pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Camrelizumab After Completion of Radiotherapy for Oligometastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Oligometastasis|Radiotherapy
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symbiotic Yogurt, Calcium Absorption and Bone Health in Young Adult Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) With Oxaliplatin In Patients With Peritoneal Carcinomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Carcinomatosis
Interventions: DRUG: Oxaliplatin|DRUG: Oxaliplatin & Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Cortical Stimulation in the Treatment of Stroke Patients With Upper Extremity Hemiparesis
Status: UNKNOWN
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: Cortical Stimulation and rehabilitation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Treatment of Periodontis on Endothelial Function in Patients With Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Cardiovascular Disease in Obstructive Sleep Apnea
Interventions: PROCEDURE: scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Velcade,Thalidomide, and Dexamethasone Versus Velcade and Dexamethasone Versus Velcade, Melphalan, and Prednisone
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Melphalan|DRUG: Prednisone|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Chronic Hepatitis C Infection in Adults With Genotype 1b Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-450/r/ABT-267, ABT-333|DRUG: Ribavirin|DRUG: Placebo for ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Modakafusp Alfa in Adult Participants With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Modakafusp alfa|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Carfilzomib|DRUG: Daratumumab|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-induced Adipose Tissue Cavitation and Training in Obesity
Status: TERMINATED
Conditions: Obesity
Interventions: OTHER: Exercise training intervention with ultrasound induced adipose tissue cavitation|OTHER: Exercise training intervention without ultrasound induced adipose tissue cavitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stereotactic Body Radio Therapy (SBRT) for Early-stage Non Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: SBRT by cyberknife|RADIATION: SBRT by linear accelerator|RADIATION: Conformational radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarilumab on Atherosclerotic Disease Assessed by PET/CET in Patients With RA (SARIPET)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Atherosclerosis
Interventions: DRUG: Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Examing The Effect of Grapefruit Juice On The Blood And Urine Samples of Study Drug And Its By Product And Safety
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: CP-945,598|DRUG: CP-945,598
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MB07803|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Radiolabeled OTSA101-DTPA in Patients With Relapsed or Refractory Synovial Sarcoma
Status: TERMINATED
Conditions: Relapsed or Refractory Synovial Sarcoma
Interventions: DRUG: OTSA101-DTPA-111In|DRUG: OTSA101-DTPA-90Y
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Trial of Newborn Skin and Umbilical Cord Cleansing on Neonatal Mortality in Nepal
Status: COMPLETED
Conditions: Neonatal Mortality
Interventions: BEHAVIORAL: Newborn skin cleansing with 0.25% chlorhexidine solution|BEHAVIORAL: Cleansing of umbilical cord with soap and water solution|BEHAVIORAL: Cleansing of umbilical cord with 4% chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Accuracy of an Integrated Vital Sign Measurement Platform
Status: COMPLETED
Conditions: Multimorbidity
Interventions: OTHER: Vital Moto Mod|OTHER: Welch Allyn Connex Spot Vital Signs Monitor|OTHER: Capnostream 20 Portable Bedside Capnograph|OTHER: Welch Allyn 767 Mobile Aneroid Sphygmomanometerand 3M Littmann Master Classic II Teaching Stethoscope|OTHER: Scifit 1000R cycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Guided Bone Regeneration in Atrophic Anterior Maxillary Ridges
Status: UNKNOWN
Conditions: Bone Resorption Disorder
Interventions: PROCEDURE: GBR by xenograft and autogenous bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reduced Intensity Conditioning Transplantation Versus Standard of Care in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Reduced Intensity Conditioning Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Therapy With Narrow-Band Ultraviolet B Phototherapy and Apremilast for the Treatment of Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Apremilast|PROCEDURE: NB-UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artemether-Lumefantrine (AL) Unit Dose Pre-packs Versus Blister Packs
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: AL Blister-packs with Instruction leaflets|DRUG: AL unit dose age specific pre-packs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-operative Forearm Exercises on Arterial Venous Fistula Maturation and Blood Flow
Status: UNKNOWN
Conditions: End Stage Renal Disease|Arteriovenous Fistula
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Development of a Domestic Violence Perpetrator Collusion Measurement Tool
Status: COMPLETED
Conditions: Intimate Partner Violence (IPV)
Interventions: OTHER: Condition 1: Perpetrator Positive|OTHER: Condition 2: Perpetrator Negative|OTHER: Condition 3: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study of Melphalan and Topotecan (MT) Followed by Autologous Stem Cell Rescue in Patients With Multiple Myeloma.
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: melphalan|DRUG: topotecan (TPT)|PROCEDURE: Autologous Stem Cell Rescue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: McGrath vs. C-MAC Video Laryngoscopy Comparison in Endotracheal Tube Insertion
Status: COMPLETED
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Behavioral and Physiological Effects of THC and CBD
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: Vaporized THC alone|DRUG: Vaporized CBD alone|DRUG: Vaporized CBD with THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FX-322 in Adults With Stable Sensorineural Hearing Loss
Status: COMPLETED
Conditions: Sensorineural Hearing Loss|Noise Induced Hearing Loss|Sudden Sensorineural Hearing Loss
Interventions: DRUG: FX-322 (One Dose)|DRUG: FX-322 (Two Doses)|DRUG: FX-322 (Four Doses)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study
Status: UNKNOWN
Conditions: Dental Caries|Early Childhood Caries
Interventions: OTHER: Dental care, AG, MI & fluoride varnish|OTHER: Delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cord Blood Expansion on Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Leukemia
Interventions: PROCEDURE: Cord Blood Infusion|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Rituximab|OTHER: ATG|DRUG: Cyclophosphamide|DRUG: Clofarabine|RADIATION: Total Body Irradiation (TBI)|DRUG: Melphalan|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic NT-proBNP and ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm, Sweden - STROKESTOP II
Status: UNKNOWN
Conditions: Atrial Fibrillation|Stroke
Interventions: OTHER: ECG screening (Zenicor-ECG) for atrial fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Density, Low|Bone Loss|Anorexia Nervosa|Eating Disorders
Interventions: DRUG: Romosozumab Prefilled Syringe|DRUG: Placebo|DRUG: Alendronate 70Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Pathways Leading to Fatty Liver and Atherogenic Dyslipidemia
Status: ENROLLING_BY_INVITATION
Conditions: Non-alcoholic Fatty Liver|Atherogenic Dyslipidemia|Insulin Resistance
Interventions: DIAGNOSTIC_TEST: Lipoprotein kinetics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beginning a Randomized Evaluation of the AGE Breaker Alagebrium in Diastolic Heart Failure (BREAK-DHF-I)
Status: TERMINATED
Conditions: Diastolic Heart Failure
Interventions: DRUG: alagebrium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption and Transfer to the Fetus During Pregnancy in Normal Weight and Overweight/Obese Women and the Effects on Infants Iron Status
Status: COMPLETED
Conditions: Overweight|Obesity|Pregnancy
Interventions: OTHER: Stable iron isotope 57 (57Fe) labeled iron solution|OTHER: Stable iron isotope 58 (58Fe) labeled iron solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mapping Draining Lymph Nodes in CNS Malignancies
Status: TERMINATED
Conditions: Central Nervous System Neoplasms|Central Nervous System Tumor
Interventions: DRUG: Tc-99m tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects
Status: COMPLETED
Conditions: Hyperglycemia, Postprandial
Interventions: DIETARY_SUPPLEMENT: Verum T1|DIETARY_SUPPLEMENT: Verum T2|DIETARY_SUPPLEMENT: Verum T3|DIETARY_SUPPLEMENT: Verum T4|DIETARY_SUPPLEMENT: Verum T5|DIETARY_SUPPLEMENT: Verum T6|DIETARY_SUPPLEMENT: Verum T7|DIETARY_SUPPLEMENT: Verum T8|DIETARY_SUPPLEMENT: Verum T9|DIETARY_SUPPLEMENT: Verum T10|DIETARY_SUPPLEMENT: Verum T11|DIETARY_SUPPLEMENT: Verum T12|DIETARY_SUPPLEMENT: Verum T13|DIETARY_SUPPLEMENT: Verum T14|DIETARY_SUPPLEMENT: Verum T15|DIETARY_SUPPLEMENT: Verum T16|DIETARY_SUPPLEMENT: Verum T17
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression
Status: ACTIVE_NOT_RECRUITING
Conditions: Age Related Macular Degeneration|Intermediate AMD|Atrophy|Prediction
Interventions: DIAGNOSTIC_TEST: Collection of both retrospective and prospective data collection in 3 visits.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion
Status: COMPLETED
Conditions: Chin Retrusion|Chin Augmentation
Interventions: DEVICE: Restylane Defyne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Massage of the Thoracic Region in Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Neck pain massage|OTHER: Neck and thoracic massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Jumbo and Hot Biopsy Forceps
Status: COMPLETED
Conditions: Colonoscopy|Polypectomy
Interventions: DEVICE: Jumbo forceps|DEVICE: Hot biopsy forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of VI-0521 Compared to Placebo in Treatment of Obesity in Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: VI-0521|DRUG: VI-0521|DRUG: Placebo matched phentermine/topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Safety and Performance of Microwave Coagulation Using the HS1 Instrument
Status: UNKNOWN
Conditions: Actual or Potential Nonvariceal Bleeding in the Upper Gastrointestinal (GI) Tract
Interventions: DEVICE: Microwave coagulation using HS1 Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Lumbar Erector Spinae Plane Block Versus Caudal Block for Postoperative Analgesia in Hip and Proximal Femur Surgery in Pediatric Patients
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: erector spinea block|PROCEDURE: Caudal epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NLP Headache Speech (NLPH-SPEECH): a Cross-sectional Study on Natural Language Processing Analysing Spoken Monologues by Headache Patients
Status: COMPLETED
Conditions: Headache Disorders
Interventions: OTHER: Digital Analysis of Speech
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes
Status: COMPLETED
Conditions: Spleen-Preserving Surgery|Echinococcus Granulosus Infection|Hydatid Disease|Minimally Invasive Surgery
Interventions: PROCEDURE: Minimally Invasive Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma, Neovascular
Interventions: DRUG: Aflibercept (Eylea, BAY 86-5321)|DRUG: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients
Status: RECRUITING
Conditions: Postoperative Cognitive Dysfunction
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of a Single Injection of SCH 900962 Versus Daily recFSH Injections in Women Undergoing Controlled Ovarian Stimulation (Study P06029)
Status: COMPLETED
Conditions: Infertility
Interventions: BIOLOGICAL: SCH 900962 / Corifollitropin alfa / Org 36286|BIOLOGICAL: RecFSH / follitropin beta|DRUG: Placebo for SCH 900962|DRUG: Placebo for recFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Outcomes and Patient Satisfaction With Vivity IOL in Post Refractive Patients
Status: RECRUITING
Conditions: Pseudophakia
Interventions: DIAGNOSTIC_TEST: Visual Acuity|DIAGNOSTIC_TEST: Defocus Curve|OTHER: Intraocular Lens Satisfaction (IOLSAT) Questionnaire|OTHER: Quality of Vision After Surgery (QUVID) Questionnaire|OTHER: Visual Disturbance Questionnaire|DIAGNOSTIC_TEST: Topography and Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: MGMT-Unmethylated Glioblastoma
Interventions: DRUG: Etoposide Plus Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Three Different Techniques During PIVC
Status: NOT_YET_RECRUITING
Conditions: Pain|Arm|Visual Aura|Infrared; Rays, Injury
Interventions: OTHER: Experimental group: infrared vascular imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of an Aluvia-based HAART Regimen for Prevention of Mother-to-child HIV Transmission in Africa
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lopinavir/Ritonavir (200/50 mg) Tablets + Zidovudine + 3TC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Glivec in Patients With Tumor Cells Positive for C-kit or PDGFR; a Multi Center Study.
Status: WITHDRAWN
Conditions: Metastatic Solid Tumors.
Interventions: DRUG: Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxycodone hydrochloride tablet 30 mg|DRUG: Roxicodone™ tablet 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Guaraná for Radiation Related Fatigue in Breast Cancer Patients
Status: COMPLETED
Conditions: Fatigue
Interventions: DRUG: Guaraná|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)
Status: RECRUITING
Conditions: Geographic Atrophy
Interventions: DRUG: ANX007|OTHER: Sham Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ozanimod in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Ozanimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Azzalure/Dysport, Restylane/Emervel Filler and Restylane Skinbooster Treatment
Status: COMPLETED
Conditions: Aesthetics
Interventions: DRUG: Azzalure or Dysport|DEVICE: Restylane or Emervel filler|DEVICE: Restylane Skinbooster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of South Beach Diet (SBD™) Using SBD™ Products Compared to a Calorie-Restricted Diet in Women
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: South Beach Diet™ with South Beach Diet™ Products|BEHAVIORAL: South Beach Diet™|BEHAVIORAL: Calorie restricted diet with South Beach Diet™ Products|BEHAVIORAL: Calorie Restricted Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection
Status: UNKNOWN
Conditions: HIV
Interventions: DRUG: efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Anterior Stabilization With Transsubscapular Long Head of the Biceps
Status: COMPLETED
Conditions: Anterior Shoulder Dislocation|Bankart Lesion|Hill Sachs Lesion
Interventions: PROCEDURE: Dynamic Anterior Stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study
Status: TERMINATED
Conditions: Keratosis Pilaris
Interventions: DRUG: Salkera Emollient Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Strontium Ranelate in Proximal Femur Fragility Fractures.
Status: RECRUITING
Conditions: Fragility Fracture|Femur; Fracture, Pertrochanteric|Clinical Trial
Interventions: DRUG: Strontium Ranelate|DRUG: Lacto-N-Hexaose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Training for Non-Specialist Health Workers to Deliver a Brief Psychological Treatment for Depression
Status: COMPLETED
Conditions: Depression|Mental Disorder|Psychological
Interventions: OTHER: Face-to-Face Training|OTHER: Digital Training|OTHER: Coaching Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Corheart 6 Left Ventricular Assist System Prospective, Multicenter, Single-arm Clinical Evaluation Trial
Status: COMPLETED
Conditions: End-stage Heart Failure
Interventions: DEVICE: Corheart 6 Left Ventricular Assist System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Markers of Neurodegenerative Disorders at Presymptomatic Stages
Status: NOT_YET_RECRUITING
Conditions: Neurodegenerative Diseases
Interventions: RADIATION: PET|OTHER: MRI 3T|OTHER: Oculomotricity assessment|OTHER: Magnetoencephalography assessment|OTHER: Body posture and gait assessment|OTHER: Voice recording|OTHER: Video-polysomnography|BIOLOGICAL: Blood sampling, skin biopsy, excreta sampling, lumbar puncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: B-type Natriuretic Peptide in the Diagnosis of Heart Failure Related Ascites
Status: COMPLETED
Conditions: Heart Failure|Liver Cirrhosis|Ascites|Carcinomatosis
Interventions: PROCEDURE: BNP, SAAG, ascites total protein, echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Ibrutinib in Combination With Rituximab-CHOP in Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: vincristine|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Influence of a Core Muscle Control-Based Rehabilitation Program Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Pelvic Floor Disorders|Incontinence, Urinary
Interventions: OTHER: rehabilitation programme based on motor control of core muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease
Interventions: OTHER: Placebo|BIOLOGICAL: Bepranemab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CART-meso in Mesothelin Expressing Cancers
Status: COMPLETED
Conditions: Metastatic Pancreatic (Ductal) Adenocarcinoma|Epithelial Ovarian Cancer|Malignant Epithelial Pleural Mesothelioma
Interventions: BIOLOGICAL: CART-meso
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Mentored Approaches For Men And Women With Coronary Artery Disease ("4Steps")
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Peer Mentor|BEHAVIORAL: Transcendental Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Arsenic Trioxide With Cyclophosphamide in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Relapsed/Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cyclophosphamide 500 MG|DRUG: Cyclophosphamide 1000 MG|DRUG: Cyclophosphamide 2000 MG|DRUG: Cyclophosphamide 3000 MG|DRUG: Cyclophosphamide 4000 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ability of Pupillometry to Reduce Sufentanil Consumption in Planned Cardiac Surgery: Randomized, Controlled, Single-center Clinical Superiority Trial
Status: COMPLETED
Conditions: Patients Undergoing Cardiac Surgery|Patients With Coronary Artery Bypass Surgery With CEC
Interventions: DRUG: Induction and maintenance of anesthesia|DRUG: Adaptation of sufentanil doses according to the usual protocol|DRUG: Adjustment of sufentanil doses according to pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Remote Ischemic Preconditioning in Patients Undergoing Isolated Aortic Valve Replacement Surgery
Status: TERMINATED
Conditions: Aortic Valve Disease|Myocardial Ischemia
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder Surgery
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: DRUG: Tramadol|DRUG: Paracetamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Safety Study of Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Human spinal cord stem cell implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine Combined With Standard Triple Region for Eradication of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: standard triple region|DRUG: 2-week Xiang-sha-liu-jun decoction|DRUG: 4-week Xiang-sha-liu-jun decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm Infants
Status: TERMINATED
Conditions: Hyaline Membrane Disease
Interventions: OTHER: Minimally invasive endotracheal surfactant application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: GABAergic Modulation in Pain Transmission in Human: Effect of the GABAA Agonist Clobazam on Peripheral and Central Sensitisation
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Clonazepam|DRUG: Tolterodine|DRUG: clobazam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Placebo (sugar pill)|DRUG: Topiramate|DRUG: Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Emergency Management of Status Epilepticus
Status: RECRUITING
Conditions: Status Epilepticus
Interventions: OTHER: Pre-briefing with the current SE treatment guidelines|OTHER: Pre-briefing with a consolidated "one page" SE treatment guide|OTHER: No Pre-briefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a Smart Phone App-based Case Management Model Among ART-naive HIV-infected MSM
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: APP-based case management service|BEHAVIORAL: Standard-of-care followup service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Skyvaricella Injection in Healthy Volunteer Vietnamese Children From 12 Months to 12 Years Old
Status: COMPLETED
Conditions: Chickenpox
Interventions: BIOLOGICAL: Skyvaricella Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis
Status: RECRUITING
Conditions: Systemic Amyloidosis
Interventions: DRUG: 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m.|DRUG: 99mTc-Pyrophosphate and 99mtc-p5+14 - an Amyloid Reactive Peptide Labeled With Technetium-99m.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Oral Oteseconazole (VT-1161) for Acute Yeast Infections in Patients With Recurrent Yeast Infections
Status: COMPLETED
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: Oteseconazole (VT-1161) 150mg capsule|DRUG: Fluconazole 150mg capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Steroid Refractory Graft Versus Host Disease
Interventions: OTHER: Cellular Therapy|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Small Cell Lung Cancer
Interventions: DRUG: Tarlatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Tolerability, and Efficacy of Dexmecamylamine (TC-5214) for Treatment of Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: dexmecamylamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In-stent Repair and Vessel Reaction of STEMI Patients With OCT
Status: UNKNOWN
Conditions: Drug-eluting Stents|Percutaneous Coronary Intervention|Optical Coherence Tomography|ST-Elevation Myocardial Infarction
Interventions: PROCEDURE: percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Relative Bioavailability of Mosapride 5mg From Two Candidate Formulations of GR107719B Relative to One 5mg Tablet of Reference Mosapride Citrate (GASMOTIN™) in Healthy Adult Human Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Gastritis
Interventions: DRUG: Reference mosapride citrate (GASMOTIN)|DRUG: GR107719B (Formulation 1)|DRUG: GR107719B (Formulation 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Portfolio Diet on NAFLD in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Type 2|NAFLD
Interventions: OTHER: Portfolio Diet|OTHER: MUFA Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Back Pain With Focused Vibroacoustic Stimulation
Status: UNKNOWN
Conditions: Back Pain
Interventions: DEVICE: KKT|DEVICE: sham KKT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) on Predictive Values of RVR on Sustained Virological Response in Different Stages of Liver Fibrosis in Treatment-Naïve Patients With Chronic Hepatitis C Genotype 1
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing the Effects of the Caregiver Interaction Profile Training on the Interactive Skills of Daycare Providers
Status: RECRUITING
Conditions: Healthy|Emotion Regulation|Language Development|Interactive Skills Daycare Providers
Interventions: BEHAVIORAL: Caregiver Interaction Profile (CIP) training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Intravitreal Bevacizumab in Patients With Diffuse Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetes Mellitus Type 2|Diabetic Macular Edema
Interventions: DRUG: Intravitreal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epinephrine Versus Isoprenaline During Out-of-Hospital Cardiac Arrest With Asystole
Status: NOT_YET_RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DRUG: Isoprenaline Only Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bemiparin Versus Enoxaparin in the Treatment of DVT
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: Bemiparin sodium|DRUG: Enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Validate Novel Seizure-Detection Algorithm
Status: UNKNOWN
Conditions: Seizures, Motor|Seizures|Seizure Disorder|Epilepsy|Epileptic Seizures|Epileptic
Interventions: DEVICE: Motor Seizure Detection Algorithm (mSDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Combination With Cisplatin, Vinblastine, and Temozolomide in Treating Patients With Recurrent or Metastatic Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Skin Melanoma
Interventions: DRUG: Cisplatin|DRUG: Gamma-Secretase Inhibitor RO4929097|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temozolomide|DRUG: Vinblastine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FARD (RaDiCo Cohort) (RaDiCo-FARD)
Status: RECRUITING
Conditions: Inherited Epidermolysis Bullosa|Ichthyosis|Ectodermal Dysplasia|Incontinentia Pigmenti|Neurofibromatosis Type 1|Albinism|Pemphigus|Mucous Membrane Pemphigoid|Palmoplantar Keratoderma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MARPE in Patients With Cleft Lip and Palate
Status: UNKNOWN
Conditions: Palatal Expansion Technique|Cleft Lip and Palate|Class III Malocclusion|Skeletal Malocclusion
Interventions: DEVICE: Rapid maxillary expansion|DEVICE: Maxillary Protraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
Status: NOT_YET_RECRUITING
Conditions: Roux-en-y Anastomosis Site|Marginal Ulcer|Marginal Ulcer (Peptic) or Erosion|Ulcer|Ulcer, Gastric|Ulcer Gastrointestinal|Abdominal Pain|Nausea|Vomiting|GastroIntestinal Bleeding|Dysphagia|Ulcer Gastrojejunal
Interventions: PROCEDURE: Low Thermal Plasma (LTP) Treatment|OTHER: Standard of Care Ulcer Treatment (typically PPI Administration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Inhibition (EI): A Preliminary Study To Inhibit Preterm Labor And Preterm Birth
Status: WITHDRAWN
Conditions: Premature Birth|Premature Labor
Interventions: DEVICE: Electrical Inhibition (EI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Trial of Vemurafenib and Hydroxychloroquine in Patients With Advanced BRAF Mutant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Hydroxychloroquine (HCQ)|DRUG: Vemurafenib (VEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
Status: COMPLETED
Conditions: HPV Infections|Cervical Cancer|Vulvar Cancer|Vaginal Cancer|CIN1|CIN2|CIN3|VaIN1|VaIN2|VaIN3|Genital Wart|VIN 1|VIN 2|VIN 3|AIS
Interventions: BIOLOGICAL: Experimental: Experimental: 9-valent Human Papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52, 58)|BIOLOGICAL: Active Comparator: GARDASIL ®9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Outcomes in Foot and Ankle Bone Grafting Using map3® Cellular Allogeneic Bone Graft
Status: TERMINATED
Conditions: Foot Deformities, Acquired|Disorder of Joint of Foot|Fracture of Foot|Deformity of Bone
Interventions: DEVICE: map3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monotherapy Study in Patients With Type 2 Diabetes Mellitus (0431-021)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin (MK0431)|DRUG: Sitagliptin|DRUG: Placebo|DRUG: Placebo|DRUG: Metformin - Rescue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Resuscitation in Early Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Sepsis|Severe Sepsis
Interventions: DRUG: 5% albumin|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Safety, Tolerability, Feasibility and Pharmacokinetics of Intrath. Administered ATI355 in Patients With Acute SCI
Status: COMPLETED
Conditions: Acute Spinal Cord Injury
Interventions: DRUG: ATI355
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution
Status: COMPLETED
Conditions: Opioid Substitution Treatment
Interventions: DRUG: MR902|DRUG: IR morphine sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carcinoid Heart Disease and Peptide Receptor Radiotargetted Therapy
Status: NOT_YET_RECRUITING
Conditions: Carcinoid Heart Disease|Carcinoid Syndrome|Carcinoid Tumor
Interventions: DRUG: Lutathera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Effect of Raised Supine Position and Back Support on Back Pain, Anxiety and Comfort Level in Coronary Angiography Patients
Status: COMPLETED
Conditions: Coronary Angiography Patient|Anxiety|Back Pain|Comfort
Interventions: OTHER: Determination of the Effect of Raised Supine Position and Back Support on Back Pain, Anxiety and Comfort Level in Coronary Angiography Patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy of Raltegravir (Isentress®), Administered in Combination With Other Antiretroviral Drugs as Treatment for Adults and Older Adults Infected With the Human Immunodeficiency Virus 1 (HIV-1)(MK-0518-145) (Wirksamkeit Von Isentress® Unter Praxisbedingungen)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Raltegravir|DRUG: Raltegravir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of Nivolumab in Solid Tumors Induced by Prior Radiation Exposure
Status: TERMINATED
Conditions: Solid Tumors Induced by Prior Radiation Exposure
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MBCT and CBT for Depression in Patients After Cancer: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy (MBCT)|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT