pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SpO2 Accuracy In Vivo Testing for Neonates & Infants
Status: WITHDRAWN
Conditions: Pulse Oximetry
Interventions: DEVICE: MEDLINE RENEWAL PULSE OXIMETRY SENSORS|DEVICE: Reference CO-oximetry sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating a Pharmacokinetic Drug Interaction Between Amlodipine/Losartan and Rosuvastatin
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: amosartan|DRUG: rosuvastatin|DRUG: amosartan and rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Rehabilitation After Acute Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism
Interventions: BEHAVIORAL: Daily Activity Text|BEHAVIORAL: Control Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: AML With Gene Mutations
Interventions: DRUG: ZE46-0134
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of FOLFOXIGIL Versus FOLFOXIRI as First-line Therapy in Patients With mCRC
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Levoleucovorin|DRUG: 5-FU|DRUG: GM-CSF|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin in Infants With Hypoxic Ischemic Encephalopathy (HIE)
Status: COMPLETED
Conditions: Hypoxic Ischemic Encephalopathy
Interventions: DRUG: Human recombinant erythropoietin|PROCEDURE: EEG and Brain MRI|BIOLOGICAL: Nitric oxide measurement in the blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Setanaxib in Patients With Alport Syndrome
Status: RECRUITING
Conditions: Alport Syndrome
Interventions: DRUG: Setanaxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Ceasing of Colchicine Therapy in Familial Mediterranean Fever (FMF) Patients With Single MEFV (Mediterranean Fever) Gene Mutation
Status: UNKNOWN
Conditions: Familial Mediterranean Fever
Interventions: OTHER: Colchicine Cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy Pathways in the Treatment of Hormone Naïve Prostate Cancer Patients With and Without Comorbidities Treated With Degarelix or Luteinizing-Hormone-Releasing-Hormone (LHRH) Agonists.
Status: COMPLETED
Conditions: Advanced Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: LHRH agonist (Leuprorelinacetat, Goserelinacetat, Buserelinacetat, Triptorelinacetat)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atrial Fibrillation Ablation and Autonomic Modulation Via Thorascopic Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Totally Thoracoscopic PV isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Kabat Rehabilitation Technique Versus Conventional Physical Therapy in Treatment of Bell's Palsy
Status: NOT_YET_RECRUITING
Conditions: Bell's Palsy
Interventions: BEHAVIORAL: kabat technique for rehabilitation of facial palsy|DEVICE: electrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of H-reflex After Application of Electric Currents in Healthy People
Status: UNKNOWN
Conditions: Spasticity
Interventions: DEVICE: Transcutaneous Electrical Stimulation|DEVICE: 10Kilohertz (KHz)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human (FIH) Trial of 1A46 in Subjects With Advanced CD20 and/or CD19 Positive B-cell Hematologic Malignancies
Status: RECRUITING
Conditions: Non-Hodgkin's Lymphoma (Disorder)|Acute Lymphoid Leukemia, Disease (Disorder)
Interventions: DRUG: 1A46 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
Status: UNKNOWN
Conditions: Dental Caries|Secondary Dental Caries
Interventions: PROCEDURE: Three adhesive coats|PROCEDURE: Two adhesive coats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoadsorption in Anti-GBM Glomerulonephritis.
Status: COMPLETED
Conditions: Anti-glomerular Basement Membrane Glomerulonephritis
Interventions: DEVICE: Immunoadsorption (Immunosorba)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remifentanil on Hemodynamic Stability During Placement of a Mayfield Head Fixation Device for Craniotomy
Status: TERMINATED
Conditions: Surgery
Interventions: DRUG: Remifentanil|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pressure-dependent Changes in Hematocrit and Plasma Volume During Anesthesia
Status: UNKNOWN
Conditions: Blood Pressure|Hematocrit Change|Anesthesia
Interventions: PROCEDURE: Maintained blood pressure|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.
Status: WITHDRAWN
Conditions: Corneal Injuries
Interventions: DEVICE: Eyeprotx™ General Anesthesia Protective Goggles|DEVICE: Eyelid Tape|DEVICE: Eye Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The T-REX Trial: Tailored Regional External Beam Radiotherapy in Clinically Node-negative Breast Cancer Patients With 1-2 Sentinel Node Macrometastases.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: De-escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: Cantharidin|BIOLOGICAL: Lipopolysaccharide|BIOLOGICAL: Granulocyte-Macrophage Colony-Stimulating Factor|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)
Status: COMPLETED
Conditions: Analgesia, Epidural|Instrumental Delivery|Maternal Outcome|Neonatal Outcome
Interventions: DRUG: Ropivacaine/ Sufentanil according to local hospital protocol|OTHER: Care-as usual pain treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of a Smartphone Application to Increase Adherence to Medical Treatment in Patients With an Acute Coronary Syndrome.
Status: UNKNOWN
Conditions: Adherence, Medication
Interventions: DEVICE: Cell phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: DRUG: chlorambucil, tablets|DRUG: ofatumumab (GSK1841157) infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Sling Allograft (UVT) for the Treatment of Urinary Incontinence in Women Presenting With Synthetic Sling Complications
Status: COMPLETED
Conditions: Female Stress Incontinence|Stress Urinary Incontinence
Interventions: BIOLOGICAL: UVT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnetic Stimulation of the Dorsal Spinal Cord on Gait in Patients With Parkinson´s Disease and Deep Brain Stimulation
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Magnetic transcutaneous spinal cord stimulation|DEVICE: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of PAP Therapy on Reducing AF Recurrence in Patients With Morbidity of OSA
Status: UNKNOWN
Conditions: Atrial Fibrillation|Obstructive Sleep Apnea
Interventions: DEVICE: PAP therapy with telemonitoring|OTHER: AF standard management and OSA general care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safer Storage Safer Homes An Inpatient Pediatric Lethal Means Counseling Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Firearm Injury|Hospitalizations Psychiatric
Interventions: BEHAVIORAL: Guardians receiving counseling + lock
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of EMG-Directed Virtual-Reality Experience Training for Motor Stroke Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Stroke|Spinal Cord Injuries
Interventions: DEVICE: VR Intervention|DEVICE: FES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coordinated Oral Health Promotion (CO-OP) Chicago
Status: COMPLETED
Conditions: Dental Caries in Children|Health Behavior|Healthcare Disparities
Interventions: BEHAVIORAL: Community Health Worker (CHW) services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of the Oral Contraceptive Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.
Status: COMPLETED
Conditions: Female Contraception|Contraception|Therapeutic Equivalency|Pharmacokinetics
Interventions: DRUG: Norgestimate/Ehinyl Estradiol; Folic acid.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rupture of Thumb's Long Extensor Tendon After Fracture of the Distal Radius, Study of Muscle and Tendon Pathology
Status: ACTIVE_NOT_RECRUITING
Conditions: Distal Radius Fractures|Tendon Injury - Hand|Pathology
Interventions: PROCEDURE: Biopsy of EPL tendon and muscle during the operation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: Peposertib 50 mg|DRUG: Peposertib 100 mg|DRUG: Peposertib 150 mg|DRUG: Peposertib 250 mg|DRUG: Capecitabine|RADIATION: Radiotherapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib With Radiation Therapy in Patients With Inflammatory or Loco-regionally Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Veliparib|RADIATION: Standard radiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Itacitinib for the Treatment of Bronchiolitis Obliterans Syndrome After Donor Hematopoietic Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchiolitis Obliterans
Interventions: DRUG: Itacitinib|DRUG: Itacitinib Adipate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study Evaluating the Efficacy of a Wireless Vital Signs Monitor for Critically Ill Newborns in Kenya
Status: COMPLETED
Conditions: Newborn Morbidity|Newborn Complication
Interventions: DEVICE: neoGuard vital signs monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of the BlinkER System in Participants With Facial Nerve Palsy
Status: NOT_YET_RECRUITING
Conditions: Bell's Palsy|Ramsay Hunt Syndrome|Lyme Disease|Facial Palsy
Interventions: DEVICE: BlinkER device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Status: COMPLETED
Conditions: Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis|Spondylolisthesis|Spinal Fractures|Scoliosis or Tumors
Interventions: DEVICE: Philips Intelivue MP70 monitor|DEVICE: Pleth Variability Index (PVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Activation of Hip Muscles in Runners With Patellofemoral Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Therapy taping|OTHER: Placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Lumateperone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia|Colorectal Cancer|Fatigue|Quality of Life|Cognitive Impairment
Interventions: DIAGNOSTIC_TEST: iron deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Intracavitary Electrocardiographic System for Real-time Positioning Peripherally Inserted Central Catheter Tip
Status: COMPLETED
Conditions: Peripherally Inserted Central Catheter|Intracavitary Electrocardiogram Guiding
Interventions: DEVICE: ECG|PROCEDURE: Surface prediction length method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Called GUS to Understand How Much of the Contrast Agent Gadavist is Used and How Much is Wasted in Two Different Containers (Single-dose Vials and Imaging Bulk Packages ) in a Real-world Setting
Status: COMPLETED
Conditions: Contrast Enhancement in Magnetic Resonance Imaging
Interventions: DRUG: Gadobutrol (Gadavist/Gadovist, BAY86-4875)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Iptacopan (part 1)|DRUG: Iptacopan (part 2)|DRUG: Placebo + standard of care|DRUG: Iptacopan + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidative Effect of Plantago Asiatica L. Extract
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Plantago asiatica L. extract 5g|DIETARY_SUPPLEMENT: Plantago asiatica L. extract 10g|DIETARY_SUPPLEMENT: Plantago asiatica L. extract 20g|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bilioenteric Anastomosis by Magnetic Compressive Technique
Status: UNKNOWN
Conditions: Pancreatic Cancer|Cholangiocarcinoma|Bile Duct Injury|Choledochal Cyst|Biliary Calculi
Interventions: PROCEDURE: Magnetic Compressive Anastomosis|PROCEDURE: Manual Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Topical Treatment of Hand Dermatitis (Eczema)
Status: COMPLETED
Conditions: Contact Dermatitis|Eczema, Contact
Interventions: DEVICE: Epikeia Coatings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery
Status: COMPLETED
Conditions: Failed Moderate Sedation During Procedure
Interventions: DRUG: 1 mL/kg bupivacaine 0.25%.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Chemotherapy in Treating Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: dexamethasone|DRUG: fluorouracil|RADIATION: brachytherapy|RADIATION: phosphorus P32|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Exploratory Clinical Study of Bevacizumab Combined With Oxaliplatin and TAS-102 in First-line Treatment of Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Bevacizumab combined with Oxaliplatin and TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Inhalation on Mannitol Responsiveness
Status: COMPLETED
Conditions: Asthma
Interventions: PROCEDURE: Deep inhalation technique|PROCEDURE: Tidal breathing technique|DRUG: Methacholine|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interest of Ultrasonography in Electroneuromyography: Single-blind Randomised Controlled Clinical Trial
Status: COMPLETED
Conditions: Electromyoneurography
Interventions: OTHER: Electroneuromyography with ultrasound|OTHER: Electroneuromyography without ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Enstilar Foam in Combination With Apremilast (Otezla) in Patients With Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Enstilar|DRUG: Vehicle|DRUG: Otezla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FODMAPs and Refractory GERD
Status: COMPLETED
Conditions: Gastro-esophageal Reflux Disease (GERD)
Interventions: DIETARY_SUPPLEMENT: Low-FODMAP diet|DIETARY_SUPPLEMENT: GERD diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of Care
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: OTHER: Quality of Life (QOL) questionnaires|OTHER: Healthcare Resource Utilization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Activity Drop-out Ratio in Patients Living With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Adherence, Patient|Physical Inactivity
Interventions: BEHAVIORAL: Socioecological model apply to reduce physical activity drop out in type 2 diabetes patients|BEHAVIORAL: Nordic Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars
Status: COMPLETED
Conditions: Cicatrix
Interventions: BIOLOGICAL: Mesenchyme Stem Cells low-dose group|BIOLOGICAL: Mesenchyme Stem Cells high-dose group|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture With Deqi And Psychological Effects in Treatment of Bell's Palsy
Status: COMPLETED
Conditions: Bell's Palsy
Interventions: DEVICE: acupuncture, deqi|DEVICE: acupuncture Non-manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Closed-loop Insulin Delivery System in Perioperative Diabetic Patients: an Open-label, Randomized Controlled Trial
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Hybrid Closed-loop Insulin Delivery System|DEVICE: Insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining the 'Sniffing Position" in Infants and Toddlers - A Pilot Study
Status: COMPLETED
Conditions: Airway Management|Infant ALL|Children, Only|Endotracheal Intubation
Interventions: PROCEDURE: Airway positioning per specified protocol followed by Direct Laryngoscopy and Endotracheal Intubation|PROCEDURE: Airway positioning per provider preference followed by Direct Laryngoscopy and Endotracheal Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study
Status: COMPLETED
Conditions: Primary Immunodeficiency (PID)|Secondary Immunodeficiency (SID)|Neurological Autoimmune Disease
Interventions: OTHER: Immunoglobulin G (IgG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Examine the Cytokine Levels, Gene Expression and Safety of a Single Nasal Dose of JNJ-43260295, in Healthy Participants, and Atopic Participants With Mild to Mild-Persistent Asthma
Status: TERMINATED
Conditions: Healthy|Asthma
Interventions: DRUG: JNJ-43260295|DRUG: Placebo|DRUG: Nasal Allergen Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Interventions to Mitigate Neurodevelopmental Risk
Status: TERMINATED
Conditions: Child Development|Mother-Infant Interaction|Diabetes Mellitus, Gestational
Interventions: BEHAVIORAL: Family Nurture Intervention (FNI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evolution of Adipokines and Body Composition in Rheumatoid Arthritis Patients Receiving Tocilizumab Therapy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment
Status: UNKNOWN
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: DIAGNOSTIC_TEST: Treatment-specific InSight|DIAGNOSTIC_TEST: InSight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia of Newborn
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Early Diffuse Cutaneous Systemic Sclerosis
Status: COMPLETED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Pediatric Pulmonary Vein Stenosis Outcomes Using Data Acquired During a Cardiac Catheterization
Status: RECRUITING
Conditions: Pulmonary Vein Stenosis
Interventions: DIAGNOSTIC_TEST: Standardized catheterization assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of Algometry for Use in the Human Foot
Status: UNKNOWN
Conditions: Normative Algometric Pressures|Foot Pain
Interventions: DEVICE: Algometric meter readings for perception of pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Fe Absorption From Iron Salt in Milk
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Iron fortified milk with iron salt labelled with 58Fe and 57Fe|OTHER: Iron fortified milk with iron salt labelled with 58Fe and 57Fe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Assessment of Beltavac® With Polymerized Extract of HDM
Status: RECRUITING
Conditions: House Dust Mite Allergy
Interventions: BIOLOGICAL: House dust mites allergoid from Dermatophagoides pteronyssinus and Dermatophagoides farinae|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Neuroprotection of Remote Ischemic Preconditioning (RIPC) on Cardiac Surgery in Multicenter
Status: UNKNOWN
Conditions: Cardiac Surgery Patients
Interventions: PROCEDURE: RIPC|PROCEDURE: sham RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CAR T Cell Therapy Related Cardiovascular Outcomes
Status: COMPLETED
Conditions: Cardiovascular Diseases|B-cell Acute Lymphoblastic Leukemia|B-cell Lymphoma Refractory|B-cell Lymphoma Recurrent|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|Diffuse Large B Cell Lymphoma|Cardiotoxicity|Cardiovascular Complication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Seizure
Interventions: DRUG: levetiracetam|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trail of Sperstent® Used for Residual Lesions of Femoropopliteal Arteries
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Stenosis|Dissection
Interventions: DEVICE: Sperstent® peripheral spot stent system|DEVICE: Everflex® self-expanding peripheral stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota and Protein-energy Wasting (MIDIWA)
Status: COMPLETED
Conditions: Undernutrition
Interventions: DIETARY_SUPPLEMENT: Branched chain amino acids (BCAA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Advanced Colorectal Cancer|Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: DRUG: ABT-869|DRUG: bevacizumab|DRUG: oxaliplatin|DRUG: folinic acid|DRUG: fluorouracil|DRUG: ABT-869
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Transcranial Direct Current Stimulator (TDCS)|DEVICE: Control Group|OTHER: Healthy Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery
Status: COMPLETED
Conditions: Parotid Neoplasm|Thyroid Neoplasms|Head and Neck Neoplasms|Surgery|Nerve Injury|Imaging
Interventions: DRUG: ALM-488
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Global Posture Re-education|OTHER: Active Cycle of Breathing Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ventilation Tubes Among Anesthetized Pediatrics
Status: WITHDRAWN
Conditions: Pulmonary Ventilation
Interventions: DEVICE: Ventilator breathing tube F2220|DEVICE: Ventilator breathing tube F2216|DEVICE: Ventilator breathing tube F1520|DEVICE: Ventilator breathing tube F1516|DEVICE: Ventilator breathing tube U1016|DEVICE: Ventilator breathing tube U1516|DEVICE: Ventilator breathing tube CA20|DEVICE: Ventilator breathing tube CA16
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long Term Safety Study of Levalbuterol and Racemic Albuterol in Subjects Twelve Years of Age and Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: levalbuterol tartrate HFA MDI|DRUG: racemic albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial in Adult Participants With Schizophrenia Treated Prospectively for 6-months With Abilify MyCite®
Status: TERMINATED
Conditions: Schizophrenia
Interventions: COMBINATION_PRODUCT: Abilify MyCite®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inspiratory Muscle Training and Pulmonary Function in Patients Submitted to Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery Candidate|Muscle Weakness|Complication,Postoperative|Respiratory Muscle
Interventions: DEVICE: Inspiratory muscle training - Powerbreath|OTHER: Aerobic exercise in cycle ergometer|OTHER: Deep breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label Pilot Study of Lenalidomide (Revlimid) as Adjuvant Treatment for Refractory Cutaneous T Cell Lymphoma
Status: UNKNOWN
Conditions: Cutaneous T Cell Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Visual Information Change in Functional Dystonia
Status: TERMINATED
Conditions: Dystonia|Dystonic Disorders|Torticollis|Movement Disorders|Central Nervous System Diseases|Nervous System Diseases|Dyskinesias|Neurologic Manifestations
Interventions: DEVICE: prism glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Contura™ Catheter in Intermediate-Risk, Pathological Stage 0, I, or II (Up to 3.0 cm) Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Contura catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Pathophysiology of Varicose Veins in Pregnancy
Status: COMPLETED
Conditions: Varicose Veins|Varicose Veins of Lower Limb|Chronic Venous Insufficiency|Varicose; Vessel
Interventions: DIAGNOSTIC_TEST: Advanced ultrasound measurements (Duplex ultrasound (DUS) and Vector flow imaging (VFI)|OTHER: Clinical interventions and procedures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)
Status: RECRUITING
Conditions: Radiotracer|Hypertension|Cholesterol
Interventions: DRUG: FNP-59
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-Escalation Study of Pixantrone Monotherapy in Pediatric Patients With Relapsed or Refractory Cancer
Status: WITHDRAWN
Conditions: Lymphoma|Solid Tumor (Excluding CNS)
Interventions: DRUG: Pixantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oculomotor Dysfunction Leading to Children Vertigo
Status: COMPLETED
Conditions: Vertigo|Headache|Anomaly of Vergence System|Accommodation Disorders|Orthoptic Rehabilitation
Interventions: PROCEDURE: orthoptic rehabilitation|OTHER: Orthoptic diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma|Brain Tumor
Interventions: OTHER: Control Group - Standard of care neurosurgical resection|PROCEDURE: MRF/MRI infiltration guidance for extended resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DRUG: RTX-GRT7039
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-Month Study to Evaluate the Efficacy and Safety of Once-Daily Instillation of Combination Glaucoma Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-angle|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/Timolol maleate 0.5% ophthalmic solution|DRUG: Latanoprost 0.005%/Timolol 0.005% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pembrolizumab and Cisplatin on Metastatic, Locally Recurrent or Inoperable Triple-Negative Breast Cancer
Status: WITHDRAWN
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Metastatic Breast Cancer|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Triple Negative Breast Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Weight Bearing Thrust Manipulation With Non Weightbearing Thrust Manipulation in Patients With Forward Head Posture
Status: COMPLETED
Conditions: Cervical Pain
Interventions: OTHER: Thrust Manipulation (in weight bearing and non weight bearing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Microtenotomy for Treatment of Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: PROCEDURE: Arthroscopic acromioplasty|PROCEDURE: Microtenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Anterior Glenohumeral Dislocation in Ventral Decubitus Versus Dorsal Decubitus Under Procedural Sedation
Status: RECRUITING
Conditions: Reduction|Emergencies|Anterior Shoulder Dislocation
Interventions: PROCEDURE: reductions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma
Status: COMPLETED
Conditions: Exfoliation Syndrome|Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: AR-12286
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BUN/Cr-based Hydration Therapy to Improve Outcome of Patients With Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Dehydration|Ischemic Stroke
Interventions: DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Bladder Pressure With a Novel External Device, Comparison to Urodynamics Testing
Status: ENROLLING_BY_INVITATION
Conditions: Urinary Bladder, Neurogenic|Urodynamics
Interventions: DIAGNOSTIC_TEST: Urodynamics Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Lymphedema|Stage IA1 Cervical Cancer AJCC v6 and v7|Stage IA2 Cervical Cancer AJCC v6 and v7|Stage IB1 Cervical Cancer AJCC v6 and v7
Interventions: PROCEDURE: Conization|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Therapeutic Conventional Surgery|PROCEDURE: Therapeutic Lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of the In-utero Transmission of Probiotics
Status: COMPLETED
Conditions: In Utero Drug Exposure
Interventions: BIOLOGICAL: Natural products: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: IMC-3C5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant Versus Placebo Plus Fulvestrant in Chinese Men and Postmenopausal Women With Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Alpelisib|DRUG: Fulvestrant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent Emotion Coaching for Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Atypical Anorexia Nervosa
Interventions: BEHAVIORAL: Emotion Coaching|OTHER: Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma|Ovarian Cancer|Biliary Carcinoma|Colorectal Cancer
Interventions: DRUG: LOAd703
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ganaxolone in Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: Ganaxolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Possible Superiority Expressed by the Faster Onset of Action and the Efficacy and Safety of Sildenafil Citrate 20mg Sublingual Tablet in the Treatment of Erectile Dysfunction of Different Etiologies
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: Sildenafil Citrate 20mg Tablet Sublingual|DRUG: Viagra ® 50mg tablet Coated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354
Status: COMPLETED
Conditions: Asthma|Healthy
Interventions: BIOLOGICAL: CAT-354 150 mg (intravenous)|BIOLOGICAL: CAT-354 150 mg (subcutaneous)|BIOLOGICAL: CAT-354 300 mg (subcutaneous)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bacillus Coagulans and Galactomannans on Obese Patients Undergoing Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity|Quality of Life
Interventions: DIETARY_SUPPLEMENT: LactoWise®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Review of Trend in Incidence and Characteristics of Hospital-acquired Acute Kidney Injury in Hospital Selayang
Status: COMPLETED
Conditions: Acute Kidney Injury|Acute Renal Failure|Kidney Failure, Acute|Hospital Acquired Condition
Interventions: OTHER: No AKI|OTHER: CA-AKI|OTHER: HA-AKI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study of CNTO 136 in Patients With Active Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: CNTO 136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Stem Cell Therapy in Patients With Acute Burn
Status: UNKNOWN
Conditions: Burns
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cells|BIOLOGICAL: human cord blood mononuclear cells and human umbilical cord mesenchymal stem cells|DRUG: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Receptors, Estrogen|Genes, Erbb-2|Breast Neoplasms
Interventions: DRUG: Palbociclib (75, 100, 125 milligram [mg])|DRUG: H3B-6545 (150, 300, 450 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT