pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: Non-Small-Cell-Lung Cancer (NSCLC)
Interventions: DRUG: 18F-FMISO|OTHER: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Astaxanthin formulation|OTHER: Placebo|OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Umeclidinium (UMEC) as Combination Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UMEC DPI|DRUG: Placebo DPI|DRUG: ICS/LABA medication|DRUG: Albuterol/salbutamol Metered Dose Inhaler (MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glucagon-like Peptide 2 on Gallbladder Motility After a Meal in Young, Healthy Male Subjects
Status: UNKNOWN
Conditions: Effect of Glucagon-like Peptide 2 on Gallbladder Motility
Interventions: DRUG: GLP-2 (1pmol/kg/min)|DRUG: GLP-2 (10pmol/kg/min)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telemedicine on Metabolic Control in Type 1 Diabetes Mellitus Andalusian Patients (PLATEDIAN)
Status: COMPLETED
Conditions: Telemedicine
Interventions: OTHER: Telemedicine group|OTHER: Conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2510924 and Durvalumab in Participants With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: LY2510924|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Dysmenorrhea and Osteopathic Treatment
Status: UNKNOWN
Conditions: Pelvic Pain|Pelvic Pain Syndrome|Sexual Dysfunction
Interventions: OTHER: Control Group|OTHER: Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Lyoplant® Onlay in Repairing Cerebral Dura Mater
Status: UNKNOWN
Conditions: Replacement and Extension of Connective Tissue Structure in Neurosurgery
Interventions: DEVICE: Lyoplant® Onlay/DURAFORM™ Dural Graft Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Patient Awareness About Possibility Of Occurrence Of Pain During Propofol Injection On The Rate Of Incidence And Severity Of Pain During Injection .
Status: COMPLETED
Conditions: Effect of Patient Awareness on Incidence and Severity of Propofol Injection Induced Pain
Interventions: BEHAVIORAL: Awareness about propofol injection induced pain
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above
Status: COMPLETED
Conditions: Pneumococcal Infections|Streptococcal Infections|Bacterial Infections
Interventions: BIOLOGICAL: 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine（CRM197,TT）|BIOLOGICAL: 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: VPM1002|BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EUS vs EGD in Emergency Room Patients Referred for EGD
Status: WITHDRAWN
Conditions: Abdominal Pain
Interventions: DIAGNOSTIC_TEST: Esophago-gastro-duodenoscopy (EGD)|DIAGNOSTIC_TEST: Endoscopic ultrasound (EUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Inflammatory Myopathies|Diffuse Cutaneous Systemic Sclerosis|SLE Nephritis|ANCA Associated Vasculitis
Interventions: DRUG: KYV-101|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Grayson Acrylic Formed Nasoalveolar Molding Appliances.
Status: UNKNOWN
Conditions: Cleft Lip and Palate|Bilateral Cleft Lip/Palate
Interventions: DEVICE: Presurgical vacuum formed nasoalveolar molding aligners|DEVICE: Conventional Grayson acrylic formed nasoalveolar molding appliances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation in a Population Suffering From Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain
Interventions: DEVICE: PBM|OTHER: PLACEBO PBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation
Status: RECRUITING
Conditions: Extensive Stage Lung Small Cell Carcinoma|Stage IV Lung Cancer
Interventions: DRUG: Carboplatin|BIOLOGICAL: Atezolizumab|DRUG: Etoposide|RADIATION: Total Body Irradiation|RADIATION: Hypofractionated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-month Randomised, Double-blind, Open Arm Comparator, Phase IIb, With AZD9056, in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD9056|DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cartilage Defects With Peripheral Blood Stem Cells
Status: UNKNOWN
Conditions: Cartilage Injury
Interventions: GENETIC: autologous peripheral blood mesenchymal stem cell|PROCEDURE: Microfracture|COMBINATION_PRODUCT: Microfracture + collagen membrane|PROCEDURE: Autologous osteochondral transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study of JS004 in Subjects With Recurrent/Refractory Malignant Lymphoma of China
Status: COMPLETED
Conditions: Recurrent/Refractory Malignant Lymphoma
Interventions: BIOLOGICAL: JS004 , Recombinant humanized IgG4k monoclonal antibody specific to BTLA for injection Intravenous infusion|BIOLOGICAL: Drug：JS001, Intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Standard Lucentis Therapy With Micropulse Diode Laser for the Treatment of Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: ranibizumab|PROCEDURE: micropulse diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identify the Usefulness of In-person and Virtual Quit Smoking Programs
Status: COMPLETED
Conditions: Cigarette Smoking|Tobacco Use
Interventions: BEHAVIORAL: Enhanced in-person peer-motivation smoking cessation|BEHAVIORAL: Virtual peer-motivation smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mental Health Pathways in Internet Support Groups
Status: COMPLETED
Conditions: Depression|Stress|Anxiety
Interventions: BEHAVIORAL: Order by time and topic|BEHAVIORAL: Order by information relevance|BEHAVIORAL: Order by social relationship|BEHAVIORAL: Order by help giving|BEHAVIORAL: Order by self-disclosure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IOBA - Impact on Body Awareness
Status: COMPLETED
Conditions: Perception, Self|Body Image|Self-Assessment
Interventions: PROCEDURE: Massage|PROCEDURE: Gymnastics|OTHER: Lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Evaluate Pharmacokinetics and Safety of Two Different Formulation of Rebamipide in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Rebamipide SR 150mg|DRUG: Rebamipide IR 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Portal Vein Embolization Using Coils Plus TAGM vs Multiple Coils for Patients With Perihilar Cholangiocarcinoma or Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Portal Vein Occlusion|Cholangiocarcinoma, Perihilar|Hepatocellular Carcinoma|Liver; Hypertrophy, Acute
Interventions: PROCEDURE: PVE with coils plus TAGM|PROCEDURE: PVE with multiple coils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Neurologic Manifestations|Uremic Encephalopathy
Interventions: DIAGNOSTIC_TEST: S100β, Neuron specific enolase (NSE) and Glial fibrillary acidic protein (GFAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beneficial Bacteria to Prevent Malnutrition and Diarrhea in Pakistani Infants
Status: COMPLETED
Conditions: Malnutrition|Diarrhea
Interventions: DRUG: LGG yogurt|OTHER: Placebo yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome|Bladder Pain Syndrome|Low Dose Naltrexone|Low-dose Naltrexone|Naltrexone
Interventions: DRUG: low-dose naltrexone|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacokinetics of CT1812 in Older Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: CT1812
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogeneic Mesenchymal Stromal Cells for Angiogenesis and Neovascularization in No-option Ischemic Limbs
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Cardiovascular Diseases|Vascular Diseases
Interventions: DRUG: Allogeneic Mesenchymal Stromal Cell|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Impact of Neopterin on Resumption of Walking After a Fracture of the Upper Neck of the Femur in the Elderly
Status: RECRUITING
Conditions: Fracture of Neck of Femur|Resumption of Walking
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Loop Drainage Versus Incision and Drainage for Abscesses in Children
Status: COMPLETED
Conditions: Abscess of Skin and/or Subcutaneous Tissue
Interventions: PROCEDURE: Vessel Loop Drainage|PROCEDURE: Incision and Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mechanical Ventilation Strategy on Lung Injury in Patients With Less Severe Acute Respiratory Distress Syndrome: Targeted on RAGE
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: check biomarker :RAGE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function
Status: ENROLLING_BY_INVITATION
Conditions: Renal Impairment
Interventions: DRUG: 100 mg Resmetirom Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem Glioma
Status: TERMINATED
Conditions: Diffuse Intrinsic Pontine Glioma
Interventions: BIOLOGICAL: Tumor Lysate Vaccine|DRUG: Imiquimod|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Status: RECRUITING
Conditions: Aortic Stenosis, Calcific|Aortic Valve Stenosis
Interventions: DEVICE: SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depression Treatment and Screening in Ovarian Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: OTHER: Telephone Counseling|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Atherectomy on VasculaR Functions
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Claudication, Intermittent
Interventions: OTHER: Atherectomy|OTHER: POBA and DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of The Acute Effects of Different Stretching Methods on Ankle Joint Range In Healty Older Adults
Status: COMPLETED
Conditions: Older Adults|Range of Motion|Ankle Injuries
Interventions: OTHER: Static Stretching Method Group|OTHER: PNF Stretching Method Group|OTHER: Myofascial Relaxation Method Group- Roller Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Preparation for Colorectal Surgery: Impact of Video Education
Status: COMPLETED
Conditions: Use of Video Education|Colorectal Surgery
Interventions: PROCEDURE: The study group will get a video and leaflet on enhanced recovery|PROCEDURE: The control group will receive a leaflet only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trail of Acupuncture and Herbs for Post-stroke Cogntive Impairment
Status: UNKNOWN
Conditions: Post-stroke Cognitive Impairment
Interventions: COMBINATION_PRODUCT: Chinese traditional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the 'eNutri' Online Personalised Nutrition App in the United Kingdom (UK)
Status: UNKNOWN
Conditions: Dietary Modification|Dietary Habits
Interventions: BEHAVIORAL: Non-personalised diet advice delivered via the eNutri app (control)|BEHAVIORAL: Personalised diet advice delivered via the eNutri app (intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Precision Sensorimotor Neurorehabilitation Through Personalized Stimulation Loops
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Hyper-personalized feedback (HPF intervention)|BEHAVIORAL: Targeted auditory stimulation during sleep (TASS verum intervention)|BEHAVIORAL: Control targeted auditory stimulation during sleep (TASS sham intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Different Components of Online Acceptance and Commitment Therapy for People With Chiari Malformation
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Chiari Malformation
Interventions: BEHAVIORAL: Online Acceptance and Commitment Therapy Intervention + Phone Coaching|BEHAVIORAL: Online Acceptance and Commitment Therapy Intervention without phone coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Excretion of [¹⁴C]Etelcalcetide (AMG 416) in Patients With End Stage Renal Disease (ESRD) Receiving Dialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism in Patients With ESRD on Hemodialysis
Interventions: DRUG: [¹⁴C]Etelcalcetide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer
Status: RECRUITING
Conditions: Esophagus Adenocarcinoma|Esophagus Squamous Cell Carcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia|Bone Marrow Failure Syndromes
Interventions: PROCEDURE: Bone marrow transplant|DRUG: Thymoglobulin|DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: TBI|DRUG: Mesna|DRUG: Tacrolimus|DRUG: Mycophenolic acid mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Blocks for Lateral Condyle Fractures
Status: RECRUITING
Conditions: Fractures, Closed|Humeral Fractures|Pain
Interventions: DRUG: Ropivacaine|OTHER: Puncture Wound and Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMDR vs Supportive Therapy in Relapse Prevention in Traumatized Bipolar Patients
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: EMDR therapy|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Goserelin/Letrozole in Premenopausal Patients vs Letrozole Alone in Postmenopausal Patients With MBC
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Letrozole ,Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cemented K-wire Fixation vs Open Transfixion Pinning
Status: COMPLETED
Conditions: Closed Fracture of Finger|Finger Fracture
Interventions: DEVICE: Cemented K-wire|DEVICE: Transfixion Pinning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate IMG-007 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: IMG-007 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of a Comprehensive Behavioral Intervention in Patient Post TKA
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: BEHAVIORAL: Comprehensive Behavioral Intervention|OTHER: Standard of Care Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validity of AI in Treatment of the Musculoskeletal Conditions by Vifive
Status: RECRUITING
Conditions: Shoulder Adhesive Capsulitis|Knee Osteoarthritis
Interventions: DEVICE: ViFIVE Digital Care Progrma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Make Better Choices Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Increase healthy activity and increase healthy eating|BEHAVIORAL: Decrease unhealthy activity and increase healthy eating|BEHAVIORAL: Increase physical activity and decrease unhealthy eating|BEHAVIORAL: Decrease sedentary activity and decrease unhealthy eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Thromboembolic Events in Patients Undergoing Thromboprophylactic Treatment With ENOXA® vs Lovenox®
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Thromboembolic Event
Interventions: DRUG: Enoxaparin 4000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of CDOP vs CHOP for Newly Diagnosed Peripheral T-cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: pegylated liposomal doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alginate Dressings Versus Gauge Dressings After Pilonidal Cyst Resection: Examination of the Quality of Life
Status: TERMINATED
Conditions: Pilonidal Cyst/Fistula
Interventions: OTHER: Alginate dressings|OTHER: Simple gauze dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord-derived Mesenchymal Stem Cell Infusion in the Management of Adult Liver Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: Human umbilical cord-derived mesenchymal stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Phosphate Lowering Using Sucroferric Oxyhydroxide (PA21) on Calcification Propensity of Serum
Status: COMPLETED
Conditions: Endstage Renal Disease
Interventions: DRUG: low-dose sucroferric oxyhydroxide|DRUG: high-dose sucroferric oxyhydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Amphetamine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: NRP104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Bioequivalence of "Crecheck Tablet 2.5 mg (Rosuvastatin Calcium)" and "Crestor Tablet 5 mg (Rosuvastatin Calcium)" in Healthy Adult Subjects
Status: COMPLETED
Conditions: Primary Hypercholesterolemia|Combined Hyperlipidemia
Interventions: DRUG: Crecheck Tablet 2.5 mg|DRUG: Crestor Tablet 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials of Two Non-drug Treatments for Chronic Depression
Status: COMPLETED
Conditions: Mood Disorders|Depressive Disorders|Depression|Chronic Depression
Interventions: DEVICE: Bright light box|DEVICE: High-output negative ion generator|DEVICE: Low-output negative ion generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic(PK)/Pharmacodynamics(PD) Study of SHR7280 Tablets in Premenopausal Subjects With Endometriosis.
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: SHR7280|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Supplementation With Creatine on Systemic Microvascular Endothelial Function in Vegetarian Individuals
Status: COMPLETED
Conditions: Endothelial Dysfunction|Hyperhomocysteinemia
Interventions: DIETARY_SUPPLEMENT: monohydrate and micronized creatine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partial Breast Irradiation Using Interstitial Permanent Palladium-103 Seed Implant
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Stage Breast Cancer
Interventions: RADIATION: Stranded palladium seed interstitial implant|DEVICE: 3 dimensional breast ultrasound|DEVICE: Computerized tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose-Escalation Study to Evaluate Tolerability, Safety & PK of INO-8875 in Healthy Older-Adult Volunteers
Status: COMPLETED
Conditions: Health
Interventions: DRUG: INO-8875|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Orally Disintegrating Selegiline in Parkinson's Patients Experiencing Adverse Effects With Dopamine Agonists
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: orally disintegrating selegiline (Zelapar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dorzolamide-timolol in Combination With Anti-vascular Endothelial Growth Factor Injections for Wet Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration|Wet Macular Degeneration
Interventions: DRUG: Dorzolamide-timolol|OTHER: Artificial tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Whey Protein on Blood Pressure
Status: COMPLETED
Conditions: High Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Soy Protein|DIETARY_SUPPLEMENT: Control (carbohydrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acthar in Treatment of Refractory Dermatomyositis and Polymyositis
Status: COMPLETED
Conditions: Dermatomyositis|Polymyositis
Interventions: DRUG: Adrenocorticotropic Hormone Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meditative Slow Breathing or Isha Kriya Meditation in Improving Cancer-Related Symptoms in Hospitalized Participants With Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: OTHER: Best Practice|PROCEDURE: Meditation Therapy|PROCEDURE: Meditation Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Prostate Cancer
Interventions: OTHER: GA+M Intervention|OTHER: RSM intervention|OTHER: GA+RSM intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel Brain Neurotechnology for Optimizing Precision Mirror Therapy in Stroke
Status: RECRUITING
Conditions: Cerebrovascular Accident
Interventions: DEVICE: Transcranial random noise stimulation (tRNS)|DEVICE: sham tRNS|BEHAVIORAL: the unilateral MT|BEHAVIORAL: the bilateral MT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexmedetomidine and Remifentanil on Carotid Patients
Status: TERMINATED
Conditions: Carotid Artery Stenosis
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Manipulating Tobacco Constituents in Male Menthol Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: Reduced Nicotine Non-Menthol (RNC)|OTHER: Reduced Nicotine Menthol (RNC-Men)|OTHER: Conventional Nicotine Non-Menthol (CN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A First in Human Study to Assess the Safety, Tolerability of LB54640 in in Healthy Overweight and Obese Subjects
Status: COMPLETED
Conditions: Obese|Overweight|Healthy
Interventions: DRUG: LB64640|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Remotely Administered Functional Capacity Test on Return-to-work Outcomes
Status: COMPLETED
Conditions: Low Back Disorder|Shoulder Disease|Musculoskeletal Injury
Interventions: DIAGNOSTIC_TEST: Remote functional testing protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
Status: RECRUITING
Conditions: Mental Health Wellness 1|Preterm Birth
Interventions: BEHAVIORAL: The Mastery Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Addressing Stress Among Women Entrepreneurs in Ethiopia - Scale up
Status: RECRUITING
Conditions: Mental Stress|Stress|Stress, Job|Emotion Regulation|Violence, Gender-Based|Economic Problems
Interventions: BEHAVIORAL: Stress managment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment With hOKT3gamma1(Ala-Ala) in T1DM
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: hOKT3gamma1(Ala-Ala)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Use of PAIN-Advanced Dementia Scale in Emergency Departments
Status: NOT_YET_RECRUITING
Conditions: Dementia|Hip Pain|Emergency Department Patient|Pain in Advanced Dementia Scale
Interventions: OTHER: PAINAD EHR Prompt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Saphenous Nerve and Nerve to Vastus Medialis Block Within Subsartorial Femoral Triangle on Quadriceps Strength
Status: COMPLETED
Conditions: Saphenous Nerve Block|Regional Anesthesia Morbidity|Postoperative Pain
Interventions: PROCEDURE: SSFTB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding Delivery of an Evidence-based Weight-loss Intervention to Enhance Access and Reach Underserved Groups After TBI
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Telehealth-delivered Group Lifestyle Balance for people with TBI (tGLB-TBI)|BEHAVIORAL: Brain Health Group (BHG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Response to High Intensity Interval Resistance Training (HIIRT)
Status: COMPLETED
Conditions: Exercise|Resistance Training
Interventions: OTHER: High Intensity Interval Resistance Training|OTHER: Traditional Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of Rilonacept in Muckle-Wells Syndrome (MWS) or Schnitzler Syndrome (SchS)
Status: COMPLETED
Conditions: Muckle-Wells Syndrome|Schnitzler Syndrome
Interventions: DRUG: rilonacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RT-CGMS in Patients With Type 1 Diabetes Mellitus Treated With an Implantable Pump
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Real-Time Continuous Glucose monitoring System (RT-CGMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: RADIATION: Hypofractionated Stereotactic Irradiation (HFSRT)|DRUG: Pembrolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Trial of Autologous Humanized Anti-cluster of Differentiation Antigen 19/20(CD19/CD20) Dual Specific CAR-T Cells Injection
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: Autologous humanized anti-CD19 and anti-CD20 dual specific CAR-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With DC Vaccines for Recurrent Brain Tumors
Status: COMPLETED
Conditions: Malignant Glioma|Astrocytoma|Glioblastoma
Interventions: DRUG: nivolumab|BIOLOGICAL: DC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin Combined With Simvastatin for Treatment of Intrabony Defect in Chronic Periodontitis
Status: COMPLETED
Conditions: Three Wall Intrabony Defects in Chronic Periodontitis
Interventions: DRUG: Platelet rich fibrin and simvastatin|BIOLOGICAL: Platelet rich fibrin|PROCEDURE: Open Flap Debridement alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Binimetinib only treatment|DRUG: Encorafenib only Treatment|DRUG: Encorafenib & Binimetinib Treatment|DRUG: Treatment of Encorafenib & Binimetinib & Ribociclib|DRUG: Treatment of Encorafenib & Binimetinib & Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients
Status: COMPLETED
Conditions: Cancer|Head and Neck Cancer|Pelvic Cancer|Nervous System Neoplasms|Thoracic Neoplasms
Interventions: DRUG: Sunitinib|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Atezolizumab in Combination With Other Immune-Modulating Therapies in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Interferon alfa-2b|DRUG: Ipilimumab|DRUG: Obinutuzumab|DRUG: PEG-interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Inflammation in Psoriasis-Ustekinumab (VIP-U)
Status: COMPLETED
Conditions: Psoriasis|Cardiovascular Disease
Interventions: DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph+ B-ALL
Status: RECRUITING
Conditions: B-Cell Acute Lymphoblastic Leukemia, Adult
Interventions: DRUG: CAR-T cells targeting CD19 and CD22
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glyburide/Metformin 5 mg/500 mg Tablets|DRUG: Glucovance® 5 mg/500 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Disability and Quality of Life of Patients Suffering From Multiple Sclerosis and Treatment With Immunosuppressant
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Biocompatibility and Performances of 4 Dialyzers in Different Mode Treatments
Status: COMPLETED
Conditions: End Stage Renal Disease|Inflammation
Interventions: DEVICE: VIE A Hemodialyzer|DEVICE: Rexsys 27H hemodialyzer|DEVICE: Leoceed 21HX hemodialyzer|DEVICE: Polypure 22S+ hemodialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Ionic Contra-Viral Therapy in Actinic Keratosis
Status: UNKNOWN
Conditions: Actinic Keratosis
Interventions: DRUG: ICVT Topical Gel|DRUG: Furosemide Topical Gel|DRUG: Digoxin Topical Gel|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pharmacokinetics|Pharmacogenomics|Oxycodone
Interventions: DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Continuing Cancer Service Model Emphasizing on Functional Restoration: Model for Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Quality of Life
Interventions: OTHER: SG will be screened every time when they visit the clinics.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Phonological Awareness Skills And Home Environment Literacy in Cochlear Implant Users
Status: COMPLETED
Conditions: Cochlear Implants|Child Language|Literacy|Phonological (Speech) Disorder
Interventions: OTHER: The Turkish Early Language Development Test (TEDIL)|OTHER: The Family Literacy Scale|OTHER: The Early Childhood Phonological Sensitivity Scale (PASECP)|OTHER: The Early Literacy Home Environment Scale (ELHES)|OTHER: Demographic Questionaries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Attune Cementless
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Associated With Hospitalization for Dengue and Dengue Severity: Hospital-based Cohort Study on Reunion Island
Status: ACTIVE_NOT_RECRUITING
Conditions: Dengue Fever With Warning Signs
Interventions: OTHER: blood sampling|OTHER: questionnary of health estate during 18 month
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multi-center Randomized Controlled Trial of Intraportal Chemotherapy Combined With Adjuvant Chemotherapy (mFOLFOX6) for Stage II and III Colon Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Metastasis
Interventions: DRUG: FUDR +oxaliplatin|DRUG: oxaliplatin+Leucovorin+5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Test and Reference 50 mg Eplerenone Film-coated Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Healthy Subjects
Interventions: DRUG: Efez 50 mg eplerenone film-coated tablets|DRUG: INSPRA® 50 mg eplerenone film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Accuracy, Feasibility and Acceptance of Continuous Glucose Monitoring in Critically Ill Patients
Status: COMPLETED
Conditions: Glucose Metabolism Disorders|Diabetic Blood Glucose Monitoring|Critical Illness
Interventions: DEVICE: Continuous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of Sublingual Immunotherapy to Treat Ragweed Allergies
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Standardized Ragweed Allergenic Extract|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerance, Pharmacokinetics, and Preliminary Antineoplastic Activity of AK132 in Advanced Malignant Solid Tumor
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Tumor
Interventions: DRUG: AK132
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Malignant Neoplasm|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: BEHAVIORAL: Receive lifestyle modification alone|BEHAVIORAL: Metformin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION