pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Laboratory Characteristics in Chronic Atrophic Acrodermatitis
Status: UNKNOWN
Conditions: Chronic Atrophic Acrodermatitis
Interventions: DRUG: doxycycline orally, 100 mg, bid, 14 days|DRUG: doxycycline orally, 100 mg, bid, 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Infusion System for Hepatic Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic to Liver|Intrahepatic Cholangiocarcinoma
Interventions: DEVICE: Medtronic SynchroMed II programmable pump connected to an Intera tapered catheter (Combined Infusion System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of a Once Daily Dose of 50 mg E2609 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: E2609|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Tracheostomy Tube That Enables Communication
Status: COMPLETED
Conditions: Evaluate the Effect of a Talking Tracheostomy Tube on Quality of Life
Interventions: DEVICE: Portex Blueline Ultra Suctionaid Tracheostomy Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Protein Supplementation on Postoperative Complications in Elderly Sarcopenic Cancerous Patients
Status: TERMINATED
Conditions: Sarcopenia|Cancer
Interventions: DIETARY_SUPPLEMENT: enteral nutrition supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of i.v Oxycodone for Postoperative Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oxycodone, 1.00 mg dose|DRUG: Oxycodone, 0.03 mg/kg dose|DRUG: Oxycodone, 0.02 mg/kg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis
Status: TERMINATED
Conditions: Opioid-use Disorder|Opioid Use|Opioid Dependence|Opioid Abuse|Medication Assisted Treatment|Infusion Catheter, Wound|Lidopatch|Ambu ACTion|Pregnancy Related|Cesarean Section
Interventions: DRUG: Lidocaine patch|DEVICE: Ambu ACTion pump, 0.125% bupivacaine at 8cc/hr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone & SSRI in Alcoholics With Depression/PTSD
Status: COMPLETED
Conditions: Alcoholism|Depression|PTSD
Interventions: DRUG: paroxetine|DRUG: desipramine|DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan in Respiratory Failure Due to COVID-19
Status: COMPLETED
Conditions: COVID-19|Respiratory Insufficiency|Telmisartan|Respiratory Distress Syndrome, Adult
Interventions: DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic MRI Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Leiomyomas
Interventions: DEVICE: Philips MR-guided HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DEVICE: 1Hz TMS with H2 coil|DEVICE: 10Hz TMS with H2 coil to prefrontal and parieto-temporal cortex|DEVICE: SHAM TMS with H2 coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Albuterol Sulfate|DRUG: Interferon gamma-primed mesenchymal stromal cells (MSCs)|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing a Regorafenib-irinotecan Combination Versus Regorafenib Alone in Metastatic Colorectal Cancer Patients
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer (mCRC)
Interventions: DRUG: Regorafenib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Status: COMPLETED
Conditions: Neurogenic Orthostatic Hypotension|Non-Diabetic Autonomic Neuropathy|Multiple System Atrophy|Dopamine Beta Hydroxylase Deficiency
Interventions: DRUG: Droxidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate Safety, Pharmacokinetics, Immunogenicity and Pharmacodynamics/Efficacy of EDI200 in Male Infants With X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)
Status: COMPLETED
Conditions: X-Linked Hypohidrotic Ectodermal Dysplasia
Interventions: DRUG: EDI200
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of NEOIAL HC for Intra-articular Use in the Treatment of Severe Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: Neoial HC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Assessment of Gonal f Solution for Injection in a Prefilled Pen for Follicular Stimulation in in Vitro Fertilisation/Embryo Transfer (IVF-ET) Cycles
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Quality of Life Questionnaire (FertiQoL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Status: RECRUITING
Conditions: Anxiety|Depression|Internalizing Problems|Low Mood
Interventions: BEHAVIORAL: CBT-informed school-based counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a for Safety, PK and PD of SQY51 in Paediatric and Adult Patients Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Phase 1, SQY51|DRUG: Phase 2a, SQY51 (cohort 1)|DRUG: Phase 2a, SQY51 (cohort 2)|DRUG: Phase 2a, SQY51 (cohort 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of MAX-002 Suppository Versus Placebo and Active Medicine in Mild to Moderate Ulcerative Proctitis
Status: TERMINATED
Conditions: Proctitis, Ulcerative
Interventions: DRUG: MAX-002|DRUG: Placebo|DRUG: Canasa®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Early CABG (Day 2-3 after ticagrelor discontinuation)|PROCEDURE: Delayed CABG (Day 5-7 after ticagrelor discontinuation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microparticle Enhanced Cytotoxic Transarterial Embolization Therapy
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DEVICE: 40um Embozene TANDEM Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pin and Vacuum Assisted Suspension Systems
Status: COMPLETED
Conditions: Amputees|Prosthesis User|Artificial Limbs
Interventions: OTHER: Pin Suspension System (a prosthetic suspension system)|OTHER: Vacuum-Assisted Suspension System (a prosthetic suspension system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Medication Adherence in Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: OTHER: Disease activity in psoriatic arthritis (DAPSA)|OTHER: Compliance-Questionnaire-Rheumatology (CQR)|OTHER: The Brief Illness Perception Questionnaire (BIPQ)|OTHER: The Beliefs About Medicines Questionnaire (BMQ)|OTHER: Hospital Anxiety and Depression Scale (HADS)|OTHER: The Psoriatic Arthritis Quality of Life (PsAQoL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tripterygium Wilfordii Hook F and Methotrexate for Postmenopausal Women With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tripterygium wilfordii Hook F (TwHF)|DRUG: Methotrexate|OTHER: Dummy Tripterygium wilfordii Hook F (TwHF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Velcade and Irinotecan in Advanced Cervical, Vulvar, or Vaginal Cancer
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: DRUG: Velcade (bortezomib)|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Cat-PAD Study
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: DRUG: Cat-PAD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiotensin-(1-7) in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: therapeutic angiotensin-(1-7)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yang Yin Fu Zheng Jie Du Therapy in Recurrence of Hepatocellular Carcinoma Less Than 3 cm in Diameter
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Yang Yin Fu Zheng Jie Du therapy|OTHER: Routine medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair
Status: COMPLETED
Conditions: Azygos Vein Preservation Versus Disconnection|Tracheo-Esophageal Fistula With Atresia of Esophagus|Leak, Anastomotic|Stricture Esophagus|Pneumonitis; Postoperative
Interventions: PROCEDURE: EA/TOF primary repair with Azygos vein preservation|PROCEDURE: EA/TOF primary repair with Azygos vein sacrifice (disconnection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Showing Photographs, Videos and Live Images of Their Babies to Mothers During Milking
Status: ENROLLING_BY_INVITATION
Conditions: Breast Milk Expression|Breast Milk Collection|Mother-Infant Interaction
Interventions: BEHAVIORAL: Photograph|BEHAVIORAL: Video|BEHAVIORAL: Live Broadcast|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Healthy Expectations - A Program for Pregnant Women Experiencing Depressive Symptoms
Status: COMPLETED
Conditions: Depressive Symptoms|Pregnancy
Interventions: BEHAVIORAL: Prenatal Walking Program|BEHAVIORAL: Postpartum Prep Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of US-guided Single-dose Thoracic Paravertebral, Erector Spinae Plane and Serratus Anterior Plane Blocks
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate the Tolerability and Effects on Epidermal Nerve Fiber Density of Multiple Low-Concentrations of NGX-1998 in Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Capsaicin Topical Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and Nivolumab
Status: WITHDRAWN
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Bempegaldesleukin (NKTR-214)|BIOLOGICAL: Nivolumab|DRUG: ⁸⁹Zr-Df-IAB22M2C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
Status: COMPLETED
Conditions: Pregnancy|Unexplained Infertility
Interventions: DRUG: Letrozole (aromatase inhibitor)|DRUG: Clomiphene Citrate|DRUG: Follicle Stimulating Hormone (gonadotropin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Status: NOT_YET_RECRUITING
Conditions: Partial Edentulism Class 3
Interventions: DEVICE: CAD/CAM metallic removable partial denture|DEVICE: Conventional metallic removable partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Diagnosis of depressive episode or post traumatic stress disorder|OTHER: No diagnosis of depressive episode or post traumatic stress disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer
Status: RECRUITING
Conditions: Cancer Metastatic
Interventions: DRUG: Paclitaxel injection|DRUG: Capecitabine tablets|DRUG: Letrozole 2.5mg|DRUG: Anastrozole 1mg|DRUG: Fulvestrant Prefilled Syringe|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Frequency and Duration of Exercise in People With Type 1 Diabetes A Randomized Crossover Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Insulin Hypoglycemia
Interventions: BEHAVIORAL: "Five sessions per period" - "Two sessions per period"|BEHAVIORAL: "Two sessions per period" - "Five sessions per period"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of LL-37 Cream on Bacteria Colonization, Inflammation Response and Healing Rate of Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: LL37|PROCEDURE: Standard Wound Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)
Status: TERMINATED
Conditions: ALS|FTD
Interventions: DRUG: WVE-004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Synovitis and Therapy Response in Inflammatory Arthritis With Contrast Enhanced Ultrasound
Status: COMPLETED
Conditions: Synovitis|Rheumatoid Arthritis
Interventions: PROCEDURE: Contrast Enhanced Ultrasound (CEUS)|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adherence Intervention for People With Low-literacy
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Stick To It|BEHAVIORAL: Standard medication adherence counseling|BEHAVIORAL: Health Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hybrid Approach to Pediatric Rehabilitation
Status: ENROLLING_BY_INVITATION
Conditions: Cerebral Palsy|Traumatic Brain Injury|Orthopedic Disorder
Interventions: OTHER: Hybrid approach (in-person and remote) to pediatric rehabilitation: A look beyond the COVID-19 crisis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Lactate Infusion in GLUT1DS Patients
Status: COMPLETED
Conditions: GLUT1 Deficiency Syndrome|GLUT1DS1|GLUT1DS2|Epilepsy|Lactic Acid Blood Increased|Ketogenic Dieting
Interventions: OTHER: sodiumlactate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain Injury
Status: UNKNOWN
Conditions: Brain Injuries|Brain Injuries, Traumatic|Brain Injury, Chronic
Interventions: DRUG: Tolcapone 200 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Anti-TNFα Naive Participants With Active Radiographic Axial Spondyloarthritis
Status: TERMINATED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Placebo|DRUG: Ustekinumab 45 mg|DRUG: Ustekinumab 90 mg|DRUG: Golimumab 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Tunnel Technique and CAF With CTG in Mandibular Gingival Recession Treatment
Status: RECRUITING
Conditions: Gingival Recession Localized Moderate
Interventions: PROCEDURE: CAF + CTG|PROCEDURE: Tunnel Technique + CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: WHO Versus IADPSG Diagnostic Criteria of Gestational Diabetes Mellitus and Their Associated Maternal and Neonatal Outcomes
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: OTHER: WHO (World Health Organisation)|OTHER: IADPSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 1 Diabetes Mellitus Patients (INSTRIDE 1)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Mylan's insulin glargine|DRUG: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 30% Nitrous oxide|DRUG: 0.4% Sevoflurane|DRUG: 0.2% sevoflurane|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation
Interventions: DRUG: Gilteritinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Evaluate the Efficacy of AR11 in Pediatric Patients With ADHD in a Laboratory Classroom Setting
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: AR11|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Intra-Operative Electron Irradiation and External Beam Irradiation After Lumpectomy in Patients With T1N0M0 and T2N0M0 Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Intra-operative radiation to tumor bed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TVEC and Preop Radiation for Sarcoma (8 ml Dose)
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Talimogene Laherparepvec|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer|Bone Metastases
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: Potassium nitrate and sodium fluoride|DRUG: Standard fluoride dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STRETCH OF RESPIRATORY MUSCLES IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Status: COMPLETED
Conditions: Dyspnea|Quality of Life|Respiratory Symptoms
Interventions: OTHER: Stretching Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexamethasone in Femural Nerve Block After Ligament Reconstruction
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexamethasone phosphate|DRUG: Paracetamol|DRUG: Morphine|DRUG: Lidocaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Fruit Juice
Status: COMPLETED
Conditions: Saliva Altered|Oral Hygiene|pH|Tooth Structure; Disorder
Interventions: OTHER: Group 1: no intervention|OTHER: Group 2: tap water gargle|DRUG: Group 3: 0.2% Chlorhexidine|OTHER: Group 4: Fluoridated tooth paste|OTHER: Group 5: Polyol containing gum|OTHER: Group 6: 1% sodium bicarbonate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: Aceclidine+tropicamide combination|DRUG: Aceclidine|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Single-arm Study: PD-1 With Recombinant Human Adenovirus Type 5 Injection for Malignant Melanomas
Status: ENROLLING_BY_INVITATION
Conditions: Malignant Melanomas
Interventions: DRUG: Recombinant Human Adenovirus Type 5 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|RADIATION: Proton radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors
Status: TERMINATED
Conditions: Anal, Colon, and Rectal Cancers|Head and Neck Cancer|Lung Cancer|Colon Cancer|Colonic Neoplasms|Colorectal Neoplasms|Colon/Rectal Cancer|Colon/Rectal Cancer Colon Cancer|Colon/Rectal Cancer Rectal Cancer|Colon/Rectal Cancer Anal Cancer|Head and Neck Cancers|Head and Neck Cancers Lip|Head and Neck Cancers Oral Cavity|Head and Neck Cancers Nasopharynx|Head and Neck Cancers Oropharynx|Head and Neck Cancers Hypopharynx|Head and Neck Cancers Larynx|Head and Neck Cancers Trachea|Lung Cancer Non-Small Cell Cancer (NSCLC)|Lung Cancer Small Cell Lung Cancer (SCLC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THAL-DEX Incorporated Into Double PBSC Autotransplantation for Untreated Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: Dexamethasone|DRUG: Zoledronic acid|DRUG: Cyclophosphamide|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strength Training for ARthritis Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: High Intensity Strength Training|BEHAVIORAL: Low Intensity Strength Training|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ciclosporin Eyedrops on Sjögren Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cyclosporin|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Assess Activity and Safety of SMT C1100 (Ezutromid) in Boys With Duchenne Muscular Dystrophy (DMD)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Ezutromid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Clinical Trial to Determine the Effect of Vagus Nerve Neurodynamics on the Neurovegetative Nerve System in People With Chronic Stress.
Status: COMPLETED
Conditions: Stress, Psychological Cumulative|Chronic Disease|Heart Rate Variability|Vagal Nerve Stimulation|Autonomic Nervous System Diseases
Interventions: OTHER: Vagus Nerve Neurodynamics|OTHER: Guided Breathing|OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-up of EUROSCUP Fixe Acetabular Cup
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Arthropathy|Hip Osteoarthritis|Hip Necrosis|Hip Fractures|Hip Dysplasia|Hip Arthritis
Interventions: DEVICE: Hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19
Status: COMPLETED
Conditions: SARS CoV 2 Infection|COVID-19
Interventions: DRUG: Bemnifosbuvir (BEM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of VR-3 Herbal Blend Intake on Acute and Chronic Stress in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: VR-3 Herbal Blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nicorandil Study to Reduce Cardiac Death After Percutaneous Coronary Intervention (PCI) in Hemodialysis Patients
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Congestive Heart Failure
Interventions: DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravitreal Conbercept Injection in Patients With Myopic Choroidal Neovascularization
Status: COMPLETED
Conditions: Myopic Choroidal Neovascularisation
Interventions: DRUG: 3+PRN|DRUG: 6+PRN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Combination of Bundles on Surgical-site Infection After Elective Colorectal Surgery
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DRUG: Bundle|PROCEDURE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment and Prevention of Acute Post-herniotomy Pain
Status: COMPLETED
Conditions: Hernia
Interventions: DRUG: Ketorolac postoperative|DRUG: postoperative Patrol|DRUG: intraoperative analgesia|DRUG: intraoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Initial Efficacy and Safety of High Intensity Focused Ultrasound 'ExAblate 4000 Type 2' for Blood Brain Barrier Disruption in Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DEVICE: transcranial magnetic resonance guided focused ultrasound BBB disruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Analgesia for Forefoot Surgery
Status: UNKNOWN
Conditions: Hallux Valgus|Conduction Block
Interventions: PROCEDURE: Ankle block|PROCEDURE: Sham ankle block|PROCEDURE: Metatarsal block|PROCEDURE: Sham metatarsal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy for the Treatment of Bipolar Disorders
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium|DRUG: Lamotrigine|DRUG: Divalproex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Two Tablet Formulations Of Doxycycline Carragenate
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: DRUG: doxycycline monohydrate tablet|DRUG: doxycycline carragenate tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trans-theoretical Model Based Home Visiting on Medication Behavior
Status: COMPLETED
Conditions: Hypertension|Medication Adherence
Interventions: BEHAVIORAL: behavior management for anti-hypertensive medication|OTHER: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Median Effective Dose of Remifentanil for the Prevention of Myoclonus Induced by Etomidate Injection
Status: NOT_YET_RECRUITING
Conditions: Etomidate|Myoclonus
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Clinical Trial of Hydronidone Capsules(F351) in Patients With Liver Fibrosis Induced by HBV Chronic Hepatitis
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Hydronidone|DRUG: Placebo|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Photodynamic Therapy ("PDT") in BCG-Unresponsive/Intolerant Non-Muscle Invasive Bladder Cancer ("NMIBC") Patients
Status: RECRUITING
Conditions: Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG
Interventions: COMBINATION_PRODUCT: Ruvidar® (TLD-1433) Bladder infusion and PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact and Cost of a Pharmacist Pneumococcal Vaccination Program With PNEUMOVAX® 23 at an Urban Senior Center
Status: COMPLETED
Conditions: Study is Open to Seniors Age 50 or Older
Interventions: BEHAVIORAL: Pharmacist Pneumococcal Vaccine Program (PPVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A New Multi-parameter Neuromonitoring System to Save Patients' Lives in Stroke and Brain Injury
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Optical Imaging
Interventions: DEVICE: NeMo Patch and NeMo Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Internet-based Multimodal Pain Program for Chronic Temporomandibular Disorder Pain
Status: COMPLETED
Conditions: Chronic Pain|Temporomandibular Disorder
Interventions: BEHAVIORAL: Internet-based multimodal pain program|DEVICE: Occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Diet Without Non-caloric Sweeteners on Gastrointestinal Symptoms in Patients With IBS and Dyspepsia
Status: UNKNOWN
Conditions: IBS - Irritable Bowel Syndrome|Functional Gastrointestinal Disorders
Interventions: OTHER: Diet without NCS|OTHER: Diet with NCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: pBFS Guided High-dose rTMS Therapy for Treatment-Resistant Obsessive-Compulsive Disorder
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder|OCD
Interventions: DEVICE: active rTMS treatment|DEVICE: sham rTMS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Nursing Intervention Program to Improve Therapeutic Adherence in Elderly People With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Medication Adherence|Myocardial Infarction
Interventions: OTHER: Nursing intervention programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of After Administrations of DWP14012 Alone and Combinations of DWP14012, Clarithromycin and Amoxicillin in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWP14012 Amg|DRUG: DWP14012 Bmg|DRUG: Clarithromycin|DRUG: Amoxicillin|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Efficacy of the Management of an Online Program of Cognitive Behavioral Therapy for Primary Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: OTHER: cognitive behavioral therapy online|OTHER: psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: PROCEDURE: Conventional Pressure Controlled SIMV|OTHER: Mid-frequency Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Abbreviated Versus Conventional Course of Dabigatran Etexilate Before Electric Cardioversion in Patients With Atrial Fibrillation (RE-SOUND Study)
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Attentional Bias Modification Training for E-cigarette Users
Status: RECRUITING
Conditions: E-cigarette Use|Tobacco Use Cessation
Interventions: BEHAVIORAL: Computerized attentional bias modification training|BEHAVIORAL: Placebo attention control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single and Multiple Doses of Different Formulations of a Prostacyclin Receptor Agonist
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Prostacyclin Receptor Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Realigning knee brace and custom orthodic|DEVICE: Non realigning knee brace and flat orthodic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Intubation Using Videolaryngoscopy Versus Conventional Direct Laryngoscopy
Status: COMPLETED
Conditions: Intubation|Laryngoscopy
Interventions: DEVICE: GlideScope videolaryngoscope (Verathon, Bothell, WA 98011)|DEVICE: Direct laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treating Patients With Traumatic Chondral Lesions With Autologous Bone Marrow Cells Derived Engineered Tissues - Engineered Osteochondral Tissue
Status: RECRUITING
Conditions: Traumatic Cartilage Injury
Interventions: COMBINATION_PRODUCT: eOCT implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Heat killed whole cell M. obuense (IMM-101) 0.1 mg|BIOLOGICAL: Heat-killed whole cell M.obuense (IMM-101) 0.5 mg|BIOLOGICAL: Heat killed whole cell M.obuense (IMM-101) 1.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Dexamethasone Implant for Retinal Detachment in Uveal Melanoma
Status: UNKNOWN
Conditions: Exudative Retinal Detachment and Uveal Melanoma
Interventions: DRUG: Dexamethasone intravitreal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Xanamem™ in Healthy Elderly Subjects
Status: COMPLETED
Conditions: Safety|Peripheral Neuropathy|Cortisol|Central Nervous System|Cognitive Function|Healthy Ageing|Small Fibre Neuropathy|Cerebrospinal Fluid|Electrocardiography
Interventions: DRUG: Xanamem|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)
Status: RECRUITING
Conditions: Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)|Descemet Membrane Endothelial Keratoplasty (DMEK)
Interventions: DRUG: Nepafenac Ophthalmic|DRUG: Dexamethasone Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Comparing Suture Anchor and Soft Tissue Pectoralis Major Tendon Techniques for Biceps Tenodesis
Status: TERMINATED
Conditions: Bicep Tendinitis|Biceps; Tenosynovitis|Biceps Tendon Disorder
Interventions: PROCEDURE: Long head of Biceps Tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Off-Label Use of Ribavirin in Management of Mucocutaneous Extrahepatic Manifestations of HCV Infection
Status: UNKNOWN
Conditions: Hepatitis C|Lichen Planus|Vasculitis|Autoimmune Diseases
Interventions: DRUG: Ribavirin|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abuse Liability and Appeal of Oral Nicotine Products
Status: RECRUITING
Conditions: Nicotine Dependence
Interventions: OTHER: Flavor|OTHER: Nicotine concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Amount of Drug That Becomes Available to the Blood Circulation When Inhaled by a Nebulizer and Dry Powder Inhaler in Healthy Subjects.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD7594
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCB vs. DES in Bifurcation Coronary Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|DCB
Interventions: DEVICE: Paclitaxel drug-coated balloons|DEVICE: Sirolimus drug-coated balloons|DEVICE: New generation drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type2 Diabetes|Diabetic Kidney Disease
Interventions: OTHER: HIPA|OTHER: Counseling PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Repeated Transcranial Magnetic Stimulation (rTMS) on the Treatment of Cocaine Addicted Patients
Status: UNKNOWN
Conditions: Cocaine Addiction|Treatment|Transcranial Magnetic Stimilation
Interventions: PROCEDURE: Transcranial Magnetic Stimulation|PROCEDURE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tadalafil to Overcome Immunosuppression During Chemoradiotherapy for IDH-wildtype Grade III-IV Astrocytoma
Status: COMPLETED
Conditions: Grade III Astrocytoma|Grade IV Astrocytoma|Astrocytoma, Grade IV|Astrocytoma, Grade III
Interventions: DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT