pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low Level Laser Therapy and Expression of VEGF, NO, VEGFR-2, HIF-1α in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Low Level Laser(Ga-As)|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: exemestane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Operative Water Load Following Transsphenoidal Pituitary Surgery
Status: COMPLETED
Conditions: Hyponatremia|Pituitary Adenoma
Interventions: OTHER: Water Load (WL) Post-Operative Day 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Effects of Short Term Sugarcane Bagasse Supplementation
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: OTHER: Sugarcane bagasse|OTHER: Non-caloric, non-fermentable fiber|OTHER: Minimal fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Healing After Connective Tissue Graft Harvesting in the Palatal Area With and Without Suture
Status: COMPLETED
Conditions: Wound Healing
Interventions: PROCEDURE: Subepithelial connective tissue graft (SCTG) using the single incision technique, with and without suturing the palate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: topical local anesthesia of pulmonary vein combined with vagus nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathic Pain
Interventions: DEVICE: intermittent pneumatic compression +pregabalin group|OTHER: pregabalin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of an Antibody Against Yellow Fever Virus (TY014) in Humans
Status: COMPLETED
Conditions: Treatment of Acute Yellow Fever Virus Infection
Interventions: BIOLOGICAL: TY014|OTHER: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of WALKBOT-G Robot-assisted Gait Training on Anticipatory Posture Adjustment Function and Balance With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic Hemiplegic Cerebral Palsy|Bilateral Spastic Cerebral Palsy|Gait Disorders, Neurologic
Interventions: DEVICE: robot-assisted gait training|BEHAVIORAL: conventional locomotion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine 5% Medicated Plaster in Chronic Neuropathic Postoperative Pain
Status: TERMINATED
Conditions: Pain|Chronic Pain|Neuropathic Pain|Postoperative Pain
Interventions: DRUG: Lidocaine 5% medicated plaster|DRUG: Placebo topical plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Neural Circuit Biomarkers of Major Depression Response to CCBT
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Major Depressive Disorder|Depressive Disorder|Depression, Unipolar
Interventions: BEHAVIORAL: Computer-Augmented Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma|Recurrent Gliosarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacodynamics Study of AGN-207281 Ophthalmic Solutions Compared With Timolol Ophthalmic Solution or Placebo in Patients With Ocular Hypertension or Primary Open-Angle Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: AGN-207281 ophthalmic solutions (0.1% and 0.3%); AGN-207281 vehicle ophthalmic solution (placebo)|DRUG: timolol ophthalmic solution 0.5%|DRUG: AGN-207281 vehicle ophthalmic solution (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Response Adapted Therapy With Bortezomib/Dexamethasone Followed by Addition of Lenalidomide in Non Responders as Initial Treatment for Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma (MM)
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Preterm Infants - The Efficacy of Internet-based Peer Support
Status: COMPLETED
Conditions: Breast Feeding|Infant, Premature
Interventions: BEHAVIORAL: Breastfeeding peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes in Lab and Ultrasonography After Endoscopic Varisceal Treatment
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DIAGNOSTIC_TEST: Liver function tests (ALT,AST,ALBUMIN,BILIRUBIN,INR,PC,CBC)|DEVICE: biannual ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories
Status: COMPLETED
Conditions: Ulcerative Proctitis
Interventions: COMBINATION_PRODUCT: Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator|COMBINATION_PRODUCT: Once daily 90 mg hydrocortisone acetate or placebo suppository administered with Sephure applicator|COMBINATION_PRODUCT: Twice daily placebo suppository administered with Sephure applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Laser Therapy in Patients With Sacroiliitis
Status: RECRUITING
Conditions: Sacroiliac Arthritis
Interventions: DEVICE: High-Intensity Laser Therapy (HILT)|DEVICE: Sham High-Intensity Laser Therapy (HILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Stroke
Interventions: OTHER: Tight control of end-tidal CO2 levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Bias Modification Training for Social Phobia (ABMSP)
Status: RECRUITING
Conditions: Social Anxiety Disorder
Interventions: OTHER: Attentional Bias Modification Training (ABMT)|OTHER: General Attention Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: Omaveloxolone|DRUG: Midazolam oral solution|DRUG: Repaglinide 1 MG|DRUG: MetFORMIN 500 Mg Oral Tablet|DRUG: Rosuvastatin|DRUG: Digoxin tablet|DRUG: Gemfibrozil Tablets|DRUG: Itraconazole capsule|DRUG: Verapamil Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radical Cystectomy, Nutrition and Convalescence
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms|Cystectomy|Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: Parenteral nutrition. SMOFKABIVEN infusion in central vene. Fresenius Kabi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Treatment With CHOP and Lenalidomide in First Line in Angioimmunoblastic T-cell Lymphoma (AITL)
Status: COMPLETED
Conditions: T-cell Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Adult Spinal Deformity Surgery
Status: RECRUITING
Conditions: Spinal Deformity|Degenerative Lumbar Spinal Stenosis|Blood Loss, Surgical
Interventions: DRUG: Tranexamic Acid 100 MG/ML|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Estradiol Vaginal Cream to Estrace® Cream in 350 Postmenopausal Females With Atrophic Vaginitis
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DRUG: Estradiol Vaginal Cream, 0.01%|DRUG: Estrace® 0.01% cream|DRUG: Placebo Vaginal Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft
Status: COMPLETED
Conditions: Bone Augmentation
Interventions: DEVICE: Ridge preservation using DFDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Efficacy and Safety of BIO89-100 (Pegozafermin) in Participants With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Pegozafermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers
Status: UNKNOWN
Conditions: Hyperalgesia
Interventions: DRUG: Remifentanil|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dysphagia in Cardiac Surgical Patients_
Status: WITHDRAWN
Conditions: Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Fiberoptic Endoscopic Evaluation of Swallowing|DIAGNOSTIC_TEST: Simultaneous FEES and Videofluoroscopy instrumental swallowing exam|OTHER: Voluntary Cough Peak Expiratory Flow (PEF) Testing|OTHER: Reflex Cough Screen|OTHER: Lingual Pressure Testing|DIAGNOSTIC_TEST: Speech Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab and GM-CSF in Treating Patients With Newly Diagnosed Follicular B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: Sargramostim (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I-II Vaccination of Autologous Dendritic Cells Transduced With Adenoviral Vector Encoding NS3 in Hepatitis C Encoding NS3 in Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Autologous dendritic cells transduced with Ad encoding NS3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute, Rapid Lowering of LDL Cholesterol With Alirocumab in Patients With STEMI Undergoing Primary PCI
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction|Acute Coronary Syndrome|Hypercholesterolemia|Hyperlipidemias|Dyslipidemias|Physiological Effects of Drugs
Interventions: DRUG: Alirocumab|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Hilo Pilot -Trial to Assess Feasibility
Status: COMPLETED
Conditions: Premature Infant|Respiratory Distress Syndrome
Interventions: PROCEDURE: 30% group|PROCEDURE: 60% group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States
Status: NOT_YET_RECRUITING
Conditions: Suspected or Known Squamous Cell Neoplasia|Prior History of Squamous Cell Dysplasia and /or Neoplasia
Interventions: DRUG: Proflavine Hemisulfate|DEVICE: Artificial Intelligence Mobile High-Resolution Microendoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Thoracic paravertebral block (TPVB)|DRUG: Patient Controlled Analgesia (IV PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MCI-196 in Chronic Kidney Disease Subjects on Dialysis With Hyperphosphatemia and Dyslipidaemia
Status: COMPLETED
Conditions: Chronic Kidney Disease|Dialysis|Hyperphosphatemia|Dyslipidemia
Interventions: DRUG: MCI-196|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Whether the Combination of Two Immunotherapy Drugs Have Activity in Recurrent or Persistent Clear Cell Ovarian Cancer
Status: COMPLETED
Conditions: Malignant Ovarian Clear Cell Tumor|Recurrent Ovarian Carcinoma
Interventions: DRUG: Epacadostat|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Immunity Persistence Study of Booster Dose of Live Attenuated Varicella Vaccine
Status: NOT_YET_RECRUITING
Conditions: Varicella
Interventions: BIOLOGICAL: Live Attenuated Varicella Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Advanced Pancreatic Adenocarcinoma|Unresectable Pancreatic Cancer|Ductal Adenocarcinoma of the Pancreas
Interventions: DRUG: AGuIX|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care Measurements of Platelet Inhibition After Clopidogrel Loading in Patients With Acute Coronary Syndrome: Comparison of Generic Clopidogrel Bisulfate (Plavitor®) With Original Clopidogrel Bisulfate (Plavix®)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: generic clopidogrel (Plavitor® )|DRUG: original clopidogrel (Plavix® )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Buscopan Plus in Painful Gastric or Intestinal Spasms
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DRUG: Buscopan® plus|DRUG: Buscopan®|DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Trial of Dapaconazole Versus Ketoconazole
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Dapaconazole|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Epoetin Alfa Plus Standard Supportive Care Versus Standard Supportive Care Only in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Neoplasm Metastasis
Interventions: OTHER: Standard supportive care (packed RBC transfusion)|DRUG: epoetin alfa + packed RBC transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise for Physical Health in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm|Osteoporosis
Interventions: BEHAVIORAL: Resistance Exercise|BEHAVIORAL: Flexibility Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 24-Hour Intraocular Pressure With Brinzolamide/Timolol Versus Brimonidine/Timolol
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Brimonidine/timolol fixed combination drops added to travoprost|DRUG: Brinzolamide/timolol fixed combination drops added to travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Safety and Efficacy of Two Dosing Regimens of ABT-874 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Placebo|BIOLOGICAL: ABT-874|BIOLOGICAL: ABT-874
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Milciclib in Patients With Unresectable/Metastatic Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Milciclib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Systemic Absorption of Menadione Topical Lotion for Epidermal-Growth-Factor-Receptor (EGFR) Inhibitor-Associated Rash
Status: COMPLETED
Conditions: EGFR Inhibitor-associated Rash
Interventions: DRUG: Menadione Topical Lotion|DRUG: Menadione Topical Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrate, Chronic Obstructive Pulmonary Disease (COPD) and Exercise
Status: COMPLETED
Conditions: COPD
Interventions: DIETARY_SUPPLEMENT: Beetroot|DIETARY_SUPPLEMENT: Beetroot placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: State-wide Health Approach to Increase Reach and Effectiveness: Study 3
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Shape Up Rhode Island|BEHAVIORAL: Shape Up Rhode Island + Professional Coach + Incentives|BEHAVIORAL: Shape Up Rhode Island + Peer Coach + Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids
Status: TERMINATED
Conditions: Constipation
Interventions: DRUG: Naloxegol Oral Tablet|DRUG: Placebo Oral Tablet|DRUG: Docusate Sodium 100 Mg oral capsule [Colace]|DRUG: Senna 217 Mg Oral Tablet|DRUG: Polyethylene Glycols|DRUG: Bisacodyl 10 mg Suppository|DRUG: Magnesium Citrate Oral Liquid Product|DRUG: Methylnaltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endodontic Post-operative Pain Evaluation of Patients After Using Endomethasone N or Endomethasone SP (EndoPOP)
Status: COMPLETED
Conditions: Root Canal Obturation
Interventions: DEVICE: Endomethasone N RCS|DEVICE: Endomethasone SP RCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carboxyamidotriazole in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: carboxyamidotriazole|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Induction Effects on Stabilometry Versus Sham Laser
Status: COMPLETED
Conditions: Foot Diseases|Myofascial Pain
Interventions: OTHER: Sham Laser|OTHER: Myofascial Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: ARTESUNATE + AMODIAQUINE|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Combination With Rituximab in Treating Participants With Stage III/IV Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage III Marginal Zone Lymphoma|Ann Arbor Stage III Small Lymphocytic Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Indolent Adult Non-Hodgkin Lymphoma|Ann Arbor Stage IV Marginal Zone Lymphoma|Ann Arbor Stage IV Small Lymphocytic Lymphoma
Interventions: DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: dexmedetomidine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Primary Hormone Receptor Positive Breast Cancer
Interventions: OTHER: Exercise Treatment|OTHER: Plant-Based Diet|OTHER: Physical activity|OTHER: Nutrition counseling|OTHER: Replication Exercise Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medial vs Lateral Approach for Total Knee Replacement on Valgus Knee: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: Medial approach|PROCEDURE: Keblish approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Calisthenic Exercise on Aerobic Capacity, Muscle Strength and Quality of Life in Hemodialysis Patients
Status: COMPLETED
Conditions: Physical Activity|Patient|Quality of Life|Hemodialysis
Interventions: OTHER: Calisthenic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Brain Mechanisms of Reducing Polysubstance Use
Status: RECRUITING
Conditions: Multiple Drug Use
Interventions: BEHAVIORAL: IBMT|BEHAVIORAL: NF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label Maintenance Study of the Enzyme Replacement Therapy Replagal in Patients With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: Replagal agalsidase alfa|DRUG: Replagal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bowel|Neurogenic Bladder Dysfunction
Interventions: DEVICE: Sacral electromyography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vildagliptin Glycemic Profiles Assessment Using a Continuous Glucose Monitoring Device.
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: Vildagliptin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of Meplazumab in Healthy Volunteer
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: meplazumab for injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Stereotactic Radiotherapy in Locally Advanced Pancreatic Cancer With Different Biological Effective Doses
Status: UNKNOWN
Conditions: Treatment
Interventions: RADIATION: SBRT|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: Efgartigimod PH20 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Comparison Study of Vibrating Mesh Versus Standard Jet Nebuliser for Bronchodilator Delivery in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: vibrating mesh nebuliser|DEVICE: Standard hospital jet nebuliser|DRUG: Combined salbutamol 2.5 mg and ipratropium 0.5mg nebule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Thrombocythemia
Interventions: BIOLOGICAL: Ropeginterferon alfa-2b|DRUG: Anagrelide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Frequent sit-to-stands|BEHAVIORAL: Walking breaks|BEHAVIORAL: Stand more
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
Status: NOT_YET_RECRUITING
Conditions: Pain|Aging
Interventions: DEVICE: RHA® Redensity with new anesthetic agent|DEVICE: RHA® Redensity with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Elastin Markers Synthesis in Williams-Beuren Syndrome and 7q11.23 Micro-duplication Syndrome
Status: UNKNOWN
Conditions: Williams-Beuren Syndrome|Micro-duplication 7q11.23 Syndrome|Vasculopathy
Interventions: BIOLOGICAL: Physical examination and Urine and blood samples|BIOLOGICAL: Urine and blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fat Emulsion in Preventing Hypersensitivity Reactions in Patients With Cancer Receiving Carboplatin or Oxaliplatin
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm
Interventions: DIETARY_SUPPLEMENT: Fat Emulsion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Moxibustion for Mild and Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: herb-partitioned moxibustion|OTHER: bran-partitioned moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability of Chlorogenic and Phenolic Acids From Soluble Coffees
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Coffee bioavailability trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relative Bioavailability Study of Marketed and Lower Dose Ambrisentan in Healthy Adult Participants
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: AMB new formulation (1 mg)|DRUG: Reference AMB (5 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Carcinoma|Recurrent Uterine Corpus Carcinoma|Stage IIIA Uterine Corpus Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC1 Uterine Corpus Cancer|Stage IIIC2 Uterine Corpus Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Uterine Corpus Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Megestrol Acetate|DRUG: Tamoxifen Citrate|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: PROCEDURE: Intensity modulated radiotherapy (IMRT)|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rheos® Pivotal Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Rheos® Baroreflex Hypertension System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: XEN-D0501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: " En Face " OCT's Contribution in the Detection of Macular Retinal Toxicity Signs Linked to the Chronic Treatment of Synthetic Antimalarials
Status: COMPLETED
Conditions: Maculopathy
Interventions: DEVICE: spectral domain optical coherence tomography|DEVICE: multifocal electroretinogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Flunarizine for Treatment Resistant Absence Epilepsy
Status: TERMINATED
Conditions: Childhood Absence Epilepsy|Juvenile Absence Epilepsy|Juvenile Myoclonic Epilepsy
Interventions: DRUG: Flunarizine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sintilimab in Combination With Chemoradiothrapy Followed by D2 Surgical Resection in Patients With Advanced Gastric Cancer With Retroperitoneal Lymph Node Metastasis
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Sintilimab|DRUG: Albumin-Paclitaxel|DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: Radiation|PROCEDURE: Radical gastric cancer surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide Capsules vs. Mesalazine Granules vs. Placebo in Collagenous Colitis
Status: COMPLETED
Conditions: Collagenous Colitis
Interventions: DRUG: Budesonide|DRUG: Mesalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness
Status: RECRUITING
Conditions: Consciousness Disorder|Minimally Conscious State|Vegetative State
Interventions: DEVICE: Active taVNS|DEVICE: sham taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Efficacy and Safety of Lando® Absorbable Collagen Membrane in Oral Bone Repair
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: DEVICE: Lando® absorbable collagen membrane|DEVICE: Geistlich Bio-Gide resorbable bilayer membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MCAT With HA and sCTG Compared With sCTG Alone for Treatment of Multiple Gingival Recession: Clinical Trial
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: DEVICE: The tunnel technique for root coverage with CTG without Cross-linked Hyaluronic Acid|DEVICE: The tunnel technique for root coverage with CTG andCross-linked Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: BL-8040|DRUG: Pembrolizumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ipilimumab and Dasatinib Combination Therapy in Patients With Chronic or Accelerated Chronic Myeloid Leukemia
Status: WITHDRAWN
Conditions: Leukemia, Myeloid, Chronic
Interventions: BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow-Derived Mesenchymal Stem Cell Therapy for Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Allogeneic adipose-derived mesenchymal stem cells (MSC)|DRUG: Allogeneic adipose-derived mesenchymal stem cells (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyphenol Enriched Extra-virgin Olive Oil and Postprandial Glycemia in Type 1 Diabetes (DOP)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: EVOO+POLY|OTHER: OO-POLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orphenadrine and Methocarbamol for LBP
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Orphenadrine|DRUG: Methocarbamol|DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of SB Cell for the Enhanced Osseointegration of Guided Bone Regeneration in Implant Surgery
Status: UNKNOWN
Conditions: Guided Bone Regeneration
Interventions: DRUG: SB cells|DRUG: SB cells|DRUG: SB cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationships Between the Noradrenergic, Opioid and Pain System
Status: WITHDRAWN
Conditions: Experimental Pain Perception
Interventions: DRUG: Clonidine|DRUG: Naloxone|DRUG: placebo|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. .
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Mineral trioxide aggregate|DRUG: Biodentine|BIOLOGICAL: Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myotonic Dystrophy Family Registry
Status: RECRUITING
Conditions: Myotonic Dystrophy|Congenital Myotonic Dystrophy|Myotonic Dystrophy 1|Myotonic Dystrophy 2|Dystrophia Myotonica|Dystrophia Myotonica 1|Dystrophia Myotonica 2|Myotonia Dystrophica|Myotonic Dystrophy, Congenital|Myotonic Myopathy, Proximal|PROMM (Proximal Myotonic Myopathy)|Proximal Myotonic Myopathy|Steinert Disease|Steinert Myotonic Dystrophy|Steinert's Disease|Myotonia Atrophica
Interventions: OTHER: Patient-entered data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Study to Determine Time to Steady-state
Status: COMPLETED
Conditions: Male Hypogonadism|Primary Hypogonadism|Secondary Hypogonadism
Interventions: DRUG: Testosterone undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empiric Versus Imaging Guided Left Ventricular Lead Placement in Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Imaging guided optimal LV lead placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of tDCS and tRNS in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Cognitive Impairment
Interventions: DEVICE: transcranial direct current stimulation (tDCS) active stimulator|DEVICE: transcranial random noise stimulation (tRNS)|DEVICE: transcranial direct current stimulation (tDCS) sham stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Imatinib Discontinuation in Chronic Myeloid Leukemia With Deep Molecular Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Chronic Myeloid
Interventions: DRUG: Pioglitazone 30 Mg Oral Tablet|OTHER: imatinib discontinuation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
Status: RECRUITING
Conditions: Anesthesia, Local|Ophthalmopathy|Strabismus|Pediatric ALL
Interventions: PROCEDURE: peribulbar block|PROCEDURE: sub-tenon block|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Yttrium-90 Ibritumomab Tiuxetan (Zevalin) With BEAM in Relapsed Low Grade B-Cell Lymphoma
Status: COMPLETED
Conditions: B-Cell Lymphoma
Interventions: DRUG: Zevalin plus BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes Using Collaborative Group Clinics to Empower Older Patients
Status: COMPLETED
Conditions: Diabetes|Hypertension
Interventions: BEHAVIORAL: Improving outcomes using group clinics for older patients|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis
Status: COMPLETED
Conditions: TTR-mediated Amyloidosis
Interventions: DRUG: Revusiran (ALN-TTRSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK/PD of High Dose Pip/Tazo in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Piperacillin/Tazobactam Standard Dose to High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase III Randomized, Double Blind, Placebo Controlled Multi-center Study of Panobinostat for Maintenance of Response in Patients With Hodgkin's Lymphoma (HL)
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Panobinostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine for Post-Tonsillectomy Pain in Pediatric Patients
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rice-richen and Wheaten-richen Meal on Glucose Control Among Chinese Women With Gestational Diabetes Melitus (GDM)
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: rice-richen meal|OTHER: wheaten-richen meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Gratitude Intervention on Stress Reactivity
Status: UNKNOWN
Conditions: Positive Emotions|Blood Pressure|Stress, Psychological
Interventions: BEHAVIORAL: Gratitude letter|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Egg White Supplementation in High-Intensity Functional Training
Status: COMPLETED
Conditions: Exercise Training|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Egg white|DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bacterial Cellulose-monolaurin Hydrogel for Acute Radiation Dermatitis
Status: UNKNOWN
Conditions: Acute Radiation Dermatitis
Interventions: OTHER: Bacterial cellulose-monolaurin hydrogel|OTHER: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a New Infant Formula With Specific Ingredients
Status: UNKNOWN
Conditions: Infant Growth
Interventions: DIETARY_SUPPLEMENT: Enriched infant formula|DIETARY_SUPPLEMENT: Standard formula|DIETARY_SUPPLEMENT: Breastfeeding arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Streptococcal Sepsis|Invasive Group A Beta-Haemolytic Streptococcal Disease|Necrotizing Soft Tissue Infection|Infection, Bloodstream|Infection, Bacterial|Streptococcal Toxic Shock Syndrome
Interventions: DRUG: Linezolid|DRUG: Clindamycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p