pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sleep Quality of Physiotherapy Students Quality of Life and Physical Activity Level
Status: COMPLETED
Conditions: Sleep Quality|Quality of Life|Physical Activity
Interventions: BEHAVIORAL: Pittsburgh Sleep Quality Index (PSQI)|BEHAVIORAL: International Physical Activity Questionnaire (IPAQ)|BEHAVIORAL: The Short Form 36 Health Survey (SF-36)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BTK Inhibitor BGB-3111 in Chinese Participants With Diffuse Large B-Cell Lymphoma (Non-GCB) and Indolent Lymphoma (FL and MZL)
Status: COMPLETED
Conditions: Marginal Zone Lymphoma|Follicular Lymphoma|Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Dengushield in Healthy Adults
Status: COMPLETED
Conditions: Phase 1|Dengue
Interventions: BIOLOGICAL: Dengushield 1 mg/kg (Cohort 1) intravenous|BIOLOGICAL: Dengushield 3 mg/kg (Cohort 2) intravenous|BIOLOGICAL: Placebo 3 mg/kg (Cohort 2) intravenous|BIOLOGICAL: Dengushield 7 mg/kg (Cohort 3) intravenous|BIOLOGICAL: Placebo 7 mg/kg (Cohort 3) intravenous|BIOLOGICAL: Dengushield 12 mg/kg (Cohort 4) intravenous|BIOLOGICAL: Placebo 12 mg/kg (Cohort 4) intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Peripheral Nerve Blocks With Intrathecal Morphine in Improving Analgesia After Unilateral Total Knee Arthroplasty
Status: COMPLETED
Conditions: Anesthesia|Total Knee Arthroplasty
Interventions: DRUG: Combined spinal epidural anesthesia technique with intrathecal morphine|DRUG: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block|DRUG: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block as well as sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extension Study of Herombopag for Pediatric Patients With Chronic Immune Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Herombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Implant Driver Facilitated Micro-osteo Perforation on the Rate of Tooth Movement.
Status: COMPLETED
Conditions: Tooth Movement Techniques
Interventions: PROCEDURE: implant driver facilitated micro-osteoperforations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhodiola Rosea in Adults With Attention Deficit/Hyperactivity Disorder
Status: UNKNOWN
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Rhodiola|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valvosoft First-In-Man Study in Severe Symptomatic Aortic Stenosis
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Ultrasound treatment of Calcified aortic valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Abdominal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: LPM3480392 Injection|DRUG: Placebo|DRUG: morphine hydrochloride injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction
Status: COMPLETED
Conditions: Obstructive Sleep Apnea, Obesity
Interventions: DEVICE: Standard care with a facemask.|DEVICE: SuperNO2VA™EtCO2 (Nasal Oxygenating Ventilating Apparatus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms
Status: COMPLETED
Conditions: Myeloproliferative Neoplasms of|Polycythemia Vera|Essential Thrombocythemia|Myelofibrosis
Interventions: DRUG: LY2784544
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of AH Plus Bioceramic Sealer
Status: ENROLLING_BY_INVITATION
Conditions: Root Canal Infection|Periapical Periodontitis|Periapical Diseases
Interventions: DEVICE: AH Plus Bioceramic Sealer|DEVICE: AH Plus Sealer (resin-based)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Dental Caries
Interventions: BEHAVIORAL: video modeled social story
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pre-operative Treatment for Patients With Untreated Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Resectable Pancreatic Cancer|Unresectable Pancreatic Cancer|Pancreatic Adenocarcinoma|Neoadjuvant Pancreatic Cancer
Interventions: DRUG: Paclitaxel Protein Bound (Abraxane)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration-effect Relationship of Enoxaparin for Thromboembolic Prevention
Status: WITHDRAWN
Conditions: Sars-CoV2
Interventions: DRUG: Lovenox 40 MG in 0.4 mL Prefilled Syringe|DEVICE: Ultrasound of the lower limbs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Acute Bronchodilator Effect of CHF1535 NEXThaler
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclometasone Dipropionate 100 µg + Formoterol Fumarate 6 µg|DRUG: Beclometasone Dipropionate 200 µg + Formoterol Fumarate 6 µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma
Status: COMPLETED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma
Interventions: DRUG: carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BAriatric Surgery Versus Optimal Medical Therapy on Cardiovascular Health and Atherosclerosis in Obese, Type II Diabetic Patients
Status: UNKNOWN
Conditions: Obesity|Diabetes Mellitus, Type 2|Atherosclerosis
Interventions: PROCEDURE: Gastric bypass|BEHAVIORAL: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients
Status: COMPLETED
Conditions: Medical Oncology
Interventions: DRUG: Copanlisib (BAY80-6946)|DRUG: Itraconazole|DRUG: Rifampin|DRUG: Copanlisib (BAY80-6946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome
Interventions: DRUG: HZN-1116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Calcium Acetate Oral Solution Versus Calcium Acetate Gelcaps in Healthy Volunteers
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Calcium Acetate Oral Solution 667 mg per 5 mL|DRUG: Calcium Acetate 667 mg GelCaps|DIETARY_SUPPLEMENT: Calcium Citrate 950 mg Caplets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recipient Vessels for Free Tissue Flaps in Advanced Oncologic Defects of the Midface and Scalp
Status: COMPLETED
Conditions: Head Neck Neoplasms
Interventions: PROCEDURE: Recipient vessel selected for microanastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topic Cervical Anesthesia Plus Paracervical Blockade for Pain Control During Endouterine Manual Aspiration
Status: COMPLETED
Conditions: Pain|Abortion, Spontaneous
Interventions: DRUG: Lidocain topical + paracervical blockade|DRUG: Lidocaine topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder
Status: TERMINATED
Conditions: Chronic Interstitial Cystitis|Painful Bladder Syndrome|Recurrent Urinary Tract Infection
Interventions: COMBINATION_PRODUCT: Hyperbaric Oxygen Therapy-
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Extended Release Nifedipine Tablets in Healthy Chinese Subjects
Status: UNKNOWN
Conditions: Therapeutic Equivalency
Interventions: DRUG: Extended Release Nifedipine Tablets 30 mg|DRUG: Extended Release Nifedipine Tablets 30 mg (Adalat® GITS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tolerance of Two Forms of Vitamin C in Acid-sensitive Adults
Status: COMPLETED
Conditions: Tolerance
Interventions: DIETARY_SUPPLEMENT: Calcium ascorbate|DIETARY_SUPPLEMENT: Ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: OTHER: Screening testing strategy|OTHER: No screening testing strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Buprenorphine Naltrexone-P1 A-Cocaine
Status: COMPLETED
Conditions: Cocaine-related Disorders
Interventions: DRUG: Suboxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confocal Microscopy Evaluation of Margin Clearance in Basal Cell Carcinomas in Mohs Surgery
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: PROCEDURE: Vivascope 2500 ex-vivo fluorescent confocal microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PRE.C.I.S.A - Fall Prevention and Promotion of Active and Healthy Aging
Status: COMPLETED
Conditions: Fall|Aging|Parkinson Disease|Stroke
Interventions: BEHAVIORAL: Interdisciplinary multicomponent interventions|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Anesthetic Agents Management on ECG Changes of Patients Who Were Operated Under RIVA
Status: COMPLETED
Conditions: Qt Interval, Variation in
Interventions: DRUG: Ketamine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Sunitinib In Combination With Cisplatin/Capecitabine Or Oxaliplatin/Capecitabine In Patients With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: capecitabine|DRUG: oxaliplatin|DRUG: sunitinib malate|DRUG: capecitabine|DRUG: cisplatin|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Fatigability Neuromuscular Explain Chronic Fatigue in People With Multiple Sclerosis?
Status: TERMINATED
Conditions: Sclerosis, Multiple
Interventions: OTHER: Evaluation of degree chronic fatigue.|OTHER: Questionnaires|BIOLOGICAL: Blood sample|OTHER: Cardiopulmonary evaluation|DEVICE: Capacity of muscular oxygen extraction|DEVICE: Sleep assessment|DEVICE: Metabolic fatigue|OTHER: Neuromuscular evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Breast Cancer Biospecimen Collection
Status: RECRUITING
Conditions: Breast Cancer|Invasive Breast Cancer|Carcinoma in Situ of the Breast
Interventions: PROCEDURE: Tissue Sample collection|OTHER: Blood Sample Collection|OTHER: Rectal Swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bictegravir in the Elderly Living With HIV (BICEP)
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of D3S-002 as Monotherapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations
Status: RECRUITING
Conditions: Advanced Solid Tumors With MAPK Pathway Mutations
Interventions: DRUG: D3S-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant vs. Desloratadine in EGFR-TKIs Related Pruritus Treatment
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Aprepitant|DRUG: Desloratadine|DRUG: Placebo of aprepitant|DRUG: Placebo of desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback in Decreasing Acute Radiotherapy-Induced Pain in Patients With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Carcinoma
Interventions: OTHER: LORETA Neurofeedback Training|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB
Status: RECRUITING
Conditions: Pulmonary Nodule, Solitary|Lung Cancer
Interventions: DEVICE: Ion Endoluminal System|DEVICE: superDimension Navigation System and Accessories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: LPD+α-ketoacids on Autophagy and Improving Muscle Wasting in CKD
Status: UNKNOWN
Conditions: Muscular Atrophy
Interventions: DRUG: keto-amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy/Radiotherapy Versus Concomitant Chemotherapy Followed by Radiotherapy in Stage IIIB Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small-cell Lung Cancer
Interventions: DRUG: Docetaxel 20mg/m2/week + carboplatin AUC 2/weekly - concomitant chemoradiation 2Gy/day|DRUG: Docetaxel 40mg<7m2 d1,8, 21, 28+ gemcitabine 1200mg/m2 d1,8, 21, 28 + concomitant docetaxel 20mg/m2/w+carboplatin AUC 2/w+ concomitant RDT 2Gy/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma (NHL)|Mantle Cell Lymphoma (MCL)|Chronic Lymphocytic Leukemia (CLL)|Follicular Lymphoma|Marginal Zone Lymphoma|Diffuse Large B Cell Lymphoma|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|Central Nervous System Lymphoma
Interventions: BIOLOGICAL: 8/12-Day Production of Car-T Cells|BIOLOGICAL: 8/12-Day Production of Cryopreserved Car-T Cells|BIOLOGICAL: 12-Day Production of Car-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-Acetylcysteine and Cocaine
Status: COMPLETED
Conditions: Cocaine Abuse|Cocaine Dependence
Interventions: DRUG: Cocaine|DRUG: n-Acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Immune Memory Responses to HPV Vaccination Following 2 vs 3 Doses of Quad-HPV Vaccine
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: BIOLOGICAL: Human Papillomavirus 9-valent Vaccine, Recombinant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Acquired Lipodystrophy (HAL) Classification, Measurement and Fat Response to Thiazolidinedione (TZD) (Pioglitazone)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Pioglitazone|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ION-682884 in Patients With TTR Amyloid Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Transthyretin Amyloid Cardiopathy
Interventions: DRUG: ION 682884
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Translating Telephonic Diabetes Self-management Support to Primary Care Practice
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Telephonic Diabetes Self-Management Support|OTHER: Educational Print Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammation and Neurocognitive Damage Markers in Elderly People With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Sleep Apnea|Apnea, Obstructive|Obstructive Sleep Apnea Syndrome|Inflammation|Inflammatory Response|Neurocognitive Disorders|Neurodegenerative Diseases
Interventions: DIAGNOSTIC_TEST: cortisol, BDNF, s100B, IL-1B, IL-6, IL-10, TNF-alpha
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness Rehabilitation Hematopoietic Transplantation (ovERsHOT)
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: OTHER: Specific program functional and respiratory rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Novel 99mTc-labeled Somatostatin Antaginosts in the Diagnostic Algotithm of Neuroendocrine Neoplasms
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: [99mTc]Tc-TECANT1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU)
Status: COMPLETED
Conditions: Diabetic Foot Infection|Non-healing Wound|Non-healing Diabetic Foot Ulcer
Interventions: BIOLOGICAL: TTAX01|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases|Hypoglycemic Agents|Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: Dulaglutide|DRUG: Oral antihyperglycemics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes and Quality of Life After CABG
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Surgery Patients
Interventions: PROCEDURE: Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Study in Myeloproliferative Disorders
Status: COMPLETED
Conditions: Myeloproliferative Disorders|Thrombocythemia, Essential|Polycythemia Vera|Primary Myelofibrosis
Interventions: DRUG: LY2784544
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD of BI 655075 and Establishment of BI 655075 Dose(s) Effective to Reverse Prolongation of Blood Coagulation Time by Dabigatran
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: BI 655075|DRUG: BI 655075|DRUG: Placebo|DRUG: BI 655075|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: BI 655075
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Psychological Factors in the Healing of the Diabetic Foot Ulcer
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Foot Ulcer
Interventions: BEHAVIORAL: Muscle Relaxation with Guided Imagery|BEHAVIORAL: Hypnosis with Guided Imagery|BEHAVIORAL: Neutral Guided Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Astigmatism Correction With Intrastromal Arcuate Incisions in Eyes Undergoing Cataract Surgery With Femtosecond Laser Using the Cassini Ambient With Iris Registration (ARCUATAS)
Status: COMPLETED
Conditions: Cataract|Astigmatism
Interventions: DEVICE: Calculation of the arcuate intrasomal incisions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Performance and Safety of the Medical Device Plenhyage®
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: Plenhyage® thin|DEVICE: Plenhyage® medium|DEVICE: Plenhyage® strong
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Lomvastomig|DRUG: Tobemstomig|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrapleural Administration of Bevacizumab Versus Endostar for Pleural Effusions in NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults
Status: COMPLETED
Conditions: Sarcoma|Central Nervous System Tumor
Interventions: BIOLOGICAL: dendritic cells|PROCEDURE: Surgery as needed by the patient´s tumor and stage|DRUG: Chemotherapy as needed by the patient´s tumor and stage|RADIATION: Radiation therapy as needed by the patient´s tumor and stage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low Back Pain
Interventions: DRUG: Biofreeze|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization
Status: COMPLETED
Conditions: Heart Disease|Myocardial Infarction|Acute Myocardial Infarction
Interventions: DRUG: Reteplase 10 Units (U) plus a second dose of reteplase 10 U|DRUG: Reteplase 10 U|PROCEDURE: Urgent Percutaneous Coronary Intervention (PCI)|PROCEDURE: Primary Percutaneous Coronary Intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of 3D Posture Corrective Orthosis to A Multimodal Program of Treatment Of NSNP.
Status: COMPLETED
Conditions: Neck Pain
Interventions: DEVICE: ambulatory mirror image functional re-training through wearing 3D adjustable cervicothoracic Posture Corrective Orthotic(CTPCO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on Oral Health
Status: COMPLETED
Conditions: Oral Disease
Interventions: DIETARY_SUPPLEMENT: Bactoblis|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training
Status: COMPLETED
Conditions: Hemiparesis|Stroke
Interventions: DEVICE: rTMS|BEHAVIORAL: BCI Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Luteal Antagonist Versus Conventional Treatment in Women With Severe Early Ovarian Hyperstimulation Syndrome (OHSS)
Status: UNKNOWN
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: cetrorelix (cetrotide)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Vie-Scope and Macintosh Blade Laryngoscopes in Morbidly Obese.
Status: COMPLETED
Conditions: Obesity, Morbid|Intubation Complication
Interventions: DEVICE: Laryngoscopy with Vie-Scope laryngoscope|DEVICE: Laryngoscopy with Macintosh blade laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal Surgery
Status: COMPLETED
Conditions: Anorectal Diseases|Hemorrhoids|Anal Polyp|Pilonidal Sinus|Anal Fissures
Interventions: PROCEDURE: use of different spinal anesthesia techniques
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Contrast Agent and Radiation Dose Protocol for Liver CT in Patients With HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Low radiation dose CT|RADIATION: Conventional CT (radiation)|DRUG: Low contrast dose CT|DRUG: Conventional CT (contrast agent)|OTHER: Deep-learning based contrast boosting algorithms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Comparison of EBUS-TBNA, TBMC Via a Tunnel, and TBFB Via a Tunnel in Diagnosing Mediastinal Lymphadenopathy.
Status: RECRUITING
Conditions: Lymphadenopathy Hilar|Lymphadenopathy Mediastinal
Interventions: PROCEDURE: EBUS-TBNA|PROCEDURE: EBUS-TBMC via a tunnel|PROCEDURE: EBUS-TBFB via a tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Liver in the World Trade Center Health Program General Responder Cohort and Controls
Status: COMPLETED
Conditions: Steatosis of Liver|NASH - Nonalcoholic Steatohepatitis
Interventions: DEVICE: Fibroscan of Liver|PROCEDURE: Low-dose non-contrast CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine in Women With Operable Breast Cancer
Status: TERMINATED
Conditions: Invasive Breast Carcinoma|Primary Invasive Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hyperphosphatemia|Iron Deficiency Anemia|Renal Insufficiency
Interventions: DRUG: Ferric Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cocoa Flavanols in Renal Disease
Status: COMPLETED
Conditions: End Stage Renal Disease|Endothelial Dysfunction
Interventions: OTHER: Cocoa|OTHER: Cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Citalopharm and Fluvoxamine on Platelet Response to Clopidogrel
Status: COMPLETED
Conditions: Drug Interactions Between Clopidogrel and Serotonin Reuptake Inhibitors
Interventions: DRUG: fluvoxamine|DRUG: citalopharm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does a Single Shot Femoral Nerve Block Alone Produce Appropriate Pain Relief?
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Femoral Nerve Block|DRUG: Combined nerve blocks|DRUG: Patient-controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Knee Osteoarthritis (KOA) by Injection of Autologous Adipose-derived Vascular Matrix Components (SVF) Into Joint Cavity
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Stromal vascular fraction,SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Seborrheic Keratosis
Status: COMPLETED
Conditions: Seborrheic Keratosis (SK)
Interventions: DRUG: A-101 25%|DRUG: A-101 32.5%|DRUG: A-101 40%|DRUG: A-101 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study for Effective Reversal of a Deep Rocuronium-induced Neuromuscular Block With Sugammadex in Morbidly Obese Patients
Status: COMPLETED
Conditions: Morbidly Obese Patients
Interventions: DRUG: Sugammadex 2 mg/kg|DRUG: Sugammadex. 4 mg/kg|PROCEDURE: Neuromuscular monitoring.|PROCEDURE: Clinical evaluation of residual curarization .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Toric Soft Contact Lenses After Two Weeks of Wear
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: senofilcon A toric|DEVICE: alphafilcon A toric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of APIXaban on BRAIN Protection in Patients With Sinus Rhythm and Heart Failure: APIXBRAIN-HF Trial
Status: UNKNOWN
Conditions: Heart Failure|Sinus Rhythm|Cerebrovascular Disease
Interventions: DRUG: Apixaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.
Status: RECRUITING
Conditions: Locally Advanced or Metastatic GC and GCJ Adenocarcinoma
Interventions: DRUG: LM-302|DRUG: Apatinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes of Chronic Hepatitis C Patients Post Sofosbuvir-based Treatment
Status: UNKNOWN
Conditions: Liver Fibroses|HepatoCellular Carcinoma|Cryoglobulinemia|Metabolic Disease|Diabetes Mellitus
Interventions: OTHER: Observation only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised Trial of Cabazitaxel, Docetaxel, Mitoxantrone or Satraplatin (CDMS) Plus Surgery for Prostate Cancer Patients Without Metastasis
Status: RECRUITING
Conditions: Prostate Cancer Patients
Interventions: DRUG: Cabazitaxel, Docetaxel, Mitoxantrone or Satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the CiTop™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries
Status: COMPLETED
Conditions: Coronary Occlusion
Interventions: DEVICE: CiTop(tm) Guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Status: RECRUITING
Conditions: Crohn's Disease (CD)
Interventions: DRUG: Vedolizumab IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength and Muscle Activation of Runners Quadriceps After 8 Weeks of Intervention With Elastic Bandage
Status: UNKNOWN
Conditions: Muscle Strength
Interventions: DEVICE: Adhesive elastic bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms
Status: RECRUITING
Conditions: Cerebral Aneurysm
Interventions: PROCEDURE: Microsurgical clipping|PROCEDURE: Endovascular treatment|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of the App HeartBot on the Stress and Emotional Well-Being Over a 21-day Challenge
Status: COMPLETED
Conditions: Stress|Mental Health Wellness 1
Interventions: BEHAVIORAL: HeartBot App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Positive Effect of Ischemic Postconditioning During Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: postconditioning|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbon Nanoparticles vs Indocyanine Green
Status: UNKNOWN
Conditions: Number of Lymph Node Retrieved
Interventions: DRUG: injecting Carbon Nanoparticles Suspension|DRUG: Injecting indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Novel Single-puncture Triple Nerve Block; Sciatic, Obturator, Femoral Technique (SOFT), as a Sole Anesthesia for Knee Surgeries
Status: UNKNOWN
Conditions: Arthroscopic Knee Ligament Reconstruction
Interventions: PROCEDURE: new technique for lower limb nerve blocks using a single skin puncture (SOFT block)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DIETARY_SUPPLEMENT: MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention and Reversion of NAFLD in Obese Patients With Metabolic Syndrome by Mediterranean Diet and Physical Activity
Status: UNKNOWN
Conditions: Non Alcoholic Fatty Liver Disease
Interventions: OTHER: Physical activity and Mediterranean Diet (PA-MD)|OTHER: High meal frequency of Mediterranean Diet (HMF-MD)|OTHER: Control diet (CD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Advanced Glycation End Products
Status: WITHDRAWN
Conditions: SGLT-2 Inhibitors|Advanced Glycation End Products|Diabetes
Interventions: DRUG: empagliflozin|DRUG: linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutritional Supplementation With Turmeric on the Cognitive Performance of Subjects With Metabolic Syndrome
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: MERIVA® Tablets|OTHER: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Role of N-Acetylcysteine for Prevention of Cisplatin-induced Nephrotoxicity
Status: ACTIVE_NOT_RECRUITING
Conditions: Drug Toxicity
Interventions: DRUG: N-Acetylcysteine|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ulimorelin Study of Efficacy and Safety (ULISES 008)
Status: COMPLETED
Conditions: Gastrointestinal Dysmotility
Interventions: DRUG: Ulimorelin Intravenously (IV)|DRUG: Ulimorelin Invtravenously (IV)|DRUG: 5% dextrose in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary CT-Derived FFR-Guided Strategy Versus Medical Therapy
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Myocardial Ischaemia
Interventions: OTHER: ITS plus OMT|OTHER: OMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of HO/02/02 20µg vs. SoC (Aloe Vera) to Reduce Radiation Dermatitis
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: HO/02/02 20µg|OTHER: Aloe Vera Jel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture and Dry Needling in Peripheral Acute Fatigue Reduction
Status: COMPLETED
Conditions: Sedentary Lifestyle|Males
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: PROCEDURE: Tadalafil (PDE5i)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Hyperlipidemias|Hypertriglyceridemia|Dyslipidemias|Lipid Metabolism Disorders|Metabolic Diseases
Interventions: DRUG: CAT-2003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Application Research of Ultrasound Guided Puncture Stent Assisted Transperineal Prostate Biopsy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: OTHER: puncture stent-assisted transperineal prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination of Bevacizumab and Allogeneic NK Immunotherapy for Metastatic Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumour
Interventions: DRUG: Bevacizumab|BIOLOGICAL: NK immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma
Status: COMPLETED
Conditions: Clear-cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: Everolimus|DRUG: MLN0128|DRUG: MLN1117
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined and Simultaneous Approach for the Treatment of High-risk Gastric Varices Using B-RTO and EVO
Status: UNKNOWN
Conditions: Gastric Varices Bleeding|Gastric Varix
Interventions: PROCEDURE: balloon-occluded retrograde transvenous and endoscopic obliteration of high-risk gastric varices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department
Status: NOT_YET_RECRUITING
Conditions: Sickle-Cell Disease With Crisis
Interventions: DRUG: Parecoxib|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas
Status: RECRUITING
Conditions: Bone Sarcoma|Osteosarcoma|Ewing Sarcoma|Chondrosarcoma|Undifferentiated Pleomorphic Sarcoma|Leiomyosarcoma|Angiosarcoma
Interventions: DRUG: Treatment by Regorafenib|DRUG: Treatment by Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavior Cognitive Therapy on Fatigue Impact in MS Patients
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis|Fatigue|Cognitive Therapy
Interventions: BEHAVIORAL: Behavorial Cognitive Therapy (BCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE