pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: TEAS Reduces Remifentanil Consumption
Status: COMPLETED
Conditions: Anesthesia|Pain
Interventions: DEVICE: acupoint stimulation|DEVICE: single acupoint|DEVICE: dual acupoints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Matrix Metalloproteinases Neutralizing Agents in Oral Lichen Planus
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Matrix Metalloproteinase Inhibitors (Orochem)|DRUG: Kenacort A,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of an Amoxicillin and Amoxicillin/Clavulanic Acid Resistant Probiotic on Key Clinical Outcomes in Children Treated With Amoxicillin or Amoxicillin/Clavulanic Acid
Status: RECRUITING
Conditions: Bacterial Infections
Interventions: DRUG: Antibiotic Treatment|DIETARY_SUPPLEMENT: Probiotic Bifidobacterium breve PRL2020 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy and Tazemetostat for Locally Advanced SMARCB1-deficient Sinonasal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Sinonasal Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Cis Platinum|DRUG: 5-FU|DRUG: Tazemetostat|PROCEDURE: Surgery|OTHER: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Quercetin to Treat Fibrotic Non-alcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: NAFLD|NASH With Fibrosis|Liver Fibrosis
Interventions: DRUG: Dasatinib 100 MG + Quercetin (1000 MG)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Changes of GCF Levels of RANKL and Osteoprotegerin in Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: periodontal phase 1 therapy|PROCEDURE: gingival crevicular fluid collection|OTHER: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Health and Energy Through Active Living Every Day After Cancer Intervention for Cancer Survivors
Status: COMPLETED
Conditions: Quality of Life|Cognitive Decline|Fatigue|Sleep|Anxiety|Depression
Interventions: BEHAVIORAL: Physical activity experiment|BEHAVIORAL: Balance and flexibility control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Supplementation in IBS
Status: TERMINATED
Conditions: Irritable Bowel Syndrome|Vitamin D Deficiency|Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Drug-Drug Interaction Between THC and AEF0117
Status: NOT_YET_RECRUITING
Conditions: Cannabis Abuse
Interventions: DRUG: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Safety Study Of DIC075V (Intravenous Diclofenac Sodium) In Patients With Acute Post-Operative Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: DIC075V (intravenous diclofenac sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Bioavailability and Pharmacokinetic Study of TNX-102 2.4 mg and Cyclobenzaprine 5 mg Tablets in Healthy Adults.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti Free Radical & Anti Inflammatory Effect & Safety of Rebamipide in Chronic Gastritis
Status: COMPLETED
Conditions: Dyspepsia|Chronic Gastritis
Interventions: DRUG: Rebamipide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Mechanisms of Autism : an MRI and Social Cognition Study
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: MRI|DEVICE: Eye-tracking|OTHER: Clinical Scales|GENETIC: Research of genetic anomalies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ofatumumab in Patients With Relapsed/Progressive Diffused Large B-Cell Lymphoma (DLBCL) Ineligible for or Relapse/Progression After Transplant
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Diffuse
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hidradenitis Suppurativa Patient Experience With Humira Treatment
Status: WITHDRAWN
Conditions: Hidradenitis Suppurativa
Interventions: OTHER: Electronic Reporting|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Ethanol Extracts of Porphyra Tenera(PTE10) on Promotion of Immunity
Status: UNKNOWN
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: Ethanol Extracts of Porphyra Tenera(PTE10)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Strategies to Promote Muscle Protein Anabolism in the Elderly
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Protein/Amino Acids|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Multifocal Toric Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: etafilcon A Investigational Toric Multifocal Contact Lens|DEVICE: etafilcon A Investigational Toric Multifocal Contact Lens|DEVICE: etafilcon A Investigational Toric Multifocal Contact Lens|DEVICE: etafilcon A Investigational Toric Multifocal Contact Lens|DEVICE: etafilcon A Investigational Toric Multifocal Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of MEDI8897 for the Prevention of Medically Attended Respiratory Syncytial Virus(RSV) Lower Respiratory Track Infection (LRTI) in High-risk Children
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: MEDI8897|DRUG: Palivizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Delivery of Levodopa in Patients With Advanced Idiopathic Parkinsons Disease - Cost-benefit
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Levodopa (drug), intraduodenal administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remote Ischemic Preconditioning in Patients Undergoing Major Liver Surgery
Status: UNKNOWN
Conditions: Ischemia Reperfusion Injury
Interventions: OTHER: remote preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Risk of Hyperbilirubinemia in Term Newborns After Placental Transfusion
Status: COMPLETED
Conditions: Jaundice Neonatal
Interventions: OTHER: Delayed cord clamping|OTHER: Cord milking|OTHER: Early cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of EDP-514 in Patients With Chronic Hepatitis B Virus Infection Who Are Not Currently on Treatment
Status: COMPLETED
Conditions: Chronic HBV Infection
Interventions: DRUG: EDP-514|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Compared to Magnetic Navigation in Ablation for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Magnetic navigation|PROCEDURE: Ablation performed with manual navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytoreductive Surgery (CRS) With/Without HIPEC in Gastric Cancer With Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Malignant Neoplasm of Stomach|Secondary Malignant Neoplasm of Peritoneum|Secondary Malignant Neoplasm of Other and Unspecified Sites
Interventions: PROCEDURE: HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Antibacterial Effect of 810 nm Diode Laser and Photodynamic Therapy
Status: UNKNOWN
Conditions: Periradicular Disease
Interventions: DEVICE: diode laser|DEVICE: diode laser|DRUG: Methylene blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Mirtazapine|DRUG: Sumatriptan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Ultrasound Doses on Median Nerve Conduction Parameters
Status: RECRUITING
Conditions: Entrapment Neuropathies
Interventions: DEVICE: Pulsed Ultrasound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The iTAP Study for Veterans
Status: COMPLETED
Conditions: Insomnia|Alcohol; Harmful Use
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Hygeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabergoline for the Treatment of Chronic Pain Due to Endometriosis
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Cabergoline 0.5 MG|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lorlatinib After Failure of First-line TKI in Patients With Advanced ROS1-positive NSCLC (ALBATROS)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolism (VTE)
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Children Under 2 Years
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Standard of care (SOC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: fluoride varnish 22600ppm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans
Status: RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: MitoQ|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Blood Transplant for Children With Lymphoid Hematological Malignancies
Status: WITHDRAWN
Conditions: Lymphoid Hematological Malignancies|Umbilical Cord Blood Transplant
Interventions: DRUG: Cytoxan|DRUG: Fludarabine|RADIATION: Total Body Irradiation (TBI)|PROCEDURE: Cord Blood Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction
Status: RECRUITING
Conditions: Sacroiliac Joint Dysfunction|Sacroiliac; Fusion|Sacroiliac Disorder|Sacroiliac Joint Pain
Interventions: DEVICE: Use of iFuse TORQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis
Status: RECRUITING
Conditions: Cardiac Amyloidosis|AL Amyloidosis|ATTR Amyloidosis
Interventions: DRUG: [18F]florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward
Status: NOT_YET_RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Amoxicillin|DRUG: Amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meaning-Centered Counseling for Chinese Patients Who Are Being Treated for Advanced Cancer
Status: RECRUITING
Conditions: Advanced Cancer
Interventions: BEHAVIORAL: In-depth Patient Interviews|BEHAVIORAL: Adaptation of IMCP for Chinese Immigrant Cancer Patients|BEHAVIORAL: Individual Meaning-Centered Psychotherapy for Chinese (IMCP-Ch) (For Phase 3 and Phase 4)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma.
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DEVICE: Patient-led surveillance|BEHAVIORAL: Clinician-led surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of the Combination Bismuth + Neomycin + Procaine in the Treatment of Recurrent Aphthous Ulceration
Status: COMPLETED
Conditions: Aphtous Ulcers
Interventions: DRUG: Bismu-Jet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BYL719 in Combination With Gemcitabine and (Nab)-Paclitaxel in Locally Advanced and Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: BYL719|DRUG: Gemcitabine|DRUG: (nab)-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individuals With Lumbar Disc Hernia Exercising With Virtual Reality Glasses
Status: COMPLETED
Conditions: To Evaluate the Effect of Exercise With Virtual Glasses on Pain, Activities of Daily Living and Quality of Life
Interventions: OTHER: Exercising with virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer (TORCH-E）
Status: RECRUITING
Conditions: Early Low Rectal Cancer
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: Short-course radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotic Fructans to Reduce Number of Febrile Infections in Children
Status: COMPLETED
Conditions: Infectious Disease|Children, Only|Diet Modification
Interventions: DIETARY_SUPPLEMENT: prebiotic inulin-type fructans|DIETARY_SUPPLEMENT: placebo maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decreasing Youth Involvement in Violence in Burundi
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Aggression
Interventions: BEHAVIORAL: Narrative Exposure Therapy for Forensic Offender Rehab|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 and mDCF Followed by Chemoradiotherapy in Patients With Stage III Squamous Cell Anal Carcinoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Anus Stage III
Interventions: BIOLOGICAL: Blood sample collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Text Reminders Improve Uptake of Cervical Screening?
Status: COMPLETED
Conditions: Cervical Carcinoma|Cervical Dysplasia
Interventions: OTHER: Neutral text message reminder|OTHER: Messenger text message reminder|OTHER: Social Norms A reminder|OTHER: Social Norms B reminder|OTHER: Framed Gain text reminder|OTHER: Framed Loss text reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Trial of Mannitol Cream for Pain Relief After a Long Run
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Mannitol cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Memantine add-on in the Treatment of Bipolar Disorder (Type I) Nonresponders or Partial Responders Patients
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV
Status: ENROLLING_BY_INVITATION
Conditions: Resilience|HIV-1-infection|Stress, Psychological
Interventions: BEHAVIORAL: RISE+|BEHAVIORAL: Stress Reduction Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease
Status: RECRUITING
Conditions: Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control
Interventions: OTHER: PPI and T50 dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
Status: COMPLETED
Conditions: Sleep Disorder, Shift-Work
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ischemic Pain Control With Analgesic Methods Clinical Trial
Status: UNKNOWN
Conditions: Arterial Occlusive Diseases
Interventions: PROCEDURE: Continuous peripheral sciatic nerve block|DRUG: Fentanyl|DRUG: Ropivacaine|DEVICE: Perineural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Electrocardiographic Effects of Ponesimod in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ponesimod Placebo|DRUG: Moxifloxacin Placebo|DRUG: Ponesimod 10 mg|DRUG: Ponesimod 20 mg|DRUG: Ponesimod 40 mg|DRUG: Ponesimod 60 mg|DRUG: Ponesimod 80 mg|DRUG: Ponesimod 100 mg|DRUG: Moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Physiological Regulation of Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: OTHER: fMRI Neurofeedback|OTHER: EEG Neurofeedback|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: sitagliptin|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia in Remission|de Novo Myelodysplastic Syndrome|Fanconi Anemia|Previously Treated Myelodysplastic Syndrome
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ventilation Mode on Lung Deposition of a Radiolabeled Aerosol During Mechanical Ventilation: Barometric Versus Volumetric
Status: COMPLETED
Conditions: Post-operative Neurosurgery
Interventions: DRUG: technetium-99m - Diethylenetriaminepentaacetic acid|DEVICE: Vibrating-mesh nebulizer|OTHER: Gamma scintigraphy|OTHER: Preoperative spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure and Central Vascular Stiffness in Obese Children. Relationship to Metabolic Disturbances and Subclinical Cardiovascular Damage. Effect of Weight Reduction
Status: UNKNOWN
Conditions: Central Blood Pressure|Obesity|Subclinical Organ Damage|Children|Adolescent
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Ketone Supplementation and Cardiometabolic Health
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Ketone drink|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intraperitoneal Docetaxel in Combination With mFOLFOX6 for Gastric Cancer Patients With Peritoneal Carcinomatosis
Status: TERMINATED
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Intraperitoneal docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Arthroplasty Complications
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Ultrasound-Guided Axillary Brachial Plexus Block: Influence of Obesity on Block Performance Time, Failure Rate and Incidence of Acute Complications (Observational Study)
Status: COMPLETED
Conditions: Obesity, Ultrasound Guided Axillary Brachial Plexus Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vestibular Stimulation to Treat Hemispatial Neglect
Status: COMPLETED
Conditions: Hemispatial Neglect|Stroke
Interventions: DEVICE: Transcutaneous current to the vestibular nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of a Perceptual Learning Module on Spinal Ultrasound Among Residents.
Status: RECRUITING
Conditions: Spinal Anesthesia Skill|Ultrasound Imaging of Anatomical Structures|Medical Education
Interventions: OTHER: Perceptual learning module|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Glutamine in Management of Radiation Mucositis
Status: RECRUITING
Conditions: Radiation-Induced Mucositis
Interventions: DIETARY_SUPPLEMENT: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Are Patients Willing and Capable of Removing Their Own Non-absorbable Sutures
Status: COMPLETED
Conditions: Suture Removal
Interventions: PROCEDURE: Suture self removal|PROCEDURE: Suture removal by family doctor or clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Combination With TACE/TAE for Patients With Intermediate Stage HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Nivolumab and TACE/TAE|PROCEDURE: TACE/TAE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Depth of Small Bowel Insertion at Push Enteroscopy by Using Capsule Endoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Obscure Gastrointestinal Bleeding|Gastrointestinal Diseases|Gastrointestinal Bleed|Angiodysplasia Intestine
Interventions: DIAGNOSTIC_TEST: Push enteroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of SJP-0035 Ophthalmic Solution in Patients With Moderate to Severe Corneal Epithelial Disorders
Status: COMPLETED
Conditions: Corneal Epithelial Disorders
Interventions: DRUG: SJP-0035 Ophthalmic Solution|DRUG: Vehicle of SJP-0035 Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I BP Interferon (IFN) Beta-004
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Interferon beta-1a HSA-free biosimilar|DRUG: Interferon beta-1a HSA+ biosimilar|DRUG: Interferon beta-1a original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MVC-COV1901 Vaccine Against COVID-19 in Adolescents
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901(S protein with adjuvant)|BIOLOGICAL: MVC-COV1901(Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia
Status: WITHDRAWN
Conditions: Community Acquired Bacterial Pneumonia|Complicated Intra-Abdominal Infection
Interventions: DRUG: Tigecycline|DRUG: Tigecycline|DRUG: cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside|DRUG: CAP: Ceftriaxone, plus if applicable oral clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6244 Versus Pemetrexed (Alimta®) in Patients With Non-small Cell Lung Cancer, Who Have Failed One or Two Prior Chemotherapy Regimen
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: AZD6244|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Multi-Ingredient Pre-Workout Supplement on Body Composition, Performance, Muscular Properties, and Wellbeing in Adults.
Status: NOT_YET_RECRUITING
Conditions: Protein Deficiency|Training Group, Sensitivity|Fatigue|Muscular Atrophy|Psychological
Interventions: DIETARY_SUPPLEMENT: Ingestion of a Pre-Workout Supplement|DIETARY_SUPPLEMENT: Ingestion of a Maltodextrin Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Aromatase at the Navelbine in Pretreated Metastatic Breast Cancer.
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Letrozole|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Periorbital Hyperpigmentation
Status: COMPLETED
Conditions: Periorbital Hypermelanosis
Interventions: DEVICE: carboxy therapy|DEVICE: Dermapen with topical glutathione
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of GFH018 and Toripalimab in Combination With Concurrent Chemoradiotherapy in Stage III NSCLC Chemoradiotherapy in Stage III NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC, Stage III
Interventions: DRUG: GFH018|DRUG: Toripalimab|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|RADIATION: Thoracic Radiation Therapy (TRT)|DRUG: GFH018
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Pharmacokinetics and Pharmacodynamics of 6 mg RGB-02 to 6 mg Neulasta
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: RGB-02 or Neulasta® (pegfilgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomas
Status: UNKNOWN
Conditions: Anaplastic Oligoastrocytoma|Anaplastic Astrocytoma|Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: α-IFN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Rapastinel|DRUG: Placebo-matching Rapastinel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Use of Dermal Matrix to Compensate Dimensional Changes in the Reconstructive Therapy of Peri-implantitis
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: OTHER: Dermal matrix (Oracell, LifeNet, USA)|OTHER: No dermal matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Treatment With Aprepitant (Emend®) in HIV Infected Individuals. 375 mg Dose
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Aprepitant|DRUG: Aprepitant placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat With XRT and 5-FU for Locally Advanced Adenocarcinoma of the Pancreas
Status: TERMINATED
Conditions: Pancreatic Cancer|Adenocarcinoma of the Pancreas
Interventions: RADIATION: Radiation therapy|DRUG: 5-FU|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DRUG: intraarticular administration of tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anti-inflammatory Cryoagent on the Level of Postoperative Pain in Patients with Symptomatic Irreversible Pulpitis and Apical Periodontitis.
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of an Enriched Surimi in Abdominal Visceral Adiposity
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: COMBINATION_PRODUCT: Surimi intervention|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EFFECT OF CHEWING GUM ON CONTROLLING NAUSEA/VOMITING AND THIRST IN PATIENTS WITH ACUTE PANCREATITIS
Status: RECRUITING
Conditions: Acute Pancreatitis|Thirst
Interventions: OTHER: Gum group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Borage and Echium Seed Oils for Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Borage and Echium Seed Oils|DIETARY_SUPPLEMENT: Corn oil pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults
Status: COMPLETED
Conditions: Vascular Aging
Interventions: DRUG: Placebo|DRUG: High-dose trehalose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dasatinib and Rituximab for Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Dasatinib and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Immunoglobulin Treatment for Multifocal Motor Neuropathy
Status: COMPLETED
Conditions: Multifocal Motor Neuropathy
Interventions: DRUG: Subcutaneous immunoglobulin|DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ketamine Versus Placebo for Treating Depression in Patients Undergoing Treatment for Cancer
Status: COMPLETED
Conditions: Cancer|Depression
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Her2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastasis
Interventions: DRUG: Neratinib maleate in combination with capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Technology-Enabled AFib Management
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Behavior
Interventions: COMBINATION_PRODUCT: Corrie Virtual Atrial Fibrillation Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Parasternal Block for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Disease|Analgesia|Acute Pain|Postoperative Pain
Interventions: PROCEDURE: Parasternal Block+ Infiltration with local anesthetic of access to thoracic drainage|PROCEDURE: Infiltration with local anesthetic of access to thoracic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resminostat (YHI-1001) in Combination With Sorafenib in Asian Patients With Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Resminostat|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Autologous Tumor Cell-TLR9 Agonist Vaccination for Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Neoplasms|Anal, Colon, and Rectal Cancers
Interventions: BIOLOGICAL: Autologous tumor cell + CpG vaccine|PROCEDURE: Autologous hematopoietic and immune cell rescue (transplantation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAmpto-CISplatine Plus Radiotherapy in Advanced Cervix Cancer : Search of Tolerated Maximum Dose of Campto
Status: COMPLETED
Conditions: Cervix Cancer
Interventions: DRUG: campto (irinotecan)|DRUG: cisplatin (cisplatyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Obstetric Cook Double Balloon Catheter in Combination With Oral Misoprostol for Induction of Labor
Status: UNKNOWN
Conditions: Labor Induction
Interventions: DRUG: Misoprostol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Primary Progressive Multiple Sclerosis
Interventions: DRUG: Rituximab|DRUG: Ocrelizumab|DRUG: Fexofenadine|DRUG: Paracetamol|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 and Bryostatin 1 in Treating Patients With Advanced Kidney Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: BIOLOGICAL: aldesleukin|DRUG: bryostatin 1|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dapagliflozin on Vascular Functions in Patients With Type 2 Diabetes Compared to Gliclazide
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study Evaluating the Feasibility of Fiducial Markers Placement for Patients With Esophageal or Rectal Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasm|Rectal Neoplasms
Interventions: DEVICE: fiducial markers placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mobile Technology Monitoring System to Assess a Web-based Intervention for Teen Risky Driving
Status: COMPLETED
Conditions: Adolescent|Accidents, Traffic|Attention|Motor Vehicles
Interventions: BEHAVIORAL: Risky Driving Prevention|BEHAVIORAL: Teen Healthy Living
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photo-therapy With a Topical Retinoid Versus Photo-therapy Alone for Actinic Keratoses
Status: WITHDRAWN
Conditions: Actinic Keratoses
Interventions: PROCEDURE: Topical retinoid and blue-light therapy with photosensitizing agent|PROCEDURE: Photodynamic Therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Hydroxychloroquine With FOLFIRI and Bevacizumab in DTP-high Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Hydroxychloroquine|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dexketoprofen on Shoulder Pain Using Different Physiotherapy Treatments
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Ultrasound|PROCEDURE: Phonophoresis|PROCEDURE: Iontophoresis|PROCEDURE: Exercises|PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tagraxofusp to Eradicate Measurable Residual Disease in Patients With Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|BIOLOGICAL: Tagraxofusp-erzs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)
Status: UNKNOWN
Conditions: Aorta Aneurysm|Aorta Dissection|Aorta Stenosis|Aortic Coarctation|Aortic Rupture|Aortic Valve Disease|Aortic Valve Stenosis
Interventions: DEVICE: Perclose Proglide (Abbott)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Online Education Given to Young Adults on Testicular Cancer Health Beliefs and Behaviors
Status: COMPLETED
Conditions: Testicular Neoplasms
Interventions: DIAGNOSTIC_TEST: Testicular Model BSE/TSE Training Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: POSE2.0 With GLP-1 Agonist for Obesity Management
Status: RECRUITING
Conditions: Obesity
Interventions: DEVICE: POSE2.0 Endoscopic Gastric Remodeling|DRUG: Liraglutide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: Warfarin|DRUG: Daridorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin on top of intensive insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Carboxymethylcellulose Based Eye Drop Formulation A|DRUG: Carboxymethylcellulose Based Eye Drop Formulation B|DRUG: Carboxymethylcellulose Based Preservative-Free Lubricant Eye Drops|DRUG: Carboxymethylcellulose Based Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulatory Lymphocytes in Patients Treated With Specific Immunotherapy
Status: COMPLETED
Conditions: Immunotherapy|Seasonal Allergic Rhinitis
Interventions: DRUG: Allergovit|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE