pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Three Different Loading Doses of Clopidogrel, in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Clopidogrel 300 mg|DRUG: Clopidogrel 600 mg|DRUG: Clopidogrel 900 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascending Single Doses of Erenumab (AMG 334) in Healthy Adults and Migraine Patients
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of ESP Block to SSN Block for Analgesia in Shoulder Surgery
Status: COMPLETED
Conditions: Arthroscopic Shoulder Surgery
Interventions: OTHER: Block procedures for shoulder surgery analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Methylprednisolone Combined Electric-acupuncture on Cognitive Function
Status: UNKNOWN
Conditions: Postoperative Complication|Cognitive Retention Disorder
Interventions: DRUG: Methylprednisolone|OTHER: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dual Antiplatelet Therapy in Patients With Aspirin Resistance Following Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Coronary Artery Disease|Aspirin Resistance
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home-based Cycling for People With Lumbar Spinal Stenosis
Status: NOT_YET_RECRUITING
Conditions: Symptomatic Lumbar Spinal Stenosis
Interventions: OTHER: Home-based cycling program|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tramadol in Penial Block Does it Improve Efficiency of Postoperative Analgesia in Circumcision
Status: COMPLETED
Conditions: Tramadol - Anesthetics- Child - Circumcision
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immunological Effects From Intranasal Chitin Micro-Particles
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Chitin Micro Particle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Acute Myeloid (AML)
Interventions: DRUG: gilteritinib|DRUG: LoDAC (Low Dose Cytarabine)|DRUG: Azacitidine|DRUG: MEC (Mitoxantrone, Etoposide, Cytarabine)|DRUG: FLAG-IDA (Granulocyte-Colony Stimulating Factor (G-CSF), Fludarabine, Cytarabine, Idarubicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Blood PRessure Control in Patients With Acute Type B AortIc Dissection
Status: UNKNOWN
Conditions: Blood High Pressure|Aortic Dissection Type B
Interventions: DRUG: Urapidil Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Programmed Death Ligand-1 (PD-L1) Expression in Cytological Versus Histological Lung Cancer Specimens
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Carcinoma, Small Cell
Interventions: DIAGNOSTIC_TEST: PD-L1 Immunocytochemistry (ICC)|DIAGNOSTIC_TEST: PD-L1 Immunohistochemistry (IHC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Superior Vena Cava Collapsibility Index for Predicting Fluid Responsiveness During High-risk Non-cardiac Surgery
Status: RECRUITING
Conditions: Surgery|Fluid Responsiveness|Transesophageal Echocardiography
Interventions: DIAGNOSTIC_TEST: Superior vena cava collapsibility index|OTHER: PEEP elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of the Association of Clotrimazole and Metronidazole in the Treatment of Vaginal Discharge From Different Etiologies.
Status: WITHDRAWN
Conditions: Sexual Active Women|Vaginal Discharge
Interventions: DRUG: Clotrimazole + Metronidazole|DRUG: Metronidazole|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Learning Self-hypnosis for Patients Awaiting Lung Transplantation
Status: TERMINATED
Conditions: Lung Diseases
Interventions: BEHAVIORAL: Self-hypnosis|PROCEDURE: Lung transplantation|OTHER: Standard post-operative pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-Cost Imaging for Cervical Cancer Prevention in the Texas Lower Rio Grande Valley
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasms of Female Genital Organs
Interventions: DRUG: Proflavine|PROCEDURE: High-Resolution Microendoscopy (HRME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Immunotherapy Combined With Neoadjuvant Therapy Versus Neoadjuvant Therapy for Breast Cancer
Status: UNKNOWN
Conditions: Stage II-III Breast Cancer
Interventions: DRUG: cytotoxic chemotherapy (docetaxel or epirubicin or cyclophosphamide or carboplatin)|DRUG: anti-Her2 monoclonal antibody (Trastuzumab, Pertuzumab)|DRUG: traditional herbal medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arm-crank Exercise Training on Cardiovascular Function of Patients With Peripheral Artery Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Intermittent Claudication|Hypertension
Interventions: OTHER: Arm ergometer|OTHER: Treadmill ergometer|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize Diclofenac's Plasma and Knee Exposure After Application of Diclofenac Gel to the Knee of Subjects With Osteoarthritis That Have a Scheduled Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac Diethylamine (DDEA) gel|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Thalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.
Status: COMPLETED
Conditions: Familial Hemiplegic Migraine
Interventions: DRUG: CGRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: A Study Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Subjects.
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: DRUG: HSK3486|DRUG: Propofol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose-Rate Brachytherapy
Status: RECRUITING
Conditions: Patients With Prostate Cancer
Interventions: PROCEDURE: MRI Guided Needles to deliver HDR Brachytherapy|PROCEDURE: MRI Guided Needles to deliver HDR Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: SGT-003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study
Status: NOT_YET_RECRUITING
Conditions: Induction of Labor Affected Fetus / Newborn|Pregnancy Late
Interventions: DRUG: Misoprostol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Interaction of Darapladib and CYP 3A4 in Healthy Subjects
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Darapladib|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery
Status: COMPLETED
Conditions: Acute Pain Following Decompressive Lumbar Spinal Surgery
Interventions: DRUG: Intrathecal Morphine|DRUG: Intrathecal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Bendamustine|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim-sndz|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Rituximab|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Covered Stents Versus Bare Metal Stents for Endovascular Treatment of Chronic Ischemia Mesenteric Disease.
Status: COMPLETED
Conditions: Chronic Mesenteric Ischemia|Stent Stenosis
Interventions: PROCEDURE: endovascular angioplasty using covered stents|PROCEDURE: endovascular angioplasty using bare metal stents|DEVICE: Duplex-scan|DEVICE: computerized tomography scan (CT-scan)|DEVICE: digital angiography|OTHER: Short Form-36 (SF-36) questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belgian Real Life Non-interventional Study (NIS) on Xarelto in Non-valvular Atrial Fibrillation (AF) Patients Treated for the Prevention of Stroke and Systemic Embolism
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: DIAGNOSTIC_TEST: Pharyngeal width measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Ultrasound (EUS) Artificial Intelligence Model for Normal Mediastinal and Abdominal Strictures Assessment
Status: UNKNOWN
Conditions: Abdomen|Mediastinum|Anatomic Abnormality|Strictures
Interventions: DIAGNOSTIC_TEST: Identification or discharge visualization of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos by an expert endoscopist|DIAGNOSTIC_TEST: Recognition of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos using artificial intelligence (AI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Music Therapy in Mental Subhealth (EMTMS)
Status: RECRUITING
Conditions: Depression, Anxiety
Interventions: DEVICE: The mini apps named "SOUL GYM" on the Wechat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single- Versus Multiple-dose Antimicrobial Prophylaxis for The Prevention of Infectious Complications Associated With Peroral Endoscopic Myotomy(POEM) for Achalasia
Status: UNKNOWN
Conditions: Esophageal Achalasia
Interventions: DRUG: Saline Solution|DRUG: Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Active Versus Passive Lower Extremity Neural Mobilization in Lumber Radiculopathy
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Active neural mobilization|OTHER: passive neural mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter
Status: COMPLETED
Conditions: Pleural Effusion, Malignant
Interventions: OTHER: Standard Drainage Instructions|OTHER: Aggressive Drainage Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Thymus Size of Infants Who Born to COVID-19 Positive Mothers Associated With Neonatal Morbidities?
Status: UNKNOWN
Conditions: Covid19|Thymic Hypoplasia
Interventions: DIAGNOSTIC_TEST: chest x-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study Evaluating Stability of Fracture Segments After Treatment of Mandibular Angle Fracture With 3d Strut Plate With or Without IMMF.
Status: UNKNOWN
Conditions: Mandible Fracture
Interventions: PROCEDURE: 3d strut plate.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Polyphenols and Lipid Oxidation
Status: COMPLETED
Conditions: Obesity, Insulin Sensitivity, Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Comparison of different combinations of polyphenols with respect to effects on fat oxidation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Reduction Produced by Different Treatments in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Median nerve neural mobilization|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Modified With Conventional Adaptive Servoventilation Processes
Status: COMPLETED
Conditions: Periodic Breathing|Cheyne-Stokes Respiration
Interventions: DEVICE: Adaptive Servo-controlled Ventilation (ASV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of the the Timed 360° Turn Test
Status: COMPLETED
Conditions: Cerebral Palsy|Gait, Spastic|Gait Disorders in Children|Diplegic Cerebral Palsy|Hemiplegic Cerebral Palsy
Interventions: OTHER: assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Docetaxel, Cetuximab and Cisplatin Followed by Radiation, Cetuximab and Cisplatin in Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Cetuximab|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Administration of Levobupivacaine and Opioids in Elderly
Status: COMPLETED
Conditions: Adverse Reaction to Spinal Anesthetic
Interventions: DRUG: The impact of 10 independent variables on the likelihood of not developing hypotension after intrathecal injection.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Efficacy and Safety of Rituximab Biosimilar HLX01 and Rituximab in Combination With CHOP, in Previously Untreated Subjects With CD20+ DLBCL
Status: COMPLETED
Conditions: B-cell Non Hodgkin's Lymphoma
Interventions: DRUG: HLX01|DRUG: Rituximab|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial to Study the Safety and Immunogenicity of Pneumovax™ 23 (V110) in Participants From the Russian Population (V110-018)
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: Pneumovax™ 23
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ibrutinib + Venetoclax in Untreated WM
Status: ACTIVE_NOT_RECRUITING
Conditions: Waldenstrom Macroglobulinemia|MYD88 Gene Mutation
Interventions: DRUG: IBRUTINIB|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma|Liver Cancer|Adrenal Cancer
Interventions: RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Assessment of Cervicocerebral Vessels to Improve the Brain Injury for CAGB Patients (IACV Study)
Status: RECRUITING
Conditions: Coronary Disease|Coronary Artery Bypass|Strokes Thrombotic
Interventions: OTHER: Integrated Assessment of Cervicocerebral Vessels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of Epworth Richmond's Echocardiography Education Focused Year
Status: COMPLETED
Conditions: Shock, Cardiogenic|Cardiac Tamponade|Pulmonary Embolism|Hypovolemia
Interventions: BEHAVIORAL: Epworth Richmond's Echocardiography Focused Year
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm|OTHER: Hospital-based mCIT|OTHER: Hospital-based TR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Health Benefits of Budesonide
Status: ACTIVE_NOT_RECRUITING
Conditions: Epigenetic Effects of Intranasal Steroids|Environmental Exposure
Interventions: DRUG: Budesonide Nasal|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intravenous Clonidine for Sedation in Infants and Children Who Are Mechanically Ventilated - Dosing Finding Study
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: DRUG: intermittent IV CLON
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GVH 022P: Study Using Anti Tumor Necrosis Factor Antibody (Infliximab) for Treatment of Acute Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Analyse Difference in Bioavailability Between MP29-02 and Fluticasone Propionate
Status: WITHDRAWN
Conditions: Bioavailability Study
Interventions: DRUG: MP29-02|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Operative Pain Control Following Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: OTHER: Tylenol and NSAIDS (Ibuprofen, diclofenac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oraxol and Pembrolizumab in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Oraxol|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome-Directed Food for Sustained Recovery From Acute Malnutrition
Status: NOT_YET_RECRUITING
Conditions: Acute Malnutrition With no Complications
Interventions: DIETARY_SUPPLEMENT: Microbiome-directed food - MAM|DIETARY_SUPPLEMENT: Ready-to-use supplementary food (RUSF)|DIETARY_SUPPLEMENT: Microbiome-directed food (MDF) - SAM|DIETARY_SUPPLEMENT: Ready-to-use therapeutic food (RUTF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Topical Instillation for Open Abdomen in the Septic Patients With Complicated Intra-abdominal Infections
Status: COMPLETED
Conditions: Wound Infection
Interventions: DEVICE: Continuous topical triple-tube irrigation and suction|DEVICE: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Prosthesis Rotaio (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse
Status: UNKNOWN
Conditions: Intervertebral Disc Displacement
Interventions: DEVICE: Anterior cervical discectomy with prosthetic disc replacement / ESP.|DEVICE: Anterior cervical discectomy with prosthetic disc replacement / Rotaio.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patogenic Mutation in 5 Genes
Status: COMPLETED
Conditions: Colorectal Cancer|APC Gene Mutation|TP53 Gene Mutation|PIK3CA Gene Mutation|KRAS Mutation-Related Tumors|MLH1 Gene Mutation
Interventions: OTHER: co-occuring mutation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: Etravirine|DRUG: Ritonavir|DRUG: Darunavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Multivitamin Supplement With Probiotic (Seidivid Ferty4®) on Oocyte Retrieval and Quality
Status: RECRUITING
Conditions: Reproductive Techniques, Assisted
Interventions: DIETARY_SUPPLEMENT: Seidivid Ferty4|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction
Status: COMPLETED
Conditions: Soft Tissue Defect of the Finger
Interventions: PROCEDURE: flap includes a donor nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II
Status: COMPLETED
Conditions: Cerebral Infarction|Atherosclerosis
Interventions: DRUG: clopidogrel|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Direct Current Stimulation on Fatigue Among Multiple Sclerosis Patients.Patients
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: a-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for OUD and Suicidal Ideation in the ED
Status: RECRUITING
Conditions: Opioid Use Disorder|Suicidal Ideation
Interventions: DRUG: Ketamine|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pecto-Intercostal Fascial Plane Block Study
Status: COMPLETED
Conditions: Cardiac Surgery|Opioid Use, Unspecified
Interventions: DRUG: Bupivacaine Injection|DRUG: Liposomal bupivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Single Ascending and Repeated Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TS-142 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TS-142|DRUG: TS-142 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study)
Status: COMPLETED
Conditions: Hypothermia|Heart Arrest
Interventions: PROCEDURE: Comparison of 2 cooling procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prophylactic Ketorolac on CME After Cataract Surgery
Status: COMPLETED
Conditions: Macular Edema, Cystoid
Interventions: DRUG: ketorolac tromethamine 0.5% (Acular®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Safety/Tolerability After Oral Administration of CKD-387 and D635 Under Fed Condition
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CKD-387|DRUG: D635
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency Control of Fluticasone/Formoterol K-haler (Medium Strength) vs ICS/LABA (High Strength) in Asthma Patients
Status: WITHDRAWN
Conditions: Persistent Asthma
Interventions: COMBINATION_PRODUCT: fluticasone/formoterol k-haler (medium strength)|COMBINATION_PRODUCT: Standard of care (ICs/LABA high strength)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Celgosivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermal HIV-1 Immunization During Anti-retroviral Therapy Followed by Repeated Treatment Interruptions
Status: COMPLETED
Conditions: HIV-1
Interventions: BIOLOGICAL: HIV DNA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alfuzosin Treatment in Children and Adolescents With Neurogenic Urinary Bladder Dysfunction
Status: COMPLETED
Conditions: Neurogenic Urinary Bladder
Interventions: DRUG: Alfuzosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of ASP8062 in Healthy Japanese Male and Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ASP8062|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Cystic Fibrosis|Rhinosinusitis
Interventions: DRUG: sodium chloride 6%|DRUG: sodium chloride 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An ObserVatIonal STudy of the Effectiveness of AdaLimumab on Health and Disability Outcomes in New Zealand Patients With Immune-Mediated InflammaTorY Diseases (VITALITY)
Status: COMPLETED
Conditions: Crohn's Disease|Rheumatoid Arthritis|Psoriasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupuncture Versus Laser Acupuncture for Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: laser acupuncture|OTHER: acupuncture|DEVICE: Sham laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy With Herceptin and Taxol for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Taxol|DRUG: Adriamycin|DRUG: Cytoxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study To Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: NKTR-181|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine
Status: COMPLETED
Conditions: Polio|Poliomyelitis
Interventions: BIOLOGICAL: Injectable inactivated types 1, 2 and 3 poliovirus + Live oral Polio|BIOLOGICAL: Injectable inactivated types 1, 2 and 3 poliovirus + Live oral Polio|BIOLOGICAL: Live oral poliovirus type 1, 2 and 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy
Status: UNKNOWN
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Xarlin (Levocetirizine)|DRUG: Cosalin (Petasites hybridus CO2 extract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rebalancing the Serotonergic System in Cocaine Dependence
Status: UNKNOWN
Conditions: Cocaine Dependence
Interventions: DRUG: Lorcaserin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety of Sebryl® and Sebryl Plus® in Seborrheic Dermatitis and Psoriasis of Scalp
Status: COMPLETED
Conditions: Seborrheic Dermatitis|Psoriasis of Scalp
Interventions: OTHER: Allantoin/ Coal Tar/ Clioquinol|OTHER: Allantoin/ Coal Tar/ Clioquinol/ Triclosan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging for the Evaluation of Transthyretin Cardiac Amyloidosis Prevalence of Patients Over 65 Hospitalized in Cardiology Wards (the IMPACT Study)
Status: COMPLETED
Conditions: Transthyretin Cardiac Amyloidosis
Interventions: PROCEDURE: Bony scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous/Subcutaneous FIH Study of REGN1154 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN1154 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine|DEVICE: Vaporizer Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MetfOrmin BenefIts Lower Extremities With Intermittent Claudication
Status: RECRUITING
Conditions: Intermittent Claudication
Interventions: DRUG: Metformin ER|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Reconsolidation of Trauma Memories With Propranolol
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Propranolol|DRUG: Short acting + long acting propranolol + memory reactivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of COVID-19 Infection on the Performance of Adolescent Professional Overhead Athletes
Status: COMPLETED
Conditions: COVID-19|Sport Performance, Professional Overhead Athletes
Interventions: DIAGNOSTIC_TEST: Evaluation of core muscle endurance, hand grip strength, upper extremity functional performance, reaction time, agility performance and 3 minutes step test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Duration of Post-Operative Activity Restriction After Midurethral Sling Procedures
Status: RECRUITING
Conditions: Urinary Stress Incontinence
Interventions: BEHAVIORAL: 3-week post-operative activity restriction|BEHAVIORAL: 6-week post-operative activity restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of PEFLOW on PFM Function Recovery of Postpartum Women
Status: UNKNOWN
Conditions: Pelvic Floor Muscle Weakness|Rehabilitation
Interventions: BEHAVIORAL: Active Comparator: Routine education group|BEHAVIORAL: Experimental: Global training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for Blood Loss Minimization in Endoscopic Pituitary Surgery
Status: WITHDRAWN
Conditions: Pituitary Tumor|Blood Loss|Surgery
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Acupuncture for Dizziness and Vertigo in Emergency Department: a Clinical Control Trial
Status: COMPLETED
Conditions: Dizziness|Vertigo
Interventions: PROCEDURE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics
Status: COMPLETED
Conditions: Laparoscopic Renal Surgery|Laparoscopy|Muscle Relaxation
Interventions: DRUG: Rocuronium|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Expanded Access Study of Alectinib for Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC) After Disease Progression on or Intolerance to Prior ALK Tyrosine Kinase Inhibitor Therapy
Status: NO_LONGER_AVAILABLE
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Alectinib
Study Type: EXPANDED_ACCESS
Clinical trial: Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform
Status: COMPLETED
Conditions: Glioblastoma|Cancer of Brain and Nervous System|Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|PROCEDURE: Stereotactic Radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CAR-BCMA T Cells in Patients With Refractory or Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Refractory or Relapsed Multiple Myeloma
Interventions: GENETIC: CAR-BCMA T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Different Forms of Study Medicine Tafamidis Are Taken Up Into The Blood in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tafamidis 61 mg free acid tablet (Test 1)|DRUG: Tafamidis 70 mg free acid tablet (Test 1)|DRUG: Tafamidis 61 mg free acid capsule (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Safety Study of the Percutaneous Optical Fibre Glucose Sensor (FiberSense)
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DEVICE: FiberSense sensor|DEVICE: Dexcom Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Retrolaminar Block Combined With Erector Spinae Plane Block, and Erector Spinae Plane Block Alone for Post-thoracotomy Pain
Status: RECRUITING
Conditions: Post-thoracotomy Pain Syndrome
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: erector spinae plane block + retrolaminar block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety or Rhythmic Auditory Stimulation (RAS) for Gait and Balance Disorders in Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Rhythmic Auditory Stimulation|BEHAVIORAL: Kinesiology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nicotine Delivery Rate on Reinforcement
Status: COMPLETED
Conditions: Nicotine
Interventions: DRUG: Nicotine saline 0.00mcg/kg/s|DRUG: Nicotine 0.24 mcg/kg/s|DRUG: Nicotine 0.048 mcg/kg/s|DRUG: Nicotine 0.024 mcg/kg/s
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Intimate-partner Violence: Impact Evaluation of Engaging Men Through Accountable Practice in Eastern DRC
Status: COMPLETED
Conditions: Intimate Partner Violence|Domestic Violence|Family Relations
Interventions: BEHAVIORAL: Engaging Men through Accountable Practice|OTHER: Alternative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobilization of Endothelial Progenitor Cells Induced by Atorvastatin in Patients With Stable Coronary Artery Disease Treated With Anti-CD 34 Antibodies Coated Stents
Status: TERMINATED
Conditions: Stable Coronary Artery Disease
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: sodium phenylbutyrate|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative|Anesthesia
Interventions: DRUG: Bupivacaine|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Prediabetic State
Interventions: DRUG: Pravastatin|DRUG: Placebo (for Pravastatin)|BEHAVIORAL: Nutritional education only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa Bacteraemia
Status: RECRUITING
Conditions: Bloodstream Infection
Interventions: DRUG: Short-treatment of any active antibiotic regimen|DRUG: Long-treatment of any active antibiotic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Romidepsin (Depsipeptide) in Combination With Gemcitabine in Patients With Pancreatic and Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Romidepsin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children
Status: UNKNOWN
Conditions: Nocturnal Enuresis
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Myopia Macular Hole and Retinal Detachment Treated With Double ILM Flaps
Status: COMPLETED
Conditions: High Myopia|Macular Holes|Retinal Detachment
Interventions: PROCEDURE: Inverted and free ILM insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Continued Safety and Performance of the Foot and Ankle Products
Status: RECRUITING
Conditions: Hyperpronated Foot|Reconstruction Surgeries of the Foot|Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle|Fixation of Small Bone Fragments of the Foot/Ankle|Lisfranc Arthrodesis|Mono or Bi-cortical Osteotomies in the Forefoot|First Metatarsophalangeal Arthrodesis|Akin Osteotomy|Midfoot and Hindfoot Arthrodeses or Osteotomies|Fixation of Osteotomies for Hallux Valgus Treatment (Scarf and Chevron)|Arthrodesis of the Metatarsocuneiform Joint to Reposition and Stabilize Metatarsus Primus Varus|Osteotomy Fixation of Hallux Valgus Repair (Such as Scarf and Chevron Etc.)
Interventions: DEVICE: Products listed in Group/Cohort Description
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Preconditioning Over Time To Empower Cerebral Tissue
Status: TERMINATED
Conditions: Ischemic Stroke|Cerebral Small Vessel Disease|Cognitive Decline
Interventions: DEVICE: Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 HAE Prophylaxis Study With Recombinant Human C1 Inhibitor
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: Recombinant human C1 inhibitor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Prebiotics on Intestinal Gas Production, Microbiota and Digestive Symptoms
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Bimuno Galacto-oligo-saccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE