pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Liraglutide 3.0 on Body Fat Distribution
Status: COMPLETED
Conditions: Obesity, Visceral|Cardiovascular Diseases|Fat Disorder
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PARIS or PAtch RIng Study: A Trial to Evaluate NuvaRing Versus OrthoEvra
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: ethinyl estradiol/etonogestrel vaginal ring|DRUG: ethinyl estradiol/norelgestromin transdermal contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects to Determine the Effects When Alcohol is Administered With Perampanel
Status: COMPLETED
Conditions: Central Nervous System
Interventions: DRUG: alcohol + placebo|DRUG: alcohol + perampanel|DRUG: perampanel + alcohol|DRUG: placebo + alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria
Status: COMPLETED
Conditions: Vivax Malaria
Interventions: DRUG: Dihydroartemisinin/piperaquine + primaquine|DRUG: Artesunate-amodiaquine + primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of TL-925 For The Treatment of AC
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: TL-925|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation, Repeated and Single Oral Dosing Study
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: APD791|DRUG: Clopidogrel|DRUG: Aspirin|DRUG: Placebo for APD791
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases
Status: SUSPENDED
Conditions: COVID-19|Upper Respiratory Infection|Lower Respiratory Infection
Interventions: DEVICE: Fitbit|DEVICE: Douglas Bag|DEVICE: Periflux 6000 EPOS|DEVICE: BIOPAC|DEVICE: Flowmet|DEVICE: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effects of the STAR Maneuver on UGRA Training
Status: COMPLETED
Conditions: Simulator-based Training of Ultrasound-guided Regional Anesthesia
Interventions: BEHAVIORAL: STAR|BEHAVIORAL: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of a Cryogenic Medical Device for Treatment of Common and Plantar Warts
Status: COMPLETED
Conditions: Warts
Interventions: DEVICE: Cryogenic treatment of warts (Pixie CO2)|DEVICE: Cryogenic treatment of warts (Wortie®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of MCO HD on Markers of Vascular Health Compared With On-Line Haemodiafiltration
Status: COMPLETED
Conditions: End Stage Renal Disease|Cardiovascular Diseases|Inflammation
Interventions: DEVICE: Medium Cut-Off Haemodialysis|DEVICE: On-Line Haemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Driving Ability Evaluation System to Improve the Conditional Driving License System: Safety and Feasibility Study.
Status: RECRUITING
Conditions: Automobile Driving
Interventions: DEVICE: VR Driving Simulator|OTHER: Computerized Neurocognitive Function Test|OTHER: Driver Test Station|OTHER: On-road field driving Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Differences in Flare Reaction Incidence and Intensity Following Trigger Finger Injections
Status: COMPLETED
Conditions: Trigger Finger
Interventions: DRUG: Betamethasone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Transcutaneous Electrical Stimulation Medical Device's Safety and Effectiveness in Treating the Patients With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Elexir (trigeminal nerve electrical stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials for Single Oral Dose of 60mg Fimasartan and Single IV Infusion of 30mg Fimasartan to Evaluate the Absolute Bioavailability of Kanarb® Tablet (Fimasartan) in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fimasartan|DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Triple-blinded Non-inferiority Multicentre Randomized Controlled Trial Comparing Hybrid and Fully Etched Implants P1
Status: RECRUITING
Conditions: Dental Implants
Interventions: PROCEDURE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: OTHER: FFR via central venous line|OTHER: FFR via peripheral venous line
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Computer-aided Detection During Screening Colonoscopy
Status: RECRUITING
Conditions: Colorectal Polyp|Colorectal Cancer|Colorectal Adenoma
Interventions: DIAGNOSTIC_TEST: HD- colonoscopy|DIAGNOSTIC_TEST: HD-colonoscopy assisted by AI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Wolman/CESD Natural History Chart Review and Longitudinal Follow-Up
Status: COMPLETED
Conditions: Wolman Disease|Cholesterol Ester Storage Disease|Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Interventions: OTHER: There are no interventions in this study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervention to Reduce Serious Mental Illness and Suicide Stigma Among Medical Students
Status: UNKNOWN
Conditions: Stigmatization|Clinical Competence
Interventions: BEHAVIORAL: SMI/SIA Stigma Reduction Intervention|OTHER: Disaster Preparedness Course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: liraglutide|DRUG: glimepiride|DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myelogenous Leukemia
Interventions: DRUG: MGCD0103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Preterm Birth With Probiotics
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Befotertinib Adjuvant Therapy in Stage IA2-IB NSCLC Patients
Status: RECRUITING
Conditions: 3-year Disease-free Survival
Interventions: DRUG: Befotertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine, Oxaliplatin, and Paclitaxel in Patients With Refractory Germ Cell Carcinoma
Status: COMPLETED
Conditions: Testicular Cancer|Germ Cell Neoplasm
Interventions: DRUG: paclitaxel, gemcitabine, and oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Educational Intervention on the Knowledge, Depression and Self-efficacy of Patients With Cerebrovascular Accident
Status: COMPLETED
Conditions: Effectiveness of Application Education Intervention
Interventions: OTHER: Intervention:APP educational programs|OTHER: No Intervention:general care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Cardiac CT in Acute Chest Patients With Intermediate Level Initial High-sensitivity Cardiac Troponin
Status: UNKNOWN
Conditions: Chest Pain|Coronary Artery Disease|Acute Coronary Syndrome|Ischemic Heart Disease
Interventions: DIAGNOSTIC_TEST: Cardiac CT angiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Surveillance of Lung Development During Childhood, Adolescence and Adulthood in Healthy and Patients With Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Healthy
Interventions: DIAGNOSTIC_TEST: Lung function test|DIAGNOSTIC_TEST: Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Respiratory Aerosols in Patients With COVID-19 and Healthy Controls
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection|Covid19
Interventions: DIAGNOSTIC_TEST: Resp-Aer-Meter|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Qualitative and quantitative virus PCR of respiratory secretions in patients with high aerosol concentrations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Information-Motivation-Behavioral Skills Model on Disease Management of Adolescents With Epilepsy
Status: COMPLETED
Conditions: Nursing Caries
Interventions: BEHAVIORAL: Information-Motivation-Behavioral Skills Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of AUY922 With Trastuzumab in HER2+ Advanced Breast Cancer Patients Previously Treated With Trastuzumab
Status: COMPLETED
Conditions: Advanced HER2-positive Breast Cancer
Interventions: DRUG: AUY922|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Three Toothpastes Using an in Situ Caries Model
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: 0.425 % w/w phytate,1150ppm F|DRUG: 0.85 % w/w phytate,1150ppm F|DRUG: 0.85 % w/w phytate,0.3%ZnCl2 0.5% sodium citrate, 1150ppm F|OTHER: 0 ppm F|DRUG: 1150ppm F|DRUG: 0.3%ZnCl2, 0.5% sodium citrate, 1150ppm F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Maternal Obesity and/or the By-pass on the Growth and the Nutritional Balance of the Child
Status: UNKNOWN
Conditions: Maternal Obesity
Interventions: OTHER: Collection of bloods samples for the mother|OTHER: Retrieval of umbilical cord blood.|OTHER: Retrieval of placenta.|OTHER: Collection of newborn's and mother's lock of hair.|OTHER: Dietetic Patient Outcomes Questionnaires for the mother.|OTHER: Parental questionnaires : ASQ (Ages & Stages questionnaires) and CFQ (Child Feeding Questionnaire).
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter
Status: COMPLETED
Conditions: Multinodular Goiter
Interventions: OTHER: Placebo|DRUG: MRrhTSH|DRUG: MRrhTSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Semaglutide Administered Subcutaneously Once Daily to Semaglutide Administered Subcutaneously Once Weekly
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural Lesotho
Status: COMPLETED
Conditions: HIV/AIDS|Tuberculosis|Diabetes Mellitus|Arterial Hypertension
Interventions: OTHER: Door-to-door|OTHER: Pitso
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Breast Cancer|Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin in the Treatment of Multiple Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: connective tissue graft|PROCEDURE: platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education Given to Postpartum Women on Their Attitudes Towards Childhood Vaccinations and Breastfeeding
Status: COMPLETED
Conditions: Breast Feeding|Vaccination Refusal|Training Group, Sensitivity
Interventions: BEHAVIORAL: training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Early Bactericidal Activity Safety Pulmonary Tuberculosis Pyrifazimine (TBI-166)
Status: UNKNOWN
Conditions: Sensitive Pulmonary Tuberculosis
Interventions: DRUG: Pyrifazimine (TBI-166)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant
Status: COMPLETED
Conditions: Uncontrolled Gout|Kidney Transplant
Interventions: BIOLOGICAL: Pegloticase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spatial-Motor Stroke-Rehab Study
Status: RECRUITING
Conditions: Spatial Neglect|Stroke
Interventions: DEVICE: Prism adaptation therapy (PAT) + Electrical stimulation (E-stim)|DEVICE: Prism adaptation therapy (PAT) + Sham Stimulator|OTHER: Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Twelve-year Follow-up on the Treatment of Obese Pregnant Women (TOP) Study
Status: RECRUITING
Conditions: Obesity|Lifestyle, Healthy|Diet, Healthy|Follow-up|Physical Activity|Body Composition|Gestational Weight Gain
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MNK Therapy in Releasing the Superficial Fascia for Patients With AAS: an Assessor-blinded, Randomised Controlled Trial
Status: RECRUITING
Conditions: Acute Ankle Sprain
Interventions: PROCEDURE: MNK therapy to release the superficial fascia|PROCEDURE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Measurements of Interface Pressures Between Two Pressure-ulcer Prevention Mattresses: Softform Premier and Airsoft Duo
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Airsoft Duo mattress|DEVICE: Softform Premier mattress (in static mode)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: prednisone plus cyclophosphamide|DRUG: Prednisone alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQA3526 in the Treatment of Primary Biliary Cirrhosis (PBC)
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: TQA3526|DRUG: Placebo to match TQA3526
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegfilgrastim as Support to Pediatric Sarcoma Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Sarcoma|Neutropenia
Interventions: DRUG: pegfilgrastim|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Axillary Access vs Standard Fluoroscopic Technique for Cardiac Lead Implantation: ZEROFLUOROAXI TRIAL
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Venous Puncture|Implantable Defibrillator User|Pacemaker Complication|Vascular Access Complication|Fluoroscopy; Adverse Effect
Interventions: PROCEDURE: Ultrasound Guided Axillary Venous Access|PROCEDURE: Fluoroscopy-Guided Axillary Venous Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABNCoV2 Vaccine in Adult Subjects Previously Vaccinated for SARS-CoV-2
Status: COMPLETED
Conditions: COVID-19 Disease
Interventions: BIOLOGICAL: ABNCoV2|BIOLOGICAL: Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
Status: RECRUITING
Conditions: Colorectal Cancer|Pancreatic Cancer|Gastric Cancers|Cholangiocarcinoma
Interventions: DRUG: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Expansion)|DRUG: BOLD-100 in combination with FOLFOX Chemotherapy (Dose Escalation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Versus Intravenous Cisplatin, Combined With Radiation, for Oral Cavity and Oropharynx Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Intra-arterial cisplatin|DRUG: Intravenous cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Analgesia to Prevent Pain in Patient Undergoing Removal of the Uterus Through Vaginal Route
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Exposure to Toxicants From Smoking and Vaping
Status: NOT_YET_RECRUITING
Conditions: Smoking, Tobacco|Vaping|Mental Health Disorder
Interventions: OTHER: Exclusive tobacco smoking|OTHER: Exclusive e-cigarette use|OTHER: Dual use of e-cigarettes and tobacco smoking|OTHER: No use of e-cigarettes or tobacco smoking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interferon-gamma or Aldesleukin and Vaccine Therapy in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: idiotype-pulsed autologous dendritic cell vaccine APC8020|BIOLOGICAL: recombinant interferon gamma|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Subacute Effect of Pharyngeal Pharmacological Sensory Stimulation in Elderly Patients With Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Oropharyngeal Dysphagia|Dysphagia|Swallowing Disorder
Interventions: OTHER: Capsaicin 10microM (TRPV1 natural agonist)|OTHER: Piperine 150microM (TRPV1 & TRPA1 natural agonist)|OTHER: Cinnamaldehyde 756,6microM + zinc 70microM (TRPA1 natural agonist)|OTHER: Citric acid 457,5microM (pH=3,5) (ASIC3 natural agonist)|OTHER: Capsaicin 10microM + Citric acid 457,5microM (pH=3,5) (TRPV1 & ASIC3 natural agonists)|OTHER: Placebo (Methyl benzoate, Propyl benzoate, Propylenglycol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate and Compare the Efficacy and Safety of Alectinib Versus Crizotinib and to Evaluate the Pharmacokinetics of Alectinib in Asian Participants With Treatment-Naive Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Lymphoma Kinase-positive Non-small Cell Lung Cancer
Interventions: DRUG: Alectinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zmax Compared to Augmentin in Sinusitis
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: Azithromycin Extended Release|DRUG: Amoxicillin/Clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacity of Hemodiafiltration Versus Hemofiltration for Renal Insufficiency During Intensive Care
Status: COMPLETED
Conditions: Renal Failure, Acute
Interventions: PROCEDURE: Hemodiafiltration first|PROCEDURE: Hemofiltration first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whey and Casein on IGFs in Prepubertal Boys
Status: UNKNOWN
Conditions: Metabolic Syndrome|Obesity
Interventions: BEHAVIORAL: Whey without milk minerals|BEHAVIORAL: Whey with milk minerals|BEHAVIORAL: Casein without milk minerals|BEHAVIORAL: Casein with milk minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: SNS-301 Monotherapy in High Risk MDS and CMML
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: SNS-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barrier Film vs. Standard Skin Care in Preventing Dermatitis in Women With Breast Cancer Receiving Radiation
Status: COMPLETED
Conditions: Breast Cancer|Dermatitis
Interventions: DEVICE: 3M Cavilon No Sting Barrier Film|DRUG: Standard Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes
Status: SUSPENDED
Conditions: Ischemic Stroke
Interventions: DRUG: TF0023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of Treatment With Atogepant 60 mg Daily for the Prevention of Migraine in Participants With Episodic Migraine
Status: COMPLETED
Conditions: Episodic Migraine
Interventions: DRUG: Standard of Care (SOC) Migraine Preventive Medication|DRUG: Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation.
Status: COMPLETED
Conditions: Chronic Constipation, Methanogenesis
Interventions: DRUG: Lubiprostone|DRUG: Lubiprostone Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients
Status: RECRUITING
Conditions: Larynx Cancer|Laryngectomy; Status
Interventions: DEVICE: High - speed video endoscopy (HSV)|DEVICE: Acoustic voice analysis|BEHAVIORAL: Quality of life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Efficacy and Safety of Prevention of Infection Foley Catheter as Compared to Conventional Foley Catheter
Status: UNKNOWN
Conditions: Urological Disease|Radical Cystectomy
Interventions: DEVICE: Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osteopathic Health Outcomes in Chronic Low Back Pain (OSTEOPATHIC) Trial
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: A. Active OMT and active UST|PROCEDURE: B. Sham OMT and active UST|PROCEDURE: C. Active OMT and sham UST|PROCEDURE: D. Sham OMT and sham UST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: liposomal lactoferrin|DRUG: SOC therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Testing Among Home Health Patients
Status: COMPLETED
Conditions: Adverse Drug Events|Adverse Drug Reactions|Drug Interaction Potentiation|Drug Metabolism, Poor, CYP2D6-RELATED|Drug Metabolism, Poor, CYP2C19-RELATED|Cytochrome P450 Enzyme Deficiency|Cytochrome P450 CYP2D6 Enzyme Deficiency|Cytochrome P450 CYP2C9 Enzyme Deficiency|Cytochrome P450 CYP2C19 Enzyme Deficiency|Cytochrome P450 CYP3A Enzyme Deficiency|Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant|Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant|Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
Interventions: GENETIC: Pharmacogenetic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Postoperative Bleeding in Subcapital Femoral Fractures
Status: COMPLETED
Conditions: Hip Fracture|Blood Loss
Interventions: DRUG: Tranexamic Acid|DRUG: Fibrin glue|PROCEDURE: Electrocauterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Evaluating Dual Inhibitor of PAK4 and NAMPT ATG-019 in Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Solid Tumor, Non-Hodgkin's Lymphoma
Interventions: DRUG: ATG-019|COMBINATION_PRODUCT: ATG-019 + Niacin ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Tolerability of the Addition of AVANDIA to Submaximal Doses of Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
Status: RECRUITING
Conditions: Muscle Spasticity|Hypertonia, Muscle|Cerebral Palsy|Multiple Sclerosis|Stroke|Hereditary Spastic Paraplegia|Dystonia|Spinal Cord Injuries
Interventions: DRUG: MTR-601
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Corticosteroid Intra-articular Injection in Hands Osteoarthritis
Status: COMPLETED
Conditions: Hands Osteoarthritis
Interventions: DRUG: Intra-articular injection with corticosteroid|DRUG: Intra-articular injection with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial
Status: COMPLETED
Conditions: Pregnancy|Induced Labor|Cervical Ripening
Interventions: DRUG: low dose oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of a Basiliximab, Mycophenolate Mofetil, Cyclosporine Microemulsion and Prednisone Combination Treatment Regimen in Pediatric Renal Allograft Recipients
Status: COMPLETED
Conditions: Pediatric Kidney Transplantation
Interventions: DRUG: basiliximab, MMF(mycophenolate mofetil), cyclosporine, prednisone (or equivalent)|DRUG: MMF, cyclosporine, steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy and Safety of MEDI4893
Status: COMPLETED
Conditions: Staphylococcus Aureus Pneumonia
Interventions: DRUG: MEDI4893|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hepatic Artery Infusion Chemotherapy (HAIC) Plus Durvalumab for Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic artery infusion chemotherapy（HAIC）|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib-based GVHD Prophylaxis After Allogeneic Transplant for Patients Without Matched Related Donors
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndrome
Interventions: DRUG: Bortezomib|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of Atorvastatin and Dexamethasone on Treatment for Chronic Subdural Hematoma in the Patients With Coagulation Disorders
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Oral Ulceration Healing in Patients Wearing a Removable Denture
Status: COMPLETED
Conditions: Oral Mucosa; Ulcer
Interventions: DRUG: Chlorhexidine Gluconate|DRUG: Choline Salicylate 8.7 % Oral Gel|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo Investigations
Status: COMPLETED
Conditions: Drug Effect|Drug Effect Prolonged
Interventions: DRUG: Niosomal PPE oromucoadhesive film|DRUG: Oromucoadhesive film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Replacing Red Meat With Legumes on Biomarkers of Chronic Diseases in Healthy Men (Leg4Life)
Status: UNKNOWN
Conditions: Colorectal Cancer|Cardiovascular Diseases|Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Partial replacement of red meat with legume-based foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Therapeutical Role of Continuous Intra-femoral Artery Infusion of Urokinase on Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: continuous intra-femoral thrombolysis group|DRUG: Conventional therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Hematologic Neoplasms|Neutropenia|Anemia|Thrombocytopenia|Infections|Bleeding
Interventions: BIOLOGICAL: umbilical cord derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Preoperative Oral Immunonutrition in Major Vascular Surgery
Status: COMPLETED
Conditions: Undernutrition
Interventions: DIETARY_SUPPLEMENT: Impact|DIETARY_SUPPLEMENT: Oral Impact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK127 in Combination With AK104 in Advanced and Metastatic Solid Tumours
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumours
Interventions: DRUG: AK127|DRUG: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis|Whooping Cough
Interventions: BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed Formulation 1|BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed, Formulation 2|BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed, Formulation 3|BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed, Formulation 4|BIOLOGICAL: Licensed Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed|BIOLOGICAL: Licensed Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety of Topical Insulin Drops for Open-angle Glaucoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma
Interventions: DRUG: Topical insulin (4 units)|DRUG: Topical insulin (20 units)|DRUG: Artificial tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVID
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Acute COVID-19 Syndrome|Long COVID|Long Covid19|COVID-19 Recurrent|Post-Acute COVID-19|Post-Acute COVID-19 Infection|SARS-CoV2 Infection|Post Acute Sequelae of COVID-19|Dysautonomia|Dysautonomia Like Disorder|Dysautonomia Orthostatic Hypotension Syndrome|Post COVID-19 Condition|Post-COVID Syndrome|Post COVID-19 Condition, Unspecified|Post-COVID-19 Syndrome
Interventions: DRUG: stellate ganglion block with 0.5% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Morphogenetic Protein-2 In Grade II Furcation Defects.
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: RhBMP-2 absorbable sponge in grade II furcation|PROCEDURE: PLATELET RICH FIBRIN in grade II furcation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Trabeculectomy: A Study in Germany
Status: UNKNOWN
Conditions: Open-angle Glaucoma
Interventions: DEVICE: Use of ologen Collagen Matrix in trabeculectomy|DRUG: Use of Mitomycin-C in trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia|Pulmonary Hypoplasia
Interventions: DEVICE: GoldBAL2 Detachable Balloon and BALTACCIBDPE100 Delivery Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of iStent to Laser in Exfoliation Glaucoma Helsinki Study Group
Status: RECRUITING
Conditions: Exfoliation Glaucoma|Cataract
Interventions: PROCEDURE: iStent|PROCEDURE: SLT-laser|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: LOKELMA 5 GM Powder for Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Experimental 1|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Clinical Application of [18F]RCCB6 and [68Ga]Ga-NOTA-RCCB6 PET/CT Imaging in the Diagnosis of CD70-expressing Multiple Tumors
Status: RECRUITING
Conditions: Kidney Cancer|Lymphomas|Positron Emission Tomography
Interventions: RADIATION: [18F]RCCB6 and [68Ga]Ga-NOTA-RCCB6 PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimised Early Management of Squamous Cell Carcinoma of the Head and Neck Cancer
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: OTHER: optimised management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Calculus Bovis Sativus (CBS) for Idiopathic Inflammatory Demyelinating Disease (CBSinIIDD)
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Inflammatory Demyelinating Disease|Multiple Sclerosis|Neuromyelitis Optica Spectrum Disorder|Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease|Acute Disseminated Encephalomyelitis
Interventions: DRUG: Calculus bovis sativus (CBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel or Paclitaxel in Treating Women With Unresectable Locally Advanced or Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Survival Benefit of Elective Neck Dissection in T1,2N0M0 Oral Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Oral Squamous Cell Carcinoma
Interventions: PROCEDURE: elective neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioenergetic Effects of Aging and Menopause (BEAM)
Status: RECRUITING
Conditions: Menopause|Obesity, Abdominal|Aging|Weight Gain
Interventions: DRUG: GnRH antagonist|DRUG: Estrogen Product|DRUG: Placebo estradiol|DRUG: Placebo GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Thienorphine Hydrochloride Tablets in Relapse Prevention Treatment of Opioid Dependence
Status: UNKNOWN
Conditions: Opioid Dependence
Interventions: DRUG: 0.2mg group|DRUG: 0.5mg group|DRUG: placebo control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergies
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: 0.15% azelastine hydrochloride|DRUG: 0.1% azelastine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preemptive Levator Ani Injections on Pain After Pelvic Reconstructive Surgery
Status: UNKNOWN
Conditions: Pelvic Floor Prolapse|Surgery|Pain, Postoperative
Interventions: PROCEDURE: Pelvic floor injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Thrombectomy of Medium Sized Vessels "M2 of MCA".
Status: UNKNOWN
Conditions: Stroke, Acute Ischemic
Interventions: DRUG: Mechanical thrombectomy|DRUG: medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Availability of COVID-19 Testing on Choice to Isolate and Socially Distance
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Positive COVID Test Result - Hypothetical Scenario|BEHAVIORAL: Negative COVID Test Result - Hypothetical Scenario|BEHAVIORAL: Unavailable COVID Test Result - Hypothetical Scenario
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Minimum Current for Train-of-four Monitoring
Status: COMPLETED
Conditions: Anesthesia|Anesthesia Recovery Period|Neuromuscular Blockade
Interventions: DEVICE: Train-of-four (TOF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Acute Psychobiological Responses to Laboratory Stress Tests
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: MMST|BEHAVIORAL: TSST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endovascular Therapy in Patients With Acute Deep Vein Thrombosis
Status: COMPLETED
Conditions: Acute Deep Venous Thrombosis
Interventions: DEVICE: Mechanical / pharmacomechanical thrombectomy plus local catheter directed thrombolysis|DEVICE: Local catheter directed thrombolysis alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of MEDI7510 in Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: MEDI7510|BIOLOGICAL: IIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Lactobacillus Delbruckii Lactis DN111244 Fermented Milk Consumption on Plasma Lipids Levels in Hypercholesterolaemic Adults
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: 1- Low fat drinkable fermented by Lactobacillus Delbruckii lactis (DN111244) - >10E8 <5.10E9 cfu/mL|DIETARY_SUPPLEMENT: 2- Low fat drinkable fermented by S. thermophilus and L. bulgaricus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE