pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Immunogenicity of Recombinant COVID-19 Vaccine (Sf9 Cell) as a Booster
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Recombinant COVID-19 Vaccine (Sf9 Cell)|BIOLOGICAL: COVID-19 Vaccine (Vero Cell), Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting Reduction of Hypertension After Adrenalectomy for Primary Aldosteronism: a Multicenter Analysis
Status: COMPLETED
Conditions: Primary Aldosteronism Due to Aldosterone Producing Adenoma|Primary Aldosteronism|Primary Aldosteronism Due to Conn Adenoma
Interventions: PROCEDURE: Unilateral adrenalectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Effects of PF00610335 on the QT/QTC Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Pulmonary Disease|Lung Disease|Moxifloxacin
Interventions: DRUG: PF-00610355|DRUG: PF-00610355|DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients
Status: UNKNOWN
Conditions: Head Injury|Intracerebral Hemorrhage|Ischemic Stroke|Subarachnoid Hemorrhage|Brain Tumor|Hydrocephalus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery
Status: TERMINATED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: MINI WELL READY ®|DEVICE: FINE VISION®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Immediate and Delayed Intrauterine Balloon in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis
Status: UNKNOWN
Conditions: Intrauterine Adhesion
Interventions: PROCEDURE: Delayed Intrauterine Balloon therapy|PROCEDURE: immediate Intrauterine Balloon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
Status: NOT_YET_RECRUITING
Conditions: Liver Neoplasms|Primary Liver Cancer|Secondary Liver Cancer|Tumor Liver|Benign Liver Tumor
Interventions: DEVICE: HistoSonics Edison System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Colon Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastrointestinal Cancer|Liver and Intrahepatic Biliary Tract Cancer|Lung Cancer|Metastatic Cancer|Pancreatic Cancer|Rectal Cancer|Thyroid Gland Medullary Carcinoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: radionuclide imaging|PROCEDURE: positron emission tomography|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|DRUG: Cu 64 anti-CEA monoclonal antibody M5A IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Intraventricular Hemorrhage
Interventions: PROCEDURE: Standard 30-60 Seconds Cord Clamping|PROCEDURE: VentFirst 120 Seconds Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Intranasal Oxytocin During Detoxification of Crack Cocaine
Status: UNKNOWN
Conditions: Cocaine Withdrawal|Cocaine Smoking|Cocaine-Related Disorders
Interventions: DRUG: Oxytocin nasal spray|DRUG: placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147)
Status: COMPLETED
Conditions: Urticaria|Chronic Idiopathic Urticaria
Interventions: DRUG: desloratadine|DRUG: desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID Protection After Transplant-Immunosuppression Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Recipients|Liver Transplant Recipients
Interventions: BIOLOGICAL: Pfizer-BioNTech COVID-19 Vaccine 2023-2024|BIOLOGICAL: Moderna COVID-19 Vaccine 2023-2024|DRUG: SOC IS Regimen|DRUG: SOC IS Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Issues for Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Risperidone|DEVICE: hyperbaric oxygen therapy|DRUG: Non specific Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Aphasia Language Therapy
Status: COMPLETED
Conditions: Nonfluent Aphasia|Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation - Cathodal stimulation|DEVICE: Transcranial Direct Current Stimulation - Anodal stimulation|DEVICE: Transcranial Direct Current Stimulation - Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: ReCell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NASH and Type 2 Diabetes: Role of the Receptor Activator of Nuclear Factor-κB (RANK) and Its Ligand (RANKL)
Status: UNKNOWN
Conditions: Diabetes type2|NASH - Nonalcoholic Steatohepatitis|NAFLD
Interventions: BIOLOGICAL: "Collection of additional blood tubes; Biobanking (plasma, liver tissue).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus
Status: COMPLETED
Conditions: Nystagmus
Interventions: DRUG: gabapentin|DRUG: memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocotrienols for Skeletal Muscle Health
Status: WITHDRAWN
Conditions: Dynapenia|Postmenopausal Women
Interventions: DRUG: placebo softgel|DRUG: DeltaGold® Tocotrienol 70%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel, Carboplatin and Radiotherapy as Induction Therapy in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: RADIATION: Radiotherapy|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunostimulatory CpG SD-101 + RT in Recurrent/Progressive Lymphoma After Allogeneic Hematopoietic Cell Transplantation (HCT)
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: DRUG: SD-101|RADIATION: Local Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of BNP in MCS - a 25 Year Follow up Study
Status: RECRUITING
Conditions: Heart Failure|Left Ventricular Assist Device|Prognosis|Durable Mechanical Support Device
Interventions: OTHER: Observation. No intervention per se.|OTHER: 2) Observation and collection and of blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paclitaxel Plus Carboplatin With or Without Topotecan in Treating Patients With Stage IIB, Stage III, or Stage IV Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Peritoneal Metastases
Interventions: OTHER: Routine follow-up|PROCEDURE: Second look DLS|PROCEDURE: Third look DLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Pain, Intractable|Depression
Interventions: DIAGNOSTIC_TEST: fMRI and DTI|BEHAVIORAL: Behavioral questionnaires|BEHAVIORAL: Disease-Specific Patient-Reported Outcomes|BEHAVIORAL: Behavioral tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research on Effect of Traditional Chinese Medicine (TCM) on Immune Reconstitution of HIV/AIDS Patients After Highly Active Antiretroviral Therapy (HAART)
Status: UNKNOWN
Conditions: Acquired Immune Deficiency Syndrome Virus|HIV Infections
Interventions: DRUG: Fuzheng 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Brain Tumor|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Medulloblastoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma
Interventions: DRUG: erlotinib hydrochloride|DRUG: temozolomide|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Argon Plasma Coagulation Vs. Control For Weight Regain After Gastric Surgery
Status: COMPLETED
Conditions: Obesity|Weight Gain
Interventions: PROCEDURE: Argon randomized arm|PROCEDURE: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trunk Rotation And Lateral Flexion Exercises In Stroke Patients
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: chest physiotherapy|OTHER: trunk rotation exercises,deep diaphragmatic also chest physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Evaluation of Melatonin in the Treatment of Pressure Ulcers
Status: NOT_YET_RECRUITING
Conditions: Pressure Ulcer
Interventions: DRUG: Melatonin|DRUG: Hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dengue Controlled Human Infection Model in Dhaka, Bangladesh
Status: ACTIVE_NOT_RECRUITING
Conditions: Dengue
Interventions: BIOLOGICAL: TV005|BIOLOGICAL: rDEN2Δ30-7169 attenuated virus strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Umuryango Ukomera Uri Hamwe - Families Are Strong Together
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Aggressive Behaviour|Parental Maltreatment|Days Spent at the Landfill
Interventions: BEHAVIORAL: Comprehensive family intervention including individual sessions of FORNET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Inclusion of Physical Activity in Secondary School Academic Classes: the ACTIVE CLASS Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity|Adolescents|Cognition|Physical Fitness
Interventions: BEHAVIORAL: Active breaks|BEHAVIORAL: Physically active learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Cocoa Supplementation and Aerobic Exercise on Pressure Parameters
Status: UNKNOWN
Conditions: Sedentary Behavior
Interventions: DIETARY_SUPPLEMENT: Aerobic exercise + Theobroma cocoa (AETC)|DIETARY_SUPPLEMENT: Control Group (CG)|DIETARY_SUPPLEMENT: Aerobic Exercise (AE)|DIETARY_SUPPLEMENT: Theobroma Cocoa (TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Neuromuscular Electrical Stimulation For Quadriceps Muscle Activation Deficits Following Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Neuromuscular Electrical Stimulation (NMES)|OTHER: Standard Rehabilitation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate Carbohydrate Consumption on Metabolic and Obstetric Outcomes in Pregnant Women With Insulin-treated Diabetes- A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Diabetes in Pregnancy
Interventions: OTHER: Nutritional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Broccoli Sprout Extract in Patients With Chronic Kidney Disease With Diabetes Type 2
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease stage4|Diabetes Mellitus, Type 2
Interventions: OTHER: Sulforaphane, administered as Broccoli sprout extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Brain Neoplasm
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder
Status: RECRUITING
Conditions: Methamphetamine Use Disorder|Substance-Related Disorders|Chemically-Induced Disorders|Substance Use Disorders|Stimulant-Use Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: UNITY 3: A Japanese Phase 3 Study of a Daclatasvir/Asunaprevir/BMS-791325 in Subjects With Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Daclatasvir|DRUG: Asunaprevir|DRUG: DCV 3DAA|OTHER: Placebo for DCV 3DAA|OTHER: Placebo for Daclatasvir|OTHER: Placebo for Asunaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol Drinking as a Vital Sign
Status: COMPLETED
Conditions: Unhealthy Drinking|Alcohol Dependence
Interventions: OTHER: Training & Tech Support for Delivery of Alcohol Screening, Brief Intervention, and Referral To Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Triplet Combination of Cytotoxics as First-line Treatment for Metastatic Gastric Cancer
Status: RECRUITING
Conditions: Metastatic Gastric Cancer
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exenatide and Weight Loss for Diabetes Prevention
Status: COMPLETED
Conditions: Pre Diabetes|Insulin Resistance
Interventions: DRUG: Exenatide 5 and 10 mcg 2 times a day|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
Status: RECRUITING
Conditions: Localized Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Cryosurgery|PROCEDURE: High-Intensity Focused Ultrasound Ablation|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Efficacy of Digital Health Technology in the Treatment of Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: BodyPort|OTHER: Noom|OTHER: Conversa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Latency Auditory Evoked Potentials (P300) Outcomes in Patients With Unilateral Cochlear Implants
Status: UNKNOWN
Conditions: Hearing Loss, Sensorineural|Deafness
Interventions: DIAGNOSTIC_TEST: P300 - Auditory long latency potential
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Erythropoietin in Premature Infants to Prevent Encephalopathy
Status: TERMINATED
Conditions: Premature Infant
Interventions: DRUG: Epo|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depodur vs Fentanyl Infusion for Post-C/S Analgesia
Status: WITHDRAWN
Conditions: Analgesia
Interventions: DRUG: Depodur|DRUG: Depodur|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Electrolyte Maintenance Solution Required in Low-Risk Children With Gastroenteritis?
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: OTHER: ½ strength apple juice|OTHER: Pediatric Electrolyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Non-vItamiN K antaGonist oraL Anticoagulants for intermEdiate Stroke Risk in Patients With Atrial Fibrillation (SINGLE-AF)
Status: RECRUITING
Conditions: Atrial Fibrillation Patients With Intermediate Stroke Risk
Interventions: DRUG: Anticoagulation group(Apixaban group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB
Status: RECRUITING
Conditions: Efficacy|Safety|Pharmacokinetics
Interventions: DRUG: Hepenofovir Fumarate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Obstructive Sleep Apnea (OSA) Using Portable Sleep Testing (PST) Devices on an Inpatient Stroke Unit
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Portable sleep apnea screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A First-in-Human Study to Assess the Safety and Tolerability of PDNO
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: PDNO|DRUG: Sodium chloride (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microcurrent Therapy in the Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis,Knee
Interventions: DEVICE: Microcurrent therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a New Polypectomy Snare for Cold-polypectomy for Small Colorectal Polyps
Status: COMPLETED
Conditions: Polyp of Large Intestine|Colonic Polyps|Colon Nos Polypectomy Tubular Adenoma|Complications|Bleeding
Interventions: DEVICE: Exacto™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resilience-Building Nursing Intervention for Elderly Well-being
Status: NOT_YET_RECRUITING
Conditions: Psychological Well-being in Older Adults|Resilience Building Intervention|Community Dwelling Older Adults
Interventions: OTHER: Resilience-Enhancing Nursing Suppor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EFFECTS OF SHOCK WAVE THERAPY IN WOMEN WITH PAIN IN TRAPÉZIO MUSCLE
Status: COMPLETED
Conditions: Pain|Muscle Tonus
Interventions: DEVICE: Experimental - Shock wave therapy|DEVICE: Placebo - Shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transforming Hypertension Treatment in Nigeria Using a Type II Hybrid, Interrupted Time Series Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: OTHER: Evidence-based fixed-dose combination protocol based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of a New Software ENgine for the Assessment & Optimization of Drug and Non-drug Therapy in Older peRsons
Status: COMPLETED
Conditions: Adverse Drug Reactions
Interventions: OTHER: SENATOR software generated pharmacotherapy advice report.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Prospective Multicenter Randomized Study of Endoscopic Treatment of Stenosis in Crohn´s Disease
Status: UNKNOWN
Conditions: Stenosis|Crohn's Disease|Chronic Inflammation
Interventions: DEVICE: Placing a self-expanding metallic stent|DEVICE: A balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for Brachytherapy
Status: COMPLETED
Conditions: Prostate Cancer|Erectile Dysfunction|Lower Urinary Tract Symptoms
Interventions: DRUG: administration of a LHRH agonist and Bicalutamide|DRUG: administration of Bicalutamide, Dutasteride and Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN)
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage (SAH)|Left Ventricular Dysfunction|Stress Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Global Longitudinal Strain measure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Sinusitis|Nasal Polyps|Asthma
Interventions: DRUG: Montelukast|DRUG: mometasone furoate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered Therapy for Alcohol Misuse: Investigating Patient Preference for Self-guided or Guided Treatment
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Guidance|BEHAVIORAL: ICBT for alcohol misuse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Anterior Lumbar Interbody Fusion (ALIF) in Spinal Deformity
Status: COMPLETED
Conditions: Spinal Deformity
Interventions: DEVICE: Tantalum cage from Zimmer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Utilizing Patient-Reported Outcomes to Evaluate the Safety and Efficacy of Lorecivivint (SM04690) for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis (STRIDES)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Lorecivivint|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine/Rosuvastatin
Status: COMPLETED
Conditions: Dyslipidemia With Hypertension
Interventions: DRUG: Group I (Telmisartan 80 mg, Amlodipine 10 mg, Rosuvastatin 20 mg)|DRUG: Group II (Telmisartan 80 mg, Amodipine 10 mg, Rosuvastatin placebo)|DRUG: Group III (Telmisartan 80 mg, Amlodipine placebo, Rosuvastatin 20 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Blood and Tissue Samples From Patients Receiving Androgen Deprivation for Newly Diagnosed Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: antiandrogen therapy|DRUG: releasing hormone agonist therapy|GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: comparative genomic hybridization|GENETIC: gene expression analysis|OTHER: laboratory biomarker analysis|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Testing the Neuroscience of Guided Learning in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Standard Learning|BEHAVIORAL: Guided Learning: Instructed statistics|BEHAVIORAL: Guided Learning: Changing statistics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neurological Monitoring in Patients Switching From Dolutegravir Based Regimen to Bictegravir Based Regimen
Status: UNKNOWN
Conditions: HIV-1-infection
Interventions: DRUG: Bictegravir/emtricitabine/tenofovir alafenamide|DRUG: Dolutegravir/lamivudine/abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior
Status: COMPLETED
Conditions: Obesity|Type II Diabetes|Cardiovascular Disease|Health Behavior
Interventions: OTHER: STRIDES|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Clofarabine in Pediatric Acute Myelogenous Leukemia (AML) Patients
Status: COMPLETED
Conditions: Leukemia, Myelocytic, Acute, Pediatric
Interventions: DRUG: clofarabine (IV formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PI-targeted PNE+MI Compared to BIOMEDICAL Education in BCS
Status: RECRUITING
Conditions: Breast Neoplasms|Survivorship|Pain, Chronic
Interventions: BEHAVIORAL: Pain Neuroscience Education (PNE)|BEHAVIORAL: Motivational Interviewing (MI)|BEHAVIORAL: Biomedically-focused education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing CNS-Active Medications to Prevent Falls and Injuries in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|Accidental Fall
Interventions: BEHAVIORAL: STOP Falls Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of an Encapsulated Cell Technology (ECT) Implant for Patients With Atrophic Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: NT-501 implant|DRUG: NT-501 implant|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalization of CM Injection Protocols in Coronary Computed Tomographic Angiography
Status: COMPLETED
Conditions: Coronary Artery Calcification|Cardiac Disease
Interventions: OTHER: Contrast media administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Extension for Patients Coming From the Dosing Flexibility Study in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Certain Prevail Implants Used for the Preservation of Crestal Bone in Short Fixed Bridge Cases.
Status: COMPLETED
Conditions: Partial Edentulism|Tooth Disease
Interventions: DEVICE: Dental implant Osseotite Prevail|DEVICE: Dental implant Osseotite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ginkgo Biloba to Improve Short-Term Memory Losses Associated With Electroconvulsive Therapy (ECT)
Status: TERMINATED
Conditions: Memory, Short-Term
Interventions: DRUG: ginkgo biloba|OTHER: matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Hand Hygiene Activities on the Prevention of Intestinal Parasitic Infections and Anaemia Among School Children
Status: COMPLETED
Conditions: Intestinal Parasitic Infections|Anaemia
Interventions: BEHAVIORAL: Hand washing with soap and hand finger nail clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Aprepitant|DRUG: Scopolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplementation of of DHA, Vitamin D3 and Uridine in Children
Status: COMPLETED
Conditions: Children
Interventions: DIETARY_SUPPLEMENT: DDU-supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Performance and Safety Assessment of T4020 in Managing Corneal Epithelial Defect Following Epi-off Accelerated Crosslinking
Status: COMPLETED
Conditions: Keratoconus
Interventions: DEVICE: T4020|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study)
Status: COMPLETED
Conditions: Partial Seizures
Interventions: DRUG: Zonisamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar Keratoplasty
Status: COMPLETED
Conditions: Corneal Ulcer|Leukoma
Interventions: DEVICE: Collagen-MPC cornea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile
Status: COMPLETED
Conditions: Metabolism Disorder|Insulin Sensitivity|Obesity, Pediatric
Interventions: BEHAVIORAL: High Intensity Training (HIT) + Resistance Training (RT)|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer
Status: NOT_YET_RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: metformin|RADIATION: Radioactive iodine (I-131)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Oral Mucositis Using Platelet Rich Fibrin TREATMENT OF ORAL MUCOSITIS USING PRF
Status: COMPLETED
Conditions: Graft Vs Host Disease|Oral Mucositis (Ulcerative)|Mesenchymal Stem Cells
Interventions: DEVICE: TREATMENT OF ORAL MUCOSITIS USING PLATELET-RICH-FIBRIN (PRF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Photodynamic Therapy Versus Argon Plasma Coagulation for Lung Cancer With Endobronchial Obstruction
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Photodynamic Therapy|PROCEDURE: Argon Plasma Coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects Of Alliance Therapy In Modulation Of Pain And Disability In Subjects With Knee Osteoarthritis
Status: COMPLETED
Conditions: Arthritis|Knee Osteoarthritis
Interventions: OTHER: Kinesio Taping and therapeutic alliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/Action
Status: COMPLETED
Conditions: Insulin Sensitivity|Multiple Mitochondrial Dysfunctions Syndrome
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions
Status: RECRUITING
Conditions: Multiple Chronic Conditions|Adverse Event
Interventions: BEHAVIORAL: ePRO Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Macular Degeneration
Interventions: DRUG: Intravitreal Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Premeal Protein-bar on Glycemic Control in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Patients With Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Premeal protein enriched bar|BEHAVIORAL: Dietary modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mental Health Symptom Monitoring Utilizing the Cogito Behavioral Analytic Platform
Status: COMPLETED
Conditions: Mobile Applications|Cell Phone Use|Mental Health Issue|Acceptability of Health Care|Feasibility
Interventions: BEHAVIORAL: Cogito Companion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress
Status: RECRUITING
Conditions: Li-Fraumeni Syndrome|TP53 Gene Mutation|Hereditary Cancer Syndrome|Clonal Hematopoiesis|Mosaicism
Interventions: GENETIC: Data and Specimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regenerative Treatment of Traumatized Immature Permanent Incisors With Pulp Necrosis
Status: UNKNOWN
Conditions: Regenerative Endodontics in Traumatized Immature Teeth
Interventions: DRUG: Calcium hydroxide (Calacept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Study of Expectancy on Acupuncture Treatment Outcomes in Knee OA
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amrubicin and Irinotecan in Treating Patients With Recurrent or Relapsed Extensive Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: amrubicin hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Methoxy Polyethylene Glycol-epoetin Beta (Mircera) in Participants With Chronic Kidney Disease (PRIMAVERA)
Status: COMPLETED
Conditions: Kidney Disease, Chronic
Interventions: DRUG: Methoxy polyethylene glycol-epoetin beta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Swallowing Pressure Profiles in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Videofluoroscopic swallow study|PROCEDURE: pharyngeal High Resolution Manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study To Evaluate The Efficacy And Safety Of A Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR).
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: GW685698X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Tolerability of Exenatide in Adolescent Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide - Exenatide - Placebo|DRUG: Exenatide - Placebo - Exenatide|DRUG: Placebo - Exenatide - Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of Natural Eggshell Membrane (NEM) for the Treatment of Joint & Connective Tissue Disorders
Status: COMPLETED
Conditions: Osteoarthritis|Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: NEM Formulation X|DIETARY_SUPPLEMENT: NEM Formulation Y
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Intravenous Daclizumab|DRUG: Intravenous Infliximab|OTHER: Observation|DRUG: Oral Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Efavirenz|DRUG: Stavudine|DRUG: Didanosine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Everolimus (RAD001), and Lapatinib as Neoadjuvant Chemotherapy Regimes for Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: epirubicin - cyclophosphamide / docetaxel|DRUG: epirubicin - cyclophosphamide / docetaxel + bevacizumab|DRUG: paclitaxel|DRUG: paclitaxel + everolimus (RAD001)|DRUG: epirubicin - cyclophosphamide / docetaxel + trastuzumab|DRUG: epirubicin - cyclophosphamide / docetaxel + lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19
Status: COMPLETED
Conditions: Cancer|COVID
Interventions: DIAGNOSTIC_TEST: Nasopharyngeal and throat/oropharyngeal swabs analyses by RT-PCR and ddPCR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect on Markers of Cardiovascular, Reproductive and Cancer Risk From Firefighting Training
Status: RECRUITING
Conditions: Reactive Hyperemia|Micro RNA|Heart Rate Variability|DNA Strand Breaks|Oxidative Stress|Heat Stress
Interventions: OTHER: Firefighting training exercises with no fire|OTHER: Firefighting training exercises under wood fire|OTHER: Firefighting training exercises under gas fire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of DCB Therapy for de Novo Lesions Under the Guidance of QFR in CHD Patients (UNIQUE-DCB-I Study )
Status: NOT_YET_RECRUITING
Conditions: Coronary Heart Disease
Interventions: DEVICE: drug coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Pilot Study Evaluating the Immunogenicity of an Innovative Pneumococcal Vaccination Strategy in Splenectomized Adults
Status: COMPLETED
Conditions: Splenectomized Patients
Interventions: BIOLOGICAL: Prime-boost pneumococcal immunization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preventing Neck & Back Pain in Teleworking Office Workers: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Neck Pain|Low Back Pain|Back Pain
Interventions: OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin and Attachment-related Interpretation Bias
Status: COMPLETED
Conditions: Trust
Interventions: DRUG: Oxytocin|DRUG: Placebo|OTHER: Secure CBM training|OTHER: Neutral CBM training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Supplementation During Caloric Restriction on Intestinal Calcium Absorption
Status: COMPLETED
Conditions: Weight Loss|Vitamin D or Placebo
Interventions: BEHAVIORAL: Weight Loss|DIETARY_SUPPLEMENT: Vitamin D 2500 IU|BEHAVIORAL: Weight Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye Syndromes|Cataract
Interventions: DRUG: Sodium Carboxymethylcellulose|DRUG: Levofloxacin|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACEMg for Hearing Preservation and Tinnitus Mitigation
Status: NOT_YET_RECRUITING
Conditions: Sensorineural Hearing Loss|Tinnitus|SNHL|Inner Ear Hearing Loss
Interventions: DIETARY_SUPPLEMENT: ACEMg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION