pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Smell Training and Trigeminal Nerve Stimulation for COVID-related Smell Loss
Status: RECRUITING
Conditions: Smell Dysfunction|Olfactory Disorder|Long COVID
Interventions: DEVICE: Trigeminal Nerve Stimulation (TNS)|OTHER: Active Smell Training (ST)|OTHER: Placebo Smell Training (PBO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas
Status: TERMINATED
Conditions: Metastatic Leiomyosarcoma|Metastatic Synovial Sarcoma|Metastatic Undifferentiated Pleomorphic Sarcoma|Advanced Myxoid Liposarcoma|Advanced Soft Tissue Sarcoma|Metastatic Myxoid Liposarcoma|Metastatic Round Cell Liposarcoma|Metastatic Soft Tissue Sarcoma|Refractory Leiomyosarcoma|Refractory Myxoid Liposarcoma|Refractory Round Cell Liposarcoma|Refractory Soft Tissue Sarcoma|Refractory Synovial Sarcoma|Refractory Undifferentiated Pleomorphic Sarcoma|Advanced Leiomyosarcoma|Advanced Synovial Sarcoma|Advanced Undifferentiated Pleomorphic Sarcoma|Metastatic Chondrosarcoma
Interventions: DRUG: Itacitinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of CT-FFR Compared to CCTA or CCTA and Stress MPI in Low to Intermediate Risk ED Patients With Toshiba CT-FFR
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Artery Disease|Chest Pain|Acute Coronary Syndrome|Acute Myocardial Infarction
Interventions: DEVICE: Toshiba CT-FFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PD1-CD19-CART in Patients With r/r B-cell Lymphoma
Status: COMPLETED
Conditions: B-cell Lymphoma
Interventions: BIOLOGICAL: PD1 specific integrated anti-CD19 Chimeric Antigen Receptor T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study
Status: RECRUITING
Conditions: Peripheral Neuropathy
Interventions: DEVICE: Immediate St (Scrambler Therapy)|DEVICE: Waitlist ST (Scrambler Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effects of Different Therapy Regimens on Menopausal Sleep Disorders
Status: NOT_YET_RECRUITING
Conditions: Menopause|Sleep Disorder
Interventions: DRUG: Tibolone|DRUG: Xiangshao granules|DRUG: Tibolone plus Xiangshao granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccines Safety Tracking (CoVaST)
Status: RECRUITING
Conditions: Adverse Reaction to Vaccine|COVID19 Vaccine
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: mRNA-1273|BIOLOGICAL: AZD1222|BIOLOGICAL: CoronaVac|BIOLOGICAL: Sinopharm|BIOLOGICAL: Gam-COVID-Vac|BIOLOGICAL: JNJ-78436735|BIOLOGICAL: CVnCoV|BIOLOGICAL: NVX-CoV2373|BIOLOGICAL: BBV152
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A 5-treatment, Study in Healthy Volunteers to Assess The Safety, Tolerability, and Pharmacokinetics of Four Controlled Release (CR) Pregabalin Tablet Formulations and the Immediate Release (IR) Formulation Administered Fasted
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sequence 1 - Treatment A: Controlled Release Pregabalin|DRUG: Sequence 1 - Treatment B: Controlled Release Pregabalin|DRUG: Sequence 1 - Treatment C:Controlled Release Pregabalin|DRUG: Sequence 1 - Treatment D: Controlled Release Pregabalin|DRUG: Sequence 1 - Treatment E: Immediate Release Pregabalin|DRUG: Sequence 2 - Treatment B: Controlled Release Pregabalin|DRUG: Sequence 2 - Treatment D: Controlled Release Pregabalin|DRUG: Sequence 2 - Treatment A: Controlled Release Pregabalin|DRUG: Sequence 2 - Treatment C: Controlled Release Pregabalin|DRUG: Sequence 2 - Treatment E: Immediate Release Pregabalin|DRUG: Sequence 3 - Treatment C: Controlled Release Pregabalin|DRUG: Sequence 3 - Treatment A: Controlled Release Pregabalin|DRUG: Sequence 3 - Treatment D: Controlled Release Pregabalin|DRUG: Sequence 3 - Treatment B: Controlled Release Pregabalin|DRUG: Sequence 3 - Treatment E: Immediate Release Pregabalin|DRUG: Sequence 4 - Treatment D: Controlled Release Pregabalin|DRUG: Sequence 4 - Treatment C: Controlled Release Pregabalin|DRUG: Sequence 4 - Treatment B: Controlled Release Pregabalin|DRUG: Sequence 4 - Treatment A: Controlled Release Pregabalin|DRUG: Sequence 4 - Treatment E: Immediate Release Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of LY01011 and Xgeva® in Patients With Bone Metastases From Solid Tumors
Status: UNKNOWN
Conditions: Bone Metastases From Solid Tumors
Interventions: DRUG: LY01011|DRUG: Xgeva®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E-Selectin Nasal Instillation to Prevent Secondary Stroke
Status: WITHDRAWN
Conditions: Ischemic Attack, Transient|Transient
Interventions: DRUG: Intransal instillation of E-selectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Amrubicin Versus Topotecan in Patients With Small Cell Lung Cancer Who Have Responded to Prior Therapy.
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Amrubicin|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Multi-Patient Experimental Treatment Involving Allogeneic Human Mesenchymal Stem Cells (hMSCs) in Subjects With Acute Ischemic Stroke (EXPAND)
Status: TEMPORARILY_NOT_AVAILABLE
Conditions: Acute Ischemic Stroke|Mesenchymal Stem Cells|Stroke, Acute|Stroke/Brain Attack|Stroke, Ischemic
Interventions: DRUG: Allogeneic human mesenchymal stem cells (Allo-hMSCs)
Study Type: EXPANDED_ACCESS
Clinical trial: PAin During Shoulder Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Rotator Cuff Tendinopathy
Interventions: BEHAVIORAL: Pain Allowing Program (PAllow)|BEHAVIORAL: Pain Avoiding Program (PAvoid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levocarnitine in Treating Fatigue in Cancer Patients
Status: COMPLETED
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: levocarnitine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Stage II Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8
Interventions: DRUG: Apalutamide|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Gallium Ga 68 Gozetotide|RADIATION: Guided Stereotactic Body Radiation Therapy|PROCEDURE: Multiparametric Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 48-Week (24-Week Baseline Followed by a 24-Week Treatment) Phase II Pilot Study of the Tolerability and Effect/Efficacy of Subcutaneously Administered Insulin-Like Growth Factor-1 (rhIGF) (CEP-151) in Multiple Sclerosis (MS) Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: rhIGF-1 (CEP-151)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prevention of Relapse With Injectable Paliperidone Palmitate Versus Oral Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate injection|DRUG: oral antipsychotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study Evaluating the Safety of AC-170 0.24%
Status: COMPLETED
Conditions: Atopic Disease (Including Allergic Conjunctivitis)
Interventions: DRUG: Drug: AC-170 0.24%|DRUG: AC-170 0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants
Status: RECRUITING
Conditions: Genetic Predisposition to Disease|Hereditary Diseases
Interventions: GENETIC: Genome Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Phase 1 Study of Dimethandrolone Undecanoate in Healthy Men
Status: COMPLETED
Conditions: Healthy Men|Male Contraception
Interventions: DRUG: Dimethandrolone Undecanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise on Cardiometabolic Risk Factors in Type II Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: High-intensity interval training|BEHAVIORAL: Moderate intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Childhood Acute Basophilic Leukemia|Childhood Acute Eosinophilic Leukemia|Childhood Acute Erythroleukemia (M6)|Childhood Acute Megakaryocytic Leukemia (M7)|Childhood Acute Minimally Differentiated Myeloid Leukemia (M0)|Childhood Acute Monoblastic Leukemia (M5a)|Childhood Acute Monocytic Leukemia (M5b)|Childhood Acute Myeloblastic Leukemia With Maturation (M2)|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)|Childhood Acute Myelomonocytic Leukemia (M4)|Recurrent Childhood Acute Myeloid Leukemia|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Tislelizumab（neoadjuvant）|DRUG: Cisplatin （neoadjuvant）|DRUG: Nab-paclitaxel （neoadjuvant）|PROCEDURE: Surgical resection|DRUG: Cisplatin（adjuvant）|DRUG: Tislelizumab（adjuvant）|RADIATION: Radiation|DRUG: Carboplatin（neoadjuvant）|DRUG: Carboplatin（adjuvant）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Obturator Nerve Block With Ultrasound Guidance and Anatomical Signs
Status: UNKNOWN
Conditions: Succesful Obturator Nerve Block|Bladder Tumor|Bleeding
Interventions: PROCEDURE: obturator nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Arsenic Trioxide and Dexamethasone in Treating Patients With Recurrent or Refractory Stage II or Stage III Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: arsenic trioxide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Treatments on Posture and Balance in Elderly Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: OTHER: Strengthening and balance exercises|OTHER: Stretching and balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Patients With Mild to Moderate Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Placebo|DRUG: Masitinib (4.5)|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study for Patients With Follicular Lymphoma Needing Treatment
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: PROCEDURE: CHVP + interferon|DRUG: fludarabine|PROCEDURE: CHOP + TBI and autotransplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: F-18 AV-45|DRUG: F-18-THK-5351
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Sclerosis, Systemic
Interventions: DRUG: Placebo|DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fat and Sugar Metabolism During Exercise in Patients With Metabolic Myopathy
Status: UNKNOWN
Conditions: Metabolism, Inborn Errors|Lipid Metabolism, Inborn Errors|Carbohydrate Metabolism, Inborn Errors|Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency|Glycogenin-1 Deficiency (Glycogen Storage Disease Type XV)|Carnitine Palmitoyl Transferase 2 Deficiency|VLCAD Deficiency|Medium-chain Acyl-CoA Dehydrogenase Deficiency|Multiple Acyl-CoA Dehydrogenase Deficiency|Carnitine Transporter Deficiency|Neutral Lipid Storage Disease|Glycogen Storage Disease Type II|Glycogen Storage Disease Type III|Glycogen Storage Disease Type IV|Glycogen Storage Disease Type V|Muscle Phosphofructokinase Deficiency|Phosphoglucomutase 1 Deficiency|Phosphoglycerate Mutase Deficiency|Phosphoglycerate Kinase Deficiency|Phosphorylase Kinase Deficiency|Beta Enolase Deficiency|Lactate Dehydrogenase Deficiency|Glycogen Synthase Deficiency
Interventions: OTHER: Sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone Acetate in Male Participants With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone|DRUG: Leuprolide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Reported Outcome on Genital Sensitivity and Sexual Function After Genital Gender Affirming Surgery
Status: RECRUITING
Conditions: Gender Dysphoria
Interventions: DIAGNOSTIC_TEST: Semmes-Weinstein monofilament testing and questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Irinotecan, Oxaliplatin and Cetuximab for Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Irinotecan, oxaliplatin, and cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Emtricitabine/Tenofovir disoproxil fumarate|DRUG: Tenofovir disoproxil fumarate|DRUG: Zidovudine|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)
Status: COMPLETED
Conditions: Nontuberculous Mycobacteria|Mycobacterium Avium Complex
Interventions: DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Breathing With and Without Abdominal Muscles Strength Training Program
Status: COMPLETED
Conditions: Pelvic Floor Muscle Weakness|Endurance|Quality of Life
Interventions: OTHER: Diaphragmatic breathing exercises|OTHER: Abdominal muscle strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Bavituximab, Axitinib, and Avelumab in Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Axitinib|DRUG: Avelumab|DRUG: Bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of TEAS Combined With Oxycodone on Postoperative Visceral Pain in Gynecologic Laparoscopic Patients
Status: RECRUITING
Conditions: Visceral Pain
Interventions: OTHER: TEAS|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Management of Symptomatic Pelvic Organ Prolapse Using Vaginal Pessaries: Generation of a Standardized Management Protocol
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse|Quality of Life
Interventions: DEVICE: Vaginal Pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving End of Life Care in Head and Neck Cancer
Status: TERMINATED
Conditions: The Families or Next of Kin of Patients Treated at MSKCC for Non-cutaneous Squamous Cell Carcinomas of the|Upper Aerodigestive Tract
Interventions: BEHAVIORAL: The The Family Assessment of Treatment at the End of life (FATE ) survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation
Status: COMPLETED
Conditions: Trauma Injury
Interventions: BIOLOGICAL: Cryoprecipitate|BIOLOGICAL: Red Blood Cells|BIOLOGICAL: Plasma|BIOLOGICAL: Platelets|BIOLOGICAL: Whole Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wellness Effects of Animal-assisted Activities With Autism Spectrum Disorder Youth in a Specialized Psychiatric Hospital
Status: COMPLETED
Conditions: Child Behavior|Autism Spectrum Disorder|Psychiatric Hospitalization|Veterinary Therapeutics
Interventions: OTHER: Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of the Perception of a Needle Injection Pain Between Cancer Patients Receiving Opioid Therapy Versus Opioid-naive Patients
Status: COMPLETED
Conditions: Cancer Patients
Interventions: PROCEDURE: The local anesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Evaluate Nitazoxanide for Treatment of Mild COVID-19 in Subjects Not at High Risk of Severe Illness
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Nitazoxanide|DRUG: Placebo|DIETARY_SUPPLEMENT: Vitamin Super-B Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heat Strain Prevention in Elderly Agricultural Workers
Status: RECRUITING
Conditions: Heat Stress Disorders|Heat Stroke|Heat Exhaustion|Heat Cramps
Interventions: OTHER: Sustainable Heat Strain Prevention Program for Agricultural Elderly Workers (SHiP-AEW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy
Status: COMPLETED
Conditions: Patellar Tendinopathy / Jumpers Knee
Interventions: PROCEDURE: peritendinous corticosteroid injections|PROCEDURE: eccentric decline squat training|PROCEDURE: heavy slow resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intercare, Mindfulness and Compassion Based Intervention for Parental Burnout
Status: RECRUITING
Conditions: Parental Burnout|Burnout, Caregiver|Burnout
Interventions: BEHAVIORAL: Mindfulness and Compassion based Intercare program for parental burnout reduction (IBAP-BP)|BEHAVIORAL: Educational material|BEHAVIORAL: Reminder by email|BEHAVIORAL: Whatsapp support group|BEHAVIORAL: Journaling|BEHAVIORAL: Guided relaxation excercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Arm Assisted Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis
Interventions: DEVICE: Robotic Arm Assisted Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma|Recurrent Follicular Lymphoma|Refractory Follicular Lymphoma
Interventions: DRUG: Bendamustine Hydrochloride|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|PROCEDURE: Echocardiography|DRUG: Lenalidomide|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Obinutuzumab|PROCEDURE: Positron Emission Tomography|DRUG: Prednisone|DRUG: Umbralisib|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Modification of Attention Bias Remotely After Trauma
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: SMART Mobile App - Attention Bias Modification|DEVICE: SMART Mobile App - Attention Control Training|DEVICE: SMART Mobile App - Placebo Training|DEVICE: SMART Mobile App - Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two Week Study Evaluating Safety, Tolerability and Pharmacokinetics of Multiple Doses of JTK-853 in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: JTK-853, ketoconazole|DRUG: JTK-853 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Capecitabine, and Bevacizumab in Treating Patients With Pancreatic Cancer That Can Be Removed By Surgery
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: gemcitabine hydrochloride|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: computed tomography|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research Study to Evaluate the Stain Removal Efficacy
Status: COMPLETED
Conditions: Tooth Stain Removal
Interventions: DRUG: Stannous Fluoride Toothpaste (SnF)|DRUG: Colgate Fluoride Toothpaste (CDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Impact of Two Posters on Contraceptive Knowledge, Contraceptive Preferences, and Perceived Pregnancy Risk
Status: COMPLETED
Conditions: Contraception|Knowledge, Attitudes, Practice
Interventions: OTHER: View CDC Poster|OTHER: View Patient-Centered Poster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard
Status: RECRUITING
Conditions: Chest Pain|Stenosis|Myocardial Ischemia
Interventions: DEVICE: Magnetocardiography|DEVICE: Single photon emission computed tomography (SPECT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IMCY-0141 Safety and Efficacy in Multiple Sclerosis - ISEMIS Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: IMCY-0141|DRUG: Placebo|DRUG: Dimethyl Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Anxiety
Interventions: OTHER: TiMBRe|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate of the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Acneiform Rash
Status: TERMINATED
Conditions: Acneiform Eruptions
Interventions: BIOLOGICAL: Imsidolimab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STRONG Program for Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: BEHAVIORAL: Consultations with Moffitt Dietician|BEHAVIORAL: Daily Food Intake Diary with Fitbit smartphone application|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Comparison of Oral Intubation Via - Ambu® Aura Gain™ vs Slotted Guedel Tubus
Status: COMPLETED
Conditions: Adverse Anesthesia Outcome
Interventions: PROCEDURE: AuraGain|PROCEDURE: Slotted Guedeltubus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carboxyamidotriazole in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: carboxyamidotriazole|OTHER: placebo|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Tacrolimus (reduced tacrolimus)|DRUG: Tacrolimus (tacrolimus elimination)|DRUG: Tacrolimus (tacrolimus control)|DRUG: Everolimus (reduced tacrolimus)|DRUG: Everolimus (tacrolimus elimination)|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Education for South Asians With Asthma and Their Clinicians Reduce Unscheduled Care? A Randomised Trial
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: PACE (Professional Asthma Care Education)|BEHAVIORAL: Lay Led Expert Patient Programme|BEHAVIORAL: Asthma self management education by a specialist nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis With Polyposis|Chronic Hyperplastic Sinusitis
Interventions: DRUG: Tranexamic Acid|DRUG: Normal Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: MDT-2111 TAVI 23 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Pilot Study to Assess Differences in Stimulation Induced Paresthesia Between 2 Spinal Cord Stimulation Systems
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DEVICE: Treatment with the Axium SCS system|DEVICE: Treatment with the Medtronic SCS System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia
Status: RECRUITING
Conditions: Cognitive Decline|Cognitive Impairment|Dementia
Interventions: COMBINATION_PRODUCT: FINGER 2.0 multidomain lifestyle-based intervention|OTHER: Self-guided multidomain lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcomes in Patients With Infection by Resistant Microorganism
Status: ENROLLING_BY_INVITATION
Conditions: Pneumonia|Bloodstream Infection|Urinary Tract Infections|Skin Infection|Surgical Site Infection|Staphylococcus Aureus|Klebsiella Pneumonia|Escherichia Coli|Enterococcus Faecium Infection|Acinetobacter Infections|Pseudomonas Aeruginosa
Interventions: OTHER: Pathogen resistant phenotype
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride Solution
Status: COMPLETED
Conditions: Caries Arrested
Interventions: DRUG: Silver diamine fluoride|DRUG: Sodium fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors
Status: RECRUITING
Conditions: Localized Prostate Carcinoma|Locally Advanced Prostate Carcinoma|Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage II Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Discussion|OTHER: Exercise Intervention|OTHER: Interview|OTHER: Medical Device Usage and Evaluation|PROCEDURE: Physical Examination|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration|OTHER: Recreational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Impact of the PRONEtect Education Hub vs. Classic Lecture, on the Competencies of Nursing Students
Status: COMPLETED
Conditions: Prone Position|Pressure Ulcer
Interventions: OTHER: (online) PRONEtect educational material|OTHER: Classic (normal) one hour lesson/lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program
Status: COMPLETED
Conditions: Harm Reduction|HIV Infections|Drug Use
Interventions: DRUG: Biktarvy 50Mg-200Mg-25Mg Tablet|OTHER: HIV care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate vs Placebo for Placental Abruption
Status: COMPLETED
Conditions: Abruptio Placentae
Interventions: DRUG: Magnesium Sulfate|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multifidus Plane Block Versus Caudal Block for Hypospadias
Status: NOT_YET_RECRUITING
Conditions: Hypospadias|Caudal Block
Interventions: PROCEDURE: Multifidus plane block|PROCEDURE: caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools
Status: RECRUITING
Conditions: Sensorineural Hearing Loss|Fibrosis
Interventions: PROCEDURE: Transimedance Matrix measurements|PROCEDURE: Depth sounding and spectroscopy|PROCEDURE: Cone Beam Computer Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine Gliomas
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma
Interventions: PROCEDURE: adjuvant therapy|BIOLOGICAL: pegylated interferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation
Status: COMPLETED
Conditions: Invasive Candidiasis
Interventions: DRUG: Micafungin|DRUG: Micafungin|DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study (Telmisartan, Amlodipine, Chlorthalidone)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Amlodipine|DRUG: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology
Status: RECRUITING
Conditions: Bladder Squamous Cell Carcinoma|Locally Advanced Bladder Carcinoma|Malignant Renal Pelvis Neoplasm|Malignant Ureter Neoplasm|Malignant Urethral Neoplasm|Metastatic Bladder Carcinoma|Stage III Bladder Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Unresectable Bladder Carcinoma|Urachal Adenocarcinoma|Bladder Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Enfortumab Vedotin|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up During the Peripubertal Period of Preterm Children Included in the Protocol Entitled "EPIPOD".
Status: RECRUITING
Conditions: Preterm Children
Interventions: OTHER: clinical and biological measurements and questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Impact of Early Physiotherapy on Lymphatic Dysfunction in Head and Neck Cancer Survivorship
Status: ENROLLING_BY_INVITATION
Conditions: Lymphedema of Face|Head and Neck Cancer
Interventions: COMBINATION_PRODUCT: Near-infrared fluorescence lymphatic imaging|DEVICE: advanced pneumatic compression therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Clinical Activity of UCART123 in Patients With BPDCN
Status: TERMINATED
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Interventions: BIOLOGICAL: UCART123
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Enzalutamide|DRUG: Mifepristone|DRUG: TPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Assisted Orthognathic Surgery. Facial Asymmetry
Status: COMPLETED
Conditions: Facial Asymmetry
Interventions: PROCEDURE: classic procedure of planning|PROCEDURE: computer assisted orthognathic planning and surgery of asymmetric patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Innovation in NOn Invasive Ventilation in COPD Patients Treated by Long Term Oxygen Therapy
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: NIV Device + LTOT|DEVICE: LTOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms
Status: TERMINATED
Conditions: Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects
Interventions: OTHER: KB109|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Angiotensin Converting Enzyme Inhibitor, Lisinopril, on Renal Blood Flow and Its Correlation With Proteinuria Reduction in Subjects With Type 2 Diabetes and Kidney Disease
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: ACEI or ARB|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR Antagonist and STRIATIN
Status: COMPLETED
Conditions: Hypertension|Genetics Hypertension
Interventions: DRUG: Eplerenone vs Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Pediatric T1D - 4T Study
Status: ENROLLING_BY_INVITATION
Conditions: Type1diabetes
Interventions: BEHAVIORAL: 4T Education and Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laryngeal Reflex Study Under Propofol Anesthesia: Effect of Intravenous Lidocaine
Status: COMPLETED
Conditions: Laryngospasm
Interventions: DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Memory Preoperative Preparation Reduce Post Operative Behavioral Change
Status: UNKNOWN
Conditions: Behavior|Agitation
Interventions: OTHER: Preoperative video information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of an Epilepsy Application for Self-management in Viet Nam
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: OTHER: Epilepsy application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OSCAR - An Internet-based Supportive Coaching for Informal Caregivers of Adult Individuals With an Acquired Brain Injury
Status: TERMINATED
Conditions: Caregivers|Brain Injury
Interventions: BEHAVIORAL: Internet-based supportive coaching OSCAR|OTHER: Waiting-list control group (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of DLBS-32 in Subjects With Type-II Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DLBS-32|DRUG: DLBS-32|DRUG: DLBS-32|DRUG: DLBS-32|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot
Status: COMPLETED
Conditions: Subtle Cavus Foot|Mechanical Foot Pains|Plantar Fasciitis|Achilles Tendinopathy|Insertional Achilles Tendinopathy|Strain of Peroneal Tendon|Metatarsalgia|Pes Cavus|Pes Cavus, Bilateral|Pes Cavovarus
Interventions: DEVICE: Specifically optimized off-the-counter foot orthosis (Medical grade foot orthosis)|DEVICE: Plain off-the-counter foot orthosis (Medical grade foot orthosis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CDL Validation Study
Status: COMPLETED
Conditions: Eyes Dry Chronic|Chronic Conjunctivitis of Both Eyes|Limbal Stem-cell Deficiency|Eye Lesion|Eye Disease; Cataract|Eyes Dry Feeling of|Cornea Disease|Cornea Inflamed|Cornea; Injury, Abrasion|Cornea Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients
Status: COMPLETED
Conditions: Single Ventricle
Interventions: DRUG: Tadalafil Citrate|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Central and Cerebral Circulation in Early Stages After LVAD Implantation
Status: UNKNOWN
Conditions: Heart Failure, Left-Sided|Heart Failure, Right-Sided
Interventions: DEVICE: LVAD flow velocity setting-Rounds per Minute(RPM) on HeartMate III®|DRUG: MAP intervention using Noradrenalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma
Status: UNKNOWN
Conditions: Osteosarcoma
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection
Status: UNKNOWN
Conditions: Portal Hypertension
Interventions: DRUG: Somatostatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease
Status: RECRUITING
Conditions: Von Willebrand Diseases
Interventions: DRUG: VGA039|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Stimulation to Trigger Adipose Loss Clinical Trial
Status: TERMINATED
Conditions: Obesity|Obesity, Abdominal|Metabolic Syndrome|Weight Loss
Interventions: DEVICE: Vestibular nerve stimulator|DEVICE: Sham vestibular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Study Using Bevacizumab for Patients With Adrenocortical Carcinoma
Status: WITHDRAWN
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT