pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of the Efficacy of a Treatment by One Single Dose of Rituximab (375mg/m2 ) in the Prevention of the Epstein Barr Virus (EBV) Primary Infection and Post-transplant Lymphoproliferative Disorder in Adult EBV Seronegative Patients Who Received an EBV Seropositive Kidney Allograft
Status: RECRUITING
Conditions: Epstein-Barr Virus Infections
Interventions: DRUG: Rituximab|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interactions Between Striatum and Cerebellum in ADCY5 and PRRT2 Dystonias
Status: UNKNOWN
Conditions: Dystonia
Interventions: OTHER: transcranial magnetic stimulation of the cerebellum
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intense Pulsed Light in Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Intense Pulsed Light therapy|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simethicone and Bowel Preparation in Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation
Interventions: DRUG: Simethicone 180Mg Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of the Cardiapex Percutaneous Trans-apical Access and Closure System
Status: TERMINATED
Conditions: Transapical Transcatheter Aortic Valve Implantation
Interventions: DEVICE: Cardiapex device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: An Evaluation of Pentoxifylline in HIV-Positive Persons With Symptomatic HIV Infection and a Karnofsky Score > 40 Percent and < 100 Percent
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Long-term Evaluation of Primary Trapeziectomy and Placement of a RegJoint Implant in the Treatment of Rhizarthrosis
Status: COMPLETED
Conditions: Rhizarthrosis
Interventions: DEVICE: Regjoint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Patients With Metastatic and/or Advanced Renal Cell Carcinoma, Treated With Sunitinib/Axitinib.
Status: COMPLETED
Conditions: Carcinoma|Renal Cell
Interventions: DRUG: Sunitinib|DRUG: Axitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola)
Status: WITHDRAWN
Conditions: Ebola Virus Disease
Interventions: DRUG: Best Supportive Care|DRUG: Best Supportive Care + Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension
Status: UNKNOWN
Conditions: Thalassemia
Interventions: DRUG: L-arginine|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Variation of the Intestinal Microbiota and the Integrity of the Intestinal Barrier in Patients With M.D.R. Germ-induced Pneumonia Undergoing Enteral Nutrition
Status: NOT_YET_RECRUITING
Conditions: Multi Drug Resistant|Dysphagia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Ivabradine on Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy (NIDCM) on Current Medical Therapy Era
Status: ACTIVE_NOT_RECRUITING
Conditions: Dilated Cardiomyopathy|Ventricular Remodeling|Heart Failure, Reduced Ejection Fraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Astragalus for Non-motor Symptoms of α-Synucleinopathy
Status: RECRUITING
Conditions: Parkinsonism
Interventions: BEHAVIORAL: Physical therapy group|DRUG: Astragalus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study In Patients Who Will Undergo Surgical Removal Of Non-Small Cell Lung Cancer To Evaluate Molecular Changes That Occur In Tumor Tissue After Short Term Exposure To PF-00299804
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Healthy Relationships and Economic Pathways
Status: TERMINATED
Conditions: Adolescent Relationship Abuse|Sexually Transmitted Infections|Pregnancy (Unwanted)|Violence|Intentional Injury
Interventions: BEHAVIORAL: Healthy Relationships Education (HRE)|BEHAVIORAL: HRE+Technology Bootcamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture and Moxa: A Randomized Clinical Trial for Chronic Diarrhea in HIV Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chloride Transfer During Continuous Renal Replacement Therapy in the Intensive Care Unit: a Prospective Observational Cohort Study
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DEVICE: Continuous veno-venous hemofiltration|DEVICE: Continuous veno-venous hemodialysis|DEVICE: Continuous veno-venous hemodiafiltration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z
Status: UNKNOWN
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: MVA-EBO Z|BIOLOGICAL: ChAd3-EBO Z
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microendoscopic Discectomy Vs Transforaminal Endoscopic Lumbar Discectomy Vs Open Discectomy
Status: UNKNOWN
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: open discectomy|PROCEDURE: microendoscopic discectomy|PROCEDURE: transforaminal endoscopic lumbar discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient Satisfaction With Home Induction and In-patient Induction.
Status: COMPLETED
Conditions: Induced; Birth|Pregnancy
Interventions: OTHER: Preliminary search in the patient's file|OTHER: A posteriori research in the patient's file|OTHER: First questionnaire : choice of induction method reason for choice|OTHER: Second questionnaire : experience of induction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Psychosocial Transitional Group Pragmatic Trial
Status: RECRUITING
Conditions: Amputation|Psychotherapy, Group|Mental Health
Interventions: BEHAVIORAL: Supportive-expressive group therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiforme
Status: RECRUITING
Conditions: Anaplastic Oligoastrocytoma|Glioblastoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Activated Recombinant Human Factor VII in Haemophilia Patients With Inhibitors During and After Major Surgery
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: activated recombinant human factor VII|DRUG: activated recombinant human factor VII|OTHER: factor IX|DRUG: factor VIII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)
Status: COMPLETED
Conditions: Stargardt's Macular Dystrophy
Interventions: BIOLOGICAL: hESC-RPE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
Status: COMPLETED
Conditions: Cardiovascular Disease|Hypercholesterolemia|Obesity|Fatty Liver
Interventions: OTHER: American Heart Association Diet|OTHER: Reduced Fat Vegan Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: OTHER: Measurement of carbon monoxide level in exhaled breath
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Analysis of Cetuximab Plus Irinotecan in Patients With Wild-type KRAS Without Regard to Epidermal Growth Factor Receptor (EGFR) Expressions
Status: COMPLETED
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Cetuximab, irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Open-angle Glaucoma
Interventions: DRUG: Timolol maleate Ophthalmic Solution 0.5% BID|DRUG: AR-13324 Ophthalmic Solution 0.02%|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of OpeN VErsus RoboTic Partial Nephrectomy
Status: WITHDRAWN
Conditions: Renal Masses
Interventions: PROCEDURE: Robotic Partial Nephrectomy|PROCEDURE: Open Partial Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dry Needling for Cervicogenic Headache
Status: UNKNOWN
Conditions: Headache
Interventions: OTHER: Dry Needling|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial to Evaluate the Predictive Accuracy of a Gene Expression for Stage I-II Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Paclitaxel|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Constructive Debriefing on Procedural Skills and Satisfaction of Nursing Students in Low Fidelity Context. A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Procedural Skill. Learning
Interventions: OTHER: constructive debriefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Carcinoma, Pancreatic Ductal|Pancreatic Cancer|Pancreatic Disease
Interventions: BIOLOGICAL: AGS-1C4D4|BIOLOGICAL: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tobemstomig + Nab-Paclitaxel Compared With Pembrolizumab + Nab-Paclitaxel in Participants With Previously Untreated, PD-L1-Positive, Locally-Advanced Unresectable or Metastatic Triple-Negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tobemstomig|DRUG: Pembrolizumab|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of VR and Buzzy on Pain and Anxiety
Status: COMPLETED
Conditions: Procedural Pain|Procedural Anxiety|Pain|Children, Only
Interventions: OTHER: Buzzy Group|OTHER: Virtual Realitiy-VR Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Flow Nasal Cannula in Immunocompromised Patient With Acute Respiratory Failure
Status: UNKNOWN
Conditions: High Flow Nasal Cannula|Non Invasive Ventilation|Acute Respiratory Failure
Interventions: DEVICE: High Flow Nasal Cannula|DEVICE: Non Invasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Multicenter Post Approval Study to Evaluate the Long-term Safety and Efficacy of the Resolute Integrity in the Japanese All-comers Patients With Coronary Artery Disease (PROPEL)
Status: COMPLETED
Conditions: Coronary Artery Disease|Drug-eluting Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stress Free Now in a Corporate Call Center
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Web-based Stress Management Program (WSM)|BEHAVIORAL: Group Support (WSMg1)|BEHAVIORAL: Clinical Expert Support (WSMg2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hallux Limitus Treated With Dynamic Splinting: A Randomized, Controlled Trial
Status: COMPLETED
Conditions: Hallux Limitus
Interventions: DEVICE: Metatarsophalangeal Extension Dynasplint System|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Phase 2 Study of VEGF Trap as a Single Agent in Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Leukemia
Interventions: BIOLOGICAL: VEGF Trap|PROCEDURE: Bone marrow biopsy|PROCEDURE: bone marrow aspiration|PROCEDURE: Venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Soft Contact Test Lens A|DEVICE: Soft Contact Test Lens C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PBMT on Muscular Performance and Recovery in Different Time-points
Status: COMPLETED
Conditions: Phototherapy
Interventions: DEVICE: Photobiomodulation Therapy (PBMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Necitumumab and Abemaciclib in Participants With Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Neoplasm Metastasis
Interventions: DRUG: Necitumumab|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Injection of Epo After Myocardial Infarct "Intra-CO-EpoMI"
Status: COMPLETED
Conditions: Acute Myocardial Infarct
Interventions: DRUG: Darbepoetin alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Assisted Hatching on Vitrified Embryo Transfer Clinical Outcome
Status: TERMINATED
Conditions: Complications Associated With Artificial Fertilization|Placenta; Implantation|Pregnancy
Interventions: DEVICE: Mechanical Assisted Hatching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: zolbetuximab|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Perfusion Index an Indicator of Block Success in Ultrasound-guided Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Perfusion Index
Interventions: PROCEDURE: Infraclavicular nerve block|PROCEDURE: Without nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
Status: COMPLETED
Conditions: Insulin Resistance|Chronic Heart Failure
Interventions: DRUG: Metformini hydrochloridum (Siofor 1000 tbl, Berlin)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AML
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|AML, Childhood|Relapsed Pediatric AML|Refractory Pediatric AML
Interventions: DRUG: ELU001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECTS OF THE YOGA-BASED PROGRAM ON THE SOCIAL EMOTIONAL AND PSYCHOLOGICAL HEALTH OF CHILDREN, SOCIAL SKILLS AND QUALITY OF LIFE
Status: NOT_YET_RECRUITING
Conditions: Preschool|Yoga|Massage|Psychological Well-Being|Quality of Life
Interventions: BEHAVIORAL: Music Activities, Yoga, Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Urinary Tract Infection Study With the Antibiotic Levofloxacin Given at a Higher Dose Over a Shorter Period of Time
Status: TERMINATED
Conditions: Complicated Urinary Infection
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on the Failure Rates of Metallic and Ceramic Orthodontic Brackets
Status: COMPLETED
Conditions: Dental Malocclusion
Interventions: OTHER: Fixed orthodontic treatment with stainless steel brackets|OTHER: Fixed orthodontic treatment with ceramic brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Chidamide Combined With CAT-T or TCR-T Cell Therapy on HIV-1 Latent Reservoir
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BIOLOGICAL: Chidamide with CAR-T or TCR-T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of GSK Biological Pandemic Candidate Influenza Vaccine (H1N1) in Children
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK pandemic vaccine GSK2340272A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasms, Hormone-dependent
Interventions: DRUG: atamestane|DRUG: toremifene|DRUG: letrozole|DRUG: aromatase inhibition|PROCEDURE: hormone therapy|PROCEDURE: endocrine therapy|PROCEDURE: antiestrogen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: En Bloc Transurethral Resection of Non-muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: PROCEDURE: En Bloc resection|PROCEDURE: Conventional TURB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Interdisciplinary Pain Program Among Patients With Chronic Pain and Frequent Emergency Department Visits
Status: COMPLETED
Conditions: Chronic Pain|Peer Review, Health Care|Interdisciplinary Communication
Interventions: OTHER: CIPAP Program|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Determine the Fasting Bioequivalence of Reformulated OXY Tablets and Original OxyContin® (OXY) Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Reformulated OXY (oxycodone HCl)|DRUG: Original OxyContin® (OXY) (oxycodone HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Oral Salt Supplementation on Physical Performance During a Half-ironman
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DIETARY_SUPPLEMENT: Salt administration|DIETARY_SUPPLEMENT: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Botulinum Toxin Injection for the Management of BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: botulinum toxin type A (BoNT/A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-Frequency Vibration on Periodontal Tooth Mobility
Status: COMPLETED
Conditions: Tooth Mobility
Interventions: DEVICE: PTech Device|DEVICE: PTech Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Touch on Brain Connectivity and Metabolic Biomarkers in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Preterm|Infant ALL|Premature|Disease
Interventions: OTHER: osteopathic manipulative treatment|OTHER: Active comparator|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Famitinib in Patients With Advanced Non-squamous and Non-Small Cell Lung Cancer (NSCLC)
Status: SUSPENDED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Famitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: placebo|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Rivastigmine to Treat Parkinsonian Apathy Without Dementia
Status: COMPLETED
Conditions: Parkinson's Disease|Apathy|no Dementia
Interventions: DRUG: rivastigmine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders
Status: TERMINATED
Conditions: Factor VII Deficiency|Glanzmann Thrombasthenia|Hemophilia A With Inhibitor
Interventions: BIOLOGICAL: Coagulation Factor VIIa variant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Toxicity of Degarelix for Prostate Downsizing Prior to Permanent Seed Prostate Brachytherapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery
Status: SUSPENDED
Conditions: Clinical Stage II Esophageal Adenocarcinoma AJCC v8|Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Esophageal Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DRUG: Paclitaxel|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lynch Syndrome|Endometrial Neoplasms|Ovarian Neoplasms|Colorectal Neoplasms
Interventions: BEHAVIORAL: Questionnaire, Educational Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of E-EPA on Circulating LDL and Plasma Lipid Metabolism
Status: UNKNOWN
Conditions: Atherosclerosis|Low-density Lipoproteins Aggregation Susceptibility|Low-density Lipoprotein Lipid Composition|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Ethyl-Eicosapentaenoic Acid (E-EPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressure
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Beta-blocker monotherapy|DRUG: Travoprost 0.004% / timolol 0.5% fixed combination ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pendular Nystagmus in OPT
Status: COMPLETED
Conditions: Pendular Nystagmus|Oculopalatal Tremor
Interventions: DRUG: Memantine|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation in Individuals With Unilateral Transtibial Amputation
Status: UNKNOWN
Conditions: Amputation|Telerehabilitation|Exercise|Prosthesis User
Interventions: OTHER: Telerehabilitation based exercise treatment|OTHER: Home based exercise treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia
Status: UNKNOWN
Conditions: Azoospermia
Interventions: DRUG: GnRHa/ hCG/ hMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Green Tea on Treatment of Lupus
Status: COMPLETED
Conditions: Autoimmune|Lupus Erythematosus, Systemic
Interventions: DIETARY_SUPPLEMENT: green tea extract|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Safety and Efficiency of AND017 in Patients With β-thalassemia
Status: RECRUITING
Conditions: β -Thalassemia
Interventions: DRUG: AND017 capsules|DRUG: AND017 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compressive Single-piece Implants for Immediate Rehabilitation of Edentulous Maxillectomy Patients
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: OTHER: Maxillary obturator|OTHER: Implant supported obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemoglobin Maintenance in Pediatric ESRD (End-stage Renal Disease) Patients by Ferric Pyrophosphate Citrate (FPC)
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: DRUG: Triferic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usage of Multiple Drugs in Treatment of Postoperative Vomiting After Laparoscopic Appendectomy
Status: COMPLETED
Conditions: to Treat the Vomiting Frequently Occur Post-laparoscopic by Different Anti Emetic Drugs
Interventions: DRUG: Ondansetron|DRUG: isopropyl alcohol 70% inhalation|PROCEDURE: laparoscopic appendectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aligning Facility Leadership and Climate to Advance Mental Health Services Integration in Malawi
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Champion strategy|BEHAVIORAL: Adapted LOCI leadership and climate alignment strategy plus champion strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a 5-a-day Fruit and Vegetable Mobile Phone Application
Status: COMPLETED
Conditions: Nutritional Status|Nutrition Assessment
Interventions: BEHAVIORAL: 5-a-day fruit and vegetable mobile phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation|Cytomegalovirus Infections
Interventions: DRUG: sirolimus|DRUG: tacrolimus|DRUG: mycophenolate|DRUG: Prednisone|DRUG: Basiliximab|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Observational Cohort Study on the Clinical Impact of Novel Monoclonal Antibodies in B-cell Non-Hodgkin Lymphoma in Italian Clinical Practice
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma, B-cell
Interventions: DRUG: "novel" MAB (alone or in combination)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Investigating Tooth Movements With Conventional and Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) Supported Fixed Appliances
Status: UNKNOWN
Conditions: Tooth Movement|Orthodontics
Interventions: PROCEDURE: orthodontic treatment with customized archwires|PROCEDURE: orthodontic treatment with prefabricated archwires|PROCEDURE: orthodontic tx w/ conventional archwires+manual adjustments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anakinra (Kineret®) in Combination With Disease Modifying Anti-Rheumatic Drugs (DMARDS) in Subjects With Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Anakinra (Kineret®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effect & Safety of Clopidogrel Napadisilate With Clopidogrel Bisulfate in Coronary Artery Disease Patients
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: Clopidogrel|DRUG: aspirin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Do We Ultrasound-Guided Popliteal Approach Sciatic Nerve Block?
Status: RECRUITING
Conditions: Adult|Regional Anesthesia Morbidity|Anesthesia Injection Site
Interventions: OTHER: Subparaneural Injection (Grup S), Block|OTHER: Interneural Injection (Grup I), Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Lokomat Virtual Reality Applications on Balance and Gait in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Robot Asisted Gait Training with Lokomat (Endurance)|OTHER: Robot Asisted Gait Training with Lokomat (Attention and Motivation)|OTHER: Robot Asisted Gait Training with Lokomat (Activity Timing)|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide acetate|DRUG: Apalutamide|PROCEDURE: Radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition and Pregnancy Intervention Study
Status: COMPLETED
Conditions: Pregnancy|Obesity|Gestational Diabetes Mellitus|Adiposity|Type2 Diabetes|Cardiovascular Risk Factor|Eating Behavior|Liver Diseases|Neurodevelopmental Disorders|Cognitive Developmental Disorders
Interventions: DIETARY_SUPPLEMENT: Comparison of probiotics, fish oil and their combination to placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
Status: COMPLETED
Conditions: Pain|Pneumoperitoneum|Inflammation|Quality of Life
Interventions: PROCEDURE: Pneumoinsufflator mode and setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of the Medial Meniscus With the NUsurface(R) Meniscus Implant
Status: COMPLETED
Conditions: Meniscus; Degeneration|Osteoarthritis, Knee
Interventions: DEVICE: NUsurface Meniscus Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine the Maximum Tolerated Dose and Evaluate the Safety and Pharmacokinetics of Docetaxel-PNP, Polymeric Nanoparticle Formulation of Docetaxel, in Subjects With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: Docetaxel-PNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for Treating Hypertrophic Burn Scars in Children
Status: UNKNOWN
Conditions: Burn Scars
Interventions: PROCEDURE: Pulse-Dye Laser|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of OST-122 in Patients With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis Chronic Moderate|Ulcerative Colitis Chronic Severe
Interventions: DRUG: OST-122|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Energy Consumption and Cardiorespiratory Load During Overground Gait Training With a Wearable Exoskeleton After Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: OTHER: Ekso GT gait training with high swing assistance|OTHER: Ekso GT gait training with neutral swing assistance|OTHER: Ekso GT gait training with high swing resistance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Eculizumab Therapy for Subclinical Antibody-mediated Rejection in Kidney Transplantation
Status: WITHDRAWN
Conditions: Subclinical Acute Antibody-mediated Rejection in Kidney Transplantation
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, Stage II, Stage III Breast Cancer, or Ductal Carcinoma In Situ That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: chemotherapy|DRUG: endocrine therapy|GENETIC: DNA methylation analysis|GENETIC: protein analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities
Status: COMPLETED
Conditions: HIV Infections|Lipodystrophy|Hyperinsulinemia
Interventions: DRUG: Metformin hydrochloride|DRUG: Rosiglitazone maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Modified Intermittent Fasting in Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris|Psoriasis
Interventions: BEHAVIORAL: Modified Intermittent Fasting followed by Regular Diet|BEHAVIORAL: Regular Diet followed by Modified Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
Status: COMPLETED
Conditions: Medulloblastoma|Astrocytoma, Grade III|Glioblastoma|Anaplastic Astrocytoma|Brain Stem Neoplasms, Malignant|Oligodendroblastoma|Anaplastic Oligodendroglioma|Malignant Glioma
Interventions: DRUG: Mebendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIB Study to Compare the Efficacy and Safety of Concomitant Treatment in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Formoterol Fumarate|DRUG: Tiotropium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Apaziquone|DRUG: Placebo|PROCEDURE: TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of the QLB-3 for Patients Undergoing a Total Hip Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Hip Arthroplasty
Interventions: DRUG: Ropivacaine injection|OTHER: NACL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toxicity and Outcome of Whole Breast Hypofractionated Radiotherapy: a Single Institution Experience
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Quality of Life|Radiotherapy; Adverse Effect, Dermatitis or Eczema|Survivorship
Interventions: OTHER: Quality of life measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patients-ventilator Interaction During Sleep: Effect of Humidification System
Status: COMPLETED
Conditions: Chronic Hypercapnic Respiratory Failure
Interventions: DEVICE: heated humidification|DEVICE: heat and moisture exchanger|DEVICE: usual mechanical ventilation without humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High-Dose Interferon Alfa and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer or Melanoma
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Age, Weight and Ethnic Background on Blood Pressure
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Vascular Diseases|Hypertension
Interventions: OTHER: Brief lifestyle/medical history questionnaire|OTHER: Anthropometric measures|OTHER: Blood pressure and arterial stiffness|OTHER: Cardiac output and lung function|OTHER: Heart rate variability|OTHER: Blood sample & spot urine sample|OTHER: 24 hour ambulatory blood pressure monitor|OTHER: 24 hour urine collection|OTHER: Echocardiograph: Left ventricular mass|OTHER: Large artery structure: Carotid intima-media thickness|OTHER: Small artery structure: Minimum forearm vascular resistance|OTHER: Large artery endothelial function|OTHER: Small artery endothelial function: Forearm blood flow|OTHER: Dundee step test|OTHER: Detailed haemodynamic response to submaximal exercise|OTHER: Cardiopulmonary fitness: Maximum oxygen consumption|OTHER: Haemodynamic response to mental stress|OTHER: Small artery dilatory function: Forearm blood flow
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta
Status: UNKNOWN
Conditions: Mental Health Disorder|Substance Use Disorder|Stigmatization|Implementation Science
Interventions: BEHAVIORAL: Modified Health Policy Project (HPP) HIV-Stigma and Discrimination Reduction Training Curriculum|DEVICE: You℞ Decision prescribing platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Innovative Physical Therapy Modalities in People With a Neurological Disease: Oculomotor Therapy and Adapted Yoga
Status: NOT_YET_RECRUITING
Conditions: Nervous System Diseases|Oculomotor; Disorder|Physical Dependence|Physical Inactivity|Treatment Adherence
Interventions: OTHER: Oculomotor therapy|OTHER: Adapted yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Healthy People To Investigate The Safety, Toleration And Time Course Of Blood Concentrations Of Multiple Doses Of PF-03654764, Given By Mouth
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-03654764|DRUG: placebo|DRUG: PF-03654764|DRUG: placebo|DRUG: PF-03654764|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized AmnioFix Study During Radical Prostatectomy
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Robotic Assisted Laparoscopic Radical Prostatectomy (RARP)|BIOLOGICAL: AmnioFix®|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Changes With Diet.
Status: RECRUITING
Conditions: Fasting, Intermittent|Fasting Hypoglycemia|Fasting|Obesity|Diabetes
Interventions: DIAGNOSTIC_TEST: Retinal electrophysiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DOAC in Patients With Child A or B Liver Cirrhosis
Status: RECRUITING
Conditions: Liver Cirrhosis
Interventions: DRUG: Apixaban 5 MG [Eliquis]|DRUG: Edoxaban 60 MG [Lixiana]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER