pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Digoxin Antibodies Fab Fragments|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Adjuvant Chemotherapy With Bevacizumab and Maintenance Bevacizumab After Neoadjuvant Chemotherapy for Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients
Status: RECRUITING
Conditions: Intraocular Pressure|Oncology
Interventions: DRUG: TIVA|DRUG: Balanced anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rifaximin in Patients With Monoclonal Gammopathy
Status: RECRUITING
Conditions: IgA Monoclonal Gammopathy|IgG Monoclonal Gammopathy|IgM Monoclonal Gammopathy|Light Chain Deposition Disease|Monoclonal Gammopathy|Smoldering Waldenstrom Macroglobulinemia|Waldenstrom Macroglobulinemia|Gammopathy, Monoclonal|Gammopathy Igg
Interventions: DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Parent-child Sleep Intervention to Improve Sleep Quality, Psychological Health, and Infant Health in Parents of Neonates.
Status: NOT_YET_RECRUITING
Conditions: Sleep Quality|Psychological Health|Infant Health
Interventions: BEHAVIORAL: parent-child sleep intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Safety and Efficacy of CCX354-C in Subjects With Rheumatoid Arthritis Partially Responsive to Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CCX-354-C|DRUG: Placebo|DRUG: CCX354-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlative Analysis of the Genomics of Vitamin D and Omega-3 Fatty Acid Intake in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Turmeric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Capacitive-Resistive Therapy on the Treatment of Myofascial Pain
Status: COMPLETED
Conditions: Myofascial Pain Syndrome of Neck
Interventions: DEVICE: Capacitive-Resistive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microcirculatory Impairment in Patients With Leprosy
Status: COMPLETED
Conditions: Lepromatous Leprosy
Interventions: DRUG: acetylcholine Iontophoresis|DRUG: sodium nitroprusside Iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DRUG: Linaclotide or Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correction of Hallux Valgus With the Nexis® PECA Bunion Implantable Osteosynthesis Medical Device
Status: RECRUITING
Conditions: Hallux Valgus
Interventions: DEVICE: Nexis® PECA Bunion device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxytocin Effects on Self Versus Other Touch
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: oral lollipop with oxytocin (24IU)|DRUG: oral lollipop with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Efficacy of the Neoadjuvant Combination: "Chemotherapy-Targeted Therapy" in Breast Cancer.
Status: COMPLETED
Conditions: Pathological Response Rate
Interventions: DRUG: vectibix|DRUG: fluorouracile|DRUG: Epirubicine|DRUG: cyclophosphamide|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HRS-8080 Tablets in Metastatic or Local Advanced Breast Cancer of Adults
Status: ENROLLING_BY_INVITATION
Conditions: Metastatic or Local Advanced Breast Cancer of Patients
Interventions: DRUG: HRS-8080 tablets、SHR 6390 tablets、Abemaciclib、Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Estradiol, medroxyprogesterone, hydrocortisone, GH|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Multiple Immune and Disease Treatment Combinations in Participants With ER+HER2- Breast Cancer That Has Spread
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Adapalene/BPO Gel|OTHER: Moisturizer SPF 30|OTHER: Foam Wash
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Remifentanil and Flurbiprofen in Sedation and Analgesia for ESWL of Pancreatic Stone
Status: COMPLETED
Conditions: Pancreatic Stone Disease
Interventions: DRUG: Remifentanil|DRUG: Flurbiprofen and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injectable Collagen Scaffold™ Combined With HUC-MSCs Transplantation for Patients With Decompensated Cirrhosis
Status: UNKNOWN
Conditions: Decompensated Cirrhosis
Interventions: BIOLOGICAL: Conventional therapy|BIOLOGICAL: Injectable Collagen Scaffold + HUC-MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Leptin for the Treatment of Hypothalamic Amenorrhea
Status: COMPLETED
Conditions: Amenorrhea
Interventions: DRUG: r-metHuLeptin|DRUG: Oral Contraceptive Pills (OCPs)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Improving Staff Attitudes and Care for People With Dementia: eLearning
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Improving Wellbeing and Health for People with Dementia (WHELD) e-learning training programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of GEMS-H on Locomotor Function in Adults
Status: COMPLETED
Conditions: Adults|Middle Age|Aged|Aged, 80 and Over
Interventions: DEVICE: with Gait Enhancing and Motivating System-Hip (GEMS-H)|OTHER: without Gait Enhancing and Motivating System-Hip (GEMS-H)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
Status: NOT_YET_RECRUITING
Conditions: Thumb Osteoarthritis
Interventions: DRUG: Saline Hypertonic Solution|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery.
Status: COMPLETED
Conditions: Coronary Artery Disease|Pain Syndrome
Interventions: PROCEDURE: Ultrasound guided Bilateral Transversus Thoracis Muscle Plane block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deficit-specific Training in Spinal Disorders
Status: RECRUITING
Conditions: Spinal Cord Injuries|Multiple Sclerosis|Gait Disorders, Neurologic|Training|Neurorehabilitation
Interventions: BEHAVIORAL: Gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Telephone Symptom Triage Protocols in Patients With Cancer Therapy (TeleTRIAGE)
Status: COMPLETED
Conditions: Cancer|Self Efficacy
Interventions: BEHAVIORAL: The Effect of Telephone Symptom Triage Protocols on Symptom Management, Quality of Life and Self-Care Maintenance in Patients with Cancer Who Applied Systemic Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Oxaliplatin, Irinotecan, and Capecitabine in Advanced Gastric/Gastroesophageal Junction Carcinoma
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Gastric Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gastric Cancer|Stage IIIC Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: oxaliplatin|DRUG: irinotecan hydrochloride|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCS-05 in Patients With Acute Optic Neuritis
Status: RECRUITING
Conditions: Optic Neuritis|Optic; Neuritis, With Demyelination
Interventions: DRUG: OCS-05 IV administration|OTHER: Placebo IV administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Rehabilitation With Exoskeleton-assisted Gait.
Status: COMPLETED
Conditions: Severe Stroke|Acute Stroke|Chronic Stroke|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Vascular Diseases|Cardiovascular Diseases|Mild Stroke
Interventions: DEVICE: Exoskeleton-Assisted Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial on Video-assisted Thoracoscopic Surgery and Axillary Thoracotomy for Resection of Early-stage Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: video-assisted thoracoscopic surgery|PROCEDURE: axillary thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Candesartan and Telmisartan on Morning Hypertension in Japanese Obese Patients
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Candesartan|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2
Status: RECRUITING
Conditions: Breast Cancer|Lung Cancer|Genito-Urinary Cancer|Colorectal Cancer|Gastric Cancer|Pancreatic Cancer|Liver Cancer|Head and Neck Cancer|Melanoma
Interventions: BEHAVIORAL: Hello for Cancer game|OTHER: Table Topics game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Pharmacodynamics of BIWH 3 in Healthy Duffy Positive vs. Duffy Negative Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIWH 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Status: TERMINATED
Conditions: Gastric Cancer|Gastric Adenocarcinoma|Peritoneal Carcinomatosis|Peritoneal Metastases
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Low Versus Normal Pressure Pneumoperitoneum - With Profound Low Versus Normal Pressure Pneumoperitoneum -With Profound Muscle Relaxation- During Laparoscopic Donor Nephrectomy
Status: COMPLETED
Conditions: Renal Disease
Interventions: PROCEDURE: Low pressure pneumoperitoneum|PROCEDURE: Normal pressure pneumoperitoneum (12 mmHg)|PROCEDURE: Deep neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Port Site Pain Following Percutaneous Externally-Assembled Laparoscopic Donor Nephrectomy
Status: TERMINATED
Conditions: Laparoscopic Donor Nephrectomy
Interventions: DEVICE: Percuvance™ Percutaneous Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Robot-Assisted Gait Training in Patients With Spinal Cord Injury Caused by Electrical Burns: A Case Report
Status: NOT_YET_RECRUITING
Conditions: Gait Disorder, Sensorimotor|Burns|Spinal Cord Injuries
Interventions: PROCEDURE: robot assisted gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GRASPA (Erythrocytes Encapsulating L-asparaginase) in Patients With Relapse of Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, in Relapse
Interventions: DRUG: GRASPA|DRUG: L-asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baclofen in Managing Acute Alcohol Withdrawal
Status: UNKNOWN
Conditions: Alcohol Use Disorder|Alcohol Withdrawal
Interventions: DRUG: Diazepam 10 MG|DRUG: Baclofen 30mg|DRUG: Baclofen 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Longevity of Microwave Thermolysis and Botulinum Toxin A for Treatment of Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis Primary Focal Axilla
Interventions: DEVICE: Microwave thermolysis|DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bingo Drug-eluting Balloon in Bifurcation
Status: COMPLETED
Conditions: Bifurcation Lesions|Drug Eluting Balloon
Interventions: DEVICE: Drug-eluting balloon|DEVICE: Uncoated ballloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H-IVIG Treatment for Severe H1N1 2009
Status: COMPLETED
Conditions: Novel 2009 Influenza A (H1N1) Infection
Interventions: DRUG: Hyperimmune intravenous immunoglobulin|DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Acceptance Based Therapy for Adolescents Living With HIV
Status: COMPLETED
Conditions: Medication Adherence|Adjustment Reaction With Anxiety and Depression|Mental Health Issue
Interventions: BEHAVIORAL: Mindfulness and acceptance based therapy|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Raltegravir on Pravastatin Pharmacokinetics(GRAPPA)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Pravastatin|DRUG: Raltegravir|DRUG: Pravastatin and raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms Underlying the Sleep Promoting Effect of Cherry Juice Standardized to Its Proanthocyanidin Content
Status: COMPLETED
Conditions: Insomnia|Sleep Problem
Interventions: OTHER: 8-ounce glass of cherry juice|OTHER: Artificial Cherry Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of (61)CuATSM-PET Imaging in Cancer Patients
Status: TERMINATED
Conditions: CNS Brain Metastases|Head and Neck Cancer|Lung Cancer|Prostate Cancer|Esophageal Cancer
Interventions: PROCEDURE: PET-imaging with CuATSM|PROCEDURE: PET Imaging|PROCEDURE: PET CuATSM|PROCEDURE: PET imaging|PROCEDURE: PET imaging with CuATSM|PROCEDURE: PET imaging with CuATSM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction
Status: TERMINATED
Conditions: Diabetes Mellitus|Heart Failure
Interventions: DRUG: Tc99m-Maraciclatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Acetylsalicylic Acid and Low Molecular Weight Heparins on the Incidence of Renal Hematoma of Shockwave Lithotripsy
Status: COMPLETED
Conditions: Urolithiasis|Renal Hematoma
Interventions: DRUG: Acetylsalicylic acid|DRUG: low molecular weight heparin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Incentive Spirometry on Dyspnea and Chest Clearance in Asthmatic Patients During Seasonal Smog
Status: COMPLETED
Conditions: Shortness of Breath
Interventions: OTHER: INCENTIVE SPIROMETRY|OTHER: Active cycle of breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Preoperative Aspirin on Graft Patency and Cardiac Events in Off-pump Coronary Artery Bypass
Status: UNKNOWN
Conditions: Coronary Artery Disease|Off-pump Coronary Artery Bypass|Aspirin
Interventions: DRUG: aspirin|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Stage I Soft Tissue Sarcoma of the Trunk and Extremities|Stage II Soft Tissue Sarcoma of the Trunk and Extremities|Stage III Soft Tissue Sarcoma of the Trunk and Extremities
Interventions: PROCEDURE: Computed Tomography|OTHER: Educational Intervention|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration|OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Resistant Arterial Hypertension Cohort Study
Status: COMPLETED
Conditions: Hypertension|Essential Hypertension|Resistant Hypertension
Interventions: DRUG: chlorthalidone|BEHAVIORAL: motivational intervention for non-compliant individuals|DRUG: standardized anti-hypertensive treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Medulloblastoma
Interventions: RADIATION: Craniospinal Irradiation with boost to the primary tumor site|DRUG: Cyclophosphamide|DRUG: Cisplatin|DRUG: Vincristine|DRUG: Vismodegib|DRUG: Pemetrexed|DRUG: Gemcitabine|OTHER: Aerobic Training|OTHER: Neurocognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELITE: Early Versus Late Intervention Trial With Estradiol
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: 17B-estradiol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Administration of a Natural Molecular Complex in Functional Chronic Constipation
Status: RECRUITING
Conditions: Chronic Constipation
Interventions: DEVICE: Sollievo Fisiolax|OTHER: Sollievo Fisiolax Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: METHOXYFLURANE or Virtual Reality Headset vs Standard Analgesic Management for the Reduction of Anterior Shoulder Dislocation (HYPNOLUX)
Status: RECRUITING
Conditions: Anterior Shoulder Dislocation
Interventions: DEVICE: Helmet virtual reality.|DRUG: Administration of METHOXYFLURANE|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Certolizumab Pegol in Japanese Subjects With Moderate to Severe Chronic Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Psoriasis|Generalized Pustular Psoriasis and Erythrodermic Psoriasis
Interventions: OTHER: Placebo|DRUG: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Montelukast Sodium Chewable Tablets 4mg and 5mg Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Montelukast sodium chewable tablets 4mg and 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Postoperative Cognitive Function in Patients Undergoing Shoulder Arthroscopy With Beach Chair Position Under Desflurane Anesthesia
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care
Status: COMPLETED
Conditions: Colo-rectal Cancer
Interventions: OTHER: virtual technology - highly tailored|OTHER: virtual technology - tailored minimally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Pharmacokinetics of JNJ-56021927 in Participants With Mild or Moderate Hepatic Impairment Compared With Participants With Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: JNJ-56021927
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Antiviral Therapy and Immune Reconstitution of Chinese HIV/AIDS Patients
Status: UNKNOWN
Conditions: Acquired Immune Deficiency Syndrome|HIV Infections
Interventions: DRUG: first line ARV (3TC+NVP+D4T or 3TC+NVP+AZT)|DRUG: second line ARV therapy (3TC+TDF+LPV/RTV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tislelizumab Combined With DisitamabVedotin and Pyrotinib Maleate in HER2-positive or Mutated Advanced Colorectal Cancer Who Failed Standard Therapy
Status: NOT_YET_RECRUITING
Conditions: HER2-positive or Mutated Advanced Colorectal Cancer
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer|Endometrioid Tumor|Cancer|Tumor|Recurrent Endometrial Carcinoma|Endometrioid Endometrial Cancer
Interventions: DRUG: nab-sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Recurrent B Acute Lymphoblastic Leukemia|Recurrent Ph-Like Acute Lymphoblastic Leukemia|Refractory B Acute Lymphoblastic Leukemia|Refractory Ph-Like Acute Lymphoblastic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Doxorubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Ruxolitinib Phosphate|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of High Voltage Pulsed Current On Post-Traumatic Injuries
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DEVICE: Standard physical therapy and HVPC with positive polarity|DEVICE: high voltage pulse stimulation with negative polarity|OTHER: standard physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing Two Implant Surface Finishes in Patients Undergoing Cementless Total Hip Replacement
Status: TERMINATED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis|Avascular Necrosis|Acute Fracture
Interventions: DEVICE: non-coated femoral hip stem|DEVICE: coated femoral hip stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbial Growth in Operative Splash Basins During Total Joint Arthroplasty
Status: TERMINATED
Conditions: Periprosthetic Joint Infection
Interventions: OTHER: Sterile Water|OTHER: 3.5% Betadine|OTHER: 0.05% Chlorhexidine Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma
Status: RECRUITING
Conditions: Mucosal Melanoma of the Head and Neck
Interventions: DRUG: Pembrolizumab|RADIATION: Hypofractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bevacizumab in Combination With First-Line Chemotherapy in Patients Aged 75 Years of Older With Metastatic Colorectal Adenocarcinoma (Prodige20)
Status: COMPLETED
Conditions: Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: LV5FU2 simplified, FOLFOX 4 simplified, FOLFIRI modified|DRUG: LV5FU2 simplified,FOLFOX 4 simplified, FOLFIRI modified, Bevacizumab 5 mg/kg/ 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trifecta™ Long Term Follow-Up (LTFU) Study
Status: COMPLETED
Conditions: Aortic Valve Insufficiency|Aortic Valve Regurgitation|Aortic Valve Stenosis|Aortic Valve Incompetence
Interventions: DEVICE: Trifecta™ Valve
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Relative BioavailabilityStudy Of Ibuprofen 40mg/ml (laboratórios Pfizer Ltda) In The Oral Suspension Form.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alivium®|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults
Status: COMPLETED
Conditions: Lymphoma, Lymphoblastic
Interventions: DRUG: Dexamethasone/Prednisolone|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Asparaginase|DRUG: G-CSF|DRUG: Mercaptopurine|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: VP16|DRUG: Vindesine|DRUG: Adriamycin|DRUG: Thioguanine|DRUG: HDARAC|PROCEDURE: CNS irradiation|PROCEDURE: Mediastinal irradiation|DRUG: Cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.
Status: COMPLETED
Conditions: Virus Diseases|Rabies
Interventions: BIOLOGICAL: Rabipur|PROCEDURE: Blood sampling|BIOLOGICAL: Purified Chick-Embryo Cell Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: DRUG: Biodentine|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of High-Intensity Interval Nordic Walking in Patients With Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: High-intensity interval Nordic walking|BEHAVIORAL: Standard cardiovascular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Triamcinolone Paste to Reduce the Incidence of Postoperative Sore Throat
Status: COMPLETED
Conditions: Tracheal Intubation
Interventions: DRUG: triamcinolone acetonide|DRUG: chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg
Status: COMPLETED
Conditions: Lung Injury, Acute|Ventilator-Induced Lung Injury|Ventilator Adverse Event
Interventions: DEVICE: Mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EmergeNcy Department Apneic Oxygenation Versus Usual Care During Rapid Sequence Intubation
Status: COMPLETED
Conditions: Diffuse Apneic Oxygenation
Interventions: OTHER: Oxygen|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Mentalization-based Treatment And A Dialectical Behavior Therapy-inspired Treatment On The Utilization Of Services And The Dropout Rate In A Clinical Adult Population With A Cluster B Personality Disorder
Status: COMPLETED
Conditions: Cluster B Personality Disorder (Diagnosis)|Borderline Personality Disorder
Interventions: BEHAVIORAL: Mentalization-based Treatment|BEHAVIORAL: Dialectical Behavior Therapy-inspired Treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulating Early-life Nutrition for Childhood Obesity Prevention
Status: RECRUITING
Conditions: Infant Growth|Childhood Overweight
Interventions: DIETARY_SUPPLEMENT: Betaine supplementation in infant formula|DIETARY_SUPPLEMENT: Regular infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations
Status: ACTIVE_NOT_RECRUITING
Conditions: FGFR1 Gene Amplification|FGFR1 Gene Mutation|FGFR1 Gene Translocation|FGFR2 Gene Amplification|FGFR2 Gene Mutation|FGFR2 Gene Translocation|FGFR3 Gene Amplification|FGFR3 Gene Mutation|FGFR3 Gene Translocation|Metastatic Colorectal Carcinoma|Stage III Colorectal Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Unresectable Colorectal Carcinoma
Interventions: DRUG: Pemigatinib|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MEDI-522 Administered by Subcutaneous Injection to Adults With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: MEDI-522|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule Under Fed Condition
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Mycophenolate Mofetil Capsule 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Children, Adolescents and Adults in Russia
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Radial Artery Deviation And Reimplantation Technique for Primary Hemodialysis Access Creation
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: PROCEDURE: End-cephalic vein to side-radial artery fistula creation|PROCEDURE: RADAR fistula creation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tailored Antiplatelet Therapy Following PCI
Status: COMPLETED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome|Stenosis
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Synbiotics on FC and Other Contributing Factors
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Tolerance of Afatinib in Combination With Docetaxel and Cisplatin in LAHNSCC Induction Chemotherapy
Status: COMPLETED
Conditions: HNSCC
Interventions: DRUG: Taxotere, Cisplatin, Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Blocks for Ileostomy Takedown: A Prospective Study
Status: TERMINATED
Conditions: Ileostomy - Stoma
Interventions: PROCEDURE: Transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell
Interventions: DRUG: Atezolizumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Intermittent Theta Burst Stimulation for Depressive Symptoms
Status: COMPLETED
Conditions: Depression and Suicide
Interventions: DEVICE: Dorsolateral Prefrontal Cortex Accelerated Theta Burst Stimulation|DEVICE: Anterior Cingulate Cortex Accelerated Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Avenanthramide-Enriched Oats in Healthy Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Avenanthramide-enriched oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer(NSCLC)
Interventions: DRUG: AT13387|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Efficacy and Safety of Ariva® Silver Wintergreen in Healthy Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking
Interventions: OTHER: Ariva Silver Wintergreen|OTHER: Ariva Wintergreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients With Advanced Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Vismodegib 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Vasomotion of People With Idiopathic Chilblains
Status: COMPLETED
Conditions: Chilblains|Perniosis|Thermoregulation
Interventions: BEHAVIORAL: Assessment of Vasomotion of People With Idiopathic Chilblains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of an Augmented Mobilization Strategy With Plerixafor (Mozobil®) in a Population at Risk for Poor Stem Cell Mobilization
Status: COMPLETED
Conditions: Multiple Myeloma|Lymphoma
Interventions: DRUG: Plerixafor|OTHER: Observation: Nonintervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Tape (TVT) Secur Versus TVT Randomised Controlled Trial (RCT)
Status: TERMINATED
Conditions: Urinary Incontinence, Stress
Interventions: PROCEDURE: TVT Secur (Gynecare)|PROCEDURE: TVT (Gynecare)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC (Cabatezo-1)
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|NSCLC Stage IV|Metastatic NSCLC - Non-Small Cell Lung Cancer|Advanced NSCLC
Interventions: DRUG: Cabozantinib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin for the Treatment of Postprandial Hypoglycemia
Status: TERMINATED
Conditions: Postprandial Hypoglycemia
Interventions: DRUG: Empagliflozin (Jardiance®;|OTHER: Placebo Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcome Following Concomitant Surgical Ablation for Atrial Fibrillation at University Hospital Basel: A Retrospective Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Maze Procedure
Interventions: PROCEDURE: Surgical Ablation for Atrial Fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Metformin, prolonged-release tablets 500 mg (JSC Farmak, Ukraine)|DRUG: Glucophage® XR 500 mg prolonged release tablets (Merck Serono Ltd, UK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Growth Hormone Releasing Hormone in HIV
Status: COMPLETED
Conditions: HIV|HIV Lipodystrophy
Interventions: DRUG: tesamorelin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: SK-PC-B70M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Specimen PET-CT Imaging for Intraoperative Margin Assessment in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Cancer Invasive|Breast Cancer in Situ
Interventions: DIAGNOSTIC_TEST: high-resolution PET-CT specimen imaging.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trauma-Focused Intervention With Women Experiencing Homelessness
Status: RECRUITING
Conditions: Psychological Trauma|Trauma and Stress Related Disorders|Substance-Related Disorders|Substance Use|Substance Use Disorders
Interventions: BEHAVIORAL: Immediate Narrative Exposure Therapy (NET)+|BEHAVIORAL: Waitlist + NET+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S9918 PSC 833, Daunorubicin, and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: valspodar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer
Status: TERMINATED
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer AJCC V7|Stage IIA Prostate Cancer AJCC v7
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Informational Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Diabetic Foot
Interventions: BIOLOGICAL: 3 x 10^6 cells|BIOLOGICAL: 10 x 10^6 cells|BIOLOGICAL: 30 x 10^6 cells|BIOLOGICAL: 100 x 10^6 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition to Relieve IBS Constipation
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Constipation
Interventions: DIETARY_SUPPLEMENT: Probiotic supplement|DIETARY_SUPPLEMENT: Prebiotic supplement|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Oral Navelbine in Female Patients With HER2-Negative Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
Interventions: DRUG: Oral NVB Metronomic|DRUG: Oral NVB Weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT