pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Management of Early-onset Fetal Growth Restriction: Angiogenic Factors Versus Feto-placental Doppler
Status: NOT_YET_RECRUITING
Conditions: Fetal Growth Retardation|Preeclampsia|Placenta Diseases
Interventions: DIAGNOSTIC_TEST: soluble fms-like tyrosine kinase to placental growth factor ratio (sFlt-1/PlGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nasal LPS Challenge in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Nasal LPS spray|OTHER: Experimental: Nasal LPS spray 1µg|OTHER: Experimental: Nasal LPS spray 10 µg|OTHER: Experimental: Nasal LPS spray 30 µg|OTHER: Experimental: Nasal LPS spray 100 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Arteriovenous Fistulae: Drug-eluting Balloon Angioplasty
Status: TERMINATED
Conditions: Stenosis of Arteriovenous Dialysis Fistula
Interventions: DEVICE: Paclitaxel (Taxol) eluting angioplasty balloon|DEVICE: high-pressure angioplasty balloon|DEVICE: low-pressure balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Comparison of Telmisartan + Hydrochlorothiazide With Amlodipine + Hydrochlorothiazide in the Control of Blood Pressure in Older Patients With Predominantly Systolic Hypertension (ATHOS Study)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan 80 mg + hydrochlorothiazide 12.5 mg|DRUG: Amlodipine 10 mg + hydrochlorothiazide 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Biofeedback in Dysphagia Therapy Post Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Dysphagia, Oropharyngeal
Interventions: BEHAVIORAL: Dysphagia therapy using surface EMG as biofeedback|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ET 50 for Post Caesarean Section Spinal Hypotension
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: 2 ml bupivacaine|DRUG: 1.5 ml bupivicaine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sacral Nerve Stimulation to Treat Urgency Urinary Incontinence With Wireless Neuromodulation
Status: WITHDRAWN
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: StimGuard Sacral Nerve Stimulator System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cosmetic Study to Improve the Appearance of Skin Afflicted With Mild to Moderate Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: OTHER: AO+Mist|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sodium Lactate and Brain Relaxation (LSD)
Status: COMPLETED
Conditions: Sodium Lactate|Intracranial Hypertension|Brain Relaxation
Interventions: DRUG: Sodium Lactate|DRUG: Mannitol 20% Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Lucerastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of TT-00420 Tablets Combined With Toripalimab Injection in Advanced Urological Tumors
Status: NOT_YET_RECRUITING
Conditions: Clear Cell Renal Carcinoma|Urothelial Carcinoma|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: TT-00420 + Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Transcutaneous Oxymetry Use in Thoracic Outlet Syndrome
Status: UNKNOWN
Conditions: Thoracic Outlet Syndrome
Interventions: DIAGNOSTIC_TEST: Transcutaneous Oximetry|DIAGNOSTIC_TEST: Photopletysmography|OTHER: Questionnaires of Quality of Life (QoL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ondansetron and Blood Coagulation
Status: RECRUITING
Conditions: Blood Coagulation Disorder
Interventions: DRUG: 0 ul of ondansetron|DRUG: 0.2 ul of ondansetron|DRUG: 2 ul of ondansetron|DRUG: 20 ul of ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of BXCL701 in Patients With Pancreatic Cancer
Status: WITHDRAWN
Conditions: Cancer of Pancreas|Cancer of the Pancreas|Neoplasms, Pancreatic|Pancreas Cancer|Pancreatic Cancer
Interventions: DRUG: Talabostat Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excel V 532 nm KTP Laser for Treatment of Erythematotelangiectatic Rosacea & Papulopustular Rosacea
Status: COMPLETED
Conditions: Erythematotelangiectatic Rosacea|Papulopustular Rosacea
Interventions: DEVICE: 532nm KTP Laser vs 595nm Pulse Dye Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial)
Status: RECRUITING
Conditions: Non-Convulsive Status Epilepticus
Interventions: DRUG: Rapid sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustained Acoustic Medicine for Knee Osteoarthritis Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Sustained Acoustic Device with 2.5% Diclofenac Patch|DEVICE: Placebo Sustained Acoustic Device with 0% Diclofenac Patch|DRUG: 1% Diclofenac Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Executive Function Training in Childhood Obesity: Food Choice, Quality of Life and Brain Connectivity
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: Executive function training|OTHER: Psychoeducation|DEVICE: Placebo non-adaptive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
Interventions: DRUG: Placebo|DRUG: BYM338
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Status: RECRUITING
Conditions: Mitral Regurgitation|Mitral Insufficiency|Mitral Valve Insufficiency|Cardiovascular Diseases|Valve Disease, Heart|Heart Valve Diseases|Functional Mitral Regurgitation|Degenerative Mitral Valve Disease
Interventions: DEVICE: Tendyne Mitral Valve System|DEVICE: MitraClip System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fitostimoline® Hydrogel Versus Saline Gauze Dressing in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: Fitostimoline ® hydrogel group|DRUG: Saline gauze group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Carcinoma
Interventions: DRUG: Pentoxifylline|RADIATION: FOLFOX|RADIATION: XELOX|DRUG: Monoclonal antibodies (target therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Aflibercept (Eylea®) on Choroidal Neovascularization (Type 3)
Status: COMPLETED
Conditions: Type 3 Choroidal Neovascularization
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeuroCognition After Carotid Recanalization
Status: COMPLETED
Conditions: Cognition Disorder|Stroke|Occlusion Carotid
Interventions: PROCEDURE: Endovascular intervention|DRUG: Aspirin and Clopidogrel (maximal medical Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Proper Insulin Injection Technique in the Treatment of Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Lipohypertrophy
Interventions: BEHAVIORAL: Optimal insulin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BX-1 in Spasticity Due to Multiple Sclerosis
Status: COMPLETED
Conditions: Spasticity Due to Multiple Sclerosis
Interventions: DRUG: BX-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Safe Antibiotic Prescribing in Telehealth
Status: COMPLETED
Conditions: Acute Respiratory Infection|Telehealth
Interventions: BEHAVIORAL: Trending Feedback|BEHAVIORAL: Benchmark Peer Comparison Feedback|BEHAVIORAL: Private Commitment|BEHAVIORAL: Public Commitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open-Label, Phase I/II Study of Nilotinib (Tasigna) and MEK-162 (ARRY-162) Used in Combination for Patients With Refractory or Advanced Chronic Myeloid Leukemia and Philadelphia Positive Acute Leukemia (Protocol CAMN107AUS41T)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: MEK-162|DRUG: Nilotinib|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Swallowing and Oral Care Program in Patients Following Prolonged Endotracheal Intubation
Status: COMPLETED
Conditions: Dysphagia|Endotracheal Intubation|Intake Status|Swallowing Status
Interventions: PROCEDURE: Swallowing and Oral Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Thinking Skills for Work (TSW)Home Practice Program With Traditional TSW Program
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depression
Interventions: BEHAVIORAL: TSW-HP|BEHAVIORAL: TSW-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Mindfulness Apps to Decrease Anxiety in People With Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: AmDTx-PCSP|OTHER: AmDTx-2048|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Brensocatib|DRUG: Rifampin|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Spanish or English Language Versions of Mindfulness Meditation on Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Mindful Awareness Practices- English|BEHAVIORAL: Mindful Awareness Practices- Spanish|BEHAVIORAL: Health Education - English|BEHAVIORAL: Health Education - Spanish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Misoprostol Versus Intravenous Oxytocin Infusion During Cesarean Delivery
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanism of tDCS-induced Learning Enhancement - the Role of Serotonin
Status: COMPLETED
Conditions: Healthy Young and Older Adults
Interventions: PROCEDURE: tDCS|DRUG: Citalopram|OTHER: sham-tDCS + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide
Status: TERMINATED
Conditions: Epilepsy, Partial
Interventions: DRUG: Lacosamide|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers
Status: COMPLETED
Conditions: Reflux Oesophagitis
Interventions: DRUG: YF476
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: In Vivo Versus Augmented Reality Exposure for Small Animal Phobia
Status: COMPLETED
Conditions: Phobic Disorders
Interventions: BEHAVIORAL: In Vivo Exposure for Animal Phobia following Öst´s guidelines|BEHAVIORAL: Augmented Reality Exposure for Animal Phobia following Öst´s guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the C8 Nerve Root Block During Interscalene Block for Anesthesia of the Posterior Aspect of the Shoulder
Status: COMPLETED
Conditions: Brachial Plexus Block|Shoulder Pain
Interventions: PROCEDURE: Conventional interscalene block|PROCEDURE: Interscalene block with C8 root block|DRUG: 0.75% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALFA-0703 Study in Older Patients With Acute Myeloblastic Leukemia (AML)
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Vesanoid (ATRA)|DRUG: AZACITIDINE (VIDAZA)|DRUG: CYTARABINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HuMax-CD20, a New Drug to Treat Early Stage Non-Hodgkin´s Follicular Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma, Follicular
Interventions: DRUG: HuMax-CD20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early-feasibility Study to Evaluate Usability and Safety of the Watch-Transcutaneous Electrical Acustimulation (TEA) Device
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Watch-TEA group|DEVICE: Tethered TEA device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: National Mobile Asthma Management System-E Project
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Mobile Asthma Management System|BEHAVIORAL: traditional Asthma Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RECHARGE: A Brief Psychological Intervention to Build Resilience in Healthcare Workers During COVID-19
Status: UNKNOWN
Conditions: Stress|Burnout|Anxiety|Depression|Covid19
Interventions: BEHAVIORAL: RECHARGE|BEHAVIORAL: Self Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH12852 After Oral Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH12852|DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Gaming Intervention for Older People in Long-term Care
Status: COMPLETED
Conditions: Depressive Symptoms|Aging|Loneliness|Sedentary Behavior|Social Isolation|Physical Inactivity
Interventions: DEVICE: Yetitablet gaming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Deep Molecular Response in Adult Patients With CML in Chronic Phase Treated With Nilotinib Firstline.
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Embryonic Stem Cell-Derived Cardiomyocyte Therapy for Chronic Ischemic Left Ventricular Dysfunction
Status: RECRUITING
Conditions: Chronic Ischemic Left Ventricular Dysfunction
Interventions: DRUG: Human Embryonic Stem Cell-Derived Cardiomyocyte 50M cells|DRUG: Human Embryonic Stem Cell-Derived Cardiomyocyte 150 cells|DRUG: Human Embryonic Stem Cell-Derived Cardiomyocyte 300M cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Processed Amniotic Fluid (pAF) for the Treatment of Chronic Wounds
Status: TERMINATED
Conditions: Wounds and Injuries
Interventions: DRUG: Processed Amniotic Fluid|OTHER: Standard of Care Wound Treatment Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Low Dose Psilocybin|DRUG: Placebo|DRUG: Medium Dose Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Topical Ketamine Versus Caudal Ketamine for Postoperative Analgesia in Children Undergoing Inguinal Herniotomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketamine|DRUG: Ketamine|DRUG: Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Rapid Antioxidant Protection and Immune Modulating Effects.
Status: UNKNOWN
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Ergothioneine, 25 miligrams|DIETARY_SUPPLEMENT: Ergothioneine, 25 miligrams, daily for 1 week
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Estrogen Blockade of the Breast With Exemestane and Raloxifene in Postmenopausal Women With a History of Breast Cancer Who Have No Clinical Evidence of Disease
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Raloxifene followed by combination therapy|DRUG: Exemestane followed by combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maxillofacial Rehabilitation Using Motor Imagery vs Sham After Orthognathic Surgery
Status: NOT_YET_RECRUITING
Conditions: Maxillofacial Abnormalities
Interventions: BEHAVIORAL: Motor imagery of the jaw|BEHAVIORAL: Control task (Sudoku or Crossword puzzle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of an Otic Formulation in Acute Otitis Media With Tympanostomy Tubes
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: Moxidex otic solution|DRUG: Ofloxacin otic solution|DEVICE: Tympanostomy tubes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Histone Deacetylase Inhibitors (HDAC)
Status: TERMINATED
Conditions: Histone Deacetylase (HDAC) Activity
Interventions: DIETARY_SUPPLEMENT: BSE placebo|DIETARY_SUPPLEMENT: Garlic oil|DRUG: BSE|DIETARY_SUPPLEMENT: Garlic Oil Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Cold pressor task (CPT)|DIAGNOSTIC_TEST: index NOL|BEHAVIORAL: Playback Experiments|DIAGNOSTIC_TEST: Video-pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Antimicrobial Prophylaxis Versus Placebo for Infection Prevention in HCC After Liver Resection
Status: SUSPENDED
Conditions: Hepatocellular Carcinoma|Postoperative Infection
Interventions: DRUG: postoperative antimicrobial prophylaxis|OTHER: No postoperative antimicrobial prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Drainage Seton With Flap Versus EAS Preserving Seton in Treatment of Transsphincteric Anal Fistula
Status: COMPLETED
Conditions: Anal Cancer
Interventions: PROCEDURE: Drainage seton with flap|PROCEDURE: EAS sparing seton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Computational Drug Repurposing for All EBS Cases
Status: RECRUITING
Conditions: Epidermolysis Bullosa|Healthy|Genetic Skin Disease|Epidermolysis Bullosa Simplex|Epidermolysis Bullosa, Junctional|Epidermolysis Bullosa Dystrophica
Interventions: PROCEDURE: Experimental Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Pregabalin as Preemptive Analgesia in Abdominal Hysterectomy
Status: TERMINATED
Conditions: Pain, Postoperative|Analgesia|Gabapentin Adverse Reaction|Opioid Abuse
Interventions: DRUG: Pregabalin 300mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Proprioceptive Isokinetic Repositioning, Functional Testing, and a Self-reported Questionnaire Before and After Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: ACL Tear|ACL - Anterior Cruciate Ligament Deficiency
Interventions: DEVICE: Proprioception measurement on isokinetic dynamometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Do Patients With Fish or Shellfish Allergy Tolerate the Consumption of Fish Oil Supplements? A Clinical Study
Status: COMPLETED
Conditions: Food Hypersensitivity
Interventions: DIETARY_SUPPLEMENT: Fish oil|DIETARY_SUPPLEMENT: Cod oil|DIETARY_SUPPLEMENT: Krill oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Study of Transarterial Chemoembolization and Percutaneous Ethanol Injection for Multiple, Small HCCs
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Transarterial chemoembolization|PROCEDURE: Percutaneous ethanol injection therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Effectiveness of Fostamatinib Compared to Placebo in Patients in Asia With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Fostamatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport
Status: RECRUITING
Conditions: Ligament Knee Injury|Anterior Cruciate Ligament Rupture
Interventions: OTHER: Usual rehabilitation|OTHER: Rehabilitation optimized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy, Bevacizumab, Paclitaxel, and Carboplatin in Treating Patients With Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer at High Risk for Hemoptysis Caused by Bevacizumab
Status: COMPLETED
Conditions: Adenosquamous Cell Lung Cancer|Drug/Agent Toxicity by Tissue/Organ|Hemoptysis|Squamous Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: paclitaxel|DRUG: carboplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
Status: TERMINATED
Conditions: Medulloblastoma
Interventions: DRUG: Lomustine|DRUG: Vincristine|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Follow-up in Primary Health Care for Diabetes-related Foot Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot|Foot Ulcer
Interventions: PROCEDURE: Telemedicine follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Summer Harvest Adventure: A Garden-based Obesity Prevention Program for Children Residing in Low-resource Communities
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Summer Harvest Adventure|BEHAVIORAL: My Summer Plate (MSP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The NORDSTEN Study - Degenerative Spondylolisthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Degenerative Spondylolisthesis
Interventions: PROCEDURE: Decompression alone|PROCEDURE: Decompression followed by fusion with instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE]
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: tiotropium/olodaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Immune Response to Licensed Influenza Vaccines in Children and Adolescents
Status: COMPLETED
Conditions: Immune Response to Influenza Vaccine|Influenza A Virus Infection|Influenza B Virus Infection
Interventions: BIOLOGICAL: LAIV|BIOLOGICAL: IIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess Safety, Tolerability, Pharmacokinetics and Clinical Activity of AMP-110 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: AMP-110|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Gonadotrophin Releasing Hormone Analogues on Oocyte and Embryo Quality
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Gonadotropin-Releasing Hormone Analogue|DRUG: Gonadotropin releasing hormone antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exalt D Single-use Duodenoscope in ERCP Procedures in China
Status: WITHDRAWN
Conditions: Cholangiopancreatography
Interventions: DEVICE: ExaltTM Model D Single-Use Duodenoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of the LEISH-F2 + MPL-SE Vaccine With SSG for Patients With PKDL
Status: COMPLETED
Conditions: Post Kala Azar Dermal Leishmaniasis
Interventions: BIOLOGICAL: LEISH-F2 + MPL-SE vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoradiotherapy Sequenced Radical Surgery for Colorectal Cancer With PALNM
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms Malignant|Lymph Node Excision|Chemoradiotherapy
Interventions: PROCEDURE: Radical surgery with PALND|PROCEDURE: Radical surgery without PALND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sodium Fusidate Ointment Compared to Petrolatum for Wound Healing Following Cauterization
Status: COMPLETED
Conditions: Seborrheic Keratosis|Acrochordon
Interventions: DRUG: Sodium Fusidate 2 % Topical Ointment|DRUG: Petrolatum ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: sulfadoxine-pyrimethamine plus amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial
Status: ENROLLING_BY_INVITATION
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: The Laterally Closed Tunnel Technique with SCTG|DRUG: The Laterally Closed Tunnel Technique with collagen matrix mucograft|PROCEDURE: Modified Coronally Advanced Tunnel Technique with SCTG.|DRUG: Modified Coronally Advanced Tunnel Technique with collagen matrix mucograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Anti-Glaucoma Medications on the Ocular Surface
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: Travoprost|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for The Treatment of Knee Osteoarthritis (KOA).
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: UMC119-06-05|DEVICE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Archimedes ™ System for Transparenchymatous Access to Pulmonary Nodules.
Status: TERMINATED
Conditions: Bronchoscopy|Lung Cancer|Solitary Pulmonary Nodule
Interventions: DEVICE: Archimedes procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase Ib Study of the Safety, Tolerability and Efficacy of LY2780301 in Combination With Gemcitabine
Status: COMPLETED
Conditions: Solid Tumors and Non-Hodgkin's Lymphoma
Interventions: DRUG: LY2780301|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry
Status: TERMINATED
Conditions: Pulp Necroses|Tooth, Nonvital
Interventions: BIOLOGICAL: Single-visit regeneration protocol|BIOLOGICAL: Multiple-visits regeneration protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of New Formulation and Approved Formulation for Levothyroxine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Reference Eutirox®|DRUG: Test Eutirox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Severe Sepsis in Children - IMPRESS-C
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Chronic Kidney Disease|Hypertension
Interventions: DRUG: Iodohippurate|PROCEDURE: 24 hour ambulatory Blood Pressure|PROCEDURE: Peripheral Arterial Tonometry|PROCEDURE: Pulse Wave Velocity|DRUG: Gadolinium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MGPOCUS Assisted Bronchoscopy in Difficult Endotracheal Intubation
Status: NOT_YET_RECRUITING
Conditions: Airway Management
Interventions: PROCEDURE: MGPOCUS-assisted bronchoscope-guided intubation|PROCEDURE: Bronchoscope-guided intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OT-101 in Combination With Atezolizumab for the Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|PROCEDURE: Magnetic Resonance Imaging|DRUG: Trabedersen (OT-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality-based Induction to Improve Positive Body Image in Low Back Pain Patients.
Status: COMPLETED
Conditions: Chronic Low-back Pain|Low Back Pain
Interventions: BEHAVIORAL: Positive Appreciation of Body Functionality Induction|BEHAVIORAL: Negative Appreciation of Body Functionality Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TBTC Study 24: Intermittent Treatment of TB With Isoniazid Resistance or Intolerance
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Rifampin|DRUG: Pyrazinamide|DRUG: Ethambutol|DRUG: REZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucosamine Unum In Die [Once A Day] Efficacy (GUIDE) Trial: Glucosamine Sulfate in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Glucosamine sulfate|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Exenatide Treatment on Mean 24-Hour Heart Rate in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)
Status: COMPLETED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Gemcitabine Hydrochloride|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Pemetrexed Disodium|BIOLOGICAL: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Menopause Osteoporosis and Bone Intervention Using Lifestyle Exercise.
Status: TERMINATED
Conditions: Osteoporosis, Postmenopausal
Interventions: OTHER: Jumping exercise|OTHER: Balance exercise (sham control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinoids in ANCA Small Vessel Vasculitis: Silencing Autoantigens
Status: WITHDRAWN
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: DRUG: Retinoic acid|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on Botulinum Toxin B as Treatment for Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Botulinum B Toxin|OTHER: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health
Status: NOT_YET_RECRUITING
Conditions: Postpartum Depression|Insomnia|Stress
Interventions: BEHAVIORAL: Improving sleep health and resilience during pregnancy|BEHAVIORAL: Information on pregnancy-related issues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Pracinostat|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Controlled Feedback on the Rehabilitation of Individuals With Disability Due to Stiff Shoulder Following Trauma
Status: UNKNOWN
Conditions: Fracture Humerus
Interventions: OTHER: Biofeedback via motion capture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Case Management Study Targeted to Reduce Health Care Utilization for Frequent Emergency Department Visitors
Status: UNKNOWN
Conditions: The Focus is to Investigate Effect of a Case Management Interventions in Frequent Visitors to Emergency Departments
Interventions: BEHAVIORAL: Case-management intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nitrate and Exercise-induced Cardiac Troponin T in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Dietary nitrate beverage|DIETARY_SUPPLEMENT: NaCl beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exit Strategy After Percutaneous Nephrolithotomy: Large or Small Bore Tube?
Status: UNKNOWN
Conditions: Urolithiasis|Nephrolithotomy|Percutaneous Nephrolithotomy (PNL)|Nephrostomy Tube (NT)|Pain
Interventions: PROCEDURE: large-bore nephrostomy tube (LBNT)|PROCEDURE: small-bore nephrostomy tube (SBNT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC (DFMO)
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Difluoromethylornithine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer
Status: COMPLETED
Conditions: Neoplasms|Breast Neoplasms
Interventions: DRUG: Xentuzumab|DRUG: Abemaciclib|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Fulvestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.
Status: COMPLETED
Conditions: White Spot Lesion|Orthodontic Appliance Complication
Interventions: OTHER: CPP-ACP paste|OTHER: CPP-ACPF paste|OTHER: 1.25% fluoride gel|OTHER: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of XL019 in Adults With Myelofibrosis
Status: TERMINATED
Conditions: Myeloproliferative Disorders|Myelofibrosis|Polycythemia Vera|Thrombocythemia, Essential
Interventions: DRUG: XL019
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management
Status: RECRUITING
Conditions: Thoracoscopic Lobectomy
Interventions: DRUG: HR18034|DRUG: Ropivacaine Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurological Outcome With Carotid Artery Stenting
Status: COMPLETED
Conditions: Carotid Artery Disease|Carotid Artery Stenosis|Stroke|Transient Ischemic Attack
Interventions: PROCEDURE: Angioplasty|DEVICE: Stent|OTHER: Neurological and neuropsychological evaluations|PROCEDURE: Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Self-administered Misoprostol to Prevent Bleeding After Childbirth in the Community (MamaMiso)
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BEHAVIORAL: Family-based Behavioral Weight Loss Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Concussion and Melatonin
Status: RECRUITING
Conditions: Concussion, Mild|Concussion, Brain|Pediatric ALL
Interventions: DRUG: Melatonin 3 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on BReast Cancer Patient Care Using chAtbot and Video Education for Radiation Therapy (BRAVE)
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: OTHER: Video + Chatbot|OTHER: Video + Paper|OTHER: Paper + Chatbot|OTHER: Paper + Paper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER