pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Nerve Block.
Status: COMPLETED
Conditions: Bupivacaine|Dexamethasone|Magnesıum Sulphate|Adjuvant
Interventions: DRUG: Bupivacaine + dexamethasone|DRUG: Bupivacaine + magnesium sulphate|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurotoxin and Physical Therapy
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: Botox injection|BEHAVIORAL: Physical Therapy|PROCEDURE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) for Post COVID-19 Fatigue
Status: COMPLETED
Conditions: Post Covid-19 Patients
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Behavioral Symptoms in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Psychosis|Agitation
Interventions: DRUG: Haloperidol-Haloperidol|DRUG: Haloperidol-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Effect of Two Facial Sunscreens in Improving Wrinkles, Fine Lines and Melasma in Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Sunscreen Color tone 2.0|OTHER: Sunscreen Color tone 3.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EEG Spectrogram-guided vs. Index-guided Anesthesia for Craniotomy
Status: RECRUITING
Conditions: Craniotomy
Interventions: DEVICE: EEG spectrogram|DEVICE: Bispectral index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Safety and Efficacy of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Ivermectin|DRUG: Ivermectin (reference)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Investigation of the Efficacy and Safety of Uracyst® Versus Placebo in Patients With Interstitial Cystitis/Painful Bladder Syndrome.
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DEVICE: placebo|DEVICE: Uracyst
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up
Status: UNKNOWN
Conditions: Coronary Angiography
Interventions: DRUG: Statin, aspirin|DRUG: Dipyridamole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Lymphoblastic Lymphoma|Acute Leukemia
Interventions: OTHER: Educational Intervention|OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early or Late Cord Clamping in the Depressed Neonate
Status: COMPLETED
Conditions: Neonatal Disorder|Asphyxia Neonatorum
Interventions: PROCEDURE: Early (≤ 60 seconds) cord clamping|PROCEDURE: Delayed (≥ 180 seconds) cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome
Status: RECRUITING
Conditions: Retinoblastoma
Interventions: DRUG: Melphalan or Melphalan + Topotecan|DRUG: etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy|DRUG: Carboplatin administered on Day 1|DEVICE: Thermotherapy (local treatment)|DEVICE: Cryotherapy (local treatment)|DEVICE: Iodine-125 plaques (local treatment)|DRUG: Intravitreal Melphalan chemotherapy injections (local treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Fish Oil and Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: omega-3 polyunsaturated fatty acids ( EPA+DHA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zenoctil in Reducing Body Weight
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Zenoctil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Musculoskeletal Ultrasound for Diagnosis of Shoulder Dislocation Reduction
Status: UNKNOWN
Conditions: Ultrasound|Shoulder Dislocation|Musculoskeletal Injury
Interventions: DIAGNOSTIC_TEST: Point of care ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Observational, Bivariate Analysis of Clinical Big Data in Patients With Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Progression-free Survival Was Defined From Date of Surgery to Disease Progression Post-surgery or Death or Last Follow-up|Overall Survival Was Defined as Time From Surgery to Death From Any Cause or Last Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension
Status: UNKNOWN
Conditions: Hypertension, Resistant to Conventional Therapy|Essential Hypertension
Interventions: DRUG: Losartan and hydrochlorothiazide|DRUG: Hydrochlorothiazide switched over with Losartan at 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Switch to Aripiprazole on Health and Smoking Parameters in Patients With Schizophrenia: A Pilot Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Diabetes Text Messaging (DB-TEXT) Combined With Peer Support Education in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Personalized Diabetes Text Messaging (DB-TEXT) combined with Peer Support Education|BEHAVIORAL: Personalized Diabetes Text Messaging (DB-TEXT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Hormone-Sensitive Prostate Cancer
Interventions: BIOLOGICAL: PROSTVAC-V|BIOLOGICAL: PROSTVAC-F|DRUG: Nivolumab|DRUG: Ipilimumab|BIOLOGICAL: Neoantigen DNA vaccine|DEVICE: TriGrid Delivery System|PROCEDURE: Tumor biopsy|PROCEDURE: Peripheral blood|PROCEDURE: Fecal samples|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence and Wear Study of Mylan Fentanyl Transdermal System 25 µg/h and Mylan Fentanyl Transdermal System
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Scotch Duct Tape (3M)|DRUG: Duragesic 25 mcg/h + Scotch Duct Tape (3M)|DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Blenderm Clear Plastic Surgical Tape (3M)|DRUG: Duragesic 25 mcg/h + Blenderm Clear Plastic Surgical Tape (3M)|DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Microfoam Tape (3M)|DRUG: Duragesic 25 mcg/h + Microfoam Tape (3M)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRM-151 in the Prevention of Scarring Following Trabeculectomy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: PRM-151|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Paracetamol on Opicapone Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIA 9-1067|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Immunodeficiency Virus (HIV), Arterial Dysfunction, Lipids, Lovaza (HALO) Trial
Status: COMPLETED
Conditions: Cardiovascular Disease|HIV Infection
Interventions: DRUG: Lovaza|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Chemotherapeutic Agent Toxicity|Fatigue|Lung Cancer|Musculoskeletal Complications
Interventions: DRUG: carboplatin|DRUG: vinorelbine tartrate|OTHER: neuromuscular electrical stimulation|OTHER: physiologic testing|PROCEDURE: fatigue assessment and management|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Monosodium Glutamate Supplementation on Gastric Emptying and Postprandial Nitrogen Kinetics
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MSg supplementation|DIETARY_SUPPLEMENT: NaCl supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Peri-operative Supplemental Oxygen in Wound Infection After Appendectomy
Status: COMPLETED
Conditions: Perioperative Hyperoxygenation|Wound Infection
Interventions: DRUG: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: COVAG - Covid-19 Antigen Study - the Diagnostic Efficacy of SARS-CoV-2 Rapid Detection Tests
Status: COMPLETED
Conditions: COVID-19|SARS-CoV2 Infection|SARS (Disease)
Interventions: DEVICE: 3 nasopharyngeal swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate
Status: TERMINATED
Conditions: Non-infectious Intermediate and Posterior Uveitis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLX2853 in Combination With Abiraterone Acetate and Prednisone and in Combination With Olaparib in Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: PLX2853|DRUG: Olaparib|DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Injections Treating Birch Pollen Induced Allergic Rhinitis.
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Hay Fever|Pollen Allergy|Allergic Rhinitis
Interventions: DRUG: MethylPREDNISolone 40 Mg/mL Injectable Suspension|DRUG: NaCl 9 MG/ML Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of an Ultra-rapid BRCA1/2 Status Screening Test in Theranostic Indication: Performance and Interest for Patients and Practitioners
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Questionnaires|OTHER: Communication of the results of the BRCA1/2 ultra rapid test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Emergence Delirium: Remimazolam vs Sevoflurane Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium
Interventions: DRUG: Remimazolam|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine the Maximum Tolerated Dose of BIBW 2992 (Afatinib) When Combined With Cisplatin/Paclitaxel or Cisplatin/5-FU in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BIBW 2992|DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Safety of Subcutaneous Administration of Affitope AD01 in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: AFFITOPE AD01|BIOLOGICAL: AFFITOPE AD01 adjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study of Safety and Efficacy of Everolimus With Low Dose Tacrolimus to Mycophenolate Mofetil With Standard Dose Tacrolimus in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Everolimus and tacrolimus|DRUG: mycophenolate mofetil and tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Use|Prolapse; Female|Incontinence
Interventions: OTHER: Standard opioid prescribing|OTHER: Restrictive opioid prescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Convection-Enhanced Delivery of 124I-Omburtamab for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
Status: COMPLETED
Conditions: Brain Cancer|Brain Stem Glioma
Interventions: DRUG: Radioactive iodine-labeled monoclonal antibody omburtamab|RADIATION: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vismodegib in Treating Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease
Status: TERMINATED
Conditions: Chronic Graft Versus Host Disease
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Localized Primary Osteoarthritis of Both Hips (Diagnosis)|Osteoarthritis, Hip
Interventions: DRUG: Dexamethasone|DRUG: Normal Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Infliximab|BIOLOGICAL: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Radiotherapy for Oligometastasis of Lung Adenocarcinoma With Negative Driver Gene
Status: UNKNOWN
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Bevacizumab Injection|RADIATION: chest radiation|DRUG: concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)
Status: RECRUITING
Conditions: Covid19
Interventions: BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab|BIOLOGICAL: sotrovimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Different Treatment Modalities in Individuals With Knee Osteoarthritis
Status: RECRUITING
Conditions: Gonarthrosis; Primary
Interventions: OTHER: Virtual Reality Exercises|OTHER: Virtual Reality Exercises and Kinesiotaping|OTHER: Virtual Reality Exercises and Valgus Orthoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Zinc Suplementation on Serum Hemosystein Level in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Failure
Interventions: DRUG: Zinc Supplement|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microfracture With/Without Collagen Augmentation in Patients Undergoing High Tibial Osteotomy
Status: UNKNOWN
Conditions: Collagen Augmentation
Interventions: PROCEDURE: Microfracture without Collagen Augmentation|PROCEDURE: Microfracture with Collagen Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Raltitrexed Plug Compare With Taxol Second-line Treatment for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: taxel plus raltitrexed|DRUG: taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of an Algorithm to Denoise HFNO-generated Tracheal Sound
Status: RECRUITING
Conditions: Endoscopy, Gastrointestinal|Sedation, Conscious
Interventions: DEVICE: High flow nasal oxygen fist|DEVICE: High flow nasal oxygen later
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Telerehabilitation Exercise Program on Maternal Glycemic Control
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: Telerehabilitation exercise program|OTHER: Routine medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With AML Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: gemtuzumab ozogamicin (GO)|DRUG: Daunorubicin|PROCEDURE: Autologous HCT|PROCEDURE: Allogeneic HCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Advanced Cancer and Liver Dysfunction
Status: COMPLETED
Conditions: Hepatic Complications|Malignant Neoplasm
Interventions: DRUG: bortezomib|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study In Patients With Depression Not Responding to Selective Serotonin Re-uptake Inhibitors
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: 323U66 (Bupropion Hydrochloride Sustained Release)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen
Status: ACTIVE_NOT_RECRUITING
Conditions: Patency of the Ductus Arteriosus|Acetaminophen|Extreme Prematurity
Interventions: DRUG: Acetaminophen|DRUG: NACL 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic on Visceral Fat Accumulation
Status: UNKNOWN
Conditions: Obesity|Intra-Abdominal Fat|Subcutaneous Fat, Abdominal
Interventions: DIETARY_SUPPLEMENT: Active Probiotic|DIETARY_SUPPLEMENT: Inactivated probiotic|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: APG-2575 Single Agent or in Combination With Ibrutinib or Rituximab in Patients With Waldenström Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: APG2575 400 mg|DRUG: APG2575 600 mg|DRUG: APG2575 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation
Status: UNKNOWN
Conditions: Intubation, Intratracheal
Interventions: PROCEDURE: Video Laryngoscopy|PROCEDURE: Direct Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BMS-986020|DRUG: Placebo matching with BMS-986020
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Infections and Unexplained Infertility
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DIAGNOSTIC_TEST: NK cell analysis|DIAGNOSTIC_TEST: Herpesvirus detection|DIAGNOSTIC_TEST: sHLA-G analysis|DIAGNOSTIC_TEST: HLA-G 14bp INS/DEL typing|DIAGNOSTIC_TEST: sHLA-E analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glucocorticoid Therapy Impact on the Inflammatory Response and Clinical Evolution in Patients With Severe Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis, Viral
Interventions: DRUG: Glucocorticoids|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Trastuzumab and Etoposide for Her2 Positive Breast Cancer
Status: TERMINATED
Conditions: HER-2 Positive Metastatic Breast Cancer
Interventions: DRUG: Etoposide|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PALONOSETRON X FOSAPREPITANT IN PONV
Status: UNKNOWN
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: Palonosetron|DRUG: Fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Caregiver Connections Via Technology for Patients With Alzheimer's and Other Types of Dementia
Status: WITHDRAWN
Conditions: Caregiver Stress|Dementia|Alzheimer Dementia|Lewy Body Dementia|Parkinson Disease Dementia|Frontotemporal Dementia
Interventions: BEHAVIORAL: Algorithm|BEHAVIORAL: Random Match
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Water Immersion and Polyp Detection: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Adenoma|Colonic Neoplasms
Interventions: PROCEDURE: Water Infusion first|PROCEDURE: CO2 Insufflation First
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Determining the Effect of Street Play Intervention on Children's Play Tendencies and Social Problem Solving Levels
Status: RECRUITING
Conditions: Child Behavior|Child, Only|Playing Role|Play Role|Problem;Learning|Nursing Caries
Interventions: BEHAVIORAL: Street Games Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using Imaging to Assess Effects of THC on Brain Activity
Status: COMPLETED
Conditions: Intoxication Alcohol|Intoxication THC|Intoxication Combined Alcohol THC
Interventions: DRUG: Dronabinol|DRUG: Ethanol|DRUG: Placebo dronabinol|DRUG: Placebo ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Cancer|Neoplasms, Lung|Neoplasms, Pulmonary
Interventions: DRUG: talabostat|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Participants With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Revefenacin|DRUG: Placebo|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of the HCV Protease Inhibitor Boceprevir and the HIV Integrase Inhibitor Raltegravir
Status: COMPLETED
Conditions: HIV Infections|HCV Infections
Interventions: DRUG: boceprevir|DRUG: raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isovue in Peripheral Digital Subtraction Angiography (DSA)
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: DRUG: iopamidol|DRUG: iodixanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapies for Treatment-Resistant Panic Disorder Symptoms
Status: COMPLETED
Conditions: Panic Disorder
Interventions: DRUG: Clonazepam|DRUG: Sertraline|BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib (Celebrex) in the Management of Acute Renal Colic
Status: WITHDRAWN
Conditions: Ureteral Calculi
Interventions: DRUG: celecoxib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wolf 24 F vs. Storz 28 F Laser Sheath Size for HoLEP
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy
Interventions: DEVICE: Richard Wolf 24F Laser scope|DEVICE: Karl Storz 28F Laser Scope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Arterial Embolization for Men Starting Hormones for Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Adenocarcinoma|Obesity, Morbid
Interventions: DEVICE: Bead Block 300-500 um|BEHAVIORAL: Weight Management|DRUG: Lupron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emotional Perceptual Training as a Treatment for Social Anxiety: Behavioral and Neural Evidence.
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Social Anxiety Disorder
Interventions: BEHAVIORAL: Perceptual Retraining|BEHAVIORAL: Gender Discrimination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic Interval Training on Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: BEHAVIORAL: Aerobic Interval training|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety of HIV and Hep C Vaccine Candidates When Given Separately or in Combination
Status: COMPLETED
Conditions: Hepatitis C Infection|HIV Infection
Interventions: BIOLOGICAL: AdCh3NSmut1|BIOLOGICAL: MVA-NSmut|BIOLOGICAL: ChAdV63.HIVconsv|BIOLOGICAL: MVA.HIVconsv
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Student Mental Health: Adaptive School-based Implementation of CBT
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Stage 1 Strategy: REP|BEHAVIORAL: Stage 1 Strategy: REP + Coaching|BEHAVIORAL: Stage 2 Strategy: Augment with Facilitation|BEHAVIORAL: Stage 2 Strategy: No augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function
Status: COMPLETED
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: K-877|DRUG: Fenofibrate|DRUG: Placebo (for K-877)|DRUG: Placebo (for Fenofibrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial Cancer
Status: TERMINATED
Conditions: Lymphedema|Stage 0 Cervical Cancer|Stage 0 Uterine Corpus Cancer|Stage 0 Vulvar Cancer|Stage I Uterine Corpus Cancer|Stage I Vulvar Cancer|Stage IA Cervical Cancer|Stage IB Cervical Cancer|Stage II Uterine Corpus Cancer|Stage II Vulvar Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage III Uterine Corpus Cancer|Stage III Vulvar Cancer|Stage IV Uterine Corpus Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer|Stage IVB Vulvar Cancer
Interventions: PROCEDURE: Management of Therapy Complications|PROCEDURE: Management of Therapy Complications|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Concordance and Acceptability of Self-screening Versus Screening by a Healthcare Professional for HPV, a Risk Factor for Anal Cancer, by Swab in People Living With HIV
Status: NOT_YET_RECRUITING
Conditions: HPV Infection
Interventions: DIAGNOSTIC_TEST: anal swabbing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Health Systems Reach Interventions Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking, Cigarette|Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: Combination nicotine patch and nicotine mini-lozenge treatment|BEHAVIORAL: Monetary incentives for initiating treatment|BEHAVIORAL: Automated tailored outreach|BEHAVIORAL: Care management|OTHER: Wisconsin Tobacco Quit Line referral|OTHER: Primary care provider referral|BEHAVIORAL: Untailored outreach|BEHAVIORAL: Multiple smoking cessation coaching calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Community-based Accompaniment With Supervised Antiretrovirals in Lima, Peru
Status: COMPLETED
Conditions: HIV|AIDS|HIV Infections
Interventions: OTHER: DOT-HAART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Investigational Allogeneic Cell Therapy Product hOMSC300 for Treatment of Early- to Moderate Stage MSA
Status: RECRUITING
Conditions: Multiple System Atrophy|MSA - Multiple System Atrophy
Interventions: DRUG: hOMSC300|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Single and Multiple Ascending Doses of Oral RO7020531 in Chinese Healthy Participants.
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: RO7020531|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ElastoMRI Evaluation of Hepatic Metastases in Colorectal Cancer ( MetaIRM)
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer With Liver Metastases
Interventions: OTHER: an elastoMRI sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy and Bevacizumab in Treating Patients With Advanced Neuroendocrine Tumors
Status: TERMINATED
Conditions: Gastrointestinal Carcinoid Tumor|Islet Cell Tumor|Lung Cancer|Neoplastic Syndrome|Neuroendocrine Tumor
Interventions: BIOLOGICAL: bevacizumab|DRUG: 5-fluorouracil|DRUG: leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Risk Factors for Multi-system Inflammatory Syndrome in Children and Pediatric Post COVID Condition
Status: RECRUITING
Conditions: COVID-19|Post-Acute COVID-19|Post-Acute COVID19 Syndrome|Multi-System Inflammatory Syndrome in Children|Pediatric Inflammatory Multisystem Syndrome|Post COVID-19 Condition|Post-COVID-19 Syndrome
Interventions: GENETIC: Saliva collection at home
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes
Status: COMPLETED
Conditions: Overweight and Obesity|Vitamin D Deficiency|Magnesium Deficiency|Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Vitamin D and magnesium|DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: MedJ-01 Ridaforolimus Eluting Coronary Stent System Trial (JNIR)
Status: COMPLETED
Conditions: de Novo or Restenosis Lesions
Interventions: DEVICE: MedJ-01 Ridaforolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Oxygen Delivery as an Early Predictor of Postoperative Pulmonary Complications During One-lung Pulmonary Ventilation in Thoracic Surgery. A Pilot Study
Status: UNKNOWN
Conditions: Postoperative Pulmonary Complications
Interventions: DIAGNOSTIC_TEST: Standard surgical monitoring, along with the Flo Trac® system monitoring.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: Imatinib|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness to Mitigate the Effect of Anxiety-depression-fear in Chronic Obstructive Pulmonary Disease (COPD)
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: WORK-ON Vocational Rehabilitation for People With Inflammatory Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Axial Spondyloarthritis
Interventions: OTHER: WORK-ON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer
Status: WITHDRAWN
Conditions: HER2-positive Breast Cancer|HER2 Low|SYD-985|SYD985|Vic-trastuzumab Duocarmazine|Metastatic Cancer|Metastatic Breast Cancer|Metastatic Gastrointestinal Carcinoid Tumor|Metastatic|HER2 Low Breast Cancer|GastroEsophageal Cancer|Gastroesophageal Adenocarcinoma|Endometrium Tumor|Ovarian Cancer|Ovarian Carcinoma|HER2-positive Gastric Cancer|HER2-positive Metastatic Breast Cancer|HER2 Mutation-Related Tumors|HER-2 Protein Overexpression|HER2 Low HR Positive|HR Positive|Hormone Receptor-positive Breast Cancer|Estrogen Receptor Positive Tumor|Progesterone Receptor-positive Breast Cancer|Triple Negative Breast Cancer|Hormone Receptor Negative Breast Carcinoma|Bladder Cancer
Interventions: DRUG: Vic-trastuzumab duocarmazine (SYD985) + paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tracheal Ultrasound With Capnography for Intubation Confirmation During CPR Wearing PPE
Status: UNKNOWN
Conditions: Cardiopulmonary Arrest
Interventions: PROCEDURE: tracheal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Care Bundle's Impact on Delirium Prevention in CABG Patients
Status: RECRUITING
Conditions: Delirium|Bypass Complication|Coronary Artery Bypass|Patient Care Bundles
Interventions: OTHER: Earplugs|OTHER: Music Therapy|OTHER: Presence of Family After Extubation:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Antipyretics for Preventing Recurrences of Febrile Seizures
Status: COMPLETED
Conditions: Recurrence of Febrile Seizure
Interventions: DRUG: Diclofenac, Paracetamol, Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
Status: COMPLETED
Conditions: Insomnia|Suicidal Ideation
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulligan and Cyriax Approach in Patients With Subacute Lateral Epicondylitis.
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Cyriax approach i.e. DTF massage and Mill's manipulation|OTHER: Mulligan approach i.e. Taping and MWM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Basal Insulins for Patients With Type 2 Diabetes Taking Oral Diabetes Medicines and Exenatide
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Lispro Protamine Suspension|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-CD7 CAR-T Cells in Pediatric and Young Adult Patients With Relapse and Refractory T-ALL/ T-LBL
Status: WITHDRAWN
Conditions: T-cell Acute Lymphoblastic Leukemia|T-lymphoblastic Lymphoma
Interventions: BIOLOGICAL: Target CD7 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalamic Deep Brain Stimulation for Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DEVICE: Bilateral Deep brain stimulation of the thalamus, Medtronic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Focal Lesion Ablative Microboost in prostatE Cancer 2.0
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Prostate Cancer|Prostate Neoplasm
Interventions: RADIATION: Hypo-FLAME 2.0 study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Repletion in Patients With Hepatocellular Carcinoma on the Orthotopic Liver Transplant List
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Hepatocellular Carcinoma
Interventions: DRUG: Vitamin D3 4000 IU|DRUG: Vitamin D3 2000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normalization of Fasting Glucose and the Incidence of Restenosis After Peripheral Angioplasty
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Peripheral Vascular Disease
Interventions: DRUG: Insulin glargine plus insulin analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
Status: COMPLETED
Conditions: Dementia, Mild|Mild Cognitive Impairment|Disability Physical|Impairment, Cognitive|Caregiver Burden|Quality of Life|Depression
Interventions: BEHAVIORAL: CAPABLE Family - Open Label Pilot|BEHAVIORAL: CAPABLE Family - Randomized Control Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate the Relative Efficacy of Terbutaline Turbuhaler® and Salbutamol Pressurized Metered Dose Inhaler (pMDI) a Single Blind Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Terbutaline Turbuhaler®|DRUG: Salbutamol pMDI|OTHER: pMDI placebo pMDI|OTHER: Placebo Turbuhaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Palladium-103 Seed Implant and Single Daily Dosing of Uroxatral Vs. Twice Daily Dosing of Flomax- A 3 Month Retrospective Efficacy Analysis
Status: COMPLETED
Conditions: Prostate Cancer Patients Undergoing External Radiation and Seed Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CF101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc and Nicotinamide Riboside for Idiopathic Pulmonary Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Zinc|OTHER: Placebos for zinc and nicotinamide riboside|DRUG: Nicotinamide riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ITA - Clinical Study Comparing ARIMIDEX™ With NOLVADEX™ in Women With Breast Cancer Treated With NOLVADEX for at Least 2 Years
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment for HPV16+ ASC-US or LSIL
Status: RECRUITING
Conditions: ASC-US|LSIL
Interventions: BIOLOGICAL: pNGVL4aCRTE6E7L2|BIOLOGICAL: TA-CIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT