pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Pharmacokinetic (PK) Study Of PF-00299804 And Dextromethorphan In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: reference [dextromethorphan]|DRUG: test [PF-00299804 + dextromethorphan]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986325 in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of High Flow Therapy on Complications Related to Airway Stenting
Status: RECRUITING
Conditions: Airway Obstruction|Respiratory Infection|Mucus; Plug
Interventions: DEVICE: High flow nasal cannula|DEVICE: nebulized normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individual Versus Group-based Exercise Rehabilitation for Shoulder Disorders: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: BEHAVIORAL: Group-based exercise rehabilitation|BEHAVIORAL: Individual exercise rehabilitation|BEHAVIORAL: Home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplant in Treating Patients With High-Risk Leukemia
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methylprednisolone|DRUG: therapeutic allogeneic lymphocytes|DRUG: thiotepa|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: biological therapy|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: bone marrow transplantation|PROCEDURE: chemotherapy|PROCEDURE: leukocyte therapy|PROCEDURE: non-specific immune-modulator therapy|PROCEDURE: peripheral blood lymphocyte therapy|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Tissue Engineering With Dental Pulp Stem Cells for Alveolar Cleft Repair
Status: COMPLETED
Conditions: Cleft Lip and Palate
Interventions: COMBINATION_PRODUCT: Mesenchymal stem cells associated with biomaterials|COMBINATION_PRODUCT: Iliac crest autogenous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With HCV Who Failed a Prior DAA Containing Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis C Virus|HCV|Direct-Acting Antiviral Agent (DAA)-Experienced
Interventions: DRUG: ABT-493, ABT-530|DRUG: ribavirin (RBV)|DRUG: ABT-493/ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Status: COMPLETED
Conditions: Deformity|Defect, Congenital|Trauma
Interventions: DEVICE: JuniOrtho™ Plating System™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lenalidomide With or Without Ixazomib Citrate and Dexamethasone in Treating Patients With Residual Multiple Myeloma After Donor Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasma Cell Myeloma|Residual Disease
Interventions: DRUG: Ixazomib Citrate|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Recurrent Adrenocortical Carcinoma|Stage III Adrenocortical Carcinoma|Stage IV Adrenocortical Carcinoma
Interventions: BIOLOGICAL: IMC-A12|DRUG: mitotane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D3 for Aromatase Inhibitor Induced Arthralgias
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: High Dose Vitamin D|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Standard Dose Vitamin D3|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: REVEAL III: Risk Evaluation and Education for Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Pleiotropic info, in-person disclosure|BEHAVIORAL: AD-only info, in-person disclosure|BEHAVIORAL: Pleiotropic info, phone disclosure|BEHAVIORAL: AD-only info, phone disclosure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sorafenib VS TACE in HCC Patients With Portal Vein Invasion
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: TACE for HCC with portal vein invasion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: CT041 autologous CAR T-cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Sildenafil in Patients With Erectile Dysfunction Receiving Hemodialysis
Status: COMPLETED
Conditions: Erectile Disfunction|Hemodialysis
Interventions: DRUG: placebo|DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acid on Cortical Function in ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder
Interventions: DRUG: DHA Omega-3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration Combined With L-citrulline Supplementation on Cardiovascular Function and Body Composition
Status: COMPLETED
Conditions: Obesity|Pre-hypertension|Hypertension
Interventions: DIETARY_SUPPLEMENT: L-citrulline supplementation|OTHER: Whole Body Vibration Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neural and Behavioral Outcomes of Social Skills Groups in Children With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Play Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Acupuncture for Insulin Resistance in Patients With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome (PCOS)
Interventions: OTHER: lifestyle intervention|DEVICE: acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Belatacept in Heart Transplantation
Status: NOT_YET_RECRUITING
Conditions: Heart Transplant
Interventions: DRUG: Belatacept|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil/Sodium|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Clinical Study of the Sonablate®450 for the TreAtment of Locally Recurrent Prostate Cancer With HIFU (STAR Trial)
Status: UNKNOWN
Conditions: Recurrent Prostate Cancer
Interventions: DEVICE: High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Improve Functional Outcome and Persistent Symptoms in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Behavior Therapy for Psychosis|BEHAVIORAL: Cognitive Adaptation Training|BEHAVIORAL: Multi-modal Cognitive Therapy|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety of AV-1, an Antibody Being Developed for Treatment of Dengue, in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AV-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: JNJ-77242113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children
Status: COMPLETED
Conditions: Antibiotic Associated Diarrhea
Interventions: DRUG: Lactobacillus reuteri DSM 17938|DRUG: Placebo|DRUG: Amoxicillin-Clavulanic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of New Product Standards for JUUL Among Dual JUUL/Combusted Cigarette Users
Status: WITHDRAWN
Conditions: Smoking|E-cigarette Use|Cigarette Smoking
Interventions: OTHER: 5% nicotine content JUUL pod|OTHER: 3% nicotine content JUUL pod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Health at Every Size vs a Behavioral Weight Loss Approach for Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Wellness-Centered (HUGS)|BEHAVIORAL: Weight-Centered (LEARN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: Control toothpaste containing Novamin® technology|DRUG: Control toothpaste containing 1500 ppm fluoride as MFP|DRUG: Test toothpaste with nano-HAP (high concentration)|DRUG: Test toothpaste with nano-HAP (low concentration)|DRUG: Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3|DRUG: Control toothpaste without nano-HAP|DRUG: Test toothpaste with nano-HAP (medium concentration)|DRUG: Test cream with nano-HAP (higher concentration)|DRUG: Control cream without nano-HAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration
Status: UNKNOWN
Conditions: Defect; Internal Prosthetic Device, Implants and Grafts, Orthopedic, Bone Graft
Interventions: PROCEDURE: 3D printing implant|PROCEDURE: autogenous bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Secondary Hyperparathyroidism With Vitamin D in Stage II/III Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bicentric Clinical Investigation to Assess Safety and Performance of LuxHighAdd IOL
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: DEVICE: LuxHighAdd IOL|DEVICE: LuxGood IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AV0328 Administered to Healthy Adult Volunteers
Status: COMPLETED
Conditions: PNAG-expressing Pathogenic Microbes Vaccine
Interventions: BIOLOGICAL: AV0328 - Cohort 1|BIOLOGICAL: AV0328 - Cohort 2|BIOLOGICAL: AV0328 - Cohort 3|BIOLOGICAL: AV0328 - Cohort 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preventing Inadvertent Hypothermia in Paediatric Neurosurgery in Malawi
Status: COMPLETED
Conditions: Hypothermia
Interventions: OTHER: Hibler's|OTHER: Warm Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biological Standardization of Poa Pratensis Allergen Extract
Status: COMPLETED
Conditions: Allergy to Grass Pollen
Interventions: BIOLOGICAL: Four different concentrations of Poa pratensis allergen extract, positive control and negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Benefits of Hemp Protein Supplementation During Resistance Training
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Hemp powder|DIETARY_SUPPLEMENT: Soy Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial to Reduce Antimicrobial Use In Nursing Home Residents With Alzheimer's Disease and Other Dementias
Status: COMPLETED
Conditions: Dementia|Infection, Bacterial
Interventions: BEHAVIORAL: TRAIN-AD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study Assessing the Safety and Tolerability
Status: WITHDRAWN
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Laquinimod 0.6|DRUG: Laquinimod 1.2|OTHER: Glatiramer Acetate or interferon-beta+ Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Therapy in Patients With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|Tennis Elbow
Interventions: DRUG: Hyaluronic Acid|BIOLOGICAL: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Comparing MR-guided in Bore Versus MRI/US Fusion-guided Prostate Biopsy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: MR-guided in-bore prostate biopsy|DEVICE: MRI/US fusion-guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas
Status: TERMINATED
Conditions: Neurofibromatosis|NF1|Plexiform Neurofibromas
Interventions: DRUG: Sutent®/Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine for the Treatment of Depression in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease|Depression
Interventions: DRUG: Ketamine Infusion|OTHER: Placebo - Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer|Endometrial Cancer|Recurrent Ovarian Cancer|Recurrent Endometrial Cancer
Interventions: DRUG: BKM120|DRUG: Nabpaclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and CAPOX in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Azacitidine|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Azacitidine MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Lesioning Splanchnic Nerves in Patients With Chronic Pancreatitis
Status: UNKNOWN
Conditions: Chronic Pancreatitis|Chronic Pain|Abdominal Pain
Interventions: PROCEDURE: Percutaneous Radiofrequent Lesioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.
Status: RECRUITING
Conditions: Recurrent Acute Pancreatitis
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Micro-Manipulation Procedures for Assisted Hatching Timing
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: OTHER: Laser Assisted Hatching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reproductive Outcomes of Different Sperm Selection Techniques for ICSI Patients With Abnormal Sperm DNA Fragmentation.
Status: COMPLETED
Conditions: Infertility, Male
Interventions: OTHER: Density Gradient Centrifugation|OTHER: Physiological ICSI|OTHER: Magnetic activated cell sorting|OTHER: Testicular sperm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Participatory System Dynamics vs Usual Quality Improvement: Staff Use of Simulation as an Effective, Scalable and Affordable Way to Improve Timely Mental Health Care?
Status: ENROLLING_BY_INVITATION
Conditions: PTSD|Depression|Opioid Use Disorder
Interventions: BEHAVIORAL: Modeling to Learn (MTL)|BEHAVIORAL: Usual quality improvement (QI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events
Status: ACTIVE_NOT_RECRUITING
Conditions: Frailty|Motoric Cognitive Risk Syndrome|Cognitive-prefrailty
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eight Week Study of Treatment With DFD-07 for Actinic Keratosis of the Face and Scalp
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: DFD-07 Cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Surgical Decisions and Prognosis of the Radiomics and Watson Artificial Intelligence in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Liver Resection
Interventions: DEVICE: Radiomics and Watson artificial intelligence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy in Treating Patients With Primary Stage I Non-Small Cell Lung Cancer or Lung Metastasis
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: PROCEDURE: Cryotherapy (PTC)|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Flavopiridol in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy of Carglumic Acid in Organic Acidemia.
Status: UNKNOWN
Conditions: Propionic Acidemia (PA) , Methylmalonic Acidemia (MMA)
Interventions: DRUG: Carglumic Acid (Carbaglu®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Pemetrexed/ Carboplatin in Patients With Brain Metastases of Non-squamous NSCLC
Status: COMPLETED
Conditions: NSCLC Stage IV|Brain Metastases|PD-1 Antibody
Interventions: DRUG: Tislelizumab, Carboplatin, Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Obinutuzumab|OTHER: Patient Observation|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)|Colorectal Cancer (CRC)|Pancreatic Ductal Adenocarcinoma|Advanced Solid Tumor
Interventions: DRUG: RMC-6291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Primary Care Hypoglycemia Prevention Program
Status: RECRUITING
Conditions: Diabetes Mellitus|Hypoglycemia
Interventions: OTHER: Patient Group (Hypoglycemia Prevention Program)|OTHER: Primary Care Physician Group|OTHER: Clinic Staff Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pain Neuroscience Education and Behavioural Graded Activity on Chronic Pain in Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms|Survivors|Chronic Pain
Interventions: OTHER: Pain Neuroscience Education|OTHER: Behavioural Graded Activity|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Therapy With CD137L-DC-EBV-VAX in Locally Advanced Stage IV or Locally Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Cancer
Interventions: BIOLOGICAL: CD137L-DC-EBV-VAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Liposomal Amphotericin B in Critically Ill vs. Non-critically Ill Hematological Patients: Exploration of Covariates
Status: RECRUITING
Conditions: Pharmacokinetics|Liposomal Amphotericin B|Critically Ill Patients
Interventions: OTHER: Sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis
Interventions: DRUG: zoledronic acid|PROCEDURE: Letrozole as adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adoptive Transfer of pp65-specific T Cells for the Treatment of Refractory Cytomegalovirus (CMV) Infection
Status: WITHDRAWN
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: IFN-γ positive selected T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars
Status: UNKNOWN
Conditions: Acne Scars
Interventions: DEVICE: Fraxel Restore (Non-ablative Fractional Laser)|DEVICE: Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application Breathing Exercises With Load Inspiratory Postoperative Abdominal Surgery
Status: COMPLETED
Conditions: Pulmonary Atelectasis|Respiratory Tract Diseases|Pathological Conditions, Signs and Symptoms
Interventions: PROCEDURE: incentive spirometry|PROCEDURE: inspiratory load equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Method of Clipped Axillary Lymph Node Localization Post Neoadjuvant Chemotherapy in Breast Cancer Patients .
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: PROCEDURE: skin marking of clip axillary lymph node for localisation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open Trial With Subcutaneous Immunotherapy (SCIT) in Patients With Rhinoconjunctivitis Sensitized to Parietaria Judaica
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: BIOLOGICAL: Allergovac depot with Parietaria judaica pollen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis
Status: UNKNOWN
Conditions: Diarrhea
Interventions: DRUG: ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Suction in the EUS-guided Fine Needle Biopsy of Solid Pancreatic Lesions
Status: UNKNOWN
Conditions: Biopsy, Fine-Needle|Endosonography|Pancreatic Neoplasm
Interventions: DEVICE: EUS-guided FNB with Syringe Suction|DEVICE: EUS-guided FNB without Syringe Suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Status: TERMINATED
Conditions: Psychiatric/Mood Disorder | Patient|Estrogen Receptor Levels|Premenopausal|Postmenopausal
Interventions: PROCEDURE: FES-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Supporting Caregivers of PWD and Identifying an Effective Intervention to Reduce Their Depressive Symptoms
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Smartphone delivered Behavioral activation|BEHAVIORAL: Smartphone delivered Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamics, Pharmacokinetics and Safety of Two Doses of CHF6001 DPI in Subjects With Moderate, Severe COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: CHF 6001 Dose1|DRUG: CHF 6001 Dose2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C Mill Virtual Reality Applied Rehabilitation and Classical Rehabilitation on Gait and Balance in Parkinson's Patients
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson Disease|Rehabilitation
Interventions: PROCEDURE: classical physical therapy with physiotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing The Bioequivalence Of Ciclesonide Nasal Spray (Apotex, Inc.) To That Of Omnaris™ Nasal Spray (Sepracor, Inc.) In The Treatment Of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Ciclesonide nasal spray, 50 μg per actuation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RFT5-dgA Immunotoxin in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: RFT5-dgA immunotoxin|OTHER: fluorescence activated cell sorting|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Drug Combinations Against Triple Infections
Status: COMPLETED
Conditions: Parasitic Diseases
Interventions: DRUG: albendazole + ivermectin + praziquantel|DRUG: albendazole + ivermectin + (1 week later) praziquantel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.
Status: NOT_YET_RECRUITING
Conditions: Fibroid Uterus
Interventions: DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Drug Eluting TACE in Primary HCC
Status: UNKNOWN
Conditions: Hepatic Cell Carcinoma
Interventions: DRUG: HepaSphere Microspheres/Doxorubicin Hydrochloride|DRUG: Lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation to Improve Cancer Surgery Outcomes
Status: UNKNOWN
Conditions: Gastrointestinal Cancer|Prehabilitation|Surgery|Physical Activity
Interventions: BEHAVIORAL: Physical Prehabilitation|BEHAVIORAL: Psychological Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Positron emission tomography (PET)|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of Weekly Intravenous (IV) Doses of BMS-906024 in Subjects With Acute T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute T-cell|Precursor T-Cell Lymphoblastic Lymphoma
Interventions: DRUG: BMS-906024|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy
Status: TERMINATED
Conditions: Advanced Solid Tumors|Hepatocellular Carcinoma
Interventions: DRUG: Pimasertib|DRUG: Pimasertib|DRUG: Pimasertib|DRUG: Pimasertib|DRUG: Pimasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follicular Synchronization in PCOS Patients Undergoing ICSI
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: letrozole 2.5mg (Femara; Novartis Pharma Services, Basel, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Investigational Treatment in Patients With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: AT193
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Tritanrix-HepB/Hib-MenAC, Tritanrix-HepB/Hiberix, and Mencevax ACWY Vaccines in Children
Status: COMPLETED
Conditions: Whole Cell Pertussis|Tetanus|Hepatitis B|Diphtheria|Haemophilus Influenzae Type b|Diphtheria-Tetanus-Pertussis-Hepatitis B-Haemophilus Influenzae Type b-Neisseria Meningitidis Vaccin
Interventions: BIOLOGICAL: Tritanrix-HepB/Hib-MenAC|BIOLOGICAL: Tritanrix-HepB/Hiberix|BIOLOGICAL: Mencevax-ACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: OTHER: lymph nodes cyto-punction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects
Status: COMPLETED
Conditions: Trypanosomiasis, African|Trypanosoma Brucei Gambiense; Infection|Sleeping Sickness
Interventions: DRUG: Acoziborole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synchronous and Asynchronous Telerehabilitation Methods in Patients With Shoulder Tendinopathy
Status: UNKNOWN
Conditions: Tendinopathy|Shoulder Pain
Interventions: OTHER: Synchronous Exercise Program|OTHER: Asynchronous Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ATI-450 50 mg oral tablet BID|DRUG: Placebo oral tablet|DRUG: Methotrexate|DRUG: ATI-450 20 mg oral tablet BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy
Status: ENROLLING_BY_INVITATION
Conditions: Peanut Allergy|Peanut Hypersensitivity|Peanut-Induced Anaphylaxis|Immune System Diseases
Interventions: BIOLOGICAL: PVX-108|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Mindfulness Programme on Competitive Athletes With Physical Disabilities
Status: COMPLETED
Conditions: Athletic Injuries|Physical Disability|Chronic Pain
Interventions: OTHER: Experimental group (MSPE programme group).|OTHER: Control group (relaxation group).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trimethoprim-Sulfamethoxazole vs Levofloxacin as Targeted Therapy for Stenotrophomonas Maltophilia Infections: a Retrospective Cohort Study
Status: COMPLETED
Conditions: Stenotrophomonas Infection
Interventions: DRUG: Levofloxacin|DRUG: trimethoprim-sulfamethoxazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aortic Valve and Root Measurements Under Real-Time 3-Dimensional Visualization During Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Stenosis
Interventions: RADIATION: Real-time 3-dimensional DynaCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Incidence of Regurgitation in Patients Undergoing Intubation in Semi-fowler v/s Supine Position
Status: RECRUITING
Conditions: Inguinal Hernia Bilateral
Interventions: PROCEDURE: Incidence of regurgitation in two different position.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A 38 Week Trial Comparing Effect and Safety of Insulin Degludec/Insulin Aspart vs. Insulin Glargine Plus Insulin Aspart in Subjects With Type 2 Diabetes Treated With Basal Insulin With or Without Oral Antidiabetic Treatment in Need of Treatment Intensification
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec/insulin aspart|DRUG: Insulin glargine|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stepped Care Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder|Stepped Care Cognitive Behavioral Therapy
Interventions: BEHAVIORAL: Stepped Care Cognitive Behavioral Therapy|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of SM03 in Patients With Rheumatoid Arthritis Receiving Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SM03|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GASC1 Inhibitor Caffeic Acid for Squamous Esophageal Cell Cancer (ESCC)
Status: UNKNOWN
Conditions: Esophagus Cancer, Stage III
Interventions: DRUG: Caffeic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone at Night vs at Induction on PONV After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Postoperative Pain|Laparoscopic Cholecystectomy
Interventions: DRUG: At-night Dexamethasone|DRUG: At-induction Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: NAC (Nutritional Assessment and Counseling)|OTHER: Cash Transfer|OTHER: Food Assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DHA and Vitamin D in Children With Biopsy-proven NAFLD
Status: COMPLETED
Conditions: NAFLD|Non Alcoholic Steatohepatitis (NASH)
Interventions: DRUG: DHA plus Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
Status: COMPLETED
Conditions: Diverticulum, Colon|Colorectal Neoplasms|Crohn Disease|Colitis, Ulcerative|Colostomy|Ileostomy - Stoma|Rectal Prolapse|Intestinal Polyposis|Lymphoma|Endometriosis|Intestinal Volvulus
Interventions: DEVICE: ColonRing™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
Status: NOT_YET_RECRUITING
Conditions: Basal Ganglia Germinoma|Central Nervous System Germinoma|Diabetes Insipidus|Pineal Region Germinoma|Suprasellar Germinoma|Thalamic Germinoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Etoposide|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Lumbar Puncture|PROCEDURE: Magnetic Resonance Imaging|OTHER: Questionnaire Administration|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Analyzing Effects of Prokinetic Drug on the Blood Glucose in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Mosapride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-RM2 PET/CT in Detecting Regional Nodal and Distant Metastases in Patients With Intermediate or High-Risk Prostate Cancer
Status: COMPLETED
Conditions: Stage II Prostate Adenocarcinoma|Stage III Prostate Adenocarcinoma|Stage IV Prostate Adenocarcinoma
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-labeled GRPR Antagonist BAY86-7548|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Profile of Betahistine With and Without Selegiline in Healthy Volunteers
Status: COMPLETED
Conditions: Ménière's Disease
Interventions: DRUG: Betahistine dihydrochloride|DRUG: Selegiline-hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Magnitude of Effect of PCP Counseling on Participation Rate and Sedation Rate in Colonoscopy-based Screening Program
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: OTHER: Physician's counseling|OTHER: Information leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Multisystem Exercise on Balance, Postural Stability, Mobility and Pain in Patients With DPN.
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Multisystem Exercise|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Furosemide Stress Test Guiding Initiation of Renal Replacement Therapy
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DEVICE: Dialysis with continuous renal replacement therapy|DEVICE: Mechanical ventilator|DRUG: Anti-Bacterial Agents|DRUG: Vasopressors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rechargeable Implantable Vagus Nerve Stimulation System for Drug-Refractory Epilepsy
Status: RECRUITING
Conditions: Drug-Refractory Epilepsy
Interventions: DEVICE: G114R VNS system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK2578 in Patients With Chronic Kidney Disease Who Are Not on Dialysis (2578-002)
Status: TERMINATED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: MK2578|DRUG: MK2578|DRUG: MK2578|DRUG: Comparator: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liq-NOL Efficacy in Pediatric Patients With Down Syndrome
Status: WITHDRAWN
Conditions: Down Syndrome
Interventions: DIETARY_SUPPLEMENT: Ubiquinol-10 Syrup|DIETARY_SUPPLEMENT: syrup (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT