pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Transforaminal Epidural Platelet Rich Plasma Versus Epidural Steroid Injection for Lumbosacral Radicular Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Dexamethasone 4mg|PROCEDURE: epidural platelet rich plasma injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of "VIRACIDE" IN THE MANAGEMENT OF CORONA VIRUS DISEASE 2019 (COVID-19)
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Investigational Product - ViraCide|OTHER: Placebo - Starch Powder Soft gels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nerve Decompression for Ulcer Recurrence Avoidance (DURA)
Status: UNKNOWN
Conditions: Diabetic Ulcer of Plantar Aspect of Left Foot|Diabetic Ulcer of Plantar Aspect of Right Foot|Diabetic Polyneuropathy
Interventions: PROCEDURE: nerve decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus
Status: RECRUITING
Conditions: Music Therapy|Preterm Premature Rupture of Membrane (PPROM)
Interventions: BEHAVIORAL: Music Therapy Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PMS Study of Silver I Alginate Non-Woven Dressing (Hydro-Alginate)
Status: RECRUITING
Conditions: Wound
Interventions: DEVICE: Silver I Alginate Non-Woven Dressing (Hydro-Alginate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH)
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: Clazosentan 1 mg/h|DRUG: Clazosentan 5 mg/h|DRUG: Clazosentan 15 mg/h|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Obesity Hypoventilation Syndrome|Metabolic Alkalosis
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms Underlying Hypoxic, Heat and Cross-tolerance Adaptation in Women
Status: NOT_YET_RECRUITING
Conditions: Heat Exposure|Exercise Training
Interventions: OTHER: Heat acclimation and exercise training|OTHER: Thermo-neutral exercise training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Mepolizumab in Polish Patients With Severe Eosinophilic Asthma
Status: UNKNOWN
Conditions: Asthma; Eosinophilic
Interventions: BIOLOGICAL: Mepolizumab given SC 100mg every 4 weeks between Dec 2017 and Dec 2019
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis A
Interventions: PROCEDURE: Blood sampling|BIOLOGICAL: Additional challenge dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Manual Therapy Techniques on Cervical Spine and Psychological Interaction
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Cervical manipulation|OTHER: Cervical lateral glide|OTHER: Cervical mobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Male Provider Phone Calls to Increase Men's Clinic Linkage After HIVST
Status: ENROLLING_BY_INVITATION
Conditions: HIV|Linkage to Care|PMTCT|PrEP|ART Adherence
Interventions: DIAGNOSTIC_TEST: POC viral load testing|OTHER: Wellness visit services for male partners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Phentermine and B12 on Weight Loss Among Obese Patients
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: DRUG: Phentermine and B12|DRUG: Phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Placebo|DRUG: Milnacipran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease|Cerebrovascular Disease|Peripheral Vascular Disease
Interventions: DRUG: Rifalazil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Avastin/FOLFIRI in Combination With Curcumin in Colorectal Cancer Patients With Unresectable Metastasis
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Avastin/FOLFIRI|DIETARY_SUPPLEMENT: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 88% sucrose po solution|DRUG: placebo po
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Aflibercept|DRUG: Placebo (for aflibercept)|DRUG: Docetaxel|DRUG: Prednisone or Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vactosertib in Combination w/ Pomalidomide in Relapsed or Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Vactosertib|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupressure Wristbands or Standard Care in Controlling Nausea Caused by Chemotherapy
Status: COMPLETED
Conditions: Anxiety Disorder|Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: acupressure therapy|PROCEDURE: quality-of-life assessment|PROCEDURE: sham intervention|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Mesh Fixation Wit Cyanoacrylate vs Suture in Inguinal Hernia Surgery
Status: COMPLETED
Conditions: Chronic Pain
Interventions: PROCEDURE: Inguinal mesh hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: 6 Gy/ fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Islamic Psychospiritual-Acceptance and Commitment-based Prevention Program for At-risk Young Adults in the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Psychological Distress
Interventions: BEHAVIORAL: 5-week prevention program|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Golimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic Remission
Status: UNKNOWN
Conditions: Colitis, Ulcerative
Interventions: DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocolised Early De-Resuscitation in Septic Shock (REDUCE)
Status: RECRUITING
Conditions: Septic Shock
Interventions: OTHER: Fluid management according to the REDUCE Fluid Protocol|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1, Single-arm, Open-label, Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Liver Carcinoma|Hepatic Cell Carcinoma
Interventions: BIOLOGICAL: CAR-GPC3 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Individual, Dyadic, and Collaborative Plans on Physical Activity in Partner-Partner Dyads
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Individual Planning|BEHAVIORAL: Dyadic Planning|BEHAVIORAL: Collaborative Planning|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Bronchial Carcinoma|Hodgkin Disease|Non-Hodgkin Lymphoma|Weight Loss
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity Assessment of Subjects Receiving Rabies Post-exposure Prophylaxis in Cambodia
Status: COMPLETED
Conditions: Rabies Post-exposure Prophylaxis
Interventions: BIOLOGICAL: Intramuscular (IM) rabies post-exposure prophylaxis|BIOLOGICAL: Intradermal (ID) rabies post-exposure prophylaxis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Filter Ventilation and Ventilation Information on Product Use Behaviors in Cigarette Smokers
Status: COMPLETED
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: OTHER: Cigarette packaging|OTHER: Data capture|OTHER: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia
Status: TERMINATED
Conditions: Minimal Residual Disease|Leukemia, Lymphoblastic, Acute|Leukemia, Myelogenous, Acute
Interventions: DRUG: Clofarabine|DRUG: Cytarabine intravenous|DRUG: Methotrexate|DRUG: Intrathecal (IT) Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging
Status: RECRUITING
Conditions: Healthy|Carotid Artery Diseases
Interventions: DEVICE: Ultrasound imaging|DEVICE: Magnetic Resonance Imaging (MRI)|OTHER: Neurocognitive testing|DEVICE: Transcranial Doppler (TCD)|DEVICE: Pulse Wave Doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of SSP-004184 (SPD602) on the Pharmacokinetics of Simvastatin in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Simvastatin|DRUG: SSP-004184SS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)
Status: COMPLETED
Conditions: Compensated Advanced Chronic Liver Disease
Interventions: DIAGNOSTIC_TEST: Esophagogasrtoduodendoscopy|DIAGNOSTIC_TEST: Hepatic venous pressure gradient
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NOGA Angiogenesis Revascularization Therapy: Evaluation by RadioNuclide Imaging - The Northern Trial
Status: UNKNOWN
Conditions: Myocardial Ischemia
Interventions: PROCEDURE: intramyocardial delivery of either VEGF165 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of a GSK Influenza Vaccine Candidate in Adults.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' quadrivalent influenza vaccine|BIOLOGICAL: GSK Biologicals' trivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders
Status: COMPLETED
Conditions: Substance-Related Disorders|Depressive Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: Outpatient MST/OPTION-A|BEHAVIORAL: Usual Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: modafinil|DRUG: methylphenidate|DRUG: lorazepam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: B-type NAtriuretic Peptide In Critically Ill : A Multicentric Diagnostic Study (B-rAPID)
Status: UNKNOWN
Conditions: Heart Failure|Congestive Cardiac Failure|Dyspnoea
Interventions: OTHER: Patients who will receive the BNP test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Fecal Microbiome in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: PRIM-DJ2727|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic NSCLC - Non-Small Cell Lung Cancer|Locally Advanced NSCLC - Non-Small Cell Lung Cancer
Interventions: DRUG: inupadenant|DRUG: Placebo|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Tucidinostat|DRUG: Sintilimab|DRUG: Bevacizumab|DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofunctional Therapy With an Application in Severe Apnea/Hypopnea Sleep Obstructive Syndrome (MTASSAOS)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea-hypopnea Syndrome
Interventions: DEVICE: The intervention consists of myofunctional therapy (MT) using the AirwayGym app.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator
Status: COMPLETED
Conditions: Tachycardia|Diabetes Mellitus|Cardiovascular Disease
Interventions: DEVICE: Subcutaneous Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Racial Differences in Vagal Control of Glucose Homeostasis
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Galantamine|DRUG: Placebo Oral Capsule|DRUG: Intralipid|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation in the Term Newborns Delivered by Caesarean Section
Status: COMPLETED
Conditions: Microbiota, Cesarean Section, Probiotics, Dysbiosis
Interventions: DIETARY_SUPPLEMENT: containing Bifidobacterium breve PB04, Lactobacillus rhamnosus KL53A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic
Status: ENROLLING_BY_INVITATION
Conditions: Suicide, Attempted|Suicidal Ideation
Interventions: DEVICE: OTX-202|DEVICE: OTX-000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Ankle Therapy on Fear of Falls, Range of Motion, and Functionality and Stability in Geriatric Patients
Status: COMPLETED
Conditions: Old Age; Atrophy
Interventions: OTHER: Experimental|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hemp-derived, Full Spectrum Cannabigerol (CBG) in Adults
Status: COMPLETED
Conditions: Health, Subjective|Inflammatory Response|Adverse Effect|Side Effect
Interventions: OTHER: Cannabigerol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)
Status: COMPLETED
Conditions: Anorexia|Cachexia|Fatigue|Lung Cancer
Interventions: BIOLOGICAL: infliximab|DRUG: docetaxel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Living Alone is Predictive of Non-home Discharge Following Elective Total Hip Arthroplasty: a Matched-pairs Cohort Analysis
Status: COMPLETED
Conditions: Arthropathy of Hip|Perioperative/Postoperative Complications
Interventions: BEHAVIORAL: home support, hiving alone|BEHAVIORAL: home support, living with others
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Pembrolizumab (MK-3475) + Pegylated Interferon Alfa-2b and Pembrolizumab+ Ipilimumab in Participants With Advanced Melanoma or Renal Cell Carcinoma (MK-3475-029/KEYNOTE-29)
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: PegIFN-2b|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: cyclophosphamide|BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclosporine|PROCEDURE: allogeneic bone marrow transplantation|DRUG: methotrexate|GENETIC: DNA analysis|OTHER: flow cytometry|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of BIBR 277 Tablet (Mannitol Based) Compared With Capsule Formulation in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 277 tablet|DRUG: BIBR 277 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Neuromodulation for Anhedonic Depression
Status: RECRUITING
Conditions: MDD|Anhedonia
Interventions: DEVICE: Individualized Accelerated Intermittent Theta Burst Stimulation (Ind-aiTBS)|DEVICE: Standard Accelerated Intermittent Theta Burst Stimulation (Std-aiTBS)|DEVICE: Sham Accelerated Intermittent Theta Burst Stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: REAL3 Trial of Efficacy of EOX With/Without Panitumumab in Previously Untreated Adv OG Cancer
Status: TERMINATED
Conditions: Oesophago-gastric Cancer
Interventions: DRUG: epirubicin, oxaliplatin, capecitabine (EOX)|DRUG: EOX + panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Post-vaccination Immune Response to COVID-19 in the New Caledonian Population
Status: COMPLETED
Conditions: SARS-CoV-2 Acute Respiratory Disease
Interventions: OTHER: Blood sample collection|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasonography Guided Pleural Biopsy Versus Computed Tomography Guided Pleural Biopsy
Status: COMPLETED
Conditions: Pleural Diseases
Interventions: PROCEDURE: CT-Guided pleural needle biopsy with Abrams' needle|PROCEDURE: Ultrasonography guided cutting pleural needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Timing of Operation in Children With a Prenatal Diagnosis of Choledochal Cyst
Status: NOT_YET_RECRUITING
Conditions: Choledochal Cyst
Interventions: PROCEDURE: laparoscopic-assisted CDC excision and hepaticojejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F]Fluciclovine in Post-treatment Glioblastoma ( Axumin )
Status: COMPLETED
Conditions: Glioma Glioblastoma Multiforme
Interventions: DRUG: Axumin, Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Different Screening Score for Hypoxemic OSA (Obstructive Sleep Apnea) With the Results of a Polysomnography (PSG)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: OTHER: All patients incoming in the sleep study centre for a PSG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiac Output Optimization on Postoperative Complications in Major Hepatic Surgery
Status: RECRUITING
Conditions: Primary or Metastatic Hepatic Adenocarcinoma
Interventions: BEHAVIORAL: Optimization of cardiac flow by base water-electrolyte supply|BEHAVIORAL: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Cardiovascular Stiffening With Aging and Hypertensive Heart Disease
Status: COMPLETED
Conditions: Lv Hypertrophy|Heart Failure, Diastolic|Stiffness, Vascular
Interventions: BEHAVIORAL: High intensity exercise|BEHAVIORAL: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Testosterone Replacement in Patients With Low Risk Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Androderm® 2.5mg|DRUG: Androderm® 5.0mg|DRUG: Androderm® 7.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronx Transthyretin Amyloid Cardiomyopathy Database
Status: ACTIVE_NOT_RECRUITING
Conditions: Transthyretin Cardiac Amyloidosis|Transthyretin Amyloid Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: 99mTc-pyrophosphate Single Photon Emission Computed Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LEO 124249 Ointment in the Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: LEO 124249|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assesment of Gingival Crevicular Fluid and Serum ErbB4/Neuregulin-4 Levels in Periodontal Disease and Health
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: non surgical periodontal treatment|OTHER: Gingival crevicular fluid and serum collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Pazopanib in Patients With Solitary Fibrous Tumor and Extraskeletal Myxoid Chondrosarcoma
Status: COMPLETED
Conditions: Solitary Fibrous Tumor|Extraskeletal Myxoid Chondrosarcoma
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy of Three Dry Mouth Relief Products Versus Water
Status: COMPLETED
Conditions: Xerostomia
Interventions: DEVICE: Experimental Oralbalance Moisturizing Gel|DEVICE: Biotene Original Oral Rinse|DEVICE: Biotene Moisturizing Mouth Spray|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Oro-esophageal Tube Feeding in Traumatic Brain Injury Patients
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Rehabilitation therapy|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Utility of the Apoptosis Imaging Biomarker 18F]ML10 in Patients With Non-Hodgkin's Lymphoma(NHL)
Status: TERMINATED
Conditions: Cancer
Interventions: RADIATION: ML10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Upper Limb Tremor Reduction in Essential Tremor Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Tremor
Interventions: DEVICE: Encora Therapeutics Tremor Reduction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenosine Contrast CorrELations in Evaluating RevAscularizaTION
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: Iopamidol|DRUG: adenosine|DEVICE: Navvus® Catheter|DEVICE: CVi® Contrast Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 99mTc-MY6349 SPECT/CT Imaging in Trop2-positive Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: 99mTc-MY6349 SPECT/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM)
Status: COMPLETED
Conditions: HTLV-I Infection|Spinal Cord Disease|Tropical Spastic Paraparesis
Interventions: DRUG: Recombinant human interferon beta-1a
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: COVID-19: Herd Immunity Study in the Czech Republic
Status: COMPLETED
Conditions: COVID|SARS-CoV 2
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 diagnostic rapid test|DIAGNOSTIC_TEST: Quantitative analysis of SARS-CoV-2 antibodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial
Status: RECRUITING
Conditions: Heart Failure|Cardiotoxicity|Cancer
Interventions: BEHAVIORAL: Cardio-oncology Rehabilitation (CORE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Acute Pericarditis With Anakinra
Status: TERMINATED
Conditions: Acute Pericarditis
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
Status: COMPLETED
Conditions: Elective Colonoscopy
Interventions: DRUG: Phase II: NTC015 low dose|DRUG: Phase II: NTC015 medium dose|DRUG: Phase II: NTC015 high dose|DRUG: Phase III: NTC015 selected dose|DRUG: Phase III: Polyethylene glycol plus ascorbate solution (2L PEG ASC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PeRioperative Study of Exercise Training in Patients With Operable Cancer of the Gastroesophageal Junction
Status: COMPLETED
Conditions: Gastro-esophageal Cancer
Interventions: BEHAVIORAL: Aerobic and Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of the ChAdox1 n CoV-19 Vaccine With 12-dose Vial
Status: COMPLETED
Conditions: Covid19|Vaccine|Immunogenicity
Interventions: BIOLOGICAL: Immunogenicity after first dose of participants who received first dose of ChAdox-1 n COV-19 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-FAPI PET/CT in Pancreatic Ductal Carcinoma
Status: UNKNOWN
Conditions: PDAC
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI Positron Emission Tomography-Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning
Status: RECRUITING
Conditions: Sarcoma, Ewing|Chondrosarcoma|Osteosarcoma|Fibrous Histiocytoma|Fibrosarcoma
Interventions: DEVICE: 3D Printed Anatomic Model|DIAGNOSTIC_TEST: CT/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs
Status: RECRUITING
Conditions: Myeloproliferative Neoplasms (MPNs)
Interventions: DIAGNOSTIC_TEST: Reverse transcription-quantitative polymerase chain reaction (RT-qPCR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Compliance and Pharmacokinetics of Estetrol Monohydrate/Drospirenone 15/3 mg in Post-menarchal Female Adolescents
Status: COMPLETED
Conditions: Safety
Interventions: DRUG: E4/DRSP 15/3 mg combined tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ION251 Administered to Patients With Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: ION251
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%
Status: UNKNOWN
Conditions: The Focus of the Study is to Assess the Effectiveness of Topical Ivermectin on Eliminating Eyelash Sleeves
Interventions: DRUG: Ivermectin cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Dynamic Taping on Upper Body Posture.
Status: COMPLETED
Conditions: Dynamic Tape|Postural; Defect
Interventions: OTHER: Dynamic tape on experimental group|OTHER: Sham tape on placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Posterior Versus Lateral Laparoscopic Mesh Rectopexy for the Management of Complete Rectal Prolapse
Status: RECRUITING
Conditions: Posterior Laparoscopic|Lateral Laparoscopic|Rectopexy|Complete Rectal Prolapse
Interventions: PROCEDURE: Laproscopic posterior mesh rectopexy (Wells or LPMR)|PROCEDURE: Laparoscopic lateral mesh rectopexy (Orr-Loygue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Left-sided Hepatectomy Trial
Status: UNKNOWN
Conditions: Neoplasm, Liver
Interventions: PROCEDURE: Open left-sided hepatectomy|PROCEDURE: Laparoscopic left-sided hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: neoadjuvant chemotherapy plus total mesorectal excision|PROCEDURE: total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate the Safety and Efficacy of Lenalidomide With MOR00208 in Patients With R-R DLBCL
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GSK3915393|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: breathing helium-hyperoxia|OTHER: breathing supplemental oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Intervention for Individuals With Lower Extremity Amputation
Status: COMPLETED
Conditions: Lower Extremity Amputation
Interventions: BEHAVIORAL: Coached group|BEHAVIORAL: Self-directed control group|OTHER: Screened only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Pilot Test of a Postnatal mHealth Intervention - Phase 2
Status: COMPLETED
Conditions: Health Attitude|Knowledge, Attitudes, Practice|Post Partum Depression|Acceptability of Health Care
Interventions: BEHAVIORAL: MESSSSAGE - live|BEHAVIORAL: MESSSSAGE - asynchronous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of FTX-6058
Status: COMPLETED
Conditions: Healthy Adult Subjects|Sickle Cell Disease
Interventions: DRUG: FTX-6058/placebo oral capsule(s)|DRUG: FTX-6058/placebo oral capsule(s)|DRUG: FTX-6058 - Two Dosing Periods|DRUG: FTX-6058 / Midazolam Syrup|DRUG: FTX-6058/placebo oral capsule(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical-functional Effects of Bariatric Surgery on the Musculoskeletal System in Relation to Bone Turnover.
Status: NOT_YET_RECRUITING
Conditions: Bariatric Surgery Candidate
Interventions: OTHER: 50 adult patients suffering from severe or morbid obesity, male and female, candidates for bariatric surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate the Use of Ultrasound in the Diagnosis of Hemophilic Joint Disease
Status: COMPLETED
Conditions: Inherited Bleeding Disorders
Interventions: PROCEDURE: Power Doppler Sonography|PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach
Status: TERMINATED
Conditions: Atrial Fibrillation|Persistent or Longstanding Persistent Atrial Fibrillation
Interventions: DEVICE: AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19
Status: UNKNOWN
Conditions: Covid19|SARS (Severe Acute Respiratory Syndrome)|SARS-CoV Infection|SARS-CoV-2
Interventions: BIOLOGICAL: Biological: oral polio vaccine|BIOLOGICAL: Comparable Placebo|DRUG: NA-831|DRUG: Comparable Placebo of drug|COMBINATION_PRODUCT: Combination of oral polio vaccine and NA-831|COMBINATION_PRODUCT: Comparable Placebo of Oral Polio Vaccine and Placebo of drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitigating Infectious Morbidity and Growth Deficits in HIV Exposed Uninfected infanTs With Human Milk Oligosaccharides
Status: RECRUITING
Conditions: HIV|Infant Morbidity|Breast Feeding
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Lidocaine for Scleroderma
Status: COMPLETED
Conditions: Scleroderma
Interventions: DRUG: Lidocaine 2% without vessel constrictor|OTHER: Placebo - physiological solution 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A One-year, Open-label Study to Assess the Safety and Effectiveness of Extended Release Tramadol HCl in the Treatment of Chronic, Non-malignant Pain.
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: tramadol ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Oral Senicapoc Administration on Exercise-induced Asthma
Status: COMPLETED
Conditions: Exercise Induced Asthma
Interventions: DRUG: senicapoc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome?
Status: COMPLETED
Conditions: Multi Organ Failure
Interventions: PROCEDURE: haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Clinical and Functional Results After Operative Correction of Lesser Toe Deformities
Status: COMPLETED
Conditions: Plantar Plate Tear|Metatarsalgia|Lesser Metatarsophalangeal Joint Instability|Hammer Toe|Surgery|Plantar Plate Repair
Interventions: PROCEDURE: plantar plate repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET
Status: COMPLETED
Conditions: Opiate Dependence|Cocaine Dependence
Interventions: DIAGNOSTIC_TEST: 11UCB-J PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Expanding Reach of Evidence-based Psychotherapy for Veterans With Co-occurring Anxiety and Substance Use Disorders.
Status: COMPLETED
Conditions: Anxiety Disorders|Substance Use Disorders
Interventions: BEHAVIORAL: VA Coordinated Anxiety Learning and Management- Substance Use Version|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insertion Protocol of Convergent Transmucosal Design Implants
Status: RECRUITING
Conditions: Implant Site Reaction
Interventions: PROCEDURE: Equi-crestal Implant placement|PROCEDURE: Sub-crestal Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Efficacy of High-intensity Laser Therapy in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: High-intensity laser therapy (HILT)|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Motivation Coaches, Social Media-based Support Group, and Behavior Change Strategies to Decrease Prolonged Sitting and Increase Moderate Exercise Snacks
Status: ACTIVE_NOT_RECRUITING
Conditions: Sedentary Behavior|Physical Inactivity
Interventions: BEHAVIORAL: MOV'D (Move Often eVery Day)|BEHAVIORAL: Fitbit Self-Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Near-infrared Fluorescence With Indocyanine Green for Identification of Sentinels and Parathyroids During Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Cancer|Thyroid Carcinoma, Papillary|Thyroid Metastases|Thyroid Neoplasms|Sentinel Lymph Node|Lymph Node Metastases
Interventions: PROCEDURE: Total thyroidectomy (TT)|PROCEDURE: Central lymph node dissection (CLND)|DIAGNOSTIC_TEST: Sentinel lymph node (SLN) bopsy|DIAGNOSTIC_TEST: Identification of parathyroid glands (PGs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Perturbation-based Balance Training on Postural Control and Cortical Modulation in Elderly With Fall Risk
Status: COMPLETED
Conditions: Old Age; Debility|Fall
Interventions: OTHER: Perturbation-based balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pandemic Influenza A (H1N1) Vaccine in Chronic and or Immunocompromised Patients, Elderly and Pregnants
Status: COMPLETED
Conditions: Immunocompromised Patients|Safety of Pandemic Influenza A (H1N1)Vaccine|Immunogenicity of Pandemic Influenza A (H1N1)Vaccine
Interventions: BIOLOGICAL: Split inactivated A/California/7/2009 (H1N1) (NYMC X-179A) VIRUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Fenofibrate on the Safety, Toleration and Efficacy Biomarkers of CP-742,033
Status: WITHDRAWN
Conditions: Obesity
Interventions: DRUG: CP-742,033|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Nudging Provider Adoption of Clinical Decision Support
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: OTHER: Pulmonary Embolism Risk Kalculator (PERK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Comparison With Clinical Impacts on Functional Capacity and Symptom Improvement According to the Rhythm Control in Patients With Heart Failure and Recent Onset Atrial Fibrillation
Status: UNKNOWN
Conditions: Heart Failure|Recent Onset Atrial Fibrillation
Interventions: PROCEDURE: Sinus Rhythm control|PROCEDURE: Pulse Rate control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT