pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of LY3045697 After Multiple Oral Dosing in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY3045697|DRUG: Placebo|DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: BАbykids Spray In Common Cold
Status: COMPLETED
Conditions: Common Cold|Rhinitis Viral
Interventions: DEVICE: Healsea Babykids|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Subcutaneously Administered PL-3994 in Subjects With Controlled Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: PL3994|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of a Novel Dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
Status: COMPLETED
Conditions: Transplant;Failure,Kidney
Interventions: DIAGNOSTIC_TEST: Natera KidneyScan|OTHER: Clinical Performance and Value Vignettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacogenetics of Liver Toxicity in Patients With Multiple Sclerosis Treated With Fingolimod
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: GENETIC: Genetic polymorphism|DIAGNOSTIC_TEST: Measurement of fingolimod and fingolimod-phosphate concentrations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: DMARDs|DRUG: Oral Corticosteroids|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study of De-immunized DI-Leu16-IL2 Immunocytokine Administered in Participants With B-cell NHL
Status: TERMINATED
Conditions: B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: DI-Leu16-IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasoactive Drugs in Real World Practice
Status: COMPLETED
Conditions: Vasoconstrictor Choice on Acute Variceal Bleeding
Interventions: DRUG: Somatostatin|DRUG: Terlipressin|DRUG: Pantoprazole|DEVICE: Endoscopic variceal ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Arctuvan|DRUG: Fosfomycin|DRUG: Placebo to Arctuvan|DRUG: Placebo to Fosfomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality and Congenital Diaphragmatic Hernia
Status: COMPLETED
Conditions: Virtual Reality|Congenital Diaphragmatic Hernia|Children
Interventions: OTHER: Traditional physical therapy program|OTHER: Virtual reality-based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the DJO Brace With the Motion Intelligence Platform in the Postoperative Total Knee Arthroplasty Patient
Status: TERMINATED
Conditions: Total Knee Replacement
Interventions: DEVICE: DJO X4 brace with Motion Intelligence Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Function Integrity of Neck Anatomy in Thyroid Surgery
Status: RECRUITING
Conditions: Thyroid Carcinoma|Thyroid Nodule (Benign)|Ablation; Retina
Interventions: PROCEDURE: Intraoperative thermal ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|DRUG: sitagliptin|DRUG: glimepiride|DRUG: metformin|BIOLOGICAL: placebo albiglutide|DRUG: placebo sitagliptin|DRUG: placebo glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orthopedic Manual Therapy vs Foam Roller on Flexibility, Joint Range of Motion, rm and Vertical Jump
Status: COMPLETED
Conditions: Athletes
Interventions: OTHER: Finding-oriented orthopedic manual therapy treatment combined with foam roller|OTHER: Foam roller treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Licorice|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling
Status: COMPLETED
Conditions: Shoulder Pain|Chronic Pain|Musculoskeletal Injury
Interventions: DEVICE: Dry Needling|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of 23 Hour Surgery Model in a Tertiary Hospital
Status: COMPLETED
Conditions: Ambulatory Surgery|Laparoscopy|Shoulder Impingement Syndrome|Ovarian Cysts|Cholecystolithiasis|Appendicitis|Gynecologic Surgical Procedures|Ambulatory Surgical Procedures|Neurosurgery
Interventions: OTHER: 23 h surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Milnacipran Prevent Depressive Symptoms in Patients With Acute Stroke?
Status: UNKNOWN
Conditions: Ischemic Stroke|Depression
Interventions: DRUG: milnacipran|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determine Effect of Enzalutamide (MDV3100) on the Androgen Signaling Pathway in Correlation With the Anti-tumor Effects of Enzalutamide
Status: COMPLETED
Conditions: Metastatic Progressive Castration-resistant Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Cancer
Interventions: RADIATION: Radiation|PROCEDURE: Transoral Surgery (TOS) + Neck Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Insomnia
Interventions: BEHAVIORAL: CBT-I|PROCEDURE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SRT501 in Subjects With Colorectal Cancer and Hepatic Metastases
Status: COMPLETED
Conditions: Neoplasms, Colorectal
Interventions: DRUG: Placebo|DRUG: SRT501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cesarean Section Defect Mechanism and Transvaginal Repair
Status: NOT_YET_RECRUITING
Conditions: Cesarean Scar Defect; Transvaginal Diverticulum Resection
Interventions: PROCEDURE: Suture method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Predictors of Response to a Peer-Mediated Intervention for Preschoolers With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Nonverbal Communication
Interventions: BEHAVIORAL: Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Rituximab as Treatment of Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Adductor Canal Block With a New Catheter - Primary Placement and Secondary Repositioning
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Lidocaine|PROCEDURE: LAX insertion of catheter|PROCEDURE: SAX insertion of catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Controlled Trial to Demonstrate a Reduction in the Number of Oliguria Events in Patients Being Managed in a Critical Care Unit, Following Cardiac Surgery, When a Novel Oliguria Prediction Tool (STABILITY UO) is Used to Identify Patients at Risk, Compared to Standard of Care.
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DEVICE: Stability UO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peri-neural Dexmedetomidine as an Adjuvant to Bupivacaine Induced Paravertebral Block in Patients Undergonig Thoracotomy
Status: COMPLETED
Conditions: Acute Post-thoracotomy Pain
Interventions: DRUG: dexmedetomidine bupivacaine|DRUG: Bupivacaine saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JINZHEN for Treatment of Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: JINZHEN Granules for Oral Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RATME vs LATME in Middle and Low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Total Mesorectal Excision|Rectal Neoplasms|Robotic Surgical Procedures|Laparoscopy
Interventions: PROCEDURE: Robotic-assisted total mesorectal excision|PROCEDURE: laparoscopic-assisted total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effectiveness of Low Level Laser Therapy (LLT) Combined With Acupuncture
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: DEVICE: B-Cure Laser Pro and needles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomised Open-label Multicenter Study Evaluating Ciprofloxacin in Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis|Alcoholic Cirrhosis
Interventions: DRUG: Ciprofloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pilates Exercises on Stress Urinary Incontinence in Posmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Urinary Stress Incontinence
Interventions: OTHER: Pilates exercise - pelvic floor exercise - home advices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Effectiveness Study in Heart Transplant Patients of Rejection Surveillance With Cell-free DNA Versus Endomyocardial Biopsy
Status: RECRUITING
Conditions: Heart Transplant Failure and Rejection
Interventions: DIAGNOSTIC_TEST: The Prospera™ Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Dose Pharmacokinetic (PK) Study Of Paroxetine CR(12.5-37.5mg) In Healthy Chinese Subjects
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Paroxetine controlled release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
Status: UNKNOWN
Conditions: Melasma
Interventions: DEVICE: 755-nm picosecond alexandrite laser with topical 2% hydroquinone|DRUG: topical 2% hydroquinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Home Rehabilitation on State of Patients With PAH, HFREF and IHD
Status: COMPLETED
Conditions: Pulmonary Hypertension|Heart Failure With Reduced Ejection Fraction|Ischemic Heart Disease
Interventions: OTHER: home cardiac rehabilitation and respiratory rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Internal Jugular Vein Ultrasound and Electrical Cardiometry
Status: COMPLETED
Conditions: Coronary Bypass Stenosis|Coronary Artery Bypass Grafting Surgery
Interventions: PROCEDURE: Coronary Artery Bypass Grafting surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACS
Status: UNKNOWN
Conditions: Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: low-dose ticagrelor|DRUG: conventional-dose ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Training and Cancer-a Multicenter Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer
Interventions: BEHAVIORAL: high intensity exercise|BEHAVIORAL: low/medium intensity exercise|BEHAVIORAL: Behavioral medicine strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Leflunomide Tablets Under Fed Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Leflunomide|DRUG: ARAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improvement In Scratch Behavior And Sleep In Patients With Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole 2%|DRUG: Vehicle treatment|DEVICE: Accelerometry device for children|DEVICE: Accelerometry device for adult caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis
Status: UNKNOWN
Conditions: Pain, Procedural
Interventions: PROCEDURE: Cryotherapy|PROCEDURE: Buccal local anesthetic infiltration using articaine 4% 1:100000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rectal Safety and Acceptability Study of Tenofovir 1% Gel
Status: COMPLETED
Conditions: Rectal Microbicides
Interventions: DRUG: Tenofovir 1% gel|DRUG: 2% N-9 gel|DRUG: HEC Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: 5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|MDS/MPN Crossover Syndromes
Interventions: DRUG: 5-azacytidine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study is to Assess Efficacy and Safety of Tacrolimus in Active Rheumatoid Arthritis Patients Who Showed Unsuccessful Response to Existing Disease Modifying Antirheumatic Drugs (DMARDs)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: 6-mercaptopurine, Methotrexate|DRUG: 6-mercaptopurine, Methotrexate, Vincristine, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Valproic Acid and Epirubicin in Solid Tumor Malignancies
Status: COMPLETED
Conditions: Neoplasms, Advanced
Interventions: DRUG: Valproic acid|DRUG: Epirubicin|DRUG: 5-fluorouracil|DRUG: Cyclophosphamide.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile-based Online Social Network Intervention to Increase Physical Activity
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: PennFit mobile individual intervention|BEHAVIORAL: PennFit mobile online network intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison Between Dexmedetomidine and Propofol-fentanyl Infusions for Sedation for Colonoscopy Procedures
Status: COMPLETED
Conditions: Anxiety and Fear
Interventions: DRUG: Patients who received Dexmedetomodine|DRUG: patients who received propofol-fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effectiveness Study of the BOA(R)-Constricting IV Band
Status: TERMINATED
Conditions: Catheterization, Peripheral
Interventions: DEVICE: BOA(R)-Constricting IV Band|DEVICE: Standard elastic constricting band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Technology-Enhanced Acceleration of Germline Evaluation for Therapy, TARGET Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: OTHER: Interview|OTHER: Internet Based Intervention|OTHER: Survey Administration|OTHER: Genetic Counseling|GENETIC: Genetic Testing|OTHER: Survey Administration|OTHER: Genetic Counseling|OTHER: Internet-Based Intervention|GENETIC: Genetic Testing|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Mobile Health Education on Adaptation to Stoma, Self-efficacy, and Peristomal Lesions
Status: COMPLETED
Conditions: Nurse's Role|Patient Compliance|Peristomal Skin Complication|Self Efficacy
Interventions: OTHER: Assigned Interventions STOMA-M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease
Status: TERMINATED
Conditions: Cushings Disease
Interventions: DRUG: Pasireotide with or without cabergoline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Euthyroid Hypothyroxinemia in Metastatic Breast Carcinoma
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Thyroid Dysfunction
Interventions: DRUG: Triiodothyronine (T3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Versus Sb-taxanes As First-Line Treatment in Advanced Ovarian Cancer
Status: RECRUITING
Conditions: Epithelial Ovarian Carcinoma Stage III|Epithelial Ovarian Carcinoma Stage IV|Fallopian Tube Carcinoma Stage III|Fallopian Tube Carcinoma Stage IV|Primary Peritoneal Carcinoma Stage III|Primary Peritoneal Carcinoma Stage IV
Interventions: DRUG: nab-paclitaxel combined with carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Impact of Suction- Assisted Laryngoscopy and Airway Decontamination on Intubation Times
Status: UNKNOWN
Conditions: Contaminated Airway
Interventions: PROCEDURE: Training on Suction Assisted Laryngoscopy and Airway Decontamination|PROCEDURE: No Training on Suction Assisted Laryngoscopy and Airway Decontamination Provided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation
Status: COMPLETED
Conditions: Intubation Complication
Interventions: DRUG: Etomidate|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic on the Innate and Adaptive Host Response to Rhinovirus (EPIARR)
Status: COMPLETED
Conditions: Common Cold
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium lactis Bl-04|DIETARY_SUPPLEMENT: Placebo|BIOLOGICAL: Rhinovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transitioning Youth Out of Homelessness 2.0 (TYOH 2.0)
Status: COMPLETED
Conditions: Homelessness|Youth
Interventions: BEHAVIORAL: Identity Capital Intervention (Coach + Co-designed Leadership Guide)|OTHER: Monthly Rent Subsidies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery
Status: UNKNOWN
Conditions: Postoperative Wound Haemorrhage
Interventions: DRUG: Tranexamic acid|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Modulation of Cognitive Flexibility by Tyrosine Depletion and Transcranial Direct Current Stimulation
Status: COMPLETED
Conditions: Cognitive Flexibility
Interventions: COMBINATION_PRODUCT: Sham tDCS and tyrosine depleted drink|COMBINATION_PRODUCT: Anodal tDCS and tyrosine depleted drink|COMBINATION_PRODUCT: Sham tDCS and balanced drink|COMBINATION_PRODUCT: Anodal tDCS and balanced drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthesia for Obese Patients: Desflurane Versus Xenon
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Desflurane|DRUG: Xenon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Relationship and Coparenting Education Curricula for Adolescent Parents
Status: UNKNOWN
Conditions: Romantic Relationship Skills|Coparenting Skills
Interventions: BEHAVIORAL: Full Intervention #1|BEHAVIORAL: Full Intervention #2|BEHAVIORAL: Partial Intervention #1|BEHAVIORAL: Partial Intervention #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Status: RECRUITING
Conditions: Anaplastic Astrocytoma|Anaplastic Astrocytoma, Not Otherwise Specified|Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant|Glioblastoma|Glioblastoma, Not Otherwise Specified|Malignant Glioma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Local Register Study For Major Depression Of Paroxetine Controlled Release
Status: COMPLETED
Conditions: Depressive Disorder, Major|Major Depressive Disorder (MDD)
Interventions: DRUG: Paroxetine CR|DRUG: Paroxetine IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Advanced Cancer
Interventions: PROCEDURE: Complete Preservation of Denonvilliers' Fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients
Status: UNKNOWN
Conditions: Schizophrenia|Micrognathia
Interventions: DRUG: Atypical Antipsychotic|OTHER: atypical antipsychotic combined with MECT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Probiotics on the Intestinal Microbiota of Pediatric Patients
Status: NOT_YET_RECRUITING
Conditions: Neurodevelopmental Disorders
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spaso Versus Self-assisted Maneuver for Anterior Shoulder Dislocation
Status: COMPLETED
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: Boss-Holzach-Matter method|PROCEDURE: Spaso method|DRUG: Anti-Inflammatory Agents, Non-Steroidal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: DRUG: Acarbose|DRUG: Placebo Oral Tablet|DRUG: Exendin (9-39)|DRUG: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)
Status: COMPLETED
Conditions: Graft Vs Host Disease
Interventions: DRUG: Prochymal® - 2 Million cells/kg|DRUG: Prochymal®- 8 Million cells/kg|DRUG: Methylprednisolone|DRUG: Prednisone|DRUG: Cyclosporine|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Renal Impairment on the Pharmacokinetics, and Safety of Megestrol Acetate Concentrated Suspension
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Megestrol acetate concentrated suspension 125 mg/mL|DRUG: Megestrol acetate concentrated suspension 125 mg/mL|DRUG: Megestrol acetate concentrated suspension 125 mg/mL|DRUG: Megestrol acetate concentrated suspension 125 mg/mL|DRUG: Megestrol acetate concentrated suspension 125 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Phase 2 Study of Neoadjuvant Docetaxel, Oxaliplatin, S-1 in Patients With Unresectable Locally Advanced or Distant Metastasis Limited to Lymph Node Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasm
Interventions: DRUG: Docetaxel injection, oxaliplatin, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Farsi Diabetes Self-management Education (FDSME) Program for People With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: FDSME group|BEHAVIORAL: FDSME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: aerosolized aztreonam|DRUG: aerosolized vancomycin|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Manual Therapy Plus Cervical Stabilization Exercise in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Manual Therapy|OTHER: Cervical Stabilazation Exercise (CSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intensive Multifactorial Therapy on Endothelial Function in Newly Diagnosed Type 2 Diabetes
Status: UNKNOWN
Conditions: Endothelial Dysfunction
Interventions: DRUG: Intensive multifactorial group|DRUG: conventional multifactorial therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Botulinum Toxin A on Detrusor Overactivity and Renal Function in Chronic Spinal Cord Injured Patients
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Environmental Factors and Embryonic Development Project
Status: UNKNOWN
Conditions: Spontaneous Abortion|Fetal Death|Stillbirth|Birth Defects|Preterm Birth|Low Birth Weight|Pregnancy With Medical Condition (Non-Specific)|Gestational Diabetes|Gestational Hypertension
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Cilostazol and Aspirin on Cerebral Small Vessel Disease
Status: UNKNOWN
Conditions: Cerebral Small Vessel Disease
Interventions: DRUG: aspirin|DRUG: cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Crisis|Veno-occlusive Disease
Interventions: DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and Adolescents
Status: COMPLETED
Conditions: Refractory Tumors|Malignant Tumors
Interventions: DRUG: Topotecan, Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Tendinopathy Exercise Trial
Status: COMPLETED
Conditions: Rotator Cuff Tendinitis
Interventions: OTHER: Low Load Exercises|OTHER: Progressive Heavy Strength Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platelet-rich Plasma Injection Compare With Corticosteroid in Pes Anserinus Pain Syndrome
Status: NOT_YET_RECRUITING
Conditions: Pes Anserine Bursitis|Steroid Injection|PRP Injection
Interventions: DRUG: PRP injection|DRUG: corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: dutasteride 0.5mg once daily for 4 years|DRUG: tamsulosin 0.4mg once daily for 4 years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Quality of Life of Poly-amide Complete Dentures
Status: UNKNOWN
Conditions: Denture, Complete
Interventions: OTHER: poly-amide|OTHER: poly-methyl methacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumor|Medulloblastoma
Interventions: DRUG: [18F]DPA714
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Healthy Volunteer Study to Evaluate for a Single Dose of 4 Different Tablets of DPOC-4088 the Absorption and Elimination From the Body and the Potential Effect on Blood Clotting
Status: COMPLETED
Conditions: Deep Vein Thrombosis Leg
Interventions: DRUG: DPOC-4088|DRUG: DPOC-4088|DRUG: DPOC-4088|DRUG: DPOC-4088
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|OTHER: Clinical Observation|PROCEDURE: Computed Tomography|OTHER: Gallium Ga 68 Gozetotide|DRUG: Lutetium Lu 177 Vipivotide Tetraxetan|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Combined With Cisplatin as First Line in Patients With Metastatic Non-small Cell Lung Cancer
Status: SUSPENDED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: cisplatin, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetic Study in Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Berberine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Plus Diclofenac Versus Bupivacaine Alone for Postoperative Pain Relief in Gynecologic Cancer Patients
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: OTHER: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Levonorgestrel-releasing Intrauterine Device and Dydrogestreone on Quality of Life and Sexual Life in Patients With Abnormal Uterine Bleeding.
Status: UNKNOWN
Conditions: Abnormal Uterine Bleeding
Interventions: OTHER: SF-36 Scores
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Healthy Microbiome, Healthy Mind
Status: RECRUITING
Conditions: Critical Illness|COVID-19|PICS|Cognitive Impairment|Mental Health Impairment|Weakness, Muscle|Dysbiosis
Interventions: BEHAVIORAL: Fermented Food Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: a Single HYAJOINT Plus Combined With a Single PPR Versus a Single PRP for Knee OA
Status: COMPLETED
Conditions: Knee OA
Interventions: COMBINATION_PRODUCT: a single intraarticular injection of HYAJOINT Plus (3 ml) followed by 3 ml PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegaptanib Therapy in Non-Infectious Uveitic Cystoid Macular Edema
Status: COMPLETED
Conditions: Uveitis|Cystoid Macular Edema
Interventions: DRUG: Pegaptanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With HBV-ACLF and Sepsis
Status: NOT_YET_RECRUITING
Conditions: Acute-On-Chronic Liver Failure|Sepsis
Interventions: DEVICE: double plasma cytokine adsorption system with sequential low-dose plasma exchange|OTHER: plasma exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Severity of Liver Disease by a 13C Octanoate Breath Test (OBT)
Status: TERMINATED
Conditions: Metabolic Syndrome|Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Sodium Octanoate Breath Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An International Prospective, Observational, Multi-centre Study on the Duration of Pre-operative Liquid Fasting
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Hypertension|Ischaemic Heart Disease|Comorbidities and Coexisting Conditions|Fasting|Fasting, Time Restricted
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability Of Two Formulations Of Moroctocog Alfa (AF-CC)
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: moroctocog alfa (AF-CC)|DRUG: moroctocog alfa (AF-CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Effectiveness of the Induced Reflex Cough Test Plus Urodynamics to Identify Stress Urinary Incontinence in Female Subjects With a History of Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: IRCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Computed Tomography for Early Detection of Cancer in Women Who Are at Risk for Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: bronchoalveolar lavage|OTHER: screening questionnaire administration|OTHER: sputum cytology|PROCEDURE: bronchoscopic and lung imaging studies|PROCEDURE: bronchoscopy|PROCEDURE: computed tomography|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children
Status: COMPLETED
Conditions: Gastrointestinal|Tolerance
Interventions: OTHER: Erythritol drink|OTHER: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Status: RECRUITING
Conditions: Gender Dysphoria, Adolescent
Interventions: DRUG: Depo-subQ Provera Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Fructose and Exercise on Hepatic Lipid Metabolism
Status: COMPLETED
Conditions: Metabolism
Interventions: BEHAVIORAL: weight maintenance, low sugar diet|BEHAVIORAL: weight maintenance, high fructose diet|BEHAVIORAL: weight maintenance, high fructose diet+ exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion
Status: NOT_YET_RECRUITING
Conditions: Bronchopulmonary Dysplasia|Necrotizing Enterocolitis|Intracranial Hemorrhages
Interventions: COMBINATION_PRODUCT: Continuous amnioinfusion with Amnion Flush Solution through the intraamniotic catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Lenalidomide, Bendamustine and Prednisone (RBP) in Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide, Bendamustine, Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mericitabine in Combination With Boceprevir and Pegasys/Copegus in Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Copegus|DRUG: Copegus|DRUG: Pegasys|DRUG: Pegasys|DRUG: boceprevir|DRUG: boceprevir|DRUG: mericitabine|DRUG: mericitabine placebo|DRUG: boceprevir placebo|DRUG: boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Rifampicin (CYP Inducer) on Blood Levels and Safety of Olaparib in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Solid Tumours
Interventions: PROCEDURE: Pharmacokinetic sampling|DRUG: Rifampicin|DRUG: Olaparib tablet dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Suberoylanilide Hydroxamic Acid in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Component Research on VATS and NIVATS
Status: COMPLETED
Conditions: Thoracoscopy|Anesthesia; Functional|Tracheal Intubation
Interventions: PROCEDURE: DSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Safety, and Quality of Life and Sexuality Impact
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: Leonardo® Diode laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Micronutrient Supplementation in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Placebo|DRUG: Forceval plus 50 micrograms Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT