pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase I Multiple Ascending Dose Study of ASLAN002 in Subjects With Advanced or Metastatic Solid Tumours
Status: COMPLETED
Conditions: Malignant Solid Tumour
Interventions: DRUG: ASLAN002( BMS 777607)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TIPS Plus Transvenous Obliteration for Gastric Varices
Status: RECRUITING
Conditions: Cirrhosis, Liver|Hypertension, Portal|Esophageal and Gastric Varices|Bleeding Gastric|Encephalopathy
Interventions: DEVICE: TIPS-obliteration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension
Status: COMPLETED
Conditions: Adult Respiratory Distress Syndrome|Pulmonary Hypertension
Interventions: DRUG: PGE1 (prostacyclin)|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Walnut Ingestion in Adults at Risk for Diabetes: Effects on Body Composition, Diet Quality, and Cardiac Risk Measures
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Walnut Ad libitum diet|DIETARY_SUPPLEMENT: Walnut Calorie controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Bone on Vibration-Induced Muscle Strength Gain
Status: COMPLETED
Conditions: Bone Mass|Effects of Vibration
Interventions: DEVICE: whole-body vibration (WBV)|DEVICE: WBV (Sham stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: regional nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of Different Combinations of Trivalent Influenza Vaccine Varying Influenza Antigen Dose, Adjuvant Dose, and Route of Administration in Healthy Elderly Individuals Ages 65 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine|BIOLOGICAL: Trivalent Influenza Vaccine + high A|BIOLOGICAL: Trivalent Influenza Vaccine + ¼ dose adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine + high A + ¼ dose adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine + ½ dose adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine + high A + ½ dose adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine + adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine + high A + adjuvant|BIOLOGICAL: Trivalent Influenza Vaccine intradermal dose|BIOLOGICAL: Trivalent Influenza Vaccine + high A intradermal dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in People With Persistent Symptoms During the Subacute Period After Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Erythropoeitin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Intermittent Pneumatic Compression Devices for Deep Vein Thrombosis
Status: COMPLETED
Conditions: Venous Thrombosis|Deep Vein Thrombosis
Interventions: DEVICE: DVT-3000|DEVICE: SCD Express
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Desloratadine 5 mg|DRUG: Aprepitant 125 mg|DRUG: Ketotifen 1 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy Children|Children With Traumatic Brain Injury|Mental Handicap|Delayed Speech Development
Interventions: DRUG: Cerebrolysin (Nerve growth factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Early Cognitive Behavioral Therapy With or Without Parental Involvement in Treating Anxious Children
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Group CBT for children|BEHAVIORAL: Group CBT for children plus parent training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Troxatyl™ (troxacitabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life After Bladder-Preservation Chemotherapy and Radiation Therapy in Patients With Muscle-Invasive Bladder Cancer
Status: WITHDRAWN
Conditions: Infiltrating Bladder Urothelial Carcinoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sugammadex and Brain Waves
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Sugammadex|DRUG: Neostigmine and glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality and Music During Circumcision in Children
Status: COMPLETED
Conditions: Fear|Anxiety|Child
Interventions: OTHER: Immersive virtual reality group|OTHER: Music group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lung Ultrasound Guided Prevention of Postoperative Pulmonary Complications in Moderate to High Risk Patients
Status: UNKNOWN
Conditions: Postoperative Respiratory Complication
Interventions: OTHER: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Online Imaginal Exposure
Status: COMPLETED
Conditions: Eating Disorder|Exposure|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder|Therapy
Interventions: BEHAVIORAL: Imaginal Exposure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome
Status: WITHDRAWN
Conditions: Short Bowel Syndrome
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Muscle Protein Breakdown in the Regulation of Muscle Quality in Frail Elderly Individuals
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Strength training|DIETARY_SUPPLEMENT: Protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer|ER-positive Breast Cancer|HER2-negative Breast Cancer|ESR1 Gene Mutation
Interventions: DRUG: Everolimus|DRUG: Elacestrant|DRUG: Placebo|DRUG: Auxiliary Medicinal Product - Dexamethasone|DRUG: Auxiliary Medicinal Product - Luteinizing hormone-releasing hormone (LHRH) analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silicone Sock as Treatment of Deep Heel Fissures in People With Diabetes
Status: UNKNOWN
Conditions: Diabetes Complications
Interventions: DEVICE: Sock of silicone|OTHER: Heel cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CoMind Early Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Intracranial Pressure|Intracranial Pressure Changes|Traumatic Brain Injury|Intracerebral Hemorrhage|Encephalitis|Encephalopathy|Hydrocephalus|Stroke|Autoregulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy
Status: RECRUITING
Conditions: HCC - Hepatocellular Carcinoma|Metastatic Cancer|Metastatic Tumor
Interventions: DRUG: Ipilimumab Injection|DRUG: Atezolizumab Injection|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone in Luteal Phase Deficiency
Status: WITHDRAWN
Conditions: Luteal Phase Defect
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacist-led Inpatient Anticoagulation Stewardship Program
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Atrial Fibrillation|Mitral Valve Disease
Interventions: OTHER: Anticoagulation Stewardship Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rehabilitation After Radiotherapy for Prostate Cancer
Status: COMPLETED
Conditions: Urinary Irritative/Incontinence Problems|Bowel Problems|Sexual Problems|Hormonal Problems|Phycological Problems
Interventions: BEHAVIORAL: RePCa A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Modification in Complementary Food Composition to Improve the Status of Iron and Fatty Acids in Infants.
Status: COMPLETED
Conditions: Iron Status|Fatty Acid Status
Interventions: OTHER: more meat and a vegetable oil rich in omega-3 fatty acids|OTHER: Babyfood with usual meat content and corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Nausea and Vomiting|Precancerous Condition|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: ondansetron|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PeriOperative ISchemic Evaluation-3 Trial: A Pilot Study
Status: COMPLETED
Conditions: Atherosclerotic Disease|Perioperative Bleeding
Interventions: DRUG: Tranexamic Acid|DRUG: Tranexamic Acid Placebo|DRUG: Rosuvastatin or matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: ADMVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel and Ganetespib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer
Interventions: DRUG: paclitaxel|DRUG: ganetespib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Imaging of Cetuximab-Zr. 89 Uptake Wit PET: a Phase I Trial in Stage IV Cancer Patients
Status: COMPLETED
Conditions: Stage IV Cancer
Interventions: DRUG: Cetuximab-Zr. 89
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment With Atomoxetine Hydrochloride in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder|Comorbid Dyslexia
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided cTBS at Different Doses for Aphasia After Stroke
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: active 1200-pulse continuous Theta Burst Stimulation|DEVICE: active 2400-pulse continuous Theta Burst Stimulation|DEVICE: active 3600-pulse continuous Theta Burst Stimulation|DEVICE: sham 1200-pulse continuous Theta Burst Stimulation|DEVICE: sham 2400-pulse continuous Theta Burst Stimulation|DEVICE: sham 3600-pulse continuous Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patientheque in Patients With a Psychosis .
Status: RECRUITING
Conditions: Schizophrenia Prodromal|Schizophrenia, Childhood|Schizophrenia
Interventions: OTHER: Blood samples (36 mL) + fecal samples + hair sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pediatric Trial Investigating the Incidence & Outcome of Veno-Occlusive Disease With the Prophylactic Use of Defibrotide
Status: COMPLETED
Conditions: Hepatic Veno-Occlusive Disease
Interventions: DRUG: Defibrotide|DRUG: Defibrotide|DRUG: Defibrotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Timing of Direct Current Cardioversion (DCC) in Patients Undergoing Ablation of Persistent/Permanent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: DCC first then PVI|PROCEDURE: PVI then DCC after
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bipolar Efficacy Biomarkers for rTMS
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar Disorder|Bipolar Depression
Interventions: DEVICE: Accelerated Theta Burst Stimulation|DEVICE: Sham accelerated Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study
Status: UNKNOWN
Conditions: Diminished Ovarian Reserve|Premature Ovarian Insufficiency|Fertility Issues|IVF
Interventions: PROCEDURE: Autologous Platelet-rich Plasma (PRP) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabis and Schizophrenia: Self-Medication and Agonist Treatment
Status: COMPLETED
Conditions: Schizophrenia|Dual Diagnosis|Schizoaffective Disorder|Psychotic Disorder|Cannabis Use Disorder
Interventions: DRUG: Dronabinol|DRUG: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence Cirrhosis of the Liver on the Coronary Re-stenosis (LTX- Stent Study)
Status: WITHDRAWN
Conditions: Re-stenosis|Cirrhosis of the Liver
Interventions: DEVICE: ZES|DEVICE: BMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic and Comparative Bioavailability Study of Testosterone Absorption After Administration of Testosterone Gel 1.62% to the Upper Arms/Shoulders Using an Application Site Rotation or a Combination of Application Sites in Hypogonadal Males
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone Gel 1.62%|DRUG: Testosterone Gel 1.62%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Series Studies of Bipolar Disorder-Valproate add-on Memantine
Status: COMPLETED
Conditions: Bipolar Disorders
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Psyllium on Niacin Tolerability
Status: COMPLETED
Conditions: Flushing|Hyperlipidemias|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Psyllium|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Trial of Procrit vs. No Procrit in AML and High Risk MDS
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Leukemia
Interventions: DRUG: Procrit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Global Effects of a Probiotic Strain on Lactating Women
Status: COMPLETED
Conditions: Mastitis
Interventions: BIOLOGICAL: Lactobacillus salivarius PS2|BIOLOGICAL: Lactobacillus salivarius PS2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: SARS-CoV-2 Bivalent mRNA Vaccine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dehydroepiandrosterone (DHEA) on Hot Flashes in Postmenopausal Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Placebos|DRUG: DHEA capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Topical Pomegranate Extracts in Management of Oral Lichen Planus (A Randomized Clinical Trial)
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Topical pomegranate seeds and peel extracts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Lung Non-Small Cell Squamous Carcinoma|Lung Non-Squamous Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Gemcitabine Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|OTHER: Observation|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed Disodium|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralymphatic Immunotherapy Enhanced by Vitamin-D, a Randomized Placebo-controlled Trial and Comparison With SLIT
Status: RECRUITING
Conditions: Allergic Rhinitis Due to Grass Pollen
Interventions: DRUG: SLIT Grazax ALK Nordic 75 000 SQ-T|DRUG: ILIT + Vitamin D|DRUG: ILIT + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With or Without Vismodegib in Treating Metastatic or Unresectable Basal Cell Skin Cancer
Status: COMPLETED
Conditions: Skin Basal Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry
Status: RECRUITING
Conditions: Mitral Valve Regurgitation|Mitral Valve Stenosis|Tricuspid Valve Regurgitation
Interventions: DEVICE: edge-to-edge valve repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aerobic Training With and Without Resistance Training in Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Aerobic Exercise|OTHER: Aerobic Exercises with Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tooth Erosion in People With Esophagogastric Cancer
Status: RECRUITING
Conditions: Esophagogastric Cancer
Interventions: OTHER: Survey|OTHER: Intra-oral camera|OTHER: Optional Salvia sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double-Dose Safety Study of An Influenza Vaccine (Multimeric-001)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Adjuvanted Multimeric-001 250 Mcg|BIOLOGICAL: Multimeric-001 250 Mcg|BIOLOGICAL: Phosphate Buffered saline|BIOLOGICAL: Adjuvanted PBS|BIOLOGICAL: Adjuvanted Multimeric-001 500 Mcg|BIOLOGICAL: Multimeric-001 500 Mcg|BIOLOGICAL: Multimeric-001 125 Mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Exhaled Nitric Oxide : Biomarker of Acute Respiratory Distress Syndrome
Status: NOT_YET_RECRUITING
Conditions: ARDS, Human|Nitric Oxyde
Interventions: OTHER: Non invasive measure of endogenous exhaled Nitric Oxyde in exhaled gaz, by a laser spectrometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Tasty&Healthy" Dietary Approach for Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Tasty&Healthy intervention group|DIETARY_SUPPLEMENT: EEN intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis Type 1
Interventions: DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Breast Carcinoma|Recurrent Breast Carcinoma|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: Utomilumab|DRUG: Trastuzumab|DRUG: Ado-Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Virtual Reality Mindfulness in Patients With Psychosis
Status: COMPLETED
Conditions: Schizophrenia Spectrum Disorders|Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders|Psychotic Disorder Not Otherwise Specified
Interventions: OTHER: Virtual Reality Mindfulness Treatment|OTHER: Experience relaxing scenery and music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of an Antimicrobial Stewardship (AMS) Program, on the Prevalence of Multidrug-resistant Gram - Negative Pathogens, in an Area of High Consumption of Antibiotics and High Resistance Rates
Status: UNKNOWN
Conditions: Antimicrobial Stewardship Program
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EUS Guided Drainage of Post Pancreatitis Pancreatic Fluid Collection
Status: NOT_YET_RECRUITING
Conditions: Pancreas Pseudocyst
Interventions: PROCEDURE: Endoscopic ultrasound guided cystogastrostomy of symptomatic pancreatic pseudocyst
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Fluid Wash in Pre-labour Rupture of Membranes
Status: UNKNOWN
Conditions: Disorder of Amniotic Cavity and/or Membrane
Interventions: PROCEDURE: Urea and creatinine|PROCEDURE: Nitrazine|DRUG: 5ml saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: 3BNC117 and 10-1074 in ART-treated Individuals
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: 3BNC117|DRUG: 10-1074|OTHER: Analytical treatment interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety of KBL697 in Patients With Mild to Moderate Active Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: KBL697|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis (Diagnosis)|Nasal Polyps|Asthma|Obstructive Sleep Apnea|Airway Disease|Inflammatory Disease|Concomitant Disease
Interventions: DIAGNOSTIC_TEST: Fractioned Exhaled Nitrogen Oxide measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Different Minimal Invasive Treatment Modalities of Mild to Moderate Dental Fluorosis Using A Visual Analog Scale
Status: COMPLETED
Conditions: Dental Fluorosis
Interventions: OTHER: Opalescence™ boost™ PF 40%|OTHER: Opalustre™|OTHER: MI-Paste Plus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Tolerability of a Novel Hydration Drink in Healthy Volunteers
Status: COMPLETED
Conditions: Tolerance
Interventions: OTHER: 1 serving of test product|OTHER: 2 servings of test product|OTHER: 3 servings of test product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Test Genetic Alterations Among Different Dermoscopic Types of Melanocytic Nevi.
Status: COMPLETED
Conditions: Nevi
Interventions: GENETIC: To test the frequency of BRAF and NRAS mutations among nevi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Combining Topical Antibiotic/Steroid/Moisturizer Therapy Compared to Active Comparator in Atopic Dermatitis.
Status: UNKNOWN
Conditions: Severe Atopic Dermatitis
Interventions: OTHER: Polyethylene glycol hexadecyl ether & Betamethasone valerate cream 0.1%|OTHER: Fusidic acid, polyethylene glycol hexadecyl ether & Betamethasone valerate cream 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab in STK11 Mutated NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer With STK11/LKB1 Mutation
Interventions: DRUG: Daratumumab and Hyaluronidase-fihj|DRUG: Pre-Intervention Medication|DRUG: Post-Intervention Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The China Longitudinal Aging Study of Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Dementia, Vascular|Dementia With Lewy Bodies|Dementia Frontal|Depression|Anxiety
Interventions: OTHER: Naturalistic observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Who Are Scheduled for Laser Epithelial Keratomileusis (LASEK) Surgery
Status: RECRUITING
Conditions: Dry Eye Disease
Interventions: DEVICE: Charge-Balanced, Symmetric Nerve Stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Reduction of the Balloon Volume for Prevention of Postoperative Catheter-related Bladder Discomfort in Patients Undergoing Non-lower Urinary Tract Surgery
Status: NOT_YET_RECRUITING
Conditions: Catheter-Related Bladder Discomfort|Urinary Catheter
Interventions: PROCEDURE: Urinary catheter balloon size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase II Clinical Trial of Clenbuterol in Adult Patients With Pompe Disease
Status: WITHDRAWN
Conditions: Pompe Disease (Late-onset)
Interventions: DRUG: Clenbuterol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Smoking Cessation BUndle in a Tertiary Care Hospital - Can Turning Virtual Improve Outcomes?
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation|Surgical Complications
Interventions: OTHER: Remote smoking cessation bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multimodal Investigation in the Diagnosis and Treatment of Chronic Adult Hydrocephalus
Status: COMPLETED
Conditions: Chronic Adult Hydrocephalus
Interventions: OTHER: Diagnosis of ICAH using new investigative techniques (computerised gait analysis, ultrasound, MRI flow, urinary incontinence scale)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Panitumumab, Cisplatin, and Pelvic Radiation Therapy in Treating Patients With Stage IB, Stage II, or Stage III Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: cisplatin|RADIATION: brachytherapy|RADIATION: external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hypertonic Saline for Infants Hospitalized With Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: 3% sodium chloride|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: DRUG: orvepitant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Nifedipine Versus IV Labetalol in Severe Pre Eclampsia
Status: UNKNOWN
Conditions: Severe Pre-Eclampsia, Antepartum
Interventions: DRUG: Nifedipine 10 mg|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MHealth Intervention of HIV and STDs Partner Notification for MSM
Status: UNKNOWN
Conditions: HIV/AIDS|Sexually Transmitted Diseases|Prevention
Interventions: BEHAVIORAL: Health education, and regular HIV and STDs testing prompting service|BEHAVIORAL: Health status inquiry through app (partner notification)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Fevipiprant (QAW039) in Patients With Hepatic Impairment Compared to Matched Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Fevipiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of HTD4010 in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HTD4010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Steroids for Peripheral Nerve Blocks
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine|DRUG: Epinephrine|PROCEDURE: Saphenous Peripheral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Far Cortical Locking Versus Standard Constructs for Distal Femur Fractures
Status: ACTIVE_NOT_RECRUITING
Conditions: Distal Femur Fracture
Interventions: DEVICE: Far Cortical locking screw fixation|DEVICE: Standard screw fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Meaning-Centered Psychotherapy for Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Meaning-Centered Group Psychotherapy (MCP).|BEHAVIORAL: Cognitive Behavioral Psychotherapy (CBT).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK, the Measure of How the Human Body Processes a Substance) of ETX0282 When Administered Orally to Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ETX0282|DRUG: Cefpodoxime proxetil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Translational Study on Repairing Articular Cartilage Injury With Autologous Adipose Gel
Status: UNKNOWN
Conditions: Articular Cartilage Defects
Interventions: PROCEDURE: arthroscopic micro-fracture with autologous adipose gel|PROCEDURE: arthroscopic micro-fracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of 3 Doses of Paliperidone Palmitate in Treating Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Oral JYP0322 in Patients With Locally Advanced or Metastatic Cancer Targeting ROS1 Molecular Fusion.
Status: RECRUITING
Conditions: Protein Kinase Inhibitors|Other Protocol Specified Criteria|Lung Neoplasms|Brain Neoplasms
Interventions: DRUG: JYP0322
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trigeminal Nerve Cardiac Reflex During Resection of Cerebellopontine Angle Tumors and Postoperative Myocardial Injury
Status: RECRUITING
Conditions: Myocardial Injury|Trigeminal Cardiac Reflex
Interventions: OTHER: Trigeminal cardiac reflex|OTHER: Non-trigeminal cardiac reflex
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Sexual Dysfunction From Selective Serotonin Reuptake Inhibitor (SSRI) Medication: a Study Comparing Requip CR to Placebo
Status: COMPLETED
Conditions: Sexual Dysfunction
Interventions: DRUG: Ropinirole (Requip)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Statues on Endothelial Function
Status: COMPLETED
Conditions: Cardiovascular Diseases|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Functional Rehabilitation in Patients Undergoing Physiotherapy After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: THA Physiotherapy|PROCEDURE: No physiotherapy after THA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-539313|DRUG: Flurbiprofen|DRUG: Omeprazole|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of IT STX-001 in Patients With Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: STX-001|BIOLOGICAL: Keytruda®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Efficacy and Safety of DF277 Compared to Placebo in the Treatment of Otic Eczema
Status: COMPLETED
Conditions: Otic Eczema
Interventions: DRUG: DF277|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder
Status: RECRUITING
Conditions: Cardiovascular Diseases|Schizophrenia|Psychosis|Bipolar Disorder
Interventions: BEHAVIORAL: Nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Adenocarcinoma of the Gastric Cardia|Stage IIIA Esophageal Cancer|Stage IIIB Esophageal Cancer|Stage IIIC Esophageal Cancer
Interventions: DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of the Combination of Propess and AN24 Monica for Outpatient Labour Induction (PRAM)
Status: COMPLETED
Conditions: Intrapartum Fetal Monitoring|Pregnancy
Interventions: DRUG: Dinoprostone|DEVICE: Monica AN 24
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Yoga-Based Rehabilitation Program in Reducing Physical and Emotional Side Effects in Patients With Cancer
Status: COMPLETED
Conditions: Alopecia|Anxiety|Breast Carcinoma|Cognitive Side Effects of Cancer Therapy|Colorectal Carcinoma|Depression|Fatigue|Lung Carcinoma|Nausea and Vomiting|Pain|Psychological Impact of Cancer|Sleep Disorder|Weight Change
Interventions: PROCEDURE: Quality-of-Life Assessment|PROCEDURE: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-invasive Measuring of Cerebral Perfusion After Severe Brain Injury With Near-infrared-spectroscopy and ICG
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Intracerebral Hemorrhage (ICH)|Traumatic Brain Injury
Interventions: PROCEDURE: measuring cerebral perfusion by NIRS with ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Vatelizumab in Patients With Relapsing-Remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Vatelizumab|DRUG: Placebo (for Vatelizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-System Analysis of Opioid Receptor Binding
Status: RECRUITING
Conditions: Healthy|Opioid Use Disorder
Interventions: DRUG: Carfentanil, C-11|DRUG: Naloxone|DRUG: Loperamide Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration in Children With Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Muscle Weakness
Interventions: DEVICE: Whole-body vibration|OTHER: Muscle strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior CABG
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: skinoren|DRUG: differin|DRUG: skinoren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Plant Based High Protein Diet to Improve Nutritional Outcomes in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: End-Stage Renal Disease|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Plant based high protein food items
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 0,9% NaCl Effect on Kidney Function and Glycocalyx in Patients Operated on for Primary Hiparthrosis
Status: UNKNOWN
Conditions: Nephrotoxicity
Interventions: DRUG: Plasma-lyte|DRUG: 0,9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE