pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Multicentre International STudy for the Prevention With Ialuril® of Radio-induced Cystitis (MISTIC)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: COMBINATION_PRODUCT: Radiotherapy+IAluril®+Ialuril Soft Gels®|RADIATION: Radiotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Postoperative Prolonged Sedation With Dexmedetomidine After Successful Reperfusion With EVT on Long-term Prognosis in Patients With AIS (PPDET)
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Dexmedetomidine prolonged sedation|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Project JAY HAP Registration Study
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: DEVICE: SS Bipolar Head + SL-TWIN Stem|DEVICE: Bipolar Head + SL-PLUS Stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Performance Status Assessment in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Status: TERMINATED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: BEHAVIORAL: Behavioral Assessment|OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Relationship Among Electroencephalography,Skin Conductance Response,Heart Rate Variability and Mental Health Among Smartphone Users After Receiving Texting or Calling
Status: COMPLETED
Conditions: Smartphone Users, Smartphone Addiction, Anxiety, and Skin Conductance
Interventions: DEVICE: social media stimuli (Line app)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Assessment of Coronary Flow Reserve by PET-H215O and FFR. Comparison With Dynamic Acquisition Using CZT Camera
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: OTHER: ASSESSMENT OF CORONARY FLOW RESERVE BY PET-H215O AND FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dermacyd PH_DETINLYN (Lactic Acid) Tangerine Mix - Compatibility
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINLYN (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Initialization of Methadone in Primary Care, Randomized Intervention Research for Preventing HCV Transmission Practices
Status: COMPLETED
Conditions: Hepatitis C|Substance Dependence|Methadone
Interventions: DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double-blind, Placebo-controlled, Phase I Dose-escalation Study of Single Dose GHB01L1 in Healthy Volunteers
Status: COMPLETED
Conditions: Seasonal Human Influenza
Interventions: BIOLOGICAL: GHB01L1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Ranging Study of AVI-4658 to Induce Dystrophin Expression in Selected Duchenne Muscular Dystrophy (DMD) Patients
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: AVI-4658 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Spanish Cognitive Intervention Program for Spanish-Speaking Latino/Hispanic Subarachnoid Hemorrhage Patients
Status: WITHDRAWN
Conditions: Subarachnoid Hemorrhage|Cognitive Impairment|Quality of Life|Depression, Anxiety
Interventions: DEVICE: brainHQ by Posit Science
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Milnacipran Added to Pregabalin for Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: No Treatment Added|DRUG: Milnacipran Added
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Interaction Between JNJ-64155806 and Ethinylestradiol/Drospirenone in Healthy Females
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: JNJ-64155806 150 mg|DRUG: Ethinylestradiol/drospirenone 0.02 mg/3 mg|DRUG: COCP Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection in Neck Muscles in Cervicogenic Headache
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: DRUG: Botulinum toxin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery
Status: COMPLETED
Conditions: Arrythmia
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine and propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Omarigliptin|DRUG: Sitagliptin|DRUG: Placebo to omarigliptin|DRUG: Placebo to Sitagliptin|DRUG: Open-label Metformin|DRUG: Open-label Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deferoxamine for Sickle Cell Chronic Leg Ulcer Treatment
Status: WITHDRAWN
Conditions: Chronic Cutaneous Ulcer|Sickle Cell Disease
Interventions: DRUG: Deferoxamine Product|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optic Nerve Sheath Diameter in Preeclampsia
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: Optic nerve sheath diameter measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Compression Therapy for Leg Ulcers and Kaposi Sarcoma in Western Kenya
Status: COMPLETED
Conditions: Chronic Leg Ulcer|Kaposi Sarcoma|HIV/AIDS and Infections
Interventions: OTHER: Locally sourced compression therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intranasal Dexmedetomidine
Status: UNKNOWN
Conditions: Safety and Efficacy of Intranasal Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam Hydrochloride|DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Acute Uncomplicated UTIs in Adults by Community Pharmacists
Status: UNKNOWN
Conditions: Urinary Tract Infections|Urinary Tract Infection Lower Acute
Interventions: OTHER: Educational training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Safety and Performance of the HARMONI® Toric Lens
Status: COMPLETED
Conditions: Aphakia|Corneal Astigmatism|Cataract
Interventions: DEVICE: HARMONI® Modular Toric Intraocular Lens|PROCEDURE: Cataract extraction with intraocular lens (IOL) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome of Extracorporeal Shock Wave Therapy in Patient With Axillary Web Syndrome
Status: UNKNOWN
Conditions: Axillary Web Syndrome|Breast Cancer|Lymphedema|Extracorporeal Shock Wave Therapy
Interventions: DEVICE: Low energy ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glenosphere Size and Scapular Notch in RSA, Prospective Randomized Study
Status: COMPLETED
Conditions: Total Shoulder Arthroplasty
Interventions: DEVICE: reverse shoulder arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: CV0701 Bivalent High dose|BIOLOGICAL: CV0701 Bivalent Medium dose|BIOLOGICAL: CV0701 Bivalent Low dose|BIOLOGICAL: CV0601 Monovalent High dose|BIOLOGICAL: Control vaccine|BIOLOGICAL: CV0801 Monovalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mental Stress & Diesel Exhaust on Cardiovascular Health
Status: UNKNOWN
Conditions: Blood Pressure|Inflammation|Catecholamines
Interventions: BEHAVIORAL: Trier social stress test|OTHER: Diesel exhaust
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Low Back Pain|Myofascial Pain Syndrome Lower Back
Interventions: DRUG: Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below.|DRUG: Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below.|DRUG: Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LOVE Trial: Limits On Vaginal Intercourse After Mid-urEthral Sling
Status: ACTIVE_NOT_RECRUITING
Conditions: Patient Satisfaction|Female Sexual Dysfunction
Interventions: BEHAVIORAL: Early restriction release|BEHAVIORAL: Standard restriction recommendation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Toripalimab or Combining With Temozolomide（iv） in the Treatment of Advanced/Metastatic Malignant Melanoma
Status: RECRUITING
Conditions: Malignant Melanoma
Interventions: DRUG: toripalimab|DRUG: Temozolomide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: Rostafuroxin|DRUG: Rostafuroxin|DRUG: Rostafuroxin|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontal Pocket|Periodontal Attachment Loss|Periodontal Inflammation
Interventions: OTHER: Thyme honey mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Time to the First Rescue Analgesic Among Parturients Receiving Intrathecal Additive Fentanyl or Intrathecal Fentanyl With TAP Block or TAP Block Alone for Elective Cesarean Sections Under Hyperbaric Bupivacaine Spinal Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain|Cesarean Section
Interventions: DRUG: Fentanyl HCl|DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French Anti-cancer Center at the End of the Containment Period of the SARS-CoV-2 Pandemic
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Brilacidin in Hospitalized Participants With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Brilacidin|DRUG: Placebo|DRUG: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Romidepsin Maintenance After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Cutaneous T-cell Lymphoma|T-Prolymphocytic Leukemia|T-Large Granulocytic Leukemia|T-Lymphoblastic Leukemia/Lymphoma|Peripheral T-Cell Lymphoma
Interventions: DRUG: Romidepsin|DRUG: Busulfan|DRUG: Fludarabine|PROCEDURE: Stem Cell Transplant|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Auxora in Patients with AKI and Injurious Lung "Crosstalk"
Status: RECRUITING
Conditions: Acute Kidney Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Interventions: DRUG: rimegepant 75 mg ODT|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tahneek on Hypoglycemia in Newborn Infants
Status: COMPLETED
Conditions: Neonatal Hypoglycemia|Infant, Small for Gestational Age|Macrosomia, Fetal|Intrauterine Growth Restriction|Premature Infant|Neonatal; Hypoglycemia, Diabetes, Maternal
Interventions: OTHER: Tahneek
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fasting Bioequivalence Study of Nisoldipine Extended-Release Tablets 40 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Albuterol Sulfate Extended-Release Tablets 8 mg|DRUG: VoSpire® ER Tablets 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study)
Status: COMPLETED
Conditions: Invasive Pulmonary Aspergillosis
Interventions: DRUG: Amphotericin B Liposomal 50 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Depression|Myocardial Infarction|Unstable Angina|STEMI|NSTEMI - Non-ST Segment Elevation MI
Interventions: OTHER: MBCT intervention for ACS patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactose-free Dairy Products on Athletes With Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Lactose free probiotic yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Determination of the Levels of Lipocalin-2 and Semaphorin3A
Status: COMPLETED
Conditions: Gingivitis|Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: Non-surgical Periodontal Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Kinetics, Efficacy and Safety of IVIG-L in Hypogammaglobulinemia Patients
Status: COMPLETED
Conditions: Hypogammaglobulinemia
Interventions: DRUG: IVIG-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Periodontal Treatment With Coenzyme Q10 in Association With Probiotics for Pregnant Women
Status: ENROLLING_BY_INVITATION
Conditions: Periodontal Diseases|Pregnancy Related
Interventions: OTHER: Probiotic Treatment|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Clinical Pilates and Whole Body Vibration Exercises in Postmenopausal Osteoporotic Women
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: OTHER: Clinical pilates|OTHER: Whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Autologous Adipose-derived Stem Cells in the Treatment of Knee Cartilage Injury
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Cartilage Degeneration
Interventions: OTHER: Autologous Adipose-derived Mesenchymal Stem Cell Gel|DRUG: Sodium Hyaluronate|PROCEDURE: Extraction of abdominal fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reminder Emails to Improve Pneumococcal Vaccine Completion at 12 Months of Age
Status: RECRUITING
Conditions: Pneumococcal Vaccines|Immunization Coverage
Interventions: OTHER: Enhanced reminders|OTHER: Standard CANImmunize notifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients
Status: COMPLETED
Conditions: Liver Transplant Recipient
Interventions: DRUG: Tacrolimus (reduced tacrolimus)|DRUG: Everolimus (reduced tacrolimus)|DRUG: Tacrolimus (tacrolimus elimination)|DRUG: Everolimus (tacrolimus elimination)|DRUG: Tacrolimus (tacrolimus control)|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium Carbonate|DRUG: Sertraline|DRUG: Nortriptyline|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Advanced Cancer
Interventions: RADIATION: Radium-223|RADIATION: 177Lu-DOTATATE|RADIATION: 177Lu-PSMA-617
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glivec® (Imatinib Mesylate, STI571) in Monotherapy Versus Glivec®-Interferon Alpha in the Treatment of Chronic-Phase Chronic Myeloid Leukaemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukaemia
Interventions: DRUG: Glivec|DRUG: Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boussignac Valve and Fibroptic Intubation in Morbidly Obese Patients, Can it be a Solution?
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DEVICE: Fibroptic intubation through Boussignac valve opening|DEVICE: Classic Fibroptic intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of High Flow Nasal Cannula During Sedation of Morbidly Obese Patients in the Endoscopy Suite
Status: COMPLETED
Conditions: Morbid Obesity|Noninvasive Ventilation|Deep Sedation
Interventions: DEVICE: High flow nasal cannula|DEVICE: Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Systemic Lidocaine on Postoperative Quality of Recovery After Robot-assisted Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: Systemic intravenous lidocaine infusion|DRUG: normal saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Less Discomfort and Less Pharmacology. Cataract Surgery at Physiologic Intraocular Pressure (IOP)
Status: RECRUITING
Conditions: Nuclear Cataract
Interventions: OTHER: High Intraocular Pressure (IOP)|OTHER: Low Intraocular Pressure (IOP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Upadacitinib|BIOLOGICAL: Dupilumab|DRUG: Placebo to dupilumab|DRUG: Placebo to upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Boost by Ablative Stereotactic Radiotherapy (SABR) vs Brachytherapy in Patients With Cervical Carcinoma
Status: RECRUITING
Conditions: Uterine Cervical Neoplasm
Interventions: RADIATION: SABR VS Intracavitary 3D Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of Cooling Anesthesia for Intravitreal Injection
Status: COMPLETED
Conditions: Anesthesia, Local|Intravitreal Injection|Macular Edema|Macular Degeneration|Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DEVICE: Recens Cooling Anesthesia Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Index/Saturated Fatty Acid Diet and Hepatic Fat
Status: COMPLETED
Conditions: Fatty Liver, Nonalcoholic|Diet, Healthy|Obesity
Interventions: BEHAVIORAL: High GI/SFA diet|BEHAVIORAL: Low GI/SFA diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Positive Cancer|Vulvar, Vaginal, Penile, Rectal Cancer|Anal Cancer|Oropharyngeal Cancer|Cervical Cancer
Interventions: BIOLOGICAL: PRGN-2009 (Phase I)|BIOLOGICAL: PRGN-2009 (Phase II)|BIOLOGICAL: M7824|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Bone scan|DIAGNOSTIC_TEST: CT scan|DIAGNOSTIC_TEST: Brain CT|DIAGNOSTIC_TEST: Brain MRI|PROCEDURE: Biopsy (Phase I)|PROCEDURE: Biopsy (Phase II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC114/rtv|DRUG: TMC114/rtv|DRUG: TMC114/rtv|DRUG: TMC114/rtv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Attempt Intubation Rate With Airtraq vs Macintosh Direct Laryngoscope
Status: UNKNOWN
Conditions: Intubation
Interventions: PROCEDURE: Tracheal Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants.
Status: UNKNOWN
Conditions: Congenital Heart Disease|Infant, Premature, Diseases
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Trial of Culturally-Appropriate Decision Aids for Smoking Cessation
Status: UNKNOWN
Conditions: Cigarette Smoking|Tobacco Use Disorder|Nicotine Dependence|Smoking Cessation
Interventions: DEVICE: Smoking Cessation Decision Aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest|Hypothermia
Interventions: DEVICE: Coolgard|DEVICE: ArcticSun|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: SMT-NK inj.+Pembrolizumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
Status: COMPLETED
Conditions: Blister|Wound of Skin|Epidermolysis Bullosa|Varicose Ulcer of Lower Limb
Interventions: DRUG: TCP-25 gel 0.86 mg/ml or placebo gel|DRUG: TCP-25 gel 2.9 mg/ml or placebo gel|DRUG: TCP-25 gel 8.6 mg/ml or placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Diet With the Recommended Amount of Polyunsaturated Fatty Acids, Increase Their Proportion in Maternal Milk?
Status: COMPLETED
Conditions: Breast Feeding
Interventions: DEVICE: Dietary advice|OTHER: Consumption of Bleu-Blanc-Coeur products|OTHER: No consumption of Bleu-Blanc-Coeur products|BIOLOGICAL: Blood sample|OTHER: Contact|OTHER: food questionnaire|OTHER: newborn faeces sample|OTHER: breast milk sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: CR845 0.25 mg|DRUG: CR845 0.50 mg|DRUG: CR845 1 mg|DRUG: CR845 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glucosamine as a Novel Adjunctive Therapy in Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Glucosamine sulfate|DRUG: triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SH T00186 Phase II/ III Optimal Drospirenone (DRSP) Dose Finding and Placebo-controlled Comparative Study
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: SH T04740B|DRUG: SH T00186DF|DRUG: SH T04740F|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Real-World Cohort Study of Adebrelimab Injection in the Treatment of Extensive-Stage Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Interventions: DRUG: First-line Adebrelimab regiment for advanced stage ES-SCLC|DRUG: Second-line and beyond Adebrelimab regiment for advanced stage ES-SCLC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-line Dasatinib Plus Conventional Chemotherapy in Adults With Newly Diagnosed Ph-Positive ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Dasatinib|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Daunorubicin|DRUG: Dexamethasone|DRUG: Cytarabine|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occlusal ART Restorations in Primary Molars Using 3 Different GIC
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Restoration with Fuji IX|PROCEDURE: Restoration with Vitro Molar|PROCEDURE: Restoration with Maxxion R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Do Preoperative Carbohydrate Drinks Prevent Preoperative Catabolism in Mothers Undergoing Elective Caesarean Section? A Randomised Controlled Study
Status: UNKNOWN
Conditions: Starvation|Caesarean Section
Interventions: DIETARY_SUPPLEMENT: Vitaflow Preload
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Registry Study of Extracorporeal Cardiopulmonary Resuscitation (eCPR) in China
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation Complication|Cardiopulmonary Arrest
Interventions: DEVICE: extracorporeal membrane oxygenation (ECMO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: C: BI 10773 / metformin tablet|DRUG: B: BI 10773 tablet and metformin tablet|DRUG: A: BI 10773 / metformin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Pharmacokinetics of Pegolsihematide for Treatment of Anemia Patient With Myelodysplastic Syndromes
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes|Anemia
Interventions: DRUG: Pegol-sihematide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathogenetic Basis of Aortopathy and Aortic Valve Disease
Status: RECRUITING
Conditions: Aortopathies|Thoracic Aortic Aneurysm|Aortic Valve Disease|Thoracic Aortic Disease|Thoracic Aortic Dissection|Thoracic Aortic Rupture|Ascending Aortic Disease|Descending Aortic Disease|Ascending Aortic Aneurysm|Descending Aortic Aneurysm|Marfan Syndrome|Loeys-Dietz Syndrome|Vascular Ehlers-Danlos Syndrome|Shprintzen-Goldberg Syndrome|Turner Syndrome|PHACE Syndrome|Autosomal Recessive Cutis Laxa|Congenital Contractural Arachnodactyly|Arterial Tortuosity Syndrome|Bicuspid Aortic Valve-Associated Aortopathy|Bicuspid Aortic Valve|Familial Thoracic Aortic Aneurysm and Aortic Dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DECLIC Patient Education Program : Assessment Through a Population Health Intervention Research Approach (LE DECLIC EPRI)
Status: RECRUITING
Conditions: Cancer Patients With Cancer Pain
Interventions: OTHER: Experimental group|OTHER: standrad group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perindopril Amlodipine for the Treatment of Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: XOMA 985|DRUG: Amlodipine Besylate|DRUG: Perindopril Erbumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rescue of Steroidogenic Capacity in Adrenocortical Failure Study (RADS)
Status: COMPLETED
Conditions: Autoimmune Adrenocortical Failure
Interventions: DRUG: Solu-medrone, Mabthera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Insulin Glulisine Compared With Insulin Aspart on Breakfast Post Prandial Glucose Levels in Prepubertal Children
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: insulin glulisine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Two Contraceptive Vaginal Rings Delivering a Daily Dose of 1500 or 2500 μg of CDB-2914
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: CDB-2914
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for the Prevention of Episodic Migraine (MPEM)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Metformin|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diet and Hypnotic Suggestions or Telemedicine in Obesity Management
Status: COMPLETED
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: Dietary counseling via face to face meeting|BEHAVIORAL: Telemedicine|BEHAVIORAL: Hypnotic Suggestions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QPI-1002 Phase 3 for Prevention of Major Adverse Kidney Events (MAKE) in Subjects at High Risk for AKI Following Cardiac Surgery
Status: TERMINATED
Conditions: Cardiac Surgery
Interventions: DRUG: teprasiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma
Status: RECRUITING
Conditions: Adamantinomatous Craniopharyngioma|Recurrent Adamantinomatous Craniopharyngioma
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: PRIME|OTHER: COMBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
Status: ENROLLING_BY_INVITATION
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: L-PRF and H-PRF|PROCEDURE: Impacted Tooth Removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxol Every 2 Week Versus Paclitaxol Every 1 Week in the Adjuvant Treatment of Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Paclitaxel|Epirubicin|Cyclophosphamide
Interventions: DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting FMO-Mediated TMAO Formation in Kidney Disease (TMAO) Study
Status: COMPLETED
Conditions: Kidney Diseases|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Commercially available Diindolylmethane|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sungurtekin Technique vs. Closed Lateral Internal Sphincterotomy Technique
Status: UNKNOWN
Conditions: Anal Fissure
Interventions: PROCEDURE: Sungurtekin Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testosterone in Bariatric Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Bariatric Surgery Candidate|Male Hypogonadism|Muscle Loss
Interventions: DRUG: Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone
Status: WITHDRAWN
Conditions: Caesarean Delivery
Interventions: DRUG: TAP Block|DRUG: Ropivacaine|DRUG: Acetaminophen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Basics of Bihemispheric Motorcortex Stimulation After Stroke
Status: COMPLETED
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: tDCS|BEHAVIORAL: Motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Poliovirus Type 2 Immunogenicity of One and Two Dose Schedule With IPV and fIPV When Administered at 9-13 Months of Age in Bangladesh
Status: UNKNOWN
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Laquinimod in Participants With Systemic Lupus Erythematosus (SLE) Active Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Laquinimod|DRUG: Mycophenolate Mofetil|DRUG: Prednisolone/Prednisone|DRUG: Placebo|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms|Lymphoma, Non-Hodgkin
Interventions: DRUG: PD-0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyslipidemias|Hypercholesterolemia|Familial Hypercholesterolemia|ASCVD|High Cholesterol
Interventions: COMBINATION_PRODUCT: Combination Therapy|DRUG: Monotherapy obicetrapib|DRUG: Monotherapy ezetimibe|OTHER: Combination Therapy placebo|OTHER: Obicetrapib Placebo|OTHER: Ezetimibe Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Zr-Panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Head-and-neck Squamous Cell Carcinoma
Interventions: DRUG: 89Zr-panitumumab IV|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophrenia
Status: COMPLETED
Conditions: Herpes Simplex|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Experimental: Valacyclovir treatment|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of ABT-089 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: ABT-089|DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loteprednol Etabonate Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Inflammation|Pain|Cataract
Interventions: DRUG: Loteprednol Etabonate Gel (BID)|DRUG: Vehicle Gel (BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure|Acute Heart Failure
Interventions: DRUG: Finerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Hippocampal Neuroplasticity for Surfacing of Inaccessible Traumatic Memories in Veterans With PTSD
Status: RECRUITING
Conditions: PTSD|Peritraumatic Amnesia
Interventions: OTHER: HBOT|OTHER: Hippocampal training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROPENSITY-ID: Sonographic and Clinical Assessment of Head Position Prior to Instrumental Delivery and Labour Outcomes
Status: UNKNOWN
Conditions: Instrumental Delivery|NEC, Affecting Fetus or Newborn|Second Stage Cesarean Delivery|Occiput Position
Interventions: DIAGNOSTIC_TEST: Intrapartum sonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iron Status and Myelination in Premature Infants
Status: COMPLETED
Conditions: Neurodevelopmental Outcome
Interventions: DIETARY_SUPPLEMENT: iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases
Status: COMPLETED
Conditions: Mumps|Rubella|Measles|Varicella
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Chickenpox (live vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Total Facet Arthroplasty System®(TFAS®) Clinical Trial
Status: UNKNOWN
Conditions: Spinal Stenosis|Low Back Pain|Spondylolisthesis|Lumbar Spinal Stenosis|Leg Pain|Spinal Diseases
Interventions: DEVICE: Total Facet Arthroplasty System® (TFAS®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Status: RECRUITING
Conditions: Cancer Harboring BRAF Alterations
Interventions: DRUG: Plixorafenib|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Bicarbonate To Verify The Correct Position of IV Catheters in Oncological Patients Oncological Patients Receiving Chemotherapy
Status: UNKNOWN
Conditions: Detection of the Correct Position of Intravenous Line
Interventions: DRUG: sodium bicarbonate 4.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC