pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™ Embolic Agent
Status: COMPLETED
Conditions: Leiomyoma|Leiomyomatosis|Uterine Neoplasms
Interventions: DEVICE: Uterine fibroid embolization BeadBlock™|DEVICE: Uterine fibroid embolization Embosphere®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic Patients
Status: TERMINATED
Conditions: Cirrhosis
Interventions: DRUG: Orphenadrine|DRUG: Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medium-term Follow-up of Patients With Obstetric Antiphospholipid Syndrome: MRI Study of White Matter
Status: COMPLETED
Conditions: Antiphospholipid Syndrome
Interventions: PROCEDURE: Diffusion tensor imaging MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
Status: RECRUITING
Conditions: Pediatric Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: Panzyga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Long-Term Safety of Vumerity and Tecfidera in Participants With Multiple Sclerosis (MS)
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Diroximel Fumarate|DRUG: Dimethyl Fumarate|DRUG: Disease-Modifying Therapies (DMTs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness, Safety, and Cost Efficacy of Water (H2O) as a Substitute for Sodium Bicarbonate (NaHCO3) Plus Solution in Neutralization of Chemical Peeling Using 35% Glycolic Acid Solution
Status: COMPLETED
Conditions: Skin Manifestations
Interventions: OTHER: Sodium Bicarbonate (NaHCO3) Plus Solution|OTHER: Water (H2o)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Wound Drainage After Knee or Hip Arthroplasty
Status: WITHDRAWN
Conditions: Complications; Arthroplasty
Interventions: DRUG: Rivaroxaban (Xarelto)|DRUG: Warfarin (Coumadin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antithymocyte Globulin and Cyclosporine in Treating Low Risk Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Antithymocyte globulin|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Liquid Formulation of ROTAVIN
Status: COMPLETED
Conditions: Diarrhea|Diarrhea Rotavirus
Interventions: BIOLOGICAL: ROTAVIN (liquid formulation)|BIOLOGICAL: ROTAVIN-M1 (frozen formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 5-day Defibrotide Treatment for Hepatic SOS/VOD
Status: UNKNOWN
Conditions: Sinusoidal Obstruction Syndrome|Veno-occlusive Disease|Bone Marrow Transplant Complications
Interventions: DRUG: Defibrotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenously or Subcutaneously Administered REGN3500 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN3500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: When is the Best Moment to Remove the Urinary Catheter After Laparoscopic Hysterectomy?
Status: COMPLETED
Conditions: Urinary Tract Infection|Bladder Retention
Interventions: DEVICE: Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of OCT1 on Metformin Tolerance
Status: COMPLETED
Conditions: Tolerance
Interventions: DRUG: Metformin|DRUG: Omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Interventional Study of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing AZD2014 vs Everolimus in Patients With Metastatic Renal Cancer
Status: TERMINATED
Conditions: Metastatic Clear Cell Renal Carcinoma
Interventions: DRUG: AZD2014|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harnessing Chronomodulation to Enhance Osteogenesis
Status: WITHDRAWN
Conditions: Tooth Loss
Interventions: DRUG: Group A - test:Tooth extraction and intake of NSAID and a non-NSAID|DRUG: Group B - Control 1: tooth extraction and intake of NSAID and a non-NSAID|DRUG: Group C - Control 2: tooth extraction and intake of a Non-Nsaid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids for Treating Adults With Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: EPA omega-3 fatty acid|DIETARY_SUPPLEMENT: DHA omega-3 fatty acid|DIETARY_SUPPLEMENT: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Exercise Program in Breast Cancer Patients With Joint Pain While Taking Aromatase Inhibitors.
Status: COMPLETED
Conditions: Women With ER Positive Breast Cancer Taking (AI) w Joint Discomfort and Stiffness
Interventions: OTHER: Arm A Directed exercise program|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dasatinib in Patients With Imatinib Resistant or Intolerant Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine Cardiomyopathy: Response to Cyclic GMP PDE5 Inhibitors in Acromegaly Cardiomyopathy
Status: COMPLETED
Conditions: Acromegaly Cardiomyopathy
Interventions: DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder
Status: TERMINATED
Conditions: Depression
Interventions: DRUG: Armodafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human Thrombin for Bleeding During Surgery
Status: COMPLETED
Conditions: Surgical Hemostasis
Interventions: BIOLOGICAL: rThrombin|DRUG: bovine thrombin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Tretinoin Gel Microsphere, 0.1% and RETIN-A MICRO ® Gel Microsphere, 0.1% in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tretinoin Gel Microsphere, 0.1%|DRUG: RETIN-A MICRO® (Tretinoin) Gel Microsphere, 0.1%|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maximal Use Systemic Exposure (MUSE) Study of Levulan Kerastick
Status: COMPLETED
Conditions: Keratosis, Actinic
Interventions: DRUG: Aminolevulinic Acid (ALA)|DEVICE: BLU-U
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety Study of Xyotax to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Paclitaxel polyglumex (Xyotax)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Audiovisual Aids in the Preanesthetic Interview
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: BEHAVIORAL: questionnaire|BEHAVIORAL: face-to-face interview|BEHAVIORAL: brochure|BEHAVIORAL: movie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme Inhibitors
Status: UNKNOWN
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: DRUG: Equivalent dose enalapril|DRUG: Equivalent dose lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Lateral Glide Along With Thoracic Mobilizations in Patients With Neurogenic Cervicobrachial Pain.
Status: COMPLETED
Conditions: Cervicobrachial Syndrome
Interventions: OTHER: cervical lateral glide|OTHER: thoracic mobilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Neonatal Markers for the Development of Neurosensorial Sequelae in Children Infected by Cytomegalovirus in Utero
Status: COMPLETED
Conditions: Congenital Cytomegalovirus Infection
Interventions: OTHER: detection of CMV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of FTD/TPI (Lonsurf) in Metastatic Breast Cancers With or Without Prior Exposure to Fluoropyrimidines (LONBRECA)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Cohort A|DRUG: Cohort B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROCRIT (Epoetin Alfa) 60,000 Units Administered Once Every Two Weeks in Anemic Cancer Patients Who Are Not Receiving Chemotherapy or Radiation Therapy
Status: COMPLETED
Conditions: Anemia|Neoplasms
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Simplified Geriatric Evaluation Performed by Oncologists Prior to Cancer Treatment by Radiotherapy or Chemotherapy in Subjects Aged 70 Years or Older With Inoperable Squamous Cell Cancer of the Head and Neck
Status: UNKNOWN
Conditions: Inoperable Squamous Cell Cancer of the Head and Neck
Interventions: OTHER: Geriatric Screening Test G8|OTHER: Geriatric fragility test GERICO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Two-part Study to Compare a Tablet and Capsule Formulation of GSK2838232 With and Without Food, and to Assess the Safety and Drug Levels of Repeated Once-daily Doses of GSK2838232 Without Ritonavir
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: GSK2838232 100 mg tablet|DRUG: GSK2838232 50 mg capsule|DRUG: Ritonavir 100 mg tablets|DRUG: Placebo for GSK2838232 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Subcutaneously-administered Avonex (Interferon Beta-1a) in Multiple Sclerosis (MS) Patients
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: BG9418 (interferon beta 1-a)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Lung Approach Versus Conventional Protective Ventilation in Obese Patients Undergoing Open Abdominal Surgery
Status: COMPLETED
Conditions: Abdominal Surgery|Obese Patients
Interventions: OTHER: ARM|OTHER: spontanous ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients
Status: TERMINATED
Conditions: Gastrointestinal Cancer|Rectal Cancer
Interventions: DRUG: Procrit (epoetin alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiac Arrest|Anoxic Encephalopathy|Status Epilepticus
Interventions: DRUG: Anti-epileptic drugs|OTHER: No anti-epileptic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy
Status: RECRUITING
Conditions: Supratentorial Brain Tumor
Interventions: DRUG: Ibuprofen 800 Mg in 8 mL INTRAVENOUS INJECTION [Caldolor]|PROCEDURE: Scalp nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Decalcification of the Aortic Valve by Vitamin K2 (Menaquinone-7)
Status: UNKNOWN
Conditions: Aortic Valve Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin K2 (Menaquinone 7) + Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli Seed Extract and Skin Health
Status: COMPLETED
Conditions: Skin Inflammation
Interventions: DIETARY_SUPPLEMENT: Broccoli, mustard, vitamin C|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Chewing Gum in Influencing Capsule Endoscopy Transit Time
Status: COMPLETED
Conditions: Gastric Transit Time|Small-bowel Transit Time
Interventions: OTHER: Chewing Gum|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: DNA Analysis of Tumor Tissue From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA methylation analysis|GENETIC: comparative genomic hybridization|GENETIC: fluorescence in situ hybridization|GENETIC: microarray analysis|GENETIC: polymerase chain reaction|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: DRUG: TOL2506|DRUG: Tamoxifen|DRUG: Letrozole tablets|DRUG: Anastrozole Tablets|DRUG: Exemestane Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Scapular Stabilization Exercises Combined With Post Facilitation Stretch in Patients With Upper Cross Syndrome: A Randomized Control Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Upper Cross Syndrome
Interventions: PROCEDURE: Electrotherapy and physical agents|PROCEDURE: Post Facilitation Stretch|PROCEDURE: Scapular Stabilization Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Trial Comparing Triple Therapy Guided by the PCR Detection of Clarithromycin Resistance vs Empiric Concomitant Quadruple Therapy for Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: H Pylori Infection Eradication|Antibiotics Therapeutic Strategies|H Pylori Eradication
Interventions: OTHER: Quadruple concomitant therapy treatment|OTHER: Triple therapy guided by the result of the molecular resistance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Breathing Exercises and Virtual Reality Applications During Pregnancy and Labor.
Status: COMPLETED
Conditions: Labor Pain|Labor Onset|Patient Satisfaction|Virtual Reality|Breathing; Tic
Interventions: OTHER: Breathing Exercise|OTHER: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Manual Lymphatic Drainage on Postoperative Edema of the Face and the Neck After Orthognathic Surgery
Status: COMPLETED
Conditions: Maxillofacial Abnormalities|Post Procedural Discharge
Interventions: OTHER: Manual Lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diastolic Dysfunction
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell Tumors
Status: COMPLETED
Conditions: Testicular Cancer
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Melphalan|DRUG: Carboplatin|DRUG: Mesna|DRUG: Ifosfamide|DRUG: Etoposide|PROCEDURE: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute, Synergistic Effects of Protein and Calcium on Appetite and Energy Intake
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Porridge-based breakfast.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.
Status: RECRUITING
Conditions: Phenylketonurias
Interventions: DIETARY_SUPPLEMENT: PKU GOLIKE|DIETARY_SUPPLEMENT: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Eflornithine and Bicalutamide Compared With Eflornithine Alone, Bicalutamide Alone, and No Neoadjuvant Therapy in Treating Patients With Localized Prostate Cancer Undergoing Brachytherapy or Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|DRUG: eflornithine|DRUG: oral eflornithine placebo|DRUG: oral bicalutamide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Diffusion MRI for Non-invasive Lesion Detection and Therapy Follow-up: Study With Patients With Ovarian Cancer and Peritoneal Metastasis
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Metastasis
Interventions: PROCEDURE: intravenous contrast administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Controlled Study of Chain Blanket for Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DEVICE: Weighted metal chain blanket|DEVICE: Control plastic chain blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Treatment for Hypereosinophilic Syndrome
Status: COMPLETED
Conditions: Eosinophilia|Hypereosinophilic Syndrome|Leukocyte Disorder|Hematologic Diseases
Interventions: DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Darbepoetin Alfa (Aranesp®) on Anemia in Patients With Advanced Hormone Independent Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms|Anemia
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the Prevention of Chronic or Episodic Migraine
Status: ACTIVE_NOT_RECRUITING
Conditions: Episodic Migraine|Chronic Migraine
Interventions: DRUG: Atogepant 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung|Brain Neoplasms
Interventions: DRUG: Bevacizumab plus erlotinib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
Status: COMPLETED
Conditions: Total Fluid Volume Increased
Interventions: DRUG: Hydroxyethyl Starch|DRUG: Lactate Ringers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: HEPLISAV-B® in Adults With End-Stage Renal Disease (ESRD) Undergoing Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease on Hemodialysis (Diagnosis)
Interventions: DRUG: HEPLISAV-B®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome
Status: COMPLETED
Conditions: Psoriasis|Metabolic Syndrome
Interventions: DRUG: Secukinumab|BEHAVIORAL: Life-style intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin|DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma|Marginal Zone Lymphoma|Indolent Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: axicabtagene ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 Infection
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Estetrol monohydrate 15 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Relational Problems
Interventions: DRUG: Oxytocin nasal spray|BEHAVIORAL: Brief Cognitive-Behavioral Conjoint Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: DRUG: cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prophylaxis of Gastrointestinal Bleeding in Cirrhotic Patients Using THALIDOMIDE
Status: WITHDRAWN
Conditions: Gastrointestinal Hemorrhage|Portal Hypertension
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Melphalan for Use With the Hepatic Delivery System Treatment in Patients With Unresectable Hepatocellular Carcinoma or Intra Hepatic Cholangiocarcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma
Interventions: DEVICE: Delcath Hepatic Delivery System|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Proportion of Human Epidermal Growth Factor Receptor 2 Protein Overexpression of Gastric Adenocarcinoma and Prognostic Effect of HER2, and Analysis of Practice Pattern of Herceptin Use in Stage IV Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Individualized Plan for Improving Adherence to Portable Oxygen Therapy in Patients With Respiratory Pathology
Status: COMPLETED
Conditions: COPD|ILD|Dyspnea
Interventions: BEHAVIORAL: Educational and Training with counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Wuling Powder in Treating Metabolic Syndrome of Spleen Deficiency and Dampness
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DRUG: Wulingsan single decoction granules|DRUG: Wulingsan co-decoction granules|DRUG: Wuling Powder|DRUG: Wulingsan granule simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Performed Pterygium Surgery Study
Status: WITHDRAWN
Conditions: Pterygium of Conjunctiva and Cornea
Interventions: DRUG: 5-Fluorouracil|DRUG: Bevacizumab|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategic Treatment and Assessment for Youth (STAY)
Status: NOT_YET_RECRUITING
Conditions: Depression in Adolescence|Suicide Prevention
Interventions: BEHAVIORAL: Strategic Treatment Assessment for Youth (STAY)|BEHAVIORAL: Measurement Based Care As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Sublingual Spray on Vitamin D3 Levels in the Blood Compared to Other Forms of Vitamin D3
Status: COMPLETED
Conditions: Vitamin D3 Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D substitution with sublingual sprayable microemulsion.|DIETARY_SUPPLEMENT: Vitamin D substitution with oil droplets|DIETARY_SUPPLEMENT: Vitamin D substitution with capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mobilization With Movement in Patients With Osteoarthritis of the Hip
Status: COMPLETED
Conditions: Osteoarthritis Hip|Joint Disease|Musculoskeletal Diseases|Pathologic Processes
Interventions: OTHER: Real mobilization-with-movement (MWM)|OTHER: Sham mobilization-with-movement (MWM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increased Knowledge Improve Oral Hygiene In Patients With Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: BEHAVIORAL: Periodontal health education session|BEHAVIORAL: Oral hygiene motivation session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PHYSICAL ACTIVITY AND FVIII CLEARANCE: RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A (PHYSEMO)
Status: UNKNOWN
Conditions: Hemophilia A
Interventions: DEVICE: SenseWear® armband device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy of Cervical Core Exercises in Persons With Temporomandibular Joint Dysfunction
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: Rocabado Exercises|OTHER: Servical Core Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lobaplation or Cisplatin in Adjuvant Chemotherapy for Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Lobaplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Caloric Restriction and Resveratrol in the Sirtuin System in Women and Men Aged 55 to 65 Years
Status: COMPLETED
Conditions: Vascular System Injuries|Lipid Metabolism Disorders|Endothelial Disfunction
Interventions: DRUG: Resveratrol|BEHAVIORAL: Caloric restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study in Young Adults the Meningococcal Serogroup C Vaccine Produced by Bio-Manguinhos
Status: COMPLETED
Conditions: Meningitis, Meningococcal, Serogroup C
Interventions: BIOLOGICAL: 'MenCC-Bio'|BIOLOGICAL: MENJUGATE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Transjugular Intrahepatic Portosystemic Shunt on Oxygenation in Cirrhotic Patients With Hepatopulmonary Syndrome
Status: COMPLETED
Conditions: Hepatopulmonary Syndrome
Interventions: PROCEDURE: Transjugular intrahepatic portosystemic shunt
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of GSK1550188 in Japanese Subjects With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GSK1550188 1mg/kg or 10mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Fitness Using a Kinect Interventional System
Status: COMPLETED
Conditions: Virtual Reality|Physical Fitness
Interventions: OTHER: Kinect intervention system combined with aerobic exercise training|OTHER: aerobic dance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Intermittent Oral Dosing of ASP1517 in ESA-untreated Chronic Kidney Disease Patients With Anemia
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication
Status: RECRUITING
Conditions: Multiple Sclerosis|Poststroke/CVA Hemiparesis|Parkinson Disease|Amputation|Knee Impairment
Interventions: OTHER: Pathologic group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photodynamic Therapy With Porfimer Sodium in Treating Patients With Precancerous Lesions, Cancer, or Other Disease of the Aerodigestive Tract
Status: COMPLETED
Conditions: Head and Neck Cancer|Precancerous/Nonmalignant Condition
Interventions: DRUG: Porfimer Sodium|PROCEDURE: Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of GW679769 On Sleep Onset And Maintenance,And Next Day Functioning In The Elderly And Non-elderly With Primary Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Insomnia
Interventions: DRUG: GW679769
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypnofertility for Women Undergoing In Vitro Fertilization (HWUIVF)
Status: COMPLETED
Conditions: Infertility Unexplained|Fertility Disorders
Interventions: BEHAVIORAL: Interventions Based on Hypnofertility|OTHER: Routine clinical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)
Status: RECRUITING
Conditions: Social Isolation|SCD|Subjective Cognitive Decline|MCI|Mild Cognitive Impairment|AD|Alzheimer Disease
Interventions: BEHAVIORAL: social isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract Cancers
Status: COMPLETED
Conditions: Biliary Tract Cancer|Gallbladder Cancer|Cholangiocarcinoma|Ampullary Cancer
Interventions: OTHER: Active Symptom Control|DRUG: L-folinic acid|DRUG: 5 FU|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Li-Fraumeni Syndrome Imaging Study
Status: ENROLLING_BY_INVITATION
Conditions: Li-Fraumeni Syndrome
Interventions: DIAGNOSTIC_TEST: Whole body STIR MRI|DIAGNOSTIC_TEST: DW-MRI|DIAGNOSTIC_TEST: PET-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exposure Therapy For Veterans With PTSD And Panic Attacks
Status: COMPLETED
Conditions: PTSD|Panic Attacks
Interventions: BEHAVIORAL: Multiple Channel Exposure Therapy - Veterans|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: n3 PUFA and Muscle-disuse Atrophy in Young Women
Status: COMPLETED
Conditions: Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: n3 PUFA-enriched fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bicalutamide Implants (Biolen) With Radiation Therapy in Patients With Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: bicalutamide|RADIATION: Stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Efficacy of Anti-Aging Treatment Regimen in Subjects With Photodamage
Status: COMPLETED
Conditions: Skin Manifestations
Interventions: OTHER: Three Product Anti-Aging Treatment Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Monocenter, Cross-sectional Study to Compare Different Type of Cognitive Impairment in Multiple Sclerosis Patients and Cerebrospinal Fluid Biomarkers (Beta Amyloid, Total Tau Protein and Tau-phosphorylated Protein).
Status: TERMINATED
Conditions: Disseminated Sclerosis
Interventions: OTHER: Cognitive impairment of multiple sclerosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Immune Monitoring of Prevalent Kidney Transplant Recipients Using Torque Teno Virus: A Single-Center, Prospective Cohort Study
Status: RECRUITING
Conditions: Kidney Transplant Infection|Kidney Transplant Rejection|Kidney Transplant; Complications
Interventions: OTHER: Torque teno virus DNA measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Pancreatic Enzyme Supplements (Pancrelipase) for Treating Pain in Patients With Chronic Pancreatitis
Status: WITHDRAWN
Conditions: Pancreatitis
Interventions: DRUG: Pancrelipase|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of a New Drug to Treat Overactive Bladder vs. Placebo
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Oxybutynin topical gel|OTHER: Placebo topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Minimum Effective Concentration of Ropivacaine in Ultrasound-guided Supraclavicular Block
Status: COMPLETED
Conditions: Minimum Effective Concentration of Local Anesthetic
Interventions: OTHER: brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of LY3462817 in Healthy Japanese and Non-Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3462817 (SC)|DRUG: Placebo (SC)|DRUG: LY3462817 (IV)|DRUG: Placebo (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab)
Status: RECRUITING
Conditions: Myeloma|Lymphoma|Leukemia
Interventions: DRUG: Tocilizumab before CAR-T cell infusion|DRUG: Tocilizumab at emerging CRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Study on Performance of the Ponto Implant System Using Minimally Invasive Ponto Surgery (in Adult Patients)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss
Interventions: OTHER: Abbreviated Profile Hearing Aid Benefit (APHAB)|OTHER: Glasgow Benefit Inventory (GBI)|OTHER: Additional follow-up visit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body
Status: NOT_YET_RECRUITING
Conditions: Non-transfusion Dependent Beta-thalassemia (NTDT)
Interventions: DRUG: REGN7999|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nalbuphine as an Adjuvant to Local Anaesthetic Mixture in Peribulbar Cataract Surgery
Status: COMPLETED
Conditions: Nalbuphine as an Adjuvant to L. A in Peribulbar Block for Cataract Surgery
Interventions: DRUG: Nalbuphine|DRUG: lidocaine, bupivacaine, hyaluronidase , saline|DRUG: lidocaine, bupivacaine , hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test the Blood Concentration of 4 Padsevonil Product Variants and the Effect of Food on Padsevonil
Status: WITHDRAWN
Conditions: Healthy Participants|Epilepsy
Interventions: DRUG: Padsevonil type 1 Tablet 200 mg|DRUG: Padsevonil type 2 Tablet|DRUG: Padsevonil type 3 Tablet|DRUG: Padsevonil type 4 Tablet|DRUG: Padsevonil type 5 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Partial-Thickness Rotator Cuff Tears
Status: TERMINATED
Conditions: Arthroscopic Surgical Treatment of High-grade (>50%) Partialthickness
Interventions: DEVICE: REGENETEN™ Bioinductive Implant|DEVICE: Arthroscopic repair of the high-grade (>50%) partialthickness
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Iron Versus Oral Iron Plus a Web-based Behavioral Intervention in Young Children (IRONCHILD)
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Iron-deficiency
Interventions: DRUG: Ferrous Sulfate|BEHAVIORAL: IRONCHILD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
Status: COMPLETED
Conditions: Obesity|Overweight|Overweight and Obesity|PreDiabetes|Type 2 Diabetes|Type 2 Diabetes Mellitus|Type 2 Diabetes Mellitus in Obese
Interventions: BEHAVIORAL: Physical Activity Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ibandronate (Boniva) to Evaluate Satisfaction in Women With Post-Menopausal Osteoporosis or Osteopenia
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Intravascular Hypothermia Therapy in Acute Ischemic Stroke Patients
Status: UNKNOWN
Conditions: Hypothermia|Reperfusion Injury|Ischemic Stroke|Thrombectomy
Interventions: DEVICE: ZOLL Intravascular Temperature Management system, Quattro catheter|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Xeloda (Capecitabine) in Combination With Chemotherapy in Patients With Advanced and/or Metastatic Gastric Cancer.
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Cisplatin|DRUG: Capecitabine|DRUG: Epirubicin|DRUG: Cisplatin|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tripterygium Wilfordii in Patients With Lupus Nephritis
Status: UNKNOWN
Conditions: Nephritis, Lupus
Interventions: DRUG: Tripterygium wilfordii Hook F|DRUG: Cyclophosphamide|DRUG: GC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy
Status: RECRUITING
Conditions: Hepatic Ischemia
Interventions: DRUG: sodium bicarbonate Ringer's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia in Children and Adolescents After the Ravitch Procedure and Thoracotomy
Status: COMPLETED
Conditions: Pain, Postoperative|Surgery, Thoracic
Interventions: DRUG: Ropivacaine/Fentanyl|DRUG: Bupivacaine/Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Horizontal vs. Vertical Positioning of the iCare Rebound Tonometer and Effects on Intraocular Pressure Readings
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: OTHER: Horizontal iCare|OTHER: Vertical iCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improve the Comfort, Safety and Quality of Upper Endoscopy by a Modified Fasting Protocol
Status: COMPLETED
Conditions: Gastroscopy|Feelings|Fasting
Interventions: OTHER: Modified Fasting Group|OTHER: Conventional Fasting Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH