pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Compare the Pharmacokinetics of Lafutidine and Irsogladine Maleate Tablet
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: BRI-1501|DRUG: Lafutidine|DRUG: Irsogladine maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Supplementation for Children With Drug Resistant Idiopathic Epilepsy
Status: COMPLETED
Conditions: Drug Resistant Epilepsy
Interventions: DIETARY_SUPPLEMENT: Magnesium|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AQCS for Detection of Early Cancer and Precancerous Lesions on Upper Gastrointestinal Tract
Status: COMPLETED
Conditions: Esophagogastroduodenoscopy
Interventions: DEVICE: Computer-aided Real-time Automatic Quality-control System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Leukocyte Depletion of Autologous Whole Blood
Status: COMPLETED
Conditions: Infection|Bacterial Infection|Sepsis
Interventions: PROCEDURE: leukocyte depletion of whole blood|OTHER: Leukocyte filtration/Depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Aspirin Response in Patients Undergoing Vascular Surgery
Status: COMPLETED
Conditions: Vascular Surgery Patient With PAD / Carotid Stenosis
Interventions: DRUG: Whole blood aggregometry before and after vascular treatment (ASA/ Clopidogrel).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD
Status: RECRUITING
Conditions: Gastroesophageal Reflux
Interventions: DRUG: MHS-1031|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels
Status: COMPLETED
Conditions: Aggressive Periodontitis
Interventions: PROCEDURE: SRP+940±15 nm diode laser|PROCEDURE: SRP+Er,Cr:YSGG laser|PROCEDURE: Scaling and root planing (SRP)-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endostar Combined With Intensity-modulated Radiotherapy Compare With Chemoradiation for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: endostar|DRUG: DDP|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Strategy Based on Ultrasound Lung Morphology in Patients With Focal ARDS
Status: RECRUITING
Conditions: Focal Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: LUVS" ventilatory strategy composed of a bundle of measures|PROCEDURE: Ventilatory management according to international recommendations (Société de Réanimation de la Langue Française)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Subjects
Status: COMPLETED
Conditions: Dengue Virus|Dengue Fever|Dengue Hemorrhagic Fever|Dengue Disease
Interventions: BIOLOGICAL: CYD dengue vaccine serotypes (1, 2, 3, 4).|BIOLOGICAL: Meningococcal Polysaccharide A+C; NaCl; Typhoid Vi polysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reinforcement of the Abdominal Wall After Breast Reconstruction With the Pedicled TRAM-flap
Status: COMPLETED
Conditions: Abdominal Donor-site
Interventions: DEVICE: Biological mesh|DEVICE: Synthetic mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Preference, Satisfaction And Correct Use Of Inhalers In COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Tiotropium|DRUG: Indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Assessing the Effects of PXT00864 in Patients With Mild Alzheimer Disease (AD)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: PXT00864|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Tolerability and Pharmacokinetics of IBI112 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: IBI112 dose1|DRUG: IBI112 dose2|DRUG: IBI112 dose3|DRUG: IBI112 dose4|DRUG: IBI112 dose5|DRUG: IBI112 dose6|DRUG: IBI112 dose7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Glargine v Rosiglitazone as add-on Therapy in Patients Failing Sulfonylurea and Metformin Combination Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: insulin glargine|DRUG: rosiglitazone|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Scaling and Root Planing on Oral Inflammatory Biomarkers Among E-cig Users and Non-smokers
Status: COMPLETED
Conditions: Periodontal Diseases|Smoking
Interventions: PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gaze-Contingent Music Reward Treatment for PTSD
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: OTHER: Placebo GC-MRT|OTHER: GC-MRT|OTHER: Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Definitive CCRT for LACC Patients
Status: RECRUITING
Conditions: Cervical Cancer|Chemoradiotherapy|Immunotherapy
Interventions: DRUG: Toripalimab|RADIATION: CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effect of SB3 and Herceptin® in Women With HER2 Positive Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Early or Locally Advanced Breast Cancer
Interventions: DRUG: Herceptin (trastuzuamb)|DRUG: SB3 (proposed trastuzumab biosimilar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myobloc Atrophy Study
Status: COMPLETED
Conditions: Spasticity Secondary to Either a Disorder or Trauma|Spinal Cord Injury (SCI)|Brain Injury|Tumor|Stroke
Interventions: DRUG: Botox|DRUG: MYOBLOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MicrOwave and laSer ablaTion Study (MOST Study)
Status: UNKNOWN
Conditions: Varicose Veins of Lower Limb
Interventions: DEVICE: Microwave Ablation Therapeutic Apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Disorders in Patients With Multiple Sclerosis: Invasive Vs Non-invasive Investigations.
Status: UNKNOWN
Conditions: Multiple Sclerosis|Urinary Bladder, Neurogenic|Urodynamics
Interventions: DIAGNOSTIC_TEST: Non-invasive investigations|DIAGNOSTIC_TEST: Invasive investigations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A FIH Study of YH35324 in Atopic Healthy Subjects or Subjects With Mild Allergic Diseases
Status: COMPLETED
Conditions: Atopic Healthy Subjects|Adult Subjects With Mild Allergic Diseases
Interventions: DRUG: YH35324|DRUG: Placebo|DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial of GlivecWith Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Radiotherapy Versus Radiofrequency Ablation for Patients With Medium or Large Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: RADIATION: Proton radiotherapy|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Granulomatosis With Polyangiitis|Wegener Granulomatosis|Vasculitis
Interventions: DRUG: 5 mg prednisone|DRUG: 0 mg prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prognostic Value of Biological Markers, Coll2-1 and Coll2-1NO2 in Patients With Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Serum and urine samples collections|OTHER: Imaging (x-rays and MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Versus Inmediately Skin to Skin Contact in Cesarean Section
Status: UNKNOWN
Conditions: Breastfeeding, Exclusive|Mother-Child Relations|Kangaroo-mother Care
Interventions: PROCEDURE: Early SCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of a Teleconsultation Performed During Ambulance's Displacement
Status: COMPLETED
Conditions: Patients Emergency On-site Care by Mobile Emergency Unit
Interventions: DIAGNOSTIC_TEST: No teleconsultation during the ambulance journey|DIAGNOSTIC_TEST: Teleconsultation during the ambulance journey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Somatostatin Prevent Post-operation Pancreatic Fistula in Intermediate Risk Patients After Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: DRUG: Somatostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function
Status: COMPLETED
Conditions: PK of FG-4592|Hepatic Insufficiency|Healthy Subjects
Interventions: DRUG: FG-4592
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Prehabilitation Improve Exercise Performance and Insulin Resistance After Surgery for Oesophago-gastric Cancer?
Status: UNKNOWN
Conditions: Cancer
Interventions: BEHAVIORAL: Prehabilitation|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare 3 Doses of a Hormonal Intra-uterine Device Containing Levonorgestrel and Indomethacin With a Hormonal Intra-uterine Device Containing Only Levonorgestrel to Assess the Effect and Safety of the Combined Components
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: BAY98-7443|DRUG: Levonogestrel (Skyla, BAY86-5028)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Type II Diabetes Mellitus
Interventions: DRUG: Beetroot Juice (Beet-It Stamina Shot) and Exercise Training|OTHER: Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection
Interventions: DRUG: CXA-101|DRUG: Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Placebo|DRUG: Eligard 22.5Mg Suspension for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation
Status: COMPLETED
Conditions: Opioid-Induced Constipation (OIC)
Interventions: DRUG: NKTR-118|DRUG: NKTR-118|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial.
Status: RECRUITING
Conditions: Hypoplastic Left Heart Syndrome
Interventions: BIOLOGICAL: Lomecel-B medicinal signaling cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Nalbuphine and Dexmedetomidine Versus Sufentanil and Dexmedetomidine on Patients
Status: RECRUITING
Conditions: Laparoscopic|Gastrointestinal Surgery
Interventions: PROCEDURE: nalbuphine group|PROCEDURE: sufentanil group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: One vs Two Weeks Treatment for H.Pylori Eradication A RANDOMIZED NON-INFERIORITY PLACEBO CONTROLLED TRIAL
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan, Amoxicillin, Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Full4Health: Understanding Food-gut-brain Axis Across the Lifecourse
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Breakfast Study|OTHER: fMRI Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Study Intubation Rates of Non-invasive Ventilation Using Pressure Support Ventilation (PSV) Versus Adaptive Support Ventilation (ASV) Mode in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Invasive Mechanical Ventilation|Adaptive Support Ventilation
Interventions: OTHER: Adaptive support ventilation|OTHER: Pressure support ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy
Status: NOT_YET_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: NM8074
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo
Status: COMPLETED
Conditions: Nausea|Vomiting|Vertigo
Interventions: DRUG: Dimenhydrinate|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia
Status: RECRUITING
Conditions: Beta-Thalassemia
Interventions: DRUG: ACE-536
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19
Status: COMPLETED
Conditions: Mild-to-moderate COVID-19
Interventions: OTHER: KB109 + Self Supportive Care (SSC)|OTHER: Self Supportive Care (SSC) Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma
Status: RECRUITING
Conditions: Monoclonal Gammopathy of Undetermined Significance (MGUS)|Smoldering Multiple Myeloma (SMM)
Interventions: DRUG: Linvoseltamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Adjuvants for Intracellular Nutrition and Treatment
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema
Interventions: DRUG: Neutral pills with no medicinal effect|DIETARY_SUPPLEMENT: Inosine; Tocopherols, Tocotrienol, CoQ10 combination capsule; Niacinamide SR; Viatmin C; N-acetyl Cysteine; Complete Multivitamin with all minerals|DRUG: Inosine; Tocopherol, Tocotrienol, CoQ10 combination capsule; Niacinamide; Vitamin C; N-acetyl Cysteine; Complete Multivitamin with all minerals; Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: CCRT+Nimotuzumab|DRUG: CCRT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MLD10 for the Treatment of Hypomagnesemic Patients With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Hypomagnesemia in Type 2 Diabetic Patients
Interventions: DRUG: Magnesium L-lactate dihydrate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caffeine to Reduce Mechanical Ventilation in Preterm Infants
Status: TERMINATED
Conditions: Prematurity|Apnea|Respiratory Failure
Interventions: DRUG: Caffeine citrate|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of 7-Keto on Resting Metabolic Rate in Overweight Adults
Status: COMPLETED
Conditions: Resting Metabolic Rate|Overweight Subjects
Interventions: DIETARY_SUPPLEMENT: 7-Keto 50mg|DIETARY_SUPPLEMENT: 7-Keto 25mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Viagenpumatucel-L|DRUG: Metronomic Cyclophosphamide|DRUG: Physician's Choice Regimen (Vinorelbine, Erlotinib, Gemcitabine, Paclitaxel, Docetaxel, Pemetrexed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Artery Embolization for Symptomatic Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: PROCEDURE: Prostate artery embolization (PAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Toronto Prehospital Hypertonic Resuscitation Head Injury and Multi Organ Dysfunction Trial (TOPHR HIT)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BIOLOGICAL: hypertonic saline mixed Dextran|BIOLOGICAL: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy
Status: TERMINATED
Conditions: Lung Neoplasms|Thoracic Neoplasms|Neoplasms by Site|Neoplasms|Lung Diseases
Interventions: DEVICE: MIMIG System|DRUG: Indocyanine Green (ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An AI-Based CDSS for Integrated Management of Patients With Acute Ischemic Stroke(GOLDEN BRIDGE II)
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: AI-based CDSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Pharmacokinetics of Gefapixant (MK-7264) in Participants With Renal Insufficiency (MK-7264-026)
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: Gefapixant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety of Immediate One-stage IBBR With Expander-Implant Two-stage IBBR Augmented With TiLoop® Bra(COSTA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Immediate IBBR+TiLoop®Bra|PROCEDURE: Immediate-delayed IBBR+TiLoop®Bra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegzilarginase in Subjects &lt;24 Months Old With Arginase 1 Deficiency
Status: NOT_YET_RECRUITING
Conditions: Arginase 1 Deficiency
Interventions: DRUG: Pegzilarginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants.
Status: TERMINATED
Conditions: Bacteremia|Infant, Very Low Birth Weight
Interventions: DEVICE: Edelvaiss Multiline NEO|DEVICE: Standard Infusion Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A See and Treat Paradigm for Cervical Pre-cancer
Status: TERMINATED
Conditions: Cervical Pre-cancer
Interventions: DEVICE: transvaginal digital colposcope (TVDC)|OTHER: Standard of care screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Online and Recovery-oriented Peer Support Groups Facilitated by Peer Support Workers in Times of COVID-19
Status: UNKNOWN
Conditions: Psychotic Disorders|Anxiety Depression
Interventions: BEHAVIORAL: Transitional Online Peer Support Group (n=20)|OTHER: Control Group (pharmacotherapy and/or psychotherapy, n=10)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRISM-GENOMICS-Smoking Cessation for Patients With Coronary Artery Disease Undergoing Cardiac Catheterization or Having a Heart Attack at Barnes Hospital in St. Louis Mo
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Smoking Cessation
Interventions: OTHER: genotype-guided therapy|DRUG: Nicotine patch|BEHAVIORAL: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous Platelet-rich Plasma to Improve Responsiveness and Embryo Quality in Patients With Poor Ovarian Response
Status: UNKNOWN
Conditions: Infertility
Interventions: BIOLOGICAL: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guided Radiofrequency Ablation Using the CARTO® 3 and NavX™ Systems for the Treatment of Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Cardiac Mapping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transversalis Fascia Plane Blocks for Analgesia Post-cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Delivery
Interventions: DEVICE: ultrasound-guided nerve block|DRUG: Saline|DRUG: Bupivacaine-epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Assessing Efficacy and Safety of Asciminib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase.
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer
Status: TERMINATED
Conditions: Advanced Colorectal Adenomas|Adenocarcinoma of the Colon|Stage I Colon Cancer|Stage II Colon Cancer|Stage III Colon Cancer
Interventions: DRUG: defined green tea catechin extract|OTHER: placebo|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Smart Self-Management Support Programme (3S) to Improve Quality of Life in Lung Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: 3S intervention|BEHAVIORAL: GH information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics, Safety and Tolerability of Tamsulosin Hydrochloride in Children With Voiding Disorders
Status: COMPLETED
Conditions: Urination Disorders
Interventions: DRUG: Tamsulosin hydrochloride, very low dose|DRUG: Tamsulosin hydrochloride, low dose|DRUG: Tamsulosin hydrochloride, medium dose|DRUG: Tamsulosin hydrochloride, high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Portable Tonometers (Icare Pro, TONO-Pen AVIA, Perkins Tonometer, PASCAL Hand Held Dynamic Contour Tonometer)
Status: UNKNOWN
Conditions: Healthy Participants
Interventions: DEVICE: measurement of intraocular pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy
Status: RECRUITING
Conditions: Adrenalectomy
Interventions: PROCEDURE: laparoscopic transabdominal adrenalectomy|PROCEDURE: robotic transabdominal adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Rehabilitation After Occipital Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic|Quadrantanopia|Vision Loss Partial|Visual Field Defect, Peripheral|Peripheral Visual Field Defect of Both Eyes|Peripheral Visual Field Defect|Hemianopsia|Hemianopia|Homonymous Hemianopia|Homonymous Hemianopsia|Visual Fields Hemianopsia|Occipital Lobe Infarct|Quadrantanopsia|Stroke Hemorrhagic
Interventions: DEVICE: Subacute Training in the intact field|DEVICE: Subacute Training in the blind field|DEVICE: Chronic Training in the blind field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.
Status: COMPLETED
Conditions: Supraventricular Arrhythmias
Interventions: OTHER: Evaluation of the relationship between atrial remodeling evaluated by ECG and ETT with the occurrence of supraventricular arrhythmias
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effects of Retro Laminar Block (RLB) and Erector Spina Area Block (ESP) on Postoperative Recovery Quality and Pain in Lumbar Spinal Surgery
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector spina area block|PROCEDURE: Retrolaminar block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEEL Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor 60|DRUG: Ticagrelor 90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERP to Improve Functioning in Veterans With OCD
Status: RECRUITING
Conditions: Obsessive Compulsive Disorder (OCD)|Comorbid Post-Traumatic Stress Disorder and OCD
Interventions: BEHAVIORAL: Exposure and Response Prevention|OTHER: Stress Management Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hip Abductors Strengthening In Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis Knees Both
Interventions: OTHER: Hip Abductor Strengthening|OTHER: Traditional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of ANAVEX2-73 in Patients With Rett Syndrome
Status: COMPLETED
Conditions: Rett Syndrome
Interventions: DRUG: ANAVEX2-73|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in Adult Participants With Muscular Dystrophy
Status: COMPLETED
Conditions: Facioscapulohumeral Muscular Dystrophy (FSHD)
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: ATYR1940
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Management of Femoroacetabular Impingement
Status: COMPLETED
Conditions: Femoroacetabular Impingement
Interventions: OTHER: Manual therapy plus exercise|OTHER: Advice and home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gross Examinations Versus Frozen Section for Assessment of Surgical Margins in Oral Cancers
Status: RECRUITING
Conditions: Oral Cavity Cancer
Interventions: PROCEDURE: Gross examination of the resection specimen|PROCEDURE: Frozen section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF Value
Status: UNKNOWN
Conditions: Peritoneal Dialysis Complication|Hemodialysis Complication|Heart Failure
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet|DRUG: RAS Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Status: COMPLETED
Conditions: Bimalleolar Fractures of the Ankle.|Sciatic Nerve Block.|Saphenous Nerve Block.|Post Operative Analgesia Duration.
Interventions: DRUG: Bupivacaine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Study in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Rotigotine Transdermal Patch in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rotigotine, Period 1|DRUG: Rotigotine, Period 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Bumetanide in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Bumetanide white, oblong, scored tablet|DRUG: Placebo white, oblong, scored tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactions
Status: RECRUITING
Conditions: IgE-mediated Abdominal Pain
Interventions: DRUG: Salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Furosemide vs. Placebo for Severe Antepartum Hypertension
Status: COMPLETED
Conditions: Pre-Eclampsia|Hypertension in Pregnancy|Pregnancy Complications|Hypertension, Pregnancy-Induced
Interventions: DRUG: Furosemide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
Status: COMPLETED
Conditions: Depression|Anxiety|Major Depressive Disorder|Generalized Anxiety Disorder|Mood Disorders
Interventions: OTHER: Pharmacogenomic Testing|OTHER: Pharmacist Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparision of Clinical Efficacy of Immediate Implants With T-PRF and Bone-graft Versus PRF and Bone-graft
Status: NOT_YET_RECRUITING
Conditions: Dental Implants
Interventions: PROCEDURE: Immediate implant surgery with T-PRF and xenograft|PROCEDURE: Immediate implant surgery with PRF and xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Pain Care During Complex Wound Care Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Wound Surgical|Wounds and Injuries|Virtual Reality|Wound Care|Music Therapy
Interventions: DEVICE: Virtual Reality system|OTHER: Headphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VASCULAR AND RENAL IMPACT OF ENDOTHELIN-1 RECEPTOR BLOCKADE IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION
Status: UNKNOWN
Conditions: Resistant Hypertension
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Virtual Reality on Functional Mobility During Treadmill Training in Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Treadmill training with virtual reality|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer
Status: WITHDRAWN
Conditions: Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: BIOLOGICAL: ziv-aflibercept|DRUG: leucovorin calcium|DRUG: fluorouracil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor|Refractory Hodgkin Lymphoma
Interventions: DRUG: HCB301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Clevudine Compared With Clevudine and Vaccine in Patient With HBeAg(+) Chronic HBV
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Clevudine|BIOLOGICAL: Purified hepatitis B surface antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)
Status: COMPLETED
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Nintedanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: PROCEDURE: 6 to 9 ultraviolet B treatments|PROCEDURE: Skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin controlled release, 330 mg, 400 to 500 calorie|DRUG: Pregabalin controlled release, 330 mg, 600- 750 calorie|DRUG: Pregabalin controlled release, 330 mg, bedtime|DRUG: Pregabalin immediate release, 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Assessment of Indirect Restoration Fabricated From Nano Hybrid Composite Blocks Versus Ceramic Blocks in Badly Broken Teeth One Year Follow up
Status: UNKNOWN
Conditions: Teeth Restoration
Interventions: DRUG: composite blocks|DRUG: ceramic cad cam blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Background of Endothelial Cell Loss in Patients With Phakic Intraocular Lenses: a Tear and Aqueous Humour Analysis Study
Status: RECRUITING
Conditions: Cataract|Phakic Intraocular Lens Explantation
Interventions: PROCEDURE: Phakic intraocular lens (pIOL) explantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics Study of Intranasal Ketorolac in Elderly and Nonelderly Adult Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Ketorolac tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to Reduce Suicide Risk (R-Vets Sleep)
Status: COMPLETED
Conditions: Insomnia|Mental Health Functioning|Physical Health Functioning
Interventions: BEHAVIORAL: Computerized Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Comparison of the Octaray and Pentaray Catheters
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: OTHER: Left atrial mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study in Volunteers From 16 to 65 Years of Age: FSME IMMUN NEW vs. ENCEPUR
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Effectiveness of Acceptance Commitment Therapy or Micro Breaks in Patients With Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis
Status: RECRUITING
Conditions: Fatigue Syndrome, Chronic
Interventions: BEHAVIORAL: Acceptance Commitment Therapy for chronic fatigue|BEHAVIORAL: Micro breaks in everyday life for chronic fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Conscripts
Status: COMPLETED
Conditions: Vitamin D Deficiency|Military Activity
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (1200 IU/30µg)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Consistency of Questionnaires to Evaluating Sexual Functions in Young Healthy Women
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological|Sexual Dysfunctions, Psychological|Physical Activity
Interventions: OTHER: Exercise program for pelvic muscle floor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION