pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study
Status: RECRUITING
Conditions: Sleep Apnea|Breathing Disorder During Sleeping|Sleep Disorder|Spinal Cord Injuries|Spine Disease
Interventions: DEVICE: CPAP Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Traumeel® / Zeel® Injectable Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health-Related Quality of Life and Disease-Related Costs: Comparison Between Ankylosing Spondylitis, Rheumatoid Arthritis and Systemic Lupus Erythematosus in Taiwan
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Systemic Lupus Erythematosus|Ankylosing Spondylitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Performance and Safety of T2769 Versus Vismed® Multi in the Treatment of Moderate to Severe Dry Eye Syndrome
Status: RECRUITING
Conditions: Dry Eye
Interventions: DEVICE: T2769|DEVICE: Vismed® Multi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pneumoperitoneum on the Continuous and Non-invasive Hemoglobin Monitoring
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: OTHER: High end-tidal CO2|OTHER: Low CO2 group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multivitamin Dosage Regimens in the Prevention of Adverse Pregnancy Outcomes Among HIV-Positive Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DIETARY_SUPPLEMENT: Multivitamins-Multiples of RDA|DIETARY_SUPPLEMENT: Multivitamins-Single RDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgical Italian Guide for the Management of Complicated Acute Diverticulitis Emergency Setting (SIGMA-D). A Prospective Observational Multicenter Study on Behalf of the Italian Society of Colorectal Surgery (SICCR).
Status: RECRUITING
Conditions: Acute Diverticulitis|Stoma Colostomy|Stoma Ileostomy
Interventions: PROCEDURE: sigmoid resection and anastomosis / stoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin as Adjuvant Therapy in Breast Cancer Patients
Status: UNKNOWN
Conditions: Stage II and III Breast Cancer
Interventions: DRUG: Melatonin|DRUG: match placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Postoperative Renal Function Recovery After Kidney Transplantation in Adult Patients
Status: UNKNOWN
Conditions: Renal Failure
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9%NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Role of EUS Guided FNA of Portal Vein Thrombus in the Diagnosis and Staging of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Portal Vein Thrombosis
Interventions: PROCEDURE: EUS guided fine needle aspiration of portal vein thrombus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Types of Braces in the Treatment of Rockwood Type III AC-dislocations
Status: COMPLETED
Conditions: Acromioclavicular Joint Dislocation
Interventions: DEVICE: Acromion 2.0 Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Trial of CVL-936 in Healthy Subjects
Status: TERMINATED
Conditions: Substance Use Disorders (SUD)
Interventions: DRUG: CVL-936|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Bevacizumab|DRUG: Pemetrexed|OTHER: Best Supportive Care|DRUG: nab-Paclitaxel|DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Erlotinib|DRUG: Crizotinib|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Minimum Effective Concentration of Lidocaine for Ultrasound-guided Axillary Block for Arterio-venous Fistula Creation Surgery
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Lidocaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Single Ascending Doses of PUL-042 Inhalation Solution in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PUL-042 Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sensory Neuromodulation Protocol for the Treatment of Post-stroke Oropharyngeal Dysphagia.
Status: COMPLETED
Conditions: Swallowing Disorder|Dysphagia|Stroke|Neurophysiologic Abnormality
Interventions: DEVICE: rTMS active and sham|DEVICE: PES active and sham|DIETARY_SUPPLEMENT: Capsaicin active and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Misoprostol in Office Hysteroscopy and Endometrial Biopsy
Status: WITHDRAWN
Conditions: Office Hysteroscopy and Endometrial Biopsy
Interventions: DRUG: Misoprostol 50 mcg pesssary|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiotherapy With or Without Darolutamide for OligoRecurrent Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Cancer Recurrent|Prostate Cancer Metastatic|Metastatic Cancer|Oligometastasis
Interventions: DRUG: Darolutamide|RADIATION: metastasis-directed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids.
Status: COMPLETED
Conditions: Symptomatic Uterine Leiomyomas|Fibroids|Uterine Fibroids|Myomas
Interventions: PROCEDURE: Focused ultrasound (MRgFUS)|PROCEDURE: Uterine artery embolization (UAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Percutaneous Laparoscopic Assisted Internal Ring Ligation During Lap Orchiopexy
Status: UNKNOWN
Conditions: Congenital Disorders
Interventions: PROCEDURE: new laparoscopic orchiopexy|PROCEDURE: classic laparoscopic orchiopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBD Neoplasia Surveillance Pilot RCT
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Colonic Neoplasms|Dysplasia
Interventions: DIAGNOSTIC_TEST: Intervention Group|DIAGNOSTIC_TEST: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril
Status: UNKNOWN
Conditions: Heart Failure|Dilated Cardiomyopathy|Congenital Heart Disease
Interventions: DRUG: Enalapril Orodispersible Minitablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-frequency Pulsed Electromagnetic Fields (ELF-MF) as Treatment for Acute Ischemic Stroke
Status: TERMINATED
Conditions: Stroke, Acute|Ischemic Stroke
Interventions: DEVICE: REAL Pulsed ELF-MF stimulation|DEVICE: SHAM Pulsed ELF-MF stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of ICI176,334-1 in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ICI176,334-1|DRUG: Casodex 80 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GEM/Cisplatin/S-1 vs GEM/Cisplatin for Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Gemcitabine/Cisplatin|DRUG: Gemcitabine/Cisplatin /S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Medial-to-Lateral Approach vs Dorsal and Medial Hybrid Approach in Laparoscopic Right Hemicolectomy
Status: UNKNOWN
Conditions: Overall Survival|Postoperative Complications
Interventions: PROCEDURE: DML group|PROCEDURE: MLA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35
Status: COMPLETED
Conditions: Obesity|Obstructive Sleep Apnea
Interventions: DEVICE: ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Donors Predisposed by Corneal Collagen Cross-linking in Deep Lamellar Keratoplasty for the Patients With Keratoconus
Status: NOT_YET_RECRUITING
Conditions: Keratoconus
Interventions: PROCEDURE: Corneal donors predisposed by CXL|PROCEDURE: Corneal donors stored in corneal storage media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Special Oral Nutritional Supplement on Nutritional Status of Malnourished Elderly Patients
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutri-Energie ®, Aliscience society|DIETARY_SUPPLEMENT: Clinutren 1.5 ®, Nestlé Clinical Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: RAD001|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinblastine for Leukoreduction in Newly Diagnosed AML and Hyperleukocytosis
Status: RECRUITING
Conditions: AML|Hyperleukocytosis
Interventions: DRUG: Vinblastine|DRUG: Hydroxyurea capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Analgesic Effect of Oral Nefopam
Status: RECRUITING
Conditions: Postoperative Pain After a Total Knee Arthroplasty
Interventions: DRUG: Oral nefopam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen's Antinociceptive Effect When Associated With N-Acetylcysteneine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: N-acetylcysteine combination with acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: Vincristine Sulfate Liposome|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep & Quality of Life Evaluation of Patients With Atopic Dermatitis Based on E-diary on a Smartphone Application and Actigraphy
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: OTHER: electronic-Patient Report Outcome and wear of a wristband actigraph
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia.
Status: UNKNOWN
Conditions: Bidirectional Endoscopy|Deep Sedation
Interventions: PROCEDURE: EGD first|PROCEDURE: Colonoscopy first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Oblimersen and Imatinib Mesylate in Treating Patients With Advanced Gastrointestinal Stromal Tumors That Cannot Be Removed By Surgery
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Counseling for Prenatal Screening and Diagnostic Tests on Pregnant Women: Randomised Controlled Study
Status: COMPLETED
Conditions: Decision Making|Chromosome Abnormality|Anxiety|Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Prenatal Genetic Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of PICO Single-use System in Chronic Ulcers
Status: NOT_YET_RECRUITING
Conditions: Chronic Ulcer|Venous Ulcer|Diabetic Foot Ulcer|Pressure Injury
Interventions: DEVICE: Single-use negative pressure therapy (PICO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intercostal Nerve Block With Dexamethasone and Ropivacaine on Rebound Pain After Thoracoscopic Surgery
Status: NOT_YET_RECRUITING
Conditions: Rebound Pain|Dexamethasone|Intercostal Nerve Block|Thoracoscopic Surgery
Interventions: DRUG: Dexamethasone 8mg+0.375% ropivacaine|DRUG: 0.375% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD22 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy for Relapsed Refractory B-cell Malignancies
Status: UNKNOWN
Conditions: B Cell Lymphoma|Acute Lymphoblastic Leukemia
Interventions: GENETIC: Third generation CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: HDV-Lispro|DRUG: Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant for Bone Marrow Failure Syndromes
Status: COMPLETED
Conditions: Diamond-Blackfan Anemia|Kostmann's Neutropenia|Shwachman-Diamond Syndrome
Interventions: PROCEDURE: Stem cell transplant|DRUG: Fludarabine monophosphate|PROCEDURE: Total lymphoid irradiation|DRUG: Busulfan|BIOLOGICAL: anti-thymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cold Application and Vibration in Reducing Pain During Vaccination in Children
Status: RECRUITING
Conditions: Pain|Pain, Acute|Vaccination|Children|Cold Application|Vibration
Interventions: DEVICE: Buzzy|DEVICE: Buzzy (Placed in standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alzer® and Diamel® to Prevent Severe Diabetes Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DIETARY_SUPPLEMENT: Oral treatment Alzer y Diamel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate ActiMyo Measured Activity in Parkinson Disease Patients & Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson Disease|Healthy Volunteers
Interventions: DRUG: Levodopa acute challenge|OTHER: Controlled environment tests (series of tasks of everyday life)|OTHER: Standardized scales: MDS-UPDRS (Part II to IV) and RDRS|DEVICE: ActiMyo recording|OTHER: Diary completion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Advance Care Planning Programme for Persons With Early Stage Dementia in the Community
Status: COMPLETED
Conditions: Dementia Mild|Mild Cognitive Impairment
Interventions: BEHAVIORAL: ACP programme "Have a Say"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nocturnal Oxygen Treatment in Heart Failure and Cheyne-Stokes Respiration
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: nocturnal oxygen treatment from oxygen concentrators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shockwave Therapy in Lower Limb Intermittent Calf Claudication
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Vacc-C5 With Adjuvant GM-CSF or Alhydrogel in HIV-1-infected Subjects on ART
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Vacc-C5/GM-CSF|DRUG: Vacc-C5/Alhydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Once a Day Dose Compared to 2 Doses/Day
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Mesalamine Once-Daily|DRUG: Mesalamine Twice-Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Arikayce™ in CF Patients With Chronic Pseudomonas Aeruginosa Infections
Status: COMPLETED
Conditions: Pseudomonas Aeruginosa Infection
Interventions: DRUG: Liposomal amikacin for inhalation (Arikayce™) using the PARI Investigational eFlow® Nebulizer.|DRUG: Tobramycin inhalation solution using a PARI LC® Plus nebulizer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiotoxicities in Patients Receiving BTKi
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DIAGNOSTIC_TEST: Electrocardiogram|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: Cardiac magnetic resonance imaging|DEVICE: Mobile cardiac telemetry|DIAGNOSTIC_TEST: Blood pressure monitoring|DIAGNOSTIC_TEST: Blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of OncoSil™ Given to Patients With Pancreatic Cancer Treated With FOLFIRINOX or Gemcitabine+Abraxane
Status: COMPLETED
Conditions: Unresectable Locally Advanced Pancreatic Carcinoma
Interventions: DEVICE: OncoSil™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saudi Outcomes of ECMO-treated MERS-CoV Patients
Status: COMPLETED
Conditions: MERS-CoV Infection|Refractory Hypoxemia
Interventions: OTHER: Extracorporeal Membrane Oxygenation|OTHER: Non Extracorporeal Membrane Oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Erector Spinae Block in Kyphoplasty
Status: COMPLETED
Conditions: Spinal Fractures|Anesthesia, Regional|Anesthetics, Local|Analgesia
Interventions: PROCEDURE: CLIA Group (conventional local anesthesia infiltration)|PROCEDURE: EPIAA Group (Extrapedicular infiltration anesthesia)|PROCEDURE: ESP Group (Erector Spina Block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies
Status: COMPLETED
Conditions: Influenza|Common Cold
Interventions: DRUG: Paracetamol|DRUG: Phenylephrine|DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis
Status: RECRUITING
Conditions: Septic Shock
Interventions: DEVICE: Low Level Transcutaneous Vagus Nerve Stimulation|DEVICE: Low Level Transcutaneous Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Link Between Sleep and Brain Clearance
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Aging
Interventions: BEHAVIORAL: Auditory Stimulation|BEHAVIORAL: Sham (no stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia
Status: COMPLETED
Conditions: Multiple System Atrophy, Cerebellar Variant (Disorder)|Spinocerebellar Ataxias
Interventions: DEVICE: Cerebellar repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shanghai Eye Study for Adults
Status: RECRUITING
Conditions: Blindness,Visual Impairment, Refractive Error, Cataract, High Myopia, Aging
Interventions: DEVICE: spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: AUTOANTIBODIES AND SYSTEMIC SCLEROSIS
Status: NOT_YET_RECRUITING
Conditions: Understand Pathogenicity of SSc-specific Antibodies in SSc and the Effect of Antibody Blockade in Vitro
Interventions: BIOLOGICAL: Fcr blocker of autoantibodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Caffeinated and Non-caffeinated Pre-workout Supplements on Resistance Exercise Performance
Status: COMPLETED
Conditions: Resistance Training|Caffeine|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Caffeinated pre-workout supplement|DIETARY_SUPPLEMENT: Non-caffeinated pre-workout supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of HCCD Supplemented With Omega-3 Fatty-Acids on Inflammation in Healthy, Overweight Subjects
Status: UNKNOWN
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acids|OTHER: high complex carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Primary Plasma Cell Leukemia: a Prospective Phase 2 Study Incorporating Daratumumab to Chemotherapy and Stem Cell Transplantation
Status: NOT_YET_RECRUITING
Conditions: Plasma Cell Leukemia
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Of Whole Body Vibration on Planter /Dorsi Flexor Ratio, Pain and Functional Activities in Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: whole body vibration|OTHER: traditional exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Status: RECRUITING
Conditions: Preterm Premature Rupture of Membrane|Pregnancy, High Risk|Preterm Birth
Interventions: DRUG: Ceftriaxone 1000 MG|DRUG: Clarithromycin 500mg|DRUG: Metronidazole 500 mg|DRUG: Ampicillin 2 GM Injection|DRUG: Amoxicillin 250 MG|DRUG: Azithromycin|DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib or Nilotinib With Pegylated Interferon-α2b in Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: PEG-IFN-a2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Intravenous (IV) Cyclophosphamide Versus Monthly IV Cyclophosphamide
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: High-dose immunoablative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Immunoglobulin E-mediated Food Allergies in Children
Status: RECRUITING
Conditions: Non IgE Mediated Food Allergy|Food Protein-Induced Enteropathy|Food Protein-Induced Proctocolitis|Food Protein-Induced Enterocolitis Syndrome|Food Protein-induced Motility Disorders
Interventions: OTHER: Non IgE-mediated food allergy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions
Status: NOT_YET_RECRUITING
Conditions: Esophageal Neoplasm|Esophageal Polyp|Endoscopic Submucosal Dissection|Bipolar Electrocautery
Interventions: DEVICE: Speedboat™ Ultraslim
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Metastatic Renal Cell Cancer|Recurrent Bladder Carcinoma|Recurrent Classical Hodgkin Lymphoma|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Renal Cell Carcinoma|Stage III Bladder Cancer|Stage III Lymphoma|Stage III Non-Small Cell Lung Cancer AJCC v7|Stage III Renal Cell Cancer|Stage III Skin Melanoma|Stage IIIA Non-Small Cell Lung Cancer AJCC v7|Stage IIIA Skin Melanoma|Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Bladder Cancer|Stage IV Lymphoma|Stage IV Non-Small Cell Lung Cancer AJCC v7|Stage IV Renal Cell Cancer|Stage IV Skin Melanoma|Stage IVA Bladder Cancer|Stage IVB Bladder Cancer|Unresectable Head and Neck Squamous Cell Carcinoma|Unresectable Solid Neoplasm
Interventions: DRUG: Enzyme Inhibitor Therapy|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaria in Pregnancy: Nutrition and Immunologic Effects
Status: COMPLETED
Conditions: Malaria|Low Birth Weight|Anemia|Perinatal Mortality
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Zinc|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Physiotherapy Program for Diabetic Individuals on Dexterity, Proprioception, and Functionality
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: OTHER: Exercise|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Nicotine Delivery From Selected Oral Nicotine Products
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: Product A|OTHER: Product B|OTHER: Product C|OTHER: Product D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Radial Shock Waves Treatment on Spasticity in Patients With Stroke in Sub-acute Phase
Status: TERMINATED
Conditions: Spasticity, Muscle|Extracorporeal Shockwave Therapy|Rehabilitation
Interventions: PROCEDURE: Radial Extracorporeal Shock Wave Therapy|PROCEDURE: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of 3D Printed Biodegradable Cervical Interbody Fusion Cage
Status: UNKNOWN
Conditions: Symptomatic Cervical Disc Disease
Interventions: DEVICE: 3D printed biodegradable cervical fusion cage|DEVICE: PEEK cage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Informed Changes in Care for Non-Communicating Patients
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Intellectual Disability|Communication, Nonverbal
Interventions: BEHAVIORAL: HR-informed change in routine|BEHAVIORAL: Delayed HR-informed specific change in routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selenious Yeast in CLL Patients w/o Indication of Chemotherapy
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia Stage A(0)|Chronic Lymphocytic Leukemia Stage A(I)|Chronic Lymphocytic Leukemia Stage A(II)|Chronic Lymphocytic Leukaemia Stage B(I)
Interventions: DRUG: Low Dose Selenious Yeast Tablets|DRUG: High Dose Selenious Yeast Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing the Efficacy of Mulberry Twig Alkaloid Tablet and Canagliflozin in Patients With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Mulberry Twig Alkaloid Tablet|DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|DCIS|LCIS
Interventions: RADIATION: MRIdian Radiation Treatment Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease
Status: COMPLETED
Conditions: Cardiac Toxicity|Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Application of 68GA-labeled CD73 Targeting Probe PET/CT Imaging in the Diagnosis of Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: 68GA-DOTA-dPNE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stereotactic Body Radiotherapy (SBRT) and Sorafenib in Patients With Metastatic, Recurrent, or Unresectable Renal Cell Cancer (RCC)
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic body radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT-guided Lung Biopsy Risk Optimization Method
Status: NOT_YET_RECRUITING
Conditions: Pneumothorax|Biopsy, Needle|Risk Factors|Radiology, Interventional
Interventions: PROCEDURE: Fluid application during ct-guided lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib and Bevacizumab in Combination With Paclitaxel in Patients With Solid Tumors
Status: COMPLETED
Conditions: SOLID TUMORS
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Two Nasal Sprays to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: 0.15% azelastine hydrochloride 1644 mcg daily|DRUG: 0.1% azelastine hydrochloride 1096 mcg daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scrutinizing and Promoting Mindfulness Via New Technologies
Status: UNKNOWN
Conditions: Mindfulness|Stress|Mood|Working Memory
Interventions: BEHAVIORAL: Mindfulness|OTHER: Contingent RT-fMRI-NF|OTHER: Sham RT-fMRI-NF|BEHAVIORAL: Mind Wandering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Probiotics in Bangladeshi Infants
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938|DIETARY_SUPPLEMENT: Bifidobacterium longum infantis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Creatine Kinase Levels and Clinical and Functional Parameters in Parajiu-jitsu Athletes
Status: UNKNOWN
Conditions: Healthy|Deficiency Diseases
Interventions: OTHER: combat fight
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Heterologous Fecal microbiotA Transfer in ICU Patients: a FeasibilitY and SafetY StudY
Status: TERMINATED
Conditions: Intensive Care Units|Fecal Microbiota Transplantation
Interventions: DRUG: fecal microbiota transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Fuling Yunhua Granules and Dihuang Baoyuan Granules in Drug Naive Type 2 Diabetes Patients
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetes|Type2diabetes
Interventions: DRUG: Fuling Yunhua Granules|DRUG: Fuling Yunhua Granules matched placebo|DRUG: Dihuang Baoyuan Granules|DRUG: Dihuang Baoyuan Granules matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Delayed Release Prednisone in PMR
Status: TERMINATED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Delayed-Release (DR) Prednisone|DRUG: Immediate Release (IR) Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Demographic Biases in Deep Learning Model for Fetal Growth Estimation in Clinical Practice. Patients Eligible for Inclusion Are Women with a Gestational Age Between 24-42 Weeks Undergoing a Third-trimester Growth Scan. the Image Data from the Scan Are Used to Calculate Fetal Weight.
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Clofarabine for remission induction|DRUG: Etoposide for remission induction|DRUG: Cyclophosphamide for remission induction|DRUG: Clofarabine in conditioning before transplantation|DRUG: Thiotepa in conditioning before transplantation|DRUG: Melfalan in conditioning before transplantation|PROCEDURE: Haploidentical transplantation of T-cell depleted graft|PROCEDURE: Donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine as a Treatment in Opiate Dependent Pain Patients
Status: TERMINATED
Conditions: Opiate Addiction|Refractory Pain
Interventions: DRUG: buprenorphine/naloxone|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vibration Therapy and Mirror Therapy on Upper Limb Function in Patients With Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: Vibration Therapy (Galileo Dela Interface)|DEVICE: Mirror Therapy ( Mirror Box)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
Status: COMPLETED
Conditions: Diabetes|Effects of Liraglutide Administration on Brain Activity|Weight Loss|Hunger
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)
Status: COMPLETED
Conditions: Hemodynamic Instability|General Anesthesia|Surgery|Protective Mechanical Ventilation
Interventions: DIAGNOSTIC_TEST: Diagnostic Test: end-expiratory occlusion (EEO) test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Prognosis and Progression of Myasthenia Gravis Patients
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: Symptomatic Treatment, Steroids, Immunosuppressive Agents, Plasma Exchange(PE), Intravenous Immunoglobulin(IVIg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Heparin|DRUG: Nadroparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caustic Esophageal Burns in Children and High Doses of Methylprednisolone
Status: COMPLETED
Conditions: Esophageal Diseases
Interventions: DRUG: methylprednisolon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
Status: COMPLETED
Conditions: Labor Pain|Pregnancy
Interventions: PROCEDURE: combined spinal epidural analgesia|PROCEDURE: late analgesia (systemic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Tacrolimus 0.1%|DRUG: Clobetasol 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: L-citrulline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Plant Sterols on Vascular Function
Status: COMPLETED
Conditions: Vascular Diseases|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Plant Sterols|DIETARY_SUPPLEMENT: Placebo Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VelaShape and Contour I V3 for Abdominal Fat Reduction vs. Control
Status: UNKNOWN
Conditions: Unwanted Abdomen Fat
Interventions: DEVICE: VelaShape device|DEVICE: Contour I V3 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Antivirals (GS-5885, Tegobuvir, and/or GS-9451) With Peginterferon Alfa 2a and Ribavirin in Treatment Experienced Subjects With Chronic Genotype 1 Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: GS-5885 tablet|DRUG: GS-9451 tablet|BIOLOGICAL: peginterferon alfa-2a|DRUG: ribavirin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Lisinopril and Hydrochlorothiazide Tablets (20+25) mg Under Fed Conditions
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Lisinopril and Hydrochlorothiazide Tablets (20+25) mg|DRUG: Zestoretic® 20/25 lisinopril/hydrochlorothiazide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AcQMap 2.1 With Electro-Magnetic Tracking System Feasibility Study (EMT Feasibility Study)
Status: COMPLETED
Conditions: Catheter Ablation
Interventions: DEVICE: The AcQMap 2.1 System with Electro-Magnetic Tracking Feasibility System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses
Status: COMPLETED
Conditions: Psychiatric Diagnosis
Interventions: BEHAVIORAL: GamerFit Condition|BEHAVIORAL: Comparator Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of a Mobile Device to Measure Ataxia With High Altitude Exposure
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: AMS Monitor App|OTHER: Lake Louise Score|OTHER: Balance Error Scoring System|OTHER: Heart Rate & Pulse Oxygen Saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: OTHER: Patient Decision Support Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: PR1 leukemia peptide vaccine|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT