pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Low-Dose Ketamine Infusion During Burn Wound Care
Status: RECRUITING
Conditions: Burn|Pain|Dissociation|Opioid
Interventions: DRUG: Ketamine|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)
Status: COMPLETED
Conditions: Liver Cirrhosis, Biliary
Interventions: DRUG: Placebo|DRUG: Obeticholic Acid (OCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GLAD: Dose-Finding, Efficacy, and Safety of AZ 242 (Tesaglitazar) in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tesaglitazar|DRUG: Pioglitazone|BEHAVIORAL: Dietary and Lifestyle Modification Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dynamic PET/CT Evaluated the Response of Neoadjuvant Anti-PD1 Combination With Chemotherapy for Ⅱa-Ⅲb NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage II|Non-small Cell Lung Cancer Stage III|PET/CT
Interventions: DRUG: pembrolizumab, pemetrexed, gemcitabine, cisplatin, carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Intravenous Ampion in Adult COVID-19 Patients Requiring Supplemental Oxygen
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: Ampion|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsed Magnetic Pads on Rheumatoid Arthritis Symptoms in Postmenopausal Women
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Menopause
Interventions: DEVICE: Pulsed magnetic field pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Use of Progesterone to Reduce Preterm Birth
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Progesterone (OHP17)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome
Status: TERMINATED
Conditions: Hemolytic Uremic Syndrome
Interventions: DRUG: SYNSORB Pk|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tinnitus Sound Therapy Using Mobile Application.
Status: NOT_YET_RECRUITING
Conditions: Tinnitus
Interventions: BEHAVIORAL: Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability and Efficacy of ISIS-GCCRRx in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ISIS-GCCRRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants
Status: RECRUITING
Conditions: Ductus Arteriosus, Patent
Interventions: DEVICE: Percutaneous Patent Ductus Arteriosus Closure (PPC)|COMBINATION_PRODUCT: Responsive Management Intervention|DIAGNOSTIC_TEST: Echocardiogram, cardiac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Irritability Associated With Autism Spectrum Disorder (ASD)
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EP Combined With RFA for Ampullary Neoplasms With Intraductal Biliary Extension
Status: COMPLETED
Conditions: Ampullary Adenomas
Interventions: PROCEDURE: Endoscopic Papillectomy|PROCEDURE: Endobiliary Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Oxygen|OTHER: High flow of room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl-L-Leucine for GM2 Gangliosidosis (Tay-Sachs and Sandhoff Disease)
Status: COMPLETED
Conditions: GM2 Gangliosidosis|Tay-Sachs Disease|Sandhoff Disease
Interventions: DRUG: IB1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: sitagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Response to Certolizumab Pegol Treatment by Functional MRI of the Brain
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Certolizumab Pegol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, Cisplatin, and Radiation Therapy in Treating Patients With Stage II, Stage III, or Stage IV Nasopharyngeal Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: EXPAREL|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: OTHER: Robust Radiotherapy planning|OTHER: Margin-Based Radiotherapy planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Total intravenous anesthesia|DRUG: Total intravenous anesthesia plus palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reduction of Mitral Regurgitation With the SATURN Trans-Septal Transcatheter Mitral Valve Replacement (TMVR) System in Patients With Severe Symptomatic Mitral Regurgitation
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Transcatheter mitral valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: irradiation therapy|BIOLOGICAL: G-CSF|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SynKIR-310 for Relapsed/Refractory B-NHL
Status: NOT_YET_RECRUITING
Conditions: B Cell Lymphoma|NHL, Adult|Mantle Cell Lymphoma|Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Aggressive B-Cell Non-Hodgkin Lymphoma|Indolent B-Cell Non-Hodgkin Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|DLBCL - Diffuse Large B Cell Lymphoma|HGBL With MYC and BCL2 and/or BCL6 Rearrangements|High-grade B-cell Lymphoma|Diffuse Large B Cell Lymphoma|Large B-cell Lymphoma|T-Cell/Histiocyte Rich Lymphoma|Non-hodgkin Lymphoma,B Cell|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|Epstein-Barr Virus Positive DLBCL, Nos|Follicular Lymphoma Grade 3B|DLBCL (Diffuse Large B-Cell Lymphoma) Associated With Chronic Inflammation|High Grade B-Cell Lymphoma, Not Otherwise Specified|Follicular Lymphoma Grade 3|Marginal Zone Splenic Lymphoma|DLBCL
Interventions: BIOLOGICAL: SynKIR-310
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Protocols for Deflation of Radial Band Following Coronary Procedures Via the Radial Artery
Status: COMPLETED
Conditions: Coronary Artery Disease|Radial Artery Injury
Interventions: DEVICE: Late deflation of TR band|DEVICE: Early deflation of TR band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of the COVID-19 Vaccine Candidates VBI-2902a and VBI-2905a
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: VBI-2902a|BIOLOGICAL: Placebo|BIOLOGICAL: VBI-2905a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of Rifampicin, Ketoconazole, and Omeprazole on the Pharmacokinetics of Sativex
Status: COMPLETED
Conditions: Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Known Inducer of CYP3A4|Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a Potent Inhibitor of CYP3A4|Evaluation of Pharmacokinetics of Sativex in the Absence and Presence of a CYP2C19 Inhibitor
Interventions: DRUG: Sativex and rifampicin|DRUG: Sativex and rifampicin|DRUG: Sativex and ketoconazole|DRUG: Sativex and ketoconazole|DRUG: Sativex and omeprazole|DRUG: Sativex and omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conduction System Pacing Versus Biventricular Pacing for Cardiac resYNChronization
Status: ACTIVE_NOT_RECRUITING
Conditions: Dilated Cardiomyopathy With Conduction Defect|Left Bundle-Branch Block|Heart Failure|Resynchronization Therapy|Cardiac Remodeling, Ventricular
Interventions: DEVICE: Resynchronization with conduction system pacing|DEVICE: Cardiac resynchronization therapy with biventricular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Strategies for Management of Duchenne Myopathy (DM)
Status: UNKNOWN
Conditions: Myopathy
Interventions: DRUG: Sildenafil (Phosphodiesterase inhibitors)|DRUG: Prednisolone (Steroids)|PROCEDURE: Mesenchymal stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A/H1N1 Immunogenicity and Safety in Adults
Status: COMPLETED
Conditions: Influenza|Pandemic Influenza
Interventions: BIOLOGICAL: H1N1 pandemic influenza vaccine (whole virion, Vero Cell-derived, inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation Study of Safety and Performance of the Sentio System.
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss, Conductive|Hearing Loss, Mixed|Hearing Loss, Unilateral
Interventions: DEVICE: Active transcutaneous bone conduction hearing system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of an Investigational Pneumococcal Vaccine in the Elderly Population
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: 11-valent pneumococcal vaccine GSK513026|BIOLOGICAL: Pneumo 23™|BIOLOGICAL: Placebo|BIOLOGICAL: 10-valent pneumococcal vaccine GSK513026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases
Status: COMPLETED
Conditions: Preeclampsia|Pregnancy|Micronutrients|Exercise
Interventions: BEHAVIORAL: Regular aerobic physical exercise|DIETARY_SUPPLEMENT: Micronutrients|OTHER: Activities of daily living + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MA+AZA Regimen for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: mitoxantrone liposome, Ara-Cytarabine and azacitidine|DRUG: Daunorubicin,Ara-Cytarabine, azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Aclidinium/Formoterol on Nighttime Lung Function and Morning Symptoms in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: ACL/FOR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Weight Loss|Non-alcoholic Steatohepatitis (NASH)
Interventions: BEHAVIORAL: Lifestyle modification|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roll Over Study From 1199.30 BIBF 1120 in Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: BIBF 1120|DRUG: BIBF 1120|DRUG: BIBF 1120|DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Aspirin After Preeclampsia: TAP Trial
Status: RECRUITING
Conditions: Hypertensive Disorder of Pregnancy|Pre-Eclampsia|Hypertension|Eclampsia|Gestational Hypertension|Cardiovascular Diseases|Toxemia|Pregnancy Complications|Vascular Diseases|Hypertension, Pregnancy Induced|Hypertension;Pre-Eclamptic
Interventions: DRUG: Low-dose aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of ADDERALL XR in the Treatment of Adolescents Aged 13-17 With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Mixed salts of a single-entity amphetamine (ADDERALL XR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 99m Tc-3PRGD2 SPECT/CT Imaging in the Diagnosis of Lymph Node Metastasis of Esophageal Carcinoma
Status: UNKNOWN
Conditions: Esophageal Cancer|Lymph Node Metastases|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: 99mTc-3PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of NBI-98854 in Adults With Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: NBI-98854|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Fecal Microbiota Transplant in Chronic Intestinal Pseudo-obstruction Patients
Status: COMPLETED
Conditions: Intestinal Pseudo-Obstruction|Fecal Microbiota Transplantation
Interventions: OTHER: sequential fecal microbiota transplant combined with small intestinal fluid transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy
Status: TERMINATED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: panobinostat|DRUG: fluorouracil|DRUG: leucovorin calcium|PROCEDURE: biopsy|GENETIC: reverse transcriptase-polymerase chain reaction|GENETIC: western blotting|OTHER: laboratory biomarker analysis|GENETIC: gene expression analysis|GENETIC: RNA analysis|GENETIC: polymorphism analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: ATG|DRUG: CTX|DRUG: Mycophenolate Mofetil|DRUG: Ciclosporin A (CsA)|DRUG: methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Efficiency and Effectiveness of Two Types of Bonded Orthodontic Retainers: an RCT.
Status: COMPLETED
Conditions: Relapse
Interventions: DEVICE: Twistflex retainer|DEVICE: Orthoflex retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infection Rate of One-Stage Bilateral TKR - One Surgeon Sequential vs. Two Surgeon Simultaneous: A Randomized Controlled Study
Status: UNKNOWN
Conditions: Infection Joint|Joint Infection|Arthroplasty Complications
Interventions: PROCEDURE: Simultaneous bilateral total knee arthroplasty|PROCEDURE: Sequenced bilateral TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Femoral Block With Levobupivacaine 0.125% or Ropivacaine 0.2% in Elderly Patients With Femoral Fractures
Status: UNKNOWN
Conditions: Femur Fracture|Hip Fractures
Interventions: PROCEDURE: continuous femoral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Phase III, Randomized, Double-blind, Prospective and Comparative to Evaluate the Efficacy and Tolerability of Using APETIVITON BC Compared to Petivit BC in Appetite Stimulate.
Status: UNKNOWN
Conditions: Inappetence
Interventions: DRUG: Apetiviton BC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NTM-LD Treatment Based on GenSeizer Characteristic Gene Capture Strategy
Status: UNKNOWN
Conditions: Non - Tuberculosis Mycobacteria Lung Disease
Interventions: DIAGNOSTIC_TEST: Genotype detected through GenSeizer high-throughput gene capture technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Fatty Acids From Krill Oil and Krill Meal and Fatty Acids From Fish Oil in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Krill oil|DIETARY_SUPPLEMENT: Krill meal|DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin.
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease
Interventions: DRUG: Ofloxacin|DRUG: Avelox (Moxifloxacin, BAY12-8039)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Analgesia in Caesarean Section Using Intravenous Paracetamol
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Paracetamol|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term-opioid-free Anesthesia in Anterior Cervical Surgery
Status: COMPLETED
Conditions: Long-term-opioid-free Anesthesia
Interventions: DRUG: Remifentanil Hydrochloride|DRUG: Sufentanil Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
Status: NOT_YET_RECRUITING
Conditions: Insomnia|Postoperative Delirium|Delayed Neurocognitive Recovery|Postoperative Neurocognitive Disorder
Interventions: BEHAVIORAL: digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)|BEHAVIORAL: Sleep Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chidamide and Venetoclax for Retinoic Acid and Arsenic Resistant Acute Promyelocytic Leukemia
Status: RECRUITING
Conditions: APL
Interventions: DRUG: Chidamide+venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for Abdominal Pain From Adhesions
Status: TERMINATED
Conditions: Abdominal Pain|Surgical Adhesions
Interventions: DRUG: Pregabalin 75 or 150 mg BID for 7 weeks followed by open label pregabalin 150 mg BID for 4 weeks|DRUG: Placebo first followed by open label pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment and Monitoring of Renal Proximal Tubular Tolerance of Nucleoside and Nucleotide Analogues Using Early Screening Tools in Patients Chronically Mono-infected With Hepatitis B Virus
Status: COMPLETED
Conditions: Hepatitis B|Renal Failure With Tubular Necrosis
Interventions: BIOLOGICAL: plasma and urine samples, sample with ADN
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Real-time Continuous Glucose Monitoring on Glucose Control and Outcomes of Critically Ill Patients
Status: UNKNOWN
Conditions: Hyperglycemia
Interventions: OTHER: Different methods of blood glucose monitoring between groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of a Closed-loop System With Glucagon, Exercise and Mixed Meals
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Bi-hormonal closed loop pump|DEVICE: Standard opened loop pump|DEVICE: Insulin closed loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Galacto-oligosaccharides (GOS) on Faecal Gut Microbiota in Adult Women
Status: COMPLETED
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: GOS 1|DIETARY_SUPPLEMENT: GOS 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction
Status: COMPLETED
Conditions: Mild Hepatic Dysfunction|Moderate Hepatic Dysfunction
Interventions: DRUG: Fx-1006A|DRUG: Fx-1006A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of HS-10383 in Chinese Adult Subjects With Refractory or Unexplained Chronic Cough (RUCC)
Status: NOT_YET_RECRUITING
Conditions: Cough
Interventions: DRUG: HS-10383|DRUG: HS-10383 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metronidazole Drug Interaction Study With MMX® Mesalazine/Mesalamine
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metronidazole + MMX Mesalazine/mesalamine placebo|DRUG: Metronidazole + MMX Mesalazine/mesalamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare SH T00658ID Over Ortho Tri-Cyclen Lo (US/Canada)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Estradiol valerate, Dienogest (Natazia, Qlaira, BAY86-5027)|DRUG: Ortho Tri Cyclen Lo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of OM-85 on Respiratory Tract Infections and Adenoid Tissue in Children With Adenoid Hypertrophy
Status: UNKNOWN
Conditions: Adenoid Hypertrophy|Adenoid Hyperplasia|Respiratory Tract Infections|Preschool Children
Interventions: BIOLOGICAL: OM-85|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cost-utility Analysis, Cost-effectiveness Analysis, Budget Impact Analysis
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Systematic screening of AOMI by BPI measurement.|OTHER: Management of CVRF by a motivationnal interviewing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Pertussis|Whooping Cough
Interventions: BIOLOGICAL: Tetanus Toxoid, Diphtheria Toxoid and Pertussis Vaccine|BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed For Adult Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Expression of Programmed Death Ligand-1 (PD-L1) in Nasopharyngeal and Hyypopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal and Hypopharyngeal Carcinoma
Interventions: DIAGNOSTIC_TEST: immunohistochemical
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-Term Extension Study of AT2101 (Afegostat Tartrate) in Type 1 Gaucher Patients
Status: COMPLETED
Conditions: Gaucher Disease|Type 1 Gaucher Disease|Gaucher Disease, Type 1
Interventions: DRUG: afegostat tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Psilocybin|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Neutropenia|Thrombocytopenia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time
Status: COMPLETED
Conditions: Heart Transplantation|Kidney Transplantation|Liver Transplantation
Interventions: DRUG: Tacrolimus|DRUG: Tacrolimus prolonged release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Analgesic Study of Adductor Canal &IPACK Block With Liposomal Bupivacaine in Knee Arthroplasty
Status: RECRUITING
Conditions: Liposomal Bupivacaine|Postoperative Recovery|Unilateral Knee Arthroplasty
Interventions: OTHER: Nerve block with ropivacaine and intravenous analgesia|COMBINATION_PRODUCT: Nerve block with liposomal bupivacaine and intravenous analgesia|OTHER: Intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Farciminis and Hyperalgesia
Status: COMPLETED
Conditions: Inflammation|Pain
Interventions: DRUG: Lactobacillus farciminis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Kuvan in People With Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Kuvan|DRUG: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Digital Care Solution for Coronary Artery Disease Patients
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: A digital care solution for patients with Coronary Artery Disease|OTHER: Standard of care for patients with Coronary Artery Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Status: COMPLETED
Conditions: Hip Fracture|Myocardial Ischemia|Inflammation
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of OMA102 in the Treatment of Female Pattern Hair Loss
Status: NOT_YET_RECRUITING
Conditions: Female Pattern Baldness
Interventions: DRUG: OMA102|DRUG: OMA102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Endometrial Scratch Prior to Frozen Embryo Transfer in Patients With Recurrent Implantation Failure
Status: WITHDRAWN
Conditions: Recurrent Implantation Failure in Setting of Artifically Prepared Endometrium
Interventions: PROCEDURE: endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Advanced Improvement Program (ERAS) on Postoperative Outcomes in Patients Undergoing Open Heart Surgery
Status: UNKNOWN
Conditions: Enhanced Recovery After Surgery|Open Heart Surgery
Interventions: OTHER: ERAS (Enhanced Recovery After Surgery ) are evaluated|OTHER: ERAS are not evaluated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Embolectomy in Acute SYlvian Thrombosis in Refractory or Ineligible Patients to ALteplase
Status: TERMINATED
Conditions: Stroke, Acute
Interventions: OTHER: Hospitalization in specialized neuro-vascular unit|DRUG: Alteplase if patient is eligible|OTHER: Supportive care|PROCEDURE: Endovascular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Add-on Dextromethorphan in Bipolar Disorders
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Valproate|DRUG: Dextromethorphan 60 mg per day|DRUG: Placebo|DRUG: Dextromethorphan 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety in Recovering Opiate Dependence
Status: TERMINATED
Conditions: Generalized Anxiety Disorder|Comorbid Opiate Dependence in Remission|Status Post Methadone-Maintenance Treatment
Interventions: DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Clinical Trial to Evaluate the Safety, PK and PD of DA-5207 TDS in Healthy Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Aricept 5mg Tablet|DRUG: Aricept 10mg Tablet|DRUG: DA-5207 150mg|DRUG: DA-5207 170mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Saffron and Chamomile in the Management of Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Neurodegenerative Diseases
Interventions: OTHER: conventional therapy|DRUG: Saffron and Chamomile|DRUG: Crocin and Apigenin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Pain After Heart Surgery
Status: UNKNOWN
Conditions: Pain|Hyperalgesia|Chronic Illness|Neuropathic Pain
Interventions: DRUG: Pregabalin|DRUG: Ketamine infusion|DRUG: Placebo capsules|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
Status: NOT_YET_RECRUITING
Conditions: FHA (Functional Hypothalamic Amenorrhea)
Interventions: DRUG: Romosozumab|DRUG: Placebo|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Olmesartan medoxomil-hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Healing at Implants Installed in Sites Prepared Either With a Sonic Device or Drills
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: DEVICE: implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes
Status: COMPLETED
Conditions: Anxiety|Depression|Trauma|Behavior Problems
Interventions: BEHAVIORAL: Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems|OTHER: Monitoring and Feedback System|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of the Study Drugs Cediranib and Olaparib in Recurrent Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Fallopian Tube Carcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Ovarian Carcinoma|Ovarian High Grade Endometrioid Adenocarcinoma|Ovarian High Grade Serous Adenocarcinoma|Primary Peritoneal Carcinoma|Primary Peritoneal Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cediranib Maleate|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Olaparib|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux
Status: TERMINATED
Conditions: Laryngopharyngeal Reflux
Interventions: DRUG: Lansoprazole|DIETARY_SUPPLEMENT: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Erectile Dysfunction, Urinary Incontinence and Related QoL After TOOKAD® VTP for Low Risk Prostate Cancer
Status: TERMINATED
Conditions: Low Risk Prostate Cancer
Interventions: DRUG: TOOKAD VTP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt
Status: COMPLETED
Conditions: Coronary Arteriosclerosis|Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DEVICE: OrbusNeich Combo stent™|DEVICE: Everolimus Eluting Stent (EES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Standard-of-care Erythropoiesis-stimulating Agents on Forearm Blood Flow in Nondialysis-dependent Subjects With Anaemia Associated With Chronic Kidney Disease.
Status: COMPLETED
Conditions: Cardiovascular Diseases|Chronic Kidney Disease
Interventions: DRUG: Darbepoetin Alfa|DRUG: Acetylcholine|DRUG: Noradrenaline|DRUG: BQ 123
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study Evaluating Efficacy, Safety and Molecular Mechanism of Both N-acetylcysteine and Pentoxifylline Supplementation in Patients With Hepatic and Post Hepatic Jaundice
Status: RECRUITING
Conditions: Hepatic and Post Hepatic Jaundice
Interventions: DRUG: N-acetylcysteine|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Complications Related to Two Approaches of Ultrasonography-guided Subclavian Venous Catheterization
Status: COMPLETED
Conditions: Complication of Treatment|Catheterization
Interventions: PROCEDURE: Supra- vs Infraclavicular approach using ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, External-Beam Radiation Therapy, and Gemcitabine With or Without Brachytherapy Using Phosphorus P32 in Treating Patients With Locally or Regionally Advanced Unresectable Adenocarcinoma of the Pancreas
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|RADIATION: brachytherapy|RADIATION: phosphorus P32|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Non-phonatory Exercises in Patients With Unilateral Vocal Fold Paralysis Post-thyroidectomy
Status: RECRUITING
Conditions: Unilateral Vocal Cord Paralysis
Interventions: BEHAVIORAL: Non-phonatory exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study
Status: COMPLETED
Conditions: Symptomatic Carotid Stenosis|Hypercholesterolemia|Indication for Carotid Endarterectomy
Interventions: DRUG: Atorvastatin - Cholestyramine - Sitosterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults
Status: COMPLETED
Conditions: Food Allergy
Interventions: BIOLOGICAL: Low dose ADP101|BIOLOGICAL: High dose ADP101|BIOLOGICAL: Pooled Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Extension Study in Participants With Multiple Sclerosis Who Have Completed Study 205MS301 (NCT01064401) to Evaluate the Safety and Efficacy of BIIB019
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: BIIB019 (Daclizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tu Salud Si Cuenta Intervention in Increasing Physical Activity and Healthy Eating Among Latino Families
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|BEHAVIORAL: Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of One-handed and Two-handed Mask Ventilation Techniques on Global and Regional Lung Ventilation
Status: UNKNOWN
Conditions: Anesthesia
Interventions: OTHER: One-handed mask ventilation|OTHER: Two-handed mask ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors
Status: TERMINATED
Conditions: Gastrointestinal Tumors|Pancreatic Tumors|Gastrointestinal Neuroendocrine Tumors|Pancreatic Neuroendocrine Tumors
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablation of Arteries for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: COMBINATION_PRODUCT: Ablation Treatment|DIAGNOSTIC_TEST: Arterial Angiography Only|COMBINATION_PRODUCT: Single Arm non-Randomized Ablation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Dose Related Effects of Strawberry
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre-diabetes|Insulin Sensitivity|Insulin Resistance|Inflammation
Interventions: OTHER: freeze-dried whole strawberry powder 36 g powder|OTHER: freeze-dried whole strawberry powder 12 g|OTHER: freeze-dried control powder 0 g strawberry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neurofeedback Training in Adults With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Neurofeedback active|BEHAVIORAL: Neurofeedback sham|BEHAVIORAL: Metacognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Modes of Universal Adhesive in Smokers and Non-Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Participant
Interventions: DEVICE: G-Premio Bond in etch&rinse mode|DEVICE: G-Premio Bond in selective-etch mode|DEVICE: G-Premio Bond in self-etch mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship of Periodontitis and Cardiovascular Risk in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Periodontitis
Interventions: COMBINATION_PRODUCT: Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER