pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Hepatitis B Vaccine in Chronic Kidney Disease Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Hepatitis B
Interventions: BIOLOGICAL: Sci-B-Vac Hepatitis B Vaccine|BIOLOGICAL: Engerix B Hepatitis B Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fetoscopic Endoluminal Tracheal Occlusion (FETO) With Smart-TO
Status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: PROCEDURE: FETO with Smart-TO balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Simultaneous Use of Supraclavicular and Distal Blocks
Status: COMPLETED
Conditions: Orthopaedic Disorders|Nerve Block|Anaesthesia
Interventions: PROCEDURE: intravenous cannulation.|PROCEDURE: Supraclavicular block and ultrasound-guided ulnar, median and radial nerve blocks.|DEVICE: Intravenous cannulation.|DEVICE: Routine ASA monitoring|DRUG: Premedication midazolam|DRUG: Lidocaine|DRUG: Epinephrine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study for Evaluation of Immunogenicity and Reactogenicity of Fluarix/Influsplit SSW 2012/2013 in People Aged 18 Years and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix/Influsplit SSW 2012-2013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade|DRUG: Melphalan|DRUG: Prednisone|DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Patients With Hip Dysplasia, Mid-Term Lower Extremities and Spine After Hip Arthroplasty Natural Course
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Myocardial Infarction
Interventions: PROCEDURE: Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Extragonadal Germ Cell Tumor|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: dexamethasone|DRUG: etoposide|DRUG: ifosfamide|OTHER: high-dose chemotherapy with autologous stem cell rescue|OTHER: laboratory biomarker analysis|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Reuteri in Children With Constipation
Status: UNKNOWN
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hepatic Pharmacokinetics for Grazoprevir (MK-5172) in Participants With Chronic Hepatitis C (MK-5172-022)
Status: WITHDRAWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peg-Interferon|PROCEDURE: Liver Samples from FNA|PROCEDURE: Liver Samples from CNB|PROCEDURE: Blood Samples|DRUG: Ribavirin|DRUG: 800 mg Grazoprevir|DRUG: 100 mg Grazoprevir|PROCEDURE: Liver samples from CNB and FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of GTx-758 on Total and Free Testosterone Levels in Men With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: GTx-758 1000mg|DRUG: Lupron Depot|DRUG: GTx-758 2000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arogya Sangama: 3 Way Partnership of People, Providers, and Panchayat for Health
Status: RECRUITING
Conditions: Health Care Utilization|Health Care Seeking Behavior|Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Arogya Sangama
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DEVICE: PEMF|DEVICE: Hot pack|DEVICE: TENS|DEVICE: Sham PEMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer-Aided Design/Manufacturing for Le Fort I Osteotomy and 3D-customized Titanium Plate in Orthognathic Surgery
Status: COMPLETED
Conditions: Le Fort; I
Interventions: PROCEDURE: Le Fort I osteotomy using CAD CAM surgical guide and 3Dcustomized plate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear
Status: COMPLETED
Conditions: Ocular Physiology
Interventions: DEVICE: Senofilcon A contact lenses (TEST)|DEVICE: Delefilcon A contact lenses (CONTROL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Bevacizumab and Sunitinib in Metastatic Renal Cell Carcinoma Patients
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: Bevacizumab and Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care Settings
Status: COMPLETED
Conditions: HIV Infections|Adolescent Development|Care Eliciting Behavior|Patient Non-Compliance|Patient Refusal of Treatment
Interventions: BEHAVIORAL: Competency: 12-Item Motivational Interviewing (MI) Coach Rating Scale (CRS)|BEHAVIORAL: Randomized Guided Development of COPs with an internal facilitator after one year of implementation.|BEHAVIORAL: CoP development without internal facilitation.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of Proteomic Analyses for Allergic Asthma and Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic|Asthma, Allergic
Interventions: BIOLOGICAL: Classification as "asthmatic" or "rhinitis only" via proteomic analysis|BIOLOGICAL: Classification as "asthmatic" or "rhinitis only" according to a metacholine test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Blood Flow Rate on Dialysis Recovery Time in Patients Undergoing Maintenance Hemodialysis
Status: COMPLETED
Conditions: ESRD|Fatigue|Hemodialysis-Induced Symptom
Interventions: OTHER: Blood Flow Rate Reduction|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Feasibility of De-prescribing Rounds in a Singapore Rehabilitative Hospital- a Pilot Randomized Controlled Trial
Status: UNKNOWN
Conditions: Deprescribing|Multi-disciplinary|Rounds
Interventions: OTHER: Weekly MDT deprescribing rounds for certain drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of CPM Usage Following Arthroscopic Acetabular Labral Repair
Status: COMPLETED
Conditions: Femoro Acetabular Impingement|Pain, Postoperative|Hip Labral Tear
Interventions: DEVICE: Continuous Passive Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whole-body Vibration on the Ankle Joint, Plantar Pressure, and Running Paramethers
Status: COMPLETED
Conditions: Range of Motion|Running|Gait
Interventions: DEVICE: LADY 1 Pro, New Life Balance|OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Motivational Interviewing on Return to Work in People on Sick Leave Due to Musculoskeletal Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Disease|Musculoskeletal Pain
Interventions: BEHAVIORAL: Motivational interview|BEHAVIORAL: Stratified vocational advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Gastric Feeds|PROCEDURE: Jejunal Feeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance of All-ceramic Posterior Crowns. A Randomized, Prospective Clinical.
Status: COMPLETED
Conditions: Dental Prosthesis Failure
Interventions: COMBINATION_PRODUCT: IPS e.max CAD, Ivoclar Vivadent|COMBINATION_PRODUCT: BruxZir, Glidewell|COMBINATION_PRODUCT: BruxZir*, Glidewell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Reflex Response During Temporary Stimulation and Inhibition of Chemoreceptors of Carotid Bodies - a Pilot Study
Status: COMPLETED
Conditions: Heart Failure|Peripheral Chemoreceptor Hypersensitivity
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Glycemic Control in Diabetic Patients in Hemodialysis Using Continuous Glucose Monitoring (CGM)
Status: COMPLETED
Conditions: Hemodialysis|Type1diabetes|Type2Diabetes
Interventions: DEVICE: Access to CGM data (Dexcom G6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of EverFlex Stent to Treat Symptomatic Femoral-popliteal Atherosclerosis
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Claudication
Interventions: DEVICE: PROTÉGÉ® EverFlex™ Self-Expanding Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome
Status: UNKNOWN
Conditions: Marfan Syndrome
Interventions: DRUG: Losartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrashort Cognitive Behavioral Intervention for Tokophobia- A Prospective Randomized Single Blinded Controlled Trial
Status: UNKNOWN
Conditions: Specific Phobia
Interventions: BEHAVIORAL: CBT|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG
Status: RECRUITING
Conditions: Childhood Glioblastoma
Interventions: DRUG: depletion of regulatory T cells|PROCEDURE: reoperation|BIOLOGICAL: cancer vaccine|BIOLOGICAL: checkpoint blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Evaluating the Safety and Efficacy of Total Endovascular Aortic Arch Repair
Status: UNKNOWN
Conditions: Aortic Dissection|Aortic Arch Aneurysm|Ulcer|Pseudoaneurysm
Interventions: PROCEDURE: Endovascular Aortic Repair|PROCEDURE: Total Arch Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy With or Without Rituximab in Treating Patients With Newly Diagnosed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: CHOP regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety of Bifidobacterium Breve PS1 for Infants
Status: COMPLETED
Conditions: Infant Development|Safety Issues
Interventions: DIETARY_SUPPLEMENT: Infant formula supplemented with Bifidobacterium breve PS1|DIETARY_SUPPLEMENT: Infant formula NOT supplemented with Bifidobacterium breve PS1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DCV in the Treatment of Recurrence and Refractory Childhood Solid Tumors
Status: UNKNOWN
Conditions: Unrecognized Condition
Interventions: DRUG: pegylated liposomal doxorubicin, cyclophosphamide, vincristine,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on BI 54903 (Inhaled Corticosteroid) Administered Once Daily or Twice Daily Via Respimat Inhaler in Patients With Asthma Inadequately Controlled on Low Dose Inhaled Corticosteroids
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Placebo matching Respimat|DRUG: Placebo matching Respimat|DRUG: BI 54903 MD|DRUG: BI 54903 HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reinforcing Effects of Marijuana and Opioids
Status: RECRUITING
Conditions: Marijuana Use|Opioid Use
Interventions: DRUG: Marijuana|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacodynamics of SYNB8802v1 in Subjects With History of Gastric Bypass Surgery or Short-bowel Syndrome
Status: COMPLETED
Conditions: Enteric Hyperoxaluria
Interventions: DRUG: SYNB8802v1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Racecadotril plus ORS|DRUG: ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of T- and B-Cell Subpopulations in Membranous Nephropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Membranous Nephropathy|Membranous Nephropathy - PLA2R Induced|Membranous Nephropathy - THSD7A Induced
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Jing-Si Herbal Tea Liquid Packets and Jing-Si Herbal Tang Heng Power Drink
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Marker|Gut Microbiome|Trimethylamine N-oxide|HbA1c|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: JING SI HERBAL TEA LIQUID PACKETS|DIETARY_SUPPLEMENT: JING SI HERBAL TANG HENG POWDER DRINK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telerehabilitation Program in Persistent COVID-19
Status: COMPLETED
Conditions: Coronavirus Infection|Respiratory Disease
Interventions: PROCEDURE: Walking APP Group|PROCEDURE: Functional APP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intratumoral CAN1012(Selective TLR7 Agonist) in Subjects With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Cancer Metastatic
Interventions: DRUG: CAN1012
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder
Status: COMPLETED
Conditions: Narcolepsy|Sleep Apnea, Obstructive|Sleep Apnea Syndromes|Shift-Work Sleep Disorder
Interventions: DRUG: CEP-10953 (Armodafinil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABM-1310 in Patients With BRAF V600-Mutant Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|BRAF V600 Mutation
Interventions: DRUG: ABM-1310
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Hemiparesis|Lower Extremity Paresis
Interventions: DEVICE: Electrical stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate Versus Curcumin in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Glimepiride Tablets|DRUG: glimepiride plus fenofibrate|DRUG: glimepiride plus curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic Pain
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: DRUG: Gabapentin + Morphine|DRUG: Placebo + Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy Versus Manual Lymphatic Drainageon Cellulite Post Liposuction
Status: COMPLETED
Conditions: Cellulite
Interventions: OTHER: Extracorporeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Balance Exercise and Vagus Nerve Stimulation on Weight-shifting Control and Ambulation in Parkinson Disease and Anxiety
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: weight-shifting exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose Tissue Injection in Perianal Fistulas in Crohn´s Disease
Status: UNKNOWN
Conditions: Crohn Disease|Perianal Fistulas|Cell- and Tissue-Based Therapy|Treatment
Interventions: PROCEDURE: Adipose tissue injection|PROCEDURE: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Optimal Operating Table Height for ProSeal-LMA™ Insertion
Status: UNKNOWN
Conditions: Evaluation of Optimal Operating Table Height for Successful Placement of Proseal Laryngeal Mask Airway
Interventions: DEVICE: ProSeal-LMA™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Proper Dosage of Lovastatin and Docetaxel for Patients With Cancer
Status: TERMINATED
Conditions: Any Cancer|Breast Cancer
Interventions: DRUG: Lovastatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging With a Radio Tracer to Guide VT Ablations
Status: COMPLETED
Conditions: Ventricular Tachycardia|Arrhythmia
Interventions: DRUG: 123I-metaiodobenzylguanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual Reality (VR) Therapy on Patients Undergoing Hand Surgery Under Ultrasound-guided Regional Anesthesia
Status: COMPLETED
Conditions: Anesthesia, Local|Surgery|Hand Injuries
Interventions: DEVICE: The Sedakit Oncomfort VR glasses (30-minutes Aqua program)|PROCEDURE: Ultrasound-guided regional nerve block and hand surgery without VR glasses|PROCEDURE: Ultrasound-guided regional nerve block and hand surgery with VR glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of a Daily Smartphone-based Communication Among Postpartum Women on Breastfeeding Rates
Status: COMPLETED
Conditions: Breast Feeding, Exclusive|Post Partum Depression
Interventions: OTHER: Smartphone based communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Different Preoperative Decision Schemes on the Visual Quality After Toric Intraocular Lens Implantation
Status: UNKNOWN
Conditions: Recruitment of Participants
Interventions: PROCEDURE: phacoemulsification and Toric intraocular lens implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: 5Fluorouracil|PROCEDURE: Esophagectomy (minimally invasive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Soft Exoskeleton to Support Forward Leaning and Lifting
Status: COMPLETED
Conditions: Occupational Exposure
Interventions: DEVICE: Placebo LiftSuit Exoskeleton|DEVICE: LiftSuit Exoskeleton (low support level)|DEVICE: LiftSuit Exoskeleton (medium support level)|DEVICE: LiftSuit Exoskeleton (high support level)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal Ulcer
Status: COMPLETED
Conditions: Keratitis|Corneal Ulcer
Interventions: DEVICE: T4020|DEVICE: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Determine the Efficacy of a Taxane and Bevacizumab With or Without Capecitabine as First Line Chemotherapy in Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Taxane, Avastin|DRUG: Taxane, Avastin, Xeloda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: PBM Therapy|DEVICE: PBM Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of GSK1363089 in Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Neoplasms, Gastrointestinal Tract
Interventions: DRUG: GSK1363089 (formerly XL880)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer
Status: RECRUITING
Conditions: HPV|Throat Cancer|Oropharyngeal Carcinoma|Oropharyngeal Cancer|Human Papilloma Virus
Interventions: DIAGNOSTIC_TEST: 18 F-FMISO PET/CT|RADIATION: Radiation|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacubitril 97 mg and Valsartan 103 mg Film-coated Tablets Relative to Entresto 97 mg/103 mg Film-coated Tablets
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Sacubitril and Valsartan-Test product|DRUG: Sacubitril and Valsartan-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Dose Per Fraction Escalation Trial of Hypofractionated IMRT With Temozolomide for Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: RADIATION: Hypofractionated Intensity-Modulated Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Yangxue Qingnao Granules in Preventing Post Thrombolytic Hemorrhage Transformation in Patients With Acute Cerebral Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Acute Ischemic
Interventions: DRUG: Yangxue Qingnao Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MKC-442 in Combination With Other Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emivirine|DRUG: Hydroxyurea|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Body Position Changes on Endotracheal Tube Cuff Pressure in Ventilated Critically Ill Patients
Status: COMPLETED
Conditions: Mechanical Ventilation With Oral Intubation
Interventions: PROCEDURE: cuff pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Best Revascularisation Approach for Posterior Circulation Strokes With Isolated Vertebral Artery Occlusions
Status: COMPLETED
Conditions: Ischemic Stroke|Vertebral Artery Ischemia|Arterial Occlusive Diseases|Vertebrobasilar Insufficiency
Interventions: OTHER: Conservative treatment (CT)|OTHER: Intravenous thrombolysis (IVT)|OTHER: Endovascular thrombectomy (EVT) ± intravenous thrombolysis (IVT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of TALEN and CRISPR/Cas9 in the Treatment of HPV-related Cervical Intraepithelial NeoplasiaⅠ
Status: UNKNOWN
Conditions: Human Papillomavirus-Related Malignant Neoplasm
Interventions: BIOLOGICAL: TALEN|BIOLOGICAL: CRISPR/Cas9
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Subconjuctival Versus Topical Bevacizumab as Adjunct Therapy to Trabeculectomy
Status: COMPLETED
Conditions: Complications of Treatment|Progression
Interventions: PROCEDURE: Phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Primary and Secondary Prevention of Diseases of the Heart and Blood Vessels
Status: COMPLETED
Conditions: Myocardial Infarction|Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack)|Unstable Angina|Angina|Ischaemic Heart Disease
Interventions: DRUG: Acetylsalicylic Acid (Aspirin, BAYE4465)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)
Status: COMPLETED
Conditions: Chronic Hepatic Impairment
Interventions: DRUG: Preladenant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant Recipients
Interventions: DRUG: Dapagliflozin 10 MG|DRUG: Semaglutide, 1.0 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Comparison Feedback to Providers to Improve Hypertension Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Peer Comparison Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients
Status: UNKNOWN
Conditions: Delirium, Postoperative
Interventions: DRUG: Placebo|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: panitumumab|DRUG: carboplatin|DRUG: paclitaxel|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiarrhythmic Effects of Spironolactone in Patients With ICDs
Status: COMPLETED
Conditions: Ventricular Arrhythmias
Interventions: DRUG: spironolactone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.
Status: RECRUITING
Conditions: Cognitive Impairment
Interventions: DRUG: Dexmedetomidine Hydrochloride|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808 100 mg|DRUG: YH4808 100 mg|DRUG: YH4808 300 mg|DRUG: YH4808 300 mg|DRUG: YH4808 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Modalities Interventions Post Supracondylar Humeral Fracture in Pediatrics
Status: RECRUITING
Conditions: Supracondylar Humeral Fracture in Pediatric
Interventions: DEVICE: low level laser ,pulsed electromagnetic field .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.
Status: COMPLETED
Conditions: Apathy|Behavior|Frontotemporal Dementia
Interventions: BEHAVIORAL: Evaluation of Apathy Close to Real Life Situation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Sweet Orange Oil Inhalation in Management of Dental Anxiety and Pain
Status: NOT_YET_RECRUITING
Conditions: Aromatherapy
Interventions: OTHER: sweet orange oil inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-Label Extension of the Phase III Study With Tramiprosate (3APS) in Patients With Mild to Moderate Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Tramiprosate (3APS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Consuming Products Containing Rare Sugars Alongside Sucrose on Glycaemic Response in Healthy Adults
Status: UNKNOWN
Conditions: Glycaemic Response in Healthy Participants
Interventions: OTHER: SUCROSE|OTHER: CONTROL|OTHER: ARA20|OTHER: ARA40|OTHER: TAG20|OTHER: TAG40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Determine the Effect of Efavirenz on the ECG QTcF Interval in Healthy Subjects
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DRUG: Moxifloxacin|DRUG: Placebo|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sotatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ozurdex® 0.7 mg on Improvement of Efficacy of Bevacizumab for Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Non-Ischemic Central Retinal Vein Occlusion
Interventions: DRUG: Active bevacizumab and Sham dexamethasone|DRUG: Active bevacizumab and Active dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety and Immunogenicity Trial of the FLU-M® Tetra
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-M Tetra [Inactivated split influenza vaccine] w/p|BIOLOGICAL: Flu-M Tetra [Inactivated split influenza vaccine] w/o/p|BIOLOGICAL: Ultrix [Inactivated split influenza vaccine]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of DA-6034 and to Demonstrate the Non-inferiority of DA-6034
Status: UNKNOWN
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: DA-6034|DRUG: Rebamipide 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: One-abutment One-time for Immediate Restoration Procedure in the Esthetic Zone
Status: COMPLETED
Conditions: Implant Tissue Failure
Interventions: PROCEDURE: guided surgery|PROCEDURE: conventionnel implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Solar Lentigines Treatment With the Triple Combination Cream
Status: COMPLETED
Conditions: Lentigo
Interventions: DRUG: Triple combination cream|DRUG: Tretinoin 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2.0 mg/kg Sugammadex and Neostigmine at Reappearance of T2 in Chinese and European Subjects (Study 19.4.324)(P05768AM1)(COMPLETED)
Status: COMPLETED
Conditions: Anesthesia, General|Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability and PK of EC-18 After Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Chemotherapy-Induced Neutropenia
Interventions: DRUG: EC-18|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases
Interventions: RADIATION: Dose Escalated Five Fraction Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Treatment for Cannabis Use Disorders in Psychosis
Status: TERMINATED
Conditions: Cannabis Use Disorder|Psychosis
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Fitness in Long-Term Survivors of HPV-related Oropharynx Cancers
Status: WITHDRAWN
Conditions: Oropharynx Cancers
Interventions: OTHER: blood draw|BEHAVIORAL: study questionnaire|OTHER: cardiopulmonary exercise testing (CPET)|OTHER: DXA (dual-energy x-ray absorptiometry) scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain
Status: TERMINATED
Conditions: Scoliosis
Interventions: DRUG: Clonidine|OTHER: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Olaparib in Homologous-recombination Deficient (HRD) Advanced Colorectal Cancer (CRC).
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Olaparib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Trichuris Suis Ova (TSO) as Compared to Placebo in Autism Spectrum Disorder
Status: TERMINATED
Conditions: Autism
Interventions: BIOLOGICAL: Trichuris suis ova|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Pathological Complete Response by Minimal Invasive Biopsy After Neoadjuvant Chemotherapy in Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: vacuum-assisted biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quantitative Requirements of Docosahexaenoic Acid for Neural Function in Children With Phenylketonuria
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DIETARY_SUPPLEMENT: high oleic sunflower oil|DIETARY_SUPPLEMENT: microalgal oil|DIETARY_SUPPLEMENT: microalgal oil|DIETARY_SUPPLEMENT: microalgal oil|DIETARY_SUPPLEMENT: microalgal oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)
Status: COMPLETED
Conditions: Opioid Dependence|Heroin Dependence
Interventions: DRUG: Hydromorphone, Injectable|DRUG: Diacetylmorphine, injectable|DRUG: Hydromorphone, liquid oral|DRUG: Diacetylmorphine, liquid oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Election of the Optimal Moment of Colecistectomy After Mild Biliary Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis, Acute
Interventions: PROCEDURE: Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Therapy With Interferon, Interleukin-2 and BRAF Inhibitor
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Vemurafenib|DRUG: IL-2|DRUG: Interferon Alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Food Effect Study of RV299 in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: RV299|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACTIVATE: Standard Worksite Health Program vs. Activated Consumer
Status: COMPLETED
Conditions: Evidence of Improved Health Status
Interventions: BEHAVIORAL: Counseling in use of health care|BEHAVIORAL: Counseling in diet, exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DRUG: GSK2982772 Modified Release|DRUG: GSK2982772 Immediate Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Lymphadenectomy During Interval Debulking Surgery in Advanced Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Postoperative Complications|Neoadjuvant Therapy|Lymph Node Excision
Interventions: PROCEDURE: lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Coenzyme Q 10 Supplementation Reduce Muscle Pain Caused by Statins? (Cholesterol Lowering Medications)
Status: COMPLETED
Conditions: Statin Induced Myalgia
Interventions: DRUG: Coenzyme Q 10|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID MED Trial - Comparison Of Therapeutics for Hospitalized Patients Infected With COVID-19
Status: TERMINATED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Effectiveness and Safety of a Remote Automated Ultrasound Diagnostic System for Automated Ultrasound Examinations: a Prospective, Multicenter Study
Status: ENROLLING_BY_INVITATION
Conditions: Ultrasound|Thyroid|Carotid Artery|Liver|Gallbladder|Spleen|Pancreas|Kidney
Interventions: DEVICE: Test equipment: Name: Remote automatic ultrasound diagnostic system (Wuhan Cooper Technology Co., Ltd.) Model: CORUS-A30
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Central Retinal Vein Occlusion (CRVO)
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: OTHER: Sham injection|DRUG: Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of DA-8010 in Healthy Subjects
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DRUG: DA-8010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Status: COMPLETED
Conditions: Postoperative Pain|Complications|Satisfaction
Interventions: PROCEDURE: spinal block|PROCEDURE: Perianal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT