pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Standard Implants With Bone Regeneration vs Short Implants
Status: UNKNOWN
Conditions: Implant Complication|Bone Resorption
Interventions: PROCEDURE: Short implant placement|PROCEDURE: Bone regeneration with longer implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Deep Transcranial Magnetic Stimulation in Patients With Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation with double-cone coil|DEVICE: Transcranial Magnetic Stimulation with sham coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: TP-271
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Modified Percutaneous Achilles Tendon Lengthening by Triple Hemisection for Achilles Tendon Contracture
Status: UNKNOWN
Conditions: Achilles Tendon Contracture
Interventions: PROCEDURE: Achilles tendon lengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early EUS in Acute Biliary Pancreatitis
Status: COMPLETED
Conditions: Acute Biliary Pancreatitis
Interventions: PROCEDURE: Endoscopic Ultrasound|DEVICE: Olympus 180 series echoendoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect on Kidney Function Recovery Guiding Decongestion With VExUS in Patients With Cardiorenal Syndrome 1
Status: COMPLETED
Conditions: Cardiorenal Syndrome|Acute Kidney Injury|Decompensated Heart Failure|Fluid Overload|Ultrasound Therapy; Complications
Interventions: DIAGNOSTIC_TEST: Vexus|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Time Restricted Feeding (TRF) in Improving the Health of Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Weight Loss|Metabolic Syndrome|Overweight and Obesity
Interventions: BEHAVIORAL: Time Restricted Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multiple-ascending-dose Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of MEDI0382 in Overweight and Obese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MEDI0382|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China
Status: NOT_YET_RECRUITING
Conditions: Pharmacokinetics
Interventions: DRUG: ZX-7101A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms, and Higher Risk Myelodysplastic Syndrome - The Biology and Outcome (BiO)-Project
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Higher Risk Myelodysplastic Syndromes (MDS With Excess Blasts 2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Ozanimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusions of Mesenchymal Stromal Cells in Children With Multisystem Inflammatory Syndrome
Status: WITHDRAWN
Conditions: Multisystem Inflammatory Syndrome in Children
Interventions: BIOLOGICAL: Human Cord Tissue Mesenchymal Stromal Cells (hCT-MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Client-centered Intervention Aiming to Improve Functioning in Daily Life After Stroke
Status: COMPLETED
Conditions: Stroke|Physical Disability|Multiple Disability
Interventions: BEHAVIORAL: Client-centered ADL intervention|BEHAVIORAL: Usual ADL intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Long-term Persistence of Hepatitis A Antibodies in Healthy Adults Who Were Vaccinated 21-25 Years Earlier With GlaxoSmithKline (GSK) Biologicals' Hepatitis A Vaccine, Havrix®
Status: WITHDRAWN
Conditions: Hepatitis A
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Physical Activity and Sedentary Behavior During Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Pregnant Woman
Interventions: BEHAVIORAL: In person PA sessions|BEHAVIORAL: Interactive videoconference PA sessions|BEHAVIORAL: In person and by videoconference (mixed format) PA sessions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate the Efficacy and Safety of Pletaal (Cilostazol) in Subjects With Vasospastic Angina
Status: COMPLETED
Conditions: Variant Angina
Interventions: DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Hip Dysplasia Registry
Status: RECRUITING
Conditions: Hip Dislocation, Congenital|Hip Dysplasia, Congenital, Nonsyndromic|Congenital Dysplasia of the Hip|Congenital Hip Dislocation|Congenital Hip Displacement|Congenital Hip Dysplasia|Dislocation Of Hip, Congenital|Dislocation, Congenital Hip|Displacement, Congenital Hip|Dysplasia, Congenital Hip|Hip Displacement, Congenital|Hip, Dislocation Of, Congenital
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Single-unit Implant-supported Prostheses Survival Using CoCr Prosthetic Abutments: Prospective Observational Study
Status: RECRUITING
Conditions: Missing Teeth|Prosthesis Survival
Interventions: DEVICE: Cobalt-Chromium (CoCr) prosthetic abutments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In Utero Treatment of Cytomegalovirus congénitale Infection With Valacyclovir
Status: COMPLETED
Conditions: Foetuses Infection|Cytomegalovirus (CMV)Infection
Interventions: DRUG: Valacyclovir arrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Nicotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Childhood B Acute Lymphoblastic Leukemia
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Thioguanine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Exercises as Treatment of Referred Pain After Total Laparoscopic Hysterectomy: Randomized Clinical Trial.
Status: RECRUITING
Conditions: Hysterectomy
Interventions: PROCEDURE: Basic and light cervical mobilization exercises|PROCEDURE: Abdominal or diaphragmatic breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Short-intensity Modified Constraint-induced Movement Therapy on Hand Function in Stroke Patients.
Status: COMPLETED
Conditions: Hemorrhagic Stroke|Ischemic Stroke|Rehabilitation
Interventions: OTHER: short-intensity modified CIMT and conventional therapy|OTHER: conventional therapy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Medical Ultrasound for Rhizarthrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rhizarthrosis
Interventions: PROCEDURE: Hand therapy (18 treatments)|PROCEDURE: Therapeutic ultrasound (18 treatments)|PROCEDURE: Combined hand therapy and therapeutic ultrasound (18 treatments)|PROCEDURE: Sham ultrasound group (18 treatments)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Antiproteinuric Efficacy of Losartan Potassium in Patients With Non-Diabetic Proteinuric Renal Diseases (0954-213)
Status: COMPLETED
Conditions: Renal Disorder
Interventions: DRUG: MK0954, losartan potassium/Duration of Treatment: 20 weeks|DRUG: Comparator: amlodipine / Duration of Treatment: 20 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Mitoxantrone hydrochloride liposome injection30mg/m2|DRUG: HomoharringtonineD1-D7(2mg/m2/day)|DRUG: Venetoclax (d4 100mg/day, d5200mg/day ,d6-d12 400mg/day)|DRUG: Cytarabine(standard-dose:d1-d7100mg/m2/day)|DRUG: Cytarabine(intermediate-dose:d1-d4100mg/m2/day, d5-d7 1g/m2)|DRUG: Mitoxantrone hydrochloride liposome injection24mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Fexofenadine Tablets 180 mg and Allegra® Tablets 180 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fexofenadine Tablets 180 mg|DRUG: Allegra® Tablets 180 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Ketotifen 4.0% Patch|DRUG: Placebo|DRUG: Olopatadine 0.2%|DRUG: Artificial tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of Peripheral Blood CD34+ Cell Dynamics Monitoring in Autologous Hematopoietic Stem Cell Transplant Mobilization
Status: NOT_YET_RECRUITING
Conditions: Granulocyte Colony-Stimulating Factor
Interventions: DRUG: PEG-rhG-CSF|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Toothpaste Containing Aloe Vera on Gingivitis
Status: COMPLETED
Conditions: Generalized Gingivitis
Interventions: DRUG: aloe vera toothpaste|DRUG: Colgate Total
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluate the PK of LY03010 Process 1 and Process 2 Drug Product vs INVEGA SUSTENNA After Intramuscular Injection in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia Patients
Interventions: DRUG: Paliperidone Palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study 2: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Minocycline Group|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research to Improve the Health of Sexual and Gender Minority Patients Through Cultural Competence and Skill Training of Community Health Center Providers and Non-clinical Staff
Status: COMPLETED
Conditions: LGBT Health|Cultural Competency|Education|Sexual Orientation|Gender Identity
Interventions: BEHAVIORAL: Clinician and Non-clinician staff training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Remote Ischemic Conditioning in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesteremia|Endothelial Dysfunction
Interventions: PROCEDURE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Headless Screw Fixation for Metacarpal Fractures in Adults.
Status: NOT_YET_RECRUITING
Conditions: Metacarpal Fractures in Adults
Interventions: PROCEDURE: intramedullary screw fixation of metacarpal fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vintafolide (MK-8109, EC145) in Participants With Progressive Adenocarcinoma of the Lung (MK-8109-008, EC-FV-03)
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung
Interventions: DRUG: Vintafolide|DRUG: Etarfolatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconnecting: Improving Interoception to Reduce Suicidal Ideation in the Military
Status: COMPLETED
Conditions: Suicidal Ideation|Interoception
Interventions: BEHAVIORAL: RISE (Reconnecting to Internal Sensations and Experiences)|BEHAVIORAL: RISE (Reconnecting to Individual Strength and Energy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection
Status: COMPLETED
Conditions: HIV|Hepatitis C|Liver Fibrosis
Interventions: DRUG: Raltegravir|DRUG: Ritonavir-boosted protease inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use a Reusable Autoinjector to Self-inject Etanercept
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis
Interventions: DRUG: Etanercept / Autoinjector A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partial Nephrectomy in Low Pressure
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Tumors Treated With Minimally Invasive Surgery
Interventions: DEVICE: Low insufflation pressure (7mm Hg) for Robotic Assisted Partial Nephrectomy|DEVICE: Standard insufflation pressure (12mm Hg) for Robotic Assisted Partial Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Immuno-bridging Between Different Manufacture Scales of Recombinant COVID-19 Vaccine (Sf9 Cell)
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Pneumonia
Interventions: BIOLOGICAL: Recombinant COVID-19 vaccine (Sf9 cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals
Status: COMPLETED
Conditions: Smoking|Tobacco Dependence
Interventions: OTHER: Teachable Moment Communication Process|OTHER: AAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
Status: COMPLETED
Conditions: Open Abdomen|Abdominal Adhesions|Trauma|Wounds and Injury
Interventions: BIOLOGICAL: Seprafilm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of KPT-330 (Selinexor) in Female Patients With Advanced Gynaecologic Malignancies
Status: COMPLETED
Conditions: Ovarian Carcinoma|Endometrial Carcinoma|Cervical Carcinoma
Interventions: DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation the Effect of Montelukast in COVID-19
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Montelukast Oral Tablet|DRUG: Montelukast plus Favicovir (Favipiravir)|DRUG: Favicovir (Standard Treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystolithiasis
Interventions: DRUG: Gabapentin|DRUG: S-ketamine|DRUG: Lidocaine|DRUG: Droperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Success of Opening Concurrent CTO leSion to Improve Cardiac Function Trial in Patients With Multi-vessel Disease
Status: UNKNOWN
Conditions: Chronic Total Occlusion of Coronary Artery|Percutaneous Coronary Intervention|Coronary Artery Disease|Viable Myocardium
Interventions: DRUG: aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor|DEVICE: coronary wires. stents or coronary balloons
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suboccipital Myofascial Release Technique in Young Adults
Status: COMPLETED
Conditions: Myofascial Release
Interventions: OTHER: Suboccipital Myofascial Release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Hormone Naive Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorb BVS vs. Drug Coated Balloon for Treatment Of ISR
Status: SUSPENDED
Conditions: Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: BVS Absorb implantation.|DEVICE: DEB Sequent Please inflation.|PROCEDURE: Control coronary angiography.|PROCEDURE: OCT visualization.|OTHER: Clinical observation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flu+CPM+rATG Conditioning Regimes for Unrelated Bone Marrow Transplantation (UBMT)(or Mobilized Peripheral Blood)in Severe Aplastic Anemia (SAA)
Status: UNKNOWN
Conditions: Anemia, Aplastic
Interventions: DRUG: cyclophosphamide, fludarabine , thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Adenocarcinoma|Lung Adenocarcinoma, Mixed Subtype|Lung Large Cell Carcinoma|Lung Squamous Cell Carcinoma|Minimally Invasive Lung Adenocarcinoma|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Placebo Administration|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Telerehabilitation on Functional Capacity, Oxidative Stress and Respiratory Parameters in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Telerehabilitation
Interventions: OTHER: stabilization exercises|OTHER: combined exercises|OTHER: Physical activity recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi)
Status: RECRUITING
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: In-Person Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Telehealth Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Internet Cognitive Behavioral Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ba Duan Jin for Patients With Pulmonary Nodules
Status: COMPLETED
Conditions: Pulmonary Nodules
Interventions: BEHAVIORAL: Ba Duan Jin|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV NaCl (Sodium Chloride) 0.9% Vs (Versus) IV NaCl 0.9% + 5% Dextrose in Pediatric ER for Dehydration
Status: UNKNOWN
Conditions: Dehydration
Interventions: OTHER: NaCl 0.9%|OTHER: NaCl 0.9 +5% dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children.
Status: COMPLETED
Conditions: Diarrhoea|Severe Malnutrition
Interventions: DRUG: Amylase resistant starch added ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib in Combination With Docetaxel in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: lapatinib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and PK of AN2728 in Adolescents With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: AN2728 Topical Ointment, 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing an Adolescent and Young Adult (AYA) mHealth Vaping Cessation Program Into Oncology Clinics
Status: RECRUITING
Conditions: Vaping|Vaping Cessation
Interventions: DEVICE: Behavioral: Quitting Program (TIQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enteroendocrine Hormonal Response After the Ingestion of Cola Beverages With Sucrose and Non-nutritive Sweeteners
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Metabolic Syndrome
Interventions: OTHER: Cola beverage with aspartame and acesulfame K|OTHER: Cola beverage with sucrose and stevia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efavirenz for Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease, Early Onset
Interventions: DRUG: Sustiva Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: UCLA Breast Cancer Survivor Health Promotion Research Study
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Diabetes Prevention Program-based lifestyle change intervention (DPP)|BEHAVIORAL: Highly Microbiota-Accessible Foods (HMAFs) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: JAB-BX102 (anti-CD73 monoclonal antibody)|BIOLOGICAL: pembrolizumab (anti-PD-1 monoclonal antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials on the Effect of Immunity 1 (Fuzheng 1) on Immune Reconstitution of HIV Patients
Status: UNKNOWN
Conditions: Acquired Immune Deficiency Syndrome Virus|HIV Infections
Interventions: DRUG: Fuzheng 1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Rosuvastatin in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Atherosclerosis|Systemic Lupus Erythematosus
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine
Status: COMPLETED
Conditions: Vestibular Migraine
Interventions: DRUG: Propranolol|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic Patients
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Punica granatum Pleniflora (Golnaar) mouth rinse|DRUG: Chlorhexidine (0.2%)|PROCEDURE: Tooth bleaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer
Status: UNKNOWN
Conditions: COPD
Interventions: DEVICE: oxyhydrogen|DEVICE: Oxygen|DRUG: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Nivolumab for Upper Tract Urothelial Carcinoma
Status: RECRUITING
Conditions: Upper Urinary Tract Urothelial Carcinoma
Interventions: DRUG: Nivolumab 100 MG in 10 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Multidisciplinary Care Pathway on the Evolution of Renal Function in Patients With Advanced Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5
Interventions: DIAGNOSTIC_TEST: Evolution of renal function|DIAGNOSTIC_TEST: Measurement of haemoglobin levels|DIAGNOSTIC_TEST: Measurement of biological parameters|DIAGNOSTIC_TEST: Measure sodium and protein consumption|BEHAVIORAL: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DEVICE: Cryoablation|COMBINATION_PRODUCT: Cryoablation combined with PD1 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor China Pharmacokinetic/Pharmacodynamic Study
Status: COMPLETED
Conditions: Stable Coronary Heart Disease (CHD)
Interventions: DRUG: Inhibition of Platelet Aggregation by "Brilinta"(Ticagrelor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Practice-Based Trial of Home BP Telemonitoring Among Minority Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Hypertension
Interventions: BEHAVIORAL: Home BP Telemonitoring (HBPTM)|BEHAVIORAL: Nurse Case Management (NCM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Rapid Pathogen Identification From Blood Cultures (RABbIT)
Status: UNKNOWN
Conditions: Bacteremia|Sepsis|Fungemia|Blood Stream Infection
Interventions: DEVICE: Filmarray Blood Culture ID (BCID) panel|DEVICE: Rosco Diagnostica ESBL/carbapenemase screen kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hybrid Device DIALYTRODE for Multimodal Neuro-monitoring of Patients With Brain Injury and Status Epilepticus
Status: WITHDRAWN
Conditions: Epilepsy|Brain Injuries
Interventions: DEVICE: Dialytrode|DEVICE: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Alternating Current Stimulation for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|MDD
Interventions: DEVICE: tACS (alpha)|DEVICE: tACS (gamma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Enhanced Education|BEHAVIORAL: Self-Efficacy|BEHAVIORAL: Motivation|BEHAVIORAL: Self-Regulation|BEHAVIORAL: Generic Risk Alert (Active Comparator)|BEHAVIORAL: Online Behavioral Obesity Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consequences From Use of Reminiscence: a Randomised Intervention Study in Ten Danish Nursing Homes
Status: COMPLETED
Conditions: Consequences for Nursing Home Residents and Staff of Integrating Reminiscence Into Daily Nursing Care.
Interventions: BEHAVIORAL: Implementation of reminiscence
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BEing Safe in Treatment
Status: COMPLETED
Conditions: Risk Behavior|Sex, Unsafe|Substance Use|Risk Reduction
Interventions: BEHAVIORAL: BEST assessment only|BEHAVIORAL: BEST assessment plus feedback report|BEHAVIORAL: Standard Counselor Training|BEHAVIORAL: Enhanced Counselor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MUSIC-CARE and Locoregional Anesthesia for Orthopedic Surgery
Status: NOT_YET_RECRUITING
Conditions: Regional Anesthesia|Music|Forearm; Injury, Superficial, Multiple (With Elbow)
Interventions: OTHER: Music-Care|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Get Going After concussioN 2.0
Status: ACTIVE_NOT_RECRUITING
Conditions: Commotio Cerebri|Mild Traumatic Brain Injury
Interventions: BEHAVIORAL: GAIN 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of MedicijnWijs on Adherence to Azathioprine Therapy in Adolescents With IBD
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: MedicijnWijs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel
Status: COMPLETED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Breast Carcinoma|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Cimetidine|DRUG: Dexamethasone|DRUG: Diphenhydramine|DRUG: Famotidine|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1, Randomized, Double-Blind, Placebo-Controlled Exploratory Study That Will Assess the Safety, Tolerability, Pharmacokinetics and Hemodynamic Response to a Single 30 Minute Intravenous Infusion of Vasomera™ (PB1046) in Adult Subjects With Stage 1 or 2 Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Placebo Single IV (Intravenous) Infusion|DRUG: Experimental: Single IV Infusion Vasomera (PB1046)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STEP: Phase IIIb Study of Benralizumab to Step-down Maintenance Therapy in Patients With Severe Eosinophilic Asthma
Status: RECRUITING
Conditions: Severe Eosinophilic Asthma
Interventions: DRUG: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symphysiolysis: Acupuncture Therapeutic Benefits: a Randomized Placebo Controlled Study.
Status: COMPLETED
Conditions: Single Embryo Pregnancy|Gestational Weeks 24-42|Pain/Sensitivity >5 on Numeric Rating Scale (NRS)
Interventions: PROCEDURE: acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in Morbidity Between a Necessity Endotracheal Suctioning Protocol Versus a Routine Endotracheal Suctioning
Status: COMPLETED
Conditions: Hypoxemia|Arrhythmias|Cardiac Arrest|Ventilator Associated Pneumonia
Interventions: PROCEDURE: Necessity endotracheal suctioning|PROCEDURE: Routine endotracheal suctioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Treatment of Anterior Shoulder Dislocation Using Knotted and Knotless Anchors
Status: COMPLETED
Conditions: Shoulder Dislocation
Interventions: DEVICE: knotted anchors (SutureTak biocomposite 3.0 mm)|DEVICE: knotless anchors (PushLock biocomposite 2.9 mm knotless)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma
Interventions: RADIATION: High Dose Radiation|DRUG: Systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy Subjects
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Placebo|DRUG: Vofopitant|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Venclose RF Ablation System for the Treatment of IPVs
Status: COMPLETED
Conditions: Chronic Venous Insufficiency
Interventions: DEVICE: Radiofrequency (RF) Thermal Ablation of Incompetent Perforator Veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dumbbell Exercise on Arteriovenous Fistula in Patients With Hemodialysis
Status: UNKNOWN
Conditions: Arteriovenous Fistula
Interventions: BEHAVIORAL: The handgrip exercise|BEHAVIORAL: The dumbbell exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validating a New Non-invasive Approach to Testing Lidocaine Effectiveness
Status: COMPLETED
Conditions: ADHD|Controls
Interventions: DRUG: Lidocaine gel|DRUG: Placebo|DRUG: Injected lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis
Status: TERMINATED
Conditions: Tendonitis|Bursitis
Interventions: DRUG: Ketoprofen Topical Patch 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Intervention in Infants - Pilot
Status: COMPLETED
Conditions: Vitamin D|Supplementation
Interventions: DIETARY_SUPPLEMENT: cholecalciferol (D3)|DIETARY_SUPPLEMENT: cholecalciferol (D3)|DIETARY_SUPPLEMENT: cholecalciferol (D3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: DEVICE: reamed, interlocking intramedullary nail|DEVICE: locking periarticular plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms|Metastatic Cancer|Advanced Cancer|Solid Tumor|Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer Stage IIIB|Non Small Cell Lung Cancer
Interventions: DRUG: Niraparib|DRUG: TSR-042|DRUG: Carboplatin-Paclitaxel|DRUG: Bevacizumab|DRUG: TSR-022|DRUG: Carboplatin-Pemetrexed|DRUG: Carboplatin-Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of OPC-1085EL Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: OPC-1085EL ophthalmic solution|DRUG: Carteolol long-acting ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Telerehabilitaion Program on Gait and Balance in Patients After Hip Surgery
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Hip Injuries
Interventions: BEHAVIORAL: training with video therapy|BEHAVIORAL: conventional exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Management Program
Status: NOT_YET_RECRUITING
Conditions: Stress|Anxiety
Interventions: BEHAVIORAL: Cyclic Sighing Breathing|BEHAVIORAL: Box Breathing|BEHAVIORAL: Hypnosis|BEHAVIORAL: Audiobook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Materiovigilance After Urinary Incontinence or Prolapse Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Organ Prolapse|Rectal Prolapse|Urinary Stress Incontinence
Interventions: PROCEDURE: urinary incontinence, pelvic organ or rectal prolapse surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Double-blind, Parallel-group Assessment of the Safety and Efficacy of Telmisartan 40mg Plus Hydrochlorothiazide 12.5mg (Micardis Plus) in Comparison With Losartan 50mg Plus Hydrochlorothiazide 12.5mg in Taiwanese Patients With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: telmisartan 40 mg/hydrochlorothiazide 12.5 mg|DRUG: losartan 50 mg/hydrochlorothiazide 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: recombinant human interleukin-21|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin Addition to Antipsychotic Treatment in Chronic Schizophrenia Patients
Status: COMPLETED
Conditions: Chronic Schizophrenia
Interventions: DRUG: Curcumin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrogel Blister Patch Prototype Treatment for Foot Blisters on the Heel
Status: COMPLETED
Conditions: Blister
Interventions: DEVICE: Experimental Blister Patch|DEVICE: Marketed Pflaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients with Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Carcinoma|Stage IV Breast Cancer AJCC V6 and V7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of DHEA in Pulmonary Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: DHEA tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement
Status: UNKNOWN
Conditions: Sleep Duration on the First Night After Surgery
Interventions: DRUG: Zolpidem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: