pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Induction of Labor in Women With Unfavorable Cervix: Dilapan Versus Foley Bulb
Status: COMPLETED
Conditions: Pre-induction Dilation of Cervix
Interventions: DEVICE: Dilapan|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Radiation Therapy in Treating Patients With Previously Untreated Thyroid Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: fluorouracil|DRUG: hydroxyurea|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Development of a Digital Tool, MyInspiration, for the Improvement of Spiritual Well-Being in Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: OTHER: Internet-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis|Cystic Fibrosis
Interventions: DRUG: alendronate sodium|DRUG: calcium carbonate|DRUG: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/Disorders
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Fanconi Anemia|Aplastic Anemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: graft-versus-tumor induction therapy|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methylprednisolone|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prevalence of Oculomotor Disorders in Patients With Radiologically Isolated Syndrome
Status: COMPLETED
Conditions: Radiologically Isolated Syndrome (RIS)|Multiple Sclerosis
Interventions: OTHER: Neurological consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Precise Endoscopic Application of Tranexamic Acid and Sucralfate in Gastrointestinal Bleeding: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Bleed Ulcer
Interventions: DRUG: Tranexamic Acid Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: GTU®-MultiHIV B Clade Vaccine|OTHER: Sodium chloride BP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Covered Self-expandable Metallic Stents Insertion Using Clips and Suture Materials for Preventing Migration
Status: COMPLETED
Conditions: Gastroduodenal Anastomosis
Interventions: PROCEDURE: deployment of through the scope covered metallic stent at the stricture site|DEVICE: Covered Self-expandable Metallic Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproductive Life Planning for Women With Mental Illness
Status: COMPLETED
Conditions: Psychotic Disorders|Mood Disorders|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Reproductive Life Planning-Mental Health (RLP-MH) Intervention|OTHER: Written Materials on Reproductive Life Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heterologous Boost Immunization With an Aerosolised Ad5-nCoV After Two-dose Priming With an Inactivated SARS-CoV-2 Vaccine
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Aerosolized Ad5-nCoV|BIOLOGICAL: Inactivated SARS-CoV-2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Placebo|DRUG: St. Johns Wort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Towards HOMe-based Albuminuria Screening: an Implementation Study Testing Two Approaches
Status: UNKNOWN
Conditions: Albuminuria
Interventions: DIAGNOSTIC_TEST: Approach A (PeeSpot urine collection device).|DIAGNOSTIC_TEST: Approach B (ACR | EU Test kit).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of HPIPC for the Treatment of Ischemic Ulcers in Subjects With PAD
Status: COMPLETED
Conditions: PVD|Arterial Ulcers
Interventions: DEVICE: High pressure intermittent pneumatic compression (HPIPC)|BEHAVIORAL: Excercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Spinal Morphine After Caesarean Section : A Comparison Study
Status: COMPLETED
Conditions: Pregnancy, Ceasarian Section, Anaesthesia
Interventions: DRUG: Intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Inflammation With 18F-PBR06 to Identify Unstable Carotid Plaques in Patients With Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: 18F-PBR06
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MSLN-targeted CAR-T Cells in Solid Tumors.
Status: NOT_YET_RECRUITING
Conditions: Mesothelin-positive Advanced Malignant Solid Tumors
Interventions: BIOLOGICAL: Anti-mesothelin CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Steroid Resistant and Steroid Dependent Gut Acute Graft Versus Host Disease
Status: UNKNOWN
Conditions: Stem Cell Transplant Complications|Graft Versus Host Disease, Acute|Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seasonal Trivalent Inactivated Split Virion Influenza Vaccine Clinical Trial (IVACFLU-S)
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Trivalent Seasonal Influenza Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Mycophenolate Mofetil in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of Isavuconazole|Pharmacokinetics of Plasma Mycophenolic Acid (MPA)|Pharmacokinetics of Plasma Phenolic Glucuronide of MPA (MPAG)
Interventions: DRUG: isavuconazole|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.
Status: COMPLETED
Conditions: Urologic Diseases
Interventions: PROCEDURE: warming during induction of anesthesia|PROCEDURE: Prewarmed intravenous fluid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cost-effectiveness of Screening for Diabetic Retinopathy in Hong Kong
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: OTHER: charging a co-payment for Diabetic Retinopathy screening|OTHER: free screening without charging a co-payment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Treatment Response in Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Lymphedema of Upper Limb|Breast Cancer|Breast Cancer Lymphedema
Interventions: PROCEDURE: Complete Decongtestive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Stress Reduction in Caregivers of Children With ASD Using ACT
Status: RECRUITING
Conditions: Caregiver Stress
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Caregiver Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral and Pharmacological Reconsolidation Interference in Misophonia
Status: ENROLLING_BY_INVITATION
Conditions: Misophonia
Interventions: DRUG: Propranolol Hydrochloride tablet|BEHAVIORAL: Reminder|BEHAVIORAL: Counterconditioning|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Breast Adenocarcinoma|Breast Ductal Carcinoma In Situ|Estrogen Receptor-Positive Breast Carcinoma|Progesterone Receptor-Positive Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: BRC-001|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of I-131-1095 Radiotherapy in Combination With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer Who Are Chemotherapy Naive and Have Progressed on Abiraterone
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Castration-resistant Prostate Cancer|Prostatic Neoplasm|Cancer of the Prostate|Progressive mCRPC
Interventions: DRUG: I-131-1095|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Triclosan-coated Suture on Superficial SSI
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Triclosan coated suture|PROCEDURE: No triclosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Genotype on Resting State Connectivity During Methamphetamine Administration
Status: COMPLETED
Conditions: Methamphetamine-dependence
Interventions: BEHAVIORAL: Magnetic resonance imaging (MRI)|DRUG: Methamphetamine Hydrochloride Tablets|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: clofarabine (IV formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Doxapram Versus Theophylline on Diaphragmatic Function
Status: UNKNOWN
Conditions: Weaning Failure
Interventions: DRUG: Doxapram Hydrochloride|DRUG: Theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Yangxinshi Tablet on Exercise Tolerance in Patients With Chronic Coronary Syndrome（MET STUDY）
Status: RECRUITING
Conditions: Chronic Coronary Syndrome
Interventions: DRUG: Yangxinshi tablet|DRUG: Yangxinshi tablet simulants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of an H5N1 VLP
Status: COMPLETED
Conditions: Pandemic Influenza
Interventions: BIOLOGICAL: H5N1 VLP Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Explore the Safety And Tolerability of Doses of E2007 Up to a Maximum of 8 mg In Patients With Parkinson's Disease Who Experience End-of-Dose Wearing Off Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: E2007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
Status: COMPLETED
Conditions: Complex Regional Pain Syndromes|Postherpetic Neuralgia|Phantom Limb Pain|Chronic Post Surgical Pain|Post-Traumatic Neuralgia|Neuropathic Pain
Interventions: PROCEDURE: US-SGB|PROCEDURE: US-TPVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Natural Killer Cells in Human Skin
Status: COMPLETED
Conditions: Atopic Dermatitis|Contact Dermatitis|Psoriasis|Lichen Planus|Graft Versus Host Disease|Melanoma
Interventions: OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood|OTHER: Biopsy and sample of blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Analgesic Control Following Knee Arthroscopy
Status: COMPLETED
Conditions: Knee|Arthroscopy|Analgesia
Interventions: PROCEDURE: Intraarticular injection|PROCEDURE: Intra-articular injection of 0.5% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OnabotulinumtoxinA (BOTOX®) Treatment for Urinary Incontinence in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: BIOLOGICAL: onabotulinumtoxinA|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Rhus Coriaria L. on Body Weight
Status: COMPLETED
Conditions: Body Weight
Interventions: DRUG: Rhus Coriaria L.(Rhus)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CO2 Absorption During Laparoscopy
Status: COMPLETED
Conditions: Pneumoperitoneum
Interventions: PROCEDURE: alteration of the insufflation gas|PROCEDURE: full conditioning|PROCEDURE: standard pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pregabalin add-on for Neuropathic Pain in Cervical Myelopathy
Status: UNKNOWN
Conditions: Pain, Neuropathic
Interventions: DRUG: Pregabalin|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Primary Objective of This Study is to Determine Whether MICARDIS® Improves Insulin Sensitivity in Overweight or Obese, Non-diabetic, Normotensive Subjects
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: MICARDIS® (telmisartan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Pre Diabetes|High Blood Pressure|Elevated LDL Cholesterol
Interventions: OTHER: Exercise Time|BEHAVIORAL: Supervised Group Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Diagnostic Ability of White Light Endoscopy and Magnifying Endoscopy With Optical Enhancement System
Status: UNKNOWN
Conditions: Early Gastric Cancer
Interventions: DEVICE: magnifying endoscopy with optical enhancement system|DEVICE: white light endoscopy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of Altabax to Clear Methicillin-resistant Staphylococcus Aureus (MRSA) Nasal Colonization
Status: WITHDRAWN
Conditions: Methicillin-resistant Staphylococcus Aureus
Interventions: DRUG: Retapamulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults
Status: COMPLETED
Conditions: Overactive Bladder|Urge Incontinence|Nocturia
Interventions: OTHER: Transcutaneous tibial nerve stimulation along with pelvic floor muscle srengthening|OTHER: Pelvic floor muscles strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOUR-SIX TRIAL for the Treatment of Enterococcal Endocarditis
Status: NOT_YET_RECRUITING
Conditions: Enterococcal Endocarditis
Interventions: DRUG: 4-week duration of antibiotic therapy|DRUG: 6-week duration of antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure Patients
Status: RECRUITING
Conditions: Liver Cirrhosis|Acute on Chronic Liver Failure
Interventions: DIAGNOSTIC_TEST: Relaxed Rotational Thromboelastometry|DIAGNOSTIC_TEST: Standard Coagulation Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Inorganic Nitrate and the Enteral Microbiome
Status: RECRUITING
Conditions: Cardiovascular Health
Interventions: DIETARY_SUPPLEMENT: Nitrate|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Treatment Regimens Using Ranibizumab: Intensive (Resolution of Intra- and Sub-retinal Fluid) vs Relaxed (Resolution of Intra-retinal Fluid and/or Sub-retinal Fluid >200µm at the Foveal Centre)
Status: COMPLETED
Conditions: Subfoveal Choroidal Neovascularization CNV Secondary to Wet Age-related Macular Degeneration AMD
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Delivery of JNJ-54767414 (Daratumumab) in Japanese Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: DARA SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.
Status: RECRUITING
Conditions: Educational Problems
Interventions: OTHER: Biplane Ultrasound|OTHER: Single plane ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Early Postmenopausal Bone Loss With Lactobacillus Reuteri
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri ATCC PTA 6475 (L. reuteri 6475)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of a Novel, Fully Remote Counseling and Sound Therapy Program for Hyperacusis
Status: RECRUITING
Conditions: Hyperacusis
Interventions: DEVICE: Sound therapy using low-level background sound|BEHAVIORAL: Remote counseling using HAT-Online|OTHER: Sound therapy using successive approximations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Resistant Starch in COVID-19 Infection
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Dietary Supplement containing resistant starch|DIETARY_SUPPLEMENT: Placebo Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Inotuzumab Ozogamicin + Temsirolimus in Patients With Relapsed or Refractory CD22+ B-cell NHLymphoma
Status: COMPLETED
Conditions: B-cell Lymphoma Refractory
Interventions: DRUG: Inotuzumab Ozogamicin|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychobiological Mechanisms of Placebo and Nocebo Effects in the Treatment of Chronic Back Pain
Status: COMPLETED
Conditions: Chronic Lower Back Pain|Healthy Control Subjects
Interventions: OTHER: Administration of a pharmacological placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imatinib Mesylate to Treat Skin Changes in Patients With Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Sclerotic Graft Versus Host Disease|Imatinib Mesylate
Interventions: DRUG: Gleevec, STI571(Imatinib Mesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage III Melanoma
Interventions: DRUG: isolated limb perfusion|DRUG: melphalan|BIOLOGICAL: recombinant tumor necrosis factor family protein|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sarpogrelate HCL 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: BIOLOGICAL: Allogeneic CD19-STAR T cell|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Dosage of Venetoclax in the Fup of AML Patients Treated With Aza + Ven
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Pharmacokinetic sampling|OTHER: Vital status determination|OTHER: Toxicity assessments|DRUG: Venetoclax and azacitidine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP
Status: RECRUITING
Conditions: Non-Specific Chronic Lower Back Pain
Interventions: DEVICE: NexWave|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Wellbeing in Older Adults: The Impact of an Active Aging Education Program in Pakistan
Status: COMPLETED
Conditions: Aging Well|Well Aging|Quality of Life|Well-Being, Psychological
Interventions: BEHAVIORAL: Blended& integrated happy aging active aging program(BIHAAAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Carvedilol vs. Propranolol in Second Prophylaxis of Variceal Bleeding
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension|Varice Bleed|Cirrhosis, Liver
Interventions: DRUG: Carvedilol|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Milk Derived From Mountain-pasture Grazing Cows on Risk Markers of the Metabolic Syndrome Compared to Conventional Danish Milk
Status: COMPLETED
Conditions: Coronary Heart Disease|Type-2 Diabetes
Interventions: DIETARY_SUPPLEMENT: milk fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploration of Microcirculatory Alteration and Endothelial Dysfunction by Adaptive Optics in Multiple Sclerosis
Status: UNKNOWN
Conditions: Sclerosis, Multiple
Interventions: OTHER: Ocular fundus on patient with Multiple Sclerosis|OTHER: Ocular Fundus on voluntary person
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraoperative Protective Mechanical Ventilation in Patients Requiring Emergency Abdominal Surgery
Status: COMPLETED
Conditions: Emergency Abdominal Surgery|Mechanical Ventilation|General Anesthesia|Postoperative Morbidity
Interventions: OTHER: Driving-pressure-guided group|OTHER: Low PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Tape on Oral and Pharangeal Swallowing Phases in Children With Spastic Cerebral Palsy
Status: RECRUITING
Conditions: Dysphagia, Oropharyngeal, Cerebral Palsy
Interventions: OTHER: Kinesio tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intra-Renal Therapy of Diuretic Unresponsive Acute Kidney Injury
Status: WITHDRAWN
Conditions: Kidney Failures, Acute
Interventions: DRUG: Intra-Renal Fenoldopam|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Milk Fat Globule Membrane (MFGM) - Enriched Formula With Reduced Energy and Protein Content on Growth and Development
Status: COMPLETED
Conditions: Infant
Interventions: DIETARY_SUPPLEMENT: Modified formula (MFGM-enriched formula with reduced energy and protein content)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Paracetamol|DRUG: No Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Use of Azithromycin in Patients With Symptomatic Disseminated Mycobacterium Avium-Intracellulare Complex (MAC) Infection Failing Current Therapy
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distraction and Vibration for Minimizing Pain During Childhood Vaccination
Status: COMPLETED
Conditions: Pain Due to Childhood Vaccination
Interventions: DEVICE: Buzzy specific vibration device|BEHAVIORAL: Distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of Ranquilon Tablets in Patients With Anxiety in Neurasthenia and Adjustment Disorders
Status: COMPLETED
Conditions: Anxiety|Neurasthenia|Adjustment Disorders
Interventions: DRUG: Ranquilon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Matrix Therapy And Bacterial Keratitis
Status: UNKNOWN
Conditions: Bacterial Keratitis
Interventions: DEVICE: RGTA OTR4120 (CACICOL20)|DEVICE: physiological salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravaginal Gel and Ovule Formulations of TOL-463
Status: COMPLETED
Conditions: Vaginal Infection
Interventions: DRUG: TOL-463 Vaginal ovule|DRUG: TOL-463 Vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Adenocarcinoma
Interventions: DEVICE: ctDNA Blood Test|COMBINATION_PRODUCT: FLOT|COMBINATION_PRODUCT: FOLFOX|COMBINATION_PRODUCT: FOLFIRI|COMBINATION_PRODUCT: FOLFIRINOX|COMBINATION_PRODUCT: PACLITAXEL with or without CARBOPLATIN|COMBINATION_PRODUCT: DOCETAXEL and IRINOTECAN (alone or combined)|DRUG: NIVOLUMAB (alone or when added to a regimen above)|DRUG: PEMBROLIZUMAB (alone or when added to a regimen above)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Amniotic Fluid as a Treatment for COVID-19 Patients
Status: COMPLETED
Conditions: SARS CoV-2
Interventions: BIOLOGICAL: Human Amniotic Fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Prostate Disease
Interventions: DRUG: Nivolumab|RADIATION: Brachytherapy|RADIATION: External Beam Radiation Therapy|DRUG: Androgen Deprivation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nasal Spray for Relief of Nasal Congestion in Infants and Toddlers With Common Cold
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DEVICE: Blocked Nose Baby nasal spray|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)|Familiar Hypocalcuric Hypercalcemia|Healthy Volunteers|Type 1 Diabetes Mellitus
Interventions: DEVICE: 1H/ 13C and 31P Magnetic Resonance Spectroscopy|OTHER: Meal Tolerance Test|OTHER: Hyperglycemic-hyperinsulinemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacity and Safety of Tranexamic Acid in Cirrhotic Patients Presenting With Acute Upper Gastrointestinal Bleeding
Status: UNKNOWN
Conditions: Upper Digestive Bleeding|Cirrhosis
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Extended Robotic Right Hemicolectomy With Complete Mesocolic Excision for Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DEVICE: Robot-assisted laparoscopic extended right colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABI v Dry Needling for Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: Autologous Blood Injection|OTHER: Structured rehabilitation programme|OTHER: dry needling injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anesthetics on Troponin I and С-reactive Protein
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Aortic Valve Insufficiency|Cardiac Disease
Interventions: DRUG: Propofol|DRUG: Isoflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
Status: RECRUITING
Conditions: Bladder Cancer|Urocystitis|Urinary Bladder Stone|Urothelial Carcinoma
Interventions: DIAGNOSTIC_TEST: Urine DNA methylation analysis|PROCEDURE: medical imaging and/or cystoscopy and/or pathological examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Of Efficacy And Safety Of Thalidomide Vs Hydroxyurea In Thalassemia Patients: A Single-Centre Pilot Study.
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: DRUG: Thalidomide 100mg|DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Liraglutide in Subjects With Liver Impairment and in Subjects With Normal Liver Function
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POETIG Trial - POnatinib After rEsisTance to Imatinib in GIST
Status: UNKNOWN
Conditions: GIST, Malignant|KIT Exon 13 Mutation|KIT Gene Mutation
Interventions: DRUG: Ponatinib 30 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes)
Status: COMPLETED
Conditions: Alzheimer Disease|Alzheimer Disease, Early Onset|Mild Cognitive Impairment|Memory Loss|Memory Disorders|Memory Impairment
Interventions: OTHER: Biomarker Data Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults
Status: COMPLETED
Conditions: Ketamine-Induced Brain Activity Changes|Psychotic-like Symptoms
Interventions: DRUG: Ketamine|DRUG: TAK-063|DRUG: TAK-063 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FSME IMMUN NEW Follow-up to Study 205 in Children Aged 6 to 16 Years
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Study of Patient Perception and Quality of Life Associated With the Use of Olopatadine 0.2% in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine Hydrochloride Ophthalmic Solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)
Status: NOT_YET_RECRUITING
Conditions: Talaromycosis
Interventions: DRUG: Liposomal Amphotericin B (LAmB)|DRUG: Flucytosine (5FC)|DRUG: Flucytosine (5FC) placebo pill|DRUG: Deoxycholate Amphotericin B (DAmB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Oxygen During CPET in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Oxygen application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Contiguous Stage II Small Lymphocytic Lymphoma|Noncontiguous Stage II Small Lymphocytic Lymphoma|Prolymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage I Small Lymphocytic Lymphoma|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage III Small Lymphocytic Lymphoma|Stage IV Chronic Lymphocytic Leukemia|Stage IV Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: MOR00208|DRUG: lenalidomide|OTHER: Correlative Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peanut-based School Meals in Rural Ghana to Improve Attendance and Retention
Status: ENROLLING_BY_INVITATION
Conditions: School Attendance|School Dropouts|School Enrollment|School Feeding Programs|Child Nutrition
Interventions: DIETARY_SUPPLEMENT: Ready-to-use school food|DIETARY_SUPPLEMENT: Standard meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Usher Syndromes
Interventions: DRUG: NPI-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Contribution of Basketball-specific Target Shooting Exercises to Strength, Position Sense, Stability and Endurance in Young Basketball Players
Status: COMPLETED
Conditions: Open Kinetic Chain Proprioception Exercises
Interventions: OTHER: Open Kinetic Chain Proprioception Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer
Status: TERMINATED
Conditions: Urinary Bladder Cancer
Interventions: DRUG: GemCis + Panitumumab|DRUG: GemCis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SOM230 LAR With Bortezomib and Dexamethasone for Refractory or Relapsed Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma
Interventions: DRUG: SOM230|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts
Status: ACTIVE_NOT_RECRUITING
Conditions: Asymptomatic
Interventions: DIAGNOSTIC_TEST: Contrast-enhanced Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Digital Tomosynthesis Mammography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of OligoG in Cystic Fibrosis Subjects With Burkholderia Spp. Infection
Status: COMPLETED
Conditions: Cystic Fibrosis|Burkholderia Infection
Interventions: DRUG: Alginate oligosaccharide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Nilotinib and Imatinib Combination in Chronic Myeloid Leukemia Patients, With Failure, Suboptimal Response or Treatment Intolerance
Status: COMPLETED
Conditions: Leukemia, Myeloid, Chronic, BCR-ABL Positive
Interventions: DRUG: Imatinib and Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Predictive Markers for Toxicity and Efficacy in Patients With mccRCC Treated by Anti-VEGF Therapy
Status: TERMINATED
Conditions: Clear-cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: patients with sunitinib or pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Sitagliptin in Individuals With Genetically Decreased DPP4
Status: RECRUITING
Conditions: Genetics Disease|Type2 Diabetes|Heart Failure
Interventions: DRUG: Sitagliptin 100mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: High Or Low Dose pOstpartUm Oxytocin at the Time of Cesarean Birth
Status: NOT_YET_RECRUITING
Conditions: Postpartum Hemorrhage|Pregnancy Complications|Cesarean Section Complications
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Crossover Bioequivalence Study of Tinidazole 500 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Trichomoniasis
Interventions: DRUG: Tinidazole|DRUG: Tinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study of HRS2398 in Combination With Adebrelimab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: HRS2398|DRUG: Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide for Prevention of Acute Gastrointestinal GVHD Following Allogenic Stem Cell Transplantation
Status: COMPLETED
Conditions: Leukemia|Graft-Versus-Host Disease
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Trial of ACT-P Versus T4C for Community Reentry
Status: ENROLLING_BY_INVITATION
Conditions: Criminal Behavior|Violence
Interventions: BEHAVIORAL: ACT-P|BEHAVIORAL: T4C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab With Axitinib in Persistent or Recurrent Cervical Cancer After Platinum-based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Avelumab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old
Status: COMPLETED
Conditions: Nasolacrimal Duct Obstruction
Interventions: PROCEDURE: Nasolacrimal balloon catheter duct dilation|PROCEDURE: Nasolacrimal intubation|PROCEDURE: Simple Nasolacrimal duct probing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p