pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Onfi Conversion Therapy Replacing Clonazepam in Patients With Medically Refractory Epilepsy
Status: UNKNOWN
Conditions: Refractory Epilepsy
Interventions: DRUG: clobazam (Onfi)|DRUG: Initial conversion and titration|DRUG: Conversion schedule - Week 1|DRUG: Conversion schedule - Week 2|DRUG: Conversion schedule - Week 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: pregabalin sustained-release tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Influence of Injection Speed and Volume on the Perception of Subcutaneous Injection Pain
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: 0.9% NaCl (sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
Status: COMPLETED
Conditions: Baro-reflex Sensitivity|Heart Rate Variability|EEG, Microstates|Cerebral Blood Flow Regulation|Cerebral Oxygenation|Oxygen Saturation|Concentration Performance
Interventions: OTHER: Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Foundations in Developing Precision Cognitive Restoration
Status: WITHDRAWN
Conditions: Moderate Cognitive Impairment|Traumatic Brain Injury|Stroke
Interventions: DEVICE: intermittent Theta Burst Stimulation|DEVICE: Placebo intermittent Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stratified Evaluation of PDS and NACT-IDS in Ovarian Cancer (FOCUS)
Status: NOT_YET_RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Primary debulking surgery|PROCEDURE: Neoadjuvant chemotherapy|DRUG: PARPi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phaco-ECP vs Phaco Alone in Primary Angle Closure
Status: UNKNOWN
Conditions: Glaucoma, Angle-Closure
Interventions: PROCEDURE: Phacoemulsification|PROCEDURE: Endoscopic cyclophotocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC)
Status: UNKNOWN
Conditions: Bowel Preparation Solutions|Colonoscopy
Interventions: DRUG: 4L Klean Prep®|DRUG: 1L Klean prep® and 2 sachets Picoprep®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based vs Face-to-face Treatment for Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Dependence|Harmful Alcohol Use|Alcohol Use Disorder
Interventions: BEHAVIORAL: Guide to better alcohol habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The New Skin Stretching Device for Treatment of Limb Tension Wounds
Status: UNKNOWN
Conditions: Trauma|Fractures, Open|Wounds and Injuries|Skin Expander
Interventions: DEVICE: Skin stretching device (SSD)|PROCEDURE: Skin grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Decreases Visceral Fat Metabolism
Status: UNKNOWN
Conditions: To Evaluate the Effect of Pioglitazone on Glucose Metabolism of Fat Tissue by Using FDG-PET/CT Imaging
Interventions: DRUG: Pioglitazone vs Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma
Status: RECRUITING
Conditions: Glioma|IDH Mutation|Astrocytoma|Oligodendroglioma
Interventions: DRUG: Retifanlimab|DRUG: All-trans retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Tumor Grade 1|Neuroendocrine Tumor Grade 2
Interventions: DRUG: Lutetium Lu 177 dotatate therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Demonstrate the Efficacy and Safety of Internet-delivered Behavioral Treatment for Adults With Tic Disorders
Status: COMPLETED
Conditions: Tics|Tourette Syndrome
Interventions: BEHAVIORAL: (i)Comprehensive Behavioral Intervention for Tics|BEHAVIORAL: internet-delivered psychoeducation and relaxation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
Status: UNKNOWN
Conditions: Cryotherapy Effect|Burn Scar|Scar; Previous Cesarean Section
Interventions: DEVICE: Cold-air cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Single, Low-dose Dexamethasone in Patients After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Recoverben® on Recovery After Exhaustive Exercise
Status: COMPLETED
Conditions: Healthy Volunteers|Muscle Fatigue|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Aloysia citriodora extract|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Therapy for Intrauterine Adhesions Between Two Groups
Status: COMPLETED
Conditions: Asherman Syndrome
Interventions: DEVICE: Intrauterine balloon|DEVICE: Intrauterine Contraceptive Device Plus Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome
Status: COMPLETED
Conditions: Consciousness Disorders|Locked-In Syndrome
Interventions: DEVICE: mindBEAGLE EEG-based brain-computer interface
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Cocaine Use|Cocaine Dependence|Cocaine Use Disorder|Cocaine Use Disorder, Moderate|Cocaine Use Disorder, Severe
Interventions: DEVICE: Active H7-coil repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham H7-coil repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study of Auricular Acupressure for Postoperative Pain After Hemorrhoidectiomy
Status: UNKNOWN
Conditions: Postoperative Pain After Hemorrhoidectomy
Interventions: OTHER: IV-PCA|OTHER: IV-dezocine|OTHER: IV-PCA+AA|OTHER: IV-dezocine+AA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Reduce Loneliness in Elderly Patients in the Cardiac ICU (CICU)
Status: RECRUITING
Conditions: Loneliness
Interventions: BEHAVIORAL: Patient-tailored intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Status: COMPLETED
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men|Hot Flashes
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Placebo to elinzanetant|DRUG: Zopiclone|DRUG: Placebo to zopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Symbicort Versus Its Monocomponents - SPRUCE 160/4.5
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol|DRUG: budesonide|DRUG: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basic Body Awareness Therapy (BBAT) for Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Individual basic body awareness therapy|OTHER: Respiratory physiotherapy interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma|Metastatic Microsatellite Stable Colorectal Carcinoma|Refractory Colorectal Carcinoma|Stage IV Colorectal Cancer|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer|Stage IVC Colorectal Cancer|Colorectal Cancer Metastatic
Interventions: DRUG: Metformin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Merit WRAPSODY AV Access Efficacy Study (WAVE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Stenosis|Venous Occlusion
Interventions: DEVICE: Merit WRAPSODY Endovascular Stent Graft|DEVICE: PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Of CP-690,550 In Pediatric Patients With Juvenile Idiopathic Arthritis (JIA)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Operative Treatment of Olecranon Fractures
Status: UNKNOWN
Conditions: Olecranon Fracture
Interventions: PROCEDURE: Tension band wiring (TBW)|PROCEDURE: Plate fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Medication and Antidepressants for Treating Major Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: Triiodothyronine|OTHER: Placebo|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DCVAC/OvCa and Standard of Care (SoC) in Relapsed Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma
Status: WITHDRAWN
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Carcinoma
Interventions: BIOLOGICAL: DCVAC/OvCa|BIOLOGICAL: DCVAC/OvCa placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Obesity in Military Communities, Adolescents
Status: COMPLETED
Conditions: Obesity|Weight Gain|Disordered Eating|Eating Disorder
Interventions: BEHAVIORAL: Interpersonal Psychotherapy-Weight Gain|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study Investigating if Concomitant Injections of C-Tb and 2 T.U Tuberculin Affect Induration Responses
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: C-Tb|BIOLOGICAL: Tuberculin PPD RT 23 SSI|BIOLOGICAL: C-Tb / Tuberculin PPD RT 23 SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Milnacipran in Pediatric Patients With Primary Fibromyalgia
Status: TERMINATED
Conditions: Primary Fibromyalgia
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stories in the Moment: Dance Program for People Living With Dementia
Status: RECRUITING
Conditions: Dementia|Mild Cognitive Impairment|Alzheimer Disease|Lewy Body Disease|Frontotemporal Dementia|Vascular Dementia
Interventions: OTHER: Stories in the Moment Dance Program - Online
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Detection of Genetic Markers of Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: PROCEDURE: Biopsy of the major carinal area|PROCEDURE: Biopsy of abnormal & suspicious areas of the bronchial tree|PROCEDURE: Evaluation of the tumor for DNA mutations|PROCEDURE: Bronchoalveolar Lavage (BAL) for cytokine analysis|PROCEDURE: Correlation of flow cytometric & RT PCR for TNM stage|PROCEDURE: Analysis of lymph nodes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The MOTIVE (Multiparas Overcoming Childbirth Fear Through Intervention and Empowerement) Feasibility Trial
Status: COMPLETED
Conditions: Fear of Childbirth|Anxiety|Depression
Interventions: OTHER: An group intervention for multiparas with fear of childbirth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Evidence-Based Practice for Dizziness
Status: RECRUITING
Conditions: BPPV|Vestibular Diseases|Vertigo|Dizziness
Interventions: BEHAVIORAL: CME Educational Intervention|BEHAVIORAL: Study Developed Educational Materials for Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Cadazolid|DRUG: Vancomycin|DRUG: Placebo-matching cadazolid|DRUG: Placebo-matching vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Efficacy and Safety of HWH486 in Adults With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: HWH486|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib and Rituximab) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma
Status: RECRUITING
Conditions: Lymphoplasmacytic Lymphoma|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Ibrutinib|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tart Cherries and Melatonin Content
Status: COMPLETED
Conditions: Sleep
Interventions: DIETARY_SUPPLEMENT: Cherry juice|DIETARY_SUPPLEMENT: Fruit juice cordial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring the Effects of Therapeutic Education Program "Caratif" Patient Under Strong Opioids Versus Standard Taking Charge of Patient Pain Receiving Opioid Therapy in Medical Oncology.
Status: UNKNOWN
Conditions: Pain Management
Interventions: OTHER: therapeutic education of type "caratif|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Immunogenicity of 3+1 Versus 2+1 Schedule for PCV7
Status: COMPLETED
Conditions: Infectious Disease
Interventions: BIOLOGICAL: 7-valent pneumococcal conjugated vaccine|BIOLOGICAL: 7-valent pneumococcal conjugated vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Phase I Trial of Intravenous ASA404 Administered in Combination With Paclitaxel and Carboplatin in Japanese Patients With Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: ASA404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of the Structural Efficacy in Active RA Patients Treated With Sarilumab in Combination With MTX and Naive to Biologics
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Sarilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Taxol|DRUG: Fluorouracil|DRUG: Cytoxan|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Screening Phenotype Test To Evaluate CYP 2C19 Enzyme Activity Using Stable Isotope [13C]Pantoprazole
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [13C]Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Pomegranate Supplementation on Symptom Severity in Women With Premenstrual Syndrome
Status: COMPLETED
Conditions: Pomegranate|Premenstrual Syndrome
Interventions: DIETARY_SUPPLEMENT: pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of the EEG Signal Quality Measured by the URGOnight Device and Comparison With a Clinical Device
Status: COMPLETED
Conditions: Healthy Volonteers
Interventions: DEVICE: URGOnight|DEVICE: Enobio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Perception: Lidocaine Rate/Temp/Buffer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: PROCEDURE: Slow, Room Temperature Injection|PROCEDURE: Rapid, Room Temperature Injection|PROCEDURE: Slow, Warm Temperature Injection|PROCEDURE: Rapid, Warm Temperature Injection|PROCEDURE: Buffered Injection|PROCEDURE: Non-Buffered Injection|DRUG: Lidocaine|DRUG: Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Left Ventricular Pacing Vectors Effectiveness to Narrow Phrenic Nerve Stimulation
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy -Defibrillator (range PARADYM, LivaNova, Clamart, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Nab-Paclitaxel in High Risk Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: nab-Paclitaxel|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Major Depressive Disorder|Alzheimer's Dementia|Transcranial Direct Current Stimulation|tDCS
Interventions: OTHER: Receive tDCS+CR|OTHER: Facilitate tDCS + CR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1)
Status: COMPLETED
Conditions: Transcatheter Aortic Valve Replacement
Interventions: DRUG: Vitamin K antagonist or direct oral anticoagulant treatment|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Human Trial to Evaluate the Efficacy and Safety of Aged Garlic Powder on Improvement of Blood Lipids in Subjects With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Aged garlic powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Evaluation of Moxifloxacin in Vigadexa® in Aqueous Humor Samples Following Preoperative Antibiotic/Steroid Dosing in Cataract Surgery Patients
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Moxifloxacin 0.5%/Dexamethasone 0.1% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polyphenol Rich Supplementation on Markers of Recovery From Intense Resistance Exercise
Status: UNKNOWN
Conditions: Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Tart Cherry|OTHER: Placebo Oral Capsule [CEBOCAP]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
Status: SUSPENDED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: CBD Isolate|OTHER: CBD Broad Spectrum|OTHER: Placebo oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pregabalin for the Treatment of Acute Herpetic Neuralgia
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls
Status: COMPLETED
Conditions: Odontalgia
Interventions: DRUG: fentanyl|DRUG: S-ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy in Treating Older Women Who Are Undergoing Surgery for Stage I or Stage II Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adjustable Gastric Band Operations for Patients With Body Mass Index (BMI) Between 30-40 kg/m2
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: LAP-BAND® Adjustable Gastric Band (LAGB®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study
Status: UNKNOWN
Conditions: Glioma
Interventions: PROCEDURE: Detecting of Biological Borders of Gliomas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Sleep Apnea|Respiratory Tract Disease|Respiration Disorder
Interventions: DIAGNOSTIC_TEST: Sleepiz One Connect
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Value of Homeopathic Prophylaxis of Recurrent Urinary Tract Infections in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Symptomatic Urinary Tract Infection|Spinal Cord Injury
Interventions: OTHER: individual homeopathic treatment|OTHER: standard treatment without homeopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity|Tooth Erosion
Interventions: DEVICE: mouthguard|DEVICE: mouthguard with desensitizing toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Rosuvastatin in Healthy Male Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Rosuvastatin|DRUG: Fimasartan + Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Drowning Incidents in Danish Harbours
Status: NOT_YET_RECRUITING
Conditions: Drowning|Drown|Drowning; Anoxia|Drowning, Near|Drowning; Asphyxia|Drowning and Nonfatal Submersion|Drowning or Immersion of Unknown Intent|Drowning and Submersion, Undetermined Intent|Drowning and Submersion While in Natural Water|Drowning and Submersion Due to Sailboat Sinking|Drowning and Submersion Due to Fall Off Ship
Interventions: OTHER: Drowning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Percutaneous Ultrasonic Tenotomy Versus Platelet Rich Plasma for Gluteal Tendinopathy
Status: WITHDRAWN
Conditions: Gluteal Tendinitis|Trochanteric Bursitis|Tendinopathy
Interventions: DRUG: Leukocyte-Rich Platelet-Rich Plasma|PROCEDURE: Percutaneous Ultrasonic Tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Hematologic Malignancies|Graft vs Host Disease
Interventions: PROCEDURE: reduced intensity, related donor stem cell transplant|DRUG: tacrolimus (standard GVHD prophylaxis)|DRUG: mycophenolate (standard GVHD prophylaxis)|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MORphine Use in the Fascia Iliaca Compartment Block With UltraSound
Status: TERMINATED
Conditions: Humans|Anesthetics, Local|Morphine|Pain Management|Analgesia|Pain|Anesthesia, Local|Fascia|Emergency Medicine|Analgesia, Patient-Controlled|Ultrasonography|Femoral Fracture
Interventions: DRUG: Levobupivacaine|DRUG: Placebo|DRUG: Acetaminophen|DRUG: Morphine|PROCEDURE: Fascia Iliaca Compartment Block with Levobupivacaine|PROCEDURE: Fascia Iliaca Compartment Block with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Socket Preservation With Er:YAG and Nd:YAG Lasers
Status: COMPLETED
Conditions: Post-extraction Bone Regeneration
Interventions: DEVICE: Er:YAG and Nd:YAG lasers|PROCEDURE: Standard extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of CT-1500 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CT-1500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Breast Cancer|Colon Cancer|Pancreatic Cancer|Sarcoma|Ovarian Cancer
Interventions: BIOLOGICAL: p53: 264-272 peptide|DRUG: CT-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot RCT Comparing Effectiveness of Two Decision Aids for Hip and Knee Osteoarthritis
Status: COMPLETED
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: BEHAVIORAL: Brief interactive decision aid|BEHAVIORAL: Long video decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Of Different Types Of Physiotherapy Approaches In Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Exercise|OTHER: Low Level Laser Therapy|OTHER: Manuel Pressure Release|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of ALIMTA (Pemetrexed) Plus Irinotecan in Patients Who Have Been Previously Treated For Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: ALIMTA|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Different Doses of VAC52416 (ExPEC10V) in Japanese Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ExPEC10V|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Functional Exploration of Cartilage in Patients With Osteoarthritis of the Knee Through MRI Sodium ( 23Na )
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: OTHER: MRI Sodium ( 23Na )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Repeated, Escalating Doses of Intradermal Avotermin (Juvista)
Status: COMPLETED
Conditions: Cicatrix|Wound Healing
Interventions: DRUG: Avotermin|DRUG: Avotermin|DRUG: Avotermin|DRUG: Avotermin|DRUG: Avotermin|DRUG: Avotermin|DRUG: Placebo (vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study With Medical Nutrition Product PTM202 in Pediatric Diarrhea
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: OTHER: PTM202|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells
Status: TERMINATED
Conditions: Breast Carcinoma Metastatic in the Bone|Circulating Tumor Cell Count|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Positive|Stage IV Breast Cancer
Interventions: BIOLOGICAL: Denosumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Hybrid Effectiveness-Implementation Trial of Group CBT in Urban Schools
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: FRIENDS for Life|BEHAVIORAL: Adapted FRIENDS|BEHAVIORAL: Train-the-Trainer|BEHAVIORAL: Train-the-Trainer Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monovalent Chimpanzee Adenoviral-Vectored Sudan Ebolavirus Vaccine in Healthy Adults
Status: RECRUITING
Conditions: Ebola Sudan Virus Disease
Interventions: BIOLOGICAL: cAD3-Sudan Ebolavirus Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Placental Transfusion Methods and Stem Cells
Status: UNKNOWN
Conditions: Placental Transfusion|Stem Cells
Interventions: PROCEDURE: Delayed cord clamping|PROCEDURE: Umbilical cord milking|PROCEDURE: Immediate cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low FODMAPs Diet in Gastrointestinal Disorders
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Irritable Bowel Syndrome|Coeliac Disease
Interventions: DIETARY_SUPPLEMENT: low FODMAPs diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Constraint Induced Movement Therapy (CIMT) in Babies Home Program
Status: UNKNOWN
Conditions: Hemiplegia|Cerebral Palsy
Interventions: DEVICE: Constraint induced movement therapy (CIMT)|BEHAVIORAL: play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Anesthesia,Spinal|Postoperative Nausea and Vomiting
Interventions: DRUG: Bupivacaine|DRUG: Morphine|DRUG: Isotonic saline solution|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Seladelpar in Subjects With Hepatic Impairment and Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: seladelpar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic|Systemic Vasculitis|Isolated Angiitis of Central Nervous System|Lung Disease With Systemic Sclerosis|Lung Disease Interstitial Diffuse
Interventions: DRUG: depot leuprolide acetate 3.75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Clinical Characteristics ,Risk Factors and Outcome of Lupus Nephritis Among Children With Systemic Lupus Erthromatousus in Sohag Univeristy Hospital
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DIAGNOSTIC_TEST: renal biobsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5
Status: TERMINATED
Conditions: Chronic Kidney Disease (CKD) Stage 5|Hypertrophy, Left Ventricular
Interventions: DRUG: paricalcitol injection 4 mcg/mL|DRUG: Placebo Injection 4 mcg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Blood Clots in Patients Undergoing Chemotherapy for Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Gastric Cancer|Lung Cancer|Ovarian Cancer|Pancreatic Cancer|Prostate Cancer|Thromboembolism
Interventions: OTHER: clinical observation|PROCEDURE: management of therapy complications|PROCEDURE: ultrasound imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Optimal Posology of Gonadotrophins in Patients With Insufficient Ovarian Response Due to Age
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: Gonal-f®: follitropin alpha|DRUG: Gonal-f®: follitropin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Critical Pathway for Implantable Cardioverter-Defibrillators in Patients With Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Myocardial Infarction|Heart Failure
Interventions: OTHER: Use of the ICD Critical Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Totum-63 on Glucose and Lipid Homeostasis in Subjects With Dysglycemia (REVERSE-IT)
Status: COMPLETED
Conditions: Prediabetic State|Diabetes type2|Dysglycemia
Interventions: DIETARY_SUPPLEMENT: TOTUM-63 3 intakes per day|DIETARY_SUPPLEMENT: Placebo 3 intakes per day|DIETARY_SUPPLEMENT: TOTUM-63 2 intakes per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NEOadjuvant Gemcitabine/Oxaliplatin Plus Adjuvant Gemcitabine in Resectable PAncreatic Cancer
Status: COMPLETED
Conditions: Pancreas Cancer
Interventions: DRUG: Neoadjuvant chemotherapy|PROCEDURE: surgery and Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Incentive Spirometery on Asthmatic Pregnant Women
Status: COMPLETED
Conditions: Asthmatic|Pregnant With Complication
Interventions: DRUG: pulmicort inhaler|DEVICE: Incentive spirometer treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilator-driven Alveolar Recruitment Maneuver
Status: COMPLETED
Conditions: Postoperative Atelectasis|Ventilator Lung|Atelectasis|Recruitment
Interventions: OTHER: Alveolar recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Progesterone Versus Placebo for the Treatment of Vaginal Atrophy
Status: WITHDRAWN
Conditions: Atrophic Vaginitis|Menopause|Vulvovaginal Atrophy
Interventions: DRUG: Vaginal progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Positron Emission Tomography Study in Healthy Male Subjects to Investigate Brain DAT and SERT Occupancy,Pharmacokinetics and Safety of Single Oral Doses of GSK1360707, Using 11C- PE2I and 11C-DASB as PET Ligands
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: GSK1360707 is a potent re-uptake inhibitor of the neurotransmitters dopamine, norepinephrine and serotonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Choline Alphoscerate for Older Adults With Major Depression and Subjective Memory Complaints
Status: NOT_YET_RECRUITING
Conditions: Major Depression
Interventions: DRUG: choline alphoscerate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training on Diaphragm Thickness, Respiratory Muscle Strength and Balance in Dancers.
Status: UNKNOWN
Conditions: Athletic Injuries
Interventions: OTHER: Inspiratory muscle training(high-IMT group)|OTHER: Inspiratory muscle training(low-IMT group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: M7824|DRUG: Placebo|DRUG: Durvalumab|DRUG: Etoposide|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Smoking on Saliva Composition and the Development of Dental Erosion
Status: COMPLETED
Conditions: Dental Erosion
Interventions: OTHER: Use of fluoridated toothpaste|OTHER: Wearing of an intraoral device with bovine tooth samples|OTHER: Wearing of an intraoral device with resin samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EndoChoice's Fuse® Endoscopic System Performance In Routine Practice
Status: COMPLETED
Conditions: Miscellaneous Gastroenterology and Urology Devices Associated With Adverse Incidents, Not Elsewhere Classified
Interventions: DEVICE: Fuse® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RCT Comparing Tailored Versus Targeted Organ Donation Video Education
Status: COMPLETED
Conditions: Organ Transplants
Interventions: BEHAVIORAL: Control Group|BEHAVIORAL: Targeted Intervention|BEHAVIORAL: Tailored Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation
Status: COMPLETED
Conditions: Postoperative Wound Infection
Interventions: OTHER: Plain soap and water (PSW)|OTHER: Alcohol-based hand rub (ABHR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Glofitamab as Single Agent Administered After Pretreatment With Obinutuzumab in Chinese Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Glofitamab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sanofi Pasteur, TIV + H1N1, Pediatric Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated H1N1 Vaccine|BIOLOGICAL: Trivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of Oral Misoprostol Alone Versus Oral Misoprostol Followed by Oxytocin for Labour Induction
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DRUG: Oral misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Occurence of Pancreatic Cancer Studied in Association With Newly Diagnosed Diabetes in the Elderly
Status: RECRUITING
Conditions: Diabetes Mellitus|Diabetes|Diabetes Mellitus, Type 2|Diabetes type2|Cancer of Pancreas|Pancreas Neoplasm|Pancreas Adenocarcinoma|Pancreatic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Effects of Active Release Technique and Post Isometric Relaxation on Adductor Strain in Mixed Martial Arts Fighters
Status: RECRUITING
Conditions: Adductor Strain
Interventions: PROCEDURE: Cryotherapy|PROCEDURE: Strengthening of adductors|PROCEDURE: Active release technique|PROCEDURE: Post-Isometric Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT