pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Status: NOT_YET_RECRUITING
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: DEVICE: SIMEOX|OTHER: Remote Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Do Fish Oils Prevent Restenosis Post-Coronary Angioplasty?
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: BEHAVIORAL: dietary supplements|DRUG: fatty acids, omega-3|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Esketamine on Abdominal Pain During TACE-HAIC in Patients With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Transarterial Chemoembolization|Hepatic Arterial Infusion Chemotherapy|Pain
Interventions: DRUG: Esketamine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Optimization Trial of VXA-G1.1-NN in Healthy Volunteers
Status: COMPLETED
Conditions: Norovirus Gastroenteritis
Interventions: BIOLOGICAL: VXA-G1.1-NN Oral Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer|Adenocarcinoma
Interventions: DRUG: Pembrolizumab Monotherapy|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Metronidazole Cream in the Prevention and Treatment of Tarceva (Erlotinib)-Associated Rash
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Metronidazole Actavis|OTHER: Non-active Moisturizing Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Nab-paclitaxel Plus S-1 vs Gemcitabine Plus Cisplatin as 1-line Chemotherapy of Patients With Local Advanced and/or Metastatic Transitional Cell Carcinoma of Urothelial Tract
Status: COMPLETED
Conditions: Carcinoma, Transitional Cell
Interventions: DRUG: nanoparticle albumin-bound paclitaxel, S-1|DRUG: Gemcitabine, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis (EoE)
Interventions: DRUG: budesonide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of Multiple Doses of JS002 in Patients With Hyperlipidemia..
Status: COMPLETED
Conditions: Hyperlipemia
Interventions: BIOLOGICAL: Biological：JS002|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Xolair(Omalizumab) on Improving the Tolerability of Specific Immunotherapy in Patients With at Least Moderate Persistent Allergic Asthma Inadequately Controlled With Inhaled Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Endoscopic Dilatation With Eso-Filp in Benign Esophageal Strictures
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DEVICE: Eso-Flip
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Nivolumab|DRUG: Nanoliposomal-Irinotecan|DRUG: 5-Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Alexa as a Cognitive Aid for Emergency Front Of Neck Access (FONA)
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Use of Alexa Visual Cognitive aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a Blood Potassium Measurement Device From Capillary Samples (ALPHA)
Status: COMPLETED
Conditions: Potassium Measurement
Interventions: OTHER: Capillary blood sampling|OTHER: Venous blood sampling|OTHER: Arterio-venous blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Pharmacokinetic Study of WH-1 Ointment in Subjects With Chronic Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: WH-1 ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAS102 in Patients With ER-positive, HER2-negative Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Chemotherapy Effect
Interventions: DRUG: trifluridine/tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benzamide Derivates as Treatment of Clozapine-induced Hypersalivation
Status: COMPLETED
Conditions: Clozapine-induced Hypersalivation
Interventions: DRUG: Amisulpride, Moclobemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lignocaine Nebulization for Attenuation of Intubation Stress Response
Status: UNKNOWN
Conditions: Pressor Response
Interventions: DRUG: Lignocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: GM-CSF + Naxitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Effect of Improving Sleep Quality on Cognitive Function in Patients With Epilepsy
Status: UNKNOWN
Conditions: Epilepsy，Cognition
Interventions: OTHER: Melatonin Tablets|OTHER: Lactasin Tablets|DEVICE: transcutaneous vagus nerve stimulation|DEVICE: sham transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Raptiva in Subjects With Chronic Moderate or Worse Plaque Psoriasis Who Have Had an Inadequate Response to an Anti-TNF Agent
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: efalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: Fludarabine|DRUG: Cyclophosphamide|PROCEDURE: CD3±CD19 depleted hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Postoperative Pain After Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis of Hip
Interventions: DRUG: Bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Adding Bevacizumab Therapy in Glaucoma Surgery Improve the Success of Needle Bleb Revisions?
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: bevacizumab|OTHER: balanced salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Efficacy and Pharmacodynamics of CAL02 in Severe Pneumonia Caused by Streptococcus Pneumoniae
Status: COMPLETED
Conditions: Pneumonia|Pneumococcal Infections
Interventions: DRUG: CAL02 Low-dose|DRUG: CAL02 High-dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Stent Occlusion
Interventions: OTHER: Prolonged inflation|OTHER: Rapid inflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Human Safety and Dose-Finding Study of New Type-16 Human Rhinovirus (RG-HRV16) Inoculum in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: RG-HRV16|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: BIIB122|DRUG: BIIB122-Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have Not Previously Taken Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo to Upadacitinib|DRUG: Methotrexate|DRUG: Placebo to Methotrexate|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Production of Reactive Oxygen Species in Response to Glutathione Supplementation and Acute Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes|Oxidative Stress|Mitochondrial Reactive Oxygen Species Production
Interventions: DIETARY_SUPPLEMENT: Glutathione|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility, Female
Interventions: DRUG: Long GnRH agonist + HRT|DRUG: HRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia|Metabolic Syndrome
Interventions: DRUG: ezetimibe (+) simvastatin|DRUG: Comparator: atorvastatin calcium|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ERX1000 - Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Male and Female Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: ERX1000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Automated Closed-loop Ventilator vs Conventional Open-loop Ventilator in the Emergency Department
Status: NOT_YET_RECRUITING
Conditions: Ventilator Lung|Mechanical Ventilation Complication|Ventilator-Induced Lung Injury|ARDS
Interventions: DEVICE: Closed-loop ventilator|DEVICE: Open-loop ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics, Safety and Tolerability of BI 671800 HEA Given Over 7 Days. A Randomised, Double Blind, Placebo Controlled Within Dose Groups Phase I Study in Healthy Male and Female Volunteers.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: BI 671800|DRUG: BI 671800
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cervical Intraepithelial Neoplasia (CIN) Grade III With Non-invasive Physical Plasma
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia III
Interventions: PROCEDURE: Non-invasive physical plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Aprepitant For Prevention of Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Referral to Alcohol Use Dependency Treatment in Patients With Alcohol-related Liver Disease: a RCT
Status: RECRUITING
Conditions: Liver Diseases, Alcoholic|Alcohol Use Disorder|Treatment Adherence
Interventions: BEHAVIORAL: Offer of referral to specialized alcohol use disorder treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Papillary Extended Connective Tissue Graft in Miller Class III Gingival Recession
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: peCTG+CAF|PROCEDURE: CTG+CAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brief Behavioral Intervention to Treat ADHD and Disruptive Behaviors In Preschoolers
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Immediate Treatment Group|BEHAVIORAL: Delayed Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication
Status: COMPLETED
Conditions: Coronary Artery Disease|Carotid Artery Diseases|Atherosclerosis
Interventions: DRUG: Atorvastatin|DRUG: Niacin|DRUG: Colesevelam|DRUG: Placebo Niacin|DRUG: Placebo Colesevelam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Paracetamol Metabolism Research in Postoperative Hepatic Surgery
Status: UNKNOWN
Conditions: Paracetamol Causing Adverse Effects in Therapeutic Use|Hepatic Disease
Interventions: DRUG: paracetamol|PROCEDURE: hepatic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Left Ventricular Reshaping to Reduce Functional Mitral Regurgitation and Improve LV Function
Status: COMPLETED
Conditions: Functional Mitral Regurgitation
Interventions: DEVICE: AccuCinch® Ventriculoplasty System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balancing Risk: Red Blood Cell Transfusion Strategies In Cardiac Surgery
Status: COMPLETED
Conditions: Anemia
Interventions: PROCEDURE: Blood transfusion at hematocrit value less than 24%|PROCEDURE: Blood transfusion at hematocrit value less than 28%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Percutaneous Liver Biopsy With Needle Tract Plugging on Outpatient Basis
Status: RECRUITING
Conditions: Image-guided Biopsy|Liver Biopsy
Interventions: PROCEDURE: Conventional method|PROCEDURE: Coaxial method with needle-track plugging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Safety of AB680 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AB680|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Leukocyte-rich and Leukocyte-poor PRP for Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DRUG: Leukocyte-rich platelet-rich plasma|DRUG: Leukocyte-poor platelet-rich plasma|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Eating Disorders Prevention Interventions in At-Risk Female Students With Body Dissatisfaction
Status: COMPLETED
Conditions: Body Dissatisfaction
Interventions: BEHAVIORAL: Body Project (BP)|BEHAVIORAL: Healthy Weight Program (HW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Restriction of the Non Paretic Upper Limb Rehabilitation of Patients a With Stroke:Randomized Clinical Trial
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: specific training of paretic upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Albumin Versus Standard Dose Albumin in High Risk Spontaneous Bacterial Peritonitis.
Status: COMPLETED
Conditions: Spontaneous Bacterial Peritonitis
Interventions: BIOLOGICAL: Low Dose Albumin|BIOLOGICAL: Standard dose Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Liver Metastases
Interventions: DRUG: oxaliplatin, capecitabine, trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps Only
Status: COMPLETED
Conditions: Aspirin-exacerbated Respiratory Disease|Nasal Polyp
Interventions: GENETIC: microRNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Response Study of Lasofoxifene in Postmenopausal Women With Osteoporosis - Japanese Asian Dose Evaluation
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: lasofoxifene|DRUG: Placebo|DRUG: Lasofoxifene|DRUG: Lasofoxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial Infarction
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction|Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: Methoxyflurane - Penthrox|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Visualization of Uncertainty in Clinical Diagnostic Reasoning for Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism|Diagnostic Uncertainty|Clinical Reasoning|Evidence Based Medicine|Visualization of Uncertainty
Interventions: OTHER: Visualized pulmonary embolism computer task model|OTHER: Didactic review lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Assess the Safety, Tolerability and PK Profile of FDL176 in Healthy and CF Participants
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: FDL176|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Levels in Umbilical Cord and It's Impact on Infant and Children's Health (VITADi Study)
Status: UNKNOWN
Conditions: Vitamin D Deficiency
Interventions: OTHER: Anthropometric measurement for pregnant women|OTHER: Anthropometric measurement for infants|OTHER: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Low-Dose Intravenous Decitabine in Patients Aged > 60 Years With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine 15 mg/m2 i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Erythromycin in GER-Associated Apnea of the Newborn
Status: UNKNOWN
Conditions: Gastroesophageal Reflux|Apnea|Bradycardia
Interventions: DRUG: Erythromycin|DEVICE: Multi-channel intra-luminal impedance (MII) pH monitoring|DRUG: Placebo (D5W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nanoparticulate Versus Micronized Steroids Delivery for Transdermal Hormone Replacement Therapy
Status: COMPLETED
Conditions: Menopausal Syndrome
Interventions: DRUG: Micronized estradiol + progesterone|DRUG: Nanoparticulate estradiol + progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Specific Tumor Target Drug Plus Immune System Therapy in Patients With Kidney Cancer
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Bevacizumab|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Association of Nonalcoholic Fatty Liver Disease With Colorectal Malignant Neoplasm
Status: COMPLETED
Conditions: Colorectal Neoplasms|Nonalcoholic Fatty Liver Disease
Interventions: OTHER: Ultrasound examination and Colonoscopy examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COVID-19 Positive Outpatient Thrombosis Prevention in Adults Aged 40-80
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Apixaban 2.5 MG|DRUG: Apixaban 5MG|DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Lower Pneumoperitoneum Pressure During Laparoscopic and Robotic Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy|Pneumoperitoneum
Interventions: OTHER: Pneumoperitoneum pressure = 15mmHg|OTHER: Pneumoperitoneum pressure = 12mm Hg|OTHER: Pneumoperitoneum pressure = 10mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adolescent Weight Management Study
Status: COMPLETED
Conditions: Protocol #1:Behavioral Therapy + Placebo or Sibutramine|Protocol #2: Behavioral Therapy + Meal Replacement or Conventional Food
Interventions: DRUG: Sibutramine|DIETARY_SUPPLEMENT: Slim Fast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the Specificity of the Cobas TaqScreen MPX Test for Use on the Cobas s 201 System for Screening Plasma Pools From Source Plasma Donors for the Presence of HBV DNA, HCV RNA, and HIV-1 RNA
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DEVICE: cobas s 201 TaqScreen MPX Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Gingival Recessions
Status: RECRUITING
Conditions: Gingival Recession Generalized Moderate
Interventions: PROCEDURE: Coronally advanced flap and deepithelized free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: DRUG: Cathflo Activase|DRUG: Talc Slurry Pleurodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sort Out XI - Combo Stent Versus BioMatrix Alpha Stent
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: COMBINATION_PRODUCT: PCI with BioMatrix Alpha™ stent|COMBINATION_PRODUCT: PCI with Combo™ stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Integrated Optimization Schemes for Female Stress Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence in Women
Interventions: DEVICE: Electroacupuncture group|DEVICE: Sham electroacupuncture group|BEHAVIORAL: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors
Status: RECRUITING
Conditions: MTAP-null Non-Small-Cell Lung Cancer|MTAP-null Solid Tumors
Interventions: DRUG: AMG 193|DRUG: IDE397
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Etrasimod|DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PT001 MDI Versus Spiriva® in Patients With Moderate to Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT001 MDI|DRUG: Tiotropium Bromide|DRUG: PT001 Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Imaging of Glutamate Carboxypeptidase II With DCFPyL-PET
Status: COMPLETED
Conditions: Schwannomas|Malignant Tumors
Interventions: DRUG: 18F-DCFPyL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Music Therapy on Glutathione Peroxidase, Malondialdehyde and Pain in Oocyt Pick Up Patients.
Status: COMPLETED
Conditions: Infertility|Anesthesia|Oxidative Stress|Pain, Postoperative
Interventions: OTHER: music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Photobiomodulation on the Treatment of Soft Tissue Traumatic Injuries
Status: UNKNOWN
Conditions: Soft Tissue Injuries
Interventions: RADIATION: Photobiomodulation|OTHER: Sham Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Added Value of Contrast-enhanced Ultrasonography for Percutaneous Radiofrequency Ablation
Status: COMPLETED
Conditions: Radiofrequency Ablation|Ultrasonography|Liver Tumors
Interventions: PROCEDURE: Percutaneous Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Erector Spinae Plane and Caudal Block on Postoperative Stress Response
Status: COMPLETED
Conditions: Post Operative Pain|Stress Response|Erector Spinae Plane Block|Caudal Block
Interventions: PROCEDURE: Ultrasound-guided erector spinae plan block|PROCEDURE: Ultrasound-guided caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Sports-inspired Onco-coaching on Health-related Quality's Life of the Patients in Cancer Remission After Allogeneic Transplantation of Hematopoietic Stem Cells
Status: NOT_YET_RECRUITING
Conditions: Hematological Cancer
Interventions: OTHER: interviews with coachs, semi-structured interviews and questionnaires|OTHER: semi-structured interviews and questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical Calcipotriene Treatment for Breast Cancer Immunoprevention
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Topical Calcipotriene Ointment|OTHER: Topical Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of EVP-0962 and Effects of EVP-0962 on Cerebral Spinal Fluid Amyloid Concentrations in Healthy Subjects and in Subjects With Mild Cognitive Impairment or Early Alzheimer's Disease
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DRUG: EVP-0962|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No Symptoms
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate ASN002 Absorption, Metabolism, and Excretion of [14C] Following a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: [14C] ASN002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects
Status: WITHDRAWN
Conditions: Tuberculosis|Hiv
Interventions: DRUG: Rifapentine daily|DRUG: Rifapentine weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
Status: COMPLETED
Conditions: Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing IUI
Interventions: DRUG: HCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Different Body Positions During Facemask Ventilation in Obese Patients
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: OTHER: Head position for face mask ventilation during induction supine|OTHER: Head position for face mask ventilation during induction head elevated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Treatment Response With CHOI and RECIST Criteria and CT Texture Analysis in Patients With Metastatic Colorectal Cancer Treated With Regorafenib
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Glycemic Index on Sleep and Memory Consolidation
Status: COMPLETED
Conditions: Sleep Architecture|Cognitive Function|Mood|Glucose Metabolism
Interventions: DIETARY_SUPPLEMENT: Low glycemic index drink|DIETARY_SUPPLEMENT: High glycemic index drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: COMS for Chronic Ulcers Treatment
Status: NOT_YET_RECRUITING
Conditions: Venous Leg Ulcer|Wound Heal|Magnetic Field Exposure
Interventions: COMBINATION_PRODUCT: Concurrent optical and magnetic stimulation (COMS) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Confirmatory Study Nepafenac 0.3%
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Nepafenac Ophthalmic Suspension, 0.3%|DRUG: Nepafenac Ophthalmic Suspension, 0.1%|OTHER: Nepafenac Ophthalmic Suspension 0.3% Vehicle|OTHER: NEVANAC Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Bevacizumab and Irinotecan for Patients With Malignant Glioblastomas
Status: COMPLETED
Conditions: Malignant Gliomas
Interventions: DRUG: Cetuximab|DRUG: Bevacizumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study for the Risky Decision-making Deficits Among Methamphetamine Dependence Individuals and Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Methamphetamine Use Disorder
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VB10.NEO in Combination With Atezolizumab in Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors, Adult
Interventions: BIOLOGICAL: VB10.NEO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: root canal treatment, anesthesia, pain medications, and antibiotic|PROCEDURE: no root canal treatment, anesthesia, pain medications, and antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Goff Transpancreatic Septotomy vs. Double Wire Technique for Achieving Biliary Access in Technically Challenging ERCPs
Status: COMPLETED
Conditions: Biliary Obstruction|Biliary Stones
Interventions: PROCEDURE: Goff trans-pancreatic septotomy vs. Double wire technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leeches for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Arthralgia
Interventions: PROCEDURE: Single Leeching|PROCEDURE: Repeated Leeching after 4 weeks|PROCEDURE: Placebo Leeching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Folate in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 5-MTHF glucosamine salt|DIETARY_SUPPLEMENT: 5-MTHF calcium salt 1|DIETARY_SUPPLEMENT: 5-MTHF calcium salt 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a PCM Mattress to Treat HIE Infants During Transport
Status: ACTIVE_NOT_RECRUITING
Conditions: Newborn Hypoxic-Ischemic Encephalopathy
Interventions: DEVICE: The NeoHilda Point of care method|PROCEDURE: Traditional evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Quality of Life After Discharge of the Mild and Moderate COVID-19 Patients With or Without Herbal Medicine
Status: COMPLETED
Conditions: COVID-19 Pandemic|Quality of Life
Interventions: DRUG: Shen Cao Gan Jiang Tang (Gan Cao Gan Jiang Tang with Ginseng)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is Masseteric Nerve Block Effective in Myofascial Pain
Status: COMPLETED
Conditions: Myofascial Pain - Dysfunction Syndrome of TMJ|Myofascial Trigger Point Pain|Local Anesthesia
Interventions: PROCEDURE: masseteric nerve block|PROCEDURE: trigger point injection|PROCEDURE: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
Status: TERMINATED
Conditions: Bone Marrow Suppression|Brain and Central Nervous System Tumors|Drug/Agent Toxicity by Tissue/Organ|Long-term Effects Secondary to Cancer Therapy in Children
Interventions: BIOLOGICAL: filgrastim|DRUG: acetylcysteine|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide phosphate|DRUG: mannitol|DRUG: sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Olive Oil for Reducing Facial Pain of Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DIETARY_SUPPLEMENT: Olive oil and Dietary Guideline recommendations|OTHER: Dietary Guideline recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lenalidomide as Initial Treatment of Patients With Chronic Lymphocytic Leukemia (CLL) Age 65 and Older
Status: COMPLETED
Conditions: Leukemia|CLL|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Philippine Trial to Determine Efficacy and Safety of Favipiravir for COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Favipiravir + Standard of Care|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Palbociclib and Dexamethasone in Treating Participants With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Recurrent B Acute Lymphoblastic Leukemia|Refractory B Acute Lymphoblastic Leukemia
Interventions: DRUG: Palbociclib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Abuse Potential of Hydrocodone Extended-Release Tablet in Recreational Opioid Users
Status: COMPLETED
Conditions: Drug Abuse
Interventions: DRUG: 45-mg hydrocodone bitartrate extended-release tablet (crushed or intact)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EpiDetect Study: Clinical Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Patients
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DEVICE: Early detection pancreatic cancer test|DEVICE: Early detection pancreatic cancer test and MRI Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase 1 Study to Evaluate the Safety and Immunogenicity of a Candidate Vaccine Against Respiratory Syncytial Virus
Status: COMPLETED
Conditions: Acute Bronchiolitis Due to Respiratory Syncytial Virus
Interventions: BIOLOGICAL: V-306 candidate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Adding Photobiomodulation to a Specific Therapeutic Exercise Program for the Treatment of Individuals With Chronic Nonspecific Neck Pain.
Status: RECRUITING
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Therapeutic exercise|OTHER: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Pharmacokinetic Similarity of MB09 and EU/US-Sourced Xgeva
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MB09 (denosumab biosimilar)|DRUG: US-sourced Xgeva|DRUG: EU-sourced Xgeva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 706321 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 706321|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical Botulinum Toxin A Injections in Treatment of Interstitial Cystitis Refractory to Conventional Treatment
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: Botulinum toxin A|DRUG: Normal saline instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Compare Efficacy and Safety of DHP107 vs. Taxol® in Patients With Metastatic or Recurrent Gastric Cancer
Status: COMPLETED
Conditions: Stage IV Gastric Cancer
Interventions: DRUG: Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare How Tamsulosin is Absorbed to the Body After Administration of Two Types of Tamsulosin Formulation Under Fed and Fasted Conditions in Chinese Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Tamsulosin Hydrochloride
Interventions: DRUG: Tamsulosin formulation-A|DRUG: Tamsulosin formulation-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: