pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Event Rate and Effects of Stimulants in ADHD
Status: WITHDRAWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: LDX.|DRUG: sugar pill|DEVICE: computer task (Go/No-Go task)|DEVICE: EEG|DEVICE: pupil size measurements (by using eye tracking)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study To Assess The Safety And Tolerability Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin for Peripheral Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Microvascular Dysfunction
Interventions: DRUG: Participants receive 10mg Empaglifozin once daily on prescription from their treating physician. This is not an intervention in this trial, but part of their normal HFpEF treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Undifferentiated Leukemia|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: GTI-2040|PROCEDURE: pharmacological study|PROCEDURE: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Pharmacist and Student Pharmacists on Medication Adherence in Community Pharmacy Setting in Underserved Population
Status: WITHDRAWN
Conditions: Diabetes|Medication Non Adherence|Blood Pressure|Pharmacist-Patient Relations
Interventions: OTHER: Pharmacist and pillpack intervention|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Effects of Selpercatinib in Hepatically Impaired Participants and Healthy Participants
Status: COMPLETED
Conditions: Healthy|Hepatic Impairment
Interventions: DRUG: Selpercatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effects of Plx on Bioparametric Measurements.
Status: COMPLETED
Conditions: Quality of Life|Antidepressive Agents|Depression, Anxiety|Sleep Initiation and Maintenance Disorders|Body Composition|Stress, Psychological
Interventions: DIETARY_SUPPLEMENT: PLX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Verofilcon A Daily Disposable Lenses to Somofilcon A Daily Disposable Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: somofilcon A|DEVICE: verofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI)
Status: UNKNOWN
Conditions: Venous Insufficiency
Interventions: DRUG: Flavonid|DRUG: Daflon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: International Study to Evaluate a Navigation Program for Older People With Cancer and Their Family Caregivers (EU NAVIGATE Study)
Status: NOT_YET_RECRUITING
Conditions: Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
Interventions: BEHAVIORAL: NavCare-EU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Number of Meals on Metabolism After Weight Loss Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: OTHER: Solid Meal|OTHER: Liquid Meal|DRUG: Acetaminophen|OTHER: Single, 600 kcal meal|OTHER: Multiple, 200 kcal meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nobel Procera Crown Shaded Zirconia and NobelProceraTM Full Contour Crown IPS e.Max CAD
Status: TERMINATED
Conditions: Partial Edentulism
Interventions: DEVICE: NobelProcera Crown Shaded Zirconia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Salience Level (Expt 1.1)
Status: RECRUITING
Conditions: Basic Science: Visual Attention in Healthy Participants|Basic Science: Neural Representations of Location|Attention
Interventions: OTHER: Stimulus properties: salience-defining feature|OTHER: Stimulus properties: magnitude of salience
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety, Tolerability, and Reactogenicity of the Baiya SARS-CoV-2 Vax 2 Vaccine for COVID-19 Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: 25 Baiya SARS-CoV-2 Vax 2|BIOLOGICAL: 50 Baiya SARS-CoV-2 Vax 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adaptation and Implementation of an ASD Executive Functioning Intervention in Children's Mental Health Services
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Mental Health Disorder|Executive Dysfunction
Interventions: BEHAVIORAL: Unstuck and on Target (UOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Safety and Pharmacokinetics of Montelukast (MK-0476) in the Treatment of Japanese Pediatric Participants With Perennial Allergic Rhinitis (MK-0476-520)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Montelukast Oral Granules (OG)|DRUG: Montelukast Chewable Tablets (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab With Stereotactic Ablative Radiotherapy in Patients With Metastatic Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Patients With Metastatic Tumours (Colorectal Cancer, Non-small Lung Cancer, Renal Cell Carcinoma or Sarcoma )
Interventions: DRUG: Anti-PD-L1 antibody atezolizumab|PROCEDURE: SABR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing KS Versus TS for Ovedenture
Status: NOT_YET_RECRUITING
Conditions: Dental Implant|Dental Implant-Abutment Design|Edentulous Jaw
Interventions: DEVICE: Implant placement with 3.5 mm diameter KS implants.|DEVICE: Implant placement with 3.5 mm diameter TS implants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aqueous Flare of a Hydrophobic Acrylic Single-piece Open-loop IOL With Modified Material Surface Properties
Status: COMPLETED
Conditions: Cataract|Diabetes|Pseudoexfoliation Syndrome
Interventions: DEVICE: Polylens EC-HY10-PAL (coated)|DEVICE: Polylens EC-Y10-PAL (uncoated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Adrenal Insufficiency|Excess Androgen|Congenital Adrenal Hyperplasia (CAH)
Interventions: DRUG: Hydrocortisone (Solucortef)|DEVICE: Insulin pump (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Efficacy and Safety Study of Fostamatinib in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Fostamatinib Disodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of sPTB With Early Cervical Pessary Treatment in Women at High Risk for PTB
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth|Premature Birth
Interventions: DEVICE: cervical pessary|OTHER: Control-Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Diabetes Improvement in Medical Therapy Versus SADJB Study
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Overweight
Interventions: PROCEDURE: SADJB-SG group|PROCEDURE: IMT group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Jejunal to Ileal Diversion Endoscopic Procedure (Side-to-Side Anastomosis)
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Jejunal to Ileal Diversion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
Status: RECRUITING
Conditions: Healthy|Enteric Hyperoxaluria
Interventions: BIOLOGICAL: FB-001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Residual Hypermetropic Refraction on Pseudophakic Patients Using Allogenic Fresh Myopic Lenticule
Status: ACTIVE_NOT_RECRUITING
Conditions: Pseudophakia|Hypermetropia|Myopia
Interventions: OTHER: FRESH CORNEAL MYOPIC LENTICULE IMPLANTATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods.
Status: COMPLETED
Conditions: Nicotine Dependence|Nicotine Dependence, Cigarettes|Tobacco Use|Tobacco Smoking
Interventions: OTHER: JUUL Virginia Tobacco flavored 5.0% ENDS|OTHER: PMI iQOS Heat sticks|OTHER: Reynolds VUSE Solo ENDS - Original|OTHER: Imperial MyBlu ENDS - Original|OTHER: Altria MarkTen ENDS - Bold Classic|OTHER: MLV PHIX ENDS - Original Tobacco|OTHER: NJOY Daily EXTRA ENDS - Rich Tobacco|OTHER: Altria Marlboro combustible cigarette - Red
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FREEDOM: "Pilot Study of the Feasibility and Safety of Resuming Early Walking After Manual Compression in Patients Treated for Peripheral Artery Disease by Endovascular Technique Involving Retrograde Femoral Puncture"
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Manual puncture point compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder
Status: UNKNOWN
Conditions: Depressive Disorder, Major
Interventions: DRUG: Mitizodone Phosphate tablets|DRUG: Placebo-matching tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Sufentanil
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sufentanil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"
Status: COMPLETED
Conditions: Scar
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of QGE031 in Japanese Atopic Male Subjects
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: QGE031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Endoscopic Surgery and Exercise Therapy in Patients With Longstanding Achilles Tendinopathy
Status: TERMINATED
Conditions: Tendinopathy
Interventions: PROCEDURE: endoscopic surgery|BEHAVIORAL: physiotherapy and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saccharomyces Cerevisiae on the Improvement of Gastro-intestinal Disorders Associated to IBS With C Phenotype
Status: COMPLETED
Conditions: Constipation-predominant Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Saccharomyces cerevisiae CNCM I-3856|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: Platelet Rich Plasma (Preparation Rich in Growth Factors)|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Very Low Frequency Magnetic Fields Versus the Supplement "Xinepa" in the Treatment of the Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: ELF|OTHER: Xinepa®|OTHER: Placebo Xinepa®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Full-Thickness Skin Defects in Adults and Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Wound
Interventions: BIOLOGICAL: EHSG-KF|BIOLOGICAL: STSG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: monosialotetrahexosylganglioside Sodium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Relative Bioavailability of Ibuprofen in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen extrudate|DRUG: Ibuprofen lysinate|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DEVICE: Self-injector pen device (OptiClik®)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis (TB)
Interventions: BIOLOGICAL: MTBVAC|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia
Status: COMPLETED
Conditions: Childhood Acute Promyelocytic Leukemia (M3)|Childhood Atypical Teratoid/Rhabdoid Tumor|Childhood Burkitt Lymphoma|Childhood Chronic Myelogenous Leukemia|Childhood Diffuse Large Cell Lymphoma|Childhood Immunoblastic Large Cell Lymphoma|Juvenile Myelomonocytic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent/Refractory Childhood Hodgkin Lymphoma|Relapsing Chronic Myelogenous Leukemia|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: vorinostat|DRUG: isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia
Status: ENROLLING_BY_INVITATION
Conditions: Beta-Thalassemia
Interventions: DRUG: BRL-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors
Status: UNKNOWN
Conditions: Ischemic White Matter Disease|Transient Ischemic Attack|Mild Stroke|Stroke Risk
Interventions: BEHAVIORAL: Executive Function Training Program|BEHAVIORAL: Psychoeducational Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial of an Integrative Intervention to Improve Critically Ill Patients' Delirium and Related Outcomes
Status: RECRUITING
Conditions: Delirium
Interventions: OTHER: RGI & Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects
Status: TERMINATED
Conditions: Muscular Dystrophies
Interventions: DRUG: Drisapersen|DRUG: Drisapersen|DRUG: Drisapersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rifaximin in Patients With Gastroesophageal Variceal Bleeding
Status: COMPLETED
Conditions: Cirrhosis|Esophageal and Gastric Varices|Gastrointestinal Hemorrhage
Interventions: DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Frailty With a Rigorous Ambulation Intervention in Lung Transplant Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Transplant-Related Disorder|Frail Elderly Syndrome|Sarcopenia|Lung Graft Dysfunction|Mobility Limitation
Interventions: OTHER: Ambulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of MT921 in Subjects With Moderate to Severe Submental Fat
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: MT921|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression
Status: TERMINATED
Conditions: Kidney Transplant Failure and Rejection
Interventions: DRUG: Tacrolimus (TAC)|DRUG: Sirolimus|DRUG: Alemtuzumab|DRUG: Mycophenolate mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Study With an Extension Examining the Safety and Efficacy of Alefacept in Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Alefacept|DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypocaloric Mediterranean Diet or Physical Activity to Lower Cardiometabolic Risk
Status: RECRUITING
Conditions: Overweight or Obesity|Obesity, Abdominal|Hypertension
Interventions: BEHAVIORAL: Physical activity|BEHAVIORAL: Hypocaloric Mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Comparison of 2 Daily Disposable Toric Soft Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors|Astigmatism
Interventions: DEVICE: Verofilcon A toric contact lenses|DEVICE: Stenfilcon A toric contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Influence of Fortified Pomegranate Juice (Punica Granatum) on Seasonal Influenza and Swine Flu Patients
Status: UNKNOWN
Conditions: Influenza A|Swine Flu
Interventions: DIETARY_SUPPLEMENT: Pomegranate juice|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer
Status: UNKNOWN
Conditions: Colon Cancer|Esophageal Carcinoma|Pancreatic Cancer|Prostate Cancer|Gastric Cancer|Hepatic Carcinoma
Interventions: BIOLOGICAL: CAR-T cell immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Patients With Diabetes Mellitus Using Either Insulin or Oral Antidiabetic Drug In Terms Of Difficult Laryngoscopy
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: difficult laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of the Bioabsorbable Activa IM-Nail™ in Pediatric Diaphyseal Forearm Fractures
Status: RECRUITING
Conditions: Fracture Fixation, Intramedullary|Forearm Fracture|Fracture Healing|Child, Only|Implant Complication
Interventions: DEVICE: Activa IM-Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in the Treatment of Residual Chronic Subdural Hematoma -2
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Tranexamic Acid 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Glycemia in Women at Risk For Persistent Hyperglycemia
Status: RECRUITING
Conditions: Gestational Diabetes
Interventions: DIAGNOSTIC_TEST: 2-hour 75-g oral glucose tolerance test and Dexcom G6 Pro continuous glucose monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Investigate Efficacy of FOL-005 on Hair Growth on Scalp Skin
Status: COMPLETED
Conditions: Androgenic Alopecia
Interventions: DRUG: FOL-005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Functional Mitral Regurgitation in Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Mitral Regurgitation Functional
Interventions: OTHER: Catheter Ablation and M-TEER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Hemoglobin Level Depending on the Comorbidity Index in Chronic Kidney Disease (CKD) Participants Not in Dialysis Treated With Methoxy Polyethylene Glycol-Epoetin Beta (COMETE)
Status: COMPLETED
Conditions: Renal Anemia of Chronic Kidney Disease
Interventions: DRUG: Methoxy Polyethylene Glycol-Epoetin Beta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoxygenation for Tracheal Aspirations in Intensive Care
Status: NOT_YET_RECRUITING
Conditions: ICU Patients Under Invasive Mechanical Ventilation
Interventions: PROCEDURE: Experimental : Patients without additional preoxygenation|PROCEDURE: Active Comparator : Patients with additional preoxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Favipiravir|DRUG: Favipiravir|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Ascending Doses of Niclosamide (UNI911 INHALATION) in Healthy Volunteers
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: UNI911 inhalation 1% and intranasal spray 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy Plus PSC-833 in Treating Children With Refractory or Relapsed Acute Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: valspodar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetics of Fentanyl in Patients Undergoing Living Donor Liver Transplantation
Status: COMPLETED
Conditions: Living Donor Liver Transplantation
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VATS Versus Thoracotomy for Pulmonary Hydatid Disease
Status: COMPLETED
Conditions: Pulmonary Hydatid Cyst
Interventions: PROCEDURE: VATS approach|PROCEDURE: Thoracotomy approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Evaluation Of Fx-1006a In Patients With V122i Or Wild-Type Transthyretin (TTR) Amyloid Cardiomyopathy
Status: COMPLETED
Conditions: ATTR-CM|TTR-CM
Interventions: DRUG: tafamidis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effect of Food on the Absorption of an Oral Testosterone Undecanoate Formulation
Status: COMPLETED
Conditions: Male Hypogonadism
Interventions: DRUG: Oral testosterone undecanoate (containing 300 mg T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of of a Lipid Emulsion on Inflammatory Response and Hepatic Function
Status: COMPLETED
Conditions: Inflammatory Response|Hepatic Function
Interventions: DRUG: SMOFlipid®|DRUG: 2-ClinOleic 20%®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sexual Function in Patients Suspected of Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms|Sexual Dysfunction, Physiological|Sexual Dysfunctions, Psychological|Erectile Dysfunction|Hematuria
Interventions: OTHER: EORTC QLQ-C30 and EORTC BLS-24 questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of 3 Day Preoperative Immunonutrition in Well-nourished Patients With Gastrointestinal (GI) Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Gastrointestinal Cancer
Interventions: DIETARY_SUPPLEMENT: Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine vs Ropivacaine for TAPBs
Status: RECRUITING
Conditions: Abdominal Tumor|Postoperative Analgesia|Liposomal Bupivacaine|Ropivacaine
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Abacavir/Lamivudine Versus Emtricitabine/Tenofovir Both In Combination With Lopinavir/Ritonavir For The Treatment Of HIV
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: emtricitabine/tenofovir|DRUG: abacavir/lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Electronic Reminder Module to Enhance Postoperative Nausea and Vomiting Prophylaxis
Status: WITHDRAWN
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: Postoperative nausea and vomiting (PONV) reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Using an Integrated Consent Model to Compare Two Standard of Care Regimens for the Management of Hypomagnesemia From Anti-Cancer Therapies
Status: COMPLETED
Conditions: Hypomagnesemia
Interventions: OTHER: Magnesium Oxide|OTHER: Magnesium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-In-Human Study Of Orally Administered CoV2-OGEN1 In Healthy Subjects
Status: COMPLETED
Conditions: SARS-CoV-2 (COVID-19)
Interventions: DRUG: Orally Suspension of CoV2-OGEN1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osteoporotic Vertebral Compression Fractures: Can Kyphoplasty Improve Lung Function? A Prospective Evaluation
Status: UNKNOWN
Conditions: Osteoporotic Vertebral Compression Fractures|Lung Function
Interventions: PROCEDURE: Radiofrequency Kyphoplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Megestrol and Exercise in Treating Patients With Cancer-Related Weight Loss
Status: COMPLETED
Conditions: Cachexia|Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: megestrol acetate|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enabling Women with Parkinson's Disease to Identify and Better Manage Hormonal Triggers of Parkinsonian Symptoms
Status: NOT_YET_RECRUITING
Conditions: Digital Technology|Mobile Application|Motor Fluctuations|Oestrogen|Parkinson Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986322|DRUG: Rosuvastatin|DRUG: Metformin|DIETARY_SUPPLEMENT: Glucose|DRUG: Methotrexate|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Extend Efficacy and Safety of SHR-1819 Injection in Adult Patients With Moderate to Severe Atopic Dermatitis
Status: ENROLLING_BY_INVITATION
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: SHR-1819 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Lenvatinib in Clear Cell Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Clear Cell Carcinoma|Gynecologic Cancer
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRT and CBT in Sexual Assault Victims With PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for PTSD|BEHAVIORAL: Imagery Rehearsal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onlıne Yoga Compared to Face-To-Face Yoga on Dıaphragm Thıckness, Body Balance and Psychosocıal Status
Status: COMPLETED
Conditions: Mind-Body Therapies|Yoga|Telerehabilitation
Interventions: OTHER: Online yoga exercise|OTHER: Face-to-face yoga exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
Status: COMPLETED
Conditions: Liver Cancer|Anxiety Disorder|Depression|Small Cell Lung Cancer|Extrahepatic Bile Duct Cancer|Malignant Mesothelioma|Pancreatic Cancer|Esophageal Cancer|Gastric Cancer|Non-small Cell Lung Cancer
Interventions: OTHER: Early palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Antenatal Perineal Massage in Reducing Postpartum Morbidities
Status: RECRUITING
Conditions: Perineum; Injury|Anal Incontinence|Urinary Incontinence
Interventions: OTHER: Antenatal perineal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Colorectal Cancer (CRC) Cetuximab Elderly Frail
Status: TERMINATED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Cetuximab|DRUG: 5-fluorouracil|DRUG: leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Renastart Formula Supplementation in Children With Acute Kidney Injury in Maintaining Normal Serum Electrolytes Levels
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DIETARY_SUPPLEMENT: Renastart formula|DRUG: calcium carbonate (phosphorus binder) with / or sodium polystyrene sulfonate (potassium binder) with dosage 0.5-1mg/kg/day orally.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Effects of Dressing With Honey and EUSOL
Status: COMPLETED
Conditions: Necrotizing Fascitis|Wound Infection
Interventions: DRUG: Honey|COMBINATION_PRODUCT: EUSOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Study of Social Representation of Platelet Transfusion in Patients Followed for Advanced Hematological Malignancies (R-PLQ)
Status: COMPLETED
Conditions: Platelet Transfusion|Hematological Malignancy|Palliative Care
Interventions: OTHER: multi method questionary (developped by De Rosa, in 1995 and 2014)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Renal Autotransplantation; Case Series
Status: ENROLLING_BY_INVITATION
Conditions: Renal Vascular Disease|Nutcracker Syndrome, Renal|Pelvic Trauma|Loin Pain-Hematuria Syndrome|Renal Tumor|Congestion, Venous
Interventions: PROCEDURE: Pre-Operative Information|PROCEDURE: Intra-Operative Data|OTHER: Post-Operative Data (up to discharge)|OTHER: Short-Term Follow-Up Data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases
Status: RECRUITING
Conditions: Diabetes Mellitus|Hypertension|Cancer|Cardiovascular Diseases|Chronic Respiratory Disease|Kidney Disease, Chronic|Noncommunicable Diseases
Interventions: OTHER: COVID-19 outbreaks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 21 Day Irritancy Test of Azelaic Acid Pre-foam Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: azelaic acid pre-foam formulation|DRUG: Vehicle pre-foam formulation|DRUG: Water|DRUG: Sodium lauryl sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS
Status: WITHDRAWN
Conditions: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)|Respiratory Failure|Sars-CoV2
Interventions: DRUG: Rapamycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucagon Modulation of Ghrelin Secretion
Status: UNKNOWN
Conditions: Healthy Subjects|Obesity|Diabetes Mellitus, Type 1
Interventions: DRUG: Glucagon hydrochloride (GlucaGen®)|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Minocycline & Amoxicillin on Antibiotic Resistant Bacteria and Indigenous Microbiotas
Status: COMPLETED
Conditions: Antibiotic Resistant Bacteria
Interventions: DRUG: 3 doses of amoxicillin daily for 7 days|DRUG: 2 doses of minocycline daily for five days|OTHER: 2 doses of placebo daily for five days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion
Status: WITHDRAWN
Conditions: Degenerative Disc Disease|Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: PROCEDURE: PLF with autograft|BIOLOGICAL: PLF with NeoFuse|BIOLOGICAL: PLF with NeoFuse|BIOLOGICAL: PLF with NeoFuse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems
Status: COMPLETED
Conditions: Plaque|Gum Disease
Interventions: DRUG: 0.2% zinc lactate, 0.17% amine fluoride and 0.0275% sodium fluoride Mouthwash|DRUG: 0.057% sodium fluoride Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling
Status: UNKNOWN
Conditions: Pathological Gambling
Interventions: DEVICE: Real Deep TMS|DEVICE: Sham Deep TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, Five Parallel Groups Efficacy and Safety Study of NS 2330 (Tesofensine) (0.125 mg, 0.25 mg, 0.5 mg and 1.0 mg) Administered Orally Once Daily Over 14 Weeks in Levodopa Treated Parkinson Patients With Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: 1. Tesofensine (NS 2330)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics
Status: COMPLETED
Conditions: Tic Disorders|Tics|Tic, Motor|Tic Disorder, Childhood|Tourette Syndrome|Tourette Syndrome in Children|Tourette Syndrome in Adolescence
Interventions: BEHAVIORAL: Comprehensive Behavioral Intervention for Tics (CBIT)|DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Continuous Theta Burst Stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Parkinson's Disease: Probabilistic STN Targeting Under General Anaesthesia Without Micro-electrode Recordings vs Current Targeting Procedure
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: PROCEDURE: Surgery under general anesthesia with experimental targeting|PROCEDURE: Usual Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-BLR Versus C-BLR for CI-IXT in Children
Status: COMPLETED
Conditions: Convergence Insufficiency Intermittent Exotropia (CI-IXT)
Interventions: PROCEDURE: S-BLR|PROCEDURE: C-BLR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pre-medication With N-acetylcysteine and Simethicone to Improve Mucosal Visibility During Gastroduodenoscopy
Status: COMPLETED
Conditions: Mucosal Erosion
Interventions: DRUG: Simethicone 150mg|DRUG: N Acetyl cysteine 600mg|DRUG: Simethicone 150mg plus N Acetyl cysteine 600 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Rheumatoid Arthritis:Tolerance Induction by Mixed Chimerism
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Hematopoietic Stem Cell Transplantation|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Campath 1H|DRUG: GCSF|DRUG: Cyclosporins|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of STA-2 in Patients With Chronic Stable Angina
Status: COMPLETED
Conditions: Chronic Stable Angina
Interventions: DRUG: STA-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LYNX: A Novel Mobile App to Support Linkage to HIV/STI Testing PrEP for Young Men Who Have Sex With Men
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Diseases|Risk Reduction|Pre-Exposure Prophylaxis
Interventions: BEHAVIORAL: LYNX Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Crossmodal Learning in Therapeutic Processes (Task 2-2)
Status: TERMINATED
Conditions: Sensory Ataxia
Interventions: DEVICE: Vibro-tactile stimulation|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Favipiravir in Treatment of Mild & Moderate COVID-19 Infection in Nepal
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Favipiravir|DRUG: Placebo|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT