pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study Evaluating Gemtuzumab Ozogamicin in Acute Myelogenous Leukemia After Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: Mylotarg (gemtuzumab ozogamicin) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Newborn Care Kit to Save Lives in GB, Pakistan
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Mortality|Omphalitis|Post-Partum Hemorrhage
Interventions: DEVICE: Integrated Newborn Care Kit (iNCK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Custirsen|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Eight-week Study to Evaluate the Efficacy and Safety of 2 Doses of Saredutant in Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety
Interventions: DRUG: Saredutant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of EDUcation Strategy on Patients With COLorectal CANCER or Advanced Adenoma in the Detection of Colorectal Cancer of Their First-degree Relatives
Status: COMPLETED
Conditions: Cancer Colorectal
Interventions: BEHAVIORAL: Therapeutic Education Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preoperative Localization of Infraclinical Breast Tumors: Isotopic Localization by iodine125 Seed Versus Standard Localization Using a Metal Wire
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Metal wire|DEVICE: Radioactive Iodine Seed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Herzuma-capecitabine/Cisplatin for Gastric Cancer
Status: UNKNOWN
Conditions: HER-2 Positive Gastric Cancer|Metastatic Cancer
Interventions: DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Rextriction Training in Upper Extremity of Elderly
Status: RECRUITING
Conditions: Exercise Training|Blood Flow Restriction Training|Geriatrics
Interventions: OTHER: Blood flow restriction (BFR) with low load resistance training|OTHER: Routine strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Intravenous Dose of E3112 in Japanese Healthy Adult Male Participants
Status: COMPLETED
Conditions: Healthy Male Participants
Interventions: DRUG: E3112|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Accuracy of the Preoperative Molecular Diagnosis of Uterine Tumors by Liquid Biopsy
Status: UNKNOWN
Conditions: Leiomyoma, Uterine|Leiomyosarcoma Uterus
Interventions: PROCEDURE: Collection of Leiomyoma samples|PROCEDURE: Collection of Leiomyosarcoma samples|PROCEDURE: Collection of control samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial Comparing Outcomes With Merocel Packing or Thrombin-JMI for Anterior Epistaxis
Status: TERMINATED
Conditions: Epistaxis
Interventions: DRUG: Thrombin-JMI|DRUG: Merocel pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin as Alternative to the Autologous Stem Cell Transplantation in Relapsed and Refractory Classical Hodgkin's Lymphoma (BASALT)
Status: UNKNOWN
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial
Status: WITHDRAWN
Conditions: Extensive Stage Lung Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|BIOLOGICAL: Durvalumab|DRUG: Etoposide|RADIATION: Hypofractionated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Absolute Bioavailability of GSK2118436 Following a Single Oral Dose Co-Administered With an Intravenous Radiolabelled Microtracer of GSK2118436 in Subjects With BRAF Mutant Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of Indinavir Plus Ritonavir in HIV-Positive Patients Failing Therapy With Amprenavir, Nelfinavir, or Saquinavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Occlusive and Classical Hypertrophy Training in Terms of Thickness and Stiffness of The Muscle
Status: COMPLETED
Conditions: Muscle Tightness|Hypertrophy|Occlusion Vein
Interventions: OTHER: Heavy hypertrophy training|OTHER: Light hypertrophy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Testing the Combination of Copanlisib, Nivolumab and Ipilimumab in Patients With Advanced Cancer and Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Copanlisib|PROCEDURE: Echocardiography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Intervention for Primary Caregivers to Improve Outcomes in Children With Severe Malnutrition
Status: COMPLETED
Conditions: Child Malnutrition
Interventions: BEHAVIORAL: Counseling Intervention Package|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nicotine Replacement for Smoking Cessation During Pregnancy
Status: COMPLETED
Conditions: Nicotine Dependence|Smoking Cessation
Interventions: DRUG: Nicotrol Inhaler|DRUG: Placebo Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MD1003 in Spinal Progressive Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: MD1003 100mg capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Intervention for Post-Covid Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Post Acute Sequelae of SARS-CoV-2
Interventions: DEVICE: Muse S™ Headband system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: Metformin and Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia
Status: TERMINATED
Conditions: T-cell Type Acute Leukemia-Precursor|T-lymphoblastic Lymphoma/Leukaemia
Interventions: DRUG: Isatuximab SAR650984|DRUG: dexamethasone|DRUG: dexamethasone|DRUG: acetaminophen|DRUG: ranitidine|DRUG: diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway and Pulmonary Vascular Endothelial Function in Healthy Smokers: Effect of Inhaled Glucocorticosteroid Treatment
Status: COMPLETED
Conditions: Smoking
Interventions: PROCEDURE: echocardiogram plus albuterol|PROCEDURE: airway blood flow plus albuterol|DRUG: Fluticasone propionate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: 3-dimensional Versus 2-dimensional Laparoscopy of Ovarian Cyst
Status: COMPLETED
Conditions: Laparoscopy
Interventions: PROCEDURE: 3D laparoscope|PROCEDURE: 2D laparoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Carcinoma
Interventions: DRUG: ribociclib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Tivozanib + paclitaxel|DRUG: Tivozanib + temsirolimus|DRUG: Tivozanib|DRUG: Tivozanib (AV-951)|DRUG: Tivozanib + capecitabine|DRUG: Tivo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0777 Gel Extrusion Module (GEM) in the Treatment of Outpatients With Generalized Anxiety Disorder (0777-019)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: MK0777|DRUG: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: triamcinolone acetonide (Kenalog)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Everolimus|DRUG: Everolimus placebo|DRUG: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Task Sharing in InGuinal hErnia Repair Between Surgeons and Non-surgeon Physicians
Status: NOT_YET_RECRUITING
Conditions: Inguinal Hernia
Interventions: OTHER: Mesh inguinal hernia repair performed by Non-Surgeon Physicians (NSP)|OTHER: Mesh inguinal hernia repair performed by fully trained surgeons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Water Exchange Versus Carbon Dioxide for Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Adenomas|Colorectal Polyps|Pain
Interventions: OTHER: Water exchange colonoscopy|OTHER: Carbon dioxide insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of ERCP Mechanical Simulator (EMS) Practice on Endoscopic Retrograde Cholangiopancreatography (ERCP) Training
Status: COMPLETED
Conditions: Training
Interventions: DEVICE: ERCP mechanical simulator practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy Combination With Anlotinib for Limited-stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: DRUG: Concurrent chemoradiotherapy plus anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR3680 in Combination With Docetaxel in the Treatment of mCRPC
Status: UNKNOWN
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: SHR3680+Docetaxel|DRUG: SHR3680|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IntraCranial Angiography-derived Fraction Flow-guided Percutaneous Transluminal Angioplasty and Stenting Versus Medical Therapy (ICAS-MT)
Status: NOT_YET_RECRUITING
Conditions: ICAS - Intracranial Atherosclerosis
Interventions: COMBINATION_PRODUCT: Stenting plus medical therapy|DRUG: Medical therapy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Action Observation Training in Older Adults.
Status: NOT_YET_RECRUITING
Conditions: Aging|Exercise
Interventions: PROCEDURE: Multicomponent exercise without action observation.|PROCEDURE: Multicomponent exercise associated with action observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PROOF Trial - Prospective, Open-label, Multicenter, Non-randomized Investigation on Percutaneous Patent Foramen Ovale (PFO) Closure Using the Occlutech PFO Occluder to Prevent Recurrence of Stroke in Patients With Cryptogenic Stroke and High Risk PFO
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|PFO - Patent Foramen Ovale
Interventions: DEVICE: Occlutech PFO Occluder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Community Reinforcement Approach and Family Training for Substance Use in Early Psychosis Intervention
Status: COMPLETED
Conditions: Psychosis|Schizophrenia and Related Disorders|Schizophrenia Spectrum and Other Psychotic Disorders|Substance Use|Substance Use Disorders
Interventions: BEHAVIORAL: Group-Based Community Reinforcement Approach and Family Training-Early Psychosis Intervention (CRAFT-EPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD
Status: ENROLLING_BY_INVITATION
Conditions: PTSD
Interventions: DEVICE: TMS|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Decision-Support Tool for Adult Consumers With Mental Health Needs and Their Care Managers
Status: COMPLETED
Conditions: Mental Disorders
Interventions: BEHAVIORAL: Moving Patient Outcomes toward Wellness and Recovery (mPOWR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiation Therapy, Temozolomide, and Erlotinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: CNS Tumor, Adult
Interventions: DRUG: erlotinib hydrochloride|DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descriptive Analysis of Morphological Aspects of Nerve by Ultra-high Frequency Ultrasound (30-50MHZ) in Demyelinating Neuropathies: Inflammatory Demyelinating Polyneuropathy Chronic (IPDC), Neuropathy Multifocal Motor Block of Conducting (NMMBC) and Neuropathy With Antibody A MAG
Status: COMPLETED
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: OTHER: Ultrasound UHF peripheral nerves|OTHER: Electro myography surface nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mycophenolate Mofetil in Membranous Nephropathy and Focal Segmental
Status: COMPLETED
Conditions: Glomerulonephritis, Membranous|Glomerulosclerosis, Focal
Interventions: DRUG: prednisolone and mycophenolate mofetil|DRUG: prednisolone and chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Neural Mobilization Techniques to Standard Care Treatment in Patients With Lumbar Radiculitis
Status: UNKNOWN
Conditions: Radiculitis
Interventions: OTHER: Neural Mobilization|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk
Status: NOT_YET_RECRUITING
Conditions: Primary Myelofibrosis|Myeloproliferative Neoplasm
Interventions: BIOLOGICAL: Ropeginterferon alfa-2b|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Empowered Strategy to Reduce Asthma Morbidity in Highly Impacted Populations; PeRson EmPowered Asthma RElief
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PARTICS using QVAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Soft Tissue Infections
Interventions: DRUG: Daptomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of In-111 Pentetreotide to Treat Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Indium-111 pentetreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DTaP-IPV-Hep B-PRP~T Combined Vaccine Versus DTaP-IPV//PRP~T Combined Vaccine + Hep B Vaccine in Hep B Primed Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Haemophilus Influenzae Type b Infection|Poliomyelitis|Hepatitis B
Interventions: BIOLOGICAL: DTaP-IPV-Hep B-PRP~T combined vaccine|BIOLOGICAL: DTaP-IPV//PRP~T and Hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TIVA and VIMA on Blood Glucose and Insulin Levels in Lung Lobectomy Patients
Status: COMPLETED
Conditions: Hyperglycemia Stress
Interventions: DRUG: TIVA|DRUG: VIMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Safety and Immunogenicity of HIV Vaccines in Healthy Volunteers
Status: COMPLETED
Conditions: Vaccine Response
Interventions: BIOLOGICAL: Ad4-mgag|BIOLOGICAL: Ad4-EnvC150|BIOLOGICAL: gp 120 Protein Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone
Status: TERMINATED
Conditions: Prostate Cancer|Metastatic Castrate-Resistant Prostate Cancer|PSA
Interventions: DRUG: OGX-427|DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Allergic Diseases in Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Diseases
Interventions: OTHER: Hydrolyzed Formula|OTHER: Control formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 Malocclusion
Status: COMPLETED
Conditions: Orthodontic Appliance Complication|Malocclusion, Angle Class II, Division 1
Interventions: DEVICE: Mini-implant-supported Twin-Block|DEVICE: Twin-Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PM8002 Plus Nab-paclitaxel as First Line Therapy for TNBC
Status: RECRUITING
Conditions: TNBC
Interventions: DRUG: PM8002|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propioceptive Neuromuscular Facilitation Vs Balance Exercise Along With Conventional Therapy for Balance and Gait in Chronic Parkinson's Patient
Status: UNKNOWN
Conditions: Parkinson
Interventions: DIAGNOSTIC_TEST: Propioceptive Neuromuscular Facilitation|DIAGNOSTIC_TEST: Balance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization
Status: RECRUITING
Conditions: Carotid Artery Diseases
Interventions: DEVICE: Carotid Artery Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eccentric Stretching in Patients With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Cold application+Deep friction+Home exercise+Eccentric stretching|OTHER: Cold application+Deep friction+Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Erlotinib (Tarceva) as Second-line Treatment in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer After Failure of Pemetrexed in First-line Therapy
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Insertion Technique for Laryngeal Mask Airway
Status: COMPLETED
Conditions: Airway Morbidity
Interventions: OTHER: Group 1 Classic|OTHER: Group 2 pre-inflated|OTHER: Group 3 ELL-PIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vaccines and Dietary Oats in the Treatment of Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Vaccine Vivotif + Vaccine Dukoral + oats|BIOLOGICAL: Vaccine Vivotif + Vaccine Dukoral|DIETARY_SUPPLEMENT: Oats|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of Multiple Ascending Doses and Food Effect of LV232 Capsules
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: LV232/Placebo|DRUG: LV232
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Supplements on the Prevention of Cachexia in Head and Neck Cancer Treated With Radio(Chemo)Therapy
Status: COMPLETED
Conditions: Cancer Cachexia|Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: BioMega SDA®|DIETARY_SUPPLEMENT: Sunflower oil high oleic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Research of S-1 Versus Pemetrexed in the Maintenance Treatment of Advanced NSNSCLC
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: S-1 therapy|DRUG: Pemetrexed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Vibratory Stimuli on Pain Perception Governing Infiltration Anesthesia in in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia, Local
Interventions: OTHER: Buccal and direct palatal injection with the aid of Buzzy|OTHER: Buccal and indirect palatal injection with the aid of Buzzy|OTHER: Buccal and direct palatal injection without Buzzy|OTHER: Buccal and indirect palatal injection without Buzzy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Memory Impairment
Interventions: DRUG: AZD8529|DRUG: Placebo to match AZD8529
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study
Status: COMPLETED
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: RVT-101 35 mg|DRUG: RVT-101 70 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients
Status: COMPLETED
Conditions: Opioid Dependence|Hepatitis|HIV
Interventions: OTHER: computerized Cognitive Behavioral Therapy (CBT)|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flow Controlled Ventilation (FCV) With the Evone Ventilator and Tritube Versus Volume Controlled Ventilation (VCV)
Status: COMPLETED
Conditions: Pulmonary Ventilation
Interventions: DEVICE: Aisys Carestation ventilator and normal endotracheal tube|DEVICE: Evone ventilator and Tritube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: OraVescent Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: gene therapy|BIOLOGICAL: interleukin-2 gene|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT)
Status: COMPLETED
Conditions: Cryptococcal Meningitis
Interventions: DRUG: MAT2203|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Nervous System Diseases|Brain Diseases|Cardiovascular Diseases|Vascular Diseases|Central Nervous System Diseases
Interventions: DEVICE: rTMS Contralesional M1|DEVICE: rTMS Contralesional PMC|DEVICE: rTMS Ipsilesional PMC|DEVICE: rTMS sham at Ipsilesional M1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Trial of Cyclosporine and Tacrolimus Therapy With Steroid Withdrawal in Living-Donor Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation|Living Donors
Interventions: DRUG: tacrolimus|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUALITY OF RECOVERY AFTER INTRAOPERATIVE MORPHINE OR METHADONE
Status: COMPLETED
Conditions: Pain, Postoperative|Nausea and Vomiting, Postoperative
Interventions: DRUG: Methadone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Melanoma DNA Vaccine Delivered by Electroporation
Status: COMPLETED
Conditions: Melanoma (Skin)|Intraocular Melanoma
Interventions: BIOLOGICAL: Xenogeneic Tyrosinase DNA Vaccine|DEVICE: TriGrid Delivery System for Intramuscular Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Low Locally Advanced Rectal Cancer With Radiotherapy Removal TNT Plus Neoadjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: CapeOX + cetuximab|DRUG: CapeOX + bevacizumab|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
Status: RECRUITING
Conditions: Neoplasms
Interventions: DRUG: TSR-022|DRUG: Nivolumab|DRUG: TSR-042|DRUG: TSR-033|DRUG: Docetaxel|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cipro® XR in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Cipro XR (Ciprofloxacin, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Melatonin in the Burning Mouth Syndrome
Status: UNKNOWN
Conditions: Sleep Disorders, Circadian Rhythm
Interventions: DRUG: Melatonin 3 mg|DRUG: Placebo Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
Status: COMPLETED
Conditions: Alagille Syndrome|Cholestasis|Biliary Atresia
Interventions: DRUG: magnesium gluconate|DRUG: magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of a Perioperative Smoking Cessation Program on Smoking Cessation/Reduction and Perioperative Complications
Status: COMPLETED
Conditions: Smoking|Tobacco Use
Interventions: OTHER: Smoking cessation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: entrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Impact of Two Methods of Continuous Veno-venous Hemodiafiltration on Time Nursing Work in Intensive Care
Status: WITHDRAWN
Conditions: Acute Renal Failure
Interventions: PROCEDURE: Continuous veno-venous haemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT
Status: UNKNOWN
Conditions: Chronic Graft-versus-host-disease|Leukemia Relapse
Interventions: DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
Status: WITHDRAWN
Conditions: Breast Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|Lymphoma|Sarcoma
Interventions: DRUG: Carvedilol|DRUG: Lisinopril|DRUG: Pravastatin|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Understanding the Mechanisms of Diastolic Dysfunction
Status: WITHDRAWN
Conditions: Heart Failure With Preserved Ejection Fraction|Healthy
Interventions: DIAGNOSTIC_TEST: MRI (cardiac) off-label use gadolinium contrast (IND exempt)|DIAGNOSTIC_TEST: MRI (cardiac)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine
Status: COMPLETED
Conditions: Menstrually Associated Migraine
Interventions: DRUG: Frovatriptan|DRUG: Frovatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study of SB681323 and Prednisolone on Biomarkers in COPD (Chronic Obstructive Pulmonary Disease) Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: SB681323|DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: VIR-2218 and peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-5475 in Participants With Hypoxemia Due to COVID-19 Pneumonia (MK-5475-009)
Status: WITHDRAWN
Conditions: Coronavirus Disease 2019 (COVID-19)|Pneumonia|Hypoxemia
Interventions: DRUG: MK-5475|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Poliglumex and Capecitabine in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: paclitaxel poliglumex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)
Status: TERMINATED
Conditions: Hypercholesterolemia, Familial|Lipid Metabolism, Inborn Errors
Interventions: DRUG: Comparator: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Hybrid SPECT-CT With Labeled Leukocytes for Diagnosis of Vascular Prosthesis Infections
Status: UNKNOWN
Conditions: Vascular Prosthesis Infection
Interventions: BIOLOGICAL: 99mTc-Exametazime (HMPAO)-labeled leukocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Echocardiography-guided Percutaneous Septal Radiofrequency Ablation for Obstructive HCM After Alcohol Septal Ablation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: Percutaneous Intramyocardial Septal Radiofrequency Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens
Status: UNKNOWN
Conditions: Female Breast Cancer|Male Breast Cancer
Interventions: PROCEDURE: Bilateral mastectomy|OTHER: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Efficacy and Safety of Edoxaban on Prevention of Catheter-related Thrombosis (CRT) in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Thrombosis, Venous|Cancer|Catheter Complications
Interventions: DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Frequent Follow up on Compliance in Patients Receiving PAP Therapy Due to OSA (Pap: Positive Airway Pressure, OSA: Obstructive Sleep Apnea )
Status: COMPLETED
Conditions: Patient Compliance|Sleep Disorder|Obstructive Sleep Apnea of Adult
Interventions: OTHER: study group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Perennial Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: pine cone extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study of Atomoxetine in the Treatment of Mild to Moderate Cognitive Difficulties in Menopausal Women
Status: COMPLETED
Conditions: Menopause|Cognitive Disturbances
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D and Omega-3 on Cerebrovascular Disease
Status: COMPLETED
Conditions: Stroke|Vitamin D
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DRUG: Fish oil|DIETARY_SUPPLEMENT: Vitamin D placebo|DRUG: Fish oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PHOENIX Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) Administered After Liver Transplantation for Hepatitis C.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]|DRUG: Copegus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: Placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes From Home in Patients Recovering From Major Gynecologic Cancer Surgery: Measuring Symptoms and Health-related Quality of Life
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cancer|Uterine Cancer|Vaginal Cancer|Vulvar Cancer
Interventions: BEHAVIORAL: online platform WEBCORE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI System
Status: COMPLETED
Conditions: Open Angle Glaucoma|Normal Tension Glaucoma|Healthy
Interventions: DIAGNOSTIC_TEST: LASER SPECKLE FLOWGRAPHY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iConquerFear Program for the Treatment of Fear of Cancer Recurrence in Patients With Localized Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: OTHER: Internet-Based Intervention - Complete iConquerFear program|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of EGF816 and Gefitinib in TKI-naïve EGFR-mutant Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: EGF816|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: OVA BiP peptide|BIOLOGICAL: gp209-2M antigen|BIOLOGICAL: recombinant 70-kD heat-shock protein|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Escitalopram|DRUG: Wellbutrin XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Gingival Crevicular Fluid microRNAs on Orthodontic Tooth Movement
Status: COMPLETED
Conditions: Orthodontic Tooth Movement
Interventions: DEVICE: Elastomeric powerchain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Infection|Oral Complications
Interventions: DRUG: fluconazole|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neurovegetative Decoupling in Somatoform Disorders : Biofeedback Interest
Status: RECRUITING
Conditions: Somatoform Disorders|Irritable Bowel Syndrome|Psychogenic Non-Epileptic Seizure
Interventions: BEHAVIORAL: Heart rate variability Biofeedback [HRV-BFB]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating The Safety And Efficacy Of PF-03049423 In Subjects With Ischemic Stroke
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: PF-03049423|DRUG: PF-03049423|DRUG: PF-03049423|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S9915 Triacetyluridine, Fluorouracil, and Leucovorin in Treating Patients With Unresectable, Locally Advanced, or Metastatic Cancer of the Esophagus or Stomach
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: triacetyluridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis
Status: RECRUITING
Conditions: Peri-Implantitis|Peri-Implant Health
Interventions: PROCEDURE: Non-surgical peri-implant therapy|PROCEDURE: Implantoplasty|PROCEDURE: Erythritol Air-abrasive device|PROCEDURE: Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serological Response to Porcine Circovirus Type 1 (PCV-1) and PCV-1 DNA in Stools of Infants Following Administration of Rotarix™
Status: COMPLETED
Conditions: Rotavirus Infection|Evidence of PCV-1 Replication and/or Immune Response to the PCV-1 in HRV Vaccinated Infants
Interventions: PROCEDURE: Stool sample|PROCEDURE: Serum sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p