pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients.
Status: COMPLETED
Conditions: Coronary Artery Disease|Edema
Interventions: DRUG: 7.2% NaCl plus 6% hydroxyethyl starch 200/0.5|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Fenofibrate|DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium|Agitation, Emergence
Interventions: DEVICE: Bridge Therapy|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection
Status: RECRUITING
Conditions: Intestinal Disease
Interventions: DRUG: Neostigmine Injectable Solution|DRUG: Sugammadex injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of ADHD
Status: ENROLLING_BY_INVITATION
Conditions: Infant Behavior|Infant Development|Self-Control|Self-Regulation, Emotion
Interventions: BEHAVIORAL: Early Self-Regulation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial of Hinex Jelly on the Changes in Muscle Quality and Quantity
Status: RECRUITING
Conditions: Nutrition, Healthy|Muscle Weakness|Elderly
Interventions: DIETARY_SUPPLEMENT: Hinex Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: How Can a Driving Virtual Reality Tool Improve Quality of Life and Social Autonomy in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Virtual reality driving stimulation program|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gastric Delay in Migraine Patients (3207-003)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: MK3207|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of FETO for Severe Congenital Diaphragmatic Hernia
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the delivery Microcatheter (BALTACCI-BDPE100)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe
Status: COMPLETED
Conditions: Carcinoma|Renal Cell|Non Clear Cell Renal Carcinoma|Papillary Cell Renal Carcinoma|Adenocarcinoma
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Tetrabenazine MR in Pediatric Subjects With Tourette's Syndrome
Status: WITHDRAWN
Conditions: Tourette's Syndrome
Interventions: DRUG: Tetrabenazine MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Fenofibrate on Retinal Thickness and Macular Volume
Status: COMPLETED
Conditions: Diabetic Retinopathy|Dyslipidemias|Diabetes Mellitus
Interventions: DRUG: Fenofibrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Early Echographic Asystole as a Predictive Factor of Absence of Spontaneous Circulatory Activity Recovery (SCAR) in Prehospital Cardio Respiratory Arrests (CRA)
Status: COMPLETED
Conditions: Prehospital Cardio-Respiratory Arrests|Spontaneous Circulatory Activity Recovery
Interventions: OTHER: Non applicable - Non interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Application of Nutrition Support Package Before Hepatectomy
Status: UNKNOWN
Conditions: Liver Neoplasms|Nutrition Therapy|Hepatectomy
Interventions: DIETARY_SUPPLEMENT: 300 calories or 500 calories nutrient rich in branched chain amino acids and dietary fiber|BEHAVIORAL: Dietary mission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Triple -Negative Breast Cancer|Estrogen Receptor Negative|HER2/Neu Negative|Anatomic Stage IV Breast Cancer AJCC|Progesterone Receptor Negative
Interventions: PROCEDURE: Biopsy|PROCEDURE: Chemokine Modulation Therapy|DRUG: Celecoxib|BIOLOGICAL: Recombinant Interferon Alfa-2b|DRUG: Rintatolimod|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of KIR-Ligand Mismatched Haplo-Identical Natural Killer Cells Transfused Before Autologous Stem Cell Transplant
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Melphalan|DRUG: Fludarabine|DRUG: Bortezomide|PROCEDURE: Leukapheresis|DRUG: Interleukin|PROCEDURE: Infusion #1|PROCEDURE: Leukapheresis #2|PROCEDURE: Infusion #2|PROCEDURE: Auto Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize)
Status: RECRUITING
Conditions: Locally Advanced, Squamous Cell Carcinoma of the Vulva
Interventions: DRUG: Paclitaxel and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Response and Recurrence Rates Following Percutaneous Microwave Coagulation Therapy Versus Percutaneous Radiofrequency Ablation
Status: COMPLETED
Conditions: Thermoablation|Chronic Liver Disease|Hepatocellular Carcinoma
Interventions: OTHER: Percutaneous Radiofrequency Ablation|OTHER: Percutaneous Microwave Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing the Efficacy of Two Neurofeedback Protocols for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DEVICE: EEG Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction
Status: WITHDRAWN
Conditions: Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma|Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma|Metastatic Malignant Solid Neoplasm|Stage III Hepatocellular Carcinoma AJCC v7|Stage IIIA Hepatocellular Carcinoma AJCC v7|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v7|Stage IVA Hepatocellular Carcinoma AJCC v7|Stage IVB Hepatocellular Carcinoma AJCC v7|Unresectable Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults
Status: COMPLETED
Conditions: Aging|Sedentary Behavior
Interventions: DIETARY_SUPPLEMENT: Cocoa flavanols|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Testing P2Y12 Platelet Inhibitors Generics Beyond Bioequivalence
Status: COMPLETED
Conditions: Cardiovascular Diseases|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor 90mg (Brilique)|DRUG: Ticagrelor 90mg (Ticaloguard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 12-week Supplementation With Olive Leaf Extract in Postmenopausal Women (FEMMED)
Status: COMPLETED
Conditions: Post-Menopausal Women
Interventions: DIETARY_SUPPLEMENT: Olive Leaf Extract|DIETARY_SUPPLEMENT: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Plantar Stimulation on Hypotension, Treatment Efficacy and Quality of Life With Adults on Hemodialysis
Status: WITHDRAWN
Conditions: Hypotension
Interventions: DEVICE: Calf Muscle Pump Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Aerobic Exercise on Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio and Lymphocyte-Monocyte Ratio in Burn Patients: A Randomized Controlled Study
Status: RECRUITING
Conditions: Burns|Physiotherapy|Aerobic Exercises
Interventions: OTHER: Control Group|OTHER: Aerobic Exercises group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Eggs and Egg Products on Macular Pigment
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: not enriched egg|DIETARY_SUPPLEMENT: lutein|DIETARY_SUPPLEMENT: zeaxanthin|DIETARY_SUPPLEMENT: egg product from enriched eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Fentanyl Versus Pethidine During Propofol-based Sedated Colonoscopy: Prospective Randomized Study
Status: UNKNOWN
Conditions: Health Check up Colonoscopy
Interventions: DRUG: fentanyl doses|DRUG: pethidine dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Safety and Pharmacokinetic Study of TAK-228 in Combination With TAK-117 in Adult Participants With Advanced Nonhematologic Malignancies
Status: COMPLETED
Conditions: Advanced Nonhematologic Malignancies
Interventions: DRUG: TAK-228|DRUG: TAK-117
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Docetaxel, and Cetuximab in Patients With Unresectable Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effectiveness of Vibroacoustic Therapy for Respiratory Failure Caused by COVID 19
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome|Hypoxemia
Interventions: DEVICE: VibroLUNG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Post Conditioning + Primary PCI|PROCEDURE: Standard Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Dysplasia|Lip and Oral Cavity Carcinoma|Oral Disorder|Premalignant Lesion
Interventions: PROCEDURE: Biopsy|PROCEDURE: Fluorescence Imaging|PROCEDURE: High-Resolution Microendoscopy|DRUG: Proflavine Hemisulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rate of Bronchopulmonary Dysplasia in Preterms Neonates: a Trial Comparing SMOFlipid and Medialipide
Status: WITHDRAWN
Conditions: Preterm Neonates
Interventions: DIETARY_SUPPLEMENT: SMOFlipid®|DIETARY_SUPPLEMENT: Medialipide®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Hesperidin and Flaxseed on Biochemical Factors and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: hesperidin and flaxseed|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diffusion Weighted Imaging -MRI in Patients With Resectable Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Liver Metastases|Colorectal Cancer
Interventions: OTHER: Experimental: imaging arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving The Nutritional Status Of The Malnourished Chronic Hemodialysis Patients In The State Of Tennessee
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: Nepro nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short- and Long-term Outcomes of Robotic vs Laparoscopic Right Colon Cancer: a 10-year Single-center Retrospective Study
Status: COMPLETED
Conditions: Robotic|Laparoscopic|Colon Cancer|Long-term Outcomes|Short-term Outcomes
Interventions: DEVICE: Da Vinci Robot Surgical System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1
Status: COMPLETED
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: domatinostat in combination with avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Feeding During Therapeutic Hypothermia Safe and Can Improve Outcomes in Infants With Hypoxic-ischaemic Encephalopathy
Status: RECRUITING
Conditions: Newborn Asphyxia
Interventions: OTHER: enteral feeding with mother milk or human donor breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of an Immune Modulator Dimethyl Fumarate on Acute Ischemic Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide in Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: Inhaled nitric oxide (NO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study Comparing CD07805/47 Gel 0.5% to Azelaic Acid Gel 15% in Subjects With Erythema of Rosacea
Status: COMPLETED
Conditions: Erythema|Rosacea
Interventions: DRUG: CD07805/47 gel 0.5%/CD07805/47 Vehicle|DRUG: azelaic acid gel 15%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab (Campath-1H) Monoclonal Antibody in Patients With Relapsed and Resistant Classical Hodgkin's Disease
Status: WITHDRAWN
Conditions: Hodgkin's Disease|Lymphoma
Interventions: DRUG: Alemtuzumab (Campath-1H)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Status: COMPLETED
Conditions: Pain Following Thoracotomy Surgery
Interventions: DRUG: Epidural|DRUG: Intercostal Bupivicaine (Exparel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lessons in Affect Regulation to Keep Stress and Pain UndeR Control (LARKSPUR R34)
Status: COMPLETED
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: LARKSPUR; Online Positive Emotions Skills for Individuals with Chronic Musculoskeletal Pain|BEHAVIORAL: Emotion Reporting Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin
Status: COMPLETED
Conditions: Drug Interactions|Pharmacokinetics
Interventions: DRUG: Daptomycin|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Integration of Palliative and Supportive Care in Cellular Therapy
Status: RECRUITING
Conditions: Leukemia|Lymphoma|Multiple Myeloma|Blood Cancer|Stem Cell Transplant Complications|Chimeric Antigen Receptor T-cell Therapy
Interventions: OTHER: Early palliative and supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-surgical Periodontal Treatment With Adjunctive Use of Lactoferrin Contained in Toothpaste and Mouthwash
Status: ENROLLING_BY_INVITATION
Conditions: Periodontal Diseases
Interventions: OTHER: Emoform Glic Toothpaste|OTHER: Emoform Glic Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy in Treating Patients With Lung Cancer That Has Spread to the Other Lung or Parts of the Body
Status: WITHDRAWN
Conditions: Advanced Malignant Mesothelioma|Extensive Stage Small Cell Lung Cancer|Lung Metastases|Recurrent Malignant Mesothelioma|Recurrent Non-small Cell Lung Cancer|Recurrent Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: PROCEDURE: cryotherapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ginseng in Type 2 Diabetes
Status: COMPLETED
Conditions: Type II Diabetes Control
Interventions: DIETARY_SUPPLEMENT: CNT 2000 American ginseng extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Modafinil's Effects on Cognition in Remitted MDD
Status: TERMINATED
Conditions: Major Depressive Disorder|Cognitive Impairment
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Voriconazole in Obese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Voriconazole low dose|DRUG: Voriconazole high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Native Whey or Milk Supplementation on Adaptations to 12 Weeks of Strength Training in Young and Elderly
Status: COMPLETED
Conditions: Healthy|Young|Elderly
Interventions: DIETARY_SUPPLEMENT: Native whey|DIETARY_SUPPLEMENT: Milk|OTHER: Strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture Reduces Relapse in Patients With Crohn's Disease: a Superiority Trial
Status: RECRUITING
Conditions: Crohn's Disease Relapse|Inflammatory Bowel Diseases
Interventions: OTHER: "Harmonizing Shaoyang, nourishing spleen and kidney with warmth" Acupuncture Group|OTHER: "Nourishing spleen and kidney with warmth" Acupuncture Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relevance of the Urine Bacterial Culture Performed Before Double J Ablation for Post-operative Urinary Tract Infection Prevention
Status: RECRUITING
Conditions: Urinary Infection
Interventions: PROCEDURE: CBEU|PROCEDURE: No CBEU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery
Status: COMPLETED
Conditions: Intrauterine Growth Retardation
Interventions: PROCEDURE: selective laser photocoagulation of communicating vessels|DEVICE: Expected Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy
Status: RECRUITING
Conditions: Stage III Lung Cancer AJCC v8|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Cancer AJCC v8|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Cancer AJCC v8|Stage IIIB Lung Non-Small Cell Cancer AJCC v7|Stage IIIC Lung Cancer AJCC v8
Interventions: DRUG: Carboplatin|BIOLOGICAL: Durvalumab|DRUG: Gemcitabine|PROCEDURE: Local Consolidation Therapy|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|DRUG: Pemetrexed|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alexithymia Intervention for Suicide
Status: RECRUITING
Conditions: Suicide|Schizophrenia|Bipolar Disorder|Post Traumatic Stress Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Affective Awareness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Candesartan Effect in Second Stage Arterial Hypertension
Status: COMPLETED
Conditions: Stage II Hypertension
Interventions: DRUG: Candesartan Cilexetil|DRUG: Hydrochlorothiazide|DRUG: Candesartan Cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK2461 Phase I/II Study in Patients With Advanced Solid Tumors (MK-2461-002 AM1)(COMPLETED)
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: MK2461
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial23 - A Method Study on Cervical Screening in Women Offered HPV-vaccination as Girls
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia (CIN)
Interventions: DEVICE: Cobas HPV-DNA test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: iSIPsmarter: An RCT to Evaluate the Efficacy of a Technology-based Behavioral Intervention to Reduce Sugary Beverages Among Rural Appalachian Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Diet Habit|Sugar-Sweetened Beverages
Interventions: BEHAVIORAL: iSIPsmarter|BEHAVIORAL: Patient Education (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Thrombocytopenia
Interventions: DRUG: temozolomide|GENETIC: comparative genomic hybridization|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|RADIATION: radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Ivermectin in COVID-19
Status: COMPLETED
Conditions: Safety|SARS-CoV2 Infection|Ivermectin Poisoning|Effect of Drug
Interventions: DRUG: Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Cleansers on the Skin
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: OTHER: CeraVe® Eczema Soothing Body Wash|OTHER: Cetaphil® RestoraDerm® Eczema Calming Body Wash|OTHER: Dove® Sensitive Skin Body Wash|OTHER: Eucerin® Skin Calming Body Wash|OTHER: Aveeno® Skin Relief Body Wash|OTHER: MooGoo® Milk Wash|OTHER: Free & Clear Liquid Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Educational Efficacy Assessment of a Serious Game to Teach Insulin Therapy to Primary Care Physicians
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Knowledge, Attitudes, Practice
Interventions: OTHER: Game|OTHER: Traditional CME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Occupational Therapy Programme of Patients With Dementia Performing Activities of Daily Living
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Stimulation of Activities Daily Living|OTHER: Conventional ADLOccupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Two Tablets of Ivermectin Tablets (3 mg Ivermectin) Versus Two Tablets of Stromectol ® Tablets (3 mg Ivermectin), in Healthy Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Anthelmintic Agent
Interventions: DRUG: Ivermectin tablets (3 mg Ivermectin)|DRUG: Stromectol ® tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 mcg BID
Status: COMPLETED
Conditions: Asthma|Candidiasis, Oral|Voice Disorders
Interventions: DRUG: fluticasone/salmeterol DISKUS 250/50
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|Breast Cancer, Male|Invasive Breast Cancer|HER2-positive Breast Cancer|HER2 Positive Breast Carcinoma|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: BIOLOGICAL: Dendritic Cell Vaccine (DC1)|DRUG: Neoadjuvant Chemotherapy|PROCEDURE: Curative Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-MhGAP Intervention Guide in Low- and Middle-income Countries: Proof-of-concept for Impact and Acceptability
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: paper-based version of mental health Gap Action Program-Intervention Guide|OTHER: digital version of the mental health Gap Action Program-Intervention Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stress & Social Cognition in BPD (Part 2)
Status: RECRUITING
Conditions: Borderline Personality Disorder
Interventions: DRUG: Fludrocortisone|DRUG: Placebo|BEHAVIORAL: Trier Social Stress Test (TSST)|BEHAVIORAL: Placebo Trier Social Stress Test (P-TSST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influenza A (H7N9) Vaccine Delivered Intradermally by High-density Microarray Patch (HD-MAP)
Status: RECRUITING
Conditions: H7N9 Influenza
Interventions: BIOLOGICAL: Unadjuvanted Influenza A (H7N9) Monovalent Vaccine Injection|COMBINATION_PRODUCT: Unadjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (low dose HA)|COMBINATION_PRODUCT: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (high dose HA)|BIOLOGICAL: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Injection|COMBINATION_PRODUCT: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (low dose HA, low dose adjuvant)|COMBINATION_PRODUCT: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (low dose HA, high dose adjuvant)|COMBINATION_PRODUCT: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (high dose HA, low dose adjuvant)|COMBINATION_PRODUCT: Adjuvanted Influenza A (H7N9) Monovalent Vaccine Microarray Patch Delivery System (high dose HA, high dose adjuvant)|DEVICE: Microarray Patch Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease II
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Olodaterol (BI 1744)|DRUG: Olodaterol (BI 1744)|DRUG: Formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack
Status: WITHDRAWN
Conditions: Transient Ischemic Attack|Stroke|Aspirin|Clopidogrel
Interventions: DRUG: aspirin versus clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-438 in Healthy Male Participants
Status: COMPLETED
Conditions: Dose Finding Study
Interventions: DRUG: TAK-438|DRUG: TAK-438 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Effectiveness of a Communication Facilitator : A Randomized Trial
Status: UNKNOWN
Conditions: Intensive Care Unit|Life Stress|Family Members|Facilitation, Social
Interventions: BEHAVIORAL: Facilitator-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Urothelial Carcinoma
Interventions: DRUG: 18F-fluciclovine|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recovery From Anesthesia After Robotic Assisted Radical Cystectomy
Status: UNKNOWN
Conditions: Anesthesiology Management
Interventions: DRUG: Sugammadex Injectable Product|DRUG: Neostigmine, Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder|Stress Reaction|Social Stress|Craving|Relapse|Addiction, Alcohol|Risk Behavior
Interventions: BEHAVIORAL: Trier Social Stress Test|BEHAVIORAL: Barlab Cue-Exposure|BEHAVIORAL: Functional magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion
Status: COMPLETED
Conditions: Spinal Fusion
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health
Status: NOT_YET_RECRUITING
Conditions: Chagas Disease
Interventions: DRUG: Nifurtimox (BAYA2502)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcatheter Leak Closure With Detachable Coils Following Incomplete Left Atrial Appendage Closure Procedures
Status: UNKNOWN
Conditions: Left Atrial Appendage Incomplete Closure
Interventions: DEVICE: Interlock-35 Fibered IDC Occlusion System|DEVICE: Concerto Helix Detachable Coil System|DEVICE: Azur Peripheral Coil System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: Bevacizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Laser Therapy for Treatment of Vaginal Dryness in Survivors of Breast Cancer, The Revitalize Trial
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Vaginal Atrophy
Interventions: DEVICE: Laser Therapy|DEVICE: Sham Intervention|OTHER: Questionnaire Administration|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Status: COMPLETED
Conditions: Cognitive Disorders|Delirium|Acute Kidney Injury
Interventions: DRUG: Ketamine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prediction of the Collapse of Necrotic Femoral Head Using Computed Tomography Scan and X-ray Before Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthropathy
Interventions: RADIATION: X-ray|RADIATION: CT|OTHER: specimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort
Status: RECRUITING
Conditions: Recurrent Adult Soft Tissue Sarcoma
Interventions: PROCEDURE: Conventional Surgery|RADIATION: Hypofractionated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Sublingual Spray and Fentanyl Citrate Intravenous (IV) in Opioid Naive Subjects
Status: COMPLETED
Conditions: Pharmacokinetics and Pharmacodynamics
Interventions: DRUG: Fentanyl|DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding Adaptive Immune Response After COVID-19 Vaccination Boosters to Improve Vaccination Strategies in Vulnerable Groups.
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: Analisys of cellular response and humoral response to SARS-CoV-2 vaccine booster doses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Free Combinations of Tiotropium Inhalation Powder Capsule + Salmeterol Metered Dose Inhaler, Tiotropium Inhalation Powder Capsule and Salmeterol Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Salmeterol|DRUG: Placebo-MDI|DRUG: Placebo HandiHaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: BEAM COPD: Breathing, Education, Awareness and Movement in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Tai chi|BEHAVIORAL: Mind-body breathing|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Thromboprophylaxis in Oesophageal Cancer Patients
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Thrombosis|Thromboembolism
Interventions: DRUG: Fragmin 5000 UNT in 0.2 ML Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Control-IQ Technology for High Insulin Users With Type 1 Diabetes (Higher-IQ)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: t:slim X2 insulin pump with Control-IQ technology 1.5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
Status: UNKNOWN
Conditions: Thoracic Aortic Aneurysm|Respiratory Insufficiency
Interventions: DRUG: Immunonutrition ( Impact)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Arthrocentesis With and Without PRP Injection in Patients With Disc Displacement With Reduction.
Status: COMPLETED
Conditions: TMJ Disc Disorder
Interventions: PROCEDURE: arthrocentesis without PRP|PROCEDURE: arthrocentesis with PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CASAD for Severe Diarrhea in the Emergency Department
Status: TERMINATED
Conditions: Cancer|Diarrhea
Interventions: DRUG: Calcium Alumina-Silicate (CASAD)|OTHER: Placebo|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Ventilation Patterns on Lung Injury
Status: UNKNOWN
Conditions: Lung Injury
Interventions: PROCEDURE: pressure-controlled ventilation-volume guaranteed|PROCEDURE: volume controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Test Safety, Tolerability and Blood Levels of GSK971086 After 1 Dose & 7 Days of Dosing in Healthy Adult Males
Status: COMPLETED
Conditions: Healthy Subjects|Androgen Deficiency
Interventions: DRUG: placebo|DRUG: GSK971086
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: PRO-148|DRUG: Systane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Sensorimotor Prosthesis for the Upper Limb
Status: RECRUITING
Conditions: Prosthesis Durability|Prosthesis User|Amputation|Amputation; Traumatic, Hand
Interventions: DEVICE: PROLIMB Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Multiple Doses of HM15136 in Obese or Overweight Subjects With Comorbidities
Status: COMPLETED
Conditions: Obese With Comorbidities|Overweight With Comorbidities|Type2 Diabetes
Interventions: DRUG: HM15136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-705a Multicenter Study in Adults Subjects With Uncomplicated Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Placebo|DRUG: Favipiravir|DRUG: Favipiravir|DRUG: Favipiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: FF-10501-01|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Imaging Biomarkers Associated With Plasma ad Cellular Determinants of Cardiovascular Disease at the Time of COVID 19
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: sample blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment
Status: RECRUITING
Conditions: Blindness|Blindness, Acquired|Low Vision|Blindness, Complete
Interventions: BEHAVIORAL: Cognitive-Kinesthetic Navigational Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LM-108 as a Single Agent or in Combination With Anti-PD-1 Antibody in Subjects With Advanced Solid Tumours
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: LM-108|DRUG: An Anti-PD-1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depression in the Elderly and Cerebral Amyloid Plaques: Characterization by [18F] AV-45 Affectives Symptoms and Amyloïd Plaques (ASAP)
Status: COMPLETED
Conditions: Elderly|Major Depression
Interventions: DRUG: 18FAV45
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Application of Latanoprost in Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TLIP Block for Postoperative Analgesia of Lumbar Spinal Fusion
Status: COMPLETED
Conditions: Lumbar Spinal Fusion
Interventions: PROCEDURE: TLIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Remotivation Process for Improving Adherence to Lymphedema Treatment Programs in Patients With Breast Cancer-Related Lymphedema
Status: COMPLETED
Conditions: Breast Carcinoma|Lymphedema
Interventions: OTHER: Best Practice|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Motivational Interviewing|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE