pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Telerehabilitation-Based Structured Exercise Program in Video Game-Addicted Adults
Status: COMPLETED
Conditions: Video Game Addiction
Interventions: OTHER: Brochure-Based Exercise Program|OTHER: Telerehabilitation-Based Structured Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pembrolizumab (Keytruda®) on Biomarkers in Early Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Triple Negative Breast Cancer|Hormone Receptor Negative Neoplasm
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: First in Human Study of Winsor Laser Catheter: A Prospective Registry to Evaluate The Safety and Performance of the Winsor Laser Catheter in the Treatment of In-Stent Restenosis
Status: WITHDRAWN
Conditions: Femoropopliteal In-Stent Restenosis
Interventions: DEVICE: Winsor Laser Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fructose and Lactose Intolerance and Malabsorption in Functional Gastrointestinal Disorders
Status: UNKNOWN
Conditions: Functional Gastrointestinal Disorders|Lactose Intolerance|Fructose Intolerance
Interventions: OTHER: no intervention: observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment for Aerobic Vaginitis by Using Bofukang Vaginal Suppository
Status: RECRUITING
Conditions: Vaginitis
Interventions: DRUG: Experimental: Baofukang Suppository 7 days|DRUG: Experimental: Baofukang Suppository 14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
Status: UNKNOWN
Conditions: Lower Extremity Fracture
Interventions: DRUG: Atropine|DRUG: Glycopyrrolate|DRUG: Normal Saline Flush, 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SP16 SERPIN-like Peptide Administration in Healthy Individuals
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: SP16|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Verses Propofol for Paediatric MRI Brain
Status: COMPLETED
Conditions: Brain Diseases
Interventions: DRUG: Dexmedetomidine|DRUG: propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of a Skin Test for the Na-ASP-2 Hookworm Antigen
Status: COMPLETED
Conditions: Hookworm Infection|Allergy
Interventions: BIOLOGICAL: Na-ASP-2 Skin Test Reagent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Traditional (Traditional Chemoembolization) TACE Versus Microsphere TACE
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Selective TACE via microsphere loaded with Doxorubicin|PROCEDURE: Selective traditional TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Squatting Position on Constipation Severity and Defecation Problems
Status: COMPLETED
Conditions: Constipation|Postoperative Care|Nursing Care
Interventions: OTHER: Squatting position by footstool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Hepaguard® in Adults With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Phyllanthus urinaria|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic vs. Open Distal Gastrectomy After Neoadjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasm
Interventions: PROCEDURE: Laparoscopic versus open distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Status: SUSPENDED
Conditions: Dental Caries
Interventions: PROCEDURE: WMP of fluoride varnish|PROCEDURE: TWLP of fluoride varnish|BEHAVIORAL: DHP (educational intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The UniVenture Program
Status: UNKNOWN
Conditions: Anxiety Sensitivity|Hopelessness|Sensation Seeking|Impulsivity
Interventions: BEHAVIORAL: UniVenture Hopelessness manual|BEHAVIORAL: UniVenture Anxiety Sensitivity manual|BEHAVIORAL: UniVenture Sensation Seeking manual|BEHAVIORAL: UniVenture Impulsivity manual|BEHAVIORAL: Service as usual provided by the University
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on Efficacy and Tolerability of Vorinostat in Patients With Advanced, Metastatic Soft Tissue Sarcoma (STS)
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Solution-focused Group Therapy for Pain Management in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Pain Management|Life Quality|Spinal Cord Injuries
Interventions: BEHAVIORAL: solution-focused group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Cetuximab for Unresectable or Metastatic Esophageal and Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|Neoplasm Metastasis
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Tardive Dyskinesia|Insulin Resistance|Obesity
Interventions: DRUG: Panax Ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of CFZ533 in Patients With Sjögren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: CFZ533 (iscalimab)|OTHER: CFZ533 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fit For Delivery: A Study of the Effect of Exercise Sessions and Nutritional Counselling on Pregnancy Outcome
Status: COMPLETED
Conditions: Pregnancy|Obesity|Diabetes
Interventions: BEHAVIORAL: Nutritional counseling + exercise groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's)
Status: COMPLETED
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: OTHER: procalcitonin-guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Deconstructive Psychotherapy Versus Brief Intervention and Contact for Suicidal Adolescents and Young Adults
Status: RECRUITING
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Dynamic Deconstructive Psychotherapy (DDP)|BEHAVIORAL: Brief Intervention and Contact (BIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Multicenter Study to Assess the Efficacy of Bilateral Pallidal Stimulation in Patients With Medically Refractory Primary Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DEVICE: Deep brain stimulation (DBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota: Immunity, Recovery and Metabolic Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo Comparator|DIETARY_SUPPLEMENT: Whey protein hydrolysate milk product|DIETARY_SUPPLEMENT: Postbiotic and whey protein hydrolysate milk product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: WITHDRAWN
Conditions: Stage II Fallopian Tube Cancer AJCC v8|Stage II Ovarian Cancer AJCC v8|Stage II Primary Peritoneal Cancer AJCC v8|Stage IIA Fallopian Tube Cancer AJCC v8|Stage IIA Ovarian Cancer AJCC v8|Stage IIA Primary Peritoneal Cancer AJCC v8|Stage IIB Fallopian Tube Cancer AJCC v8|Stage IIB Ovarian Cancer AJCC v8|Stage IIB Primary Peritoneal Cancer AJCC v8|Stage III Fallopian Tube Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Primary Peritoneal Cancer AJCC v8|Stage IIIA Fallopian Tube Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA Primary Peritoneal Cancer AJCC v8|Stage IIIA1 Fallopian Tube Cancer AJCC v8|Stage IIIA1 Ovarian Cancer AJCC v8|Stage IIIA2 Fallopian Tube Cancer AJCC v8|Stage IIIA2 Ovarian Cancer AJCC v8|Stage IIIB Fallopian Tube Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIB Primary Peritoneal Cancer AJCC v8|Stage IIIC Fallopian Tube Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Stage IVA Fallopian Tube Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Primary Peritoneal Cancer AJCC v8|Stage IVB Fallopian Tube Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Primary Peritoneal Cancer AJCC v8
Interventions: BIOLOGICAL: Alpha-type-1 Polarized Dendritic Cells|BIOLOGICAL: Autologous Natural Killer Cell-like CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Safety And Pharmacokinetics Of CE-326,597 In Patients With Asymptomatic Gallstones
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: CE-326,597|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers|Tauopathies|Alzheimer Disease
Interventions: DRUG: APNmAb005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Steroids in Controlled Glaucoma
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DRUG: Nasal steroid Beclomethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Adult Solid Neoplasm|Recurrent Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Buparlisib|DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
Status: COMPLETED
Conditions: Brain Cancer
Interventions: DRUG: Nivolumab|DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nateglinide vs Acarbose on Postprandial Glucose Fluctuation, Dyslipidemia, and Inflammatory Factors
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Nateglinide 120 mg|DRUG: Acarbose 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tupler's Technique on the Management of Diastasis Rectus Abdominis.
Status: RECRUITING
Conditions: Diastasis Rectus Abdominis
Interventions: OTHER: Tupler's Technique|OTHER: Traditional Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled BUDESONIDE/FORMOTEROL in Bronchiolitis Obliterans Following Stem Cell Transplantation
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Allogeneic Stem Cell Transplantation
Interventions: DRUG: Budesonide/formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care
Status: COMPLETED
Conditions: Risky Health Behavior|Drinking, Alcohol|Alcohol Use Disorder|Drinking, Binge|Drinking Excessive
Interventions: OTHER: Practice Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accurate Prostate Cancer Following Using Low-Field MRI (Low-PRISM)
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Siemens Magnetom Free.Max 0.55T (Siemens Healthineers, Erlangen, Germany).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder
Status: RECRUITING
Conditions: RUNX1 Familial Platelet Disorder
Interventions: DRUG: G-CSF (filgrastim or biosimilar)|PROCEDURE: Apheresis|DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chronic Hepatitis C Virus Related Thrombocytopenia to Evaluate the Effects of E5501
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DRUG: Avatrombopag|DRUG: Placebo|DRUG: Pegylated interferon (PEG-IFN)|DRUG: Telaprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: C-MAC Videolaryngoscopy Versus Direct Laryngoscopy for Percutaneous Tracheostomy
Status: RECRUITING
Conditions: Intubated Patients|Percutaneous Tracheostomy
Interventions: DEVICE: C-MAC videolayngoscopy technique|DEVICE: Laryngoscopy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ODM-103 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ODM103|DRUG: Placebo|DRUG: Entacapone|DRUG: Levodopa/carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: To Compare the Efficacy of Carbepenem Versus Carbepenem Plus GM-CSF in Difficult To Treat Spontaneous Bacterial Peritonitis
Status: COMPLETED
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Carbepenem|DRUG: Albumin|DRUG: GMCSF (of Granulocyte-Monocyte Colony-Stimulating Factor) .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|Cirrhosis|Portal Hypertension
Interventions: COMBINATION_PRODUCT: Methacetin Breath Test|DRUG: Emricasan|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Paraspinal Muscle Degeneration, Bone Mass and Clinical Outcomes in Patients With Lumbar Degenerative Diseases
Status: UNKNOWN
Conditions: Degenerative Lumbar Spinal Stenosis|Degenerative Scoliosis
Interventions: OTHER: Pre-existing degenerative factors of paraspinal muscles and bone mass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT to Describe the Effects of Colon Delivered Acetate, Propionate and Butyrate on Satiety and Glucose Homeostasis
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Inulin acetate ester|DIETARY_SUPPLEMENT: Inulin propionate ester|DIETARY_SUPPLEMENT: Inulin butyrate ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Response Effect of Atomoxetine to the Acute Effects of Alcohol
Status: TERMINATED
Conditions: Alcohol Craving|Mood Changes
Interventions: DRUG: Atomoxetine, Strattera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients
Status: NOT_YET_RECRUITING
Conditions: Ventilator Weaning
Interventions: PROCEDURE: Systematic and early intensive instrumental respiratory physiotherapy for patients undergoing difficult ventilatory weaning|PROCEDURE: Protocolized standard-of-care respiratory physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Molnupiravir (MK-4482) in Participants With Moderate Hepatic Impairment (MK-4482-016)
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Molnupiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously Implanted
Status: ENROLLING_BY_INVITATION
Conditions: Hip Replacement
Interventions: DEVICE: REDAPT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remifentanil-dexmedetomidine Anesthesia With a Caudal for Elective Surgery. (Remi-dex)
Status: WITHDRAWN
Conditions: Anesthesia
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Holistic Assessment of Tulsa Children's Health
Status: COMPLETED
Conditions: Pregnancy
Interventions: BEHAVIORAL: Babies and Moms connected through Love, Openness, and Opportunity (BLOOM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dietary Fat Cooking Blend on Energy Expenditure in Children
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: DIETARY_SUPPLEMENT: Melt (test oil)|DIETARY_SUPPLEMENT: Corn oil (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Weight-Loss Program in Helping Obese Black Women Lose Weight
Status: UNKNOWN
Conditions: Breast Cancer|Obesity|Weight Changes
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|BEHAVIORAL: telephone-based intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: support group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Comparison of Dry Needling and Dry Cupping in Positional Fault of Pelvis
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain|Quadratus Lumborum Syndrome|Positional Fault of Pelvis|Myofascial Trigger Point in Quadratus Lumborum
Interventions: OTHER: Dry needling|OTHER: Dry cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Deuterium Metabolic MRI and [18F]FDG PET for Assessment of Treatment Response Following Radioembolization
Status: RECRUITING
Conditions: Fluorodeoxyglucose F18|Phosphoric Monoester Hydrolases|Phosphoric Diester Hydrolases
Interventions: DIAGNOSTIC_TEST: Deuterium Glucose Metabolic Imaging with MRI spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of ZX-7101A Tablets in Adults With Uncomplicated Influenza
Status: RECRUITING
Conditions: Influenza, Human
Interventions: DRUG: ZX-7101A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation Based on Driving Pressure in Lateral Position
Status: SUSPENDED
Conditions: Fracture of Hip|Osteoarthritis, Hip|Congenital Hip Deformity
Interventions: PROCEDURE: routine lung protective, conventional mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.
Status: COMPLETED
Conditions: Acute Heart Failure
Interventions: DRUG: Furosemide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Metformin (1000 mg daily), Pioglitazone (30 mg daily), Acetyl-L-carnitine (3 gm daily)|DRUG: Metformin, pioglitazone and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on Refinement of Early Stage Lung Cancer Adjuvant Therapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery of Subclinical Cortisol Secreting Adrenal Incidentalomas
Status: COMPLETED
Conditions: Adrenal Incidentalomas
Interventions: PROCEDURE: Laparoscopic surgical removal of the adrenal tumor|DRUG: Standardized medical treatment of hypertension by SAHR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygenation Instability and Maturation of Control of Breathing in Premature Infants
Status: COMPLETED
Conditions: Infant,Premature
Interventions: OTHER: Assessment of oxygenation instability|OTHER: Determination of mechanisms of hypoxemia episodes|OTHER: Assessment of respiratory instability|OTHER: apneic threshold of CO2|OTHER: Assessment of peripheral chemoreceptor function|OTHER: Assessment of central chemo-receptor function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-edotreotide PRRT|DRUG: Everolimus|OTHER: Amino-Acid Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Digitalized Cognitive-behavioral Intervention for Childhood Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Digitalized cognitive-behavioral intervention for anxiety|BEHAVIORAL: Psychoeducation about anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: atazanavir/cobicistat|DRUG: darunavir/ritonavir dosage #1|DRUG: darunavir/ritonavir dosage #2|DRUG: darunavir/ritonavir dosage #3|DRUG: elvitegravir/cobicistat|DRUG: dolutegravir|DRUG: tenofovir alafenamide fumarate (TAF)|DRUG: TAF w/cobicistat|DRUG: TAF w/cobicistat or ritonavir|DRUG: efavirenz|DRUG: darunavir/cobicistat|DRUG: lopinavir/ritonavir dosage #1|DRUG: atazanavir/ritonavir/tenofovir dosage #1|DRUG: rifampicin|DRUG: ethambutol|DRUG: isoniazid|DRUG: pyrazinamide|DRUG: kanamycin|DRUG: amikacin|DRUG: capreomycin|DRUG: moxifloxacin|DRUG: levoflaxacin|DRUG: ofloxacin|DRUG: ethionamide/prothionamide|DRUG: terizidone/cycloserine|DRUG: para-aminosalicylic acid (PAS)|DRUG: high dose INH|DRUG: bedaquiline|DRUG: clofazamine|DRUG: delamanid|DRUG: linezolid|DRUG: pretomanid|DRUG: ethinyl estradiol|DRUG: etonogestrel implant|DRUG: nevirapine|DRUG: amprenavir|DRUG: abacavir|DRUG: lopinavir/ritonavir dosage #2|DRUG: indinavir/ritonavir dosage #1|DRUG: fosamprenavir/ritonavir|DRUG: lopinavir/ritonavir dosage #3|DRUG: atazanavir/ritonavir dosage #1|DRUG: didanosine delayed release (Videx® EC)|DRUG: emtricitabine|DRUG: tenofovir|DRUG: nelfinavir dosage #1|DRUG: tipranavir/ritonavir|DRUG: lopinavir/ritonavir dosage #4|DRUG: raltegravir|DRUG: etravirine|DRUG: maraviroc|DRUG: atazanavir/ritonavir dosage #2|DRUG: tenofovir/atazanavir/ritonavir dosage #2|DRUG: nelfinavir dosage #2|DRUG: indinavir/ritonavir dosage #2|DRUG: rilpivirine|DRUG: darunavir/ritonavir dosage #4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Clinical Performances of Air-Q SP 3G and i-Gel
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: i-gel Supraglottic device insertion|DEVICE: Air-Q SP 3G Supraglottic device insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Efficacy of Mango Polyphenols in Lean and Obese
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Mango|DIETARY_SUPPLEMENT: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery
Status: TERMINATED
Conditions: Intraocular Lens Replacement|Intraoperative Floppy Iris Syndrome
Interventions: DRUG: Part 1 OMS302|DRUG: Part 2 OMS302|DRUG: Part 2 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients.
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: lemongrass essential oil gel|DRUG: Placebo|PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Relative Effectiveness of Two Feeding Interventions for the Treatment of Moderate Acute Malnutrition
Status: COMPLETED
Conditions: Child Nutrition Disorders
Interventions: DIETARY_SUPPLEMENT: Fortified blended foods, Corn Soya Bean Flour (CSB) with oil.|DIETARY_SUPPLEMENT: RUSF (ready-to-use supplementary foods) Supplementary Plumpy®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fat Supplementation on Dumping Syndrome Related Symptoms After Gastric Surgery
Status: RECRUITING
Conditions: Dumping Syndrome|Gastric Surgery
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: Resource Energy|DIETARY_SUPPLEMENT: Dietary Supplement: Calogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation|Primary Focal Segmental Glomerulosclerosis (FSGS)
Interventions: DRUG: Bleselumab|DRUG: Basiliximab|DRUG: Mycophenolate Mofetil (MMF)|DRUG: Tacrolimus Capsules|DRUG: Methylprednisone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Status: RECRUITING
Conditions: Pituitary Neoplasm
Interventions: OTHER: ESC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pharmacological Activation of Brown Adipose Tissue Metabolism
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Mirbetriq (Mirabegron)|OTHER: cold exposure|RADIATION: injection of 18FDG|RADIATION: injection of 11C-acetate|RADIATION: [3-3H]-glucose|OTHER: [U-13C]-palmitate|OTHER: 2H-Glycerol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer
Status: TERMINATED
Conditions: Chemotherapy|Breast Cancer, Metastatic
Interventions: DRUG: Cyclophosphamide, Capecitabine, Methotrexate, Celecoxib, Pamidronate (or Zoledronate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)
Status: RECRUITING
Conditions: HPV-positive Oropharyngeal Squamous Cell Carcinoma
Interventions: PROCEDURE: Robotic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Plastic Reconstruction of Soft Tissue Dehiscences After the Removal of Localized Gingival Enlargements
Status: RECRUITING
Conditions: Localized Gingival Enlargement|Epulides|Recurrence|Periodontal; Lesion
Interventions: PROCEDURE: Surgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: OTHER: CHX0.12+CPC0.05 oral rinse (PerioAidActive Control)|OTHER: placebo rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Etoposide+Cytarabine+PEG-rhG-CSF for Hematopoietic Stem Cell Mobilization in Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Hematological Malignancy
Interventions: DRUG: Etoposide|DRUG: Cytarabine|DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orbicularis Oris Z-plasty Modification of Modified Millard Technique and the Esthetic Outcome of Cleft Lip Repair
Status: ENROLLING_BY_INVITATION
Conditions: Cleft Lip
Interventions: PROCEDURE: orbicularis oris muscle Z- plasty modification of modified millard technique|PROCEDURE: modified millard technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine With or Without Co-administration of Cervarix and Boostrix in Female Adolescents and Young Adults
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612|BIOLOGICAL: Cervarix®|BIOLOGICAL: Boostrix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neural Effects of Green Tea Extract on Dorsolateral Prefrontal Cortex
Status: COMPLETED
Conditions: Exploratory Behavior
Interventions: DIETARY_SUPPLEMENT: Single intragastric instillation of 250 ml green tea extract|DIETARY_SUPPLEMENT: Single intragastric instillation of 500 ml green tea extract|DIETARY_SUPPLEMENT: Single intragastric instillation of 250 ml control solution|DIETARY_SUPPLEMENT: Single intragastric instillation of 500 ml control solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics of Recombinant Factor XIII in Healthy Volunteers
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FXIII Deficiency|Healthy
Interventions: DRUG: catridecacog|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Inetetamab|DRUG: Rapamycin|DRUG: Pyrotinib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Next-generation Sequencing Panel for Identification of Germline Mutations in Early Onset Cancers With Sporadic or Hereditary Presentation
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Colorectal Cancer|Pediatric Cancers|Multiple Primary Malignant Tumours
Interventions: GENETIC: Genetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Minimally Invasive Surgery in Treating Patients With Spinal Tumors
Status: TERMINATED
Conditions: Adult Spinal Cord Neoplasm|Recurrent Adult Spinal Cord Neoplasm|Spinal Bone Metastases|Spinal Cord Metastases
Interventions: PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic conventional surgery|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stand Up Kansas: An Intervention to Reduce Sedentary Behavior in the Home Work Environment
Status: UNKNOWN
Conditions: Sedentary Behavior|Behavior, Health|Cholesterolemia|Obesity|Stress|Hypertension|Fatigue|Glucose, High Blood|Mood
Interventions: DEVICE: Desk Only|BEHAVIORAL: Program Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Cutting Blades for Total Knee Arthroplasty on Implant Migration
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: New saw blade|PROCEDURE: Reprocessed saw blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Activating and Identifying Neural Responses to Social Rejection: a Combined tDCS and fMRI Study
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Re³ (Re-Cube: Retain Remicade® Response)(Study P04249AM3)
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Infliximab Increased Frequency|DRUG: Infliximab Increased Dose|DRUG: Infliximab Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Echocardiographic Techniques in Diagnosis of Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Disease
Interventions: PROCEDURE: Myocardial contrast echocardiography|PROCEDURE: Stress echocardiography with dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Urodynamic Testing: Can we Improve Patient Experience?
Status: COMPLETED
Conditions: Urinary Incontinence|Urinary Bladder, Overactive|Lower Urinary Tract Symptoms
Interventions: OTHER: Preprocedure Telephone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Platelet Activation in Delayed Cerebral Ischemia Secondary to Aneurysmal Subarachnoid Hemorrhage
Status: RECRUITING
Conditions: Aneuvrysmal Subarachnoid Hemorrhage|Delayed Cerebral Ischemia|Endotheliopathy|Platelets Kinetic
Interventions: OTHER: blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Fabric Mattress Cover for Patient Comfort
Status: COMPLETED
Conditions: Patient Comfort
Interventions: OTHER: Mattress protector for days 1 and 2|OTHER: Mattress protector for days 3 and 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Persistence of Varicella Immunity in Hospital Employees Receiving Varicella Vaccine
Status: WITHDRAWN
Conditions: Persistence of Varicella Immunity
Interventions: BIOLOGICAL: Varicella vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis|Psoriatic Arthritis
Interventions: DIAGNOSTIC_TEST: serum raftlin-1 protein levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Apples on cardioVascular Risk And Gut Health
Status: COMPLETED
Conditions: Mild Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: whole apples (WA)|DIETARY_SUPPLEMENT: apple juice (AJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria
Status: COMPLETED
Conditions: EPP|XLP
Interventions: DRUG: Placebo|DRUG: MT-7117 Low Dose|DRUG: MT-7117 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
Interventions: DRUG: SAR408701 (Tusamitamab ravtansine)|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Moderate to Severe Cancer Pain
Status: TERMINATED
Conditions: Pain|Cancer
Interventions: DRUG: Fentanyl Transdermal Matrix Patch ZR-02-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial in Cardiac Resynchronization Therapy (CRT): Right Ventricular Apex Versus High Posterior Septum
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DEVICE: CRT in heart failure; Right ventricular apex v.s. high posterior septum|DEVICE: CRT in heart failure; Right ventricular apex v.s. high posterior septum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breast Feeding Counseling and Video Demonstration on Exclusive Breast Feeding Rates at 6 Weeks
Status: COMPLETED
Conditions: Exclusive Breast Feeding
Interventions: BEHAVIORAL: video demonstration|BEHAVIORAL: counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Near to Infrared (NIR) Light Neuroprotection in Glaucomatous Optic Neuropathy
Status: UNKNOWN
Conditions: Open Angle Glaucoma
Interventions: DEVICE: Near to infrared light retinal stimulation|DEVICE: Green light stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clobetasol Topical Oil for Children With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Clobetasol propionate 0.05% Topical Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant|HIV
Interventions: DRUG: Bdq, Lzd, Lfx, Dlm, Cfz (9-12 months)|DRUG: Bdq, Lzd, Lfx, Cfz, Cs (9-12 months)|DRUG: Bdq, Lzd, Lfx, Z, Dlm (9-12 months)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Intervention to Improve HIV Pre-exposure Prophylaxis Initiation, Adherence and Linkage to Care for Recently Incarcerated Men Who Inject Drugs.
Status: NOT_YET_RECRUITING
Conditions: Hiv|Substance Use Disorders
Interventions: BEHAVIORAL: PrEPared for Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers|Recurrent Glioma|Brain Metastases From Extra-cranial Solid Tumors
Interventions: DRUG: [F-18]MeFAMP PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ferinject® Assessment In GastRectomy Patients With Acute Isovolemic Anemia (FAIRY)
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Ferinject®|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lung Dispersing, Turbid Descending and Gut Clearing Decoction for Bronchiectasis
Status: UNKNOWN
Conditions: Bronchiectasis Adult|Traditional Chinese Medicine|Quality of Life|Exacerbation
Interventions: COMBINATION_PRODUCT: Traditional Chinese Medicine (TCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Antibody and PARP Inhibitor in Extensive Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Camrelizumab Anti-PD-1 antibody Fluzoparib PARP inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT