pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Erythropoietin in the Treatment of Anemia After Autologous Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Anemia|Lymphoma|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: erythropoietin|DRUG: iron supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-radiation Dose CT Angiography With Invasive Coronary Angiography in Stable Coronary Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Cardiac Computer Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Ghost Ileostomy in Laparoscopic Rectal Resection
Status: COMPLETED
Conditions: Colo-rectal Anastomosis Dehiscence
Interventions: PROCEDURE: Ghost Ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Xueshuanxinmaining Tablet for the Treatment of Stable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Heart Disease|Stable Angina
Interventions: DRUG: Xueshuanxinmaining tablet|DRUG: Xueshuanxinmaining placebo|DRUG: Nitroglycerin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy and Deontology in the Temporomandibular Joint Dysfunction in Patients With Fibromyalgia Syndrome.
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Physiotherapy Protocol|OTHER: Deontology Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|PTSD|Cognitive Dysfunction
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Cognitive training placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Fast-track Surgery Program for Total Hip and Knee Replacement and the Evaluation of the Risks and Benefits for the Patient
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthopedic Procedure
Interventions: PROCEDURE: Fast-track Total Hip and knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prehabilitation for Ovarian Cancer Patients
Status: RECRUITING
Conditions: Prehabilitation|Exercise|Frailty|Ovarian Cancer|Surgical Complication|Treatment Outcomes|Enhanced Recovery After Surgery
Interventions: BEHAVIORAL: Prehabilitation Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes
Status: TERMINATED
Conditions: Pain
Interventions: OTHER: Pharmacogenomic Testing|DRUG: Ibuprofen|DRUG: hydroxycontin/acetominophen|DRUG: acetominophen|DRUG: Oxycontin/acetominophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Lower Limb Functionality, Knee Joint Position Sense, Balance and Falls in Haemiplegic Patients
Status: NOT_YET_RECRUITING
Conditions: Haemiplegic Patients|Balance|Knee Joint Position Sensation|Lower Limb Functionality
Interventions: OTHER: Tecno Body Prokin Isokinetic Balance System|OTHER: Restorative Therapies RT300 leg/arm/cor:|OTHER: CSMI (CYBEX) Humac Norm Isokinetic Test and Exercise System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mixed Urinary Incontinence Surgical Trial
Status: COMPLETED
Conditions: Med: Urinary Incontinence (Stress, Urge, Mixed)
Interventions: PROCEDURE: Burch Colposuspension|PROCEDURE: trans obturator tape|PROCEDURE: tension free vaginal tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endolaparoscopic Versus Immediate Surgery for Obstructing Colorectal Cancers
Status: UNKNOWN
Conditions: Colorectal Cancer|Bowel Obstruction
Interventions: PROCEDURE: Endoscopic stenting followed by elective laparoscopic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Neladenoson bialanate (BAY1067197)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bladder Morphology Using 2 Different Catheter Designs
Status: UNKNOWN
Conditions: Urologic Injuries|Urologic Diseases|Bladder Infection|Urinary Tract Infections|Mucosal Inflammation|Mucosal Infection|Bladder Injury|Catheter-Related Infections|Catheter Complications|Catheter; Infection (Indwelling Catheter)|Pelvic Floor Disorders|Urinary Incontinence
Interventions: DEVICE: Cystosure Urinary Access System|DEVICE: Foley Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Comparing the Efficacy and Safety of GZR4 Injection Versus Insulin Degludec in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GZR4 Injection|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress & Self-Control Costs
Status: RECRUITING
Conditions: Self-Control
Interventions: BEHAVIORAL: Cold-Pressor Task (CPT)|BEHAVIORAL: Trier Social Stress Test (TSST)|BEHAVIORAL: Modified Non-Stress CPT|BEHAVIORAL: Modified Non-Stress TSST|DEVICE: Functional Magnetic Resonance Imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optical Biopsy and Fallopian Tube
Status: COMPLETED
Conditions: Bilateral Laparoscopic Salpingectomy
Interventions: PROCEDURE: bilateral laparoscopic salpingectomy|DEVICE: endomicroscopy Cellvizio® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: metformin|DRUG: BI 187004|DRUG: BI 187004|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Safety and Efficacy Study of Mebendazole on GI Cancer or Cancer of Unknown Origin.
Status: TERMINATED
Conditions: Cancer of the Gastrointestinal Tract|Cancer of Unknown Origin
Interventions: DRUG: ReposMBZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib in Combination With Pembrolizumab and Carboplatin as First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Head and Neck Squamous Cell Carcinoma|Metastatic Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Olaparib|DRUG: Pembrolizumab|DRUG: Carboplatin|PROCEDURE: Peripheral blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Effect on Platelet Aggregation Following Infant Cardiopulmonary Bypass
Status: WITHDRAWN
Conditions: Heart Defect, Congenital
Interventions: DRUG: Tranexamic Acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep rTMS (Repetitive Transcranial Magnetic Stimulation)for Treatment of Autism Symptoms in Children.
Status: TERMINATED
Conditions: Autism
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complete Mesogastric Excision With D2 Lympadenectomy for Gastric Cancer:
Status: COMPLETED
Conditions: Gastric Cancer|Gastric Neoplasm|Gastric Cancer Stage
Interventions: PROCEDURE: Total mesogastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidism
Status: TERMINATED
Conditions: Hypoparathyroidism
Interventions: DRUG: PCO371|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of an Inactivated Vaccine Against Hand, Foot and Mouth Disease Caused by Enterovirus 71
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: INV21 Low Dose|BIOLOGICAL: INV21 High Dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The CASCADE HF Soft Launch and Calibration Phase I and II
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Non-Invasive Continuous Remote Patient Monitoring|OTHER: Affective Analysis of Participant Response to Continuous Remote Patient Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endoscopic Access Loop With Bilio-enteric Anastomosis: A Prospective Randomized Comparison Between Gastric and Subcutaneous Accesses
Status: UNKNOWN
Conditions: Jaundice, Obstructive
Interventions: PROCEDURE: hepaticojejunostomy|PROCEDURE: modified hepaticojejunostomy with subcutaneous access loop|PROCEDURE: modified hepaticojejunostomy with gastric access loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serial ECG Versus Holter to Detect Atrial Fibrillation in Elderly Ischemic Stroke Patients
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Electrocardiogram|DEVICE: Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot Study
Status: COMPLETED
Conditions: Port-wine Stains
Interventions: DRUG: Bosentan|DEVICE: Pulsed dye laser (PDL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir Alafenamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Status: RECRUITING
Conditions: Severe Combined Immunodeficiency|Malignancy, Hematologic|Neuroblastoma|Neoplasm|Mucopolysaccharidosis I
Interventions: PROCEDURE: Venipuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repetitive Transcranial Magnetic Stimulation Associated With Physical Therapy to Reduce Upper Limb Spasticity in Post Stroke Patients
Status: UNKNOWN
Conditions: Chronic Stroke
Interventions: DEVICE: TMS|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EP0057 in Combination With Olaparib in Relapsed Advanced Gastric Cancer and Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Gastric Cancer|Small-cell Lung Cancer
Interventions: DRUG: EP0057|DRUG: Olaparib tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Colding of Endotracheal Tubes on Sore Throat
Status: RECRUITING
Conditions: Postoperative Sore Throat
Interventions: OTHER: cold endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Assessment of the Safety of Varenicline in Methamphetamine-dependent Volunteers
Status: COMPLETED
Conditions: Methamphetamine Addiction|Crystal Meth Addiction|Amphetamine Addiction
Interventions: DRUG: Varenicline, then placebo|DRUG: Placebo, then varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of RhuMab-E25 in Reducing Exhaled Nitric Oxide (NO) in Allergic Asthma
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: RhuMab-E25
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Double-blind Study on the Treatment of Osteoarthritis of the Bilateral Knee: Autologous Bone Marrow Concentrate vs. Hyaluronic Acid
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: injection of autologous bone marrow concentrate|BIOLOGICAL: injection of hyaluronic acid.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Baduanjin on Physical Fitness and Bone Density in Maintenance Hemodialysis Patients
Status: RECRUITING
Conditions: Rehabilitation|Physical Fitness|Bone Density|Hemodialysis Complication
Interventions: BEHAVIORAL: Baduanjin exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Subjects With Progressive Supranuclear Palsy (PSP)
Status: TERMINATED
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: Placebo|DRUG: ABBV-8E12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics|Drug-Drug Interaction
Interventions: DRUG: MDV3100|DRUG: Gemfibrozil|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Assess the Safety and Efficacy of the 4 Channel NMES, Pilot Study
Status: TERMINATED
Conditions: Dysphagia
Interventions: DEVICE: 4 channel Electrical Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Simtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASH
Status: TERMINATED
Conditions: Liver Fibrosis Due to NASH
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: SIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Utapine vs. Seroquel in Patients With Bipolar Mania
Status: UNKNOWN
Conditions: Bipolar, Mania|Utapine|Seroquel
Interventions: DRUG: Utapine|DRUG: Seroquel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TEA vs. PVB vs. PCA in Liver Resection Surgery
Status: TERMINATED
Conditions: Pain Management Strategies in Liver Resection Surgery
Interventions: DEVICE: thoracic epidural|DEVICE: continuous paravertebral catheter|DRUG: Patient-Controlled Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Single Dose Study of Oral Lasmiditan in Participants With Normal and Impaired Hepatic Function
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: lasmiditan 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of a Test Naproxen Sodium 220mg Tablet in Postoperative Dental Pain
Status: COMPLETED
Conditions: Post-operative Dental Pain
Interventions: DRUG: Test naproxen sodium tablet|DRUG: Commercial naproxen sodium tablet|DRUG: Commercial naproxen sodium liquid gels capsule|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome
Status: TERMINATED
Conditions: Relapsed Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Richter Syndrome|MYC Amplification|MYC Overexpression|MYC Translocation
Interventions: DRUG: VIP152|DRUG: BTKi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy; Seizure|Neuromuscular Diseases|Brain Malformation|Intellectual Disability|Autism Spectrum Disorder|Hypotonia|Inborn Errors of Metabolism|Movement Disorders|Genetic Disease|Development Delay|Chromosome Abnormality|Hearing Loss|Dysmorphic Features|Skeletal Dysplasia|Congenital Abnormality|Microcephaly|Macrocephaly
Interventions: BEHAVIORAL: Pre-visit prep|DIAGNOSTIC_TEST: usual care + exome seq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Normal and Pathological Values of Postvoiding Residual Volume in Early Postpartum Period and Their Predisposing Factors
Status: TERMINATED
Conditions: Urinary Retention
Interventions: DIAGNOSTIC_TEST: Ultrasound measurement of residual volume in the urinary bladder|DIAGNOSTIC_TEST: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Non Alcoholic Fatty Liver|Non Alcoholic Steatohepatitis|NAFLD|NASH
Interventions: DRUG: Hyperpolarized (HP) 13C|DRUG: Hyperpolarized 13C-Urea|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Saline Flush
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multimodal Enhanced Recovery Program in Anorectal Surgery
Status: TERMINATED
Conditions: Colorectal Disorders|Anorectal Disorder|Patient Satisfaction|Pain, Postoperative|Opioid Use|Opioid Abuse|Opioid Dependence
Interventions: PROCEDURE: ReCOVER Enhanced Recovery Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse Events
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: RZL-012|DRUG: RZL-012+Lidacaine injection prior treatment|DRUG: RZL-012+Medrol|DRUG: RZL-012+Celecoxib+Zyrtec|DRUG: RZL-012+facial and neck wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Trial for Circadian Rest-activity Rhythm Disorders in Cancer (RALI)
Status: RECRUITING
Conditions: Circadian Rhythm Disorders|Cancer
Interventions: BEHAVIORAL: Cognitive behavioural therapy for Insomnia (CBT-I)|DEVICE: Bright Light Therapy|BEHAVIORAL: Individualised activity plan|OTHER: Clincial review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abrupt Versus Tapered Interruption of Chronic Clopidogrel Therapy After DES Implantation
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Abrupt Clopidogrel Interruption|DRUG: Clopidogrel Tapering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction
Status: COMPLETED
Conditions: Sepsis|Acute Kidney Injury Due to Sepsis|Septic Shock|Acute Respiratory Distress Syndrome
Interventions: OTHER: Supportive therapy at the ICU|OTHER: Sepsis therapy|OTHER: Sepsis-related organ dysfunction therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Oral Cinnamon Extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Basmisanil Treatment in Children Aged 2-14 Years With Dup15q Syndrome
Status: TERMINATED
Conditions: Dup15q Syndrome
Interventions: DRUG: Basmisanil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness
Status: COMPLETED
Conditions: Muscle Damage
Interventions: PROCEDURE: cold water immersion|DIETARY_SUPPLEMENT: beta-hydroxy-beta-methylbutyrate free acid (HMB-FA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization
Status: COMPLETED
Conditions: IVF
Interventions: DEVICE: OPT-IVF dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-Term Effect of Combined Citrulline and Nitrate-Rich Beetroot Extract Supplementation
Status: COMPLETED
Conditions: Citrulline|Nitrate|Athletes
Interventions: DIETARY_SUPPLEMENT: Citrulline|DIETARY_SUPPLEMENT: Nitrate|DIETARY_SUPPLEMENT: Nitrate plus Citrulline|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetic Foot
Interventions: DEVICE: diabetic foot orthotic|OTHER: Standard innersole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinician JUdgment Versus Risk Score to Predict Stroke outComes: The JURASSIC Clinical Trial
Status: COMPLETED
Conditions: Stroke|Ischemic Stroke|Cerebrovascular Disease
Interventions: OTHER: Clinical scenarios
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Control Cohort CTRL COH
Status: RECRUITING
Conditions: Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis
Interventions: BIOLOGICAL: Collection of biological sample (blood and/or CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Endoscopic Variceal Ligation (EVL) With Propranolol in Non Cirrhotic Portal Hypertension (NCPH)
Status: COMPLETED
Conditions: Non Cirrhotic Portal Hypertension
Interventions: DRUG: Propranolol|DEVICE: multi band ligator for esophageal varices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on Adjuvant Chemotherapy After Total Two-field Lymph Node Dissection of Thoracic Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Thoracic Esophageal Squamous Cell Carcinoma
Interventions: DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation
Status: COMPLETED
Conditions: Hypercapnia|Ventilatory Depression
Interventions: DRUG: Oxycodone and Midazolam|DRUG: Oxycodone, Paroxetine, and Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dialectical Behavioral Therapy in Juvenile Justice
Status: WITHDRAWN
Conditions: Non-Suicidal Self Injury|Suicide|Self-harm|Emotion Regulation
Interventions: BEHAVIORAL: Dialetical Behavioral Therapy for Adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Performance of the Modular AAA Stent-Graft System
Status: WITHDRAWN
Conditions: Cardiovascular Diseases|Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Endoprothesis Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Tissue Massage on Respiratory Parameters in Healthy People.
Status: COMPLETED
Conditions: Spirometry|Massage
Interventions: PROCEDURE: Deep tissue massage|PROCEDURE: Classic massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Omega-3 Fatty Acids|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Dynamic Stabilization (PDS) System Versus Fusion for Treating Degenerative Disc Disease
Status: TERMINATED
Conditions: Lumbar Degenerative Disc Disease
Interventions: DEVICE: PDS System|DEVICE: Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation With Nelfinavir for Oligometastases
Status: COMPLETED
Conditions: Oligometastases
Interventions: DRUG: Nelfinavir|RADIATION: Stereotactic Body Radiation (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol and Atherosclerosis Pilot Study
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: OTHER: ethanol|OTHER: Ethanol-free beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: SVC Occlusion in Subjects With Acute Decompensated Heart Failure
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure|Acute Heart Failure|Congestive Heart Failure|Heart Diseases
Interventions: DEVICE: preCARDIA system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Cognitive Rehabilitation Therapy for COVID-19
Status: ENROLLING_BY_INVITATION
Conditions: Post-Acute COVID-19 Syndrome
Interventions: BEHAVIORAL: Compensatory Cognitive Training for COVID-19|BEHAVIORAL: Holistic Cognitive Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of N-Acetylcysteine (N-AC)in People Receiving CAR T-cell Therapy for Lymphoma
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study on Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: neurological examination, Kurtzke EDSS, Barthel scale, ecocolor-Doppler|PROCEDURE: neurological evaluation, ecocolor-Doppler|PROCEDURE: medical history, vital signs, ecocolor-Doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Complete Molecular Response for Chronic Myeloid Leukemia in Chronic Phase Patients, Treated With Dasatinib
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute High Fat Bulletproof Coffee vs Black Coffee on Metabolism, Inflammation and Cognitive Function in Healthy Adults
Status: UNKNOWN
Conditions: Leukocytosis|Triglycerides|Cognitive Function|Inflammatory Response
Interventions: DIETARY_SUPPLEMENT: High-fat coffee|DIETARY_SUPPLEMENT: Black coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RADIOFREQUENCY TREATMENT OF CHRONIC PELVIC PAIN MANAGEMENT IN INTERSTITIAL CYSTITIS
Status: COMPLETED
Conditions: Interstitial Cystitis, Chronic
Interventions: PROCEDURE: superior hypogastric plexus pulsed radiofrequency and transcutaneous tibial nerve stimulation|PROCEDURE: superior hypogastric plexus pulsed radiofrequency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Trientine With Vemurafenib for the Treatment BRAF Mutated Metastatic Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: DRUG: Vemurafenib and Trientine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics in Patients Undergoing Surgery for Periampullary Neoplasms
Status: COMPLETED
Conditions: Periampullary Carcinoma Nos
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics of Testosterone Gel Using an Applicator
Status: COMPLETED
Conditions: Hypogonadal Males
Interventions: DRUG: Testosterone Gel (FE 999303)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Types of Distal Arteriovenous Fistulas: SBAVF, RCAVF, and RCAVF With Venous Branch Patch.
Status: RECRUITING
Conditions: Dialysis; Complications|Vascular Access Complication
Interventions: PROCEDURE: AVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolism of Bioactive Dietary Polyphenol Preparation (BDPP)
Status: RECRUITING
Conditions: Healthy Control
Interventions: DIETARY_SUPPLEMENT: Trans-resveratrol|DIETARY_SUPPLEMENT: Concord grape juice|DIETARY_SUPPLEMENT: Grape seed polyphenol extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaginal Dinoprostone Versus Vaginal Misoprostol Prior to Diagnostic Office Hysteroscopy in Postmenopausal Patients
Status: COMPLETED
Conditions: Office Hysteroscopy
Interventions: DRUG: Dinoprostone|DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes
Status: RECRUITING
Conditions: Plasmodium Vivax Infection
Interventions: BIOLOGICAL: An inoculum of malaria parasitised red blood cells with whole dose blood-stage inoculum|BIOLOGICAL: An inoculum of malaria parasitised red blood cells with 1:5 dilution blood-stage inoculum|BIOLOGICAL: An inoculum of malaria parasitised red blood cells with 1:10 dilution blood-stage inoculum|BIOLOGICAL: An inoculum of malaria parasitised red blood cells with 1:20 dilution blood-stage inoculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Edentulous; Alveolar Process, Atrophy
Interventions: OTHER: Melatonin and hyaluronic acid and sinus membrane elevation|PROCEDURE: sinus membrane elevation without any materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma.
Status: UNKNOWN
Conditions: Papillary Thyroid Microcarcinoma
Interventions: PROCEDURE: Radiofrequency Ablation|PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Between Indomethacin and Pancreatic Stenting in the Prevention of Post ERCP Pancreatitis
Status: RECRUITING
Conditions: Post ERCP Pancreatitis
Interventions: DEVICE: pancreatic stenting|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Irinotecan|DRUG: Capecitabine|DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of SYN006 HFA MDI in Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Procaterol, 180/10mcg X1|DRUG: Budesonide/procaterol 180/10 mcg X 2|DRUG: Albuterol HFA MDI 100mcg X2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies
Status: COMPLETED
Conditions: EBV-induced Lymphomas|EBV-associated Malignancies|Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma
Interventions: BIOLOGICAL: EBV-specific T cells (EBV-CTLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease
Status: COMPLETED
Conditions: Brain Imaging|Mild Cognitive Impairment|Alzheimer Disease|Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR
Status: COMPLETED
Conditions: Prostatic Neoplasms|Breast Neoplasms|Colorectal Neoplasms|Melanoma|Leukemia
Interventions: BEHAVIORAL: Interactive Voice Response (IVR) Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Conventional Photodynamic Therapy vs. Painless Photodynamic Therapy for Actinic Keratosis
Status: UNKNOWN
Conditions: Actinic Keratosis
Interventions: PROCEDURE: Aminolevulinic acid photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 611(Recombinant Humanized Anti-interleukin-4 Receptor Alpha IgG4 Monoclonal Antibody) in Chinese Adults With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis, Atopic
Interventions: DRUG: 611|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Disorder|Anterior Knee Pain Syndrome
Interventions: OTHER: Electromyographic-biofeedback guided (EMG-BF) isometric quadriceps strengthening with patellar taping five days a week for six weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2
Status: WITHDRAWN
Conditions: Heart Failure NYHA Class I|Heart Failure NYHA Class II|Heart Failure NYHA Class III
Interventions: DRUG: Valsartan 80 mg bid|DRUG: Enalapril 10 mg bid|DRUG: Sacubitril-Valsartan 200 mg bid|DRUG: Icatibant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diaphragm Release Manual Technique Efficacy in COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Manual Diaphragm Release Technique|OTHER: Manual Diaphragm release technique (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study to Assess the Safety and Tolerability of APO866 for the Treatment of Refractory B-CLL
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia
Interventions: DRUG: APO866
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Versus Ketorolac for Perioperative Pain Control After Open Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain|Hysterectomy
Interventions: DRUG: Ketorolac Injectable Solution|DRUG: Ibuprofen 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 'Single Hand Used inTubaTing Laryngoscope Evaluation' Study
Status: UNKNOWN
Conditions: Respiratory Failure|Cardiac Arrest|Difficult Intubation|Anesthesia Intubation Complication
Interventions: DEVICE: ShuttleScope|DEVICE: MacIntosh Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: One-year, Open Extension to Evaluate the Treatment of Patients With Castration-Resistant Prostate Cancer With YONSA™
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: abiraterone acetate with Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Autologous Human Umbilical Cord Blood Treatment for Perinatal Arterial Ischemic Stroke
Status: SUSPENDED
Conditions: Perinatal Arterial Ischemic Stroke
Interventions: BIOLOGICAL: Autologous Cord Blood Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Kiwifruit Effect on Periodontal Inflammation Kiwifruit Effect on Periodontal Inflammation
Status: COMPLETED
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Kiwifruit addition to the diet|PROCEDURE: Non Surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cervical Internal os Plasty in Management of Placenta Previa and Focal Accreta
Status: UNKNOWN
Conditions: Cervical IO Plasty in Management of Placenta Previa
Interventions: COMBINATION_PRODUCT: cervical internal os plasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gestational Obesity and Interventions With Probiotics or Fish Oil Trial
Status: UNKNOWN
Conditions: Obesity|Pregnancy|Inflammation
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of CAM2038, Long-acting Subcutaneous Buprenorphine Injections for Treatment of Patients With Opioid Dependence
Status: COMPLETED
Conditions: Opioid Use Disorders
Interventions: DRUG: CAM2038 SC injection|DRUG: SL BPN/NX tabs|DRUG: placebo SC injections|DRUG: SL placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) of the Globus Pallidus (GP) in Huntington's Disease (HD)
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DEVICE: ACTIVA® PC neurostimulator (Model 37601)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Local Food Solutions for the Prevention of Acute Malnutrition in Tigray, Northern Ethiopia (ELOFSAM)
Status: RECRUITING
Conditions: Acute Malnutrition in Childhood
Interventions: DIETARY_SUPPLEMENT: Bahgina|DIETARY_SUPPLEMENT: SQLNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intradiscal Gelified Ethanol and Pulsed Radiofrequency Versus Gelified Ethanol Injection for Discogenic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Gelified ethanol combined to pulsed radiofrequency|DRUG: Gelified ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: ALS - Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Atalante exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: RO5323441 + bevacizumab [Avastin]|DRUG: bevacizumab [Avastin]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent-mediated Family Diabetes Intervention: American Samoa
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes Intervention|BEHAVIORAL: Leadership & Life Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT