pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment Adherence Enhancement in Bipolar Disorder
Status: COMPLETED
Conditions: Treatment Noncompliance|Bipolar Disorder
Interventions: BEHAVIORAL: Customized Adherence Enhancement (CAE)|BEHAVIORAL: broadly-directed, non-individualized education (EDU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Calorie High Protein Nutrition Supplementation in Advanced Heart Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: Calorie protein supplement|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Status: RECRUITING
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Etelcalcetide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Cilnidipine/Valsartan Combination Tablet With Coadministration of Cilnidipine and Valsartan
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: cinidipine, valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment for Acute Basilar Artery Occlusion
Status: COMPLETED
Conditions: Basilar Artery Occlusion|Acute Cerebrovascular Accident|Stroke Due to Basilar Artery Occlusion
Interventions: PROCEDURE: endovascular treatment|OTHER: best medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Pain Relief After Replacement of the Knee
Status: TERMINATED
Conditions: Acute Postoperative Pain
Interventions: DRUG: ATX-101|DRUG: ATX-101|DRUG: bupivacaine hydrochloride without epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab With High-dose Ibrutinib for the Treatment of Patients With Chronic Lymphocytic Leukemia With Progressive Disease on Single Agent Ibrutinib.
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: ibrutinib|DRUG: obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: OTHER: None-observational|PROCEDURE: Magnetic Resonance Imaging (MRI)|OTHER: Multimodal Automated Sensory Testing System|OTHER: Auditory Sensitivity Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5
Status: COMPLETED
Conditions: End-Stage Renal Disease|Stage 5 Chronic Kidney Disease
Interventions: DRUG: Telavancin|PROCEDURE: Pharmacokinetic Blood Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: S0019 Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction With SVF Derived MSC in Living-related Kidney Transplantation
Status: UNKNOWN
Conditions: Living-relative Kidney Transplantation
Interventions: PROCEDURE: SVF-MSC induction|DRUG: Basiliximab induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hangover and Residual Zopiclone Effect on Spatial Perception
Status: UNKNOWN
Conditions: Healthy|Alcohol Drinking
Interventions: DRUG: Zopiclone|BEHAVIORAL: hangover|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lacosamide infusion|DRUG: Lacosamide oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Compare Two Tablet Forms of Tafamidis in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tafamidis free acid tablet (Test)|DRUG: Tafamidis free acid tablet (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: 5-13C-Glutamine|OTHER: Bone marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhaled Extra-fine Hydrofluoalkane-beclomethasone (QVAR) in Premature Infants With Bronchopulmonary Dysplasia (BPD)
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Inhaled extra-fine hydrofluoalkane-beclomethasone (QVAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Behavioural Intervention to Increase Breast Cancer Screening Rates Among Members of the Public
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasm Female
Interventions: BEHAVIORAL: Standard Health Communication Intervention|BEHAVIORAL: Behavioural Change Health Communication Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Intensified Chemo-immuno-radiotherapy With Durvalumab for Stage III Non-Small Cell Lung Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasms
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilumab Step-down Strategy to Maintain Remission in Adult and Adolescents Patients With Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis|Eczema, Atopic
Interventions: DRUG: Dupilumab step-down
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of HMB on Skeletal Muscle Wasting in Early Critical Illness
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: HMB|OTHER: Lactose (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Aerobic Exercise in Patients With Post COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: High-intensity interval aerobic exercise training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Breast Cancer|Endometrial Cancer
Interventions: DIETARY_SUPPLEMENT: Genistein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)
Status: COMPLETED
Conditions: Malnutrition|Manihot Species Poisoning
Interventions: BEHAVIORAL: Wetting method (WTM)|BEHAVIORAL: Mediational Intervention for Sensitizing Caregivers (MISC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect Evaluation of Continuous Nursing Intervention in Patients With Type 2 Diabetic Retinopathy
Status: COMPLETED
Conditions: Type 2 Diabetic Retinopathy
Interventions: BEHAVIORAL: A continuous nursing intervention group was established.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BiPhasic Cartilage Repair Implant (BiCRI) IDE Clinical Trial - Taiwan
Status: COMPLETED
Conditions: Chondral or Osteochondral Lesion of Medial Femoral Condyle|Chondral or Osteochondral Lesion of Lateral Femoral Condyle|Chondral or Osteochondral Lesion of Trochlea
Interventions: DEVICE: BiPhasic Cartilage Repair Implant|PROCEDURE: Marrow Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Balneotherapy in Older Adults With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain|Older Adults|Health Resort Medicine|Quality of Life
Interventions: PROCEDURE: Physiotherapy modalities|PROCEDURE: Balneotherapy modalities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: indinavir sulfate|DRUG: nelfinavir mesylate|DRUG: paclitaxel|DRUG: ritonavir|DRUG: saquinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of Cura-100 in Subjects With Rheumatoid Arthritis and Osteoarthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Osteoarthritis
Interventions: DRUG: Cura-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Eltrombopag in Chinese Refractory or Relapsed Severe Aplastic Anemia (SAA) Subjects.
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: Eltrombopag 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diffusion-weighted Imaging Magnetic Resonance for Assessing Liver Fibrosis
Status: COMPLETED
Conditions: Fibrosis, Liver
Interventions: DEVICE: Diffusion-weighted magnetic resonance imaging (DW-MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal Feeding Tube Dwell Time in VLBW Infants to Reduce Feeding Tube Contamination
Status: COMPLETED
Conditions: Infection
Interventions: DEVICE: Feeding tube dwell time of 48 hours|DEVICE: Feeding tube dwell time of 7 day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Effect of Intravenous Lidocaine Infusion on Postoperative Pain Treatment and Bowel Function in Robotic Bowel Surgery
Status: COMPLETED
Conditions: Opioid Use
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Study of Darbepoetin Alfa in Partial Correction of Anemia in Chinese With Diabetic Nephropathy
Status: TERMINATED
Conditions: Diabetes Mellitus|Chronic Kidney Disease|Anemia
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SPACER Trial - Repair of Tricuspid Valve Regurgitation Using the Edwards TricuSPid TrAnsCatheter REpaiR System
Status: COMPLETED
Conditions: Tricuspid Valve Regurgitation
Interventions: DEVICE: EW Tricuspid Transcatheter Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Role of Liquid Based Cytology (LBC) for Diagnosis and Characterization of Biliopancreatic Tumor s Compared With Standard Cytology and On-site Evaluation.
Status: UNKNOWN
Conditions: Pancreatobiliary-Type Carcinoma
Interventions: DIAGNOSTIC_TEST: Liquid based cytology|DIAGNOSTIC_TEST: Conventional cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
Status: RECRUITING
Conditions: Physical Activity|Exercise|Heart Diseases|Diabetes Mellitus|Physical Inactivity
Interventions: BEHAVIORAL: Smart Walk|BEHAVIORAL: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open Label to Study to Evaluate Effect of Alfilbercept on Patients With (FVPED) Fibrovascular Pigment Epithelial Detachment
Status: WITHDRAWN
Conditions: Fibrovascular Pigment Epithelial Detachment
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of TC-5619 in Adults With Attention Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: TC-5619-238|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Vestibular Rehabilitation Therapy Supported With Virtual Reality in the Elderly Patients With Dizziness
Status: UNKNOWN
Conditions: Dizziness|Vestibular Rehabilitation|Virtual Reality
Interventions: OTHER: Vestibular Rehabilitation supported with Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagal Nerve Stimulation to Prevent Tachyarrhythmias in Patients Early Following Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction|Tachyarrhythmia
Interventions: DEVICE: Parasym device (active, current (mA) < discomfort threshold)|DEVICE: Parasym device (sham, current (mA) = 0)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Inactivated and Live-attenuated HAV Vaccine Among Thai Healthy Children and Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: HAV|Hepatitis A|Hep A|Vaccine-Preventable Diseases
Interventions: BIOLOGICAL: Mevac-A vaccine|BIOLOGICAL: Havrix 720 Junior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Letrozole, Palbociclib, and Onapristone ER in People With Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer|Unresectable Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Palbociclib|DRUG: Onapristone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cabazitaxel in Pediatric Patients With Refractory Solid Tumors Including Central Nervous System Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumor - Malignant Nervous System Neoplasm
Interventions: DRUG: Cabazitaxel (XRP6258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Midazolam in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: Telotristat etiprate|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy (HBOT) for Chronic Diabetic Lower Limb Ulcers
Status: COMPLETED
Conditions: Diabetes Mellitus|Chronic Ulcers of the Lower Limb
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy|PROCEDURE: Placebo Hyperbaric Oxygen Chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diosmiplex (Vasculera®) in Primary and Secondary Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Disease
Interventions: OTHER: placebo|DIETARY_SUPPLEMENT: diosmiplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of AZD3199 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: AZD3199|DRUG: formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study on the Diagnostic Value Comparison of 18F-FAPI-04 PET/CT and PET/MR in Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DIAGNOSTIC_TEST: The clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy in Treating Women Undergoing Lumpectomy for Stage I or Stage IIA Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: hypofractionated radiation therapy|RADIATION: intraoperative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Status: RECRUITING
Conditions: ACL Tear|Opioid Misuse|Pain|Anxiety
Interventions: DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Broccoli Sprout Extract in Treating Patients With Breast Cancer
Status: COMPLETED
Conditions: Ductal Breast Carcinoma|Ductal Breast Carcinoma In Situ|Estrogen Receptor Negative|Estrogen Receptor Positive|Invasive Breast Carcinoma|Lobular Breast Carcinoma|Postmenopausal|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer
Interventions: DRUG: Broccoli Sprout Extract|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
Status: RECRUITING
Conditions: Myotonic Dystrophy|Facioscapulohumeral Muscular Dystrophy|Muscular Dystrophy|Myotonic Dystrophy Type 1|Myotonic Dystrophy Type 2|Congenital Myotonic Dystrophy|PROMM (Proximal Myotonic Myopathy)|Steinert's Disease|Myotonic Muscular Dystrophy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between PEEK With Platelet-rich Fibrin and PEEK Alone in Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Maxillary Sinus
Interventions: OTHER: platelet rich fibrin|OTHER: Polyether ether ketone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Interventions and Cutaneous T Cell Lymphoma (CTCL)
Status: TERMINATED
Conditions: Anxiety|Quality of Life
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-inferiority Bioavailabilty Study of 3 Silicon-rich Supplements
Status: COMPLETED
Conditions: Absorption; Disorder
Interventions: DIETARY_SUPPLEMENT: Prod1|DIETARY_SUPPLEMENT: Prod2|DIETARY_SUPPLEMENT: Prod3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Psychoeducation and Support Protocol by Phone in the Aid of Caregivers of Patients With Dementia.
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: Telesupport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluconazole|DRUG: Diflucan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lumbar Proprioception in Patients With Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Spinal Stenosis Lumbar
Interventions: OTHER: Reposition error (RE), pain at target positions of RE and flexibility of the TLF were assesed with iphone tiltmeter app, VAS and goniometric platform, respectively.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Laughter Yoga on Hope and School Burnout
Status: COMPLETED
Conditions: Laughter Therapy|Laughter Yoga|Hope|School Burnout
Interventions: BEHAVIORAL: Laughter yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Instinct™ Ultrasound Device Safety, Efficacy and Usability
Status: COMPLETED
Conditions: Ultrasonography, Prenatal
Interventions: DEVICE: Obstetrics Ultrasound (non invasive)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acceptance and Commitment Therapy for Smoking Cessation in the Primary Care Setting
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Control|BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
Status: TERMINATED
Conditions: Wound Infection
Interventions: OTHER: povidone-iodine solution|OTHER: chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stanford Coronary Risk Intervention Project (SCRIP)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Arteriosclerosis|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: BEHAVIORAL: smoking cessation|BEHAVIORAL: diet, reducing|BEHAVIORAL: exercise|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Metastatic Melanoma|Skin Cancer
Interventions: DRUG: temozolomide|DRUG: ABT-888|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Performance of SurgiClot® in the Treatment of Cancellous Bone Bleeding
Status: COMPLETED
Conditions: Cancellous Bone Bleeding
Interventions: DEVICE: SurgiClot haemostatic dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study 23G Versus 27G Vitrectomy
Status: COMPLETED
Conditions: Vitreoretinal Surgery
Interventions: DEVICE: Vitrectomy (23G gauge needle)|DEVICE: Vitrectomy (27G gauge needle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Metformin hydrochloride|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Trial of Nerve-Spring Radical Hysterectomy vs. Radical Hysterectomy for Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: Nerve-spring radical hysterectomy|PROCEDURE: radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Oral Bioavailability of GABA From Tomatoes
Status: COMPLETED
Conditions: GABA Plasmakinetics
Interventions: DIETARY_SUPPLEMENT: Tomato|DIETARY_SUPPLEMENT: GABA supplement|DIETARY_SUPPLEMENT: Glutamate supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Immunogenicity Trial of IHV01
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: 300 ug FLSC vaccine|BIOLOGICAL: 150 ug FLSC vaccine|BIOLOGICAL: 75 ug FLSC vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass (RYGB)|BEHAVIORAL: Caloric Restriction|DRUG: Exendin-9,39|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amitriptyline Regarding Nimesulide in Acute Idiopathic Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: DRUG: amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin Versus Vildagliptin in CAD Patients With T2DM
Status: RECRUITING
Conditions: Coronary Artery Disease|Type 2 Diabetes
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Vildagliptin 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic and Prebiotic Supplementation in Elite Athletes With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DIETARY_SUPPLEMENT: Multistrain probiotic preparation|DIETARY_SUPPLEMENT: Oat Bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial for the Treatment of Acute Hepatitis C for 8 Weeks With Sofosbuvir/Velpatasvir
Status: COMPLETED
Conditions: Hepatitis C|Acute Hepatitis C
Interventions: DRUG: Sofosbuvir and Velpatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Elbasvir (MK-8742) + Grazoprevir (MK-5172) in Treatment-Naïve/Treatment-Experienced (TN/TE) French Participants With Hepatitis C Virus (HCV) Genotype 4 (GT4) Infection (MK-5172-096)
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV) Infection
Interventions: DRUG: EBR/GZR (50 mg/100 mg) FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Vena Jugularis Interna Catheterization Lateral Approach Short Axis in - Plane Technique
Status: COMPLETED
Conditions: Central Vein Catheter
Interventions: PROCEDURE: Ultrasound Guided Lateral Approach Catheterization of Jugular Internal Vein|PROCEDURE: Ultrasound Guided Conventional Approach Catheterization of Jugular Internal Vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Balanced Placebo Design With Varenicline: Pharmacological and Expectancy Effects on Medication Adherence
Status: COMPLETED
Conditions: Medication Adherence
Interventions: DRUG: Varenicline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ARVAC - A New Recombinant Coronavirus Disease 2019 (COVID-19) Vaccine
Status: COMPLETED
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: ARVAC-CG vaccine (recombinant protein vaccine against SARS-CoV-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: BIOLOGICAL: Bronchial basal cells (BBCs)|PROCEDURE: Bronchoscopic airway clearance treatment （B-ACT）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Effects on Post-operative Pain and Lumbar Fusion
Status: NOT_YET_RECRUITING
Conditions: Spinal Fusion
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of High-risk Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Camrelizumab in Combination With Neoadjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin for Dukes C and High Risk Dukes B Colorectal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: placebo|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Morbidities, Endpoints and Reaching Targets in Diabetic Patients Managed by a Diabetes Specialist Team
Status: UNKNOWN
Conditions: Diabetes|Obesity
Interventions: OTHER: EMERALD|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)
Status: COMPLETED
Conditions: Glioblastoma
Interventions: PROCEDURE: Primary surgical treatment|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: DRUG: Fluoxetine|COMBINATION_PRODUCT: fluoxetine + cognitive-behavioral treatment（CBT）|DRUG: fluoxetine + Amfebutamone|COMBINATION_PRODUCT: physical treatment+fluoxetine+amfebutamone|DRUG: Fluvoxamine|DRUG: Lithium+fluvoxamine|COMBINATION_PRODUCT: fluvoxamine + lithium + physical therapy|COMBINATION_PRODUCT: Cognitive behavior treatment +fluvoxamine|DRUG: Mirtazapine/SNRIs|COMBINATION_PRODUCT: mirtazapine+ Cognitive behavior treatment|DRUG: mirtazapine + SNRIs|COMBINATION_PRODUCT: mirtazapine + SNRIs + physical therapy|OTHER: TAU(treat as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effect of Prolotherapy and Paraffin Waxes for Hand Osteoarthritis
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: OTHER: Paraffin wax|DRUG: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Hoarding Disorder|Hoarding|Clutter
Interventions: BEHAVIORAL: Facilitated group therapy with behavioral practice; 18 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOACs Use in AF or VTE (SUNSHINE Registry)
Status: RECRUITING
Conditions: Atrial Fibrillation|Venous Thromboembolism|Oral Anticoagulant
Interventions: OTHER: Patients with Atrial Fibrillation (AF) or venous thromboembolism (VTE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Train of Four Motor Point Stimulation and Monitoring
Status: WITHDRAWN
Conditions: Observation of Neuromuscular Block
Interventions: DEVICE: Neuromuscular Block Aid|DEVICE: Standard of Care: Microstim Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Krio in Children and Adults With Epilepsy
Status: WITHDRAWN
Conditions: Ketogenic Dieting|Epilepsy|Glucose Transporter Type 1 Deficiency Syndrome
Interventions: DIETARY_SUPPLEMENT: Krio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of HRO350 in Patients With Mild-to-moderate Psoriasis (the 'HeROPA' Study).
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: HRO350|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty
Status: COMPLETED
Conditions: Deformity of Nasal Cartilage
Interventions: DRUG: Restylane-L® Filler injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B
Status: WITHDRAWN
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: hepatitis B immune globulin (HBIg)|DRUG: Pegylated interferon alfa (pegIFN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the BioMed rTSST-1 Variant Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Toxic Shock Syndrome
Interventions: BIOLOGICAL: rTSST-1v
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Pharmacodynamic Effects on Segmental Endotoxin Induced Inflammatory Response of BI 1026706 Versus Placebo
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1026706|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Selective PI3K-Beta Inhibitor GSK2636771 in Combination With Pembrolizumab in Patients With Metastatic Melanoma and PTEN Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma and Other Malignant Neoplasms of Skin|Metastatic Melanoma
Interventions: DRUG: GSK2636771|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Viscous Budesonide in Anastomotic Stricture After Esophageal Atresia Repair (OVB in EA)
Status: UNKNOWN
Conditions: Esophageal Atresia|Anastomotic Stenosis
Interventions: DRUG: Budesonide Oral|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Males
Status: COMPLETED
Conditions: Healthy|Male
Interventions: DRUG: Zanubrutinib|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Develop Predictive and Prognostic Tools for Optimizing Therapy With Bevacizumab Frontline Cancer Therapy in Participants With HER 2-Negative Aggressive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: hUC Mesenchymal Stem Cells (19#iSCLife®-CSD) Therapy for Patients With Healing Poor After Uterus Injury
Status: COMPLETED
Conditions: Uterus; Injury
Interventions: PROCEDURE: intrauterine injection|BIOLOGICAL: human umbilical cord mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CareFUL Prevention Trial
Status: COMPLETED
Conditions: Plantar Ulcer|Diabetes|Neuropathy Causing Loss of Protective Sensation
Interventions: DEVICE: TrueContour® Insole|DEVICE: Current standard of care insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Oily Fish and Poultry on Children's Cardiometabolic Health and Cognitive Function
Status: COMPLETED
Conditions: Cardiometabolic Health|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Oily fish|DIETARY_SUPPLEMENT: Poultry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Erlotinib With Concurrent Radiotherapy in Unresectable NSCLC With Activating Mutation of EGFR in Exon 19 or 21
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Erlotinib w Concurrent Radiotherapy|OTHER: etoposide/cis-platin (EP) w Concurrent Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RADVAX™: A STRATIFIED PHASE I/II DOSE ESCALATION TRIAL OF HYPOFRACTIONATED RADIOTHERAPY FOLLOWED BY IPILIMUMAB IN METASTATIC MELANOMA
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Ipilimumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Melatonin to Improve Sleep in Children With Epilepsy and Neurodevelopmental Disabilities
Status: COMPLETED
Conditions: Epilepsy|Insomnia|Developmental Disability
Interventions: DRUG: Fast Release Melatonin (FR MLT)|DRUG: Fast Release Placebo|DRUG: Timed Release Melatonin (TR MLT)|DRUG: Timed Release Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rifaximin to Prevent Recurrent HCV-Related Fibrosis After Liver Transplant
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Lorlatinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Booster Study of COVID-19 Protein Subunit Recombinant Vaccine
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 subunit protein recombinant vaccine|BIOLOGICAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Animal Assisted Mindfulness Intervention (AAMI) for Patients With Acquired Brain Injury
Status: COMPLETED
Conditions: Acquired Brain Injury
Interventions: BEHAVIORAL: Animal assisted mindfulness based intervention|BEHAVIORAL: Anti-stress program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|CRC|KRAS/NRAS Mutation
Interventions: DRUG: Onvansertib|DRUG: FOLFIRI|DRUG: Bevacizumab|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assistive Soft Robotic Glove Intervention Using Brain-Computer Interface for Elderly Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: BCI Robot Assisted Hand Therapy|DEVICE: CPM Robot Assisted Hand Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver Cancer
Status: SUSPENDED
Conditions: Resectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Capecitabine|DEVICE: Selective Internal Radiotherapy (SIRT)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: ST-01|DRUG: 1% Lidocaine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adujvant CT+CRT vs Adujvant CT After D2 Resection for Locally Advanced Proximal Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: RADIATION: Adjuvant Chemoradiotherapy|DRUG: Adjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: E2007|DRUG: E2007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Bihemispheric Transcranial Direct Current Stimulation After Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Bihemispheric transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bivalirudin Versus Heparin for Systemic Anticoagulation in Extracorporeal Membrane Oxygenation
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation Complication|Anticoagulants
Interventions: DRUG: Bivalirudin|DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MBL Around Implants Placed in Crestal or Subcrestal Positions: a RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw, Edentulous|Partial Edentulism
Interventions: PROCEDURE: Crestal|PROCEDURE: Subcrestal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Neuropathic Pain
Interventions: BEHAVIORAL: Cognitive Multisensory Therapy|OTHER: Usual Care|BEHAVIORAL: Clinical Assessment|BEHAVIORAL: Magnetic Resonance Imaging (MRI)|OTHER: OPTIONAL: blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT