pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cardiovascular Improvements With MV ASV Therapy in Heart Failure
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure|Sleep Disordered Breathing
Interventions: DEVICE: MV ASV|DRUG: Optimized Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Gemcitabine + Cisplatin +/- Iressa Bladder CCT
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Body-functionality Intervention for Body Image in Individuals With Skin Conditions
Status: COMPLETED
Conditions: Body Image|Psychological Distress|Dermatologic Disease|Quality of Life
Interventions: BEHAVIORAL: Expand your horizons: More than my skin|BEHAVIORAL: Creative writing activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: lebrikizumab|DRUG: montelukast [Singulair]|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Waveform Analysis for Thoracic Epidural Blocks
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Interventions: DEVICE: EWA through the needle|DEVICE: EWA through the catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PATH Partnering to Achieve Tobacco-free Health
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Acceptance & Commitment Therapy (ACT)|OTHER: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antibiotic Dosing in Pediatric Intensive Care
Status: RECRUITING
Conditions: Pharmacokinetics|Amoxicillin-clavulanate|Piperacillin-tazobactam|Vancomycin|Teicoplanin|Meropenem|Ciprofloxacin|Amikacin
Interventions: PROCEDURE: blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care|PROCEDURE: blood sampling in patients receiving piperacilline-tazobactam as part of routine clinical care.|PROCEDURE: blood sampling in patients receiving vancomycin as part of routine clinical care.|PROCEDURE: blood sampling in patients receiving teicoplanin as part of routine clinical care.|PROCEDURE: blood sampling in patients receiving meropenem as part of routine clinical care.|PROCEDURE: blood sampling and urine smapling in patients receiving ciprofloxacin as part of routine clinical care.|PROCEDURE: blood sampling in patients receiving amikacin as part of routine clinical care.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-gene Edited Anti-CD7 CAR T Cells for Relapsed/Refractory T Cell Malignances
Status: UNKNOWN
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Acute Lymphoblastic Lymphoma|T-cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: CD7 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Pharmacokinetic Study to Evaluate Different Manufacturing Batches of BAT1706 Injection
Status: NOT_YET_RECRUITING
Conditions: Healthy Men
Interventions: DRUG: BAT1706 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain Perfusion & Oxygenation in Parkinson's Disease With NOH
Status: COMPLETED
Conditions: Parkinson Disease|Neurogenic Orthostatic Hypotension
Interventions: DRUG: Droxidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nudging Handwashing: a Cluster-randomized Trial in Bangladesh
Status: COMPLETED
Conditions: Hand Disinfection
Interventions: BEHAVIORAL: Early handwashing station|BEHAVIORAL: Late handwashing station|BEHAVIORAL: Nudge|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Randomized, Placebo-controlled, Double-blind Clinical Trial of Curcuminoids in Oral Lichen Planus
Status: TERMINATED
Conditions: Oral Lichen Planus
Interventions: DRUG: Curcuminoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance-Related Disorders|Substance Use|Substance Use Disorders|Stigma, Social|Stigmatization|Attitude of Health Personnel|Treatment Adherence|Treatment Adherence and Compliance|Health Care Seeking Behavior|HIV|Mental Health Recovery|Delivery of Health Care|Global Health|South Africa|Health Personnel Attitude|Health Personnel|Community Health Workers|Substance Use Recovery
Interventions: BEHAVIORAL: Siyakhana - P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Test if TEV-53275 is Effective in Relieving Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: TEV-53275 Dose A|DRUG: TEV-53275 Dose B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain-Oscillation-Synchronized Stimulation to Enhance Motor Recovery in Early Subacute Stroke
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DEVICE: Bossdevice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: melanoma helper peptide vaccine|BIOLOGICAL: multi-epitope melanoma peptide vaccine|BIOLOGICAL: tetanus toxoid helper peptide|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FNB in ACL Recon Under SA
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Rupture|Femoral Nerve Block
Interventions: PROCEDURE: Sono-guided injection|DRUG: Ropivacaine injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-centre Study to Assess the Safety, Tolerability, and Pharmacokinetics of Capivasertib (AZD5363) in Combination With Novel Agents in Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Capivasertib|DRUG: Enzalutamide|DRUG: Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound-guided Transverse Carpal Ligament Release for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: long-axis needle release|OTHER: short-axis needle release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture/Moxibustion for Irritable Bowel Syndrome (IBS)
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Standard Acupuncture/Moxibustion (fixed protocol)|OTHER: Individualized Acupuncture/Moxibustion|OTHER: Sham/Placebo Acupuncture/Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Non-Surgical Periodontal Therapy on Glycemic Control and Bacterial Levels in a Mexican-American Population With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Periodontal Disease
Interventions: PROCEDURE: Periodontal Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Socio-legal Services for Underserved Populations Through Patient Navigation to Optimize Resources During Treatment
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Patient navigation enhanced with legal support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer.
Status: RECRUITING
Conditions: Ductal Breast Carcinoma in Situ|Invasive Breast Cancer|Early-stage Breast Cancer|Stage 0 Breast Cancer|Stage I Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer
Interventions: RADIATION: Hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Nivolumab in the Treatment of Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: DRUG: nivolumab and ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobilising Lower Limb Fluid for Hemodynamic Stability in Haemodialysis
Status: UNKNOWN
Conditions: Kidney Failure
Interventions: DEVICE: Intermittent pneumatic compression device|DEVICE: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Tiotropium HFA BAI 5 mcg|DRUG: Tiotropium 18 mcg Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mixed Meal Test in Type 1 Diabetes on Insulin Pump Therapy: Optimization of Artificial Pancreas
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Clamp-Mixed Meal|OTHER: IVGTT-Mixed Meal Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bupivacaine Versus Lidocaine on Inflammatory Regulation
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve Registry
Status: UNKNOWN
Conditions: Aortic Stenosis|Mitral Regurgitation
Interventions: DEVICE: TAVI|DEVICE: TMVR/r
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
Status: COMPLETED
Conditions: Obese|Cigarette-smoking|Schizophrenia
Interventions: DRUG: Naltrexone|DRUG: Placebo Naltrexone|DRUG: Bupropion|DRUG: Placebo Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WayToServePlus: Improving Responsible Alcohol Service Ph II
Status: RECRUITING
Conditions: Alcohol Drinking|Alcohol Intoxication|Alcohol Use, Unspecified
Interventions: BEHAVIORAL: WayToServe Plus In-service Component|BEHAVIORAL: WayToServe Training Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Effect of TAP-catheter and Epidural Catheter on Postoperative Pain After Open Gynecologic Surgery
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine bolus in transversus abdominis plane catheter|DRUG: Bupivacain-infusion in epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Status: COMPLETED
Conditions: Syncope
Interventions: DEVICE: Novel ambulatory patch (ZIO® XT Patch)|BIOLOGICAL: BNP and hs-troponin I at 0 and 3 hours post ED attendance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnosis and Definition of Local Involvement of Musculoskeletal Tumors: Assessment of Ultra-high Field MRI Exploration Contribution
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DEVICE: Magnetic Resonance Imaging (MRI) 7 Tesla|DEVICE: Magnetic Resonance Imaging (MRI) 1,5 Tesla
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pressure Pain Tolerance in Relation to Balance and Strength in Children
Status: RECRUITING
Conditions: Sickle Cell Anemia
Interventions: OTHER: Pressure pain tolerance measurement using Digital Pressure Algometer|OTHER: Balance assessment using HUMAC balance system|OTHER: Lower limb muscular strength using Lafayette hand held dynamometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intranasal Submucosal Bevacizumab for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)
Status: COMPLETED
Conditions: HHT|Morbus Osler|Epistaxis
Interventions: DRUG: Bevacizumab|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: dexamethasone|DRUG: clarithromycin|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Spinal Techniques for for Cesarean Delivery Anesthesia
Status: WITHDRAWN
Conditions: Hypotension|Headache
Interventions: DEVICE: Wiley Spinal Catheter|DEVICE: Spinal Anesthesia Group (SAG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study)
Status: COMPLETED
Conditions: Chronic Ischemic Left Ventricular Dysfunction|Myocardial Infarction
Interventions: BIOLOGICAL: Allogeneic hMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: MEBO Wound Ointment|PROCEDURE: Standard of Care (sterile saline moistened gauze)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Monitoring of Endovascular Repair of Abdominal Aortic Aneurysm (VBA)
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Abdominal Aortic Aneurysm
Interventions: DIAGNOSTIC_TEST: Noninvasive pulse wave analysis sensor, ECG-sensor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amendment (g) Unblinded Extension Phase of Somatropin in Patients With Idiopathic Short Stature
Status: COMPLETED
Conditions: Growth Disorder
Interventions: DRUG: somatropin, rDNA origin, for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib and Carboplatin in Treating Patients With HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Negative|Progesterone Receptor Positive|Recurrent Breast Carcinoma|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma
Interventions: DRUG: Carboplatin|OTHER: Fluorothymidine F-18|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Positron Emission Tomography|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Enhanced Recovery After Surgery in Orthognathic Surgery
Status: COMPLETED
Conditions: Enhanced Recovery After Surgery|Hospital Stay|Postoperative Nausea and Vomiting|Pain, Postoperative
Interventions: PROCEDURE: Traditional Approach|PROCEDURE: Enhanced Recovery After Surgery (ERAS) Approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness of Omega 3-Fatty Acids, EPA Versus DHA, for the Treatment of Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: eicosapentaenoic acid|DIETARY_SUPPLEMENT: docosahexaenoic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Quality of Life Measurement Scale in Hereditary Haemorrhagic Telangiectasia (HHT) Disease.
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia
Interventions: OTHER: Phase 1 : fill out 1 scale|OTHER: Phase 2 : fill out 1 scale and 4 questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of I-131 Tositumomab in Patients With Relapsed/Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Disease
Interventions: DRUG: I-131 Tositumomab therapeutic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascularized Composite Allotransplantation for Treatment of Abdominal Wall Defects
Status: RECRUITING
Conditions: Abdominal Wall Defect
Interventions: PROCEDURE: abdominal wall transplantation|DRUG: Immunosuppressive Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Organic Plant-rich Diet on Gut Microbiome and Vascular Function (ORGAMIC Pilot Study)
Status: COMPLETED
Conditions: Healthy Men and Women
Interventions: OTHER: Organic diet|OTHER: Non-organic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D2 (Ergocalciferol)|DRUG: Medroxyprogesterone (Provera)|DIETARY_SUPPLEMENT: Vitamin D3 (Cholecalciferol)|DIETARY_SUPPLEMENT: Elemental Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Spanish Version of CANreduce With or Without Psychological Support and Treatment as Usual, Reducing Cannabis Use.
Status: UNKNOWN
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: CANreduce|BEHAVIORAL: psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Compelled Body Weight Shift Technique for Rehabilitation of Individuals With Chronic Stroke
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: OTHER: Compelled Body Weight Shift Technique|OTHER: Compelled Body Weight Shift Technique without insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound TFP (Transversalis Fascia Plane) for Analgesia After Iliac Crest Bone Graft Harvest
Status: COMPLETED
Conditions: Patients Scheduled for Iliac Crest Bone Graft Harvest During Upper or Lower Limb Surgery
Interventions: DRUG: TFP block ropivacaine|DRUG: ropivacaine infiltration of the iliac crest bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With a Fracture
Status: RECRUITING
Conditions: Fracture of Hip|Total Hip Arthroplasty|Prosthetic-joint Infection|Fracture Acetabular
Interventions: OTHER: Antibiotic dosage practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pivotal Study Of SU011248 In The Treatment Of Patients With Cytokine-Refractory Metastatic Renal Cell Carcinoma.
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Femoral Tunnel and Clinical Outcome Using Two Anterior Cruciate Ligament Reconstruction Techniques
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: type of anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine in Cardiac Surgery: A Pilot Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Evaluate video clinic visit prior to Face-to-Face usual care visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Antidepressant Effect of Right Prefrontal Low Frequency rTMS in an Accelerated Treatment Model
Status: WITHDRAWN
Conditions: Depression
Interventions: PROCEDURE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The McKenzie System With Arthritic Knees: Do Some Knees Respond to Specific Exercise More Than General or no Exercise
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Exercise|PROCEDURE: Evidence based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine Supplementation
Status: COMPLETED
Conditions: Secondary Hypothyroidism|Hypopituitarism|Hyperlipidemias
Interventions: DRUG: Thyroxin, Triiodothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pain and Bruising of Subcutaneous Heparin Injection
Status: TERMINATED
Conditions: Pain|Bruising
Interventions: PROCEDURE: 10s injections duration|PROCEDURE: 10s injection duration and waiting 10s before withdrawing the needle|PROCEDURE: 15s injection duration and waiting 5s before withdrawing the needle|PROCEDURE: 5s injection duration and waiting 15s before withdrawing the needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study to Investigate Safety, Tolerability, PK/PD of J2H-1702 in Healthy Females
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Amg dose administration group|DRUG: Amg dose administration group- Placebo|DRUG: Bmg dose administration group|DRUG: Bmg dose administration group- Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.
Status: COMPLETED
Conditions: Healthy Volunteers (Diabetes Mellitus, Type 2)
Interventions: DRUG: NNC0519-0130|DRUG: Placebo (NNC0519-0130)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Versus Atezolizumab Plus Bevacizumab as First Line in NSCLC Patients (BEAT)
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer Patients
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Stigma on Compliance to Medication in Functional Dyspepsia
Status: UNKNOWN
Conditions: Functional Gastrointestinal Disorders|Adherence, Patient
Interventions: BEHAVIORAL: explanation when prescribing psychoactive medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endeavor to Stop Nausea/Vomiting Associated With Pregnancy (E-SNAP)
Status: TERMINATED
Conditions: Pregnancy|Severe Nausea and Vomiting|Hyperemesis Gravidarum
Interventions: DRUG: Mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of Neramexane on the Pharmacokinetics of a Combined Drospirenone/Ethinyl Estradiol Oral Contraceptive in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Neramexane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Cranial Ultrasound for Prehospital ICH Diagnosis
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Acute Ischemic Stroke
Interventions: PROCEDURE: Cranial Point of Care Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Lactoferrin in High Calorie Formula on IL-6 and IL10 in Children With Failure to Thrive and Infection
Status: COMPLETED
Conditions: Failure to Thrive|Infections
Interventions: DIETARY_SUPPLEMENT: High Calorie Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Park Study Assessing Rhinix™ Nasal Filters for Hay Fever
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DEVICE: Placebo Filter|DEVICE: Rhinix Nasal Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia HoFH
Interventions: DRUG: evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Small Dose of Naloxone,Minimize Intrathecal Morphine Side Effects
Status: COMPLETED
Conditions: Post-Op Complication
Interventions: DRUG: Morphine|DRUG: Morphine-Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2a, Open-label Study of Vactosertib in Combination With Durvalumab in Advanced NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer Metastatic
Interventions: DRUG: TEW-7197
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR
Status: RECRUITING
Conditions: Transcatheter Aortic Valve Replacement|Antithrombotic Therapy|Bioprosthetic Valve Thrombosis
Interventions: DRUG: Oral anticoagulation therapy|DRUG: Single antiplatelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Solid Neoplasm|Recurrent Adrenal Gland Pheochromocytoma|Recurrent Ectomesenchymoma|Recurrent Ependymoma|Recurrent Ewing Sarcoma|Recurrent Hepatoblastoma|Recurrent Kidney Wilms Tumor|Recurrent Langerhans Cell Histiocytosis|Recurrent Malignant Germ Cell Tumor|Recurrent Malignant Glioma|Recurrent Medulloblastoma|Recurrent Melanoma|Recurrent Neuroblastoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Osteosarcoma|Recurrent Peripheral Primitive Neuroectodermal Tumor|Recurrent Rhabdoid Tumor|Recurrent Rhabdoid Tumor of the Kidney|Recurrent Rhabdomyosarcoma|Recurrent Soft Tissue Sarcoma|Recurrent Thyroid Gland Carcinoma|Recurrent WHO Grade 2 Glioma|Refractory Adrenal Gland Pheochromocytoma|Refractory Ependymoma|Refractory Ewing Sarcoma|Refractory Hepatoblastoma|Refractory Langerhans Cell Histiocytosis|Refractory Malignant Germ Cell Tumor|Refractory Malignant Glioma|Refractory Medulloblastoma|Refractory Melanoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Refractory Peripheral Primitive Neuroectodermal Tumor|Refractory Rhabdoid Tumor|Refractory Rhabdoid Tumor of the Kidney|Refractory Rhabdomyosarcoma|Refractory Soft Tissue Sarcoma|Refractory Thyroid Gland Carcinoma|Refractory WHO Grade 2 Glioma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Radionuclide Imaging|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Euglyca Application in Children and Adolescents With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: COMBINATION_PRODUCT: Euglyca application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Durvalumab or Durvalumab Plus Chemotherapy in Kras Mutation Positive and PD-L1 High (≥ 50%) NSCLC Patients
Status: WITHDRAWN
Conditions: Lung Cancer|Non-small Cell Lung Cancer|PD-L1 Gene Mutation|KRAS Activating Mutation
Interventions: DRUG: Durvalumab|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Cardiogenic Shock|Congenital Heart Disease|Cardiomyopathies
Interventions: DEVICE: Cardiohelp device (VA-ECMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Usability and Patient Satisfaction With Digital Urinalysis in the Context of Routine Pre-natal Care.
Status: UNKNOWN
Conditions: Pregnancy
Interventions: DEVICE: Dip HBDA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Characterize Acute and Chronic Directional Aspects of Deep Brain Stimulation
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: BSC Deep Brain Stimulation System with Directional Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety and Immunogenicity of a Prime-boost Vaccine Regimen of GEO-D02 DNA and MVA/HIV62B With and Without B63521^11 gp120 and IHV01 gp120 Env Proteins in Healthy, HIV-uninfected Adult Participants
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: GEO-D02 DNA|BIOLOGICAL: MVA/HIV62B Vaccine|BIOLOGICAL: B63521^11 gp120|BIOLOGICAL: IHV01 Protein|BIOLOGICAL: Protein Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Sequential Paclitaxel Plus Cisplatin Chemotherapy and Radiotherapy as 1st Line Treatment for Esophageal Squamous Cell Cancer
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Cancer
Interventions: OTHER: Sequential chemotherapy (paclitaxel 175mg/m2 d1; cisplatin 37.5mg/m2 d1,d2) and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Biliary Radiofrequency Ablation of Malignant Distal Common Bile Duct Strictures
Status: TERMINATED
Conditions: Pancreatic Cancer|Cholangiocarcinoma
Interventions: PROCEDURE: SEMS only|PROCEDURE: EBRFA and SEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeoTIL in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: NeoTIL|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Impact of a Programme to Improve Interaction Among Professionals on the Management of Task Interruptions"
Status: UNKNOWN
Conditions: Quality of Life
Interventions: OTHER: Identify work interruptions|OTHER: Understand work interruptions|OTHER: Act to limited work interruptions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Cognitive Function in Elderly Patients After Laser Laryngeal Surgery: Des vs Prop
Status: UNKNOWN
Conditions: Cognition Disorders in Old Age
Interventions: DRUG: Propofol|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Adequacy of Giro-Couch to Support Prone Breast Boost Irradiation Using IMRT Technique With IGRT.
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: Support Device for Prone radiation therapy (Giro-Couch)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Carcinoma Non-resectable|Stage IV Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-1293 Compared With a Basal Insulin in Participants With Type 1 Diabetes (MK-1293-005)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: MK-1293|DRUG: EU-Lantus™|DRUG: Novolog™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Single Plasma Exchange and Double Filtration Plasmapheresis (DFPP) on Peripheral Lymphocyte Phenotypes in Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: COMPLETED
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Myelodysplastic Syndrome/Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Cytarabine|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Midostaurin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Photopheresis Using Theraflex ECP™ for Patients With Refractory Chronic Graft Versus Host Disease (cGVHD)
Status: UNKNOWN
Conditions: Refractory Chronic Graft Versus Host Disease (cGVHD)
Interventions: DEVICE: Photopheresis Theraflex ECP™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of Manual Therapy in Temporomandibular Joint Disorder
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: OTHER: mandibular nonspecific mobilization|OTHER: Ultrasound detuned,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Balsalazide Disodium vs. Mesalamine in Mildly to Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis
Interventions: DRUG: Balsalazide disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients
Status: COMPLETED
Conditions: Absorption|Pharmacokinetic
Interventions: DIETARY_SUPPLEMENT: Hydration Multiplier + Energy|DIETARY_SUPPLEMENT: Hydration Multiplier + Sleep|DIETARY_SUPPLEMENT: Energy Comp|OTHER: Sleep Comp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MIND Diet Intervention and Cognitive Decline
Status: COMPLETED
Conditions: Cognitive Decline|Dementia|Alzheimer Disease|Vascular Dementia
Interventions: BEHAVIORAL: MIND Diet|BEHAVIORAL: Mild Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liver Transplant European Study Into the Prevention of Fungal Infection
Status: COMPLETED
Conditions: Liver Transplantation|Mycoses
Interventions: DRUG: micafungin|DRUG: fluconazole|DRUG: liposomal amphotericin B|DRUG: caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Epilepsy|Bipolar Disorder
Interventions: DRUG: Divalproex Sodium 500 mg DR Tablets (Sandoz Inc., USA)|DRUG: Depakote 500 mg DR Tablets (Abbott Laboratories, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Fracture Resistance and Color Changes of Laminate Veneer With Gull Wing Preparation
Status: UNKNOWN
Conditions: Discolored Teeth
Interventions: PROCEDURE: modified gull wing preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spectral Correlates of Impulsivity in Patients With Traumatic Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: transcranial pulsed current stimulation|DEVICE: Sham-no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation
Status: RECRUITING
Conditions: Slow Transit Constipation|Surgery
Interventions: PROCEDURE: subtotal colectomy with cecal-rectal anastomosis|PROCEDURE: total colectomy with ileorectal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Allogeneic Umbilical Cord Derived Hematopoietic and Mesenchymal Stem Cells in Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic
Interventions: BIOLOGICAL: MNC|BIOLOGICAL: MSC|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Utility of feNO in the Differential Diagnosis of Chronic Cough
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Montelukast (High FeNO group)|DRUG: Prednisolon, Montelukast (High FeNO)|DRUG: Montelukast (Low FeNO group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Gemcitabine and Fractionated, Weekly Cisplatin For Muscle Invasive Bladder Cancer and Patients Not Candidates For High Dose Cisplatin
Status: TERMINATED
Conditions: Invasive Bladder Cancer|Bladder Cancer
Interventions: DRUG: Gemcitabine and fractionated cisplatin (combination treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Package Prototype (OPP)
Status: RECRUITING
Conditions: Opioid Use|Opioid Prescribing, Dispensing, and Patient Use
Interventions: OTHER: Opioid Package Prototype (OPP)|OTHER: Usual Care (standard amber vial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Course of Bortezomib in Anemic Patients With Refractory Cold Agglutinin Disease
Status: COMPLETED
Conditions: Refractory Cold Agglutinin Disease
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vanadis® NIPT for Non-invasive Prenatal Screening of Trisomies (T21, T18 and T13)
Status: UNKNOWN
Conditions: Trisomy 21|Trisomy 18|Trisomy 13
Interventions: OTHER: Vanadis NIPT system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p