pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Cardiopulmonary Diseases by Ultrasound
Status: COMPLETED
Conditions: Dyspnea|Acute Decompensated Heart Failure
Interventions: DEVICE: Recording Doppler ultrasound signals noninvasively
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Haloperidol and Dexamethasone Towards Postoperative Nausea and Pain in Adult After Laparoscopy
Status: COMPLETED
Conditions: Laparoscopy|Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone injection|DRUG: Haloperidol Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Exploratory Biomarker Study of ABT-126 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABT-126|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BE Study Between a Capsule and a Sachet Formulation of D961H by Pharmacodynamics in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Gastric Ulcer|Duodenal Ulcer|Anastomotic Ulcer|Reflux Esophagitis|Etc.
Interventions: DRUG: D961H sachet 20 mg|DRUG: D961H HPMC capsule 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autologous Serum Eye Drops With Contact Lenses for Corneal Epithelial Defects
Status: COMPLETED
Conditions: Corneal Diseases
Interventions: DRUG: Continuous use of topical autologous serum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Assessment in Ovarian Cancer (TRSGO-SLN-OO5)
Status: UNKNOWN
Conditions: Ovarian Cancer|Sentinel Lymph Node
Interventions: DIAGNOSTIC_TEST: Sentinel lymph node detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Ivabradine in Patient With Both Persistent Atrial Fibrillation and Heart Failure With Reduce Ejection Fraction
Status: UNKNOWN
Conditions: Atrial Fibrillation|Ivabradine|Heart Failure
Interventions: DRUG: Ivabradine 5 mg [Corlanor]|DRUG: Digoxin 0.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Remifentanil With a Combination of Remimazolam and Dexmedetomidine for Awake Tracheal Intubation
Status: NOT_YET_RECRUITING
Conditions: Difficult or Failed Intubation|Sedative Adverse Reaction
Interventions: DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Biphasic Insulin Aspart (30, 50 and 70) and Insulin Aspart in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 50|DRUG: biphasic insulin aspart 70|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Time-restricted Eating, Window Timing, Type 2 Diabetes Status and Sex on Glycemic Control
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity|Prediabetic State|Hyperglycemia
Interventions: BEHAVIORAL: Early (7:00 - 16:00) TRE|BEHAVIORAL: Mid (9:30 - 18:30) TRE|BEHAVIORAL: Late (12:00 - 21:00) TRE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Impairment Study
Status: COMPLETED
Conditions: Liver Disease
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closing the Loop in Adults With Type 1 Diabetes and HbA1C<7.5% Under Free Living Conditions
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Florence D2A or similar closed loop glucose control system|DEVICE: CSII with CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Healthy Children Aged 15 Months to 17 Years
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BIOLOGICAL: 13 valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Behavioral Economics to Enhance Appointment Reminders and Reduce Missed Visits
Status: COMPLETED
Conditions: Appointment Reminders
Interventions: BEHAVIORAL: Social Norms + Behavioral Instructions|BEHAVIORAL: Caring + Consequences for Others + Behavioral Instructions|BEHAVIORAL: Caring + Consequences for Self + Behavioral Instructions|BEHAVIORAL: Caring + Consequences for Others + Consequences for Self + Social Norms + Behavioral Instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
Status: COMPLETED
Conditions: Parkinson Disease|Dyskinesia, Drug-Induced|Levodopa
Interventions: DRUG: AFQ056
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension in Preeclamptic Patients
Status: RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Alpha-Agonist|DRUG: α-adrenergic receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Relative Bio-availability Study of Dolutegravir and Lamivudine Fixed Dose Combinations
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Dolutegravir 50 mg tablet|DRUG: Lamivudine 300 mg tablet|DRUG: Dolutegravir/Lamivudine 50 mg/300 mg Tablet (Product Code AA)|DRUG: Dolutegravir/Lamivudine 50 mg/300 mg Tablet (Product Code AB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of LY3372689 on the Brain in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3372689|DIAGNOSTIC_TEST: [18F]LSN3316612
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Olaparib|DRUG: Cetuximab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetic and Safety of NVP-2102 and NVP-2102-R in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: NVP-2102|DRUG: NVP-2102-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Thoracic Mobility Versus Lumbopelvic Stabilization Exercises On Patients With Chronic Ankle Instability
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: PROCEDURE: Thoracic Mobility Rehabilitation|PROCEDURE: Lumbopelvic Stability Rehabilitation|PROCEDURE: Ankle Strengthening Home Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Electrical Pudendal Nerve Stimulation for Patients With Post Prostatectomy Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Electrical pudendal nerve stimulation|DEVICE: PFM training|DEVICE: Transanal ES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Insulins Aspart and Lispro in Insulin Pumps
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin Aspart|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Transvaginal Hybrid Anterior Resection: a Prospective Data Collection
Status: COMPLETED
Conditions: Sigmoid Diverticulitis (Hinchey I and II)|Sigmoid Diverticulosis With Two or More Attacks of Diverticulitis
Interventions: PROCEDURE: Laparoscopic transvaginal hybrid anterior resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial of Preoperative Combined Modality Therapy for Esophageal Carcinoma: Cisplatin-Irinotecan Followed by Radiation Therapy With Concurrent Cisplatin and Irinotecan.
Status: COMPLETED
Conditions: Esophageal Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Irinotecan|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Comparison of the Use of FloShield Air System ® Versus the Referenced Technic (Water + Povidone-Iodine Solution) During Gynecologic Endoscopic Surgery to Evaluate the Operative Lens Vision Quality
Status: COMPLETED
Conditions: The Performance Evaluations of the FloShield Defogging and Cleaning System
Interventions: DEVICE: FloShield Defogging and Cleaning System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Paliperidone Palmitate in Patients With Schizophrenia Previously Unsuccessfully Treated by Oral Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone Palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chlamydia Infection Comparing WC2031 Tablets With Vibramycin
Status: COMPLETED
Conditions: Urogential Chlamydia Trachomatis Infection
Interventions: DRUG: Doxycyline Hyclate tablet|DRUG: Vibramycin (doxycyline hyclate) capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin in Treatment of Diabetes Mellitus With Pregnancy
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Basal insulin analogue|DRUG: rapid acting insulin|DRUG: Neutral Protamine Hagedorn|DRUG: regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivor|Dysphagia|Fibrosis|Head and Neck Carcinoma
Interventions: PROCEDURE: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Window of Opportunity Study of KTN3379 in Surgically Resectable Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: KTN3379
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of T-wave™ Coronary Lithotripsy Catheter System
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Calcified Coronary Artery Stenosis
Interventions: DEVICE: T-wave coronary lithotripsy catheter system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prophylactic Antiemetic Dexamethasone on Plasma Cortisol Levels
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Saline|DRUG: Dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Maintenance After Autologous Hematopoietic Stem Cell Transplantation for Relapsed, Refractory or High-risk Lymphoma
Status: UNKNOWN
Conditions: Experimental Tumor
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Superficial Keratotomy on Reducing Postoperative Pain Fallowing Conjuctival Flap
Status: COMPLETED
Conditions: Reduced Corneal Sensation
Interventions: PROCEDURE: corneal neurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Status: COMPLETED
Conditions: Tuberous Sclerosis|Angiofibroma|Hypomelanotic Macule|Plaque
Interventions: DRUG: NPC-12G gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Fludarabine|DRUG: Rituximab|DRUG: Thymoglobulin|PROCEDURE: Stem Cell Transplantation|DRUG: Bendamustine|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial on the Efficacy of Tenofovir Disoproxil Fumarate (TDF)-Switch Therapy in Chronic Hepatitis B Patients With Incomplete Response to Entecavir
Status: COMPLETED
Conditions: Chronic Heptitis B
Interventions: DRUG: tenofovir disoproxil fumarate|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Open-Label Study of High-Dose Cytarabine and Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Refractory or Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: clofarabine|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of FS 4 IU VH S/D (Fibrin Sealant With 4IU/mL Thrombin, Vapor Heated, Solvent/Detergent Treated) to Adhere Split Thickness Skin Grafts and Improve Wound Healing in Burn Patients
Status: COMPLETED
Conditions: Deep Partial or Full Thickness Wounds
Interventions: BIOLOGICAL: Fibrin Sealant, ARTISS 4IU/ml VH SD|OTHER: Staples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oncoxin in Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DIETARY_SUPPLEMENT: Oncoxin|OTHER: Supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Strategy to Decolonize Methicillin-resistant Staphylococcus Aureus (MRSA) in the Outpatient Setting
Status: COMPLETED
Conditions: Methicillin-resistant Staphylococcus Aureus
Interventions: DRUG: pharmacological decolonization treatment|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound
Status: ACTIVE_NOT_RECRUITING
Conditions: Carotid Atherosclerosis
Interventions: DIAGNOSTIC_TEST: Perflutren
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Elevated Arterial Pulmonary Pressure With Inhaled Iloprost
Status: WITHDRAWN
Conditions: Persistent Pulmonary Hypertension|Respiratory Distress Syndrome
Interventions: DRUG: iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Outcomes of Low Testosterone
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypogonadism
Interventions: DRUG: Acyline|DRUG: Placebo Gel|DRUG: Placebo Tablet|DRUG: Testosterone Gel|DRUG: Arimidex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of DKF-313 in Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: DKF-313|DRUG: Dutasteride|DRUG: Tadalafil|DRUG: DKF-313 placebo|DRUG: Dutasteride placebo|DRUG: Tadalafil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of HS-10374 for Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: HS-10374 tablets 1mg|DRUG: HS-10374 tablets 5mg|DRUG: HS-10374-matched placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Efficacy and Safety of BioChaperone Combo and Humalog Mix 25 in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: BioChaperone® Combo|DRUG: Humalog® Mix25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epinastine and Pseudoephedrine Fixed Combination Compared to Separate Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epinastine|DRUG: Pseudoephedrine|DRUG: Epinastine + Pseudoephedrine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atacicept in Subjects With IgA Nephropathy
Status: RECRUITING
Conditions: IgA Nephropathy|Berger Disease
Interventions: BIOLOGICAL: Atacicept|OTHER: Placebo to match Atacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antiepileptic Drug in Generalised Convulsive Status Epilepticus
Status: COMPLETED
Conditions: Status; Epilepticus, Tonic-clonic
Interventions: DRUG: Levetiracetam/Clonazepam|DRUG: Clonazepam/Placebo levetiracetam IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)|Avoidant Personality Disorder|Dependent Personality Disorder|Obsessive Compulsive Personality Disorder
Interventions: BEHAVIORAL: ImRS|BEHAVIORAL: SFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CriPec® Docetaxel Given to Patients With Solid Tumours
Status: COMPLETED
Conditions: Cancer|Metastatic Cancer|Solid Tumors
Interventions: DRUG: CriPec® docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Adding Linagliptin to Control Glycemic Variability and HbA1c in Peritoneal Dialysis Patients With Type 2 Diabetes(PDPD) With Premixed Insulin Therapy
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Peritoneal Dialysis
Interventions: DRUG: Linagliptin|DRUG: Humalog Mix 75/25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web-Based Education in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Educational Problems
Interventions: OTHER: Web-Based Education|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of a α1A Adrenoceptor Selective Antagonist Silodosin to Treat Severe Benign Prostatic Hyperplasia(BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Silodosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Quinine Sulfate as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia ( DEAL-COVID19 )
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Standard of Care + Quinine Sulfate|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: STRatIfication of Vulvar Squamous Cell Carcinoma by HPV and p53 Status to Guide Excision
Status: NOT_YET_RECRUITING
Conditions: Vulvar Cancer
Interventions: PROCEDURE: Re-excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis|Latent Tuberculosis|HIV/AIDS
Interventions: OTHER: Streamlined weekly DOT visits|OTHER: Weekly DOT visit reminders|OTHER: Cost reimbursement DOT|OTHER: 99DOTS|OTHER: Weekly SAT dosing reminders/check-ins|OTHER: Cost reimbursement SAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study
Status: RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Benzoyl Peroxide Cream for Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Benzoyl Peroxide|DRUG: Moisturizing Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: 500 mL/day of a beverage providing approximately 625 mg catechins|OTHER: Control beverage matched for energy and caffeine content
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Immunosuppression on HCV Recurrence After Living Donor Liver Transplantation - Comparative Study Between Tacrolimus + MMF and Tacrolimus + Steroid
Status: COMPLETED
Conditions: Hepatitis C|Liver Cirrhosis
Interventions: DRUG: tacrolimus + steroid|DRUG: tacrolimus + mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OBELIX Study: A Study of Avastin (Bevacizumab) in Combination With XELOX in Patients With Metastatic Cancer of the Colon or Rectum.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Oxaliplatin|DRUG: Xeloda
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Don't Throw Your Heart Away: Layperson Study 1
Status: COMPLETED
Conditions: Cardiac Transplant Disorder
Interventions: OTHER: Total Survival|OTHER: Stratified Transplant Survival
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Fumarate Hydratase Deficient Renal Cell Carcinoma|Succinate Dehydrogenase Deficient Renal Cell Carcinoma
Interventions: DRUG: Talazoparib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ACUTE AND CHRONIC EFFECTS OF A BOTANICAL EXTRACT ON ANXIETY, PERCEIVED STRESS, MOOD AND CORTISOL IN HEALTHY ADULTS
Status: COMPLETED
Conditions: Mood Disorders
Interventions: DIETARY_SUPPLEMENT: Proprietary, standardized botanical extract|DIETARY_SUPPLEMENT: Placebo (maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rituximab in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histopathological Techniques and PCR on Tissues Included in Paraffin for the Diagnosis of Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis|Diagnostic Techniques and Procedures|Sensitivity and Specificity|Polymerase Chain Reaction|Immunohistochemistry|Histochemistry
Interventions: OTHER: Histopathological study|OTHER: Molecular study (Polymerase chain reaction)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulsed Electromagnetic Field Stimulation and Charcot Foot Ulcer
Status: RECRUITING
Conditions: Charcot Foot Ulcer
Interventions: DEVICE: pulsed electromagnetic field therapy|DEVICE: Transcutanous electrical nerve stimulation|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Of Nasal HIV Vaccine Adjuvanted With LTK63
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Human Immunodeficiency Virus glycoprotein 140 (vaccine)|BIOLOGICAL: HIV glycoprotein 140 + Labile Toxin mutant LTK63 adjuvant|BIOLOGICAL: Labile Toxin mutant LTK63 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Abdominal Exercises and Russian Stimulation on The Abdominal Muscles Strength After Abdominoplasty
Status: UNKNOWN
Conditions: Abdominoplasty
Interventions: OTHER: Graduated abdominal strengthening exercises|DEVICE: The Russian current stimulation|OTHER: Combination Product: Graduated abdominal strengthening exercises and the Russian current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis
Status: UNKNOWN
Conditions: Periodontitis
Interventions: DEVICE: PerioWave|PROCEDURE: Scaling and Root Planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones
Status: COMPLETED
Conditions: Immunotherapy
Interventions: BIOLOGICAL: autologous Melan-A/MART-1 specific CTL clones
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)
Status: COMPLETED
Conditions: Endometriosis Related Pain|Overactive Bladder|Diabetic Neuropathic Pain|Refractory or Unexplained Chronic Cough
Interventions: DRUG: BAY1817080|DRUG: [14C]BAY1817080
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Bispectral Index Monitoring on Sedation Administration in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Intensive Care|Mechanically Ventilated Patients|Sedated Patients
Interventions: DEVICE: Bispectral Index Sedation monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)
Status: COMPLETED
Conditions: Metastatic or Locally Advanced Cancer
Interventions: DRUG: Ridaforolimus 100 mg|DRUG: Ridaforolimus 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Inhaled mannitol|DRUG: Matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESOLVE-AF: Clinical Evaluation of the Ablacath™ Mapping Catheter and Ablamap® System Utilizing Electrographic Flow (EGF) Mapping to Resolve Extra-PV Sources of Atrial Fibrillation and Guide Ablation Therapy.
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Fibrillation, Persistent|Atrial Fibrillation Paroxysmal|Arrhythmia|Arrhythmias, Cardiac|Atrial Flutter|Atrial Fibrillation, Paroxysmal or Persistent|Atrial Arrhythmia|Atrial Tachycardia
Interventions: DEVICE: EGF-Mapping and EGF-Guided Ablation of AF Sources|DEVICE: EGF-Mapping of AF Sources (no ablation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Multiple-Dose Study to Evaluate VIA-3196 in Healthy Subjects
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: Placebo|DRUG: VIA-3196
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Hypnosis without VR (HYP)|DEVICE: Hypnosis with VR (VRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on Periodontal Treatment in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Gingivitis|Periodontitis
Interventions: DRUG: Scaling and root planing plus placebo|DRUG: Scaling and root planing plus azythromycin|DRUG: Prophylaxis plus azythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
Status: UNKNOWN
Conditions: GBM|Depression
Interventions: DRUG: Escitalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss
Status: COMPLETED
Conditions: Age-Related Hearing Loss
Interventions: DRUG: AUT00063|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Daily Almond Intake as a Preload Before Meals Versus as a Snack Among Korean Adults
Status: COMPLETED
Conditions: Adult Young and Healthy
Interventions: OTHER: almond|OTHER: high-carbohydrate control food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose and Multiple Ascending Dose Study of Voriconazole Inhalation Powder in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Voriconazole Inhalation Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia
Status: NOT_YET_RECRUITING
Conditions: Endometrial Hyperplasia|Grade 1 Endometrial Cancer
Interventions: BEHAVIORAL: Telemedicine behavioral weight intervention|DRUG: Progestin|BEHAVIORAL: Enhanced usual care|DRUG: Levonorgestrel-releasing IUD.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparative Bioavailability Study of Lisinopril Tablets, 40 mg - Effect of Food Study
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fed Conditions
Interventions: DRUG: Lisinopril|DRUG: lisinopril|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Autologous Pure Platelet-rich Plasma in the Treatment of Tendon Disease
Status: UNKNOWN
Conditions: Rotator Cuff Tear|Lateral Epicondylitis|Achilles Tendinitis
Interventions: BIOLOGICAL: Ultrasound-guided pure platelet-rich-plasma (P-PRP) injection|BIOLOGICAL: Ultrasound-guided platelet-rich-plasma (PRP) injection|DRUG: Ultrasound-guided Compound betamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes, Recurrence Rates, and Treatment Needs in Polypoidal Choroidal Vasculopathy (PCV)
Status: RECRUITING
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DIAGNOSTIC_TEST: Indocyanine Green Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation
Status: TERMINATED
Conditions: Acute Lung Injury|Adult Respiratory Distress Syndrome
Interventions: OTHER: low-tidal-volume ventilation|OTHER: APRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Ovarian Carcinoma
Interventions: DRUG: Bevacizumab|DRUG: Atezolizumab|DRUG: Chemotherapy|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: levocetirizine (Xyzal)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study Assessing the Effect of Avapritinib Versus Best Available Therapy in Patients With AdvSM
Status: COMPLETED
Conditions: Advanced Systemic Mastocytosis|Aggressive Systemic Mastocytosis|Systemic Mastocytosis With an Associated Hematological Neoplasm|Mast Cell Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Beclometasone/Formoterol/Glycopyrrolate|DRUG: Beclometasone/Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Serum-derived EV for Venous Trophic Lesions Not Responsive to Conventional Treatments
Status: RECRUITING
Conditions: Ulcer Venous
Interventions: OTHER: Autologous extracellular vesicles from serum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellular Infection|HIV Infections
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Clarithromycin|DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Evaluating the Vein of MArshall Ethanol Infusion Ablation Using an Over-the-wire (OTW) Balloon Versus a microcatHeter in Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: Microcatheter|DEVICE: OTW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-precision Radiotherapy of Motor Deficits Due to Metastatic Spinal Cord Compression
Status: COMPLETED
Conditions: Spinal Cord Compression Due to Metastasis to Spine
Interventions: RADIATION: High-precision RT 5x5 Gy in 1 week
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response Of Arteriovenous Fistula Puncture-related Pain To Cryotherapy Application In Haemodialysis Patients
Status: RECRUITING
Conditions: Hemodialysis Complication
Interventions: OTHER: Ice packs (cryotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prior Statin Use and Risk of CHF, ALO and Malignant Arrhythmia in Indonesian Post-Acute Coronary Syndrome Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Acute Pulmonary Edema|Arrhythmias, Cardiac|Heart Failure
Interventions: DRUG: Statins (Cardiovascular Agents)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Pharmacokinetics and Food-Effect Bioavailability of Lubiprostone Sprinkle in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cohort 1: Lubiprostone Capsule, Fasted|DRUG: Cohort 1: Lubiprostone Sprinkle Formulation, Fasted|DRUG: Cohort 2: Lubiprostone Sprinkle Formulation, Fed|DRUG: Cohort 2: Lubiprostone Sprinkle Formulation, Fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer|ER Positive Breast Cancer|PR-Positive Breast Cancer
Interventions: DRUG: Neratinib|DRUG: Letrozole (L) or Anastrozole (A)|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Nicotinamide to Treat Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Nicotinamide|DRUG: Enduramide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Programmed Cryotherapy and Continuous Passive Motion After Computer-Assisted Total Knee Arthroplasty
Status: COMPLETED
Conditions: Patients With Osteoarthritis Undergoing CAS-TKA
Interventions: OTHER: Programed cryotherapy and continuous passive motion|OTHER: Unrogramed cryotherapy and continuous passive motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
Status: COMPLETED
Conditions: Contraception
Interventions: PROCEDURE: Bilateral Salpingectomy|PROCEDURE: Bilateral Tubal Ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GM-CSF With or Without Vaccine Therapy After Combination Chemotherapy and Rituximab as First-Line Therapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma
Status: SUSPENDED
Conditions: Lymphoma
Interventions: DRUG: autologous immunoglobulin idiotype-KLH conjugate vaccine|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: rituximab|DRUG: sargramostim|DRUG: vincristine|PROCEDURE: Intervention/procedure|PROCEDURE: antibody therapy|PROCEDURE: biological therapy|PROCEDURE: chemotherapy|PROCEDURE: colony-stimulating factor therapy|PROCEDURE: cytokine therapy|PROCEDURE: monoclonal antibody therapy|PROCEDURE: non-specific immune-modulator therapy|PROCEDURE: therapeutic procedure|PROCEDURE: tumor cell derivative vaccine|PROCEDURE: vaccine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening
Status: RECRUITING
Conditions: Pregnancy Outcome
Interventions: PROCEDURE: Outpatient Foley balloon placement|PROCEDURE: Inpatient Foley Balloon placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects
Status: RECRUITING
Conditions: Anesthesia Induction
Interventions: DRUG: ET-26|DRUG: Etomidate Injectable Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Y-90 Alone or With Sorafenib for Pre-Transplant Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: Yttrium-90 (Y-90)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IN10018 Monotherapy or in Combination With Docetaxel in Gastric or GEJ Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: IN10018|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MyStroke for Stroke Survivors and Caregivers
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute|Ischemic Stroke, Acute
Interventions: BEHAVIORAL: MyStroke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-pharmacological Methods on Pain
Status: NOT_YET_RECRUITING
Conditions: Pain|Infant ALL|Preterm
Interventions: PROCEDURE: Facilitated Tucking, Oral Breast Milk , Kangaroo Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Eight-Week Study Evaluating the Efficacy and Tolerability of Two Doses of SSR149415 in Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: SSR149415
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remimazolam vs. Propofol: Impact on Postoperative Delirium in Neurosurgical Patients
Status: RECRUITING
Conditions: Postoperative Delirium
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION