DRUG: Tociluzumab|DRUG: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Incisional Hernia by Mesh Augmentation After Midline Laparotomy for Aortic Aneurysm Treatment
Status: COMPLETED
Conditions: Aortic Aneurysm
Interventions: PROCEDURE: Conventional laparotomy closure|PROCEDURE: Laparotomy closure with mesh augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Group Drumming (IGD) in Hospital Experience of Patients Undergoing Hematopoietic Stem Cell Transplant - A Pilot Study
Status: COMPLETED
Conditions: Hematopoietic Cell Transplant
Interventions: BEHAVIORAL: interactive group drumming sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of 9MW2821 in the Treatment of High-risk Non-muscle-invasive Bladder Cancer (NMIBC)
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: 9MW2821
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study Between UIC201601 and UIC201602
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: UIC201602 and co-administration of UIC201601 and UIC201602|DRUG: UIC201601 and co-administration of UIC201601 and UIC201602
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Yoga in Controlling Symptoms and Reducing Stress in Women With Ovarian Cancer or Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Fatigue|Ovarian Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: yoga therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating LINFU™: A Noninvasive Method for Collecting Pancreatic Cells for the Early Detection of Pancreatic Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: COMBINATION_PRODUCT: LINFU™ Technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doravirine Versus Integrase Inhibitors on Backbone of Emtricitabine and Tenofovir Alafenamide in HIV
Status: RECRUITING
Conditions: HIV I Infection|Cardiovascular Risk Factor|Lipid Metabolism Disorders
Interventions: DRUG: Doravirine 100 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of the Combination of AZD2014 and Weekly Paclitaxel.
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: AZD2014 3 on/4 off & weekly paclitaxel|DRUG: AZD2014 2 on/5 off & weekly paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and PD Crossover Study After Single Dose, Intravenous Administration of Two Epoetin Alfa, Human Recombinant Epoetin and Eprex, in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ejection Fraction of Normal Gall Bladder on Ultrasonography in Patients With Biliary Colic: Is it a Predictor of Cholecystectomy?
Status: NOT_YET_RECRUITING
Conditions: Gall Bladder Pain|Hepatobiliary Iminodiacetic Acid|Acalculous Cholecystitis
Interventions: PROCEDURE: cholecystectomy|DRUG: Antispasmodic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Extended Follow-up of Women Who Received One, Two, and Three Doses of the HPV Vaccine in the Costa Rica Vaccine Trial (CVT), ESCUDDO-CVT Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus Infection|Human Papillomavirus-Related Malignant Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-operative Treatment of Acute Achilles Tendon Rupture Using Dynamic Rehabilitation. Influence of Early Weight-bearing Compared With Non-weight-bearing
Status: COMPLETED
Conditions: Acute Achilles Tendon Rupture
Interventions: PROCEDURE: Early weight-bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Two Formulations of Escitalopram
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Escitalopram|DRUG: Escitalopram|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A
Status: ACTIVE_NOT_RECRUITING
Conditions: Fanconi Anemia Complementation Group A
Interventions: BIOLOGICAL: RP-L102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT