pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder
Status: RECRUITING
Conditions: Feeding and Eating Disorders
Interventions: BEHAVIORAL: Enhanced Cognitive-behavior therapy for adolescents with an eating disorder|BEHAVIORAL: Family-based therapy for adolescents with an eating disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accu-Chek missiOn: SMBG in Patients With diAbetes on inSulin Study (COMPASS) - Multiple Center, Open, and Non-randomized Study
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DEVICE: Accu-Chek Integra Glucometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodality Treatment for Patients With Resectable Non-Small Cell Lung Cancer (NSCLC) - BEACON Study: Bevacizumab and Chemotherapy for Operable NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Pre-surgical Treatment with Bevacizumab plus Chemotherapy|DRUG: Pre-Surgical Docetaxel and Cisplatin and Adjuvant Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: SKB264|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of rhuMAb Beta7 in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: placebo|DRUG: rhuMAb Beta7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pentoxifylline and Alpha Lipoic Acid in PCOS Resistant to Clomiphene Citrate
Status: COMPLETED
Conditions: Clomiphene Citrate|Resistant Ovary Syndrome|Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Alpha lipoic acid (ALA)|DRUG: Pentoxifylline (PTX)|DRUG: Clomiphene Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracolumbar Interfascial Plane Block Versus Bilateral Erector Spinae Plane Block In Lumbar Laminectomy
Status: UNKNOWN
Conditions: Postoperative Pain|Lumbar Laminectomy|Thoracolumbar Interfascial Plane Block|Erector Spinae Plane Block|Ultrasound
Interventions: PROCEDURE: Thoracolumbar Interfascial Plane Block (TLIP)|PROCEDURE: Bilateral Erector Spinae plane Block (ESB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Music and Relaxing Light on the Patient's Anxiety After Cardiac Surgery in the Intensive Care Unit
Status: UNKNOWN
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result|Anxiety|Pain, Postoperative|Delirium
Interventions: OTHER: relaxation session combining music and soft light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) Receiving Vedolizumab in Real-World Practice in Poland
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Disease (IBD)|Crohn's Disease|Ulcerative Colitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endovascular vs Conservative Treatment in Patients With Chronic Subdural Hematomas and Mild Symptoms
Status: NOT_YET_RECRUITING
Conditions: Subdural Hematoma, Chronic
Interventions: DEVICE: embolization of the middle meningeal artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Trial of Atomoxetine to Evaluate Academic Outcome in Children Ages 8-11 Years With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Machine Learning to Detect Risky Behavior in Psychiatric Clinics
Status: NOT_YET_RECRUITING
Conditions: Machine Learning|Dangerous Behavior
Interventions: OTHER: Detecting Risky Behaviors and Providing a Safe Environment in Patients Receiving Inpatient Treatment in a Psychiatric Clinic Using Machine Learning Model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells
Status: COMPLETED
Conditions: β Thalassemia Major
Interventions: BIOLOGICAL: γ-globin reactivated autologous hematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lancashire Objective Volume Evaluation of Leg Oedema in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Heartfelt device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study to Evaluate PRO-169 for Diabetic Macular Edema
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Lucentis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5093151 and RO5027838 in Patients With Type 2 Diabetes Mellitus on a Stable Dose of Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: RO5027838|DRUG: RO5027838|DRUG: RO5093151|DRUG: RO5093151
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Function in Elderly Postoperative Patients
Status: COMPLETED
Conditions: Rehabilitation Strategies for Elderly Post-Operative Patients
Interventions: BEHAVIORAL: Resistance training|BEHAVIORAL: Neuromuscular electrical stimulation of the quadriceps muscle|BEHAVIORAL: Standard rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant SLOT Versus SOX in Patients With Locally Advanced, Resectable Gastric/Esophagogastric Junction (EGJ) Cancer
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Docetaxel;oxaliplatin;s1|DRUG: oxaliplatin;s1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride, Docetaxel, and Radiation Therapy in Treating Patients With Uterine Sarcoma That Has Been Removed By Surgery
Status: TERMINATED
Conditions: Stage IA Uterine Sarcoma|Stage IB Uterine Sarcoma|Stage IC Uterine Sarcoma|Stage IIA Uterine Sarcoma|Stage IIB Uterine Sarcoma|Stage IIIA Uterine Sarcoma|Stage IIIB Uterine Sarcoma|Stage IIIC Uterine Sarcoma|Stage IVA Uterine Sarcoma|Stage IVB Uterine Sarcoma|Uterine Corpus Leiomyosarcoma
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Docetaxel|RADIATION: Internal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGN-CD228A in Advanced Solid Tumors
Status: TERMINATED
Conditions: Cutaneous Melanoma|Pleural Mesothelioma|HER2 Negative Breast Neoplasms|Non-small Cell Lung Cancer|Colorectal Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: SGN-CD228A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Different Meningitis Vaccine Formulations in Adolescents and Young Adults
Status: COMPLETED
Conditions: Invasive Meningococcal Disease
Interventions: BIOLOGICAL: Meningococcal (groups A, C, W, Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine + OMV.|BIOLOGICAL: Meningococcal (group B) multicomponent recombinant adsorbed vaccine plus OMV.|BIOLOGICAL: Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine.|BIOLOGICAL: Meningococcal (groups A, C, W, Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine + qOMV.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Premedication Trial for Tracheal Intubation of the NEOnate
Status: COMPLETED
Conditions: Premedication|Endotracheal Intubation
Interventions: DRUG: atropine+ propofol|DRUG: atropine + atracurium + sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring and Virtual Collaborative Care For Hypertension Control To Prevent Cognitive Decline
Status: COMPLETED
Conditions: Hypertension|Cognitive Decline
Interventions: OTHER: Virtual Collaborative Care Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Home-based Ergonomic Intervention Program in Caregivers of Chronic Post-stroke Patients
Status: COMPLETED
Conditions: Stroke|Quality of Life
Interventions: OTHER: Ergonomic intervention|OTHER: Postural plus kinesiotherapy intervention program|OTHER: Control or conservative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-PD1-antibody and Pulsed HHI for Advanced BCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Cemiplimab Injection [Libtayo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of TIVA by Closed Loop Anaesthesia Delivery System Versus Target Controlled Infusion Device
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Propofol|DRUG: Propofol|DRUG: Propofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)
Status: RECRUITING
Conditions: Advanced Melanoma
Interventions: BIOLOGICAL: Vusolimogene Oderparepvec|BIOLOGICAL: Nivolumab|BIOLOGICAL: Nivolumab + Relatlimab|BIOLOGICAL: Pembrolizumab|DRUG: Single-agent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advance Care Planning in the Emergency Department
Status: COMPLETED
Conditions: Congestive Heart Failure|Metastatic Cancer|Chronic Kidney Disease Requiring Chronic Dialysis|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: ED GOAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Faricimab (RO6867461; RG7716) for Extended Durability in the Treatment of Neovascular Age Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascularization, Choroidal|Macular Degeneration, Age-Related
Interventions: DRUG: Faricimab|DRUG: Ranibizumab|DRUG: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kronos Early Estrogen Prevention Study (KEEPS)
Status: UNKNOWN
Conditions: Menopause|Arteriosclerosis
Interventions: DRUG: Conjugated equine estrogens 0.45 mg/day|DRUG: Transdermal estradiol, 50 mcg/day|DRUG: Micronized progesterone, 200 mg/day x 12 d/month|DRUG: CEE , progesterone, estradiol patch or placebo for each|DRUG: CEE, progesterone, transdermal patch or the placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Three-Part Program for Parents With Premature Infants
Status: COMPLETED
Conditions: Premature Birth
Interventions: BEHAVIORAL: Psychoeducational video|BEHAVIORAL: Infant massage|BEHAVIORAL: Brazelton Neonatal Behavioral Assessment Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.
Status: COMPLETED
Conditions: Uncomplicated Plasmodium Falciparum Malaria
Interventions: DRUG: Artefenomel 800mg: piperaquine 640mg|DRUG: Artefenomel 800mg: piperaquine 960mg|DRUG: Artefenomel 800mg: piperaquine 1440mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medico-ecological Monitoring ((CSM, MCTQ, SPAQ, PSQI, HRV, Spirometry; Anthropometry, BP) of the Different Population Groups (Students, Schoolchildren, Volunteers) in North Caucasus
Status: UNKNOWN
Conditions: Conditionally Healthy Persons|Persons With a High Body Mass Index
Interventions: DEVICE: Heart Rate Variability|DEVICE: Spirometry|BEHAVIORAL: Testing of psycho-physiological functions using four questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra- And Inter-operator Reliability Of Isometric Back And Abdominal Muscle Strength Testing In Healthy Controls And Persons With Nonspecific Chronic Low Back Pain.
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Biodex-assisted isometric strength testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of SARS-Cov-2 in the Setting of a Non-dedicated COVID-19 Hospital in a Low CoV-2 Incidence Area: Implications for Surgery
Status: COMPLETED
Conditions: Covid19|Surgery|SARS (Severe Acute Respiratory Syndrome)
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 Ab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effects of Aerobic and Resistive Exercises in Female Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Exercise|Exercise Therapy
Interventions: OTHER: Aerobic Exercises|OTHER: Resistive Exercises|OTHER: Range of Motion Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Results of 8 Strand Repair of Flexor Tendon Injuries
Status: NOT_YET_RECRUITING
Conditions: Cut Flexor Zone ll Using 8-strand
Interventions: PROCEDURE: Repair of flexor tendon injury zone ll using 8- strand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiviral Activity of Peg-IFN-Alpha-2A in Chronic HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Pegylated Interferon-alpha 2a, 180 mcg/week sc|DRUG: Pegylated Interferon-alpha 2a, 90 mcg/week sc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Sedation Score and Bispectral Index for Induction in Geriatric Patients
Status: RECRUITING
Conditions: E03.155.253|Bispectral Index Monitor|Hypotension
Interventions: PROCEDURE: urological surgical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of MAZ-101 in the Treatment of Persistent Allergic Rhinitis (PER)
Status: NOT_YET_RECRUITING
Conditions: Allergic Rhinitis
Interventions: DRUG: MAZ-101association|DRUG: DYMISTA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TCM Daoyin Therapy in Individuals At-risk for COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Lung Diseases, Obstructive
Interventions: BEHAVIORAL: TCM Daoyin|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen Compared With Thalidomide in Treating Women With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer|Stage III Ovarian Epithelial Cancer|Stage IV Ovarian Epithelial Cancer
Interventions: DRUG: tamoxifen citrate|DRUG: thalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-adhesion Barrier on the Voice Quality After Thyroidectomy.
Status: UNKNOWN
Conditions: Thyroid Nodule|Thyroid Cancer|Voice Disorders
Interventions: DEVICE: Anti-adhesion barrier (Collarbarrier)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: DEVICE: TRE vs. NBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Ulcer Foot|Ulcer Healing|Diabetic Foot Ulcer|Non-healing Wound|Wound of Skin|Wound; Foot|Tissue Injury
Interventions: PROCEDURE: Standard of Care|OTHER: DermGEN™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Low Dose IL-2 and Ganciclovir in Cytomegalovirus Infection
Status: UNKNOWN
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Low-dose IL-2 and ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Neratinib|DRUG: QBS10072S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Patients With Pulmonary Sarcoidosis
Status: COMPLETED
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: ACZ885|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Personalized Rehabilitation Program of Facial Involvement in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis|Face|Facial Involvement|Rehabilitation
Interventions: PROCEDURE: Personalized rehabilitation program of facial involvement in systemic sclerosis|OTHER: Delivery of a standard prescription for facial rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related Bleeding
Status: TERMINATED
Conditions: Menorrhagia|Uterine Fibroids
Interventions: DEVICE: Doppler-Guided Uterine Artery Occlusion Device (DUAO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of AmBisome and DKF-5122
Status: COMPLETED
Conditions: Invasive Fungal Infections|Neutropenic Fever
Interventions: DRUG: AmBisome|DRUG: DKF-5122
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Metformin|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: PEG-asparaginase|DRUG: Doxorubicin|DRUG: Intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 (Delanzomib) in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: CEP-18770
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Sleep Deprivation and Changes in Cortical and Hippocampal Volume
Status: NOT_YET_RECRUITING
Conditions: Sleep Deprivation|Hippocampal Atrophy|Cortical Irregularity
Interventions: DIAGNOSTIC_TEST: Cerebral Nuclear Magnetic Resonance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lipo-dox and Cyclophosphamide /5-Fluorouracil in Patients With Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Lipo-Dox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study in Healthy Subjects to Assess How Dosing of Rifampin Affects What the Body Does to a Dose of GW679769 (Casopitant).
Status: COMPLETED
Conditions: Nausea and Vomiting, Chemotherapy-Induced
Interventions: DRUG: GW679769 (Casopitant) oral tablets|DRUG: Rifampin oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: ecallantide|DRUG: Phosphate Buffer Saline (PBS),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Guided Imagery Based on the Health Promotion Model on the Quality of Life in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: OTHER: training and counseling supported guided imagery application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Authorization Observational Study to Evaluate Cognition and Fatigue in Relapsing-remitting Multiple Sclerosis (RRMS) Patients Treated With Rebif®
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Rebif (Interferon beta-1a)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DRIHNC - Dehydration Reduction in Head & Neck Cancer
Status: COMPLETED
Conditions: Dehydration|Head & Neck Cancer|Esophageal Cancer
Interventions: DIETARY_SUPPLEMENT: Gatorade G2|DIETARY_SUPPLEMENT: Standard of care nutritional support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Social Network Interventions in Rural Honduras
Status: COMPLETED
Conditions: Malnutrition|Dysentery|Social Transmission of Health Behaviors
Interventions: BEHAVIORAL: exposure to vitamin use|BEHAVIORAL: exposure to water chlorination|BEHAVIORAL: high in-degree|BEHAVIORAL: nominated by random
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Of Outcome Of Lactose Free Formula Milk With Yogurt In Children With Acute Diarrhea
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: DIETARY_SUPPLEMENT: YOGURT|DIETARY_SUPPLEMENT: LACTOSE FREE FORMULA MILK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ambrisentan on Exercise Capacity in Fontan Patients
Status: COMPLETED
Conditions: Single Ventricle Fontan Palliation
Interventions: DRUG: Ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Extremities Rehabilitation Training System for Sarcopenic Hospitalized Aged 80+ Years
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: BEHAVIORAL: Motor-Assisted and Active Resistive Upper/Lower Extremities Rehabilitation Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Knee Joint Loading by Real-time Biofeedback Stair Walking Rehabilitation for Patients With MCKOA
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Laboratory-based gait retraining (LGR)|BEHAVIORAL: Sensor-based gait retraining (SGR)|BEHAVIORAL: Walking exercise control (Ctrl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Spectra Optia PMN Cell Collection Procedure
Status: COMPLETED
Conditions: Granulocyte/ Polymorphonuclear Cells
Interventions: DEVICE: Granulocyte/Polymorphonuclear Cell Collection (COBE Spectra System)|DEVICE: Granulocyte/Polymorphonuclear Cell Collection (Spectra Optia System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Anthocyanins Extracted From Purple Potatoes on Healthy Study Subjects' Postprandial Glycemia and Insulinemia
Status: COMPLETED
Conditions: Postprandial Glycemia
Interventions: OTHER: Dietary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual Reality (VR) Based Mindfulness Practice in Relieving Stress in Postgraduate Students
Status: NOT_YET_RECRUITING
Conditions: Student|Stress|Virtual Reality|Mindfulness
Interventions: OTHER: Virtual reality-supported mindfulness|OTHER: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study in Second Line Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Ramucirumab|BIOLOGICAL: Placebo|DRUG: Irinotecan|DRUG: Folinic Acid|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Laser Photobiomodulation Pulpotomy of Primary Molars in Children
Status: RECRUITING
Conditions: Pulpitis|Pulpotomy
Interventions: DEVICE: Photobiomodulation|DRUG: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Transcatheter aortic valve implantation|PROCEDURE: Surgical aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Press Tack Needle Acupuncture in Treating Lactation Insufficiency
Status: COMPLETED
Conditions: Lactation; Insufficient, Partial|Hypogalactia, Without Mention of Attachment Difficulty
Interventions: DEVICE: Press Tack Needle Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Percutaneous Angioplasty in Ischemic Leg Ulcer Healing
Status: COMPLETED
Conditions: Ischemic Foot Ulcers
Interventions: PROCEDURE: Percutaneous transluminal angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Face Masks on Pulmonary Function in Patients With COPD
Status: RECRUITING
Conditions: COPD|Walking, Difficulty
Interventions: DIAGNOSTIC_TEST: 6 Minute Walking Test|DIAGNOSTIC_TEST: Blood gas analysis|PROCEDURE: Wearing a Surgical Facemask|PROCEDURE: Wearing a FFP2- Facemask|PROCEDURE: Wearing no Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Cobimetinib Administered in Combination With Niraparib, With or Without Atezolizumab to Patients With Advanced Platinum-sensitive Ovarian Cancer
Status: COMPLETED
Conditions: OVARIAN CANCER
Interventions: DRUG: Cobimetinib|DRUG: Niraparib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Adverse Events and How Oral ABBV-552 Capsules Moves Through the Body of Healthy Adult Japanese and Han Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-552
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label NK Cell Infusion (FATE-NK100) With Subq IL-2 in Adults With AML
Status: COMPLETED
Conditions: Refractory Acute Myelogenous Leukemia|Relapsed Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: FATE-NK100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery
Status: NOT_YET_RECRUITING
Conditions: Delirium, Postoperative|Anesthesia|Surgery-Complications|Cognition Disorder|Delirium|Cognitive Decline
Interventions: BEHAVIORAL: Depth of anesthesia titration using pEEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pre Post Evaluation of Temperature, Steps, and Glucose With Additional Time Spent Outdoors in an Urban and Rural Setting
Status: COMPLETED
Conditions: Temperature|Exercise|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: 30 minutes outdoors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics/ Pharmacodynamics and Safety of DA-4001 in Healthy Male Subjects With Androgenic Alopecia
Status: COMPLETED
Conditions: Androgenic Alopecia
Interventions: DRUG: DA-4001 H|DRUG: DA-4001 L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation
Status: COMPLETED
Conditions: Critical Illness|Respiration, Artificial
Interventions: PROCEDURE: Non-sedation for intubated, mechanically ventilated patients|PROCEDURE: Controlgroup, sedation with daily wake-up trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tanespimycin (KOS-953) in Patients With Multiple Myeloma in First Relapse
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Tanespimycin|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Performance Assessment of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Metastatic Triple Negative Breast Cancer Patients
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: 89Zr-TLX250 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Satisfaction Regarding Home Healthcare Provider (HHP) Management of Type 1 Diabetic Patients Using a Closed-loop Automatic Insulin Delivery System
Status: COMPLETED
Conditions: Diabetes type1
Interventions: DEVICE: any closed-loop automatic insulin delivery system (or artificial pancreas) CE-marking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Nitroglycerin Ointment on Mastectomy Flap Necrosis
Status: COMPLETED
Conditions: Mastectomy Flap Necrosis
Interventions: DRUG: nitroglycerin ointment|DRUG: Polysporin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Trial of a Candidate PCV13 in Healthy People
Status: RECRUITING
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine|BIOLOGICAL: 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing ABX-CBL (Monoclonal Antibody) Versus Atgam in Patients With Steroid Resistant Acute Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft Vs Host Disease
Interventions: DRUG: ABX-CBL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Study of the Bioavailability of Brexpiprazole Orally Disintegrating Tablets in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Adult Male
Interventions: DRUG: OPC-34712
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premedication for ERCP With Midazolam or Tramadol
Status: COMPLETED
Conditions: Chronic Disease
Interventions: DRUG: Tramadol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Comparison the Treatment Effect Between Gastric Bypass and Exenatide in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: Gastric Bypass|DRUG: Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase 2 Trial of Pre-chemotherapy Leukine vs. Leukine-Dexamethasone in Combination With Gemzar & 5-FU in Patients With Metastatic Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Leukine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Latissimus Dorsi Tendon Transfer or Partial Arthroscopic Repair of Massive Rotator Cuff Tears
Status: UNKNOWN
Conditions: Full Thickness Rotator Cuff Tear
Interventions: PROCEDURE: Latissimus dorsi tendon transfer|PROCEDURE: Arthroscopic repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Repeated Loading Dose of Clopidogrel and High Dose of Clopidogrel Continuous Therapy on the Platelet Aggregation Inhibition in Patients With Myocardial Infarction Undergoing Interventional Treatment.
Status: WITHDRAWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Evaluation of Fostemsavir + (OBT) in HIV-1 Infected Children and Adolescents Who Are Failing Their cART and Have Dual- or Triple-class Antiretroviral Resistance
Status: RECRUITING
Conditions: HIV Infections With Multi Drug Resistant Virus
Interventions: DRUG: Fostemsavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Carboplatin-Based Chemotherapy in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: bevacizumab [Avastin]|DRUG: Carboplatin-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Immunonutrition on Inflamatory Markers After Bariatric Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|DIETARY_SUPPLEMENT: Balanced high-protein formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Alcohol Dependence|Alcoholism|Anxiety Disorder
Interventions: DRUG: Pexacerfont|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Cannabidiol Effect on Blood Pressure in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Cannabidiol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Neoadjuvant Chemoimmunotherapy|Fertility Preservation
Interventions: DRUG: Camrelizumab|DRUG: Cisplatin|DRUG: Nab paclitaxel|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Topical Antiviral Agents for Labial Cold Sores (Herpes Labialis)
Status: UNKNOWN
Conditions: Reccurent Herpes Labialis
Interventions: DRUG: Acyclovir 5%|DRUG: Docosanol 10%|DEVICE: Superlysine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study Utilizing Circulating Cell Free DNA (cfDNA) Use in the Detection of RAS Mutations in Patients With Advanced Colorectal Cancer.
Status: UNKNOWN
Conditions: Colon Cancer
Interventions: DRUG: investigator choice re-challenge with anti EGFR Rx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulant Therapy During Pacemaker Implantation
Status: COMPLETED
Conditions: Hemorrhage|Thrombosis|Embolism
Interventions: DRUG: Warfarin|DRUG: Aspirin|DEVICE: Permanent pacemaker|DEVICE: Implantable Cardioverter-defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: omalizumab|DRUG: omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of an Online Stepwise Therapeutic Device Based on a Cognitive-behavioral Approach for Cancer Patients With Insomnia
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Insomnia
Interventions: OTHER: Self screening|OTHER: Phone call|OTHER: Online questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Wheeze Detection in Adults During Dynamic Bronchial Situations Measured by PulmoTrack® 2010 With WIM-PC™ Technologies Recording
Status: UNKNOWN
Conditions: Asthma, Bronchial
Interventions: DEVICE: PulmoTrack® 2010 with WIM-PC™ Technologies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VAC Regimen for AML Patients Who Failed to Response to VA Regimen
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: chidamide in combination with venetoclax and azacitidine (VAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Borderline Ovarian Mucinous Tumor|Ovarian Mucinous Cystadenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Stage IA Fallopian Tube Cancer AJCC v6 and v7|Stage IA Ovarian Cancer AJCC v6 and v7|Stage IB Fallopian Tube Cancer AJCC v6 and v7|Stage IB Ovarian Cancer AJCC v6 and v7|Stage IC Fallopian Tube Cancer AJCC v6 and v7|Stage IC Ovarian Cancer AJCC v6 and v7|Stage IIA Fallopian Tube Cancer AJCC v6 and v7|Stage IIA Ovarian Cancer AJCC V6 and v7|Stage IIB Fallopian Tube Cancer AJCC v6 and v7|Stage IIB Ovarian Cancer AJCC v6 and v7|Stage IIC Fallopian Tube Cancer AJCC v6 and v7|Stage IIC Ovarian Cancer AJCC v6 and v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Oxaliplatin|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress and Oxysterols Profiling in Patients With Carotid Revascularization
Status: COMPLETED
Conditions: Carotid Stenosis|Cardiovascular Disease|Atherosclerosis|Stroke
Interventions: DRUG: Aspirin|DRUG: aspirin plus dipyridamole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase II Multicenter Study of Chemotherapy Versus Chemotherapy Plus Durvalumab (MEDI 4736) in Patients With Lymph Node Positive Urothelial Carcinoma of the Bladder
Status: RECRUITING
Conditions: Urothelial Carcinoma|Bladder Cancer
Interventions: OTHER: Abiraterone acetate|DRUG: Durvalumab|DRUG: Methotrexate|DRUG: Vinblastine|DRUG: Doxorubicin Hydrochloride|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial To Determine The Efficacy And Safety Of Insulin Eye Drops In Dry Eye In Patients With Topical Hypotensors
Status: RECRUITING
Conditions: Dry Eye|Glaucoma
Interventions: DRUG: Insulin|DRUG: Artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Health-related Quality of Life and Masticatory Function After Using Denture Adhesive and Denture Liner
Status: COMPLETED
Conditions: Complete Denture|Complete Edentulism
Interventions: DRUG: denture adhesive (Polident®, GlaxoSmithKline, Ireland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Olokizumab|DRUG: Omeprazole|DRUG: Caffeine|DRUG: Warfarin+ Vitamin K|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT