pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Probiotics in the Treatment of NAFLD
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis|Fatty Liver, Nonalcoholic|NAFLD
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of AQUAVAN® Injection for Sedation During Cardiac Catheterization
Status: COMPLETED
Conditions: Angioplasty|Coronary Catheterization
Interventions: DRUG: fospropofol disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BREntuximab Vedotin in SEcond LIne Therapy BEfore Transplant
Status: RECRUITING
Conditions: Hodgkin Lymphoma, Adult
Interventions: DRUG: Induction with Brentuximab vedotin (BV)|DRUG: Induction without Brentuximab Vedotin|DRUG: Consolidation with Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
Status: COMPLETED
Conditions: Bioequivalence|Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin/Metformin HCl 50/500 mg extended release film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Helium:Oxygen Noninvasive Positive Pressure Ventilation in Patients Exposed to Sulfur Mustard
Status: COMPLETED
Conditions: Bronchiolitis|Chronic Bronchitis
Interventions: DRUG: helium:oxygen mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: L-DOPS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride Pilot Study (SDF)
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Silver Diamine Fluoride 38%|DEVICE: Group 2 (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Berberis Vulgaris Consumption and Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure|Cardiovascular Risk Factor|Lipid Profile
Interventions: DIETARY_SUPPLEMENT: berberis vulgaris=barberry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assisted Exercise in Obese Endometrial Cancer Patients
Status: COMPLETED
Conditions: Stage I Endometrial Adenocarcinoma|Uterine Cancer|Obesity
Interventions: BEHAVIORAL: Exercise on stationary recumbent exercise cycle|BEHAVIORAL: Health Education|BEHAVIORAL: Questionnaires|PROCEDURE: Neuroimaging|PROCEDURE: Genetic and Biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: UTAA09 Injection in the Treatment of Relapsed/Refractory Hematolymphatic Malignancies.
Status: NOT_YET_RECRUITING
Conditions: CD19-positive Relapsed or Refractory B-cell Malignancies
Interventions: BIOLOGICAL: UTAA09 cells for infusion|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Anti-Viral Vaccine for Healthy Elderly Adults
Status: COMPLETED
Conditions: Virus Diseases|Pneumonia|COVID-19 Respiratory Infection|RSV Pneumonia|Influenza, Human|ARDS, Human
Interventions: DRUG: AlloStim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 3-Way Crossover Study to Evaluate the Pharmacokinetics in Participants After Dosing With Pegilodecakin (LY3500518)
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: BIOLOGICAL: Pegilodecakin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atelectasis Formation: Role of Positive Pressure Breathing, Hyperoxia, and Hypobaria
Status: UNKNOWN
Conditions: Pulmonary Atelectasis
Interventions: OTHER: +Gz accelerations and positive pressure breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood Gene Expression Signature in Patients Diagnosed With Probable Alzheimer's Disease Compared to Patients Suffering From Other Types of Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia
Interventions: DEVICE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Ch-mAb7F9 for Methamphetamine Abuse
Status: COMPLETED
Conditions: Methamphetamine Abuse
Interventions: BIOLOGICAL: normal saline|BIOLOGICAL: ch-mAb7f9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Remote Ischemic Preconditioning for Prevention of Contrast Medium-induced Nephropathy in High Risk Patients
Status: COMPLETED
Conditions: Nephropathy
Interventions: OTHER: Remote Ischemic Preconditioning (RIPC)|OTHER: SHAM Remote Ischemic Preconditioning (SHAM RIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Advanced Hemodynamic Monitoring for Goal-directed Hemodynamic Management During Radical Cystectomy
Status: UNKNOWN
Conditions: Radical Cystectomy|Perioperative Complications|Hemodynamic Monitoring
Interventions: OTHER: Increasing oxygen delivery .
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses
Status: NOT_YET_RECRUITING
Conditions: Twin to Twin Transfusion Syndrome
Interventions: DEVICE: Curved KARL STORZ fetoscope|DEVICE: Conventional Scopes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telenursing and Remote Monitoring in Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Usual Care of IPF|OTHER: Telenursing|OTHER: Telenursing and Remote Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neuroimaging of Dystonia
Status: COMPLETED
Conditions: Primary Cervical Dystonia|DYT 1 Dystonia
Interventions: DRUG: Primary Cervical Dystonia (Trihexyphenidyl)|OTHER: Controls Primary Cervical Dystonia (Trihexyphenidyl)|OTHER: DYT 1 Dystonia (Healthy Control)|OTHER: DYT 1 Dystonia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetic-Dependent Cardiovascular Response to PPAR-Alpha Agonist Fenofibrate
Status: RECRUITING
Conditions: Type 2 Diabetes|Cardiovascular Diseases|Pharmacogenomic Drug Interaction
Interventions: DRUG: Fenofibrate 145 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Periodontal Disease and Diabetes Mellitus Interrelationship Among Adult Malaysians
Status: COMPLETED
Conditions: Chronic Periodontitis|Type 2 Diabetes
Interventions: PROCEDURE: Nonsurgical periodontal therapy|PROCEDURE: Oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population
Status: COMPLETED
Conditions: Disuse Atrophy
Interventions: DIETARY_SUPPLEMENT: Profile Perform|OTHER: Lower Limb Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric
Status: COMPLETED
Conditions: Menopausal Syndrome|Hot Flashes
Interventions: DRUG: Sulpiride use|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicomponent Technology Supported Care Delivery for Older Patients With Hematologic Malignancies (The M-Tech Study)
Status: WITHDRAWN
Conditions: Cancer
Interventions: BEHAVIORAL: M-Tech|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Triple-Negative Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Anti-HER2/HER3 Dendritic Cell Vaccine|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of VSL#3 on Bone Mineral Density in Postmenopausal Women
Status: TERMINATED
Conditions: Menopausal Osteoporosis
Interventions: DRUG: VSL#3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of iLTS and LMA Fastrach in a Simulated Airway.
Status: COMPLETED
Conditions: Ventilation Therapy; Complications
Interventions: DEVICE: Time to ventilation with the iLTS|DEVICE: Time to ventilation with the Fastrach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Education Via Hybrid Simulation Method in the Antenatal Period on Postpartum Breastfeeding
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Breastfeeding education using hybrid simulation method|BEHAVIORAL: Routine verbal breastfeeding education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Fibrin Sealant Grifols Evaluated as an Adjunct to Hemostasis
Status: COMPLETED
Conditions: Target Bleeding Site During Peripheral Vascular Surgery
Interventions: BIOLOGICAL: FS Grifols|BIOLOGICAL: FS Grifols|PROCEDURE: Manual Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clonidine and Morphine in Caudal Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Clonidine|DRUG: Morphine|DRUG: Bupivacaine plus clonidine and morphine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Low dose tenecteplase|DRUG: High dose tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fiberoptic Bronchoscopic Intubation Between Silicone and Polyvinylchloride Double Lumen Tube.
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: DEVICE: Fibreoptic intubation with silicone double lumen tube|DEVICE: Fibreoptic intubation with PVC double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Web-based Nursing Intervention to Promote Physical Activity Among Older Adults With Coronary Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Older Adults|Web-based Intervention|Nursing|Healthy Lifestyle Habits
Interventions: BEHAVIORAL: Web-based nursing intervention : Ch@ngeons Ensemble
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cohort Prospective Study of Children With Head and Neck Cystic Malformation Who Are Treated With Intracystic OK432
Status: UNKNOWN
Conditions: CYSTIC MALFORMATION
Interventions: DRUG: Intracystic injection of OK432 under US guiding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Oral Cancer Screening Among HIV Infected Individuals
Status: COMPLETED
Conditions: Malignant Neoplasms of Mesothelial and Soft Tissue|Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Screening Interview|DEVICE: Carbon Monoxide Test|BEHAVIORAL: Self-Help Materials|PROCEDURE: Visual Oral Screening Examination|PROCEDURE: Direct Fluorescent Oral Visualization Examination|PROCEDURE: Oral Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety of TT-00420 (Tinengotinib) Monotherapy in Patients With Advanced Solid Tumors and Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors|Triple Negative Breast Cancer
Interventions: DRUG: TT-00420
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors
Status: RECRUITING
Conditions: Colorectal Cancer|Solid Tumors
Interventions: DRUG: Revumenib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tolerability to Agavins and Impact on Host-gut Microbiota-metabolism Interactions Modulation
Status: COMPLETED
Conditions: Obesity|Healthy
Interventions: DIETARY_SUPPLEMENT: Agavins (prebiotic fiber)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RECOVER-ENERGIZE Platform Protocol
Status: RECRUITING
Conditions: Long COVID|Long Covid19|Long Covid-19
Interventions: BEHAVIORAL: Personalized Cardiopulmonary Rehabilitation|BEHAVIORAL: Structured Pacing|OTHER: Education|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring Brain Activity in Relation to Sensory Arm Impairments in the Early Stages of Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Electroencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/ Primary Peritoneal Cancer Patients Receiving Chemotherapy: A Feasibility Study
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction
Status: RECRUITING
Conditions: Ischemic Heart Failure
Interventions: DEVICE: Autologous bone marrow mononuclear cells processed / delivered using the CardiAMP cell therapy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects
Status: COMPLETED
Conditions: Phase 1
Interventions: DRUG: GV101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interval Versus Continuous Exercise During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related|Glucose, Low Blood|Fetal Heart Rate or Rhythm Abnormality Affecting Fetus|Fetal Blood Flow
Interventions: OTHER: High intensity Interval Training|OTHER: Moderate Intensity Continuous Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immature Granulocyte Count and Delta Neutrophil Index Factors for Axillary Metastasis of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer Invasive
Interventions: PROCEDURE: Mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexamethasone, Can it Replace Ketoprofen in the Strategy of Intraoperative Multimodal Analgesia in Paediatric Surgery ? A Prospective Randomized Double-blinded Study. DEXA OP
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone 0.2 mg/kg|DRUG: Dexamethasone 0.4 mg/kg|DRUG: Ketoprofen 1 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Chhinnavahni Kashaya Vati along with Agnimantha Kwatha|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders
Status: COMPLETED
Conditions: Major Depressive Disorder|Persistent Depressive Disorder|Posttraumatic Stress Disorder|Panic Disorder|Social Phobia|Specific Phobia|Generalized Anxiety Disorder|Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Transdiagnostic Behavior Therapy|BEHAVIORAL: Behavioral Activation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Vitamin D Deficiency
Interventions: DRUG: Vitamin D2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of NfL and GFAP Levels, Atrophy of the Macula GCC by OCT and Whole Brain Atrophy by MRI to Predict Evolution of Neurological Disability in MS Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: Brain MRI|DIAGNOSTIC_TEST: Spinal Cord MRI|DIAGNOSTIC_TEST: Retinal imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Home-base Exercise With Conical-PEP Device on Physical Performance and Quality of Life in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: A non-re-breathing face mask with conical-PEP device|OTHER: A home-base exercise program|OTHER: Health education|OTHER: ฺBreathing strategies for self secretion clearance|DRUG: The medication following the COPD GOLD guidelines (2015)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Efficacy, Safety, And Pharmacokinetics Of The Port Delivery System With Ranibizumab In Chinese Patients With Neovascular Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age Related Macular Degeneration|nAMD
Interventions: DEVICE: PDS with ranibizumab (100 mg/mL)|DRUG: Ranibizumab (10 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stepping Together for Children After Trauma, Norway
Status: RECRUITING
Conditions: PTSD|Sleep Disorder|Depressive Symptoms|Quality of Life
Interventions: BEHAVIORAL: Stepping Together for Children after Trauma (ST-CT)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Stereotactic Radiosurgery For Liver Malignancies
Status: COMPLETED
Conditions: Cholangiocarcinoma|Liver Cancer|Adenocarcinoma
Interventions: PROCEDURE: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line Pazopanib Renal Cell Carcinoma (RCC) Study. CTRIAL-IE (ICORG) 10-01, V5
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0349 Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone With or Without Oblimersen in Treating Patients With Advanced Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Contiguous Stage II Adult Diffuse Large Cell Lymphoma|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma
Interventions: BIOLOGICAL: oblimersen sodium|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: vincristine sulfate|DRUG: prednisone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of Incisional Hernia on Muscular and Postural Function
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: DIAGNOSTIC_TEST: Dynamometric tension assessment|DIAGNOSTIC_TEST: Postural balance|DIAGNOSTIC_TEST: Assessment of the hernia defect size|DIAGNOSTIC_TEST: Physical activity of patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate
Status: RECRUITING
Conditions: Neurotrophic Ulcer|Neurotrophic Keratitis|Neurotrophic Corneal Ulcer|Neurotrophic Keratoconjunctivitis
Interventions: DRUG: Cenegermin-Bkbj 0.002% Ophthalmic Solution [OXERVATE]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Pharmacodynamics Assessment of Drug Eritromax Compared to Eprex in Healthy Subjects.
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Eritromax|DRUG: Eprex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Artificial Intelligence With Balloon Mucosal Exposure Device for Polyp Detection in Screening Individuals
Status: COMPLETED
Conditions: Polyp of Colon
Interventions: DEVICE: G-EYE 760 R endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot of Virtual Health Coaching Utilizing Lifestyle for Under-Resourced Patients With Type II Diabetes
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: Phone-Based Health Coaching Utilizing Lifestyle Action Plans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Intrauterine Lidocaine and Naproxen for Pain Control With Intrauterine Device Insertion
Status: COMPLETED
Conditions: Contraception|Pain
Interventions: DRUG: Naproxen|DRUG: Lidocaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aliskiren/Amlodipine Versus Amlodipine Monotherapy on Ankle-foot Volume in Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: aliskiren/amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Shapes for Intubation With Videolaryngoscope
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: J shaped stylet used for endotracheal intubation|DEVICE: 60-degrees stylet used for endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Locally Advanced Pancreatic Cancer
Interventions: DRUG: Pembrolizumab|DEVICE: Irreversible Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Insoles in Patients With Rheumatoid Arthritis: Randomized Controlled Trial.
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Custom Insoles|DEVICE: Standardized insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study for Development and Use of Neurofeedback-trainings for Patients Suffering From Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DEVICE: Tomographic Neurofeedback|DEVICE: Non Tomographic Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Atorvastatin and Anakinra in Children With Coronary Artery Abnormalities Secondary to Kawasaki Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Kawasaki Disease
Interventions: DRUG: Atorvastatin and anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma
Status: UNKNOWN
Conditions: Resectable Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Metformin Hydrochloride 500Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based vs In-person Personalized Feedback Intervention for Comorbid Substance Use and Disordered Gambling
Status: COMPLETED
Conditions: Gambling|Alcohol Consumption|Cannabis
Interventions: BEHAVIORAL: Personalized Feedback Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery
Status: NOT_YET_RECRUITING
Conditions: Glaucoma Congenital
Interventions: PROCEDURE: single-site rigid probe viscotrabeculotomy (VT)|PROCEDURE: two-site rigid probe viscotrabeculotomy (VT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Sensitization Test (Modified Draize-95 Test)
Status: COMPLETED
Conditions: Skin Sensitisation
Interventions: DEVICE: NON-STERILE, POWDER FREE NITRILE EXAMINATION GLOVES, LOW DERMATITIS POTENTIAL, TESTED FOR USE WITH CHEMOTHERAPY DRUGS - BLUE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: AZD2693|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)
Status: COMPLETED
Conditions: Coronary Atherosclerosis|Coronary Artery Calcification|Coronary Stenosis
Interventions: DIETARY_SUPPLEMENT: Aged garlic extract and Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Insulin Action in Psoriasis Pathogenesis
Status: RECRUITING
Conditions: Psoriasis|Plaque Psoriasis|Insulin Resistance|PreDiabetes|Overweight and Obesity
Interventions: DIAGNOSTIC_TEST: Oral glucose tolerance test (OGTT)|PROCEDURE: Skin punch biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The SAD Study - SLEEP, ANXIETY & DEPRESSION Study A Prospective Cohort Study
Status: UNKNOWN
Conditions: Patients With Anxiety and Depression, Who Have|Obstructive Sleep Apnoea|COPD
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-Acting Treatment in Adolescents (LATA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hiv|HIV Infections|HIV-1-infection|Paediatric Human Immunodeficiency Virus Infection
Interventions: DRUG: Cabotegravir, Rilpivirine Drug Combination|DRUG: TLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Duloxetine on Pain Relief After Total Knee Arthroplasty in Central Sensitization Patient
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Duloxetine|DRUG: celecoxib, Pregabalin, acetaminophen/tramadol, oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|PTSD
Interventions: BEHAVIORAL: Cognitive Processing Therapy (cognitive only version; CPT-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: V+PSF-M for Tobacco Cessation in HIV Care in India
Status: RECRUITING
Conditions: Human Immunodeficiency Virus|Smoking Cessation|Smoking, Tobacco
Interventions: DRUG: Varenicline|BEHAVIORAL: Positively Smoke Free Mobile (PSF-M)|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis
Status: RECRUITING
Conditions: Severe Aplastic Anemia (SAA)|Hypo-Plastic Myelodysplastic Syndrome (MDS)|Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Cyclophosphamide|OTHER: Peripheral Blood Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite
Status: COMPLETED
Conditions: Malignant Mesothelioma|Pulmonary Complications
Interventions: GENETIC: microarray analysis|GENETIC: protein expression analysis|GENETIC: proteomic profiling|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Investigate The Effect Of Food On The Pharmacokinetics Of PH-797804
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Manual Therapy After Ankle/Hindfoot Fractures
Status: COMPLETED
Conditions: Ankle Fracture|Calcaneus Fracture|Talus Fracture|Pilon Fracture
Interventions: OTHER: Manual Therapy Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Modified Gegen Qinlian Decoction for Ulcerative Colitis With Damp-heat Syndrome
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Modified Gegen Qinlian Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Combo Immuno and Target Therapy (SECOMBIT) Study
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: LGX818|DRUG: MEK162|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplant for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Cyclophosphamide + Mesna|DRUG: Melphalan|BIOLOGICAL: Granulocyte-colony stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paxil CR Bioequivalence Study Brazil - Fed Administration
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Paxil CR 25 mg manufactured by SmithKline Beecham (Cork) Limited - Cidra - Puerto Rico|DRUG: Paxil CR 25 mg manufactured by GlaxoSmithKline Inc. - Mississauga - Canada
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tiotropium (18 Mcg) Once Daily Via the HandiHaler® in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)
Status: COMPLETED
Conditions: Familial Chylomicronemia Syndrome|Lipoprotein Lipase Deficiency|Hyperlipoproteinemia Type 1
Interventions: DRUG: AKCEA-ANGPTL3-LRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Liposome and Cisplatin as First-line Chemotherapy in Patients With Metastatic Esophageal Cancer
Status: WITHDRAWN
Conditions: Esophageal Cancer
Interventions: DRUG: Paclitaxel liposome|DRUG: Cisplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolvaptan-Octreotide LAR Combination in ADPKD
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Tolvaptan|DRUG: Octreotide LAR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fimasartan for Modification of Atheroma Vulnerability in DEFERred Coronary Disease (FIMA-DEFER)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Fimasartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cholecalciferol in Pre-frail Elderly
Status: COMPLETED
Conditions: Pre-frail Elderly
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three-Year Clinical Evaluation of Class II Posterior Composite Restorations
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Aelite Flo|PROCEDURE: x-tra base
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Delta-Shaped and Billroth II After TLDG
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Delta-shaped anastomosis|PROCEDURE: Billroth II anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Alter-G Training on Glycemic Control and Quality of Life in Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy
Interventions: OTHER: weight off-loading aerobic exercise training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: BMS-986165|DRUG: Placebo|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea, Arrhythmias and Cardiac Reverse Remodeling in Heart Failure Patients
Status: WITHDRAWN
Conditions: Sleep Breathing Disorders in the Responders to Cardiac Resynchronisation Therapy (CRT)
Interventions: OTHER: Echocardiographic, polygraphy, electrocardiography measurements and sleep questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating Sirolimus in Kidney Transplant Recipients.
Status: COMPLETED
Conditions: Kidney Failure|Graft vs Host Disease
Interventions: DRUG: Cyclosporine|DRUG: Steroids|DRUG: Rapamune (Sirolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Exposure to Inclusive Virtual Art Decrease Pain and Social Disconnection Among Individuals Living With Chronic Pain?
Status: COMPLETED
Conditions: Chronic Pain|Social Disconnection
Interventions: BEHAVIORAL: Artwork present|BEHAVIORAL: Artwork absent|BEHAVIORAL: Social connection high|BEHAVIORAL: Social connection low
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Drugs on Stress Memories
Status: RECRUITING
Conditions: Delta-9-tetrahydrocannabinol (THC)|Stress
Interventions: DRUG: delta-9-tetrahydrocannabinol (THC) (5)|DRUG: Placebo|DRUG: delta-9-tetrahydrocannabinol (THC) (10)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Actinium Ac 225-DOTA-anti-CEA Monoclonal Antibody M5A|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategic Use of Big Data in Spine Surgery - Testing Digital Prediction of Outcome in Clinical Praxis
Status: RECRUITING
Conditions: Constriction, Pathologic|Spine Degeneration|Surgery|Radiculopathy
Interventions: OTHER: Dialogue support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma
Status: RECRUITING
Conditions: Retroperitoneal Sarcoma
Interventions: DRUG: Abemaciclib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Effects of Natural and Interesterified Fats Margarine on Insulin Sensitivity and Selected Markers of Cardiovascular Diseases (CVD)
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Palm Olein|OTHER: IE Palm olein|OTHER: IE soybean oil-based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: metformin 1500 mg|DRUG: myoinositol 1500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bavituximab Repeat-Dose Trial in Patients Co-Infected With Chronic Hepatitis C Virus and Human Immunodeficiency Virus
Status: COMPLETED
Conditions: Hepatitis C Virus|Hiv Infections
Interventions: DRUG: bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Patient Generated Family Health History From Varied Electronic Health Record (EHR) Entry Portals
Status: COMPLETED
Conditions: Family Characteristics|Health Status|Family Research
Interventions: OTHER: Electronic Health Portals for collecting Family History data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I, Multi-Center, Open-Label, Dose Escalation Study of HuLuc63 in Subjects With Advanced Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: HuLuc63
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemadsorption During and After Cardiopulmonary Bypass to Modulate the Inflammatory Response
Status: UNKNOWN
Conditions: Inflammatory Response|Chronic Renal Disease|Cardiac Surgery
Interventions: DEVICE: CytoSorb|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Physiotherapy, Nutritional Supplement and Anabolic Steroids in Rehabilitation of Patients With Hip Fracture.
Status: COMPLETED
Conditions: Hip Fractures
Interventions: DRUG: Nandrolone Decanoate|DIETARY_SUPPLEMENT: Protein-rich nutritional supplement|OTHER: Physical therapy|DRUG: Sodium Chloride 9mg/ml Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supportive Intervention Programs Study
Status: COMPLETED
Conditions: Fatigue|Nausea and Vomiting|Pain|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage I-IVB Colon Cancer|Stage I-IVB Rectal Cancer
Interventions: PROCEDURE: Yoga therapy|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis|OTHER: assessment of therapy complications|PROCEDURE: management of therapy complications|OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Scoliotic Changes in Children at Increased Risk for Scoliosis Development
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis|22q11.2 Deletion Syndrome
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Scolioscan|DIAGNOSTIC_TEST: Skeletal maturity assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of the Safety and Efficacy of the Addition of Ramucirumab to Nab-paclitaxel in Previously Treated Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: ramucirumab|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of One-shade Universal Dental Resin Composite as Posterior Restoration
Status: COMPLETED
Conditions: Carious Teeth
Interventions: OTHER: US Public Health Service "USPSH" criteria for assessment of success of resin composite restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT