pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Normobaric Oxygen Therapy in Acute Ischemic Stroke Trial
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: NBO (Normobaric Oxygen)|DRUG: Room Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of URC102 to Assess the Safety and Efficacy in Gout Patients
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: URC102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing BL123 Versus Ketoconazole in Patients With Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Dapaconazole|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of VP20621 for Prevention of Recurrent Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: VP20621|BIOLOGICAL: VP20621|OTHER: Placebo|BIOLOGICAL: VP20621
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination of PSMA-PET/MR and p2PSA in Early Diagnosis of Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|PSMA|p2PSA
Interventions: DIAGNOSTIC_TEST: Prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chidamide Combined With Cyclophosphamide, Prednisone, Thalidomide in Treatment of Fragile Patients With Relapse/Refratory Peripheral T Cell Lymphoma
Status: UNKNOWN
Conditions: Relapse/Refratory Peripheral T Cell Lymphoma
Interventions: DRUG: C-CPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis|Lumbar Disc Herniation|Lumbar Spondylolisthesis|Lumbar Spondylosis|Lumbar Radiculopathy|Lumbar Spine Instability|Synovial Cyst|Degenerative Disc Disease|Degenerative Spondylolisthesis|Degenerative Intervertebral Discs
Interventions: DRUG: Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.
Status: RECRUITING
Conditions: Tooth Discoloration
Interventions: OTHER: Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA)|OTHER: Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)|OTHER: Placebo gel without any active ingredients.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Osseoanchored Percutaneous Prosthesis Study Evaluating Stable Neural Signal Transmission in Subjects With Transhumeral Amputations
Status: WITHDRAWN
Conditions: Amputation Neuroma|Amputation|Prosthesis User
Interventions: DEVICE: e-OPRA (electronic-Osseoanchored Prosthese for the Rehabilitation of Amputees)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Investigate Safety, Tolerability and Pharmacokinetics of AZD2423 Multiple Doses in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Part 1 - AZD2423 or Placebo|DRUG: Part 2 - AZD2423|DRUG: Part 3 - AZD2423
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measuring the Impact of Dietary Supplementation With a High Fiber, High Antioxidant Aleurone on Biomarkers of Cardiovascular Disease and Gut Microbiota in Adults With High Body Mass Index
Status: COMPLETED
Conditions: Overweight|Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Aleurone|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: DDN-A-0101 (SAD)|DRUG: DDN-A-0101 (MAD)|DRUG: Placebo (SAD)|DRUG: Placebo (MAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Two Interventions on Liver Frailty Index in Pre-frail and Frail Cirrhotic Patients Enlisted for Liver Transplantation
Status: RECRUITING
Conditions: Cirrhosis, Liver
Interventions: OTHER: Physical and nutritional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiotherapy to Treat Patients With Limited Stage of Small Cell Lung Cancer (SCLC)
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: carboplatin|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ABT-384|DRUG: donepezil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Obesity and Cardiovascular Outcomes in Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity Associated Disorder|Myocardial Infarction
Interventions: PROCEDURE: Percutaneous coronary intervention (PCI)|PROCEDURE: Coronary artery bypass grafting (CABG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets at Steady State
Status: COMPLETED
Conditions: Healthy Subjects|Bioavailability|Pharmacokinetics
Interventions: DRUG: Trazodone HCl|DRUG: Trazodone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic S. Salivarius K12 for the Prevention of Upper Respiratory Tract Infection in Nursery-age Children
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection
Interventions: DIETARY_SUPPLEMENT: Probiotic Streptococcus salivarius K12|OTHER: No probiotic supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Fiberoptic Endotracheal Intubation Between the Intubating Laryngeal Tube Suction and the LMA Protector
Status: UNKNOWN
Conditions: Difficult Airway
Interventions: DEVICE: Device intubating Laryngeal Tube Suction Disposable
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Versus Transvaginal Cuff Closure
Status: COMPLETED
Conditions: Vaginal Cuff Dehiscence|Vaginal Hematoma|Vaginal Infection
Interventions: BIOLOGICAL: laparoscopical l cuff closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Macular Degeneration|Wet Macular Degeneration|Retinal Degeneration|Retinal Diseases|Eye Diseases
Interventions: BIOLOGICAL: brolucuzumab 6 mg IVT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Trans Sodium Crocetinate in Patients With Interstitial Lung Disease
Status: TERMINATED
Conditions: Interstitial Lung Disease
Interventions: DRUG: Trans Sodium Crocetinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab, Endostar Combined With Radiotherapy and Chemotherapy for Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Toripalimab, Endostar Combined With Radiotherapy and Chemotherapy|DRUG: IC＋CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Radiation Therapy With or Without Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx
Interventions: DRUG: erlotinib hydrochloride|DRUG: cisplatin|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nationwide Utilization of Danish Government Electronic Letter System for Confirming the Effectiveness of Behavioral Nudges in Increasing InFLUenza Vaccine Uptake Among Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza|Behavior and Behavior Mechanisms
Interventions: BEHAVIORAL: Behavioral Economic Principles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: App-based Versus Slide-based Inter-grader Agreement (IGA) Test for Trachoma Graders
Status: TERMINATED
Conditions: Trachoma
Interventions: OTHER: Inter-grader agreement (IGA) app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Occupational Therapy at Home E-Rehabilitation (OTHER) for Persons Post-stroke
Status: RECRUITING
Conditions: Stroke|eHealth|Occupational Therapy
Interventions: OTHER: OTHER-intervention (Occupational Therapy at Home E-Rehabilitation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Approval Study Protocol for the Simplify Cervical Artificial Disc
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disorder
Interventions: DEVICE: Simplify Disc|OTHER: ACDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovenous RFA Versus Ligation and Striping for Varicose Veins
Status: UNKNOWN
Conditions: Varicose Veins of Lower Limb
Interventions: DEVICE: Radiofrequency ablation for treatment of lower limb varicose veins (ClosureFast, Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Follicle Stimulating Hormone (FSH) (Gonal-f®): Use in Ovulation Induction
Status: COMPLETED
Conditions: Ovulation Induction
Interventions: DRUG: Recombinant FSH (follitropin alpha)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Neurotoxicity in Patients With Metastatic Gastro Intestinal Cancer Taking Phycocare® or Placebo During Oxaliplatin Based Chemotherapy
Status: RECRUITING
Conditions: Metastatic Gastric Cancer
Interventions: OTHER: Phycocare|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine Patch|DRUG: Moclobemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnetic Tape on Autonomic Nervous System in Patients With Low Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: DEVICE: Magnetic Tape® aplication|DEVICE: Kinesiology Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Different Approaches on Palatal Donor Site
Status: COMPLETED
Conditions: Wound Heal
Interventions: DEVICE: Gelatin sponge stabilization with suture and cyanoacrylate|PROCEDURE: Gelatin sponge stabilization with suture and cyanoacrylate and coconut oil application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Exogenous Estrogens on Cotisol Levels During Synacthen Stimulation
Status: UNKNOWN
Conditions: Adrenal Insufficiency|Hypogonadism Female
Interventions: DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis
Status: RECRUITING
Conditions: Suspected Sarcoidosis
Interventions: DEVICE: endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sorafenib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD)
Status: RECRUITING
Conditions: End-Stage Renal Disease (ESRD)
Interventions: DRUG: Avacopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
Status: COMPLETED
Conditions: Chronic Allergic Conjunctivitis
Interventions: DRUG: Dexamethasone|OTHER: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LT F-up Study 16-20 Yrs After Vaccine Dose of Hepatitis B With/Without HBIg in Newborns to HBeAg+ Mothers
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix™ -B|BIOLOGICAL: Hepatitis B immunoglobulin (HBIg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Real World Effectiveness of Ustekinumab in Induction and Maintenance Therapy for Crohn´s Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: BIOLOGICAL: Stelara, Remicade, Entyvio, Humira, Remsima, Flixabi, Inflectra
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-center Trial of Ferric Derisomaltose in Children 0 to <18 Years of Age With Iron Deficiency Anemia
Status: RECRUITING
Conditions: Iron Deficiency, Anaemia in Children
Interventions: DRUG: Ferric Derisomaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia for Postlaminectomy
Status: COMPLETED
Conditions: Laminectomy
Interventions: DRUG: Lidocaine, perineural injection, intraoperatively|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Alternating Current Stimulation in Optic Neuropathy
Status: COMPLETED
Conditions: Optic Nerve Diseases|Optic Nerve Injuries|Optic Neuropathies
Interventions: DEVICE: Repetitive transorbital alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Anthracycline Cardiotoxicity by Echocardiographic Analysis of Myocardial Deformation in 2D Strain
Status: COMPLETED
Conditions: Leukemia|Cardiac Toxicity
Interventions: DEVICE: Echographic analysis of myocardial deformation in 2D strain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy
Status: COMPLETED
Conditions: Otitis Media
Interventions: DRUG: Intranasal fentanyl|DRUG: morphine IM|DRUG: IV morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration|Diabetic Macular Edema
Interventions: DRUG: Faricimab|COMBINATION_PRODUCT: Port Delivery System with Ranibizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lung MRI in the Management of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DEVICE: MRI|OTHER: Thoracic HRCT (standard reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Microbiological Assessment After Chemo-Mechanical Caries Removal Using Papain-based Enzyme Versus Conventional Rotary Tools in Occlusal Carious Lesions
Status: UNKNOWN
Conditions: Microbial Colonization
Interventions: DRUG: Papain-based Chemo-mechanical caries removal agent|DEVICE: conventional rotary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Renal Function
Status: RECRUITING
Conditions: COVID-19 Pneumonia
Interventions: DRUG: GST-HG171 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Food Advanced Glycation Endproducts on Vascular Function in Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Glycated beta-lactoglobulins.|DIETARY_SUPPLEMENT: Non-glycated beta-lactoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Adoptive Cell Therapy Following a Reduced Intensity, Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Ovarian
Status: UNKNOWN
Conditions: Metastatic Ovarian Cancer
Interventions: DRUG: Fludarabine|RADIATION: Radiation|BIOLOGICAL: TIL administration|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
Status: TERMINATED
Conditions: Postoperative Nausea and Vomiting|Respiratory Conditions Due to Other External Agents
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy
Status: TERMINATED
Conditions: Lymphoma|Nonneoplastic Condition
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comprehensive Optimization At-time of Radical Cystectomy Intervention
Status: RECRUITING
Conditions: Bladder Cancer|Radical Cystectomy
Interventions: OTHER: Preop Intervention and Monitored Recovery|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Effectiveness and Safety of Variable Frequency Stimulation Compared With Constant Frequency Stimulation for Patients With Idiopathic Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: Variable Frequency Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects
Status: UNKNOWN
Conditions: Corneal Defect
Interventions: DRUG: ZKY001 eye drops 0.3g:0.006mg|DRUG: ZKY001 eye drops 0.3g:0.012mg|DRUG: ZKY001 simulated eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PDT and Bioceramic Filling on Periapical Healing and Postoperative Pain After Endodontic Retreatment
Status: COMPLETED
Conditions: Apical Periodontitis
Interventions: DRUG: BioRoot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Vernal Keratoconjunctivitis
Interventions: DRUG: NOVA22007 ''Ciclosporin''|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection
Status: COMPLETED
Conditions: Tendinosis|Tendinitis
Interventions: PROCEDURE: Tenotomy (no injection)|DRUG: Ultrasound guided platelet rich plasma injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Sarcoma|Recurrent Sarcoma|Resectable Sarcoma
Interventions: DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DEVICE: Drug Delivery Microdevice|DRUG: Everolimus|BIOLOGICAL: Ganitumab|DRUG: Ifosfamide|DRUG: Irinotecan|DRUG: Pazopanib|DRUG: Polyethylene Glycol|DRUG: Temozolomide|DRUG: Temsirolimus|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck Lesions
Status: COMPLETED
Conditions: Lip and Oral Cavity Squamous Cell Carcinoma|Oral Cavity Verrucous Carcinoma|Precancerous Condition
Interventions: DRUG: vandetanib|OTHER: placebo|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Bevacizumab|DRUG: cyclophosphamide|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 Cases
Status: UNKNOWN
Conditions: Knee Joint Prosthesis Infection|Flap Necrosis|Skin Graft Complications
Interventions: OTHER: patients having had skin coverage of the knee
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Facilitating Follow-Up Adherence for Abnormal Pap Smears
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: BEHAVIORAL: Cognitive-affective barriers counseling|BEHAVIORAL: Cognitive-affective barriers counseling via brochure|BEHAVIORAL: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients
Status: COMPLETED
Conditions: Ascitic Cirrhosis|Hyperactivation of Sympathetic Nervous System
Interventions: DRUG: clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intradermal Fractional Dose IPV (fIPV) in Combination With dmLT
Status: ACTIVE_NOT_RECRUITING
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Intradermal fractional dose inactivated polio vaccine (fIPV) in combination with recombinant double mutant heat labile toxin, LT(R192G/L211A), (dmLT)|BIOLOGICAL: Intradermal fractional dose inactivated polio vaccine (fIPV)|BIOLOGICAL: Monovalent oral poliomyelitis vaccine (mOPV), Sabin strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Effectiveness of the Akreos MI Five-0 Intraocular Lens.
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: Akreos MI Five-O
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketone Supplementation in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Ketone Monoester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1026706 in Male and Female Healthy Subjects and Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: BI 1026706|DRUG: Placebo to BI 1026706
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib in Combination With Cyclophosphamide and Etoposide for Children
Status: COMPLETED
Conditions: Relapsed Solid Tumors|Refractory Solid Tumors|Relapsed Leukemia|Refractory Leukemia
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO)
Status: COMPLETED
Conditions: Smoking Cessation|Nicotine Dependence
Interventions: DRUG: NFL-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Relative Bioavailability of a Tablet Formulation of GDC-0941 and the Effect of Ketoconazole on the Pharmacokinetics of the GDC-0941 Tablet
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GDC-0941|DRUG: GDC-0941|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of an Exogenous Phytase on Iron Absorption From LNS Added to Complementary Foods
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: micronutrient powder|DIETARY_SUPPLEMENT: micronutrient powder (containing FeSO4), phytase|DIETARY_SUPPLEMENT: Iron pyrophosphate (FePP)|DIETARY_SUPPLEMENT: Iron sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants
Status: COMPLETED
Conditions: Pain|Neonatal Infections|Analgesia
Interventions: DRUG: FentanyL|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia With Type2DM
Interventions: DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery
Status: WITHDRAWN
Conditions: Breast Cancer|Kidney Cancer|Lung Cancer|Melanoma (Skin)|Testicular Germ Cell Tumor
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: MicroRNA as Markers in Testicular Cancer
Status: RECRUITING
Conditions: Testicular Germ Cell Cancer|Seminoma|Non-Seminoma Testicular Cancer|Stage I Testicular Cancer|Stage II Testicular Cancer|Stage III Testicular Cancer|Stage IV Testicular Cancer|Relapse Testicular Cancer
Interventions: OTHER: Biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-dose Gemcitabine Combined With Nivolumab for Second-line and Above Line Treatment of NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Gemcitabine Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label, Multi-Center Study, Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Facial Fat Grafting
Status: ACTIVE_NOT_RECRUITING
Conditions: Facial Atrophy and Loss of Contour
Interventions: DEVICE: SyntrFuge System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Consolidative Radiotherapy for Oligoprogressive in Non-small Cell Lung Carcinoma
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer|Oligoprogressive
Interventions: RADIATION: Local consolidative radiation therapy|DRUG: Standard of care radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprainguinal Fascia Iliaca Block Versus Lumbar Erector Spinae Plane Block for Oncologic Thigh Surgery
Status: NOT_YET_RECRUITING
Conditions: Perioperative Pain
Interventions: PROCEDURE: Ultrasound-Guided Suprainguinal Fascia Iliaca Block Versus Lumbar Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation in Heart Failure Patients With Anemia: The IRON-HF Study
Status: UNKNOWN
Conditions: Heart Failure|Anemia
Interventions: DRUG: Iron Sucrose IV 200mg, once a week, for 5 weeks|DRUG: Ferrous sulfate 200mg PO TID, for 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging Predictors of Antidepressant Treatment Outcome
Status: WITHDRAWN
Conditions: Depression
Interventions: DRUG: Placebo|DRUG: Citalopram|DRUG: Fast acting antidepressant-like treatment. administered i.v. during the fMRI scanning session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression
Status: COMPLETED
Conditions: Metastatic Epidural Spinal Cord Compression
Interventions: PROCEDURE: Surgical excision of the metastatic process|RADIATION: Radiotherapy of the metastatic spine process
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms
Status: COMPLETED
Conditions: Bone Metastases
Interventions: RADIATION: Hypofractionated Radiation Treatment|RADIATION: One Radiation Treatment|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seattle-PAP Bubble Nasal CPAP and Work of Breathing
Status: COMPLETED
Conditions: Respiratory Distress Syndrome In Premature Infants|Bronchopulmonary Dysplasia|Newborn Primary Sleep Apnea
Interventions: DEVICE: Seattle-PAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sonoelastographic Changes After Low Energy Extracorporeal Shock Wave Therapy (ESWT) in Plantar Fasciitis
Status: UNKNOWN
Conditions: Chronic Plantar Fasciitis
Interventions: DEVICE: Extracoporeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Laser Acupuncture and Renal Biopsy
Status: COMPLETED
Conditions: Pain|Anxiety
Interventions: DEVICE: Aculaser applied to kidney points|DEVICE: Aculaser applied to sham points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Safety and Efficacy of Empagliflozin as Add on to GLP-1 RA
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: empagliflozin 10mg|DRUG: empagliflozin 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma
Status: UNKNOWN
Conditions: Blood Loss
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: 5-fluorouracil 4% (Tolak)|DEVICE: Dexeryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Atherosclerosis, Coronary|Myocardial Ischemia|Ischemic Heart Disease|Acute Coronary Syndrome|Angina Pectoris
Interventions: DEVICE: Orsiro DES
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Gut Microbiota in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Cachexia
Interventions: OTHER: collection of clinical data and biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung Cancer
Status: TERMINATED
Conditions: Esophagitis
Interventions: DRUG: GC4419 (avasopasem manganese)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Low Residue Diet Versus Clear Liquids Following Elective Colorectal Surgery
Status: COMPLETED
Conditions: Nausea/Vomiting
Interventions: DIETARY_SUPPLEMENT: Clear Liquids|DIETARY_SUPPLEMENT: Regular Solid|DEVICE: Abstats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Diltiazem and Metoprolol in the Management of Acute Atrial Fibrillation or Atrial Flutter
Status: COMPLETED
Conditions: Heart Rate and Rhythm Disorders
Interventions: DRUG: Metoprolol|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Status: COMPLETED
Conditions: Pain Management
Interventions: DRUG: Morphine Sulfate|DRUG: Oxycodone|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Third Dose of COVID-19 Vaccine(Vero Cell), Inactivated in the Elderly
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-19 Vaccine (Vero cell), Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Yokohama Assessment of Fluvastatin, Pravastatin, Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Yokohama-ACS)
Status: COMPLETED
Conditions: Coronary Disease|Hypercholesterolemia
Interventions: DRUG: Fluvastatin|DRUG: Pravastatin|DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Postoperative Analgesia Between Subarachnoid Block With 2-chloroprocaine Versus General Anesthesia for Knee Arthroscopy
Status: TERMINATED
Conditions: Knee Arthroscopy|General Anesthesia|Subarachnoid Block
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Subarachnoid block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Multiple Myeloma
Interventions: OTHER: Best Practice|OTHER: Cognitive Intervention|OTHER: Comprehensive Geriatric Assessment|OTHER: Nutritional Intervention|PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
Status: RECRUITING
Conditions: Human Immunodeficiency Virus|Alcohol-Related Disorders|Drug Use|Substance Use
Interventions: BEHAVIORAL: Khanya
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy, Immunogenicity, and Safety of V503 in Chinese Males (V503-052)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: 9vHPV Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Behavioral Activation|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Characteristics of CKD-4101 (Mycophenolate Mofetil) Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CKD-4101 tablet|DRUG: Mycophenolate Mofetil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALL
Status: RECRUITING
Conditions: Precursor B-Cell Lymphoblastic Leukemia
Interventions: DRUG: Dexamethasone|DRUG: Blinatumomab|DRUG: Venetoclax|DRUG: Inotuzumab ozogamicin|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Open-Label Flexible-dose Brexpiprazole as Maintenance Treatment in Adolescents With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Heat on Rivastigmine TDS Products
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Rivastigmine (RLD) transdermal patch|DRUG: Rivastigmine (generic) transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer
Status: TERMINATED
Conditions: Malignant Neoplasm|Metastatic Malignant Neoplasm to the Bone
Interventions: RADIATION: virtual non-calcium dual-energy computed tomography|RADIATION: computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probiotics Use in the Chronic Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: Peritonitis|Malnutrition
Interventions: DRUG: Pro-biotics|DIETARY_SUPPLEMENT: Oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Amitriptyline Hydrochloride Tablets
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Amitriptyline Hydrochloride 25Mg Tablet（Hunan Dongting）|DRUG: Amitriptyline Hydrochloride 25Mg Tablet（Sandoz）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Concurrent Use Lymphoseek & Indocyanine Green in Sentinel Lymph Node Detection in Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: DRUG: Lymphoseek|DEVICE: Single Photon Emission Computed Tomography (SPECT)|DRUG: Indocyanine Green (ICG)|DEVICE: Neoprobe Gamma Detection System NPB11L(Model1102)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Forced Air Versus Endovascular Warming in Polytrauma Patients
Status: SUSPENDED
Conditions: Polytrauma|Hypothermia
Interventions: DEVICE: Forced Air Warming|DEVICE: Warming with endovascular catheter + forced air warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Jin Fu Kang in Comb w/Docetaxel for Patients w/Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Jin Fu Kang
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Expectancy for Cognitive Enhancement in College Students Using Prescription Stimulants Nonmedically
Status: NOT_YET_RECRUITING
Conditions: Prescription Stimulants|Expectations|Deception
Interventions: DRUG: Adderall 10Mg Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH