pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Trial Evaluating Feasibility and Quality of Life of Second Look Laparoscopy With Hyperthermic Intraperitoneal Chemotherapy
Status: RECRUITING
Conditions: Ovarian Epithelial Cancer Stage I|Ovarian Epithelial Cancer Stage II|Ovarian Epithelial Cancer Stage III|Stage I Fallopian Tube Cancer|Stage II Fallopian Tube Cancer|Stage III Fallopian Tube Cancer|Peritoneal Carcinoma
Interventions: PROCEDURE: Second look laparoscopy reassessment surgery (SLLRS)|DRUG: HIPEC with Carboplatin|OTHER: FACT-O Quality of Life Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low-frequency rTMS on Motor Function in PD Patients With Freezing of Gait
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Low-frequency repetitive Transcranial Magnetic Stimulation|DEVICE: rTMS maintenance|DEVICE: Sham|DEVICE: Sham maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Twice Daily Dosing (EDGE)
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: DRUG: Eliglustat tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis
Status: UNKNOWN
Conditions: Chronic Sinusitis, Ethmoidal|Chronic Sinusitis - Ethmoidal Anterior|Chronic Sinusitis|Chronic Sinusitis - Ethmoidal, Posterior|Chronic Sinusitis, Sphenoidal|Chronic Sinusitis - Frontoethmoidal|Nasal Polyps|Nasal Polyp - Posterior
Interventions: DRUG: gel loaded with steroids (momentasone)|DRUG: gel loaded with antibiotic (Levofloxacin)|DRUG: gel loaded with both steroids and antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Cognitive Impairments
Interventions: DRUG: Lisdexamfetamine Dimesylate|DRUG: Placebo "30, 50 or 70 mg"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Living After a Rare Cancer of the Ovary: Chronic Fatigue, Quality of Life and Late Effects of Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Germ Cell Tumor|Sex Cord Stromal Tumor|Malignant Non-epithelial Ovarian Tumors
Interventions: OTHER: Self-questionnaires of living conditions and quality of life|DIAGNOSTIC_TEST: Cardiac, pulmonary, auditory and biological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TRIal For Efficacy of Capre on hyperTriglyceridemiA
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: CaPre (TM)|OTHER: Placebo|DRUG: CaPre (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
Status: RECRUITING
Conditions: Colorectal Cancer|Pancreatic Cancer|Esophageal Cancer|Gastric Cancer
Interventions: DRUG: LUM015|DEVICE: LUM 2.6 Imaging Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Tumor, Breast|Breast Tumor|Malignant Neoplasm of Breast|Mammary Cancer|Mammary Neoplasm|Mammary Neoplasms, Human|Neoplasm, Breast
Interventions: GENETIC: HTR2 T Cells|GENETIC: HTR2 T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour: a Prospective Cohort Study
Status: UNKNOWN
Conditions: Urinary Tract Infection in Pregnancy|Urinary Tract Infection Following Delivery|Catheter Infection
Interventions: OTHER: Catheter insertion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Randomised Controlled Trial of a Health Champion Intervention
Status: UNKNOWN
Conditions: Schizophrenia|Bipolar Disorder|Major Depressive Disorder
Interventions: OTHER: Health Champions intervention|OTHER: Control group-treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunogenicity and Safety Study of a Single Prime-Boost Vaccination Schedule With a H5N1 Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza|Avian Influenza
Interventions: BIOLOGICAL: Influenza vaccine (whole virion, Vero cell derived)|BIOLOGICAL: Influenza vaccine (whole virion, Vero cell derived)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial: Adjuvant Low-dose Ipilimumab + Nivolumab After Resection of Melanoma Macrometastases
Status: COMPLETED
Conditions: Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: DRUG: nivolumab|DRUG: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Durvalumab Alone or in Combination With Novel Agents in Resectable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Resectable|Early-stage|NSCLC
Interventions: DRUG: Durvalumab|COMBINATION_PRODUCT: Oleclumab|COMBINATION_PRODUCT: Monalizumab|COMBINATION_PRODUCT: Danvatirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Manipulations on Portal Venous Flow
Status: COMPLETED
Conditions: Breathing Exercises|Manipulation, Osteopathic|Physical Therapy|Ultrasonography|Portal Vein
Interventions: PROCEDURE: Liver pumping and Spinal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Open-label Extension Study Evaluating 6-week Treatment Cycles of Rozanolixizumab in Pediatric Study Participants With Generalized Myasthenia Gravis
Status: NOT_YET_RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: rozanolixizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: TLL-018|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Online Mindfulness Therapy for Pandemic Fatigue and Resilience in COVID-19 Nurses
Status: COMPLETED
Conditions: Mindfulness|Nurses in COVID-19|Pandemic Fatigue|Resilience
Interventions: OTHER: 6-week online mindfulness course
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Lateral Cephalometric and Cone Beam CT Measurements in Mandibular Symphysis
Status: COMPLETED
Conditions: Measurements in Mandibular Symphysis
Interventions: RADIATION: LC images|RADIATION: CBCT images
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: DEVICE: on-line hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pazopanib or Pemetrexed and Crizotinib in Advanced Cancer
Status: TERMINATED
Conditions: Advanced Cancers
Interventions: DRUG: Crizotinib (Xalkori)|DRUG: Pazopanib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Perioperative Camrelizumab Combined With Chemotherapy in Patients With Resectable ESCC
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: A：non-pCR patients|DRUG: B：non-pCR patients|DRUG: A：pCR patients|DRUG: B：pCR patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Status: UNKNOWN
Conditions: Patient Depression, Anxiety, Stress and Pain
Interventions: BEHAVIORAL: Holy Quran Recital effect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of a Modular Extracorporeal Circulation Circuit
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Valve Disease|Mitral Valve Disease|Aortic Aneurysm
Interventions: DEVICE: Modular Cardiopulmonary Bypass Circuit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Regorafenib After Sorafenib in Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disposable Versus Reusable drApes and Gowns for Green OperatiNg Theatres
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection
Interventions: OTHER: Intervention: Reusable drapes and gowns|OTHER: Comparator: Disposable (single-use) drapes and gowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preoperative Gum Chewing for Different Durations to Prevent Sore Throat After Endotracheal Intubation
Status: COMPLETED
Conditions: Gum Chewing|Sore Throat|Endotracheal Intubation|Randomized Controlled Trial
Interventions: DIETARY_SUPPLEMENT: Gum chewing for 2 minutes|DIETARY_SUPPLEMENT: Gum chewing for 4 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FLT3 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Interventions: DRUG: gilteritinib|DRUG: LoDAC (Low Dose Cytarabine)|DRUG: MEC (Mitoxantrone, Etoposide, Cytarabine)|DRUG: FLAG (Granulocyte colony-stimulating factor (G-CSF), Fludarabine, Cytarabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Constraint Induced Movement Therapy and Mirror Therapy
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: Constraint Induced Movement Therapy|OTHER: Mirror therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Polarized and Pyramidal Training Combined With or Without Mindfulness in Amateur Runners
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Polarized training intensity distribution (TID) and mental training using mindfulness|BEHAVIORAL: Pyramidal training intensity distribution (TID) and mental training using mindfulness|BEHAVIORAL: Polarized training intensity distribution (TID) without mindfulness|BEHAVIORAL: Pyramidal training intensity distribution (TID) without mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mucolox® and Clonazepam in Treatment of Burning Mouth Syndrome
Status: WITHDRAWN
Conditions: Burning Mouth Syndrome
Interventions: DRUG: Clonazepam mixed with Mucolox®|DRUG: Mucolox® alone|DRUG: Clonazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Digital Sleep Therapy for Older Adults With Cognitive Impairment
Status: RECRUITING
Conditions: Insomnia Type; Sleep Disorder|Cognitive Impairment
Interventions: OTHER: SleepFix mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic Infections
Status: COMPLETED
Conditions: Apical Periodontitis|Postoperative Pain|Cytokine Levels
Interventions: DEVICE: Distilled water irrigation kept at 2.5°C degree|DEVICE: Distilled water irrigation kept at room temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D AND Glucose Handling Evaluated by Glucose Clamp
Status: COMPLETED
Conditions: Insulin Sensitivity|Intraocular Pressure
Interventions: DRUG: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telbivudine Versus the Combination of Telbivudine and Valtorcitabine in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: telbivudine|DRUG: valtorcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Pimecrolimus ointment|DRUG: Adcortyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Standard Normothermia Protocol On Surgical Site Infections
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: OTHER: Prewarming and perioperative warming with Forced Air Warming device and its blankets.|DEVICE: Forced Air Warming blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine After Cardiac Surgery for Prevention of Delirium
Status: COMPLETED
Conditions: ICU Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Highly Purified Menotropin (HP-hMG) Versus Recombinant FSH (rFSH) Plus Recombinant LH (rLH) in Intrauterine Insemination Cycles in Women ≥35 Years: a Prospective Randomized Trial.
Status: COMPLETED
Conditions: Female Infertility
Interventions: DRUG: Meropur 150 a day|DRUG: Gonal-f 150 plus Luveris 150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Added in Ultrasound-guided Transversus Abdominis Plain Block for Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: TAP Block and Dexamethasone|OTHER: TAP Block and saline|DRUG: TAP Block and Dexamethasone i.v.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cat-PAD Exposure Chamber Study
Status: COMPLETED
Conditions: Cat Allergy
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Cat-PAD|BIOLOGICAL: Cat-PAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Rehabilitation Versus Psychoeducation in Psychosocial Functioning of Borderline Personality Disorder
Status: COMPLETED
Conditions: Neuropsychology
Interventions: OTHER: cognitive remediation|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vertical Scar Versus Inferior Pedicle Reduction Mammoplasty
Status: COMPLETED
Conditions: Breast Hypertrophy
Interventions: RADIATION: Vertical scar versus inferior pedicle reduction mammoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty
Status: RECRUITING
Conditions: Joint Diseases|Joint Pain
Interventions: OTHER: SSNB + IPACK|OTHER: FNB + IPACK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Atozet 10/40 mg or 10/80 mg|DRUG: Lipitor 40 mg or 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of DPP4 Inhibitor on Vasclular Healing
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin|DRUG: Non DPP-4 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treximet in Acute Migraine Headache: Assessing Cognitive Function
Status: UNKNOWN
Conditions: Migraine Headache|Cognitive Impairment
Interventions: DRUG: Treximet|DRUG: Migraine rescue medication of choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Lubricant Investigation in Men to Inhibit Transmission of HPV Infection
Status: TERMINATED
Conditions: Human Papillomavirus Infection
Interventions: OTHER: Carrageenan-based gel|OTHER: Control gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Ustekinumab to Evaluate a "Subject-tailored" Maintenance Dosing Approach in Subjects With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ustekinumab 45 mg|DRUG: Ustekinumab 90 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subarachnoid Bupivacaine in Obese Patients Undergoing Cesarean Delivery
Status: COMPLETED
Conditions: Anesthesia, Obstetrical
Interventions: DRUG: Bupivacaine 5 mg|DRUG: Bupivacaine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Motivational Interviewing on Improving Care for Type 2 Diabetes Mellitus Patients in China
Status: COMPLETED
Conditions: Diabete Type 2
Interventions: BEHAVIORAL: Motivational interviewing (MI)-based patient empowerment program (PEP)|BEHAVIORAL: Traditional lecture style health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech
Status: RECRUITING
Conditions: Aphasia|Apraxia of Speech|Dysarthria
Interventions: BEHAVIORAL: Multimodal Intensive Rehabilitation of Aphasia and Apraxia of Speech
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Analgesic Reduction Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use
Interventions: DRUG: opioid-containing analgesic|DRUG: two over-the-counter analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Aquatic Exercise on Fatigue, Neuropathy and Quality of Life Among Cancer Patients
Status: RECRUITING
Conditions: Colon Cancer|Breast Cancer
Interventions: OTHER: Water exercise group|OTHER: Land exercise group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Psycho-educational Training in Undergraduate Students at the University of Granada (Spain)
Status: COMPLETED
Conditions: Empathy|Compassion|Attention|Psychological Distress|Life Stress|Anxiety|Creativity|Emotional Intelligence
Interventions: BEHAVIORAL: The MBSR program|BEHAVIORAL: Más Presente, the UGRComp program|OTHER: Neuro-muscular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.
Status: TERMINATED
Conditions: Metastatic Solid Tumors|Locally Advanced Solid Tumors
Interventions: DRUG: OBI-888|DRUG: OBI-888|DEVICE: Globo H IHC Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of the HERCULINK 14 Stent to Treat Renal Artery Disease
Status: TERMINATED
Conditions: Renal Artery Obstruction
Interventions: DEVICE: Stenting: Renal Artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparıson Of PENG Block wıth Intra-articular And Quadratus Lumborum Block İn Primary Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthropathy
Interventions: PROCEDURE: Group A|PROCEDURE: Group B|PROCEDURE: Group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copenhagen Head Injury Ciclosporin (CHIC) Study
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: NeuroSTAT 5 mg/kg/day|DRUG: NeuroSTAT 10 mg/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Antibiotic Treatment Following Implantation of Cardiac Electronic Device on Patient's Outcome
Status: UNKNOWN
Conditions: Infection, Bacterial|Pacemaker Complication
Interventions: DRUG: cefalexin 500 mg qid or roxithromycin 150 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PK & Tolerability of CNV1014802 in Young and Elderly Healthy Volunteers
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: CNV1014802|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obatoclax Mesylate and Topotecan Hydrochloride in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer or Advanced Solid Tumors
Status: COMPLETED
Conditions: Recurrent Small Cell Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: obatoclax mesylate|DRUG: topotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TLESR-impedance Study in Patients
Status: COMPLETED
Conditions: Reflux Episodes
Interventions: DRUG: AZD3355|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of 6-months of Resistance Training on Brain and Muscle Health in Older Adults With MCI
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Older Adults at High Risk for MCI
Interventions: BEHAVIORAL: Resistance exercise training|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Immune Reactivity of Biofilms in Vaginal Mesh Erosion.
Status: UNKNOWN
Conditions: Uterine Prolapse|Urinary Incontinence|Fecal Incontinence
Interventions: PROCEDURE: excision of the protruding mesh and its surrounding vaginal tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Tumor Samples From Patients With Ependymoma Treated on the Children's Oncology Group ACNS0121 Trial
Status: COMPLETED
Conditions: Childhood Infratentorial Ependymoma|Childhood Supratentorial Ependymoma|Newly Diagnosed Childhood Ependymoma
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Inflexibility of the Heart as a Predictor of Occurrence of Heart Failure in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: MRI in patients|DIAGNOSTIC_TEST: MRI in healthy volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Effectiveness Trial to Evaluate Protection of Children and Pregnant Women by Influenza Vaccine in Rural Bangladesh
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza Viral Infections
Interventions: BIOLOGICAL: Inactivated influenza vaccine|BIOLOGICAL: Inactivated polio vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Delayed and Extended Release Formulation of Dextroamphetamine Sulfate (HLD100) in Children With ADHD
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: HLD100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect on Blood Cells, Known as Platelets, Using Prasugrel vs Clopidogrel in Patients With the Heart Problem Acute Coronary Syndrome (ACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Innovative Mobile Health Intervention to Improve Self-care in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: iCardia4HF|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of EGT0001442 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: EGT0001442|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steno2tech - Continuous Glucose Monitoring and Type 2 Diabetes.
Status: COMPLETED
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: CGM|BEHAVIORAL: training course|BEHAVIORAL: Peer-support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teletechnology-assisted Home-based Exercise Program for Severe COVID-19
Status: RECRUITING
Conditions: COVID-19|Telerehabilitation
Interventions: BEHAVIORAL: Teletechnology-assisted home-based pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans
Status: COMPLETED
Conditions: Distress|Anxiety|Depression|Postconcussive Symptoms
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Present Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lemon Verbena Extract Oxidative Stress and Muscle Damage
Status: COMPLETED
Conditions: Muscle Injury|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Lvemon verbena extract|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Remimazolam Tosilate for Sedation in Non-intubated Diagnostic and Therapeutic Procedures
Status: NOT_YET_RECRUITING
Conditions: Sedation in Non-intubated Diagnostic and Therapeutic Procedures
Interventions: DRUG: Remimazolam Tosilate for Injection|DRUG: Remimazolam Tosilate for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of AMZ002 Treatment, Compared With Vigabatrin in Participants With Infantile Spasms
Status: WITHDRAWN
Conditions: Spasms, Infantile
Interventions: DRUG: AMZ002 injectable solution, 0.5mg/mL|DRUG: Vigabatrin, oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A SU011248 Expanded Access Protocol for Systemic Therapy of Patients With Metastatic Renal Cell Carcinoma Who Are Ineligible for Participation in Other SU011248 Protocols But May Derive Benefit From Treatment With SU011248
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Degrees of Freedom Post-stroke for the Recovery of the Upper Limb
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Training with restriction of the DoF|BEHAVIORAL: Training without restriction of the DoF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate 100mcg via ACCUHALER/DISKUS|DRUG: GSK2190915 100mg|DRUG: GSK2190915 10mg|DRUG: GSK2190915 300mg|DRUG: GSK2190915 30mg|DRUG: Montelukast 10mg|DRUG: Placebo GSK2190915 one tablet|DRUG: Placebo montelukast|DRUG: Placebo fluticasone propionate via ACCUHALER/DISKUS|DRUG: Placebo GSK2190915 two tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Confirmatory Study in Erythropoietic Protoporphyria (EPP)
Status: COMPLETED
Conditions: Erythropoietic Protoporphyria
Interventions: DRUG: Afamelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of UX003 Recombinant Human Beta-Glucuronidase (rhGUS) Enzyme Replacement Therapy in Subjects With Mucopolysaccharidosis Type 7, Sly Syndrome (MPS 7)
Status: COMPLETED
Conditions: Sly Syndrome|MPS VII|Mucopolysaccharidosis|Mucopolysaccharidosis VII
Interventions: DRUG: UX003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Status: RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Radial Extracorporeal Shock Wave Therapy in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: ESWT|DEVICE: Sham-ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Spectroscopy and Testicular Torsion in Children
Status: COMPLETED
Conditions: Diagnostic Test|NIRS|Testicular Torsion|Diagnosis|Child
Interventions: OTHER: near-infrared spectroscopy (NIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea
Status: COMPLETED
Conditions: Travelers' Diarrhea
Interventions: DRUG: Rifaximin and loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chest Mobility, Strength, Physical Activity and Quality of Life in Parkinson's Patients With Post-COVID-19
Status: RECRUITING
Conditions: COVID-19 Respiratory Infection|Parkinson Disease
Interventions: OTHER: Physical Evaluations of post-COVID-19 individuals|OTHER: Physical Evaluations of non-post-COVID-19 individuals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Placental MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Alzheimer's
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease, Early Onset|Dementia|Alzheimer Disease
Interventions: PROCEDURE: Device Implantation- Boston Scientific, VERCISE GENUS™ system|DEVICE: DBS Stimulation - Boston Scientific, VERCISE GENUS™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of SHR-1918 in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipemia
Interventions: DRUG: SHR-1918|DRUG: SHR-1918 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of BIA 5-1058 on the Steady State Pharmacokinetics of Treprostinil
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: BIA 5-1058|DRUG: treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical)
Status: UNKNOWN
Conditions: Vestibular Function Tests
Interventions: DEVICE: Computerized Rotational Head Impulse Test ( crHIT)-Vertical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Ertapenem Sodium (MK-0826) Following Colorectal Surgery in Chinese Adults (MK-0826-056)
Status: COMPLETED
Conditions: Infection|Surgical Site Infection
Interventions: DRUG: ertapenem sodium|DRUG: ceftriaxone sodium|DRUG: placebo to metronidazole|DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing Neuropsychiatric Symptoms Including Depression, Anxiety, Irritability, and Suicidal Thoughts or Behavior in Subjects Quitting Smoking on Varenicline Tartrate or Placebo
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Prospective Study of Quality of Life in Unresectable TNM Stage III NSCLC (OBSTINATE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: Quality of Life Questionnaire-Core 30 (QLQ-C30)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Decitabine for Treatment of Older Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I
Status: RECRUITING
Conditions: Mucopolysaccharidosis IH/S|Mucopolysaccharidosis IS
Interventions: BIOLOGICAL: Autologous Plasmablasts (B cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Multiple Myeloma|Smoldering Multiple Myeloma (SMM)|Monoclonal Gammopathy of Undetermined Significance
Interventions: DRUG: Curcumin plus Piperine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Biological Availability|Healthy Participants
Interventions: DRUG: Paxlovid|DRUG: Paxlovid|DRUG: Nirmatrelvir/ritonavir|DRUG: Nirmatrelvir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser Versus Vitrectomy Versus Intravitreal Triamcinolone Injection for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Diabetes
Interventions: PROCEDURE: Vitrectomy|DRUG: Intravitreal triamcinolone injections|PROCEDURE: Laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Abdominoplasty.
Status: RECRUITING
Conditions: Abdominal Wall Defect|Hemorrhage|Bleeding
Interventions: DRUG: Placebo|DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors
Status: RECRUITING
Conditions: Recurrent Diffuse Intrinsic Pontine Glioma|Recurrent Malignant Glioma|Recurrent Medulloblastoma|Recurrent Primary Central Nervous System Neoplasm|Refractory Diffuse Intrinsic Pontine Glioma|Refractory Malignant Glioma|Refractory Medulloblastoma|Refractory Primary Central Nervous System Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|DRUG: Savolitinib|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria
Status: RECRUITING
Conditions: Malaria
Interventions: BIOLOGICAL: BNT165e|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Electromagnetic Navigation for Peripheral Pulmonary Lesions
Status: COMPLETED
Conditions: Peripheral Lung Lesions
Interventions: DEVICE: Olympus BF-180 bronchoscope (standard adult)|DEVICE: Veran Spinview Thoracic Navigation System|DEVICE: Olympus UM-S20-17S|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 5-Cog Battery for Detecting Cognitive Impairment and Dementia
Status: COMPLETED
Conditions: Dementia|Cognitive Impairment|Mild Cognitive Impairment|Neurocognitive Disorders
Interventions: OTHER: 5-Cog|OTHER: Health Literacy & Grip Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: High Dose Fluconazole in Cutaneous Leishmaniasis in Bahia and Manaus
Status: TERMINATED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Fluconazole|DRUG: Meglumine Antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: [177Lu]Ludotadipep 3.7 GBq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of EPAP and Noninvasive Ventilation on Pulmonary Function and Lung Regional Ventilation on Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery|Obesity|Physical Therapy Modalities
Interventions: OTHER: Noninvasive Ventilation|OTHER: Expiratory Positive Air Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of FES-PET Imaging as a Tool to Detect a Possible Reversion of Estrogen Receptor (ER)-α Status in Patients With Metastatic Breast Cancer HER2 + and ERα Neg Treated With Trastuzumab + Pertuzumab + Taxane.
Status: TERMINATED
Conditions: HER2-positive Breast Cancer
Interventions: OTHER: 2 FES-PET Imaging will be performed:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low Dose of IL-2 In Acute Respiratory DistrEss Syndrome Related to COVID-19
Status: COMPLETED
Conditions: COVID 19
Interventions: DRUG: 1: ILT101|DRUG: 2: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Simvastatin's Potential Role in Therapy
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION