pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Study for the Prognostic and Predictive Role of Circulating Tumor Cells in Patients With Oropharyngeal Squamous Cell Carcinoma: CTCO (Circulating Tumor Cells in the Oropharynx)
Status: RECRUITING
Conditions: Circulating Tumor Cell|Oropharyngeal Cancer
Interventions: BIOLOGICAL: CTC detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paradoxical Stimulation of Hepatic Glucose Production With Dapagliflozin
Status: COMPLETED
Conditions: Type II; Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation for Young Infants With Clinical Severe Infection in Tanzania
Status: NOT_YET_RECRUITING
Conditions: Neonatal Infection
Interventions: DIETARY_SUPPLEMENT: Zinc Supplements|DIETARY_SUPPLEMENT: Placebo Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Abrocitinib 200 MG Oral Tablet|DRUG: Ritlecitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Ultrasound Measurement of the Dural Sac Volume on the Sensory Level in Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: OTHER: Geometrical calculation of dural sac volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Trial of BMS-690514 in Non-Small Cell Lung Cancer Subjects Who Have Been Treated With Gefitinib or Erlotinib and Are Genotypically EGFR Mutation Positive or Who Have Had a Prior Response
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: BMS-690514
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clonidine for Infra-orbital Nerve Block During Pediatric Cleft Lip Revision Surgeries
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sacral Erector Spinae Plane Block Versus Caudal Block in Penile Surgeries in Pediatrics
Status: COMPLETED
Conditions: Sacral Erector Spinae Plane Block|Caudal Block|Penile Surgeries|Pediatrics
Interventions: PROCEDURE: Caudal block|PROCEDURE: Sacral erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pars Plana Vitrectomy for Diabetic Fibrovascular Proliferation With and Without Internal Limiting Membrane Peeling
Status: UNKNOWN
Conditions: Patients With Proliferative Diabetic Retinopathy Who Have Active Fibrovascular Proliferation
Interventions: PROCEDURE: ILM peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of M207 With Intranasal Zolmitriptan in Healthy Volunteers
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: A: M207 3.8mg, 30 min, upper arm|DRUG: B: M207 3.8 mg, 30 min, thigh|DRUG: C: M207 3.8 mg, 1 hr, upper arm|DRUG: D:zolmitriptan nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Experiences of Multiple Sclerosis (PExMS)
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Patient Engagement|Self Efficacy
Interventions: BEHAVIORAL: PExMS and DECIMS-Wiki|BEHAVIORAL: DECIMS-Wiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Phototherapy Associated to Exercise-based Rehabilitation Program in Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Physical Activity
Interventions: OTHER: Exercise|OTHER: Placebo Phototherapy|OTHER: Active Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD5672|DRUG: Etanercept|DRUG: Placebo|DRUG: AZD5672|DRUG: AZD5672|DRUG: AZD5672
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of the Oral Contraceptive (OC) Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women.
Status: COMPLETED
Conditions: Pharmacokinetics|Therapeutic Equivalency|Contraceptives, Oral
Interventions: DRUG: Norgestimate; Ethinyl Estradiol; Folic acid.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Safety of Two Ibuprofen Combination Products for the Treatment of the Common Cold and Flu in Latin America
Status: WITHDRAWN
Conditions: Common Cold
Interventions: DRUG: Advil Congestion Relief|DRUG: Advil Allergy and Congestion Relief|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Health Promoting Effects of the Microalgae Phaeodactylum Tricornutum"
Status: COMPLETED
Conditions: Human Nutrition, Omega-3 Fatty Acids, Microalgae|Micronutrients
Interventions: DIETARY_SUPPLEMENT: Microalgae|DIETARY_SUPPLEMENT: Omega-3-fatty acid capsule|DIETARY_SUPPLEMENT: sea fish
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Umbilical Cord Blood Infusion to Treat Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Autologous Umbilical Cord Blood Transfusion|BIOLOGICAL: Cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ulinastatin on Coagulation in High Risk Patients Undergoing Off Pump Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Occlusive Disease
Interventions: DRUG: ulinastatin, saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma
Status: ACTIVE_NOT_RECRUITING
Conditions: Morton's Neuroma|Pain Management
Interventions: DEVICE: Cryoanalgesia (iovera°®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GSK1358820 in Subjects With Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: GSK1358820|DRUG: Placebo|DRUG: Antibiotic therapy|OTHER: Bladder diary|OTHER: King's Health Questionnaire (KHQ)|OTHER: Overactive Bladder Symptom Score (OABSS)|OTHER: Treatment Benefit Scale (TBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients
Status: RECRUITING
Conditions: Parkinson Disease|Osteopathy in Diseases Classified Elsewhere
Interventions: PROCEDURE: Sham- Light touch, not reaching restrictive barrier|PROCEDURE: Experimental: Interventional Group- OMM- Muscle energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Chewing Gum and Gynecological Laparoscopic Surgery
Status: COMPLETED
Conditions: Gynecologic Disease|Postoperative Ileus|Paralytic Ileus
Interventions: OTHER: chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Incidence of Duodenal Stump Fistula After Gastrectomy for Gastric Cancer. A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Gastric Cancer|Duodenal Stump Leak
Interventions: DEVICE: TST-TriStaple(3lines stapler)Technology|OTHER: other conventional techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Buproprion for Binge Drinking
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: DRUG: Bupropion|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Microcirculatory Effects of Bevacizumab in Patients Treated for Metastatic Colon Cancer or Glioblastoma
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Glioblastoma|Bevacizumab|Capillaroscopy
Interventions: OTHER: capillaroscopy|OTHER: blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Immersive Virtual Reality to Train the Multisensory Processing Capacities of Children Aged 8 to 16 Years-old With an Autism Spectrum Disorder: Single-center Randomized Pilot Study in Parallel Groups - SEVIRE. (Sensory Virtual Reality)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: virtual reality training|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Corneal Collagen Crosslinking With Riboflavin for Keratoconus Treatment: A Brazilian Study
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: Corneal Collagen Crosslinking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Management Intervention For South Asians
Status: ACTIVE_NOT_RECRUITING
Conditions: HbA1c|Diabetes
Interventions: BEHAVIORAL: Community Health Worker (CHW)-led health|BEHAVIORAL: HIT-enabled|BEHAVIORAL: Physician enabled care coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3DV+TPS Applied to Radiotherapy for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharynx Cancer|Radiotherapy
Interventions: DEVICE: 3DV+TPS/VARIAN|DEVICE: TPS / VARIAN|DEVICE: 3DV + TPS / Domestic Accelerator|DEVICE: TPS / Domestic Accelerator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery
Status: COMPLETED
Conditions: Postoperative Delirium|Postoperative Cognitive Dysfunction
Interventions: DRUG: Methylene Blue|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Alcoholism|Cocaine-Related Disorders
Interventions: DRUG: Naltrexone|DRUG: Disulfiram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics After Single Rising Oral Doses of BIBR 1048 MS as Capsules in Healthy Subjects of Japanese and Caucasian Origin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS|DRUG: Placebo of BIBR 1048 MS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Humidified High Flow Nasal Cannula Versus Nasal Intermittent Positive Ventilation in Neonates
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: NIPPV|DEVICE: HHFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin B6 Effects for Women Taking Birth Control Pills
Status: COMPLETED
Conditions: Vitamin B6 Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin B6|PROCEDURE: Infusion of labeled serine, methionine and leucine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
Status: COMPLETED
Conditions: Depression|Anxiety|PTSD|Trauma, Psychological
Interventions: BEHAVIORAL: Mindfulness based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia|Pulmonary Hypertension
Interventions: DRUG: Sildenafil Oral Suspension|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Free Immunosuppression in Liver Transplantation
Status: COMPLETED
Conditions: Liver Cirrhosis|Liver Transplant Disorder
Interventions: DRUG: Steroids|DRUG: Basiliximab|DRUG: Tacrolimus|DRUG: Enteric-coated Mycophenolic acid (EC-MPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Contact Lenses With UV/HEV-Filter on Visual Function
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE OASYS 1-Day|DEVICE: ACUVUE OASYS MAX 1-Day|DEVICE: ACUVUE OASYS Multifocal|DEVICE: ACUVUE OASYS MAX 1-Day Multifocal|DEVICE: ACUVUE OASYS 1-Day for Astigmatism|DEVICE: senofilcon A based contact lens (toric) with new UV/HEV filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD6244 vs. Capecitabine (Xeloda®) in Patients With Advanced or Metastatic Pancreatic Cancer, Who Have Failed First Line Gemcitabine Therapy
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: AZD6244|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19
Status: COMPLETED
Conditions: Covid-19|Coronavirus Disease 2019
Interventions: DRUG: Bempegaldesleukin|DRUG: Standard of Care|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Versus Platinum-Based Chemotherapy for Participants With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Advanced or Metastatic Non-Small Cell Lung Cancer (MK-3475-042/KEYNOTE-042)-China Extension Study
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: pembrolizumab|DRUG: carboplatin|DRUG: paclitaxel|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Effectiveness and Safety of YVOIRE Y-Solution 720 Injected for Jawline Contouring
Status: COMPLETED
Conditions: Jaw Volume Deficit
Interventions: DEVICE: YVOIRE Y-Solution 720
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polycaprolactone / Tricalcium Phosphate (PCL/TCP) v Titanium Orbital Implant : Randomised Trial
Status: UNKNOWN
Conditions: Fractures|Enophthalmos|Diplopia
Interventions: DEVICE: Polycaprolactone / Tri-Calcium Phosphate|DEVICE: Titanium Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)
Status: RECRUITING
Conditions: Low Grade Endometrial Stromal Sarcoma
Interventions: DRUG: Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Expressive Writing on a Sample of New Mothers
Status: COMPLETED
Conditions: Maternal Distress|Health Care Utilization
Interventions: BEHAVIORAL: Expressive Writing tecnique|BEHAVIORAL: Neutral Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anesthesic Propofol and Remifentanil Requirements in Obese Patients
Status: TERMINATED
Conditions: Anesthesia|Obesity
Interventions: PROCEDURE: bariatric coelioscopic surgical procedure|PROCEDURE: supra-umbilical coelioscopic surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Catheterisation on the Bladder Mucosa of Healthy Volunteers With a Micro Hole Zone Catheter
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Nautilus Catheter|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole
Status: WITHDRAWN
Conditions: Substance Abuse|Substance Dependence
Interventions: BEHAVIORAL: Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Non Coding RNA HOTAIR and Midkine as Biomarkers in Thyroid Cancer
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: OTHER: complete blood picture ,serum urea and creatinine,liver function test,T3,T4,thyroid stimulating hormone,thyroglobuline and thyroglobuline anti body specific test Real time polymerase chain reaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Bioequivalence and Food Effects of HRX0701 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: hrx0701 tablets、Metformin hydrochloride tablets、Retagliptin phosphate tablets|DRUG: hrx0701 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammation-mediated Coronary Plaque Vulnerability, Myocardial Viability and Ventricular Remodeling
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Heart Failure
Interventions: DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: transthoracic echocardiography|DIAGNOSTIC_TEST: Late Gadolinium-Enhancement Cardiac Magnetic Resonance|DIAGNOSTIC_TEST: Coronary Angio Computed Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole (Abilify®) IM Depot Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy on Phase III Study on 300 IR SLIT to Patients Suffering From Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Primary Disease
Interventions: DRUG: 300 IR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Samaki Salama: Small-scale Fisheries for Healthy Nutrition and Ecosystems
Status: UNKNOWN
Conditions: Malnutrition, Child|Growth; Stunting, Nutritional
Interventions: BEHAVIORAL: Social marketing|BEHAVIORAL: social marketing + gear modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Risk and Chronic Inflammatory Rheumatism
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatology|Cardiovascular Diseases|Arthritis, Rheumatoid|Spondyloarthritis
Interventions: PROCEDURE: Examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assess the Long Term Efficacy and Safety of Ruxolitinib Cream in Participants With Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: ruxolitinib|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Aneurysm Aortic|Vascular Diseases
Interventions: PROCEDURE: Fenestrated and branched endovascular aortic repair (F-BEVAR)|PROCEDURE: Open repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A mHealth Intervention to Improve Symptom Control in Children and Adolescents With Difficult-to-control Asthma
Status: UNKNOWN
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Happyair Ecosystem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of First TIME Immunotolerance Induction in Severe Hemophilia A Patients With Inhibitor at High Risk of Failure: Comparison With FVIII Concentrates With or Without Von Willebrand Factor - RES.I.S.T. Naive
Status: WITHDRAWN
Conditions: Severe Hemophilia A
Interventions: DRUG: FVIII Concentrates|DRUG: FVIII/VWF concentrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Substudy 06C: A Study of Sacituzumab Tirumotecan (MK-2870) With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
Status: RECRUITING
Conditions: Gastroesophageal Junction|Gastroesophageal Adenocarcinoma|Esophageal Neoplasms|Esophageal Cancer
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Sacituzumab Tirumotecan|DRUG: Capecitabine|DRUG: Leucovorin|DRUG: Levoleucovorin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy
Status: TERMINATED
Conditions: Thrombotic Microangiopathy|Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: ARC 1779 Placebo|DRUG: ARC1779 Injection|DRUG: ARC1779 Injection|DRUG: ARC1779 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Anterior Lamellar Keratoplasty Using Dehydrated Versus Standard Organ Culture Stored Donor Corneas
Status: UNKNOWN
Conditions: Keratoconus
Interventions: PROCEDURE: Deep anterior lamellar keratoplasty|PROCEDURE: Deep anterior lamellar keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Levetiracetam in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Epilepsy
Interventions: DRUG: Levetiracetam|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized 1µg Adrenocorticotropic Hormone Stimulation Test, and Salivary Cortisol Concentration During the Test
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: ACTH stimulation test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Spinal Anesthesia - Intraocular Pressure
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: OTHER: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation.
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Encorafenib and Binimetinib|DRUG: Placebo to match Encorafenib ; Placebo to match Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Obesity Effect of Pediococcus Pentosaceus LP28
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Live Pediococcus pentosaceus LP28|DIETARY_SUPPLEMENT: Heat-killed Pediococcus pentosaceus LP28|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Status: RECRUITING
Conditions: Type2diabetes|Heart Failure|Obesity
Interventions: BEHAVIORAL: Community Champions|BEHAVIORAL: Homegrown Heroes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sunitinib in Treating Patients With Advanced Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Recurrent Malignant Mesothelioma
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Kidney and The Brain Study - Assessment of Cognitive Impairment in Advanced CKD
Status: COMPLETED
Conditions: Cognitive Impairment|Chronic Kidney Diseases|End Stage Renal Disease|Dementia|Hemodialysis Complication|Peritoneal Dialysis Complication|Renal Transplant
Interventions: PROCEDURE: Cognitive Assessment|DIAGNOSTIC_TEST: Depression and Quality of Life Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhanced Recovery After Surgery for SPK Transplantation Recipients
Status: COMPLETED
Conditions: Transplant Complication|Diabetic Nephropathy|Perioperative/Postoperative Complications
Interventions: PROCEDURE: Enhanced recovery for SPK recipients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Undifferentiated Carcinoma|Gastric Adenocarcinoma|Gastric Squamous Cell Carcinoma|Recurrent Esophageal Adenocarcinoma|Recurrent Esophageal Squamous Cell Carcinoma|Recurrent Gastric Carcinoma|Stage IIIB Esophageal Adenocarcinoma|Stage IIIB Esophageal Squamous Cell Carcinoma|Stage IIIB Gastric Cancer|Stage IIIC Esophageal Adenocarcinoma|Stage IIIC Esophageal Squamous Cell Carcinoma|Stage IIIC Gastric Cancer|Stage IV Esophageal Adenocarcinoma|Stage IV Esophageal Squamous Cell Carcinoma|Stage IV Gastric Cancer|Undifferentiated Gastric Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Oxaliplatin|DRUG: Pralatrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT)
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Etelcalcetide|DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of GSK573719 (LAMA) and GW642444 (LABA)Administered Individually and Concurrently in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of a Novel Small Molecule EBNA1 Inhibitor, VK 2019, in Patients With Epstein Barr Virus (EBV)-Positive Nasopharyngeal Cancer (NPC) and Other Epstein-Barr Virus (EBV)-Associated Cancers, With Pharmacokinetic and Pharmacodynamic Correlative Studies
Status: RECRUITING
Conditions: Nasopharyngeal Cancer|Epstein-Barr Virus Related Carcinoma
Interventions: DRUG: VK-2019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Mid-morning Breakfast as Healthy as Early-morning Breakfast for Blood Sugar Control in Adolescent Girls?
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: OTHER: breakfast omission (BO)|OTHER: early-morning breakfast consumption (EM-BC)|OTHER: mid-morning breakfast consumption (MM-BC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravaginal Prasterone (DHEA) Against Vulvovaginal Atrophy Associated With Menopause
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Placebo|DRUG: Prasterone (DHEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study Assessing Efficacy of a Cisplatin - Métronomic Cyclophosphamide Treatment in Patients With Stade IV Triple Negative Breast Cancer Secondary Resistant to Anthracyclines and Taxanes
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Cisplatin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hema-NeoTIL01 Cell Infusion Therapy in Relapsed/Refractory Acute Leukemia
Status: NOT_YET_RECRUITING
Conditions: Leukemia, Myeloid, Acute|B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Hema-NeoTIL01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001)
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Mantle-cell Lymphoma|Primary Mediastinal B-cell Lymphoma
Interventions: BIOLOGICAL: JCAR017 (lisocabtagene maraleucel) single-dose schedule|BIOLOGICAL: JCAR017 (lisocabtagene maraleucel) 2-dose schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Information Technology System ("Roadmap 2.0") in the Context of Hematopoietic Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematologic Diseases
Interventions: OTHER: Wearable activity sensor|BEHAVIORAL: Roadmap 2.0 information system|OTHER: Survey administration|BEHAVIORAL: Roadmap 2.0 information system with Positive Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Goal-directed Algorithms of Hemodynamic Therapy After Combined Valve Repair
Status: COMPLETED
Conditions: Valvular Heart Disease
Interventions: DEVICE: Swan-Ganz catheter|DEVICE: transpulmonary thermodilution + central venous saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Nutritional Choices in Adolescents
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Full LIITA3H App|OTHER: Partial LIITA3H App|OTHER: LIITA3H Location only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Technology and Assessing the Biological Effects of Commercially Available PhotoBioModulation Devices
Status: RECRUITING
Conditions: Physiological Wellness
Interventions: DEVICE: NovoTHOR XL Photobiomodulation Full Body Light Bed|DEVICE: ARRC LED Photobiomodulation Full Body Light Bed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RCT Versus Placebo of rTMSQP Over Visual Cortex for the Prevention of Chronic Migraine
Status: WITHDRAWN
Conditions: Chronic Migraine
Interventions: DEVICE: Super Rapid Magstim Stimulator|DEVICE: Super Rapid Magstim Stimulator (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: MOA-728|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy or Conservative Treatment in the Acute Cholecystitis of Elderly Patients
Status: UNKNOWN
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Laparoscopic cholecystectomy|PROCEDURE: Non-operative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled NO in Surgical Patients With Recent COVID-19 Infection
Status: COMPLETED
Conditions: Nitric Oxide|COVID-19|Surgery|Postoperative Complications
Interventions: DRUG: Nitric Oxide Gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cleansing Device for the Treatment of Scalp and Hair Conditions
Status: RECRUITING
Conditions: Dandruff|Seborrheic Dermatitis|Hair Loss
Interventions: DEVICE: Off-brand Waterpik®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: PF-06651600
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Yoga on Nurses Psychological Resilience and Sleep Quality During the Pandemic Period
Status: COMPLETED
Conditions: Laughter Yoga
Interventions: OTHER: laughter yoga for nurses|OTHER: laughter yoga for nurses-Deep breathing exercises|OTHER: laughter yoga for nurses-Warm-up exercises|OTHER: laughter yoga for nurses-Childish games|OTHER: laughter yoga for nurses-Laughter exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allogeneic Transplant in HIV Patients (BMT CTN 0903)
Status: COMPLETED
Conditions: Leukemia|Lymphoma|HIV
Interventions: DRUG: Fludarabine and Busulfan|DRUG: Fludarabine and Melphalan|DRUG: Busulfan and Fludarabine|DRUG: Cyclophosphamide and Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Cognitive Disorder
Interventions: PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Fructose Diet, the Gut Microbiome, and Metabolic Health
Status: NOT_YET_RECRUITING
Conditions: MASLD|Type 2 Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: Fructose|DIETARY_SUPPLEMENT: glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Haploidentical CD34+ Selected Cells Combined With Single Unit Umbilical Cord Blood Transplant for Treatment of High-risk Hematologic Disorders
Status: RECRUITING
Conditions: Hematologic Disorders
Interventions: DEVICE: Miltenyi CliniMACS® CD34 Reagent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WW Improving Nutrition Study: A Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: WW|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cleanser for Acute Wounds
Status: NOT_YET_RECRUITING
Conditions: Acute Wound
Interventions: DEVICE: Antimicrobial Skin & Wound Cleanser (AWC)|DEVICE: Antimicrobial Wound Gel (AWG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Vitamin D Insufficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: High Dose Vitamin D3|DIETARY_SUPPLEMENT: Low Dose Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sensory Motor Training and Kinesthetic Exercises in Knee Osteoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: sensory motor training|OTHER: kinesthetic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous 5% Dextrose Infusion During Recovery From Anesthesia on the Quality of Early Postoperative Recovery in Patients Undergoing Painless Gastrointestinal Endoscopy
Status: RECRUITING
Conditions: Insulin Resistance|Postoperative Nausea and Vomiting|Quality of Recovery
Interventions: OTHER: 5% glucose|OTHER: 0.9% Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of MSB2311 in Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: 10 mg/kg Q2W|DRUG: 20 mg/kg Q3W
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomics of GLP1 Receptor Agonists
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Exenatide Injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Access the Efficacy and Safety of Solriamfetol in Subjects With ADHD (FOCUS)
Status: RECRUITING
Conditions: ADHD
Interventions: DRUG: Solriamfetol 150 mg|DRUG: Solriamfetol 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Via Respimat® Inhaled BI 1744 CL Compared to Moxifloxacin and Placebo in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1744 CL solution for inhalation|DRUG: Placebo matching BI 1744 CL|DRUG: Moxifloxacin (Avalox®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST)
Status: RECRUITING
Conditions: Gastro Intestinal Stromal Tumor
Interventions: DRUG: oral tyrosine-kinase inhibitors (TKI) of KIT and PDGFR as per recommendations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Clinical Trial of "Botulax®" to Treat Children With Cerebral Palsy
Status: COMPLETED
Conditions: Other Infantile Cerebral Palsy
Interventions: DRUG: Botulinum Toxin Type A(Botox®)|DRUG: Botulinum toxin type A(Botulax®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Music, Sleep and Dementia Study
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Circadian Rhythm Disorders|Circadian Rhythm Sleep Disorder|Insomnia|Hypersomnia|Cognitive Impairment|Cognitive Decline|Mild Cognitive Impairment|Frontotemporal Dementia|Neurocognitive Disorders|Vascular Dementia|Sleep Disorder|Memory Impairment
Interventions: BEHAVIORAL: Tailored music listening intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rubinstein-Taybi Syndrome: Functional Imaging and Therapeutic Trial
Status: COMPLETED
Conditions: Rubinstein-Taybi Syndrome
Interventions: DRUG: sodium valproate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Heart Failure With Preserved Ejection Fraction|Heart Conduction Disorder
Interventions: DEVICE: Conduction system pacing|DEVICE: Right ventricular apical pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marginal Bone Changes of CAD/CAM Implant Supported Screw-retained and Screw-mented Metal Frameworks
Status: UNKNOWN
Conditions: Patient Satisfaction|Bone Loss
Interventions: PROCEDURE: screwmented metal frameworks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Long-term Safety, Tolerability and Efficacy of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Interventions: DRUG: Rozanolixizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the Liquid Formulation of Group B Streptococcus Trivalent Vaccine and of the Lyophilized Formulation of Group B Streptococcus Trivalent Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcal Infections
Interventions: BIOLOGICAL: GBS Vaccine|BIOLOGICAL: GBS Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Smartphone App for African American Men (FitBros) Ph II
Status: RECRUITING
Conditions: Exercise|Health Behavior|Technology
Interventions: BEHAVIORAL: FitBrothers smartphone active app|BEHAVIORAL: Nike Training Club
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Pioglitazone in Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Hepatitis
Interventions: DRUG: Pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT