pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fluocinonide Cream in Treating Symptoms of Vaginal Dryness and Painful Sexual Intercourse In Patients With Breast Cancer Undergoing Hormone Therapy
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: DRUG: Fluocinonide Cream|PROCEDURE: Management of Therapy Complications|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sirolimus Coated Angioplasty Balloon in the Salvage of Thrombosed Arteriovenous Graft
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis|Arteriovenous Graft Occlusion
Interventions: DEVICE: Sirolimus Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retention of Potassium From Potatoes and Potassium Gluconate, and the Effect on Blood Pressure.
Status: UNKNOWN
Conditions: Hypertensive Disease
Interventions: DIETARY_SUPPLEMENT: Potassium control diet|DIETARY_SUPPLEMENT: Potassium gluconate diet|DIETARY_SUPPLEMENT: Potato Diet|DIETARY_SUPPLEMENT: French Fries Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Accelerated Intensity Modulated Radiation Therapy (AIMRT) to the Breast After Segmental Mastectomy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Accelerated intensity modulated radiation therapy (AIMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Status: RECRUITING
Conditions: Transthyretin Amyloidosis Polyneuropathy|Transthyrexin Amyloidosis Cardiomyopathy
Interventions: DRUG: YOLT-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Techniques of Nasogastric Tube Insertion Without Instrumentation
Status: COMPLETED
Conditions: General Anesthesia
Interventions: OTHER: Conventional technique|OTHER: Contralateral cricothyroid pressure|OTHER: Ipsilateral head turning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Low Intensity Focused Ultrasound to Modulate Deep Brain Areas for Tremor Control in Parkinson's Disease Patients.
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Low intensity focused ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase IIa Safety and Efficacy Study of SRD174 Cream in Patients With AD-associated Pruritus
Status: COMPLETED
Conditions: Pruritus, Atopic Dermatitis
Interventions: DRUG: SRD174 Cream|OTHER: vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Injection of Eye Muscles to Treat Strabismus
Status: UNKNOWN
Conditions: Strabismus|Esotropia|Exotropia|Graves Disease|Ptosis, Eyelid
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload
Status: TERMINATED
Conditions: Transfusional Iron Overload|Beta-Thalassemia
Interventions: DRUG: SPD602
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LL-BMT1 in Patients With Elevated Intraocular Pressure
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: LL-BMT1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Finerenone (Kerendia, BAY94-8862)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Pancreatic Polypeptide on Gastric Motor Function and Food Intake in Humans
Status: COMPLETED
Conditions: Hunger
Interventions: DRUG: 3 pmol/kg*min pancreatic polypeptide|DRUG: 10 pmol/kg*min pancreatic polypeptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Investigation of the Impact of Early Mobilization on the Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage.
Status: RECRUITING
Conditions: Early Ambulation|Standard of Care|Subarachnoid Hemorrhage, Aneurysmal
Interventions: BEHAVIORAL: Early mobilization protocol|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electrodessication, Potassium Titanyl Phosphate (KTP) Laser and Pulsed Dye Laser for Treatment of Cherry Angiomata
Status: COMPLETED
Conditions: Cherry Angioma
Interventions: PROCEDURE: Electrodessication|PROCEDURE: Pulsed dye laser (PDL)|PROCEDURE: potassium titanyl phosphate (KTP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension
Status: COMPLETED
Conditions: Anesthesia|Hypotension|Lung Ultrasound|Echocardiography|Perioperative Complication
Interventions: PROCEDURE: Ultrasound-based protocol based fluid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity of Hepatitis A Vaccine in Inflammatory Bowel Disease (IBD) Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis|Hepatitis A
Interventions: BIOLOGICAL: Epaxal Berna (virosomal hepatitis A vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Safety and Efficacy in MK-0954A Combination in Participants With Hypertension (MK-0954A-373 AM3)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Losartan 50 mg / HCTZ 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Cardiovascular Efficacy of Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD
Status: COMPLETED
Conditions: Chronic Hemodialysis (ESRD)
Interventions: DRUG: Hydralazine/Isorsorbide Dinitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Caring Connections: A Program to Alleviate Social Isolation and Loneliness in Individuals Living With Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries and Disorders (SCI/D)
Interventions: OTHER: Caring Connections|OTHER: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Tranexamic Acid on Uterine Blood Flow After Vaginal Delivery
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: 5% glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Healthy Volunteer Study to Establish the Bioequivalence of BG00012 Supplied by 2 Different Commercial Manufacturers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: dimethyl fumarate - Reference form|DRUG: dimethyl fumarate - Test form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness and Safety of Korean Herbal Medicine for Post-accident Syndromes After Acute Phase
Status: COMPLETED
Conditions: Traffic Accident|Whiplash Syndrome
Interventions: PROCEDURE: Korean herbal medicine treatment|PROCEDURE: Non-Korean herbal medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuro-Music Therapy for Recent Onset Tinnitus: Evaluation of a Therapy Concept
Status: UNKNOWN
Conditions: Tinnitus
Interventions: BEHAVIORAL: Neuro-Music Therapy immediately|BEHAVIORAL: Neuro-Music Therapy after waiting time|BEHAVIORAL: Music-therapeutical stress management coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program
Status: RECRUITING
Conditions: Body Weight|Body Weight Changes|Obesity|Overweight and Obesity|Overweight|Behavior, Eating|Physical Inactivity|Chronic Disease|Weight Loss|Weight Reduction
Interventions: BEHAVIORAL: Together, Eating and Activity, Matter Plus (TEAM+) Online|BEHAVIORAL: Together, Eating and Activity, Matter Plus (TEAM+) In-Person
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The OCT SORT-OUT VIII Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Angina Pectoris|Myocardial Infarction
Interventions: DEVICE: Everolimus eluting bioresorbable polymer stent|DEVICE: Biolimus eluting bioresorbable polymer stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients
Status: COMPLETED
Conditions: Critically Ill|Post Intensive Care Syndrome
Interventions: DIAGNOSTIC_TEST: Therapeutic Vibration Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect Of Applied Neuromuscular Electrical Stimulation In Addition To Lumber Stabilization Exercises On The Multifidus Muscle Thickness
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: exercises|OTHER: neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bile Acid Secretion and Sequestration on GLP-1 Secretion
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sevelamer|DRUG: Cholecystokinin|DRUG: Sevelamer placebo|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of High PCO2 Solution on Esophageal Acid Sensation
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: 24-Hr Esohpageal pH Monitoring|PROCEDURE: PCO2 Acid Perfusion and 0.1N HCI Perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Colloid Versus Crystalloid on Coagulation
Status: UNKNOWN
Conditions: Bloodloss
Interventions: DRUG: Ringer-lactate "SAD"|DRUG: HES 130/04
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type
Status: WITHDRAWN
Conditions: Astrocytoma, Grade IV|Glioblastoma|Giant Cell Glioblastoma|Glioblastoma Multiforme
Interventions: BIOLOGICAL: CYNK-001 systemic and Intra cavity administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Platelet Activation and Inflammatory Response of Platelets in Hematopoietic Stem Cell Allograft Patients Post-transplant: Spontaneously and After Stimulation by an CMV Antigen
Status: COMPLETED
Conditions: Allograft
Interventions: OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase III Clinical Trial of DA-5212 in Patients With Functional Dyspepsia
Status: NOT_YET_RECRUITING
Conditions: Functional Dyspepsia
Interventions: DRUG: DA-5212|DRUG: DA-5212-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunonutrition in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Nutrition supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Imaging of the Therapeutic Effect of Pregabalin in Treatment for Neuropathic Pain
Status: UNKNOWN
Conditions: Diabetic Neuropathies|Pain
Interventions: OTHER: MR Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|BIOLOGICAL: Amnion membrane|DRUG: Taurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proportional Dose of Sublingual Fentanyl Tablet Based on Daily Opioid Requirement
Status: WITHDRAWN
Conditions: Cancer Pain|Breakthrough Pain
Interventions: DRUG: Intravenous Infusion|DRUG: Sublingual Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Morbidity and Mortality After Gastric Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Siewert Type III Adenocarcinoma of Esophagogastric Junction|Stomach Cancer
Interventions: PROCEDURE: Elective Surgery for gastric cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin and Systemic Inflammation in HIV
Status: UNKNOWN
Conditions: PreDiabetes|HIV-1-infection
Interventions: DRUG: Metformin Hydrochloride 850 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Psychological Disorders After Immediate Postpartum Hemorrhage
Status: UNKNOWN
Conditions: Postpartum Hemorrhage|Postpartum Women|Postpartum Depression|Postpartum Stress|Postpartum Anxiety
Interventions: BEHAVIORAL: • The Edinburgh postnatal depression scale (EPDS), validated in French, with a discrimination threshold ≥ 11.|BEHAVIORAL: The GAD-7 with a discrimination threshold ≥10.|BEHAVIORAL: • Spielberger's State-Trait anxiety inventory, Form Y (validated in French), with a STAI (form Y-A) discrimination threshold ≥ 46|BEHAVIORAL: The IES-R, validated in French, with a discrimination threshold ≥ 30.|BEHAVIORAL: EPDS, MINI, STAI-A and B, IES-R and QEVA (experience)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Head-to-head Comparison of [18F]F-PSMA-N5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
Status: RECRUITING
Conditions: Prostate Cancer|PET/CT
Interventions: DRUG: [18F]F-PSMA-N5|DRUG: [68Ga]Ga-PSMA-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: REGN9933|DRUG: Enoxaparin|DRUG: Apixiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparable Study of Different Radiation Dose in Esophageal Carcinoma
Status: UNKNOWN
Conditions: Esophageal Carcinoma
Interventions: RADIATION: intensity modulated radiation therapy in both arms|DRUG: concurrent chemotherapy with radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 Specific Antibody Responses
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: DIAGNOSTIC_TEST: blood draw|DIAGNOSTIC_TEST: fingertip tests for POC assays|DIAGNOSTIC_TEST: saliva collection|DIAGNOSTIC_TEST: collection of swabs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness Intervention in Reducing Anxiety in Patients Who Have Been Treated for Gynecologic Cancer
Status: COMPLETED
Conditions: Anxiety|Cancer Survivor|Cognitive Impairment|Depression|Distress|Fatigue|Malignant Female Reproductive System Neoplasm|Pain|Sexual Dysfunction
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Nurse-led Telephone Based Service for Early Palliative Care (PALTEL)
Status: NOT_YET_RECRUITING
Conditions: Palliative Care|Cancer
Interventions: OTHER: Nurse-led telephonic calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts
Status: COMPLETED
Conditions: Coronary Artery Disease|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aspirin 100 mg|DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain
Status: COMPLETED
Conditions: Trigeminal Neuralgia|Tic Douloureux
Interventions: DEVICE: Low Intensity Low Frequency Surface Acoustic Wave Ultrasound (PainShield™)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pistachios Blood Sugar Control, Heart and Gut Health
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Diseases
Interventions: DRUG: Pistachio|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating ACUVUE® Abiliti™ 1-Day Soft Therapeutic Lenses for Myopia Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE® Abiliti™ 1-Day Soft Therapeutic Lenses for Myopia Management (A1D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of BIIB074 in Neuropathic Pain From Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Lumbosacral Radiculopathy
Interventions: DRUG: BIIB074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canderel:Effects on Blood Glucose Concentration and Appetite Scores
Status: UNKNOWN
Conditions: Appetitive Behavior|Glucose Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Canderel drink|DIETARY_SUPPLEMENT: Canderel+Lyle's Golden Syrup drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Effect of Estrogen on Estrogen Receptor Biomarkers in Healthy Postmenopausal Women (0000-094)(COMPLETED)
Status: COMPLETED
Conditions: Postmenopause
Interventions: DRUG: Comparator: placebo|DRUG: Comparator: Estrace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Trial of Pregnenolone in Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Autism
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The REgistry of Very Early Estrogen and AnovuLation
Status: RECRUITING
Conditions: Hypothalamic Amenorrhea, Functional|Hypothalamic Amenorrhea|Functional Hypogonadotropic Hypogonadism
Interventions: OTHER: Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24)|OTHER: REVEAL Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance of Bioceramic vs High Viscosity GIC for Cervical Restorations of Geriatric Patients
Status: RECRUITING
Conditions: Cervical Caries
Interventions: OTHER: Bioceramic glass ionomer restoration|OTHER: Resin modified glass ionomer restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma
Status: WITHDRAWN
Conditions: Melanoma|Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma
Interventions: DRUG: sorafenib tosylate|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation for Whiplash Associated Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Whiplash Injury of Cervical Spine
Interventions: OTHER: Manual therapy|DEVICE: Telehealth exercises|OTHER: Non-computer based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (18F-Fluciclovine PET-CT) for the Measurement of Therapeutic Response in Patients With Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Fluciclovine F18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Hospice|Psilocybin|Demoralization|Terminal Illness|Cancer-related Problem/Condition|Psychotherapy|Terminal Cancer|Cancer Terminal
Interventions: DRUG: Psilocybin|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fear of MOVEment After MI and AF - InterneT Patient Education
Status: RECRUITING
Conditions: Myocardial Infarction|Atrial Fibrillation|Kinesiophobia
Interventions: BEHAVIORAL: Digital patient education to reduce kinesiophobia after MI and/or AF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Capecitabine, Paclitaxel, and Trastuzumab in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: capecitabine|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC
Status: RECRUITING
Conditions: Liver Cirrhosis|Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: Elecsys® GAAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCT
Status: COMPLETED
Conditions: Graft vs Host Disease|Graft Versus Host Disease|Hematopoietic Stem Cell Transplantation|Peripheral Blood Stem Cell Transplantation
Interventions: OTHER: Questionnaires|OTHER: Blood Sample|OTHER: Stool Sample|OTHER: Clinical data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria
Status: COMPLETED
Conditions: Neonatal Respiratory Distress Related Conditions|Neonatal Respiratory Failure|Prematurity|Oxygen Toxicity
Interventions: DEVICE: OxyMate|OTHER: Manual oxygen control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Microfluidic Noodle on Blood Glucose Levels of Healthy Volunteers.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Microfludic noodle|OTHER: Control noodle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of the 2015-2016 Formulation of Fluzone® Quadrivalent (Influenza Vaccine) Among Healthy Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone® Quadrivalent Influenza Vaccine, No Preservative|BIOLOGICAL: Fluzone® Quadrivalent Influenza Vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety of Treatment of Uterine Fibroids With Asoprisnil
Status: COMPLETED
Conditions: Fibroid Uterus|Leiomyoma|Menorrhagia|Metrorrhagia|Uterine Fibroids
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Availability of Oral Primaquine and Its Inert Metabolite, Carboxyprimaquine, in the Body
Status: WITHDRAWN
Conditions: Healthy|Pharmacokinetic
Interventions: DRUG: Regimen 1 (Oral primaquine)|DRUG: Regimen 2 (IV primaquine phosphate)|DRUG: Regimen 3 (IV carboxyprimaquine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: At-risk and vulNerable Individuals To Infection With COVID-19 and ProActive inTervention With intEgrated Health and Social Care
Status: RECRUITING
Conditions: Emotional Distress|Quality of Life|Mental Health
Interventions: OTHER: System Navigator|OTHER: Tailored list of resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective Study Of Free-Hand Transperineal Image Fusion Targeted Biopsies Under Local Anesthesia
Status: COMPLETED
Conditions: Prostate Neoplasm
Interventions: PROCEDURE: Standard prostate biopsy|PROCEDURE: Targeted and standard prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing At-Home Mobile Spirometry to In-Clinic in Moderate Asthma Participants Taking Long-Acting Beta Agonist
Status: COMPLETED
Conditions: Moderate Asthma
Interventions: DRUG: Long-Acting Beta Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Inter and Intra Reliability of Cardiopulmonary Exercise Testing in Abdominal Aortic Aneurysm Patients
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: OTHER: Observer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-invasive Carbon Dioxide Monitoring and Endoscopic Retrograde Cholangiopancreatography Patients
Status: UNKNOWN
Conditions: Patient Monitoring
Interventions: DRUG: propofol (2 mg/kg) and fentanyl (1ug/kg) and 4 liters O2 flow through nasal cannula
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PHILOS Augmented - a Multicenter Randomized Controlled Trial
Status: COMPLETED
Conditions: Humerus Fractures|Closed Fracture of the Proximal Humerus
Interventions: DEVICE: PHILOS+|DEVICE: PHILOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity
Status: NOT_YET_RECRUITING
Conditions: Liver Steatosis|MASH|MASLD
Interventions: BEHAVIORAL: Telehealth coaching for liver disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Intracellular Content From Lactobacillus Casei CRL-431 on Antioxidant Capacity of Breast Milk
Status: COMPLETED
Conditions: Mothers|Lactation
Interventions: DIETARY_SUPPLEMENT: Postibiotic formulation|DIETARY_SUPPLEMENT: Placebo formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Cancer Side-effects With Systematic Light Exposure
Status: COMPLETED
Conditions: Cancer-related Fatigue|Cancer-related Cognitive Impairment
Interventions: DEVICE: Litebook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Apalutamide in Chinese Participants With Non Metastatic Castration Resistant Prostate Cancer (NM-CRPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: Placebo|DRUG: Androgen-deprivation Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of 212Pb-Pentixather Radioligand Therapy
Status: NOT_YET_RECRUITING
Conditions: Carcinoid Tumor Lung|Neuroendocrine Tumor of the Lung|Carcinoma, Small-Cell Lung
Interventions: DRUG: 212-Lead Pentixather|DIAGNOSTIC_TEST: 203-Lead Pentixather SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of a System for the Anticipation of Challenging Behaviors
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Smart, non-invasive shirt - Physiological parameters|OTHER: Smart, non-invasive shirt - Relation with challenging behaviors|OTHER: Smart, non-invasive shirt - Proof of Concept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: H - Test Usage in Identification of Sexual Orientation Among People.
Status: COMPLETED
Conditions: Sexual Behavior|Sexual Orientation Conflict Disorder|Sexual Arousal Disorder|Sexual Orientation|Sexual; Orientation, Relationship Disorder
Interventions: DIAGNOSTIC_TEST: H - Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Characterization of Changes in Ventricular Mechanics in Response to Lexiscan Stress Using Tagged Cine Cardiac Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Posaconazole and Voriconazole on the Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine
Status: COMPLETED
Conditions: Pharmacokinetics and Pharmacodynamics of Sublingual Buprenorphine
Interventions: DRUG: Placebo|DRUG: vorikonazole|DRUG: posakonazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: SK&F-105517-D 10 mg capsule|DRUG: Carvedilol-immediate release (IR) 2.5 mg tablet|DRUG: SK&F-105517-D 20 mg capsule|DRUG: SK&F-105517-D 40 mg capsule|DRUG: Carvedilol-IR 10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Pembrolizumab in Well Differentiated G3 Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Well-Differentiated Neuroendocrine Carcinoma|High Grade Neuroendocrine Carcinoma, Any Site
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab|DRUG: Hyperpolarized 13C-Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rimonabant in Abdominally Obese Patients With Impaired Fasting Blood Glucose
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: Rimonabant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Procedure With Socio-aesthetic Care on Anxiety and Pain Scale in the Early Rest of Pulmonary Transplant.
Status: COMPLETED
Conditions: Pulmonary Transplant
Interventions: OTHER: Comfort Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrospective Observational Comparison Study Between Ustekinumab and Tofacitinib as Third Line Therapy in a Multicenter Cohort of Patients With Refractory Ulcerative Colitis.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Ustekinumab|DRUG: Tofacitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Depressive Disorder|Schizophrenia|Schizoaffective Disorder|Obsessive-Compulsive Disorder
Interventions: DEVICE: Magnetic Seizure Therapy (MagPro MST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pulmonary Vascular Reactivity Test in Patients With Pulmonary Arterial Hypertension and a Cardiac Shunt
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension With Congenital Cardiac Shunt
Interventions: OTHER: Pharmacological test of pulmonary endothelial
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Imatinib Mesylate and Bevacizumab in Treating Patients With Advanced Melanoma or Other Advanced Cancers
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage III Melanoma|Stage IV Melanoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: imatinib mesylate|BIOLOGICAL: bevacizumab|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maple Products and Cognitive Performance During High Intensity Intermittent Exercise (HIIE)
Status: COMPLETED
Conditions: Carbohydrate Ingestion|Cognitive Performance|High Intensity Interval Training
Interventions: DIETARY_SUPPLEMENT: Solution ingestion|BEHAVIORAL: Cognitive flexibility|PROCEDURE: Brain oxygenation|OTHER: Palatability|PROCEDURE: Blood glucose|BEHAVIORAL: Perceived exertion|BEHAVIORAL: High Intensity Interval Training bouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess Usability of Risankizumab Autoinjector Combination Product in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Risankizumab|DEVICE: Autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OKS for the Treatment of Hemispatial Neglect
Status: WITHDRAWN
Conditions: Neglect, Hemispatial|Neglect, Sensory|Neglect, Hemisensory
Interventions: DEVICE: OKS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Two Methods of Obtaining Tissue for Diagnosis of Sarcoidosis Namely the Conventional Method or the Ultrasound Guided Method
Status: UNKNOWN
Conditions: Sarcoidosis
Interventions: OTHER: cTBNA without ROSE|OTHER: cTBNA with ROSE|OTHER: EBUS-TBNA without ROSE|OTHER: EBUS-TBNA with ROSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: TBI (Traumatic Brain Injury)
Interventions: DEVICE: Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lidocaine Spray and Paracervical Block Application for Pain Relief During First-trimester Surgical Abortion: a Randomized, Double-blind, Placebo-controlled Trial
Status: COMPLETED
Conditions: Pain Score
Interventions: DRUG: Paracervical block|DRUG: Lidocaine spray|DRUG: Paracervical block + lidocaine spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Down Syndrome
Interventions: DEVICE: Inspire® Upper Airway Simulation System (Model 3028 IPG )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia
Status: COMPLETED
Conditions: Hyperphosphatemia|Chronic Kidney Disease
Interventions: OTHER: FOSTRAP Chewing Gum|OTHER: FOSTRAP Chewing Gum|OTHER: FOSTRAP Chewing Gum|OTHER: FOSTRAP Chewing Gum|OTHER: Placebo chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Functional Electrical Stimulation for Upper-limb Rehabilitation After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Functional Electrical Stimulation (FES)|DEVICE: Combination of Transcranial direct brain stimulation (tDCS) and FES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: a Comparison Between the Effects of Crystalloids and Colloids on Lung Ultrasound
Status: UNKNOWN
Conditions: Pulmonary Edema
Interventions: DRUG: hydroxyethyl starch in sodium chloride injection Brand Name: Voluven|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bisantrene for Relapsed /Refractory AML
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Allogeneic Stem Cell Transplantation
Interventions: DRUG: Bisantrene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Relationship Between Use of Albuterol Multidose Dry Powder Inhaler With an eModule (eMDPI) and Exacerbations in Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression.
Status: WITHDRAWN
Conditions: Depressive Disorder
Interventions: DEVICE: Magnetic seizure therapy|DEVICE: Electroconvulsive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Yaq-001 in Patients With Non-Alcoholic Steatohepatitis
Status: WITHDRAWN
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DEVICE: Yaq-001|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Comparative Assessment of Alveolar Bone Augmentation Using GUIDOR® Membrane in the Bound Edentulous Space
Status: TERMINATED
Conditions: Bone Regeneration
Interventions: DEVICE: GUIDOR® membrane with FDBA|DEVICE: GUIDOR® membrane|DEVICE: Bio-Gide® membrane with FDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge Study
Status: COMPLETED
Conditions: Typhoid Fever|Paratyphoid Fever
Interventions: BIOLOGICAL: Salmonella Typhi|BIOLOGICAL: Salmonella Paratyphi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of G001 in Patients With Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: G001 Topical Gel|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Combination Product (sumatriptan succinate / naproxen sodium)|DRUG: RELPAX(eletriptan) 40mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Homelessness
Interventions: DRUG: Nicotine Patches|BEHAVIORAL: mobile contingency management (mCM)|BEHAVIORAL: Smoking cessation counseling|DRUG: Nicotine rescue method|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Predictive Factors in the Reversibility or the Aggravation in the Disorders of the Glucose Metabolism in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Diabetes in Cystic Fibrosis Patients
Interventions: OTHER: Prospective cohort with an annual follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TTAX03 for the Treatment of Lumbosacral Facet Joint Pain
Status: NOT_YET_RECRUITING
Conditions: Facet Joint Pain
Interventions: BIOLOGICAL: TTAX03 10mg|BIOLOGICAL: TTAX03 25mg|BIOLOGICAL: Placebo Comparator: Control Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure Chemotherapy-related Nausea Vomiting in Children
Status: COMPLETED
Conditions: Pediatric Cancer|Nausea With Vomiting Chemotherapy-Induced
Interventions: BEHAVIORAL: manuel acupressure|BEHAVIORAL: sea-band acupressure|BEHAVIORAL: placebo manuel acupressure|BEHAVIORAL: placebo sea-band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE