pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tolerance of the vNOTES Surgical Technique in Total Hysterectomy for Benign Lesion. Clinical Trial of Non-inferiority Compared to the Laparoscopic Technique.
Status: RECRUITING
Conditions: Hysterectomy|Laparoscopy|vNOTES
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: vNOTES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bimatoprost Ophthalmic Solution in Increasing Eyelash Prominence
Status: COMPLETED
Conditions: Eyelash Hypotrichosis
Interventions: DRUG: bimatoprost ophthalmic solution 0.005%|DRUG: bimatoprost ophthalmic solution 0.015%|DRUG: bimatoprost ophthalmic solution 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study of GNC-038 Injection in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Non-hodgkin's Lymphoma
Interventions: DRUG: GNC-038
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Face Perception vs. Memory Training to Improve Face Recognition in Developmental Prosopagnosia
Status: RECRUITING
Conditions: Developmental Prosopagnosia
Interventions: BEHAVIORAL: Face Memory Training|BEHAVIORAL: Face Perception Training|BEHAVIORAL: Placebo control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Apolipoprotein (APO)E Genotype, Meal Fatty Acids, Postprandial Lipaemia
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: High saturated fat meal|DIETARY_SUPPLEMENT: Saturated fatty acids and fish oil meal|DIETARY_SUPPLEMENT: High unsaturated fat meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab in Combination With Vinorelbine and Trastuzumab for HER2-Positive, Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab|DRUG: vinorelbine|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transversalis Fascia Plane Block Versus Wound Infiltration in Varicoselectomy Surgery
Status: COMPLETED
Conditions: Analgesia|Transversalis Fascia Plane Block|Wound Infiltration|Varicoselectomy
Interventions: PROCEDURE: Wound site infiltration|PROCEDURE: Transversalis fascia plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Mitral Valve Insufficiency|Aortic Valve Stenosis|Aortic Valve Regurgitation|Mitral Valve Stenosis|Coronary Artery Bypass Graft Triple Vessel
Interventions: PROCEDURE: Ambulation orderly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MSC and HSC Coinfusion in Mismatched Minitransplants
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute|Leukemia, Lymphoblastic, Acute|Leukemia, Myelocytic, Chronic|Myeloproliferative Disorders|Myelodysplastic Syndromes|Multiple Myeloma|Leukemia, Lymphocytic, Chronic|Hodgkin's Disease|Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Mesenchymal stem cells|OTHER: Isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Topic Cervical Anesthesia for Pain Control During Endouterine Manual Aspiration
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Αn Information System for Symptom Diagnosis and Improvement of Attention Deficit Hyperactivity Disorder (ADHD360)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: ADHD360 platform: An intervention intergrating a serious game along with a mobile application for daily behavioral monitoring.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Theory-based Digital Intervention to Promote Weight Loss and Weight Loss Maintenance
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Choosing Health Intervention|BEHAVIORAL: Choosing Health Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety and Immunogenicity of Different Formulations of GSK Biologicals' Meningococcal ACWY Conjugate Vaccine (GSK3536820A and Menveo) Administered to Healthy Adolescents and Young Adults 10 to 40 Years of Age
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: MenACWY liquid|BIOLOGICAL: MenACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Unilateral Lumbar Mobilisations on Hamstring Strength and Failure Point of the Hamstring Nordic Exercise
Status: COMPLETED
Conditions: Hamstring Injury
Interventions: OTHER: Lumbar Mobilisations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Chorionic Gonadotropin Versus Granulocyte Colony Stimulating Factor in Increasing Pregnancy Rate in ICSI
Status: UNKNOWN
Conditions: Fertility Disorders
Interventions: DRUG: Granulocyte Colony Stimulated Factor|DRUG: Human Chorionic Gonadotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 'Medical Nutrition Therapy' on Post-bariatric Hypoglycemia 2-4 Years After Gastric Bypass Surgery
Status: COMPLETED
Conditions: Hypoglycemia|Obesity, Morbid
Interventions: BEHAVIORAL: Regular diet|BEHAVIORAL: 10-point nutrition plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol (CBD) for the Treatment of Alcohol Withdrawal
Status: UNKNOWN
Conditions: Alcohol Withdrawal|Alcohol Dependence
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study on a New Oral Pentamidine Formulation in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Oral Pentamidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Neurovascular Adaptations in Aging Women
Status: NOT_YET_RECRUITING
Conditions: Women|Sympathetic Nervous System|Aging|Blood Flow
Interventions: DRUG: Norepinephrine|DRUG: Isoproterenol|DRUG: Acetylcholine|DRUG: Nitroprusside|DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Treatment of Gingival Recessions
Status: COMPLETED
Conditions: Clinical Trial|Connective Tissue|Gingival Recession|Microsurgery
Interventions: PROCEDURE: surgical techniques in the treatment of localized gingival recession defects.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vaginal Mesh for Anterior Prolapse
Status: COMPLETED
Conditions: Vaginal Prolapse|Uterine Prolapse|Cystocele|Pelvic Organ Prolapse
Interventions: DEVICE: synthetic polypropylene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREMIER: PREvention of Metabolic Illness Through prEcision nutRition
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Type 2 Diabetes|Metabolic Syndrome|Diet Habit|Nutritional and Metabolic Disease|Food Preferences
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Denosumab and Teriparatide Study (DATA-HD and DATA-EX)
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: denosumab|DRUG: teriparatide|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-production and Feasibility RCT of Intervention to Improve the Mental Health of Children With a Social Worker
Status: RECRUITING
Conditions: Parent-Child Relations|Child Mental Disorder|Child Maltreatment
Interventions: OTHER: Infant Parent Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD4573 as Monotherapy or in Combinations With Anti-cancer Agents in Patients With r/r PTCL or r/r cHL
Status: COMPLETED
Conditions: Relapsed/Refractory Peripheral T-cell Lymphoma|Relapsed/Refractory Classical Hodgkins Lymphoma
Interventions: DRUG: AZD4573
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-crystal E-58425 vs Tramadol and Celecoxib for Moderate to Severe Acute Pain After Bunionectomy. Phase III Clinical Trial.
Status: COMPLETED
Conditions: Acute Post-surgical Pain
Interventions: DRUG: Co-crystal E-58425 (Tramadol/Celecoxib)|DRUG: Tramadol (Ultram®)|DRUG: Celecoxib (Celebrex®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of VS 105
Status: COMPLETED
Conditions: Chronic-kidney Disease Stage 5D on Stable Hemodialysis
Interventions: DRUG: Single VS-105/placebo to healthy|DRUG: Multiple VS-105/placebo to healthy|DRUG: Multiple VS-105/placebo to HD subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Preventing Human Papillomavirus Infection in Younger Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Prevention of Human Papillomavirus Infection
Interventions: BIOLOGICAL: quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine or nonavalent human papillomavirus vaccine (HPV 6, 11, 16, 18, 31, 33, 45, 52, 58)|OTHER: laboratory biomarker analysis|OTHER: survey administration|OTHER: medical chart review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Effects of BMS-986036 on the Body in Healthy Japanese and Non-Japanese Subjects
Status: COMPLETED
Conditions: Metabolics
Interventions: DRUG: Placebo|DRUG: BMS-986036
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Postoperative Analgesia in Bunionectomy
Status: COMPLETED
Conditions: Bunion|Hallux Valgus
Interventions: DRUG: SKY0402|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABI-007 In Combination With Bevacizumab in Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: ABI-007|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Osteo Arthritis Shoulders|Synovitis of Knee|Synovitis/Tenosynovitis - Hip|Synovitis|Pain, Chronic
Interventions: DEVICE: Shoulder/Hip/Knee Embolization with Embozene Microspheres
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Electroacupuncture on Refractory Pain in Juvenile Rheumatoid Arthritis: Randomized Controlled Trial
Status: UNKNOWN
Conditions: Juvenile Rheumatoid Arthritis
Interventions: DEVICE: naproxen phonophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Roentgen Stereophotogrammetric Analysis (RSA) and Dual Energy X-ray Absorptiometry (DEXA) to Evaluate Fixation of Periapatite Coated Triathlon Total Knee Arthroplasty (TKA) Components
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Triathlon Periapatite (PA)-coated Tibial Component
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticipatory Counseling on LNG-IUS Continuation, Utilization and Satisfaction
Status: UNKNOWN
Conditions: Vaginal Bleeding|Uterine Cramping
Interventions: OTHER: Anticipatory Counseling|OTHER: Cancer Screening Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of ABR-215050 to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ABR-215050, tasquinimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients With Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Arthralgia|Breast Neoplasms
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Ateronon in Patients With Coronary Disease to Evaluate Its Effectiveness in Assessing the Risk Factors of Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Ateronon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Scaling Up Early Childhood Development in Zambia
Status: COMPLETED
Conditions: Early Childhood Development
Interventions: OTHER: SMAGs trained on ECD curriculum|OTHER: Head women trained on ECD curriculum|BEHAVIORAL: Head women led parent groups|OTHER: Usual care of children 0-5 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COVID-19 Bivalent Booster Megastudy
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: COVID Booster text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of a Novel Immune Modulating Dietary Supplement on House Dust Mite Induced Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Dust Mite Allergy|Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: holo-BLG (beta-lactoglobulin) - a major component of the protein fraction of raw milk, is loaded with ligands such as retinoic acid, zinc and polyphenol-iron complexes.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity and Safety of DTP-HB-Hib Using New Hepatitis B Bulk (Bio Farma)
Status: NOT_YET_RECRUITING
Conditions: Diphtheria Vaccine Adverse Reaction|Tetanus Vaccine Adverse Reaction|Pertussis Vaccine Adverse Reaction|Haemophilus Influenzae Type B Vaccine Adverse Reaction|Hepatitis B Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Recombinant Hepatitis B new Bulk vaccine|BIOLOGICAL: DTP-HB-Hib with Recombinant Hepatitis B new Bulk vaccine|BIOLOGICAL: Recombinant Hepatitis B vaccine (Registered BioFarma)|BIOLOGICAL: Pentabio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution
Status: COMPLETED
Conditions: Keratoconus|Pellucid Marginal Corneal Degeneration|Corneal Degeneration|Corneal Ectasia
Interventions: COMBINATION_PRODUCT: PXL-330 Platinum device for crosslinking with Peschke riboflavin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LVRS Versus BLVR in Patients With Homogenous Emphysema, CLUB-HE Trial
Status: RECRUITING
Conditions: Emphysema or COPD
Interventions: PROCEDURE: Lung volume reduction surgery|PROCEDURE: Bronchoscopic lung volume reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: Edasalonexent|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Status: COMPLETED
Conditions: Infertility|Ovulation Induction
Interventions: DRUG: Gonalef® (Follitropin alfa)|DRUG: Purified pituitary gonadotropin (Fertinorm-P®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Virtual Reality as an Adjunct in Procedural Preparation for Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Virtual Reality|Paediatrics|Radiology
Interventions: BEHAVIORAL: Virtual Reality|BEHAVIORAL: Simulator Preparation|BEHAVIORAL: Preparation Booklet for Non-Sedated MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: OTHER: Nasal CPAP|OTHER: Humidified High Flow Nasal Cannula (HHFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Recovery in Patients After Acute Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: OTHER: Robot-assisted treadmill gait training (RTGT)|OTHER: Therapist-assisted treadmill gait training (TTGT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Energy Availability on Menstrual Cycle Function
Status: NOT_YET_RECRUITING
Conditions: Menstrual Irregularity
Interventions: DIETARY_SUPPLEMENT: Artificially Sweetened Carbohydrate Beverage|DIETARY_SUPPLEMENT: Artificially Sweetened Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-world, 52-week Prospective Study to Capture the Reasons for Switch to Triple Combination Therapy, Assess the Clinical and Patient Reported Outcomes in Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Trixeo Aerosphere™ in Routine Care Settings in Greece
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive (COPD)
Interventions: COMBINATION_PRODUCT: Budesonide Glycopyrronium bromide Formoterol fumarate pressurized Metered Dose Inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Critical Illness Recovery Navigator for Alcohol
Status: TERMINATED
Conditions: Alcohol Use Disorder (AUD)
Interventions: BEHAVIORAL: Recovery Navigator on an as needed basis up to 6 months|BEHAVIORAL: Recovery Navigator prior to hospital discharge|OTHER: No interaction with Recovery Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Added Value of Cone Beam CT Guidance to Electromagnetic Navigation Bronchoscopy for the Diagnosis of Pulmonary Nodule.
Status: COMPLETED
Conditions: Lung Cancer|Pulmonary Disease
Interventions: PROCEDURE: ENB followed by trans-bronchial biopsy and trans-bronchial cryobiopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Kinesiotape on Quadriceps and Gluteus in Counter Movement Jump and Sprint in Soccer Players
Status: COMPLETED
Conditions: Sports Physical Therapy|Athletics|Performance
Interventions: OTHER: Kinesiotape of the physical performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Constraint Induced Movement Therapy in Preschool Cerebral Palsy After Botulism Toxin Injection
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic|Rehabilitation
Interventions: PROCEDURE: 40-hour constraint-induced movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Alzheimer's Disease Feasibility (TADF)
Status: UNKNOWN
Conditions: Alzheimer Disease|Healthy Aging
Interventions: DEVICE: BrightGo cognitive training|DRUG: Standard of Care medication for early Alzheimer's Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Dense Chemotherapy and Rituximab for Young High Risk Diffuse Large B-Cell Lymphoma Patients (CRY-04)
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: R-CHOEP14x6+HD-AraC+HD-Mtx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effect of Food on the Blood Levels of AST2818 Following Single Oral Doses in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: AST2818 Tablets|DRUG: AST2818 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Mild Cognitive Impairment|Huntington Disease
Interventions: DEVICE: MHSL- SleepBand|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Glucose Intolerance|Insulin Resistance
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% Sodium-chloride|DRUG: Fentanyl|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Sentinel Navigation Surgery in Early Gastric Cancer Using Fluorescence (SENORITA4)
Status: NOT_YET_RECRUITING
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: Laparoscopic sentinel navigation surgery using fluorescence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visualisation of a Digital Care Pathway.
Status: UNKNOWN
Conditions: Type 2 Diabetes|Multidisciplinary Communication|Empowerment|Patient Empowerment|Patient Acceptance of Health Care
Interventions: OTHER: visualisation of a digital care path
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of Intra-aortic Balloon Pump Before Surgery for Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Coronary Artery Disease|Coronary Bypass Graft Stenosis of Autologous Vessel|Troponin|IABP - Disorder of Intra-Aortic Balloon Pump
Interventions: OTHER: Intra-aortic Balloon Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orthodontic Retention on the Maxillary Stability After SARME Using Laser Scanner
Status: COMPLETED
Conditions: Maxillary Hypoplasia
Interventions: PROCEDURE: Surgically Assisted Rapid Maxillary Expansion (SARME)|OTHER: Laser Scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CCRT for Esophageal Cancer.
Status: COMPLETED
Conditions: Esophageal Cancer|Concurrent Chemoradiotherapy|Oxaliplatin|Paclitaxel
Interventions: DRUG: Paclitaxel|DRUG: Oxaliplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of PLX-200 in Patients With CLN3
Status: NOT_YET_RECRUITING
Conditions: Juvenile Neuronal Ceroid Lipofuscinosis
Interventions: DRUG: PLX-200|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-blind, Placebo-controlled Study
Status: UNKNOWN
Conditions: Upper Respiratory Tract Infection
Interventions: DRUG: Muntelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Standing Cognition and Co-morbidities of POTS Evaluation
Status: COMPLETED
Conditions: Postural Tachycardia Syndrome|Ehlers-Danlos Syndrome
Interventions: BEHAVIORAL: Standing|BEHAVIORAL: Supine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Review of Efficacy of Used ultraSonic Energy Device
Status: COMPLETED
Conditions: Appendicitis Acute|Safety Issues|Complication of Surgical Procedure|Device Induced Injury
Interventions: DEVICE: New Device|DEVICE: Used Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cooperative Lifestyle Programs (CLIP-II)
Status: COMPLETED
Conditions: Cardiovascular Disease|Obesity|Physical Disability
Interventions: BEHAVIORAL: Caloric restriction|BEHAVIORAL: Aerobic Training|BEHAVIORAL: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Ttransendoscopic Enteral Tubing in Mid-gut
Status: UNKNOWN
Conditions: Transendoscopic Enteral Tubing
Interventions: PROCEDURE: transendoscopic enteral tubing in mid-gut
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The AIPLAQUE Study: An Artificial Intelligence-based Prospective Study to Analyze PLAQUE Using CCTA
Status: RECRUITING
Conditions: Coronary Artery Disease Acute Coronary Syndrome Myocardial Ischemia Plaque Characterization
Interventions: DEVICE: CCTA CT-FR CAG OCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Decompensated Hepatitis B Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Decompensated Liver Cirrhosis
Interventions: BIOLOGICAL: Human Umbilical Cord Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia
Status: COMPLETED
Conditions: Pain Measurement|Visual Analog Pain Scale
Interventions: DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Repeat Resection in Recurrent Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma|Glioblastoma - Category
Interventions: PROCEDURE: Repeat Surgical Management of Recurrent GBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
Status: UNKNOWN
Conditions: Hoarseness|Dysphonia|Aphonia|Vocal Fold; Scar
Interventions: BIOLOGICAL: MSC-KI-PL-204
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiome in Fecal Samples From Patients With Metastatic Cancer Undergoing Chemotherapy or Immunotherapy
Status: TERMINATED
Conditions: Metastatic Carcinoma|Stage IV Colorectal Cancer|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ST36 Acupoint Injection With Anisodamine for Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: PROCEDURE: ST36 acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development, Implementation and Evaluation of a Clinical Practice Guideline for Care of Preterm Infants Receiving Non-invasive Ventilation (NIV)
Status: UNKNOWN
Conditions: Noninvasive Ventilation
Interventions: OTHER: Interventions in the guideline to infants receiving NIV|OTHER: Usual care to infants receiving NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis
Status: COMPLETED
Conditions: Enthesitis Related Arthritis (ERA)
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Status: RECRUITING
Conditions: Traumatic Injury of the Spinal Cord
Interventions: DRUG: HBO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study III (BLESSIII)
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: Botulinum Toxin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent® Inhalation Aerosol in COPD Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium|DRUG: ipratropium bromide / albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer
Status: RECRUITING
Conditions: Pediatric Cancer|Oncology|Disruptive Behavior
Interventions: BEHAVIORAL: Internet-Based Parent-Child Interaction Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 2-HOBA: Multiple Dosing Study in Healthy Humans
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: 2-HOBA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peri-Operative Testosterone Administration in Primary Hip Arthroscopy
Status: NOT_YET_RECRUITING
Conditions: Femoro Acetabular Impingement
Interventions: DRUG: Nandrolone Decanoate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reinforcement-Based Treatment for Pregnant Drug Abusers
Status: COMPLETED
Conditions: Drug Use Disorders During Pregnancy
Interventions: BEHAVIORAL: Usual RBT (t-RBT)|BEHAVIORAL: Reduced RBT (r-RBT)|BEHAVIORAL: Abbreviated RBT (a-RBT)|BEHAVIORAL: Enhanced RBT (e-RBT)|BEHAVIORAL: Early compliant t-RBT|BEHAVIORAL: Early non-compliant t-RBT|BEHAVIORAL: Early compliant r-RBT|BEHAVIORAL: Early non-compliant r-RBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Subunit Herpes Zoster Vaccine in VZV-Seronegative Organ Transplant Recipients
Status: COMPLETED
Conditions: Varicella Zoster Vaccine
Interventions: BIOLOGICAL: recombinant subunit Herpes zoster vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Daily Wear Comparison of Enhanced and Non-Enhanced Silicone Hydrogel Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon A Experimental Contact Lens|DEVICE: Lotrafilcon A Commercial Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Muscle and Body Temperature Responses During Uphill and Downhill Running
Status: NOT_YET_RECRUITING
Conditions: Body Temperature Changes|Exercise|Blood Pressure
Interventions: PROCEDURE: Uphill running|PROCEDURE: Flatland running|PROCEDURE: Downhill running
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Niraparib vs Niraparib Plus Bevacizumab in Patients With Platinum/Taxane-based Chemotherapy in Advanced Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients
Status: RECRUITING
Conditions: Glioblastoma Multiforme of Brain
Interventions: BIOLOGICAL: Dendritic cell vaccine plus temozolomide chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Hourly Prompts on Reducing Prolonged Sitting at Work
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Hourly prompts to stand delivered by Microsoft Outlook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus Arthritis
Interventions: DRUG: Methylprednisolone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care
Status: NOT_YET_RECRUITING
Conditions: Neurocritical Care|Traumatic Brain Injury|Cerebrovascular Disease|Moderate or Severe Coma
Interventions: PROCEDURE: Enhanced recovery after surgery|PROCEDURE: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a Cow/Human Parainfluenza Virus Vaccine (rB/HPIV3) in Healthy Infants, Children, and Adults
Status: COMPLETED
Conditions: Paramyxoviridae Infections|Virus Diseases
Interventions: BIOLOGICAL: rB/HPIV3|BIOLOGICAL: rB/HPIV3|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Intermittent and Continuous OSI-906 and Weekly Paclitaxel in Patients With Recurrent Epithelial Ovarian Cancer (and Other Solid Tumors)
Status: COMPLETED
Conditions: Ovarian Cancer|Solid Tumors
Interventions: DRUG: OSI-906|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Novel Human Laboratory Paradigm for AUD Medication Screening
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: OTHER: Model 1|OTHER: Model 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise Performance
Status: COMPLETED
Conditions: Energy Metabolism
Interventions: DIETARY_SUPPLEMENT: GAA-creatine|DIETARY_SUPPLEMENT: Creatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intratumoural Administration of Coxsackievirus A21 for the Control of Malignant Melanoma (PXS-X02)
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Coxsackievirus A21
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bortezomib|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: BIOLOGICAL: PRP|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Topical Timolol Combined With Cryotherapy in EGFR Inhibitors-induced Paronychia - a Double-blinded, Intrapatient Left-to-right Controlled Study
Status: COMPLETED
Conditions: Paronychia|Epidermal Growth Factor Receptor Inhibitor
Interventions: DRUG: Timolol maleate 0.5% ophthalmic solution|PROCEDURE: Cryotherapy with liquid nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panda: Evaluation of a Smartphone-based Perioperative Pain Assessment Tool
Status: COMPLETED
Conditions: Acute Post-operative Pain
Interventions: DEVICE: Panda first followed by manual pain assessment|DEVICE: Manual first followed by Panda pain assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Silicone Material Inserts To Treat Burn Scars
Status: WITHDRAWN
Conditions: Burns
Interventions: DEVICE: Pressure garment and silicone insert|DEVICE: Pressure garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Postoperative Modified Trendelenburg Position to Decrease Shoulder Pain After Laparoscopic Hysterectomy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Post Operative Pain|Shoulder Pain|Gynecologic Disease
Interventions: PROCEDURE: Postoperative Modified Trendelenburg position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Versus Placebo for Blood to Reduce Perioperative Bleeding Post-liver Resection
Status: COMPLETED
Conditions: Cancer|Tumour|Surgery
Interventions: DRUG: No tranexamic acid|DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Management of Systemic-Pulmonary Collateral Blood Flow in Cyanotic Children During Cardiopulmonary Bypass - Pilot Study
Status: UNKNOWN
Conditions: Heart Defects, Congenital
Interventions: DRUG: pH Stat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypnotherapy in Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Hypnotherapy (HYP)|BEHAVIORAL: Relaxation training (RT)|OTHER: Care as usual (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis
Status: COMPLETED
Conditions: Encephalitis
Interventions: DRUG: Immunoglobulins, Intravenous (Privigen)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LT4/LT3 Combination Therapy Versus LT4 Monotherapy in Patients With Autoimmune Hypothyroidism.
Status: RECRUITING
Conditions: Autoimmune Hypothyroidism
Interventions: DRUG: LT3 (liothyronine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLL
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: pentostatin|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Augmentation With Curcumin Combined With Xenograft
Status: NOT_YET_RECRUITING
Conditions: Horizontal Alveolar Bone Loss
Interventions: DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of QVAR on Lung Functioning in Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: COPD
Interventions: DRUG: HFA-134A Beclomethasone DIpropionate (QVAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FTY720 in Patients With Relapsing Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: FTY720|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT