pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer|Squamous Cell Carcinoma|Adenocarcinoma of the Lung
Interventions: DRUG: AXL1717|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics in Reducing Infections and Allergies in Young Children During the Complementary Feeding Period
Status: TERMINATED
Conditions: Days Absent From Day Care|Respiratory Tract Infections|Gastrointestinal Infections|Allergy
Interventions: DIETARY_SUPPLEMENT: Probiotic (10^9 CFU/day)|DIETARY_SUPPLEMENT: Probiotic (10^8 CFU/day)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Low Dose Dexmedetomidine in Sedation Colonoscopy
Status: NOT_YET_RECRUITING
Conditions: Colonoscopy
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: DRUG: Triclosan, Fluoride|DRUG: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome
Status: UNKNOWN
Conditions: Dry Eye Syndromes
Interventions: BEHAVIORAL: Clinical Decision Support System|OTHER: Routine intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chyme Reinfusion for Type 2 Intestinal Failure
Status: RECRUITING
Conditions: Intestinal Failure|Enterocutaneous Fistula|Ileostomy - Stoma
Interventions: DEVICE: The Insides System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Fomivirsen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals
Status: COMPLETED
Conditions: Opioid Abuse|Opioid Dependence
Interventions: DRUG: buprenorphine|DRUG: morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Slimming gel|OTHER: Slimming gel placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Online Intervention for Traumatic Brain Injury Wellbeing
Status: RECRUITING
Conditions: Traumatic Brain Injury|Attention Impaired|Emotional Regulation
Interventions: BEHAVIORAL: Online group 1|BEHAVIORAL: Online group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Kidney Damage Associated With Tobacco Use
Status: COMPLETED
Conditions: Kidney Injury|Kidney Disease, Chronic|Tobacco Toxicity
Interventions: DIAGNOSTIC_TEST: Early kidney damage biomarkers|DIAGNOSTIC_TEST: Predisposition to kidney injury biomarkers|DIAGNOSTIC_TEST: Tobacco consumption
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Preventive Effects of Sub Hypnotic Dose of Propofol for Nausea and Vomiting Induced by Hemabate
Status: COMPLETED
Conditions: Nausea and Vomiting
Interventions: DRUG: Propofol|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Center Study on Comparing the Different Function of EndoAngel in Improving the Quality of Colonscopy
Status: UNKNOWN
Conditions: Adenoma
Interventions: DIAGNOSTIC_TEST: Colonoscopy with the assistance of EndoAngel's polyp detection function.|DIAGNOSTIC_TEST: Colonoscopy with the assistance of EndoAngel's quality monitoring function.|DIAGNOSTIC_TEST: Colonoscopy without the assistance of EndoAngel's any function.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Molecular Mechanism Identification in Inherited Arrhythmias and Valvulopathies From Induced Pluripotent Stem Cells
Status: TERMINATED
Conditions: Inherited Arrhythmias and Valvulopathies
Interventions: OTHER: Skin biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: A Study Using Recombinant Human Chorionic Gonadotrophin (rhCG, Ovidrel®) in the Induction of Final Follicle Maturation and Early Luteinization in Chinese Women Undergoing in Vitro Fertilization and Embryo Transfer (IVF/ET)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: r-hCG|DRUG: Urinary-hCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freiburg TIPS Registry
Status: RECRUITING
Conditions: Liver Cirrhosis|Portal Hypertension|Non-Cirrhotic Portal Hypertension|Budd Chiari Syndrome|Portal Vein Thrombosis|Portal Systemic Shunt
Interventions: DEVICE: Implantation of a transjugular intrahepatic portosystemic shunt (TIPS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness Study of Dragonfly System for Degenerative Mitral Regurgitation
Status: ENROLLING_BY_INVITATION
Conditions: Degenerative Mitral Valve Disease
Interventions: DEVICE: Dragonfly Transcatheter Mitral Valve Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intraoperative Stimulation of Acupoints on Postoperative Gastrointestinal Motility Recovery
Status: UNKNOWN
Conditions: Gastrointestinal Dysfunction
Interventions: DEVICE: acupuncture treatment|DEVICE: sham acupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: US-guided Trocar Versus Seldiger Technique for Percutaneous Cholecystostomy
Status: COMPLETED
Conditions: Cholecystitis
Interventions: PROCEDURE: Trocar percutaneous cholecystostomy|PROCEDURE: Seldinger percutaneous cholecystostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)
Status: UNKNOWN
Conditions: Uremic Pruritus
Interventions: DRUG: Nalfurafine HCl 2.5 µg|DRUG: Nalfurafine HCl 5.0 µg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women
Status: COMPLETED
Conditions: Transgender Health|Gender Dysphoria|Transgender Women|Human Immunodeficiency Virus
Interventions: DRUG: Doravirine/Lamivudine/Tenofovir|DRUG: Spironolactone 100mg|DRUG: Estradiol 2mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Korean Red Ginseng on Women With Cold Hypersensitivity of Hands and Feet
Status: COMPLETED
Conditions: Cold Hypersensitivity
Interventions: DRUG: Korean red ginseng|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency?
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: 4-PBA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension
Status: RECRUITING
Conditions: Uncontrolled Hypertension
Interventions: DRUG: Baxdrostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of an Online Intervention for the Treatment of Diabetes Distress in Patients With Type 1-Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Diabetes Distress
Interventions: BEHAVIORAL: Online psychological intervention|BEHAVIORAL: Individual psychological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHOspholamban RElated CArdiomyopathy STudy - Intervention
Status: COMPLETED
Conditions: Phospholamban R14del Mutation-related Cardiomyopathy
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoral Versus Extraoral Manual Therapy in Subjects With Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Disorder
Interventions: OTHER: Intraoral manual therapy|OTHER: Extraoral manual therapy|OTHER: Exercise and counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SGLT-2 Inhibition, Metabolomics and Cardiovascular/Kidney Disease
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 10 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Facial Emotion Recognition in Patients With Euthymic Bipolar Disorder I and II
Status: COMPLETED
Conditions: Social Cognition|Facial Emotion Recognition|Facial Affect|Bipolar Disorder I and II
Interventions: OTHER: Facial emotion recognition test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Research on the Safety and Efficacy of Blocking Dural Blood Supply in Glioblastoma Patients
Status: RECRUITING
Conditions: Glioblastoma|Meningeal Arteries
Interventions: PROCEDURE: interventional procedure to block bilateral meningeal blood supply
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Available Fluoride Toothpaste in Reducing Plaque and Gingivitis
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis
Interventions: DRUG: MFP Fluoride toothpaste|DRUG: Stannous fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implant Placement and Simultaneous Soft Tissue Grafting With Single or Double Layers of Acellular Dermal Matrix
Status: COMPLETED
Conditions: Clinical Efficacy
Interventions: PROCEDURE: One layer allograft|PROCEDURE: Two layer allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Walking, Difficulty|Spastic Diplegia|Hemiplegic Cerebral Palsy
Interventions: OTHER: MOBILE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abnormal Coronary Vasomotion in Patients With Suspected Coronary Artery Disease (CAD)
Status: RECRUITING
Conditions: Coronary Vasospasm|Microvascular Angina|Coronary Artery Disease
Interventions: OTHER: Intracoronary acetylcholine provocation test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Dose Prolonged Infusion of Tissue Type Plasminogen Activator Therapy in Massive Pulmonary Embolism
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: DRUG: 25 mg Actilyse ( Boehringer Ingelheim, Germany) infusion in 6 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Decontamination in Treatment of Peri-Implantitis
Status: WITHDRAWN
Conditions: Peri-implantitis
Interventions: PROCEDURE: Gauze|PROCEDURE: Titanium brush|PROCEDURE: Air powder abrasion|PROCEDURE: Comprehensive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of F373280
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: 1g of F373280|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Response to an Intervention Using Guided, At-Home Technology for the Mind
Status: RECRUITING
Conditions: Cognition|Brain Health|Brain Structure|Brain Function
Interventions: DEVICE: Digital Program 1|DEVICE: Digital Program 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine, Epirubicin, and Carboplatin in Treating Patients With Progressive, Unresectable, or Metastatic Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Liver Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: capecitabine|DRUG: carboplatin|DRUG: epirubicin hydrochloride|GENETIC: microarray analysis|GENETIC: polymorphism analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection
Status: COMPLETED
Conditions: Hepatitis c
Interventions: DRUG: Two tablets of EHCV in Single Dose each tablet containing SOF 200 mg, RBV 500 mg and Natural anti-hemolytic (AH) at 200 mg|DRUG: Sofosbuvir tablet (SOF) 400 mg - once daily|DRUG: Ribavirin (RBV) 1000 mg - splitted on 2 doses daily - 600 mg on morning and 400 mg on evening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prednisone and Aspirin on IVF-ET Outcome Among Patients With Thyroid Autoimmunity
Status: NOT_YET_RECRUITING
Conditions: Thyroiditis, Autoimmune|Infertility
Interventions: DRUG: Prednisone and Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CAR-BCMA T in Patients With Refractory or Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Refractory or Relapsed Multiple Myeloma
Interventions: GENETIC: CAR-BCMA T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial to Assess the Performance and Tolerance of mRDX-02-17 Dermal Filler in the Facial Rejuvenation
Status: COMPLETED
Conditions: Facial Rejuvenation
Interventions: DEVICE: mRDX-02-17
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ready to Use Therapeutic Food (RUTF) to Promote Growth in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Cystic Fibrosis Ready to Use Supplemental Food
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NightWare Open Enrollment Study
Status: UNKNOWN
Conditions: PostTraumatic Stress Disorder|Sleep Disorder|Stress Disorder|Sleep Initiation and Maintenance Disorders|Combat Disorders|Nightmares Associated With Chronic Post-Traumatic Stress Disorder|Nightmare|Nightmares, REM-Sleep Type
Interventions: DEVICE: NightWare Therapeutic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Traditional Chinese Treatment Combined Adjuvant Chemotherapy in IIIb and IIIc Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer Stage IIIB|Gastric Cancer Stage IIIC
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|OTHER: TCM|DRUG: S-1|DRUG: Docetaxel|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab as First Line Therapy in Patients With Unresectable Squamous Cell Carcinoma of the Skin
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle Guiding Robot for Radiofrequency Ablation: Safety and Efficacy Study on Hepatocellular Carcinoma Patients
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: Needle guiding robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lot-to-Lot Consistency of V114 in Healthy Adults (V114-020)
Status: COMPLETED
Conditions: Pneumococcal Infections|Pneumonia, Pneumococcal
Interventions: DRUG: V114|DRUG: Prevnar 13™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treating Acute Pancreatitis With Dabigatran, a Pilot Study
Status: TERMINATED
Conditions: Acute Pancreatitis
Interventions: DRUG: Dabigatran Etexilate Mesylate|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Two Different Formulation of Voriconazole
Status: COMPLETED
Conditions: Fungus Infection
Interventions: DRUG: Vaway FC Tablets 200mg (Voriconazole)|DRUG: VFEND FC Tablets 200mg (Voriconazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Transfer for Sickle Cell Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: single infusion of autologous bone marrow derived CD34+ HSC cells transduced with the lentiviral vector containing a short-hairpin RNA targeting BCL11a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lavage of the Uterine Cavity for the Diagnosis of Ovarian and Tubal Carcinoma - Study of Sensitivity and Specificity
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer
Interventions: PROCEDURE: Lavage of the Cavum uteri and proximal fallopian tubes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Aleurone-enriched Products on Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Glucose and Lipid Metabolism|Incretin Hormones Plasma Levels|Inflammation, Oxidative Stress and Endothelial Function
Interventions: OTHER: Aleurone|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Probiotics on Aging Population
Status: UNKNOWN
Conditions: Debility
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum|DIETARY_SUPPLEMENT: A placebo made of starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|BIOLOGICAL: PfSPZ Challenge Material|DRUG: PBS and HSA Diluent|OTHER: Normal Saline|DRUG: Coartem|DRUG: ASAQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AZD8529 Single Ascending Dose Study in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD8529|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors
Status: RECRUITING
Conditions: Osteosarcoma|Sarcoma|Sarcoma,Soft Tissue|Bone Tumor
Interventions: DRUG: Recombinant oncolytic herpes simplex virus type Ⅰ (R130)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Azithromycin to Treat Cutaneous Leishmaniasis
Status: TERMINATED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Glucantime®|DRUG: Zithromax ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by Surgery
Status: COMPLETED
Conditions: Adult Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temsirolimus|DRUG: Tivantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Safety Study of ALKS 9072 (Also Known as ALKS 9070)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ALKS 9072, Low|DRUG: ALKS 9072, High
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With ATRA-IV and Depakote in Patients With Advanced Solid Tumor Malignancies
Status: TERMINATED
Conditions: Solid Tumor Malignancies
Interventions: DRUG: ATRA-IV|DRUG: Depakote
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: [18F] Fluciclovine PET/MRI|DRUG: [18F] fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)
Status: NOT_YET_RECRUITING
Conditions: Dyspnea|Chronic Obstructive Pulmonary Disease|Asthma
Interventions: DEVICE: Lung Master (Pulmonary Exerciser)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavir
Status: UNKNOWN
Conditions: Portal Hypertension
Interventions: DRUG: Entecavir|DRUG: Entecavir + Fuzheng Huayu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occupational Therapy in the Rehabilitation of Executive Functions in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Refractory Schizophrenia
Interventions: OTHER: Craft Activities|BEHAVIORAL: OGI Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Between Silicone Ahmed Glaucoma Valves and Second Trabeculectomy in Glaucoma Patients
Status: UNKNOWN
Conditions: Open Angle Glaucoma
Interventions: PROCEDURE: second Trabeculectomy|PROCEDURE: Ahmed Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Intrusive Memories in Refugees and Asylum Seekers With PTSD
Status: TERMINATED
Conditions: Post Traumatic Stress Disorder|Stress Disorders, Post-Traumatic|Stress Disorders, Traumatic|Trauma, Psychological|Trauma and Stressor Related Disorders|Mental Disorder
Interventions: BEHAVIORAL: Brief cognitive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 2.5 mg saxagliptin / 5 mg dapagliflozin / 850 mg metformin XR FDC tablet|DRUG: 2.5 mg saxagliptin / 5 mg dapagliflozin / 1000 mg metformin XR FDC tablet|DRUG: 5 mg dapagliflozin / 850 mg metformin XR FDC|DRUG: 5 mg dapagliflozin / 1000 mg metformin XR FDC|DRUG: 2.5 mg ONGLYZA® (saxagliptin) tablet|DRUG: 5 mg Forxiga® (dapagliflozin) tablet|DRUG: 500 mg Glucophage XR®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilumab in CRSsNP
Status: COMPLETED
Conditions: Chronic Rhinosinusitis Without Nasal Polyps|Sinusitis|Chronic Sinusitis|Sinus Disorder|Respiratory Disorder
Interventions: DRUG: Dupilumab SAR231893|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Axatilimab in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Axatilimab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Pegylated Interferon Alfa-2a in Treating Patients With Recurrent or Progressive Brain Metastases Due to Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: PEG-interferon alfa-2a|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambu AuraGain and Teleflex LMA Protector Fiberoptic Assessments in Elective Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Ambu AuraGain|DEVICE: Teleflex LMA Protector|DEVICE: Ambu aScope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Performance of Implantable Cardiac Monitors and Cardiac Implantable Electronic Devices in Detecting Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Confirm Rx (Implantable Cardiac Monitor)|DEVICE: Reveal LINQ (Implantable Cardiac Monitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Effects of Non-invasive Ventilation in Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: RADIATION: Functional Respiratory Imaging|OTHER: Lung compliance measurement|DEVICE: Non-invasive ventilation (Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adult Study Oxytocin - fMRI
Status: COMPLETED
Conditions: Schizophrenia|Oxytocin|Social Cognition|Functional Magnetic Resonance Imaging (fMRI)
Interventions: DRUG: Oxytocin|DRUG: Saline Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study
Status: COMPLETED
Conditions: Alcohol Use Disorder (AUD)|Post Traumatic Stress Disorder (PTSD)
Interventions: DRUG: Placebo|DRUG: Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg|DRUG: Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg|PROCEDURE: Ethanol Infusion|BEHAVIORAL: PTSD Reactivity Condition|BEHAVIORAL: Alcohol Cue Reactivity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Deficit Fields for Stroke Recovery
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Deficit-fields to reduce error|BEHAVIORAL: Deficit-fields to expand range of motion|BEHAVIORAL: Deficit-fields to improve function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Dissection Before Or After Cystectomy
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: OTHER: Lymph node dissection before bladder resection|OTHER: Lymph node dissection after bladder resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Add-on Citalopram to Risperidone on Negative Symptoms in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Negative Symptoms
Interventions: DRUG: Risperidone|DRUG: risperidone|DRUG: Citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction.
Status: COMPLETED
Conditions: Heart Failure (HF)
Interventions: DRUG: Ivabradine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Succinylated Gelatin on the Blood Viscosity and Oxygen Delivery
Status: UNKNOWN
Conditions: Blood Viscosity
Interventions: DRUG: Ringer's lactate solution|DRUG: Succinylated gelatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Sleep Focused Parenting Intervention for Preschool Aged Children at Risk for ADHD
Status: RECRUITING
Conditions: Attention Deficit and Disruptive Behavior Disorders|Attention Deficit Hyperactivity Disorder|Child, Preschool|Sleep|Sleep Disturbance
Interventions: BEHAVIORAL: Brief Parent Behavioral Intervention|BEHAVIORAL: Sleep-Focused Parent Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study)
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare the Efficacy and Safety Of MW05 and PEG-rhG-CSF
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: MW05|DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOod Additives on the Mucosal Barrier
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Dietary Emulsifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Nutrition Education Given by Pecha Kucha Method on Preventing Malnutrition to Cancer Patients Receiving Radiotherapy
Status: RECRUITING
Conditions: Preventing Malnutrition
Interventions: BEHAVIORAL: pecha kucha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study Of Etrolizumab Followed By Open-Label Extension And Safety Monitoring In Pediatric Patients With Moderate To Severe Ulcerative Colitis Or Moderate To Severe Crohn's Disease
Status: TERMINATED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Etrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation in Blunt Cerebrovascular Injuries
Status: WITHDRAWN
Conditions: Carotid Artery Injury|Vertebral Artery Injury
Interventions: DRUG: heparin|DRUG: aspirin and clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia
Status: COMPLETED
Conditions: Intubation Complication
Interventions: DRUG: Intravenous morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Montelukast Post-Marketing Comparative Study With Ketotifen (0476-379)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0476, montelukast sodium / Duration of Treatment: 4 Weeks|DRUG: Comparator: ketotifen / Duration of Treatment: 4 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: BEET PAH: a Study to Assess the Effects of Beetroot Juice in Patients With Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DIETARY_SUPPLEMENT: Beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy
Status: COMPLETED
Conditions: Neuralgia|Neuropathic Pain|Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Magnetic Peripheral Nerve Stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liposomal Doxorubicin and Estramustine Phosphate: Study in Taxane Resistant, Hormone Refractory Advanced Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Doxil and Estramustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Examining Plasma Exchange Using the Becton Dickinson (BD) Catheter In an Outpatient Apheresis Unit
Status: COMPLETED
Conditions: Plasma Exchange
Interventions: DEVICE: 20-gauge BD Nexiva Diffusics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Individualized Instruction Versus Pamphlet in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: PROCEDURE: Tailored educational program|PROCEDURE: Educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: ECT
Clinical trial: Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Memantine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Elafibranor on Hepatic Lipid Composition in Subjects With Nonalcoholic Fatty Liver (NAFL)
Status: TERMINATED
Conditions: Non-Alcoholic Fatty Liver
Interventions: DRUG: elafibranor 120mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Peer-Oriented HIV Prevention Outreach Program for Individuals at High Risk for HIV and Other STIs
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Peer-oriented intervention|BEHAVIORAL: Group cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
Status: COMPLETED
Conditions: Hypertension|Congestive Cardiomyopathy
Interventions: DRUG: Enalaprilat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
Status: RECRUITING
Conditions: Familial Dysautonomia
Interventions: DRUG: Dexmedetomidine Sublingual
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Status: UNKNOWN
Conditions: Lumbar Herniated Disc
Interventions: PROCEDURE: Microdiscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Study of TACE Plus Oral Sorafenib for Unresectable HCC
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib|DRUG: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Cryopreserved Osteochondral Allograft Cores for the Treatment of Osteochondral Lesions in the Knee
Status: NOT_YET_RECRUITING
Conditions: Osteochondral Defect
Interventions: PROCEDURE: osteochondral transplant on the femoral condyle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD)
Status: COMPLETED
Conditions: Diabetes|Hypertension|Diabetic Kidney Disease
Interventions: BEHAVIORAL: Pharmacist telehealth intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Risk of Osteoarthritis of the Knee at Least 5 Years After ACL Reconstruction: Comparative Study Between an Isolated ACL Reconstruction and a Reconstruction Combining ACL and ALL
Status: UNKNOWN
Conditions: ACL|Anterior Curciate Ligament|Anterolateral Ligament|Knee Injuries|ALL
Interventions: PROCEDURE: Radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Intraoperative Methadone for Postoperative Pain in Patients Undergoing Tonsillectomy
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Methadone|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Pharmacokinetics of LFF269 in Healthy Volunteers and Patients With Hypertension
Status: TERMINATED
Conditions: Part 1 - Healthy Volunteers|Part 2 - Patients With Hypertension
Interventions: DRUG: LFF269|DRUG: Placebo to LFF269
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Oxybate in Schizophrenia With Insomnia
Status: COMPLETED
Conditions: Schizophrenia|Insomnia Related to Schizophrenia (307.42)
Interventions: DRUG: Sodium Oxybate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study the Oral Bioavailability of a New Combination Formation of Decitabine and Tetrahydrouridine in Healthy Males
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Decitabine|DRUG: Tetrahydrouridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on the Clearance of the Human Papillomavirus and on Cytological Lesions Caused by the Virus
Status: COMPLETED
Conditions: HPV-related Cytological Abnormalities on PAP Smear (LSIL)
Interventions: DIETARY_SUPPLEMENT: probiotic drinkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Durations of Treatment With Grazoprevir (MK-5172) in Combination With Ribavirin in Participants With Chronic Hepatitis C (MK-5172-039)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of HIFU in TREATMENT OF LOCALIZED PROSTATE CANCER and OF RECURRENCE AFTER RADIOTHERAPY
Status: COMPLETED
Conditions: Prostate Cancer|Ultrasound Therapy
Interventions: PROCEDURE: Radical Prostatectomy|PROCEDURE: High Intensity Focused Ultrasound (HIFU) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site RCT of a Stepped-Care Intervention for Emergency Department Patients With Panic Attacks and Panic Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Panic Attacks and Disorders
Interventions: BEHAVIORAL: Stepped Care Intervention (STEP)|DIAGNOSTIC_TEST: Screening only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raloxifene for Prevention of Bone Loss in Postmenopausal Patients Receiving Chronic Corticosteroid Therapy
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: raloxifene|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder|Depression|Prolonged Grief Disorder
Interventions: BEHAVIORAL: Narrative Exposure Therapy/Interpersonal Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of ABT-335 in Combination With Simvastatin in Subjects With Multiple Abnormal Lipid Levels in the Blood
Status: COMPLETED
Conditions: Dyslipidemia|Coronary Heart Disease|Mixed Dyslipidemia
Interventions: DRUG: ABT-335|DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT