pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By Chemotherapy
Status: WITHDRAWN
Conditions: Infection|Neutropenia|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: daptomycin|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Belzutifan|BIOLOGICAL: Pembrolizumab/Quavonlimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study the Impact of Hirsutella Sinensis Nutrient Supplements Has on Improving Muscle Health and Metabolism in Elderly
Status: UNKNOWN
Conditions: Sarcopenia|Old Age; Debility|Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Hirsutella Sinensis Nutrient Supplements|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Mitral Repair for Functional Mitral Regurgitation
Status: COMPLETED
Conditions: Cardiomyopathy|Cardiovascular Diseases|Congestive Heart Failure|Coronary Artery Disease|Heart Disease|Valvular Heart Disease|Mitral Valve Disease
Interventions: PROCEDURE: Undersizing Mitral Annuloplasty|PROCEDURE: Papillary Muscle Approximation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Probiotics on Glycemic Control of Women With Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Femina II|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of a Neural Interface and a Neurostimulation in the Rehabilitation of Upper Limb Movement Impairments.
Status: UNKNOWN
Conditions: Stroke|Spinal Cord Injuries
Interventions: DEVICE: VIBRAINT RehUp robotic orthosis|PROCEDURE: tSCS during the exercise|PROCEDURE: tSCS prior to the exercise|DEVICE: Neostim-5|PROCEDURE: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine in Chinese Patients With Young Onset Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Biogenetic explanation and endocrinologist intensive managment|OTHER: Usual care management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Satisfaction of Patients With the Chosen Method of Inhibition of Lactation
Status: UNKNOWN
Conditions: Lactation Suppressed
Interventions: DRUG: Bromocriptine|DRUG: Cabergoline|OTHER: Natural methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Dexmedetomidine on Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Lung Cancer|Video-assisted Thoracoscopic Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Role of Nutritional Support in Idiopathic Male Infertility
Status: UNKNOWN
Conditions: Infertility, Male
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement with L-carnitine (FertilHom)|DIETARY_SUPPLEMENT: Control Dietary Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder
Status: RECRUITING
Conditions: Neurodevelopmental Disorders|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Early intervention|BEHAVIORAL: Active monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use
Status: NOT_YET_RECRUITING
Conditions: Electronic Cigarette Use|Endothelial Dysfunction|Inflammation
Interventions: DRUG: Placebo|DRUG: Salsalate 750 MG Oral Tablet [DISALCID]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraoperative Sufentanil and Chronic Postsurgical Pain in Non-major Scheduled Abdominal Surgery
Status: RECRUITING
Conditions: Chronic Postsurgical Pain|Chronic Pain|Abdominal Surgery|Sufentanil|Risk Factors
Interventions: OTHER: phone interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Water and Land-based Exercise for Children With Post COVID-19 Condition
Status: COMPLETED
Conditions: COVID-19|Children, Only|Lung Function Decreased|Quality of Life
Interventions: OTHER: Water-based exercise|OTHER: Land-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of High-flow Nasal Cannula Oxygen and Jet Ventilation Techniques
Status: COMPLETED
Conditions: Oxygen|pH|End-tidal Carbon Dioxide
Interventions: PROCEDURE: oxygenization techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Treatment Plan of Neurological Physiotherapy in Conjunction With Ultrasound-guided Ultrasound-guided Dry Needling in Stroke Patients.
Status: COMPLETED
Conditions: Neurological Disorder
Interventions: DEVICE: dry needling|OTHER: convencional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Finerenone (BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Stroke Secondary Prevention Trial
Status: WITHDRAWN
Conditions: Stroke|Transient Ischemic Attack
Interventions: DRUG: Folic Acid|DRUG: Vitamin B6|DRUG: Vitamin B12|DRUG: placebo|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of High and Low Frequency TENS on Sympathetic Skin Response and Skin Temperature
Status: COMPLETED
Conditions: Effects of TENS on Sympathetic Skin Response
Interventions: DEVICE: transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Microvascular Invasion for Guiding Treatment of Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Radiomics|Hepatocellular Carcinoma (HCC)|Transcatheter Arterial Chemoembolization (TACE)|Microvascular Invasion (MVI)|Multi-kinase Inhibitors (MKI)
Interventions: DRUG: Sorafenib|DRUG: Lenvatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Growth Hormone Co-treatment Within a GnRH Antagonist Protocol in Patients With Poor Ovarian Response
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Growth hormone/HPuFSH/GnRH antagonist|DRUG: HPuFSH/GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality Assurance of Administering Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD) - QUMEA
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
Status: RECRUITING
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Invasive Breast Carcinoma|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions: DRUG: Docetaxel|PROCEDURE: Lumpectomy|PROCEDURE: Mastectomy|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|BIOLOGICAL: Pertuzumab|RADIATION: Radiation Therapy|BIOLOGICAL: Trastuzumab|BIOLOGICAL: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: FALCON Trial Testing Measures to Reduce Surgical Site Infection
Status: UNKNOWN
Conditions: Abdominal Surgery|Surgical Site Infection
Interventions: DRUG: 2% chlorhexidine + non-coated suture|DRUG: 2% chlorhexidine + coated suture|DRUG: 10%povidone-iodine + non-coated suture|DRUG: 10%povidone-iodine + coated suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gatorade/Miralax With or Without Bisacodyl Versus NuLytely for Colonoscopy Preparation
Status: COMPLETED
Conditions: Preparation for Colonoscopy
Interventions: DRUG: Gatorade/Miralax|DRUG: NuLytely|DRUG: Bisacodyl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ulcer Prevention Study in Post Gastric Bypass Patients
Status: COMPLETED
Conditions: Marginal Ulcers
Interventions: DRUG: Omeprazole|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tarceva/Rapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 (NF1)
Status: COMPLETED
Conditions: Low-grade Gliomas
Interventions: DRUG: Tarceva and Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravitreal Long Acting Dexamethasone Implant, Ozurdex in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Macular Edema, Cystoid|Vision Disorders|Clinically Significant Macular Edema
Interventions: DRUG: long acting intravitreal dexamethasone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of D-dimer Combined With Other Thrombus Molecular Markers in Risk Assessment of VTE in Hospitalized Patients
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolic Disease
Interventions: OTHER: Venous blood was collected from patients under fasting state to detect the level of thrombus molecular markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RN1001(Avotermin) in Scar Improvement Following Breast Augmentation
Status: COMPLETED
Conditions: Mammaplasty|Cicatrix
Interventions: DRUG: Avotermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-in-human Study to Assess the Safety and Pharmacokinetics of LML134 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LML134|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Toripalimab for Unresectable HCC With Portal Vein Tumor Thrombus
Status: UNKNOWN
Conditions: Unresectable Hepatocellular Cancer|Portal Vein Tumor Thrombus
Interventions: DRUG: sorafenib; toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Practitioner and Instructional Set on Subject Perceptions and Expectations of Cervical Spine Manipulation
Status: UNKNOWN
Conditions: Neck Pain
Interventions: PROCEDURE: Cervical spine manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation Enhance Post-stroke Walking Survivors and Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Cerebral Vascular Accident
Interventions: COMBINATION_PRODUCT: anodal transcranial direct current stimulation (a-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyroablation for Pulmonary Vein Isolation Alone in Patients With Early Persistent AF Assessed by Continuous Monitoring
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation, Persistent
Interventions: PROCEDURE: cryoballoon ablation|DEVICE: implantable loop recorder insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Dementia With Lewy Bodies|MSA - Multiple System Atrophy|Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: [18F]-MFBG PET CT|DIAGNOSTIC_TEST: [18F]-FE-PE2I PET CT or PET MRI|DIAGNOSTIC_TEST: [123I]-MIBG SPECT CT|DIAGNOSTIC_TEST: [18F]-MFBG PET dosimetry scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of AyuFlex® Supplementation on Joint Health
Status: COMPLETED
Conditions: Arthralgia
Interventions: DIETARY_SUPPLEMENT: AyuFlex|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pawsitive Impacts of Therapy Dog Visits
Status: COMPLETED
Conditions: Pain|Pain, Acute|Pain, Chronic|Pain, Intractable
Interventions: BEHAVIORAL: Therapy Dog Team Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of Soluble Fiber for Asthma
Status: RECRUITING
Conditions: Asthma in Children
Interventions: DRUG: NOVELOSETM 3490
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Valves
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Emphysema
Interventions: DEVICE: Intra-bronchial valve and blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Microvessel Ultrasound Imaging of Wound Healing in Patients With Chronic Ulcers
Status: RECRUITING
Conditions: Non-Healing Ulcer of Skin|Non-healing Wound|Lower Extremity Wound
Interventions: DIAGNOSTIC_TEST: Microvessel Ultrasound Examination|PROCEDURE: Skin Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Test for Risperdal 2mg of Janssen Korea
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Risperdal OD Tab. 2mg|DRUG: Risperdal Quicklet Tab. 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Monascus Garlic Fermented Extract on Serum Triglyceride Level
Status: COMPLETED
Conditions: Hypertriglyceridemias
Interventions: DIETARY_SUPPLEMENT: Monascus Garlic Fermented Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of ESWT Treatment in Post-stroke Patients With Triceps Sural Spasticity
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: ESWT + Stretching|PROCEDURE: ESWT and SHAM + Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
Status: NOT_YET_RECRUITING
Conditions: Ametropia|Myopia|Hyperopia|Astigmatism
Interventions: DEVICE: Lehfilcon A spherical contact lenses|DEVICE: Lehfilcon A toric contact lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia
Status: RECRUITING
Conditions: Deglutition Disorders
Interventions: DEVICE: Optimized transcranial Direct Current Stimulation|DEVICE: Sham transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dextenza Compared to Topical Fluorometholone in Patients With Ocular Rosacea
Status: WITHDRAWN
Conditions: Ocular Rosacea
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Fluoromethalone .01%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substrate Ablation Guided by High Density Mapping in Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Routine substrate ablation without pulmonary vein Isolation|PROCEDURE: Routine conventional ablation with pulmonary vein Isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability, Pharmacokinetics and Safety Evaluation of Phencynonate Hydrochloride in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Phencynonate hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)
Status: COMPLETED
Conditions: Mucopolysaccharidosis IIIB
Interventions: DRUG: SBC-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Interval Training on Glucose Tolerance in Children and Adolescents With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: OTHER: Educational intervention|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma
Status: COMPLETED
Conditions: Rectal Cancer Stage II|Rectal Cancer Stage III
Interventions: PROCEDURE: total mesorectal excision / long course radiochemotherapy|RADIATION: long course 5-FU bases radiochemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of rhuMAb IFNalpha in Adults With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: rhuMAb IFNalpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Evaluation of the Physiological Effects of Arabinoxylan-oligosaccharides (AXOS) in Healthy Subjects (Juniors)
Status: COMPLETED
Conditions: Gastrointestinal Health|Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Wheat Bran Extract|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mifepristone Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Use Disorders|Alcohol Abuse|Alcoholism
Interventions: DRUG: Mifepristone 1200 mg daily|BEHAVIORAL: Standardized behavioral therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Intercostal Block Versus Epidural Analgesia in Eventration: Prospective Observational Study
Status: RECRUITING
Conditions: Eventration|Regional Anesthesia|Epidural; Anesthesia|Abdominal Hernia
Interventions: PROCEDURE: undergo|DEVICE: ultrasound|DRUG: Local anesthetic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema
Status: RECRUITING
Conditions: Lymphedema, Secondary|Lymphedema of Upper Limb|Lymphedema, Lower Limb|Lymphedema Arm|Lymphedema of Leg
Interventions: PROCEDURE: Lymphaticovenous anastomosis|PROCEDURE: Sham surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurorehabilitation After Traumatic Brain Injury: Functional Magnetic Resonance Imaging Study
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: PROCEDURE: transcranial direct current stimulation|PROCEDURE: Specific cognitive rehabilitation|PROCEDURE: Nonspecific cognitive rehabilitation|PROCEDURE: transcranial direct current stimulation sham|RADIATION: functional Magnetic Resonance Imaging n-back task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FL-101 in Surgically Resectable Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: FL-101|DRUG: Nivolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma During Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Autologous Platelet-Rich Plasma|DEVICE: Angel Concentrated Platelet Rich Plasma System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Istaroxime Infusion for 24 Hours in Chinese Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: istaroxime|DRUG: 9% Saline (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Call From Acute Care Physicians to Long Term Care Physicians: Impact on Transitional Care of Elderly Patients
Status: COMPLETED
Conditions: Alzheimer Disease|Parkinson Disease|Dysphagia
Interventions: PROCEDURE: TELEPHONE CALL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Mobile Preconception Lifestyle Programme in Couples Undergoing In Vitro Fertilisation
Status: TERMINATED
Conditions: Infertility
Interventions: BEHAVIORAL: PreLiFe-programme|BEHAVIORAL: Attention Control Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Prebiotic FOS on Intestinal Abundance of Faecalibacterium Prausnitzii in Patients With Crohn´s Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: FOS|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dexpramipexole and Cimetidine Drug Drug Interaction (DDI)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Dexpramipexole|DRUG: Cimetidine plus Dexpramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of De-stress and Focus Capsule in the Management of Stress.
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Stress|Stuporous
Interventions: OTHER: De-Stress and Focus capsule- U001|OTHER: De-Stress and Focus capsule - I001|OTHER: Placebo capsules 001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infliximab in Treating Cancer-Related Fatigue in Postmenopausal Women Who Have Undergone Treatment for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Fatigue
Interventions: BIOLOGICAL: infliximab|OTHER: Clinical Assessment|OTHER: Self-report questionnaires|OTHER: Immune Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Systemic Antibiotic Therapy on Postoperative Complications in Patients Undergoing Wisdom Teeth Removal Surgery.
Status: COMPLETED
Conditions: Third Molar Extraction Surgery
Interventions: DRUG: Amoxilan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Placebo|DRUG: ABT-494
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Types of Papilla Incision in Periodontal Surgery
Status: RECRUITING
Conditions: Periodontitis|Periodontal Diseases|Periodontal Pocket
Interventions: PROCEDURE: Midline interproximal soft-tissue incision|PROCEDURE: Marginal approach by palatal incision|PROCEDURE: Minimally invasive surgical technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic (PK) Study to Assess Bronchopulmonary Disposition of IV Eravacycline (TP-434) in Healthy Men and Women
Status: COMPLETED
Conditions: Normal Drug Tolerance
Interventions: DRUG: TP-434 (Eravacycline) reconstituted and administered via an IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Reiki on Pain, Anxiety and Haemodynamic Parameters in Patients Receiving Mechanical Ventilator Support
Status: NOT_YET_RECRUITING
Conditions: İntensive Care|Nursing|Reiki
Interventions: BEHAVIORAL: Reiki|OTHER: (Sham Reiki)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of the Effectiveness of Progressive Relaxation Techniques in Individuals With Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Progressive Muscle Relaxation|BEHAVIORAL: Relaxative Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Fazirsiran Injection (TAK-999, ARO-AAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline for Long-term Nicotine Replacement Therapy (NRT) Users
Status: UNKNOWN
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: support and visits|DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: rosiglitazone/glimepiride fix dose combination|DRUG: glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers (LLL&DIAB-03)
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: B-Cure laser pro|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood
Status: TERMINATED
Conditions: Perimenopausal Disorder|Stress, Emotional
Interventions: DRUG: Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release|DRUG: Placebo Patch|DRUG: Progesterone Capsule|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Aflibercept|DRUG: 5-Fluoruracil|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-Study of the PREVIEW Study Australia
Status: UNKNOWN
Conditions: Pre-diabetes|Obesity
Interventions: BEHAVIORAL: Low calorie diet administered from 0 to 2 months|BEHAVIORAL: High Protein / Low Glycaemic Index|BEHAVIORAL: Moderate Protein / High Glycaemic Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting for Lifelong Health (PLH) - Masayang Pamilya (MaPa) Evaluation Study
Status: COMPLETED
Conditions: Child Maltreatment
Interventions: BEHAVIORAL: Masayang Pamilya Para Sa Batang Pilipino Parenting Programme (MaPa)|OTHER: Parenting Effectiveness Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India
Status: RECRUITING
Conditions: Anemia
Interventions: BIOLOGICAL: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and Fill Technique
Status: UNKNOWN
Conditions: Oral Health Related Quality of Life|Early Childhood Caries
Interventions: OTHER: silver diamine fluoride|OTHER: conventional composite resin restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Innovative and Traditional Ventilation Strategies on Atelectasis and Prognosis in Elderly Patients
Status: RECRUITING
Conditions: Ventilator-associated Lung Injury|Atelectasis|Postoperative Pulmonary Complications
Interventions: PROCEDURE: Traditional ventilation strategies|PROCEDURE: Traditional lung-protective ventilation strategies|PROCEDURE: Innovative lung-protective ventilation strategies|PROCEDURE: Lung-protective ventilation|PROCEDURE: negative pressure extubation|PROCEDURE: positive pressure extubation|PROCEDURE: postoperative breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: State-dependent Pathophysiological Oscillations in Parkinson's Disease and Treatment With DBS Using the Medtronic RC+S
Status: WITHDRAWN
Conditions: Parkinson Disease|Parkinson
Interventions: DEVICE: Medtronic RC+S DBS system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|CLL
Interventions: DRUG: Oblimerson sodium, G3139
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teleconsultations Hypnosis Sessions for Patients With Peripheral Chronic Neuropathic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Neuropathy|Pain
Interventions: OTHER: Clinical examination|OTHER: Anxiety and Depression Scale (HAD)|PROCEDURE: pain scale|PROCEDURE: hypnosis consultation|PROCEDURE: Maintenance|OTHER: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short and Long-arm Fiberglass Cast Immobilization for Distal Salter Harris I and II Forearm Fractures in Children
Status: RECRUITING
Conditions: Fracture Forearm
Interventions: DEVICE: short-arm fiberglass cast|DEVICE: long-arm fiberglass cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection (RCT)
Status: UNKNOWN
Conditions: Analgesic Drugs|Pain Relief
Interventions: DRUG: Ibuprofen|DRUG: paracetamol|DIETARY_SUPPLEMENT: A fruit-flavored orange color placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Dental Implants Placed in Posterior Maxillary Ridge Using Densah Burs Versus Standard Drills
Status: UNKNOWN
Conditions: Implant Site Reaction
Interventions: DEVICE: densah burs osseo densification drills|DEVICE: conventional surgical burs drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PRX302 for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: PRX302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cantharidin and Occlusion in Verruca Epithelium
Status: COMPLETED
Conditions: Common Wart|Warts Hand|Warts|Papillomavirus Infections|DNA Virus Infections|Skin Diseases, Viral|Skin Diseases, Infectious|Skin Diseases|Virus Diseases|Tumor Virus Infections|Verruca Vulgaris|Verruca
Interventions: COMBINATION_PRODUCT: VP-102 Cantharidin topical film forming solution|COMBINATION_PRODUCT: VP-102 Cantharidin, topical film forming solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified Graded Motor Imagery Training in Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Graded Motor Imagery|Stroke|Action Observation Training|Motor Imagery
Interventions: OTHER: Modified Graded Motor Imagery and Conventional Treatment Group|OTHER: Graded Motor Imagery and Conventional Treatment Group|OTHER: Conventional Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retention of Whole-body Training Effects on Ambulatory Function in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: CP|Gait Disorders, Neurologic|Locomotion Disorder, Neurologic
Interventions: OTHER: Whole body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)
Status: ACTIVE_NOT_RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: rAAV2tYF-GRK1-RPGR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Truthful Information on Chemotherapy and Its Impact on Chemotherapy at the End of Life
Status: COMPLETED
Conditions: Stage IV Lung Cancer
Interventions: BEHAVIORAL: Truthful information on chemotherapy risks|BEHAVIORAL: Standard of information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fatigue in Breast Cancer Patients Undergoing Radiotherapy-eSMART-MH
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: BEHAVIORAL: eSMART-MH|OTHER: Mobile Mood Tracking (Mood 24/7)|BEHAVIORAL: Theater Testing Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Safety and Efficacy of Ophtesis Bio 3% With a Similar 3% Sodium Hyaluronate OVD
Status: RECRUITING
Conditions: Bilateral Cataract|Unilateral Cataract
Interventions: DEVICE: Ophtesis Bio 3% ophthalmic viscosurgical device|DEVICE: Healon Endocoat 3% ophthalmic viscosurgical device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic and Injection Site Toleration of BIOD-238 and BIOD-250 Compared to Humalog® in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin LISPRO|DRUG: Insulin LISPRO|DRUG: Insulin LISPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment and Recovery Monitoring of Post TBI Symptoms
Status: COMPLETED
Conditions: Brain Injuries, Traumatic
Interventions: DEVICE: Active repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leucovorin, Fluorouracil, Cetuximab, and Oxaliplatin in Treating Patients With Stage IV Colorectal Cancer and Liver Metastases That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satiety and Glucose Indices in Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: 300 mg SC|DIETARY_SUPPLEMENT: 500 mg SC|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Ability of Virtual Reality Glasses in Anxiety and Pain Reduction in 50 Women Undergoing Amniocentesis or Feticide
Status: UNKNOWN
Conditions: Anxiety Acute|Amniocentesis|Foeticide
Interventions: DEVICE: virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiation Therapy Plus Cisplatin and Gemcitabine in Treating Patients With Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Small Cell Carcinoma|Cervical Squamous Cell Carcinoma|Stage IB Cervical Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage IVA Cervical Cancer
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Cisplatin|RADIATION: Radiation Therapy|RADIATION: Internal Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluaing the Efficacy, Safety, and Patient Satisfaction of Injectable Hylaronic Acid With 0.3% Lidocain Hydrochloride, Prevelle Silk, for Superficial, Vertical Perioral Lines and Superficial, Horizontal, Lateral Canthal Lines
Status: UNKNOWN
Conditions: Wrinkles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Early Extracorporeal Diaphragm Pacing Combined With Tilt Table in Ventilated Patients.
Status: NOT_YET_RECRUITING
Conditions: Early Mobilization|Critically Ill|Mechanical Ventilation|Diaphragm Dysfunction
Interventions: DEVICE: Extracorporeal Diaphragm Pacing|DEVICE: Tilt Table Verticalization|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role Of Wound Lavage in Direct Pulp Capping Of Permanent Teeth With Carious Exposure
Status: ACTIVE_NOT_RECRUITING
Conditions: Reversible Pulpitis
Interventions: PROCEDURE: wound lavage with normal saline|PROCEDURE: wound lavage with sodium hypochlorite|PROCEDURE: wound lavage with Ethylenediaminetetraacetic acid(EDTA)|PROCEDURE: wound lavage with sodium hypochlorite followed by Ethylenediaminetetraacetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3451838 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3451838|DRUG: Placebo|DRUG: Placebo|DRUG: LY3451838
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vorolanib Plus Sintilimab for Advanced Renal Cell Carcinoma After Failure of Prior Immune Checkpoint Inhibitors Based Combination Therapy
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma|Immunotherapy|Molecular Targeted Therapy
Interventions: DRUG: Vorolanib Tablets|DRUG: Sintilimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT