pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lispro Mid Mixture (MM) Intensive Mixture Therapy With Progressive Dose-Titration of Lispro Low Mixture (LM) or Biphasic Insulin Aspart 30/70 (S019)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Biphasic Aspart 30/70|DRUG: insulin lispro LM|DRUG: insulin lispro MM|DRUG: insulin lispro LM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: HD-tCES|DEVICE: Sham HD-tCES|OTHER: Upper extremity rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC
Status: RECRUITING
Conditions: BCLC Stage C Hepatocellular Carcinoma|Chemotherapy Effect
Interventions: DRUG: intravenous FOLFOX7 plus Camrelizumab and apatinib|DRUG: HAIC-FOLFOX plus Camrelizumab and apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Walking Exercise on Functional Capacity and Productivity in Patients After Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Coronary Artery Bypass|Cardiac Rehabilitation
Interventions: BEHAVIORAL: Walking Exercise and Leg Straightening|BEHAVIORAL: Leg Straightening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Interaction and Regulation Mechanism of Different Exercise Patterns With Metabolic Syndrome and Related Metabolic Diseases
Status: RECRUITING
Conditions: Obesity|Metabolic Syndrome
Interventions: BEHAVIORAL: Low intensity exercise training|BEHAVIORAL: Moderate intensity exercise training|BEHAVIORAL: Intermittent high intensity exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of EyeArt as an Automated Diabetic Retinopathy Screening Tool
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetic Eye Problems|Diabetic Macular Edema
Interventions: PROCEDURE: Color fundus photography|DRUG: Mydriatic Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist)
Status: COMPLETED
Conditions: Emphysema
Interventions: DRUG: Placebo|DRUG: RAR Gamma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Controlled-Release Tablets 600 mg in Comparison to the Reference Standard Ibuprofen Tablets in Normal Healthy Volunteers
Status: TERMINATED
Conditions: Pain Control
Interventions: DRUG: Advil Ibuprofen table 200 mg|DRUG: Motrin IB Ibuprofen Tablets 200 mg|DRUG: Ibuprofen CR Tablets 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Therapy of Laryngeal Papilloma In Children
Status: TERMINATED
Conditions: Papilloma
Interventions: DIETARY_SUPPLEMENT: diindolylmethane (DIM)|DEVICE: 585 nm pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE)
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Obinutuzumab|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Clascoterone Cream 1% in Skin of Color Patients With Acne
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Winlevi (clascoterone) 1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of 2-octyl-cyanoacrylate (Dermabond®) in Closing Surgical Incisions in Children Before Acquisition of Continence
Status: COMPLETED
Conditions: Inguinal Incisions
Interventions: DEVICE: cutaneous suture (Surjet)|DEVICE: 2-octyl-cyanoacrylate (Dermabond® glue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-R
Status: COMPLETED
Conditions: Essential Hypertension Complicated by Type 2 Diabetes Mellitus
Interventions: DRUG: Azilsartan|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of ABBV-105 Alone or in Combination With Upadacitinib (ABBV-599 Combination) in Participants With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: Elsubrutinib|DRUG: Upadacitinib|DRUG: Placebo for elsubrutinib|DRUG: Placebo for upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterizing Psychological Consequences of Childhood Trauma
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: DEX-CRF stimulation test|BEHAVIORAL: Psychosocial stress induction|PROCEDURE: Brain imaging of sad mood , self-reference, reward|BEHAVIORAL: Acoustic startle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Halobetasol Propionate and Tazarotene Lotion (Duobrii®) for Palmoplantar Plaque Type Psoriasis
Status: COMPLETED
Conditions: Palmoplantar Psoriasis|Plaque Psoriasis
Interventions: DRUG: Duobrii®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Structured Weight Loss Program in Overweight Women With a History of Recurrent Pregnancy Loss
Status: TERMINATED
Conditions: Obese|Overweight|Miscarriage|Recurrent Pregnancy Loss
Interventions: BEHAVIORAL: Structured Weight Loss Program|BEHAVIORAL: Routine Weight Loss Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protection of Rectum From High Radiation Doses Using a Spacer
Status: TERMINATED
Conditions: Prostatic Neoplasms|Genital Neoplasms, Male|Urogenital Neoplasms|Neoplasms by Site
Interventions: DEVICE: Diluted spacer|DEVICE: Non-diluted spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Hypercapnia After Aneurysmal Subarachnoid Hemorrhage - Optimum Duration of Hypercapnia
Status: COMPLETED
Conditions: Vasospasm Intracranial
Interventions: PROCEDURE: Temporary hypercapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Intranasal Esketamine|DRUG: Intravenous Esketamine|DRUG: Moxifloxacin|DRUG: Oral Placebo|DRUG: Intravenous Placebo|DRUG: Intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Graston Assisted Soft Tissue Mobilization in Patients With Chronic Plantar Fasciitis.
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: Exercise + Graston.|OTHER: exercise only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Socket Cooling Effectiveness Take Home Study
Status: COMPLETED
Conditions: Amputation|Amputation; Traumatic, Leg, Lower|Amputation Stump|Limb; Absence, Congenital, Lower|Prosthesis User|Lower Limb Amputation Below Knee (Injury)
Interventions: DEVICE: ICE Condition|DEVICE: Sham Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study
Status: NOT_YET_RECRUITING
Conditions: Hormone-receptor-positive Breast Cancer|Premenopausal Breast Cancer|Breast Cancer Patients at Intermediate to High Risk|Ovarian Function Suppression Combined With Aromatase Inhibitor or Tamoxifen or Torimefen
Interventions: DRUG: Aromatase inhibitor|PROCEDURE: ovarian function suppression (Oophorectomy, Ovarian irradiation, Gonadotropin-releasing hormone agonist)|DRUG: Tamoxifen|DRUG: toremifene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Cemiplimab|BIOLOGICAL: ISA101b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Evening Snacks and Pre-Breakfast Intake on Sleep, Heart Rate Variability, and Stress Markers in Healthy Males.
Status: RECRUITING
Conditions: Circadian Rhythm
Interventions: DIETARY_SUPPLEMENT: Post dinner snack|DIETARY_SUPPLEMENT: Pre-Breakfast-1|DIETARY_SUPPLEMENT: Pre-Breakfast-2|DIETARY_SUPPLEMENT: Pre-Breakfast-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Doxazosin and Nifedipine on Blood Pressure Variability and Uric Acid in Plasma in Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Doxazosin|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Gel Anti-Fungal Agent for Tinea Unguium
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Organogel of naftifine, 2%|DRUG: Organogel of terbinafine, 2%|DRUG: Organogel of naftifine, 6%|DRUG: Organogel of terbinafine, 6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: (2R,6R)-Hydroxynorketamine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wheeze and Intermittent Treatment
Status: COMPLETED
Conditions: Wheezing
Interventions: DRUG: Mannitol|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Skin Grafts Versus Local Flaps for Facial Skin Cancer From the Patient Perspective: A Feasibility Study
Status: UNKNOWN
Conditions: Skin Cancer, Basal Cell|Skin Cancer|Skin Cancer, Non-Melanoma|Skin Cancers - Squamous Cell Carcinoma|Patient Satisfaction
Interventions: OTHER: FACE-Q patient reported outcome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vero cell-derived, trivalent, seasonal influenza vaccine|BIOLOGICAL: Placebo: Phosphate-buffered saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acceptance-commitment Therapy-based Psychoeducation for Individuals Experiencing Earthquakes
Status: ACTIVE_NOT_RECRUITING
Conditions: Violent Traumatic Event Having Been in an Earthquake (History)
Interventions: BEHAVIORAL: psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Ablation procedure staged catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)
Status: COMPLETED
Conditions: Otitis Media With Effusion in Children|Otitis Media Recurrent
Interventions: DRUG: EXE844 Sterile Otic Suspension, 0.3%|PROCEDURE: Tympanostomy Tube Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating a Proprietary Amino Acid Mixture (Enterade®)- for Maintaining Bowel Regularity in Patients With GI Toxicity From Any Combination of Therapy Including Tyrosine Kinase Inhibitors (TKI)
Status: TERMINATED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: Enterade beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Limb Unilateral Strength Training and Mirror Therapy for Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Mirror Therapy|OTHER: Cross-Education of Strengthening.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Transcranial Direct Current Stimulation (tDCS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation|BEHAVIORAL: Cognitive Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization Versus Proton Beam Radiotherapy for the Treatment of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Transarterial Chemoembolization|RADIATION: Proton Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Preparation in Frozen Embryo Transfer Cycles
Status: RECRUITING
Conditions: IVF
Interventions: DRUG: estradiol valerate and letrozole|DRUG: letrozole 2,5 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Markers of Post-Traumatic Stress Disorder (PTSD) Relapse
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Ontruzant (SB3) in Patients With HER2-positive Early Breast Cancer: An Open-Label (NeoON)
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasms|Breast Cancer Female|HER2-positive Breast Cancer
Interventions: DRUG: Ontruzant|DRUG: Chemotherapy|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CKD-397 Drug-drug Interaction Study (B)
Status: COMPLETED
Conditions: Healty Male Volunteers
Interventions: DRUG: Harnal-D Cap. 0.2mg|DRUG: Cialis Tab. 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Hysterectomy Via Vaginal Route
Status: RECRUITING
Conditions: Vaginal Hysterectomy|Postoperative Pain
Interventions: DRUG: duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Ductal Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Lenvatinib Mesylate|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety Evaluation of the EkiYou V2 Application in Patients With Diabetes Using Multiple Daily Insulin Injections (EkiYou-Study1)
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 1|Diabetes Type 2 on Insulin|Pancreatogenous Diabetes
Interventions: DEVICE: EkiYou V2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Erector Spina Plan Block in Patients With Lumbar Disc Herniation
Status: RECRUITING
Conditions: Low Back Pain
Interventions: DEVICE: Erector Spina Plan Block|OTHER: Stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatment
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Biopsy|Genetic Counselling|Genetic Markers
Interventions: PROCEDURE: Prostate MRI and Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of YY-20394 in Participants With Relapsed/Refractory Follicular Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Follicular
Interventions: DRUG: YY-20394
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Xyrem®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irritation and Sensitization Potential of Repeat Applications of Rotigotine Patch
Status: COMPLETED
Conditions: Bioequivalence - Irritation and Sensitization Potential of Transdermal Patch
Interventions: DRUG: Rotigotine Transdermal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EHP-5 in Preoperative Assessment in Women With Endometriosis
Status: UNKNOWN
Conditions: Endometriosis|Endometriosis Ovary|Endometriosis-related Pain|Quality of Life|Endometrioma|Endometriosis, Rectum
Interventions: PROCEDURE: Surgically treated women with endometriosis and confirmed diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rotavirus vs. Sucrose for Vaccine Injection Pain
Status: UNKNOWN
Conditions: Vaccination Pain Management
Interventions: DRUG: Sucrose|DRUG: Rotavirus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Antihypertensive Therapy and Sexual Dysfunction
Status: UNKNOWN
Conditions: Hypertension|Sexual Dysfunction
Interventions: DRUG: Felodipine add Irbesartan|DRUG: Felodipine add Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Relief Effect of Korean Red Ginseng
Status: COMPLETED
Conditions: Stress Relief
Interventions: DIETARY_SUPPLEMENT: Korean Red Ginseng|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax
Status: COMPLETED
Conditions: Efficacy|Malaria|Chloroquine|Vivax Malaria
Interventions: DRUG: Chloroquine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for People Living With HIV/AIDS
Status: UNKNOWN
Conditions: HIV|AIDS|Nicotine Dependence
Interventions: DRUG: Bupropion|BEHAVIORAL: Brief Counseling|BEHAVIORAL: High-magnitude prize contingency management|BEHAVIORAL: Monitored support to quit smoking|BEHAVIORAL: No additional treatment|BEHAVIORAL: Prize contingency management for abstinence|BEHAVIORAL: Low intensity prize contingency management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rogaratinib, Palbociclib y Fulvestrant in Patients With Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer Metastatic|Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: DRUG: Combination, Rogaratinib + palbociclib + fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hidradenitis Suppurativa Phase 2b Pivotal Study of Izokibep
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Izokibep|DRUG: Placebo to izokibep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIII Study of AL8326 in Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: AL8326 tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Levothyroxine Treatment on Hemodynamic and Renal Functions in Subclinical Hypothyroidism
Status: WITHDRAWN
Conditions: Subclinical hypothyroïdism
Interventions: DRUG: LEVOTHYROXINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Describing Cognitive Processing Speed Changes in Relapsing Multiple Sclerosis Subjects Treated With Ozanimod (RPC-1063)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: RPC-1063
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NK520 to Treat Pediatric Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: DRUG: NK520
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Three Different Techniques in Drainage of SRF During PPV in RRD
Status: NOT_YET_RECRUITING
Conditions: Rhegmatogenous Retinal Detachment
Interventions: PROCEDURE: Pars plana vitrectomy (PPV) and drainage of subretinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory Failure
Status: RECRUITING
Conditions: Mechanical Ventilation Complication|Hypoxemia|Acute Respiratory Distress Syndrome Due to COVID-19|COVID-19 Respiratory Infection|Pneumonia|Extracorporeal Membrane Oxygenation
Interventions: OTHER: Venovenous ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Unresectable Locally Advanced or Recurrent Metastatic Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: BL-B01D1|DRUG: PD-1 Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-Provided Care or Standard Care in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Fatigue|Nausea and Vomiting|Pain
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: fatigue assessment and management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: APG-1387 Plus Chemotherapy in Advanced Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: APG-1387 for Injection|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: PTSD|Psychiatric Illness|Prescription Drug Dependence|Addiction
Interventions: OTHER: Age & Development|OTHER: Socioeconomy|OTHER: Traumatic Events|OTHER: Psychosocial conditions|OTHER: Lifestyle|OTHER: Chronic conditions|OTHER: Somatic symptoms|OTHER: Psychological symptoms|OTHER: Non-prescription analgesics|OTHER: Prescription drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesh-Reduced Sling For Treating Stress Urinary Incontinence, Efficacy and Durability Trial
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Mesh-reduced Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PA Moves Trial - Patient Participants
Status: ENROLLING_BY_INVITATION
Conditions: Overweight or Obesity|Diabetes Mellitus, Type 2|Physical Inactivity
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-in-Human Safety Study Of Laser Tissue Welding For Surtureless Laparoscopic Partial Nephrectomy
Status: WITHDRAWN
Conditions: Benign Renal Tumors|Malignant Renal Tumors
Interventions: DEVICE: Laser Tissue Welding Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Complete Pathologic Response After Neoadjuvant Chemotherapy for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: TN ER-/PR-/HER2- Breast Cancer|Triple Negative Breast Cancer|HER2-positive Breast Cancer|ERany/PRany/HER2+ Breast Cancer
Interventions: RADIATION: Standard Trimodality Breast Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: [6R] 5,10-methylenetetrahydrofolate (arfolitixorin)|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Etanercept (Qiangke®) to Treat Moderate to Severe Plaque Psoriasis
Status: UNKNOWN
Conditions: Plaque Psoriasis|Psoriasis
Interventions: BIOLOGICAL: etanercept|BIOLOGICAL: etanercept (half dose)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Imlifidase in Treatment of Antibody-Mediated Rejection in Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Imlifidase|OTHER: Plasma Exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Wearable Cardioverter Defibrillator in Tachycardia Induced Cardiomyopathy
Status: UNKNOWN
Conditions: Tachycardia-induced Cardiomyopathy
Interventions: DEVICE: Life Vest Wearable defibrilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Metformin|RADIATION: Stereotactic Body Radiation Therapy (SBRT) 30 Gray (Gy)|RADIATION: Stereotactic Body Radiation Therapy (SBRT) 36 Gy|RADIATION: Stereotactic Body Radiation Therapy (SBRT) 25 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intracoronary Adult Human Mesenchymal Stem Cells After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Mesenchymal stem cell|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition for Asthmatics
Status: RECRUITING
Conditions: Asthma
Interventions: OTHER: DGA Diet|OTHER: MCT Diet|OTHER: KETO Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)
Status: COMPLETED
Conditions: Spinal Cord Injury|Cervical Spondylosis With Myelopathy|Degenerative Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: OTHER: Small amplitude (Grade IV) mobilization|OTHER: High velocity, low amplitude (Grade V) mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study to Evaluate Efficacy of Paliperidone Extended-Release(ER) in Schizophrenic Participants
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Resectable
Interventions: DRUG: Oxaliplatin|DRUG: Doxorubicin|DRUG: Lobaplatin|DRUG: Cisplatin|DRUG: Oxaliplatin, Leucovorin, fluorouracil|DRUG: Lobaplatin, Raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study
Status: RECRUITING
Conditions: Tongue Neoplasms
Interventions: PROCEDURE: removal of primary tumor, neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of BIRB 796 BS Tablets Administered to Healthy Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIRB 796 BS, low dose|DRUG: BIRB 796 BS, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Selected Disorders and Sleep Bruxism
Status: ENROLLING_BY_INVITATION
Conditions: Sleep Bruxism|Hypertension|Thyroid Dysfunction|Mental Status Change|Sleep Apnea|Sleep Disorders|Cardiovascular Risk Factor|Cardiovascular Diseases|Temporomandibular Disorder
Interventions: DRUG: Opipramol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep rTMS in Central Neuropathic Pain Syndromes
Status: COMPLETED
Conditions: Pain|Spinal Cord Injury|Post Stroke Pain
Interventions: DEVICE: deep rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
Status: RECRUITING
Conditions: Depression Minor
Interventions: DEVICE: Theta-burst stimulation (TBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of ACBT and Blow Bottle Technique in Patients With Abdominal Surgeries Under General Anesthesia
Status: RECRUITING
Conditions: Abdominal Surgery
Interventions: OTHER: Active cycle of breathing technique|OTHER: Blow Bottle Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Tislelizumab Versus Chemotherapy in Advanced Non-Squamous NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab,Cisplatin or Carboplatin ,Pemetrexed|DRUG: Cisplatin or Carboplatin,Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of Intraperitoneal Chemotherapy for Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Uterine Cancer
Interventions: DRUG: Paclitaxel, Cisplatin IP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Bacteria That Cause Tooth Decay
Status: COMPLETED
Conditions: Caries, Dental|Cariostatic Agents
Interventions: DRUG: Iodine (Betadine)|BIOLOGICAL: NaOCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lifestyle Physical Activity and Cognitive Training Interventions
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Decline|Cardiovascular Diseases|Cognitive Dysfunction|Cognitive Impairment|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Mind|BEHAVIORAL: Move
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgery Versus PhysiothErapist-leD Exercise for Traumatic Tears of the Rotator Cuff
Status: WITHDRAWN
Conditions: Traumatic Rotator Cuff Tear
Interventions: OTHER: Physiotherapist-led exercise|PROCEDURE: Surgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Increasing Physical Activity in Canadian Adults Affected by COVID-19 Social Distancing Restrictions: A Feasibility Trial of an Online Intervention"
Status: COMPLETED
Conditions: Physical Activity, Healthy Promotion
Interventions: BEHAVIORAL: Digital Health Online Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tumor Cell Vaccine in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon gamma|BIOLOGICAL: tumor cell lysate vaccine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexamethasone Added to Bupivacain in Nasal Surgery
Status: COMPLETED
Conditions: Nasal Surgery
Interventions: DRUG: Bupivacaine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a New and a Commercial Alprazolam Sublingual Formulation
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: alprazolam commercial sublingual formulation|DRUG: alprazolam test sublingual tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Serotonin in Acute and Subacute MDMA Effects
Status: COMPLETED
Conditions: MDMA Mechanism of Action
Interventions: DRUG: MDMA and citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The TOTOM Trial: Tai Chi to Optimize Transplant Outcomes for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Stem Cell Transplant Complications
Interventions: OTHER: Tai Chi Easy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Transcutaneous Tibial Nerve Stimulation and Drug Treatment' Effects in Women With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Overactive Bladder Syndrome
Interventions: DRUG: Oral Solifenacin 5mg|DEVICE: Transcutaneous Posterior Tibial Nerve Stimulation (TTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
Status: RECRUITING
Conditions: Functional Constipation (FC)|Chronic Idiopathic Constipation (CIC)
Interventions: DRUG: Linaclotide|DRUG: Placebo for Linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and CBT-1(Registered Trademark) to Treat Solid Tumors
Status: COMPLETED
Conditions: Cervical|Ovarian|Lung|Breast|Renal
Interventions: DRUG: paclitaxel|DRUG: CBT-1(Registered Trademark)|RADIATION: Tc 99m sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Synbiotic L. Fermentum Strains on Body Fat Mass
Status: UNKNOWN
Conditions: Weight, Body
Interventions: DIETARY_SUPPLEMENT: synbiotic|DIETARY_SUPPLEMENT: probiotic|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I-CBT Tailored to Patients With Cardiovascular Disease and Insomnia
Status: COMPLETED
Conditions: Insomnia|Cardiovascular Diseases
Interventions: BEHAVIORAL: Internet-based cognitive behavioral therapy for insomnia|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalation Study of MDX-010 Administered Monthly as Immunotherapy in Subjects Infected With Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: BIOLOGICAL: MDX-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of GSK Biologicals' Reduced Antigen Diphtheria and Tetanus Toxoids and Acellular Pertussis- Inactivated Poliovirus Vaccine, to BoostrixTM and Inactivated Poliovirus Vaccine Administered Separately and With Revaxis®
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Acellular Pertussis
Interventions: BIOLOGICAL: GSK Biologicals' reduced antigen diphtheria and tetanus toxoids and acellular pertussis- inactivated poliovirus vaccine|BIOLOGICAL: Boostrix™|BIOLOGICAL: GSK Biologicals' IPV vaccine|BIOLOGICAL: Revaxis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE
Status: COMPLETED
Conditions: Sarcopenic Obesity|Frailty|Malnutrition; Protein
Interventions: DIETARY_SUPPLEMENT: AA-1|DIETARY_SUPPLEMENT: AA-2|BEHAVIORAL: Placebo|BEHAVIORAL: Exe-H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Alveolar Bone Marrow Mesenchymal Stem Cells for the Reconstruction of Infrabony Periodontal Defects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: BIOLOGICAL: BM-MSCs/fibrin glue/collagen fleece|OTHER: Fibrin glue/collagen fleece|PROCEDURE: Open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Bright Light Therapy in Seasonal Affective Disorder (SAD)
Status: COMPLETED
Conditions: Seasonal Affective Disorder (SAD)
Interventions: DEVICE: Transcranial bright light therapy|DEVICE: Transcranial placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMIOdarone vs. Catheter Ablation for Prevention of Recurrent Symptomatic Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
Status: RECRUITING
Conditions: Infertility, Male|Cancer|Autoimmune Disorder
Interventions: PROCEDURE: Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study to Evaluate Efficacy and Safety of Candesartan vs Losartan in Hypertension With Heart Failure (HONOR)
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Candemore tablet|DRUG: Cozzar tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Amiloride and Spironolactone on Renophysiological and Cardiovascular Variables
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Spironolactone|OTHER: Placebo|DRUG: Amiloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Photographs of Patients on Oral Hygiene Motivation
Status: COMPLETED
Conditions: Periodontal Diseases|Motivation|Hygiene
Interventions: BEHAVIORAL: Oral hygiene motivation with individual oral photograps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of T6 Dermatome Electrical Stimulation on Gastroduodenal Motility in Healthy Volunteers
Status: TERMINATED
Conditions: Weight Loss
Interventions: DEVICE: Elira Investigational TENS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Efficacy and Safety of Vardenafil in Subjects With Erectile Dysfunction and Hypertension
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Bitter Melon on Cardiometabolic Health
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Low-dose bitter melon|DIETARY_SUPPLEMENT: High-dose bitter melon|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION