pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Effect of Benralizumab on Allergen-Induced Inflammation in Mild, Atopic Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Dry Needling and Ischemic Compression Technique on Scalene Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Scalenus Syndrome
Interventions: OTHER: Ischemic compression|OTHER: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients
Status: COMPLETED
Conditions: Oral Cancer|Induction Chemotherapy|Programmed Cell Death 1 Inhibitor|Inductive Therapy
Interventions: DRUG: Toripalimab|DRUG: Paclitaxcel|DRUG: Cisplatin|PROCEDURE: Radical surgery|RADIATION: Post-operative radiotherapy/chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Tailored Activity Pacing for Symptomatic Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: BEHAVIORAL: Tailored Activity Pacing|BEHAVIORAL: General Activity Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)
Status: COMPLETED
Conditions: Tourette's Disorder|Persistent (Chronic) Motor or Vocal Tic Disorder
Interventions: BEHAVIORAL: TicHelper|OTHER: Internet Based Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Cardiotoxicity of Anthracyclines in Patients With Diffuse Large B-Cell
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Large B-Cell|Diffuse Large B-Cell
Interventions: DRUG: R-CHOP with doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of the Efficacy of Cardiac Ischemic Postconditioning With New Clinical End-points Using Novel Biomarkers
Status: COMPLETED
Conditions: Acute Myocardial Infarction With ST Elevation
Interventions: PROCEDURE: Postconditioning|DEVICE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: mesna|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Posterior Pelvic Tilt on Balance and Sensory Integration in Patients With Non-specific Low Back Pain
Status: UNKNOWN
Conditions: Biochemical Lesions Lumbar Region|Orthopedic Disorder of Spine|Back Disorder
Interventions: OTHER: pelvic tilt effect on balance, sensory integration and risk of fall
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months), in Renal Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: AEB071|DRUG: Mycophenolic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Speech in Hepatic Encephalopathy (HE)
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: BEHAVIORAL: Home Recordings|BEHAVIORAL: In-patient Recordings|BEHAVIORAL: Same-Day Study Visit - Regular Appointment|BEHAVIORAL: Same-Day Study Visit - Procedure|BEHAVIORAL: Phone Call Follow-up Visits
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding
Status: COMPLETED
Conditions: Cirrhosis, Liver|Upper Gastrointestinal Bleeding
Interventions: DRUG: Terlipressin|DRUG: Somatostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Leveraging Videos and Community Health Workers to Address Social Determinants of Health in Immigrants
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Video-Based Diabetes Self-Management Education and Support (DSMES)|BEHAVIORAL: Community Health Worker (CHW) Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antipsychotic to Treat Psychosis Syndrome
Status: UNKNOWN
Conditions: Psychotic Disorders
Interventions: DRUG: risperidone|DRUG: olanzapine|DRUG: Quetiapine|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Centralized Cord Blood Registry to Facilitate Unrelated Cord Blood Transplantation
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: HPC, Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Sunitinib and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Liver Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: sunitinib malate|OTHER: laboratory biomarker analysis|PROCEDURE: hepatic artery embolization|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Cinnamon|DIETARY_SUPPLEMENT: Ginger|DRUG: Chlorhexidine Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin Lispro SAR342434|DRUG: Insulin Lispro SAR342434
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Aerobic Training Followed by Resistance Training Enhance Aerobic Capacity in Seniors
Status: COMPLETED
Conditions: Elderly
Interventions: BEHAVIORAL: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Oesophageal Carcinoma|Gastric Adenocarcinoma
Interventions: OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of ACBT on Pulmonary Function After CABG During Phase 1 Cardiac Rehabilitation
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery
Interventions: OTHER: ACBT group|OTHER: Conventional Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomically Selected Treatment for Gastric and Gastroesophageal Junction (GEJ) Tumors
Status: COMPLETED
Conditions: Stomach Neoplasms|Esophageal Neoplasms
Interventions: DRUG: 5-fluorouracil|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings Following Abdominal Surgery
Status: WITHDRAWN
Conditions: Abdominal Reconstruction
Interventions: PROCEDURE: Vacuum-assisted closure (VAC) therapy|PROCEDURE: Gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Ability of a NIRS Module to Detect a Urodynamic Variation in Humans (DETTECH)
Status: COMPLETED
Conditions: Urinary Disorders|Urinary Incontinence|Urinary Bladder Diseases
Interventions: DEVICE: NIRS recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Incision
Interventions: DEVICE: Side 1: Final layer closure with force modulating tissue bridges (FMTB)|OTHER: Side 1: Final layer dermal closure with poliglecaprone 25 suture|DEVICE: Side 2: Final layer closure with force modulating tissue bridges (FMTB)|OTHER: Side 2: Final layer dermal closure with poliglecaprone 25 suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome
Status: COMPLETED
Conditions: Haemolytic and Uremic Syndrome
Interventions: DRUG: Azithromycin|DRUG: Placebo (glucose solution 10%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Prospective CYP2C19 Genotype Guided Dosing of Anti-Platelet Therapy in Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Cardiovascular Diseases
Interventions: GENETIC: CYP2C19 genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Use of Corticotomy for Upper Incisors Retraction
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: PROCEDURE: Corticotomy-assisted Retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An EFS to Evaluate the CGuard Prime™ Carotid Stent in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: CGuard Prime™ Carotid Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Microbiota Based Treatment of Asthma in Preschool Children
Status: COMPLETED
Conditions: Asthma in Children
Interventions: PROCEDURE: Microbiota and eosinophils based therapy|DRUG: Clinical guidelines based therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Emotional Processing in Improving the Quality of Life of Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer Female|Depressive Symptoms|Fatigue|Pain|Emotions|Inflammation
Interventions: BEHAVIORAL: Art Therapy|BEHAVIORAL: Sham Art Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium and Intraoperative Blood Loss in Meningioma Surgery
Status: COMPLETED
Conditions: Meningioma
Interventions: DRUG: Magnesium group|DRUG: Normal saline group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prehabilitation and Rehabilitation in Breast Cancer Surgery Patients - a Pilot Study
Status: COMPLETED
Conditions: Breast Cancer|Lifestyle|Rehabilitation|Prehabilitation|Surgery
Interventions: BEHAVIORAL: Prehabilitation and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Responses to Focal Vibration and Implications in Pain and Mobility for Patients With Diabetic Peripheral Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Peripheral Neuropathy
Interventions: DEVICE: Focal vibration therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Based Relaxation Program on Patients to be Performed Bronchoscopy
Status: COMPLETED
Conditions: Bronchoscopy|Virtual Reality|Glasses|Relaxation Program
Interventions: OTHER: Virtual Reality Based Relaxation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of HLX14 vs. Denosumab Prolia® in Postmenopausal Women With Osteoporosis at High Risk of Fracture
Status: ACTIVE_NOT_RECRUITING
Conditions: Postmenopausal
Interventions: BIOLOGICAL: HLX14|BIOLOGICAL: Prolia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dupilumab for Treatment of Hospitalized COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: AirFloss + BreathRx|DEVICE: AirFloss + Listerine|DEVICE: Dental Floss|DEVICE: Manual Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Children (3 to < 9 Years)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59-eH1N1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
Status: COMPLETED
Conditions: Mitochondrial Diseases|Mitochondrial Respiratory Chain Deficiencies|MELAS Syndrome|Mitochondrial Myopathies
Interventions: DRUG: KL1333|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BTK Inhibitor, DTRMWXHS-12, Used Singly or in Combination, in CLL and B-cell Lymphomas
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|B-Cell Lymphoma
Interventions: DRUG: DTRMWXHS-12|DRUG: DTRM-505|DRUG: DTRM-555
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Thymosin alpha1 & Pegylated Interferon-alpha2a to Treat Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Pegylated Interferon-alpha2a|DRUG: Thymosin alpha1 & Pegylated Interferon-alpha2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifaceted Program to Improve Interpersonal Skills of Physicians
Status: COMPLETED
Conditions: Communication Programs|Interpersonal Skill|Physician-Patient Relations
Interventions: OTHER: Interpersonal Skills Multifaceted Training Program for the physician-patient relationship
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Vitamin D on the Behaviours, Mental, and Physical Health of Prisoners
Status: RECRUITING
Conditions: Mental Wellbeing|Depression, Anxiety|Bone Density, Low|Vitamin D Deficiency|Behavior
Interventions: DIETARY_SUPPLEMENT: Vitamin D supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of TILs in the Treatment of Recurrent / Refractory Non-small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: TILs（Tumor Infiltrating Lymphocytes）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma|Recurrent Melanoma|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Synovitis in Patients With Haemophilia A
Status: RECRUITING
Conditions: Haemophilia A|Synovitis|Hemophilia Arthropathy|Sonography
Interventions: DIAGNOSTIC_TEST: Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US); Haemophilia joint health score (HJHS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creatine Supplementation for Improved Voice Performance in the Elderly
Status: SUSPENDED
Conditions: Presbyphonia
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shorter Benznidazole Regimens Compared to the Standard Regimen for Chagas Disease
Status: RECRUITING
Conditions: Chagas Disease
Interventions: DRUG: Short regimen of benznidazole|DRUG: Short treatment with benznidazole|DRUG: Standard treatment with benznidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT Scan Guide Percutaneous Biopsy of Lytic Bone Metastases of Lung Cancer : Contribution in Pathology Diagnosis and Molecular Biology
Status: UNKNOWN
Conditions: Image-Guided Biopsy - Carcinoma, Bronchogenic / Diagnosis- Outpatients
Interventions: PROCEDURE: CT scan guide percutaneous biopsy of lytic bone metastases of lung cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Randomized Parallel Group Study Comparing the Efficacy & Safety of SB206 & Vehicle Gel in the Treatment of MC (B-SIMPLE1)
Status: COMPLETED
Conditions: Molluscum Contagiosum
Interventions: DRUG: SB206 12%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Muscle Training in Patients With Subacute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Subacute Stroke|Inspiratory Muscle Training
Interventions: DEVICE: PowerBreathe|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined LASERs and PRP for Postacne Scars
Status: COMPLETED
Conditions: Atrophic Acne Scar
Interventions: DEVICE: Lasers|OTHER: Platelets Rich Plasma|COMBINATION_PRODUCT: Lasers plus Normal Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Treatment of Sleep Apnea in Prediabetes to Reduce Cardiometabolic Risk
Status: COMPLETED
Conditions: Diabetes|Sleep Apnea
Interventions: DEVICE: CPAP mask|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Vitamin D Deficiency|Invasive Breast Cancer
Interventions: DRUG: Standard of Care Neoadjuvant Chemotherapy (NAC)|DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Drug Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Live Attenuated Influenza Vaccine, CodaVax
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CodaVax-H1N1|BIOLOGICAL: Fluzone quadrivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study in Order to Evaluate Disconfort Among Outpatients Using actiTENS for Neuropathic Pain vs TENS ECO 2.
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: PROCEDURE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Attention Bias Modification Training on Reducing Depressive Symptoms
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: a word dot-probe task for training procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitochondrial Apoptotic Pathway Induced by Myocardial Ischemia-Reperfusion Injury in Human
Status: UNKNOWN
Conditions: Ischemia-reperfusion(I/R)|Cardiopulmonarybypass|the Mitochondrial Pathway|Ischemic Postconditioning
Interventions: PROCEDURE: Ischemic postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Point-Of-Care Ultrasound-Driven vs Standard Diagnostic Pathway in Emergency Department Patients With Dyspnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyspnea
Interventions: DIAGNOSTIC_TEST: Point-of-care ultrasound-driven diagnostic pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Investigation to Evaluate FlowOx2.0™ for Experimental Treatment of Spasticity
Status: UNKNOWN
Conditions: Multiple Sclerosis|Spasticity, Muscle|Pain
Interventions: DEVICE: FlowOx™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Passiflora Incarnata and Isoflavona Combination in the Treatment of Climacteric Symptoms
Status: WITHDRAWN
Conditions: Climacteric Syndrome
Interventions: DRUG: Placebo|DRUG: Active drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Temporary Filling Material Composition on the Success Rate of Endodontic Treatments
Status: UNKNOWN
Conditions: MTA|Calcium Hydroxide|Endodontic Treatment
Interventions: PROCEDURE: Carie removal|PROCEDURE: Absolute isolation|DRUG: Manipulation of the temporary filling material based on Calcium Hydroxide|DRUG: Manipulation of the temporary filling material based on Mineral trioxide aggregate|PROCEDURE: Material insertion on the root canal|PROCEDURE: Material re-insertion on the root canal accordging to the infection needs.|PROCEDURE: Definiteve canal root obturation|PROCEDURE: Definitve restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: OTF Ocular Lubricant|OTHER: Ocular Lubricant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Fatigue During Radiotherapy for Breast Cancer With and Without Homeopathy Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Homeopathy remedy|RADIATION: Radiation as adjuvant therapy for breast cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Bicarbonate for Acute Peripheral Vertigo
Status: RECRUITING
Conditions: Peripheral Vertigo
Interventions: DRUG: Diphenhydramine|DRUG: Sodium Bicarbonate|DRUG: Diphenhydramine + Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Tumor Biomarkers by Mass Spectrometry Imaging
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Cancer|Squamous Cell Carcinoma|Basal Cell Carcinoma|Non-melanoma Skin Cancer
Interventions: OTHER: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of PEG-rhG-CSF in Neutropenia After Chemotherapy
Status: UNKNOWN
Conditions: Mammary Cancer|Lymphoma|Bone Tumour|Gynecological Tumors
Interventions: DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
Status: COMPLETED
Conditions: Antisocial Behavior|Aggression
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study To Confirm Efficacy and Safety of Terlipressin in Hepatorenal Syndrome (HRS) Type 1
Status: COMPLETED
Conditions: Hepatorenal Syndrome
Interventions: DRUG: Terlipressin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of Pathological Changes of the Ophthalmic Artery in Patients With Retinal Artery Occlusion
Status: COMPLETED
Conditions: Retinal Artery Occlusion
Interventions: OTHER: MRI of the cerebral arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Safety and Feasibility of tDCS Combined With Conservative Treatment for Cervicogenic Headaches
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Patients With Metastatic or Locally Advanced (Unresectable) Chondrosarcoma
Status: COMPLETED
Conditions: Conventional Chondrosarcoma
Interventions: DRUG: IPI-926|DRUG: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Self-help Support for Lifestyle Behavior Changes Among Primary Care Outpatients With Mental Health Problems
Status: COMPLETED
Conditions: Mental Health|Risk Reduction Behavior|Primary Health Care
Interventions: BEHAVIORAL: Digital Health Profile|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and Ganciclovir in Treating Patients With Mesothelioma
Status: UNKNOWN
Conditions: Malignant Mesothelioma
Interventions: BIOLOGICAL: PA-1-STK ovarian carcinoma vaccine|DRUG: ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of a Novel Volume-stable Collagen Matrix (VCMX) in the Treatment of Single Gingival Recession Associated With Non-carious Cervical Lesion Partially Restored
Status: RECRUITING
Conditions: Gingival Recession, Localized|Tooth Abrasion
Interventions: PROCEDURE: Restorative procedure|PROCEDURE: Coronally Advanced Flap (CAF).|DEVICE: Volume-stable collagen matrix (VCMX)|DRUG: Amoxicillin 500mg|DRUG: Sodium dipyrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux
Status: RECRUITING
Conditions: Gastroesophageal Reflux|Esophageal Motility Disorders|Upper Gastrointestinal Disorder
Interventions: DIAGNOSTIC_TEST: high-resolution manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Precedex Versus Propofol-Awakening for Reducing Brain Injury Expansion
Status: COMPLETED
Conditions: Brain Injury|Intracranial Pressure
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Elacestrant|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy
Status: COMPLETED
Conditions: Hemangioma, Capillary
Interventions: DRUG: Imiquimod 5% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude
Status: COMPLETED
Conditions: High Altitude|Inhalation; Gas|Acute Mountain Sickness
Interventions: DRUG: Exercise under inhalation CO2|OTHER: Exercise under inhalation ambient air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: MDS
Interventions: DRUG: APR-246 + azacitidine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Female Elderly
Status: UNKNOWN
Conditions: The Effectiveness of Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Femal Elderly in the Community
Interventions: BEHAVIORAL: Design course
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dato-DXd|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: arbaclofen placarbil-Cohort 1|DRUG: Placebo-Cohort 5|DRUG: arbaclofen placarbil-Cohort 2|DRUG: arbaclofen placarbil-Cohort 3|DRUG: arbaclofen placarbil-Cohort 4|DRUG: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
Status: TERMINATED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Gestational Trophoblastic Tumor|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: Data Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient
Status: RECRUITING
Conditions: Traumatic Injury
Interventions: DRUG: Administration of drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Tramadol Versus Dexmedetomedine for Analgesia After Abdominal Laparoscopic Cancer Surgeries
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Tramal 1|DRUG: Tramal 2|DRUG: Dexmedetomidine 1|DRUG: dexmedetomidine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of a Novel Tetravalent Dengue Vaccine in Healthy Children and Adolescents Aged 9 to 16 Years in Latin America
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Dengue
Interventions: BIOLOGICAL: Live, attenuated, dengue serotype 1, 2, 3, 4 virus|BIOLOGICAL: Placebo: (NaCl) 0.9% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the PICO® Negative Pressure Dressing System on the Fibula Free Flap Donor Site's Skin Graft.
Status: RECRUITING
Conditions: Carcinomatous Resections|Violent Trauma
Interventions: DEVICE: PICO dressing|DEVICE: Conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Quantification of Muscle and Liver Glutathione GSH-MRS
Status: COMPLETED
Conditions: Assay Muscle|Liver Glutathione in Healthy Human
Interventions: DEVICE: Proton magnetic resonance spectroscopy (1H MRS)|OTHER: a protein rich breakfast at home|OTHER: a protein rich lunch at the Clinical Investigation Center
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Tirzepatide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil|DRUG: Azilsartan medoxomil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of SPSIPB on Postoperative Pain in Patients Undergoing Reduction Mammoplasty Surgery: Case Series
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: OTHER: Serratus posterior superior intercostal plane block (SPSIPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MK0767 Added to Insulin Therapy in Patients With Type 2 Diabetes (0767-030)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: MK0767
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Testing the BioSerenity Pulse Oximeter (EOXY) Efficacy, Performance and Safety in Healthy Volunteer
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: EOXY device|DEVICE: Gold standard oximeter|PROCEDURE: SaO2 sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating Novel Therapies in ctDNA Positive GI Cancers
Status: RECRUITING
Conditions: Colon Adenocarcinoma|Rectal Adenocarcinoma|Gastric Adenocarcinoma|Pancreatic Adenocarcinoma|Hepatocellular Carcinoma|Adenocarcinoma of Biliary Tract|Gallbladder Adenocarcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: galyfilcon A, BC 8.30|DEVICE: lotrafilcon B, BC 8.60|DEVICE: comfilcon A, BC 8.60
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compression Wraps as Adjuvant Therapy in Management of Acute Systolic Heart Failure
Status: TERMINATED
Conditions: Heart Failure; With Decompensation
Interventions: DEVICE: ACE compression wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PolyImmune {Durvalumab (MEDI4736) and Tremelimumab} & Vaccine Orchestrated Treatment for Patients With Advanced/Metastatic Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DEVICE: TDS-IM v1.0 System|BIOLOGICAL: Neoantigen DNA Vaccine|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Sevirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of RO7049665 on the Time to Relapse Following Steroid Tapering in Participants With Autoimmune Hepatitis (AIH)
Status: TERMINATED
Conditions: Autoimmune Hepatitis|Autoimmune Chronic Hepatitis
Interventions: DRUG: RO7049665|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Choline Alphoscerate on Cognitive Function in Alzheimer's Dementia
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Alfoatirin® Tab. + Aripezil® Tab.|DRUG: Aripezil® Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19 CAR T Cells in Children and Adults With Relapsed or Refractory CD19 Positive B Cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: Relapsed/Refractory B-Cell Malignancies
Interventions: DRUG: CD19 Chimeric Antigen Receptor (CAR) T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Improvement in Lung Cancer Patients Receiving Radiation With or Without Brachytherapy
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: EBR plus HDRIB|RADIATION: EBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography-computed Tomography (PET-CT) for Main & Branch Intraductal Papillary Mucinous Neoplasm
Status: COMPLETED
Conditions: Intraductal Papillary Mucinous Neoplasm
Interventions: PROCEDURE: PET-CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Deep Brain Stimulation of the Dentate Nucleus on Cerebellar Ataxia
Status: UNKNOWN
Conditions: Cerebellar Ataxia
Interventions: DEVICE: deep brain stimulation on stimulation - active|DEVICE: deep brain stimulation off stimulation - sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: L-leucyl-L-leucine Methyl Ester (LLME)|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mesna|BIOLOGICAL: Granulocyte Macrophage Colony-Stimulating Factor (GM-CSF)|PROCEDURE: Hematopoietic stem cell transplantation (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Repetitive Transcranial Magnetic Stimulation as a Treatment for Refractory Depression (rTMS)
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: Magnetic stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Moderately Hypofractionated Radiotherapy for Prostate Cancer.
Status: ENROLLING_BY_INVITATION
Conditions: Prostatic Neoplasms|Genital Neoplasms
Interventions: RADIATION: Hypofractionated IMRT using helical Tomotherapy.|RADIATION: Hypofractionated IMRT using helical Tomotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study Of Safety And Tolerability Of Pregabalin In Pediatric Patients With Partial-Onset Seizures
Status: COMPLETED
Conditions: Epilepsies, Partial
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of GSK189075 on PK Profiles of an Oral Contraceptive Pill When Given to Healthy Female Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075|DRUG: Brevicon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Vulvar Dysplasia|HPV-Related Vulvar Intraepithelial Neoplasia|Preinvasive Vulvar Disease|Vulva Intraepithelial Neoplasia|Vulvar Diseases
Interventions: DRUG: artesunate ointment 40%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Carvedilol Tablets 12.5 mg to Coreg® Tablets 12.5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol Tablets 12.5 mg|DRUG: Coreg® Tablets 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Dexlansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT