pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Rhinosinusitis
Interventions: DRUG: Budesonide|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Craniotomy on Temporalis Function
Status: WITHDRAWN
Conditions: Pterional Craniotomy
Interventions: PROCEDURE: Traditional pterional craniotomy|PROCEDURE: Osteoplastic craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphologic Study of the Intersegmental Plane After Fully Thoracoscopic Segmentectomy
Status: UNKNOWN
Conditions: Video-assisted Thoracoscopic Surgery (VATS)|Segmentectomy
Interventions: OTHER: thoracic densitometry with contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients
Status: COMPLETED
Conditions: Preemptive Peripheral Nerve Block|Pain, Postoperative|Acute Pain
Interventions: DRUG: Ultrasound guided Rectus sheath block|DRUG: Intercostal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease
Status: RECRUITING
Conditions: Acute Graft-versus-host Disease|Acute GVHD|Chronic Graft-versus-host Disease|Chronic GVHD
Interventions: PROCEDURE: Skin punch biopsy|PROCEDURE: Peripheral blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery
Status: COMPLETED
Conditions: Epidural Analgesia|Mechanical Ventilation|Postoperative Complications|Analgesia
Interventions: PROCEDURE: thoracic epidural analgesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effect of Scaphoid, Hamate Mobilization and Neural Mobilization in Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Neural mobilization|OTHER: Scaphoid , hamate mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Trial of High Dose Vitamin C and Chemotherapy for Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine with escalating ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis
Status: RECRUITING
Conditions: Advanced Multiple Sclerosis|Progressive Multiple Sclerosis
Interventions: DRUG: Cladribine (MAVENCLAD®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sprayable PEG Barrier in Gynecologic Laparoscopy
Status: TERMINATED
Conditions: Postoperative Adhesion|Peritoneal Adhesion, Nos
Interventions: DEVICE: Spraygel|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Response of Subjects With Atopic Dermatitis or Psoriasis to Oral Vitamin D3
Status: COMPLETED
Conditions: Atopic Dermatitis|Psoriasis
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Release Technique on Mobility, Sensorimotor Function and Performance in Volleyball Players
Status: RECRUITING
Conditions: Athletes|Volleyball
Interventions: OTHER: Myofascial Release Techniques|OTHER: Sham myofascial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Prazosin Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Open Heart Surgery Patients With Forward Head Posture With and Without Perioperative Therapeutic Exercise
Status: COMPLETED
Conditions: Cardiac Rehabilitation
Interventions: OTHER: Group A: Patients with FHP receiving standard cardiac rehabilitation|OTHER: Group B: Patients with FHP receiving standard cardiac rehabilitation + therapeutic exercises|OTHER: Group C: Patients without FHP receiving standard cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome?
Status: COMPLETED
Conditions: Prader-Willi Syndrome|Growth Hormone Deficiency
Interventions: DRUG: Growth hormone (Genotonorm® or Omnitrope®)|PROCEDURE: DEXA, blood tests, H.G.P.O, osseous age.|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-Evaluation of Tumor Samples From Women With Breast Cancer With the in Vitro Diagnostic Kit "MammaTyperTM"
Status: COMPLETED
Conditions: Invasive Breast Cancer
Interventions: DEVICE: MammaTyper™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Hard Labial Reinforcement of a Mouthguard on the Degree of Satisfaction Among Rugby Players
Status: COMPLETED
Conditions: Satisfaction|Quality of Life
Interventions: DEVICE: XC mouthguard|DEVICE: XP mouthguard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Therapy in TRIPle Negative Breast Cancer With antiPDL1
Status: COMPLETED
Conditions: Invasive Ductal Breast Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Abraxane|DRUG: MPDL3280A|PROCEDURE: Surgery|DRUG: Anthra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
Status: COMPLETED
Conditions: Lipid Metabolism, Inborn Errors|Hyperlipidemias|Metabolic Diseases|Hypolipoproteinemia|Hypolipoproteinemias|Hypobetalipoproteinemias|Metabolism, Inborn Errors|Genetic Diseases, Inborn|Infant, Newborn, Diseases|Congenital Abnormalities|Metabolic Disorder|Hypercholesterolemia|Dyslipidemias|Lipid Metabolism Disorders
Interventions: DRUG: mipomersen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Endometrial Cancer|Kidney Cancer|Multiple Myeloma|Ovary Cancer|Prostate Cancer|Thyroid Cancer|Non-Hodgkin Lymphoma
Interventions: BEHAVIORAL: Adapting MultiPLe Behavior Interventions That eFfectively Improve (AMPLIFI) Cancer Survivor Health|OTHER: Diet-Exercise|OTHER: Exercise-Diet|OTHER: Combined Diet and Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Quadratus Lumborum Block on Perioperative Analgesia and Inflammatory Responses in Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bilateral QL block|DRUG: Non-QL block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eltrombopag for the Treatment of Immune ThrombocytoPenia (ITP) Secondary to Chronic Lymphoproliferative Disorders (LPDs)
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic|Autoimmune Thrombocytopenic Purpura|Autoimmune Thrombocytopenia|Chronic Lymphocytic Leukemia|Non Hodgkin's Lymphoma
Interventions: DRUG: Eltrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab 200 mg|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed|DIETARY_SUPPLEMENT: Folic acid 350-1000 μg|DIETARY_SUPPLEMENT: Vitamin B12 1000 μg|DRUG: Dexamethasone 4 mg|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EXOPULSE Mollii Suit, Motor Function & Multiple Sclerosis (EXOSEP 2)
Status: RECRUITING
Conditions: Sclerosis, Multiple|MS (Multiple Sclerosis)|Spasticity, Muscle|Spastic
Interventions: DEVICE: EXOPULSE Mollii Suit Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laboratory-Treated Lymphocyte Infusion After Haploidentical Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: peripheral blood lymphocyte therapy|DRUG: fludarabine phosphate|DRUG: methylprednisolone|DRUG: thiotepa|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophies|Muscular Dystrophy, Duchenne|Muscular Disorders, Atrophic|Muscular Diseases|Neuromuscular Diseases|Nervous System Diseases|Genetic Diseases, X-Linked|Genetic Diseases, Inborn
Interventions: BIOLOGICAL: CAP-1002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing The Impact Of Incorporating Charlson Comorbidity Scores On Patient Anxiety And Satisfaction
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Prostate Cancer Comorbidity Index (PCCI) score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Detection of Bloodstream Pathogens in Hematological Malignancies
Status: COMPLETED
Conditions: Bloodstream Infection
Interventions: DIAGNOSTIC_TEST: blood culture|OTHER: Anti fungal susceptibility testing or antibiotic susceptibility testing|OTHER: phenotypic identification methods of the isolated organism by Vitek2 (BioMerieux,France)|OTHER: Identification of the isolated organism by multiplex PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: high intensity interval training plus myotherapy|OTHER: home exercise plus myotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation
Status: TERMINATED
Conditions: Degenerative Mitral Valve Disease
Interventions: DEVICE: Transcatheter mitral valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia
Status: COMPLETED
Conditions: Obesity|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Naltrexone 25mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Same-Day HIV Testing and Treatment Initiation to Improve Retention in Care
Status: UNKNOWN
Conditions: HIV
Interventions: OTHER: Same-Day HIV testing and ART initiation|OTHER: Standard ART Initiation|OTHER: Sub-Study: Same-Day ART, CD4 Count >500|OTHER: Sub-Study: Standard Pre-ART Care, CD4 Count >500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: L-methylfolate|DRUG: OROS-Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
Status: COMPLETED
Conditions: Fibrin/Therapeutic Use|Blood Platelets|Molar, Third|Bone Regeneration
Interventions: PROCEDURE: Platelet-rich fibrin|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers
Status: COMPLETED
Conditions: MALARIA|FEVER|Sweating Fever|Chills|ANEMIA
Interventions: OTHER: 413ABM|OTHER: 414WRR|OTHER: 418JAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Linagliptin|OTHER: Placebo|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens
Status: COMPLETED
Conditions: Healthcare-associated Pneumonia (HCAP)|Hospital Acquired Pneumonia (HAP)|Ventilator Associated Pneumonia (VAP)
Interventions: DRUG: Cefiderocol|DRUG: Meropenem|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low-dose Interleukin-2 Treatment in Chronic Spontaneous Urticaria
Status: UNKNOWN
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Recombinant human interleukin-2 (rhIL-2)|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LS-SCLC
Status: UNKNOWN
Conditions: SCLC
Interventions: RADIATION: Conventionally fractionated concurrent chemo-radiotherapy|RADIATION: Accelerated hypofractionated concurrent chemo-radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;|At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;|534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;|The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
Interventions: DRUG: Diane-35;metformin;Clomiphene citrate; Human menopausal gonadotropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure
Status: COMPLETED
Conditions: Heart Failure|Cardiac Failure
Interventions: OTHER: Aerobic exercise more force
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IRIS PILOT - Extended Pilot Study With a Retinal Implant System
Status: UNKNOWN
Conditions: Retinitis Pigmentosa|Cone-Rod Dystrophy|Choroideremia
Interventions: DEVICE: Retinal Implant System (IRIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of IGIV-C in Patients With Myasthenia Gravis Exacerbations
Status: COMPLETED
Conditions: Myasthenia Gravis Exacerbations
Interventions: BIOLOGICAL: IGIV-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GLIMEPIRIDE + METFORMIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccination in Immunocompromized Patients
Status: COMPLETED
Conditions: Immunosuppression
Interventions: BIOLOGICAL: Virosomal influenza vaccine|BIOLOGICAL: Subunit influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury|Coronary Artery Bypass|Ischemic Preconditioning
Interventions: PROCEDURE: Remote Ischemic Preconditioning (RIPC)|PROCEDURE: sham-RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Atrial Fibrillation
Interventions: OTHER: Medical or interventional therapy for rhythm control in atrial fibrillation (antiarrhythmic drugs, ablation, electric cardio version)|OTHER: Usual care for atrial fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Electrical Stimulation on the Rate of Orthodontic Tooth Movement and the Dental Arches
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: DEVICE: electric current|DEVICE: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation
Status: RECRUITING
Conditions: Irrigation
Interventions: DRUG: Lactated Ringer's Irrigation|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: quaratusugene ozeplasmid|DRUG: pembrolizumab|DRUG: docetaxel|DRUG: ramucirumab|DRUG: Investigator's Treatment of Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Orally Administered BEBT-503 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: BEBT-503 20mg|DRUG: BEBT-503 40mg|DRUG: BEBT-503 80mg|DRUG: BEBT-503 120mg|DRUG: BEBT-503 180mg|DRUG: placebo 20mg|DRUG: placebo 40mg|DRUG: placebo 80mg|DRUG: placebo 120mg|DRUG: placebo 180mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE)
Status: TERMINATED
Conditions: Venous Thromboembolism|Lung Neoplasm
Interventions: DRUG: Tinzaparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma
Status: RECRUITING
Conditions: Peritoneal Malignant Mesothelioma
Interventions: BIOLOGICAL: Atezolizumab|BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Computed Tomography|PROCEDURE: Cytoreductive Surgery|DRUG: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Pemetrexed|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Ketogenic Diet on Lupus Nephritis Patients' Immunity
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Ketogenic Dieting
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DIETARY_SUPPLEMENT: Balanced diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Inhibition of Dipeptidyl Peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/CD13) in the Treatment of Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: IP10.C8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemigatinib in Treating Patients With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Including FGFR2 Rearrangement
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Baricitinib, a JAK Inhibitor, in the Treatment of Refractory Non-infectious Non-anterior Uveitis
Status: NOT_YET_RECRUITING
Conditions: Active Non-anterior Non-infectious Uveitis
Interventions: DRUG: Baricitinib 4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the STANDARD G6PD Rapid Test for Assaying the Enzymatic Activity of G6PD in French Guiana
Status: RECRUITING
Conditions: Paludism
Interventions: DIAGNOSTIC_TEST: blood samples (venous and capillary at the fingertip)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections
Status: NOT_YET_RECRUITING
Conditions: Full-thickness Rotator Cuff Tear|Rotator Cuff Tendinitis
Interventions: DRUG: Ketorolac|DRUG: Marcaine|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)
Status: COMPLETED
Conditions: Spinal Cord Injury (SCI)
Interventions: BEHAVIORAL: Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 3 Doses of Tiotropium Compared to Placebo in Adolescents (12 to 17 Yrs) With Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium bromide|DRUG: tiotropium bromide|DRUG: tiotropium bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰb Study of Remimazolam Tosylate in Healthy Volunteers
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Remimazolam Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema
Status: COMPLETED
Conditions: Nephrotic Syndrome|Edema
Interventions: DRUG: Acetazolamide and Hydrochlorothiazide Followed by Furosemide|DRUG: Furosemide and Hydrochlorothiazide Followed by Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Geriatric Assessment Adapted" Therapy for Ph- ALL Elderly Patients
Status: COMPLETED
Conditions: Leukemia, Lymphoblastic, Acute
Interventions: PROCEDURE: Geriatric assessment adapted therapy|PROCEDURE: Stem cells autotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ONM-100, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer
Status: COMPLETED
Conditions: Breast Cancer|Head and Neck Squamous Cell Carcinoma|Colorectal Cancer|Prostate Cancer|Ovarian Cancer|Urothelial Carcinoma|Non-small Cell Lung Cancer
Interventions: DRUG: ONM-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 3 Fixation Devices in Laparoscopic Ventral Herniotomy
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: laparoscopic ventral herniotomy|DEVICE: Protack|DEVICE: Securestrap|DEVICE: Glubran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Safety and Efficacy of Two Hyaluronic Acids for the Treatment of Knee Osteoarthritis Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: ARTZ|DEVICE: DUROLANE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma|Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasms|Hepatic Cancer|Hepatic Carcinoma
Interventions: DRUG: H3B-6527
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Influenza Vaccination in Seniors With TLR (Toll Like Receptor) Agonists
Status: COMPLETED
Conditions: Influenza Vaccination in Seniors
Interventions: DRUG: resiquimod|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Video-assisted Episiotomy Repair Training on Anxiety and Self-efficacy Levels in Midwifery Students
Status: NOT_YET_RECRUITING
Conditions: Episiotomy Wound
Interventions: OTHER: Video assisted episiotomy repair training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-Finding Safety Study of BIIB014 in Early-Stage Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIIB014|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Peripheral Arterial Tone to Detect Sleep-disordered Breathing in Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Sleep-Disordered Breathing
Interventions: DEVICE: WatchPAT 200 (TM)|OTHER: Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-resistant HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: AVX754|DRUG: 3TC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: FKB327|DRUG: Humira®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oxiris Membrane as a Treatment for Ischemia-reperfusion Syndrome in Cardiogenic Shock Treated With Extracorporeal Life Support (ECMO/ECLS): A Randomized Pilot Study ECMORIX
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: DEVICE: Oxiris membrane|DEVICE: Prismaflex membrane|BIOLOGICAL: Blood tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determinants of Pterygium Occurrence and Recurrence in a Rural African Population
Status: COMPLETED
Conditions: Pterygium
Interventions: PROCEDURE: Pterygium excision followed by grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pancreatic Islet Transplantation in the Anterior Chamber of the Human Eye - a Pilot Study
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Pancreatic islet transplantation in the anterior chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Dvectis Pads in Comparison to no Pad Use in Patients With Chronic Lumbar Spine Pain
Status: COMPLETED
Conditions: Back Pain|Back Disorder|Disease Lumbar Spine
Interventions: OTHER: Use of the Dvectis Single pad|OTHER: Use of the Dvectis Double pad|OTHER: Use of no pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Tolerability of REGN2222(SAR438584) in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN2222(SAR438584)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (RemeMG)
Status: RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: BIOLOGICAL: Telitacicept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma|B-Cell Prolymphocytic Leukemia|High Grade B-Cell Lymphoma, Not Otherwise Specified|Post-Transplant Lymphoproliferative Disorder|Recurrent Adult Burkitt Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Hairy Cell Leukemia|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes|DRUG: Bendamustine Hydrochloride|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sexual Health Counseling Based on the BETTER Model
Status: NOT_YET_RECRUITING
Conditions: Health Knowledge, Attitudes, Practice|Sexuality
Interventions: BEHAVIORAL: Behavioral: sexual health counseling based on the BETTER model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of NBI-98854 in Healthy Subjects
Status: COMPLETED
Conditions: Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects
Interventions: DRUG: NBI-98854 50 mg capsule once daily|DRUG: Ketoconazole 400 mg (200 mg twice daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treating Systemic Lupus Erythematosus (SLE) Patients With CTLA4-IgG4m (RG2077)
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Lupus Nephritis
Interventions: DRUG: CTLA4-IgG4m (RG2077)|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preserving Inferior Pulmonary Ligamen on Symptom Burden in Thoracoscopic Pneumonectomy
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Surgical Procedures|Patient Reported Outcome Measures
Interventions: PROCEDURE: Preserving IPL during surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Microcurrent in a Cardiovascular Rehabilitation Home-based Program
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: Exercise|DEVICE: Microcurrent|OTHER: Cardiovascular Risk Factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel + Prednisone With or Without Radiation for Castrate Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: PROSTATE CANCER
Interventions: DRUG: Docetaxel and Prednisone|DRUG: Docetaxel and Prednisone|DRUG: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics and Efficacy of MK-7288 in Adults With Sleep Apnea (MK-7288-010)
Status: COMPLETED
Conditions: Apnea, Sleep
Interventions: DRUG: MK-7288|DRUG: Placebo to MK-7288|DRUG: Modafinil|DRUG: Placebo to modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Partial Breast Irradiation With IMRT in Early Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms|Neoplasm Recurrence, Local
Interventions: RADIATION: Accelerated Partial Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pain and Kinematic Outcomes of Two Gait-Modifying Shoe Interventions
Status: WITHDRAWN
Conditions: Arthritis Knee
Interventions: DEVICE: Sole 1 - Neutral|DEVICE: Sole 1 - Offset|DEVICE: Sole 2 - Neutral|DEVICE: Sole 2 - Offset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Multiply-fortified Salt Among Women of Reproductive Age and Preschool Children in India
Status: COMPLETED
Conditions: Nutrient Deficiency
Interventions: DIETARY_SUPPLEMENT: Mutiply-fortified salt|DIETARY_SUPPLEMENT: Iodized salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacist Case Finding and Intervention for Vascular Prevention Trial
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Risk Factors|Blood Pressure|Cardiovascular Disease|Diabetes|Dyslipidemia
Interventions: OTHER: Pharmacist-led care pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Antibiotic Treatment Versus Duration Guided by Markers of Inflammation in the Treatment of AECOPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Levofloxacin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Postoperative Recurrence of Hepatocellular Carcinoma by Blocking RAK Cells With Anti-TIM-3
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Autologous RAK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Core Muscles Activation for the Increase of Quality in Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation
Interventions: OTHER: Core muscle activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin and Function in Older Adults
Status: COMPLETED
Conditions: Older Adults|Physical Function|Cognitive Function
Interventions: DRUG: Curcumin|DRUG: microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Subclinical Dose of Ketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy
Status: NOT_YET_RECRUITING
Conditions: Ectopic Pregnancy
Interventions: DRUG: esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases
Interventions: RADIATION: MR Guided Single Fraction Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).
Status: TERMINATED
Conditions: Hyperlipidemia|Dyslipidemia|Hypercholesterolemia
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differences in Eating Frequency Between Vegan and Omnivorous Diets
Status: COMPLETED
Conditions: Eating Behavior
Interventions: BEHAVIORAL: Vegan diet|BEHAVIORAL: Follow habitual, usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT)
Status: COMPLETED
Conditions: Hematologic Neoplasms|Graft-Versus-Host Disease
Interventions: DEVICE: Alpha-beta depleted T-cell infusion after post-transplant cyclophosphamide.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Layering Technique Selection for Ultimate Aesthetics in Anterior Composites
Status: UNKNOWN
Conditions: Poor Aesthetics of Existing Restoration
Interventions: PROCEDURE: Polychromatic layering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Paclitaxel Versus BIBF 1120 Priming Followed by BIBF 1120 Plus Paclitaxel in Early HER-2 Negative Breast Cancer With Proteomic and Dynamic Imaging Correlates
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: BIBF + Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Brain Circuit of Inhibitory Control in Obese Patients Undergoing Gastric Banding
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two-field Versus Three-field Lymph Node Dissection in ESCC After Neoadjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: PROCEDURE: Two-Field lymph node dissection|PROCEDURE: Three-Field lymph node dissection|PROCEDURE: Three-Field lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preimplantation Genetic Testing for Aneuploidies in Patients With Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Recurrent Implantation Failure
Interventions: PROCEDURE: PGT-A|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agatolimod Sodium, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent or Refractory Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Adult Non-Hodgkin Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Nodal Marginal Zone Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Agatolimod Sodium|RADIATION: Indium In-111 Ibritumomab Tiuxetan|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Radionuclide Imaging|BIOLOGICAL: Rituximab|PROCEDURE: Single Photon Emission Computed Tomography|RADIATION: Yttrium Y-90 Ibritumomab Tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation Versus Protective Stabilization for Pediatric Dental Treatment
Status: RECRUITING
Conditions: Child Behavior|Dental Caries in Children
Interventions: DRUG: Ketamine 50 MG/ML|DRUG: Midazolam Hcl 2Mg/Ml Syrup|PROCEDURE: Protective stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Etoricoxib in Healthy Adult Subjects Under Fasting Condition
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Etoricoxib 90 mg film coated tablet|DRUG: Arcoxia 90 mg film coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH