pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long-Term Safety Study of GS-6624 in Adults With Idiopathic Pulmonary Fibrosis (IPF)
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Simtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Platelet-Rich Plasma in the Management of Asherman Syndrome
Status: COMPLETED
Conditions: Intrauterine Adhesion
Interventions: BIOLOGICAL: platelet rich plasma|COMBINATION_PRODUCT: amniotic membrane graft group|DEVICE: Intrauterine balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Resistive Capacitive Monopolar Radiofrequency in the Physiotherapeutic Treatment of Chronic Pelvic Pain: RCT
Status: COMPLETED
Conditions: Pelvic Pain|Pelvic Pain Syndrome|Chronic Pain|Chronic Pain Syndrome|Chronic Pelvic Inflammatory Disease|Physical Therapy
Interventions: COMBINATION_PRODUCT: Active resistive capacitive monopolar radiofrequency with physiotherapeutic techniques and pain education|COMBINATION_PRODUCT: Inactive resistive capacitive monopolar radiofrequency with physiotherapeutic techniques and pain education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Access to Genetic Information Leveraging Innovative Technology (AGILITY)
Status: NOT_YET_RECRUITING
Conditions: Genetic Testing
Interventions: BEHAVIORAL: AGILITY (Access to Genetic Information Leveraging Innovative TechnologY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Status: COMPLETED
Conditions: Radiodermatitis|Breast Cancer
Interventions: DEVICE: Photobiomodulation therapy (PBMT)|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine Improves Post-Thoracotomy Analgesia
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: morphine|DRUG: morphine ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Arm Free Flap for Reconstruction of the Oral Cavity and Head and Neck Soft Tissue Defects.
Status: UNKNOWN
Conditions: Oral Cancer
Interventions: PROCEDURE: Lateral Arm Free Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
Status: COMPLETED
Conditions: Risk Behavior|Medication Adherence|HIV
Interventions: BEHAVIORAL: 3H+ (Holistic Health for HIV)|BEHAVIORAL: HHRP+ (Holistic Health Recovery Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Granulocytapheresis Plus Steroids vs Steroids Alone in Active Steroid Dependant Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DEVICE: Granulocyte Monocyte Apheresis (GMA-Apheresis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placing Preterm Infants in Polyethylene Bags Immediately After Birth
Status: UNKNOWN
Conditions: Newborn|Infant|Hypothermia|Premature
Interventions: OTHER: Polyethylene bag before the umbilical cord is clamped
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Ovarian Cancer, TNBC, SCLC, Other Solid Tumours
Interventions: DRUG: AZD 1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Denosumab and Actonel® in Post Menopausal Women Transitioned From Alendronate Therapy
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Actonel®|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Induced Constipation
Interventions: DRUG: naloxone|DRUG: oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Duloxetine vs Escitalopram in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Duloxetine|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: MTL-CEBPA|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Shoulder Arthroscopy Work
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: PROCEDURE: Arthroscopic Sub-acromial Decompression Surgery|PROCEDURE: Shoulder Arthroscopy|OTHER: Active Monitoring with Specialist Reassessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indirect Pulp Capping Using Biodentine and Theracal Light-cured in Primary Molars
Status: COMPLETED
Conditions: Pulp Caping|Biodentine|Theracal
Interventions: DRUG: Biodentine|DRUG: Theracal light cured
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone for Individuals of East Asian Descent
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical vs. Medical Treatment of Urge Urinary Incontinence in Women
Status: UNKNOWN
Conditions: Urge Urinary Incontinence
Interventions: DRUG: solifenacin|PROCEDURE: cesa/vasa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon
Status: TERMINATED
Conditions: Colonic Dysplasia|Adenomatous Polyps|Irritable Bowel Disease
Interventions: DEVICE: confocal endomicroscope|DRUG: Fluorescein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: KK2260|DRUG: KK2260
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial
Status: ENROLLING_BY_INVITATION
Conditions: Implementation Science|Heart Transplant|Decision Making|Bias, Racial|Health Equity|Bias, Sex
Interventions: BEHAVIORAL: SOCIAL HF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of rhPDGF as an Adjunct to Non-surgical Periodontal Therapy of Intrabony Defects
Status: NOT_YET_RECRUITING
Conditions: Periodontal Diseases|Periodontal Attachment Loss|Pocket, Periodontal|Intrabony Periodontal Defect
Interventions: PROCEDURE: SRP+rhPDGF|PROCEDURE: SRP+collagen sponge|PROCEDURE: SRP alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin phosphate|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischaemic Heart Disease|Ischemic Heart Disease
Interventions: PROCEDURE: Angiographic guided PCI|PROCEDURE: OCT guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mandibular Muscle Energy Technique in Patients With Mandibular Joint Pathology and Bruxism
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Bruxism|Pain Threshold|Kinesiophobia
Interventions: PROCEDURE: Muscle-energy mandibular technique|PROCEDURE: Sham technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Pelvic Floor Muscle Function: A Reliability and Correlation Study
Status: UNKNOWN
Conditions: Pelvic Floor Dysfunction
Interventions: DIAGNOSTIC_TEST: evaluation of pelvic floor muscle function through the PHENIX instrument|DIAGNOSTIC_TEST: vaginal palpation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chronic Lumbosacral Radiculopathy: Impact of an Analgesic Dietary Intervention on Pain & Function
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Diet A|OTHER: Diet B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer
Status: TERMINATED
Conditions: Estrogen Receptor-negative Breast Cancer|Extensive Stage Small Cell Lung Cancer|HER2-negative Breast Cancer|HER2-positive Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Recurrent Melanoma|Recurrent Non-small Cell Lung Cancer|Recurrent Small Cell Lung Cancer|Stage IV Breast Cancer|Stage IV Melanoma|Stage IV Non-small Cell Lung Cancer|Tumors Metastatic to Brain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Gamma-secretase/Notch signalling pathway inhibitor RO4929097|RADIATION: Whole-brain radiation therapy (WBRT)|RADIATION: Stereotactic radiosurgery (SRS)|PROCEDURE: Cognitive assessment|OTHER: Laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of HCP1303 and Co-administration of HGP1201, HIP1402 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Erectile Dysfunction|Prostatic Hyperplasia
Interventions: DRUG: HCP1303|DRUG: HGP1201|DRUG: HIP1402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women's Health Initiative (WHI)
Status: COMPLETED
Conditions: Bone Diseases|Breast Neoplasms|Cardiovascular Diseases|Colonic Neoplasms|Coronary Disease|Heart Diseases|Myocardial Ischemia|Osteoporosis|Postmenopause
Interventions: DRUG: hormone replacement therapy|DRUG: estrogens|DRUG: progestins|DRUG: estrogen replacement therapy|BEHAVIORAL: diet, fat-restricted|DRUG: calcium|DRUG: vitamin D|BEHAVIORAL: dietary supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Interactions of Quadruple Therapy With Anaprazole/Amoxicilin/Clarithromycin/Bismuth
Status: UNKNOWN
Conditions: Healthy Male Volunteers
Interventions: DRUG: Anaprazole Sodium|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Proprioceptive Stimulation Under Visual Feedback in Patient With CRPS
Status: UNKNOWN
Conditions: Complex Regional Pain Syndromes
Interventions: BEHAVIORAL: Usual Physiotherapy|DEVICE: Gloreha device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Oral antidiabetetic drugs|DRUG: Basal insulin|DRUG: Glucagon-like peptide-1 (GLP-1)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage
Status: RECRUITING
Conditions: Breast Cancer|BRCA Mutation
Interventions: DRUG: Tranexamic acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PNF and Shoulder Stabilization Exercises on Pain, QoL and Functionality in Patient With AC
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Proprioceptive Neuromuscular Facilitation (PNF)|OTHER: Shoulder Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Continuous Monitoring of Patients in and After the Acute Admission Ward to Optimize Clinical Pathways
Status: UNKNOWN
Conditions: Monitoring|Clinical Deterioration|Acute Disease
Interventions: DEVICE: Wearable Sensor|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia
Status: COMPLETED
Conditions: Thoracal Epidural Block
Interventions: PROCEDURE: Neuromuscular blocker usage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Iberdomide|DRUG: Oral Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Magnesium Supplementation on Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Oral Magnesium Supplementation|OTHER: Standard Care for diabetic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Exocrine Pancreatic Dysfunction in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Exocrine Pancreatic Insufficiency
Interventions: OTHER: Frequency of hypoglycemia in people with type 1 diabetes and exocrine pancreatic insufficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Purse string closure technique|PROCEDURE: Continuously locked closure technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEaling LIght Algorithms for the ICU Patient
Status: COMPLETED
Conditions: Critical Care|Phototherapy
Interventions: DEVICE: Dynamic Light Therapy Device, LSA-1|DEVICE: Dynamic Light Therapy Device, LSA-2|DEVICE: Dynamic Light Therapy Device, LSA, 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial RAdioembolization Versus ChemoEmbolization for the Treatment of Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TACE-DEB|DRUG: 90Y-RE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipedal vs. Unipedal Exercises in Chronic Ankle Instability
Status: RECRUITING
Conditions: Instability; Ankle (Ligaments) (Old Injury)
Interventions: OTHER: Early Bipedal Exercise|OTHER: Late Bipedal Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe Asthma, MepolizumaB and Affect: SAMBA Study
Status: RECRUITING
Conditions: Severe Eosinophilic Asthma|Psychological Distress|Anxiety|Depression|Psychological Stress|Psychological Adjustment|Psychological Disorder|Psychosocial Problem|Psychosocial Stressor|Psychological|Emotions|Emotional Disorder|Emotional Dysfunction|Emotional Distress|Adjustment|Adjustment, Emotional|Coping Behavior
Interventions: OTHER: no study intervention. Patients receive standard clinical care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 10% Lidocaine Spray for Intrauterine Device Insertion
Status: COMPLETED
Conditions: Contraception|Intrauterine Device
Interventions: DRUG: lidocaine spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cognitive Behavioural Therapy (CBT) for Children With Autistic Spectrum Disorders
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy|OTHER: Social Recreational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Face-to-Face and Internet-Based BBAT in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: BBAT (Basic Body Awareness Therapy)|BEHAVIORAL: Online BBAT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries
Status: TERMINATED
Conditions: Postoperative Pain Management
Interventions: DRUG: EXPAREL and Bupivacaine|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Memantine Versus Placebo on Ischemic Stroke Outcome
Status: COMPLETED
Conditions: Ischemic Stroke|Excitotoxicity|Memantine
Interventions: DRUG: Placebo|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Relatlimab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cetuximab(Erbitux) With Cisplatin and Capecitabine(Xeloda)as 1st Line Treatment in the Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: cetuximab, cisplatin, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Platelet Dysfunction|Cardiopulmonary Bypass
Interventions: DEVICE: Terumo|DEVICE: LivaNova
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.
Status: RECRUITING
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Direct Laryngoscopes for Tracheal Intubation in Patients Undergoing Lumbar Spine Surgery
Status: TERMINATED
Conditions: Anesthesia|Airway
Interventions: DEVICE: Blade MAC size 3|DEVICE: Blade MAC size 3.5|DEVICE: Inscope Blade size 3.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Detection of Exhaled Methane Levels in Hemorrhagic Shock
Status: UNKNOWN
Conditions: Hemorrhagic Shock|Trauma
Interventions: DIAGNOSTIC_TEST: Measurement of methane concentrations in exhaled breath|DIAGNOSTIC_TEST: Videomicroscopy of the sublingual microcirculation|DIAGNOSTIC_TEST: Blood gas and laboratory analysis|DIAGNOSTIC_TEST: Hemodynamic monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ranolazine and Microvascular Angina by PET in the Emergency Department
Status: COMPLETED
Conditions: Microvascular Angina
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Upgrade to Invasive Cancer in Patients Diagnosed With Ductal Carcinoma in Situ by Percutaneous Core Needle Biopsy
Status: COMPLETED
Conditions: Carcinoma, Ductal, Breast|Invasive Breast Cancer|IMAGE
Interventions: DIAGNOSTIC_TEST: contrast-enhanced breast MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Placebo-controlled Trial of Inhaled iNO in Acute ST-segment Elevation MI Treated by Primary Angioplasty
Status: COMPLETED
Conditions: STEMI
Interventions: PROCEDURE: inhaled nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Video NET With CYP Who Witnessed Domestic Violence
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder in Children|Post-Traumatic Stress Disorder in Adolescence|Post-Traumatic Stress Disorder Complex|Domestic Violence|Trauma, Psychological|Narrative Exposure Therapy
Interventions: OTHER: Narrative Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist®
Status: COMPLETED
Conditions: Pharmacokinetics|MRI|Liver|Drug Transporter|Gd-EOB-DTPA
Interventions: DRUG: Primovist® 0,25 mmol/ml solution for injection|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent Grade 3b Follicular Lymphoma|Recurrent Primary Mediastinal Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Refractory Grade 3b Follicular Lymphoma|Refractory Primary Mediastinal Large B-Cell Lymphoma|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Lisocabtagene Maraleucel|DRUG: Polymer-conjugated IL-15 Receptor Agonist NKTR-255|PROCEDURE: X-Ray Imaging|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Lumbar Puncture|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Masked, Placebo Controlled, Single Center, Randomized Clinical Trial to Assess the Safety and Efficacy of Subjects With Mild Asthma Induced by the Bronchial Allergen Challenge (BAC)
Status: COMPLETED
Conditions: Atopic Asthma
Interventions: DRUG: ADX-629|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue and Functional Assessment of Myocardial Injury in Hodgkin Lymphoma (HL) Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma Survivor
Interventions: OTHER: Clinical Assessment|PROCEDURE: Stress cardiac MRI|PROCEDURE: Stress echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients
Status: COMPLETED
Conditions: Mechanical Ventilation|Dexmedetomidine|Midazolam|Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Fentanyl|DEVICE: Indirect calorimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Steerable Delivery Sheaths on Successful Closure of LA A With AMULET
Status: UNKNOWN
Conditions: Atrial Fibrillation|Stroke
Interventions: OTHER: Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea|Obesity Hypoventilation Syndrome (OHS)|Chronic Obstructive Pulmonary Disease (COPD)|Neuromuscular Diseases (NMD)
Interventions: DEVICE: Non-Invasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two WeChat Mini Program-based Interventions Reducing Sexual Risk Behaviors Among Heterosexual Male Factory Workers
Status: RECRUITING
Conditions: Behavior, Sex
Interventions: BEHAVIORAL: WeChat Mini Program plus tailored online health promotion videos|BEHAVIORAL: WeChat Mini Program Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Japanese Participants With Primary Advanced or Recurrent Endometrial Cancer
Status: RECRUITING
Conditions: Carcinoma
Interventions: BIOLOGICAL: Dostarlimab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electromechanical Gait Trainer in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DEVICE: Gait trainer treatment|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LongShengZhi Capsule on Functional Recovery After Acute Ischaemic Stroke (LONGAN)
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: LongShengZhi capsule|DRUG: LongShengZhi capsule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Five Versus Six Fractions Per Week for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Accelerated Radiotherapy Fractionation|RADIATION: Accelerated Radiotherapy Fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CDP7657 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Immune System Diseases|Autoimmune Diseases|Lupus Erythematosus, Systemic|Skin and Connective Tissue Diseases|Connective Tissue Disease
Interventions: BIOLOGICAL: CDP7657|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of Multiple Subcutaneous Injections of Various Doses of BCD-085 in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: BCD-085|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deciphering the Impact of Exposures From the Gut Microbiome-derived Molecular Complex in Human Health and Disease
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Parkinson Disease|Healthy
Interventions: OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Single dose of PF-07220060 as first Tablet Formulation|DRUG: Single dose of PF-07220060 as second Tablet Formulation|DRUG: Single dose of PF-07220060 as first Tablet Formulation|DRUG: Single dose of PF-07220060 as second Tablet Formulation|DRUG: Single dose of PF-07220060 as a Tablet Formulation|DRUG: Single dose of PF-07220060 as a Tablet formulation under Rabeprazole administration|DRUG: Single dose of PF-07220060 as a Tablet formulation under Rabeprazole administration|DRUG: Single dose of PF-07220060 as third tablet formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
Status: COMPLETED
Conditions: Fall Patients|Delirium|Quality of Life|Functional Status
Interventions: OTHER: Geriatric Screening tools
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Patient Satisfaction for Digital Versus Conventional Maxillary Obturator
Status: COMPLETED
Conditions: Maxillofacial Prosthesis User
Interventions: OTHER: conventional obturator|OTHER: 3 d printed obturator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lidocaine on Smooth Emergence With Double Lumen Tube
Status: UNKNOWN
Conditions: Cough|Lidocaine
Interventions: DRUG: Lidocaine Iv|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: How Effect Olive Oil and Eoprotin on Immunological Parameters and Growth
Status: UNKNOWN
Conditions: Breast Milk Expression|Premature Birth of Newborn
Interventions: DIETARY_SUPPLEMENT: olive oil|DIETARY_SUPPLEMENT: Eoprotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: PEP005 Gel - Biological Effects in Actinic Keratosis Assessed by Histology
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 (Ingenol mebutat Gel, 0.05 %)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Mesenchymal Stromal Cells|Psoriasis|Drug Effect|Drug Toxicity
Interventions: DRUG: Calcipotriol ointment|BIOLOGICAL: adipose-derived multipotent mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ad26.COV2.S Administered as Booster Vaccination in Adults Who Have Previously Received Primary Vaccination With Ad26.COV2.S or BNT162b2
Status: COMPLETED
Conditions: Coronavirus Disease
Interventions: BIOLOGICAL: Ad26.COV2.S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042)
Status: COMPLETED
Conditions: Hypercholerolemia
Interventions: DRUG: MK0653; ezetimibe / Duration of Treatment: 12 weeks|DRUG: Comparator: simvastatin / Duration of Treatment: 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Response to BCG Vaccination in Neonates Born to HIV and LTBI Infected and Non-infected Mothers
Status: COMPLETED
Conditions: HIV Infections|Neonatal Infection|LTBI - Latent Tuberculosis Infection|Immune Tolerance
Interventions: OTHER: RNAseq
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Docosahexaenoic (DHA) Values in Patients With Polycystic Ovary Syndrome (PCOS)
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DIAGNOSTIC_TEST: DHA levels of blood and cervical mucus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Arthritis|Immune-related Adverse Event
Interventions: DRUG: Adalimumab|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Response to Exercise in Women on Antiresorptive Medications
Status: TERMINATED
Conditions: Osteoporosis|Bone Loss
Interventions: OTHER: Progressive Resistance and Impact Exercise|OTHER: Static Balance and Postural Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: LX7101 (0.125%)|DRUG: LX7101 (0.25%)|DRUG: LX7101 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Brief Mindful Drinking/Eating Intervention for Hemodialysis Patients With Fluid Restrictions
Status: COMPLETED
Conditions: Kidney Failure|Quality of Life|Fluid Restriction|Interdialytic Weight Gain|Hemodialysis|Mindfulness
Interventions: BEHAVIORAL: Mindful Drinking/Eating Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IV Clinical Study of Recombinant Mycobacterium Tuberculosis Fusion Protein
Status: ACTIVE_NOT_RECRUITING
Conditions: Latent Tuberculosis Infection
Interventions: BIOLOGICAL: Recombinant Mycobacterium tuberculosis fusion protein for injection|BIOLOGICAL: TB-PPD was injected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Strategies Towards Personalised Treatment in Juvenile Idiopathic Arthritis (JIA).
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Triamcinolone Hexacetonide 20 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery Kinetics After Different Sprint Training Protocols (STRecovery)
Status: COMPLETED
Conditions: Sprint Training
Interventions: OTHER: Unresisted sprint training|OTHER: Resisted sprint training with load equal to 10% of body weight|OTHER: Resisted sprint training with load equal to 20% of body weight|OTHER: Control trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: 2-week dc of MTX and Influenza Vaccination in RA
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Influenza|Methotrexate
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Efficacy of Vibrabot Capsule and Polyethylene Glycol for Chronic Functional Constipation
Status: RECRUITING
Conditions: Chronic Functional Constipation
Interventions: DEVICE: Vibrabot capsule|DRUG: polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
Status: COMPLETED
Conditions: Hereditary Angioedema|Hereditary Angioedema Type I|Hereditary Angioedema Type II|Hereditary Angioedema Types I and II|Hereditary Angioedema Attack|Hereditary Angioedema With C1 Esterase Inhibitor Deficiency|Hereditary Angioedema - Type 1|Hereditary Angioedema - Type 2|C1 Esterase Inhibitor Deficiency|C1 Inhibitor Deficiency
Interventions: DRUG: Deucrictibant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Citicoline in Youth Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Citicoline (cytidine diphosphate-choline)|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Afatinib to Treat Lung Cancer Patients
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Afatinib (BIBW 2992)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate and stable statin therapy|DRUG: Stable statin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Preoxygenation by Supraglottic Jet Ventilation Before Endotracheal Intubation
Status: UNKNOWN
Conditions: Preoxygenation
Interventions: DEVICE: supraglottic jet ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: ACP-196|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Dose Combination of Desloratadine / Prednisolone in the Treatment of Moderate Severe Allergic Rhinitis in Children
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: DRUG: Desloratadine , Prednisolone|DRUG: Desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establishment of Social Skills Training Group in Adolescents With Autism Spectrum Disorder and Effectiveness Analysis
Status: COMPLETED
Conditions: Autism Spectrum Disorder High-Functioning
Interventions: BEHAVIORAL: PEERS® Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic Arthropathy
Status: TERMINATED
Conditions: Hemophilic Arthropathy
Interventions: DRUG: TRM-201 (Rofecoxib)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study
Status: ENROLLING_BY_INVITATION
Conditions: SCI - Spinal Cord Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Fluorouracil Before Surgery in Treating Patients With Primary or Recurrent Bile Duct Cancer
Status: TERMINATED
Conditions: Extrahepatic Bile Duct Cancer|Liver Cancer
Interventions: DRUG: fluorouracil|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparing an Operation to Monitoring, With or Without Endocrine Therapy (COMET) Trial For Low Risk DCIS
Status: ACTIVE_NOT_RECRUITING
Conditions: DCIS|Ductal Carcinoma in Situ
Interventions: OTHER: Surgery|OTHER: Active Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Altering Magill Forceps Affect Nasal Intubation Time
Status: COMPLETED
Conditions: Nasal Intubation|Dental Surgery|Pediatrics
Interventions: DEVICE: Intubation with Magill forceps|DEVICE: Intubation with altered Magill forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study of Setipiprant Tablets in Androgenetic Alopecia in Males
Status: COMPLETED
Conditions: Alopecia
Interventions: DRUG: Setipiprant|DRUG: Placebo|DRUG: Finasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Real-world Usage and Effectiveness of Elocta and Alprolix in Patients With Haemophilia A or B
Status: COMPLETED
Conditions: Haemophilia A|Haemophilia B
Interventions: DRUG: ELOCTA|DRUG: ALPROLIX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does VNS Interact With the Serotonergic and Immune System in Children With Intractable Epilepsy?
Status: UNKNOWN
Conditions: Refractory Epilepsy in Children
Interventions: DEVICE: Vagus Nerve Stimulator: Neurocybernetic prothesis NCP, Cyberonics Inc., Webster, TX, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec
Status: RECRUITING
Conditions: Healthy Volunteer|Muscular Atrophy, Spinal
Interventions: DRUG: BIIB115|DRUG: BIIB115-Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
Status: COMPLETED
Conditions: Hip Fractures|Acute Post Operative Pain|Nerve Block|Spinal Anesthesia
Interventions: OTHER: PENG Block|OTHER: SIFI compartment block|DIAGNOSTIC_TEST: Numeric Rating Scale|DIAGNOSTIC_TEST: Angle of sitting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p