pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Iron Sucrose in Patients With Iron Deficiency and POTS
Status: WITHDRAWN
Conditions: Iron-deficiency|Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: Sucrose|DRUG: Placebo|DIAGNOSTIC_TEST: Tilt Table Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: LUM/IVA|DRUG: LUM/IVA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empowering Patients With Chronic Disease Using Profiling and Targeted Feedbacks Delivered Through Wearable Device
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Nudges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Multicomponent Treatment for Fibromyalgia (FIBROWALK)
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: TAU + multicomponent treatment FIBROWALK|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of Intensity-Modulated Radiotherapy(IMRT)in Patients With Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: RADIATION: INTENSITY MODULATED RADIOTHERAPY|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial
Status: COMPLETED
Conditions: Postoperative Depression
Interventions: DRUG: Ketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Evaluation of Ten Allergy Skin Prick Test Devices
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma|Food Allergy|Skin Testing
Interventions: DEVICE: Histamine skin testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: capsules containing: carbidopa (25 mg), levodopa (100 mg), entacapone (200 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gestational Diabetes After Gastric Bypass Surgery
Status: RECRUITING
Conditions: Diabetes, Gestational|Gastric Bypass Status for Obesity Complicating Pregnancy, Childbirth, or the Puerperium|Pregnancy in Diabetic|Blood Glucose Self Monitoring
Interventions: DEVICE: FreeStyle Libre 2, continous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chromogranin A as Blood Marker in Cancer Patients
Status: COMPLETED
Conditions: Gastric Neoplasms|Pancreatic Neoplasms|Small Intestinal Neoplasms|Colorectal Neoplasms
Interventions: DIAGNOSTIC_TEST: BRAHMS CgA II KRYPTOR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DBS for TRD With the Medtronic Summit RC+S
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DEVICE: Medtronic Summit RC+S DBS system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Acetylcysteine for Contrast-Induced Nephropathy Trial
Status: COMPLETED
Conditions: Acute Kidney Failure
Interventions: DRUG: Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Video-Assisted Operating Room Introduce Program (VIASP-OR)
Status: UNKNOWN
Conditions: Anxiety|Parent-Child Relations
Interventions: DEVICE: Video-Assisted Operating Room Introduce Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain|Hysterectomy
Interventions: DRUG: Saline|DRUG: Butorphanol tartrate|DRUG: Tramadol Hydrochloride|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients
Status: RECRUITING
Conditions: Organ Failure, Multiple|Indigestion|Delayed Gastric Emptying|Respiratory Failure|Morality
Interventions: OTHER: traditional Chinese medicine|OTHER: Routine ICU care|OTHER: historical Routine ICU care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Exercise in Falls Prevention
Status: COMPLETED
Conditions: Falls Prevention|Prevention of Fall-related Injuries
Interventions: DIETARY_SUPPLEMENT: exercise and vitamin D supplementation|DIETARY_SUPPLEMENT: exercise and vitamin D supplementation|DIETARY_SUPPLEMENT: exercise and vitamin D supplementation|DIETARY_SUPPLEMENT: exercise and vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue
Status: UNKNOWN
Conditions: Sjogren's Syndrome
Interventions: DRUG: dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: rHGH and Intestinal Permeability in Intestinal Failure
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Somatropin|PROCEDURE: Seven Day Food Diary|PROCEDURE: Blood Tests (standard of care)|OTHER: Fasting|OTHER: Sugar Permeability Test|OTHER: Urine Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments
Status: TERMINATED
Conditions: Dental Caries|Dental Atraumatic Restorative Treatment|Oral Health
Interventions: OTHER: Subjective vs objective criteria in selective excavation|OTHER: Glass-ionomer vs Bulk fill composites in the ART approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Gut Microbiota and Metabolites for Very Preterm Infants Through Oropharyngeal Administration of Colostrum
Status: UNKNOWN
Conditions: Gut Microbiota|Metabolites
Interventions: OTHER: Oropharyngeal administration of colostrum|OTHER: Oropharyngeal administration of sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia
Status: COMPLETED
Conditions: Dyskinesia|Levodopa-Induced Dyskinesia (LID)|Parkinson's Disease (PD)
Interventions: DRUG: ADS-5102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cocoa Flavanol and Coronary Vasomotion Vascular Function in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Stable Coronary Heart Disease
Interventions: DIETARY_SUPPLEMENT: flavanol-rich drink vs flavanol-free drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection
Status: COMPLETED
Conditions: Malaria, Falciparum|Malaria, Vivax
Interventions: DRUG: OZ439
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia
Status: COMPLETED
Conditions: Ischemia|Peripheral Arterial Disease|Peripheral Vascular Diseases
Interventions: DEVICE: Micronized Small Intestinal Submucosa (SIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Registry to Study the Tined Lead Used With the InterStim System For Urinary Control
Status: TERMINATED
Conditions: Urge Incontinence|Urinary Retention
Interventions: DEVICE: Device Medtronic InterStim Tined Leads Models 3889 and 3093
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older Population
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GERAS Frailty Rehabilitation at Home During COVID-19
Status: COMPLETED
Conditions: Frailty
Interventions: BEHAVIORAL: Socialization|BEHAVIORAL: Virtual Group Exercise|COMBINATION_PRODUCT: Nutrition Consult and Protein Supplementation|BEHAVIORAL: Medication Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Breathing and Muscle Relaxation Technique in Individual With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: OTHER: Slow Breathing Exercise (SBE)|OTHER: Progressive Muscle Relaxation (PMR) Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: European Paediatric AFM Associated With EV-D68 Follow-up Study.
Status: UNKNOWN
Conditions: Flaccid Hemiplegia|Flaccid Paraplegia|Flaccid Tetraplegia, Unspecified|Enterovirus D68|Myelitis, Infectious
Interventions: DIAGNOSTIC_TEST: HFMS, MRC, ACTIVLIM, PedsQl-4.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Eye Movement Desensitization and Reprocessing (EMDR) in Alcohol Dependent Patients
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: BEHAVIORAL: EMDR|BEHAVIORAL: Community Reinforcement Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding and Safety of 2 Intradermal MEN-ACYW135-conjugate Vaccines
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MEN-ACYW135 reduced-dose intradermal administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modulation of Vascular Calcification in Chronic Dialysis Patients
Status: COMPLETED
Conditions: Vascular Calcification
Interventions: DEVICE: Medium Cut-Off (MCO) dialysis membrane|DEVICE: High-Flux dialysis membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Placebo|DRUG: Vilazodone|DRUG: Vilazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of [¹⁴C]-LY3484356 in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [¹⁴C]-LY3484356|DRUG: LY3484356|DRUG: [¹⁴C]-LY3484356 (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Astaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory Indicators
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: astaxanthin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Trial of Intravenous Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Zoledronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Fluoxetine 60 mg|DRUG: Naltrexone 32 mg and fluoxetine 60 mg|DRUG: Naltrexone SR 32 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
Status: RECRUITING
Conditions: Recession, Gingival
Interventions: DEVICE: Use of collagen matrix after subepithelial connective tissue graft harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraureteral Lidocaine for Post-Ureteroscopy Pain
Status: UNKNOWN
Conditions: Ureteral Calculi|Renal Calculi
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Traumatic Femoral Fractures|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: SmartSet® HV bone cement|DEVICE: SmartSet® GHV bone cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy
Status: RECRUITING
Conditions: Cervical Spondylosis With Myelopathy|Degenerative Cervical Myelopathy
Interventions: DIAGNOSTIC_TEST: 3T MR Imaging of the cervical spinal cord|OTHER: Positron Emission Tomography using [11C]PIB|OTHER: 3T MR Imaging of the Brain|OTHER: 7T MR Imaging of the Spinal Cord
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Docetaxel and Epirubicin With and Without G-CSF in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Neutropenia
Interventions: BIOLOGICAL: filgrastim|DRUG: docetaxel|DRUG: epirubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients
Status: COMPLETED
Conditions: Immunologic Deficiency Syndrome|Agammaglobulinemia|Severe Combined Immunodeficiency|Wiskott-Aldrich Syndrome|Common Variable Immunodeficiency
Interventions: DRUG: Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified|DRUG: Dextrose, 5% in Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FG-4592 for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Anemia|Myelodysplastic Syndrome
Interventions: DRUG: FG-4592|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Effect of Ticagrelor Versus Prasugrel on the Adenosine-induced Coronary Vasodilatory Responses in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAMOVID : Evaluation of Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Camostat Mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mometasone vs Budesonide in CRS With Polyposis
Status: TERMINATED
Conditions: Chronic Rhinosinusitis (Diagnosis), Nasal Polyposis
Interventions: DRUG: Budesonide 0.5 MG/ML|DRUG: Mometasone nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efalizumab Combined With Intravitreal Ranibizumab in the Treatment of Age-Related Macular Degeneration
Status: WITHDRAWN
Conditions: Age Related Macular Degeneration|AMD|CNV
Interventions: DRUG: Efalizumab, Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cam Type FAI is a Cause of Hip Pain in the Young Adult and a Precursor to OA
Status: RECRUITING
Conditions: Hip Dysplasia|Femoroacetabular Impingement|Osteoarthritis
Interventions: RADIATION: Low-dose CT Scan|OTHER: Blood/Urine Collection|OTHER: Patient Reported Questionnaires|RADIATION: EOS Scan|RADIATION: PET-MRI|OTHER: Motion Analysis|RADIATION: 3T MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Scintigraphic Detection of the Biodistribution of Tumor Necrosis Factor With a Radiolabeled Anti-TNFα in Patients With Active Rheumatoid Arthritis and Active Axial and Peripheral Spondyloarthritis
Status: COMPLETED
Conditions: Axial and Peripheral Spondyloarthritis|Rheumatoid Arthritis
Interventions: DRUG: administration of Cimzia®|DRUG: Immunoscintigraphy with radiolabeled Cimzia®.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction
Status: UNKNOWN
Conditions: Amphetamine Addiction|Pharmacotherapy
Interventions: DRUG: Dextromethorphan|DRUG: Memantine|DRUG: Dextromethorphan and memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PH Sensitive MRI Based Resections of Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: PROCEDURE: CEST PH MRI based resection of glioblastoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Media Based Peer-Led Intervention for HIV Prevention
Status: COMPLETED
Conditions: HIV Prevention|PrEP Uptake
Interventions: BEHAVIORAL: E-PrEP- Peer-Led Intervention about PrEP|BEHAVIORAL: BxNow - General Health Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Participants With Asthma (0476-911)
Status: COMPLETED
Conditions: Exercise Induced Asthma
Interventions: DRUG: Montelukast sodium|DRUG: Salmeterol xinafoate|DRUG: Fluticasone propionate|DRUG: Montelukast matching placebo|DRUG: Salmeterol matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of the E-health Education on Shared Care Program for Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: E-health Education|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Intranasal Corticosteroids on Systemic Allergen Specific IgE
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pelvic IMRT With Tomotherapy: A Phase I Feasibility Study in Post-Hysterectomy Cervical Cancer Patients
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: RADIATION: IMRT with tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Possible Immuno-Modulatory Effect of Tocilizumab in Patients With Refractory Status Epilepticus.
Status: UNKNOWN
Conditions: Epilepsy
Interventions: DRUG: Tocilizumab Prefilled Syringe [Actemra]. propofole, phenobarbital, midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Single Doses of MK2637 and Dextromethorphan on Cerebral Cortex Excitability (2637-008)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK2637|DRUG: Comparator: MK2637|DRUG: Comparator: Placebo|DRUG: Comparator: Dextromethorphan|DRUG: Comparator: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Zambian Informed Motivated Aware Responsible Adolescent Girls and Adults
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: ZAIMARA|BEHAVIORAL: Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study
Status: COMPLETED
Conditions: Diabetes Insipidus|Polydipsia, Primary
Interventions: DIAGNOSTIC_TEST: Arginine infusion|DIAGNOSTIC_TEST: Hypertonic saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Rizatriptan in the Treatment of Acute Attacks of Post-traumatic Headache in U.S. Military Troops
Status: WITHDRAWN
Conditions: Chronic Post-traumatic Headache
Interventions: DRUG: Rizatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Range Finding Study for MK0893 (0893-008)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: MK0893|DRUG: Metformin|DRUG: Placebo to MK0893|DRUG: Placebo to Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)
Status: COMPLETED
Conditions: Geographic Atrophy|Macular Degeneration
Interventions: DRUG: Avacincaptad Pegol|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: enasidenib|DRUG: Arm 1 probes|DRUG: Arm 2 Probes|DRUG: Arm 3 probes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Control and Surgical Site Infection Incidence Among Liver Transplantation Recipients
Status: TERMINATED
Conditions: Liver Transplantation|Surgical Wound Infection
Interventions: PROCEDURE: Strict Glycemic Control Group|PROCEDURE: Standard Glycemic Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLN4924 for the Treatment of Acute Myelogenous Leukemia, Myelodysplastic Syndrome, and Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: MLN4924|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability, and Effectiveness of an Individualized Plant-based (iPLANT) Diet Plan in Colorectal Cancer: Mixed Method Embedded Design
Status: RECRUITING
Conditions: Colorectal Cancer|Nutrition Poor|Gastrointestinal Complication|Quality of Life
Interventions: BEHAVIORAL: iPLANT diet plan and diet counselling|BEHAVIORAL: Usual diet counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Educational Strategy IN Exchange Transfusion
Status: UNKNOWN
Conditions: Newborn Morbidity|Simulation Training|Telemedicine|Assessment, Self
Interventions: OTHER: Digital didactic environment|OTHER: • Simulated scenario
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial of Internet-Based Cognitive Behavioral Therapy for Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Internet cognitive behavioral therapy for insomnia (iCBTI)|BEHAVIORAL: Class in sleeping well and improving insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Foot Muscle Fatigue on the Foot Sole and Tendon Structural Properties
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DEVICE: Evaluation of Viscoelastic and mechanical properties with MyotonPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Application of 18F-PSMA PET / CT Imaging in Prostate Specific Membrane Antigen Positive Tumor
Status: RECRUITING
Conditions: Malignancy
Interventions: DRUG: Al18F-PSMA-BCH PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of Dietary Protein and Blood Pressure
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension|Heart Diseases
Interventions: DIETARY_SUPPLEMENT: Soy protein-milk protein-carbohydrate|DIETARY_SUPPLEMENT: Milk protein-carbohydrate-soy protein|BEHAVIORAL: Carbohydrate-soy protein-milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Goal Setting Intervention on Exercise in Women With Metastatic Breast Cancer: An Exploration of The Lipogenic Pathway
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: BEHAVIORAL: Physical Activity Goal Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Drilling Techniques on Primary Stability and Marginal Bone Loss of Extra Short Implants
Status: NOT_YET_RECRUITING
Conditions: Different Surgical Techniques in Dental Implant Surgery
Interventions: PROCEDURE: Conventional dental implant surgery|PROCEDURE: Low Speed Drilling Without Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Cryotherapy or Cortisone Aerosol Therapy in Early Post-operative Swallowing Disorders Following Total Thyroidectomy
Status: COMPLETED
Conditions: Thyroidectomy|Post-operative Swallowing Disorders
Interventions: PROCEDURE: thyroidectomy|OTHER: cryotherapy|DRUG: cortisone aerosol|DRUG: Dexamethasone acetate|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Trial of Gemcitabine, Carboplatin, and Bevacizumab in Chemotherapy Naive Patients With Advanced/Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Myeloproliferative Disorder|Urothelial Carcinoma|Cancer
Interventions: DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of INRECSURE and LISA in Preterm Neonates With RDS
Status: RECRUITING
Conditions: Respiratory Distress Syndrome|Bronchopulmonary Dysplasia
Interventions: DEVICE: Ventilator for High-frequency Oscillatory Ventilation (HFOV)|DEVICE: Less invasive surfactant administration (LISA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction
Status: ACTIVE_NOT_RECRUITING
Conditions: Allergic Rhinoconjunctivitis|Grass Pollen Allergy
Interventions: BIOLOGICAL: Dupixent®|BIOLOGICAL: Grazax®|DRUG: Dupixent® Placebo|DRUG: Grazax® Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glivec® Plus m-FOLFOX Avastin® in Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Imatinib, Fluorouracil, Oxaliplatin, Leucovorin and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MinMed: Do Older Adults do Better With Less Medication
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Adverse Drug Interaction|Frailty
Interventions: OTHER: Medication minimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Impact of Mindful Interoceptive Mapping and Mindful Breathing on Pain and Opioid Use
Status: COMPLETED
Conditions: Pain, Chronic|Opioid Use
Interventions: BEHAVIORAL: Mindfulness of Breath|BEHAVIORAL: Mindful Interoceptive Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mechanistic Insights From Temporary Pacing in HFpEF
Status: NOT_YET_RECRUITING
Conditions: Heart Failure Preserved Ejection Fraction|Pacing
Interventions: DIAGNOSTIC_TEST: Acute Haemodynamic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Celecoxib for Pediatric Adenotonsillectomy
Status: COMPLETED
Conditions: Tonsillectomy|Adenotonsillectomy|Pain, Postoperative
Interventions: DRUG: Celebrex suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Status: COMPLETED
Conditions: AIDS-Related Non-Hodgkin Lymphoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Hepatocellular Carcinoma|HIV Infection|Kaposi Sarcoma|Locally Advanced Lung Non-Small Cell Carcinoma|Locally Advanced Malignant Solid Neoplasm|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Non-Hodgkin Lymphoma|Recurrent Classic Hodgkin Lymphoma|Recurrent Malignant Neoplasm|Refractory Classic Hodgkin Lymphoma|Refractory Malignant Neoplasm|Stage III Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Unresectable Melanoma
Interventions: DRUG: Antiretroviral Therapy|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Airway Removal During Deep Anesthesia in Children
Status: UNKNOWN
Conditions: Post Operative Sore Throat After LMA Removal
Interventions: OTHER: LMA removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV
Status: ACTIVE_NOT_RECRUITING
Conditions: AIDS-Related Human Papillomavirus Infection|High Grade Cervical Squamous Intraepithelial Neoplasia|HIV Infection
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients
Status: COMPLETED
Conditions: Shock
Interventions: DEVICE: ImaCor PM|DEVICE: ImaCor SM|OTHER: Control PM|OTHER: Control SM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Almonertinib/Pemetrexed/Carboplatin in EGFR T790M+ Advanced Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer, Non-small Cell|EGFR T790M|EGFR Gene Mutation
Interventions: DRUG: Almonertinib|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Investigating Safety and Performance of a New Urinary Intermittent Catheter in Healthy Volunteers
Status: COMPLETED
Conditions: Incontinence, Urinary
Interventions: DEVICE: Coloplast Test Catheter|DEVICE: Coloplast Speedicath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Characterisation of Healthy Volunteers, Asthma and Chronic Obstructive Pulmonary Disease Patients for Inhalation Profile, Pharyngometry, Spirometric Indices and Lung Morphometry
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Inhalation Profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aerosolized Vancomycin in Methicillin-Resistant Staphylococcus Aureus Pneumonia Under Mechanical Ventilation
Status: COMPLETED
Conditions: Pneumonia, Staphylococcal|Methicillin-Resistant Staphylococcus Aureus
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery
Status: RECRUITING
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Endonasal endoscopic pituitary surgery in semi-sitting position|PROCEDURE: Endonasal endoscopic pituitary surgery in supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Versus Four Implant-supported Fixed Full-arch Prosthesis
Status: COMPLETED
Conditions: Prosthesis Durability
Interventions: PROCEDURE: placement of four dental implants|PROCEDURE: placement of two dental implants|DEVICE: mandibular full arch prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety & Reactogenicity of GSK Bio's Human Rotavirus (HRV) Vaccine in Filipino Infants at Least 6 Weeks of Age at First Vaccination
Status: COMPLETED
Conditions: Infections, Rotavirus|Rotavirus Vaccines
Interventions: BIOLOGICAL: Rotarix|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders
Status: COMPLETED
Conditions: Infertility|Premature Ovarian Failure
Interventions: DRUG: Ganirelix 0.25mg (Orgalutran, Organon, The Netherlands)|DRUG: Arvekap 0.1mg (Triptorelin, Ipsen, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Intervention for Loneliness
Status: COMPLETED
Conditions: Loneliness
Interventions: BEHAVIORAL: Interpretation Bias Modification for Loneliness|BEHAVIORAL: Healthy Habits Psychoeducation and Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Angiography: Multislice CT Versus Invasive Heart Catheterization (CACTI)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: PROCEDURE: MS-CT Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in Participants Resistant to Aromatase Inhibitor Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: GDC-0941|DRUG: GDC-0941 Matching Placebo|DRUG: GDC-0980|DRUG: GDC-0980 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: THE EFFECTS OF MIRABEGRON AND TAMSULOSIN FOR PATIENTS WITH URETERAL STENTS
Status: COMPLETED
Conditions: Ureteral Stone|Kidney Stones|Ureteral Stenosis
Interventions: DRUG: Mirabegron 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: BIOLOGICAL: Canakinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation in the Surgical Pathway Before Major Lung Surgery
Status: UNKNOWN
Conditions: Smoking Cessation|Thoracic Surgery
Interventions: BEHAVIORAL: Integrated Behavioural therapy|DRUG: Integrated Pharmacotherapy|DEVICE: Integrated Web-based application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopy
Status: COMPLETED
Conditions: Peptic Ulcer
Interventions: DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease
Status: COMPLETED
Conditions: Inherited Mitochondrial Disease, Including Leigh Syndrome
Interventions: DRUG: Cysteamine Bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial That Compare Two Treatments in Newly Diagnosed Myeloma Patients Not Eligible for Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|New Diagnosis Tumor
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting
Status: COMPLETED
Conditions: Severe Traumatic Pain|Numeric Pain Rating Scale > 5 / 10
Interventions: DRUG: Morphine|DRUG: Sufentanil|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Effects of Melatonin Trial in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Japanese Safety Study of VEGF Trap-Eye in DME (Diabetic Macular Edema)
Status: COMPLETED
Conditions: Macular Edema
Interventions: BIOLOGICAL: VEGF Trap-Eye (BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)
Status: TERMINATED
Conditions: Coronary Disease|Heart Valve Diseases
Interventions: DRUG: CTI-01 (ethyl pyruvate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
Status: ACTIVE_NOT_RECRUITING
Conditions: Femur Neck Fracture|Arthroplasty Complications
Interventions: PROCEDURE: Total hip replacement arthroplasty using modular dual mobility cup|PROCEDURE: Total hip replacement arthroplasty using conventional acetabular cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Vaccine Therapy, and Stem Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: GVAX|PROCEDURE: Autologous transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: placebo|DRUG: flurbiprofen|DRUG: acetaminophen 650mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-centre Study to Compare Efficacy and Safety of AFOLIA and Gonal-f in Women for Assisted Reproductive Treatment
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Follitropin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Injections of HRS9531 in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: HRS9531|DRUG: Placebo|DRUG: Dulaglutide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT