pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Endovascular Catheter Cooling Combined With Cold Saline for the Treatment of Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Myocardial Reperfusion Injury|Anterior Wall Myocardial Infarction|Inferior Wall Myocardial Infarction
Interventions: PROCEDURE: Cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incisional Hernia Rate After Single-incision Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Single-incision Laparoscopic cholecystectomy|PROCEDURE: Laparoscopic Cholecystectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fourth-generation Immucillin Derivative DI4G Associated Therapy in Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis|Leishmaniasis, Cutaneous|Leishmaniasis; American
Interventions: DRUG: Immucillin DI4G|DRUG: Meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Single-blind Clinical Study to Assess Vaccine Interchangeability Between RV5 and RV1 Using Seven Combined Anti-rotavirus Prevention Programs
Status: COMPLETED
Conditions: Rotavirus Vaccine
Interventions: BIOLOGICAL: Rotarix|BIOLOGICAL: RotaTeq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of GEn1E-1124
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gen1E-1124|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding, Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: ensovibep|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SmartTarget THERAPY
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: SmartTarget Therapy|DEVICE: MRI|DEVICE: high intensity focused ultrasound (HIFU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
Status: RECRUITING
Conditions: Urologic Cancer|Urologic Neoplasms|Bladder Cancer|Prostate Cancer|Testicular Cancer|Kidney Cancer|Urethral Cancer|Penile Cancer
Interventions: DEVICE: Electromagnetic Guided Laparoscopy|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radical Retropubic Prostatectomy Versus Conventional External Beam Radiotherapy for Clinically Localized Prostate Cancer
Status: SUSPENDED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Radical retropubic prostatectomy|RADIATION: External beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis|Symptomatic Aortic Stenosis|Severe Aortic Valve Stenosis|Aortic Valve Calcification
Interventions: DEVICE: DurAVRTM THV System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety Study of 2 Different Concentrations of CD1579 Gels Versus Vehicle in the Treatment of Acne Vulgaris.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CD1579 2.5%|DRUG: CD1579 5%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
Status: COMPLETED
Conditions: Intradialytic Hypotension|Cardiac Event|Renal Insufficiency|Hospital Length of Stay
Interventions: DEVICE: Bioelectrical Impedance Analysis|PROCEDURE: Physician-guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antimicrobial Photodynamic Therapy With Erythrosine and Blue Light on Dental Biofilm Bacteria
Status: NOT_YET_RECRUITING
Conditions: Dental Plaque
Interventions: PROCEDURE: Conventional Treatment|PROCEDURE: Antimicrobial Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults
Status: COMPLETED
Conditions: Sarcopenia|Aging|Immune Function
Interventions: BIOLOGICAL: TDAP|OTHER: Acute Resistance Exercise|OTHER: Resistance Exercise Training|OTHER: Post-training Follow-up|DIETARY_SUPPLEMENT: Nutritional Supplement (Muscle Armor)|DIETARY_SUPPLEMENT: Placebo (Kool-Aid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Antihypertensive Agents Over Sleep Apnea
Status: COMPLETED
Conditions: Hypertension|Obstructive Sleep Apnea
Interventions: DRUG: Diuretics|DRUG: Calcium Channel Blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture-like Transcutaneous Electrical Nerve Stimulation on Bowel Symptom and Quality of Life in Patients With Irritable Bowel Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Acupuncture-like Transcutaneous Electrical Nerve Stimulation|Irritable Bowel Syndrome
Interventions: DEVICE: acupuncture-like transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Pharmacological and Psychological Intervention for Late Prodromal States of Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Psychoses
Interventions: BEHAVIORAL: Supportive management|DRUG: Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: ETC-1002|DRUG: Placebo|DRUG: Statin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum-derived Bovine Immunoglobulin Effect on Mucositis
Status: TERMINATED
Conditions: Mucositis
Interventions: DIETARY_SUPPLEMENT: SBI|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SELUTION4SFA Trial
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Superficial Femoral Artery Stenosis
Interventions: DEVICE: SELUTION SLR™ 018 DEB|DEVICE: Plain (Uncoated) Balloon Angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trans-nasal Endoscopy for Bariatric Patients
Status: NOT_YET_RECRUITING
Conditions: Obesity|Obesity, Morbid|Obese|GI Disorders|Gastrointestinal Diseases
Interventions: DEVICE: Transnasal Endoscopy|PROCEDURE: Esophagogastroduodenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Dietary Education and Education on Phosphate Binder Use in Hemodialysis Patients
Status: COMPLETED
Conditions: Hyperphosphatemia|End-stage Renal Disease
Interventions: BEHAVIORAL: Dietary education|BEHAVIORAL: Education on phosphate binder use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Maximum Tolerated Dose of Axitinib in Combination With Radiotherapy for HCC
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Axitinib|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Radiotherapy Using MR-linac for Pancreatic Neuroendocrine Tumours in MEN1 Patients
Status: RECRUITING
Conditions: Neuroendocrine Tumor of Pancreas|Multiple Endocrine Neoplasia Type 1
Interventions: RADIATION: High-dose-high precision MR-guided radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motorized Movement Therapy & Pulmonary Functions in Down Syndrome
Status: COMPLETED
Conditions: Pulmonary Functions|Down Syndrome
Interventions: OTHER: motorized movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LOW LOAD RESISTANCE BLOOD FLOW RESTRICTION TRAINING VERSUS NEUROMUSCULAR TRAINING IN KNEE OSTEOARTHRITIS
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: OTHER: Traditional exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17
Status: NOT_YET_RECRUITING
Conditions: Hypogonadism, Male
Interventions: DRUG: Relugolix 120Mg Tab|DIETARY_SUPPLEMENT: Curcumin|DRUG: Testosterone Undecanoate 237 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Study the Use of Humanized CD25 in Preventing the Relapse of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Daclizumab|DEVICE: NB-UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesity Prevention After Smoking Cessation in Menopause
Status: COMPLETED
Conditions: Obesity|Menopause
Interventions: BEHAVIORAL: Individualized dietary-control and exercise program|BEHAVIORAL: Weight-management and smoking cessation maintenance|BEHAVIORAL: Smoking Cessation program
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: EndovaScular Versus mediCaL mAnagement of Uncomplicated Type B Intramural heMatoma Trial (ESCLAIM)
Status: UNKNOWN
Conditions: Intramural Hematoma
Interventions: PROCEDURE: Thoracic endovascular aortic repair plus optimal medical therapy|DRUG: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With Lenvatinib and PD-1 Inhibitor in Infiltrative Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Lenvatinib|PD-1 Inhibitor|Hepatic Arterial Infusion Chemotherapy
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Tislelizumab|DRUG: Toripalimab|DRUG: Sintilimab|DRUG: Camrelizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulmonary REsistance Modification Under Treatment With Sacubitril/valsartaN in paTients With Heart Failure With Reduced Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Sacubitril-valsartan|DRUG: Enalapril|DRUG: placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Infusion of Campath-1H Followed by Subcutaneous Injections in Previously Treated Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Campath-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell Lymphoma
Status: WITHDRAWN
Conditions: Anaplastic Large Cell Lymphoma, ALK-Positive|CD30-Positive Neoplastic Cells Present|Systemic Anaplastic Large Cell Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Ceritinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Effect of Food Supplement in People Infected With Coronavirus
Status: COMPLETED
Conditions: COVID-19 Virus Infection
Interventions: DIETARY_SUPPLEMENT: LCLT : 68% elemental L-carnitine and 32 % Tartric acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Vulvar Intraepithelial Neoplasia (VIN)
Interventions: DEVICE: Sonopet Ultrasonic Aspirator|DEVICE: CO2 Laser Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transnasal Cooling for Migraine
Status: TERMINATED
Conditions: Migraine|Episodic Migraine|Migraine With Aura|Migraine Without Aura
Interventions: DEVICE: CoolStat active device|DEVICE: CoolStat sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney Function
Status: COMPLETED
Conditions: Distal Urethral Cancer|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: DRUG: Gemcitabine hydrochloride|DRUG: Paclitaxel|DRUG: Doxorubicin hydrochloride|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Assessing the Efficacy and Safety ParActin® in Individuals With Upper Respiratory Tract Infections
Status: RECRUITING
Conditions: Upper Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: ParActin®: 300 mg + MCC: 100 mg (± 10%) per Capsule|DIETARY_SUPPLEMENT: MCC: 400 mg (± 10%) per Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure Chamber
Status: COMPLETED
Conditions: Allergic Asthma|Allergic Rhinitis
Interventions: DEVICE: KOLMI® surgical face mask (OP-Air)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety & Efficacy Study of the Adiana System for Women Who Desire Permanent Birth Control (Sterilization)
Status: TERMINATED
Conditions: Reproductive Sterilization
Interventions: DEVICE: Adiana Transcervical Sterilization System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Passive Exercise on Systemic Endothelial Function in Elderly Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Endothelium-derived Factors|Elderly
Interventions: OTHER: Passive leg cycle exercise with stretching and resistance training|OTHER: Stretching and resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reliability of Light Induced Fluorescence Intraoral Camera Versus Visual-Tactile Method in Assessment of Marginal Integrity of Resin Composite Restorations: Diagnostic Invivo Study
Status: UNKNOWN
Conditions: Microleakage Around Resin Composite Restorations
Interventions: DIAGNOSTIC_TEST: Light induced fluorescence intraoral camera|DIAGNOSTIC_TEST: Visual-tactile assessment method according to FDI criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: First-in-man Trial of the Magnetic-controlled Balloon Inflation Mechanism of a Novel Ingestible Weightloss Microcapsule
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: Prototype Microcapsule Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Dutch Version Fear-Avoidance Component Scale (FACS)
Status: COMPLETED
Conditions: Musculoskeletal Pain|Musculoskeletal Pain Disorder|Fear of Pain|Fear of Injury|Low Back Pain, Recurrent|Neck Pain|Shoulder Pain|Knee Pain Chronic|Hip Pain Chronic|PROMs
Interventions: DIAGNOSTIC_TEST: Assessment of disability and behavior (by questionnaires)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain Syndrome
Interventions: OTHER: Education and training|BEHAVIORAL: Pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels
Status: RECRUITING
Conditions: Congenital Sucrase-Isomaltase Deficiency|CSID|Sucrase Isomaltase Deficiency
Interventions: BIOLOGICAL: Sucraid (sacrosidase) Oral Solution 8500 IU/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celution Prepared Adipose Derived Regenerative Cells in the Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Celution Device|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization Before Radical Prostatectomy in Prostate Cancer: A Proof-of-concept Study
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Prostatic Artery Embolization (PAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of LCP-Tacro(TM) Once Daily And Prograf® Twice A Day in Adult De Novo Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Failure|Renal Failure
Interventions: DRUG: Tacrolimus (Tacro™)|DRUG: Prograf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Analysis of Introperative RegenLab PRP and Hyaluronic Acid in Patients With Knee ACL Tear
Status: UNKNOWN
Conditions: PRP|ACL|Hyaluronic Acid
Interventions: COMBINATION_PRODUCT: RegenLab PRP|COMBINATION_PRODUCT: hyaluronic acid|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Scleroderma Patient-centered Intervention Network (SPIN) Support Group Leader Education Program Feasibility Trial
Status: COMPLETED
Conditions: Scleroderma|Systemic Sclerosis
Interventions: OTHER: SPIN-SSLED Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulsta® Transcatheter Pulmonary Valve Korean Multicenter Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Heart Defect|Pulmonary Valve; Insufficiency, Congenital|Pulmonary Valve Stenosis
Interventions: DEVICE: Pulsta® Transcatheter Pulmonary Valve (TPV) Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ibandronate in Diabetic Patients
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal|Type 2 Diabetes
Interventions: DRUG: Ibandronate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premenopausal Patient With Hormone Responsive, HER2 Negative, Lymph Node Positive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Adriamycin+Cyclophosphamide>Docetaxel|DRUG: GnRHa with Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetylcholine Receptors From Human Muscles as Pharmacological Target for ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: endocannabinoid palmitoylethanolamide (PEA)|DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A New Securement Method for External Tunneled Central Venous Access Devices (CVAD)
Status: RECRUITING
Conditions: Central Venous Catheter Exit Site Infection|Central Venous Catheter Related Bloodstream Infection
Interventions: DEVICE: Central venous access device (CVAD) Snuggie Securement Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Values Interventions for Increasing Engagement With What is Feared in Individuals With Specific Phobias
Status: COMPLETED
Conditions: Specific Phobia
Interventions: BEHAVIORAL: Personal Values Intervention|BEHAVIORAL: Prosocial Values Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm|Coronary Heart Disease NOS|Unheralded Coronary Death|Intracerebral Haemorrhage|Heart Failure|Ischemic Stroke|Myocardial Infarction|Stroke|Peripheral Arterial Disease|Stable Angina Pectoris|Subarachnoid Haemorrhage|Transient Ischemic Attack|Unstable Angina|Cardiac Arrest, Sudden Cardiac Death
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study for Postoperative Chemoradiation Using Triweekly Cisplatin in Cervical Cancer Patients
Status: WITHDRAWN
Conditions: Cervical Neoplasms
Interventions: RADIATION: tri-weekly cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload
Status: TERMINATED
Conditions: Heart Failure
Interventions: COMBINATION_PRODUCT: sc2Wear Furosemide Infusor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Use Biosensing Devices to Monitor PA and Resp. Function in Smokers w and w/o Resp. Symptoms/COPD
Status: COMPLETED
Conditions: Signs and Symptoms, Respiratory|Mobile Applications|Activity Trackers|Respiratory Function Tests
Interventions: DEVICE: Anamed OEM device; Air Next mobile spirometry device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Strategy to Encourage Early Removal of Central Venous Catheters
Status: WITHDRAWN
Conditions: Vascular Access Complication|Central Line Complication|Central Line-Associated Infection|Superficial Vein Thrombosis|Deep Vein Thrombosis
Interventions: DEVICE: Midline catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open Label, Single Centre Mass Balance C14 Study in Patients With Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: AZD1152|DRUG: C14 AZD1152
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Study of Umeclidinium (UMEC) Bromide Versus Placebo in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: UMEC|DRUG: Fluticasone Furoate|DRUG: Albuterol/salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Acceptance and Commitment Therapy for HIV-infected At-risk Drinkers
Status: COMPLETED
Conditions: Treatment
Interventions: BEHAVIORAL: Brief Acceptance and Commitment Therapy|BEHAVIORAL: Brief Alcohol Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hirudin Plus Aspirin in the Secondary Prevention of Cardioembolic Stroke Due to Nonvalvular Atrial Fibrillation
Status: COMPLETED
Conditions: Cardioembolic Stroke|Atrial Fibrillation
Interventions: DRUG: hirudin plus aspirin|DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: temozolomide|DRUG: thalidomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From "Real World"
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate(necessary)|BIOLOGICAL: infliximab|BIOLOGICAL: etanercept|BIOLOGICAL: adalimumab|DRUG: leflunomide (permitted, not necessary)|DRUG: NSAIDs (permitted,not necessary)|DRUG: Glucocorticoids (permitted,not necessary)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Grade I Neuroendocrine Carcinoma|Grade II Neuroendocrine Carcinoma|Grade III Neuroendocrine Carcinoma|Metastatic Neuroendocrine Carcinoma|Neuroendocrine Carcinoma|Recurrent Small Cell Lung Carcinoma|Refractory Small Cell Lung Carcinoma|Lung Cancer Stage IV|Large Cell Neuroendocrine Carcinoma|Neuroendocrine Tumors|Small Cell Lung Cancer Metastatic|Small-cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Edoxaban in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With Aspirin and Clopidogrel
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Edoxaban 60 mg|DRUG: Edoxaban 30 mg|DRUG: Clopidogrel 75 mg|DRUG: Aspirin 81 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of INC280 Alone, and in Combination With Erlotinib, Compared to Chemotherapy, in Advanced/Metastatic Non-small Cell Lung Cancer Patients With EGFR Mutation and cMET Amplification
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: INC280 single agent|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlactatemia|Cardiac Disease|Bypass Complication|Valve Disease, Heart|Vitamin C
Interventions: DIETARY_SUPPLEMENT: ascorbic acid,|OTHER: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia
Status: RECRUITING
Conditions: Pediatric Tumor|Familial Cancer|Solid Tumor, Childhood|Hematological Tumor
Interventions: GENETIC: Exome sequencing in pediatrics cancers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: Standard long-lasting insecticidal net|OTHER: Chlorfenapyr insecticide treated net|OTHER: Indoor residual spraying
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Symptomatic Cerebral Cavernous Malformation Trial of REC-994
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Cavernous Malformation
Interventions: DRUG: REC-994|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mobile-Bearing and Fixed-Bearing All-Polyethylene Tibia Total Knee Designs
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: TKA surgery with the rotating platform mobile-bearing knee design|PROCEDURE: TKA surgery with the all-polyethylene tibia knee design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biweekly Gemcitabine and Docetaxel as First Line Therapy for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gemcitabine and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Physician Empathy, Compassionate Care and Wellness
Status: COMPLETED
Conditions: Burnout, Professional|Resilience|Stress, Emotional
Interventions: BEHAVIORAL: Mayo Clinic SMART program (Stress Management and Resilience Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
Status: RECRUITING
Conditions: Migraine|Menstrual Migraine|Menstrually Related Migraine
Interventions: DRUG: Fremanezumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Loncastuximab Tesirine Versus Idelalisib in Participants With Relapsed or Refractory Follicular Lymphoma
Status: TERMINATED
Conditions: Relapsed Follicular Lymphoma|Refractory Follicular Lymphoma
Interventions: DRUG: Loncastuximab Tesirine|DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of [18F]PSMA-1007 PET/CT in Patients With Biochemial Recurrent Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Prostate Cancer Recurrent
Interventions: DRUG: [18F]PSMA-1007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Single Ascending Dose (SAD)|DRUG: Multiple Ascending Dose (MAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Trial to Prove Equal Blood Concentrations of Two Different Fluconazole Formulations
Status: COMPLETED
Conditions: Pharmacology, Clinical
Interventions: DRUG: Fluconazole (BAYT006267) 150 mg capsules|DRUG: Fluconazole 150 mg capsules (DiflucanTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Nitazoxanide 600 mg BID Versus Placebo for the Treatment of Hospitalized Patients With COVID-19
Status: RECRUITING
Conditions: covid19
Interventions: DRUG: Nitazoxanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Administration of PCSK9 Inhibitor to Acute Ischemic Stroke Patients Associated With Atherosclerosis on the Stroke Prognosis and Lipid Profile
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute Ischemic|PCSK9 Inhibitor
Interventions: DRUG: Alirocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.
Status: COMPLETED
Conditions: Roux-en-y Gastric Bypass|Post Prandial Hypoglycemia
Interventions: COMBINATION_PRODUCT: Administration of glucose and controlled induction of hypoglycaemia.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Dalfampridine on Upper Extremity Function in Patients With MS
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Sustained-release oral dalfampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Procore Needle® for Diagnosis of Lung Cancer
Status: COMPLETED
Conditions: Endobronchial Transbronchial Needle Aspiration Lung Cancer Procore
Interventions: PROCEDURE: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
Status: COMPLETED
Conditions: Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Interventions: DRUG: XOPH5 Ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring and Treatment of Relapsed Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation in Children
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Bortezomib|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-energy Linear Extracorporal Shock Wave Therapy for Erectile Dysfunction.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DEVICE: Sham treatment|DEVICE: ESWT treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma
Status: NOT_YET_RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunological and Regenerative Implications of Corrosion of Dental Materials
Status: COMPLETED
Conditions: Caries; Enamel|Gingivitis
Interventions: COMBINATION_PRODUCT: Exposure to oral antiseptics or enamel remineralisation agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bleach vs. Bubbles: Assessing the Impact of the Bathroom Environment on Eczema
Status: COMPLETED
Conditions: Eczema|Atopic Dermatitis|Atopic Dermatitis and Related Conditions
Interventions: OTHER: Bubbles|OTHER: Bleach and Bubbles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy, Immunogenicity and Safety of the Sputnik-Light
Status: UNKNOWN
Conditions: COVID-19 Prevention
Interventions: BIOLOGICAL: Sputnik Light|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Secretin-Stimulated Magnetic Resonance Cholangiopancreatography (S-MRCP) in Pancreatic Patients
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Synthetic Human Secretin|PROCEDURE: Secretin-Enhanced Magnetic Resonance Cholangiopancreatography|PROCEDURE: Secretin-Enhanced Endoscopic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CNTO 136 (Sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Anti-TNF-Alpha Therapy (SIRROUND-T)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: Sirukumab|DRUG: Sirukumab|DRUG: Sirukumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of HDR With EBRT in Localised Prostate Cancer,Toxicity and Quality of Life Assessment
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: HDR Brachytherapy|RADIATION: External beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Use of RenalGuard to Protect Patients at High Risk of AKI
Status: UNKNOWN
Conditions: Cardiovascular Disease|Acute Kidney Injury
Interventions: DEVICE: RenalGuard|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Comparative Study of Refractive Outcome of STAAR and Alcon Toric Intraocular Lenses
Status: COMPLETED
Conditions: Astigamtism
Interventions: PROCEDURE: Phacoemulsification with implantation of toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: High-Field MRI Characterization of Wrist and Hand Cartilage Abnormalities in Inflammatory and Chronic Rheumatisms
Status: COMPLETED
Conditions: Abnormality|Inflammation|Rheumatism
Interventions: OTHER: high-field MRI (3 Teslas)|OTHER: high-field MRI (3 Teslas)|OTHER: high-field MRI (3 Teslas)|OTHER: high-field MRI (3 Teslas)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|SLE (Systemic Lupus)|Autoimmune
Interventions: DRUG: CUG252|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Nausea and Vomiting of Pregnancy
Status: COMPLETED
Conditions: Hyperemesis Gravidarum|Nausea|Vomiting|Pregnancy
Interventions: PROCEDURE: Day care|PROCEDURE: Inpatient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine Spray for Pain Relief During Endometrial Biopsy: a Randomized, Double-blind, Placebo-controlled Clinical Trial
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 2 Dose Regimens of TEV-48125 Versus Placebo for the Preventive Treatment of Episodic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Prophylactic Use of Antibiotics Within 72 Hours After Acute Burn Injury in Patients
Status: NOT_YET_RECRUITING
Conditions: Burn Infection
Interventions: DRUG: not using antibiotic|DRUG: using antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: DRUG: Cerebrolysin®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation Defects
Status: COMPLETED
Conditions: Furcation Defects
Interventions: PROCEDURE: Open flap debridement (OFD)|PROCEDURE: OFD with Platelet rich fibrin (PRF)|PROCEDURE: OFD with Platelet rich fibrin (PRF)+1% Alendronate (Drug) in gel form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum
Status: COMPLETED
Conditions: Spondylosis|Spondylolisthesis|Neurogenic Claudication|Foraminal Stenosis
Interventions: OTHER: Chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Drug-Drug Interaction Study Between AZD1981 and Pravastatin to Study the Effect of AZD1981 on the Kinetics of Pravastatin
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: AZD1981|DRUG: AZD1981|DRUG: pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 2-Part Trial in Subjects With Type 2 Diabetes and in Healthy Subjects to Evaluate GSK1614235, a New Glucose Lowering Drug to Treat Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK1614235|DRUG: Sitagliptin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation of TKI With or Without Chemotherapy Beyond Gradual Progression
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: EGFR tyrosine kinase inhibitor|DRUG: EGFR tyrosine kinase inhibitor with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing
Status: COMPLETED
Conditions: Presymptomatic Huntington Disease
Interventions: BEHAVIORAL: psychological interview|RADIATION: MRI|OTHER: cognitive tests|OTHER: neurological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial Investigating the BeGraft Peripheral Plus Stent Graft System for Iliac Lesion Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: BeGraft Peripheral Plus Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microdose Study of Melphalan, Bortezomib and Dexamethasone
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE