pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AV Delay Optimization vs. Intrinsic Conduction in Pacemaker Patients With Long PR Intervals
Status: COMPLETED
Conditions: Atrioventricular Block|Sick Sinus Syndrome|Symptomatic Bradycardia|Cardiac Arrhythmia
Interventions: DEVICE: Long, fixed AV delay|DEVICE: Short, optimized AV delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy
Status: COMPLETED
Conditions: Gaucher Disease, Type 1
Interventions: DRUG: Ambroxol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib Hydrochloride Capsule Combined With AK105 Injection in Subject With Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
Status: UNKNOWN
Conditions: Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
Interventions: DRUG: Anlotinib hydrochloride capsule|DRUG: AK105 injection|DRUG: Paclitaxel injection|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micropulsed Laser in Association With Anti-VEGF for the Treatment of Macular Edema in Diabetic Patients (LAMED).
Status: TERMINATED
Conditions: Macular Edema|Mellitus Diabetes
Interventions: RADIATION: Micropulsed laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Prognostic Value of T7 and T12 Slices on Mortality in Resuscitation Patients With ARDS Caused by SARS-COV2 Infection
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrom (SARS-Cov 2)
Interventions: OTHER: Data collection|OTHER: analysis of thoracic scans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ending the HIV Epidemic Through Point-of-Care Technologies (EHPOC)
Status: RECRUITING
Conditions: HIV Infections|Syphilis
Interventions: DIAGNOSTIC_TEST: Cepheid GeneXpert HIV-1 Qual POC HIV VL test|DIAGNOSTIC_TEST: DPP HIV-Syphilis test system|DIAGNOSTIC_TEST: OraQuick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Ease Spray in Reducing Needle Pain Associated With Intravenous Insertion in Children
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Pain Ease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bydureon on Carotid Atherosclerosis Progression in Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Bydureon|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Home Based Early Intervention of Extremely Premature Infant by Parent
Status: UNKNOWN
Conditions: Preterm|Extreme Prematurity|Early Intervention|Developmental Delay|Motor Outcome|Home Exercise|Parents
Interventions: OTHER: Home Based Early Intervention by Parent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Vorinostat|RADIATION: 131- I Metaiodobenzylguanidine|PROCEDURE: Peripheral Blood Stem Cell Infusion|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Follow-up Trial of Patients Previously Treated With Imlifidase Prior to Kidney Transplantation and a Non-comparative Transplanted Patient Group
Status: RECRUITING
Conditions: Long Term Efficacy and Safety
Interventions: DRUG: Imlifidase administered in the 20-HMedIdeS-19 (PAES) study|OTHER: Best available treatment administered in the 20-HMedIdeS-19 (PAES) study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects
Status: COMPLETED
Conditions: Heptic Impairment
Interventions: DRUG: Lu AE58054 encapsulated film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Anorectal Testing to Predict Outcomes With Biofeedback Therapy: Clinical Trial
Status: COMPLETED
Conditions: Constipation
Interventions: DEVICE: Rectal Expulsion Device (RED) - Feasibility|DEVICE: Rectal Expulsion Device (RED) - Validation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: OmniHeart Trial: Macronutrients and Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Atherosclerosis|Hypertension
Interventions: OTHER: CARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer
Status: UNKNOWN
Conditions: Prostatic Neoplasms, Castration-Resistant|Drug Therapy, Combination
Interventions: DRUG: TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL)
Status: UNKNOWN
Conditions: Percutaneous Nephrolithotomy (PCNL)|Prone Position|Prone-Flexed Position|Complication of Surgical Procedure
Interventions: PROCEDURE: Prone-Flexed PCNL|PROCEDURE: Prone PCNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gynodian® Depot in Women With Impaired Well-being
Status: COMPLETED
Conditions: Hormone Replacement Therapy
Interventions: DRUG: Gynodian® Depot (BAY86-5032)|DRUG: BAY86-4980
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Triangle Block: Early Mobilization and Postoperative Analgesia After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Anesthesia, Conduction|Pain, Postoperative|Ultrasonography, Interventional
Interventions: PROCEDURE: Apex Femoral Triangle Block|PROCEDURE: Femoral Nerve Block|PROCEDURE: Adductor Canal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of OLT1177 Gel to Treat Moderate to Severe OA Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: DRUG: Placebo Gel|DRUG: OLT1177 Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Acceptability and Benefits of Tracking Cardiac Pacemakers by Carelink Express
Status: TERMINATED
Conditions: Telecardiology
Interventions: DEVICE: Follow-up by Carelink express|OTHER: Follow-up according to the usual recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Botulinum Toxin to Improve Lower Blepharoplasty Scar
Status: UNKNOWN
Conditions: Other Degenerative Disorders of Eyelid and Periocular Area
Interventions: DRUG: Botulinum Toxin|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
Status: RECRUITING
Conditions: Pain, Chronic
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post Extraction Changes After Ridge Preservation Using Allogeneic Dentin Matrix Vs Demineralized Freeze Dried Allograft
Status: RECRUITING
Conditions: Socket Preservation
Interventions: BIOLOGICAL: Demineralized Dentin Matrix|BIOLOGICAL: Demineralized freeze-dried bone allograft (DFDBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Full Thickness Rotator Cuff Tear
Interventions: BIOLOGICAL: Mesenchymal stem cell augmentation in rotator cuff repair|PROCEDURE: Standard arthroscopic rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ocular Hypotensive Efficacy of AR-102
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: AR-102 0.003% Ophthalmic Solution|DRUG: AR-102 0.005% Ophthalmic Solution|DRUG: AR-102 0.01% Ophthalmic Solution|DRUG: AR-102 0.03% Ophthalmic Solution|DRUG: AR-102 Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Balance Study
Status: COMPLETED
Conditions: Mental Health Wellness 1|Work Related Stress
Interventions: DIETARY_SUPPLEMENT: Re-Focus "Verum" Tablets|DIETARY_SUPPLEMENT: Re-Focus "Placebo" Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Ketofol (Ketamine and Propofol Admixture) Versus Propofol as Induction Agents on Hemodynamic Parameters
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DRUG: Propofol|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Pharmacokinetics and Pharmacodynamics Study of Different Doses of Zoledronic Acid
Status: NOT_YET_RECRUITING
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Zoledronic Acid Injection|DRUG: Zoledronic Acid Injection|DRUG: Zoledronic Acid Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Comparing Two Surgical Treatment of Female Urodynamic Stress
Status: COMPLETED
Conditions: Female Stress Incontinence
Interventions: PROCEDURE: sub-urethral tape (TVT-O)|OTHER: stand standard mid-urethral sling (TVT-O)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial
Status: RECRUITING
Conditions: Severe Traumatic Brain Injury|Intracranial Hypertension
Interventions: PROCEDURE: External Lumbar drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bundle Approach on Foot Care Behaviors and Diabetic Wound Healing in Patients
Status: COMPLETED
Conditions: Wound|Diabetic Foot Ulcer|Ulcer
Interventions: OTHER: Bundla care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Impact of Direct and Surrogate Advertising and Compliance With the Bill With the Respect to Sale of Tobacco Products Around Educational Institutes
Status: UNKNOWN
Conditions: Assessing and Creating Awareness About the Tobacco Law
Interventions: BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Chromoendoscopy With Magnification in Coeliac Disease.
Status: UNKNOWN
Conditions: Celiac Disease
Interventions: DIAGNOSTIC_TEST: High-definition white light endoscopy (HD-WLE)|DIAGNOSTIC_TEST: HD-WLE plus I-Scan optical enhancement (OE) virtual chromoendoscopy with High-definition optical magnification (HD-OM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: SEL|DRUG: Placebo to match SEL 6 mg|DRUG: Placebo to match SEL 18 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia
Status: TERMINATED
Conditions: Lung Cancer|Precancerous Condition|Tobacco Use Disorder
Interventions: DRUG: defined green tea catechin extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Observational Study to Evaluate Secukinumab Treatment Effectiveness in Pediatric Patients With Active Juvenile Enthesitis-related or Psoriatic Arthritis
Status: NOT_YET_RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: OTHER: Secukinumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Status: COMPLETED
Conditions: Vitamin D Deficiency|Pre-Eclampsia
Interventions: DRUG: 400 IU Vitamin D3|DRUG: 4000 IU Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Irinotecan and Cyclosporine in Treating Patients With Metastatic, Advanced or Locally Recurrent Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: cyclosporine|DRUG: CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: PLX-PAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Effects of Implantable Gestrinone and Oral Dienogest in the Treatment of Endometriosis
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Implantable gestrinone|DRUG: Oral Dienogest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.
Status: COMPLETED
Conditions: Premature Ventricular Contraction
Interventions: DRUG: Tongmai Yangxin Pill (TMYXP)|DRUG: metoprolol tartrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low Level Laser Therapy on Improvement of Temporomandibular Joint Osteoarthritis
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorder
Interventions: RADIATION: Low level laser therapy|RADIATION: Low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control
Status: UNKNOWN
Conditions: Autosomal Dominant Polycystic Kidney Disease|Hypertension
Interventions: PROCEDURE: renal sympathetic denervation|DRUG: antihypertensive drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMINATED)
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: simvastatin|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: enzastaurin|DRUG: pemetrexed|DRUG: docetaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Pyridoxine hydrochloride|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Barlow's unIfied Protocol for emoTional Eating (BITE): a Pre-post Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Emotional Eating
Interventions: BEHAVIORAL: Barlow's Unified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimal Timing of Double-Wire Technique For Biliary Cannulation at ERCP
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography
Interventions: PROCEDURE: double-wire technique in patients undergoing ERCP with biliary cannulation|PROCEDURE: single-wire technique in patients undergoing ERCP with biliary cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Internet CBT for Trichotillomania and Skin Picking Disorder
Status: COMPLETED
Conditions: Trichotillomania|Excoriation (Skin-Picking) Disorder
Interventions: BEHAVIORAL: Internet delivered behavior therapy (I-BT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Enoxaparin|DRUG: Dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss
Status: RECRUITING
Conditions: Alopecia, Androgenetic
Interventions: DRUG: Clascoterone 5% solution|DRUG: Vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life on Peritoneal Dialysis Versus Hemodialysis in China
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Hemodialysis treatment (no specific device is defined)|DRUG: Peritoneal Dialysis treatment (no specific drug is defined)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: D/C/F/TAF|DRUG: DRV|DRUG: COBI|DRUG: FTC/TDF|DRUG: D/C/F/TAF Placebo|DRUG: DRV Placebo|DRUG: COBI Placebo|DRUG: FTC/TDF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Vitamin K Administration in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Vitamin K|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)|DRUG: Sildenafil|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome
Status: UNKNOWN
Conditions: Sjogren's Syndrome
Interventions: DRUG: Cyclosporin A|DRUG: Prednisone|DRUG: Placebo|DRUG: Calcium carbonate D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video Coaching of Physical Activity in Axial Spondyloarthritis
Status: RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: OTHER: Video coaching exercises|OTHER: Routine exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efﬁcacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section.
Status: COMPLETED
Conditions: Catheter Related Bladder Discomfort
Interventions: DRUG: hyoscine-n-butylbromide|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Nursing Intervention on Quality of Life, Sexual Function, and Self-esteem in Hysterectomized Women
Status: UNKNOWN
Conditions: Prevention of Complications Due to Hysterectomy
Interventions: BEHAVIORAL: Effectiveness of a nursing educational intervention on quality of life, sexual function, and self-esteem in hysterectomized women: a mixed method approach.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Asymmetrical Lateral Decubitus for Rotation of Occipitoposterior Fetal Position
Status: COMPLETED
Conditions: Fetal Occipitoposterior Position During the Labor
Interventions: OTHER: Asymmetrical Lateral Decubitus|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Morphinhydrochloricum|DRUG: Metoclopramide|DRUG: Ticagrelor|DRUG: Isotonic sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors
Status: COMPLETED
Conditions: Sexual Behavior|Alcohol Drinking|Sexual Aggression|Emotions
Interventions: BEHAVIORAL: High provocation manipulation|BEHAVIORAL: Low provocation manipulation|BEHAVIORAL: Alcoholic beverage|BEHAVIORAL: Non-alcoholic beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-hypnosis Training for Chronic Pain Management
Status: RECRUITING
Conditions: Hypnosis, Chronic Pain Management
Interventions: OTHER: Self-hypnosis|OTHER: Psycho-education and cognitive Bahavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Chemotherapy in Combination With IDO Inhibitor in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Docetaxel|OTHER: Placebo|DRUG: Indoximod|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chest Physiotherapy for Acute Bronchiolitis in Toddlers (BRONKINOU)
Status: COMPLETED
Conditions: Viral Bronchiolitis
Interventions: PROCEDURE: Chest Physiotherapy with Forced Expiratory Technique|PROCEDURE: Nasopharyngeal Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Status: UNKNOWN
Conditions: Muscle Damage
Interventions: OTHER: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Magnetic Resonance Imaging (MRI) of Pulp Regeneration
Status: COMPLETED
Conditions: Pulp Necroses|Periapical Lesion|Regeneration
Interventions: PROCEDURE: Regenerative endodontic procedures (REPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Losartan to Improve Hip Microfracture
Status: TERMINATED
Conditions: Hip Osteoarthritis|Hip Impingement Syndrome|Cartilage Damage|Fibrosis
Interventions: DRUG: Losartan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to COVID-19
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder|Moral Injury
Interventions: BEHAVIORAL: Medical Music|BEHAVIORAL: Narrative Writing|BEHAVIORAL: Prolonged Exposure Therapy|BEHAVIORAL: Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: M7824|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Four Doses of the Study Drug, HF1020 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: HF1020|DRUG: HF1020 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Faricimab (RO6867461) in Participants With Center-Involving Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Faricimab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis (BEST)
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: balloon-expandable valve|DEVICE: self-expanding valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
Status: COMPLETED
Conditions: Post-operative Pain|Total Shoulder Arthroplasty|Osteoarthritis of the Shoulder|Pain Management
Interventions: DRUG: Liposomal Bupivicaine 1.3%|DRUG: Bupivacaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of Secukinumab In Enthesitis of Psoriatic Arthritis Patients
Status: UNKNOWN
Conditions: Psoriatic Arthritis
Interventions: DRUG: Secukinumab 300 MG|DRUG: Secukinumab 150 MG|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|Male Breast Carcinoma|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Vibegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Enteral Nutrition Feeding in Alzheimer's Patients
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Conventional Care|DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: Nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 'Ai Pono Cooking Demonstrations
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes|Hypertension|Dyslipidemias|Overweight and Obesity
Interventions: OTHER: 'Ai Pono
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|RADIATION: intensity-modulated radiation therapy|RADIATION: tomotherapy|RADIATION: total marrow irradiation|RADIATION: total nodal irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Orthotic Use for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Orthotics|OTHER: Orthotics Plus Chiropractic Care|OTHER: Wait List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
Status: NOT_YET_RECRUITING
Conditions: Glioma|Low-grade Glioma|Low Grade Glioma of Brain|Glioma, Malignant|Glioma Intracranial
Interventions: DRUG: 18F-Fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: FC084CSA+Tislelizumab combination (dose escalation)|DRUG: RP2D of FC084CSA+Tislelizumab combination (dose expansion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Cocoa Ingestion Over Healthy Males Plasma Lipids Subjected to Peroxidative Conditions
Status: COMPLETED
Conditions: Lipid Peroxidation
Interventions: DIETARY_SUPPLEMENT: Cocoa powder berverage, dark chocolate bar|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Nivolumab for Non-Small Cell Lung Cancer (Stage III) Following Neoadjuvant Chemotherapy Plus Nivolumab and Definitive Concurrent Chemoradiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: OTHER: Neoadjuvant therapy|OTHER: Chemotherapy concurrent with radiotherapy|RADIATION: Radiotherapy|DRUG: Nivolumab|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Molecular Remission by ASO-qPCR After Bortezomib-dexamethasone (Vel/Dex) Followed by ASCT
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib + dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rozerem on Sleep Among People With Traumatic Brain Injury
Status: UNKNOWN
Conditions: Insomnia|Brain Injury
Interventions: DRUG: Ramelteon|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Autogenic and Reciprocal Inhibition, Muscle Energy Techniques in the Management of Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Group A (Control Group - Static Stretching + Standard Treatment)|OTHER: Group B (Autogenic Inhibition - PIR + Standard treatment)|OTHER: Group C (Reciprocal Inhibition - RI + Standard treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kin KeeperSM: Reducing Disparities Through Cancer Literacy and Screening
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Kin KeeperSM Cancer Prevention Intervention|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Aim of This Study is to Estimate the Discontinuation Rate of Low-dose Levonorgestrel-releasing Intrauterine System Due to Self-reported Unacceptable Menstrual Bleeding Pattern in Spanish Women Who Are Using it for the First Time How Intrauterine System for Long Acting Contraception
Status: COMPLETED
Conditions: Hormonal Intrauterine Contraception
Interventions: DRUG: Low-dose levonorgestrel intrauterine systems (LNG-IUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aminophylline Infusion on Pain Intensity After Ureterocopic Lithotripsy
Status: COMPLETED
Conditions: Aminophylline|Pain|Ureterocopic Lithotripsy
Interventions: DRUG: Aminophylline group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Noninvasive Electrical Brain Stimulation on Memory at Different Times of Day in Younger and Older Adults
Status: COMPLETED
Conditions: Effect of tDCS on Memory in Older and Younger Adults
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Drift-Reduction for Improved FFR Using Fiberoptic Technology (DRIFT) Study
Status: COMPLETED
Conditions: Left Anterior Descending Coronary Artery Stenosis
Interventions: DEVICE: OpSens Medical OptoWire|PROCEDURE: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Lymphoma, Non-Hodgkin's|Leukemia, T-Cell|Leukemia, B-Cell
Interventions: DRUG: Dexamethasone|DRUG: Panobinostat|DRUG: Liposomal vincristine|DRUG: Mitoxantrone|DRUG: Peg-asparaginase|DRUG: Bortezomib|DRUG: Intrathecal Triples|DRUG: High-dose methotrexate|DRUG: 6-Mercaptopurine|DRUG: High-dose cytarabine|DRUG: Nelarabine|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Atomoxetine Plus Either Comparator or Placebo in Children With ADHD Who Haven't Responded to Stimulant Therapy
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: Methylphenidate Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comp Granisetron Midazolam Comb in Lap Children
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Granisetron|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology-2 (PVC-RAM-2) Trial
Status: NOT_YET_RECRUITING
Conditions: Surgery|Perioperative Complication
Interventions: COMBINATION_PRODUCT: Virtual care with remote automated monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Postoperative Pain of Two Bioceramic Root Canal Sealers With Obturation Techniques
Status: COMPLETED
Conditions: Effect of Material and Technique
Interventions: OTHER: single cone technique using TotalFill BC Sealer|OTHER: warm vertical compaction technique using TotalFill BC Sealer HiFlow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Acceptable Taste and to Estimate the Amount of Atazanavir and Cobicistat in the Body When Taken as a Combination Product Versus When Taken as Separate Products at the Same Time
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Atazanavir/Cobicistat|DRUG: Reyataz Atazanavir|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck Tumor
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: COMBINATION_PRODUCT: TumoCure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Mindful Meditation Practice in Improving Quality of Life in Patients With Cancer Undergoing Radiation Therapy
Status: TERMINATED
Conditions: Malignant Neoplasm
Interventions: PROCEDURE: Meditation therapy|OTHER: Quality-of-life assessment|OTHER: Questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mycophenolate Mofetil, Tacrolimus, Daclizumab, and Donor Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: daclizumab|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive Remediation Therapy on Schizophrenia Patients Through Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Remediation Therapy|BEHAVIORAL: Psychoeducation|OTHER: Healthy controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)
Status: WITHDRAWN
Conditions: T Acute Lymphoblastic Leukemia|T Lymphoblastic Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Calaspargase Pegol|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Dexamethasone|DRUG: Doxorubicin|PROCEDURE: Echocardiography|PROCEDURE: Lumbar Puncture|DRUG: Mercaptopurine|DRUG: Methotrexate|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Navitoclax|DRUG: Nelarabine|DRUG: Pegaspargase|PROCEDURE: Positron Emission Tomography|DRUG: Thioguanine|DRUG: Venetoclax|DRUG: Vincristine|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Mucositis
Interventions: DRUG: Drug: GC4419|RADIATION: Intensity-modulated radiation therapy (IMRT)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Volar Fibroblast Injection Into the Stump Site of Amputees
Status: RECRUITING
Conditions: Amputation|Skin Wound|Stem Cell
Interventions: BIOLOGICAL: Autologous Skin Fibroblasts|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Copenhagen Plank on Aductional Strenght and Vertical Jump in Female Football Players
Status: COMPLETED
Conditions: Groin Injury|Muscle Injury
Interventions: PROCEDURE: Copenhagen plank
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Evaluation of Herbal and Allopathic Drugs for the Treatment of Chronic Diarrhea
Status: COMPLETED
Conditions: Chronic Diarrhea
Interventions: DRUG: Metronidazole|DRUG: Entoban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiometabolic Therapy (RMT) With 177Lu PSMA 617 in Advanced Castration Resistant Prostate Cancer (CRPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration Resistant Prostate Cancer|68Ga-PSMA PET/CT Positive
Interventions: DRUG: 177Lu-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular Rehabilitation App for Adults With Dizziness Related to mTBI
Status: NOT_YET_RECRUITING
Conditions: Mild Traumatic Brain Injury|Dizziness
Interventions: BEHAVIORAL: Vestibular Rehabilitation Therapy (VRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Chemotherapy on Axillary Lymph Node Metastases in Stage II Breast Cancer: A Prospective Randomized Trial
Status: COMPLETED
Conditions: Breast Neoplasm|Neoplasm Metastasis
Interventions: DRUG: preoperative dose intense chemotherapy (FLAC/G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT