pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: 2940nm Er:YAG Laser and 1927nm Thulium Laser in Improving Atrophic Acne Scars
Status: UNKNOWN
Conditions: Atrophic Acne Scar
Interventions: DEVICE: 1927nm thulium laser|DEVICE: 2940nm Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Early Bactericidal Activity, Safety and Tolerability of Nebulised RESP301 in Adults With Tuberculosis
Status: RECRUITING
Conditions: Rifampicin Susceptible Pulmonary Tuberculosis
Interventions: DRUG: RESP301|DRUG: HRZE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Bronchoscopy and Real- Time Ultrasound Guided Percutaneous Tracheostomy
Status: COMPLETED
Conditions: Tracheostomy Complications
Interventions: DEVICE: Ultrasound guided percutaneous tracheostomy|DEVICE: Bronchoscopy guided percutaneous tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota and Immune microEnvironment in Pouchitis
Status: UNKNOWN
Conditions: Pouchitis|Ulcerative Colitis|Ileal Pouch
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei DG|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Pharmacokinetics, Safety and Efficacy of Albiglutide in Pediatric Subjects With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Albiglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Balloon Catheter Versus Dinoprostone Vaginal Insert for Cervical Ripening.
Status: COMPLETED
Conditions: Cervical Ripening|Labor Induction
Interventions: DEVICE: Double balloon catheter|DRUG: Dinoprostone 10 mg controlled-release vaginal insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JUVÉDERM® VOLUMA® With Lidocaine for Correction of Temple Hollowing in Chinese Population
Status: COMPLETED
Conditions: Temple Hollowing
Interventions: DEVICE: JUVÉDERM® VOLUMA® with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Treatment of Male Partners of Women With BV
Status: COMPLETED
Conditions: Recurrent Bacterial Vaginosis
Interventions: DRUG: Metronidazole (male partner)|OTHER: Placeob (male partner)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness, DOMS
Interventions: DRUG: Comboprofen|DRUG: Placebo|DRUG: Ibuprofen|DRUG: Magnesium|DRUG: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the EarPopper Device in Children With Recurrent Otitis Media
Status: WITHDRAWN
Conditions: Recurrent Acute Otitis Media|Acute Otitis Media
Interventions: DEVICE: EarPopper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study on the Effect of a XOS95 on the Human Gut Microbiome
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Xylooligosaccacharide|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Irritation and Sensitization Study of HP-5000 Topical System
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: HP-5000 Topical Patch|DRUG: HP-5000 Placebo Patch|DRUG: Saline Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Non-inferiority With Participants Diagnosed With Primary Knee OA (GLACIAL)
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DRUG: Glucosamine and chondroitin sulfate combination (Eurofarma)|DRUG: Glucosamine and chondroitin sulfate combination (Zodic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars
Status: COMPLETED
Conditions: Hypertrophic or Keloid Scars
Interventions: DRUG: Silicone gel Kelo-cort™;|DRUG: Onion extract gel Contractubex™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Urothelial Carcinoma In Situ|Recurrent Bladder Urothelial Carcinoma|Stage 0a Bladder Cancer AJCC v8|Stage 0is Bladder Cancer AJCC v8|Stage I Bladder Cancer AJCC v8|Superficial Bladder Urothelial Carcinoma
Interventions: DEVICE: Acupuncture Therapy|BIOLOGICAL: BCG Solution|OTHER: Best Practice|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Beans Compared to Beef on Satiety in Older Adults
Status: COMPLETED
Conditions: Older Adults
Interventions: OTHER: Canned black beans, drained and rinsed|OTHER: Canned red kidney beans, drained and rinsed|OTHER: Extra-lean ground beef
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart Failure
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Failure, Congestive
Interventions: DEVICE: Pacemaker Medtronic EnRhythm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Surgery in Treating Children With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Chronic Myelomonocytic Leukemia|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts
Interventions: OTHER: antitumor drug screening assay|DRUG: chemotherapy|BIOLOGICAL: biological therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Effect of IAP0971 in Patients With Advanced Malignant Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Neoplasm|Advanced or Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: IAP0971
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Long-term Effects Secondary to Cancer Therapy in Children|Ototoxicity
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: methotrexate|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|PROCEDURE: cognitive assessment|PROCEDURE: magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine and Oxaliplatin Followed By Radiation Therapy, Fluorouracil, and Oxaliplatin in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide to Aid Establishment of Breastfeeding:a Randomised Controlled Trial
Status: COMPLETED
Conditions: Breastfeeding
Interventions: DRUG: Metoclopramide (Maxolon)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans
Status: RECRUITING
Conditions: Cannabis
Interventions: DRUG: THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FLT PET/CT for Staging, Target Definition and Assessment of Response to Therapy in Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: 3'-deoxy-3'-(18) F-fluorothymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tuberculosis (TB) Immunotherapy Phase 2 Study
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: V7|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Brain Damage Resulting From Carotid Endarterectomy With Xenon Anesthesia
Status: COMPLETED
Conditions: Carotid Endarterectomy
Interventions: DRUG: Anesthesia with Xenon|DRUG: Standard anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stopping TNF Alpha Inhibitors in Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Infliximab|DRUG: Adalimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avazzia HVPC Bio-Electrical Stimulation Technology (BEST™) Microcurrent CTS RCT
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: BEST™ HVPC microcurrent electrical stimulation PRO-SPORT Ultra® Device|DEVICE: Sham PRO-SPORT Ultra® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Tetanus Toxoid Vaccine|DRUG: Indinavir sulfate|DRUG: Lamivudine/Zidovudine|DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Efavirenz|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Continuous Double Ovarian Stimulation.
Status: RECRUITING
Conditions: Fertility Issues
Interventions: DRUG: Corifollitropin Alfa|DRUG: Follitropin Alfa|DRUG: Follitropin Alfa Biosimilar|DRUG: Urinary Human follicle stimulating hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Erlotinib in Treating Patients With Metastatic or Recurrent Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Erlotinib|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Physiological Effects of Acute and Ramp Simulated Altitude Exposure During Simulated Flight Tasks
Status: NOT_YET_RECRUITING
Conditions: Altitude Hypoxia
Interventions: OTHER: Hypoxic breathing conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: CC-122|DRUG: CC-223|DRUG: Rituximab|DRUG: CC-122|DRUG: CC-292|DRUG: Rituximab|DRUG: CC-223|DRUG: CC-292|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: US-guided breast biopsy|OTHER: Ultrasound-guided breast biopsy training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-Simufilam Following a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Absorption|Metabolism|Excretion
Interventions: DRUG: Simufilam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Plaque Modification And Impact On Microcirculatory Territory After Drug-Coated Balloon Percutaneous Coronary Intervention (PLAMI).
Status: RECRUITING
Conditions: Coronary Artery Disease|Drug Coated-balloon|Intravascular Ultrasound|Plaque Modification|Percutaneous Coronary Intervention|Microvascular Coronary Artery Disease
Interventions: DEVICE: Drug coated-balloon percutaneous coronary intervention.|DEVICE: Angiography-derived coronary physiology (IMRangio)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immunogenicity and Safety of 60mcg/30mcg Recombinant Hepatitis B Vaccines in People Who Failed to Respond to Routine Administration of Hepatitis B Vaccines
Status: COMPLETED
Conditions: Hepatitis b
Interventions: BIOLOGICAL: 60mcg/1.0ml recombinant hepatitis B vaccine|BIOLOGICAL: 30mcg/1.0ml recombinant hepatitis B vaccine|BIOLOGICAL: 10mcg/1.0ml recombinant hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MIP Versus PCNL for Kidney Stone Disease
Status: UNKNOWN
Conditions: Kidney Stone
Interventions: PROCEDURE: Standard Percutaneous Nephrolithotomy (sPCNL)|PROCEDURE: Minimally Invasive Percutaneous Nephrolithotomy (MIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug-Eluting Balloon Angioplasty Versus Bypass Surgery as First-Line Strategies in Infrageniculate Arterial Disease for Critical Limb Ischemia in Type 2 Diabetic Pacients: a Randomised Controlled Clinical Trial
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: Vein bypass surgery first strategy|PROCEDURE: Endovascular treatment first (drug coated balloon angioplasty) strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Patient Cohort of the National Center for Precision Medicine in Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|High-risk Myelodysplastic Syndrome|Secondary Myelofibrosis in Myeloproliferative Disease|Myeloproliferative Neoplasm, Unclassifiable
Interventions: OTHER: Biobanking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Equity in Transplant Evaluation and Living Donor Kidney Transplantation
Status: COMPLETED
Conditions: End-stage Kidney Disease
Interventions: OTHER: Talking About Living Kidney Donation|OTHER: Kidney Transplant Fast Track
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cladribine in Combination With GAP in Patients With Refractory/Relapsed Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Cladribine|DRUG: G-CSF|DRUG: Cytarabine|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Pembrolizumab(Pbr)/Nab-Paclitaxel Followed by Pbr/Epirubicin/Cyclophosphamide in TNBC
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: DRUG: Pembrolizumab|DRUG: nab-paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBS Digital Behavioral Treatment
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: Arm 1 - Active behavioral Treatment Arm (Regulora; Gut-Directed Hypnotherapy Software as a Medical Device - SaMD)|DEVICE: Arm 2 - Active Comparator behavioral treatment arm (MR-1; Muscle Relaxation, Software as a Medical Device - SaMD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Gabapentin|DRUG: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pain Management in Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Patients Who Are About to be Treated With Adalimumab
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biodegradable Stents in the Management of Stenoses of the Large Airways
Status: SUSPENDED
Conditions: Tracheal Stenosis
Interventions: DEVICE: SX-ELLA Stent DV Tracheal (DV Stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
Status: RECRUITING
Conditions: Premature Birth
Interventions: PROCEDURE: Prophylactic Delivery Room Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With XLH
Status: COMPLETED
Conditions: X-linked Hypophosphatemia (XLH)
Interventions: DRUG: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Definitive Radiation for High-Risk Spine Metastases
Status: RECRUITING
Conditions: Metastatic Cancer|Metastatic Lung Cancer|Metastatic Breast Cancer|Metastatic Tumor|Metastatic Tumor of Bone|Metastatic Tumor to the Spine|Spine Metastases|Metastasis
Interventions: RADIATION: SBRT to the spine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Pseudomonas Aeruginosa|Pseudomonas|Lung Infection|Lung Infection Pseudomonal
Interventions: BIOLOGICAL: AP-PA02|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Status: RECRUITING
Conditions: Neuroblastoma|Sarcoma|Osteosarcoma
Interventions: DRUG: B7-H3CART Dose (Intravenous)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Evaluation of Emergent Immobilization in External Rotation in the Management of Acute Anterior Dislocations of the Shoulder
Status: TERMINATED
Conditions: Primary Anterior Shoulder Dislocation
Interventions: DEVICE: Sling|DEVICE: External Rotation Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: methotrexate|DRUG: vinblastine sulfate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Augmentation Study of A Computerized Treatment for Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: CBM With Active Fear Reactivation|BEHAVIORAL: CBM With Inert Fear Reactivation|BEHAVIORAL: Inert CBM With Inert Fear Reactivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Efficacy and Safety of GSK2402968 in Subjects With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DRUG: GSK2402968 6mg/kg/week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neural Slump Mobilization in Addition to Conventional Physical Therapy in Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Neural slump mobilization|PROCEDURE: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma
Status: COMPLETED
Conditions: Melanoma Stage Iii|Melanoma Stage Iv|Melanoma|Melanoma (Skin)|Cutaneous Melanoma
Interventions: DRUG: Denosumab|DRUG: Pembrolizumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Middle Meningeal Artery (MMA) Embolization Compared to Traditional Surgical Strategies to Treat Chronic Subdural Hematomas (cSDH)
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: Middle Meningeal Artery procedure|PROCEDURE: Traditional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nitric Oxide Metabolites for Predicting Embryo Quality in In-Vitro Fertilization (IVF)
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: Transfer of embryos on day 3 or day 5 after fertilization.|PROCEDURE: Day 5 transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Coronary Slow Flow or No-Reflow During PPCI in Patients With Acute STEMI
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction|Primary Percutaneous Coronary Intervention
Interventions: DRUG: Nitroprusside Sodium|DRUG: Tirofiban Hydrochloride|DRUG: Heparinized saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis.
Status: COMPLETED
Conditions: Chronic Periodontitis Complex
Interventions: DRUG: Placebo Oral Tablet|DRUG: Amoxicillin 500 Mg|DRUG: Lactobacillus reuteri Oral Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Magnetic Resonance Imaging (MRI) With Gadavist in Children
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadobutrol (Gadavist, Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Surface Coverage of Two Types of DES in Diabetes Mellitus and Non- Diabetes Mellitus
Status: UNKNOWN
Conditions: Coronary Artery Disease|Diabetes Mellitus
Interventions: DEVICE: Device: Polymer-based sirolimus-eluting stent(Cypher stent ) and Polymer-free paclitaxel-eluting stent (YinYi stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates
Status: COMPLETED
Conditions: Meditation|Pain|Mindfulness|Affect|Emotion Regulation
Interventions: BEHAVIORAL: Mindfulness-enhanced positive affect induction|BEHAVIORAL: Breathing Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty
Status: RECRUITING
Conditions: To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients
Interventions: DIAGNOSTIC_TEST: Evaluation of Synovial IL-6 in diabetic patients with gonarthrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Efficacy and Safety of HCQ and Antibiotics Administrated to Patients COVID19(+)
Status: WITHDRAWN
Conditions: Patients With COVID19
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: eBehandling - Health and Work for Patients in Specialist Mental Health Care
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Transdiagnostic, work-focused Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser for Oral Mucositis in Pediatric Onco-hematology
Status: COMPLETED
Conditions: Stomatitis
Interventions: DEVICE: Laser therapy|DEVICE: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Finger Pupiling On Pain And Physiological Parameters in İnfants
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: THE EFFECT OF FINGER PUPPET MANIPULATION ON PAİN AND PHYSİOLOGıCAL PARAMETERS DURING URINARY CULTURE WITH URINARY CATHETERIZATION IN INFANTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: OTHER: RADITIONAL MODERATE INTENSITY TRAINING|OTHER: HIGH INTENSITY INTERVAL TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: Computational Model - Real-time Support Vector Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC)
Status: RECRUITING
Conditions: SCLC,Extensive Stage
Interventions: DRUG: Pembrolizumab/Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Enhanced Angiogenic Cell Therapy - Acute Myocardial Infarction Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Wall Myocardial Infarction
Interventions: BIOLOGICAL: Plasma-Lyte A and 25% Autologous Plasma|BIOLOGICAL: Autologous EPCs|BIOLOGICAL: Autologous EPCs Transfected with human eNOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of VOICES as Implemented by STD & HIV Prevention Agencies in the US and PR
Status: COMPLETED
Conditions: Sexually Transmitted Diseases
Interventions: BEHAVIORAL: VOICES/VOCES|BIOLOGICAL: Standard STD clinic services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The ICU-recover Box, Using Smart Technology for Monitoring Health Status After ICU Admission
Status: COMPLETED
Conditions: Critically Ill|ICU Survivor|User Experience
Interventions: DEVICE: Withings ScanWatch|DEVICE: Withings BPM Connect|DEVICE: Withings Body
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Breadth of Donor Options for People With Inherited Diseases Requiring Allogeneic Hematopoietic Stem Cell Transplant in the Era of Alternative Donor Transplants Using Post-Transplantation Cyclophosphamide
Status: COMPLETED
Conditions: Primary T-cell Immunodeficiency Disorders|Common Variable Immunodeficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Distal Adductor Canal Block With Periarticular Local Anesthetic Infiltration Versus Continuous Distal Adductor Canal Block Alone for Analgesia After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Degenerative Osteoarthritis
Interventions: PROCEDURE: Distal adductor canal block|PROCEDURE: Distal adductor canal block and Periarticular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Prewarming on Perioperative Body Core Temperature and the Outcomes of Cytoreductive- and Major Open Abdominal Surgery: A Randomised Trial
Status: UNKNOWN
Conditions: Hypothermia
Interventions: OTHER: Prewarming|DEVICE: Microdialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Tegafur/Uracil (UFUR®) for Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: tegafur/uracil (UFUR®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy
Interventions: DRUG: Ozarelix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Comprehensive Chromosomal Testing of Trophectoderm Biopsies of Blastocysts in In Vitro Fertilization
Status: RECRUITING
Conditions: Infertility
Interventions: PROCEDURE: Comprehensive chromosomal Testing of Trophectoderm biopsies of Blastocysts (CTTEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study
Status: COMPLETED
Conditions: Obesity|Obesity, Abdominal|Obesity, Visceral|Female
Interventions: DIETARY_SUPPLEMENT: Alpha lipoic acid (plus full hospitalization)|DIETARY_SUPPLEMENT: Placebo (full hospitalization: dietary monitoring with an adapted physical activity program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Sublimated mare milk|DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetic (PK) Study of GSK2982772 in Healthy Subjects
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DRUG: GSK2982772 capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal Surgery
Status: COMPLETED
Conditions: Major Abdominal Surgery
Interventions: DRUG: Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine|DRUG: Goal-directed hemodynamic therapy|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Shifting Away From Pain: a Neurocognitive Approach in Treatment of Whiplash
Status: COMPLETED
Conditions: Whiplash Injuries
Interventions: BEHAVIORAL: Modern pain neuroscience approach|BEHAVIORAL: Usual care physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NK DLI in Patients After Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Myelodysplastic Syndromes|Lymphoma|Neuroblastoma|Rhabdomyosarcoma
Interventions: BIOLOGICAL: CD3-depleted/CD56+ selected natural killer cells collected from apheresis products
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Block to Treat Shoulder Pain After Laparoscopic Surgery
Status: UNKNOWN
Conditions: Nerve Block
Interventions: DRUG: Lidocaine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saline With Alcohol in TransUrethral Resection aNd Photoselective Vaporisation of the Prostate
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy
Interventions: DRUG: Saline Irrigation with Ethanol|PROCEDURE: transurethral resection of the prostate|PROCEDURE: photoselective vaporisation of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temozolomide|DRUG: Disulfiram|DRUG: Copper
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different β -Blockers in STEMI and Primary PCI
Status: NOT_YET_RECRUITING
Conditions: Primary PCI
Interventions: DRUG: β -Blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Efficacy and Pharmacokinetics of GSK1278863 in Japanese Hemodialysis-Dependent Subjects With Anemia Associated With Chronic Kidney Disease
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Standardization of D. Glomerata, L. Perenne, S. Cereale and O. Europaea Pollen Extracts
Status: COMPLETED
Conditions: Sensitization to Allergens
Interventions: BIOLOGICAL: Skin Prick Test|BIOLOGICAL: Skin Prick Test - Atopic Subjects|BIOLOGICAL: Skin Prick Test - No Atopic Subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: L19-IL2 - Ph I|DRUG: L19-IL2 at RD - Ph II|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Tuvusertib (M1774)|DRUG: Niraparib|DRUG: Lartesertib (M4076)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Role of Microdialysis for the Comparison of Topical Products
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Reference, Patch location thigh, batch 1|DEVICE: Test, Patch location thigh, batch 2|DRUG: Reference, Patch location abdomen, batch 1|DEVICE: Test, Patch location abdomen, batch 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Parent Child Program to Prevent Adolescent Pregnancy
Status: COMPLETED
Conditions: Adolescent Pregnancy|Sexually Transmitted Diseases|Parental|Communication|Sexuality
Interventions: BEHAVIORAL: Let's Talk About Sex|BEHAVIORAL: Websites; preventing teen pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Erlotinib Versus Gemcitabine/Carboplatin in Chemo-naive Stage IIIB/IV Non-Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Exon 19 or 21 Mutation
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: gemcitabine/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Trial of Intravenous Pulse Versus Sequential Steroid Therapy for Patients With Graves' Orbitopathy
Status: UNKNOWN
Conditions: Graves' Ophthalmopathy
Interventions: DRUG: methylprednisolone, prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Plant Stanol|DIETARY_SUPPLEMENT: Plant Sterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: JZP-110
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Sleep Disorder|Sleep Disturbance
Interventions: BEHAVIORAL: LOCK Sleep Program|OTHER: No intervention (control period/baseline data collection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib Plus Prednisone for Initial Therapy of Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: bortezomib|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Validity of A Novel Computer Based Battery of Assessments in the Elderly
Status: COMPLETED
Conditions: Computerized Assessment Feasibility and Validity
Interventions: OTHER: HHT-G|OTHER: HHT-D|OTHER: Geriatric Depression Scale (DGS)|OTHER: MMSE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Phosphodiesterase-3 Inhibitor Cilostazol as an Adjunctive to Antidepressants in Patients With Major Depressive Disorder.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Cilostazol 50 MG Oral Tablet|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of LO2A Eye Drops in Patients With Conjunctivochalasis
Status: COMPLETED
Conditions: Conjunctivochalasis
Interventions: DRUG: LO2A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-enhanced Delivery of Chemotherapy to Patients With Liver Metastasis From Breast- and Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Breast Neoplasms
Interventions: DRUG: SonoVue|PROCEDURE: Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Fibrotic Effects of Losartan In Nash Evaluation Study
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Betaine Supplementation on Strength and Muscle Creatine Content
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: creatine|DIETARY_SUPPLEMENT: betaine|DIETARY_SUPPLEMENT: dextrose|DIETARY_SUPPLEMENT: creatine plus betaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment:Pilot Study
Status: UNKNOWN
Conditions: Apathy|Mild Cognitive Impairment
Interventions: DEVICE: Neurostar repetitive transcranial magnetic stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biodistribution&Pharmacokinetic of Position Emission Tomography(PET) Radiopharmaceutical 18F C SNAT4
Status: RECRUITING
Conditions: Cancer|Lung Cancer
Interventions: DRUG: 18F-C-SNAT4|PROCEDURE: Positron emission tomography (PET)/Computed tomography (CT) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Treatment With NeoRecormon (Epoetin Beta) in Patients With Chronic Renal Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin beta [NeoRecormon]|DRUG: epoetin beta [NeoRecormon]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT