pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Resuvastatin Treatment for Symptomatic Middle Cerebral Artery Stenosis Based on High-resolution Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Intracranial Arterial Stenosis
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic Coordinated Reset (CR®) Neuromodulation for the Treatment of Chronic Tonal Tinnitus ("RESET Real Life")
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: ANM T30 CR®-System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Reduction in Pain After Laparoscopic Hernia Repair With Mesh Soaked in Bupivacaine Solution
Status: UNKNOWN
Conditions: Abdominal Wall Defect
Interventions: DRUG: Bupivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Prevention and Treatment of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer
Status: RECRUITING
Conditions: Malignant Tumor of Head and/or Neck|Radiotherapy; Complications
Interventions: DEVICE: verum acupuncture|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Describe The Safety, Tolerability, And Immunogenicity Of Bivalent Rlp2086 Vaccine In Laboratory Workers ≥18 To ≤65 Years Of Age
Status: COMPLETED
Conditions: Meningitis, Meningococcal, Serogroup B
Interventions: BIOLOGICAL: rLP2086
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Measuring Adherence to Home Shoulder Physiotherapy With Artificial Intelligence
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Pathology
Interventions: DEVICE: Smart Physiotherapy Activity Recognition System (SPARS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time NIRS Neurofeedback Regulating Brain Cognitive Function in Obese Individuals
Status: UNKNOWN
Conditions: Obesity|Neurofeedback
Interventions: BEHAVIORAL: NIRS neurofeedback|BEHAVIORAL: Sham NIRS neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between PECS BLOCK 2 vs ESP BLOCK in Ocnologic Breast Surgery
Status: UNKNOWN
Conditions: Breast Cancer|Breast Neoplasms|Breast Carcinoma
Interventions: PROCEDURE: PECS BLOCK 2|PROCEDURE: ESP BLOCK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Correlation of Serum Adalimumab Levels at an Administration of 40 mg Weekly vs 80 mg Every Two Weeks
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonmyeloablative Allogeneic Transplant
Status: COMPLETED
Conditions: Aplastic Anemia|Paroxysmal Nocturnal Hemoglobinuria|Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Myelodysplastic Syndrome|Chronic Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma|Multiple Myeloma|Waldenstrom Macroglobulinemia|Breast Cancer|Renal Cell Carcinoma|Melanoma|Sarcoma|Ovarian Cancer|Thymoma
Interventions: PROCEDURE: Nonmyeloablative Allogeneic Transplant|PROCEDURE: Nonmyeloablative Allogeneic Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Field Magnetic Stimulation Treatment for Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression|Bipolar Disorder|Depression
Interventions: DEVICE: Echo-Planar Magnetic Resonance Imaging (EP-MRSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
Status: COMPLETED
Conditions: Myoma|Uterine Bleeding, Dysfunctional|Uterine Bleeding Heavy|Dysmenorrhea|Endometrium Hyperplasia
Interventions: DIAGNOSTIC_TEST: Transvaginal ultrasonographic examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS
Status: NOT_YET_RECRUITING
Conditions: Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation Between Adverse Reactions to Food, Physical Performance and Health in a Mediterranean Population
Status: RECRUITING
Conditions: Food Allergy|Food Intolerance|Adverse Reaction to Food
Interventions: OTHER: Allergen-specific substitute diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Multiple Occupational Therapies On Functional Remission And Subjective Recovery For Schizophrenia
Status: COMPLETED
Conditions: Occupational Therapy|Schizophrenia|Remission|Well-Being, Psychological
Interventions: BEHAVIORAL: occupational therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome
Status: RECRUITING
Conditions: Abdominal Hernia
Interventions: PROCEDURE: Open Hernia surgery|PROCEDURE: Robotic Hernia surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidants and Zinc Improving Minimal Hepatic Encephalopathy In Truck Drivers; a Pilot Study
Status: COMPLETED
Conditions: Minimal Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: 175 mg zinc gluconate, 50000 IU vitamin A, 500 mg vitamin C and 100 mg vitamin E once daily plus lactulose; dose 30-60 ml/day for 3 months|DIETARY_SUPPLEMENT: Lactulose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Obturator Nerve Block for Total Knee Replacement (TKR)
Status: UNKNOWN
Conditions: Total Knee Replacement|Surgery
Interventions: OTHER: Sciatic, femoral, obturator nerve blocks|OTHER: Sciatic nerve block, posterior lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label, Dose-Regimen Study Evaluating Etanercept 50 mg Once-Weekly In Japanese Subjects With RA
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Educational Program Associated With Exercises (EDEX) Before Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Educational and exercise program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Recurrent or Progressive Meningiomas With the Radiolabelled Somatostatin Antagonist 177Lu-satoreotide
Status: RECRUITING
Conditions: Meningioma
Interventions: DRUG: 177Lu-DOTA-JR11 (Phase 0); Cycle 1 and Cycle 2 (cross-over)|DRUG: 177Lu-DOTATOC (Phase 0); Cycle 1 and Cycle 2 (cross-over), Cycle 3 and 4|DRUG: 177Lu-DOTA-JR11 (Phase I/II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From Protease Inhibitor (PI) to Etravirine in HIV-1 Infected Subjects With Viremia Suppression
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Etravirine 400 mg dissolved in water every 24 hours|DRUG: Continue with the same antiretroviral regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Same Day Bidirectional Endoscopies - Does the Sequence of Procedures or Choice of Insufflator Matter?
Status: COMPLETED
Conditions: Anemia|Colon Polyps
Interventions: DEVICE: Carbon dioxide insufflation|DEVICE: room air insufflation|PROCEDURE: EGD (Esophagogastroduodenoscopy) before Colonoscopy|PROCEDURE: Colonoscopy before EGD (Esophagogastroduodenoscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Vildagliptin as Add-on Therapy to Sulfonylurea in Patients With Type 2 Diabetes Inadequately Controlled With Sulfonylurea Monotherapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET)
Status: COMPLETED
Conditions: High Risk Polycythemia Vera|High Risk Essential Thrombocythemia
Interventions: DRUG: PEGASYS|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Functional Imaging in Monogenic PD.
Status: RECRUITING
Conditions: Parkinson Disease|Nervous System Disorder|Neurodegenerative Diseases|Neurodegenerative Disease, Hereditary|Parkinson's
Interventions: OTHER: Positron Emission Tomography (PET) scan using DASB tracer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate the Ingested, Space Occupying Hydrogel Capsules for Simple Obesity Treatment
Status: NOT_YET_RECRUITING
Conditions: Simple Obesity
Interventions: DEVICE: Ingested, Space Occupying hydrogel capsules|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoadsorption and Immunoglobulin Substitution for Heart Failure After Myocardial Infarction
Status: WITHDRAWN
Conditions: Heart Failure|Coronary Heart Disease
Interventions: DEVICE: Immunoadsorption / Immunoglobulin substitution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke|CYP2C19 Polymorphism
Interventions: OTHER: CYP2C19 Genotype
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Local and Systemic Tolerability, and Pharmacokinetics of Multiple-Dose Topical Administration of PF-07038124 in Japanese Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07038124 or vehicle|DRUG: PF-07038124 or vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting and Exercise-induced Changes in Human Skeletal Muscle
Status: COMPLETED
Conditions: Skeletal Muscle Energetics
Interventions: OTHER: FAST+EX|OTHER: FAST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) Infection
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C, Chronic|Chronic Hepatitis C|Hepatitis C Virus Infection|HCV Infection
Interventions: DRUG: AT-527|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ERIG Injection on Day 7 After First Dose of Rabies Vaccination to Rabies Immune Response
Status: UNKNOWN
Conditions: Rabies
Interventions: BIOLOGICAL: Equine rabies immunoglobulin injection on day 7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basal Analog Study - Comparison of Lantus or Levemir With NPH Insulin From T1DM Diagnosis
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: NPH insulin|DRUG: Glargine|DRUG: Detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Vitamin D Analogue vs Placebo on p-NT-proBNP in Patients With Type 1 DM and Diabetic Nephropathy
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetic Nephropathy
Interventions: DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: POC-MD MRI-based Trial in Relapsing-remitting Multiple Scler
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis|RRMS
Interventions: DRUG: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Atezolizumab|DRUG: Placebo|DRUG: Gemcitabine|DRUG: Capecitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Philani Mobile Video Intervention for Exclusive Breastfeeding (MOVIE) Study
Status: COMPLETED
Conditions: Exclusive Breastfeeding|Infant Feeding Practices
Interventions: BEHAVIORAL: Philani Intervention Model+MOVIE (PIM+M)|BEHAVIORAL: Philani Intervention Model (PIM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wearable Bioimpedance Analyzer for Tracking Body Composition Changes
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Knee Osteoarthritis
Interventions: DEVICE: InBody Band 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Trial of Methyl Aminolevulinate Plus Aktilite in Facial Photodamage
Status: COMPLETED
Conditions: Skin Aging
Interventions: OTHER: Moisturizer|DRUG: Methyl Aminolevulinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgia
Status: TERMINATED
Conditions: Shingles|Herpes Zoster|Postherpetic Neuralgia
Interventions: DRUG: FV-100|DRUG: valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Creatine as a New Therapeutic Strategy in Depression
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of Low Dose Chest CT for Virtual Bronchoscopy Navigation - Human Study.
Status: UNKNOWN
Conditions: Bronchoscopy
Interventions: DIAGNOSTIC_TEST: Chest CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Prevalence of Germs Slow Growth in the Intervertebral Disc (IVD) During Spinal Surgery
Status: COMPLETED
Conditions: Prevalence of Germs|Spinal Surgery|Anterior Disc Disease|Modic 1
Interventions: OTHER: Bacteriological analysis of disc
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Dry Needling (DNHS Technique) in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke|Spasticity
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate|DRUG: Amprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metvix Photodynamic Therapy (PDT) Versus Cryotherapy in Participants With Primary Superficial Basal Cell Carcinoma
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: Metvix® cream|PROCEDURE: Hand held liquid nitrogen spray cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging
Status: TERMINATED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension|Normal Tension Glaucoma
Interventions: DEVICE: 7-Tesla MRI|OTHER: Optical Coherence Tomography|OTHER: Heidelberg Retina Tomography|OTHER: Scanning Laser Polarimetry|OTHER: Humphrey Perimetry|OTHER: Applanation Tonometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VeDOlizumab PERsistence in IBD Patients After Switching From Intravenous to Subcutaneous Administration : a Real-life Multicenter Study (DOPER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Subcutaneous vedolizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI4893 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Staphylococcus Aureus
Interventions: DRUG: Placebo|DRUG: MEDI4893
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Eltrombopag Used in Thrombocytopenia After Comsolidation Therapy in AML
Status: UNKNOWN
Conditions: Eltrombopag|Thrombocytopenia|Acute Myeloid Leukemia
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: chlorambucil|DRUG: clarithromycin|DRUG: omeprazole|DRUG: tinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: NP202|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Nutritional Health Literacy With Multi-component Nutrition Education Given to University Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: OTHER: multi-component nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Air Pollution to Lower Blood Pressure
Status: UNKNOWN
Conditions: Mild Hypertension|Air Pollution Exposure
Interventions: DEVICE: Portable Air Cleaner with a HEPA Filter|DEVICE: Portable Air Cleaner without a HEPA Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nucleotides and B Vitamins in the Treatment of Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Nucleotides + B12|DRUG: B Vitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of HCQ Plus DEX in ANA Positive ITP
Status: RECRUITING
Conditions: Immune Thrombocytopenia With Positive ANA Antibodies
Interventions: DRUG: Hydroxychloroquine Oral Tablet|DRUG: Dexamethasone oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Enzalutamide Re-treatment in Metastatic Castration-resistant Prostate Cancer After Docetaxel and/or Cabazitaxel Treatment
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Rivipansel With rHuPH20 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivipansel|DRUG: Placebo|DRUG: Rivipansel|DRUG: Rivipansel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Somatic-psychosocial Care Concept for Oncologic Patients Undergoing Hematopoietic Stem Cell Transplantation (HSCT)
Status: COMPLETED
Conditions: Oral Mucositis|Malnutrition
Interventions: BEHAVIORAL: Control Group|BEHAVIORAL: SCION-HSCT program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Progressive Relaxation Exercises on Physiological Parameters, Pain and Anxiety After Cesarean Section
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: OTHER: Progressive relaxation exercises will be applied.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Pharmacokinetics and Safety of INX-08189 Administered With VictrelisTM in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: INX-08189 50 mg QD X 5 days|DRUG: INX-08189 / Victrelis 800 mg TID X three days|DRUG: Victrelis 800 mg TID x 3 days|DRUG: Victrelis 800 mg TID with INX-08189 50 mg QD|DRUG: Placebo with Victrelis 800 mg|DRUG: Cohort 2: Victrelis 800 mg with Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of SPIL1033 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SPIL1033|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Assess the Visual Performance and Comfort of Hanita G4 Multifocal Soft Contact Lenses for Presbyopia at Normal Daily Routine Use
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: G4 Multifocal soft contact lens with a 54% water content for presbyopia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Listening to Low Tones on Motor Function in Children With CP
Status: COMPLETED
Conditions: Cerebral Palsy|Hypertonia
Interventions: BEHAVIORAL: listening to music / stories via stereophonic headphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Lung Strategy in Critically Ill Morbid Obese Patients
Status: UNKNOWN
Conditions: Obesity|Respiratory Insufficiency|Right-Sided Heart Failure|Pulmonary Atelectasis|Respiratory Mechanics
Interventions: PROCEDURE: PEEP INCREMENTAL|PROCEDURE: PEEP DECREMENTAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of AZD0284 and IV Microtracer Study
Status: COMPLETED
Conditions: Plaque Psoriasis Vulgaris
Interventions: DRUG: AZD0284|DRUG: [14C]AZD0284
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cumulative Live Birth Rate With eSET After Preimplantation Genetic Screening Versus Conventional In-vitro Fertilization
Status: UNKNOWN
Conditions: Infertility
Interventions: PROCEDURE: blastocyst morphologic score|PROCEDURE: blastocyst biopsy and sequencing|PROCEDURE: freeze-all and single thawed blastocyst transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Initially Node Positive Breast Cancer Patients, Could it Omit Axillary Dissection ?
Status: NOT_YET_RECRUITING
Conditions: Sentinel Lymph Node
Interventions: PROCEDURE: sentinle lymphnode biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of the NEXThaler® Device (DPI - Dry Powder Inhaler) on the Central and Peripheral Airway Dimensions in Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclomethasone dipropionate 100 µg + formoterol fumarate 6 µg|RADIATION: CT thorax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ocean Rowing Muscle Metabolism. 1. What Effect Does Rowing 3000 Miles Across Atlantic Ocean Have on Calf Muscle Size? 2. In the Catabolic State of Extreme Endurance, is Muscle Loss Uniform or Can the Human Body Select Depending on Load and Nutrient Availability?
Status: COMPLETED
Conditions: Exercise
Interventions: OTHER: Ocean row
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Dexmedetomidine and Delirium After Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgical Procedures
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Warm Skin Disinfection Reduce the Pain Peripheral Central Catheter Application in Premature Babies?
Status: UNKNOWN
Conditions: Pain, Acute|Premature
Interventions: OTHER: warm group/cold group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Surgical Morbidity and Bone Healing of Impacted Lower Third Molars: Piezosurgery vs. Conventional Instruments
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DEVICE: Piezosurgery|DEVICE: Conventional burs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: calcitriol|DRUG: mitoxantrone hydrochloride|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Ehlers-Danlos Syndrome|Anesthesia, Local
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: Lidocaine Injection 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparative Study of the Effect of Two Partographs on the Cesarean Section Rate in Women in Spontaneous Labour
Status: TERMINATED
Conditions: Dystocia
Interventions: OTHER: New partograph based on the studies of Neal and Lowe|OTHER: Classical partograph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study of SOL (S-1,Oral Leucovorin,and Oxaliplatin) for Colorectal Cancer in China
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: S-1, leucovorin, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomechanical and Neurophysiological Evaluation of the Effect of a Motor Block and an Injection of Botulinum Toxin on the Stiffness of the Paretic Sural Triceps Muscle
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: OTHER: Selective nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: H101 Combined With TACE for Primary Hepatocellular Carcinoma With Portal Vein Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Primary Hepatocellular Carcinoma|Portal Vein Thrombosis
Interventions: DRUG: Recombinant human adenovirus type 5 + TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pegylated Interferon Alfa in Polycythemia Vera
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: pegylated interferon-alfa 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Two Different Dose Adjustment Regimens for Insulin Degludec/Insulin Aspart in Subjects With Type 2 Diabetes Mellitus Previously Treated With Insulin Glargine
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics
Status: COMPLETED
Conditions: Geriatrics|Outpatients|Personal Satisfaction
Interventions: DRUG: Dexmedetomidine infusion|DRUG: Remifentanil infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Spices 1|DIETARY_SUPPLEMENT: Spices 2|DIETARY_SUPPLEMENT: Spices 3|DIETARY_SUPPLEMENT: Herbs 1|DIETARY_SUPPLEMENT: Herbs 2|DIETARY_SUPPLEMENT: Control drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Tranexamic Acid for Reducing Blood Requirement in Patients Undergoing Major Gastro-intestinal Surgery
Status: UNKNOWN
Conditions: Gastric Cancer|Pancreatic Cancer|Hepatocellular Cancer|Colon Cancer
Interventions: DRUG: Tranexamic acid|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome|Chronic Fatigue Syndrome|Myalgic Encephalomyelitis|Exercise Intolerance|Dysautonomia|Low Ventricular Filling Pressures (Preload Failure)|Postural Orthostatic Tachycardia Syndrome|Orthostatic Hypotension|Fibromyalgia
Interventions: DRUG: Pyridostigmine Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Doses of Letrozole in Ectopic Pregnancy
Status: COMPLETED
Conditions: Ectopic Pregnancy
Interventions: DRUG: Letrozole tablets|PROCEDURE: laparoscopic salpingectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of VSL#3 in Irritable Bowel Syndrome in Children
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Placebo|DRUG: VSL#3 900 billion bacteria|DRUG: VSL#3 90 billion bacteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Locally Advanced Breast Cancer|Recurrent Breast Cancer|Metastatic Breast Cancer|ER+ Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors
Status: COMPLETED
Conditions: Neuroblastoma|Rhabdomyosarcoma|Osteosarcoma|Ewing Sarcoma|Wilms Tumor|Desmoplastic Small Round Cell Tumor
Interventions: DRUG: Enoblituzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-ICE and High-Dose Cyclophosphamide With PET/CT for Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: High-dose cyclophosphamide|PROCEDURE: PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dating Matters: Strategies to Promote Healthy Teen Relationships
Status: COMPLETED
Conditions: Teen Dating Violence|Healthy Dating Relationship Behaviors
Interventions: BEHAVIORAL: Dating Matters Comprehensive Approach|BEHAVIORAL: Standard of Care Safe Dates Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Mycophenolate Mofetil 500 mg Tablets of Dr.Reddy's Laboratories Limited Under Fasting Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement Adherence to Clinical Practice Guidelines Using the Clinical Decision Support System in Patients With Hypertension and Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Arterial Hypertension
Interventions: OTHER: CDSS ("MedicBK")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Computer Generated After Visit Summaries
Status: COMPLETED
Conditions: Primary Care Patients With Chronic Conditions
Interventions: OTHER: Maximum After Visit Summary Content|OTHER: Intermediate After Visit Summary Content|OTHER: Minimum After Visit Summary Content|OTHER: Usual AVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Famitinib in Patients With Advanced Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Renal Cell Cancer|Metastatic Renal Cell Cancer
Interventions: DRUG: Famitinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relapse Prevention Program for Reducing Relapse and Fear of Food in People With Anorexia Nervosa
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Food Exposure Therapy and Ritual Prevention with Motivational Enhancement for Relapse Prevention in Anorexia Nervosa (AN-EX/RP)|BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Ibuprofen 800 mg oral|DRUG: Ketorolac 30mg oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery
Status: UNKNOWN
Conditions: Opioid Free Anesthesia
Interventions: PROCEDURE: pre emptive local anaesthetic wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate the Effects of AZD1981 on the QT Interval
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD1981, 2000mg|DRUG: AZD1981, 200mg|DRUG: Moxifloxacin, 400mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dural Tenting Sutures in Neurosurgery - is it Necessary?
Status: COMPLETED
Conditions: Epidural Hematoma
Interventions: PROCEDURE: No dural tenting techniques|PROCEDURE: Dural tenting techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stimulation of Auricular Acupuncture-Point for Chemotherapy-Induced Nausea/Vomiting
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: Auricular acupuncture|PROCEDURE: Sham auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
Status: COMPLETED
Conditions: Early Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Methotrexate|DRUG: Mycophenolate mofetil|DRUG: Cyclophosphamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rivastigmine Bioequivalence Trial With Multiple Application of Transdermal Patches (13.3mg/24h)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RID-TDS 13.3 mg/24 h|DRUG: Exelon® 13.3 mg/24 h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of 12-Week High-intensity Interval Training With Mindfulness-based Recovery on Executive Function, Fitness, and Mindfulness in Children
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: MF-HIIT|BEHAVIORAL: HIIT-only|BEHAVIORAL: MF-only|BEHAVIORAL: Sedentary activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Cryotherapy in Shoulder Arthroplasty Patients
Status: WITHDRAWN
Conditions: Pain, Shoulder
Interventions: DEVICE: Aircast Cryo Cuff (Shoulder) and Aircast Cryo Cuff I/C Motorized Cooler|DEVICE: Icepacks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disruptive bEhavior manageMEnt ANd Prevention in Hospitalized Patients Using a behaviORal Intervention Team
Status: COMPLETED
Conditions: Behavioral Problem
Interventions: BEHAVIORAL: Behavioral Intervention Team|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of FLUTIFORM ® vs Seretide® in Moderate to Severe Persistent Asthma in Subjects Aged ≥12 Years
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Fluticasone/ Formoterol|DRUG: fluticasone/ salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects With Any Progressive Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: ABL503
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|ARDS
Interventions: BIOLOGICAL: ExoFlo|OTHER: Intravenous normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Physical Training and GLP-1 Receptor Agonist Liraglutide Treatment in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Training and liraglutide|OTHER: Training and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Complications - A Probiotic Interventional Study
Status: COMPLETED
Conditions: Preeclampsia|Preterm Birth
Interventions: DRUG: probiotic|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Durvalumab|RADIATION: Stereotactic Ablative Body Radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preference of Rheumatoid Arthritis (RA) Patients of Enbrel® (Etanercept) Auto-Injector Versus Enbrel® Pre-Filled Syringes
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if a Reduction in Pain Can be Measured in Spinal Cord Injured Patients Using a New Study Design
Status: TERMINATED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Pregabalin|DRUG: Placebo for pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Colchicine Plus Phenolic Monoterpenes to Treat COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Standard Treatment|DRUG: Oral administration of Colchicine plus Herbal Phenolic Monoterpene Fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protocol for Evaluation of eLearning of Quality Improvement Methods
Status: COMPLETED
Conditions: Learning|Quality Improvement|eLearning
Interventions: OTHER: QI4U learning|OTHER: Facilitated learning|OTHER: QI4U and Facilitated learning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Asthma Diagnosis Verified by Lung Function
Status: UNKNOWN
Conditions: Asthma|Dyspnea; Asthmatic|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: AsthmaTuner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC