pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: First Human Dose Trial Investigating Safety, Tolerability and Pharmacokinetics of NNC0194-0499 in Male Subjects With Overweight or Obesity
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC0194-0499|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Pulmonary and Venous Thromboembolism in IVF Pregnancies After Fresh and Frozen Embryo Transfer
Status: COMPLETED
Conditions: Assisted Reproductive Techniques|Pregnancy|Pulmonary Embolism|Venous Thromboembolism|Fresh Embryo Transfer|Frozen Embryo Transfer
Interventions: PROCEDURE: Fresh or frozen embryo transfer IVF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Administration During Chemotherapy to Reduce Ovarian Failure Following Chemotherapy in Early Stage, Hormone-Receptor Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Standard cyclophosphamide|DRUG: Goserelin (Zoladex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Oral Bisphosphonate (MK-0822-076)
Status: TERMINATED
Conditions: Osteoporosis
Interventions: DRUG: odanacatib|OTHER: placebo to odanacatib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital CBT for Insomnia and Depression
Status: RECRUITING
Conditions: Depression|Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Cognitive Behavioral Therapy for Depression|BEHAVIORAL: Mood Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of Multiple Intravenous Doses of ANZ-521 in Adults With Chronic Hepatitis C Virus
Status: TERMINATED
Conditions: Chronic Hepatitis C
Interventions: DRUG: ANZ-521|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Bioavailability of CBD and THC in an Emulsion Product in a Healthy Population
Status: COMPLETED
Conditions: Healthy|Cannabis
Interventions: DRUG: Cannabis Preparation|DRUG: Cannabis Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bosentan for Mild Pulmonary Vascular Disease in Asd Patients.
Status: COMPLETED
Conditions: Heart Septal Defects, Atrial
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genital Self İmage and Satisfaction With Genital Appearance
Status: NOT_YET_RECRUITING
Conditions: Women
Interventions: OTHER: The intervention group, which was randomly selected by randomisation and accepted to participate in the study, is planned to receive 3-week training sessions between 30-45 minutes.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Individualized Comprehensive Home-Centred Activity Based Therapy for Children With Diplegic Cerebral Palsy
Status: COMPLETED
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: Individualized comprehensive home centred activity based programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Advanced Glycation Endproducts on Satiety and Inflammation
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes|Insulin Resistance|Cardiovascular Disease
Interventions: OTHER: Dietary meal intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Small Cell Carcinoma|Neuroendocrine Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Dostarlimab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP)
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: DRUG: Rectal indomethacin 100mg one time before or after ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease|Single-ventricle|Thrombosis
Interventions: OTHER: Collecting discarded blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Childhood Alopecia Areata Study Using the 308-nm Excimer Laser
Status: WITHDRAWN
Conditions: Alopecia Areata
Interventions: DEVICE: 308-nm excimer laser to alopecia patch|DEVICE: Liquid light guide tip on laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Accuracy of Referrals of Patients With Chest Pain
Status: UNKNOWN
Conditions: Chest Pain|Acute Coronary Syndrome|Myocardial Infarction|Myocardial Ischemia|Heart Attack
Interventions: DIAGNOSTIC_TEST: modified HEART score (including POC hs cTnI analysis)|OTHER: Standard care and triage according to the local (EMT)protocol.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rice Bran Supplementation in Treated HIV Infection
Status: COMPLETED
Conditions: Inflammation in HIV Infection
Interventions: DIETARY_SUPPLEMENT: arabinoxylan rice bran|DIETARY_SUPPLEMENT: Placebo for arabinoxylan rice bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HB0030 Injection in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection|DRUG: HB0030 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unfavorable MRI But Favorable 68Ga-PSMA PET/MRI for Primary Prostate Cancer Detection
Status: UNKNOWN
Conditions: Prostate Neoplasm
Interventions: DEVICE: multiparametric MRI and 68Ga-PSMA PET/MRI|PROCEDURE: Prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study for the Treatment of Transfusional Iron Overload in Myelodysplastic Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Iron Overload
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery
Status: TERMINATED
Conditions: Stage I Uterine Sarcoma AJCC v7|Uterine Corpus Leiomyosarcoma
Interventions: OTHER: Clinical Observation|DRUG: Docetaxel|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Filgrastim|DRUG: Gemcitabine Hydrochloride|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entecavir Combined Short-term Intravenous Hepatitis B Immune Globulin (HBIG) to Prevent Hepatitis B Recurrence After Liver Transplantation
Status: UNKNOWN
Conditions: Hepatitis B|Liver Transplantation
Interventions: DRUG: Entecavir combined long-term low-dose HBIG group intramuscular|DRUG: Entecavir combined HBIG group short-term high-dose intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training on Vascular Endothelial Function of Patients Submitted to Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Vasodilation
Interventions: OTHER: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nursing Students' Visits to Older Adults With Multiple Chronic Conditions
Status: COMPLETED
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Nursing students' home-visit programme|BEHAVIORAL: Standard care from Public Andalusian Health Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relevance of Imiquimod as Neo-adjuvant Treatment to Reduce Excision Size and the Risk of Intralesional Excision in Lentigo Malignant of the Face
Status: COMPLETED
Conditions: Lentigo Maligna Melanoma (Head or Neck)
Interventions: DRUG: Imiquimod cream + surgery|DRUG: Placebo + surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Beyond Progression in HER2 Positive Metastatic Gastric Cancer
Status: WITHDRAWN
Conditions: Gastric Cancer
Interventions: DRUG: Trastuzumab|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Programmed Cell Death Protein 1 Inhibitor|Radiotherapy
Interventions: DRUG: Toripalimab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|RADIATION: Intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) in Combination With Dacarbazine in Participants With Unresectable/Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Bevacizumab|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Costs, Effectiveness, QALYs, and Efficiency of Bioabsorbable Devices in Daily Clinical Practice
Status: UNKNOWN
Conditions: Coronary Stenosis Treated With Implant of Bioresorbable Devices
Interventions: DEVICE: Coronary angioplasty with implant of bioresorbable device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MCS110 Combined With Neoadjuvant Doxorubicin, Cyclophosphamide, and Weekly Paclitaxel in Patients With Hormone-Receptor Positive and HER2- Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Cancer of Breast
Interventions: BIOLOGICAL: MCS110|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|PROCEDURE: Bone marrow aspirate|PROCEDURE: Peripheral blood samples|PROCEDURE: Tumor tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tramadol in COVID-19 Egyptian Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Tramadol|OTHER: Standard care delivered in the isolation hospitals.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Related Anemia
Status: COMPLETED
Conditions: Anemia|Non-Myeloid Malignancies
Interventions: DRUG: Darbepoetin alfa SC|DRUG: Darbepoetin alfa IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
Status: NOT_YET_RECRUITING
Conditions: Glioma
Interventions: DRUG: Retreatment Rhenium Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Talazoparib|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: BEHAVIORAL: De-implementation Strategy for Bronchiolitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extended Criteria For Fetal Myelomeningocele Repair
Status: COMPLETED
Conditions: Obesity|Myelomeningocele|Pregnancy|Diabetes Mellitus in Pregnancy|Fetal Anomaly
Interventions: PROCEDURE: Open Fetal Repair of Myelomeningocele
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Absorption, Metabolism and Excretion of [14C] HQP1351 in Humans
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: DRUG: [14C] HQP1351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STRATAGEM: Strategy for Managing Antiplatelet Therapy in the Perioperative Period of Non Coronary Surgery
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: aspirin 75 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Bone Flap Fixation Systems For Craniotomy Procedures
Status: COMPLETED
Conditions: Craniotomy
Interventions: DEVICE: Clamp-like system|DEVICE: Plates and screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma|Tumors Metastatic to Brain
Interventions: DRUG: Ipilimumab|RADIATION: Whole-Brain Radiation Therapy (WBRT)|RADIATION: Stereotactic Radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2, Interferon Alfa, and Fluorouracil Compared With Observation in Treating Patients Who Have Undergone Surgery for Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|DRUG: fluorouracil|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Three Influenza Vaccines in Children Aged 4 Years Old to Less Than 18 Years Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: QIVc|BIOLOGICAL: TIV1c|BIOLOGICAL: TIV2c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects.
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Dapagliflozin/metformin XR FDC 5/500 mg|DRUG: Dapagliflozin/metformin XR FDC 10/1000 mg|DRUG: Dapagliflozin 5 mg + Metformin 500 mg XR|DRUG: Dapagliflozin 10 mg + Metformin 1000 mg XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors
Status: UNKNOWN
Conditions: Carcinoma|Melanoma|Bladder Cancer|Colorectal Cancer
Interventions: BIOLOGICAL: Tumor antigen-sensitized DC vaccine and their sensitized T cells subcutaneous administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV) Associated With Highly Emetogenic Chemotherapy (0869-801)(COMPLETED)
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: MK0869, aprepitant / Duration of Treatment: 3 days|DRUG: Comparator: ondansetron / Duration of Treatment: 4 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Metastatic Tumor|Advanced Solid Tumor|Renal Cell Carcinoma|Ovarian Cancer|Cervix Cancer|Head and Neck Squamous Cell Carcinoma|Nasopharyngeal Carcinoma
Interventions: DRUG: CHT101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviewing-Based Health Behavior Training in Chronically Ill Migrant Women
Status: NOT_YET_RECRUITING
Conditions: Motivational Interviewing|Health Care Seeking Behavior|Migrants|Women
Interventions: BEHAVIORAL: Health Seeking Behavior Training Based on Motivational Interviewing Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Omega-3 polyunsaturated fatty acid supplementation|OTHER: Resistance exercise|DIETARY_SUPPLEMENT: Placebo - appearance-matched oil supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Weight-based Flow Rates for Children With Bronchiolitis on High-Flow Nasal Cannula: A Pilot Randomized Control Trial
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: OTHER: Weight-Based Flow for High Flow Nasal Cannula (HFNC) (2L/kg/minute)|OTHER: Standard Flow for HFNC (Maximum 8L/minute)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VICOR Study-High Frequency Chest Wall Oscillations (HFCWO) in Patients With Acute Respiratory Failure and Hypersecretion
Status: RECRUITING
Conditions: Acute Respiratory Failure|Acute-on-chronic Respiratory Failure|Airway Clearance Impairment
Interventions: DEVICE: High Frequency Chest Wall Oscillations via The Vest® Airway Clearance System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alitretinoin vs Azathioprine in Severe Non-hyperkeratotic Hand Eczema
Status: UNKNOWN
Conditions: Hand Eczema
Interventions: DRUG: Alitretinoin|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Camrelizumab Combined With Irinotecan or Albumin Paclitaxel for Second-line Treatment of Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Second Line Treatment of Gastric Cancer
Interventions: DRUG: Camrelizumab|DRUG: Albumin-Bound Paclitaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Dexmedetomidine for Treating Opioid Withdrawal
Status: RECRUITING
Conditions: Opioid Use Disorder|Opioid Withdrawal
Interventions: DRUG: BXCL501 (180 micrograms)|DRUG: BXCL501 (240 micrograms)|OTHER: Placebo|OTHER: Lofexidine (Positive Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: ONO-2745 /CNS 7056
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 337 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignancy|Advanced Solid Tumors|Cancer|Oncology|Oncology Patients|Tumors
Interventions: DRUG: AMG 337
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion of Evidence and Applied Research on Intermittent Catheterization After Radical Hysterectomy
Status: RECRUITING
Conditions: Intermittent Catheterization|Conversion of Evidence
Interventions: BEHAVIORAL: intermittent catheterization protocol based on the best evidence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Status: RECRUITING
Conditions: Heart Failure|Systemic Inflammation
Interventions: DRUG: Ziltivekimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults
Status: RECRUITING
Conditions: Shingles|Herpes Zoster Infection|Human
Interventions: BIOLOGICAL: Candidate 1: PF-07915234: VZV modRNA Powder for Suspension for Injection|BIOLOGICAL: Candidate 1: PF-07915234: VZV modRNA Suspension for Injection|BIOLOGICAL: Candidate 2: PF-07921188: VZV modRNA Suspension for Injection|BIOLOGICAL: Candidate 3: PF-07921186: VZV modRNA Suspension for Injection|BIOLOGICAL: Shingrix|BIOLOGICAL: Selected Vaccine Candidate group (Dose level, Schedule)|BIOLOGICAL: Shingrix - SSB|BIOLOGICAL: Candidate 2: PF-07921188: VZV modRNA Powder for Suspension for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Fistulotomy for Biliary Cannulation
Status: UNKNOWN
Conditions: Cholangiocarcinoma|Choledocholithiasis; Cholangitis|Pancreatic Cancer|Pancreatitis
Interventions: PROCEDURE: Fistulotomy - High experienced.|PROCEDURE: Fistulotomy - Low experienced.|PROCEDURE: Conventional (guidewire) cannulation- High experienced|PROCEDURE: Conventional (guidewire) cannulation - Low experienced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Camrelizumab and Apatinib in Intermediate and Advanced Hepatocelluar Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab|DEVICE: TACE|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline as an Adjunctive in Treatment of Negative Symptoms in Chronic Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo oral tablet|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Control Group|DRUG: TTI-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
Status: COMPLETED
Conditions: Brain Diseases|Brain Neoplasms|Central Nervous System Diseases|Neoplasm Metastasis|Nervous System Neoplasms
Interventions: DRUG: ABT-888|RADIATION: Whole Brain Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid Leukemia or Myelodysplastic Syndrome After Hematopoietic Cell Transplantation, the DR. DREAM Trial
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Decoy-resistant interleukin-18|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK 257049|BIOLOGICAL: Tritanrix™ HepB/Hib|BIOLOGICAL: Rouvax™|BIOLOGICAL: Stamaril™|BIOLOGICAL: Polio Sabin™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treating Anorectal Dysfunction in MS
Status: TERMINATED
Conditions: Constipation|Fecal Incontinence|Multiple Sclerosis
Interventions: DRUG: Bisacodyl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Closure of Gastric ESD Defect
Status: UNKNOWN
Conditions: Gastric Dysplasia|Gastric Cancer in Situ
Interventions: PROCEDURE: Endoscopic closure of ESD defect|OTHER: Gastric ESD without closure of ESD defect
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Stereotactic Radiosurgery Following Surgical Resection of Brain Metastases
Status: COMPLETED
Conditions: Brain Metastasis|Neoplasm
Interventions: RADIATION: Radiosurgery dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Efficacy of Trazodone (Desyrel) on Sleep Quality and Pain Management of TMD Patient
Status: TERMINATED
Conditions: TMD|Sleep Bruxism|TMJ Pain|Chronic Pain|Sleep Disorder
Interventions: DIAGNOSTIC_TEST: polysomnography|DRUG: Trazodone|DRUG: Placebos|DIAGNOSTIC_TEST: polysomnography|DRUG: Trazodone|DRUG: placebos|DIAGNOSTIC_TEST: polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Efficacy and Safety of RESTORE Paclitaxel Eluting Balloon Versus RESOLUTE Zotarolimus Eluting Stent for the Treatment of Small Coronary Vessel Disease
Status: COMPLETED
Conditions: Coronary Stenosis
Interventions: DEVICE: Restore DEB（dimeter>2.00 mm）|DEVICE: Resolute DES|DEVICE: Restore DEB（dimeter:2.00 mm）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potassium Nitrate in Polycarboxylate as a Direct Pulp Capping
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulp Disease, Dental
Interventions: OTHER: potassium nitrate in polycarboxilate cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an Adenoviral HIV Vaccine (VRC-HIVADV014-00-VP) With or Without a Plasmid HIV Vaccine (VRC-HIVDNA016-00-VP) in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVADV014-00-VP|BIOLOGICAL: VRC-HIVDNA016-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ropeginterferon Alfa-2b in Essential Thrombocythaemia Patients
Status: RECRUITING
Conditions: Essential Thrombocythaemia
Interventions: DRUG: Ropeginterferon alfa-2b (BESREMi®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Physical Exercise on Endothelial Function in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: High-intensity exercise|PROCEDURE: Low-intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHV
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: QPX7728|DRUG: Placebo|DRUG: QPX2014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization for Obstructive Uropathy Due to Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm|Lower Urinary Tract Symptoms|Urological Manifestations|Prostatic Diseases
Interventions: PROCEDURE: Prostatic Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)
Status: RECRUITING
Conditions: Narcolepsy
Interventions: DRUG: MK-6552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrhythmias, Cardiac|Atrial Flutter
Interventions: DEVICE: Ambulatory ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sorafenib for Imatinib/Sunitinib-failed GIST
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect of Non-invasive Auricular Acupoint Stimulation for the Performance and the Meridian Activities of Archery Athletes
Status: COMPLETED
Conditions: Stress, Physiological|Sport Injury
Interventions: OTHER: Auricular acupoints stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of Low-dose Glucocorticoids and Tofacitinib in Alleviating Moderate to High Disease Activity Rheumatoid Arthritis for 24 Weeks
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tofacitinib|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Performance and 3D Shoulder Kinematics of Asymptomatic Unilateral/Bilateral Overhead Athletes and Non-athletes
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: BEHAVIORAL: Chronic exposure to unilateral overhead sports activity|BEHAVIORAL: Chronic exposure to bilateral overhead sports activity|BEHAVIORAL: Not exposed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial Evaluating OS With Therasphere® + 2nd-Line FOLFOX in Pancreatic Liver Mets
Status: COMPLETED
Conditions: Liver Cancer|Pancreatic Cancer
Interventions: DRUG: FOLFOX7 (Folinic acid, 5-Fluorouracil, and Oxaliplatin)|DEVICE: TheraSpheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Intravenous Magnesium Sulphate on Anaesthesia and Analgesia in Elective General Surgery Patients
Status: RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Pain, Nociceptive|Analgesia|Magnesium
Interventions: DRUG: magnesium bolus followed by normal saline infusion|DRUG: magnesium bolus followed by magnesium infusion|DRUG: normal saline bolus followed by normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Prontosan Wound Irrigation Solution on Venous Ulcers
Status: COMPLETED
Conditions: Wound Care|Venous Ulcer Care|Wound Cleansing|Chronic Wound Care
Interventions: DEVICE: Prontosan wound irrigation solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insulin Degludec/Insulin Aspart in Insulin-naïve Subjects With Type 2 Diabetes Using Two Dosing Regimens
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Intrapartum Care for Saving Life at Birth in Ethiopia Through PartoMa Approach
Status: RECRUITING
Conditions: Stillbirth|Obstetric Complication|Maternal Death|Perinatal Death|Perinatal Morbidity
Interventions: OTHER: PartoMa intervention(Locally achievable intrapartum care guideline), in house LDHF trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Delefilcon A contact lens|DEVICE: Etafilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT on Adjuvant TACE After Hepatectomy for HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Transarterial chemoembolisation using cisplatin-lipiodol mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Tests in Healthy Korean Women Which Effects BI 409306 and a Birth-control Pill Have on Each Other
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Microgynon® 30|DRUG: BI 409306
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibacterial Mouthwash for Pharyngeal Gonorrhea Prevention
Status: RECRUITING
Conditions: Gonorrhea
Interventions: DRUG: Listerine Antiseptic Mouthwash Product|DRUG: Biotene Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery
Status: NOT_YET_RECRUITING
Conditions: Chronic Postsurgical Pain|Acute Pain|Emergency Surgery|Opioid|Postoperative Pain|Risk Factors
Interventions: OTHER: questionnaire|OTHER: phone call
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of Immunomaintenance Using POmalidomide With Elotuzumab afteR Second Autologous Transplant
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Varenicline Among HIV-infected Patients
Status: COMPLETED
Conditions: HIV Infections|Tobacco Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Rising Oral Doses of BI 691751 in Healthy Male Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of BV100 Administered as Single Intravenous Infusion to Subjects With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: BV100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erector Spinae Plane (ESP) Block Volunteer Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain Management
Interventions: OTHER: Erector Spinae Plane Block with 1.5% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Optimization in 3D Pulsed Dose Rate Brachytherapy for Patients With Locally Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Stage IB Cervical Cancer|Stage II Cervical Cancer|Stage III Cervical Cancer
Interventions: RADIATION: External Beam Radiation Therapy|RADIATION: PDR Brachytherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)
Status: TERMINATED
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Aripiprazole|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS in Treatment Resistant Depression
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Active Neuronetics rTMS stimulator|DEVICE: Inactive Neuronetics rTMS stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Gastric Ulcer Participants With or Without Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: TAK-438|DRUG: Lansoprazole|DRUG: TAK-438 Placebo|DRUG: Lansoprazole Placebo|DRUG: Bismuth-Containing Quadruple Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety LactiSal 1% Gel, LactSal 50 mg, Clotrimazole 100 mg Tablet in Treatment Vulvovaginal Candidiasis
Status: WITHDRAWN
Conditions: Vulvovaginal Candidiasis
Interventions: DEVICE: LactiSal vaginal gel 1%|DEVICE: LactiSal vaginal tablet 50mg|DRUG: Clotrimazole vaginal tablet 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-05089771 300mg|DRUG: PF-05089771 300 mg + pregabalin 300 mg|DRUG: Placebo|DRUG: pregabalin 300 mg|DRUG: ibuprofen 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolic Impact and Compliance of Controlled, Varying, Mediterranean Diets in Pre-Surgical Prostate Cancer Populations (PROVISIONS)
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Low fat diet|BEHAVIORAL: Lower carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator Asynchronies
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: OTHER: Muscle Pressure curve (Pmus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease
Interventions: GENETIC: Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase|DRUG: Rapamycin|OTHER: saline|DRUG: Rituxan|DRUG: Diphenhydramine|DRUG: Acetaminophen|DRUG: Lidocaine|DRUG: LMX 4 Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Levofloxacin as Prophylaxis After Allogeneic Stem Cell Transplantation (SCT)
Status: UNKNOWN
Conditions: Malignancy|Allogeneic Stem Cell Transplantation
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Cognitive-Motor Dual-Task Exercise and Exergaming on Balance, Functional Mobility, and Executive Function in Down Syndrome Children
Status: NOT_YET_RECRUITING
Conditions: Down Syndrome
Interventions: OTHER: cognitive motor dual task exercises|OTHER: exergaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Transferability of Skills From Robotic to Laparoscopic Simulation Platforms
Status: COMPLETED
Conditions: Surgical Simulation Education
Interventions: DEVICE: a laparoscopic simulator (Fundamentals of Laparoscopic Surgery (FLS), VT Medical Inc, Waltham, MA)|DEVICE: Mimic da Vinci robotic simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: SHR-1210 in Combination With Anlotinib in Patients With Advanced or Metastatic Esophageal Squamous Cell Cancer
Status: UNKNOWN
Conditions: SHR-1210|Anlotinib|Advanced Esophageal Squamous Cell Cancer
Interventions: DRUG: SHR-1210 plus Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of N1539 Following Bunionectomy Surgery
Status: COMPLETED
Conditions: Pain, Post-operative
Interventions: DRUG: N1539|DRUG: Intravenous Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mortality Reduction After Oral Azithromycin: Morbidity Study
Status: COMPLETED
Conditions: Childhood Mortality
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stapled Anastomosis Versus Hand-sewn for Neonate With Intestinal Atresia
Status: UNKNOWN
Conditions: Intestinal Atresia|Anastomotic Complication
Interventions: PROCEDURE: Endocutter stapler|PROCEDURE: suture material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy
Status: WITHDRAWN
Conditions: Hepatitis B Virus
Interventions: BIOLOGICAL: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT