pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase 1 Norwalk Vaccine Study
Status: COMPLETED
Conditions: Norovirus
Interventions: DRUG: Adjuvant/Excipients|DEVICE: placebo|BIOLOGICAL: Norwalk VLP Vaccine|BIOLOGICAL: Norwalk VLP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rgp120/HIV-1MN|BIOLOGICAL: rgp120/HIV-1 SF-2|BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Exercise Study of Two Doses of BMN 110 for Morquio A Syndrome
Status: TERMINATED
Conditions: Mucopolysaccharidosis IVA|Morquio A Syndrome|MPS IVA
Interventions: DRUG: BMN 110|DRUG: BMN 110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of EXOSOME-MSC Therapy to Reduce Hyper-inflammation In Moderate COVID-19 Patients
Status: UNKNOWN
Conditions: SARS-CoV2 Infection
Interventions: DRUG: Exosome-MSC Intravenous injection|DRUG: Placebo Intravenous Injection|DRUG: COVID-19 Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Investigating OM-85-IN Safety and Tolerability in Healthy Volunteers and Mild Allergic Asthma Patients
Status: RECRUITING
Conditions: Allergic Asthma
Interventions: DRUG: OM-85-IN|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Cephalexin for Cellulitis (HI-DOCC)
Status: ENROLLING_BY_INVITATION
Conditions: Cellulitis
Interventions: DRUG: Cephalexin|DRUG: Cephalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin®)(OND003IND)
Status: COMPLETED
Conditions: Methamphetamine Dependence|Cocaine Dependence
Interventions: DRUG: OND-PR002 and MPh-IR|OTHER: Placebo: Two dextrose capsules for Ond-PR002 and MPh-IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telecare Rehabilitation Program in Chronic Low Back Pain With Psychological Retention and Predominant Sociability
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Common phase|OTHER: Telecare rehabilitation|OTHER: Care in Face to Face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Anesthetic Technique on Cerebral Oxygenation During Spinal Surgery
Status: RECRUITING
Conditions: Cerebral Oxygenation
Interventions: DEVICE: sensors of regional cerebral oxygen saturation (O3 regional oximeter, Masimo Corp, Irvine, CA) FDA Reg No. 3011353843
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Hemophagocytic Syndromes
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pharmacotherapeutic Education on Medication Adherence and Adverse Outcomes in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Education|Drug-Related Side Effects and Adverse Reactions
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Intermediate Cervical Plexus Block and Superficial Cervical Plexus Block
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: PROCEDURE: cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis
Status: RECRUITING
Conditions: Acute Bronchiolitis
Interventions: DRUG: Nebulized 3% sodium chloride solution|DEVICE: Chest percussion cups
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of SRT2104 Administered to Normal Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: SRT2104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Observation of Technologic Application of No-touch Fluid-air Exchange in Surgery of Idiopathic Macula Hole
Status: COMPLETED
Conditions: Idiopathic Macula Hole
Interventions: PROCEDURE: no-touch fluid-air exchange|PROCEDURE: vitrectomy metrectomy and internal membrane peeling and gas tamponed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer
Status: COMPLETED
Conditions: Symptomatic, Aggressive, Sporadic, Unresectable, Locally|Advanced/Metastatic Medullary Thyroid Cancer (MTC)
Interventions: DRUG: Vandetanib 300 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiofrequency Ablation Plus Botulinum Toxin Injection Versus Radiofrequency Ablation Only in Patients With Atrial Flutter
Status: UNKNOWN
Conditions: Atrial Flutter
Interventions: PROCEDURE: radiofrequency ablation|DRUG: Botulinum Toxin Type A injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Time to Appropriate Antibiotic Between Using Microarray Assay and Mass Spectrometry Technique
Status: UNKNOWN
Conditions: Septicemia
Interventions: DIAGNOSTIC_TEST: Mass spectrometry|DIAGNOSTIC_TEST: Microarray assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Primary Central Nervous System Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Primary Central Nervous System Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: rituximab|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Gel 2% and Muscle Traction Pain During Squint Surgery in Pediatrics
Status: COMPLETED
Conditions: Squint
Interventions: DRUG: lidocaine gel 2%|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety & Efficacy of Eslicarbazepine Monotherapy in Sub.w/Partial Epilepsy Not Well Controlled by Current Antiepileptic
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Eslicarbazepine acetate 1600 mg|DRUG: Eslicarbazepine acetate 1200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety & Effectiveness of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Placebo nasal spray|DRUG: 0.15% azelastine hydrochloride Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double J Stenting and Sildosin After URSL for Lower Ureteric Stones
Status: COMPLETED
Conditions: Lower Ureteric Stones|Ureteroscopic Lithotripsy|DJ Stenting
Interventions: PROCEDURE: DJ stent|DRUG: Silodosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: erlotinib hydrochloride|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sulfur Water and Mud Therapy on Serotonin Activity and Biochemical Parameters in Patients' Osteoarthrosis
Status: UNKNOWN
Conditions: Osteoarthritis of Multiple Joints
Interventions: OTHER: Mud therapy application|OTHER: Sulfur water application|OTHER: Hygienic water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron Source on the Growth of Enteric Pathogens
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia|Iron Deficiency Anemia Treatment
Interventions: DIETARY_SUPPLEMENT: FeSO4|DIETARY_SUPPLEMENT: Ao iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Accurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Micro Mouth Pressure Meter|DEVICE: Iowa Oral Performance Instrument|DEVICE: Electrical Impedance Myography|DRUG: Capsaicin|PROCEDURE: Videofluoroscopic Swallowing Study|PROCEDURE: Pulmonary Function Testing|OTHER: Swallowing Related Quality of Life Questionnaire|OTHER: Functional Oral Intake Scale|OTHER: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised|OTHER: Eating Assessment Tool-10|OTHER: Communicative Effectiveness Survey|OTHER: The Center for Neurologic Studies Bulbar Function Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System
Status: COMPLETED
Conditions: Skin Irritation|Sensitization
Interventions: DRUG: Donepezil TDS|DRUG: Vehicle TDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Accuracy of Dental Implant Placement Using a Collaborative Surgery Robot
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implant
Interventions: PROCEDURE: Robot system|PROCEDURE: Freehand surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stelara and Diet Trial for Crohn"s Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease
Interventions: OTHER: Crohn's disease exclusion diet (CDED)|DRUG: Ustekinumab Injection [Stelara]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Organ-preservative Therapy of Bladder Cancer With Radiotherapy or Radiochemotherapy Combined With Hyperthermia
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: OTHER: Hyperthermia|RADIATION: Radiotherapy|DRUG: Chemotherapy 5-Fluorouracil|DRUG: Chemotherapy Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Midostaurin|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Pittsburgh Vitamin D Study: Vitamin D Supplementation in Vitamin D-deficient Subjects at Risk of Lung Cancer
Status: TERMINATED
Conditions: Deficiency of Vitamin D3|COPD
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: multivitamin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With Amantadine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: amantadine hydrochloride|DRUG: oseltamivir phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Changes in FDG- and FLT-PET Imaging in Patients With Non-Small Cell Lung Cancer Following Treatment With Erlotinib
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: 2-deoxy-2-[18F]fluoro-D-glucose (FDG)|OTHER: 3'-deoxy-3'-[18F]fluorothymidine (FLT)|DRUG: erlotinib HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Burden of Staphylococcus Lugdunensis Infections in Hospitalized Patients
Status: UNKNOWN
Conditions: Staphylococcus Lugdunensis Infection
Interventions: BIOLOGICAL: Determination of the clinical and biological characteristics|BIOLOGICAL: Description of the antibiotic resistance profile|BIOLOGICAL: Molecular epidemiology of S. lugdunensis infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label, Safety and Efficacy Study of Pulmicort® Turbuhaler® in Japanese Children With Bronchial Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide|DRUG: fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Continuous Vital Sign Monitoring Increase Investigations and Interventions in Complication-free Patients?
Status: RECRUITING
Conditions: Cancer|Chronic Obstructive Pulmonary Disease|Surgery-Complications
Interventions: DEVICE: Active alarms from WARD software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL
Status: ACTIVE_NOT_RECRUITING
Conditions: Anal High Grade Squamous Intraepithelial Lesion|Anal Precancerous Condition|AIN 2/3|HPV Infection|Anal Dysplasia|HPV Disease
Interventions: DRUG: Artesunate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurally Adjusted Ventilatory Assist (NAVA) in Patients With Critical Illness Associated Polyneuropathy / or Polymyopathy (CIP/M)
Status: COMPLETED
Conditions: Polyneuropathy|Polymyopathy
Interventions: DEVICE: Neurally adjusted ventilatory assist (NAVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Nivolumab and Ipilimumab, Followed by Post-operative Nivolumab, for MSI/dMMR Oeso-gastric Adenocarcinoma.
Status: RECRUITING
Conditions: Localized Oesogastric Adenocarcimona|MSI and or dMMR
Interventions: DRUG: Nivolumab 10 MG/ML|DRUG: Ipilimumab 200 MG in 40 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF LOW LEVEL LASER THERAPY VERSUS ELECTROACUPUNCTURE ON POSTNATAL SCANTY MILK SECRETION
Status: COMPLETED
Conditions: Insufficient Lactation
Interventions: DRUG: domperidone|DEVICE: He-Ne laser (Bravo TrezaSerie) device|DEVICE: faradic current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control Of Fluid Balance Guided by Body Composition Monitoring in Patients on PeritoneAl dialySiS
Status: COMPLETED
Conditions: Peritoneal Dialysis, Continuous Ambulatory
Interventions: DEVICE: BCM-guided fluid management|PROCEDURE: Fluid management based on the clinical information alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Diquafosol tetrasodium ophthalmic solution, 2%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intervention for Adolescents With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: BEHAVIORAL: Patient information and education|OTHER: Information, education and physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Renal Colic
Interventions: DRUG: Acetaminophen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Pudendal Nerve Block for Pain After Hemorrhoidectomy
Status: RECRUITING
Conditions: Hemorrhoids|Postoperative Pain
Interventions: PROCEDURE: Pudendal nerve block|PROCEDURE: Placebo block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of GRF6019 Infusions in Subjects With Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Severe Alzheimer Disease
Interventions: DRUG: GRF6019|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bumetanide Versus Furosemide in Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: DRUG: Furosemide|DRUG: Bumetanide|DRUG: furosemide|DRUG: bumetanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Rituximab Against Mycophenolate Mofetil in Children Wtih Refractory Nephrotic Syndrome
Status: TERMINATED
Conditions: Frequent Relapsing Nephrotic Syndrome|Steroid Dependent Nephrotic Syndrome
Interventions: DRUG: Rituximab|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occluded Artery Trial (OAT)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Myocardial Infarction|Heart Failure, Congestive|Heart Failure
Interventions: DRUG: Beta adrenergic blockers|DRUG: Platelet inhibitors|PROCEDURE: PTCA and stents|DRUG: ACE Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Relief for Submucosal Resection of Nasal Septum in Adults Does Ketamine Have a Pre-Emptive Effect?
Status: WITHDRAWN
Conditions: Nasal Obstruction
Interventions: DRUG: Ketamine i.v
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of SAR421869 in Participants With Retinitis Pigmentosa Associated With Usher Syndrome Type 1B
Status: TERMINATED
Conditions: Usher Syndrome|Retinitis Pigmentosa
Interventions: DRUG: SAR421869
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study
Status: COMPLETED
Conditions: Opioid Use Disorder|Alcohol Use Disorder
Interventions: DRUG: Extended Release Naltrexone|OTHER: Treatment As usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain
Status: UNKNOWN
Conditions: Myofacial Pain
Interventions: DRUG: Gabapentin|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pidnarulex and Talazoparib in Patients With Metastatic Castration Resistant Prostate Cancer
Status: SUSPENDED
Conditions: Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Pidnarulex|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anti-BCMA-GPRC5D CAR-T Cells Therapy in the Treatment of r/r MM
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Anti-BCMA-GPRC5D CAR-T cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Digital Active Aging Training Program for Older Adults
Status: RECRUITING
Conditions: Healthy Aging|Cognitive Change|Psychological Stress|Loneliness|Social Interaction
Interventions: BEHAVIORAL: Resilience training|BEHAVIORAL: cognitive training|BEHAVIORAL: physical exercise|BEHAVIORAL: social interaction|BEHAVIORAL: workshop series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Durvalumab and Tremelimumab in Treating Participants With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: RECRUITING
Conditions: Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Refractory Fallopian Tube Carcinoma|Refractory Ovarian Carcinoma|Refractory Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Durvalumab|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myoelectric Activity of Upper Trapezius Trigger Point
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: DEVICE: extracorporeal shock wave and conventional treament|DEVICE: high pain threshold ultrasound and conventional treatment for myofascial pain syndrome trigger points|OTHER: conventional treatment for myofascial pain trigger point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neurological Injury|Paralysis|Spasticity, Muscle
Interventions: BEHAVIORAL: Spinal Reflex Operant Down Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Quality of Life in School Aged-children With Posterior Urethral Valves
Status: NOT_YET_RECRUITING
Conditions: Quality of Life|Posterior Urethral Valve|Renal Insufficiency|Chronic Renal Disease|End Stage Renal Disease|Bladder Dysfunction|Urinary Incontinence
Interventions: OTHER: Children with PUV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Intensity Interval Training Versus Intermittent Fasting on Functional Capacity Among Overweight Subjects
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: High Intensity Interval Training|OTHER: Intermittent Fasting 16/8 Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHF-COV Reduced (Chronic Heart Failure With Reduced Ejection Fraction - COngestion eValuation)
Status: RECRUITING
Conditions: Chronic Heart Failure|Reduced Ventricular Ejection Fraction
Interventions: PROCEDURE: Clinical examination centered on congestion|PROCEDURE: Cardiac, pulmonary, peritoneal, jugular and renal Doppler ultrasounds|PROCEDURE: Blood sample retrieved for biological assessment and biobanking|OTHER: Telephone follow-up|BEHAVIORAL: Kansas City Cardiomyopathy Questionnaire (KCCQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Precise DCE-MRI in Diagnosing Participants With Recurrent High Grade Glioma or Melanoma Brain Metastases
Status: TERMINATED
Conditions: Brain Metastases|Glioma of Brain|Brain Tumor|Metastatic Melanoma
Interventions: DEVICE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|DRUG: Bevacizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improving Weight Loss Outcomes for Binge Eating Disorder.
Status: COMPLETED
Conditions: Eating Disorder|Binge-Eating Disorder|Weight Loss|Binge Eating
Interventions: BEHAVIORAL: Acceptance-Based Behavioral Weight Loss Therapy for BED|BEHAVIORAL: Standard Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lactobacillus Reuteri Probiotic as an Adjunct Treatment for Helicobacter Pylori Infection in Adults
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17648 probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Suppression of Cutaneous Allergic Responses and Pruritus by Topical Doxycycline
Status: UNKNOWN
Conditions: Hives
Interventions: DRUG: 2% Doxycycline Cream in Generic Aquaphor or Generic Aquaphor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib Plus Rituximab for Patients With Indolent Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVarQuit: Extended Pre-quit Varenicline to Assist in Quitting Smoking
Status: COMPLETED
Conditions: Tobacco Smoking
Interventions: DRUG: Varenicline|BEHAVIORAL: Brief smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pulpal Anesthesia and Patient Preference Using the Needle-less and Conventional Injection Techniques
Status: NOT_YET_RECRUITING
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DEVICE: Needle-less jet anaesthesia|DEVICE: Conventional Injection Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Complete Remission After Treatment With Selumetinib/Placebo in Patient With Differentiated Thyroid Cancer
Status: TERMINATED
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Selumetinib|DRUG: Placebo|DRUG: Radioactive Iodine Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroids Versus Non-steroidal Anti-inflammatory Drugs Following Glaucoma Surgery
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Ketorolac (NSAID) versus Dexamethasone (steroid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Granulocyte Colony Stimulating Factor (GCSF) In Patients With Dystrophic Epidermolysis Bullosa
Status: COMPLETED
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Granulocyte Colony Stimulating Factor (GCSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Emtricitabine/Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automated Insulin Delivery in Elderly With Type 1 Diabetes (AIDE T1D)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Tandem t:slim X2 with HCL or PLGS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remaxol® in Malignant Mechanical Jaundice
Status: COMPLETED
Conditions: Jaundice; Malignant
Interventions: DRUG: Remaxol®|DRUG: Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Gut Hormones and Inflammatory Adipokines in Obese Patients Underwent Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Chronic Inflammation|Type 2 Diabetes
Interventions: PROCEDURE: laparoscopic Roux-en-Y gastric bypass|PROCEDURE: laparoscopic sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Weekly Paclitaxel (BMS-181339) in Patient With Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Intravenous (IV) Paricalcitol (Zemplar) on Cardiac Morbidity in Patients With Chronic Kidney Disease (CKD) Stage 5 Over 2 Years
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease Stage V|Cardiac Morbidity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of "Smart Wheelchairs" to Provide Independent Mobility to Visual and Mobility Impairments
Status: COMPLETED
Conditions: Blindness|Spinal Cord Injury
Interventions: DEVICE: Smart Power Assistance Module (SPAM)|DEVICE: Smart Wheelchair Component System (SWCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stroke Volume Optimisation in Patients With Hip Fracture
Status: TERMINATED
Conditions: Hip Fractures
Interventions: PROCEDURE: hemodynamic optimisation guided using esophageal Doppler|DRUG: VOLUVEN and others solute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Baseline Visual Acuity on the Treatment Outcomes in Patients Treated With AflIbercept in Real-life Clinical Setting
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Holmium-166 Transarterial Radioembolization in Unresectable, Early Stage Hepatocellular Carcinoma.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Holmium-166 treatment|DEVICE: Holmium-166 work-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inferior Oblique Muscle Anteriorization Versus Anteriorization and Resection in DVD With IOOA
Status: COMPLETED
Conditions: Dissociated Vertical Deviation|Inferior Oblique Overaction
Interventions: PROCEDURE: Inferior oblique anteriorization|PROCEDURE: Inferior oblique anteriorization together with unliateral resction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dime La VerDAD: Verify, Debunk, and Disseminate
Status: RECRUITING
Conditions: Misinformation|Influenza|COVID-19|Vaccine Hesitancy|Communication Research|Health Behavior
Interventions: BEHAVIORAL: Science Communication Curriculum Cohort 1|BEHAVIORAL: Science communication curriculum Cohort 2|BEHAVIORAL: Science communication curriculum Cohort 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS)
Status: WITHDRAWN
Conditions: Short Bowel Syndrome
Interventions: DRUG: Liraglutide Pen Injector [Victoza]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Predictive Accuracy of an In-Home Computer Controlled Mandibular Positioner in Identifying Favorable Candidates for Oral Appliance Therapy
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Computer controlled mandibular positioner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetic Study Comparing VI-0521 With Placebo in Obese Adolescents
Status: COMPLETED
Conditions: Pediatric Obesity|Childhood Obesity
Interventions: DRUG: Placebo|DRUG: VI-0521 Mid Dose|DRUG: VI-0521 Top Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interdisciplinary Perioperative Care in Minimally-invasive Heart Valve Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Valve Diseases
Interventions: OTHER: Enhanced Recovery After Surgery|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparision of Collagen Matrix and Connective Tissue Graft With Modified Coronally Advanced Tunnel for Root Coverage
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: root coverage with collagen matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Clinical Trial of an Alphavirus Replicon Vaccine for Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: AVX502|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Compound Sodium Alginate Oral Suspension Sachet Symptomatic Relief Study
Status: COMPLETED
Conditions: Gastro-esophageal Reflux Disease (GERD)
Interventions: DRUG: Compound Sodium Alginate Oral Suspension sachet|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Two Different Physical Therapy Programs in the Rehabilitation of Patients Undergoing Anterior Approach Hip Replacement Surgery
Status: UNKNOWN
Conditions: Hip Arthritis|Total Hip Arthroplasty
Interventions: OTHER: Formal Physical Therapy|OTHER: Self-directed Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Propacetamol, Ibuprofen or Their Combination on Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: ibuprofen (caldolor 10 mg / kg)|DRUG: propacetamol (denogan 30 mg / kg)|DRUG: ibuprofen + propacetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2|Renal Insufficiency
Interventions: DRUG: GSK189075
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Treatment Regimens in Treating Patients With Relapsed or Refractory Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: gemtuzumab ozogamicin|DRUG: liposomal daunorubicin citrate|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety & Reactogenicity of GSK Biologicals' dTpa Vaccine (Boostrix) When Given at 6-8 Years of Age.
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Acellular Pertussis
Interventions: BIOLOGICAL: Boostrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Donor Lymphocytes|DRUG: Guadecitabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Social Presence and Perception in Virtual Reality on Pain
Status: COMPLETED
Conditions: Chronic Pain, Widespread
Interventions: OTHER: Near Non-Social|OTHER: Near Social|OTHER: Far Non-Social|OTHER: Far Social
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Algorithm to identify patients experiencing opioid abuse/addiction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease|Mindfulness Based Stress Reduction|Quality of Life
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|BEHAVIORAL: Creative Education Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine as an Adjunctive Therapy for Major Depression
Status: COMPLETED
Conditions: Major Depressive Episode|Unipolar Depression|Bipolar Depression
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Needle-embedding Therapy Alleviates Depressive Symptoms and Resets the Function of Executive Control System in Subthreshold Depression People
Status: UNKNOWN
Conditions: Subthreshold Depression
Interventions: PROCEDURE: needle-embedding therapy|DEVICE: shame needle-embedding therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)
Status: COMPLETED
Conditions: Endometrial Cancer|Uterine Carcinosarcoma
Interventions: DRUG: Rucaparib|DRUG: Bevacizumab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ecosystem Focused Therapy for Treating Older Depressed Stroke Survivors
Status: COMPLETED
Conditions: Ischemic Stroke|Depression
Interventions: BEHAVIORAL: Ecosystem Focused Therapy (EFT)|BEHAVIORAL: Education in stroke and depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Explore the Safety, Tolerability, and Preliminary Antitumor Activity of Sitravatinib Plus Tislelizumab or Combination With Nab-paclitaxel in Patients With Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Sitravatinib|DRUG: Tislelizumab|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-Based Lifestyle Intervention for the Improvement of Health in African American Cancer Survivors
Status: WITHDRAWN
Conditions: Cancer Survivor
Interventions: BEHAVIORAL: Lifestyle Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 28-week Safety Study of Flibanserin in Pre- and Postmenopausal Women With Hypoactive Sexual Desire Disorder
Status: TERMINATED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: flibanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Compared With Placebo in the Treatment of Manic Episodes Associated With Bipolar I Disorder, and the Maintenance of Anti-manic Effectiveness of Risperidone Compared With Haloperidol
Status: COMPLETED
Conditions: Bipolar Disorders|Manic Disorder
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum
Status: COMPLETED
Conditions: Cardiac Toxicity|Malignant Neoplasm|Breast Cancer
Interventions: PROCEDURE: Magnetic resonance imaging|OTHER: Physical Activity|OTHER: Healthy Living|DEVICE: Cardiopulmonary Exercise Testing (CPET)|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
Status: RECRUITING
Conditions: Cardiac Resynchronization Therapy|Chronic Heart Failure|Left Bundle-Branch Block
Interventions: DEVICE: CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION