pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Low-pressure Pneumoperitoneum on Pain and Inflammation Post Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pneumoperitoneum|Pain|Inflammation
Interventions: PROCEDURE: low-pressure pneumoperitoneum|PROCEDURE: standard-pressure pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Benzocaine 20% Topical Anesthetic and no Topical Agent on Pain Perception During Intra-oral Injections
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: No topical anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection
Status: COMPLETED
Conditions: Acute HIV Infection
Interventions: DRUG: Vorinostat|DRUG: Hydroxychloroquine|DRUG: Maraviroc|DRUG: Tenofovir|DRUG: Emtricitabine|DRUG: Efavirenz|DRUG: Darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the SIS Membrane on GBR and Early Loading of Maxillary Anterior Dental Implants
Status: COMPLETED
Conditions: Dental Implantation|Guided Bone Regeneration
Interventions: PROCEDURE: Early implant loading|PROCEDURE: Delayed implant loading|PROCEDURE: GBR using an SIS membrane|PROCEDURE: GBR using an Bio-Gide membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Bisphosphonates in the Treatment of Avascular Necrosis of the Femoral Head
Status: TERMINATED
Conditions: Femoral Head Avascular Necrosis
Interventions: DRUG: Pamidronate Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional Bevacizumab for Treating AIDS-associated Kaposi´s Sarcoma of the Larynx, Pharynx and Oral Cavity
Status: COMPLETED
Conditions: Kaposi´s Sarcoma
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult Subjects
Status: COMPLETED
Conditions: Drug Interaction|Healthy Volunteer
Interventions: DRUG: Entinostat|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Parathyroidectomy on Sleep
Status: COMPLETED
Conditions: Hyperparathyroidism
Interventions: PROCEDURE: Parathyroid Surgery|BEHAVIORAL: Telephone Interview|PROCEDURE: Parathyroid Surgery|BEHAVIORAL: Polysomnography (PSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortisone Treatment for the Prevention of Postoperative Pancreatitis and Pancreatitis-induced Complications After Pancreaticoduodenectomy and Distal Pancreatic Resection
Status: COMPLETED
Conditions: Postoperative Complications|Postoperative Pancreatitis
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Immunogenicity and Safety of TNFa Kinoid in Rheumatoid Arthritis With Secondary Resistance to TNFa Antagonists
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: TNFa Kinoid|BIOLOGICAL: TNF kinoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guayusa: The Effect of an Herbal Extract on Alertness and Mental Fatigue
Status: COMPLETED
Conditions: Attention Difficulties
Interventions: OTHER: Gel capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Repeated Doses of Foliglurax on Drug Metabolizing Enzymes in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Drug Cocktail|DRUG: Foliglurax|DRUG: midazolam iv
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citizen Science to Promote Sustained Physical Activity in Low-Income Communities
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: ALED Alone Physical Activity Program|BEHAVIORAL: ALED + Our Voice PA Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adolescents' Non-suicidal Behavior and Perception of Parents' Negative Emotional Expression and Family Communication
Status: NOT_YET_RECRUITING
Conditions: Adolescents
Interventions: OTHER: Questionnaires set 1|OTHER: Questionnaires set 2|OTHER: Questionnaires set 3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: P E P C A D II, The Paclitaxel-Eluting PTCA-Balloon Catheter in Coronary Artery Disease to Treat In-Stent Restenoses
Status: COMPLETED
Conditions: In-Stent Restenosis
Interventions: DEVICE: paclitaxel coated balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Temporal Interference Stimulation: Modulating Associative Memory by Targeting Deep-brain Targets
Status: NOT_YET_RECRUITING
Conditions: Healthy Aging|Memory Disorders in Old Age|Mild Cognitive Impairment|Alzheimer Disease
Interventions: COMBINATION_PRODUCT: Non-invasive Temporal Interference stimulation and Face-name association training task targeting the hippocampus|COMBINATION_PRODUCT: Non-invasive Temporal Interference stimulation and Face-name association training task targeting the Precuneus|COMBINATION_PRODUCT: High-frequency stimulation (placebo) with Face-name association training task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer
Status: COMPLETED
Conditions: Adnexal Mass|Borderline Ovarian Epithelial Tumor|Ovarian Clear Cell Tumor|Ovarian Endometrioid Tumor|Ovarian Neoplasm|Ovarian Serous Tumor|Recurrent Ovarian Carcinoma
Interventions: DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent Training for Parents of Toddlers Born Very Premature:
Status: RECRUITING
Conditions: Parenting|Problem Behavior|Premature Birth|Parenting Intervention
Interventions: BEHAVIORAL: ezParent|BEHAVIORAL: Coaching calls|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Operative Treatment of Intra-Articular Distal Radius Fractures With Versus Without Wrist Arthroscopy
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Additional wrist arthroscopy|PROCEDURE: ORIF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of CinnoVex (Interferon Beta-1a) Compared to Avonex (Interferon Beta-1a)
Status: COMPLETED
Conditions: Bioequivalence|Healthy
Interventions: DRUG: Interferon Beta-1A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent Placement
Status: WITHDRAWN
Conditions: Peripheral Pulmonary Stenosis|In-stent Stenosis
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimation of Coagulation Factor XIII Activity Based on the Initial Plasma Fibrinogen Level in Trauma
Status: COMPLETED
Conditions: Multiple Trauma|Coagulation Disorder|Coagulation Factor Deficiency|Coagulation Defect; Acquired
Interventions: DIAGNOSTIC_TEST: fibrinogen plasma concentration, coagulation factor XIII activity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality
Status: NOT_YET_RECRUITING
Conditions: All Cause Mortality|Cardiovascular Diseases|Invasive Cancer|Liver Cirrhosis|Type 2 Diabetes|Depression|Dementia|Injury Traumatic|Tuberculosis|Infections
Interventions: BEHAVIORAL: Moderate Alcohol Drinking Pattern|BEHAVIORAL: Abstention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Triclosan-coated Sutures in Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Wound Infection
Interventions: DEVICE: Triclosan coated sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VATS VS. Open Thoracic Surgery for Stage II - III Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Surgery
Interventions: PROCEDURE: VATS|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD
Status: COMPLETED
Conditions: Alcohol Dependence|Posttraumatic Stress Disorder (PTSD)
Interventions: DRUG: Topiramate|DRUG: placebo|BEHAVIORAL: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BrUOG 351: PRE-OPERATIVE APBI USING NIBB
Status: WITHDRAWN
Conditions: Breast Cancer|Invasive Breast Cancer|Ductal Carcinoma in Situ
Interventions: RADIATION: NIBB: accuboost|PROCEDURE: Partial mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Flipped Classroom Model on Teaching Clinical Practice Skills
Status: COMPLETED
Conditions: Flipped Classroom Model in Teaching
Interventions: BEHAVIORAL: The flipped classroom model was used to teach students' clinical practice skills.|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab Combined With SOX and/or Apatinib for Locally Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Locally Advanced Gastric Cancer
Interventions: DRUG: Camrelizumab combined with SOX/ or apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Glutamine Supplementation on Insulin Resistance and Functional Intestinal Disorders in Obese Patients.
Status: UNKNOWN
Conditions: Obesity|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Oral glutamine supplementation|DIETARY_SUPPLEMENT: Oral protein powder supplementation|PROCEDURE: Insulin-resistance evaluation|PROCEDURE: Functional intestinal disorders evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systolic Heart Failure
Status: TERMINATED
Conditions: Systolic Heart Failure
Interventions: DRUG: Placebo|DRUG: Udenafil (Zydena)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study and Transformation of Tumor Molecular Features Screening Model of Endometrial Carcinoma Surgical Approach
Status: NOT_YET_RECRUITING
Conditions: Endometrial Carcinoma|Tumor Molecular Features Screening Model
Interventions: PROCEDURE: open surgery|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Posttraumatic Elbow Stiffness Treatment
Status: COMPLETED
Conditions: Elbow Joint Contracture|Elbow Flexion Contractures|Elbow Injury|Elbow Osteoarthritis
Interventions: PROCEDURE: Elbow Open Arthrolyses|PROCEDURE: Non-surgical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Filgotinib in Adults With Active Noninfectious Uveitis
Status: TERMINATED
Conditions: Noninfectious Uveitis
Interventions: DRUG: Filgotinib|DRUG: Placebo to match filgotinib|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Pharmacokinetics Effects of Food on ASK120067 in Single Oral Administration in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Locally Advanced or Metastatic NSCLC
Interventions: DRUG: ASK120067|DIETARY_SUPPLEMENT: ASK120067 in fed condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESTIMATION OF GINGIVAL CREVICULAR LEVEL OF YKL40
Status: UNKNOWN
Conditions: Periodontitis and Rheumatoid Arthritis
Interventions: PROCEDURE: scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial With Chemotherapy, Immunotherapy, and Radiotherapy for Patients With Newly Diagnosed Stage IV Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Durvalumab|RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function.
Status: NOT_YET_RECRUITING
Conditions: Healthy|Older Adults|Overweight and Obesity
Interventions: OTHER: Nitrate-rich beetroot juice plus calorie-restricted diet|OTHER: Nitrate-rich beetroot juice plus weight-maintenance diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Allogenic Stem Cells Derived From Lipoaspirates for the Treatment of Recto-vaginal Fistulas Associated to Crohn's Disease (ALOREVA)
Status: COMPLETED
Conditions: Rectovaginal Fistula|Crohn Disease
Interventions: DRUG: Expanded allogenic adipose-derived adult stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE)
Status: NOT_YET_RECRUITING
Conditions: Right Ventricular Dysfunction
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: T1 Cardiovascular Magnetic Resonance|DIAGNOSTIC_TEST: Right heart catheterisation and coronary sinus blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Compare Combination of Aliskiren+ HCTZ to Irbesartan+ HCTZ or Amlodipine+ HCTZ or HCTZ Alone in Obese Hypertensive Not Responsive to HCTZ 25 mg
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: 111-Indium-CMD-193|DRUG: CMD-193
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Monitoring for Patients Post Coronary Interventions to Reduce Risk for Recurrent Adverse Cardiovascular Events
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: LiveCare|BEHAVIORAL: Text Messages|OTHER: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy
Status: UNKNOWN
Conditions: Stage III Esophageal Squamous Cell Carcinoma|Esophageal Neoplasms
Interventions: DRUG: Capecitabine(Aibin)|DRUG: Oxaliplatin(Aiheng)|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dalteparin Prophylaxis in High-Risk Ambulatory Cancer Patients
Status: TERMINATED
Conditions: Venous Thromboembolism|Pulmonary Embolism
Interventions: DRUG: dalteparin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nedaplatin (Jiebaishu®) Combined With Docetaxel for Advanced Lung Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Nedaplatin|DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Venetoclax in Japanese Participants With Relapsed and Refractory Chronic Lymphocytic Leukemia (Including Small Lymphocytic Leukemia)
Status: COMPLETED
Conditions: Cancer|Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Leukemia (SLL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults
Status: NOT_YET_RECRUITING
Conditions: Electronic Nicotine Delivery Systems|Tobacco Products|Cigarette Smoking
Interventions: BEHAVIORAL: EQUIP|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Residual Neuromuscular Blockade and of Late Recurarization in the Post Anesthesia Care Unit in Patients Undergoing Videolaparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Neuromuscular Block, Residual
Interventions: DRUG: Cisatracurium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Embolization in Surgical Treatment of Spinal Metastases.
Status: COMPLETED
Conditions: Spinal Metastases
Interventions: PROCEDURE: Arteriography and preoperative embolization|PROCEDURE: Arteriography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of In-bed Self-exercise in Patients With Subacute Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: in-bed self-exercises based on EMG-sensor feedback intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase I Clinical Study to Evaluate the Safety, the Tolerability, the Pharmacokinetic Characteristics and the Efficacy of ScTIL Injection (Genetically Modified Tumor Infiltrating Lymphocytes) in the Treatment of Advanced Malignant Solid Tumors
Status: UNKNOWN
Conditions: Advanced Tumor of Digestive Tract or Urinary System
Interventions: BIOLOGICAL: ScTIL injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of JNJ-42756493 Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42756493 Current Clinical Formulation (G-018)|DRUG: JNJ-42756493 Prototype Formulation I (G-025)|DRUG: JNJ-42756493 Prototype Formulation II (G-025)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome
Status: RECRUITING
Conditions: Cubital Tunnel Syndrome|Electrical Stimulation
Interventions: PROCEDURE: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Software for Assessment of Atrial Fibrillation From PPG Data Acquired by a Wearable Smartwatch
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Single lead ambulatory ECG patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing the Safety and Efficacy of Ziprasidone and Risperidone for the Treatment of Chronic Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Ziprasidone|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Play Based Therapy and Functional Communication Training in Speech-language Delayed Children
Status: RECRUITING
Conditions: Speech, Language Developmental Delay From Hearing Loss
Interventions: OTHER: Play Based Therapy|OTHER: Functional Communication Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Chronic Low Back Pain|Chronic Regional Pain Syndrome|Chronic Soft Tissue Pain
Interventions: DRUG: HZT-501
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Cytopenia With Multilineage Dysplasia|Refractory Cytopenia With Multilineage Dysplasia and Ringed Sideroblasts|Secondary Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Pretargeted Radioimmunotherapy|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil|RADIATION: Total-Body Irradiation|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Fludarabine Phosphate|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BKR-013 on Average Daily Glucose Levels
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: BKR-013 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Fat Levels and Abiraterone Acetate Uptake in Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: abiraterone acetate|DIETARY_SUPPLEMENT: dietary intervention|DIETARY_SUPPLEMENT: dietary intervention|OTHER: pharmacological study|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes
Status: RECRUITING
Conditions: Hiv|Tobacco Use
Interventions: BEHAVIORAL: EX+|DRUG: Varenicline|BEHAVIORAL: HR|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: 14C-labeled poziotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Preoperative Autologous Blood Donation and Tranexamic Acid in Revision Total Hip Arthroplasty
Status: COMPLETED
Conditions: Revision Total Hip Arthroplasty (RTHA)
Interventions: OTHER: transfused pre-operatively donated autologous blood.|DRUG: intravenous tranexamic acid (TXA) infusion|OTHER: transfused only allogeneic blood.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Oxaliplatin-Based Chemotherapy and Chemoradiotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Cancer|Gastroesophageal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Oxaliplatin|RADIATION: Radiation Therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine and Postoperative Pain Management
Status: UNKNOWN
Conditions: Postoperative Pain Management
Interventions: DRUG: Lidocaine|DRUG: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmenting Treatment Effects of Voice Therapy in Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Transcranial Magnetic Stimulation|BEHAVIORAL: Lee Silverman Voice Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Laparotomy Versus Percutaneous Puncture in Patients With Abdominal Compartment Syndrome During Acute Pancreatitis
Status: UNKNOWN
Conditions: Mortality|Acute Pancreatitis
Interventions: PROCEDURE: Decompressive laparotomy with temporary abdominal closure|PROCEDURE: Percutaneous puncture with placement of abdominal catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRC With Meniscal Allograft Arthroplasty for Wrist Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Wrist Osteoarthritis
Interventions: PROCEDURE: Meniscus Allograft Transplantation with Proximal Row Carpectomy|PROCEDURE: Proximal Row Carpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Non-powered AEON™ Endostapler and Echelon FLEX™ Powered Plus Stapler With Regards to the Closure of Lung Tissue After Lung Resection in the Presence of Severe Lung Emphysema
Status: RECRUITING
Conditions: Postoperative Air Leak|Lung Resection
Interventions: PROCEDURE: Non-powered AeonTM Endostapler (according to manufacturer medical device classification IIb)|PROCEDURE: Echelon FLEX™ Powered plus Stapler (according to manufacturer medical device classification IIb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis (UC) Participants Who Are Naive to Tumor Necrosis Factor (TNF) Inhibitors
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Etrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Exenatide|DRUG: Non-GLP-1 RA based glucose lowering drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ESCAP: Supervised Exercise for Patients With Coronary Heart Disease in the Primary Care Setting
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: BEHAVIORAL: Supervised exercise on a stationary bicycle, 3-5 days a week|BEHAVIORAL: Secondary prevention program for coronary heart disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome
Status: TERMINATED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III, Study to Evaluate the Efficacy of Two Different HBV Vaccination Schemes in Patients With Hepatic Cirrhosis
Status: COMPLETED
Conditions: Hepatitis B|Cirrhosis|Awaiting Organ Transplant
Interventions: BIOLOGICAL: HBV vaccine|BIOLOGICAL: HBV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Well-Being Therapy by Personalized Mobile Technology Program for Psychological Distress and Promote Healthy Behaviors
Status: COMPLETED
Conditions: Psychological Distress
Interventions: BEHAVIORAL: Well-Being Therapy based on Web Mobile Technology|BEHAVIORAL: Cognitive Behavior Therapy|OTHER: Standardized Care Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: S-648414|DRUG: Placebo|DRUG: Midazolam|DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Sleep in Idiopathic Hypersomnia
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Hypersomnia
Interventions: OTHER: EEG (64 electrodes)|OTHER: Cognitive task (SART)|OTHER: Pupillometry and eye tracking|OTHER: Thoracoabdominal belts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients With Weakened Immune Systems
Status: COMPLETED
Conditions: HIV Infections|Chickenpox
Interventions: DRUG: Netivudine|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Health Access and Recovery Peer Program
Status: COMPLETED
Conditions: Hypertension|Arthritis|Coronary Artery Disease|Hepatitis|Diabetes|Asthma|Hyperlipidemia|HIV
Interventions: BEHAVIORAL: HARP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Hematoma Block in Distal Radius Fractures
Status: RECRUITING
Conditions: Distal Radius Fractures|Fracture Dislocation|Dislocated Wrist|Dislocated Radius
Interventions: DEVICE: Ultrasound guided hematoma block.|PROCEDURE: Blind hematoma block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users
Status: COMPLETED
Conditions: Healthy Volunteers|Drug Users
Interventions: DRUG: EB-1020 400 mg|DRUG: EB-1020 800 mg|DRUG: lisdexamfetamine 150 mg|DRUG: d-amphetamine 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Betaine and Food on Gastric pH
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Standardized Meal|DIETARY_SUPPLEMENT: Betaine Hydrochloride 1500mg|DIETARY_SUPPLEMENT: Betaine Hydrochloride 3000mg|DIETARY_SUPPLEMENT: Betaine Hydrochloride 4500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Pharmacokinetics and Safety of Recombinant Human Murine Chimeric Anti CD20 Monoclonal Antibody Injection (IBI301) Compared to Rituximab Injection in CD20 Positive B Cell Lymphoma Patients
Status: COMPLETED
Conditions: B-Cell Lymphoma
Interventions: DRUG: IBI301|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency, Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults ≥ 50 Years of Age
Status: COMPLETED
Conditions: Herpes Zoster|Herpes Zoster Vaccine
Interventions: BIOLOGICAL: Herpes Zoster vaccine (GSK 1437173A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Red Cell Distribution Width Versus Presepsin (Soluble CD14) as a Prognostic Marker in Critically-ill Sepsis Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: Red Cell Distribution Width (RDW)|DIAGNOSTIC_TEST: Presepsin (sCD14-ST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Irreversible Electroporation (IRE) to Treat Early-Stage Primary Liver Cancer (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: Ablation with the NanoKnife Low Energy Direct Current (LEDC) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 10 Vs.15 mcg Norepinephrine Bolus in Severe Maternal Hypotension During Cesarean Delivery
Status: NOT_YET_RECRUITING
Conditions: Hypotension|Spinal Anesthesia|Cesarean Section
Interventions: DRUG: 10 mcg Norepinephrine|DRUG: 15 mcg Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended ECG Monitoring in HCM Patients
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy|Nonsustained Ventricular Tachycardia|Ventricular Tachycardia|Atrial Fibrillation|Arrhythmia
Interventions: DEVICE: Zio XT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Prostatectomy for Chronic Prostatitis
Status: UNKNOWN
Conditions: Prostatitis|Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: PROCEDURE: laparoscopic prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mechanism of Mindfulness Intervention to Alleviate Emotional Distress in Patients With Emotional Disorders
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress|Emotional Disorder
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis
Status: COMPLETED
Conditions: Carcinoma, Neuroendocrine
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MCI-196 in Chronic Kidney Disease Stage V Subjects on Dialysis With Hyperphosphatemia
Status: COMPLETED
Conditions: Chronic Kidney Disease|Dialysis|Hyperphosphatemia
Interventions: DRUG: MCI-196|DRUG: Another Phosphate binder (Sevelamer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grape Seeds Extract Gel as an Adjunct for the Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DIETARY_SUPPLEMENT: 2% GSE mucoadhesive gel|OTHER: GSE free mucoadhesive gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Dose Escalation Study of CAT-8015 in Patients With Non-Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: CAT-8015
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anaesthetic Efficacy of 2% Mepivacaine Versus 4% Articaine With Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Mepivacaine|DRUG: Articaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Lower Respiratory Disease
Interventions: OTHER: Cardio-Pulmonary Exercise Testing (CPET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-sex Female Controlled Human Schistosomiasis Mansoni Infection
Status: COMPLETED
Conditions: Schistosomiasis|Schistosomiasis Mansoni
Interventions: BIOLOGICAL: female Schistosoma mansoni cercariae
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Child and Family Traumatic Stress Intervention
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Child and Family Traumatic Stress Interv (CFTSI)|BEHAVIORAL: Psychoeducational Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zoledronic Acid in Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Zoledronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy
Status: COMPLETED
Conditions: Colorectal Cancer|Diarrhea|Neutropenia
Interventions: DRUG: fluorouracil|DRUG: leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Mindfulness-Based Treatment for Substance Use Disorder Recovery
Status: RECRUITING
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Treatment-as-Usual (TAU)|BEHAVIORAL: Digital Mindfulness Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Analyze the Impact of Treatment With Paliperidone Palmitate on Clinical Outcomes and Hospital Resource Utilization in Adult Participants With Schizophrenia in Portugal
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oral Antipsychotics (OAPs)|DRUG: Paliperidone Palmitate 1-Month Formulation (PP1M)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Severe Whitening and Delayed Fading in Acetic Acid-enhanced Endoscopy for Diagnosing Gastric Intestinal Metaplasia
Status: UNKNOWN
Conditions: Gastric Intestinal Metaplasia
Interventions: PROCEDURE: acetic acid-enhanced endoscopy|DRUG: Acetic Acid|DEVICE: endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Can Postprandial Reactive Hypoglycaemia be Reduced in Patients After Roux-en-Y Gastric Bypass With a Low Carbohydrate Diet?
Status: COMPLETED
Conditions: Bariatric Surgery (Gastric Bypass)
Interventions: OTHER: Low carbohydrate meals|OTHER: Standard carbohydrate meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inflammation in Chronic Kidney Disease and Cardiovascular Disease - The Role of Genetics and Interleukin-1 Receptor Antagonist (IL-1ra)
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiovascular Disease
Interventions: DRUG: Rilonacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Affects of Once-daily Oral Administration of TZP-102 on the Treatment of Symptoms Associated With Diabetic Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: 10mg TZP-102|DRUG: 20mg TZP-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Calcium and Multiple Micronutrient Supplements for Maternal and Newborn Hemoglobin and Iron Status
Status: NOT_YET_RECRUITING
Conditions: Anemia, Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Concurrent multiple micronutrient and calcium supplementation|DIETARY_SUPPLEMENT: Separate multiple micronutrient and calcium supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer
Status: TERMINATED
Conditions: Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment
Interventions: DRUG: CAM-H2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: BIOLOGICAL: Gamunex-C|BIOLOGICAL: IVIG-PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease
Status: COMPLETED
Conditions: Invasive Pneumococcal Infections|Sickle Cells Disease
Interventions: BIOLOGICAL: Vaccination with the combined vaccine (Prevenar13 ®)|BIOLOGICAL: Vaccination with the polysaccharide vaccine (Pneumo 23 ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE