pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Integrated NCD Intervention in Rural Nepal
Status: WITHDRAWN
Conditions: Noncommunicable Diseases|Hypertension|Chronic Obstructive Pulmonary Disease|Diabetes Mellitus, Type 2
Interventions: OTHER: Bundled NCD WHO PEN Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Use of Dendritic Cell/Tumor Fusions as a Novel Tumor Vaccine in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Dendritic Cell Tumor Fusion Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Oxytocin and Vasopressin on Social Behavior
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Oxytocin|DRUG: Arginine Vasopressin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anabolic Properties of Canola
Status: RECRUITING
Conditions: Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: drink ingestion|BEHAVIORAL: resistance-type exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Regimens of Vitamin D in Treatment of Children With Chronic Liver Disease
Status: COMPLETED
Conditions: Chronic Liver Disease and Cirrhosis
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of SEP-363856 in Subjects With Parkinson's Disease Psychosis
Status: COMPLETED
Conditions: Parkinson Disease Psychosis
Interventions: DRUG: SEP-363856|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Hypoglycaemia and Arrhythmias in the Patient With Diabetes and CKD - Validation Study
Status: COMPLETED
Conditions: Diabetes|Hypoglycaemia|Chronic Kidney Disease
Interventions: DEVICE: 12-lead ECG T-shirt|DEVICE: Dexcom G4-System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Cancer of Head and Neck|Triple Negative Breast Cancer|Epithelial Ovarian Cancer|Malignant Melanoma|Advanced Solid Tumors
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality on Perioperative Anxiety, Stress and Pain in Total Hip Arthroplasty
Status: RECRUITING
Conditions: Virtual Reality|Total Hip Arthroplasty|Anxiety|Stress|Pain
Interventions: OTHER: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Anti-Interleukin 6-receptor (IL6R) Nanobody in Rheumatoid Arthritis (RA) Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: ALX-0061|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of N-acetyl Cysteine During Percutaneous Coronary Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: N-acetyl cysteine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Study on Lactibiane Topic AD on Skin Flora and Barrier Reinforcement in Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Lactibiane Topic AD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vibrant Capsule vs. Placebo for Patient Suffering From Constipation
Status: COMPLETED
Conditions: Constipation Chronic Idiopathic
Interventions: DEVICE: Vibrant capsule|DEVICE: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics
Status: COMPLETED
Conditions: Methemoglobinemia
Interventions: DRUG: 4% prilocaine plain|DRUG: 2% Lidocaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: 68Ga-PSMA-11 Patients With Newly Diagnosed and Recurrent Prostate Cancer (Firefly)
Status: NO_LONGER_AVAILABLE
Conditions: Prostatic Neoplasms|Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: 68 Ga-PSMA-11 prepared using a PSMA-11 Sterile Cold Kit
Study Type: EXPANDED_ACCESS
Clinical trial: Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions
Status: UNKNOWN
Conditions: Intrauterine Adhesion|Scar
Interventions: PROCEDURE: Scar tissue is removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4929097 in Patients With Advanced Renal Cell Carcinoma That Have Failed Vascular Endothelial Growth Factor (VEGF)/Vascular Endothelial Growth Factor Receptor (VEGFR) Therapy
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: DRUG: Gamma-Secretase Inhibitor RO4929097|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VentaProst in Subjects With COVID-19 Requiring Mechanical Ventilation
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: VentaProst (inhaled epoprostenol delivered via a dedicated delivery system)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: Placebo|DRUG: Brivaracetam 2.5 mg|DRUG: Brivaracetam 10 mg|DRUG: Brivaracetam 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Daily Intake of SATIOSTAT Over 6 Weeks on Weight Loss, Glucose Tolerance, Gastrointestinal Tolerance and Gut Microbiota.
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: SATIOSTAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Exercise and Counseling Intervention on Relapse in Smoker With Depressive Disorders
Status: TERMINATED
Conditions: Smoking Cessation|Depression
Interventions: BEHAVIORAL: Exercise and counseling (for smoking cessation and physical activity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
Status: RECRUITING
Conditions: Gastric Cancer|Gastric Neoplasm|Gastrointestinal Stromal Sarcoma|Gastrointestinal Stromal Neoplasm|Gastrointestinal Stromal Tumor (GIST)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.
Status: COMPLETED
Conditions: Hepatitis C|HCV|Tuberculosis|Rifampin|Pharmacokinetics
Interventions: DRUG: TMC435350|DRUG: Rifampin|DRUG: TMC435350+rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile, Semi-automated Text Message-based Intervention to Prevent Perceived Low or Insufficient Milk Supply
Status: COMPLETED
Conditions: Breast Feeding
Interventions: BEHAVIORAL: MILK or Text4Baby text message intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Ranging Study In Subjects With Type 2 Diabetes Mellitus Who Are Treatment-Naive
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZithromycin Against pLacebo in Exacerbations of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Zithromax|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ASYMMETRIC LACK OF KNEE FLEXION AS A SYMPTOM OF DLM IN CHILDREN
Status: COMPLETED
Conditions: Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM
Interventions: DIAGNOSTIC_TEST: Find a link between lack of knee flexion and meniscal posterior luxation fixed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot-Study for SAS Treatment in Acute Cerebral InfarctiOn: the PISTACIO Trial
Status: UNKNOWN
Conditions: Ischemic Stroke|Sleep Apnea Syndromes
Interventions: DEVICE: Nocturnal Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Very High Risk Prostate Carcinoma
Interventions: RADIATION: [177Lu]Lu-PSMA-617|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-06263507 In Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Carcinoma, Non Small Cell Lung|Breast Neoplasms|Ovarian Neoplasms
Interventions: DRUG: PF-06263507|DRUG: PF-06263507
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen to Prevent Ischemic Oxidative Reperfusion Injury During Percutaneous Coronary Intervention for Acute Myocardial Infarction
Status: WITHDRAWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Amoxicillin and Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of a New GSK Biologicals' GSK2231395A Candidate Vaccine
Status: TERMINATED
Conditions: Haemophilus Influenzae|Streptococcus Pneumoniae
Interventions: BIOLOGICAL: GSK2231395A|BIOLOGICAL: TwinrixTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: XNW4107
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HOME: Home Monitoring of High-risk Pregnancies
Status: ENROLLING_BY_INVITATION
Conditions: Hypertensive Disorder of Pregnancy|Premature Preterm Rupture of Membranes|Preeclampsia|High Risk Pregnancy|Previous Adverse Obstetric Outcome
Interventions: OTHER: Home surveillance of pregnancies at risk
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Continuous Low Doses of Vinorelbine, Cyclophosphamide and Interferon Alpha 2b (" Metronomic Chemotherapy ") for Antiangiogenic and Antivascular Effect. Trial With Pharmacodynamic Study in Adult Advanced Neoplasm
Status: COMPLETED
Conditions: Advanced Neoplasm
Interventions: DRUG: Vinorelbine, Cyclophosphamide and Interferon alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Blood Pressure Measurement With an Omron HEM-907 Device in a Clinical Setting and a Research Setting
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Sequence: Clinical/Research|OTHER: Sequence: Research/Clinical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Technology Development for Physical Rehabilitation of Patients With Upper Extremity Motor Deficits (RePlay)
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Physical exam and medical history|DIAGNOSTIC_TEST: Assessments|DEVICE: Patient Instruction and use of Device (RePlay)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB086550
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: INCB086550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc
Status: COMPLETED
Conditions: Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and Metformin
Interventions: DRUG: Onglyza (saxagliptin)|DRUG: Diabex|DRUG: 5-mg saxagliptin/1000 mg metformin|DRUG: Diabex|DRUG: 5-mg saxagliptin/500 mg metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial
Status: COMPLETED
Conditions: Left Sided Heart Failure|Left Ventricular Assist Device|Anticoagulant Therapy|Gastro Intestinal Bleeding|Thrombosis, LVAD|Anti-factor Xa|aPTT|Heparin
Interventions: DEVICE: aPTT guided heparin management|DEVICE: Anti-factor Xa guided heparin management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Exergames on an Unstable Surface in Stroke Inpatients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: exergame-based cognitive-motor training on an unstable surface|OTHER: exergame-based cognitive-motor training on an stable surface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time Identification of the Aberrant Left Hepatic Arterial Territory in the Liver Using Near-infrared Fluorescence Imaging
Status: COMPLETED
Conditions: Stomach Neoplasm
Interventions: PROCEDURE: Group1|PROCEDURE: Group2|PROCEDURE: Group3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mhealth and Teach-Back Effectiveness In 30-Day Readmissions Reduction
Status: UNKNOWN
Conditions: Readmission|mHealth|Teach-Back Communication
Interventions: OTHER: mHealth|BEHAVIORAL: Teach-back
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Adding Auditory Information on Head Movements in People With Non-traumatic Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Healthy|Neck Pain
Interventions: DEVICE: Smartphone playing a sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Deferiprone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: CBD/PEA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ethanol Lock Solution in Prevention of Catheter Related Bloodstream Infection for Patients Suffering Acute Renal Failure, and Hospitalized in Intensive Care Unit. A Multi-Center, Randomized, Versus Placebo, Double Blinded Clinical Trial
Status: COMPLETED
Conditions: Acute Renal Failure|Infection
Interventions: OTHER: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Influence of Amlodipine on the Mortality of Patients With End-Stage Renal Failure
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dronabinol on the Acquisition and Consolidation of Trauma-Associated Memories
Status: RECRUITING
Conditions: Intrusive Memories
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Tiotropium and Atrovent in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium inhalation powder capsule|DRUG: Placebo Metered Dose Inhaler|DRUG: Ipratropium Bromide Metered Dose Inhaler|DRUG: Placebo inhalation powder capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Psychosocial Dyadic Programme for Patients With Heart Failure and Their Family Caregivers
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: 12-week psychosocial dyadic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Augmented Berlin-Frankfurt-Munster Therapy Plus Ofatumumab for Young Adults With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Status: TERMINATED
Conditions: Leukemia|Precursor-B Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma|Lymphoma
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: PEG asparaginase|DRUG: Ofatumumab|DRUG: Rituximab|DRUG: Methotrexate|DRUG: Cyclophosphamide|DRUG: Mercaptopurine|DRUG: Doxorubicin|DRUG: Dexamethasone acetate|DRUG: Thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Fentanyl in General Anesthesia for Craniotomy With or Without 0.5% Levobupivacaine Scalp Block
Status: COMPLETED
Conditions: Brain Tumor
Interventions: DRUG: Levobupivacaine|OTHER: NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Variation of Impedance Cardiography(DYVIC) as a Diagnostic Tool of Acute Heart Failure (AHF)
Status: COMPLETED
Conditions: Acute Heart Failure
Interventions: OTHER: Reference position|OTHER: sitting position|OTHER: Valsalva maneuver|OTHER: a passive leg rising maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pulse Endovascular ReperFUSION for Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke AIS|Cerebral Arterial Disease
Interventions: DEVICE: Pulse NanoMED System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Broncho-Vaxom in the First Episode of Pediatric Idiopathic Nephrotic Syndrome
Status: UNKNOWN
Conditions: Nephrotic Syndrome in Children
Interventions: DRUG: Broncho-Vaxom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula vs NPPV in Moderate Chronic Obstructive Pulmonary Disease Exacerbation
Status: UNKNOWN
Conditions: COPD Exacerbation
Interventions: DEVICE: High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Appendicitis
Status: COMPLETED
Conditions: Appendicitis|Appendicitis Acute|Retrocecal Appendicitis
Interventions: PROCEDURE: Appendectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Almonertinib With Bevacizumab for EGFR-Mutant NSCLC Patients With Leptomeningeal Metastasis
Status: NOT_YET_RECRUITING
Conditions: NSCLC|Leptomeningeal Metastasis|EGFR Activating Mutation
Interventions: DRUG: Almonertinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
Status: COMPLETED
Conditions: Adult Acute Lymphocytic Leukemia
Interventions: DRUG: Asparaginase|DRUG: Vincristine|DRUG: Daunorubicin, Adriamycin|DRUG: Cyclophosphamide|DRUG: Ifosfamide|DRUG: Cytarabine|DRUG: Mitoxantrone|DRUG: Methotrexate|DRUG: 6-Mercaptopurine|DRUG: 6-Thioguanine|DRUG: VM26|DRUG: Dexamethasone / Prednisolone|PROCEDURE: CNS Irradiation|PROCEDURE: Mediastinal Irradiation|PROCEDURE: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thermograph Evaluation of Masticatory and Cervical Muscles After Physiotherapeutic Treatment in Tmd Subjects
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction
Interventions: OTHER: Manual Therapy Treatment|DEVICE: Placebo Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micafungin Prevention Study for Invasive Fungal Disease in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Neutropenia|Fungal Disease
Interventions: DRUG: micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Neoplasms|Rectal Cancer
Interventions: RADIATION: Radiotherapy|DRUG: Capecitabine|DRUG: Fluorouracil|DRUG: Atezolizumab|DRUG: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at the Efficacy and Safety of Keppra® Extended Release Formulation - XR
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Keppra® extended release formulation - XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: BCG instillation therapy|DRUG: Sequential BCG and EMDA mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of OCS-01 Eye Drops in Subjects Following Cataract Surgery
Status: RECRUITING
Conditions: Inflammation Eye|Pain, Postoperative|Cataract
Interventions: DRUG: Dexamethasone Ophthalmic Suspension|OTHER: Vehicle of OCS-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Febuxostat on Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas
Status: COMPLETED
Conditions: Lymphomas|Solid Tumors|NSCLC|Metastatic Colon Carcinoma|Granulosa Cell Ovarian Cancer
Interventions: DRUG: TRC102|DIAGNOSTIC_TEST: CT scan|OTHER: Lomotil|OTHER: Prochlorperazine|OTHER: Metoclopramide|OTHER: 5-HT3 antagonist|OTHER: Aprepitant|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Internet Based Education and Support Program for Patients Awaiting Kidney Transplantation
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: BEHAVIORAL: Internet based education and support program for patients awaiting kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Short-term Safety and Use Patterns of an Electronic Nicotine Delivery System
Status: UNKNOWN
Conditions: Nicotine Dependence
Interventions: OTHER: NJOY King 26 mg nicotine Electronic Nicotine Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of MMFS Dosages in Older Adults
Status: COMPLETED
Conditions: Anxiety|Depression|Sleep Quality|Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Low Dose MMFS-205-SR|DIETARY_SUPPLEMENT: High Dose MMFS-205-SR|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of IMCY-0098 in Patients With Recent Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: IMCY-0098|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Placebo|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: First-in-man Trial Evaluating the Safety and Efficacy of the NOVA Intracranial Stent (NOVA Trial)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: NOVA Intracranial Sirolimus Eluting Stent System|DEVICE: Apollo Intracranial Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bispecific T-cell Redirectors as Part of First Line Treatment in Transplant Eligible Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Talquetamab|DRUG: Teclistamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Vaccine in Healthy Infants in Taiwan (V441-001)(COMPLETED)
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Poliomyelitis
Interventions: BIOLOGICAL: V441, diptheria, tetanus, acellular pertussis, inactivated poliomyelitis, hepatitis B (recombinant), & Haemophilus influenza type b conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics of DWJ1439, DWJ1464, DWC202003 or DWC202004 in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: DWJ1439|DRUG: DWJ1464|DRUG: DWC202003|DRUG: DWC202004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea|Irritable Bowel Syndrome Mixed
Interventions: OTHER: Faecal microbiota transplantation with active study microbiota first|OTHER: Faecal microbiota transplantation with inactive autoclaved study microbiota first|OTHER: Faecal microbiota transplantation with inactive autoclaved study microbiota only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephrolithiasis
Status: UNKNOWN
Conditions: Secondary Hyperoxaluria|Nephrolithiasis
Interventions: DRUG: Lanthanum Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs On-demand Therapy With Kogenate Bayer in Patients With Severe Haemophilia A."
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Recombinant Factor VIII (Kogenate FS, BAY14-2222)|DRUG: Recombinant Factor VIII (Kogenate FS, BAY14-2222)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Hepatic Encephalopathy With Flumazenil and Change in Cortical GABA Levels in MRS
Status: WITHDRAWN
Conditions: Hepatic Encephalopathy|Liver Cirrhosis
Interventions: DRUG: Flumazenil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Progesterone on Stress Reactivity and Cannabis Use
Status: COMPLETED
Conditions: Cannabis Use
Interventions: DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy
Status: UNKNOWN
Conditions: Osteoarthritis|Traumatic Arthritis
Interventions: DEVICE: Chondron Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pre-medical Consultation Diabetes Self-care Education Programme on Glycemic Control in Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Pre-medical consultation structured diabetes self-care education programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome
Status: COMPLETED
Conditions: Bone Marrow Edema
Interventions: DRUG: Aclasta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Randomized, Placebo-Controlled Trial of MLN1202 on C-Reactive Protein Levels in Patients With Risk Factors for Cardiovascular Disease
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: MLN1202|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of Elagolix in Patients With Moderate to Severe Endometriosis-Associated Pain
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Elagolix|DRUG: Elagolix placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DaxibotulinumtoxinA for Injection for the Management of Plantar Fasciitis
Status: TERMINATED
Conditions: Plantar Fasciitis
Interventions: BIOLOGICAL: daxibotulinumtoxin type A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia
Status: COMPLETED
Conditions: Childhood Acute Lymphoblastic Leukemia|Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: VIR-2218|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cigarette Cravings in Smokers
Status: UNKNOWN
Conditions: Cigarette Smoking|Addiction Nicotine|Tobacco Use
Interventions: BEHAVIORAL: Stress induction|BEHAVIORAL: Control stress exposure|BEHAVIORAL: Cue induction|BEHAVIORAL: Neutral cue exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Isolated Iliac Vein Stenting Versus Concomitant Iliac Vein Stenting With Pelvic Vein Embolization in Patients With Pelvic Venous Insufficiency Secondary to Nonthrombotic Iliac Vein Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonthrombotic Iliac Vein Lesions|Pelvic Congestive Syndrome
Interventions: PROCEDURE: iliac vein stenting|PROCEDURE: pelvic vein embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Optimization of a Low-dose Computed Tomography Protocol in Patients With Suspected Uncomplicated Acute Appendicitis
Status: COMPLETED
Conditions: Appendicitis|Other and Unspecified Acute Appendicitis|Acute Disease|Gastrointestinal Diseases|Intra-abdominal Infection
Interventions: RADIATION: Low-dose CT|PROCEDURE: Laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity
Status: COMPLETED
Conditions: Pregnant Patients With Obesity
Interventions: DRUG: High-dose oxytocin|DRUG: Low-dose oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the Non-FDA Approved Product for the Correction of Nasolabial Folds (NLFs)
Status: COMPLETED
Conditions: Facial Wrinkles
Interventions: DEVICE: NADGL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of Maintenance Therapy in Patients With Incurable Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Incurable Colorectal Cancer|RAS-wild-type
Interventions: DRUG: Cetuximab|DRUG: irinotecan|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperimmune Colostrum and Oral Mucositis
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: hyperimmune colostrum|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Alendronate With Atorvastatin in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: SRP and Placebo gel|DRUG: SRP and Atorvastatin|DRUG: SRP and Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin and the Preservation of Beta-cell Function in Women With Recent Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of DE-110 Ophthalmic Suspension for the Treatment of Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: DE-110 ophthalmic suspension high dose|DRUG: DE-110 ophthalmic suspension low dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Response of Desloratadine Syrup in the Relief of Symptoms Associated With Perennial Allergic Rhinitis in Pediatric Patients (Study P04299)
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: Desloratadine (assigned by investigator as part of normal practice)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Recurrent Glioblastoma (GB)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: LY2157299 monohydrate|DRUG: Lomustine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion
Status: COMPLETED
Conditions: Cutaneous Lupus Erythematosus-Systemic Lupus Erythematosus
Interventions: DRUG: hydroxychloroquine (Z0188)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of PEX168 in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PEX168(100µg)|DRUG: PEX168(200µg)|DRUG: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (RMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Fenebrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupressure and Relaxation for Nausea Control
Status: COMPLETED
Conditions: Nausea
Interventions: BEHAVIORAL: Acupressure expectancy enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Presence of Piriformis Syndrome in Patients With Lumbar Disc Bulging and Protrusion
Status: COMPLETED
Conditions: Piriformis Syndrome
Interventions: DIAGNOSTIC_TEST: Lasegue's, Freiberg's and, FAIR (Flexion Adduction Internal Rotation) tests.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia
Status: UNKNOWN
Conditions: Sickle Cell Anemia|Beta-Thalassemia|Microalbuminuria
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Asthma Attacks in Disadvantaged School Children With Asthma
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: BACK-S|BEHAVIORAL: BACK-E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Molecular-targeted Therapy Using Zinc Finger Nuclease in Cervical Precancerous Lesions
Status: UNKNOWN
Conditions: Human Papillomavirus-Related Malignant Neoplasm
Interventions: BIOLOGICAL: ZFN-603 and ZFN-758
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With Tasquinimod Treating Patients With Hepatocellular, Ovarian, Renal Cell and Gastric Cancers
Status: COMPLETED
Conditions: Advanced or Metastatic Hepatocellular Cancer|Advanced or Metastatic Ovarian Cancer|Metastatic Renal Cell Cancer|Advanced or Metastatic Gastric Carcinoma
Interventions: DRUG: Tasquinimod|DRUG: Tasquinimod|DRUG: Tasquinimod|DRUG: Tasquinimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Papillary Epinephrine Spraying on Post-ERCP Pancreatitis in Patients Received Rectal Indomethacin
Status: TERMINATED
Conditions: Pancreatitis|Endoscopic Retrograde Cholangiopancreatography
Interventions: DRUG: Papillary epinephrine spraying|DRUG: Papillary saline spraying|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: busulfan, melphalan and fludarabine|DRUG: busulfan, melphalan and fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occupational/Physical Therapy to Reduce Morbidity Post-Operative Bilateral Breast Reconstruction
Status: WITHDRAWN
Conditions: Occupational/Physical Therapy|Post-operative Breast Reconstruction
Interventions: OTHER: Home therapy|OTHER: Structured In-Office Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care
Status: COMPLETED
Conditions: Epidermolysis Bullosa Dystrophica|Epidermolysis Bullosa
Interventions: DEVICE: Helicoll|DEVICE: Standard of Care Dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT