pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Use of Synthetic Mesh in Contaminated and Infected Abdominal Wall Repairs. A Long-term Prospective Clinical Trial
Status: COMPLETED
Conditions: Abdominal Wall Defect|Abdominal Wall Infection|Abdominal Wall Fistula|Infection
Interventions: PROCEDURE: Abdominal wall reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplement on the Intestinal Microbiota in Patients With Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Experimental Treatment, DCOOP Product, Hydroxytyrosol extract|DIETARY_SUPPLEMENT: Experimental Treatment,Indukern product, Curcumin and selenium extract|OTHER: Control Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE ENLIGHTEN STUDY
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DEVICE: Active Elipse Device|DEVICE: Elipse Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IOP Fluctuations in Patients With Primary Open-angle Glaucoma, Before and After Selective Laser Trabeculoplasty
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Pigmentary Glaucoma|Pseudoexfoliative Glaucoma
Interventions: DEVICE: Sensimed Triggerfish
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Home Exercise Delivery on Compliance & Outcomes for Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Pain|Compliance, Patient|Chronic Low Back Pain|Knee Pain Chronic
Interventions: OTHER: Number of Exercises|OTHER: Type of Instruction|OTHER: Delivery Type|OTHER: Mobile Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: HTX-011|DRUG: ropivacaine , epinephrine , ketorolac diluted in sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Nemvaleukin alfa|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Mirikizumab|DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Functional Brain Mapping in Psilocybin
Status: ACTIVE_NOT_RECRUITING
Conditions: Psilocybin
Interventions: DRUG: Psilocybin|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maternal Under-nutrition and Effect of Amaranth Grain Flat-bread on Anemia
Status: NOT_YET_RECRUITING
Conditions: Maternal Anemia in Pregnancy, Before Birth|Maternal; Malnutrition, Affecting Fetus
Interventions: COMBINATION_PRODUCT: Amaranth grain flat bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First Complementary Foods and the Infant Gastrointestinal Microbiota
Status: COMPLETED
Conditions: Healthy Participants|Infants|Gastrointestinal Microbiota
Interventions: OTHER: Infant fruit|OTHER: Infant vegetable|OTHER: Infant meat|OTHER: Infant grain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Concentration-Targeted Multidose Study of Atevirdine Mesylate ( U-87201E ), AZT, and ddI or ddC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atevirdine mesylate|DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pethema Multiple Myeloma 2000
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Alternating chemotherapy|PROCEDURE: Autologous Transplantation|DRUG: Maintenance|PROCEDURE: Second transplantation|PROCEDURE: ALOGENIC MINI TRASPLANTATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colonization and Persistence of Bifidobacterium Longum
Status: COMPLETED
Conditions: Bacterium; Agent
Interventions: DIETARY_SUPPLEMENT: Probiotic Powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Nitric Oxide in Cognition in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Glyceryl Trinitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia
Status: COMPLETED
Conditions: Fanconi Anemia
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Hematopoietic Stem Cell Transplantation|DRUG: Methylprednisolone|DRUG: Filgrastim|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Flu Vaccine Doses in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal iRInotecan, Carboplatin or oXaliplatin for Esophagogastric Cancer
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Liposomal Irinotecan|DRUG: Carboplatin|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: 5-fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LMT503 First-in-human SAD, MAD, and FE Study
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Disease|Colitis, Ulcerative|Crohn Disease
Interventions: DRUG: LMT503|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of the Venus P-Valve™ in the Pulmonic Position in Patients With Native Outflow Tracts
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Regurgitation
Interventions: PROCEDURE: trans catheter heart valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D in Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Vitamin D Deficiency
Interventions: DRUG: 1,25-Dihydroxyvitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robot Assisted Percutaneous Cardiovascular Intervention as a Strategy to Reduce or Risk of Intra-Procedure Contamination by COVID-19 and Other Respiratory Viruses
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Robot Assisted Percutaneous Cardiovascular Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|ERAS|Surgical Stomas|Ileostomy - Stoma|Colostomy Stoma
Interventions: PROCEDURE: Type of anaesthesia used
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Appeal and Impact of E-cigarettes in Smokers With SMI
Status: COMPLETED
Conditions: Tobacco Dependence|Schizophrenia|Bipolar Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: E-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas
Status: WITHDRAWN
Conditions: Contact Ulcer of Vocal Folds|Granuloma of Vocal Cords|Granuloma, Laryngeal|Granuloma
Interventions: DRUG: onabotulinumtoxinA|DRUG: omeprazole (proton pump inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-788 Followed by Evaluation of the Effects of a Low-Fat Meal on TAK-788 PK and Evaluation of Relative Bioavailability of TAK-788 Capsules in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-788|DRUG: Placebo|DRUG: TAK-788
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Caelyx Plus Carboplatin Versus Paclitaxel Plus Carboplatin in Patients With Epithelial Ovarian Cancer in Late Relapse
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elixir Medical Clinical Evaluation of the Novolimus-Eluting Coronary Stent System: A Randomized Study "EXCELLA II STUDY"
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Medtronic Endeavor Coronary Stent System|DEVICE: DESyne BD Novolimus Stent System|DEVICE: DESyne Novolimus Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: BI 456906|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Ultrasound-guided "Three-step" Radiofrequency Ablation for Giant Hepatic Hemangioma
Status: COMPLETED
Conditions: Hepatic Hemangioma
Interventions: PROCEDURE: "three-step" radiofrequency ablation|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: AGSAVI|DRUG: AGLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation and Reliability Testing of Dysphagia Trained Nurse Assessment
Status: COMPLETED
Conditions: Dysphagia Following Cerebral Infarction|Dysphagia Following Nontraumatic Intracerebral Hemorrhage
Interventions: DIAGNOSTIC_TEST: Dysphagia Trained Nurse Assessment (DTNAx)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study Comparing TAS-102 Versus Topotecan or Amrubicin to Treat Small Cell Lung Cancer Following Platinum-Based Chemotherapy
Status: TERMINATED
Conditions: Small Cell Lung Cancer (SCLC)
Interventions: DRUG: TAS-102|DRUG: Amrubicin (Japan)|DRUG: Topotecan (Japan/Europe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction (SVF) Injection in the Treatment of Patellar Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Patellar Tendinitis|Tendinopathy|Patellar Tendinopathy
Interventions: PROCEDURE: Stromal Vascular Fraction injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective and Retrospective Cohort Study of New Prognostic Factors With Peripheral Blood and Bone Marrow Evaluation at the Time of Diagnosis and During Treatment or Thereafter in Acute Leukemia (Acute Leukemia HSCT Cohort)
Status: UNKNOWN
Conditions: Acute Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CKD-828 S-Amlodipine Non-Responder Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: CKD-828 2.5/40mg|DRUG: CKD-828 2.5/80mg|DRUG: S-Amlodipine 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Pregabalin Premedication for Postoperative Pain Relief
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DRUG: placebo capsule (vitamin c)|DRUG: Group pregabalin 150|DRUG: Group pregabalin 300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Education in Patients With Non-oncological Orofacial Pain
Status: COMPLETED
Conditions: Oro-Facial-Digital Syndrome
Interventions: OTHER: Mindfulness + Education in Neurophysiology of pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanochemical Ablation Compared to Cyanoacrylate Adhesive
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: Mechanochemical ablation|PROCEDURE: Cyanoacrylate adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of 5 Low Volume Bowel Preparations
Status: COMPLETED
Conditions: Bowel Preparation for Colonoscopy
Interventions: DRUG: MiraLAX|OTHER: Gatorade|DRUG: MoviPrep|DRUG: SUPREP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL
Status: UNKNOWN
Conditions: Primary Vitreoretinal Lymphoma
Interventions: DRUG: Methotrexate|DRUG: Rituximab|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PIPAC-OPC7 Study: The Use of PET/CT Scans as a Method of Evaluation in Patients Treated With PIPAC, a Pilot Study.
Status: RECRUITING
Conditions: Peritoneal Cancer|Peritoneal Metastases|Peritoneal Carcinomatosis|Abdominal Cancer
Interventions: OTHER: scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine 10-20 mg|DRUG: Placebo|DRUG: SSRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Milvexian in Healthy Adult Females
Status: COMPLETED
Conditions: Healthy Female
Interventions: DRUG: Milvexian|DRUG: Midazolam|DRUG: Ethinylestradiol|DRUG: Drospirenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect Of Baduanjin Exercises In Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis, Idiopathic
Interventions: OTHER: Baduanjin Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacity of Deep Inspiration Breath Hold and Intensity-modulated Radiotherapy in Preventing PErfusion Defect for Left Sided Breast Cancer (EDIPE)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: myocardial perfusion SPECT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI
Status: COMPLETED
Conditions: Colorectal Cancer|Appendix Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Osseous Resection by Piezoelectric Device Versus Conventional Rotary Instruments
Status: UNKNOWN
Conditions: Healing Surgical Wounds
Interventions: PROCEDURE: osseous resection using piezoelectric device in surgical crown lengthening|PROCEDURE: Osseous resection using conventional rotary instruments in surgical crown lengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)
Status: COMPLETED
Conditions: Hypogonadism|Severe Obesity
Interventions: DRUG: Anastrazole|BEHAVIORAL: weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Interval Training on Exercise Capacity in Patients With Grown-up Congenital Heart Disease
Status: TERMINATED
Conditions: Congenital Heart Defects
Interventions: PROCEDURE: HIIT|OTHER: MICE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using SMART HOME Strategy to Reduce the Incidence of Delirium in the Intensive Care Unit
Status: NOT_YET_RECRUITING
Conditions: Delirium|Intensive Care Unit Delirium
Interventions: COMBINATION_PRODUCT: SMART HOME strategy|COMBINATION_PRODUCT: PADIS nursing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of OPEP on Mucus Plugging and Airflow Obstruction in Patients With Moderate-to-severe Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DEVICE: Aerobika OPEP device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Chronic Periodontitis in Smoker and Non- Smokers
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Lactobacillus brevis CD2 Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: CYT004-MelQbG10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Percutaneous Peripheral Nerve Stimulation and Performance
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: DEVICE: Percutaneous Peripheral Nerve Stimulation|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis
Status: RECRUITING
Conditions: AL Amyloidosis
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|PROCEDURE: Computed Tomography|DRUG: Dexamethasone|DRUG: Ixazomib Citrate|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Transabdominal Ultrasound|DRUG: Venetoclax|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCL
Status: RECRUITING
Conditions: NKTCL|Selinexor
Interventions: DRUG: Selinexor+pegaspargase+dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hamstring Stretching on Lumbar Muscle Activation in Officers
Status: NOT_YET_RECRUITING
Conditions: Office Workers|Muscle Tightness|Lumbar Region|Muscle Shortness|Stretch|Hamstring Flexibility
Interventions: OTHER: Active Static Hamstring Stretch Exercise|OTHER: Waiting List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canakinumab in Covid-19 Cardiac Injury (The Three C Study)
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2
Interventions: DRUG: Canakinumab Injection 600mg|DRUG: Canakinumab Injection 300mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma
Status: COMPLETED
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Cediranib|DRUG: Cediranib|DRUG: Lomustine Chemotherapy|DRUG: Placebo Cediranib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: Lerotinib|DRUG: Irinotecan/Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Safety Surveillance of Qizhi Tongluo Capsules:a Registry Study.
Status: RECRUITING
Conditions: Safety Surveillance|Adverse Drug Events|Adverse Drug Reactions|Severe Adverse Events|Severe Adverse Reactions
Interventions: DRUG: Qizhi Tongluo Capsules
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Catheter Ablation Versus Antiarrythmic Drugs for Atrial Fibrillation in China
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: catheter ablation|DRUG: Digaoxin,amiodarone,β receptor antagonist, Calcium Antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Liquid Toothpaste on Periodontal Disease
Status: COMPLETED
Conditions: Periodontitis|Gingivitis
Interventions: OTHER: DA-5502 liquid toothpaste|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Treat Patients With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006) plus Doxorubicin|DRUG: Doxorubicin/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole
Status: RECRUITING
Conditions: Weight Gain|Autism Spectrum Disorder|Medication Side Effect
Interventions: DRUG: Comparison of Risperidone and Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Study Comparing Aspirin and Effervescent Aspirin
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Acetylsalicylic Acid (Aspirin BAY1019036)|DRUG: Alka Seltzer Extra Strength|DRUG: Aspirin Migraine|DRUG: Aspirin Aspro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Blood Levels and Effects of AUT00201
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AUT00201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Sexually Transmitted Infection (STI) Results Notification and Partner Services
Status: COMPLETED
Conditions: Sexually Transmitted Infections
Interventions: OTHER: Call when test results are ready|OTHER: Text message when test results are ready|OTHER: Call and text message when test results are ready
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic Etiology
Status: RECRUITING
Conditions: Heart Failure|Microvascular Angina|Non-ischemic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: CMD test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adapting Diabetes Treatment Expert Systems to Patient in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Personalized Feedback|DEVICE: Decision Support System|DEVICE: Sensor Augmented Mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Zinc Gluconate as Treatment for Recalcitrant Cutaneous Warts: A Randomized, Double-blind, Placebo-controlled Trial
Status: COMPLETED
Conditions: Recalcitrant Cutaneous Warts
Interventions: DIETARY_SUPPLEMENT: Zinc gluconate|DIETARY_SUPPLEMENT: Corn starch pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Erlotinib and Capecitabine for Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Capecitabine|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty
Status: TERMINATED
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: Canaloplasty using the iTrack microcatheter with Healon GV Pro|DEVICE: Canaloplasty using the Omni surgical system with Healon GV Pro|DEVICE: Canaloplasty using the iTrack microcatheter with Healon Pro|DEVICE: Canaloplasty using the Omni surgical system with Healon Pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Pathologic Type, NIH and WHO Criteria,and Mechanism of GIST Malignant Transformation
Status: UNKNOWN
Conditions: Method of Differentiating Benignancy and Malignancy, Grading and Staging for GIST
Interventions: DRUG: Imatinib 400mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exergames in In-patient Rehabilitation
Status: COMPLETED
Conditions: Rehabilitation|Cardiovascular Diseases|Geriatric Patients|Parkinson Disease
Interventions: BEHAVIORAL: Dividat Senso Exergames
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer
Status: TERMINATED
Conditions: Advanced Biliary Tract Cancer|Intrahepatic Cholangiocarcinoma|Extrahepatic Cholangiocarcinoma|Gallbladder Carcinoma
Interventions: DRUG: Irinotecan Liposome Injection|DRUG: SG001|DRUG: Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurements of Diaphragmatic Mobility on COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Tongue Tamers as an Early Treatment of Anterior Open Bite
Status: COMPLETED
Conditions: Tongue Habits|Open Bite
Interventions: DEVICE: bonded tongue tamers|DEVICE: customized bonded spurs|DEVICE: conventional fixed palatal spurs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Probiotics to Reduce Antepartum Group B Streptococcus Colonization.
Status: ACTIVE_NOT_RECRUITING
Conditions: Group B Streptococcus Carrier in Childbirth|Gastrointestinal Symptoms
Interventions: BIOLOGICAL: Florajen3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and How the Body Handles a Single Dose of Subcutaneous (SC) and Intravenous (IV) Budigalimab in Adult Participants Living With Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: Budigalimab|DRUG: Placebo|DRUG: Budigalimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Different Treatment Regimens in Pulmonary Hypertension Secondary to Lung Disease and or Hypoxia
Status: UNKNOWN
Conditions: Pulmonary Hypertension Secondary to Lung Disease and/or Hypoxia
Interventions: DRUG: Sildenafil|DRUG: Bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chlorhexidine Plus Hyaluronic Acid Mouthwash in Surgical Wound Healing Following Third Molar Surgery (CLOR_4)
Status: RECRUITING
Conditions: Wound Heal|Surgical Wound|Impacted Third Molar Tooth
Interventions: DEVICE: Parallel Assignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: HFpEF - Heart Failure With Preserved Ejection Fraction
Interventions: BEHAVIORAL: HEART Camp|BEHAVIORAL: HEART Camp Connect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Tolerability of No7 in Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Solgar No7 Complex|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anlotinib Capsules in the Treatment for IPF/PF-ILDs
Status: RECRUITING
Conditions: Interstitial Lung Diseases
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Status: RECRUITING
Conditions: Pregnancy Related|Pregnancy Complications|Pregnancy, High Risk|Depression|Depression, Postpartum|Perinatal Depression|Anxiety|Anxiety in Pregnancy|Stress, Psychological|Racism|Discrimination, Racial|Inflammation
Interventions: DEVICE: MWSH plus Candlelit Care|DEVICE: MWSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Triple A Initiative Study ("Aktionsbündnis Akute Atemnot")
Status: TERMINATED
Conditions: Dyspnea|Heart Failure
Interventions: DEVICE: NTproBNP measurement with point of care device "Cobash232" in the POCT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Usefulness of Staining Lymph Nodes During Operations for Cancer Thyroid in Detecting the Nodes That Have Cancer
Status: COMPLETED
Conditions: Thyroid Cancer|Lymph Node Metastasis
Interventions: PROCEDURE: detecting lymph node metastasis by staining
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Internet-delivered Intervention Targeting Residual Cognitive Symptoms After Major Depressive Disorder
Status: UNKNOWN
Conditions: Cognitive Remediation|Cognitive Impairment|Major Depression in Remission
Interventions: BEHAVIORAL: RestDep: Internet-delivered intervention targeting residual cognitive symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparision of Midazolam-dexmedetomidine With Dexmedetomidine Alone for Hemodynamic Stability and Quality of Sedation in Elderly Patients Under Spinal Anesthesia
Status: WITHDRAWN
Conditions: Sedation; Aged; Hemodynamics
Interventions: DRUG: dexmedetomidine alone or dexmedetomidine + midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mueller Polarimetric Colposcopy for High-performance Detection of Cervical Changes During Pregnancy
Status: UNKNOWN
Conditions: Pregnancy Related|Premature Birth
Interventions: DEVICE: Mueller's polarimetric colposcopy "Group 1"|DEVICE: Mueller's polarimetric colposcopy "Group 2"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Peptide Cancer Vaccine To Treat HLA-A*24-positive Advanced Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: BIOLOGICAL: HLA-A*2402-restricted CDCA1 and KIF20A peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation Regiments in Patients With Prosthetic Heart Valve Thrombosis
Status: UNKNOWN
Conditions: Thrombosis
Interventions: DRUG: Warfarin|DRUG: Warfarin + ASA 100 mg + PPI|DRUG: Warfarin + ASA 300 mg + PPI|DRUG: Observational Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan
Status: COMPLETED
Conditions: Antepartum Hemorrhage|Postpartum Hemorrhage|Anemia|Eclampsia|Neonatal Sepsis|Birth Asphyxia|Diarrhoea|Pneumonia
Interventions: OTHER: Maternal Neonatal and Child Health Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Air Cleaner on the Indoor Allergen Sensitized Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DEVICE: PuriCare (HEPA Air Cleaner)|DEVICE: Mock device of PuriCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Short and Telematic Version of Cognitive-behavioral Treatment for Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectical Behavior Therapy -3-months|BEHAVIORAL: Dialectical Behavior Therapy -6-months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin
Status: ACTIVE_NOT_RECRUITING
Conditions: Various Advanced Cancer
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Cisplatin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Different Versions of the Best Possible Self Intervention
Status: COMPLETED
Conditions: General Population
Interventions: BEHAVIORAL: BPS PAST|BEHAVIORAL: BPS PRESENT|BEHAVIORAL: BPS FUTURE|BEHAVIORAL: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision
Status: UNKNOWN
Conditions: Cataract|Presbyopia|Astigmatism
Interventions: DEVICE: Intervention arm - Eyhance Toric II Intraocular Lens|DEVICE: Control Arm - Alcon IQ Toric Intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates
Status: TERMINATED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: optimized ibuprofen|DRUG: Standard Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial at Neoadjuvant Peritoneal and Systemic Chemotherapy Plus HIPEC in Gastric Carcinomatosis
Status: SUSPENDED
Conditions: Peritoneal Carcinomatosis|Gastric Cancer
Interventions: OTHER: Intraperitoneal and systemic chemotherapy plus maximum cytoreduction plus HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Curative Effect Evaluation Study of Treatment of Oral Deferiprone Tablets in Aceruloplasminaemia Patients
Status: UNKNOWN
Conditions: Aceruloplasminemia
Interventions: DRUG: Deferiprone treated
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Length Catheters vs Long Catheters in Peripheral Vein Cannulation.
Status: UNKNOWN
Conditions: Complications
Interventions: DEVICE: Standard Device for peripheral vein cannulation|DEVICE: Long Catheters for peripheral vein cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Biphasic Insulin Aspart Treatments in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 70|DRUG: biphasic insulin aspart 70|DRUG: biphasic insulin aspart 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estimating the Short-term Effectiveness of Online Advertisements for Improving Health
Status: COMPLETED
Conditions: Anorexia|Obesity|Smoking Cessation
Interventions: BEHAVIORAL: Ads display with target websites|BEHAVIORAL: Ads display with control websites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Stress in At Risk Mental State: Efficacy of Stress Management Cognitive Behavioral Therapy : a Randomized Controlled Trial"
Status: UNKNOWN
Conditions: Young Subjects With at Risk Mental States
Interventions: OTHER: Cognitive behavioral therapy|OTHER: Supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Apremilast Tablet|DRUG: Apremilast Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream
Status: COMPLETED
Conditions: Healthy Volunteers|Psoriasis
Interventions: DRUG: PBI-100 Topical Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic Exercise on Genetic Molecules
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Aerobic Exercise|Genetic Response
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dosing rTMS for Depression Post-SCI
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Depression|Depressive Disorder, Major
Interventions: DEVICE: repetitive transcranial magnetic stimulation--Active|DEVICE: repetitive transcranial magnetic stimulation--Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting|Laparoscopic Sleeve Gastrectomy|Morbid Obesity
Interventions: DRUG: Baclofen Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Status: ENROLLING_BY_INVITATION
Conditions: Pregnancy Complications|Acute Appendicitis|Acute Cholecystitis|Biliary Pancreatitis|Bowel Obstruction|Acute Diverticulitis
Interventions: PROCEDURE: non-obstetric acute general surgical disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Response Study of Transdermal Human Insulin in Patients
Status: NOT_YET_RECRUITING
Conditions: Glucose, High Blood
Interventions: BIOLOGICAL: Human Insulin|DEVICE: Finger-actuated, Metered Pump Sprayer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vallomix Socket Preservation Study
Status: NOT_YET_RECRUITING
Conditions: Alveolar Ridge Augmentation
Interventions: DEVICE: Allograft/Xenograft|DEVICE: Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Effect of a Whole Fruit Powder on Gut Microbiome Function on Overweight & Obese Adults
Status: RECRUITING
Conditions: Obesity|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Freeze-dried blueberries|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mako Functionally Aligned Total Knee Arthroplasty vs Mako Mechanically Aligned Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Osteoarthritis|Surgery
Interventions: DEVICE: Total knee arthroplasy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Chromium Picolinate on Insulin Sensitivity in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: chromium picolinate 1000 mcg daily vs placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT