pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Integrated Research on Acute Malnutrition in Chad
Status: COMPLETED
Conditions: Acute Malnutrition in Childhood|Wasting
Interventions: BEHAVIORAL: BCC|DIETARY_SUPPLEMENT: Preventive supplement|DIETARY_SUPPLEMENT: MNP|OTHER: Water purification input|BEHAVIORAL: Family MUAC|BEHAVIORAL: Screening by care group|BEHAVIORAL: CMAM compliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of exSALT SD7™ Compared to Xeroform® Petrolatum Dressing for the Management of Partial Thickness Donor Sites
Status: UNKNOWN
Conditions: Wound Healing|Wound Infection
Interventions: DEVICE: The exSALT™ SD7 Wound Dressing|DEVICE: Xeroform® Petrolatum Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minnelide in Adult Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Minnelide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Oral Vinorelbine or Observation After Vinorelbine-Docetaxel First Line Chemotherapy in Advanced Breast Ca
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine-Docetaxel|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dose Fractionation of Testosterone Cypionate on Transgender Men With Erythrocytosis
Status: RECRUITING
Conditions: Testosterone|Transsexualism|Hematologic Diseases
Interventions: DRUG: Testosterone Cypionate 100 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Training in Occupational Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Diseases|Mental Health Disorder|Back Pain, Low|Anxiety Disorders|Depression
Interventions: DEVICE: Virtual Reality with Beat Saber
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hydroxyapetite Nanoparticles, Tricalcium Phosphate Nanoparticles, and PRF for Treatment of Gingival Recession
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: coronally advanced flap|OTHER: Nanocrystalline hydroxyapatite loaded in PRF|OTHER: Nanocrystalline tricalcium phosphate loaded in PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of NUTRICAN to Improve Nutritional Status in Cancer Patients
Status: RECRUITING
Conditions: Malnutrition; Protein|Cancer, Lung|Cancer Cervix
Interventions: DIETARY_SUPPLEMENT: NUTRICAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Assess the Safety and Pharmacokinetics of DA-2802 319mg and Viread 300mg in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Viread 300mg|DRUG: DA-2802 319mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Over-the-counter Toothpastes on Chemotherapy-induced Oral Mucositis
Status: TERMINATED
Conditions: Mucositis|Neoplasms
Interventions: DRUG: Oral Defense Toothpaste|DRUG: Crest Toothpaste|DRUG: Magic Mouth Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Trifluridine/Tipiracil (Also Known as S 95005 or TAS-102) in Patients With a Pretreated Colorectal Cancer That Has Spread (Metastatic).
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/Tipiracil hydrochloride (S95005)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
Status: COMPLETED
Conditions: Diffuse Intrinsic Pontine Glioma|Malignant Glioma of Brain|High Grade Glioma|Bithalamic High Grade Glioma|Brainstem Glioma|Glioblastoma|Anaplastic Astrocytoma
Interventions: DRUG: ribociclib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Interventional ICE Imaging Trial
Status: NOT_YET_RECRUITING
Conditions: Structural Heart Diseases|Atrial Septal Defect|Patent Foramen Ovale|Arrhythmias, Cardiac|Atrial Fibrillation|Supraventricular Tachycardia|Valve Disease, Heart
Interventions: DEVICE: Arch EchoTM Intracardiac Ultrasound catheter and ultrasound system|DEVICE: SOUNDSTAR 3D Diagnostic Ultrasound catheter and ACUSON P500 system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment for Subjects With Unresectable Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Cancer|Melanoma
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Simulation Training Tool to Identify Lesions Requiring Further Screening for Melanoma
Status: COMPLETED
Conditions: Skin Simulation Model|Mastery Learning Model to Simulation Training for Visual Screening for Melanoma and Skin Biopsy
Interventions: OTHER: Simulation teaching session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of JNJ-64281802 for the Prevention of Dengue Infection
Status: RECRUITING
Conditions: Dengue
Interventions: DRUG: JNJ-64281802|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Status: UNKNOWN
Conditions: Acute Exacerbation of COPD|Acute Exacerbation of Bronchiectasis|Acute Exacerbation of Asthma|Interstitial Lung Disease|Neuromuscular Diseases|Obesity Hypoventilation Syndrome|Acute Respiratory Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Percutaneous Vertebroplasty Versus Standard Conservative Treatment in Thoracolumbar Vertebral Fractures
Status: COMPLETED
Conditions: Vertebral Fracture
Interventions: DEVICE: Early percutaneous vertebroplasty (EPV)|DEVICE: Standard Conservative treatment (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Surgery With or Without Internal Radiation Therapy Compared With Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Stage I Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: PROCEDURE: therapeutic conventional surgery|RADIATION: iodine I 125|RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: senofilcon C|DEVICE: comfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Education With Balance Exercise in Improving Balance and Reducing the Fear of Falls in Elderly
Status: COMPLETED
Conditions: Distorted; Balance
Interventions: DEVICE: GROUP A education programme as well as balance training exercises|OTHER: GROUP B on-platform training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Occlusion With WATCHMAN® Device in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic Kidney Disease on Hemodialysis
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Diseases|Renal Disease|Bleeding|Arrhythmias, Cardiac|Cardiovascular Diseases
Interventions: OTHER: Non Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulmonary Vein Isolation Plus Left Atrial Slow Zone Mapping and Ablation
Status: WITHDRAWN
Conditions: Atrial Arrhythmias
Interventions: DEVICE: AcQMap High Resolution Imaging and Mapping System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Blood Loss Anemia|Extracorporeal Membrane Oxygenation Complication
Interventions: OTHER: Red Blood Cell Transfusion|OTHER: Red Blood Cell Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Focused Ultrasound for Drug-resistant Epilepsy
Status: RECRUITING
Conditions: Focused Ultrasound|MR-guided FUS|Drug Refractory Epilepsy|Drug Resistant Epilepsy|Medication Resistant Epilepsy
Interventions: DEVICE: Exablate 4000 Transcranial MRgfUS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qualitative Study of Suicidal Recrudescence Among Adolescents in November 2021
Status: RECRUITING
Conditions: Suicide|COVID-19
Interventions: BEHAVIORAL: STAI-Y|BEHAVIORAL: BDI scale|BEHAVIORAL: M.I.N.I.Kid|BEHAVIORAL: PCL-5
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: VY-AADC02|OTHER: Sham (Placebo) Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Wounds in Diabetic Foot Syndrome With Allogeneic Adipose Derived Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: Application of allogeneic ADSC stem cells in fibrin gel|PROCEDURE: Standard care in diabetic foot ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Rapamycin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining the Operating Parameters for a Rebound-esthesiometer
Status: UNKNOWN
Conditions: Corneal Sensation Reduced|Corneal Dystrophy|Corneal Degeneration|Corneal Transplant Failure|Herpetic Keratitis
Interventions: DEVICE: Esthesiometer measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Bioactive Injectable Resin Composite in Posterior Restorations
Status: UNKNOWN
Conditions: Dental Restoration Failure
Interventions: OTHER: Beautifil Flow Plus X F00 injectable composite|OTHER: Tetric N ceram resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Optimal Dose of Sugammadex in Elective Surgery
Status: COMPLETED
Conditions: Time of a TOF Ratio >0,9
Interventions: DRUG: Sugammadex Injection [Bridion]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues
Status: RECRUITING
Conditions: Breast Carcinoma|Colon Carcinoma|Esophageal Carcinoma|Gastric Carcinoma|Head and Neck Carcinoma|Kidney Carcinoma|Lung Carcinoma|Ovarian Carcinoma|Pancreatic Carcinoma|Solid Neoplasm|Uterine Corpus Cancer
Interventions: PROCEDURE: Computed Tomography|RADIATION: Gallium Ga 68 FAPi-46|RADIATION: Gallium Ga 68-labeled PSMA-11|PROCEDURE: Positron Emission Tomography|RADIATION: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 7T MRI for Light Therapy in Patients With Mild Cognitive Impairment and Mild AD
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DEVICE: Lighting Intervention Therapy|DEVICE: Sham LIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study Between Contrast Spread and Loss of Resistance Techniques
Status: COMPLETED
Conditions: Cervical Radiculopathy|Neck Pain|Disc Prolapse With Radiculopathy
Interventions: PROCEDURE: Epidural space identification with cervical epidural steroid injection employing CST and LORT.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: DEVICE: HBOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cesarean 123 Trial: Randomized Trial Comparing Single, Double and Triple Layer Uterine Closures During Cesarean Delivery
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related
Interventions: PROCEDURE: Uterine layers closed|DEVICE: Suture Type|PROCEDURE: Endometrium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DE-111 Against Timolol Ophthalmic Solution 0.5%
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DE-111 ophthalmic solution|DRUG: Timolol ophthalmic solution 0.5%|DRUG: Placebo ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment
Status: COMPLETED
Conditions: Apical Periodontitis|Pulp Disease, Dental
Interventions: DRUG: Iron oxide nanoparticles treatment Ferumoxytol/H2O2|DRUG: NaOCl|DRUG: NaCl|DRUG: supplementary irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of 7 Days Treatment With a Novel Analgesic in Subjects With Peripheral Neuropathic Pain
Status: TERMINATED
Conditions: Neuralgia
Interventions: DRUG: GRT6010|DRUG: Pregabalin|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral LGD-4665 Versus Placebo in Adults With Immune Thrombocytopenic Purpura (ITP) for 6 Weeks Plus Open Treatment Continuation
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: LGD-4665|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASPIRE Pilot: Comparing Self-collected HPV Testing With Visual Inspection With Acetic Acid Screening for Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: PROCEDURE: HPV self-colleciton|PROCEDURE: visual inspection with acetic acid (VIA)|DRUG: 3-5% acetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Treating Cognition in Schizophrenia With Atomoxetine and Cognitive Remediation
Status: COMPLETED
Conditions: Cognition in Schizophrenia
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Therapy on Nausea, Vomiting and Anxiety Levels in Children
Status: NOT_YET_RECRUITING
Conditions: Music Therapy|Nausea|Anxiety|Cancer|Vomiting|Children, Only
Interventions: OTHER: Music Therapy|OTHER: antiemetic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oxaliplatin and 5-FU Based Preoperative Chemoradiation
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Chemoradiation|DRUG: 5-FU|RADIATION: Preoperative chemoradiation|PROCEDURE: Pelvic surgery|DRUG: Neoadjuvant oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Intestinal Absorption in Patients With Chronic Obstructive Pulmonary Disease and Cor Pulmonale
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Cor Pulmonale
Interventions: DIAGNOSTIC_TEST: Absorption test with D-xylose and zink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Antigen-specific T Cells in Patients With Antisynthetase Syndrome and Interstitial Lung Disease
Status: RECRUITING
Conditions: Antisynthetase Syndrome
Interventions: DIAGNOSTIC_TEST: BAL antigen-specific Th1 cells and Th17 cells, ILC and MAIT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examination of the Effectiveness of Nasal Irrigation Techniques in Infants With Nasal Congestion
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Nasal Congestion and Inflammations
Interventions: OTHER: group low-volume irrigation|OTHER: group high-volume irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dementia and Disability Simulation for College Nursing Students' Senior Activity Facilitation Skills
Status: ENROLLING_BY_INVITATION
Conditions: Dementia
Interventions: OTHER: DDS program|OTHER: dementia course with no DDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Elucidate Outcomes of Elective High-grade/Total Occlusion Intracranial Arteries Using Low-profile Self-expanding Stent
Status: COMPLETED
Conditions: Intracranial Atherosclerosis|Stent Stenosis|Ischemic Stroke
Interventions: PROCEDURE: Intracranial stenting with Credo® stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
Status: RECRUITING
Conditions: Primary Progressive Aphasia|Logopenic Progressive Aphasia|Non-Fluent Primary Progressive Aphasia
Interventions: DEVICE: Active tDCS + Language Therapy|DEVICE: Sham tDCS + Language Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Transient Ischemic Attack
Interventions: DEVICE: Septal Occluder Device|DRUG: Antiplatelet Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: erlotinib hydrochloride|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Diabetic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: LY3526318|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Transcutaneos Nerve Stimulations in Women With Idiopathic Overactive Bladder
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder, Overactive
Interventions: OTHER: Transcutaneous MPN stimulation (T-MPNS)|OTHER: Transcutaneous tibial nerve stimulation (TTNS)|OTHER: BT (Control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Accelerated Intermittent Theta-burst Stimulation to Modify Cognitive Function and Balance in Dementia and Memory Loss
Status: NOT_YET_RECRUITING
Conditions: Dementia Alzheimers
Interventions: DEVICE: Active Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Mesenchymal Stem Cells for Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: System; Lupus Erythematosus
Interventions: DRUG: Low Dose Mesenchymal Stem Cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Carfilzomib Plus Melphalan and Prednisone in Elderly Untreated Patients With Multiple Myeloma (CARMYSAP)
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Melphalan|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Disparities in the Quality of Advance Care Planning for Older Adults
Status: COMPLETED
Conditions: Metastatic Cancer|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Parkinson Disease|Interstitial Lung Disease|Amyotrophic Lateral Sclerosis|End Stage Liver Disease|End Stage Renal Disease|Diabetes Complications
Interventions: BEHAVIORAL: Respecting Choices First Steps|BEHAVIORAL: Five Wishes Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess Efficacy of Nicorandil+Atenolol vs Atenolol in Treatment of Chronic Stable Angina.
Status: UNKNOWN
Conditions: Chronic Stable Angina
Interventions: DRUG: Nicorandil|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BFR Rehab After Achilles Tendon Rupture
Status: RECRUITING
Conditions: Achilles Tendon Rupture
Interventions: DEVICE: Blood flow restriction with Delfi Personalized Tourniquet System (PTS)|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm
Status: RECRUITING
Conditions: Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts|Myeloproliferative Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|DRUG: Decitabine and Cedazuridine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UGYTEX® Mesh Versus Subvesical Plication in the Surgical Treatment of Bladder Prolapse
Status: COMPLETED
Conditions: Cystocele
Interventions: DEVICE: UGYTEX|PROCEDURE: No mesh.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Utidelone Based Neoadjuvant Treatment on Early High-risk or Locally Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Neoadjuvant Therapy
Interventions: DRUG: Utidelone|DRUG: Carboplatin|DRUG: Epirubicin|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sepsis-induced Immunosuppression Base on QuantiFERON Monitor® in Septic Shock
Status: WITHDRAWN
Conditions: Septic Shock
Interventions: DIAGNOSTIC_TEST: QuantiFERON Monitor®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Light Emitting Diode in the Treatment of Genitourinary Syndrome of Menopause
Status: RECRUITING
Conditions: Atrophy;Vaginal
Interventions: DEVICE: Light Emitting Diode|DEVICE: Sham Light Emitting Diode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Alzheimer Disease|Vascular Dementia|Mild Cognitive Impairment|Parkinsons Disease With Dementia|Dementia With Lewy Bodies|Mixed Dementia
Interventions: DEVICE: In-laboratory polysomnography|DEVICE: Home Sleep Apnea Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: GH35 Tablets for Advanced Solid Tumors: A Study on Safety and Early Results
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors Harboring With G12C Mutation
Interventions: DRUG: GH35 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Good Bacteria on Nonalcoholic Fatty Liver Disease in Diabetics
Status: TERMINATED
Conditions: Fatty Liver|Hepatic Steatosis|Diabetes Mellitus|Liver Diseases
Interventions: DRUG: Probiotic-containing powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Temperature and Pain in Laparoscopy
Status: COMPLETED
Conditions: Intraoperative Temperature|Postoperative Pain|Laparoscopy
Interventions: DEVICE: 3M™ Bair Hugger™|DEVICE: F&P HumiGard™ Surgical Humidification System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra Articular Injection of Ozone With Corticosteroids vs PRGF in Knee Osteoarthritis
Status: COMPLETED
Conditions: Intra Articular Injection|Corticosteroids|Plasma Rich in Growth Factors|Knee Osteoarthritis
Interventions: DRUG: Intra-articular Ozone and corticosteroids|DRUG: intra-articular PRGF Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of MEDI7510 in Older Adults
Status: TERMINATED
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: MEDI7510|BIOLOGICAL: IIV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotics and Its Associated Factors on Aflatoxin Biomarkers
Status: COMPLETED
Conditions: Aflatoxicosis
Interventions: OTHER: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency
Status: COMPLETED
Conditions: Pre-Exposure Prophylaxis|HIV Infections|Pregnancy Related
Interventions: OTHER: PrEP Optimization Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Ventilator Associated Pneumonia With Toothbrushing in Oral Care of Critically Ill Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Critical Care|Mechanical Ventilation|Ventilator Associated Pneumonia Prevention|Toothbrushing|Oral Care
Interventions: OTHER: Toothbrushing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate Ospemifene in the Treatment of Vulvar and Vaginal Atrophy in Postmenopausal Women
Status: COMPLETED
Conditions: Atrophy|Vaginal Diseases
Interventions: DRUG: Ospemifene 30 mg|DRUG: Ospemifene 60 mg|DRUG: Placebo|DRUG: Nonhormonal vaginal lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer
Status: COMPLETED
Conditions: Locally Advanced Malignant Neoplasm|Oral Cancer|Oropharyngeal Carcinoma|Effects of Chemotherapy
Interventions: DRUG: Neo-adjuvant Erbitux-based chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Estradiol Vaginal Cream to Estrace® Cream in Females With Atrophic Vaginitis
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DRUG: Estradiol|DRUG: Placebos|DRUG: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)
Status: COMPLETED
Conditions: Erosive Gastroesophageal Reflux Disease|Non-Erosive Reflux Disease
Interventions: DRUG: Pantoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Bioavailability, Safety and Tolerability of a Solid Dosage Formulation Relative to a Suspension of JNJ-54175446 in Healthy Male and Female Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54175446 (capsule)|DRUG: JNJ-54175446 (suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Cognitive Impairment
Interventions: OTHER: Acupuncture|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: RAD001|DRUG: RAD001, sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restricted High-Intensity Treadmill Training on Independently Ambulating Chronic Ischemic CVA Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Stroke, Ischemic|Ambulation Disorder, Neurologic|Chronic Stroke
Interventions: OTHER: Blood Flow Restricted High Intensity Treadmill Training|OTHER: HITT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Anemia|Chronic Kidney Disease|Metabolic Acidosis
Interventions: DRUG: Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use and Effectiveness of Balloon for Endobronchial Ultrasonography
Status: COMPLETED
Conditions: Lung Cancer Staging
Interventions: DIAGNOSTIC_TEST: Endobronchial biopsy with the use of a balloon attached to the echo-bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Advanced Cancer of the Mouth, Pharynx, or Larynx
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: fluorouracil|DRUG: hydroxyurea|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Clinical Application of MolecuLight Bacterial Fluorescence Imaging in Wound Debridement
Status: UNKNOWN
Conditions: Infection, Surgical Site
Interventions: DEVICE: MolecuLight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Range-finding Study of ASP1585 in Chronic Kidney Disease Patients on Hemodialysis With Hyperphosphatemia
Status: COMPLETED
Conditions: Chronic Kidney Disease Patients on Hemodialysis With Hyperphosphatemia
Interventions: DRUG: ASP1585
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Phase I and Phase II: LAE001/prednisone + afuresertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROTein to Enhance outComes of (Pre)Frail paTients Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Frail Older Adult Syndrome|Nutrition Poor|Cardiovascular Morbidity
Interventions: DIETARY_SUPPLEMENT: ISOlution protein supplement|DIETARY_SUPPLEMENT: Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsewatch: Smartwatch Monitoring for Atrial Fibrillation After Stroke
Status: COMPLETED
Conditions: Stroke|Atrial Fibrillation
Interventions: DEVICE: Testing Devices|DEVICE: Cardea Solo by Cardiac Insight|DEVICE: Kardia Mobile by AliveCor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Restylane® for the Treatment of Tear Trough Deformity
Status: COMPLETED
Conditions: Tear Trough Eyelid Deformity
Interventions: DEVICE: Restylane®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder
Status: RECRUITING
Conditions: PTSD|Stress Disorders, Traumatic|Stress Disorders, Post-Traumatic|Trauma and Stressor Related Disorders|Mental Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7-hydroxystaurosporine and Cisplatin in Treating Patients With Advanced Malignant Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: cisplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Teamwork for Neonatal Resuscitation
Status: COMPLETED
Conditions: Teamwork During Neonatal Resuscitation
Interventions: BEHAVIORAL: Teamwork training|BEHAVIORAL: Standard NRP curriculum|BEHAVIORAL: Skills practice with low-fidelity mannequin|BEHAVIORAL: Skills practice with high-fidelity mannequin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Results of Middle-sized Posterior Malleolus Fractures: Fixed Versus Non-fixed
Status: COMPLETED
Conditions: Ankle Fractures|Posterior Malleolus Fractures
Interventions: PROCEDURE: Internal fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eflornithine With or Without Triamcinolone in Preventing Nonmelanoma Skin Cancer in Patients With Actinic Keratosis
Status: COMPLETED
Conditions: Non-melanomatous Skin Cancer|Precancerous/Nonmalignant Condition
Interventions: DRUG: eflornithine|DRUG: triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of 2-Octyl Cyanoacrylate (2-OCA) With Four Interrupted Sutures in Adult Male Circumcision
Status: NOT_YET_RECRUITING
Conditions: Phimosis|Paraphimosis
Interventions: PROCEDURE: Circumcision wound closure using 2-octyl cyanoacrylate glue with four interrupted sutures|PROCEDURE: Circumcision wound closure using continuous sutuing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dose Dense Gemcitabine and Cisplatin (DD GC) In Patients With Muscle-Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Gemcitabine and Cisplatin (DD GC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-IV: (LONG-DES-IV)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Cypher|DEVICE: Endeavor Resolute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer
Status: COMPLETED
Conditions: HER2 Positive Breast Cancer
Interventions: DRUG: tucatinib|DRUG: capecitabine|DRUG: trastuzumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Exercises on Vasomotor Symptoms in Middle Aged Women
Status: COMPLETED
Conditions: Hot Flashes|Menopause
Interventions: OTHER: Resistance and Aerobic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders
Status: RECRUITING
Conditions: Melanoma Stage IV|Head and Neck Squamous Cell Carcinoma|Cutaneous Squamous Cell Carcinoma|MSI-High|Clear Cell Renal Cell Carcinoma|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Fecal Microbiota Transplant (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-vitrectomy Intravitreal Ranibizumab for Patients With Proliferative Diabetic Retinopathy Combined With Diabetic Macular Edema
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|OTHER: Sham injection|PROCEDURE: Pars plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aclidinium Bromide at Two Dose Levels Versus Placebo Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide 200 μg bid|DRUG: Aclidinium bromide 400 μg bid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Of AJCC Stage IIB, IIC, III And IV Melanoma Patients With A Multi-Epitope Peptide Vaccine Using GM-CSF DNA As An Adjuvant: A Pilot Trial To Assess Safety And Immunity
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: GM-CSF DNA, NSC 683472 gp100: 209-217(210M), NSC 699048 Tyrosinase: 368-376(370D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole
Status: COMPLETED
Conditions: Restless Legs Syndrome|Restless Legs Syndrome (RLS)
Interventions: DRUG: ropinirole Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: RABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritis
Status: TERMINATED
Conditions: RheumatoId Arthritis
Interventions: BIOLOGICAL: Infliximab|BIOLOGICAL: Adalimumab|BIOLOGICAL: Etanercept|BIOLOGICAL: Golimumab|BIOLOGICAL: Certolizumab Pegol|BIOLOGICAL: Infliximab biosimilar|BIOLOGICAL: Etanercept biosimilar|BIOLOGICAL: Infliximab biosimilar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
Status: COMPLETED
Conditions: Venous Thromboembolism|Postpartum Period|Aspirin
Interventions: DRUG: Aspirin 81 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Male External Catheters' Comparison of Comfort and Efficacy
Status: COMPLETED
Conditions: Non-invasive Urine Output Management
Interventions: DEVICE: PureWick Male External Catheter|DEVICE: Sage PrimoFit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VR Based Therapy to Treat Anxiety in Dual Diagnosis
Status: NOT_YET_RECRUITING
Conditions: Dual Diagnosis|Psychosis|Agoraphobia|Social Anxiety Disorder|Substance Use Disorder
Interventions: BEHAVIORAL: Cognitive Miljeu Therapy|BEHAVIORAL: Virtual Reality based CBT for Anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Cytokine Storms in Severe COVID-19 Patients With Autologous Activated Platelet-rich Plasma Therapy
Status: UNKNOWN
Conditions: Covid19|Sars-CoV-2 Infection|ARDS, Human|Severe covid19
Interventions: COMBINATION_PRODUCT: autologous activated platelet-rich plasma|DRUG: Avigan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Randomised Controlled Trial of Posturing Following Surgery for Full-thickness Macular Hole
Status: COMPLETED
Conditions: Full Thickness Macular Hole
Interventions: PROCEDURE: Postoperative face-down posturing|PROCEDURE: Postoperative non-posturing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Trastuzumab|DRUG: Endocrine Therapy|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Ketamine as an Anaesthetic During Electroconvulsive Therapy
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Ketamine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT