pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Aerobic Exercise and Tai-chi Interventions for Improving Survival in Lung Cancer Patients
Status: COMPLETED
Conditions: Lung Cancer Patients
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Tai-Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Web-based Intervention on Parental Psychological Flexibility and Emotion Regulation
Status: UNKNOWN
Conditions: Parents
Interventions: BEHAVIORAL: Web parenting intervention|BEHAVIORAL: Group parenting intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness and Safety of Immunosuppressive and Biological Therapy of Atopic Dermatitis in Childhood
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Methotrexate therapy|DRUG: Mycophenolate mofetil therapy|DRUG: Cyclosporine therapy|DRUG: Dupilumab therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Live Attenuated Influenza Vaccine, CodaVax, Delivered Via Intranasal Spray
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CodaVax-H1N1 influenza vaccine|BIOLOGICAL: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Plasma for Early Treatment in Non-hospitalised Mild or Moderate COVID-19 Patients
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|Safety and Efficacy
Interventions: BIOLOGICAL: Convalescent anti-SARS-CoV-2 MBT plasma|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myopia Control With Novel Eye Drops
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: BHVI1 eye drops|DRUG: BHVI2 eye drops|DRUG: BHVI3 eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin And Uterotonic Agent Use For Cesarean Delivery
Status: COMPLETED
Conditions: Uterine Atony|Hypotension
Interventions: DRUG: Oxytocin Infusion|DRUG: Oxytocin Bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The NEXERCISE-trial: Reshaping Exercise Programs for Patients With Non-specific Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Blended treatment program|OTHER: Specific strength exercise program|OTHER: General aerobic exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fat Emulsions on PNALD and Oxidative Stress in Premature Infants
Status: UNKNOWN
Conditions: Preterm Infant
Interventions: DRUG: SMOFlipid|DRUG: Lipofundin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Guided Bone Regeneration Using Bovine-derived Xenograft in Combination With or Without Injectable Platelet-rich Fibrin
Status: COMPLETED
Conditions: Bone Resorption
Interventions: PROCEDURE: bovine-derived xenograft with i-PRF|PROCEDURE: bovine-derived xenograft alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Coffee Consumption on Pain and Intestinal Motility After Caesarean Section:
Status: NOT_YET_RECRUITING
Conditions: Operation|Cesarean Section
Interventions: DIETARY_SUPPLEMENT: coffee consumption|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Timing of Intrauterine Insemination (IUI) 24 or 48 Hours After Spontaneous Luteinizing Hormone (LH) Peak
Status: COMPLETED
Conditions: Pregnancy
Interventions: PROCEDURE: intra-uterine insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Haematopoietic Cell Transplantation for Patients With Refractory "Triple Negative" Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: Radiotherapy|BIOLOGICAL: Anti-Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Bioavailability Study of Lovastatin Tablets and Mevacor Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lovastatin 40 mg Tablets|DRUG: Lovastatin (Mevacor®) 40 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Anal Fissure|Hemorrhoids
Interventions: PROCEDURE: treatment of anal diseases in inflammatory bowel patients|DEVICE: Laser|PROCEDURE: traditional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery
Status: COMPLETED
Conditions: Acute Pain|Post Operative Pain|Anorectal Disorder|Analgesia
Interventions: DRUG: Intrathecal Hydromorphone Mono Injection|DRUG: Intrathecal Placebo Mono Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for Migraine - Dose Comparison
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Dexamethasone 4mg|DRUG: Dexamethasone 16mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VA-008 ACAM2000® Vaccination of Plasma Donors for the Production of VIGIV
Status: COMPLETED
Conditions: Smallpox Vaccine Adverse Reaction
Interventions: BIOLOGICAL: Vaccination with ACAM2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The All-comers Sirolimus-coated Balloon European Registry
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention|Angioplasty, Balloon, Coronary|Coronary Angioplasty, Transluminal Balloon|Arteriosclerosis, Coronary
Interventions: DEVICE: Sirolimus Coated Balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
Status: RECRUITING
Conditions: AVB - Atrioventricular Block|Fetal AVB
Interventions: DRUG: Dexamethasone|DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder
Status: COMPLETED
Conditions: Body Dysmorphic Disorder|Somatoform Disorders
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CUDC-907 Treatment in People With Metastatic and Locally Advanced Thyroid Cancer
Status: TERMINATED
Conditions: Thyroid Neoplasms|Poorly Differentiated and Undifferentiated Thyroid Cancer|Differentiated Thyroid Cancer
Interventions: DRUG: CUDC-907
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies
Status: RECRUITING
Conditions: High Risk Myeloid Malignancies|Cord Blood Transplant
Interventions: BIOLOGICAL: ECT-001-CB (UM171-Expanded Cord Blood Transplant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Daratumumab in Combination With Atezolizumab Compared With Atezolizumab Alone in Participants With Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid (Udca) as a Local Drug Delivery Agent in the Treatment of Intra-bony Defects
Status: UNKNOWN
Conditions: Bone Regeneration
Interventions: DRUG: Ursodeoxycholic acid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Arthroscopic Cartilage Regeneration Facilitating Procedure for Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis of Knees
Interventions: PROCEDURE: ACRFP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma|Bladder Cancer
Interventions: DRUG: Nivolumab in combination with Urelumab|DRUG: Nivolumab monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel 75 mg|DRUG: Prasugrel 5 mg|DRUG: Ticagrelor 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Acute Decompensated Heart Failure|Cardiorenal Syndrome|Heart Failure, Congestive|Heart Failure With Preserved Ejection Fraction|Heart Failure With Reduced Ejection Fraction|Diuretic Resistance
Interventions: DEVICE: ModulHeart Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib Plus Trastuzumab After First-line TH (P) Treatment With HER-2 Positive Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Breast Cancer
Interventions: DRUG: pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thorough QT Assessment of Cedazuridine in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cedazuridine|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Myocardial perfusion imaging using Rb-82 PET or Tc-99m or Tl SPECT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of TENS and Mindfulness Meditation in Persons With HIV-related Neuropathy
Status: RECRUITING
Conditions: HIV Infections
Interventions: DEVICE: Transcutaneous Nerve Stimulation (TENS)|BEHAVIORAL: Mindfulness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-viral Effect of PC786 on RSV Infection on HSCT Recipients
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: PC786|DRUG: Placebo|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention With Moderately High-protein, Low-glycemic Load Products in Type-2 Diabetes Patients
Status: COMPLETED
Conditions: Type-2 Diabetes|Overweight
Interventions: OTHER: Chronologically scheduled snacking with 40-30-30 products
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: REalWorld Insights on the INitiation and Treatment Duration of ticagrEloR & Other Oral Antiplatelets (OAP) in Patients With Acute Coronary Syndrome (ACS) in Be/Lux.
Status: COMPLETED
Conditions: Treatment of Acute Coronary Syndrome (ACS).
Interventions: DRUG: ACS patients treated with OAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Treating Participants With Leukoplakia
Status: RECRUITING
Conditions: Erythroleukoplakia|Leukoplakia|Verrucous Oral Leukoplakia
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcostal TAP Block With Liposomal Bupivacaine Versus Bupivacaine in Donor Nephrectomy Patients: A Prospective Study
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: liposomal bupivacaine|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Lamivudine and Entecavir Treatment in Spontaneous Severe Acute Exacerbation
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Lamivudine|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Cytal® Burn Matrix in the Management of Partial-Thickness Burns to the Hand
Status: WITHDRAWN
Conditions: Partial Thickness Burn of Hand
Interventions: DEVICE: Cytal® Burn Matrix|DEVICE: EZ-Derm® Porcine Xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Patients Treated by Preloaded Fenestrated Stent-graft Designs for Complex Endovascular Aortic Procedures
Status: COMPLETED
Conditions: Renal Aneurysm|Aneurysm Thoracic|Aneurysm Abdominal
Interventions: PROCEDURE: Complex Endovascular Aortic Procedures treated by Preloaded Fenestrated Stent-graft Designs for
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Effectiveness of Whatsapp-Based Physical Activity Incentive Program in Morbidly Obese Individuals
Status: COMPLETED
Conditions: Physical Inactivity|Obesity, Morbid
Interventions: BEHAVIORAL: Physical Activity Incentive Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Upper Trapezius Myofascial Trigger Point in Overhead Athletes After Upper Trapezius Muscle Fatigue
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain|Fatigue
Interventions: BEHAVIORAL: Upper trapezius muscle fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy for Palliative Head and Neck Cancer Treatment (PULS-Pal)
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Carcinoma|Localized Head and Neck Carcinoma|Metastatic Head and Neck Carcinoma|Recurrent Head and Neck Carcinoma
Interventions: PROCEDURE: Personalized ultrafractionated stereotactic adaptive radiotherapy|RADIATION: Volume Modulated Arc Therapy|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Best Practice|BEHAVIORAL: University of Washington Quality of Life Scale, Version 4|BEHAVIORAL: Functional Assessment of Cancer Therapy-Head & Neck
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors
Status: RECRUITING
Conditions: Melanoma
Interventions: OTHER: MySmartSkin enhancement|OTHER: Educational webpage on Skin Self-Examination|OTHER: Assess implementation outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Does the Common Practice of Adding Diluted Epinephrine in Tranverse Abdominal Plan Block to Ropivacaine Significantly Decrease the Peak Systemic Resorption of Ropivacaine?
Status: ACTIVE_NOT_RECRUITING
Conditions: Bowel Disease
Interventions: OTHER: pharmacokinetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Study Generic Calcipotriene and Betamethasone Dipropionate Topical Suspension, 0.005%/0.064%, in the Treatment of Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: Calcipotriene/Betamethasone Dipropionate|DRUG: Taclonex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Incidence of Hemolysis, Safety, and Efficacy of Tafenoquine (SB-252263, WR238605) Versus Primaquine in Subjects With Plasmodium Vivax Malaria
Status: COMPLETED
Conditions: Malaria, Vivax
Interventions: DRUG: Tafenoquine|DRUG: Tafenoquine Placebo|DRUG: Chloroquine|DRUG: Primaquine|DRUG: Primaquine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrative Medicine in Lymphoma Survivors
Status: RECRUITING
Conditions: Lymphoma
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Mind-body therapy|PROCEDURE: Touch therapy|PROCEDURE: Movement therapy|DIETARY_SUPPLEMENT: Herbal supplements|BEHAVIORAL: Emotional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diabetes and Smoking Cessation: a Gender-Oriented Study
Status: TERMINATED
Conditions: Smoking Cessation|Diabetes Type 2
Interventions: OTHER: Behavioral smoking cessation intervention|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medication Development for Opioid and Alcohol Abuse
Status: COMPLETED
Conditions: Opioid-use Disorder|Alcohol Use Disorder
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Egg Yolk Antibody in Adjuvant Treatment of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline, Bismuth|DRUG: IIaprazole, Amoxicillin/Clarithromycin/Furazolidone, Doxycycline, Bismuth|DRUG: Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline|DRUG: IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline, Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Training Fecal Incontinence in Children
Status: COMPLETED
Conditions: Fecal Incontinence in Children
Interventions: PROCEDURE: Traditional Treatment|DEVICE: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Lung Impedance-Guided Preventive Therapy in Patients With Chronic Heart Failure (CHF)
Status: UNKNOWN
Conditions: Chronic Congestive Heart Failure
Interventions: OTHER: Lung impedence-guided treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens
Status: RECRUITING
Conditions: Substance Use Disorders|PTSD
Interventions: BEHAVIORAL: RRFT (Risk Reduction through Family Therapy)|BEHAVIORAL: ENCOMPASS (Integrated Treatment for Adolescents and Young Adults)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LBBAP Data Collection Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Bradycardia|Sinus Node Dysfunction|Heart Block|Syncope|Cardiomyopathies|Heart Failure
Interventions: DEVICE: Implantation of the Tendril 2088 lead in the LBBA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atorvastatin in Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study
Status: UNKNOWN
Conditions: Acute Heart Failure|Acute Kidney Injury
Interventions: DRUG: Spironolactone or hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Colistin Versus Intravenous Colistin Plus Nebulized Colistin in VAP Due MDR Acinetobacter Baumannii
Status: UNKNOWN
Conditions: Cross Infection|Pneumonia, Bacterial
Interventions: DRUG: Colistin|DRUG: Colistin and saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone
Status: UNKNOWN
Conditions: Solitary Osseous Plasmacytoma
Interventions: DRUG: ixazomib|DRUG: lenalidomide|DRUG: dexamethasone|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (CF-EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Endoscopically Guided Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Effects on Cardiovascular System and Exercise Responses
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound- Guided Continuous Serratus Anterior Plane Block Versus Ultrasound- Guided Continuous Thoracic Paravertebral Block in Multiple Traumatic Rib Fractures.
Status: COMPLETED
Conditions: Serratus Anterior Plane Block|Thoracic Paravertebral Block|Ultrasound|Multiple Traumatic Rib Fractures|Analgesia
Interventions: PROCEDURE: Thoracic paravertebral block|PROCEDURE: Serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Assess Safety of AZD6738 Alone and in Combination With Radiotherapy in Patients With Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumour Refractory to Conventional Treatment
Interventions: DRUG: AZD6738|RADIATION: Palliative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRESSA™ (Gefitinib) With Cisplatin Plus Radiotherapy for the Treatment of Previously Untreated Unresected Late Stage III/IV Non-Metastatic Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Neoplasms, Squamous Cell
Interventions: DRUG: gefitinib (Iressa)|DRUG: cisplatin|RADIATION: radiotherapy|DRUG: Gefitinib (Iressa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: Bupropion|DRUG: Nicotine patches|OTHER: Placebo varenicline|OTHER: Placebo bupropion|OTHER: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study Comparing Carcinological and Functional Results of Surgery
Status: UNKNOWN
Conditions: Cancer of the PROSTATE
Interventions: PROCEDURE: Radical retropubic prostatectomy|PROCEDURE: Radical laparoscopy prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Stenting of TAXUS Liberté™-SR Stent for the Treatment of Patients With de Novo Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Liberté™-SR|DEVICE: TAXUS Liberté™-SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vardenafil in Greenlight(TM) Laser Surgery of Benign Prostate Hypertrophy
Status: COMPLETED
Conditions: Prostatic Hypertrophy, Benign
Interventions: DRUG: Vardenafil (Levitra, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Everolimus|DRUG: Everolimus|DRUG: Everolimus|DRUG: Exemestane|DRUG: BI 836845|DRUG: BI 836845|DRUG: Exemestane|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of a 24-Valent Pneumococcal Conjugate Vaccine (VAX-24) in Healthy Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Vaccines
Interventions: BIOLOGICAL: 0.5 ml dose of 1.1 mcg VAX-24|BIOLOGICAL: 0.5 ml dose of PCV20|BIOLOGICAL: 0.5 ml dose of 2.2 mcg VAX-24|BIOLOGICAL: 0.5 ml dose of 2.2/4.4 mcg VAX-24
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pelvic Neuromuscular Facilitation and Swiss Ball Exercises on Trunk Control in Children With Diaplegic CP
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Proprioceptive Neuromuscular Facilitation|OTHER: Swiss Ball Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
Status: COMPLETED
Conditions: Irregular; Contour of Cornea|Keratoconus|Pellucid Marginal Corneal Degeneration|Injury of Cornea|Irregular Astigmatism
Interventions: DEVICE: Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™)|DEVICE: Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of the Shockwave Lithoplasty® System for the Treatment of Peripheral Vascular Stenosis
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Shockwave Lithoplasty® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasal Polyps
Interventions: BIOLOGICAL: Depemokimab (GSK3511294)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Stepped Care for Unhealthy Alcohol Use in HIV
Status: COMPLETED
Conditions: Liver Diseases, Alcoholic|Alcoholism|HIV|Hepatitis C
Interventions: OTHER: Integrated Stepped Care (ISC)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Therapeutic Fecal Transplant on the Gut Microbiome in Children With Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal Microbial Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation for Smoking Cessation in PTSD
Status: COMPLETED
Conditions: Tobacco Dependence|PTSD
Interventions: BEHAVIORAL: Behavioral Activation Therapy|BEHAVIORAL: Health and Smoking Education|BEHAVIORAL: Standard Smoking Cessation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Multi-dose Chloroquine
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Chloroquine-base 50 mg|DRUG: Chloroquine-base 70 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Oral Mitoquinone (MitoQ) Supplementation for Improving Physiological in Middle-aged and Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: MitoQ|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)
Status: UNKNOWN
Conditions: Ataxia Telangiectasia|Growth Failure
Interventions: DRUG: Somatropin, Clonidine, L-Arginin-Hydrochloride, Estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Demonstrate the Superiority of IMP (1% OPA-15406 Ointment) to the Vehicle in Adult Patients With AD
Status: RECRUITING
Conditions: Atopic Dermatitis (AD)
Interventions: DRUG: 1% OPA-15406 Ointment|OTHER: 0% OPA-15406 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: (CB-01-02/04) Extension Study of Budesonide Multi-Matrix System (MMX) 6 mg in Maintenance Of Remission In Patients With Ulcerative Colitis.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Budesonide MMX 6 mg Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Health Electrically Evoked Recording (PEER) 2 Study
Status: RECRUITING
Conditions: Overactive Bladder|Fecal Incontinence|Urinary Retention
Interventions: DEVICE: Sacral Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Exenatide For Reducing the Reinforcing Effects of Cocaine
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes
Status: COMPLETED
Conditions: Meniere Disease
Interventions: DRUG: Venlafaxine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypothermic Oxygenated Perfusion for Extended Criteria Donors in Liver Transplantation (HOPExt)
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DEVICE: End-ischemic Hypothermic Oxygenated Machine Perfusion (HOPE)|DEVICE: classic static cold storage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail Inmates
Status: UNKNOWN
Conditions: Impulsive Behavior|Substance Abuse|HIV Risk Behavior|Anxiety|Depression|Criminogenic Thinking
Interventions: BEHAVIORAL: REVAMP|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROspective Study to OPTimize thE HEALTH of Patients With TIAs (Transient Ischemic Attacks) and Stroke Admitted to the Hamad General Hospital
Status: UNKNOWN
Conditions: Stroke|Transient Ischemic Attack (TIA)
Interventions: OTHER: Aggressive Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contralateral Leg Neuro-dynamic and Spine Mobilization With Leg Movement in Patients With Sciatica
Status: RECRUITING
Conditions: Sciatic Radiculopathy
Interventions: OTHER: CLNDT+ Conventional PT in Diabetic Population):|OTHER: CLNDT+ Conventional PT in non Diabetic Population):|OTHER: SMWLM+ Conventional PT in Diabetic Population)|OTHER: SMWLM+ Conventional PT in non Diabetic Population)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrus® Microstent New Enrollment Post-Approval Study
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: Hydrus Microstent|PROCEDURE: Cataract surgery|DEVICE: Monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Modulation of Oral Microbiota
Status: COMPLETED
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Probiotics-O (Burgerstein)|OTHER: Placebo [inactivated Probiotics-O (Burgerstein)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Dyadic Pain Management Program for Community-dwelling Older Adults With Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain|Elderly|Informal Caregivers|Dyadic Intervention
Interventions: BEHAVIORAL: Dyadic pain management program|OTHER: Usual care and pain management pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 5-Year Safety Study of Pimecrolimus Cream 1% in Infants 3 - 12 Months of Age With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Topical corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Concurrent Chemoradiotherapy as First-line Treatment for Stage IIIC2 Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: tislelizumab|OTHER: concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Treatment of Neonatal Seizures: Safety and Efficacy Phase II Study
Status: COMPLETED
Conditions: Neonatal Seizures
Interventions: DRUG: Intravenous Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Android Application as a Pharmaceutical Education Tool in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Android Application|BEHAVIORAL: Pharmacy education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: TQT2 Study to Evaluate the Effect of MD1003 on Cardiac Repolarization in Healthy Adult Subjects
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: MD1003|DRUG: Moxifloxacin 400mg|DRUG: Placebo for MD1003|DRUG: Placebo for moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Changes in Metabolic Rate and Perceptual Indicators After Acute Ingestion of Paraxanthine
Status: COMPLETED
Conditions: Metabolic Syndrome|Caffeine
Interventions: OTHER: Venous Blood Collection|OTHER: Resting Metabolic Rate Determination|OTHER: Mood State|OTHER: Visual Analog Scales
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: QUILT-3.091 NANT Chordoma Vaccine vs Radiation in Subjects With Unresectable Chordoma.
Status: WITHDRAWN
Conditions: Chordoma|Unresectable Malignant Neoplasm
Interventions: BIOLOGICAL: Aldoxorubicin Hydrochloride|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK|DRUG: Avelumab|DRUG: Cetuximab|DRUG: Cyclophosphamide|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)
Status: RECRUITING
Conditions: Mucopolysaccharidosis II
Interventions: DRUG: JR-141|DRUG: Idursulfase|DRUG: JR-141 or Idursulfase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Versus Lower Extremity Accessory Access Sites During Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Transcatheter Aortic Valve Implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short- and Long Term Antibacterial Effects of a Single Rinse With Different Mouthwashes: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Gingival Diseases|Caries
Interventions: DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Docetaxel/Cisplatin Induction Therapy Followed by Concurrent Chemoradiotherapy or Concurrent Chemoradiotherapy Followed by Consolidation Docetaxel/Cisplatin in NSCLC Patients
Status: TERMINATED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: docetaxel and cisplatin|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Status: RECRUITING
Conditions: Pulmonary Hypertension|Heart Failure With Reduced Ejection Fraction|Hypertension|Vascular Diseases|Cardiovascular Diseases|Heart Failure|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mid Range Ejection Fraction
Interventions: PROCEDURE: Pulmonary arterial denervation|DRUG: Guideline-directed medical therapy (GDMT) for heart failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Possible Protective Effect of Rosuvastatin in Chemotherapy-induced Cardiotoxicity in HER2 Positive Breast Cancer Patients
Status: COMPLETED
Conditions: Chemotherapy-induced Cardiotoxicity|Breast Cancer
Interventions: DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
Status: COMPLETED
Conditions: Vestibular Schwannoma|Neurofibromatosis Type 2
Interventions: DRUG: Endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Interventions for Bipolar Disorder (MoodSwings 2)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Moderated discussion board|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Interactive Psychosocial Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gait Training With Executive Functions Tasks in Subjects With Parkinson´s Disease: A Randomised Controlled Trial
Status: UNKNOWN
Conditions: Parkinson´s Disease
Interventions: BEHAVIORAL: Gait training executive functions tasks|BEHAVIORAL: Gait training alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VisuMax Femtosecond Laser Small Incision Lenticule Extraction for the Correction of High Myopia
Status: COMPLETED
Conditions: Myopia|Refractive Errors
Interventions: PROCEDURE: Small incision lenticule extraction|DRUG: Tobramycin and dexamethasone|DRUG: Ofloxacin|DRUG: Proxymetacaine 0.5%|DRUG: Oxybuprocaine 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Quality of Life Outcomes After Open or Robotic-Assisted Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer|Quality of Life
Interventions: BEHAVIORAL: Quality of Life Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Access to Breast Cancer Screening and Treatment in Nigeria: The Triple Mobile Assessment and Patient Navigation Model
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: iBreast device|OTHER: Clinical Breast Examination|DIAGNOSTIC_TEST: Breast ultrasound|DIAGNOSTIC_TEST: Mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects
Status: COMPLETED
Conditions: Cholestasis
Interventions: DRUG: GSK2330672 (linerixibat)|DRUG: Obeticholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Perampanel Tablets 12 mg
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Perampanel 12 MG|DRUG: Fycompa 12 mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bandage Contact Lenses for Corneal Abrasions
Status: UNKNOWN
Conditions: Corneal Abrasion|Eye Trauma
Interventions: DEVICE: Bandage contact lens|DRUG: Eyedrop|DRUG: Hydrocodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3
Status: COMPLETED
Conditions: Spinal Muscular Atrophy Type 3
Interventions: DRUG: Pyridostigmine Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT