pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Influenza Vaccination at a Reduced Dose Using Mesotherapy in HIV/AIDS Patients at the Hadassah AIDS Center, Jerusalem
Status: UNKNOWN
Conditions: Influenza|Acquired Immune Deficiency Syndrome|HIV Infections
Interventions: BIOLOGICAL: Mesotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerofit Post Market Investigation
Status: RECRUITING
Conditions: Transfemoral Amputation|Amputation|Skin Health
Interventions: DEVICE: AeroFit Seal-In Liner / Socket|DEVICE: Seal-In Silicone Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TNP-2198 Capsules in Asymptomatic Participants With Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: TNP-2198|DRUG: TNP-2198 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0306, Irinotecan in Treating Patients With Recurrent or Refractory Advanced Transitional Cell Cancer of the Urothelium Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter|Urethral Cancer
Interventions: DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Esmolol Early Post Operative Cognitive Dysfunction
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: DRUG: Esmolol Hydrochloride|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Instrument Assisted Soft Tissue Mobilization and Bowen Technique in Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia|Low Back Pain
Interventions: OTHER: Graston Technique (Instrumented assisted soft tissue mobilization)|OTHER: Bowen's Technique(Soft tissue technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin for the Treatment of Glabellar Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Virtual Simulation Training in Essential Newborn Care for Healthcare Workers in Low and Middle Income Countries
Status: ENROLLING_BY_INVITATION
Conditions: Resuscitation
Interventions: OTHER: Virtual Essential Newborn Care (vENC) training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: SKB264|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: umBilical Or Adult Donor Red Blood Cells in Extremely Low Gestational Age Neonates and Retinopathy of Prematurity (BORN)
Status: RECRUITING
Conditions: Retinopathy of Prematurity
Interventions: BIOLOGICAL: cord blood-RBC concentrates|BIOLOGICAL: adult donor RBC concentrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Excision of Lymph Node Trial (EXCILYNT) (Mel69)
Status: RECRUITING
Conditions: Melanoma
Interventions: PROCEDURE: Excision of clinically detected lymph node metastasis before any systemic therapy|PROCEDURE: Excision of clinically detected lymph node metastasis after neoadjuvant systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Continuing Olanzapine to Switching to Quetiapine in Overweight or Obese Patients With Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Olanzapine|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Cardiac Adrenergic Function Explored by I-123-MIBG and CZT Camera (D-SPECT) Versus Anger Camera in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: I-123-MIBG|DEVICE: CZT Camera (D-SPECT)|DEVICE: Anger Camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PCM Cervical Disc System
Status: COMPLETED
Conditions: Radiculopathy|Myelopathy
Interventions: DEVICE: Anterior Cervical Discectomy and Fusion (ACDF)|DEVICE: PCM Cervical Disc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omalizumab for Lupus
Status: COMPLETED
Conditions: Systemic Lupus Erthematosus|Sjogren's Syndrome
Interventions: DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nasal CPAP on Lipid Profile in Patients With Dyslipidaemia and Sleep Apnea
Status: WITHDRAWN
Conditions: Sleep Apnea|Dyslipidaemia
Interventions: DEVICE: Continuous positive airway pressure|BEHAVIORAL: Intensive lifestyle intervention|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor
Status: RECRUITING
Conditions: Heart Failure|Cognitive Impairment|Dementia|Left Ventricular Dysfunction|Cognitive Change|Cognitive Decline
Interventions: OTHER: Disease management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multi-center Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot Ulcer
Status: RECRUITING
Conditions: Diabetic Foot Ulcer Treatment
Interventions: DRUG: Yunnan Baiyao
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Healthy Sample)
Status: COMPLETED
Conditions: Catastrophizing Coronavirus (COVID-19)
Interventions: OTHER: Meditation (1 x 20-minute guided audio training)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Coaching and Counseling for Bipolar Patients: Dealing With Moments of Crisis in Times of COVID-19.
Status: COMPLETED
Conditions: To Determine the Incidence of Depression in Subjects Affected by Bipolar Disorder
Interventions: OTHER: Counseling and Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mesenchymal Stem Cell Therapy for Lung Rejection
Status: COMPLETED
Conditions: Lung Transplant Reject|Bronchiolitis Obliterans
Interventions: BIOLOGICAL: Mesenchymal stem cell 0.5|BIOLOGICAL: Mesenchymal stem cell 1.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Micro-anatomy of the Menisci and Cartilage After Isolated Acute ACL Injury With MRI at 7T
Status: TERMINATED
Conditions: Meniscus Lesion|Cartilage Injury|ACL Injury
Interventions: DEVICE: Ultrahigh Field MRI at 7T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bingocize: A Novel Mobile Application for Older Adult Health
Status: COMPLETED
Conditions: Activities of Daily Living|Accidental Fall|Sarcopenia|Arteriosclerosis|Diabetes Mellitus, Type 2|Hypertension|Cognitive Decline|Executive Function|Cognitive Aging
Interventions: BEHAVIORAL: Socially-Based Exercise Intervention for Older Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Nivolumab, Nivolumab in Combination With Ipilimumab and Placebo in Participants With Localized Kidney Cancer Who Underwent Surgery to Remove Part of a Kidney
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: nivolumab|BIOLOGICAL: ipilimumab|DRUG: nivolumab placebo|DRUG: ipilimumab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of a New Specific Infant Formula in Case of Functional Constipation
Status: RECRUITING
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: new infant formula|DIETARY_SUPPLEMENT: Standard formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Solid Tumors|Programmed Cell Death-1 (PD1, PD-1)|Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)|Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)
Interventions: BIOLOGICAL: Sacituzumab tirumotecan|BIOLOGICAL: Pembrolizumab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Insomnia vs. Exposure, Relaxation, and Rescripting Therapy
Status: COMPLETED
Conditions: Insomnia|Nightmare|Trauma
Interventions: BEHAVIORAL: CBT-I|BEHAVIORAL: ERRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleeve Gastrectomy With Jejuno-ileal Bypass Versus Single Anastomosis Sleeve Jejunal Bypass
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: SGJIB|PROCEDURE: SAS-JB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic System for Cataract Characterization and Optimal Phacoemulsification Energy Evaluation
Status: UNKNOWN
Conditions: Cataract|Ultrasound Therapy; Complications
Interventions: DEVICE: Eye Scan Ultrasound System (ESUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Comparing 19 and 25-gauge EUS-FNA Needles
Status: COMPLETED
Conditions: Cancer of Pancreas|Pancreatic Neoplasm
Interventions: PROCEDURE: Pancreatic Biopsy|PROCEDURE: Histological Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability Study of Oral EUR-1100 to Treat Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: EUR-1100|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Music Therapy Respiratory Protocol on Post-Covid-19 Respiratory Symptoms
Status: COMPLETED
Conditions: Post Covid-19 Respiratory|Dyspnea|SARS-CoV 2
Interventions: OTHER: Respiratory Music Therapy Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation
Status: UNKNOWN
Conditions: Infertility|Infertility, Male
Interventions: DEVICE: Ohana IVF Sperm Preparation Kit (OHB035)|DEVICE: Standard IVF Preparation Kit (OHB037)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Shoulder
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time Restricted Feeding on Weight Loss and Cardio-protection (TREATY Trial)
Status: COMPLETED
Conditions: Obesity|Time Restricted Feeding|Weight Loss|Calorie Restriction
Interventions: BEHAVIORAL: Time restricted feeding|BEHAVIORAL: Continuous Energy Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Axitinib in Patients With Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Axitinib (AG-013736)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplant in HIV Patients (BMT CTN 0803)
Status: COMPLETED
Conditions: Lymphoma|HIV
Interventions: PROCEDURE: Autologous transplant|DRUG: BCNU|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
Status: COMPLETED
Conditions: Angina Pectoris|Unstable Angina|Myocardial Infarction
Interventions: PROCEDURE: Percutaneous Coronary Revascularization|DRUG: Hemoglobin-Based Oxygen Carrier-201 (HBOC-201)|DRUG: Voluven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting in Ambulatory Surgery
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: Ear seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy and Safety of LY2940094 in Participants With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2940094|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Rovalpituzumab tesirine|DRUG: Topotecan|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biological Therapy on Biomarkers in Patients With Untreated Hepatitis C, Metastatic Melanoma, or Crohn Disease
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: infliximab|BIOLOGICAL: pegylated interferon alfa|BIOLOGICAL: ticilimumab|DRUG: ribavirin|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants
Status: COMPLETED
Conditions: Prophylaxis Of Invasive Fungal Infections
Interventions: DRUG: voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open Label, Single Arm, Multicenter Phase II Study of BYL719 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck Who Failed to Respond to Platinum-based Therapy.
Status: UNKNOWN
Conditions: Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant for Patients With Blood Malignancy Using Donors and Less Toxic Chemotherapy With CAMPATH 1H
Status: COMPLETED
Conditions: Myelodysplastic Disorders|Leukemia|Multiple Myeloma|Plasma Cell Dyscrasia|Lymphoproliferative Disorders
Interventions: DRUG: FLUDARABINE|DRUG: CAMPATH 1H|DRUG: FK50|PROCEDURE: Stem Cell Collection and Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: AcceleDent Aura|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical Cetirizine in Androgenetic Alopecia in Females
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: Topical cetirizine|DRUG: Placebo|DRUG: Topical minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bilateral Internal Iliac Artery Balloon Occlusion in Placenta Accreta Spectrum Management
Status: RECRUITING
Conditions: Internal Iliac Artery|Balloon Occlusion|Placenta Accreta Spectrum
Interventions: PROCEDURE: Conventional management|PROCEDURE: Bilateral internal iliac artery balloon occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of THR-18 When Administered to Patients Suffering Acute Ischemic Stroke and Treated With Tissue Plasminogen Activator (tPA)
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: THR-18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of BPI-442096 in Advanced Solid Tumor Patients
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor|Non-small Cell Lung Cancer|Pancreatic Cancer|Colorectal Cancer
Interventions: DRUG: BPI-442096
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Risk of Cognitive Deficit After Surgery of Epilepsy by Dynamic Spectral Imaging (ISD) of the Cognitive Functions in Patients Explored in StereoElectroEncephaloGraphy (SEEG)
Status: RECRUITING
Conditions: Epilepsy
Interventions: PROCEDURE: Dynamic Spectral Imaging (ISD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid Malignancies
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia (AML)|B-cell Non-Hodgkin's Lymphoma (B-NHL)|Multiple Myeloma (MM)|T-Cell Leukemia/Lymphoma, Adult|B-cell Acute Lymphoblastic Leukemia (B-ALL)
Interventions: BIOLOGICAL: Autologous CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DEVICE: citrate regional anticoagulation|DEVICE: citrate regional anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate Low-Dose Fractionated Radiotherapy (LDFRT)
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: RADIATION: Low-Dose Fractionated Radiation Therapy/Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon Alfa Plus Thalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: thalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SG2501 Safety Study in Subjects With Relapsed or Refractory Hematological Malignancies and Lymphoma.
Status: RECRUITING
Conditions: Hematological Malignancy|Lymphoma
Interventions: DRUG: SG2501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Energy Drink on Sport Performance and Psycho-Physiological Responses.
Status: COMPLETED
Conditions: Physical Activity
Interventions: DIETARY_SUPPLEMENT: Energy Drink|DIETARY_SUPPLEMENT: Placebo Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacosurveillance and Pharmacogenetics of First-line Diuretics in Hypertension: The StayOnDiur Study
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: thiazides|PROCEDURE: Non thiazidic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Spiration IBV® Valve System and Spiration Airway Sizing Kit
Status: WITHDRAWN
Conditions: Management of BPF (Bronchopleural Fistulae)
Interventions: DEVICE: treatment with valves (The Spiration® IBV Valve System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of a Point-of-care Sputum Specimen Assay at the Emergency Department for Patients Suspected of Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Bacterial
Interventions: DIAGNOSTIC_TEST: POC-PCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Sublingual TNX-102, Oral and Intravenous Cyclobenzaprine in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: SL TNX-102 2.4 mg at pH 3.5|DRUG: SL TNX-102 2.4 mg at pH 7.1|DRUG: Cyclobenzaprine Tablet|DRUG: Cyclobenzaprine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of FB2001 for Inhalation in Healthy Chinese Adults
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: DRUG: FB2001 for inhalation|DRUG: FB2001 for inhalation placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Flexible Thoracolumbar Brace on Idiopathic Scoliosis, Prospective, Randomized, Open-label Trial
Status: TERMINATED
Conditions: Scoliosis Idiopathic
Interventions: DEVICE: scoliosis brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-finding Study in Platinum-Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Platinum-resistant Ovarian Cancer
Interventions: DRUG: GSK2110183 in combination with carboplatin and paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spironolactone Administration to Prevent Ischemic Kidney Injury in Critically Ill Cancer Patients
Status: UNKNOWN
Conditions: Critically Ill|Cancer
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Perianal Fistulizing Crohn's Disease
Status: COMPLETED
Conditions: Fistulizing Crohn's Disease
Interventions: DRUG: Filgotinib|DRUG: Placebo to match filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates
Status: TERMINATED
Conditions: Infection Associated With Catheter|Bacteremia|Sepsis
Interventions: DRUG: Ethanol lock|DRUG: Heparinized saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: E-23596 - Use of NCPAP Cycling to Wean Preterm Infants
Status: TERMINATED
Conditions: Premature Birth
Interventions: OTHER: NCPAP cycling|OTHER: NCPAP continuous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Concurrent Chemoradiation and Durvalumab for Locoregionally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucosal Immunity: Influence on Infectious Viral Load: a Prospective Observational Study
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection|Influenza Viral Infections|Virus Shedding|Mucosal Immunity|RSV Infection
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dermacyd Femina Pocket BR (Lactic Acid)- Acceptability.
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd Femina Pocket BR (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Nab-paclitaxel|DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Nab-paclitaxel|DRUG: Carboplatin|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Granulocyte colony-stimulating factor (G-CSF)|DRUG: Granulocyte-macrophage colony-stimulating factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Goal-directed Hemodynamic Therapy in Radical Cystectomy
Status: COMPLETED
Conditions: Bladder Cancer|Radical Cystectomy
Interventions: OTHER: Goal-directed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vacuum Therapy and Stabilization Splints Efficacious for the Management of Temporo-mandibular Joint Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: vacuum therapy|DEVICE: maxillary stabilization splint (MSS)|DEVICE: vacuum therapy VT and maxillary stabilization splint (MSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block forTranscatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Aortic Diseases
Interventions: DRUG: Postoperative analgesia management|DRUG: PENG-Bupivacaine|DRUG: Local infiltration-Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dispatch of Emergency Call Using Video Streaming Compared With Traditional Telephone Communication
Status: COMPLETED
Conditions: Emergency Medical Dispatch Centre|Video Streaming|Emergency Call|Prehospital Emergency Medical Services
Interventions: DEVICE: Video streaming (smartphone camera)|DEVICE: Telephone (telephone microphone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Essential Fatty Acid Nutrition For 1-2 Yr-Olds
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: DIETARY_SUPPLEMENT: LCPUFA Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-term Treatment Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA)
Status: COMPLETED
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: MRA(Tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy for the Prevention of Taxane-Induced Sensory Neuropathy of the Hands and Feet in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: DEVICE: Medical Device Usage and Evaluation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Effectiveness of U-90152 in HIV-1 Infected Patients Who Take Zidovudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Delavirdine mesylate|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Familial Atherosclerosis Treatment Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Arteriosclerosis|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: lovastatin|DRUG: colestipol|DRUG: niacin|OTHER: Placebo for colestipol|OTHER: Placebo for lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Knee Cartilage Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: PROCEDURE: Arthroscopic partial menisectomy|OTHER: Standard physical therapy|OTHER: Postoperative rehabilitative physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety, Pharmacodynamics and Efficacy of SHR-1703 in Eosinophilic Asthma Patients
Status: NOT_YET_RECRUITING
Conditions: Eosinophilic Asthma Patients
Interventions: DRUG: SHR-1703 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes
Status: COMPLETED
Conditions: Non-Insulin-Dependent Diabetes Mellitus
Interventions: DRUG: metformin|DRUG: sulphonylurea|DRUG: Avandamet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of 10% Potassium Hydroxide Solution Versus Cryotherapy in Molluscum Contagiosum
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: Group A received cryotherpay|DRUG: Group B received 10% Potassium Hydroxide Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Fabulous Stent Graft System for Stanford B Aortic Dissection
Status: COMPLETED
Conditions: Aortic Dissection Type B
Interventions: DEVICE: Fabulous Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies
Status: RECRUITING
Conditions: Pulpitis
Interventions: DRUG: non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies|DRUG: eugenol based zinc oxide and Ferric Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EASE (Efficacy of ATX01 Study in Erythromelalgia)
Status: COMPLETED
Conditions: Erythromelalgia
Interventions: DRUG: Amitriptyline Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Ulmus macrocarpa water extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Pilot Study of Floseal for the Treatment of Anterior Epistaxis in Patients With (HHT)
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia (HHT)|Epistaxis
Interventions: DRUG: Floseal|OTHER: Packing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Pain of Oral Sucrose Versus Placebo in Children 1 to 3 Months Old Needing Venipuncture
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 88% sucrose po solution|DRUG: placebo po
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol
Status: COMPLETED
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: DRUG: Letrozole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Hypopressive Exercises in Women With Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Prolapse; Female
Interventions: OTHER: Pelvic Floor Muscle Training|OTHER: Hypopressive Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Viral Replication by Tonate Virus (TONV) and Zika Virus (ZIKV), Within an ex Vivo Trophoblast and Placental Model
Status: UNKNOWN
Conditions: Zika Virus Infection
Interventions: BIOLOGICAL: Cell line and virus|BIOLOGICAL: Infection of human placental culture explants|BIOLOGICAL: Determination of viral load in tissues by qRT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: CD40 agonist mitazalimab in combination with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASA404 in Combination With Carboplatin/Paclitaxel/Cetuximab in Treating Patients With Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Tumors
Interventions: DRUG: ASA404|DRUG: Cetuximab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Episodic Future Thinking, Loss Aversion and Cigarette Smoking
Status: NOT_YET_RECRUITING
Conditions: Tobacco Smoking
Interventions: BEHAVIORAL: Episodic Future Thinking|BEHAVIORAL: Control Episodic Thinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy
Status: COMPLETED
Conditions: Chronic Gout
Interventions: DRUG: SEL-212|DRUG: KRYSTEXXA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Corneal Cross-linking With Different Riboflavin Solutions
Status: COMPLETED
Conditions: Keratoconus
Interventions: DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy and Movement Control Exercises for Chronic Neck Pain. A Pilot Randomized Controlled Trial
Status: RECRUITING
Conditions: Neck Pain|Temporomandibular Disorder
Interventions: OTHER: Clinical reasoning based physiotherapy + cervical movement control training|OTHER: Clinical reasoning based physiotherapy + orofacial movement control training|OTHER: Clinical reasoning based physiotherapy + standard exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled, In Vivo, Pilot Study to Assess the Recovery and Survival of Radiolabeled Autologous INTERCEPT Treated 7-Day Stored Apheresis Platelet Components in 35% Plasma and 65% InterSol and 7-Day Stored Apheresis Platelet Components in 100% Plasma
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: INTERCEPT treated platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Internet-Based Nutrition Education Program in Preventing Cancer in Participants of Health Maintenance Organizations
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: behavioral dietary intervention|DIETARY_SUPPLEMENT: dietary intervention|OTHER: educational intervention|OTHER: internet-based intervention|OTHER: preventative dietary intervention|PROCEDURE: evaluation of cancer risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE|Primary Purpose:
Clinical trial: Anterior Lens Capsule as a Spacer in the Deep Sclerectomy _ Phacoemulsification
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma|Cataract
Interventions: PROCEDURE: Non-penetrating deep sclerectomy and phacoemulsification and autotransplantation of anterior lens capsule|PROCEDURE: Non-penetrating deep sclerectomy and phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis
Status: NOT_YET_RECRUITING
Conditions: Mucositis Oral
Interventions: DRUG: glutamine combined with thalidomide|DRUG: glutamine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Resistant Hypertension by Renal Denervation in China
Status: TERMINATED
Conditions: Medication-resistant Hypertension
Interventions: DEVICE: Percutaneous renal denervation with the Vessix™ Renal Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Swallowing Training Combined With Game-based Biofeedback in Post-stroke Dysphagia
Status: UNKNOWN
Conditions: Dysphagia
Interventions: DEVICE: Game-based swallow biofeedback|BEHAVIORAL: Swallow training without biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: DRUG: RRx-001 + WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levocetirizine in the Treatment of Nasal Obstruction Due to Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Levocetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Active Deresuscitation After Resuscitation:
Status: NOT_YET_RECRUITING
Conditions: Fluid Overload|Critical Illness|Sepsis|ARDS|Trauma
Interventions: DRUG: Furosemide Injection|DRUG: Metolazone Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Catheter for Open Heart Surgery
Status: WITHDRAWN
Conditions: Post Operative Analgesia
Interventions: DRUG: Ropivacaine 0.2%|DRUG: saline 09%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Immunologic Antiviral Therapy With Omalizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: BIOLOGICAL: Omalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ureteral Stent Study
Status: COMPLETED
Conditions: Urolithiasis
Interventions: DEVICE: Cook Sof-Flex® Double Pigtail Ureteral Stent coextruded with doxazosin|DEVICE: Cook Sof-Flex® Double Pigtail Ureteral Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section
Status: UNKNOWN
Conditions: Transient Tachypnea of the Newborn|Neonatal Respiratory Distress
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparing Parent-Implemented Interventions for Toddlers With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: BEHAVIORAL: Early Social Interaction Project- PII|BEHAVIORAL: Early Social Interaction Project- IES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Rectus Sheath Block on Quality of Recovery in Single Port Laparoscopic Adnexal Surgery
Status: NOT_YET_RECRUITING
Conditions: Single Port Laparoscopic Adnexal Surgery
Interventions: DRUG: Ultrasound guided rectus sheath block with dexmedetomidine|DRUG: Ultrasound guided rectus sheath block with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE