pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Romiplostim to Prevent Low Platelet Counts in Children and Young Adults Receiving Chemotherapy for Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Solid Tumor, Childhood|Solid Carcinoma
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast Induced Nephropathy in Patients With Advanced Renal Dysfunction Undergoing Coronary Interventions
Status: COMPLETED
Conditions: Kidney Disease, Chronic|Ischemic Heart Disease
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of LCZ696 Compared to Placebo in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: LCZ696|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infection
Interventions: DRUG: DOR/ISL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis
Status: RECRUITING
Conditions: Solid Tumor
Interventions: RADIATION: Re-irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiemetic Efficacy of Ondansetron Versus Metoclopramide
Status: UNKNOWN
Conditions: Acute Gastroenteritis|Vomiting
Interventions: DRUG: Ondansetron|DRUG: metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Dermal - Living Skin Replacement (Dermal - LSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Treatment of Biliary Strictures After LTX: Balloon Dilatation Versus Stent Placement
Status: COMPLETED
Conditions: Biliary Obstruction|Biliary Stenosis|Biliary Stricture
Interventions: PROCEDURE: endoscopic balloon dilatation|PROCEDURE: plastic stent placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: En Bloc Bladder Tumor Resection: Prospective Randomized Study
Status: RECRUITING
Conditions: Urothelial Carcinoma Bladder|Bladder Cancer
Interventions: PROCEDURE: En bloc transurethral resection of bladder tumor (TURBT)|PROCEDURE: Conventional TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study to Evaluate the Safety of R306465, a Drug in Development for Cancer and to Study the Absorption, Break Down and Elimination in Patients With Advanced Solid Malignancies.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: R306465
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of On-demand Therapy With Clomipramine and Sildenafil Combination in Premature Ejaculation
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DRUG: CDFR0812-15/25mg|DRUG: CDFR0812-15/50mg|DRUG: Condencia|DRUG: CDFR0812-Placebo|DRUG: Condencia-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide for Preventing Chronic Lung Disease in Premature Infants
Status: COMPLETED
Conditions: Lung Diseases|Bronchopulmonary Dysplasia
Interventions: DRUG: iNO|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Application of Three-Dimensionally Printed Navigational Template in Lung Biopsy
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: OTHER: CT-guided lung biopsy|DEVICE: Template-guided lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Levofloxacin Combined With Endovascular Thrombectomy for Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Levofloxacin|DRUG: Levofloxacin simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treadmill Exercise and GM-CSF Study to Improving Functioning in Peripheral Artery Disease (PAD)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: BEHAVIORAL: Supervised Treadmill Exercise Therapy|OTHER: Health education sessions (Control)|DRUG: granulocyte macrophage colony stimulating factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor-Alloantigen-Reactive Regulatory T Cell (darTreg) Therapy in Renal Transplantation (The ONE Study )
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: darTreg infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
Status: RECRUITING
Conditions: Healthy|Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: Ketamine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on the Risk of Allergy-like Reactions After Intra-arterial or Intra-venous Injection of the Marketed X-ray Contrast Medium Iopromid
Status: COMPLETED
Conditions: Contrast Medium
Interventions: DRUG: Iopromide (Ultravist, BAY86-4877)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Grade Glioma|Recurrent Childhood Pilocytic Astrocytoma|Recurrent Neurofibromatosis Type 1|Recurrent Visual Pathway Glioma|Refractory Neurofibromatosis Type 1|Refractory Visual Pathway Glioma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Pharmacokinetic Study of ND0612 Delivered as a Continuous Subcutaneous in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: LD/CD SC solution|DRUG: Entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration of Trimethylamine Oxide (TMAO) in Blood Plasma as a Risk Factor for Vascular Cerebral Damage
Status: UNKNOWN
Conditions: Vascular Diseases|Leukoaraiosis|Ischemia, Cerebral
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)|DIAGNOSTIC_TEST: Blood samples collection|DIAGNOSTIC_TEST: Neuropsychological tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011)
Status: RECRUITING
Conditions: Alzheimer Disease|Alzheimer Disease 1|Alzheimer Disease 2|Alzheimer Disease 3|Alzheimer Disease, Early Onset|Alzheimer Disease, Late Onset|Alzheimer Disease 9|Alzheimer Disease 4|Alzheimer Disease 7|Alzheimer Disease 17|Alzheimer's Dementia Late Onset|Alzheimer Disease 5|Alzheimer Disease 6|Alzheimer Disease 8|Alzheimer Disease 10|Alzheimer Disease 11|Alzheimer Disease 12|Alzheimer Disease 13|Alzheimer Disease 14|Alzheimer Disease 15|Alzheimer Disease 16|Alzheimer Disease 18|Alzheimer Disease 19|Dementia|Dementia Alzheimers|Dementia, Mild|Dementia of Alzheimer Type|Dementia Moderate|Dementia Senile|Mild Cognitive Impairment|Mild Dementia|MCI|Cognitive Impairment|Cognitive Decline|Cognitive Impairment, Mild
Interventions: DEVICE: Sensory Stimulation System (GS120) - Active|DEVICE: Sensory Stimulation System (GS120) - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illness
Status: ENROLLING_BY_INVITATION
Conditions: Smoking|Smoking Cessation|Tobacco Use Cessation
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: "Nudges"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Shedding and Immunogencity of Different Formulations of FluMist in Children 24 to <48 Months of Age
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: FluMist trivalent (2015-2016)|BIOLOGICAL: FluMist Quadrivalent (2015-2016)|BIOLOGICAL: FluMist Quadrivalent (2017-2018)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
Status: RECRUITING
Conditions: Complex Regional Pain Syndrome
Interventions: DRUG: BRC-002|DRUG: BRC-002 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser Treatment
Status: COMPLETED
Conditions: Nevus|Hyperpigmentation
Interventions: DEVICE: Cold air cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Mindfulness-based Intervention for Older Women With Low Sexual Desire
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder|Sexual Dysfunction|Female Sexual Dysfunction
Interventions: BEHAVIORAL: mindfulness-based multicomponent intervention|BEHAVIORAL: general health education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and Children
Status: ACTIVE_NOT_RECRUITING
Conditions: RSV Infection
Interventions: BIOLOGICAL: RSV 6120/∆NS1|BIOLOGICAL: RSV 6120/F1/G2/∆NS1|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Educational Intervention on Provider Knowledge for the Support of Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|OTHER: Interview|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Obatoclax Mesylate in Combination With Carboplatin and Etoposide Compared With Carboplatin and Etoposide Alone in Chemotherapy-Naive Patients With Extensive-Stage Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Obatoclax Mesylate, Carboplatine and Etoposide|DRUG: Carboplatin and Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilates, Postural Global Reeducation and Ball Exercises
Status: COMPLETED
Conditions: Strength, Muscle|Endurance , Physical|Flexibility
Interventions: OTHER: Pilates Group|OTHER: Segmented Dynamic Exercises Group|OTHER: Global Postural Reeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Palm Olein, Olive Oil and Lard and on Risk Markers of Cardiovascular Disease
Status: UNKNOWN
Conditions: Cardiovascular Disease|Metabolic Syndrome
Interventions: OTHER: Palm olein vs olive oil and lard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Clascoterone Cream 1% in Facial Acne Vulgaris
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Clascoterone|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ajuvant Chemotherapy and Immunotherapy in Patients With Esophageal, Esophageal- Gastric Junction Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Gastroesophageal Cancer|Immunotherapy|Adjuvant
Interventions: DRUG: Chemotherapy Drugs, Cancer|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy
Status: COMPLETED
Conditions: Chronic Pain|Opioid Abuse, Unspecified Use
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement|BEHAVIORAL: Conventional Support Group (SG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-LY3950321-01 Biodistribution and Safety Study
Status: COMPLETED
Conditions: Diagnostic Agent Adverse Reaction|Radiation Exposure
Interventions: DRUG: 18F-LY3950321|PROCEDURE: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intestinal Barrier Function and Probiotics.
Status: COMPLETED
Conditions: Intestinal Permeability|Challenge Test|Intestinal Health|Inflammation
Interventions: DIETARY_SUPPLEMENT: Priobiotic supplement VSL#3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GANfort® in Patients With Primary Open Angle Glaucoma or Ocular Hypertension Who Are Insufficiently Responsive to Monotherapy
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Fixed combination 0.3 mg bimatoprost and 5 mg timolol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Arthroscopic debridement with stem cell transplantation|PROCEDURE: Arthroscopic debridement only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal and Peripheral Hemodynamic Function in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: ruboxistaurin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque Psoriasis Naive to Systemic Treatment
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Fumaric Acid Esters|DRUG: Methotrexate|DRUG: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Neoadjuvant Chemotherapy Used in the Perioperative Treatment.
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Tislelizumab|DRUG: SOX/XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Laser Vision Surgery, Phakic Intraocular Lens Implantation, Cataract Surgery, and Pupil Dilation on the Iris Recognition Scanner Function of Smartphone
Status: COMPLETED
Conditions: Cataract|Myopia|Myopic Astigmatism
Interventions: DEVICE: iris recognition scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: clomiphene citrate with ethinyl esteradiol|DRUG: clomiphene citrate with plasebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty
Status: TERMINATED
Conditions: Rotator Cuff Injuries|Anesthesia; Functional
Interventions: DRUG: Ropivacaine|DRUG: Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DRUG: Gefapixant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pembrolizumab in Combination With Lenvatinib in Metastatic Uveal MElanoma Patients (PLUME)
Status: RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: Pembrolizumab 25 MG/1 ML Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Brain Stem Glioma|Childhood Mixed Glioma|Fibrillary Astrocytoma|Giant Cell Glioblastoma|Glioblastoma|Gliosarcoma|Untreated Childhood Anaplastic Astrocytoma|Untreated Childhood Brain Stem Glioma|Untreated Childhood Fibrillary Astrocytoma|Untreated Childhood Giant Cell Glioblastoma|Untreated Childhood Glioblastoma|Untreated Childhood Gliosarcoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temozolomide|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Pilot Study of Farnesoid X Receptor (FXR) Agonist in Non-alcoholic Fatty Liver Disease (NAFLD) Patients
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: DRUG: Px-104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influences of Long Term Hormone Therapy on Physical Fitness and Vascular Function in Transgender Women
Status: COMPLETED
Conditions: Transgender Women
Interventions: OTHER: Estradiol|OTHER: Estradiol and Anti-Androgen|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Assess if ABP710 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis Compared to Infliximab
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: ABP 710|BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transtympanic Ringer's Lactate for the Prevention of Cisplatin Ototoxicity
Status: UNKNOWN
Conditions: Hearing Loss
Interventions: DRUG: Ringer's Lactate (0.03% Ciprofloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Interaction Between TRUVADA™ and BILR 355 BS Plus Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 BS|DRUG: Ritonavir|DRUG: TRUVADA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus
Status: UNKNOWN
Conditions: Uremic Pruritus
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Analgesia on Success of External Version: Comparison of Spinal Anesthesia Versus Sedation
Status: UNKNOWN
Conditions: Breech Presentation
Interventions: DRUG: Midazolam|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Pembrolizumab In Patients With Immune Checkpoint Inhibitor Naïve Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Melanoma, Uveal
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of the Atalante Exoskeleton in Patients Presenting an Hemiplegia Due to Cerebrovascular Accident
Status: COMPLETED
Conditions: Stroke|Stroke, Acute|Stroke, Subacute|Chronic Stroke
Interventions: DEVICE: Use of the Atalante exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Single and Multiple Doses of Oral Insulin or Placebo in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ORMD-0801 (qd)|DRUG: ORMD-0801 (bid)|DRUG: ORMD-0801 (tid)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies
Status: RECRUITING
Conditions: Pancreatic Cyst
Interventions: PROCEDURE: 1). EUS-FNA plus MFB|PROCEDURE: 2). EUS-FNA Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Human Study of IBI101 in Chinese Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: IBI101|DRUG: IBI101|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Intracoronary Stenting With or Without Abciximab, an Anti-Platelet Therapy, and Conventional Coronary Angioplasty With Abciximab
Status: COMPLETED
Conditions: Angioplasty, Transluminal, Percutaneous Coronary
Interventions: OTHER: Angioplasty|OTHER: Intracoronary Stent|DRUG: Abxicimab|DRUG: Heparin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation
Status: TERMINATED
Conditions: Human Microbiome
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2)
Status: COMPLETED
Conditions: Diabetic Polyneuropathy
Interventions: DRUG: Thioctic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Standardized Consent for Urogynecological Procedures on Patient Satisfaction
Status: COMPLETED
Conditions: Urinary Incontinence|Pelvic Organ Prolapse
Interventions: OTHER: Standardized visual presentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Expert Statements Concerning the Tapering of Oral Corticosteroids (OCS) for the Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Brainstorming 1|OTHER: Ranking Round 1|OTHER: Ranking Round 2|OTHER: Ranking Round 3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Pharmacokinetic Characteristics and Safety Between HIP2001 and HGP2001 in Healthy Volunteers
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: HIP2001|DRUG: HGP2001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects
Status: COMPLETED
Conditions: Huntington Disease|Tardive Dyskinesia
Interventions: DRUG: LPM3770164 sustained release tablet|DRUG: LPM3770164 sustained release tablet simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics.
Status: UNKNOWN
Conditions: Depressive Episode|Depressive Disorder|Bipolar Disorder
Interventions: DEVICE: Active Theta Burst Stimulation (TBS)|DEVICE: Sham Theta Burst Stimulation (TBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 In Patients With Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CAVA Multicentre Dizziness Trial
Status: RECRUITING
Conditions: Ménière's Disease|Vestibular Migraine|Benign Paroxysmal Positional Vertigo (BPPV)
Interventions: DEVICE: The continuous ambulatory vestibular assessment (CAVA) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CBT Versus CBT With Virtual Reality Exposure for Social Anxiety Disorder and Agoraphobia
Status: RECRUITING
Conditions: Social Anxiety Disorder|Agoraphobia
Interventions: BEHAVIORAL: CBT with virtual reality exposure therapy|BEHAVIORAL: CBT in vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Articular Cartilage Defects
Status: UNKNOWN
Conditions: Degenerative Arthritis|Chondral Defects|Osteochondral Defects
Interventions: PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone marrow mesenchymal stem cell implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIGER-1: Safety and Efficacy Study of Rociletinib (CO-1686) or Erlotinib in Patients With EGFR-mutant/Metastatic NSCLC Who Have Not Had Any Previous EGFR Directed Therapy
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Rociletinib Mono-Therapy|DRUG: Erlotinib Mono-Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors
Status: COMPLETED
Conditions: Melanoma|Prostate Adenocarcinoma
Interventions: BIOLOGICAL: PEG-BCT-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchial Epithelium of Children With Post-infectious Bronchiolitis Obliterans
Status: RECRUITING
Conditions: Bronchiolitis Obliterans
Interventions: DIAGNOSTIC_TEST: Study morphological and functional of respiratory epithelium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cost-Minimization Analysis After a Targeted Intervention for EGD and Colonoscopy
Status: COMPLETED
Conditions: Primary Focus of the Study is Cost-minimization Analysis
Interventions: BEHAVIORAL: Debriefing endoscopists of the procedure accessory costs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Avelumab in Relapsed or Refractory Extranodal Natural Killer/T-cell Lymphoma[AVENT STUDY]
Status: UNKNOWN
Conditions: Lymphoma, Extranodal NK-T-Cell
Interventions: DRUG: avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
Status: RECRUITING
Conditions: Hemophilia A|Hemophilia B
Interventions: DRUG: marstacimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pétale® (Small Hearing Test Equipment for Children) for the Screening of Hearing Disorders in Children From 9 Months to 3 Years Old by the General Practitioner or Pediatrician
Status: UNKNOWN
Conditions: Petale|Hearing Disorders|Child Development
Interventions: DEVICE: Petale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FSH in GnRH-AntagoniST Controlled Ovarian Hyperstimulation Cycles (FAST)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Urofollitrophin|DRUG: Follitrophin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dysphagia After Transesophageal Echocardiography in Acute Stroke - Follow Up Trial
Status: RECRUITING
Conditions: Ischemic Stroke, Acute|Dysphagia Following Cerebrovascular Accident
Interventions: DIAGNOSTIC_TEST: Flexible Endoscopic Evaluation of Swallowing (FEES) ; Transesophageal Ecocardiography (TEE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trastuzumab for 6 Months or 1 Year in Treating Women With Nonmetastatic Breast Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|GENETIC: polymorphism analysis|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss
Status: COMPLETED
Conditions: Female Pattern Hair Loss
Interventions: DRUG: Topical minoxidil 5% in 90% ethanol and 5% propylene glycol|DRUG: Topical minoxidil 5% in pure ethanol alone|OTHER: Placebo (Ethanol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder|Inflammation
Interventions: DRUG: Celecoxib|DRUG: Minocyclin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ascites Replacement Strategy on Time to 1st Flatus After LDLT
Status: COMPLETED
Conditions: Living Donor Liver Transplantation
Interventions: DRUG: Ascites replacement with albumin and hartmann's solution|DRUG: Ascites replacement with hartmann's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minimally Invasive Pancreatico-duodenectomy
Status: COMPLETED
Conditions: Pancreaticoduodenectomy
Interventions: PROCEDURE: Laparoscopic pancreaticoduodenectomy|PROCEDURE: Open pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Palonosetron IV to Prevent Postoperative Nausea and Vomiting in Pediatric Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Palonosetron|DRUG: Ondansetron|DRUG: Placebo to Ondansetron|DRUG: Placebo to Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Status: RECRUITING
Conditions: Phantom Limb
Interventions: DEVICE: Boston Scientific Stimulator Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Warfarin Versus Aspirin in Patients With Atrial Fibrillation and Chronic Kidney Disease
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Chronic Kidney Disease
Interventions: DRUG: warfarin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bariatric Surgery and Reactive Hypoglycemia
Status: COMPLETED
Conditions: Obesity With Complications|Morbid Obesity|Reactive Hypoglycemia|Bariatric Surgery
Interventions: PROCEDURE: Gastric Bypass|PROCEDURE: Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Theta Burst in Chronic Pain: A Biomarker Study
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: DEVICE: Intermittent Theta Burst Stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rel. BA of Empagliflozin (BI 10773)/Linagliptin FDC Tbl, Comparison With Mono-components, With a Second FDC Tablet and Influence of Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 10773/linagliptin|DRUG: BI 10773/linagliptin|DRUG: BI 10773/linagliptin SID|DRUG: BI 10773/linagliptin FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of an Audit and Feedback Intervention With Quality Improvement Toolbox in Intensive Care
Status: COMPLETED
Conditions: Pain Management|Critical Care|Quality Improvement
Interventions: BEHAVIORAL: Audit and Feedback|BEHAVIORAL: Toolbox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery
Status: COMPLETED
Conditions: Severe Mitral Regurgitation|Preserved Ventricular Ejection Fraction
Interventions: OTHER: Mitral regurgitation surgery such as mitral valve replacement or repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Open-label, Multiple-dose, Crossover Study to Investigate the Pharmacokinetic Drug Interaction Between Rosuvastatin and Telmisartan in Healthy Volunteer
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Crestor 20mg(Rosuvastatin 20mg), Micardis 80mg(Telmisartan 80mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dose Effects of Hormone Therapy (Two Doses of Estradiol Associated to Progesterone) on Inflammatory Markers
Status: TERMINATED
Conditions: Healthy Symptomatic Menopausal Women
Interventions: DRUG: CLIMASTON (drug)|DRUG: 17 Beta-estradiol (2mg/day)and (1mg/day)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|KRAS Mutation-Related Tumors
Interventions: DRUG: NEROFE|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Metastatic Disease|Renal Cell Carcinoma
Interventions: DRUG: Nexavar (Sorafenib)|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Atrial Fibrillation in Pulmonary Embolism Study -SAFE-PE Study
Status: TERMINATED
Conditions: Atrial Fibrillation|Pulmonary Embolism
Interventions: DEVICE: Zenicor intermittent ECG device|DEVICE: 5 day ECG patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Relationship Between Pectus Deformities and Spinal Pathologies
Status: COMPLETED
Conditions: Pectus Deformity of Chest|Spinal Deformity
Interventions: DIAGNOSTIC_TEST: Pectus Study Form|DIAGNOSTIC_TEST: Adams Test|DIAGNOSTIC_TEST: Scoliosis Graphy|DIAGNOSTIC_TEST: Pulmonary function test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PROMINENT-Eye Ancillary Study (Protocol AD)
Status: TERMINATED
Conditions: Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: Pemafibrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Basic Triple Therapy Including Ilaprazole on the First Line Eradication Treatment of H.Pylori
Status: COMPLETED
Conditions: Helicobacter Infections
Interventions: DRUG: Noltec tab. 10mg|DRUG: Chongkundang Amoxicillin Cap. 500mg|DRUG: Cravit Tab. 500mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Sabatolimab|DRUG: Azacitidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Active Comparator in the Treatment of Depression in Patients With Schizophrenia
Status: COMPLETED
Conditions: Depression|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: olanzapine|DRUG: ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine for Thrombosis Prevention and Antiphospholipid Antibody Reduction in Primary Antiphospholipid Syndrome
Status: COMPLETED
Conditions: Antiphospholipid Syndrome
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Placebo administration|DRUG: Pregabalin administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccination of Patients With Breast Cancer With Dendritic Cell/Tumor Fusions and IL-12
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Dendritic Cell/Tumor Fusion Vaccine|DRUG: Interleukin-12|DRUG: Interleukin-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, and Efficacy of ICP-490 in Patients With Relapsed and/or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: ICP-490|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Right-sided Ablation of the Anterior Ganglionated Plexus for Neurally Mediated Syncope
Status: RECRUITING
Conditions: Syncope, Neurogenic|Syncope
Interventions: PROCEDURE: EPS, electro-anatomical mapping, ARGP ablation, and pharmacological evaluation.|PROCEDURE: EPS, electro-anatomical mapping, and pharmacological evaluation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Pramlintide on Satiety and Food Intake
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Pramlintide acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: pegylated arginine deiminase|DRUG: Gemcitabine|DRUG: Docetaxel|PROCEDURE: Tumor biopsy|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Testosterone Therapy Improve Patient-Reported Outcomes in Age-Related Testosterone Deficient Patients Undergoing Total Hip Replacement: A Randomized-Controlled Trial
Status: WITHDRAWN
Conditions: Arthroplasty, Replacement, Hip
Interventions: DRUG: Testosterone Therapy|OTHER: No Testosterone Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Joint Position Sense in Diabetic and Traumatic Transtibial Amputees
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Amputation
Interventions: DIAGNOSTIC_TEST: Joint Position Sense Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Manual Manipulation and Ex Vivo Flexible Ureteroscopic Lithotripsy to Salvage Deceased Donor Kidneys With Renal Stones: A Case Series
Status: ENROLLING_BY_INVITATION
Conditions: Manual Manipulation and Ex Vivo Flexible Ureteroscopic Lithotripsy to Salvage Deceased Donor Kidneys With Renal Stones:a New Method by
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adebrelimab and a TKI in Combination With GEMOX in First-line Treatment of Advanced Biliary Tract Cancers (BTC)
Status: RECRUITING
Conditions: Biliary Tract Cancer|Gemox Chemotherapy
Interventions: DRUG: Adebrelimab + GEMOX + TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Caffeine on Cognition in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Caffeine
Interventions: DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE