pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Clino-san on Vaginal Dryness of Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Vaginal Atrophy
Interventions: DRUG: clino-san vaginal lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Drug-drug Interactions (DDIs) Between SKLB1028 and Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: SKLB1028|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Abdomen and Delayed Anastomosis After Anastomotic Dehiscences to Avoid Stomas
Status: UNKNOWN
Conditions: Anastomotic Complication|Anastomotic Leak Small Intestine|Anastomotic Leak Large Intestine
Interventions: PROCEDURE: Damage Control Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Activated Prothrombin Complex for Prevention of Bleeds in Hemophilia A With Inhibitors
Status: COMPLETED
Conditions: Hemophilia A With Inhibitors
Interventions: DRUG: activated prothrombin complex concentrate (FEIBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia.
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Lymphocytic Leukemia
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy
Status: RECRUITING
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ultra-narrow Diameter Implants (2,75 mm) Without Bone Regeneration Versus Standard Diameter Implants (4,3 mm) in Combination With Bone Regeneration
Status: UNKNOWN
Conditions: Dental Implant|Narrow Implant|Implant Fracture|Guided Bone Regeneration
Interventions: PROCEDURE: Standard implant|PROCEDURE: Ultra-narrow implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study to Evaluate the Effects of Experimental Medication BMS-986256 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986256|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirabegron and Oxybutynin Safety and Efficacy Trial in Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Urinary Bladder, Neurogenic
Interventions: DRUG: Oxybutynin Chloride IR|DRUG: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Tobradex AF
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Tobramycin 0.3% / Dexamethasone 0.033% ophthalmic suspension|DRUG: Tobramycin 0.3% / Dexamethasone 0.1% ophthalmic suspension (TOBRADEX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Factor (SCF) Priming of Haematopoietic Stem Cell Grafts in Malignant Lymphoma
Status: TERMINATED
Conditions: Malignant Lymphoma
Interventions: DRUG: r-metHuSCF and Filgrastim|DRUG: r-metHuSCF and Filgrastim|DRUG: Chemotherapy plus Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-TURBT TC-3 Gel Intravesical Instillation in NMIBC
Status: COMPLETED
Conditions: Carcinoma of Urinary Bladder, Superficial
Interventions: DEVICE: 40 mg MMC gel|OTHER: Standard of care MMC mixed with water|DEVICE: 80 mg MMC gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barbed Sutures Versus Conventional Sutures in Laparoscopic Excision of Endometrioma
Status: UNKNOWN
Conditions: Endometriosis
Interventions: PROCEDURE: Cystectomy using barbed sutures|PROCEDURE: Cystectomy using conventional sutures|DEVICE: V-Loc (Covidien, Mansfield, MA)|DEVICE: polyglactin 910 suture(VICRYL™, Ethicon Inc, Sommerville, NJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Hydromorphone HCL 16mg; Dilaudid SR 16mg; Naltrexone (opioid antagonist) 50mg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Postoperative Pain|Postoperative Cognitive Dysfunction|Total Knee Arthroplasty
Interventions: DRUG: Normal saline|DRUG: Esketamine at high dose|DRUG: Esketamine at low dose|DRUG: Ketorolac at high dose|DRUG: Ketorolac at low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 4
Status: UNKNOWN
Conditions: Trapeziometacarpal Osteoarthritis|Thumb Carpometacarpal Osteoarthritis
Interventions: PROCEDURE: Trapeziectomy with LRTI|PROCEDURE: Trapeziectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK112 Monotherapy in Advanced/Metastatic Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: AK112 monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Management In Patients Undergoing Hullax Valgus Surgery
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: IV fentanyl PCA|PROCEDURE: local bupivacaine infiltration and post-OP IV fentanyl PCA|PROCEDURE: Nerve Blocks and post-OP IV fentanyl PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SPG302 in Healthy Volunteers and ALS Participants
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: SPG302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China
Status: RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|HPV Infection|Virus Integration|HSIL, High Grade Squamous Intraepithelial Lesions
Interventions: OTHER: Follow up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dentists' Understanding of Diagnostic Test Results and Treatment Efficacy.
Status: COMPLETED
Conditions: Health Education
Interventions: OTHER: Dental health information form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Participants With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Enzastaurin|DRUG: Sunitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Ventilation in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: BILEVEL (Respironics)|DEVICE: Continuos positive airway pressure (Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Putative Cognitive Enhancer VU319
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: Single Dose of VU319|DRUG: Single Dose Placebo|OTHER: Fed State|OTHER: Fasted State|DRUG: Dose Escalation of VU319|DRUG: Placebo Dose Escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Duloxetine|DRUG: Escitalopram|DRUG: BMS-820836 Placebo|DRUG: BMS-820836|DRUG: BMS-820836|DRUG: BMS-820836|DRUG: BMS-820836
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Parenteral L-carnitine Supplementation in Premature Neonates
Status: COMPLETED
Conditions: Complication of Prematurity
Interventions: DRUG: Parenteral L-carnitine supplementation|DRUG: Parenteral supplementation with sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Intravenous Peramivir in Subjects With Uncomplicated Influenza.
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Peramivir|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Biphasic Insulin Aspart 30 in Type 2 Diabetics Failing on OADs
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib With Pemetrexed to Treat Relapsed/Refractory Primary and Secondary Central Nervous System (CNS) Lymphomas
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma|Secondary Central Nervous System Lymphoma|Relapsed Cancer|Refractory Cancer
Interventions: DRUG: Pemetrexed|DRUG: Zanubrutinib|PROCEDURE: Autologous Stem Cell Transplant (ASCT)|RADIATION: Whole Brain Radiation Therapy (WBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Unbundling of cords|OTHER: Bundling of cords
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Bioavailability Study of Colcrys® in Apple Juice
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: colchicine 0.6 mg tablet|DRUG: colchicine 0.6 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects
Status: COMPLETED
Conditions: Hepatic Impairment|NASH - Nonalcoholic Steatohepatitis|Cirrhosis, Liver
Interventions: DRUG: MGL-3196
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Lorcaserin for Cocaine Use: The TLC Study
Status: TERMINATED
Conditions: Cocaine Use Disorder
Interventions: DRUG: lorcaserin|DRUG: Placebo Oral Tablet|BEHAVIORAL: Substance use counseling|BEHAVIORAL: ACASI|DIAGNOSTIC_TEST: Cocaine metabolites|BEHAVIORAL: Ecological Momentary Assessment (EMA)|BEHAVIORAL: Balloon Analogue Risk Task (BART)|BEHAVIORAL: Qualitative Exit Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy
Status: RECRUITING
Conditions: Uncontrolled Asthma
Interventions: DRUG: Experimental: CHF6001 3200 μg|DRUG: Placebo Comparator: CHF6001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Early Stage Bulky Cervical Cancers
Status: UNKNOWN
Conditions: Carcinoma Cervix
Interventions: DRUG: Chemotherapy|RADIATION: External Beam Radiotherapy|RADIATION: Brachytherapy|PROCEDURE: Radical Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Electroacupuncture for Functional Dyspepsia Based on "Enterotypes" and Metabolomics
Status: NOT_YET_RECRUITING
Conditions: Functional Dyspepsia
Interventions: OTHER: Electro-acupuncture|OTHER: Sham electro-acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix Porcine Circovirus (PCV)-Free Liquid Compared to Rotarix Liquid Given in 2-doses in Healthy Chinese Infants Starting at Age 6-16 Weeks
Status: RECRUITING
Conditions: Gastroenteritis
Interventions: COMBINATION_PRODUCT: GSK's liquid oral live attenuated HRV|COMBINATION_PRODUCT: PCV-free liquid formulation of GSK's oral live attenuated HRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: What Factors Are Associated With Prognosis of Rotator Cuff Disorder After Subacromial Hyaluronic Acid Injection
Status: UNKNOWN
Conditions: Rotator Cuff Impingement Syndrome
Interventions: DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effects of Electroacupuncture on Balance in Subjects With Chronic Functional Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DEVICE: Asia-Med Special No 16 (0.30x30mm) needles|DEVICE: Streitberger placebo needles (Asia-Med, 0.03 x 30 mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparing iView Video Laryngoscope in the Emergency Department
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed|Airway Obstruction
Interventions: DEVICE: I View Video Laryngoscope https://www.intersurgical.com/content/files/108253/-1977057700
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Aflibercept in Proliferative Diabetic Retinopathy.
Status: COMPLETED
Conditions: Naive Patients With Uncomplicated Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: panretinal photocoagulation|DRUG: Aflibercept intravitreal injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Ziv Aflibercept in Different Retinal Diseases
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Ziv-Aflibercept 25 MG/ML [Zaltrap]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety Between HCP2001 and Co-administration of Each Component in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP2001|DRUG: RLD2007|DRUG: RLD2008|DRUG: RLD2102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substrate Metabolism, Growth Hormone Signaling, and Insulin Sensitivity During Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Fasting|DRUG: Saline|DRUG: Pegvisomant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
Status: RECRUITING
Conditions: Alzheimer Disease|Alzheimer Disease, Early Onset|Alzheimer Disease, Late Onset|Alzheimer's Disease (Incl Subtypes)|Alzheimer's|Alzheimer's Disease
Interventions: DEVICE: GENUS device (Active Settings)|DEVICE: GENUS device (sham settings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Treating Patients With Early-Stage Rectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: celecoxib|GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|PROCEDURE: biopsy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Liraglutide Adjunct to Insulin Treatment in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: liraglutide|DRUG: liraglutide|DRUG: liraglutide|DRUG: placebo|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care For Me (PCforMe)
Status: COMPLETED
Conditions: Palliative Care
Interventions: BEHAVIORAL: Access to PCforMe for review|BEHAVIORAL: Access to three nationally-recognized Palliative Care websites for review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Following In-House Recombinant Hepatitis B Vaccine in Indonesian Population (Phase III)
Status: NOT_YET_RECRUITING
Conditions: Vaccine Reaction|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Hepatitis B vaccine lot 1|BIOLOGICAL: Hepatitis B vaccine lot 2|BIOLOGICAL: Hepatitis B vaccine lot 3|BIOLOGICAL: Hepatitis B vaccine (registered)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methadone vs Magnesium in Spinal Fusion
Status: COMPLETED
Conditions: Idiopathic Scoliosis
Interventions: DRUG: Methadone hydrochloride|DRUG: Magnesium Sulfate|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The ROle of Compression StocKings in Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure，Congestive|Leg Edema|Venous Insufficiency|Venous Ulcers
Interventions: DEVICE: low grade compression stockings (10-15 mmHg)|DEVICE: high grade compression stockings (20-30 mmHg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anticoagulation in Cirrhotic Patients With Portal Vein Thrombosis：A Multicenter RCT
Status: UNKNOWN
Conditions: Portal Vein Thrombosis|Liver Cirrhosis
Interventions: DRUG: Nadroparin Calcium and Warfarin|DEVICE: Doppler ultrasound and CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BMS-986012 in Subjects With Small Cell Lung Caner
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: BMS-986012|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veterans Inpatient Insulin Study and Transition to Outpatient Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: NPH/Regular 70/30 mix|DRUG: insulin aspart protamine/insulin aspart 70/30 mix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Acute Effects of Electronic Nicotine Delivery Devices Marketed to Smokers.
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: OB|OTHER: Sham smoking|OTHER: CROWN SEVEN|OTHER: NJOY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Omega-3 Polyunsaturated Fatty Acids in Non-surgical Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Therapeutics|Fatty Acids, Unsaturated
Interventions: DIETARY_SUPPLEMENT: fish oil|PROCEDURE: SRP only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimising Neonatal Ventilation With Closed-loop Oxygen Control
Status: RECRUITING
Conditions: Infant, Newborn, Diseases|Mechanical Ventilation Complication
Interventions: DEVICE: Closed-loop automated oxygen control (Oxygenie, SLE6000)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SWIFT - SWIss Factor XIII Trial in PPH
Status: RECRUITING
Conditions: Postpartum Hemorrhage|Coagulation Disorder|Coagulation Factor Deficiency|Hemorrhage|Postpartum Complication
Interventions: DRUG: Fibrogammin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of ASTX727 in Subjects With Lower-risk Myelodysplastic Syndromes
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower-risk Myelodysplastic
Interventions: DRUG: ASTX727|DRUG: ASTX727|DRUG: ASTX727|DRUG: ASTX727|DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occurrence of Potential Bacterial and Viral Pathogens in Stable Chronic Obstructive Pulmonary Disease and During Acute Exacerbations of the Disease, in Asia Pacific
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: OTHER: Sputum and blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Game Facilitated Interactivity to Genetic Counseling for Prenatal Screening Education
Status: RECRUITING
Conditions: Genetic Counseling|Shared Decision Making|Pregnancy|Genetic Testing|Prenatal Disorder
Interventions: BEHAVIORAL: Meaning of Screening|BEHAVIORAL: Genetic Counseling|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Beta Glucan Assay in Patients Receiving Voriconazole Prophylaxis
Status: COMPLETED
Conditions: Leukemia|Fungal Infection
Interventions: DRUG: Voriconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intradermal RN1001 (Avotermin) in Elderly Subjects.
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Avotermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Neoplasm Metastasis|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms
Interventions: BIOLOGICAL: Bevacizumab|DRUG: CPT-11|DRUG: 5-FU Bolus|DRUG: 5-FU Infusion|DRUG: l-LV (dl-LV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Polyphenols Combined to L-citrulline on Ambulatory Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: NO Ultra|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Health Effects of Adlay on Hyperlipidemia and Hyperglycemia Control
Status: RECRUITING
Conditions: Hyperlipidemia|Hyperglycemia|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Adlay with white rice|DIETARY_SUPPLEMENT: white rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Malignant Pleural Effusion - Indwelling Pleural Catheter or Talc Pleurodesis
Status: UNKNOWN
Conditions: Pleural Effusion, Malignant|Lung Neoplasms
Interventions: PROCEDURE: Talc Pleurodesis|PROCEDURE: Indwelling Pleural Catheter|PROCEDURE: chest ultrasound|DRUG: Local anesthesia|PROCEDURE: Chest Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biochemical Role of Long Non-coding RNA MALAT 1 and Serum Tumor Necrosis Factor Alpha in Bronchial Asthma Patients.
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DIAGNOSTIC_TEST: Long non-coding MALAT1 gene expression assay:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EXOPULSE Mollii Suit, Spasticity, Muscular Oxygenation & Multiple Sclerosis (ENNOX 2)
Status: RECRUITING
Conditions: Sclerosis, Multiple|MS (Multiple Sclerosis)|Spastic|Spasticity, Muscle|Oxygen Consumption
Interventions: DEVICE: EXOPULSE Mollii Suit Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilocarpine Microneedles for Sweat Induction (PMN-SI)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Pilocarpine microneedle patch|DEVICE: Pilocarpine Iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Energy Balancing Modeling and Mobile Technology to Support e-Weight Loss
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Online Behavioral Weight Loss program|BEHAVIORAL: Weight Loss Nomogram|BEHAVIORAL: Bite Counter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: TOL2506|DRUG: Tamoxifen|DRUG: Letrozole Tablets|DRUG: Anastrozole Tablets|DRUG: Exemestane Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine Treatment Satisfaction With Treximet Versus Concomitant 2 Aleve and Imitrex
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Treximet|DRUG: Imitrex and two Aleve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteoclast Inhibition and Bone Formation
Status: COMPLETED
Conditions: Bone Loss|Aging
Interventions: DRUG: placebo|DRUG: denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: 5-Methoxypsoralen|DEVICE: UVA1 phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Genexol-PM and Gemcitabine in Patients With Advanced Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Genexol-PM/Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Jiajian Guishen Granules on the Modulation of Ovarian Function in Patients With Poor Ovarian Response(POR)
Status: NOT_YET_RECRUITING
Conditions: Poor Ovarian Response
Interventions: DRUG: Jiajian Guishen granules|DRUG: coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Carboplatin in Triple Negative Breast Cancer
Status: COMPLETED
Conditions: BRCA1 Hereditary Breast and Ovarian Cancer Syndrome
Interventions: DRUG: Doxorubicin|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Subjects at Risk of Pancreatic Cancer
Status: RECRUITING
Conditions: Familial Pancreatic Cancer|BRCA1 Mutation|BRCA2 Mutation|Lynch Syndrome|FAMMM - Familial Atypical Mole Malignant Melanoma Syndrome|Hereditary Pancreatitis|Peutz-Jeghers Syndrome
Interventions: RADIATION: MRCP|PROCEDURE: Endoultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Slow Dose Titration Group of Subcutaneous Treprostinil|DRUG: Rapid Dose Titration Group of Subcutaneous Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: THS 2.2 Menthol (mTHS 2.2)|OTHER: Smoking Abstinence (SA)|OTHER: Menthol Conventional Cigarette (mCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mastery Learning Versus Time-based Education: Skill Acquisition and Retention of Basic Life Support in Laypeople
Status: COMPLETED
Conditions: Basic Life Support|Cardiac Arrest
Interventions: OTHER: Mastery based learning|OTHER: Time based learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving Bowel Preparation for the Colon Capsule
Status: COMPLETED
Conditions: Quality of Bowel Preparation for the Colon Capsule|Colon Capsule Completion Rates|Colon Capsule Polyp Detection
Interventions: DRUG: PEG|DRUG: Prucalopride|DRUG: Picosalax|DRUG: Bisacodyl|PROCEDURE: Colon capsule|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Obesity Using Novel Dietary Strategies
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Obesity
Interventions: BEHAVIORAL: Four Diets Differing in Macronutrient Composition|BEHAVIORAL: Diets Low in Saturated Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy and Safety of T2762 Versus Optive® in the Treatment of Moderate to Severe Dry Eye Syndrome
Status: TERMINATED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: T2762|DEVICE: Optive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effect of the Hand Robot on Stroke Patients Upper-lime Rehabilitation of Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: RMTC finger-hand robot (Mirror Hand)|OTHER: Conventional OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Concerning the Frequency of Parastomal Hernia With or Without a Mesh
Status: COMPLETED
Conditions: Parastomal Hernia
Interventions: DEVICE: Polypropylene Mesh, density 25-40g/square meter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of C-peptide on Hypoglycemic Counterregulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoglycemia|Type 1 Diabetes
Interventions: OTHER: Saline|BIOLOGICAL: C-peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Inducible Monomorphic Ventricular Tachycardia (MMVT) in Patients With St. Jude Medical (SJM) Implantable Cardioverter Defibrillator (ICD) Systems or Cardiac Resynchronization Therapy Defibrillation (CRT-D) Systems.
Status: WITHDRAWN
Conditions: Monomorphic Ventricular Tachycardia
Interventions: DEVICE: ICD/CRT-D with NIPS or EP Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
Status: RECRUITING
Conditions: Fistulizing Crohns Disease|Perianal Crohns Disease
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of NBP on the Collateral Circulation in ICA/M1 Occlusion
Status: COMPLETED
Conditions: Cerebrovascular Occlusion|Collateral Blood Circulation|Anterior Cerebral Circulation Infarction
Interventions: DRUG: NBP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Rituximab (RTx) Induction and Living Donation on Immunoregulation and Virus Control in Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Rituximab (RTx)|Living Donors|Immunology|Virus
Interventions: DRUG: Rituximab|PROCEDURE: living donor transplantation|PROCEDURE: deceased donor transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tesmilifene in Combination With Docetaxel in the Treatment of Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Tesmilifene (YMB1002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma
Status: RECRUITING
Conditions: Cutaneous Melanoma|Melanocytic Nevus|Skin Carcinoma
Interventions: OTHER: Confocal Microscopy|OTHER: Dermoscopy|PROCEDURE: Imaging Technique|DRUG: Lidocaine|PROCEDURE: Punch Biopsy|PROCEDURE: Shave Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
Status: COMPLETED
Conditions: Healthcare-associated Pneumonia (HCAP)|Bloodstream Infections (BSI)|Hospital Acquired Pneumonia (HAP)|Complicated Urinary Tract Infection (cUTI)|Sepsis|Ventilator Associated Pneumonia (VAP)
Interventions: DRUG: Cefiderocol|DRUG: Best Available Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Freckles by Intradermal Tranexamic Acid Versus Q Switched KTP Laser.
Status: UNKNOWN
Conditions: Therapeutic Efficacy
Interventions: DRUG: Tranexamic Acid Injectable Product|DEVICE: Q switched KTP (532nm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Status: ENROLLING_BY_INVITATION
Conditions: Tuberculosis|Gastric Cancer|Peptic Ulcer|Atrophic Gastritis|Intestinal Metaplasia|Gastric Dysplasia|Colorectal Cancer|Colorectal Polyp|Colorectal Adenoma|Pancreatic Cancer|Pancreatitis, Chronic|Liver Cancer|Liver Cirrhosis|Flu, Human|Other Infectious Diseases|Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: VOC detection in breath and in skin headspace|DIAGNOSTIC_TEST: Breath sampling|PROCEDURE: Upper endoscopy with biopsies|PROCEDURE: Colonoscopy with biopsies|PROCEDURE: Whole blood/ Plasma / serum sampling|DIAGNOSTIC_TEST: Faecal sampling|PROCEDURE: Histological examination of surgical specimen|DIAGNOSTIC_TEST: Headspace analysis for biological material
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Easing Psychosocial Burden for Informal Caregivers
Status: COMPLETED
Conditions: Glioblastoma
Interventions: BEHAVIORAL: Focus Group|BEHAVIORAL: Meaning-Centered Psychotherapy for Cancer Caregivers / MCP-C|BEHAVIORAL: Enhanced Usual Care / EUC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on the Possible Health Effects of Lean Fish and Fatty Fish Intake in Overweight or Obese Adults
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: OTHER: Lean fish|OTHER: Fatty fish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-escalated Treatment Approach for Adult Ph-negative Acute Lymphoblastic Leukemia (ALL)
Status: UNKNOWN
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: PROCEDURE: Autologous HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Determinants Affecting Fluoro-L-thymidine (FLT) Positron Emission Tomography (PET) in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DEVICE: PET imaging with [18F]-FLT|DRUG: [18F]-fluorodeoxythymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Crossover Study of DWJ1525 to Evaluate the Safety and Pharmacokinetic Properties in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWJ1525|DRUG: DWP16001|DRUG: DWC202101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation
Status: ACTIVE_NOT_RECRUITING
Conditions: no Condition|Electroencephalography|Pupil Diameter
Interventions: DEVICE: Transdermal Vagus Nerve Stimulation (tVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Research Study of CP-724,714 in Patients With HER2 Overexpressing Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: CP-724,714
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Male Subjects to Demonstrate Bioequivalence of 1600 μg Selexipag Administered as Eight Tablets of 200 μg or as Single Tablet of 1600 μg
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: selexipag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Bleed Free Treatment of Menopausal Symptoms With New Ultra Low Dose Hormonal Combinations
Status: COMPLETED
Conditions: Menopause|Menopausal Vasomotor Symptoms
Interventions: DRUG: 0.5 mg estradiol / 0.1 mg norethisterone acetate (NETA)|DRUG: 0.5 mg estradiol / 0.25 mg norethisterone acetate (NETA)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Self-administered Auricular Acupressure on Insomnia Induced by Anxiety
Status: UNKNOWN
Conditions: Insomnia Due to Anxiety and Fear
Interventions: OTHER: Vaccaria seed (Wang Bu Liu Xing) pre-attached to adhesive tape used for auricular acupressure|OTHER: Plain ear adhesive tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Therapy for Choroidal Neovascularization (CNV) Asociated With Angioid Streaks
Status: WITHDRAWN
Conditions: Angioid Streaks
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detemir: Role in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin Detemir mixed with RAI injection|DRUG: Insulin Detemir and RAI injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HF158K1 in Participants With HER-2 Positive or HER-2 Low Expression Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors, Adult
Interventions: DRUG: HF158K1 /Arm 2 mg/m²|DRUG: HF158K1 /Arm 6 mg/m²|DRUG: HF158K1 /Arm 15 mg/m²|DRUG: HF158K1 /Arm 30 mg/m²|DRUG: HF158K1 /Arm 45 mg/m²|DRUG: HF158K1 /Arm 60 mg/m²
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab Combined With Chemotherapy as Neoadjuvant Therapy in Adcanced Esophageal Squamous Cell Carcinoma (ESCC)
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab, Albumin Paclitaxel, Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Peritoneal Fixation on Lymphocele Formation
Status: COMPLETED
Conditions: Prostate Cancer|Lymphocele After Surgical Procedure
Interventions: PROCEDURE: Peritoneal fixation (PerFix)|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Plus Bevacizumab in Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: SVG101 (T)|DRUG: Afinitor (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Study in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: ER tablet 25 mg AZD3241|DRUG: ER tablet 100 mg AZD3241|DRUG: Placebo for AZD3241 25 mg|DRUG: Placebo for AZD3241 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug Impregnated Bioabsorbable Stent in Asian Population Extremity Arterial Revascularization (DISAPEAR Study)
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: BVS, Abbott Vascular
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lifestyle Intervention to Reduce the Risk of Sarcopenia in Adults With Diabetes & Obesity Treated With Semaglutide
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus in Obese
Interventions: BEHAVIORAL: Wegovy (2.4 Mg Dose) + exercise & nutrition|OTHER: Wegovy (2.4 Mg Dose) + usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT