pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers
Status: COMPLETED
Conditions: Contraception|Menopause
Interventions: DRUG: 5 mg E4 single-dose|DRUG: 15 mg E4 single-dose|DRUG: 45 mg E4 single-dose|DRUG: 15 mg E4 multiple-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Fixed Dose Versus Single Entities of Dolutegravir and Lamivudine
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Dolutegravir|DRUG: Lamivudine|DRUG: Dolutegravir + Lamivudine FDC Formulation 1|DRUG: Dolutegravir + Lamivudine FDC Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Tranexamic Acid Plus Sublingual Misoprostol in Atonic Postpartum Hemorrhage
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: misoprostol|DRUG: Carbetocin|DRUG: TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preservation and Expansion of T-cell Subsets Following HAART De-intensification to Atazanavir/Ritonavir (ATV/r)
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Early Initiation of Highly Active Anti-Retroviral Therapy|PROCEDURE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MUscle Side-Effects of Atorvastatin in Coronary Patients
Status: COMPLETED
Conditions: Statin Adverse Reaction
Interventions: DRUG: Atorvastatin 40mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Direct Information to At-risk Relatives
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Breast Cancer|Familial Colorectal Cancer|Hereditary Breast and Ovarian Cancer Syndrome|Hereditary Breast Cancer|Lynch Syndrome
Interventions: OTHER: Standard care encouraging family-mediated disclosure of hereditary cancer risk|OTHER: Offer of health-care assisted disclosure by sending direct letters to at-risk relatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase 1 Study of E2022 Tape Formulation for Different Application Sites and Intervals in Japanese Healthy Elderly Males
Status: COMPLETED
Conditions: Healthy Elderly Male
Interventions: DRUG: E2022 Tape Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anthocyanin-rich Blackcurrant and Vascular Function
Status: COMPLETED
Conditions: Vascular Stiffness|Inflammation
Interventions: OTHER: Beverage: Spray dried blackcurrant powder dissolved in water|OTHER: Beverage: Placebo (sucrose, glucose, fructose, maltodextrin, malic acid, citric acid, vitamin C, artificial blackcurrant flavouring and low-nitrate water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: iHIVARNA Clinical Trial in HIV Infected Individuals
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: iHIVARNA-01|BIOLOGICAL: TriMix|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Selected Constituents in the Exhaled Breath Samples
Status: COMPLETED
Conditions: Electronic Cigarette Use|Cigarette Use, Electronic|Tobacco Use|Tobacco Smoking
Interventions: OTHER: JUUL ENDS 5% Virginia Tobacco|OTHER: JUUL 3% Virginia Tobacco ENDS|OTHER: JUUL 5% Mint ENDS|OTHER: JUUL 3% Mint ENDS|OTHER: JUUL 5% Menthol ENDS|OTHER: JUUL 3% Menthol ENDS|OTHER: JUUL 5% Mango ENDS|OTHER: JUUL 3% Mango ENDS|OTHER: US Cigarette, Non-menthol - Marlboro Gold King Size|OTHER: US Cigarette, Menthol - Newport King Size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PembRolIzuMab and Stereotactic Body Radiotherapy In Metastatic Non-small-cell lunG Cancer Patients
Status: TERMINATED
Conditions: Metastatic Non-small-cell lunG Cancer
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT) 30 Gy 3 fractions (#)|RADIATION: Stereotactic Body Radiotherapy (SBRT) 54 Gy 3 fractions (#)|RADIATION: Stereotactic Body Radiotherapy (SBRT) dosed at the maximum tolerated dose|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED95 of Lidocaine 1.0% for Filling the Adductor Canal
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Adductor canal block with lidocaine 1%|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of CV8102 Alone and in Combination With a Rabies Virus Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: CV8102|BIOLOGICAL: Rabipur|BIOLOGICAL: CV8102 + Rabipur
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pivotal Bioequivalence Study Between Fluticasone Propionate 500 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 500/50 Inhalation Powder/GSK in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluticasone propionate 500 mcg and salmeterol xinafoate 50 mcg/Respirent|DRUG: ADVAIR DISKUS® 500/50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Practice-based Trial of Blood Pressure Control in African Americans
Status: COMPLETED
Conditions: Hypertension|Physical Activity|Diet|Medication Adherence
Interventions: BEHAVIORAL: Therapeutic Lifestyle Changes (MINT-TLC)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbidopa/Levodopa/Entacapone Versus Immediate Release (IR) Carbidopa/Levodopa on Non-motor Symptoms in Patients With Idiopathic Parkinson's Disease and Demonstrating Non-motor Symptoms of Wearing Off
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Carbidopa/levodopa/entacapone|DRUG: Immediate release carbidopa/levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Post-thyroidectomy Neck Stretching Exercises on Improving Short Term Quality of Life
Status: UNKNOWN
Conditions: Thyroidectomy
Interventions: OTHER: Stretching and Mobility exercises for neck and shoulder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Well Being and Rehabilitation in Chronically Ill Patients: Structured Patient Education and Physical Exercise
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Heart Failure|Stroke
Interventions: BEHAVIORAL: Self management education programme|BEHAVIORAL: exercise only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sedative Premedication in Coronary Angiography
Status: UNKNOWN
Conditions: Coronary Angiography|Sedative Premedication
Interventions: DRUG: Alprazolam 0.5 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transorbital Ultrasound of Optic Nerve Sheath Diameter Between Healthy Pregnant Women and Those With Severe Preeclampsia.
Status: COMPLETED
Conditions: Preeclampsia Severe
Interventions: PROCEDURE: Transorbital ultrasound of the optic nerve sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Adding Lubiprostone to Standard Large-Volume PEG-ELS on The Quality of Inpatient Colonoscopy Preparation
Status: WITHDRAWN
Conditions: Colonoscopy Preparation
Interventions: DRUG: PEG-ELS current standard of care|DRUG: PEG-ELS current standard of care plus Lubiprostone 24 microgram Oral Cap (x2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Phase 2/3 Multi-Center Study of SM-88 in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: SM-88 used with MPS (methoxsalen, phenytoin, sirolimus)|DRUG: Capecitabine, Gemcitabine, and 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AAT-App Outpatient Trial
Status: COMPLETED
Conditions: Alcohol Use Disorder (AUD)
Interventions: BEHAVIORAL: AAT-App|BEHAVIORAL: Minimal AAT-App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical Efficacy of Autologous Adipose Tissue Derived ADSCSs in Treatment of Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Autologous adipose tissue derived stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-VRD Followed by Lenalidomide Maintenance in Patients With Waldenstrom's Macroglobulinemia
Status: RECRUITING
Conditions: Waldenström's Macroglobulinemia
Interventions: DRUG: Lenalidomide, Bortezomib, Rituximab, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Clinical Study of Severe Hemophilia B Treatment With KL001
Status: NOT_YET_RECRUITING
Conditions: Hemophilia B Without Inhibitor
Interventions: DRUG: Low dose KL001|DRUG: Middle dose KL001|DRUG: High dose KL001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Education and Text Messages on Cardiovascular Disease Risk Factors Awareness Knowledge and Quality of Life
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Health Belief Model Based Cardiovascular Disease Risk Factor Prevention Education|BEHAVIORAL: Reminder Short Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of White Spot Lesion Development Using 3 Orthodontic Adhesive Systems
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: COMBINATION_PRODUCT: Adhesive bonding systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Water Bolus Volumes During Continuous Exercise in Heat
Status: COMPLETED
Conditions: Dehydration (Physiology)|Hyperthermia
Interventions: OTHER: Hydration protocol - 237 mL water bolus|OTHER: Hydration protocol - 500 mL water bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial Evaluating a 7-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: 7-pneumococcal conjugate vaccine (7vPnC)|BIOLOGICAL: diphtheria, tetanus, and acellular pertussis vaccine (DTaP)|BIOLOGICAL: DTaP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of Efficacy and Safety of an Intense Pulsed Light Device to Treat Dry Eye Disease"
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Disease
Interventions: DEVICE: Intense pulsed light with C.STIM device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sticker Pad Containing Essential Oil in Volunteer With High Blood Pressure
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: DEVICE: Sticker pads containing lavender and ylang ylang oil|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Centers Empowerment
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Narrative videos|BEHAVIORAL: A Fitbit activity tracker|OTHER: Daily text message|OTHER: Monthly Zoom meeting|OTHER: Website access|OTHER: Printed materials|BEHAVIORAL: Printed materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
Status: RECRUITING
Conditions: Pain|Hypoxia|Hypercapnia|Apnea
Interventions: OTHER: Voluntary apnoea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Naftin 1% Cream in Adolescent Subjects With Tinea Cruris
Status: COMPLETED
Conditions: Tinea Cruris|Jock Itch
Interventions: DRUG: Naftin 1% Cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte)
Status: UNKNOWN
Conditions: Osteoarthritis|Traumatic Arthritis
Interventions: DEVICE: Chondron Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Nitazoxanide for the Treatment of Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Enterocolitis|Pseudomembranous Colitis
Interventions: DRUG: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial to Reduce Secondhand Smoke Exposure at Homes in Armenia
Status: COMPLETED
Conditions: Tobacco Use and Smoking Behavior
Interventions: BEHAVIORAL: in-person counseling|DEVICE: Demonstration of PM2.5 Pollution|BEHAVIORAL: Follow-up Counseling Calls|BEHAVIORAL: Printed material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel as First-Line Therapy in Participants With High-Risk Large B-Cell Lymphoma
Status: COMPLETED
Conditions: B-cell Lymphoma
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: SAR444656 (KT-474)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI
Status: RECRUITING
Conditions: STEMI - ST Elevation Myocardial Infarction|NSTEMI - Non-ST Segment Elevation MI
Interventions: DRUG: Evolocumab 140 MG/ML|DRUG: Standard of care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Surgery With Sorafenib for Hepatic Celluler Cancer With Portal Vein Tumor Thrombosis
Status: UNKNOWN
Conditions: Portal Vein Tumor Thrombus
Interventions: DRUG: Sorafenib|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple-Dose Research Study on Safety Evaluation of the GD Antrodia Camphorata in 30 Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: GD Antrodia camphorata
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders
Status: UNKNOWN
Conditions: Chediak-Higashi Syndrome|Graft Versus Host Disease|X-Linked Lymphoproliferative Syndrome|Familial Erythrophagocytic Lymphohistiocytosis|Hemophagocytic Lymphohistiocytosis|Virus-Associated Hemophagocytic Syndrome
Interventions: DRUG: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: etoposide|DRUG: filgrastim|DRUG: methotrexate|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Provider's Feedback on Physical Activity Surveillance Using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Physical Activity
Interventions: OTHER: Receving feedback|OTHER: No regular feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fc factOrs and Real-World hemophiliA Patient-ReporteD Outcomes
Status: TERMINATED
Conditions: Hemophilia A|Hemophilia B
Interventions: BIOLOGICAL: rFVIIIFc|BIOLOGICAL: rFIXFc|DRUG: non-Fc FVIII replacement products|DRUG: non-Fc FIX replacement products
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain Activity and Oxygenation Inflammatory Bowel Disease (IBD) Patients
Status: RECRUITING
Conditions: IBD|Maladaptive Behavior Associated With Physical Illness
Interventions: BEHAVIORAL: Quality of life questionnaires|DEVICE: NIRS|OTHER: Stool Collection|OTHER: Blood and urine collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Investigational Magnetic Resonance Imaging and Post-Processing Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: MRI Imaging
Interventions: DIAGNOSTIC_TEST: MRI Scan - in addition to standard of care|DIAGNOSTIC_TEST: MRI Scan - not in addition to standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Niclosamide for Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Niclosamide|DRUG: Placebo|OTHER: Telehealth monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate Neoadjuvant Nivolumab (OPDIVO®) in Combination With Platinum-Based Chemotherapy in Non-Metastatic Non-Small Cell Lung Cancer Participants in Germany
Status: RECRUITING
Conditions: Resectable Non-small Cell Lung Cancer
Interventions: DRUG: Neoadjuvant nivolumab in combination with platinum-based chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.
Status: COMPLETED
Conditions: Neurotrophic Keratitis|Keratitis|Corneal Ulcer
Interventions: DRUG: rhNGF 10 μg/ml|DRUG: rhNGF 20 μg/ml|OTHER: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHAPE of Portal Hypertension in Children
Status: RECRUITING
Conditions: Hypertension, Portal
Interventions: DRUG: SHAPE measurement using the ultrasound contrast agent Sonazoid (perfluorobutane microbubbles)|DRUG: SHAPE measurement using the ultrasound contrast agent Lumason (sulfur hexafluoride lipid-type A microspheres)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Tissue Plasminogen Activator in the Clearance of Chronic Subdural Hematomas
Status: RECRUITING
Conditions: Hematoma, Subdural|Fibrinolytic; Hemorrhage
Interventions: DRUG: Tissue Plasminogen Activator|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Metabolic Effects of Zinc-Amino Acid (ZnAA) Versus Zinc Gluconate
Status: RECRUITING
Conditions: Response of Fatty Acid Desaturation to Zinc Intake
Interventions: DIETARY_SUPPLEMENT: 30 mg Zn Amino Acid daily for 13 days|DIETARY_SUPPLEMENT: 30 mg Zn Gluconate daily for 13 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of BEVESPI AEROSPHERE ® Therapy on Exercise Tolerance in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Glycopyrrolate / Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety of Replenine®-VF, Replenine® or Other Factor IX in Haemophilia B
Status: COMPLETED
Conditions: Haemophilia B
Interventions: BIOLOGICAL: Replenine®-VF (High Purity Factor IX)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Conservative Intervention of Femoroacetabular Impingement Syndrome
Status: WITHDRAWN
Conditions: Femoroacetabular Impingement
Interventions: OTHER: Manual therapy|OTHER: Exercise|OTHER: Education and advice|OTHER: Supervised neglect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Feasibility of Wysa in Hindi
Status: RECRUITING
Conditions: Mental Health Issue|Diabetes Distress
Interventions: BEHAVIORAL: Wysa in Hindi|BEHAVIORAL: Individual and group sessions on topics like motivation, coping, wellbeing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Psychoeducational Course for Suicide Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicide Prevention|Suicide Threat|Self Efficacy|Stress, Psychological|Psychiatric Emergency|Psychiatric Disorder
Interventions: OTHER: Psychoeducational Course for Suicide Prevention|OTHER: Individual therapy session|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences
Status: RECRUITING
Conditions: Skin Toxicity
Interventions: OTHER: Complementary and alternative medicine (CAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prebiotic EffecT InfanTs
Status: RECRUITING
Conditions: Infant Development|Healthy|Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin
Status: COMPLETED
Conditions: Actinic Keratosis|Photo-aged Skin
Interventions: DRUG: Ingenol Mebutate (Picato®) 0.015% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rimonabant|DRUG: Placebo (for Rimonabant)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of an 8 Week Niaspan Treatment in Patients With Abdominal Obesity and Mixed Dyslipidemia
Status: COMPLETED
Conditions: Insulin Sensitivity|Lipoproteins Metabolism|Non Esterified Fatty Acid Kinetics|Lipid Profile
Interventions: DRUG: Extended-release nicotinic acid versus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pyrotinib Combined With Trastuzumab,Dalpiciclib and Letrozole for HR+/HER2+ Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: pyrotinib combined with trastuzumab, dalpiciclib and letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Free Venlafaxine Treatment for Marijuana Addiction and Depression - 1
Status: COMPLETED
Conditions: Depression|Marijuana Abuse
Interventions: DRUG: Venlafaxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis Use Among 15 to 17 Year Old Young Men Who Have Sex With Men (YMSM)
Status: COMPLETED
Conditions: HIV Infection
Interventions: BEHAVIORAL: PCC|DRUG: Emtricitabine/tenofovir (FTC/TDF (Truvada®))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GM-CSF in Patients With Pulmonary Alveolar Proteinosis
Status: TERMINATED
Conditions: Pulmonary Alveolar Proteinosis
Interventions: DRUG: GM-CSF (granulocyte-macrophage colony-stimulating factor, sargramostim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of RX-10100 to Treat Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction (ED)
Interventions: DRUG: Placebo|DRUG: RX-10100 5mg|DRUG: RX-10100 10mg|DRUG: RX-10100 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentre Registry of Treatments and Outcomes in Patients With Chronic Lymphocytic Leukaemia (CLL) Or Indolent Non Hodgkin's Lymphoma (iNHL)
Status: TERMINATED
Conditions: Indolent Non Hodgkin's Lymphoma (iNHL)|Chronic Lymphocytic Leukaemia (CLL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: ALK Grass tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of KLS-0611 in Patients With Dry Eye Syndromes
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Placebo|DRUG: KLS-0611
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST
Status: TERMINATED
Conditions: Connective Tissue Disease-Associated Pulmonary Arterial Hypertension
Interventions: DRUG: Placebo capsules|DRUG: Bardoxolone methyl capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Behavioral activation (BA)|OTHER: Regular care within primary or secondary mental health care for children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Cardiorespiratory Fitness and Body Composition on Resting and Post-exercise Indices of Vascular Health in Young Adults
Status: COMPLETED
Conditions: Endothelial Dysfunction|Arterial Stiffness
Interventions: OTHER: Acute submaximal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Eribullin or Eribulin Combined With Anlotinib in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Alvocidib, and Rituximab in Treating Patients With High Risk B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage I Small Lymphocytic Lymphoma|Stage II Chronic Lymphocytic Leukemia|Stage II Small Lymphocytic Lymphoma|Stage III Chronic Lymphocytic Leukemia|Stage III Small Lymphocytic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Small Lymphocytic Lymphoma
Interventions: DRUG: Alvocidib Hydrochloride|DRUG: Cyclophosphamide|OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F17464 in Acute Schizophrenia Trial
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: F17464|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Biospecimen collection|PROCEDURE: Biospecimen collection|PROCEDURE: Biospecimen collection|PROCEDURE: Biospecimen collection|PROCEDURE: Pulmonary Function Test|PROCEDURE: Computed Tomography (CT)|OTHER: Laboratory Biomarker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Prizvalve Pro™ transcatheter aortic valve system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Lisdexamfetamine dimesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound Study of the Airway to Predict Endotracheal Tube Size in Anesthetized Pediatric Patients
Status: COMPLETED
Conditions: Pediatric General Anesthesia With Endotracheal Tube
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Ombrabulin in Patients With Platinum-Sensitive Recurrent Ovarian Cancer Treated With Carboplatin/Paclitaxel
Status: COMPLETED
Conditions: Ovarian Cancer Recurrent
Interventions: DRUG: Ombrabulin (AVE8062)|DRUG: Placebo|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Biomarker Study of Palbociclib + Fulvestrant for Second, and Third Line of Postmenopausal Women With hr+/her2- Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|HR+/HER2-negative Breast Cancer|Metastasis
Interventions: DRUG: Fulvestrant + palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
Status: RECRUITING
Conditions: Transcranial Alternating Current Stimulation|Non-suicidal Self-injury
Interventions: DEVICE: High-Definition Transcranial Alternating Current Stimulation (HD-tACS)|DEVICE: sham High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug in Patients With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (0431-028)(COMPLETED)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Chronic Renal Insufficiency
Interventions: DRUG: sitagliptin|DRUG: Placebo to Sitagliptin|DRUG: glipizide|DRUG: Placebo to glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients
Status: COMPLETED
Conditions: Wounds and Injuries|Rib Fractures
Interventions: DRUG: Ketamine|DRUG: Placebo|PROCEDURE: Intercostal Nerve Block|DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Pantoprazole|DRUG: Methocarbamol|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Whey and Collagen on FFM, Muscle Strength and Wound Healing in Elderly Surgical Patients
Status: COMPLETED
Conditions: Hip Arthritis|Sarcopenia|Knee Arthritis
Interventions: DIETARY_SUPPLEMENT: Whey protein and Collagen supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma Metastases
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: PROCEDURE: PET diagnostic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Trial of Gemcitabine Containing Regimens As Preoperative Chemotherapy in Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non Small Cell Lung
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hydrotherapy and Land-based Rehabilitation Program Combined With Ankle Taping in Athletes With Chronic Ankle Instability
Status: COMPLETED
Conditions: Sports Rehabilitation Program|Hydrotherapy|Ankle Instability
Interventions: PROCEDURE: hydrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expecting Mother's Study of Consumption or Avoidance of Peanut and Egg
Status: NOT_YET_RECRUITING
Conditions: Allergy and Immunology|Peanut and Nut Allergy|Egg Allergy|Food Allergy in Infants|Food Allergy Peanut
Interventions: BEHAVIORAL: Avoidance|BEHAVIORAL: Consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Haematological Malignancies
Interventions: DRUG: AZD4573|DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Treatment for Acute ACL Tear
Status: COMPLETED
Conditions: Anterior Cruciate Ligament (ACL) Tears
Interventions: DRUG: Kenalog or placebo|DRUG: Kenalog then Placebo|DRUG: Kenalog|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: a BavaRiAn eValuatiOn of Dorsal Root Ganglion (DRG) Stimulation for the Treatment for Chronic Post Surgical Pain of the Groin
Status: TERMINATED
Conditions: Post Surgical Groin Pain
Interventions: DEVICE: Implantation with the commercially available Axium neurostimulator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Manual Therapy and Virtual Reality Supported in Patient With Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Manual therapy|OTHER: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of HSG4112 in Overweight and Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: HSG4112|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy for Head and Neck Tumors
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck|Nasopharyngeal Carcinoma|Salivary Gland Cancer|Head and Neck Sarcoma|Paraganglioma of Head and Neck|Chordoma of Head and Neck|Chondrosarcoma of Head and Neck|Angiofibroma of Head and Neck
Interventions: RADIATION: stereotactic body radiotherapy|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nebulizers vs Metered-Dose Inhalers With Spacer Device For Treatment Of Childhood Wheeze
Status: RECRUITING
Conditions: Childhood Asthma With Acute Exacerbation
Interventions: DEVICE: Metered Dose Inhaler With Spacer Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exercise to Reduce Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Gastrointestinal Cancer|Colorectal Cancer|Pancreatic Cancer|Gastric Cancer|Stomach Cancer|Esophageal Cancer
Interventions: BEHAVIORAL: MI-Walk Intervention|BEHAVIORAL: Physical Activity Education Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of Collagen Cross Linking in Progressive Mild and Moderate Keratoconus
Status: UNKNOWN
Conditions: Cornea Degeneration|Progressive Keratoconus
Interventions: PROCEDURE: Collagen Cross Linking with Riboflavin and UVA light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin NPH|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Comparing Overall Improvement of Patients With Spondyloarthritis Treated With Jitongning Tablets and Placebo
Status: RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Jitongning tablets|DRUG: a simulated agent of Jitongning tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Tirofiban|DRUG: Tirofiban simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Autosuggestion for Quality of Life of Geriatric Patients
Status: COMPLETED
Conditions: Quality of Life for Geriatric Patients.
Interventions: BEHAVIORAL: Autosuggestion for 30 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexamethasone Nanoparticles Eye Drops in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone nanoparticles eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Leukemia, Myelomonocytic, Chronic|Patient Preference
Interventions: DRUG: Subcutaneous azacitidine|DRUG: Oral decitabine/cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Durvalumab+Neoadjuvant Chemotherapy for High-risk Urothelial Carcinoma of the Upper Urinary Tract
Status: RECRUITING
Conditions: Urothelial Carcinoma|Cancer
Interventions: DRUG: Patients receiving neoadjuvant therapy before radical nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 Weeks in Participants With Chronic HCV Infection and Child-Pugh-Turcotte Class C Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mothers' Parenting Satisfaction and Parenting Self-efficacy: An Evaluation of a Infant Calming Method
Status: COMPLETED
Conditions: Parenting Satisfaction|Parenting Self-efficacy
Interventions: BEHAVIORAL: The 5 S's infant calming intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia
Status: COMPLETED
Conditions: Proctalgia
Interventions: DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginosis
Interventions: DRUG: 750 mg metronidazole/ 200 mg miconazole vaginal suppository|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy Induced Peripheral Neuropathy (CIPN) and Lymphoma Longitudinal Follow-up and Prognostic Factors
Status: RECRUITING
Conditions: Lymphoma|Peripheral Neuropathy
Interventions: OTHER: Clinical scales of CIPN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC