pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of the Combination of Anti-OX40 and Ipilimumab in Patients With Metastatic Melanoma
Status: WITHDRAWN
Conditions: Metastatic Melanoma
Interventions: DRUG: Anti-OX40|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms|Adenocarcinoma
Interventions: DRUG: JNJ-69086420
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment
Status: COMPLETED
Conditions: Dementia|Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: In-Home Technology System and Questionnaires|DEVICE: Waiting Control In-Home Technology System and Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 2 Regimens of Lactulose for Colonoscopy Preparation in Adults
Status: COMPLETED
Conditions: Colonoscopy Preparation
Interventions: DRUG: Full dose preparation|DRUG: Split dose preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy
Status: RECRUITING
Conditions: Gastric Cancer|Reflux Esophagitis
Interventions: PROCEDURE: proximal gastrectomy combined with 'λ+α' double-tract anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Status: COMPLETED
Conditions: Intraabdominal Abscess After Procedure|Leakage|Pneumonia|Operation Wound; Infection
Interventions: PROCEDURE: Peritoneal irrigation|PROCEDURE: Suction only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Canadian Open-Label Access Program to Evaluate Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Humira (adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Mosunetuzumab (Cohorts A-C)|DRUG: Mosunetuzumab (Cohorts D-E)|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and Change in Disease Activity of HArmonyCa Lidocaine Injectable Gel for Mid Face Soft Tissue Augmentation in Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Mid Face Volume Deficit
Interventions: DEVICE: HArmonyCa Lidocaine Injectable Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Early Stage Study to Evaluate Oba01 for Injection in Patients With DR5 Positive LA/mNSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Oba01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of Duvortuxizumab in Participants With Relapsed or Refractory B-cell Malignancies
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Follicular|Lymphoma, Mantle-Cell|Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Part 1 (Dose Escalation): Duvortuxizumab|DRUG: Part 2 (Dose Expansion): Duvortuxizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sequential Allocation Study to Determine the ED50 of Dexmetedomidine as an Adjuvant to Lidocaine Intravenous Regional Anesthesia
Status: COMPLETED
Conditions: Bier Block|Dexmedetomidine|Tourniquet Pain|Carpal Tunnel|Tendon Release|Tendn Transfer
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Transcranial Photobiomodulation Intervention for Healthy Older Adults
Status: COMPLETED
Conditions: Transcranial Photobiomodulation|Intervention|Functional Near-infrared Spectroscopy|Working Memory|Healthy Older Adults
Interventions: BEHAVIORAL: Active tPBM session|BEHAVIORAL: Sham tPBM session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Time Performance of Scoop Stretcher Versus Vacuum Mattress for Prehospital Spinal Stabilization
Status: COMPLETED
Conditions: Immobilization
Interventions: DEVICE: Scoop stretcher|DEVICE: Vacuum mattress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Factors Study to Validate the User Interface of TOBI Podhaler Using Placebo Capsules
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Placebo|DEVICE: Tobi Podhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Etodolac Tablet USP 500 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Etodolac Tablets USP 500mg|DRUG: Etodolac Tablets USP 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MitraClip REPAIR MR Study
Status: RECRUITING
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: MitraClip™ device implantation|PROCEDURE: Mitral Valve Repair Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thermal Ablation of Cervical Metastases From Thyroid Carcinoma
Status: RECRUITING
Conditions: Thyroid Neoplasia|Well-Differentiated Thyroid Cancer|Medullary Thyroid Cancer|Lymph Node Metastases
Interventions: DEVICE: Laser ablation|DEVICE: Cryoablation|DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inforatio Technique to Promote Wound Healing of Diabetic Foot Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot Ulcer|Diabetes|Foot Ulcer|Diabetic Foot|Diabetes Complications|Diabetes Mellitus
Interventions: PROCEDURE: Inforatio technique|OTHER: Usual care of the respective outpatient clinics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Arabinoxylan and Rye Kernels on Second Meal Responses
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Arabinoxylan|DIETARY_SUPPLEMENT: Rye kernel|DIETARY_SUPPLEMENT: Arabinoxylan and rye kernels|DIETARY_SUPPLEMENT: Semolina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy
Status: NOT_YET_RECRUITING
Conditions: Demyelinating Diseases|Demyelination; Corpus Callosum|Multiple Sclerosis Brain Lesion|Multiple Sclerosis Acute and Progressive|Clinically Isolated Syndrome, CNS Demyelinating
Interventions: DRUG: Clemastine Fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ropivacaine (With Epinephrine) in BABA Endoscopic and Robotic Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Neoplasm|Goiter
Interventions: DRUG: Ropivacaine with epinephrine injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Somatostatin Receptor Imaging Using PET/MRI as a Novel Approach to Detecting Pathology in Pulmonary TB
Status: UNKNOWN
Conditions: Tuberculosis
Interventions: OTHER: 68Ga-DOTANOC PET/MRI|OTHER: 18F-FDG PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics and Pharmacodynamics Clinical Study of VC005 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: VC005 Tablets|DRUG: VC005 Tablets Placebo|DRUG: VC005 Tablets food effects group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Power Training Combined With Interval Treadmill Training
Status: COMPLETED
Conditions: Cerebral Palsy|Central Nervous System Diseases|Brain Damage, Chronic
Interventions: BEHAVIORAL: Power training combined with interval treadmill training|BEHAVIORAL: Strength training combined with traditional treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of YHD1023 in Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: YHD1023|DRUG: YHD1023|DRUG: YHD1023|DRUG: Cialis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characteristics of Rheumatoid Arthritis Patients With Atlantoaxial Synovitis Detected by Plain X-ray and MRI
Status: WITHDRAWN
Conditions: Neck Pain
Interventions: RADIATION: Plain X-ray|RADIATION: Magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ComParative Diagnostic Study Between Multislice Computed Tomography (MSCT) and Stress Echography in Coronarin Patients.
Status: COMPLETED
Conditions: Chest Pain
Interventions: PROCEDURE: MSCT and stress echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Status: RECRUITING
Conditions: Prevention of Ischemic Stroke|Acute Non-cardioembolic Ischemic Stroke|High-risk Transient Ischemic Attack
Interventions: DRUG: Asundexian (BAY2433334)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Impact of Cholecystectomy on Gut Microbiome in Adults
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective Randomized Controlled Study Comparing the Clinical Effects of Surgical and Non-surgical Treatment of Low Rib Fractures
Status: NOT_YET_RECRUITING
Conditions: Rib Fracture Multiple
Interventions: PROCEDURE: surgical stabilization of low rib fratures|OTHER: converstive treatment of low rib fratures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Spherical Soft Contact Lenses, Toric Soft Contact Lenses and Spectacles in Low Astigmats
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE Oasys 1-Day with HydraLuxe Technology for Astigmatism|DEVICE: ACUVUE Oasys 1-Day with HydraLuxe Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib In Combination With Weekly Paclitaxel For Patients With Metastatic Breast Carcinoma CA 180 194
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Dasatinib and Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Flushing With Follicular Fluid Plus Granulosa Cells
Status: COMPLETED
Conditions: Follicular Fluid|Granulosa Cell|Embryo Implantation
Interventions: BIOLOGICAL: Intrauterine flushing of follicular fluid with granulosa cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Vitamin D Encapsulated in Casein Micelles, Compared to Its Bioavailability in the Milk-fat, or in a Synthetic Emulsifier Currently Used for Supplementation and Enrichment
Status: UNKNOWN
Conditions: Healthy Individuals
Interventions: DIETARY_SUPPLEMENT: Group 1|DIETARY_SUPPLEMENT: Group 2|DIETARY_SUPPLEMENT: group 3|DIETARY_SUPPLEMENT: Group 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Application of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Surface Malignancies
Status: RECRUITING
Conditions: Peritoneal Metastases
Interventions: DRUG: Pressured Intraperitoneal Aerosol Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Superficial Inferior Epigastric System in Deep Inferior Epigastric Perforator (DIEP) Flaps
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Both Superficial Inferior Artery and Vein Clamped|PROCEDURE: Superficial Inferior Epigastric Vessels both unclamped|PROCEDURE: SIE Artery Unclamped, Vein Clamped|PROCEDURE: SIE Artery clamped, Vein unclamped
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Efficacy and Safety of Cabotegravir (CAB) Long Acting (LA) Plus (+) Rilpivirine (RPV) LA Versus BIKTARVY® (BIK) in Participants With Human Immunodeficiency Virus (HIV)-1 Who Are Virologically Suppressed
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir Tablets|DRUG: Cabotegravir Injectable Suspension (CAB LA)|DRUG: Rilpivirine Tablets|DRUG: Rilpivirine Injectable Suspension (RPV LA)|DRUG: BIKTARVY Tablets (BIK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Subgingival Air-polishing, as an Adjunct to Non-surgical Periodontal Treatment on Periodontal Parameters and Patient Satisfaction in Patients With Periodontitis
Status: UNKNOWN
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Air-polishing with ultrasonic debridement|PROCEDURE: Conventional scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Coronary Artery Lesions
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Stenosis
Interventions: DIAGNOSTIC_TEST: fractional flow reserve (FFR); ultrasonic flow ratio (UFR); intravascular ultrasound (IVUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Moderate Hepatic Impairment|Normal Hepatic Function
Interventions: DRUG: Rivipansel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity of HPV Vaccine in Transplant Recipients.
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Kidney Transplant
Interventions: BIOLOGICAL: Human Papilloma Virus vaccine (GARDASIL 9)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Single Doses of IV Aerucin in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Aerucin 2.0mg/kg|BIOLOGICAL: Aerucin 8.0mg/kg|BIOLOGICAL: Aerucin 20.0 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Image-Guided Pleural Needle Biopsy in Pleural Diseases
Status: COMPLETED
Conditions: Biopsy|Diagnosis|Pleura; Exudate
Interventions: PROCEDURE: Cutting needle biopsy|PROCEDURE: Abrams needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Varlitinib|DRUG: Capecitabine|DRUG: Placebo (for Varlitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of Paricalcitol in Reducing Serum Intact Parathyroid Hormone in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Botox Versus Tacrolimus in Psoriasis Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Botulinum Toxin-A|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assess Consistency of Immunogenicity of GlaxoSmithKline Biologicals' Pandemic Influenza Vaccine (GSK1562902A) in Adults
Status: COMPLETED
Conditions: Influenza|Influenza Vaccines
Interventions: BIOLOGICAL: H5N1 adjuvanted split virus vaccine (A/Vietnam/1194/2004 strain)|BIOLOGICAL: H5N1 non-adjuvanted split virus vaccine (A/Vietnam/1194/2004 strain)|BIOLOGICAL: H5N1 adjuvanted split virus vaccine (A/Indonesia/05/2005 strain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Progressive Muscle Relaxation Exercises on Premenstrual Syndrome
Status: NOT_YET_RECRUITING
Conditions: Premenstrual Syndrome
Interventions: BEHAVIORAL: Progressive muscle relaxation exercises|BEHAVIORAL: Violent tendency Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Fecal Biotherapy (FBT) on Microbial Diversity in Patients With Moderate to Severe Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Fecal Microbial Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: BIOLOGICAL: Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Antidepressant Treatment for Negative Symptom of Schizophrenia With NRG1 Risk Genotype
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Lexapro|DRUG: Cymbalta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Study of Nab-sirolimus (ABI-009) in Patients With Advanced Malignant PEComa
Status: COMPLETED
Conditions: Malignant PEComa
Interventions: DRUG: nab-Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Exploring The Safety And Efficacy Of Novel Drug Treatment In Subjects With Diabetic Macular Edema (DME)
Status: WITHDRAWN
Conditions: Diabetes Mellitus|Diabetic Retinopathy
Interventions: DRUG: AG-014699
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Enhanced Recovery After Surgery in Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)|Surgery
Interventions: DRUG: Flurbiprofen Axetil|DRUG: Sufentanil|BEHAVIORAL: Extended perioperative counseling|BEHAVIORAL: Shorter fasting food and water time before surgery|BEHAVIORAL: Conventional perioperative counseling|BEHAVIORAL: Regular fasting food and water time before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Kinesiology Taping on Balance in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Balance|Duchenne Muscular Dystrophy
Interventions: DEVICE: Kinesiology tape
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Couple-Based Lifestyle Intervention to Prevent Type 2 Diabetes
Status: COMPLETED
Conditions: PreDiabetes|Prediabetic State|Overweight and Obesity
Interventions: BEHAVIORAL: PreventT2 (Individual intervention)|BEHAVIORAL: PreventT2 Together (Couple-based intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma
Status: TERMINATED
Conditions: Ewing Sarcoma|Sarcoma
Interventions: DRUG: Mithramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise on Post-traumatic Growth Among Health Care Providers With Post-traumatic Stress
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Nature based walk therapy|BEHAVIORAL: Sit in nature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antineoplaston Therapy in Treating Patients With Anaplastic Astrocytoma
Status: COMPLETED
Conditions: Anaplastic Astrocytoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer
Status: TERMINATED
Conditions: Stomach Neoplasms|Oesophageal Junction Cancer|Lower Oesophagus Cancer
Interventions: DRUG: Epirubicin|DRUG: Cisplatin|DRUG: Paclitaxel|PROCEDURE: gastric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Symptoms|Depressive Disorder, Major
Interventions: BEHAVIORAL: Two-week web-based self-help intervention based on principles of positive psychology|BEHAVIORAL: Two-week web-based text messages containing fun facts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
Status: RECRUITING
Conditions: Hypertension|Menopause, Premature|Menopause|Blood Pressure
Interventions: DIAGNOSTIC_TEST: Microneurography to measure muscle sympathetic nerve activity (MSNA)|DIAGNOSTIC_TEST: Baroreflex sensitivity testing|DIAGNOSTIC_TEST: Sympathoexcitatory Maneuvers|DIAGNOSTIC_TEST: Blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: RUCAPARIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Vinorelbine and Bevacizumab in Patients With Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Vinorelbine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: China National Registry of Neuro-Inflammatory Diseases
Status: RECRUITING
Conditions: Multiple Sclerosis|NMO Spectrum Disorder|Clinically Isolated Syndrome|CNS Demyelinating Autoimmune Diseases|Acute Disseminated Encephalomyelitis|Primay Angiitis of the Central Nervous System|Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy
Interventions: DRUG: Intravenous steroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creatine Supplementation and Bone Mass
Status: COMPLETED
Conditions: Osteopenia|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: creatine supplementation|OTHER: exercise training|OTHER: placebo (dextrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The StrokeCog Study: Cognitive Rehabilitation Intervention in Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Stroke Sequelae|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive rehabilitation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa
Status: COMPLETED
Conditions: Pain|Symptomatic Irreversible Pulpitis
Interventions: PROCEDURE: Ethyl chloride|PROCEDURE: 5% lidocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Caregiver Training: Evidence of Its Effectiveness for Cognitive and Functional Improvement in Older Adults
Status: COMPLETED
Conditions: Functional Ability|Cognitive Decline|Older Adults|Healthy Aging
Interventions: BEHAVIORAL: Cognitive Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Forehead Lines (Frontalis)
Status: COMPLETED
Conditions: Frown Lines
Interventions: BIOLOGICAL: DaxibotulinumtoxinA for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Physical Therapy for Sexual Dysfunction in Gynecologic Oncology Survivors
Status: COMPLETED
Conditions: Gynecologic Cancer|Sexual Dysfunction
Interventions: OTHER: Control Arm|OTHER: Physical Therapy Arm|OTHER: European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30)|OTHER: Female Sexual Function Index (FSFI)|OTHER: Exit Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Theory-Based Patient Portal eLearning Program for Older Adults With Chronic Illnesses
Status: COMPLETED
Conditions: Patient Portals|Chronic Disease|Older Adults
Interventions: OTHER: Theory-based PP eLearning Program(T-PeP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Processing Integration in Neurological Patients Using fMRI
Status: NOT_YET_RECRUITING
Conditions: Acute Inflammatory Demyelinating Polyradiculoneuropathy|Stroke|Anosognosia|Central and Peripheral Neurodegenerative Pathologies|Neuropsychiatric Conditions
Interventions: DEVICE: 3 Tesla Siemens Skyra MRI scanner
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of a Self-hyPnOsis Practice on Chronic StresS Among Caregivers of Elderly People With Loss of Autonomy at Home
Status: NOT_YET_RECRUITING
Conditions: Stress
Interventions: OTHER: Self-hypnosis|OTHER: Control (Waiting list)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radio-frequency (RF)-Based Plasma Micro-tenotomy for the Treatment of Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Rotator Cuff Shoulder Syndrome and Allied Disorders
Interventions: PROCEDURE: RF micro-tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Participants With Recurrent or Metastatic Squamous Cell Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Pemetrexed|DRUG: Cetuximab|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing 80 mg of Adalimumab With Placebo, and Demonstrating the Non-inferiority of Monthly 80 mg Adalimumab Dosing Compared With 40 mg Adalimumab Every Other Week Dosing
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: adalimumab|DRUG: Placebo|DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Bright-light Exposure Combined With Specific Exercise Training (BEST) Program in Patients With Cancer
Status: RECRUITING
Conditions: Lung Neoplasm|Esophageal Neoplasms
Interventions: BEHAVIORAL: Daylight exposure combine walking|BEHAVIORAL: Stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose-Confirmation, Immunogenicity and Safety Study of the Clostridium Difficile Vaccine Candidate VLA84 in Healthy Adults Aged 50 Years and Older. Phase II Study
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: BIOLOGICAL: VLA84|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pelvic Floor Rehabilitation Study (Beckenboden-Rehabilitationsstudie - BREST)
Status: COMPLETED
Conditions: Postpartum Urinary Incontinence
Interventions: DEVICE: Vaginal pessary|BEHAVIORAL: Standard care|PROCEDURE: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the DISC-OVARY Trial
Status: NOT_YET_RECRUITING
Conditions: BRCA Mutation|Estrogen Deficiency|Menopause Surgical|Menopause Related Conditions|Menopause, Premature|Ovary Cancer
Interventions: PROCEDURE: Theca and Granulosa Cell Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Niclosamide in Pediatric Patients With Relapsed and Refractory AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Niclosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Tinted Soft Scleral Eye Shields When IPL is Applied on Eyelids
Status: COMPLETED
Conditions: Dry Eye Disease|Meibomian Gland Dysfunction
Interventions: COMBINATION_PRODUCT: Protection of eyes with tinted soft scleral eye shields
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis
Status: COMPLETED
Conditions: Glucose Tolerance
Interventions: DRUG: Rifampicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of an Educational Program for Adults on Hemodialysis With Fatigue
Status: COMPLETED
Conditions: Renal Dialysis|Fatigue|Rehabilitation|Quality of Life|Kidney Diseases
Interventions: BEHAVIORAL: The "PEP" (Personal Energy Planning) Program|BEHAVIORAL: General Education about Kidney Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of PET Amyloid Imaging in Japanese and Western Subjects
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease|Healthy
Interventions: DRUG: [18F] Flutemetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalency Study of Divalproex Sodium DR Tablets, 500 mg of Dr.Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Divalproex Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Sensor for Biometrics During Locoregional Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Cancer of Head and Neck
Interventions: DEVICE: wearable sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Integrated Treatment in FND (Functional Neurological Disorders)
Status: RECRUITING
Conditions: Functional Neurological Disorder
Interventions: OTHER: Psychotherapy|BEHAVIORAL: Physiotherapy|OTHER: Non-Invasive Brain Stimulation (NIBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PNE Plus Exercise Versus Exercise for Chronic Rotator Cuff Tendinopathy
Status: SUSPENDED
Conditions: Rotator Cuff Tendinosis
Interventions: OTHER: Pain neuroscience education|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of ZR2 Versus R-CHOP-like Regimen for Elderly Patients With Newly Diagnosed Diffuse Large B Cell Lymphoma.
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Zanubrutinib+Rituximab+Lenalidomide|DRUG: RCHOP/RCDOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Left Stellate Ganglion Block In Out-of-hospital Cardiac Arrest Due to Refractory VEntricular Arrhythmias (LIVE Study)
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Ventricular Fibrillation Sustained
Interventions: PROCEDURE: PSGB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Subcutaneous and Intravenous ALXN1720 With and Without rHuPH20 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN1720 SC|DRUG: ALXN1720 IV|DRUG: rHuPH20|DRUG: Placebo SC|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: DRUG: TQ-B3525 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib in Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck
Status: UNKNOWN
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Apatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: OTHER: FMRI with sham controlled feedback|OTHER: FMRI with real time feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Indomethacin and Cardiac Bypass Surgery
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Indomethacin|DRUG: Acetaminophen & Indomethacin|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Circuit Training Combine With Square-Stepping Exercise, Strength Training and Balance Training on Senior Fitness and Fall Risk in Elderly in the Community
Status: RECRUITING
Conditions: Circuit-Based Exercise|Exercise Test|Community Health Nursing|Aged|Physical Fitness
Interventions: BEHAVIORAL: Circuit Training Combine with Square-Stepping Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Iocide Oral Rinse Against Gingival Inflammation
Status: UNKNOWN
Conditions: Gingivitis|Investigation of Biological Markers of Inflammation
Interventions: DRUG: Iocide Oral Rinse|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talazoparib and Axitinib for People With Previously Treated Advanced Kidney Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Cancer|Renal Cell Carcinoma|Unresectable Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: Talazoparib|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: MLN4924|DRUG: Fluconazole|DRUG: Itraconazole|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kochujang Pills on Blood Lipids Profiles in Hyperlipidemia Subjects
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Kochujang Pills|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Toripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Follicular Lymphoma Grade IIIb|Transformed Lymphoma|EBV-Positive DLBCL, Nos|ALK-Positive Anaplastic Large Cell Lymphoma
Interventions: DRUG: Toripalimab, Rituximab|DRUG: R-CHOP Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simulation Based Safety Mobilization Program on Patient Outcomes
Status: COMPLETED
Conditions: Patient Outcomes|Simulation Based Learning
Interventions: OTHER: Simulation based safety mobilization program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Application of Patented Lyophilized PLT in Acne Scar Repairment.
Status: COMPLETED
Conditions: Atrophic Acne Scar
Interventions: OTHER: PLT|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: S-531011|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Omeprazole 20mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing A Theory-Driven Self-Management Intervention for Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain
Interventions: DEVICE: Virtual Auricular Point Acupressure (APA)|OTHER: In-Person Training|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: All-Polyethylene Tibias in TKA: PS vs CS Implants
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Posterior stabilized all-polyethylene tibial component|DEVICE: Cruciate retaining all-polyethylene tibial component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab in Combination With Lenvatinib as Neoadjuvant Therapy in Resectable Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Toripalimab (JS001 )|DRUG: Toripalimab (JS001 ) Lenvatinib|DRUG: Toripalimab (JS001 ) Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Status: COMPLETED
Conditions: Autism|Asperger's Syndrome|Pervasive Developmental Disorder Not Otherwise Specified|Generalized Anxiety Disorder|Social Phobia|Separation Anxiety Disorder|Obsessive-compulsive Disorder|Specific Phobia
Interventions: OTHER: Cognitive Behavioral Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Assess Safety, Tolerability, PK and PD of AGMB-447 in Healthy Participants and Participants With IPF
Status: RECRUITING
Conditions: IPF
Interventions: DRUG: AGMB-447|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso
Status: COMPLETED
Conditions: Uncomplicated P. Falciparum Malaria in Children
Interventions: DRUG: Artesunate-amodiaquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes on the Interproximal Bone Level on Direct Prostheses or With Intermediate Abutments
Status: UNKNOWN
Conditions: Periimplant Bone Loss|Marginal Periimplant Bone Level|Periimplantitis
Interventions: DEVICE: prosthesis connected directly to the implants|DEVICE: Intermediate abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Interventions in Children With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Preschool Child
Interventions: DRUG: Methylphenidate|BEHAVIORAL: Parental training|OTHER: Psychoeducational groups for parents|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT