pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Dose Ranging Study of Delayed Release Beclomethasone for Prevention of Acute Enteritis in Patients With Rectal Cancer
Status: COMPLETED
Conditions: Enteritis
Interventions: DRUG: SGX201 (delayed release beclomethasone 17,21-dipropionate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Advance Directives Completion Rates and an Intervention to Address Health Literacy in a Clinic Population
Status: COMPLETED
Conditions: Health Literacy
Interventions: BEHAVIORAL: Advance Directives|BEHAVIORAL: Advance Directives without assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low-Intensity Focused Ultrasound for Treatment-Resistant Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DEVICE: Low-Intensity Focused Ultrasound Pulsation|DEVICE: Sham Low-Intensity Focused Ultrasound Pulsation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients.
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Chronic
Interventions: DRUG: 4-Aminopyridine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-recurrence Treatment of Postresection on HCC Patients With MVI Presence and Over-expression of ASPH
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient
Status: COMPLETED
Conditions: Argininosuccinate Synthetase Deficient
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RSA Study Using Two Types of Uncemented Acetabular Components and the Uncemented HA Coated Symax Stem
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Tritanium acetabular component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Online Training in Cardiopulmonary Resuscitation Maneuvers for a Network of Volunteers.
Status: NOT_YET_RECRUITING
Conditions: Cardiorespiratory Arrest|Cardiopulmonary Arrest With Successful Resuscitation
Interventions: OTHER: online CPR-AED training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Engaging and Capturing Undiagnosed Myasthenia Gravis Participants Through a Social Media Campaign Paired With a Self-moderated Assessment
Status: RECRUITING
Conditions: Myasthenia Gravis|Neuromuscular Manifestations|Neuromuscular Diseases
Interventions: BEHAVIORAL: Social media recruitment|BEHAVIORAL: Self-Assessment|BEHAVIORAL: Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population
Status: TERMINATED
Conditions: Heart Failure|Chronic Obstructive Pulmonary Disease|Cardiovascular Disease|Diabetes|Osteoporosis
Interventions: OTHER: Multidisciplinary team interventions|OTHER: Multidisciplinary team bimonthly visits either in person or via telephone.|OTHER: Usual case management and pharmacy management as provided by the health Plan and the pharmacy benefit manager
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
Status: RECRUITING
Conditions: Inferior Alveolar Nerve Injuries
Interventions: PROCEDURE: Traditional Extraction|PROCEDURE: Orthodontic Extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRECISE CURATE.AI Pilot Clinical Trial
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DEVICE: CURATE.AI|DRUG: Capecitabine|DRUG: XELOX|DRUG: XELIRI|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neck Dissection vs Radiotherapy for Cervical Metastases in Advanced Hypopharyngeal Cancer
Status: NOT_YET_RECRUITING
Conditions: Hypopharyngeal Carcinoma
Interventions: PROCEDURE: Neck dissection followed by radiotherapy(50Gy) according to risk factors|RADIATION: Definitive radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
Status: RECRUITING
Conditions: Laryngeal Nerve Injuries|Thyroidectomy|Voice Change
Interventions: DEVICE: Using Neuromonitoring to find EBSLN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Role of SURGical TElementoring in Acquisition of Surgical Skills of Laparoscopic Cholecystectomy. SURGTEACH Trial
Status: NOT_YET_RECRUITING
Conditions: Surgical Education|Surgical Telementoring
Interventions: DEVICE: Surgical telementoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Reflux Infant With Magnesium Alginate
Status: UNKNOWN
Conditions: Gastroesophageal Reflux|Regurgitation|Vomiting|Chronic Cough
Interventions: DRUG: Gastrotuss|DIETARY_SUPPLEMENT: thickened milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DHEA Against Vaginal Atrophy - 3-Month Efficacy Study
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: Placebo|DRUG: DHEA|DRUG: DHEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Pharmacokinetic Interactions in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Group 1: JW0104(Period 1), C2207(Period 2), JW0104 + C2207(Period 3)|DRUG: Group 2: JW0104 + C2207(Period 1), JW0104(Period 2), C2207(Period 3)|DRUG: Group 3: C2207(Period 1), JW0104 + C2207(Period 2), JW0104(Period 3)|DRUG: Group 4: JW0104(Period 1), JW0104 + C2207(Period 2), C2207(Period 3)|DRUG: Group 5: JW0104 + C2207(Period 1), C2207(Period 2), JW0104(Period 3)|DRUG: Group 6: C2207(Period 1), JW0104(Period 2), JW0104 + C2207(Period 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prenatal Antibiotics and Breast Milk / Neonatal IgA
Status: RECRUITING
Conditions: Prenatal Exposure Delayed Effects|Antibiotic Prophylaxis|Dysbiosis|Neonatal Infection|Breast Milk; Noxious Influence, Affecting Fetus
Interventions: DRUG: Antibiotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Dialysability and Safety of P03277 in Healthy Volunteers and in Patients With Impaired Renal Function
Status: COMPLETED
Conditions: Renal Insufficiency|Healthy Volunteers
Interventions: DRUG: P03277
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lingzhi and Sen Miao San for the Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Lingzhi and Sen Miao San
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bivalirudin in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary PCI
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Angiomax (bivalirudin) anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tau Positron Emission Tomography (PET) Longitudinal Substudy Associated With: Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers in the Treatment of Autosomal-Dominant Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Crenezumab|DRUG: Placebo|OTHER: [^18F]GTP1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Diuretic Effect With Furosemide Alone Versus the Combination of Furosemide and Albumin in Cirrhotic Patients
Status: TERMINATED
Conditions: Cirrhosis, Liver|Volume Overload|Fluid Overload
Interventions: DRUG: Furosemide Injection|DRUG: Albumin Human
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Bladder Cancer|Urothelial Carcinoma|Triple-negative Breast Cancer|Lung Cancer|Colorectal Cancer|Gastric Cancer|Ovarian Cancer|Pancreatic Cancer
Interventions: DRUG: Diagnostic Test: MNPR-101-DFO*-89Zr PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: SGLT2 inhibitor|DEVICE: Biosense Breath Ketone Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals
Status: UNKNOWN
Conditions: Analgesic Response
Interventions: DRUG: morphine sulfate|DRUG: hydrocodone|DRUG: hydromorphone HCI|DRUG: oxycodone|DRUG: buprenorphine|DRUG: oral tablet placebo|DRUG: sublingual tablet placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Subacromial Ozone (O2-O3) and Corticosteroid Injections in the Treatment of Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Rotator Cuff Tendinopathy
Interventions: PROCEDURE: Ozone (O2-O3) injection|PROCEDURE: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Imagery and Action Observation in Patients With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Exercise + motor imagery and action observation|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation and Mindfulness Patients With AUD
Status: RECRUITING
Conditions: Alcohol Dependence
Interventions: DEVICE: Transcutaneous vagus nerve stimulation|DEVICE: Closed-loop AM-tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assisted or Controlled Ventilation in Ards (Ascovent)
Status: UNKNOWN
Conditions: ARDS|Ventilator-Induced Lung Injury|Mechanical Ventilation Complication|Inflammatory Response
Interventions: DIAGNOSTIC_TEST: assessment of inflammatory response during PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Firibastat in Treatment-resistant Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Firibastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: H2 Haplotype and CYP3As Polymorphisms and the Antiplatelet Response to Clopidogrel
Status: COMPLETED
Conditions: Coronary Artery Disease|Elective Percutaneous Coronary Intervention
Interventions: DRUG: Clopidogrel|PROCEDURE: Blood sampling - platelet aggregation|PROCEDURE: Blood sampling - genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)
Status: RECRUITING
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Leukocyte and Platelet Rich Fibrin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Analgesia After Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Arthroplasty
Interventions: PROCEDURE: Continuous femoral nerve block + periarticular infiltration|PROCEDURE: Intraarticular and periarticular ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Conditions
Status: RECRUITING
Conditions: Mental Health Issue|Mental Health Disorder|Mental Health|Depression|Depression, Anxiety|Anxiety|Anxiety Disorders|Anxiety Depression|Anxiety State
Interventions: COMBINATION_PRODUCT: VIOME Precision Nutrition Program|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Pharmacokinetics of Telmisartan in Combination With Lacidipine in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan|DRUG: Lacidipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism
Status: UNKNOWN
Conditions: Hypersplenism
Interventions: DEVICE: Microwave Thermal Coagulation|DEVICE: Partial Splenic Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study)
Status: UNKNOWN
Conditions: Subcutaneous Emphysema
Interventions: DEVICE: SurgiQuest AirSeal Insufflation System (AIS)|DEVICE: Conventional Insufflation System (CIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Breast Cancers Treated by Neoadjuvant Therapy Via Diffusion-weighted Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Diffusion-weighted Nuclear Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study To Assess Efficacy And Safety Of Different Doses Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444 6.25|DRUG: GW642444 3mcg|DRUG: GW642444 12.5mcg|DRUG: GW642444 25mcg|DRUG: GW642444 50mcg|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Step by Step": A Feasibility Study of the Promotion of Lunchtime Walking to Increase Physical Activity and Improve Mental Well-being in Sedentary Employees
Status: UNKNOWN
Conditions: Exercise|Sedentary
Interventions: OTHER: 16-week lunchtime walking intervention|OTHER: delayed treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Vitamin D Fortification on Vitamin D Metabolite Profiles and Status in Vitamin D Insufficient Individuals
Status: WITHDRAWN
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Rooibos Iced-Tea (Control)|DIETARY_SUPPLEMENT: Rooibos Tea - Vitamin D3|DIETARY_SUPPLEMENT: Rooibos Tea- Vitamin D3 & Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KRT-232 and TKI Study in Chronic Myeloid Leukemia
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: KRT-232|DRUG: Dasatinib|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Safety and Efficacy of Meplazumab in Patients With COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Meplazumab for Injection|DRUG: Sterile normal saline (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects Of Percussion With Diaphragmatic Breathing Exercises On Airway Clearance In Elderly Pneumonia Patients
Status: RECRUITING
Conditions: Pneumonia
Interventions: OTHER: Percussions|OTHER: , Diaphragmatic breathing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Prescribing Trends and Associated Outcomes of Antiepileptic Drugs in US Nursing Homes Surrounding the COVID-19 Pandemic
Status: ENROLLING_BY_INVITATION
Conditions: Dementia
Interventions: OTHER: Pre-Extraction Phase|OTHER: Extraction Phase|OTHER: Post-Extraction Phase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer
Status: TERMINATED
Conditions: Prostate Adenocarcinoma|Stage IIA Prostate Cancer AJCC v7|Stage IIB Prostate Cancer AJCC v7
Interventions: DRUG: Goserelin Acetate|OTHER: Laboratory Biomarker Analysis|DRUG: Leuprolide Acetate|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: atorvastatin|DRUG: atorvastatin|DRUG: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib in Metastatic HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm|Antineoplastic Agents|Anlotinib
Interventions: DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immunogenicity and Safety of the Vaccination of Inactivated Enterovirus 71 Vaccine and Seasonal Influenza Vaccine
Status: COMPLETED
Conditions: Seasonal Influenza|Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: EV71 +SIV|BIOLOGICAL: EV71|BIOLOGICAL: SIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Short Course of Glucocorticoid in Patients With Diabetes Mellitus(DM) Type 2
Status: COMPLETED
Conditions: Diabetes|Hyperglycemia Steroid-induced
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BIOLOGICAL: Biostat® Disc Augmentation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects
Status: COMPLETED
Conditions: Spasmodic Torticollis
Interventions: DRUG: E2014 (Botulinum toxin type B)|DRUG: E2014 (Botulinum toxin type B) Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: INTENT Pilot Study - Enhancing Adherence Intentions to Endocrine Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|Breast Carcinoma
Interventions: BEHAVIORAL: Endocrine Therapy Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Sensors for the Detection of Cancer-Related Lymphedema, Project Limb Rescue Study
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Lymphedema|Malignant Solid Neoplasm
Interventions: PROCEDURE: Bioelectric Impedance Analysis|OTHER: Exercise|PROCEDURE: Photoplethysmography|BEHAVIORAL: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease
Status: RECRUITING
Conditions: Lung Diseases, Interstitial
Interventions: BIOLOGICAL: Belimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver Function
Status: COMPLETED
Conditions: Schizophrenia|Hepatic Impairment
Interventions: DRUG: Intermediate release (IR) Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Left and Right Radial Approach for Percutaneous Coronary Procedures
Status: COMPLETED
Conditions: Transradial Approach,|Coronary Angiography,|Percutaneous Coronary
Interventions: PROCEDURE: left radial approach|PROCEDURE: Right radial approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Induction and Adjuvant Camrelizumab Combined With Chemoradiation for LA-HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Concurrent cisplatin chemotherapy|RADIATION: Intensity-modulated radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Bicalutamide|DRUG: Buserelin|DRUG: Darolutamide|DRUG: Degarelix|DRUG: Flutamide|DRUG: Goserelin|DRUG: Histrelin|DRUG: Leuprolide|RADIATION: Radiation Therapy|DRUG: Relugolix|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemotherapy Based on Genetic Testing in Patients With High-Risk Salivary Gland Tumors
Status: COMPLETED
Conditions: Salivary Gland Tumors|Head and Neck Cancer
Interventions: DRUG: Docetaxel|RADIATION: Intensity-modulated radiotherapy|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vaniprevir (MK7009) Administered With Pegylated-Interferon and Ribavirin (MK-7009-007)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Comparator: Vaniprevir|DRUG: Comparator: Pegylated-Interferon (Peg-IFN)|DRUG: Comparator: Ribavirin|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|COPD|Emphysema|Chronic Bronchitis
Interventions: DRUG: Nebulized arformoterol|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: BIOLOGICAL: GSK208141|BIOLOGICAL: Havrix (investigational formulation)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: graft-versus-tumor induction therapy|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical or Peripheral Catheter Insertion for Preterm Infants on Admission to the NICU
Status: UNKNOWN
Conditions: Hypothermia, Newborn|Preterm Birth Complication|Neonatal Hypothermia
Interventions: PROCEDURE: Vascular access on admission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Skeletal Muscle Protein Synthetic Response to Amino Acid and Peptides
Status: COMPLETED
Conditions: Protein Metabolism
Interventions: BEHAVIORAL: Resistance Exercise|BEHAVIORAL: No Resistance Exercise|DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Dileucine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bortezomib and Flavopiridol in Treating Patients With Recurrent or Refractory Indolent B-Cell Neoplasms
Status: COMPLETED
Conditions: Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Nodal Marginal Zone Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Refractory Plasma Cell Myeloma|Splenic Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Bortezomib|DRUG: Alvocidib Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Filgrastim Followed By SCT in Patients With Chronic or Accelerated Phase Myelogenous Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: filgrastim|DRUG: recombinant interferon alfa|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation in COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: Transcranial direct-current stimulation|DEVICE: Transcranial direct-current stimulation|DEVICE: Sham Transcranial direct-current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitreous Levels of Cysteine-rich 61 in Patients With Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: intravitreal injection of 1.25 mg of bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Compare the Safety and Pharmacokinetics of SHR-1314 Injection in Healthy Subjects at Different Specifications Devices
Status: COMPLETED
Conditions: Moderate-to-Severe Plaque Psoriasis
Interventions: DRUG: SHR-1314|DRUG: SHR-1314
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Antihyperglycemic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Safety and Efficacy Study in Subjects With Overweight or Obese Class - I, to Evaluate the Degree of Significant Weight Loss by Regular Intake of Phaseolean (White Kidney Bean Standardized Extract)
Status: COMPLETED
Conditions: Body Weight in the Overweight and Obese Class - I Population
Interventions: OTHER: Phaseolean (White Kidney Bean Standardized Extract) 1500 mg Capsules|OTHER: Phaseolean (White Kidney Bean Standardized Extract)3000 mg Capsules|OTHER: Placebo (Resistant Dextrin) Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AZD2115 Single Ascending Dose Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Lung Disease Causing Persistent Narrowing of the Airways
Interventions: DRUG: AZD2115|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability of Idebenone in Boys With Cardiac Dysfunction Associated With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: idebenone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine Dorsolateral Prefrontal Cortex Behavioural Flexibility
Status: COMPLETED
Conditions: Cognitive Change
Interventions: DEVICE: Cathodal Transcranial direct current stimulation|DIETARY_SUPPLEMENT: L-Tyrosine|DEVICE: Transcranial direct current stimulation (sham)|DIETARY_SUPPLEMENT: Cellulose (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Aromatherapy on Neonatal Abstinence Syndrome and Salivary Cortisol Levels
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome|Aromatherapy
Interventions: DRUG: lavender and chamomile essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Blue Light Flexible Cystoscopy With Cysview in the Detection of Bladder Cancer in the Surveillance Setting
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Hexaminolevulinate hydrochloride|DEVICE: KARL STORZ D-Light C PDD Flexible Videoscope System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Silicone Oil Versus Gas in PDR Patients Undergoing Vitrectomy
Status: COMPLETED
Conditions: Diabetic Retinopathy|Retinal Detachment
Interventions: PROCEDURE: PPV/SO|PROCEDURE: PPV/C3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study: Evaluation of the Treatment of Striae Using Ultherapy® in Combination With Laser Treatment
Status: COMPLETED
Conditions: Scars|Striae
Interventions: DEVICE: Ultherapy® treatment only|DEVICE: Ultherapy® treatment and CO2 laser treatment|DEVICE: CO2 Laser treatment only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of White Noise and Swaddling on Pain, Heart Rate, and Oxygen Saturation in Term İnfants Undergoing Eye Examinations
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: White Noise|OTHER: Swaddling|OTHER: White Noise+Swaddling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (Sumatriptan Succinate / Naproxen Sodium) Tablet Followed by IMITREX® (Sumatriptan Succinate)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: TREXIMA™|DRUG: IMITREX® (4mg)|DRUG: IMITREX® (6mg)|DRUG: IMITREX Tablet 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery in a Pediatric Population
Interventions: DRUG: Caffeine citrate 10mg/kg|DRUG: 0.9% Sodium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MM-111 in Combination With Multiple Treatments in Patients With HER2 Positive Cancer
Status: COMPLETED
Conditions: HER-2 Gene Amplification
Interventions: DRUG: Cisplatin, Capecitabine, Trastuzumab and MM-111|DRUG: Lapatinib +/- Trastuzumab and MM-111|DRUG: Paclitaxel, Trastuzumab and MM-111|DRUG: Lapatinib, trastuzumab, paclitaxel, and MM-111|DRUG: Docetaxel, trastuzumab and MM-111
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Azacytidine Followed by GM-CSF in Patients With Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Azacytidine|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Technology-enabled Exercise Program in Firefighters With Shoulder Pain.
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: OTHER: Exercise Program plus Education|OTHER: Educational Program (EP).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Cost-effectiveness of Motion Style Acupuncture Treatment (MSAT) for Acute Neck Pain: A Multi-center Randomized Controlled Trial
Status: COMPLETED
Conditions: Acute Neck Pain
Interventions: OTHER: Motion Style Acupuncture Treatment (MSAT)|OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Redox Regulation in Patients With Relapsed or Refractory CD20+ NHL
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma (NHL)
Interventions: DRUG: Rituxan|DRUG: motexafin gadolinium|DRUG: 111Indium-Zevalin and 90Yttrium-Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Standard therapy|DRUG: Astaxanthin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Pathways Program Impact on Patient Shared Decision Making and Experience in Academic and Community Practice
Status: COMPLETED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Breast Carcinoma|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Breast Carcinoma
Interventions: OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: T-Regulatory Cells in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: ALS (Amyotrophic Lateral Sclerosis)
Interventions: BIOLOGICAL: Autologous T-regulatory lymphocytes|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Supplemental Oxygen on Memory Testing in Healthy Adult Volunteers
Status: RECRUITING
Conditions: Cognition
Interventions: DEVICE: Cross Over Assignment Supplemental Oxygen and Supplemental Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbon Dioxide Rebreathing During Exercise Assisted by Non-invasive Ventilation
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: BiPAP® Vision® ventilator（"Ventilator", "Philips Respironics™ BiPAP® Vision®" ）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Reducing Colistin Use on Colistin Resistance in Humans and Poultry in Indonesia
Status: NOT_YET_RECRUITING
Conditions: Colonization, Asymptomatic|Colistin|Mcr-1|Antimicrobial Resistance
Interventions: OTHER: screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ibandronate Versus Placebo in the Prevention of Bone Loss After Renal Transplantation.
Status: UNKNOWN
Conditions: Renal Transplant
Interventions: DRUG: Placebo|DRUG: Ibandronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)
Status: COMPLETED
Conditions: Myositis|Dermatomyositis|Polymyositis|Juvenile Dermatomyositis
Interventions: DRUG: Rituximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0148-0000-0287 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin 287|DRUG: insulin glargine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule Formulations
Status: COMPLETED
Conditions: Pharmacokinetic Assessments in Healthy Volunteers
Interventions: DRUG: PPI-668 capsule|DRUG: PPI-668 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Adaptive Servoventilation (ASV) in Patients With Central Sleep Apnea Due to Chronic Opioid Use
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Central Sleep Apnea (Diagnosis)|Chronic Opioid Use
Interventions: DEVICE: Adaptive servo-ventilation (ASV)|DEVICE: Bi-Level PAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide Treatment On Coronary Progression
Status: COMPLETED
Conditions: Type 2 Diabetes|Coronary Artery Disease
Interventions: DRUG: Semaglutide 2 MG/1.5 ML Subcutaneous Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Youth With ADHD and Anxiety
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Anxiety, Separation|Social Phobia|Generalized Anxiety Disorder
Interventions: DRUG: methylphenidate|DRUG: fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lesion Preparation in Femoropopliteal Artery Occlusion Disease
Status: RECRUITING
Conditions: Femoropopliteal Artery Occlusion|Atherosclerosis Obliterans|Lesion; Vascular|In-stent Restenosis
Interventions: DEVICE: lesion preparation devices|DEVICE: conventional balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Safety and Effectiveness of Epoetin Alfa Versus Placebo in Patients With Persistent Anemia Caused by Advanced Cancer
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Use of tDCS in the Orofacial Pain
Status: RECRUITING
Conditions: Orofacial Pain
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocolytics Trial: Intravenous (IV) Magnesium Versus Oral Nifedpine in Fetal Fibronectin (FFN) Postive Population
Status: TERMINATED
Conditions: Labor, Premature
Interventions: DRUG: Magnesium|DRUG: Nifedlipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Safety Of CE 224,545 And Methotrexate In Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CE-224,535|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating a PDE5 Inhibitor for Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: Avanafil 100 mg|DRUG: Avanafil 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide During Cardiopulmonary Bypass in Neonates to Reduce Risk of Acute Kidney Injury
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Congenital Heart Disease
Interventions: DRUG: gases Nitric Oxide (gNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess PXL770 in Subjects With Adrenomyeloneuropathy (AMN) Form of X-linked Adrenoleukodystrophy (X-ALD or ALD)
Status: NOT_YET_RECRUITING
Conditions: Adrenomyeloneuropathy
Interventions: DRUG: PXL770
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pending Failure in Hard-hard Total Hip Arthroplasty
Status: COMPLETED
Conditions: Infection and Inflammatory Reaction
Interventions: OTHER: Metal ions dosage and evaluation of local/systemic reaction|OTHER: Noise registration and metal ions determination|OTHER: Metal ions dosage, evaluation of local/systemic reaction, noise registration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
Status: COMPLETED
Conditions: Insulin Resistance|Obesity|Diabetes|Hypertension|Dyslipidemias|Metabolic Syndrome
Interventions: BEHAVIORAL: Diet Counseling|BEHAVIORAL: Exercise Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT