pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of Lp299v on Vascular Function in Patients With PASC
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: Lactobacillus Plantarum 299v Freeze Dried Capsule|OTHER: Freeze Dried Potato Starch Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Potentiation of Cetuximab by Tregs Depletion With CSA in Advanced Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Cyclophosphamide|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Prep Solutions to Reduce Bacteria Colony Counts in Patients Having a Vaginal Surgery
Status: SUSPENDED
Conditions: Surgical Site Infection|Vaginal Surgery
Interventions: OTHER: Baby shampoo|OTHER: Betadine|OTHER: Peridex|OTHER: TechniCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medico-economic Evaluation of the ONCORAL Program for Ambulatory Patients Under Oral Anticancer Drugs Versus Usual Care
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: ONCORAL therapeutic education|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation|Cardiac Rhythm Disorder|Left Atrial Dilatation|Cryptogenic Stroke
Interventions: DEVICE: Early implant of cardiac monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Interventions and Nutritional Supplementation for Patients With Long-lasting Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: BEHAVIORAL: Brief Intervention|BEHAVIORAL: Cognitive Behavioural Therapy|DIETARY_SUPPLEMENT: Seal oil|DIETARY_SUPPLEMENT: Soy oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Course of Interferon Treatment in Patients With HCV Infection
Status: COMPLETED
Conditions: Hepatitis C|Chronic Disease|Treatment
Interventions: DRUG: 16 weeks Interferon Tiw with Ribavirin|DRUG: 24 weeks Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for the Treatment of Freezing of Gait in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: DEVICE: rTMS|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)
Status: COMPLETED
Conditions: Sporadic Amyotrophic Lateral Sclerosis
Interventions: DRUG: Mexiletine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean Delivery
Status: NOT_YET_RECRUITING
Conditions: Hypotension During Surgery|Hypotension Drug-Induced
Interventions: DEVICE: Hypotension Prediction Index|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma
Status: COMPLETED
Conditions: Breast Neoplasms|Lymphoma|Neoplasm Metastasis|Testicular Neoplasms
Interventions: DRUG: interleukin-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Perioperative Ostomy Self-Management Telehealth for Cancer Patients and Family Caregivers
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: OTHER: Informational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analysis of the Kinematics of the Shoulder Complex in Sports "Overhead" Gestures Such as Kayaking Polo Throwing (Overhead)
Status: COMPLETED
Conditions: Kayak Polo|Overhead
Interventions: OTHER: Arm throws with his dominant arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy of Heating and Cooling Combination Therapeutic Device(OCH-S100)
Status: UNKNOWN
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Heating and cooling combination therapy|DEVICE: Sham heating and cooling therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Best Event Schizophrenia Trial--A Randomized Double-Blind Trial of Aripiprazole and Risperidone in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Prospective Multicenter Study Primary Onlay- Mesh After Elective Median Laparotomy in Patients With BMI ≥ 27
Status: TERMINATED
Conditions: Incisional Hernia|Obesity
Interventions: PROCEDURE: onlay mesh placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Oxytocin to Treat Vaginal Atrophy in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopause|Vaginal Atrophy
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Efficacy Of Atorvastatin For Lowering Cholesterol In High-Risk Patients With High Cholesterol
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Oral Eletriptan (40mg and 80mg), Oral Sumatriptan (25mg and 50mg) and Placebo
Status: COMPLETED
Conditions: Migraine With or Without Aura
Interventions: DRUG: Placebo|DRUG: Eletriptan 40 mg|DRUG: Eletriptan 80 mg|DRUG: Sumatriptan 25 mg|DRUG: Sumatriptan 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Maximal Incisal Opening Using Patient Specific Titanium Eminoplasty Versus Inlay Autogenous Bone Graft for Treatment of Chronic Mandibular Condylar Dislocation
Status: UNKNOWN
Conditions: Chronic Mandibular Condylar Dislocation
Interventions: DEVICE: Patient Specific Titanium Eminoplasty|PROCEDURE: Inlay Autogenous Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Among Healthy Children Receiving Fluzone® Quadrivalent, Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone® Quadrivalent Influenza Vaccine, No Preservative|BIOLOGICAL: Fluzone® Quadrivalent Influenza Vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow Reserve
Status: COMPLETED
Conditions: Hypercholesterolemia|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: LopiGLIK™ therapy|DIETARY_SUPPLEMENT: Armolipid Plus® therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study
Status: COMPLETED
Conditions: Breast Cancer|Hereditary Breast and Ovarian Cancer Syndrome
Interventions: DEVICE: TiLoop Bra|DEVICE: Protexa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Development and Evaluation of a Web-based Programme on Relapse Management for People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BEHAVIORAL: web-based intervention programme|BEHAVIORAL: web-based information material offered via the same platform (broca®) in addition to usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial of a E-intervention to Help Patients Newly Diagnosed With Cancer Cope Better: Pilot Study
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DEVICE: PTSD Coach|BEHAVIORAL: Game application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Diastolic Dysfunction|Cardiac MRI|Myocardial Perfusion
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Same-day 2 Sachets Picosulfate Versus High Volume PEG for Afternoon Colonoscopy
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: DRUG: High volume split-dose PEG|DRUG: 2 sachets of picosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adaptive Radiation Therapy for Head & Neck Cancer Patients
Status: COMPLETED
Conditions: Cancer of Head and Neck
Interventions: RADIATION: concurrent chemo + IGRT|RADIATION: neoadjuvant chemo + IGRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Luspatercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sinus Tarsi Versus Extensile Lateral Approach for Calcaneus Fractures
Status: UNKNOWN
Conditions: Intra-articular Fractures
Interventions: PROCEDURE: Sinus Tarsi approach|PROCEDURE: Extensile Lateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Transplant Bortezomib and High Dose Cyclophosphamide as Graft-Versus-Host Disease (GVHD) Prophylaxis
Status: COMPLETED
Conditions: Hematological Malignancy
Interventions: DRUG: Cohort 1-Bortezomib (Velcade ®)|DRUG: Cohort 2-Bortezomib (Velcade ®)|DRUG: Cohort 3-Bortezomib (Velcade ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Light Exposure on Pain in Hypermobile Ehlers-Danlos Syndrome
Status: RECRUITING
Conditions: Ehlers-Danlos Syndrome|Pain, Chronic
Interventions: DEVICE: White LED light|DEVICE: Green LED light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Kerecis Omega3 Wound Plus SOC vs. SOC Alone in Treating Severe Diabetic Foot Ulcers and Forefoot Amputations
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Dehiscence of Amputation Stump|Amputation
Interventions: DEVICE: Kerecis™ Omega3 Wound|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients With CSFP
Status: COMPLETED
Conditions: ST Segment Elevation Myocardial Infarction|Coronary Slow Flow Phenomenon
Interventions: DRUG: Alprostadil|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy
Status: TERMINATED
Conditions: Glioblastoma Multiforme (WHO Grade IV)|Anaplastic Astrocytoma (WHO Grade III)
Interventions: DRUG: 06Benzylguanine|GENETIC: MGMT P140K|DEVICE: Meltenyi CliniMacs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems
Status: RECRUITING
Conditions: PTSD|Physical Injury
Interventions: BEHAVIORAL: Stepped Collaborative Care|BEHAVIORAL: American College of Surgeons (ACS) Required Screening and Referral (Usual Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D3 Supplementation for Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Vitamin D Deficiency|Cardiomyopathy|Congestive Heart Failure
Interventions: DRUG: Placebo Comparator: Sugar Pill|DRUG: Vitamin D3 (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Function and Muscle Metabolism in Drepanocytose Affected Patient During a Moderate Intensity Exercise
Status: UNKNOWN
Conditions: Drepanocytose
Interventions: OTHER: Spectroscopy magnetic resonance of phosphorus 31
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addition of Hypofractionated High Dose Radiation in Oligometastatic Disease
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: Standard systemic therapy + radiotherapy|DRUG: Standard systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modifying Treatment Expectations in Depression: the Role of Social Learning
Status: COMPLETED
Conditions: Health Care Utilization
Interventions: BEHAVIORAL: Control video|BEHAVIORAL: Rationale video|BEHAVIORAL: Clinician testimonial|BEHAVIORAL: Patient testimonial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tadalafil and Sildenafil for Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Tadalafil|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Herceptin (Trastuzumab) in Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Taxane (docetaxel or paclitaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PK/PD Evaluation of Intravenous Administration of MRT5201 in Patients With OTC Deficiency
Status: WITHDRAWN
Conditions: Ornithine Transcarbamylase Deficiency
Interventions: BIOLOGICAL: MRT5201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Cost of a Simplified Post-Operative Radiograph (SPOR) Protocol
Status: UNKNOWN
Conditions: Fractures, Bone|Fracture Complications|Xray Complication
Interventions: DIAGNOSTIC_TEST: X-ray|DIAGNOSTIC_TEST: No-Xray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Personalized Self-care Support Program for Primary Care Patients With Diabetic Foot Ulcer
Status: NOT_YET_RECRUITING
Conditions: Foot Ulcer
Interventions: BEHAVIORAL: A personalised self-care support program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transversus Abdominis Muscular Training and Chronic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Lumbar stability exercises|OTHER: Protocolized Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Irritable Bowel Syndrome
Status: WITHDRAWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: co-biotic|DRUG: placebo 2T/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Performance of an Optimized 3D EPI SWI Sequence and a Non-EPI QSM SWI Sequence in Detecting the Central Vein Sign in Patients With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: cerebral MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First Human Dose Study Investigating Safety and Concentration of Study Medicine in the Blood Following Once Daily Oral Dosing of NNC0560-0004 in Healthy Adults.
Status: COMPLETED
Conditions: Healthy Volunteers - Liver Diseases
Interventions: DRUG: NNC0560-0004|DRUG: Placebo (NNC0560-0004)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESPRIT: European/Australasian Stroke Prevention in Reversible Ischaemia Trial
Status: COMPLETED
Conditions: Brain Ischemia|Transient Ischemic Attack|Arteriosclerosis
Interventions: DRUG: anticoagulation|DRUG: aspirin and dipyridamole|DRUG: aspirin alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism
Status: UNKNOWN
Conditions: Coronary Artery Stenosis|Maximal Platelet Aggregation|Late Platelet Aggregation|High Post-Treatment Platelet Reactivity
Interventions: DRUG: cilostazol|DRUG: clopidogrel|DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Docetaxel or Gemcitabine Hydrochloride in Treating Patients Urothelial Cancer
Status: COMPLETED
Conditions: Metastatic Urothelial Carcinoma of the Renal Pelvis and Ureter|Recurrent Bladder Carcinoma|Recurrent Urothelial Carcinoma of the Renal Pelvis and Ureter|Regional Urothelial Carcinoma of the Renal Pelvis and Ureter|Stage III Bladder Urothelial Carcinoma|Stage III Urethral Cancer|Stage IV Bladder Urothelial Carcinoma|Stage IV Urethral Cancer|Urethral Urothelial Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Docetaxel|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|Mixed Oligoastrocytoma
Interventions: DRUG: IL13-PE38QQR|PROCEDURE: targeted fusion protein therapy|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Stepped-care Model of Tailored Behavioural Medicine Pain Intervention in Primary Care
Status: TERMINATED
Conditions: Musculoskeletal Pain
Interventions: BEHAVIORAL: Hierarchical graded exposure|BEHAVIORAL: Graded activity|BEHAVIORAL: Physical exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Tegaserod Therapy in the Management of Dyspeptic Symptoms in Female Patients on Proton Pump Inhibitors for the Treatment of Heartburn.
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Tegaserod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Can Oral Vitamin B12 and Folate Supplementation Preserve Cognitive Function of Patients With Early Dementia?
Status: COMPLETED
Conditions: Dementia
Interventions: DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: folate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Active Warming Effects on Maternal and Neonatal Outcome During Cesarean Delivery
Status: UNKNOWN
Conditions: Hypothermia; Anesthesia
Interventions: DEVICE: forced air warming and warmed intravenous fluids|DEVICE: warmed intravenous fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Stapled Hemorrhoidopexy for the Treatment of Obstructive Defecation Syndrome
Status: COMPLETED
Conditions: Hemorrhoids|Defecation Disorder
Interventions: DIAGNOSTIC_TEST: Ballon expulsion test|DIAGNOSTIC_TEST: Colonic transit time|PROCEDURE: Stapled hemorrhodopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as an Adjunctive Treatment for Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Valbenazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Status: RECRUITING
Conditions: Prehabilitation|Malnutrition|Physical Functional Performance
Interventions: BEHAVIORAL: Nutrition|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of ARS-1 or Albuterol in Subjects With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ARS-1|DRUG: Albuterol MDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction
Status: COMPLETED
Conditions: Sleep Restriction|Impaired Glucose Metabolism
Interventions: DRUG: modafinil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Salvage Systemic Therapy With or Without Stereotactic Ablative Radiotherapy for Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Epithelial Ovarian Cancer
Interventions: OTHER: Standard salvage therapy|RADIATION: Standard salvage therapy + SABR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching to Reduced Oxidant or Nicotine Content Cigarettes in Smokers
Status: COMPLETED
Conditions: Tobacco Smoking Behavior
Interventions: OTHER: Reduced Nicotine Cigarettes|OTHER: Reduced ROS/RNS|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing
Status: COMPLETED
Conditions: Cancer|Cardiovascular Disease|Neurologic Dysfunction|Congenital Abnormalities|Hearing Loss
Interventions: BEHAVIORAL: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vorinostat and Bevacizumab in Treating Patients With Unresectable or Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: vorinostat|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects After CPAP Withdrawal for Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Cardiovascular Disease
Interventions: PROCEDURE: Withdrawal of continuous positive airway pressure treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Surufatinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusion of Autologous T Regulatory Cells (T Reg) at the Time of Transplantation of Allogenic Islets of Langerhans
Status: UNKNOWN
Conditions: Type1diabetes
Interventions: OTHER: Autologous T regulatory cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Gosogliptin|DRUG: Vildagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Manual Therapy on the Shoulder
Status: COMPLETED
Conditions: Range of Motion|Manual Therapies|Shoulder Joint Disorder
Interventions: OTHER: posterior glide mobilization|OTHER: Sleeper stretch|OTHER: thoracic manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sienna+® Injection Time Study 4 Arms
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DEVICE: Sienna+ retro|DEVICE: Sienna+ peri|DEVICE: Sienna+ retro 4-6|DEVICE: Sienna+ peri 4-6|DEVICE: Technetium 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biological Effects of Quercetin in COPD Phase II
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Emphysema|Chronic Bronchitis With Airway Obstruction
Interventions: DRUG: Quercetin 1000 mg|DRUG: Quercetin 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Repyflec Cognitive Remediation Group Training in Schizophrenia
Status: COMPLETED
Conditions: Indication for Modification of Patient Cognitive Status
Interventions: BEHAVIORAL: Repyflec cognitive remediation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder
Status: RECRUITING
Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: DRUG: Olanzapine Extended Release|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TaVNS Improves the Symptoms of Patients With Moderate to Severe CP/CPPS
Status: NOT_YET_RECRUITING
Conditions: Chronic Prostatitis
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation|DEVICE: Sham Transcutaneous Auricular Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Pentobarbital|DRUG: thiopental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
Status: RECRUITING
Conditions: Oropharyngeal Cancer|Neck Cancer|Human Papillomavirus|HPV|Anal Cancer|Cervical Cancer|Penile Cancer|Vulvar Cancer|Vaginal Cancer|Colon Cancer
Interventions: DRUG: Bintrafusp Alfa|DRUG: NHS-IL12|DRUG: Entinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Oral Vinorelbine in Patients With Metastatic Tumors
Status: COMPLETED
Conditions: Breast Cancer|Non Small Cell Lung Cancer|Prostate Cancer
Interventions: DRUG: vinorelbine oral formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Interrupted Sutures for Repair of Episiotomy or Second Degree Tears: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: repair of episiotomy or second degree tears|PROCEDURE: repair of episiotomy or second degree tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Versus Multiple Deployment of Metallic Stents for Inoperable Malignant Hilar Biliary Obstruction
Status: COMPLETED
Conditions: Klatskin Tumor
Interventions: DEVICE: Metallic stent deployment in hilar obstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Music and Stress Ball Application on Patients During Cataract Surgery
Status: NOT_YET_RECRUITING
Conditions: Cataract|Nursing Caries
Interventions: BEHAVIORAL: müzik müdahalesi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tipranavir/Ritonavir vs. Genotypically Defined Protease Inhibitor/Ritonavir in HIV Patients (RESIST-2)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tipranavir (with low dose ritonavir)|DRUG: Comparator protease inhibitor(CPI)/low dose ritonavir(r)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Association Between Cell-free Nucleic Acid in Blood, Urine and Microbiome in Stool With Pancreatobiliary Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Cholangiocarcinoma|Gallbladder Cancer
Interventions: DIAGNOSTIC_TEST: cell free DNA in blood and urine, metabolite/microbiome in urine and stool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Midazolam Versus Dexamethasone as an Adjuvant to Local Anesthetics in the Ultrasound Guided Hydrodissection of Median Nerve for Treatment of Carpal Tunnel Syndrome Patients
Status: COMPLETED
Conditions: Pain Syndrome
Interventions: DRUG: Dexamethasone|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Energy Restriction and Chewing on Neural Stem Cell Ageing and Adult Hippocampal Neurogenesis Associated Cognition
Status: COMPLETED
Conditions: Aging|Cognitive Decline
Interventions: BEHAVIORAL: Intermittent Energy Restriction|BEHAVIORAL: Chewing|BEHAVIORAL: Chewing + Intermittent Energy Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyperpolarized Imaging for New Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Initiation of CFTR Modulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Training and Enhanced Supported Employment in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Computer-Based Cognitive Enhancement Training Program|BEHAVIORAL: Work Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Cardiovascular Disease Detection With an Artificial Intelligence-enabled Stethoscope
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Heart Valve Diseases|Atrial Fibrillation|Heart Murmurs|Congestive Heart Failure|Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: AI-stethoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)
Status: RECRUITING
Conditions: Advanced Solid Tumor|DLBCL
Interventions: DRUG: RNK05047
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gleolan for Visualization of Newly Diagnosed or Recurrent Meningioma
Status: COMPLETED
Conditions: Meningioma
Interventions: DRUG: Gleolan (Aminolevulinic Acid Hydrochloride/ALA/ALA-HCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Study of Xolair in Chronic Obstructive Pulmonary Disease in Patients With Elevated IgE Levels
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Omalizumab (Xolair)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia
Status: COMPLETED
Conditions: NSCLC|Fatigue|Cachexia
Interventions: BIOLOGICAL: ALD518|BIOLOGICAL: ALD518|BIOLOGICAL: ALD518|BIOLOGICAL: Infusion of 0.9% Saline without ALD518
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer, MIRAGE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: CT-guided Stereotactic Body Radiation Therapy|RADIATION: MRI-guided Stereotactic Body Radiation Therapy|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors
Status: UNKNOWN
Conditions: Urethral Stricture, Male|Hormone Deficiency|Fibrosis
Interventions: PROCEDURE: Transurethral resection of the prostate or bladder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability of Protein and Amino Acids of Pea Protein Isolate in Healthy Volunteers
Status: COMPLETED
Conditions: Proteins
Interventions: DIETARY_SUPPLEMENT: Pea|DIETARY_SUPPLEMENT: Casein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Neuromuscular Training With K-tape in Footballer With Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprains|Proprioception|Pain|Balanced
Interventions: OTHER: Closed Kinetic Chain Exercise|OTHER: Neuromuscular Training with K Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Neuromuscular Fatigue Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: duloxetine|DRUG: Cyproheptadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PEG-Interferon Alfa-2b, Sargramostim, and Thalidomide in Treating Patients With Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: PEG-interferon alfa-2b|BIOLOGICAL: GM-CSF|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Atrial Fibrillation|Healthy Ageing|Hypercholesterolemia
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: ECG screening|DIAGNOSTIC_TEST: ECG Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Efficacy of Molnupiravir (EIDD-2801) to Eliminate Infectious Virus Detection in Persons With COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Infection, COVID-19
Interventions: DRUG: Molnupiravir 200 mg|DRUG: Molnupiravir 400 mg|DRUG: Molnupiravir 800 mg|DRUG: Placebo (PBO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Custirsen, paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Bladder Distension for Pain Relief in Nullliparous Patients Undergoing Diagnostic Office Hysteroscopy
Status: NOT_YET_RECRUITING
Conditions: Hysteroscopy
Interventions: OTHER: Empty bladder group|OTHER: Bladder distension group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Plus Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Salivary Gland Squamous Cell Carcinoma|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Salivary Gland Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Interventions: DRUG: erlotinib hydrochloride|DRUG: docetaxel|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Tissues From Egyptian Male Patients and Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Cancer.
Status: RECRUITING
Conditions: Microbiota in Patients With Urinary Bladder Carcinoma in Urine and Cancer Tissues
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia
Status: RECRUITING
Conditions: Gout|Hyperuricemia
Interventions: DRUG: dontinurad|DRUG: dotinurad + allopurinol|DRUG: allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Hydration Enabled by Human Recombinant Hyaluronidase (Hylenex)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: recombinant human hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and Circulating Tumor Cells in Breast Cancer
Status: COMPLETED
Conditions: Female Breast Carcinoma
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transvenous Approach for the Treatment of Cerebral Arteriovenous Malformations
Status: ACTIVE_NOT_RECRUITING
Conditions: Arteriovenous Malformations, Cerebral|Unruptured Brain Arteriovenous Malformation|Ruptured Brain Arteriovenous Malformation
Interventions: PROCEDURE: Standard Trans-Arterial Embolization (TAE)|PROCEDURE: Trans-Venous Embolization (TVE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Bacterial Conjunctivitis
Status: COMPLETED
Conditions: Acute Bacterial Conjunctivitis
Interventions: DRUG: IVIEW-1201|DRUG: Ofloxacin Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure
Status: UNKNOWN
Conditions: Antibiotics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Clindamycin 300 mg|DRUG: Amoxicillin with Clavulanic Acid 635mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Cervical Strain
Interventions: DRUG: Cyclobenzaprine|DRUG: Ibuprofen|DRUG: Ibuprofen plus Cyclobenzaprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for Erector Spinae Plane Catheter Insertion
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain, Acute|Shoulder Pain
Interventions: DIAGNOSTIC_TEST: Electrical stimulation|DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC