pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Amount of Cementum After Scaling, Root Planing and Glycine Air Polishing
Status: COMPLETED
Conditions: Dental Diseases
Interventions: DEVICE: Air Flow Master Piezon®, EMS SA, Nyon, Swiss|DEVICE: Gracey curettes, American Eagle, Missoula, MT, USA|DEVICE: Air-flow® Powder Perio, EMS SA, Nyon, Swiss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Advanced B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large Cell Lymphoma|Burkitt's Lymphoma|High Grade B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: IT Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Virtual Reality on Upper Extremity Function in Hemiplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Virtual Reality Exercises using Hand Tutor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patella Fracture : A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Patella Fracture|Aging
Interventions: PROCEDURE: Group A: Surgical Treatment|OTHER: Group B: Conservative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Captain Sonar Impact on Trauma Patient Management
Status: COMPLETED
Conditions: Trauma Injury
Interventions: BEHAVIORAL: Captain Sonar Exposition|BEHAVIORAL: Monopoly Exposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans
Status: COMPLETED
Conditions: Binge Drinking|Alcohol Abuse|Alcohol Dependence|HIV Infections
Interventions: BEHAVIORAL: HIV support group|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Computer-based Intervention to Augment Home Visitation Services: The E-Parenting Project
Status: COMPLETED
Conditions: Child Maltreatment
Interventions: BEHAVIORAL: Computer Assisted Healthy Families America Home Visitation|BEHAVIORAL: Healthy Families America Home Visitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single Center Trial of Donor Site Wound Dressings After Split Thickness Skin Grafting.
Status: COMPLETED
Conditions: Donor Site Complication|Skin Graft Scar
Interventions: BIOLOGICAL: different types of dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: TAF Switch in F3/4 CHB pt With Partial Response to NUC (ESTAB-AFPVR)
Status: UNKNOWN
Conditions: Hepatitis B|Fibrosis and Cirrhosis of Liver
Interventions: DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for COVID-19 and Monitoring of Serological Responses to SARS-CoV-2 in Healthcare Workers
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2
Interventions: DIAGNOSTIC_TEST: Nasal swab|DIAGNOSTIC_TEST: Serum testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Pioglitazone Hydrochloride When Given Together to Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: pioglitazone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms
Status: COMPLETED
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Magnetic Resonance Enterography for Predicting Peritoneal Cancer Index
Status: UNKNOWN
Conditions: Hyperthermic Intraperitoneal Chemotherapy|Cytoreductive Surgery|Peritoneal Carcinomatosis
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Occlusion and Disocclusion Time in Immediately Loaded Overdentures Supported by Two Splinted Versus Non Splinted Interforaminal Implants
Status: NOT_YET_RECRUITING
Conditions: Edentulous Jaw
Interventions: PROCEDURE: solitary Implant loading with ball attachment|PROCEDURE: splinted Implant loading with intra oral welding|PROCEDURE: complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Antagonistic Effect of Plant Nutrients on Health Damage Caused by Environmental Pollutants
Status: NOT_YET_RECRUITING
Conditions: Intestinal Functional Disorder|Inflammation
Interventions: DIETARY_SUPPLEMENT: Compound plant nutrients|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: REal World Data in LYmphoma and Survival in Adults
Status: RECRUITING
Conditions: Diffuse Large B Lymphoma (DLBCL)|Follicular Lymphoma (FL)|Mantle Cell Lymphoma (MCL)|Marginal Zone Lymphoma (MZL)|T-cell Lymphoma (T-NHL)|Hodgkin's Lymphoma (HL)|Burkitt Lymphoma (BL))
Interventions: OTHER: Real-life epidemiological platform of lymphoma in France
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Oral Administration of the Phage Cocktail, VRELysin™, In Healthy and VRE-Colonized Subjects
Status: RECRUITING
Conditions: Vancomycin-Resistant Enterococcal Colonization
Interventions: BIOLOGICAL: VRELysin™|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study Comparing 99mTc-EC-DG SPECT/CT With 18F FDG PET/CT in Patients With Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: Radiolabeled (99Tc) EC-DG (ethylenedicysteine-deoxyglucose)|RADIATION: 18 F fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Diabetes Patient Education and Self-Management Education in Persons With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Regular diabetes patient education|BEHAVIORAL: Augmented diabetes patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement
Status: WITHDRAWN
Conditions: Bardet-Biedl Syndrome|Visual Impairment
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)
Status: NOT_YET_RECRUITING
Conditions: Irritable Bowel Syndrome|Lactose Intolerance|Lactose Malabsorption
Interventions: DRUG: alverine-citrate + simethicone and lactase|DRUG: alverin-citrate + simethicone with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Aged 3 Through 5 Years Who Have a Specified CFTR Gating Mutation
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: ivacaftor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Participation in a Prostate Cancer Risk Assessment Program
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Cognitive Affective preparation|BEHAVIORAL: General Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Preoperative Therapy for Gastric and Esophagogastric Junction Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Epirubicin + cisplatin + 5-fluorouracil OR epirubicin + cisplatin + capecitabine OR epirubicin + oxaliplatin + capecitabine OR 5-Fluorouracil + leucovorin + oxaliplatin + docetaxel|RADIATION: Preoperative chemoradiotherapy|PROCEDURE: Gastric resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuronal Mechanisms of Human Episodic Memory
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy Intractable
Interventions: BEHAVIORAL: Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot and Descriptive Study of the Effects of Setting up Computer-assisted Music (CAM) Remediation Groups on the Cognitive Functioning of Young Patients With a First Episode Psychosis (PEP)
Status: RECRUITING
Conditions: Psychotic Episode
Interventions: OTHER: Computer-assisted Music remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Parent Involvement in the Treatment of Adolescent Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Dysthymic Disorder|Depressive Disorder NOS|Adjustment Disorder
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Depressed Adolescents|BEHAVIORAL: Interpersonal Psychotherapy for Depressed Adolescents and Parents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Explore the Efficacy and Safety of edoxabaN in Patients After Heart Valve Repair or Bioprosthetic vaLve Replacement (ENAVLE Trial)
Status: COMPLETED
Conditions: MV(Mitral Valve) Repair
Interventions: DRUG: Edoxaban|DRUG: Warfarin|DRUG: parenteral anti-coagulant (UFH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical and Psychosocial Stress on Functional Hypothalamic Amenorrhea in Exercising Women
Status: RECRUITING
Conditions: Amenorrhea Secondary
Interventions: BEHAVIORAL: Exercise Stress|BEHAVIORAL: Psychosocial Stress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Sangustop® as Haemostatic Agent Versus a Carrier-Bound Fibrin Sealant During Liver Resection
Status: COMPLETED
Conditions: Hemostasis|Liver Surgery
Interventions: DEVICE: Sangustop|DRUG: Tachosil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-Level Monochromatic Red-Light for High Myopia Control in Adults
Status: NOT_YET_RECRUITING
Conditions: High Myopia
Interventions: DEVICE: Myopic amblyopia comprehensive treatment instrument|DEVICE: Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54175446 150 mg|DRUG: JNJ-54175446 600 mg|DRUG: Midazolam 2 mg|DRUG: Warfarin 10 mg|DRUG: Caffeine 50 mg|DRUG: Dextromethorphan 30 mg|DRUG: Bupropion 150 mg|DRUG: Omeprazole 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Thymosin α-1 on the Efficacy of Concurrent Chemoradiotherapy Followed by Immunotherpay Consolidation for Locally Advanced NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: definitive radiotherapy|DRUG: induction chemo-immunotherapy|DRUG: concurrent chemotherapy|DRUG: Immunotheapy consolidation|DRUG: Thymosin Alpha1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Performance in Drivers With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Goal Management Training|BEHAVIORAL: Processing Speed Training|BEHAVIORAL: Brain Health Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Complementary Intracoronary Streptokinase Administration Immediately After Primary Percutaneous Coronary Intervention on Microvascular Perfusion and Late Term Infarct Size in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: intracoronary infusion,|PROCEDURE: primary percutaneous coronary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Busulfan-fludarabine Conditioning and T-cell Depleted Allogeneic Stem Cell Transplantation for Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myeloma
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Campath|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efﬁcacy and Safety of Weight-Based Insulin Titration Regimen in Hospitalized Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Efficacy, Self|Adverse Effect
Interventions: OTHER: Weight-based|OTHER: Glucose level-based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NDMM Patients Candidates for ASCT Comparing Extended VRD Plus vs. Isa-VRD vs. Isa-V-Iberdomide
Status: NOT_YET_RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Isatuximab|DRUG: Iberdomide|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BBI608 in Combination With Sorafenib, or BBI503 in Combination With Sorafenib in Adult Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: BBI608|DRUG: BBI503|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Therapeutic Techniques for the Treatment of Acromioclavicular Dislocations
Status: WITHDRAWN
Conditions: Acromioclavicular Joint Dislocation
Interventions: PROCEDURE: open reduction internal fixation|OTHER: sling rest and early functional recovery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Cancer
Interventions: DRUG: Stereotactic Body Radiation Therapy (SBRT)|DEVICE: Stereotactic Linear Accelerator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed
Status: ACTIVE_NOT_RECRUITING
Conditions: Whooping Cough|Diphtheria|Tetanus
Interventions: BIOLOGICAL: Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed|BIOLOGICAL: Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine, Adsorbed|BIOLOGICAL: Diphtheria,tetanus,pertussis(acellular,component),poliomyelitis(inactivated) vaccine(absorbed) and Haemophilus influenzae type b conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pre and Postoperative Gait Analysis of Randomized Patient to 2 Different Cement Fixation Methods
Status: COMPLETED
Conditions: Gait Analysis|Hip Arthritis|Total Hip Arthroplasty
Interventions: OTHER: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Aerosolized Prostacyclin for Pulmonary Hypertension Requiring Inhaled Nitric Oxide
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Inhaled Iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity, Gait, and Efficacy (AGE II): Functional Limitations and Quality of Life
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Home-based, DVD-delivered physical activity|BEHAVIORAL: Usual care/Wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Cyclosporine|DRUG: Daclizumab|DRUG: Mycophenoate Mofetil|DRUG: Prednisolone|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Terms Effects of Medial Branch Block vs Para-spinal Muscle Injection in Patients With Non-specific CLBP
Status: UNKNOWN
Conditions: Low Back Pain, Mechanical
Interventions: OTHER: Medial branch block in one side|OTHER: paravertebral deep intramuscular (PDI) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: IFA|BIOLOGICAL: 6MHP|BIOLOGICAL: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Treatment of the Post-extraction Tooth Socket Healing in Subjects With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Delayed Wound Healing|Tooth Extraction Status Nos
Interventions: DEVICE: Hyaluronic acid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAFETY AND EFFICACY OF ENDOSCOPIC CONVENTIONAL CYANOACRYLATE GLUE VS EUS-GUIDED COIL PLUS CYANOACRYLATE TECHNIQUE IN THE TREATMENT OF GASTRIC VARICES: A RANDOMIZED CONTROLLED TRIAL
Status: UNKNOWN
Conditions: Glue; Dependence
Interventions: PROCEDURE: EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Transepithelial Corneal Collagen Cross-linking (CXL) in Treatment of Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: CXL without epithelial removal|PROCEDURE: CXL with epithelial removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Power Versus Temperature Controlled Ablation for Treatment of VT
Status: RECRUITING
Conditions: Ventricular Tachycardia
Interventions: DEVICE: Temperature controlled DiamondTemp (DT) ablation catheter|DEVICE: Tacticath/Tactiflex (TF) ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib as Neoadjuvant Treatment in Patients With Stage ⅢA N2 NSCLC With Activating EGFR Mutation.
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Magnesium on Vascular Calcification in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Vascular Calcification|Uremic Osteodystrophy
Interventions: DIETARY_SUPPLEMENT: Mablet 360 mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Metastases|Gastric Cancer
Interventions: DRUG: S-1, Oxaliplatin sintilimab HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Stability of the Anterior Cruciate Ligament (ACL) Deficient Knee
Status: SUSPENDED
Conditions: Knee Injury
Interventions: OTHER: Exercise protocol with perturbation exercises.|OTHER: Exercise protocol with traditional exercises for stability and balance.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Movement Pattern Training and Manual Therapy for Prearthritic Hip Disorders
Status: COMPLETED
Conditions: Hip-related Groin Pain|Femoroacetabular Impingement|Dysplasia Mild|Prearthritic Hip Disorder
Interventions: OTHER: Movement Pattern Training|OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Pegylated Filgrastim and Filgrastim in Support for Chemotherapy
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: pegylated filgrastim and ﬁlgrastim|DRUG: ﬁlgrastim and pegylated filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COmprehensive Remote Ischemic Conditioning in Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction, Anterior Wall
Interventions: DEVICE: comprehensive remote ischaemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Evaluation of the Beacon Aqueous Microshunt in Patients Refractory to Drug Therapy in the European Union
Status: TERMINATED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: Beacon Aqueous Microshunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Genic Expression Profiles of the Epithelium of the Nose and Bronchi in Healthy and Allergic Subjects
Status: UNKNOWN
Conditions: Allergy
Interventions: PROCEDURE: bronchofiberscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Observational Study to Assess the Effectiveness and Safety of Cemiplimab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) in Routine Clinical Practice Settings in Europe (CEMI-LUNG)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Cemiplimab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pleiotropic Effects of Azilsartan Medoxomil Over Insulin Resistance in Obese, Diabetic and Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension|Obesity|Type 2 Diabetes Mellitus
Interventions: DRUG: Azilsartan 40 mg.|DRUG: Azilsartan 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison in the Treatment of Acute Cystitis Using Cephalosporin and Norfloxacin (CECI)
Status: WITHDRAWN
Conditions: Cystitis
Interventions: DRUG: Norfloxacin|DRUG: Cephalosporins|DRUG: Cephalosporins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Glioblastoma Multiforme or Brain Stem Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty
Status: TERMINATED
Conditions: Urethral Stricture
Interventions: PROCEDURE: Ventral buccal mucosa onlay urethroplasty|PROCEDURE: Dorsal buccal mucosa onlay urethroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of ALIMTA (LY231514, Pemetrexed) Plus Oxaliplatin Administered Every 21 Days for First-Line Treatment of Patients With Advanced Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: ALIMTA|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Fenestrations in Tube Shunt Implants During the Early Postoperative Period
Status: TERMINATED
Conditions: Glaucoma
Interventions: PROCEDURE: Needle fenestration|PROCEDURE: Suture wick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy|Spine Deformity|Scoliosis
Interventions: DEVICE: ThecaFlex DRx System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Study of Bridging alloHSCT After Treatment With Obinutuzumab in Combination With Chidamide and Venetoclax in RR Ph-ALL and B-cell Lymphoma Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: chidamide|DRUG: Venetoclax Oral Tablet|DRUG: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Rivastigmine Patch in Patients With Mild to Moderate Alzheimer's Disease Switched From Cholinesterase Inhibitors
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UK Registry for Baroreflex Activation Therapy
Status: TERMINATED
Conditions: Baroreflex Failure Syndrome|Hypertension, Resistant to Conventional Therapy
Interventions: DEVICE: Baroreflex Activation Therapy with Barostim Neo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Clomiphene Citrate Administration vs. Stair-step Approach
Status: COMPLETED
Conditions: Ovulatory Dysfunction|Anovulation|Ovulation Induction
Interventions: DRUG: clomiphene citrate|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SARS-CoV-2 Variant (BA.4 /5) mRNA Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: ABO1020|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of XT-150 for Facet Joint Osteoarthritis Pain
Status: COMPLETED
Conditions: Facet Joint Pain|Back Pain|Inflammation
Interventions: BIOLOGICAL: XT-150|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Induction Anesthetic Agents on Serum Cortisol Concentration in Morbidly Obese Patients.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Intravenous administration of the induction agent of general anesthesia (etomidate or thiopental)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating NSCLC Minimal Stage IV With Curative Intent
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Induction chemotherapy and concurrent radiation|OTHER: Consolidation: Radiation therapy to metastatic sites
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced Unresectable or Metastatic Solid Tumors
Interventions: DRUG: IBI343
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Study for the Treatment of Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Duloxetine hydrochloride|DRUG: Duloxetine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validating the Novel Classification for the Assessment and Grading of Unexpected Events in Pediatric Surgery: The Clavien-Madadi Classification
Status: RECRUITING
Conditions: Complication of Surgical Procedure
Interventions: OTHER: Case Scenarios of complications to be ranked / classified according to classifications (for the severity grading of events)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial Comparing Misoprostol and Foley Bulb for Pregnancy Termination in the Second Trimester
Status: COMPLETED
Conditions: Pregnancy Trimester, Second|Induced Abortion
Interventions: DEVICE: Foley bulb|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Gastric ESD With or Without Epineprhine Added Solution
Status: COMPLETED
Conditions: Gastric Neoplasm|Early Gastric Cancer
Interventions: PROCEDURE: Endoscopic submucosal dissection|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiome Effect of Omadacycline on Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Omadacycline|DRUG: Vancomycin Pill|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autonomic Nervous System and Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Orthostatic Intolerance|Postural Tachycardia Syndrome
Interventions: OTHER: Autonomic Function Testing|OTHER: Saline infusions|DRUG: L-NMMA trimethaphan|DRUG: methyldopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Laser Used in the Treatment of Hypomineralized Occlusal Lesions in Teeth Enamel Affected by MIH
Status: COMPLETED
Conditions: Dental Enamel Hypoplasia
Interventions: PROCEDURE: Diode laser group|PROCEDURE: Glass Ionomer Sealing Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance of a Transcutaneous Bone Conduction Hearing Solution (Baha® Attract System)
Status: COMPLETED
Conditions: Deafness|Hearing Loss|Hearing Loss, Conductive
Interventions: DEVICE: Baha Attract System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK)
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Stop current treatment (anti-HBV neucleos(t)ides)|DRUG: Keep current treatment (anti-HBV neucleos(t)ides)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between the Change of Peripheral Lymphocyte Subsets and Clinically Amyopathic Dermatomyositis Combined With Rapidly Progressive Interstitial Lung Disease
Status: UNKNOWN
Conditions: Clinically Amyopathic Dermatomyisitis(CAMD)
Interventions: DRUG: Tofacitinib 5 MG [Xeljanz]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Head-to-head Study of 68Ga-MGS5 Versus 68Ga-DOTATATE PET/CT in Patients With Medullary Thyroid Carcinoma
Status: RECRUITING
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: 68Ga-MGS5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleep Quality After Stellate-ganglion Block of Patients Undergoing Breast Cancer Operation
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DRUG: 0.25% ropivacaine hydrochloride|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia
Status: UNKNOWN
Conditions: Sedation|Anesthesia, Spinal
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Urethral Cancer
Interventions: BIOLOGICAL: Recombinant Interferon Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Controlled Remifentanil Analgesia for Normal Labour
Status: WITHDRAWN
Conditions: Labor Pain|Full Term Pregnancy
Interventions: DRUG: Patient-controlled remifentanil analgesia|DRUG: Epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sequential Bacillus Calmette-Guérin (BCG) and Electromotive Mitomycin-C Versus Bacillus Calmette-Guérin (BCG) Alone for High Risk Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: bacillus Calmette-Guerin|DRUG: electromotive mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma
Status: UNKNOWN
Conditions: Nausea and Vomiting|Testicular Germ Cell Tumor
Interventions: DRUG: granisetron hydrochloride|DRUG: lerisetron|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Long-term Serum Magnesium and Potassium Levels Optimization and Multifactorial Adherence Intervention on the Progression of Diabetic Kidney Disease.
Status: UNKNOWN
Conditions: Diabetic Kidney Disease|Potassium Imbalance|Magnesium Deficiency
Interventions: OTHER: Multifactorial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions
Status: COMPLETED
Conditions: Cannabis, Drug Effects
Interventions: DRUG: CBD|DRUG: THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of MEDI-545 in Patients Who Have Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Lupus
Interventions: BIOLOGICAL: MEDI-545|BIOLOGICAL: MEDI 545|BIOLOGICAL: MEDI-545|BIOLOGICAL: MEDI-545|BIOLOGICAL: MEDI-545
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer
Status: TERMINATED
Conditions: Gynecologic Neoplasms|Epithelial Ovarian Cancer
Interventions: DRUG: PLX2853|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate Efficacy, Safety and Tolerability of FE 201836 for Nocturia Due to Nocturnal Polyuria in Adults
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: FE 201836|DRUG: Desmopressin|DRUG: Placebo oral solution|DRUG: Placebo ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Using a PET Gamma Probe to Evaluate Lymph Nodes in Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: PROCEDURE: lymphadenectomy|PROCEDURE: therapeutic conventional therapy|PROCEDURE: Positron Emission Tomography/ Computed Tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of Prednisolone and Chloroquine Add on Therapy in Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Glucosamine and chondroitin sulfate|DRUG: glucosamine and chondroitin sulfate plus Prednisolone|DRUG: Glucosamine and Chondroitin sulfate plus Chloroquine|DRUG: Glucosamine,Chondroitin sulfate,Prednisolone,Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Medium Cut-Off Dialyzer - Medical Device on ESA Resistance in 110 Hemodialysis Patients (EXPAND)
Status: UNKNOWN
Conditions: Hemodialysis Complication
Interventions: DEVICE: Medium cut-off dialyzer|DEVICE: High-flux dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AR08 for Treatment of ADHD in Children
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: AR08|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 'Cardiac and Intramuscular Adaptations Following Short-term Exercise Prehabilitation in Unfit Patients Scheduled to Undergo Hepatic- or Pancreatic Surgery'
Status: NOT_YET_RECRUITING
Conditions: Prehabilitation|Surgery|Exercise Prehabilitation|Perioperative Care
Interventions: DIAGNOSTIC_TEST: exercise MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Study: Dexmedetomidine Combined With Sufentanil for Patient Controlled Intravenous Analgesia After Caesarean Section
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Normal saline|DRUG: Dexmedetomidine|DRUG: Sufentanil|DRUG: Sufentanil and dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Acceptance and Commitment Therapy Versus Mindfulness-based Stress Reduction in Head and Neck Cancer
Status: UNKNOWN
Conditions: Cancer of Head and Neck
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Mindfulness-based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?
Status: COMPLETED
Conditions: End Stage Renal Disease|Hemodialysis
Interventions: OTHER: Catheter Lock Solution Taurolidine and Citrate|OTHER: Catheter Lock Solution :Taurolidine and Citrate and Heparin|OTHER: Catheter Lock Solution : Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: A Model of Computer-assisted Prescription of Erythropoiesis-stimulating Agents (ESA) in Patients Under Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: AI (model)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Gemcitabine, Bendamustine, and Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Classical Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Gemcitabine|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)
Interventions: DEVICE: NeoSync EEG Synchronization Therapy|DEVICE: Sham NeoSync EEG Synchronization Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating STA-9090 in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Ganetespib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Compared With Haloperidol in Patients With Chronic Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture on Diabetes-induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: DEVICE: laser acupuncture|DEVICE: sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Non Invasive Ventilation in Immuno-compromized Patients With Acute Respiratory Failure.
Status: COMPLETED
Conditions: Adult|Acute Respiratory Failure Admitted in ICU|Immuno Compromized
Interventions: PROCEDURE: Early non invasive ventilation|PROCEDURE: Oxygen therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt
Status: UNKNOWN
Conditions: Polycystic Kidney, Autosomal Dominant|ADPKD|Autosomal Dominant Polycystic Kidney
Interventions: DIETARY_SUPPLEMENT: Sodiumchloride|DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Placebo comparator (salt)|DIETARY_SUPPLEMENT: Placebo comparator (protein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Positron Emission Tomography (PET) Measurements of Fibrillar Amyloid Burden
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: [18F]AZD4694
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC