pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity (RANSPRE)
Status: RECRUITING
Conditions: Preeclampsia (PE)
Interventions: PROCEDURE: First-trimester preeclampsia screening (FMF triple test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Is Labetalol More Effective Than Metoprolol for Controlled Hypotensive Anesthesia During Endoscopic Nasal Surgeries?
Status: COMPLETED
Conditions: Hypotension Drug-Induced
Interventions: DRUG: Labetalol Hydrochloride Oral Tablet|DRUG: Metoprolol Tartrate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test if the Vaccine is Working Well in Chronic Obstructive Pulmonary Disease (COPD) Patients Aged 40 to 80 Years Old to Reduce Episodes of Worsening Symptoms and to Gather Further Information on Safety and Immune Response.
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: BIOLOGICAL: NTHi Mcat investigational vaccine (GSK3277511A)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Misoprostol for the Healing of Small Bowel Ulcers in Low-dose Aspirin Users Complicated by Small Bowel Bleeding
Status: COMPLETED
Conditions: Ulcer Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Systemic Steroids for Peripheral Nerve Blocks
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine|DRUG: Epinephrine|PROCEDURE: Lumbar Plexus Nerve Block|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Finger Flexor Tendon Injuries
Status: RECRUITING
Conditions: Flexor Tendon Rupture
Interventions: OTHER: Manchester Short Splint|OTHER: Relative Motion Flexion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Patients With Neuropathic Pain From Post-Herpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: GEn 1200mg/day|DRUG: GEn 2400mg/day|DRUG: GEn 3600mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Ipratropium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Subacute and Chronic Iliofemoral DVT
Status: RECRUITING
Conditions: Iliofemoral; Thrombosis
Interventions: COMBINATION_PRODUCT: Perivascular dexamethasone|COMBINATION_PRODUCT: Perivascular sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Response to Intervention (RTI) for Students With ADHD
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Tier 1 Classroom Management|BEHAVIORAL: Daily Report Card (DRC)|BEHAVIORAL: Enhanced DRC (DRC-E)|DRUG: Stimulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Placebo|BIOLOGICAL: Tralokinumab Dose 1|BIOLOGICAL: Tralokinumab Dose 2|BIOLOGICAL: Tralokinumab Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
Status: RECRUITING
Conditions: Psychotic Disorders|Bipolar Disorders|Suicidal Ideation|Suicide, Attempted
Interventions: BEHAVIORAL: SUicide Prevention by Peers Offering Recovery Tactics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation Of The Effect Of Steady State Filibuvir On The Pharmacokinetics Of Oral Contraceptives (Levonorgestrel And Ethinyl Estradiol)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: filibuvir + Oral Contraceptives
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: COVID-19 Brain Injury
Status: COMPLETED
Conditions: Sars-CoV2|Severe Neurologic Injury|Ischemic Stroke|Hemorrhagic Stroke|Intracerebral Hemorrhage|Subarachnoid Hemorrhage|Traumatic Brain Injury|Status Epilepticus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Paraprobiotic Lactobacillus Plantarum IS-10506 on Humoral Immune Response of Elementary School Children
Status: COMPLETED
Conditions: Humoral Immune Response
Interventions: DIETARY_SUPPLEMENT: UHT Milk + Lactobacillus plantarum IS-10506|DIETARY_SUPPLEMENT: UHT Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Synbiotic Therapy of Gastrointestinal Symptoms During Covid-19 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID
Interventions: DIETARY_SUPPLEMENT: Omnibiotic AAD|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pivotal Bioequivalence Study Between Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test Product|DRUG: Reference Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lipid-lowering Effect of Phytosterols, Red Yeast Rice and Their Combination
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Plant sterols|DIETARY_SUPPLEMENT: Red Yeast Rice|DIETARY_SUPPLEMENT: Red Yeast Rice plus Plant sterols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Liraglutide in Healthy Japanese Volunteers
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: liraglutide|DRUG: liraglutide|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel, Gemcitabine, and Bevacizumab in Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Nab-paclitaxel|DRUG: Bevacizumab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Resistant Depression in Bipolar Disorder - A Randomized Controlled Trial of Electroconvulsive Therapy
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: PROCEDURE: Electroconvulsive therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Obeticholic acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis
Status: COMPLETED
Conditions: Cervical Dystonia|Spasmodic Torticollis
Interventions: DRUG: BOTULINUM TOXIN TYPE B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Early Powered Mobility for Toddlers With Cerebral Palsy Using the Permobil® Explorer Mini and a Modified Ride-On Car
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Permobil Explorer Mini|DEVICE: Modified Ride-On Car
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Safety, Tolerability, and Efficacy of 5-ALA-Phosphate + SFC as an Immune System Enhancer Along With Vaccination Against COVID-19
Status: WITHDRAWN
Conditions: SARS-COV 2|Covid19
Interventions: DIETARY_SUPPLEMENT: 5-ALA-Phosphate + SFC (5-ALA+SFC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: AMT-162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement
Status: RECRUITING
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: Albumin Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Stellate Ganglion Block in Dysphagic Patients With Bulbar Palsy After Ischemic Stroke
Status: WITHDRAWN
Conditions: Bulbar Palsy
Interventions: BEHAVIORAL: Comprehensive rehabilitation|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autoimmune Intervention Mastery Course Study
Status: RECRUITING
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome|Fibromyalgia|Post Acute Sequelae of COVID-19|Cancer in Remission With Persisting Fatigue
Interventions: BEHAVIORAL: Immediate Autoimmune Intervention Mastery Course (AIM)|BEHAVIORAL: Immediate Question and Answer sessions. (AIM Q and A sessions)|BEHAVIORAL: Delayed Autoimmune Intervention Mastery Course (delayed AIM course)|BEHAVIORAL: Delayed AIM Question and Answer sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photodynamic Therapy (PDT) With Temoporfin for Non-Resectable Non-Small-Cell Lung Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell-Lung
Interventions: DRUG: Temoporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea
Status: COMPLETED
Conditions: Maturity-Onset Diabetes of the Young, Type 3
Interventions: DRUG: Glimepiride 1Mg Tablet|DRUG: Glucagon-like Peptide-1|DRUG: Glucose-Dependent Insulinotropic Polypeptide|DRUG: Placebo Oral Tablet|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Herniorrhaphy Study for Opioid Elimination
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: HTX-011|DEVICE: Luer lock applicator|DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Sacituzumab tirumotecan|BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Capecitabine|DRUG: Liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UH3 Phase - Mindfulness-Based Blood Pressure Reduction (MB-BP) : Stage 2a RCT
Status: COMPLETED
Conditions: Hypertension|Prehypertension
Interventions: BEHAVIORAL: MB-BP|OTHER: Enhanced Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Anaplastic Oligoastrocytoma|Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant|Glioblastoma|Gliosarcoma
Interventions: DRUG: Adavosertib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tracking Triple-negative Breast Cancer Evolution Through Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple-Negative Breast Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biopsy (optional)|PROCEDURE: Biopsy (metastatic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cyclophosphamide and Fludarabine to Treat Lupus Nephritis
Status: COMPLETED
Conditions: Glomerulonephritis|Lupus Nephritis|Systemic Lupus Erythematosus
Interventions: DRUG: SQ Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Operative Correction of Rectus Muscle Diastasis (ARD): the Effect on Low Back Pain and Movement Control
Status: UNKNOWN
Conditions: Diastasis Recti
Interventions: PROCEDURE: Suture repair|PROCEDURE: Rolled mesh repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Ketoprofen Oral Gel vs Ketoprofen Lysine Salt as Granules for Oral Solution
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ketoprofen Lysine|DRUG: Ketoprofen Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: US Guided Axillary Block With Only One Injection
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Ultrasound guided axillary plexus block with 1 injection|PROCEDURE: Ultrasound guided axillary plexus block with 2 injections|DRUG: lidocaine 1.5% with epinephrine 5µg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Histamine H3 Receptor Occupancy of TS-091 by PET Examination in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TS-091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Thalassemia Major
Interventions: DEVICE: CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Continuous Passive Motion on the Spinal Circuitries and Its Adaptation in Patients With Spasticity Resulting From Upper Motor Neuron Lesions
Status: COMPLETED
Conditions: Spinal Cord Injury(SCI)
Interventions: PROCEDURE: Ankle continuous passive motion machine.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit
Status: COMPLETED
Conditions: Intracranial Pressure|Traumatic Brain Injury|Stroke|Intracranial Hemorrhages
Interventions: DEVICE: Echodia® hand-held equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study of Ibrutinib (PCI-32765) in Chinese Participants With Relapse or Refractory Waldenstrom's Macroglobulinemia (WM)
Status: COMPLETED
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Omalizumab in Adults (18-70 Years) With Moderate to Severe Chronic Urticaria
Status: COMPLETED
Conditions: Chronic Urticaria
Interventions: DRUG: Omalizumab 75-375 mg|DRUG: Placebo to omalizumab|DRUG: Loratadine|DRUG: Clemastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remimazolam on Postoperative Delirium
Status: RECRUITING
Conditions: General Anesthetic Drug Adverse Reaction
Interventions: DRUG: remimazolam|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Coenzyme Q10 Treatment on the Mitochondrial Dysfunction and Oxidative Stress Associated to Atherothrombosis Developement in Antiphospholipidid Syndrome Patients
Status: UNKNOWN
Conditions: Coenzyme Q10 on Athero-thrombosis in APS Patients
Interventions: DRUG: CoQ10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Histological Improvement of NASH With Prebiotic
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Prebiotic oligofructose|DIETARY_SUPPLEMENT: Placebo maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Stretching Techniques on Extensibility, Strength and Range of Motion in Football Athletes
Status: UNKNOWN
Conditions: Asymptomatic Condition
Interventions: OTHER: Dynamic stretching|OTHER: Passive stretching|OTHER: Self-stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel for Mandibular Anterior Gingival Recession Defects
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Group A The Laterally Closed Tunnel Technique with SCTG|PROCEDURE: Group B Modified Coronally Advanced Tunnel Technique with SCTG.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C-MAC Videolaryngoscope for Insertion of a Transesophageal Echocardiography Probe in ICU Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: DEVICE: Blind insertion technique|DEVICE: C-MAC videolaryngoscope insertion technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Group-based Cardiac Rehabilitation on Patients With Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Post-cardiac Surgery
Interventions: OTHER: MICT with Aerobic exercise on treadmill|OTHER: standard hospital protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Cough Assist Device On Hemodynamic Status And Oxygen Saturation For Ventilated Children
Status: COMPLETED
Conditions: Pneumonia Childhood|Intensive Care Unit|Children
Interventions: DEVICE: Cough assist device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Urinary Bactericidal Activity of 4 Doses of Levofloxacin Against Fluoroquinolone-Resistant E. Coli
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: levofloxacin at 250, 500, 750, and 1000 mg doses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotid Stenting in Patients With High Risk Carotid Stenosis ("Soft Plaque")
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: DEVICE: carotid stenting with MOMA|DEVICE: Carotid stenting with filter wire EZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Orthostatic Hypertension|Cognitive Change|Cognitive Impairment|Cognitive Decline
Interventions: DIAGNOSTIC_TEST: Head-up tilt table
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Age-related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: lutein|DIETARY_SUPPLEMENT: Lutein|DIETARY_SUPPLEMENT: placebo|DRUG: Lutein and zeaxanthin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modification of Cerebral Activity of Obsessive Compulsive Disorder (OCD) Patients During Cognitive and Behavioral Therapy
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive and behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)
Status: RECRUITING
Conditions: Intracranial Hemorrhages|Atrial Fibrillation
Interventions: DRUG: Edoxaban|OTHER: Non-anticoagulant medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incidences of Cuff-related Trauma After Noninvasive Blood Pressure Measurement Between With and Without Padding
Status: COMPLETED
Conditions: Complication
Interventions: DEVICE: Padding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular Inflammation
Status: UNKNOWN
Conditions: Endothelial Dysfunction|Vascular Inflammation
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Sleep Apnea
Interventions: PROCEDURE: Continuous positive airway pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Food4GutMarKIT - Evaluation of a Tailored Personalized Food Concept for a Healthy Gut Microbiota and Validation of Biomarkers for Monitoring of Its Effects
Status: COMPLETED
Conditions: Healthy, Overweight, Obese
Interventions: OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Almond on Facial Skin Collagen and Wrinkles
Status: RECRUITING
Conditions: Collagen Degeneration|Wrinkle|Pigmentation|Elastic Skin
Interventions: OTHER: Food: whole almonds|OTHER: Food: non-nut snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotid Duplex Ultrasound for Selecting Patients for Endovascular Thrombectomy in Acute Stroke Patients
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: PROCEDURE: After detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: LY3857210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Prehabilitation for Colorectal Surgery
Status: COMPLETED
Conditions: Prehabilitation|Colorectal Surgery|Enhanced Recovery After Surgery
Interventions: COMBINATION_PRODUCT: Prehab|OTHER: ERAS|BEHAVIORAL: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Bradykinin Antagonists on Pulmonary Manifestations of COVID-19 Infections (AntagoBrad-Cov Study).
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: C1 Inhibitor Human|DRUG: Icatibant Injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Dronedarone (SR33589)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Octacosanol During Taekwondo Training
Status: COMPLETED
Conditions: Oxidative Stress|Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Octacosanol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Panobinostat With Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Panobinostat with Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis
Status: UNKNOWN
Conditions: Tuberculosis|Psoriasis
Interventions: OTHER: Tuberculin skin test and Quantiferon -TB Gold test
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ingestion Effect of Formula Milk With Triple Bifidobacteria Strains on Fecal Quality and Metabolites in Healthy Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Children, Only
Interventions: COMBINATION_PRODUCT: Formula milk with triple Bifidobacterium probiotic strain|OTHER: Formula milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study of Intraperitoneal T3011 Given as a Single Agent in Patients With Malignant Ascites Induced by Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Malignant Ascites
Interventions: DRUG: T3011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Hemodialysis Session on Vascular Stiffness
Status: COMPLETED
Conditions: Arteriopathic Disease|Arterial Calcification|Complication of Hemodialysis|Aortic Stiffness
Interventions: DEVICE: Complior Analyse System|DEVICE: BCM- Body Composition Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
Status: RECRUITING
Conditions: Sickle Cell Disease|Hemoglobinopathies
Interventions: GENETIC: EDIT-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: MIST Therapy|OTHER: SOC - Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of an H.Pylori Vaccine in H.Pylori-Negative Adults
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: BIOLOGICAL: H.pylori vaccines|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Induction and Concurrent Chemoradiotherapy With Cetuximab for Patients With Locally Advanced Nasopharyngeal Carcinoma
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wide Diameter Bone Anchored Implant Study
Status: COMPLETED
Conditions: Conductive Hearing Loss|Conductive and Sensori-neural Hearing Loss in the Same Ear|Unilateral, Profound Sensori-neural Hearing Loss
Interventions: DEVICE: Wide diameter bone anchored implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Relationship Exist Between Fetal Hiccups and Computerised Cardiotocography Parameters?
Status: COMPLETED
Conditions: Fetal Conditions|Fetal Movement Disorder
Interventions: DIAGNOSTIC_TEST: Fetal heart rate (FHR) monitoring through computerized cardiotocography (cCTG) analysis antepartum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SOLUTION Trial in China
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Calcifications Vascular
Interventions: DEVICE: Shockwave Medical Peripheral Intravascular Lithotripsy (IVL) System M5 & S4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose Pharmacokinetics Study of Two Gefapixant (AF-219/MK-7264) Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omeprazole|DRUG: Gefapixant|DRUG: Gefapixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Randomized, Double-Blinded, Placebo-Controlled Study of ARQ 197 Plus Erlotinib Versus Placebo Plus Erlotinib
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: ARQ 197 and Erlotinib|DRUG: Placebo and Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combating Hospital-related Function Decline Among Prefrail Older Adults: A Pilot Study
Status: RECRUITING
Conditions: Frailty|Geriatrics
Interventions: BEHAVIORAL: STEP@Home Intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: More Individualized Care: Assessment and Recovery Through Engagement
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety|Opioid-Related Disorders|Pain, Chronic
Interventions: BEHAVIORAL: More Individualized Care: Assessment and Recovery through Engagement (MI-CARE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helmet Noninvasive Ventilation vs. High-flow Nasal Cannula in Moderate-to-severe Acute Hypoxemic Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Failure With Hypoxia
Interventions: DEVICE: Noninvasive respiratory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Performance of Inlay Zirconia Bridges
Status: COMPLETED
Conditions: Dental Crowns
Interventions: PROCEDURE: Glaze layer|PROCEDURE: E-max Press layer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P. Knowlesi Trial of Artesunate-mefloquine Versus Chloroquine
Status: COMPLETED
Conditions: Uncomplicated Plasmodium Knowlesi Malaria
Interventions: DRUG: Artesunate-mefloquine|DRUG: Chloroquine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electromyostimulation on Bone
Status: COMPLETED
Conditions: Osteopenia|Sarcopenia|Falls
Interventions: OTHER: wellness control group.|DEVICE: whole-body electromyostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Fortified Beverages and Application in Women Predisposed to Anemia
Status: COMPLETED
Conditions: Iron-deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: non-fortified fruit juices consumed as part of the usual diet|DIETARY_SUPPLEMENT: Iron fortified fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Intravenous Iron Versus Placebo On Muscle Oxidative Capacity And Physical Performance in Premenopausal Women
Status: COMPLETED
Conditions: Non Anemic Patients With Iron Deficiency (Low Ferritin Value)
Interventions: DRUG: intravenous iron carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Labor Scale Versus WHO Partograph for Management of Labor (ScaLP)
Status: UNKNOWN
Conditions: Dystocia
Interventions: PROCEDURE: Amniotomy|DRUG: Oxytocin|PROCEDURE: Cesarean Section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: INSTANT: INtegrilin Plus STenting to Avoid Myocardial Necrosis Trial
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: eptifibatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pregabalin (Lyrica) for the Treatment of Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME).
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773 low dose|DRUG: Placebo BI 10773 high dose|DRUG: BI 10773 high dose|DRUG: Placebo BI 10773 low dose|DRUG: Placebo BI 10773 low dose|DRUG: Placebo BI 10773 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Jawbone Anatomy Classification in Endosseous Dental Implant Treatment
Status: UNKNOWN
Conditions: Partially Edentulous Jaw
Interventions: RADIATION: Cone-Beam Computed Tomography preoperative evaluation.|PROCEDURE: Intraoperative edentulous jaw segment parameters evaluation.|DEVICE: Endosseous dental implant placement.|RADIATION: Dental implant position evaluation.|DRUG: Medications.|PROCEDURE: Late postoperative soft tissue evaluation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Period Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Status: COMPLETED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: Dasiglucagon|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venous Sinus Stenting To Treat Intractable Pulsatile Tinnitus Caused By Venous Sinus Stenosis
Status: TERMINATED
Conditions: Tinnitus|Pulsatile Tinnitus|Venous Sinus Stenosis|Dural Sinus Stenosis
Interventions: DEVICE: Venous Sinus Stenting with the Precise Pro Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kidney Damage in Patients With Moderate Fall in eGFR
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: DRUG: Iopamidol|DRUG: Iodixanol-320
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: DRUG: Celecoxib|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Hernia|Anesthetics Adverse Reaction|Inflammation
Interventions: PROCEDURE: local anesthesia group|PROCEDURE: spinal anesthesia group|PROCEDURE: general anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography as a Single Tool for Guided Percutaneous Transhepatic Biliary Drainage in Obstructive Jaundice
Status: UNKNOWN
Conditions: Obstructive Jaundice
Interventions: DEVICE: nephrostomy set
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relationship Checkups to Reduce Veteran Suicide Risk
Status: RECRUITING
Conditions: Relationship Distress|Mental Health
Interventions: BEHAVIORAL: Brief Relationship Checkup (BRC)|BEHAVIORAL: Co-Located Collaborative Care (CCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Laser and Topical Treatment Combination in the Vulvo-vaginal Atrophy Management in Breast Cancer Patients.
Status: NOT_YET_RECRUITING
Conditions: Female Urogenital Diseases|Breast Cancer Female
Interventions: DEVICE: C02 microablative laser|COMBINATION_PRODUCT: Regenerative topical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prospective Study on the Effect of Ilaprazole in Non-erosive Reflux Disease Patients; Focused on Histologic Findings and Inflammatory Biomarker
Status: COMPLETED
Conditions: Gastrointestinal Subepithelial Tumors
Interventions: DRUG: Ilaprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pacifier Activated Lullaby in VLBW Preterm Infants
Status: COMPLETED
Conditions: Music Therapy
Interventions: DEVICE: The effects of Pacifier Activated Lullaby in very low birth weigt preterm infants. An italian music therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Maxillary Repositioning With bi or Tripartite Disjonction by Virtual Planning in Orthognathic Surgery Using Patient-specific Titanium Plates
Status: COMPLETED
Conditions: Occlusal Trauma
Interventions: PROCEDURE: bimaxillair osteotomy with maxillar segmentation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of 5-FU, Oxaliplatin Plus Dasatinib in Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer Metastatic
Interventions: DRUG: Dasatinib|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Systemic Inflammation After Cardiac Surgery With Alkaline Phosphatase
Status: RECRUITING
Conditions: Systemic Inflammation|Cardiopulmonary-bypass
Interventions: DRUG: RESCAP®|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Nasal Spray Hypertonic Puressentiel on Symptoms of Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: OTHER: nasal hypertonic spray: combination of hypertonic sea water and organic rosemary floral water with essential oils (ravintsara, geranium, eucalyptus radiata, niaouli)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer
Status: WITHDRAWN
Conditions: ATM Gene Mutation|Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|Homologous Recombination Deficiency|Pancreatic Ductal Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Epacadostat|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Dose Study for Relapsed/Refractory Hodgkin/Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma|Hodgkin Lymphoma|Lymphoma
Interventions: RADIATION: Radiation - Dose Level 0|RADIATION: Radiation - Dose Level 1|RADIATION: Radiation - Dose Level 2|RADIATION: Radiation - Dose Level 3|RADIATION: Radiation - Dose Level 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Ketorolac Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lactobacillus Plantarum PS128 in Self-Reported Insomniacs
Status: COMPLETED
Conditions: Insomnia
Interventions: DIETARY_SUPPLEMENT: PS128|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Transcranial Focused Ultrasound for the Treatment of Neurodegenerative Dementias
Status: ENROLLING_BY_INVITATION
Conditions: Mild Cognitive Impairment|Mild Dementia|Parkinson Disease|Alzheimer Disease
Interventions: DEVICE: Focused Transcranial Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT