pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Daratumumab With Pomalidomide, Dexamethasone, and All-Transretinoic Acid in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: All-trans retinoic acid|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Pain on Cognitive Performance in Young Adults
Status: COMPLETED
Conditions: Pain, Acute|Cognition
Interventions: PROCEDURE: pain delivery with capsaicin and heat|PROCEDURE: distractor delivery with sensory TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Kinesio-Taping and Muscle Energy Technique on Chronic Sacroiliac Joint Dysfunction
Status: UNKNOWN
Conditions: Musculoskeletal Injury
Interventions: OTHER: Kinesiotaping|OTHER: Muscle Energy Technique|OTHER: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Moderate and High-intensity Exercise During Chemotherapy on Muscle Cells in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: OTHER: Low- to moderate intensity strength and endurance training|OTHER: High intensity strength and endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ganovo (Danoprevir) Combined With Ritonavir in the Treatment of SARS-CoV-2 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Danoprevir+Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cresemba® in Treating Chinese Patients With IFD Caused by Aspergillus Species or Other Filamentous Fungi
Status: RECRUITING
Conditions: Invasive Fungal Disease
Interventions: DRUG: Isavuconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Super Saturated Oxygen (SSO2) Therapy in Patients With ST-segment Elevation Myocardial Infarction (STEMI) and Action on Coronary Microcirculation Dysfunction
Status: NOT_YET_RECRUITING
Conditions: STEMI|Coronary Microvascular Dysfunction
Interventions: PROCEDURE: SSO2 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Singida Nutrition and Agroecology Project
Status: COMPLETED
Conditions: Malnutrition
Interventions: BEHAVIORAL: Mentor farmer training (Malawi)|BEHAVIORAL: Mentor farmer training (Singida, Tanzania)|BEHAVIORAL: Mentor farmer visits and facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: S.C. Immunotherapy With BM41 in Patients With Allergic Rhino-conjunctivitis Caused by Birch Pollen
Status: COMPLETED
Conditions: Birch Pollen Allergy|Allergic Rhinoconjunctivitis
Interventions: DRUG: BM41|OTHER: Placebo|DRUG: ALK Alutard SQ Betula verrucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Sutured Gastroplasty With Endomina® Device Versus Standard of Care in Patients With Type 2 Diabetes and Class I Obesity: a Multi-center, Randomized Controlled Trial
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DEVICE: endomina®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of the ConvaTec Engenex® Negative Pressure Wound Therapy Device to Moist Wound Therapy
Status: WITHDRAWN
Conditions: Diabetes|Foot Wound
Interventions: DEVICE: Convatec engenex negative pressure wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pevonedistat and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Pevonedistat|PROCEDURE: transplant|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Title: Povidone-soaked Sutures Versus Ordinary Sutures for Reducing Surgical Site Infection
Status: UNKNOWN
Conditions: Efficacy Povidone Soaked Suture in Reducing Surgical Site Infection
Interventions: OTHER: povidone-soaked suture|OTHER: ordinary suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School
Status: COMPLETED
Conditions: Response to Severe Stress
Interventions: OTHER: Tyrosine-Containing Bar|OTHER: Placebo Bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Impact of WASH on Handwashing Practices Among School Children in Nigeria.
Status: RECRUITING
Conditions: Hand Hygiene
Interventions: BEHAVIORAL: Water, Sanitation and Hygiene Education Against Diarrhoea, Undernutrition and Pneumonia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: sorafenib tosylate|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Interneural Local Anesthetic Spread at the Site of Sciatic Nerve Bifurcation Shorten Block Onset Time?
Status: COMPLETED
Conditions: Post Operative Analgesia|Regional Anesthesia|Sciatic Nerve Block
Interventions: PROCEDURE: Distal|PROCEDURE: Interneural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Relationship Between MDSCs and NK Cells Activity of CHC Patient Treated by DAAs
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ledipasvir-Sofosbuvir|DRUG: Daclatasvir-Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iyengar Yoga Therapy for Dysmenorrhea and Endometriosis
Status: UNKNOWN
Conditions: Secondary Dysmenorrhea|Dysmenorrhea|Dysmenorrhea Secondary|Polycystic Ovary Syndrome|Endometriosis|Fibroid|Menstrual Pain|Menstrual Disorder|Menstrual Discomfort
Interventions: OTHER: Iyengar Yoga Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AVACEN Treatment Method and Postprandial Blood Glucose
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DEVICE: AVACEN 100|DEVICE: AVACEN 100 heat only|DEVICE: AVACEN 100 sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|BIOLOGICAL: Glofitamab|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Obinutuzumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Online Yoga With Facebook After Stillbirth
Status: COMPLETED
Conditions: Stillbirth|Post-traumatic Stress Disorder|Anxiety|Depression
Interventions: BEHAVIORAL: Online Yoga + Facebook|BEHAVIORAL: Online Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft Maturity After Blood Flow Restriction Training in ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction|Bone-Patellar Tendon-Bone Grafting
Interventions: BEHAVIORAL: Blood flow restriction training|BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Obesity and Type 2 Diabetes in High Risk Youth
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: BEHAVIORAL: HEALTH[e]TEEN|BEHAVIORAL: HEALTH[e]TEEN + CST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atherosclerosis Underlying Development Assessed by Intima-Media Thickness in Patients on Rimonabant
Status: TERMINATED
Conditions: Carotid Artery Plaque|Arteriosclerosis|Obesity|Metabolic Syndrome X
Interventions: DRUG: Rimonabant|DRUG: Placebo (for Rimonabant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Obstructive Pulmonary Disease (COPD) Dual Therapy Burden of Illness
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: UMEC/VI|OTHER: FLUT/SAL|OTHER: CAT|OTHER: mMRC|DEVICE: Ellipta|DEVICE: Diskus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV
Status: RECRUITING
Conditions: Hiv|Fatigue|Mobility Limitation
Interventions: BEHAVIORAL: HIIT (intervention)|BEHAVIORAL: CME (active control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compression And Functional Ability After Endovenous Varicose Vein Treatment
Status: COMPLETED
Conditions: Varicose Veins of Lower Limb|Varicose Veins
Interventions: OTHER: Class II compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of LZM012
Status: RECRUITING
Conditions: Psoriasis
Interventions: BIOLOGICAL: LZM012|BIOLOGICAL: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of NMDA-enhancing and Anti-inflammatory Treatments for Ultra-resistant Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: NMDAE plus AIFA|DRUG: NMDAE plus Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Probiotic Products on the Intestinal Barrier Function in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: IBS
Interventions: DIETARY_SUPPLEMENT: Probiotics|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autologous Mesenchymal Stem Cells for the Treatment of Neuromyelitis Optica Spectrum Disorders
Status: COMPLETED
Conditions: Devic's Syndrome|Devic's Neuromyelitis Optica|Devic Syndrome|Devic's Disease|Devic Disease
Interventions: BIOLOGICAL: Autologous mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Vascular Reactivity to Hypothermic Circulatory Arrest With Antegrade Cerebral Perfusion During Aortic Arch Surgery
Status: UNKNOWN
Conditions: Cardiac|Aortic Arch Surgery|Brain Vascular|Neonates|Infants
Interventions: PROCEDURE: aortic arch surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Retrospective, Observational, Multicenter, Study to Collect Clinical Safety and Performance Data on POLYMAILLE®C
Status: COMPLETED
Conditions: Abdominal Vascular Surgery|Peripheral Vascular Surgery|Vascular Prothesis|Aneurysm Abdominal|Aneurysm; Peripheral|Obliterative Arterail Disease
Interventions: DEVICE: Vascular abdominal or peripheral surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Afatinib Combination With Chemotherapy for Stage Ⅱa-Ⅲb NSCLC With EGFR Activating Mutation
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Surgery|EGFR Activating Mutation|Chemotherapy|EGFR TKI
Interventions: DRUG: Neoadjuvant treatment: Afatinib, pemetrexed, gemcitabine, cisplatin, carboplatin|PROCEDURE: Surgical treatment|DRUG: Adjuvant treatment:afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Study on Rh-Endostatin (Endostar®) Continuous Intravenous Infusion and Routine i.v in Combination With GP Regimens for Phase III B/IV Squamous Cell Lung Cancer and Biological Markers Exploration.
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: Endostar continuous intravenous infusion|DRUG: Endostar routine intravenous infusion|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Glenohumeral Joint Steroid Injection Versus Suprascapular Nerve Block in Patients With Frozen Shoulder
Status: RECRUITING
Conditions: Frozen Shoulder
Interventions: PROCEDURE: Glenohumeral joint steroid injection|PROCEDURE: Suprascapular nerve block steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: All-Arthroscopic Versus Mini-Open Repair of Small or Moderate Rotator Cuff Tears
Status: COMPLETED
Conditions: Shoulder Pain|Rotator Cuff Tear
Interventions: PROCEDURE: All-Arthroscopic repair|PROCEDURE: Mini-open repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cidofovir Instillation in Hematopoietic Stem Cell Transplant (HSCT) Recipients With Hemorrhagic Cystitis
Status: WITHDRAWN
Conditions: Cystitis|Bladder Diseases
Interventions: DRUG: Cidofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Psychological Intervention for COVID-19 Survivors With AKI and Caregivers (REPICOV-AKI)
Status: COMPLETED
Conditions: COVID-19|Anxiety|Depressive Symptoms|Acute Kidney Injury
Interventions: BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Of Endovascular Treatment For Acute Posterior Large Vessel Occlusion
Status: SUSPENDED
Conditions: Vertebrobasilar Stroke
Interventions: PROCEDURE: Endovascular treatment|OTHER: Standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety and 1 Year Persistence of Antibodies After Either One or Two Doses of Meningococcal ACWY Conjugate Vaccine in Healthy Children 2 Through 10 Years of Age.
Status: COMPLETED
Conditions: Meningococcal Disease|Infections, Meningococcal
Interventions: BIOLOGICAL: MenACWY-CRM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ixekizumab in the Treatment of Pityriasis Rubra Pilaris (PRP)
Status: COMPLETED
Conditions: Pityriasis Rubra Pilaris
Interventions: DRUG: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Class III Malocclusion and ALT-RAMEC
Status: COMPLETED
Conditions: Face Mask|Rapid Maxillary Expansion|Maxillary Retrognathism
Interventions: DEVICE: Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for first group|DEVICE: Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for second group|DEVICE: Delaire Face Mask (M0774-01, Leone S.p.A., Florence, Italy) for third group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: DRUG: Blinatumomab|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Myocet|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Fludarabine Phosphate|DRUG: Ifosfamide|DRUG: 6-Mercaptopurine|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Prednisolone|DRUG: Tioguanin|DRUG: Vincristine|DRUG: Vindesine|DRUG: Erwinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Bevacizumab in HCC (BCLC-B) Beyond Up-To-Seven Criteria
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma by BCLC Stage
Interventions: DRUG: Bevacizumab Biosimilar QL 1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 35624® Alflorex® in Functional Gastrointestinal Disorders (FGIDs) in Children.
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders|Functional Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: Alflorex®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interventions to Decrease CRE Colonization and Transmission Between Hospitals, Households, Communities and Domesticated Animals
Status: RECRUITING
Conditions: Antibiotic Resistant Infection|Carbapenem-Resistant Enterobacteriaceae Infection
Interventions: BEHAVIORAL: Hospital Cohort Care Intervention at the hospital|BEHAVIORAL: , Household Education Communication Hygiene Intervention, Livestock Antibiotic Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
Status: RECRUITING
Conditions: Coronary Artery Disease|Atherosclerosis|Heart Attack
Interventions: DRUG: Statin|DRUG: Aspirin tablet|DRUG: Nexlizet|DRUG: LEQVIO|DRUG: Vascepa|DRUG: Jardiance|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine as an Adjuvant for Lower Limb Nerve Blocks
Status: UNKNOWN
Conditions: Free Flap Reconstruction
Interventions: DRUG: 0.3% ropivacaine and 50 μg dexmedetomidine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects
Status: ACTIVE_NOT_RECRUITING
Conditions: Sun Damaged Skin
Interventions: DRUG: Sunscreening Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Citric and Malic Acid Found in Pomegranate Juice on Glycaemic Response to White Bread.
Status: COMPLETED
Conditions: Hyperglycemia, Postprandial
Interventions: OTHER: Control|OTHER: Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Nausea and Vomiting, Postoperative
Interventions: DRUG: Aprepitant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Adding Azarga to Prostaglandin Monotherapy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Brinzolamide/Timolol Maleate Fixed Combination (AZARGA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Luvadaxistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve
Status: COMPLETED
Conditions: Mitral Valve Regurgitation|Left Ventricular Dysfunction|Heart Failure
Interventions: DEVICE: Less invasive mitral valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Operation Integrating With Thrombolysis in Basal Ganglion Hemorrhage Evacuation II
Status: UNKNOWN
Conditions: Basal Ganglia Hemorrhage
Interventions: PROCEDURE: Minimally invasive puncture aspiration plus rt-PA|DRUG: Conservative medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Atelectasis|Ventilation, Mechanical
Interventions: DRUG: Pulmozyme (nebulized dornase alpha)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unraveling Back Pain Chronicity: an EMG and EEG Study
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Rapid Arm Movements|DEVICE: Unpleasant stimulus|DEVICE: Vibrotactile stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phytochemicals on "Metabolic Aging" in Older Overweight Adults
Status: UNKNOWN
Conditions: Mitochondrial Functions
Interventions: DIETARY_SUPPLEMENT: fruit/vegetable supplement (FVS)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Von Willebrand Factor in Pregnancy (VIP) Study
Status: UNKNOWN
Conditions: Von Willebrand Diseases
Interventions: OTHER: Use of a postpartum diary and additional blood draws|DRUG: VWF replacement therapy with Wilate|DRUG: Tranexamic acid|OTHER: Use of a postpartum diary and additional blood draws.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vascular Health With Immobilization and Exercise Training
Status: COMPLETED
Conditions: Immobilization, Tonic|Physical Activity
Interventions: OTHER: Immobilization|OTHER: Training with non immobilized leg|OTHER: Exercise training with both legs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stent Retriever Versus Contact Aspiration in Irregular Occlusion Phenotype
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: PROCEDURE: stent retriever thrombectomy|PROCEDURE: contact aspiration thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Antiviral Activity, and Pharmacokinetics of Morphothiadine Mesilate Capsules
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: GLS4|DRUG: RTV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide and PD-1 Inhibitor Plus Anlotinib for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tucidinostat (chidamide), PD-1 inhibitor (tislelizumab), anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study of Denintuzumab Mafodotin (SGN-CD19A) Plus RICE Versus RICE Alone for Diffuse Large B-Cell Lymphoma
Status: TERMINATED
Conditions: Lymphoma, B-cell|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Follicular, Grade 3b|Follicular Lymphoma, Grade 3b
Interventions: DRUG: denintuzumab mafodotin|DRUG: rituximab|DRUG: ifosfamide|DRUG: carboplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of SIM0417 Orally Co-Administered With Ritonavir in Symptomatic Adult Participants With Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: SIM0417|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DWJ1248 With Remdesivir in Severe COVID-19 Patients
Status: TERMINATED
Conditions: Severe COVID-19
Interventions: DRUG: DWJ1248 with Remdesivir|DRUG: Placebo with Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Multipotent Stromal Cell Treatment for Acute Kidney Injury Following Cardiac Surgery
Status: COMPLETED
Conditions: Kidney Tubular Necrosis, Acute
Interventions: BIOLOGICAL: Multipotent Stromal Cells|BIOLOGICAL: Administration of MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Intranasal Esketamine and Its Effects on the Pharmacokinetics of Orally-Administered Midazolam and Bupropion in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: Esketamine|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Anti-inflammatory Effect of Low-Molecular Weight Heparin in Pediatric Cataract Surgery
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Enoxaparin|DRUG: Balanced Salt Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Omega-3 Fatty Acid Supplementation in Children
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: n-3 Fatty Acid supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Rejection of Kidney Transplants
Status: COMPLETED
Conditions: Chronic Antibody-mediated Transplant Rejection
Interventions: DRUG: Bortezomib|DRUG: Plasma exchanges and intravenous immunoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Investigation of 6 Membranes Including Their Physical, Chemical and Biological Properties.
Status: COMPLETED
Conditions: Bone Regeneration|Tissue Engineering
Interventions: OTHER: Biomaterial implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Tranexamic Acid for Bilateral Breast Reduction Surgery
Status: UNKNOWN
Conditions: Hematoma Postoperative|Tranexamic Acid
Interventions: DRUG: Tranexamic acid|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE® VIABAHN® Endoprosthesis for the Treatment of Popliteal Artery Aneurysm (PAA)
Status: COMPLETED
Conditions: Popliteal Artery Aneurysm
Interventions: DEVICE: GORE® VIABAHN® Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lenalidomide for Myelodysplastic Syndrome Refractory to Hypomethylating Agents
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial of 3804-250A in the Prevention of Cold Illnesses
Status: COMPLETED
Conditions: Common Cold
Interventions: DRUG: 3804-250A|DRUG: 3804-291
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxygen Level and Safe Emergence From Anesthesia
Status: COMPLETED
Conditions: Focus of Study is Postoperative Pulmonary Atelectacis
Interventions: PROCEDURE: 30% oxygen|PROCEDURE: 100% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of KA34 in Subjects With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: KA34|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Comprehensive Patient-centered Health Service in Cystic Fibrosis (VEMSE-CF)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: comprehensive patient-centered outpatient health service with multiple components
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Education-based Physical Therapy Approach for Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: OTHER: Physical therapy focus on manual therapy and home-exercises|OTHER: Physical therapy focus on education and supported home exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function
Status: COMPLETED
Conditions: Borderline Hypertension
Interventions: DIETARY_SUPPLEMENT: Epicatechin|DIETARY_SUPPLEMENT: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Meditation Based Lifestyle Modification in Healthy Individuals
Status: COMPLETED
Conditions: Mantra Meditation|Mantra Meditation + Body-Oriented Yoga|Mantra Meditation + Ethical Living|Mantra Meditation + Body-Oriented Yoga + Ethical Living
Interventions: BEHAVIORAL: Ethical Living|BEHAVIORAL: Yoga Exercises|BEHAVIORAL: Mantra Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
Status: ENROLLING_BY_INVITATION
Conditions: Hypertension, Pulmonary|Hypertension;Pulmonary;Primary|Chronic Thromboembolic Pulmonary Hypertension|Vascular Diseases|Lung Diseases
Interventions: DIAGNOSTIC_TEST: Capnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuromuscular Blockade and Surgical Conditions
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DRUG: Profound neuromuscular blockade (Rocuronium, Rocuronium bromide, sugammadex, Bridion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taiwan "Aerosol Box" Versus UMMC "Intubation Box"
Status: UNKNOWN
Conditions: COVID-19|Airway
Interventions: DEVICE: Aerosol Box|DEVICE: Intubation Box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neural Cardiac Therapy for Heart Failure Study (NECTAR-HF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Congestive Heart Failure
Interventions: DEVICE: Implant of investigational device system|PROCEDURE: Titration during the randomization phase|PROCEDURE: Titration after the randomization phase|DIAGNOSTIC_TEST: Blood Draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Start the Conversation: Evaluating Implementation of a Multi-level PrEP Initiative for Black Cisgender Women in Nola
Status: ENROLLING_BY_INVITATION
Conditions: Preexposure Prophylaxis|HIV Infections
Interventions: BEHAVIORAL: GYN Residency Training|BEHAVIORAL: Social Media Campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of the Low-level Laser Therapy (LLLT) on Muscle Strength (MS) of the Patients With Kidneys Failure (KF)
Status: COMPLETED
Conditions: Chronic Kidney Failure
Interventions: DEVICE: 0J LLLT|DEVICE: 4J LLLT|DEVICE: 6J LLLT|DEVICE: 8J LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy
Status: UNKNOWN
Conditions: Graves Disease|Graves Ophthalmopathy|Graves' Ophthalmopathy Worsened
Interventions: DRUG: Antithyroid Drug|PROCEDURE: Total thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-mullerian Hormone (AMH) After Treatment of Endometriomas With Alcohol Sclerotherapy Versus Surgery: Clinical Trial
Status: TERMINATED
Conditions: Endometrioma|Fertility Disorders
Interventions: PROCEDURE: Surgery|PROCEDURE: Sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Endoscopic Tracheal Occlusion for CDH (CDH)
Status: NOT_YET_RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Remote Limb Ischemic Preconditioning For Carotid Artery Stenting
Status: UNKNOWN
Conditions: Stroke|TIA|Coronary Stenosis
Interventions: DEVICE: remote limb ischemic preconditioning|PROCEDURE: Carotid Artery Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Adenosquamous Cell Carcinoma|Endometrial Clear Cell Carcinoma|Endometrial Papillary Serous Carcinoma|Recurrent Endometrial Carcinoma|Stage IIIA Endometrial Carcinoma|Stage IIIB Endometrial Carcinoma|Stage IIIC Endometrial Carcinoma|Stage IVA Endometrial Carcinoma|Stage IVB Endometrial Carcinoma
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome
Status: COMPLETED
Conditions: Lennox-Gastaut Syndrome
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Oral Eluxadoline Administered to Pediatric Participants With Irritable Bowel Syndrome With Diarrhea (IBS-D)
Status: ENROLLING_BY_INVITATION
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: 25mg Eluxadoline|DRUG: 100mg Eluxadoline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-threshold Photocoagulation of Diabetic Macular Oedema
Status: WITHDRAWN
Conditions: Diabetic Macular Oedema
Interventions: DEVICE: PASCAL Laser, Green Laser 0.75|DEVICE: PASCAL Laser, Green Laser 1|DEVICE: PASCAL Laser, 70% Yellow Laser 0.75|DEVICE: PASCAL Laser, 70% Yellow Laser 1|DEVICE: PASCAL Laser, 40% Yellow Laser 0.75|DEVICE: PASCAL Laser, 40% Yellow Laser 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: End to End Anastomosis With Omega Suture Versus End to Anterior Rectal Wall In Colorectal Anastomosis in Sigmoid and Upper Rectal Cancer
Status: RECRUITING
Conditions: End to End Anastomosis|Colorectal Anastomosis|End to Anterior Rectal Wall|Sigmoid Cancer|Upper Rectal Cancer
Interventions: OTHER: End to end with Omega suture|OTHER: End to anterior rectal wall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study
Status: WITHDRAWN
Conditions: Stress Urinary Incontinence
Interventions: DRUG: Duloxetine|DRUG: Imipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intermittent Tiotropium in Early Childhood Wheezing
Status: COMPLETED
Conditions: Wheezy Bronchitis|Asthmatic Bronchitis|Wheezing|Obstruction Airway
Interventions: DRUG: Tiotropium Bromide|DRUG: Fluticasone Propionate|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Oral Energy Drinks Compared to Warming Matress on Body Temperature During Combined Spinal-epidural Anesthesia for Elective Cesarean Delivery.
Status: NOT_YET_RECRUITING
Conditions: Cesarean Section Complications
Interventions: OTHER: Oral energy drinks|DEVICE: Warming matress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of HIPEC in the Treatment of Locally Advanced Gastric Cancer After radIcal Gastrectomy With D2
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: D2 lymphadenectomy|PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Systemic chemotherapy (XELOX or SOX regimens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute,Leukemia, Lymphoid
Interventions: DRUG: Dasatinib|DRUG: prednisone|DRUG: cyclophosphamide|DRUG: daunorubicin|DRUG: vincristine|DRUG: cytarabine|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: dexamethasone|DRUG: mitoxantrone|DRUG: etoposide|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography
Status: TERMINATED
Conditions: Thyroid|Thyroid Cancer|Hypoparathyroidism|Vascularization
Interventions: DRUG: Indocyanine green|DEVICE: SPY Portable Handheld Imaging (SPY-PHI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
Status: UNKNOWN
Conditions: Cervical Cancer|Cervical Dysplasia|Human Papillomavirus Infection
Interventions: DIAGNOSTIC_TEST: Self-collected HPV vaginal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing Use Of Mifepristone After Progestin Priming For Use As "Missed Period Pills"
Status: UNKNOWN
Conditions: Missed Menstrual Period
Interventions: DRUG: Levonorgestrel|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paramedian Spinal Anaesthesia : Comparison Between Land-mark Guided Technique and Real-time Ultrasound Guided Technique.
Status: UNKNOWN
Conditions: Paramedian Spinal Anaesthesia|Real Time Ultrasound Guiding
Interventions: PROCEDURE: conventional paramedian spinal anesthesia|DEVICE: ultrasound guided paramedian spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: Mezigdomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas
Status: UNKNOWN
Conditions: Ewing Sarcoma|Rhabdomyosarcoma
Interventions: BIOLOGICAL: Expanded , Activated NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Iridoid Enriched Beverage on Skin Autofluorescence
Status: COMPLETED
Conditions: Oxidative Stress|Quality of Life|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: iridoid enriched mixed fruit beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Living Donor Liver Transplantation Under Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial
Status: COMPLETED
Conditions: Liver Cirrhosis(Who Will Undergo Planed Liver Transplantation)
Interventions: DRUG: inhalation (desflurane) group|DRUG: total intravenous (propofol) anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-Small Cell Lung Cancer Who Have Progressed on Prior Anti- Programmed Death-ligand 1 (PD-[L]1) Therapy and Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer, Non-Small Cell
Interventions: BIOLOGICAL: Cobolimab|BIOLOGICAL: Dostarlimab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Gantacurium Chloride for Injection in Tracheal Intubation in Healthy Adult Patients Undergoing Surgery Under General Anesthesia
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gantacurium Chloride for Injection (AV430A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of High-dose Melphalan HCL for Injection in MM Patients With Auto-HSC Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan Hydrochloride for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transcranial Direct Current Stimulation in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT