pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium With or Without Zibotentan in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: zibotentan|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Endoscopic Surgery of Craniomaxillofacial (CMF) Condylar Neck Fractures
Status: COMPLETED
Conditions: Condylar Neck Fractures
Interventions: PROCEDURE: Endoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Modified Muscle Sparing Posterior Technique (SPAIRE) in Hip Hemiarthroplasty for Displaced Intracapsular Fractures.
Status: COMPLETED
Conditions: Hip Fracture
Interventions: PROCEDURE: SPAIRE|PROCEDURE: LATERAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo
Status: RECRUITING
Conditions: Emergency Contraception
Interventions: DRUG: Etonogestrel implant with Oral Levonorgestrel emergency contraception 1.5mg|DEVICE: Etonogestrel implant with oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Miniscrews as Anchorage Device for Orthodontic Treatment
Status: COMPLETED
Conditions: Orthodontic Anchorage Procedures|Orthodontic Space Closure
Interventions: DRUG: Topical anesthesia (buccal and palatal)|DRUG: Local anesthesia (buccal and palatal)|PROCEDURE: Extraction of the maxillary first premolars|DRUG: Topical anesthesia (buccal)|DRUG: Local anesthesia (buccal)|DEVICE: Molarblock|DEVICE: Spider Screw K1 short neck
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nilotinib in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: nilotinib|GENETIC: cytogenetic analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Improve HIV Antiretroviral Therapy Adherence
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: BEHAVIORAL: Financial Incentive|BEHAVIORAL: Reminders|BEHAVIORAL: Financial Incentive and Reminders|BEHAVIORAL: Information|BEHAVIORAL: Stigma-relieving|BEHAVIORAL: Information and Stigma-relieving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: OTHER: High Linoleic Acid Foods|OTHER: High Oleic Acid Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Washing Red Blood Cells on Post Heart Surgery Blood Loss
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: PROCEDURE: Residual pump blood management post aortic cannula removal|PROCEDURE: Residual pump blood management post aortic cannula removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Elective Surgery Patients
Status: COMPLETED
Conditions: Induction and Maintenance of General Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol|DRUG: Propofol HSK3486
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Soluble Fiber on Hypertriglyceridemia and Immune Profile in HIV-positive Individuals.
Status: COMPLETED
Conditions: Hypertriglyceridemia|HIV Infections
Interventions: DIETARY_SUPPLEMENT: soluble fiber® (partially hydrolyzed guar gum)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Therapeutic Effect of Intravitreal Bevacizumab and Triamcinolone in Resistant Uveitic Cystoid Macular Edema
Status: UNKNOWN
Conditions: Resistant Cystoid Macular Edema
Interventions: DRUG: Intravitreal injection of Triamcinolone|DRUG: Intravitreal injection of Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children
Status: COMPLETED
Conditions: Myopia, Progressive|Children, Only
Interventions: DEVICE: Menicon Z Night|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conduction System Pacing vs Biventricular Resynchronization Therapy in Systolic Dysfunction and Wide QRS: CONSYST-CRT.
Status: ACTIVE_NOT_RECRUITING
Conditions: Resynchronization Therapy|Conduction System Pacing
Interventions: DEVICE: Conduction system pacing|DEVICE: Biventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging Properties of PET Radiotracer [18F]3F-PHPG in Patients With Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 3-[18F]Fluoro-para-hydroxyphenethylguanidine|DRUG: [123I] metaiodobenzylguanidine|DIAGNOSTIC_TEST: Positron emission tomography/computed tomography scan|DIAGNOSTIC_TEST: Planar scintigraphy scan|DIAGNOSTIC_TEST: Single photon emission computed tomography/computed tomography scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics, Safety, Efficacy and Acceptability of Daclatasvir Plus Sofosbuvir in HCV-infected Children
Status: RECRUITING
Conditions: HCV
Interventions: DRUG: Sofosbuvir 200 MG Oral Tablet plus Daclatasvir 30 mg Oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
Status: COMPLETED
Conditions: Spinocerebellar Degeneration
Interventions: DRUG: KPS-0373, High dose|DRUG: KPS-0373, Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effects of Pilates Exercises Versus Walking on Mechanical and Vascular Variables of Individuals With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Pilates exercises|OTHER: Walking protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Mirikizumab (LY3074828) in Participants With Moderate-to-Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Mirikizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Glycemic Control Effects of Mono Therapy CKD-501 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: CKD-501 0.5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Administration of Baclofen (ITB) to Cerebral Palsy Patients With Therapy-Resistant Spasticity
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Administration of intrathecal baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Aerobic Exercise in the Rehabilitation of Patients With COVID-19-Related Myocardial Injury
Status: NOT_YET_RECRUITING
Conditions: Long COVID|Myocardial Injury
Interventions: OTHER: Assigned interventions|OTHER: conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC
Status: RECRUITING
Conditions: Non-squamous Non-small-cell Lung Cancer
Interventions: DRUG: Tiragolumab|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Participants With Moderately to Severely Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: JNJ-67864238|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of Ondansetron Oral Soluble Pellicles
Status: RECRUITING
Conditions: Nausea and Vomiting
Interventions: DRUG: Ondansetron Oral Soluble Pellicles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Norwegian Study of Persistent Atrial Fibrillation Treatment: Cryoballoon Versus Radiofrequency Catheter Ablation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation with cryoballoon catheter.|PROCEDURE: Pulmonary vein isolation with radiofrequency ablation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects Of Mud Based Plyometric Jump Training on Volleyball Players
Status: RECRUITING
Conditions: Sports Physical Therapy
Interventions: OTHER: PLYOMETRICS jump training with HIIT (4 weeks,3 sessions per week)|OTHER: PLYOMETRICS JUMP TRAINING WITHOUT HIIT (4weeks, 3sessions Per week)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Time-Lapse Incubation for Embryo Culture - Morphokinetics and Environmental Stability
Status: UNKNOWN
Conditions: Infertility|Genetic Diseases
Interventions: DEVICE: Miri, Benchtop Multi-room incubator|DEVICE: Miri TL, Time-Lapse incubator|DEVICE: Miri TL, Time-Lapse incubator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inguinal Hernia Repair on Uroflowmetric Parameteres
Status: COMPLETED
Conditions: Inguinal Hernia|Urinary Retention|Lower Urinary Tract Symptoms
Interventions: PROCEDURE: Inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Poplar-type Propolis Dry Extract ESIT12 : Nutrikinetic and Bioavailability Studies
Status: COMPLETED
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: ESIT12 D|DIETARY_SUPPLEMENT: ESIT12 4D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myeloprotection With Trilaciclib in Pan-cancer Population
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer|Breast Cancer|Endometrial Cancer|Cervical Cancer|Head And Neck Squamous Cell Carcinomas
Interventions: DRUG: Trilaciclib Injection|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Algae and Cholesterol Absorption
Status: COMPLETED
Conditions: Intestinal Cholesterol Absorption
Interventions: DIETARY_SUPPLEMENT: Wakame|DIETARY_SUPPLEMENT: Spirulina|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Method to Determine the Size of Laryngeal Mask Airway (LMA)
Status: COMPLETED
Conditions: Ear Based ProSeal LMA
Interventions: DEVICE: Ear-sized based
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda
Status: WITHDRAWN
Conditions: Intermittent Preventive Treatment|Placental Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TCHCCT-Zhong-Xing-Emergency-Department-airway
Status: UNKNOWN
Conditions: Airway Complication of Anesthesia|Intubation;Difficult
Interventions: PROCEDURE: holding position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Grazoprevir|DRUG: Boceprevir|DRUG: Placebo for Grazoprevir|DRUG: Placebo for Boceprevir|DRUG: Peg-interferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesoglycan (Prisma®) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Superficial Venous Thrombosis of Leg, Secondary Prevention
Interventions: DRUG: Mesoglycan Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treat of Functional Ovarian Cysts by Compare Between Cocs and Progesterone Only Pills
Status: UNKNOWN
Conditions: Ovarian Neoplasms
Interventions: DRUG: Combined Oral Contraceptive|DRUG: Progestin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deposit Contracts to Increase Accessibility of a Contingency Management Intervention to Reduce Problematic Drinking
Status: RECRUITING
Conditions: Alcohol Abuse|Alcohol Intervention|Transdermal Alcohol Monitoring|Contingency Management|Deposit Contract
Interventions: BEHAVIORAL: Deposit Contract|OTHER: Transdermal Alcohol Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide
Status: COMPLETED
Conditions: Glioblastoma|Glioma
Interventions: PROCEDURE: Functional MRI imaging and tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response
Status: COMPLETED
Conditions: Leukemia, Chronic Myeloid
Interventions: DRUG: imatinib|DRUG: nilotinib|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AURELIA: A Study of Avastin (Bevacizumab) Added to Chemotherapy in Patients With Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: liposomal doxorubicin|DRUG: paclitaxel|DRUG: topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dissemination and Implementation of Improving Pediatric Obesity Practice Using Prompts
Status: RECRUITING
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Improving Pediatric Obesity Practice Using Prompts (iPOP-UP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs
Status: COMPLETED
Conditions: Urinary Tract Infections, Recurrent
Interventions: DRUG: Trimethoprim|DRUG: Methenamine hippurate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of IV Doses of GMI-1070 on Qtc Intervals in Healthy African-American Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivipansel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Topical NanoDox® for Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Nanodox 1% (doxycycline monohydrate hydrogel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PREVENTION Trial: Precision Recommendations to Optimize Neurocognition
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Data-Driven Clinical Recommendations|BEHAVIORAL: Coached Data-Driven Clinical Recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VaLidation of the Simple Adaptation of the Kardia 6L ECG Recorder to Obtain Chest leAd equivaLents: a Multi-centre International (LOCAL-ECG) Study; on Behalf of the Africa Heart Rhythm Association Investigators
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DEVICE: Kardia 6L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sprinter Legend Balloon Catheter
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention|DEVICE: Sprinter Legend 1.25mm Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: ECMO|High-risk PCI
Interventions: PROCEDURE: Standby cannulated ECMO|PROCEDURE: Prophylactic ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis, Coronary
Interventions: DRUG: Autologous CD34+ Cells|DRUG: Granulocyte Colony-Stimulating Factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIB TL + YCWP + DC in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: TLPLDC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Losartan Potassium and Hydrochlorothiazide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Assessing Body Posture and Postural Balance Among Young Adults With Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: OTHER: 3D/4D spine and posture analysis "DIERS FORMETRIC 4D" ,The Biodex Balance System SD-
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutrition and Exercise Prehabilitation to Reduce Morbidity Following Major Liver Surgery in Sarcopenic Patients
Status: RECRUITING
Conditions: Liver Cancer|Surgery|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Nutrition|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Baby-CIMT in Infants Younger Than 12 Months
Status: COMPLETED
Conditions: Cerebral Palsy|Hemiplegia|Children
Interventions: BEHAVIORAL: Baby-CIMT|BEHAVIORAL: Baby-Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Hypofractionation|Radiotherapy|Proton Therapy|Immune System Suppression
Interventions: RADIATION: HYpofractionated, Dose-redistributed RAdiotherapy (HYDRA)|RADIATION: conventional fractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Photoirritation Potential of PEP005 (Ingenol Mebutate) Gel, 0.01% in Healthy Volunteers
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: PEP005 (ingenol mebutate) Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chlorhexidine Gel on Bacterial Count During Fixed Orthodontic Treatment
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication|Dental Caries
Interventions: DRUG: Chlorhexidine gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Can Doctors Reduce COVID-19 Misinformation and Increase Vaccine Uptake in Ghana? A Cluster-randomised Controlled Trial
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Motivational Interviewing, AIMS|BEHAVIORAL: Facility engagement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Spatial Neglect and Delirium After Stroke
Status: COMPLETED
Conditions: Stroke|Delirium|Spatial Neglect
Interventions: DIAGNOSTIC_TEST: Confusion Assessment Method|DIAGNOSTIC_TEST: Behavioral Inattention Test|DIAGNOSTIC_TEST: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Florida Mental Status Examination|DIAGNOSTIC_TEST: Montreal Cognitive Assessment|DIAGNOSTIC_TEST: Geriatric Depression Scale|DIAGNOSTIC_TEST: Kessler Foundation Neglect Assessment Process
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors
Status: UNKNOWN
Conditions: Brain Tumor
Interventions: PROCEDURE: high-dose chemotherapy and autologous stem cell rescue|PROCEDURE: high-dose chemotherapy and autologous stem cell rescue|PROCEDURE: high-dose chemotherapy and autologous stem cell rescue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Intake of Animal and Plant Proteins on the Metabolism in Healthy Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Isolated Pea Protein|DIETARY_SUPPLEMENT: Isolated Whey Protein|DIETARY_SUPPLEMENT: Isolated Faba Bean Protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augmentation
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: SKY0402|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: MBG453|DRUG: NIS793|DRUG: canakinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardized Lycium Chinense Fruit Extract Enhances Attention and Cognitive Function in Healthy Young People
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Standardized Lycium chinense Fruit Extract (LCF) capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fatigue and Skeletal Muscle Impact in Severe Axial Spondyloarthritis
Status: NOT_YET_RECRUITING
Conditions: Spondyloarthritis, Axial|Fatigue|Exercise Capacity
Interventions: OTHER: Measurement of aerobic exercise on cycloergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Randomized Controlled Trial|Subjective Cognitive Impairment
Interventions: OTHER: Cognitive stimulation|OTHER: Stimulating leisure activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validating Clinical Efficacy for Integrated Psychological Intervention for Obesity: Physical Therapy and Psychotherapy
Status: COMPLETED
Conditions: Mental Health Issue|Body Image
Interventions: PROCEDURE: Liposuction|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Protocol for Subjects Who Were Previously Enrolled in Other Tivantinib (ARQ 197) Protocols
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Tivantinib|DRUG: Anti-Cancer Combination Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure
Status: COMPLETED
Conditions: Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSC)|BIOLOGICAL: c-kit+ cells|BIOLOGICAL: Placebo (Plasmalyte A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Formulations of the L-PPDS in Subjects With OH or OAG
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Formulation E1 of L-PPDS|DRUG: Formulation E2 of L-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin in Treating Patients With Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction
Status: COMPLETED
Conditions: Colorectal Cancer|Constipation, Impaction, and Bowel Obstruction|Gastric Cancer|Gastrointestinal Carcinoid Tumor|Gastrointestinal Stromal Tumor|Quality of Life|Small Intestine Cancer
Interventions: PROCEDURE: bowel obstruction management|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of TLR4 on Lipid-induced Insulin Resistance
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DRUG: Eritoran|DRUG: D5W (5% Dextrose in water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TR-701 FA vs Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin and Subcutaneous Tissue Bacterial Infections
Interventions: DRUG: TR-701 FA|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Transcranial Direct Current Stimulation With Intermittent Oral to Esophageal Tube for Stroke-related Dysphagia
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Comprehensive rehabilitation therapy|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Transcranial direct current stimulation|BEHAVIORAL: Placebo Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: SPM 927
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second Look Laparoscopy in Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: peritonectomy|DRUG: Folinic Acid|DRUG: 5-Fluorouracil|DRUG: Oxaliplatin|DRUG: systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Screening Tool in Geriatric Oncology
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Head and Neck Cancer|Lung Cancer|Lymphoma|Prostate Cancer
Interventions: OTHER: Geriatric screening tests|OTHER: Multidimensional geriatric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Music Therapy on Pain Level and Analgesic Consumption
Status: COMPLETED
Conditions: Orthopedic Surgery|Pain, Postoperative|Analgesia
Interventions: DEVICE: Music Therapy Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy|Postoperative Analgesia|Erector Spinae Plane Block|Quadratus Lumborum Block
Interventions: OTHER: Control group|PROCEDURE: Erector spinae plane block group|PROCEDURE: Quadratus lumborum block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Maxigesic® on Intraoperative Remifentanil Requirement
Status: NOT_YET_RECRUITING
Conditions: Opioid Use
Interventions: DRUG: Maxigesic administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Retrospective and Prospective Study on Professional Continuous Glucose Monitoring in Insulin-treated Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Continuous Glucose Monitoring (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neonatal Resuscitation With Intact Cord
Status: COMPLETED
Conditions: Intraventricular Hemorrhage
Interventions: PROCEDURE: V-DCC|PROCEDURE: Delayed cord clamping|PROCEDURE: Dry and and if apneic initially can stimulate by gently rubbing the back for approximately 30 seconds with warm sterile towels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Knowledge, Attitudes, and Practice of Surgeons Toward Nutrition Support in HIPEC Patients
Status: COMPLETED
Conditions: Pseudomyxoma Peritonei|Appendiceal Neoplasms|Pancreatic Neoplasms|Neoplasm Metastasis|Adenocarcinoma|Sarcoma|Uterine Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily REmote Ischaemic Conditioning Following Acute Myocardial Infarction
Status: COMPLETED
Conditions: Post Myocardial Infarction
Interventions: PROCEDURE: Remote Ischaemic Conditioning administered via the inflation of a blood pressure cuff on the upper arm|PROCEDURE: Sham conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Naloxone for Optimizing Hypoxemia Of Lung Donors
Status: COMPLETED
Conditions: Brain Death|Organ Donors|Lung Transplantation
Interventions: DRUG: Naloxone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy.
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: FCFD4514S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adult Traumatic Rib Fractures With Percutaneous Cryoneurolysis
Status: RECRUITING
Conditions: Rib Fractures
Interventions: DEVICE: Cryoneurolysis of Intercostal Nerves|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCA
Status: WITHDRAWN
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: Fenofibrate|DRUG: UDCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequelae of COVID-19 With Focus on Exercise Capacity and Underlying Mechanisms
Status: RECRUITING
Conditions: Patients Post-COVID-19|Controls
Interventions: DIAGNOSTIC_TEST: Cardiorespiratory fitness|DIAGNOSTIC_TEST: Lung function|DIAGNOSTIC_TEST: Muscular strength and balance tests|DIAGNOSTIC_TEST: Micro- and macrovascular endothelial function and cardiac function|DIAGNOSTIC_TEST: Blood sampling and analysis|DIAGNOSTIC_TEST: Physical activity|DIAGNOSTIC_TEST: Questionnaires|DIAGNOSTIC_TEST: Body composition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Establish Safety & Efficacy of a Combination of Dexamethasone and Lenalidomide in Patients With Relapsed or Refractory Chronic Lymphocytic Leukaemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide & Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.
Status: COMPLETED
Conditions: Antioxidants|Oxidative Stress|Inflammation|Lipid Peroxidation
Interventions: DIETARY_SUPPLEMENT: melatonin supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lag of Accommodation With DOT Spectacle Lenses
Status: COMPLETED
Conditions: Myopia, Myopia Progression, Lag of Accommodation, Hyperopic Retinal Blur, Reduction in Contrast
Interventions: DEVICE: DOT Pattern|DEVICE: Control Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Interleukin-6 and Procalcitonin as Novel Inflammatory Biomarkers in Evaluating COVID 19 Disease Severity - an Experience at CMH Quetta
Status: COMPLETED
Conditions: Covid19 Positive Patients
Interventions: DIAGNOSTIC_TEST: Interlukein 6 and procalcitonin serum levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention Study to Prevent Obesity in Sedentary 8 Year Old Swedish Children
Status: WITHDRAWN
Conditions: Cardiovascular Risk Factors|Metabolic Risk Factors|Sedentary Lifestyle|Overweight
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Physical activity|DIETARY_SUPPLEMENT: Supplementation with fish liver oli capsules|DIETARY_SUPPLEMENT: Placebo oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators
Status: COMPLETED
Conditions: Psilocybin|Hallucinogens|Pharmacologic Actions|Central Nervous System Agents|Therapeutic Uses|Psychotropic Drugs
Interventions: DRUG: psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paclitaxel and TAK-228 in Urothelial Carcinoma
Status: UNKNOWN
Conditions: Metastatic Urothelial Cancer
Interventions: COMBINATION_PRODUCT: Paclitaxel and TAK-228
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mass Drug Administration of Azithromycin on Mortality and Other Outcomes Among 1-11 Month Old Infants in Mali
Status: RECRUITING
Conditions: Mortality
Interventions: DRUG: Placebo|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botox and Suction-Curettage for Treatment of Excessive Underarm Sweating (Axillary Hyperhidrosis)
Status: COMPLETED
Conditions: Axillary Hyperhidrosis
Interventions: DRUG: Botulinum Toxin Type A|DEVICE: Suction-Curettage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NOVOsyn® for Trocar Incision After Laparoscopic Appendectomy and Cholecystectomy
Status: COMPLETED
Conditions: Appendicitis|Cholecystitis
Interventions: DEVICE: Novosyn® CHD for fascia and skin closure|DEVICE: Novosyn® for fascia and skin closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: NBI-1117568|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate the Safety, Tolerance, Pharmacokinetics/Pharmacodynamics and Efficacy of SYHA1402 Tablets For the Treatment of Patients With Diabetic Peripheral Neuropathy in China
Status: UNKNOWN
Conditions: Distal Symmetric Polyneuropathy (DSPN)
Interventions: DRUG: SYHA1402 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)
Status: COMPLETED
Conditions: Neurofibromatoses
Interventions: DRUG: Part 1 Levulan injection|DRUG: Part 1 Levulan surface application|DRUG: Part 1 Levulan surface application twice|DRUG: Part 1 Levulan surface application twice with microneedling|DRUG: Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 1|DRUG: Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 2|DRUG: Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo
Status: ENROLLING_BY_INVITATION
Conditions: Vitiligo
Interventions: DRUG: Upadacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Eating for Eating Behavior Individuals Overweight and Obesity
Status: COMPLETED
Conditions: Overweight and Obesity|Behavior, Eating|Feeding Patterns
Interventions: BEHAVIORAL: Mindful Eating|OTHER: Standard dietary treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thrombosomes® in Bleeding Thrombocytopenic Patients Study
Status: TERMINATED
Conditions: Thrombocytopenia|Hematologic Malignancy|Bone Marrow Aplasia|Myeloproliferative Disorders|Myelodysplastic Syndromes|Platelet Refractoriness
Interventions: BIOLOGICAL: Thrombosomes|BIOLOGICAL: Liquid Stored Platelets (LSP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Educational Intervention in Patients With Low-Risk Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Educational brochures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic
Status: WITHDRAWN
Conditions: Pain|Total Knee Arthroplasty
Interventions: DRUG: Dexamethasone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safty and Immunogenicity Study of SCT1000 in Healthy Women Aged 18 to 45 Years
Status: UNKNOWN
Conditions: HPV Infection Vaccine Safety SCT1000
Interventions: DRUG: SCT1000|DRUG: Gardasil®9|DRUG: placebo|DRUG: Gardasil®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Reflexology Versus Acupressure on Sleep Disturbance and Hot Flashes
Status: RECRUITING
Conditions: Postmenopausal Flushing|Hot Flashes
Interventions: OTHER: Foot Reflexology|OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SCY-635, Pegasys and Copegus in Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: Placebo|DRUG: SCY-635|DRUG: Pegasys|DRUG: Copegus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Education Program for Patients Receiving Oral Anticoagulation
Status: UNKNOWN
Conditions: Cardiovascular Disease|Venous Thromboses|Atrial Fibrillation|Blood Coagulation Disorders, Inherited
Interventions: BEHAVIORAL: Educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE