pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gemcitabine With or Without Sorafenib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Project Q Pilot: Smoking Cessation for Light Smokers
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: BEHAVIORAL: Cognitive behavioral cessation counseling|BEHAVIORAL: Counseling and placebo drug intervention|DRUG: Counseling and active drug intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
Status: COMPLETED
Conditions: Anxiety|Depression|Stress
Interventions: OTHER: SoundMind App|OTHER: Spotify Playlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multicenter Phase 2 Study of Subcutaneous Isatuximab Plus Bortezomib, Lenalidomide and Dexamethasone in the Treatment of Newly Diagnosed Transplant Ineligible Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Myeloma Multiple|Myeloma
Interventions: OTHER: Drug and medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flash Glucose Monitoring in Gestational Diabetes Mellitus: Study Protocol for a Randomized Controlled Trial
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DEVICE: Flash Glucose Monitoring|DEVICE: Self-Monitoring of Blood Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Family Bridge Program
Status: NOT_YET_RECRUITING
Conditions: Healthcare Inequities|General Pediatric Medical Conditions|Healthcare System Navigation|Patient-provider Communication
Interventions: BEHAVIORAL: Family Bridge Program|BEHAVIORAL: Care as usual - resources only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clonal Hematopoiesis of Immunological Significance
Status: NOT_YET_RECRUITING
Conditions: Immune System Diseases|Autoimmune Diseases|Inflammation|Autoinflammatory Diseases|Vexas Syndrome|Hematopoiesis Clonal|Clonal Hematopoiesis of Indeterminate Potential|Hematologic Diseases|Myelodysplastic-Myeloproliferative Diseases|Leukemia Myelomonocytic Chronic|Myelodysplastic Syndromes|Myeloproliferative Disorders|Lymphoproliferative Disorders|Lymphoma|Leukemia|Monoclonal Gammopathy of Undetermined Significance
Interventions: OTHER: observational cohort study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Anti-PD-1/CTLA-4 Bispecific AK104 Alone or in Combination With Lenvatinib in Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: AK104 lenvatinib|BIOLOGICAL: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Papillae Tunneling Techniques in the Treatment of Isolated Intrabony Defects
Status: COMPLETED
Conditions: Periodontitis Complex|Xenograft Model
Interventions: DEVICE: Xenogenic bone graft material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pericapsular Nerve Group (PENG) Block for Perioperative Analgesia in Geriatric Patients With Hip Fractures
Status: RECRUITING
Conditions: Hip Fractures
Interventions: PROCEDURE: pericapsular nerve group (PENG) block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nasal Brushing for the Diagnosis and Understanding of Telomeropathies
Status: RECRUITING
Conditions: Telomere Disease|Telomere Shortening
Interventions: DIAGNOSTIC_TEST: Nasal brushing|DIAGNOSTIC_TEST: Sniffin' Sticks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Study of Surufatinib in Treating Advanced Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Surufatinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Biodistribution, Safety, and Tolerability of a Microdose of Radiolabeled BIIB080 Co-administered With BIIB080 in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: [89Zr]Zr-DFO-BIIB080|DRUG: BIIB080
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose NOAC Versus GDMT After LAAO
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban 15mg|DRUG: Aspirin 100mg|DRUG: Clopidogrel 75mg|DRUG: Rivaroxaban 10mg|DRUG: Rivaroxaban 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Estradiol Pretreatment in Labour Induction With Misoprostol
Status: COMPLETED
Conditions: Failed Induction of Labor
Interventions: DRUG: Estradiol|DRUG: Placebo|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Safety, Tolerability And Pharmacokinetics Of Single And Multiple Doses Of Compound PF-06823859
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-06823859|DRUG: Placebo injection SC/IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Study of Temperature-controlled and Bipolar Radiofrequency for Inferior Turbinate Reduction
Status: COMPLETED
Conditions: Patients With Chronic Rhinitis Who Failed Medical Treatment
Interventions: PROCEDURE: Temperature-controlled RF|DEVICE: Bipolar RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Cancer|Gastric Cancer|Gastroesophageal-junction Cancer|Pancreatic Cancer
Interventions: DRUG: TST001|DRUG: Nivolumab Injection [Opdivo]|DRUG: mFOLFOX6|DRUG: Gemcitabine|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study)
Status: COMPLETED
Conditions: Left Ventricular Dysfunction
Interventions: BIOLOGICAL: Adult stem cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Biosynthetic Growth Hormone and/or Ethinyl Estradiol on Adult Height in Patients With Turner Syndrome
Status: COMPLETED
Conditions: Gonadal Dysgenesis|Turner's Syndrome
Interventions: DRUG: Growth Hormone (Humatrope)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of 532nm Laser Subthreshold Panretinal Photocoagulation for Severe NPDR
Status: UNKNOWN
Conditions: Severe Non-proliferative Diabetic Retinopathy
Interventions: RADIATION: T-PRP|RADIATION: S-PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COZMOS:Phase I/Ib Trial of Combined 5'Azacitidine and Carboplatin for Recurrent/Refractory Pediatric Brain/Solid Tumors
Status: COMPLETED
Conditions: Recurrent Childhood CNS Tumor|Ependymoma, Recurrent Childhood|Childhood Solid Tumor
Interventions: DRUG: 5 Azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection for Remnant Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Indocyanine Green Tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients
Status: TERMINATED
Conditions: Chronic Pain
Interventions: DRUG: Lidocaine infusion|DRUG: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Moderate Depressive Disorder With Cheek Acupuncture
Status: NOT_YET_RECRUITING
Conditions: Acupuncture|Depression
Interventions: OTHER: cheek acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on HRQOL and Cost-effectiveness Analysis in Management of Patients With <2cm Thyroid Nodules
Status: COMPLETED
Conditions: Thyroid Nodules
Interventions: OTHER: Fine Needle Aspiration Cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study Between Nicorandil and Nifedipine for the Treatment of Preterm Labour
Status: UNKNOWN
Conditions: Preterm Labor With Preterm Delivery
Interventions: DRUG: Potassium Channel Opener|DRUG: Calcium channel blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment.
Status: COMPLETED
Conditions: Peri-Implantitis|Periodontal Diseases
Interventions: PROCEDURE: Surgical anti-infective therapy|PROCEDURE: Periodontal treatment|PROCEDURE: Oral Hygiene Instruction|DRUG: Triclosan toothpaste|DRUG: Fluoride toothpaste|PROCEDURE: Regular maintenance program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Safety and Tolerability of Tacrolimus Extended-Release (Astagraf XL) in Human Leukocyte Antigen (HLA) Sensitized Kidney Transplant Recipients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Tacrolimus Extended-Release Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Older Patients With Type2 Diabetes Insufficiently Controlled on Their Current Antidiabetic Medications
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Glargine (HOE901 - U300)|DRUG: Insulin Glargine (HOE901 - U100)|DRUG: Background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: Rosuvastatin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Worms for Immune Regulation of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Hookworm larvae|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity
Status: COMPLETED
Conditions: Rhinitis, Allergic, Nonseasonal
Interventions: PROCEDURE: Nasal irritation thresholds and irritant provocation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose:
Clinical trial: A Randomized Phase 1 of of MZE001 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MZE001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IASO-782 in Autoimmune Hematological Diseases
Status: NOT_YET_RECRUITING
Conditions: Autoimmune Thrombocytopenia|Warm Autoimmune Haemolytic Anaemia
Interventions: DRUG: IASO-782 injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device
Status: NOT_YET_RECRUITING
Conditions: Acute-On-Chronic Liver Failure|Anticoagulant Adverse Reaction|Sarcopenia|Ultrasonography
Interventions: DEVICE: CytoSorb
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of Ergoferon in the Treatment of Acute Respiratory Viral Infections in Children
Status: COMPLETED
Conditions: Acute Respiratory Viral Infections
Interventions: DRUG: Ergoferon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosomatic Effects of Implantable Cardioverter Defibrillator With Home Monitoring Function (QUANTUM)
Status: COMPLETED
Conditions: Arrhythmia|Quality of Life
Interventions: DEVICE: HM on|DEVICE: HM Off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Tolerability of MK-0517 in Healthy Subjects (MK-0517-012)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting|Postoperative Nausea and Vomiting
Interventions: DRUG: 90 mg MK-0517 (PS80)|DRUG: 100 mg MK-0517 (PS80)|DRUG: 100 MK-0517 (PS80) + 2 mg midazolam|DRUG: 115 mg MK-0517 (PS80)|DRUG: 150 mg MK-0517 (PS80)|DRUG: 40 mg MK-0517 (non-PS80)|DRUG: 100 mg MK-0517 (non-PS80)|DRUG: 150 mg MK-0517 (Non-PS80)|DRUG: Placebo|DRUG: 40 mg Aprepitant|DRUG: 125 mg Aprepitant|DRUG: 2 mg Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ripretinib in Combination With Binimetinib in Patients With Gastrointestinal Stromal Tumor (GIST)
Status: WITHDRAWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Ripretinib|DRUG: binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difficult Intravenous Access in Pediatric Patients: Paramedical Care Using Ultrasound Guidance
Status: NOT_YET_RECRUITING
Conditions: Catheter Related Complication
Interventions: PROCEDURE: peripheral intravenous catheterization performed with ultrasound guidance by a trained nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Fc-Optimized Anti-CD19 Antibody (MOR00208) to Treat B-cell Acute Lymphoblastic Leukemia(B-ALL)
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: MOR00208 (formerly Xmab5574)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension
Status: RECRUITING
Conditions: Haematological Malignancy|Hypogammaglobulinemia
Interventions: DRUG: trimethoprim-sulfamethoxazole (co-trimoxazole)|DRUG: amoxycillin/clavulanic acid and ciprofloxacin|DRUG: Immunoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Random Biopsies in Patients With Inflammatory Bowel Disease
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: Biopsy strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nitrous TRD Bipolar Depression
Status: TERMINATED
Conditions: Treatment- Resistant Bipolar Disorder|Bipolar Disorder|Bipolar Depressive Disorder
Interventions: DRUG: Nitrous Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Pharmacokinetics and Pharmacodynamics Study With Mepolizumab in Asthma Patients With Elevated Eosinophils
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly
Status: RECRUITING
Conditions: Glioblastoma Multiforme, Adult|Glioblastoma, IDH-mutant
Interventions: RADIATION: Dose escalation + Reduced Margin Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Measurement of Handgrip Strength on Physical Activity Level for Patients With Diabetes Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Physical Activity|Muscular Weakness
Interventions: DEVICE: Handgrip strength measurement|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug
Status: COMPLETED
Conditions: Obesity|Hepatic Insufficiency
Interventions: DRUG: CP-945,598|DRUG: CP-945,598|DRUG: CP-945,598
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
Status: COMPLETED
Conditions: Medical; Abortion, Fetus
Interventions: PROCEDURE: Programmed Intermittent Epidural Bolus|PROCEDURE: Continuous Epidural Infusion|PROCEDURE: Procedure of interruption of pregnancy|DRUG: Drug used for analgesia procedures|DEVICE: Pump for programmed intermittent bolus.|DEVICE: Pump for continuous epidural infusion.|DRUG: Drug used for termination of pregnancy procedure.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Xylitol Nasal Irrigation After Functional Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis|Postoperative Care
Interventions: DRUG: Xylitol Powder|DRUG: Salt Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Betamethasone Gel and Lidocaine Jelly on Sore Throat, Cough and Hoarseness of
Status: COMPLETED
Conditions: Sore Throat|Cough
Interventions: DRUG: betamethasone gel|DRUG: lidocaine jelly|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adrenergic System in Islet Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1diabetes|Hypoglycemia|Hypoglycemia Unawareness|Islet Cell Transplantation
Interventions: DRUG: Phentolamine|DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture
Status: COMPLETED
Conditions: Isthmocele|Uterine Scar Defects|Cesarean Section Complications|Uterine Niche
Interventions: PROCEDURE: Clinical and ultrasonographic assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Maternal Hypothermia After Scheduled Caesarean Section Using Active Intravenous Warming
Status: UNKNOWN
Conditions: Postoperative Hypothermia
Interventions: DEVICE: enFlow® IV fluid warmer and from July 2019 Fluido®Compact IV fluid warmer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Whole Body Vibration and BOSU Ball in Spastic Cerebral Palsy
Status: RECRUITING
Conditions: Spastic Cerebral Palsy
Interventions: DEVICE: Whole Body Vibration|DEVICE: BOSU ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Efficacy of Etoricoxib in Female Patients With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DRUG: etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Post-stroke Shoulder Pain
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|DEVICE: Sham Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors|Locally Advanced or Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: XZP-5955 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Contraception After First Trimester Abortion - Effects on Quality of Life and Risk of Repeat Abortion.
Status: COMPLETED
Conditions: Contraception
Interventions: DEVICE: Immediate intrauterine contraception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Flonase® Allergy Relief in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: olopatadine hydrochloride ophthalmic solution 0.7%)|DRUG: Fluticasone Propionate|DRUG: Tears Naturale|DRUG: Saline nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Necessity of Using Pleural Drainage Tubes After IMA Harvesting During Cardiac Surgery
Status: COMPLETED
Conditions: Pleural Effusions Post Coronary Artery Bypass Graft
Interventions: PROCEDURE: No Pleural Chest Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality Glasses in The Arteriovenous Fistule Cannulation Processon Paın and Patient Satisfaction
Status: COMPLETED
Conditions: Arteriovenous Fistula
Interventions: OTHER: Study Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Routine Use of Nasopharyngeal Airway in the Setting of Monitored Anesthesia Care During Gastrointestinal Endoscopy
Status: COMPLETED
Conditions: Monitored Anesthesia Care|Gastrointestinal Endoscopy|Nasopharyngeal Airway
Interventions: DEVICE: Nasopharyngeal airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPARC1316
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SPARC1316 Dose 1|DRUG: Placebo|DRUG: SPARC1316 Dose 2|DRUG: SPARC1316 Dose 3|DRUG: SPARC1316 Dose 4|DRUG: SPARC1316 Dose 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Silodosin Singly or Combined With Ningmitai Capsules in the Treatment of Benign Prostatic Hyperplasia
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Interventions: DRUG: Silodosin Capsules|DRUG: Ningmitai capsule|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Medical Devices for Labor Induction After Previous C-section
Status: RECRUITING
Conditions: Delivery, Obstetric|Cesarean Section|Obstetric Delivery
Interventions: DEVICE: Double ballon device, Cook|DEVICE: Hygroscopic cervix dilators, Dilapan-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Saliva Testing for High-Risk Human Papillomavirus Infection Oral Cavity and Pharynx Cancer
Status: NOT_YET_RECRUITING
Conditions: Oropharyngeal Squamous Cell Carcinoma|Human Papillomavirus Infection
Interventions: GENETIC: Pre-Radiation Dental Evaluation/Sample Collection|OTHER: Pre-Study Visit|GENETIC: Oral Medicine Consultation Visit/Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Placebo Controlled Trial With Etoricoxib That is Taken to Prevent the Yom Kippur Headache
Status: UNKNOWN
Conditions: Headache
Interventions: DRUG: etoricoxib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Drug-Drug Interaction Study: ASP2151 and Ciclosporin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ASP2151 400mg + 100mg ciclosporin|DRUG: ASP2151 1200mg + 100mg ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can Technology-Assisted Toilets Improve Hygiene and Independence in Geriatric Rehabilitation? A Cohort Study
Status: UNKNOWN
Conditions: Geriatric Rehabilitation
Interventions: DEVICE: Technology-Assisted Toileting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Tapering or Standard Steroids for Nephrotic Syndrome
Status: UNKNOWN
Conditions: Nephrotic Syndrome
Interventions: DRUG: long term tapering of prednisolone|DRUG: standard prednisolone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for Treating Submacular Vascularized Pigment Epithelial Detachments
Status: COMPLETED
Conditions: Retinal Pigment Epithelial Detachment
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab|DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Decitabine in Myelodysplastic Syndrome Post Azacytidine Failure
Status: TERMINATED
Conditions: Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Replacing Lantus With Basalin on the Glycemic Variation in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: DRUG: Basalin to Lantus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-Escalation, Safety, Pharmacokinetics Study of Cabazitaxel With Gemcitabine In Patients With Solid Tumor
Status: TERMINATED
Conditions: Neoplasms, Malignant
Interventions: DRUG: cabazitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosimetry/Validation Study of 131Iodine-Anti B1 (Murine) Radioimmunotherapy for Chemotherapy Refractory Low Grade B Cell Lymphomas and Low Grade Lymphomas That Have Transformed to Higher Grade Histologies
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Tositumomab (Anti-B1 Antibody) and Iodine-131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Patients With Spinal Cord Injury, Polytrauma and Burn Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Polytrauma|Burn Injury
Interventions: DRUG: Placebo|DRUG: Oxycodone|OTHER: Essential Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Rehabilitation Before Lung Cancer Resection
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: education|PROCEDURE: rehabilitation|DEVICE: pedometer|OTHER: education|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain
Status: RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Cold intrapulpal anesthesia|PROCEDURE: Room temperature intrapulpal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Center, Open Label, Study of Preparation H on Erythema in Relapsing MS Patients Treated With PLEGRIDY
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: OTHER: No Treatment Arm|DRUG: Topical Preparation H arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Next Science Antimicrobial Mouth Rinse Study
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: COMBINATION_PRODUCT: Next Science OTC Oral Rinse with Essential Oils|COMBINATION_PRODUCT: OTC Oral Rinse Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Interventions: DRUG: ABP 234|DRUG: Pembrolizumab (US)|DRUG: Pembrolizumab (EU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cladribine, Cytarabine and Idarubicin in Patients With Relapsed Acute Myelocytic Leukemia (AML)
Status: UNKNOWN
Conditions: Leukemia, Myelocytic, Acute
Interventions: DRUG: cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Health Link: Connecting Patients With Services
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: BEHAVIORAL: Strengths Based Case Management|BEHAVIORAL: Motivational Enhancement Therapy|BEHAVIORAL: Brief Informational Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen Planus
Status: COMPLETED
Conditions: Cutaneous Lichen Planus
Interventions: DRUG: Baricitinib (LY3009104) 2 mg|DRUG: Baricitinib (LY3009104) 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation Clinical Results of Coronally Advanced Flap With Platelet Rich Fibrin
Status: COMPLETED
Conditions: Root Coverage
Interventions: PROCEDURE: Platelet rich fibrin and coronally advanced flap|PROCEDURE: Connective tissue graft and coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Pyridostigmine in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Pyridostigmine Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Purified Isoflavones in Prostate Cancer: Comparing Safety, Effectiveness
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Purified isoflavones|DRUG: Methyl cellulose blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate LUTS and Complications Between Indwelling Catheter and Temporary Prostatic Stent in Patients Undergoing Minimally Invasive Procedures for the Treatment of Localized Prostate Cancer or Benign Prostatic Hyperplasia (HERMES)
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms|Prostatic Hyperplasia|Prostatic Cancer|Urinary Retention
Interventions: DEVICE: Temporary prostatic stent (Exime®)|DEVICE: Indwelling catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PGT121|BIOLOGICAL: PGDM1400|BIOLOGICAL: 10-1074|BIOLOGICAL: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ocular Effects of Scleral Lens Wear on Dry Eye Patients
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Hydra-PEG|DEVICE: Uncoated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of OMTX705, Monotherapy and Pembrolizumab-combined, in Subjects With Advanced Solid Tumors.
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: OMTX705|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mirabegron and Physiological Function in Cold Environments
Status: COMPLETED
Conditions: Resting Energy Expenditure|Thermogenesis|Brown Adipose Tissue
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Activity and Tolerability of Lopinavir/Ritonavir and Lamivudine Bitherapy in HIV Patients With Viral Suppression
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: antiretroviral treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Stage III Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx
Interventions: DRUG: vorinostat|DRUG: cisplatin|RADIATION: radiation therapy|PROCEDURE: Correlative Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Associative Plasticity for ALS
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Spinal Cord Associative Plasticity (SCAP)|PROCEDURE: Upper extremity task-oriented exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: OPS-2071 Single and Multiple Dose Study to Investigate PK and PD Profile in Healthy Korean Male Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Part1 : OPS-2071|DRUG: Part1 : Placebo of OPS-2071|DRUG: Part2 : OPS-2071|DRUG: Part2 : Placebo of OPS-2071
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tranexamic Acid vs Fractional CO2 Laser in Post-acne Hyperpigmentation
Status: UNKNOWN
Conditions: Post Inflammatory Hyperpigmentation
Interventions: DRUG: Tranexamic Acid|DEVICE: Fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Autologous Mesenchymal Bone Marrow Stem Cells in Active & Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: syngeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: PA-824|DRUG: PA-824|DRUG: PA-824|DRUG: Rifafour e-275 mg|DRUG: PA-824
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of Aramchol in Subjects With NASH (ARMOR)
Status: SUSPENDED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: Aramchol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olfaction Disorders in Patients Included in The Trauma Brain Injury (TBI) Database at Trondheim University Hospital
Status: COMPLETED
Conditions: Brain Injuries|Olfaction Disorders
Interventions: DRUG: corticosteroids|BEHAVIORAL: olfactory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Self-adhesive Silicone Gel Waterproof Dressings Versus Conventional Dressings in the Healing of Incisions After Total Joint Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Self-adhesive Silicone Gel Waterproof Dressing|Gauze Dressing|Total Joint Arthroplasty
Interventions: DEVICE: Self-adhesive silicone gel waterproof dressing|DEVICE: Sterile gauze dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Odor Management in Fungating Wounds Comparing Metronidazole and Polihexanide
Status: COMPLETED
Conditions: Neoplasm|Wounds and Injuries
Interventions: DRUG: Polihexanide 2%|DRUG: Metronidazole 0.8%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Papillomavirus Vaccine Safety & Immunogenicity Trial in Healthy Young Adult Women With HPV Vaccine (GSK1674330A)
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: GSK Biologicals' HPV vaccine (GSK1674330A)|BIOLOGICAL: Cervarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single Dose of Clonazepam Versus Intermiittent Diazepam for Febrile Seizures Prevention
Status: UNKNOWN
Conditions: Recurrent Febrile Convulsion
Interventions: DRUG: Clonazepam 0.5 MG|DRUG: Diazepam Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extension Study to Evaluate the Long-Term Safety and Tolerability of Ubrogepant in the Treatment of Migraine
Status: COMPLETED
Conditions: Migraine, With or Without Aura
Interventions: DRUG: Ubrogepant|DRUG: Placebo-matching Ubrogepant|DRUG: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proyecto BEBE: The Effect of Babywearing Education on Breastfeeding Exclusivity
Status: COMPLETED
Conditions: Breastfeeding, Exclusive|Mother-Infant Interaction|Postpartum Depression
Interventions: BEHAVIORAL: Babywearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMS Combined With EEG/EMG as a Biomarker Predicting Antiepileptic Drug Response
Status: RECRUITING
Conditions: Focal Epilepsy
Interventions: DEVICE: Software EstimLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cinnamon Trial-lIfestyle iNtervention Plus Water-soluble Cinnamon Extract On loweriNg Blood Glucose in Pre-diabetics
Status: COMPLETED
Conditions: Diabetes|Pre-Diabetes
Interventions: DRUG: water-soluble cinnamon extract (Cinnulin PF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Low Flow and Normal Flow Desflurane Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Liver Functions|Kidney Functions|Geriatric
Interventions: DRUG: Low flow desflurane anesthesia (Group D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influences of Phenylephrine, Dopamine and Ephedrine on Stroke Volume Variation and Pulse Pressure Variation
Status: COMPLETED
Conditions: Circulation|Drug Dose|Calculated SAP
Interventions: OTHER: Influences of phenylephrine, dopamine and ephedrine on stroke volume variation and pulse pressure variation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: