pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Brief Affirmation Intervention on HIV-related Distress and Positive Living in Lesotho
Status: COMPLETED
Conditions: Self-affirmation Plus Positive Living Counseling|Counseling
Interventions: BEHAVIORAL: Self-affirmation|BEHAVIORAL: Positive living counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: VIRtual Versus UsuAL In-office Care for Multiple Sclerosis (VIRTUAL-MS)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Multiple Sclerosis Clinical Care Delivery via telehealth|OTHER: Multiple Sclerosis Clinical Care Delivery via standard in clinic visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 177Lu-PSMA-I＆T PSMA Radioligand Therapy in Metastatic Castration-Resistant Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 177 Lu-PSMA-I&T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Treatment for Decompensated Liver Cirrhosis
Status: UNKNOWN
Conditions: Decompensated Liver Cirrhosis
Interventions: BIOLOGICAL: umbilical cord-derived mesenchymal stem cell|OTHER: Comprehensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cincalcet and Vascular Arterial Stiffness Among Peritoneal Dialysis Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Hyperparathyroidism|Arterial Stiffness
Interventions: DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of NVP-2203 Tablet in Patients
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: NVP-2203|DRUG: NVP-2203-R1|DRUG: NVP-2203-R2|DRUG: NVP-2203-R3|DRUG: NVP-2203 Placebo|DRUG: NVP-2203-R1 Placebo|DRUG: NVP-2203-R2 Placebo|DRUG: NVP-2203-R3 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
Status: COMPLETED
Conditions: Signs of Facial Aging With Volume Loss in the Upper Cheeks, Nasolabial Folds and Marionette Lines
Interventions: DEVICE: RADIESSE® (+) Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Atorvastatin 10 mg Versus 40 mg in Eight Months Follow-up Coronary Flow Reserve and Bone Marrow Stem Cell Mobilization in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy in SBRT of HCC ≤5 cm With or Without TACE
Status: RECRUITING
Conditions: Small Hepatocellular Carcinoma|Stereotactic Body Radiation Therapy|Transcatheter Arterial Chemoembolization
Interventions: PROCEDURE: transcatheter arterial chemoembolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Risk Stratification Directed Conditioning Regimen for Haploidentical HSCT in SAA
Status: UNKNOWN
Conditions: Aplastic Anemia|Stem Cell Transplant Complications|Engraft Failure
Interventions: DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy
Status: WITHDRAWN
Conditions: Radical Prostatectomies
Interventions: DRUG: Tramadol|DRUG: Gabapentin|DRUG: Hydrocodone-Acetaminophen|DRUG: Oxycodone-Acetaminophen|DRUG: Ketorolac|DRUG: Acetaminophen|DRUG: Ketorolac tromethamine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections
Status: TERMINATED
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection|Bloodstream Infection|Severe Infection|Pseudomonas Aeruginosa|Acinetobacter Infections|Gram-Negative Bacterial Infections|Human|Carbapenem Resistant Bacterial Infection|Bacteremia|Sepsis
Interventions: OTHER: Duration of therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of TVSG and HS in Determining Endometrial Pathologies
Status: COMPLETED
Conditions: Abnormal Uterine Bleeding
Interventions: DEVICE: Transvaginal ultrasound|DEVICE: Hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: To Assess the Efficacy and Safety of the Cardio Formulation in Reducing Oxidized LDL
Status: TERMINATED
Conditions: Oxidized Low Density Lipoprotein
Interventions: DIETARY_SUPPLEMENT: Cardio formulation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Re-treatment of HCV Following DAA Failure
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Sof+Ledi+R arm|DRUG: Sof+Ledi+R+Peg-IFN arm|DRUG: Sof+Dacla+R arm|DRUG: Sof+Dacla+R+Peg-IFN arm|DRUG: Sof+Velpa+R arm|DRUG: Sof+Velpa+R+Peg-IFN arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Outcomes for Young Autistic Children
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Social Communication|BEHAVIORAL: Disruptive Behavior|BEHAVIORAL: Social Communication + Reduce Frequency|BEHAVIORAL: Social Communication + Add Tools|BEHAVIORAL: Disruptive Behavior + Reduce Frequency|BEHAVIORAL: Disruptive Behavior + Add Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With Heparin Sodium in Intravenous Administration
Status: SUSPENDED
Conditions: Heparin
Interventions: BIOLOGICAL: Sodium heparin UQ Intravenous drug administration|BIOLOGICAL: Sodium heparin FK Intravenous drug administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure
Status: COMPLETED
Conditions: Non-Ischemic Heart Failure
Interventions: DRUG: Allogeneic Mesenchymal Bone Marrow Cells (aMBMC)|DRUG: Lactated Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interest of Levosimendan Preconditioning for Cardiac Surgery Under CEC in Heart Failure Patients With Impaired Ejection Fraction
Status: RECRUITING
Conditions: Levosimendan|Cardiac Surgery|Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Levosimendan|DRUG: No Levosimendan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Sensitive Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Abiraterone Acetate|DRUG: Antiandrogen Therapy|DRUG: Apalutamide|DRUG: Prednisone|PROCEDURE: Computed Tomography|PROCEDURE: Bone Scan|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: allogeneic, donor-derived NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vitamin D and Statins to Treat Hypercholesterolemia
Status: UNKNOWN
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: vitamin D3 tablets|DRUG: placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Varenicline for the Treatment of Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Residential Ventilation Systems and Filtration for Asthma Control in Adults
Status: COMPLETED
Conditions: Asthma|Pollution; Exposure
Interventions: DEVICE: Residential mechanical ventilation system (Exhaust)|DEVICE: Residential mechanical ventilation system (CFIS) and air filtration upgrades|DEVICE: Residential mechanical ventilation system (ERV) and air filtration upgrades
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Versus Standard Paravertebral Blockade in Breast Surgery
Status: UNKNOWN
Conditions: Regional Anaesthesia|Mastectomy|Breast-Conserving Surgery
Interventions: PROCEDURE: Ultrasound guided paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Internet-Based Education Program for Care Partners of People Living With Dementia
Status: COMPLETED
Conditions: Dementia|Burden, Caregiver|Self Efficacy|Knowledge
Interventions: OTHER: Education Intervention|OTHER: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Novel ERG for Detection of Hydroxychloroquine Retinopathy
Status: RECRUITING
Conditions: Hydroxychloroquine Retinopathy
Interventions: DIAGNOSTIC_TEST: Hand-Held Full-Field Skin-Electrode Electroretinography (Device to be evaluated)|DIAGNOSTIC_TEST: Trolley-Mounted Multifocal Skin-Electrode Electroretinography (Device to be evaluated)|DIAGNOSTIC_TEST: Spectral-Domain Optical Coherence Tomography (Standard of Care test)|DIAGNOSTIC_TEST: Macular Autofluorescence (Standard of Care test)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Indapamide SR 1.5 mg With HCTZ 25 mg, in Combination With an ACE-inhibitor, in Patients With Mild to Moderate AHT and Type 2 DM
Status: COMPLETED
Conditions: Hypertension|Type 2 Diabetes Mellitus
Interventions: DRUG: Hydrochlorothiazide|DRUG: Indapamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose
Status: COMPLETED
Conditions: Bowel Preparation for Colonoscopy
Interventions: DRUG: Polyethylene Glycol-Based Lavage|DRUG: Pico-Salax (Magnesium Citrate) plus Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Parkinson's Disease Inpatient Clinical Knowledge and Management
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DEVICE: Watch Rx system|OTHER: Parkinson's Disease Inpatient Clinical Knowledge and Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem
Status: NOT_YET_RECRUITING
Conditions: Shoulder Arthritis|Shoulder Osteoarthritis|Arthrosis|Osteoarthritis|Rheumatoid Arthritis|Arthroplasty|Avascular Necrosis|Humeral Fractures|Cuff Tear Arthropathy
Interventions: DEVICE: SMR TT Hybrid Glenoid without Cementless Finned Short Stem|DEVICE: SMR TT Hybrid Glenoid with Cementless Finned Short Stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nasogastric Tube Placement on Intubated Patient: Two-Finger Method vs Reverse Sellick's Maneuver
Status: COMPLETED
Conditions: Adult Patient Undergoing Elective Surgery With General Anesthesia and Needs Nasogastric Tube Placement
Interventions: PROCEDURE: two-finger method, reverse sellick's method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the Treatment of Arsenical Palmar Keratosis
Status: COMPLETED
Conditions: Chronic Arsenic Poisoning
Interventions: DRUG: Neem plus propylene glycol plus salicylic acid|DRUG: Salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH
Status: RECRUITING
Conditions: Pulmonary Vascular Disorder|Primary Pulmonary Hypertension|Systemic Sclerosis|Other Systemic Involvement of Connective Tissue
Interventions: DRUG: Riociguat Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FAB Block vs. Placebo for Hip Arthroplasty Patients
Status: NOT_YET_RECRUITING
Conditions: Hip Arthroplasty|Anesthesia, Regional|Femoral Articular Branch Block
Interventions: PROCEDURE: Femoral Articular Branch Block|PROCEDURE: Placebo Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attenuation of Corticosteroid Induced Hippocampal Changes
Status: COMPLETED
Conditions: Organic Memory Impairment
Interventions: DRUG: Memantine 10 mg capsule|DRUG: Memantine-matched Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of an Animated Video on Preoperative Anxiety in Children Undergoing Elective Otoplasty
Status: RECRUITING
Conditions: Pre-operative Anxiety|Otoplasty|Paediatric Surgery
Interventions: OTHER: animated video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health
Status: RECRUITING
Conditions: Cognitive Performance|Memory|Mood|Anxiety
Interventions: OTHER: Muscadine Wine Polyphenol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-term Safety Study of Fixed Dose Combination Therapy Fluticasone Furoate/Umeclidinium Bromide/Vilanterol Trifenatate in Japanese Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF/UMEC/VI 100/62.5/25 mcg|DRUG: FF/UMEC/VI 200/62.5/25 mcg|DRUG: Salbutamol|OTHER: ACQ-7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of SCH 486757 in Subjects With Chronic Cough (Study P04887)
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: SCH 486757|DRUG: Placebo Dose 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Prediabetes Remission in Adults With Coronary Heart Disease
Status: COMPLETED
Conditions: Prediabetic State|Coronary Heart Disease|Healthy Lifestyle|Remission
Interventions: BEHAVIORAL: Lifestyle changes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LFX453
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LFX453 H1|DRUG: LFX453 L1|DRUG: LFX453 H2|DRUG: LFX453 L2|DRUG: Imiquimod|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TechSAge Tele Tai Chi for People Aging With Mobility Disabilities
Status: COMPLETED
Conditions: Aging|Disability Physical
Interventions: BEHAVIORAL: Tele Tai Chi Intervention for Persons Aging with Long-Term Mobility Disabilities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sildenafil Exercise: Role of PDE5 Inhibition
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Sildenafil 40mg oral capsule|DRUG: Placebo Oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Laparoscopic Approach in Reducing Postoperative Severe Complications Following Hepatectomy for Colorectal Liver Metastases
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer|Postoperative Complications
Interventions: PROCEDURE: hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Development and Evaluation of Pain Neuroscience Education in Children
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Child, Only
Interventions: OTHER: culture-sensitive PNE4kids|OTHER: standard education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: 2 billion CFU in total of the two strains Lactobacillus paracasei subsp. paracasei and Lactobacillus rhamnosus and arginine.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Early Enteral Dextrose in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: Enteral Dextrose Infusion|OTHER: Free Water Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study On Pazopanib When Given With FOLFOX6 (Fluorouracil, Oxaliplatin, Leucovorin) Or CapeOx (Capecitabine, Oxaliplatin)
Status: COMPLETED
Conditions: Neoplasms, Colorectal
Interventions: DRUG: Pazopanib|DRUG: FOLFOX 6|DRUG: CapeOx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis|Typhoid|Yellow Fever|Rabies|Japanese Encephalitis
Interventions: BIOLOGICAL: Typhoid Vi Polysaccharide Vaccine|BIOLOGICAL: Yellow Fever Vaccine|BIOLOGICAL: Japanese Encephalitis Vaccine|BIOLOGICAL: Rabies Vaccine|BIOLOGICAL: MenACWY-CRM Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Abatacept in earLy Onset Polymyalgia Rheumatica: Study ALORS
Status: UNKNOWN
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Abatacept|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Volume Injection or Autologous Conditioned Plasma (ACP) in Chronic Achilles Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: OTHER: Placebo|DRUG: High Volume injection|BIOLOGICAL: Autologous conditioned plasma (ACP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction
Status: COMPLETED
Conditions: COVID-19 Lower Respiratory Infection|SARS-CoV2 Infection
Interventions: OTHER: Osteopathic Manipulative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Dysfunction in the Addictions Study - Project 4 (P4)
Status: RECRUITING
Conditions: Major Depressive Disorder|Alcohol Use Disorder
Interventions: DEVICE: intermittent theta burst stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation Mobile-Health Fall Risk Prevention Intervention
Status: RECRUITING
Conditions: Cardiac Rehabilitation
Interventions: BEHAVIORAL: Home-based, m-Health Delivered Physical Function Training|BEHAVIORAL: Cardiac Rehabilitation & Exercise Prescription|OTHER: Connected mHealth mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Modafinil|DRUG: Modafinil|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
Status: ENROLLING_BY_INVITATION
Conditions: Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Interventions: COMBINATION_PRODUCT: Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet
Status: COMPLETED
Conditions: Drug-Drug Interaction (DDI)|Healthy Subjects
Interventions: DRUG: EC905|DRUG: verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing Mestinon and Exercise in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Exercise|DRUG: pyridostigmine|DRUG: Placibo|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Liposomal Annamycin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary or Intravenous Infusion Human Wharton' Jelly-derived Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: WJMSCs Vs. placebo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Educator Well-being Program
Status: ENROLLING_BY_INVITATION
Conditions: Participatory Action Research|Occupational Health|Educator Well-being|Employee Health
Interventions: BEHAVIORAL: Healthy Workplace Participatory Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Impact of an Early Biopsy in Patients Treated With CellCept (Mycophenolate Mofetil) After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: mycophenolate mofetil [CellCept]|DRUG: mycophenolate mofetil [CellCept]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: ACC-001 (vanutide cridificar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Immunotherapy|Cutaneous Squamous Cell Carcinoma|Actinic Keratoses|Organ Transplant Recipients|Skin Cancer
Interventions: DRUG: Calcipotriol Only Product in Cutaneous Dose Form|DRUG: Vaseline|DRUG: Topical 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy and Safety of PPC-5650 to Experimental Induced Sensation and Pain in the Rectosigmoid
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PPC-5650|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitric Oxyde Concentration in Chronic Obstructive Pulmonary Disease Patients - SANOB Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Formoterol Fumarate|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparative Trial Focusing on Injections With the Medical Device DV3316 Pen-injector Versus FlexPen®
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: FlexPen®|DEVICE: DV3316 pen-injector|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: R U OK? The Acceptability and Feasibility of New Communication Technologies for Follow-up After Medical Abortion
Status: COMPLETED
Conditions: Legally Induced Abortion, Complete, Without Mention of Complication
Interventions: OTHER: Alternative follow-up protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption
Status: UNKNOWN
Conditions: Gastrointestinal Disease|Flatulence|Gastrointestinal Tolerance|Distension; Bowel|Bloating
Interventions: OTHER: Chilean Native Beans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease
Status: TERMINATED
Conditions: Dry Eye Disease
Interventions: DRUG: P-321 Ophthalmic Solution|DRUG: P-321 Ophthalmic Solution placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm
Status: RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Recurrent Chronic Myelomonocytic Leukemia|Recurrent Myelodysplastic/Myeloproliferative Neoplasm|Refractory Acute Myeloid Leukemia|Refractory Chronic Myelomonocytic Leukemia|Refractory Myelodysplastic/Myeloproliferative Neoplasm
Interventions: DRUG: Azacitidine|DRUG: Gilteritinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 40 Hz Transcranial Stimulation on the Incidence of Delirium After Total Hip Replacement or Total Knee Replacement Arthroplasty in Elderly Patients.
Status: RECRUITING
Conditions: Postoperative Delirium|Anesthesia|Elderly
Interventions: DEVICE: 40Hz stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pazopanib in Combination With Interferon Alfa 2-A, in Patients With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Pazopanib + interferon alpha 2A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Application of Convenient Foot-control Exhaust Method in Endoscopic Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Cancer|Papillary Thyroid Carcinoma|Thyroidectomy|Endoscopy
Interventions: DEVICE: used of the Pressure adjustable foot-control method|DEVICE: direct exhaust
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing TIL to Standard Ipilimumab in Patients With Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: PROCEDURE: Translational research|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2|DRUG: Ipilimumab infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Mobile Technology on Clinical Outcomes in Children and Adolescents With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: text message to parent only|OTHER: text message to parent and adolescent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Improvement in Patients With Parkinson's Disease After Training in Real or Virtual Environment
Status: COMPLETED
Conditions: Parkinson´s Disease
Interventions: DEVICE: Balance Training with Nintendo Wii Fit|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Evaluate the Efficacy of Herbal Ingredients Combined With a Carrier System (Phytonail) Compared With Amorolfine 5% Nail Lacquer (Loceryl) in the Treatment of Toenail Onychomycosis
Status: UNKNOWN
Conditions: Onycomycosis
Interventions: DRUG: Phytonail|DRUG: Loceryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Treatment of Tendinopathy Unruptured of Rotator Cuff by Intramuscular Injection of Botulinum Toxin
Status: UNKNOWN
Conditions: Tendinopathy Rotator Cuff
Interventions: DRUG: Botox arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Node Mapping With Indocyanine Green in Colon Cancer: a Feasibility Trial and a Descriptive Serie.
Status: COMPLETED
Conditions: Colon Cancer|Lymphatic Metastasis
Interventions: PROCEDURE: Sentinel node mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Post-market Clinical Follow-up Study of the HBS 2 Resorb Mg in Patients With Intra- and Extraarticular Fractures, Pseudarthroses and Arthrodesis of Small Bones and Bone Fragments.
Status: RECRUITING
Conditions: Intraarticular Fracture|Extraarticular Fracture|Pseudarthrosis|Arthrosis
Interventions: DEVICE: Treatment with HBS 2 Resorb Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Engagement Strategies to Improve Medication Adherence
Status: TERMINATED
Conditions: Diabetes|Atherosclerosis Cardiovascular Disease|Congestive Heart Failure|Poor Medication Adherence
Interventions: BEHAVIORAL: Social Network Feedback|BEHAVIORAL: Private Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Biphenotypic Acute Leukemia|Undifferentiated Leukemia|Prolymphocytic Leukemia|Myelodysplastic Syndromes|Chronic Myelogenous Leukemia|Myeloproliferative Neoplasm|Relapsed Large Cell Lymphoma|Mantle Cell Lymphoma|Hodgkin Lymphoma|Burkitt Lymphoma|Relapsed T-Cell Lymphoma|Relapsed Chronic Lymphocytic Leukemia|Relapsed Small Lymphocytic Lymphoma|Relapsed Marginal B-cell Lymphoma|Relapsed Follicular Lymphoma|Lymphoplasmacytic Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Melphalan|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stapler vs. LigaSure in Elective Hepatic Resection
Status: COMPLETED
Conditions: Liver Resection
Interventions: PROCEDURE: Stapler hepatectomy|PROCEDURE: LigaSure hepatectomy|DEVICE: Ligasure|OTHER: vascular staple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)|Emphysema|Chronic Bronchitis
Interventions: DRUG: Albuterol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expanded Access Protocol Using 131I-MIBG Therapy +/- Vorinostat for Refractory Neuroblastoma, Pheochromocytoma, or Paraganglioma
Status: NO_LONGER_AVAILABLE
Conditions: Neuroblastoma|Pheochromocytoma|Paraganglioma
Interventions: RADIATION: I-131 MIBG|DRUG: Vorinostat
Study Type: EXPANDED_ACCESS
Clinical trial: Glycemic Control and Variability for Congestive Heart Failure Exacerbation
Status: COMPLETED
Conditions: Congestive Heart Failure|Diabetes Mellitus
Interventions: DRUG: Intravenous insulin|DRUG: Subcutaneous insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Low Intensity Shockwave for the Treatment of Erectile Dysfunction
Status: COMPLETED
Conditions: Vasculogenic Erectile Dysfunction
Interventions: DEVICE: Low Intensity Linear Shockwave Device for the Treatment of Erectile Dysfunction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Mandibular Proximal Segment Position Using Virtual Orthognathic Surgical Planning, Individualized Guides, and Osteosynthesis Plates
Status: RECRUITING
Conditions: CAD-CAM|Patients Specific Manufacturing|Osteotomy, Sagittal Split Ramus
Interventions: DEVICE: conventional splints|DEVICE: cutting guides and positioning guides|DEVICE: cutting guides and fixation plates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect and Safety of Pu Yang Wan Wu Tang and Western Medicine on Chronic Kidney Disease
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Pu Yang Wan Wu Tang plus Pentoxifylline|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Efficacy of a Facial and Lip Moisturizer in Adult Subjects Undergoing a Facial Dermatologic Procedure With Fractional CO2 Laser
Status: COMPLETED
Conditions: Skin Regeneration After Dermatological Facial Procedure With Fractional CO2 Laser
Interventions: OTHER: TH Facial Moisturizer|OTHER: TH Lip Moisturizer|OTHER: Facial Moisturizer B (Control)|OTHER: Sunscreen|OTHER: Facial wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Acute Myeloid Leukemia|Multiple Myeloma|Non-Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: Oral azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracapsular Femoral Neck Fractures Fixation With a Dynamic Locking Plate and Screw System, Targon FN
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: DEVICE: TARGON FN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Awareness-Based Stress Reducatıon Program Applıed to Parents Wıth A Chıld Wıth Autısm
Status: ACTIVE_NOT_RECRUITING
Conditions: DEPRESSION|ANXIETY|STRESS|HOPELESSNESS|MİNDFULNESS
Interventions: OTHER: mindfulness-based stress reduction program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Levulan PDT Versus Vehicle for Extremity Actinic Keratoses (AK)
Status: COMPLETED
Conditions: Keratosis, Actinic
Interventions: DRUG: Aminolevulinic Acid PDT (ALA)|DRUG: Vehicle PDT (VEH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Marker Monitoring (MMM) Study With Gel Matrix Tablets Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Magnetic Marker Monitoring|Gastrointestinal-transport|Gastric Emptying Time|Small Intestinal Transit Time|Time for Colon Arrival|Food Effect
Interventions: DRUG: D1000078|DRUG: D1000082|DRUG: D1000083|DRUG: D1000085
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Clofarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzastaurin For Breast Cancer Patients Who Previously Received an Anthracycline and a Taxane Chemotherapy
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Enzastaurin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of The Use of Baby Mobile Accompanied With Brahms Lullaby On The Infants During Sternum Dressing
Status: COMPLETED
Conditions: Pain, Procedural (During Sternum Dressing on Infants)|Physiological Parameters During Sternum Dressing in Babies
Interventions: BEHAVIORAL: THE USE OF BABY MOBILE ACCOMPANIED WITH BRAHMS LULLABY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Lifitegrast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Shenqu Xiaoshi Oral Liquid on Intestinal Microbiome of Children With Functional Dyspepsia
Status: RECRUITING
Conditions: Dyspepsia|Child
Interventions: DRUG: Shenqu Xiaoshi Oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Chlorhexidine Bathing and Infection Rates in Critically-ill Patients
Status: COMPLETED
Conditions: Healthcare Associated Infections
Interventions: OTHER: Chlorhexidine bathing|OTHER: Non-chlorhexidine bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Step-up Approach vs Aggressive Debridement of Large Pancreatic Walled-off Necrosis
Status: RECRUITING
Conditions: Pancreatic Necrosis|Pancreatitis, Acute Necrotizing
Interventions: PROCEDURE: Direct Endoscopic Necrosectomy|PROCEDURE: Step-up Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Combat Disorders|Ptsd|Nightmare|Nightmares, REM-Sleep Type|Nightmare Disorder With Associated Non-Sleep Disorder
Interventions: DEVICE: NightWare Therapeutic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: HSK21542|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP Adherence Pilot Study Among African Americans
Status: RECRUITING
Conditions: Sleep Apnea
Interventions: BEHAVIORAL: Telemonitoring|BEHAVIORAL: Peer Based|BEHAVIORAL: CPAP Education|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of a Plant-made Seasonal Quadrivalent VLP Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections
Interventions: BIOLOGICAL: Low dose of quadrivalent VLP vaccine|BIOLOGICAL: Medium dose of quadrivalent VLP vaccine|BIOLOGICAL: High dose of quadrivalent VLP vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 First in Human Study of ZN-d5 as a Single Agent
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Non Hodgkin Lymphoma
Interventions: DRUG: ZN-d5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Lymphoma|Toxicity, Cardiac
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy Study in Gastric and Gastroesophageal Junction Cancer Comparing Ipilimumab Versus Standard of Care Immediately Following First Line Chemotherapy
Status: COMPLETED
Conditions: Locally Advanced (Unresectable) or Metastatic Adenocarcinoma of the Gastric and Gastro-esophageal Junction
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Best Supportive care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Inhaled PUR003 on a Controlled Influenza Virus Challenge in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PUR003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS.
Status: COMPLETED
Conditions: Ards|Mechanical Ventilation Pressure High|Extracorporeal Membrane Oxygenation
Interventions: OTHER: No applicable
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p