pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Perceived Stress and Black Rice (Oryza Sativa L.) Extract Fermented With Lactobacillus
Status: COMPLETED
Conditions: Perceived Stress
Interventions: DIETARY_SUPPLEMENT: Fermented rice|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Individualized Treatment for Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: naltrexone|DRUG: naltrexone|BEHAVIORAL: Broad Spectrum Treatment|BEHAVIORAL: Motivational Enhancement Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq
Status: COMPLETED
Conditions: Turner Syndrome|Renal Insufficiency, Chronic|Pituitary Diseases|Dwarfism
Interventions: DRUG: Somatropin (rDNA origin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study Assessing the Ocular and Systemic Safety and Tolerability of OC-10X
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy (PDR)
Interventions: DRUG: OC-10X
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug Resistance
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Ritonavir|DRUG: Saquinavir|DRUG: Tenofovir disoproxil fumarate|DRUG: Amprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of E2007 On Pharmacodynamic Responses To Levodopa Among Patients With Parkinson's Disease Who Experience Dyskinesia And Motor Fluctuations
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: E2007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing BL-B01D1 With Physician's Choice of Chemotherapy in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: BL-B01D1|DRUG: capecitabine|DRUG: gemcitabine|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TELEMEDICINE,Maintenance of a Respiratory Rehabilitation Program in Patients With Chronic Obstructive Pulmonary Disease.
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: Telemedicine: Maintenance Respiratory Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Care of Older Adults With Chronic Heart Failure: A Comparative Effectiveness Clinical Trial (I-COACH)
Status: TERMINATED
Conditions: Heart Failure
Interventions: OTHER: Provider-Based Care Model Arm|BEHAVIORAL: mHealth Model Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: alpelisib|DRUG: placebo|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Plasticity of Human Predictive Coding Through Neuromodulation
Status: RECRUITING
Conditions: Human Brain and Cognition
Interventions: PROCEDURE: Occipital tACS at IAF-2Hz|PROCEDURE: Occipital tACS at IAF+2Hz|PROCEDURE: Frontal tACS at 4-7 Hz|PROCEDURE: Occipital tRNS|PROCEDURE: Frontal tRNS|PROCEDURE: Sham/placebo tACS|PROCEDURE: Sham/placebo tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three
Status: COMPLETED
Conditions: To Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual Acuity
Interventions: OTHER: Implantation of a multifocal Intraocular lens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the AeriSeal System Treatment in Patients With Advanced Non-Upper Lobe Predominant Heterogeneous Emphysema
Status: WITHDRAWN
Conditions: Emphysema|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: AeriSeal Emphysematous Lung Sealant Syst
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural and Pharmacological Correlates of Intrusions in Patients With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: 10 mg HydrocortisoneHöchst|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tube Tip Position in Orally Intubated 0-4year Old Children: Assessment of the Precision of Two Clinical Techniques
Status: COMPLETED
Conditions: Intubation, Endotracheal
Interventions: PROCEDURE: Anesthesia induction|PROCEDURE: Anesthesia induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteers
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Placebo IV Solution|DRUG: Debio 1450 IV Solution|DRUG: Placebo Tablet or Capsule|DRUG: Debio 1450 Tablet|DRUG: Debio 1450 Capsule|DRUG: Debio 1450 Oral Solution|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Anxiety in Parkinson's Disease With a Multi-Strain Probiotic
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Anxiety
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ryanodex as Adjuvant Treatment in Subjects With Psychostimulant Drug-Induced Toxicity (PDIT)
Status: TERMINATED
Conditions: Drug Toxicity Psychotropic Agents Psychostimulants
Interventions: DRUG: Ryanodex (dantrolene sodium) for injectable suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
Status: RECRUITING
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: BIOLOGICAL: quaratusugene ozeplasmid|DRUG: osimertinib|DRUG: Platinum-Based Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of Non Surgical Retreatment and Endodontic Surgery of Failed Root Canal Treated Teeth
Status: UNKNOWN
Conditions: Root Canal Therapy|Periapical Periodontitis
Interventions: PROCEDURE: surgical treatment|PROCEDURE: Non surgical retreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccine
Status: COMPLETED
Conditions: Cholera|Diarrhea|Vibrio Infections
Interventions: BIOLOGICAL: Killed bivalent whole cell oral cholera vaccine|BIOLOGICAL: Heat Killed E. coli Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Intravenous Remodulin in Patients in India With Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Remodulin (treprostinil sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ICVAX as a HIV Therapeutic DNA Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus|Human Immunodeficiency Virus I Infection
Interventions: BIOLOGICAL: ICVAX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Warming in Preterm Infants to Decrease Hypothermia
Status: RECRUITING
Conditions: Preterm Birth|Blood Transfusion Complication|Hypothermia
Interventions: DEVICE: Ranger blood warmer (3M Healthcare, Oakdale, Minnesota)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DZX Mediated Insulin Suppression in Obese Men
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: Diazoxide|DRUG: Metformin + Diazoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Status: UNKNOWN
Conditions: Branch Retinal Artery Occlusion|Central Retinal Artery Occlusion|Branch Retinal Vein Occlusion|Central Retinal Vein Occlusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)
Status: RECRUITING
Conditions: Stroke, Ischemic|Intravascular Thrombosis|Mechanical Thrombectomy
Interventions: DRUG: Intra-arterial administration of neuroprotective agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ursolic Acid Administration on Insulin Sensitivity and Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Ursolic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Paranoia in Schizophrenia
Status: COMPLETED
Conditions: Paranoid Delusions
Interventions: BEHAVIORAL: Paranoia-Focused Cognitive Behavioral Therapy (PFCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Thickness Changes With Scleral Contact Lenses
Status: UNKNOWN
Conditions: Keratoconus|Healthy Controls
Interventions: DEVICE: ZenLens™|DEVICE: Zen™ RC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of First Year Implementation of Komtü Programme to Improve Emotional Well-being in School.
Status: ENROLLING_BY_INVITATION
Conditions: Psychological Well-Being|Mental Health Wellness
Interventions: BEHAVIORAL: Komtü Programme (Komtü)|BEHAVIORAL: Komtü Training and Reflective Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Aspirin Versus Placebo in Resected Colon Cancer With PI3K Mutation Stage III or II High Risk
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: aspirin intake|DRUG: placebo intake|PROCEDURE: Surgical resection of colonic adenocarcinoma stage III or II high risk|BIOLOGICAL: Molecular analysis of exon 9 and 20 of PI3K|BIOLOGICAL: blood intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School Health Implementation Network: Eastern Mediterranean
Status: COMPLETED
Conditions: Behavioral Symptoms|Behavioral Problem|Emotional Problem|Emotional Stress|ADHD|Emotional Disorder|Depression, Anxiety|Conduct Disorder|Emotional Trauma
Interventions: BEHAVIORAL: WHO School Mental Health Program|BEHAVIORAL: Enhanced School Mental Health Program (eSMHP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Physical Effects of Systane(R) Lubricant Eye Drops Compared to Refresh Tears(R) Lubricant Eye Drops
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Systane|OTHER: Refresh Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Culture and Well-Being for Latinos
Status: RECRUITING
Conditions: Social Isolation|Loneliness|Suicidal Ideation
Interventions: BEHAVIORAL: Social Engage (S-ENGAGE)|BEHAVIORAL: The Healthy Lifestyles Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combined Autologous Cytokine-induced Killer Cells in Naive Stage IV EGFR-wild Type Lung Adenocarcinoma
Status: TERMINATED
Conditions: Lung Adenocarcinoma
Interventions: BIOLOGICAL: CIK|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HepatoPredict Prognostic Tool for the Decision of Liver Transplant in Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma, Scirrhous|Recurrence Tumor
Interventions: PROCEDURE: liver transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Status: COMPLETED
Conditions: Herniated Lumbar Disc
Interventions: DEVICE: Mechanical epidural neuroplasty|DRUG: Transforaminal epidural compound betamethasone injection|DRUG: Caudal epidural compound betamethasone injection|DRUG: Epidural hyaluronidase injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Uncontrolled DCD Kidneys REconditioned by a Novel Ex-VIVo Perfusion MEthod
Status: NOT_YET_RECRUITING
Conditions: End-Stage Kidney Disease
Interventions: OTHER: uDCD treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet Cognitive Behavior Therapy (CBT) for Body Dysmorphic Disorder (BDD)
Status: COMPLETED
Conditions: Body Dysmorhpic Disorder
Interventions: BEHAVIORAL: Internet based CBT for body dysmorphic disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion)
Status: UNKNOWN
Conditions: Hematologic Cancer|Relapse Leukemia|Relapsed Adult ALL|Relapsed Adult AML|Relapsed CLL|Relapsed Non Hodgkin Lymphoma|Relapsed Hodgkin's Lymphoma|Relapsed Myelodysplastic Syndromes|Relapsed Multiple Myeloma
Interventions: BIOLOGICAL: GLIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture
Status: RECRUITING
Conditions: Pain, Postoperative|Fracture, Ankle|Pilon Fracture of Tibia|Foot Fracture
Interventions: DEVICE: Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Baerveldt Versus ClearPath Comparison Study
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Baerveldt 350 implant|DEVICE: Ahmed ClearPath 350 implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Differences of Oocyte Maturation, Granulosa Cell Apoptosis Index Between Electroacupuncture And Sham Groups IVF
Status: COMPLETED
Conditions: Acupuncture|in Vitro Fertilization|BCL2 Gene mRNA Overexpression|Oocyte Maturation
Interventions: PROCEDURE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Hypertension in the Early Postpartum: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Pregnancy-Induced Hypertension in Postpartum|Postpartum Pre-Eclampsia|Hypertension
Interventions: DRUG: Methyldopa 250 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Hepatitis A Virus, Pharmacokinetics, and Safety of Immune Globulin (Human)
Status: COMPLETED
Conditions: Anti-Hepatitis A Antibody Levels in Heathy Subjects
Interventions: BIOLOGICAL: Immune Globulin (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Status: RECRUITING
Conditions: Lymphoproliferative Disorders|Autoimmune Lymphoproliferative|Primary T-cell Immunodeficiency Disorders|Immune System Diseases|Common Variable Immunodeficiency
Interventions: DRUG: Immunosuppression Only Conditioning|DRUG: Reduced Intensity Conditioning|DRUG: GVHD Prophylaxis|PROCEDURE: Allogeneic HSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Over-the-counter Dry Mouth Remedies After Radiation
Status: COMPLETED
Conditions: Xerostomia
Interventions: OTHER: sugar-free chewing gum|OTHER: chewing gum|OTHER: mouth rinse|OTHER: mouth rinse|DRUG: mouth spray|DRUG: mouth spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Primary PCI in Patients With ST-elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization
Status: ACTIVE_NOT_RECRUITING
Conditions: ST-elevation Myocardial Infarction|Multi Vessel Disease
Interventions: PROCEDURE: Percutaneous coronary intervention|PROCEDURE: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis
Status: COMPLETED
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis|Pain Crisis
Interventions: DRUG: GMI-1070|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: 1: Naproxen|DRUG: 2: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar Radiculopathy
Status: COMPLETED
Conditions: Piriformis Syndrome|Lumbar Radiculopathy
Interventions: DIAGNOSTIC_TEST: Ultrasound guided piriformis muscle lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diffusion MRI in Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Myocardial Infarction|Left Ventricular Hypertrophy
Interventions: DEVICE: Diffusion Tensor MRI (DTI)|DRUG: Gadolinium DOTA Meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity of 2 Versus 3 Doses of Combined Hepatitis B Vaccines in 2-18 Months Old Children
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Infanrix-hexa, Twinrix-Junior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN)
Status: RECRUITING
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: DRUG: Durvalumab|DRUG: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRCT: Ligament Reconstruction & Tendon Interposition With a Joint Spacer for Trapeziometacarpal OA
Status: TERMINATED
Conditions: Joint Disease
Interventions: PROCEDURE: LRTI|PROCEDURE: Ascension PyroDisk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Docetaxel and Cisplatin Plus Chemoradiotherapy Followed By Surgery in Treating Patients With Locally Advanced, Resectable Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Cisplatin and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Recombinant Modified Vaccinia Virus Ankara (MVA) Virus to Treat HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MVA-mBN32|BIOLOGICAL: MVA-mBN32
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Do Acid Sensing Ion Channels Contribute to Heartburn?
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Heartburn
Interventions: DRUG: Amiloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal BoNT-A Treatment in Erythematotelangiectatic Rosacea
Status: COMPLETED
Conditions: Erythematotelangiectatic Rosacea
Interventions: DRUG: Botulinum toxin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dual Task on Postural Control in Children Diagnosed With Epilepsy
Status: RECRUITING
Conditions: Epilepsy|Cognitive Function 1, Social|Balance; Distorted|Children
Interventions: OTHER: Evaluation of postural control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: SPI-1005 in Adults Receiving Cochlear Implant
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss|Cochlear Trauma
Interventions: DRUG: Ebselen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: CD07805/47 gel 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shoulder Brace on Muscle Activation and Scapular Kinematics in Patients With Shoulder Impingement Syndrome and Rounded Shoulder Posture
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Shoulder brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Avocado Intake on the Nutritional Status of Families
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: High-intake avocados|OTHER: Low-intake avocados|BEHAVIORAL: Diet tips|BEHAVIORAL: Avocado consumption advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Aliskiren and Amlodipine on the Renin-Angiotensin System (RAS) and Lipid/Carbohydrate Metabolism in Obese Patients With Hypertension
Status: TERMINATED
Conditions: Hypertension|Abdominal Obesity
Interventions: DRUG: Aliskiren|DRUG: Amlodipine|DRUG: Placebo of Aliskiren|DRUG: Placebo of amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One Session Vs Staged Management of Calcular Obstructive Jaundice
Status: RECRUITING
Conditions: Calcular Obstructive Jaundice|Gall Bladder Disease
Interventions: PROCEDURE: staged managment|PROCEDURE: one session ERCP then LC|PROCEDURE: one session LC then ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Study of a New Tranexamic Acid Dosing Schedule for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: tranexamic acid|DRUG: tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Technical Feasibility of a Ultrasuperparamagnetic Nanoparticle Iron Oxide (USPIO)-Enhanced Magnetic Resonance Lymph Node Imaging
Status: COMPLETED
Conditions: Cancer of Lymph Node
Interventions: DRUG: Feraheme|PROCEDURE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alpha-Linolenic Acid and Inflammatory Markers
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Flaxseed oil-Olive oil|DIETARY_SUPPLEMENT: Olive oil-olive oil|DIETARY_SUPPLEMENT: Flaxseed oil-sunflower oil|DIETARY_SUPPLEMENT: Olive oil-sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: DRUG: 18F fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topiramate and Schizophrenia: Effects on Weight and Psychopathology
Status: RECRUITING
Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: DRUG: Topiramate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Induction and Maintenance Immunosuppression in Kidney Transplantation
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DRUG: rabbit anti-thymocyte globulin - single dose|DRUG: mycophenolate mofetil|DRUG: rabbit anti-thymocyte globulin - 4 doses|DRUG: sirolimus|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return of Continence Following Robot-Assisted Radical Prostatectomy With or Without a Urethrovesical Sling
Status: COMPLETED
Conditions: Urinary Incontinence|Prostate Cancer
Interventions: PROCEDURE: Prostatectomy|DEVICE: Surgisis Male Sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pain During Hysterosalpingography With The Use Of Balloon Catheter Versus Metal Cannula
Status: COMPLETED
Conditions: Pain During Hysterosalpingography
Interventions: DEVICE: Balloon catheter|DEVICE: metal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity.
Status: COMPLETED
Conditions: Glucose Metabolism Disorders|Obesity|Degenerative Brain Disorder
Interventions: PROCEDURE: RYGB|DRUG: GLP-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ciclesonide Versus Placebo Administered Either as Once Daily or Twice Daily in Patients Treated Previously With an Inhaled Corticosteroid
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide (XRP1526)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Desloratadine (MK-4117) in Japanese Participants With Perennial Allergic Rhinitis (MK-4117-200)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Desloratadine 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Study of MP-513 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: teneligliptin|DRUG: glinide|DRUG: biguanide|DRUG: alpha-glucosidase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 1
Status: COMPLETED
Conditions: Myopia|Hyperopia|Contact Lens Comfort
Interventions: DEVICE: Opti-Free® PureMoist® MPDS|DEVICE: Biotrue™ MPS|DEVICE: Habitual contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Insulin and Standard Management in Hypertriglyceridemic Acute Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Hypertriglyceridemia|Acute Pancreatitis
Interventions: BIOLOGICAL: insulin|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clear Care® Plus vs. PeroxiClear™
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Clear Care Plus contact lens solution|DEVICE: PeroxiClear contact lens solution|DEVICE: Silicone hydrogel contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Irbesartan Effects on Endothelial Dysfunction in Hypertensive Type II Diabetic Patients Comparing Atenolol
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus Type 2
Interventions: DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Design and Evaluation the Effects of Kinect-based Computer Games for U/E Training in Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Kinect|BEHAVIORAL: Traditional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Blades Used for Scheduled Orotracheal Intubation on Postoperative Sore Throat
Status: COMPLETED
Conditions: Tracheal Intubation Morbidity|Sore Throat
Interventions: DEVICE: metal reusable blades MacIntosh|DEVICE: Single use plastic blades HEINE XP®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Same-day Cervical Preparation With Misoprostol Before Hysteroscopy
Status: UNKNOWN
Conditions: Cervical Preparation Prior to Hysteroscopy
Interventions: DRUG: Misoprostol (Cytotec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study of a Molecular Karyotype Using a Very High-throughput Sequencing Approach, the "Massive Parallel Sequencing" on Circulating Tumor DNA
Status: UNKNOWN
Conditions: Breast Cancer|Colo-rectal Cancer
Interventions: PROCEDURE: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inulin Supplementation During Sanative Therapy to Further Improve Periodontal Healing
Status: WITHDRAWN
Conditions: Periodontitis|Periodontal Diseases|Periodontal Pocket
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of Oral OPRX-106 (TNFR-Fc Fusion Protein) in Healthy Volunteers
Status: COMPLETED
Conditions: Human Volunteer
Interventions: DRUG: OPRX-106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males.
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: TAKC-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alvocidib in Patients With Previously Treated Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia Arising From Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic
Interventions: DRUG: alvocidib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Responsiveness as a Measure of Clinical Effectiveness During Neuromonitored Spine Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Intervertebral Disc Degeneration|Intervertebral Disc Displacement|Spinal Curvatures|Spinal Stenosis|Spondylitis|Spondylosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of VB-201 in Patients With COVID-19
Status: COMPLETED
Conditions: Severe COVID-19
Interventions: DRUG: VB-201 + Standard of care|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low-carbohydrate, High-protein Energy-restricted Diet on Weight and Body Composition Using DXA
Status: COMPLETED
Conditions: Weight Loss|Body Composition
Interventions: OTHER: High Protein Diet Group|OTHER: No High Protein Diet Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment by IN Ketamine to IV Morphine in Acute Pain
Status: UNKNOWN
Conditions: Acute Traumatic Pain
Interventions: DRUG: Morphine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: M5 vs. M6 Comparison Study With a Sub Study Into the Dielectric Constant of Aspirated Cyst Fluid
Status: COMPLETED
Conditions: Breast Cyst|Breast Cancer Female
Interventions: DEVICE: MARIA scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Botulinumtoxin A Treatment in Epidermolysis Bullosa Simplex and Pachyonychia Congenita
Status: UNKNOWN
Conditions: Epidermolysis Bullosa Simplex
Interventions: DRUG: Dysport® (Botulinumtoxin A (Btx A))|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine How Consumption of Dairy Fat as Cheese Influences Inflammation-Phase 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Obesity
Interventions: OTHER: Cheddar cheese|OTHER: Vegan cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Efficacy of Subcutaneous Isatuximab in Adults With Warm Autoimmune Hemolytic Anemia (wAIHA)
Status: TERMINATED
Conditions: Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions: DRUG: Isatuximab SAR650984
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
Status: WITHDRAWN
Conditions: Essential Arterial Hypertension
Interventions: DRUG: Candesartan + Chlorthalidone (8mg+12,5mg)|DRUG: Candesartan + Chlorthalidone (8 mg + 25 mg)|DRUG: losartan+hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using A Gelatin-Based Model In USG-Guided Jugular Venous Catheter Placement Training
Status: COMPLETED
Conditions: Central Venous Catheters|Vascular Access Devices|Education|Simulation Training|Ultrasonography, Interventional
Interventions: OTHER: Lecture|OTHER: Demo Video|OTHER: UltrasoundImaging|OTHER: ModelTraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interest in "Combo" (a Combination of Dietary Supplements Including Probiotics) in NASH Improvement
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Treatment with Combo|OTHER: Treatment with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization Versus Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Liver Neoplasms
Interventions: RADIATION: Radiation therapy|DEVICE: chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGN-EGFRd2 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Colorectal Neoplasms|Carcinoma, Non-Small-Cell Lung|Squamous Cell Carcinoma of the Head and Neck|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: SGN-EGFRd2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MARCH Central Nervous System Substudy
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Arm 1 TNucleotide Analogue Reverse Transcriptase Inhibitors and Boosted Protease Inhibitors|DRUG: Arm 2 Maraviroc and Protease Inhibitors|DRUG: Arm 3 Maraviroc and Nucleotide Analogue Reverse Transcriptase Inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Dexamethasone Doses on Persistent Postmastectomy Pain
Status: UNKNOWN
Conditions: Mastectomy, Modified Radical
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronidase in Intra-articular Steroid Injection Treating the Adhesive Capsulitis for Shoulder
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DRUG: Triamcinolone Acetonide 40mg/mL|DRUG: Hyaluronidase Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Guselkumab and Ustekinumab Following a Single Intravenous or Subcutaneous Administration in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Guselkumab (SC): Dose 1|DRUG: Guselkumab (SC): Dose 2|DRUG: Guselkumab (IV): Dose 1|DRUG: Guselkumab (IV): Dose 2|DRUG: Ustekinumab 6 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of CM310 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CM310|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Thoracic Aortic Aneurysm Among a Cohort of Patients With a Degenerative Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium
Status: ACTIVE_NOT_RECRUITING
Conditions: Barrett's Esophagus|Esophageal Squamous Dysplasia|Esophageal Cancer
Interventions: DEVICE: CryoBalloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Risk of Falls Index for Patients With Neuromuscular Disorders
Status: RECRUITING
Conditions: Inclusion Body Myositis|Myotonic Dystrophy|Facioscapulohumeral Muscular Dystrophies|Myasthenia Gravis|The Falls Efficacy Scale International|The Morse Fall Scale
Interventions: DIAGNOSTIC_TEST: The risk of falls
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|BIOLOGICAL: Nivolumab (Opdivo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pain and Autonomic Dysreflexia in Spinal Cord Injury With Deep Brain Stimulation
Status: COMPLETED
Conditions: Pain|Autonomic Dysreflexia
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Chronic Fatigue in Multiple Sclerosis: MS Copilot Boost Solution Compared to Standard Care
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Fatigue Syndrome, Chronic
Interventions: DEVICE: MS Boost|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IMC001 for Clinical Research on Advanced Digestive System Malignancies
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma|Advanced Colorectal Cancer|Advanced Gastric Cancer|Advanced Pancreatic Cancer
Interventions: DRUG: EPCAM CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Probiotics Improve Recovery From Acute Constipation in Kids?
Status: RECRUITING
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Culturelle Probiotic + Fiber|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia
Status: RECRUITING
Conditions: Neonatal Encephalopathy
Interventions: DRUG: Sildenafil|DRUG: Ora-Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intramedullary Nailing of the Femur:Trochanteric vs Piriformis Starting Portals
Status: COMPLETED
Conditions: Femur Fracture
Interventions: DEVICE: Antegrade Intramedullary Nail|DEVICE: Trigen Trochanteric Femoral Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT