pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
Status: COMPLETED
Conditions: Influenza|Viral Respiratory Infection|Acute Viral Upper Respiratory Infections
Interventions: DRUG: XC221 100 mg|DRUG: XC221 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stress and Ischemic Heart Disease. The Effect of Bio Feedback Guided Stress Management on Life Quality Including Signs of Depression and Stress
Status: COMPLETED
Conditions: Biofeed Back Guided Stress Management|Ischemic Heart Disease
Interventions: BEHAVIORAL: pressure pain sensitivity measure followed bu acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Bendamustine in Patients With Relapsed or Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Adult Lymphocyte Depletion Hodgkin Lymphoma|Adult Lymphocyte Predominant Hodgkin Lymphoma|Adult Mixed Cellularity Hodgkin Lymphoma|Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma|Adult Nodular Sclerosis Hodgkin Lymphoma|Recurrent Adult Hodgkin Lymphoma
Interventions: DRUG: gemcitabine hydrochloride|DRUG: bendamustine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Carboplatin and Etoposide or Temozolomide and Capecitabine in Treating Patients With Neuroendocrine Carcinoma of the Gastrointestinal Tract or Pancreas That Is Metastatic or Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Neuroendocrine Carcinoma|Intestinal Neuroendocrine Carcinoma|Pancreatic Neuroendocrine Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Session of 30-Minute Mindful Breathing in Reducing Fatigue
Status: COMPLETED
Conditions: Fatigue|Hematologic Malignancy
Interventions: OTHER: 30-minute mindful breathing|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Constraint Induced Movement Therapy and Proprioceptive Neuromuscular Facilitation on Lower Limb Motor Function
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Constrained induced movement|OTHER: Proprioceptive Neuromuscular facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Dose of Antiangiogenic Multitargeted DOVITINIB (TKI258) Plus Paclitaxel in Patients With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Dovitinib|DRUG: Dovitinib + Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate Students
Status: UNKNOWN
Conditions: Stress, Psychological|Anxiety Disorders|Depression, Unipolar
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate in Treating Patients With Chronic Neutrophilic Leukemia or Atypical Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Chronic Neutrophilic Leukemia
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Fixed-dose Combination of Naratriptan and Naproxen in Acute Treatment of Migraine
Status: WITHDRAWN
Conditions: Migraine|Headache
Interventions: DRUG: Fixed-dose combination of naratriptan+naproxen|DRUG: Naratriptan|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Acute Pain Dynamics
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transition Model-Based Discharge Training in Parents of Preterm Infants
Status: COMPLETED
Conditions: Preterm Infant|Parents|Premature Birth|Randomized Controlled Trial|Transitional Care
Interventions: DEVICE: TRAMPRE|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of an mHealth Intervention on Physical Activity and Nutrition: the FutureMe Trial
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: FutureMe App|BEHAVIORAL: Conventional TrackingApp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of I Quit Ordinary Smoking on the Arterial Wall and Endothelial Glycocalyx Properties of Smokers
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: DEVICE: I quit ordinary smoking (IQOS)|OTHER: Conventional cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: PD-1 antibody|DRUG: Capecitabine|DRUG: Irinotecan|RADIATION: Neoadjuvant Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Upper Airway Collapsibility|Upper Airway Obstruction
Interventions: PROCEDURE: elevated body position|PROCEDURE: supine body position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Quercetin Supplementation on Endometriosis Outcomes
Status: RECRUITING
Conditions: Endometriosis
Interventions: DIETARY_SUPPLEMENT: Quercetin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Compare Effects Of GSK189075 In Combination With Either Furosemide Or Hydrochlorothiazide
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Hydrochlorothiazide (HCTZ)|DRUG: Remogliflozin etabonate (GSK189075)|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Tolerability of GBT440 Administered to Subjects With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Hypoxemia
Interventions: DRUG: GBT440|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
Status: TERMINATED
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Neurotoxicity|Ovarian Cancer|Primary Peritoneal Cavity Cancer|Sarcoma
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perindopril and Telmisartan for the Treatment of Nonalcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: DRUG: Perindopril|DRUG: Telmisartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Bioequivalence of 30 and 120 mg Nifurtimox Tablets in Chronic Chagas' Patients
Status: COMPLETED
Conditions: Chagas Disease
Interventions: DRUG: Nifurtimox (BAYa2502) (4 x 30 mg tablet)|DRUG: Nifurtimox (BAYa2502) (slurry of 4 x 30 mg tablets in tap water)|DRUG: Nifurtimox (BAYa2502) (120 mg tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy
Status: RECRUITING
Conditions: Bladder Cancer|Urinary Bladder Neoplasm|Urologic Neoplasms|Neoplasms|Urinary Bladder Diseases
Interventions: PROCEDURE: Fiducial marker placement|DIAGNOSTIC_TEST: Multiparametric MRI (mpMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for Assessment of the Efficacy and Safety of Mirtazapine (Smilon) in Depression Patients With Pain
Status: COMPLETED
Conditions: Depression|Pain
Interventions: DRUG: Smilon®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia
Status: SUSPENDED
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Etoposide Phosphate|DRUG: Mitoxantrone Hydrochloride|DRUG: Peposertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults
Status: RECRUITING
Conditions: Cognitive Decline|Nutrition, Healthy|Brain Injuries
Interventions: DIETARY_SUPPLEMENT: Blueberry powder|OTHER: Controlled and matched powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of BI 207127 in Combination With Faldaprevir and Ribavirin for Treatment of Patients With Hepatitis C Infection, Including Patients Who Are Not Eligible to Receive Peginterferon: HCVerso2
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI 207127-placebo: 8-week treatment|DRUG: Ribavirin: 24-week treatment|DRUG: BI 207127: 24-week treatment|DRUG: Faldaprevir: 24-week treatment|DRUG: Faldaprevir: 24-week treatment|DRUG: Ribavirin-placebo: 8-week treatment|DRUG: BI 207127: 24-week treatment|DRUG: Faldaprevir-placebo: 8-week treatment|DRUG: Faldaprevir: 16-week treatment|DRUG: Ribavirin: 16-week treatment|DRUG: RBV: 24-week treatment|DRUG: BI 207127: 16-week treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Calcification|Metabolic Syndrome|Dyslipidemias
Interventions: DRUG: Guideline directed statin therapy|DRUG: High intensity statin plus ezetimibe therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity Changes in Irritable Bowel Syndrome (IBS), Anxiety, and Depression Following the Use of Viome Precision Nutrition Program (VPNP)
Status: COMPLETED
Conditions: Depression, Anxiety|IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: VIOME Precision Nutrition Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Role of Inflammatory and Structural Ultrasound Abnormalities by Explaining the Perspective of Patients With Psoriatic Arthritis
Status: UNKNOWN
Conditions: Psoriatic Arthritis
Interventions: OTHER: General evaluation|OTHER: Dermatological evaluation|OTHER: Rheumatological evaluation|OTHER: para clinical data|OTHER: Patient reported outcomes (PROs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Imaging Non-motor Symptoms of Parkinson's Disease by Novel 18F-DTBZ and Florbetapir F-18 PET
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: 18F- DTBZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immediate Implant With no Graft , Autogenous Graft or Xenograft.
Status: UNKNOWN
Conditions: Dental Diseases
Interventions: PROCEDURE: control group|PROCEDURE: study group|PROCEDURE: study group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hyperventilation Versus Exercise Testing Sensitivity in Exercise Induced Asthma
Status: UNKNOWN
Conditions: Exercise Induced Bronchospasm
Interventions: DIAGNOSTIC_TEST: Eucapnic voluntary hyperventilation|DIAGNOSTIC_TEST: Exercise challenge on a cycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Topical Phenylephrine 2.5% on EVP in Normal Human Eyes
Status: COMPLETED
Conditions: Assess Phenylephrine on EVP and IOP
Interventions: DRUG: Phenylephrine 2.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A PROSPECTIVE, MULTICENTER, SINGLE-ARM TRIAL FOR THE NEW SIZES OF BRIDGE STENTS FOR VERTEBRAL ARTERY STENOSIS: Bridge-MAX
Status: RECRUITING
Conditions: Brain Diseases|Vertebral Artery Thrombosis|Vertebral Artery Stenosis
Interventions: DEVICE: Bridge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Limb-Girdle Muscular Dystrophy
Status: COMPLETED
Conditions: Becker Muscular Dystrophy|Limb-Girdle Muscular Dystrophy, Type 2A (Calpain-3 Deficiency)|Limb-Girdle Muscular Dystrophy, Type 2B (Miyoshi Myopathy, Dysferlin Deficiency)|Limb-Girdle Muscular Dystrophy, Type 2I (FKRP-deficiency)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of LY2409021 in Participants With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY2409021|DRUG: Placebo|DRUG: Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Impact of the Patient Activated Learning System (PALS) on Knowledge Acquisition, Recall, and Decision Making
Status: COMPLETED
Conditions: Patient Education
Interventions: OTHER: PALS|OTHER: WebMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: propofol|DRUG: Etomidate|DRUG: Propofol and Etomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Mechanisms for Atrial Fibrillation in Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Atrial Fibrillation|Obstructive Sleep Apnea|Hypertension|Autonomic Dysfunction|Arterial Stiffness
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: XW003 injection|DRUG: Metformin|DRUG: Warfarin|DRUG: Rosuvastatin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials of CT-guided Percutaneous Irreversible Electroporation（IRE）in the Treatment of Patients With Locally Advanced Tumors
Status: UNKNOWN
Conditions: Neoplasms|Carcinoma
Interventions: PROCEDURE: CT-guided percutaneous irreversible electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Accuracy of the Vessel Navigator Tool for Catheterization of Supra-aortic Vessels - ARCHIBALD
Status: COMPLETED
Conditions: Vascular Diseases|Cerebrovascular Diseases|Cardiovascular Diseases|Aortic Aneurysm|Arteriovenous Malformation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CYT003-QbG10 for Treatment of Allergic Asthma Bronchial
Status: COMPLETED
Conditions: Allergic Bronchial Asthma
Interventions: DRUG: CYT003-QbG10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trabectedin and Irinotecan for Refractory Pediatric Sarcomas
Status: UNKNOWN
Conditions: Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma|Recurrent Rhabdomyosarcoma
Interventions: DRUG: Combined chemotherapy with trabectedin followed by irinotecan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of a Self-Management + Peer Mentoring Intervention for Adolescent and Young Adult Childhood Cancer Survivors
Status: COMPLETED
Conditions: Childhood Cancer Survivors
Interventions: BEHAVIORAL: Managing Your Health: Self-Management + Peer Mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection|Pregnancy|Postpartum
Interventions: DRUG: CAB LA 600mg|DRUG: RPV LA 900mg|DRUG: CAB LA 400mg|DRUG: RPV LA 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate (ZS) 10g|DRUG: Sodium Zirconium Cyclosilicate (ZS) 5g|DRUG: Sodium Zirconium Cyclosilicate (ZS) 10g|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Sequential Compression Devices and Foot Pumps in the Obstetric Population
Status: TERMINATED
Conditions: Thrombophilia
Interventions: DEVICE: Kendall A-V foot impulse pump, model 6060|DEVICE: Kendall sequential compression device, model 9525
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tumoral Bone Strength Assessment by Numerical Simulation Using Quantitative CT : the MEKANOS Study
Status: RECRUITING
Conditions: Metastases to Bone|Metastatic Breast Cancer|Metastatic NSCLC
Interventions: OTHER: Evaluation of the fracture risk using data from routine qCT (quantitative Computed Tomography) scan and numerical simulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CGRP's Cluster Headache Inducing Abilities in Cluster Headache Patients
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: Calcitonin-Gene Related Peptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PMCF Study Protocol for PROFEMUR® Gladiator Plasma Femoral Stems and PROCOTYL® L Beaded Acetabular Components
Status: ACTIVE_NOT_RECRUITING
Conditions: Joint Disease
Interventions: DEVICE: PROFEMUR® Gladiator Plasma Femoral Stems
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Scalp Nerve Block With Ropivacaine on Postoperative Recovery Quality
Status: COMPLETED
Conditions: Meningioma
Interventions: PROCEDURE: ropivacaine|PROCEDURE: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiovascular Risk Screening and Risk Reduction in Women Vets
Status: COMPLETED
Conditions: Cardiovascular Diseases|Hypertension|Hyperlipidemias|Dyslipidemias|Obesity|Diabetes Mellitus|Tobacco Use Disorder|Overweight
Interventions: BEHAVIORAL: CV Toolkit Components
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Geriatric Assessment in Predicting Chemotherapy Toxicity and Vulnerabilities in Older Patients With Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Neoplasm
Interventions: OTHER: Comprehensive Geriatric Assessment|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Developing a Physiological Understanding of High Duration Activity
Status: ACTIVE_NOT_RECRUITING
Conditions: Sedentary Lifestyle|Hyperinsulinemia|Glucose Tolerance Impaired|Low-density-lipoprotein-type|Aging Problems|Lipid Metabolism Disorders|Inactivity, Physical|Metabolic Disorder, Glucose
Interventions: BEHAVIORAL: Muscular Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nicotine Vaccination and Nicotinic Receptor Occupancy
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BIOLOGICAL: NicVAX|RADIATION: [123I]5-IA-85380|DRUG: Nicotine bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of rhASB in Patients With Mucopolysaccharidosis VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis VI
Interventions: DRUG: N-acetylgalactosamine 4-sulfatase|DRUG: Placebo/rhASB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ginsana in Improving Half-time Hemoglobin Re-oxygenation in Healthy Recreational Sports People
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ginsana|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of 3 Orthodontic Fixed Retention Schemes on Post-treatment Stability and Gingival Recession
Status: RECRUITING
Conditions: Relapse|Orthodontic Retention
Interventions: DEVICE: Experimental: Single strand β-Ti fixed retainer|DEVICE: Experimental: SS fixed retainer|DEVICE: Experimental: Twisted fixed retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intramyometrial Injection of Terlipressin Versus Carbitocin on Hemoglobin and Blood Loss During Open Myomectomy Operations Without Using Haemostatic Tourniquets
Status: RECRUITING
Conditions: Myoma
Interventions: DRUG: Terlipressin|DRUG: Carbetocin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Patupilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Insulin for Posttraumatic Stress Disorder
Status: RECRUITING
Conditions: PTSD
Interventions: DRUG: Intranasal insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth Integrated Model of Hypertension, Diabetes and Antenatal Care in India and Nepal
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus (GDM)|Pregnancy Induced Hypertension (PIH)|Anemia
Interventions: OTHER: mHealth Integrated Model of Antenatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Study of Liquid and Lyophilized Formulations of Subcutaneous Tetrodotoxin (TTX) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tetrodotoxin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Bevacizumab Versus DEX Implant Followed by Bevacizumab in ME Secondary to BRVO
Status: UNKNOWN
Conditions: Branch Retinal Vein Occlusion With Macular Edema
Interventions: DRUG: Intravitreal bevacizumab and dexamethasone implant Injection|DEVICE: Intravitreal dexamethasone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium Over Postprandial Effects of Fatty Meal on Metabolism, Blood Pressure, Oxidative Stress, Endothelial Function.
Status: UNKNOWN
Conditions: Obesity
Interventions: OTHER: Dietary calcium|DIETARY_SUPPLEMENT: Supplementary calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Pentoxifylline and Lumbar Radiculopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Radiculopathy|Lumbar Disc Herniation|Lumbar Disc Disease
Interventions: DRUG: Pentoxifylline Oral Tablet|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-8353 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Malignancies (MK-8353-013)
Status: COMPLETED
Conditions: Neoplasms|Colorectal Cancer
Interventions: DRUG: MK-8353|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Behavioural Therapy (MIBT) Versus Psychodynamic Therapy for Patients With Major Depressive Disorder in Psychotherapeutic Day Treatment. A Randomised Clinical Pilot Trial
Status: UNKNOWN
Conditions: Major Depressive Disorder|Personality Disorder
Interventions: BEHAVIORAL: Mindfulness-based Behavioural Therapy (MIBT)|BEHAVIORAL: PT (psychodynamic therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International Randomized Study of the TransMedics Organ Care System (OCS Lung) for Lung Preservation and Transplantation
Status: COMPLETED
Conditions: Lung Preservation
Interventions: DEVICE: OCS Lung|DEVICE: Cold flush and storage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy
Status: UNKNOWN
Conditions: Inguinal Hernia|Laparoscopic Surgery|Pain|Sexual Dysfunction, Physiological
Interventions: PROCEDURE: Laparoscopic totally extraperitoneal inguinal hernia repair|PROCEDURE: Open tension free inguinal hernia mesh repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Airtime Incentives to Improve Short Message Service Surveys in Colombia and Tanzania
Status: COMPLETED
Conditions: Surveys and Questionnaires|Noncommunicable Diseases
Interventions: OTHER: 1X airtime incentive|OTHER: 2X airtime Incentive|OTHER: Lottery airtime incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sintilimab and Bevacizumab Combined With Radiotherapy for Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab and Bevacizumab Combined with Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of IBI356 in Healthy Participants and in Atopic Dermatitis Patients
Status: RECRUITING
Conditions: Healthy Participants|Atopic Dermatitis Patients
Interventions: DRUG: IBI356 for MAD|DRUG: Dupilumab for MAD|DRUG: IBI356 for SAD|DRUG: Placebo for SAD|DRUG: Placebo for MAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of "Prodovite®" In Athletic Performance
Status: UNKNOWN
Conditions: SPORTS NUTRITION
Interventions: DIETARY_SUPPLEMENT: "Prodovite®" VMP35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MDR - Longevity IT Oblique and Offset Liners
Status: ENROLLING_BY_INVITATION
Conditions: Non-inflammatory Degenerative Joint Disease (NIDJD)|Avascular Necrosis|Protrusio Acetabuli|Traumatic Arthritis|Slipped Capital Femoral Epiphyses|Fracture of the Pelvis|Diastrophic Variant|Osteoarthritis|Fused Hip
Interventions: DEVICE: Total Hip Arthroplasty with Longevity IT Oblique Liners|DEVICE: Total Hip Arthroplasty with Longevity IT Offset Liners
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the RevLite Laser System for the Treatment of Refractory Mixed Type Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DEVICE: Revlite Laser System with hydroquinone skin care regimen|OTHER: Hydroquinone skin care regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Analysis of COMPASsion and Humanisation of Adolescents Facing the End-of-life Processes.
Status: NOT_YET_RECRUITING
Conditions: Compassion|Death Anxiety|Adolescent Behavior
Interventions: OTHER: questionnaire|OTHER: Discussion group|OTHER: Reflective diary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Intensive BP treatment group|DRUG: Standard BP treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Glycerol Phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Continuous Positive Airway Pressure Therapy in IPF
Status: RECRUITING
Conditions: Interstitial Lung Disease|Obstructive Sleep Apnea
Interventions: DEVICE: Auto-CPAP|OTHER: Withdrawal of Auto-CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Immediate Versus Delayed Initiation of Oral Contraceptive Pills After Abortion
Status: COMPLETED
Conditions: Abortion
Interventions: BEHAVIORAL: Immediate initiation of OCPs|BEHAVIORAL: Delayed initiation of OCPs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Cedirogant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia|Chronic Lymphocytic Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome
Interventions: DEVICE: Miltenyi reagent system|DRUG: Fludarabine|DRUG: Cyclosporine|DRUG: Cyclophosphamide|OTHER: FILGRASTIM (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract Carcinoma
Status: COMPLETED
Conditions: Advanced Biliary Tract Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: MEK162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGF and PRF in the Gingival Recessions Treatment
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Concentrated Growth Factor Membrane|PROCEDURE: Platelet Rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Behavioural Therapy and Physical Therapy for Provoked Vestibulodynia
Status: COMPLETED
Conditions: Vulvar Vestibulitis
Interventions: BEHAVIORAL: cognitive-behavioural therapy|BEHAVIORAL: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: Root coverage with collagen matrix graft|PROCEDURE: Root coverage with subepithelial connective tissue graft|OTHER: Basic periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Quality of Life of Patients Suffering From OTOTOXICITY Due to Chemotherapy Based on Platinum Salts Fitted With a Hearing Aid Compared to Those Not Fitted.
Status: RECRUITING
Conditions: Cancer|Ototoxicity, Drug-Induced|Quality of Life|Hearing Disorders
Interventions: OTHER: Patients suffering from chemotherapy-induced ototoxicity|OTHER: Patients suffring from chemotherapy-induced ototoxicity wearing hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Validation Cohort Study of a Prediction System on nSLN Metastasis in Early Breast Cancer
Status: UNKNOWN
Conditions: Lymph Node Metastases|Breast Cancer|Predictive Cancer Model
Interventions: PROCEDURE: axillary lymph node dissection (ALND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Firehawk™ Coronary Stent System in the Treatment of Coronary Chronic Total Occlusion Lesion(s)
Status: UNKNOWN
Conditions: Drug-Eluting Stents|Percutaneous Coronary Intervention|Tomography, Optical Coherence
Interventions: DEVICE: Firehawk sirolimus target eluting coronary stent system|DEVICE: XIENCE Everolimus-Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia
Status: COMPLETED
Conditions: Pre-Eclampsia|Fetal Growth Retardation|Premature Birth|Placental Insufficiency
Interventions: DRUG: Acetylsalicylic Acid 160 mg|DRUG: Acetylsalicylic Acid 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Weight Management Programs on Cardiometabolic Risk Profile in Overweight Women
Status: COMPLETED
Conditions: Overweight and Obesity|Dyslipoproteinemia
Interventions: DIETARY_SUPPLEMENT: Meal replacement (MR)|OTHER: Control (C)|DIETARY_SUPPLEMENT: Verum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Arabinoxylan-Oligosaccharides Compared to Other Prebiotics in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: FOS-IN|DIETARY_SUPPLEMENT: AXOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Daily Inclusion of Eggs in a Heart-Healthful Dietary Pattern in Hyperlipidemic Adults
Status: RECRUITING
Conditions: Hyperlipidemias
Interventions: OTHER: DASH eating plan with eggs|OTHER: DASH eating plan without eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
Status: COMPLETED
Conditions: Psychotic Disorders
Interventions: DRUG: Aripiprazole or Perphenazine|DRUG: Metformin|DRUG: Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Calcium And Vitamin D In Nutritional Rickets And It's Management
Status: COMPLETED
Conditions: Nutritional Rickets
Interventions: DRUG: Vitamin D|DRUG: Calcium Carbonate|DRUG: Vitamin D and Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 5-azacitidine in Combination With Vorinostat in Patients With Relapsed or Refractory Diffuse Large b Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: azacytidine|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP
Status: RECRUITING
Conditions: Hiv|Opioid Use Disorder
Interventions: BEHAVIORAL: community-friendly health recovery program|DRUG: Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Proof of Concept Study to Evaluate the Effectiveness of Ustekinumab in Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Hypnosis in Total Knee Arthroplasty Under Spinal Anesthesia
Status: COMPLETED
Conditions: Arthroplasty Complications|Knee Osteoarthritis|Anesthesia Complication|Hypnotic; Anxiety Disorder|Sedation Complication
Interventions: DEVICE: VRH|DRUG: Midazolam sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Tibiofemoral Rotational Alignment After Mobile and Fixed Bearing Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: total knee arthroplasty|DEVICE: total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Cryotherapy to Prevent Paclitaxel-induced Peripheral Neuropathy and Nail Changes in Women With Breast Cancer
Status: TERMINATED
Conditions: Cryotherapy Effect|Peripheral Neuropathy|Nail Toxicity
Interventions: OTHER: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clofarabine and Cytarabine in Treating Patients With Acute Myeloid Leukemia With Minimal Residual Disease
Status: TERMINATED
Conditions: Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: clofarabine|DRUG: cytarabine|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gelofusine on GLP1-receptor Imaging
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent|Diabetes Mellitus
Interventions: DRUG: Gelofusine|RADIATION: 111In-exendin 4 SPECT/CT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adults
Interventions: BIOLOGICAL: Clinical Center Reference Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Esketamine and Butorphanol for Post-Lobectomy Pain
Status: COMPLETED
Conditions: Esketamine|Pain|Post-thoracotomy Pain Syndrome|Thoracic Diseases
Interventions: DRUG: Esketamine|DRUG: Butorphanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bi-Ventricular Pacing in Patients With Atrial Fibrillation and Heart Failure (BIFF-Study)
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DEVICE: InSync III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Intensity Interval Training Verses Aerobic Exercises on Emotional Intelligence of University Students
Status: UNKNOWN
Conditions: High Intensity Interval Training|Aerobic Exercise
Interventions: DIAGNOSTIC_TEST: self-report Emotional Intelligence test (SSCEIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Caregiver Led Strategies to Malnutrition and Care-giving Among Children With Cerebral Palsy
Status: COMPLETED
Conditions: Weight Gain
Interventions: BEHAVIORAL: positive deviance hearth strategy|BEHAVIORAL: Parent facilitator trainings|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma in the Soft Tissue|Prostate Carcinoma Metastatic in the Bone|Stage IV Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Abiraterone Acetate|DRUG: Antiandrogen Therapy|DRUG: Cabazitaxel|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Orchiectomy|OTHER: Pharmacological Study|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrinogen Early In Severe Trauma StudY II
Status: RECRUITING
Conditions: Trauma|Haemorrhagic Shock|Coagulopathy
Interventions: DRUG: Fibrinogen Concentrate|OTHER: Cryoprecipitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT