pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
Status: TERMINATED
Conditions: Adenotonsillectomy|Post-operative Analgesia|Opioid Use
Interventions: DRUG: Oxycodone|DRUG: Ibuprofen|DRUG: Acetaminophen|OTHER: Opioid disposal pouch|OTHER: Opioid disposal education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Dapsone 7.5 % gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery
Status: TERMINATED
Conditions: Postoperative Pain Management
Interventions: DRUG: EXPAREL and bupivacaine HCl|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mefloquine as Prophylaxis Against COVID-19: A Placebo-control, Randomized Clinical Trial
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Mefloquine as a prophylaxis against SARS-Cov-2 infection in household contacts of COVID 19 confirmed cases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Application of 3D Printing Technique in Small Pulmonary Nodule Localization
Status: COMPLETED
Conditions: Lung Neoplasm|Thoracic Surgery, Video-Assisted
Interventions: DEVICE: template-guided localization|OTHER: CT-guided localization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine
Status: COMPLETED
Conditions: Migraine|Common Migraine|Classic Migraine|Headache
Interventions: DRUG: topiramate, propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Ublituximab in Participants With Relapsing Forms of Multiple Sclerosis (RMS) ( ULTIMATE 1 )
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis (RMS)
Interventions: BIOLOGICAL: Ublituximab|DRUG: Teriflunomide|DRUG: Oral Placebo|DRUG: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
Status: RECRUITING
Conditions: Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy|Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy|Wild-Type Transthyretin Cardiac Amyloidosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Relationship Between LRG and Periodontal Disease
Status: COMPLETED
Conditions: Periodontitis|Acute-Phase Response|Inflammation
Interventions: OTHER: Non-surgical periodontal treatment|OTHER: Oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Serologic Profile of SARS CoV2 in COVID-19 Patients With Systemic Diseases
Status: UNKNOWN
Conditions: SARS-CoV Infection|Systemic Disease|Systemic Lupus Erythematosus|Sjogren's Syndrome|Sarcoidosis|Inflammatory Myopathy|Behçet Disease|Rheumatoid Arthritis|Spondyloarthritis
Interventions: DIAGNOSTIC_TEST: Serological test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Mandibular Procedures
Status: COMPLETED
Conditions: Anesthesia, Dental
Interventions: DRUG: Phentolamine Mesylate (NV-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of Metformin With Carboplatin/Paclitaxel Chemotherapy in Patients With Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Metformin|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Ampion in Patients With Prolonged Respiratory Symptoms Due to COVID-19 (Long COVID)
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Ampion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: TLC599|DRUG: DSP|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Compare On-Demand Treatment To A Prophylaxis Regimen Of BeneFIX In Subjects With Moderately Severe to Severe Hemophilia B
Status: COMPLETED
Conditions: Hemophilia B
Interventions: BIOLOGICAL: Nonacog alfa|BIOLOGICAL: Nonacog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Daclizumab in Patients With Active, Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Daclizumab (Anti-CD25 Humanized Monoclonal Antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of BGG492 in Individuals With Refractory Partial Seizures Undergoing Inpatient Evaluation for Epilepsy Surgery
Status: COMPLETED
Conditions: Seizures|Epilepsy
Interventions: DRUG: Investigational new drug, company code: BGG492|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Virtual Reality Before Oocytes Retrieval on Anxiety and Pregnancy Rate
Status: UNKNOWN
Conditions: Anxiety|in Vitro Fertilization|Virtual Reality
Interventions: DEVICE: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Real World Data Study Assessing The Persistency Of Xalacom And The Other Fixed Dose Combination Products, Duotrav And Ganfort, In The United Kingdom
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: XALACOM|DRUG: Duotrav|DRUG: Ganfort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ramipril for the Treatment of Oligospermia
Status: TERMINATED
Conditions: Oligospermia|Teratospermia|Asthenozoospermia|Male Infertility
Interventions: DRUG: Ramipril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Uneven Terrain Surface to Improve Locomotor Robustness in People With Amputation
Status: RECRUITING
Conditions: Amputation
Interventions: OTHER: Gait practice on an uneven terrain surface|OTHER: Gait practice on a flat terrain surface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Vs Chemomechanical Method For Calcium Hydroxide Removal
Status: COMPLETED
Conditions: Necrotic Pulp|Chronic Apical Periodontitis
Interventions: OTHER: Mechanical Method|OTHER: Chemomechanical Method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extrahepatic Bile Duct Adenocarcinoma, Biliary Type|Gallbladder Adenocarcinoma, Biliary Type|Metastatic Pancreatic Adenocarcinoma|Recurrent Cholangiocarcinoma|Recurrent Gallbladder Carcinoma|Recurrent Hepatocellular Carcinoma|Recurrent Intrahepatic Cholangiocarcinoma|Recurrent Pancreatic Carcinoma|Stage III Gallbladder Cancer AJCC V7|Stage III Hepatocellular Carcinoma AJCC v7|Stage III Intrahepatic Cholangiocarcinoma AJCC v7|Stage III Pancreatic Cancer AJCC v6 and v7|Stage IIIA Gallbladder Cancer AJCC v7|Stage IIIA Hepatocellular Carcinoma AJCC v7|Stage IIIB Gallbladder Cancer AJCC v7|Stage IIIB Hepatocellular Carcinoma AJCC v7|Stage IIIC Hepatocellular Carcinoma AJCC v7|Stage IV Gallbladder Cancer AJCC v7|Stage IV Hepatocellular Carcinoma AJCC v7|Stage IV Pancreatic Cancer AJCC v6 and v7|Stage IVA Gallbladder Cancer AJCC v7|Stage IVA Hepatocellular Carcinoma AJCC v7|Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7|Stage IVB Gallbladder Cancer AJCC v7|Stage IVB Hepatocellular Carcinoma AJCC v7|Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7|Unresectable Gallbladder Carcinoma|Unresectable Pancreatic Carcinoma
Interventions: BIOLOGICAL: Durvalumab|DRUG: Guadecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Depression|Parenting|Parent-Child Relations|Child Development
Interventions: BEHAVIORAL: MoodGym|BEHAVIORAL: Social Media-Based Parenting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study, to Assess the Effect of Repeat-dose Inhaled Indacaterol Maleate (300 μg) on Dynamic and Static Lung Hyperinflation, Subjective Breathlessness and Health Status in Patients With Chronic Obstructive Pulmonary Disease(COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 300μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Relapsing-remitting Multiple Sclerosis
Interventions: BEHAVIORAL: GEMS Plus|BEHAVIORAL: GEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Coagulation Cascade in Idiopathic Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis|IPF|Interstitial Lung Disease
Interventions: DRUG: Dabigatran|RADIATION: FDG PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimal Duration of Anticoagulation in Deep Venous Thrombosis
Status: COMPLETED
Conditions: Deep Vein Thrombosis of Lower Limb|Lower Extremity Deep Venous Thrombosis Recurrent
Interventions: DRUG: Sodium warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Umbilical Cord Milking on Iron Related Health Outcomes for Cesarean-Delivered Infants
Status: COMPLETED
Conditions: Anemia, Iron-Deficiency
Interventions: PROCEDURE: Umbilical cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: STEP: Building Trauma Resilience Among Nurses and Personal Support Workers During and Beyond COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress|Trauma|Mental Health Issue|Healthcare Workers
Interventions: BEHAVIORAL: Supportive Trauma Exposure Preparation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Observational Epidemiologic Study of Maraviroc's Safety
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Maraviroc along with an optimized background antiretroviral drug regimen|DRUG: Optimized background antiretroviral drug regimen without maraviroc
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine Added to Ropivacaine Single Shot vs Continuous Interscalene Nerve Block
Status: RECRUITING
Conditions: Anesthesia|Shoulder Pain|Post Operative Pain
Interventions: DRUG: single shot interscalene brachial plexus block group with dexmedetomidine added to ropivacaine group|DRUG: continuous interscalene brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PRO 140 SC as Single Agent Maintenance Therapy in Virally Suppressed Subjects With CCR5-tropic HIV-1 Infection
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: PRO 140 (350 mg)|DRUG: PRO 140 (525 mg)|DRUG: PRO 140 (700 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-ablative Radiofrequency and Low Intensity Shock Wave Therapy in Fibrotic Plaque in Men With Peyronie's Disease
Status: RECRUITING
Conditions: Peyronie Disease
Interventions: DEVICE: Non-ablative Radiofrequency|DEVICE: Low-intensity Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Iron on Postoperative Fatigue Upon Coronary Artery Bypass Graft Patients
Status: TERMINATED
Conditions: Fatigue
Interventions: DRUG: Placebo|DRUG: Polysaccharide iron complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAKE IT CLEAN, Impact of Pocket Revision on the Rate of Infection and Other Complications in Patients Requiring Pocket Manipulation for Generator Replacement and/or Lead Replacement or Revision: A Prospective Randomized Study
Status: COMPLETED
Conditions: Infection
Interventions: PROCEDURE: ICD/pacemaker pocket revision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Corticalisation After Femoral Nail Dynamization in Hypertrophic Non-unions
Status: COMPLETED
Conditions: Pseudoarthrosis of Bone|Implant Breakage
Interventions: PROCEDURE: exchange nailing with larger, thicker nail crossing corticalization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib for Patients Achieving Complete Molecular Response for Cure D-NewS Trial
Status: UNKNOWN
Conditions: Myelogenous Leukemia, Chronic, Chronic Phase
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAbR Plus Ipilimumab Plus Nivolumab in Metastatic Melanoma Patients
Status: WITHDRAWN
Conditions: Melanoma|Metastatic Melanoma
Interventions: RADIATION: SAbR|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Dementia of Alzheimer Type|Amnestic Mild Cognitive Impairment
Interventions: DEVICE: High level of signal manipulation|DEVICE: Low level of signal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Migraine Medication Effects on Urinary Symptoms
Status: ENROLLING_BY_INVITATION
Conditions: Overactive Bladder|Bladder Pain Syndrome|Migraine Disorders|Overactive Bladder Syndrome|Overactive Detrusor|Migraine|Interstitial Cystitis
Interventions: DRUG: Ubrogepant|DRUG: Rimegepant|DRUG: Atogepant|DRUG: Eptinezumab|DRUG: Fremanezumab|DRUG: Galcanezumab|DRUG: Erenumab|DRUG: Botulinum toxin A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity, Safety, Tolerability of a Plant-made H5 Virus-like-particle (VLP) Influenza Vaccine.
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections
Interventions: BIOLOGICAL: Low dose of H5 VLP vaccine + Alhydrogel|BIOLOGICAL: Med dose of H5 VLP vaccine + Alhydrogel|BIOLOGICAL: High dose of H5 VLP vaccine + Alhydrogel|BIOLOGICAL: Low dose of H5 VLP vaccine + GLA-SE|BIOLOGICAL: High dose of H5 VLP vaccine + GLA-SE|BIOLOGICAL: Placebo comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Malignant Neoplasm in the Brain|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Copanlisib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)
Status: COMPLETED
Conditions: Biliary Tract Cancer|Cholangiocarcinoma|Gallbladder Cancer
Interventions: DRUG: M7824
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson
Status: COMPLETED
Conditions: Idiopathic Parkinson Disease|Parkinson's Disease and Parkinsonism
Interventions: GENETIC: Adipose-derived stromal vascular fraction cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Brain Plasticity in Premature Infants at School Age After Cognitive Remediation
Status: UNKNOWN
Conditions: Premature Childbirth
Interventions: DEVICE: Magnetic Resonance Imaging (MRI) 3 tesla
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)
Status: RECRUITING
Conditions: Depression, Anxiety|Distress, Emotional
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Morphine|DRUG: Morphine plus dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Hydroxytyrosol From Olive Watery Extract Supplements
Status: COMPLETED
Conditions: Biological Availability
Interventions: DIETARY_SUPPLEMENT: Oliphenolia® bitter|DIETARY_SUPPLEMENT: Oliphenolia®|DIETARY_SUPPLEMENT: La Vialla Extra Virgin Olive Oil containing 5 mg hydroxytyrosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients
Status: ENROLLING_BY_INVITATION
Conditions: Heart Transplantation
Interventions: DRUG: Thymoglobulin|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Lidocaine Spray Versus Vaginal Dinoprostone in IUD Insertion
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: lidocaine spray|DRUG: vaginal dinoprostone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab for the Treatment of Refractory Behcet's Uveitis
Status: TERMINATED
Conditions: Behcet Syndrome|Uveitis
Interventions: BIOLOGICAL: Tocilizumab (TCZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of GLB-COV2-043 as a COVID-19 Vaccine Booster
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: GLB-COV2-043|DRUG: BNT162b2/COMIRNATY®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Lithium Carbonate in the Treatment of Chronic Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Wellness Behaviors as a Function of Oxytocin vs Placebo
Status: COMPLETED
Conditions: Sustained Positive Emotions|Sustained Positive Behavior Change
Interventions: DRUG: Oxytocin|DRUG: Placebo (for oxytocin)|BEHAVIORAL: Lovingkindness Meditation|BEHAVIORAL: Mindfulness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Weight Gain|Eating Disorders|Perinatal Problems|Binge Eating|Craving
Interventions: BEHAVIORAL: Single-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Striatal Cholinergic System in the Pathophysiology of Dystonia
Status: COMPLETED
Conditions: Dystonia
Interventions: RADIATION: PET (Positron Emission Tomography) imaging|OTHER: MRI : Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a Decision Support System for People With Diabetes Who Use Multiple Daily Insulin Injections- Feasibility and Proof of Concept Studies
Status: RECRUITING
Conditions: Type1diabetes
Interventions: DEVICE: DreaMed Advisor Pro DSS-MDI algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
Status: RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Ruxolitinib Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Age-Related Macular Degeneration (AMD) Treatment With Rheopheresis Trial
Status: COMPLETED
Conditions: Dry Age Related Macular Degeneration
Interventions: DEVICE: Rheopheresis / double filtration plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.
Status: UNKNOWN
Conditions: Aphasia|Stroke
Interventions: DRUG: Wait first, then levetiracetam|DRUG: Levetiracetam first, then wait
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG PET/CT-based Prognostic Model for Predicting Outcome in Patients With Diffuse Large B-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DEVICE: 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HemORL: Monocentric, Prospective, Comparative Study on the Use of a Haemostatic Vacuum Device During Tonsillectomy in Children
Status: UNKNOWN
Conditions: Tonsillectomy|Hemorrhage|Postoperative Complications
Interventions: DEVICE: Vacuum device|PROCEDURE: Conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Insulin Secretory Capacity in Insulin-independent Pancreas-Kidney Recipients Compared to Controls
Status: UNKNOWN
Conditions: Kidney Transplantation|Pancreas Transplantation
Interventions: OTHER: hyperglycemic clamp test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Return to Work - Will Brief Intervention Reduce Opioid-induced Back Pain?
Status: UNKNOWN
Conditions: Opioid Dependence|Low Back Pain|Opioid Use
Interventions: BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual Environments
Status: COMPLETED
Conditions: Cerebrovascular Accident|Hemiparesis|Hemiplegia
Interventions: BEHAVIORAL: HAS Training|BEHAVIORAL: HAT training|BEHAVIORAL: Bimanual Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autism Spectrum Disorders: Double Blind Randomized Placebo-control Active Pilot Study of Transcranial Magnetic Stimulation Applied to the Superior Temporal Sulcus
Status: RECRUITING
Conditions: Autism Spectrum Disorders
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: MRI|DEVICE: Neuronavigation|DEVICE: Eye-tracking|GENETIC: Salivary samples|OTHER: Clinical scales
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race
Status: COMPLETED
Conditions: Pre Diabetes|Obesity
Interventions: BEHAVIORAL: Weight Loss|DIETARY_SUPPLEMENT: Egg Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP)
Status: TERMINATED
Conditions: Acne|Post Inflammatory Hyperpigmentation
Interventions: DRUG: Liftactiv B3|OTHER: Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BK1301 (DTaP Vaccine) as a Booster in Adolescents
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP vaccine, BK1301)|BIOLOGICAL: Adsorbed Diphtheria-Tetanus Combined Toxoid (DT toxoid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Nurse-delivered Cognitive Behaviour Therapy on Adherence and Depressive Symptoms in HIV Infected Persons of South Korea
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer
Status: RECRUITING
Conditions: Hormone Sensitive Metastatic Prostate Cancer|DNA Damage Repair Deficiency|Chemotherapy Effect|Chemotherapeutic Toxicity
Interventions: DRUG: Docetaxel|DRUG: Prednisolone Acetate|DRUG: Platinum-based drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Rising Dose of BI 1181181 Given Orally in Young Healthy Male and Elderly Healthy Male/Female Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Matching placebo|DRUG: BI 1181181 healthy elderly|DRUG: BI 1181181 Healthy young
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Pregnancy Complications
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Tian Wang Bu Xin Dan Hydrogel Patch in Preventing Postoperative Delirium in Elderly Patients
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: DRUG: modified Tian Wang Bu Xin Dan hydrogel patch|OTHER: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Education Intervention on Vaccination Adherence Among Inflammatory Bowel Disease (IBD) Patients
Status: COMPLETED
Conditions: Crohn Disease (CD)|Ulcerative Colitis (UC)|Indeterminate Colitis
Interventions: OTHER: Vaccine Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin
Status: UNKNOWN
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: BIOLOGICAL: CG0070|BIOLOGICAL: Pembrolizumab Injection|OTHER: n-dodecyl-B-D-maltoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pedunculopontine Nucleus Stimulation for Gait Disorders in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Low frequency DBS of the pedunculopontine nucleus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Serious Games to Improve Social Skills in Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Autism
Interventions: BEHAVIORAL: Intervention Video Game|BEHAVIORAL: Placebo Control Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: clınıcal Effects of High-flow Nasal Oxygen Use ın gerıatrıc patıents
Status: UNKNOWN
Conditions: Biliary Obstruction|Oddi's Sphincter Constriction|Biliary Stones
Interventions: DEVICE: HİGH-FLOW NASAL OXYGEN USE (HFNO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Corneal WFG Versus AF Trans PRK in Myopic Patients With High Corneal HOA
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: corneal WFG group|PROCEDURE: aberration free group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Molecular Evaluation of Childern With Familial Meditterranean Fever and Their Siblings
Status: UNKNOWN
Conditions: Familial Mediterranean Fever
Interventions: DIAGNOSTIC_TEST: CBC with differential ,ESR ,CRP, Amyloid level , FMF gene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Romidepsin in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors
Status: TERMINATED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Metastatic Gastrointestinal Carcinoid Tumor|Pancreatic Polypeptide Tumor|Pulmonary Carcinoid Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Regional Gastrointestinal Carcinoid Tumor|Somatostatinoma
Interventions: DRUG: romidepsin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidimensional Treatment Foster Care for Adolescents
Status: WITHDRAWN
Conditions: Adolescent Behaviour|Family Functioning
Interventions: BEHAVIORAL: Multidimensional Treatment Foster Care|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes
Status: SUSPENDED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Post Cytotoxic Therapy|Acute Myeloid Leukemia With Multilineage Dysplasia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Myeloproliferative Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Raltitrexed-based Transarterial Chemoembolisation(TACE)for Colorectal Cancer Liver Metastases
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Raltitrexed|DRUG: Oxaliplatin|DRUG: lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Desipramine in Small Cell Lung Cancer and Other High-Grade Neuroendocrine Tumors
Status: TERMINATED
Conditions: Small Cell Lung Cancer (SCLC)|Neuroendocrine Tumors
Interventions: DRUG: Desipramine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory-Cognitive Training to Optimize Outcomes for Older CI Users
Status: RECRUITING
Conditions: Hearing Loss|Deafness
Interventions: BEHAVIORAL: Auditory-Cognitive Training|BEHAVIORAL: Non-auditory Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Cytarabine|DRUG: Gemtuzumab Ozogamicin|DRUG: Daunorubicin Hydrochloride|DRUG: Fludarabine Phosphate|DRUG: Idarubicin Hydrochloride|DRUG: Mitoxantrone Hydrochloride|DRUG: Etoposide|DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virus-specific Activated T Lymphocytes From a Donor in Hematopoietic Progenitor Transplanted Patients
Status: COMPLETED
Conditions: CMV Viremia|Immunosuppression-related Infectious Disease
Interventions: DRUG: Activated T-Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Quasi-experimental Evaluation of the Malezi Program in Tanzania
Status: COMPLETED
Conditions: Child Development|Father-Child Relations|Knowledge, Attitudes, Practice|Safety Issues
Interventions: BEHAVIORAL: RMV-ECD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study on the Efficacy and Gut Microbiota of Berberine and Probiotics in Patients With Newly Diagnosed Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: 1. Berberine hydrochloride tablets ; 2. ProMetS probiotics powder|DRUG: 1. Berberine placebo tablets ; 2. ProMetS probiotics powder|DRUG: 1. Berberine hydrochloride tablets; 2. Probiotics placebo powder|DRUG: 1. Berberine placebo tablets; 2. Probiotics placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Crossover Study of MK0893 in Patients With Type 2 Diabetes (0893-019 AM4)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK0893|DRUG: MK0893-matched Placebo|DRUG: Propranolol Hydrochloride (HCL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants With Generalized Myasthenia Gravis (gMG)
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis|gMG
Interventions: DRUG: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ulnar Nerve Injury Localization on Sleep Quality in Patients With Ulnar Nerve Entrapment Neuropathy
Status: COMPLETED
Conditions: Ulnar Neuropathies
Interventions: DIAGNOSTIC_TEST: EMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Compare the PK, PD, Safety & Immunogenicity of ADL-018 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ADL-018|BIOLOGICAL: US-licensed XOLAIR|BIOLOGICAL: EU-Approved XOLAIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Pharmacokinetics (PK), Safety, Tolerability of SR419 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SR419 capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction in Number of Botox Injections for Urgency Urinary Incontinence
Status: RECRUITING
Conditions: Urgency Urinary Incontinence
Interventions: PROCEDURE: Standard of care (15 Botox injections)|PROCEDURE: Experimental Arm (5 Botox injections)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Focused Suicide Prevention Strategy for Youth Presenting to the Emergency Department With Suicide Related Behaviour
Status: RECRUITING
Conditions: Suicide|Suicide Prevention|Suicidal Ideation|Self-Injurious Behavior|Behavioral Symptoms|Suicide, Attempted|Suicide and Self-harm
Interventions: BEHAVIORAL: SAFE Intervention|BEHAVIORAL: NAV (Telephone Navigation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial on Efficacy and Safety of Concurrent and Adjuvant Chemotherapy for the Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: concurrent chemotherapy with cisplatin|DRUG: concurrent chemotherapy with docetaxel|RADIATION: pelvic radiotherapy|RADIATION: brachytherapy|DRUG: adjuvant chemotherapy with cisplatin and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular Vessels Density Before and After PRP in Patients With Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: PRP
Interventions: OTHER: PRP was done using visulas green laser machine (Carl Zeiss Meditec AG Geoschwitzer Str. 51-52,07745 jena, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "IONTOPHORESIS vs. PHONOPHORESIS" for Treatment of Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: PROCEDURE: Iontophoresis Intervention|PROCEDURE: Phonophoresis|PROCEDURE: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Respiratory Muscle Training in People Who Have Had COVID-19 Disease
Status: COMPLETED
Conditions: Covid19|Respiratory Muscle Training|Respiratory Function Test|Quality of Life|Psychosocial Factor
Interventions: OTHER: Inspiratory muscle training group|OTHER: Inspiratory muscle training placebo group|OTHER: Inspiratory + expiratory muscle training group|OTHER: Inspiratory + expiratory muscle training placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence With Clinical Endpoint Study of Fluticasone Propionate 100 mcg and Salmeterol 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 mcg Inhalation Powder/GSK in Patients With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate 100 mcg and Salmeterol 50 mcg inhalation Powder/Respirent Pharmaceuticals|DRUG: ADVAIR DISKUS® 100/50 mcg inhalation powder pre-dispensed/GSK|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Development and Evaluation of SM-ART Intervention (SM-ART)
Status: COMPLETED
Conditions: Perinatal Depression|Resilience|Anxiety|Marital Conflict
Interventions: BEHAVIORAL: SM-ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VRC 320: A Phase I, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA090-00-VP, Administered Via Needle and Syringe or Needle-free Injector, PharmaJet, inHealthy Adults
Status: COMPLETED
Conditions: Prevention of Zika Infection|Zika-Specific Immune Response
Interventions: BIOLOGICAL: VRC-ZKADNA090-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin in Heart Failure Without Diabetes
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: Metformin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Chest Pain Imaging in the ED With the Combine CCTA and CT Perfusion
Status: COMPLETED
Conditions: Chest Pain
Interventions: DIAGNOSTIC_TEST: SPECT Imaging Test at Baptist hospital|DIAGNOSTIC_TEST: CT Angiography and CT myocardial perfusion at West Kendall Baptist Hospital|DIAGNOSTIC_TEST: SPECT Imaging Test at West Kendall Baptist Hospital
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Citrus Extract on Gastrointestinal Health
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Citrus extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Hip Scope Fascia-iliaca (FI) Block Study
Status: COMPLETED
Conditions: Hip Dysplasia|Femoroacetabular Impingement|Acetabular Labrum Tear
Interventions: DRUG: ropivicaine|DRUG: clonidine|DRUG: Epinephrine|DRUG: Noropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI
Status: UNKNOWN
Conditions: Secondary Hyperparathyroidism Due to Renal Causes|Chronic Kidney Diseases|Vitamin D Deficiency|Stage 5 Chronic Kidney Disease
Interventions: DRUG: Calcifediol Oral Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Zostavax Vaccination in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Varicella Zoster
Interventions: DRUG: Zostavax (varicella zoster virus) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION