pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Karenitecin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Primary Peritoneal Carcinoma|Recurrent Ovarian Carcinoma
Interventions: DRUG: Cositecan|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Food on HR20033 and Pharmacokinetic After Multiple Dose in Healthy Volunteers
Status: UNKNOWN
Conditions: Type II Diabetes
Interventions: DRUG: FDC tablet|DRUG: FDC tablet|DRUG: FDC tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celebrex (Celecoxib) Treatment of Laryngeal Papilloma
Status: TERMINATED
Conditions: Laryngeal Papilloma
Interventions: DRUG: Celebrex|DEVICE: PDL|PROCEDURE: CO2 laser or microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT- LMA Supreme™ Versus the Spritztube® Tracheal Cannula in Anesthetized Adult Patients
Status: COMPLETED
Conditions: Airway Management
Interventions: DEVICE: Spritztube®|DEVICE: LMA Supreme™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Spondylitis, Ankylosing|Spondyloarthritis|Systemic Lupus Erythematosus|Sjogren's Syndrome|Systemic Sclerosis|Idiopathic Inflammatory Myopathies|Vasculitis, Systemic|Juvenile Idiopathic Arthritis|Dermatomyositis, Juvenile|Behçet Disease
Interventions: BIOLOGICAL: Recombinant Herpes Zoster Vaccine (RZV)|OTHER: MTX Discontinuation|OTHER: MMF Discontinuation|OTHER: Placebo|OTHER: MTX maintain|OTHER: MMF maintain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Continuous Safety and Efficacy of Litifilimab (BIIB059) in Adults With Active Systemic Lupus Erythematosus
Status: ENROLLING_BY_INVITATION
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Litifilimab|DRUG: Litifilimab-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Safety and Immunogenicity of 20vPnC in Infants in India and Taiwan
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine Patches Prior to Percutaneous Nerve Evaluation
Status: COMPLETED
Conditions: Overactive Bladder|Urge Incontinence|Fecal Incontinence
Interventions: DRUG: Lidocaine patch|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biofields Therapy on Warts
Status: COMPLETED
Conditions: Wart|Energy Medecine|Magnetism
Interventions: OTHER: True Biofield therapy|OTHER: Fake Biofield therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Withholding Feeds During Red Blood Cell Transfusion and TRAGI
Status: UNKNOWN
Conditions: Transfusion|Feeding During Transfusion|Transfusion Related Acute Gut Injury|Necrotising Enterocolitis
Interventions: OTHER: Withholding feeds|OTHER: feeding during transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Antithrombotic Therapy in Ischemic Stroke Patients With Non-Valvular Atrial Fibrillation and Atherothrombosis
Status: RECRUITING
Conditions: Ischemic Stroke|Atrial Fibrillation|Atherothrombosis
Interventions: DRUG: Oral Anticoagulant|DRUG: Antiplatelet Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Benefits and Tolerance of Exercise in Patients With Generalized and Stabilized Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: BEHAVIORAL: Physical exercise programme using a rowing machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing a Pilot Patient Navigator Program to Improve Access to Infertility Care for Underserved Patients
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: BEHAVIORAL: Infertility Patient Navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Validity and Reliability of the Upper Extremity Exercise Testing (UULEX) in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Upper extremity endurance test (UULEX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Vaccine Therapy and GM-CSF in Treating Patients With Progressive Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEST ABCs: Benefits and Effectiveness of Support Offered Through A Breastfeeding Clinic Study
Status: COMPLETED
Conditions: Exclusive Breastfeeding Rates|Neonatal Jaundice
Interventions: BEHAVIORAL: Breastfeeding Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treating Social Cognition With Theta Burst Stimulation: a Multicentric Study
Status: UNKNOWN
Conditions: Social Cognition in Patients With Schizophrenia
Interventions: DEVICE: Magstim® Active TBS|DEVICE: Magstim® Sham TBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Far Infrared Radiation on Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: long-sleeved white shirt impregnated with a long-infrared irradiation|DEVICE: long-sleeved white shirt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
Status: RECRUITING
Conditions: Acute Kidney Injury|Heart Failure|Contrast Induced Nephropathy|Coronary Angiography|Percutaneous Coronary Intervention
Interventions: DEVICE: Remote ischemic preconditioning|DEVICE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain
Status: UNKNOWN
Conditions: Post Operative Pain
Interventions: DRUG: a combination of PCA MO and continuous infusion of MO|DRUG: PCA MO only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Arthralgia of the Temporomandibular Joint. Pain Relief Following One Intra-articular Injection of Methylprednisolone
Status: COMPLETED
Conditions: Arthralgia|TMJ
Interventions: DRUG: Methylprednisolone|DRUG: Physiologic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Colon Carcinoma|Metastatic Colorectal Carcinoma|Metastatic Rectal Carcinoma|RAS Family Gene Mutation|Stage III Colon Cancer AJCC v7|Stage III Colorectal Cancer AJCC v7|Stage III Rectal Cancer AJCC v7|Stage IIIA Colon Cancer AJCC v7|Stage IIIA Colorectal Cancer AJCC v7|Stage IIIA Rectal Cancer AJCC v7|Stage IIIB Colon Cancer AJCC v7|Stage IIIB Colorectal Cancer AJCC v7|Stage IIIB Rectal Cancer AJCC v7|Stage IIIC Colon Cancer AJCC v7|Stage IIIC Colorectal Cancer AJCC v7|Stage IIIC Rectal Cancer AJCC v7|Stage IV Colon Cancer AJCC v7|Stage IV Colorectal Cancer AJCC v7|Stage IV Rectal Cancer AJCC v7|Stage IVA Colon Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVA Rectal Cancer AJCC v7|Stage IVB Colon Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7|Stage IVB Rectal Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Trametinib|DRUG: Trifluridine and Tipiracil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment of Recurrent HCC With Repeat Hepatectomy,and TACE With AFP Conversion
Status: COMPLETED
Conditions: Recurrent Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE|PROCEDURE: Hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Investigation of I2BS in PD
Status: RECRUITING
Conditions: Parkinson's|Parkinson Disease|Parkinson's Disease|Neurodegenerative Diseases|Neurodegeneration|Positron Emission Tomography
Interventions: OTHER: Positron Emission Tomography (PET) scan using BU99008 tracer|OTHER: FP-CIT Single-photon Emission Computed Tomography (SPECT) scan|OTHER: Magnetic Resonance Imaging (MRI) Scan|OTHER: Lumbar puncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics, and Bioavailability of IV and SC MABT5102A in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: MABT5102A|DRUG: MABT5102A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men
Status: COMPLETED
Conditions: Cortisol Resistance|Negative Feedback|ACTH|Mineralcorticoid|Glucocorticoid
Interventions: DRUG: Mifepristone|DRUG: Placebo|DRUG: Spironolactone|DRUG: Combined|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training and Plasma Lipoproteins in Man
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Hypertension|Myocardial Ischemia|Obesity
Interventions: BEHAVIORAL: diet, reducing|BEHAVIORAL: exercise|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Effect of a Low-Calorie Diet and/or Exercise Program on Risk Factors for Developing Breast Cancer in Overweight or Obese Postmenopausal Women
Status: COMPLETED
Conditions: Breast Cancer|Obesity|Weight Changes
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Alfapump System Versus Transjugular Intrahepatic Portosystemic Shunt and Paracentesis in the Treatment of Ascites
Status: TERMINATED
Conditions: Liver Cirrhosis
Interventions: DEVICE: Alfapump|DEVICE: TIPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depression Related Improvement With Vardenafil for Erectile Response
Status: COMPLETED
Conditions: Erectile Dysfunction|Depression
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Belimumab in SLE Patients
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Belimumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients
Status: TERMINATED
Conditions: Incontinence, Urinary and Urinary Bladder, Overactive|Overactive Bladder
Interventions: DRUG: GW679769
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ropinirole Hydrochloride in Progressive Myoclonic Epilepsy of Unverricht-Lundborg Type
Status: UNKNOWN
Conditions: Unverricht-Lundborg Syndrome
Interventions: DRUG: Ropinirole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DEVICE: Biolimus-eluting stent|DEVICE: Everolimus-eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Bacterial Microbiome of Endodontically Infected Primary and Permanent Teeth
Status: COMPLETED
Conditions: Endodontic Disease|Endodontic Inflammation
Interventions: DIAGNOSTIC_TEST: sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical and Radiographic Evaluation of Biodentine Versus Formocresol
Status: COMPLETED
Conditions: Pulp Disease, Dental
Interventions: OTHER: Biodentine|OTHER: Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: iQuit Mindfully: Text Messaging for Smoking Cessation
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Mindfulness-based Addiction Treatment|BEHAVIORAL: iQuit Mindfully|BEHAVIORAL: Self-Help guide|DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Primary Mediastinal Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Primary Mediastinal Large B-Cell Lymphoma
Interventions: DRUG: Copanlisib Hydrochloride|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia
Status: COMPLETED
Conditions: Familial Dysautonomia
Interventions: DRUG: Albuterol-sulphate|DRUG: Ipratropium-bromide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Flow Oxygen Therapy Following Tracheostomy
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: High Flow High Humidity device|DEVICE: Low Flow High Humidity device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Illusory Movements in Patients With Burns
Status: ACTIVE_NOT_RECRUITING
Conditions: Catabolic State|Burns|Illusions, Kinesthetic
Interventions: DEVICE: Functional Proprioceptive Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Gum Chewing on Polyethylene Glycol Related Intake Adherence, GI Side Effects and Bowel Preparation
Status: COMPLETED
Conditions: Colonoscopy
Interventions: OTHER: Chewing gums with PEG solution|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Detecting Occult HBV Infection in Liver Donors Positive for Antibody to Hepatitis B Core Antigen (Anti-HBc)
Status: UNKNOWN
Conditions: Occult Hepatitis B|Liver Transplant; Complications
Interventions: DRUG: entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving
Status: COMPLETED
Conditions: Driving|Intoxication|Impairment|Alcohol Impaired Driving
Interventions: DRUG: placebo|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis
Status: UNKNOWN
Conditions: Cataract|Uveitis
Interventions: DEVICE: Heparin Surface-Modified Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Therapy for Undergraduate College Students Who Binge Drink and Are Depressed
Status: COMPLETED
Conditions: Depression|Alcohol Abuse
Interventions: BEHAVIORAL: Combined Motivational Interviewing and Cognitive Behavioral Therapy|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BMN 110 for Morquio A Syndrome Patients Who Have Limited Ambulation
Status: TERMINATED
Conditions: Mucopolysaccharidosis IVA|Morquio A Syndrome|MPS IVA
Interventions: DRUG: BMN 110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: Anidulafungin, VER002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes
Status: RECRUITING
Conditions: Postoperative Infection|Lactate|Antibiotics
Interventions: DRUG: Preventive use of advanced antibiotics|OTHER: Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Hyperparathyroidism
Interventions: PROCEDURE: Parathyroid surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX
Interventions: RADIATION: Radiotherapy 50 Gy|DRUG: Fluorouracil/folic acid|DRUG: Chemotherapy in regimen with Oxaliplatin, fluorouracil, folinic acid (FOLFOX4)|RADIATION: Radiotherapy 50 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study With Single Ascending Doses of ODM-102
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ODM-102|DRUG: Placebo for ODM-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of MET on Meralgia Paraesthesia Postpartum "Muscle Energy Technique"
Status: COMPLETED
Conditions: Meralgia Paresthetica|Femoral Neuropathy
Interventions: OTHER: muscle energy technique|OTHER: conventional selected physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics of SHR-1707 in Alzheimer's Disease Patients.
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: SHR-1707|DRUG: SHR-1707 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over Trial
Status: COMPLETED
Conditions: Hyperuricemia|Gout|Kidney Calculi|Diabetes|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Treatment|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DS-5565 Phase III Study for Post-herpetic Neuralgia
Status: COMPLETED
Conditions: Post-Herpetic Neuralgia
Interventions: DRUG: Placebo|DRUG: DS-5565
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Individual Atazanavir and Cobicistat Compared With Atazanavir in Fixed-dose Combination With Cobicistat
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1 (HIV-1)
Interventions: DRUG: Atazanavir|DRUG: Cobicistat|DRUG: Atazanavir/Cobicistat FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: BRILLIANT-SC: A Study of the Efficacy and Safety of Blisibimod Administration in Subjects With IgA Nephropathy
Status: WITHDRAWN
Conditions: IgA Nephropathy
Interventions: DRUG: Blisibimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Systemic Bioavailability of Oral OTS167 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: OTS167IV|OTHER: Cherry syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808 30mg|DRUG: YH4808 50mg|DRUG: YH4808 100mg|DRUG: YH4808 200mg|DRUG: YH4808|DRUG: YH4808 100mg (repeat dose)|DRUG: YH4808 200mg (repeat dose)|DRUG: YH4808 600mg|DRUG: YH4808 800mg (single dose)|DRUG: YH4808 400 mg (repeat doses)|DRUG: Placebo|DRUG: Esomeprazole 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telehealth Exercise Platform to Reduce Frailty After Bone Marrow Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm
Interventions: OTHER: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/IIa Dose-escalation Clinical Study of VAC-3S
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: VAC-3S|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant 6 Cycles of Docetaxel and Cyclophosphamide or 3 Cycles of Cyclophosphamide/Epirubicin/Fluorouracil Followed by 3 Cycles of Docetaxel Versus 4 Cycles of Epirubicin and Cyclophosphamide Followed by Weekly Paclitaxel in Operable Breast Cancer (MASTER)
Status: COMPLETED
Conditions: Primary Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Cyclophosphamide|DRUG: Epirubicin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 334 20160172 Pediatric Migraine PK Study.
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: AMG 334 Dose 1|DRUG: AMG 334 Dose 2|DRUG: AMG 334 Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Project Step II: The Effects of Incentives and Feedback on Promoting Walking Within Overweight and Obese Adults
Status: COMPLETED
Conditions: Physical Activity|Sedentary Lifestyle|Overweight and Obesity
Interventions: BEHAVIORAL: Non-contingent incentives|BEHAVIORAL: Contingent incentives|BEHAVIORAL: Weekly feedback|BEHAVIORAL: Daily feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Combination of Durvalumab (MEDI4736) and Trabectedin in Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumor, Adult
Interventions: DRUG: Dose Escalation of Durvalumab and Trabectedin|DRUG: Dose Expansion of Durvalumab and Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Fixation Techniques for Displaced Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: PROCEDURE: Open Reduction and Internal Fixation|PROCEDURE: Non-Spanning External Fixation|PROCEDURE: Closed Reduction with Percutaneous Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet Delivered CBT for Body Dysmorphic Disorder
Status: COMPLETED
Conditions: Body Dysmorphic Disorder|BDD
Interventions: BEHAVIORAL: Cognitive behavior therapy|BEHAVIORAL: Supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Hydroxychloroquine|DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Ischemia
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: Mononuclear and mesenchymal stem cells|BIOLOGICAL: Mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia
Status: COMPLETED
Conditions: Depression|Anxiety|Mild Cognitive Impairment
Interventions: DRUG: Sertraline|DRUG: Venlafaxine|OTHER: CBT/Psychological Therapy|OTHER: Psychiatric Consultation|OTHER: Lifestyle Intervention Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of PERT for PEI in Unresectable Pancreatic Cancer.
Status: NOT_YET_RECRUITING
Conditions: Unresectable Pancreatic Cancer
Interventions: DRUG: creon 35.000 Ph.U (R)|OTHER: Best Standarard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of botulinumA Toxin (BotoxA) for Treatment of Neurogenic Bladder of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Neurogenic Bladder|Urinary Incontinence|Clostridium Botulinum Toxin Adverse Reaction
Interventions: DRUG: Cystoscopic injection of Botox into the urinary bladder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Orientation to Daily Occupational Performance and Conductive Education Approaches on Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome, Trisomy 21
Interventions: OTHER: CO-OP|OTHER: Conductive Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UARK 2003-25: A Study of Intravenous (IV) Busulfan (Busulfex®) in Multiple Myeloma Patients
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients
Status: TERMINATED
Conditions: Urinary Tract Infection
Interventions: DEVICE: Silver Alloy-Coated Urinary Catheters|DEVICE: Conventional Urinary Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser
Status: COMPLETED
Conditions: Hyperopia|Myopia|Astigmatism
Interventions: PROCEDURE: LASIK and PRK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Lebrikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Trial of Radiation Therapy in Oligometastatic mCRPC Prostate Cancer (ARTO)
Status: UNKNOWN
Conditions: Rate of PSA Response in Oligometastatic,CRPC Undergoing SBRT in Combination With Abiraterone Acetate (AA), Compared to Patients Treated With AA Alone
Interventions: RADIATION: SBRT - Ablative radiation Therapy|DRUG: Abiraterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cephalic Phase in Anorexia Nervosa,Bulimia Nervosa and Obese Binge Eaters
Status: UNKNOWN
Conditions: Anorexia Nervosa|Bulimia Nervosa
Interventions: PROCEDURE: chocolate cake
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BioFreedom FIM Clinical Trial.
Status: COMPLETED
Conditions: Treatment Of Stenotic Lesions In Native Coronary Arteries.
Interventions: DEVICE: Biofreedom Drug Eluting Stent|DEVICE: Biofreedom Drug Eluting Stent|DEVICE: Tuxus Liberte Drug Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Exercise in Older Cardiac Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: SystemCHANGE|BEHAVIORAL: CHANGE+|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation|COPD Exacerbation Acute
Interventions: DRUG: Titrated Oxygen|DRUG: Standard Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Botulin-A Toxin Instillations and Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder|Detrusor Instability|Detrusor Hyperreflexia
Interventions: DRUG: Botulinum-A toxin|DRUG: Dimethyl sulfoxide (DMSO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone
Status: UNKNOWN
Conditions: Chronic Nociceptive Pain|Neuropathic Pain|Non-cancer Pain
Interventions: DRUG: Oxymorphone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Sulfur Fecal Transplant for Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Fecal microbiota|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments
Status: COMPLETED
Conditions: Postmenopausal Flushing|Cardiovascular Risk Factor|Endothelial Dysfunction
Interventions: DRUG: Paroxetine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
Status: COMPLETED
Conditions: Chronic Low Back Pain|Sacroiliitis|Sacroiliac; Backache|Platelet Rich Plasma|Platelet|Injection Site|Ultrasound Therapy; Complications|Treatment
Interventions: DRUG: Platelet Rich Plasma Joint Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Changes After Stereotactic Radiotherapy for Early Stage NSCLC Cancer or Lung Metastasis
Status: TERMINATED
Conditions: Lung Cancer Stage I|Lung Cancer Stage II|Lung Metastases
Interventions: DIAGNOSTIC_TEST: Cardiac condition measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Epidemiological Screening of Psychiatric Disorders Among School Aged Children and Adolescent in Assiut Governorate
Status: UNKNOWN
Conditions: Child Behavior Disorders|Child Mental Disorder|Adolescent Behaviour
Interventions: BEHAVIORAL: 1. The Child Behavior Checklist (CBCL), parent form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Letrozole and Misoprostol for Early Pregnancy Loss Management
Status: RECRUITING
Conditions: Early Pregnancy Loss|Miscarriage in First Trimester|Miscarriage
Interventions: DRUG: Letrozole|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis
Status: COMPLETED
Conditions: Prurigo Nodularis|Nodularis Prurigo|Prurigo|Pruritus
Interventions: DRUG: nalbuphine HCl ER tablets 90 mg BID|DRUG: nalbuphine HCl ER tablets 180 mg BID|DRUG: Placebo tablets BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Portal Hypertension
Interventions: DRUG: Taurin 6g per day per oral for 28 days|PROCEDURE: HVPG Measurement baseline|PROCEDURE: HVPG Measurement day 28|DRUG: Placebo 6g per day per oral for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine as a Treatment for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence|Substance Abuse|Methamphetamine Abuse
Interventions: OTHER: Placebo|DRUG: Rivastigmine|DRUG: Rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of Plant-based or Animal-based Protein on Anthropocentric and Metabolic Parameters in Obese Subjects
Status: UNKNOWN
Conditions: Obesity, Abdominal|Glycation End Products, Advanced|Inflammation|Gut Microbiota
Interventions: OTHER: plant and animal protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Therapeutic Effect of the Extracorporeal Shock Wave Therapy on Shoulder Calcific Tendinitis
Status: UNKNOWN
Conditions: Calcific Tendinitis
Interventions: DEVICE: extracorporeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Artemether + Lumefantrine and Dihydroartemisinin + Piperaquine for Treating Malaria
Status: COMPLETED
Conditions: Malaria|Effectiveness
Interventions: DRUG: Dihydroartemisinin-piperaquine 160 mg/20 mg Oral Tablet|DRUG: Artemether-Lumefantrine 20 Mg-120 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Non-invasive Phrenic Nerve Stimulation on Weaning in Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Mechanical Ventilation|Weaning
Interventions: DEVICE: Non-invasive phrenic nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Immunogenicity Study of MT-2766 in Japanese Adults（COVID-19）
Status: TERMINATED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: MT-2766 High dose (3.75 µg)|DRUG: Placebo|BIOLOGICAL: MT-2766 Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuing Access to Axitinib (A406- AG- 013736 ) For Patients Previously Receiving AG 013736 In Clinical Trials
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: axitinib|DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Control and Physical Exercise
Status: TERMINATED
Conditions: Cognitive Function|Day-to-Day Function
Interventions: BEHAVIORAL: Space Fortress|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Stretching|BEHAVIORAL: Control Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: galyfilcon A|DEVICE: galyfilcon A plus|DEVICE: lotrafilcon A|DEVICE: polymacon|OTHER: spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Usefulness of Mic/Breakpoint Ratio and Penetration in Tissues. A Prospective Study of Clinical Validation
Status: WITHDRAWN
Conditions: Infection of Skin and/or Subcutaneous Tissue
Interventions: BEHAVIORAL: Implemented procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FHA: Characterization of Metabolic Status, Brain Circuitry, and Stress-Reactivity
Status: WITHDRAWN
Conditions: Anovulation|FHA|Eumenorrhea|Polycystic Ovary Syndrome
Interventions: PROCEDURE: Screening evaluation|PROCEDURE: Meal Response|GENETIC: Blood Collection|PROCEDURE: Functional MRI|PROCEDURE: Endocrine Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Estimating EC95 of Remifentanil for Cough Prevention During Emergence From Total Intravenous Anesthesia With Propofol and Remifentanil in Patients Undergoing Transsphenoidal Hypophysectomy
Status: COMPLETED
Conditions: Hypophysectomy
Interventions: DRUG: Administration of remifentanil with TCI system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)
Status: COMPLETED
Conditions: Acute Episode of Overt Hepatic Encephalopathy|Hepatic Encephalopathy
Interventions: DRUG: ornithine phenylacetate|DRUG: placebo intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilization by Plerixafor of Haematopoietic Stem Cells in Children
Status: COMPLETED
Conditions: Children Cancer, Solid Tumor
Interventions: DRUG: Plerixafor, mozobil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rolled Pericardium Versus Cryopreserved Allograft to Treat Native or Prosthetic Aortic Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Infections and Inflammations
Interventions: PROCEDURE: Explantation of a previous aortic graft or endograft and reconstruction by arterial allograft or rolled pericardium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibody Persistence, and Safety and Tolerability of a Booster Dose of the Meningococcal B Vaccine After the Completion of the Vaccination Course in Study V72_28
Status: COMPLETED
Conditions: Meningoccocal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Bexsero® vaccine (1 dose at study month zero)|BIOLOGICAL: Bexsero® vaccine (2 doses 1 month apart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Valerian on Insomnia in Menopausal Women
Status: RECRUITING
Conditions: Menopausal Women|Insomnia
Interventions: DRUG: Valerian
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remazolam on Anesthesia Recovery in Patients Undergoing Fundus Surgery
Status: NOT_YET_RECRUITING
Conditions: Remazolam Anesthesia|Postoperative Recovery
Interventions: DRUG: ciprofol|DRUG: Remazolam|DRUG: Flumazenil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Prospective Cohort Study to Describe the Clinical Characteristics of COVID-19, the Acquired Immune Response and the Biological and Clinical Parameters of Patients Followed in Oncology by the Saint-Joseph Hospital Group for a Period of 6 Months During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Oncology|COVID-19
Interventions: OTHER: Obvio-19 app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Implementing Personalized Exercise Prescriptions Through Mobile Health in the Elderly Cancer Survivors
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Personalized Smartwatch|BEHAVIORAL: Facebook Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE