pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: BI 207127 high dose|DRUG: Faldaprevir|DRUG: Ribavirin|DRUG: BI 207127 low dose|DRUG: Faldaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Aripiprazole Intramuscular Injection in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Management of Obstructive Sleep Apnea (OSA) in Children and Maxillary and Mandibular Development
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Rapid palatal expansion|DEVICE: MGA™ system|DEVICE: Yoobreath™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: venetoclax combined with decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of a Fasting- Mimicking Diet in Periodontitis: A Feasibility Study
Status: COMPLETED
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Fast mimicking diet group|PROCEDURE: Normal diet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Patient Vulvodynia Outcomes
Status: COMPLETED
Conditions: Vulvodynia|Vulvodynia, Generalized|Vulvar Vestibulitis
Interventions: OTHER: Active Acupuncture|OTHER: Placebo Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlling Rapid Atrial Fibrillation With Dexmedetomidine
Status: TERMINATED
Conditions: Rapid Atrial Fibrillation|Heart Rate Control
Interventions: DRUG: Dexmedetomidine Hydrochloride|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
Status: WITHDRAWN
Conditions: Adenotonsillar Hypertrophy|Tonsillitis|Obstructive Sleep Apnea
Interventions: DEVICE: Floseal tonsillectomy|DEVICE: Coblation tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Physician Directed Education on Patient Compliance With Hepatitis C Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C|Genotype 1
Interventions: PROCEDURE: Educational Intervention|OTHER: Patient education and management skills training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture and Diet Modification on amenorrheaIN FEMALE ATHLETE TRIAD
Status: WITHDRAWN
Conditions: Female Athlete Triad
Interventions: OTHER: Acupuncture|DIETARY_SUPPLEMENT: Diet supplementary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns
Status: COMPLETED
Conditions: Pain|Opioid Use
Interventions: BEHAVIORAL: PainTracker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Integrated Intervention for Caregivers--Pilot RCT
Status: COMPLETED
Conditions: Distress; Maternal|Self Efficacy|Parenting|Suicide
Interventions: BEHAVIORAL: Electronic and Care Support Manager Contact|BEHAVIORAL: Enhanced Treatment-as-usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subarachnoid Block With Ultrasound-Guided Transversalis Fascia Plane Block for Cesarean Section
Status: COMPLETED
Conditions: Caesarean Section|Pain, Acute
Interventions: DRUG: Bupivacaine Hcl 0.25% Inj|DRUG: saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial
Status: RECRUITING
Conditions: Acute Pain Due to Trauma|Analgesia|Fentanyl|Esketamine|Emergency Medical Services
Interventions: DRUG: Fentanyl Citrate|DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous T-Cell Lymphoma|Mature T-cell Malignancies|Peripheral T-Cell Lymphoma|Relapsed/ Refractory T-cell Malignancies
Interventions: DRUG: Romidepsin|DRUG: Lenalidomide|DRUG: CC-486 (5-azacitidine)|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Versus General Anesthesia on Postoperative Pulmonary Complications
Status: RECRUITING
Conditions: Pulmonary Complication|Anesthesia|Hip Fractures
Interventions: PROCEDURE: spinal anesthesia|PROCEDURE: general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease
Interventions: BEHAVIORAL: Preventing Loss of Independence through Exercise (PLIE)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Botulinum Toxin A on Neurogenic Detrusor Overactivity in Chronic Spinal Cord Injured Patients
Status: COMPLETED
Conditions: Neurogenic Bladder
Interventions: DRUG: OnabotulinumtoxinA 200 UNT|DIAGNOSTIC_TEST: Urothelial sensory protein levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Sacubitril/Valsartan on Cardiac Oxygen Consumption and Efficiency of Cardiac Work in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: sacubitril/valsatran|DRUG: valsartan|DRUG: placebo to valsartan|DRUG: placebo to sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepato-pancreato-biliary Abnormalities in Fibrous Dysplasia of Bone/McCune Albright Syndrome
Status: RECRUITING
Conditions: Fibrous Dysplasia of Bone
Interventions: OTHER: Screening for hepato-bilio-pancreatic abnormalities in Fibrous dysplasia of bone /McCune Albright syndrome , description and characterization of the lesions.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Burden of Respiratory Illnesses in Pediatric Intensive Care Unit and Its Outcome
Status: NOT_YET_RECRUITING
Conditions: Respiratory Illnesses
Interventions: DIAGNOSTIC_TEST: Complete blood count (CBC), C reactive protein (CRP(., Chest x ray, ABG, Electrolytes, Random blood sugar, Creatinine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery
Status: TERMINATED
Conditions: Osteosarcoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Coadministered Artesunate plus Amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restritive and Liberal Fluid Management and Colonoscopy
Status: RECRUITING
Conditions: Intravenous Infusions|Colonoscopy|Sedoanalgesia
Interventions: OTHER: Colonoscopy|OTHER: Sedoanalgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Therapeutic Effect Between Head-point Acupuncture and Conventional Body Acupuncture on Insomnia
Status: UNKNOWN
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: PROCEDURE: head acupoints acupuncture|PROCEDURE: body acupoints acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare S-1 Plus Oxaliplatin to S-1 as Adjuvant Chemotherapy After D2 Resection in Patients With Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: S-1 plus oxaliplatin|DRUG: S-1 single
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2006/2007) When Administered to Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Surface Antigen, Inactivated, (Adjuvanted with MF59C.1), form. 2006-07
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Usefulness of Integrative Medicine Tools As Adjunctive Care for Women After Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Integrative Therapies Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PTCy and and Ruxolitinib for GVHD Prophylaxis After HSCT With Thymoglobulin in Conditioning Regimen in Patients With Inborn Errors of Immunity
Status: RECRUITING
Conditions: Inborn Errors of Immunity
Interventions: DRUG: Cyclophosphamide|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BPDO-1603 Intervention Trial in Patients With Moderate-to-severe Alzheimer's Disease
Status: UNKNOWN
Conditions: Moderate-to-severe Alzheimer's Disease
Interventions: DRUG: BPDO-1603
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability Study of SG2000 in the Treatment of Advanced Chronic Lymphocytic Leukemia and Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia
Interventions: DRUG: SG2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes|Keratoconjunctivitis Sicca
Interventions: DRUG: carboxymethylcellulose 0.5% , glycerin 0.9% (OPTIVE® MD)|DRUG: sodium hyaluronate 0.18% (VISMED® Multi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Center, Clinical Study to Evaluate the Safety of a Non-Fragranced Personal Lubricant in Healthy Female Subjects
Status: COMPLETED
Conditions: Erythema|Edema
Interventions: DEVICE: Miami w/o frag Personal lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Delicious Eating for Life in Southern Homes
Status: COMPLETED
Conditions: Weight Loss|Diet, Healthy|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Med-South Weight Loss Intervention|BEHAVIORAL: WW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Diponecaftor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uniportal VATS Resection for Pulmonary Aspergilloma : Evaluation of Prognostic Factors in a Single Center Experience
Status: COMPLETED
Conditions: Pulmonary Aspergillosis|Surgery-Complications|Thoracic Diseases
Interventions: PROCEDURE: Uniportal VATS approach|PROCEDURE: VATS approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tranexamic Acid in Brain Tumor Resections
Status: UNKNOWN
Conditions: Brain Tumors|Neoplasms|Gliomas|Astrocytomas|Meningiomas
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab and Chemotherapy Combined With Endoscopic Surgery for Recurrent Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Recurrent Nasopharyngeal Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Chemotherapy|PROCEDURE: endoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SEroma Reduction pOst MAstectomy "SEROMA Study"
Status: UNKNOWN
Conditions: Seroma Complicating A Procedure|Hematoma Postoperative|Breast Cancer
Interventions: DRUG: Tranexamic Acid 100mg/mL, 20mL topical|DRUG: Normal Saline Flush, 0.9%, 20mL topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maraviroc and NeuroAIDS Pathogenesis
Status: COMPLETED
Conditions: AIDS Dementia Complex
Interventions: DRUG: Maraviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Pan-Asian Women
Status: COMPLETED
Conditions: Controlled Ovarian Simulation
Interventions: DRUG: Follitropin alfa|DRUG: Follitropin delta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trail of Demethylation Drug Combined With Chemotherapy in Intermediate-risk AML
Status: RECRUITING
Conditions: Leukemia, Myeloid
Interventions: DRUG: Decitabine and Ara-C|DRUG: Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Pelvic and Prostatic SIB-IMRT With Long-term Androgen Deprivation for High Risk Localized Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: RADIATION: Simultaneous integrated boost intensity-modulated arctherapy|DRUG: Androgen deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Tolerability of ART-123 + FOLFOX + Bevacizumab in Metastatic Colorectal Cancer Patients
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: thrombomodulin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
Status: NOT_YET_RECRUITING
Conditions: Presbylarynx|Aspiration|Spasmodic Dysphonia|Globus Pharyngeus|Larynx Paralysis|Laryngeal Disease|Vocal Cord Paralysis|Iatrogenic Injury|Sensory Neuropathy
Interventions: DEVICE: Cheung-Bearelly Aesthesiometer|PROCEDURE: Transnasal Laryngoscopy|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Learn More About How Radium-223 is Being Used With Other Treatments in European Patients Who Have Not Received Radium-223 Before
Status: COMPLETED
Conditions: Bone Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Radium 223 dichloride (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laminaria and Misoprostol Before Operative Hysteroscopy
Status: UNKNOWN
Conditions: Cervical Spasm
Interventions: DEVICE: Laminaria tent|DRUG: Laminaria plus Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
Status: RECRUITING
Conditions: Chemotherapy Effect|Dental Caries|Malocclusion|Childhood Cancer|Tooth Defect
Interventions: DIAGNOSTIC_TEST: Clinical and radiographic dental examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HAIC Combined With Cadonilimab and Regorafenib as 2nd-line Treatment for ICC
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: HAIC-GEMOX+Cadonilimab+Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP vs PRP Plus IGF for Patellar Tendinosis
Status: COMPLETED
Conditions: Tendinopathy|Patellar Ligament|Platelet-Rich Plasma
Interventions: DEVICE: Platelet Rich Plasma|DEVICE: Platelet Rich Plasma plus IGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Induction With Basiliximab Versus No-Induction in Low Immunological Risk Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplantation
Interventions: DRUG: Basiliximab 20 milligram [Simulect]|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscular Deficits of Diabetic Myopathy
Status: RECRUITING
Conditions: Diabetes Mellitus|Obesity|Chronic Hyperglycaemia|Weight Loss|Diabetic Myopathy|Sarcopenia
Interventions: DRUG: 6-months of medically assisted glycemic improvement|PROCEDURE: Bariatric surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of an Endoscopic Treatment of the Line Z on the Gastronomic Recurrence and the Gastro- Esophageal Reflux Disease in the Care of the Adenocarcinoma of Barrett's Oesophagus
Status: UNKNOWN
Conditions: Barrett Esophagus Adenocarcinoma
Interventions: PROCEDURE: Complete endoscopic resection at Day 1 and months 2, 4, 6 8 and month 10.|DEVICE: Endoscopic resection at month 2 and month 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Two Dissolvable Therapeutics Under Removable Partial Dentures
Status: COMPLETED
Conditions: Edentulous Jaw|Edentulous Mouth
Interventions: DEVICE: MI Paste, then, Biotene Dry Mouth Gel|DEVICE: Biotene Dry Mouth Gel, then, MI Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Three Prosthesis Designs in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Gonarthrosis; Primary|Degenerative Joint Disease of Knee
Interventions: PROCEDURE: Knee arthroplasty, Cruciate retaining|PROCEDURE: Knee arthroplasty, Anterior stabilized|PROCEDURE: Knee arthroplasty, Posterior stabilized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lubricity Post-Wear - Competitive Lenses Pilot
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Narafilcon A contact lenses|DEVICE: Stenfilcon A contact lenses|DEVICE: Somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Early Prediction and Randomised Prevention of Preeclampsia With Low Dose Aspirin in Chinese Cohort
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- and Postmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Urinary Tract Infections
Interventions: DIAGNOSTIC_TEST: Blood and urine sample evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Reducing Total Volume of Sprint Exercise on Circulating Levels of BDNF
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Sprint interval training (SIT)|BEHAVIORAL: Reduced-exertion high-intensity interval training (REHIT|BEHAVIORAL: No-exercise control (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: Tislelizumab|RADIATION: Short-course radiotherapy|DRUG: Capecitabine+Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of the Safety and Tolerability of REGN668(SAR231893) in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: REGN668
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hereditary Tubulointerstitial Nephritis
Status: COMPLETED
Conditions: Nephritis, Interstitial|Chronic Renal Failure|Gout|Renal Cysts
Interventions: OTHER: Blood and urine sample collections
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Finnish Unicompartmental and Total Knee Arthroplasty Investigation
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Unicondylar Knee Replacement|PROCEDURE: Total Knee Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Bisoprolol Vs IV Diltiazem in Atrial Fibrillation or Flutter With Rapid Ventricular Rate.
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation With Rapid Ventricular Response|Atrial Flutter With Rapid Ventricular Response
Interventions: DRUG: Oral Bisoprolol|DRUG: Intravenous Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Pops-titration Versus the Slow-coagulation Cyclophotocoagulation in Treatment of Refractory Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Intraocular Pressure
Interventions: PROCEDURE: The pops-titration group|PROCEDURE: The slow-coagulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
Status: ACTIVE_NOT_RECRUITING
Conditions: Wrinkle
Interventions: OTHER: Cleansing Balm|OTHER: Toning Essence|OTHER: Facial Serum|OTHER: Moisturizer|OTHER: Eye Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes|Post-menopause
Interventions: OTHER: Aerobic Exercise|OTHER: Resistance Exercise|OTHER: No exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Driver Education Research Study
Status: RECRUITING
Conditions: Risk Reduction Behavior|Injuries|Accident, Traffic|Development, Adolescent
Interventions: BEHAVIORAL: Online Vehicle and Driver Safety Training|BEHAVIORAL: Online Driver Skills Training|BEHAVIORAL: Behind-the-Wheel Driver Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MBRP + Vortioxetine VS MBRP on Preventing Relapse in Chronic MA Users
Status: UNKNOWN
Conditions: Relapse|Cognitive Impairment|Depression
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Benign-Malign Differentiation of Axillary Lymph Nodes: The Role Of Superb Microvascular Imaging
Status: COMPLETED
Conditions: Diagnosis|Axilla; Breast
Interventions: DIAGNOSTIC_TEST: Ultrasound and biyopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Arthroscopic Synovectomy of the Wrist in Inflammatory Arthritis
Status: RECRUITING
Conditions: Wrist Arthritis|Psoriatic Arthritis|Rheumatoid Arthritis|Surgery
Interventions: PROCEDURE: Arthroscopic synovectomy of the wrist|DRUG: Intra-articular corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|OTHER: Communication Intervention|OTHER: Comprehensive Geriatric Assessment|OTHER: Electronic Health Record Review|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeting DNA-methylation Fingerprints Linked to Ultra-Processed Foods Consumption to Prevent Non-communicable Diseases: the METHYL-UP Study
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: OTHER: Nutritional intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of CML-CP Patients Treated With Asciminib Versus Best Available Therapy, Previously Treated With 2 or More Tyrosine Kinase Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Chronic Myelogenous
Interventions: DRUG: asciminib|OTHER: best available treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Versus Systemic Thrombolysis for Acute Ischemic Stroke (SYNTHESIS)
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident
Interventions: DRUG: local interarterial recombinant tissue plasminogen activator|DRUG: intravenous (IV) rt-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgo-Sedative Effects Of Oral, Or Nebulized Ketamine In Pre-schoolers Undergoing Elective Surgery.
Status: COMPLETED
Conditions: Conscious Sedation|Postoperative Analgesia
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Detection of Sub-Clinical Atrial Fibrillation in Defibrillator Patients With the Use of a VDD-ICD Lead
Status: UNKNOWN
Conditions: Cardiac Arrhythmias|Atrial Fibrillation and Flutter|Cardiovascular Diseases|Implantable Cardioverter-Defibrillators
Interventions: DEVICE: VDD ICD (experimental group)|DEVICE: Single chamber VVI ICD (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma Multiforme|Progressive Glioblastoma Multiforme|Anaplastic Astrocytoma or Gliosarcoma
Interventions: BIOLOGICAL: M032 (NSC 733972)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of COVID-19 Infection to Severe Pneumonia or ARDS
Status: UNKNOWN
Conditions: Covid19 Pneumonia
Interventions: DRUG: EC-18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Determine Safety and Effectiveness of KEEPASLEEP Device in Simple Snorers.
Status: UNKNOWN
Conditions: Snoring|Sleep Apnea Syndromes
Interventions: DEVICE: KEEPASLEEP enhanced breathing device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: User Evaluation of Advanced Personalized Modular Pressure Relief Seating Cushion Systems
Status: NOT_YET_RECRUITING
Conditions: Mobility Impairment
Interventions: DEVICE: Use of GEL BALL FITTED MODULAR CUSHION|DEVICE: Use of SQUISHINS FITTED MODULAR CUSHION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Antigen Rapid Test Screening to Prevent SARS-CoV-2 Transmission (COVID-19) at Mass Gathering Events.
Status: WITHDRAWN
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 antigen rapid test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomised Trial of Dolutegravir (DTG)-Based Antiretroviral Therapy vs. Standard of Care (SOC) in Children With HIV Infection Starting First-line or Switching to Second-line ART
Status: UNKNOWN
Conditions: HIV Infection
Interventions: DRUG: DTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connective Tissue Matrix for Rotator Cuff Tendinopathy
Status: RECRUITING
Conditions: Tendinopathy|Shoulder Pain|Rotator Cuff Tendinitis|Rotator Cuff Tendinosis
Interventions: BIOLOGICAL: CTM Boost|BIOLOGICAL: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Vinorelbine and Oral Capecitabine as Treatment for Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Vinorelbine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Respiratory Training in Lymphoma Survivors
Status: RECRUITING
Conditions: Hodgkin Lymphoma|Non Hodgkin Lymphoma
Interventions: DEVICE: Inspiratory muscle strength training|DEVICE: Sham Inspiratory muscle strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of the Face Mask and Oral Mask Ventilation After Nasal Surgery
Status: COMPLETED
Conditions: Nasal Septum Deviation
Interventions: DEVICE: Face Mask|DEVICE: Oral Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment
Status: RECRUITING
Conditions: HIV Infection Primary
Interventions: DRUG: Dasatinib 70 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Pneumatic Compression Device for the Treatment of Venous Ulcers and Lymphedema
Status: TERMINATED
Conditions: Lymphedema
Interventions: OTHER: Flexitouch for 1 month in addition to routine wound care|OTHER: Routine wound care for venous ulcers and lymphedema|DEVICE: Flexitouch pneumonic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Lung Protective Extubation Following General Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Intra-abdominal Surgery|Anesthesia|Lung Injury|Ventilator-Induced Lung Injury|Atelectasis
Interventions: OTHER: Protective "open-lung" extubation|OTHER: Conventional extubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery
Status: COMPLETED
Conditions: Endovascular Carotid Surgery|Preoperative Hypotension
Interventions: DRUG: ephedrine and phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prospective Analysis of Intraoperative AMNIOGEN® Injection in Patients With Rotator Cuff Tear
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: DRUG: AMNIOGEN|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Nutritional Supplement Lycoderm on Its Impact on Skin Parameters
Status: COMPLETED
Conditions: Skin Care
Interventions: DIETARY_SUPPLEMENT: Lycoderm|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of CV4 and Rib Raising Techniques on Autonomic Balance
Status: COMPLETED
Conditions: Autonomic Nervous System Disease|Osteopathy
Interventions: OTHER: CV4 technique|OTHER: RR technique|OTHER: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Pediatric Asthma Care Through Inhaled Steroids in Schools
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Inhaled steroids in school.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Platelet-rich Plasma (PRP) Treatment for Medial Retinaculum Tear Post Medial Patellar Dislocation
Status: COMPLETED
Conditions: Patella-Dislocation
Interventions: BIOLOGICAL: Plasma Rich in Growth Factors (PRGF)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance of Healthy, Term Infants to Infant Formulas
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Milk based formula A|OTHER: #2 Standard formula|OTHER: #3 Human Milk|OTHER: Milk based formula C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Larazotide Acetate to Treat Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Larazotide acetate|DRUG: Placebo|DIETARY_SUPPLEMENT: Gluten 900 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrosorb® Versus Control in the Management of Radio-induced Skin Toxicity: Multicentre Controlled Phase III Randomized Trial
Status: COMPLETED
Conditions: Breast Cancer|Radiation Dermatitis
Interventions: DEVICE: Castalie water spray|DEVICE: Hydrogel Hydrosorb®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: DCCR|DRUG: DCCR|DRUG: Placebo for DCCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ-12420|DRUG: Esomeprazole 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sanofi Pasteur's Tdap Combined Vaccine as a Booster Versus Local DT Vaccine in Children or Versus Local Td Vaccine in Adolescents and Adults in China.
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Tdap (ADACEL)|BIOLOGICAL: DT vaccine (Diphtheria and Tetanus Combined Vaccine, Adsorbed)|BIOLOGICAL: Td vaccine (Diphtheria and Tetanus Combined Vaccine for Adults and Adolescents, Adsorbed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Multifactorial Intervention to Reduce Physical Restraints for Care Providers in Nursing Homes
Status: COMPLETED
Conditions: Nursing Homes|Intervention|Older People
Interventions: OTHER: multifactorial interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peripheral Mechanisms of Humoral Immune Effector-mediated Tourette's Syndrome and the Role of Tuina Intervention
Status: RECRUITING
Conditions: Tourette Syndrome in Children|Food Intolerance|Inflammatory Response
Interventions: OTHER: Spine manipulation; westren medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK Study of Pregabalin GLARS Tablet 150mg and IR Formulation After Multiple Dosing Under Fed Condition in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin 150mg|DRUG: Pregabalin 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interdisciplinary Intervention With Motivational Approach in Adolescents With Overweight and Obesity.
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Lifestyle modification and cardiovascular risk|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Care of Comorbid Obesity and Depression
Status: COMPLETED
Conditions: Obesity|Depression
Interventions: BEHAVIORAL: Structured behavioral weight loss group|BEHAVIORAL: Weight loss and cognitive-behavioral depression group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera
Status: COMPLETED
Conditions: Essential Thrombocythemia|Polycythemia Vera
Interventions: DRUG: Imetelstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function
Status: COMPLETED
Conditions: Joint Function Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3 and/or botanical ingredient|OTHER: Control product consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pediatric Continuity Care Intensivist
Status: COMPLETED
Conditions: Critical Illness
Interventions: BEHAVIORAL: Continuity Care Intensivist Communication Training|BEHAVIORAL: Continuity Care Intensivist (CCI) Provider Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Comparative Efficacy and Safety of Two General Anesthesia Protocols Consisting of Fentanyl Plus Propofol Plus Rococuronium Plus Isoflurane Versus Ketamime Plus Magnesium Sulphate Plus Lidocaine Plus Clonidine Plus Propofol Plus Rococuronium Plus Isoflurane for Gynaecology Surgery in Cameroon
Status: UNKNOWN
Conditions: Opioids|Clinical Trial|Anesthesia|Gynecology|Surgery
Interventions: DRUG: Opiod Free Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pilot rTMS for AUD+mTBI
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder|Mild Traumatic Brain Injury|Post-traumatic Stress Disorder
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy +/- Radiation in High Risk Hodgkin's Disease
Status: TERMINATED
Conditions: Hodgkin Disease
Interventions: DRUG: Doxorubicin|DRUG: Vinblastine|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Vincristine|DRUG: Bleomycin|DRUG: Gemcitabine|DRUG: Vinorelbine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT