pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Psoriasis Echo Study
Status: RECRUITING
Conditions: Psoriasis|Cardiovascular Diseases|Cardiovascular Risk Factor|Cardiovascular Pathology|Psoriasis Vulgaris|Psoriatic Nail|Psoriasis Face|Psoriasis Guttate|Psoriasis Gyrata|Psoriasis Diffusa|Psoriasis Palmaris|Psoriasis Annularis|Psoriasis Circinata|Psoriasis Plantaris|Psoriasis Universalis|Psoriasis Geographica|Left Ventricular Dysfunction|Myocardial Infarction|Myocardial Ischemia|Heart Failure|Stroke|Heart Diseases|Heart Failure, Systolic|Heart Failure, Diastolic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Performance of ArterX™ Vascular Sealant in Sealing Synthetic Arterial Grafts
Status: COMPLETED
Conditions: Vascular Disease
Interventions: DEVICE: ArterX Vascular Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Clear Cell Renal Cell Carcinoma|Papillary Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: sorafenib tosylate|BIOLOGICAL: recombinant interferon alfa|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea-hypopnea|Oropharyngeal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Lysine|DIETARY_SUPPLEMENT: Controlled Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia
Status: RECRUITING
Conditions: ALL, Childhood B-Cell|Acute Lymphoid Leukemia Relapse|Acute Lymphocytic Leukemia Refractory
Interventions: BIOLOGICAL: Tafasitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of NIC5-15 in the Treatment of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: NIC5-15|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Bapineuzumab 0.5 mg/kg|DRUG: Bapineuzumab 1.0 m/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
Status: RECRUITING
Conditions: Stress|Anxiety
Interventions: BEHAVIORAL: PRISM Program Video Coach|BEHAVIORAL: PRISM Program Text Coach|BEHAVIORAL: mPRISM Program App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Placebo|DRUG: AC-201|DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Exposure Therapy for Post-traumatic Stress Disorder
Status: TERMINATED
Conditions: Chronic Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Revisiting the Trauma memories|BEHAVIORAL: Processing the trauma memories|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Trauma Memory Retrieval Trial|BEHAVIORAL: Exposure to video clips related to the patient's trauma|BEHAVIORAL: Breathing retraining|BEHAVIORAL: Exposure Homework|BEHAVIORAL: Compound extinction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aleglitazar in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Actos|DRUG: Placebo|DRUG: aleglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dosing of Preoperative Gabapentin for Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea, Postoperative|Vomiting, Postoperative|Pain, Postoperative
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer
Status: TERMINATED
Conditions: Bladder Adenocarcinoma|Bladder Mixed Adenocarcinoma|Bladder Squamous Cell Carcinoma|Bladder Urothelial Carcinoma|Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant|Infiltrating Bladder Urothelial Carcinoma With Giant Cells|Infiltrating Bladder Urothelial Carcinoma With Glandular Differentiation|Infiltrating Bladder Urothelial Carcinoma With Trophoblastic Differentiation|Infiltrating Bladder Urothelial Carcinoma, Clear Cell Variant|Infiltrating Bladder Urothelial Carcinoma, Micropapillary Variant|Infiltrating Bladder Urothelial Carcinoma, Nested Variant|Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Cystectomy|DRUG: Doxorubicin|BIOLOGICAL: Durvalumab|DRUG: Gemcitabine|DRUG: Methotrexate|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway
Status: RECRUITING
Conditions: Cholelithiases|Cholecystolithiasis
Interventions: DEVICE: Endotracheal tube (ETT)|DEVICE: ProSeal Laryngeal Mask Airway (PLMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Routine Ultrasound Guidance for Vascular Access for Cardiac Procedures
Status: COMPLETED
Conditions: Myocardial Infarction|Coronary Artery Disease|Myocardial Ischemia
Interventions: PROCEDURE: Fluoroscopic + Ultrasound Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Analysis in Long Term of Radiofrecuency Combined vs. T.E. in the Treatment of Patellofemoral Pain Syndrome.
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Radiofrecuency|OTHER: Therapeutic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: Prevenar|BIOLOGICAL: Tritanrix-HepB|BIOLOGICAL: Hiberix|BIOLOGICAL: Polio Sabin.|BIOLOGICAL: Poliorix.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy
Status: TERMINATED
Conditions: Thyroid Cancer|Postsurgical Hypothyroidism
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Validation of the ADNEX Model for Discrimination Between Benign and Malignant Adnexal Masses in Pregnancy: International Ovarian Tumour Analysis in Pregnancy Study (p-IOTA)
Status: RECRUITING
Conditions: Adnexal Mass|Adnexal Tumor|Adnexal Cyst|Pregnancy Related
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries
Status: COMPLETED
Conditions: Opioid Use|Postoperative Pain
Interventions: PROCEDURE: Postoperative Pain Management Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Fecal Microbiota Transplantation for the Treatment of Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPECT-CT Guided Lymphatic Mapping and Sentinel Lymphadenectomy (LM/SL) in Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: SPECT/CT guided LM/SL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Repository Corticotropin Injection To Treat Rheumatoid Arthritis Patients Who Have Failed Three Biologic Therapies.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Repository corticotropin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP
Status: RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: BIOLOGICAL: rAAV2tYF-GRK1-hRPGRco|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative-care Rehabilitation After Dysvascular Amputation
Status: COMPLETED
Conditions: Diabetes Complications|Peripheral Arterial Disease
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Walking Program|BEHAVIORAL: Health Self-Management Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Endometrial Hyperplasia With a LNG-IUS: Multicenter Study: KGOG2006
Status: UNKNOWN
Conditions: Endometrial Hyperplasia
Interventions: DEVICE: Mirena (LNG-IUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Working Memory Training for HIV Patients
Status: UNKNOWN
Conditions: HIV Infection
Interventions: OTHER: Adaptive WM CogMed Training|OTHER: Nonadaptive WM CogMed Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Intensity Electromagnetic Body Shaping on Profile of Metabolism in Obese Men
Status: RECRUITING
Conditions: Central Obesity
Interventions: DEVICE: high intensity electromagnetic technology device, diet restriction, and walking|BEHAVIORAL: diet restriction and walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Feasibility and Acceptability of a Social Identity Informed Virtual Running Group Program
Status: COMPLETED
Conditions: Well-being|Physical Activity|Identity, Social
Interventions: BEHAVIORAL: Virtual running group program|BEHAVIORAL: Attention Control: Fitness Application Strava
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindfulness- Based Intervention for Systemic Lupus Erythematosus (SLE) Patients
Status: COMPLETED
Conditions: Psychological
Interventions: OTHER: Mindfulness- Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type I
Status: TERMINATED
Conditions: Spinal Muscular Atrophy Type I
Interventions: DRUG: sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Called NATION-OS to Learn About the Link Between N-terminal proBNP (NT-proBNP) Levels and Medical Problems Due to Heart Failure (HF) in German Patients With HF
Status: COMPLETED
Conditions: Heart Failure (HF)
Interventions: OTHER: Decompensation event
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weight Reduction and Cognitive Health: Pilot Study Testing a Prolonged Testing Prolonged Fasting Among Obese, Stressed Mid-life Adults
Status: COMPLETED
Conditions: Midlife Obese Adults With Cognitive Decline
Interventions: BEHAVIORAL: Prolonged nightly fasting|BEHAVIORAL: Health Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Toilet Bronchoscopy in RICU
Status: UNKNOWN
Conditions: COPD|Asthma|Cystic Fibrosis
Interventions: PROCEDURE: toilet bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Positron Emission Tomography(PET) in Lymphoma Assessment
Status: COMPLETED
Conditions: Hodgkin's Lymphoma|Non Hodgkin's Lymphoma
Interventions: BIOLOGICAL: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Utility of Tissue Doppler Echocardiography for Selecting Patients for Cardiac Resynchronisation Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: BiV ICD|DEVICE: ICD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buyuan-zhixiao Formula in the Treatment of Elderly Patients With Diabetes and Multiple Metabolic Disorders
Status: NOT_YET_RECRUITING
Conditions: Diabete Mellitus|Aging|Metabolic Disorders|Traditional Chinese Medicine|Randomized Controlled Trial
Interventions: DRUG: Buyuan Zhixiao Formula|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beer, Marathon, Genetics, Inflammation and the Cardiovascular System: Be-MaGIC-Trial
Status: COMPLETED
Conditions: Inflammation|Heart Failure|Sudden Cardiac Death
Interventions: DIETARY_SUPPLEMENT: polyphenols (non-alcoholic beer)|DIETARY_SUPPLEMENT: beverage without polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients
Status: TERMINATED
Conditions: Epilepsy|Partial Epilepsy
Interventions: DEVICE: Vagal Nerve Simulation (VNS) Therapy|DRUG: Best Medical Practive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nutritional Intervention and Physical Activity Program Reduce Body Weight in Women Newly Diagnosed With Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Body Weight Changes|Weight Loss|Nutrition Related Cancer
Interventions: BEHAVIORAL: Control group|BEHAVIORAL: Nutrition and physical activity group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Remifentanil and Dexmedetomidine in Patients With Noninvasive Mechanical Ventilation Intolerance
Status: UNKNOWN
Conditions: NIV Intolerance
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin Versus Unfractionated Heparin in Subjects Who Present to the Emergency Department With Acute Coronary Syndrome (RESCUE)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of an Intervention to Prevent Acute Kidney Injury Versus Standard Care in High-risk Patients After Major Surgery
Status: RECRUITING
Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: PROCEDURE: Implementation of the KDIGO bundle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid
Status: COMPLETED
Conditions: Gout Chronic|Hyperuricemia
Interventions: DRUG: SEL-212|DRUG: SEL-037|DRUG: SVP-rapamycin (SEL-110)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Autologous T Lymphocytes With ADCC in Patients With CD20-Positive B-Cell Malignancies
Status: UNKNOWN
Conditions: B-Cell Chronic Lymphocytic Leukemia|Non-Hodgkin's Lymphoma
Interventions: DRUG: T-cell therapy + Rituximab + IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Contiguous Stage II Mantle Cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Mantle Cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma|Stage I Mantle Cell Lymphoma|Stage I Mycosis Fungoides/Sezary Syndrome|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma|Stage II Mycosis Fungoides/Sezary Syndrome|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Waldenström Macroglobulinemia
Interventions: DRUG: vorinostat|BIOLOGICAL: rituximab|DRUG: ifosfamide|DRUG: carboplatin|DRUG: etoposide|OTHER: pharmacological study|OTHER: laboratory biomarker analysis|GENETIC: gene expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timolol Gel for Epistaxis in Hereditary Hemorrhagic Telangiectasia
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia
Interventions: DRUG: Timolol Gel|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial for Treatment of Recurrent Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Disease|Recurrent Glioblastoma
Interventions: DRUG: Afatinib|DRUG: Dasatinib|DRUG: Palbociclib|DRUG: Everolimus|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Ursodeoxycholic Acid in Functional Dyspepsia
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Nutridrink|DEVICE: High resolution manometry probe|DEVICE: perfusion catheter|DRUG: Placebo Oral Tablet|DRUG: Ursochol oral tablet|DEVICE: Duodenal fluid aspiration catheter|PROCEDURE: Duodenogastroscopy|PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Patients
Interventions: DRUG: PF-04620110|DRUG: PF-04620110|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Hayfever|Allergy
Interventions: PROCEDURE: Infection with hookworm larvae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Postural Insoles Adapted in Slippers for People With Persistent Heel Pain
Status: COMPLETED
Conditions: Heel Pain Syndrome|Metatarsalgia
Interventions: OTHER: custom slippers with perforated synthetic leather cover.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beraprost Sodium and Arterial Stiffness in Patients With Type 2 Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DRUG: Beraprost sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Alagebrium in Patients With Insulin-Dependent Type 1 Diabetes and Microalbuminuria
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Diabetic Nephropathy
Interventions: DRUG: Alagebrium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Health Intervention on Hypoglycemic Coping : a Pilot Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypoglycemia|Health Education
Interventions: BEHAVIORAL: Impact of an IMB theory-based health education intervention on hypoglycemic coping in patients with type 2 diabetes: a pilot study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internet-based Support for Informal Caregivers of Patients With Head and Neck Cancer - Carer eSupport
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Cancer
Interventions: OTHER: Carer eSupport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Chemotherapy + Surgery Versus Surgery in FIGO IB2 and IIA2 Cervical Cancer
Status: UNKNOWN
Conditions: PFS|OS|Quality of Life
Interventions: DRUG: NACT (Paclitaxel + Cisplatin or carboplatin)|PROCEDURE: radical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance and Antiretroviral Activity of Dasatinib: a Pilot Clinical Trial in Patients With Recent HIV-1 Infection
Status: RECRUITING
Conditions: Recent HIV-1 Infection
Interventions: DRUG: Dasatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: Salivation in Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: dihydroergotine mesylate sustained-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3-Way Crossover Study to Compare the PK (Pharmokinetics) and to Evaluate the Effect of Food on the Bioavailability
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SMP-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Communication by Brain - Computer Interface in Amyotrophic Lateral Sclerosis:Feasibility Study
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: communication system P300 Speller
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Imaging Characteristics of uEXPLORER and Conventional PET/CT in Patients With Lung Cancer, Lymphoma, and Melanoma
Status: ENROLLING_BY_INVITATION
Conditions: Lung Neoplasm|Lymphoma|Melanoma|Fluorodeoxyglucose|Positron-emission Tomography
Interventions: DEVICE: uEXPLORER/mCT|DEVICE: mCT/uEXPLORER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a New Method for Instilling Eye Drops
Status: COMPLETED
Conditions: Ophthalmic Solutions|Glaucoma
Interventions: DRUG: Timolol maleate 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study for the Evaluation of the Efficacy of Vaccination With Autologous Tumor Cells Plus Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) - in - Adjuvant, Followed by Systemic Low-dose-interleukin-2 (IL-2) Administration, in Patients With High Risk Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: autologous tumor cells plus GM-CSF-in Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1a/1b Study to Evaluate the Safety of EZN-4176, in Adult Patients With Castration-Resistant Prostate Cancer
Status: SUSPENDED
Conditions: Prostatic Neoplasm
Interventions: DRUG: EZN-4176
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: New Options for Treating Knee Osteoarthritis Pain
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Reiki|BEHAVIORAL: Sham Reiki|BEHAVIORAL: Mindfulness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer
Status: COMPLETED
Conditions: Hyperparathyroidism|Parathyroid Neoplasms
Interventions: DRUG: AMG 073
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Fear of Cancer Recurrence in Danish Colorectal Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Fear of Cancer Recurrence|Colorectal Cancer|Anxiety|Health Anxiety|Bodily Distress Syndrome
Interventions: BEHAVIORAL: TG-iConquerFear|BEHAVIORAL: aTAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)
Status: RECRUITING
Conditions: KSHV Inflammatory Cytokine Syndrome (KICS)|Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease
Interventions: DRUG: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement.
Status: RECRUITING
Conditions: Bicuspid Aortic Valve|Aortic Valve Stenosis|Aortic Aneurysm|Heart Diseases|Valvular Heart Disease|Valvular Aortic Stenosis|Ascending Aorta Aneurysm
Interventions: DIAGNOSTIC_TEST: Echocardiographic assessment.|DIAGNOSTIC_TEST: Computed-tomography assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Pancreatic Neoplasms
Interventions: DRUG: LMB-100|DRUG: Nab-Paclitaxel|DEVICE: Mesothelin Expression|DRUG: LMB-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Tissue Samples From Patients With Ewing Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: GENETIC: DNA analysis|GENETIC: comparative genomic hybridization|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphic microsatellite marker analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myocardial Perfusion Magnetic Resonance Imaging Using Regadenoson
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a Maintenance Protocol After Surgical Treatment of Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Glycine air powder|PROCEDURE: Rubber cup polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of ASP1941 and Mitiglinide on Their Plasma Concentration
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP1941|Pharmacokinetics of Mitiglinide
Interventions: DRUG: ASP1941|DRUG: Mitiglinide calcium hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Study of Biomarkers of Stress Resilience: Role of ELK1 and GPR56
Status: NOT_YET_RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Depressive Disorder, Major|Anxiety Disorder
Interventions: OTHER: Clinical, cognitive and biological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Assess the Safety and Effectiveness of Test Product in Healthy Adult Human Subjects With Dry and Sensitive Skin.
Status: NOT_YET_RECRUITING
Conditions: Dry Skin|Sensitive Skin
Interventions: OTHER: Dew Restore Barrier Repair Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Adductor Canal Block for Anterior Cruciate Ligament Surgery
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Adductor canal block|DRUG: Levobupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders
Status: COMPLETED
Conditions: Thrombocytosis|Myeloproliferative Neoplasms
Interventions: DRUG: Anagrelide CR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Acupuncture on the Liver Meridian in Women With Diminished Ovarian Reserve
Status: RECRUITING
Conditions: Ovarian Reserve|Acupuncture Therapy|Meridian
Interventions: OTHER: electropuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Marginal Adaptation, Shade Matching, of Polychromatic Feldspathic VS Polychromatic Hybrid Ceramic Laminate Veneer
Status: NOT_YET_RECRUITING
Conditions: Adaptation Reaction|Tooth Color|Patient Satisfaction
Interventions: OTHER: Multicolor hybrid ceramic laminate veneers.|OTHER: Multicolor fieldspathic ceramic laminate veneers.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Vaginal Dinoprostone Versus Misoprostone in Abdominal Myomectomy
Status: COMPLETED
Conditions: Myoma;Uterus
Interventions: DRUG: Dinoprostone|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Split-Blind Clinical Investigation to Compare the Performance and Safety of Inion GTR™ Biodegradable Membrane System to Resorbable Bilayer Bio-Gide®-Membrane of Geistlich Biomaterials in Enhancing Bone Regeneration After Removal of Wisdom Teeth.
Status: COMPLETED
Conditions: Bone Regeneration Following Wisdom Teeth Extraction
Interventions: DEVICE: guided bone regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor vs. Clopidogrel in Post PCI Patients
Status: COMPLETED
Conditions: Stable Chronic Angina
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer (TNBC) Patients
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Nivolumab|DRUG: Cisplatin|DRUG: Low dose doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine
Status: RECRUITING
Conditions: COVID-19|SARS CoV 2 Virus|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DEVICE: A&M Breathalyzer PROTECT Kiosk
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Efficacy and Safety of Abatacept Administered Subcutaneously (SC) in Children and Adolescents With Active Polyarticular Juvenile Idiopathic Arthritis (pJIA) and Inadequate Response (IR) to Biologic or Non Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs)
Status: COMPLETED
Conditions: Active Polyarticular Juvenile Idiopathic Arthritis
Interventions: BIOLOGICAL: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SHINE-CTO Trial
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Chronic Total Occlusion of Coronary Artery|Percutaneous Transluminal Coronary Angioplasty
Interventions: PROCEDURE: Chronic Total Occlusion Percutaneous Coronary Intervention|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy of the Skeletal Disease of Type 2 Diabetes With Denosumab
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Osteoporosis
Interventions: DRUG: Denosumab 60 mg/ml [Prolia]|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?
Status: RECRUITING
Conditions: Safety Issues|Efficacy
Interventions: OTHER: Mesenchymal Stem Cells|OTHER: Comparative placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of eCoin at Sensory and Subsensory Amplitudes
Status: ACTIVE_NOT_RECRUITING
Conditions: Urge Incontinence
Interventions: DEVICE: eCoin Peripheral Neurostimulator System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1
Status: RECRUITING
Conditions: Autosomal Dominant Hypocalcemia (ADH)
Interventions: DRUG: Encaleret|DIETARY_SUPPLEMENT: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of The Honeymoon Phase of Type 1 Diabetes: A Comparison of Insulins Detemir, Glargine and NPH
Status: TERMINATED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin detemir|DRUG: Glargine|DRUG: NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Diameter of Double-lumen Tube Measured by Different Methods
Status: COMPLETED
Conditions: Therapeutic Procedural Complication
Interventions: DEVICE: The cuff of endotracheal and endobronchial is collapsed|DEVICE: The cuff of endotracheal and endobronchial is inflated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Status: COMPLETED
Conditions: Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Interventions: DIETARY_SUPPLEMENT: Scelectium Tortuosum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Investigate the Relative Bioavailability and Food Effect of an Oral Capsid Inhibitor Tablet Formulation Compared With Other Oral Tablet Formulations in Male and Female Healthy Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: VH4004280 Formulation A|DRUG: VH4004280 Formulation B|DRUG: VH4004280 Formulation C|DRUG: VH4004280 Formulation D|DRUG: VH4004280 Formulation E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial for Patients With Gestational Trophoblastic Disease
Status: COMPLETED
Conditions: Trophoblastic Neoplasms|Uterine Neoplasms|Hydatidiform Mole|Choriocarcinoma
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transport of Artificial Sweeteners During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related|Diabetes|IUGR
Interventions: DIETARY_SUPPLEMENT: Acesulfame K, cyclamate, saccharine, aspartame
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety Study of Pentoxifylline for the Treatment of Anemia
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: Erythropoietin|DRUG: Erythropoietin|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment
Status: RECRUITING
Conditions: Drug Resistant Tuberculosis
Interventions: OTHER: Nurse-Led Treatment in Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-in-Human Single Ascending Dose of GLPG0492
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0492|DRUG: placebo|DRUG: GLPG0492|DRUG: GLPG0492
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
Status: RECRUITING
Conditions: Stem Cell Transplant Complications|Sleep Disturbance
Interventions: BEHAVIORAL: DREAMS Program Video and Care Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lung and Breast Cancer Prevention by an Integrated Intervention of Maternal Smoking Cessation and Breastfeeding
Status: COMPLETED
Conditions: Smoking, Cigarette|Breastfeeding
Interventions: BEHAVIORAL: Integrated intervention of smoking cessation and breastfeeding|BEHAVIORAL: Attention placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation
Status: COMPLETED
Conditions: Irritable Bowel Syndrome Characterized by Constipation
Interventions: DRUG: Linaclotide 290 micrograms|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Biology of Chronic Preconditioning: Genomic and Physiologic Mechanisms of Response
Status: UNKNOWN
Conditions: Ischemic Preconditioning
Interventions: PROCEDURE: Remote ischemic preconditioning (RIPC)|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neonatal Pain Management and Pain Monitoring Using New Methods
Status: RECRUITING
Conditions: Pain, Acute|Procedural Pain|Infant
Interventions: BEHAVIORAL: Skin-to-skin contact|BEHAVIORAL: Mother's heartbeats as sound and vibration|DRUG: 30% oral glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: 20 mL of bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Feeding Study in Premature Infants
Status: COMPLETED
Conditions: Premature Infants
Interventions: OTHER: Liquid human milk fortifier|OTHER: Powder human milk fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Isoflavone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care
Status: COMPLETED
Conditions: Lower Extremity Problem|Rehabilitation|Knee Injuries
Interventions: PROCEDURE: PROM_R knee rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT