pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of iVR Treadmill on Gait in PD
Status: COMPLETED
Conditions: Parkinson Disease|Virtual Reality|Gait Disorders, Neurologic|Long Range Autocorrelations
Interventions: DEVICE: Virtual reality headset
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics and Pharmacodynamics of Vicagrel in Healthy Adult Subjects of Different CYP2C19
Status: COMPLETED
Conditions: Healthy Subjects|PK/PD
Interventions: DRUG: Vicagrel 6mg|DRUG: Clopidogrel 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Viramidine to Ribavirin in Patients With Chronic Hepatitis C Who Are Treatment-Naive
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Viramidine|DRUG: Ribavirin|DRUG: pegylated interferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Respiratory Auscultation Skills Among Medical Students: Digital Stethoscopes in Medical Education
Status: COMPLETED
Conditions: Auscultation|Breathing Sound|Asthma|Pneumonia|Pleural Effusion
Interventions: DEVICE: Digital stethoscope use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Zero Heat Flux Temp Monitor on Discharge Hypothermia Among Trauma Patients (RUZIT Trial)
Status: WITHDRAWN
Conditions: Hypothermia|Trauma|Temperature Change, Body
Interventions: DEVICE: Standard of Care Group|DEVICE: Active Warming Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Hydroxychloroquine and Ivermectin in COVID-19 Prophylaxis
Status: UNKNOWN
Conditions: Coronavirus Infections
Interventions: DRUG: Hydroxychloroquine|DRUG: Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dosage and Efficacy of Probucol-induced apoE to Negate Cognitive Deterioration
Status: COMPLETED
Conditions: Dementia of the Alzheimer Type|Age-related Cognitive Decline|Mild Cognitive Impairment Due to Alzheimer Disease
Interventions: DRUG: Probucol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Middle Term Effect of Red Yeast Rice on Plasma Lipids and Proteoma in Individuals With Suboptimal Cholesterolemia
Status: NOT_YET_RECRUITING
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Red yeast rice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection
Status: WITHDRAWN
Conditions: Coronavirus Infections|Pneumonia, Viral|Dyspnea
Interventions: DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (TAP) Block vs. Systemic Lidocaine: Effects on Recovery
Status: WITHDRAWN
Conditions: Pain|Surgery
Interventions: DRUG: Systemic lidocaine|DRUG: TAP BLOCK with ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Susceptibility Testing of Biofilm to Guide Treatment of Periprosthetic Joint Infections
Status: UNKNOWN
Conditions: Prosthetic Joint Infection|Prosthetic Infection|Hip Prosthesis Infection|Knee Prosthesis Infection
Interventions: DIAGNOSTIC_TEST: MIC or MBEC+MIC based treatment algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurophysiological Marker of ADHD in Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Psychiatric Diagnosis|Diagnosis, Psychiatric
Interventions: DIAGNOSTIC_TEST: electroencephalography absolute delta power|DIAGNOSTIC_TEST: electroencephalography relative delta power|DIAGNOSTIC_TEST: electroencephalography absolute theta power|DIAGNOSTIC_TEST: electroencephalography relative theta power|DIAGNOSTIC_TEST: electroencephalography absolute slow alpha power|DIAGNOSTIC_TEST: electroencephalography relative slow alpha power|DIAGNOSTIC_TEST: electroencephalography absolute fast alpha power|DIAGNOSTIC_TEST: electroencephalography relative fast alpha power|DIAGNOSTIC_TEST: electroencephalography absolute beta power|DIAGNOSTIC_TEST: electroencephalography relative beta power|DIAGNOSTIC_TEST: Korean ADHD rating scale|DIAGNOSTIC_TEST: Korean Version of Diagnostic Interview Schedule for Children Version IV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2
Status: COMPLETED
Conditions: Postacute Sequelae of Sars-CoV-2|Post-Acute COVID-19 Syndrome|Widespread Chronic Pain|Fatigue Syndrome, Chronic|Gait, Unsteady
Interventions: DEVICE: TENS - high-dose|DEVICE: TENS - low-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Tamibarotene|DRUG: Azacitidine|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-factorial Analysis of the Follicular Fluid Milieu to Explore the Discrepant Effect of Follicular Fluid Endometrial Flushing on Outcome of Assisted Reproduction Trial
Status: WITHDRAWN
Conditions: Infertility
Interventions: PROCEDURE: endometrial flushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Efficiency of Transcranial Direct Current Stimulation in the Treatment of Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: tDCS|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Bladder Urothelial Carcinoma|Advanced Renal Pelvis Urothelial Carcinoma|Advanced Ureter Urothelial Carcinoma|Advanced Urethral Urothelial Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Stage III Bladder Cancer AJCC v8|Stage III Renal Pelvis and Ureter Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Renal Pelvis and Ureter Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8
Interventions: DRUG: Avelumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Orthopedic Knee Measurement Using Lunar iDXA
Status: COMPLETED
Conditions: Hemi Knee Arthroplasty|Patello-femoral Osteoarthritis
Interventions: DEVICE: iDXA knee software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Interactions of ENG Subdermal Implants With Long-Acting Cabotegravir (CAB-LA) and LA Rilpivirine (RPV-LA) (CARLA)
Status: WITHDRAWN
Conditions: HIV-1-infection
Interventions: DRUG: Etonogestrel (ENG) Subdermal Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H5N1 Mix and Match With AS03
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: AS03 Adjuvant|OTHER: Phosphate Buffered Saline (PBS) diluent|BIOLOGICAL: Sanofi H5N1 Antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of Facial Cosmetic Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Cosmetic Techniques
Interventions: DRUG: Restylane-L®|DRUG: Restylane-L® Lyft|DRUG: Restylane Silk®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Piezotome-Corticision Assisted Orthodontics
Status: COMPLETED
Conditions: Mandibular Anterior Crowding|Piezocision|Pain Perception
Interventions: PROCEDURE: Piezotome-Corticision|DEVICE: Orthodontics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity and Type 2 Diabetes - Raising the Issue of Weight Management in Primary Care
Status: COMPLETED
Conditions: Weight Management|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Small Talk Big Difference Immediate access training|BEHAVIORAL: Small Talk Big Difference delayed access training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraosseous Infusion for Neonatal Asphyxiated Resuscitation
Status: COMPLETED
Conditions: Asphyxia Neonatorum
Interventions: PROCEDURE: Intraosseous infusion|PROCEDURE: Umbilical vein infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children
Status: RECRUITING
Conditions: Leukemia, Monocytic, Acute|Pediatric AML
Interventions: DRUG: Cladribine|DRUG: G-CSF|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Mitoxantrone|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Early NIPPV|DEVICE: Standard NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Healthy Volunteers to Assess Safety and Blood Levels of AZD5847 After Multiple Doses Over 14 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD5847|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait
Status: RECRUITING
Conditions: Gait Disorders, Neurologic|Parkinson Disease
Interventions: DEVICE: David Delight Plus Device|OTHER: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
Status: RECRUITING
Conditions: Obesity|Healthy Lifestyle
Interventions: OTHER: Lifestyle Intervention|DRUG: Dasatinib 100 MG|DRUG: Quercetin 1000mg|DRUG: Placebo|PROCEDURE: Abdominal adipose tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two Opposite Strategies of Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Weaning Failure
Interventions: OTHER: T Tube for 120 minuts|OTHER: Pressure Support Ventilation of 8 cmH2O for 30 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxford - Fibrates in Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Fenofibrate Capsules|DRUG: Placental Lactogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Boceprevir-based Therapy to Rescue HCV Genotype 1/HBV Infected Patients Refractory to Combination Therapy
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Stop trial intervention for boceprevir, PEG-IFN and RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Intervention modifiEs Outcome of Patients With implAntable Cardioverter dEfibrillator: The PEACE Study
Status: COMPLETED
Conditions: Implantable Defibrillator User
Interventions: OTHER: Individual interview with a qualified psychologist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With TNBC
Status: TERMINATED
Conditions: Triple Negative Breast Cancer|Inflammatory Breast Cancer Stage IV
Interventions: DRUG: Bemcentinib; pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rosuvastatin on Amnesia and Orientation Through Galveston Outcome Amnesia Test in Moderate Head Injury
Status: COMPLETED
Conditions: Head Injury
Interventions: DRUG: rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Metabolic Parameters of Antipsychotic Child Treatment With Ziprasidone, Aripiprazole, and Clozapine
Status: TERMINATED
Conditions: Weight Gain
Interventions: DRUG: metformin|BEHAVIORAL: healthy lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation
Status: RECRUITING
Conditions: Suicidal Ideation|Major Depressive Disorder
Interventions: DEVICE: MagVenture TMS Therapy System w/Theta Burst Stimulation|DEVICE: Sham MagVenture TMS Therapy System w/Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis
Status: UNKNOWN
Conditions: Infection, Fungal
Interventions: DRUG: Group 1 Natamycin 5% Suspension + voriconazole 1% eye drops; Group 2 Natamycin 5% Suspension + Vehicle eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quit Smoking: Optimizing Health Promotion Strategy
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: OTHER: Nicotine Replace Therapy (NRT) sampling|BEHAVIORAL: Simple exercise education (SEE)|OTHER: Chat-based instant messaging|OTHER: Chatbot for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CP-751,871 In Combination With Docetaxel In Advance Non-hematologic Malignancies
Status: COMPLETED
Conditions: Advanced Non-Hematologic Malignancies
Interventions: DRUG: CP-751,871|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helmet Ventilation in Acute Hypercapnic Respiratory Failure
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Helmet (Starmed)|DEVICE: Total Face mask (Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Achieving Very Low LDL-Cholesterol After Treatment With Statins on Steroidogenesis and Cognition
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease|LDL Cholesterol|Cognition
Interventions: DRUG: simvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Web-Assisted Peer Education for Early Diagnosis of Breast Cancer on Health Beliefs, Knowledge Levels and Breast Self-Examination in University Students
Status: RECRUITING
Conditions: University Students|Breast Self-examination|Health Education
Interventions: BEHAVIORAL: Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Collect Data on the Use of Eylea in Babies Born Too Early Who Have a Condition of the Eye Where Blood Vessels Grow Abnormally in the Retina (Retinopathy of Prematurity)
Status: RECRUITING
Conditions: Retinopathy of Prematurity|Newborns|Infants
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Empagliflozin in ESKD - A Feasibility Study
Status: RECRUITING
Conditions: Kidney Failure, Chronic|Heart Failure
Interventions: DRUG: Empagliflozin 25 mg thrice-weekly post-hemodialysis dosing|DRUG: Empagliflozin 10 mg daily dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Montelukast to Treat Bronchiolitis Obliterans
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Chronic Graft Versus Host Disease|Leukotriene|Montelukast|Stem Cell Transplant
Interventions: DRUG: Singulair (Montelukast Sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)
Status: UNKNOWN
Conditions: Dysphagia|Dysphonia|Subglottic Stenosis|Voice Disorders|Swallowing Disorder|Covid19|SARS (Severe Acute Respiratory Syndrome)|SARS Pneumonia|Quality of Life|SARS-CoV-2 Infection
Interventions: DIAGNOSTIC_TEST: Fibreoptic Endoscopic Evaluation of Swallowing (FEES)|DIAGNOSTIC_TEST: Videofluoroscopy|OTHER: Dysphagia Handicap Index (DHI)|OTHER: Voice Symptom Scale (VoiSS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Toripalimab Combined With Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma.
Status: SUSPENDED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Toripalimab injection (JS001)|DRUG: Paclitaxel, Albumin-Bound|RADIATION: Radiotherapy|DRUG: Platinum-Based Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Synbiotics on Morbidity and Mortality in Preterm Infants
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis|Sepsis
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium lactis|DIETARY_SUPPLEMENT: Bifidobacterium lactis plus İnülin|OTHER: Maltodextrin|DIETARY_SUPPLEMENT: İnulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Tranexamic acid|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Towards the Use of Instrumented Tests for Screening the Risk of Falling in Patients With Chronic Illness.
Status: COMPLETED
Conditions: Joint Osteoarthritis|Atherosclerosis of the Distal Arteries, Without Gangrene|Parkinson Disease|Chronic Obstructive Pulmonary Disease, Unspecified|Obesity, Unspecified
Interventions: DIAGNOSTIC_TEST: Exploratory physiopathology study, including non-invasive functional explorations carried out in patients with chronic pathology.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: THE EFFECTS OF DIRECT AND INDIRECT LARYNGOSCOPY ON CORMACK-LEHANE AND POGO SCORES
Status: COMPLETED
Conditions: Being a 5th Year Student at the Faculty of Medicine|No Previous Laryngoscopy Experience
Interventions: OTHER: Cormack-Lehane (C&L)|OTHER: POGO score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Two Different Methods During Intramuscular Antibiotic Injection: ShotBlocker, Local Vibration
Status: COMPLETED
Conditions: Injections|Pain|Satisfaction, Patient
Interventions: DEVICE: Effectiveness of ShotBlocker on the perceived pain and satisfaction during intramuscular antibiotic injection|DEVICE: Effectiveness of local vibrator device on the perceived pain and satisfaction during intramuscular antibiotic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Durvalumab, Tremelimumab and ,FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioactive Dietary Fibres and Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Alginate Bread|OTHER: Control Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer
Status: COMPLETED
Conditions: Adrenal Cortex Neoplasms
Interventions: DRUG: XR9576 (Tariquidar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Pharmaco-mechanical Thrombectomy in Management of Acute Lower Extremity Arterial Ischemia
Status: RECRUITING
Conditions: Acute Limb Ischemia
Interventions: DEVICE: pharmaco-mechanichal thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elagolix Versus Subcutaneous Depot Medroxyprogesterone Acetate for the Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Elagolix|DRUG: Subcutaneous depot medroxyprogesterone acetate (DMPA-SC)|DRUG: Placebo to Elagolix|DRUG: Placebo to DMPA-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Multispecies Probiotic on Migraine
Status: RECRUITING
Conditions: Migraine|Irritable Bowel Syndrome|Headache, Migraine
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum (CECT7484 and CECT7485)/ Pediococcus acidilactici (CECT7483)|OTHER: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Human Metabolic Profile and Gut Microbiota Under Various Dietary Quality
Status: COMPLETED
Conditions: Biomarkers
Interventions: OTHER: whole grain-wheat flour food+standardized meals|OTHER: refined wheat flour food+standardized meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient-centered and Efficacious Advance Care Planning in Cancer: the PEACe Comparative Effectiveness Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Advance Care Planning
Interventions: BEHAVIORAL: Facilitated advance care planning (in-person or telephonic)|BEHAVIORAL: Web-based advance care planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability Study Of PF-00868554 Administered As 3x250mg Oral Tablets (Wet Granulate, 3x250mg Oral Tablets (Dry Granulate) And 750mg Solution Under Fed State
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens Wearers
Status: RECRUITING
Conditions: Demodex Blepharitis
Interventions: DRUG: Lotilaner ophthalmic solution, 0.25%|DRUG: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Solid Tumor
Interventions: DRUG: AN2025|DRUG: AN0025|DRUG: Atezolizumab 1200 mg in 20 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Efficacy of RG2417 in Bipolar I Depression
Status: COMPLETED
Conditions: Bipolar I Depression
Interventions: DRUG: RG2417|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients
Status: COMPLETED
Conditions: Neurophysiology|Physiology
Interventions: OTHER: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Donepezil TDS|DRUG: Aricept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Metoclopramide Nasal Spray Solution in Diabetic Patients With Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis|Diabetic Gastroparesis|Diabetes|Diabetes Mellitus|Delayed Gastric Emptying
Interventions: DRUG: metoclopramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Defeating Urinary Incontinence With Exercise Training (DUET) Feasibility Study
Status: COMPLETED
Conditions: Toileting Disability|Functional Urinary Incontinence
Interventions: BEHAVIORAL: Defeating Urinary Incontinence with Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valuation in Depressed Mood, Anhedonia, and Anxiety
Status: RECRUITING
Conditions: Neurobehavioral Components of Reward and Loss Valuation
Interventions: BEHAVIORAL: cognitive behavioral therapy|BEHAVIORAL: valuation with instruction|BEHAVIORAL: valuation without instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immersive Virtual Reality in Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Mechanical Ventilation|Virtual Reality|Delirium
Interventions: DEVICE: Immersive Virtual Reality|DEVICE: EEG headband
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of Knee Flexor Muscles Strength in Patients With Patellar Instability
Status: COMPLETED
Conditions: Patella Dislocation Recurrent|Children, Only
Interventions: DIAGNOSTIC_TEST: Isokinetic measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optical System to Continuously Measure Arterial Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DEVICE: Experimental: OBPM 2015-MD-0022 - CHEST|DEVICE: Experimental: OBPM 2015-MD-0022 - CHEST & FINGER|DEVICE: Experimental: OBPM 2015-MD-0022 - FINGER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IMPAACT P1092: Steady State PK in Malnourished HIV Infected Children
Status: COMPLETED
Conditions: HIV Positive|Malnourished
Interventions: DRUG: ZDV+3TC+LPV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Once Per Day Regimen of Accelerated Partial Breast Irradiation for Improved Breast Appearance in Patients With Low Risk, Hormone Responsive Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Estrogen Receptor-Positive Breast Carcinoma|HER2-Negative Breast Carcinoma
Interventions: RADIATION: Accelerated Partial Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementation and Evaluation of the ChildTaks+ Intervention in the Czech Republic
Status: COMPLETED
Conditions: Mental Disorder|Mental Health Issue|Parent-Child Relations|Parent-child Problem|Child Mental Disorder|Eating Disorders|Eating Disorders in Adolescence
Interventions: BEHAVIORAL: ChildTaks+ intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Pharmacokinetics and Pharmacodynamics of SAR342434 to Insulin Lispro in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: SAR342434|DRUG: Insulin Lispro|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Hyper-sensitivity Assessment After Immediate Versus Delayed Dentine Sealing in Teeth for Indirect Tooth Colored Restorations
Status: UNKNOWN
Conditions: Hypersensitivity Dentin
Interventions: PROCEDURE: Immediate dentin sealing protocol|PROCEDURE: Delayed dentin sealing protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Cervical Stabilization and Oculomotor Exercises on Position Sense With Chronic Neck Pain
Status: UNKNOWN
Conditions: Chronic Neck Pain|Exercise Addiction
Interventions: OTHER: Classical Physiotherapy Program + Cervical Stabilization Exercises|OTHER: Classical Physiotherapy Program + Oculomotor Exercises|OTHER: Classical Physiotherapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Beyond Progression (BBP)
Status: COMPLETED
Conditions: Malignant Glioma|Grade 4 Malignant Glioma|Glioblastoma|Gliosarcoma
Interventions: RADIATION: Radiation Therapy|DRUG: Temozolomide|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy of an Online Social Network Intervention to Increase Social Support for Physical Activity
Status: COMPLETED
Conditions: Cardiovascular Disease|Cancer|Obesity
Interventions: BEHAVIORAL: online social network enrollment plus education and self monitoring|BEHAVIORAL: Web education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy
Status: NOT_YET_RECRUITING
Conditions: Blood Loss|Intensive Care|Anastomotic Leakage|Lymph Node Disease|Survival|Blood Transfusion
Interventions: PROCEDURE: LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (intervention)|DRUG: Enoxaparin 40 Mg/0.4 mL Injectable Solution|DRUG: Levofloxacin 500mg|PROCEDURE: LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (Conventional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).
Status: COMPLETED
Conditions: Cyclooxygenase Two Inhibitors|Etoricoxib|Periodontitis|Superoxide Dismutase|Saliva
Interventions: DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In Taiwan
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: valdecoxib|DRUG: naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes
Status: WITHDRAWN
Conditions: Diabete Type 2|Obesity
Interventions: DRUG: HU6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005)
Status: TERMINATED
Conditions: Hematopoietic Stem Cell Transplantation|Acute Graft Versus Host Disease|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Efprezimod alfa|DRUG: Placebo|DRUG: Methotrexate|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiorespiratory Diagnostic Study
Status: COMPLETED
Conditions: COPD|Asthma|Lung Cancer|Anemia|Congestive Cardiac Failure|Bronchiectasis|Interstitial Lung Disease|Long COVID|Upper Respiratory Disease|Healthy
Interventions: DEVICE: N-Tidal C handset
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hydrotherapy Versus Physiotherapy for Short-term Rehabilitation After Primary TKR
Status: COMPLETED
Conditions: Osteoarthritis|Total Knee Replacement
Interventions: OTHER: Hydrotherapy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial on Colorectal Cancer Screening Among Quality Circles of Primary Care Physicians
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Multilevel training intervention (intervention group)|OTHER: Multilevel training intervention (control group with crossover)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: Furmonertinib 160mg|DRUG: Furmonertinib 240mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Allergen Challenge Methodology: Assessment of a Vibrating Mesh Nebulizer for Allergen Administration
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Wright jet nebulizer|DEVICE: Aerogen Solo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Leukemia of Ambiguous Lineage|B Acute Lymphoblastic Leukemia|Mixed Phenotype Acute Leukemia
Interventions: DRUG: Azacitidine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Daunorubicin Hydrochloride|DRUG: Dexamethasone|DRUG: Hydrocortisone Sodium Succinate|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|OTHER: Pharmacological Study|DRUG: Prednisolone|DRUG: Thioguanine|DRUG: Vincristine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prewarming Effect in Preventing Perioperative Hypothermia
Status: UNKNOWN
Conditions: Hypothermia
Interventions: DEVICE: 3M™ Bair Hugger™ Preoperative & Outpatient Care Blanket|OTHER: Passive Prewarming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Body Radiation Therapy Followed by NALIRIFOX vs NALIRIFOX for Borderline Resectable Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Irinotecan liposome injection|DRUG: Oxaliplatin|DRUG: 5-Fluorouracil|DRUG: Leucovorin|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Anti-telomerase T CD4 Immune Responses for Predicting the Effectiveness of Immunotherapies Targeting PD1 / PDL1
Status: UNKNOWN
Conditions: Cancer
Interventions: OTHER: Biological samples|DRUG: Anti PD1/PDL1 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LAMS Choledochoduodenostomies: With or Without Coaxial Plastic Stent
Status: COMPLETED
Conditions: Biliary Obstruction|Pancreatic Cancer|Biliary Tract Neoplasms
Interventions: DEVICE: Double pigtail plastic stent through lumen-apposing metal stent|DEVICE: Lumen-apposing metal stent without double pigtail plastic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blueberry Study Aimed at Improving Cognition and Peripheral Blood Flow
Status: COMPLETED
Conditions: Vascular Stiffness|Cognitive Change|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Blueberries|DIETARY_SUPPLEMENT: Blueberry powder|DIETARY_SUPPLEMENT: Blueberry components capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hyaluronic Acid on Gingival Recession Treatment
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: BIOLOGICAL: HYALURONIC ACID|PROCEDURE: coronally advanved flap with connective tissue harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin to Prevent Wheezing Following Severe Respiratory Syncytial Virus (RSV) Bronchiolitis
Status: COMPLETED
Conditions: RSV Bronchiolitis
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069)
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: ER niacin/laropiprant|DRUG: Comparator : placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess SHR0302 Oral Solutions and Tablets in Healthy Subjects Clinical Studies of Relative Bioavailability
Status: COMPLETED
Conditions: Graft-versus-host Disease
Interventions: DRUG: SHR0302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transportation for Cancer Care Navigation Tool for Reducing Travel Barriers Among Patients With Solid Tumors Receiving Radiation Therapy
Status: NOT_YET_RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Discussion|OTHER: Educational Intervention|BEHAVIORAL: Health Promotion and Care|OTHER: Media Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Status: RECRUITING
Conditions: Solid Tumor|Advanced Solid Tumor|Metastatic Cancer
Interventions: DRUG: Alectinib|DRUG: Atezolizumab|DRUG: Erlotinib|DRUG: Trastuzumab + Pertuzumab|DRUG: Trastuzumab emtansine|DRUG: Vemurafenib|DRUG: Bevacizumab + Erlotinib|DRUG: Entrectinib|DRUG: Pralsetinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Trial Comparing Conventional Plaster and Thermoplastic Splints to Treat Pediatric Boxer's Fractures
Status: COMPLETED
Conditions: Bone Fractures|Splints|Metacarpal Fracture|Boxer's Fracture
Interventions: OTHER: Plaster Ulnar Gutter Splint|OTHER: Thermoplastic Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COES: Curing Order Effects on Sealants
Status: RECRUITING
Conditions: Dental Sealant|Sealant Retention
Interventions: DRUG: Ultradent Ultra Seal XT Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of BAY 77-1931 Orally Disintegrating Tablet
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Fosrenol ODT (Lanthanum Carbonate, BAY77-1931)|DRUG: Fosrenol chewable Tablet (Lanthanum Carbonate, BAY77-1931)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Networks and Renal Education: Promoting Transplantation
Status: COMPLETED
Conditions: End Stage Renal Disease|Living Donor Kidney Transplantation|Renal Dialysis
Interventions: BEHAVIORAL: COACH (Communicating about Choices in Transplantation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease
Status: NOT_YET_RECRUITING
Conditions: Cushing Disease
Interventions: DRUG: Fimepinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Liver Metastases
Interventions: DRUG: Floxuridine (FUDR)|DEVICE: Hepatic Artery Infusion Pump|DRUG: Heparinized Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Trimethoprim-sulfamethoxazole or Weekly Chloroquine Among Adults on ART in Malawi
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Standard of Care prophylaxis|DRUG: Chloroquine (CQ) prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION