pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: Chlorhexidine gel|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of How Long it Takes a Patient to Relapse After Switching From an Oral Antipsychotic to One of Two Doses of Long-acting Risperidone Injections in Patients With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Risperidone, long-acting injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of Dynamic Arm Supports to Promote Activities of Daily Living in Individuals With DMD
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DEVICE: Armon Ayura (Kinova)|DEVICE: JAECO Wrex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone
Status: COMPLETED
Conditions: Candidiasis|HIV Infections
Interventions: DRUG: Methadone hydrochloride|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Foot Core Exercise Program on Balance Control and Walking in Aged Sarcopenia
Status: RECRUITING
Conditions: Sarcopenia|Muscle Weakness|Walking, Difficulty|Balance Control
Interventions: BEHAVIORAL: integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles|BEHAVIORAL: regular exercises for the elderly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of Folic Acid Fortified Bread
Status: COMPLETED
Conditions: Red Blood Cell Folate
Interventions: DIETARY_SUPPLEMENT: Folic acid|DIETARY_SUPPLEMENT: L-5-MTHF|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: VENEK: Healing in Different Vein Harvesting Methods During Aortocoronary Coronary Artery Bypass Graft Surgery (CABG)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: endoscopic vein harvesting|PROCEDURE: open vein harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypnotherapeutic Sound-files on the Sleep of Parents in the Neonatal Unit.
Status: RECRUITING
Conditions: Parents|Sleep|Infant, Premature|Hypnosis
Interventions: OTHER: Hypnotherapeutic sound-files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: DRUG: Odronextamab|DRUG: Loncastuximab tesirine|DRUG: Rituximab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Etoposide Phosphate|DRUG: Dexamethasone|BIOLOGICAL: CAR T-cells (TBC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Mobile Health Breastfeeding Counseling Intervention for Employed Mothers in Kenya
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding, Exclusive
Interventions: BEHAVIORAL: mobile Health Breastfeeding Counseling|BEHAVIORAL: Standard of care breastfeeding counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Netarsudil Ophthalmic Solution 0.02%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy Safety and Tolerability of Nitric Oxide Given Intermittently Via Inhalation to Subjects With Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Nitric Oxide|OTHER: Supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Handgrip Strengthening Exercise in Treatment of the Patients With Primary Sub-Acromial Impingement Syndrome
Status: UNKNOWN
Conditions: Impingement Syndrome, Shoulder
Interventions: BEHAVIORAL: Hand grip strengthening|BEHAVIORAL: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Study of Del-desiran for the Treatment of DM1
Status: RECRUITING
Conditions: DM1|Myotonic Dystrophy|Myotonic Dystrophy 1|Myotonia|Myotonic Dystrophy Type 1 (DM1)|Dystrophy Myotonic|Myotonic Disorders|Steinert Disease|Steinert|Myotonic Muscular Dystrophy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Melatonin on IVF/ICSI Outcomes in Prospective Poor Responders
Status: UNKNOWN
Conditions: In Vitro Fertilization|Poor Ovarian Response
Interventions: DRUG: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Coping and Resilience Intervention in Adolescents
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: BEHAVIORAL: Coping and Resilience Intervention for Adolescents|OTHER: Printing materials of Coping and Resilience Intervention for Adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Cholangiocarcinoma|Metastatic Cholangiocarcinoma|Recurrent Cholangiocarcinoma|Stage III Hilar Cholangiocarcinoma AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Hilar Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic Transplantation
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Leukapheresis|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: CAR19 T-Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Continuous Noninvasive Haemoglobin Monitoring by the Radical 7 Pulse CO-Oximetry Monitor After in Vivo Adjustment.
Status: UNKNOWN
Conditions: Sphb Haemoglobin in Vivo Validation
Interventions: DEVICE: Masimo Radical 7
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Nexpowder™ for Non-variceal, Upper Gastrointestinal Bleeding
Status: RECRUITING
Conditions: Gastrointestinal Hemorrhage|Hematemesis; With Ulcer|Endoscopy
Interventions: DEVICE: Nexpowder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome
Status: COMPLETED
Conditions: Pregnancy|Birth Weight
Interventions: DIETARY_SUPPLEMENT: multi micronutrient supplement|DIETARY_SUPPLEMENT: MN1|DIETARY_SUPPLEMENT: MN2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The NIH UNI Study: Urea Cycle Disorders, Nutrition and Immunity
Status: TERMINATED
Conditions: Argininosuccinic Aciduria|Carbamoyl-Phosphate Synthase I Deficiency|Citrullinemia|Ornithine Carbamoyltransferase Deficiency|Hyperargininemia|N-Acetylglutamate Synthase Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapy Study of Automated Protocolized vs. Physician-Directed Non-Protocolized Weaning
Status: SUSPENDED
Conditions: Neoplasms|Musculoskeletal Diseases|Digestive System Diseases|Respiratory Tract Diseases|Cardiovascular Diseases
Interventions: DEVICE: SmartCare/PS (Automated Weaning)|PROCEDURE: Conventional weaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Rising Oral Dose Study of PG 760564 Administered Twice Daily to Healthy Male/Female Volunteers for 14 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: PG-760564|DRUG: PG-760564|DRUG: PG-760564|DRUG: PG-760564
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Trial to Evaluate the Safety and Efficacy of DBI-001 Gel, DBI-002 Gel, and Aqueous Gel in Subjects With Tinea Pedis
Status: UNKNOWN
Conditions: Tinea Pedis
Interventions: BIOLOGICAL: DBI-001 Gel|BIOLOGICAL: DBI-002 Gel|BIOLOGICAL: Aqueous Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of Two Animal-derived ADMs in Irradiated Implant-based Reconstruction
Status: COMPLETED
Conditions: Breast Implant; Complications|Breast Implant Infection|Implant Capsular Contracture|Breast Seroma|Breast Implant Protrusion|Breast Cancer
Interventions: DEVICE: acellular dermal matrix implant for breast reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride (HCL) 1% Cream for Erythematotelangiectatic Rosacea
Status: COMPLETED
Conditions: Erythematotelangiectatic Rosacea
Interventions: DEVICE: The Vbeam® Prima System|DRUG: Oxymetazoline HCL 1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talquetamab & Lenalidomide as Post Stem Cell Transplant Maintenance in Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma|Post Stem Cell Transplant
Interventions: DRUG: Talquetamab|DRUG: Talquetamab and Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Clinical Observation of an Inactivated Influenza Split Vaccine
Status: COMPLETED
Conditions: Human Influenza
Interventions: BIOLOGICAL: Inactivated Influenza Vaccine|BIOLOGICAL: Inactivated Influenza Vaccine of Pasteur|BIOLOGICAL: Inactivated Influenza Vaccine of GSK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation Acute Stroke Walking
Status: UNKNOWN
Conditions: Acute Stroke
Interventions: DEVICE: Anodal Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine (NAC) for Children With Tourette Syndrome
Status: COMPLETED
Conditions: Tourettes Syndrome|Tic
Interventions: DRUG: N-Acetylcysteine (NAC)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kangaroo Position on Electromyographic Activity, Macrocirculation and Microcirculation of Preterm Newborns
Status: UNKNOWN
Conditions: Kangaroo Mother Care Method
Interventions: OTHER: Kangaroo Position.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Value of Penile Elastography in Diagnosis of Patients With Erectile Dysfunction and Non-responders to Intra-corporal Injection
Status: COMPLETED
Conditions: To Investigate the Value of Penile Elastography in the Diagnosis of Fibrosis of CC
Interventions: DEVICE: Shear Wave Elastography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo
Status: COMPLETED
Conditions: Bloodstream Infection|Health Care Utilization|Malaria,Falciparum|Salmonella Infection Non-Typhoid|Febrile Illness
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omicron BA.4/5-Delta COVID-19 Vaccine Phase I Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Systemic Lidocaine for Enhanced Bowel Recovery After Bariatric Surgery
Status: SUSPENDED
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: DRUG: Placebo|DRUG: Lidocaine 1%|DRUG: Lidocaine 1.5%|DRUG: Lidocaine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: DRUG: Atezolizumab 1200 MG in 20 ML Injection|RADIATION: Stereotactic Body Radiation Therapy|DRUG: Varlilumab 3 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis
Status: COMPLETED
Conditions: Strongyloides Stercoralis Infection
Interventions: DRUG: Moxidectin 2 mg|DRUG: Ivermectin 3 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycyphagus Domesticus Allergen Extract. Determination of the in Vivo Biological Activity in Histamine Equivalent Units (HEP).
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Conjunctivitis, Allergic
Interventions: OTHER: Standardization of allergenic extract (Gly. domesticus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chinese Acupuncture for Chemobrain in Elderly Cancer Patients
Status: RECRUITING
Conditions: Chinese Acupuncture
Interventions: DEVICE: Chinese acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Weekly Carboplatin and Taxotere in Platinum Sensitive Relapsed Ovarian or Tubal or Primary Peritoneal Cancers
Status: TERMINATED
Conditions: Platinum Sensitive Relapsed Ovarian Cancer
Interventions: DRUG: Weekly Taxotere with weekly carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-90011 and Comparators in Participants With Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: CC-90011|DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Immunosuppression in Myocarditis or Inflammatory Cardiomyopathy.
Status: RECRUITING
Conditions: Myocarditis|Heart Failure|Endomyocardial Biopsy|Cardiomyopathies, Secondary|Immunosuppression
Interventions: DRUG: Prednisone|DRUG: Azathioprine|DRUG: Placebo Prednisone|DRUG: Placebo Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Kinesiotape on Treatment of Nonspecific Cardiac Chest Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonspecific Cardiac Chest Pain
Interventions: OTHER: experimental|OTHER: traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of V0018 2.5 mg Effect on Craving
Status: COMPLETED
Conditions: Healthy Highly Dependant Smokers
Interventions: DRUG: V0018|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trail of Polyethylene Glycol vs Sodium Phosphate for Colonic Cleansing of Colonoscopy
Status: COMPLETED
Conditions: Polyethylene Glycol|Sodium Phosphate
Interventions: DRUG: polyethylene glycol|DRUG: sodium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Trial of Letters From Family Physicians to Encourage Screening Mammography in Overdue Women
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Standard Reminder Postcard|OTHER: Family Physician Reminder Letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation Study on Corneal Lens for Vision Correction
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: Astigmatic Correction Lens (Nexis ACCL lenses)|DEVICE: Toric Soft Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Glucose Dependent Insulinotropic Polypeptide (GIP) on Subcutaneous Adipose Tissue
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Insulin Sensitivity
Interventions: OTHER: Glucose dependent insulinotropic polypeptide (GIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surface EMG Biofeedback for Children With Cerebral Palsy
Status: WITHDRAWN
Conditions: Cerebral Palsy|Dystonia|Hypertonia|Spasticity|Movement Disorders
Interventions: DEVICE: Sanger EMG Biofeedback Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs
Status: COMPLETED
Conditions: Healthy Subjects|Infection, Human Immunodeficiency Virus
Interventions: DRUG: darunavir/ritonavir|DRUG: lopinavir/ritonavir|DRUG: Midazolam|DRUG: Dextromethorphan|DRUG: Flurbiprofen|DRUG: GSK2248761
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of Bronchial Thermoplasty Performed With the Alair® System During Two Treatment Sessions to Treat Severe Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DEVICE: The Alair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Strategies to Prevent Intradialytic Hypotension (The DialHypot Study)
Status: UNKNOWN
Conditions: Hypotension During Dialysis|Dialysis Hypotension
Interventions: OTHER: UF and Na profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of alloCART-19 Cell Therapy in Pediatric Patients With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: ALL, Childhood B-Cell
Interventions: GENETIC: alloCART-19|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity|Obesity, Abdominal|Liver Fat|Fatty Liver
Interventions: DRUG: Tesamorelin|DRUG: Identical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lurbinectedin in Patients With Advanced Gastrointestinal Malignancies With DNA Repair Mutations
Status: RECRUITING
Conditions: Gastrointestinal Malignancies
Interventions: DRUG: Lurbinectedin 4 MG Injection [Zepzelca]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil in the Treatment of PTSD (Posttraumatic Stress Disorder)
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Analgesics in Orthodontic Treatment
Status: COMPLETED
Conditions: NSAID|Pain Management
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: MK-0893|DRUG: Sitagliptin|DRUG: Metformin|DRUG: Placebo for MK-0893|DRUG: Placebo for Sitagliptin|DRUG: Placebo for Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Ammoxetine Hydrochloride Enteric-coated Tablets|DRUG: placebo enteric-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMPIRE CF: A Phase 2 Study to Evaluate the Efficacy, Safety, and Tolerability of CTX-4430 in Adult Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: CTX-4430|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of ACBT and Diaphragmatic Breathing on Pulmonary Function and Sputum Diary After CABG
Status: COMPLETED
Conditions: Breathing Exercises
Interventions: OTHER: Active cycle of breathing technique|OTHER: diaphragmatic breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Itraconazole on Pharmacokinetics (PK) of SHR8554 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SHR8554；Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Prolonged Exposure Therapy|DRUG: Paroxetine-CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact Lenses
Status: COMPLETED
Conditions: Contact Lens Wearer
Interventions: DEVICE: All participants received Biotrue ONEday lenses with and without an alternate packaging solution (EPG03)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Changes in TMJ by Twin Block Therapy in Skeletal Class II Div 2 Malocclusion in Adolescent Females : MRI Study"
Status: COMPLETED
Conditions: Class II Division 2 Malocclusion
Interventions: PROCEDURE: Functional appliance therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate Intensity Soleus Push-ups vs Sustained Soleus Push-ups on Lipid Profile Among Young Population
Status: RECRUITING
Conditions: Health Behavior
Interventions: BEHAVIORAL: Short Duration Moderate Intensity Soleus Push-ups|BEHAVIORAL: SUSTAINED SOLEUS PUSH-UPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Systemic Isotretinoin on Serum Irisin Level in Acne Vulgaris Patients
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Passive Lower-limb Exoskeleton-assisted Training on Motor and Daily Function Improvements in Older Adults
Status: RECRUITING
Conditions: Multidomain Intervention
Interventions: BEHAVIORAL: passive exoskeleton- assisted gait training programs|BEHAVIORAL: Conventional gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Regional or General Anesthesia for Distal Radius Fracture Surgery in a Day Surgery Setting
Status: COMPLETED
Conditions: Distal Radius Fracture|Postoperative Pain
Interventions: PROCEDURE: Regional anesthesia|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Portico Valve-in-Valve Retrospective Registry
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Aortic Valve Failure|Aortic Insufficiency|Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Nursing Care on Maternal Role Performance and Parental Self-Efficacy of Primiparous Women
Status: COMPLETED
Conditions: Primiparous Women
Interventions: BEHAVIORAL: Physical, psychological and spiritual nursing care (Nursing Therapeutics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic Ultrasound (EUS)-Guided Fine Needle Aspiration (FNA) With Rapid On-site Evaluation (ROSE) of Cytopathology vs. EUS-guided Fine Needle Biopsy (FNB) Alone in the Diagnosis of Pancreatic Solid Lesions
Status: COMPLETED
Conditions: Solid Pancreatic Tumor
Interventions: PROCEDURE: EUS|PROCEDURE: FNA with ROSE|PROCEDURE: FNB alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluating Lymphatic and Venous Disorders (VOLGA)
Status: RECRUITING
Conditions: Lymphedema|Chronic Venous Insufficiency|Edema|Venous Insufficiency of Leg
Interventions: DIAGNOSTIC_TEST: Insight Pro Device for Diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stool Biobanking and Impact of Antimicrobials on the Gut Microbiota in Patients With Bone and Joint Infection
Status: TERMINATED
Conditions: Infection, Bacterial
Interventions: BIOLOGICAL: Patients treated by antibiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Minimally Invasive Image Guided Endoscopic Evacuation of Intracerebral Haemorrhage (EMINENT-ICH)
Status: RECRUITING
Conditions: Intracerebral Haemorrhage
Interventions: PROCEDURE: Early minimally invasive image guided endoscopic hematoma evacuation|PROCEDURE: Best medical treatment (BMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Health Record-leveraged, Patient-centered, Intensification of Chronic Care for HF
Status: COMPLETED
Conditions: Patient Engagement|Medication Optimization|Heart Failure With Reduced Ejection Fraction|Patient Activation
Interventions: BEHAVIORAL: Patient engagement materials|BEHAVIORAL: No Intervention--Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Pharmacokinetics (PK) and Relative Bioavailability of NTP42:KVA4 as a Solid Oral Dose
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: NTP42:KVA4 Capsule|DRUG: NTP42:KVA4 Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Patient Acceptance of Sound Amplifier Téo First, in Mild and Moderate Presbycusis Patient 60 Years of Age and Older, With no Previous Hearing Aid
Status: COMPLETED
Conditions: Mild and Moderate Presbycusis
Interventions: DEVICE: Use of a personal sound amplifying device = TeoFirst
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Atezolizumab|DRUG: 5-Fluorouracil|DRUG: Calciumfolinat|DRUG: Oxaliplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Several Contact Lenses in Extended Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: senofilcon A|DEVICE: lotrafilcon A|DEVICE: lotrafilcon B|DEVICE: balafilcon A|DEVICE: comfilcon A|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Allogeneic Gammadelta T Cells Combined With Interferon-α1b or PD-1 Monoclonal Antibody in Stage III-IV Amenable to Surgical Resection Melanoma
Status: NOT_YET_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Ex-vivo expanded allogeneic γδ T cells|DRUG: Recombinant human interferon α1b|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Calcium and Sodium Phosphosilicate (Novamin) in the Treatment of MIH (Molar Incisor Hypolimineralization) in Pediatric Patients
Status: ENROLLING_BY_INVITATION
Conditions: Molar Incisor Hypomineralization
Interventions: OTHER: Novamin application|OTHER: Parodontax application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy to Treat Actinic Damage in Patients With Squamous Cell Carcinoma (SCC) of the Lip
Status: COMPLETED
Conditions: Actinic Cheilitis|Squamous Cell Carcinoma In-situ (SCC-is)|Squamous Cell Carcinoma (SCC)|Photodynamic Therapy (PDT)|Mohs Surgery
Interventions: PROCEDURE: PDT prior to Mohs surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of an Interactive Web-based Teaching Tool for in Vitro Fertilization (IVF) Patients
Status: UNKNOWN
Conditions: Education
Interventions: OTHER: Knowledge Questionnaire|OTHER: Perceived Stress Scale|OTHER: Satisfaction questionnaire|OTHER: Web-based IVF teaching|OTHER: Didactic lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Prophylactic White Cell Transfusions Versus Therapeutic White Cell Transfusions in Patients With Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: PROCEDURE: Prophylactic White Cell Transfusion|PROCEDURE: Therapeutic White Cell Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
Status: UNKNOWN
Conditions: Prostatic Neoplasms, Prostatectomy
Interventions: DRUG: tamsulosin 0.4mg|OTHER: No medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Eluxadoline for Diabetic Diarrhea
Status: WITHDRAWN
Conditions: Diabetic Diarrhea|Diabetes|Diarrhea
Interventions: DRUG: Eluxadoline 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co Enzyme Q10 Improves IVF Outcome in With Advanced Reproductive Age
Status: UNKNOWN
Conditions: Ovarian Function at Advanced Reproductive Age
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10 concomitant treatment|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphatic System Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Echocardiography|PROCEDURE: Radionuclide Imaging|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Therapeutic Options for Subjects Discontinuing Efalizumab and Experiencing Disease Recurrence
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Cyclosporins|DRUG: Retinoids|DRUG: Systemic corticosteroids|DRUG: Methotrexate|DRUG: Systemic corticosteroids/methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost Study Comparing Two Ways to Deliver Albuterol for the Treatment of Asthma in the Hospital
Status: COMPLETED
Conditions: Status Asthmaticus
Interventions: DEVICE: Metered Dose Inhaler & Optichamber Advantage Valve Holding Chamber (VHC)|DEVICE: Airlife Sidestream High Efficiency Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Centralized Virtual SBIRT for Pediatric Primary Care
Status: RECRUITING
Conditions: Adolescent Alcohol Use|Mental Health Issue|Alcohol Related Disorders|Adolescents
Interventions: BEHAVIORAL: Centralized Virtual SBIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intervention for Adolescent Tobacco Initiation Prevention
Status: NOT_YET_RECRUITING
Conditions: Health Behaviour|Tobacco Prevention|Well-being
Interventions: BEHAVIORAL: Intervention for Adolescent Tobacco Initiation Prevention (IATIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Use of Continuous Glucose Monitors in a Short-term 2x2-Crossover Study
Status: COMPLETED
Conditions: Diabetes Type 2|Diabetes Mellitus
Interventions: OTHER: WB-011|OTHER: Placebo|DEVICE: Continuous Glucose Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effect of Nutritional Supplementation on Skeletal Muscle Mass in Patients Awaiting Lung Transplant
Status: ENROLLING_BY_INVITATION
Conditions: Lung Transplant; Complications
Interventions: DIETARY_SUPPLEMENT: Ensure Enlive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Lurbinectedin (PM01183) in Platinum Resistant Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Lurbinectedin (PM01183)|DRUG: Pegylated liposomal doxorubicin (PLD)|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation"
Status: COMPLETED
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: Kamada-AAT for Inhalation, 80mg|DRUG: Placebo|DRUG: Kamada-AAT for Inhalation, 160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ZK219477 in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Sagopilone (BAY86-5302 , ZK219477)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resin Infiltration and Resin Infiltration With Bleaching in Improving the Esthetics for Fluorosis Stains
Status: COMPLETED
Conditions: Caries Infiltration|Fluorosis|Dental Care
Interventions: DEVICE: Office Bleaching|DEVICE: Resin Infiltration|DEVICE: Resin Infiltration twice|DEVICE: Bleaching + Resin Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of BC-819/PEI and BCG in Patients With Superficial Transitional Cell Bladder Carcinoma
Status: COMPLETED
Conditions: Transitional Cell Carcinoma of Bladder
Interventions: DRUG: BC-819/PEI|DRUG: BCG Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olive Oil Polyphenols and Cardiovascular Health Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy|Normal Weight|Overweight|Obese
Interventions: DIETARY_SUPPLEMENT: High-polyphenol olive oil|DIETARY_SUPPLEMENT: Low-polyphenol olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare Two Formulations of LY3209590 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3209590 (Formulation 1)|DRUG: LY3209590 (Formulation 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apatinib and Camrelizumab in Recurrent or Metastatic Nasopharyngeal Carcinoma With First-line Treatment Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma|Recurrent Nasopharyngeal Carcinoma|Metastatic Nasopharyngeal Carcinoma|Chemotherapy Effect|Immunotherapy|Molecular Targeted Therapy
Interventions: DRUG: Apatinib plus Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Lay Navigators in Meeting Cancer Patients' Non-Clinical Needs: A Pilot Study
Status: COMPLETED
Conditions: Breast Cancer|Gynecologic Cancer|Neck Cancer|Head and Neck Cancer|Gastrointestinal Cancer|Thoracic Cancer|Cutaneous Tumor|Urologic Cancer|Neurologic Cancer|Lymphoma|Sarcoma|Bone Marrow Transplant
Interventions: OTHER: Lay Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of RO5190591 (Danoprevir) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: ketoconazole|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
Status: COMPLETED
Conditions: Muscle Loss in Elderly
Interventions: DIETARY_SUPPLEMENT: Protein drink|DIETARY_SUPPLEMENT: placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up of Immunogenicity of a Single Dose of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Toddlers
Status: COMPLETED
Conditions: Encephalitis|Japanese Encephalitis
Interventions: OTHER: Blood sample|BIOLOGICAL: JE-CV administered in Study JEC02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Actions for Empowered Maternal Neonatal Care (ACUNE): A Nursing Intervention
Status: UNKNOWN
Conditions: Patient Empowerment
Interventions: BEHAVIORAL: Actions for Empowered Maternal Neonatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Effect of Vaginal Misoprostol With Dinoprostone in Term Pregnancies
Status: UNKNOWN
Conditions: Preeclampsia|Fetal Death|Fetal Membranes, Premature Rupture
Interventions: DRUG: misoprostol|DRUG: dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Therapy for Onychomycosis Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Onychomycosis of Toenail
Interventions: DEVICE: Single wavelength light (red) only|DEVICE: Dual wavelength light (red/blue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Scaffolds for Treatment of Gingival Recession Associated With Interproximal Tissue Deficiency
Status: UNKNOWN
Conditions: Recession|Periodontal Diseases
Interventions: PROCEDURE: Bone regeneration|DEVICE: Collagen membrane|DEVICE: Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Indo-Mediterranean Diet on Hepatic Steatosis and Fibrosis in NAFLD Children
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Indo Mediterranean diet|OTHER: Calorie restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freeze-dried vs Fresh Fecal Microbiota Transplantation in Patients With Slow Transit Constipation
Status: UNKNOWN
Conditions: Slow Transit Constipation
Interventions: PROCEDURE: Freeze-dried, Capsulized FMT|PROCEDURE: Fresh FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flexible Ureteroscopy on Renal Blood Flow
Status: COMPLETED
Conditions: Circulatory; Change
Interventions: PROCEDURE: flexible ureteroscopy|DEVICE: Doppler Ultrasound examination|DEVICE: laser lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PROFIL Study to Investigate the Effect of GPB on NfL Levels in Patients With Corticobasal Syndrome (CBS)
Status: RECRUITING
Conditions: Corticobasal Syndrome (CBS)
Interventions: DRUG: RAVICTI 1.1 g/ml|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT