pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of DEP114 in the Treatment of Moderate to Severe Persistent Allergic Rhinitis in Children.
Status: NOT_YET_RECRUITING
Conditions: Allergic Rhinitis
Interventions: DRUG: DEP114|DRUG: Desloratadine 0.5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Celecoxib Activity in Mycobacterium Tuberculosis: A Whole Blood Bactericidal Activity Study in Healthy Volunteers
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Celecoxib|DRUG: Rifampicin|DRUG: Pyrazinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Dose, Efficacy and Safety of Setrusumab in Participants With Osteogenesis Imperfecta
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteogenesis Imperfecta
Interventions: BIOLOGICAL: Setrusumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Intersectional Viborg Screening Program: Cost-(Effectiveness) of Screening for Diabetes and Cardiovascular Diseases
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Aortic Aneurysm, Abdominal|Hypertension|Mass Screening|Peripheral Arterial Disease|Arrythmia|Diabetes|Carotid Atherosclerosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serum Progesterone Level in HRT-FET：a RCT
Status: UNKNOWN
Conditions: Progesterone,Hormone Replacement Thawed Embryo Transfer Cycles
Interventions: DRUG: intramuscular progesterone 20-40mg from D3 until pregnancy test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Simultaneous Posterior Colporrhaphy and Perineoplasty on the Efficiency and Safety of Mesh-augmented Sacrospinal Fixation (Apical Sling) in Advanced POP Repair.
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Mesh-augmented sacrospinal fixation with posterior colporrhaphy and perineoplasty.|PROCEDURE: Mesh-augmented sacrospinal fixation with posterior colporrhaphy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Metabolic Effects of Polylactose: A Novel Prebiotic
Status: NOT_YET_RECRUITING
Conditions: Obesity, Adolescent|Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: Polylactose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rate Control in Patients With Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Rate Control|Cardiopulmonary Exercise Test
Interventions: DRUG: Atenolol, Bisoprolol, Metoprolol, Nebivolol, Propranolol, Diltiazem, Verapamil, digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Blood Flow Restriction on Football-Related Performance Parameters
Status: COMPLETED
Conditions: Vascular Occlusion|Soccer|Exercise|EMG
Interventions: OTHER: Blood Flow Restriction|OTHER: Classical Training Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Augmenting the Effects of Mirror Therapy for Stroke Rehabilitation by tDCS
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: apply a-tDCS on the ipsilesional M1 followed by MT (M1-Seq)|BEHAVIORAL: apply a-tDCS on the ipsilesional PMC followed by MT (PMC-Seq)|BEHAVIORAL: MT only with sham tDCS (MT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Liraglutide on Bone Turnover, Bone Mass and Bone Cell Function
Status: COMPLETED
Conditions: Diabetes Complications|Osteoporosis
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle
Status: UNKNOWN
Conditions: Endometrial Receptivity and Success Rate of IVF
Interventions: PROCEDURE: Endometrial biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reversal With Low Doses of Sugammadex in Patients Undergoing Non-cardiac Surgery
Status: UNKNOWN
Conditions: Postoperative Residual Curarization|Neuromuscular Block
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prednisone Plus IVIg vs. Prednisone for ITP During Pregnancy
Status: RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Prednisone|DRUG: IVIg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Visio-behavioral Scale to Evaluate Visual Abilities of Patients With Profound Multiple Intellectual Disabilities (PLH-Vision)
Status: COMPLETED
Conditions: Profound Multiple Intellectual Disabilities
Interventions: BEHAVIORAL: Visual-behavioral Scale at day 1|BEHAVIORAL: Test-retest at the end of 2 weeks|BEHAVIORAL: Test at 6 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Envafolimab, Lenvatinib Combined With TACE in the Treatment of Unresectable Locally Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Objective Response Rate (ORR)
Interventions: DRUG: Envafolimab, Lenvatinib Combined With TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Enzalutamide to First Line Docetaxel for Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Prednisone|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALD-301 for Critical Limb Ischemia, Randomized Trial
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Arterial Disease|Peripheral Vascular Disease
Interventions: PROCEDURE: ALDH-br bone marrow cells vs. mononuclear bone marrow cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Status: RECRUITING
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Ciliary Body Thickness in Patients With Diabetic Macular Edema After Vitrectomy
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Pars Plana Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Lenalidomide/Ixazomib/Dexamethasone/Daratumumab in Transplant-Ineligible Patients With Newly Diagnosed MM
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloma, Multiple
Interventions: DRUG: Lenalidomide|DRUG: Ixazomib|DRUG: Daratumumab Injection|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training Given to Caregivers of Stroke Home Care Patients.
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Educational intervention based on the Precede-Proceed Model for individuals caring for stroke home care patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Ranging Safety and Efficacy Study of Topical Creams Containing API 31510 for the Treatment of in Situ Cutaneous Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: API 31510 Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness and Safety of Supratube Device
Status: COMPLETED
Conditions: Intensive Critical Unit|Pneumonia|Aspiration|Prevention and Control
Interventions: DEVICE: Supranav
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness Study of Psychotherapy in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
Status: TERMINATED
Conditions: Heart Defects, Congenital
Interventions: DRUG: nesiritide|DRUG: milrinone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of β-hydroxybutyrate on Working Skeletal Muscle
Status: RECRUITING
Conditions: Aging|Metabolism Disorder|Ketonemia|Muscle Disorder
Interventions: DIETARY_SUPPLEMENT: D-β-hydroxybutyrate/D 1,3 butanediol monoester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Market Research - Acceptability Study for a New PKU Protein Substitute
Status: COMPLETED
Conditions: PKU|Phenylketonurias|Inborn Errors of Metabolism|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: GMPOWER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Manualized Group Cognitive-behavioral Therapy for Social Anxiety in First Episode Psychosis
Status: COMPLETED
Conditions: Social Phobia|Psychosis
Interventions: BEHAVIORAL: Manualized group Cognitive-behavioral therapy (CBT) for social anxiety in first episode psychosis|BEHAVIORAL: Group Computer assisted cognitive remediation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging of Vesicular Acetylcholine and Dopamine Transporters in Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies
Interventions: OTHER: Imaging with IBVM|OTHER: Imaging with DATSCAN|BEHAVIORAL: neuropsychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement
Interventions: BIOLOGICAL: iprf|PROCEDURE: MOPs with leveling and alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Primary Plasma Cell Leukemia
Interventions: BIOLOGICAL: CT071
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Single and Repeated Dose Escalation Study of SAR442501 in Healthy Adults Subjects
Status: COMPLETED
Conditions: Osteochondrodysplasia
Interventions: DRUG: SAR442501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sulforaphane as an Antagonist to Human PXR-mediated Drug-drug Interactions
Status: COMPLETED
Conditions: Adverse Drug Interactions
Interventions: DRUG: Rifampicin|DIETARY_SUPPLEMENT: sulforaphane plus rifampicin|DIETARY_SUPPLEMENT: sulforaphane alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lamivudine and Adefovir to Treat Chronic Hepatitis B
Status: COMPLETED
Conditions: HBV (Hepatitis B Virus)|Hepatitis B|Hepatitis
Interventions: DRUG: Lamivudine and adefovir|DRUG: Adefovir alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA
Status: COMPLETED
Conditions: Primary Hyperoxaluria Type 1|Idiopathic Hypercalciuria
Interventions: OTHER: Urines samples|OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Improves Functional Outcomes in Acute Stroke Patients
Status: UNKNOWN
Conditions: Stroke, Acute
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage IV Melanoma
Status: TERMINATED
Conditions: Stage IV Melanoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Therapeutic Management in ESBL-infected Patients or Carriers by Providing and Sharing a Free Tool - the "ESBL toolKIT"and Interventional Study of a Prospective Cohort of HIV+ Patients Searching for Possible Sexual Transmission Factors in ESBL Carriers
Status: COMPLETED
Conditions: AIDS Patients
Interventions: OTHER: HIV seropositive patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes
Status: COMPLETED
Conditions: Sarcoma|Leiomyosarcoma|Malignant Fibrous|Histiocytoma|Angiosarcoma
Interventions: DRUG: gemcitabine|DRUG: docetaxel|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Computerized Intervention for Learning to Re-Evaluate Suicidal Thoughts
Status: TERMINATED
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Re-Evaluating Suicidal Thoughts|BEHAVIORAL: Healthy Social Living
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Land- and Water-Based Core and Lower Extremity Strength Training in Improving the Jump Performance Among Volleyball and Basketball Players
Status: COMPLETED
Conditions: Athletes
Interventions: OTHER: Combined Land- and Water-Based Exercise|OTHER: Land-Based Exercise|OTHER: Water-Based Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thymectomy
Status: NOT_YET_RECRUITING
Conditions: RATS Surgery|Thymectomy|Locoregional Anesthesia|Postoperative Pain Management|Serratus Posterior Superior Intercostal Plane Block|Robotic-Assisted Thoracoscopic Surgery
Interventions: PROCEDURE: Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block performed with 0.25% bupivacaine|PROCEDURE: Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block performed with a placebo solution (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Oncogenetics in Breast Cancer in Reunion Epidemiology of Breast Cancer in Reunion: Study of the Reunion Mutation on BRCA2
Status: RECRUITING
Conditions: Breast Cancer|Genetic Disease|BRCA2 Mutation
Interventions: GENETIC: blood sample for BRCA2 mutation detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Therapy of Posterior Subtenon Triamcinolone Acetonide and Intravitreal Bevacizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Branch Retinal Vein Occlusion
Interventions: PROCEDURE: intravitreal bevacizumab monotherapy|PROCEDURE: combined therapy of posterior subtenon triamcinolone acetonide and intravitreal bevacizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Double Balloon Interventional Platform (DiLumen) for Complex Colonic ESD
Status: COMPLETED
Conditions: Colonic Polyp
Interventions: DEVICE: double balloon interventional platform (DiLumen)|DEVICE: no double balloon interventional platform (DiLumen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Progesterone Receptors in Breast Carcinoma by Positron Emission Tomography (PET) Using Fluoro Furanyl Norprogesterone (FFNP)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: PET|OTHER: Laboratory Testing|OTHER: Safety Testing|DRUG: F18-FFNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
Status: RECRUITING
Conditions: Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer|Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of Vaccine Therapy in Patients With Indolent Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Follicular|Lymphoma, Small Lymphocytic
Interventions: DRUG: autologous human tumor-derived HSPPC-96
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors
Status: COMPLETED
Conditions: Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma|Peripheral Primitive Neuroectodermal Tumor
Interventions: DRUG: trabectedin|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Acnase Creme in the Treatment of Acne Vulgaris I and II
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: Benzoyl Peroxide 5% and Sulphur 2%|DRUG: Vehicle of Acnase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetic Kidney Disease|Type 1 Diabetes
Interventions: DRUG: Semaglutide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder
Status: NOT_YET_RECRUITING
Conditions: Borderline Personality Disorder|Self-harm|Non-suicidal Self-injury|Suicide
Interventions: OTHER: High degree of long (>5 days) and/or compulsory psychiatric inpatient care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relative Bioavailability of Dextromethorphan Syrup in Comparison to Dextromethorphan Soft Pastilles in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dextromethorphan syrup|DRUG: Dextromethorphan soft pastilles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels
Status: RECRUITING
Conditions: Sedentary Behavior|Aging|Sarcopenia|Amino Acids|Dietary Protein
Interventions: BEHAVIORAL: Habitual Physical Activity|BEHAVIORAL: Step-Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: AG-120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLACS vs Phaco in Shallow Anterior Chamber
Status: COMPLETED
Conditions: Cataract Surgery|Shallow Anterior Chamber|Phacoemulsification
Interventions: PROCEDURE: Phacoemulsification Cataract SUrgery|PROCEDURE: Femtosecond Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Neo-Adjuvant Everolimus to Treat Advanced Renal Cell Carcinoma - Analysis of Biomarkers
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Transtek Body Fat Analyzer (GBF-835-N2 & Other 7 Models)
Status: COMPLETED
Conditions: Weight|Body Fat Disorder
Interventions: DEVICE: Transtek DUT|DEVICE: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Short Term Surgical Outcomes of Anatomical Versus Non Anatomical Laparoscopic Liver Resection for Liver Tumors
Status: ENROLLING_BY_INVITATION
Conditions: Liver Neoplasms
Interventions: PROCEDURE: Anatomical laparoscopic liver resection for liver neoplasms|PROCEDURE: Non-Anatomical laparoscopic liver resection for liver neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Soft Tissue Biased Manual Therapy and Conventional Physical Therapy in Patients With Frozen Shoulder
Status: COMPLETED
Conditions: Frozen Shoulder|Shoulder Adhesive Capsulitis
Interventions: OTHER: Soft tissue biased manual therapy group|OTHER: Conventional physical therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zinc Supplementation on Botox Treated Forehead Rhytids
Status: NOT_YET_RECRUITING
Conditions: Adjuvant Zinc May Increase the Efficacy of Botulinum Toxin|Zinc Supplementation for Botulinum Toxin Treatment of the Forehead|Glabellar Frown Lines|Botulinum Toxin, Cosmetic|Adjuvant Oral Zinc and Botulinum Toxin
Interventions: DIETARY_SUPPLEMENT: zinc citrate 50 mg|OTHER: Placebo Microcrystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density
Status: WITHDRAWN
Conditions: Diabetes Mellitus|Corneal Endothelial Cell Loss|Dexamethasone Adverse Reaction|Corneal Endothelial Decompensation
Interventions: DRUG: Dexamethasone|DRUG: Saline Solutions, Intraocular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Pectopexy Versus Abdominal Sacral Hysteropexy.
Status: COMPLETED
Conditions: Genital Prolapse
Interventions: PROCEDURE: Abdominal Pectopexy|PROCEDURE: Abdominal Sacral Hysteropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Community Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: BEHAVIORAL: Strategy based on BPS guided antibiotic use|BEHAVIORAL: Enforced Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of NovoClasp for Treating Moderate to Severe and Severe Degenerative Mitral Regurgitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Mitral Valve Disease
Interventions: DEVICE: NovoClasp® transcatheter mitral valve clip and steerable guide catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myeloproliferative Neoplasm|Myelodysplastic/Myeloproliferative Neoplasm
Interventions: DRUG: TAS1553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Better Options for Chronic Cancer Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Cancer Survivor|Opioid Dependence
Interventions: BEHAVIORAL: Multimodal pain care|DRUG: Medication optimization|DEVICE: Buprenorphine rotation|OTHER: Opioid tapering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alexander Technique, Routine Physical Therapy, Balance, Posture, Functional Mobility , Chronic, Hemorrhagic, Stroke
Status: UNKNOWN
Conditions: Chronic Hemorrhagic Stroke
Interventions: OTHER: Alexander Technique + Routine Physical Therapy|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neprilysin Inhibition to Reduce Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Myocardial Fibrosis
Interventions: DRUG: Sacubitril-valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Psychoeducation Intervention for Caregivers of Patients With Bipolar Disorder
Status: TERMINATED
Conditions: Bipolar Disorder Family Members
Interventions: BEHAVIORAL: Psychoeducation|BEHAVIORAL: Psychoeducation - Delayed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Results of Two Surgical Methods for Scleral IOL Implantation and Fixation in Eyes Without Capsular Support: Yamane- Versus 4-flanged Technique
Status: RECRUITING
Conditions: Lens Luxation|IOL Subluxation|IOL Opacification|Aphakia - No Lens Capsule
Interventions: PROCEDURE: Pars plana vitrectomy|PROCEDURE: IOL explantation|PROCEDURE: Scleral IOL fixation Yamane Technique|PROCEDURE: Scleral IOL fixation "4-flanged" Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Soft Tissue Sarcoma|Resectable Soft Tissue Sarcoma|Soft Tissue Sarcoma
Interventions: DRUG: Fluorodopa F 18|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|PROCEDURE: Surgical Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Thymoglobulin|DRUG: Daclizumab|OTHER: Plasmapheresis|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Dexamethasone|DRUG: Prednisone|DRUG: Cytogam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Single Doses of the Motilin Receptor Agonist GSK962040 in Type I Diabetic Patients With Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: GSK962040 25 mg|DRUG: Placebo|DRUG: GSK962040 50 mg|DRUG: GSK962040 1250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: WITHDRAWN
Conditions: Ovarian Papillary Serous Carcinoma|Ovarian Serous Cystadenocarcinoma|Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Primary Peritoneal Cavity Cancer
Interventions: DRUG: metformin hydrochloride|DRUG: carboplatin|DRUG: paclitaxel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ozonized Water With Toothpaste and Mousse in Non Surgical Periodontal Therapy for Patients With Diabetes Mellitus Type 1: a Randomized Clinical Trial.
Status: COMPLETED
Conditions: Diabetes Mellitus With Periodontal Disease
Interventions: OTHER: Peribioma Toothpaste and Mousse|OTHER: Standard toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsatile Intravenous Insulin Therapy on Metabolic Integrity in Patients With Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, With Complications
Interventions: PROCEDURE: Pulsatile Intravenous Insulin Therapy (Humulin R, Novolog)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of EYP-1901 in Patients With Nonproliferative Diabetic Retinopathy (NPDR)
Status: COMPLETED
Conditions: Nonproliferative Diabetic Retinopathy
Interventions: DRUG: EYP-1901|OTHER: Sham IVT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usability Study of "ArmAssist 2.0." Robot: Homecare Arm Rehabilitation in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Rehabilitation|Upper Limb Rehabilitation|Telerehabilitation|Robot-assisted Therapy
Interventions: DEVICE: ArmAssist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in Patients With Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: pramipexole|DRUG: levodopa in combination with benserazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC).
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Ceralasertib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dystonia Genotype-Phenotype Correlation
Status: RECRUITING
Conditions: Dystonia|Dystonia; Idiopathic|Dystonia, Primary|Dystonia, Secondary|Dystonia, Familial|Dystonia Disorder|Dystonias, Sporadic|Dystonia; Orofacial|Dystonia Lenticularis|Dystonia, Paroxysmal|Dystonia 6|Dystonia 5|Dystonia 8|Dystonia 9|Dystonia 19|Dystonia 10|Dystonia 11|Dystonia 20|Dystonia 12|Dystonia, Focal|Dystonia of Head|Dystonia, Diurnal
Interventions: OTHER: Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome
Status: COMPLETED
Conditions: Lennox Gastaut Syndrome
Interventions: DRUG: ZX008 0.2 or 0.8 mg/kg/day|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of GM-CSF in Patients With ALI/ARDS
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DRUG: Placebo|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family-centered Mental Health Promotion Intervention
Status: RECRUITING
Conditions: Stress, Psychological|Stress, Physiological|Anxiety|Depression
Interventions: BEHAVIORAL: Problem Management Plus for Immigrants at family settings|BEHAVIORAL: Talk program with Community Support Service Pamphlet (CSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Clinical Stage I Esophageal Adenocarcinoma AJCC v8|Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage II Esophageal Adenocarcinoma AJCC v8|Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Endoscopic Ultrasound|PROCEDURE: Esophagogastroduodenoscopy|DRUG: Fluorouracil|RADIATION: Hypofractionated Radiation Therapy|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|PROCEDURE: Positron Emission Tomography|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of H5N1 Adjuvanted, Inactivated, Split-Virion Pandemic Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Pandemic Influenza|Influenza A Virus Infection|Orthomyxoviridae Infections
Interventions: BIOLOGICAL: A/H5N1 inactivated, split-virion influenza vaccine+Adjuvant|BIOLOGICAL: A/H5N1 inactivated, split-virion influenza vaccine+Adjuvant|BIOLOGICAL: A/H5N1 inactivated, split-virion influenza vaccine+Adjuvant|BIOLOGICAL: A/H5N1 inactivated, split-virion influenza vaccine+Adjuvant|BIOLOGICAL: A/H5N1 inactivated, split-virion influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics
Status: COMPLETED
Conditions: Periodontal Diseases|Periimplantitis
Interventions: DRUG: Placebo|DRUG: Amoxicillin Sandoz|DRUG: Metronidazole Sanofi|DRUG: Phenoxymethylpenicillin Meda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Care Strategies on Dressing Change-induced Bleeding in Patients With Bleeding Malignant Wounds
Status: NOT_YET_RECRUITING
Conditions: Malignant Wound
Interventions: OTHER: Algosteril|OTHER: Other Dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Tolerability, and Effects of MK-0974 (Telcagepant) on Exercise Tolerance in Patients With Stable Angina (MK-0974-014)
Status: COMPLETED
Conditions: Angina Pectoris|Coronary Heart Disease|Calcitonin Gene-related Peptide Receptor
Interventions: DRUG: telcagepant|DRUG: Placebo to telcagepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Screening Circuit of COVID 19 in Schools, Pilot Study
Status: COMPLETED
Conditions: SARS-CoV-2 (COVID-19)
Interventions: OTHER: Escola L'Horitzó|OTHER: Escola John Talabot
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gynecological Diseases
Status: COMPLETED
Conditions: Cervicovaginitis|Endometriosis|Repeated Implantation Failure
Interventions: OTHER: Biological sample collection|OTHER: Questionnaire|OTHER: Medical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Closed Sinus Augmentation With a Calcium Phosphosilicate Putty
Status: NOT_YET_RECRUITING
Conditions: Dental Implant|Maxillary Sinus Floor Augmentation
Interventions: PROCEDURE: Low volume CBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anakinra as a Rescue Treatment for Allergic Inflammation
Status: WITHDRAWN
Conditions: Asthma, Allergic
Interventions: DRUG: Anakinra|DRUG: Preservative-free 0.9% sodium chloride (Placebo)|BIOLOGICAL: House dust mite allergen|BIOLOGICAL: Cat hair allergen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: KN046|DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: B Acute Lymphoblastic Leukemia|Leukemia Relapse
Interventions: BIOLOGICAL: Collection of blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia
Status: UNKNOWN
Conditions: Epidural Anesthesia|Cesarean Section
Interventions: DRUG: Ropivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vibratory Perineal Stimulus With Transvaginal Electrical Stimulation
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Vibratory Perineal Stimulus|OTHER: Transvaginal Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collagenase in the Treatment of Zone II Flexor Tendon Adhesions in the Hand
Status: COMPLETED
Conditions: Adhesion of Flexor Tendon of Hand
Interventions: DRUG: Collagenase|DRUG: Collagenase injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative PEEP Optimization: Effects on Postoperative Pulmonary Complications and Inflammatory Response
Status: COMPLETED
Conditions: Pulmonary Complications|Inflammatory Response
Interventions: PROCEDURE: Optimal PEEP|PROCEDURE: Standard PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Health Enhancement by Eating Favourable Food
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: WholeFiber|DIETARY_SUPPLEMENT: Kombucha|DIETARY_SUPPLEMENT: Maltodextrin DE19/21
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fisetin to Reduce Senescence and Mobility Impairment in PAD
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Aging|Peripheral Vascular Diseases|Walking, Difficulty
Interventions: DRUG: Fisetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery
Status: RECRUITING
Conditions: Pain Management
Interventions: OTHER: 1.Baseline Measurements Before Surgery|OTHER: 2.Intraoperative Anesthetic Management|OTHER: 3.Postoperative Analgesic Management|OTHER: 4.Postoperative NRS Pain Assessment|OTHER: 5.Postoperative Global Rating Scale (GRS) Pain Assessment|OTHER: 6.Postoperative Patient Acceptable Symptom State (PASS) Assessment for Pain|OTHER: 7.Postoperative Quality of Recovery Assessment|OTHER: 8.Other Postoperative Assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Ascending Dose Study To Assess The Safety Profile Of SAR113244 Versus Placebo In Lupus Male And Female Patients
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: SAR113244|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms by Site
Interventions: BIOLOGICAL: Relatlimab|BIOLOGICAL: Nivolumab|BIOLOGICAL: BMS-986213
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
Status: RECRUITING
Conditions: Facet Joints; Degeneration|Back Pain|Facet Joint Pain
Interventions: DRUG: Alocyte low dose|DRUG: Alocyte medium dose|DRUG: Alocyte high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 2-year Clinical Performance of Two Different Ion-releasing Bulk-fill Restorative Materials Posterior Cavities
Status: COMPLETED
Conditions: Secondary Caries
Interventions: OTHER: Surefil One|OTHER: Cention N|OTHER: Bulkfil resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Enbrel (etanercept)|DRUG: SB4 (proposed biosimilar to etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT