pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development of Structured Exercise Program for T2DM Management
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|High-Intensity Interval Training|Resistance Training|Oxidative Stress|Physical Fitness
Interventions: BEHAVIORAL: structured combined exercise|BEHAVIORAL: cardiorespiratory exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Adenocarcinoma|Stage IIA Esophageal Cancer|Stage IIB Esophageal Cancer
Interventions: DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|BIOLOGICAL: Panitumumab|OTHER: Pharmacological Study|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three-Axis Wearable Adaptive Vestibular Stimulator
Status: RECRUITING
Conditions: Motion Sickness
Interventions: DEVICE: Galvanic Vestibular Stimulation (GVS)|OTHER: Flight simulations in virtual reality (VR)|OTHER: 3-DOF Bertec Portable Essential's dual-balance force plate system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combined Nutritional and Exercise Strategies to Reduce Liver Fat Content in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Postprandial Lipids Metabolism|Type 2 Diabetes
Interventions: OTHER: Rich in MUFA diet -PA|OTHER: high fiber/low glycemic index diet + pa|OTHER: Rich in MUFA diet+PA|OTHER: High fibre/low glycemic index diet-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome
Status: COMPLETED
Conditions: Aortic Stenosis|Hypoplastic Left Heart Syndrome
Interventions: PROCEDURE: Fetal Aortic Valvuloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Radiation Therapy in Treating Women With Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: paclitaxel|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
Status: COMPLETED
Conditions: Thyroid Disease|Parathyroid Disease
Interventions: DRUG: PIPC piperacillin sodium|DRUG: CEZ, cefazolin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Intubation on Intra-ocular Pressure and Optic Nerve Sheath Diameter
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: PROCEDURE: McGrath videolaryngoscopy|PROCEDURE: C-MAC videolaryngoscopy|DEVICE: Direct laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Multidisciplinary Program on Falls in Elderly Inpatients
Status: UNKNOWN
Conditions: Falls Among Elderly Inpatients
Interventions: OTHER: The multidisciplinary prevention program called "IPR" (in French "Identifier, Prévenir, Relever")
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Geriatric Questionnaires to Predict Toxicities of CDK 4/6 Inhibitors in Older Breast Cancer Patients?
Status: UNKNOWN
Conditions: Can the Geriatric Questionnaires Predict Adverse Effects in Geriatric Breast Cancer Patients Treated With Cyclin-dependent Kinase 4 and 6 Inhibitors
Interventions: DRUG: Palbociclib 125mg and Ribociclib 600 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IN-USE TOLERANCE STUDY UNDER DERMATOLOGICAL AND OPHTHALMOLOGICAL CONTROLS AND EFFICACY ASSESSMENT (Face Balm)
Status: COMPLETED
Conditions: Hypersensitive|Reactive and Intolerant Skin|Redness-prone Skin|Stinger Subjects
Interventions: OTHER: Cosmetic product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of V260 in Healthy Chinese Adults, Children and Infants (V260-028)(COMPLETED)
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Rotavirus Vaccine, Live, Oral, Pentavalent|BIOLOGICAL: Comparator: Placebo|BIOLOGICAL: Rotavirus Vaccine, Live, Oral, Pentavalent|BIOLOGICAL: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: INSPIRE Trial for Skin and Soft Tissue Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin and Soft Tissue (SST) Infection
Interventions: OTHER: Arm 1: Routine Care|OTHER: Arm 2: INSPIRE Stewardship Bundle for Skin and Soft Tissue Infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD
Status: TERMINATED
Conditions: Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: STAKEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Health Benefits of Conjugated Linoleic Acid (CLA) for Asthma & Allergy
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Conjugated Linoleic Acid (CLA)|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Removal Capacities of the Theranova Membrane by Proteomic Investigations
Status: UNKNOWN
Conditions: Dialysis Membrane Reaction
Interventions: DEVICE: Hemodialysis with Theranova|DEVICE: Hemodialysis with FX1000|DEVICE: Hemodiafiltration with FX1000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy, Safety and Immunogenicity of Subcutaneous HX575 in the Treatment of Anemia Associated With Chronic Kidney Disease (SWEEP)
Status: WITHDRAWN
Conditions: Anemia|Chronic Renal Insufficiency
Interventions: DRUG: HX575 solution for s.c. administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Adenocarcinoma Signature Stratification for Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer Metastatic|Pancreatic Ductal Adenocarcinoma|Advanced Pancreatic Cancer
Interventions: DRUG: Folfirinox|DRUG: Gemcitabine/nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Combined Effect of Low Level Laser Therapy and Manual Lymph Drainage on Reducing Body Circumference
Status: TERMINATED
Conditions: Circumference Reduction
Interventions: DEVICE: Erchonia® Verju™ Laser|DEVICE: Green PRESS 8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of ISOThrive on Bodyweight, Body Composition, Hunger/Satiety and Cardiac Risk Measures in Overweight Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: ISOThrive Supplement|DIETARY_SUPPLEMENT: Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating the Role of the Polyol Pathway in the Central Nervous System
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: OTHER: Brain MRS during hyperglycemic clamp|OTHER: Analysis of Metabolites in cerebrospinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Participation in Pulmonary Rehabilitation Through Peer Support and Storytelling
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Telephonic Peer Coaching|BEHAVIORAL: Storytelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Postoperative Residual Curarization|Postoperative Residual Weakness
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate Safety and Maximum Tolerated Dose of BAY1000394 Given in a 4 Week on / 2 Week Off Schedule in Subjects With Advanced Malignancies
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAY1000394
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A RCT for Y-Knot All-suture Anchor in Ankle Ligaments Injury Repair
Status: COMPLETED
Conditions: Ligament Injury
Interventions: DEVICE: Y-Knot all-suture anchor|DEVICE: Biocomposite suture anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Hyaluronic Acid and Platelet Rich Fibrin Injection Efficacy in Interdental Papilla Reconstruction
Status: RECRUITING
Conditions: Interdental Papilla Loss
Interventions: BIOLOGICAL: Injection|DRUG: Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Peg-ASP-based CCRT in Early Stage ENKTL
Status: RECRUITING
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: COMBINATION_PRODUCT: Pegaspargase combined with concurrent radiotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor, Sensory, and Autonomic Function in Traumatic Spinal Cord Injury After the LION Procedure.
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: LION procedure|DEVICE: NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Rehabilitation During Neoadjuvant Therapy for Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Questionnaires|OTHER: Exercise|OTHER: Nutrition Counseling|BEHAVIORAL: Phone Calls|OTHER: Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Medtronic Endeavor III Drug Eluting Coronary Stent System Clinical Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Coronary Stenting|DEVICE: Percutaneous Coronary Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiplaque Efficacy of Two Novel Commercially Available Herbal Toothpastes.
Status: COMPLETED
Conditions: Gingivitis|Plaque, Dental
Interventions: DRUG: salvadora|DRUG: Eucalyptus Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Controlled Comparison of a Traditional Dressing Versus a Biologic Dressing Composed of Fetal Fibroblasts and Keratinocytes in Association With a Collagen Matrix on Skin Donor Sites
Status: TERMINATED
Conditions: Split Thickness Skin Graft|Wound Healing
Interventions: BIOLOGICAL: biological dressing|OTHER: Paraffin gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pregabalin on Pain After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Primary Total Knee Arthroplasty
Interventions: DRUG: Pregabalin 50mg|DRUG: Pregabalin 100mg|DRUG: Pregabalin 150mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romanian Kidney Transplant Cardiovascular Risk Registry
Status: UNKNOWN
Conditions: Kidney Transplant; Complications|Cardiovascular Diseases
Interventions: DEVICE: Bioimpedance Spectroscopy|DEVICE: Arterial Stiffness|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Lung ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Study for the Evaluation of the Cementless Anatomic Femoral Stem Minimax -Launay
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Osteoarthritis|Secondary Osteoarthritis|Traumatic Arthritis|Rheumatoid Arthritis|Congenital Hip Dysplasia|Avascular Necrosis|Fracture; Femur, Head
Interventions: DEVICE: MiniMAX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: Talactoferrin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Digital Cognitive Behavioral Therapy for Hazardous Alcohol Use: A Pilot Study in South Korea
Status: COMPLETED
Conditions: High-risk Drinkers|Hazardous Alcohol Use
Interventions: DEVICE: SOBER, mobile Application providing digital CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis
Status: COMPLETED
Conditions: Central Nervous System Metastases|HER2-positive Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: lapatinib ditosylate|DRUG: everolimus|DRUG: capecitabine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Training Program With Blood Flow Restriction in Children With Cerebral Palsy - EMBRIN: Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: 10-week gait training program combined with simultaneous blood flow restriction (BFR).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC)
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AC-170 0.24%|DRUG: AC-170 0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs
Status: RECRUITING
Conditions: HIV Infections|Opioid-Related Disorders|Pre-Exposure Prophylaxis (PrEP)
Interventions: BEHAVIORAL: SIRI Checklist|BEHAVIORAL: Enhanced Peer Recovery Coach|BEHAVIORAL: SIRI Checklist + Enhanced Peer Recovery Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of LY900014 Administered in Participants With Type 1 Diabetes Using an Insulin Pump
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro (Humalog)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Tripolar Radiofrequency on Acne Scar
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic|Scar|Radiofrequency
Interventions: DEVICE: Tripolar radiofrequency therapy|DRUG: medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retinal Pigment Epithelial Characteristics in Eyes With Neovascular Age-related Macular Degeneration Following Long-term Treatment With Anti Neovascular Endothelial Growth Factor
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DEVICE: OCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Efficacy of Low Dose Vaginal Estrogens in the Treatment of Atrophic Vaginitis
Status: TERMINATED
Conditions: Atrophic Vaginitis
Interventions: DRUG: Estriol|DRUG: Estradiol valerate|DRUG: Vanicream Lite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between a 1L of Polyethylene Glycol+Ascorbic Acid as a Split Dose Bowel Preparation for Colonoscopy
Status: UNKNOWN
Conditions: Colon Adenoma|Colonic Polyp
Interventions: DRUG: CleanViewAL|DRUG: SUPREP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Kineret (Anakinra), in Adult Patients With Colchicine-Resistant Familial Mediterranean Fever
Status: COMPLETED
Conditions: Familial Mediterranean Fever
Interventions: DRUG: Kineret
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.
Status: UNKNOWN
Conditions: Palliative Care|Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Diabetes|Cancer|Terminal Cancer|Terminal Illness|End Stage Cancer|Advanced Cancer
Interventions: DEVICE: Continuous Glucose Monitoring|DEVICE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Rifampin on the Pharmacokinetics of Dapagliflozin in Healthy Subjects
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: ACTIV-5 / Big Effect Trial (BET-A) for the Treatment of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Placebo|DRUG: Remdesivir|BIOLOGICAL: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Metformin on Hepatic FFA Metabolism
Status: COMPLETED
Conditions: Type 2 Diabetes|Dyslipidemia
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Dry Needling With the Fascial Winding Technique in the Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Dry Needling with Fascial Winding Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patients Affected With SARS-Cov-2
Status: UNKNOWN
Conditions: COVID|Acute Respiratory Distress Syndrome|Endothelial Dysfunction
Interventions: OTHER: Physiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Probiotics on Skin Hydration in Youth With Mild Acne
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris|Hydration Acne
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Emergence Agitation Between Sevoflurane and Desflurane Anesthesia After Orthognathic Surgery
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.
Status: RECRUITING
Conditions: CLL/SLL
Interventions: DRUG: Lisaftoclax (APG-2575)|DRUG: Acalabrutinib|DRUG: Fludarabine|DRUG: Cyclophosphamide，CTX|DRUG: Rituximab|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part, Phase 1, Single-Dose Study of IL-31 mAb (Anti-Interleukin 31 Monoclonal Antibody); in Healthy Subjects and Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Healthy Subjects and Atopic Dermatitis Subjects
Interventions: BIOLOGICAL: BMS-981164|BIOLOGICAL: Placebo matching with BMS-981164
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation of New Ostomy Appliances
Status: COMPLETED
Conditions: Leakage
Interventions: DEVICE: test product 1: new ostomy base plate with Coloplast as manufacturer|DEVICE: test product 2: new ostomy base plate with Coloplast as manufacturer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Community Health Worker Intervention to Address Adverse Pregnancy Outcomes
Status: NOT_YET_RECRUITING
Conditions: Preeclampsia Postpartum|Adverse Pregnancy Outcomes
Interventions: BEHAVIORAL: usual postpartum care|BEHAVIORAL: usual postpartum care + community health worker intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Evaluate the Safety of the Autologous GrOwnValve Transcatheter Pulmonary Heart Valve
Status: RECRUITING
Conditions: Pulmonary Valve Insufficiency
Interventions: DEVICE: GrOwnValve - novel heart valve replacement approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Two Different Methods of Partial Inflation of Cuff for Facile Insertion of Laryngeal Mask Airway in Adult Patients
Status: COMPLETED
Conditions: General Anesthesia
Interventions: PROCEDURE: The cuff inflation by the resting volume|PROCEDURE: The cuff inflation by half the maximum volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effectiveness of the Aeroneb in Acute Severe Asthma
Status: COMPLETED
Conditions: Asthma Exacerbation
Interventions: DEVICE: Aeroneb nebulizer|DEVICE: Small volume jet nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Direct Coagulation Factor Xa Inhibitor SYHA136 Tablets in Chinese Healthy Volunteers
Status: UNKNOWN
Conditions: Venous Thrombosis
Interventions: DRUG: SYHA136 0.5 mg|DRUG: SYHA136 1 mg|DRUG: SYHA136 2.5 mg|DRUG: SYHA136 5 mg|DRUG: SYHA136 10 mg|DRUG: SYHA136 20 mg|DRUG: SYHA136 35 mg|DRUG: SYHA136 50 mg|DRUG: Placebo matching SYHA136 0.5 mg|DRUG: Placebo matching SYHA136 1 mg|DRUG: Placebo matching SYHA136 2.5 mg|DRUG: Placebo matching SYHA136 5 mg|DRUG: Placebo matching SYHA136 10 mg|DRUG: Placebo matching SYHA136 20 mg|DRUG: Placebo matching SYHA136 35 mg|DRUG: Placebo matching SYHA136 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease|Hypertension
Interventions: BEHAVIORAL: In-Person Patient Education|BEHAVIORAL: Commitment to Change|BEHAVIORAL: Blood pressure monitoring|BEHAVIORAL: Written Patient Education|BEHAVIORAL: Text-based reinforcement for CKD self-management|BEHAVIORAL: Community-based education session, reinforcement for self-management|BEHAVIORAL: Text-based reinforcement for general health self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble Vitamins
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: vegetable oil-based spread and oat-based drink (no brand name available)|DIETARY_SUPPLEMENT: vegetable oil-based spread and oat-based drink (no brand name available)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relationship Between the Functional Movement Screen and Isokinetic Muscle Strength of Knee in Different Sport Branches
Status: COMPLETED
Conditions: Muscle Strength|Sport Injury|Muscle Contraction
Interventions: OTHER: Functional Movement Screen (FMS)|OTHER: Isokinetic Muscle Evulation of Knee Muscles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurology Inpatient Clinical Education Trial
Status: COMPLETED
Conditions: Myasthenia Gravis|Guillain-Barre Syndrome|Multiple Sclerosis|Seizures|Parkinsonism|Meningitis|Encephalitis|Headache|Vestibular Disorder|Spondylosis|Normal Pressure Hydrocephalus
Interventions: BEHAVIORAL: Current standard discharge educational intervention|BEHAVIORAL: Personalized discharge educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of the Action Observation Therapy and Robotic Rehabilitation on the Upper-Limb Motor Function in Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Conventional Rehabilitation|DEVICE: Robotic Rehabilitation (ExoRehab X)|PROCEDURE: Action Observation Therapy (AOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Withdrawal and Clinical Outcome in Patients With Moderate to High Cardiovascular Risk But Without Cardiovascular Disease
Status: NOT_YET_RECRUITING
Conditions: Healthy Participants With Moderate and High Cardiovascular Risk
Interventions: OTHER: Withdrawal of aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of the Oral Platinum Agent Satraplatin in Combination With Weekly Docetaxel
Status: TERMINATED
Conditions: Tumors|Prostate Cancer
Interventions: DRUG: Satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Preoperative Aerobic Exercise Program in Patients With Gastrointestinal Cancer.
Status: UNKNOWN
Conditions: Stomach Neoplasms|Colonic Neoplasms|Rectal Neoplasms|Liver Neoplasm
Interventions: OTHER: Preoperative exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bilateral Ultrasound Guided ESP Block Versus TAP Block on Post-operative Analgesia After Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Post-operative Analgesia
Interventions: PROCEDURE: 1) Ultrasound guided Erector spinae block|PROCEDURE: Ultrasound guided transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral and Topical Sea Buckthorn Oil Treatments on Skin Aging
Status: UNKNOWN
Conditions: Skin Aging
Interventions: OTHER: Omega7 Sea Buckthorn Oil Cream|OTHER: Base cream|DIETARY_SUPPLEMENT: SBA24 Sea Buckthorn Oil Capsule|DIETARY_SUPPLEMENT: SBA24 Sea Buckthorn Oil Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
Status: COMPLETED
Conditions: Transient Ischemic Attack|Non-disabling Stroke
Interventions: BEHAVIORAL: PREVENT program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FALCON: a Multicenter Randomized Controlled Trial
Status: UNKNOWN
Conditions: Cholecystolithiasis|Cholecystitis
Interventions: DEVICE: Laparoscopic Fluorescence Imaging System (Karl Storz)|OTHER: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Systems Analysis and Improvement Approach for the Hypertension Care Cascade
Status: RECRUITING
Conditions: HIV/AIDS|Hypertension
Interventions: OTHER: Systems Analysis and Improvement Approach for Hypertension Screening and Treatment Optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Benign and Malignant Biliary Tract Diseases
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Diseases|Gallbladder Cancer|Extrahepatic Bile Duct Cancer|Intrahepatic Cholangiocarcinoma|Biliary Tract Neoplasms|Gall Stone
Interventions: OTHER: no interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Monitoring and Management of Chemotherapy Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: OTHER: Symptom Care at Home with NP follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial II of Lung Protection With Azithromycin in the Preterm Infant
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mifepristone in Refractory Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Mifepristone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Angiogenic and EGFR Blockade With Curative Chemoradiation for Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Pharynx Cancer
Interventions: RADIATION: Chemoradiotherapy|DRUG: Cisplatin|DRUG: Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Addition to Autologous Transplantation With BEAM for Patients With Lymphoid Malignancies
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 2 Techniques of Apheresis to Desensitize ABO Incompatible Kidney Transplant Candidates
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: Large volume specific immunoadsorption|PROCEDURE: Double Filtration Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Intramuscular Midazolam Compared to Buccal Midazolam in Pediatric Seizures
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Buccal midazolam|DRUG: Intramuscular midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old
Status: COMPLETED
Conditions: Pyelonephritis
Interventions: DRUG: antibiotic|DRUG: antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compared Unidirectional Valve Apparatus and Occluding the Non-ventilated Endobronchial Lumen for Lung Collapse.
Status: NOT_YET_RECRUITING
Conditions: Video-assisted Thoracoscopic Surgery|One-Lung Ventilation
Interventions: PROCEDURE: unidirectional valve apparatus|PROCEDURE: occluding the non-ventilated endobronchial lumen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Value of Using Colostrum Supplements on the Physical Performance and Cognitive Function in Healthy Subjects and Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Colostrum Capsule 500 mg (Colostrum® 500 mg Veg Capsules, nowfoods®, Illinois, USA)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interrupted Oblique Intradermal Suture Versus Conventional Interrupted Intradermal Suture
Status: COMPLETED
Conditions: Surgery
Interventions: PROCEDURE: Oblique Intradermal Suture|PROCEDURE: Intradermal Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Orifice Transluminal Endoscopic Surgery for Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: PROCEDURE: natural orifice specimen extraction|PROCEDURE: Laparoendoscopic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxycodone in Combination With Parathoracic Nerve Block is Used for Postoperative Analgesia in Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Oxycodone
Interventions: DRUG: Oxycodone 1mg/kg|DRUG: Oxycodone 1.5mg/kg|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Incontinence|Pelvic Floor Disorders|Gynecologic Disease|Post-Op Infection|Surgical Site Infection|Urinary Tract Infections
Interventions: DRUG: Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Catumaxomab for Treatment of Peritoneal Carcinomatosis in Patients With Gastric Adenocarcinomas
Status: COMPLETED
Conditions: Gastric Adenocarcinoma With Peritoneal Carcinomatosis|Siewert Type II Adenocarcinoma of Esophagogastric Junction With Peritoneal Carcinomatosis|Siewert Type III Adenocarcinoma of Esophagogastric Junction With Peritoneal Carcinomatosis
Interventions: DRUG: catumaxomab, Fluorouracil, leucovorin, oxaliplatin, docetaxel|DRUG: Fluorouracil, leucovorin, oxaliplatin, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain
Status: COMPLETED
Conditions: Cancer|Pain|Constipation
Interventions: DRUG: Oxycodone|DRUG: Oxycodone/Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Helping Relationships From Significant Others on Healthy Lifestyle and Quality of Life Among Patients With Chronic Kidney Disease: A Longitudinal Study
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: The helping relationships intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Education and Counseling Program on Patients With CIEDs and Low HL
Status: RECRUITING
Conditions: Arrhythmias, Cardiac|Heart Failure|Health Knowledge, Attitudes, Practice
Interventions: OTHER: Education and Counseling Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bortezomib and Vorinostat in Treating Patients With Multiple Myeloma Who Have Undergone Autologous Stem Cell Transplant
Status: COMPLETED
Conditions: DS Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of HepCure Toolkit to Improve Harvoni Adherence
Status: COMPLETED
Conditions: Hepatitis C|Medication Adherence
Interventions: OTHER: HepCure ToolKit|DEVICE: AdhereTech Active Features|OTHER: AdhereTech Passive Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Zoledronic Acid on Bone Density in Liver Transplant Patients
Status: COMPLETED
Conditions: Osteoporosis|Liver Transplantation|Fractures
Interventions: DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Code of Respect (X-CoRe): Trial of a Multi-level Sexual Assault and Sexual Harassment Prevention Intervention for Active Duty Airmen
Status: NOT_YET_RECRUITING
Conditions: Sexual Assault|Sexual Harassment
Interventions: BEHAVIORAL: Junior Enlisted Component|BEHAVIORAL: Leadership Component|BEHAVIORAL: Social Marketing Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial
Status: COMPLETED
Conditions: Femur Fracture
Interventions: DRUG: 0.5% ropivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Combination With FOLFIRI in Third or Fourth Line of Treatment of Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Masitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Treatment for Depressed Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral treatment (CBT)|BEHAVIORAL: CBT+Behavioral Activation (BA)|BEHAVIORAL: CBT+BA+ Contingency Management (CM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Supplement and Exercise Training for the Treatment of Malnutrition and Sarcopenia Risk in Older Adults
Status: RECRUITING
Conditions: Sarcopenia|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Fortimel Advanced, Nutricia|OTHER: Resistance Exercise programme|OTHER: Dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of NST-1024 Versus Placebo in Subjects With Hypertriglyceridemia
Status: RECRUITING
Conditions: High Triglycerides
Interventions: DRUG: NST-1024|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Single Chemotherapy Administration on Skeletal Muscle of Breast Cancer Patients: Comparison of Paclitaxel vs Paclitaxel + Trastuzumab vs Paclitaxel + Carboplatine: the PROTECT-06 Bis Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: First Assessment|OTHER: Second Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Sinol or Sinol-M nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral / Oral Trimethoprim - Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia in AIDS
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Telehealth-Based ASD Assessments and Supports on Child and Caregiver Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Help is in Your Hands
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A PK Study to Assess the Drug-drug Interaction of a Strong CYP2C8 Inhibitor on Adagrasib
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Treatment A|DRUG: Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Trial of Pangramin SLIT HDM-mix in Subjects With House Dust Mite Induced Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Pangramin SLIT HDM mix.|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Childhood Hearing Loss in Rural Alaska Through a Preschool Screening and Referral Process Using Mobile Health and Telemedicine
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Current Primary Care Referral Process|OTHER: Telemedicine Referral Process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Added Value of Hybrid Functional Anatomical Imaging PET-CT and SPECT-CT in Patients Treated With Y-90 SIRT for Liver Malignancies
Status: COMPLETED
Conditions: Primary Liver Tumor, Metastatic Liver
Interventions: OTHER: Tc99-MAA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of HRS-8427 in the Treatment of Adults With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
Status: NOT_YET_RECRUITING
Conditions: Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP)
Interventions: DRUG: HRS-8427|DRUG: Imipenem and Cilastatin Sodium|DRUG: HRS-8427 placebo|DRUG: Imipenem and Cilastatin Sodium placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study to Evaluate Immunogenicity of Three Different Dose Levels of the IMVAMUNE (MVA-BN) Smallpox Vaccine.
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: IMVAMUNE (MVA-BN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION