pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of the Safety and Effectiveness of Two New Malaria Vaccines
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63-MSP1 (lower dose) vaccine and MVA-MSP1 vaccine|BIOLOGICAL: AdCh63-MSP1 vaccine (higher dose) and MVA-MSP1 vaccine followed by challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treating PTSD in Patients With Borderline Personality Disorder
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Borderline Personality Disorder|Suicide|Self-Injurious Behavior
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: PTSD Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical DN as an Adjunct to Eccentric Exercise, Stretching + MT for Achilles Tendinopathy
Status: RECRUITING
Conditions: Achilles Tendinopathy
Interventions: OTHER: Electric dry needling and conventional PT|OTHER: Conventional PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Narrow Band Imaging in Diagnosis of Colorectal Polyps
Status: COMPLETED
Conditions: Colorectal Polyp|Colorectal Neoplasms
Interventions: DIAGNOSTIC_TEST: Near Focus NBI|DIAGNOSTIC_TEST: Standard Focus NBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of Intraarticular Sodium Hyaluronate (Hyalgan) After Proximal Tibial Osteotomy in Treatment of Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Sodium Hyaluronate (Hyalgan)|PROCEDURE: Osteotomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Robot-assisted Surgery and Laparoscopy-assisted Surgery in Patients With Mid or Low Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: robot-assisted surgery|PROCEDURE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sweetness Intensity of a Sucrose Solution on Blood Glucose Regulation and Energy Intake
Status: COMPLETED
Conditions: Blood Glucose, Low|Hunger
Interventions: DRUG: Lactisole|DRUG: Rebaudioside M|OTHER: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Musculoskeletal Effects of Bicarbonate
Status: COMPLETED
Conditions: Muscle Loss|Fractures|Osteoporosis, Age Related|Fall Injury
Interventions: DIETARY_SUPPLEMENT: potassium bicarbonate|DIETARY_SUPPLEMENT: potassium bicarbonate|OTHER: Inactive placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Circumferential Pulmonary Vein Ablation (CPVA) Versus Antiarrhythmic Drug Therapy in for Paroxysmal Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Circumferential Pulmonary Vein Ablation|DRUG: Antiarrhythmic Drug Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of FB1003 in Healthy Subject
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: FB1003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Coloured-light in Retinitis Pigmentosa.
Status: NOT_YET_RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DEVICE: Coloured-light torch|DEVICE: Different coloured-light torch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Multicenter Trial Comparing TVT With TVT-O for Treatment of Female Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Stress Incontinence
Interventions: PROCEDURE: TVT and TVT-O minimally invasive surgical procedures|PROCEDURE: Surgery for female stress urinary incontinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cereal-based Products Fortified With Legumes and Effects on Body Weight Management
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: cereal-legume snack|OTHER: cereal snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Operative Procedures vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial
Status: RECRUITING
Conditions: Pseudotumor Cerebri|Idiopathic Intracranial Hypertension (IIH)
Interventions: DEVICE: Dural Venous Sinus Stenting|DEVICE: Cerebrospinal Fluid Shunting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Immunogenicity of Sub-unit Adjuvanted Influenza Vaccine Administered to Elderly Subjects, Formulation 2010-2011
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Seasonal flu vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Central Neck Dissection in Patients With Clinical Node Negative Thyroid Cancer
Status: COMPLETED
Conditions: Stage I Papillary Thyroid Cancer|Stage II Papillary Thyroid Cancer|Stage III Papillary Thyroid Cancer
Interventions: PROCEDURE: Thyroidectomy|PROCEDURE: entral lymph node dissection (CLND)|OTHER: Quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Revlimid With Fludarabine-Rituximab for CLL/SLL
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iTBS in Bipolar I Depression
Status: COMPLETED
Conditions: Bipolar Depression|Bipolar I Disorder
Interventions: DEVICE: Magnus Transcranial Magnetic Neuromodulation System (MNS) with SAINT®(Stanford Accelerated Intelligent Neuromodulation Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Side of Embryo Biopsy Interfering Implantation Potential
Status: COMPLETED
Conditions: Preimplantation Diagnosis
Interventions: PROCEDURE: Vegetal Pole blastomer embryo|PROCEDURE: Animal Pole blastomer embryo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Therapeutic Effect of Sildenafil in Patients With Coronary Vasospasm
Status: WITHDRAWN
Conditions: Coronary Vasospasm
Interventions: DRUG: single dose Sildenafil|DRUG: Single dose placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib + Vinorelbine in Non Small Cell Lung Cancer (NSCLC) and Breast Cancer
Status: TERMINATED
Conditions: Metastatic Non Small Cell Lung Cancer|Metastatic Breast Cancer
Interventions: DRUG: Pazopanib|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitors Plus Chemoradiotherapy for Metastatic Nasopharyngeal Carcinoma: an Open-label Single-arm, Phase II Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma|PD-1 Inhibitors|Chemoradiotherapy
Interventions: DRUG: PD-1 inhibitors|RADIATION: chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma
Status: COMPLETED
Conditions: Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: LS11 (talaporfin sodium)|DEVICE: Light source (interstitial light emitting diodes)|PROCEDURE: Intraoperative placement of device in glioma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Triathlon - A New Total Knee Prosthesis System - RSA Triathlon Standard vs. Short Keel
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Triathlon Standard Keel|DEVICE: Triathlon Short Keel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Combination of gemigliptin/metformin HCl sustained release 50/1000mg|DRUG: Coadministration of gemigliptin 50mg and metformin HCl extended release 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Impact of Case Manager Intervention on the 3-year Psychotic Episode Recurrence Rate in Patients Aged 16 to 30 Years With a First Psychotic Episode.
Status: RECRUITING
Conditions: Psychotic Episode
Interventions: OTHER: Case management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Versus Leisure Group for Adolescents With Depression
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: BEHAVIORAL: Aerobic exercise in group|BEHAVIORAL: Leisure activities in group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Transcranial Direct Current Stimulation on Fatigability and Fatigue Induced by a Selective Attention Task
Status: WITHDRAWN
Conditions: Fatigue
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Primary Hyperlipidemia or Mixed Dyslipidemia At Risk Of Cardiovascular Events
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Bococizumab (PF-04950615; RN316)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study)
Status: COMPLETED
Conditions: Dyskinesia|Levodopa Induced Dyskinesia (LID)|Parkinson's Disease
Interventions: DRUG: ADS-5102|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea|Gastroesophageal Reflux
Interventions: DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carpal Tunnel Release Through Mini Transverse Approach
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Carpal Tunnel Release|Carpal Tunnel Surgery|Carpal Tunnel Transverse Approach|CTS
Interventions: PROCEDURE: Carpal tunnel release through Mini Transverse Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial Reload Open LAR Case Series
Status: TERMINATED
Conditions: Low Anterior Resection|Proctosigmoid Resection|Rectal Cancer
Interventions: DEVICE: Covidien Radial Reload Stapler with Tri-Staple Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small Coronary Artery Treated by TAXUS Liberté Registry in Japan
Status: UNKNOWN
Conditions: Stable Angina Pectoris|Unstable Angina Pectoris
Interventions: DEVICE: TAXUS Liberté paclitaxel-eluting coronary stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Chemotherapy and PD-1 Inhibitor Combination With Anti-angiogenesis to Treat Elderly Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Pemetrexed|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: dHealth Solution for Improving Parent Adherence to Behavioral Treatment for ADHD
Status: ENROLLING_BY_INVITATION
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: CaregiverAssist|BEHAVIORAL: Behavioral Parent Training (CLS Parent Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Platelet Lysate Eye Drops for the Treatment of Severe Chronic Ocular Graft-versus-host Disease
Status: UNKNOWN
Conditions: Ocular Graft-versus-host Disease
Interventions: BIOLOGICAL: Allogeneic platelet lysate eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases
Status: RECRUITING
Conditions: Epstein-Barr Virus (EBV)-Associated Diseases|EBV+ Lymphoproliferative Disease With Primary Immunodeficiency (EBV+ PID LPD)|EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (EBV+ AID LPD)|EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous System (EBV+ CNS PTLD)|EBV+ Post-transplant Lymphoproliferative Disease (EBV+ PTLD)|Solid Organ Transplant Complications|Lymphoproliferative Disorders|Allogeneic Hematopoietic Cell Transplant|Stem Cell Transplant Complications|EBV+ Sarcomas|Leiomyosarcoma
Interventions: BIOLOGICAL: Tabelecleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Fully Covered Irradiation Stent for the Palliation of Malignant Dysphagia
Status: UNKNOWN
Conditions: Malignant Dysphagia
Interventions: DEVICE: Fully covered irradiation stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Vardenafil in the Treatment of Male Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Trabecular Micro-Bypass Stent in Combination With Cataract Surgery in Open Angle Glaucoma Subjects.
Status: COMPLETED
Conditions: Open-Angle Glaucoma
Interventions: DEVICE: iStent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the Electronic Health Record to Guide Management of Newborn Weight Loss
Status: COMPLETED
Conditions: Breastfeeding|Breastfeeding, Exclusive|Morbidity;Perinatal|Feeding, Bottle
Interventions: OTHER: NEWT|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Yttrium Y 90 Ibritumomab Tiuxetan and Rituximab in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet on Perinatal Mood and Cognition
Status: ACTIVE_NOT_RECRUITING
Conditions: Mood|Mothers|Healthy
Interventions: DIETARY_SUPPLEMENT: Flavonoid-rich diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anethesia Efficacy on Teeth With MIH (Molar Incisor Hypomineralisation)
Status: COMPLETED
Conditions: Low-level-laser Theraphy|Anesthesia, Local|Molar Incisor Hypomineralization
Interventions: PROCEDURE: Photobiomodulation|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Therapeutic Dose 1|DRUG: Therapeutic Dose 2|DRUG: Supra-therapeutic Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Trout Fed With a Vegetable Based Feed on Cardiovascular Risk Markers and Plasma Proteome
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: Effects of trout on CVD risk markers and plasma proteome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Reliability of Synchronized Non-invasive Intermittent Positive Pressure Ventilation in Preterm Infants After Birth
Status: UNKNOWN
Conditions: Preterm Infant|Delivery Room|Respiratory Support|Synchronized Noninvasive Positive Pressure Ventilation (SNIPPV)
Interventions: OTHER: S-NIPPV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BASIC (Boric Acid, Alternate Solution for Intravaginal Colonization) Study
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: Placebo|DRUG: Boric acid|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transmuscular Quadratus Lumborum Block Plus Pericapsular Injection vs Pericapsular Injection
Status: COMPLETED
Conditions: Hip Pain Chronic
Interventions: PROCEDURE: Transmuscular Quadratus Lumborum Block|PROCEDURE: Pericapsular injection|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic|Diabetes Complications
Interventions: DRUG: MRE0094|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy Mechanism of Natural Psychotherapy for Neurosis
Status: UNKNOWN
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Natural Psychotherapy|BEHAVIORAL: Mental Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Cofetuzumab Pelidotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Anti-CD20 Antibody With Bortezomib for Relapsed Refractory Autoimmune Hemolytic Anemia
Status: COMPLETED
Conditions: Autoimmune Hemolytic Anemia|Autoimmune Hemolytic Anemia and Autoimmune Thrombocytopenia
Interventions: DRUG: combination of a single dose anti-CD20 antibody and bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immuno-Response to Primary Cryotherapy for the Treatment of Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: PROCEDURE: cryotherapy|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Stabilization in Post-VATS
Status: COMPLETED
Conditions: Lung Cancer|Pain, Postoperative
Interventions: DEVICE: Posthorax Thoraxbelt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medical Management of Sleep Disturbance During Opioid Tapering
Status: COMPLETED
Conditions: Opioid Dependence|Opioid Withdrawal|Sleep Disturbance
Interventions: DRUG: Placebo oral capsule|DRUG: Low Dose Suvorexant|DRUG: High Dose Suvorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Randomized Placebo Controlled Study of Quetiapine for the Treatment of Depression in Adolescents With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIF 1149 BS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis|MASH - Metabolic Dysfunction-Associated Steatohepatitis
Interventions: DRUG: Efruxifermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Deficit Disorder Medication Response Study
Status: COMPLETED
Conditions: ADHD - Inattentive Type|ADHD - Combined Type
Interventions: DRUG: OROS-Methylphenidate and placebo for inattentive type pts|DRUG: OROS-Methylphenidate and placebo for combined type pts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-AP and Doxorubicin In Treating Patients With Metastatic or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: triapine|DRUG: doxorubicin hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of resVida on Liver Fat Content
Status: COMPLETED
Conditions: Elevated Liver Fat Content and Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans
Status: COMPLETED
Conditions: Insulin Sensitivity|Obesity
Interventions: OTHER: Cold exposure|OTHER: Cold exposure plus propranolol|OTHER: Thermoneutral Conditions|OTHER: Cold water consumption|OTHER: Tepid water consumption|OTHER: Exercise|OTHER: Meal consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19
Status: TERMINATED
Conditions: Dysosmia|Anosmia|Covid19
Interventions: OTHER: Smell Retraining|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COlonic Salvage by Therapeutic Appendectomy.
Status: UNKNOWN
Conditions: Colitis, Ulcerative
Interventions: PROCEDURE: Laparoscopic appendectomy|PROCEDURE: Endoscopic appendix biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech
Status: COMPLETED
Conditions: Apraxia of Speech|Aphasia|Cerebrovascular Accident
Interventions: BEHAVIORAL: Normal Auditory Feedback|BEHAVIORAL: Masked Auditory Feedback|BEHAVIORAL: Altered Auditory Feedback
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Geko Neuromuscular Stimulator vs Thromboembolism Deterrent Stockings (TEDS): DVT Prevention Study
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DEVICE: geko™ post-surgery for 48hrs then 4hrs/day until discharge.|DEVICE: TEDS post-surgery for 48hrs then 4hrs/day until discharge.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity|Executive Function Disorder
Interventions: DRUG: Concerta|DEVICE: Digital therapeutics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety, Tolerability and Biological Effects of REGN4461 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN4461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy
Status: COMPLETED
Conditions: Recurrent Aggressive Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Malignant Neoplasm|Recurrent Plasma Cell Myeloma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Refractory Aggressive Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Malignant Neoplasm|Refractory Plasma Cell Myeloma|Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma
Interventions: DRUG: Fluorine F 18-fluoroazomycin Arabinoside|PROCEDURE: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anterior Vaginal Wall Repair With Mesh in Combination With TVT-O to Reduce Urinary Stress Incontinence
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Preventive transobturator tension free vaginal tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Sciatic Nerve Block in Below Knee Amputation Surgery
Status: COMPLETED
Conditions: Sciatic Nerve Block
Interventions: PROCEDURE: sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: From Prevention to Treatment: How Biological Rhythms Can Maintain Perinatal Mental Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Postpartum|Anxiety State
Interventions: DEVICE: Blue Light Therapy|DEVICE: ControlLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: NPH insulin plus Complete Insulin Orders|DRUG: Complete Insulin Orders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis, Mucocutaneous
Interventions: BIOLOGICAL: Leish-111f + MPL-SE vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Stellate Ganglion Injection to Provide Relief From Hot Flushes
Status: COMPLETED
Conditions: Hot Flashes|Menopause
Interventions: PROCEDURE: Sympathetic nerve block with 1% lidocaine 1-2 ml|PROCEDURE: Superficial subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SIM0237 Alone or in Combination With BCG in NMIBC
Status: RECRUITING
Conditions: Non-Muscle-Invasive Bladder Cancer (NMIBC)
Interventions: DRUG: SIM0237|DRUG: SIM0237 and BCG|DRUG: SIM0237|DRUG: SIM0237 and BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Sphenoid Septation in MRI Compared With CT and Intraoperative Findings During Endoscopic Pituitary Adenoma Surgery
Status: COMPLETED
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: comparison of data from MRI with data from CT compared with intraoperative data from endoscopic pituitary adenoma surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
Status: COMPLETED
Conditions: Anesthetic Gas Consumption and Cost-Effectiveness
Interventions: DEVICE: ICU certified ventilator|DEVICE: Non-ICU certified ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of ATX01 in Adult Patients With CIPN (Chemotherapy-induced Peripheral Neuropathy)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: ATX01 10%|DRUG: ATX01 15%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Food Allergy Superheroes Training (FAST) Program
Status: COMPLETED
Conditions: Allergy;Food|Adherence, Treatment|Child, Only
Interventions: BEHAVIORAL: Food Allergy Superheroes Training (FAST) Program|OTHER: Food Allergy Knowledge Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Patients With Advanced Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumor|Cancer
Interventions: DRUG: AZD6244
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Study of SGN-00101 in Treating Pediatric Patients With Recurrent Respiratory Papillomatosis
Status: COMPLETED
Conditions: Papilloma|Recurrent Respiratory Papillomatosis
Interventions: DRUG: SGN-00101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Covered Stents to Treat Hemodialysis Access Stenoses in the Cephalic Arch and Central Veins
Status: TERMINATED
Conditions: Renal Failure
Interventions: DEVICE: GORE VIABAHN® Endoprosthesis with Heparin Bioactive Surface|PROCEDURE: PTA alone without use of the GORE VIABAHN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Persistence Study in Healthy Adults Previously Vaccinated With Twinrix Adult
Status: COMPLETED
Conditions: Hepatitis A|Hepatitis B
Interventions: PROCEDURE: Blood sampling|BIOLOGICAL: Engerix-B|BIOLOGICAL: Havrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Venglustat|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period
Status: RECRUITING
Conditions: Uncomplicated Symptomatic Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Limosilactobacillus reuteri 3613|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extracorporeal Shockwave Therapy on Ultrasonographic Changes in de Quervain Tenosynovitis
Status: NOT_YET_RECRUITING
Conditions: De Quervain Disease
Interventions: OTHER: Extracorporeal Shockwave therapy|OTHER: Traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: EUR-1008 (APT-1008)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Anticoagulant Adverse Reaction|Stroke|Major Adverse Cardiac Events
Interventions: DRUG: low-dose rivaroxaban|DRUG: Standard-dose rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Adrenal Insufficiency
Interventions: DIAGNOSTIC_TEST: Cosyntropin stimulation test|DIAGNOSTIC_TEST: Baseline blood tests|DEVICE: 30-hour ambulatory sampling of intestinal fluid|OTHER: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutation
Status: COMPLETED
Conditions: Locally Advanced or Metastatic NSCLC
Interventions: DRUG: Osimertinib 80 MG [Tagrisso]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on Cardiac Function in Hyperinflated COPD Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Olodaterol-Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Clinical Study to Evaluate COVID-19 Symptoms in "Long Hauler" Patients Who Participated in K031-120 or K032-120
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: KB109 + Self Supportive Care|OTHER: Self Supportive Care (SSC) Alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance of Restorative Materials in Primary Teeth
Status: NOT_YET_RECRUITING
Conditions: Caries; Dentin|Dental Caries
Interventions: DEVICE: Compomer|DEVICE: RMGIC|DEVICE: Giomer|DEVICE: Amalgam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Octenisept® in Patients With Chronic Wounds
Status: TERMINATED
Conditions: Ulcus Cruris
Interventions: DRUG: octenisept®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enalapril Maleate and Doxorubicin Hydrochloride in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: enalapril maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study Evaluating the Effectiveness of Omega Q Plus® Resveratrol at Increasing Blood Levels of CoQ10
Status: COMPLETED
Conditions: CoQ10 Blood Levels|CoQ10 Blood Levels With Statin Use
Interventions: DIETARY_SUPPLEMENT: Omega Q Plus Resveratrol (with 50mg CoQ10)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Low Back Pain
Status: TERMINATED
Conditions: Back Pain Lower Back Chronic
Interventions: DRUG: Buprenorphine|DRUG: Buprenorphine|DRUG: Oxycodone Immediate-Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovation of Audio-Visual Triage System in Combating the Spread of COVID-19 Infection and Its Efficacy: A Novel Strategy
Status: COMPLETED
Conditions: Audio-Visual Triage System|Anxiety Levels|COVID-19 Spread|GAD-7 Score|Healthcare Professionals|Screening Strategy
Interventions: DEVICE: Audio-Visual Triage System (AVT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Resolution Imaging of Retinal Vessels as a Biomarker of Cardiovascular Disease in Patients With Renal Insufficiency - RI
Status: UNKNOWN
Conditions: Retinal Imaging|Cardiovascular Biomarker|Renal Insufficiency
Interventions: DIAGNOSTIC_TEST: wall-to-lumen ratio measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Restylane Treatment Algorithm Approach for Participants With Appearance of Insufficient Bone Structure in the Lower Face Alone or in Combination With Facial Soft Tissue Deficiencies
Status: ACTIVE_NOT_RECRUITING
Conditions: Chin Augmentation
Interventions: DEVICE: Restylane Shaype|DEVICE: Restylane Defyne|DEVICE: Restylane Lyft lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telematics Device for Daily Monitoring of Vital Signs in Cancer
Status: RECRUITING
Conditions: Cancer|Cardiovascular Diseases|Respiratory Disease
Interventions: DEVICE: ButterfLife|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Unilateral Transversus Abdominis Plane Block in Pediatrics
Status: COMPLETED
Conditions: Unilateral TAP Block in Pediatric Patients Undergoing Lower Abdominal Surgery
Interventions: DRUG: Bupivacain|DRUG: Dexmedetomidine o.5 μg|DRUG: Dexmedetomidine 1 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Mefenamic Acid and Dexketoprofen on Postoperative Wisdom Dental Surgery
Status: COMPLETED
Conditions: Tooth, Impacted|Tooth Diseases
Interventions: PROCEDURE: Surgery of impacted mandibular wisdom teeth|PROCEDURE: Surgery of impacted mandibular wisdom teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Head Start Classroom-based Approaches and Resources for Emotion and Social Skill Promotion (Head Start CARES)
Status: COMPLETED
Conditions: Teacher Practice|Child Social-Emotional Development
Interventions: BEHAVIORAL: Incredible Years Teacher Training|BEHAVIORAL: Preschool PATHS|BEHAVIORAL: Tools of the Mind
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: First Safety Study in Humans of a Single Dose of CPG 52364
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo Comparator: Cohort 1 Placebo|DRUG: 52364 3 mg|DRUG: Placebo Comparator: Cohorts 2, 3, 4 & 5 Two subjects each arm will be assigned to receive placebo|DRUG: 52364 10 mg|DRUG: 52364 30 mg|DRUG: 52364 100 mg|DRUG: 52364 1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Vaccination With Peptides in Combination With Either Ipilimumab or Vemurafenib for the Treatment of Unresectable Stage III or IV Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma With Metastasis
Interventions: BIOLOGICAL: Vaccine consisting of a peptide derived from the protein IDO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Medulloblastoma|Central Nervous System Embryonal Tumors
Interventions: DRUG: Induction|DRUG: Single Cycle Intensive Chemotherapy|DRUG: Tandem 3 Cycle Intensive Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Stress Management Training on Perceiving and Coping With Stress and Developing Resilience
Status: COMPLETED
Conditions: Stress Management|Perceived Stress|Coping Strategy|Psychological Resilience
Interventions: BEHAVIORAL: Stress management training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Plerixafor Plus G-CSF to Mobilize and Collect 5×10^6CD34+ Cells/kg in Non-Hodgkin's Lymphoma (NHL) Patients for Autologous Transplantation
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Granulocyte-colony stimulating factor (G-CSF)|DRUG: Plerixafor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep vs Moderate Block: Impact on Operating Conditions & Patient Satisfaction
Status: WITHDRAWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Deep neuromuscular blockade|DRUG: Moderate neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Educational Website for Women With Ovarian Cancer & Caregivers
Status: COMPLETED
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Recurrent Ovarian Cancer|Fallopian Tube Cancer
Interventions: BEHAVIORAL: Usual Care Educational Website|BEHAVIORAL: Prototype System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cochlear Electrical Impedance and the Effect of Topical Dexamethasone on Cochlear Implant Surgery
Status: UNKNOWN
Conditions: Sensorineural Hearing Loss|Cochlear Implant
Interventions: DRUG: Dexamethasone|DRUG: Sterile isotonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT