pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Robot Assisted Virtual Rehabilitation for the Hand Post Stroke (RAVR)
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: DEVICE: Early Robotic/VR Therapy (EVR)|BEHAVIORAL: Dose-Matched Usual Physical Therapy Care|DEVICE: Delayed Robotic/VR Therapy (DVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetics of Prolonged Infusion Meropenem in Cystic Fibrosis (CF) Children
Status: COMPLETED
Conditions: Cystic Fibrosis|Pneumonia|Pseudomonas Aeruginosa Infection
Interventions: DRUG: meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelogenous Leukemia|Non-Hodgkin's Lymphoma|Non-Hodgkin Lymphoma|Hodgkin Disease|Hodgkins Disease|Hodgkin's Disease|Multiple Myeloma|Myelodysplastic Syndrome|Myeloproliferative Neoplasm
Interventions: DRUG: BL-8040|PROCEDURE: Leukapheresis|PROCEDURE: Hematopoietic cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Optimized General Anesthesia Care Reduce Postoperative Delirium?
Status: TERMINATED
Conditions: Hip Fractures|Anesthesia|Delirium
Interventions: DEVICE: cerebral oximeter (Fore-Sight)|DEVICE: depth of anesthesia monitor (BIS)|PROCEDURE: BP management|PROCEDURE: General anesthesia|DRUG: propofol|DRUG: fentanyl|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Chemotherapy and Regenerative Markers of Liver Regeneration After Liver Resection for Liver Metastases
Status: UNKNOWN
Conditions: Liver Regeneration|Liver Metastases
Interventions: PROCEDURE: Liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab In Combination With Debio 1143 In Pancreatic and Colorectal Advanced/Metastatic Adenocarcinoma
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum
Interventions: DRUG: Pembrolizumab|DRUG: DEBIO1143
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Explore the Pharmacokinetics and Relative Bioavailability of Sulfatinib Capsules in Two Different Manufacturers
Status: COMPLETED
Conditions: Relative Bioavailability
Interventions: DRUG: Sulfatinib T capsule|DRUG: Sulfatinib R capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B-type Natriuretic Peptide Guided Therapy to Improve Clinical Outcomes for Patients Undergoing Non-cardiac Surgery
Status: UNKNOWN
Conditions: Surgery|Cardiovascular Complications|Risk Assessment
Interventions: OTHER: BNP guided medical therapy optimisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Carbetocin Versus Oxytocin Plus Misoprostol in Decreasing Blood Loss During Cesarean Section
Status: COMPLETED
Conditions: Blood Loss, Surgical|Intrapartum Hemorrhage
Interventions: DRUG: Oxytocin + misoprostol|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Explore the Safety and Feasibility of Allogeneic Young Plasma Infusion in Older Adults
Status: WITHDRAWN
Conditions: Frailty Syndrome|Heart Failure
Interventions: BIOLOGICAL: Allogeneic Young Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Bedaquiline 100 Milligram (mg) Tablets Administered as Different Test Formulations Compared to the Commercial Tablet Formulation (F001) in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Bedaquiline (Test formulation)|DRUG: Bedaquiline (Reference formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Two Week Nitazoxanidebased Quadruple Regimen
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DRUG: Nitazoxanide|DRUG: Levofloxacin|DRUG: Doxycyclin|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver Function
Status: COMPLETED
Conditions: Hepatic Insufficiency & Healthy Subjects
Interventions: DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Adaptive Physical Activity on Health-related Fitness of Students With Intellectual Disabilitiesdisability
Status: NOT_YET_RECRUITING
Conditions: Intellectual Disability
Interventions: BEHAVIORAL: Adaptive Physical Activity Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of ChimeriVax™-JE and JE Inactivated Mouse Brain Vaccine in Children of Descending Age
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: ChimeriVax™-JE|BIOLOGICAL: Japanese Encephalitis Inactivated Mouse Brain Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Noninvasive Ventilation Breathing Test Guiding Weaning in Patients With Acute Hypoxic Respiratory Failure
Status: RECRUITING
Conditions: Acute Hypoxic Respiratory Failure
Interventions: PROCEDURE: Noninvasive ventilation breathing test guiding sequential invasive Ventilation and noninvasive ventilation weaing protocol|PROCEDURE: The standard SBT guiding weaning group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance Dependents
Status: NOT_YET_RECRUITING
Conditions: Substance Dependence|Executive Function Disorder|Transcranial Alternating Current Stimulation
Interventions: DEVICE: Transcranial alternating current stimulation-true stimulus|DEVICE: Transcranial alternating current stimulation-sham stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raloxifene for Women With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: raloxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Multimodal Physical Therapy in Migraine
Status: RECRUITING
Conditions: Migraine|Musculoskeletal Neck Pain|Musculoskeletal Disorder of the Neck|Chronic Migraine|Episodic Migraine
Interventions: PROCEDURE: Multimodal Physical therapy approach plus usual care|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Neuroimaging Evaluation of the Central Nervous System Biological Changes Associated With Efavirenz Therapy and Switch to an Elvitegravir-based Regimen
Status: COMPLETED
Conditions: HIV Disease
Interventions: DRUG: Stribild (elvitegravir, cobicistat, emtricitabine and tenofovir)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Proprioceptive Training on Plantar Pressure, Balance, Posture and Gait in Individuals With Diabetes Mellitus Type 2
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Proprioceptive Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coffee and Real-time Atrial and Ventricular Ectopy
Status: COMPLETED
Conditions: Premature Atrial Contractions|Premature Ventricular Contractions
Interventions: BEHAVIORAL: Start: On Caffeine|BEHAVIORAL: Start: Off Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: bevacizumab|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coldplay Cryoablation of Dysplastic Squamous Tissue in Patients With Esophageal Squamous Cell Dysplasia
Status: COMPLETED
Conditions: Esophageal Squamous Cell Dysplasia
Interventions: DEVICE: CryoBalloon Focal Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Children and Adolescents With Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo|DRUG: Topical corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COMPARISON OF KOHLI AND FOLEY CATHETERS IN SUPRAPUBIC CATHETER PATIENTS
Status: UNKNOWN
Conditions: Catheter Infection|Complications; Catheter
Interventions: DEVICE: Kohli vs Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African Men
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infection|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Men Making a Difference HIV/STD Risk Reduction Intervention|BEHAVIORAL: Health Promotion Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Outflow Facility AIT vs Microshunt
Status: COMPLETED
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: Pneumatonometry after microshunt implantation|DIAGNOSTIC_TEST: Pneumatonometry after ab interno trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Single Injection of IVS-3001- Anti - HLA-G CAR-T cells|DRUG: Fludarabine phosphate|DRUG: Cyclophosphamide|PROCEDURE: leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia
Status: NOT_YET_RECRUITING
Conditions: Bronchopulmonary Dysplasia|Gastroesophageal Reflux
Interventions: OTHER: Transpyloric tube feeding|OTHER: Gastric tube feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty
Status: COMPLETED
Conditions: Stable Angina|Coronary Stenosis
Interventions: DEVICE: FFR - guided DEB angioplasty|DEVICE: Provisional bare metal stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of PQ Grass 27600 SU
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: PQ Grass|DRUG: Placebo Option 1|DRUG: Placebo Option 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome.
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: XP13512 (GEn)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Midodrine and Atomoxetine for Neurogenic OH
Status: COMPLETED
Conditions: Neurogenic Orthostatic Hypotension
Interventions: DRUG: Midodrine|DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacological Treatment in Women With Female Sexual Interest/Arousal Disorder (FSIAD).
Status: UNKNOWN
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: Tadalafil 1,5 mg oral tablets|DRUG: Placebo oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2405319 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2405319|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks
Status: COMPLETED
Conditions: Anesthesia, Local|Pain, Postoperative
Interventions: DEVICE: Short-term ON-Q|DEVICE: Short-term ON-Q|DRUG: Short-term ON-Q|DEVICE: Long-term ON-Q|DEVICE: Long-term ON-Q|DRUG: Long-term ON-Q
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease 3
Status: UNKNOWN
Conditions: Angina Pectoris|Atherosclerosis|Coronary Artery Disease|Myocardial Ischemia
Interventions: DIAGNOSTIC_TEST: Head to head comparison: Rubidium vs 15O-water PET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Potential for Dentine Discoloration of Silver Diamino Fluoride Associated With Potassium Iodide
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: PROCEDURE: Silver Diamine Fluoride with Potassium Iodide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Early Laser Treatment for Diabetic Eye Disease in China : A Pilot Randomized Trial
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: PROCEDURE: Pan-retinal photocoagulation laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Use
Interventions: PROCEDURE: SZMN Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Mulligan Therapy Effects In Healthy Subjects With Induced Vertigo
Status: COMPLETED
Conditions: Vertigo
Interventions: PROCEDURE: sustained natural apophyseal glides|PROCEDURE: SHAM SNAG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis
Status: NOT_YET_RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Meropenem|DRUG: Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor Cells as an Early Predictive head-and -Neck Squamous-cell Carcinoma
Status: UNKNOWN
Conditions: Metastatic Head-and-neck Squamous-cell Carcinoma
Interventions: OTHER: Blood analysis by EPISPOT and CellSearch®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES
Status: RECRUITING
Conditions: Diastolic Dysfunction|Systolic Dysfunction|Diastolic Heart Failure
Interventions: DRUG: Sulforaphane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiation Following Percutaneous Balloon Aortic Valvuloplasty to Prevent Restenosis
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: External beam radiation therapy|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib (AZD9291) pemetrexed cisplatin or carboplatin|DRUG: Placebo for osimertinib (AZD9291) pemetrexed cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect and Safety of Idoform Plus on Bowel Side Effects in Healthy Subjects Treated With Amoxicillin/ Clavulanate
Status: WITHDRAWN
Conditions: Diarrhoea
Interventions: DIETARY_SUPPLEMENT: Idoform Plus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tofacitinib Combined With Chidamide in R/R ENKTCL
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: DRUG: tofacitinib|DRUG: chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Pilot Study of the Impact of Nasal Breathing During the Administration of Inhaled Corticosteroids by Inhalation Chamber in Asthmatic Children Ages Between 1 and 4-year-old
Status: TERMINATED
Conditions: Asthma in Children
Interventions: OTHER: Corticosteroids inhalation|OTHER: Corticosteroids inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAMe Trial for Patients With Alcoholic Cirrhosis
Status: RECRUITING
Conditions: Alcoholic Cirrhosis
Interventions: DRUG: Placebo|DRUG: SAMe 400 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Tolerability of Tyrosine Adsorbed Ragweed Pollen Allergoid With MPL (Monophosphoryl Lipid A)
Status: WITHDRAWN
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: RagweedMATAMPL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Pantoprazole 40 mg DR Tablets and Protonix 40 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pantoprazole 40 mg DR Tablet vs. Protonix 40 mg DR Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3/Safety & Efficacy of Esomeprazole in Infants
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Open Label Run In Esomeprazole|DRUG: Double Blind Esomeprazole|DRUG: Double Blind Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Sedation Depth Monitoring for Cognitive Functions and Early Rehabilitation After Major Joints Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Total Knee Replacement Surgery
Interventions: DEVICE: Dräger Infinity Delta series monitor (Dräger, Germany) with Covidien BIS LoC 2 channel module and BIS Quatro (4 electrodes) sensor (Covidien, Ireland)|DEVICE: Dräger Infinity Delta series monitor (Dräger, Germany) with Covidien BIS LoC 2 channel module and BIS Quatro (4 electrodes) sensor (Covidien, Ireland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT on T-REX Twente Regimen Effects on Quality of Life and Mobilisation for Cardiac Surgery Patients After Sternotomy
Status: RECRUITING
Conditions: Sternotomy|Cardiovascular Diseases|Physical Inactivity|Quality of Life|Surgery
Interventions: BEHAVIORAL: T-REX Twente precautions|BEHAVIORAL: Usual (restrictive) sternal precautions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Resistance Exercise and Hydrolyzed Collagen Supplementation
Status: COMPLETED
Conditions: Diet|Food|Nutrition
Interventions: DIETARY_SUPPLEMENT: Consumption of three different doses of hydrolyzed collagen (HC) with resistance exercise|DIETARY_SUPPLEMENT: Consumption of two different doses of hydrolyzed collagen (HC) with reistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of a Glycogen Synthase Kinase 3 (GSK3) Inhibitor in Patients With Alzheimer´s Disease
Status: COMPLETED
Conditions: Alzheimer´s Disease
Interventions: DRUG: NP031112|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Music Listened By Patients With Moderate Dental Anxiety During The Restoration Of Occlusal Caries
Status: COMPLETED
Conditions: Dental Anxiety|Music|Physical Stress
Interventions: BEHAVIORAL: music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Presurgical Therapy With Lapatinib to Explore Molecular Determinants of Response to EGFR/erbB2 Targeted Therapy
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Volumes of Durolane in Knee OA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Durolane 3 ml, Durolane 4,5 ml, Durolane 6 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Complementary Therapies in Men Receiving Radiation Therapy for Prostate Cancer: A Feasibility Trial
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Reiki & Relaxation Response Therapy with Cognitive Restructuring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Motor & Autonomic Concomitant Health Improvements With Neuromodulation & Exercise Training: An SCI RCT
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bladder|Neurogenic Bowel
Interventions: DEVICE: Transcutaneous Spinal Cord Stimulation|DEVICE: SHAM (low-intensity) Transcutaneous Spinal Cord Stimulation|DEVICE: Activity-Based Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
Status: RECRUITING
Conditions: Cancer|Breast Cancer|Endometrial Cancer|Metastatic Cancer|Advanced Solid Tumor
Interventions: DRUG: ALTA2618
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Adults With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2963016|DRUG: Lantus|DRUG: OAMs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Rituximab With or Without Lenalidomide or Cyclophosphamide in Treating Patients With Symptomatic Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehospital Advanced Diagnostics and Treatment of Acute Stroke
Status: UNKNOWN
Conditions: Ischemic (Brain) Stroke|Hemorrhagic Stroke|TIA, Brain
Interventions: OTHER: Prehospital diagnosis and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Bioequivalence Study to Compare Two 2 mg/ml Liposomal Amphotericin B Injections in Healthy Subjects
Status: COMPLETED
Conditions: Normal Healthy Subjects
Interventions: DRUG: Liposomal Amphotericin B|DRUG: AmBisome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Investigate the Safety and Efficacy of Undiluted Intravenous Infusion of I.V.-Hepabig Inj.
Status: RECRUITING
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Undiluted I.V.-Hepabig inj(GC5103)|BIOLOGICAL: Diluted I.V.-Hepabig inj(GC5103)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates
Status: RECRUITING
Conditions: Red Blood Cells(RBC)|Acute Respiratory Distress Syndrome (ARDS)
Interventions: OTHER: conventional treatment with RBC transfusion|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Ascending Dose Comparison of MVT-100 to Definity in Healthy Volunteers
Status: RECRUITING
Conditions: Heart Diseases
Interventions: DIAGNOSTIC_TEST: Echocardiogram|DRUG: MVT-100|DRUG: Definity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lidocaine Patch for Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Neck Pain, Posterior
Interventions: DRUG: Lidocaine patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Implementation Through Dynamic Adaptations (MIDAS) Suicide Prevention 2.0 Clinical Telehealth
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicidal Self-directed Violence|Suicidal Preparatory Behavior
Interventions: BEHAVIORAL: Academic Detailing (AD)|BEHAVIORAL: LEAP|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prediction of Severity of Liver Disease Non Alcoholic Fatty Liver Disease in Patients With Suspected NAFLD by a 13C Octanoate Breath Test
Status: UNKNOWN
Conditions: NAFLD
Interventions: DEVICE: BreathID - Breath Test - 13C Octanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: 26 Week Open Label Study Evaluating Single IA Injection of DUROLANE SJ for Treatment of Osteoarthritis Pain of the Ankle
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Durolane SJ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: DONEPEZIL HYDROCHLORIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: AZD1656|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System
Status: RECRUITING
Conditions: Central Nervous System Neoplasm|Cranial Nerve Disorder|Metastatic Malignant Neoplasm in the Brain
Interventions: DRUG: Ferumoxytol|DRUG: Gadolinium|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of the Daily Doxycycline Pre-exposure Prophylaxis (PrEP) on the Incidence of Syphilis, Gonorrhoea and Chlamydia
Status: ACTIVE_NOT_RECRUITING
Conditions: STIs Prevention
Interventions: DRUG: Doxycycline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining Cereals With Pulses - Reduced Gastrointestinal Symptoms?
Status: COMPLETED
Conditions: Unidentified Gastrointestinal Symptoms Following Pulses Consumption
Interventions: DIETARY_SUPPLEMENT: Pulses and cereals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue Sarcoma
Status: WITHDRAWN
Conditions: Stage II Adult Soft Tissue Sarcoma|Stage IIA Adult Soft Tissue Sarcoma|Stage IIB Adult Soft Tissue Sarcoma|Stage IIC Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: Fluorothymidine F-18|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurofeedback Enhanced Cognitive Reappraisal Training
Status: RECRUITING
Conditions: Anxiety|Social Anxiety Disorder|Panic Disorder|Generalized Anxiety Disorder
Interventions: OTHER: Functional magnetic resonance imaging (fMRI) with Veritable-NF|OTHER: fMRI with Sham-NF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pretreatment Assessment of Oropharynx Ans Soft Palate Radiofrequency Surgery - a Multi-center Study
Status: COMPLETED
Conditions: Snoring
Interventions: PROCEDURE: Interstitial soft palate surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy
Status: COMPLETED
Conditions: Pulmonary Embolism|Acute Pulmonary Embolism|Sub-massive Pulmonary Embolism|Massive Pulmonary Embolism|Pulmonary Thromboembolism
Interventions: DRUG: recombinant tissue plasminogen activator|DEVICE: EKOS EkoSonic Endovascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Response Modifier in the Treatment of Hematologic Malignancies
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|Multiple Myeloma|Chronic Lymphocytic Leukemia
Interventions: DRUG: 852A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Oral Lichen Planus
Interventions: DRUG: erythropoietin|DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 177-Lutetium-PSMA Before Stereotactic Body Radiotherapy for the Treatment of Oligorecurrent Prostate Cancer, The LUNAR Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligometastatic Prostate Carcinoma|Prostate Adenocarcinoma|Recurrent Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Lutetium Lu-177 PNT2002|OTHER: Quality-of-Life Assessment|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: DRUG: imiquimod|PROCEDURE: Ablative or excisional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine and Oxaliplatin in Treating Patients With Metastatic Cancer
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Brain Radiotherapy (WBRT) Versus WBRT and Integrated Boost Using Helical Tomotherapy for Multiple Brain Metastases
Status: UNKNOWN
Conditions: Brain Metastases
Interventions: RADIATION: whole brain radiotherapy|RADIATION: whole brain radiotherapy with simultaneous boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI
Status: RECRUITING
Conditions: CA-AKI - Contrast-Associated Acute Kidney Injury|Coronary Artery Disease|Acute Coronary Syndrome|Adrenergic Receptor Antagonist Adverse Reaction
Interventions: DRUG: Phentolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RCT - Epidural Anesthetic Cocktail Following Endoscopic Lumbar Discectomy
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Epidural Anesthetic Cocktail|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)
Status: RECRUITING
Conditions: T2DM (Type 2 Diabetes Mellitus)|Metformin|SGLT2-Inhibitors
Interventions: DRUG: Tofogliflozin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forty Five Patients With Multiple Sclerosis Recieved Vestibular Rehabilitation and Balance Training
Status: COMPLETED
Conditions: Neurologic Disorder
Interventions: OTHER: Cawthorne Cooksey exercises|OTHER: Vestibular habituation exercises|OTHER: Balance exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine and Gemcitabine Combination In Platinum Resistant Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Vinorelbine and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of Comprehensive Intervention for PED Based on Neuroregulatory Mechanism
Status: RECRUITING
Conditions: Post-extubation Dysphagia
Interventions: OTHER: Comprehensive Intervention or Comprehensive Intervention Combined with Electrical vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telotristat Etiprate for Carcinoid Syndrome Therapy
Status: COMPLETED
Conditions: Carcinoid Syndrome
Interventions: DRUG: Telotristat etiprate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Q301 in Moderate to Severe Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: Q301 Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Anti-oxidant Astaxanthin in Insulin-resistant Subjects
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Astaxanthin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation
Status: TERMINATED
Conditions: Immune System Disorder
Interventions: DRUG: Isatuximab SAR650984|DRUG: Acetaminophen (paracetamol) or equivalent|DRUG: Ranitidine or equivalent|DRUG: Diphenhydramine or equivalent|DRUG: Methylprednisolone or equivalent|DRUG: Montelukast or equivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventional Devascularization Plus HVPG-Guided Carvedilol Therapy vs TIPS
Status: UNKNOWN
Conditions: Gastric Varices Bleeding|Liver Cirrhoses
Interventions: PROCEDURE: interventional devascularization|PROCEDURE: TIPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: May the Risk of PHLF be Predicted With Preoperative Liver Gadoxetate MRI
Status: RECRUITING
Conditions: MRI|Liver Resection|Liver Failure as A Complication of Care
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
Status: NOT_YET_RECRUITING
Conditions: Periodontal Pocket
Interventions: DRUG: Bromelain gel|DRUG: chlorhexidine gel|PROCEDURE: SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylene Blue on Perioperative Organ Function in Patients With Obstructive Jaundice
Status: UNKNOWN
Conditions: Jaundice
Interventions: DRUG: Saline|DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Virtually Delivered Exercise Intervention To Mitigate Cognitive Deficits From Radiotherapy In AYAs With Brain Tumors
Status: SUSPENDED
Conditions: Brain Tumor|Brain Cancer
Interventions: BEHAVIORAL: Standard Fitbit Program|BEHAVIORAL: Virtual Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults of Retirement Age
Status: COMPLETED
Conditions: Healthy Older Adults
Interventions: DEVICE: tDCS|DEVICE: sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Usher Syndrome Type 2|Usher Syndrome Type 3
Interventions: DRUG: NT-501|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT on the Neurobehavioral Effects of Fruits and Vegetables in Shanghai Children
Status: NOT_YET_RECRUITING
Conditions: Cognitive Function|Mood Disorders|Attention-deficit
Interventions: DIETARY_SUPPLEMENT: F&V|DIETARY_SUPPLEMENT: No F&V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DEVICE: Active rTMS Condition|DEVICE: rTMS Location Control Condition|DEVICE: rTMS Frequency Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation(IRE) For Unresectable Rectal Neoplasms
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Opioid Misuse Through Safe Opioid Use Agreements Between Patients and Surgical Providers
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Use|Inguinal Hernia|Ventral Hernia
Interventions: OTHER: Opioid Use Agreement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Ozanimod|DRUG: Gemfibrozil|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computer-aided Detection for Colonoscopy
Status: UNKNOWN
Conditions: Compare Between Computer-assisted Colonoscopy and Standard Colonoscopy
Interventions: DEVICE: Computer-aided detection|DEVICE: Standard colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Pegylated Liposomal Doxorubicin and Docetaxel in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: pegylated liposomal doxorubicin hydrochloride|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Treatment for Back Pain
Status: COMPLETED
Conditions: Back Pain|Lumbar Pain|Thoracic Pain|Somatic Dysfunction|Fascial Distortion
Interventions: OTHER: Osteopathic Manipulative Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT