pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Site of Puncture in Prelocation Technique of the Internal Jugular Venous Catheterization
Status: NOT_YET_RECRUITING
Conditions: Jugular Veins
Interventions: PROCEDURE: internal jugular vein catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Milk in Life Conditions (MiLC): Bacterial Composition of Human Milk Pumped and Stored in "Real-Life" Conditions
Status: COMPLETED
Conditions: Human Milk Microbiome|Bacterial Growth
Interventions: DEVICE: Sterile pump set-up|DEVICE: Mother's Own pump set-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ball Blankets on Insomnia in Depression in Outpatient Clinics
Status: UNKNOWN
Conditions: Insomnia Due to Mental Disorder
Interventions: DEVICE: Protac Ball BlanketTM (7kg Flexible)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paternally Inherited Phenotypes in Cholestasis
Status: UNKNOWN
Conditions: Cholestasis|Primary Sclerosing Cholangitis|Primary Biliary Cirrhosis
Interventions: OTHER: Questionnaire, semen sample, fasting blood sample|OTHER: Questionnaire|OTHER: Questionnaire, fasting blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nilotinib in Cognitively Impaired Parkinson Disease Patients 001
Status: COMPLETED
Conditions: Parkinson's Disease|Parkinson's Disease Dementia|Diffuse Lewy Body Disease
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of TROP-2 PET/CT for Noninvasive Diagnosis of Solid Tumors
Status: RECRUITING
Conditions: Positron-Emission Tomography|Neoplasms
Interventions: RADIATION: [68Ga]Ga-NOTA-T4 or [18F]AlF-RESCA-T4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic Hyponatremia
Status: WITHDRAWN
Conditions: Hyponatremia
Interventions: DRUG: Tolvaptan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Randomized Trial to Evaluate the Effectiveness of High-Dose Quadrivalent Influenza Vaccine vs. Standard-Dose Quadrivalent Influenza Vaccine in Older Adults
Status: RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: High-Dose Quadrivalent Influenza Vaccine|BIOLOGICAL: Standard-Dose Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Vitamin D and Repletion Strategies
Status: COMPLETED
Conditions: Hypovitaminosis D|Insulin Resistance|Diabetes
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Talk Therapy by Phone to Promote Treatment for Alcohol Problems
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcohol Abuse
Interventions: BEHAVIORAL: CBT by Phone to Promote Treatment|OTHER: Reading the Subject a Pamphlet on Obtaining Alcohol Use Disorder Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fecal Calprotectin Screening and a Gastroenterology Questionnaire for Triaging Children With Chronic Abdominal Pain and/or Diarrhea Referred to a Pediatric Gastroenterology Service
Status: TERMINATED
Conditions: Chronic Abdominal Pain|Chronic Diarrhea
Interventions: OTHER: Fecal calprotectin level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of NX-1607 in Adults With Advanced Malignancies
Status: RECRUITING
Conditions: Ovarian Cancer, Epithelial|Gastric Cancer|GastroEsophageal Junction (GEJ) Cancer|Head and Neck Squamous Cell Carcinoma|Metastatic or Unresectable Melanoma|Non-small Cell Lung Cancer (NSCLC)|Metastatic Castration-resistant Prostate Cancer (mCRPC)|Malignant Pleural Mesothelioma (MPM)|Triple Negative Breast Cancer (TNBC)|Metastatic Urothelial Carcinoma|Cervical Cancer|Diffuse Large B Cell Lymphoma (DLBCL)|Richter Transformation|Microsatellite Stable Colorectal Carcinoma
Interventions: DRUG: NX-1607|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GlitazOne Treatment for Coronavirus HypoxiA, a Safety and Tolerability Open Label With Matching Cohort Pilot Study
Status: COMPLETED
Conditions: Coronavirus Infection|Diabetes
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Education on Breast Milk Perception and Self-Efficacy in the Pregnancy Health Belief Model
Status: COMPLETED
Conditions: Breastfeeding Education
Interventions: BEHAVIORAL: Breastfeeding education based on the Health Belief model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maribavir for Treatment of Resistant or Refractory CMV Infections in Transplant Recipients
Status: COMPLETED
Conditions: Cytomegalovirus (CMV)
Interventions: DRUG: Maribavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
Status: COMPLETED
Conditions: Cardiovascular Disease|Skin Health|Postmenopause
Interventions: DIETARY_SUPPLEMENT: anthocyanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Endothelial Function and Biomarkers in African Americans (AA) With Metabolic Syndrome
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: amlodipine and olmesartan|DRUG: losartan and HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations.
Status: COMPLETED
Conditions: Knee Arthropathy|Hip Arthritis|Fractures, Closed
Interventions: DRUG: Fentanyl|DRUG: Remifentanil|DRUG: Clonidine|DRUG: EMLA Cream|DRUG: Placebo iv|DRUG: Placebo salve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Interventional Open Label Prospective Comparative Observational Study Of Evaluation Of Compliance In The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Of Acute Bacterial Maxillary Sinusitis
Status: COMPLETED
Conditions: Maxillary Sinusitis
Interventions: DRUG: Azithromycin SR|DRUG: Amoxiclav 1000 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscular Dystrophy, Duchenne
Interventions: GENETIC: delandistrogene moxeparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doppler Ultrasound for Prediction of Reversibility of Acute Kidney Injury in Septic ICU Patients
Status: COMPLETED
Conditions: Acute Kidney Injury|Sepsis|Renal Resistive Index
Interventions: DIAGNOSTIC_TEST: color Doppler Ultrasound derived RI and semi-quantitative evaluation of intra-renal vascularization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator
Status: RECRUITING
Conditions: Tetralogy of Fallot|Implantable Defibrillator User|Congenital Heart Disease|Sudden Cardiac Death|Ventricular Arrythmia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of CYP2D6 Genetic Polymorphisms on the Vulnerability to Drug-drug Interactions With Tramadol
Status: UNKNOWN
Conditions: Interaction|Pain
Interventions: DIAGNOSTIC_TEST: Dextrometorphan|GENETIC: Genotyping by single nulcetoide polymorphism.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin for Prevention of Metabolic Side Effects of Olanzapine
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Functional and Biomechanical Outcome by Shear-wave Elastography in the Short to Intermediate Follow-up After Arthroscopic Rotator Cuff Repair
Status: RECRUITING
Conditions: Arthroscopic Rotator Cuff Repair (ARCR)
Interventions: PROCEDURE: Ultrasound (US) examination|PROCEDURE: Clinical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple-Dose Study to Evaluate the Safety and Efficacy of IXT-m200
Status: TERMINATED
Conditions: Methamphetamine-dependence|Methamphetamine Abuse
Interventions: DRUG: IXT-m200|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Status: COMPLETED
Conditions: Acute Low Back Pain
Interventions: DRUG: Naproxen|DRUG: Cyclobenzaprine|DRUG: Oxycodone/ acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Status: COMPLETED
Conditions: DELAYED LABOUR
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Black Raspberry Nectar for the Prevention of Lung Cancer, BE WELL Study
Status: COMPLETED
Conditions: Lung Carcinoma|Tobacco-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DIETARY_SUPPLEMENT: Nutritional Supplementation|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of LCBDE vs ERCP + LC for Choledocholithiasis
Status: COMPLETED
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Psychology and Physiotherapy Approach of Chronic Pain in Patients With Hemophilia
Status: COMPLETED
Conditions: Haemophilia
Interventions: OTHER: Psychology and Physiotherapy group|OTHER: Placebo comparator: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Aromatherapy on the Incidence and Severity of Acute Pain
Status: COMPLETED
Conditions: Venipuncture
Interventions: OTHER: Lavender Aromatherapy|OTHER: Jojoba Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: a Multicentric Randomized Controlled Trial of Self-Expandable Esophageal Radiation Stent
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DEVICE: novel stent|DEVICE: conventional covered stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy Evaluation of Three Dentifrices
Status: COMPLETED
Conditions: Gingival Inflammation and Bleeding|Dental Plaque
Interventions: DRUG: Dentifrices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Doses of GHB04L1 for Pandemic Influenza Prophylaxis in Healthy Adults
Status: COMPLETED
Conditions: Influenza, Avian
Interventions: BIOLOGICAL: GHB04L1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Selective Block of the Suprascapular Nerve
Status: COMPLETED
Conditions: Ligament Injury|Fracture
Interventions: PROCEDURE: LSIB + SSNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canadian Trial of Dietary Carbohydrates in Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Control - high carbohydrate, high glycemic index foods|DRUG: high carbohydrate, low glycemic index foods|DRUG: low carbohydrate, high monounsaturate fat foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Fetal Alcohol Spectrum Disorder (FASD) by the Use of Technology
Status: UNKNOWN
Conditions: Alcoholism|Pregnancy
Interventions: DEVICE: specialized breathalyzer w face recognition technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Health Effects of Ozone Exposure
Status: COMPLETED
Conditions: Pulmonary Function
Interventions: OTHER: 200 ppb ozone group|OTHER: 0 ppb ozone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of BMS-986466 With Adagrasib With or Without Cetuximab in Participants With Kirsten Rat Sarcoma Virus Glycine 12 to Cysteine (KRAS G12C)-Mutant Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: BMS-986466|DRUG: Adagrasib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder
Interventions: DRUG: Quetiapine XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: PROCEDURE: Iodine125-Seeds implantation|DRUG: Gem/nab-P Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Arm Study of Sebacia Microparticles in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: Sebacia microparticle and laser treatment|DEVICE: Vehicle and laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Glycaemic Index and Insulinaemic Index Values of Five Cereal Products
Status: COMPLETED
Conditions: Metabolic Disorder
Interventions: OTHER: Product A: NP-0148|OTHER: Glucose solution|OTHER: Product B: NP-0149|OTHER: Product C: NP-0150|OTHER: Product D: NP-0151|OTHER: Product E: NP-0152
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of ToleroMune Ragweed to Treat Ragweed Allergy in Ragweed Allergic Subjects With Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: ToleroMune Ragweed|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: All Women Comparing Self-expanding ALLEGRA Valve to Any Other Balloon-expandable Valve
Status: NOT_YET_RECRUITING
Conditions: Aortic Stenosis, Severe
Interventions: DEVICE: ALLEGRA TAVI System TF|DEVICE: Ballon-expandable valve system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Inspiratory Muscle Training After Covid-19 (ReCOV)
Status: RECRUITING
Conditions: Covid-19|Respiratory Complication|Post-Acute Covid-19 Syndrome
Interventions: OTHER: Inspiratory muscle training (IMT)|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Rehmannia Glutinosa Leaf Extract in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: OTHER: Rehmannia glutinosa leaf extract|OTHER: Microcrystalline Cellulose (MCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)
Status: COMPLETED
Conditions: Mydriasis|Dilation
Interventions: DRUG: Phentolamine Ophthalmic Solution 0.75%|DRUG: Phentolamine Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Bone-health Effectiveness of Applying Recombinant Factor VIII Fc (rFVIIIFc) to Patients With Hemophilia A (Prototype A)
Status: RECRUITING
Conditions: Severe Hemophilia A Without Inhibitor
Interventions: DIAGNOSTIC_TEST: serum biomarker.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability Study With Oral Single Dose Administration of Ethinylestradiol and Dienogest
Status: COMPLETED
Conditions: Focus: Bioequivalence
Interventions: DRUG: Dienogest-Ethinyl Estradiol (test product)|DRUG: Dienogest-Ethinyl Estradiol (reference product)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of New Biomarkers in the Management and Triage of Patients With Chest Pain and Suspicion of Non ST Elevation Acute Coronary Syndrome.
Status: COMPLETED
Conditions: Coronary Syndrome
Interventions: OTHER: Biological analysis of biomarkers|OTHER: Biological analysis of biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IGF-1 Inhibitor Pasireotide Lar in Combination With the m-TOR Inhibitor Everolimus
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Pasireotide|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Intratumoral Dendritic Cell Immunotherapy in Thermally Ablated Liver Metastases
Status: TERMINATED
Conditions: Liver Cancer
Interventions: BIOLOGICAL: Intratumoral Dendritic Cell Immunotherapy|BIOLOGICAL: autologous dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Gemcitabine With Filgrastim-SD/01 Support in Patients With Advanced Non-Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Filgrastim-SD/01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Weight Loss With SGLT2 Inhibition
Status: COMPLETED
Conditions: Type 2 Diabetes|Overweight|Obesity
Interventions: DRUG: Canagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer
Status: WITHDRAWN
Conditions: Advanced or Metastatic Biliary Tract Cancer
Interventions: DRUG: Varlitinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: fentanyl|DRUG: morphine|PROCEDURE: Transversus abdominis plane block|PROCEDURE: Sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
Status: COMPLETED
Conditions: Symptomatic Decompensated Congestive Heart Failure|Congestive Heart Failure in Acute Coronary Syndrome
Interventions: DRUG: nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Cross Mental Nerve Transfer In Restoration Of Chin &Lip Sensation Post Inferior Alveolar Nerve Injury
Status: UNKNOWN
Conditions: Injury of Mental Nerve of One Side
Interventions: PROCEDURE: Evaluation Of Cross Mental Nerve Transfer In Restoration Of Chin &Lip Sensation Post Inferior Alveolar Nerve Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHNA, Efficacy of Tretinoin Cream on Post-phototherapy Hyperpigmentation
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Tretinoin 0.05% cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
Status: COMPLETED
Conditions: Post-operative Pain|Thoracic Epidural|Thoracotomy Surgery
Interventions: PROCEDURE: thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery|PROCEDURE: thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Endotracheal Tube vs. Aintree Intubating Catheter for Fiberoptic-guided Intubation in Manikin
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: DEVICE: Using long tube|DEVICE: Aintree catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Three, 2 mg Nicotine Chewing Gums (Two Tests and One Reference) in Healthy Adult Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: OTHER: Treatment A: Nicorette 2 mg coated mint gum|OTHER: Treatment B: Nicotinell 2 mg coated mint gum|OTHER: Treatment C: Nicotinell 2 mg coated fruit flavor gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ambroxol Lozenges 20mg in Relieving the Pain of Sore Throat in Adolescent Patients With Acute Viral Pharyngitis
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Ambroxol Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: TGRX-814 Chinese Phase I/II in Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Hematologic Malignancy|Non Hodgkin Lymphoma|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia, Adult|Myelodysplastic Syndromes
Interventions: DRUG: TGRX-814
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Messaging App Reminder on the Compliance of Zero-Time Exercise (ZTEx)
Status: COMPLETED
Conditions: Insomnia, Primary
Interventions: OTHER: Zero Time Exercise training + WhatsApp anti-inertia reminders|OTHER: Zero Time Exercise training alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of a Family-Centered Tai Chi Exercise on Lung Function and Mental Health of Patients After Thoracoscopic Surgery
Status: NOT_YET_RECRUITING
Conditions: Thoracic Neoplasms
Interventions: BEHAVIORAL: Tai Chi Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cohort Study on Patient Outcomes, Effectiveness and Cost-effectiveness of Intervention Programmes for DM/HT Patients
Status: UNKNOWN
Conditions: Hypertension|Diabetes Mellitus|Cardiovascular Diseases|Morbidity, Multiple|Kidney Disease, Chronic|Death
Interventions: PROCEDURE: Different structures and processes of primary care management strategies|PROCEDURE: Multi-disciplinary Risk Factor Assessment and Management Programmes for diabetes (RAMP-DM)|PROCEDURE: Multi-disciplinary Risk Factor Assessment and Management Programmes for hypertension (RAMP-HT)|PROCEDURE: Patient Support Call Centre (PSCC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Minimally Invasive Surgical Strategies for Robot-assisted Supratentorial Large Hematoma
Status: NOT_YET_RECRUITING
Conditions: Hematoma Brain
Interventions: PROCEDURE: Robot-assisted minimally invasive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Nivolumab|PROCEDURE: Irreversible Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiotropium+Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium + olodaterol|DRUG: tiotropium|DRUG: olodaterol|DRUG: tiotropium|DRUG: tiotropium + olodaterol|DEVICE: Respimat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Warm-up Intensity and Blood Flow Restriction
Status: RECRUITING
Conditions: Healthy Men
Interventions: OTHER: Warm-up exercise|OTHER: Warm-up exercise with Blood Flow Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Radiotherapy Related Skin Toxicity: Mepitel® vs. Standard Care in Patients With Locally Advanced Head-and-Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: OTHER: Mepitel® Film|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects
Status: COMPLETED
Conditions: Periodontal Attachment Loss|Periodontal Bone Loss|Periodontal Diseases
Interventions: PROCEDURE: Periodontal Surgery with PRF+ABB|PROCEDURE: Periodontal Surgery with Collagen Membrane +ABB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sputum Labeling Utilizing Synthetic Meso-Tetra (4-Carboxyphenyl) Porphine (TCPP) for Detection of Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DEVICE: CyPath®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: blood-oxygen-level-dependent functional magnetic resonance imaging|PROCEDURE: diffusion tensor imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: functional magnetic resonance imaging|RADIATION: intensity-modulated radiation therapy|RADIATION: radiation therapy treatment planning/simulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Status: RECRUITING
Conditions: Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
Interventions: BIOLOGICAL: Pegozafermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Lymphatic Drainage in the Superior Member in Women in Post-surgery for Breast Cancer
Status: UNKNOWN
Conditions: Lymphedema
Interventions: OTHER: Without upper limb elevation|OTHER: Upper limb elevation to 30º
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal OXygen Therapy in High Risk Patients of Hypoxia Undergoing Diagnostic BRONCHOscopy
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: HFNOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety of Nafamostat Mesylate for Patients With High Risk Bleeding Undergoing Hemodialysis: A Pilot Study
Status: RECRUITING
Conditions: Dialysis; Complications|Bleeding
Interventions: DRUG: Nafamostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Appendiceal Neoplasms|Colorectal Cancer Metastatic
Interventions: DRUG: Modified early post-operative intraperitoneal chemotherapy (mEPIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interactive Digital Health Tools to Improve Patient Safety in Acute Care
Status: COMPLETED
Conditions: Transitions of Care|Patient Portals|General Medicine|Discharge Checklist|Patient-provider Communication|Adverse Event|Readmission
Interventions: BEHAVIORAL: Interactive Digital Health Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analgesic Protocol With Gabapentin Dexmedetomidine For Postoperative Pain Managment
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Dexmedetomidine and Gabapentin|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vestibular Rehabilitation Incorporated With Optokinetic Stimulation in Peripheral Vestibular Dysfunction Patients
Status: RECRUITING
Conditions: Rehabilitation
Interventions: OTHER: Vestibular rehabilitation with optokinetic stimulation|OTHER: Vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants
Status: TERMINATED
Conditions: Infant, Newborn|Respiratory Distress Syndrome|Respiratory Insufficiency
Interventions: DRUG: Early surfactant|DRUG: Standard practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An mHealth Mobile Application Supporting Maintenance of Physical Activity Among Men and Women With High Blood Pressure
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: HeartSteps: A just-in-time intervention for increasing physical activity among sedentary adults.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroid Hormone for the Treatment of Humerus Fractures
Status: UNKNOWN
Conditions: Shoulder Fractures
Interventions: DRUG: 1-84 parathyroid hormone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes (T2D)
Interventions: DRUG: NNC0487-0111 subcutanous|DRUG: Placebo (NNC0487-0111 subcutanous)|DRUG: NNC0487-0111 oral|DRUG: Placebo (NNC0487-0111 oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Manual Therapy and Exercise in Patients With Shoulder Adhesive Capsulitis. A Randomized Clinical Trial.
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: OTHER: Manual therapy|OTHER: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Repeated Doses of DS-8500a on Pharmacokinetics of Rosuvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Drug Pharmacokinetics in Healthy Volunteers
Interventions: DRUG: DS-8500a|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Performance of the COR-VG-001 Conduit in Pediatric Patients for Extracardiac Total Cavopulmonary Connection
Status: COMPLETED
Conditions: Heart Defects, Congenital
Interventions: DEVICE: Vascular Graft, Model COR-VG-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a PIKA Rabies Vaccine（Vero Cell）for Human Use,Freeze-dried
Status: ACTIVE_NOT_RECRUITING
Conditions: Rabies|Prevention
Interventions: BIOLOGICAL: PIKA Rabies Vaccine (Vero Cell) for Human use, Freeze-dried|BIOLOGICAL: Chirorab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine With or Without Aura
Interventions: DRUG: Lasmiditan 50 mg|DRUG: Lasmiditan 100 mg|DRUG: Lasmiditan 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986171 in Healthy People to Assess Safety, to Measure Blood Levels of Drug, and to Find Out What the Drug Does to the Body
Status: COMPLETED
Conditions: Liver Fibrosis/NASH
Interventions: DRUG: BMS-986171|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the GSK2245035 on the Allergen-induced Asthmatic Response
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK2245035 Nasal Spray Solution|DRUG: Placebo Nasal Spray Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Disease Activity and Cardiovascular Risk for Patients With Axial SpondyloArthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RAY1225 in Participants With Type 2 Diabetes
Status: RECRUITING
Conditions: T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: RAY1225|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Annual Study for Serum Collection for Immunogenicity and Safety Evaluation in Healthy Children Receiving Fluzone®
Status: COMPLETED
Conditions: Influenza|Orthomyxoviridae Infections
Interventions: BIOLOGICAL: Influenza Virus Vaccine No Preservative: Pediatric Dose|BIOLOGICAL: Influenza Virus Vaccine No Preservative: Pediatric Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stress Response Pathways in Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: PROCEDURE: Punch Biopsy at a Lesional Site|PROCEDURE: Punch Biopsy at a Non- Lesional site
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipatasertib Plus Non-Taxane Chemotherapy for Advanced or Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Ipatasertib|DRUG: Capecitabine|DRUG: Eribulin|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Computerized Physician Order Entry on Medication Prescription Errors in the Intensive Care Unit: a Controlled Cross-Sectional Trial.
Status: COMPLETED
Conditions: Medication Errors|Patient Safety
Interventions: DEVICE: computerized physician order entry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-2.001: ALT-803 in Patients With Advanced Pancreatic Cancer in Conjunction With Gemcitabine and Nab-Paclitaxel
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: BIOLOGICAL: Gemcitabine|BIOLOGICAL: Nab-paclitaxel|BIOLOGICAL: ALT-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two- Part Proximal Humerus - Conservative vs Operative
Status: RECRUITING
Conditions: Proximal Humerus Fracture|2 Part Fracture
Interventions: PROCEDURE: Open reduction internal stabilisation (ORIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Lansoprazole to Treat Infants With Symptoms of Gastroesophageal Reflux
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Lansoprazole microgranules suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Surufatinib Plus Sintilimab in Patients With Advanced Solid Tumor
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: Surufatinib plus Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Postbiotics in Patients With Macular Atrophy
Status: UNKNOWN
Conditions: Geographic Atrophy|Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: postbiotics (IGENH35.3A)|DIETARY_SUPPLEMENT: vitamins (AREDS formulation and recommended daily dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of INCB050465 in Subjects With Relapsed or Refractory Marginal Zone Lymphoma (CITADEL-204)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the iKnife Distinguish Between Normal and Malignant Endometrial Tissue?
Status: COMPLETED
Conditions: Endometrial Neoplasms|Endometrial Cancer|Endometrial Hyperplasia|Endometrial Diseases
Interventions: DIAGNOSTIC_TEST: iKnife i.e. Rapid Evaporative Ionisation Mass Spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Cognitive Remediation Program for Mood Disorders
Status: UNKNOWN
Conditions: Taking Charge of Cognitive Impairment in Patients With Mood Disorders
Interventions: BEHAVIORAL: Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Cervical Physical Therapy Treatment in Patients With Somatic Tinnitus
Status: WITHDRAWN
Conditions: Tinnitus, Subjective
Interventions: OTHER: Cervical physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Palm Olein Intake on Lipid Profile and Fat Deposition
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Palm olein|DIETARY_SUPPLEMENT: Interesterified palm olein|DIETARY_SUPPLEMENT: soybean oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of DLBS1033 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DLBS1033|DRUG: placebo tablet of DLBS1033
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Bronchiectasis in Infants With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: DRUG: Azithromycin|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer
Status: NOT_YET_RECRUITING
Conditions: Barrett's Esophagus|Esophageal Adenocarcinoma
Interventions: PROCEDURE: Endoscopic brush cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: H-PACE Program for the Improvement of Lifestyle Behaviors Among Children
Status: ENROLLING_BY_INVITATION
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: H-PACE Behavioral Intervention|OTHER: Accelerometer|OTHER: Questionnaire Administration|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Status: COMPLETED
Conditions: Fluid Overload
Interventions: DEVICE: HUNTLEIGH FLOWTRON ACS900
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION