pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis
Interventions: DRUG: Amorolfine (Antifungal)|DRUG: RV4104A, Ciclopiroxolamine, Cyclopirox (Keratolytic Agents/Antifungal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma
Status: COMPLETED
Conditions: Glial Cell Tumors|Malignant Gliomas|Glioblastoma Multiforme|Anaplastic Astrocytoma|Gliomatosis Cerebri|Gliosarcoma|Brainstem Glioma|Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Valproic acid|DRUG: Bevacizumab|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center Study to Evaluate the Safety of Apixaban (BMS-562247) in Indian Subjects Undergoing Elective Total Knee Replacement or Total Hip Replacement Surgery
Status: COMPLETED
Conditions: Anticoagulation
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midfoot Fusion Bolt (MFB) in the Early Stage of Diabetic-neuropathic Charcot Feet
Status: TERMINATED
Conditions: Diabetes Mellitus 1 or 2|Midfoot Charcot Neuroarthropathy
Interventions: PROCEDURE: Surgery with Midfoot Fusion Bolt|PROCEDURE: Cast treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
Status: RECRUITING
Conditions: Postoperative Pain|Inguinal Hernia
Interventions: DRUG: Opioids|OTHER: No opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Steroid-Free Versus Steroid-Based Immunosuppression in Pediatric Renal (Kidney) Transplantation
Status: COMPLETED
Conditions: Kidney Diseases|Kidney Transplantation|Kidney Transplant|Renal Transplantation|Renal Transplant
Interventions: DRUG: Daclizumab|DRUG: Mycophenolate mofetil (MMF)|DRUG: Prednisone|DRUG: Tacrolimus|DRUG: Ganciclovir|DRUG: Valganciclovir|DRUG: Trimethoprim and sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of YZJ-1139 in Insomnia Disorder
Status: RECRUITING
Conditions: Insomnia Disorder
Interventions: DRUG: YZJ-1139 20mg|DRUG: YZJ-1139 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stepped Care Treatment for Common Mental Disorders Among Foreign Domestic Helpers
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Stepped Care Mental Health for Foreign Domestic Helpers (SCMH-FDH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GCSF Therapy in Decompensated Cirrhosis - A Double Blinded RCT
Status: UNKNOWN
Conditions: Decompensated Cirrhosis of Liver
Interventions: DRUG: G-CSF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coral Calcium's Effect on Bone Density in Postmenopausal Women With and Without Ibandronate
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DIETARY_SUPPLEMENT: Coral Complex 3|DRUG: Ibandronate|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, and PK of VX15/2503 In Patients With MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: VX15/2503|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meaning-Centered Psychotherapy at Home
Status: RECRUITING
Conditions: Nurse-Patient Relations|Psychology, Social
Interventions: BEHAVIORAL: Meaning-Centered Psychotherapy/MCP-PC Training|BEHAVIORAL: Meaning-Centered Psychotherapy/MCP-PC|BEHAVIORAL: Treatment As Usual/TAU
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trastuzumab, Lapatinib|DRUG: Pertuzumab, trastuzumab-emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults
Status: RECRUITING
Conditions: Liver Diseases
Interventions: DIETARY_SUPPLEMENT: Panax Ginseng C.A. Mey Extract group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Status: COMPLETED
Conditions: Labor Pain|Labor; Prolonged, Second Stage|Labor; Prolonged, First Stage
Interventions: DRUG: remifentanil|DRUG: combined spinal-epidural analgesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: [68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation
Status: RECRUITING
Conditions: Acute Cellular Graft Rejection|Cardiac Sarcoidosis|Myocarditis Due to Drug
Interventions: DRUG: [68Ga]Ga-PentixaFor PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Zanubrutinib Treatment in Patients With IgM Monoclonal Gammopathy and Antri-MAG Related Polyneuropathy
Status: RECRUITING
Conditions: Monoclonal Gammopathy of Uncertain Significance
Interventions: DRUG: Zanubrutinib Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis
Status: TERMINATED
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Lenabasum 5 mg|DRUG: Lenabasum 20 mg|OTHER: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Localized Provoked Vulvodynia Caused by Laxity of the Utero-Sacral Ligaments?
Status: COMPLETED
Conditions: Vulvodynia|Referred Pain
Interventions: PROCEDURE: Pressure-test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomechanical Effects of Three Types of Foot Orthoses in Individuals With Posterior Tibialis Tendon Dysfunction
Status: COMPLETED
Conditions: Posterior Tibial Tendon Dysfunction
Interventions: DEVICE: Foot Orthoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analgesia After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Periarticular Injection|DRUG: CFNB + Posterior Capsular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Antimonial Dosage in American Mucosal Leishmaniasis
Status: UNKNOWN
Conditions: Mucosal Leishmaniasis|Mucocutaneous Leishmaniasis
Interventions: DRUG: Meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline add-on to Antipsychotics for the Treatment of Negative and Cognitive Symptoms in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Minocycline|DRUG: Placebo|OTHER: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation for Perinatal Stroke Optimizing Recovery Trajectories
Status: COMPLETED
Conditions: Perinatal Stroke|Hemiplegic Cerebral Palsy
Interventions: DEVICE: Cathodal transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VAXCHORA Pediatric Study to Assess Safety and Immunogenicity
Status: COMPLETED
Conditions: Cholera (Disorder)
Interventions: BIOLOGICAL: VAXCHORA (Cholera Vaccine, Live, Oral)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy Safety and Efficacy Study
Status: RECRUITING
Conditions: Multiple System Atrophy
Interventions: DRUG: TEV-56286|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Digital Exercise Intervention in Patients With Spondyloarthritis
Status: NOT_YET_RECRUITING
Conditions: Spondyloarthritis|Exercise
Interventions: BEHAVIORAL: Exercise with supervision|BEHAVIORAL: Exercise without supervision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Bee-buzzy Vibrating Cold Application and Marionette Doll on Pain and Fear During Phlebotomy
Status: RECRUITING
Conditions: Fear of Pain
Interventions: OTHER: bee-buzzy vibrating cold application marionette doll|OTHER: Rotuine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infliximab and Classic DMARDs in the Rheumatoid Arthritis Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis（RA）
Interventions: DRUG: Infliximab group|DRUG: Classic DMARDs treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate-Intensity Interval Training (MIIT) on Mental Toughness, Sports Motivation, Athlete Burnout, Perceived Stress, Unforced Errors and Performance of Competitive Badminton Players in China
Status: COMPLETED
Conditions: Burnout，Motivation，Stress，Mental Toughness
Interventions: BEHAVIORAL: Moderate-Intensity Interval Training (MIIT)|BEHAVIORAL: High-Intensity Interval Training (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cystoscopy and Cystodistension; Therapeutic and Aetiological Aspect in Overactive Bladder
Status: COMPLETED
Conditions: Urinary Incontinence, Urge
Interventions: PROCEDURE: Cystodistension & Cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CESI With Low Dose Lidocaine and Transient Weakness
Status: COMPLETED
Conditions: Cervical Radiculitis|Pain
Interventions: DRUG: Experimental Group 1 triamcinolone and lidocaine|DRUG: Experimental Group 2 triamcinolone and saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study Combining Oral Capecitabine (Xeloda) and Radiotherapy for Patients With Unresectable Liver or Cholangiocarcinoma
Status: TERMINATED
Conditions: Cancer of Liver
Interventions: DRUG: Capecitabine (Xeloda)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Preoperative Carbohydrates Drinks, Dichloroacetate and Exercise on Postoperative Muscle Insulin Resistance
Status: UNKNOWN
Conditions: Insulin Resistance
Interventions: DRUG: Dichloroacetate|DIETARY_SUPPLEMENT: Carbohydrate drinks|BEHAVIORAL: Moderate intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PMCF Neo Pedicle Screw and Cage Systems
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease|Spondylolisthesis|Spinal Stenosis|Spinal Tumor|Trauma|Pseudoarthrosis of Spine
Interventions: DEVICE: NEO Pedicle Screw System™|DEVICE: Neo Cage System™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Pecto Intercostal Fascial Plane Block After Open Heart Surgeries
Status: COMPLETED
Conditions: Pain, Chest
Interventions: DEVICE: ultrasound|DRUG: Bupivacaine Hydrochloride 5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects Of Jaw Sensorimotor System In The Treatment Of Neck Pain And Dysfunction
Status: COMPLETED
Conditions: Neck Pain|PHYSIOTHERAPY|JAW
Interventions: OTHER: Jaw opening-closing movements|OTHER: Specific Active exercises|OTHER: Exercise Therapy|OTHER: Supportive Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relieving Acute Pain (RAP) Study: A Pilot Study
Status: TERMINATED
Conditions: Trauma|Opioid Use|Spine Fusion
Interventions: DRUG: Oxycodone|DRUG: Ketorolac|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Therapy|DRUG: Midomafetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Systemic NO-Inhibition on Renal Hemodynamics in Patiens With Polycystic Kidney Disease and Chronic Glomerulonephritis
Status: COMPLETED
Conditions: ADPKD|Glomerulonephritis
Interventions: DRUG: Ng-monomethyl-L-arginine (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose:
Clinical trial: Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures
Status: TERMINATED
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Black Rice Anthocyanin in Mixed Meals: Influence on Postprandial Glycaemic and Lipid Responses Among Healthy Individuals
Status: COMPLETED
Conditions: Postprandial Hyperglycemia|Lipidemia
Interventions: DIETARY_SUPPLEMENT: Anthocyanin fortified bread with beef patty (35% fat)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel and S-1 Followed By Radiation Therapy and Low-Dose Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: tegafur-gimeracil-oteracil potassium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Iptacopan (LNP023)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity and Safety of Heterologous SARS-CoV-2 Vaccine Schemes in an Elderly Population
Status: UNKNOWN
Conditions: COVID-19 Vaccines
Interventions: DRUG: Gam-COVID-Vac / Gam-COVID-Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of a Diuretic Algorithm in Clinical Stability in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Furosemide and Phone contact|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Brazikumab (MEDI2070) in Participants With Active, Moderate to Severe Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Brazikumab IV Infusion|DRUG: Brazikumab SC Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Gastric Cancer|Lung Cancer|Ovarian Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: MVF-HER-2(628-647)-CRL 1005 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of a2 Platinum Stage 1 Infant Formula on Infant Digestion and Comfort
Status: COMPLETED
Conditions: Healthy Infants
Interventions: OTHER: a2 Platinum® stage 1 infant formula|OTHER: Conventional, A1 and A2 β-casein containing stage 1 infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Lurbinectedin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Interval After Gastric Emptying and Quality of Bowel Cleansing
Status: RECRUITING
Conditions: Colonoscopy
Interventions: OTHER: after ultrasound gastric assessment to ensure gastric empty, painless colonoscopy was performed within 2 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Interventions on the Progression of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis of the Knees
Interventions: DRUG: Diacerien|DRUG: Glucosamine/Chondroitin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer
Status: COMPLETED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: graft versus host disease prophylaxis/therapy|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose of Amoxicillin and Metronidazole Plus Bismuth For Helicobacter Pylori Treatment
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Amoxicillin, Metronidazole|DRUG: Bismuth Potassium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EBUS-TBNA vs Flex 19G EBUS-TBNA
Status: COMPLETED
Conditions: Lymphadenopathy|Lung Cancer|Sarcoidosis|Lymphoma
Interventions: DEVICE: Flexible 19G EBUS-TBNA needle|DEVICE: 21G EBUS-TBNA needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene
Status: TERMINATED
Conditions: Leukemia|Myeloma|Myeloproliferative Diseases
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: Alemtuzumab|PROCEDURE: Stem Cell infusion|DRUG: Tacrolimus|DRUG: Mini Methotrexate|DRUG: G-CSF|PROCEDURE: Donor Lymphocyte Infusion (DLI)|DRUG: AP1903|DRUG: Methylprednisolone|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Recombinant Human Growth Hormone (rhGH) in the Treatment of Children With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: rhGH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Coronally Advanced Root Coverage Procedure With Collagen Matrix and Connective Tissue Graft
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Ossix volumax collagen matrix|PROCEDURE: Connective Tissue Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Efficacy of NMS-01940153E in Adult Patients With Unresectable Hepatocellular Carcinoma (HCC) Previously Treated With Systemic Therapy
Status: COMPLETED
Conditions: Unresectable Hepatocellular Carcinoma (HCC)
Interventions: DRUG: NMS-01940153E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Flavocoxid (Limbrel) Versus Naproxen in Subjects With Moderate-Severe Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Flavocoxid 500 mg|DRUG: Naproxen|OTHER: Placebo|OTHER: flavocoxid 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tencel vs. Standard Cotton Therapeutic Garments as an Adjunct Treatment for Moderate to Severe Atopic Dermatitis in Children
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DEVICE: Tencel Therapeutic Garments|DEVICE: Cotton Therapeutic Garments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Muscle Vibration Versus Muscle Energy Technique In Sacroiliac Joint Dysfunction
Status: RECRUITING
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Local Muscle Vibration compared to Muscle energy technique in SIJD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetics, Safety, and Tolerability of ABBV-903 in Healthy Japanese and Han Chinese Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-903|DRUG: Placebo for ABBV-903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Olive Polyphenols in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Olive Polyphenols|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Turmeric on Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Proteinuria
Interventions: DRUG: Turmeric extract|DRUG: Angiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Girdle Pain Symptom Severity in Pregnant Women With Gestational Diabetes Mellitus
Status: UNKNOWN
Conditions: Pregnant Women|Gestational Diabetes|Pelvic Girdle Pain
Interventions: OTHER: Evaluation of pain|DIAGNOSTIC_TEST: Evaluation of pelvic girdle pain diagnostic tests|OTHER: Evaluation of activity limitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Therapeutic Equivalence Study of Two Metronidazole Gel 1% Topical Treatments of Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea|Erythematotelangiectatic Rosacea
Interventions: DRUG: Reference: Metronidazole Gel 1%|DRUG: Test: Metronidazole Gel 1%|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of Continent Catheterizable Channel : Native Bladder or Enterocystoplasty ?
Status: UNKNOWN
Conditions: Neurogenic Bladder|Continent Cutaneous Urinary Diversion|Mitrofanoff
Interventions: PROCEDURE: Native bladder implantation|PROCEDURE: Enterocystoplasty implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Hematologic Malignancies With Single-Unit or Double-Unit Cord Blood Transplantation
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia|Non-Hodgkin Lymphoma|Myelodysplastic Syndromes
Interventions: PROCEDURE: Cord Blood Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3023414 and Necitumumab in Squamous Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: LY3023414|DRUG: Necitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Endoscopic Mucosal Resection Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colonic Polyp|Colonoscopy|Complication|Recurrence
Interventions: PROCEDURE: Cold snare EMR|PROCEDURE: Hot snare EMR|PROCEDURE: Eleview injection|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprascapular and Axillary Blocks Versus Interscalene Block for Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DRUG: Suprascapular & axillary blocks|DRUG: Interscalene block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK in Pts With HRPC & Skeletal Metastes
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 chloride (Xofigo®, BAY88-8223) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical & Radiographic Evaluation of Zinc Oxide-Ozonated Oil as a New Primary Root Canal Filling
Status: COMPLETED
Conditions: Pulp Disease, Dental|Obturation|Root Canal Infection
Interventions: PROCEDURE: pulpectomy procedure and the clinical evaluation|RADIATION: radiographic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shorten the Time Required to Correct the Arrival of Complete Oral Feeding in Premature Infants
Status: COMPLETED
Conditions: Premature Infants
Interventions: BEHAVIORAL: Complete oral feeding intervention|BEHAVIORAL: Routine nursing care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial
Status: RECRUITING
Conditions: Glaucoma|Acupuncture|Intraocular Pressure
Interventions: OTHER: Acupuncture|OTHER: Acupuncture placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors
Status: COMPLETED
Conditions: Malignant Salivary Gland Neoplasm|Recurrent Salivary Gland Carcinoma|Salivary Gland Adenoid Cystic Carcinoma|Stage IV Major Salivary Gland Cancer AJCC v7
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The STOP-MED CTRCD Trial
Status: RECRUITING
Conditions: Heart Failure|Cardiotoxicity|Cardiac Toxicity|Antineoplastics Toxicity|Cancer
Interventions: OTHER: Stopping Heart Failure Medication(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LOXO-305|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dexmedetomidine on Respiratory Function and Inflammatory Responses in Patient With Sepsis Undergoing Cleaning Focus of Infection
Status: UNKNOWN
Conditions: Organ Protection
Interventions: DRUG: dexmedetomidine|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Liver Fibrosis and Steatosis Assessment With Fibroscan and iLivTouch
Status: COMPLETED
Conditions: Chronic Liver Disease|Liver Fibrosis|Liver Steatoses
Interventions: DIAGNOSTIC_TEST: iLivTouch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectivity of Anti Tuberculosis Therapy in Idiopathic Uveitis With Positive IGRA
Status: ENROLLING_BY_INVITATION
Conditions: Tuberculous Uveitis
Interventions: DRUG: Anti Tuberculosis Drug|DRUG: Prednisone tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects
Status: COMPLETED
Conditions: Orphan Cholestatic Liver Diseases|Progressive Familial Intrahepatic Cholestasis|Alagille Syndrome|Primary Biliary Cirrhosis
Interventions: DRUG: 3 mg [14C]-A4250 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: vepdegestrant|DRUG: PF-07220060
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pramipexole for Anhedonic Depression
Status: RECRUITING
Conditions: Psychiatric Disorders Mood|Anhedonia|Depression
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Lennox-Gastaut Syndrome
Status: WITHDRAWN
Conditions: Lennox-Gastaut Syndrome
Interventions: DRUG: Cannabidiol Oral Solution|DRUG: Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase2 of A-101 Topical Solution in Subjects With Common Warts
Status: COMPLETED
Conditions: Common Wart
Interventions: DRUG: A-101 Topical Solution|DRUG: A-101 Vehicle Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Exercise Performance in Patients With Respiratory Disease at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-Label, Pilot Study to Evaluate the Efficacy of Narrowband Ultraviolet-B Phototherapy Three Times Weekly for Twelve Weeks in Moderate-to-Severe Psoriasis Patients
Status: RECRUITING
Conditions: Psoriasis
Interventions: DEVICE: Narrowband UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Russian Clinical Trial of Mesenchymal Cells in Patients With Septic Shock and Severe Neutropenia
Status: UNKNOWN
Conditions: Septic Shock|Nonchemotherapy Drug-induced Neutropenia|Neutropenia After Chemotherapy in Oncohematological Patients|Neutropenia in Patients With Aplastic Anemia
Interventions: GENETIC: Mesenchymal stromal cells|DRUG: Standard therapy of septic shock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between Two Oral Formulations of Diphenhydramine Hydrochloride
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DRUG: Diphenhydramine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: enteric-coated mycophenolate sodium|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: YM087 oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From Cerebral Hemorrhage
Status: UNKNOWN
Conditions: Lung Infection|Cerebral Hemorrhage|Pneumonia
Interventions: DRUG: rhubarb|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial for Evaluation of the Safety, Pharmacokinetics, and [18F] Radiation Dosimetry of CTT1057
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: CTT1057|PROCEDURE: Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Sensitive Prostate Cancer|Prostate Cancer|Cancer of the Prostate
Interventions: DRUG: Enzalutamide|DRUG: Placebo (No longer applicable in Open Label study period)|DRUG: Leuprolide Open Label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zolpidem Tartrate 10 mg Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zolpidem 10 mg tablets|DRUG: AMBIEN® 10 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets
Status: COMPLETED
Conditions: Rheumatic Diseases
Interventions: DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen|DRUG: Tramadol/acetaminophen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interferon Alfa With or Without Isotretinoin in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: chemotherapy|DRUG: isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy Study of Nicotine Gel to Treat Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: ATG002 (study drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of ABT-199 in Subjects With Acute Myelogenous Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|AML|Acute Myeloid Leukemia
Interventions: DRUG: ABT-199
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILOPROST in Septic Shock With Persistent Microperfusion Defects (I-MICRO)
Status: COMPLETED
Conditions: Septic Shock Hyperdynamic
Interventions: DRUG: ILOPROST|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine Called CTB+AVP in Healthy Adult People.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: PF-07612577|DRUG: PF-06264006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain|Anxiety|Depression
Interventions: DEVICE: EaseVRx|DEVICE: Sham VR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study, Evaluating the Efficacy of Regulatory T-cell Suppression by Ontak in Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Ontak
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Montelukast for Prevention & Treatment of OHSS
Status: SUSPENDED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: dydrgesterone 10 mg( tab)/12hs/14 days|COMBINATION_PRODUCT: montelukast 10 mg(tab) oral/24hs/ 7 days dydrgesterone 10 mg( tab) oral/12hs/14 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Arbaclofen Placarbil SR|DRUG: Arbaclofen Placarbil MR Prototype A|DRUG: Arbaclofen Placarbil MR Prototype B|DRUG: Arbaclofen Placarbil IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Vasculera® in the Healing of Diabetic Skin Ulcers
Status: WITHDRAWN
Conditions: Diabetic Ulcers
Interventions: DIETARY_SUPPLEMENT: Vasculera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF)
Status: COMPLETED
Conditions: Permanent Atrial Fibrillation
Interventions: DRUG: Bisoprolol|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of a Remotely-delivered, Racially-tailored Exercise Training Program for Immediate and Sustained Improvements in Walking Dysfunction, Symptoms, and Health-related Quality of Life (HRQOL) Among African-Americans With Multiple Sclerosis (MS) Residing in Rural Environments.
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Guidelines for Exercise in Multiple Sclerosis (GEMS)|BEHAVIORAL: FLEX Stretching and Toning Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Effect of the Change of Efavirenz (EFV) for Lopinavir/Ritonavir (LPV/r) in Lipoatrophy in HIV-infected Patients
Status: COMPLETED
Conditions: HIV Infections|Lipoatrophy
Interventions: DRUG: EFV|DRUG: LPV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-directed Versus Therapist-directed Re-loading on Incidence of Ulcer Recurrence
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: BEHAVIORAL: Therapist-Directed Re-loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery
Status: COMPLETED
Conditions: Hyperinsulinemic Hypoglycemia
Interventions: DRUG: Glucagon RTU|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Therapy for Managing Obesity in People With Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Obesity|Overweight
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT) for managing Obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors (Excluding Gastric Cancer and Breast Cancer)
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT