pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Investigate the Safety and Efficacy of YY003 in Adults With Moderate to Severe Glabellar Lines
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: YY003|BIOLOGICAL: Vehicle Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Electrical Stimulation on Gastroesophageal Reflux Disease (GERD) in Patients After Sleeve Gastrectomy
Status: UNKNOWN
Conditions: GERD|Sleeve Gastrectomy
Interventions: DEVICE: LES-Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim
Status: TERMINATED
Conditions: Severe Combined Immunodeficiency
Interventions: DRUG: Transplant Conditioning with Mobilization Only|DRUG: Transplant Conditioning with Mobilization and Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function
Status: UNKNOWN
Conditions: Coronary Endothelial Function
Interventions: DRUG: Byetta (Exenatide)|DRUG: Glucophage ( Metformin Hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Vagus Nerve Stimulation for Language Recovery After Stroke
Status: NOT_YET_RECRUITING
Conditions: Aphasia|Chronic Stroke
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation|DEVICE: Sham Transcutaneous Vagus Nerve Stimulation|BEHAVIORAL: Computer Based Speech and Language Therapy (Step by Step)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Combined Care for Knee Replacement Patients
Status: NOT_YET_RECRUITING
Conditions: Arthroplasty, Knee Replacement
Interventions: BEHAVIORAL: combined care guidance|BEHAVIORAL: general care guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Media Parenting Prevention Intervention
Status: NOT_YET_RECRUITING
Conditions: Substance Related Problem
Interventions: BEHAVIORAL: Intervention Arm - T.E.C.H. Parenting|BEHAVIORAL: Control Arm - General Positive Parenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transforming Hemodialysis-Related Vascular Access Education
Status: RECRUITING
Conditions: Chronic Kidney Disease|Hemodialysis Vascular Access
Interventions: BEHAVIORAL: Educational Materials|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Usual Care|OTHER: Patient Lists for Clinicians: System-Level Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exploring Prolonged AMR in ACL Reconstructed Patients
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|ACL|ACL Injury|ACL Tear|Anterior Cruciate Ligament Reconstruction|Arthrogenic Muscle Inhibition|Arthrogenic Muscle Responses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surveillance and Proactive Intervention for Dialysis Access
Status: WITHDRAWN
Conditions: Renal Failure|Arteriovenous Fistula
Interventions: PROCEDURE: Active ultrasound surveillance of fistula and proactive treatment of stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characteristics of Balance Control to Unexpected Loss of Balance During Standing and Walking in Post-stroke Individuals
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Stroke Subjects Perturbation-Based Balance Training|DEVICE: Stroke Subjects Weight Shifting and Gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency
Status: UNKNOWN
Conditions: Growth Hormone Deficiency
Interventions: BIOLOGICAL: PEG-somatropin|BIOLOGICAL: PEG-somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Value of Staging Laparoscopy and Computed Tomography Response Assessment in Patients With Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DIAGNOSTIC_TEST: Computed tomography|DIAGNOSTIC_TEST: Diagnostic laparoscopy with peritoneal lavage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Training for Diabetes Self-Management
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Memory, Attention, and Problem Solving Skills for Diabetes|BEHAVIORAL: Brain Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB)
Status: WITHDRAWN
Conditions: PTLD|Lymphoid Tumor|Hematopoietic/Lymphoid Cancer|Plasmacytic Hyperplasia PTLD|Infectious Mononucleosis|Florid Follicular Hyperplasia PTLD|Polymorphic PTLD|Monomorphic PTLD|Classical Hodgkin Lymphoma Type PTLD
Interventions: DRUG: Rituximab|DRUG: Brentuximab Vedotin|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Status Assessment of Pediatric Cystic Fibrosis Patients and Effect of Nutrition Education on Nutritional Status
Status: COMPLETED
Conditions: Cystic Fibrosis in Children
Interventions: BEHAVIORAL: Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants
Status: TERMINATED
Conditions: Cholera|Diarrhea|Vibrio Infections
Interventions: BIOLOGICAL: Peru-15 Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular Dystrophy
Status: UNKNOWN
Conditions: Duchenne Muscular Dystrophy|Cardiomyopathies
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy and Safety of Three W0027 Regimens in the Treatment of Moccasin Type Tinea Pedis (MTTP)
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: W0027|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Range Finding Study to Evaluate the Efficacy and Safety of AZD9668 Administered Orally at Three Dose Levels to Patients With Chronic Obstructive Pulmonary Disease (COPD) on Treatment With Tiotropium
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD9668|DRUG: AZD9668|DRUG: AZD9668|DRUG: AZD9668 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Hyperpolarized [1-13C]Pyruvate to Detect Cardiotoxicity
Status: ENROLLING_BY_INVITATION
Conditions: Breast Neoplasms
Interventions: DRUG: Formal study using hyperpolarized 13C-pyruvate injection|DRUG: Feasible study using hyperpolarized 13C-pyruvate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Trial of Optimizing Platinum-Based Chemotherapy Based on ERCC1 Expression as First-Line Treatment in Patients With Locally Advanced or Metastatic Gastric Cancer
Status: TERMINATED
Conditions: Stomach Neoplasms
Interventions: DRUG: Capecitabine+Cisplatin|DRUG: Docetaxel+Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Erlotinib an Epidermal Growth Factor Receptor (EGFR) Inhibitor in the Treatment of Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Safety, Tolerability, and Clinical Activity of Forimtamig-Based Treatment Combinations in Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Forimtamig|DRUG: Carfilzomib|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Group Education and Individual Counselling on Mental Health and Quality of Life in 45-60 Year Old Women
Status: COMPLETED
Conditions: Women's Health|Quality of Life|Mental Health|Menopause|Primary Health Care|Sick Leave
Interventions: BEHAVIORAL: Group information (GI)|BEHAVIORAL: Structured person-centered support (PCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laparoscopy to Detect Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: OTHER: Narrow Band Imaging (NBI)|OTHER: Standard White Light Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Laser Acupuncture Therapy on Paralytic Ileus
Status: UNKNOWN
Conditions: Paralytic Ileus
Interventions: DEVICE: Laser Acupuncture group|DEVICE: Sham Laser Acupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: DRUG: PF-06882961|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Music Interventions for Dementia and Depression in Elderly Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Dementia|Depression
Interventions: BEHAVIORAL: Group Music Therapy|BEHAVIORAL: Recreational Choir Singing|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: USPIO Enhanced MR Imaging in CNS Tumours (UMIC)
Status: RECRUITING
Conditions: Vestibular Schwannoma|Glioma, Astrocytic
Interventions: DIAGNOSTIC_TEST: USPIO enhanced MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Efficacy of Intracavernosal Infusion of PRP vs PPP for the Erectile Dysfunction.
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: PRP|DRUG: PPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nutritional Therapy With High Methionine Content in the Treatment of NAFLD
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: DIETARY_SUPPLEMENT: Experimental group (with diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Task or Virtual Reality Intervention for Improving UE Function
Status: TERMINATED
Conditions: Upper Extremity Paresis|Hemiplegia and/or Hemiparesis Following Stroke|Hemiplegic Cerebral Palsy
Interventions: BEHAVIORAL: Virtual Reality (A) then Task (B)|BEHAVIORAL: Task (B) then Virtual Reality (A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: JNT Versus TNT to Guided OGT-overlap Oesophagojejunostomy
Status: COMPLETED
Conditions: Gastric/Gastroesophageal Junction (g/Gej) Cancer
Interventions: PROCEDURE: JNT Guided OGT-overlap Oesophagojejunostomy|PROCEDURE: TNT Guided OGT-overlap Oesophagojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mortality and Changes in Quality of Life of Patients Suffering From SAH With Different Hydration Strategies
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Lactated Ringer's solution|DRUG: Hydroxyethyl starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Novel Urinary Access System for Universal Transcatheter Cystoscopy at The Time of Hysterectomy
Status: UNKNOWN
Conditions: Hysterectomy
Interventions: DEVICE: Novel urinary access system (CystoSureTM)|DEVICE: Standard Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: placebo|DRUG: pregabalin|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Derm-Maxx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health Assessment and Prescribing by Alberta Pharmacists
Status: RECRUITING
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder|Pharmacist-Patient Relations
Interventions: OTHER: Standard Pharmacist Care|OTHER: Reviewed Questionnaire tool results with participant|OTHER: Patient Clinical Assessment|OTHER: Psychotherapy Referral|OTHER: Pharmacist initiated interim telephone follow-up with participant|OTHER: Communication update with physician after participant contact|OTHER: Medication Counselling and Educational Support|OTHER: Non-medication Counselling|OTHER: Identification of drug interaction|OTHER: Identification of drug adverse effect|OTHER: Identification of severe deterioration|OTHER: Pharmacist-to-physician recommendation for medication adjustment, change to alternative, add-on, or deprescribing|OTHER: Pharmacist initiated medication adjustment, change to alternative, add-on, or deprescribing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism
Status: TERMINATED
Conditions: Hypothyroidism
Interventions: DRUG: Growth hormone|DRUG: Growth hormone treatment and puberty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: uPAR-PET for Prognostication in Patients With Non-small Cell Lung Cancer, Malignant Pleural Mesothelioma and Large Cell Neuroendocrine Carcinoma of the Lung
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Malignant Pleural Mesothelioma|Large Cell Neuroendocrine Carcinoma of the Lung
Interventions: OTHER: 68Ga-NOTA-AE105 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Deprescribing dRrugs for Overactive Bladder in General Practice (DROP)
Status: ENROLLING_BY_INVITATION
Conditions: Overactive Bladder|Deprescribing|PIMS
Interventions: OTHER: deprescribing-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Metatinib Tromethamine Tablet
Status: UNKNOWN
Conditions: Advanced or Metastatic Gastric Cancer|Advanced or Metastatic Liver Cancer|Advanced or Metastatic CRC|Advanced or Metastatic Non Squamous NSCLC
Interventions: DRUG: Metatinib Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy
Status: COMPLETED
Conditions: Insomnia|Cancer
Interventions: OTHER: Acupuncture|OTHER: Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Satisfaction of RHC Serum Combined With RHC(III) Injection
Status: NOT_YET_RECRUITING
Conditions: Facial Wrinkles
Interventions: PROCEDURE: Recombinant type III humanized collagen solution for injection|OTHER: SkinCeuticals recombinant humanized collagen (RHC) serum|OTHER: Regular face cream smear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose Study of RhuMab 2C4 and Docetaxel in the Treatment of Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Docetaxel|DRUG: RhuMab 2C4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA)
Status: UNKNOWN
Conditions: Cerebral Amyloid Angiopathy
Interventions: DEVICE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine Treatment of Obesity With Type 2 Diabetes, Dyslipidemia
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus ;Obesity,High Triglycerides；TCM
Interventions: DRUG: Metformin|DRUG: Jiangtangtiaozhi decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19)
Status: TERMINATED
Conditions: Influenza|SARS (Severe Acute Respiratory Syndrome)|Respiratory Viral Infection|Respiratory Tract Infections|Infection, Bacterial|Infection Viral|Covid19|RNA Virus Infections
Interventions: BIOLOGICAL: Respiratory infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kochujang, a Fermented Soybean-based Red Pepper Paste, Decreases Visceral Fat and Improves Blood Lipid Profiles in Overweight Adults
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Kochujang|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Absorption, Distribution, Metabolism and Excretion of [14C]- Labeled BIA 5-453 and Metabolites
Status: COMPLETED
Conditions: Hypertension|Congestive Heart Failure
Interventions: DRUG: BIA-5-453
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate SBI in the Dietary Management of Mild to Moderate Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: OTHER: Serum-derived Bovine Immunoglobulin / Protein Isolate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Galunisertib and Paclitaxel in Treating Patients With Metastatic Androgen Receptor Negative (AR-) Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Galunisertib|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprainguinal Fascia Iliaca Block in Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia|Anesthesia, Local
Interventions: OTHER: control group; Patients who received physiological saline|OTHER: suprainguinal fascia block; Patients receiving local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: BIOLOGICAL: LP-001 Dose 1 (Single)|BIOLOGICAL: LP-001 Dose 2 (Single)|BIOLOGICAL: LP-001 Dose 3 (Single)|BIOLOGICAL: LP-001 Dose 4 (Single)|BIOLOGICAL: LP-001 Dose 5 (Single)|BIOLOGICAL: LP-001 Dose 6 (Single)|BIOLOGICAL: Placebo (Single)|BIOLOGICAL: LP-001 Dose 7 (Multiple)|BIOLOGICAL: LP-001 Dose 8 (Multiple)|BIOLOGICAL: Placebo (Multiple)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥50 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: mRNA-1345|BIOLOGICAL: Afluria® Quadrivalent|BIOLOGICAL: mRNA-1273.214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Low Back Pain|Fibromyalgia|Upper Extremity Dysfunction|Complex Regional Pain Syndromes|Phantom Limb Pain|Rheumatoid Arthritis|Carpal Tunnel Syndrome|Repetitive Strain Injury
Interventions: DEVICE: Karuna Labs Virtual Reality Software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
Status: COMPLETED
Conditions: Tonsillitis
Interventions: OTHER: Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HTD1801|DRUG: Placebo|DRUG: HTD1801
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
Status: COMPLETED
Conditions: Muscle Damage|Inflammation|Oxidative Stress|Functional Recovery
Interventions: DIETARY_SUPPLEMENT: P-CHO supplement|DIETARY_SUPPLEMENT: Fruit Milk Shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Increased Risk for Development of Breast Cancer
Interventions: DRUG: bazedoxifene plus conjugated estrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: efanesoctocog alfa (BIVV001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Ambrisentan 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases
Status: UNKNOWN
Conditions: Bone Metastases|Bone Neoplasm|Bone Cancer|Bone Lesion
Interventions: DEVICE: Thermal ablation of bone metastasis with MR-HIFU device Philips Sonalleve coupled with Philips Ingenia 3.0T|DEVICE: Varian Truebeam Radiotherapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dual-Site LV Pacing in CRT Non Responders: Multicenter Randomized Trial
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Additional Endocardial or Epicardial LV Lead|DEVICE: CRT-P or CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma (DIPG)|Brain Stem Glioma
Interventions: BIOLOGICAL: TTRNA-DC vaccines with GM-CSF|BIOLOGICAL: TTRNA-xALT|DRUG: Cyclophosphamide + Fludarabine Lymphodepletive Conditioning|DRUG: Dose-Intensified TMZ|DRUG: Td vaccine|BIOLOGICAL: Autologous Hematopoietic Stem Cells (HSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rabeprazole Extended-Release, 50 mg, Versus Esomeprazole, 40 mg, for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Rabeprazole sodium|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection
Status: COMPLETED
Conditions: Emergent Coronary Procedure
Interventions: DRUG: Sodium bicarbonate|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Urinary Retention in Orthopedic Patients
Status: COMPLETED
Conditions: Urinary Retention|Anesthesia, Spinal|Orthopedic Procedures|Nerve Block
Interventions: PROCEDURE: spinal anesthesia with morphine|PROCEDURE: spinal anesthesia without morphine + peripheral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance-Guided High Intensity Focused Ultrasound for Recurrent Rectal Cancer
Status: COMPLETED
Conditions: Recurrent Rectal Cancer
Interventions: DEVICE: Magnetic resonance-guided focused ultrasound|RADIATION: Standard Radiation|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer - Female|Breast Cancer - Male
Interventions: DRUG: Tamoxifen|DRUG: Ribociclib|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
Status: ENROLLING_BY_INVITATION
Conditions: Orchiectomy|Spermatic Cord Block|Spinal Anesthesia|Pain Score|Prostate Cancer
Interventions: PROCEDURE: bilateral orchiectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ten Days Sequential Treatment and Traditional Three Combined Treatment of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 5RA-5RCM|DRUG: 5RA-5RCT|DRUG: 10RCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motor Imagery Training in Addition to Core Stabilization Exercises on Core Performance, Balance, Functional Capacity, and Quality of Life in Healthy Adolescents Girls
Status: COMPLETED
Conditions: Adolescent
Interventions: OTHER: Motor Imagery Training|OTHER: Core Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting REhabilitation Delivery for Maximum Impact at Home
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Hip Osteoarthritis|Knee Osteoarthritis|Osteoarthritis|Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: BEHAVIORAL: progressive resistance exercise|BEHAVIORAL: self-management strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Study for Patient Perception of Treatment Satisfaction After Switching to Mirabegron in Patients With Overactive Bladder Who Were Unsatisfied With Efficacy of Antimuscarinic Therapy or Adverse Event.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: mirabegron 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Pessary for Prevention of Spontaneous Preterm Birth in Singleton Pregnancies With Arrested Preterm Labor
Status: TERMINATED
Conditions: Preterm Birth
Interventions: DEVICE: arabin pessary|DEVICE: no pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell|Oral Cancer|Oropharynx Cancer|Larynx Cancer|Lip Cancer|Esophageal Cancer
Interventions: DRUG: Durvalumab|DRUG: Carboplatin|DRUG: Nab-paclitaxel|DRUG: Cisplatin|PROCEDURE: Surgical resection|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Spirulina Maxima and Exercise on General Fitness and Blood Lipids in Older Adults
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Spirulina maxima supplementation|OTHER: Wash-out|OTHER: Placebo supplementation|OTHER: Isoenergetic diet|OTHER: Systematic physical exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia
Status: COMPLETED
Conditions: Essential Hypertension|Hypercholesterolemia
Interventions: DRUG: simvastatin|DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)
Status: COMPLETED
Conditions: Adenocarcinoma Gastric Stage IV With Metastases|Adenocarcinoma - GEJ
Interventions: DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess Pharmacodynamics, Safety And Tolerability Of PF-05221304 And PF-06865571 Co-Administered For 6 Weeks In Adults With Non-Alcoholic Fatty Liver Disease.
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: PF-05221304 Monotherapy|DRUG: PF-06865571 Monotherapy|DRUG: Placebo|DRUG: PF-05221304 and PF-06865571 Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Variants Associated With Low Back Pain and Their Response to Treatment With Duloxetine or Propranolol
Status: TERMINATED
Conditions: Low Back Pain
Interventions: DRUG: Duloxetine|DRUG: Propranolol|GENETIC: Genotype for SNPs associated to Serotonin and COMT|DRUG: Placebo Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Revascularization With ev3 Arterial Technology Evolution (CREATE) Trial
Status: COMPLETED
Conditions: Carotid Artery Disease
Interventions: DEVICE: PROTÉGÉ® GPS™ and PROTÉGÉ® RX Carotid Stent Systems and Spider Embolic Protection Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Multi-Cancer Populations With Correlation to Clinical, Molecular and Immunologic Parameters With DNA MethylaTION
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer|Renal Cell Carcinoma
Interventions: BIOLOGICAL: Durvalumab|BIOLOGICAL: Oleclumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DEVICE: Accu-Chek Insight Pump System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy
Status: COMPLETED
Conditions: Hypotension|Heart Failure
Interventions: DRUG: Dapagliflozin|DRUG: Sacubitril-Valsartan|DRUG: Beta blocker|DRUG: Mineralocorticoid Receptor Antagonist|DEVICE: Cardiac resynchronization therapy and/or implantable cardioverter defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anal HPV Infection and Risk for Anal High-grade Squamous Intraepithelial Lesion Among Thai MSM With Acute HIV Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: BEHAVIORAL: SEARCH010/RV254
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility Of Mutational Load As A Predictor For Endoscopic Treatment Response In Barrett's Esophagus
Status: COMPLETED
Conditions: Barretts Esophagus With Dysplasia|Intramucosal Adenocarcinoma
Interventions: OTHER: Study Driven Procurement of Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vegetable Offering in the Home Environment - Impact of Free Accessibility and Choice on Snack Vegetable Intake
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: BEHAVIORAL: Vegetable variety|BEHAVIORAL: Vegetable offering strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Romidepsin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Promyelocytic Leukemia (M3)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Single Dose Alprostadil Cream (2 Concentrations Enhancer) to Vehicle in Men w/Erectile Dysfunction
Status: TERMINATED
Conditions: Erectile Dysfunction
Interventions: DRUG: WC3036-11F/Alprostadil in Vehicle 2.5%|DRUG: WC3036-12F/Alprostadil in Vehicle 0.5%|DRUG: WC3036-13P/Vehicle Only 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia
Status: TERMINATED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: Endovascular peripheral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash
Status: COMPLETED
Conditions: Oral Hygiene|Toothbrushing|Dental Plaque
Interventions: DEVICE: the toothpaste is used with a standard toothbrush without any claims 3 times a day after the main meals for 28 days.|DEVICE: the mint toothpaste and mouthwash are used with the scalar toothbrush 33 medium with antibacterial " Spazzolino tau-marin®" 3 times a day after the main meals for 28 days.|DEVICE: subjects of this group will use their routine oral hygiene products.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of dAroLutamide Addition to anDrogen Deprivation Therapy and radIatioN Therapy in Newly Diagnosed Prostate Cancer With Pelvic Lymph Nodes Metastases
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide 300 mg|DRUG: Placebo of Darolutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Younger Leukemia and Lymphoma Survivors
Status: COMPLETED
Conditions: Anxiety Disorder|Cancer Survivor|Fatigue|Leukemia|Long-term Effects Secondary to Cancer Therapy in Adults|Lymphoma|Lymphoproliferative Disorder|Pain|Psychosocial Effects of Cancer and Its Treatment|Small Intestine Cancer
Interventions: BEHAVIORAL: telephone-based intervention|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: fatigue assessment and management|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short and Long Term Effects of IASTM and ESWT Therapy in Individuals With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: IASTM|OTHER: ESWT|OTHER: Home Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Exposure of Simulated Hypoxia on Cardiac Output
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Simulated Altitude (FiO2: 15.1)|DEVICE: Shamed Hypoxia (FiO2: 20.9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients
Status: RECRUITING
Conditions: Neuromuscular Diseases|Hemiparesis|Charcot-Marie-Tooth Disease
Interventions: OTHER: Posturological examination on KPlates and AMTI platforms|OTHER: Berg Balance Scale (BBS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related Symptoms
Status: RECRUITING
Conditions: Immunoglobulin E-Mediated Food Allergy|Immunoglobulin G4-Related Disease|Symptoms and Signs|Adverse Reaction to Food
Interventions: DIAGNOSTIC_TEST: Food-specific Immunoglobulin G4 and/or Immunoglobulin E antibody reactions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study in Chinese Subjects With Chemotherapy Naïve Stage IV Melanoma Receiving Ipilimumab (3 mg/kg) vs. Dacarbazine
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Chiropractic Treatment for Low Back Pain and Smoking Cessation in Military Active Duty Personnel.
Status: COMPLETED
Conditions: Lower Back Pain
Interventions: OTHER: Medical Care + Chiropractic Care|OTHER: Conventional Medical Care Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Corona Virus on Intravitreal Injections
Status: UNKNOWN
Conditions: Diabetic Macular Edema|Age-Related Macular Degeneration|Choroidal Neovascularization|Myopic Choroidal Neovascularisation|Diabetic Retinopathy
Interventions: DRUG: Anti-vascular endothelial growth factors (Anti-VEGFs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Differential Biology of Benign and Malignant Renal Masses Using Advanced Magnetic Resonance Imaging Techniques
Status: RECRUITING
Conditions: Kidney Cancer
Interventions: DEVICE: Hyperpolarised MRI|DEVICE: Sodium MRI|DEVICE: Deuterium metabolic imaging (DMI) MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Contribution of Intraoperative Scans Coupled With the Navigation for the Precision of the Positioning of the Pedicle Screws During a Lumbar Spine Surgery: a Prospective Randomised Study
Status: UNKNOWN
Conditions: Lumbar Disc Disease|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Spine surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Determination of Core Body Temperature in Parturient Warmed With Upper or Underbody Forced Air Cover (Bair Hugger)
Status: RECRUITING
Conditions: Cesarean Section
Interventions: PROCEDURE: Upper Body Forced Air Warming device|PROCEDURE: Under Body Forced Air Warming device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Docetaxel, Doxorubicin, and Cyclophosphamide in Treating Women With Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Status: RECRUITING
Conditions: Acute Gout Flare|Gout Attack|Gout Flare|Gouty Arthritis|Gout|Arthritis|Joint Pain
Interventions: DRUG: Dapansutrile|OTHER: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L-citrulline Supplementation, Cold Exposure, & Post-Exercise Muscle Ischemia
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: L-citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Paravertebral Catheters for VATS Procedures
Status: COMPLETED
Conditions: Acute Pain
Interventions: DEVICE: Paravertebral catheter|DEVICE: opioid iv pca|DRUG: Ropivacaine|DEVICE: Elastomeric Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polio Vaccine (IPV) for SARS-CoV-2 and Prevention of Coronavirus Disease (COVID-19)
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: Vaccinated with polio vaccine (IPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION