pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Text Message Intervention for Alcohol Use and Sexual Violence in College Students
Status: COMPLETED
Conditions: Alcohol Use, Unspecified|Sexual Violence|Sexual Assault
Interventions: BEHAVIORAL: sexual violence and alcohol use harm reduction text message content|BEHAVIORAL: alcohol use reduction content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Ketamine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nateglinide|DRUG: Nateglinide/Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Epicardial Pulmonary Vein Isolation in Patients With Atrial Fibrillation Undergoing Elective Cardiac Surgery
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Epicardial pulmonary vein isolation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cetaphil Advanced Usage to Control Light to Moderate Atopic Dermatitis, in Attempt to Reduce the Necessity of Topic Corticoids Application
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: OTHER: Emollient - Cetaphil Advanced
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the Southern Hemisphere 2015 Season
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza subunit vaccine Influvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Glucose-Dependent Insulinotropic Polypeptide in the Pathological Glucose Homeostasis Of Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia
Interventions: DRUG: GIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
Status: RECRUITING
Conditions: Ventral Hernia|Hernia|Herniorrhaphy|Abdominal Wall|Postoperative Period|Physical Therapy Modalities
Interventions: OTHER: Supervised Physical Therapy|OTHER: Post-operative Precautions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Procedural Awareness of Knee Injections for Osteoarthritis on Patient Perceptions of Effectiveness
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Platelet-rich plasma (PRP)|BEHAVIORAL: Viewing of preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Depth and Duration of Anesthesia From Heated Lidocaine/Tetracaine (Synera®) Patches Compared With 5% Lidocaine (Lidoderm®) Patches Applied to Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Heated Lidocaine/Tetracaine Patch|DRUG: 5% Lidocaine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma
Status: COMPLETED
Conditions: Metastatic Carcinoma in the Adrenal Cortex|Stage III Adrenal Cortex Carcinoma AJCC v8|Stage IV Adrenal Cortex Carcinoma AJCC v8|Unresectable Adrenal Cortex Carcinoma
Interventions: DRUG: Cabozantinib|OTHER: Pharmacogenomic Study|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib and Temozolomide in Patients Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioma, Malignant
Interventions: DRUG: Temodal|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell and Islet Co-transplantation
Status: COMPLETED
Conditions: Chronic Pancreatitis|Diabetes
Interventions: BIOLOGICAL: autologous mesenchymal stromal cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Comparing Linjeta Versus Humalog in Pumps: Effect on Postprandial Blood Sugars.
Status: WITHDRAWN
Conditions: Diabetes Mellitus
Interventions: DRUG: LINjeta U-100 Insulin|DRUG: Humalog U-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Study of Farletuzumab to Treat Resectable, Non-functioning Pituitary Adenomas
Status: WITHDRAWN
Conditions: Resectable, Non-functioning Pituitary Adenoma
Interventions: DRUG: Farletuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of Surgical Material for Nasal Septoplasty
Status: UNKNOWN
Conditions: Septal Deformity|Nasal Obstruction
Interventions: PROCEDURE: Nasal septoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of PH-10 for Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PH-10 (0.002% Rose Bengal)|DRUG: PH-10 (0.005% Rose Bengal)|DRUG: PH-10 (0.01% Rose Bengal)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Treatment for Recurrent Clostridium Difficile
Status: ACTIVE_NOT_RECRUITING
Conditions: Clostridium|Difficile|Fidaxomicin|Vancomycin
Interventions: DRUG: Fidaxomicin|DRUG: Vancomycin with Taper/Pulse|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of β-cryptoxanthin (β-Cx), Plant Sterols and Galactooligosaccharides on Systemic and Gastrointestinal Markers
Status: UNKNOWN
Conditions: Hypercholesterolemia|Osteoporosis|Postmenopausal Disorder
Interventions: DIETARY_SUPPLEMENT: β-Cx plus PS plus GOS|DIETARY_SUPPLEMENT: β-Cx plus PS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Lactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant)
Status: ENROLLING_BY_INVITATION
Conditions: ICD10 Code L40.9 for Psoriasis
Interventions: DRUG: Betamethasone dipropionate 0.05%|DRUG: Tapinarof
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Identification of Multiple Pulmonary Diseases Using Volatile Organic Compounds Biomarkers in Human Exhaled Breath
Status: RECRUITING
Conditions: Lung Cancer|Lung Infection|COPD|Bronchitis|Pulmonary Fibrosis|Pulmonary Embolism|Pulmonary Arterial Hypertension|Pulmonary Tuberculosis|Pulmonary Abscess|Emphysema|Lung Injury|Cystic Fibrosis of the Lung|Bronchial Asthma|Bronchiectasis|Interstitial Lung Disease|Preserved Ratio Impaired Spirometry
Interventions: OTHER: Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robot-assisted Cognitive Training for Lonely Older Adults With Mild Cognitive Impairment (MCI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Change|Cognitive Impairment, Mild|Aging
Interventions: BEHAVIORAL: Piano Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Dose-finding Study of MAL and HAL Photodynamic Therapy of Cervical Premalignant Lesions.
Status: COMPLETED
Conditions: Cervical Dysplasia
Interventions: DRUG: methyl aminolevulinate (MAL) and hexaminolevulinate (HAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Safety and Pharmacokinetics of Tavaborole Topical Solution for the Treatment of Fungal Disease of the Toenail in Children and Adolescents
Status: COMPLETED
Conditions: Onychomycosis|Tinea Unguium
Interventions: DRUG: Tavaborole 5% Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms.
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic|Lupus Erythematosus, Cutaneous
Interventions: DRUG: Placebo|DRUG: PF-06823859
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study of Evolocumab (AMG 145) in Adults With Hyperlipidemia and Mixed Dyslipidemia
Status: COMPLETED
Conditions: Hyperlipidemia and Mixed Dyslipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone Implant on Optic Disc
Status: COMPLETED
Conditions: Glaucoma and Ocular Hypertension|Diabetic Macular Edema|Intravenous Drug Usage|Optic Disk Disorders
Interventions: PROCEDURE: intravitreal dexamethasone implant application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia
Status: WITHDRAWN
Conditions: Solid Tumour
Interventions: BIOLOGICAL: MVC-101|BIOLOGICAL: Nivolumab|COMBINATION_PRODUCT: MVC-101 + Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Neurostimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: low-intensity transcranial electrical stimulation|PROCEDURE: transcranial ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Study of Duodopa (Levodopa/Carbidopa) in Advanced Parkinson's: Health Outcomes & Net Economic Impact
Status: COMPLETED
Conditions: Advanced Idiopathic Parkinson's Disease
Interventions: DRUG: Levodopa-carbidopa intestinal gel (LCIG)|DEVICE: CADD-Legacy® 1400 ambulatory infusion pump|DEVICE: percutaneous endoscopic gastrostomy tube (PEG tube)|DEVICE: jejunal extension tube (J-tube)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serplulimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Treatment Esophageal Cancer in Old Age
Status: RECRUITING
Conditions: Esophageal Carcinoma
Interventions: DRUG: Serplulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Programs After Achilles Tendon Rupture
Status: COMPLETED
Conditions: Rupture of Achilles Tendon|Immobility Response, Tonic|Rupture, Spontaneous
Interventions: OTHER: Traditional Immobilization|OTHER: Early Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PATIENT VOICES Integration of Systematic Assessment of Patient Reported Outcomes Within Clinical Oncology Practice
Status: UNKNOWN
Conditions: Neoplasms|Symptoms and Signs|Psychological Distress|Satisfaction, Consumer|Quality of Life
Interventions: BEHAVIORAL: Systematic ePROMs Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Therapeutic Measures in Dental Caries Reduction in Children With Primary Dentition From Medellín City
Status: COMPLETED
Conditions: Dental Decay
Interventions: PROCEDURE: topical fluoride varnish application.|PROCEDURE: professional cleaning|PROCEDURE: No fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia?
Status: COMPLETED
Conditions: Pain|Secondary Hyperalgesia|Healthy Volunteers|Magnetic Resonance Imaging
Interventions: DEVICE: MRI-scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Non Inferiority of Non Capsular Suture in Femoroacetabular Impingement Arthroscopic Treatment
Status: COMPLETED
Conditions: Femoral Acetabular Impingement
Interventions: PROCEDURE: Hip arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Antegrade Arterial and Portal Flushing Versus Portal Flushing Only in LDLT
Status: COMPLETED
Conditions: Biliary Complications|Graft Function, Delayed
Interventions: PROCEDURE: Arterial Flushing|PROCEDURE: Portal Flushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Machine Learning-Based Mobile Application on Physical Activity in Overweight and Obese Women
Status: NOT_YET_RECRUITING
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: Individualized physical activity management system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Atraumatic Rotator Cuff Rupture in Elderly Patients
Status: COMPLETED
Conditions: Atraumatic Rotator Cuff Rupture
Interventions: PROCEDURE: physiotherapy|PROCEDURE: acromioplasty|PROCEDURE: acromioplasty and rotator cuff reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ChiCGB vs BEAM in High-risk or R/R Lymphomas
Status: RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse|Lymphoma, T-Cell
Interventions: DRUG: Chidamide|DRUG: Cladribine|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan|PROCEDURE: Autologous hematopoietic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide to Overcome Lenalidomide Resistance After Autologous Hematopoietic Stem Cell Transplantation (HCT)
Status: TERMINATED
Conditions: Myeloma
Interventions: DRUG: Thalidomide|DRUG: Lenalidomide|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study - Macroflux Parathyroid Hormone (PTH) in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: teriparatide|DRUG: teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Integrated E-TRANS (Fentanyl) System and Separated (Two-Part) E-TRANS (Fentanyl) System
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Separated (Two Part) E-TRANS (fentanyl HCl) System; Integrated E-TRANS (fentanyl HCl) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of CLBS12 in Patients With Critical Limb Ischemia (CLI)
Status: COMPLETED
Conditions: Critical Limb Ischemia|Buerger Disease|Thromboangiitis Obliterans|Atherosclerosis Obliterans
Interventions: BIOLOGICAL: CLBS12|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Viusid in Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Viusid|OTHER: Hypocaloric Diet with controlled exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload
Status: TERMINATED
Conditions: Transfusion-dependent β-thalassemia Patients|Cardiac Iron Overload
Interventions: DRUG: Deferasirox|DRUG: Deferoxamine (DFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Multiple Endocrine Neoplasia Type 1|Pancreatic Neuroendocrine Carcinoma
Interventions: RADIATION: Computed Tomography Perfusion Imaging|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Ziv-Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV
Status: COMPLETED
Conditions: Lidocaine|Dexmedetomidine|Nausea and Vomiting, Postoperative
Interventions: DRUG: lidocaine and dexmedetomidine IV|DRUG: saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease
Status: ENROLLING_BY_INVITATION
Conditions: IBD|Infliximab|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: Switch to SC CT-P13.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphoid Leukemia
Interventions: BIOLOGICAL: Ibrutinib|BIOLOGICAL: Venetoclax|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Ezetimibe|DRUG: Placebo for Ezetimibe|DRUG: Placebo for Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab in Combination With Chemotherapy and Antiangiogenic Agents in Patients With Non-Small Cell Lung Cancer After Failure of Immunotherapy (PD-1/L1 Inhibitors)
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer Recurrent
Interventions: DRUG: Toripalimab, Anlotinib and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 5 Treatment Period Pharmacokinetic Study Evaluating Dose Proportionality and Food Effects of Diazoxide Choline Controlled-Release Tablet (DCCR)
Status: UNKNOWN
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Diazoxide choline controlled-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nutritional Supplement Capsule Containing Curcumin, Green Tea Extract, Polygonum Cuspidatum Extract, and Soybean Extract in Healthy Participants
Status: COMPLETED
Conditions: Healthy, no Evidence of Disease
Interventions: DIETARY_SUPPLEMENT: curcumin/green tea extract/Polygonum cuspidatum extract/soybean extract capsule|GENETIC: electrophoretic mobility shift assay|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Status: COMPLETED
Conditions: To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Interventions: DRUG: sublingual Misoprostol|DRUG: Intrauterine Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn Disease
Status: UNKNOWN
Conditions: Ulcerative Colitis|Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Boulardii|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Sacroiliac Fusion Versus Fusion to the Sacrum for Degenerative Disease of the Lumbar Spine
Status: UNKNOWN
Conditions: Degeneration Spine
Interventions: PROCEDURE: S2alar-iliac screws|PROCEDURE: S1 screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Macro and Microcirculatory Arterial Condition of the Upper Limb in Insufficiently Renal Patients
Status: RECRUITING
Conditions: Arteriopathy Upper Limb|Renal Insufficiency|Digital Pressure
Interventions: OTHER: evaluation of arterial anomalies in upper limbs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Planned Semi-Elective Lung Tx Study
Status: RECRUITING
Conditions: To Compare Lung Transplant Outcomes Between Study Patients and Standard Patients Who Have Already Undergone Lung Transplantation by Conventional Procedures|Lung Transplant
Interventions: PROCEDURE: Experimental: Preserving of Donor Lungs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Blood Sampling Functionality of Extended Dwell Catheters
Status: COMPLETED
Conditions: IV Catheter-Related Infection or Complication|Vascular Access Complication|Peripheral Venous Access
Interventions: DEVICE: Extended dwell catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE
Status: RECRUITING
Conditions: Labor
Interventions: DRUG: Ephedrine|DRUG: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuroprotection in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic
Interventions: DRUG: Hydrogen|DRUG: Minocycline|OTHER: Placebo Hydrogen|OTHER: Placebo Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N\L Ratio Versus L\A Ratio as a Predictor of Morbidity and Mortality in Sepsis and Septic Shock
Status: RECRUITING
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: Neutrophil/Lymphocyte ratio and lactate/ albumin ratio will be measured in all patients.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physiatrist Ergonomic Intervention on Work Related Musculoskeletal Pain in Surgeons
Status: ENROLLING_BY_INVITATION
Conditions: Musculoskeletal Pain|Work Related Stress|Quality of Life|Grip
Interventions: OTHER: Educational video on ergonomics|OTHER: Verbal physical therapy coaching sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Soft Tissue Responses Around Nanostructured Calcium-phosphate-coated Implant Abutments on Dental Implants: Histological, Genetic and Clinical Evaluation in Smokers and Non-smokers.
Status: COMPLETED
Conditions: Missing Several Teeth|Minimum of 2 Dental Implants Needed
Interventions: PROCEDURE: normal healing abutment|PROCEDURE: nano-structured healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Nateglinide and Acarbose on the Post-Prandial Glucose Control in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: nateglinide|DRUG: acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Intensity Modulated Chemoradiotherapy to Treat Locally Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Stage III Non-Small Cell Lung Cancer
Interventions: RADIATION: Dose escalated, accelerated, hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Neuropathy Rapid Screening Test in Turkish Patients With Type 2 Diabetes: Sudoscan
Status: COMPLETED
Conditions: Neuropathy Autonomic|Cardiac Autonomic Neuropathy|Type2Diabetes|Diabetic Neuropathy Peripheral|Diabetic Neuropathies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HepNet Acute HCV IV - LDV/SOF FDC in Acute Genotype 1 Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Acute Hepatitis C
Interventions: DRUG: LDV/SOF FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Safety, Tolerability And Pharmacokinetics (PK) Of RO7223280 Following Intravenous Administration In Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: RO7223280
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients
Status: WITHDRAWN
Conditions: Delirium
Interventions: DRUG: Sevoflurane|DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vascular Structure in Elderly Using High-frequency Ultrasound and Construction of a Multimodal Risk Assessment System for Cardiovascular Diseases: a Multicenter Study
Status: NOT_YET_RECRUITING
Conditions: Atherosclerosis|Stroke|Coronary Disease
Interventions: OTHER: High-frequency carotid arteries ultrasound, CCTA, Cranial MRA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Sealing Dental Caries
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Non-invasive resin based caries sealing|PROCEDURE: Invasive resin based restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Safety And Efficacy Of PF-06700841 In Subjects With Moderate To Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: PF-06700841|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hemodynamic Changes Caused by Different Pneumoperitoneum Pressure Ranges (10-12 mmHg and 13- 15 mmHg ) on Cerebral Oxygenation (With a Non-invasive Technique, Near Infrared Spectroscopy (NIRS) ) in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Pneumoperitoneum
Interventions: PROCEDURE: Low pneumoperitoneum (10-12 mmHg) pressure range group|PROCEDURE: High pneumoperitoneum (13-15 mmHg) pressure range group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure
Status: COMPLETED
Conditions: Intracranial Hypertension
Interventions: DRUG: 20% mannitol|DRUG: 7.45% hypertonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effects of Diet and Physical Activity on Esport Performance
Status: NOT_YET_RECRUITING
Conditions: Sports Physical Therapy|Dietary Habits|Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: Low glycaemic index|DIETARY_SUPPLEMENT: High glycaemic index|BEHAVIORAL: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Tacrolimus Versus Hydrocortisone in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic|Dermatitis
Interventions: DRUG: Tacrolimus|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Meats and Potatoes Intake.
Status: COMPLETED
Conditions: Biomarkers of Food Intake in Healthy Subjects
Interventions: OTHER: Meal sequence: 3C1A2B4D|OTHER: Meal sequence: 2A3D4C1B|OTHER: Meal sequence: 2D4B3A1C|OTHER: Meal sequence: 3B2C1D4A|OTHER: Meal sequence: 4C2B1A3D|OTHER: Meal sequence:1B4D3C2A|OTHER: Meal sequence:4A1C2D3B|OTHER: Meal sequence:1D3A4B2C|OTHER: Meal sequence: 4D3B2C1A|OTHER: Meal sequence: 3A4C1B2D|OTHER: Meal sequence: 1C2A3D4B|OTHER: Meal sequence: 2B1D4A3C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study of Cetuximab in Combination With Gefitinib in Patients With Advanced/Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Cetuximab + Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ivabradine on Cardiovascular Events in Patients With Moderate to Severe Chronic Heart Failure and Left Ventricular Systolic Dysfunction. A Three-year International Multicentre Study
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-VEGF Therapy for Subfoveal Hemorrhage in Patients With Neovascular Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Submacular Hemorrhage|Wet Macular Degeneration|Neovascular Age-related Macular Degeneration
Interventions: DRUG: Anti-VEGF|OTHER: Hemorrhage displacement + Anti-VEGF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development and Validation Phase of Diffusion Tensor Imaging and Arterial Spin Labelling at 3 Tesla Using a Long-term Effort Model Applicable to Skeletal Muscle Characterization.
Status: COMPLETED
Conditions: Marathoners
Interventions: DEVICE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Body Composition and Fatty Liver Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Fatty Liver
Interventions: DIAGNOSTIC_TEST: Non-contrast low-dose abdomen CT|DIAGNOSTIC_TEST: Fibroscan|DIAGNOSTIC_TEST: bioelectrical impedance analysis (BIA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reliability of Rehabilitative Ultrasound for the Quadriceps Muscle and Sarcopenia in Poststroke Patients
Status: UNKNOWN
Conditions: Sarcopenia|Stroke, Complication|Quadriceps Muscle Atrophy|Hemiplegia|Ultrasonography|Hand Strength
Interventions: DIAGNOSTIC_TEST: Rehabilitative Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety, Tolerability and Pharmacokinetics Study of a Single Intravenous Dose of JNJ-49122944 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-49122944, 5 milligram (mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Targets in Acute Heart Failure With Pulmonary Congestion
Status: RECRUITING
Conditions: Acute Heart Failure|Pulmonary Congestion|Hypoxemia
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of an Artificial Intelligence System Based on Raman Spectroscopy for Diagnosis of Gastric Premalignant Lesions and Early Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Dysplasia|Gastric Intestinal Metaplasia|Gastric Cancer
Interventions: DEVICE: Raman spectroscopy based device (SPECTRA IMDx)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Opaganib in Coronavirus Disease 2019 Pneumonia
Status: COMPLETED
Conditions: Coronavirus Infections
Interventions: DRUG: Opaganib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the TEmporary Spur StEnt System for the Treatment of Lesions Located in the InfraPoplitEal ARteries Using a LIMUS-base DCB
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Critical Limb Ischemia
Interventions: DEVICE: Temporary Spur Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0432 Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic Drug-drug Interaction and Safety of Telmisartan/Amlodipine and Rosuvastatin in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteer
Interventions: DRUG: Telmisartan|DRUG: Amlodipine|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Status: RECRUITING
Conditions: Diabetic Retinopathy|Retinal Vein Occlusion|Hypertension,Essential|Retinal Vascular Disorder
Interventions: DEVICE: Swept-Source (SS) OCT Angiography|DEVICE: Spectral-Domain (SD) OCT Angiography|DEVICE: Fundus Imaging|DEVICE: Axial Length Measurement Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Dapagliflozin Plus Low Dose Pioglitazone on Hospitalization Rate in Patients With HF and HFpEF
Status: UNKNOWN
Conditions: Risk Reduction
Interventions: DRUG: Pioglitazone Plus dapaglifliozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Eltrombopag and the Bcl-extra-large (xL) Pathway in Idiopathic Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Eltrombopag|DRUG: Romiplostim|OTHER: healthy controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women
Status: COMPLETED
Conditions: Liver Cirrhosis, Biliary
Interventions: BEHAVIORAL: Psychoeducational Intervention|BEHAVIORAL: Hypnosis intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Study to Assess the Safety and Efficacy of Intravitreal ONL1204 Ophthalmic Solution in Subjects With Mac-off Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment - Macula Off
Interventions: DRUG: ONL1204 Ophthalmic Solution|DRUG: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Curcuma Domestica Extracts and Ibuprofen in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Curcuma domestica extracts|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Opioids on Circulating Tumor Cells in Radical Cystectomy
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: PROCEDURE: general anesthesia|PROCEDURE: general anesthesia combined with epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NORDIC ICD (Cardioverter Defibrillator Implantation) Trial
Status: COMPLETED
Conditions: Ventricular Tachyarrhythmia
Interventions: DEVICE: ICD implantation w/o DF test|DEVICE: ICD implantation with DF test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept of Pediatric and Adolescent EXPLORER V2 Exoskeleton in Children With Neurological and Neuromuscular Disease
Status: COMPLETED
Conditions: Cerebral Palsy|Acquired Brain Injury|Neuromuscular Diseases in Children
Interventions: DEVICE: EXPLORER V2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium Given With a Fixed Dose of Docetaxel and Prednisone in Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Elesclomol Sodium|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Triamcinolone for Clinically Significant Diabetic Macular Oedema That Persists After Laser Treatment (TDMO)
Status: COMPLETED
Conditions: Diabetic Macular Oedema
Interventions: DRUG: Triamcinolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Effects of Bilateral STN Versus GPi DBS in Parkinson's Disease Patients With MCI
Status: TERMINATED
Conditions: Parkinson's Disease|Mild Cognitive Impairment|Dementia
Interventions: DEVICE: Bilateral GPi DBS|DEVICE: Bilateral STN DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Simulation-Supported Pediatric CPR Training Based On CRM On Knowledge, Attitude, And Performance
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation
Interventions: OTHER: Pediatric Cardiopulmonary Resuscitation Training Based On Team Resource Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Rollover Study of BMS-354825 in Patients With CML and Ph+ALL
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia|Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Change in HIV Therapy on Liver Steatosis, Inflammation, and Fibrosis
Status: WITHDRAWN
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety and Evaluation of the Potential Efficacy of Autologous Platelet-rich Plasma in the Treatment of Vascular Venous Ulcers
Status: COMPLETED
Conditions: Chronic Ulcer
Interventions: DRUG: Platelet Rich Plasma|DEVICE: Osakidetza protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Fixation of Hip Fractures Using Intraoperative Simultaneous Two Axis View
Status: UNKNOWN
Conditions: Fracture Neck of Femur
Interventions: RADIATION: Imaging with two X-ray image intensifiers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Taurolock Hep 500 Versus Unfractionated Heparin as Anti-inflammatory in Hemodialysis Catheters.
Status: UNKNOWN
Conditions: Hemodialysis Catheter Infection|Thrombosis; Dialysis Catheter
Interventions: DRUG: Taurolidine heparin|DRUG: Heparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remote Motivational Interviewing to Improve Self-care in Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure
Interventions: BEHAVIORAL: Motivational interviewing performed remotely through videocalls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LBH589 Oral in Combination With Carboplatin and Paclitaxel in Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Panobinostat (LBH589), Carboplatin and Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Innovative Approach for Uniblocker Intubation
Status: UNKNOWN
Conditions: Therapeutic Procedural Complication
Interventions: OTHER: The measured distance|OTHER: formula|DEVICE: Fiberoptic bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER