pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting
Status: COMPLETED
Conditions: Severe Acute Pancreatitis Patients|Duodenal Fistula|Inflammatory Intestinal Obstruction
Interventions: DIETARY_SUPPLEMENT: enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6244 With Cetuximab for Solid Tumors and Colorectal Cancer
Status: COMPLETED
Conditions: Colonic Neoplasms|Cancer of the Colon|Colon Cancer|Colon Neoplasms|Colonic Cancer
Interventions: DRUG: Cetuximab|DRUG: AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurosurgical Transitional Care Programme
Status: UNKNOWN
Conditions: Surgery|Brain Tumor|Brain Tumor, Recurrent|Brain Pathology|Spinal Diseases|Spinal Stenosis|Spinal Fusion|Trigeminal Neuralgia|Hydrocephalus|Fusion of Spine|Aneurysm|SPINAL Fracture|Chiari; Net|Skull Injuries|Brain Cancer|Brain Metastases|Brain Diseases|Brain Lesion|Brain Cyst|Spinal Curvature|Spinal Instability|Spinal Cord Neoplasms
Interventions: OTHER: Transitional Care Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Bevacizumab(BAT1706) and Comparators in Healthy Subjects
Status: COMPLETED
Conditions: NSCLC
Interventions: BIOLOGICAL: BAT1706 injection|BIOLOGICAL: EU-sourced Avastin|BIOLOGICAL: US-sourced Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
Status: RECRUITING
Conditions: Metastatic Malignant Peripheral Nerve Sheath Tumor|Neurofibromatosis Type 1|Recurrent Malignant Peripheral Nerve Sheath Tumor
Interventions: PROCEDURE: Computed Tomography|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter|OTHER: Quality-of-Life Assessment|PROCEDURE: Single Photon Emission Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Ultrasound Imaging|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Continuous Erector Spina Plane Block With Intercostal Block in Acute and Chronic Pain Control After Thoracotomy
Status: COMPLETED
Conditions: Thoracic Diseases
Interventions: PROCEDURE: intercostal block|PROCEDURE: erector spina plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer
Status: COMPLETED
Conditions: Cancer|Anxiety
Interventions: BEHAVIORAL: Coping Together Booklets and Workbook|BEHAVIORAL: Lay telephone coaching|BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nivolumab in Children and Adults With Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nasopharyngeal Cancer|Nasopharyngeal Neoplasms|Nasopharynx Cancer
Interventions: DRUG: Nivolumab|DRUG: Cisplatin|DRUG: 5-Fluorouracil|DRUG: Gemcitabine|RADIATION: Radiotherapy|DRUG: Interferon beta-1a|PROCEDURE: MRI|PROCEDURE: PET|BEHAVIORAL: Patient-Reported Outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Predicting the Integrity of Interlobar Fissures Based on Chest Image AI Technology
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Emphysema quantitative analysis software based on chest image AI technology|OTHER: artificial analysis of chest image|PROCEDURE: imported Chartis detection system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous Grafting
Status: COMPLETED
Conditions: Arteriovenous Fistula|Arteriovenous Graft|Kidney Failure, Chronic|Renal Failure, End-stage
Interventions: PROCEDURE: Supraclavicular|PROCEDURE: Pecs II block|PROCEDURE: Sham block (Grade 1)|DRUG: Ropivacaine 0.5% 20ml|DRUG: Ropivacaine 0.5% 10ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.
Status: TERMINATED
Conditions: Post Operative Analgesia
Interventions: DRUG: Paracetamol|DRUG: Nefopam|DRUG: Ketoprofen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Bio-mechanical Analysis of Adult Spinal Deformity With Sagittal Plane Misalignment
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Deformity
Interventions: OTHER: 2D versus 3D analysis of EOS stereo radiographic analysis|OTHER: Static versus dynamic analysis|OTHER: Pre- versus postoperative analysis|OTHER: Reliability of the dynamic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Liposomal Bupivacaine in Adductor Canal Blocks (ACB)
Status: WITHDRAWN
Conditions: Arthroplasty Complications|Adductor Canal Block|Peripheral Nerve Block|Opioid Use
Interventions: DRUG: Liposomal bupivacaine|PROCEDURE: Drug: SoC Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Induced Osteoporosis in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Ibandronate+alfacalcidol+calcium|DRUG: placebo ibandronate+alfacalcidol+calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Risperdal (Risperidone) for the Treatment of Behavioral Disorder Following Psychological Therapy for Challenging Behavior in Learning Disabled Children
Status: COMPLETED
Conditions: Learning Disorders|Child Behavior Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: ATO + Ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automatic Evaluation of Inflammation Activity in Ulcerative Colitis Using pCLE With Artificial Intelligence
Status: UNKNOWN
Conditions: Ulcerative Colitis|Artificial Intelligence|Confocal Laser Endomicroscopy
Interventions: DIAGNOSTIC_TEST: The diagnosis of Artificial Intelligence and endoscopist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Exendin [9-39]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MV
Status: NOT_YET_RECRUITING
Conditions: Transesophageal Echocardiography|Acute Respiratory Distress Syndrome|Right Ventricular Dysfunction
Interventions: DRUG: levosimendan|DRUG: 5% glucose injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: ERC1671|DRUG: GM-CSF|DRUG: Cyclophosphamide|DRUG: Oral Control (Sucrose pill)|DRUG: Injectable control (Sodium Chloride Injection United States Pharmacopeia (USP) (0.9%))|DRUG: Bevacizumab/Bevacizumab Biosimilar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional Awareness and Expression Therapy for People With Persistent Pain Following Orthopedic Trauma
Status: NOT_YET_RECRUITING
Conditions: Orthopaedic Trauma|Chronic Pain|Musculoskeletal Injury
Interventions: BEHAVIORAL: Emotional Awareness and Expression Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade Glioma
Status: COMPLETED
Conditions: Glioblastoma|Anaplastic Astrocytoma
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Accelerated Titration of Oxytocin for Nulliparous Patients With Labour Dystocia: ACTION Pilot Study
Status: TERMINATED
Conditions: Labour Dystocia
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal Infection
Status: COMPLETED
Conditions: Corneal Ulcers
Interventions: DRUG: Riboflavin 0.1%|OTHER: UV-X™ Illumination System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Matrix Metalloproteinase 8 Salivary Test for Diagnosis of Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Gingivitis|Infertility
Interventions: DIAGNOSTIC_TEST: salivary MMP8 test|OTHER: periodontal examination|OTHER: blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can Environmental Cleanliness be Assessed by BCA (Bicinchoninic Acid) Method
Status: COMPLETED
Conditions: Nosocomial Infection|Infection Control|Multi-antibiotic Resistance
Interventions: OTHER: BCA method for assessing environmental cleanliness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: REHABOTICS: Integrated Rehabilitation System for People With Motor Disabilities
Status: COMPLETED
Conditions: Stroke|Spasticity, Muscle|Upper Extremity Dysfunction
Interventions: DEVICE: Rehabotics Physiotherapy|OTHER: Traditional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy Vardenafil 10 mg vs Tadalafil 10 mg in in Subjects With Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Meditation, Mindfulness, and Yoga to Reduce Perceived Stress in Resident Doctors - A Randomized Controlled Trial With Crossover Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress, Job
Interventions: BEHAVIORAL: MindYou
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Robotic Arm-assisted PET/CT-guided Lung Biopsy With PET Fused CT- Fluoroscopy-guided Lung Biopsy
Status: COMPLETED
Conditions: Lung Cancer|Lung Diseases|Adenocarcinoma of Lung
Interventions: PROCEDURE: Robotic arm assisted PET/CT guided biopsy|PROCEDURE: PET fused CT-Fluoroscopy guided biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy
Status: WITHDRAWN
Conditions: Depression|Depressive Disorder|Treatment Resistant Depressive Disorder|Bipolar Disorder|Major Depressive Disorder
Interventions: DEVICE: Ultrabrief Right Unilateral|DEVICE: Brief Pulse Bitemporal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multidisciplinary Intervention in Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis; Primary|Degenerative Joint Disease of Knee
Interventions: BEHAVIORAL: Osteoarthritis education, exercise and CBT|PROCEDURE: Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Immulina on Immune Measures
Status: COMPLETED
Conditions: Effects of Immulina on Natural Killer Cells
Interventions: DIETARY_SUPPLEMENT: Immulina Dietary Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: incobotulinumtoxinA (Xeomin) (240 Units)|DRUG: incobotulinumtoxinA (Xeomin) (120 Units)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Cardiovascular Events in High Risk Orthopedic Surgical Patients
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Cerebral Vascular Disease|Peripheral Artery Disease|Renal Insufficiency|Diabetes|COPD|Hypertension|Active Smoker|Cancer|CHF|Prior DVT/PE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-Operative Thoracolumosacral Orthosis for PJK
Status: NOT_YET_RECRUITING
Conditions: Proximal Junctional Kyphosis|Adult Spinal Deformity Surgery|Thoracolumbosacral Orthosis
Interventions: DEVICE: Align PJK™ TLSO brace|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Reverse ENDocrine Resistance Trial - PD 0332991 Monotherapy vs PD 0332991 in Combination With the Endocrine Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using ICT to Deliver i-BMI to Promote Smoking Cessation Among Smokers With Chronic Diseases
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Brief Motivational Interviewing (i-BMI)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Automated Telephone Outreach With Speech Recognition to Improve Diabetes Care: A Randomized Controlled Study
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Automated Telephone Outreach with Speech Recognition|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate the Efficacy and Safety of GSK573719 Delivered Via a Novel Dry Powder Inhaler in Subjects With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719|DRUG: GSK573719|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Neoplasms|Neoplastic Cells, Circulating|Laparoscopic Surgery|Transanal Endoscopic Surgery
Interventions: PROCEDURE: Surgical approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Implementation Trial to Improve Access to Pulmonary Rehabilitation in People With COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Choice of home-based or centre-based pulmonary rehabilitation|BEHAVIORAL: Centre-based pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomegranate Juice on Memory in Older Adults
Status: COMPLETED
Conditions: Impact of Pomegranate Juice on Memory in Older Adults
Interventions: DIETARY_SUPPLEMENT: Pomegranate Juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abraxane and Lapatinib in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: lapatinib ditosylate|DRUG: paclitaxel albumin-stabilized nanoparticle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardized Educational Videos of Laparoscopic Gynecological Surgeries
Status: NOT_YET_RECRUITING
Conditions: Educational Problems|Surgery|LAP|GYN Disorders
Interventions: OTHER: Educational video tutorials
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers
Status: COMPLETED
Conditions: Cigarette Smoking-Related Carcinoma|Tobacco-Related Carcinoma
Interventions: DRUG: Broccoli Sprout/Broccoli Seed Extract Supplement|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Extension Study of Onartuzumab in Participants With Solid Tumors on Study Treatment Previously Enrolled in a Company Sponsored Study
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Onartuzumab|DRUG: Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Follicle Stimulating Hormone in Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Recurrent
Interventions: DRUG: Degarelix 120 MG [Firmagon]|DRUG: Gonal F RFF Pen 900 UNT Per 1.5 ML Pen Injector|DRUG: Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Invasives Aspergillosis in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Invasive Aspergillosis
Interventions: OTHER: Patients without antifungal prophylaxis|DRUG: Patients with antifungal prophylaxis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assess the Pharmacokinetics of Rosuvastatin and Simvastatin When Administered Alone or in Combination With Fostamatinib
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib|DRUG: Rosuvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare the Safety and Efficacy of Balloon Occluded/Plug Assisted Retrograde Transvenous Obliteration With Endoscopic Variceal Obturation for Primary Prophylaxis of Gastric Varices With Large Spontaneous Shunt
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis
Interventions: PROCEDURE: Balloon occluded/plug assisted retrograde transvenous obliteration.|PROCEDURE: Endoscopic Variceal Obturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block Versus Caudal Block for Pediatric Postoperative Analgesia
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Quadratus Lumborum Block|PROCEDURE: Caudal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Fear of Falling on Physical Performance and Quality of Life in Children With Duchenne Muscular Dystrophy
Status: UNKNOWN
Conditions: Neuromuscular Diseases|Duchenne Muscular Dystrophy|Dystrophy|Dystrophy, Muscular
Interventions: OTHER: Assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies
Status: RECRUITING
Conditions: Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)|Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)|Mantle Cell Lymphoma (MCL)|Richter's Syndrome|T-cell Lymphoma|Diffuse Large B-cell Lymphoma (DLBCL)|Marginal Zone Lymphoma|Myeloid Malignancies|Acute Myeloid Leukemia (AML)|Chronic Myelomonocytic Leukemia (CMML)|Myelodysplastic Syndrome (MDS)|MDS/Myeloproliferative Neoplasm (MPN) Overlap Syndrome
Interventions: DRUG: PRT2527|DRUG: Zanubrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of F520 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma (PTCL).
Status: UNKNOWN
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: F520
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Automated Bolus Infusion in Sciatic Nerve Catheters
Status: COMPLETED
Conditions: Hallux Valgus|Surgery
Interventions: DRUG: continuous infusion of levobupivacaine|DRUG: Intermittent bolus infusion of levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Assessment of the Precision of the Sherlock 3CG Tip Positioning System
Status: TERMINATED
Conditions: No Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC Placement
Interventions: DEVICE: Sherlock 3CG|OTHER: Blind Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Iptacopan (LNP023)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Sensory-Augmented Postural Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy
Status: RECRUITING
Conditions: Irreversible Pulpitis
Interventions: DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified DEP Regimens for the Treatment of Hemophagocytic Lymphohistiocytosis
Status: NOT_YET_RECRUITING
Conditions: Hemophagocytic Lymphohistiocytoses
Interventions: DRUG: modified-DEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: EBV specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DRUG: 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c']dipyridine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacologic Augmentation of Targeted Cognitive Training in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: AMPH|DRUG: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Speed-based and Mechanical Work Considered HIIT for Football Referees
Status: RECRUITING
Conditions: Physical Fitness
Interventions: BEHAVIORAL: Heart rate based HIIT|BEHAVIORAL: VIFT speed-based HIIT with mechanical work
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive and Cerebral Blood Flow Effects of Zanthozylum Armatum Fruit Extract in Healthy Adults Aged 30 - 55
Status: COMPLETED
Conditions: Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Zanthozylum armatum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Safety, Tolerability, and Pharmacokinetic of GMA106
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DRUG: GMA106 Injection|DRUG: GMA106 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Colonoscopy Outreach for Rural Communities Aim 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Patient Navigation|BEHAVIORAL: Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Initial Case Series With Exalt Single-Use Duodenoscope - Expanded User Experience
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: DEVICE: Exalt Model D Single-Use Duodenoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy and GM-CSF in Treating Patients With Recurrent or Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Controlled Exposure to Diesel Exhaust in Subjects With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: PROCEDURE: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intervention With n-3 Polyunsaturated Fatty Acids (PUFA)-Supplemented Products in Moderate Hypertriglyceridemic Patients
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: n-3 PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis Atopic
Interventions: DRUG: Dupilumab (SAR231893)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sonodynamic Therapy in the Treatment of Perivascular Adipose Tissue on Patients With PAD and Claudication
Status: WITHDRAWN
Conditions: Peripheral Arterial Disease
Interventions: COMBINATION_PRODUCT: Sonodynamic therapy(SDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Novel, Theory Based Physical Activity Intervention Among Adult Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivors|Exercise|Sedentary Behavior
Interventions: BEHAVIORAL: 12-Week Home Exercise Group|BEHAVIORAL: Education Comparison Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Functional Versus Non Functional Implant Loading in the Mandible
Status: COMPLETED
Conditions: Dental Implants|Edentulous Alveolar Ridge
Interventions: OTHER: immediate functional implant loading|OTHER: immediate non functional implant loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Real-world Study of Screening of Cervical Cancer Based on Photoelectric Detection
Status: NOT_YET_RECRUITING
Conditions: Uterine Cervical Cancer|High Grade Squamous Intraepithelial Lesions|Low Grade Squamous Intraepithelial Lesions
Interventions: DIAGNOSTIC_TEST: Detection of Cervical Lesions by Fluorescence Photoelectric Image
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient-specific Alloplastic Chin Implant Versus Computer Guided Genioplasty: Soft Tissue Assessment After One Year Follow up
Status: COMPLETED
Conditions: Chin Microgenia
Interventions: DEVICE: Polyetheretherketone patient specific implant|DEVICE: Computer guided advancement genioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituxan Plus FavId (Idiotype Vaccine) for Low-grade Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Id-KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Pharmacokinetics and Safety of BAT2506 Injection Versus Simponi®
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: BAT2506 injection|DRUG: Simponi® (EU commercially available product)|DRUG: Simponi® (US commercially available product)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine for Postoperative Analgesia Following Laparoscopic Bariatric Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: intrathecal morphine|DRUG: intrathecal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Imetelstat (7.5 mg/kg)|DRUG: lenalidomide standard of care|DRUG: Imetelstat (9.4 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment of Aorto-iliac Occlusions
Status: COMPLETED
Conditions: Aorto-Iliac Occlusive Disease|Iliac Artery Occlusion|Iliac Artery Disease
Interventions: DEVICE: Stenting of the Common and/or External Iliac Arteries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: pyronaridine artesunate clinical trial reference tablets|DRUG: pyronaridine artesunate to-be-marketed tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Fractional CO2 Laser on Poikiloderma of Civatte
Status: COMPLETED
Conditions: Poikiloderma of Civatte
Interventions: DEVICE: DEKA SmartXide C02 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Single-arm Pilot Study Evaluating Efficacy of Nilotinib in CML Patients With Molecular Relapse After Glivec Discontinuation Within the Context of the STIM Trials (STIM and STIM2)
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Hematological Inflammatory Indexes be Used to Differentiate Type 1 Modic Changes From Brucella Spondylodiscitis
Status: COMPLETED
Conditions: Brucella Spondylitis
Interventions: OTHER: C-Reactive Protein (CRP), Erythrocyte Sedimentation Rate (ESR), Complete Blood Count (CBC) values, and indexes derived from the CBC.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of EPA-DHA Supplement, Life Style Modification Standard Treatment on Clinical Outcome Lipid Membrane Composition in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: EPA and DHA capsules of 2 g/day|BEHAVIORAL: Stress management phone application (Eco Fusion Mentally)|BEHAVIORAL: life style program using a mobile phone (Eco Mentally and NewMe)|DEVICE: mobile phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency in 4-week Plyometric Training: Lower Limb Improvement in Sedentary Adults
Status: COMPLETED
Conditions: Plyometric Exercise|Sedentary Behavior
Interventions: OTHER: plyometric training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing Neurodevelopment in Congenital Heart Disease.
Status: UNKNOWN
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: Sonography|DEVICE: Magnetic Resonance Imaging|OTHER: Bailey Test|PROCEDURE: Surgical intervention|PROCEDURE: Brain monitoring|PROCEDURE: cord blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Influence of the Manipulation of the Sacroiliac Joint on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Sacroiliac Disorder
Interventions: OTHER: manipulation group (MG)|OTHER: electrotheraphy group (EG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD
Status: COMPLETED
Conditions: COPD Exacerbation Acute
Interventions: DRUG: Beta-Lactams|DRUG: Fluoroquinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD-tDCS for Phonological Impairment in Aphasia
Status: RECRUITING
Conditions: Aphasia|Stroke
Interventions: DEVICE: Targeted Transcranial Direct Current Stimulation|BEHAVIORAL: Speech Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Half-normal Saline in Atrial Flutter Ablation
Status: COMPLETED
Conditions: Atrial Flutter
Interventions: DRUG: Half Normal Saline 0.45% Infusion Solution Bag|DRUG: Normal Saline 0.9% Infusion Solution Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: PS-341 (VELCADE™) Versus High-Dose Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene-guided N-acetyl Cysteine for Prophylaxis of Anti-tuberculous Drug- Induced Hepatitis
Status: RECRUITING
Conditions: Tuberculosis (TB)|Isoniazid Toxicity|Rifampicin Toxicity|Pyrazinamide Adverse Reaction|Ethambutol Toxicity|NAT2 Slow Acetylator Status|NAT2 Rapid Acetylator Status|NAT2 Polymorphism|N-Acetylcysteine
Interventions: DRUG: N acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Two Doses of Intravenous NATRECOR hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
Status: COMPLETED
Conditions: Heart Failure, Congestive|Heart Decompensation
Interventions: DRUG: nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Carvedilol SR Versus Carvedilol IR in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Carvedilol SR 32mg, QD|DRUG: Carvedilol SR 64mg, QD|DRUG: Carvedilol IR 25mg, QD|DRUG: Carvedilol IR 25mg, BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Antibiotics Prophylaxis for Percutaneous Endoscopic Gastrostomy
Status: UNKNOWN
Conditions: The Patients Who Receive Percutaneous Endoscopic Gastrostomy|Peristomal Wound Infection After the Operation of PEG|Prophylactic Antibiotics Before PEG
Interventions: DRUG: cefuroxime|DRUG: Tailored antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Pharmacodynamics and Safety of LY01022 in Patients With Prostate Cancer Compared With Zoladex® 10.8mg
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Goserelin Acetate Sustained-Release Microspheres for Injection|DRUG: Zoladex 10.8 MG Drug Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on the Postoperative Experience in Children
Status: COMPLETED
Conditions: Failed Moderate Sedation During Procedure
Interventions: DRUG: dexmedetomidine|DRUG: Midazolam|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Guided Statin Therapy
Status: COMPLETED
Conditions: Hypercholesterolemia|Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction
Interventions: GENETIC: SLCO1B1*5 allele testing, results reported at randomization|GENETIC: SLCO1B1*5 allele testing, results reported at end of study|GENETIC: Genetic testing for SLCO1B1*5 allele
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mesh Versus Suture Repair for Umbilical Hernias
Status: COMPLETED
Conditions: Umbilical Hernia
Interventions: PROCEDURE: primary suture closure|DEVICE: mesh enforced closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Infusion Chemotherapy Combined With Sodium Bicarbonate for Unresectable Gastric Cancer
Status: UNKNOWN
Conditions: Successful Conversion Rate of Operation|Unresectable Gastric Cancer
Interventions: DRUG: Arterial catheter infusion chemotherapy|DRUG: Sodium Bicarbonate|DRUG: Systemic Chemotherapy|DRUG: Oral Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin (ASA) Therapy and Preeclampsia Prevention
Status: WITHDRAWN
Conditions: Preeclampsia
Interventions: DRUG: Aspirin 81 mg Enteric Coated Tab - 1 tablet|DRUG: Aspirin 81 mg Enteric Coated Tab - 2 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Evaluation of the Effect of Vitamin D Supplementation on Depressive Symptoms Among Chinese Adolescents
Status: RECRUITING
Conditions: Depressive Symptoms
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3 placebo|BEHAVIORAL: Mental health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Oesophageal Contractile Reserve in High Resolution Manometry on Post Operative Dysphagia After Anti-reflux Surgery
Status: COMPLETED
Conditions: Dysphagia
Interventions: PROCEDURE: Multiple rapid swallows test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Total Knee Arthroplasty and Augmented Reality-based Navigation System
Status: NOT_YET_RECRUITING
Conditions: Gonarthrosis
Interventions: PROCEDURE: TKR with augmented reality-based navigation system|PROCEDURE: TKR with traditional mechanically aligned technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Treatment Benefit Questionnaire in Patients With Chronic Migraine Treated With OnabotulinumtoxinA (BOTOX®)
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: BIOLOGICAL: OnabotulinumtoxinA|DRUG: Normal saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence?
Status: UNKNOWN
Conditions: IUD Insertion Complication
Interventions: DRUG: Lidocaine|DRUG: oral misoprostol|DRUG: naproxen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Education of Caregivers of Alzheimer's Patients
Status: NOT_YET_RECRUITING
Conditions: Education
Interventions: OTHER: Within the scope of the research, caregivers will be given face-to-face training in 2 sessions, 15 days apart.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bee Venom Phonophoresis on Mild to Moderate Localized Plaque Psoriasis on Knee Joint
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: COMBINATION_PRODUCT: Bee venom phonophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Language Disorders
Interventions: DRUG: Levoleucovorin Calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmote Symptom COllection to improVE postopeRative Care
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: OTHER: Voice-Assisted Remote Symptom Monitoring System (VARSMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mass Vaccine and Drug Administration, Bangladesh
Status: NOT_YET_RECRUITING
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: DHA/piperaquine and a SLD-PQ|BIOLOGICAL: Study vaccine R21/Matrix-M™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION