pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Efficacy and Safety LMF237 in Patients With Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Vildagliptin Monotherapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LMF237 50/250 mg|DRUG: LMF237 50/500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-Augmented Insulin-Pump Therapy in New-onset Diabetes After Transplantation
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DRUG: Insulin lispro, Humalog (Eli Lilly) in insulin pump|DRUG: Human insulin isophane, Humulin N (Eli Lilly)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NG101m Adjuvant Therapy in Glioblastoma Patients
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: RADIATION: Intensity-modulated radiation therapy|DRUG: Temozolomide|DRUG: NG101m
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRE Surgery reHABilitation for Spinal Stenosis
Status: COMPLETED
Conditions: Low Back Pain|Rehabilitation|Physiotherapy
Interventions: OTHER: Supervised abdominal exercises and stationary biking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
Status: COMPLETED
Conditions: Anesthesia, General|Anesthesia, Spinal|Umbilical Cord
Interventions: OTHER: General anesthesia|OTHER: Spinal anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Olesoxime in Patients With Stable Relapsing Remitting Multiple Sclerosis Treated With Interferon Beta.
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: olesoxime (TRO19622)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Accuracy and Precision of the BGStar® and iBGStar® Blood Glucose Meter in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Comparison of different Blood Glucose Meters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Proof-of-concept of a Robotic Knee Exoskeleton in Healthy Subjects and Hemiparetic Patients During Gait.
Status: COMPLETED
Conditions: Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Interventions: DEVICE: Exoskeleton assisted gait on a treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety Study of Fluticasone Furoate (FF)/GW642444 Inhalation Powder and the Individual Components in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF Inhalation Powder|DRUG: FF/GW642444 Inhalation Powder|DRUG: GW642444 Inhalation Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker-based Cockroach Sublingual Immunotherapy Study (BioCSI)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Asthma
Interventions: BIOLOGICAL: Glycerinated German Cockroach Allergenic Extract|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-placental Intrauterine Device Insertion During Cesarean Section
Status: COMPLETED
Conditions: Intrauterine Device Migration
Interventions: PROCEDURE: Intrauterine device insertion|PROCEDURE: Cesarean section|PROCEDURE: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Functional Collagen Scaffold for Laryngeal Soft Tissue Regeneration
Status: UNKNOWN
Conditions: Glottic Insufficiency
Interventions: BIOLOGICAL: Functional collagen scaffold transplantation|BIOLOGICAL: Autologous adipose cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Partial Replicated Crossover Clinical Study to Compare Pharmacokinectic Characteristics of Eperisone Hydrochloride and Aceclofenac With HCP1104 Treatment to Those of Co-administration of Eperisone Hydrochloride 50mg Tablet and Aceclofenac 100mg Tablet in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP1104 / Mulex Tab. and Airtal Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Responses Induced by a HIV Vaccine
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: AIDSVAX B/E|BIOLOGICAL: AIDSVAX B/E Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rex Robot Assisted Rehabilitation to Enhance Balance and Mobility for People With Multiple Sclerosis, Clinical and Biomarker Study - RAPPER IV
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Rex robotic assisted balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure
Status: RECRUITING
Conditions: Covid19
Interventions: DRUG: Pulmozyme/ Recombinant human deoxyribonuclease (rh-DNase)|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation and Neuromuscular Electrical Stimulation in Persons With SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: NMES|DIETARY_SUPPLEMENT: Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-ranging Study to Evaluate the Effectiveness and Tolerability of MK0736 in Patients With Type 2 Diabetes Mellitus (T2DM) and Hypertension (0736-007)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: DRUG: MK-0736|DRUG: Comparator: Placebo|DRUG: Comparator: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis
Status: COMPLETED
Conditions: Sepsis|Necrotizing Enterocolitis|Meningitis|Pneumonia
Interventions: DIETARY_SUPPLEMENT: Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Malignant Solid Neoplasm|Metastatic Melanoma|Unresectable Melanoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Dabrafenib|PROCEDURE: Echocardiography|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Navitoclax|OTHER: Pharmacological Study|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Supaglutide in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Supaglutide injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Double-blind Controlled Trial of Use of Dydrogesterone in Threatened Miscarriage
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Dydrogesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Liquid Versus Solid Forms of Sugars and Whey Protein
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: OTHER: Compare the effect of solid vs. liquid forms of sugars on satiety and food intake|OTHER: the effect of solid vs. liquid forms of gelatin on appetite and food intake|OTHER: The effect of solid vs. liquid forms of whey protein on food intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Nutrition Poor|Physical Activity|Weight Loss
Interventions: BEHAVIORAL: Healthy Frio In-Person Family-focused Intervention|BEHAVIORAL: Healthy Frio Remote Technology Family-focused Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Persistence of the Complete Molecular Remission After Stopping Imatinib Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Myeloid Leukemia, Chronic
Interventions: BEHAVIORAL: Imatinib ending
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-intensity Shockwave Therapy for Post-radical Prostatectomy Erectile Dysfunction
Status: RECRUITING
Conditions: Erectile Dysfunction Following Radical Prostatectomy
Interventions: DEVICE: Low-Intensity Shockwave therapy (LiSWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Visant Medical Canalicular Plug|DEVICE: Commercially available canalicular plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of AP30663 for Cardioversion in Participants With Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: AP30663|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal
Status: COMPLETED
Conditions: Pharmacokinetics|Tolerability
Interventions: DRUG: Androxal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block Versus Erector Spinae Plane Block for Analgesia in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: TPVB|PROCEDURE: ESPB|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OSA-ACS Project: Association of OSA and CPAP Therapy With Outcomes in ACS Patients
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Adult|Acute Coronary Syndrome
Interventions: OTHER: Patients with OSA based on sleep study|OTHER: Patients without OSA based on sleep study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Articaine 4% Efficacy and Safety in Extraction and Pulpotomy of Primary Molars of Children Below the Age of Four Years
Status: UNKNOWN
Conditions: Pain|Behavior
Interventions: DRUG: Lidocain hydrochloride 2 % with epinephrine|DRUG: Articaine chloride 4% with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Comparison of Adjuvant Chemotherapy W/High-Dose Cyclophosphamide Plus Doxorubicin (AC) vs Sequential Doxorubicin Fol by Cyclophosphamide (A-C) in High Risk Breast Cancer Patients With 0-3 Positive Nodes (Intergroup, CALGB 9394)
Status: COMPLETED
Conditions: High Risk|Breast Cancer|Positive Nodes|Cyclophosphamide|Doxorubicin
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: G-CSF|DRUG: tamoxifen|DRUG: ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Control Study to Asses the Role of Negative Pressure Wound Therapy (NPWT) in the Management of Wound in Surgical Patient
Status: UNKNOWN
Conditions: Wound Infection|Wound Complication
Interventions: DEVICE: PICO + Acticoat group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electrophilic Fatty Acid Derivatives in Asthma
Status: COMPLETED
Conditions: Asthma|Electrophilic Fatty Acids
Interventions: DRUG: Aspirin|DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Depo-Provera: Bone Mineral Density and Total Body Calcium in Adolescent DP150CI Users and Non-Hormonal Contraception
Status: COMPLETED
Conditions: Contraception|Bone Density
Interventions: DRUG: Depo-Provera Contraceptive Injection - DP150CI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Field Magnetic Resonance Imaging Assessment With Outpatients
Status: RECRUITING
Conditions: Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound
Interventions: DIAGNOSTIC_TEST: Hyperfine MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega-3 Fatty Acids and/or Multi-domain Intervention in the Prevention of Age-related Cognitive Decline
Status: COMPLETED
Conditions: Frail Elderly Subjects
Interventions: DIETARY_SUPPLEMENT: omega-3|BEHAVIORAL: multi-domain intervention|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BMS - Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Dapagliflozin in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo matching Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Biologic Effects of an Eicosapentaenoic (EPA)-Enriched Oil
Status: COMPLETED
Conditions: Heart Disease
Interventions: DIETARY_SUPPLEMENT: EPA 600|DIETARY_SUPPLEMENT: EPA 1800|DIETARY_SUPPLEMENT: Olive Oil|DIETARY_SUPPLEMENT: DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a New Treatment in Combination With Laser for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone|DRUG: Sham injection|PROCEDURE: Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study To Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors
Status: TERMINATED
Conditions: Lymphoma, Large B-Cell, Diffuse|Lymphoma, Mantle-Cell|Lymphoma, Follicular|Cancer|Neoplasm|Tumor|Lymphoma, Malignant|Lymphoma, B-cell|Lymphoma, Non-Hodgkin|B-Cell Chronic Lymphocytic Leukemia|B-Cell Leukemia, Chronic|B-Lymphocytic Leukemia, Chronic|Chronic Lymphocytic Leukemia|Leukemia, Lymphocytic, Chronic|Leukemia, Lymphocytic, Chronic, B Cell|Myelofibrosis|Chronic Idiopathic Myelofibrosis|Idiopathic Myelofibrosis|Lymphoma, T Cell, Peripheral|Peripheral T-Cell Lymphoma|T-Cell Lymphoma, Peripheral
Interventions: DRUG: ASN002 Dose Escalation|DRUG: ASN002 RD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nilotinib Versus Imatinib in GIST Patients
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: Nilotinib (AMN107)|DRUG: imatinib (STI571)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Implantation Under Echography of Fiducial Markers in the Intraprostatic Lesion and Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Goldlock|DEVICE: Visicoil smallest size|DEVICE: Visicoil larger size|DEVICE: Bard goldmarker smallest size|DEVICE: Bard goldmarker larger size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rTMS Plus Vestibular Rehabilitation as an Adjunct Treatment for Fall Risk and Postural Instability for Chronic Vestibular Dizziness Patients/ Chronic Labyrinthitis
Status: COMPLETED
Conditions: Peripheral Vestibular Disorders
Interventions: DEVICE: rTMS group|DEVICE: placebo rTMS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Dose Expansion Study of XMT-1536 in Cancers Likely to Express NaPi2b
Status: COMPLETED
Conditions: Platinum Resistant Ovarian Cancer|Non-Small Cell Adenocarcinoma
Interventions: DRUG: upifitamab rilsodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings
Status: COMPLETED
Conditions: Post-Traumatic Headache|Acute Pain
Interventions: DRUG: IV titrated morphine|DRUG: Low dose nebulised morphine|DRUG: High dose nebulised morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Autologous Mesenchymal Stem Cells Transplantation in Thoracolumbar Chronic and Complete Spinal Cord Injury Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Autologous mesenchymal cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MRI-conditional 12-lead ECG
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: 12-lead ECG monitoring device (MiRTLE Medical)|DEVICE: 3-lead ECG gating system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation
Status: ACTIVE_NOT_RECRUITING
Conditions: Barrett Esophagus
Interventions: DRUG: Aspirin|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Imatinib Mesylate in Treating Patients With Refractory or Relapsed Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer, or Ovarian Low Malignant Potential Tumor
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yellow Pea Protein and Fibre and Short Term Food Intake
Status: COMPLETED
Conditions: Obesity|Type II Diabetes Mellitus|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: yellow pea protein|DIETARY_SUPPLEMENT: yellow pea fiber|DIETARY_SUPPLEMENT: Control Tomato Soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness and Cost-effectiveness of Chuna Manual Therapy for Chronic Neck Pain
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: PROCEDURE: Chuna manual therapy|DRUG: Conventional medication|PROCEDURE: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Interest of Belatacept as a Non-nephrotoxic Immunosuppressive Treatment in Cardiac Transplant Patients at Risk of Chronic Renal Failure (BELACOEUR)
Status: RECRUITING
Conditions: Heart Transplant Failure
Interventions: DRUG: Belatacept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Placebo|DRUG: PH-797804|DRUG: PH-797804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer|Unresectable Pancreatic Cancer|Metastatic Colorectal Cancer
Interventions: BEHAVIORAL: Usual chemotherapy education (CE)|BEHAVIORAL: Chemotherapy education intervention (CEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dimethyldiguanide Combined With Aromatase Inhibitor (AI) in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: AI plus Dimethyldiguanide|DRUG: Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D During In Vitro Fertilisation (IVF) - A Prospective Randomized Trial
Status: UNKNOWN
Conditions: Pregnancy Complication
Interventions: DIETARY_SUPPLEMENT: Ergocalciferol|DIETARY_SUPPLEMENT: Ergocalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of Autologous Whole Blood Injection for the Treatment of Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fascitis
Interventions: BIOLOGICAL: Injection of autologous whole blood to the plantar fascia|DEVICE: Injection of normal saline to the plantar fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Adjuvant Trial in Patients With Stage I-III Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma|Merkel Cell Carcinoma, Stage I|Merkel Cell Carcinoma, Stage II|Merkel Cell Carcinoma, Stage III|Neuroendocrine Tumors|Carcinoma Neuroendocrine Skin
Interventions: DRUG: Avelumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Women With Locally Recurrent or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: therapeutic autologous dendritic cells|BIOLOGICAL: trastuzumab|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing 4.0 mg.Kg-1 Sugammadex With Placebo in the Reversal of Profound Neuromuscular Blockade (P05767)
Status: COMPLETED
Conditions: Anesthesia|Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: 0.9% sodium chloride (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality as a Substitute for Procedural Sedation During Epidural Steroid Injections
Status: COMPLETED
Conditions: Lower Back Pain|Lumbar Radiculopathy
Interventions: DEVICE: Virtual reality|DRUG: Intravenous sedation|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: STENTYS Self-expanding Versus Balloon-expandable Stent in Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: STEMI
Interventions: DEVICE: Stentys coronary stent|DEVICE: Balloon-expandable stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three Continuation Therapies After ECT Concerning Efficacy and Cognition in Severly Depressed Patients
Status: COMPLETED
Conditions: Depression|Major Depression
Interventions: DRUG: TCAs, SSRIs, NARIs, SNRIs, Lithium|PROCEDURE: Electroconvulsive therapy|BEHAVIORAL: Cognitive behavioral group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Compression Maneuver of Upper Arm to Reduce Axillary Brachial Plexus Block Onset Time
Status: UNKNOWN
Conditions: Forearm Injuries|Hand Injuries
Interventions: PROCEDURE: Ultrasound guided axillary plexus block|PROCEDURE: Intermittent pneumatic compression maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: National Multicenter, Controlled, Single-blind Study With Two Parallel Groups Evaluating the Safety and Efficacy of Sequential Treatment With Mitoxantrone and Interferon Versus Interferon Alone in Patients With Strong Risk of Progression in the Initial Phase of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta 1a|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of an NR2B NMDA Antagonist, CP-101,606, in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: NR2B NMDA Antagonist CP-101,606 (traxoprodil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity, and Immunogenicity of Inactivated Influenza A/H7/N7 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A/H7N7 Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Monthly Text Message Reminder After Training on Beliefs and Practice Behaviors Regarding Women's Breast Self Examination: Randomized Controlled Study
Status: UNKNOWN
Conditions: Women's Breast Self Examination Beliefs|Women's Breast Self Examination Practice
Interventions: BEHAVIORAL: Monthly reminder message about breast self-exam.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Pin Removal in Children - is Analgesia Necessary?
Status: COMPLETED
Conditions: Elbow Fracture
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen|OTHER: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Mulligan Bent Leg Raise vs Active Release Technique in Patients With Hamstring Tightness
Status: COMPLETED
Conditions: Hamstring Injury
Interventions: OTHER: Active Release Technique|OTHER: Mulligan Bent Leg Raise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation Therapy Combined With Static Magnetic Field in CrossFit® Athletes
Status: COMPLETED
Conditions: Muscle Strength
Interventions: DEVICE: Effective PBMT/sMF|DEVICE: Placebo PBMT/sMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Toripalimab Plus Neoadjuvant Chemotherapy Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Toripalimab|DRUG: Paclitaxel-albumin|DRUG: Nedaplatin|RADIATION: radiation therapy at a total dose 60 Gy|DRUG: Capecitabine|RADIATION: radiation therapy at a total dose 50 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Danicopan|DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in the Treatment of Postoperative Pain in Patients Undergoing Gynaecologic Laparoscopic Surgery
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Precision Psychiatry Continuity Clinic Project
Status: COMPLETED
Conditions: Depressive Disorders|Depressive Symptoms|Anxiety Disorders and Symptoms|Psychological Distress|Mood Disorders
Interventions: OTHER: Feedback Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Effect of Transcutaneous Electrical Nerve Stimulation (TENS) in Postmenopausal Women
Status: UNKNOWN
Conditions: Menopause
Interventions: DEVICE: Transcutaneous Elevtrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in Patients With Uncontrolled Blood Pressure
Status: TERMINATED
Conditions: Blood Pressure
Interventions: RADIATION: Radiation Dose 25 Gy|RADIATION: Radiation Dose 50 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interventional Strategy in Tackling Emerging Non-alcoholic Fatty Liver Disease in Childhood Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Tocotrienol-rich fraction vitamin E (TRF)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Improvement Among Medicaid Enrollees
Status: TERMINATED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Experimental: AIMS program - patient|OTHER: No Intervention/Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Famitinib in Combination With Adebrelimab for the Treatment of Advanced Thyroid Cancer
Status: NOT_YET_RECRUITING
Conditions: Thyroid Cancer
Interventions: COMBINATION_PRODUCT: 20 mg Famitinib & 1200 mg Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Preconditioning and Postconditioning on Lung Injury During Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: PROCEDURE: remote ischemic preconditioning and postconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Periodized and Autoregulated Resistance Training in Haematological Cancer Patients During the Treatent.
Status: UNKNOWN
Conditions: Fatigue|Leukemia|Lymphoma|Physical Disability
Interventions: OTHER: Standard protocol Leukemia|OTHER: Periodic Resistance Training Program Leukemia|OTHER: Standard protocol Lymphoma|OTHER: Periodic Resistance Training Program Lymphoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Effectiveness of a Digital Therapeutics in Adults Diagnosed With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: CT-152 - Digital Therapeutic|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Naltrexone in Symptomatic Inflammatory Bowel Disease
Status: WITHDRAWN
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: DRUG: Low dose naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avapritinib With Decitabine in Patients With SM-AHN
Status: RECRUITING
Conditions: Systemic Mastocytosis With an Associated Hematologic Neoplasm
Interventions: DRUG: Avapritinib|DRUG: Decitabine|COMBINATION_PRODUCT: Decitabine/Cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Human Trial to Assess the Low Density Lipoprotein Cholesterol (LDL-C) Lowering Effect of Soy
Status: COMPLETED
Conditions: Hypercholesterolemia|Cardiovascular Disease|CRP
Interventions: OTHER: Standardized soy containing muffin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TomVasc - Vascular Effects of Tomato Extract
Status: COMPLETED
Conditions: Ischemic Heart Disease|Transient Ischemic Attack|Stroke|Peripheral Vascular Disease
Interventions: DIETARY_SUPPLEMENT: Ateronon|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments
Status: NOT_YET_RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: ProTaper Gold file system|PROCEDURE: OneShape file system|PROCEDURE: TruNatomy file system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Influence of Atorvastatin on the Repolarisation Phase of Cardiomyocytes
Status: UNKNOWN
Conditions: Heterogeneity of Cardiomyocytes Repolarisation|Autonomic Changes of Cardiomyocytes Repolarisation
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-man Sirolimus-eluting Prolim® Stent Registry
Status: COMPLETED
Conditions: Sirolimus-eluting Stainless Steel Coronary Stent Prolim®
Interventions: DEVICE: Prolim stent deployment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Your Health: A Workplace Healthy Lifestyle Program
Status: UNKNOWN
Conditions: Lifestyle|Exercise|Nutrition
Interventions: BEHAVIORAL: Health Risks assessement|BEHAVIORAL: Web-based health discussions|BEHAVIORAL: SOScuisine website|BEHAVIORAL: Health screening|BEHAVIORAL: Closing events|BEHAVIORAL: Coaching|BEHAVIORAL: Social Health platform|BEHAVIORAL: Accelerometer provided
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Aggressive Versus Initially Conservative Therapy in Elderly Patients With Non-ST-Elevation Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: systematic coronary intervention|OTHER: coronary intervention only for cases refractory to medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants
Status: COMPLETED
Conditions: Influenza Infection
Interventions: DRUG: TAK-850 0.5 mL injection|DRUG: TAK-850 0.25 mL injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of Diagnostic Accuracy of Endoscopic Ultrasound-guided Fine Needle Aspiration and Biopsy (EUS-FNAB) in the Absence of Rapid Onsite Evaluation
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS-FNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 1B Intravesical Administration of SCH 721015 (Ad-IFNa) in Admixture With SCH 209702 (Syn3) for The Treatment of BCG Refractory Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: SCH 721015
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Phase 1 Dose Finding Study of TRC105 in Patients With Solid Cancer
Status: COMPLETED
Conditions: Cancer|Neoplasm Metastasis
Interventions: DRUG: TRC105 chimeric anti-CD105 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeatability and Reproducibility of the ArcScan Insight 100 VHF Digital Ultrasound
Status: SUSPENDED
Conditions: Corneal Thickness Measurement|Epithelial Thickness Measurement|Anterior Eye Segment Measurements
Interventions: DEVICE: ArcScan Insight 100 very high-frequency digital ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection
Status: TERMINATED
Conditions: Esophagogastric Tumors|Gastric Cancer|Gastric Tumor|Esophageal Cancer|Esophageal Neoplasms|Esophageal Tumor|GastroEsophageal Cancer|Gastroesophageal Junction Adenocarcinoma|Gastroesophageal Junction Tumor|Gastroesophageal Junction Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interrupting Sitting With High Intensity Exercise on Vascular Function in Adolescents Before and After a Mixed Meal
Status: TERMINATED
Conditions: Cardiovascular Risk Factor|Endothelial Dysfunction
Interventions: BEHAVIORAL: Interrupting 3 hours of prolonged sitting with high intensity interval exercise|BEHAVIORAL: 3 hours of prolonged sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Re-irradiaTion With and Without HYPERthermia: Toxicity, Quality of Life and Survival in Patients With Locoregional Recurrent Breast Cancer
Status: RECRUITING
Conditions: Locoregional Recurrence|Breast Cancer|Re-irradiation|Hyperthermia
Interventions: OTHER: No interventions, patient-reported outcomes (PROMs) and toxicity will be collected in both groups.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Transcranial Magnetic Stimulation (TMS) and Cognitive Training for Alzheimer Patients
Status: COMPLETED
Conditions: Alzheimer Disease, Early Onset
Interventions: DEVICE: TMS stimulation|DEVICE: Sham comparator|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD)
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: DRUG: ARB|DRUG: Pentoxifylline|DRUG: Placebo (for Pentoxifylline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Stroke Primary Prevention Trial
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: Enalapril/folic acid|DRUG: Enalapril maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study Of An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In Patients With Advanced Cancer
Status: TERMINATED
Conditions: Neoplasms|Lymphoma, Non-Hodgkin
Interventions: DRUG: AG-024322
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Window of Opportunity Trial of Dasatinib in Operable Triple Negative Breast Cancers With nEGFR
Status: TERMINATED
Conditions: Breast Neoplasms|Triple Negative Breast Neoplasms
Interventions: DRUG: Dasatinib|PROCEDURE: Conventional Surgery|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerability, Safety, & Efficacy of Argon Plasma Coagulation to Treat Anal Intraepithelial Neoplasia in HIV-Positive Men
Status: COMPLETED
Conditions: Anus Neoplasms|HIV Infections
Interventions: PROCEDURE: Argon Plasma Coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Training With Sensory Integration On The Gross Motor Functions Of Lower Limb
Status: COMPLETED
Conditions: Cerebral Palsy Spastic Diplegia
Interventions: OTHER: VR training + Sensory Integration therapy + conventional therapy|OTHER: VR training + conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating Satisfying Engagement in Daily Life Through Coaching for People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Quality of Life
Interventions: BEHAVIORAL: Occupational Performance Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Occupational Status and Hematological Disease
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Myelodysplastic Syndrome|Chronic Thrombocytopenia|Hodgkin Disease
Interventions: BEHAVIORAL: Study questionnaire|BEHAVIORAL: SF-36 Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Adefovir Dipivoxil for Korean Patients With Chronic Hepatitis B(CHB) Who Have Completed ADF 103814
Status: COMPLETED
Conditions: Hepatitis B, Chronic|Chronic Hepatitis B
Interventions: DRUG: adefovir dipivoxil 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT