pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Hyperemic Efficacy Between Nicorandil and Adenosine for Fractional Flow Reserve (FFR) Measurement
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: OTHER: Maximal Hyperemia with Adenosine Followed by Nicorandil|OTHER: Maximal Hyperemia with Nicorandil Followed by Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study to Compare How Much Semaglutide is Found in the Blood With Different Tablets of Oral Semaglutide in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Semaglutide J|DRUG: Semaglutide C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Characteristics, Management and Prognosis of Patients Developing Intraoperative Cardiac Arrest During Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Cardiac Arrest, Transcatheter Aortic Valve Implantation
Interventions: OTHER: follow up and record
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction
Status: WITHDRAWN
Conditions: Peyronie Disease|Penile Curvature|Erectile Dysfunction
Interventions: DRUG: Collagenase Clostridium Histolyticum|DEVICE: Duolith SD1 T-TOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RESTORE Declined Livers Study
Status: RECRUITING
Conditions: Liver Diseases|Surgery|Transplant; Failure, Liver
Interventions: DEVICE: Declined liver in Normothermic Machine Perfusion (NMP)|PROCEDURE: Standard cold preservation of liver
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia
Status: COMPLETED
Conditions: Good Prognosis Metastatic Gestational Trophoblastic Tumor|Hydatidiform Mole|Non-Metastatic Gestational Trophoblastic Tumor|Uterine Corpus Choriocarcinoma
Interventions: BIOLOGICAL: Dactinomycin|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Newly Developed Ostomy Products in Subjects With Ileostomy
Status: COMPLETED
Conditions: Stoma Ileostomy
Interventions: DEVICE: Coloplast test product|DEVICE: SenSura Convex Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Specialized Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Assisted Plane Block (LAPB) Trial
Status: TERMINATED
Conditions: Opioid Use
Interventions: DRUG: Bupivacaine|DRUG: Exparel 266 milligram Per 20 ML Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: Dolutegravir/abacavir/lamivudine FDC|DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Tenofovir/emtricitabine FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of DES Platforms on Markers of Endothelial Damage and Inflammation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: platinum chromium everolimus-eluting stent|DEVICE: cobalt chromium everolimus-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of the Tolerability of Two Facial Cleansing Routines for Mild to Moderate Acne
Status: COMPLETED
Conditions: Acne
Interventions: COMBINATION_PRODUCT: Geologie Acne Regimen - one side of face|COMBINATION_PRODUCT: Proactive Acne Regimen - other side of face
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of an Advanced Hybrid Closed Loop System Using Lyumjev With the Tandem t:Slim X2 Insulin Pump With Control-IQ Technology in Adults, Adolescents and Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: t:slim X2 insulin pump with Control-IQ technology 1.5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of (18F-FCH) Comparing With (18F-FDG) for Detecting Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Disease
Interventions: DRUG: 18F- fluorocholine|DRUG: 18F- fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Trial-Based Cognitive Therapy and Behavioral Activation in Treatment of Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Trial based cognitive therapy|BEHAVIORAL: Behavioral Activation|DRUG: Antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain
Status: COMPLETED
Conditions: Corneal Pain|Chronic Pain|Neuropathic Pain
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate ERAS-801 in Patients With Recurrent Glioblastoma (THUNDERBBOLT-1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: ERAS-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dialectical Behavior Therapy Versus CAMS-informed Supportive Psychotherapy on Self Harming Behavior
Status: COMPLETED
Conditions: Borderline Personality Disorder|Suicide
Interventions: BEHAVIORAL: DBT|BEHAVIORAL: CAMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preservation of Endopelvic Fascia: Effects on Postoperative Incontinence and Impotence. Randomized Clinical Trial.
Status: COMPLETED
Conditions: Prostatic Neoplasms|Urinary Incontinence|Erectile Dysfunction
Interventions: PROCEDURE: Preservation (endopelvic fascia)|PROCEDURE: Opening (endopelvic fascia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Peanut Butter on Sleep Quality and Daily Energy Levels in Fire Fighters
Status: COMPLETED
Conditions: Sleep|Body Composition|Blood Pressure|Physical Activity
Interventions: DIETARY_SUPPLEMENT: Peanut Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Laser Intervention in Early Age-Related Macular Degeneration Study
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DEVICE: 2RT nanosecond laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: OC-01 (varenicline) nasal spray|DRUG: Placebo (vehicle control) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Vascular Health in Children
Status: COMPLETED
Conditions: Obesity|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This is an Early Study to Investigate the Effect of Gimatecan® in Adults With Solid Tumor
Status: COMPLETED
Conditions: Solid Malignancies
Interventions: DRUG: Gimatecan® (ST-1481)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fit Families Program for Families of Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: 12-week FMS Intervention|BEHAVIORAL: Physical Activities & Activity Booklets (via FitFamilies app)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Fistula Versus Graft in Elderly Patients
Status: TERMINATED
Conditions: End Stage Renal Disease|Arteriovenous Fistula|Arteriovenous Graft
Interventions: PROCEDURE: Arteriovenous Fistula (AVF)|PROCEDURE: Arteriovenous Graft (AVG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Toxicity Study of Pomalidomide and Dexamethasone in Patients Who Have Relapsed After Exposure to Lenalidomide and Bortezomib
Status: UNKNOWN
Conditions: Multiple Myeloma|Relapse After Use of Lenalidomide and Bortezomib
Interventions: DRUG: Pomalidomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-escalation Protocols in HPV-related Oropharyngeal Carcinoma in Chinese Populations
Status: UNKNOWN
Conditions: Oropharyngeal Carcinoma|De-escalation
Interventions: OTHER: Toxicities reduced treatment|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
Status: COMPLETED
Conditions: Angina Pectoris|Coronary Artery Disease|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Healthy Mothers-Healthy Children Nutrition
Status: COMPLETED
Conditions: Overweight and Obesity|Adiposity|Nutrient; Excess|Physical Activity
Interventions: BEHAVIORAL: Nutrition and Physical Activity Intervention|OTHER: English for Second Language Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intradialytic Kinetics of Cardiac Biomarkers During Hemodialysis and Hemodiafiltration
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: DEVICE: High-flux hemodialysis|DEVICE: Post-dilution hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Avastin (Bevacizumab) Plus Crossover Fluoropyrimidine-Based Chemotherapy in Patients With Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Chemotherapy|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Breath Hydrogen Exhalation After a Test Meal Containing Isomaltulose or Sucrose in Infants
Status: UNKNOWN
Conditions: Malabsorption
Interventions: DIETARY_SUPPLEMENT: Isomaltulose|DIETARY_SUPPLEMENT: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia
Status: COMPLETED
Conditions: Anesthesia With Use of LMA (Laryngeal Mask Airway)
Interventions: DRUG: Desflurane|DRUG: Sevoflurane|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Donafenib in the Treatment of Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Donafenib Tosilate Tablets|DRUG: Toripalimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Neuropathy;Peripheral|Chemotherapy-induced Peripheral Neuropathy|Neuropathy
Interventions: DEVICE: Voxx Human Performance Technology Socks|DEVICE: Placebo Socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Sexual Functions With Validated Measurement Scale After Transvaginal Extraction of Tissue by Laparoscopic Surgery With Uterus Preservation (FSF-TVE)
Status: NOT_YET_RECRUITING
Conditions: Transvaginal Tissue Extraction
Interventions: PROCEDURE: Transvaginal tissue retrieval via a posterior colpotomy|PROCEDURE: Transabdominal retrieval via trocar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Activity-Dependent Transspinal Stimulation in SCI
Status: TERMINATED
Conditions: Spinal Cord Injuries|Paraplegia, Spinal|Tetraplegia/Tetraparesis|Paraplegia, Spastic
Interventions: OTHER: Robotic gait training|DEVICE: Robotic gait training and low-frequency transspinal stimulation|DEVICE: Robotic gait training and high-frequency transspinal stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Patient-Reported Quality of Life and Effectiveness on Control of Bleeding in Adult Participants With Heavy Menstrual Bleeding Due to Uterine Fibroids Taking Oral Oriahnn Capsules
Status: TERMINATED
Conditions: Heavy Menstrual Bleeding|Uterine Fibroids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Dose of i.v Oxycodone for Postoperative Pain After Laparoscopic Colorectal Surgery
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Oxycodone, 1.00 mg dose|DRUG: Oxycodone, 0.03 mg/kg dose|DRUG: Oxycodone, 0.02 mg/kg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects
Status: UNKNOWN
Conditions: Covid19|Povidone Iodine Adverse Reaction
Interventions: DRUG: Povidine iodine nasal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: vincristine|PROCEDURE: autologous hematopoietic stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BOL-DP-o-05 as an Add-On Treatment of Subjects With Newly Diagnosed Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: BOL-DP-o-05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Effect of SAR425899 on Energy Expenditure in Obese Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SAR425899|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Oral EC5026 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: EC5026 oral capsule|OTHER: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Multiple Oritavancin Doses on Safety, Tolerability, and Pharmacokinetics in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oritavancin|DRUG: Placebo (D5W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The U.S. Embryologist Fatigue Study
Status: COMPLETED
Conditions: Fatigue|Stress|Burnout, Professional|Musculoskeletal Pain|Back Pain|Neck Pain|Headache|Dizziness|Sleep Disturbance|Chest Pain|Syncope|Cardiovascular Diseases|Shortness of Breath|Gastrointestinal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patients With Vulvovaginal Candidiasis
Status: UNKNOWN
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: EPP-AF Gel 1%|DRUG: EPP-AF Gel 2%|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison Of Nerve Blocks In Cesarean Delivery
Status: COMPLETED
Conditions: Anesthesia, Obstetrical
Interventions: PROCEDURE: QLB|PROCEDURE: Intravenous patient controlled analgesia (PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability of Ringed Polytetrafluoroethylene Graft for Venous Vascular Reconstruction of Living Donor Liver Transplantation
Status: UNKNOWN
Conditions: Patency, Hepatic Venous Congestion
Interventions: PROCEDURE: MHV reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: HM95573, cobimetinib|DRUG: HM95573, cetuximab|DRUG: HM95573, cobimetinib|DRUG: HM95573, cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Different Exercise Methods in Adolescent Idiopathic Scoliosis
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Core Stabilization Exercises|OTHER: Schroth Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Fexofenadine HCl New Formulation Tablet
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Fexofenadine HCl Coated tablet|DRUG: Fexofenadine HCl New Formulation Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Enoxaparin Sodium Chemi and Clexane s.c.
Status: COMPLETED
Conditions: Enoxaparin Sodium is Administered to Healthy Volunteers
Interventions: DRUG: Enoxaparin Sodium|DRUG: Enoxaparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Life Style Intervention Manual in Pre Hypertensive Sedentary Population
Status: COMPLETED
Conditions: Pre Hypertension
Interventions: OTHER: Life Style Intervention Manual (With Exercise Under Supervision)|OTHER: General Advice|OTHER: Life Style Intervention Manual (Home Based)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: tacrolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Administrations of Propofol on Emergence Agitation in Preschool Children Undergoing Ambulatory Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia|Surgery
Interventions: DRUG: Propofol bolus|DRUG: Propofol continuous infusion|DRUG: Propofol bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Study of Penpulimab Combined With SOX in the Perioperative Treatment of Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: S-1,Oxaliplatin, Penpulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
Status: COMPLETED
Conditions: Intratracheal|Dexmedetomidine
Interventions: DRUG: Intratracheal dexmedetomidine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a New Combination Bronchodilator on Exercise in GOLD Stage II Moderate COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: LAMA/LABA|DRUG: LAMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Sibling Oocytes: ICSI vs. the PICSI Sperm Selection Method
Status: UNKNOWN
Conditions: Infertility
Interventions: DEVICE: ICSI petri dish|DEVICE: PICSI petri dish
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma
Status: TERMINATED
Conditions: Brain Cancer
Interventions: DRUG: Temozolomide|DRUG: Bevacizumab|DRUG: Lithium Carbonate|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Assessment of Intestinal Motility on Bowel Ultrasound in Patients With Inflammatory Bowel Disease: a Feasibility, Observational, Cross-sectional, Monocentric Study
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: PROCEDURE: non-interventional prospective cross-sectional observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Vildagliptin Versus Glibenclamide on Glycemia After Exercise in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Hypoglycemic Agents|Diabetic Blood Glucose Monitoring|Exercise
Interventions: DRUG: MET + Vildagliptin Group|DRUG: MET + Glibenclamide Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Elastic Bandage Compression on Pain and Function in Individuals With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Elastic bandage compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra Operative Continuous Laryngeal Nerve Monitoring During Thyroid Surgery and Interpretation of the Post-operative Voice Quality in Relation to the Electromyography Data Obtained During Surgery
Status: COMPLETED
Conditions: Thyroid Surgery
Interventions: PROCEDURE: Continuous nerve monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Sarilumab|DRUG: Sulfasalazine|DRUG: Leflunomide|DRUG: Bucillamine|DRUG: Tacrolimus|DRUG: Mizoribine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Flow Nasal Cannula and Standard Face Mask Oxygen Therapy in Children With Bronchiolitis
Status: COMPLETED
Conditions: Acute Bronchiolitis
Interventions: DEVICE: HFNCOT|OTHER: St-FMOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Spot Sign" Selection of Intracerebral Hemorrhage to Guide Hemostatic Therapy
Status: COMPLETED
Conditions: Stroke
Interventions: BIOLOGICAL: rfVIIa|OTHER: Standard saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Aspiration|Lung Abscess
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Sulbactam/Ampicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Foam Rolling on the Plantar Flexors' Properties
Status: COMPLETED
Conditions: Foam Roller|Achilles Tendon
Interventions: DEVICE: Foam rolling (shorter volume)|DEVICE: Foam rolling (longer volume)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Edge-to-edge Mitral Valve Repair in the Surgical Treatment for Hypertrophic Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: mitral valve repair by edge-to-edge technique|PROCEDURE: Septal myectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Two Versus Three Doses of Human Papillomavirus (HPV) Vaccine in India
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Cervical Precancerous Lesions
Interventions: BIOLOGICAL: Prophylactic quadrivalent HPV vaccine Merck (Gardasil®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Terminalia Chebula Fruit Extract on the Gut Microbiome and Skin Biophysical Properties
Status: COMPLETED
Conditions: Human Microbiome
Interventions: DIETARY_SUPPLEMENT: Terminalia Chebula fruit extract|DIETARY_SUPPLEMENT: Placebo|OTHER: Topical Terminalia Chebula|OTHER: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ligation of Anterior Internal Iliac Artery With Conservative Management of Partial or Focal Placenta Accreta Spectrum
Status: UNKNOWN
Conditions: Placenta Accreta
Interventions: PROCEDURE: Study group: lower segment resection with ligation of the anterior division of the internal iliac artery|PROCEDURE: Control group: lower segment resection without ligation of the anterior division of the internal iliac artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Secondary Foot Ulcers in Patients With Diabetes Using Systematic Measuring of Skin Temperature.
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic
Interventions: DEVICE: "Temp Touch" Diabetica Solutions inc.|OTHER: Inspection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Two-Part Study of BOTOX® Therapy for Ischemic Digits
Status: COMPLETED
Conditions: Raynaud's Disease
Interventions: DRUG: onabotulinum toxin type-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Darolutamide in Combination With Androgen-Deprivation Therapy in Prostate Cancer Patients With Lymph Node-positive After Radical Prostatectomy: A Prospective Observational Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide in addition to androgen deprivation therapy|DRUG: androgen deprivation therapy only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhalation Profiling of Idiopathic Pulmonary Fibrosis (IPF) Patients
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Assessment of Idiopathic Pulmonary Fibrosis over a period of up to 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clopidogrel High Dose Evaluation for the Patient With Coronary Artery Disease in Japan
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Clopidogrel|DRUG: Clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Posterior Canal Type of Benign Paroxysmal Positional Vertigo
Status: UNKNOWN
Conditions: Benign Paroxysmal Positional Vertigo (BPPV)
Interventions: PROCEDURE: Canalith repositioning maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]|DRUG: Supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures
Status: RECRUITING
Conditions: Proximal Femoral Fractures
Interventions: DRUG: Antibiotic loaded|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Double Cord Blood Transplant Study
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Acute|Leukemia, Myelocytic, Acute|Leukemia, Myeloid, Chronic|Lymphoma, Non-Hodgkin
Interventions: PROCEDURE: Expanded allogeneic cord blood (CB)|PROCEDURE: One Unmanipulated and One Expanded Cord Blood Unit|DRUG: Rituxan|DRUG: Melphalan|DRUG: Thiotepa|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mesna|RADIATION: Total body irradiation (TBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of the Transcatheter Tricuspid Valve Repair System (Trialign)
Status: UNKNOWN
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: Transcatheter tricuspid valve repair system (Trialign)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Use of Dermal Fat Graft as a Barrier Membrane
Status: COMPLETED
Conditions: Unilateral Cleft Lip
Interventions: PROCEDURE: Addition of dermal fat graft as protection over bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the PK Profile of Glepaglutide (ZP1848) After a Single IV and After Multiple SC Injections in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Glepaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Carboplatin/Paclitaxel With and Without Trastuzumab (Herceptin) in Uterine Serous Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: Carboplatin/Paclitaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multiple Dosing With BI 201335 on the Pharmacokinetics of Darunavir Co-administered With Ritonavir in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Darunavir|DRUG: Ritonavir|DRUG: BI 201335
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-arm, Open-label Clinical Study of SZ003 in the Treatment of Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: BIOLOGICAL: SZ003 CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy
Status: UNKNOWN
Conditions: Tonsillitis|Obstructive Sleep Apnea
Interventions: PROCEDURE: Cold Knife Tonsillectomy|PROCEDURE: Vessel Sealing System Tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Controlled Human Malaria Infection Model for Evaluation of Transmission-Blocking Interventions - Study 1
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine (low dose)|DRUG: Piperaquine (low dose)|DRUG: Sulfadoxine-pyrimethamine (high dose)|DRUG: Piperaquine (high dose)|BIOLOGICAL: malaria challenge infection, P. falciparum 3D7|DRUG: Atovaquone-proguanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Physical Therapy Program and Erector Spina Plane Block in Patients With Degenerative Lumbar Scoliosis
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: physical therapy|OTHER: physical therapy + espb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus Combination Chemotherapy in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: rituximab|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Under PIPAC
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis
Interventions: OTHER: Blood sample (20 ml) and EORTC QLQC30 survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Experimental Study to Evaluate the Impact of 18 Fluoro-PSMA (18F-PSMA) PET / CT in the Management of Patients With Prostate Cancer.
Status: UNKNOWN
Conditions: 18F-PSMA|Prostate Cancer
Interventions: DRUG: 18F-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate With Leucovorin Protection for Patients With Pneumocystis Carinii Pneumonia.
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimetrexate glucuronate|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valacyclovir to Prevent Vertical Transmission of Cytomegalovirus After Maternal Primary Infection During Pregnancy
Status: COMPLETED
Conditions: Congenital Cytomegalovirus Infection
Interventions: DRUG: Valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decrease Type II Diabetes in Gestational Diabetes Population
Status: UNKNOWN
Conditions: Gestational Diabetes|Diabetes Mellitus, Type 2|Breastfeeding|Diabetes Mellitus, Type 1|Impaired Glucose Tolerance
Interventions: BEHAVIORAL: Video clip|BEHAVIORAL: No video clip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Dasatinib in Children and Adolescents With Relapsed or Refractory Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Dasatinib|DRUG: Dasatinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effectiveness of PARO Companion Robot for Elderly With Mild Cognitive Impairment/Dementia in Elderly Residential Setting: A Quasi-experimental Study
Status: COMPLETED
Conditions: Technology
Interventions: DEVICE: Experimental group intervention|DEVICE: Control group intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AngongNiuhuang Pill for the Treatment of Patients With Acute Ischemic Stroke.
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DRUG: AngongNiuhuang pill|DRUG: Placebo of AngongNiuhuang pill|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-809|DRUG: VX-770|DRUG: VX-809 & VX-770|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castrate Resistant Prostate Cancer|BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2|RAD51B, RAD51C, RAD51D, or RAD54L Mutations
Interventions: DRUG: Carboplatin|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Er:YAG Laser and Air Polishing Application in Periodontal Treatment
Status: NOT_YET_RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: ERL + air polishing|PROCEDURE: ERL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
Status: UNKNOWN
Conditions: IUCD Complication
Interventions: DRUG: Isonicotinic Acid Hydrazide|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ROCKET II - Randomized Open Label Switch for Cholesterol Elevation on Kivexa + Kaletra Evaluation Trial
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: Truvada + Kaletra|DRUG: Kivexa + Kaletra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Powered Ported Bone Marrow Aspiration Procedures to Manual Standard Bone Marrow Aspiration Procedures Using Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Jamshidi Manual Standard Device|DEVICE: OnControl Powered Ported Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Check Point Inhibition After Autologous Stem Cell Transplantation in Patients at High Risk of Post Transplant Recurrence
Status: TERMINATED
Conditions: Multiple Myeloma|Lymphoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC
Status: COMPLETED
Conditions: Orthopedic Disorders
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influenza A/H1N1/2009-adjuvanted Vaccine in Renal Disease Patients
Status: COMPLETED
Conditions: Decreased Immunologic Activity [PE]|Influenza|Rejection
Interventions: BIOLOGICAL: Influenza A/H1N1 2009-AS03 adjuvanted (Pandemrix)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Value of Remote Ischemic Preconditioning
Status: COMPLETED
Conditions: Heart Diseases|Atrial Fibrillation
Interventions: PROCEDURE: RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Anatomic Results Between Bilateral and Conventional Abdominal Sacral Hysteropexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Bilateral Abdominal Sacral Hysteropexy|PROCEDURE: Conventional abdominal Sacral Hysteropexy|OTHER: Nulliparous women with no uterovaginal prolapsed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Nitric Oxide Injection Into Unresectable Solid Primary or Metastatic Tumors
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Nitric Oxide 25,000 ppm|DRUG: Nitric Oxide 50,000 ppm|DRUG: Nitric Oxide 100,000 ppm|DRUG: Nitric Oxide selected dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid Emulsions and Liver Function - Results After 5 Years.
Status: COMPLETED
Conditions: Liver Failure|Parenteral Nutrition-Related Hepatitis
Interventions: DRUG: Intravenous Lipid Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION