pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Toripalimab as Maintenance Therapy in Patients With Driver-gene Negative Advanced NSCLC After First-line Chemotherapy
Status: UNKNOWN
Conditions: NSCLC Stage IV
Interventions: DRUG: Toripalimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Placebo|DRUG: Atorvastatin|DRUG: Non-statin Lipid-Modifying Therapy|OTHER: Diet Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perceptual Learning Improve Visual Function in Patients With Keratoconus
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus, Stable
Interventions: DEVICE: spectacles|DEVICE: perceptual learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: MT-1186
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Valcyte (Valganciclovir) in Pediatric Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation, Cytomegalovirus Infections
Interventions: DRUG: valganciclovir [Valcyte]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-201 in Subjects Ages 16-35 With Peanut Allergy
Status: TERMINATED
Conditions: Peanut Allergy
Interventions: DRUG: CNP-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: lenalidomide, bortezomib and dexamethasone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Fibrosis Quantification Using T1 Mapping Against Histology as Reference and Comparison With Fibrosis Biomarkers
Status: COMPLETED
Conditions: Myocardial Fibrosis
Interventions: DEVICE: RMI|OTHER: myocardial biopsy|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|DRUG: tipifarnib|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Jing Si Herbal Tea for Long-Coronavirus Disease(COVID) Gut-brain Interaction
Status: COMPLETED
Conditions: Healthy Subjects|COVID-19 Pneumonia|Irritable Bowel Syndrome|Functional Gastrointestinal Disorders
Interventions: DIETARY_SUPPLEMENT: Jing Si Herbal Tea Liquid Packet|DIETARY_SUPPLEMENT: Jing Si Herbal Tea Liquid Packet Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CVD 37000: Immunity and Microbiome Studies at Intestinal and Systemic Sites in Ty21a Vaccinated Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Typhoid Vaccination
Interventions: DRUG: Vivotif Typhoid Oral Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Semilunar Coronally Positioned Flap With or Without Enamel Matrix Derivative for the Treatment of Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Semilunar coronally positioned flap|DEVICE: Enamel matrix derivative (Emdogain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of YM178 in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: YM178|DRUG: Placebo|DRUG: tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Optimization of 6% Hydroxyethyl Starch Based Indocyanine Green Near-infrared Fluorescence Navigated Sentinel Lymph Node Biopsy for Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: Near infrared fluorescence navigated sentinel lymph node mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Add on Effect of Solifenacin in Men With Overactive Bladder Symptoms After Tamsulosin Monotherapy for 4 Weeks
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Line Gemcitabine Chemotherapy With Our Without Sunitinib In Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine + Sunitinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resolving Inflammatory Storm in COVID-19 Patients by Omega-3 Polyunsaturated Fatty Acids -
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Omegaven®|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Optimizing Treatment of PegIFN Alfa in HBeAg-negative CHB Patients With Low Level HBsAg
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Talimogene Laherparepvec With Atezolizumab in Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Talimogene laherparepvec|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing NatroxTM Topical Oxygen Therapy to A Placebo in the Management of Non-Healing Leg Ulcers
Status: WITHDRAWN
Conditions: Skin Ulcer Venous Stasis Chronic|Mixed Arteriovenous Leg Ulcer
Interventions: DEVICE: NatroxTM Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: OTHER: leptin, serotonin and adiponectin level|OTHER: leptin,serotonin, adiponectin level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: MicroStent and Standard PTA|DEVICE: Standard PTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Periarticular Parecoxib Sodium for Pain Management in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Unilateral Primary Osteoarthritis of Knee
Interventions: PROCEDURE: parecoxib sodium|PROCEDURE: parecoxib sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Laser Analgesia in Cavity Preparations Using the Er,Cr:YSGG Laser
Status: COMPLETED
Conditions: Tooth Pain
Interventions: DEVICE: Er,Cr:YSGG Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Effects of Omega 3 Fatty Acids in the Context of Cancer Prevention
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Olive oil|OTHER: Olive Oil|OTHER: DHA oil|OTHER: DHA oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib and Fluzoparib in Patients With TNBC
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: SHR-1210 + Apatinib +Fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Stimulation of the Brain in Schizophrenia or Depression
Status: COMPLETED
Conditions: Schizophrenia|Depression|Anhedonia|Avolition
Interventions: DEVICE: dmPFC iTBS|DEVICE: dmPFC Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of NP-120 on Idiopathic Pulmonary Fibrosis and Its Associated Cough
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Ifenprodil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery
Status: UNKNOWN
Conditions: Congenital Heart Disease
Interventions: DRUG: Bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Evidence of Fedratinib Effectiveness in MF
Status: RECRUITING
Conditions: Primary Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Fedratinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ph Ib/BGJ398/Cervix and Other Solid Tumors
Status: WITHDRAWN
Conditions: Cancer of Cervix|Tumors
Interventions: DRUG: BGJ398|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSD170301: An Unblinded, Parallel, Randomized Study to Assess Nicotine Uptake in Smokers From Four Different Electronic Cigarettes
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: FT21039|OTHER: FT21041|OTHER: FT21044|OTHER: FT21042
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Preliminary Efficacy of L-arginine in Severe Falciparum Malaria
Status: SUSPENDED
Conditions: Severe Falciparum Malaria
Interventions: DRUG: L-arginine hydrochloride|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment
Status: RECRUITING
Conditions: MGMT-Methylated Glioblastoma|Recurrent Glioblastoma, IDH-Wildtype|Recurrent MGMT-Methylated Glioblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|DRUG: Selinexor|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation by Iberis MultiElectrode Renal Denervation System in Patients With Primary Hypertension
Status: UNKNOWN
Conditions: Primary Hypertension
Interventions: DEVICE: Renal Denervation System (AngioCare)|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Common Eye Diseases
Status: UNKNOWN
Conditions: Uveitis|Diabetic Retinopathy|Age-related Macular Degeneration|Polypoidal Choroidal Vasculopathy|VKH Syndrome|Behçet Disease
Interventions: OTHER: Collection of blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Volixibat (SHP626) in the Treatment of Adults With Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DRUG: SHP626|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Ropinirole PR/XR Tablets in Monotherapy for Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Ropinirole prolonged release/extended release(PR/XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iNtrAcranial PreSsurE in Intensive Care (ICU) (SynapseICU)
Status: COMPLETED
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage|Intracerebral Hemorrhage
Interventions: PROCEDURE: intracranial pressure monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Different Methods of Delivering Local Analgesia During Intra-articular Corticosteroid Injections in Children With Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure
Status: COMPLETED
Conditions: Thrombocytopenia Associated With Liver Disease
Interventions: DRUG: avatrombopag (lower baseline platelet count)|DRUG: placebo (lower baseline platelet count)|DRUG: avatrombopag (higher baseline platelet count)|DRUG: placebo (higher baseline platelet count)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency in the Treatment of Barrett's Oesophagus
Status: COMPLETED
Conditions: Esophageal Neoplasm
Interventions: PROCEDURE: Oesophagectomy|DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rebamipide in Patients With Active Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rebamipide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EEG-based Depth of Anesthesia-monitoring, Effects on Dosage and Cognition
Status: RECRUITING
Conditions: Postoperative Complications|Delayed Emergence From Anesthesia|Cognitive Dysfunction
Interventions: DEVICE: Bilateral Bispectral Index and EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Irinotecan in Treating Patients With Refractory Solid Tumors and Liver Dysfunction
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor|Chemotherapy|Liver Dysfunction|Neoplasms, Solid Tumor
Interventions: DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium.
Status: TERMINATED
Conditions: Non Cystic Fibrosis Bronchiectasis
Interventions: DRUG: CMS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Shotgun Sequencing in Diagnosing Febrile Neutropenia in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Febrile Neutropenia
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intelligent Customer-driven Solution for Pediatric Surgery Care for Parents and Their Children Undergoing Circumcision
Status: UNKNOWN
Conditions: Circumlocution|Children|Surgery|Parents
Interventions: OTHER: ICory-Circumcision|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Trial of 24-Week Versus 48-Week Courses of Peginterferon Plus Ribavirin for Patients With Genotype 1 Hepatitis C and IL28B CC Polymorphism
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa2a|DRUG: Ribavirin|DRUG: Peginterferon alfa2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelialized ePTFE Graft by Nanobiotechnology
Status: COMPLETED
Conditions: The Apparatus for Processing the Tubular Graft Modification Will be Designed and Evaluated.|The On-site Capturing of the Endothelial (Progenitor) Cells by Peptide-mediated Selective Adhesion in Vitro and in Vivo Will Also be Elucidated.|The Patency Rate of ITRI-made Artificial Blood Vessels Will be Evaluated by the Porcine Animal Model.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma of Head and Neck|Recurrent Squamous Cell Carcinoma of the Head and Neck|Metastatic Cancer|Metastatic Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: Ozuriftamab Vedotin|BIOLOGICAL: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PVT-1 Treatment in Patients With Advanced Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Advanced Cancer|Refractory Cancer
Interventions: DRUG: PVT-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training in Women With Cardiac Devices
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: moderate-intensity continuous exercise training (MICT) group|BEHAVIORAL: high-intensity interval training (HIIT) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of First Aid Blended Learning Training on Learning Outcomes and Helping Behaviour of Adult Laypeople in Rwanda
Status: COMPLETED
Conditions: Emergencies|Injuries|Illness Physical
Interventions: OTHER: First aid training with blended learning approach|OTHER: First aid training with face-to-face approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 100% VS 80% Of Pegasys In Koreans With Chronic Hepatitis C (CHC)
Status: COMPLETED
Conditions: Sustained Virologic Response|IL28B Polymorphism
Interventions: DRUG: peginterferon alfa 2a (pegasys)|DRUG: peginterferon alfa-2a (pegasys)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of the FAST (Focused Abdominal Scan for Trauma) Scan by Paramedics in Mass Casualty Incidents
Status: COMPLETED
Conditions: Mass Casualty
Interventions: PROCEDURE: SonoSite Ultrasound|PROCEDURE: SonoSite Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Knee Mobilisation on Joint Position Sense and Tissues
Status: ACTIVE_NOT_RECRUITING
Conditions: Manual Therapy|Knee
Interventions: OTHER: Pulse traction|OTHER: Continuous traction|OTHER: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reverse Shoulder Prosthesis Study
Status: COMPLETED
Conditions: Rotator Cuff Arthropathy|Failed Total Shoulder|Failed Hemi-arthroplasty
Interventions: DEVICE: Reverse Shoulder Prosthesis|DEVICE: Reverse Shoulder Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-3281 in Healthy and Hepatitis C Infected Male Participants (MK-3281-002)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MK-3281|DRUG: Placebo to MK-3281
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colecalciferol as an Add-on Treatment to Subcutaneously-Administered Interferon-beta-1b for Treatment of Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: colecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917838|DRUG: valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Paired Psoriasis Lesion, Comparative, Study to Evaluate MOL4239 in Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: MOL4239|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation
Status: COMPLETED
Conditions: Neoplasms|Advanced Solid Tumors|Non-small Cell Lung Cancer|Colorectal Cancer
Interventions: DRUG: JNJ-74699157
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Topical 0.5% Ivermectin Lotion for the Treatment of Head Lice Infestation in Filipinos
Status: COMPLETED
Conditions: Pediculosis Capitis
Interventions: DRUG: 0.5% Ivermectin lotion|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation in Multiple Fracture Ribs
Status: UNKNOWN
Conditions: Mechanical Ventilation
Interventions: DEVICE: Biphasic Intermittent Positive Airway Pressure (BIPAP)|DEVICE: Airway Pressure Release Ventilation (APRV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prophylactic and Therapeutic Anticoagulants in Egyptian Patients With COVID-19
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection|Hypercoagulability
Interventions: DRUG: Enoxaparin|DRUG: Enoxaparin|DRUG: Rivaroxaban|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Apixaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-thyroidectomy Dysphagia: An International Multicentric CONSORT - Compatible RCT
Status: UNKNOWN
Conditions: Dysphagia, Esophageal|Dysphagia, Oral Phase|Dysphagia Comes and Goes|Thyroiditis|Thyroid Cancer|Thyroid Neoplasms|Thyroid Goiter|Thyroid Nodule (Benign)
Interventions: PROCEDURE: Total thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trail to Evaluate the Efficacy and Safety of DWJ1451
Status: UNKNOWN
Conditions: Hypertension, Dyslipidemia
Interventions: DRUG: Amlodipine/Olmesartan 10/40mg (Combination drug), Ezetimibe/Rosuvastatin 10/20mg(Combination drug)|DRUG: Olmesartan 40mg, Ezetimibe/Rosuvastatin 10/20mg(Combination drug)|DRUG: Amlodipine/Olmesartan 10/40mg (Combination drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Bone Changes in Post-menopausal Osteoporotic Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DEVICE: Dental implant placement (Straumann® Bone Level Tapered, BLT, Roxolid® SLActive®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)
Status: TERMINATED
Conditions: Metastatic Gastric Cancer
Interventions: DRUG: Panobinostat (LBH589)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Pattern and Prognosis of Multiple Myeloma Patients With Myocardial Amyloidosis Were Evaluated by NMR Based Metabolomics
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Myeloma|Amyloidosis Cardiac
Interventions: DEVICE: NMR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tumescent Stretching Measurement Technique
Status: UNKNOWN
Conditions: To Try to Eliminate Frequencies of Insertions in Order to Arrive to Adequate Size of Implanted Penile Prosthesis
Interventions: PROCEDURE: Tumescent Stretching Measurement Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Non-surgical Periodontal Therapy in the Management of Plaque Psoriasis.
Status: UNKNOWN
Conditions: Psoriasis Vulgaris|Psoriasis|Periodontitis
Interventions: OTHER: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL
Status: COMPLETED
Conditions: Aphakia|Presbyopia
Interventions: DEVICE: Alcon Fluid Accommodating Intraocular Lens|OTHER: Top Con Autorefractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time
Status: UNKNOWN
Conditions: Dysphagia|GERD|Abdominal Pain
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Trastuzumab, HER2 Positive Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Trastuzumab|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-comparative Study of Treatment With Induction Chemotherapy With Cisplatin and Gemcitabine Followed by Chemoradiation or Definitive Chemoradiation in Invasive Locally Advanced Carcinomas of Uterine Cervix.
Status: UNKNOWN
Conditions: Patients Diagnosed With Advanced Carcinoma of Uterine Cervix t
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: cisplatin|RADIATION: Radiotherapy|RADIATION: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exergames-acceptance and Commitment Therapy Program for Treatment of Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Exergames-acceptance and commitment therapy (e-ACT)|BEHAVIORAL: Acceptance and commitment therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Ephedrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of ABCB1 Polymorphisms on Plasma Concentrations of New Oral Anticoagulants in Case of Serious Adverse Events
Status: COMPLETED
Conditions: Anticoagulants|Thromboembolism|Hemorrhage
Interventions: OTHER: Measurement of Plasma Concentrations of NOACs|GENETIC: Identification of ABCB1 polymorphisms coding for P-gp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Genicular Nerves Chemical Neurolysis on the Quality of Life of Patients With Advanced Knee Osteoarthritis.
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Osteoarthritis
Interventions: DRUG: 0.9% Sodium chloride|DRUG: 95% ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis
Status: TERMINATED
Conditions: Liver Cirrhoses
Interventions: DRUG: Placebo oral tablet|DRUG: Atorvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Celecoxib in Treating Patients With Stage IIIB or Stage IV Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: celecoxib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, and Pharmacokinetics Study of HEC113995 PA•H2O Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: HEC113995 PA•H2O tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))
Status: TERMINATED
Conditions: Inflammation|Perioperative Morbidity
Interventions: DRUG: Dexamethasone Sodium Sulfate|DRUG: Insulin|DRUG: anesthesia management|OTHER: Dexamethasone - placebo|OTHER: Insulin - Placebo|OTHER: Anesthesia management -Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Capivasertib film-coated tablet, 200 mg|DRUG: [14C]AZD5363 (Capivasertib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics
Status: COMPLETED
Conditions: Post-operative Pain|Quadriceps Muscle Strength
Interventions: PROCEDURE: Adductor Canal Block|PROCEDURE: Femoral Nerve Block|DEVICE: Ultrasound|DEVICE: Stimuplex A needle|DRUG: local anaesthetic injection|DRUG: Steroid Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Controlled Study to Evaluate the Efficacy of Allogeneic MesenCure for the Treatment of Patients With ARDS
Status: NOT_YET_RECRUITING
Conditions: ARDS
Interventions: BIOLOGICAL: MesenCure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)
Status: NOT_YET_RECRUITING
Conditions: Moderate to Severe Alzheimer's Disease
Interventions: DRUG: GV1001 Placebo|DRUG: GV1001 1.12mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EchoTip AcuCore Post-Market Clinical Study
Status: RECRUITING
Conditions: Adenocarcinoma|Neuroendocrine Tumors|Hepatocellular Carcinoma|Cholangiocarcinoma|Malignant Lymphoma|Metastasis|Chronic Pancreatitis|Autoimmune Pancreatitis
Interventions: DEVICE: EchoTip AcuCore
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion.
Status: COMPLETED
Conditions: Brain Concussion|Post-Concussion Syndrome
Interventions: OTHER: Enhanced Usual Care (EUC)|BEHAVIORAL: EUC + Early intervention programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of CSRT-led Telephone Follow-up on ESAS Scores in Patients Who Have Been Treated With Lung SBRT
Status: WITHDRAWN
Conditions: Lung Cancer, Anxiety Post SBRT
Interventions: OTHER: CSRT led telephone follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: End Tidal CO2 and Masks: Is There a Correlation?
Status: COMPLETED
Conditions: End Tidal Carbon Dioxide (ETCO2)
Interventions: OTHER: Baseline measure of ETCO2 without mask|OTHER: Baseline ETCO2 with mask|OTHER: ETCO2 after 200 meter walk with mask|OTHER: ETCO2 after 200 meter walk without mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Crowdsourcing to Reduce HIV Stigma Among Adolescents and Young Adults in Kazakhstan
Status: COMPLETED
Conditions: Stigma, Social|HIV Testing
Interventions: BEHAVIORAL: Digital Crowdsourced Intervention to Reduce HIV Stigma among Adolescents and Young Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Palliative Low-Dose Involved-Field Radiation Therapy for Recurrent Advanced Follicular Lymphoma
Status: RECRUITING
Conditions: Recurrent Follicular Lymphoma
Interventions: RADIATION: Low-dose involved-field radiotherapy|RADIATION: Involved-field radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bevacizumab (Avastin®) Combined to Weekly Paclitaxel Followed by Bevacizumab (Avastin®) Alone in Patients With Relapsed Ovarian Sex-cord Stromal Tumours (ALIENOR)
Status: COMPLETED
Conditions: Ovarian Sex-cord Stromal Tumor
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tong-Luo-Qu-Tong Plaster for KOA: a Randomised, Double-blind, Parallel Positive Control, Multi-center Clinical Trial
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Chronic Musculoskeletal Disease
Interventions: DRUG: Tong-Luo-Qu-Tong Plaster|DRUG: Qi-Zheng-Xiao-Tong Plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Copanlisib on Metformin Pharmacokinetics and Pharmacodynamics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Copanlisib (Aliqopa, BAY80-6946)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Autonomic Nervous Activity and Blood Pressure After Anesthesia Induction: Remimazolam Versus Propofol
Status: COMPLETED
Conditions: General Anesthetics
Interventions: DRUG: Anesthesia induction with propofol|DRUG: Anesthesia induction with remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lurbinectedin Monotherapy in Patients With Progressive Malignant Pleural Mesothelioma.
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma, Advanced
Interventions: DRUG: Lurbinectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA PET in the Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms|Metastases|PSMA-PET
Interventions: DIAGNOSTIC_TEST: PSMA PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS) With Refractory Anemia (RA)|Severe Aplastic Anemia (SAA)
Interventions: BIOLOGICAL: Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Yoga on Loneliness, Anger and Salivary Cortisol Levels in Visually Impaired Individuals
Status: ENROLLING_BY_INVITATION
Conditions: Nursing Caries|Laughter|Visual Impairment|Loneliness|Anger
Interventions: OTHER: Laughter yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgical Ergonomics Education During Minimally Invasive Gynecologic Skills Training
Status: NOT_YET_RECRUITING
Conditions: Work-related Injury|Work Related Upper Limb Disorder|Surgery|Educational Problems
Interventions: OTHER: Ergonomics Knowledge|OTHER: Ergonomics Feedback/Guided Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With Clozapine
Status: COMPLETED
Conditions: Schizophrenia|Auditory Hallucinations
Interventions: PROCEDURE: Active rTMS x sham (placebo) rTMS|PROCEDURE: sham rTMS|PROCEDURE: (1Hz) rTMS applied over the left temporoparietal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CCCG-HD-2018 for Children and Adolescents With Newly Diagnosed Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: OTHER: Combined chemotherapy with or without involved-field radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of Use of the "KONTACT PERIO LEVEL" Transgingival Titanium Dental Implant
Status: COMPLETED
Conditions: Tooth Loss|Partially Edentulous Maxilla|Partially Edentulous Mandible
Interventions: DEVICE: KONTACT PERIO LEVEL (KPL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Versus Late Intubation Trial in Physician Manned Emergency Medical Services
Status: WITHDRAWN
Conditions: Trauma|Craniocerebral Trauma|Intracerebral Hemorrhage|Seizures|Unconsciousness
Interventions: PROCEDURE: Early Intubation|PROCEDURE: Late intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Trikafta|DRUG: symdeko/Trikafta|DRUG: Ivacaftor/Trikafta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Individualized Homeopathic Remedies on Migraine: a Randomized, Triple-blind, Placebo Controlled Study.
Status: UNKNOWN
Conditions: Migraine
Interventions: OTHER: Individualized Homeopathic Remedy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 5-FU Versus MTX+5-FU in Gastric Cancer With Peritoneal Metastasis
Status: COMPLETED
Conditions: Gastric Cancer|Neoplasm Metastasis
Interventions: DRUG: 5-FU continuous infusion|DRUG: MTX + 5-FU sequential therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial in Men With Hormone Sensitive Oligometastatic Prostate Cancer
Status: WITHDRAWN
Conditions: Hormone Sensitive Oligometastatic Prostate Cancer
Interventions: PROCEDURE: Radical prostatectomy|RADIATION: HDR (19Gy) or SBRT (35-40Gy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Prevention and Management for Perioperative Hypothermia and Its Effect on Patients Outcome
Status: UNKNOWN
Conditions: Hypothermia; Anesthesia
Interventions: COMBINATION_PRODUCT: high risk warm|COMBINATION_PRODUCT: moderate risk warm|COMBINATION_PRODUCT: low risk warm|OTHER: passive warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A to Treat Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: MT10109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Safety of 2 Doses of Retigabine Immediate Release (900 mg/Day and 600 mg/Day) Used as Adjunctive Therapy in Adult Asian Subjects With Drug-resistant Partial-onset Seizures
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Retigabine 900mg/day|DRUG: Retigabine 600mg/day|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of UCB and MSCs in Children With CP: ACCeNT-CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Infusion of allogeneic umbilical cord blood|BIOLOGICAL: Infusion of MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation of the Thalamus to Ameliorate Persistent Disfluency
Status: NOT_YET_RECRUITING
Conditions: Persistent Developmental Stutter|Childhood-Onset Fluency Disorder (Stuttering)
Interventions: DEVICE: System On|DEVICE: System off
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating the Safety and Efficacy of BinD19 Treatment in R/R ALL and Lymphoma Subjects
Status: UNKNOWN
Conditions: Relapsed B-cell Acute Lymphoblastic Leukemia|Refractory B-cell Acute Lymphoblastic Leukemia|Relapsed／Refractory B-cell Lymphoma
Interventions: BIOLOGICAL: BinD19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT