pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development and Initial Testing of a Couple-Based Intervention to Optimize Suicide and Self-Injury Treatment: COMPASS (Connecting, Overcoming, and Moving Past Suicide and Self-Injury)
Status: ACTIVE_NOT_RECRUITING
Conditions: Self-injurious Thoughts and Behaviours|Borderline Personality Disorder
Interventions: BEHAVIORAL: Sage (formerly known as COMPASS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of Immunomodulating Therapy With Donor-specific MSC in Pediatric Living-Donor Liver Transplantation
Status: UNKNOWN
Conditions: Pediatric Liver Transplantation
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: Cabotegravir (CAB) tablet|DRUG: Rilpivirine (RPV) tablet|DRUG: Cabotegravir - Injectable Suspension (CAB LA)|DRUG: Rilpivirine - Injectable Suspension (RPV LA)|DRUG: 2 NRTIs plus an INI, NNRTI, or PI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Center, Clinical Study to Evaluate the Safety of a New Personal Lubricant in Healthy Female Subjects
Status: COMPLETED
Conditions: Erythema|Edema
Interventions: DEVICE: Trojan "Chameleon" Personal Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells
Status: UNKNOWN
Conditions: Allergic Rhinitis|Rhinosinusitis Chronic
Interventions: BIOLOGICAL: Olfactory mucosa-derived mesenchymal stem cells|OTHER: Standard treatment of type Allergic Rhinitis according to the clinical protocols|OTHER: Standard treatment of type Chronic Polypous Rhinosinusitis according to the clinical protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibration Training in Chronic Obstructive Pulmonary Disease (COPD)-Patients During a Three-week Rehabilitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: whole body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Omics Technology to Explore the Mechanism of Acupuncture Treatment of Different Acupoints of Knee Osteoarthritis
Status: COMPLETED
Conditions: Acupuncture Therapy
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone as Salvage Therapy in Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Daratumumab-Hyaluronidase-Fihj@1,800 Mg-30,000 Unit/15 mL@SUBCUT@VIAL (ML)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Study of DRM01 in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Olumacostat Glasaretil|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASG-15ME is a Study of Escalating Doses of AGS15E Given as Monotherapy in Subjects With Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Metastatic Urothelial Cancer
Interventions: DRUG: AGS15E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT)
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Efficacy and Safety of Apalutamide as Neoadjuvant Endocrine Therapy in High-Risk and Oligometastatic Prostate Cancer
Status: RECRUITING
Conditions: High-Risk and Oligometastatic Prostate Cancer
Interventions: DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of Adacel® Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: Adacel® (Tetanus, Reduced Diphtheria Toxoid and Acellular Pertussis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Acne Scars With Fractional CO2 Laser Versus Radio-frequency Microneedling
Status: UNKNOWN
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DEVICE: Ablative fractional CO2 laser resurfacing/Radio-frequency microneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Communication Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Disease|Neoplasm Metastasis|Lung Neoplasm|Pulmonary Disease, Chronic Obstructive|Heart Failure, Congestive|Liver Cirrhosis|Kidney Failure, Chronic|Multiple Organ Failure|Health Care Quality, Access, and Evaluation|Intensive Care Units|Palliative Care, Health Services|Palliative Care, Patient Care|Lung Diseases|Cerebrovascular Disorders|Brain Injuries
Interventions: BEHAVIORAL: Facilitator-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abatacept and Cyclophosphamide Combination Therapy for Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis|Lupus Erythematosus, Systemic
Interventions: DRUG: abatacept|DRUG: cyclophosphamide|DRUG: azathioprine|DRUG: prednisone|DRUG: abatacept placebo|DRUG: azathioprine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone, an Antifibrotic and Antiinflammatory Drug
Status: COMPLETED
Conditions: Fibrosis|Hepatitis C Chronic
Interventions: DRUG: Pirfenidone|DRUG: Matched equivalent placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Anastrozole / Levonorgestrel (BAY98-7196)|DRUG: Gyno-Daktarin|DRUG: Sobelin vaginal creme|DRUG: Patentex oval|OTHER: Tampon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Wenzhou Gestational Diabetes Cohort
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus|Intrauterine Hyperglycemia|Birth Outcome, Adverse|Nutrition, Healthy
Interventions: OTHER: Standardized breakfast|OTHER: Standardized snack|OTHER: Standardized lunch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intralesional Versus Intramuscular Hepatitis B Vaccine Immunotherapy for Warts
Status: COMPLETED
Conditions: Intralesional Versus Intramuscular Hepatitis B Vaccine for Multiple Common Warts
Interventions: BIOLOGICAL: hepatitis B vaccine immunotherapy of common warts (GeneVac-B 10 ml vial, Serum Institute of India Ltd., Pune, India)|BIOLOGICAL: Intralesional saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rural China Electric Kettle Promotion Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Compliant Behavior|Diarrheal Disease|Pollution; Exposure
Interventions: BEHAVIORAL: Electric Kettle Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis.
Status: COMPLETED
Conditions: Hepatitis B|Cirrhosis
Interventions: DRUG: LdT (Telbivudine) and lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Follow-up of Doravirine/Islatravir (DOR/ISL 100 mg/0.75mg) for Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection (MK-8591A-033)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1 Infection
Interventions: DRUG: MK-8591A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vibration, Stretching, and Taping on Proprioception, Strength, and Function
Status: COMPLETED
Conditions: Stretch|Vibration; Disorder
Interventions: OTHER: Percussion Massage Therapy|OTHER: Kinesiotaping|OTHER: Dynamic stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of Intratumoral/Intralesional Administration of V938 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic or Recurrent Malignancies (V938-001)
Status: TERMINATED
Conditions: Neoplasm Metastasis
Interventions: DRUG: 200 mg of pembrolizumab|BIOLOGICAL: V938
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fully Closed-Loop Insulin Delivery in Abdominal Surgery (CLAB)
Status: COMPLETED
Conditions: Perioperative Hyperglycaemia|Insulin Therapy|Elective Surgery|Closed-Loop Glucose Control|Artificial Pancreas|Liver Diseases|Diabetes Mellitus, Type 2|Colon Disease|Gastric Disease|Pancreatic Disease
Interventions: DEVICE: CamAPS HX|DRUG: Standard insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whole Milk to Improve Muscle Health in Older Women
Status: COMPLETED
Conditions: Dairy Products|Muscle Protein Synthesis|Aging|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Whole Milk|DIETARY_SUPPLEMENT: Skim Milk|DIETARY_SUPPLEMENT: Almond Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluorouracil and Leucovorin and/or Levamisole After Surgery In Treating Patients With Dukes' B Or Dukes' C Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: levamisole hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: tafasitamab|DRUG: rituximab|DRUG: lenalidomide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Headache After Coil Embolization for Unruptured Intracranial Aneurysms
Status: COMPLETED
Conditions: Headache|Aneurysm|Endovascular Procedures
Interventions: PROCEDURE: non-stent assisted coiling|PROCEDURE: stent assisted coiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of CsA+AVA in the Treatment of NSAA in the Elderly
Status: RECRUITING
Conditions: Aplastic Anemia
Interventions: DRUG: Ciclosporin|DRUG: Avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome.
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Phelan-McDermid Syndrome
Interventions: DIETARY_SUPPLEMENT: Q10 Ubiquinol|DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Multi-Vitamin B complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Gastric Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gastric Cancer|Stage IIIC Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: alvocidib|DRUG: irinotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: DRUG: Vatiquinone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual-reality for Upper Limb Rehabilitation in People With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Upper limb/handwriting exercises in an immersive virtual reality setting (VR-training)|OTHER: Upper limb/handwriting exercises in a real setting (RS-training)|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Aplastic Anemia|Hypoplastic Myelodysplastic Syndrome
Interventions: DRUG: BL-8040|DRUG: horse anti-thymocyte globulin (hATG)|DRUG: Methylprednisolone|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EC-THP Versus TCbHP in HER2-positive Lymph Node Positive Early Breast Cancer
Status: RECRUITING
Conditions: HER2 Positive Early Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Epirubicin|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 0% N2O|DRUG: 10% N2O|DRUG: 20% N2O|DRUG: 30% N2O|DRUG: 40% N2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Anti-thymocyte globulin|DRUG: Myeloablative Busulfan|PROCEDURE: Mesenchymal stem cell transplantation|RADIATION: Total body irradiation|PROCEDURE: Bone marrow or umbilical cord blood (UCG) stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Tramadol Intraligamentary Injections
Status: COMPLETED
Conditions: Pulpitis
Interventions: DRUG: Tramadol hydrochloride|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Cardiovascular Disease in Kidney Disease (MaCK) Study
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiovascular Disease|Inflammation|Atherosclerosis|Aortic Stiffness
Interventions: PROCEDURE: MRI carotid|PROCEDURE: APWV|DRUG: Hydroxychloroquine|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Dual Serotonin Norepinephrine Reuptake Inhibitor Desvenlafaxine Succinate in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Desvenlafaxine succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pretreatment With Norethindrone Acetate Prior to Levonorgestrel IUS Insertion for Heavy Menstrual Bleeding
Status: UNKNOWN
Conditions: Heavy Menstrual Bleeding|Menorrhagia|Hypermenorrhea
Interventions: DRUG: Norethindrone acetate pretreatment|OTHER: No pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: chemotherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibratory Anesthesia in Trigger Finger Injections
Status: RECRUITING
Conditions: Trigger Finger|Pain|Anesthesia, Local
Interventions: DEVICE: Vibration Anesthesia Device by Blaine Labs|DRUG: Gebauers Ethyl Chloride 100% Topical Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"
Status: UNKNOWN
Conditions: Hernia of Abdominal Wall|Incisional Hernia
Interventions: PROCEDURE: BP selfstanding felt|PROCEDURE: PP mesh|PROCEDURE: BP intraperitoneal mesh|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inferior Vena Cava Sonography in Hemodialysis Patients and Quality of Life
Status: COMPLETED
Conditions: Hemodialysis Complication|End Stage Renal Disease
Interventions: DIAGNOSTIC_TEST: sonographic measurement of inferior vena cava diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide
Status: RECRUITING
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: Busulfan|DRUG: Alemtuzumab|DRUG: Cyclophosphamide|DRUG: Sirolimus|RADIATION: Total Body Irradiation|BIOLOGICAL: Allogeneic peripheral blood stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Sustainable Small-scale Egg Production on Maternal and Child Nutrition in Rural Zambia
Status: COMPLETED
Conditions: Malnutrition, Child|Malnutrition, Infant
Interventions: OTHER: Egg production
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: OTHER: functional rehabilitation nursing program|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Lymphoma|Myelodysplastic Syndromes|Chronic Lymphocytic Leukemia|Immune System Diseases
Interventions: DRUG: Cyclophosphamide|DRUG: Busulfan|DRUG: Fludarabine monophosphate|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|PROCEDURE: Allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
Status: COMPLETED
Conditions: Healthy Young Men|Healthy Young Women
Interventions: DIAGNOSTIC_TEST: Maximal incremental exercise test|DIAGNOSTIC_TEST: 30-min submaximal exercise test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nt-proBNP Guided Primary Prevention of CV Events in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Heart Failure|Coronary Artery Disease
Interventions: DRUG: Telmisartan, Bisoprolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Study to Evaluate Safety and Efficacy of Specific Immunotherapy With Modified Allergen Extracts
Status: UNKNOWN
Conditions: Allergic Rhinitis|Allergic Conjunctivitis
Interventions: BIOLOGICAL: modified allergen extract|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: IBI308|DRUG: paclitaxel/ irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety and Immunogenicity of Meningococcal Vaccine
Status: COMPLETED
Conditions: Meningococcal Infection, Group B
Interventions: BIOLOGICAL: 10 μg Group B Meningococcal 8570 HOPS-G NOMV Vaccine|BIOLOGICAL: 25 μg Group B Meningococcal 8570 HOPS-G NOMV Vaccine|BIOLOGICAL: 50 μg Group B Meningococcal 8570 HOPS-G NOMV Vaccine|BIOLOGICAL: 75 μg Group B Meningococcal 8570 HOPS-G NOMV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of Mitoxantrone and Etoposide Combined With Hydroxychloroquine, for Relapsed Acute Myelogenous Leukemia
Status: TERMINATED
Conditions: Leukemia, Acute Myelogenous
Interventions: DRUG: Hydroxychloroquine|DRUG: Mitoxantrone|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The 3-Dimensional Printed Guide in Endodontic Microsurgery
Status: COMPLETED
Conditions: Endodontic Disease|Endodontic Re-treatment Failure
Interventions: DEVICE: 3-D printed Guide|OTHER: Conventional Endodontic Micro-Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citicoline Treatment of Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Citicoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplementation for Recurrent Urinary Tract Infections in Women
Status: UNKNOWN
Conditions: Recurrent Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: WelTract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiparametric MRI Study of Endogenous Analgesia and Prediction the Efficacy of Migraine Pharmacological Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Doluxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of SU 011248 in Head And Neck Carcinoma
Status: TERMINATED
Conditions: Recurrent Disease|Squamous Cell Head and Neck Carcinoma|Palliative Treatment
Interventions: OTHER: biopsies|DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: DCR-MYC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom Assessment for Patients With Gastro-esophageal Reflux Disease Receiving Helicobacter Pylori Eradication
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: H pylori eradication|OTHER: H pylori eradication timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Combination Inhaler (FlutiForm HFA MDI 100/10 µg and 250/10 µg) Versus Fluticasone and Formoterol Administered Alone, and Placebo in Patients With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate/Formoterol fumarate 250/10|DRUG: Placebo|DRUG: Fluticasone propionate/Formoterol fumarate 100/10|DRUG: Fluticasone propionate 250|DRUG: Formoterol fumarate 10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum
Status: COMPLETED
Conditions: Pseudoxanthoma Elasticum
Interventions: DRUG: DS-1211b|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: senofilcon A C3|DEVICE: Dailies Total 1 Multifocal Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Customized Antibiotic Treatment Duration Among Hospitalized Patients With Moderately Severe Community-Acquired Pneumonia
Status: RECRUITING
Conditions: Community-Acquired Pneumonia
Interventions: OTHER: Stop antibiotic|DRUG: Continue the antimicrobial treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Scalpel vs. Monopolar Electrocautery for D2 Distal Gastric Carcinoma Surgery
Status: UNKNOWN
Conditions: Gastric Cancer|Surgery|Ultrasonic Scalpel|Monopolar Electrocautery|Operation Time|Blood Loss, Surgical|Quality of Life|External Causes of Morbidity and Mortality
Interventions: DEVICE: Monopolar electrocautery|DEVICE: Ultrasonic scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Transcranial Direct Current Stimulation Upon Sleep Spindles in Healthy Older Adults
Status: SUSPENDED
Conditions: Sleep|Aging|Healthy Aging
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Sexual Dysfunction|Sexuality and Reproductive Issues
Interventions: RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection
Status: COMPLETED
Conditions: Pancreatic Cancer|Esophageal Cancer|Gastric Cancer|Rectal Cancer|Hepatobiliary Cancer|Colon Cancer
Interventions: OTHER: Usual Care|OTHER: Perioperative Geriatrics Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of KRN125 in Patients With Multiple Myeloma and Malignant Lymphoma
Status: COMPLETED
Conditions: Multiple Myeloma and Malignant Lymphoma
Interventions: DRUG: KRN125(pegfilgrastim), PLR001(plerixafor)|DRUG: KRN8601(filgrastim), PLR001(plerixafor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning During Free Flap Reconstruction
Status: COMPLETED
Conditions: Remote Ischemic Preconditioning
Interventions: PROCEDURE: remote ischemic preconditioning (RIPC)|PROCEDURE: sham-RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propolis in Reducing Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Propolis 15%|OTHER: Propolis 10%|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Chloride and AKI in Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: 0.9% Normal Saline (0.9% Sodium Chloride) injection|DRUG: Isolyte S injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Decapeptyl SR 11.25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Standard Catheter-directed Thrombolysis Effectiveness in Intermediate-High-Risk Pulmonary Embolism Patients
Status: RECRUITING
Conditions: Pulmonary Embolism Acute
Interventions: COMBINATION_PRODUCT: Standard Catheter-Directed Low Dose Thrombolysis|DRUG: Standard Anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Aclidinium Bromide 400 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a Single Subcutaneous Dose of Epoetin Beta in Healthy Japanese and Caucasian Male Subjects
Status: COMPLETED
Conditions: Chronic Kidney Failure|Anaemia
Interventions: DRUG: Epoetin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Test if TEV-50717 is Safe and Effective in Relieving Abnormal Involuntary Movements in Cerebral Palsy
Status: TERMINATED
Conditions: Cerebral Palsy, Dyskinetic
Interventions: DRUG: TEV-50717
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Single Probiotic on Metabolic Control in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG (ATCC 53103)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: Remlarsen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Anticoagulant Use for Surgery Evaluation Study Part 2 Pilot
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: PAUSE Perioperative DOAC Management|OTHER: ASRA Perioperative DOAC Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Prophylaxis for Microbiome Modulation and VAP or Infections Prevention in Multitrauma Patients
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia|Infection|Trauma
Interventions: DIETARY_SUPPLEMENT: LactoLevure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Newly Formulated Tylenol Tablet (Acetaminophen) to the Tylenol 8 Hour (H) Extended Release (ER) Tablet (Acetaminophen) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia
Interventions: DRUG: Imetelstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: IDP-120 Gel|DRUG: IDP-120 Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Failure Worsens Muscle Strength in COPD
Status: COMPLETED
Conditions: COPD|CHF|Muscle Weakness
Interventions: DIAGNOSTIC_TEST: isokinetic dynamometer|DIAGNOSTIC_TEST: Cardiopulmonary Exercise Test|DIAGNOSTIC_TEST: Functional Capacity Tests|DIAGNOSTIC_TEST: Lung Function Test|DIAGNOSTIC_TEST: Doppler Echocardiography|DIAGNOSTIC_TEST: Anthropometry and Body Composition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trila of Sunitinib Schedule 4/2 vs. Shedule 2/1 as First Line Therapy in Metastatic Renal Cell Carcinoma.
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|Minority Stress|Mental Health Wellness 1
Interventions: BEHAVIORAL: Mindfulness-Based Queer Resilience (MBQR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma
Status: UNKNOWN
Conditions: Glioblastoma Multiforme of Brain|Anaplastic Astrocytoma of Brain
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are Offline Meals Healthy Meals? A Field Experiment to Promote Healthier Eating in Families
Status: RECRUITING
Conditions: Health Behavior|Smartphone Addiction|Healthy Nutrition
Interventions: BEHAVIORAL: Time out from smartphone use during meal time|BEHAVIORAL: Control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetic Cases
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Exenatide|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-548|DRUG: Moxifloxacin|DRUG: Moxifloxacin Placebo|DRUG: VX-548 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mussels, Inflammation and Rheumatoid Arthritis (MIRA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Blue mussel diet|OTHER: Meat/Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis
Status: COMPLETED
Conditions: Primary Biliary Cholangitis|Primary Biliary Cirrhosis|Cholangitis|Cholestasis|Biliary Tract Diseases|Bile Duct Stricture
Interventions: DRUG: HTD1801 (BUDCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Tolerability After Intravenous Administration of BIBN 4096 BS in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBN 4096 BS - in single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Cognitive Behavior Therapy for Insomnia for Parents Who Have Lost a Child
Status: COMPLETED
Conditions: Insomnia|Bereavement
Interventions: BEHAVIORAL: Therapist guided Internet-CBT for insomnia|OTHER: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome
Status: TERMINATED
Conditions: Guillain-Barre Syndrome
Interventions: DIAGNOSTIC_TEST: Peripheral nerve ultrasound|DIAGNOSTIC_TEST: Measurement of strength
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Lenalidomide, Melphalan and Dexamethasone in AL Amyloidosis
Status: COMPLETED
Conditions: Leukemia|Amyloidosis
Interventions: DRUG: Lenalidomide|DRUG: Melphalan|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ICT-107 Immunotherapy in Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: ICT-107|BIOLOGICAL: Placebo DC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Modified Approach for Morbid Obese With Gynecologic Cancer
Status: UNKNOWN
Conditions: Malignant Neoplasm of Cervix, Endometrium and Ovary
Interventions: PROCEDURE: Approach for cancer resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Intervention in Infants
Status: COMPLETED
Conditions: Vitamin D Status
Interventions: DIETARY_SUPPLEMENT: Vitamin D at 30 ug/day|DIETARY_SUPPLEMENT: Vitamin D at 10 ug/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.
Status: COMPLETED
Conditions: Altitude Hypoxia|Ventilation|Sleep|Oxidative Stress|Neurocognitive Dysfunction
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Inferiority Study to Compare the Effectiveness of the Seldinger Over-the-Wire Technique and the Modified Seldinger Technique
Status: COMPLETED
Conditions: Effectiveness and Safety of the Seldinger Wire Technique Using a 145 cm Guidewire With the Modified Seldinger Technique Using a 70 cm Guidewire
Interventions: DEVICE: Angiodynamic Bioflo Picc IR-KIT (145 cm guidewire) or|DEVICE: Angiodynamic Bioflo Picc MST-KIT (70 cm guidewire)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound on Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Chronic Pain|Osteoarthritis
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paired Integrative Home Exercise for Seniors With Dementia and Their Caregivers (PairedPLIE)
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease
Interventions: BEHAVIORAL: Paired PLIE Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria|Mass Drug Administration|Myanmar|Plasmodium Vivax|Primaquine
Interventions: DRUG: Focal Mass Drug Administration with Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ADalimumab in Persistent Early Oligoarthrits Study (ADEOS)
Status: COMPLETED
Conditions: Oligoarthritis
Interventions: DRUG: Adalimumab|DRUG: Methotrexate|DRUG: Placebo|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation in Individuals Temporomandibular Dysfunction With Bruxism
Status: COMPLETED
Conditions: Myofascial Pain|Temporomandibular Disorder|Bruxism
Interventions: PROCEDURE: Home Exercise Group|PROCEDURE: Telerehabilitation Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT