pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of Children
Status: COMPLETED
Conditions: Preoperative Sedation
Interventions: DRUG: Dexmedetomidine hydrochloride nasal spray|DRUG: Dexmedetomidine hydrochloride nasal spray blank preparation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT for Innovating Stress-related eHealth
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Sexual Assault|Pain
Interventions: DEVICE: RISE Guide|DEVICE: Relaxation Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Scalable Psychological Intervention to Reduce Psychological Distress Among Workers of Assisted Living Facilities
Status: RECRUITING
Conditions: Depression|Anxiety|Psychological Distress
Interventions: BEHAVIORAL: Doing What Matters (DWM)|BEHAVIORAL: Problem Management Plus (PM+)|BEHAVIORAL: Psychological First Aid (PFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of L-DOPA as a Treatment to Improve Vision in Albinism
Status: COMPLETED
Conditions: Albinism
Interventions: DRUG: Levodopa|DRUG: Levodopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of Change of an Emotion-oriented Version of Cognitive-behavioral Therapy for Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Delusions|Emotions|Self-esteem|Sleep
Interventions: BEHAVIORAL: emotion-oriented Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine Transporter Blockade, Autonomic Failure (NETAF)
Status: COMPLETED
Conditions: Neurogenic Orthostatic Hypotension
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N2001-02: I-MIBG With Intensive Chemotherapy and Autologous Stem Cell Rescue for High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Filgrastim|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Melphalan|PROCEDURE: Peripheral blood stem cell infusion|RADIATION: 131I-MIBG|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1|Neurofibroma Plexiform
Interventions: DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Multiple Myeloma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: bendamustine hydrochloride|DRUG: dexamethasone|BIOLOGICAL: filgrastim|PROCEDURE: leukapheresis|OTHER: laboratory biomarker analysis|OTHER: flow cytometry|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Sarilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18-month Study of Long-term Efficacy & Safety of Safinamide as add-on Therapy in Patients With Mid-late Stage PD
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Safinamide|DRUG: Safinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colonisation Resistance Study
Status: WITHDRAWN
Conditions: Healthy Infants
Interventions: OTHER: Regular non-hydrolysed cow's milk|OTHER: Regular non-hydrolysed cow's milk|OTHER: Regular non-hydrolysed cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Evaluate Camrelizumab Combined With Famitinib as Subsequent Therapy in Patients With Advanced NSCLC
Status: TERMINATED
Conditions: Advanced NSCLC
Interventions: DRUG: camrelizumab + famitinib|DRUG: famitinib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE)
Status: COMPLETED
Conditions: Intestinal Epithelial Dysplasia|Tufting Enteropathy
Interventions: GENETIC: blood samples and skin biopsies|GENETIC: Skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetic Determinants of Warfarin Anticoagulation Effect
Status: UNKNOWN
Conditions: Venous Thrombosis|Pulmonary Embolism|Atrial Fibrillation
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: AL001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: DEVICE: Mepilex® Border Sacrum and Mepilex® Border Heel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SLOW-Slower Progress of caLcificatiOn With Vitamin K2
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Aortic Valve Calcification|Mitral Annular Calcification|Mitral Valve Calcification|Mitral Valve Stenosis
Interventions: DIETARY_SUPPLEMENT: Vitamin K2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Study of Safety and Efficacy of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-08)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Primarily the Tolerability and Safety of SAR439794 After Repeated Sublingual Daily Administration in Peanut Allergic Adult and Adolescent Patients
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Glucopyranosyl Lipid A (GLA)|DRUG: Sublingual Immuno Therapy (SLIT) Peanut Extract (PE)|DRUG: Placebo for GLA|DRUG: Placebo for SLIT PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indomethacin Plus Biological Therapy in Treating Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: lymphokine-activated killer cells|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cyclophosphamide|DRUG: indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Virosensor -Based Real-time Diagnosis of Enterovirus 71 and Influenza Virus
Status: UNKNOWN
Conditions: Enterovirus 71 and Influenza Virus
Interventions: DEVICE: virosensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Palliative Care on Quality of Life of Advanced Cancer Patients
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Gastric Cancer|Pancreatic Cancer|Biliary Tract Cancer
Interventions: OTHER: Early Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Further Therapeutic Strategies With Guselkumab in Participants With Moderate-to-Severe Plaque-Type Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Guselkumab|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ARRY-380 + Trastuzuamab for Breast w/ Brain Mets
Status: COMPLETED
Conditions: Brain Metastases From HER2 and Breast Cancer|Advanced HER2-positive Breast Cancer
Interventions: DRUG: ARRY-380 Twice Daily Dosage|DRUG: ARRY-380 Once Daily|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Metformin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants
Status: COMPLETED
Conditions: Apnea of Prematurity
Interventions: DEVICE: NCPAP as mode for apnea prevention|DEVICE: NIPPV as rescue mode for apnea prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Galantamine HBr (Reminyl) in Electroconvulsive Therapy: Impact on Mood and Cognitive Functioning
Status: COMPLETED
Conditions: Major Depression|Bipolar Depression|Schizoaffective Disorder
Interventions: DRUG: Razadyne|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized, Double Blind Comparative Study on the Use of Two Creams in Xerosis Atopic Probands
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: vitreoscilla filiformis cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: COMPARISON OF PIEZOSURGERY AND CONVENTIONAL ROTARY INSTRUMENTS IN IMPACTED THIRD MOLAR SURGERY
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: OTHER: Piezosurgery group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Classical Hodgkin Lymphoma
Interventions: DRUG: Sabestomig (AZD7789)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blastocystis and Cryptosporidium Infection in Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Blastocystis Infection|Cryptosporidium Infection|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: ELISA / PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Novel Combinations of Tolterodine/Pilocarpine on Pharmacokinetics (PK) and Pharmacodynamics (PD) of Tolterodine in Healthy Subjects
Status: COMPLETED
Conditions: Incontinence
Interventions: DRUG: Tolterodine|DRUG: Pilocarpine|DRUG: THVD-201|DRUG: THVD-201|DRUG: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis
Status: UNKNOWN
Conditions: End-Stage Kidney Disease
Interventions: DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Air QTM Intubating Airway Versus Ambu-Aura Intubating Laryngeal Mask
Status: UNKNOWN
Conditions: Airway Management|Obesity
Interventions: DEVICE: Air-Q intubating laryngeal airway|DEVICE: Ambu-Aura intubating laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer|Advanced Non Small Cell Lung Cancer
Interventions: DRUG: MRTX849|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective and Monocentric Study of the Incidence of Venous Thromboembolic Disease (VTE) in Spinal Cord Injury (SCI) Patient Between 3 and 12 Months After SCI
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: OTHER: Venous Doppler ultrasound of the lower limbs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Efficacy and Safety of Cannabis Oil for the Treatment of Subjects With Hidradenitis Suppurativa
Status: WITHDRAWN
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Cannabis oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Intubation in Prehospital Scenario
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: C-MAC laryngoscope|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Stellate Ganglion Block With Botulinum
Status: COMPLETED
Conditions: Change From Baseline House-Brackmann
Interventions: DRUG: Botox|DRUG: triamcinolonacetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIST Therapy's Effectiveness in Wound Bed Preparation and Role of Bacterial Biofilm in Chronic, Non-healing Wounds
Status: WITHDRAWN
Conditions: Chronic Nonhealing Wounds
Interventions: DEVICE: MIST Therapy|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Treatment Strategy for Adolescent Depression-Continuation
Status: COMPLETED
Conditions: Adolescent Depression
Interventions: DRUG: Fluoxetine|BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of PRJ212 to Improve the Memory of Patients With Mild Severity Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: PRJ212|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers
Status: RECRUITING
Conditions: Metastatic Malignant Female Reproductive System Neoplasm
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Volume Modulated Arc Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Informational Intervention in Increasing Lactation Practices by African American Women
Status: COMPLETED
Conditions: Healthy Subject|Pregnant
Interventions: OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Interview|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Can the Point-Of-Care Chemistry Test (POCT) Solve the Emergency Department (ED) Crowding?
Status: COMPLETED
Conditions: Crowding
Interventions: DEVICE: point-of-care chemistry test(POCT) (Piccolo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Telemonitoring and Telemedicine Service for Type 2 Diabetes Care
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: Telemonitoring group|PROCEDURE: Telemonitoring & Telemedicine|OTHER: SMBG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Intoxication|Alcohol Impairment|Drive|Driving Impaired|Driving Under the Influence|Behavior, Drinking
Interventions: BEHAVIORAL: Loss-framed text message|BEHAVIORAL: Gain-Framed text message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Using ICDAS II and KaVo DIAGNOdent Pen Detecting Tooth Pit and Fissure Level Incipent Caries Progression
Status: UNKNOWN
Conditions: Dental Caries on Pit and Fissure Surface
Interventions: OTHER: glass ionomer sealants|OTHER: resin-based sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Sacubitril/Valsartan on Quality of Life and Mortality of CKD vs Non-CKD in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure NYHA Class IV|Heart Failure NYHA Class II
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monoclonal Antibody Vaccine Therapy in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: abagovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Modulation of the Tumor Microenvironment by MK-3475 (Pembrolizumab) Using a Systems Biology Approach (PEMSYS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma Naive to Immune Therapy in Metastatic Setting
Interventions: DRUG: Pembrolizumab|DRUG: Pembrolizumab - additional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Atropine for Symptomatic Vitreous Floaters
Status: NOT_YET_RECRUITING
Conditions: Vitreous Floaters
Interventions: DRUG: 0.01% atropine ophthalmic drop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors of Middle Cerebral Artery Aneurysm.
Status: COMPLETED
Conditions: Middle Cerebral Artery Aneurysm
Interventions: DIAGNOSTIC_TEST: Computed tomography angiography (3D CTA)|DIAGNOSTIC_TEST: Transcranial color-coded sonography (TCCS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reduction of Visual and Auditory Stimuli to Reduce Pain During Venipuncture in Premature Infants.
Status: UNKNOWN
Conditions: Premature|Pain, Procedural
Interventions: PROCEDURE: Stimuli reduction|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants
Status: RECRUITING
Conditions: Premature Infant|Respiratory Distress Syndrome in Premature Infant|Neurodevelopmental Outcome
Interventions: DRUG: 30% oxygen group|DRUG: 60% oxygen group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beet Supplementation, Exercise, Inflammation
Status: COMPLETED
Conditions: Inflammatory Response|Metabolic Disturbance|Immune Suppression
Interventions: DIETARY_SUPPLEMENT: Beet|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Budesonide/Formoterol Easyhaler and Symbicort Turbohaler in Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide and formoterol 200/6 microg|DRUG: budesonide and formoterol 200/6 microg|DRUG: budesonide and formoterol 200/6 microg|DRUG: budesonide and formoterol 200/6 microg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults
Status: COMPLETED
Conditions: Memory Impairment|Alzheimer's Disease
Interventions: DRUG: Roflumilast|DRUG: Roflumilast placebo|DRUG: Donepezil|DRUG: Donepezil placebo|DRUG: Scopolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Estradiol Addback
Status: COMPLETED
Conditions: Normal Healthy Volunteers
Interventions: DRUG: Degarelix|DRUG: Testosterone|DRUG: Anastrozole|DRUG: Estrogen patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DIFFIR - Geriatric Distal Femur Fixation Versus Replacement
Status: RECRUITING
Conditions: Distal Femur Fracture
Interventions: PROCEDURE: Distal femoral replacement|PROCEDURE: Surgical Fixation (ORIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-Way Crossover Study to Compare the Safety, Tolerability and Pharmacokinetics of New Oral Cannabinoid Formulations Administered as Single Doses, With Buccal Sativex®, in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PNL-THC:CBD soft gelatin capsule|DRUG: Sativex|DRUG: CBD hard capsule dose 1|DRUG: P-PNL-THC:CBD soft gelatin capsule|DRUG: CBD hard capsule dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis Type 1
Interventions: OTHER: Neuropsychological examination and quality of life measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Use of Ventavis in Patients With Postembolic Residual Pulmonary Hypertension
Status: UNKNOWN
Conditions: Residual Pulmonary Hypertension
Interventions: DRUG: Ventavis|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project
Status: ACTIVE_NOT_RECRUITING
Conditions: PrEP Adherence Monitoring
Interventions: DRUG: tenofovir disoproxil and emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid to Reduce Infection After Gastrointestinal Surgery
Status: RECRUITING
Conditions: Infection Wound|Gastrointestinal Complication|Anesthesia|Bleeding|Healthcare Associated Infection
Interventions: DRUG: Tranexamic Acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Application on Independence and Hand Functions in Daily Life in Children With CP
Status: NOT_YET_RECRUITING
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: ArmeoSenso|OTHER: Traditional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does it Worth to Reinforce With Additional Anesthesia to Improve Postoperative Course After Orthognathic Surgery?
Status: COMPLETED
Conditions: Dentofacial Deformities
Interventions: DRUG: Second infiltration pre-extubation with ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MTL-CEBPA in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumours (TIMEPOINT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: MTL-CEBPA|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study To Investigate The Pharmacokinetics, Safety And Tolerability Of CP-601,927 In Healthy Japanese Subjects
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: CP-601,927|DRUG: CP-601,927|DRUG: CP-601,927|DRUG: Placebo|DRUG: CP-601,927|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trastuzumab Plus Paclitaxel in Treating Women With Metastatic Breast Cancer That Overexpresses HER2
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria
Status: TERMINATED
Conditions: Binocular Dysfunction|Vertical Heterophoria|Vision, Binocular|Vision Disparity
Interventions: DEVICE: Lenses containing prismatic correction|DEVICE: Lenses not containing prismatic correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) and Motor Training for Traumatic Brain Injury (TBI) Survivors
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation|DEVICE: Armeo training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Functional Imaging Combined With Metabolomics in Predicting the Efficacy of nCRT for Locally Advanced ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)|DIAGNOSTIC_TEST: 18F-Fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT)|DIAGNOSTIC_TEST: Blood and urine metabolic biomarker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Life Assessment of Cryotherapy in Esophageal or Gastroesophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DEVICE: Administration of questionaires to patients receiving an upper endoscopy with cryotherapy in addition to chemotherapy for esophageal cancer palliation.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With Filgotinib or TNFi in RA (BACH)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Filgotinib|DRUG: Anti-Tumor Necrosis Factor Alpha Drug (Product)|BEHAVIORAL: 50 patients will have a Free Choice between Filgotinib and anti TNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guidance Model of Standardized Treatment of Antidepressants in Bipolar Disorder
Status: UNKNOWN
Conditions: the Use of Antidepressants in Patients With Bipolar Depression
Interventions: DRUG: Lithium Carbonate|DRUG: lithium carbonate combined with SSRI antidepressant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults
Status: COMPLETED
Conditions: HIV Seronegativity|HIV Preventive Vaccine
Interventions: BIOLOGICAL: MVA-C + gp140/MF59|BIOLOGICAL: MVA-C + gp140/MF59|BIOLOGICAL: DNA-C2 + MVA-C|BIOLOGICAL: DNA-C2 + MVA-C + gp140/MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Short-term Effect of 2% Atorvastatin Dentifrice in Periodontal Status.
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Medicated 2% atorvastatin dentifrice|DRUG: Non-medicated dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Carcinoma, Squamous Cell
Interventions: DRUG: oral rigosertib|DRUG: cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treated With Short Daily Hemodialysis
Status: RECRUITING
Conditions: End Stage Renal Disease|ESRD
Interventions: DEVICE: NeoKidney
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Effect of Avelumab First-Line Maintenance in Canadian People With Advanced Bladder Cancer
Status: TERMINATED
Conditions: Urinary Bladder Neoplasms|Bladder Cancer|Bladder Tumors|Urothelial Carcinoma
Interventions: DRUG: Avelumab first-line maintenance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AVATR - Arteriovenous Access Thrombosis Removal With CAPERE Thrombectomy System
Status: TERMINATED
Conditions: Arteriovenous Graft Thrombosis
Interventions: DEVICE: CAPERE Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Genistein and Interleukin-2 in Treating Patients With Metastatic Melanoma or Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: High-dose interleukin-2|DIETARY_SUPPLEMENT: genistein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF RADIOFREQUENCY ON POSTMENOPAUSAL ADIPOSE TISSUE
Status: NOT_YET_RECRUITING
Conditions: Show Positive Effect of Radiofrequancy on Postmenopausal Adipose Tissue
Interventions: DEVICE: radiofrequancy|OTHER: aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Urodynamic Effects After Vaginal Tailored Mesh Surgery for Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Anterior vaginal tailored mesh surgery|PROCEDURE: Posterior vaginal tailored mesh surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Prebiotic Food-enriched Diet (PreFED) in Combination With Ipilimumab/Nivolumab Combination Immune Checkpoint Blockade (ICB) in ICB-refractory Melanoma Patients
Status: RECRUITING
Conditions: ICB-refractory Melanoma
Interventions: OTHER: Prebiotic Food-Enriched Diet|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Validation of the Withings ECG Monitor for the Detection of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Validation of the Withings bodyscan scale WBS08
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Ginger powder|DRUG: Ibuprofen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus, Type 1
Interventions: DRUG: Dasiglucagon|DRUG: GlucaGen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DEB-TACE Versus DEB-TACE Sequential HAIC for Unresectable BCLC Stage C HCC; A Randomized Controlled Trial
Status: RECRUITING
Conditions: HCC
Interventions: PROCEDURE: DEB-TACE and HAIC|PROCEDURE: DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does ICG Fluorescence Cholangiography Identify Critical View of Safety Earlier in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: DIAGNOSTIC_TEST: Fluorescence Cholangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Continuous Positive Airway Pressure After Abdominal Surgery
Status: UNKNOWN
Conditions: Abdominal Surgery|Continuous Positive Airway Pressure|Lung Function
Interventions: DEVICE: Auto-CPAP|DEVICE: CPAP since before
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oregovomab Plus Chemotherapy in Neo-adjuvant Setting in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Neoplasm Epithelial|Ovarian Cancer|Fallopian Tube Neoplasms|Peritoneal Carcinoma|Ovarian Serous Adenocarcinoma
Interventions: BIOLOGICAL: Oregovomab|DRUG: Paclitaxel|DRUG: Carboplatin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proteolytic Enzyme Fortified Protein Supplement in Chronic Pancreatitis.
Status: NOT_YET_RECRUITING
Conditions: Chronic Pancreatitis|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Proteolytic enzyme fortified protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Phase II Dose Escalation Study Using IMRT for High Risk N0 M0 Prostate Cancer. ICORG 08-17
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|RADIATION: image-guided radiation therapy|RADIATION: intensity-modulated radiation therapy|RADIATION: radiation therapy treatment planning/simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction Scales
Status: COMPLETED
Conditions: All Orthopedic Disorders|New or Follow-up Patients
Interventions: OTHER: 5 anchors and numbers|OTHER: 5 anchors and no numbers|OTHER: Visual analog scale with 3 anchors and numbers|OTHER: Visual analog scale with 3 anchors and no numbers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of the Buprenorphine Transdermal Delivery System in Subjects With Mod-to-Sev Pain Following Orthopedic Surgery.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Buprenorphine transdermal delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Time-Restricted Fasting on the Postprandial Glycemic Responses
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Consumption of lunch and dinner, with no breakfast|BEHAVIORAL: Consumption of breakfast and lunch, with no dinner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Follow Up Study to Evaluate a Non-Surgical Device for Adult Male Circumcision for Screen Failure Subjects
Status: COMPLETED
Conditions: Male Circumcision|HIV Prevention|Screen Failure Subjects|Narrow Foreskin
Interventions: DEVICE: PrePex™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Rucaparib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mircera in Anemic Patients With Non-Small Cell Lung Cancer Receiving First Line Chemotherapy.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Darbepoetin alfa|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOMe-based HEart Failure Self-Management Programme Study (The HOM-HEMP Study)
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: HOM-HEMP|BEHAVIORAL: HOM-HEMP with smartphone app|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Combigan Two Times Daily (BID)|DRUG: Simbrinza Three Times Daily (TID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heat Therapy to Reduce Pain and Improve Walking Tolerance
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Control/Sham Treatment|DEVICE: Heat Therapy (HT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency Evaluation of Photodynamic Therapy With Photofrin® on Unresectable Type III or IV Cholangiocarcinomas
Status: TERMINATED
Conditions: Cholangiocarcinoma
Interventions: PROCEDURE: photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation and Generalized Application of "Qing-Hua-Bu" Three Dynamic Sequential Therapy of Diabetic Ulcer
Status: UNKNOWN
Conditions: Diabetic Foot|Ulcer, Skin
Interventions: DRUG: External Chinese medicine|DRUG: External Western medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
Status: COMPLETED
Conditions: Craniotomy|Seizures|Dexmedetomidine|Propofol|Remifentanil|Cerebral Tumor|Neurophysiology
Interventions: DRUG: Propofol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Life and Self-care in Patients With Diabetic Foot Ulcers Treated With Low-level Laser Therapy
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetic Foot
Interventions: DEVICE: LG1 (LLLT group 1)|DEVICE: LG2 (LLLT group 2)|DEVICE: LG3 (LLLT group 3)|DEVICE: CG (control group)|PROCEDURE: Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Phase Clinical Trial to Test the Feasibility of an ACT-based Physical Activity Promotion Program for Adults With Depressive Symptoms
Status: RECRUITING
Conditions: Physical Inactivity
Interventions: BEHAVIORAL: ACTivity|BEHAVIORAL: Relaxercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Suture Techniques on Early Healing of Peri-implant Soft Tissue
Status: NOT_YET_RECRUITING
Conditions: Dental Implants|Wound Healing|Sutures
Interventions: PROCEDURE: different suture types
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking Pattern Characteristics in Normal Pressure Hydrocephalus
Status: COMPLETED
Conditions: Idiopathic Normal Pressure Hydrocephalus (INPH)
Interventions: DEVICE: Characterization of walking pattern characteristics in an ambulatory setting using wearable IMUs (ZurichMOVE sensors)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC