pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Inspiratory Muscle Strength Training and Incentive Spirometer on Postmenopausal Asthmatic Women
Status: COMPLETED
Conditions: Asthmatic|Postmenopausal Symptoms
Interventions: DEVICE: incentive spirometer|OTHER: Inspiratory muscle trainer device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing an Accelerated TMS Protocol for Methamphetamine Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Methamphetamine Use Disorder
Interventions: DEVICE: Sham TMS|DEVICE: Active TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability of BCX9930 in Participants With Either Complement 3 Glomerulopathy (C3G), Immunoglobulin A Nephropathy (IgAN), or Primary Membranous Nephropathy (PMN)
Status: TERMINATED
Conditions: Complement 3 Glomerulopathy|Immunoglobulin A Nephropathy|Membranous Nephropathy
Interventions: DRUG: BCX9930
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients
Status: TERMINATED
Conditions: Cancer|Pancreatic Cancer|Pancreatic Carcinoma
Interventions: DRUG: CPI-613|DRUG: CPI-613|DRUG: Gemcitabine|DRUG: Gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioelectrical Impedance Analysis of Not-celiac Wheat Sensitivity Patients
Status: COMPLETED
Conditions: Not-celiac Gluten (Wheat) Sensitivity
Interventions: DIETARY_SUPPLEMENT: wheat|DIETARY_SUPPLEMENT: xylose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: PADN|PROCEDURE: Sham operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome
Status: TERMINATED
Conditions: Schizophrenia and Disorders With Psychotic Features
Interventions: DRUG: Ziprasidone HCL (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Intracranial Atherosclerosis|Stenosis
Interventions: DRUG: Rivaroxaban|DRUG: Clopidogrel|DRUG: Aspirin|OTHER: Risk Factor Management in both arms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beta Blocker Interruption After Uncomplicated Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Beta-blockers withdrawal|DRUG: Continuation of the Betablockers (βB) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of L-citrulline and HIIT on Arterial Stiffness and MAFLD in Adolescents
Status: ENROLLING_BY_INVITATION
Conditions: Metabolic Dysfunction-Associated Fatty Liver Disease|Obesity, Adolescent|Arterial Stiffness
Interventions: DIETARY_SUPPLEMENT: L-citrulline|DIETARY_SUPPLEMENT: Carboxymethyl cellulose|OTHER: High Intensity Intervals Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OptimiZation Of Lipid Lowering Therapies Using a Decision Support System In Patients With Acute Coronary Syndrome.
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Ischemic Stroke
Interventions: DEVICE: Decision Support System (DSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive Azoospermia
Status: UNKNOWN
Conditions: Non-obstructive Azoospermia
Interventions: PROCEDURE: mTESE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess Efficacy in Subjects With Traumatic Spinal Cord Injury
Status: COMPLETED
Conditions: Erectile Dysfunction|Spinal Cord Injury
Interventions: DRUG: Vardenafil (Levitra, BAY 38-9456), 10 mg|DRUG: Placebo|DRUG: Vardenafil (Levitra, BAY 38-9456), 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Immunogenicity, Reactogenicity, Safety of a Booster of GSK Biologicals DTPw-HBV/Hib Kft Compared to DTPw-HBV/Hib
Status: COMPLETED
Conditions: Hepatitis B|Whole Cell Pertussis|Tetanus|Haemophilus Influenzae Type b|Diphtheria
Interventions: BIOLOGICAL: DTPw-HBV/Hib Kft vaccine GSK323527A|BIOLOGICAL: Tritanrix™-HepB/Hiberix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Probiotics Against Pathogenic Bacteria in Advanced ENT-Surgery
Status: COMPLETED
Conditions: Advanced ENT Surgery|Microbiological Flora in the Oropharynx and Lower Airways
Interventions: DIETARY_SUPPLEMENT: L. plantarum 299 and L. plantarum 299v (+maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pragmatic Randomized Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Effects of the COVID-19 Pandemic on the Hungarian Adult Population
Status: COMPLETED
Conditions: Questionnaire Designs|COVID-19 Pandemic|Psychological Stress|Coping Skills|Two-Item Generalised Anxiety Disorder Scale|Patient Health Questionnaire Anxiety and Depression Scale|Health Status Index|Subjective Health Complaint|Mood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: ALK+ Advanced NSCLC
Interventions: DRUG: Brigatinib|DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatoduodenectomy With or Without Ligamentum Teres Wrap Around Gastroduodenal Artery Stump for Prevention of Pancreatic Hemorrhage
Status: COMPLETED
Conditions: Pancreatoduodenectomy
Interventions: PROCEDURE: Ligamentum teres/falciform-plasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
Status: COMPLETED
Conditions: Anaesthesia|Toxicity
Interventions: DRUG: intravenous injection of test solution|DRUG: intravenous injection of test solution|DRUG: intravenous injection of test solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn More About the Safety and the Level of BAY 1747846 in Body Given as Injection Into the Vein at Increasing Single Doses in Japanese Healthy Male Participants
Status: COMPLETED
Conditions: Contrast Enhancement in Magnetic Resonance Imaging|Healthy Volunteers
Interventions: DRUG: BAY1747846|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Dose-Escalation Study of RO5083945 in Patients With Metastatic and/or Locally Advanced Malignant Epidermal Growth Factor Receptor (EGFR)+ Solid Tumors.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RO5083945
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Alpha-1 Modified Process (MP) In Subjects With Alpha-1-antitrypsin (AAT) Deficiency
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: alpha-1 proteinase inhibitor (human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Molidustat for Correction of Renal Anemia in Dialysis Subjects
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic
Interventions: DRUG: Molidustat (BAY85-3934)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Residents Learning Weight Management Counseling Skills
Status: RECRUITING
Conditions: Weight Management|Patient Counseling|Video Communication Asssessments
Interventions: BEHAVIORAL: Didatic Session 1: Core Foundation Course|BEHAVIORAL: The 3Ps Program|BEHAVIORAL: Didactic session 2|BEHAVIORAL: Email reinforcement|BEHAVIORAL: PowerPoint of the foundational course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Post Operative Pain|Appendicitis Acute|Surgery
Interventions: PROCEDURE: Transversus abdominis plane block|PROCEDURE: Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Cholecalciferol (Vitamin D3) for Delaying the Diagnosis of MS After a Clinically Isolated Syndrome
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Vitamin D|DRUG: Placebo|OTHER: Imaging|BIOLOGICAL: Lumbar puncture|BIOLOGICAL: Blood sampling|BIOLOGICAL: Urine samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Nutrition With Immune Enhancing Nutritional Supplement (Immunomodulation)
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: DIETARY_SUPPLEMENT: Nestle IMPACT Advanced Recovery|DIETARY_SUPPLEMENT: Nestle Boost High Protein Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sedation of Mechanically Ventilated Critically Ill Patients: Midazolam Versus Dexmedetomidine
Status: UNKNOWN
Conditions: Mechanically Ventilated Patients|Sedation|Dexmedetomidine|Midazolam
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Voreloxin and Cytarabine Combination in Acute Myeloid Leukemia in Humans
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Voreloxin injection and cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Reconstruction and Dental Rehabilitation of Maxillofacial Defects
Status: WITHDRAWN
Conditions: Maxillofacial Injuries
Interventions: DEVICE: NobelActive|DEVICE: KLS Martin Mandibular Reconstruction Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decoy Receptor 3 (DcR3) Polymorphisms in Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Systemic Lupus Erythematosus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: NNC0638-0355|DRUG: Placebo (NNC0638-0355)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children and Adolescents Aged From 7 to Less Than 18 Years Old With Autism Spectrum Disorder
Status: TERMINATED
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: Bumetanide Oral Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allicin Bioavailability From Garlic Supplements and Garlic Foods
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: crushed garlic clove|DIETARY_SUPPLEMENT: garlic powder tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).
Status: RECRUITING
Conditions: NF1|Cutaneous Neurofibroma|Monotherapy
Interventions: DRUG: Mirdametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Supervision Strategies to Improve Clinician Fidelity to Trauma-focused CBT
Status: UNKNOWN
Conditions: Post Traumatic Stress|Overall Functioning|Clinician Fidelity|Supervision
Interventions: BEHAVIORAL: Supervision Practices of TF-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sleep Quality in High School Students With Asthma - II
Status: COMPLETED
Conditions: Asthma|Sleep|Asthma in Children
Interventions: BEHAVIORAL: MAST - Managing Asthma & Sleep in Teens|BEHAVIORAL: ASMA - Asthma Self-Management for Adol|BEHAVIORAL: Information & Referral Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do You Arthroscopic Repair for Subscapularis Tendon Tear, Which Accounts for More Than Half of the 1st Facet? Or do You Perform Debridement?
Status: UNKNOWN
Conditions: Subscapularis Tendon Tear|Arthroscopic Repair|Arthroscopic Debridement
Interventions: PROCEDURE: arthroscopic repair|PROCEDURE: arthroscopic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Who Are Currently on Metformin Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 1.5 mg or 2.0 mg CJC-1134-PC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Carbamylated Erythropoietin to Treat Patients With the Neurodegenerative Disorder Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: Lu AA24493|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of G250 Peptide and IL-2 Following Surgical Resection of Locally Advanced/Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: G250 peptide|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Abobotulinum Toxin A on the Symptoms of Raynaud's Phenomenon
Status: TERMINATED
Conditions: Raynaud Phenomenon
Interventions: DRUG: AbobotulinumtoxinA|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Non-Clear Cell Renal Carcinoma (Ncc-RCC) Temsirolimus Versus Sunitinib
Status: COMPLETED
Conditions: Non-clear Cell Renal Cell Cancer
Interventions: DRUG: Temsirolimus|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Booster Vaccination in Different Doses of COVID-19 Vaccine (Vero Cell),Inactivated for Prevention of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: High-dosage of COVID-19 vaccine (Vero cell), Inactivated|BIOLOGICAL: Medium-dose COVID-19 Vaccine(Vero Cell),Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Surgical Conditions During Laparoscopic Herniotomy With Deep Neuromuscular Blockade
Status: COMPLETED
Conditions: Laparoscopic Herniotomy
Interventions: DRUG: Rocuronium and Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Automatic CPAP to Fixed CPAP for OSAS Following a Prediction Formula
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Comparison of automatic CPAP versus fixed CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma.
Status: COMPLETED
Conditions: Esophageal Cancer|Gastroesophageal Junction Cancer|Anastomotic Leak
Interventions: BIOLOGICAL: Porcine Fibrin Sealant (PFS)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol With Intrauterine Device Insertion
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Misoprostol|DIETARY_SUPPLEMENT: Magnesium Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Sofosbuvir + Velpatasvir With or Without Ribavirin in Treatment-Naive Adults With Chronic HCV Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: SOF|DRUG: VEL|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bispectral Index-Guided Versus Fixed Dose Administration of Desflurane During Balanced Anesthesia With Remifentanil
Status: COMPLETED
Conditions: Stabilizing Hypnotic Depth and Vital Sign During Balanced Anesthesia
Interventions: DRUG: Administering desflurane according to the patient's BIS value|DRUG: Administering desflurane at 1 MAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Recovery Guide Intervention for Recurrent Psychiatric Hospitalization
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Psychotic Depression
Interventions: BEHAVIORAL: Recovery Mentor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Different Chlorhexidine Concentrations
Status: UNKNOWN
Conditions: Dental Plaque|Gingivitis
Interventions: DRUG: Chlorhexidine 0.2% Mouthrinse|DRUG: Chlorhexidine 0.12% mouthrinse|DRUG: Chlorhexidine 0.06% mouthrinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oran Park Mask External Clinical Study (3) Marketing Claims Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Mask A (Oran Park Mask) then Mask B (Evora Mask)|DEVICE: Mask B (Evora Mask) then Mask A (Oran Park Mask)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Extensively Hydrolyzed Liquid Human Milk Fortifier on Growth and Tolerance in Moderately Premature Infants
Status: COMPLETED
Conditions: Complication of Prematurity
Interventions: DIETARY_SUPPLEMENT: Powder HMF|DIETARY_SUPPLEMENT: Liquid HMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage
Status: COMPLETED
Conditions: Miscarriage|Misoprostol
Interventions: DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Utilization of AMSC to Enhance Rotator Cuff Repair - Safety and Efficacy
Status: TERMINATED
Conditions: Rotator Cuff Tear
Interventions: DRUG: Suspension of human autologous MSC 3P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin
Status: TERMINATED
Conditions: Acute Chest Syndrome
Interventions: DRUG: Aspirin|DRUG: Atorvastatin|DRUG: Placebo Aspirin|DRUG: Placebo Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Detecting Traumatic Intracranial Hemorrhage With Microwaves and Biomarkers
Status: RECRUITING
Conditions: Brain Injuries, Traumatic|Biomarkers|Microwave Imaging
Interventions: DEVICE: Microwave scanning of the head
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sildenofil in Persistent Pulmonary Hypertension in Newborns
Status: UNKNOWN
Conditions: Persistent Fetal Circulation Syndrome
Interventions: DRUG: Sildenafil|DRUG: diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth
Status: RECRUITING
Conditions: Parenting|Parent-Child Relations|Child Behavior|Child Maltreatment
Interventions: BEHAVIORAL: Promoting First Relationships
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Preliminary Pharmacokinetics (PK) and Pharmacodynamics (PD) of Single and Repeat Oral Doses of GSK3008356 in Healthy and Obese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: GSK3008356|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ulinastatin on Bronchoalveolar Lavage Fluid of Inflammatory Factors in Patients With Ventilator-associated Pneumonia
Status: UNKNOWN
Conditions: Ventilator-associated Bacterial Pneumonia|Mechanical Ventilation Complication
Interventions: DRUG: Ulinaststin for injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Satavaptan Dose-Ranging Study in Normonatraemic Patients With Cirrhotic Ascites
Status: COMPLETED
Conditions: Ascites|Liver Cirrhosis
Interventions: DRUG: satavaptan (SR121463B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate the Safety and Efficacy of FOLFIRI / FOLFOX Plus Cetuximab as First-line Therapy in Patients With KRAS Wild-type Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Cetuximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Topical Gentamycin for Hereditary Hypotrichosis Simplex Caused by Nonsense Mutations in CDSN
Status: UNKNOWN
Conditions: Hereditary Hypotrichosis Simplex
Interventions: DRUG: Gentamicin Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of BioK+ 50B® on Glycemic Control in a Type 2 Diabetes Population
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: OTHER: BioK+ 100% probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S-1/Oxaliplatin for High Risk Patients Who Underwent Gastrectomy
Status: TERMINATED
Conditions: Stomach Cancer
Interventions: DRUG: S-1 (452500ACH)|DRUG: OXALIPLATIN (205803BIJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Lowering Effect of Supplementation With Korea Red Ginseng Associated With Reductions in Circulating Lp-PLA2 Activity and Lysophospatidylcholines and an Increase in Dihydrobiopterin in Prehypertensive Subjects
Status: COMPLETED
Conditions: Prehypertension
Interventions: DIETARY_SUPPLEMENT: KRG|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Assess The Reproducibility And Sensitivity Of Quantitative Sensory Testing In Patients With Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of SMS Nudging to Increase Coverage of Influenza Vaccination Among the Elderly
Status: NOT_YET_RECRUITING
Conditions: Influenza
Interventions: BEHAVIORAL: Norwegian SMS|BEHAVIORAL: Polish/Ukrainian SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis (SHaRCS)
Status: COMPLETED
Conditions: Recurrent Herpes Labialis
Interventions: DRUG: NB-001|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Salve for Skin Oxygenation and Blood Flow
Status: COMPLETED
Conditions: Skin Oxygenation|Peripheral Perfusion
Interventions: OTHER: Original Healing Salve (OHS)|OTHER: OHS base only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Prostate Cancer
Interventions: DRUG: everolimus|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of the Immune Modulator Dimethyl Fumarate With Alteplase in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Dimethyl Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiology of Cough Reflex Hypersensitivity
Status: COMPLETED
Conditions: Cough|Healthy Controls
Interventions: OTHER: Hydrochloric acid (0.15 molar)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study in Japanese Patients With Intermediate-2 or High Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis With Splenomegaly
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: SAR302503
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol's Role in Dementia Management
Status: NOT_YET_RECRUITING
Conditions: Dementia, Vascular|Dementia, Mixed
Interventions: DRUG: Cannabidiol Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Open Label Study to Assess PK and Safety of Plant Cannabis Extract
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: A1|DRUG: A2|DRUG: A3|DRUG: A4|DRUG: A5|DRUG: B1|DRUG: B2|DRUG: B3|DRUG: B4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Efficacy and Safety of HMI-115 in Male Subjects With Androgenetic Alopecia
Status: RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: placebo-Q2W|DRUG: HMI-115-120mg-Q4W|DRUG: HMI-115-240mg-Q4W|DRUG: HMI-115, 240mg-Q2W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Dose Response Using C2 CryoBalloon™ Swipe Ablation System for Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: DEVICE: C2 CRYOBALLOON SWIPE ABLATION SYSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histological, Genetic and Epigenetic Analysis of Procedures Related With Dental Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Peri-Implantitis|Peri-implant Mucositis|Implant Complication|Implant Tissue Failure
Interventions: PROCEDURE: Gingival and bone sample collection|PROCEDURE: Healthy individuals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Tolerability of Subcutaneous (SC) Trastuzumab Administration in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Early Breast Cancer (eBC) Using Either a Single-Use Injection Device or Manual Administration
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure, Reduced Ejection Fraction|Vitamin B12 Deficiency
Interventions: DIETARY_SUPPLEMENT: Chlorella pyrenoidosa|DEVICE: High Definition Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.
Status: COMPLETED
Conditions: Parkinson Disease|Multiple System Atrophy
Interventions: DRUG: Intranasal Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Remineralization of Early Enamel Caries in Permanent Teeth
Status: NOT_YET_RECRUITING
Conditions: White Spot Lesion
Interventions: DRUG: self assembling peptide p11-4 with fluoride|DRUG: 5% sodium fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pseudo Continent Perineal Colostomy vs Permanent Left Iliac Colostomy After Abdominoperineal Resection for Ultra Low Rectal Adenocarcinoma
Status: COMPLETED
Conditions: Rectal Neoplasms|Colostomy Stoma|Quality of Life
Interventions: PROCEDURE: Perineal pseudocontinent colostomy|PROCEDURE: Permanent left iliac colostomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketogenic Diet in MASLD-related cACLD
Status: NOT_YET_RECRUITING
Conditions: Steatohepatitis, Nonalcoholic|Steatosis of Liver|Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet|DIETARY_SUPPLEMENT: Very Low Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curative Resectability of Not Optimally Resectable Liver and/or Lung Metastases From Colorectal Carcinoma (CRC) Under Intensified Chemotherapy
Status: TERMINATED
Conditions: Colorectal Carcinoma
Interventions: DRUG: intensified chemotherapy (FOLFOXIRI/Bevacizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Intervention Empowerment Dementia
Status: UNKNOWN
Conditions: Empowerment|Self Efficacy|Quality of Life
Interventions: BEHAVIORAL: empowerment|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Four-Period, Four-Treatment, Four-Way Relative Bioavailability Study of CL-108 Under Fed and Fasted Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CL-108|DRUG: Vicoprofen|DRUG: Ultracet|DRUG: Phenergan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Ovarian Cancer|Sarcoma|Small Intestine Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab for Advanced Cancers in India
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC)|Non-Small-Cell Lung Carcinoma|Nonsmall Cell Lung Cancer|Kidney Cancer|Kidney Neoplasms|Renal Cancer|Renal Neoplasms
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Tolerance of a Zanubrutinib and BGB-11417 Combination in Patients Previously Treated for Waldenström Macroglobulinemia
Status: NOT_YET_RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: zanubrutinib + BGB-11417
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Supplementation After Surgical Treatment of Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Mineral Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Pulpotomy in the Management of Mature Permanent Tooth With Irreversible Pulpits
Status: RECRUITING
Conditions: Irreversible Pulpitis|Mature Teeth
Interventions: PROCEDURE: Pulpotomy|PROCEDURE: Root Canal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of the Fresh Extraction Socket in the Aesthetic Area
Status: RECRUITING
Conditions: Tooth Extraction Status Nos|Dental Implant|Bone Augmentation|Soft Tissue Augmentation
Interventions: PROCEDURE: Prosthetically driven implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of CArdiopulmonary Bypass Flow on Renal Blood Flow, Function and OXygenation
Status: COMPLETED
Conditions: Complication of Extracorporeal Circulation|Kidney Circulation Disorder|Renal Function Disorder
Interventions: PROCEDURE: Increased cardiopulmonary bypass flow|DRUG: Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) in Patients With Metastatic Castrate-resistant Prostate Cancer (CRPC) With Microtubule Directed Chemo or AR-directed Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Targeted Axillary Lymph Node Dissection in Node Positive Breast Cancer Patients Post Neo Adjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Node-positive Breast Cancer
Interventions: PROCEDURE: Targeted axillary lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Single Agent Axitinib as Maintenance Therapy for Patients With First Line Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Axitinib|DRUG: Bevacizumab|DRUG: 5-Fluorouracil|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chicory-derived Inulin on Abdominal Sensations and Bowel Motor Function
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Care for Polysubstance Use in Primary Care Settings (Co-Care)
Status: NOT_YET_RECRUITING
Conditions: Substance Use
Interventions: OTHER: Education and support for primary care providers (PCPS)|OTHER: Nurse Care Manager (NCM) visits|OTHER: Addiction specialist consultant|OTHER: Health coaching sessions|OTHER: Patient educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Two Marketed Investigational Products in Children With Diaper Rash
Status: COMPLETED
Conditions: Diaper Rash
Interventions: OTHER: Zinc Oxide Diaper Rash Ointment|OTHER: Aloe Vera/Tocopherol/Zinc Oxide Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of a Recombinant Adenovirus 5 Vectored COVID-19 Vaccine (Ad5-nCoV) With Two Doses in Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Ad5-nCoV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration (nAMD)
Interventions: BIOLOGICAL: Injection Brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Aerobic Exercise Capacity and Muscle Strenght in Individuals With COVID-19
Status: COMPLETED
Conditions: COVID-19 Pneumonia|COVID-19
Interventions: DEVICE: Kardiopulmonary exercise test (Quark KPET C12x/T12x device connected to the Omnia version 1.6.8 COSMED system)|DEVICE: Peripheral muscle strength measurement (microFET3 (Hoggan Health Industries, Fabrication Enterprises, lnc) and JAMAR hydraulic hand dynamometer (Sammons Preston, Rolyon, Bolingbrook).|DEVICE: Standard exercise tolerance test (a bicycle ergometer and recorded through the ergoline rehabilitation system 2 Version 1.08 SPI.)|DEVICE: Aerobic exercise training (a bicycle ergometer and recorded through the ergoline rehabilitation system 2 Version 1.08 SPI.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Sounds Measurement Using the Wearable Cardioverter Defibrillator (HS-WCD) Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: AUDICOR then LifeVest then AUDICOR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Statins on Cytokine Expression in Pneumonia
Status: WITHDRAWN
Conditions: Community Acquired Pneumonia|Cardiovascular Risk Factors
Interventions: DRUG: simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Tyroserleutide for Injection in Hepatocellular Carcinoma (HCC) Patients
Status: UNKNOWN
Conditions: Hepatocellular,Carcinoma
Interventions: DRUG: Tyroserleutide for injection ,chemotherapy(mitomycin, and Fluorouracil )|DRUG: the placebo ,chemotherapy(mitomycin, and Fluorouracil )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Onabotulinumtoxin A and Hyaluronic Acid Fillers in the Treatment of Facial Paralysis
Status: UNKNOWN
Conditions: Hemifacial Paralysis
Interventions: DEVICE: Juvederm|DRUG: Vistabex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use
Status: COMPLETED
Conditions: Opioid Use|Arthropathy of Knee|Pain, Postoperative
Interventions: DEVICE: RelieVRx headset|DRUG: multi-modality pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gingival Crevicular Fluid (GCF) Bactericidal Permeability Protein (BPI) and Interleukin (IL)-1 Beta
Status: COMPLETED
Conditions: Periodontitis|Gingival Crevicular Fluid|Interleukin 1-beta|Bactericidal Permeability Protein
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vortioxetine for MDD, Cognition, and Systemic Inflammatory Biomarkers
Status: WITHDRAWN
Conditions: Unipolar Major Depression|Stage I, II or III Breast Cancer
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lanthanum in Controlling Serum Phosphate Levels in Subjects With End Stage Renal Disease Who Require Treatment for High Levels of Phosphate in Their Blood
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Lanthanum carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Sutetinib Maleate Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GDC-0032|DRUG: GDC-0032
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE