pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Accuracy of the Dexcom G7 Continuous Glucose Monitoring System Following Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Continuous Glucose Monitoring
Interventions: DEVICE: Continuous glucose monitor (CGM) Dexcom G7 used in blinded mode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Implantable Intraocular Pressure Sensor for Glaucoma Monitoring in Patients With Boston Keratoprosthesis Type 1
Status: WITHDRAWN
Conditions: Glaucoma|Blindness, Acquired|Keratitis, Herpetic|Ocular Cicatricial Pemphigoid|Corneal Injuries|Corneal Disease|Corneal Opacity
Interventions: DEVICE: EyeMate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Arsenic Trioxide in Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Cancer of Lung|Pulmonary Cancer|Pulmonary Neoplasms|Carcinoma, Small Cell
Interventions: DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Brainstem Implantation in Young Children
Status: COMPLETED
Conditions: Developmental Cochlear Nerve Deficiency|Acquired Cochlear Nerve Deficiency|Cochlear Aplasia|Post-meningitis Cochlear Ossification|Cochlear Malformation
Interventions: DEVICE: Auditory Brainstem Implantation in Children
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: rituximab|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drinking, Acetate, and Stress
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Use, Unspecified|Heavy Drinker|Alcohol Use Disorder, Moderate, in Sustained Remission
Interventions: OTHER: Deuterium Metabolic Imaging with deuterated acetate tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of VX-445 Combination Therapy in CF Subjects Homozygous for F508del (F/F)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-445/TEZ/IVA|DRUG: TEZ/IVA|DRUG: IVA|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Single Dose Anti-thymocyte Globulin in the Modulation of T Lymphocytes in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Immunosuppression
Interventions: DRUG: single dose of Anti-thymocyte globulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility and Safety Study Using Preoperative High-Dose Single-Fraction Image-Guided Radiotherapy for Men Undergoing Radical Prostatectomy at High-Risk for Extraprostatic Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: High-Dose Single-Fraction Image-Guided Radiotherapy for Men Undergoing Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anti HIV Drugs Used Alone or in Combination With Cytosine Arabinoside to Treat Progressive Multifocal Leukoencephalopathy (PML) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Filgrastim|DRUG: Cytarabine|DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Oxygenation|Ventilation
Interventions: DEVICE: Oxygen via nasal cannula|DEVICE: Oxygen via SuperNO2VA nasal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Called ARAMON to Learn to What Extent Does Study Treatment With Darolutamide Affects Testosterone Levels in Men With Prostate Cancer That Had Not Been Treated With Hormonal Therapy Compared to Treatment With Enzalutamide
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Cancer
Interventions: DRUG: Darolutamide(BAY1841788, Nubeqa)|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle
Status: COMPLETED
Conditions: Pancreatic Cancer|Lymphadenopathy|Gastrointestinal Stromal Tumor
Interventions: DEVICE: Fine needle aspiration|DEVICE: Fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA-Mutated Ovarian Carcinoma|BRIP1 Gene Mutation|MSH2 A636P|MLH1 Gene Mutation|MSH6 Gene Mutation|PMS2 Gene Mutation|EPCAM|RAD51C Gene Mutation
Interventions: OTHER: CASCADE genetic screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: ACP-196|DRUG: ACP-196 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Status: COMPLETED
Conditions: Decay, Dental|Missing Teeth|COVID-19|Cytokine Storm
Interventions: DIAGNOSTIC_TEST: ELISA test for Cytokines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Sinai Robotic Surgery Trial in HPV Positive Oropharyngeal Squamous Cell Carcinoma (SCCA) (SIRS TRIAL)
Status: COMPLETED
Conditions: Human Papilloma Virus|Oropharyngeal Squamous Cell Carcinoma
Interventions: PROCEDURE: PET/CT|RADIATION: Radiotherapy|RADIATION: Concurrent Chemoradiation|RADIATION: Concurrent Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Ketosteril®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Intravenous Tranexamic Acid During Myomectomy
Status: COMPLETED
Conditions: Hemorrhage/Blood Loss During Myomectomies|Fibroids
Interventions: DRUG: Tranexamic Acid|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gulf, Lantus, Apidra Evaluation in Type 1 Diabetics Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: insulin glargine|DRUG: insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging - Synthetic Aperture Magnetometry (fMRI-SAM) and Alzheimer's Disease
Status: WITHDRAWN
Conditions: Alzheimer's Disease
Interventions: PROCEDURE: fMRI to detect MCI patients who will convert to Alzheimer's disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: COVID19 Vaccine in SOT Adult Recipients
Status: COMPLETED
Conditions: COVID-19|Vaccine Adverse Reaction|Vaccine Response Impaired|Vaccine Reaction|Lung Transplant; Complications|Liver Transplant; Complications|Vaccination
Interventions: BIOLOGICAL: COVID19 mRNA vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Infrapatellar Fat Pad Preservation Versus Resection on Clinical Outcomes After Total Knee Arthroplasty(IPAKA)
Status: RECRUITING
Conditions: Knee Osteoarthritis|Arthropathy of Knee
Interventions: PROCEDURE: Infrapatellar Fat Pad preservation|PROCEDURE: Infrapatellar Fat Pad resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Bursectomy and D2 Lymphadenectomy vs.Laparoscopic D2 Lymphadenectomy in Advanced Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer Stage II|Gastric Cancer Stage III
Interventions: PROCEDURE: Laparoscopic bursectomy and D2 lymphadenectomy|PROCEDURE: Laparoscopic D2 lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postural and Clinical Outcomes of SNAGs Treatment in Cervicogenic Dizziness Patients: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Cervicogenic Dizziness|Rehabilitation
Interventions: PROCEDURE: SNAGs Treatment|PROCEDURE: Sham Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RSA Study of Persona TKA With CR vs MC Polyethylene
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Medial Congruent Polyethylene (MC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Malaria Vaccines AdCh63 AMA1, MVA AMA1 and AMA1-C1/Alhydrogel®+/- CPG 7909
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 AMA1 + MVA AMA1 + AMA1-C1/Alhydrogel®+ CPG 7909|BIOLOGICAL: AdCh63 AMA1 + AMA1-C1/Alhydrogel®+ CPG 7909|BIOLOGICAL: AdCh63 AMA1 + AMA1-C1/Alhydrogel®|BIOLOGICAL: AdCh63 AMA1 AMA1-C1/Alhydrogel®+ CPG 7909|BIOLOGICAL: AdCh63 AMA1 + MVA AMA1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Cosmetic Color Tinted Contact Lenses on the Ocular Surface
Status: COMPLETED
Conditions: Conjunctival Infections, Irritations and Inflammations|Hypertrophy; Conjunctiva|Corneal Pannus|Corneal Epithelial Wound
Interventions: OTHER: contact lens wear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Methylene Blue Intradermal Injection for Sentinel Lymph Node Biopsy for Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer Female|Early-Stage Breast Cancer|Sentinel Lymph Node
Interventions: DEVICE: methylene blue intradermal injection|DEVICE: methylene blue subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
Status: RECRUITING
Conditions: Obstetric Pain|Labor Pain|Anesthesia
Interventions: PROCEDURE: Dural puncture epidural|PROCEDURE: Standard epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
Status: RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Dasatinib|DRUG: Darolutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Preliminary Efficacy Study of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia and Treatment-naïve Participants Not Eligible for Intensive Therapy
Status: TERMINATED
Conditions: Leukemia, Myeloid
Interventions: DRUG: CC-90011|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Venetoclax|DRUG: CC-90011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab & Ibrutinib + Allogeneic Bone Marrow Transplant or Consolidation in High Risk Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphoblastic, Chronic
Interventions: DRUG: Ibrutinib + ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing World Study for RotaTeq™ (V260-015)(COMPLETED)
Status: COMPLETED
Conditions: Vomiting|Diarrhea|Fever
Interventions: BIOLOGICAL: RotaTeq™ - Rotavirus Vaccine, Live, Oral, Pentavalent|BIOLOGICAL: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of High-flow Nasal Oxygen on Extubation Outcome
Status: UNKNOWN
Conditions: Respiratory Failure|Congestive Heart Failure|COPD
Interventions: DEVICE: high flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Fatty Acids and Atrial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DIETARY_SUPPLEMENT: omega 3 fatty acids|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Repeated GON Injections in CCH
Status: RECRUITING
Conditions: Cluster Headache
Interventions: DRUG: Methylprednisolone|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin in Young Psychotic Patients
Status: COMPLETED
Conditions: Psychosis|Acute Psychosis|Schizophrenia
Interventions: DRUG: Aspirin|DRUG: Placebo|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Cystocele Plication Risks ("CPR Trial"): A Pilot Study
Status: COMPLETED
Conditions: Voiding Dysfunction
Interventions: PROCEDURE: Cystocele plication|PROCEDURE: No Plication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetic Study Between HLX02 and Herceptin®(U.S. and German Sourced) in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HLX02|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Foley Catheter Balloon With Early Amniotomy for Induction of Labor at Term
Status: COMPLETED
Conditions: Induced Vaginal Delivery
Interventions: PROCEDURE: early amniotomy|DEVICE: foley catheter balloon placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Lurbinectedin and Dostarlimab in Cancer Patients: Protocol VHIO21001 - LiDer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Lurbinectedin|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Periodontal Infections
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: scaling and root planing|DRUG: local tetracycline|DRUG: systemic metronidazole and amoxicillin|OTHER: surgery|DRUG: local antibiotics and systemic metronidazole and amoxicillin|OTHER: local tetracycline and periodontal surgery|OTHER: periodontal surgery and systemic metronidazole and amoxicillin|OTHER: surgery, local tetracycline, systemic metronidazole and amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Status: COMPLETED
Conditions: CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Interventions: DRUG: 0.9% saline|DRUG: 0.25% bupivacaine hydrochloride injectable suspension USP|DRUG: 4mg/cc methylprednisolone acetate injectable suspension USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicenter Dose Finding Phase II Pilot Trial to Evaluate Efficacy and Safety of LR-CHOP21 for Elderly Patients With Untreated Diffuse Large B Cell Lymphoma
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma|Follicular Lymphoma
Interventions: DRUG: LR-CHOP21
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Stabilizing Splint (Michigan-type Occlusal Splint) Versus Anterior Repositioning Splint .
Status: UNKNOWN
Conditions: TMJ Disc Disorder
Interventions: DEVICE: Stabilizing splint|DEVICE: Anterior repositioning splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: eMurmur ID - Clinical Performance Evaluation
Status: COMPLETED
Conditions: Heart Murmurs|Pathologic Murmurs|Innocent Murmurs|Congenital Heart Defect|Systolic Murmurs|Diastolic Murmurs
Interventions: DEVICE: Automated Heart Murmur Detection AI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants
Status: TERMINATED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: sabatolimab|DRUG: azacitidine|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection
Interventions: BIOLOGICAL: Feacal microbial transplantation (FMT)|OTHER: Placebo transplantation (PT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gamma-Induction in FrontoTemporal Dementia Trial
Status: RECRUITING
Conditions: Frontotemporal Dementia
Interventions: DEVICE: Transcranial Alternating Current Stimulation (tACS)|DEVICE: Sham Transcranial Alternating Current Stimulation (sham tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal, Neonatal and Infant Outcomes at Kawempe National Referral Hospital
Status: ACTIVE_NOT_RECRUITING
Conditions: Group B Streptococcus Carrier in Childbirth|Group B Streptococcal Infection, Late-Onset|Group B Streptococcal Infection, Early-Onset|Group B Streptococcus Neonatal Sepsis|Group B Strep Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Maintenance Treatment With rhTPO in Thrombocytopenic Subjects With ITP
Status: UNKNOWN
Conditions: Thrombocytopenia|Immune Thrombocytopenia|Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin to Avoid Component Separation in Midline Large Hernias
Status: COMPLETED
Conditions: Botulinum Toxin Type A|Rives Repair|Large Midline Hernia|Component Separation
Interventions: PROCEDURE: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Trial to Evaluate Zanubrutinib Combined With BR (Bendamustine/Rituximab) Regimen in Subjects With Newly-diagnosed Waldenström's Macroglobulinemia
Status: RECRUITING
Conditions: Waldenström's Macroglobulinemia
Interventions: DRUG: Zanubrutinib|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Equivalence of MSB11455 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MSB11455|DRUG: Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma|Pleural Mesothelioma
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Novel Method of Generalizing Emotion Regulation
Status: COMPLETED
Conditions: Problems With Emotion Regulation|Psychological Distress|Difficulties Coping With Negative Emotions|Anxiety|Depression|Borderline Personality Disorder
Interventions: BEHAVIORAL: Habituation Reminder Training|BEHAVIORAL: Habituation Reminder|BEHAVIORAL: Habituation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest of Functional Neuroimaging in Assessing Decision-making Capacity of Older People With Neurocognitive Disorders
Status: UNKNOWN
Conditions: Decision Making|Dementia|Aging
Interventions: DIAGNOSTIC_TEST: Geriatric Assesment with neuropsychological test more specific on decision making|DIAGNOSTIC_TEST: Functional RMI|DIAGNOSTIC_TEST: High Resolution EEG|OTHER: Qualitative interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proprioceptive Neuromuscular Facilitation Techniques in Patients With Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis|Shoulder Pain|Shoulder Frozen
Interventions: OTHER: Proprioceptive Neuromuscular Facilitation Exercises|OTHER: Conventional Rehabilitation Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.
Status: COMPLETED
Conditions: Left Ventricular Diastolic Dysfunction
Interventions: DRUG: BNP (nesiritide)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Safety and Efficacy of MGCND00EP1 as an Add on Treatment in Children and Adolescents With Resistant Epilepsies
Status: WITHDRAWN
Conditions: Resistant Epilepsy, Drug|Adolescent Epilepsy|Children Epilepsy|Children and Adolescents With Resistant Epilepsies
Interventions: DRUG: MGCND00EP1|DRUG: Placebo|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: EEG|DIAGNOSTIC_TEST: Blood and urine collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Axonics SacRal NeuromodulaTIon System for Urinary Urgency Incontinence TreatmeNt
Status: COMPLETED
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: Axonics Sacral Neuromodulation System (SNM) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIST Ultrasound Therapy Compared to United Kingdom Standard Care for the Treatment of Non-healing Venous Leg Ulcers
Status: COMPLETED
Conditions: Varicose Ulcer
Interventions: DEVICE: MIST ultrasound therapy|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Lentils on Metabolism and Inflammation
Status: COMPLETED
Conditions: Hypertriglyceridemia|Inflammation|Waist, Hypertriglyceridemic
Interventions: BEHAVIORAL: Dietary Lentil|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Migration Rates of Sutured vs Non-sutured Esophageal Stent Placement
Status: COMPLETED
Conditions: Dysphagia, Esophageal|Esophageal Cancer
Interventions: OTHER: Suture fixation of stent|OTHER: Non suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Treatment Efficacy of Two Syntactic Treatment Procedures for Children With Specific Language Impairment (SLI): A Randomized Controlled Trial
Status: COMPLETED
Conditions: Language Impairment in School-years
Interventions: BEHAVIORAL: Syntax treatment via sentence-combining method|BEHAVIORAL: Syntax treatment managed by narrative-based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Endoscopic Papillectomy With Stent for Treating Duodenal Papillary Adenoma
Status: COMPLETED
Conditions: Duodenal Adenoma|Complication of Treatment
Interventions: PROCEDURE: Stent Placement in Pancreatic and Bile Ducts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SMART Optimization of a Parenting Program for Active-duty Families
Status: COMPLETED
Conditions: Parenting
Interventions: BEHAVIORAL: Phase 1: ADAPT Workshop|BEHAVIORAL: Phase 1: ADAPT Online|BEHAVIORAL: Phase 2: ADAPT Group|BEHAVIORAL: Phase 2: ADAPT Individual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fractional Microplasma Radiofrequency Technology for Non-hypertrophic Post-burn Scars in Asians: A Prospective Study of 95 Patients
Status: COMPLETED
Conditions: Cicatrix
Interventions: PROCEDURE: Fractional micro-plasma radiofrequency treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cordyceps Sinensis and Lingzhi on Cardiovascular Fitness and Cognitive Function
Status: UNKNOWN
Conditions: Physical Fitness|Executive Function
Interventions: DIETARY_SUPPLEMENT: Cordyceps Sinensis (CS) and Lingzhi|DIETARY_SUPPLEMENT: Tea and Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: ERBITUX® Followed by Adjuvant Treatment With Chemoradiation and ERBITUX® for Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cetuximab|PROCEDURE: Surgery|RADIATION: Post-surgical radiation|DRUG: Cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-exercise-fatigue Effects of Rice Protein RP-80NY in Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: rice protein RP-80N|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Training and Energy Management Education to Improve Quality of Life in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Endurance Training|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians in Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DIAGNOSTIC_TEST: NT-proBNP|DIAGNOSTIC_TEST: AI echocardiogram|DIAGNOSTIC_TEST: electrocardiogram|OTHER: Cardiovascular physical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release)
Status: COMPLETED
Conditions: Pain|Analgesics, Opioid
Interventions: DRUG: OROS hydromorphone HCI CR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years
Status: COMPLETED
Conditions: Dental Caries in Children|Pediatric Dental Sedation|Meperidine|Hydroxyzine|Midazolam
Interventions: DRUG: Meperidine|DRUG: Hydroxyzine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy in Removal of Advanced Glycation End Products (AGEs) Between Super High-flux Hemodialysis and Postdilution Online Hemodiafiltration: A Single-center, Prospective, Open-label, Crossover Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease
Interventions: DEVICE: super high-flux hemodialysis|DEVICE: postdilution online hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-way Texting (2wT) to Improve Antiretroviral (ART) Patient Retention in Malawi
Status: ACTIVE_NOT_RECRUITING
Conditions: Retention in Care
Interventions: OTHER: two way texting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intermittent Preventive Treatment for Malaria in Patient With Sickle Cell Disease
Status: COMPLETED
Conditions: Malaria|Sickle Cell Crisis
Interventions: DRUG: Proguanil|DRUG: mefloquine plus artesunate|DRUG: Sulfadoxine-pyrimethamine plus amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris
Status: UNKNOWN
Conditions: Acne
Interventions: DRUG: Doxycycline|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BPT to Improve Bodily Disturbances in Post-treatment Cancer Patients
Status: COMPLETED
Conditions: Cancer Patients
Interventions: BEHAVIORAL: BPT|BEHAVIORAL: Smartphone-triggered bodily interventions|BEHAVIORAL: Smartphone triggered control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simeox Therapy at Home Versus Standard of Care in NCFB Patients With CMH
Status: RECRUITING
Conditions: Non-cystic Fibrosis Bronchiectasis|Chronic Mucus Hypersecretion
Interventions: DEVICE: Simeox|COMBINATION_PRODUCT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Recombinant Factor VIIa in Patients With Severe Bleeding
Status: TERMINATED
Conditions: Acquired Bleeding Disorder|Trauma
Interventions: DRUG: eptacog alfa (activated)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non - Small Cell Lung Cancer NSCLC
Interventions: DRUG: MEDI4736 (durvalumab)|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Erlotinib|DRUG: MEDI4736 (durvalumab) in combination with tremelimumab (anti-CTLA4)|DRUG: tremelimumab (anti-CTLA4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
Status: RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: BEHAVIORAL: Smoking Cessation Intervention|OTHER: Health Promotion and Education|OTHER: Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ingenol Mebutate Gel 0.05% in Kidney Transplant Recipients With Actinic Keratoses
Status: TERMINATED
Conditions: Actinic Keratosis
Interventions: DRUG: ingenol mebutate 500 ucg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dental Health Home Visits on Caries Prevention in Young Children
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: BEHAVIORAL: Intervention Group (Dental Home Visits + Dental Home Education Leaflets)|BEHAVIORAL: Control Group (Dental Home Education Leaflets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults
Status: RECRUITING
Conditions: Enterovirus Infection
Interventions: BIOLOGICAL: EV68-228-N|OTHER: Placebo for EV68-228-N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SH-1028
Status: UNKNOWN
Conditions: Healthy Male Volunteers
Interventions: DRUG: SH-1028|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Responders to Rhythmic Auditory Stimulation in Individuals Post-Stroke and Older Adults
Status: RECRUITING
Conditions: Stroke|Old Age
Interventions: DEVICE: Subject-specific optimized RAS|BEHAVIORAL: Active walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Work-life Check-ins: a Supervisor-driven Intervention to Reduce Burnout in Primary Care
Status: RECRUITING
Conditions: Burnout
Interventions: OTHER: Supervisor-employee frequent check-ins to identify and address work stressors|OTHER: Usual practice waitlist controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: idarubicin|DRUG: imatinib mesylate|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: mitoxantrone hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Incidence and Predictors of Developing Atrial Fibrillation in Patients With Inferior ST-segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: holter monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantification of Motor Function in Infants With Spinal Muscular Atrophy Treated With Innovative Therapies
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Motor function measurement using inertial sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Levosimendan Efficacy Assessment by Cardiopulmonary Exercise Test (CPET)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Identification of Immune Determinants for Response to Nivolumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TAK-242 in Patients With Acute Alcoholic Hepatitis
Status: UNKNOWN
Conditions: Acute-On-Chronic Liver Failure
Interventions: DRUG: TAK-242|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Portable Technology in Patient Education of Shave/Punch Biopsies
Status: COMPLETED
Conditions: Biopsy
Interventions: OTHER: video-based informed consent for skin biopsies|OTHER: traditional informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accuracy of Pulse Pressure Variation and of Pleth Variability Index to Predict the Response to a Fluid Challenge
Status: COMPLETED
Conditions: Fluid Responsiveness
Interventions: DEVICE: - Nexfin (Pulse Pressure Variation) - Radical 7 (Pleth Variability Index) - CardioQ (stroke volume)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Is Self-transfusion Safe After Total Knee Arthroplasty in Terms of Nephrotoxicity of Gentamicin From Bone Cement?
Status: COMPLETED
Conditions: Arthroplasty Complications|Total Knee Arthroplasty
Interventions: DEVICE: Self-transfusion device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab in Combination With PLD and Losartan in Patients With TNBC Who Have Received ≦ 1 Line of Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Camrelizumab|DRUG: Liposomal Doxorubicin|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Hypertension
Interventions: DRUG: Placebo|DRUG: Enalapril 5mg|DRUG: Enalapril 10mg|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Default Options in Advance Directives
Status: COMPLETED
Conditions: This Study Will Focus on Advance Care Planning Among Patients With Life-limiting Illnesses
Interventions: BEHAVIORAL: Life-extension default advance directive|BEHAVIORAL: Comfort default advance directive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Diclofenac HPBCD|DRUG: Diclofenac HPBCD|DRUG: Diclofenac HPBCD|OTHER: Placebo s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Replicor Compassionate Access Program
Status: AVAILABLE
Conditions: Viral Hepatitis B|Viral Hepatitis D|Cirrhosis, Liver|Decompensated Cirrhosis|Ascites Hepatic|Varices, Esophageal|Hepatocellular Carcinoma
Interventions: DRUG: REP 2139-Mg|DRUG: Tenofovir Disoproxil Fumarate|DRUG: Pegylated interferon alpha2a
Study Type: EXPANDED_ACCESS
Clinical trial: A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With Chronic Hepatitis B and Hepatitis D Co-infection
Status: TERMINATED
Conditions: Chronic Hepatitis B and Hepatitis D Co-infection
Interventions: BIOLOGICAL: HH-003 20mg/kg|BIOLOGICAL: HH-003 3mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of SPD465 in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: SPD465|DRUG: Immediate Release Amphetamine Salt|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dry Roasted Peanuts and Boiled Peanuts on Glycemic Control
Status: TERMINATED
Conditions: Diabetes Mellitus|Glycemic Control
Interventions: OTHER: Roasted Peanut Treatment|OTHER: Boiled Peanut Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Irinotecan|DRUG: Cetuximab|DRUG: 5-fluorouracil|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Remediation of Black Stain
Status: COMPLETED
Conditions: Dental Deposits|Tooth Discoloration|Dental Prophylaxis
Interventions: PROCEDURE: Dental prophylaxis|DEVICE: Dental prophylaxis + antimicrobial photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy
Status: RECRUITING
Conditions: Ototoxic Hearing Loss
Interventions: DRUG: Sodium Thiosulfate + Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer
Status: UNKNOWN
Conditions: Cancer|Toxicity Due to Chemotherapy|Sarcoma|Osteosarcoma|Lymphoma|Ewing Sarcoma
Interventions: DRUG: Triptorelin (GnRHa) + Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the New Fitting Method Cochlear Nucleus Fitting Software (NFS) With the Established Fitting Method Cochlear Nucleus Custom SoundTM Suite (CSS)
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: NFS|DEVICE: CSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Apnea Treatment in Premature Infants Using an Automatic Vibro-tactile Stimulator Triggered by the Detection of Apnea-bradycardia.
Status: RECRUITING
Conditions: Apnea of Prematurity
Interventions: DEVICE: SENSITACT System|DEVICE: SENSITACT System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Anaprazole Sodium enteric-coated tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Marginal Bone Changes in CAD Metallic and (PEEK) Partial Denture Frameworks
Status: ACTIVE_NOT_RECRUITING
Conditions: Patient Satisfaction
Interventions: OTHER: RPD with PEEK framework|OTHER: RPD with metallic framework
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT