pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Autologous Culture Expanded Mesenchymal Stromal Cells for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Autologous Adipose-Derived Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-protein Oral Supplement Improves Normalized Protein Catabolic Rate and Inflammation Markers
Status: COMPLETED
Conditions: Renal Failure|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DIETARY_SUPPLEMENT: Soy protein isolate|DIETARY_SUPPLEMENT: Whey protein isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Intravenous Iron Supplementation in Reducing Allogenic Blood Transfusion
Status: COMPLETED
Conditions: Complications
Interventions: DRUG: Iron Isomaltoside 1000|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701
Status: WITHDRAWN
Conditions: Metastatic Lung Cancer|Metastatic Breast Cancer|Metastatic Gastric Cancer
Interventions: DRUG: Tusamitamab ravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Status: COMPLETED
Conditions: Cerebral Ischemia
Interventions: DEVICE: NIRS and Algorithm|DEVICE: NIRS derived cerebral oximetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Parenting Stress|Depression|Anxiety
Interventions: BEHAVIORAL: laughter yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy Combined With Adebrelimab and Mecapegfilgrastim in Neoadjuvant Treatment of Potentially Resectable BTC
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Neoplasms
Interventions: DRUG: Total Neoadjuvant Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voclosporin in Adolescents With Lupus Nephritis
Status: RECRUITING
Conditions: Adolescent Lupus Nephritis
Interventions: DRUG: Voclosporin|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interference Between Surgical Magnetic Drapes and Pacemakers
Status: COMPLETED
Conditions: Electromagnetic Interference
Interventions: DEVICE: Prototype surgical magnetic drape|DEVICE: Green Covidien Magnetic Drape|DEVICE: Jac-Cell Medic Reusable Magnetic Pad|DEVICE: DeRoyal Magnetic Pad size 20" x 16"|DEVICE: DeRoyal Magnetic Pad size 10" x 16"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: chemotherapy|PROCEDURE: conventional surgery|PROCEDURE: magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trail of Acupuncture and Liu-Zi-Jue Exercise for Dysphagia in Post-stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: acupuncture|COMBINATION_PRODUCT: Liu-Zi-Jue Gongfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotic Intake on Adiposity, Satiety and Gut Microbiota in Overweight and Obese Children
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Prebiotic fiber|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Young People's Health Assessment as Treatment and Health Guide
Status: COMPLETED
Conditions: Adolescent Behavior|Substance Use
Interventions: OTHER: Substance use questionnaire|OTHER: Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CIS
Status: COMPLETED
Conditions: Optic Neuritis|Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: OTHER: Gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Echocardiography to Prognostic Evaluation of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Echocardiography|OTHER: Hemodynamic examinations (right cardiac catheterization)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identifying Biomarkers and Changes in Cerebrospinal Fluid Collected Pre and Post Spinal Cord Stimulation in Subjects Suffering From Chronic Refractory Pain Conditions
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: PROCEDURE: Lumbar Puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Fatty Acid Supplementation on Substance Dependent Individuals
Status: COMPLETED
Conditions: Substance-related Disorders
Interventions: DRUG: Pro-eicosapentaenoic acid (EPA)|DRUG: Pro-docosapentaenoic acid (DPA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: NMDA Modulation in Antidepressant Nonresponders With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: NMDAE|DRUG: Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir (TFV) IVR|DRUG: Placebo IVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Nurse Process on Bowel Cleansing
Status: COMPLETED
Conditions: Colorectal Cancer|Colonoscopy Preparation|Boston Bowel Preparation Scale|Nursing
Interventions: BEHAVIORAL: Nursing Process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunotherapy Using Autologous T Cell-Engineered With CD19-specific Chimeric Antigen Receptor for the Treatment of Recurrent /Refractory B Cell Leukemia
Status: UNKNOWN
Conditions: Recurrent B-Cell Tumor|Refractory B-Cell Tumor
Interventions: BIOLOGICAL: CD19-specific chimeric antigen receptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bladder Dissection Before and After Uterine Incision in Cesarean Section for Morbidly Adherent Placenta
Status: UNKNOWN
Conditions: Morbidly Adherent Placenta
Interventions: PROCEDURE: bladder dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Carcinoma|P53 Mutation|Serous Carcinoma
Interventions: RADIATION: External Beam Radiation|DRUG: Niraparib|RADIATION: Vaginal high-dose rate brachytherapy|OTHER: Observation - no drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cyanoacrylate Tissue Adhesive With Suture in the Treatment of Gingival Recession
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: DEVICE: Use of periacryl in gingival recession closure procedures|PROCEDURE: Use of sutures in gingival recession closure procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Biomarker Enrichment and Treatment Selection
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Adavosertib|DRUG: Savolitinib|DRUG: Darolutamide|DRUG: CFI-400945|DRUG: Ipatasertib|DRUG: Durvalumab and Tremelimumab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excellence in Peripheral Arterial Disease Treatment of Superficial Femoral Artery Disease With Drug-eluting Stents
Status: TERMINATED
Conditions: Peripheral Vascular Diseases|Chronic Total Occlusion of Artery of the Extremities
Interventions: DEVICE: Drug-eluting stent|DEVICE: Bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Azithromycin Plus Doxycycline Versus Doxycycline Plus Placebo in Patients With Rocky Mountain Spotted Fever
Status: RECRUITING
Conditions: Rocky Mountain Spotted Fever
Interventions: DRUG: Azithromycin + Doxycycline|DRUG: Placebo + Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma
Status: COMPLETED
Conditions: Brain Cancer
Interventions: DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Mantle Cell Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Palbociclib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS for Cognitive Impairment Associated With Recent-onset Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Psychotic Disorder
Interventions: DEVICE: left fronto-temporal transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BACE Trial Substudy 2 - FarmEc Substudy
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Cancer Disparities for American Indians in the Rural Intermountain West
Status: COMPLETED
Conditions: Prostate Cancer|Colorectal Cancer|Breast Cancer|Cervical Cancer|Lung Cancer
Interventions: BEHAVIORAL: Navigation Services|BEHAVIORAL: Cancer education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Role of Ultrasound in Diagnosis of Muscle Diseases
Status: RECRUITING
Conditions: Ultrasound|Muscle Disease
Interventions: DEVICE: Neuromuscular Ultrasound (US)|DEVICE: Electrophysiological studies|DIAGNOSTIC_TEST: Seum CPK, CK-MM levels, Lactate dehydrogenase and alanine aminotransferase.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPB
Status: COMPLETED
Conditions: Nosocomial Pneumonia
Interventions: DRUG: Sham treatment|DRUG: 200- ppm NO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigations on the Effect of Kale on the Lipid Status
Status: UNKNOWN
Conditions: Effects of Kale Ingredients on Lipid Status Parameter
Interventions: DIETARY_SUPPLEMENT: Kale Preparation "Kale Powder"|DIETARY_SUPPLEMENT: Kale Preparation "Kale Extract"|DIETARY_SUPPLEMENT: Kale Preparation "Flavonoid Extract"|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Turkish Validity and Reliability of the Visual Function Classification System (VFCS)
Status: COMPLETED
Conditions: Cerebral Palsy|Visual Impairment|Visual Disorder|Cerebral Visual Impairment|Cerebral Palsy, Spastic
Interventions: OTHER: Observational questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath
Status: RECRUITING
Conditions: Pulmonary Nodules, Multiple|Pulmonary Nodules, Solitary|Lung Cancer
Interventions: OTHER: Gas chromatography-mass spectrometry(GC-MS) and micro Gas Chromatography-photoionisation detector (μGC-PID) system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: H-Senses Project - Self Care Mediated by the Senses
Status: COMPLETED
Conditions: Stress
Interventions: OTHER: one-sensory self care (Todo Dia®)|OTHER: multisensory self care (Todo Dia®)|OTHER: bi-sensory self care (Todo Dia®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal Cerebral Arteriopathy Steroid Trial
Status: ENROLLING_BY_INVITATION
Conditions: Pediatric Stroke|Arteriopathy|Arterial Ischemic Stroke
Interventions: DRUG: methylprednisolone, prednisolone, prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients
Status: COMPLETED
Conditions: Opioid Use|Opioid-Related Disorders|Opioid Abuse|Prescription Drug Abuse and Dependency
Interventions: OTHER: Default Prescribing Change
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lumbar Epidural Analgesia Versus Local Anesthesia With Dexmedetomidine Infusion in Endoscopic Lumbar Discectomy
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Dexmedetomidine Hydrochloride 'Precedex' combined with|PROCEDURE: Lumbar epidural analgesia with Bupivacaine 0.25% 'Sunnypivacaine'|PROCEDURE: General anesthesia|DRUG: Local infiltration with Lidocaine HCL 1%'Debocaine'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Interplay Between Oxalate, Immunity and Infection
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: DIETARY_SUPPLEMENT: Low Oxalate Diet|DIETARY_SUPPLEMENT: High Oxalate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Etanercept and Methotrexate in Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Arthritis, Psoriatic
Interventions: DRUG: Etanercept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Models for Dissemination of Injury Prevention Information in the Pediatric Emergency Department Setting
Status: WITHDRAWN
Conditions: Car Seats|Injuries
Interventions: BEHAVIORAL: Enhanced Standard Care (ESC)|BEHAVIORAL: Brief Motivational Intervention (BMI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sevoflurane-Remifentanil Anaesthesia. The Risk of Post Operative Nausea
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: PROCEDURE: Sevoflurane-remifentanil anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Patient Satisfaction and Dimensional Accuracy of Bre Flex and Peek for Removable Partial Dentures
Status: UNKNOWN
Conditions: Patient Satisfaction
Interventions: OTHER: PEEK|OTHER: Bre.flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of GS-9901 in Adults With Relapsed or Refractory Follicular Lymphoma, Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: GS-9901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab, Cisplatin, and Radiotherapy in Women With Locally Advanced Cervical Carcinoma
Status: UNKNOWN
Conditions: Cancer of the Cervix
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma-Secretase Inhibitor RO4929097 in Treating Patients With Metastatic or Unresectable Solid Malignancies
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacogenomic studies|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Status: UNKNOWN
Conditions: Anxiety Disorders|Oral Disease|Periodontal Diseases|Periodontal Attachment Loss|Periodontal Pocket|Periodontal Inflammation|Gingival Recession|Gingival Bleeding|Gingival Diseases|Bruxism|Caries,Dental|Health Care Seeking Behavior|Health Care Utilization|Self-Perception
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Vagus stimulation 1|PROCEDURE: Vagus stimulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19
Status: COMPLETED
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Respiration, Artificial
Interventions: DIAGNOSTIC_TEST: Arterial blood gas (ABG)|OTHER: Recording of hemodynamic monitoring|OTHER: Recording of respiratory monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Evaluating the Viability of L. Casei + Fish Oil Capsules
Status: UNKNOWN
Conditions: Signs and Symptoms, Digestive
Interventions: DIETARY_SUPPLEMENT: probiotic plus fish oil capsule|DIETARY_SUPPLEMENT: Fish oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Back Pain|Pain|Signs and Symptoms|Neuromuscular Manifestations
Interventions: BEHAVIORAL: Cognitive Functional Therapy|OTHER: Core Training Exercise and Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dancing on Cardiovascular and Functional Risk Factors in Older Women.
Status: UNKNOWN
Conditions: Aging|Cardiovascular Risk Factor|Physical Activity
Interventions: OTHER: Dance|OTHER: Walking|OTHER: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With One Suprachoroidal Stent
Status: COMPLETED
Conditions: Subject With Primary Open-angle Glaucoma (POAG)
Interventions: DEVICE: iStent Supra Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT)
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic|Stroke, Acute
Interventions: OTHER: Simplified imaging strategy|OTHER: Standard imaging strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Brain Metastases, Adult
Interventions: DRUG: Patritumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Moderate to Severe Plaque Psoriasis With Involvement of the Scalp
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: efalizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Massage for Itching Management in Liver Diseases
Status: COMPLETED
Conditions: Aromatherapy|Massage|Liver Diseases|Itching|pH Level|Skin Moisture
Interventions: OTHER: aromatherapy massage (diluted tea tree oil)|OTHER: aromatherapy massage (sweet almond oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib and Interferon Alfa in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: sorafenib tosylate|BIOLOGICAL: recombinant interferon alfa-2b|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Effectiveness, and Patient Experience of Online Acceptance and Commitment Therapy Plus Exercises for Older People With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: back exercise|BEHAVIORAL: back care education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study for Using Radiosurgery on Limited Metastases of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer, Metastatic
Interventions: PROCEDURE: Hypofractionated Stereotactic Body Radiation Therapy|RADIATION: Hypofractionated Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doppler-based Renal Resistive Index in Assessing Renal Dysfunction Reversibility in ICU Patients
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: OTHER: Doppler-based renal|BIOLOGICAL: blood sample and urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fetal Cell Receptors Repertoire
Status: RECRUITING
Conditions: Venous Ulcer|Sickle Cell Ulcer|Diabetic Ulcer|Post-partum Women|Mixed Ulcer
Interventions: OTHER: Saliva sampling|OTHER: Blood sampling|OTHER: Interviews|OTHER: Clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberous Sclerosis Complex
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Omega-3 Fatty Acids on Aspirin Resistance
Status: COMPLETED
Conditions: Increased Drug Resistance
Interventions: DRUG: Aspirin|DRUG: Lovaza|DRUG: Both Aspirin and Lovaza|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of CNTO 148 Subcutaneous Injection Compared With Placebo in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Golimumab|DRUG: MTX|DRUG: Placebo|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combinations of Cemiplimab (Anti-PD-1 Antibody) and Platinum-based Doublet Chemotherapy in Patients With Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: REGN2810|DRUG: REGN2810/chemo/ipi|OTHER: Chemotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Program Using Video Games Associated With Conventional Physiotherapy in Physical Functioning in Frail Elderly Compared to Conventional Physiotherapy
Status: UNKNOWN
Conditions: Frail Elderly
Interventions: OTHER: Exergames and conventional physiotherapy|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prenatal Ultrasound Screening of Intestinal Malrotation With a Higher Risk of Volvulus
Status: COMPLETED
Conditions: Intestinal Malrotation
Interventions: OTHER: MRI between 30-35 GA|OTHER: Pediatric surgeon meeting|OTHER: Postnatal abdominal ultrasound, barium enema and upper gastrointestinal|OTHER: +/- prophylactic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Non-surgical Periodontal Therapy in Patients Indicated for Bariatric Surgery
Status: COMPLETED
Conditions: Periodontitis|Obesity, Morbid|Bariatric Surgery Candidate
Interventions: PROCEDURE: Scaling and root planing|DEVICE: Probiotic lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Second Study of NicVAX/Placebo as an Aid for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BIOLOGICAL: NicVAX Vaccine|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: nCaF2 primer|DRUG: Control primer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality for the Mitigation of Anxiety During Intrathecal Administration in Participants With Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy (SMA)
Interventions: DEVICE: Virtual reality|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study)
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: raspberry powder, milled flaxseed and soy milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Prediction of Esophageal Varices in Patients With Non-Alcoholic Fatty Liver Disease With Advanced Fibrosis
Status: COMPLETED
Conditions: Esophageal Varices|Non-alcoholic Fatty Liver|Compensated Cirrhosis
Interventions: OTHER: Reviewing records retrospectively of patients undergoing screening endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesia for Endometrial Scratching
Status: COMPLETED
Conditions: Subfertility|Infertility
Interventions: DRUG: Ibuprofen 600 mg|DRUG: Lorazepam 1 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Soy Protein and Polydextrose on Food Intake in Young Chinese Adult Males
Status: COMPLETED
Conditions: Obesity|Satiety|Diabetes
Interventions: OTHER: Soy Protein|OTHER: Polydextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Fruquintinib in the Cross-line Treatment of Refractory mCRC
Status: RECRUITING
Conditions: Fruquintinib|Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib+PD-1 inhibitors|DRUG: Fruquintinib+TAS-102
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Acupuncture on Perceived Stress and Health in Military Service Members
Status: NOT_YET_RECRUITING
Conditions: Perceived Stress
Interventions: PROCEDURE: Manual Standardized Stress Acupuncture (MSSA)|BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerating TMS for Cervical Dystonia
Status: NOT_YET_RECRUITING
Conditions: Isolated Cervical Dystonia
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Versus Escalating Shocks in Cardioverting Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Standard escalating shocks|DEVICE: High energy shock protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AK112 Plus Platinum-based Chemotherapy for EGFR/ALK/ROS1 Positve NSCLC
Status: NOT_YET_RECRUITING
Conditions: Efficacy
Interventions: DRUG: PD-1/VEGR bispecific antibodies (AK112) plus Platinum-based Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS
Status: UNKNOWN
Conditions: Pain, Chronic|Urge Incontinence|Overactive Bladder Syndrome|Quality of Life
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroregeneration Enhanced by Transcranial Direct Current Stimulation (TDCS) in Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: DC-Stimulator to apply tDCS|DEVICE: DC-Stimulator to apply Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety of a Fixed Dose Combination of Fimasartan/Amlodipine/Rosuvastatin
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Fimasartan/Amlodipine/Rosuvastatin|DRUG: Fimasartan/Amlodipine|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM Patients
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exendin-4 Fc fusion protein injection|DRUG: Exendin-4 Fc fusion protein injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormone Replacement and Neural Cardiovascular Control in Postmenopausal Women
Status: TERMINATED
Conditions: Menopause|Aging|Blood Pressure
Interventions: DRUG: Transdermal estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 2
Status: COMPLETED
Conditions: Influenza|Respiratory Tract Infections
Interventions: BEHAVIORAL: Portal Reminders for Influenza Vaccination: Gain-framed|BEHAVIORAL: Portal Reminders for Influenza Vaccination: Loss-framed|BEHAVIORAL: Pre-commitment prompt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intra Dialytic Parenteral Nutrition and Nutritional Gap Nutritional Gap Identified by Indirect Calorimetry
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Protein Energy Wasting
Interventions: DEVICE: Indirect Calorimetry|DEVICE: Bio-electrical Impedance Analysis (BIA)|OTHER: Nutritional assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: tACS to Enhance Language Abilities
Status: RECRUITING
Conditions: Stroke|Aphasia, Acquired|Aphasia
Interventions: DEVICE: Active transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine
Status: TERMINATED
Conditions: Pain|Neoplasm|Cancer
Interventions: DRUG: Tapentadol in the Titration Phase|DRUG: Morphine in the Maintenance Phase|DRUG: Matching Placebo in the Maintenance Phase after Tapentadol in the Titration Phase|DRUG: Tapentadol in the Maintenance Phase|DRUG: Morphine in the Titration Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication for Gastric Cancer Prevention in the General Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Helicobacter Pylori Infection
Interventions: DRUG: 10-day bismuth-based quadruple therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Neurophysiological Facilitation Techniques on Health Parameters in Early Stages After Open Heart Surgery
Status: RECRUITING
Conditions: Open Heart Surgery|Cardiovascular Disease|Physiotherapy
Interventions: PROCEDURE: Phase 1 cardiac rehabilitation|PROCEDURE: Neurophysiological facilitation techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Use of Ureteral Access Sheath on Levels of Netrin-1 in Patients Undergoing RIRS
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: DEVICE: RIRS with UAS|DEVICE: RIRS without UAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test V930/V932 in Patients With Cancers Expressing Human Epidermal Growth Factor Receptor 2 (HER-2) and/or Carcinoembryonic Antigen (CEA)(V930-003)(COMPLETED)
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: V930|BIOLOGICAL: V932
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Biodistribution Study for Topically Applied ESBA105
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Pilot Study Using Anakinra/Kineret for the Treatment of Patients With Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Anakinra|Kineret|Atopic Dermatitis|Eczema|Allergic Disease
Interventions: DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Cleft Hard- and Soft Tissue Reconstruction With an Autogenous Tooth Derived Particulate Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: Cleft Lip and Palate
Interventions: PROCEDURE: Autogenous tooth derived particulate graft and a novel split thickness papilla curtain flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Fluid Immersion Simulation System|DEVICE: Air Fluidized Bed System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain With Differing Insufflation Pressures During Laparoscopic Hysterectomy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Lower Insufflation Pressure|PROCEDURE: Standard Insufflation Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Excretion Balance, Pharmacokinetics, and Metabolism Following of [14C]-Venglustat Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Disorders of Sphingolipid Metabolism|Healthy Volunteers
Interventions: DRUG: venglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Study of Laparoscopic-assisted Percutaneous Catheter-directed Drainage to Treat Early Severe Acute Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute Necrotizing
Interventions: PROCEDURE: laparoscopic-assisted percutaneous catheter drainage|DRUG: 0.5% 5-fluorouracil normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Fat Injection And Platelet Rich Plasma In Post Burn Facial Scar
Status: UNKNOWN
Conditions: Burn Scar
Interventions: PROCEDURE: platelet rich plasma injection in post burn facial scar|PROCEDURE: fat injection in post burn facial scar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Drug Use-results Survey on PROPESS Vaginal Inserts in Treatment for Initiation of Cervical Ripening in Patients at Term (From 37 Completed Weeks of Gestation)
Status: COMPLETED
Conditions: Cervical Ripening|Pregnancy
Interventions: OTHER: PROPESS Cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Manual Glide Path Establishment on Endodontic Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Manual glide path|PROCEDURE: Mechanical glide path
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Ruxolitinib 1.5% for Hidradenitis Suppurativa Treatment
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Ruxolitinib 1.5% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Continuous Versus Fixed Duration Therapy With Daratumumab, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma in Relapse
Interventions: COMBINATION_PRODUCT: Daratumumab/Lenalidomide/Dexamethasone for 24 months|COMBINATION_PRODUCT: Daratumumab/Lenalidomide/Dexamethasone until progression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52 Antibody) Therapy in Newly Diagnosed Subjects With Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: New Onset Type 1 Diabetes Mellitus
Interventions: DRUG: Campath 1H® (Alemtuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
Status: NOT_YET_RECRUITING
Conditions: Laparotomy|Dehiscence Wound|Surgical Site Infections|Trauma Abdomen|Emergency General Surgery
Interventions: DEVICE: triclosan-coated barbed suture|DEVICE: triclosan-coated non-barbed suture|DEVICE: Non-coated non-barbed suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Hyperimmune Convalescent Plasma in Moderate and Severe COVID-19 Disease
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-19 convalescent hyperimmune plasma|BIOLOGICAL: Non-convalescent fresh frozen plasma (Standard plasma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial on Comparison of Effectiveness and Safeness of Different Amifostine Regimens
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms|Salivary Gland Diseases|Bone Marrow Diseases|Mucositis
Interventions: DRUG: Amifostine every-other-day regimen|DRUG: Amifostine everyday regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: everolimus|DRUG: carboplatin|DRUG: pegylated liposomal doxorubicin hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Lowering Ability and Safety of an Olmesartan and Amlodipine Based Treatment Regimen in Patients With Stage I and Stage II Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine|DRUG: Olmesartan medoxomil plus amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopically-guided Epidural Block in the Midthoracic Region: A Comparison of Anterioposterior Versus Oblique View Approach
Status: TERMINATED
Conditions: Low Back Pain Requiring Epidural Injection
Interventions: PROCEDURE: oblique view approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER