pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chiglitazar Added to Metformin for Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Chiglitazar 32mg|DRUG: Chiglitazar 48mg|DRUG: Placebo|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Bilateral Salpingectomy and Laparoscopic Myomectomy
Status: UNKNOWN
Conditions: Abnormal Uterine Bleeding, Unspecified
Interventions: PROCEDURE: Prophylactic bilateral salpingectomy|PROCEDURE: Laparoscopic myomectomy without PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability and Explorative Efficacy of DM-101PX in Birch Pollen Allergic Participants
Status: COMPLETED
Conditions: Birch Pollen Allergy
Interventions: BIOLOGICAL: DM-101PX|BIOLOGICAL: Placebo to Match DM-101PX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pacemaker Upgrade to Cardiac Resynchronisation Therapy in Patients With Left Ventricular Dysfunction Dependant Upon Right Ventricular Pacing
Status: COMPLETED
Conditions: Left Ventricular Function Systolic Dysfunction
Interventions: PROCEDURE: Cardiac resynchronisation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase I
Status: COMPLETED
Conditions: Opioid Use|Chronic Pain
Interventions: BEHAVIORAL: Yoga classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: AgingPLUS: Promoting Physical Activity in Adults
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: AgingPLUS|BEHAVIORAL: Active Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of BST-236 in Newly Diagnosed Acute Myeloid Leukemia Patients, Unfit for Standard Induction Therapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: BST-236
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress, Carbohydrate Metabolism Disorders and G6PD Deficiency
Status: NOT_YET_RECRUITING
Conditions: G6PD Deficiency|Carbohydrate Metabolism Disorder|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Alpha-lipoic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Ramipril 10 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ramipril10 mg Capsules, single dose|DRUG: Atlace® 10 mg capsules, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Autologous Bronchial Basal Cells Transplantation for Treatment of Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: Bronchial basal cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mindfulness Intervention as Myocardial Infarction Rehabilitation Additive (MIMIRA) Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Depressive Symptoms
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy
Status: COMPLETED
Conditions: Pediatric Oncology
Interventions: DRUG: Regorafenib (BAY73-4506)|DRUG: Vincristine (Cellcristin®)|DRUG: Irinotecan (Irinotecan Cell pharm®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nutritional Management of Post COVID-19 Cognitive Symptoms
Status: RECRUITING
Conditions: Long COVID
Interventions: DIETARY_SUPPLEMENT: medium chain triglyceride oil|DIETARY_SUPPLEMENT: Safflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Feeding Different Levels of Docosahexaenoic Acid to Pre-School Children
Status: TERMINATED
Conditions: Measurement of Docosahexaenoic Acid Levels in Pre-school Children
Interventions: OTHER: Milk-based beverage without DHA|OTHER: Milk-based beverage with DHA at mid level|OTHER: Milk-based beverage with DHA at high level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Association Between Preoperative HALP and Immediate Postoperative Outcomes
Status: COMPLETED
Conditions: Hemoglobins|Albumins|Platelets|Lymphocytes|Morbidity|Mortality|Whipples Procedure
Interventions: OTHER: pantients undergoing pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-PSMA-11 Efficacy in Detecting BCR Prostate Cancer in Chinese Patients
Status: RECRUITING
Conditions: Biochemical Recurrence of Malignant Neoplasm of Prostate|Prostate Cancer|BCR Prostate Carcinoma
Interventions: DRUG: 68Ga-PSMA-11|OTHER: PET/CT or PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Clinical Study of LTC004 in Patients With Advanced Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Unresectable or Metastatic Sarcoma
Interventions: DRUG: LTC004
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase2, Single Group, Open Clinical Trial to Evaluate the Efficacy and Safety of Roflumilast in Symptomatic Bronchiectasis Patients
Status: UNKNOWN
Conditions: Symptomatic Bronchiectasis
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma|Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Double-Expressor Lymphoma|EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|High Grade B-Cell Lymphoma, Not Otherwise Specified|Neoplastic Cells With Double Expression of MYC and BCL2 Proteins Present|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|PROCEDURE: Lumbar Puncture|PROCEDURE: Positron Emission Tomography|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Venetoclax|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial, Ovarian or Cervical Cancer (AL3818-US-001)
Status: TERMINATED
Conditions: Endometrial Cancer|Ovarian Cancer|Cervical Cancer
Interventions: DRUG: AL3818
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Clinical Test of the Ultracore Repose® Mattress to Prevent Pressure Ulcers Cat. II-IV in Nursing Homes
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Ultracore Repose® mattress|OTHER: experiences and perceptions of healthcare workers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IBI188 Combination Therapy in Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|Lung Adenocarcinoma|Osteosarcoma
Interventions: DRUG: IBI188|DRUG: GM-CSF|DRUG: Cisplatin/Carboplatin|DRUG: Bevacizumab|DRUG: Sintilimab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.
Status: COMPLETED
Conditions: Oropharyngeal Cancer|Squamous Cell Carcinoma to the Head and Neck
Interventions: DRUG: Lyrica 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health
Status: COMPLETED
Conditions: Body Composition, Beneficial|Paresis|Impaired Glucose Tolerance
Interventions: OTHER: wt loss|OTHER: Meal Pattern|OTHER: meal pattern|DIETARY_SUPPLEMENT: even|DIETARY_SUPPLEMENT: skew
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Concomitant Hip Arthroscopy During PAO
Status: RECRUITING
Conditions: Hip Dysplasia
Interventions: PROCEDURE: Periacetabular osteotomy|PROCEDURE: Periacetabular osteotomy with hip arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of a Treatment Consisting of Peg Interferon Alfa + Ribavirin + Daclatasvir in HCV Genotype 1 and 4 Treatment naïve Patients
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon alfa 2a|DRUG: Ribavirin|DRUG: Placebo matching Daclatasvir|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating APG777 in Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: APG777|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation|Renal Transplantation
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Cyclosporin A|DRUG: Enteric Coated Mycophenolate Sodium (EC-MPS)|DRUG: Mycophenolate mofetil (MMF)|DRUG: Corticosteroids|DRUG: Simulect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium in Acute Kidney Injury
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Placebo oral capsule|DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PROton Versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy
Status: RECRUITING
Conditions: Esophageal Cancer|Radiotherapy|Side Effect|Proton Therapy
Interventions: RADIATION: Photon Radiotherapy|RADIATION: Proton Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duodenoscope Disinfect Study
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatogram (ERCP)
Interventions: OTHER: Double HLD|OTHER: HLD/ETO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Examining tDCS Effect on Cannabis Use Disorder in Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Cannabis-Induced Disorder
Interventions: DEVICE: Transcranial direct current stimulation (tDCS) active|DEVICE: Transcranial direct current stimulation (tDCS) non active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning
Status: COMPLETED
Conditions: Organophosphate Poisoning
Interventions: DRUG: Standard care|DRUG: Standard care+ 2.5 mg Salbutamol|DRUG: Standard care+ 5 mg Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBA, Safety and Tolerability of Sanfetrinem Cilexetil
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Sanfetrinem Cilexetil|DRUG: Amoxicillin/clavulanic acid|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver Failure
Status: RECRUITING
Conditions: Hepatic Encephalopathy|Acute-On-Chronic Liver Failure
Interventions: DIAGNOSTIC_TEST: Liquid Chromatography-Mass Spectrometry Method to identify bilirubin molecular species
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability and Pharmacokinetic Measures of H. Procumbens Extract
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Enteric coated Devil's Claw|DRUG: Non-enteric coated Devil's Claw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions
Status: COMPLETED
Conditions: HIV Infections|Hepatic Insufficiency
Interventions: DRUG: nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Cysteamine|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive REmediation After Trauma Exposure Trial = CREATE Trial
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder|Traumatic Brain Injury
Interventions: DRUG: Methylphenidate Hydrochloride 20 mg|DRUG: Placebo Capsule|DRUG: Galantamine 12 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Dental Implant & ADM|PROCEDURE: Dental Implant & ADM & bone xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 PUFA on Lipids, Inflammatory Factors and Body Composition in Patients With Hyperlipidemia
Status: UNKNOWN
Conditions: Hyperlipidemias
Interventions: OTHER: fish oil with omega-3 PUFA|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With EGFR-Positive Advanced Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: MRG003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary Events
Status: COMPLETED
Conditions: Parkinson's Disease|Hyperprolactinemia
Interventions: OTHER: Retrospective study-|OTHER: Retrospective study-|OTHER: Retrospective study-|OTHER: Retrospective study-
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies
Status: COMPLETED
Conditions: Myeloid Malignancies
Interventions: DRUG: GvHD prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Myofascial Trigger Point Pressure Release on Tinnitus Patients
Status: COMPLETED
Conditions: Tinnitus|Myofascial Trigger Points
Interventions: OTHER: Myofascial trigger point pressure release (deactivation)|OTHER: Placebo myofascial trigger point pressure release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coagulation Parameters With Albumin in Decompensated Cirrhosis (CoPA-D).
Status: NOT_YET_RECRUITING
Conditions: Decompensated Cirrhosis
Interventions: BIOLOGICAL: Albumin|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of 1064-nm Picosecond Laser With Microlens Array for Pore Tightening; a Pilot Study
Status: UNKNOWN
Conditions: Enlarged Pores
Interventions: DEVICE: Fractional picosecond 1064 nm laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Integrative Medication Self-Management Intervention to Promote Medication Adherence
Status: COMPLETED
Conditions: Medication Adherence|Chronic Disease
Interventions: BEHAVIORAL: Integrative Medication Self Management (IMedS) Intervention|BEHAVIORAL: Standard Care Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating Penicillin G and Ceftriaxone as Therapies for Presumed Neurosyphilis in HIV Seropositive Individuals
Status: COMPLETED
Conditions: HIV Infections|Neurosyphilis
Interventions: DRUG: Penicillin G potassium|DRUG: Ceftriaxone sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Electrostimulation of Shoulder Girdle and Quadriceps Muscles in Facioscapulohumeral Muscular Dystrophy Patients
Status: COMPLETED
Conditions: Facioscapulohumeral Muscular Dystrophy
Interventions: PROCEDURE: electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in EDs in Pakistan
Status: COMPLETED
Conditions: Dehydration|Gastroenteritis|Vomiting|Diarrhea
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: IMP4297(20mg)|DRUG: IMP4297(10mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: MK-2206|DRUG: AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinitis Due to Grass Pollen|Healthy Volunteers
Interventions: BIOLOGICAL: B244 suspension|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide-Ondansetron vs. Metoclopramide Therapy for Treatment of Nausea and Vomiting Post Laparoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: Dual therapy|OTHER: Monotherapy|OTHER: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Adjuvant Cisplatin With Either Genomic-Guided Vinorelbine or Pemetrexed for Early Stage Non-Small-Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Vinorelbine followed by Cisplatin|DRUG: Pemetrexed followed by Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lofexidine for Inpatient Opiate Detox in Singapore
Status: COMPLETED
Conditions: Opiate Dependent Patients Who Are Undergoing Inpatient Detoxification in Singapore
Interventions: DRUG: Lofexidine|DRUG: Diazepam|DRUG: Placebo for Lofexidine|DRUG: Placebo for Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-derived-organoid (PDO) Guided Versus Conventional Therapy for Advanced Inoperable Abdominal Tumors
Status: WITHDRAWN
Conditions: Organoids
Interventions: DRUG: PDO-guided treatment|DRUG: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of Two Variants of Prolonged - Released Tacrolimus (Advagraf vs. Envarsus ) in Patients After Liver Transplantation : Single Center Randomised Control Trial
Status: UNKNOWN
Conditions: Liver Transplant Rejection|Immunosuppression
Interventions: DRUG: Envarsus|DRUG: Advagraf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Fatty Liver on Hepatitis B Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Fatty Liver Disease|Chronic Hepatitis B|Antiviral Treatment
Interventions: DRUG: Entecavir；Tenofovir Disoproxil Fumarate (TDF)； Tenofovir alafenamide fumarate (TAF)；Interferons
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Effexor XR in Chinese Subjects With Major Depressive Disorder
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Effexor XR|OTHER: Effexor XR discontinue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of 10XB-101 in Adults With Bilateral Flank Adiposity
Status: ACTIVE_NOT_RECRUITING
Conditions: Subcutaneous Fat Disorder
Interventions: DRUG: 10XB-101 Solution for Injection, 6.0%|DRUG: Placebo Solution for Injection (no active ingredient)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Everolimus in Metastatic Renal Cell Carcinoma After Failure of First Line Therapy With Sunitinib or Pazopanib
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma (mRCC)
Interventions: DRUG: Everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALXN1830 in Patients With Warm Autoimmune Hemolytic Anemia
Status: WITHDRAWN
Conditions: Warm Autoimmune Hemolytic Anemia
Interventions: BIOLOGICAL: ALXN1830|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg for Acute Pain
Status: COMPLETED
Conditions: Moderate-to-severe Acute Pain
Interventions: DRUG: sufentanil sublingual 30 mcg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Occult Malignancy in Patients With Idiopathic Venous Thromboembolism
Status: COMPLETED
Conditions: Venous Thromboembolism|Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DEVICE: Comprehensive computed tomography of the abdomen/pelvis|OTHER: Limited Malignancy Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Mexartan Potassium Tablets (AZL-M) and Calcium Channel Blockers (CCB) in the Treatment of Adults With Essential Hypertension in Chinese Population: a National Multicenter, Prospective, Observational Study
Status: RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: Azilsartan Medoxomil Potassium Tablet|DRUG: Nifedipine Sustained -release Tablets|DRUG: Levoamlodipine Maleate Table
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of TissueGene-C in Degenerative Joint Disease of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: TissueGene-C|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis
Interventions: OTHER: Hemodialysis|DRUG: Patiromer Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Giomer Composite Versus Resin-Modified Glass Ionomer in Cervical Caries Lesions: A Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Caries, Cervical
Interventions: OTHER: Low Shrinkage Giomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Membranous Nephropathy
Interventions: DRUG: Obinutuzumab|DRUG: Tacrolimus|DRUG: Methylprednisolone|DRUG: Acetaminophen|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Zoladex Given Every 12 Weeks Versus Given Every Month in Advanced Breast Cancer (ABC) Pre-menopausal Women
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Goserelin acetate|DRUG: Goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sizing of the PERCEVAL® Sutureless Aortic Valve Prosthesis Using the CT: a Feasibility Study
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Sorin Perceval ® Sutureless Valve (Sorin Group Italia Srl, 13040 Saluggia, Italy), available in different sizes (S 19-21mm, M 21-23mm, L 23-25mm, XL 25-27mm)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Status: UNKNOWN
Conditions: Decay, Dental
Interventions: OTHER: chlorhexidine|OTHER: saline|OTHER: Propolis extract|OTHER: pomegranate extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH
Status: RECRUITING
Conditions: PNH|Hemolysis
Interventions: DRUG: CAN106 20 mg/kg|DRUG: CAN106 40 mg/kg|DRUG: CAN106 80 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block for Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy|Laparoscopic Surgery
Interventions: OTHER: USguided bilateral TAP block|DRUG: Morphine Patient Controlled Analgesia|DRUG: Morphine Patient Controlled Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy
Status: RECRUITING
Conditions: Medical Oncology|Integrative Oncology|Medical Nutrition Therapy
Interventions: OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protection of Cardiovascular Function With Crocin in BrEast Cancer Patients Undergoing Radiotherapy and Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: crocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP
Status: ENROLLING_BY_INVITATION
Conditions: Erythropoietic Protoporphyria
Interventions: DRUG: DISC-1459|DRUG: DISC-1459
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study Comparing EG1206A and Perjeta (Pertzumab) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 420 mg EG1206A EirGenix Pertuzumab in 14 mL Injection|DRUG: Perjeta (EU origin) 420 mg in 14 mL Injection|DRUG: Perjeta (US origin) 420 mg in 14 mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GZL Sequential CD19/CD22 CAR-T in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Zanubrutinib|DRUG: Lenalidomide|DRUG: CD19/CD22 CAR-T|DRUG: Azacitidine For Injection|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Cytomegalovirus (CMV) Vaccine mRNA-1647
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Trial of ExACT (Exercise as Airway Clearance Therapy) for People With Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: Exercise as Airway Clearance Therapy (ExACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Antioxidants (Vitamin C and E) in the Management of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Antioxidants (Vitamin C, E )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kangaroo Care on Heart Rate Variability in Late-onset Neonatal Sepsis
Status: RECRUITING
Conditions: Late-Onset Neonatal Sepsis
Interventions: PROCEDURE: Kangaroo Care (skin-to-skin contact)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
Status: COMPLETED
Conditions: ADHD|Autism|Bipolar I Disorder|Conduct Disorder|Oppositional Defiant Disorder
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance Training With tDCS for CAI
Status: COMPLETED
Conditions: Ankle Injuries and Disorders
Interventions: DEVICE: Anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SOX Combined With Sintilimab and Trastuzumab Versus SOX Regimen in the Perioperative Treatment of HER2-positive Locally Advanced Gastric Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: HER2-positive|Locally Advanced Solid Tumor|Immunotherapy|Sintilimab|S-1|Oxaliplatin|Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: sintilimab|DRUG: Trastuzumab|DRUG: S-1 plus oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension|Essential Hypertension
Interventions: DRUG: SPC1001 High|DRUG: SPC1001 Mid1|DRUG: SPC1001 Mid2|DRUG: SPC1001 Low|DRUG: SPC3001|DRUG: SPC4001|DRUG: SPC4002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hyperbaric Oxygen Therapy for Long COVID Syndrome
Status: COMPLETED
Conditions: COVID-19|Post COVID-19 Condition|Post COVID-19 Condition, Unspecified|Post COVID Condition|Post-COVID Syndrome|Post-Acute COVID-19 Syndrome
Interventions: DRUG: Hyperbaric oxygen|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AttraX® Putty vs. Autograft in XLIF®
Status: COMPLETED
Conditions: Degenerative Conditions of the Lumbar Spine
Interventions: BIOLOGICAL: AttraX Putty|OTHER: Iliac Crest Bone Graft (ICBG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Klarity CL, Cylcosporine 0.1%/Loteprednol Etabonate 0.2% Preservative Free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis
Status: UNKNOWN
Conditions: Arteriovenous Fistula Occlusion
Interventions: DRUG: Placebo|DRUG: Ascorbic Acid|DRUG: Cuprimine Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy With Immunotherapy for the Treatment of Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleural Mesothelial Neoplasm
Interventions: OTHER: Immunotherapy|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study
Status: COMPLETED
Conditions: Alternating Hemiplegia
Interventions: OTHER: Review of past medical history, clinical exam, and electroencephalogram, polysomnography and urine samples of melatonin and pupillometry.|OTHER: The patients' parents have to complete the VINELAND II adaptive behavior scales scoring, The Sleep Disturbance Scale for Children (SDSC) and Horne & Ostberg Circadian Typology Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Trametinib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical and Microbiological Assessment of the Efficacy of Chemo-mechanical Caries Removal Versus Conventional Caries Removal Methods in Children: Randomized Controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Chemo-Mechanical Caries Removal
Interventions: OTHER: Chemo-mechanical caries removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study in Patients With Moderate to Severe Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: SHR0302|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation
Status: COMPLETED
Conditions: ARDS|Septic Shock
Interventions: DRUG: Meropenem|PROCEDURE: bronchoscopy|DEVICE: ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Study for Subjects With Congestive Heart Failure
Status: TERMINATED
Conditions: Myocardial Ischemia|Congestive Heart Failure|Cardiovascular Disease
Interventions: BIOLOGICAL: Intramyocardial injection of autologous CD34-positive cells (stem cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of Intravenous TAK-573 as Part of Combination Therapy in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: WITHDRAWN
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: TAK-573|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Brain Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: SL-701; poly-ICLC (polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethyl cellulose)|DRUG: Bevacizumab|DRUG: SL-701 + GM-CSF|DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Bevacizumab in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: bevacizumab|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCI for Hemiparetic Upper Extremities in Patients Due to Stroke
Status: COMPLETED
Conditions: Stroke|Brain Computer Interface
Interventions: DEVICE: Brain Computer Interface/ Functional Electrical Stimulation/ Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of TYNADOTE® in the Treatment of Acetaminophen Overdose
Status: RECRUITING
Conditions: Hepatitis
Interventions: DRUG: TYNADOTE|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ES104 in Patients With Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: ES104|DRUG: ES104|DRUG: ES104
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Management in Endovascular Therapy for Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Thrombectomy|Anesthesia|Conscious Sedation
Interventions: PROCEDURE: General anaesthesia|PROCEDURE: Conscious Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: GI-4000|BIOLOGICAL: haNK for infusion|BIOLOGICAL: avelumab|BIOLOGICAL: bevacizumab|DRUG: Capecitabine|DRUG: Cyclophosphamide|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: nab-Paclitaxel|DRUG: lovaza|DRUG: Oxaliplatin|PROCEDURE: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Immunogenicity, Safety and Tolerability of CSL412 in Elderly Participants
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL412|BIOLOGICAL: Inactivated trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Treatment of Androgenetic Alopecia in Men for 24 Weeks
Status: ACTIVE_NOT_RECRUITING
Conditions: Alopecia
Interventions: DRUG: Minoxidil Topical Foam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ES014 in Patients With Locally Advanced or Metastatic Solid Tumours
Status: RECRUITING
Conditions: Solid Tumor|Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: ES014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Cholecalciferol in Treating Patients Receiving Combination Chemotherapy and Bevacizumab as First-Line Therapy For Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: leucovorin calcium|BIOLOGICAL: bevacizumab|DIETARY_SUPPLEMENT: cholecalciferol|DRUG: fluorouracil|DRUG: oxaliplatin|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inulin-type Fructans on Constipated Children.
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: OraftiR inulin-type fructans|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of YouControl-AFib, a mHealth Application for Persons With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: YouControl-A-Fib mHealth Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Noninferiority Clinical Trial With Laryngeal Mask and Endotracheal Tube
Status: UNKNOWN
Conditions: Laryngospasm|Bradycardia
Interventions: DEVICE: Airway laryngeal mask classic|DEVICE: endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: OTHER: ALK analysis on CTCs detected by ISET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC