pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Immersive Virtual Reality Mindfulness Application on Quality of Life, Anxiety and Depression Symptoms in Children With Severe Tinnitus and Misophonia - A Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Tinnitus|Misophonia
Interventions: OTHER: Aurora Mindfulness app versus sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Topical Hyaluronic Acid Gel on Postoperative Pain and Wound Healing
Status: RECRUITING
Conditions: Palatal Wound
Interventions: DEVICE: Hyaluronic acid|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulsed-field Ablation vs. Sham Ablation to Treat AF
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulsed-field ablation|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics/Pharmacodynamics of HSK3486
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tri Calcium Phosphate on Efficacy and Sensitivity With Vital Tooth Whitening Using 20% Carbamide Peroxide
Status: COMPLETED
Conditions: Tooth Sensitivity
Interventions: OTHER: Tri-calcium Phosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Antibiotics for Breast Implants
Status: RECRUITING
Conditions: Implant Complication|Implant Infection|Implant Site Infection|Implant Capsular Contracture|Implant Site Pocket Infection|Implant Expulsion|Antibiotic Side Effect
Interventions: DRUG: Gentamicin, Cefazolin and Vancomycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Extraocular Extension Melanoma|Iris Melanoma|Uveal Melanoma|Recurrent Intraocular Melanoma|Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirtogenol and Bimatoprost on IOP in Hispanics With Open-Angle Glaucoma
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DIETARY_SUPPLEMENT: Experimental: Oral Mirtogenol|DIETARY_SUPPLEMENT: Placebo of oral Dietary supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptability of a Fixed Combination of Fenofibrate and Metformin
Status: COMPLETED
Conditions: Dyslipidemia/Glucose Metabolism Disorder
Interventions: DRUG: fenofibrate and metformin fixed combination (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Pharmacokinetics of a Single Oral Dose of EDP-788
Status: COMPLETED
Conditions: Safety in Normal Volunteers
Interventions: DRUG: EDP-788|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neck Posturing in Surgeons During Microsurgery Procedures Using Upright Go 2 Device
Status: NOT_YET_RECRUITING
Conditions: Neck Pain Musculoskeletal
Interventions: DEVICE: Real-time feedback through the device. Bio-feedback signals will be given once deviated from a neutral posture for >1 minute. Response of surgeons to bio-feedback signals will be recorded
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Remimazolam for Postoperative Sedation on the Left Ventricular Systolic Performance in Cardiac Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Remimazolam Injection [Byfavo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: TC-N201 cells|DRUG: IL-2|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma
Status: COMPLETED
Conditions: Brain Tumors|Central Nervous System Tumors
Interventions: DRUG: cyclosporine|DRUG: etoposide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Low-fat Diet Combined With Moderate-intensity Aerobic Exercise Versus Low-fat Diet, Aerobic Exercise Alone on Dyslipidemia and Depression Status in Obese Patients
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: OTHER: Moderate-intensity aerobic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin or Epirubicin and Cyclophosphamide in Treating Older Women With Invasive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|GENETIC: proteomic profiling|OTHER: diagnostic laboratory biomarker analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry|OTHER: pharmacological study|OTHER: surface-enhanced laser desorption/ionization-time of flight mass spectrometry|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Urea Breath Test (UBT) With Breath Hp System /BreathID Hp Lab System Pediatrics
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DEVICE: BreathID® Hp System|DRUG: BreathID® Hp Lab System|DIAGNOSTIC_TEST: Stool Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Perioperative Steroid Dosing on the APR in AIS
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis (AIS)
Interventions: DRUG: Dexamethasone postoperative|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dose Titration of LY2189265 in Overweight Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: LY2189265|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S9910, Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: OTHER: biologic sample preservation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Norethindrone/Ethinyl Estradiol 0.4 mg/35 Mcg Chewable Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Norethindrone/Ethinyl Estradiol|DRUG: Ovcon® 35 Fe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Serum Interleukin 6 and 8 in Children With Acute Gastroenteritis
Status: UNKNOWN
Conditions: Acute Gastroenteritis|Acute Diarrhea
Interventions: DIAGNOSTIC_TEST: Evaluation of serum levels of IL-6 and IL-8
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bougies as Aid for Endotracheal Intubation Via Video Laryngoscopy During Continuous Chest Compressions
Status: COMPLETED
Conditions: Endotracheal Intubation|Cardiopulmonary Resuscitation|Simulation
Interventions: DEVICE: Railroaded bougie|DEVICE: Preloaded bougie|DEVICE: Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: RMC-4630|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Strategies to Enhance Venous Thromboemboli (VTE) Prophylaxis in Hospitalized Medical Patients
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: BEHAVIORAL: Electronic Order Entry System + CDSS|BEHAVIORAL: Electronic Order Entry System Only|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
Status: UNKNOWN
Conditions: Neck Pain|Low Back Pain
Interventions: DEVICE: Muscle Pattern Recognition (MPR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Evaluation of the Efficacy and Tolerability of FASLODEX (Fulvestrant) and AROMASIN (Exemestane) in Hormone Receptor Positive Postmenopausal Women With Advanced Breast Cancer
Status: COMPLETED
Conditions: Locally Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
Status: RECRUITING
Conditions: Smoking Cessation|Smoking, Cigarette|Smoking Reduction|Smoking|Smoking, Tobacco|Quitting Smoking
Interventions: DRUG: 4 weeks of Nicotine lozenge|DRUG: 8 weeks of Nicotine Replacement Therapy Patch|BEHAVIORAL: QuitAid|BEHAVIORAL: Smokefree TXT|BEHAVIORAL: Tobacco Quitline|DRUG: 4 weeks of Nicotine Replacement Therapy Patch|DRUG: 8 Weeks Nicotine Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of a Multi-level Media Production and Social Marketing Campaign to Reduce HPV Vaccine Hesitancy
Status: RECRUITING
Conditions: Human Papillomavirus Infection|Vaccination Hesitancy
Interventions: BEHAVIORAL: PSA Development|BEHAVIORAL: HPV vaccination focused social marketing campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Status: COMPLETED
Conditions: Pulp Necroses
Interventions: OTHER: Pulpectomy using single file system ( One Shape file)|OTHER: Pulpectomy using single file system ( WaveOne Gold file)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Timing of Surgical Intervention in Buruli Ulcer Patients Treated With Antibiotics
Status: COMPLETED
Conditions: Mycobacterium Ulcerans Disease|Buruli Ulcer
Interventions: PROCEDURE: surgical intervention on Buruli ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Women and Individual Oral Prophylaxis in the Control of Gingival Inflammation (PRE-IOP)
Status: ENROLLING_BY_INVITATION
Conditions: Pregnant Woman
Interventions: DEVICE: Sonicare DiamondClean 9000 Philips®|DEVICE: HydroSonic Easy Curaden®|DEVICE: Manual toothbrush Oral-B 123|DEVICE: Manual toothbrush Curaprox CS 5460
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melanoma Checkpoint and Gut Microbiome Alteration With Microbiome Intervention
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Placebo for antibiotic|DRUG: Vancomycin pretreatment|DRUG: Nivolumab|DRUG: Matching Placebo for SER-401|DRUG: SER-401
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Divalproex Sodium in Children With ASD and Epileptiform EEG
Status: WITHDRAWN
Conditions: Autism|Autism Spectrum Disorders
Interventions: DRUG: Divalproex Sodium|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Malaria Vaccines in Kenyan Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: ChAd63 ME-TRAP / MVA ME-TRAP prime-boost immunisation|BIOLOGICAL: Rabies vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Switch Study of Existing Atypical Antipsychotics to Bifeprunox
Status: COMPLETED
Conditions: Schizophrenia and Schizoaffective Disorder
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine|DRUG: Risperidone|DRUG: Quetiapine|DRUG: Ziprasidone|DRUG: Aripiprazole|DRUG: Olanzapine|DRUG: Risperidone|DRUG: Quetiapine|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of the Effects of Vortioxetine (Lu AA21004) on Cognition and Blood Oxygen Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Signals in Subjects Remitted From Depression and in Controls
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Vortioxetine (Lu AA21004)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Tranexamic Acid Adverse Reaction
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial
Status: RECRUITING
Conditions: PROSTATE CANCER|Metastatic Prostate Cancer|Metastatic Prostate Carcinoma
Interventions: BEHAVIORAL: Supervised Circuit Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Samarium Sm 153 Lexidronam Pentasodium and 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Rising Prostate-Specific Antigen Levels After Radical Prostatectomy for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Radiotherapy|DRUG: Samarium 153
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: irinotecan|DRUG: leucovorin|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBUS-Miniforceps Biopsy Specimen Acquisition for PD-L1 Testing in Nonsmall Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|NSCLC
Interventions: DEVICE: CoreDx Pulmonary Mini-Forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors
Status: TERMINATED
Conditions: Glioma|Glioma, Malignant|Glioma, Mixed|Glial Cell Tumors|Breast Cancer|Breast Carcinoma|Cancer of Breast|Cancer of the Breast|Breast Tumor|Malignant Tumor of Breast|Advanced Breast Cancer|Advanced Breast Carcinoma|Metastatic Breast Cancer|Metastatic Breast Carcinoma|Prostate Cancer|Prostatic Cancer|Cancer of Prostate|Cancer of the Prostate|Prostate Neoplasm|Castrate Resistant Prostate Cancer|Castration-resistant Prostate Cancer|Castration Resistant Prostatic Neoplasms|Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: NUV-422
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of a Non-invasive Device in the Management of Open Abdomen (AbCLO)
Status: RECRUITING
Conditions: Open Abdomen
Interventions: DEVICE: AbCLO (Abdominal Wall Closure) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Effect on Decreasing glUcoCorticoid Exposition in PolyMyalgia Rheumatica Patients Recently Diagnosed
Status: RECRUITING
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis
Status: COMPLETED
Conditions: Tendonitis|Bursitis
Interventions: DRUG: Ketoprofen Topical Patch 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Radicle Clarity: A Study of Health and Wellness Products on Mental Clarity and Health Outcomes
Status: COMPLETED
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Clarity Active Study Product 1.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 2.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 3.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 4.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 4.2 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 4.3 Usage|DIETARY_SUPPLEMENT: Placebo Control Form 1|DIETARY_SUPPLEMENT: Placebo Control Form 2|DIETARY_SUPPLEMENT: Placebo Control Form 3|DIETARY_SUPPLEMENT: Placebo Control Form 4|DIETARY_SUPPLEMENT: Placebo Control Form 5|DIETARY_SUPPLEMENT: Clarity Active Study Product 5.1 Usage|DIETARY_SUPPLEMENT: Clarity Active Study Product 5.2 Usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects
Status: RECRUITING
Conditions: IgA Nephropathy|Focal Segmental Glomerulosclerosis
Interventions: DRUG: HS-10390 tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: temsirolimus plus liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amlodipine Freeze-Dried Powder for Oral Solution 5 mg
Status: COMPLETED
Conditions: Hypertension|Coronary Artery Disease
Interventions: DRUG: Amlodipine Freeze-Dried Powder for Oral Solution 5 mg|DRUG: Norvasc 5 mg tablets of Pfizer Labs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smoking Cessation in Patients With COPD (SMOCC) in General Practice
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Counseling and Nicotine replacement (CN)|BEHAVIORAL: Counseling, Nicotine replacement and Bupropion (CNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo supplement|DIETARY_SUPPLEMENT: Citicoline supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Trial Testing ZP1848 in Patients With SBS
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: ZP1848
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty: Multiple Blocks by UltraSound
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine|DEVICE: Ultrasound|PROCEDURE: Peripheral nerve blockade|DRUG: Saline|PROCEDURE: Total hip arthroplasty|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Predictive Model of Bowel Preparation Based on Procedure-related Factors
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation|Predictive Model
Interventions: DRUG: Polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Anti HCV Drugs in the Treatment of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine , Sofosbuvir, daclatasvir|DRUG: Standard of care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Physical and Emotional Violence by Parents and Teachers in Public Schools in Tanzania (ICC-T/ICC-P_Tanz)
Status: RECRUITING
Conditions: Violence
Interventions: BEHAVIORAL: Interaction Competencies with Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness
Status: COMPLETED
Conditions: Insomnia|Insomnia Chronic|Insomnia Due to Mental Disorder|Insomnia, Psychophysiological|Sleep Disorder|Sleep Initiation and Maintenance Disorders|Sleep Disturbance|Mental Illness|Psychological Disorder|Depression, Anxiety
Interventions: BEHAVIORAL: Cognitive behavioral therapy for insomnia (CBTi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Treatment for Refractory H Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: rabeprazole+3 antibiotics|DRUG: rabeprazole+bismuth+2 antibiotics|DRUG: rabeprazole+amox+tetr+levo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mirasol-treated Apheresis Platelets in Patients With Hypoproliferative Thrombocytopenia
Status: TERMINATED
Conditions: Hematologic Malignancies|Hypoproliferative Thrombocytopenia
Interventions: DEVICE: Mirasol platelets (MIR PLTs)|DEVICE: Reference platelets (REF PLTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-escalating Trial With Allo-RevCAR01-T Cells in Combination With CD123 Target Module (R-TM123) for Participants With Selected Hematologic Malignancies Positive for CD123
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: OTHER: Cyclophosphamide (Non-IMP, Lymphodepletion)|OTHER: Fludarabine (Non-IMP, Lymphodepletion)|DRUG: R-TM123|DRUG: Allo-RevCAR01-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DEVICE: Tourniquet|DEVICE: INVOS assessment|DEVICE: EMG assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correction of Neonatal Glutathione by N-acetylcysteine in Pregnant Women at Risk of Premature Birth (GSH MAP)
Status: TERMINATED
Conditions: Preterm Delivery
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ice Plant (Mesembryanthemum Crystallinum) Extract in Patients With Impaired Fasting Glucose
Status: COMPLETED
Conditions: Impaired Fasting Glucose
Interventions: DIETARY_SUPPLEMENT: Ice plant group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Food Effects of Herombopag Olamine Tablets in Healthy Subjects.
Status: NOT_YET_RECRUITING
Conditions: Adult Patients With Chronic Primary ITP|Adult Patients With SAA Who do Not Respond Well to Immunosuppressive Therapy
Interventions: DRUG: Herombopag Olamine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AVB-620 in Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Primary Invasive Malignant Neoplasm of Female Breast|Carcinoma Breast|Breast Cancer Female|Carcinoma, Ductal, Breast|Stage II Breast Cancer|Stage I Breast Cancer|Stage III Breast Cancer
Interventions: DEVICE: Investigational Imaging device|DRUG: AVB-620
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oxcarbazepine Monotherapy in Adults With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial Seizures
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Oral Appliance Therapy on Masseter Muscle Activity in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: mandibular advancement appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Separate and Combined Effects of Vivitrol and Opiate Abstinence Reinforcement in the Treatment of Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Vivitrol|BEHAVIORAL: Employment-based opiate abstinence reinforcement|OTHER: Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Maintenance (WLM)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Obesity|Diabetes Mellitus, Non-insulin Dependent|Hypertension
Interventions: BEHAVIORAL: Personal contact (PC)|BEHAVIORAL: Interactive technology (IT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol
Status: COMPLETED
Conditions: Asthma|Bronchoconstriction
Interventions: DRUG: Levalbuterol HFA MDI|DRUG: Racemic Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SteadiSet™ Pilot Study (SteP Study)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type I|IDDM|Diabetes Mellitus, Insulin-Dependent, 1|Type 1 Diabetes|Type 1 Diabetes Mellitus
Interventions: DEVICE: Control Device insulin infusion devcie|DEVICE: Investigative insulin infusion devcie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration|Geographic Atrophy
Interventions: DRUG: IONIS-FB-LRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of AdCLD-CoV19-1 OMI as a Booster: A COVID-19 Preventive Vaccine in Healthy Volunteers
Status: RECRUITING
Conditions: COVID-19|Vaccines
Interventions: BIOLOGICAL: AdCLD-CoV19-1 OMI|BIOLOGICAL: Comirnaty Bivalent 0.1mg/mL (tozinameran and riltozinameran)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation Study of a Device for Detecting Arteriovenous Fistula Vascular Function
Status: RECRUITING
Conditions: Arteriovenous Fistula Flow Monitoring|Early Detection of Complications of Arteriovenous Fistula|Voiceprint
Interventions: DEVICE: A device for detecting arteriovenous fistula vascular function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing the Safety and Efficacy of Fluticasone and Formoterol Combination (FlutiForm™) With Fluticasone or Flovent to Treat Moderate to Severe Asthma in Adolescents and Adults
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FlutiForm 250/10|DRUG: SKP-Fluticasone|DRUG: Flovent Fluticasone HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ocular Point of Care Ultrasound in Diagnosing Retinal Detachment in the Emergency Department
Status: COMPLETED
Conditions: Retinal Detachment
Interventions: DEVICE: Ultrasound|OTHER: Ophthalmology Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Broccoli Sprout Extract on Allergy Rhinitis
Status: COMPLETED
Conditions: Rhinitis,Allergic
Interventions: DIETARY_SUPPLEMENT: Broccoli Sprout Extract|DRUG: fluticasone nasal|DIETARY_SUPPLEMENT: broccoli sprout extract placebo|DRUG: normal saline nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Colchimax®|DRUG: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sm-p80 Schistosomiasis Challenge Study
Status: NOT_YET_RECRUITING
Conditions: Schistosoma Mansoni|Schistosomiasis
Interventions: BIOLOGICAL: Sm-p80 + GLA-SE Vaccine|OTHER: Placebo|BIOLOGICAL: Schistosoma mansoni infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DEVICE: Erchonia® FX-635™|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas.
Status: COMPLETED
Conditions: Ovarian Carcinoma|Soft Tissue Sarcoma
Interventions: DRUG: Combination of trabectedin with durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of the Colonoscope Magnetic Imaging Device (ScopeGuide®) in Patients With Implantable Cardiac Devices
Status: COMPLETED
Conditions: Cardiac Arrhythmia
Interventions: DEVICE: Exposure to ScopeGuide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Citrate and Heparin Anticoagulation During Hemodialysis With MCO PES-PVP (Theranova) Membrane
Status: UNKNOWN
Conditions: End Stage Renal Disease|Haemodialysis|Anticoagulation
Interventions: BIOLOGICAL: unfractionated heparin|BIOLOGICAL: 8% trisodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyspnea Neuroscience Education on Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Dyspnea
Interventions: BEHAVIORAL: Dyspnea Neuroscience education|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Study for INFORMED
Status: RECRUITING
Conditions: Heart Failure|Heart Failure, Diastolic|Heart Failure With Preserved Ejection Fraction|Cardiac Failure|Heart Diseases
Interventions: DRUG: Beta blocker|DRUG: Beta blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 3 Study of Acupression's Bracelets in Nausea and Vomiting Induced by FEC100 Chemotherapy's Sort.
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: Acupression's bracelet|BEHAVIORAL: Hygiene and dietetic advices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Minimally Invasive Surgical Approaches for Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Hip Osteoarthritis|Hip Arthropathy|Minimal Invasive|Anterior Approach|Tissue Injury
Interventions: PROCEDURE: Mini posterior approach Total Hip Replacement|PROCEDURE: Anterior approach total hip replacement without a traction table|PROCEDURE: Anterior approach total hip replacement with a traction table
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Craniosacral Therapy and Myofacial Relaxation Techniques in People Diagnosed With Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: OTHER: Osteopathic Manipulative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acromegaly: Balance, Falls and Fracture Risk
Status: COMPLETED
Conditions: Acromegaly
Interventions: RADIATION: HR-pQCT|RADIATION: DXA scan|DIAGNOSTIC_TEST: Bone microindentation|DIAGNOSTIC_TEST: Hand grip and leg extension strength|DIAGNOSTIC_TEST: Timed up-and-go test|DIAGNOSTIC_TEST: Stabilometry|DIAGNOSTIC_TEST: Nerve conduction test|DIAGNOSTIC_TEST: Visual acuity test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective, Comparative Study to Explore the Efficacy and Safety of the Five Channels Multiway Deep Transcranial Magnetic Stimulation (TMS) Device in Subjects With Major Depression Disorder (MDD)
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: 5 channels Multiway deep Transcranial Magnetic Stimulator|DEVICE: five channels Multiway deep Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect
Status: COMPLETED
Conditions: Breast Cancer|Leukemia|Lymphoma|Neuroblastoma|Ovarian Cancer|Sarcoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: cyclophosphamide|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volume Kinetics for Starch Solution and Acetated Ringers
Status: COMPLETED
Conditions: Blood Volume|Blood Coagulation
Interventions: DRUG: acetated Ringers|DRUG: colloid|DRUG: colloid+acetated Ringer|DEVICE: Non-invasive hemoglobin with pulse-oximeter (SpHb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy
Status: COMPLETED
Conditions: Late Infantile Metachromatic Leukodystrophy
Interventions: OTHER: High-field MRI (3 Teslas)|OTHER: High-field MRI (3 Teslas)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study of SANGUINATE™ Versus Hydroxyurea in Sickle Cell Disease (SCD) Patients
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: SANGUINATE™|DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Stress, Psychological
Interventions: DIETARY_SUPPLEMENT: Lpc-37|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicentre Trial on the Effectiveness of Physical Rehabilitation of Patients With Coronary Artery Disease: Aerobic Interval Training Versus Moderate Continuous Training.
Status: UNKNOWN
Conditions: Coronary Artery Disease (CAD);|Myocardial Infarction (MI)|Percutaneous Coronary Intervention (PCI)|Coronary Artery Bypass Grafting (CABG)
Interventions: BEHAVIORAL: Aerobic interval training|BEHAVIORAL: Moderate endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Neoadjuvant Chemotherapy With Doxorubicin Followed by Docetaxel-Cisplatin in Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin, Docetaxel, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Post-Remission Therapy in Elderly Patients With Acute Myelogenous Leukemia.
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Two post-remission strategies|DRUG: Idarubicin versus daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ectoin® Containing Eye Drops and Ectoin® Containing Eye Spray With the Eye Spray Tears Again®
Status: COMPLETED
Conditions: Eye Manifestations
Interventions: DEVICE: Ectoin® Allergy Eye Drops 2%|DEVICE: Ectoin® Eye Spray Colloidal|DEVICE: Tears Again® eye spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Radiotherapy Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of NSCLC Patients With Symptomatic Brain Metastases
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Metastatic|Brain Metastases
Interventions: RADIATION: Radiotherapy combined with PD-1 inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Online Theory-based Educational Programme for Primiparous Women on Improving Breastfeeding Related Outcomes
Status: COMPLETED
Conditions: Breastfeeding, Exclusive|Self Efficacy
Interventions: OTHER: REST intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pivotal Study of rhBMP-2/ACS/LT-CAGE® Device for Anterior Lumbar Interbody Fusion in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/ACS//LT-CAGE® Device|DEVICE: Autogenous Bone//LT-CAGE® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults
Status: COMPLETED
Conditions: Fracture|Dislocation
Interventions: DRUG: Procedural sedation with ketamine-propofol combination|DRUG: Procedural sedation with ketamine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspiration of Limited Number of Follicles to Prevent Severe Ovarian Hyperstimulation Syndrome
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: 7 eggs collection|PROCEDURE: Full eggs collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000
Status: COMPLETED
Conditions: Cataract|Macular Degeneration
Interventions: DRUG: selenium|DRUG: vitamin E|DRUG: vitamin E placebo|DRUG: selenium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A European Network for the Investigation of Gender Incongruence
Status: RECRUITING
Conditions: Physical and Psychological Evaluation of Hormonal Therapy in Transsexual Persons
Interventions: OTHER: questionnaires|BIOLOGICAL: blood sampling|OTHER: clinical evaluation|OTHER: Dermatology evaluation|OTHER: Bone evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of SYNB1934 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SYNB1934|DRUG: SYNB1618
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cannabis on Dystonia and Spasticity on Pediatric Patients
Status: UNKNOWN
Conditions: Spasticity|Dystonia
Interventions: DRUG: Avidekel oil|DRUG: Enriched Avidekel oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication With Clostridum Butyricum Capsule and Bacillus Coagulans Tablets
Status: COMPLETED
Conditions: Gastritis|H Pylori Infection|Dyspepsia
Interventions: DRUG: Clostridum Butyricum Capsule|DRUG: Bacillus Coagulans Tablets|DRUG: Clostridum Butyricum Capsule plus Bacillus Coagulans Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD4076 in Type 2 Diabetic Subjects With Non-Alcoholic Fatty Liver Disease.
Status: COMPLETED
Conditions: T2DM With NAFLD
Interventions: DRUG: AZD4076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT