pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Muscle Energy Technique|OTHER: Sacral Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetyl Cysteine: the Effectiveness and Safety in a Cohort of Pediatric Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-ERCP High Carbohydrate Drinks Improve Patients Recovery
Status: COMPLETED
Conditions: Complication
Interventions: PROCEDURE: 400ml high carbohydrate liquid diet before ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of MCS110 Given With Carboplatin and Gemcitabine in Advanced Triple Negative Breast Cancer (TNBC)
Status: COMPLETED
Conditions: Advanced Triple Negative Breast Cancer (TNBC) With High TAMs
Interventions: DRUG: MCS110|DRUG: carboplatin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEMAND - DEgenerative Meniscal Tears - Arthroscopy vs. Dedicated Exercise
Status: WITHDRAWN
Conditions: Degenerative Meniscal Tears|Knee Osteoarthritis
Interventions: PROCEDURE: Arthroscopy|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis.
Status: UNKNOWN
Conditions: Acute Pancreatitis|Hypertriglyceridemia
Interventions: DRUG: Insulin|DEVICE: plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: KX2-391 Ointment 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reiki for Cancer: Pain, Anxiety, and Stress
Status: COMPLETED
Conditions: Therapeutic Touch|Cancer
Interventions: OTHER: Reiki|OTHER: Sham Reiki|OTHER: Progressive Relaxation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: HLT Transcatheter Aortic Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Careseng 1370 for Chemotherapy-Induced Myelosuppression
Status: WITHDRAWN
Conditions: Chemotherapy-Induced Myelosuppression
Interventions: DRUG: Careseng 1370|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain
Status: TERMINATED
Conditions: Neurotoxicity|Pain|Breast Cancer
Interventions: DRUG: D-cycloserine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Statin Medications on Mental Processes, Behavior, and Serotonin Levels
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: 40 mg Pravastatin (Pravachol)|DRUG: 20 mg Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Different Chemotherapy Types in Chinese Patients With Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Skin Preparation Evaluation
Status: COMPLETED
Conditions: Topical Antisepsis
Interventions: DRUG: Chlorhexidine gluconate|DRUG: ChloraPrep One Step|DRUG: Sterile saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: (CB-01-02/02) Randomized Placebo Controlled Trial of Budesonide-multi-matrix System (MMX™) 6 mg and 9 mg in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Blood sampling, endoscopy|DRUG: Budesonide MMX® 6 mg|DRUG: Budesonide MMX® 9 mg|DRUG: Entocort EC® 3 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation-hormone and Docetaxel VS Radiation-hormone in Patients With High-Risk Localized Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer Stage III|Prostate Cancer Stage IV
Interventions: DRUG: Docetaxel|BIOLOGICAL: Hormone and radiation therapy|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Squamous Cell Carcinoma In Situ|Vulvar High Grade Squamous Intraepithelial Lesion
Interventions: DRUG: Cyclophosphamide|DRUG: Indomethacin|BIOLOGICAL: IRX-2|OTHER: Laboratory Biomarker Analysis|DIETARY_SUPPLEMENT: Multivitamin|DRUG: Omeprazole|OTHER: Placebo|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics to Treat "Inflammatory Depression"
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Revlimid|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 506U78 in Treating Patients With Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Small Intestine Lymphoma|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma|Stage I Mycosis Fungoides/Sezary Syndrome|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma|Stage II Mycosis Fungoides/Sezary Syndrome|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome
Interventions: DRUG: nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diet on the Immune System in Patients With Stage III-IV Melanoma Receiving Immunotherapy, DIET Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Melanoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Unresectable Melanoma
Interventions: OTHER: Dietary Intervention|OTHER: Dietary Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Study of Single Agent Oral RG7388 in Patients With Polycythemia Vera and Essential Thrombocythemia
Status: COMPLETED
Conditions: Polycythemia Vera|Essential Thrombocythemia
Interventions: DRUG: RG7388|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of 68Ga-PSMA PET Data With Magnetic Resonance Spectroscopy Data (MRS) for Evaluating Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PET/MR scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endothelial Dysfunction and Subclinical Atheromatosis in Chronic HCV Infection. Response to DAA Agents.
Status: UNKNOWN
Conditions: Hepatitis C|Cardiovascular Diseases
Interventions: OTHER: Cardiovascular risk in HCV patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Sarcopenia and Osteoporosis in the Patients With Hemophilia
Status: COMPLETED
Conditions: Sarcopenia|Hemophilia|Osteoporosis, Osteopenia|Hemophilic Arthropathy
Interventions: DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry (DXA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma
Status: COMPLETED
Conditions: Endometrial Cancer|Uterine Cancer|Ovarian Cancer|Carcinosarcoma
Interventions: DRUG: Paclitaxel|DRUG: 300mg DKN-01|DRUG: 600mg DKN-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Proportionality of Different Dose Strengths of Linagliptin Tablets After Oral Administration to Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin, low dose|DRUG: Linagliptin, medium dose|DRUG: Linagliptin, high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCB Compared Stenting in Popliteal Lesions
Status: UNKNOWN
Conditions: Popliteal Stenosis|Popliteal Artery Occlusion|Diabetes
Interventions: DEVICE: DCB angioplasty (Orchid, Acotec Scientific Co. Ltd.)|DEVICE: Stent (Maris,Medtronic.USA or Sinus/Supera, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Nano-S1
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: NANOS1 , argent colloïdal ,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Regimens of Misoprostol in Retained Placenta
Status: COMPLETED
Conditions: Postpartum Haemorrhage|Retained Placenta
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC
Status: RECRUITING
Conditions: Sentinel Lymph Node|Head and Neck Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: peritumoral microbubbles and contrast-enhanced ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MR Pulmonary Angiography to Replace CT Pulmonary Angiography for Patients With a Suspicion of a Pulmonary Embolism
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism|Radiation Exposure
Interventions: DIAGNOSTIC_TEST: MRPA|DIAGNOSTIC_TEST: CPTA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride Varnish on Remineralization of White Spot Lesion in Primary Teeth
Status: COMPLETED
Conditions: White Spot Lesion
Interventions: DRUG: CPP-ACP|DRUG: Duraphat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive Assistance
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: HMW-HA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Comparator in the Treatment of Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Olanzapine Hydrochloride|DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PRolaCT - Three Prolactinoma RCTs
Status: RECRUITING
Conditions: Prolactinoma|Prolactin-Producing Pituitary Tumor
Interventions: PROCEDURE: Endoscopic trans-sphenoidal adenoma resection|DRUG: Dopamine Agonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chemotherapy Combination With Autologous Cell Immunotherapy in the Advanced Lung Cancer
Status: UNKNOWN
Conditions: IIIB/IIIC/IV Lung Cancer
Interventions: DRUG: Docetaxel|BIOLOGICAL: PD1-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2157GCCC:Phase 1 of Calaspargase Pegol-mknl w/ Cytarabine and Idarubicin in Newly Dx AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Calaspargase pegol-mknl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Time Restricted Eating on Patients With Coronary Artery Disease (CAD) Undergoing Cardiac Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: ICR (Intensive Cardiac Rehabilitation)|BEHAVIORAL: ICR x TRE (Intensive Cardiac Rehabilitation x Time-Restricted Eating)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microelectrode Brain-Machine Interface for Individuals With Tetraplegia
Status: TERMINATED
Conditions: Tetraplegia|Spinal Cord Injury
Interventions: DEVICE: Implantation of NeuroPort Arrays in the motor cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of DA-2803 in Chronic Hepatitis B Patients
Status: RECRUITING
Conditions: Hepatitis B
Interventions: DRUG: DA-2803|DRUG: DA-2803-R|DRUG: Placebo of DA-2803|DRUG: Placebo of DA-2803-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Medical Treatment for Nephropathy Caused by Type 2 Diabetes With Hypertension
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: DRUG: Intensive therapy Valsartan,Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of Recombinant Meningococcal Group B Vaccine (E.Coli)
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Recombinant Meningococcal Group B Vaccine (E. Coli) (low-dose)|BIOLOGICAL: Recombinant Meningococcal Group B Vaccine (E. Coli) (hign-dose)|BIOLOGICAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Korean Multicenter Registry of ELUVIA Stent for Femoropopliteal Artery Disease
Status: COMPLETED
Conditions: Symptomatic Peripheral Artery Disease With Femoropopliteal Lesions|Moderate or Severe Claudication (Rutherford Category 2 or 3)|Critical Limb Ischemia (Rutherford Category 4 or 5)
Interventions: DEVICE: Implantation of Eluvia stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Clinical Trial of Hydrocortisone Augmentation of Prolonged Exposure
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Hydrocortisone augmented Prolonged Exposure Therapy|OTHER: Prolonged exposure therapy with placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function
Status: COMPLETED
Conditions: Dietary Habits|Endotoxemia
Interventions: OTHER: Dietary intervention 1|OTHER: Dietary Intervention 2|OTHER: Dietary Intervention 3|OTHER: Dietary Intervention 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Goal-directed Fluid Therapy and Physiological Changes Following One-lung Ventilation
Status: UNKNOWN
Conditions: Therapy Adverse Effect
Interventions: OTHER: SV maximization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluation of GSK Biologicals' Pandemic Influenza Vaccine
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: GSK's candidate influenza vaccine 1562902A|BIOLOGICAL: FluarixTM|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EUS-B-FNA vs EUS-FNA for Left Adrenal Gland Analysis in Lung Cancer Patients
Status: UNKNOWN
Conditions: Suspected Left Adrenal Gland Metastasis in Lung Cancer
Interventions: PROCEDURE: EUS-B-FNA followed by EUS-FNA for LAG analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Parenteral Nutrition Associated Liver Disease: Early Markers and Therapy Wih Enteral Omega-3 Supplementation
Status: UNKNOWN
Conditions: Parenteral Nutrition Associated Liver Disease
Interventions: DRUG: Lovaza (fish oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Oxycodone and PF614 Co-Administered With Nafamostat
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: PF614 solution|DRUG: Naltrexone Hydrochloride|DRUG: Nafamostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib Citrate, Lenalidomide, Dexamethasone, and Daratumumab in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BreEStim and tDCS for Neuropathic Pain Management - Healthy Subjects
Status: COMPLETED
Conditions: Pain Management
Interventions: DEVICE: BreEStim|DEVICE: tDCS active|DEVICE: tDCS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vibe First In Human Study for the Assessment of Safety and Initial Performance of the Vibe Delivery System in Subjects With Idiopathic Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: Vibe Delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transducer Selection in the Speed and Quality of Image Acquisition in FAST Exams
Status: COMPLETED
Conditions: Diagnostic Abdominal Ultrasonography|Trauma Injury
Interventions: DIAGNOSTIC_TEST: Focused Assessment of Sonography for Trauma Exam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chidamide Combined With VDDT Regimen in the Relapse and Refractory Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Chidamide|DRUG: Vinorelbine|DRUG: Liposomal Doxorubicin or mitoxantrone|DRUG: Dexamethasone|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Hemopatch in Reducing Seroma Related Complications Following Axillary Lymph Node Dissection: a Pilot Study
Status: COMPLETED
Conditions: Axillary Lymph Node Dissection|ALND|Axillary Clearance|Seroma
Interventions: DEVICE: Hemopatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of a Pre-meal Protein Drink With or Without Added Amino Acids at a Subsequent Composite Meal
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Satiety Response
Interventions: DIETARY_SUPPLEMENT: Protein drink|DIETARY_SUPPLEMENT: Reference meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Glioblastoma With Primitive Neuronal Component|Gliosarcoma|Malignant Glioma|Oligodendroglial Component Present
Interventions: DRUG: Plerixafor|DRUG: Temozolomide|RADIATION: Whole-Brain Radiotherapy (WBRT)|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Reduction With Intranasal Medications for Extremity Injuries
Status: COMPLETED
Conditions: Pain|Traumatic Limb Injury
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining tsDCS and Exoskeleton Gait Training on Spinal Excitability in SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: cathode tsDCS|DEVICE: Ekso|DEVICE: anode tsDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tracheal Intubation With Collar Immobilisation : a Comparison of Glidescope and Fastrach
Status: COMPLETED
Conditions: Injury of Cervical Spine
Interventions: DEVICE: Glidescope|DEVICE: ILMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial
Status: RECRUITING
Conditions: Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Ipatasertib|PROCEDURE: Magnetic Resonance Imaging|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effect of Virtual Reality Glasses
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Cancer|Chemotherapy|Virtual Reality|Treatment Compliance
Interventions: DEVICE: Weight: 414g Size: 19.5cm x 14cm x 11cm Compatibility: Android and iOS VR Box 3.0 3D Virtual Reality Glasses Has the Feature of Fixation with Headband It has a lens mechanism tha
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pentostatin, Cyclophosphamide Plus Rituximab (PCR) for the Therapy of Poor-Prognosis Chronic Graft-Versus-Host Disease
Status: WITHDRAWN
Conditions: Active Chronic Graft Versus Host Disease
Interventions: DRUG: Pentostatin; Cyclophosphamide; Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Monthly Recombinant Factor XIII Replacement Therapy in Subjects With Congenital Factor XIII Deficiency: An Extension to Trial F13CD-1725
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FXIII Deficiency
Interventions: DRUG: catridecacog
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preventive Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors
Status: UNKNOWN
Conditions: Drug-Related Side Effects and Adverse Reactions|Epidermal Growth Factor
Interventions: DRUG: Repair Control EGF®|DRUG: Cream without rhEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study To Evaluate PF-05175157 In Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05175157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing General Anesthesia, General Anesthesia With ESP Block or TLIP Block in Patients Undergoing Lumbar Surgeries
Status: RECRUITING
Conditions: Lumbar Disc Herniation|Lumbar Discogenic Pain|Lumbar Spinal Stenosis|Failed Back Surgery Syndrome
Interventions: PROCEDURE: regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobic Exercise and Diet on Anthropometric and Hematological Measurements in Obese Anemic Women
Status: UNKNOWN
Conditions: Obesity|Iron Deficiency Anemia
Interventions: COMBINATION_PRODUCT: combination of aerobic exercise and healthy diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taxonomic and Functional Composition of the Intestinal Microbiome: a Predictor of Rapid Cognitive Decline in Patients With Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease|Intestinal Microbiota
Interventions: PROCEDURE: Fecal sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Adaption Training-Effectiveness in Real-world Settings and Mechanism of Action (CAT-EM)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Adaptation Training|BEHAVIORAL: Community Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Liquid 13-cis-retinoic Acid (13-CRA)
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Liquid 13-Cis Retinoic Acid|DRUG: Extracted capsules 13-CRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
Status: TERMINATED
Conditions: Critical Limb Ischemia|Arterial Occlusive Disease|Pain|Ischemia
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Study of the Functioning of Magnocellular Visual Pathway in Regular Cannabis Users
Status: COMPLETED
Conditions: Cannabis Use
Interventions: OTHER: Electroretinography|OTHER: Contrast sensitivity test during Electroencephalography|OTHER: Visual simultaneity test during Electroencephalography|OTHER: Face perception test during Electroencephalography|OTHER: CAST (cannabis abuse screening test)|OTHER: PANSS (Positive And Negative Symptoms Scale) test|OTHER: Delayed Matching to Sample (DMS) test|OTHER: Spatial Working Memory (SWM) test|OTHER: Rapid Visual Information Processing (RVP) test|OTHER: Test for attentional performance (TAP) / Divided Attention|OTHER: Collection of saliva sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma (MK-3795-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: ccRCC|RCC|Kidney Cancer|Clear Cell Renal Cell Carcinoma|Renal Cell Carcinoma
Interventions: DRUG: MK-3795|DRUG: Nivolumab|DRUG: Cabozantinib|DRUG: Bezlutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of Human Monoclonal Antibodies, BRII-196 and BRII-198
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: BRII-196 and BRII-198|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing in Elderly Women With Recurrent UTI
Status: COMPLETED
Conditions: Recurrent Urinary Tract Infection
Interventions: DRUG: Methenamine Hippurate 1000 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer
Status: RECRUITING
Conditions: Locally Advanced Colon Cancer
Interventions: DRUG: capecitabine plus oxaliplatin before and after surgery|DRUG: capecitabine plus oxaliplatin after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Respicure® (Resveratrol / Quercetin) in the Management of Respiratory Conditions Including Asthma,COPD and Long COVID.
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|Long COVID
Interventions: OTHER: Respicure®|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training
Status: NOT_YET_RECRUITING
Conditions: Behavioral Problem|Irritable Mood|Parenting|Stress
Interventions: BEHAVIORAL: Brief Behavioral Parenting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine, Cytarabine, and G-CSF in Treating Patients With Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|DRUG: clofarabine|DRUG: cytarabine|GENETIC: microarray analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms
Status: RECRUITING
Conditions: Scleroderma, Systemic
Interventions: DRUG: Avenciguat (BI 685509)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thymoglobulin: Presence and Affect in the Central Lymphatic Compartment
Status: COMPLETED
Conditions: Renal Transplantation|Immunosuppression
Interventions: DRUG: anti-thymocyte globulin|DRUG: anti-thymocyte globulin|DRUG: anti-thymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Steroid Refractory Gastro-intestinal Acute GVHD afteR AllogeneiC HSCT With fEcal Microbiota tranSfer
Status: COMPLETED
Conditions: Fecal Microbiota Transplantation
Interventions: DRUG: fecal microbiota transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pemetrexed and Cisplatin, in Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|RADIATION: Thoracic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsed-Dyed Laser on Scar Formation
Status: COMPLETED
Conditions: Scars
Interventions: DEVICE: Treatment of 1/2 of skin graft with pulsed-dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Periodontal Therapy on Gingival Crevicular Fluid NLRP3,Caspase-1,IL-1β Levels in Children With Gingivitis
Status: RECRUITING
Conditions: Gingivitis
Interventions: PROCEDURE: Periodontal theraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D
Status: COMPLETED
Conditions: Chronic Kidney Disease|Secondary Hyperparathyroidism|Hemodialysis
Interventions: DRUG: Paricalcitol|DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Bintrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline as an Adjunctive Therapy for Schizophrenia: a Randomized Controlled Study
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Minocycline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Abraxane, Cisplatin and 5-Fluorouracil Along With Chemoradiotherapy in Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: ABI-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Efficacy and Safety of Aliskiren (150mg & 300mg) Administered Alone and in Combo With Valsartan (160mg and 320mg) in Patients With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Psychosocial Stimulation and Cash on Children's Development and Behaviour
Status: UNKNOWN
Conditions: Child Development|Child Behavior
Interventions: OTHER: Psychosocial stimulation (PS)|OTHER: Government Intervention (UCT+HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: SBRT Followed by Neoadjuvant Chemoimmunotherapy of Sindilizumab Plus Docetaxel and Cisplatin for Locoregionally Advanced Squamous Carcinoma of Oral Cavity and Oropharynx
Status: RECRUITING
Conditions: SBRT
Interventions: COMBINATION_PRODUCT: SBRT+chemoimmunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index Value Changes During Induction and Surgical Decompression in Head Injury Patients
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Bispectral Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality-Assisted Cognitive Behavioral Therapy for Alcohol Dependence (CRAVR)
Status: UNKNOWN
Conditions: Alcohol Dependence, in Remission|Addiction, Alcohol
Interventions: BEHAVIORAL: Virtual Reality Cognitive Behavioral Therapy (CRAVR)|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: My Stroke Team (MYST): Stroke App Pilot Study
Status: COMPLETED
Conditions: Stroke|Comorbidity|Chronic Disease
Interventions: OTHER: Strengthening Community-Based Stroke Care: A Pilot Study of a Community Navigation and Rehabilitation Intervention that Includes a Mobile Health Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial Evaluating the Efficacy, Safety, & Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Centanafadine SR|OTHER: Placebo|DRUG: Centanafadine SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics of KD101 in Healthy Male Subjects
Status: COMPLETED
Conditions: Drug Toxicity
Interventions: DRUG: KD101|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 2 Study to Evaluate the Dose and Pharmacodynamic Efficacy of Sialic Acid-Extended Release (SA-ER) Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy
Status: COMPLETED
Conditions: GNE Myopathy|Hereditary Inclusion Body Myopathy
Interventions: DRUG: Sialic Acid Extended Release (SA-ER)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Guide-wire G-240 to a Combination of a Flexible/Hydrophil and a Nitinol Guide Wire
Status: COMPLETED
Conditions: Other Specified Diseases of Biliary Tract
Interventions: DEVICE: Guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Global Study to Compare the Effects of Fulvestrant and Arimidex in a Subset of Patients With Breast Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Receptor Positive Breast Cancer
Interventions: DRUG: faslodex 500mg|DRUG: arimidex 1mg|DRUG: faslodex dummy|DRUG: arimidex dummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Image Quality for Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound FLOW Imaging
Status: RECRUITING
Conditions: Carotid Artery Stenosis
Interventions: DIAGNOSTIC_TEST: Conventional duplex|DIAGNOSTIC_TEST: Ultrasound-based flow imaging using plane wave imaging|DIAGNOSTIC_TEST: Ultrasound-based flow imaging using cascaded wave imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Bioavailability Study of Two Different Sources of Eslicarbazepine Acetate
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: BIA 2-093
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed/Cisplatin Intercalating Gefitinib Treating EGFR Wild NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: pemetrexed/cisplatin intercalating gefitinib|DRUG: pemetrexed/cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism|Hypogonadism, Male
Interventions: DRUG: Nanomilled testosterone|DRUG: Nanomilled dutasteride|DRUG: commercially available dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Boindicator as Monitoring Tool for Oyster Norovirus Outbreak
Status: WITHDRAWN
Conditions: Gastroenteritis Norovirus
Interventions: OTHER: Oyster consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Mineral Water of Vichy and the Urinary Alkalization: A Study of the Dose - Effect of Bicarbonate Salt Water on the Urinary pH in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Vichy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effect of ASP1707 on the Bodies of Healthy Male Subjects After a Single Dose of Radioactive ASP1707
Status: COMPLETED
Conditions: Pharmacokinetics of ASP1707
Interventions: DRUG: 14C-labeled ASP1707
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy for Participants With Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large Cell, Diffuse
Interventions: DRUG: enzastaurin|DRUG: gemcitabine|DRUG: rituximab|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does MI Have a Therapeutic Role in Arthroscopic Rotator Cuff Repair?
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears|Motor Imagery|Muscle Activity|Atrophy, Muscular|Patient Satisfaction|Kinesiophobia|Shoulder Pain
Interventions: BEHAVIORAL: Motor Imagery|BEHAVIORAL: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of MDI Treatment With an Optimization Algorithm Adjusting Basal-Bolus Parameters in Children and Adolescents With Type 1 Diabetes at a Diabetes Camp
Status: COMPLETED
Conditions: Diabete Mellitus|Diabetes Mellitus, Type 1
Interventions: OTHER: Multiple Daily Injections: Slow acting insulin and Rapid acting insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge
Status: COMPLETED
Conditions: Heart Failure|Copd|Liver Failure|Diabetes Mellitus|Cancer|End Stage Renal Disease
Interventions: OTHER: Medically Tailored Meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dose-escalation Study of Oral CX-4945
Status: UNKNOWN
Conditions: Advanced Solid Tumors|Breast Cancer|Inflammatory Breast Cancer|Castleman's Disease|Multiple Myeloma
Interventions: DRUG: CX-4945 oral formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Nursing Intervention in Kidney Transplant Recipients Adherence
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplant; Complications
Interventions: OTHER: Nursing information with a Protocol|OTHER: Usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE