pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of TAK-385 in the Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Placebo|DRUG: TAK-385|DRUG: TAK-385|DRUG: TAK-385|DRUG: Leuprorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrapartum Continuous Midwife Support on Maternal and Neonatal Stress Level
Status: UNKNOWN
Conditions: Labor Complication|Midwife|Stress|Labor Pain
Interventions: BEHAVIORAL: intrapartum uninterrupted midwife support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Participant Engagement and Retention Trial in a Public Hospital (PERTH): An RCT Protocol
Status: TERMINATED
Conditions: Intervention Study
Interventions: BEHAVIORAL: Interactive voice response system|BEHAVIORAL: Mother and baby affairs workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents
Status: RECRUITING
Conditions: Sciatica|Radiating Pain|Paresthesia|Dysesthesia
Interventions: PROCEDURE: Integrative Korean Medicine Treatment|PROCEDURE: lower limb motion style acupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hip and Knee Exercises on Knee Pain in Young Adult Females With Long-standing Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Hip specific resistance exercise|OTHER: Knee specific resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Intravenous Oxytocin Infusion Using Different Diluents on Neonatal Bilirubin & Sodium Levels
Status: UNKNOWN
Conditions: Neonatal Hyperbilirubinemia
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy
Status: ENROLLING_BY_INVITATION
Conditions: Neovascular Age-related Macular Degeneration|Wet Macular Degeneration
Interventions: GENETIC: RGX-314
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples
Status: COMPLETED
Conditions: Port-Wine Stain
Interventions: OTHER: Biopsy sample from Port Wine Stain Birthmark
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Residual Replication of HIV-1 in the Gut Associated Lymphoid Tissue (GALT) of Patients on Highly Active Antiretroviral Therapy (HAART): the ANRS EP 44 Study
Status: COMPLETED
Conditions: HIV Infection
Interventions: PROCEDURE: GI endoscopy and GALT biopsies|BIOLOGICAL: A sample of venous blood will also be collected
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardizing Care for Neuropsychiatric Symptoms and Quality of Life in Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease|Alzheimer Dementia (AD)|Aggression
Interventions: BEHAVIORAL: Non-Pharmacological Intervention|OTHER: Pharmacological Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: European eCLIPS™ Safety, Feasibility and Efficacy Study
Status: TERMINATED
Conditions: Saccular Aneurysm|Intracranial Aneurysm
Interventions: DEVICE: Implant eCLIPs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Acetylsalicylic Acid and Atorvastatin in Patients With Castrate-resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Acetylsalicylic acid|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Abiraterone (JNJ-589485) on the Pharmacokinetics of Pioglitazone Following Administration of Abiraterone Acetate (JNJ-212082) and Pioglitazone HCl Tablets in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Pioglitazone HCl|DRUG: Abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
Status: COMPLETED
Conditions: Cystocele|Uterine Prolapse|Urinary Incontinence
Interventions: DEVICE: grafted anterior prolapse repair|PROCEDURE: sutured anterior vaginal prolapse repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NP2 Enkephalin For Treatment of Intractable Cancer Pain
Status: COMPLETED
Conditions: Intractable Pain|Neoplasms
Interventions: BIOLOGICAL: NP2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern Zambia
Status: COMPLETED
Conditions: Malaria|Malaria, Falciparum
Interventions: DRUG: MDA with DHAp (Eurartesim)|DRUG: Focal MDA with DHAp (Eurartesim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Docetaxel, Cisplatin, and Capecitabine (DCX) in the Treatment of Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Smartphone-based App to Reduce Self-harm for CAMHS-treated Adolescents
Status: UNKNOWN
Conditions: Self-harm
Interventions: BEHAVIORAL: Volitional Help Sheet for self-harm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Teriparatide in the Treatment of Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: teriparatide|DRUG: teriparatide|DRUG: Placebo|DRUG: Calcium Supplement|DRUG: Vitamin D Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Preoperative/Postoperative Dexketoprofen Trometamol in Third Molar Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexketoprofen trometamol|DRUG: Preoperative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Psilocybin|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
Status: UNKNOWN
Conditions: Degenerative Disc Disease
Interventions: OTHER: Active Allograft|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket
Status: UNKNOWN
Conditions: Bone Loss
Interventions: DRUG: Lovastatin 40 MG|PROCEDURE: without drug with Bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BAriCitinib Healing Effect in earLy pOlymyalgia Rheumatica
Status: COMPLETED
Conditions: Polymyalgia Rheumatic (PMR)
Interventions: DRUG: Baricitinib|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of HepaStem in Patients With Acute on Chronic Liver Failure (ACLF)
Status: TERMINATED
Conditions: Acute on Chronic Liver Failure
Interventions: DRUG: HepaStem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Repeated Removal and Re-placement of Abutments Around Dental Implants
Status: UNKNOWN
Conditions: Peri-implant Mucositis
Interventions: DIAGNOSTIC_TEST: Repeated removal and re-placement of healing and prosthetic abutments
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Time Restricted Eating (TRE) and High-Intensity Interval Training (HIIT) to Improve Health in Patients With Metabolic Syndrome (METS)
Status: RECRUITING
Conditions: Metabolic Syndrome|Exercise|Weight Loss|Obesity|Cardiometabolic Syndrome|Time Restricted Eating
Interventions: BEHAVIORAL: High-Intensity Interval Training|BEHAVIORAL: Experimental: Time-Restricted Eating|BEHAVIORAL: High Intensity Interval Training & Time-Restricted Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of an Investigational Pneumococcal Vaccine in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Pneumococcal Infections|Pneumococcal Pneumonia
Interventions: BIOLOGICAL: Pneumococcal Vaccine|BIOLOGICAL: Pneumococcal Vaccine|BIOLOGICAL: Pneumococcal Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cariprazine for Comorbid Cocaine and Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid-use Disorder|Cocaine Use Disorder
Interventions: DRUG: Cariprazine 1.5 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma
Status: COMPLETED
Conditions: Breast Cancer|Skin Cancer
Interventions: DEVICE: CLIPT patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Duloxetine in the Treatment of Depression in Patients With Traumatic Brain Injury
Status: TERMINATED
Conditions: Traumatic Brain Injury|Depression
Interventions: DRUG: Duloxetine|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of CD4+ Memory Phenotype, Memory, and Effector T Cells in Vaccination and Infection
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Fluzone®|BIOLOGICAL: FluMist®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure
Status: RECRUITING
Conditions: Hypertension|Blood Pressure
Interventions: BEHAVIORAL: LowSalt4Life Application|BEHAVIORAL: Just-In-time Adaptive Intervention (JITAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Metronidazole as an Adjunct of Non- Surgical Treatment of Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DRUG: Placebo oral capsule|DRUG: Metronidazole 250 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Shoulder Pain Treatment: High Intensity Laser or Ultrasound
Status: COMPLETED
Conditions: Shoulder Pain Chronic
Interventions: DEVICE: Hıgh İntensity Laser (HILT)|DEVICE: Ultrasound|DEVICE: Hotpack|DEVICE: Transcutaneous electrical nerve stimulation|OTHER: Therapeutic exercises|OTHER: Balneotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants
Status: RECRUITING
Conditions: Premature
Interventions: DIETARY_SUPPLEMENT: Enfamil® DHA & ARA Supplement for Special Dietary Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare the Efficacy and Safety of BP102 vs. Avastin® in Combination With Paclitaxel/Carboplatin in First-line Treatment of Advanced or Relapsed NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer(NSCLC)
Interventions: DRUG: BP102, paclitaxel, carboplatin|DRUG: Avastin®, paclitaxel, carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 3 Lots of an Investigational Vaccine Against Respiratory Syncytial Virus (RSV) in Adults Aged 60 Years and Above
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effect of Dulaglutide on How Body Handles Digoxin in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Digoxin|BIOLOGICAL: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Prophylactic Effect of Rivaroxaban on Venous Thromboembolism in AECOPD
Status: UNKNOWN
Conditions: Acute Exacerbation Copd|Venous Thromboembolism
Interventions: DRUG: Rivaroxaban|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fluorescein-INtra-VItal Microscopy Versus Conventional Frozen Section Diagnosis for intraOperative Histopathological Evaluation
Status: COMPLETED
Conditions: Intracranial Tumor
Interventions: DRUG: Alcon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trauma Informed Childhood Obesity Care for Low-Income Minorities in Primary Care
Status: WITHDRAWN
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Families OverComing Under Stress Trauma Informed Care in Childhood Obesity among Minorities (FOCUS TIC-COM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: RADIATION: Standard of Care Adjuvant Breast Radiation|DRUG: Standard of Care HER2-targeted Therapy Without Adjuvant Breast Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Artery Blood Flow During Rest and One-leg Knee Extensor Exercise in Patients With COPD
Status: COMPLETED
Conditions: COPD|Healthy|Chronic Obstructive Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: One-legged knee-extensor exercise with Doppler measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter, Double-blind, Placebo Controlled Comparing Test Fluorouracil Cream to Carac Cream in Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Generic Fluorouracil Cream|DRUG: Carac® (Fluorouracil) Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Hydrogen Peroxide for Periodontal Therapy
Status: TERMINATED
Conditions: Periodontitis, Chronic
Interventions: DRUG: Hydrogen Peroxide Gel, 13 weeks|DRUG: Hydrogen Peroxide Gel, 26 weeks|OTHER: Scaling and Root planing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Healthy Eating Among Young Adult Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity|Neoplasms|Cancer
Interventions: BEHAVIORAL: Core|BEHAVIORAL: Simplified Nutrition Monitoring (Green)|BEHAVIORAL: Behavioral: Simplified Nutrition Monitoring (Red)|BEHAVIORAL: Nutrition Goals (Yes)|BEHAVIORAL: Nutrition Goals (No)|BEHAVIORAL: Supportive Text Messages (Yes)|BEHAVIORAL: Supportive Text Messages (No)|BEHAVIORAL: Lesson Delivery (Once)|BEHAVIORAL: Lesson Delivery (Weekly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAMCI: Advancing the Use of Computerized Screening in Healthcare
Status: COMPLETED
Conditions: Cognitive Dysfunction|Cognitive Impairment|Cognitive Decline|Cognitive Change
Interventions: DEVICE: CAMCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Evaluation in STEMI Patients Using FDY-5301
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myocardial Infarction|STEMI|Percutaneous Coronary Revascularization
Interventions: DRUG: FDY-5301|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TachoSil® Versus Standard Haemostatic Treatment of Haemorrhage in Cardiovascular Surgery (TC-023-IM)
Status: COMPLETED
Conditions: Haemorrhage|Haemostasis|Cardiovascular Surgery
Interventions: DRUG: fibrinogen (human) + thrombin (human)|DRUG: Standard haemostatic treatment in cardiovascular surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project IMPACT: Improving Memory Performance by Applying Cognitive Training
Status: COMPLETED
Conditions: Cocaine Use Disorders|HIV
Interventions: DEVICE: Active Cognitive Training (ACT)|DEVICE: Control Training (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Safety and PK/ PD Characteristics of ADC189 Between Hepatic Impairment and Normal Hepatic Function Subjects
Status: RECRUITING
Conditions: Influenza Type A|Influenza Type B
Interventions: DRUG: ADC189
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar Needlescopic Enucleation Versus Vapoenucleation of BPH
Status: COMPLETED
Conditions: Prostate Obstruction|Prostatic Hyperplasia|Prostatic Hypertrophy, Benign
Interventions: PROCEDURE: Bipolar Vapo-Enucleation of the prostate|PROCEDURE: Bipolar Needlescopic Enucleation of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe Congenital Hemostatic Defects, Cerebral MIcrobleeds and COGnition
Status: NOT_YET_RECRUITING
Conditions: Cerebral Microbleeds, Congenital Haemophilia, Congenital Von Willebrand Disease
Interventions: OTHER: 3-Tesla brain MRI and a comprehensive neuropsychological assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care Workers
Status: COMPLETED
Conditions: Respiratory Viral Infection|Common Cold|Severe Acute Respiratory Syndrome (SARS) Pneumonia|COVID-19|Corona Virus Disease
Interventions: DEVICE: nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of Child Drawing Hospital Scale (CD: H) and the Place of the Drawing in the Evaluation of Dental Anxiety
Status: COMPLETED
Conditions: Dental Anxiety|Dental Pain|Validation|Child Drawing Hospital Scale
Interventions: BEHAVIORAL: survey research
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in Adults
Status: TERMINATED
Conditions: Malaria|Plasmodium Vivax
Interventions: DRUG: Tafenoquine|DRUG: Chloroquine + Primaquine|DRUG: tafenoquine|DRUG: Chloroquine + Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using a Humanoid Robot to Distract Children With Chronic Conditions Undergoing Painful Procedures
Status: TERMINATED
Conditions: Chronic Diseases in Children
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Robot-assisted puncture procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Mesh Fixation Techniques in Elective Laparoscopic Repair of Incisional Hernia - ReliaTack™ v ProTack™
Status: COMPLETED
Conditions: Incisional Hernia|Hernia|Abdominal Hernia
Interventions: DEVICE: ReliaTack™|DEVICE: Protack™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DRUG: Diprospan|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Physiological Signals During and After COPD Exacerbations
Status: COMPLETED
Conditions: COPD|COPD Exacerbation
Interventions: DEVICE: Monitoring of cardiorespiratory parameters with BORA Band
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study on Postoperative Analgesia With Transversus Abdominis Plane Block to Local Anesthetic Infiltration With Ropivacaine in Laparoscopic Abdominal Surgery
Status: COMPLETED
Conditions: Analgesia|Ropivacaine|Laparoscopic Abdominal Surgery|Local Infiltration
Interventions: DRUG: Ropivacaine in Transversus abdominis plane|DRUG: Ropivacaine in Local infiltration at port site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Start of Oral Sildenafil 100mg for Erectile Dysfunction After Robotic Assisted Laparoscopic Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: sildenafil 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehospital Cervical Ripening Before Induction and the Maternal Experience
Status: TERMINATED
Conditions: Labor, Induced|Cervical Ripening
Interventions: DEVICE: Outpatient transcervical Foley balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate in Treating Patients With Previously Treated Metastatic Breast Cancer
Status: COMPLETED
Conditions: Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: DRUG: Eribulin Mesylate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Self-affirmation Versus Back Massage on Psychological Distress and Fear of Birth Among Primigravid Women in Third Trimester
Status: RECRUITING
Conditions: Self-affirmation, Back Massage
Interventions: BEHAVIORAL: Self-affirmation versus back massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of Astaxanthin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Astaxanthin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Periosteal Electrical Dry Needling in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: MOBILIZATION with MOVEMENT|OTHER: Periosteal electrical dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 4 Week, Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Mild to Moderate Alzheimer's Disease
Interventions: DRUG: AZD1446|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Milk Expression in Nulliparous Pregnant People
Status: COMPLETED
Conditions: Pregnancy Related|Breast Feeding|Milk Expression, Breast
Interventions: OTHER: Antenatal milk expression|OTHER: Education handouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Double Fortification (Iron and Zinc) in Synbiotic Milk to Under 5 Years Stunted Children Growth
Status: UNKNOWN
Conditions: Stunting
Interventions: DIETARY_SUPPLEMENT: fortified synbiotic milk|DIETARY_SUPPLEMENT: non-fortified synbiotic milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer-led Personalized Support Program
Status: RECRUITING
Conditions: Health-risk Behaviours|Drug Abuse
Interventions: OTHER: Health-risk behaviors|OTHER: Theory of planned behavior, Self-determination theory|OTHER: Assist them to adhere to their schedule of quitting drugs throughout the study period|OTHER: Assist them to adhere to their schedule of desirable health-related lifestyles/quitting drugs throughout the study period|OTHER: (AWARD) model|OTHER: Receive four independent 1-minute videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Lisdexamfetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infections
Status: RECRUITING
Conditions: Gram Positive Bacterial Infections
Interventions: DRUG: Oritavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy With Chronic Lung Diseases
Status: NOT_YET_RECRUITING
Conditions: Lung Disease Chronic|Lung Diseases, Interstitial|Lung Diseases, Obstructive
Interventions: OTHER: 6-minute walk distance (6MWD) test on ambient air|OTHER: 6-minute walk distance test with supplemental oxygen (approximately 3l/min, nasal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Xeloda (Capecitabine) and Docetaxel in Patients With Inflammatory or Locally Advanced Breast Cancer.
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Docetaxel|DRUG: Xeloda
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transverse Colostomy for Refractory Hemorrhagic Chronic Radiation Proctitis: a Prospective Cohort Study
Status: UNKNOWN
Conditions: Chronic Radiation Proctitis|Rectal Bleeding|Colostomy Stoma|Anemia
Interventions: PROCEDURE: Transverse colostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Front-of-pack Nutrition Label on the Nutritional Quality of Purchases in Campus Cafeterias
Status: COMPLETED
Conditions: Food Labelling
Interventions: BEHAVIORAL: Front-of-pack labelling 5-CNL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma|Bladder Cancer|Urinary Bladder Neoplasms
Interventions: DRUG: 75 approved agents|OTHER: COXEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increase Health Literacy Through Health Education to Improve Menstruation Related Self-care and Work Productivity
Status: RECRUITING
Conditions: Work-Related Condition|Menstrual Discomfort|Occupational Problems
Interventions: BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SUBLIVAC Phleum for Immunotherapy of Grass Pollen-Allergy
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: SUBLIVAC FIX Phleum Prat.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Influenza Virus Vaccine, AdimFlu-S (A/H1N1), in Pediatric Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A (H1N1) 2009 monovalent vaccine, inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Examine the Impact of a Therapy Dog Intervention on Loneliness and Related Health Outcomes in Vulnerable Populations
Status: COMPLETED
Conditions: Loneliness|Depression|Anxiety|Quality of Life
Interventions: BEHAVIORAL: Animal-assisted interaction|BEHAVIORAL: Conversational control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Is a Collective Person-centered Dialogue Intervention for Hospitalised COPD Patients Feasible?
Status: RECRUITING
Conditions: COPD Exacerbation Acute|Nutrition Poor|Physical Inactivity|Relatives
Interventions: OTHER: The collective person-centered dialogue intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: active rTMS + rehabilitation exercise|DEVICE: placebo rTMS+ rehabilitation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine or 5-Fluorouracil in Combination With Irinotecan and Cisplatin in Patients With Solid Tumor Malignancies
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Capecitabine|DRUG: 5-Fluorouracil (5-FU)|DRUG: Irinotecan|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MAP0010 in Asthmatic Children and Adolescents
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MAP0010 low dose|DRUG: MAP0010 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
Status: COMPLETED
Conditions: Unexplained Infertility|Polycystic Ovarian Syndrome|Anovulatory
Interventions: DRUG: Placebo|DRUG: Nimodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endothelial Injury and Development of Coronary Intimal Thickening After Heart Transplantation
Status: TERMINATED
Conditions: Cardiac Allograft Vasculopathy|Antibody Mediated Rejection
Interventions: DEVICE: Optical Coherence Tomography|DRUG: Acetylcholine|PROCEDURE: Brachial Artery Flow Mediated Dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Collection of Blood Samples in Patients With Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Stage III Non-Small Cell Lung Cancer AJCC v7|Stage IIIA Non-Small Cell Lung Cancer AJCC v7|Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy
Status: WITHDRAWN
Conditions: Sepsis and Coagulopathy
Interventions: DRUG: ART-123|DRUG: Placebo Comparator - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CYPHERTM Stent Post-Marketing Surveillance Registry (US-PMS)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: CYPHERTM Sirolimus-Eluting Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody
Status: RECRUITING
Conditions: Biliary Tract Cancer|Candonilimab|Claudin 18.2
Interventions: DRUG: cardonilizumab|DRUG: LM-302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Acetazolamide, Mannitol and N-acetylcysteine on Cisplatin-Induced Nephrotoxicity
Status: COMPLETED
Conditions: Cisplatin Nephrotoxicity
Interventions: DRUG: Acetazolamide|DRUG: Acetylcysteine|DRUG: Mannitol|DRUG: saline|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Functional Medicine On Wound Healing From Delayed Autologous Breast Reconstruction
Status: TERMINATED
Conditions: Breast Reconstruction
Interventions: PROCEDURE: Delayed autologous breast reconstruction|BEHAVIORAL: Perioperative Functional Medicine (FM) Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Status: RECRUITING
Conditions: Post-Traumatic Stress Disorders|Major Depressive Disorder
Interventions: DRUG: Ketamine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Pharmacokinetics of Simvastatin When Coadministered With PEX168 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PEX168|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage I or Stage II Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: vinblastine|PROCEDURE: fludeoxyglucose F 18 positron-emission tomography (PET) scan|PROCEDURE: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Sintilimab in Combination With IBI310 as Treatment in Patients With EBV-Positive Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions: DRUG: Sintilimab|DRUG: IBI310
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Esomeprazole (Nexium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of CNTX-6016 in Healthy Subjects
Status: COMPLETED
Conditions: Chronic Pain|Nociceptive Pain|Pain
Interventions: DRUG: CNTX-6016|OTHER: Other: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Exercise in Chronic Liver Disease Patients Undergoing Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Chronic Liver Disease and Cirrhosis|Frailty
Interventions: BEHAVIORAL: Supervised aerobic and resistance exercises|DIETARY_SUPPLEMENT: Dietary supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Study of Porfiromycin in Head and Neck Cancer and Other Cancer Patients With Solid Tumors
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Porfiromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3b Study of Vernakalant Injection in Patients With Recent Onset Symptomatic Atrial Fibrillation (AF)(MK-6621-045)
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Vernakalant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies
Status: COMPLETED
Conditions: Neonate|Pain|ELBW
Interventions: DRUG: 12% Sucrose|DRUG: 24% Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Low Level LASER Therapy in Treating Temporomandibular Muscle Disorders
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: RADIATION: Low Level LASER therapy|DEVICE: Hard occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
Status: COMPLETED
Conditions: Tooth, Impacted|Tooth Diseases|Stomatognathic Diseases
Interventions: DRUG: Ibuprofen 200Mg Oral Cap|DRUG: Ibuprofen 200Mg Oral Tablet|OTHER: Placebo Liquid Capsule|OTHER: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Evaluate Tolerability of PREZISTA or INTELENCE in HIV-1 Infected Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: darunavir (PREZISTA)|DRUG: etravirine (INTELENCE)|DRUG: ritonavir|DRUG: Other antiretroviral medications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BREAST ADM Trial for Alloplastic Breast Reconstruction
Status: RECRUITING
Conditions: Breast Reconstruction
Interventions: DEVICE: AlloDerm|DEVICE: AlloMax|DEVICE: DermACELL|DEVICE: Flex HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Lung Deposition With the Aeroneb Solo Adapter and a Standard Jet Nebulizer by SPECT-CT
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Technetium-99m - Diethylenetriaminepentaacetic acid|DEVICE: Aeroneb Solo Adapter|DEVICE: Opti-Mist Plus Nebulizer|OTHER: Planar scintigraphy|OTHER: Single photon emission computed tomography|OTHER: Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Late-evening Snacks on Patients With Primary Hepatocellular Carcinoma After Hepatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Neoplasms
Interventions: OTHER: late-evening snacks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Aspirin Vs Omega 3 Fatty Acid After Scaling and Root Planing in Type II Diabetic Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Type2 Diabetes
Interventions: OTHER: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Metformin|DRUG: Cisplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane Protective Effect on Ischemia-reperfusion Injury. Multicenter, Randomized Controlled Trial
Status: COMPLETED
Conditions: Microsurgical Free Flaps
Interventions: DRUG: Balanced anesthesia|DRUG: Total intravenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease.
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Omega-3 PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolomics and Microbiomics in Cardiovascular Diseases
Status: UNKNOWN
Conditions: Acute Heart Failure|NSTEMI - Non-ST Segment Elevation MI|STEMI - ST Elevation Myocardial Infarction|Myocardial Infarction, Acute|Sepsis|Cardiomyopathies|Dilated Cardiomyopathy|Ischemic Cardiomyopathy
Interventions: OTHER: Blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p