pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: One Drop Experts Program for Type 2 Diabetes Self-Management: Impact on A1c
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: One Drop Experts Program|BEHAVIORAL: One Drop Experts Program + Apple Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Innovative Interventions for Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Nicotine Patch|OTHER: VLNC Cigarette|OTHER: VLNC Cigarette Plus Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tulobuterol Patch in Pediatric Patients Undergoing Tonsillectomy
Status: COMPLETED
Conditions: Tonsillar Hypertrophy
Interventions: DRUG: Tulobuterol Hydrochloride|DRUG: Placebo transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Wii Fit as a Low-Cost Virtual Reality System to Evaluate Balance Ability in Older Adults
Status: COMPLETED
Conditions: Falls, Accidental
Interventions: OTHER: Wii Fit Balance Games|OTHER: NeuroCom EquiTest® System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound-guided Erector Spinae Plane Block Versus Paravertebral Block for Perioperative Analgesia in Patients Undergoing Open Splenectomy
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: ultrasound guided erector spinae plane block|PROCEDURE: ultrasound guided paravertebral block|DRUG: conventional analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemia or Mixed Dyslipidemia
Status: COMPLETED
Conditions: Diabetes, Hyperlipidemia, Mixed Dyslipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Atomoxetine for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: Lamotrigine|DRUG: Divalproex (DIV) ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Length of Remission With Intensive Chemotherapy in Rapidly Responding AML Patients.
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Prescribing conventional chemotherapy while with holding allo-SCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microscopic Peritoneal Metastases After Complete Macroscopic Cytoreductive Surgery for Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: PROCEDURE: Peritoneal biopsies after complete macroscopic cytoreduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Trial of Sorafenib in Combination With Cisplatin Followed by Paclitaxel for Early Stage Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Sorafenib|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Telerehabilitation-based Exercises in Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis|Exercise|Telerehabilitation|Exercise Capacity
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Digestive System Neoplasm|Metastatic Head and Neck Carcinoma|Metastatic Kidney Carcinoma|Metastatic Malignant Neoplasm in the Spine|Metastatic Malignant Neoplasm of Unknown Primary|Metastatic Melanoma|Prostate Carcinoma Metastatic in the Bone|Sarcoma|Solid Neoplasm|Spinal Cord Compression|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Lung Non-Small Cell Cancer AJCC v7|Thyroid Gland Carcinoma
Interventions: PROCEDURE: Computed Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Radiosurgery|PROCEDURE: Thermal Ablation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|EGFR Gene Mutation|EGFR|ALK Gene Mutation|RET Gene Mutation|MET Gene Mutation|KRAS Mutation-Related Tumors|BRAF|ROS1 Gene Mutation
Interventions: OTHER: Sensus Smartwatch Application|DEVICE: RX Cap|DEVICE: Fitbit Sense|OTHER: Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindfulness-Based Stress Reduction for Metro Nashville Public School Employees
Status: COMPLETED
Conditions: Self-compassion|Burnout|Stress|Anxiety|Depression
Interventions: BEHAVIORAL: Remote Mindfulness-Based Stress Reduction Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Effectiveness of Electronic Interventions on the Standardized Prescription Benzodiazepines and Z-drugs
Status: COMPLETED
Conditions: Bcenzodiazepines, Abuse, Retrospective Study, Focus Groups, Real-world Study
Interventions: BEHAVIORAL: waiting list|BEHAVIORAL: benzodiazepines related knowledge intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Diabetes|Hyperglycemia
Interventions: DRUG: IV insulin to maintain target glucose concentration of 80-130 mg/dL|DRUG: Standard Care control - sliding scale insulin to keep glucose less than 180 mg/dL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer|Neurotoxicity|Ovarian Cancer
Interventions: DRUG: cisplatin|DRUG: dimesna|DRUG: paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of AAVrh10-h.SGSH Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)
Status: UNKNOWN
Conditions: Mucopolysaccharidosis Type IIIA
Interventions: DRUG: LYS-SAF302
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Status: RECRUITING
Conditions: Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Large Cell Lymphoma|Refractory Childhood Acute Lymphoblastic Leukemia|Refractory Childhood Hodgkin Lymphoma|Refractory Childhood Malignant Germ Cell Neoplasm|Recurrent Childhood Brain Tumor|Recurrent Childhood Brainstem Glioma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Childhood Ependymoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Gliosarcoma|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Childhood Malignant Solid Neoplasm|Recurrent Childhood Malignant Solid Neoplasm|Recurrent Childhood Malignant Neoplasm|Refractory Childhood Malignant Neoplasm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC)
Status: RECRUITING
Conditions: Advanced Gastric Carcinoma
Interventions: DRUG: Ferinject|OTHER: Conservative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of Intravenous RPX7009 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Bacterial Infections
Interventions: DRUG: RPX7009|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of VTE Prophylaxis in TBI
Status: WITHDRAWN
Conditions: TBI (Traumatic Brain Injury)|VTE (Venous Thromboembolism)
Interventions: DRUG: Enoxaparin Sodium 150 MG/ML Prefilled Syringe|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction，a Phase II Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer|Adenocarcinoma
Interventions: DRUG: Sintilimab,nab-paclitaxel and tegio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcitriol and Dexamethasone in Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Calcitriol|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors
Status: TERMINATED
Conditions: Kaposiform Hemangioendothelioma (KHE)|Kasabach-Merritt Syndrome|Tufted Angioma
Interventions: DRUG: Vincristine|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Impact of the Urine Test Cxbladder Detect+ on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.
Status: NOT_YET_RECRUITING
Conditions: Hematuria - Cause Not Known
Interventions: DIAGNOSTIC_TEST: Cxbladder Detect+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic/Pharmacokinetic and Safety Studies of SHR4640 in Subjects With Moderate Renal Insufficiency and Healthy Subjects
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: SHR4640
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Go For It: to Improve Levels of Daily Physical Activity and to Reduce the Sedentary Life Style of Adolescents With CP
Status: UNKNOWN
Conditions: Cerebral Palsy (CP)
Interventions: OTHER: Life style changing: reducing sedentary behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Medical Record Reminders and Panel Management to Improve Primary Care of Elderly Patients
Status: COMPLETED
Conditions: EMR Reminders to Improve Rates of Recommended Care
Interventions: OTHER: EMR Reminder|OTHER: EMR Reminder + Panel management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)
Status: COMPLETED
Conditions: Squamous Cell Cancer|Head and Neck Cancer
Interventions: DRUG: Temsirolimus + Weekly Paclitaxel + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)|Dilated Cardiomyopathy
Interventions: DEVICE: AccuCinch Ventricular Restoration System|DRUG: Guideline-Directed Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Atorvastatin With Tipranavir/Ritonavir and the Effect of Antacid on the Pharmacokinetics of Single-Dose Tipranavir/Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Atorvastatin|DRUG: Maalox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wet-to-dry vs Petrolatum & Non-stick Dressings After Hidradenitis Suppurativa Surgery
Status: COMPLETED
Conditions: Hidradenitis Suppurativa|Surgical Wound
Interventions: DEVICE: Wet-to-Dry Dressings|DEVICE: Petrolatum with Non-Stick Gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Negative Postprandial Effect on Endothelium After a Not-healthy Meal in Type 2 Diabetes as Affected by Training
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: 47 min moderate intensity training|BEHAVIORAL: exercise healthy volunteers|BEHAVIORAL: control; no exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory
Status: RECRUITING
Conditions: Endometriosis, Rectum|Endometriosis of Colon|Subfertility, Female
Interventions: PROCEDURE: Laparoscopic excision of endometriosis, including colorectal endometriosis|PROCEDURE: In vitro fertilisation or intracytoplasmic sperm injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Uncomplicated Malaria in Benin
Status: COMPLETED
Conditions: Uncomplicated Malaria
Interventions: DRUG: sulfadoxine-pyrimethamine|DRUG: artemether-lumefantrine|DRUG: amodiaquine-artesunate coformulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarilumab in Patients With Glucocorticoid-Dependent Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Sarilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma
Status: RECRUITING
Conditions: Low Grade Glioma
Interventions: OTHER: model-guided optimization of treatment plan|OTHER: standard treatment plan, no optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AK106-001616|DRUG: Placebo|DRUG: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neo Adjuvant Chemotherapy in Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Carboplatin and Paclitaxel|DRUG: Doxorubicin, cyclophosphamide|DRUG: Doxorubicin, cyclophosphamide, carboplatin, thiotepa, cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Self Hypnotic Relaxation As An Adjunct To Local Anesthesia During Large Core Breast Biopsy
Status: COMPLETED
Conditions: Breast Cancer|Anxiety|Pain
Interventions: BEHAVIORAL: Self-hypnotic Relaxation|BEHAVIORAL: Empathic Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Improving Outcomes and Reducing Disparities for Patients With Inflammatory Bowel Disease Through Epidemiology and Enhanced Disease Management
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Colitis
Interventions: OTHER: Enhanced Digital Care|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of an Intensive Care Diary on Post-traumatic Stress Disorder After a Resuscitated Sudden Death
Status: UNKNOWN
Conditions: Sudden Death|Sudden Cardiac Arrest
Interventions: OTHER: Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraperitoneal and System Chemotherapy Versus XELOX as First-line Chemotherapy for mCRC
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic|Chemotherapy Effect|Chemotherapeutic Toxicity
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alcohol Inhibits Drug Metabolism by Carboxylesterases
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: Placebo|DRUG: Ethanol|DRUG: Oseltamivir|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial Evaluating the Efficacy of Ultra Low Dose of Decitabine in Myelodysplastic Syndromes (MDS)
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Tolerability of Oral AZD3241 in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: AZD3241 300 mg BID|DRUG: AZD3241 600 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the CR Neuromodulation Treatment for Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: CR Neuromodulation|DEVICE: Tinnitus masking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cells for Type 1 Diabetes Mellitus (T1DM) Therapy
Status: UNKNOWN
Conditions: Treatment of Type I Diabetes Mellitus.
Interventions: BIOLOGICAL: Biological
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tear Evaporation Rate With DAILIES TOTAL1 and Biotrue ONEday
Status: COMPLETED
Conditions: Evaporative Dry Eye
Interventions: DEVICE: Nesofilcon A|DEVICE: Delefilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Brain Injuries|Transcranial Magnetic Stimulation|Magnetic Resonance Spectroscopy|Biomarkers|Depression, Anxiety
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation to Right Dorsolateral Prefrontal Cortex|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation|DEVICE: Repetitive Transcranial Magnetic Stimulation to Right Dorsomedial Prefrontal Cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Bile Duct Brushings, Cholangioscopy-Directed Biopsies and Pediatric Forceps Biopsies in Biliary Strictures
Status: TERMINATED
Conditions: Cholangiocarcinoma|Stricture; Bile Duct
Interventions: PROCEDURE: Biopsies of bile duct stricture with pediatric biopsy forceps|PROCEDURE: Biopsies of bile duct stricture with cholangioscopy-directed biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Three Feeding Regimens on Recovery of Uncomplicated Severely Acute Malnourished Children
Status: COMPLETED
Conditions: Uncomplicated Severe Acute Malnutrition
Interventions: OTHER: Ready to Use Therapeutic Food-Centrally produced|OTHER: Ready to Use Therapeutic Food-Locally produced|OTHER: High energy and micronutrient rich foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of NNC 0172-0000-2021 in Healthy Male Subjects and Subjects With Haemophilia A or B
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B|Healthy
Interventions: DRUG: NNC 0172-0000-2021|DRUG: NNC 0172-0000-2021|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Stomopral|DRUG: Nexium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
Status: RECRUITING
Conditions: Inherited Bone Marrow Failure Syndrome|Familial Platelet Disorder With Predisposition to Myeloid Malignancies
Interventions: DRUG: imatinib|DEVICE: TruSight Oncology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Employment-based Reinforcement of Naltrexone Ingestion and Abstinence
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Heroin Dependence|Opioid-Related Disorders|Substance Abuse, Intravenous
Interventions: BEHAVIORAL: employment-based reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Direct Laryngoscopy With Blind Intubation Via Intubating Laryngeal Mask Airway
Status: UNKNOWN
Conditions: Adverse Anesthesia Outcome
Interventions: DEVICE: Intubating Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Previous Pneumococcal Immunization on the Immune Response of Patients With Severe CKD to Prevnar 13
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal Bleeding
Status: COMPLETED
Conditions: Acute Bleeding Esophageal Varices|Portal Hypertension|Cirrhosis
Interventions: DRUG: Somatostatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Infliximab for Immune Checkpoint Inhibitor Induced Colitis
Status: RECRUITING
Conditions: Colitis
Interventions: DRUG: Infliximab|DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation
Status: COMPLETED
Conditions: Coronary Heart Disease|Stable Angina Pectoris|Silent Myocardial Ischemia
Interventions: DEVICE: Orsiro stents|DEVICE: Resolute Integrity® stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs
Status: COMPLETED
Conditions: Trochlear Nerve Diseases
Interventions: DEVICE: Heidelberg Spectralis OCT device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study on The Effect of Multiple Doses of Activated Charcoal on The Pharmacokinetics of a Single Dose of RO4995819
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4995819|DRUG: activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Bioavailability of Pea Protein in Young and Old Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DIETARY_SUPPLEMENT: Pea protein (NUTRALYS ® S85 plus) in water|DIETARY_SUPPLEMENT: Pea protein (NUTRALYS ® S85 plus) within meal|DIETARY_SUPPLEMENT: Whey protein in water|DIETARY_SUPPLEMENT: Whey protein within meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of a Ketone Drink on Blood Glucose Levels in People With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Ketone supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paclitaxel/Carboplatin With or Without Cetuximab in CUP
Status: UNKNOWN
Conditions: Neoplasms, Unknown Primary|Carcinoma
Interventions: DRUG: paclitaxel/carboplatin|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Healthy Live Birth in Women With Prediabetes
Status: RECRUITING
Conditions: Metformin|Prediabetes|In-Vitro Fertilization
Interventions: DRUG: Metformin pretreatment before ovarian stimulation|DRUG: Placebo pretreatment before ovarian stimulation|DRUG: Metformin pretreatment before endometrial preparation for frozen embryo transfer|DRUG: Placebo pretreatment before endometrial preparation for frozen embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Tooth Cleaning Devices on Oral Health
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DEVICE: Manual Toothbrush|DEVICE: Interproximal Cleaning Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Status: NOT_YET_RECRUITING
Conditions: Incisional Hernia of Anterior Abdominal Wall
Interventions: DEVICE: Low molecular weight mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gene and Protein Expression Profiles After Treatment of Actinic Keratoses
Status: RECRUITING
Conditions: Actinic Keratoses
Interventions: DRUG: 5Fluorouracil|DRUG: Imiquimod|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, TaZA CLL Study
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Tafasitamab|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tomato Extracted Lycopene on Postprandial Oxidation and inﬂammation in Healthy Weight Men and Women
Status: COMPLETED
Conditions: Postprandial Oxidation and inﬂammation
Interventions: DIETARY_SUPPLEMENT: Tomato extracted lycopene|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Rifampin Capsules
Status: COMPLETED
Conditions: Anesthesia|Sedation
Interventions: DRUG: HSK3486|DRUG: rifampin , HSK3486
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Doses of GC021109 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GC021109|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning
Status: COMPLETED
Conditions: Speech|Motor Activity
Interventions: BEHAVIORAL: Speech adaptation|BEHAVIORAL: Vibrotactile Discrimination|OTHER: fMRI|BEHAVIORAL: Speech production
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Growth Hormone Treatment in Infants Aged 1 to 2 Years With Chronic Renal Insufficiency (CRI) and Growth Retardation.
Status: COMPLETED
Conditions: Chronic Kidney Disease|Chronic Renal Insufficiency
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children
Status: COMPLETED
Conditions: Fecal Incontinence|Neurogenic Bowel
Interventions: DRUG: Dose Response - NS and USP Glycerin - First Intervention|DRUG: Effectiveness - NS and USP Glycerin - Second Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrospective Study on the Evaluation of the Impact of Augmented Reality Usage in Gynecological Laparoscopy on Patients Operated Between 2017 and 2021 (ImpactRA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myoma;Uterus|Adenomyoma of Uterus
Interventions: PROCEDURE: Gynecological laparoscopic surgery without augmented reality|PROCEDURE: Gynecological laparoscopic surgery with augmented reality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (In Vivo Phase)
Status: NOT_YET_RECRUITING
Conditions: Lymphoma|Head and Neck Cancer
Interventions: DIAGNOSTIC_TEST: spectroscopic measurement|DIAGNOSTIC_TEST: FNA biopsy|DIAGNOSTIC_TEST: histopathology and cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of HES 130 in Balanced and in Unbalanced Solution
Status: COMPLETED
Conditions: Decreased and Nonspecific Blood Pressure Disorders and Shock
Interventions: DRUG: 6% HES 130/0.42 in plasma adapted Ringer's solution|DRUG: 6% HES 130/0.4 in a saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Psychological Interventions for children and adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of IBI939 in Combination With Sintilimab in Patients With Advanced NSCLC
Status: COMPLETED
Conditions: Advanced Lung Cancer
Interventions: BIOLOGICAL: IBI939|BIOLOGICAL: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome
Status: NOT_YET_RECRUITING
Conditions: Wallenberg Syndrome
Interventions: DEVICE: Virtual Reality Therapy|BEHAVIORAL: Conventional dysphagia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vanguard Complete Knee Versus Vanguard High Flex Rotating Platform (RP) Knee Study
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis
Interventions: DEVICE: Vanguard Complete Knee|DEVICE: Vanguard High Flex RP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Lapatinib + Capecitabine in Patients Aged 70 and Over With HER2 Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Metastatic Breast Cancer|70 Years Old Patients and Over|After One Line of Chemotherapy With Trastuzumab
Interventions: DRUG: lapatinib + capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Video Game-assisted and BoNT-A Injection Therapy on Spasticity, Activity and Participation in CP Patients
Status: UNKNOWN
Conditions: Cerebral Palsy, Spastic
Interventions: DRUG: IncobotulinumtoxinA|DEVICE: Video game
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine hydrochloride ophthalmic solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Choline Uptake Study
Status: COMPLETED
Conditions: Choline Uptake|Kinetics
Interventions: DIETARY_SUPPLEMENT: Choline added as a phospholipid|DIETARY_SUPPLEMENT: Choline added as a salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Cerebral Amyloid Angiopathy|Intracerebral Hemorrhage|Hypertensive Hemorrhage, Intracranial|Cognitive Decline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Understanding the Effects of Daily Tea Consumption on Attention, Sleep, and Mood, in Healthy Adults
Status: RECRUITING
Conditions: The Focus of the Study is Healthy Volunteers
Interventions: OTHER: Black tea flavoured, tea drink|OTHER: Black tea flavoured, caffeine-only drink|OTHER: Black tea flavoured, placebo drink|OTHER: Green tea flavoured, tea drink|OTHER: Green tea flavoured, caffeine-only drink|OTHER: Green tea flavoured, placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessing Fever Rates in Children Ages 24 to 59 Months After Live Attenuated Influenza Vaccine (LAIV) or Inactivated Influenza Vaccines (IIV) Using Text Messaging for U.S. Influenza Vaccines in 2012-2013 & 2013-2014
Status: COMPLETED
Conditions: Fever
Interventions: OTHER: text message surveillance for fever
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Chronic Traumatic Encephalopathy
Interventions: DRUG: [F-18]Flornaptitril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Triple Therapy in Diabetic Retinopathy (DRP)
Status: COMPLETED
Conditions: Macular Edema|Diabetic Retinopathy
Interventions: DRUG: triamcinolone and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity
Status: NOT_YET_RECRUITING
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DRUG: Dolutegravir 50 MG plus lamivudine 300 MG； Dolutegravir/lamivudine (50 MG/300 MG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: high power laser|OTHER: low level laser|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Spine Retraction Exercise With and Without Diaphragmatic Breathing in Forward Head Posture.
Status: RECRUITING
Conditions: Forward Head Posture
Interventions: OTHER: Cervical Retraction Exercise|OTHER: Diaphragmatic Breathing|OTHER: Baseline Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants
Status: TERMINATED
Conditions: Breast Augmentation|Breast Reconstruction|Breast Implant Revision
Interventions: DEVICE: Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of CRLX101(NLG207) in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: CRLX101|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Assessment of Rotavin-M1 in Vietnamese Children
Status: COMPLETED
Conditions: Diarrhea|Fever|Nausea|Vomit|Irritability
Interventions: BIOLOGICAL: Rotavin-M1|BIOLOGICAL: cell culture medium in absence of virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial Examining the Effectiveness of Mobile-Based Asthma Action Plans vs. Paper Asthma Action Plans
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Paper Asthma Action Plan|DEVICE: Mobile Phone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin as Enhancer of Psychotherapy Outcomes in Severe Mental Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Mental Illness
Interventions: DRUG: Intranasal Oxytocin|OTHER: Intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglycerides
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypertriglyceridemia
Interventions: DRUG: Gemcabene 150 mg|DRUG: Gemcabene 300 mg|DRUG: Gemcabene 600 mg|DRUG: Gemcabene 900 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Still Climbin': An Intervention to Improve Coping Among Black Sexual Minority Men
Status: RECRUITING
Conditions: Discrimination, Social|Health Care Utilization
Interventions: BEHAVIORAL: CBT Coping Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Escalating Dose and Multiple Dose Study of BAY 1093884 in Subjects With Severe Hemophilia Types A or B, With or Without Inhibitors
Status: COMPLETED
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: BAY1093884|DRUG: BAY1093884
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of the SCS With Different Waveforms Over the Quality of Life (SCS-Quality)
Status: UNKNOWN
Conditions: Failed Back Surgery Syndrome|Spinal Cord Stimulation
Interventions: DEVICE: IPG with Conventional Stimulation|DEVICE: IPG with SCS DTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Bosutinib Administered as Capsule Contents Mixed With Applesauce or Yogurt Relative to Intact Capsules Under Fed Condition
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Bosutinib capsule|DRUG: Bosutinib capsule|DRUG: Bosutinib capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Crenolanib in Subjects With Relapsed/Refractory AML With FLT3 Activating Mutations
Status: COMPLETED
Conditions: Relapsed or Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations
Interventions: DRUG: Crenolanib Besylate (CP-868,596-26)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Passiflora and Meditation on Blood Pressure and Heart Rate
Status: UNKNOWN
Conditions: Heart Rate Fast|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Passiflora incarnata
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism
Status: TERMINATED
Conditions: Type 2 Diabetes|Hypogonadism
Interventions: DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT