pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety of MRI Compatible Hardware for MRI-based Image Guidance During Spine Surgery
Status: TERMINATED
Conditions: Thoracic Spine Neoplasm
Interventions: DEVICE: Magnetic Resonance Imaging|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prosocial Behavior Can Safeguard Mental Health and Foster Emotional Well-being During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Happiness|Anxiety|Depression|Morality
Interventions: BEHAVIORAL: Self-focused acts|BEHAVIORAL: Prosocial acts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Status: COMPLETED
Conditions: Hemodynamic Response|Acute Appendicitis|Complication of Treatment|Opioid Consumption|Pneumoperitoneum
Interventions: DRUG: Intravenous lidocaine|DRUG: Normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH)
Status: RECRUITING
Conditions: Isolated Hypogonadotropic Hypogonadism|Kallmann Syndrome|Infertility
Interventions: DRUG: Human Chorionic Gonadotropin|DRUG: human menopausal gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Optimal Nutrient Mix to Acutely Increase Plasma Ketones
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: 25g MCT-based nutrient mix|DIETARY_SUPPLEMENT: 25g MCT-based nutrient mix + cofactors|DIETARY_SUPPLEMENT: non-ketogenic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Body Weight and Composition on Iron Absorption and Blood Volume
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: labeled iron solution|DIETARY_SUPPLEMENT: labeled iron solution and ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of IBI311 in Subjects With Inactive or Active Thyroid Eye Disease
Status: NOT_YET_RECRUITING
Conditions: Thyroid Eye Disease
Interventions: BIOLOGICAL: IBI311 (20 mg)|BIOLOGICAL: IBI311 (3-20 mg)|BIOLOGICAL: IBI311 (10 mg)|BIOLOGICAL: IBI311 (3-10mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: DRUG: vorinostat|PROCEDURE: therapeutic conventional surgery|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: E/C/F/TAF|DRUG: E/C/F/TDF|DRUG: E/C/F/TDF Placebo|DRUG: E/C/F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Vignette-based Randomized Controlled Trial to Evaluate the Impact of Supervisor's Role on Research Practices of Doctoral Students
Status: UNKNOWN
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: Vignette with emphasis on supervisor's opinion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aumolertinib With or Without Chemotherapy as 1st Line Treatment in Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Sensitizing EGFR Mutations
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Aumolertinib|DRUG: Placebo Aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension
Status: TERMINATED
Conditions: Anorexia|Cachexia|Weight Loss
Interventions: DRUG: Megestrol acetate concentrated suspension 110 mg/mL|DRUG: Megestrol acetate concentrated suspension 60 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on the Scalp Lipids and TEWL of a 1% Selenium Disulfide and 1% Salicylic Acid Antidandruff Shampoo on Dandruff Scalp
Status: UNKNOWN
Conditions: Dandruff
Interventions: OTHER: 1% Selenium Disulfide (SeS2)/1% salicylic acid-based shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: MMV688533
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lyophilized Fecal Transplant vs Lyophilized Fecal Filtrate in Recurrent C Diff Infection
Status: COMPLETED
Conditions: Enterocolitis|Recurrent Clostridium Difficile Infection
Interventions: BIOLOGICAL: LFMT|BIOLOGICAL: LSFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of SML in Patients With Dry Age-related Macular Degeneration and Myopic Maculopathy
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration|Lens, Intraocular|Myopic Maculopathy
Interventions: DEVICE: Scharioth Macula Lens (SML, Medicontur)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an eHealth System to Reduce Depression and Increase Resilience After SCI
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: eHealth Intervention|OTHER: Active Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Life After STroke - the LAST Study
Status: COMPLETED
Conditions: Cerebral Infarction|Cerebral Hemorrhage
Interventions: BEHAVIORAL: Long term follow up by a coordinating physiotherapist|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Novel Electrolyzed Water Spray Treatment Discomfort, Redness and Swelling of the Skin Surrounding the Wound
Status: COMPLETED
Conditions: Skin Injury
Interventions: DEVICE: The novel electrolyzed water spray|DEVICE: The saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Frailty in 12 Subjects
Status: TERMINATED
Conditions: Aging|Inflammation|Frailty
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: approved GnRH agonist|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide and Duvalisibon for the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma|Relapsed Peripheral T-Cell Lymphoma|Refractory T-Cell Lymphoma
Interventions: DRUG: Chidamide combined with Duvillisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of HP802-247 in Dystrophic Epidermolysis Bullosa
Status: WITHDRAWN
Conditions: Dystrophic Epidermolysis Bullosa
Interventions: BIOLOGICAL: HP802-247|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anisotropic Textile Braces for Adolescent Idiopathic Scoliosis
Status: ENROLLING_BY_INVITATION
Conditions: Scoliosis
Interventions: DEVICE: Anisotropic Textile Braces
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Minocycline (Solodyn) and Oral Minocycline (Solodyn) Plus Azelaic Acid (Finacea) for Acne Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Minocycline 45 MG|DRUG: Azelaic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: G-CSF Plus NAC In Severe Alcoholic Hepatitis
Status: UNKNOWN
Conditions: Alcoholic Hepatitis
Interventions: DRUG: standard medical therapy|DRUG: G-CSF|DRUG: n-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mFOLFIRINOX as First-Line Chemotherapy in Treating Chinese Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: Neuromuscular Electrical Stimulation Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Sitagliptin Phosphate/metformin Hydrochloride Tablets(JANUMET®,50mg/850mg)|DRUG: Sitagliptin Phosphate/metformin Hydrochloride Tablets (50mg/850mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGB for COVID-induced Parosmia
Status: COMPLETED
Conditions: COVID-19-Induced Parosmia
Interventions: DRUG: Stellate Ganglion Block|DRUG: Placebo Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for Patients With Non-Small Cell Lung Cancer Who Are Non-Smokers
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National Emphysema Treatment Trial (NETT)
Status: COMPLETED
Conditions: Emphysema|Lung Diseases|Lung Diseases, Obstructive|Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Lung volume reduction surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: ACT-541478 10 mg|DRUG: ACT-541478 30 mg|DRUG: ACT-541478 100 mg|DRUG: ACT-541478 300 mg|DRUG: ACT-541478 1000 mg|DRUG: ACT-541478 high or low dose (or placebo)|DRUG: ACT-541478 dose E1|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Ibrexafungerp (SCY-078) vs Standard-of-Care Following IV Echinocandin in the Treatment of Invasive Candidiasis
Status: COMPLETED
Conditions: Mycoses|Candidiasis, Invasive|Candidemia
Interventions: DRUG: SCY-078|DRUG: Fluconazole|DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family, Responsibility, Education, Support, and Health for Latino Caregivers (FRESH-LC)
Status: RECRUITING
Conditions: Childhood Obesity|Minority Health
Interventions: BEHAVIORAL: Parent-based treatment- All caregivers (PBT-AC)|BEHAVIORAL: Health Education (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Alpha1-Proteinase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Polyethylene Glycolic Acid or Tachocomb to Prevent Pancreatic Fistula Following Distal Pancreatectomy
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: DEVICE: Tachocomb|DEVICE: Polyglycolic acid (PGA) (Neoveil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Omega 3 for Treatment of Depression in Patients With Heart Failure
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: 2:1 EPA/DHA|DRUG: High EPA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Latisse (Bimatoprost .03% Opthalmic Solution) for the Treatment of Hypotrichosis of the Eyebrows: Latisse Versus Placebo
Status: COMPLETED
Conditions: Hypotrichosis
Interventions: DRUG: topical bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Endoscopic Mastectomy in Patients With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Nipple-Sparing Mastectomy, with immediate breast reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia.
Status: COMPLETED
Conditions: Pregnancy|Labor Pain
Interventions: PROCEDURE: CSE with 10 ml EVE|PROCEDURE: CSE without EVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiepileptic Drugs and Vascular Risk Markers
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: phenytoin|DRUG: valproate|DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
Status: TERMINATED
Conditions: Lower Leg Wound
Interventions: DEVICE: WoundWand™ Debridement Device|DEVICE: Standard of Care sharp debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy
Status: COMPLETED
Conditions: Degenerative Spinal Stenosis|Disk Herniation
Interventions: DEVICE: Hyalospine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: PDC-1421 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
Status: NOT_YET_RECRUITING
Conditions: Postoperative Nausea and Vomiting|Sore-throat|Dental Caries
Interventions: PROCEDURE: throat pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Safety and Efficacy of Pazopanib and Gemcitabine in Persistent or Relapsed Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Gemcitabine|DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid on Tissue Healing After Removal of Impacted Mandibular Third Molars (LM3)
Status: UNKNOWN
Conditions: Tooth, Impacted
Interventions: DEVICE: Hyaluronic acid gel|DEVICE: Hyaluronic acid gel + carrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome® for Treatment of Invasive Aspergillosis (IA).
Status: COMPLETED
Conditions: Aspergillosis
Interventions: DRUG: Anidulafungin, VER002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test Efficacy of Biodegradable and Permanent Limus-Eluting Stents
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: Nobori® (Biodegradable polymer limus-eluting stents)|DEVICE: Xience-V® (Permanent polymer limus-eluting stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Natural Killer Cell Therapy for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Autologous Natural Killer Cell Therapy|DEVICE: Clinimacs Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion Chemotherapy With Fruquintinib for Colorectal Cancer Liver Metastases As Third-line Therapy
Status: RECRUITING
Conditions: Advanced Colorectal Carcinoma|Liver Metastasis Colon Cancer
Interventions: DRUG: Fruquintinib|PROCEDURE: Hepatic Arterial Infusion Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Single Arm Study of Intraoperative Radiotherapy for Locally Advanced or Recurrent Rectal Cancer
Status: COMPLETED
Conditions: Malignant Rectal Neoplasm|Recurrent Tumor
Interventions: RADIATION: intraoperative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Patients Followed for a Multiple Sclerosis and Treated by Dimethyl-fumarate
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant Administration of the Novavax Vaccine and a 20-valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years
Status: NOT_YET_RECRUITING
Conditions: COVID-19|Pneumococcal Infections
Interventions: BIOLOGICAL: NVX|BIOLOGICAL: PCV20|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Post Operative Pain
Interventions: DRUG: ketorolac and light marcaine|DRUG: light marcaine|DRUG: Corticosteroids injection|DRUG: Diclofenac Sodium Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Irreversible Electroportion in Unresectable Liver Cancer Close to Diaphragmatic Dome
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DEVICE: Irreversible electroporation (IRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Teriparatide to Accelerate Fracture Healing
Status: TERMINATED
Conditions: Pelvic Fracture
Interventions: DRUG: Teriparatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blue Light Photobiomodulation Therapy on Neuroischemic Patients
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: debridement|DEVICE: Offloading|DEVICE: Advanced dressing|DEVICE: Blue Light Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Skeletal Muscle Paralysis on Metabolism in Hypothermic Patients After Cardiac Arrest
Status: COMPLETED
Conditions: Critical Illness|Cardiac Arrest
Interventions: DRUG: Rocuronium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fimasartan/Amlodipine Combination Phase III
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan and Amlodipine|DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Early ADL Education on Outcomes Post DRF ORIF
Status: RECRUITING
Conditions: Distal Radius Fractures
Interventions: BEHAVIORAL: ADL/Postoperative Instruction|BEHAVIORAL: Postoperative Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes
Interventions: OTHER: Glucagon|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraoperative Goal-directed Blood Pressure and Dexmedetomidine on Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Blood Pressure|Dexmedetomidine|High-risk Patients|Abdominal Surgery|Postoperative Complications
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo|OTHER: Goal-directed blood pressure management|OTHER: Routine blood pressure management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Placebo|DRUG: rhNRG-1 Dose 1|DRUG: rhNRG-1 Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-582949 in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BMS-582949|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emoji-based Attention Bias Modification Training for Depressive Young Adults
Status: UNKNOWN
Conditions: Depressive Symptoms|Mood Disorders
Interventions: BEHAVIORAL: Attention Bias Modification|BEHAVIORAL: Deep-breathing training|BEHAVIORAL: Sham Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prostate Bipolar Enucleation and Resection Versus Open Prostatectomy
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: transurethral bipolar enucleation and resection of the prostate|PROCEDURE: open surgical transvesical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Resection Versus Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma Complicated by Portal Vein Tumor Thrombosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma With PVTT
Interventions: PROCEDURE: hepatic resection|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Vabicaserin in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: vabicaserin|DRUG: risperidone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining MRI and CEUS to Diagnose Small Cervical Lymph Node Metastases in NPC Patients
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DIAGNOSTIC_TEST: MRI Scanning|DIAGNOSTIC_TEST: Contrast-Enhanced Ultrasonography|DIAGNOSTIC_TEST: Ultrasound-guided Lymph Node Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Looking at End Expiratory Pressure for Altitude Illness Decrease (SLEEP-AID)
Status: COMPLETED
Conditions: Acute Mountain Sickness
Interventions: DEVICE: Theravent|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spasticity, Muscle|Extracorporeal Shock Wave Therapy
Interventions: OTHER: Radial extracorporeal shock wave therapy (rESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Ultrasound-guided Remote Ischemic Conditioning on Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Ultrasound-guided remote ischemic conditioning|OTHER: Traditional remote ischemic conditioning|PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study Using Zone-MPC Controller (Zone-Model Predictive Control) and Health Monitoring System (HMS)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Sansum Closed-Loop Artificial Pancreas|DEVICE: Insulin infusion pump|DEVICE: Continuous Glucose Monitor|DEVICE: zone-Model Predictive Control algorithm|DEVICE: Safety Health Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Intermittent Normoxia Reduces Myocardial Reperfusion Injury
Status: UNKNOWN
Conditions: Hyperoxia
Interventions: PROCEDURE: intermittent normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT), Patient Reported Outcomes and Safety in Men With Premature Ejaculation (PE)
Status: COMPLETED
Conditions: Premature Ejaculation
Interventions: DRUG: IX-01 400 mg|DRUG: Placebo|DRUG: IX-01 800 mg|DRUG: IX-01 1200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IPI-145 Single Ascending, Multiple Ascending, Food Effect and Drug-Drug-Interaction Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: IPI-145|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety and Antipsoriatic Efficacy of BOS-475 in a Psoriasis Plaque Test
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: BOS-475|DRUG: Active ingredient-free vehicle cream|DRUG: Daivonex cream (calcipotriol 0.005%)|DRUG: Betnesol-V cream (betamethasone 0.1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Melphalan-Prednisone (MP) to MP Plus Thalidomide in the Treatment of Newly Diagnosed Very Elderly Patients (> 75 Years) With Multiple Myeloma
Status: TERMINATED
Conditions: Newly Diagnosed, Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: melphalan, prednisone|DRUG: melphalan, prednisone, thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improved Case Detection and Vector Control for Visceral Leishmaniasis
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: DEVICE: Inesfly Paint|DEVICE: IDWL (1m)|DEVICE: ITN (KO-Tab 123)|DEVICE: IRS (Delthamethrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia
Status: COMPLETED
Conditions: Malaria in Pregnancy
Interventions: DRUG: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Longterm Follow-up of Cardiac Patients With an Smartphone-Application
Status: COMPLETED
Conditions: Cardiac Rehabilitation|Mobile Health|Smartphone-application|Cardiac Disease|mHealth
Interventions: DEVICE: Smartphone-Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: CNM-Au8|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PPI-Rebound-Trial. A Study of the Clinical Relevance of the Acid Rebound Phenomena
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Effects of Prone Position in CARDS
Status: COMPLETED
Conditions: ARDS Due to Disease Caused by SARS Co-V-2|Right Ventricular Dysfunction
Interventions: PROCEDURE: before prone position|PROCEDURE: the first hour of prone position|PROCEDURE: the first hour of returning to the supine position
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Depatuxizumab mafodotin|DRUG: Temozolomide|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropsychological Profile of a Patient's Group With Multiple Sclerosis and Effect of a Cognitive Rehabilitation Program
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: OTHER: Cognitive training|OTHER: Placebo task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Effect of ENI Patented Whole Grape Extract on Antioxidant Status
Status: COMPLETED
Conditions: High Oxidation Stress|Oxidized LDL Level
Interventions: DIETARY_SUPPLEMENT: ENI Patented Whole Grape Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study Evaluating ET-01 in Subjects With Transfusion Dependent β-Thalassaemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Transfusion Dependent Beta-Thalassaemia
Interventions: BIOLOGICAL: ET-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Endotracheal Tube Fluctuation With Epigastric Compression Be Used as a Confirmation Method for Endotracheal Intubation?
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: DEVICE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy & Safety of RPh201 Treatment in Patients With Previous Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Status: TERMINATED
Conditions: Nonarteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: RPh201 Cohort A|OTHER: Placebo Cohort A|DRUG: RPh201 Cohort B|OTHER: Placebo Cohort B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Vernakalant Therapy to Amiodarone Therapy in Acute Management of Recent Onset Atrial Fibrillation (AF) (MK-6621-055)
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Vernakalant|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of the RIGHTEST™ Continuous Glucose Monitoring System for Blood Glucose Management in Persons With Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Device implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase IV Study of Cipro XR in Uncomplicated UTI
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: BEHAVIORAL: Cipro XR (Ciprofloxacin, BAYQ3939)|BEHAVIORAL: Cipro XR (Ciprofloxacin, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Oxaliplatin and Fluorouracil in Treating Patients With Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Computed Tomography-derived Fractional Flow Reserve STAT Trial
Status: TERMINATED
Conditions: Heart Disease, Coronary|Chest Pain|Acute Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: CTFFR-Guided Group Management|DIAGNOSTIC_TEST: SOC Group Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Ixekizumab|DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: H5N1 Vaccine Intramuscular Versus Intradermal in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated Influenza A Vaccine A/H5N1|BIOLOGICAL: Inactivated Influenza A Vaccine A/H5N1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Individually Adapted Immunosuppression in de Novo Renal Transplantation Based on Immune Function Monitoring: a Prospective Randomised Study
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: individual adapted immunosuppression|DRUG: golden standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to an Investigational Dengue Type 2 Vaccine
Status: COMPLETED
Conditions: Dengue Virus
Interventions: BIOLOGICAL: Investigational Vaccine for Dengue Virus Subtype 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: Mecamylamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of TG103 in Subjects With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: TG103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer of the Pancreas Screening Study (CAPS 3)
Status: COMPLETED
Conditions: Pancreatic Neoplasm|Peutz-Jeghers Syndrome
Interventions: PROCEDURE: Biopsy, Fine Needle Aspiration (FNA)|DRUG: Secretin (human synthetic) - ChiRhoClin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: ABBV-668
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Sildenafil Citrate|DRUG: Clomiphene Citrate 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Soft Tissue Volume Changes at Small Buccal Dehiscences
Status: RECRUITING
Conditions: Dental Implants
Interventions: PROCEDURE: Soft tissue augmentation with subepithelial connective tissue graft (SCTG)|PROCEDURE: Soft tissue augmentation with xenogenic volume stable collagen matrix (VCXM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Exploratory Efficacy Study of UCMSCs in Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: UCMSCs|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study Evaluating the Safety of the Nasal Guide With Tyrvaya
Status: COMPLETED
Conditions: Dry Eye|Keratoconjunctivitis Sicca
Interventions: COMBINATION_PRODUCT: Nasal Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life After Denture Relining
Status: COMPLETED
Conditions: Quality of Life
Interventions: OTHER: Denture liner Mucopren Soft; Group 1|OTHER: Denture liner Kooliner; Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ATH-1017 in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia of Alzheimer Type
Interventions: DRUG: ATH-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Omega-3 Supplementation for Children With Language Impairments
Status: TERMINATED
Conditions: Language Impairment
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: IDP-121 Lotion|DRUG: IDP-121 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Physical Activity Function Through Enhanced Participation Levels in Animal-Assisted Therapy Programs
Status: WITHDRAWN
Conditions: Stroke|Parkinson's Disease|Muscle Weakness
Interventions: BEHAVIORAL: Canine Animal-Assisted Therapy|BEHAVIORAL: Standard of Care Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-organ Screening for Asymptomatic Ischaemia in Antiphospholipid Syndrome
Status: COMPLETED
Conditions: Antiphospholipid Syndrome
Interventions: DEVICE: MRI|BIOLOGICAL: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Potentiating Rural Investment in Children's Eyecare (PRICE)
Status: COMPLETED
Conditions: Myopia
Interventions: OTHER: Free Glasses|OTHER: Upgrade Glasses 1|OTHER: Upgrade Glasses 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TMC435-TiDP16-C116 - Relative Bioavailability and Food Effect Study
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435 HPMC capsule|DRUG: TMC435 HPMC or gelatin capsule|DRUG: TMC435 HPMC or gelatin capsule|DRUG: TMC435 HPMC or gelatin capsule|DRUG: TMC435 gelatin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Arm Open-Label Multicenter Study of VB-111 in Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: VB-111|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Water Injection Colonoscopy vs Air Insufflation Colonoscopy in Experienced Endoscopists
Status: UNKNOWN
Conditions: Colon Disease;|Rectal Disease;
Interventions: OTHER: Air insufflation|OTHER: Water injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC