pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Analgesic Efficacy of Surgeon-administered Transversus Abdominis Plane Blocks for Caesarean Section.
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications|Pain, Postoperative
Interventions: OTHER: Surgeon-administered Transversus Abdominis Plane Block 0.25% bupivicaine 0.25 mL/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-GI Diet vs High-GI Diet in Individuals With SCI
Status: RECRUITING
Conditions: Spinal Cord Injuries|Postprandial Hypotension|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Low-GI Diet|DIETARY_SUPPLEMENT: High-GI Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Design and Piloting of a Complex Intervention to Support Breastfeeding Self-efficacy (CRIAA Program)
Status: COMPLETED
Conditions: Breastfeeding|Self Efficacy
Interventions: BEHAVIORAL: Breastfeeding support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution
Status: RECRUITING
Conditions: Cataract|Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost Implant System (High Dose)|DRUG: Bimatoprost Implant System (Low Dose)|DRUG: Timolol Maleate Ophthalmic Solution, 0.5%|DEVICE: Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL|DEVICE: SpyGlass IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab in Coronavirus-19 Positive Patients
Status: UNKNOWN
Conditions: Covid19|COVID-19|Severe Acute Respiratory Syndrome Coronavirus 2|Coronavirus|Inflammation
Interventions: BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip Surgery
Status: COMPLETED
Conditions: Intraoperative Blood Loss
Interventions: DRUG: Adrenaline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tiotropium Plus Salmeterol vs. Fluticasone/Salmeterol on Static Lung Volumes and Exercise Endurance in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium plus Salmeterol|DRUG: Fluticasone/Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Sole Local Anesthetic Versus Opioid Plus Local Anesthesia in Epidural Labor Analgesia
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Sole local anesthetic|DRUG: Sufentanil (Opioid plus local anesthetic)|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of the Use of Acupuncture for the Treatment of Spasticity in Chronic Stroke Participants
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Acupuncture|OTHER: Sham needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Safety.
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptability & Impact of a Diabetes Management Smartphone App (mySugr) for Spanish-literate Adults With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Smartphone diabetes management application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Preference Study
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: AL-3862+timolol ophthalmic suspension|DRUG: Dorzolamide+timolol ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Acupoint Stimulation(TEAS) for Postoperative Nausea and Vomiting in Laparoscopic Operation
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: TEAS (transcutaneous electrical acupoint stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on Study of Pentoxifylline in Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Meglumine antimonate|DRUG: Placebo|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Evaluating the Safety and Efficacy of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: COMBINATION_PRODUCT: SVd (Selinexor+Bortezomib+dexamethasone)|COMBINATION_PRODUCT: Vd (Bortezomib+dexamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Adjuvant Study for Stage III Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: UFT|DRUG: USEL/Leucovorin|DRUG: Krestin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Botulax® Versus Botox® in Patient With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Botulinum toxin type A injection|DRUG: Botulinum Toxin Type A Injection [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiome Post-Azythromycin/Albendazole Treatment
Status: WITHDRAWN
Conditions: Helminth Infection
Interventions: DRUG: Azithromycin|DRUG: Albendazole|DRUG: Delayed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Orthopedic Face Mask Use on Head Posture and Pharyngeal Airway
Status: COMPLETED
Conditions: Class III Malocclusion|Hyoid Bone
Interventions: DEVICE: Skeletal Class III Malocclusion Treatment with Face Mask Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of On1 Two-stage Abutment With One-stage Abutment on Different Implant Neck Design
Status: RECRUITING
Conditions: Implant Site Reaction
Interventions: DEVICE: On1 two-stage abutment and one-stage abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of 2 Transfusion Strategies on Quality of Life of Multitransfused Patients With Low-risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Transfusion-dependent Anemia
Interventions: OTHER: Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multimodal Image Study of Retinal Inflammation Markers After Corticoid and Antiangiogenic Treatment in Pacients With Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Antiangiogenic Agents|DRUG: Corticosteroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: pralatrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Online Acceptance and Commitment Therapy and Sound Therapy for Patients With Tinnitus and Insomnia
Status: RECRUITING
Conditions: Tinnitus|Insomnia
Interventions: BEHAVIORAL: ACT for tinnitus|OTHER: Customized sound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Stapled Versus Monocryl Sutured Skin Closure for Elective Open Colectomy
Status: UNKNOWN
Conditions: Wound Infection
Interventions: PROCEDURE: stapled skin closure|PROCEDURE: monocryl skin suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation in Chronic Hemodialysis Patients Versus Hemodialyzer Fiber Patency, Bleedings and Quality of Life
Status: COMPLETED
Conditions: Blood Coagulation
Interventions: OTHER: Hemodialyzer scanning|OTHER: Bleeding Questionnaires|OTHER: Quality of life questionnaire|OTHER: Visual inspection of the limbs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Cabazitaxel and Paclitaxel in HER2 Negative Breast Cancer
Status: RECRUITING
Conditions: HER2 Negative Metastatic Breast Cancer
Interventions: DRUG: Cabazitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: PF-07868489|DRUG: Placebo for PF-07868489
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Technology That Permits Focal Dose of Antibiotics to be Delivered to Lower Limb(s) of Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Infection
Interventions: PROCEDURE: Percutaneous Isolated Limb Perfusion (PILP) delivery|DRUG: Timentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Quadrivalent Influenza Vaccine (NBP607-QIV) in Adults and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: NBP607-QIV|BIOLOGICAL: NBP607-Y|BIOLOGICAL: NBP607-V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Annual Study to Investigate Inactivated Subunit Influenza Vaccine Due to New Virus Strains for the 09/10 Season
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza subunit vaccine Influvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of PSAPs in Different Maskers
Status: COMPLETED
Conditions: Auditory Perception
Interventions: DEVICE: Sound World Solutions CS50+|DEVICE: Tweak Focus|DEVICE: IQ Earbuds|DEVICE: Bose Hearphones
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease
Status: COMPLETED
Conditions: Liver Disease|Cirrhosis of the Liver|Acute-On-Chronic Liver Failure|Liver Failure
Interventions: OTHER: blood sampling for research purpose|OTHER: clinical data collection|OTHER: Health-related Questionnaires|OTHER: Sampling other biological materials (e.g. liver biopsies, liver resections, ascites, urine, gut biopsies)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Melatonin and Clonazepam for IRBD
Status: COMPLETED
Conditions: REM Sleep Behavior Disorder
Interventions: DRUG: Melatonin 2mg|DRUG: ClonazePAM 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Carcinoma|Prostate Small Cell Neuroendocrine Carcinoma|Stage III Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: DRUG: Bendamustine|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Bridge Therapy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|PROCEDURE: Echocardiography|DRUG: Fludarabine|PROCEDURE: Leukapheresis|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: T-cell Receptor-engineered T-cells|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Plasma Therapy for Acceleration of Wound Healing in Diabetic Foot
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot
Interventions: DEVICE: Argon Plasma Jet|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Swedish Rectal Prolapse Trial
Status: TERMINATED
Conditions: Rectal Prolapse
Interventions: PROCEDURE: Suture rectopexy|PROCEDURE: resection rectopexy|PROCEDURE: Delorme's operation|PROCEDURE: Altemeier's operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine(s) GSK3206641A and GSK3206640A Administered in Adults 18 to 64 Years of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Investigational H7N9 vaccine GSK3206641A|BIOLOGICAL: Investigational H7N9 vaccine GSK3206640A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: CMK389|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized, Double Blind Study Comparing IV vs PO Acetaminophen in Patients Undergoing Lumbar Discectomy
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: oral acetaminophen|DRUG: intravenous acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Surgical Management of Idiopathic Normal Pressure Hydrocephalus (INPH)
Status: TERMINATED
Conditions: Normal Pressure Hydrocephalus
Interventions: PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Follicular|Lymphoma, Mantle-Cell|Lymphoma, Small-Cell|Waldenstrom Macroglobulinemia|Lymphoma, B-Cell, Marginal Zone
Interventions: DRUG: Rituximab|DRUG: Bendamustine|DRUG: Vincristine sulfate liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rasagiline on Cognition in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Adjuvant Medical Treatment of Peritoneal Endometriosis on the Outcome of IVF. A Prospective Randomized Analysis.
Status: COMPLETED
Conditions: Infertility|Endometriosis
Interventions: DRUG: Zoladex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Low-level Laser Therapy in the Acute Treatment of Migraine
Status: UNKNOWN
Conditions: Migraine Headache
Interventions: DEVICE: Argus Migraine Treatment device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Patient Reported Outcomes in Patients With Gastrointestinal Cancers
Status: WITHDRAWN
Conditions: Gastrointestinal Cancers|Gastrointestinal Cancer Metastatic
Interventions: OTHER: Electronic Patient Reported Outcomes platform|OTHER: Health Related Quality of Life Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tissue Immune Interaction in Nasal Polyposis
Status: RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)|Chronic Rhinosinusitis With Nasal Polyps|Asthma
Interventions: PROCEDURE: Sinonasal Debridement Procedure|PROCEDURE: Nasal Polyp Removal|PROCEDURE: Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sipuleucel-T and Low-protein Diet in Patients With Metastatic Castrate-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Recurrent
Interventions: OTHER: Low protein diet|OTHER: Control protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Adapalene Gel 0.3% to Differin® and Both to a Placebo Control in Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene Gel 0.3%|DRUG: Differin®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contour Augmentation by Means of Connective Tissue Grafting Versus Guided Bone Regeneration
Status: COMPLETED
Conditions: Guided Bone Regeneration
Interventions: PROCEDURE: Hard tissue augmentation at the buccal aspect of single implants.|PROCEDURE: Soft tissue augmentation at the buccal aspect of single implants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: ALK Gene Rearrangement|EGFR Gene Mutation|Locally Advanced Lung Non-Small Cell Carcinoma|Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spatial Repellents for Malaria Control
Status: NOT_YET_RECRUITING
Conditions: Malaria
Interventions: DEVICE: Transfluthrin - delivery by paid study personnel|DEVICE: Transfluthrin - delivery by voucher system|DEVICE: Transfluthrin - delivery by village health teams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eutectic Mixture for Hemorrhoidectomy Postoperative
Status: UNKNOWN
Conditions: Hemorrhoidectomy
Interventions: DRUG: Eutectic mixture|DRUG: placebo|DRUG: lidocaine 2,5%; prilocaine 2,5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of New Non-invasive Prenatal Tests for Screening for Fetal Trisomies Using Maternal Blood
Status: COMPLETED
Conditions: Trisomy 21|Trisomy 18|Trisomy 13
Interventions: OTHER: Integrated prenatal screening for Down's syndrome|OTHER: Serum QUAD Assay for aneuploidy screening|OTHER: Semiconductor MPSS NIPT assay using ccfDNA in maternal blood|OTHER: Optical-based MPSS NIPT assay using ccfDNA in maternal blood|OTHER: Harmony™ Test (Ariosa Diagnostics)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Probiotics as Adjuvant Therapy in the Treatment of Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DIETARY_SUPPLEMENT: Omni-Biotic 10|DRUG: loperamide ("Seldiar")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of GlaxoSmithKline (GSK)134612 in Subjects With Increased Risk for Meningococcal Disease Versus Healthy Subjects
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: eHealth Insomnia Intervention for Adult Survivors of Childhood Cancer
Status: RECRUITING
Conditions: Childhood Cancer|Insomnia|Neurocognitive Impairment|Survivorship|Late Effect|Sleep
Interventions: DEVICE: Sleep Healthy Using the Internet (SHUTi) Intervention Group|DEVICE: Online Patient Education (PE) Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Prognostic Impact of Selenium On Critical Surgical Patients
Status: COMPLETED
Conditions: Critical Illness|Selenium Deficiency|Trace Element Deficiency|Acute Abdomen|Sepsis
Interventions: DRUG: Selenium Supplement|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the Impact of a Nutritional Beverage on Tests of Memory in Healthy Preschool Age Children
Status: COMPLETED
Conditions: Cognition
Interventions: OTHER: Test beverage powder (High Proteins and added micronutrients)|OTHER: Control beverage powder (Low protein and no added micronutrients)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs
Status: UNKNOWN
Conditions: Unsatisfactory Restoration of Tooth|Carious Teeth
Interventions: PROCEDURE: shoulder finishline|PROCEDURE: butt joint with bevel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males
Status: COMPLETED
Conditions: High-grade Anal Intraepithelial Neoplasia
Interventions: PROCEDURE: electrocoagulation|DRUG: cidofovir 1% topical ointment|DRUG: sinecatechins 10% topical ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Effectiveness of the Hydrus Microstent (TM) to Two iStents to Lower IOP in Phakic Eyes
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Pseudoexfoliative Glaucoma|Pigmentary Glaucoma
Interventions: DEVICE: Hydrus Microstent|DEVICE: iStent Trabecular Micro Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation
Status: WITHDRAWN
Conditions: Aortic Aneurysm, Abdominal|Carotid Atherosclerosis
Interventions: DRUG: 18F-FPPRGD2|DEVICE: Positron emission tomography|PROCEDURE: Computed tomography|DEVICE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Influence of Diet on GI Health
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: High-fiber, low-protein diet|OTHER: Low-fiber, high-protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot RCT Evaluating a One Stop Vein Clinic
Status: TERMINATED
Conditions: Varicose Veins
Interventions: OTHER: One Stop Vein Clinic|DEVICE: Radiofrequency ablation|DEVICE: Endovenous laser ablation|DRUG: Foam sclerotherapy (Polidocanol or Sodium Tetradecyl Sulphate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omega-3 Fatty Acid Supplements and Dry Eye
Status: TERMINATED
Conditions: Keratoconjunctivitis Sicca
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid|DIETARY_SUPPLEMENT: Soybean Soft Gels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Evaluation of Four Non-operative Treatments for Degenerative Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: BEHAVIORAL: Self-management Program, Workbook, Video, Pedometer|BEHAVIORAL: Instructional Workbook, Video, and Pedometer|DEVICE: Para-spinal TENS|DEVICE: Para-spinal Placebo TENS|DEVICE: Prototype Spinal Stenosis Belt|DEVICE: Sham Spinal Stenosis Belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective Study
Status: UNKNOWN
Conditions: Sarcoma, Soft Tissue|Osteosarcoma Tumor
Interventions: BEHAVIORAL: Neuropsychological assessment, MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Home-based Cardiac Rehabilitation for People Living With Heart Failure and Their Caregivers- The DK:REACH-HF Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Home-based cardiac rehabilitation for people living with Heart Failure and their caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: kalifilcon A Daily Disposable Toric|DEVICE: Ultra for Astigmatism Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cannabis for Pain and Inflammation in Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: Smoked Cannabis High CBD/low THC|DRUG: Smoked Placebo Cannabis Low CBD/low THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic Kidney Disease
Status: RECRUITING
Conditions: Diabetic Nephropathies|Diabetes Mellitus, Type 2|Chronic Kidney Diseases|Healthy Lifestyle
Interventions: BEHAVIORAL: Individualized basic need navigation and lifestyle coaching and skills training|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Half-thickness Tragal Cartilage Graft vs Temporalis Fascia Graft Tympanoplasty Type I
Status: COMPLETED
Conditions: Hearing Loss,Conductive
Interventions: PROCEDURE: Tympanoplasty using tragal cartilage graft|PROCEDURE: Tympanoplasty using temporalis fascia graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Study of Mucositis Prevention After Radiochemotherapy Treatment for Head and Neck Cancer
Status: COMPLETED
Conditions: Severe Acute Mucositis|Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: Oral Impact|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Relative Oral Bioavailability of Single Dose Administration of TMC207, Under Fed and Fasted Conditions in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Understand How The Body Reacts To A Low Dose Of PF-06427878 When Given In A Vein To Healthy, Adult, Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06427878
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer
Status: RECRUITING
Conditions: Lung Carcinoma
Interventions: PROCEDURE: Participants smoke their usual brand of cigarettes for 26 weeks.|PROCEDURE: Participants will vape electronic cigarettes for 26 weeks.|DRUG: Nicotine Replacement|DRUG: Nicotine Replacement|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitrite Supplementation for Improving Physiological Function in Older Adults
Status: COMPLETED
Conditions: Ageing
Interventions: DRUG: Sodium nitrite|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
Status: RECRUITING
Conditions: Stroke|Depression, Anxiety|Coping Skills|Couples
Interventions: BEHAVIORAL: ReStoreD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pelvic Floor Muscle Exercises and Core Exercises in Menopausal Women
Status: RECRUITING
Conditions: Menopause|Stress Urinary Incontinence|Kegel Exercises|Core Strength
Interventions: OTHER: Pelvic Floor Muscle Exercise|OTHER: Core Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Intervention for Reduction of Ultra-processed Products and Increase of Physical Activity in University Students
Status: NOT_YET_RECRUITING
Conditions: Physical Inactivity|Ultra Processed Food|Stress|Anxiety|Depression
Interventions: BEHAVIORAL: Unisalud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study for the Treatment of Atherosclerotic Lesions in the Superficial Femoral and/or Popliteal Arteries Using the FLEX Scoring Catheter Plus DCB
Status: TERMINATED
Conditions: Peripheral Artery Disease
Interventions: COMBINATION_PRODUCT: FLEX Dynamic Scoring Catheter with IN.PACT Admiral DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: Compensatory auditory stimulation|DEVICE: transcranial direct current stimulation|OTHER: Combined CAS and tDCS|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS and Advanced ARC Patients With Anemia
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Different Fasting Blood Glucose Targets on Glucose Control in Patients With Type 2 Diabetes Using Insulin Detemir Once Daily
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Juno Perth Clinical Trial
Status: TERMINATED
Conditions: Respiratory Insufficiency|Obesity Hypoventilation Syndrome|Chronic Obstructive Pulmonary Disease (COPD)|Neuromuscular Disease|Upper Airway Obstruction
Interventions: DEVICE: Juno|DEVICE: Juno|DEVICE: Juno
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6765 Severe Major Depressive Disorder (MDD) IV
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: AZD6765|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Solid Tumor|Melanoma|Renal Cell Carcinoma|Triple-negative Breast Cancer|Non Small Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck|Carcinoma|MSI-High
Interventions: BIOLOGICAL: ST-067|BIOLOGICAL: Obinutuzumab 25 MG/1 ML Intravenous Solution [GAZYVA]|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tripod-Fix Vertebral Body Augmentation System in Osteoporotic Vertebral Compression Fractures Treatment
Status: RECRUITING
Conditions: Osteoporotic Vertebral Compression Fractures
Interventions: DEVICE: Tripod-Fix Vertebral Body Augmentation System (Tripod-Fix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Emotional Skills of Young Women and Their Partner on Adjustment to Cancer
Status: UNKNOWN
Conditions: Aging|Breast Cancer
Interventions: OTHER: Delivery of questionnaires|BEHAVIORAL: Questionnaire T1 to fill|BEHAVIORAL: Questionnaire T2 to fill|BEHAVIORAL: Questionnaire T3 to fill|BEHAVIORAL: Questionnaire T4 to fill|BEHAVIORAL: Questionnaire T5 to fill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of SCS and PMR in Patients With Refractory Angina Pectoris
Status: TERMINATED
Conditions: Angina Pectoris
Interventions: PROCEDURE: Spinal Cord Stimulation (SCS)|PROCEDURE: Percutaneous Myocardial Laser Revascularisation (PMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Step it Up: An Exercise and Behaviour Change Programme for People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Exercise + behaviour change intervention|BEHAVIORAL: Exercise + control education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Randomized Double-blind Clinical Study Evaluated the Safety, Pharmacokinetic and Pharmacodynamic Characteristics of Roflumilast in COPD Patients
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Sleep Intervention to Traditional Diet and Exercise Approach to Weight Loss
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Obesity
Interventions: BEHAVIORAL: Diet and exercise|BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Passion and Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Tolerability of Titrated Dose Tramadol/Acetaminophen Combination Tablet in Korean Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: tramadol hydrochloride /acetaminophen|DRUG: tramadol hydrochloride / acetaminophen and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Alternate Dosing Schedules Study for HPV Vaccine (ADS)
Status: COMPLETED
Conditions: Cervical Cancer|Genital Warts
Interventions: BIOLOGICAL: Both 2nd and 3rd doses on time|BIOLOGICAL: 2nd dose late and 3rd dose on time|BIOLOGICAL: 2nd dose on time and 3rd dose late|BIOLOGICAL: Both doses late
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study for SIR-Spheres Therapy for the Treatment of Unresectable Metastatic Liver Tumors From Primary Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DEVICE: Resin microspheres containing yttrium-90 (Y-90)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrical Stimulation and Vaginal Palpation in Pelvic Floor Muscles Awareness
Status: UNKNOWN
Conditions: Pelvic Floor Disorders
Interventions: OTHER: Transvaginal electrical stimulation|OTHER: Palpation|OTHER: Palpation with posterior pelvic tilt|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesiotaping for Hands Function in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Conventional Physical Therapy)|OTHER: Kinesiotaping with I shaped application|OTHER: Kinesiotaping with Fan-shaped Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Neurocognition Enhancing Agent in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abilify in Bipolar Disorder for 6 Weeks Treatment Effectiveness
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Abilify(Aripiprazole)|DRUG: Depakote(Divalproate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Phone-Based Smoking-Cessation Intervention for Chronic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Initial phase: Personalized Chat Support (PCS)|BEHAVIORAL: Second phase: Multi-component Optional Support (MOS)|BEHAVIORAL: Initial phase: Group Chat Support (GCS)|BEHAVIORAL: Second phase: Personalized Chat Support (PCS)|BEHAVIORAL: 5A's / 5R's advice|BEHAVIORAL: health warning leaflet|BEHAVIORAL: Self-help booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase II, Open-Label, Multicenter Trial of Cabazitaxel in Patients With Recurrent or Metastatic Head and Neck Cancer After Failure Of Cisplatin, Cetuximab and Taxanes
Status: COMPLETED
Conditions: Recurrent Head and Neck Cancer|Metastatic Head and Neck Cancer
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT)
Status: COMPLETED
Conditions: HIV Infections|CMV Cytomegalovirus Retinitis
Interventions: DRUG: Cidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants in Japan With Generalized Pustular Psoriasis and Erythrodermic Psoriasis
Status: COMPLETED
Conditions: Generalized Pustular Psoriasis|Erythrodermic Psoriasis
Interventions: DRUG: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Thoracic Erector Spinae Plane Blockade on Acute and Chronic Pain After Video Assisted Thoracoscopic Surgery (VATS)
Status: UNKNOWN
Conditions: Thoracic
Interventions: DRUG: ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI
Status: RECRUITING
Conditions: Gulf War Illness
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Stinging Nettle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Latino Semaglutide Study
Status: RECRUITING
Conditions: Obesity|Obesity; Drug|Overweight or Obesity|Weight Loss|Weight Loss Trajectory|Weight, Body
Interventions: DRUG: Semaglutide 2.4mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Energy Restriction and Omega-3 Fatty Acids on Mammary Tissue
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Lovaza|OTHER: Dietary energy restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intracoronary Progenitor Cell Therapy on Coronary Flow Reserve After Acute MI
Status: TERMINATED
Conditions: Coronary Artery Disease|Acute Myocardial Infarction
Interventions: BIOLOGICAL: autologous bone marrow-derived progenitor cells|BIOLOGICAL: placebo medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sahlgrenska Cardiomyopathy Project
Status: ENROLLING_BY_INVITATION
Conditions: Dilated Cardiomyopathies|Hypertrophic Cardiomyopathy|Restrictive Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy|Myocarditis|Sarcoidosis With Myocarditis|Giant Cell Myocarditis|Amyloidosis; Heart (Manifestation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p