pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial Comparing the Efficacy and Safety of Exubera® and Lantus®
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine (Lantus®)|DRUG: Inhaled Human Insulin (Exubera®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: bomedemstat|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Large B-cell, Diffuse|Lymphoma, Follicular
Interventions: DRUG: TAK-659|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery
Status: UNKNOWN
Conditions: Knee Disease|Delirium
Interventions: PROCEDURE: ultrasound-guided high fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Eprosartan and Eprosartan Mesylate on Blood Pressure in Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Eprosartan|DRUG: Eprosartan Mesylate|DRUG: Placebo Eprosartan mesylate|DRUG: Placebo Eprosartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Guided Self-help CBT-E vs Online G-CBT-E for Binge Eating Behavior
Status: NOT_YET_RECRUITING
Conditions: Feeding and Eating Disorders
Interventions: BEHAVIORAL: web-based guided self-help Enhanced Cognitive Behavioral therapy|BEHAVIORAL: online Enhanced Cognitive Behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crystalloids Versus Colloids During Surgery
Status: COMPLETED
Conditions: Fluid Overload|Postoperative Complications
Interventions: DRUG: Lactated Ringer's Solution|DRUG: Hydroxyethylstarch 6% 130/0.4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Carbohydrate Drink on Speed, Agility and Power in School Going Children
Status: COMPLETED
Conditions: Growth and Development
Interventions: DIETARY_SUPPLEMENT: Carbohydrate beverage powder|DIETARY_SUPPLEMENT: Calorie matched beverage powder|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Compare the Bioavailability Intranasal Administration of 200 and 400 µg or 400 µg Alone of OPTINOSE™ FLUTICASONE With 440 µg of Flovent® HFA (Fluticasone Propionate) Inhalation Aerosol (Part 2)
Status: COMPLETED
Conditions: Mild to Moderate Asthma
Interventions: DRUG: Flovent HFA|DRUG: OPTINOSE™ FLUTICASONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ARRY-614 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: ARRY-614, p38/Tie2 inhibitor; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethnic Microaggressions and Smoking Behaviors Among Latinx Adults
Status: RECRUITING
Conditions: Smoking|Discrimination, Racial
Interventions: BEHAVIORAL: Microaggression Recall and Relapse Analogue Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Silver Diamine Fluoride|DRUG: Chlorhexidine|PROCEDURE: Atraumatic Restorative Treatment without Disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PECs for Implantable Cardiac Electronic Device Insertion
Status: COMPLETED
Conditions: Cardiac Implantable Electronic Device|Nerve Block|Anesthesia|Analgesia
Interventions: OTHER: Pectoral Nerve (PECs) block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can we Safely Have Our Patients Eat With Cardiac Catheterization - Nix Or alloW: The CHOW NOW Study
Status: COMPLETED
Conditions: Chest Pain
Interventions: OTHER: No Fasting prior to catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Butyrate on Inflammation and Albuminuria in Patients With Albuminuria, Type 1 Diabetes and Intestinal Inflammation
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Albuminuria
Interventions: DIETARY_SUPPLEMENT: Sodium butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Naltrexone High Dose|DRUG: Naltrexone Low Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Fenestration With and Without Clipping in Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: PROCEDURE: Fenestration|PROCEDURE: Fenestration and clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Is Verapamil In TransRadial Interventions OmittabLe?
Status: COMPLETED
Conditions: Coronary Disease|Verapamil Toxicity
Interventions: DRUG: Verapamil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Wrist Extension Dynasplint (WED) Distal Radius Fracture
Status: UNKNOWN
Conditions: Distal Radius Fracture|Wrist Contracture
Interventions: DEVICE: Wrist Extension Dynasplint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apnoeic Oxygenation by Nasal Cannula During Airway Management in Children Undergoing General Anaesthesia.
Status: COMPLETED
Conditions: Apnoeic Oxygenation
Interventions: DEVICE: Apnoeic oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PIEB Compared With CEI on Breakthrough Pain in Multiparous Women
Status: NOT_YET_RECRUITING
Conditions: Breakthrough Pain
Interventions: DRUG: programmed intermittent Bolus epidural analgesia|DRUG: continuous epidural infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Subjects
Interventions: DRUG: T Leuprolide Injectable Emulsion|DRUG: Leuprorelin Acetate Microspheres for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine Monotherapy for Executive Dysfunction and ADHD
Status: WITHDRAWN
Conditions: ADHD|Executive Function Deficits (EFD's)
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study
Status: RECRUITING
Conditions: Neoplasm Malignant|Colon Cancer Stage 4
Interventions: DRUG: FOLFOXIRI Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Roxadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.
Status: COMPLETED
Conditions: LMA Vs I Gel
Interventions: DEVICE: Laryngeal Mask Airway|DEVICE: I gel Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rehabkompassen® - a Patient-centered Digital Follow-up Tool in the Post-stroke Continuum of Care
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: a usual follow-up with Rehabkompassen®|OTHER: a usual follow-up with Post-Stroke Checklist, i.e. without Rehabkompassen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical Exploration of Adeno-associated Virus (AAV) Expressing Human Acid Alpha- Glucosidase (GAA) Gene Therapy for Patients With Infantile-onset Pompe Disease
Status: RECRUITING
Conditions: Infantile-onset Pompe Disease
Interventions: BIOLOGICAL: Genetic: GC301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: MIR 19 ®|COMBINATION_PRODUCT: Standard COVID-19 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in Participants With Active Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: Guselkumab Dose 1|DRUG: Placebo|DRUG: Guselkumab Dose 2|DRUG: Standard-of-care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Incision Study - Closure of Skin Incisions in Gynecological Cancer Surgery
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Caprosyn subcuticular sutures.|OTHER: Monocryl subcuticular sutures.|OTHER: Skin staples;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study Evalutating the Pharmacokinetics (PK) and Safety of a Single Dose of Desvenlafaxine Sustained Release (DVS SR)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Desvenlafaxine Sustained Release (DVS SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Douyin in Patients With Bone and Soft Tissue Malignant Tumors During Perichemotherapy
Status: NOT_YET_RECRUITING
Conditions: Malignant Tumor|Chemotherapy
Interventions: OTHER: Tik Tok
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dragon Ambient eXperience (DAX) Copilot Evaluation
Status: COMPLETED
Conditions: Automated Clinical Documentation
Interventions: OTHER: Dragon Ambient eXperience (DAX) Copilot
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness
Status: RECRUITING
Conditions: Smoking Cessation|Smoking, Tobacco|Mental Illness|Tobacco Use Disorder
Interventions: BEHAVIORAL: Videogame-based physical activity|BEHAVIORAL: sedentary videogame|DRUG: Bupropion|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cervical Restorations Performance Using Modified Universal Adhesive
Status: NOT_YET_RECRUITING
Conditions: Clinical Performance
Interventions: DRUG: Modified universal adhesive|DRUG: Conventional universal adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Crossover Adherence and Acceptability Study Assessing a DPP Capsule for HIV and Pregnancy Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Dual Prevention Pill|DRUG: PrEP tablet and a COC as two separate tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neoadjuvant Anti-PD-1 Immunotherapy on Perioperative Analgesia and Postoperative Delirium
Status: COMPLETED
Conditions: Immunotherapy|Analgesia|NSCLC|Delirium
Interventions: DRUG: neoadjuvant immunotherapy|DRUG: Neoadjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised Trial to Evaluate Toxicity and Efficacy of 1200mg and 1800mg Rifampicin for Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Rifampicin|DRUG: Isoniazid|DRUG: Ethambutol|DRUG: Pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carpal Tunnel Syndrome: Diagnosis and Treatment Trial
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Early Carpal Tunnel Release for Mild or Moderate CTS|OTHER: MR Nerve Imaging for CTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom Management After Breast Cancer Surgery
Status: COMPLETED
Conditions: Neuropathic Pain|Postmastectomy Pain
Interventions: DRUG: Lidoderm patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feeding Tolerance and Growth of Preterm Infants Consuming a Supplement Containing Two Human Milk Oligosaccharides (HMOs)
Status: RECRUITING
Conditions: Premature Infant|Low Birthweight Infant
Interventions: DIETARY_SUPPLEMENT: HMO supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Naldebain for Pain Management After Knee Arthroplasty
Status: COMPLETED
Conditions: Arthropathy of Knee Joint
Interventions: DRUG: Nalbuphine Sebacate (Naldebain)|DRUG: Placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Ga-68-PSMA-11 PET/CT|DRUG: Lu-177-ITG-PSMA-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy
Status: COMPLETED
Conditions: Stage IV Skin Melanoma
Interventions: OTHER: Laboratory Biomarker Analysis|PROCEDURE: Radionuclide Imaging|BIOLOGICAL: Technetium Tc 99 Hydrazinonicotinamide-Tricine-linked Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study of Metronomic Chemotherapy for Locally Advanced HER2-Negative Breast Cancer
Status: TERMINATED
Conditions: Locally Advanced HER2-negative Breast Cancer
Interventions: DRUG: Paclitaxel/doxorubicin/cyclophosphamide|DRUG: Paclitaxel/doxorubicin/cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
Status: TERMINATED
Conditions: Genito Urinary Cancer|Bladder Cancer|Kidney Cancer|Prostate Cancer
Interventions: PROCEDURE: Bone marrow biopsy|PROCEDURE: Tumor biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Medication Dispenser to Improve Care at Home for the Elderly
Status: WITHDRAWN
Conditions: Medication Adherence|Cognitive Impairment
Interventions: DEVICE: SME + Karie Device|OTHER: SME only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduction of Pulmonary Artery Pressure in Patients Subjected to Cardiac Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleeping for Two: RCT of CBT-Insomnia in Pregnancy
Status: COMPLETED
Conditions: Insomnia|Sleep Disturbance
Interventions: OTHER: Cognitive-Behavioural Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Connecting Through Caregiving: Reappraising Intergeneration Relationships
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: Connecting Through Caregiving|OTHER: Basic Skills Building
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: 6 Minute Walk Functional Test|BEHAVIORAL: Behavioral Intervention|OTHER: Survey Administration|BEHAVIORAL: Timed Get Up and Go Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II)
Status: COMPLETED
Conditions: Neoplasms|Breast Neoplasms|Breast Cancer
Interventions: DRUG: AZD8931|DRUG: Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of SINC Feeding Protocol on Weight Gain, Transition to Oral Feeding and the Length of Hospitalization
Status: COMPLETED
Conditions: Feeding; Difficult, Newborn
Interventions: OTHER: SINC Feeding Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 8 vs 4 Sessions Mindfulness-based Programs in a Non-clinical Population
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BEHAVIORAL: standard 8-weeks MBSR|BEHAVIORAL: 4-week shortened MBSR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions
Status: COMPLETED
Conditions: Breast Cancer With Bone Metastasis
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of The Walking Exercise Training Given According to Transtheoretical Model, and Follow-Up on Improving Exercise Behavior and Metabolic Control in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trapezoidal Condylar Plate (TCP) in Treatment of Subcondylar Fracture
Status: UNKNOWN
Conditions: Fracture of Condylar Process
Interventions: DEVICE: trapezoidal condylar plate|DEVICE: two miniplates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia
Status: RECRUITING
Conditions: Avoidant/Restrictive Food Intake Disorder|Dyspepsia|Feeding and Eating Disorders|Cognitive Behavioral Therapy|Appetite Regulation|Functional Dyspepsia|Post-prandial Distress Syndrome|Behavioral Medicine
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of the Glutaminase Inhibitor CB-839 in Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphocytic Leukemia (ALL)
Interventions: DRUG: CB-839|DRUG: CB-Aza
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Avandia (Rosiglitazone)|DRUG: Avanclia (Rosiqlitazone)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Critical Illness|Carbapenem|Pharmacokinetic|Pharmacodynamic|Clinical Outcome|Organ Failure, Multiple|Morality
Interventions: DRUG: Meropenem standard dose|DRUG: Meropenem high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears
Status: WITHDRAWN
Conditions: Rotator Cuff Tear
Interventions: DEVICE: Sterile Spring Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-world Efficacy and Safety of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy in Adult Patients With Cystic Fibrosis (CF)
Status: NOT_YET_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: CFQ-R questionnaire, SNOT-22 questionnaire, fecal elastase measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Letrozole Regimen Co-treatment With Gonadotropin Releasing Hormone Antagonist Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in Poor Responders Undergoing IVF-ET
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: GnRH ant/letrozole|DRUG: GnRH ant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VAC Dressings for Colorectal Resections
Status: UNKNOWN
Conditions: Surgical Site Infection|Wound Complication|Wound Dehiscence|Seroma|Hematoma
Interventions: DEVICE: Incisional Negative Pressure Wound Therapy (iNPWT)|DEVICE: Sterile Gauze Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Ataluren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants
Status: COMPLETED
Conditions: Breast Reconstruction
Interventions: DEVICE: Natrelle(TM) Silicone-Filled Breast Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Combination Therapy With Minocycline for Treatment of Stenotrophomonas Maltophilia Infections
Status: RECRUITING
Conditions: Hospital Infections
Interventions: DRUG: Minocycline|DRUG: Levofloxacin or Cotrimoxazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Neurodynamic Techniques for the Treatment of Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Neurodynamic techniques|OTHER: Exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline and Systemic Inflammation in Hemodialysis Patients
Status: COMPLETED
Conditions: Inflammation|End-stage Renal Disease|Hemodialysis
Interventions: DRUG: Pentoxifylline|DRUG: starch tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery
Status: UNKNOWN
Conditions: Colonic Neoplasms
Interventions: DRUG: Ropivacaine|DRUG: Fentanyl|DRUG: Propofol|DRUG: Isoflurane|DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome
Status: RECRUITING
Conditions: Piriformis Syndrome
Interventions: PROCEDURE: Electrotherapy|PROCEDURE: Active release technique|PROCEDURE: Hold relax technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome
Status: COMPLETED
Conditions: Lennox Gastaut Syndrome (LGS)
Interventions: DRUG: Placebo|DRUG: Soticlestat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thymosin Plus PEG-Interferon in Non-Cirrhotic Hepatitis C Patients Who Did Not Respond to Interferon or Interferon Plus Ribavirin
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C, Chronic
Interventions: DRUG: thymalfasin (thymosin alpha 1) + PEGinterferon alfa-2a|DRUG: placebo + PEGinterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Role of the Right Portal Pedicle and Rouviere's Sulcus as an Anatomic Landmark in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Gallstones|Cholecystitis|Polyps
Interventions: PROCEDURE: Rouviere's sulcus|DEVICE: surgical instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Podiatry Intervention to Reduce Falls in Elderly Care Trial (PIRFECT)
Status: COMPLETED
Conditions: Accidental Falls
Interventions: OTHER: Foot and ankle exercises, foot orthoses, footwear provision|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Minimally invasive non surgical periodontal therapy|PROCEDURE: Conventional subgingival instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients
Status: TERMINATED
Conditions: Advanced Soft Tissue Sarcoma
Interventions: DRUG: Olaratumab|DRUG: Dexrazoxane|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Status: RECRUITING
Conditions: Rib Fractures|Rib Fracture Multiple|Rib; Fracture, With Flail Chest|Pain|Pain, Acute|Pain, Chronic|Trauma|Trauma Injury
Interventions: PROCEDURE: Cryoneurolysis|PROCEDURE: Sham Cryoneurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intermediate-stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: HCC
Interventions: DEVICE: Basic drugs therapy of HCC by TACE|DRUG: Arginine hydrochloride|DRUG: Trimetazidine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in Combination for the Treatment of Overactive Bladder
Status: COMPLETED
Conditions: Urologic Diseases|Urinary Bladder Diseases|Urological Manifestations|Signs and Symptoms|Urinary Bladder, Overactive
Interventions: DRUG: Mirabegron|DRUG: Solifenacin succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Improve Renal Function After Kidney Transplantation
Status: UNKNOWN
Conditions: Delayed Graft Function
Interventions: DRUG: BB3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy
Status: WITHDRAWN
Conditions: Renal Calculi|Postoperative Pain
Interventions: DRUG: liposomal bupivicaine|DRUG: Bupivacaine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Management of Acute Diarrhoeal Disease
Status: COMPLETED
Conditions: Acute Gastroenteritis
Interventions: OTHER: Rapid diagnostics|BIOLOGICAL: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Cervical Cancer
Interventions: OTHER: TopCare: Use of provider knowledge vs. automated system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cognitive Inhibition, Psychosocial Interactions and Suicide Attempt in Elderly
Status: UNKNOWN
Conditions: Suicide
Interventions: BEHAVIORAL: eye tracking|BEHAVIORAL: neuropsychological assessement|BEHAVIORAL: psychiatric assessment|BEHAVIORAL: sociological interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Evaluation Of MP26 Features in Adults
Status: COMPLETED
Conditions: Brain Imaging|Whole Body Imaging
Interventions: DEVICE: Zero Echo Time (ZTE) scan for head attenuation|DEVICE: Q.Static (Q. MRAC) for respiratory motion correction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Gabapentin in the Treatment of Chest Pain and Paresthesia in Patients With Sternotomy
Status: COMPLETED
Conditions: Chest Pain|Paresthesia
Interventions: DRUG: Gabapentin|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient With Any Pathology (According to the Appreciation of the Investigator) Which Could Disturb the Participation in the Study
Status: UNKNOWN
Conditions: Type 1 Diabetes in Children
Interventions: BIOLOGICAL: blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D Treatment of Diabetic Patients With Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Long-term Follow-up Study of Participants Who Received an Allogeneic CAR T-Cell Product
Status: RECRUITING
Conditions: Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product (PBCAR) in a Precision BioSciences, Inc., Clinical Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Disease(CKD)|Uncontrolled Hypertension
Interventions: DRUG: Antihypertensive algorithm|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Ningmitai Capsule on Promoting the Passage of Residual Fragments After Ureteroscopic Lithotripsy
Status: COMPLETED
Conditions: Ureteral Calculi
Interventions: DRUG: Control group|DRUG: Ningmitai capsule|DRUG: Combined group (Ningmitai plus tamsulosin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: I-BiT - Evaluation of a Novel Binocular Treatment System (I-BiTTM) in Children With Amblyopia
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: I-BiTTM game|DEVICE: Non-I-BiTTM game|DEVICE: I-BiTTM DVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega-3 Fatty Acid (OMACOR) on the Low-density Lipoprotein (LDL) Sub-fraction in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Hypercholesterolemia|Hypertriglyceridemia
Interventions: DRUG: Omega-3 acid 4 grams per day|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: [18F]F-FAPI PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: CPT-11|DRUG: Paclitaxel|DRUG: Vinorelbine Tartrate|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Delta9-tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R33 Study
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Placebo capsule|DRUG: Dronabinol 7.5 milligram oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT
Status: TERMINATED
Conditions: Assisted Reproductive Technology|Antibiotic Prophylaxis|Embryo Transfer
Interventions: OTHER: Withholding antibiotic prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rasagiline and Apathy in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calf Muscle Perfusion in Patients With Intermittent Claudication by Non-invasive MSOT
Status: UNKNOWN
Conditions: Peripheral Vascular Diseases|Peripheral Arterial Disease|Intermittent Claudication
Interventions: DEVICE: Multispectral Optoacoustic Tomography (MSOT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Maternal Mental Health and Wellbeing in Neonatal Intensive Care
Status: COMPLETED
Conditions: Depressive Symptoms|Anxiety|Post-traumatic Stress Symptoms
Interventions: BEHAVIORAL: Mindfulness Program|BEHAVIORAL: Infant Health Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab|DRUG: methotrexate|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Safety of Escalating Doses of PRO131921 in Patients With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: PRO131921
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Embodiment for Upper Limb Amputees
Status: NOT_YET_RECRUITING
Conditions: Amputation
Interventions: DEVICE: Prosthetic hand|PROCEDURE: Peripheral Nerve Interface
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Neurodynamic Exercises and Education Program Applied With Virtual Reality Assisted Telerehabilitation Method in Conservative Treatment of Carpal Tunnel Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Carpal Tunnel Syndrome|Peripheral Neuropathy|Median Nerve Entrapment
Interventions: BEHAVIORAL: Virtual Reality Assisted Neurodynamic Exercises and Patient Education with Telerehabilitation Method|BEHAVIORAL: Neurodynamic Exercises and Patient Education with Traditional Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis
Status: SUSPENDED
Conditions: ANCA Associated Vasculitis
Interventions: DEVICE: ENUMERATION OF CD5+ B Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Cultured Bone Marrow Derived Allogenic MSCs in AMI
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Stem cell|DRUG: Plasmalyte A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia
Status: RECRUITING
Conditions: Recurrent Hairy Cell Leukemia|Recurrent Hairy Cell Leukemia Variant
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Cocoa Supplementation and Elite Soccer Players
Status: COMPLETED
Conditions: Dyslipidemias|Fatty Acid; Metabolic Disorder
Interventions: DIETARY_SUPPLEMENT: dark chocolate|DIETARY_SUPPLEMENT: White chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Eslicarbazepine acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures
Status: UNKNOWN
Conditions: Hip Fractures|Surgical Blood Loss
Interventions: DRUG: Tranexamic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNFα-Inhibitor Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriatic Arthritis
Interventions: BIOLOGICAL: Secukinumab|BIOLOGICAL: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining a Wheelchair Exercise-training Intervention for Persons With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Seated Physical activity INtervention for persons with MS, "SPIN" program- Intervention Condition|BEHAVIORAL: WEllness for Longevity Living with MS (WELL)- Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of TQH3821 Tablets in the Treatment of Treated Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: TQH3821 tablets 200 mg|DRUG: TQH3821 tablets matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of An Adjuvanted Inactivated H7N9 Influenza Vaccine
Status: UNKNOWN
Conditions: H7N9 Influenza
Interventions: BIOLOGICAL: 15μg H7N9 Vaccine|BIOLOGICAL: Aluminum Hydroxide Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy
Status: COMPLETED
Conditions: Lung Diseases|Diagnosis|Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vadadustat in Hemodialysis Participants With Anemia Switching From Epoetin Alfa
Status: COMPLETED
Conditions: Anemia|Dialysis-dependent Chronic Kidney Disease
Interventions: DRUG: Vadadustat|DRUG: Epoetin Alfa|DRUG: Vadadustat TIW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT