pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Tolerability and Immunogenicity Study of 2 Dose Levels of Trimeric Glycoprotein140 (gp140) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: gp140, 50 mcg|BIOLOGICAL: gp140, 50 mcg + Adjuvant|BIOLOGICAL: gp140, 250 mcg|BIOLOGICAL: gp140, 250 mcg + Adjuvant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neural Control of Non-invasive Ventilation in the Preterm
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn|Infant, Premature
Interventions: DEVICE: Neurally Controlled Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph 3 ADI-PEG 20 Versus Placebo in Subjects With Advanced Hepatocellular Carcinoma Who Have Failed Prior Systemic Therapy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ADI-PEG 20 (arginine deiminase formulated with polyethylene glycol)|DRUG: Placebo|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Psilocybin in Concussion Headache
Status: TERMINATED
Conditions: Post-Traumatic Headache
Interventions: DRUG: Placebo oral capsule|DRUG: Low Dose Psilocybin|DRUG: High Dose Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dec+Flu+Bu Conditioning Regimen for Elderly AML in CR Undergoing Allo-HSCT
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Allogeneic Hematopoietic Stem Cell Transplantation|Conditioning|Elderly
Interventions: DRUG: Decitabine|DRUG: Busulfan (BU)|DRUG: Fludarabine(Flu)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transthoracic Sonography Versus High Resolution Computed Tomography in Alveolar Intersitial Syndrome
Status: UNKNOWN
Conditions: Pleural Diseases
Interventions: OTHER: High resolution computed tomography|OTHER: trans thoracic ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Adenocarcinoma|Metastatic HER2-Positive Breast Carcinoma|Recurrent Breast Adenocarcinoma|Recurrent HER2-Positive Breast Carcinoma|Stage III Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Unresectable Breast Carcinoma|Unresectable HER2-Positive Breast Carcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Docetaxel|PROCEDURE: Magnetic Resonance Imaging|DRUG: Paclitaxel|BIOLOGICAL: Pertuzumab|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Combined With Toripalimab and AG Regiments for First-line Treatment of Unresectable or Relapsing Metastatic Ampullary Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Ampullary Carcinoma
Interventions: DRUG: Surufatinib+Toripalimab+AG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Saxagliptin on Adipose Tissue Inflammation in Humans
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing Loss
Status: NOT_YET_RECRUITING
Conditions: Age-related Hearing Loss|Cognitive Decline|Loneliness|Social Isolation
Interventions: BEHAVIORAL: Auditory-cognitive dual-task training (ACDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics Study in Adults for the Prevention of S. Epidermidis Infection in Low Birth Weight Infants
Status: COMPLETED
Conditions: Staphylococcal Sepsis
Interventions: DRUG: Placebo|DRUG: BSYX-A110|DRUG: BSYX-A110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Dual Therapy for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in Adults
Status: COMPLETED
Conditions: Atopic Dermatitis|Pruritus
Interventions: DEVICE: RD047-26
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk
Status: ACTIVE_NOT_RECRUITING
Conditions: Resectable Soft Tissue Sarcoma|Stage I Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8|Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Interventions: RADIATION: Hypofractionated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Results of a Randomized Trial Comparing Banded-versus-Standard Laparoscopic Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Banded Laparoscopic Roux-en-Y gastric bypass|PROCEDURE: Unbanded Laparoscopic Roux- en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANS Effects of ULF-TENS Stimulation in Patients With and Without TMD
Status: UNKNOWN
Conditions: TEMPOROMANDIBULAR JOINT DISEASES
Interventions: DEVICE: ULF TENS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study To Determine The Effect Of Food And Strong CYP3A4 Enzyme Inhibitor On PF-04449913 Drug Levels
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04449913, ketoconazole|DRUG: PF-04449913, ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-Angle Glaucoma Subjects With Cataract Treated With Cataract Surgery Plus One iStent and One iStent Supra
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: Cataract surgery plus one iStent and one iStent Supra implanted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [S,S]-Reboxetine Add-On Trial
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: [S,S]-Reboxetine + Pregabalin|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Voiding After Gynecological Surgery Trial
Status: TERMINATED
Conditions: Urinary Retention|Postoperative Complications|Surgery
Interventions: PROCEDURE: Retrograde bladder filling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Remote Ischemic Preconditioning on Lung Injury After Pulmonary Resection
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: PROCEDURE: remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pycnogenol® on ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DIETARY_SUPPLEMENT: Pycnogenol|DRUG: Methylphenidate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Cryotherapy for Skin Anesthesia During Arterial Puncture
Status: COMPLETED
Conditions: Cryotherapy Effect
Interventions: DEVICE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovicidal Efficacy and Safety of Abametapir Lotion 0.74% Administered for the Treatment of Head Lice Infestation
Status: COMPLETED
Conditions: Head Lice Infestation
Interventions: DRUG: Abametapir Lotion 0.74% w/w|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-68284528 Out-of-Specification (OOS) for Commercial Release in Participants With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Cilta-cel|DRUG: Lymphodepleting Therapy (Cyclophosphamide and Fludarabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: AK117|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Status: RECRUITING
Conditions: Low-grade Glioma|Advanced Solid Tumor
Interventions: DRUG: DAY101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD30 CAR for CD30+ NSGCT
Status: RECRUITING
Conditions: Germ Cell Tumor|Nonseminomatous Germ Cell Tumor
Interventions: BIOLOGICAL: ATLCAR.CD30 Cells|DRUG: Cyclophosphamid|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery.
Status: RECRUITING
Conditions: Nutraceuticals
Interventions: DIETARY_SUPPLEMENT: Betalain-rich concentrate (AltRed)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study to Evaluate MEDI-534 in Children 6 to < 24 Months of Age
Status: COMPLETED
Conditions: Respiratory Viral Infections|Respiratory Syncytial Virus Infections|Parainfluenza Virus 3, Human
Interventions: BIOLOGICAL: MEDI-534|BIOLOGICAL: MEDI-534|BIOLOGICAL: MEDI-534
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Folate From a Mixed Diet Using a Stable Isotope Method
Status: COMPLETED
Conditions: Folate Bioavailability|Healthy
Interventions: BEHAVIORAL: Controlled diet|BEHAVIORAL: folic acid supplement|BEHAVIORAL: 13C11-labelled folic acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants.
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacokinetics
Interventions: DRUG: DS-1971|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 6-Methyl-Prednisolone for Multiple Organ Dysfunction Syndrome
Status: UNKNOWN
Conditions: Multiple Organ Dysfunction Syndrome
Interventions: DRUG: 6-methyl-prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Obsessive Compulsive Disorder
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Continuous theta burst stimulation (cTBS)|DEVICE: shame rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tick-borne Illness and Clothing Study of Rhode Island
Status: COMPLETED
Conditions: Tick Bites|Tick-borne Diseases
Interventions: OTHER: Permethrin Impregnated Clothing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Comprehensive Geriatric Assessment and Laboratory Biomarkers in Elderly Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Plasma Cell Myeloma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Comprehensive Geriatric Assessment|OTHER: Electronic Health Record Review|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lycopene or Omega-3 Fatty Acid Nutritional Supplements in Treating Patients With Stage I or Stage II Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: lycopene supplement|DIETARY_SUPPLEMENT: fish oil supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Transversus Abdominis Plane Block After Groin Hernia Repair
Status: COMPLETED
Conditions: Hernia
Interventions: PROCEDURE: Transversus abdominis plane block|PROCEDURE: Saline|PROCEDURE: Local infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety of a Single Intravenous Infusion of MGAWN1 in Healthy Adults
Status: COMPLETED
Conditions: West Nile Virus
Interventions: DRUG: MGAWN1|DRUG: MGAWN1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MabionCD20 Compared to MabThera in Lymphoma Patients
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tivozanib Before Surgery in Treating Patients With Localized Kidney Cancer
Status: WITHDRAWN
Conditions: Stage II Renal Cell Cancer|Stage III Renal Cell Cancer
Interventions: DRUG: tivozanib|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Retinal Drusen|Age-related Macular Degeneration|Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Lumega-Z|DIETARY_SUPPLEMENT: AREDS2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of PGS2.0 in Patients With Unexplained RPL
Status: UNKNOWN
Conditions: Recurrent Pregnancy Loss|Infertility, Female
Interventions: PROCEDURE: IVF/ICSI|GENETIC: PGS 2.0|OTHER: Conventional embryo morphology evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Diaphragmatic Release on Upper Crossed Syndrome
Status: NOT_YET_RECRUITING
Conditions: Neck Muscle Issue|Kyphosis
Interventions: OTHER: effect of diaphragmatic release on upper crossed syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Proprioceptive Neuromuscular Facilitation and Mobilization In Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement|Subacromial Impingement Syndrome
Interventions: OTHER: Conventional Physiotherapy|OTHER: Shoulder Mobilization|OTHER: Proprioceptive Neuromuscular Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: New Heart Imaging Techniques to Evaluate Possible Heart Disease
Status: RECRUITING
Conditions: Healthy|Obesity|Diabetes|Healthy Volunteers|Atherosclerosis
Interventions: DEVICE: MR Imaging Techniques - 1|DEVICE: MR Imaging Techniques - 2|DEVICE: MR Imaging Techniques - 3|DEVICE: MR Imaging Techniques - 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Evaluation of the Esophagogastric Junction Exposure Obtained by the Flexible Liver Retractor in Gastroplasty
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: CONVENTIONAL LIVER RETRACTOR DEVICE|DEVICE: FLEXIBLE LIVER RETRACTOR DEVICE|PROCEDURE: LAPAROSCOPIC ROUX-EN-Y GASTRIC BYPASS SURGERY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Experience of Pain During Oocyte Retrieval- a Comparison Between Two Aspiration Needles
Status: COMPLETED
Conditions: Infertility
Interventions: DEVICE: Swemed Follicle Aspiration Set Reduced Single Lumen|DEVICE: Swemed Follicle Aspiration Set Single Lumen (1.4 mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study Assessing the Ability of an Insulin Pump-controlling Algorithm to Minimize Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Predictive Low Glucose Minimizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Undisplaced Femoral Neck Fractures
Status: COMPLETED
Conditions: Hip Fractures|Femoral Neck Fractures|Undisplaced Fracture|Internal Fixation; Complications|Arthroplasty Complications
Interventions: DEVICE: Internal fixation or hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Assess Chelation Therapy 2
Status: COMPLETED
Conditions: Diabetes|Myocardial Infarction
Interventions: DRUG: disodium EDTA|DIETARY_SUPPLEMENT: Oral Multi Vitamins/Minerals (OMVM)|DRUG: Placebo disodium EDTA|DIETARY_SUPPLEMENT: Placebo Oral Multi Vitamins/Minerals (OMVM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients
Status: UNKNOWN
Conditions: Dementia|Mild Cognitive Impairment|Cataract Senile|Cataract|Delirium in Old Age|Delirium Confusional State|Post-Op Complication|Cataract in Old Age
Interventions: DIAGNOSTIC_TEST: Visual Acuity|DIAGNOSTIC_TEST: CAM (Confusion Assesment Method)|DIAGNOSTIC_TEST: CATQUEST 9-SF|DIAGNOSTIC_TEST: OCT|DIAGNOSTIC_TEST: 6CIT|DIAGNOSTIC_TEST: Barthel Index|DIAGNOSTIC_TEST: Endothelial Microscopy - Cornea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Anatomical Classification of Portal Vein Location of Pancreas Tumors
Status: COMPLETED
Conditions: Pancreatic Neoplasm Malignant Head Primary
Interventions: PROCEDURE: primary repair|PROCEDURE: segmental resection|PROCEDURE: graft reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin for Relapsed/Refractory CD30-positive Non-Hodgkin Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety Study of MT-1303 in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: MT-1303
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone Treatment for Prolonged Grief Disorder (PGD)
Status: TERMINATED
Conditions: Prolonged Grief Disorder
Interventions: DRUG: Naltrexone HCl 50 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria
Status: COMPLETED
Conditions: Secondary Hyperoxaluria|Nephrolithiasis|Hyperoxaluria|Kidney Stones
Interventions: OTHER: Test Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Infant Egg Consumption on Child Health and Cognition Development
Status: COMPLETED
Conditions: Growth & Development|Obesity|Cardiovascular Risk Factor|Metabolic Syndrome|Food Allergy|Cognitive Developmental Delay
Interventions: OTHER: Infant egg consumption (i.e., age of introduction and frequency of intake)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beneficial Effects of an Integrated Program of Multicomponent Physical Exercise. Cohort Study
Status: WITHDRAWN
Conditions: Frailty|Geriatric Syndromes|Functional Recovery
Interventions: BEHAVIORAL: Multicomponent exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Absorption of Calcium Citrate and Calcium Carbonate in Patients With an RYGB, LSG, and OAGB
Status: NOT_YET_RECRUITING
Conditions: Calcium Citrate Absorption|Calcium Carbonate Absorption
Interventions: DRUG: The absorption effect between calcium citrate and calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SD-101, Nivolumab, and Radiation Therapy in Treating Patients With Chemotherapy-Refractory Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma|Refractory Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: BIOLOGICAL: Nivolumab|RADIATION: Radiation Therapy|DRUG: TLR9 Agonist SD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STS Administration on Coronavirus Disease (COVID-19) Patients in Critical Care
Status: RECRUITING
Conditions: COVID-19|Virus Diseases|Corona Virus Infection
Interventions: DRUG: Sodium Thiosulfate 25% Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single Surgeon, Randomized Control Study Comparing ab Interno XEN Gel Microstent Implantation vs Closed Conjunctiva ab Externo Implantation Performed at the Slit Lamp for the Treatment of Uncontrolled Glaucoma
Status: UNKNOWN
Conditions: The Objective of the Study is to Prospectively Compare the Success Rate of ab Externo and Interno Implantation
Interventions: DEVICE: XEN gel microstent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Alife Hera System as an Adjunctive Tool for the Prioritization of Embryos Deemed Suitable for Transfer
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility
Interventions: DEVICE: Hera Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Bioavailability Study of Lovastatin Tablets and Mevacor Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lovastatin 40 mg tablets|DRUG: Lovastatin (Mevacor®) 40 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer
Status: TERMINATED
Conditions: Early Breast Cancer (Phase 2)|Advanced Breast Cancer (Phase 1b)
Interventions: DRUG: PF-04691502|DRUG: PF-04691502 in combination with Letrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of AZD4041 in Healthy Participants
Status: COMPLETED
Conditions: Opioid Use Disorder (OUD)
Interventions: DRUG: AZD4041|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting
Status: TERMINATED
Conditions: Carotid Stenosis
Interventions: DEVICE: Carotid Stent Implantation|DEVICE: Embolic Protection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINAL
Status: COMPLETED
Conditions: Alport Syndrome
Interventions: DRUG: Placebo Oral Capsule|DRUG: Bardoxolone Methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the PK Profiles and Safety of CKD-385 in Healthy Volunteers Under Fed Conditions
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: CKD-385|DRUG: D744
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Augmented Reality Application Developed for ACLs Training on the Knowledge and Skill Levels of Nurses
Status: COMPLETED
Conditions: ACLs Learning
Interventions: DEVICE: An ACLs cart training course was developed using augmented reality (AR) technologies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effects of Bed Exercises on Anxiety, Pain, Early Ambulation and Mobilization in Patients Undergoing Major Surgery
Status: COMPLETED
Conditions: Surgery|Anxiety|Pain
Interventions: BEHAVIORAL: Turning in bed, arm and leg exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study of SPD489 Administered With Two Different Means of Administration in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lisdexamfetamine Dimesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Autologous Progenitor Cell Transplantation in Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: PROCEDURE: Intraarterial bone marrow progenitor cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Lidocaine|DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis
Status: WITHDRAWN
Conditions: Cirrhosis|End Stage Liver Disease|Ascites|Hypotension
Interventions: DRUG: Midodrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress
Status: RECRUITING
Conditions: Post-traumatic Stress
Interventions: DEVICE: Cervical Transcutaneous Vagus Nerve Stimulation (Active Comparator)|DEVICE: Cervical Transcutaneous Vagus Nerve Stimulation (Sham Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extracorporeal Shockwave Myocardial Revascularization (ESMR) Therapy For The Treatment of Chronic Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Cardiospec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupoint Stimulation Improves Fatigue and Sleep Quality in Patients With Postdialysis
Status: COMPLETED
Conditions: Hemodialysis
Interventions: DEVICE: Acupoint stimulation|DEVICE: Acupoint stimulation(placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Three Transfusion Strategies for Central Venous Catheterization in Cirrhotics: A Randomized Clinical Trial
Status: TERMINATED
Conditions: Liver Cirrhosis
Interventions: OTHER: Coagulogram-based protocol|OTHER: Thromboelastometry-based protocol|OTHER: Restrictive strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunteers
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Nonmalignant Neoplasm|Viral Infection
Interventions: OTHER: cytology specimen collection procedure|OTHER: fluorescent antibody technique|PROCEDURE: assessment of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Commercially Available Vaccines Against SARS-CoV-2 (COVID-19) in Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Monoclonal B-Cell Lymphocytosis|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|B-cell Non Hodgkin Lymphoma|Hodgkin Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: i-CBT Functional Gastrointestinal Disorders in Youth: the Impact of Negative Illness Understanding and Parental Illness Worries
Status: RECRUITING
Conditions: Functional Abdominal Pain Syndrome|Functional Gastrointestinal Disorders|Irritable Bowel Syndrome
Interventions: OTHER: Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of CM338 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: CM338|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracardiac Versus Transesophageal Echocardiography Versus Fluoroscopy Only Guidance for Combined Catheter Ablation for Atrial Fibrillation and Left Atrial Appendage Occlusion
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: LAAC combined with radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Citalopram Titration in Early Non-responder Patients With Major Depressive Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Citalopram 20mg or 40 mg (phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening
Status: TERMINATED
Conditions: Infertility|Preimplantation Genetic Screening
Interventions: DIAGNOSTIC_TEST: Preimplantation Genetic Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation Cycling in SCI
Status: UNKNOWN
Conditions: Spinal Cord Injury, Acute|Paraplegia|Tetraplegia
Interventions: DEVICE: FES Cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Using IMC-A12 (Cixutumumab) With or Without Cetuximab in Participants With Metastatic Colorectal Cancer Who Have Failed a Treatment Regimen That Consisted of a Prior Anti-EGFR Therapy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: IMC-A12|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Hormonal Therapy Combined With Central Memory T Cells (Tcm) for Patients With Advanced Prostate Cancer
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: Tcm+ Goserelin acetate+ Bicalutamide|BIOLOGICAL: Tcm+Goserelin acetate+Abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effects of Brimonidine Intravitreal Implant in Patients With Glaucomatous Optic Neuropathy
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: 400 ug Brimonidine Implant|DRUG: 200 ug Brimonidine Implant|DRUG: Sham (no implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Discharge Transitional CGM Study (DDT-CGM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: CGM device with diabetic education, CGM education and a follow up protocol.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Merlin's DiVeRt - Vascular Reconstruction Device and Delivery System
Status: UNKNOWN
Conditions: Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm, Lesion
Interventions: DEVICE: DiVeRt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
Status: RECRUITING
Conditions: Drug Resistant Epilepsy|Medically Refractory Epilepsy|Refractory Epilepsy
Interventions: DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-angiogenesis Combine With EGFR-TKI in Advanced Non-squamous Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: EGFR-TK Inhibitor|DRUG: Anti-Angiogenic Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY 43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006) + carboplatin + paclitaxel|DRUG: Carboplatin plus Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: All-ceramic Crowns in Patients With Sleep Bruxism
Status: COMPLETED
Conditions: Sleep Bruxism|Monolithic Ceramic Fixed Dental Prosthesis (Single Crowns)
Interventions: DEVICE: Zirconia crowns (Prettau®)|DEVICE: lithium disilicate crowns (IPSe.max®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Art Therapy and Music Reminiscence Activity in the Prevention of Cognitive Decline
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Art Therapy|BEHAVIORAL: Music Reminiscence Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotic Supplementation During Pregnancy in Preeclampsia High-risk Groups
Status: NOT_YET_RECRUITING
Conditions: PE (Pre-eclampsia) High-risk Population With Gut Microbiota Dysbiosis During Their Pregnancy
Interventions: DIETARY_SUPPLEMENT: aspirin 100mg and probiotics 1 bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quality of Life for Carers Through a Person-Centred Technological Solution
Status: RECRUITING
Conditions: Informal Caregivers|Quality of Life|Technology|Activities of Daily Living
Interventions: DEVICE: TechQoL4Carers Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does a Nitrofurazone Coated Bladder Catheter Reduce the Number of Urinary Tract Infections in Trauma
Status: UNKNOWN
Conditions: Trauma|Urinary Tract Infections
Interventions: DEVICE: Nitrofuranzone coated bladder catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases
Status: COMPLETED
Conditions: Breakthrough Bleeding
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Skin-to-Skin Care Helpful for Preterm Infants and Their Mothers After Birth?
Status: COMPLETED
Conditions: Moderate to Late Prematurity
Interventions: BEHAVIORAL: Skin-to-Skin contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Prucalopride in Subjects With Moderate and Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: prucalopride|DRUG: prucalopride|DRUG: prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Status: UNKNOWN
Conditions: to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Interventions: DEVICE: Negative Pressure Wound Therapy|OTHER: Standard Gauze Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dental Fluorosis Risk by the Use of Acidulated Fluoride Dentifrice
Status: COMPLETED
Conditions: Caries, Dental|Fluorosis, Dental
Interventions: OTHER: Use of Dentifrice Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Budd-Chiari Syndrome in China: Balloon Angioplasty Alone or Combined With Stent Placement?
Status: COMPLETED
Conditions: Budd-Chiari Syndrome
Interventions: DEVICE: Stent|DEVICE: Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: mezigdomide|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inmobilization With Compression Bandage vs Antebraquial Splint in Distal Radius Fractures
Status: RECRUITING
Conditions: Distal Radius Fractures|Internal Fixation; Complications, Mechanical
Interventions: DEVICE: Splint inmmobilization|DEVICE: Bandage immovilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Betahistine Dihydrochloride in the Treatment of Major Depression With Atypical Features
Status: TERMINATED
Conditions: Recurrent Major Depressive Disorder With Atypical Features
Interventions: DRUG: betahistine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: REACH robotic training and multi-muscle Functional Electrical Stimulation (FES) group|COMBINATION_PRODUCT: Robot only group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Hormone-sensitive Prostate Cancer
Interventions: DRUG: androgen-deprivation therapy|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Merkel Cell Carcinoma|Advanced or Metastatic Cutaneous Squamous Cell Carcinoma|Advanced or Metastatic Melanoma|Advanced or Metastatic Head and Neck Squamous Cell Carcinoma|Advanced or Metastatic Solid Tumors
Interventions: DRUG: Cavrotolimod|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Cemiplimab|DRUG: Cavrotolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IOPS Technology During Cannnulation of Contralateral Limb in EVAR
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm|Abdominal Aortic Aneurysm Without Rupture|Radiation Exposure
Interventions: DEVICE: Intra-Operative Positioning System (IOPS)|DEVICE: Conventional group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Posaconazole in Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|CARD9 S12N Risk Allele
Interventions: DRUG: Posaconazole Delayed Release Oral Tablet|DRUG: Matching Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT