pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors
Status: RECRUITING
Conditions: Psoriasis
Interventions: BEHAVIORAL: Mediterranean Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alendronate to Prevent Loss of Bronchoprotection in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Incomplete Abortion With 600 Mcg Oral Misoprostol Compared to Standard Surgical Treatment
Status: COMPLETED
Conditions: Incomplete Abortion
Interventions: DRUG: 600 mcg misoprostol|PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adjunctive Cilostazol in Acute Myocardial Infarction Patients
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: antiplatelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial)
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Dexmedetomidine|DRUG: Clonidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLT-PET Activity Change After Allogeneic Umbilical Cord Blood (UCB) Therapy in Cerebral Palsy
Status: WITHDRAWN
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Umbilical Cord Blood Infusion|OTHER: Active Rehabilitation|OTHER: Placebo Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures
Status: UNKNOWN
Conditions: Fractures, Bone|Deformity; Bone
Interventions: DEVICE: A treatment group that will watch a non-VR video via an iPad|DEVICE: A treatment group that will have headset on and will watch a non-VR video|DEVICE: A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|BEHAVIORAL: Cognitive Processing Therapy|DEVICE: Repetitive Transcranial Magnet Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency and Myofascial Pain Syndrome in Postpartum Pelvic Pain
Status: RECRUITING
Conditions: To be Approved by the Ethics Committee
Interventions: OTHER: Active Comparator: Experimental Group 1|OTHER: Experimental: Experimental Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Image-Guided Radiotherapy For Prostate Cancer: The HEIGHT Trial
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: RADIATION: SIMRT|RADIATION: HTIMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Advanced Solid Tumor Patients and in Combination With Fulvestrant in Patients With Advanced Breast Cancer
Status: RECRUITING
Conditions: PIK3CA Mutation|Solid Tumor, Adult|HER2-negative Breast Cancer|Breast Cancer|Metastatic Breast Cancer|Advanced Breast Cancer|Unresectable Solid Tumor
Interventions: DRUG: RLY-2608|DRUG: Fulvestrant|DRUG: Palbociclib 125mg|DRUG: Ribociclib 400mg|DRUG: Ribociclib 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hepatitis C Virus Infection With Generic Sofosbuvir/Ledipasvir in Iranian Patients
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: Sofosbuvir/Ledipasvir 12W|DRUG: Sofosbuvir/Ledipasvir plus Ribavirin 12W|DRUG: Sofosbuvir/Ledipasvir 24W|DRUG: Sofosbuvir/Ledipasvir plus Ribavirin 24W
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC Patients
Status: RECRUITING
Conditions: Lung Neoplasms|Lung Cancer, Nonsmall Cell|Adenocarcinoma of Lung|Squamous Cell Lung Cancer
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perfusion Index and Pleth Variability Index an Early Indicator of the Success of Brachial Plexus Block; Randomized Clinical Triall
Status: COMPLETED
Conditions: Perfusion Index and Pleth Variability Index an Early Indicator of the Success of Brachial Plexus Block; Randomized Clinical Trial
Interventions: OTHER: INTERSCALEN BLOCK APPLICATION WITH USG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Coronary Plaque Composition
Status: COMPLETED
Conditions: Coronary Atherosclerosis|Endothelial Dysfunction|Coronary Small Vessel Disease
Interventions: DEVICE: LipiScan/LipiScan IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease, Early Onset
Interventions: DEVICE: Theta-burst stimulation (TBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of the Perfusion Scanner in the Prediction of the Tumor Control of Patients With Hepatocellular Carcinoma Treated With Sorafenib.
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Perfusion Scanner
Interventions: OTHER: Scannographic evaluation of the tumor response performed with mRECIST criteria after 3 months of treatment with sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PASCAL Laser Versus ETDRS Laser Associated With Intravitreal Ranibizumab (IVR) Versus Only IVR for Proliferative Diabetic Retinopathy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Intravitreal Ranibizumabe|DRUG: panfotocoagulation (PASCAL)|DRUG: panfotocoagulation (PRP) single shoot (ETDRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Recruitment During Neck Flexion and Inspiratory Muscle Training
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilator Weaning|Respiratory Muscle Training
Interventions: OTHER: Quasi-Isometric Neck Flexion|OTHER: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Minipooled-IVIG in Primary Immunodeficiency Disease
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: OTHER: minipooled- Intravenous immunoglobulin(MP-IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Carotid Stent Design on Cerebral Embolization
Status: COMPLETED
Conditions: Stroke|Carotid Stenosis
Interventions: DEVICE: closed-cell stent (Xact stent)|DEVICE: Open-cell stent (Acculink carotid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adoptive Cell Therapy for B-Cell Cancers in Patients After Stem Cell Transplantation
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Allogeneic Cell Therapy w/ Tumor-derived Lypho
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Protein Metabolism in Healthy Older Subjects
Status: COMPLETED
Conditions: Malnutrition
Interventions: OTHER: Experimental protein powder sachet|OTHER: Control protein powder sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pilot Study to Evaluate the Efficacy and Safety of Quetiapine Fumarate Instant-Release (Seroquel IR) in Controlling Agitation and Aggressive Symptoms in the Acute Treatment of Patients With Schizophrenia
Status: UNKNOWN
Conditions: Acute Schizophrenia
Interventions: DRUG: Quetiapine fumarate|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre-surgical Detection of Clear Cell Renal Cell Carcinoma (ccRCC) Using Radiolabeled G250-Antibody
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: 124-Iodine-cG250 (124I-cG250)|PROCEDURE: CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First-In-Human PainCart Study for STR-324
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Placebo|DRUG: STR-324 Dose Level 1|DRUG: STR-324 Dose Level 2|DRUG: STR-324 Dose Level 3|DRUG: STR-324 Dose Level 4|DRUG: STR-324 Dose Level 5|DRUG: STR-324 Dose Level 6|DRUG: STR-324 Dose Level 7|DRUG: STR-324 Dose Level 8|DRUG: STR-324 Dose Level A|DRUG: STR-324 Dose Level B|DRUG: STR-324 Dose Level C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma
Interventions: BIOLOGICAL: Vigil|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Gemcitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irritable Bowel Syndrome (IBS) Treatment With H1-receptor Antagonists
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: ebastine|DRUG: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paced Dyssynchrony and Myocardial Perfusion IN apiCal Hcm
Status: TERMINATED
Conditions: Hypertrophic Cardiomyopathy
Interventions: OTHER: Asynchronous dual chamber pacing (DOO) with paced ventricular activation|OTHER: Asynchronous atrial pacing (AOO) with intrinsic ventricular activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination Methotrexate and Infliximab
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Infliximab and MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Intractable Cerebral Vasospasm
Status: COMPLETED
Conditions: SAH|Inhaled Nitric Oxide|Cerebral Ischemia|Vasospasm
Interventions: DRUG: Inhaled nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery
Status: UNKNOWN
Conditions: Uterus Disease
Interventions: PROCEDURE: mini invasive approach|PROCEDURE: Conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eccentrically Reinforced Resistance Training vs. Traditional Resistance Training in Sedentary Older Women
Status: COMPLETED
Conditions: Depression|Physical Functional Performance|Executive Function
Interventions: BEHAVIORAL: Eccentrically strengthened resistance exercise|BEHAVIORAL: Traditional resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin in Patients With Cirrhosis and Ascites
Status: RECRUITING
Conditions: Cirrhosis|Liver Failure
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Esophageal Temperature During PVI Using Q-DOT Micro
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal
Interventions: DEVICE: QDOT Micro ablation catheter|DEVICE: ST SF ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AABM to Decrease Problem Drinking and Impulsivity in Veterans With AUD: A Pilot Study
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: AABM Training|BEHAVIORAL: Sham Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil and Fentanyl in Dental Surgery (REFEDS)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Remifentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TeleRehab to Restore Upper Limb Function in People With Chronic TBI
Status: RECRUITING
Conditions: Traumatic Brain Injury|Upper Extremity Dysfunction|Disability Physical
Interventions: BEHAVIORAL: HAHE|BEHAVIORAL: Exergame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Varenicline on Smoking Cessation at the Acute Phase of an Exacerbation of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD Exacerbation|Smoking
Interventions: DRUG: Varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Booster Vaccination With COVID-19 Vaccine (Vero Cell),Inactivated From Different Manufactures for Prevention of COVID-19
Status: SUSPENDED
Conditions: COVID-19
Interventions: BIOLOGICAL: Experimental vaccine 1|BIOLOGICAL: Experimental vaccine 2|BIOLOGICAL: Experimental vaccine 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Interwoven Self-Expandable Nitinol Stent for Femropopliteal Arterial Occlusive Diseases
Status: NOT_YET_RECRUITING
Conditions: Femoropopliteal Occlusive Disease
Interventions: OTHER: Interwoven supera stent (IW; Supera Veritas®; Abbott Vascular, Santa Clara, CA, USA) .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial on the Effect of Retrograde Partial Bladder Fill on Time to Discharge and Overall Medical Staff Satisfaction
Status: COMPLETED
Conditions: Retrograde Bladder Fill
Interventions: PROCEDURE: retrograde bladder filling with 0.9% normal saline 250cc prior to removal of foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Ondansetron|DRUG: promethazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Chest Compression Depth Obtained Using the Smartphone Application as an Educational Tool With New Attachment Device
Status: UNKNOWN
Conditions: Basic Cardiac Life Support
Interventions: DEVICE: Grasp method|DEVICE: Armband-in-hand method|DEVICE: Armband-on-arm method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: HHHFNC|DEVICE: NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Platelet Activity for Cerebral Hemorrhage Treatment - DDAVP Proof of Concept
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: DDAVP injection (desmopressin acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incorporation of Patient Reported Outcomes Data in the Care of US Veterans With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: PRO data utilized|OTHER: PRO data not utilized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation
Status: COMPLETED
Conditions: Acute Respiratory Failure|Intubation Complication|Hypotension on Induction
Interventions: DRUG: Fluid Bolus|OTHER: No Fluid Bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Measure Drug Satisfaction of Patients With Schizophrenia After Switching From Risperidone to Paliperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oral Risperidone|DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Efficacy and Safety of Duac™Compared With Clindamycin Phosphate Gel in the Treatment of Mild to Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Duac™Once Daily Gel|DRUG: 1% clindamycin phosphate gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|HER2-negative Breast Cancer|Metastatic Castration-resistant Prostate Cancer (mCRPC)|Pancreatic Cancer|Platinum-resistant Ovarian Cancer (PROC)
Interventions: DRUG: NUV-1511
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study of BMS-986094 and Daclatasvir, With or Without Ribavirin for the Treatment of Patients With Chronic Hepatitis C
Status: WITHDRAWN
Conditions: Hepatitis C Virus
Interventions: DRUG: Daclatasvir|DRUG: Daclatasvir|DRUG: BMS-986094|DRUG: BMS-986094|DRUG: BMS-986094|DRUG: Ribavirin|DRUG: Placebo for BMS-986094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FIbrosis and Steatosis in Patients With Psychiatric Illness
Status: COMPLETED
Conditions: Severe Bipolar I Disorder (Diagnosis)|Bipolar I Disorder, Most Recent Episode Mixed, in Remission|Depression Psychotic Feature|Mood-Incongruent Delusion
Interventions: DIAGNOSTIC_TEST: Fibroscan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telehealth Parent Coaching to Improve Activity Participation for Young Children With ASD and SPD
Status: NOT_YET_RECRUITING
Conditions: Sensory Processing Disorder|Autism Spectrum Disorder
Interventions: BEHAVIORAL: parent coaching via telehealth|BEHAVIORAL: weekly self-learning materials and group discussion session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Ultrasound Screening of Heterotopic Ossification After Severe Neurological Trauma
Status: RECRUITING
Conditions: Heterotopic Ossification
Interventions: PROCEDURE: Ultrasound|PROCEDURE: CT scan|PROCEDURE: Clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Exploratory Study to Evaluate the Combination of Elotuzumab and Nivolumab With and Without Pomalidomide in Relapsed Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Pomalidomide|DRUG: Elotuzumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pocket-size Cardiovascular Ultrasound in Stroke
Status: COMPLETED
Conditions: Ischemic Attack, Transient|Transient Ischemic Attack|Stroke|Cerebrovascular Accident|Cerebrovascular Apoplexy|Apoplexy
Interventions: PROCEDURE: Bed-side pocket size ultrasound imaging|DEVICE: GE Ultrasound Vscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Colorectal Cancer Infection in Elective Surgery
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Intra-peritoneal antibiotic lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intraocular Bevacizumab (Avastin) for Rubeosis Iridis
Status: COMPLETED
Conditions: Glaucoma|Rubeosis Iridis
Interventions: DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101)
Status: TERMINATED
Conditions: Neoplasm Malignant|Epithelial Ovarian Cancer|Triple Negative Breast Cancer|Hormone Receptor Positive Breast Carcinoma|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: XL102|DRUG: Fulvestrant|DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE)
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma|Neoadjuvant Therapy|Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pomegranate Consumption by Poly-medicated Metabolic Syndrome Patients
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Pomegranate extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPA-FFA to Treat Hospitalised Patients With COVID-19 (SARS-CoV-2)
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: DRUG: Eicosapentaenoic acid gastro-resistant capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatments in Women Veterans With Insomnia and PTSD
Status: RECRUITING
Conditions: Insomnia|PTSD|Women Veterans
Interventions: BEHAVIORAL: Trauma-Informed CBT-I|BEHAVIORAL: PTSD Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Different Approaches in Robotic-Assisted Renal Surgery
Status: RECRUITING
Conditions: Renal Tumor
Interventions: PROCEDURE: Robotic-assisted laparoscopic partial nephrectomy (LPN) or laparoscopic nephrectomy (LN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cystoscopic Evaluation Predicting pT0 Urothelial Carcinoma of the Bladder
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: PROCEDURE: Radical Cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recognizing Pain Intensity in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Pain|Autonomic Nervous System Disease
Interventions: DIAGNOSTIC_TEST: cognitive assessment|OTHER: Cold Pressor Test|OTHER: digital sensor of Nociception Level Index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Exploratory Study of DS-8500a on Beta Cell Function Using Hyperglycemic Clamp
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DS-8500a|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Esophageal Motility Disorders
Status: COMPLETED
Conditions: Achalasia|Hypertensive LES
Interventions: PROCEDURE: Per Oral Endoscopic Myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Immunogenicity Study of Multiple Doses of Proposed Pegfilgrastim Biosimilar, INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.
Status: COMPLETED
Conditions: Immunogenicity|Healthy Volunteers
Interventions: COMBINATION_PRODUCT: INTP5|COMBINATION_PRODUCT: US Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Improvements of the Quality of Sleep With NOVANUIT® Triple Action in Healthy Volunteers With Sleep Disorders
Status: COMPLETED
Conditions: Sleep Disorder (Healthy Volunteers)
Interventions: DRUG: MELATONIN (MELATL07959)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Unexplained Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest|Long QT Syndrome|Brugada Syndrome|Catecholaminergi Polymorphic Ventricular Tachycardia|Idiopathic VentricularFibrillation|Early Repolarization Syndrome|Arrhythmogenic Right Ventricular Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcomes of Early Laparoscopic Cholecystectomy in Cases of Acute Cholecystitis
Status: UNKNOWN
Conditions: Acute Calculous Cholecystitis
Interventions: PROCEDURE: Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
Status: UNKNOWN
Conditions: Type 2 Diabetes Patients|Overweight and Obesity|Hyperglycaemia (Diabetic)
Interventions: DRUG: Liraglutide|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Formulation Bridging and Food Effect Study of PBI-200 in Healthy Volunteers
Status: COMPLETED
Conditions: Formulation Bridging|Food Effect
Interventions: DRUG: PBI-200 Tablet|DRUG: PBI-200 Capsule|DRUG: PBI-200 Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natreon Healthy Skin Study - PrimaVie Supplement
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: PrimaVie Herbal Supplement 125|DIETARY_SUPPLEMENT: PrimaVie Herbal Supplement 250|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Bone Regenerated With Guided Bone Regeneration (GBR) Using Polymethylmethacrylate (PMMA) Membrane
Status: NOT_YET_RECRUITING
Conditions: Horizontal Ridge Deficiency
Interventions: PROCEDURE: guided bone regeneration (GBR).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Encorafenib|DRUG: Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"
Status: COMPLETED
Conditions: Excessive Physical Exercise, Unspecified
Interventions: DIETARY_SUPPLEMENT: Arginine antioxidant supplements|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Paricalcitol Capsules, 4 mcg Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paricalcitol Capsules, 4 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Articaine and Mepivacaine Without Palatal Injection in Pain Assessment During Maxillary Teeth Extraction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: buccal infiltration of 4% Articaine with Epinephrine|DRUG: buccal infiltration of 2% Mepivacaine with Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory Infertile Women With Spleen-kidney Yang Deficiency PCOS
Status: UNKNOWN
Conditions: PCOS|Infertility, Female
Interventions: DRUG: Letrozole|DEVICE: acupuncture|OTHER: Governor vessel moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Lego Robot Programming Intervention for Enhancing Older Adult Cognitive Health
Status: RECRUITING
Conditions: Cognitive Inferential Ability
Interventions: BEHAVIORAL: Lego Robot Programming Active Challenges|BEHAVIORAL: Lego Robot Programming Procedural Methods|BEHAVIORAL: Board Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: (dexlan+amox+clar+metr)+(dexlan+amox)|DRUG: dexlan+clarith+amox+metro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Endostar in Patients With Carcinoma of the Head and Neck
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: American Ginseng Treatment for Multiple Sclerosis Related Fatigue
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: American ginseng extract HT-1001|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Finding Study
Status: UNKNOWN
Conditions: Gram-Positive Bacterial Infections
Interventions: DRUG: Daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Neural Basis of Analogical Reasoning
Status: COMPLETED
Conditions: Frontotemporal Dementia|Progressive Supranuclear Palsy|Healthy Subjects
Interventions: DEVICE: transcranial magnetic stimulation|OTHER: MRI imaging|OTHER: EEG recording|BEHAVIORAL: Neuropsychological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Fluoxetine in Healthy Adult Subjects Under Fasting Condition
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Fluoxetine 10 mg capsules|DRUG: Prozac® 10 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SAVINO (Saypha® Volume LIdocaine in Nasolabial FOlds)
Status: COMPLETED
Conditions: Moderate to Severe Nasolabial Folds
Interventions: COMBINATION_PRODUCT: Saypha Volume Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
Status: COMPLETED
Conditions: Candidiasis, Esophageal|HIV Infections
Interventions: DRUG: Itraconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Ovarian Cancer
Status: TERMINATED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery
Status: TERMINATED
Conditions: Laparoscopic Surgery
Interventions: DRUG: N1539|DRUG: N1539|DRUG: N1539|DRUG: Ketorolac Tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Lozenges and Their Effect on Postoperative Sore Throat Syndrome
Status: COMPLETED
Conditions: Sore Throat|Post-Operative Sore Throat
Interventions: DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute Agitation
Status: COMPLETED
Conditions: Agitated; State, Acute Reaction to Stress|Agitation,Psychomotor
Interventions: OTHER: Music
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pomalidomide, Ixazomib, and Dexamethasone With or Without Intensification by Cyclophosphamide in Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: MLN9708|DRUG: Pomalidomide 4 MG Oral Capsule|DRUG: Dexamethasone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Spinal Cord Stimulation in Patients With Spinal Cord Stimulation
Status: NOT_YET_RECRUITING
Conditions: Disorder of Consciousness|Spinal Cord Stimulation
Interventions: PROCEDURE: SCS Stimulation|PROCEDURE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Ingestion Prior to Surgery (CIPS)
Status: RECRUITING
Conditions: Urologic Surgical Procedures|Carbohydrate Loading|Preoperative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Alveolar Recruitment Protocol After Cardiac Surgery
Status: COMPLETED
Conditions: Ventilator Induced Lung Injury|Cardiac Disease|Acute Lung Injury
Interventions: OTHER: Intensive Alveolar Recruitment|OTHER: Moderate Alveolar Recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Beer on Gut Microbiota and Biochemical Outcomes: Alcohol Impact.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Beer with 5.20 % alcohol|DIETARY_SUPPLEMENT: Non-alcoholic beer with 0.45 % alcohol|DIETARY_SUPPLEMENT: Non-alcoholic beer with 0.00 % alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: Rivaroxaban|DRUG: Acetylsalicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Revascularization Surgery|OTHER: Supervised exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of DbXell in the Treatment of Subjects With Mildly Uncontrolled Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: DbXell|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Stress-predominant Mixed Urinary Incontinence
Status: UNKNOWN
Conditions: Mixed Urinary Incontinence
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tadalafil in Men With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DRUG: Tadalafil 5 mg|DRUG: Placebo tablet|DRUG: Tamsulosin|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Versus High-Dose Trivalent Inactivated Flu Vaccine in Pediatric Acute Lymphoblastic Leukemia Patients
Status: COMPLETED
Conditions: Pediatric Patients With Acute Lymphoblastic Leukemia
Interventions: DRUG: High-dose trivalent inactivated influenza vaccine|DRUG: Standard dose trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Omentopexy With Glubran®2 for Reducing Complications After Sleeve Gastrectomy
Status: COMPLETED
Conditions: Obesity With BMI >35
Interventions: DEVICE: omentopexy with cyanoacrilate glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Persistence and Immune Response to a Booster Dose of MenACWY
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Novartis Meningococcal (MenACWY-CRM) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BCD-135 in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Melanoma|NSCLC|Renal Cell Carcinoma|Bladder Cancer
Interventions: DRUG: BCD-135
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nifedipine Plus Magnesium Sulfate Versus Magnesium Sulfate for Very Early Preterm Tocolysifs
Status: RECRUITING
Conditions: Threatened Preterm Labor
Interventions: DRUG: Nifedipine 20 Mg|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Group Intervention for Promoting Health-related Habits (LEV-G)
Status: RECRUITING
Conditions: Life Style|Health-Related Behavior|Disabilities Mental|Disability Physical|Acceptability of Health Care
Interventions: BEHAVIORAL: Lev-g
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial Using CD133 Enriched Bone Marrow Cells Following Primary Angioplasty for Acute Myocardial Infarction
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: CD133+ infusion|OTHER: placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Exercise-induced Lipolysis
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin Oral|DRUG: Metformin local in AT|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Eductyl® Versus Placebo for Treatment of Dyschesia
Status: COMPLETED
Conditions: Dyschesia
Interventions: DRUG: Eductyl suppository|DRUG: Placebo suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Phototoxity of Atralin (Tretinoin) Gel, 0.05%
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atralin (tretinoin) Gel, 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Sleep and Quality of Life in Patients With Glycogen Storage Disease on Standard Versus Modified Uncooked Cornstarch
Status: COMPLETED
Conditions: Glycogen Storage Disease Type IA|Glycogen Storage Disease Type IB|Glycogen Storage Disease Type III|Glycogen Storage Disease Type 0
Interventions: DIETARY_SUPPLEMENT: Glycosade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Oseltamivir (Tamiflu) for Treatment of Influenza in Immunocompromised Participants.
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: oseltamivir|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of α-galactosidase in Treating Gas-related Symptoms in Children
Status: COMPLETED
Conditions: Gas Pain Related Intake
Interventions: DIETARY_SUPPLEMENT: α-galactosidase|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT