pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B1641003/KEYNOTE-0036)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: PF-05082566|DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
Status: ENROLLING_BY_INVITATION
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Upadacitinib|DRUG: Topical corticosteroids (TCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia
Status: COMPLETED
Conditions: Childhood Acute Promyelocytic Leukemia With PML-RARA|Myeloid Neoplasm
Interventions: DRUG: Arsenic Trioxide|DRUG: Cytarabine|OTHER: Diagnostic Laboratory Biomarker Analysis|DRUG: Idarubicin|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Mitoxantrone Hydrochloride|DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients
Status: COMPLETED
Conditions: Presence of COVID-19 Compatible CT Abnormalities
Interventions: DIAGNOSTIC_TEST: PET-CT of 18F-FDG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Intraocular Tamponade on Visual Perception
Status: UNKNOWN
Conditions: Retinal Detachment|Optic Neuropathy|Glaucoma
Interventions: DIAGNOSTIC_TEST: Electroretinogram|PROCEDURE: Vitrectomy operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIG Treatment for Refractory Immune-Related Adult Epilepsy
Status: TERMINATED
Conditions: Epilepsy, Cryptogenic|Epilepsy, Partial|Seizure Disorder|Autoimmune Diseases, Nervous System|Limbic Encephalitis
Interventions: DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Weight Loss Using Gastric Stimulation in Obese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Severe to Morbid Obesity and Type 2 Diabetes
Interventions: DEVICE: Enterra Therapy System (H9900014)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COmmuNity-engaged SimULation Training for Blood Pressure Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: OTHER: CONSULT-BP Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inhaled Morphine Compared With Morphine By Mouth in Treating Cancer Patients With Breakthrough Pain
Status: COMPLETED
Conditions: Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: morphine sulfate|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-label Extension Evaluating Methylphenidate Hydrochloride Extended Release in Adults With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Ritalin LA (methylphenidate hydrochloride extended release)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MARLINA - T2D : Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Linagliptin 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Soy Protein/Soy Fiber on Measures of Satiety
Status: COMPLETED
Conditions: Lack of Satiety
Interventions: OTHER: Satiety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Project 2 Airway Potential Hydrogen (pH) in Asthma
Status: RECRUITING
Conditions: Cystic Fibrosis|Asthma|Severe Persistent Asthma|Healthy
Interventions: DRUG: Glycine Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Study of TAK-850 in Comparison With Influenza Hemagglutinin (HA) Vaccine in Healthy Adult Participants
Status: COMPLETED
Conditions: Influenza Infection
Interventions: BIOLOGICAL: TAK-850|BIOLOGICAL: Influenza HA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Challenges in the Population of Nursing Homes' Residents
Status: ENROLLING_BY_INVITATION
Conditions: Nutritional Status|Nutrient Deficiency|Micronutrient Deficiency|Vitamin D Deficiency|Vitamin B 12 Deficiency|Folic Acid Deficiency|Iron-deficiency|Protein Deficiency|Sarcopenia|Obesity|Diet
Interventions: OTHER: Diagnostic Tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Rice Germ Supplementation on Body Composition, Metabolic Parameters, Satiating Capacity and Amino Acid Profiles in Obese Postmenopausal Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Rice Germ|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Effectiveness and Safety Study for RWJ-333369 as Adjunctive Therapy in Korean and Japanese Patients With Partial Onset Seizures
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: RWJ-333369
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Mannitol Inhalant Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant, Combined Interleukin 2 (Proleukin) and DTIC (Dacarbazine) in High-risk Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: DRUG: Proleukin and Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Postoperative Pain Following Oocyte Retrieval for Assisted Reproduction
Status: UNKNOWN
Conditions: Oocyte Retrieval|Postoperative Pain
Interventions: DRUG: Fentanyl|DRUG: Acetaminophen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|DRUG: Nemtabrutinib|PROCEDURE: Positron Emission Tomography and Computed Tomography Scan|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rifabutin Based Therapy for the Eradication of Staphylococcus Aureus Colonization in HIV Infected Adults
Status: TERMINATED
Conditions: Staphylococcus Aureus|HIV Infections
Interventions: DRUG: rifabutin plus trimethoprim sulfamethoxazole|DRUG: placebo plus trimethoprim-sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Carbamazepine for Prevention of Chemotherapy-induced Nausea and Vomiting
Status: UNKNOWN
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Measuring Gait And Self-Reported Pain In Patients With Osteoarthritis Of The Knee Using Placebo/Oxycodone/Celecoxib.
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DRUG: celecoxib|DRUG: Oxycodone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Safety and Efficacy of PBK_M2101
Status: RECRUITING
Conditions: Intestinal Disease|Colonic Diseases|Gastrointestinal Disease|Digestive System Disease
Interventions: DRUG: PBK_M2101 2-Day|DRUG: PBK_M2101 1-Day|DRUG: Oral Sulfate Tablet 2-Day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ODISEA Trauma: Parental Therapy Dispositive + Videofeedback 3.0
Status: NOT_YET_RECRUITING
Conditions: Parent-Child Relations|Parenting|Parent-child Problem
Interventions: BEHAVIORAL: Video-feedback ODISEA 3.0|BEHAVIORAL: ODISEA-DTP: parental therapy|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Phase I Cardiac Rehabilitation on the Prognosis of AMI Patients After PCI
Status: RECRUITING
Conditions: Acute Myocardial Infarction|Phase I Cardiac Rehabilitation
Interventions: BEHAVIORAL: Phase I Cardiac Rehabilitation Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Image Guided Intensity Modulated Reirradiation (IG-IMRT) With Cetuximab for Locoregionally Confined Recurrent Head and Neck Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Squamous Cell Cancer of the Head and Neck
Interventions: RADIATION: Radiation|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Neoadjuvant Therapy in Participants With International Federation of Gynecology and Obstetrics (FIGO) Stage IIIC/IV Ovarian, Tubal, or Peritoneal Cancer, Initially Unresectable
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: COMBINATION_PRODUCT: Hydroxychloroquine plus Nitazoxanide|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Vocal Function Exercises for Laryngeal Cancers
Status: COMPLETED
Conditions: Vocal Folds
Interventions: PROCEDURE: Vocal Function Exercises|PROCEDURE: Vocal Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Smartphone Technology: Young Adult Drinking
Status: COMPLETED
Conditions: Alcohol Use|Alcohol Drinking|Drinking Behavior
Interventions: OTHER: Smartphone breathalyzer device/app use|OTHER: BAC estimator app use|OTHER: Text messaging procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can we Reduce the Number of Vaccine Injections for Children?
Status: COMPLETED
Conditions: Invasive Meningococcal Disease
Interventions: BIOLOGICAL: Glyco-conjugate Neisseria meningitidis serogroup C (MenC) vaccine|BIOLOGICAL: Routine schedule immunisations except monovalent MenC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mifepristone Treatment for Patients With Non-psychotic Major Depressive Disorder Receiving Bilateral ECT
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Mifepristone|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Açaí Berry COVID-19 Anti-Inflammation Trial
Status: UNKNOWN
Conditions: COVID
Interventions: DIETARY_SUPPLEMENT: Açaí palm berry extract - natural product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of MK0928 in Adult Outpatients With Insomnia (0928-014)(COMPLETED)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: gaboxadol|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Safety and Efficacy of Fasudil in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Fasudil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Short Course Chemo-radiation Therapy in Locally Advanced Rectal Cancer Patients
Status: UNKNOWN
Conditions: Neo-adjuvant Short Course Chemo-radiotherapy in Locally Advanced Cancer Rectum
Interventions: DRUG: short course chemo-radiation with 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
Status: COMPLETED
Conditions: Dysfunctional Central Venous Access Catheters
Interventions: DRUG: tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Naevus Flammeus Using Intense Pulsed Light and Pulsed Dye Laser
Status: COMPLETED
Conditions: Port-Wine Stain
Interventions: DEVICE: Pulsed dye laser (Candela), Intense pulsed light (Palomar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Inhibitor Masking Device & Sodium Channel, Voltage Gated, Type IX Alpha Subunit (SCN9) Gene Expression
Status: TERMINATED
Conditions: Tinnitus
Interventions: DEVICE: The Inhibitor™ Tinnitus Masking Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation for the Foldax Tria Mitral Valve- India
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Valve Disease|Mitral Regurgitation|Mitral Stenosis|Mitral Valve Insufficiency
Interventions: DEVICE: Mitral Valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Reliability and Versatility of Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of Lip Defects
Status: UNKNOWN
Conditions: Lip Injury
Interventions: PROCEDURE: Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of large Lip defects post traumatic or post tumor resection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala on Coping With Fatigue, Psychological Well-Being and Stress in Patients Treated With Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis
Interventions: OTHER: Mandala coloring page
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion/Pleurectomy for Treatment of Pneumothorax?
Status: RECRUITING
Conditions: Primary and Secondary Spontaneous Pneumothorax
Interventions: DRUG: Paracetamol|DRUG: NSAID, Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Capecitabine and Radiation Therapy in Treating Patients With Nonmetastatic Breast Cancer After Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-hOspital Evaluation of Chest Pain Patients With sUspected Non ST-segment eLevation myocARdial Infarction Using the HEART-score With a Troponin Point-of-care Test
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Possible NSTE-ACS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host Disease
Status: TERMINATED
Conditions: Ocular Graft vs Host Disease|Dry Eye
Interventions: DRUG: rhDNase I|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Effect of Dialyzer Leaching of BPA From the Fresenius Optiflux 160NR Compared to the Nipro ELISIO-15H
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: FRESENIUS 160NR|DEVICE: NIPRO ELISIO-15H
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunologic Markers for the Differential Diagnosis Between Uveitis-TBC and Uveitis-SARC (TBC-SARC)
Status: UNKNOWN
Conditions: Uveitis Tuberculous|Uveitis Sarcoid
Interventions: DIAGNOSTIC_TEST: Analysis of aqueous humor and plasma samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Awareness of Osteoporosis in Diabetes Mellitus Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Osteoporosis|Osteoporosis Risk
Interventions: OTHER: Patient Participation Form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Link Between Mental Imagery and the Reduction of Fear in Imaginal Extinction
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BEHAVIORAL: Fear acquisition|BEHAVIORAL: Imaginal extinction|BEHAVIORAL: Reinstatement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecular Residual Disease (MRD) Guided Adjuvant ThErapy in Renal Cell Carcinoma (RCC)
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Pembrolizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214
Status: WITHDRAWN
Conditions: Drug Abuse|Healthy
Interventions: DRUG: TC-5214|DRUG: TC-5214 Placebo|DRUG: Ketamine|DRUG: Phentermine|DRUG: TC-5214|DRUG: TC-5214|DRUG: Phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Performance Assessment Study VitalSigns Camera
Status: UNKNOWN
Conditions: Healthy Humans|Vital Signs Monitoring
Interventions: DEVICE: Happy Flow / Baseline|DEVICE: Make-up|DEVICE: Sunglasses|DEVICE: Face mask|DEVICE: Minimum requirements camera|DEVICE: Worst case hardware|DEVICE: Damaged lens|DEVICE: Face or chest outside test frame
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interactive 3D Visualization Technique Used in Pulmonary Rehabilitation Programme in COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Interactive 3D visualization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Diagnostic Value of Ribosomal p2 Autoantibodies in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: Ribosomal p2 Autoantibodies as a Serum marker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rivaroxaban With Diosmin in Long-term Treatment of Deep Vein Thrombosis
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Postthrombotic Syndrome
Interventions: DRUG: Rivaroxaban|DRUG: Diosmin|OTHER: compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: Fingolimod|DRUG: Ofatumumab|DRUG: Siponimod|OTHER: Fingolimod placebo|OTHER: Siponimod placebo|OTHER: Ofatumumab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrigenomics Diet Intervention Study Comparing Effects of Western and Balanced Diet in Healthy Subjects
Status: COMPLETED
Conditions: Cardiovascular Diseases|Chronic Disease
Interventions: BEHAVIORAL: "Western" versus "balanced" macro nutrient diet composition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the 24/7 EEG SubQ System for Ultra Long-Term Recording of Patients With Temporal Lobe Epilepsy
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: 24/7 EEG™ SubQ system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Safety, Acceptability, Pharmacokinetics, and ex Vivo Pharmacodynamics of TMC278 Long Acting Formulation in HIV-1 Seronegative Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TMC278, Long acting (LA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Therapy for the Removal of Myoglobin Using the CytoSorb in Patients With Rhabdomyolysis
Status: WITHDRAWN
Conditions: Rhabdomyolysis
Interventions: DEVICE: CytoSorb Device|PROCEDURE: CVVH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chantix in Adult Smokers With Attention Deficit Hyperactivity Disorder (ADHD)
Status: TERMINATED
Conditions: Attention Deficit/Hyperactivity Disorder|Smoking Cessation
Interventions: DRUG: Varenicline (Chantix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Fully Human BCMA-targeting CAR (CT103A) Combined With Selinexor in Patients With Relapsed/Refractory Extramedullary Multiple Myeloma
Status: UNKNOWN
Conditions: Extramedullary Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: CT103A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Participants With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: GLPG1972|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: : External Shunt Versus Internal Shunt for Off Pump Glenn
Status: COMPLETED
Conditions: Cerebral Ischemia
Interventions: PROCEDURE: Internal shunt|PROCEDURE: External shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision Support System Based on Non-invasive Tele-monitoring of COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: Clinical decision support system based on non-invasive multimodal monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prostaglandin F2alpha in a Human Headache Model
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Prostaglandin F2alpha|DRUG: Isoton sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Remote Ischemic Conditioning for the Treatment of Stroke-related Insomnia
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Remote ischemic conditioning (RIC)|DEVICE: Sham remote ischemic conditioning (Sham-RIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capnography Monitoring in the Bronchoscopic Sedation
Status: COMPLETED
Conditions: Hypoventilation
Interventions: DEVICE: A nasal-oral cannula of capnography|OTHER: Observer Assessment of Alertness and Sedation scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Live Attenuated Influenza H5N2
Status: COMPLETED
Conditions: Influenza Due to Influenza A Virus Subtype H5N2
Interventions: BIOLOGICAL: Avian Flu Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CHAT at HOME Pilot Study
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: In-Person First Session|BEHAVIORAL: Second Caregiver|BEHAVIORAL: WiFi-enabled Scale|BEHAVIORAL: 10 Core Coaching Calls Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Hairstetics™ Anchoring System in Female Pattern Hair Loss (HAS-FPHL)
Status: UNKNOWN
Conditions: Female Pattern Baldness|Alopecia, Androgenetic
Interventions: DEVICE: Hairstetics™ anchoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Training Trial
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Computerized Progressive Attention Training|OTHER: Sham Comparator Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sternotomy PIFB Block in Open Heart Surgery
Status: RECRUITING
Conditions: Autonomic Nerve Block
Interventions: PROCEDURE: Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine|PROCEDURE: Pecto-intercostal Fascial Block with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: Prevena Incision Management System|OTHER: Conventional sterile dry wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Autologous iNSC-DAP in the Treatment of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: Autologous induced neural stem cell-derived DA precursor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Is Medicine for Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Heart Failure，Congestive|Heart Diseases
Interventions: OTHER: 15 Medically Tailored Meals (MTM) per week|OTHER: 14 Medically Tailored Meals (MTM) per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sedation by Dexmedetomidine and Propofol
Status: COMPLETED
Conditions: Anesthesia, Spinal
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Providing Breastfeeding Support After Discharge From Hospital to Improve Growth and Development of Malnourished Infants
Status: NOT_YET_RECRUITING
Conditions: Malnutrition, Infant|Breastfeeding, Exclusive
Interventions: OTHER: Breastfeeding peer support intervention|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cordis Bilateral AAA Device Compared to Open Surgical Repair of Abdominal Aortic Aneurysms (ARIBA)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Cordis AAA Bilateral Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4 Weeks Treatment With Empagliflozin (BI 10773) in Japanese Type 2 Diabetic Patients (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo (middle dose)|DRUG: Placebo|DRUG: BI 10773|DRUG: BI 10773|DRUG: BI 10773|DRUG: Placebo (high dose)|DRUG: BI 10773|DRUG: Placebo (low dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Short-Course Preoperative Stereotactic Body Radiation Therapy for Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Adenocarcinoma
Interventions: RADIATION: Preoperative SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIP Regimen Combined With Triplizumab Neoadjuvant Therapy for Locally Advanced Penile Cancer
Status: NOT_YET_RECRUITING
Conditions: Penile Cancer
Interventions: DRUG: Paclitaxel + Ifosfamide + Cisplatin & Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-volume PEG Plus Ascorbic Acid Versus Standard PEG Solution as Bowel Cleansing for Colonoscopy
Status: UNKNOWN
Conditions: Colonoscopy [E01.370.372.250.250.200]
Interventions: DRUG: polyethylene glycol, ascorbic acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART)
Status: COMPLETED
Conditions: HIV Infections|Hypertriglyceridemia
Interventions: DRUG: Fenofibrate|DRUG: Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: danoprevir|DRUG: ritonavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Feasibility Study of Peritoneal Dialysis With CLS PD, Which Removes Toxins and Maintains a Stable Ultrafiltration by Continuously Regenerating a Recirculating Intraperitoneal Fluid, in Patients With End Stage Renal Disease, ESRD, With PD Therapy.
Status: COMPLETED
Conditions: Peritoneal Dialysis
Interventions: DEVICE: lCarry Life System Peritoneal Dialysis (CLS PD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Retrospective Analysis of the Adherence to Clinical Practice Guidelines Using the "MedicBK" Digital Platform in Patients With Hypertension and Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Arterial Hypertension
Interventions: DRUG: Retrospective analysis of assigned treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DDS-25 Gauge in Patients With Macular Edema Secondary to Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DEVICE: Dexamethasone drug delivery system (DDS-25)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bowen Technique vs Muscle Energy Technique in Neck Pain.
Status: NOT_YET_RECRUITING
Conditions: Neck Pain|Musculoskeletal Manipulation
Interventions: OTHER: Bowen Therapy along with conventional therapy|OTHER: Muscle Energy Technique with Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Into Diagnostic and Prognostic Molecular and Imaging Biomarkers of Ocular Disorders Associated With Neurovascular Deregulation: Biocor Cohort
Status: RECRUITING
Conditions: Ocular Rosacea|Pachychoroid Disease
Interventions: DIAGNOSTIC_TEST: Schirmer test paper
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome
Status: TERMINATED
Conditions: Cystitis, Interstitial
Interventions: BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab|BIOLOGICAL: Tanezumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Food Timing Reduce Your Diabetes Risk?
Status: NOT_YET_RECRUITING
Conditions: Dietary Habits
Interventions: BEHAVIORAL: Day shift protocol - Diet order A-B|BEHAVIORAL: Day shift protocol - Diet order B-A|BEHAVIORAL: Night shift protocol - Diet order A-B|BEHAVIORAL: Night shift protocol - Diet order B-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Duration of Clopidogrel in Second-Generation Drug-Eluting Stents
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: 6-month dual anti-platelet therapy|DRUG: 12-month dual anti-platelet therapy|DEVICE: Zotarolimus eluting stent|DEVICE: Biolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Theater's Surgery Rehearsal Platform
Status: COMPLETED
Conditions: Cerebral Aneurysm Unruptured|Cerebral Aneurysm Ruptured
Interventions: OTHER: Active SRP cases|OTHER: Control cases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TGFβR-KO CAR-EGFR T Cells in Previously Treated Advanced EGFR-positive Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|EGFR Overexpression
Interventions: BIOLOGICAL: TGFβR-KO CAR-EGFR T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel/Ifosfamide/Cisplatin Chemotherapy for High Risk Pediatric Germ Cell Tumor
Status: RECRUITING
Conditions: Pediatric Germ Cell Tumor
Interventions: DRUG: TIP treatment (paclitaxel/ifosfamide/cisplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Glucomannan in Overweight Patients
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Glucomannan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of IBI324 in Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: BIOLOGICAL: IBI324|BIOLOGICAL: IBI324|BIOLOGICAL: IBI324|BIOLOGICAL: IBI324|BIOLOGICAL: IBI324
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2
Status: COMPLETED
Conditions: Early Caries Lesions
Interventions: DEVICE: CPP-ACP (GC Tooth Mousse)|DEVICE: CPP-ACP (GC MI Paste Plus)|DEVICE: Fluoride (Elmex Medical Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Moxifloxacin Versus Gatifloxacin on Corneal Epithelium Following Pterygium Excision
Status: UNKNOWN
Conditions: Primary Pterygium
Interventions: DRUG: Moxifloxacin ophthalmic solution 0.5% ; Gatifloxacin ophthalmic solution 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
Status: COMPLETED
Conditions: Operation Wound; Infection|Endometritis
Interventions: DRUG: Clorhexidine|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Prednisone|DRUG: Docetaxel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic/Pharmacodynamic Study of RO5185426 in Previously Treated Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: RO5185426|DRUG: RO5185426|DRUG: RO5185426|DRUG: RO5185426|DRUG: RO5185426
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Glycerol Trierucate on Clinical Course of Adrenoleukodystrophy
Status: TERMINATED
Conditions: Adrenoleukodystrophy
Interventions: DRUG: glyceryl trierucate/glyceryl trioleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Placebo|DRUG: azelastine Hcl|DRUG: azelastineHcl / fluticasone propionate|DRUG: fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GastrOesophageal Varices After Sustained Virological Response
Status: UNKNOWN
Conditions: Liver Diseases|Hepatitis C
Interventions: DIAGNOSTIC_TEST: Liver elastography|DIAGNOSTIC_TEST: Splenic elastography|DIAGNOSTIC_TEST: Gastrointestinal endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Mobile-health Pilot Experiment Targeting Mothers With Newborns in Rural Areas of San Juan Sacatepequez, Guatemala
Status: COMPLETED
Conditions: Exclusive Breastfeeding|Co-production of Health in Communities
Interventions: OTHER: Uni-directional SMS|DEVICE: Feature phone|OTHER: Virtual communities|OTHER: Hybrid setup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis|Seasonal Allergic Rhinitis|Ragweed Allergy|Birch Pollen Allergy
Interventions: OTHER: Ragweed pollen, birch pollen, clean air (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel Disease (IBD)
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Serum bovine immunoglobulin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Daratumumab Combined With Carfilzomib, Lenalidomide and Dexamethasone for Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib, lenalidomide, dexamethasone (KRd) + Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery
Status: COMPLETED
Conditions: Oral Cancer|Head and Neck Cancer|Free Flap|Hypotension
Interventions: DRUG: Epinephrine|DRUG: Norepinephrine|DRUG: Dobutamine|DRUG: Dopexamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-operative Ketorolac Administration Has no Pre-emptive Analgesic Effect Following Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketorolac Tromethamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Cross-training on an Immobilised Forearm
Status: RECRUITING
Conditions: Forearm Fracture
Interventions: PROCEDURE: isokinetic strengthening exercise|PROCEDURE: conventional exercise programm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Alternating and Intermittent Regimens of 2',3'-Dideoxycytidine and 3'-Azido-3'-Deoxythymidine in the Treatment of Patients With AIDS and Advanced ARC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Brain Stimulation Treatment for CLBP
Status: UNKNOWN
Conditions: Chronic Low Back Pain (CLBP)
Interventions: DEVICE: NIBS system for evaluation and treatment utilizing non invasive brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Allogeneic Anti-CD38 A2 Dimeric Antigen Receptor T Cells in Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: STI-1492
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT