pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Exercise on Cognitive Status in Older Adults
Status: COMPLETED
Conditions: Older People
Interventions: OTHER: Aerobic exercise training combined with lower limb strengthening|OTHER: Dual-task training combined with lower limb strengthening group (DG)|OTHER: Aerobic exercise training combined with dual-task training and lower limb strengthening|OTHER: Only lower limb strengthening group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Anesthesia in Operative, Awake, Office Hysteroscopy. A Randomized Double-blind Placebo-controlled Trial
Status: COMPLETED
Conditions: Anesthesia, Local|Office Hysteroscopy
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QA102 Phase 1 Study in Healthy Young and Older Adult Subjects
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: QA102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Prophylactic Tamsulosin for Postoperative Urinary Retention in Primary Total Hip and Knee Arthroplasty Patients
Status: TERMINATED
Conditions: Postoperative Urinary Retention
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Rivaroxaban for the Prevention of Stroke in Subjects With Non-Valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Warfarin|DRUG: Rivaroxaban placebo|DRUG: Warfarin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Single and Multiple-Dose Study of SB1578
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: SB1578|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Different CSII and CGM Systems on Different Clinical Outcome Variables in Children and Adolescents With Type 1 Diabetes. An Observational Study Form the Norwegian Childhood Diabetes Registry (NCDR)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: CSII and CGM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapy
Status: NOT_YET_RECRUITING
Conditions: Cancer|Prostate Cancer|Metastatic Cancer|Metastatic Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-I&T - escalating renal absorbed dose|DRUG: 177Lu-PSMA-I&T - recommended phase 2 regime
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Health-enabled Lifestyle Intervention Among Women With History of Gestational Diabetes(GDM)
Status: COMPLETED
Conditions: Healthy|Gestational Diabetes Mellitus in Pregnancy|Diabetes, Gestational
Interventions: BEHAVIORAL: Personalized mHealth intervention to promote short-term metabolic and mental health among women with a history of Gestational Diabetes Mellitus (GDM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Herbal Preparation and Glucose Homeostasis
Status: COMPLETED
Conditions: Glucose Tolerance|Lipid Homeostasis|Vascular Function|Inflammation
Interventions: DIETARY_SUPPLEMENT: herbal supplement|OTHER: placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Transitional Cell Carcinoma of Bladder|Urethra Cancer|Ureter Cancer|Malignant Tumor of Renal Pelvis
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|BIOLOGICAL: ALT-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Immunotherapy in Biochemically Recurrent Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: PROSTVAC-V|BIOLOGICAL: PROSTVAC-F|DRUG: MSB0011359C (M7824)|BIOLOGICAL: CV301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Versus Intravenous Chemotherapy for Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic
Interventions: PROCEDURE: Transcatheter arterial infusion|PROCEDURE: Intravenous chemotherapy|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab
Status: COMPLETED
Conditions: Previously Treated Metastatic Adenocarcinoma of the Pancreas
Interventions: BIOLOGICAL: CRS-207|BIOLOGICAL: CRS-207|DRUG: nivolumab|BIOLOGICAL: GVAX|DRUG: CY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Elderly|Surgery|Analgesia|Dexmedetomidine|Long-term Outcome
Interventions: DRUG: Dexmedetomidine supplemented morphine analgesia|DRUG: Morphine analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers
Status: COMPLETED
Conditions: Sarcoma|Thoracic Cancer|Abdominal Cancer|Pelvic Cancer
Interventions: RADIATION: Stereotactic body radiotherapy|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Velpatasvir Fixed Dose Combination in Participants With Chronic Hepatitis C Virus Infection Who Have Received a Liver Transplant
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Epratuzumab in Systemic Lupus Erythematosus (SLE)
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Esophageal Cancer and Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Personalized mRNA Tumor Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Salt and Water to Prevent Contrast Nephropathy
Status: WITHDRAWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Intravenous Saline|BIOLOGICAL: Oral Salt and Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Marketing Surveillance (All Case Surveillance) on Treatment With Alhemo® in Patients With Haemophilia A or Haemophilia B With Inhibitors
Status: ENROLLING_BY_INVITATION
Conditions: Haemophilia A|Haemophilia B
Interventions: DRUG: Concizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Steroid Injection Treatment of Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Methylprednisolone 40 mg|DRUG: Methylprednisolone 80 mg|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantable Vagus Nerve Stimulation Modulation of Coeruleus-Norepinephrine Network for Mild-Moderate AD Patients
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Vagus Nerve Stimulation Modulation of the Coeruleus-Norepinephrine Network
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lasers to Aid in Treatment of Acne Scars
Status: NOT_YET_RECRUITING
Conditions: Acne Scars
Interventions: DEVICE: Picosecond 755nm Alexandrite Laser|DEVICE: Picosecond 755nm Alexandrite Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Postural Tachycardia Syndrome|Orthostatic Intolerance|Sleep Disorders
Interventions: DEVICE: Actigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platelet Rich Plasma in Bleeding Peptic Ulcer
Status: UNKNOWN
Conditions: Bleeding Ulcer
Interventions: DRUG: PLATELET RICH PLASMA|DRUG: diluted epinephrine|DEVICE: hemoclips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of SB1518 for the Treatment of Advanced Lymphoid Malignancies
Status: COMPLETED
Conditions: Lymphoma, Malignant|Hodgkin's Lymphoma|B Cell Lymphoma
Interventions: DRUG: SB1518
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Breast Cancer|Pancreatic Cancer
Interventions: DRUG: Ibrutinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Phone Application Supported Nutrition Education on Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: This study is a randomized controlled study aiming to evaluate the effect of phone application supported nutrition education on weight loss according to standard education.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia
Status: UNKNOWN
Conditions: Gestational Trophoblastic Neoplasia
Interventions: DRUG: Methotrexate|PROCEDURE: hysteroscopic repeat curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Perirectal Fistula With Cutting Seton vs. Collagen Plug
Status: COMPLETED
Conditions: Anal Fistula
Interventions: PROCEDURE: Collagen Plug Placement|PROCEDURE: Seton placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Impact of Patent Ductus Arteriosus on Brain Function in Preterm Neonates: Multimodal Approach Integrating EEG-NIRS, Ultrasound and Clinical Data
Status: COMPLETED
Conditions: Ductus Arteriosus, Patent
Interventions: DEVICE: TFU-NIRS|DEVICE: NIRS|DEVICE: EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cladribine, Cytarabine, and Imatinib Mesylate in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Blastic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: cladribine|DRUG: cytarabine|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: EGEN-001 and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Undifferentiated Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: PEG-PEI-cholesterol Lipopolymer-encased IL-12 DNA Plasmid Vector GEN-1|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASSESSMENT OF CLINICAL PARAMETERS AND LASER DOPPLER FLOWMETRY FOR THE TREATMENT OF MULTIPLE GENGIVAL RECESSIONS WITH TWO TYPES OF SUBEPITELIAL CONNECTIVE GRAFT: RANDOMIZED CLINICAL STUDY
Status: UNKNOWN
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: Root coverage treatment with subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Locally Advanced Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: ZD 1839 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shifting Rehabilitation Paradigms in Skilled Nursing Facilities
Status: COMPLETED
Conditions: Physical Deconditioning
Interventions: OTHER: IntenSive Therapeutic Rehabilitation for Older Skilled Nursing Home Residents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azelaic Acid Versus Hydroquinone in Melasma
Status: UNKNOWN
Conditions: Melanosis
Interventions: DRUG: azelaic acid gel|DRUG: hydroquinone cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination
Status: COMPLETED
Conditions: Hepatitis A|Hepatitis B
Interventions: BIOLOGICAL: Twinrix|BIOLOGICAL: Engerix-B|BIOLOGICAL: Havrix|BIOLOGICAL: HBVAXPRO|BIOLOGICAL: Vaqta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison in Difficult Airway Scenario Induced in Patients With Laryngeal Mask Airway (LMA)-Classic™, LMA™ - Flexible and LMA - Proseal™
Status: COMPLETED
Conditions: Difficult Airway
Interventions: DEVICE: Laryngeal Mask Airway Classic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Formation of Health Professionals Through in Situ Simulation to Improve Performances During the Initial Step of Thrombectomy for Ischemic Strokes
Status: UNKNOWN
Conditions: Time|Benefit of in Situ Simulation for This Kind of Training|Installation of the Patient Until the Percutaneous
Interventions: OTHER: In situ simulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Pelvic Proprioceptive Neuromuscular Facilitation Techniques in Patients With Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: The Patient Education|OTHER: The Pelvic Proprioceptive Neuromuscular Facilitation Techniques Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Activity of Digoxin With Decitabine in Adult AML and MDS
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Decitabine|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Analgesy With Emla and/or Nitrous Oxide in Pediatric Patients for Lumbar Puncture
Status: COMPLETED
Conditions: Leukemia|Non Hodgkin Lymphoma
Interventions: DRUG: Livopan|DRUG: Livopan|DRUG: EMLA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
Status: WITHDRAWN
Conditions: Hypothyroidism
Interventions: DRUG: Iohexol|DRUG: Iodixanol|DRUG: Iopromide|DRUG: Ioversol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Virtual Human Delivered Nutrition Module for Colorectal Cancer Prevention
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: virtual technology - high interactive|OTHER: virtual technology - low interactive|OTHER: non-colorectal cancer related module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: TMHT - Difficult Intubation Prediction Using Videolaryngoscopy
Status: COMPLETED
Conditions: Predictive Value of Tests|Intubation
Interventions: PROCEDURE: Macintosh laryngoscopy|PROCEDURE: McGrath MAC video laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transanal Decompression Tube Versus Stent for Acute Malignant Left-sided Colonic and Rectal Obstruction
Status: TERMINATED
Conditions: Colonic Cancer|Rectal Cancer
Interventions: DEVICE: Transanal decompression tube|DEVICE: Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Self-management Program for Spinal Cord Injury: Feasibility Study of SCI&U
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: SCI&U online health coaching program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy And Safety Study Of Naftopidil to Patients Treatment With LUTS
Status: WITHDRAWN
Conditions: Hyperplasia
Interventions: DRUG: Naftopidil|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Myocardial Ischemia|Arteriosclerosis|Cardiovascular Diseases
Interventions: PROCEDURE: Fractional flow reserve-guided CABG|PROCEDURE: Angiography-guided CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Safety, Dose Finding & Antiviral Activity of RD-X19 in Mild/Moderate Outpatient COVID-19
Status: COMPLETED
Conditions: COVID19
Interventions: DEVICE: RD-X19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fermented Soybean (FSB) Supplementation on Gas-troesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastro Esophageal Reflux
Interventions: DIETARY_SUPPLEMENT: Fermented Soybean|DIETARY_SUPPLEMENT: Supplement without fermented soybean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of Sunitinib Malate In Chinese Patients With Imatinib Resistant Or Intolerant Malignant Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors
Interventions: DRUG: Sunitinib Malate (SU011248)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromyographic Estimation of Neuro-muscular Coordination of Masticatory Muscles in Patients Treated With Implants (D-2012-057)
Status: COMPLETED
Conditions: Edentulous|Teeth Replacement|Bounded Edentulous Space
Interventions: PROCEDURE: EMG befor denture treatment|PROCEDURE: EMG in a month after termination of treatment|PROCEDURE: EMG in a 3 months after termination of treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Response and Insulinaemic Response for Nutralys S85 Plus and Whey Protein
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 10 g NUTRALYS®S85 Plus pea protein|DIETARY_SUPPLEMENT: 20 g NUTRALYS®S85 Plus pea protein|DIETARY_SUPPLEMENT: 10 g Whey protein concentrate|DIETARY_SUPPLEMENT: 20 g Whey protein concentrate|DIETARY_SUPPLEMENT: 50 g Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Knee Osteoarthritis: Neuromuscular Electrical Stimulation and Low-level Laser.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Laser Therapy|OTHER: Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swiss SOS MoCA - DCI Study
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage|Delayed Cerebral Ischemia|Stroke|Complication|Cognitive Impairment|Cognitive Deficit|Cognitive Deterioration|Cognitive Deficits Following Cerebral Infarction
Interventions: OTHER: There is no intervention for this study. Patients are allocated to the study groups based on whether or not DCI occurs.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Performance of PSMA PET/CT for Pre-operative Lymph Node Assessment in Intermediate and High-risk Non-metastasic Prostate Cancer (PREOP-PSMA ).
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PSMA PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Taping Technique With Supervised Exercises Protocol on Pain and Functional Status in Individuals With Arthritis
Status: COMPLETED
Conditions: Patellofemoral Osteoarthritis
Interventions: OTHER: Taping technique|OTHER: A supervised exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, and Efficacy of GS-5718 in Participants With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-modifying Antirheumatic Drug(s) (bDMARDs) Treatment
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GS-5718|DRUG: GS-5718|DRUG: Placebo to match GS-5718|DRUG: Tofacitinib 5 mg|DRUG: Placebo to match Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases
Status: RECRUITING
Conditions: Colorectal Cancer Liver Metastases|Regorafenib
Interventions: DRUG: Regorafenib and DIBIRI|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Evaluation of the ICP Waveform Tracing Capabilities and Safety of HS-1000 Device
Status: COMPLETED
Conditions: Brain Injuries|Intracranial Hypertension
Interventions: DEVICE: HS-1000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cast OFF Trial: One Versus Four-five Weeks of Plaster Cast Immobilization
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: One week of plaster cast|PROCEDURE: Four-Five weeks of plaster cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of DTX301 AAV- Mediated Gene Transfer for Ornithine Transcarbamylase(OTC) Deficiency
Status: RECRUITING
Conditions: OTC Deficiency
Interventions: GENETIC: DTX301|OTHER: Placebo|DRUG: Oral Corticosteroids|DRUG: Placebo for oral corticosteroids|DRUG: Sodium Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of Oral Lithium in Patients With Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Lithium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of GW642444M Comparing Placebo In Adolescent And Adult Subjects With Persistent Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW642444M|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation for Reduction of Pain and Improvement of Insulin Sensitivity in Adult Polycystic Kidney Disease
Status: UNKNOWN
Conditions: Adult Polycystic Kidney Disease
Interventions: PROCEDURE: renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy
Status: COMPLETED
Conditions: HIV Prevention|Transgender Health
Interventions: DRUG: 200 mg emtricitabine and 300 mg tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Effects of Omega-3 Supplementation on Some Serum BDNF، Follistatin، Irisin Levels in Men With CAD
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Isotretinoin vs Ancomparison of Oral Isotretinoin vs Antibiotics on Corneal Thickness With AV
Status: ACTIVE_NOT_RECRUITING
Conditions: Cornea
Interventions: DIAGNOSTIC_TEST: Oral Isotretinoin|COMBINATION_PRODUCT: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rectal Microbicide Safety and Acceptability Trial of Topically Applied Tenofovir Compared With Oral Tablet
Status: COMPLETED
Conditions: HIV Prevention|HIV Infections
Interventions: DRUG: Tenofovir|DRUG: HEC Placebo|DRUG: Open label tenofovir tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in France During the COVID-19 Epidemic
Status: RECRUITING
Conditions: Postpartum Depression|Covid19|Prevalence|Social Distance
Interventions: OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Recurrent Glioblastoma Multiforme (GBM)
Interventions: DRUG: Imatinib tablets|DRUG: Hydroxyurea capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tetanus Immunization in Subjects With No Immunization History or With Tetanus Antibody Levels Below Protective Levels
Status: TERMINATED
Conditions: Tetanus
Interventions: DRUG: Tetanus Immune Globulin (Human)|BIOLOGICAL: Diphtheria-Tetanus Toxoids Adsorbed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Peripheral Stem Cell Transplantation Following Radiation Therapy in Treating Patients With Hodgkin's Disease or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Macronutrients and Heart Disease Risk
Status: COMPLETED
Conditions: Obesity|Body Composition|Blood Pressure|Cardiovascular Diseases
Interventions: BEHAVIORAL: low carbohydrate diet|BEHAVIORAL: low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxygen Atomizing Inhalation of EGCG in the Treatment Interstitial Pneumonia in Cancer Patients
Status: RECRUITING
Conditions: Interstitial Pneumonia|Neoplasms Malignant
Interventions: DRUG: EGCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efavirenz to Nevirapine Switch and Low-Density Lipoprotein (LDL)-Dyslipidemia
Status: COMPLETED
Conditions: HIV Infections|Hypercholesterolemia|Antiretroviral Therapy
Interventions: DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Women's Refusal to Participate in a Randomized Trial Involving First-trimester Screening for Pre-eclampsia: Factors Associated With Refusal and Reasons for Acceptance and Refusal
Status: RECRUITING
Conditions: Pregnancy Related
Interventions: BEHAVIORAL: Questionnaire|BEHAVIORAL: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrated Versus Standard Palliative Care in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Standard Palliative Care Group|OTHER: Integrated Palliative Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decompression Versus Heat and Decompression in Knee OA
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: standard physical therapy|OTHER: knee Decompression|OTHER: hot pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations
Status: RECRUITING
Conditions: Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: Amivantamab 1050mg|DRUG: Amivantamab 1400mg|DRUG: Amivantamab (to be determined)|DRUG: Amivantamab (to be determined)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vicryl Plus and Monocryl Plus in Breast Surgery
Status: COMPLETED
Conditions: Breast Cancer Surgery
Interventions: DEVICE: Vicryl plus and Monocryl plus|DEVICE: wound closure with Vicryl and Monocryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Telehealth on Feeding Exclusive Breastfeeding in the Perception of Insufficient Milk
Status: COMPLETED
Conditions: Breast Feeding|Exclusive Breastfeeding
Interventions: OTHER: Providing breastfeeding support with Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Salovum™ and SPC-Flakes™ on Abemaciclib-induced Gastrointestinal Toxicity in Early Breast Cancer
Status: RECRUITING
Conditions: Early-stage Breast Cancer|Diarrhea|Adverse Drug Event
Interventions: DRUG: SPC-flakes|DRUG: Salovum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home Neuromodulation of the Neurogenic Bladder in Chronic Spinal Cord Injury With Transcutaneous Tibial Nerve Stimulation
Status: COMPLETED
Conditions: Chronic Spinal Cord Injury|Neurogenic Bowel
Interventions: DEVICE: 4-week TTNS home-based protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic and Anxiety Efficacy of Preemptive Pregabalin
Status: UNKNOWN
Conditions: Analgesia|Anxiety|Arthroscopic Shoulder Surgery
Interventions: OTHER: Preoperative and postoperative anxiety measurement [Spielberger's State Anxiety Scale (STAI-S)] and [ Spielberg's State-Trait Anxiety Inventory (STAI-T) ]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine Versus Electroconvulsive Therapy in Depression
Status: SUSPENDED
Conditions: Depressive Disorder, Major|Bipolar Depression
Interventions: DRUG: Intravenous Ketamine|PROCEDURE: Electroconvulsive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
Status: COMPLETED
Conditions: Anterior Vaginal Wall Prolapse|Cystocele|Pelvic Organ Prolapse
Interventions: DEVICE: Polypropylene mesh (Polyform by Boston Scientific)|PROCEDURE: Porcine Dermis (Pelvicol by CRBard)|PROCEDURE: Anterior Colporrhaphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of AK111 Injection in the Treatment of Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis|Skin Diseases
Interventions: DRUG: AK111|DRUG: AK111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized and Automated Digital Coaching in People With Non-specific Chronic Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Personalized and automated digital coaching using a mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Remimazolam|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Durvalumab in Combination With Doxorubicin for Advanced Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Durvalumab+doxorubicin cobination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutathione (GSH) Supplementation After Hospitalization
Status: WITHDRAWN
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Liposomal Glutathione (GSH)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BRCA1-associated DNA Repair Dysfunction in Patients With Early Triple Negative Breast Cancer Treated With Neoadjuvant Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Early Triple Negative Breast Cancer
Interventions: DRUG: Doxorubicin, Paclitaxel, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.
Status: RECRUITING
Conditions: Gout
Interventions: DRUG: SIBP-R002|DRUG: SIBP-R002|DRUG: SIBP-R002|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Furosemide on Fluid Balance and Intra-abdominal Pressure in Critically Ill Patients
Status: UNKNOWN
Conditions: Intra-Abdominal Hypertension
Interventions: DRUG: furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Invossa K Injection in Patients Diagnosed With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Invossa K Inj.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Break Wave(TM) Extracorporeal Lithotripter First-in-Human Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Calculi|Urinary Calculi
Interventions: DEVICE: Break Wave extracorporeal lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Pyrotinib and Capecitabine For HER2 Positive Micro Invasive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Stage I
Interventions: DRUG: Capecitabine，Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Occupational Therapy Teleintervention in Pediatric
Status: NOT_YET_RECRUITING
Conditions: Telerehabilitation|Neurodevelopmental Disorders
Interventions: OTHER: occupation-based teleintervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement After Botulinum Toxin Injections to the Arms in Children With Cerebral Palsy
Status: TERMINATED
Conditions: Cerebral Palsy
Interventions: OTHER: physiotherapy|OTHER: Botulinum Toxin A and physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE
Status: NOT_YET_RECRUITING
Conditions: Meningioma
Interventions: DIAGNOSTIC_TEST: Brain Imaging with [Cu64]DOTATATE|PROCEDURE: Radio-guided Surgery With Neoprobe Utilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Antibody Persistence and Safety of GSK Biologicals' DTPa (INFANRIX) and dTpa (BOOSTRIX) Vaccines.
Status: TERMINATED
Conditions: Acellular Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: INFANRIX|BIOLOGICAL: BOOSTRIX|BIOLOGICAL: HAVRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: MicroRNA Profiles in Triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Plus Monoclonal Antibodies Acting on the CGRP Pathway for Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: DEVICE: Cathodal transcranial direct current stimulation|DEVICE: Sham cathodal transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (68Ga-PSMA-11 PET) for the Imaging of Prostate Cancer
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Castration-Resistant Prostate Carcinoma|Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 Gozetotide|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Bone Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Safety Study of Fluticasone Propionate (Fp) Multidose Dry Powder Inhaler (MDPI) and Fluticasone Propionate/Salmeterol (FS) MDPI in Patients With Persistent Asthma
Status: COMPLETED
Conditions: Persistent Asthma
Interventions: DRUG: Fp MDPI|DRUG: FS MDPI|DRUG: FLOVENT HFA|DRUG: ADVAIR DISKUS|DRUG: albuterol/salbutamol HFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Maxillary Sinusitis
Interventions: PROCEDURE: Specimen collection|PROCEDURE: Specimen collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrillation.
Status: UNKNOWN
Conditions: Ventricular Fibrillation|Ventricular Arrythmia|Polymorphic Ventricular Tachycardia|Sudden Cardiac Death|Heart Arrest|Cardiovascular Diseases|Cardiac Arrhythmia|Genetic Disease|Idiopathic Ventricular Fibrillation|Cardiac Arrest
Interventions: DIAGNOSTIC_TEST: ECG-Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fibrin Clot Properties and Blood Loss Following Coronary Artery By-pass Grafting
Status: COMPLETED
Conditions: Coronary Artery Disease|Internal Mammary-Coronary Artery Anastomosis|Coronary Artery Bypass|Blood Loss, Postoperative|Fibrinolysis
Interventions: PROCEDURE: Skeletonized LIMA|PROCEDURE: Pedicled LIMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft Recipients
Status: COMPLETED
Conditions: Graft Rejection|Kidney Failure|Kidney Transplantation
Interventions: DRUG: Cyclosporin or tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actuate 1901: 9-ING-41 in Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolitinib|DRUG: 9-ING-41
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nifedipine or Nifedipine Plus Indomethacin for Treatment of Acute Preterm Labor
Status: TERMINATED
Conditions: Preterm Labor
Interventions: DRUG: Nifedipine|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Early Childhood Obesity, Part 1: Long-term Follow-up
Status: COMPLETED
Conditions: Obesity|Water; Lack of|Childhood Obesity|Feeding Behavior|Mother-Child Relations|Dietary Habits
Interventions: BEHAVIORAL: Family Spirit Nurture (FSN)|OTHER: Control Group - Vehicle Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Dose Carfilzomib for Newly Diagnosed Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT