pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Cranial Electrotherapy Stimulation|DEVICE: Sham Cranial Electrotherapy Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-help in Adjunct to Pharmacotherapy
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: BEHAVIORAL: Self-help version of the New Forest Parenting Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation
Interventions: DRUG: Gilteritinib|DRUG: Vyxeos
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Epithelial Cancer Recurrent
Interventions: PROCEDURE: Maximal cytoreductive surgery|DRUG: HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hunova® Randomized Controlled Trial for Trunk Control Improvement in Spinal Cord Injured Patients
Status: RECRUITING
Conditions: Spinal Cord Injury
Interventions: OTHER: Standard rehabilitation|DEVICE: Hunova® rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial Evaluating the Utility of Esophageal Stitches During Laparoscopic Fundoplication
Status: COMPLETED
Conditions: Reflux
Interventions: PROCEDURE: esophageal stitches during fundoplication|PROCEDURE: no esophageal stitches placed during fundoplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Efficacy Of Tofacitinib Modified Release Tablets Compared To Tofacitinib Immediate Release Tablets In Adult Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tofacitinib|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: FTC/RPV/TAF|DRUG: FTC/RPV/TDF Placebo|DRUG: FTC/RPV/TDF|DRUG: FTC/RPV/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Formula for Children With Cow's Milk Allergy
Status: COMPLETED
Conditions: Milk Allergy
Interventions: OTHER: Experimental Extensively Hydrolyzed Formula|OTHER: Active Comparator Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oxaliplatin, Gefitinib, and Radiation Therapy in Treating Patients With Locally Advanced or Metastatic Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: gefitinib|DRUG: oxaliplatin|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: lopinavir/ritonavir|DRUG: emtricitabine|DRUG: stavudine|DRUG: tenofovir DF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Norfloxacin for Hepatopulmonary Syndrome
Status: COMPLETED
Conditions: Hepatopulmonary Syndrome
Interventions: DRUG: Norfloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Bone Metastases|Castration-Resistant Prostate Cancer
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Allergic Rhinitis
Interventions: PROCEDURE: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Somatostatin on Liver in ADPKD
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: octeotride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response or Intolerance to One Anti-Tumor Necrosis Factor (Anti-TNF) Agent
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-invasive Ways to Evaluate Lung Disease After Treatment With Xolair
Status: COMPLETED
Conditions: Lung Disease
Interventions: DRUG: Placebo|DRUG: Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RX-10045 on the Signs and Symptoms of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: RX-10045|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Translational Study of Nivolumab in Combination With Bevacizumab for Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Adult Brain Tumor
Interventions: DRUG: Nivolumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pemetrexed + Paclitaxel in Patients With Recurrent/Advanced Thyroid Cancer
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DRUG: pemetrexed + paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Ovarian Cancer: GC/FT-ICR Mass Spectrometry and Canine Olfaction
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: OTHER: Fourier transform ion cyclotron resonance mass spectrometry|OTHER: chromatography|OTHER: diagnostic laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telehealth Weight Loss Program for Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivors|Cancer of Breast|Body Weight|Overweight and Obesity
Interventions: BEHAVIORAL: Behavioral Weight-loss Program Via Telehealth|BEHAVIORAL: Behavioral Weight-Loss Program Via Telehealth - Weight Measures|BEHAVIORAL: Validated Surveys of Patient-Reported Outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocotrienol as a Nutritional Supplement in Patients With Advanced Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: Day 1: Cisplatin 75 mg/m2|DRUG: Day 1: Vinorelbine 25 mg/m2|DRUG: Day 8: Capsule vinorelbine 50 mg/m2|DRUG: Day 1: Carboplatin AUC=5|DRUG: Day 1: Vinorelbine 30 mg/m2|DRUG: Day 8: Capsule vinorelbine 60 mg/m2|DIETARY_SUPPLEMENT: Tocotrienol 300 mg x 3 daily until progression|DRUG: Placebo 1 capsule x 3 daily until progression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercising With Anxiety: Can Cognitive Behavioural Techniques Help People With Anxiety-related Disorders Exercise More?
Status: COMPLETED
Conditions: Anxiety Disorders|Posttraumatic Stress Disorder|Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Resistance training|BEHAVIORAL: Unified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Naltrexone for Post-COVID Fatigue Syndrome
Status: RECRUITING
Conditions: Post-Viral Fatigue Syndrome
Interventions: DRUG: Low-Dose Naltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LEO 43204 in Field Treatment of Actinic Keratosis on Balding Scalp Including 12-month Follow-up
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: LEO43204 gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aceis on Peritoneal Protein Loss and Solute Transport in pd Patients
Status: COMPLETED
Conditions: Disorders Associated With Peritoneal Dialysis
Interventions: OTHER: Group using angiotensin converting enzyme inhibitor|OTHER: Group not using angiotensin converting enzyme inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of IBI302 in Patients With nAMD
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: Low dose IBI302|BIOLOGICAL: High dose IBI302|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Self-administered Acupressure to Improve Cancer-related Fatigue Among Cancer Patients Undergoing Chemotherapy
Status: RECRUITING
Conditions: Cancer, Breast|Fatigue|Acupressure|Exercise
Interventions: BEHAVIORAL: Self-administered acupressure|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Radial Extracorporeal Shockwave Therapy Applied to the Achilles Tendon Influence Ankle Functionality?
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Radial Extracorporeal Shockwave Therapy|DEVICE: Sham Extracorporeal Shockwave Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing of Different Methods for Determining Whether Breast Cancer Has Spread to the Lymph Nodes
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Fine needle aspiration biopsy (FNAB)|PROCEDURE: Sentinel Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Functional Confections in Promoting Oral Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Health|Oral Cancer|Gum Disease
Interventions: OTHER: Strawberry gummy|OTHER: Placebo control gummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Novel Immunotherapy PD-1 Antiboty to Suppress Recurrence of HCC Combined With PVTT After Hepatic Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: PD-1 antibody|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of Efficacy and Safety of Glofitamab in Combination With Salvage Therapy in a Real-world Setting in Chinese Adult Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma.
Status: RECRUITING
Conditions: B-cell Non-Hodgkin Lymphoma
Interventions: DRUG: Glofitamab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells for Gastric/Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Claudin18.2-Targeted Chimeric Antigen Receptor T Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006)
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: Samatasvir|DRUG: Omeprazole|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Efficacy Study of DermaPure™ to Treat Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: OTHER: DermaPure™|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Grape Seed Extract on Circulatory Measures in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Circulatory; Change
Interventions: DRUG: Grape Seed Extract|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of COVID-19 on Family Dynamics on Bandebereho Study Participants
Status: COMPLETED
Conditions: Gender Relations|Partner Communication|Division of Carework|Couple Conflict|Stress
Interventions: BEHAVIORAL: MenCare+/Bandebereho fathers'/couples' group education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Purpose of This Research Study is to Compare the Efficacy and Safety of SCT630 and Adalimumab (HUMIRA®) in Adults With Plaque Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: BIOLOGICAL: SCT630|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DYNAMIC Study (DoxycYcliNe AMbulatoIre COVID-19)
Status: WITHDRAWN
Conditions: COVID19
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Colorectal Cancer|Rectal Cancer Stage II|Rectal Cancer Stage III
Interventions: BEHAVIORAL: Prehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electroconvulsive Therapy for Traumatic Memories
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Traumatic memory reactivation|BEHAVIORAL: Neutral memory reactivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Haemodynamic Effects of Mechanical Standard and Active Chest Compression-decompression During Out-of-hospital CPR
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: LUCAS2 AD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of CV Risk Prediction Tools Based on AI and Fundus Imaging Technology Study (PERFECT)
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: fundus photograpgy|DIAGNOSTIC_TEST: optical coherence tomography|DIAGNOSTIC_TEST: optical coherence tomography angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robotic Assisted vs Custom Made Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Custom made Total Knee Arthroplasty|DEVICE: Functionally aligned robotically assisted total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges
Status: COMPLETED
Conditions: Postoperative Cardiac Complication|Heart Failure|Left Ventricular Cardiac Dysfunction|Inappropriate Phrenic Nerve Stimulation|Perioperative/Postoperative Complications
Interventions: PROCEDURE: BiP Group|DEVICE: Quad Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Trans-Arterial Chemo-Embolization (TACE) Adjuvant HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Brivanib|OTHER: Brivanib Placebo|PROCEDURE: TACE Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Treatment in Immune Thrombocytopenic Purpura (ITP) Patients
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura|Helicobacter Pylori Infection
Interventions: DRUG: H. pylori triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin-based and Carboplatin-based Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Cisplatin|Carboplatin|NPC
Interventions: DRUG: Docetaxel,Carboplatin|DRUG: Docetaxel,Cisplatin|RADIATION: Carboplatin-based concurrent chemoradiotherapy|RADIATION: Cisplatin-based concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Spondylolysisin Pediatric Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain|Stress Fracture
Interventions: OTHER: Soft spinal brace|OTHER: thoracolumbar orthosis|OTHER: Excersice restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Corneal Residence Time of Chitosan-N-acetylcysteine Eye Drops in Patients With Dry Eye Syndrome After Single and Multiple Instillation
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Chitosan- N- Acetylcysteine eye drops|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dry Needling With a Standard Exercise Programme on Pain and Quality of Life in Patients With Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: COMBINATION_PRODUCT: Dry needling with exercise|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women
Status: WITHDRAWN
Conditions: Contraceptive Devices|Long-Acting Reversible Contraception|Analgesia|Adolescent Health|Gynecology
Interventions: DRUG: Nitrous oxide gas for inhalation|DRUG: Oxygen Gas for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Mazira Project: An Evaluation of Eggs During Complementary Feeding in Rural Malawi
Status: COMPLETED
Conditions: Infant Malnutrition
Interventions: OTHER: Eggs|BEHAVIORAL: Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ischemic Preconditioning on Conditioned Pain Modulation and Heart Rate Variability in Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Preconditioning
Interventions: DEVICE: Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Activated Recombinant Human Factor VII in Refractory Haemorrhagic Cystitis
Status: COMPLETED
Conditions: Other Haemostasis Disorder|Haemorrhagic Cystitis
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Iloprost and Eptifibatide in Septic Shock Patients
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Iloprost+eptifibatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Prospective Trial of mXELOXIRI Reintroduction for mCRC
Status: UNKNOWN
Conditions: Unresectable Metastatic Colorectal Carcinoma
Interventions: DRUG: Capecitabine-Oxaliplatin-Irinotecan-Bevacizumab Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 24-week Computerized Cognitive Training in Patients With MCI and AD
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: OTHER: Computerized Cognitive Training|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAPA-Keloid Study of Keloid Regression
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: Rapamycin 8% Ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Bispectral Index (BIS) for Monitoring of Total Intravenous Anaesthesia in Pediatric Patients
Status: TERMINATED
Conditions: Anesthesia, General
Interventions: DRUG: Propofol|DRUG: Remifentanil|DEVICE: Bispectral Index Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Malignant Sinonasal Tumours With Intensity-modulated Radiotherapy (IMRT) and Carbon Ion Boost (C12)
Status: COMPLETED
Conditions: Sinonasal Malignancies|Adenocarcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses
Interventions: RADIATION: carbon ion boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia, Refractory
Interventions: DRUG: Ceramide NanoLiposome (Ceraxa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Training Provided According to the Health Promotion Model on Healthy Lifestyles and Self-efficacy in Adolescents
Status: COMPLETED
Conditions: Adolescent Health
Interventions: BEHAVIORAL: healthy lifestyle education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Granulocyte-macrophage Colony-stimulating Factor, Interferon and Interleukin-2 as Adjuvant Treatment for Renal Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: GM-CSF, IFN alpha and IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Esophageal Cancer|Hepatocellular Carcinoma|Non-small Cell Lung Cancer|Small Cell Lung Cancer|Ovarian Epithelial Cancer|Carcinoma Breast Stage IV|Hormone-refractory Prostate Cancer|Head and Neck Cancers- Squamous Cell|Renal Cell Cancer|Urinary Bladder Neoplasms|Cervical Cancer|Endometrial Cancer|Glioblastoma Multiforme|Triple Negative Breast Cancer|Pancreatic Cancer
Interventions: DRUG: Sacituzumab Govitecan-hziy (SG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Tiotropium low dose mcg|DRUG: Tiotropium high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Whole Genome Trio Sequencing as a Standard Routine Test in Patients With Rare Diseases - "GENOME FIRST APPROACH"
Status: COMPLETED
Conditions: Rare Diseases|Genetic Predisposition
Interventions: GENETIC: WGS-Diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measurement of Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Pentoxifylline and Vitamin E in the Treatment of Late Radiation Related Injuries
Status: TERMINATED
Conditions: Wounds and Injuries
Interventions: DRUG: pentoxifylline|DRUG: α-Tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RNA Sequencing Analysis in Large Vessel Occlusion Stroke DATA Bank
Status: UNKNOWN
Conditions: Stroke, Acute|Thrombosis
Interventions: PROCEDURE: mechanical thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety of Tetraxim Versus Local DTP + IPV
Status: COMPLETED
Conditions: Pertussis|Diphtheria|Poliomyelitis|Tetanus
Interventions: BIOLOGICAL: DTaP-IPV combined vaccine|BIOLOGICAL: DTaP vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?
Status: COMPLETED
Conditions: Vitamin D Deficiency|Cardiomyopathies|Apoptosis|Inflammation
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Crohn's Disease|Gastrointestinal Diseases|Digestive System Diseases|Intestinal Diseases
Interventions: DRUG: Mesalazine, Tripterygium glycosides
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Use of Probiotic S. Boulardii on Acute Viral Inflammatory Diarrhea Diagnosed With Multiplex PCR.
Status: COMPLETED
Conditions: Viral Diarrhea
Interventions: DIETARY_SUPPLEMENT: Saccharomyces boulardii (Floratil 600mg)|DIETARY_SUPPLEMENT: 3 capsules of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Shockwave Therapy for Erectile Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Erectile Dysfunction|Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction Following Radiation Therapy|Erectile Dysfunction Due to General Medical Condition|Erectile Dysfunction Due to Arterial Insufficiency
Interventions: DEVICE: Storz Duolith Low-Intensity Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: ALG-097558|DRUG: Placebo|DRUG: Midazolam|DRUG: Itraconazole|DRUG: Carbamazepine|DRUG: ALG-097558 in solution formulation|DRUG: ALG-097558 in tablet formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating and Predicting Response to a Single Session Intervention for Self-Dislike
Status: UNKNOWN
Conditions: Depressive Symptoms|Self-Appraisal
Interventions: BEHAVIORAL: Single Session Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celiac Disease School for Women Living on a Gluten-free Diet
Status: UNKNOWN
Conditions: Education of Patients|Counseling|Problem-Based Learning
Interventions: BEHAVIORAL: Celiac school|BEHAVIORAL: Usual care of celiac disease women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed Glioblastoma
Status: UNKNOWN
Conditions: Glioblastomas|Gliosarcoma
Interventions: OTHER: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of Mastiha Oil in Adults With Hypertriglyceridemia
Status: NOT_YET_RECRUITING
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: MastihaOil|BEHAVIORAL: nutritional counsel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Keratized Mucosa in CG Implant Placement: CTG vs Flapless
Status: RECRUITING
Conditions: Variation of Keratinized Mucosa After Implant Surgery
Interventions: PROCEDURE: Connective tissue graft|PROCEDURE: Flapless
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Four Doses of Glycopyrronium Bromide (NVA237) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), in Comparison to an Active Comparator Tiotropium
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Placebo|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PBF-677 in Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: PBF-677|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics
Status: UNKNOWN
Conditions: Diabetes Mellitus|Chronic Periodontitis
Interventions: DRUG: Placebo|DRUG: 3g omega-3 plus 100mg aspirin daily for 60 days|DRUG: omega-3 plus aspirin before periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Concomitant Intensity-modulated Radiotherapy Combined to Capecitabine, Mitomycin and Panitumumab in Patients With Stage II-IIIB Squamous-cell Carcinoma of the Anal Canal
Status: TERMINATED
Conditions: Carcinoma of Anal Canal
Interventions: RADIATION: RADIOTHERAPY|BIOLOGICAL: PANITUMUMAB|DRUG: MITOMYCIN|DRUG: CAPECITABINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Japanese Patients With Neovascular AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Abicipar pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belimumab Phase I Study in Chinese Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EZIO Compared to Central Venous Lines for Emergency Vascular Access
Status: WITHDRAWN
Conditions: Catheters, Indwelling|Central Venous Line|Intraosseous Needle
Interventions: DEVICE: Powered Intraosseous device (EZIO)|DEVICE: standard central line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate a Pharmacokinetic Characteristics and the Safety of AG1502 in Healthy Male Subjects
Status: UNKNOWN
Conditions: Healthy Male Subjects
Interventions: DRUG: Atorvastatin + Candesartan|DRUG: AG1502
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Reliability and Validity of Strength Measurements of the Lower Limbs in Children With Bilateral Spastic Cerebral Palsy.
Status: COMPLETED
Conditions: Children|Cerebral Palsy|Muscle Weakness
Interventions: OTHER: Functional strength assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food and Alcohol Behavior Study: Meaningful Enhancement
Status: ACTIVE_NOT_RECRUITING
Conditions: Folate Deficiency
Interventions: DIETARY_SUPPLEMENT: Methyl Folate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Stress Response and Anxiety Score in Paediatric Patients
Status: COMPLETED
Conditions: Anxiety and Fear|Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Care After Pregnancy Study (CAPS): Engaging Women in Postpartum Care
Status: COMPLETED
Conditions: Postpartum Care
Interventions: BEHAVIORAL: Healthy Beyond Pregnancy|BEHAVIORAL: Pre-Scheduled Postpartum Visit|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of Conversational AI Service (Chatbot) Utilization on Vaccine Confidence
Status: UNKNOWN
Conditions: Vaccination Hesitancy
Interventions: OTHER: Conversational AI Service (Chatbot)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sedentary Behavior Interrupted: A Trial of Acute Effects on Biomarkers of Healthy Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Frequent sit-to-stands|BEHAVIORAL: Stand More
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sequence of Vessel Interruption and Circulating Tumor Cells in Surgical Lung Cancer
Status: UNKNOWN
Conditions: Circulating Tumor Cell|Lung Cancer|Surgery
Interventions: PROCEDURE: Vein interruption before any other surgical manipulation|PROCEDURE: Arteries interruption before vein interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
Status: COMPLETED
Conditions: Necrotizing Soft Tissue Infection|Necrotizing Fascitis|Gas Gangrene|Fournier Gangrene
Interventions: DEVICE: Hyperbaric oxygen therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Association Between Functional Changes in the Brain and the Perception of Pain in Patients With Inflammatory Bowel Diseases (IBD) - Measured With Functional Magnetic Resonance Imaging.
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Unresectable Pancreatic Adenocarcinoma
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Microbiome Modulation With Prebiotics in PTSD and Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis|PTSD
Interventions: DIETARY_SUPPLEMENT: Resistant potato starch|DIETARY_SUPPLEMENT: Powdered cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Concurrent Chemoradiation Versus Wide Pelvic Lymphadenectomy for Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: PROCEDURE: CCRT, Pelvic lymphadenoectomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-Establishing Flow Via Drug Coated Balloon for the Treatment of Urethral Stricture Disease - Registry Study
Status: WITHDRAWN
Conditions: Urethral Stricture|Urethral Stricture, Anterior|Lower Urinary Tract Symptoms|Anterior Urethral Stricture
Interventions: DEVICE: Optilume Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Polyphenol-rich Dark Chocolate on Body Weight in Overweight and Obese Adults
Status: COMPLETED
Conditions: Body Weight
Interventions: OTHER: Polyphenol-rich Dark chocolate|OTHER: Placebo Dark chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient-specific Positioning Guides (PSPG) Technique Versus Conventional Technique in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Gonarthritis
Interventions: PROCEDURE: TKR with Positioning Guides (PSPG)|PROCEDURE: TKR with Conventional Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)
Status: TERMINATED
Conditions: Diabetic Macular Edema
Interventions: DRUG: KSI-301|DRUG: Aflibercept|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer
Status: TERMINATED
Conditions: Estrogen Receptor-positive Breast Cancer|Gastrinoma|Glucagonoma|HER2-negative Breast Cancer|Insulinoma|Mucositis|Oral Complications|Pancreatic Polypeptide Tumor|Progesterone Receptor-positive Breast Cancer|Recurrent Breast Cancer|Recurrent Islet Cell Carcinoma|Recurrent Renal Cell Cancer|Somatostatinoma|Stage III Renal Cell Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doravirine Concentrations and Antiviral Activity in Cerebrospinal Fluid in HIV-1 Infected Individuals
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Doravirine|DRUG: Descovy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 89Zr-Oxine-RY_SW01 Cell Injection for the Treatment of Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: 89Zr-Oxine-RY_SW01 Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mouth Rinses in Type 1 and Type 2 Diabetic Participants
Status: COMPLETED
Conditions: Gingivits in Diabetics
Interventions: OTHER: Listerine Cool Mint|OTHER: 5% Hydroalcohol Mouth Rinse|OTHER: Colgate Cavity Protection Toothpaste|OTHER: Alcohol-Free Essential Oil Containing (AFEO) Mouth Rinse Lead Formula|DEVICE: Concept Curve Winter Series Toothbrush|DEVICE: Listerine Cool Mint Floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery
Status: WITHDRAWN
Conditions: Corneal Ectasia
Interventions: DRUG: riboflavin: 0.12% riboflavin ophthalmic solution with the KXL system|DRUG: placebo: 0.0% riboflavin ophthalmic solution with the KXL system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Placebo Controlled Trial Evaluating Rasagiline Effects on Cognition in Parkinson's Disease Patients With Mild Cognitive Impairment Receiving Dopaminergic Therapy
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline/Placebo|DRUG: Rasagiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Resveratrol (1000mg twice a day), Myoinositol 1000mg (Twice a day)|DRUG: Metformin (500 mg Twice a day), Pioglitazone (15 mg Twice a day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Ankaferd Blood Stopper in the Management of Traumatic Bleeding
Status: COMPLETED
Conditions: Bleeding Disorder
Interventions: PROCEDURE: Ankaferd Blood Stopper in theTraumatic Bleeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cost/Effectiveness Analysis of the Respiratory Poligraphy at Home
Status: COMPLETED
Conditions: Suspected Sleep Apnea|Daytime Sleepiness
Interventions: DEVICE: PSG (polysomnography)|OTHER: PR (respiratory polygraphy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC