pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Celecoxib On Restenosis After Coronary Intervention and Evolution of Atherosclerosis Trial
Status: UNKNOWN
Conditions: Angioplasty, Transluminal, Percutaneous Coronary|Coronary Restenosis
Interventions: DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial With Subcutaneous Immunotherapy in Depot Presentation in Patients With Allergic Rhinoconjunctivitis Sensitized to House Dust Mites
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Allergovac depot DPT/DF (50:50)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet for Colonoscopy Preparation in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Colonic Diseases
Interventions: DIETARY_SUPPLEMENT: Low-residue diet|DIETARY_SUPPLEMENT: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of HS-10517 in Chinese Adult Participants
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: HS-10517 Dose 1|DRUG: HS-10517 Dose 2|DRUG: HS-10517 Dose 3|DRUG: HS-10517 Dose 4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2)
Status: COMPLETED
Conditions: Leprosy
Interventions: DRUG: BE-PEP (Bedaquiline)|DRUG: SDR-PEP|DRUG: BE-PEP (Rifampicine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Screening for Advanced Heart Failure IN Stable ouTpatientS - The SAINTS Study
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Cardiopulmonary exercise test, NT-proBNP, Echocardiography, 6 minute walk test, Right heart catheterization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant Hypercholesterolemia
Status: WITHDRAWN
Conditions: Familial Hypercholesterolemia
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD)
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab and Decitabine for Patients With Relapsed/Refractory or Advanced NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: DRUG: Sintilimab|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-infusion of Unwashed Shed Blood During Off-pump Surgery
Status: RECRUITING
Conditions: Coronary Artery Disease|Blood Transfusion Complication|Cardiovascular Complication
Interventions: PROCEDURE: Re-infusion of unwashed shed blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celtra Duo Computer Assisted Design/Computer Assisted Machining (CAD/CAM) Dental Crown Study
Status: TERMINATED
Conditions: Fractured Tooth|Decayed Tooth|Unsatisfactory Restoration of Tooth
Interventions: DEVICE: Celtra Duo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Stage IV NSCLC
Interventions: DRUG: Poly ICLC|DRUG: IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Abdominal Binder Use on Postpartum Pain, Bleeding, and Breastfeeding Success in Cesarean Delivery Women
Status: UNKNOWN
Conditions: Cesarean Section
Interventions: DEVICE: Abdominal Binder|OTHER: Postpartum nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internal Plate Fixation vs. Plaster in Complete Articular Distal Radial Fractures
Status: COMPLETED
Conditions: Displaced Complete Articular Distal Radius Fractures
Interventions: PROCEDURE: Open reduction and internal plate fixation|OTHER: Closed reduction and plasterimmobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B-6 and Glutathione on Inflammation, Homocysteine, Oxidative Stress and Antioxidant Capacities
Status: UNKNOWN
Conditions: Liver Cirrhosis|Liver Cancer
Interventions: DIETARY_SUPPLEMENT: vitamin B-6|DIETARY_SUPPLEMENT: Glutathione|DIETARY_SUPPLEMENT: Dextrins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Adenomyosis and Pregnancy: Levonorgestrel vs. GnRH for Blastocyst Transfer
Status: COMPLETED
Conditions: Adenomyosis
Interventions: DRUG: Triptorelin|DEVICE: levonorgestrel-releasing intrauterine system|PROCEDURE: frozen embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Use of Dysport in Treatment of Vocal Tics in Patients With Tourette's Syndrome
Status: UNKNOWN
Conditions: Tourette Syndrome|Chronic Vocal Tic
Interventions: DRUG: Abobotulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Periviable GOALS Decision Support Tool
Status: RECRUITING
Conditions: Pregnancy Preterm|Premature Birth|Pregnancy Complications|Obstetric Labor, Premature|Obstetric Labor Complications
Interventions: OTHER: Periviable GOALS DST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Myofascial Induction and Therapeutic Pain Education in Chronic Low Back Pain
Status: COMPLETED
Conditions: Back Pain
Interventions: OTHER: Myofascial induction therapy|OTHER: Therapeutic pain education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adaptive COVID-19 Treatment Trial 2 (ACTT-2)
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Placebo|DRUG: Remdesivir|DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label, Single-Dose, Pharmacokinetic and Safety Study of E7080 (24 mg) Administered to Subjects With Mild, Moderate, and Severe Renal Impairment and to Healthy Subjects
Status: COMPLETED
Conditions: Renal Impairment|Disease Severity
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diode Laser and SRP in Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: PAPD+SRP|PROCEDURE: Sham-laser +SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ferric Carboxymaltose for Treatment of Anaemia of Cancer in Subjects With Multiple Myeloma Receiving Chemotherapy
Status: TERMINATED
Conditions: Iron-Deficiency Anemia
Interventions: DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Erosive Digital Osteoarthritis by Transcutaneous Auricular Nerve Stimulation
Status: COMPLETED
Conditions: Erosive Osteo-Arthritis|Hand Osteoarthritis
Interventions: DEVICE: active tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief
Status: UNKNOWN
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Occlusive Hydrocolloid Silver-containing Wound Dressing After Sternotomy Reduce Surgical Side Infection After Cardiac Surgery?
Status: COMPLETED
Conditions: Surgical Site Infection; Cardiac Surgery; Advanced Dressing; Postoperative Care
Interventions: COMBINATION_PRODUCT: Aquacel Ag Surgical®|OTHER: Standard Care (sterile gauze and adhesive tape)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adrenal Function and Use of Intralesional Triamcinolone Acetonide 10 mg/mL (Kenalog-10) in Patients With Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Triamcinolone Acetonide 10 mg/mL (Kenalog-10)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparison of Bizact With Electroscissor for Tonsillectomy
Status: UNKNOWN
Conditions: Tonsillar Hypertrophy, Tonsillitis
Interventions: DEVICE: tonsillar dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Cognitive Remediation Outcomes in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychosis
Interventions: OTHER: Targeted Cognitive Training|OTHER: Social Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saxagliptin and Cardiac Structure and Function
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent|Heart Failure
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Maintenance
Status: COMPLETED
Conditions: Osteoarthritis|Obesity
Interventions: DRUG: Liraglutide 3 mg (Saxenda)|DRUG: Liraglutide 3 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pilot Study of Medical Device-Neuclare for Patients With Idiopathic Normal Pressure Hydrocephalus (iNPH)
Status: RECRUITING
Conditions: Idiopathic Normal Pressure Hydrocephalus (iNPH)
Interventions: DEVICE: Neuclare
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader Willi Syndrome|Adrenal Insufficiency
Interventions: OTHER: Low dose (1 mcg) ACTH stimulation test|OTHER: Overnight metyrapone test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy
Status: RECRUITING
Conditions: Penile Cancer|Advanced Cancer|Metastatic Cancer
Interventions: DRUG: Avelumab|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FDG-PET-Stratified R-DICEP and R-Beam/ASCT For Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: PROCEDURE: Autologous Blood Stem Transplantation|DRUG: R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Adherence Intervention to Reach Glycemic Control With Insulin Therapy for Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Low intensity|OTHER: Moderate intensity|OTHER: High intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Compound Herbal Formula (TPE-1) for Leukopenia and Cancer-related Fatigue in Breast Cancer Patients With Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer|Radiotherapy|Chinese Herbal Medicine
Interventions: DRUG: Chinese herbal medicine decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Belimumab in the Prevention of Kidney Transplant Rejection
Status: COMPLETED
Conditions: Transplantation, Organ
Interventions: DRUG: Belimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exparel (TM) on Post-operative Pain After Laparoscopic Gastric Bypass Using Circular EEA Stapler
Status: COMPLETED
Conditions: Post-operative Pain Management
Interventions: DRUG: Exparel|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Qualification of Methods for Analyzing the Mucosal Immune Response to COVID-19
Status: NOT_YET_RECRUITING
Conditions: Certain Disorders Involving the Immune Mechanism
Interventions: BIOLOGICAL: Sampling|BIOLOGICAL: PCR (polymerase chain reaction) SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Pharmacokinetics Study of CNTO 3157 in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: 100 mg CNTO 3157|BIOLOGICAL: 300 mg CNTO 3157|BIOLOGICAL: 600 mg CNTO 3157|BIOLOGICAL: 300 mg CNTO 3157|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Merkel Positron Emission Tomography (PET) Protocol
Status: COMPLETED
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks
Status: COMPLETED
Conditions: Cervical Preparation
Interventions: DRUG: Mifepristone|DEVICE: osmotic dilators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Androgen Receptor and Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female|Triple Negative and Androgen Receptor Positive
Interventions: DRUG: Darolutamide|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Counting and DASH Intervention and Pregnancy Outcomes Among Women With Gestational Diabetes
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus With Baby Delivered
Interventions: BEHAVIORAL: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
Status: COMPLETED
Conditions: Pregnancy|Malaria in Pregnancy|Malaria
Interventions: DRUG: dihydroartemisinin-piperaquine|DRUG: sulphadoxine-pyrimethamine|DRUG: dihydroartemisinin-piperaquine plus azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CLUSTER-HF: Lung Ultrasound Guided Therapy in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: COMBINATION_PRODUCT: LUS-guided therapy|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging of the Angiofibrotic Switch in Neovascular AMD
Status: UNKNOWN
Conditions: Age-related Macular Degeneration|Choroidal Neovascularization
Interventions: DIAGNOSTIC_TEST: Best-corrected Visual acuity testing (BCVA)|DIAGNOSTIC_TEST: Optical coherence tomography (OCT)|DIAGNOSTIC_TEST: Color fundus photography (CFP)|DIAGNOSTIC_TEST: Optical coherence tomography angiography (OCTA)|DIAGNOSTIC_TEST: Polarization-sensitive optical coherence tomography (PS-OCT)|DIAGNOSTIC_TEST: Microperimetry (MP)|DIAGNOSTIC_TEST: Adaptive-optics optical coherence tomography (AO-OCT)|DIAGNOSTIC_TEST: Fluorescein angiography (FA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: T/QT Study to Investigate the Effect of Relacorilant on Cardiac Repolarization in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Relacorilant|DRUG: Placebo to relacorilant|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Starting a Dolutegravir-based Regimen on HIV-1 Proviral DNA Reservoir Of Treatment Naïve and Experienced Patients
Status: UNKNOWN
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of 5-Fluorouracil Given With 776C85 (GW776) and Low-Dose Leucovorin in Adult Patients With Solid Tumors
Status: COMPLETED
Conditions: Lymphoma|Neoplasms
Interventions: DRUG: 5-Fluorouracil|DRUG: Ethynyluracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Decision Aid for Education and Support About Cancer Treatment
Status: COMPLETED
Conditions: Cancer|Childhood Cancer
Interventions: BEHAVIORAL: Decision Aid for Education and Support about Cancer Treatment (DECIDES)|BEHAVIORAL: Decision Aid for Education and Support about Cancer Treatment with Coach-Assisted Support (DECIDES + coach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura
Status: COMPLETED
Conditions: Migraine|Headaches
Interventions: DRUG: 100 mg Sumatriptan Tablet and OPTINOSE Placebo delivered nasally|DRUG: OPTINOSE SUMATRIPTAN delivered nasally and placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Utility of Exercise Cardiac Magnetic Resonance in the Assessment of Cardiac Dyspnea.
Status: COMPLETED
Conditions: Shortness of Breath|Cardiac; Dyspnea
Interventions: DIAGNOSTIC_TEST: Exercise cardiac magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison Between Cardiovascular Exercise Modes Following Sport Related Concussion
Status: TERMINATED
Conditions: Concussion, Mild|Sport Injury
Interventions: OTHER: Aerobic (treadmill) Exercise|OTHER: Dynamic (Agility) Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Allogeneic CARCIK-CD19 in Adults/Pediatric B-cell NHL or Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: B-cell NHL|CLL
Interventions: BIOLOGICAL: CARCIK-CD19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR Mutation
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Vinorelbine+Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of UC-781 Vaginal Microbicide
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Placebo gel|DRUG: UC 781
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma
Status: WITHDRAWN
Conditions: Malignant Glioma
Interventions: BIOLOGICAL: PVSRIPO|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Transfusion-dependent Alpha-Thalassemia|Transfusion-dependent Beta-Thalassemia
Interventions: DRUG: Placebo Matching Mitapivat|DRUG: Mitapivat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREvention of Intrauterine Adhesion After Adhesiolysis With Novel Tri-block deGradable Polymer Film.
Status: ACTIVE_NOT_RECRUITING
Conditions: Asherman Syndrome|Intrauterine Adhesion
Interventions: DEVICE: Womed Leaf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab in Treating Young Patients Who Are Receiving Chemotherapy for B-Cell Non-Hodgkin's Lymphoma or B-Cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-heated Resin Composite Restoration
Status: COMPLETED
Conditions: The Effect of Preheating Cycles of Resin Composite on Both Hypersensitivity and Clinical Performance
Interventions: PROCEDURE: Pre-heating of resin composite before application|PROCEDURE: no pre-heating of resin composite before application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Neoplasms|Prostatic Neoplasms
Interventions: DRUG: cabazitaxel (XRP6258) (RPR116258)|DRUG: mitoxantrone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia With Myelodysplasia Related Disease and < 30% Blasts|Mixed Myelodysplastic/Myeloproliferative Disease
Interventions: DRUG: Azacitidine|OTHER: Donor lymphocytes|OTHER: Tapering of immune suppression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Carcinoma|Cancer of Breast|Malignant Tumor of Breast
Interventions: DRUG: Palbociclib|DRUG: Letrozole|DRUG: Fulvestrant|PROCEDURE: Optional research biopsy|DRUG: Goserelin|PROCEDURE: Research blood draw|PROCEDURE: Circulating tumor cell blood draw|PROCEDURE: Tumor biopsy (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-intensity Pulsed Ultrasound on Pain and Functional Disability in Patients With Lumbar Spondylolysis
Status: COMPLETED
Conditions: Spondylolysis
Interventions: DEVICE: Low-intensity pulsed ultrasound (LIPUS)|OTHER: Routine physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Stabilizing Splint Versus Pivot Splint as Jaw Exercise Together With Stabilizing Splint
Status: UNKNOWN
Conditions: TMJ Disc Disorder
Interventions: DEVICE: pivot splint|DEVICE: stabilizing splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral 30 % Dextrose and iv Midazolam Sedation During MRI in Neonates
Status: UNKNOWN
Conditions: Epilepsy|Trauma|Metabolic Disease
Interventions: OTHER: oral 30% glucose|DRUG: IV midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bladder Sparing Treatment of Tislelizumab, Gemcitabine and Cisplatin for Patients With PD-L1 Positive Muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Urothelial Carcinoma Bladder|PD-1 Inhibitor
Interventions: DRUG: Tislelizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga or Educational Wellness Class for Women With Stage I, Stage II, or Stage III Breast Cancer Undergoing Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Depression|Fatigue|Sleep Disorders
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.
Status: UNKNOWN
Conditions: Anorexia
Interventions: DRUG: Mirtazapine|DRUG: Megestrol Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotics Study in Preterm Premature Rupture of the Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of the Membranes
Interventions: DRUG: cefazolin, erythromycin, clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: PPP treatment|BIOLOGICAL: PRP treatment|BIOLOGICAL: PRP and PL Combo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Allopurinol and Dypiridamole in Acute Mania
Status: COMPLETED
Conditions: Mania
Interventions: DRUG: Allopurinol|DRUG: Dipyridamole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PANOVISION: Feasibility and Safety of Hybrid IVUS-OCT System
Status: COMPLETED
Conditions: Coronary Artery Disease|Intravascular Imaging Device
Interventions: DIAGNOSTIC_TEST: Intravascular ultrasound|DIAGNOSTIC_TEST: Optical coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Tumor
Interventions: BIOLOGICAL: iNeo-Vac-P01|OTHER: GM-CSF|DRUG: PD-1|PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of SARS-CoV-2 Vaccine (Vero Cells), Inactivated in Healthy Population Aged 3 to 17 Years(COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Vaccine (Vero Cells), Inactivated|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Subcutaneous Reinjection of Human Autologous Adipose-derived Stromal Vascular Fraction (Celution® System) in the Hands of Patients Suffering From Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: OTHER: the cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of NESA in the Treatment of Cancer Survivors
Status: RECRUITING
Conditions: Cancer Survivors
Interventions: DEVICE: Non-invasive Neuromodulation|DEVICE: Placebo Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Cervical Discectomy and Fusion (ACDF) - Behavioral Intervention
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: Proactive pharyngeal-laryngeal Exercise Program|DIETARY_SUPPLEMENT: Premier Protein Clear ® High Protein|BEHAVIORAL: Hydration Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial Evaluating the Role of Systemic Antihistamine Therapy in the Reduction of Adverse Effects Associated With Topical 5-aminolevulinic Acid Photodynamic Therapy
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Antihistamine Cetirizine Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition?
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: OTHER: elemental formula Elecare®|OTHER: partially hydrolyzed formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment
Status: RECRUITING
Conditions: Spinal Cord Tumors
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Elastography|PROCEDURE: Assessment and Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Oral Sucrose and Topical Anesthetics to Reduce Pain During Eye Examination for Retinopathy of Prematurity
Status: COMPLETED
Conditions: Investigate the Efficacy of Sucrose During Eye Examination
Interventions: DIETARY_SUPPLEMENT: Oral sucrose solution|DIETARY_SUPPLEMENT: Steril water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic Stewardship in Small Hospitals
Status: COMPLETED
Conditions: Inappropriate Prescribing|Antibiotic Stewardship|Anti-Bacterial Agents
Interventions: BEHAVIORAL: Program 1|BEHAVIORAL: Program 2|BEHAVIORAL: Program 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transdermal Continuous Oxygen Therapy for Infection Prophylaxis in High- Risk Patients Undergoing Instrumented Fusion
Status: WITHDRAWN
Conditions: Instrumented Spinal Fusion
Interventions: DEVICE: EPIFLO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on Safety and Efficacy of Tocilizumab (RoActemra/Actemra) Alone or in Combination With Non-Biologic Antirheumatics in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Non-Biologic DMARDs|DRUG: Tocilizumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: BCD-180, dose 1|BIOLOGICAL: BCD-180, dose 2|BIOLOGICAL: BCD-180, dose 3|BIOLOGICAL: BCD-180, dose 4|BIOLOGICAL: BCD-180, dose 5|BIOLOGICAL: BCD-180, dose 6|BIOLOGICAL: BCD-180, dose 7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can Digitally Delivered First-line Osteoarthritis Treatment Improve Equal Access to Care
Status: RECRUITING
Conditions: Health Services Accessibility|First-line Treatment|Osteoarthritis
Interventions: BEHAVIORAL: Digitally delivered first-line treatment for osteoarthritis|BEHAVIORAL: Face-to-face first-line treatment for osteoarthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mandibular Advancement Clear Aligner Treatment in Juvenile Idiopathic Arthritis Subjects
Status: NOT_YET_RECRUITING
Conditions: Juvenile Idiopathic Arthritis|Malocclusion, Angle Class II
Interventions: DEVICE: Device: orthodontic - mandibular advancement clear aligner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Arm Study of BSI-201 in Patients With BRCA-1 or BRCA-2 Associated Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Cancer|Advanced Epithelial Ovarian Cancer
Interventions: DRUG: Iniparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Nerve Block Following Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Post-op Pain
Interventions: DRUG: Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed.|DRUG: For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Popliteal Artery Entrapment Syndrome & TRanscutaneoUS Oxymetry
Status: COMPLETED
Conditions: Popliteal Entrapment Syndrome
Interventions: DIAGNOSTIC_TEST: Transcutaneous oximetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of a Totally Synthetic High Fidelity Laparoscopic Duodenal Atresia (DA) Surgical Simulator
Status: UNKNOWN
Conditions: Duodenal Atresia
Interventions: PROCEDURE: Performance of laparoscopic duodenal atresia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Galinpepimut-S|DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Decitabine|DRUG: Cytarabine|OTHER: Observation|BIOLOGICAL: GM-CSF|OTHER: Montanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine vs EMDR to Treat Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Fluoxetine|BEHAVIORAL: EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin plus Placebo|DRUG: Metfomin plus Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRINCE: Study of Atazanavir (ATV)/Ritonavir (RTV)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir powder|DRUG: Ritonavir oral solution|DRUG: Atazanavir capsules|DRUG: Ritonavir capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of COVID-19 Vaccine EuCorVac-19 in Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: EuCorVac-19|BIOLOGICAL: ChAdOx1 nCoV-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: rTMS and Body Shape Perception
Status: TERMINATED
Conditions: Anorexia Nervosa
Interventions: PROCEDURE: Sham rTMS|PROCEDURE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-segmental Robotic and Technological Upper Limb Rehabilitation in Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Amadeo, Pablo, Diego and Motore.|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maximizing the Initial Experience of a Neophyte Scleral Lens Wearer
Status: TERMINATED
Conditions: Contact Lens Adaptation
Interventions: DEVICE: DMV inserter (DMV® MagicTouch™) with an open end|DEVICE: DMV inserter (DMV® MagicTouch™) with a closed end|DEVICE: Three fingers (Patient's Hand)|DEVICE: O-ring (Hardware Store Product)|DEVICE: Tea light candle (Generic Deparment Store Product) with DMV inserter (DMV® MagicTouch™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose-Titration Study of GK Activator (2) in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: GK Activator (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colorectal Metastasis and Liver Transplantation With Organs From Deceased Donors
Status: RECRUITING
Conditions: Colorectal Liver Metastases|Colorectal Adenocarcinoma|Unresectable Malignant Neoplasm
Interventions: PROCEDURE: Liver Transplant|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Necessity for Repetitive Education of Behavioral Modification
Status: COMPLETED
Conditions: Patients Who Had the Urine Volume at Nighttime More Than One Third of Total Daily Urine Volume (NPU) and Voided More Than Two Times at Nighttime (Nocturia)
Interventions: OTHER: education for behavioral modification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds
Status: TERMINATED
Conditions: Diabetic Foot Ulcers|Venous Ulcers|Pressure Ulcers
Interventions: DEVICE: Autologous PRP Gel|DEVICE: Autologous PRP Injections|DEVICE: Autologous PRP Gel plus PRP Injections|PROCEDURE: Standard Wound Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MOM Program: 5 Year Follow-up Study of a Home Visiting Program at The Children's Hospital of Philadelphia
Status: COMPLETED
Conditions: Child Development
Interventions: BEHAVIORAL: Home visiting professional support model|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Risperidone Monotherapy in Bipolar Anxiety
Status: COMPLETED
Conditions: Bipolar Disorder|Panic Disorder|Generalized Anxiety Disorder
Interventions: DRUG: risperidone (Risperdal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Marine Protein Hydrolysate in Healthy Adults
Status: COMPLETED
Conditions: Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Cod protein hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy and Safety Study of T-62 in Subjects With Postherpetic Neuralgia
Status: TERMINATED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: T-62 Dose 1|DRUG: T-62 Dose 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA
Status: RECRUITING
Conditions: Osteoarthritis, Hip
Interventions: DRUG: Autologous Adipose Derived Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Need-focused Single Session Intervention
Status: RECRUITING
Conditions: Depression and/or Anxiety in the Mild-to-moderate Range
Interventions: BEHAVIORAL: Clinician-administered Need-focused Single Session Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Retrovirals for Kaposi's Sarcoma
Status: COMPLETED
Conditions: Kaposi's Sarcoma|HIV Infections
Interventions: DRUG: Lopinavir/ritonavir plus Emtricitabine/Tenofovir versus Efavirenz plus Emtricitabine/Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers
Status: COMPLETED
Conditions: Glioblastoma|Malignant Glioma|WHO Grade III Glioma
Interventions: OTHER: Palliative Therapy|OTHER: Quality-of-Life Assessment|OTHER: Supportive Care|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Fampridine-ER Tablets in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Dalfampridine-ER 5mg|DRUG: Dalfampridine-ER 10mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of INI-2004 in Healthy Volunteers and Participants With Allergic Rhinitis.
Status: RECRUITING
Conditions: Allergic Rhinitis Due to Weed Pollen|Allergic Rhinitis
Interventions: DRUG: INI-2004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT