pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Vorinostat (MK-0683) With Follicular Lymphoma (FL), Other Indolent B-cell Non-Hodgkin's Lymphoma (B-NHL), or Mantle Cell Lymphoma (MCL) Participants (MK-0683-103)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Patient Decision Support System for Patients With Type 2 Diabetes (DiaPaDeSS)
Status: NOT_YET_RECRUITING
Conditions: Mobile Health|Type 2 Diabetes|Patient Activation|Self-Management|Decision Support System|Nursing|Randomized Controlled Trial
Interventions: BEHAVIORAL: DiaPaDeSS|BEHAVIORAL: DiaPaDeSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CKD-330 Drug-Drug Interaction Study (Amlodipine)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine 10mg|DRUG: Amlodipine 10mg/Candesartan 32mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children
Status: TERMINATED
Conditions: Malaria
Interventions: DRUG: Sulfadoxine Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Phase 2, Double Blind, Placebo-controlled, Randomized Study is to Assess the Safety and Efficacy of Miricorilant in Obese Adult With Schizophrenia or Bipolar Disorder Treated With Antipsychotic Medications.
Status: COMPLETED
Conditions: Antipsychotic-induced Weight Gain (AIWG)
Interventions: DRUG: Miricorilant|DRUG: Miricorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma
Status: COMPLETED
Conditions: Esophageal Cancer|Adenocarcinoma, Esophageal|Adenocarcinoma, Gastroesophageal Junction
Interventions: DRUG: (Epirubicin Cisplatin 5-Fluorouracil / Xeloda) OR 5-Fluorouracil Leucovorin Oxaliplatin Docetaxel|OTHER: Carboplatin paclitaxel plus concurrent radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imapct of bioMarkers on Pharmacodynamics and Bleeding Risk of Direct Oral AntiCoagulants and Ticagrelor Study II
Status: NOT_YET_RECRUITING
Conditions: Novel Oral Anticoagulants|NOACs|Rivaroxaban|Apixaban|Edoxaban|Dabigatran|Ticagrelor|Pharmacodynamics|Pharmacogenomics|RNA Profile|Bleeding|Biomarker
Interventions: GENETIC: Detection of genotype and RNA profile in platelet and white blood cell|OTHER: Indicators test related to coagulation function|OTHER: Indicators test related to platelet function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Efficacy and Safety of AryoGen Pharmed Biosimilar Trastuzumab (AryoTrust) Versus Herceptin® in Breast Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: DRUG: Trastuzumab plus docetaxel (for four 21-day cycles) after four 14-day cycles of Doxorubicin plus cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Autologous Renal Autologous Cell Therapy (REACT) in Patients With Diabetic Chronic Kidney Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbial Transplantation for Rheumatoid Arthritis Trial
Status: RECRUITING
Conditions: Arthritis|Arthritis, Rheumatoid|Fecal Microbiota Transplantation
Interventions: DRUG: Fecal Microbial transplant|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study
Status: ENROLLING_BY_INVITATION
Conditions: Type 2 Diabetes|Diabetes Type 2|Diabetic Nephropathies|Nephropathy|Obesity|Adolescent Obesity|Diabetic Kidney Disease
Interventions: DRUG: Aminohippurate Sodium Inj 20%|DRUG: Iohexol Inj 300 MG/ML|DRUG: Dextran 40|PROCEDURE: Renal Biopsy|RADIATION: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Challenge Study of an ETEC Vaccine
Status: COMPLETED
Conditions: Enteritis; Escherichia Coli, Enterotoxigenic
Interventions: BIOLOGICAL: LTR192G with dscCfaE|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Gel and Vascular ND in Mild to Moderate Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Azelaic acid|DEVICE: Nd:Yag laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD7442 - a Potential Combination Therapy for the Prevention and Treatment of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: COMBINATION_PRODUCT: AZD7442|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly
Status: NOT_YET_RECRUITING
Conditions: Primary Care|Health Plan Implementation|Benzodiazepine Dependence|Elderly|Anxiety|Deprescribing
Interventions: BEHAVIORAL: GP - pharmacist collaboration and pharmacist motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial to Assess Campath-1H and Tacrolimus Followed by Immunosuppression Withdrawal in Liver Transplantation
Status: COMPLETED
Conditions: Transplantation, Liver
Interventions: DRUG: Campath-1H and Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: Injection of 20% dextrose/ 0.2% lidocaine|OTHER: Injection of 1 ml of 0.8 SW/0.2% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress
Status: RECRUITING
Conditions: Stress Physiology
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Prebiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: High-dose Cyclophosphamide for Moderate to Severe Refractory Chronic Inflammatory Demyelinating Polyneuropathy
Status: WITHDRAWN
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Doxorubicin and Paclitaxel (GAT) as Neoadjuvant Treatment of Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Adriamycine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Herombopag in Tumors-associated Thrombocytopenia
Status: UNKNOWN
Conditions: Tumor Therapy-related Thrombocytopenia
Interventions: DRUG: TPO-RA (Herombopag)|DRUG: TPO-RA (Herombopag) and rhTPO(Recombinant human thrombopoietin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Virtual Reality Fully Immersive Based Exercise Game on Reducing Fear of Movement in People With CLBP
Status: UNKNOWN
Conditions: CLBP - Chronic Low Back Pain
Interventions: DEVICE: (kurki-application),VR glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor 60mg|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Measurement Using Microneedle Patches
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Microneedle patch|DEVICE: Intravenous (IV) catheter|DEVICE: Lancet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Determinants of the Level of Anti-SARS-CoV-2 IgG ANTibodiEs After Vaccination Study in Patients After Organ Transplantation
Status: UNKNOWN
Conditions: SARS-CoV2 Infection|SARS-CoV2 Antibodies
Interventions: DIAGNOSTIC_TEST: assessment of the anti-SARS-CoV-2 IgG antibody titer in 3-dose schedule|DIAGNOSTIC_TEST: assessment of the anti-SARS-CoV-2 IgG antibody titer in 2-dose schedule
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-Dose And Multiple-Dose Safety And Tolerability Study Of PF-04856883 In Type 2 Diabetic Adult Females
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders|Metabolic Diseases|Endocrine System Diseases
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: Placebo|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: Placebo|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Cholangiocarcinoma|Gallbladder Cancer|Gallbladder Carcinoma|Intrahepatic Cholangiocarcinoma|Extrahepatic Cholangiocarcinoma|Bile Duct Cancer|Gall Bladder Cancer|Gall Bladder Carcinoma
Interventions: DRUG: LSTA1|DRUG: Durvalumab|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: FOLFOX regimen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare the Safety and Pharmacokinetic Characteristics of Combination of Rosuvastatin and CS-866 and DWJ1276
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cresto|DRUG: Olmetec|DRUG: DWJ1276
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lymphocytes, Activated
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3Ps for Prevention Study (Perception, Partners, Pills)
Status: UNKNOWN
Conditions: Adherence
Interventions: BEHAVIORAL: Incentivised - Conditional Cash Transfer|DRUG: Truvada 200Mg-300Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome
Status: RECRUITING
Conditions: Poly Cystic Ovary Syndrome
Interventions: DRUG: Metformin Hydrochloride tablet|DRUG: Vildagliptin 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term OL Study of [S,S]-RBX in Patients With Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: [S,S]-reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study of the Effectiveness of Carisbamate in the Treatment of Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor, Movement Disorders
Interventions: DRUG: Carisbamate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polypectomy With Hot vs Cold Snare in Small Colonic Lesions
Status: COMPLETED
Conditions: Polyp of Colon|Gastrointestinal Bleeding|Colonic Adenoma
Interventions: PROCEDURE: hot snare|PROCEDURE: cold snare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis Exclusion of Recurrent Deep Vein Thrombosis of the Lower Limbs
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DIAGNOSTIC_TEST: Colour doppler ultrasound with or without D-dimer test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety Study of the Auditory Brainstem Implant for Pediatric Profoundly Deaf Patients
Status: UNKNOWN
Conditions: Profound Bilateral Deafness Due to|Bilateral Cochlear Aplasia|Bilateral Cochlear Nerve Deficiency|Bilateral Cochlear Ossification Secondary to Meningitis
Interventions: DEVICE: Auditory Brainstem Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Cell Therapy After Stroke
Status: WITHDRAWN
Conditions: Stroke
Interventions: BIOLOGICAL: autologous bone marrow mononuclear cell transfusion|BIOLOGICAL: marrow stromal cells|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 7 NUTS Study. Diet Modification and Male Fertility.
Status: UNKNOWN
Conditions: Male Subfertility|Oligospermia|Asthenospermia|Teratospermia
Interventions: DIETARY_SUPPLEMENT: 7 nuts a day|OTHER: Diet modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing HIV/STI in Urban Adolescents Via an mHealth Primary Care Intervention
Status: COMPLETED
Conditions: HIV/AIDS and Infections|Drug Abuse|Adolescent Behavior|Drug Usage
Interventions: BEHAVIORAL: S4E|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bilirubin Binding Capacity to Assess Bilirubin Load in Preterm Infants
Status: COMPLETED
Conditions: Bilirubin-induced Neurologic Dysfunction|Hyperbilirubinemia|Kernicterus|Infant, Premature|Infant, Low Birth Weight
Interventions: DIAGNOSTIC_TEST: Bilirubin Binding Capacity|DIAGNOSTIC_TEST: End-tidal Carbon Monoxide|DIAGNOSTIC_TEST: Carboxyhemoglobin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In-vivo Efficacy Study of Patient Preoperative Preps
Status: TERMINATED
Conditions: Skin Flora Bacterial Reduction Post-product Application
Interventions: DRUG: 3M CHG/IPA Prep Colorless|DRUG: 3M CHG/IPA Prep Tint|DRUG: ChloraPrep|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Combination immunotherapy with Ipilimumab and Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sunitinib in Combination With Bevacizumab and Paclitaxel in Previously Untreated Patients With Metastatic Breast Cancer (SABRE-B)
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: bevacizumab|DRUG: sunitinib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Study of a Plasmid DNA Prime and MVA Boost Vaccine in HIV-1 Infected Adults on ART
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: JS7 plasmid DNA and MVA62B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Interaction Between BCG And MenC Immunisation: BAM
Status: COMPLETED
Conditions: BCG Infection|Reaction - Vaccine|Immune Response
Interventions: BIOLOGICAL: BCG, NeisVac-C®, Pediacel®, Infanrix™, Prevenar-13®, Menitorix®, Priorix®, Rotarix®|BIOLOGICAL: BCG, NeisVac-C®, Pediacel®, Infanrix™, Prevenar-13®, Menitorix®, Priorix®, Rotarix®|BIOLOGICAL: NeisVac-C®, Pediacel®, Infanrix™, Prevenar-13®, Menitorix®, Priorix®, Rotarix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Assess the Safety of Reducing the Time of Bed Rest After Cardiac Catheterization
Status: COMPLETED
Conditions: Coronary Artery Disease With Myocardial Infarction
Interventions: OTHER: Rest three hours|OTHER: Rest five hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate First-line Ipilimumab + Nivolumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Nivolumab + ipilimumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: Icatibant|DRUG: Tranexamic Acid|DRUG: Oral Placebo|DRUG: S.C. Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: pDNA Intralesional Cancer Vaccine for Cutaneous Melanoma
Status: COMPLETED
Conditions: Cutaneous Melanoma, Stage III|Cutaneous Melanoma, Stage IV
Interventions: BIOLOGICAL: IFx-Hu2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascial Closure Techniques Post-Operative Pain Laparoscopy
Status: COMPLETED
Conditions: Post-operative Pain|Fascial Closure
Interventions: PROCEDURE: Conventional technique|PROCEDURE: Berci technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use|Substance Abuse|Suicide
Interventions: BEHAVIORAL: Thiwáhe Gluwáš'akapi|BEHAVIORAL: Woyute Waśte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Trial to Determine the Efficacy of VSL#3 for Reducing Colonization by VRE
Status: COMPLETED
Conditions: Anti-biotic Resistance
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: sugar pill (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.
Status: RECRUITING
Conditions: Analgesia|Lidocaine|Intensive Care Unit
Interventions: DRUG: lidocaine treatment|DRUG: serratus plane block treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: walk2Wellness: Long-term Effects of Walkasins® Wearable Sensory Prosthesis
Status: COMPLETED
Conditions: Sensory Peripheral Neuropathy|Balance; Distorted|Sensation Disorders
Interventions: DEVICE: Walkasins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection
Status: COMPLETED
Conditions: Calcifying Tendinitis of Shoulder
Interventions: DRUG: Sodium Chloride 0.9%|DRUG: Methylprednisolone acetate|PROCEDURE: Ultrasound-guided Needling and Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Safety and Immunogenicity of Live Attenuated Influenza H5 Candidate Vaccine Strain A/17/Turkey/Turkey/05/133 (H5N2) in Healthy Thai Volunteers
Status: COMPLETED
Conditions: Preventive Avian Flu
Interventions: BIOLOGICAL: Avian Flu Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Investigational Product MP-101 in Subjects With Short Bowel Syndrome Who Have Had an Inadequate Response to Anti-Diarrheals
Status: WITHDRAWN
Conditions: Short Bowel Syndrome|Short Gut Syndrome|SBS|Short Bowel|Short Gut
Interventions: DRUG: Opium Tincture USP Deodorized|DRUG: Opium Tincture USP Deodorized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SPN-812 (Viloxazine Extended-release Capsule) High Dose in Adolescents With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Placebo|DRUG: 400mg SPN-812|DRUG: 600mg SPN-812
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Metabolic Health Patterns And Breast Cancer Over Time in Women
Status: RECRUITING
Conditions: Cardiovascular Diseases|Cardiovascular Morbidity|Metabolic Disease
Interventions: BEHAVIORAL: Time restricted eating, nutrition education, and sedentary time reduction strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes
Status: RECRUITING
Conditions: Arteriosclerosis|Hypercholesterolaemia
Interventions: DRUG: Enlicitide Decanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
Status: RECRUITING
Conditions: Insomnia|Insomnia Chronic|Insomnia, Primary|Blood Pressure|Blood Pressure, High
Interventions: BEHAVIORAL: Cognitive Behavioral Treatment for Insomnia (CBT-I)|DRUG: Trazodone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD19-targeted CAR T Cells for Relapsed or Refractory (R/R) Large B-cell Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Large B-cell Lymphoma
Interventions: BIOLOGICAL: Relma-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How Elinzanetant Works and How Safe it is in Women Having Sleep Disturbances Associated With Menopause
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Disturbances Associated With Menopause
Interventions: DRUG: Elinzanetant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes of Rotator Cuff Repair With a Modified Versus Classic Double-Row Suture -Bridge Techniques
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: Rotator Cuff Repair With a Modified Versus Classic Double-Row Suture -Bridge Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Propofol Mixed With Remifentanil in Fiber Colonoscopyand Analgesia in Fiber Colonoscopy
Status: COMPLETED
Conditions: Narcotism
Interventions: PROCEDURE: Controlled analgesia/sedation|PROCEDURE: Intravenous combined anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Use of the Glidescope Cobalt to Direct Laryngoscopy in Infants
Status: COMPLETED
Conditions: Intubation
Interventions: DEVICE: Miller Laryngoscope|DEVICE: Glidescope Cobalt Video Laryngoscopes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Surgery; Gastric Bypass vs Sleeve Gastrectomy; Efects Over Type 2 DM With Bad Metabolic Control (MSO1CT)
Status: UNKNOWN
Conditions: Diabetes Mellitus|Metabolic Surgery|Sleeve Gastrectomy|BPGY
Interventions: PROCEDURE: metabolic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Status: COMPLETED
Conditions: Morton's Neuroma
Interventions: DRUG: CTNX-4975
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Newly-diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme of Brain
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy of Prasterone Treatment for Atrophy Vulvovaginal in Postmenopausal Women With Vulvar / Vestibular Pain
Status: UNKNOWN
Conditions: Vulvovaginal Atrophy
Interventions: DRUG: Prasterone 6.5 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once Daily Accelerated Fractionation With Concomitant Boost to the Gross Tumor Volume Compared With Twice Daily Hyperfractionation in Concurrent Chemoradiation in Patients With Limited Disease Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Limited Disease Small Cell Lung Cancer
Interventions: RADIATION: Arm 1: with twice-daily thoracic radiotherapy/ Arm 2: with once-daily thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Tolerability of Dupilumab (REGN668/SAR231893) in Patients Aged ≥6 to <18 Years With Atopic Dermatitis (Eczema)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTNS and PFR in the Treatment of Childhood Constipation
Status: COMPLETED
Conditions: Constipation|Childhood ALL|Pelvic Floor Disorders
Interventions: DEVICE: PTNS|DEVICE: Sham PTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Transcatheter Arterial Chemoembolization Versus Adjuvant Systemic Chemotherapy for Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: systemic chemotherapy|DRUG: Transcatheter Arterial Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SMS as an Incentive To Adhere (SITA) - An Intervention Communicating Social Norms by SMS to Improve ARV Adherence
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Own adherence|BEHAVIORAL: Own and group level adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty
Status: COMPLETED
Conditions: Total Hip and Knee Arthroplasties
Interventions: DRUG: Teicoplanin|DRUG: β-lactams or ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Insulin Action and Free Fatty Acids in Hyperandrogenism of Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Rosiglitazone|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kinesiotaping in Trauma
Status: NOT_YET_RECRUITING
Conditions: Fracture Rib|Acromioclavicular Joint Dislocation|Fracture Clavicle|Fracture, Proximal Humeral
Interventions: OTHER: Kinesio taping|OTHER: sham tape (leukotape classic)|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NKTR-255 in Relapsed/Refractory Multiple Myeloma & Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin Lymphoma|Indolent Non-Hodgkin Lymphoma
Interventions: DRUG: NKTR-255|DRUG: NKTR-255 Q21|DRUG: Rituximab|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0027: Vinorelbine Followed by Docetaxel in Treating Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Microtransplantation for in AML
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: hematopoietic stem cell microtransplantation-long-term|PROCEDURE: hematopoietic stem cell microtransplantation-short-term|DRUG: Conditioning for CR group|DRUG: Conditioning for Non-CR group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Resilience Clinic Evaluation
Status: RECRUITING
Conditions: Early Life Adversity|Caregiver Stress
Interventions: BEHAVIORAL: Resilience Clinic|BEHAVIORAL: Enhanced primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lispro Mix 25 vs. Glargine in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Insulin lispro mix 25|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Minocycline to Treat Children With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: minocycline hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Trial Assessing the Immunogenicity and Safety of Three Meningococcal B Vaccine Strategies Among Patients With Asplenia.
Status: RECRUITING
Conditions: Splenectomy
Interventions: BIOLOGICAL: Trumenba®|BIOLOGICAL: Bexsero®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The TMS Treatment for Postoperative Headache in GH Tumor
Status: UNKNOWN
Conditions: Headache|Pituitary Tumor|Acromegaly
Interventions: DEVICE: Transcranial magnetic stimulation|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Milk Protein Isolate (MPI)|DIETARY_SUPPLEMENT: Soy Protein Isolate (SPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing Guided Bone Regeneration by Modifying a Resorbable Membrane
Status: UNKNOWN
Conditions: Alveolar Ridge Augmentation
Interventions: OTHER: BioMend Extend|OTHER: Modified BioMend Extend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Stage IV|Pancreatic Cancer Metastatic
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel(Albumin Bound) and Gemcitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide Acupulse Laser Treatment Versus Sham Treatment and Stress Urinary Incontinence Symptoms
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: carbon dioxide laser|DEVICE: sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Peri-Implant Emergence Profile Conditioned With Two Different Prosthetic Techniques
Status: COMPLETED
Conditions: Dental Implants
Interventions: OTHER: Digitally Flip Technique|OTHER: Stock Healing Abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome, Adult|Ventilator-Induced Lung Injury
Interventions: DEVICE: Targeting transpulmonary pressure to avoid VILI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Efficacy Of PF-06826647 In Participants With Moderate To Severe Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: PF-06826647 100 mg QD|DRUG: PF-06826647 300 mg QD|DRUG: PF-06826647 600 mg QD|DRUG: Placebo|DRUG: PF-6826647 400 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of T-DXd Plus SRT in HER2-positive Breast Cancer Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Brain Metastases|Radiotherapy
Interventions: DRUG: Combination use of SRT with T-DXd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Multi-centre, Non-Inferiority Study of Safety and Immunogenicity of BIMERVAX for the Prevention of COVID-19 in Adolescents From 12 Years to Less Than 18 Years of Age.
Status: RECRUITING
Conditions: SARS CoV 2 Infection
Interventions: BIOLOGICAL: BIMERVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Total Marrow Irradiation for Refractory Acute Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome|Multiple Myeloma
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: Fludarabine|DRUG: mycophenolate mofetil|RADIATION: total marrow irradiation|PROCEDURE: umbilical cord blood transplantation|BIOLOGICAL: Granulocyte colony-stimulating factor|BIOLOGICAL: HLA-matched related donor bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Different Schedules of Carboplatin, Paclitaxel, Gemcitabine, and Surgery in Treating Patients With Newly Diagnosed Stage IIIC or Stage IV Primary Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mepolizumab in Severe Asthmatics on a Long Term (MESILICO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma; Eosinophilic|Severe Asthma|Late-Onset Asthma
Interventions: DRUG: Mepolizumab 100 MG [Nucala]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Double Blind, Randomized, Placebo Controlled Pilot Study to Evaluate the Effect of Nutritional Supplementation on Physical Activity Performance of Young Soccer Players
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutritional Supplementation|Growth
Interventions: DIETARY_SUPPLEMENT: Nutritional Sport Formula|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: AIR001 (sodium nitrite inhalation solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ad26.ZEBOV Booster in HIV+ Adults Previously Vaccinated With Ad26.ZEBOV/MVA-BN-Filo (EBOVAC HIV+ Booster Study)
Status: COMPLETED
Conditions: Ebola Virus Disease|Ebola|Hiv
Interventions: BIOLOGICAL: Ad26.ZEBOV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurosensory Assesment After Using Separators Vs Chisels in Bilateral Sagittal Split Mandibular Osteotomy. RCT
Status: UNKNOWN
Conditions: to Assess Neurosensory Function of Inferior Alveolar Nerve After BSSO
Interventions: PROCEDURE: bilateral sagittal split osteotomy using separators.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of the Cypher SES to Treat Restenotic Native Coronary Artery Lesions.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone for Term Hypotension
Status: COMPLETED
Conditions: Infant, Newborn, Diseases|Cardiovascular Insufficiency
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD30-directed Chimeric Antigen Receptor T (CART30) Therapy in Relapsed and Refractory CD30 Positive Lymphomas
Status: RECRUITING
Conditions: Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: CART30
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Clofarabine Study in Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bioavailability and Food Effect of SACT-1 and Edurant® Tablets in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: SACT-1|DRUG: EDURANT 25Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Cleft Repair Using Osteoinductive Ceramics
Status: RECRUITING
Conditions: Cleft Palate Children|Cleft Alveolar Ridge|Cleft Lip and Palate
Interventions: DEVICE: Unilateral alveolar cleft repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dysvascular Amputation Self-Management of Health
Status: RECRUITING
Conditions: Amputation|Diabetes Mellitus|Peripheral Artery Disease
Interventions: BEHAVIORAL: Walking Biobehavioral Intervention|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Customized Insoles for Individuals With Symptomatic Hallux Valgus
Status: NOT_YET_RECRUITING
Conditions: Hallux Valgus|Foot Diseases|Foot Deformities
Interventions: OTHER: Insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oropharyngeal Exercises on Patients With Primary Snore, Mild and Moderate Obstructive
Status: UNKNOWN
Conditions: Primary Snore, Obstructive Sleep Apnea (Mild and Moderate).
Interventions: BEHAVIORAL: Oropharyngeal exercises|BEHAVIORAL: Respiratory exercises, nasal dilator, nasal lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Human Mesenchymal Stem Cells (hMSCs) Infusion in Patients With Treatment Resistant Depression
Status: TERMINATED
Conditions: Treatment Resistant Depression
Interventions: DRUG: Allo-hMSCs|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Efficiency and Implementation of Cash Transfers to Improve Adherence to Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV/AIDS|Adherence, Medication|Adherence, Patient
Interventions: BEHAVIORAL: Active Arm 1|BEHAVIORAL: Active Arm 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Active Device (Torino II)|DEVICE: Sham Device (Torino II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study To Evaluate Multiple Doses of NT100 Following IVF In Women With Repeated IVF Failures (Thrive-IVF)
Status: COMPLETED
Conditions: Repeated IVF Failure
Interventions: DRUG: NT100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sympathetic Renal Denervation- a Study in Patients After Renal Transplantation
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Disease|Renal Transplantation|Sympathetic Activity
Interventions: DEVICE: Catheter-based renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT