pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Role of Dutasteride in Patients Undergoing 3D Mapping Biopsy in Early Stage Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Dutasteride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acquiring and Targeting Heat Exposures Necessary for Action
Status: RECRUITING
Conditions: Heat Intolerance|Heat Stress|Fatigue; Heat
Interventions: DIETARY_SUPPLEMENT: Antioxidant Berry Supplementation|OTHER: Acute and Chronic Exercise-Heat Stress|DIETARY_SUPPLEMENT: Placebo (non-juice) Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibrosis.
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: ARCT-032|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Approach in Adults Followed up in Spanish Hospitals for Heart Failure (BOCADOS-IC)
Status: RECRUITING
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: MULTIDOMAIN NUTRITIONAL INTERVENTION: DIET, EXERCISE AND NUTRITIONAL SUPPLEMENTS|DIETARY_SUPPLEMENT: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coracoid Tunnel Widening After ACJ Tight Rope Fixation
Status: COMPLETED
Conditions: Orthopedic Disorder|Orthopedic Devices Associated With Misadventures
Interventions: PROCEDURE: arthroscopic fixation of Acute acromioclavicular joint injury using tight rope|DEVICE: Tight rope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Breathing Exercises and Meditation on Reducing Stress and Improving Quality of Life of Glaucoma Patients: An Electronic Pilot Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Stress|Quality of Life
Interventions: BEHAVIORAL: Breathing Exercises followed by Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vasoactive and Anti-inflammatory Effects of Prasugrel in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Unstable Angina
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR
Status: RECRUITING
Conditions: Kinematical Alignment,Mechanical Alignment, Navigation
Interventions: PROCEDURE: alignment types
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Cutaneous Lupus
Interventions: DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastectomy
Status: UNKNOWN
Conditions: Pain, Acute|Erector Spinae Plane Block|Mastectomy, Modified Radical|Thoracic Interfascial Plane Block|Pain, Chronic
Interventions: PROCEDURE: Ultrasound guided Thoracic Interfascial plane Block (TIFB)|PROCEDURE: Ultrasound guided Erector Spinae plane Block (ESPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate the in Silico Optimization of Insulin Treatments
Status: UNKNOWN
Conditions: Coronary Artery Bypass
Interventions: OTHER: Standard Glucommander Protocol (SGP)|OTHER: Optimized Glucommander (OGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multicomponent Intervention for Physical Frailty and Sarcopenia
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: OTHER: Multicomponent intervention (MCI)|OTHER: Healthy Aging Lifestyle Education (HALE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Immune Response in Adults and Elderly Subjects Vaccinated With Inactivated Influenza Vaccines
Status: COMPLETED
Conditions: Influenza|Orthomyxovirus Infections|Myxovirus Infection
Interventions: BIOLOGICAL: Inactivated, split-virion, influenza vaccine|BIOLOGICAL: Inactivated, split-virion, influenza vaccine|BIOLOGICAL: Inactivated, split-virion influenza vaccine|BIOLOGICAL: Inactivated, split-virion influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy
Status: RECRUITING
Conditions: IgA Nephropathy|Immunoglobulin A Nephropathy
Interventions: DRUG: Atrasentan|DRUG: Atrasentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine in the Treatment of Osteoarthritis (OA) in the Elderly
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Buprenorphine|DRUG: Codeine paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Tecogalan sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Beta-agonist Efficacy and Tolerability as Adjuvant Therapy in Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: DRUG: Salbutamol 4Mg Tablet|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Moderate-Dose Steroid Therapy in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of a Novel Laser-aided Orthodontic-periodontal Treatment Strategy
Status: UNKNOWN
Conditions: Periodontal Disease
Interventions: DEVICE: low-level laser therapy|OTHER: orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Allergic Diseases
Status: COMPLETED
Conditions: Atopic Dermatitis|Asthma
Interventions: BIOLOGICAL: LP GMNL-133 capsule|BIOLOGICAL: LF GM-090 capsule|BIOLOGICAL: LP GMNL-133 +LF GM-090 capsule|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Nerve-sparing Radical Hysterectomy on Patients' Urinary Dynamics
Status: COMPLETED
Conditions: Cervical Cancer|Urinary Retention
Interventions: PROCEDURE: BiClamp group|PROCEDURE: water jet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic Study of Lidocaine Patch 1.8% (ZTlido™) and Lidocaine Patch 5% (Lidoderm®) in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lidocaine topical system 1.8%|DRUG: Lidocaine patch 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Allopurinol Combination Study
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: RDEA594|DRUG: Placebo|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Structural Effect and Long-term Symptomatic Relief of Intra-articular Injections of Hyaluronic Acid in Primary Knee OA
Status: UNKNOWN
Conditions: Osteoarthritis Of Knee
Interventions: DEVICE: Intra-Articular Hyaluronic Acid|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iberdomide and Daratumumab as Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Daratumumab/rHuPH20 Co-formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Carcinoma|Gastric Adenocarcinoma|GEJ Adenocarcinoma|Esophageal Adenocarcinoma|Cholangiocarcinoma|Gallbladder Carcinoma
Interventions: DRUG: tucatinib|DRUG: trastuzumab|DRUG: oxaliplatin|DRUG: leucovorin|DRUG: fluorouracil|DRUG: capecitabine|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Oral Probiotic Bacteria Supplementation to Reduce Chronic Immune Activation in HIV-infected Malian Women
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: VSL#3® probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Chemotherapy of Nanoparticle Albumin-bound Paclitaxel in Squamous Cell Carcinoma of Esophagus
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma of Esophagus
Interventions: DRUG: nanoparticle albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Preliminary Efficacy of LY-M001 Injection in the Treatment of Adult Patients With Gaucher Disease Type I
Status: RECRUITING
Conditions: Gaucher Disease Type I
Interventions: BIOLOGICAL: LY-M001 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function
Status: RECRUITING
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: NNC0194-0499
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Femoral Prothesis-rotation in Conventional X-ray, in Axial CT Slices and 3D-reconstructed CT
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Kanekasu radiographs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Radiotracer [18F]Fluortriopride ([18F]FTP) by PET/CT
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: [18F]Fluortriopride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IMRT Combined With Toripalimab in Unresectable Locally Recurrent Nasopharyngeal Carcinoma.
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Nasopharyngeal Diseases|Head and Neck Neoplasm
Interventions: DRUG: Tolipalimab|RADIATION: Reirradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Specialized Assertive Intervention for First Episode Psychosis
Status: COMPLETED
Conditions: First Episode Psychosis of Schizophrenia and Schizotypal Disorder|Psychotic Disorders|Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: 2 years OPUS treatment|BEHAVIORAL: OPUS 5 years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Shingles|Herpes Zoster|Vaccine-Preventable Diseases
Interventions: BIOLOGICAL: Z-1018|BIOLOGICAL: Z-1018|BIOLOGICAL: Z-1018|BIOLOGICAL: Z-1018|BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Plasma Concentration of Somatostatin and Endocannabinoids After GA and RA in Upper Extremity Trauma Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Arm Injury
Interventions: PROCEDURE: Upper extremity surgery under general anaesthesia|PROCEDURE: Upper extremity surgery under regional anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of Mefloquine and Dihydroartemisinin-Piperaquine in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mefloquine and Dihydroartemisinin-piperaquine|OTHER: Wash-out period|DRUG: Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Dementia, Vascular|Lewy Body Disease|Frontotemporal Lobar Degeneration|Memory Disorders
Interventions: BEHAVIORAL: Navigated Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Probiotic on Oral Health of Children
Status: UNKNOWN
Conditions: Oral Disease
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo - No probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identification and Characterization of Molecular Markers in Musculoskeletal Tumors
Status: TERMINATED
Conditions: Soft Tissue and Bone Tumors|Sarcoma|Sarcoma of Bone|Soft Tissue Sarcoma
Interventions: OTHER: Identification and characterization of molecular markers in musculoskeletal tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dietary Polyphenols and Glycation in Renal Insufficiency
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency, Chronic
Interventions: DIETARY_SUPPLEMENT: Chlorogenic Acid (CGA) enriched coffee|DIETARY_SUPPLEMENT: Conventional coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion
Status: COMPLETED
Conditions: Bone Resorption
Interventions: DRUG: Platelet Rich Plasma|DRUG: No Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREDICTIVE IMMUNOLOGICAL STUDY OF RECURRENT ABORTIONS AND IMPLANTATION FAILURE
Status: COMPLETED
Conditions: Maternal-Fetal KIR-HLA-C Compatibility
Interventions: DIAGNOSTIC_TEST: HLA-C and KIR determination for patients, couples, oocyte or semen donors, abortive tissue and newborn.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Gather Information About Rivaroxaban in Patients in Sweden With Cancer Who Also Have Thrombosis (OSCAR-SE)
Status: COMPLETED
Conditions: Treatment of Venous Thromboembolism in Cancer Patients
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Low molecular weight heparin (LMWH)|DRUG: vitamin K antagonist (VKA)|DRUG: other NOACs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer
Status: RECRUITING
Conditions: Oligometastatic Breast Carcinoma|Breast Cancer|Metastatic Breast Cancer|Metastatic Breast Carcinoma|ER+ Breast Cancer|HER2+ Breast Cancer
Interventions: RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases
Status: COMPLETED
Conditions: Central Nervous System Lymphoma|Malignant Glioma|Metastatic Malignant Neoplasm in the Brain
Interventions: PROCEDURE: 3 Tesla Magnetic Resonance Imaging|PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|PROCEDURE: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging|DRUG: Ferumoxytol|DRUG: Gadolinium|PROCEDURE: MRI-Based Angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diverting Loop Ileostomy: With or Without Rod
Status: TERMINATED
Conditions: Ileostomy|Rectal Neoplasms
Interventions: PROCEDURE: Diverting loop ileostomy with rod|PROCEDURE: diverting loop ileostomy without rod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study Of A Self Complementary Adeno-Associated Viral Vector For Gene Transfer in Hemophilia B
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia B
Interventions: GENETIC: Gene Transfer|DRUG: scAAV2/8-LP1-hFIXco
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Agreement Between Oral and Cervical Human Papillomavirus Infection in a French Cohort
Status: COMPLETED
Conditions: Human Papillomavirus-Related Cervical Carcinoma
Interventions: OTHER: Agreement between oral and cervical HPV infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Grading Versus Classic Inferior Oblique Anterior Transposition in Patient With Asymmetric Dissociated Vertical Deviation
Status: UNKNOWN
Conditions: Asymmetric Dissociated Vertical Deviation
Interventions: PROCEDURE: Grading Inferior Oblique Anterior Transposition surgery|PROCEDURE: Classic Inferior Oblique Anterior Transposition surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RDD Versus VDD in Newly Diagnosed Patients With Multiple Myeloma
Status: UNKNOWN
Conditions: Hematologic Neoplasms|Multiple Myeloma|Efficacy|Safety
Interventions: DRUG: RDD|DRUG: VDD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SeroCOVIDial Study: Assessment of COVID-19 Seroconversion in Patients on Chronic Hemodialysis and in Their Caregivers, a Cohort Study
Status: UNKNOWN
Conditions: Chronic Hemodialysis Patients|Caregivers of Chronic Hemodialysis Patients
Interventions: BIOLOGICAL: Blood sample|BIOLOGICAL: Serum tube collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)
Status: TERMINATED
Conditions: Carotid Artery Disease|Carotid Stenosis|Stroke|Atherosclerosis
Interventions: DEVICE: Carotid artery stenting with filter (interventional)|PROCEDURE: Carotid artery endarterectomy (surgical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease Who Completed Protocol CL0600-008
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Teduglutide (ALX-0600)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Bronchodilation of Symbicort With and Without Valved Holding Chamber (Aerochamber Plus)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: pMDI budesonide/formotrol 160/4.5 is in group 1|DEVICE: Symbicort 160/4.5 plus Aerochamber Plus included in group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anterior Versus Posterior Laparoscopic Mesh Rectopexy For Rectal Prolapse; a Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Rectal Prolapse
Interventions: PROCEDURE: Laparoscopic anterior mesh rectopexy|PROCEDURE: Laparoscopic posterior mesh rectopexy|DEVICE: polypropylene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III (LONG-DES-III)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Cypher|DEVICE: Xience V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Cognitive Intervention for Youth Post Concussion
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Concussion, Mild
Interventions: OTHER: Cognitive Orientation to Occupational Performance (CO-OP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: OTHER: Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plyometric Exercise-induced Mechano-morphological Changes of Plantar Flexor Muscle-tendon Unit in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Plyometric Exercises|OTHER: Standard Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylselenocysteine Effects on Circadian Rhythm
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Methylselenocysteine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Endoloop Pre-test to Treat Gastroesophageal Reflux
Status: UNKNOWN
Conditions: GERD|Reflux Esophagitis
Interventions: DEVICE: Endoscopic endoloop pre-test treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Servo-Ventilation In-lab PSG Evaluation
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: Philips BiPAP AutoSV Advanced System One|DEVICE: Modified Philips BiPAP ASV|DEVICE: ResMed S7 VPAP Adapt|DEVICE: ResMed S9 VPAP Adapt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
Status: RECRUITING
Conditions: Prurigo
Interventions: DRUG: Ruxolitinib Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PuraPly™ Antimicrobial Wound Matrix and Wound Management
Status: COMPLETED
Conditions: Pressure Ulcer|Venous Ulcer|Diabetic Ulcer|Surgical Wound|Trauma Wound
Interventions: DEVICE: PuraPly™ Antimicrobial Wound Matrix
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Investigation of Erlotinib as an HCV Entry Inhibitor
Status: UNKNOWN
Conditions: Chronic Hepatitis C Infection|HCV Genotype 1b
Interventions: DRUG: 1- Erlotinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Regional Anesthesia Techniques After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Acute|Knee Arthropathy|Postoperative Pain|Mobility Limitation
Interventions: PROCEDURE: continuous anesthesia of adductor canal|PROCEDURE: continuous anesthesia of femoral nerve|PROCEDURE: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tocotrienols Supplementation on Platelet Aggregation in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Platelet Aggregation, Spontaneous
Interventions: DIETARY_SUPPLEMENT: Tocotrienol-rich fraction 400mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: BIOLOGICAL: BNT162b5 Bivalent (WT/OMI BA.2)|BIOLOGICAL: BNT162b2 Bivalent (WT/OMI BA.1)|BIOLOGICAL: BNT162b2 Bivalent (WT/OMI BA.4/BA.5)|BIOLOGICAL: BNT162b5 Bivalent (Original/OMI BA.4/BA.5)|BIOLOGICAL: BNT162b6 Bivalent (Original/OMI BA.4/BA.5)|BIOLOGICAL: BNT162b7 Bivalent (Original/OMI BA.4/BA.5)|BIOLOGICAL: BNT162b7 Monovalent (OMI BA.4/BA.5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DEVICE: Intermittent Theta-burst stimulation (iTBS)|DEVICE: Continuous Theta-burst stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interaction of Cocoa Methylxanthines With Cocoa Flavanol Related Vascular Effects
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: flavanol|DIETARY_SUPPLEMENT: methylxanthine|DIETARY_SUPPLEMENT: flavanol + methylxanthine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Quitline Support Study
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: 1-Call Quitline Counseling|BEHAVIORAL: 4-Call Quitline Counseling|DRUG: Nicotine patch|DRUG: Nicotine Patch and Nicotine Lozenge|BEHAVIORAL: SmokefreeTXT|BEHAVIORAL: No SmokefreeTXT|BEHAVIORAL: Financial Incentives for Treatment Engagement|BEHAVIORAL: No Financial Incentives for Treatment Engagement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quatitative MRI of the Spinal Cord in Cervical Myelopathy: Assessment of Microstuctural Damage for Outcome Improvement
Status: RECRUITING
Conditions: Cervical Myelopathy
Interventions: DIAGNOSTIC_TEST: MRI standard and qMRI|OTHER: MEPs and SSEPs|OTHER: Neuromotor assessment|PROCEDURE: Anterior cervical discectomy and fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis
Interventions: BEHAVIORAL: Cognitive rehabilitation|BEHAVIORAL: Standard Psychological care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Curcumin C3 Complex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential Tremor
Status: ENROLLING_BY_INVITATION
Conditions: Essential Tremor
Interventions: DIAGNOSTIC_TEST: Clinical examination, blood draw, cerebral MRI, sonography, tremor analysis, OCT, olfactory mucosa swab.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Head and Neck Carcinoma|Trauma
Interventions: OTHER: Non-ICU Specialty ward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer
Status: TERMINATED
Conditions: Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Verrucous Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Verrucous Carcinoma of the Larynx|Tongue Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|RADIATION: external beam radiation therapy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels
Status: RECRUITING
Conditions: Drug Monitoring|Carcinoma, Non-Small-Cell Lung|Lung Cancer|Anaplastic Lymphoma Kinase Gene Mutation|Anaplastic Lymphoma Kinase Gene Translocation
Interventions: DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Usual Brand Cigarette|OTHER: Electronic Cigarette #1|OTHER: Electronic Cigarette #2|OTHER: Leading U.S. Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Irreversible Pulpitis|Postoperative Pain
Interventions: DRUG: Diclofenac Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Effects of Ticagrelor Versus Clopidogrel
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor + ASA + Bivalirudin|DRUG: Clopidogrel + ASA + Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTA 402 in Patients With Advanced Solid Tumors or Lymphoid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoid Malignancies
Interventions: DRUG: Bardoxolone methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACUNA (Traditions and Connections for Urban Native Americans)
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use|Alcohol Drinking|Marijuana Use
Interventions: BEHAVIORAL: TACUNA plus Wellness Circle|BEHAVIORAL: Opioid Education Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Therapy for First Line Treatment of Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Advanced Cervical Cancer
Interventions: DRUG: Anlotinib, Toripalimab, Paclitaxel, Cisplatin/ Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an HIV-1 Subtype C Vaccine (AVX101) in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: AVX101|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)
Status: COMPLETED
Conditions: Primary Myelofibrosis|Post-Polycythemia Vera Myelofibrosis|Post-Essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Momelotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback In Treatment Resistant Depression
Status: TERMINATED
Conditions: Depression|Neurofeedback
Interventions: DEVICE: neurofeedback augmentation|DRUG: treatment as usual|OTHER: psychotherapy placebo sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin
Status: COMPLETED
Conditions: Nosocomial Neonatal Sepsis
Interventions: DRUG: Cefazolin|DRUG: Vancomycin|DRUG: Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research on Cognitive Effect of Cannabidiol on Dravet Syndrome and Lennox-Gastaut SyndromeGastaut Syndrome
Status: UNKNOWN
Conditions: Dravet Syndrome|Lennox Gastaut Syndrome
Interventions: DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Subcutaneous Progestogen Implants in the Medical Management of Painful Endometriosis
Status: TERMINATED
Conditions: Endometriosis
Interventions: DEVICE: Nexplanon®|DRUG: Minidril®/Leeloo®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Response of Intracardiac Thrombus to Anticoagulants in Patients With Non-valvular Atrial Fibrillation (LYSIS)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Intracardiac Thrombus
Interventions: OTHER: Observational; No Interventions were given.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anticholinergic vs. Botox Comparison Study
Status: COMPLETED
Conditions: Urge Urinary Incontinence|Overactive Bladder
Interventions: DRUG: Botulinum toxin A (Botox A®)|DRUG: Solifenacin 5mg|DRUG: Solifenacin 10mg|DRUG: Trospium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: STP705
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of GABA Supplementation in the Progression of Type 1 Diabetes in Children
Status: WITHDRAWN
Conditions: Diabetes Mellitus
Interventions: DRUG: gamma-amino-butyric acid|DIETARY_SUPPLEMENT: Xylitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Attention Deficit Hyperactivity Disorder in Kindergarten and Pre-Kindergarten Children
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Friendship Group|BEHAVIORAL: Academic tutoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Kahook Dual Blade Ab-interno Trabeculotomy Versus ab Externo Viscotrabeculotomy in Primary Congenital Glaucoma
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Congenital Glaucoma
Interventions: PROCEDURE: ab externo viscotrabeculotomy|PROCEDURE: The Kahook dual blade® (KDB) assisted ab-interno trabeculotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Values of Voiding Diary for Diagnosis and Treatment for Monosymptomatic Enuresis in Children
Status: UNKNOWN
Conditions: Nocturnal Enuresis
Interventions: DIAGNOSTIC_TEST: the 3-day voiding diary|DIAGNOSTIC_TEST: the 7-day voiding diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patients
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Antiplatelet Drugs in Diabetic pAtients
Status: WITHDRAWN
Conditions: Diabetes
Interventions: DRUG: Clopidogrel, Prasugrel, Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy Adults
Status: COMPLETED
Conditions: QT Intervals Changes|QTc Intervals Changes
Interventions: DRUG: Omecamtiv Mecarbil (OM)|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine Periodic Therapy for Dysfunctional Uterine Bleeding During Adolescence With Yin Deficiency and Blood Heat Syndrome
Status: COMPLETED
Conditions: Dysfunctional Uterine Bleeding
Interventions: DRUG: Kidney-tonifying and tune up Chong-Ren hemostasis Chinese medicine|DRUG: Gong Xue Ning capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erectus Nerve Block for Lumbar Spine Surgery
Status: COMPLETED
Conditions: Spine Surgery|Pain Relief|Morphine|AdverseEvent
Interventions: DRUG: Local administration of ropivacaine|DRUG: Local administration of placebo (saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NASVAC Phase-III Trial in Chronic Hepatitis B (CHB) Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: NASVAC|DRUG: Pegylated interferon alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wallis Interspinous Dynamic Stability System for Lumbar Disc Herniation: a Prospective Study
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: Lumbar discectomy|PROCEDURE: Lumbar discectomy combined with Wallis interspinous dynamic stability system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Denervation of Pulmonary Arteries in Treatment of IPAH & SPAH
Status: UNKNOWN
Conditions: Hypertension, Pulmonary
Interventions: DEVICE: nMARQ Circular and Crescent catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Two Doses of aH5N1 Vaccine in Adult and Elderly Subjects With and Without Underlying Medical Conditions
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Novartis Investigational H5N1 vaccine|BIOLOGICAL: Novartis Investigational H5N1 vaccine|BIOLOGICAL: Novartis Seasonal Influenza Vaccine|BIOLOGICAL: Novartis Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Mobile Phone Text-based Intervention to Reduce Sedentary Behavior and Engage Communities on the Importance of Healthy Lifestyles: the TEXT2MOVE Study
Status: RECRUITING
Conditions: Life Style|Healthy Lifestyle
Interventions: DEVICE: FitBit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study to Access the Pharmacokinetics of HMS5552 in Hepatic Impaired Subjects and Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HMS5552
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of CML Patients With Imatinib and Hydroxyurea (CML2004)
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions: DRUG: Imatinib|DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Single-dose, Two-arm Parallel Study to Compare the Pharmacokinetics and Safety of BAT1806 Prefilled Subcutaneous Injection With RoActemra® in Healthy Chinese Male Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Men
Interventions: DRUG: BAT1806 prefilled subcutaneous injection/RoActemra® (from EU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY3372993 in Participants With Alzheimer's Disease (AD) and Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Healthy
Interventions: DRUG: LY3372993|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Economic Analysis of Early vs Delayed Therapy in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma:
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: OTHER: EQ-5D-5L Instrument|OTHER: Work Productivity and Daily Activity Impairment (WPAI) survey|OTHER: Resource Utilization Form (SMRC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Centre Study in Healthy Volunteers to Optimise the Rotacap Formulation and ROTAHALER Device for Delivery of Fluticasone Propionate/Salmeterol
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SERETIDE Rotacaps|DRUG: SERETIDE Diskus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT