pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: PA-824
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Trial of Rosuvastatin and Atorvastatin Versus Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: rosuvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial With Vinorelbine and Gemcitabine Versus Docetaxel and Gemcitabine in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel|DRUG: Carboplatin|DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of NBP607-QIV Compared to Agrippal in Children Aged 6 to 35 Months
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: NBP607-QIV|BIOLOGICAL: Agrippal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: Minocycline|DRUG: Placebo|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TmPSMA-02 in mCRPC
Status: RECRUITING
Conditions: Metastatic Castrate-Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: TmPSMA-02 CAR T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Alignment Efficiency of Three Types of Nickel-titanium Archwires
Status: ENROLLING_BY_INVITATION
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: PROCEDURE: orthodontic treatment with fixed appliances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, Panama
Status: WITHDRAWN
Conditions: Tuberculosis|HIV|Histoplasmosis
Interventions: OTHER: Urine LAM Ag test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Cisapride in Patients With Chronic Gastroparesis After Failure of Other Treatment Options
Status: TERMINATED
Conditions: Gastroparesis
Interventions: DRUG: Cisapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging
Status: COMPLETED
Conditions: Patients With Severe Chronic Kidney Disease Being Evaluated With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson
Interventions: DRUG: Aminophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparıson Of Electromyography Results Before And After Vıtamın D Treatment In Patıents Wıth Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Vitamin D Deficiency
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of SCS Technique Verses ART in Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: STRAIN COUNTER STRAIN GROUP|OTHER: ACTIVE RELESAE TECHNIQUE GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy (CEA) (PROTECT)
Status: COMPLETED
Conditions: Carotid Artery Disease
Interventions: DEVICE: Xact Stent with either Emboshield Pro (Gen 5) or Emboshield (Gen 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of TORL-2-307-MAB in Participants With Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor|Gastric Cancer|Pancreas Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: TORL-2-307-MAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity
Status: WITHDRAWN
Conditions: Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: RADIATION: hypofractionated radiation therapy|RADIATION: intensity-modulated radiation therapy|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILD-SARDs Registry and Biorepository
Status: RECRUITING
Conditions: Interstitial Lung Disease|Systemic Autoimmune Disease|Rheumatic Diseases|Rheumatic Arthritis|Systemic Sclerosis|Autoimmune Myositis|Systemic Lupus Erythematosus|Usual Interstitial Pneumonia|Nonspecific Interstitial Pneumonia
Interventions: OTHER: Blood draws|OTHER: Other biological samples to biobank (skin, lung and muscle biopsies; bronchoalveolar lavage (BAL fluid)|OTHER: Clinical data collection|OTHER: Genetic data/DNA/RNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of RO4917838 on the QTcF Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Moxifloxacin|DRUG: Moxifloxacin|DRUG: RO4917838|DRUG: RO4917838|DRUG: RO4917838 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of Preoperative 3D Printing of Distal Intra-articular Radius Fractures on Quality of Fracture Reduction
Status: NOT_YET_RECRUITING
Conditions: Distal Radius Fracture|3D Printing
Interventions: PROCEDURE: Osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensified Short Course Regimen for TBM in Adults
Status: NOT_YET_RECRUITING
Conditions: Tuberculous Meningitis
Interventions: DRUG: High dose rifampicin (25mg/kg)|DRUG: Moxifloxacin 400mg|DRUG: Aspirin 150 mg|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Steroid|DRUG: Rifampicin|DRUG: HRZE|DRUG: HRE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Basal Insulin Therapies for Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin Lispro Protamine Suspension|DRUG: Insulin Levemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients
Status: UNKNOWN
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemo for Non-metastatic Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-squamous Cell Non-Metastatic Non-Small Cell Lung Cancer|Squamous Cell Non-Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Immune Function and MRI Disease Activity in RRMS Patients When Switching From Natalizumab to Gilenya
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Fingolimod|DRUG: Natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, and Pharmacokinetic Study of SC1011 in Healthy Subjects.
Status: COMPLETED
Conditions: Diopathic Pulmonary Fibrosis|Pulmonary Fibrosis
Interventions: DRUG: SC1011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Metformin Extended Release Oral Tablet|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Tapered Applicator for Vaginal Vault Brachytherapy
Status: COMPLETED
Conditions: Endometrial Cancer|Brachytherapy|Quality of Life
Interventions: OTHER: Tapered applicator|OTHER: Standard applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Examine the Effects of a Daily Supplement on Common Symptoms of Perimenopause and Menopause
Status: COMPLETED
Conditions: Menopause|Perimenopause
Interventions: DIETARY_SUPPLEMENT: Daily Balance Gummy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Electroacupuncture on Cognitive Symptoms in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorders|Cognitive Dysfunction
Interventions: PROCEDURE: Electroacupuncture group|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Physical Activity Through a mHealth Intervention in Cardio-metabolic Risk Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Prediabetic State|Hypertension|Prehypertension|Obesity
Interventions: OTHER: FeatForward App (on study smartphone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interest in Combining Intraoperative ElectroEncephaloGram (EEG) With Assessment of Frailty to Predict Postoperative Delirium in Patients Aged >75 Years Undergoing Major Non-cardiac Surgery
Status: RECRUITING
Conditions: Post-operative Delirium
Interventions: BEHAVIORAL: Detection of the Post-operative delirium (POD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Preterm Labor With 17 Alpha-hydroxyprogesterone Caproate
Status: WITHDRAWN
Conditions: Premature Birth|Premature Labor
Interventions: DRUG: 17 hydroxyprogesterone caproate intramuscular injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of Virtual Reality to Reduce Morphine Consumption in Adolescents Undergoing Scoliosis Surgery
Status: RECRUITING
Conditions: Scoliosis
Interventions: DEVICE: Virtual Reality (VR) technique|DRUG: Analgesic protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Village-Integrated Eye Worker Trial II
Status: RECRUITING
Conditions: Age-related Macular Degeneration|Diabetic Retinopathy|Glaucoma
Interventions: OTHER: Visual acuity (presenting and pinhole)|OTHER: Optical coherence tomography (OCT)|OTHER: Intraocular pressure|OTHER: Active linkage to care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Different Premedication in Pediatric Patients
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: dexmedetomidine|DRUG: midazolam|DRUG: midazolam|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Versus Fentanyl Plus Bupivacaine for Epidural Analgesia With General Anesthesia for Lumbar Disc Operations
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Iron Isomaltoside 1000 Administered by 250 mg IV Bolus Injection or 500 mg Intravenous Infusion to Patients With Non-hematological Malignancies Associated With Chemotherapy Induced Anaemia
Status: COMPLETED
Conditions: Patients With Chemotherapy Induced Anemia (CIA)
Interventions: DRUG: Monofer(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multiple-Dose Pharmacokinetics Study of Three Gefapixant (AF-219/MK-7264) Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omeprazole|DRUG: Omeprazole|DRUG: Gefapixant|DRUG: Gefapixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Cochlear Implant MAP-parameters in Children
Status: COMPLETED
Conditions: Cochlear Implants|Evoked Potentials, Auditory|Child|Disabilities Hearing|Deafness|Hearing
Interventions: OTHER: Re-programming of cochlear implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Adding Metformin to Insulin Therapy on Pregnancy Outcomes in Women With Uncontrolled Type I Diabetes.
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men and Women to Find Out How Well Different Doses of BI 1291583 Are Tolerated
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 1291583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Ezetimibe, Simvastatin, and Omega 3- Fatty Acids on Dyslipidemia Patients: a Pharmacokinetics Based Study
Status: UNKNOWN
Conditions: Hyperlipidemia; Mixed
Interventions: DRUG: Ezetimibe 10mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Xerostomia in Burning Mouth Syndrome: Case - Control Study
Status: COMPLETED
Conditions: Burning Mouth Syndrome
Interventions: DRUG: Uréia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Compound Kushen Injection Combined With Pabolizumab in the Treatment of Cervical Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: compound kushen injection combined with pabolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Conditioning Regimen With High-Dose-Etoposide for Allo-HSCT for Adult Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Stem Cell Transplantation, Hematopoietic
Interventions: DRUG: TBI+CY+VP-16|DRUG: FA+TBI+CY+VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHINE Sanitation, Hygiene, Infant Nutrition Efficacy Project
Status: COMPLETED
Conditions: Growth; Stunting, Nutritional|Anemia
Interventions: BEHAVIORAL: Standard care|OTHER: WASH|DIETARY_SUPPLEMENT: Infant and young child feeding|OTHER: WASH and Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China
Status: COMPLETED
Conditions: Anemia|Worm Infections
Interventions: DRUG: ZENTEL|DRUG: ZENTEL and Vitamin A Soft Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study.
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|Major Depressive Disorder
Interventions: OTHER: Acquisition and analysis of relationships between Longitudinal Emotional Signals produced by a software and Self-questionnaires.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Status: TERMINATED
Conditions: Castration-Resistant Prostatic Cancer
Interventions: DRUG: Ipatasertib|DRUG: Atezolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Trial of STING-dependent Activators and Stimulated Dendritic Cells for Aggressive Relapsed/Refractory Leukemias
Status: WITHDRAWN
Conditions: Refractory Leukemia|Relapsed Leukemia|Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Adult T-Cell Leukemia/Lymphoma
Interventions: BIOLOGICAL: STING-Dependent Activators (STAVs) Loaded Autologous Leukemic Cells|BIOLOGICAL: Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immediate Effect of Manual Therapy Application on Respiratory Functions in Healthy Young Individuals
Status: COMPLETED
Conditions: Health Young Individuals
Interventions: OTHER: Manual therapy group|OTHER: Sham-manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Experience and Bowel Preparation for Transvaginal Surgical Management of Vaginal Prolapse
Status: COMPLETED
Conditions: Value of the Bowel Preparation and Diet Change Versus no Intervention|Preoperative Bowel Regimen
Interventions: OTHER: No bowel prep|OTHER: Clear liquid diet and 2 Fleet's enemas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Tilt Angle on Conduction Defects During Transcatheter Aortic Valve Implantation (TAVI)
Status: UNKNOWN
Conditions: TAVI
Interventions: PROCEDURE: transcatheter aortic valve implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of Coronary Calcium With Laser Based Intravascular Lithotripsy for Coronary Artery Disease (FRACTURE)
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Calcification
Interventions: DEVICE: Intravascular lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Management of MRONJ Stages I and II, a Clinical Trial With Detection of Salivary Biomarkers
Status: UNKNOWN
Conditions: Osteonecrosis of the Jaw, Bisphosphonate Induced|Osteonecrosis of the Jaw, Bisphosphonate Related
Interventions: PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: AM001 Cream, 7.5%|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoablation for Post Mastectomy Pain Syndrome
Status: COMPLETED
Conditions: Post-Mastectomy Chronic Pain Syndrome (Disorder)
Interventions: PROCEDURE: Cryoablation|PROCEDURE: Therapeutic Peripheral Nerve Block (tPNB) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of XELOX and EOX in the First-line Treatment of Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Epirubicin|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cycling Off Criteria During Pressure Support Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study for SynGEM, an Intranasal Respiratory Syncytial Virus (RSV) Prefusion F Subunit Candidate Vaccine
Status: UNKNOWN
Conditions: Respiratory Syncytial Viral Infections
Interventions: BIOLOGICAL: SynGEM|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Rehabilitation Programme on Respiratory Function in Patients With Acquired and Intervened Congenital Heart Disease.
Status: NOT_YET_RECRUITING
Conditions: Heart Defects, Congenital
Interventions: OTHER: cardiac rehabilitation program|OTHER: TELEA platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: CS-917|DRUG: metformin hydrochloride|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
Status: TERMINATED
Conditions: Drug-Resistant Epilepsy|Focal-Onset Seizures
Interventions: DRUG: Padsevonil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DuraSeal Sealant Post Market Study
Status: COMPLETED
Conditions: Elective Cranial Procedures With Dural Incision
Interventions: DEVICE: DuraSeal Dural Sealant System|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Smartphone App to Improve Physical Activity
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: OTHER: Physical Activity (PA) Tracker App|OTHER: On Your Feet|OTHER: Coach Me|OTHER: Proof Positive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sintilimab ± IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Sintilimab|DRUG: IBI305|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Placebo1|DRUG: Placebo2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heparin-Free Chronic HemoDialysis Assessment
Status: NOT_YET_RECRUITING
Conditions: End-Stage Renal Disease
Interventions: PROCEDURE: Heparin Anticoagulation|PROCEDURE: Regional Anticoagulation Procedure (RAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Robot-assisted Therapy Combined With Mirror Priming in Upper Limb Training in Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: mirror therapy|DEVICE: robotic-assisted training|DEVICE: sham mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donepezil patch|DRUG: aricept Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Orforglipron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Care Pathway With Electronic Patient Reported Outcomes (ePRO) Post-operative Follow-up of Breast Cancer Surgery Complications to Optimize Patient Quality of Life
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: BEAUTIFY application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CANnabinoids in Pediatric ONCology
Status: NOT_YET_RECRUITING
Conditions: Childhood Cancer|Cancer
Interventions: DRUG: MPL-001|DRUG: MPL-005|DRUG: MPL-009
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Esophageal 3D Mapping System for Cardiac Arrhythmias
Status: COMPLETED
Conditions: Arrhythmia|Atrial Fibrillation|Atrial Flutter|Atrial Tachycardia|Supraventricular Tachycardia|Ventricular Ectopic Beat(S)|Cardiac Arrythmias
Interventions: DEVICE: esoECG-3D catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Plane Block Versus Fentanyl Infusion in Pediatric Patients Undergoing Aortic Coarcitectomy
Status: COMPLETED
Conditions: Aortic Coarctation|Erector Spinae Plane Block|Paediatric
Interventions: DRUG: Fentanyl|PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Protective Role of the L-DOPA Against Age Related Macular Degeneration in Parkinson's Patients
Status: TERMINATED
Conditions: Macular Degeneration, Senile
Interventions: DEVICE: Color retinography|DEVICE: Optical coherence tomography|DEVICE: Fundus autofluorescence imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery
Status: RECRUITING
Conditions: Sore-throat|Nasopharyngeal Pack|Nasal Surgery|Nausea and Vomiting, Postoperative
Interventions: DRUG: Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids
Status: RECRUITING
Conditions: Acute-graft-versus-host Disease
Interventions: DRUG: Ruxolitinib 10 MG Oral Tablet|DRUG: hCG|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Educational Program for Staff in Nursing Homes Concerning Patients Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: BEHAVIORAL: Multifaceted educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Prophylaxis and Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Periodontitis|Gingivitis|Dental Prophylaxis
Interventions: PROCEDURE: Dental Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Obesity
Interventions: BEHAVIORAL: Facility-based Exercise|BEHAVIORAL: Home-based Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Oxford Optimisation of PCI Study (OXOPT-PCI Study)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Optimisation of the result of intracoronary stenting according to specific algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Auryon Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of a Health Coaching Programme for Middle-aged Adults With Cardiometabolic Risk
Status: COMPLETED
Conditions: Cardiometabolic Disease|Health Coaching|Middle-aged Adults|Primary Prevention
Interventions: BEHAVIORAL: Health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Response of Sex Hormones and Different Functions to Exercise and Diet in Elderly Women
Status: COMPLETED
Conditions: Cognitive Decline|Postmenopausal Disorder
Interventions: OTHER: aerobic exercise and MIND diet program|OTHER: MIND diet program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nursing Study of Skin Lesions Related to Health Care Protection in Novel Nursing Study of Skin Lesions Related to Health Care Protection in Novel Coronavirus Epidemic
Status: UNKNOWN
Conditions: Associated Skin Lesions
Interventions: OTHER: Ointment and dressing for external use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Effect of Intravenous Lidocaine on Propofol Requirement in Facial Plastic Surgery
Status: COMPLETED
Conditions: Anesthesia, Intravenous; Surgery, Plastic
Interventions: DRUG: lidocaine|DRUG: normal saline|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)
Status: COMPLETED
Conditions: Epilepsy Intractable
Interventions: DRUG: ABI-009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Needle-free Jet Injection of Insulin on Glucose Control and Injection Feelings in Type 1 Diabetic Patients
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Jet Injector without A Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Interval Training on Pre-Hypertensive Subjects
Status: COMPLETED
Conditions: Metabolism Disorder|Hypertension
Interventions: BEHAVIORAL: High Intensity Interval Training|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pazopanib and Vinflunine in Urothelial Cancer of the Bladder
Status: COMPLETED
Conditions: Advanced Urothelial Cancer of Bladder After Failure of Platinum-containing Therapy.
Interventions: DRUG: Pazopanib as add-on to vinflunine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: MDS
Interventions: DRUG: Darbepoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance
Status: COMPLETED
Conditions: NASH Related Cirrhosis
Interventions: DRUG: Metformin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Eculizumab Therapy to Reduce Preservation Injury in Human Macrosteatotic Liver Transplantation
Status: WITHDRAWN
Conditions: End Stage Liver Disease
Interventions: DRUG: Eculizumab|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asimadoline for the Treatment of Post-Operative Ileus
Status: TERMINATED
Conditions: Post-Operative Ileus
Interventions: DRUG: Asimadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhalations of Ultra-low Doses of Melphalan for the Treatment of Non-cystic Fibrosis Bronchiectasis
Status: UNKNOWN
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: Super-Selective Intraarterial Intracranial Infusion of BEVACIZUMAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Stomach Cancer Induction Chemotherapy and Radiation Therapy
Status: UNKNOWN
Conditions: Locally Advanced Gastric Carcinoma
Interventions: OTHER: Arm 1 pre-operative chemoradiation|OTHER: Arm 2 post operative chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Glasses on Dental Anxiety Control
Status: COMPLETED
Conditions: Periodontitis|Dental Anxiety|Dental Fear|Gingivitis|Calculus, Dental
Interventions: PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery
Status: RECRUITING
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Treatment Effect of Pirfenidone in Chronic Lung Allograft Dysfunction (STOP-CLAD)
Status: TERMINATED
Conditions: Disorder Related to Lung Transplantation|Chronic Lung Allograft Dysfunction
Interventions: DRUG: Pirfenidone Capsule|DRUG: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
Status: UNKNOWN
Conditions: Effect of Superstarch on Soccer Performance
Interventions: DIETARY_SUPPLEMENT: Superstarch|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Assess the Safety and Immunogenicity of the Drug CAT-354 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CAT-354|DRUG: CAT-354|DRUG: CAT 354
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Of Phenytoin Suspension Versus Epamin® In 34 Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epamin: Reference Drug|DRUG: Phenytoin: Study Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Imaging of Pilosebaceous Units and Acne Lesions by RCM and OCT Confocal Microscopy and Optical Coherence Tomography
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: SEB-250
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diastasis Recti Abdominis Association With Sacroiliac Joint and Pelvic Floor Dysfunction in Postpartum C-section Women
Status: COMPLETED
Conditions: Diastasis Recti|Sacroiliac Joint Somatic Dysfunction|Pelvic Floor Disorders
Interventions: OTHER: nill
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Perforated Barrier Membranes and IPRF Nano- Micro Sticky Bone
Status: COMPLETED
Conditions: Bone Augmentation
Interventions: PROCEDURE: Perforated collagen membrane|PROCEDURE: Occlusive collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma?
Status: UNKNOWN
Conditions: Head Trauma|Traumatic Brain Injury|Chronic Subdural Hematoma
Interventions: DRUG: discontinuation of aspirin therapy|DRUG: continuation of aspirin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicentre Phase-IV Clinical Trial of Olaparib in Indian Patients With Ovarian and Metastatic Breast Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Breast Cancer
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-guided CGN for Inoperable Cancer
Status: TERMINATED
Conditions: Intractable Abdominal Pain Secondary to Inoperable Malignancy
Interventions: PROCEDURE: EUS-guided celiac ganglion neurolysis|PROCEDURE: Percutaneous celiac plexus neurolysis|DEVICE: Olympus UM 2000|DEVICE: B-D Quincke Type Point|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foley vs Propess for Induction of Labor in Women With Term PROM : Mode of Delivery, Maternal and Fetal Outcomes
Status: COMPLETED
Conditions: Premature Rupture of Membranes at Term|Mode of Delivery
Interventions: OTHER: Mode of delivery, maternal and neonatal outcomes/complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Community Based Doulas for Migrant Women in Labour and Birth in Sweden - a Randomised Controlled Trial
Status: COMPLETED
Conditions: Labor Pain|Satisfaction, Consumer|Language|Birth Depression|Childbirth Problems
Interventions: OTHER: Community-based doula support for labour|BEHAVIORAL: Standard labour support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry
Status: RECRUITING
Conditions: Peripheral Artery Disease|Popliteal Aneurysm|Hemodialysis Access|Visceral Artery Aneurysms|Trauma Injury
Interventions: DEVICE: GORE® VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface (VSX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Health Service Research Study to Investigate Survival of Metastatic Pancreatic Cancer Patients After Sequential Chemotherapy
Status: TERMINATED
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: OFF|DRUG: FOLFIRI Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Peptide Cancer Vaccine To Treat HLA-A*02-positive Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: HLA-A*0201 or HLA-A*0206-restricted URLC10 peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma
Status: RECRUITING
Conditions: Seminoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Predictors of Coronary Revascularization Outcomes in Type 2 Diabetic Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2 With Acute Coronary Syndrom
Interventions: PROCEDURE: with percutaneous coronary intervention (PCI) are with new-generation drug-eluting stents (DES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized, Controlled Study to Investigate the Effect of Neuromuscular Electrical Stimulation (NMES) on Muscle Metabolism of Abdominal Surgical Patients
Status: COMPLETED
Conditions: Muscular Atrophy
Interventions: DEVICE: neuromuscular electrical stimulation: Cefar-Sport (CefarCompex Scandinavia AB)|DEVICE: neuromuscular electrical stimulation: Cefar-Sport (CefarCompex Scandinavia AB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intermittent Oral-esophageal Tube in Delayed Dysphagia After Radiotherapy for Nasopharyngeal Carcinoma
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: nasogastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modulating the Impact of Critical Events in Early HIV Infection: Effect of ART Initiation and Alcohol Use
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: ART initiation at time of HIV diagnosis|DRUG: ART at 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT