pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Levosimendan Versus Placebo Before Tricuspid Valve Surgery in Patients With Right Ventricular Dysfunction
Status: RECRUITING
Conditions: Patients Referred for an Isolated or a Combined Surgical Correction of Functional Moderate to Severe Tricuspid
Interventions: DRUG: Levosimendan|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Clamping: What Are the Benefits
Status: COMPLETED
Conditions: Delayed Cord Clamping
Interventions: PROCEDURE: Delayed umbilical cord clamping|PROCEDURE: Immediate umbilical cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Cetirizine HCl 10 mg Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetirizine Hydrochloride 10 mg tablets, single dose|DRUG: Zyrtec® 10 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Nutrition Education Interventions for Adolescents
Status: RECRUITING
Conditions: Nutrition, Healthy|Nutrition Disorders in Adolescence|Eating Habit|Eating Behavior|Body Image
Interventions: BEHAVIORAL: Nutrition Education|BEHAVIORAL: nutritional status, eating habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Tolerability of Nerispirdine in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Nerispirdine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects
Status: COMPLETED
Conditions: Impaired Hepatic Function
Interventions: DRUG: eravacycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Solid Tumor|Recurrent Ewing Sarcoma|Recurrent Hepatoblastoma|Recurrent Malignant Germ Cell Tumor|Recurrent Malignant Solid Neoplasm|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Peripheral Primitive Neuroectodermal Tumor|Recurrent Rhabdoid Tumor|Recurrent Rhabdomyosarcoma|Recurrent Soft Tissue Sarcoma|Recurrent Wilms Tumor|Refractory Ewing Sarcoma|Refractory Hepatoblastoma|Refractory Malignant Germ Cell Tumor|Refractory Malignant Solid Neoplasm|Refractory Neuroblastoma|Refractory Osteosarcoma|Refractory Peripheral Primitive Neuroectodermal Tumor|Refractory Rhabdoid Tumor|Refractory Rhabdomyosarcoma|Refractory Soft Tissue Sarcoma
Interventions: DRUG: Onivyde|DRUG: Talazoparib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship of Hemoglobin A1c and Diabetic Wound Healing
Status: TERMINATED
Conditions: Diabetes, Type 1|Diabetes, Type 2|Foot Ulcer, Diabetic
Interventions: DRUG: Bacitracin|DRUG: AmeriGel®|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium
Status: COMPLETED
Conditions: Post-operative Delirium
Interventions: DRUG: L-tryptophan supplementation|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Circulating Tumor DNA in Patients at High Risk for Lung Cancer
Status: TERMINATED
Conditions: Cancer of the Lung|Lung Cancer|Lung Neoplasms|Adenocarcinoma of the Lung|Non Small Cell Carcinoma of the Lung|Small Cell Carcinoma of the Lung
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CB-839 in Combination With Niraparib in Platinum Resistant BRCA -Wild-type Ovarian Cancer Patients
Status: TERMINATED
Conditions: Ovarian Cancer|Resistant BRCA Wild-Type Ovarian Cancer
Interventions: DRUG: Cohort 1: Dose Escalation|DRUG: Cohort 2: Dose Escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collaborative H1N1 Adjuvant Treatment (CHAT) Pilot Trial
Status: TERMINATED
Conditions: H1N1 Influenza
Interventions: DRUG: Rosuvastatin or identical placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol Compared With Ketorolac for Post-operative Analgetic
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Paracetamol|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Stereotactic Radiosurgery|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: sFOLFOXIRI in Advanced Gastroesophageal Cancer, (SAGE)
Status: RECRUITING
Conditions: Gastro-Intestinal Cancer
Interventions: DRUG: Four week alternating FOLFOX and FOLFIRI (sFOLFOXIRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Music the Food of Anesthesia in Children?
Status: COMPLETED
Conditions: Music
Interventions: DEVICE: CD player|DEVICE: CEL-480 Sound Level Meter Sonometre|DEVICE: Earplug|PROCEDURE: Ambient operating room noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Immunogenicity, and Relative Efficacy of H1N1 Vaccines in Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK2340274A|BIOLOGICAL: GSK2340273A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Whole Body Vibration Training for Diabetic Patients With Burn Injury
Status: COMPLETED
Conditions: Burn Injury
Interventions: OTHER: whole body viberation|OTHER: Traditional program(balance exercises and resisted exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Pelubiprofen Tab. & Celebrex Cap. in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Pelubiprofen|Celebrex|Rheumatoid Arthritis
Interventions: DRUG: Pelubiprofen 30 mg|DRUG: Celebrex 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minirin Versus Oxybutynin for Nocturnal Enuresis in Children
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DRUG: Minirin|DRUG: Oxybutynin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Platelet-rich Plasma (PRP) and Low-intensity Extracorporeal Shockwave Therapy (Li-ESWT) on Erectile Dysfunction (ED)
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: COMBINATION_PRODUCT: autologous platelet-rich plasma and low-intensity extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Multiple Oral Doses of JNJ-42847922 on the Steady-state Pharmacokinetics of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Healthy Female Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ethinyl Estradiol + Levonorgestrel|DRUG: JNJ-42847922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Additional Effects of Steroid and Dextrose to Hyaluronic Acid on Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: compare the effects of steroid plus hyaluronic acid and destrose plus hyaluronic acid on knee osteroarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: FCR and Ibrutinib|DRUG: BR and Ibrutinib|DRUG: Ibrutinib and Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Doses of MRC375 in Moderate to Severe Rheumatoid Arthritis Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRC375|DRUG: Matching Placebo|DRUG: MRC375 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vitreoretinal Molecular Changes During Rhegmatogenous Retinal Detachment
Status: RECRUITING
Conditions: Rhegmatogenous Retinal Detachments
Interventions: BIOLOGICAL: Blood sampling|OTHER: vitreous sampling|OTHER: Sub-retinal fluid sampling|OTHER: Retinal tissue sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Pulmonary Hypertension Secondary|Heart Failure
Interventions: DRUG: Sodium Nitrite|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training in Patients With Persistent or Permanent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: standard care + moderate-intensity continuous exercise training|BEHAVIORAL: standard care + high-intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Cutaneous Neurofibromas
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery
Status: COMPLETED
Conditions: Hemostasis
Interventions: BIOLOGICAL: Human thrombin|BIOLOGICAL: Bovine thrombin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Diaper Change Position on Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: PROCEDURE: Control (Extended leg position) Group|PROCEDURE: Experimental (Legs are flexed toward abdomen) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Male and Female Japanese Volunteers
Interventions: DRUG: NXL104|DRUG: CAZ104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sleeve Gastrectomy Versus Medical Management for Remission of Diabetes in Mild to Moderately Obese Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|BEHAVIORAL: Intensive medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From Encapsulated Iron Sulphate in Microspheres
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: free FeSO4|DIETARY_SUPPLEMENT: free FeSO4 and empty microspheres|DIETARY_SUPPLEMENT: free FeSO4 and hylauronic acid|DIETARY_SUPPLEMENT: free FeSO4 and eudragit polymer|DIETARY_SUPPLEMENT: encapsulated FeSO4 3.2%|DIETARY_SUPPLEMENT: encapsulated FeSO4 20%|DIETARY_SUPPLEMENT: encapsulated FeSO4 3.2%, encapsulated Vitamin A|DIETARY_SUPPLEMENT: encapsulated FeSO4 3.2%, encapsulated Vitamin A, free Folic Acid|DIETARY_SUPPLEMENT: FeSO4 embedded in Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Different Solutions for Peristomal Skin Care in Patients With Pediatric Stoma
Status: NOT_YET_RECRUITING
Conditions: Colostomy Site
Interventions: OTHER: CLEANING SOLUTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Flow Nasal Oxygenation vs Endotracheal Intubation on Recovery Profiles in Laryngeal Microsurgery
Status: RECRUITING
Conditions: Cough
Interventions: DEVICE: HFNO group|DEVICE: ET group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer With Asymptomatic Untreated Brain Metastasis
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: carboplatin|DRUG: erlotinib [Tarceva]|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of EP-104IAR in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: EP-104IAR 25 mg|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMD 640 744 in Montanide ISA 51 VG Administered in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: EMD 640744|BIOLOGICAL: EMD 640744|BIOLOGICAL: EMD 640744|OTHER: Montanide ISA 51 VG|OTHER: Montanide ISA 51 VG|OTHER: Montanide ISA 51 VG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure and Ocular Perfusion Pressure of Cosopt in Normal Tension Glaucoma
Status: COMPLETED
Conditions: Normal Tension Glaucoma
Interventions: DRUG: dorzolamide/timolol|DRUG: latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short vs Long Dental Implants for the Fixed Rehabilitation of the Fully Edentulous Mandible
Status: UNKNOWN
Conditions: Edentulous Jaw
Interventions: DEVICE: ASTRA TECH Implant System, OsseoSpeed™ 4.0 S, length: 6 mm|DEVICE: ASTRA TECH Implant System, OsseoSpeed™ 4.0 S, length: ≥11mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel Study
Status: COMPLETED
Conditions: Open-angle Glaucoma, Ocular Hypertension
Interventions: DRUG: Vehicle of DE-126 Ophthalmic Solution, high dose of DE-126 Ophthalmic Solution|DRUG: Topical ultra-low dose of DE-126 Ophthalmic Solution|DRUG: Topical low dose of DE-126 Ophthalmic Solution|DRUG: Topical medium dose of DE-126 Ophthalmic Solution|DRUG: Topical high dose of DE-126 Ophthalmic Solution|DRUG: 0.005% Latanoprost Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: DNT cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes|Postprandial Oxidative Stress
Interventions: OTHER: Bagueutte Cheese Gourmet (Crocodille)|OTHER: Cous-cous sandwich|OTHER: McCountry sandwich (McDonald's)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhanced Recovery After Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiac Surgery|Coronary Artery Disease|Aortic Valve Disease|Mitral Valve Disease|Tricuspid Valve Disease|Aortic Root Dilatation
Interventions: DIETARY_SUPPLEMENT: Pre-operative Carbohydrate PreLoad drink|DRUG: Oral Gabapentin pre-op|DRUG: Oral Lansoprazole pre-op|DRUG: Intravenous Paracetamol intra-operatively|DRUG: Intravenous Dexamethasone intra-operatively|DRUG: Intravenous Ondansetron intra-operatively|DRUG: Infiltration of surgical wounds with local anaesthetic|DRUG: Intravenous Magnesium intra-operatively|DRUG: Post-operative Gabapentin analgesia|DRUG: Post-operative oral Paracetamol analgesia|DRUG: Post-operative Ondansetron anti-emesis|PROCEDURE: Early extubation|PROCEDURE: Early mobilisation/physiotherapy|OTHER: Encourage early oral food intake
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Diaphragmatic Stimulation in Critically Ill Elderly Patients
Status: UNKNOWN
Conditions: ICU Acquired Weakness|Diaphragmatic Injury
Interventions: DEVICE: Transcutaneous Electrical Diaphragmatic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Prostatitis
Interventions: DRUG: Alfuzosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Psychoeducational Intervention Model to Improve Nutritional Status in Low Resource Settings
Status: COMPLETED
Conditions: Child Malnutrition|Child Overnutrition|Malnutrition in Children|Malnutrition, Child|Nutrition Disorders, Child|Malnutrition
Interventions: BEHAVIORAL: Psychoeducational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SAMPAP Trial -Impact of a Novel Sleep Apnea Management Group Intervention on Positive Airway Pressure Adherence
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Apnea
Interventions: OTHER: SAM Clinic Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity
Status: COMPLETED
Conditions: Laparoscopic Abdominal Surgery
Interventions: DIETARY_SUPPLEMENT: simple carbohydrate drink|DIETARY_SUPPLEMENT: complex carbohydrate drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose, 2-Period, 2-Treatment, 2-Way Crossover Bioequivalency Study of Balsalazide Disodium 750 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Balsalazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial of Streamlined Genetic Education and Testing for Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer, Epithelial|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: BEHAVIORAL: Streamlined Education|BEHAVIORAL: Traditional Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnetic Seizure Therapy for Psychotic Disorders
Status: NOT_YET_RECRUITING
Conditions: Psychotic Disorders
Interventions: DEVICE: Magnetic seizure therapy by Magnetic stimulator|DRUG: Antipsychotic medications (such as olanzpine, risperidone, aripiprazole, quetiapine, amisulpride, etc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-Effectiveness of Cognitive Stimulation Therapy - Spain (CST-ES) in People Living With Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Neurocognitive Disorders|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive Stimulation Therapy (CST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open, Parallel, Controlled, Multi-center, Interventional, Cross-sectional Study to Evaluate the Detection Rate of Psoriatic Arthritis in Korean Moderate-to-severe Psoriasis Patients, With or Without Active Screening for Arthritis in Psoriasis (ASAP Study)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DIAGNOSTIC_TEST: Routine practice groups|DIAGNOSTIC_TEST: EARP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying the Performance of OCT C-scan in the Screening for Retinopathy Related to Synthetic Antimalarials
Status: COMPLETED
Conditions: Toxicity, Drug|Maculopathy
Interventions: DEVICE: spectral domain optical coherence tomography C-scan and multifocal electroretinogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Slenyto for Insomnia in Children With ASD
Status: WITHDRAWN
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Laryngeal Mask Airway and Endotracheal Tube in General Anesthesia for Premature Neonates
Status: COMPLETED
Conditions: Preterm Infant|Anesthesia|Respiratory Complication
Interventions: DEVICE: intubation with Endotracheal tube|DEVICE: intubation with laryngeal mask airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single and Repeated Doses of LY3556050 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3556050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexamethasone With or Without Oblimersen in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Botulinum Toxin Type A for Injection to Treat Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: Botulinum Toxin Type A|BIOLOGICAL: Active Comparator botulinum toxin|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease|Stable Angina|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Venous Thrombosis|Pulmonary Embolism|Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Standard of care drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Analgesia|Surgery|Renal Stone
Interventions: PROCEDURE: Continous Quadratum Lumborum Block III|PROCEDURE: Single dose Quadratum Lumborum Block III|PROCEDURE: Intra-venous Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital
Status: UNKNOWN
Conditions: Persistent Asthma
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Strategies to Improving Warfarin Adherence
Status: COMPLETED
Conditions: Atrial Fibrillation|Deep Venous Thrombosis|Dilated Cardiomyopathies
Interventions: BEHAVIORAL: Lottery arm (Lottery and Med-eMonitor)|BEHAVIORAL: Non-Lottery (Med-eMonitor only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Kefir Whey Postbiotics
Status: ENROLLING_BY_INVITATION
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Whey postbiotics derived from kefir lactic acid bacteria|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Nirmatrelvir|DRUG: Ritonavir|DRUG: Placebo for nirmatrelvir|DRUG: Placebo for ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: 0.24% Sodium Fluoride Dentifrice|DRUG: 1.5% Arginine Dentifrice|DRUG: 4.0% Arginine Dentifrice|DRUG: 8.0% Arginine Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regorafenib in Subjects With Antiangiogenic-naive and Chemotherapy-refractory Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Area of Ischemia in Patients With Subacute Stroke Via a Hybrid EEG-fNIRS Brain-computer Interface
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: Combined EEG and fNIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Ketogenic Diet in Overweight and Obese Women With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Female
Interventions: OTHER: Adequate and balanced healthy diet program (CHO: 45-60%, protein:10-20%, fat:20-35%)|OTHER: Ketogenic diet program (CHO: 6%, protein:19%, fat:75%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analyses of Interleukin-6, Presepsin and Pentraxin-3 in the Diagnosis and Severity of Late-onset Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: OTHER: interleukin-6, presepsin and pentraxin-3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mycophenolate Mofetil in Systemic Lupus Erythematosus (MISSILE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Atherosclerosis
Interventions: DRUG: Mycophenolate mofetil|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Thymic Carcinoma|Metastatic Thymic Carcinoma|Recurrent Thymic Carcinoma|Unresectable Thymic Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?
Status: UNKNOWN
Conditions: Kidney Failure, Chronic
Interventions: DRUG: vitamin C, intravenous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cetirizine Hydrochloride Tablets, 10 mg Bioequivalence Study of Dr.Reddy's Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetirizine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD)
Status: COMPLETED
Conditions: Cerebral Adrenoleukodystrophy (CALD)
Interventions: GENETIC: Lenti-D Drug Product (eli-cel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gold Factor on Knee Joint Health and Function
Status: COMPLETED
Conditions: Knee Arthritis|Knee Osteoarthritis|Knee Pain Chronic|Knee Discomfort|Rheumatoid Arthritis|Knee Pain Swelling
Interventions: DIETARY_SUPPLEMENT: Gold Factor (Gold Nanoparticles, AuNPs)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of RadiaAce Gel in the Prevention and Treatment of Radiation Dermatitis in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Radiation Dermatitis
Interventions: DEVICE: RadiaAce gel|DEVICE: Biafine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aveir DR i2i Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Pacemaker, Artificial|Cardiac Rhythm Disorder|Bradycardia
Interventions: DEVICE: Aveir DR Leadless Pacemaker System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Trial to Collect Safety Data and Sera for Immunogenicity Testing in Healthy Children Given Fluzone® Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 2007-2008 Influenza Virus Vaccine|BIOLOGICAL: 2007-2008 Influenza Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The APS Phenotyping Study
Status: RECRUITING
Conditions: ARDS|Sepsis|Pneumonia
Interventions: OTHER: Blood collection|OTHER: Urine Collection|OTHER: Nasal, oral, and rectal swabs|OTHER: Stool collection|OTHER: Heat Moisture Exchange Filter collection|OTHER: Tracheal Aspirate sample collection|PROCEDURE: Non-bronchoscopic bronchoalveolar lavage (NBBAL)|OTHER: Surveys|OTHER: Short physical performance battery|OTHER: Hand grip strength|OTHER: CNS Vital Signs|OTHER: Muscle Ultrasound|OTHER: Muscle Strength|OTHER: Spirometry|OTHER: Lung Diffusion Testing (DLCO)|RADIATION: Chest CT Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergy to Pollen|Rhinoconjunctivitis
Interventions: OTHER: Exposure to placebo|OTHER: Exposure to allergen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Glioblastoma Multiforme
Interventions: DRUG: Celecoxib|DRUG: Isotretinoin|DRUG: Temozolomide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Endometriosis: A Cohort Study
Status: COMPLETED
Conditions: Endometriosis Thoracic|Endometriosis of Lung|Endometriosis of Pleura|Endometriosis-related Pain|Endometriosis
Interventions: OTHER: Satisfaction of patients after medical and surgical treatment for thoracic endometriosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By Chemotherapy
Status: TERMINATED
Conditions: Nausea|Vomiting|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: Decadron®|DRUG: Benadryl®|DRUG: Ativan®|DRUG: ondansetron hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of AIDSVAX B/B and AIDSVAX B/E, Two Possible Vaccines
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1|BIOLOGICAL: MN rgp120/HIV-1 and A244 rgp120/HIV-1|BIOLOGICAL: Aluminum hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Closed Loop Pumps vs. Traditional Open Loop Pumps in Managing Blood Glucose Levels in T1DM Patients Fasting in Ramadan.
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Pump Therapy
Interventions: DEVICE: Advanced hybrid closed loop insulin pump|OTHER: Open Loop Insulin Delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Elliptical Training on Metabolic Homeostasis in Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: exercise training on elliptical device|BEHAVIORAL: group B (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM
Status: TERMINATED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: Daily injection of KBP/placebo for up to 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: Oxytocin|OTHER: Saline as a nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Palonosetron Hydrochloride Capsule Was Used to CINV
Status: RECRUITING
Conditions: Nausea and Vomiting
Interventions: DRUG: Palonosetron hydrochloride capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Ramelteon in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Ramelteon and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Vancomyin for Primary Clostridium Difficile Infection Prophylaxis in Patients Receiving High-Risk Antibiotics
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Prophylaxis|Vancomycin
Interventions: DRUG: Vancomycin Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interest of Flow Cytometry for the Diagnosis, the Follow up and Specific Immunotherapy (SIT) Arrest of Hymenoptera Venom Allergy
Status: COMPLETED
Conditions: Allergy
Interventions: OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol plus hydrocortisone (LEO 80190)|DRUG: LEO 80190 Vehicle|DRUG: Hydrocortisone|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Hepatic Encephalopathy|Hepatitis C|Liver Cirrhosis
Interventions: DRUG: Rifaximin (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Different Hormone Doses in 2019-nCoV Severe Pneumonia
Status: UNKNOWN
Conditions: 2019-nCoV Severe Pneumonia
Interventions: DRUG: Methylprednisolone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Fluoroquinolone in Staphylococcus Aureus Bacteremia
Status: COMPLETED
Conditions: Staphylococcus Aureus|Bacteremia|Endocarditis|Sepsis
Interventions: DRUG: trovafloxacin and levofloxacin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emergency Department Healthcare Education Assessment and Response for Teen Relationships: A Pilot Feasibility Study
Status: COMPLETED
Conditions: Adolescent Behavior|Emergency Department|Abuse Physical|Abuse Mental|Abuse Verbal|Abuse Domestic|HEART|Intimate Partner Violence
Interventions: BEHAVIORAL: ED-HEART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computer-assisted Instruction Before Colonoscopy is as Effective as Nurse Counselling, a Controlled Trial
Status: COMPLETED
Conditions: Colonoscopy|Education, Patient|eHealth
Interventions: OTHER: Computer Assisted Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Supporting Healthy Relationships Program for FRAMEWorks (SHR FRAMEWorks)
Status: RECRUITING
Conditions: Parenting|Family Relations|Relationship, Family
Interventions: BEHAVIORAL: Supporting Healthy Relationships program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to See Whether Breath-Hold Techniques During RT Are Effective in Helping to Improve Sparing of the Heart
Status: UNKNOWN
Conditions: Breast Cancer|Adverse Effect of Radiation Therapy
Interventions: RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Toripalimab Combined With Anlotinib in Unresectable Locally Advanced or Metastatic Acral Malignant Melanoma
Status: UNKNOWN
Conditions: Locally Advanced or Metastatic Acral Malignant Melanoma
Interventions: DRUG: Toripalimab and Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Look at How Semaglutide Affects Gastric Emptying in People With Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Genio System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study of Three Modular Devices for Aid in Patient Standing and Transfer
Status: COMPLETED
Conditions: Mobility Limitation
Interventions: DEVICE: Standing attempts with the "Vertic'Easy" Device|DEVICE: Standing attempts with the "Turner" Device|DEVICE: Standing attempts with the "Tina" device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury
Status: TERMINATED
Conditions: Tibial Meniscus Injuries|Tibial Meniscus Tears|Tibial Meniscus, Torn|Anterior Cruciate Ligament Tear
Interventions: DRUG: Zilretta|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Communication Intervention for Fecal Ostomy Surgery
Status: RECRUITING
Conditions: Surgery|Colostomy Stoma|Ileostomy - Stoma
Interventions: BEHAVIORAL: Communication Intervention for fecal ostomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fed Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg
Status: COMPLETED
Conditions: Healhty
Interventions: DRUG: Amlodipine and Benazepril HCl Capsules 10 mg/20 mg|DRUG: Lotrel® Capsules 10 mg/20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenail
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: EcoNail™ (econazole 5%/SEPA® 18% nail lacquer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT