pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Open-label Trial to Evaluate the Safety and Efficacy of Chloral Hydrate in Patients With Severe Insomnia
Status: RECRUITING
Conditions: Insomnia|Insomnia Chronic|Chloral Hydrate
Interventions: DRUG: Chloral Hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discrete Versus Rhythmic Gait Training
Status: COMPLETED
Conditions: Stroke|Cerebral Vascular Disorders
Interventions: PROCEDURE: Novel Protocol|PROCEDURE: Standard Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Glycemic Index and Load Diet for the Treatment of Acne
Status: COMPLETED
Conditions: Acne Vulgaris|Diet Modification
Interventions: OTHER: Normal diet|OTHER: Low glycemic diet|DRUG: Adapalene 0.1% Gel|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vibratory Perturbation-based Pinch Task Training for Stroke Patients
Status: COMPLETED
Conditions: Stroke Rehabilitation
Interventions: OTHER: Vibratory perturbed task-specific movement training|OTHER: Traditional task-oriented facilitation|OTHER: Sensorimotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Preoperative Sintilimab Plus Nab-paclitaxel and Cisplatin in BR-ESCC Patients
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sintilimab|DRUG: Nab paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Anti-inflammatory Treatment in Patients With Acute ACL Tear and Painful Effusions
Status: COMPLETED
Conditions: Anterior Cruciate Ligament
Interventions: DRUG: Gel-One|OTHER: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy
Status: RECRUITING
Conditions: Cognitive Impairment|Cognitive Decline|Radiotherapy Side Effect|Radiotherapy; Complications|Brain Tumor|Memory Impairment|Late Effect of Radiation
Interventions: DRUG: Lithium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clopidogrel for Acute Ischaemia of Recent Onset
Status: COMPLETED
Conditions: Ischemic Cerebrovascular Accident
Interventions: DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Toothpaste and Serum Compared to Standard Fluoride Toothpaste on Gingival Health Over a Six Month Period.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Treatment|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Position at Birth,Placental Transfusion Volume and Cord Clamping
Status: TERMINATED
Conditions: Delay Cord Clamping|Placental Trasfusion
Interventions: OTHER: Position at introitus level|OTHER: Position at Maternal Abdomen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relationship Between the Development of Impaired Glucose Tolerance, the Phenotype of CFLD, and the Risk of Liver Fibrosis
Status: WITHDRAWN
Conditions: CF - Cystic Fibrosis|Cystic Fibrosis-related Diabetes|Cystic Fibrosis Liver Disease
Interventions: DEVICE: Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors
Status: COMPLETED
Conditions: Triple-Negative Breast Cancer|High-grade Serous Ovarian Cancer|Solid Tumors|NUT Midline Carcinoma
Interventions: DRUG: CUDC-907
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychotherapy Effects on Reward Processing in PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Diminished Pleasure|Anhedonia|PTSD|Chronic PTSD|Chronic Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure
Status: COMPLETED
Conditions: Recurrent Implantation Failure
Interventions: DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)
Status: TERMINATED
Conditions: Graft Versus Host Disease|JNS Kinase|Topical Administration
Interventions: DRUG: Ruxolitinib 1.5% cream|DRUG: vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immune-based Combinations in Patients Undergoing Nephrectomy for Locally Advanced ccRCC
Status: RECRUITING
Conditions: Neoplasms|Kidney Neoplasms|Urologic Neoplasms|Urogenital Neoplasms|Female Urogenital Diseases|Urogenital Diseases|Kidney Diseases|Urologic Diseases|Male Urogenital Diseases|Carcinoma|Carcinoma, Renal Cell|Antineoplastic Agents|Immune Checkpoint Inhibitors
Interventions: DRUG: Toripalimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:
Status: COMPLETED
Conditions: Acute Pain|Chronic Pain
Interventions: PROCEDURE: Tap block|PROCEDURE: intravenous Patient controlled analgesia|DRUG: Morphine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy
Status: RECRUITING
Conditions: Myopathy|Phenotypic Abnormality|Genetic Disease
Interventions: DIAGNOSTIC_TEST: Western blot|OTHER: Protein interaction studies|OTHER: Mass Spectometry|OTHER: RNA seq
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: Surfactant instillation|PROCEDURE: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigating Marrow Infiltrating Lymphocytes in Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Urothelial Carcinoma
Interventions: PROCEDURE: Bone Marrow Aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Sealants in Cavitated Enamel Lesions on Occlusal Surfaces in Children
Status: COMPLETED
Conditions: Fissure Sealants|Oral Hygiene Orientation
Interventions: OTHER: fissure sealant|OTHER: oral hygiene orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Telemedicine to Improve Veteran Sleep Apnea Care
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: BEHAVIORAL: Video Teleconferencing Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Pulmonary Rehabilitation Program in Patients With SARS-CoV-2 Pneumonia
Status: UNKNOWN
Conditions: Covid19|Covid19 Pneumonia|SARS-CoV 2 Pneumonia
Interventions: OTHER: Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wide-Awake Local Anesthesia vs. Regional/General Anesthesia for Flexor Tendon Repair
Status: NOT_YET_RECRUITING
Conditions: Tendon Injury - Hand
Interventions: PROCEDURE: WALANT|PROCEDURE: General/regional anesthesia|DRUG: WALANT Injection|DRUG: Regional Anesthetic Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-Week Study of Plecanatide for CIC (The CIC3 Study)
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Plecanatide|DRUG: Placebo|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saline-Controlled Study of nSTRIDE APS for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: nSTRIDE APS|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Penumbra Smart Coil|DEVICE: Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Tranilast in the Treatment of Cryopyrin-Associated Periodic Syndrome (CAPS)
Status: RECRUITING
Conditions: Cryopyrin-Associated Periodic Syndromes
Interventions: DRUG: Tranilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban for Thromboprophylaxis in High-risk Cancer Patients With Totally Implantable Access Ports
Status: UNKNOWN
Conditions: Rivaroxaban|Thromboprophylaxis|Cancer
Interventions: DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Effect of Ticagrelor Versus Prasugrel Maintenance Dose on Endothelial Function of Peripheral Vessels in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Endothelial Function
Interventions: DRUG: Ticagrelor|DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Malignant Lymphoma (0683-030)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Concentration of the Local Anesthetic Ropivacaine on the Quality of a Ultrasound Guided Intermediate Cervical Block.
Status: COMPLETED
Conditions: Intermediate Cervical Plexus Block for Carotid Endarterectomy
Interventions: DRUG: ropivacaine 0,375%|DRUG: ropivacaine 0,75%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults
Status: RECRUITING
Conditions: Opioid-use Disorder
Interventions: DRUG: XR-B (SUBLOCADETM)|DRUG: XR-NTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Treatment for Eating Disorders Versus CBT-E Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Personalized Treatment for Eating Disorders|BEHAVIORAL: Cognitive Behavioral Therapy for Eating Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumor|Hepatocellular Carcinoma
Interventions: DRUG: TORL-4-500
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AEB071 (a Protein Kinase C Inhibitor) in Patients With CD79-mutant Diffuse Large B-Cell Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: AEB071
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Real Time Analyses of CARdio-RESpiratory Signals to the Diagnosis of Infection in PREterM Infants
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: PROCEDURE: Analysis of the heart rate and respiratory characteristics / Telemonitoring system prototype developed by INSERM U-642
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exposure Therapy Consortium (ETC) for Anxiety Sensitivity
Status: ACTIVE_NOT_RECRUITING
Conditions: Elevated Anxiety Sensitivity
Interventions: BEHAVIORAL: Standard Exposure|BEHAVIORAL: Stress Management Training|BEHAVIORAL: Enhanced Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safinamide in Idiopathic Parkinson's Disease (IPD) With Motor Fluctuations, as add-on to Levodopa
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Safinimide 50-100 mg/day|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of DCL-101 Compared to GoLYTELY
Status: COMPLETED
Conditions: Bowel Preparation Before Colonoscopy
Interventions: DRUG: DCL-101 vs Golytely
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase1, STP7 Cocaine Drug-Drug Interaction Study
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: DRUG: STP7 (mavoglurant) or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19
Status: WITHDRAWN
Conditions: Covid 19 Positive|Corona Virus Infection
Interventions: DRUG: Artemisinin / Artesunate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Combined With Cisplatin-based Chemotherapy as First-line Systemic Therapy in Advanced Penile Cancer
Status: COMPLETED
Conditions: Penile Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Standard of care therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Palatability of 10-day Supplementation With Hemp Oil, Calamari Oil, and Broccoli Extract in Healthy Adults
Status: COMPLETED
Conditions: Diet, Healthy
Interventions: DIETARY_SUPPLEMENT: Standard Process Hemp Oil Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Flow Nasal Cannula Versus High Velocity Nasal Insufflation in Covid-19
Status: UNKNOWN
Conditions: COVID-19|Acute Respiratory Failure
Interventions: DEVICE: High Flow Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Glaukos Trabecular Micro-Bypass Stent in Refractory Open Angle Glaucoma Subjects
Status: COMPLETED
Conditions: Open-Angle Glaucoma
Interventions: DEVICE: Glaucoma Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱ/Ⅲ Clinical Study of Tumor Treating Fields （EFE-P100）Combined With Docetaxel in the Treatment of Stage IV Non-small Cell Lung Cancer Patients With Disease Progression After Platinum-based Chemotherapy and Anti-programmed Death 1（PD-1)/Programmed Cell Death-Ligand 1(PD-L1) Antibody Treatment
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DEVICE: Tumor treating fields（EFE-P100）|DRUG: Docetaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 14 Day Early Bactericidal Activity Study of Nitazoxanide for the Treatment of Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Nitazoxanide|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nabilone Effect on the Attenuation of Anorexia, Nutritional Status and Quality of Life in Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer|Anorexia|Cachexia|Weight Lose
Interventions: DRUG: Nabilone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Cardiopulmonary Exercise Test as an Incentive to Outpatient Cardiac Rehabilitation for Acute Coronary Syndrome Survivors.
Status: NOT_YET_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: information reveal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
Status: ENROLLING_BY_INVITATION
Conditions: Cognition Disorders in Old Age|Cognitive Function|Frailty/Sarcopenia|MCI
Interventions: DEVICE: Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data|DEVICE: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of GSK2881078 in Single and Repeat Doses
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: GSK2881078|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Oral Glucose Tolerance Test (OGTT)|OTHER: Assessment of dietary compliance|OTHER: Stool sampling|OTHER: Sodium Saccharin|OTHER: Placebo|OTHER: Lactisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Imminent Paralysis Following Spinal Cord Trauma or Ischemia by Minocycline: A Multi-center Study in Israel With IDF Primary Care Involvement
Status: UNKNOWN
Conditions: Spinal Tumors, Trauma Patients, Minocycline.
Interventions: DRUG: Minocycline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Falls Among Older Adults in Community Settings
Status: COMPLETED
Conditions: Fall
Interventions: BEHAVIORAL: Tai Ji Quan: Moving for Better Balance|BEHAVIORAL: Multimodal Exercise|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Activity, Safety and Tolerability of ZX-101A in Relapsed/Refractory Hematological Malignancies
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma|Peripheral T Cell Lymphoma|CLL/SLL
Interventions: DRUG: ZX-101A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and COVID-19 Management
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Ddrops® products, 50,000 IU, Oral|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of CNTO 148 in Patients With Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CNTO148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study of the Use of Belantamab Mafodotin (Blenrep®) in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM) in Spain.
Status: UNKNOWN
Conditions: RELAPSED AND/OR REFRACTORY MULTIPLE MYELOMA
Interventions: DRUG: Belantamab mafodotin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Multi-species Probiotic HOWARU® Restore, on Gut Microbiota of Elderly
Status: COMPLETED
Conditions: Elderly|Probiotics|Clostridium Difficile|Gut Microbiota|Fecal Metabolome
Interventions: DIETARY_SUPPLEMENT: HOWARU Restore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Validation of Two Wrist-worn Devices for the Assessment of Energy Expenditure in Cardiac Patients.
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: Fitbit Charge 2|DEVICE: Mio Slice|DEVICE: Oxycon Mobile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4041 in Healthy Volunteers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: AZD4041|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ropivacaine Use in Femoral Nerve Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weeks
Status: COMPLETED
Conditions: Fabry Disease
Interventions: BIOLOGICAL: Pegunigalsidase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BIIL 284 BS on the Pharmacokinetics of Theophylline in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 BS|DRUG: Theophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Parent-mediated Social-communication Therapy for Young Children Living in Poverty in Brazil
Status: UNKNOWN
Conditions: Child Development|Communication, Social|Environmental Exposure
Interventions: BEHAVIORAL: Paediatric Autism Communication Therapy (PACT)|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lisinopril for Renal Protection in Postpartum Preeclamptic Women
Status: WITHDRAWN
Conditions: Microalbuminuria|Preeclampsia
Interventions: DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esketamine Administration on Recovery Quality After Radical Mastectomy
Status: COMPLETED
Conditions: Esketamine and the Quality of Recovery
Interventions: DRUG: Low-dose esketamine infusion|DRUG: High-dose esketamine infusion|DRUG: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Application of Pegvisomant and Octreotide in Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: pegvisomant|DRUG: combination with somatostatin analogue octreotide|DRUG: combination with dopamine agonist cabergoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of L-arabinose in a Meal in Healthy Men
Status: COMPLETED
Conditions: Glucose Metabolism
Interventions: DIETARY_SUPPLEMENT: L-arabinose - effect on glucose metabolism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Effect of Consumption of Fish Oil Encapsulated on Inflammatory Markers in Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Inflammation
Interventions: DIETARY_SUPPLEMENT: fish oil encapsuled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiolabeled Monoclonal Antibody Therapy and Etoposide Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Myelodysplastic Syndrome or Refractory Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: filgrastim|DRUG: etoposide|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: yttrium Y 90 monoclonal antibody M195
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Thoracic-Lumbar Arthrodesis- Implanet Jazz
Status: RECRUITING
Conditions: Spondylolisthesis|Spinal Stenosis|Degenerative Disease
Interventions: OTHER: Prospective follow-up of patients who have received instrumented lumbar arthrodesis supplemented the Implanet Jazz System(TM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monoclonal Antibody Therapy or Biological Therapy in Treating Patients With Chronic Lymphocytic Leukemia or Multiple Myeloma in Remission After Chemotherapy
Status: WITHDRAWN
Conditions: Leukemia|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Mobile Phone Text Messaging Plus Motivational Interviewing: Effects on Breastfeeding, Child Health Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Breastfeeding, Exclusive|HIV Infections
Interventions: BEHAVIORAL: Mobile phone text messaging plus prospective motivational interviewing|BEHAVIORAL: Standard infant feeding counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Erythropoetin Neuroprotection for Neonatal Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease|Hypoplastic Left Heart Syndrome|Transposition of the Great Arteries|Aortic Arch Hypoplasia or Interruption
Interventions: DRUG: Erythropoetin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sorafenib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Multisystemic Therapy|BEHAVIORAL: Home-based, Non-Directive Family Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptomatic Gastroesophageal Reflux Disease: Double Blind Randomized Controlled Study of On-demand Therapy Versus Maintenance Therapy
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Breath Biomarkers for Sleep Loss and Circadian Timing
Status: ACTIVE_NOT_RECRUITING
Conditions: Shift-Work Sleep Disorder|Shift Work Type Circadian Rhythm Sleep Disorder|Sleep Disorders, Circadian Rhythm|Sleep Disorders, Intrinsic|Advanced Sleep Phase Syndrome (ASPS)|Advanced Sleep Phase Syndrome|Advanced Sleep Phase|Delayed Sleep Phase|Delayed Sleep Phase Syndrome|Non-24 Hour Sleep-Wake Disorder|Irregular Sleep-Wake Syndrome
Interventions: BEHAVIORAL: Short Nap Intervention|BEHAVIORAL: No Nap Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gallium-68 PSMA-11 Positron Emission Tomography (PET) Imaging in Patients With Biochemical Recurrence
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ga-68 labeled PSMA-11 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Resveratrol and Acute Exercise on Endothelial Function in Postmenopausal Women
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DRUG: Climara|DRUG: Placebo patch|DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial to Assess the Pharmacokinetics, Safety and Tolerability of Semaglutide in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide 0.5 mg|DRUG: Placebo (semaglutide 0.5 mg)|DRUG: Semaglutide 1.0 mg|DRUG: Placebo (semaglutide 1.0 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Training in Neurodegenerative Diseases (NDD2019)
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: OTHER: CoRe software|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of UE Aerobic Exercise on Exercise Capacity and PA in Patients With Pulmonary Arterial Hypertension.
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension (PAH)
Interventions: OTHER: aerobic exercises|OTHER: active alternating movements for the upper limbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Long-Term Safety Sodium Oligomannate Capsules (GV-971)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Sodium Oligomannate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-2060 in Participants With Chronic and/or End-Stage Kidney Disease (MK-2060-011)
Status: COMPLETED
Conditions: End-Stage Renal Disease|End-Stage Kidney Disease|Kidney Failure, Chronic
Interventions: BIOLOGICAL: MK-2060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observation of Perioperative Outcomes of Robotic Pancreaticoduodenectomy
Status: RECRUITING
Conditions: Pancreaticoduodenectomy
Interventions: PROCEDURE: robotic pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MSC for Occlusive Disease of the Kidney
Status: COMPLETED
Conditions: Atherosclerotic Renal Artery Stenosis|Ischemic Nephropathy|Renovascular Hypertension
Interventions: DRUG: Arterial infusion of autologous mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation for Pediatric Epilepsy
Status: UNKNOWN
Conditions: Epilepsy
Interventions: DEVICE: ear vagus nerve stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Dinoprostone Administration Prior to Intrauterine Device Insertion
Status: COMPLETED
Conditions: IUD Insertion Pain
Interventions: DRUG: Dinoprostone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus Losartan
Status: NOT_YET_RECRUITING
Conditions: Proteinuria
Interventions: DRUG: Losartan|DRUG: Losartan + Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemo-radiotherapy With Capecitabine for Unresectable Locally Advanced Pancreatic Carcinoma
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Capecitabine (Xeloda®)|RADIATION: Localization, simulation and immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: VC004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of MLS LASER Therapy in Patients With Chronic Nonspecific Neck Pain
Status: COMPLETED
Conditions: Chronic Non-specific Neck Pain
Interventions: OTHER: Laser therapy|OTHER: Sham laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D in Diets of Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Infants
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PREMILOC Trial to Prevent Bronchopulmonary Dysplasia in Very Preterm Neonates
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: hydrocortisone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tralokinumab Administered by an Autoinjector in Adults and Adolescents With Moderate to Severe Atopic Dermatitis (INJECZTRA)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tralokinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Deflating the Tracheal Cuff Shorten Weaning Time?
Status: COMPLETED
Conditions: Weaning|Tracheostomy
Interventions: PROCEDURE: Deflating tracheal cuff|PROCEDURE: Deflating tracheal cuff 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Nalbuphine and Magnesium Sulfate on Emergence Agitation in Pediatric
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium
Interventions: DRUG: Nalbuphine Versus Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Gene Therapy for Leber Congenital Amaurosis Caused by RPE65 Mutations
Status: COMPLETED
Conditions: Leber Congenital Amaurosis
Interventions: GENETIC: rAAV2-hRPE65
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Intervention Study of Tangningtongluo on Diabetic Foot Ulcer
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Standardized Western Medicine Treatment|DRUG: Tangningtongluo tablet and cream|DRUG: Tangningtongluo tablet|DRUG: Tangningtongluo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Influence of Externally vs. Internally Focused Exercise on Rehabilitation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Parkinson's disease Sensory Attention Focused Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Safety of Intravenous Tc 99m Tilmanocept and a Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: Tc 99M Sulfur Colloid|DRUG: Tc99m-tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Lixisenatide on Postprandial Lipid Profile in Obese Type 2 Diabetic Patients
Status: TERMINATED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: LIXISENATIDE AVE0010|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pimavanserin for Rigid-compulsive Symptoms in Autism Spectrum Disorder
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Pimavanserin Tartrate 34 Mg ORAL CAPSULE [NUPLAZID]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone for the Treatment of Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Disorder|Insulin Resistance
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Immuno-Oncology for Advanced Non-small Cell Lung Cancer Patients With PD-1 ICI Resistance
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Durvalumab (MEDI4736)|DRUG: Monalizumab (IPH2201)|DRUG: Oleclumab (MEDI9447)|DRUG: Ceralasertib (AZD6738)|DRUG: DOCETAXEL|DRUG: Savolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
Status: COMPLETED
Conditions: Obesity|Sarcopenia|Aging
Interventions: OTHER: DASH diet containing daily intakes of red meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Ultrasound Guided Penile Block vs Pudendal Block for Hypospadias
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Penile Block|PROCEDURE: Pudendal Block|DRUG: Bupivacaine (Block Drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Isoflavone G-2535 (Genistein) in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Recurrent Bladder Carcinoma|Stage I Bladder Cancer AJCC v6 and v7|Stage II Bladder Cancer AJCC v6 and v7|Stage III Bladder Cancer AJCC v6 and v7
Interventions: DRUG: Genistein|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo Administration|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID)
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease
Interventions: DRUG: Ceftriaxone|DRUG: Doxycycline|DRUG: Metronidazole|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW Neonates
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome In Premature Infants
Interventions: DEVICE: Babylog VN500 in HFOV Mode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Skin Infection|Staphylococcal Infections|Staphylococcus Aureus Infection
Interventions: DRUG: Clindamycin|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Single Dose Pharmacokinetics of Two and Proof of Efficacy of One New Etoricoxib Gel Formulation in Participants With Osteoarthritis (MK-0663-168)
Status: COMPLETED
Conditions: Osteoarthritis Pain
Interventions: DRUG: Etoricoxib 75 mg 4% DMSO Gel|DRUG: Etoricoxib 75 mg 4% PG Gel|DRUG: Etoricoxib 150 mg 4% DMSO Gel|DRUG: Etoricoxib 150 mg 4% PG Gel|DRUG: Etoricoxib 163 mg 4% DMSO gel|DRUG: Placebo|DRUG: Etoricoxib 50 mg 4% DMSO|DRUG: Matching Placebo to Etoricoxib 50 mg 4% DMSO Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SpiroGym App-Aided Cough Rehabilitation
Status: RECRUITING
Conditions: Parkinson Disease|Voluntary Peak Cough Strength|mHealth
Interventions: DEVICE: Expiratory muscle strength training + SpiroGym application|DEVICE: Expiratory muscle strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Movicol in Childhood Constipation (ProMotion Study)
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: Polyethylene glycol 3350 NA bicarbonate NaCl KCl (Movicol)|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: End-expiratory Occlusion Test and Lung Recruitment Maneuver to Assess Fluid responsiVeness In Surgical Patients
Status: UNKNOWN
Conditions: Hemodynamic Instability|Surgery|Fluid Overload
Interventions: DIAGNOSTIC_TEST: End-expiratory occlusion test (EEOT)|DIAGNOSTIC_TEST: Lung recruitment manovre (LRM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of High-intensity Interval Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke
Status: COMPLETED
Conditions: Stroke, Ischemic|Cerebrovascular Accident
Interventions: OTHER: High intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT