pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Subcutaneously CM310/Placebo in Patients With Moderate-to-Severe Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Moderate-to-severe Atopic Dermatitis
Interventions: BIOLOGICAL: CM310|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players
Status: COMPLETED
Conditions: Chronic Pain Due to Injury|Acute Pain|Depression|Brain Injuries
Interventions: BEHAVIORAL: Experimental: Investigate the effects of an exercise intervention on retired APF players
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Cosmetic Product "Onco-Repair" on Grade 2 Hand Foot Syndrome
Status: COMPLETED
Conditions: Grade 2 Hand-foot Syndrom
Interventions: OTHER: Onco-Repair/ Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Clinical Trial of Nepicastat for Post Traumatic Stress Disorder (PTSD)
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder (PTSD)
Interventions: DRUG: SYN117 (nepicastat)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: RADIATION: Total Lymphoid Irradiation|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Thiotepa|DRUG: Melphalan|BIOLOGICAL: HPC,A Infusion|BIOLOGICAL: TC-NK Infusion|BIOLOGICAL: G-CSF|DRUG: Mesna|DEVICE: CliniMACS|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Daily Dosing With Levalbuterol, Racemic Albuterol, and Placebo in Pediatric Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: levalbuterol 90 mcg|DRUG: levalbuterol 180 mcg|DRUG: racemic albuterol 180 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery
Status: COMPLETED
Conditions: Mechanical Ventilation|Hospital Length of Stay|Minimally Invasive Cardiac Surgery
Interventions: DRUG: Dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Baricitinib in the Treatment of New-onset Juvenile Dermatomyositis (MYOCIT)
Status: RECRUITING
Conditions: Juvenile Dermatomyositis
Interventions: DRUG: Baricitinib|BIOLOGICAL: pharmacokinetics study|BIOLOGICAL: dosage of cytokines|BIOLOGICAL: transcriptomic analysis|BEHAVIORAL: Parent version of the Child Health Questionnaire (CHQ)|BEHAVIORAL: Childhood Health Assessment Questionnaire|BIOLOGICAL: Pregnancy test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Ketamine-lidocaine Versus Ketamine-fentanyl for Induction on the Hemodynamic Effects in Patients With Coronary Artery Disease
Status: RECRUITING
Conditions: Induction of General Anesthesia
Interventions: DRUG: Fentanyl|DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pre-existing Factors, Early Detection and Early Treatment of Breast Cancer Related Lymphedema
Status: UNKNOWN
Conditions: Lymphedema of Upper Arm|Breast Cancer|Diagnoses Disease
Interventions: DEVICE: compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bortezomib Plus GDP in the Treatment of Refractory and Relapsed Non-GCB DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Immune Response of Three Different Lots of an Influenza Vaccine Made by a New Manufacturing Process With a Vaccine Made by the Traditional Manufacturing Process for Season 2004/2005
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vero Cell-derived Influenza Vaccine|BIOLOGICAL: Egg cell-derived Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics Study of amlodipine10mg and candesartan32mg
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Candesartan32mg|DRUG: Amlodipine10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Axicabtagene Ciloleucel and Glofitamab as Second-Line Therapy for Relapsed or Refractory Patients With Large B Cell Lymphoma
Status: RECRUITING
Conditions: B Cell Lymphoma
Interventions: DRUG: Glofitamab|DRUG: Obinutuzumab|DRUG: Axi-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Range Finding Study With rBet v1-FV - in Adult Patients With Birch Pollen-Allergic Seasonal Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Placebo|BIOLOGICAL: rBet v1-FV|BIOLOGICAL: rBet v1-FV|BIOLOGICAL: rBet v1-FV|BIOLOGICAL: rBet v1-FV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Purple Rice on Glucose Tolerance, Serum Lipids and Inflammation
Status: COMPLETED
Conditions: Type 2 Diabetic
Interventions: DIETARY_SUPPLEMENT: Purple Rice|DIETARY_SUPPLEMENT: Brown Rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Results From Objective Brushing Data Saved From a Powered Toothbrush Related to Values for Oral Health
Status: COMPLETED
Conditions: Gingivitis|Periodontal Diseases
Interventions: DEVICE: Powered toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Repeat Dose Study to Investigate the Interaction of GSK2190915 on the Pharmacokinetics of Rosuvastatin
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Rosuvastatin 10 mg|DRUG: GSK2190915 30mg|DRUG: GSK2190915 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Albumin-paclitaxel Combined With Apatinib and Camrelizumab in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Albumin-paclitaxel, Apatinib, Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of BIBW 2992 (Afatinib) + Cetuximab in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Cetuximab|DRUG: Cetuximab|DRUG: BIBW 2992|DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Safety, Tolerability, and Efficacy Study of PD 0360324 in Chronic Pulmonary Sarcoidosis
Status: TERMINATED
Conditions: Pulmonary Sarcoidosis
Interventions: BIOLOGICAL: PD 0360324|OTHER: Normal Saline for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intensive Insulin Glulisine Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Basal Insulin and Oral Glucose-lowering Drugs
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE|DRUG: INSULIN GLULISINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resolvin D1 in Psoriasis Before and After Narrowband UVB Phototherapy
Status: UNKNOWN
Conditions: Psoriasis
Interventions: OTHER: skin biopsy before and after NB-UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Resectable Pancreatic Cancer|Borderline Resectable Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma
Interventions: DRUG: mFOLFIRINOX|DRUG: 5-Fluorouracil (5-FU)|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: NIS793|RADIATION: Chemoradiation|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sanofi Pasteur and Lanzhou Institute's Meningococcal (Group A and C) Polysaccharide Vaccine in Children
Status: COMPLETED
Conditions: Meningococcal Disease|Meningitis
Interventions: BIOLOGICAL: Meningococcal (Groups A and C) Polysaccharide Vaccine|BIOLOGICAL: Meningococcal (Groups A and C) Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects and Cost-Effectiveness of an Integrated Multidisciplinary Approach for Psychogeriatric Patients
Status: COMPLETED
Conditions: Delirium, Dementia, Amnestic, Cognitive Disorders|Memory Disorders
Interventions: PROCEDURE: DOC-PG: integrated multidisciplinary assessment|PROCEDURE: Usual care: assessment by GP or one of the regional services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Maternal Voice and Music Therapy on Pain and Physiological Parameters During in Intubated Children
Status: NOT_YET_RECRUITING
Conditions: Music Therapy|Pain|Physiological Parameters|Mother's Voice
Interventions: OTHER: Music Therapy|OTHER: Maternal Voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Covid-19 Outpatient Symptom Montelukast Oximetry Trial
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Montelukast 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renaparin® in Kidney Transplantation
Status: COMPLETED
Conditions: Delayed Graft Function
Interventions: DRUG: Renaparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty
Status: COMPLETED
Conditions: Anemia, Iron-Deficiency|Weight Loss
Interventions: DRUG: Intravenous Iron sucrose|DRUG: Oral Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain
Status: UNKNOWN
Conditions: Neuropathic Pain|HIV Neuropathy|HIV/AIDS|Pain
Interventions: OTHER: Standard Acupuncture / Moxibustion|OTHER: Individualized (Tailored) Active Acupuncture / Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults
Status: RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Flu Pandemic mRNA_Dose level 1|BIOLOGICAL: Flu Pandemic mRNA_Dose level 2|BIOLOGICAL: Flu Pandemic mRNA_ Dose level 3.|BIOLOGICAL: Flu Pandemic mRNA_ Dose level 4|BIOLOGICAL: Flu Pandemic mRNA_Dose level 5|BIOLOGICAL: Flu Pandemic mRNA_Dose level 6|BIOLOGICAL: Flu Pandemic mRNA_Dose level 7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study for Transfusionally Iron Overloaded Children, Adolescents and Adults Using FBS0701 (SSP-004184)
Status: TERMINATED
Conditions: Iron Overload Due to Repeated Red Blood Cell Transfusions
Interventions: DRUG: SSP-004184AQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of LNP-nCOV saRNA-02 Vaccine Against SARS-CoV-2, the Causative Agent of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: LNP-nCOV saRNA-02 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: nCD64 vs. Neutrophil/Lymphocyte Ratio for Predicting In-hospital Outcome in AE-COPD
Status: COMPLETED
Conditions: COPD Exacerbation|Copd
Interventions: DIAGNOSTIC_TEST: nCD64|DIAGNOSTIC_TEST: Neutrophil/Lymphocyte Ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Donanemab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EINSTEIN Junior Phase II: Oral Rivaroxaban in Young Children With Venous Thrombosis
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of BOL-DP-o-08 in Patients With Endometriosis Syndrome.
Status: WITHDRAWN
Conditions: Endometriosis
Interventions: DRUG: BOL-DP-o-08|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia
Status: COMPLETED
Conditions: Myocardial Ischemia|Physical Exercise
Interventions: OTHER: Maintenance of physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound vs. Auscultation for Optimal Depth of the Cuffless RAE Tube
Status: WITHDRAWN
Conditions: Intubation Complication|Child|Ultrasonography
Interventions: BEHAVIORAL: Ultrasound-guided determination of cuffless RAE tube depth|BEHAVIORAL: Auscultation-guided determination of cuffless RAE tube depth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Augmenting Effects of L-DOPS With Carbidopa and Entacapone
Status: TERMINATED
Conditions: Parkinson Disease|Multiple System Atrophy|Autonomic Nervous System Diseases
Interventions: DRUG: Droxidopa|DRUG: Carbidopa|DRUG: Entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of rTMS in Healthy Persons
Status: WITHDRAWN
Conditions: Executive Dysfunction|Pain|Mood
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Alvimopan in Major Spine Surgery
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Male Volunteers to Investigate Different Doses of a New Drug for the Treatment of Metabolic Diseases
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: SRT3025|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of DIRECT Transfer to ANGIOsuite on Functional Outcome in Severe Acute Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: direct angio-suite admission|PROCEDURE: standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial and Brain Natriuretic Peptide Secretion After Percutaneous Closure of the Left Atrial Appendage
Status: UNKNOWN
Conditions: Atrial Fibrillation|Stroke Prevention|Left Atrial Appendage
Interventions: DEVICE: WATCHMAN LAA system (Percutaneous left atrial appendage closure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer
Status: TERMINATED
Conditions: Kidney Neoplasms
Interventions: DRUG: IL-2 (interleukin-2)|DRUG: OKT3|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate in Combination With Tildrakizumab
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Tildrakizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Controlled Trial Comparing a Conservative Management and Laser Surgery
Status: COMPLETED
Conditions: Blood and Blood Disorders|Anemia, Neonatal|Hematologic Disease|Infant, Newborn, Diseases
Interventions: PROCEDURE: Fetoscopic laser surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder
Status: TERMINATED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Sertraline|DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin|DRUG: Metformin|DRUG: BCWP_C003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individual Dosing of Levothyroxine After Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Neoplasms|Hypothyroidism|Surgery
Interventions: DRUG: Levothyroxine Sodium Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychometric Validation of the "Antillanisée" Version of the Mini Mental State Examination (MMSEa)
Status: TERMINATED
Conditions: Elderly Patients|Cognitive Disorder|Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: "Antillanisée" Mini Mental State Examination (MMSEa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Identification of Non-responders to Levothyroxine Therapy
Status: COMPLETED
Conditions: Hypothyroidism|Biomarkers|Endocrine System Diseases
Interventions: DRUG: Levothyroxin|DRUG: Liothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone as Adjuvant to Bupivacaine in Suprazygomatic Maxillary Nerve Block
Status: NOT_YET_RECRUITING
Conditions: Nerve Block
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Strontium Chloride Associated With Photobiomodulation in the Control of Post-bleaching Sensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: PLACEBO (Negative Control)|OTHER: FBM|OTHER: ESTRÔNCIO|OTHER: FBM+ESTRÔNCIO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Major Outcomes in Elderly Patients With Self-Management of Oral Anticoagulation (SPOG60+)
Status: COMPLETED
Conditions: Long-Term Oral Anticoagulated Patients
Interventions: BEHAVIORAL: educational program for the self-management of OAC|BEHAVIORAL: 1 hour education - afterwards physician leaded OAC control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Two Week Cumulative Extrinsic Stain Removal of a Battery-powered Toothbrush and a Manual Toothbrush
Status: COMPLETED
Conditions: Dental Devices, Home Care
Interventions: DEVICE: Battery operated toothbrush|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brimonidine Tartrate for the Treatment of Injection Related Erythema
Status: WITHDRAWN
Conditions: Relapsing-Remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: peginterferon beta-1a|DRUG: brimonidine tartrate|DRUG: Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Interval Physical Training on Expiratory Flow Limitation in Recent Myocardial Infarction
Status: WITHDRAWN
Conditions: Expiratory Flow Limitation|Recent Myocardial Infarction
Interventions: OTHER: Interval Training (IT)|OTHER: Inspiratory Muscle Training (IMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bronchoprovocation Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CSJ117 in Adult Subjects With Mild Atopic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CSJ117|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of 4 Doses of MenACWY Conjugate Vaccine, Administered Concomitantly With Routine Vaccines, Among Infants Aged 2 Months
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: DTaP-IPV/Hib|BIOLOGICAL: HBV|BIOLOGICAL: PCV|BIOLOGICAL: MMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Minocycline Augmentation to Clozapine
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma
Status: RECRUITING
Conditions: Sarcoma
Interventions: DRUG: Talimogene Laherparepvec 100000000 PFU/1 ML Injection Suspension [IMLYGIC]|DRUG: Nivolumab IV Soln 100 MG/10ML|DRUG: Trabectedin 0.25 MG/1 VIAL Intravenous Powder for Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-workout Supplementation and Basketball
Status: ACTIVE_NOT_RECRUITING
Conditions: Sport Performance
Interventions: DIETARY_SUPPLEMENT: Multi-ingredient dietary supplement (caffeine, creatine monohydrate, β-alanine, citrulline malate, BCAA)|DIETARY_SUPPLEMENT: Placebo dietary supplement (97% maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: OA-PCP Intervention|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: acalabrutinib|DRUG: rituximab (IV)|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ossium Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in the Setting of Crohn's Disease
Status: RECRUITING
Conditions: Pouch, Ileal|Fistula
Interventions: DRUG: Ossium vBM-MSC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Narcolepsy Type 1
Status: COMPLETED
Conditions: Narcolepsy Type 1|Fmri
Interventions: DEVICE: transcutaneous auricular vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Marizomib + Panobinostat for Children With DIPG
Status: TERMINATED
Conditions: Diffuse Intrinsic Pontine Glioma|Pediatric Brainstem Glioma|Pediatric Brainstem Gliosarcoma, Recurrent|Pediatric Cancer|Pediatric Brain Tumor|Diffuse Glioma
Interventions: DRUG: Marizomib|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: RADIATION: 225^Ac-PSMA-617|RADIATION: 68^Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Cardiogram Evaluate the Prognosis of Percutaneous Revascularization of Chronic Total Occlusions
Status: UNKNOWN
Conditions: Coronary Chronic Total Occlusion
Interventions: DEVICE: stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Electronic Cigarettes on Lung Biology
Status: TERMINATED
Conditions: Lung Disease|Lung Disorder
Interventions: OTHER: Group A|OTHER: Group B|OTHER: Group C|OTHER: Group D|OTHER: Group E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Autistic Disorders Spectrum|Electroencephalography|Machine Learning
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Efficiency of the Left Ventricle in Asymptomatic Patients With Aortic Valve Stenosis - a Prognostic Marker and a Target for Intervention?
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: DRUG: Metoprololsuccinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mitomycin C, Irinotecan, and Cetuximab
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: Mitomycin C|DRUG: Cetuximab|DRUG: Irinotecan.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Does Neuromuscular Electrical Stimulation Benefit the Functional Ability of Elderly Patients With Chronic Obstructive Lung Disease
Status: COMPLETED
Conditions: Pulmonary Rehabilitation|Chronic Obstructive Lung Disease|Neuromuscular Electrical Stimulation|Pulmonary Function (FEV1/FVC)
Interventions: OTHER: Study Group chest physiotherapy program combined with neuromuscular electrical stimulation (NMES)|OTHER: Control Group Chest physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Macitentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Fermented Dairy Drinks on Intestinal Immune Response
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 1- Dairy drink containing probiotics A|DIETARY_SUPPLEMENT: 2- Dairy drink containing probiotics B|DIETARY_SUPPLEMENT: 3- Dairy drink without probiotics (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Effects of Motor Imagery and Mirror Therapy Versus Motor Relearning Program in Subacute Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: MOTOR IMAGERY+MIRROR THERAPY+ROUTINE PHYSICAL THERAPY|OTHER: MOTOR RELEARNING PROGRAM+ROUTINE PHYSICAL THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging
Status: RECRUITING
Conditions: Histiocytosis
Interventions: DRUG: fluorodeoxyglucose (18F-FDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)
Status: COMPLETED
Conditions: MSI Positive Colorectal Cancer|MSI Negative Colorectal Cancer|MSI Positive Non-Colorectal Cancers
Interventions: DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for Oral Mucositis and Functional Impairments During Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematologic Cancer
Interventions: DEVICE: Photobiomodulation|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: enzalutamide|DRUG: bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder
Status: COMPLETED
Conditions: Sleep-Related Eating Disorder
Interventions: DRUG: Topiramate or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Challenge Study in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High Titre Influenza virus|BIOLOGICAL: Medium - High Influenza virus|BIOLOGICAL: Medium Low Titre Influenza virus|BIOLOGICAL: Low titre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Repeat Influenza Vaccination Constrain Influenza Immune Responses and Protection
Status: RECRUITING
Conditions: Influenza, Human|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Influenza vaccination: Fluarix Tetra, Vaxigrip Tetra, Fluquadri, Fluad Quad, Afluia Quad, Flucelvax Quad|BIOLOGICAL: SARS-CoV-2 vaccination: Comirnaty or Vaxzevria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brentuximab Vedotin Combined With Bendamustine Supercharge, a Low-toxicity and Efficient Salvage Regimen for Primary Refractory or First-relapsed Classic Hodgkin Lymphoma: Long-term Results of a Retrospective Monocenter Study.
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: OTHER: observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Empa Add on to Insulin in Japanese Patient With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: empagliflozin medium dose|DRUG: empagliflozin low dose|DRUG: empagliflozin high dose|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Atherosclerosis
Interventions: DEVICE: zotarolimus-eluting stent (ENDEAVOR®)|DEVICE: sirolimus-eluting stents (CYPHER SELECT® PLUS)|DEVICE: everolimus-eluting stents (PROMUS®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Tape vs Neuromuscular Stimulation For Conserative of Treatment Hemiplegic Shoulder
Status: COMPLETED
Conditions: Hemiplegia
Interventions: OTHER: NMES|OTHER: Kinesiotape|OTHER: Standardized Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on Self-adhesive Mesh for Open Inguinal Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: PROGRIP|DEVICE: POLYPROPYLENE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chungkookjang on Improvement of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Chungkookjang|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Placebo-Controlled, Double-blind Study of Tianshu Capsule in the Treatment of Migraine.
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Tianshu capsule|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Effects of Investigational Drug on Oxygenation in Healthy Volunteers Under Hypoxic Conditions
Status: TERMINATED
Conditions: Cardio-pulmonary Function
Interventions: DRUG: GBT440
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia
Status: COMPLETED
Conditions: Depression|Anxiety|Insomnia
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Trial to Determine the Safety and Efficacy of EMA401 in Patients With PHN
Status: WITHDRAWN
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: EMA401 200 mg|DRUG: EMA401 600 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1 Antihistamines
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: LOU064 (blinded)|DRUG: Placebo|DRUG: LOU064 (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-efficacy of Silver Diammine Fluoride in Erupting Molars
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: 30% silver diammine fluoride|BEHAVIORAL: Oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eficacia Ventilatoria y Remolacha
Status: RECRUITING
Conditions: SARS CoV 2 Infection|Muscle Disorder|Fatigue
Interventions: DIETARY_SUPPLEMENT: Remolacha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety and Efficacy Study of Tanezumab in Japanese Adult Subjects With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Celecoxib|BIOLOGICAL: Tanezumab 5 mg|BIOLOGICAL: Tanezumab 10 mg|DRUG: Placebo for celecoxib|BIOLOGICAL: Placebo for tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant Dimeglumine in Preventing Nausea and Vomiting in Patients With Gastrointestinal Cancer Receiving Combination Chemotherapy
Status: COMPLETED
Conditions: Gastrointestinal Cancer|Nausea Post Chemotherapy
Interventions: DRUG: fosaprepitant dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Atezolizumab Matching Placebo|DRUG: Tiragolumab Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GENERAL vs. REGIONAL ANESTHESIA ON SLEEP QUALITY FOR HIP ARTROPLASTY PATIENTS
Status: COMPLETED
Conditions: Sleep Disturbance|Postoperative Complications|Regional Anesthesia Morbidity
Interventions: PROCEDURE: General anesthesia with propofol induction and sevoflurane maintenance|PROCEDURE: Regional anesthesia with neuroaxial blockage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Pyramax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial Comparing Computerised Cognitive Exercises to Tetris in Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: OTHER: Scientific Brain Training (SBT)|OTHER: Tetris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Checkpoint Inhibitor Induced Colitis and Arthritis -Immunomodulation With IL-6 Blockade and Exploration of Disease Mechanisms
Status: COMPLETED
Conditions: Solid Tumor|Colitis|Arthritis
Interventions: DRUG: Tocilizumab (RoACTEMRA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
Status: RECRUITING
Conditions: Healthy|Renal Impairment
Interventions: DRUG: BI 456906
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetics and Safety of Oral Administration of BR9001 Compared With BR900A in Healthy Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BR9001|DRUG: BR900A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers
Status: COMPLETED
Conditions: Tobacco Use Cessation|Cancer Prevention
Interventions: DRUG: Nicotine Patch|BEHAVIORAL: Questionnaires|OTHER: Carbon Monoxide (CO) Test|BEHAVIORAL: Health Education and Handouts|BEHAVIORAL: Culturally Tailored Reading Materials|BEHAVIORAL: Counseling Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Cancer|Neoplasm, Prostate
Interventions: DRUG: Abiraterone acetate|DRUG: Apalutamide|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Acute Respiratory Distress Syndrome With Allogeneic Bone Marrow-derived Mesenchymal Stromal Cells
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome, Adult
Interventions: BIOLOGICAL: Mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Mammary Sentinel Lymph Node Biopsy in Early Breast Cancer Patients With Clinically Axillary Node -Negative
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: 99mTc-labeled Sulfur Colloid|PROCEDURE: Axillary Sentinel Lymph Node Biopsy|DRUG: Methylthioninium|DEVICE: Lymphoscintigraphy|PROCEDURE: Axillary Lymph Node Dissection|PROCEDURE: Internal Mammary Sentinel Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Deferoxamine for Iron Overload Before Allogeneic Stem Cell Transplantation
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: deferoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION