pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: In Vivo Assessment of the Elastic Properties of Women's Pelvic Floor During Pregnancy
Status: UNKNOWN
Conditions: Pregnancy
Interventions: OTHER: Perineal ultrasound assessment|OTHER: Peripheral muscles assessment|OTHER: Clinical pelvic floor assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Apnoeic Oxygenation During Pediatric Tracheal Intubation: a Randomized Controlled, Single-blinded Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Airway Complication of Anesthesia|Anesthesia; Adverse Effect
Interventions: OTHER: apnoeic Oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcomes of Patients With Stage IV Chronic Limb-threatening Ischemia and Colorectal Cancer
Status: COMPLETED
Conditions: Chronic Limb-Threatening Ischemia|Colorectal Carcinoma|Colorectal Carcinoma Metastatic in the Liver
Interventions: PROCEDURE: For chronic limb-threatening ischemia (CLTI) patients revascularisation surgery; for colorectal liver metastasis (CRLM) patients metastatic liver surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial With Autologous Dendritic Cell Vaccination in Patients With Stage II-III HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Stage II Breast Cancer|Stage III Breast Cancer
Interventions: BIOLOGICAL: Autologous dendritic cell vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury
Status: RECRUITING
Conditions: Brain Injury Traumatic Mild|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction class|BEHAVIORAL: Brain Health Education class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neutrophils and Circulating Platelets in Correlation With the Activity of T Lymphocytes in Patients With NAFLD (Nonalcoholic Fatty Liver Disease)
Status: UNKNOWN
Conditions: NAFLD- Non Alcoholic Fatty Liver Disease
Interventions: DIAGNOSTIC_TEST: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Goldstein SonoBiopsy™ Catheter for Diagnosing Endometrial Pathology
Status: TERMINATED
Conditions: Menorrhagia|Endometrial Neoplasms|Polycystic Ovary Syndrome|Uterine Neoplasms
Interventions: DEVICE: SonoBiopsy Catheter|DEVICE: Endometrial biopsy catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: AML, Adult|Minimal Residual Disease
Interventions: DRUG: CD33/CLL1 dual CAR-NK cell|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: CD33 CAR-NK cell|DRUG: super NK cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Follow-up of Direct/Indirect Bridge, Orthodontic and Periodontal Splint by Using Fibre-reinforced Composite
Status: UNKNOWN
Conditions: Tooth Loss|Tooth Mobility
Interventions: OTHER: Fibreglass reinforced composite restoration-everStick|DEVICE: everStick
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Effectiveness of mRNA-1273 COVID-19 Vaccine in Healthy Children Between 6 Months of Age and Less Than 12 Years of Age
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273|BIOLOGICAL: Placebo|BIOLOGICAL: mRNA-1273.214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Motor Imagery on Motor Learning and Motor Retention in Octogenarian.
Status: TERMINATED
Conditions: Aging
Interventions: OTHER: motor imagery as training manual task|OTHER: motor imagery as training motor task|OTHER: emotionally neutral film as training of manual task|OTHER: emotionally neutral film as training of motor task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Monitoring Patients Who Are Obese Surgery for Gastric By-pass Protein Supplementation and Physical Training (PROMISE)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Protein supplementation and strength training|DIETARY_SUPPLEMENT: Protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RF Power, LSI and Oesophageal Temperature Alerts During AF Ablation (PiLOT-AF Study)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Combination 1 of radiofrequency (RF) power and Lesion Size Index (LSI) on left atrial (LA) posterior wall|PROCEDURE: Combination 2 of radiofrequency (RF) power and Lesion Size Index (LSI) on left atrial (LA) posterior wall|PROCEDURE: Combination 3 of radiofrequency (RF) power and Lesion Size Index (LSI) on left atrial (LA) posterior wall|PROCEDURE: Combination 4 of radiofrequency (RF) power and Lesion Size Index (LSI) on left atrial (LA) posterior wall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibre-optic Guided Tracheal Intubation Through SADs
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Laryngeal Masks|Airway Management
Interventions: DEVICE: I-gel|DEVICE: LMA Protector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Long-term Ivacaftor Treatment in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age at Treatment Initiation and Have an Approved Ivacaftor-Responsive Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Small-group, Virtual Program for Improving Symptoms and Distress Related to Hormonal Therapy for Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Adherence, Medication
Interventions: OTHER: STRIDE|OTHER: Medication Monitoring Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Managing Colorectal Cancer Prevention Procedure Wait Lists During the COVID-19 Pandemic
Status: WITHDRAWN
Conditions: Adenomatous Polyps
Interventions: DIAGNOSTIC_TEST: colonoscopy|DIAGNOSTIC_TEST: FIT test|DIAGNOSTIC_TEST: CT colonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess Efficacy and Safety of NS-018 Compared to BAT in Patients With Myelofibrosis
Status: TERMINATED
Conditions: Primary Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis|Post-polycythemia Vera Myelofibrosis
Interventions: DRUG: NS-018|DRUG: Best Available Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without MEDI-522 in Treating Patients With Unresectable or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Recurrent Renal Cell Cancer|Renal Cell Carcinoma|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: etaracizumab|BIOLOGICAL: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Frontotemporal Lobar Degeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Trizivir|DRUG: Lamivudine/Zidovudine|DRUG: Lopinavir/Ritonavir|DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Team Approach to Polypharmacy Evaluation and Reduction in a Long-Term Care Setting
Status: TERMINATED
Conditions: Long-term Care|Polypharmacy|Frailty
Interventions: OTHER: Medication Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epcoritamab, Zanubrutinib, and Rituximab (EZR) for R/R FL Relapsed or Refractory Follicular Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Follicular Lymphoma|Lymphoma|Non-Hodgkin Lymphoma|Relapsed Lymphoma|Refractory Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab|DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness
Status: COMPLETED
Conditions: Major Depression|Schizophrenia|Bipolar Disorder|Lung Cancer|Breast Cancer|Head and Neck Cancer|GI Cancer|Cancer
Interventions: OTHER: Proactive Psychiatry Consultation (PPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gastric Barrier Dysfunction of Functional Dyspepsia and Therapeutic Response to Puyuanhewei Detected by Endomicroscopy
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DEVICE: pCLE examination|DRUG: Puyuanhewei
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Biological Activity and Safety of Low Dose IL2 in Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: IL2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Serplulimab Plus Chemotherapy in Neoadjuvant and Adjuvant Treatment of Resectable NSCLC (ECTOP-1013)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Stage II-IIIA|Immunotherapy|Neoadjuvant Therapy
Interventions: DRUG: Serplulimab and Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Fluorouracil (5-FU)|DRUG: Capecitabine|BIOLOGICAL: Durvalumab|DRUG: Oxaliplatin|BIOLOGICAL: Trastuzumab|DRUG: Trastuzumab deruxtecan|DRUG: Cisplatin|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Volrustomig|BIOLOGICAL: Rilvegostomig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Multiple-dose of Fluvoxamine on the Plasma Concentration of Quetiapine (FK949E) in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Quetiapine
Interventions: DRUG: FK949E|DRUG: fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
Status: RECRUITING
Conditions: Ganglioneuroblastoma, Nodular|Neuroblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|BIOLOGICAL: Dinutuximab|DRUG: Doxorubicin|DRUG: Etoposide|PROCEDURE: FDG-Positron Emission Tomography and Computed Tomography Scan|PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Irinotecan|DRUG: Isotretinoin|PROCEDURE: Leukapheresis|PROCEDURE: Magnetic Resonance Imaging|DRUG: Melphalan|RADIATION: Radiation Therapy|PROCEDURE: Radionuclide Imaging|OTHER: Survey Administration|DRUG: Temozolomide|DRUG: Thiotepa|DRUG: Topotecan|PROCEDURE: Tumor Resection|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tramadol Versus Lidocaine Infiltration for Tonsillectomy
Status: COMPLETED
Conditions: Peri-tonsillar Analgesic Infiltration|Tonsillectomy|Postoperative Pain|Inflammatory Response
Interventions: DRUG: peritonsillar infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Classic Versus Reversal Stapedotomy
Status: COMPLETED
Conditions: Otosclerosis of Middle Ear
Interventions: PROCEDURE: Endoscopic classic stapedotomy|PROCEDURE: Endoscopic reversal stapedotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapting, Expanding and Evaluating ARCHES in Kenya
Status: RECRUITING
Conditions: Reproductive Coercion|Intimate Partner Violence
Interventions: BEHAVIORAL: ARCHES (Addressing Reproductive Coercion in Health Settings)|BEHAVIORAL: BCS+ (Balanced Counseling Strategy Plus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of S-nitrosohemoglobin in Regulating Systemic Blood Flow During Hypoxia and Normoxia
Status: TERMINATED
Conditions: Focus is Determination of the Role of SNO-Hb in Forearm Blood Flow Regulation
Interventions: DRUG: Oral N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Randomized Study Comparing One or Two High Dose Chemotherapy Regimen Followed by Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Zavedos|DRUG: Cerubidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue
Status: RECRUITING
Conditions: Fatigue
Interventions: DRUG: Ketamine|DRUG: Midazolam (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BARIcitinib Cognitive Emotional and Neural signaTuRE
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Baricitinib Oral Tablet [Olumiant]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Campath-1H Plus Rituximab for CD52- and CD20- Positive Refractory or Relapsed Chronic Lymphoid Disorders
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Campath-1H|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Onvansertib|DRUG: Nanoliposomal irinotecan|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Continuous Dexmedetomidine Infusion on Systemic Microvascular Function in Laparoscopic Cholecystecthomy
Status: RECRUITING
Conditions: Laparoscopic Surgery
Interventions: DRUG: dexmedetomidine intravenous infusion|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine or Gemcitabine and Cisplatin in the Treatment of Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LI-TASTE Study: Light for Taste
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DEVICE: LX2.3 Laser and LED Photobiomodulation System|DEVICE: LX2.3 Laser and LED Photobiomodulation System Sham-PBMT Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
Status: RECRUITING
Conditions: Dry Age-related Macular Degeneration|Geographic Atrophy|Retinal Disease|Macular Degeneration|Macular Atrophy|Retinal Degeneration|Eye Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Efficacy and Safety of Halobetasol Propionate Lotion 0.05% in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Plaque Psoriasis
Interventions: DRUG: Halobetasol Propionate Lotion 0.05%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes
Status: UNKNOWN
Conditions: Gestational Diabetes|Pregnancy Complications|Weight Gain
Interventions: BEHAVIORAL: Habits-GDM mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Correlation Analysis of POD and pNCD in Elderly Patients With Gastrointestinal Neoplasms Based on Rs-fMRI
Status: NOT_YET_RECRUITING
Conditions: Postoperative Delirium|Postoperative Neurocognitive Disorder|Gastrointestinal Surgery
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis
Status: RECRUITING
Conditions: Diabetic Ketoacidosis
Interventions: DRUG: 200mg IV thiamine in 50mL 0.9% saline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diphtheria, Tetanus, Poliomyelitis -Pertussis-Hib Immunisation in Preterm-born Neonates
Status: UNKNOWN
Conditions: Hib Immunisation in Very Preterm-born Infants|Pertussis Immunisation in Very Preterm-born Infants
Interventions: BIOLOGICAL: Three vaccine injections DTP-pertussis-Hib|BIOLOGICAL: Two vaccine injections DTP-pertussis-Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Pioglitazone|DRUG: Placebo|BEHAVIORAL: Endurance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reformulated F75 Milk to Treat Severe Acute Malnutrition
Status: COMPLETED
Conditions: Malnutrition|Diarrhoea|Metabolic Disturbance
Interventions: DIETARY_SUPPLEMENT: Standard F75 Milk|DIETARY_SUPPLEMENT: Modified F75 Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic and Insulinemic Responses of Low-Carbohydrate Snack Foods
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Blueberry Cake|OTHER: Snacks with Cheese|OTHER: Spicy Crackers|OTHER: Glucose Solution First Repeat|OTHER: Glucose Solution Second Repeat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hypoglossal Nerve Stimulation on Cardiovascular Outcomes
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Therapeutic HGNS|DEVICE: Subtherapeutic 'Sham' HGNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue: A Randomized, Phase III Trial
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: Acupuncture and questionnaires|PROCEDURE: placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: An fMRI Study of the Effect of Intravenous Oxytocin vs. Placebo on Response Inhibition and Face Processing in Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple
Interventions: DEVICE: Scatter corrected s-DCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of NT-I7 in COVID-19 (SPESELPIS)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Double-Blind NT-I7|DRUG: Double-Blind Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contemplation-Based Intervention and Health Outcomes RCT in Lupus Patients
Status: UNKNOWN
Conditions: Lupus Erythematosus, Systemic
Interventions: BEHAVIORAL: Contemplative-Based Intervention for People Living with SLE|BEHAVIORAL: Health Enhancement Program (HEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)
Status: COMPLETED
Conditions: Hypercholesterolemia|Atherosclerosis
Interventions: DRUG: Ezetimibe + Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASPIRED-XT: ASPirin Intervention for the REDuction of Colorectal Cancer Risk -EXTension
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Aspirin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Colorectal Cancer|Pancreatic Ductal Carcinoma|Esophageal Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma|Breast Cancer|Other Solid Tumors
Interventions: DRUG: JAB-3312
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Carboplatin for Elderly Patient With Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: gemcitabine and carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery
Status: COMPLETED
Conditions: Positive-Pressure Respiration/Methods|Esophagus/Physiopathology|Pleura/Physiopathology|Gynecologic Surgical Procedures|Laparoscopy|Humans|Female
Interventions: PROCEDURE: PEEP setting based on esophageal pressure measured
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Whole-process Quality Improvement of Endovascular Treatment Basd on an AI-aided Clinical Feedback System
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: BEHAVIORAL: AI-aided clinical feedback system coupled with multi-aspect intervention basd on Behaviour Change Wheel model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frontline Clinician Psilocybin Study
Status: COMPLETED
Conditions: Burnout, Caregiver|Burnout, Professional|COVID-19|Depression|Post Traumatic Stress Disorder|Moral Injury
Interventions: DRUG: Psilocybin (Usona Institute)|DRUG: Active placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 MN rsgp120 and Bivalent AIDSVAX B/E (HIV-1 MN rgp120/A244 rgp120) in Combination With QS-21 With or Without Alum in Healthy HIV-1 Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MN rgp120/HIV-1 and A244 rgp120/HIV-1|BIOLOGICAL: QS-21|BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Epidural Analgesia Use in Pancreatic Resections
Status: COMPLETED
Conditions: Cancer of Pancreas|Cancer of the Pancreas|Pancreas Cancer|Pancreas Neoplasms|Pancreatic Cancer
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lexaptepid Pegol (NOX-H94) in ESA-hyporesponsive Anemia in Dialysis Patients
Status: COMPLETED
Conditions: Anemia|End Stage Renal Disease
Interventions: DRUG: Lexaptepid pegol (NOX-H94)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application Evaluation of Newborn Home Skin Care Management System Under the Service of "WeChat Platform+Health Care"
Status: NOT_YET_RECRUITING
Conditions: Infants
Interventions: BEHAVIORAL: intervention group (WeChat platform + healthcare)|BEHAVIORAL: control group (routine health education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Protrieve PROTECTOR Study
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Deep Venous Thrombosis
Interventions: DEVICE: Percutaneous mechanical thrombectomy (PMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single and Multiple Ascending Doses Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RBD7022
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipemia
Interventions: DRUG: RBD7022|DRUG: RBD7022|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LOAd703 Oncolytic Virus Therapy for Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: GENETIC: delolimogene mupadenorepvec|DRUG: gemcitabine|DRUG: nab-paclitaxel|BIOLOGICAL: atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bubble Nasal Continuous Positive Airway Pressure (bCPAP) in Neonatal Respiratory Distress
Status: COMPLETED
Conditions: Neonatal Respiratory Distress
Interventions: DEVICE: Bubble CPAP|OTHER: Nasal Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Dose Salbutamol on Muscle Performance
Status: UNKNOWN
Conditions: Ergogenic Effects of Salbutamol in Healthy Males
Interventions: DRUG: salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Management of Mild Cognitive Impairment Patients With Extra Virgin Olive Oil - MICOIL
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Freshly-Pressed Extra Virgin Olive Oil|COMBINATION_PRODUCT: extra virgin olive oil|OTHER: mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Clinical & Radiographic Efficiency of Manual & Pediatric Rotary Systems in Primary Root Canal Preparation
Status: COMPLETED
Conditions: Manual; Rotation|Obturation|Post Operative Pain
Interventions: PROCEDURE: pulpectomy procedure|RADIATION: Post-operative Cone Beam Computed Tomography|OTHER: Post-operative pain assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag vs. rhTPO to Increase Platelet Level After HSCT
Status: COMPLETED
Conditions: Eltrombopag|Hematopoietic Stem Cell Transplantation|Thrombocytopenia
Interventions: DRUG: Eltrombopag|DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Post-tonsillectomy Pain by Tonsil Pillars Suturing.
Status: UNKNOWN
Conditions: Post - Tonsillectomy Pain
Interventions: PROCEDURE: tonsil pillars suturing|PROCEDURE: tonsillectomy without tonsil pillars suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Albumin To Enhance Recovery After Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury|Renal Replacement Therapy|Hypotension|Critical Illness
Interventions: BIOLOGICAL: 20-25% Albumin fluid (100 mL)|OTHER: 0.9% Normal Saline (100 mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral LBH589 in Patients With Cutaneous T-cell Lymphoma and Adult T-cell Leukemia/Lymphoma
Status: TERMINATED
Conditions: Cutaneous T-Cell Lymphoma|Leukemia-Lymphoma, Adult T-Cell
Interventions: DRUG: Panobinostat (LBH589)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Radius and Capitate Shortening in Ulna Minus Variance Kienbock's Disease
Status: COMPLETED
Conditions: Avascular Necrosis of Lunate
Interventions: PROCEDURE: Henry approach; volar approach|PROCEDURE: dorsal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Inhibition and Valuation After Eating
Status: RECRUITING
Conditions: Bulimia Nervosa
Interventions: OTHER: Fasting state|OTHER: Fed state|OTHER: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL
Status: COMPLETED
Conditions: Nephrolithotomy
Interventions: PROCEDURE: Standard Percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.
Status: COMPLETED
Conditions: Chest Pain|ST Elevation Myocardial Infarction
Interventions: DEVICE: Diagnostic accuracy of Mini Relf Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN3918|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications
Status: RECRUITING
Conditions: Movement Disorders|Neurology|Parkinsons Disease
Interventions: DEVICE: Exablate Pallidotomy, Unilateral
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Didanosine|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 1303GCC: Trastuzmab & Pertuzumab With Hormonal Therapy or Chemotherapy in Women Aged 60 and Over.
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab plus Pertuzumab|DRUG: Hormonal Therapy with Anastrozole and Fulvestrant|DRUG: Chemotherapy with Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Rifaximin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain
Status: COMPLETED
Conditions: Postoperative Pain|Hip Fracture
Interventions: DEVICE: transcutaneous electric nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer
Status: TERMINATED
Conditions: Anal Cancer|Carcinoma of the Appendix|Colorectal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Liver Cancer|Nausea and Vomiting|Pancreatic Cancer|Primary Peritoneal Cavity Cancer|Small Intestine Cancer
Interventions: DRUG: palonosetron hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Characterize the Drug Levels of an Oral Contraceptive With and Without BMS-986166 in Healthy Female Participants of Childbearing Potential
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986166|DRUG: Oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer|NSCLC|NSCLC Stage IIIB|NSCLC Stage IV
Interventions: DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CP-675,206 (CTLA4-Blocking Monoclonal Antibody) Combined With Dendritic Cell Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed With Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: maximum tolerated dose of anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Zanzalintinib (XL092) + AB521 and Zanzalintinib + AB521 + Nivolumab in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Other Advanced Solid Tumors (STELLAR-009)
Status: RECRUITING
Conditions: Advanced Clear Cell Renal Cell Carcinoma or Other Advanced Solid Tumors
Interventions: DRUG: zanzalintinib|DRUG: AB521|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Interventions for Obesity
Status: RECRUITING
Conditions: Overweight|Weight Loss|Ketogenic Dieting|Obesity
Interventions: OTHER: Healthy Ketogenic Ready-to-Eat Meals|OTHER: Healthy Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calibration and Evaluation of Non-Invasive Wireless Blood Glucose Monitoring
Status: COMPLETED
Conditions: Blood Glucose, High|Blood Glucose, Low
Interventions: DEVICE: Actxa BGM Tracker (GLO2)|DEVICE: SVT In-Ear Prototype (IEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lung Ultrasound Versus Dynamic Lung Compliance to Detect the Optimum PEEP After Alveolar Recruitment for Patients Undergoing Laparoscopic Gastric Sleeve Surgery
Status: COMPLETED
Conditions: Mechanical Ventilation During Anesthesia
Interventions: DEVICE: anesthesia ventilator machine|DEVICE: lung ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changes in Body Composition After EPA Supplementation in Head and Neck Patients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DIETARY_SUPPLEMENT: EPA supplementation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic HBV Infection
Interventions: DRUG: HS-10234|DRUG: TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-bout Handgrip Exercise for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Video about exercise|BEHAVIORAL: App about exercise|BEHAVIORAL: Leaflet about exercise|BEHAVIORAL: Video about diet|BEHAVIORAL: App about diet|BEHAVIORAL: Leaflet about diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exemestane + Celecoxib vs Exemestane + Placebo in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: placebo|DRUG: Celecoxib|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Intermediate-dose CTX+ G-CSF Plus or Not rhTPO for PB CD34+ Cells Mobilization in MM Patients
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: rhTPO|DRUG: CTX|DRUG: -CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Disorders|Sleep Initiation and Maintenance Disorders|Dyssomnias|Mental Disorders|Nervous System Diseases
Interventions: BEHAVIORAL: Tai Chi Chih|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Sitravatinib as Maintenance Therapy for ES-SCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer, Small Cell
Interventions: DRUG: Tislelizumab|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Contextually Cued PA Habits
Status: COMPLETED
Conditions: Exercise
Interventions: BEHAVIORAL: Non-cue-contingent weekly incentives|BEHAVIORAL: Cue-contingent weekly incentives|BEHAVIORAL: Habit Coaching|BEHAVIORAL: App use instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Motor Imagery Techniques in the Management of Acute Lateral Ankle Sprains in Soccer Players
Status: COMPLETED
Conditions: Ankle Sprains
Interventions: OTHER: Motor Imagery Techniques|OTHER: Conventional Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Young People Aged 18-25 With Depression or Anxiety Mood Participate in an LLM-based Digital Dialogue Intervention Study
Status: COMPLETED
Conditions: LLM-based AI Dialogue Bot|Depression|Anxiety
Interventions: OTHER: Douyin Xinqing AI dialog bot|OTHER: Douyin Xinqing AI dialog bot for delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase I Trial of LMP2 Antigen-specific TCR T-cell Therapy for Recurrent and Metastatic NPC Patients
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: LMP2 Antigen-specific TCR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperosmolality and Acute Kidney Injury After Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury|Osmolality Disturbance|Cardiopulmonary Bypass
Interventions: DRUG: HighOsmo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored, wEb-based, Psychosocial and Physical Activity Self-Management PrOgramme
Status: COMPLETED
Conditions: Cancer of Prostate|Anxiety
Interventions: OTHER: TEMPO|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Multi-Component Interventions on High Risk COPD Population
Status: NOT_YET_RECRUITING
Conditions: Multimorbidity|Population Medicine|Chronic Obstructive Pulmonary Disease
Interventions: COMBINATION_PRODUCT: Multi-component intervention package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Between Bupivacaine and Bupivacaine- Dexamethasone QLB for Postoperative Analgesia
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Bupivacaine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: 1.2% Rosuvastatin Gel As A Local Agent In Smokers With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: SRP plus Rosuvastatin gel|DRUG: SRP plus placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Cardiovascular Risk Outpatient Management in South Asians Using Digital Health Technology
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Insulin Resistance|PreDiabetes|Diabetes|Coronary Artery Disease|Hypertension|Prehypertension|Dyslipidemias
Interventions: BEHAVIORAL: Use of HealthPals (Telemedicine supported by digital health platform)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION