pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of High Dose Vitamin D Supplementation on HIV Latency
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Vitamin D3, 10000 Intl Units Oral Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vedolizumab (MLN0002) in Patients With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: vedolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)
Status: TERMINATED
Conditions: Type2 Diabetes|Dyslipidemia
Interventions: DRUG: K-877|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of PRRT in Metastatic, World Health Organization (WHO) Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgery
Status: RECRUITING
Conditions: Gastroenteropancreatic Neuroendocrine Tumor
Interventions: DRUG: Lutathera|DRUG: Gallium 68 Dotatate|PROCEDURE: Computed Tomography (CT)|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biventricular Pacing After Coronary Artery Bypass Grafting (BIVAC)
Status: COMPLETED
Conditions: Cardiac Pacing,Artificial|Coronary Artery Bypass|Ventricular Function, Left
Interventions: PROCEDURE: Postoperative Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Twice Weekly VELCADE and CAELYX in Patients With Ovarian Cancer Failing Platinum Containing Regimens
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: bortezomib|DRUG: pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease
Status: COMPLETED
Conditions: Healthy Volunteers|Anemia, Sickle Cell
Interventions: DRUG: AG-946|DRUG: AG-946 Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis
Status: COMPLETED
Conditions: Quadriplegia|Spinal Cord Injury|ALS
Interventions: PROCEDURE: Tongue Piercing|DEVICE: Usability assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Comparing the PICOPREP Tailored Dosing Schedule to the PICOPREP Day-before Dosing Schedule for Colon Cleansing in Preparation for Colonoscopy
Status: COMPLETED
Conditions: Bowel Cleansing
Interventions: DRUG: PICOPREP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Inferior Submucosal Turbinectomy Versus Blunt Turbinectomy for Inferior Turbinate Hypertrophy
Status: UNKNOWN
Conditions: Bilateral Inferior Turbinates Hypertrophy
Interventions: PROCEDURE: bilateral nasal inferior turbinectomy|PROCEDURE: endoscopic submucosal resection of the inferior turbinates
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developmental Intervention for Infants of Adolescent Mothers
Status: COMPLETED
Conditions: Development, Child|Adolescent Behavior|Language Development|Language Delay
Interventions: BEHAVIORAL: Teaching Talking|BEHAVIORAL: LENA recordings-language|BEHAVIORAL: LENA recordings-motor|BEHAVIORAL: Mastering Movement|BEHAVIORAL: Language text messages|BEHAVIORAL: Motor text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EW-A-401 to Treat Intermittent Claudication
Status: COMPLETED
Conditions: Intermittent Claudication|Arteriosclerosis
Interventions: DRUG: DNA Plasmid Vector|DRUG: EW-A-401 DNA Plasmid Vector
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Cardioneuroablation to Permanent Pacing in Patients With an Implanted Pacemaker for Symptomatic Bradycardia.
Status: RECRUITING
Conditions: Bradycardia|Syncope
Interventions: DIAGNOSTIC_TEST: Invasive electrophysiological study|DIAGNOSTIC_TEST: Extracardiac vagal stimulation|PROCEDURE: Cardioneuroablation|PROCEDURE: Redo cardioneuroablation|PROCEDURE: Implantation of the implantable loop recorder|DIAGNOSTIC_TEST: Pacemaker check|DIAGNOSTIC_TEST: Implantable loop recorder check|DIAGNOSTIC_TEST: Holter ECG|DIAGNOSTIC_TEST: Anamnesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: glucosamine sulphate 1500mg and meloxicam 15mg|DRUG: Glucosamine sulfate 1500mg and chondroitin sulfate 1200mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery
Status: UNKNOWN
Conditions: Neoplasm|Diverticular Disease|Analgesia
Interventions: PROCEDURE: epidural|PROCEDURE: PCA|PROCEDURE: Spinal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of BMS-986012 in Combination With Platinum and Etoposide
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: BMS-986012|DRUG: Cisplatin|DRUG: Etoposide|DRUG: Platinum|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal-directed Mobilization of Medical Inpatients
Status: COMPLETED
Conditions: Immobility Syndrome|Fall|Delirium|Sarcopenia|Mobility Limitation|Hospital Acquired Condition
Interventions: BEHAVIORAL: Goal-directed mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving the Cognitive Accessibility of Self-reports for People With ID
Status: COMPLETED
Conditions: Mild Intellectual Disability|Borderline Intellectual Functioning
Interventions: DIAGNOSTIC_TEST: Adaptive functioning self-report questionnaire|DIAGNOSTIC_TEST: Adaptive functioning self-report questionnaire - adapted
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Type 1 Diabetes, Exercise and Mentoring Trial
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes|Physical Activity
Interventions: BEHAVIORAL: 12-week TEAM peer mentor program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Strategy of Surgical Resection With Adjuvant Therapy for IIIA NSCLC and N2 Disease Only in Subaortic or Paraaortic Level
Status: UNKNOWN
Conditions: Lung Cancer|Cancer of Lymph Node|Effects of Chemotherapy|Surgery
Interventions: PROCEDURE: Primary surgical resection with sequential adjuvant therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tailored Activity Goals - an Exercise Prescription Study
Status: COMPLETED
Conditions: Physical Activity|Affect
Interventions: BEHAVIORAL: Positive Affect Condition|BEHAVIORAL: Negative Affect Condition|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurotensin - an Important Regulator of Appetite in Humans?
Status: UNKNOWN
Conditions: Physiology - Regulation of Appetite and Food Intake
Interventions: OTHER: Neurotensin|OTHER: Saline|OTHER: Ad libitum meal|OTHER: Liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease (SCD)
Interventions: DRUG: ALXN1820
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brachial Plexus Birth Palsy: Reinforcement Paradigm to Augment Recovery
Status: UNKNOWN
Conditions: Brachial Plexus Palsy
Interventions: BEHAVIORAL: Triggered reinforcement|BEHAVIORAL: Social interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refractory Peripheral T-Cell Lymphoma (VALENTINE-PTCL01)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Peripheral T-Cell Lymphoma|Adult T Cell Leukemia/Lymphoma
Interventions: DRUG: Valemetostat Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of Anus-preservation in Low Rectal Adenocarcinoma Based on MMR/MSI Status
Status: RECRUITING
Conditions: Toripalimab|Radiation
Interventions: DRUG: Toripalimab|RADIATION: CRT|RADIATION: SCRT|DRUG: XELIRI|DRUG: FOLFRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Monoclonal Antibody Therapy in Treating Women With Stage II or Stage IIIA Breast Cancer That Overexpresses HER2
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Memory Intervention for Individuals With Traumatic Brain Injury
Status: UNKNOWN
Conditions: Brain Injuries, Traumatic|Brain Injury Traumatic Severe|Brain Injury Traumatic Moderate|Brain Injury, Chronic
Interventions: BEHAVIORAL: Spatial Navigation Intervention|BEHAVIORAL: Educational Videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Cytomegalovirus
Interventions: BIOLOGICAL: mRNA-1647|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Residential Cleaning of Indoor Air to Protect COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: HEPAirX air filter|DEVICE: control air filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Pre-washing the Insemination Catheter on Pregnancy Outcome
Status: TERMINATED
Conditions: Infertility|Pregnancy
Interventions: OTHER: washing the insemination catheter with sperm washing media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploring the Efficacy and Safety of Rivaroxaban to Support Elective Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Cardiovascular Disease|Coronary Artery Disease
Interventions: DRUG: UFH|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939) and UFH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism
Status: RECRUITING
Conditions: Secondary Hyperparathyroidism;Parathyroidectomy
Interventions: PROCEDURE: Parathyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Corneal Abrasions With Topical Tetracaine
Status: UNKNOWN
Conditions: Corneal Abrasion
Interventions: DRUG: Ophthalmic Tetracaine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STylet-driven vs. LumenlEss Lead in Left-Bundle-Branch Pacing
Status: RECRUITING
Conditions: Left Bundle-Branch Pacing
Interventions: DEVICE: Pacemaker implantation with conduction system pacing using Lumenless leads|DEVICE: Pacemaker implantation with conduction system pacing using Stylet-driven leads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimating Prevalence of Inherited Disorders of Sulfur Amino Acids Metabolism in Patients With Psychotic Disorders.
Status: RECRUITING
Conditions: Inherited Metabolic Disorder of Nervous System|Schizophrenia
Interventions: DIAGNOSTIC_TEST: Sulfitest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ
Status: RECRUITING
Conditions: DCIS|Breast Cancer|Breast Neoplasms|Sentinel Lymph Node
Interventions: DIAGNOSTIC_TEST: Delayed SLND|DIAGNOSTIC_TEST: Late SLND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Verticalization in neuroICU With ERIGO: a Safety and Feasibility Study
Status: COMPLETED
Conditions: Brain Injury
Interventions: OTHER: Early rehabilitation treatment on Erigo Hocoma|OTHER: Early rehabilitation treatment on Erigo Hocoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Venetoclax as Single Agent in Patients With Relapsed/Refractory BCL-2 Positive Peripheral T Cell Lymphoma
Status: TERMINATED
Conditions: T-Cell Lymphoma Relapsed|T-Cell Lymphoma Refractory
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inulin on Iron Absorption in Humans
Status: COMPLETED
Conditions: Iron Absorption|Gut Bacteria
Interventions: DIETARY_SUPPLEMENT: inulin|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multi-center Phase III Randomized Controlled Trial
Status: UNKNOWN
Conditions: Carcinoma，Non-Small-Cell Lung
Interventions: DRUG: cisplatin and pemetrexed|DRUG: nedaplatin+pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Recombinant Listeria Monocytogenes(Lm)Based Vaccine Virus Vaccine to Treat Oropharyngeal Cancer
Status: TERMINATED
Conditions: HPV-16 +ve Oropharyngeal Carcinoma
Interventions: BIOLOGICAL: ADXS11-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Diazepam for the Treatment of Female Pelvic Pain
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Pelvic Pain
Interventions: DRUG: Diazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Immunogenicity of Pediacel™ and Infanrix™ IPV+Hib (Penta) Given in a 3 Dose Schedule in Infants
Status: COMPLETED
Conditions: Pertussis|Diphtheria|Tetanus|Poliomyelitis|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: DT5aP-IPV-Hib 5-component Pertussis vaccine|BIOLOGICAL: Infanrix® -IPV+Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 'A Profile of Physical Performance Variables in an Out-patient Adult Population With Narcolepsy'
Status: SUSPENDED
Conditions: Narcolepsy|Narcolepsy 1|Narcolepsy Type 1|Narcolepsy With Cataplexy|Narcolepsy Without Cataplexy|Narcolepsy and Hypersomnia|Hypersomnolence
Interventions: OTHER: Assessment of physical performance variables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Use of 2% Chlorhexidine Gluconate With Mineral Trioxide Aggregate in Indirect Pulp Treatment of Primary Molars
Status: COMPLETED
Conditions: Indirect Pulp Treatment
Interventions: OTHER: 2% chlorhexidine gluconate with mineral trioxide aggregate.|OTHER: Mineral trioxide aggregate.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Six Months of Moderate Resistance- Versus Endurance-Training on Muscle ATP Synthesis in First-Degree Relatives of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Insulin Resistance
Interventions: BEHAVIORAL: exercise training, endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
Status: COMPLETED
Conditions: Coping Behavior|Emotional Distress|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Art therapy - pre and post test measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Retrospective, Real-world Study of ELP Used in the Expectorant Treatment of Community-acquired Pneumonia
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Eucalyptol, Limonene and Pinene Enteric Soft Capsule|DRUG: Ambroxol injection|DRUG: Other oral mucolytic drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate How the Study Drug SHP626 is Eliminated From the Body After One Dose
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DRUG: SHP626|RADIATION: 5.95 μCi RAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of the Sternal Patch System With a Conventional Holter Recorder
Status: UNKNOWN
Conditions: Cardiac Arrhythmia|Syncope
Interventions: DEVICE: CarnationTM Ambulatory Monitoring Sternal ECG Patch System|DEVICE: Conventional 24-Hour 7 Lead Holter Monitor Recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endosseous Oroantral Port for Minimal Intervention in Treating Chronic Sinusitis
Status: UNKNOWN
Conditions: Maxillary Sinusitis
Interventions: PROCEDURE: treatment of chronic maxillary sinusitis using DIVA system|DEVICE: "dynamic implant valve approach" - DIVA system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telaprevir, Peg-IFN-alfa-2a, and RBV in Treatment-Experienced Black/African American and Non-Black/African American Subjects With Genotype 1 Chronic Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: Ribavirin|BIOLOGICAL: Pegylated Interferon Alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin Hydrochloride ER Tablets 500 mg|DRUG: Glucophage® XR 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders
Status: RECRUITING
Conditions: Eating Disorders|Anorexia Nervosa
Interventions: BEHAVIORAL: Open weighing|BEHAVIORAL: Blind weighing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chromocolonoscopy for the Detection of Flat Adenomas in Routine Colorectal Cancer Screening.
Status: COMPLETED
Conditions: Colon Cancer|Polyp|Adenoma
Interventions: PROCEDURE: Chromocolonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Set-up Reproducibility Between Prone and Supine Intensity Modulated Radiotherapy (IMRT) for the Adjuvant Treatment of Breast Carcinoma After Lumpectomy
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: BEHAVIORAL: prone and supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Endpoint Bioequivalence Study of Test and Reference Inhalation Products in Patients With COPD With Device Robustness
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Placebo|DRUG: Test Product (tiotropium bromide inhalation powder)|DRUG: Reference Product (Spiriva®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate RCN3028 in Treatment of Drug-Induced VMS in Breast Cancer
Status: TERMINATED
Conditions: Hot Flashes|Breast Cancer
Interventions: DRUG: 0.8 mg RCN3028|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Exparel to Bupivacaine With Dexamethasone in TAP Block
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Bupivacaine Extended-Release Liposome Injection (Exparel)|DRUG: Bupivacaine and Dexamethasone Injection|DRUG: IV Acetaminophen|DRUG: Oral Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scoring Balloon and High Pressure Balloon in the Treatment of Arteriovenous Graft Stenosis
Status: NOT_YET_RECRUITING
Conditions: Arteriovenous Graft Stenosis
Interventions: DEVICE: DKutting PTA Scoring Balloon Dilatation Catheter|DEVICE: Peripheral Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Trial to Evaluate an Automated Cerebral Ventricular Drainage System in Patients in the Neurointensive Care
Status: UNKNOWN
Conditions: ICP Regulation Using a New Device for Automated Zero-calibration for a Ventricular Drainage System
Interventions: DEVICE: Vguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Bilateral Quadratus Lumborum Block in the End of Colorectal Laparosopic Surgery.
Status: COMPLETED
Conditions: Post Operative Pain|Laparoscopic Colorectal Surgery
Interventions: PROCEDURE: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Combination Ambrisentan and Tadalafil in Patients With Portopulmonary Hypertension
Status: WITHDRAWN
Conditions: Portopulmonary Hypertension|Pulmonary Hypertension|Cirrhosis, Liver
Interventions: DRUG: Ambrisentan Pill|DRUG: Tadalafil Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using 32 - Gauge Needles With Lengths of 5 mm and 8 mm on Pain Post-injection, Leak and Blood Glucose
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: 5-mm 32-gauge Insulin needles in the first three days of Intervention|DEVICE: 8-mm 32-gauge Insulin needles in the first three days of Intervention|DEVICE: 5-mm 32-gauge Insulin needles in the last three days of Intervention|DEVICE: 8-mm 32-gauge Insulin needles in the last three days of Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-Drug Interaction Study in Trans Women Living With HIV
Status: RECRUITING
Conditions: Hiv|Transgenderism
Interventions: DRUG: Biktarvy 50/200/25 Tab|DRUG: Estradiol Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Long-term Exercise on Haemostasis and Inflammation in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Exercise|Inflammation|Hemostasis
Interventions: OTHER: Long-term exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Blue Cap for the Treatment of Atopic Dermatitis in Children
Status: COMPLETED
Conditions: Atopic Dermatitis|Atopic Dermatitis and Related Conditions|Atopic Dermatitis Eczema|Atopic Dermatitis \(AD\)
Interventions: OTHER: Blue Cap Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Dyglomera™ on Body Fat and Blood Lipids of Overweight and Obese Adults
Status: COMPLETED
Conditions: Body Fat Disorder
Interventions: DIETARY_SUPPLEMENT: Oral Dyglomera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: S9624 Ifosfamide in Treating Patients With Meningeal Tumors
Status: TERMINATED
Conditions: Chondrosarcoma|Adult Fibrosarcoma|Adult Leiomyosarcoma|Adult Rhabdomyosarcoma|Adult Malignant Meningioma|Adult Brain Malignant Hemangiopericytoma
Interventions: DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine 0.15mg/kg|DRUG: Ketamine 0.3mg/kg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: ruxolitinib cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Periodontal Intervention on Vascular Dysfunction
Status: COMPLETED
Conditions: Chronic Periodontitis|Prehypertension
Interventions: PROCEDURE: One-Stage Full-Mouth Disinfection|PROCEDURE: Periodontal care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Carcinoma|Metastatic Cancer
Interventions: DIAGNOSTIC_TEST: Next Generation Sequencing|DIAGNOSTIC_TEST: Next Generation Sequencing|GENETIC: Biomarker Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Self-pressurised Air-Q With Blocker Versus Baska Mask in Low Risk Female Patients Undergoing Ambulatory Surgery.
Status: UNKNOWN
Conditions: Supraglottic Airway Devices
Interventions: DEVICE: Self-pressurizing Air Q blocker mask measuring airway seal pressure of studied supra-glottic airway devices 10 minutes after insertion|DEVICE: Baska mask measuring airway seal pressure of studied supra-glottic airway devices 10 minutes after insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Culturally Adapted CMAP Plus LTP for Refugee Mothers With History of Self-harm in Pakistan
Status: ACTIVE_NOT_RECRUITING
Conditions: Self-harm|Child Development
Interventions: BEHAVIORAL: CMAP Plus LTP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of (LMWH) in Prevention of Thromboembolic Complication After (TACE) in Hepatocellular Carcinoma.
Status: UNKNOWN
Conditions: HCC
Interventions: DRUG: LMWH|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Distal vs. Forearm Radial Artery Access
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina, Unstable|Angina, Stable|Non STEMI|Non ST Segment Elevation Myocardial Infarction|Acute Coronary Syndrome|Atheroscleroses, Coronary|Atherosclerotic Heart Disease With Ischemic Chest Pain|Chest Pain|Myocardial Infarction|Myocardial Ischemia|ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: PROCEDURE: distal radial artery access in coronary angiography and angioplasty|PROCEDURE: Forearm radial artery access in coronary angiography and angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Cosmetic Product to Preserve Skin Conditions When Using Anti-EGFR Cancer Therapies
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung|Colorectal Neoplasms|Head and Neck Neoplasms
Interventions: DRUG: Application of Onco-Rash cream|DRUG: Application of Onco-Neutre cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Serous Ovarian|Fallopian Tube|Primary Peritoneal Cancer
Interventions: DRUG: Carboplatin and Paclitaxel|DRUG: Nivolumab|PROCEDURE: Cytoreductive surgery|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Loading of Implants in Totally Edentate Upper and Lower Jaw. Trial to Evaluate Survival of the Implants and Bridges, Quality of Prosthetic Work and Patient Satisfaction
Status: COMPLETED
Conditions: Dental Implants
Interventions: PROCEDURE: Immediate loading of implants in totally edentate upper and lower jaw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in PLWH
Status: NOT_YET_RECRUITING
Conditions: Hiv|AIDS|CD4 Deficiency|ART|Treatment Resistant Disorders|Treatment-Sensitive HIV Infection
Interventions: OTHER: differences in CD4 reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Light Therapy for Chronic Insomnia in General Practice
Status: RECRUITING
Conditions: Insomnia Chronic|Sleep Disorder|Circadian Rhythm Disorders
Interventions: DEVICE: Active luminette|DEVICE: Placebo luminette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)
Status: UNKNOWN
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Carvedilol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: ISA 101|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Intervention for Chronic Complex TBI in OEF/OIF/OND Veterans
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury|TBI
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib Monotherapy and Olaparib + Pembrolizumab Combination Therapy for Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With Nab-paclitaxel Plus Cisplatin for Stage Ⅱ-Ⅲ Esophageal Cancer Patients
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: albumin-bound paclitaxel plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teriparatide for Fracture Repair in Humans
Status: WITHDRAWN
Conditions: Osteoporosis, Age-Related|Humeral Fractures
Interventions: DRUG: Teriparatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute Exacerbation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Bronchitis
Interventions: PROCEDURE: respiratory physical therapy manual technique- Autogenic Drainage|DEVICE: respiratory physical therapy technique- IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Postpartum Pelvic Health Through Self-Scar Tissue Massage of Episiotomy and Perineal Scar Tissue A Pilot RCT
Status: RECRUITING
Conditions: Episiotomy; Complications|Scar Tissue|Perineal Tear|Vaginal Tear Resulting From Childbirth
Interventions: PROCEDURE: Pelvic Floor Scar Tissue Self-Scar Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of YYD601 in the Treatment of Esophageal Reflux Disease (ERD)
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: YYD601 40mg|DRUG: Nexium 40mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: AMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Intervention Targeting Daily Adaptive Skills Through Executive Function Training for Adults With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder|High-functioning Autism|Autism
Interventions: BEHAVIORAL: Skills for Adaptive Functioning through Executive training (SAFE; tentative title)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intra-operative Glove-changing During Cesarean Section on Post-op Complications: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Wound Complications
Interventions: PROCEDURE: Glove change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy, Safety, and Tolerability of Laquinimod in Participants With Relapsing Remitting Multiple Sclerosis (RRMS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Laquinimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|TNBC - Triple-Negative Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: PCS6422 and capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SUNPG1623
Status: COMPLETED
Conditions: Active Psoriatic Arthritis
Interventions: DRUG: SUNPG1623 I|DRUG: SUNPG1623 II|DRUG: SUNPG1623 III|DRUG: SUNPG1623 IV|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Mass Balance of [14C] HRS-5965 in Healthy Adult Male Volunteers
Status: NOT_YET_RECRUITING
Conditions: Complement Mediated Primary or Secondary Glomerular Diseases
Interventions: DRUG: [14C] HRS-5965
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of DEC103 in Pain Control Associated to Intrauterine Device (IUD) Insertion
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: DEC103|DRUG: Placebo DEC103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moderate - Severe Degenerative Disc Disease Evaluation of the Lumbar Spine
Status: RECRUITING
Conditions: Lumbar Degenerative Disc Disease
Interventions: DRUG: SB-01 For Injection|DRUG: Sham Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BMS 247550 to Treat Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: BMS-247550|DRUG: Ranitidine|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Postmarketing Surveillance (PMS) Study to Evaluate the Extent to Which Patient Compliance is Influenced by Use of a Variable Titration Regimen at the Start of Treatment of Relapsing Multiple Sclerosis (MS) With Interferon Beta 1a (Rebif®)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Registry Study of 100 Thousand Cases of Pediatric Patients on Reduning Injection（a Chinese Medicine Injection）Used in Hospitals in China
Status: UNKNOWN
Conditions: Upper Respiratory Tract Infection|Acute Tracheobronchitis
Interventions: DRUG: patients under 14 years of age using Reduning injeciton
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Vasculitis on Employment and Income
Status: COMPLETED
Conditions: Vasculitis|Systemic Vasculitis|Behcet's Disease|CNS Vasculitis|Cryoglobulinemic Vasculitis|Eosinophilic Granulomatosis|Temporal Arteritis|Wegener Granulomatosis|Henoch-Schoenlein Purpura|Microscopic Polyangiitis|Polyarteritis Nodosa (PAN)|Takayasu's Arteritis|Urticarial Vasculitis
Interventions: OTHER: online questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Reliability of the Near-infrared Imaging System (VistaCam iX Proxi) in Comparison With Digital Radiographic Findings and ICDAS-II in Detection of Approximal Carious Lesions.
Status: COMPLETED
Conditions: Proximal Dental Caries
Interventions: DEVICE: Vistacam|RADIATION: Bitewing radiograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate How Safe and Well Tolerated RV568 is in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: RV568|DRUG: RV568|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 35 Day Study to Investigate the Effects of GSK1521498 on Bodyweight in Obese Subjects With Over-Eating Behaviours.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: GSK1521498|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Assess the Efficacy and Safety of SC10914 in the Metastatic Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer Metastatic|BRCA 1 Gene Mutation|BRCA 2 Gene Mutation
Interventions: DRUG: SC10914
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Naproxen|DIETARY_SUPPLEMENT: flavocoxid 250 mg|DIETARY_SUPPLEMENT: flavocoxid 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain
Status: NOT_YET_RECRUITING
Conditions: Pain, Cervical|Discogenic Pain
Interventions: DEVICE: Intradiscal Gelified Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Nephrotic Syndrome
Interventions: DIAGNOSTIC_TEST: In-house ELISA, and ELISA kits from "DBA Italy" (Abbexa).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability of BIBR 953 ZW After Dose of BIBR 1048 MS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of SPEAC® System Data on Therapeutic Decisions Related to Convulsive Seizure Patient's Refractory to AEDs
Status: NOT_YET_RECRUITING
Conditions: Epilepsy Intractable
Interventions: DEVICE: SPEAC System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Survivin and Fibulin-3 in Benign and Malignant Respiratory Diseases
Status: COMPLETED
Conditions: Bronchial Neoplasm Benign
Interventions: DIAGNOSTIC_TEST: ELISA assays and Westren blot analysis of survivin and fibulin-3 expression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: Wound Dressing|DEVICE: Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT