pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rituximab and LMP-Specific T-Cells in Treating Pediatric Solid Organ Recipients With EBV-Positive, CD20-Positive Post-Transplant Lymphoproliferative Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: EBV-Related Post-Transplant Lymphoproliferative Disorder|Monomorphic Post-Transplant Lymphoproliferative Disorder|Polymorphic Post-Transplant Lymphoproliferative Disorder|Recurrent Monomorphic Post-Transplant Lymphoproliferative Disorder|Recurrent Polymorphic Post-Transplant Lymphoproliferative Disorder|Refractory Monomorphic Post-Transplant Lymphoproliferative Disorder|Refractory Polymorphic Post-Transplant Lymphoproliferative Disorder
Interventions: BIOLOGICAL: Allogeneic LMP1/LMP2-Specific Cytotoxic T-Lymphocytes|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caregiver Contribution to Self-Care in Ostomy Patient Index: Turkish Validity and Reliability Study
Status: COMPLETED
Conditions: Stoma Colostomy|Stoma Ileostomy|Caregiver|Self Care
Interventions: BEHAVIORAL: Caregiver Contribution to Self-Care in Ostomy Patient Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Stroke, Acute|Brain Injury, Acute
Interventions: BIOLOGICAL: Umbilical Cord Blood|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Involvement of Polyomaviruses in the Pathogenesis of Autoimmune Thyroiditis and Goitrigenesis.
Status: UNKNOWN
Conditions: Polyoma Virus Infection|Thyroiditis, Autoimmune
Interventions: OTHER: Comparison of Positive PCR Frequencies for Polyomavirus in Blood, Urine and / or Thyroid Tissue vs Basedow / Hashimoto
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety and Immune Response to a Dengue Virus Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: rDEN2Δ30-7169 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacotoxicology of Trichloroethylene Metabolites
Status: COMPLETED
Conditions: Congenital Lactic Acidosis
Interventions: DRUG: Dichloroacetate (DCA)|GENETIC: Genetic Marker on Chromosome 14q24.3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Hypoglycemia
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antitumor Efficacy of Peptide Receptor Radionuclide Therapy With 177Lutetium -Octreotate Randomized vs Sunitinib in Unresectable Progressive Well-differentiated Neuroendocrine Pancreatic Tumor: First Randomized Phase II
Status: UNKNOWN
Conditions: Pancreatic Neuroendocrine Carcinoma
Interventions: DRUG: Sunitinib|DRUG: 177Lu-DOTA0-Tyr3-Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Allogenic Adoptive Immune Therapy for Advanced AIDS Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Immunodeficiency
Interventions: COMBINATION_PRODUCT: Conventional plus AAIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Glycemic Control on Skeletal Outcomes in Adults With Type 1 Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 1|Bone Health|Bone Loss|Bone Diseases, Metabolic|Hyperglycaemia Due to Type 1 Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Clinical tests|DIAGNOSTIC_TEST: Biochemical tests|DIAGNOSTIC_TEST: DXA scan with TBS and VFA|DIAGNOSTIC_TEST: AGEReader
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Drug Drug Interaction (DDI) Study of Selpercatinib and Dabigatran in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran|DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Status: COMPLETED
Conditions: Chronic Granulomatous Disease|Communicable Disease
Interventions: DRUG: Gene Therapy Method for CGD|DEVICE: Isolex 300i Magnetic Cell Selector
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Postprandial Effects of Chick-Pea Consumption on Glucose, Insulin, and Gut Hormone Responses (PEA-POD).
Status: COMPLETED
Conditions: Postprandial Period
Interventions: DIETARY_SUPPLEMENT: Chickpea powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise and Diet Intervention Attenuated Inflammation Through ASC Gene and Inflammatory Markers in Obese Adults
Status: COMPLETED
Conditions: Inflammatory Response|Obesity|Abdominal Obesity|Diet Habit|Exercise
Interventions: BEHAVIORAL: Exercise-Diet Intervention|BEHAVIORAL: Diet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy WC3011 (Estradiol Vaginal Cream) in the Treatment of Vulvovaginal Atrophy in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Vulvovaginal Atrophy
Interventions: DRUG: WC3011 Estradiol Vaginal Cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Single Subretinal Injection of JWK006 Gene Therapy in Subjects With Stargardt Disease(STGD1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Stargardt Disease 1
Interventions: GENETIC: JWK006
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How BI 1265162 is Taken up and Processed by the Body
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: Part 1: BI 1265162 - intravenous|DRUG: Part 2: BI 1265162 - oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance
Status: RECRUITING
Conditions: Carbohydrate Intolerance
Interventions: OTHER: Low-FODMAP diet group (LFD)|OTHER: Low Sugar diet group (LAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Ureteral Stents Length and Location on Related Symptom
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Overactive Bladder Syndrome
Interventions: DEVICE: Ureteral Stent of 5-16 or 5-18|DEVICE: Ureteral Stent of 5-22 or 5-24
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma; Eosinophilic|Asthma
Interventions: DRUG: Lipopolysaccharides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 2 Dose Neuraxial Morphine for Prevention of PDPH
Status: SUSPENDED
Conditions: Postdural Puncture Headache
Interventions: DRUG: Morphine|DRUG: Sterile normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training and Fat Metabolism in Postmenopausal Women
Status: RECRUITING
Conditions: Postmenopausal Symptoms|Obesity|Prediabetic State
Interventions: BEHAVIORAL: Resistance Exercise|BEHAVIORAL: Endurance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
Status: UNKNOWN
Conditions: Arthroscopic Knee Surgery|Lower Limb Fractures|Back Pain and Asymmetric Gait|Complex Regional Pain Syndrome
Interventions: OTHER: Soft surface|OTHER: Floor|OTHER: Kyboot shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Pharmacological Treatments of Pedophilia
Status: TERMINATED
Conditions: Pedophilia
Interventions: DRUG: leuprorelin|DRUG: Cyproterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Camrelizumab (SHR-1210) and Apatinib for Downstaging/Bridging of HCC Before Liver Transplant
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Transplant
Interventions: DRUG: Camrelizumab plus apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare PK, PD and Safety of the AD-214 and AD-2141
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AD-214|DRUG: AD-2141
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Psoriasis Plaque Test Study With Different Dose Combinations of Calcipotriol Plus Betamethasone Dipropionate in the Daivobet® Gel Vehicle in Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus BDP gel in different doses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Kinesio Taping Versus Compression Garments for Breast Cancer-Related Lymphedema
Status: COMPLETED
Conditions: Breast Cancer Lymphedema
Interventions: OTHER: Kinesio Taping|OTHER: Compression Garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Screening for Immunotherapy Response Evaluation Using Microneedle Patch in Patients With Allergic Rhinitis
Status: RECRUITING
Conditions: Rhinitis, Allergic
Interventions: OTHER: Evaluation of clinical indicators, Sample collection before& after immunotherapy|OTHER: Sample collection before& after immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-step Functional Sinus Endoscopy and Transoral Surgery
Status: RECRUITING
Conditions: Maxillary Sinusitis
Interventions: PROCEDURE: Single-step Functional Sinus Endoscopy and Transoral Surgery|PROCEDURE: Functional sinus endoscopy|PROCEDURE: Trans oral Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: BIOLOGICAL: ABvac40|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of SPD503 and Concerta Administered Alone and In Combination in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SPD503|DRUG: Concerta|DRUG: SPD503 + Concerta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
Status: COMPLETED
Conditions: White Spot Lesion of Tooth
Interventions: OTHER: CPP-ACP paste|OTHER: Fluoride toothpaste|OTHER: Both (Fluoride and CPP-ACP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pancreatic Polypeptide on Insulin Requirements for Type 1 & Post-pancreatectomy Diabetic Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Placebo|DRUG: Pancreatic Polypeptide (PP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of IFX-1 in Patients With Moderate to Severe Hidradenitis Suppurativa (HS)
Status: COMPLETED
Conditions: Hidradenitis Suppurativa (HS)
Interventions: DRUG: IFX-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HRV Biofeedback in Pain Patients
Status: COMPLETED
Conditions: Chronic Neuromuscular Pain
Interventions: BEHAVIORAL: active heart rate variability biofeedback training|BEHAVIORAL: sham HRVB training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMDR Psychotherapy to Treat Anxious-depressive Symptoms in Breast Cancer Patient
Status: COMPLETED
Conditions: Breast Cancer|Eye Movement Desensitization and Processing|Psychoterapy
Interventions: BEHAVIORAL: EMDR psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Computed Tomography Coronary Angiography for the Prevention of Myocardial Infarction (The SCOT-HEART 2 Trial)
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Computed tomography coronary angiography|OTHER: ASSIGN Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: Biological: mRNA-1273|BIOLOGICAL: Placebo|BIOLOGICAL: mRNA-1273.351
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open Label, Prospective Study of the Analgesic Efficacy of Oral Xartemis Compared to Generic Oxycodone/APAP( Acetaminophen) in the Treatment of Moderate to Severe Post Operative Pain.
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Percocet|DRUG: Xartemis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors
Status: SUSPENDED
Conditions: Solid Tumor
Interventions: DRUG: Atezolizumab|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety And Efficacy Study Of Alg-1001 In Human Subjects With Symptomatic Focal Vitreomacular Adhesion
Status: COMPLETED
Conditions: Symptomatic Focal Vitreomacular Adhesion
Interventions: DRUG: 2.0mg of ALG-1001|DRUG: Balanced Salt Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Local drug delivery|DRUG: curcumin gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Performance of an Injectable Hyaluronic Acid Filler
Status: COMPLETED
Conditions: Lips Enhancement|Nasolabial Fold Correction|Midface Volume Deficit
Interventions: DEVICE: HLR-1|DEVICE: HLR-2|DEVICE: HLR-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar-capillary Reserve After Exercise in Chronic Obstructive Pulmonary Disease (COPD) (COP-DTPA)
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Acute exercise bout on visit 2 and 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sleep Apnea Treatment With Expiratory Resistance(Provent™)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Treatment sleep study (Provent™ device used)|OTHER: Baseline sleep study (No device)|OTHER: Physiology sleep study (Provent™ on/off)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: GAMALINE®+HIPERICIN® for PMS Treatment and Vasomotor Symptoms
Status: UNKNOWN
Conditions: Premenstrual Syndrome|Uterus; Hemorrhage, Preclimacteric or Premenopausal
Interventions: DRUG: GAMALINE® + HIPERICIN®|DRUG: GAMALINE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between "Conventional Monitoring" Versus "Monitoring Via Vitaphone" in the Detection of Post Ablation Atrial Arrhythmias of Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: ECG monitoring & record|OTHER: Conventional follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Herceptin (Trastuzumab) in Combination Chemotherapy in Patients With Metastatic or Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab|DRUG: paclitaxel|DRUG: Myocet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease
Status: RECRUITING
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|End Stage Renal Disease
Interventions: OTHER: Discontinuation (or not initiation) of Immunosuppressive Therapy|DRUG: Maintenance (or initiation) of immunosuppressive treatment: Imurel®, Mabthera®,Cellcept®, Cortancyl®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Consuming Protein Shakes, Varying in Protein Source, on Appetite, Satiety and Energy Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Water Preload Drink|DIETARY_SUPPLEMENT: Whey Protein Isolate Drink|DIETARY_SUPPLEMENT: Micellar Casein Protein Drink|DIETARY_SUPPLEMENT: Egg White Isolate Protein Drink|DIETARY_SUPPLEMENT: Egg White Concentrate Protein Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Al18F-NOTA-octreotide PET Imaging of the Somatostatin Receptor in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Al18F-NOTA-octreotide|DEVICE: PET/CT|OTHER: Venous blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Study of Metronidazole to Treat Dientamoebiasis in Children
Status: COMPLETED
Conditions: Dientamoebiasis
Interventions: DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-05280014 [Trastuzumab-Pfizer] Or Herceptin® [Trastuzumab-EU] Plus Paclitaxel In HER2 Positive First Line Metastatic Breast Cancer Treatment (REFLECTIONS B327-02)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: PF-05280014|DRUG: Paclitaxel|BIOLOGICAL: Herceptin®|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulating the Stress Response in Diabetes Mellitus Type 2 Patients Undergoing Colon Surgery
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Insulin Resistance
Interventions: PROCEDURE: Intensified insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs
Status: RECRUITING
Conditions: Osteonecrosis of the Jaw|Osteonecrosis Due to Drugs, Jaw|Osteonecrosis Due to Drug|Bisphosphonate-Associated Osteonecrosis|Bisphosphonate-Associated Osteonecrosis of the Jaw
Interventions: PROCEDURE: Dental management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Cediranib|DRUG: Bevacizumab|DRUG: 5-fluorouracil ( in FOLFOX)|DRUG: Leucovorin (in FOLFOX)|DRUG: Oxaliplatin (in FOLFOX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antegrade Observational Comparative Study for the Intravesical Instillation Therapy of Bacillus Calmette Guerin With the Use of Different Types of Urinary Catheters in Patients With Urinary Bladder Cancer
Status: COMPLETED
Conditions: Non-muscle-invasive Bladder Cancer
Interventions: DRUG: BCG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle Hypertrophy
Status: COMPLETED
Conditions: Muscle Hypertrophy in Healthy Young Men
Interventions: DRUG: Salbutamol|DRUG: Placebo|OTHER: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Recombinant Human Activated Coagulation Factor VII for Injection in Patients With Hemophilia With Inhibitor
Status: UNKNOWN
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: Recombinant human activated coagulation factor VII for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Effect of REGENETEN Bioinductive Implant in the Supraspinatus Tendon Repair.
Status: ACTIVE_NOT_RECRUITING
Conditions: Supraspinatus Tear
Interventions: DEVICE: REGENETEN Bioinductive Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)
Status: RECRUITING
Conditions: Niemann-Pick Diseases|Acid Sphingomyelinase Deficiency
Interventions: DRUG: Olipudase alfa
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RFA for Small HCC With No-touch Technique and Dual Cooled-Wet Electrode
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: No-touch RFA arm|PROCEDURE: Conventional tumor puncture RFA arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Scapula Mobilization on Mechanosensitivity of Upper Limb Neural Test 1 in Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Musculoskeletal Diseases
Interventions: OTHER: Interscapular muscle release or scapular mobilization technique as described by Travell and Simons.|OTHER: Calcaneus abduction and adduction mobilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: DRUG: Cromoglycate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Use of the Complex in Gel for Healing of Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcer|Wound
Interventions: DRUG: Gel with HPβCD-I complex|DRUG: Gel with insulin|DRUG: Control gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Morning Operation and Evening Operation on Postoperative Sleep Quality and Pain Under General Anesthesia
Status: COMPLETED
Conditions: Morning Operation|Evening Operation|Sleep Quality|General Anesthesia|Circadian Rhythm Sleep Disorder
Interventions: OTHER: receiving operation during the day or at night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Milk Patch for Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis|Milk Allergy
Interventions: DRUG: Viaskin Milk 500 mcg|DRUG: Viaskin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Deep Caries|Pulp Exposure, Dental
Interventions: DRUG: RetroMTA|DRUG: TheraCal|DRUG: Fuji IX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Assess Resiniferatoxin vs Standard of Care for the Treatment of Intractable Cancer Pain
Status: WITHDRAWN
Conditions: Pain, Intractable|Pain Cancer
Interventions: DRUG: Resiniferatoxin|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant
Status: TERMINATED
Conditions: Acute Myeloid Leukemia and Myelodysplastic Syndrome
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome
Status: TERMINATED
Conditions: Restless Leg Syndrome
Interventions: DRUG: Gabapentin immediate release|DRUG: Gabapentin enacarbil extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I-Scan a Novel Endoscopic Tool for the Macroscopic Identification of Mucosal Lesions
Status: COMPLETED
Conditions: Endoscopy
Interventions: DEVICE: I-Scan|DIAGNOSTIC_TEST: Standard endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Functional Exercise on Fitness and QoL in Cancer Survivors
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: OTHER: Functional Resistance Training|BEHAVIORAL: Unsupervised activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Nerve Block Pain Management in Patients Undergoing a Double Mastectomy With Immediate Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female
Interventions: DRUG: PVB Protocol|DRUG: PECS-1|DRUG: Serratus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating HCV and HIV Screening During the Era of HIV Antigen Testing
Status: COMPLETED
Conditions: HIV|Hepatitis C
Interventions: BEHAVIORAL: Questionnaire|PROCEDURE: Rapid finger stick|PROCEDURE: Venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants
Status: COMPLETED
Conditions: Invasive Mucormycosis|Invasive Aspergillosis
Interventions: DRUG: Isavuconazonium sulfate|DRUG: Isavuconazonium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Umbilical Cord Blood Mononuclear Cells Transfusion in Neonates
Status: UNKNOWN
Conditions: Safety Issues|Effect of Drugs|Neonatal Death
Interventions: OTHER: Autologous Umbilical Cord Blood Mononuclear Cells Therapy|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Uniglide™ Mobile Bearing Unicondylar Knee System vs the Uniglide™ Fixed Bearing Unicondylar Knee System
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: Uniglide Mobile Bearing Unicondylar Knee System|DEVICE: Uniglide Fixed Bearing Unicondylar Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation in Sport Performance and Gut Damage
Status: COMPLETED
Conditions: Sport Performance|Gut Damage
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Northern Europe The TRANS-North Study
Status: COMPLETED
Conditions: Diabetic Foot Ulcer of Neuropathic Origin
Interventions: DRUG: Trafermin 0.01% spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored MgSO4 Supplementation to Reduce Complications in Pediatric Heart Surgery
Status: NOT_YET_RECRUITING
Conditions: AKI - Acute Kidney Injury|Arrythmia|Congenital Heart Disease
Interventions: DIAGNOSTIC_TEST: total magnesium|DEVICE: ionized magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age.
Status: COMPLETED
Conditions: Intraoperative Arterial Hypotension|Infant, Newborn
Interventions: DRUG: Ephedrine 30mg/10mL injectable solution, single administration, dose : 0.6, 0.8, 1.0, 1.2 and 1.4 mg/kG|DRUG: Ephedrine 30mg/10mL injectable solution, single administration, dose : 0.1 mg/kG.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Micronized and ultra-micronized Palmitoylethanolamide (mPEA and umPEA, 300mg + 600mg) oral suspension|COMBINATION_PRODUCT: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Efficacy of vBloc Therapy Delivered by the Maestro Rechargeable System for the Treatment of Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: vBloc (Active Device)|DEVICE: Sham (Non-active Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Adding Thoracic Paravertebral Nerve Blocks to Modified PEC Block in Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast Cancer Female|Pain, Postoperative
Interventions: PROCEDURE: Thoracic paravertebral block under ultrasound guidance|PROCEDURE: Intraoperative modified PEC block|PROCEDURE: GA with ETT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: KHK6640|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Ion Radiation Therapy in the Treatment of Mucous Melanomas of the Female Lower Genital Tract
Status: RECRUITING
Conditions: Malignant Melanoma|Gynecologic Cancer
Interventions: RADIATION: carbon ion radiation therapy CIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis.
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: PA-824|DRUG: bedaquiline|DRUG: moxifloxacin|DRUG: pyrazinamide|DRUG: isoniazid, rifampicin, pyrazinamide and ethambutol combination tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Platelet-rich Fibrin to Autologous Fat Tissue in Injection Laryngoplasty for Vocal Cord Paralysis
Status: COMPLETED
Conditions: Vocal Cord Paralysis
Interventions: COMBINATION_PRODUCT: Injection Laryngoplasty with Platelet-rich Fibrin and Autologous Fat|PROCEDURE: Injection Laryngoplasty with Autologous Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on the Correlation Between Immunoglobulin and Liposomal Doxorubicin in Vivo
Status: UNKNOWN
Conditions: Advanced Malignant Tumors
Interventions: DRUG: doxorubicin hydrochloride liposome injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Spastic Splint With Focal Muscle Vibration for Stroke Hand Spasticity
Status: NOT_YET_RECRUITING
Conditions: Spasticity as Sequela of Stroke
Interventions: OTHER: Vibration plus anti-spastic hand splint|OTHER: Anti-spastic hand splint|OTHER: Vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Yoga and Progressive Muscle Relaxation Exercise Practices on Premenstrual Syndrome
Status: UNKNOWN
Conditions: Premenstrual Syndrome
Interventions: BEHAVIORAL: Yoga and Muscle Relaxation Exercise Practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Tigecycline in Selected Serious Infections Caused by Vancomycin-Resistant Enterococcus (VRE) or Methicillin-Resistant Staphylococcus Aureus (MRSA)
Status: COMPLETED
Conditions: Gram-Positive Bacterial Infections|Staphylococcus Infections|Vancomycin Resistance|Methicillin Resistance
Interventions: DRUG: Tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture on Modifying Inflammatory Levels of Cytokines and Metabolites in Stroke Patients.
Status: ENROLLING_BY_INVITATION
Conditions: Ischemic Stroke|Acute
Interventions: DEVICE: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Ribavirin Based Regimens in Patients With Chronic Hepatitis C With Previous Treatment Failure
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Pegylated Interferon alfa-2a|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Recurrent Melanoma|Recurrent Renal Cell Cancer|Stage IV Melanoma|Stage IV Renal Cell Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bryostatin 1|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Intervention and Associated Changes in the Gut Microbiome and Vitamin D Levels in Healthy Adults
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin D intervention|DIETARY_SUPPLEMENT: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Single Groin and Single Trans-septal Puncture and Conventional Bilateral Groin Puncture and Double Trans-septal Puncture in Catheter Ablation for Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: single trans-septal puncture|PROCEDURE: conventional bilateral groin puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability, and PK of DVS SR in Healthy Japanese Women
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: desvenlafaxine succinate sustained release (DVS SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Atherectomy and Drug-Coated Balloon Angioplasty in Treatment of Long Infrapopliteal Lesions
Status: COMPLETED
Conditions: Peripheral Artery Disease|Occlusion of Artery
Interventions: PROCEDURE: paclitaxel-coated balloon angioplasty|PROCEDURE: atherectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth and Safety Study of an Infant Formula for Healthy Term Infants
Status: COMPLETED
Conditions: Infant Development
Interventions: OTHER: BBN|OTHER: Brand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Pembrolizumab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mind-Body Medicine Day Care Clinic in Breast Cancer Patients Undergoing Endocrine Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Mind body medicine day care clinic|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal for Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Bupivacaine with Fentanyl (Spinal Anesthesia)|DRUG: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Fuchs Endothelial Corneal Dystrophy
Interventions: DRUG: STN1010904 ophthalmic suspension 0.03% BID|DRUG: STN1010904 ophthalmic suspension 0.1% BID|DRUG: Placebo (Vehicle) BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Treatment of Peripheral Nerve Defects With Neuromaix
Status: COMPLETED
Conditions: Patients With a Scheduled (Diagnostic) Nervus Suralis Biopsy
Interventions: DEVICE: Neuromaix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Gemcitabine Hydrochloride, and Sorafenib Tosylate in Treating Patients With Transitional Cell Cancer of the Bladder
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: sorafenib tosylate|OTHER: imaging biomarker analysis|OTHER: laboratory biomarker analysis|PROCEDURE: computed tomography|PROCEDURE: neoadjuvant therapy|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head and Torso Rewarming Using a Human Model for Severe Hypothermia
Status: COMPLETED
Conditions: Hypothermia
Interventions: DEVICE: Charcoal Heater (STK Heatpac, Emergco Tech Solutions, B.C.)|OTHER: No heat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of SGI-110 in Patients With IPSS High and Int 2 Myelodysplastic Syndrome, Acute Myeloid Leukemia With 20-30% Marrow Blasts or Chronic Myelomonocytic Leukemia Type 2 Not Responding to Azacitidine or Decitabine After at Least 6 Courses or Relapsing After a Response
Status: COMPLETED
Conditions: MDS
Interventions: DRUG: SGI-110 administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Infarction With Non-Obstructive Coronary Arteries in the Greek Population
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Non-Obstructive Coronary Atherosclerosis|Ischemic Heart Disease|Angina Pectoris|Coronary Microvascular Disease
Interventions: OTHER: MINOCA registry|DIAGNOSTIC_TEST: CCTA Phenotypes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Effect of Breastfeeding Education Given to Mothers Based on Postpartum Awareness Practices on Breast Milk and Cortisol Hormone at the Newborn Circadian Level
Status: NOT_YET_RECRUITING
Conditions: Mother Fetus Relations|Health Behavior
Interventions: BEHAVIORAL: AWARENESS-BASED COGNITIVE THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoperative Hormone Therapy for Postmenopausal Women With ER+ Clinical Stage T2-4 Tumors
Status: COMPLETED
Conditions: Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: DRUG: Exemestane|DRUG: Exemestane and tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Trial of IkT-148009 in Untreated Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: IkT-148009|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime Gel
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DRUG: PRO-165|DRUG: Artelac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT