pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Invasive Breast Carcinoma|Locally Advanced HER2-Positive Breast Carcinoma|Metastatic HER2-Positive Breast Carcinoma|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Fulvestrant|BIOLOGICAL: Pertuzumab|OTHER: Quality-of-Life Assessment|DRUG: Ribociclib|BIOLOGICAL: Trastuzumab|DRUG: Tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Escalation Study to Evaluate Safety, Tolerability and Pharmacokinetics of Multiple Doses of Q203 in Normal Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Q203|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease
Status: UNKNOWN
Conditions: End Stage Liver DIsease
Interventions: DRUG: Mobilization with G-CSF and Mozobil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Pseudophakic Eyes
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: OMNI Surgical System|DRUG: Latanoprost plus adjunctive glaucoma medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot Study
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (Betaferon, BAY86-5046)|DEVICE: Betaconnect auto-injector|DEVICE: myBETAapp
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alveolar Bone Graft Cortical Nasal Floor
Status: COMPLETED
Conditions: Alveolar Cleft Operated on an Alveolar Bone Graft
Interventions: PROCEDURE: alveolar bone graft with cancellous bone and a cortical block|PROCEDURE: alveolar bone graft with cancellous bone only
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterization of Dynamic Stability in Normal Pressure Hydrocephalus and Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Hydrocephalus|Parkinson Disease|Walking, Difficulty|Movement Disorders|Gait Ataxia|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Dynamic stability measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Losartan potassium/Hydrochlorothiazide|DRUG: Losartan potassium/Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dopamine Treatment in Children With Cerebral Palsy With Dystonia- A Double Blind Controlled Study
Status: UNKNOWN
Conditions: Dystonic Cerebral Palsy
Interventions: DRUG: L- DOPA|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: PEG-asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Papillary Serous Carcinoma of the Endometrium
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: Paclitaxel|RADIATION: Pelvic Radiation|DRUG: Dexamethasone|DRUG: Cimetidine|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: AZD1775|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiotherapy Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of XP-004 Personalized mRNA Tumor Vaccine Combined With PD-1 Inhibitor for Postoperative Adjuvant Therapy for Pancreatic Cancer in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Pancreatic Cancer Recurrent
Interventions: BIOLOGICAL: Personalized tumor preventive vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.
Status: COMPLETED
Conditions: Nephrolithiasis
Interventions: DRUG: Ketorolac Oral Tablet [Toradol]|DRUG: Acetaminophen|DRUG: Oxycodone Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI
Status: WITHDRAWN
Conditions: Adverse Reaction to Diagnostic Agents and Kits Nos
Interventions: BIOLOGICAL: 19F Cell Sense-labeled PBMC|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Benefits While Reducing Risks of Iron in Malaria-endemic Areas
Status: ACTIVE_NOT_RECRUITING
Conditions: Iron Deficiency Anemia|Iron-deficiency|Anemia, Iron Deficiency|Anemia|Anemia in Children|Malaria
Interventions: DIETARY_SUPPLEMENT: Early Iron|DIETARY_SUPPLEMENT: Delayed Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Perfusion MRI to Measure the Dynamic Changes in Neural Activation Associated With Caloric Vestibular Stimulation
Status: COMPLETED
Conditions: Chronic Pain
Interventions: PROCEDURE: Caloric Vestibular Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Community-based Mental Health Care for People With Severe and Enduring Mental III Health ( RECOVER-E )
Status: UNKNOWN
Conditions: Severe Mental Disorder|Schizophrenia|Bipolar Disorder|Severe Depression
Interventions: OTHER: Community mental health teams (CMHT)|OTHER: Care as usual (CAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transcranial Direct Current Stimulation Influences on Cognitive Inhibition in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Individualized Exercise Program, Combined With a Balanced Diet on the Evolution of Body Fat
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: LIPOXmax|BEHAVIORAL: 60% VO2peak|BEHAVIORAL: Good Medical Practices|DIETARY_SUPPLEMENT: supplementation in fruits and vegetables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years
Status: COMPLETED
Conditions: Acellular Pertussis|Diphtheria|Tetanus
Interventions: BIOLOGICAL: Boostrix™|BIOLOGICAL: ADACEL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine
Status: COMPLETED
Conditions: Sleep
Interventions: DRUG: Naproxen Sodium 440 mg (BAYH6689) / DPH 50mg|DRUG: Naproxen Sodium 440 mg (BAYH6689)|DRUG: Naproxen Sodium 220 mg (BAYH6689) / DPH 50mg|DRUG: Naproxen Sodium 220 mg (BAYH6689)|DRUG: DPH 50mg|DRUG: Ibuprofen 400 mg / Diphenhydramine citrate 76 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I)
Status: UNKNOWN
Conditions: Recurrent Malignant Glioma
Interventions: DRUG: YYB-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comminuted Proximal Humeral Fractures. A Randomised Study of Surgical Versus Conservative Treatment
Status: COMPLETED
Conditions: Proximal Humeral Fracture|Osteosynthesis or Conservative Treatment
Interventions: PROCEDURE: Surgical treatment with LCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-osmolar Water Soluble Contrast Agent in Management of Adhesive Small Bowel Obstruction
Status: NOT_YET_RECRUITING
Conditions: Small Bowel Adhesion|Small Bowel Obstruction
Interventions: PROCEDURE: Low osmolar contrast|PROCEDURE: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal Endo Vascular Surgery for Central Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Central Retinal Vein Occlusion
Interventions: PROCEDURE: Retinal endo vascular surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Cylindrical Abdominoperineal Resection to Treat Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Treatment|Postoperative Complications|Neoplasm Recurrence, Local|Survival Rate
Interventions: PROCEDURE: cylindrical abdominoperineal resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised, Double-blind, Parallel Group, Placebo Controlled, 4-Week, Phase II Study to Evaluate the Effect of AZD4604 on Airway Inflammation and Biomarkers in Adults With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: AZD4604|DRUG: Placebo to AZD4604
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BMS-986165 on the Pharmacokinetics of Rosuvastatin
Status: COMPLETED
Conditions: Autoimmune Diseases|Inflammatory Diseases
Interventions: DRUG: BMS-986165|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Anthropometric Data, Shoulder Complex Muscle Strength, and Abdominal-lumbar Endurance in Closed Kinetic Chain Upper Extremity Stability Test
Status: RECRUITING
Conditions: Shoulder Pain
Interventions: DIAGNOSTIC_TEST: Closed Kinetic Chain Upper Extremity Stability Test|DIAGNOSTIC_TEST: Prone Bridge Test|DIAGNOSTIC_TEST: Measurement of the muscle strength of the shoulder complex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Anfibatide in Acquired Thrombotic Thrombocytopenic Purpura (TTP)
Status: UNKNOWN
Conditions: Acquired Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: Anfibatide|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment for Adenocarcinoma Patients With Epidermal Growth Factor Receptor (EGFR) Mutation
Status: COMPLETED
Conditions: Pulmonary Cancer
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Homeopathy in Patients With Resistant Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: OTHER: Homeopathy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Stimulation (VeNS): Assessment of AMPK & SIRT1 Following Repeated Usage
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: DEVICE: Electrical vestibular nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
Status: COMPLETED
Conditions: Alzheimer's Disease|Huntington's Disease
Interventions: DRUG: Dimebon alone|DRUG: Dimebon + Ketoconazole|DRUG: Dimebon + Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson's Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: SER-214
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Adverse Effect of Oral Contraceptives, Sequela
Interventions: DRUG: oc:E-E-desogestrel/vaginal ring:E-E -ethonogestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Prostate Cancer|Renal Cancer|Transitional Cell Carcinoma
Interventions: DRUG: GEM3PSCA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Nutraceutical Drinks For Cholesterol (Evaluating Effectiveness and Tolerability)
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Second Formulation|DIETARY_SUPPLEMENT: Third Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Topical Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Women With Twin Pregnancy
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: DRUG: Topical tranexamic acid|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Adult Soft Tissue Sarcoma|Bone Sarcoma|Retroperitoneal Sarcoma
Interventions: PROCEDURE: Real-Time CEUS|PROCEDURE: SWE|DRUG: Definity Suspension for Injection|DEVICE: Philips Shear Wave Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of LC51-0255 in Subjects With Ulcerative Colitis
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: LC51-0255|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Training Program for Developing Social- and Personal Resources
Status: SUSPENDED
Conditions: Stress, Psychological|Stress, Emotional|Health Behavior|Satisfaction, Personal|Somatic Symptom|Psychophysiology|Family Relations|Program Evaluation
Interventions: BEHAVIORAL: Training Program for Developing Social- and Personal Resources
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Mechanical Methods of Outpatient Ripening of the Cervix
Status: TERMINATED
Conditions: Induction of Labor
Interventions: DEVICE: Trans-cervical cervical balloon|DEVICE: Hygroscopic cervical dilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 and Dentoalveolar Cyst
Status: NOT_YET_RECRUITING
Conditions: Cyst, Jaw
Interventions: DRUG: Coenzyme Q10|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases
Status: RECRUITING
Conditions: Glioma, Malignant|Metastases to Brain
Interventions: DEVICE: Combined ultrasound and fluorescence-guided brain tumor resection|DEVICE: Fluorescence-guided brain tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Electrophysiological Data During Colon Resection
Status: COMPLETED
Conditions: Open/ Laparoscopic/ Robotic Resection of the Colon
Interventions: DEVICE: Exero Medical Leak Detection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
Status: COMPLETED
Conditions: Lentigines|Post Inflammatory Hyperpigmentation
Interventions: DRUG: topical 0.05% Clobetasol propionate ointment|DEVICE: Q switched Nd:YAG laser 532 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Comparing 0.9 g and 1.25 g Estrogel With Placebo for Vasomotor Symptoms and Vulvar and Vaginal Atrophy
Status: COMPLETED
Conditions: Postmenopausal Symptoms
Interventions: DRUG: Estrogel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reiki on the Stress Level of Caregivers of Cancer Patients
Status: COMPLETED
Conditions: Caregiver Stress Syndrome|Reiki|Caregiver Burnout
Interventions: OTHER: Reiki|OTHER: Sham Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Hydrolyzed Casein on Energy Expenditure and Subjective Appetite
Status: COMPLETED
Conditions: Increased Energy Expenditure|Increased Satiety
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed casein|DIETARY_SUPPLEMENT: Intact casein|DIETARY_SUPPLEMENT: Intact whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: This Study Tests Whether BI 425809 Together With Brain Training Using a Computer Improves Mental Functioning in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: BI 425809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients
Status: RECRUITING
Conditions: Cancer
Interventions: OTHER: Pre-Test Intervention|OTHER: Standard of Care|OTHER: Post-Test Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
Status: NOT_YET_RECRUITING
Conditions: Estrogen Receptor-Positive Breast Carcinoma|HER2-Negative Breast Carcinoma
Interventions: DRUG: Coriolus Versicolor Extract|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Immunogenicity of a Vaccine Designed to Protect Against Infection With Shigella Sonnei in Healthy Adults
Status: COMPLETED
Conditions: Dysentery, Bacillary
Interventions: BIOLOGICAL: S.sonnei vaccine|DRUG: Placebo|BIOLOGICAL: S. sonnei 53G challenge strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers
Status: UNKNOWN
Conditions: Frontotemporal Lobar Degeneration
Interventions: BEHAVIORAL: Behavioral : Characterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: MGA031, Sirolimus and Tacrolimus in Islet Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia
Interventions: BIOLOGICAL: Allogeneic Islets of Langerhans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online CBT, Mindfulness Meditation & Yoga (CBT-MY) Intervention for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders|PTSD
Interventions: BEHAVIORAL: Online Mindfulness-Based CBT & Trauma-Informed Yoga Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-EUS for Gastrointestinal Disorders: A Multicenter Registry
Status: UNKNOWN
Conditions: Cholangiocarcinoma|Pancreatic Cancer|Bile Duct Cancer|Biliary Stricture|Biliary Obstruction|Stent Obstruction|Proximal Duct Stricture|Distal Duct Stricture|Ampullary Cancer|Biliary Sphincter Stenosis|Impacted Stones|Chronic Pancreatitis|Peri-ampullary Diverticula|Altered Anatomy
Interventions: PROCEDURE: EUS guided ERCP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GOELAMS SA4 Study: the Role of Fludarabine in the Treatment of Acute Myeloid Leukemia in the Elderly
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Active comparator (no fludarabine)|DRUG: Experimental (fludarabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CLPG Topical Gel 1%|DRUG: Clindamycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders
Status: WITHDRAWN
Conditions: Osteoporosis|Juvenile Rheumatoid Arthritis|Dermatomyositis|Polyarthritis|Systemic Lupus Erythematosis|Vasculitis|Glucocorticoid-induced Osteoporosis
Interventions: DRUG: denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triggering of Follicular Maturation
Status: COMPLETED
Conditions: Increase Pregnancy Rate
Interventions: DRUG: Recombinant Human Chorionic Gonadotrophin|DRUG: human chorionic gonadotrophin + gonadotrophin releasing hormone agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effcet of Temporomandibular Joint Disorder Relaxation and Myofacial Relaxation Techniques on Tension Headache
Status: UNKNOWN
Conditions: Tension-Type Headache
Interventions: OTHER: Control group (n=22)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Healthy Aging Through Functional Food
Status: COMPLETED
Conditions: Glucose Intolerance|Aortic Stiffness|Vasodilation
Interventions: DIETARY_SUPPLEMENT: Glyoxalase 1 (Glo1) inducer|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Cabozantinib in Japanese Participants With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-IgE in Non-Allergic Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: omalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine (HOE901)|DRUG: Neutral Protamine Hagedorn (NPH) insulin|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-680 After Multiple Oral Doses"
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PBF-680|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Hepaticojejunostomy Versus Duct-to-duct Anastomosis in Right Lobe Living Donor Liver Transplantation
Status: UNKNOWN
Conditions: Liver Failure
Interventions: PROCEDURE: Hepaticojejunostomy / Duct-to-duct anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DNA Exome Sequencing TCM for Sjögren's Syndrome
Status: UNKNOWN
Conditions: Sjögren's Syndrome
Interventions: DIAGNOSTIC_TEST: DNA Exome sequencing|DIAGNOSTIC_TEST: Oral microbiome|DIAGNOSTIC_TEST: Proteomics|DIAGNOSTIC_TEST: RNA sequencing|DIAGNOSTIC_TEST: Cytokine|DIAGNOSTIC_TEST: Traditional Chinese Medicine pattern|DIAGNOSTIC_TEST: Traditional Chinese Medicine tongue diagnosis|DIAGNOSTIC_TEST: Traditional Chinese Medicine pulse diagnosis|DIAGNOSTIC_TEST: Heart rate variability|DIAGNOSTIC_TEST: Schirmer's test|DIAGNOSTIC_TEST: Blood function test, liver function test, kidney function test, and immune function test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study Class II on Ceram.x Universal and Prime&Bond
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Prime & Bond Universal|DEVICE: Ceram X|DEVICE: Prime & Bond XP|PROCEDURE: technique 1|PROCEDURE: technique 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Addition of Platelet Rich Plasma (PRP) in Microfat Lipofilling (MG) in the Treatment of Cranial Flap Scars: A Randomized, Double-blind, Superiority Study
Status: RECRUITING
Conditions: Facial Lipofilling
Interventions: OTHER: intra-articular injection|RADIATION: RMI SCANS|OTHER: RMI SCANS|OTHER: RMI SCAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testogel® (Testosterone Gel 50mg/5g) in the Treatment of Male Hypogonadism
Status: UNKNOWN
Conditions: Hypogonadism
Interventions: DRUG: Testogel 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Methadone Maintenance Therapy on Food Reward Processing in Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence|Obesity
Interventions: BEHAVIORAL: Sniffin' Sticks Odor Identification and Hedonic Scale|BEHAVIORAL: Sucrose Taste Preference Assessment|BEHAVIORAL: Food Preferences Task|BEHAVIORAL: Progressive Ratio (PR) Task|PROCEDURE: Clinical Electrophysiology|DIETARY_SUPPLEMENT: Standardized Meal and Hunger and Satiety Ratings
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study To Assess Efficacy and Safety of Oglemilast in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Oglemilast|DRUG: Placebo|DRUG: Oglemilast|DRUG: Oglemilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Serum Free Thyroxine (FT4) and Free Triiodothyronine (FT3) Measurements for Subjects Treated With Eslicarbazeine Acetate (ESL)
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors
Status: RECRUITING
Conditions: Refractory Solid Tumors
Interventions: DRUG: Eribulin|DRUG: Irinotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine (CAM2038) in Subjects With a Recent History of Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Lower Back Pain|Chronic Pain
Interventions: DRUG: buprenorphine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing Cancers
Status: COMPLETED
Conditions: Esophageal Cancer|Lung Cancer|Stomach Cancer|Breast Cancer|Ovarian Cancer
Interventions: DRUG: CHP-HER2, CHP-NY-ESO-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-Based Versus Partner-Friendly Clinic Testing to Enhance Male Partner HIV-1 Testing During Pregnancy
Status: COMPLETED
Conditions: Male Partner|HIV Counseling and Testing|Home Based|Pregnancy
Interventions: OTHER: HIV counseling and testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Status: COMPLETED
Conditions: Fibromyalgia|Irritable Bowel Syndrome|Burning Mouth Syndrome
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project Health Link: Connecting Patients With Services
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: Strengths Based Case Management (SBCM)|BEHAVIORAL: Motivational Enhancement Therapy (MET)|BEHAVIORAL: Brief Informational Feedback (BIF) session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Functional Massage of Teres Major Muscle
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome|Trigger Points
Interventions: OTHER: Functional Massage|OTHER: Protocolized physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRevention of End Stage Kidney Disease by Darbepoetin Alfa In Chronic Kidney Disease Patients With nondiabeTic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetes
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Metastases In ErbB2-Positive Breast Cancer
Status: TERMINATED
Conditions: Neoplasms, Breast
Interventions: DRUG: capecitabine|DRUG: topotecan|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: DSTP3086S|DRUG: DSTP3086S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Natural and Interesterified Fats-margarine on Lipemic and Insulinemic Response
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Trans free palm margarine|OTHER: Interesterified Palm based margarine|OTHER: IE Soybean oil-based margarine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Desoximetasone (DSXS) With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: DSXS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas
Status: RECRUITING
Conditions: Advanced Solid Tumors|B-cell Non-Hodgkin Lymphomas
Interventions: DRUG: ATG-031
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutein, Zeaxathin, and Fish Oil Supplementation
Status: RECRUITING
Conditions: Cognitive Performance|Age-Related Macular Degeneration|Bone Loss
Interventions: DIETARY_SUPPLEMENT: Active Comparator (Lutein, zeaxanthin, and fish oil supplement (LZF)|DIETARY_SUPPLEMENT: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.
Status: COMPLETED
Conditions: T2DM
Interventions: DRUG: Chiglitazar|DRUG: Empagliflozin|DRUG: Atorvastatin|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iso-Osmolar vs. Low-Osmolar Contrast Agents for Optical Coherence Tomography
Status: UNKNOWN
Conditions: Coronary Artery Disease|Contrast Media Reaction
Interventions: DRUG: Iodixanol|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurocognitive Outcome of Conformal WBRT w/wo Hippocampal Avoidance for Brain Metastases
Status: UNKNOWN
Conditions: Metastatic Malignant Neoplasm to Brain
Interventions: RADIATION: Hippocampal avoidance WBRT|RADIATION: Conformal WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D, SSRIs and the Musculoskeletal System
Status: COMPLETED
Conditions: Major Depression|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: cholecalciferol (50ug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.
Status: COMPLETED
Conditions: Biliary Tract Cancer|Anti-PD-1 Therapy|Targeted Molecular Therapy|Capecitabine
Interventions: DRUG: Camrelizumab|DRUG: apatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Handling Oxygenation Targets in COVID-19
Status: COMPLETED
Conditions: Hypoxemic Respiratory Failure|Oxygen Toxicity
Interventions: DRUG: Low oxygenation target|DRUG: High oxygenation target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Low-dose vs. High-dose Pitavastatin on In-stent Restenosis
Status: COMPLETED
Conditions: Atherosclerosis|Neointima|Angina
Interventions: DRUG: Pitavastatin 1mg|DRUG: Pitavastatin 4mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation of Post-stroke Aphasia by Targeting Phonological, and Lexico-semantic Deficits With Speech Output Tasks
Status: COMPLETED
Conditions: Aphasia, Acquired|Stroke|Anomia
Interventions: BEHAVIORAL: PHOLEXSEM|BEHAVIORAL: PACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers
Status: RECRUITING
Conditions: Hepatobiliary Cancer|Pancreatic Cancer|Hepatocellular Carcinoma|Cholangiocarcinoma|Ampullary Cancer|Pancreatic Carcinoma
Interventions: DIAGNOSTIC_TEST: ctDNA Blood Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2
Status: RECRUITING
Conditions: Mitral Valve Prolapse
Interventions: PROCEDURE: Cardiac MRI|OTHER: Blood collection|PROCEDURE: Prolongation of the MRI examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Telemonitoring and Connected Care Applied to Multiple Sclerose
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: MSmonitor, a self-management/education program with e-health interventions|DEVICE: Video calling program "Better-close"|DEVICE: Researchmanager program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Drug-Drug Interaction Study to Assess the Effects of Multiple-Dose Administration of K-877 on the Pharmacodynamics and the Pharmacokinetics of Multiple-Dose Administration of Warfarin in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Warfarin|DRUG: K-877
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumour DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II Evaluation
Status: RECRUITING
Conditions: Colon Cancer Stage II
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Perioperative Related Factors and Inflammatory Markers and Postoperative Delirium in Elderly Patients With Non-cardiac Major Surgery
Status: NOT_YET_RECRUITING
Conditions: Preoperative Sleep Disorder|Preoperative Anxiety|Inflammatory Reaction|Postoperative Delirium
Interventions: OTHER: elderly patients undergoing non-cardiac surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Fragmin/ Dalteparin Sodium|DRUG: Placebo for Fragmin/ Dalteparin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Milled Seed Mix in Patients With Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Non-hodgkin Lymphoma
Interventions: DIETARY_SUPPLEMENT: Milled seed mix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PillCam™ Colon 2 in Visualization of the Colon
Status: COMPLETED
Conditions: Colonic Diseases|and Large Bowel Diseases
Interventions: DEVICE: PillCam™ (Capsule Endoscopy) Colon 2 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Dapagliflozin, Added to Therapy of Patients With Type 2 Diabetes With Inadequate Glycemic Control on Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin|DRUG: Dapagliflozin|DRUG: Placebo|DRUG: Dapagliflozin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD2373 subcutaneous injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)
Status: TERMINATED
Conditions: Tumor, Solid
Interventions: DRUG: MK-8353
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach to Methicillin-resistant Staphylococcus Aureus (MRSA) Screening of Colonized Patients
Status: COMPLETED
Conditions: MRSA Colonization
Interventions: DEVICE: nucleic acid amplification of nasal swab; nasal swab culture|OTHER: Nasal swab culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I Study of LFA102 in Patients With Prolactin Receptor-positive Castration-resistant Prostate Cancer or Prolactin Receptor-positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Castration-resistant Prostate Cancer|Metastatic Breast Cancer|Uterine Leiomyoma
Interventions: DRUG: LFA102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT