pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lubiprostone for Chronic Idiopathic Constipation Treatment
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Interleukin-2 in Treating Young Patients With Relapsed or Refractory Ewing's Sarcoma or Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma|Sarcoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous EBV-transformed B lymphoblastoid-tumor fusion cell vaccine|BIOLOGICAL: therapeutic autologous lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma
Status: UNKNOWN
Conditions: Malignant Glioma|Glioblastoma Multiforme|GBM|Anaplastic Astrocytoma|Oligo-Astrocytoma|Gliosarcoma
Interventions: DRUG: 131-I-TM-601|DRUG: 131I-TM601
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fit Physicians: Use of Activity Monitors and Activity Integration Program in First Year Medical Students
Status: COMPLETED
Conditions: Motor Activity|Body Weight Changes
Interventions: RADIATION: iDEXA Scan|OTHER: Wellness Lectures|OTHER: Exercise intervention|OTHER: Activity monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Intensivist Communication on Surrogate Prognosis Interpretation
Status: COMPLETED
Conditions: Critical Illness
Interventions: BEHAVIORAL: Indirect - other patients|BEHAVIORAL: Indirect - physiology|BEHAVIORAL: Redirection|BEHAVIORAL: Direct communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Crossover Study to Evaluate the Bioavailability of Ibrutinib Suspension and Sprinkle Formulations Compared to Capsules in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibrutinib (Treatment A) [Reference]|DRUG: Ibrutinib (Treatment B)|DRUG: Ibrutinib (Treatment C)|DRUG: Ibrutinib (Treatment D)|DRUG: Ibrutinib (Treatment E)|DRUG: Ibrutinib (Treatment F)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer
Status: RECRUITING
Conditions: Glottis Tumor|Larynx Cancer
Interventions: RADIATION: Single Vocal Cord Irradiation (SVCI)|PROCEDURE: Arm A: Transoral CO2-Laser Microsurgical Cordectomy (TLM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis
Status: COMPLETED
Conditions: Hepatitis B, Chronic|Cirrhosis|Fibrosis|Chronic Hepatitis B
Interventions: DRUG: adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients' Opinions and Responses to the National Cancer Institute's Colorectal Cancer Risk Assessment Tool
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Patient views NCI CRC RAT|BEHAVIORAL: View presentation regarding current chance of having an advanced adenoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of MK-4827 for the Treatment of Mantle Cell Lymphoma (MK-4827-002)
Status: WITHDRAWN
Conditions: Lymphoma|Mantle-Cell
Interventions: DRUG: MK-4827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax for Prevention of Differentiation Syndrom in Acute Promyelocytic Leukemia Patients
Status: ENROLLING_BY_INVITATION
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine in Modifying Immune Paralysis In Patient With Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment
Status: UNKNOWN
Conditions: Corneal Neovascularization
Interventions: DRUG: KDR2-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Directed Lifestyle Change and Health Promotion Program or Usual Care in Low-Income, Uninsured Participants in Los Angeles County, California
Status: COMPLETED
Conditions: Impoverished Population
Interventions: BEHAVIORAL: Self-Care Stimulating Disease Prevention Program (SCSDPP)|OTHER: Stand procedures, no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peer Support in Alcohol Dependence
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Quality life questionnaire AQoLS|BEHAVIORAL: Quality life questionnaire Euroqol EQ-5D-5L|OTHER: Peer support consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Polypill for Secondary Prevention of Ischemic Heart Disease
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|ST Elevation Myocardial Infarction|Non-ST Elevation Myocardial Infarction
Interventions: DRUG: Polypill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Enhanced Counseling Using Complementary Feeding Recommendation Based on Linear Programming on Nutritional Status,Omega-3 Fatty Acids, Malondialdehyde, and Alpha-Tocopherol in Overweight Children in East Jakarta
Status: COMPLETED
Conditions: Complementary Feeding Recommendation|Linear Programming,|Nutritional Status|Omega-3 Fatty Acids|Malondialdehyde|Alpha-Tocopherol|Overweight
Interventions: BEHAVIORAL: Enhanced Counseling using CFR based on Linear Programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brain/Neural Hand Exoskeleton Control for Restoration of Bimanual Tasks
Status: UNKNOWN
Conditions: Spinal Cord Injury|Stroke
Interventions: DEVICE: Brain/neural hand exoskeleton (B/NHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multisession Radiosurgery for Optic Nerve Sheath Meningiomas
Status: UNKNOWN
Conditions: Optic Nerve Sheath Tumors, Benign
Interventions: RADIATION: Multisession Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Cytokine Response During Exercise Dyspnea in Patients With Chronic Obstructive Pulmonary Disease (COPD). Effect of Body Composition
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Severe|Dyspnea
Interventions: DEVICE: Effective noninvasive ventilation|DEVICE: Sham noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Benralizumab in Patients With Eosinophilic Gastritis and/or Gastroenteritis (The HUDSON GI Study)
Status: COMPLETED
Conditions: Eosinophilic Gastritis|Eosinophilic Gastroenteritis
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 68Ga-HBED-PSMA PET/CT and Conventional Imaging in Occult Biological Relapse Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer Recurrent
Interventions: DIAGNOSTIC_TEST: 68Ga-HBED-CC-PSMA PET / CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)
Status: COMPLETED
Conditions: Actinic Keratosis|Natural Daylight Photodynamic Therapy
Interventions: DRUG: Aminolevulinic Acid|DRUG: Methyl 5-aminolevulinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: EP-101 via nebulizer (eFlow®) 25 ug|DRUG: EP-101 via nebulizer (eFlow®) 50 ug|DRUG: EP-101 via nebulizer (eFlow®) 100 ug|DRUG: Placebo EP-101|DRUG: Tiotropium bromide via (Spiriva® Handihaler®)|DRUG: Ipratropium bromide Inhalation Solution via Handihaler® DPI|DRUG: EP-101 via nebulizer (eFlow®) 200 ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopy vs. Computed Tomography for Diagnosis of Displacement and Instability of Acute Scaphoid Waist Fractures
Status: WITHDRAWN
Conditions: Acute Scaphoid Waist Fractures
Interventions: DEVICE: Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: DIETARY_SUPPLEMENT: Kroger low calorie orange juice beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology
Status: RECRUITING
Conditions: Central Nervous System Neoplasm|Leptomeningeal Neoplasm|Metastatic Malignant Neoplasm in the Brain|Primary Brain Neoplasm
Interventions: OTHER: Electronic Health Record Review|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation
Status: COMPLETED
Conditions: Abortion|Dilation and Evacuation|Hemorrhage|Blood Loss
Interventions: DRUG: intravenous oxytocin|DRUG: Intravenous Fluids and Electrolytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Medical Therapy Versus Advanced Medical Therapy Plus Bariatric Surgery for the Resolution of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: PROCEDURE: Gastric bypass|PROCEDURE: Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Floatation-REST in Methamphetamine Use Disorder: A Pilot Study
Status: RECRUITING
Conditions: Amphetamine-Type Substance Use Disorder
Interventions: DEVICE: Float Pool|DEVICE: Float Chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tenofovir DF on Bone Metabolism in Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Eye exam|PROCEDURE: Oral exam|PROCEDURE: CT scan|PROCEDURE: Neuropsychological testing|PROCEDURE: Electrocardiogram|PROCEDURE: Echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: RP-3500 in combination with Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: bortezomib|DRUG: mitoxantrone hydrochloride|DRUG: etoposide|DRUG: cytarabine|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between "Dong-A Atorvastatin Tab" and "Lipitor Tab"
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Lipitor 80mg Tab → Dong-A Atorvastatin 80mg Tab|DRUG: Dong-A Atorvastatin 80mg Tab → Lipitor 80mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil
Status: COMPLETED
Conditions: Hyperalgesia
Interventions: DRUG: Alfentanil|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Are the Pancreatic Serum Proteins Pancreatic Stone Protein (PSP) and Pancreatitis-Associated Protein (PAP) Predictive for the Development of Sepsis? Retrospective Study in Trauma Patients With Soft Tissue Defects.
Status: UNKNOWN
Conditions: Trauma Patients With Soft Tissue Defects
Interventions: PROCEDURE: retrospective Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Motexafin Gadolinium Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma
Status: COMPLETED
Conditions: Untreated Childhood Brain Stem Glioma
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sodium-glucose Co-transporter-2( SGLT-2 ) Inhibition on Sympathetic Nervous System Activity in Humans
Status: RECRUITING
Conditions: Metabolic Syndrome|Type 2 Diabetes Mellitus|Obesity
Interventions: DRUG: Empagliflozin Oral Tablet [Jardiance]|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Coracoclavicular Fixation With Versus Without Acromioclavicular Stabilization for Repair of Acute Acromioclavicular Joint Dislocations: A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Acromioclavicular Joint Dislocation
Interventions: PROCEDURE: Coracoclavicular fixation with acromioclavicular stabilization for the management of an unstable acromiclavicular luxation|PROCEDURE: Coracoclavicular fixation for the management of an unstable acromiclavicular luxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation and Hyperbaric Chamber for Women Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Hyperbaric group|OTHER: Magnetic group|OTHER: Physical group|OTHER: Baseline group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Neuroscience Education and Graded Exposure to Movement in Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Neoplasms|Pain, Chronic|Quality of Life
Interventions: OTHER: Online physiotherapy protocol based on pain neuroscience education and gradual exposure to movement.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NerveTrend vs. NerveAssure in Prevention of Recurrent Laryngeal Nerve Injury During Thyroid Surgery
Status: RECRUITING
Conditions: Thyroid Diseases|Surgery|Recurrent Laryngeal Nerve Injuries
Interventions: DEVICE: Neuromonitoring of the recurrent laryngeal nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
Status: RECRUITING
Conditions: Myelofibrosis|Primary Myelofibrosis|Post-PV MF|Post-ET Myelofibrosis
Interventions: DRUG: TL-895|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Placebo|DRUG: Veliparib|DRUG: Carboplatin|DRUG: Temozolomide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptive DDI Study
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: sotagliflozin|DRUG: oral contraceptive|DRUG: oral contraceptive + sotagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tesetaxel Plus Capecitabine and Cisplatin in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Carcinoma
Interventions: DRUG: Tesetaxel-capecitabine-cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .
Status: UNKNOWN
Conditions: Necrotic Pulp With Symptomatic Apical Periodontitis
Interventions: DRUG: Calcium hydroxide intracanal medication application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brief Mindfulness Intervention for Orthopedic Patients: Mechanistic Investigation
Status: SUSPENDED
Conditions: Pain
Interventions: BEHAVIORAL: Pain Coping Information|BEHAVIORAL: Mindful Pain Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Observational Study to Determine the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Locally Advanced Basal Cell Carcinoma (laBCC)
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: DRUG: Vismodegib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Fluzone Vaccine Administered by Intradermal Route in Comparison With Standard Fluzone® in Adults
Status: COMPLETED
Conditions: Orthomyxoviridae Infection|Influenza|Myxovirus Infection
Interventions: BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B|BIOLOGICAL: Influenza Virus Vaccine USP Trivalent Types A and B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: NKTR-255|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional Support Messages Following a Cancer Diagnosis
Status: COMPLETED
Conditions: Psychological Stress|Anxiety
Interventions: BEHAVIORAL: Questionnaire 1a|BEHAVIORAL: Questionnaire 1b|BEHAVIORAL: Questionnaire 2a|BEHAVIORAL: Questionnaire 2b|BEHAVIORAL: Questionnaire 3a|BEHAVIORAL: Questionnaire 3b|BEHAVIORAL: Questionnaire 4a|BEHAVIORAL: Questionnaire 4b
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes
Status: TERMINATED
Conditions: Mood|Memory Deficit
Interventions: DRUG: Memantine|DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Photon Emission Computed Tomography/Computed Tomography With Pentavalent 99mTc Dimercaptosuccinic Acid in Patients With Brain Glioma; Correlation With IDH Mutation
Status: NOT_YET_RECRUITING
Conditions: Brain Glioma
Interventions: RADIATION: SPECT with pentavalent 99mTc DMSA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency
Status: RECRUITING
Conditions: Aggressive Non-Hodgkin Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-Cell Lymphoma|Chronic Lymphocytic Leukemia|Diffuse Large B-Cell Lymphoma|Enteropathy-Associated T-Cell Lymphoma|Hepatosplenic T-Cell Lymphoma|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Mediastinal (Thymic) Large B-Cell Lymphoma|Nasal Type Extranodal NK/T-Cell Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Primary Cutaneous Anaplastic Large Cell Lymphoma|Refractory Anaplastic Large Cell Lymphoma|Small Lymphocytic Lymphoma|Subcutaneous Panniculitis-Like T-Cell Lymphoma
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Probiotic on Oral Microbiota and Glycemic Control in Type 2 Diabetics; A Randomized Clinical Trial
Status: COMPLETED
Conditions: Diabetes Mellitus,Type 2|Periodontitis
Interventions: DIETARY_SUPPLEMENT: Effects of an oral probiotic or placebo use on oral microbiota and glycemic index in Type 2 diabetic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Timing and Failure Prediction of High Flow Nasal Cannula Oxygen Therapy in Emergency Department: Prospective Observational Single Center Study
Status: NOT_YET_RECRUITING
Conditions: Respiratory Insufficiency|Acute Hypercapnic Respiratory Failure|Acute Hypoxemic Respiratory Failure|Hypercapnic Acute|Respiratory Failure|Hypercapnic Respiratory Failure|Hypoxemic Acute Respiratory Failure|Hypoxemic Respiratory Failure|Respiratory Depression|Ventilatory Depression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EEG Personalized Transcranial Magnetic Stimulation (eTMS) for Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: EEG-based personalized TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Recombinant Vaccinia Virus to Treat Metastatic Colorectal Carcinoma in Patients Undergoing Complete Resection of Liver Tumors
Status: TERMINATED
Conditions: Colorectal Carcinoma
Interventions: DRUG: Recombinant Vaccinia GM-CSF; RAC VAC GM-CSF (JX-594)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteral Nutrition in Cancer Patient
Status: COMPLETED
Conditions: Malnutrition|Cancer|Pediatric
Interventions: DIETARY_SUPPLEMENT: industrialized oral supplementation (IOS) and tube feeding regimen (TFR) with Nutren
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of DA-2803 in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Vemlidy Tab|DRUG: DA-2803 Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mixed Methods Study of Nutrition Practice in Cancer Care on Non-Hodgkin Lymphoma Population
Status: RECRUITING
Conditions: Lymphoma, B-Cell
Interventions: DIETARY_SUPPLEMENT: Short-Term Calorie Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis
Status: RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DEVICE: Alocross 0.2% Unit Dose|DEVICE: Vismed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction
Status: COMPLETED
Conditions: Moderate Hepatic Impairment|Severe Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of the Eastern Equine Encephalitis (EEE) Vaccine
Status: COMPLETED
Conditions: Eastern Equine Encephalitis
Interventions: BIOLOGICAL: Eastern Equine Encephalitis Vaccine, Inactivated, Dried, TSI-GSD 104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electrical Stimulation in Patients With Unipolar Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: PROCEDURE: Stimulation of the trigeminal nerve (active stimulation)|PROCEDURE: Placebo stimulation of the trigeminal nerve (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Oral Amoxicillin Versus Intravenous Ceftriaxone
Status: NOT_YET_RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Amoxicillin/CA|DRUG: IV ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Mentoring to Improve Self-management in Youth With IBD
Status: TERMINATED
Conditions: Pediatric Crohns Disease|Pediatric Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Group educational activities|BEHAVIORAL: IBD educational website|BEHAVIORAL: Monthly check-in calls from program coordinator|BEHAVIORAL: Mentor|BEHAVIORAL: Fun group activities|BEHAVIORAL: Parent support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine, With or Without Aura
Interventions: DRUG: Ubrogepant|DRUG: Placebo-matching Ubrogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts
Status: NOT_YET_RECRUITING
Conditions: Fatigue|Shift Work Type Circadian Rhythm Sleep Disorder
Interventions: BEHAVIORAL: Personalized coaching|BEHAVIORAL: Nutrition handout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study Of Ga-68-DOTA-TOC Imaging In Participants With Small Bowel Carcinoid Tumors
Status: WITHDRAWN
Conditions: Small Bowel Carcinoid Tumor
Interventions: DRUG: Ga-68-DOTA-TOC|DEVICE: Siemens PET/MR scanner|OTHER: Standard Siemens Software|DRUG: LAR Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kombucha Tea for Improving Defecation in Patients With Schizophrenia- a Randomized Controlled Study
Status: COMPLETED
Conditions: Schizophrenia|Constipation|Kombucha Tea
Interventions: DIETARY_SUPPLEMENT: Commercial Kombucha tea (Brand name E-Ben Organic Kombucha Lemon)|DIETARY_SUPPLEMENT: Lemon tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Opioid Pramipexole and Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Pramipexole Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Pain in Late Cold Water Immersion, Muscular Recruitment, Postural Control Dynamic and Sleep Quality
Status: COMPLETED
Conditions: Pain|Sleep
Interventions: OTHER: Cold water immersion, with 10 degrees, for 10 minutes|OTHER: immersion in water at room temperature|OTHER: active recovery - running|OTHER: rest in the chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saphenous Nerve Block for Partial Meniscectomy
Status: UNKNOWN
Conditions: Pain, Joint|Pain, Procedural|Meniscectomy
Interventions: PROCEDURE: Saphenous Nerve Block|DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen and Ibuprofen With and Without Magnesium and Primary Migraine in Childhood
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Magnesium 400Mg|DRUG: Ibuprofen 10 mg/kg|DRUG: acetaminophen 15 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen
Status: RECRUITING
Conditions: Constipation
Interventions: DRUG: PEG 3350|DRUG: PEG-3350 with electrolytes|DRUG: Glycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Hygiene Intervention Pilot Study
Status: COMPLETED
Conditions: Dental Caries|Gingivitis
Interventions: OTHER: oral health assessment|OTHER: Questionnaires|OTHER: Clinical Exam|OTHER: Microbiological sampling|OTHER: Monitoring Adherence|OTHER: Varnish application|OTHER: Consent|OTHER: Educational Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Ovotransferrin and Lactoferrin on Iron Absorption From Ferrous Sulfate in Adult Women
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: FeSO4 + OTf|DIETARY_SUPPLEMENT: FeSO4 + Lf|DIETARY_SUPPLEMENT: FeSO4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors
Status: TERMINATED
Conditions: Glioma|Pilocytic Astrocytoma|Anaplastic Astrocytoma|Glioblastoma|Mixed Oligoastrocytoma|Mixed Glioma|Oligodendroglioma|Optic Glioma|Astrocytoma
Interventions: DEVICE: MRI-guided laser ablation|DRUG: Doxorubicin|DRUG: Etoposide|DEVICE: Dynamic contrast-enhanced (DCE) MRI|DEVICE: Dynamic susceptibility contrast (DSC) MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Dry Needling and Tens in Chronic Neck Pain
Status: COMPLETED
Conditions: Myofascial Neck Pain
Interventions: OTHER: Dry Needling|OTHER: "TENS" and "dry needling"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Concurrent Controlled Trial to Assess the Safety and Effectiveness of the Separator 3D as a Component of the Penumbra System in the Revascularization of Large Vessel Occlusion in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke From Large Vessel Occlusion
Interventions: DEVICE: Penumbra System with Separator 3D|DEVICE: Penumbra System alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing in Physiotherapy for Patients With Low Back Pain
Status: COMPLETED
Conditions: Motivational Interviewing
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Anti-inflammatory Information
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of SUN N4057 in Subjects With Acute Ischemic Stroke and Measurable Penumbra on Magnetic Resonance Imaging (MRI)
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: piclozotan low dose|DRUG: placebo|DRUG: piclozotan high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolution of Vestibular Function After Treatment of a Vestibular Schwannoma by Gamma-knife Radio-surgery
Status: NOT_YET_RECRUITING
Conditions: Vestibular Schwannoma|Neurinoma, Acoustic|Acoustic Neuroma
Interventions: OTHER: Vestibular exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders
Status: COMPLETED
Conditions: Distracted Driving|Driving Impaired
Interventions: BEHAVIORAL: Free Phone Mounts|BEHAVIORAL: Commitment Contract|BEHAVIORAL: Personalized Habit Tips|BEHAVIORAL: Social Gamification Feedback|BEHAVIORAL: "Contest" Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heparin Binding Protein in Patients With Acute Respiratory Failure Treated With GCSF (Filgrastim)
Status: COMPLETED
Conditions: Acute Respiratory Failure|Critically Ill
Interventions: DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Offer of Nurse-Driven Screening for COVID-19 in Emergency Departments in the Paris Metropolitan Area, DEPIST-COVID
Status: COMPLETED
Conditions: SARS-CoV Infection|Nurse's Role
Interventions: PROCEDURE: Systematic offer of nurse-driven SARS-CoV-2 screening combined with usual practice|OTHER: Usual emergency department practice with physician-directed diagnostic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of CPP-ACP Paste on Dental Caries in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: 10 % w/v CPP-ACP paste|DRUG: the paste without CPP-ACP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wellness Interventions After Transplant Study
Status: COMPLETED
Conditions: Organ Transplant
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MSBR)|BEHAVIORAL: Health Education (HE)|BEHAVIORAL: Delayed Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Open-label Study to Assess Usability of the Medical Information Device #1 (MIND1) System in Adults With Schizophrenia On Oral Aripiprazole
Status: COMPLETED
Conditions: Schizophrenia|Mental Disorder|Nervous System Diseases
Interventions: DEVICE: MIND1 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: RADIATION: SMART|DRUG: PF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder|Sleep Disturbance
Interventions: BEHAVIORAL: Power Down manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Genital Neoplasms, Male|Urogenital Neoplasms|Neoplasms by Site|Neoplasms|Genital Diseases, Male|Prostatic Disease
Interventions: DRUG: 18F-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Alpha-Agonist|DRUG: α-adrenergic receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Fasting Following Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke|Intermittent Fasting
Interventions: DIETARY_SUPPLEMENT: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Transcatheter Arterial Chemoembolization (TACE) and Sorafenib for Patients With Unresectable Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: TACE (Transcatheter Arterial Chemoembolization )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: ATEMPT 2.0: Adjuvant T-DM1 vs TH
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: trastuzumab-emtansine|DRUG: Trastuzumab SC|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of a New CC-220 Capsule Formulation, Compared to a Reference CC-220 Capsule Formulation, in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CC-220
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX)
Status: COMPLETED
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: RNF|DRUG: RNF|DRUG: RNF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Different Cervical Anterior Discectomy Procedures by After Procedure Sagittal Alignment on Radiograph
Status: UNKNOWN
Conditions: Cervical Disc Degeneration
Interventions: PROCEDURE: ACD|PROCEDURE: ACDF|PROCEDURE: ACDA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Endostatin (EndostarTM) Injection in Treatment of Recurrent Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: EndostarTM Injection|DRUG: Gemcitabine|DRUG: Navelbine|DRUG: Platinum|DRUG: Xeloda Tablets:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Doxycycline hyclate (Doryx)|DRUG: Doxycycline hyclate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of CS12192 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CS12192 capsule|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: (Gastrografin Use in Small Bowel Obstruction Caused by Adherences)
Status: COMPLETED
Conditions: Adhesive Small Intestine Obstruction
Interventions: OTHER: traditional conservative treatment (TT)|DRUG: Gastrografin®: G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cognitive-behavior Therapy on Fear Responses to Body Symptoms in Patients With Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder With Agoraphobia|Panic Disorder Without Agoraphobia
Interventions: BEHAVIORAL: Cognitive-behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open Label, Pilot Investigation, to Assess the Safety and Efficacy of Transplantation of Macro-encapsulated Human Islets Within the Bioartificial Pancreas Beta-Air in Patients With Type 1 Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Long-standing Type 1 Diabetes Mellitus
Interventions: DEVICE: Beta-Air device for encapsulation of transplanted human islets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Suction Techniques For Endoscopic Ultrasound-Guided Fine-Needle Biopsy In Pancreatic Solid Lesions
Status: COMPLETED
Conditions: Pancreatic Solid Lesions
Interventions: DEVICE: Stylet slow-pull technique|DEVICE: Standard suction technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of Angongniuhuang Pill on Restoring Consciousness for Patients Who Have Suffered From a Stroke
Status: UNKNOWN
Conditions: Stroke|Acute Ischemic Stroke
Interventions: DRUG: Angongniuhuang Pill|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Optical Coherence Tomography in Upper Urinary Tract Urothelial Carcinoma
Status: COMPLETED
Conditions: Transitional Cell Carcinoma of Urinary Tract
Interventions: DEVICE: Optical Coherence Tomography|DEVICE: Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of REPEVAX® Given One Month After REVAXIS®
Status: COMPLETED
Conditions: Healthy Adult
Interventions: BIOLOGICAL: REPEVAX® after REVAXIS®|BIOLOGICAL: REPEVAX® after Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION