pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Electrical Cardioversion, Ablation or Pace and Ablate for Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation|PROCEDURE: Pacemaker and AV node ablation|PROCEDURE: DC Cardioversion|DEVICE: Implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer
Status: TERMINATED
Conditions: Advanced Clear Cell Renal Cell Carcinoma|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer|Metastatic Clear Cell Renal Cell Carcinoma
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Ileostomy Patients
Status: COMPLETED
Conditions: Healthy|Ileostomy
Interventions: BEHAVIORAL: absorption and conversion of beta-carotene in human gastrointestinal (GI) tract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis
Status: NOT_YET_RECRUITING
Conditions: Vulvovaginal Candidiasis
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailoring OT and RD Services for Home-delivered Meal Clients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diet, Food, and Nutrition|Accidental Fall|Diabetes Mellitus|Heart Diseases
Interventions: BEHAVIORAL: Meals + RD services only|BEHAVIORAL: Meals + OT services only|BEHAVIORAL: Meals + RD + OT services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Namenda (Memantine) for Non-motor Symptoms in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Memantine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ADSTEM Inj. in Patients With Moderately Subacute and Chronic Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: ADSTEM Inj. (Adult human mesenchymal stem cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized, Parallel-group, Placebo-controlled Study to Evaluate Efficacy of CMS008618 for Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DEVICE: ColdZyme|DEVICE: ColdZyme Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 3-years Follow-up
Status: UNKNOWN
Conditions: Schizophrenia|Psychotic Disorders|Psychosis
Interventions: DRUG: Aripiprazole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the New Defocus Spectacle Lens in Preventing Progression of Myopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: OTHER: New defocus spectacle lenses|OTHER: Convenional aspheric single-vision spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Benefits of a Painless Lancing Device Among Diabetes Patients
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: Genteel lancing device|DEVICE: Conventional lancing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: BMS-690514|DRUG: Lapatinib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Dexmedetomidine and Long-term Survival After Cancer Surgery
Status: RECRUITING
Conditions: Elderly|Cancer Surgery|Dexmedetomidine|Long-Term Survivors
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Surgical Injection Lumbar Erector Spinae Plane Block
Status: COMPLETED
Conditions: Lumbar Spine Instability|Lumbar Spinal Stenosis|Lumbar Spine Degeneration
Interventions: DRUG: Surgical ESPB|DRUG: US guided ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
Status: RECRUITING
Conditions: Shoulder Surgery|Shoulder Pain|Shoulder Injuries|Shoulder Arthritis|Shoulder Disease|Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Arthropathy of Left Shoulder|Rotator Cuff Arthropathy of Right Shoulder|Rotator Cuff Repair
Interventions: DIAGNOSTIC_TEST: Ultrasound|DRUG: Ropivacaine|DRUG: Bupivacaine|DEVICE: MediPines AGM100 Advanced Respiratory Monitoring System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aliskiren Effect on Aortic Plaque Progression
Status: TERMINATED
Conditions: Atherosclerosis
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistive Exercise Versus HIIT on Calcium and Vitamin D
Status: ENROLLING_BY_INVITATION
Conditions: Vitamin D Deficiency|Calcium|Premenopause
Interventions: OTHER: resistive exercise|OTHER: high intensity interval training|DIETARY_SUPPLEMENT: calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: Fuzuloparib , Abiraterone acetate and Prednisone|DRUG: Fuzuloparib Placebo， Abiraterone acetate and Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Wearable Exoskeleton for Functional Arm Training
Status: COMPLETED
Conditions: Stroke|Post-Stroke Hemiparesis
Interventions: OTHER: Gravity Elimination Alone|OTHER: Path Assistance Alone|OTHER: Path Assistance and Gravity Elimination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Glymphatic System|White Matter Disease|Pediatric Disorder|Perivascular Disease
Interventions: DIAGNOSTIC_TEST: Magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose Administration Under Fasting Conditions in Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide Liquid|DRUG: Enzalutamide Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: lerodalcibep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RMP-A03 Ocular Suspension in Patients With Pterygium
Status: ACTIVE_NOT_RECRUITING
Conditions: Pterygium
Interventions: DRUG: RMP-A03 - Dose 1|DRUG: RMP-A03 - Dose 2|DRUG: RMP-A03 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GQ1001 Combined With Pyrotinib for Treatment With HER2 Positive Metastatic Breast Cancer
Status: RECRUITING
Conditions: Advanced/ Metastatic Her-2 Positive Breast Cancer
Interventions: DRUG: GQ1001+pyrotinib|DRUG: pyrotinib+capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spinal Column Flexion on Unilaterality of Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures|Spinal Anesthesia
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Study in Adolescent and Adult Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: Primatene Mist|DRUG: Epinephrine inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib and Stem Cell Transplant for Plasma Cell Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma|Leukemia, Plasma Cell
Interventions: DRUG: Carfilzomib|DRUG: Melphalan|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication Study in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Helicobacter Pylori Infection
Interventions: DRUG: Helicobacter pylori eradication therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases
Status: COMPLETED
Conditions: Clear-Cell Metastatic Renal Cell Carcinoma|Non Small Cell Lung Cancer Metastatic|Brain Metastases, Adult|Small Cell Lung Cancer|Melanoma
Interventions: DRUG: Nivolumab|RADIATION: Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulating Escape Using Focused Ultrasound
Status: RECRUITING
Conditions: Anxiety Disorders
Interventions: DEVICE: Active transcranial focused ultrasound (tFUS)|DEVICE: Sham transcranial focused ultrasound (tFUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobilization With Movement Technique on the Stiffness of Cervical Muscles in Individuals With Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Mobilisation with movement|OTHER: Sham mobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Residual Effect of Chlorhexidine-alcohol Compared to Triclosan-alcohol
Status: COMPLETED
Conditions: Infectious Diseases
Interventions: OTHER: Bacterial culture of the prepared skin's areas with two antiseptics and two controls|OTHER: Preparing skin's areas to be tested with two antiseptics and two controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus Type 1
Interventions: BIOLOGICAL: Stem Cell Educator Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Whether Ide-cel (bb2121) Can Be Made From People With Multiple Myeloma Who Have Had a Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Ide-cel (bb2121)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Treatment With Doxycycline to Enhance the Durability of Endovascular Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Aortic Aneurysm
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Subarachnoid Administrations of Adults Autologous Mesenchymal Stromal Cells in SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Adult Autologous Mesenchymal Bone Marrow Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Altrazeal™ Versus Aquacel® Ag for Partial Thickness Skin Donor Sites
Status: COMPLETED
Conditions: Partial-thickness Skin Donor Sites
Interventions: DEVICE: Altrazeal|DEVICE: Aquacel Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIG for Infection Prevention After CAR-T-Cell Therapy
Status: RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: Immune Globulin Infusion (Human), 10% Solution|BIOLOGICAL: Anti-CD19 CAR T Cells Preparation|OTHER: Saline|PROCEDURE: Biospecimen Collection|OTHER: Survey Administration|OTHER: Electronic Health Record Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Responses to Autologous Langerhans-type Dendritic Cells Electroporated With mRNA Encoding a Tumor-associated Antigen in Patients With Malignancy: A Single-arm Phase I Trial in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Langerhans-type dendritic cells (a.k.a. Langerhans cells or LCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Efficacy of Ergothioneine to Delay Cognitive Decline
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: ergothioneine|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Aortic Valve Implantation Versus Standard Surgical Aortic Valve Operation
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosthesis Survival|Prosthesis; Cardiac, Heart, Functional Disturbance as Result
Interventions: DEVICE: Transcatheter Aortic Valve Implantation|PROCEDURE: Bioprothesis|PROCEDURE: Sutureless
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Valproic Acid and Radiation Therapy for Rectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: RADIATION: preoperative radiation therapy|DRUG: Valproic Acid|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: Magnetic resonance relaxometry|DIAGNOSTIC_TEST: Magnetic resonance spectroscopy|DIAGNOSTIC_TEST: Blood Draw|DIAGNOSTIC_TEST: DXA|DIAGNOSTIC_TEST: pQCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of the SMA During Unimanual and Bimanual Movements Preparation: the Mirror Movements Paradigm
Status: COMPLETED
Conditions: Congenital Mirror Movements
Interventions: OTHER: Healthy volunteers|OTHER: Congenital mirror movements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Corticosteroid-induced Glucose Intolerance
Status: UNKNOWN
Conditions: Glucose Intolerance
Interventions: DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN)
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: DRUG: Tenecteplase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of EpiCept™ NP-1 Topical Cream vs. Oral Gabapentin in Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Post Herpetic Neuralgia|PHN|Neuropathy|Nerve Pain
Interventions: DRUG: EpiCept-NP-1 Cream|DRUG: Gabapentin Capsules|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Frailty on Blood Biology Indicators, Quality of Life and Survival of Patients With Radical Prostatectomy
Status: NOT_YET_RECRUITING
Conditions: Prostatic Neoplasms|Frailty|Blood Biological Indicators|Quality of Life|Survival
Interventions: OTHER: frailty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ticagrelor And Clopidogrel on Inflammatory Biomarkers And Vascular Endothelial Function
Status: UNKNOWN
Conditions: ST-Segment Elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Genotype 2 or 3 Patients With Chronic Hepatitis Virus Infection
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: Placebo|DRUG: Daclatasvir|DRUG: Pegylated interferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Two-Way Crossover Fed Bioequivalence Study of Nabumetone 750 mg Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nabumetone 750 mg tablets, single dose|DRUG: Nabumetone 750 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Sequentially Applied Repetitive Transcranial Magnetic Stimulation in Obsessive- Compulsive Disorders
Status: COMPLETED
Conditions: Obsessive-compulsive Disorder
Interventions: DEVICE: repetitive transcranial magnetic stimulation (Magstim rapid magnetic stimulator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mechanical Insufflation-exsufflation on Respiratory Parameters in Two Neuromuscular Populations.
Status: COMPLETED
Conditions: Mechanical Insufflation-exsufflation Session ( With Cough Assist)
Interventions: DEVICE: Plethysmography opto electronic|PROCEDURE: respiratory parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: inStability Treated With Ligament RecOnstruction Augmented With iNternal bracinG
Status: RECRUITING
Conditions: Ankle Sprains|Talofibular; Sprain (Strain)
Interventions: PROCEDURE: Internal Brace augmented ankle Ligament reconstruction|PROCEDURE: Brostrom-Gould ankle Ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind Study to Assess Paclitaxel-eluting Stents in Treatment of Longer Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Express Paclitaxel-Eluting Coronary Stent System|DEVICE: Control stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Versus Approved Methyl-aminolevulinate Photodynamic Therapy (MAL-PDT) Regime in Basal Cell Carcinoma (BCC)
Status: COMPLETED
Conditions: Skin Neoplasms|Carcinoma, Basal Cell
Interventions: DRUG: MAL-PDT re-treatment|DRUG: usual MAL-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diesel Exhaust and Mechanism of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine|OTHER: Diesel exhaust|OTHER: Filtered air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Circulating Tumor Cells and Tumor DNA in HCC and NET
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Neuroendocrine Tumors
Interventions: DRUG: Sorafenib|PROCEDURE: Radiofrequency ablation (RFA) or surgery|DRUG: Everolimus|DRUG: Lanreotide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Loss of Resistance, w/wo Stimulation, For Epidural Placement
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Thoracic epidural block|PROCEDURE: Electrical Nerve stimulation|DRUG: Solution For Thoracic epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of MG7 Redirected Autologous T Cells for Advanced MG7 Positive Liver Metastases(MG7-CART)
Status: UNKNOWN
Conditions: Liver Metastases
Interventions: BIOLOGICAL: MG7-CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening While You Wait 2: Alcohol and Tobacco Use
Status: UNKNOWN
Conditions: Alcohol; Harmful Use|Tobacco Use|Tobacco Use Cessation|Alcohol Use, Unspecified
Interventions: BEHAVIORAL: Behavioral: Usual care plus eToolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Attitudes and Decision-making After Pregnancy Testing Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Unintended Pregnancy|Undesired Pregnancy
Interventions: OTHER: Pregnancy preferences (Aim 1)|OTHER: Sociocultural environment (Aim 2)|OTHER: Pregnancy preferences (Aim 3a)|OTHER: Pregnancy (Aim 3b)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: sacubitril/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine
Status: COMPLETED
Conditions: Bacteriuria, Intermittent Catheterization
Interventions: DEVICE: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Downsizing of Unresectable Cholangiocarcinoma by Combined Intravenous and Intra-arterial Chemotherapy
Status: COMPLETED
Conditions: Cholangiocellular Carcinoma
Interventions: DRUG: Selective intra-arterial floxuridine and systemic gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Overweight/Obesity With Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Light-Fat Rice® combined with Active Peptide®+ lifestyle guidance|DIETARY_SUPPLEMENT: A staple food of comparable energy containing a small amount of dietary fiber combined with a comparable energy maltodextrin + lifestyle guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of and Engagement in a Mobile Exergame With Tailored Feedback
Status: COMPLETED
Conditions: Physical Activity|Health Behavior
Interventions: BEHAVIORAL: 'SmartLife' with tailored feedback|BEHAVIORAL: 'SmartLife' without tailored feedback|BEHAVIORAL: No game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cholestasis Reversal: Efficacy of IV Fish Oil
Status: COMPLETED
Conditions: Parenteral Nutrition Associated Liver Disease|Short Bowel Syndrome|Gastrointestinal Disease
Interventions: DRUG: Omegaven®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics of MTX-101 in Healthy Adults and Patients
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers|Celiac Disease|Type 1 Diabetes
Interventions: DRUG: Placebo|DRUG: MTX-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "NSAIDs vs. Opiates: Which is More Effective in Managing Pain in Mild to Moderate Acute Pancreatitis?
Status: RECRUITING
Conditions: Acute Pancreatitis
Interventions: DRUG: Ketorolac|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Effects of Mirror Therapy in Patients With Complex Regional Pain Syndrome (CRPS) Type 1
Status: COMPLETED
Conditions: Complex Regional Pain Syndrome Type I
Interventions: BEHAVIORAL: mirror therapy|BEHAVIORAL: Routine physical therapy and exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2
Status: COMPLETED
Conditions: Otitis Media With Effusion in Children|Otitis Media Recurrent
Interventions: DRUG: EXE844 Sterile Otic Suspension, 0.3%|PROCEDURE: Tympanostomy Tube Insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Exercise|Walking Pneumonia|Diabetes
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Evaluation of the Activity of a Cosmetic Product (Topical Use) on Hair Regrowth vs Placebo
Status: COMPLETED
Conditions: Hypertrichosis
Interventions: OTHER: Actapil Corpo Spray (SHEDIR PHARMA Srl - Italy)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Iron Isomaltoside 1000 Administration on Hemoglobin Concentration in Patients Undergoing Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Aortic Stenosis (Treated With TAVI)
Interventions: DRUG: Normal saline|DRUG: Iron isomaltoside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Breast Carcinoma|HER2-Positive Breast Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|HER2-positive Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Denifanstat|DRUG: Exemestane|DRUG: Fulvestrant|PROCEDURE: Echocardiography|DRUG: Letrozole|DRUG: Paclitaxel|BIOLOGICAL: Trastuzumab|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of DW-1401 in Acute and Chronic Gastritis Patients
Status: COMPLETED
Conditions: Gastritis Acute|Gastritis Chronic
Interventions: DRUG: Test(DW1401)|DRUG: Reference(Stillen tab.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Do Apolipoprotein E Polymorphisms Influence Risk of Cognitive Decline by Modulating Omega-3 Fatty Acid Metabolism?
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of TA-7284 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TA-7284 Low|DRUG: TA-7284 High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Inactivated and Live Polio Vaccines
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Group A: Trivalent Oral Polio Vaccine|BIOLOGICAL: Group B: Bivalent Oral Polio Vaccine|BIOLOGICAL: Group C: Inactivated Polio Vaccine|BIOLOGICAL: Group D: fractional IPV (f-IPV)|BIOLOGICAL: Arm E: f-IPV and bOPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Status: RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Larotrectinib|PROCEDURE: Larotrectinib surgical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Real-time Ultrasound-CT Fusion Imaging and Ultrasound-guided Selective Lumbar Nerve Root Block
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: real-time ultrasound-CT fusion imaging|PROCEDURE: ultrasound alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Insulin Detemir and Insulin Glargine in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin detemir|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
Status: RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Rocatinlimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROTECT : Pacing to Protect Heart for Damage From Blocked Heart Vessel and From Re-opening Blocked Vessel(s)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Temporary RV VVI pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activation Intervals Effects on Non-surgical Maxillary Expansion in Adults
Status: UNKNOWN
Conditions: Maxillary Anomaly
Interventions: PROCEDURE: semirapid maxillary expansion (SRME)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Folfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride Liposome, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: bortezomib|DRUG: dexamethasone|DRUG: pegylated liposomal doxorubicin hydrochloride|GENETIC: protein analysis|OTHER: immunologic technique
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Transplantation in the Treatment of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells transplantation|DRUG: drug therapy according to Vietnamese MOHS procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Baromètre Santé Adulte 2021-2022
Status: SUSPENDED
Conditions: Diabetes|Hypercholesterolemia|Renal Failure|Dengue Fever|Zika|Chikungunya|Ross River|Malaria|SARS-CoV Infection|Chronic Disease
Interventions: BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Inhaled Insulin in Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: inhaled human insulin|DRUG: insulin detemir|DRUG: insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery
Status: TERMINATED
Conditions: Pelvic Organ Prolapse|Abdominal Surgery|Laparoscopic Surgery|Post Operative Pain
Interventions: DEVICE: Abdominal binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lifestyle Intervention Versus Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Diabetes Mellitus|Hypertension
Interventions: PROCEDURE: Bariatric surgery|BEHAVIORAL: Intensive lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 99mTc-CNDG SPECT/CT in Brain Tumors
Status: NOT_YET_RECRUITING
Conditions: Intracranial Tumor
Interventions: DIAGNOSTIC_TEST: 99mTc-CNDG SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Triple Tourniquets With or Without Tranexamic Acid for Reducing Blood Loss at Open Myomectomy
Status: UNKNOWN
Conditions: Myoma
Interventions: PROCEDURE: Triple tourniquets|DRUG: TA|OTHER: placebo to TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: External Beam Radiation Therapy (EBRT) With or Without Hormonal Therapy in Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Radiation Therapy|DRUG: Bicalutamide|DRUG: Leuprolide|DRUG: Goserelin|DRUG: Flutamide|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Weekly Motexafin Gadolinium (MGd) for Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Leukemia|Lymphoma
Interventions: DRUG: motexafin gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Central Nervous System (CNS) Stem Cells Transplantation in Pelizaeus-Merzbacher Disease (PMD) Subjects
Status: COMPLETED
Conditions: Pelizaeus-Merzbacher Disease
Interventions: BIOLOGICAL: HuCNS-SC cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Refralon in Patients With Recurrence Paroxysmal and Persistent Forms of Atrial Fibrillation Who Underwent Catheter Ablation
Status: RECRUITING
Conditions: Atrium; Fibrillation|Atrium; Flutter
Interventions: DRUG: Pharmacological cardioversion with Refralon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Hypnosis Before External Cephalic Version (ECV)
Status: UNKNOWN
Conditions: Breech Presentation at Term
Interventions: OTHER: Clinical hypnosis or neuro-linguistic programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curcuminoids and Contrast-induced Acute Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury|Contrast Media Toxicity|Curcuminoid|Chronic Kidney Diseases
Interventions: DRUG: Curcuminoid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia|Memory Impairment|Cognitive Impairment
Interventions: BEHAVIORAL: RDAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-201 Clinical Trial
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: ALLO-ASC-DFU|OTHER: Standard therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inqovi Maintenance Therapy in Myeloid Neoplasms
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Stem Cell Leukemia
Interventions: DRUG: Inqovi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infection Control in ERCP Using a Duodenoscope With a Disposable Cap
Status: COMPLETED
Conditions: Bile Duct Diseases
Interventions: DEVICE: ERCP procedure with Pentax ED-34i10T2 Duodenoscope with Disposable Cap (DEC)|DEVICE: ERCP procedure with Pentax ED-34i10T Duodenoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy in Treating Patients With Metastatic Cancer
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Head and Neck Cancer|Liver Cancer|Lung Cancer|Metastatic Cancer|Ovarian Cancer|Pancreatic Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: CEA RNA-pulsed DC cancer vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Panax Ginseng and Salvia Miltiorrhiza Supplementation on Vascular Function
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Eccentric exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: spinosad topical suspension, 0.9%|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxia Imaging -Guided Radiotherapy of Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: FMISO-PET/CT|RADIATION: FDG-PET/CT|RADIATION: contrast-enhanced CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: 3 day fast|OTHER: 3 day CHO-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid
Status: RECRUITING
Conditions: Obesity|Diabetes Mellitus, Type 2
Interventions: OTHER: Large liquid meal, spinal catheter and venous line
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Treatment Effects of Tooth Borne Versus Bone-anchored Protraction Procedures in Class III Patients With Maxillary Deficiency
Status: UNKNOWN
Conditions: Anterior Crossbite|Class III Malocclusion|Maxillary Deficiency
Interventions: OTHER: Face mask with hybrid-hyrax|OTHER: Face mask with conventional bonded RME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Effect of Trimodal Prehabilitation Compared to ERAS in Colorectal Cancer Surgery.
Status: SUSPENDED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Trimodal rehabilitation + ERAS|PROCEDURE: ERAS + nutritional prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Meningococcal B Recombinant Vaccine When Administered Concomitantly With Routine Vaccines to Healthy Infants of 2 Months of Age and Older, in Taiwan.
Status: COMPLETED
Conditions: Meningococcal Disease|Infections, Meningococcal
Interventions: BIOLOGICAL: Bexsero®|BIOLOGICAL: Routine vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen Vaccine and Nivolumab in Treating Patients With Recurrent Glioblastoma
Status: WITHDRAWN
Conditions: Giant Cell Glioblastoma|Gliosarcoma|Oligodendroglioma|Recurrent Glioblastoma|Small Cell Glioblastoma
Interventions: BIOLOGICAL: autologous dendritic cells pulsed with tumor lysate antigen Vaccine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Use & Infections in ViEtnam: Mental Health Intervention for INjecting Drug Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychiatric Disorder|Drug Use
Interventions: OTHER: Community-based psychiatric intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH