pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Proactive Prescription-based Fluid Management vs Usual Care in Critically Ill Patients on Kidney Replacement Therapy
Status: RECRUITING
Conditions: Acute Kidney Injury|Kidney Replacement|Critical Illness
Interventions: OTHER: Protocol-based fluid management|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Pseudophakic Cystoid Macular Edema: Bromfenac 0.09% Versus Diclofenac Sodium 0.1% Versus Ketorolac Tromethamine 0.5%
Status: COMPLETED
Conditions: Acute Pseudophakic Cystoid Macular Edema
Interventions: DRUG: Bromfenac|DRUG: Ketorolac|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation?
Status: UNKNOWN
Conditions: Urinary Incontinence|Urinary Incontinence, Stress|Urination Disorders|Lower Urinary Tract Symptoms
Interventions: OTHER: Verbal instruction and Vaginal palpation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healing Touch and Health-Related Quality of Life in Women With Breast Cancer Receiving Radiation Therapy
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Sham treatment|BEHAVIORAL: Healing Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamic Study of Radium-223 in Men With Bone Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Bone Metastatic Castration-Resistant Prostate Cancer
Interventions: DEVICE: Biomarker analysis|DRUG: Administration of radium-223
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dapagliflozin on the Recurrence of Atrial Tachyarrhythmia in Patients Undergoing Catheter Ablation of Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation Recurrent|Catheter Ablation
Interventions: DRUG: Dapagliflozin 10 mg [Farxiga]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 557 in Adults With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: AMG 557
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DPC in Primary Molars.
Status: COMPLETED
Conditions: Direct Pulp Capping in Primary Teeth
Interventions: DRUG: Direct pulp capping with calcium hydroxide|DRUG: Direct pulp capping with MTA|DRUG: Direct pulp capping with Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 360 Degrees Virtual Reality-based Mirror Therapy for Stroke Patients
Status: COMPLETED
Conditions: Stroke|Stroke Rehabilitation|Mirror Movement Therapy
Interventions: PROCEDURE: 360 Degrees virtual reality-based mirror therapy|PROCEDURE: Traditional mirror therapy|PROCEDURE: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Bioequivalence Study to Qualify Manufacturing Site Transfer for Prazosin Hydrochloride Capsules
Status: COMPLETED
Conditions: Hypertension|Heart Failure
Interventions: DRUG: Prazosin HCl 2mg|DRUG: Prazosin HCl 1 mg|DRUG: Prazosin HCl 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Retrospective / Prospective Clinical Study of AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric Intraocular Lenses
Status: COMPLETED
Conditions: Cataract|Presbyopia|Corneal Astigmatism
Interventions: DEVICE: AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Plavix, Prasugrel and Drug Eluting Stents Pilot Trial
Status: UNKNOWN
Conditions: Coronary Artery Disease|Platelet Aggregation Inhibitors|PCI- Percutaneous Coronary Intervention
Interventions: DRUG: Loading Dose Arm|DRUG: Maintenance Dose Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Myocardial Performance Index and Epicardial Thickness in Cases With Idiopathic Polyhydramnios
Status: COMPLETED
Conditions: Fetal Diagnose|Fetal Cardiac Disorder
Interventions: DIAGNOSTIC_TEST: prenatal diagnose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sintilimab Combined With Bevacizumab Biosimilar for Potentially Resectable Intermediate HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab|DRUG: Bevacizumab Biosimilar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doll Therapy Efficacy for People With Dementia Living in Nursing Homes: a Randomized Single-blind Controlled Trial
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: Doll Therapy Intervention|BEHAVIORAL: active control group (SI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of the Efficacy of a Sensorimotor Approach After Maximum Three Sessions in Subjects With TMD With Hypertonia
Status: UNKNOWN
Conditions: Temporomandibular Disorder
Interventions: BEHAVIORAL: Sensorimotor education with a view to obtaining an optimal FWS further to the relaxation of the masticatory, lingual and labial system. Learning of mandibular micro-movements in 5 directions.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SPD476 (Mesalazine) Given Twice Daily (2.4 g/Day) vs SPD476 Given as a Single Dose (4.8 g/Day) in Subjects With Acute Mild to Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Delayed and extended release mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Traumatized Refugees -Stress Management Versus Cognitive Re-structuring
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: OTHER: Cognitive behavioural therapy (stress management)|OTHER: Cognitive Behavioural Therapy (cognitive restructuring)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Bupivacaine for Relief Postoperative Pain in Women Undergoing Laparoscopic Gynecologic Surgery
Status: COMPLETED
Conditions: Postoperative Pain Score
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Surgical Treatment of Impacted Femoral Neck Fracture in Patient 75 Years Old and Older
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Surgical Treatment for Impacted Femoral Neck Fracture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Site Infection Rate Between Primary, Delayed Primary and Vacuum Assisted Closures.
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: PROCEDURE: Primary Closure|PROCEDURE: Vacuum Assisted Closure|PROCEDURE: Delayed Primary Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Long-pulsed Nd:YAG, Amorolfine and Combination Treatment in Treating Non-dermatophyte Onychomycosis
Status: COMPLETED
Conditions: Non-dermatophyte Onychomycosis
Interventions: DEVICE: 1,064nm Long-pulsed Nd:YAG|DRUG: Amorolfine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sexual Steroids: Relationship Between Serum and Prostatic Tissue Level
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms|Prostate Hyperplasia
Interventions: BIOLOGICAL: steroids concentrations determination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Food Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxybutynin Chloride Extended-release Tablets 5 mg|DRUG: Ditropan XL® Tablets 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vermont Intervention: Effect on Joint Attention Skills Between Parents and Moderate/Late Preterm Infants in the First Year of Life
Status: UNKNOWN
Conditions: Premature Birth
Interventions: BEHAVIORAL: Mother Infant Transaction Program (MITP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Cross-cultural Adaptation and Validation of the CISS and the PWES Questionnaire in Patients With Hand Pathologies.
Status: RECRUITING
Conditions: Hand Injuries and Disorders
Interventions: OTHER: administration of F-CISS and F-PWES pre version|OTHER: administration of definitive version of F-CISS and F-PWES plus F-DASH, F-HFS and F-SF 36
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Trial of Infusional Gemcitabine in Combination With Carboplatin in Chemonaive Non-small Cell Carcinoma
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: carboplatin and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Bronchopulmonary Dysplasia
Interventions: DEVICE: CPAP and room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: BTA|DRUG: Placebo (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Cardiac MRI for Evaluation of Nonspecific Allograft Dysfunction
Status: COMPLETED
Conditions: Heart Transplant|Acute Graft Rejection|Chronic Graft Rejection
Interventions: DRUG: Regadenoson|DRUG: Gadolinium|PROCEDURE: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: "Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: Dipeptidyl Peptidase IV inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Functional Assessment of Intermediate Coronary Artery Stenosis Before and After Transcatheter Aortic Valve Implantation (TAVI) in Patients With Severe Symptomatic Aortic Valve Stenosis
Status: RECRUITING
Conditions: Coronary Artery Stenosis|Transcatheter Aortic Valve Implantation
Interventions: PROCEDURE: Assession of complete coronary physiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Music for Pain in the Waiting Room
Status: RECRUITING
Conditions: Pain, Acute
Interventions: BEHAVIORAL: Pain Coping Information|BEHAVIORAL: Lyrical Music|BEHAVIORAL: Instrumental Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a CF-specific CBT Intervention for Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Depression|Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a New Chemotherapy Agent to Treat Non Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: SH T00268C|DRUG: PTK787/ ZK 222584
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: Durvalumab|DRUG: Olaparib|DRUG: Placebo olaparib|DRUG: Durvalumab placebo|DRUG: Carboplatin+Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Misoprostol and Dinoprostone and Isonicotinic Acid Hydrazide Prior to Copper Intrauterine Device Insertion
Status: UNKNOWN
Conditions: IUCD Complication
Interventions: DRUG: Isonicotinic Acid Hydrazide|DRUG: dinoprostine|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Clinical Study to Evaluate the Narrowing of the Aorto-iliac Arteries While Using Gadodiamide
Status: COMPLETED
Conditions: Aorto-iliac Stenosis|Arterial Occlusive Diseases
Interventions: DRUG: Gadodiamide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Conbercept for Diabetic Macular Edema Combined With Severe Non-proliferative Diabetic Retinopathy
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asian Phase II Study of INC424 in Patients With Primary Myelofibrosis (MF), Post-PV MF or Post-ET MF
Status: COMPLETED
Conditions: Primary Myelofibrosis (MF)|Post-Polycythemia Vera (PV) MF|Post-Essential Thrombocythemia (ET) MF
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epirubicin, Docetaxel, and Pegfilgrastim in Treating Women With Locally Advanced or Inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: docetaxel|DRUG: epirubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
Status: UNKNOWN
Conditions: Kidney Stone
Interventions: PROCEDURE: Super-mini percutaneous nephrolithotomy (SMP)|PROCEDURE: Extracorporeal Shock Wave Lithotripsy (ESWL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irinotecan, Temozolomide and Bevacizumab in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Newly Diagnosed Patients With Desmoplastic Small Round Cell Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma|Desmoplastic Small Round Cell Tumor (DSRCT)
Interventions: DRUG: irinotecan, temozolomide, and bevacizumab incorporated into an existing schedule of high dose alkylator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Preference of Taclonex Ointment to Taclonex Scalp Suspension in Adult Subjects With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Taclonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Maintenance of Vitamin D Level by UVB Radiation
Status: COMPLETED
Conditions: Vitamin D Status
Interventions: RADIATION: Broadband UVB|RADIATION: Broadband UVB|RADIATION: Broadband UVB|RADIATION: Broadband UVB|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temperament Dimensions and Awakening Salivary Cortisol Levels in ADHD.
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIAGNOSTIC_TEST: Swanson, Noolan and Phelham - IV edition (SNAP-IV); Conners' Parent Rating Scales (CPRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis
Status: RECRUITING
Conditions: Diffuse Cutaneous Systemic Sclerosis|Sclerosis, Systemic
Interventions: DRUG: HZN-825 BID|DRUG: Placebo|DRUG: HZN-825 QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: OROS Hydromorphone HCI SR (slow release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Empagliflozin in Hemodialysis
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Clinical Outcomes Between GentleWave® and Biolase®
Status: ACTIVE_NOT_RECRUITING
Conditions: Endodontic Disease|Periapical Diseases|Periapical Periodontitis|Root Canal Infection
Interventions: DEVICE: Irrisafe ip|DEVICE: GentleWave System|DEVICE: Waterlase iPlus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based CBT for Recent Veterans Experiencing Problems With Trauma Symptoms or Alcohol/Drug Use
Status: UNKNOWN
Conditions: Post-Traumatic Stress Symptoms|Problematic Use of Alcohol or Other Drugs
Interventions: BEHAVIORAL: Web-based Cognitive Behavioral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Frequency Domain Imaging (OFDI) Assessed Strut Coverage of New Terumo DES
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TCD-10023 drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Damage and Atherosclerosis in Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Insulin Resistance|Endothelial Function|Oxidative Stress
Interventions: DEVICE: CPAP machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Infusion of White Blood Cells in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: BI 671800 ED in Steroid-naive Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BI 671800|DRUG: Fluticasone propionate placebo|DRUG: Fluticasone propionate|DRUG: BI 671800 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Vasomotor Symptoms|Menopausal Symptoms
Interventions: DRUG: Estetrol oral tablet|DRUG: Placebo oral tablet|DRUG: Progesterone oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Acute Leukemia|Chronic Leukemia|Lymphoproliferative Disease|Myeloproliferative Disease|Immunodeficiency
Interventions: OTHER: Analyze the pharmacokinetics of busulfan for transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety of Tezepelumab in Japanese Subjects With Inadequately Controlled Severe Asthma
Status: COMPLETED
Conditions: Severe Asthma
Interventions: DRUG: Biological: Experimental: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
Status: RECRUITING
Conditions: Epilepsies, Myoclonic
Interventions: DRUG: Placebo|DRUG: Lorcaserin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents
Status: COMPLETED
Conditions: Pain|Nausea|Pruritus
Interventions: DRUG: naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Types of Concurrent Training in Functional Performance and Cognitive Function of Older Adults
Status: RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: Traditional concurrent training|BEHAVIORAL: Concurrent training consisting of strength training combined with dance classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Ferrisat vs Placebo in Anemia Associated to Inflammatory Bowel Disease During Anti-TNF Therapy
Status: TERMINATED
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: FERRISAT|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Citalopram on Motivation
Status: COMPLETED
Conditions: Normal Volunteers
Interventions: DRUG: Citalopram 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Tolerability of Omalizumab in Patients With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Omalizumab|DRUG: Omalizumab|DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Hospital-based Postnatal Parent Education Intervention About Infant Immunizations
Status: UNKNOWN
Conditions: Postpartum Women
Interventions: BEHAVIORAL: Low intensity intervention|BEHAVIORAL: High intensity intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Myofascial Arm Pull With and Without Active Release Technique in Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: OTHER: Myofascial Arm Pull and Active Release Technique|OTHER: Myofacial Arm Pull
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain
Status: UNKNOWN
Conditions: Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naive
Interventions: DRUG: 2.5ug/h transdermal fentanyl|DRUG: Oral immediate-released morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Multi-Organ Metabolism and Perfusion in NAFLD by Total Body Dynamic PET Scan on EXPLORER
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis (NASH)
Interventions: RADIATION: Positron Emission Tomography (PET) on EXPLORER|DIAGNOSTIC_TEST: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Echocardiogram and Electrocardiogram|DIAGNOSTIC_TEST: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Piloting a Biofeedback Intervention for Adolescents With Overweight and a History of Adverse Childhood Experiences
Status: WITHDRAWN
Conditions: Obesity, Adolescent
Interventions: BEHAVIORAL: Biofeedback|OTHER: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Oxytocin Infusion on Blood Loss During Abdominal Myomectomy
Status: COMPLETED
Conditions: Myomectomy
Interventions: DRUG: Oxytocin|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Interest of the Temporary Urethral Stent Allium " Bulbar Urethral Stent " in the Treatment of Detrusor Sphincter Dyssynergia
Status: COMPLETED
Conditions: Detrusor Striated Sphincter Dyssynergia (DSSD)
Interventions: DEVICE: Allium " Bulbar Urethral Stent " (BUS) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHP-BV Followed by Consolidation With High-dose Therapy / ASCT as Frontline Treatment of Patients With EATL Type 1.
Status: COMPLETED
Conditions: Enteropathy Associated T-cell Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Socket Fit in Female and Male Veterans With Transtibial and Transfemoral Amputation
Status: RECRUITING
Conditions: Transtibial Amputation|Transfemoral Amputation
Interventions: DEVICE: Conventional prosthetic socket|DEVICE: Adjustable Quatro socket
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Osteochondroma|Ollier Disease|Osteogenesis Imperfecta
Interventions: OTHER: 5-day sailing activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 Infection
Status: UNKNOWN
Conditions: Respiratory Failure|Ventilatory Failure|COVID-19|Pneumonia|ARDS, Human
Interventions: DEVICE: AirGo Respiratory Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient Preference and Satisfaction With Insulin Glargine (Lantus) Solostar Pen vs Conventional Vial-Syringe Method of Lantus Injection Therapy in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Fibromyalgia and CFS With Ribose, Ashwagandha, Rhodiola, Licorice, Schisandra and Green Tea Extract
Status: UNKNOWN
Conditions: Fibromyalgia|CFS
Interventions: DIETARY_SUPPLEMENT: Smart Energy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of TheraFill® Versus KOKEN for 3 Months on Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: KOKEN|DEVICE: Atelocollagen Filler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622
Status: COMPLETED
Conditions: Hypereosinophilic Syndrome
Interventions: DRUG: Mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Oligodendroglioma|Anaplastic Oligodendroglioma
Interventions: DRUG: RRx-001 dose escalation with TMZ + RT|RADIATION: Radiation|DRUG: Fixed dose Temozolomide (75 mg/m2)|DRUG: TMZ Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis|NASH|Exercise|Liver
Interventions: BEHAVIORAL: Exercise Intervention with use of El-Fit App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: R2P Field Test of the EMS LiftKit: Validating Usability, Usefulness, Desirability, and Effects on Musculoskeletal Injuries in EMS Providers
Status: ENROLLING_BY_INVITATION
Conditions: Musculoskeletal Disorder
Interventions: OTHER: LiftKit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Three Anxiolytic Drugs Used in Third Molar Surgery
Status: COMPLETED
Conditions: Dental Anxiety|Impacted Third Molar Tooth
Interventions: DRUG: Mulungu|DRUG: Placebo|DRUG: Passiflora incarnata|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Therapy Based on Biological Specificity of Acupoints for Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRIs|PROCEDURE: acupuncture (strong reaction acupoints)|PROCEDURE: acupuncture (weak reaction acupoints)|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PDL-1 Inhibition and Focal Sensitizing Radiotherapy in Recurrent Ovarian/Primary Peritoneal/Fallopian Tube Cancers.
Status: UNKNOWN
Conditions: Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer
Interventions: RADIATION: Focal radiotherapy|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Pharmacist-delivered Discharge and Follow-up Intervention for Patients With Acute Coronary Syndromes in Qatar
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: BEHAVIORAL: Structured intervention at discharge and tailored follow up post discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Video Capsule Endoscopy (VCE) Comparison Study
Status: COMPLETED
Conditions: Bleeding|Anemia|Diarrhea
Interventions: PROCEDURE: Video capsule endoscopy (VCE)|DEVICE: MiroCam|DEVICE: Enteropro EndoCapsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Liraglutide on Body Weight in Obese Subjects or Overweight Subjects With Co-morbidities
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IMM0306 in Patients With Relapsed or Refractory CD20-positive B-cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: CD20-positive B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: IMM0306
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Seniors COvid-19 Pandemic and Exercise Study
Status: COMPLETED
Conditions: Well-Being (Psychological Flourishing)|Depression|Quality of Life|Loneliness|Physical Activity|Social Identification|Physical Health
Interventions: BEHAVIORAL: Virtual Group Intervention|BEHAVIORAL: Personal Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Broad Spectrum HPV Vaccine Dose Escalation Study (V502-002)
Status: COMPLETED
Conditions: Human Papilloma Virus|Cervical Cancer|Vulvar Cancer|Vaginal Cancer|Genital Warts
Interventions: BIOLOGICAL: Octavalent HPV with 15 mcg IMX / AAHS|BIOLOGICAL: Octavalent HPV with 30 mcg IMX / AAHS|BIOLOGICAL: Octavalent HPV with 60 mcg IMX / AAHS|BIOLOGICAL: Octavalent HPV with 120 mcg IMX / AAHS|BIOLOGICAL: Comparator: Quadrivalent HPV Vaccine (qHPV), (GARDASIL™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Kinesio Taping Applications on Pain, Neck Awareness and Functionality in Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Physiotherapy|Kinesiotape|Chronic Neck Pain
Interventions: OTHER: Traditional Physiotherapy + Placebo Kinesio Tape|OTHER: Traditional Physiotherapy + Kinesio Tape Treatment with Inhibition Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Loss in Women With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: Testosterone|DRUG: Actonel (risedronate)|DRUG: Placebo Actonel (risedronate)|DRUG: Placebo testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of a Novel Negative Pressure Wound Therapy Glove for Hand Injuries
Status: NOT_YET_RECRUITING
Conditions: Hand Injuries
Interventions: DEVICE: ReHeal glove with Negative Pressure Wound Therapy (NPWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment
Status: COMPLETED
Conditions: Oral Cavity Cancer
Interventions: DRUG: PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Of The Relationship Between Temporomandibular Disorder With Posture And Pedobarographic Analysis
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Postural Analysis|OTHER: plantar pressure analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate the Efficacy and Safety of Lusutrombopag (S-888711) Tablets Administered to Adults With Immune Thrombocytopenia (ITP)
Status: TERMINATED
Conditions: Immune Thrombocytopenia (ITP)
Interventions: DRUG: Placebo|DRUG: Lusutrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Randomized, Prospective Double-Blind, Single-Center, Placebo-controlled Study to Evaluate Safety, Tolerability, Target Engagement, and Efficacy of PrimeC in Patients With Mild to Moderate Alzheimer's Disease.
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: PrimeC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab in Patients With dMMR and/or MSI Metastatic Colorectal Cancer Resistant to Anti-PD1 Monotherapy
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer Stage III
Interventions: DRUG: FOLFOXIRI+Cetuximab regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexmedetomidine for Treatment of Shivering During Cesarean Section Under Neuraxial Anesthesia
Status: COMPLETED
Conditions: Tremor
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Remimazolam on the Incidence of Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Status: NOT_YET_RECRUITING
Conditions: Hypoxia|Hysteroscopy|Overweight or Obesity
Interventions: DRUG: remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Selegiline Plus Docetaxel for the Treatment of Metastatic, Castrate-resistant Prostate Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: Selegiline|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea
Status: RECRUITING
Conditions: Dysmenorrhea|Prolotherapy
Interventions: PROCEDURE: Posterior tibial nerve neuroprolotherapy|DRUG: Acetaminophen 500Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Optilene® Mesh Elastic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nutraceutical Supplement With Vegan Botanicals in Females With Self-Perceived Thinning Hair
Status: COMPLETED
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Nutrafol Vegan Women's Hair Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis
Status: TERMINATED
Conditions: Uremic Pruritus
Interventions: DRUG: Nalfurafine hydrochloride(MT-9938) 2.5μg|DRUG: Nalfurafine hydrochloride(MT-9938) 5μg|DRUG: Nalfurafine hydrochloride(MT-9938) 10μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Counseling in Improving Communication and Quality of Life in Spouses and Breast Cancer Patients
Status: COMPLETED
Conditions: Anxiety Disorder|Depression|Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ|Psychosocial Effects of Cancer and Its Treatment|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: educational intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: psychosocial support for caregiver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Tolerability of Clopidogrel Resinate and Clopidogrel Bisulfate in Patients With Coronary Heart Disease (CHD) or CHD Equivalents
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: aspirin + pregrel (Clopidogrel resinate)|DRUG: aspirin + placebo|DRUG: aspirin + plavix (Clopidogrel bisulfate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months
Status: COMPLETED
Conditions: Obesity|Water; Lack of|Breast Feeding|Tooth Erosion|Dental Plaque|Infant Obesity|Feeding Behavior|Mother-Child Relations|Dietary Habits|Dental Caries
Interventions: BEHAVIORAL: Family Spirit Nurture (FSN)|OTHER: Control Program|OTHER: Water Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis
Interventions: DRUG: green propolis mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advancing Lung Cancer Screening: Artificial Intelligence, Multimodal Imaging and Cutting-Edge Technologies for Early Detection and Characterization
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer Screening
Interventions: PROCEDURE: LDCT scan and simultaneous [18F]FDG PET/CT on new-generation long axial field of view scanner|PROCEDURE: LDTC only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis
Status: TERMINATED
Conditions: Diverticulitis
Interventions: DRUG: Mesalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prognosis Impact of NSVTs After an AMI (TeVeO Study).
Status: ACTIVE_NOT_RECRUITING
Conditions: Death, Sudden|Ventricular Tachycardia|Implantable Defibrillator User|Myocardial Infarction|Myocardial Dysfunction
Interventions: DEVICE: Implantable Loop Recorder implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy Regimens in Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypomemylating Agents Combination With eDC Therapy for Elderly Patients With Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Dendritic Cell|Hypomethylating Agents|Immunotherapy
Interventions: BIOLOGICAL: DC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION