pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Three-dimensional (3D) Rectal Water Contrast Transvaginal Ultrasonography Versus Computed Colonography in the Diagnosis of Rectosigmoid Endometriosis
Status: COMPLETED
Conditions: Endometriosis, Sigmoid|Endometriosis, Rectum
Interventions: DIAGNOSTIC_TEST: Three-dimensional (3D) rectal water contrast transvaginal ultrasonography|DIAGNOSTIC_TEST: Computed colonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Substance Abuse|Substance Dependence
Interventions: DRUG: Quetiapine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Followed by Vaccine Therapy and White Blood Cell Infusions in Treating Patients With Unresectable or Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: keyhole limpet hemocyanin|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: TD-6450 MAD Study in HCV Infected Subjects
Status: COMPLETED
Conditions: Hepatitis C|HCV
Interventions: DRUG: TD-6450|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CJ-50300 in Healthy Volunteers
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: smallpox vaccine CJ-50300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Growth and Metabolic Response to GH and GnRHa Treatment Versus GH Alone in Boys Born SGA.
Status: COMPLETED
Conditions: SGA and Growth
Interventions: DRUG: growth hormone and gonadotropin-releasing hormone agonist|DRUG: growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine I-131 Iodocholesterol, Its Use in Adrenal Screening
Status: COMPLETED
Conditions: Adrenal Gland Diseases|Adrenal Gland Neoplasms
Interventions: DRUG: I-131 Iodocholesterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FGFR4 Inhibitor EVER4010001 in Combination With PD-1 Inhibitor Pembrolizumab in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: EVER4010001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Tecemotide|DRUG: Single low dose cyclophosphamide|DRUG: Placebo|OTHER: Saline|OTHER: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of a Single Tablet Regimen of Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Compared With a Single Tablet Regimen of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: FTC/RPV/TDF|DRUG: EFV/FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis
Status: RECRUITING
Conditions: Adjuvant|Treatment|Tuberculosis
Interventions: DRUG: BaiDiZiYin Pill, ShenQiYiFei Pill|DRUG: Anti tuberculosis chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease
Status: COMPLETED
Conditions: Pulmonary Hypertension|Valvular Heart Disease
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Text and Pictorial Waterpipe Tobacco Warnings Among Young Adults
Status: COMPLETED
Conditions: Waterpipe Tobacco Smoking
Interventions: BEHAVIORAL: Pictorial Warnings|BEHAVIORAL: Text Warnings|BEHAVIORAL: No Warnings (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Warm and Cold Compress to Reduce Injection Site Erythema Due to Peginterferon-beta-1a in MS
Status: COMPLETED
Conditions: MS (Multiple Sclerosis)|Erythema
Interventions: OTHER: Warm Compress Before Injection|OTHER: Cold Compress After Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Large Loop Excision of the Transformation Zone During Follicular vs. Luteal Phase of the Menstrual Cycle (LLETZ-MC)
Status: NOT_YET_RECRUITING
Conditions: Cervical Dysplasia
Interventions: PROCEDURE: LLETZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sidus(TM) Post Market Clinical Follow-up (PMCF) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-inflammatory Degenerative Joint Disease (NIDJD)|Avascular Necrosis|Osteoarthritis|Inflammatory Joint Disease (IJD)|Rheumatoid Arthritis
Interventions: PROCEDURE: Shoulder Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Protective Effect of Omega-3 Fatty Acid on Cognitive Function Among Patients With Mild Dementia
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia Disorder
Interventions: DIETARY_SUPPLEMENT: EPA|DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: MORE+JITAI|BEHAVIORAL: Supporive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Proprioception in Lower Back Pain Patients Versus Healthy Subjects : a Comparative Study on the Effects of Low- and High-frequency Muscle Vibrations
Status: COMPLETED
Conditions: Back Pain
Interventions: OTHER: Calibration|OTHER: Practice|OTHER: Measures - no vibration|OTHER: Measures - low vibration|OTHER: Measures - high vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic Pain
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: esomeprazole|DRUG: Ranitidine|DRUG: hydrotalcid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment Effects of Empagliflozin on Renal Outcomes in Cardiorenal Syndrome Type 1
Status: NOT_YET_RECRUITING
Conditions: Empagliflozin in Cardiorenal Syndrome Type 1
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Safety and Effectiveness of BORTEZOMIB Combination Therapy (Bortezomib + Doxorubicin Hydrochloride + Dexamethasone) in Previously Untreated Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib + pegylated liposomal doxorubicin HCl + dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BUILD 3: Bosentan Use in Interstitial Lung Disease
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Bosentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Citicoline/Homotaurine on PERG in Primary Open Angle Glaucoma
Status: TERMINATED
Conditions: Glaucoma
Interventions: DIETARY_SUPPLEMENT: Citicoline 500 mg plus Homotaurine 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Genetics of Cardiomyopathy and Heart Failure
Status: WITHDRAWN
Conditions: Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy|Mitochondrial Cardiomyopathy|Noncompaction Cardiomyopathy|Restrictive Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glumetinib Combined With Osimertinib in the Treatment of Relapsed and Metastatic Non-small Cell Lung Cancer Patients Who Failed to Receive EGFR Inhibitors
Status: UNKNOWN
Conditions: Negative T790M Mutation and Met Amplification
Interventions: DRUG: Glumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NI-0401 in Active Crohn's Disease
Status: COMPLETED
Conditions: Moderate to Severe Crohn's Disease
Interventions: BIOLOGICAL: NI-0401 (anti-CD3 mAB)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Iodine Balance Study to Investigate the Recommended Iodine Intake in an Elderly Population
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: BEHAVIORAL: Restrict subjects' intake of iodine-containing foods
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
Status: TERMINATED
Conditions: Hemorrhagic Stroke|Hemiparesis
Interventions: DEVICE: dual transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alisporivir Alone or Combined With RBV or PEG in Chronic Hepatitis C Genotype 2 and 3 Treatment-naïve Participants
Status: COMPLETED
Conditions: Hepatitis C|Chronic Pain
Interventions: DRUG: Alisporivir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Non-invasive Individualized Goal-directed Fluid Therapy on Outcomes Following Thoracic Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: High-risk Thoracic Cancer Surgery
Interventions: DEVICE: individualized goal-directed fluid therapy by Starling device|DEVICE: group managed by standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: zolpidem tartrate|DRUG: sodium oxybate|DRUG: Matching Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Characteristics of Pegylated Exenatide Injection (PB-119) in Subjects With Different Degrees of Renal Insufficiency and Matched Subjects With Normal Renal Function
Status: UNKNOWN
Conditions: Type2Diabetes
Interventions: DRUG: PB119
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M2VA Pain Care Pathway
Status: NOT_YET_RECRUITING
Conditions: Pain|Substance Use|Opioid Misuse|Quality of Life
Interventions: BEHAVIORAL: M2VA Pain Care Pathway (M2VAPCP)|BEHAVIORAL: Implementation Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The PostprAndial eNdothelial Function After Combination of Ezetimibe and simvAstatin Study
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Simvastatin|DRUG: Simvastatin/Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Early Lung Cancer Cells in Malignant Pleural Effusion Samples From Patients With Primary Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer|Metastatic Cancer
Interventions: GENETIC: microarray analysis|GENETIC: mutation analysis|OTHER: flow cytometry|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate Efficacy and Safety of Z-215 in Erosive Esophagitis
Status: COMPLETED
Conditions: Esophagitis, Reflux
Interventions: DRUG: Z-215 10mg|DRUG: Z-215 20mg|DRUG: Z-215 Placebo|DRUG: Rabeprazole Sodium|DRUG: Rabeprazole Sodium Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of the Evolution of Arterial and Microcirculatory Endothelial Function in Obese Patients With Type-2 Diabetes Versus Non-diabetic Obese Patients After a First Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery|Obese|Type2 Diabetes
Interventions: BIOLOGICAL: Vascularly biological assessment|BIOLOGICAL: Analysis of vasomotor endothelial function|BIOLOGICAL: Analysis of arterial compliance|BIOLOGICAL: Exploration of microcirculation|BIOLOGICAL: Venous Doppler Ultrasound|BIOLOGICAL: Arterial pressure measurement|BIOLOGICAL: Intima-Media Thickness measurement|BIOLOGICAL: Exploration of neuropathy|BEHAVIORAL: level of physical activity|OTHER: thoracic scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Music on Pain in Cancer Patients in Palliative Care Service: a Randomized Controlled Study
Status: COMPLETED
Conditions: Nursing Caries|Pain|Music Therapy
Interventions: BEHAVIORAL: music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tazemetostat for the Treatment of Relapsed/Refractory Follicular Lymphoma
Status: UNKNOWN
Conditions: Relapsed/Refractory Follicular Lymphoma With EZH2
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study to Evaluate the Effects of Mild and Moderate Renal Impairment on the Pharmacokinetics of ABT-335 and Rosuvastatin When Administered Concomitantly
Status: COMPLETED
Conditions: Dyslipidemia, Renal Insufficiency
Interventions: DRUG: ABT-335|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedative Effects in Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Comparison Study of Two Types of Nimodipine Injections in Healthy Volunteers
Status: UNKNOWN
Conditions: Bioavailability|Safety Issues|Ischemic Cerebrovascular Disease
Interventions: DRUG: Nimodipine Injection|DRUG: Nimodipine Injection (II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy With Perfusion Index (PI)
Status: NOT_YET_RECRUITING
Conditions: Perfusion Index|Plethysmography|Anesthesia, Caudal|Nerve Block|Anesthesia, Regional|Child|Inguinal Hernia Unilateral
Interventions: PROCEDURE: caudal block group|PROCEDURE: ilioinguinal-iliohypogastric nerve block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Solid Tumors
Interventions: DRUG: NKTR-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Radioiodine (RAI) Incorporation Into BRAF Mutant, RAI-Refractory Thyroid Cancers With the BRAF Inhibitor Vemurafenib: A Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Carcinoma
Interventions: DRUG: Vemurafenib|DEVICE: serial 124I PET/CT|DRUG: thyrotropin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma|Richter Syndrome|Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Gemcitabine|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Small-cell Lung Cancer|Mesothelioma|Cognitive Behavioral Therapy
Interventions: BEHAVIORAL: Run-In Sessions 1-5|BEHAVIORAL: RCT Transitions Program Sessions 1-5|BEHAVIORAL: RCT Control Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improve: Integrating Emotion Focused Components Into Psychological Therapy
Status: COMPLETED
Conditions: Unipolar Depression|Anxiety Disorder|Adjustment Disorder
Interventions: BEHAVIORAL: Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT)|BEHAVIORAL: Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: DRUG: Leuprolide Acetate|DRUG: Micronized estradiol|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture for Functional Constipation in Older Adults
Status: RECRUITING
Conditions: Constipation - Functional
Interventions: DEVICE: acupuncture|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Paclitaxol as Second Line Therapy for Advanced Gastric Cancer.
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in Vietnam
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei strain Shirota fermented milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HEP-OKS Study - Hemifield Eye Patching and Optokinetic Stimulation to Treat Hemispatial Neglect in Stroke Patients
Status: COMPLETED
Conditions: Spatial Neglect|Cerebral Stroke
Interventions: BEHAVIORAL: hemifield eye patching (HEP) + optokinetic stimulation (OKS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: VY-AADC01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression
Status: COMPLETED
Conditions: Ovarian Epithelial Carcinoma
Interventions: DRUG: PD0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CAM and Conventional Mind-Body Therapies for Chronic Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Hemodialysis Patients
Status: COMPLETED
Conditions: Acupuncture Therapy|Hemodialysis Patients|Quality of Life|Activities of Daily Living
Interventions: OTHER: Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance & Responsiveness Improvement for Metformin (TRIM)
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Psyllium powder|DRUG: Metformin Extended Release Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Ventricular Drain Placement Stealth Study
Status: RECRUITING
Conditions: External Ventricular Drain|Intracranial Pressure
Interventions: OTHER: Axium Steatlh Image Guidance|OTHER: EVD placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: TASSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Biopsy Experiences Study for Women
Status: COMPLETED
Conditions: Imaging Guided Breast Biopsy
Interventions: BEHAVIORAL: Guided Meditation|BEHAVIORAL: Music|BEHAVIORAL: Supportive Dialogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test If Giving Remune (an HIV Vaccine) Can Improve the Immune Systems of HIV-Positive Patients Who Are Also Participating in ACTG 328
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Tetanus Toxoid Vaccine|BIOLOGICAL: Hepatitis A Vaccine (Inactivated)|BIOLOGICAL: HIV-1 Immunogen|BIOLOGICAL: Hepatitis B Vaccine (Recombinant)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MT-4666
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MT-4666|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cloud-based ECG Monitoring and Healthcare Model Building on the Population With Coronary Artery Revascularization
Status: UNKNOWN
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Coronary Artery Bypass Graft
Interventions: DEVICE: Wisdom bracelet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Unresectable Primary Central Chondrosarcoma|Metastatic Primary Central Chondrosarcoma|Unresectable Primary Central Chondrosarcoma
Interventions: DRUG: Belinostat|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Decitabine and Cedazuridine|DRUG: Guadecitabine|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of a Combination of Nintedanib/Placebo in Combination With Induction Chemotherapy for Patients With Refractory or First Relapse Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: DRUG: Nintedanib and AML induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis
Status: COMPLETED
Conditions: Endocarditis, Bacterial|Opioid-use Disorder|Buprenorphine|Outpatient Parenteral Antibiotic Therapy
Interventions: BEHAVIORAL: Outpatient parenteral antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection
Status: TERMINATED
Conditions: HIV Infection|Recurrent Anal Cancer|Recurrent Breast Cancer|Recurrent Esophageal Cancer|Recurrent Gastric Cancer|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Non-small Cell Lung Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Anal Cancer|Stage IV Breast Cancer|Stage IV Esophageal Cancer|Stage IV Gastric Cancer|Stage IV Non-small Cell Lung Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Salivary Gland Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Verrucous Carcinoma of the Larynx|Stage IV Verrucous Carcinoma of the Oral Cavity|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: vorinostat|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality Control of CE-Labelled Phonak Hearing Systems (Study Part: Sonova2015-00)
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Phonak's equivalent newly developped power BTE|DEVICE: Equivalent competitor device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Mitomycin C|DRUG: Chemophase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Trazodone on the Severity of Obstructive Sleep Apnea in Insomnic Stroke Patients With Depression
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Cerebral Infarction
Interventions: DRUG: Trazodone|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Ultrasound Study in Shock Patients
Status: RECRUITING
Conditions: Septic Shock
Interventions: OTHER: Diaphragm ultrasound (DUS)|OTHER: Peripheral Muscle Ultrasound (PMUS)|OTHER: Airway occlusion pressure (P0.1)|OTHER: Medical Research Council (MRC) sum score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zyprexa and Task Engagement in Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Olanzapine (Zyprexa)|DRUG: Typicals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The HOLIDAY (HOw ALcohol InDuces Atrial TachYarrhythmias) Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Alcohol
Interventions: DRUG: Ethanol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Orthokeratology in Decreasing Myopic Progression in a Young Adult Population Enrolled in a Professional Optometric Curriculum
Status: UNKNOWN
Conditions: Myopia Progression
Interventions: DEVICE: OrthoK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rabeprazole Based Sequential-Concommitant Hybrid Therapies for H. Pylori Infections
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: RA5-RACM7|DRUG: RA3-RACM7|DRUG: RA7-RACM7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICBT for Pain-predominant FGIDs in Children and Adolescents: an Implementation Study.
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders|Irritable Bowel Syndrome|Dyspepsia|Functional Abdominal Pain
Interventions: BEHAVIORAL: Exposure-based internet-delivered CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety, Tolerability and Efficacy of LJN452 in Patients With Primary Bile Acid Diarrhea.
Status: COMPLETED
Conditions: Primary Bile Acid Diarrhea
Interventions: DRUG: LJN452|DRUG: Placebo to LJN452
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cinnamon Bark, Water-Soluble Cinnamon Extract, and Metformin for Treatment of Type 2 DM.
Status: TERMINATED
Conditions: Diabetes
Interventions: DRUG: Group 1: Metformin|DIETARY_SUPPLEMENT: Group 2: Cinnamon Bark|DIETARY_SUPPLEMENT: Group 3: Cinnulin PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumors|Relapsed/Refractory Non-Hodgkin Lymphoma|Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: GIC-102|DRUG: GIC-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer
Status: TERMINATED
Conditions: Breast Cancer|Colorectal Cancer|Pain
Interventions: DRUG: Capecitabine|DRUG: Celecoxib|PROCEDURE: Radiation Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis Due to Hepatitis B|Cirrhosis Due to Hepatitis C|Gastroesophageal Varices
Interventions: DRUG: Carvedilol|DRUG: Berberine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute Treatment of Migraine With Nausea
Status: COMPLETED
Conditions: Migraine With and Without Aura
Interventions: DRUG: Naltrexone and Acetaminophen Combination|DRUG: Sumatriptan 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimum Alveolar Concentration of Sevoflurane With Nitrous Oxide Inducing Isoelectric EEG
Status: COMPLETED
Conditions: Middle Aged Patients|General Anesthesia
Interventions: DRUG: Sevoflurane+Nitrous oxide|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate and Intrapartum Fetal Distress
Status: COMPLETED
Conditions: Fetal Distress
Interventions: DRUG: Sildenafil 50 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Erlotinib Efficacy and Safety as the 2nd/3rd Treatment in NSCLC With EGFR M(-) and C-met(-)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Erlotinib 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research of UCDA Reducing Medication Regimen in Stable PBC
Status: RECRUITING
Conditions: Primary Biliary Cholangitis
Interventions: DRUG: ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of 'AVI' Stent for Treating Coronary Revascularization
Status: UNKNOWN
Conditions: Ischemic Heart Disease|Myocardial Ischemia|Coronary Disease|Acute Coronary Syndrome
Interventions: DEVICE: AVI® Arsenic trioxide drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation of Cough Variant Asthma Treated in Combination of Chanqin Granules.
Status: UNKNOWN
Conditions: Cough Variant Asthma
Interventions: DRUG: Chanqin granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Selinexor (KPT- 330), Lenalidomide, & Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Autonomic Dysfunction in Patients With Familial Mediterranean Fever
Status: RECRUITING
Conditions: Familial Mediterranean Fever|Autonomic Dysfunction
Interventions: DIAGNOSTIC_TEST: Composite Autonomic Symptom Score-31|DIAGNOSTIC_TEST: r-r interval variability with normal breathing|DIAGNOSTIC_TEST: r-r interval variability with deep breathing|DIAGNOSTIC_TEST: Valsalva ratio|DIAGNOSTIC_TEST: 30:15 ratio|DIAGNOSTIC_TEST: sympathetic skin response|DIAGNOSTIC_TEST: blood pressure response to standing|DIAGNOSTIC_TEST: blood pressure response to sustained handgrip test|OTHER: Hospital anxiety and depression scale|DIAGNOSTIC_TEST: Fibromyalgia rapid screening tool|OTHER: Familial Mediterranean Fever Quality of life scale|OTHER: Jenkins Sleep Evaluation Scale|OTHER: The Fatigue Severity Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids
Status: COMPLETED
Conditions: Asthma|Obesity
Interventions: DIETARY_SUPPLEMENT: omega-3 polyunsaturated fatty acids|DRUG: Omega-3 Fatty Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Large B-Cell Diffuse Lymphoma
Interventions: DRUG: Oral azacitidine|DRUG: R-ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of VAL-339851 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: VAL-339851|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana
Status: COMPLETED
Conditions: Mansonella Perstans Infection|Buruli Ulcer|Tuberculosis|Co-infection
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IO vs IV Vancomycin in Tourniquetless TKA
Status: RECRUITING
Conditions: Infection, Surgical Site
Interventions: DRUG: Intraosseous Vancomycin Injection|DRUG: Intravenous Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease
Status: UNKNOWN
Conditions: Non-alcoholic Fatty Liver Disease|Sleep Apnea, Obstructive
Interventions: DIAGNOSTIC_TEST: OSA screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Observation vs Progesterone Treatment for Management of Uterine Arteriovenous Malformation
Status: UNKNOWN
Conditions: Arteriovenous Malformations
Interventions: DRUG: MedroxyPROGESTERone Injection [Depo-Provera]|DEVICE: Other
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Nurture Intervention in the NICU at The Valley Hospital
Status: COMPLETED
Conditions: Premature Birth|Obstetric Labor, Premature
Interventions: BEHAVIORAL: Family Nurture Intervention (FNI)|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: WHO QualityRights E-training in Ghana
Status: COMPLETED
Conditions: Knowledge|Attitudes|Practices
Interventions: OTHER: WHO QualityRights e-training|OTHER: WHO COVID-19 online training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Topical Application of Tranexamic Acid and Postoperative Blood Loss in Femoral Neck Fractures
Status: TERMINATED
Conditions: Femoral Neck Fracture
Interventions: DRUG: Tranexamic Acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Television Cartoons in Patients Younger Than 3.5 Years During Echocardiography
Status: COMPLETED
Conditions: Echocardiography|Pediatrics
Interventions: PROCEDURE: echocardiography|BEHAVIORAL: Watching Animated cartoons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility and Acceptability Followed by Effectiveness of bCPAP for Treatment of Children Aged 1-59 Months With Severe Pneumonia in Ethiopia
Status: COMPLETED
Conditions: Severe Pneumonia
Interventions: DEVICE: Bubble CPAP|DEVICE: Low flow oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
Status: COMPLETED
Conditions: Refractive Error|Myopia
Interventions: DEVICE: Habitual Silicone Hydrogel Contact Lens|DEVICE: narafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contingency Management of Alcohol Abuse in the Severely Mentally ILL
Status: COMPLETED
Conditions: Alcohol Abuse|Schizophrenia|Bipolar Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Needle Tip Location by the Position of the Operator During Ultrasound Guided LIJV Catheterization.
Status: UNKNOWN
Conditions: Catheterization, Central Venous
Interventions: OTHER: Position change|OTHER: Conventional position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tolerability, Safety and Pharmacokinetics of Four Single-doses of BIA 6-512 (Trans-resveratrol) and Their Effect on the Levodopa Pharmacokinetics
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Madopar® HBS 125|DRUG: Placebo|DRUG: BIA 6-512 25 mg dose|DRUG: BIA 6-512 50 mg dose|DRUG: BIA 6-512 100 mg dose|DRUG: BIA 6-512 200 mg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on Clioquinol in Drug-resistant Childhood Epilepsy: an Exploratory Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy Intractable
Interventions: DRUG: Clioquinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Masked Comparison of a New PEG Based Artificial Tear and Optive for Comfort, Vision & Wear Time in Patients Wearing Contact Lenses
Status: COMPLETED
Conditions: Comfort, Vision and Wear Time
Interventions: DRUG: New PEG based artificial tear|DRUG: Optive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Inhaled Molgramostim in Non-tuberculous Mycobacterial (NTM) Infection
Status: COMPLETED
Conditions: Mycobacterium Infections, Nontuberculous
Interventions: DRUG: Inhaled molgramostim|DRUG: Antimycobacterial regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Day Before PicoPrep
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: PicoPrep|DRUG: HalfLytely|DRUG: bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT