pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Neuromuscular Disease|Neurodegenerative Disease|Central Nervous System Disease
Interventions: GENETIC: HYNR-CS-Allo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Sensing of Beta-lactam Antibiotics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Phenoxymethyl Penicillin|DEVICE: Microneedle array
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: 68Ga-FAPI-04 and 18F-FDG PET/CT in Patients With Epithelial Ovarian Cancer: Compared With Histological Findings
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-04 PET/CT and 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of MK0524A on Cholesterol Levels (0524A-048)
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemia
Interventions: DRUG: laropiprant/niacin (MK0524A)|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anti-PD-1, Thymosin, and SOX in Neoadjuvant Treatment of cStage III Gastric/GEJ Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Esophagogastric Junction Adenocarcinoma
Interventions: DRUG: Anti-PD-1 Combined with Thymosin and SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of IoMT-based Exercise Program for the Elderly
Status: UNKNOWN
Conditions: Lower Back Pain|Knee Osteoarthritis
Interventions: OTHER: Home based exercise program via a smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Single-blind, Controlled Clinical Study of Cardiomyopeptidin on Improving Ischemia-reperfusion Injury in Patients With Acute ST-segment Elevation Myocardial Infarction After Primary PCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: cardiomyopeptidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback and Nomophobia in Young Adults
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Biofeedback
Interventions: OTHER: Neurofeedback|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension (OLE) Study of the Safety and Clinical Utility of IPX203 in Parkinson's Disease (PD) Participants With Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: IPX203
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Ketoconazole on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Hematologic Malignancy|Malignant Lymphoma
Interventions: DRUG: Romidepsin|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ConsideRAte Study - Splenic Stimulation for RA
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Active Stimulation|DEVICE: Sham Stimulation|DRUG: Baricitinib|DRUG: Background Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers
Status: COMPLETED
Conditions: Healthy Volunteers (Meningococcal Infection)
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A,C,Y and W) Tetanus Toxoid Conjugate vaccine MenACYW conjugate vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine|BIOLOGICAL: Meningococcal Polysaccharide (serogroups A,C,Y and W-135) Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Diphtheria and Tetanus Toxoids and Acellular Pertussis, inactivated Poliovirus and Haemophilus b Conjugate Vaccine|BIOLOGICAL: Diphtheria and Tetanus Toxoids and Acellular Pertussis, Hepatitis B and Inactivated Poliovirus Vaccine|BIOLOGICAL: Haemophilus b Conjugate Vaccine|BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine|BIOLOGICAL: Rotavirus Vaccine, Live, Oral, Pentavalent|BIOLOGICAL: Hepatitis B Vaccine|BIOLOGICAL: Measles, Mumps, and Rubella Virus Vaccine Live|BIOLOGICAL: Varicella Virus Vaccine Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Examining the Effect of Exogenous Ketone Supplementation on Glucose Control in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Exogenous Ketone Monoester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation
Status: UNKNOWN
Conditions: KRAS Gene|Colorectal Cancer|Liver Metastasis|Safe Margin|Radiofrequency Ablation
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Graft-versus-host-disease|Stem Cell Transplant Complications|Acute Myeloid Leukemia|Acute Lymphoid Leukemia
Interventions: DRUG: Ruxolitinib|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cabozantinib and Nivolumab for Carcinoid Tumors
Status: COMPLETED
Conditions: Carcinoid Tumor|Carcinoid Tumor of GI System|Neuroendocrine Tumors
Interventions: DRUG: Nivolumab|DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Consisting of Pegylated Liposomal Doxorubicin and Carboplatin in Malignant Gynecologic Tumours
Status: COMPLETED
Conditions: Cancer of the Ovary Treated as 2nd Line Therapy|Muellerian Mixed Tumours|Tumours of the Uterus|Cervical Cancers|Non-Epithelial Ovarian Tumours
Interventions: DRUG: Pegylated Liposomal Doxorubicin and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadriceps Strength Training on Gait Parameters and Energy Expenditure in Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Conventiional Physiotherapy|OTHER: Quadriceps Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: leucovorin calcium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder|Asthma|Executive Dysfunction|Emotional Problem|Behavioural Problem|Pre-Eclampsia|Death
Interventions: DIAGNOSTIC_TEST: SRS 2, CBCL, BRIEF-P
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Doses Escalation Study of SHR0302 in Rheumatoid Arthritis (RA) Patients
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SHR0302|DRUG: SHR0302 placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video-assisted Thoracoscopic Surgery - Exparel Study
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Moisturizing Creams on Skin Barrier Function
Status: COMPLETED
Conditions: Dry Skin|Skin Care
Interventions: DRUG: Developmental moisturizing cream 1|DRUG: Developmental moisturizing cream 2|OTHER: Standard cleanser soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients
Status: AVAILABLE
Conditions: Glioblastoma|Squamous Cell Carcinoma|Hodgkin Lymphoma|Non-hodgkin Lymphoma|Breast Cancer|Prostate Cancer|Gastric Cancer|Ovarian Cancer|Acute Leukemia|Pancreatic Cancer|Spindle Cell Sarcoma|Cancer|Tumor, Solid|Tumor, Brain|Esophageal Andeocarcinoma|Mixed Phenotype AML|Desmoplastic Round Cell Sarcoma
Interventions: DRUG: AVM0703|DRUG: Hydrocortisone|DRUG: Proton pump inhibitor
Study Type: EXPANDED_ACCESS
Clinical trial: Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Status: COMPLETED
Conditions: Maternal Death|Neonatal Death|Postpartum Haemorrhage|Pre-eclampsia|Eclampsia|Pregnancy Induced Hypertension|Puerperal Sepsis|Asphyxia|Neonatal Sepsis|Neonatal Jaundice
Interventions: OTHER: Maternal and neonatal emergency protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laparoscopic Transversus Abdominis Plane Block Versus Erector Spinae Plane Block in Bariatric Surgery
Status: RECRUITING
Conditions: Pain, Postoperative|Obesity|Analgesia
Interventions: PROCEDURE: Transversus abdominis block|PROCEDURE: Erector spinae block|PROCEDURE: Bariatric surgery|DEVICE: Endotracheal intubation|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fish Oil-derived Omega-3 Fatty Acids on Gut Microbiota and Lipid Metabolome in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Lipid Metabolism Disorder|Fatty Acid Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: omega-3 polyunsaturated fatty acids|DIETARY_SUPPLEMENT: corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Pembrolizumab, Carboplatin and Paclitaxel in Triple-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 89Zr-Anti-CLDN18.2 mAbs PET Imaging in Patients With CLDN18.2 Positive Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: DRUG: 89Zr-NY005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of Adhesion Barrier Mediclore Versus no Treatment in Patients With Total Thyroidectomy
Status: UNKNOWN
Conditions: Patients With Thyroidectomy (Scheduled)
Interventions: DEVICE: Mediclore® (adhesion barrier)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prospective Interventional Study on Reversibility of Type 2 Diabetes Mellitus With Hypocaloric Diet
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus in Obese
Interventions: OTHER: Low Calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias
Status: COMPLETED
Conditions: Anemia, Aplastic|Amegakaryocytic Thrombocytopenia|Diamond-Blackfan Anemia|Kostmann Syndrome
Interventions: DEVICE: Allogeneic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Status: COMPLETED
Conditions: Solitary Pulmonary Nodule|Lung Cancer
Interventions: PROCEDURE: Sequential pEBUS - ENB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Microneedle Lesion Preparation Prior to Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) for AK on Face
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: ALA|DRUG: Topical Solution Vehicle|DEVICE: IBL 10 mW|PROCEDURE: Microneedle lesion preparation|DEVICE: IBL 20 mW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guiding Pharmacopuncture Therapy for Supraspinatus Tendinopathy
Status: RECRUITING
Conditions: Pharmacological Action
Interventions: PROCEDURE: Pharmacoacupuncture with ultrasound guiding|PROCEDURE: Pharmacoacupuncture without ultrasound guiding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospitalization & Mortality in Patients With Iron Deficiency CKD and HF Treated With i.v. Iron.
Status: COMPLETED
Conditions: Iron Deficiency|Heart Failure|Chronic Kidney Disease
Interventions: DRUG: Iron Sucrose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy Online Plus (TOP+) - Comparing Two Online Interventions for Dealing With Challenging Life Circumstances
Status: UNKNOWN
Conditions: Mental Disorders|Online-Intervention
Interventions: BEHAVIORAL: Res-Up!|BEHAVIORAL: REMOTION|OTHER: Wait-Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Varicella Zoster Virus (VZV)-Reactivation in HIV-positive Individuals Enrolled in a Prospective Immunogenicity and Safety Trial of VZV Vaccine: PROVE-IT-Study
Status: WITHDRAWN
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Zostavax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA
Status: TERMINATED
Conditions: Stage IV Colorectal Cancer
Interventions: DRUG: Ascorbic Acid|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of LB80380 in the Treatment-naive Patients of Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: LB80380 90 mg|DRUG: LB80380 150 mg|DRUG: entecavir 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating IV Oncaspar® and IV Gemzar® in the Treatment of Solid Tumors and Lymphoma
Status: TERMINATED
Conditions: Tumors|Lymphoma
Interventions: DRUG: Oncaspar & Gemzar; advanced and/or solid tumors and lymphoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Biofeedback Intervention on Microbiome, Metabolome, and Clinical Outcomes in Pediatric IBD (Study 2)
Status: TERMINATED
Conditions: IBD
Interventions: BEHAVIORAL: Biofeedback|OTHER: Music Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of an Inexpensive Tablet-based Laparoscopic Box Trainer With a Standard Box Trainer
Status: COMPLETED
Conditions: Basic Laparoscopic Skills Training
Interventions: DEVICE: Training on low-cost box trainer|DEVICE: Training on standard box trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: HT-0712 vs. Placebo in Subjects With Age-Associated Memory Impairment (AAMI)
Status: COMPLETED
Conditions: Age-Associated Memory Impairment (AAMI)
Interventions: DRUG: HT-0712|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zainidip in Renal Artery Stenosis
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: stent|DRUG: Aspirine|DRUG: Clopidogrel|DRUG: Lercanidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P2Et Extract in the Symptomatic Treatment of Subjects With COVID-19
Status: UNKNOWN
Conditions: COVID|Coronavirus Infection|SARS-CoV 2|COVID19
Interventions: DRUG: P2Et (Caesalpinia spinosa extract)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab (MEDI4736) in Frail and Elder Patients With Metastatic NSCLC (DURATION)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Metastatic Lung Cancer|Non Small Cell Lung Cancer|Lung Adenocarcinoma Metastatic|Large Cell Lung Carcinoma Metastatic
Interventions: DRUG: Durvalumab|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: nab-Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Interleukin-13 Pathways on Pain and Itch Sensitivity
Status: NOT_YET_RECRUITING
Conditions: Itch
Interventions: OTHER: Histamine|OTHER: Cowhage|OTHER: bovine adrenal medulla (BAM8-22)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ex Vivo Lung Perfusion (EVLP) in Reconditioning Marginal Donor Lungs for Transplantation
Status: RECRUITING
Conditions: Lung Transplant
Interventions: PROCEDURE: EVLP Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Acute Graft Versus Host Disease
Interventions: DRUG: Tacrolimus (TAC)|DRUG: Methotrexate (MTX)|DRUG: Rapamycin (RAPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Participants With Early Stage Relapsing Remitting Multiple Sclerosis (RRMS)
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Trial of Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Creatine monohydrate or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Lucentis Combined With Proton Beam Irradiation in Treating Wet Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Proton beam irradiation and ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: PROCEDURE: Global/single cell gene expression profiles obtained from Synovial biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children
Status: UNKNOWN
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: Japanese encephalitis chimeric vaccine (JECV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Targeted Intramyocardial Delivery of Auto CD34+ Stem Cells for Improving Exercise Capacity in Subjects With Refractory Angina
Status: COMPLETED
Conditions: Chronic Myocardial Ischemia|Refractory Angina Pectoris|Advanced Coronary Heart Disease
Interventions: BIOLOGICAL: Auto-CD34+ cells|BIOLOGICAL: Placebo: Diluent used to suspend Auto-CD34+ cells|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Collaborative Intervention for Improving Cancer Pain Management in Rural and Hispanic Cancer Survivors (ASCENT)
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm|Hematopoietic and Lymphatic System Neoplasm
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Questionnaire Administration|OTHER: Electronic Health Record Review|PROCEDURE: Health Telemonitoring|BEHAVIORAL: Cancer Pain Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing An Oral Janus Kinase Inhibitor, AZD4205 as Monotherapy in Patients Who Have PTCL (JACKPOT8)
Status: COMPLETED
Conditions: Relapsed or Refractory Peripheral T Cell Lymphoma
Interventions: DRUG: AZD4205
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IR-guided Ablation (IRGA) Combined With Stereotactic Ablative Radiation (SABR) for Large Lung Tumors
Status: TERMINATED
Conditions: Recurrent Non-small Cell Lung Cancer
Interventions: RADIATION: Stereotactic body RT and IRGA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)|Multiple Sclerosis (MS) Relapsing Remitting|Multiple Sclerosis (MS) Primary Progressive|Multiple Sclerosis (MS) Secondary Progressive|Radiologically Isolated Syndrome|Clinically Isolated Syndrome|Healthy
Interventions: OTHER: Video-oculography / Social cognition tasks / Neuropsychological evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Selinexor, Ruxolitinib and Methylprednisolone
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: DRUG: Selinexor|DRUG: Ruxolitinib|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)
Interventions: DRUG: Metformin Versus a combination of Metformin and Thymoquinone (TQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Rising Dose Study of MK-8150 (MK-8150-001)
Status: COMPLETED
Conditions: Hypertension|Isolated Systolic Hypertension (ISH)
Interventions: DRUG: MK-8150 2.0 mg|DRUG: MK-8150 10 mg|DRUG: MK-8150 40 mg|DRUG: MK-8150 90 mg|DRUG: MK-8150 5.0 mg|DRUG: MK-8150 20 mg|DRUG: MK-8150 60 mg|DRUG: MK-8150 120 mg|DRUG: MK-8150 160 mg|DRUG: MK-8150 320 mg|DRUG: MK-8150 600 mg|DRUG: MK-8150 900 mg|DRUG: MK-8150 1200 mg|DRUG: Placebo for MK-8150|DRUG: MK-8150 50 mg|DRUG: MK-8150 100 mg|DRUG: MK-8150 200 mg|DRUG: MK-8150 400 mg|DRUG: MK-8150 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease
Status: COMPLETED
Conditions: Anal Fistula
Interventions: DRUG: ASCs (Cx401, company code)|DRUG: Fibrin adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese Men
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: NNC0480 0389|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Coarsucam® (artésunate (AS) + amodiaquine (AQ) as fixed dose combination)|DRUG: Coartem® (arthemether+ lumefantrine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 1-year Study in Adolescents to Assess the Long-term Safety of Almotriptan Malate When Treating Their Migraine Headaches
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Almotriptan Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Efficacy of Smoking Quit Line in the Military (AFIII Renewal)
Status: COMPLETED
Conditions: Initial Efficacy of Quit Line|Efficacy of Secondary Reengagement Intervention
Interventions: BEHAVIORAL: Rate reduction intervention|BEHAVIORAL: Recycling Group|BEHAVIORAL: Choice Group|BEHAVIORAL: Proactive QL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Myocardial Necrosis and Depression: Antiplatelet Effect of Reuptake Inhibition of Serotonin
Status: TERMINATED
Conditions: Depression|Coronary Artery Disease
Interventions: DRUG: Sertraline|DRUG: No treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Rasagiline on Sleep Disturbances in Parkinson's Disease
Status: COMPLETED
Conditions: Sleep Disturbances|Parkinsons's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic and Sedative Effects of Esmketamine and Remifentanil Combined With Propofol Respectively in Septic Shock Patients With Invasive Mechanical Ventilation
Status: NOT_YET_RECRUITING
Conditions: Patients With Septic Shock Admitted to the ICU on Invasive Mechanical Ventilation
Interventions: DRUG: Esketamine|DRUG: Remifentanil|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Results of Education and Counseling for Persons Undergoing Genetic Testing for Hereditary Nonpolyposis Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: loss of heterozygosity analysis|OTHER: microsatellite instability analysis|OTHER: mutation analysis|OTHER: counseling intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate the Effect of Erenumab on Blood Pressure When Given Concomitantly With Subcutaneous Sumatriptan
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Placebo|DRUG: Sumatriptan|DRUG: Erenumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases
Status: RECRUITING
Conditions: Metastases
Interventions: DRUG: Yttrium-90 (Y-90) resin microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-inferiority, Comparative Study Between Foraseq®, Eurofarma´s Formoterol/Budesonide and Alenia® in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Formoterol/Budesonide|DRUG: Foraseq|DRUG: Alenia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Association Between Catheter-based Coronary Flow and Resistance and 15O-H2O Positron Emission Tomography Scan
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Coronary Physiology|DIAGNOSTIC_TEST: 15O-H2O-PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of ACS in Extreme Preemies
Status: WITHDRAWN
Conditions: Preterm Labor|Premature Birth
Interventions: DRUG: Betamethasone|GENETIC: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms|HER2/Neu Positive|Geriatric Health Services
Interventions: DRUG: Lapatinib|DRUG: Trastuzumab|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Response Effects of Whole Body Vibration on Spasticity and Walking in SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: PROCEDURE: Short Duration|PROCEDURE: Long Duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel (Abraxane) With or Without Mifepristone in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: mifepristone|DRUG: placebo|DRUG: nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Preventive Regimens Containing Different Toothpastes on Caries Risk of High Risk Patients: A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Prevention of Dental Caries
Interventions: OTHER: dual Zinc plus Arginine based toothpaste (Colgate total)|OTHER: Zinc based toothpaste (Crest complete)|OTHER: Fluoride based toothpaste (Signal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Psychotic Disorder, Not Otherwise Specified|Prodromal Schizophrenia|Mood Disorder|Bipolar Disorder|Major Depressive Disorder|Depressive Disorder, Not Otherwise Specified|Mood Disorder, Not Otherwise Specified|Autism Spectrum Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Safety and Pharmacokinetic Study of Gamitrinib Administered Intravenously to Patients With Advanced Cancer
Status: SUSPENDED
Conditions: Lymphoma|Advanced Solid Tumor
Interventions: DRUG: Gamitrinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques
Status: RECRUITING
Conditions: Pulpitis - Irreversible
Interventions: DEVICE: sonic activator|DEVICE: LASER activation|DEVICE: Ultrasonic activation|DEVICE: passive irrigation with Endodontic needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Efficacy (Immunogenicity) and Safety of Euvichol in Healthy Adults and Children
Status: COMPLETED
Conditions: Prevention Harmful Effects
Interventions: BIOLOGICAL: Euvichol|BIOLOGICAL: Shanchol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Dose Escalation Study of VELCADE® and Docetaxel in Patients With Advanced Androgen-Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: VELCADE TM (bortezomib) for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Smoking Cessation|Tobacco Use
Interventions: DEVICE: Active deep transcranial magnetic stimulation (dTMS)|DEVICE: Sham dTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Therapy of COVID-19 in Severely Ill Patients
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Convalescent Plasma (anti-SARS-CoV-2 plasma)|BIOLOGICAL: Non-convalescent Plasma (control plasma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the In-plane and Out of Plane Ultrasound Guided Approach for Internal Jugular Vein Cannulation in the Patients Undergoing Elective Cardiac Surgery.
Status: COMPLETED
Conditions: Catheterization, Central Venous|Ultrasonography|Cardiac Surgical Procedures
Interventions: PROCEDURE: In-plane Axis|PROCEDURE: Out of plane Axis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Perioperative Glycemia Protocol on Glycemic Outcomes in Diabetic Patients Undergoing Abdominal Surgery
Status: COMPLETED
Conditions: Hyperglycemia|Perioperative Complication
Interventions: OTHER: glycaemic management protocol implemented to clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety of 3 New 6:2 Influenza Virus Reassortants in Adults for the 2015-2016 Season
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism
Status: COMPLETED
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Prebiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Valsalva Manoeuvre and Intravenous Dexmedetomidine on Attenuating Pain During Propofol Injection in Upper GIT Endoscopy
Status: COMPLETED
Conditions: Injection Site Irritation
Interventions: OTHER: Valsalva Manoeuvre|DRUG: Dexmedetomidine Injection [Precedex]|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: GRID Therapy as Palliative Radiation for Patients With Advanced and Symptomatic Tumors
Status: RECRUITING
Conditions: Patients With Symptomatic or Bulky Tumors (More Than 8 cm) or With Tumors Resistant to Radiation
Interventions: RADIATION: spatially fractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome (SIRS)|Postoperative Vasodilation Syndrome|Stress Response|Cardiac Surgery Prognosis|Tissue Oxygenation and Post-ischemic Response
Interventions: DIAGNOSTIC_TEST: Preoperative copeptin level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Lidocaine in Antiarrhythmic Dosage on Postoperative Cognitive Dysfunction in Supratentorial Craniotomy Dysfunction in Supratentorial Craniotomy
Status: COMPLETED
Conditions: Supratentorial Craniotomy Dysfunction
Interventions: DRUG: lidocaine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Non-inferiority Phase 2 Study to Evaluate the Safety and Efficacy of PEG-rhGH in the Treatment of AGHD
Status: UNKNOWN
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: Somatropin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Targets in Patients With Bladder Emptying Difficulties
Status: COMPLETED
Conditions: Neurogenic Bladder|Multiple Sclerosis|Voiding Dysfunction
Interventions: DEVICE: Transcranial Rotating Permanent Magnet Stimulator (TRPMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kui-Yuan Chewable Tablets in Patients With Hyperuricemia
Status: NOT_YET_RECRUITING
Conditions: Hyperuricemia
Interventions: DRUG: Kui-Yuan Chewable Tablets|DRUG: Placedo of Kui-Yuan Chewable Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DNIB0600A in Comparison With Pegylated Liposomal Doxorubicin (PLD) in Participants With Platinum-Resistant Ovarian Cancer (PROC)
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: DNIB0600A|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Study of a Single Dose Bisoprolol Versus Nebivolol in Healthy Subjects
Status: WITHDRAWN
Conditions: Bisoprolol Adverse Reaction|Nebivolol Adverse Reaction
Interventions: DRUG: Bisoprolol versus Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Drug Interaction Study Between AZD3480 and Cytochrome P450
Status: COMPLETED
Conditions: Metabolism|Alzheimer's Disease
Interventions: DRUG: AZD3480|DRUG: Placebo|DRUG: Cocktail mix (Caffeine, Bupropion, Rosiglitazone, Omeprazole, Midazolam, Bilirubin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Arthroscopic Treatment With Ulnar Nerve Release for Elbow Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Primary Osteoarthritis, Elbow|Ulnar Nerve Release
Interventions: DEVICE: ulnar nerve mini open release|DEVICE: without ulnar nerve mini open release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Diuretics With Change in Extracellular Volume, Natriuretic Peptides, Symptoms, and Cardiovascular Outcomes in CKD
Status: WITHDRAWN
Conditions: Chronic Kidney Disease
Interventions: DRUG: Diuretic initiation or augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for Subjects With RPGR Mutation-associated X-linked Retinitis Pigmentosa
Status: RECRUITING
Conditions: X-Linked Retinitis Pigmentosa
Interventions: GENETIC: FT-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety of SAR342434 and Humalog® When Administered as Continuous Subcutaneous Insulin Infusion
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: SAR342434|DRUG: insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia
Status: COMPLETED
Conditions: Postmenopausal Osteopenia
Interventions: OTHER: Kinect Based Virtual Reality Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacists Improving Refugees' Adherence and Knowledge of Their Chronic Medications
Status: COMPLETED
Conditions: Diabetes|Hypertension|Dyslipidemias|Cardiac Disease|Asthma
Interventions: OTHER: Medication Management Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preoxygenation With High Flow Nasal Cannula Prolongs Normoxia Time During Induction of Anaesthesia of Bariatric Patients and is Superior to Conventional Preoxygenation With Face Mask.
Status: UNKNOWN
Conditions: Compare Preoxygenation Methods in Bariatric Patients
Interventions: OTHER: Preoxygenation with High Flow Nasal Cannula|OTHER: Preoxygenation via face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Understanding Post-translational Modifications to Circulating Histones Via Mass Spectrometry in Pregnant Women Developing Pre-eclampsia: A Retrospective Study
Status: COMPLETED
Conditions: Pregnancy Related|Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: Analysis of post-translational histone modifications via mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Project inCharge: Increasing the Rate of Comprehensive Eye Care Utilization by Older African Americans Through Community-Based Eye Health Education Program
Status: COMPLETED
Conditions: Eye Disease|Eye Care|Vision
Interventions: BEHAVIORAL: Eye care education|BEHAVIORAL: Social-contact control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Valsartan vs Perindopril on HOMA-IR Index in Patients With Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: DRUG: Valsartan|DRUG: Perindopril
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of S-Adenosylmethionine in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DIETARY_SUPPLEMENT: SAM-e (S-Adenosyl-L-Methionine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT