pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing Tai Chi Chih and Relaxation Therapy in the Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BEHAVIORAL: Tai Chi Chih|BEHAVIORAL: Relaxation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Muscle Oxygenation in Treadmill and Cycle Ergometer Exercise
Status: NOT_YET_RECRUITING
Conditions: Muscle Oxygenation|Treadmill
Interventions: OTHER: Questionnare|DEVICE: Moxy Muscle Oxygen Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection
Status: NOT_YET_RECRUITING
Conditions: Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: S1|DRUG: Cetuximab|DRUG: Metronidazole|DRUG: Vitamin A|DRUG: Folic acid|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: HD-tACS|DEVICE: Sham HD-tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing EC-T Verses PCb in the Adjuvant Chemotherapy of Non-triple Negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of the PLHIV With Suboptimal Viral Suppression to Injectable Long-acting Antiretrovirals
Status: RECRUITING
Conditions: HIV-1-infection|Non-Adherence, Medication
Interventions: DRUG: cabotegravir/rilpivirine (600mg/ 900mg)|DRUG: Antiretroviral Combinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Combined With CapeOX Regimen in Perioperative Treatment of Resectable Locally Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Unresectable Gastric Adenocarcinoma
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roux-en-Y Versus Billroth II Reconstruction After Subtotal Gastrectomy in Gastric Cancer Comorbid With Type II Diabetes
Status: UNKNOWN
Conditions: Gastric Cancer|Type 2 Diabetes
Interventions: PROCEDURE: Stomach-small intestine reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
Status: COMPLETED
Conditions: Encephalopathy|Developmental Delay and Behavioral Changes|Cord Tumor Compression or Instability|Cord Tethering or Malformation
Interventions: PROCEDURE: Intermittent Propofol Sedation|PROCEDURE: Continuous Propofol Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tizanidine and Superficial Cervical Block on Pain After Thyroidectomy
Status: COMPLETED
Conditions: Thyroidectomy
Interventions: DRUG: Placebo|DRUG: Tizanidine|DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Pre-scan to Reduce Needle Redirection During Right Jugular Vein Cannulation
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Ultrasound pre-scan|PROCEDURE: Landmark guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase III Study to Evaluate Efficacy of Botulinum Toxin for Treating Epicondylitis
Status: COMPLETED
Conditions: Epicondylitis
Interventions: DRUG: Injection, botulinum toxin + corticoid|DRUG: Injection, placebo of toxin + corticoid|DRUG: Injection, botulinum toxin + placebo corticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy
Status: RECRUITING
Conditions: Acute Pain|Post Operative Pain|Pain
Interventions: DRUG: MR-107A-02|DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53 Mutated Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine and Cedazuridine|DRUG: Entrectinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teachers Leading the Frontlines (Tealeaf) - a Hybrid Effectiveness, Implement, and Context Trial
Status: ENROLLING_BY_INVITATION
Conditions: Child Behavior Disorders
Interventions: BEHAVIORAL: Tealeaf|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Manual Lymphatic Drainage on Swelling After Orthognathic Surgery - a Qualitative and 3D Facial Analysis.
Status: COMPLETED
Conditions: Postoperative Care/Methods|Drainage/Methods|Edema/Prevention & Control|Orthognathic Surgical Procedures/Adverse Effects
Interventions: OTHER: manual lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Dehydroepiandrosterone (DHEA) in Respiratory Pulmonary Hypertension in Adults
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Hypertension, Pulmonary
Interventions: DRUG: DHEA Treatment|DRUG: DHEA Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Para-Valvular Leak Closures
Status: COMPLETED
Conditions: Paravalvular Aortic Regurgitation|Paravalvular Mitral Regurgitation|Cardiac Valve Disease|Cardiac Catheterization
Interventions: DEVICE: transcatheter paravalvular leak closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: XELOX/mFOLFOX Plus Vitamin D3 vs. XELOX/mFOLFOX as Firstline Chemotherapy in mCRC
Status: UNKNOWN
Conditions: Vitamin D3
Interventions: DRUG: vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ERASE VITILIGO Early Repigmentation Approach for Stopping the Evolution of VITILIGO Prospective Multicentric Interventional Study With Blinded Evaluation
Status: RECRUITING
Conditions: Vitiligo
Interventions: OTHER: The resident memory T-cell infiltrate in perilesional vitiligo skin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Caring for Caregivers and People Living With Dementia Under Home-Based Primary Care
Status: RECRUITING
Conditions: Dementia|Quality of Life|Caregiver Stress
Interventions: OTHER: Dementia Care Quality at Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cycling of Sedative Infusions in Critically Ill Pediatric Patients
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: DRUG: Midazolam|DRUG: Normal saline|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Behavioral Economics Incentives Strategies for Health
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: OTHER: Prize incentive - Low|OTHER: Prize incentive - High|OTHER: Escalating payment incentive|OTHER: Travel Voucher|OTHER: Standard care|BEHAVIORAL: Fixed Incentive - Prize|BEHAVIORAL: Loss Aversion - Prize|BEHAVIORAL: Lottery - Prize|BEHAVIORAL: Fixed Incentive - Voucher|BEHAVIORAL: Loss Aversion - Deposit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trastuzumab in a Neo-adjuvant Regimen for HER2+ Breast Cancer - the TRAIN Study
Status: COMPLETED
Conditions: Breast Cancer|HER2 Positive
Interventions: DRUG: paclitaxel, trastuzumab and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome|Alzheimer Disease
Interventions: BEHAVIORAL: Remote Low|BEHAVIORAL: Remote High|BEHAVIORAL: Personal Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CGM and DFU Healing Post-discharge
Status: RECRUITING
Conditions: Diabetic Foot|Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown
Interventions: DEVICE: Real Time Continuous Glucose Monitoring (rt-CGM)|OTHER: Fingerstick blood glucose (FBG) monitoring|BEHAVIORAL: Diabetes Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants
Status: COMPLETED
Conditions: Vaccines, Pneumococcal
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 7vPnC|BIOLOGICAL: Pediacel|BIOLOGICAL: NeisVac-C|BIOLOGICAL: Menitorix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Kinesiotape Technique on Wrist Among Chronic Stroke Patients
Status: UNKNOWN
Conditions: Chronic Stroke
Interventions: OTHER: Kinsiotaping for wrist flexor muscles|OTHER: Kinesiotaping for wrist extensor muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2)
Status: RECRUITING
Conditions: Chronic Sinusitis|Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: LYR-210|DRUG: Sham procedure control|OTHER: Background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telitacicept for the Treatment of Connective Tissue Disease-associated Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Connective Tissue Diseases|Thrombocytopenia
Interventions: BIOLOGICAL: Telitacicept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis ALS
Interventions: DRUG: Astaxanthin|DRUG: Protandim|DRUG: Melatonin|DRUG: MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Small Daily Doses of B-carotene on Breast Milk Retinol
Status: COMPLETED
Conditions: Vitamin A Status
Interventions: DIETARY_SUPPLEMENT: b-carotene|DIETARY_SUPPLEMENT: retinyl palmitate|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Refreshing Older Adults' Driving Skills (ROADSkills) Program
Status: RECRUITING
Conditions: Drive
Interventions: BEHAVIORAL: ROADskills program|BEHAVIORAL: Healthy Aging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fusion After ALIF With an Osteoinductive Material or With Homologus Bone
Status: COMPLETED
Conditions: Fusion of Spine, Lumbar Region
Interventions: DEVICE: NanoBone|DEVICE: Homologous Bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using EMG of the Healthy Hand to Control TENS of the Affected Hand in Hemiparetic Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: EMG and TENS|DEVICE: TENS only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell Lymphomas
Status: TERMINATED
Conditions: Lymphoma, T-Cell, Cutaneous|Mycosis Fungoides
Interventions: DRUG: Methotrexate|DRUG: Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Injured Knees From osteoArthritis: Severity Outcomes
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Post-traumatic Osteoarthritis|ACL Tear
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Probiotic on Constipation in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Constipation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei DG (Enterolactis duo®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effects of Increased Endogenous Erythropoietin After Normobaric Oxygen Breathing
Status: WITHDRAWN
Conditions: Healthy|Coronary Artery Bypass Graft
Interventions: OTHER: pure oxygen breathing versus air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Biological Effects of the Addition of Zoledronic Acid to Pre-operative Chemotherapy in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 5-FU, Epirubicin, Cyclophosphamide, Docetaxel|DRUG: 5-FU, Epirubicin, Cyclophosphamide, Docetaxel, Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fuzeon (Enfuvirtide) With an Integrase Inhibitor Plus Optimized Background in Treatment-Experienced HIV-1 Infected Patients
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: enfuvirtide [Fuzeon]|DRUG: Optimized background ARV|DRUG: Integrase inhibitor|DRUG: enfuvirtide [Fuzeon]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Child in Context Intervention Study
Status: COMPLETED
Conditions: Rehabilitation|Brain Injuries|Brain Injury, Chronic|Brain Diseases|Family|Childhood Brain Tumor|Child Behavior|Parenting
Interventions: OTHER: Family centered in-home rehabilitation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing an EEG Probe for Studying and Modulating Cognitive Control
Status: COMPLETED
Conditions: Post-stroke Depression
Interventions: PROCEDURE: Transcranial Electrical stimulation|PROCEDURE: Transcutaneous direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Status: RECRUITING
Conditions: Recurrent World Health Organization (WHO) Grade II Glioma|Low-grade Glioma|High Grade Glioma
Interventions: DRUG: Everolimus|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients
Status: RECRUITING
Conditions: Nausea and Vomiting, Postoperative
Interventions: DRUG: Amisulpride Injection|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immunoscore as Decision Guidance for Adjuvant Chemotherapy in Colon Cancer
Status: NOT_YET_RECRUITING
Conditions: Colon Cancer Stage III
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Fluorouracil|DRUG: Leucovorin|DEVICE: Immunoscore® assay|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rescue Therapy for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Bismuth Potassium Citrate|DRUG: Tetracycline,Metronidazole|DRUG: Minocycline,Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use
Status: RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: BEHAVIORAL: Non-menthol Cigarette Smoking|BEHAVIORAL: Menthol Cigarette Smoking|BEHAVIORAL: Synthetic Cooling Agent Cigarette Smoking|BEHAVIORAL: Usual Brand Cigarette Smoking|DIAGNOSTIC_TEST: Spirometry|OTHER: Questionnaire Administration|DIAGNOSTIC_TEST: Nasal Epithelial Lining Fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral SAHA (Suberoylanilide Hydroxamic Acid) in Advanced Cutaneous T-cell Lymphoma (0683-001)
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma|Sezary Syndrome|Mycosis Fungoides
Interventions: DRUG: MK0683, vorinostat, Suberoylanilide Hydroxamic Acid (SAHA) / Duration of Treatment 6 Months
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ocean Sound In Premature Retinopathy Examination
Status: COMPLETED
Conditions: Premature Retinopathy|Pain
Interventions: OTHER: Ocean sound|OTHER: Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Lacosamide Tablets|DRUG: Lacosamide extended release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The SASA! Study: An Evaluation of a Community Intervention to Address Gender-based Violence and Reduce HIV/AIDS Risk in Uganda
Status: UNKNOWN
Conditions: Intimate Partner Violence|HIV
Interventions: BEHAVIORAL: SASA!|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trastuzumab Biosimilar (Samfenet®) Plus Treatment of Physician's Choice (TPC) in Patients With HER2-positive Solid Tumor
Status: UNKNOWN
Conditions: HER-2 Protein Overexpression|HER-2 Gene Amplification
Interventions: DRUG: Trastuzumab biosimilar|DRUG: Gemcitabine Hydrochloride|DRUG: Irinotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Mindfulness-Based Stress Reduction Meditation Practice on Patients After Cardiac Rehabilitation.
Status: NOT_YET_RECRUITING
Conditions: Cardiac Disease
Interventions: OTHER: Cardiac rehabilitation with Mindfulness-Based Stress Reduction (MBSR)|OTHER: Conventional cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Xenogenic Keratoplasty From Porcine Cornea
Status: SUSPENDED
Conditions: Porcine Corneal Xenograph
Interventions: GENETIC: Xenogenic cornea|GENETIC: homogenic cornea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Full-Endoscopic vs Open Discectomy for the Treatment of Symptomatic Lumbar Herniated Disc
Status: TERMINATED
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: Lumbar discectomy Open|PROCEDURE: Lumbar discectomy Endoscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double-Blind, Phase III, Adjuvant-Controlled Study of the Effect of 10 Units of HIV-1 Immunogen (Remune) Compared to Incomplete Freund's Adjuvant (IFA) Alone Every 12 Weeks on AIDS-Free Survival in Subjects With HIV Infection and CD4 T-Lymphocytes Between 300 and 549 Cells/microL Rega
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 Immunogen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 IV Gallium Study for Patients With Cystic Fibrosis (IGNITE Study)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Gallium nitrate|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trenev Trio®/Healthy Trinity® for Recurrent Gastrointestinal Symptoms
Status: UNKNOWN
Conditions: Recurrent Gastrointestinal Symptoms
Interventions: DIETARY_SUPPLEMENT: Trenev Trio®/Healthy Trinity®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device
Status: RECRUITING
Conditions: Obstructive Sleep Apnea of Adult
Interventions: BEHAVIORAL: Oropharyngeal Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Reduction Induced by CPAP in Sleep Apnea Patients at High Cardiovascular Risk : OPTISAS 2 Study
Status: UNKNOWN
Conditions: Sleep Apnea Syndromes|High Cardiovascular Risk
Interventions: DEVICE: CPAP treatment|DEVICE: CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia
Status: UNKNOWN
Conditions: Aspirin|Dyspepsia
Interventions: DRUG: esomeprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Uterine Healing After Caesarean Section: CLInico-ECHOgraphic and Anatomopathologic COrrelation
Status: NOT_YET_RECRUITING
Conditions: Assessment of Uterine Healing
Interventions: PROCEDURE: uterine biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TACE(Transcatheter Arterial Chemoembolization ) Associated With Systemic Chemotherapy Versus Systemic Chemotherapy Alone in Patients With Unresectable CRLM(Colorectal Liver Metastases)
Status: UNKNOWN
Conditions: Colorectal Adenocarcinoma Metastatic to the Liver
Interventions: DRUG: TACE|DRUG: chemotherapy±target therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MCE-new for Detection of Gastric Lesions
Status: NOT_YET_RECRUITING
Conditions: Capsule Endoscopy
Interventions: DEVICE: undergo NaviEC-2000Pro Gastro Scan mode|DEVICE: NaviEC-2000Pro Routine gastric examination|DEVICE: NaviEC-1000 Routine gastric examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety Study of Darinaparsin in Combination With Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) to Treat Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: darinaparsin|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPONDER-HF Trial
Status: RECRUITING
Conditions: Heart Failure|Heart Failure, Diastolic
Interventions: DEVICE: Corvia Atrial Shunt System / IASD System II|OTHER: Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Cognitive Effects of 6 Weeks Administration With a Probiotic
Status: COMPLETED
Conditions: Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei Lpc-37|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inpatient Post Admission Cognitive Therapy (PACT) for the Prevention of Suicide Attempts
Status: COMPLETED
Conditions: Suicide, Attempted
Interventions: BEHAVIORAL: Post Admission Cognitive Therapy (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.
Status: NOT_YET_RECRUITING
Conditions: Outcome
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Fractures
Interventions: DRUG: Tranexamic Acid Injectable Solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research With Retinal Cells Derived From Stem Cells for Myopic Macular Degeneration
Status: WITHDRAWN
Conditions: Myopic Macular Degeneration
Interventions: BIOLOGICAL: MA09-hRPE Cellular Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Plasma Cell Leukemia|Plasmacytoma|Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Panobinostat|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Insulin Versus Autologous Serum After Corneal Surgeries
Status: UNKNOWN
Conditions: Corneal Epithelial Wound
Interventions: DRUG: Insulin|DRUG: autologous serum (AS)|DRUG: conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Overactive Bladder|Mild Cognitive Impairment
Interventions: DRUG: fesoterodine 4mg|DRUG: Oxybutynin|DRUG: placebo|DRUG: fesoterodine 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Oral Feeding in Infants With Pierre Robin Syndrome
Status: NOT_YET_RECRUITING
Conditions: Pierre Robin Syndrome
Interventions: DEVICE: intermittent oro-esophageal tube feeding|DEVICE: gastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heterologous Prime-boost Immunization With an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming With an Inactivated SARS-CoV-2 Vaccine
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: inactive SARS-CoV-2 vaccine (Vero cell)|BIOLOGICAL: Low dose aerosolized Ad5-nCoV|BIOLOGICAL: High dose aerosolized Ad5-nCoV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Simulated Forest Immersion Therapy on Pain and Anxiety in Patients Axial Spondyloarthritis (axSpA)
Status: ENROLLING_BY_INVITATION
Conditions: Axial Spondyloarthritis
Interventions: OTHER: Humidified Forest Oils|OTHER: Virtual Reality using Surface Pro and headphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Intravenous Carbamazepine (IV CBZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alfentanil: Simultaneous Testing Pilot
Status: COMPLETED
Conditions: Evaluate Two Paradigms for Simultaneous Assessment of Hepatic and Intestinal CYP3A
Interventions: DRUG: Alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Control in Colorectal Surgery: Liposomal Bupivacaine Block Versus Intravenous Lidociane
Status: COMPLETED
Conditions: Colorectal Disorders
Interventions: DRUG: Exparel|DRUG: IV Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protonics Knee Brace Versus Hamstring Resisted Exercise (HRE) on Individuals With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Protonics Knee brace|DEVICE: Sports Cords
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empowering Veterans to Actively Communicate and Engage in Shared Decision Making in Medical Visits, A Randomized Controlled Trial
Status: RECRUITING
Conditions: Diabetes Mellitus (Type 2)
Interventions: BEHAVIORAL: Speak Up! Video
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: How v. How and Why Nudges and Rewards
Status: COMPLETED
Conditions: Control Condition|How Incentive Receive|How Incentive Holdout|How Incentive Ineligible|How and Why Incentive Receive|How and Why Incentive Holdout|How and Why Incentive Ineligible
Interventions: BEHAVIORAL: How Nudge|BEHAVIORAL: How and Why Nudge|BEHAVIORAL: Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study on the Relationship Between Asymmetric Vascular Sign of Cortex and Prognosis in Massive Cerebral Infarction
Status: UNKNOWN
Conditions: Cerebral Infarction|Cerebral Edema
Interventions: DRUG: sodium aescinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Check of Optical Features and Accuracy of the Zeiss ZO Lens After Selection and Calculation With OKULIX
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Invent ZO|DEVICE: XL Stabi ZO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: First in Man Study of the JenaValve TAVI Plus System Transfemoral
Status: TERMINATED
Conditions: Aortic Valve Stenosis|Heart Valve Diseases|Heart Diseases|Cardiovascular Diseases
Interventions: DEVICE: JenaValve Pericardial TAVR System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
Status: RECRUITING
Conditions: Gulf War Syndrome|Gulf War Illness|Headache|Muscle Pain|Joint Pain
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Dysfunction in Late-Life Depression
Status: RECRUITING
Conditions: Late Life Depression|Cognitive Decline|Depressive Disorder, Treatment-Resistant|Levodopa|Gait Impairment
Interventions: DRUG: L-Dopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Trial of BGJ398/BYL719 in Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: BGJ398|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus Lenalidomide in Patients With Mucosa Associated Lymphoid Tissue
Status: COMPLETED
Conditions: Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT)
Interventions: DRUG: Rituximab and Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bariatric Surgery on Hepatic Metabolism in Non-Alcoholic Fatty Liver Disease
Status: ENROLLING_BY_INVITATION
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: PROCEDURE: bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the SurVeil™ Drug-Coated Balloon
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease|Peripheral Vascular Disease|Artery Disease, Peripheral|Femoropopliteal Artery Occlusion
Interventions: DEVICE: Surmodics SurVeil DCB|DEVICE: Medtronic IN.PACT Admiral DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Analgesia For Removal Of Wound Vac Dressings
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Placebo-Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Lower Maintenance Dose of Ticagrelor Early After Myocardial Infarction (ELECTRA) Pilot Study
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Ticagrelor 90 mg|DRUG: Ticagrelor 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GAIA-102 Intraperitoneal Administration in Patients With Advanced Gastrointestinal Cancer of Microsatellite Stable With Malignant Ascites
Status: RECRUITING
Conditions: Gastric Cancer|Pancreatic Cancer
Interventions: BIOLOGICAL: Phase I part|BIOLOGICAL: Phase II part
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Very Small Embryonic-like Stem Cells and the Prognosis of Coronary Artery Disease Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Intensive statin|DRUG: Routine statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Lu AG06466 in Participants With Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: Lu AG06466|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALL
Status: WITHDRAWN
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Tisagenlecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Program Of Exercises During The Hospitalization Of Children And Adolescents With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis|Cystic Fibrosis in Children|Cystic Fibrosis Pulmonary Exacerbation|Cystic Fibrosis With Exacerbation
Interventions: OTHER: Exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma
Status: COMPLETED
Conditions: Picoseconds Laser|Melasma
Interventions: DEVICE: Fractional Picosecond 1,064 nm laser|DRUG: 4% hydroquinone cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Responses After 12-week Hypocaloric Diet Supplemented With a Cereal-based Plant Protein Biscuit
Status: COMPLETED
Conditions: Appetite
Interventions: OTHER: wheat biscuit enriched with plant proteins|OTHER: common wheat biscuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Pembrolizumab (K)|DRUG: Placebo (P)|DRUG: Paclitaxel (X)|DRUG: Doxorubicin (A)|DRUG: Epirubicin (E)|DRUG: Cyclophosphamide (C)|DRUG: Endocrine therapy|RADIATION: Radiation therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interactions of Valsartan and Hydrochlorothiazide
Status: COMPLETED
Conditions: Healthy Normotensive Participants
Interventions: DRUG: Valsartan/Hydrochlorothiazide|DRUG: Valsartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Montelukast in Mild Asthmatic Children With Allergic Rhinitis (0476-367)
Status: COMPLETED
Conditions: Asthma|Allergic Rhinitis
Interventions: DRUG: montelukast sodium|DRUG: inhaled corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Pulmicort Respules in Japanese Adult Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide|DRUG: Pulmicort Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of HoLEP vs. PVP in Treating BPH in Patients With Bleeding Tendency
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: HoLEP|PROCEDURE: Greenlight laser PVP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Leritrelvir(RAY1216) in Participants With Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Leritrelvir(Ray1216)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG
Status: UNKNOWN
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Amiodarone|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Possible Effect Of Amniotic Fluid pH On Neonatal Morbidities In Maternal Inflammation/Infection Associated Pregnancies
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Transient Tachypnea of Newborn|Intrauterine Growth Retardation
Interventions: DEVICE: Amniotic fluid analysis by blood gas device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Articaine Plus Dexmedetomidine in Supraclavicular Block
Status: RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: DRUG: Articaine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics
Status: WITHDRAWN
Conditions: Colorectal Cancer|Photodynamic Diagnosis
Interventions: DRUG: Cysview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor
Status: NOT_YET_RECRUITING
Conditions: Desmoplastic Small Round Cell Tumor|Synovial Sarcoma
Interventions: DRUG: Signifor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positional Therapy to Treat Obstructive Sleep Apnea in Stroke Patients
Status: TERMINATED
Conditions: Stroke, Ischemic|Obstructive Sleep Apnea
Interventions: DEVICE: Positional therapy belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analyzes of Nasal Tissue-resident Memory Immune Cells and Peripheral Memory Cells Able to Migrate to Airway Tissues (MUCOVAC)
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DEVICE: Nasal tissue-resident memory T and B cells|DEVICE: Nasal fluid sampling|DEVICE: Saliva sampling|OTHER: Blood sampling|DIAGNOSTIC_TEST: ELISA|DIAGNOSTIC_TEST: Neutralization test|DIAGNOSTIC_TEST: ELISPot|DIAGNOSTIC_TEST: Transcriptomics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adherence to Stimulant Treatment in Attention-Deficit Hyperactivity Disorder (ADHD) Patients (ASTA)
Status: TERMINATED
Conditions: ADHD
Interventions: DRUG: Immediate release methylphenidate (Medikinet®)|DRUG: Extended release methylphenidate (Medikinet retard®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT