pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyponatremia
Interventions: OTHER: Targeted correction of plasma sodium levels|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Irrigation for Pancreatoduodenectomy
Status: COMPLETED
Conditions: Surgery|Infection
Interventions: DRUG: Polymyxin B in Normal Saline|OTHER: Placebo: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Drug: Selumetinib|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left vs Right Radial Approach in the Setting of Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction
Status: COMPLETED
Conditions: Transradial Approach, Primary PCI, ST-segment Elevation Myocardial Infarction
Interventions: PROCEDURE: Left radial approach|PROCEDURE: Right radial approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UVB Phototherapy Treatment of Oral Chronic GVHD
Status: TERMINATED
Conditions: Oral Chronic Graft-Versus-Host Disease
Interventions: PROCEDURE: Narrow-Band UVB Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined S-1 With DC+CIK As Maintenance Therapy For Advanced Pancreatic Ductal Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Advanced Solid Tumor
Interventions: BIOLOGICAL: Dendritic cell + Cytokine-induced killer cell (DC+CIK) immunotherapy|DRUG: Tegafur Only Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Endovascular Thrombectomy|OTHER: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease
Status: ENROLLING_BY_INVITATION
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Pravastatin|DRUG: sodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Sensitivity
Interventions: PROCEDURE: In-office Dental Bleaching Conventional|PROCEDURE: In-office Dental Bleaching Alternative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Memory Enriched T Cells Following Stem Cell Transplant in Treating Patients With Recurrent B-Cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Mantle Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Mantle Cell Lymphoma|Transformed Recurrent Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells|BIOLOGICAL: Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CVT-SFA First in Human Trial for Treatment of Superficial Femoral Artery or Proximal Popliteal Artery
Status: ACTIVE_NOT_RECRUITING
Conditions: Femoral Artery Stenosis|Popliteal Artery Stenosis|Femoral Artery Occlusion|Popliteal Artery Occlusion
Interventions: DEVICE: Peripheral PTA with a drug coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamic Effect of Different Concentrations of a New Anti-inflammatory Substance in Subjects With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 134310|DRUG: LEO 134310|DRUG: LEO 134310|DRUG: LEO 134310|DRUG: LEO 134310 vehicle|DRUG: 0.1% betamethasone valerate ointment (class III steroid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation
Status: TERMINATED
Conditions: Adenovirus Infection
Interventions: DRUG: Posoleucel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)
Status: UNKNOWN
Conditions: Obesity|Chronic Inflammation
Interventions: DIETARY_SUPPLEMENT: Dietary plan along with fish oil capsules (3 capsules daily. Containing EPA+DHA: 1.8 g).|DIETARY_SUPPLEMENT: Dietary plan along with chia/linseed oil capsules (3 capsules daily. Containing ALA 1.6 g).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Laboratory Study of MK0928 in Adult Patients With Primary Insomnia (0928-041)(TERMINATED)
Status: TERMINATED
Conditions: Primary Insomnia
Interventions: DRUG: MK0928, gaboxadol / Duration of Treatment: 6 days for treatment periods (2 days/dose)|DRUG: Placebo / Duration of Treatment: 2 days for screening period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sitagliptin on Progression of Coronary Intermediate Lesion
Status: COMPLETED
Conditions: Atherosclerosis|Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of SP2086 to Treat Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo|DRUG: 50 mg SP2086|DRUG: 100 mg SP2086|DRUG: 200 mg SP2086|DRUG: 100 mg Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8|Metastatic Breast Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Neoplasm in the Liver|Metastatic Malignant Neoplasm in the Lung|Metastatic Malignant Neoplasm in the Lymph Nodes|Metastatic Malignant Neoplasm in the Spine|Prognostic Stage IV Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8
Interventions: RADIATION: Stereotactic Body Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Metabolism and Pharmacokinetics of Ambroxol in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-cyclohexane ambroxol oral solution|DRUG: [14C]-benzyl ambroxol oral solution|DRUG: Ambroxol lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases, Adult|Neurocognitive Function|Cancer
Interventions: RADIATION: Cognitive Sparing Brain Stereotactic Radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia of TAP Block for Laparoscopic Sleeve Gastrectomy
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: OTHER: subcostal TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: liraglutide|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars
Status: UNKNOWN
Conditions: Acne Scars
Interventions: DRUG: 70% glycolic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Multicentre Clinical Study to Evaluate the Usability and Safety of the Autoinjector and Pre-filled Syringe of SB4 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DEVICE: Autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 2 Open-label Single-arm Trial of JAK1 Inhibitor for the Treatment of Large Inflammatory Hepatocellular Adenomas
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Hepatocellular Adenoma
Interventions: DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nutritional Intervention for Diabetic Neuropathy (WCCR-DN2)
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: OTHER: Vegan diet and vitamin B12 supplement|DIETARY_SUPPLEMENT: Vitamin B12 supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7249 Injection in Healthy Subjects
Status: RECRUITING
Conditions: Hyperlipidemia
Interventions: DRUG: HRS-7249 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome
Status: RECRUITING
Conditions: Childhood Idiopathic Nephrotic Syndrome
Interventions: DRUG: Obinutuzumab|DRUG: MMF|DRUG: Prednisone|DRUG: Methylprednisolone|DRUG: Acetaminophen/ Paracetamol|DRUG: Diphenhydramine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carriage of Streptococcus Pneumoniae in Infants With Acute Otitis Media and in Infants Attending Day-care Centers
Status: COMPLETED
Conditions: Streptococcus Pneumoniae|Nasopharyngeal Carriage
Interventions: OTHER: Nasopharyngeal sampling with a swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Substitution of the PCL in TKA With UC or PS Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Patient Reported Outcome|Knee Osteoarthritis|Knee Arthroplasty
Interventions: OTHER: TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Supplements With Fish Oil on Mannitol-induced Airway Sensitivity & Inflammation in Persons With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: omega-3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The BALANCED Anaesthesia Study
Status: WITHDRAWN
Conditions: Effect of General Anesthetic Dose on Recovery From Surgery
Interventions: PROCEDURE: Light general anaesthesia (BIS = 50)|PROCEDURE: deep general anaesthesia (BIS = 35)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: sorafenib tosylate|DRUG: tipifarnib|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid in the Treatment of Periodontal Pockets
Status: COMPLETED
Conditions: Chronic Periodontitis With Infra-bony Defects
Interventions: DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of HBI-8000 (Tucidinostat) With Pembrolizumab in Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: HBI-8000 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and Flu
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Nasal Congestion|Rhinorrhea|Sneezing
Interventions: DRUG: Paracetamol (500 mg)/dimethindene maleate (1 mg)/ phenylephrine hydrochloride (10 mg) tablets|DRUG: Paracetamol (500 mg) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Escalating Oral Vitamin D Replacement on HOMA-IR in Vitamin D Deficient Type 2 Diabetics
Status: COMPLETED
Conditions: Vitamin D Deficiency|Insulin Resistance|Diabetes Mellitus, Type 2
Interventions: DRUG: oral vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Mechanisms of Stress in Youth With Chronic Widespread Pain
Status: RECRUITING
Conditions: Chronic Widespread Pain|Stress, Psychological|Stress, Physiological
Interventions: DIAGNOSTIC_TEST: functional Magnetic Resonance Imaging (fMRI)|OTHER: Allostatic Load Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auger Molecular Therapy (AMT) for Malignant Cutaneous Lesions Treatment
Status: RECRUITING
Conditions: Malignant Fungating Wound
Interventions: COMBINATION_PRODUCT: Auger Molecular Therapy (AMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Aliskiren in Pediatric Hypertensive Patients 6-17 Years of Age
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren (6.25/12.5/25 mg)|DRUG: Aliskiren (37.5/75/150 mg)|DRUG: Aliskiren (150/300/600 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Plitidepsin (Aplidin®) in Combination With Bortezomib and Dexamethasone in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Plitidepsin|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Camrelizumab(SHR-1210) Combined With Apatinib in the Treatment of Advanced Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial)
Status: COMPLETED
Conditions: Ventral Hernia Repair
Interventions: DRUG: Gemcitabine/ clindamycin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Radiation and Veliparib for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Radiation|PROCEDURE: Lumpectomy/Mastectomy|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Assessing Efficacy of an Herbal Blend on Menopausal Symptoms and Quality of Life
Status: UNKNOWN
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: phytoestrogen herbal blend|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iTBS rTMS in Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: iTBS rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1- Antihistamines
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: LOU064 (blinded)|DRUG: Placebo|DRUG: LOU064 (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Platelet Function Test in Prevention of Ischemic Events After Stent Placement in Intracranial Aneurysms
Status: COMPLETED
Conditions: Unruptured Intracranial Aneurysm|Stents|Antiplatelet Drugs
Interventions: DRUG: Aspirin and clopidogrel/Ticagrelor|DEVICE: Light transmittance aggregometry|DRUG: Aspirin and clopidogrel/Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Roxadustat Conversion in Participants Receiving Stable ESA or as Initial Anemia Treatment in Hemodialysis Participants
Status: COMPLETED
Conditions: Anemia Associated With End Stage Renal Disease
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery With Epidural Anesthesia or Spinal Anesthesia Without Intubation
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Dexmedetomidine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative and Antioxidant Indices to HIIT and Aloe Vera Supplementation in Patients With T2DM
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: Exercise|DIETARY_SUPPLEMENT: Aloe vera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VALES+Tú: Targeting Psychosocial Stressors to Reduce Latino Day Laborers (LDL) Injury Disparities
Status: COMPLETED
Conditions: Work-related Injury
Interventions: BEHAVIORAL: individual -Brief Motivational Intervention (BMI)|BEHAVIORAL: Group (Group Problem Solving)|BEHAVIORAL: Standard of Care (OSHA 10 Safety Cards)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Schemes of Administration of Intravenous Ketamine in Depression
Status: UNKNOWN
Conditions: Treatment Resistant Depression
Interventions: DRUG: Ketamine 50 MG/ML Injectable Solution, 0.5 mg/kg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Absorption Comparison on Equivalency Value of Genepro Gen2
Status: COMPLETED
Conditions: Analysis, Event History|Absorption; Disorder, Protein
Interventions: DIETARY_SUPPLEMENT: Genepro Protein|DIETARY_SUPPLEMENT: Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section
Status: COMPLETED
Conditions: Anesthesia, Spinal
Interventions: DRUG: Dexmedetomidine & Bupivacaine.|DRUG: Bupivacaine Only.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand
Status: COMPLETED
Conditions: HIV Infections|Chlamydia Trachomatis|Nesseria Gonorrhea|Trichomonas Vaginitis|Syphilis
Interventions: DRUG: Carraguard (PC-515)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: gemcitabine hydrochloride|PROCEDURE: quality-of-life assessment|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Arterial Denervation in Sympathetic Dysautonomia
Status: RECRUITING
Conditions: Hypertension|Renal Denervation|Increased Variability|Blood Pressure Disorders|Blood Pressure Variability|Sympathetic Dysautonomia
Interventions: DEVICE: Renal denervation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BAY38-9456 (Vardenafil HCL Tablet) in ED Treatment for China Registration.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity
Status: COMPLETED
Conditions: Retinopathy of Prematurity (ROP)
Interventions: BIOLOGICAL: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Differences Between Left Arm and Right Arm Using a Continuous Glucose Monitor
Status: UNKNOWN
Conditions: Diabetes
Interventions: OTHER: Intermittent Fasting|OTHER: Free-Living Diet|OTHER: Left Arm Exercise|OTHER: Right Arm Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment
Status: COMPLETED
Conditions: Multiple Sclerosis|Walking Impairment
Interventions: DRUG: ADS-5102, 274 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration
Status: COMPLETED
Conditions: HIV Infections|AIDS|Opiate Dependence|Post-Traumatic Stress Disorders
Interventions: DRUG: On-site - buprenorphine/naloxone (Suboxone)|DRUG: Off-site - methadone or no agonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Buprenorphine to Improve HIV Care Engagement and Outcomes
Status: COMPLETED
Conditions: HIV|Substance Related Disorders
Interventions: DRUG: Buprenorphine/naloxone|DRUG: Methadone Maintenance Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HR+/HER2- Metastatic Breast Cancer Patients Treated With Palbociclib Together With an Aromatase Inhibitor From 2017 to 2023 in Denmark.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib in combination with AI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine and Influenza Combination Vaccine
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: CIC Vaccine Co-formulated tNIV2 , SARSCoV-2 rS and Matrix-M Adjuvant|BIOLOGICAL: Novavax COVID-19 Vaccine|BIOLOGICAL: Comparator Influenza Vaccine - Fluarix|BIOLOGICAL: Comparator Influenza Vaccine -Fluarix High Dose|BIOLOGICAL: Placebo 0.9% sodium chloride for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pain Expectations in Subjects With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Modafinil|DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Polyethylene Glycols|DRUG: Natrium picosulfate / Magnesium citrate|DRUG: Polyethylene glycol / Ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Spine Manipulation for Individuals With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Manipulation|OTHER: Sham Manipulation|OTHER: Core Strengthening Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DSA Intragraft in Lung Transplantation: Diagnostic and Prognostic Value in Antibody Mediated Rejection
Status: RECRUITING
Conditions: Lung Transplant Recipient|Donor Specific Antibodies|Antibody Mediated Rejection
Interventions: PROCEDURE: bronchoscopy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot Initiative
Status: COMPLETED
Conditions: Invasive Breast Carcinoma|Triple-Negative Breast Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequencing Abiraterone and Enzalutamide in mCRPC
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ConsCIOUS2 Study of the Isolated Forearm Technique Commands
Status: COMPLETED
Conditions: Anesthesia Awareness
Interventions: OTHER: IFT Testing1|OTHER: IFT Testing 2|OTHER: IFT Testing 3|OTHER: IFT Testing 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Chronic Eosinophilic Leukemia, Not Otherwise Specified|Chronic Myelomonocytic Leukemia|Chronic Neutrophilic Leukemia|Essential Thrombocythemia|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Myeloid Neoplasm|Myeloproliferative Neoplasm|Myeloproliferative Neoplasm, Unclassifiable|Overt Primary Myelofibrosis|Polycythemia Vera|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase|Prefibrotic/Early Primary Myelofibrosis
Interventions: DRUG: Azacitidine|DRUG: Pevonedistat|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: Experimental: endovascular thrombectomy in patients who suffer a distal medium vessel occlusion|OTHER: Standard medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of the SoundBite™ Crossing System in Complex Peripheral CTOs
Status: WITHDRAWN
Conditions: Peripheral Arterial Occlusive Disease|Chronic Total Occlusion of Artery of the Extremities
Interventions: DEVICE: SoundBite™ Crossing System - Peripheral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Test the Effect of Selected Fibres and Flours in Flat Bread on Post-Prandial Blood Glucose and Insulin Responses in Healthy Indian Population
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Control (market standard)|OTHER: wheat flour|OTHER: chickpea flour|OTHER: guar gum|OTHER: barley
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of Preservative-free Polyhexamethylene Biguanide (PHMB) Ophthalmic Solution in Healthy Subjects
Status: COMPLETED
Conditions: Acanthamoeba Keratitis
Interventions: DRUG: 0.04% PHMB|DRUG: 0.06% PHMB|DRUG: 0.08% PHMB|DRUG: PHMB Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3090106 in Healthy Participants and Participants With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: LY3090106 - SQ|BIOLOGICAL: LY3090106 - IV|BIOLOGICAL: Placebo - SQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integrating U=U Into HIV Counseling in South Africa
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Tablet based U=U app|BEHAVIORAL: U=U videos played in clinic waiting rooms and integrated into HIV counseling session|OTHER: Text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Scapula Retraction Exercises in Subacromial Pain Syndrome
Status: COMPLETED
Conditions: Rotator Cuff Impingement Syndrome
Interventions: OTHER: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a New Medical Device in Gel Formulation Versus Calgel® for the Topical Treatment of Teething in Infants
Status: COMPLETED
Conditions: Pain Teeth
Interventions: DEVICE: Hyaluronic Acid 0.54%|DRUG: Calgel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norovirus Bivalent-Vaccine Efficacy Study
Status: COMPLETED
Conditions: Prevention From Norovirus Infection
Interventions: BIOLOGICAL: Norovirus Bivalent Vaccine|BIOLOGICAL: Saline Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Secondary-progressive Multiple Sclerosis
Interventions: DRUG: Mayzent|DRUG: Ocrevus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: FDG PET/CT in Monitoring Very Early Therapy Response in Patients With Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Family Financial Support on Parental Mental Health
Status: COMPLETED
Conditions: Financial Coaching|Mental Disorders|Social Determinants|Medical-Financial Partnership|Toxic Stress
Interventions: BEHAVIORAL: Financial Coaching|BEHAVIORAL: Access to Social Service Referrals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: INDICOR The Paclitaxel-Eluting PTCA-Balloon Catheter in Combination With a Cobalt-Chromium Stent
Status: COMPLETED
Conditions: Coronary Heart Diseases
Interventions: DEVICE: Drug Eluting Balloon SeQuent Please|DEVICE: Drug Eluting Balloon SeQuent Please
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery
Status: RECRUITING
Conditions: Mortality|Postoperative Complications
Interventions: DRUG: reducing anticholinergic burden
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Fractional Booster Dose of IPV Intradermally Versus Full Dose Intramuscularly
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Inactivated types 1, 2, and 3 poliovirus, D antigens|BIOLOGICAL: Inactivated types 1, 2, and 3 poliovirus, D antigens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diclofenac Plus Lidocaine Gel for Pain Relief During Intrauterine Device Insertion(IUD).
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac plus lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Secondary Debulking Surgery +/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Secondary debulking|PROCEDURE: secondary debulking with intraperitoneal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid in Postoperative Cures in the Phenol/Alcohol Technique
Status: COMPLETED
Conditions: Nails, Ingrown|Hyaluronic Acid
Interventions: DRUG: Hialucic|DRUG: Betadine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Marginal Integrity Using Bioactive Cement Incementation of Indirect Composite Blocks
Status: UNKNOWN
Conditions: Resin Cement
Interventions: DRUG: Active bio Activa|DRUG: Resin Cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial
Status: RECRUITING
Conditions: Epigenetic Aging|Immunosenescence
Interventions: COMBINATION_PRODUCT: TRIIM Treatment|COMBINATION_PRODUCT: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinematic and Kinetic Effects of Orthotic Devices for Subjects With Stage II Posterior Tibial Tendon Dysfunction
Status: UNKNOWN
Conditions: Posterior Tibial Tendon Dysfunction
Interventions: DEVICE: Arizona
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: Pegloticase|DRUG: Methotrexate (MTX)|DRUG: Standard Gout Flare Prophylaxis|DRUG: Infusion Reaction (IR) Prophylaxis|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
Status: COMPLETED
Conditions: Necrotizing Soft Tissue Infections|Necrotizing Fasciitis|Fournier's Gangrene
Interventions: DRUG: AB103 0.5 mg/kg|OTHER: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Negative Pressure Wound Therapy (VAC) in Gynecologic Oncology (G.O.)
Status: UNKNOWN
Conditions: Wound Infection|Gynecologic Cancer
Interventions: DEVICE: VAC therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: LY2603618|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Exercise Combined With Ketone Ester Supplement
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity|Cognitive Change|Ketoses, Metabolic
Interventions: OTHER: Ketone monoester supplementation|OTHER: High-intensity interval exercise|OTHER: Moderate-intensity continuous exercise|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of US-Guided PCNL Different Positions in Renal Stones Treatment
Status: COMPLETED
Conditions: Percutaneous Nephrolithotomy|Renal Stones|Ultrasound Therapy; Complications
Interventions: PROCEDURE: Flank suspended supine position percutaneous nephrolithotomy|PROCEDURE: Supine percutaneous nephrolithotomy group|PROCEDURE: Prone percutaneous nephrolithotomy group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Equivalence of the Response to Vaccination of Tacrolimus Ointment to a Steroid Ointment Regimen in Children With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: tacrolimus ointment 0.03%|DRUG: hydrocortisone acetate ointment 1%|DRUG: hydrocortisone butyrate ointment 0.1%|BIOLOGICAL: Meningitec|BIOLOGICAL: AC VAX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Status: COMPLETED
Conditions: Malignancies|Acute Lymphoblastic Leukemia (ALL)|Acute Myeloid Leukemia (AML)|Non-Hodgkin's Lymphoma|Neuroblastoma
Interventions: DRUG: chemotherapy|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride, Cisplatin, and AGS-003-BLD in Treating Patients With Muscle-Invasive Bladder Cancer Undergoing Surgery
Status: WITHDRAWN
Conditions: Infiltrating Bladder Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma|Stage III Bladder Urothelial Carcinoma|Stage IV Bladder Urothelial Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Radical Cystectomy|BIOLOGICAL: Tumor Cell-Derived Vaccine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients
Status: UNKNOWN
Conditions: Nutrition Disorders|Neurologic Disorder
Interventions: OTHER: whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anal Crohn Fistula Surgery
Status: UNKNOWN
Conditions: Crohn Disease|Fistula|Anoperineal Fistula|Anal Fistula
Interventions: PROCEDURE: All types of surgery procedures|PROCEDURE: Simple seton drain removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADIPOA - Clinical Study
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Autologous adipose derived stem cells administrated for intra-articular use|BIOLOGICAL: Autologous adipose derived stem cells administrated for intra-articular use
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
Status: UNKNOWN
Conditions: Gastrointestinal Neoplasms|Abnormality of Enteric Nervous System Morphology
Interventions: DRUG: Sodium thiosulfate and Methylene blue solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Assessment of the Safety and Efficacy of the Minnow Medical GRST™ Peripheral Catheter System
Status: TERMINATED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: GRST Peripheral Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Metabolism and Pharmacokinetics of [14C]BI 1744 CL and [14C]BI 1744 CL Administered as an Oral Solution in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1744 CL i.v.|DRUG: BI 1744 CL oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Motor Intervention for Preterm Babies
Status: COMPLETED
Conditions: Preterm Babies
Interventions: OTHER: Breast milk-scented PIOMI|OTHER: Breast milk-tasting PIOMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: (YMP) Young Moms Program
Status: COMPLETED
Conditions: Chronic Toxic Stress|Developmental/ Behavioral Regression in Young Children
Interventions: BEHAVIORAL: "traditional" Parents as Teachers (PAT)|BEHAVIORAL: "hybrid" PAT model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Split-face Comparison Study to Assess ELAPR Compared to Juvéderm® for the Treatment of Nasolabial Folds
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Juvéderm® Ultra Plus|DEVICE: ELAPR002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT