pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Safety Study Of BMP-655/ACS As An Adjuvant Therapy For Treatment Of Rotator Cuff Tears
Status: TERMINATED
Conditions: Rotator Cuff Tear
Interventions: BIOLOGICAL: BMP-655/ACS+Standard of care or Standard of care|BIOLOGICAL: BMP-655/ACS+Standard of care or Standard of care|BIOLOGICAL: BMP-655/ACS+Standard of care or Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liraglutide for HIV-associated Neurocognitive Disorder
Status: TERMINATED
Conditions: HIV Infection|Diabetes Mellitus Type 2|Obesity|Overweight|Metabolic Syndrome
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Cognitive Rehabilitation of Executive Dysfunction in Nonamnestic MCI
Status: UNKNOWN
Conditions: Nonamnestic Mild Cognitive Impairment|Cognitive Dysfunction|Cognitive Disorder|Neurocognitive Disorders|Mental Disorder|Cognitive Impairment, Mild
Interventions: BEHAVIORAL: Online Goal Management Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Lumbar Spinal Stenosis
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis
Interventions: DEVICE: Acunpuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Drugs on Headache Treatment After ECT Treatment
Status: UNKNOWN
Conditions: Mental Disorders
Interventions: DRUG: Paracetamol|DRUG: Deksketoprofen trometamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Lumbar Region Temperature During Auricular Acupressure at Kidney Point
Status: COMPLETED
Conditions: Temperature Change, Body
Interventions: PROCEDURE: Auricular acupressure on the left ear|PROCEDURE: Auricular acupressure on the right ear|PROCEDURE: Sham auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LDLA202|DRUG: ONO LDL50|DRUG: Esmolol hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phage Therapy for the Prevention and Treatment of Pressure Ulcers.
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: COMBINATION_PRODUCT: Bacteriophage-loaded Microcapsule Spray|COMBINATION_PRODUCT: Placebo|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Combination of Sintilimab, Ramucirumab and Chemotherapy for First-line Treatment of Gastric Cancer With Liver Metastasis
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms
Interventions: DRUG: Sintilimab|DRUG: Ramucirumab|DRUG: SOX/XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HRS9531 Injections in Overweight or Obese Subjects
Status: NOT_YET_RECRUITING
Conditions: Overweight or Obesity
Interventions: DRUG: HRS9531 injection|DRUG: HRS9531 injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma
Status: TERMINATED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Placebo|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Entire Papilla Preservation technique|PROCEDURE: Modified Minimally invasive Surgical Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intraoperative Deep Neuromuscular Blockade on NOL-guided Opioid Requirement in LSC Colorectal Surgeries
Status: UNKNOWN
Conditions: Laparoscopic Colorectal Surgeries
Interventions: DRUG: Rocuronium IV bolus 0.1 mg/kg guided by TOF that must remain between 1-3 during surgery|DRUG: Rocuronium IV bolus 0.1 mg/kg guided by TOF 0/4 and PTC≤ 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.
Status: COMPLETED
Conditions: Breech Presentation|Pregnancy
Interventions: DRUG: remifentanil|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Copper To Reduce Acquisition Of Microbes and Healthcare-acquired Infections
Status: COMPLETED
Conditions: Healthcare-acquired Infection
Interventions: OTHER: Copper-alloy surfaced patient care objects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nutritional Supplementation in Sarcopenic Obesity
Status: COMPLETED
Conditions: Sarcopenic Obesity
Interventions: DIETARY_SUPPLEMENT: Diet + protein|DIETARY_SUPPLEMENT: Diet + EAA|DIETARY_SUPPLEMENT: Diet + EAA and TCA|OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-3475 in Combination With Docetaxel vs Docetaxel Alone in Non-Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: MK-3475|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial on Efficacy and Safety of Full Dose Tenecteplase Combined With Unfractionated Heparin (UFH) or Enoxaparin in Acute Myocardial Infarction (AMI) in the Prehospital Setting
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Full dose tenecteplase|DRUG: Unfractioned heparin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
Status: UNKNOWN
Conditions: Low Back Pain, Recurrent|Neuropathic Pain|Facet Joint Pain|Central Sensitisation|Aberrant Neuronal Branching|Nociceptive Pain|Mechanical Low Back Pain
Interventions: DEVICE: Radiofrequency COSMAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food-effect Bioavailability of Gemigliptin and Dapagliflozin 50/10 mg
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: gemigliptin and dapagliflozin 50/10 mg film-coated tablet (Fasting)|DRUG: gemigliptin and dapagliflozin 50/10 mg film-coated tablet (fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Image Verified Early Response to Certolizumab Pegol in Subjects With Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Placebo|BIOLOGICAL: Certolizumab Pegol (CZP) 200 mg|BIOLOGICAL: Certolizumab Pegol (CZP) 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surveillance AFter Extremity Tumor surgerY
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Lung Metastases
Interventions: OTHER: Frequency: Every 3 Months|OTHER: Frequency: Every 6 Months|OTHER: Imaging Modality: Chest Radiograph (CXR)|OTHER: Imaging Modality: Chest CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy Anemia
Status: UNKNOWN
Conditions: Thalassemia|Pregnancy
Interventions: DRUG: Colla corii asini
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subclinical Lymphedema Treatment Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer-related Subclinical Lymphedema
Interventions: OTHER: 20-30 mmHg compression sleeve and gauntlet|OTHER: Manual Lymphatic Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise and Nutrition for Healthy AgeiNg
Status: RECRUITING
Conditions: Sarcopenia
Interventions: BEHAVIORAL: Home-based training program|DIETARY_SUPPLEMENT: High-quality protein supplement|DIETARY_SUPPLEMENT: Omega-3 fatty acid|DRUG: Placebo protein powder|DRUG: Placebo omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Sumatriptan|DRUG: Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Remicade in the Treatment of Active Rheumatoid Arthritis Despite Methotrexate (Study P03027)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: Infliximab (Remicade)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation and Comparison of Bilateral Synergy Implants and Bilateral PanOptix Implants
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: AcrySof® IQ PanOptix®|DEVICE: Synergy®|PROCEDURE: Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for DCI
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DRUG: Low dose sildenafil citrate|DRUG: High dose sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate
Status: RECRUITING
Conditions: Rheumatoid Arthritis|JAK Inhibitor|Musculoskeletal Ultrasound|Biomarker
Interventions: DRUG: upadacitinib 15mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Levodopa/Carbidopa/Entacapone vs Levodopa/Carbidopa in Parkinson's Disease Patients With Early Wearing-off
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Levodopa/carbidopa/entacapone|DRUG: Levodopa/carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy
Status: RECRUITING
Conditions: Cancer Of Prostate
Interventions: DRUG: M9241|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Head and Neck Superficial Squamous Cell Carcinoma in Patients With Esophagus Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Optical Enhancement Endoscopy
Interventions: DEVICE: first OE|DEVICE: first WLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel, Carboplatin and Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydration Based on Thoitaine, Aloe Vera and Calendula, in the Prevention of Hand-Foot Syndrome in Patients Using Capecitabine
Status: UNKNOWN
Conditions: Hand-foot Syndrome
Interventions: DRUG: Extremecare|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adaptive Phase I HCV Study With Nucleoside Analogue, in Combination With Interferon and Ribavirin
Status: COMPLETED
Conditions: Healthy Volunteers|Hepatitis C Virus
Interventions: DRUG: RO5024048
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics on Urethral Catheter Withdrawal
Status: COMPLETED
Conditions: Urinary Tract Infection|Bacteriuria
Interventions: DRUG: trimethoprim-sulfamethoxazole|DRUG: ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Telematic Instruction to Patients in the Correct Performance of Respiratory Polygraphy at Home
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Adult
Interventions: OTHER: Video-assisted training|OTHER: Nurse training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification and Assessment of Risk Factors for the Development of Osteoporosis in Adults and Children Living in the Abay Region of the Republic of Kazakhstan Using the Method of Dual-energy X-ray Absorptiometry and Clinical and Epidemiological Research
Status: RECRUITING
Conditions: Improving the Early Diagnosis of Osteoporosis in Adults and Children Living in the Abay Region of Kazakhstan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DRUG: Mouthrinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Carbocysteine Treatment in Obstructive Sleep Apnoea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea
Interventions: DRUG: Carbocysteine|DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab (RTX) Therapy in Patients With Active TAO
Status: ACTIVE_NOT_RECRUITING
Conditions: Ophthalmopathy, Thyroid-Associated
Interventions: DRUG: Rituximab|DRUG: Iv Methylprednisolone|DRUG: peroral methylprednisolone and Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly
Status: COMPLETED
Conditions: Neurocognitive Disorders|Inhalation; Vapor
Interventions: OTHER: General anesthesia with low fresh gas flow|OTHER: General anesthesia with high fresh gas flow|DIAGNOSTIC_TEST: Mini mental state examination|DIAGNOSTIC_TEST: Visual Analogue Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Status: TERMINATED
Conditions: Epidural|Labor Pain|Induction of Labor Affected Fetus / Newborn|Obstetric Anesthesia Problems|Obstetric Pain|Opioid
Interventions: DRUG: Epidural Fentanyl Bolus|DRUG: Standard Epidural Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of IntensiVE Dialysis
Status: COMPLETED
Conditions: Renal Replacement Therapy|Renal Dialysis|End Stage Kidney Disease|End Stage Renal Disease|Uremia
Interventions: PROCEDURE: haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smartphone App to Improve Physical Activity in Older Adults With MCI/Mild Dementia
Status: COMPLETED
Conditions: Sedentary Lifestyle|Dementia, Mild|Mild Cognitive Impairment|Memory and Thinking Problems
Interventions: BEHAVIORAL: Moving Up - A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: NLR and PLR Levels Following iPACK Block in Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Knee Arthropathy|Knee Osteoarthritis|Knee Pain Chronic
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: Ropivacaine 0.2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacology of SGN-40 Administered in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib|DRUG: SGN-40
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Herbal Sleep Formula on Patients With Insomnia and Tinnitus
Status: RECRUITING
Conditions: Sleep Disturbances|Tinnitus
Interventions: DIETARY_SUPPLEMENT: The gel contains a mixture of glucose and maltodextrin|DIETARY_SUPPLEMENT: Herbal compound low-dose|DIETARY_SUPPLEMENT: Herbal compound high-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study of Safety & Immunogenicity of AERAS-456 in HIV-Neg. Adults Treated for Drug-susceptible Pulmonary TB
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: H56:IC31|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Infectious Pathogens in Acute Respiratory Illness in Adults and Elderly
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: PROCEDURE: Blood sample|PROCEDURE: Sputum sample|PROCEDURE: Nasopharyngeal swab|PROCEDURE: Urine sample|PROCEDURE: End tidal breath sample|OTHER: Data collection|OTHER: Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: South Asian HeArt Risk Assessment Project - Trial (SAHARA-Trial)
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Diabetes|Abdominal Obesity
Interventions: BEHAVIORAL: Multimedia Lifestyle Improvement|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Cisplatin/Vinorelbine +/- Cetuximab as First-line Treatment of Advanced Non Small Cell Lung Cancer (FLEX)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: cetuximab + cisplatin + vinorelbine|DRUG: cisplatin + vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massage for Post Breast Surgery
Status: COMPLETED
Conditions: Postmastectomy Lymphedema Syndrome|Pain|Shoulder Mobility Impairment|Breast Surgery
Interventions: OTHER: Myofascial Massage Therapy|OTHER: Global Relaxation Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of QMF149 Twisthaler® in Adolescent and Adult Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QMF149 Twisthaler®|DRUG: Mometasone Twisthaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pilates Exercise Program in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Pilates exercise group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets
Status: WITHDRAWN
Conditions: Brain Metastases|Documented Her2 Overexpression|Advanced Solid Tumor|Neurologically Stable
Interventions: DRUG: MM-302|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapy With Aminoacid Based Formula Versus Hydrolyzed Whey Proteins in Children With Cow's Milk Allergy
Status: COMPLETED
Conditions: Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Aminoacid based formula|DIETARY_SUPPLEMENT: Hydrolyzed whey formula
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Anti-aging Efficacy of Two Dietary Supplements
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Berry extract 1|DIETARY_SUPPLEMENT: Berry extract 2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Sentinel Lymph Node Mapping in Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: PROCEDURE: Gastrectomy|DRUG: Indocyanine Green|OTHER: Iron Conjugated Polymers in Saline Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short vs Long of Usual Treatment for Non Complicated Enterococcal Bacteremia
Status: RECRUITING
Conditions: Enterococcal Bacteremia
Interventions: DRUG: Short-treatment of any active antibiotic regimen 7 days of any active antibiotic treatment for uncomplicated enterococcal bacteremia.|DRUG: Long-treatment of any active antibiotic regimen 14 days of any active antibiotic treatment for uncomplicated enterococcal bacteremia.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Depression|Fatigue|Quality of Life
Interventions: DRUG: methylphenidate hydrochloride|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Administered With a Yellow Fever Vaccine in Adults
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: YF-17D|BIOLOGICAL: TDV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of an Intervention to Increase Diabetic Retinopathy Screening Attendance
Status: COMPLETED
Conditions: Diabetes|Retinopathy
Interventions: BEHAVIORAL: Training, audit, and reminders|BEHAVIORAL: Intervention after 6 months (wait list)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Complex decongestıve Therapy on oxıdatıve Stress and antıoxıdants
Status: ENROLLING_BY_INVITATION
Conditions: What Are the Effects of Lymphedema Treatment
Interventions: OTHER: Complex decongestive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Benefit of Functional Movement Control for Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Aerobic exercise & movement control|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Opiate Dependence
Interventions: DRUG: Tiagabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study Of Antimineralocorticoid Activity Of PF-03882845 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: 3 mg PF-03882845|DRUG: 10 mg PF-03882845|DRUG: 30 mg PF-03882845|DRUG: 100 mg PF-03882845|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of Tolcapone on Cognitive and Behavioral Dysfunction in Patients With BI and NCD
Status: UNKNOWN
Conditions: Brain Injuries, Traumatic|Neurocognitive Disorders|Brain Injuries
Interventions: DRUG: Tolcapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmias at Extreme Altitude
Status: RECRUITING
Conditions: Arrhythmias, Cardiac|Tachycardia, Ventricular|Tachycardia, Supraventricular|Bradycardia
Interventions: DIAGNOSTIC_TEST: Ambulatory rhythm recording
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Critical Lower Limb Ischemia
Interventions: DEVICE: SUNDANCE™ Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine Timing on Resistance Training Adaptations in College Athletes
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Creatine|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lowering Uric Acid in Live Kidney Donors
Status: COMPLETED
Conditions: Renal Transplant Donor of Left Kidney|Renal Transplant Donor of Right Kidney
Interventions: DRUG: Allopurinol 300 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab and Cetuximab With or Without Irinotecan in Treating Patients With Irinotecan-Refractory Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: BIOLOGICAL: cetuximab|BIOLOGICAL: bevacizumab|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of ASM-024 Administered to Healthy Subjects and Subjects With Moderate Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: ASM-024
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Management of Colorectal Cancer Patients Infected With COVID-19: a Multicenter Prospective Cohort Study.
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Timing of colorectal cancer surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of AAV1-gamma-sarcoglycan Gene Therapy for Limb Girdle Muscular Dystrophy Type 2C
Status: COMPLETED
Conditions: Limb Girdle Muscular Dystrophy Type 2C|Gamma-sarcoglycanopathy
Interventions: BIOLOGICAL: AAV1-gamma-sarcoglycan vector injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Left Ventricular Thrombosis|Anticoagulants and Bleeding Disorders
Interventions: DRUG: Apixaban Oral Tablet [Eliquis]|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy
Status: RECRUITING
Conditions: Lung Cancer
Interventions: PROCEDURE: Bronchoscopies|PROCEDURE: Sputum Sample|PROCEDURE: Venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Immune Response of a Rotavirus Vaccine in HIV-infected and Uninfected Children Born to HIV-infected Mothers
Status: COMPLETED
Conditions: HIV Infection|Rotavirus Infection
Interventions: BIOLOGICAL: RotaTeq|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Prognostic Factors in Frontline FCR for Patients With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Alopecia Areata of the Scalp With Intradermal Injections of Botulinum Toxin
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Intracutaneous injections of Botulinum Toxin A (Botox), 0.1 cc per injection site, which equals 10 units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auranofin in Treating Patients With Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer
Interventions: DRUG: auranofin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Sensorimotor training (SMT)|OTHER: Resistance training (RT)|OTHER: Control group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Immunosuppression
Interventions: DRUG: Tacrolimus|DRUG: Prednisone|DRUG: Mycophenolate mofetil|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata
Status: RECRUITING
Conditions: Areata Alopecia|Alopecia|Hypotrichosis|Hair Diseases|Skin Diseases|Pathological Conditions, Anatomical
Interventions: DRUG: Baricitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Air-polishing or Conventional Treatment
Status: COMPLETED
Conditions: Periodontitis|Adult Periodontitis
Interventions: PROCEDURE: Gracey curette.|PROCEDURE: Ultrasonic scaler.|PROCEDURE: Erythritol air-polishing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surprise Question in End of Life (SeQuEL) Care and the Effect of Prompting Palliative Care Consultation: End-Stage Liver Disease
Status: ENROLLING_BY_INVITATION
Conditions: End-Stage Liver Disease
Interventions: BEHAVIORAL: Prompted Palliative Care Consult
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
Status: UNKNOWN
Conditions: Central Nervous System Embryonal Neoplasm|Embryonal Tumor With Multilayered Rosettes, C19MC-Altered|Germ Cell Tumor|Medulloblastoma|Medulloepithelioma|Primitive Neuroectodermal Tumor|Recurrent Childhood Central Nervous System Embryonal Neoplasm|Recurrent Malignant Germ Cell Tumor|Recurrent Medulloblastoma|Recurrent Primitive Neuroectodermal Tumor
Interventions: DRUG: Carboplatin|DRUG: Mannitol|DRUG: Melphalan|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Sodium Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study
Status: COMPLETED
Conditions: Squamous Cell Carcinoma, Head And Neck|Squamous Cell Carcinoma Mouth|Squamous Cell Carcinoma of the Oral Cavity
Interventions: DRUG: Sitravatinib|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of rTMS of the Cerebellum on Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Transcranial Magnetic Stimulation
Interventions: DEVICE: sham rTMS|DEVICE: active rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula in Patients Undergoing Gastroscopy
Status: NOT_YET_RECRUITING
Conditions: Gastroscopy
Interventions: DEVICE: High Flow Nasal Cannula|DEVICE: Conventional Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pilot Trial on the Effect of a Probiotic Fermented Drink on Antibiotic-associated Diarrhea (AAD)
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: OTHER: probiotic dairy drink|OTHER: acidified milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lung Isolation in Thoracic Surgery - a Randomized Trial Comparing the VivaSight™ EB Endobronchial Blocker With Established Devices
Status: COMPLETED
Conditions: Lung Separation Techniques|One-Lung Ventilation
Interventions: DEVICE: Mallinckrodt™ Endobronchial Tube|DEVICE: Fuji Uniblocker™|DEVICE: ETView VivaSight™-SL+EB|DEVICE: COOK© Arndt Endobronchial Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Cushing Syndrome
Interventions: DRUG: relacorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Possible Effects of Apalutamide on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-Muscle Invasive Bladder Urothelial Carcinoma|Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma
Interventions: DRUG: Apalutamide|PROCEDURE: Biospecimen Collection|OTHER: Questionnaire Administration|PROCEDURE: Transurethral Resection of Bladder Tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Acral Vitiligo : Narrowband Ultraviolet-B and Microneedling With and Without Platelet Rich Plasma
Status: UNKNOWN
Conditions: Vitiligo
Interventions: COMBINATION_PRODUCT: microneedling and Platelet rich plasma|RADIATION: NB-UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT)
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: obeticholic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Combination Immunotherapy With NeuVax and Trastuzumab in High-risk HER2+ Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: NeuVax vaccine|DRUG: Trastuzumab|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Motivation-enhancing App to Retain Patients With Hay Fever in a Trial After Treatment
Status: UNKNOWN
Conditions: Grass Pollen Allergy|Rhinoconjunctivitis
Interventions: OTHER: Motivation-enhancing intervention|OTHER: Standard intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Guanfacine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Head-to-head Comparison of [68Ga]Ga-FAPI and [68Ga]Ga-TATE PET/CT in Patients With Nasopharyngeal Carcinoma: a Single-center, Prospective Study
Status: COMPLETED
Conditions: Tumor Positron-Emission Tomography
Interventions: DRUG: 68Ga-DOTATATE and 68Ga-FAPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preemptive Ketorolac for Shoulder Tip Pain During Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Ketorolac|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Incentive Spirometry With and Without Aerobic Exercises in Interstitial Lung Disease
Status: RECRUITING
Conditions: Interstitial Lung Disease
Interventions: DEVICE: incentive spirometer with aerobic exercises|DEVICE: incentive spirometry without aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors|Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors
Interventions: DRUG: 177Lu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Progesterone as a Treatment for Women Active Preterm Labor
Status: WITHDRAWN
Conditions: Labor, Premature
Interventions: DRUG: Vaginal progesterone gel|DRUG: Placebo vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Pain Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Acute Pain|Chronic Pain
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)
Status: TERMINATED
Conditions: Acute Pulmonary Edema
Interventions: DRUG: Midazolam|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Resynchronisation Therapy and AV Nodal Ablation Trial in Atrial Fibrillation Patients (CAAN-AF)
Status: COMPLETED
Conditions: Heart Failure|Atrial Fibrillation
Interventions: PROCEDURE: AV nodal ablation|DRUG: Medical Ventricular Rate Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Instrumentation Systems for the Treatment of Adolescent Scoliosis
Status: COMPLETED
Conditions: Scoliosis
Interventions: PROCEDURE: Moss Miami Spine Instrumentation System|PROCEDURE: Universal Spine Instrumentation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: ATLAS: Ambulatory Treatments for Leakage Associated With Stress
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Urinary Incontinence
Interventions: BEHAVIORAL: Behavioral Therapy|DEVICE: Intravaginal Pessary|DEVICE: Pessary combined with behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relaxing Effects of Acupuncture, Sham Acupuncture or no Acupuncture
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Genuine acupuncture (A)|DEVICE: Sham acupuncture (B)|OTHER: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia?
Status: COMPLETED
Conditions: Hypocalcemia|Thyroid Diseases
Interventions: DIETARY_SUPPLEMENT: Tums|DIETARY_SUPPLEMENT: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BAY94-9027 PK Study Comparing to Another Long Acting Product
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Damoctocog (Jivi, BAY94-9027)|DRUG: Elocta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Impact of the Impella CP Assist Device in Pts. With Cardiogenic Shock on the Patients Hemodynamic
Status: RECRUITING
Conditions: Cardiogenic Shock
Interventions: DEVICE: Impella CP microaxial pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC