pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention
Status: RECRUITING
Conditions: Polysubstance Addiction|Opioid Medication Assisted Treatment|Treatment Adherence|Retention in Care|Substance-Related Disorders
Interventions: BEHAVIORAL: Peer-Delivered Behavioral Activation ("Peer Activate")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Stellate Ganglion Block in Traumatic Brain Injury Patients
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Stellate ganglion block|PROCEDURE: Placebo block|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTIMAS: OPtimal TIMing of Anticoagulation After Acute Ischaemic Stroke : a Randomised Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Acute|Atrial Fibrillation
Interventions: DRUG: Direct oral anticoagulant (DOAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer
Status: COMPLETED
Conditions: Radiation-Induced Xerostomia|Head and Neck Cancer|Radiation Toxicity|Oral Complications of Chemotherapy and Head/Neck Radiation
Interventions: OTHER: Standard Oral Hygiene|OTHER: Standard Oral Hygiene + True Acupuncture|OTHER: Standard Oral Hygiene + Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery
Status: UNKNOWN
Conditions: Oropharyngeal Neoplasms
Interventions: DEVICE: Peri-Neuronal Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Effect of Adrenaline and Without Adrenaline in Tumescent Solutions on Bleeding Control of Skin Graft Donor Site.
Status: COMPLETED
Conditions: Bleeding Time
Interventions: OTHER: tumescent with adrenaline|OTHER: tumescent without adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Safety, Tolerability and Preliminary Pharmacokinetics of BILR 355 BS Single-rising Dose Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BILR 355 BS|DRUG: PEG 400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patients
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: 10 mg ilaprazole|DRUG: 15 mg ilaprazole|DRUG: 40 mg esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Type 1 Diabetes Aerobic and Resistance Exercise (T1-DARE)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Resistance and/or Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-Enhanced Ultrasound for Kidney Cancer Subtyping and Staging
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: Perflutren lipid microsphere|DRUG: Sulfur hexafluoride lipid microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of a New Investigational Medicinal Product to Treat Patients With Advanced or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: W0101 - Cohort A1|DRUG: W0101 - Cohort A2|DRUG: W0101 - Expansion Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Collaborative Theory-based Intervention to Promote Physical Activity Among Sedentary Parents and Their Children
Status: RECRUITING
Conditions: Inactivity/Low Levels of Exercise|Inactivity, Physical
Interventions: BEHAVIORAL: Integrated Behaviour Change Based Intervention Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine and the Inflammatory Response in Pediatric Cardiac Surgery
Status: UNKNOWN
Conditions: Cardiac Surgical Procedures
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pre-Warming of Local Anesthesia in Reducing Pain Perception During Injection in Children
Status: COMPLETED
Conditions: Local Anesthesia|Dental Anesthesia
Interventions: OTHER: Local anesthesia solution at room temperature|OTHER: Local anesthesia solution pre-warmed to 37°C|OTHER: Local anesthesia solution pre-warmed to 40°C|OTHER: Maxillary infiltration technique|OTHER: Inferior alveolar nerve block technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate MRI Guided Biopsy Compared With Transrectal Ultrasound Guided Biopsy of the Prostate in Men With Increased PSA Values
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: MRI guided prostate biopsy and TRUS guided biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S0232 Dexamethasone With or Without Lenalidomide in Treating Patients With Previously Untreated Stage I, Stage II, or Stage III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: lenalidomide|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Intervention for Asthmatic and Allergic Patients
Status: UNKNOWN
Conditions: Asthma|Allergy
Interventions: BEHAVIORAL: Virtual educational intervention|BEHAVIORAL: Written educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation to Compare Safety and Efficacy of DAISE and Stent Retrievers for Thrombectomy In Acute Ischemic Stroke Patients
Status: WITHDRAWN
Conditions: Stroke|Stroke, Ischemic|Stroke, Acute|Cerebrovascular Disorders|Cerebrovascular Accident
Interventions: DEVICE: DAISe Device|DEVICE: Trevo or Solitaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed and/or Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20
Status: WITHDRAWN
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: BIOLOGICAL: Corticosteroids & tanCART19/20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of GLN Dipeptide in the SICU
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Glutamine dipeptide with 15% Clinisol|DRUG: 15% Clinisol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thromboelastography (TEG) and Clopidogrel Withdrawal Time in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Hip Fracture
Interventions: PROCEDURE: Thrombelastograph and surgical timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of NBP608 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Varicella Zoster|Immunization; Infection
Interventions: BIOLOGICAL: VARIVAX|BIOLOGICAL: ZOSTAVAX|BIOLOGICAL: NBP6081|BIOLOGICAL: NBP6082|BIOLOGICAL: NBP6083
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Assessment of Usage of Cleft Margin Flap With Anterior Palatal Closure in Closure of Naso-alveolar Defect.
Status: UNKNOWN
Conditions: Nasoalveolar Fistula (Defect)
Interventions: PROCEDURE: usage of cleft margin flap with anterior palatal closure during primary cleft lip repair.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ImmunoTEP for Patients With Medullary Thyroid Carcinoma.
Status: COMPLETED
Conditions: Medullary Thyroid Carcinoma
Interventions: DRUG: • TF2 and 68 Ga-IMP-288
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of VBY-891 in Healthy Volunteers After Single or Multiple (7 Days) of Oral Dosing (VBY891P1)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: VBY-891|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stories for Change: Digital Storytelling for Diabetes Self-Management Among Hispanic Adults
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: Digital Storytelling Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: cytisinicline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study
Status: RECRUITING
Conditions: Chromophobe Renal Cell Carcinoma|Clear Cell Papillary Renal Tumor|Clear Cell Renal Cell Carcinoma|Kidney Oncocytoma|Papillary Renal Cell Carcinoma|Urothelial Carcinoma
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iCare 2: Personalized Genomic Mutation Informed Treatment of Patients With Myelodysplastic Syndromes
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: FDA-approved drug or combination of drugs|DRUG: FLAG induction|DRUG: 7 + 3 induction|DRUG: Low-dose cytarabine|OTHER: Supportive care alone|DEVICE: Computational biology simulations software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of BI 691751 Administered With and Without Food to Healthy Male Subjects
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: BI 691751 fasted|DRUG: BI 691751 after high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes, Type 2
Interventions: DRUG: Placebo|DRUG: 150 mg PF-04991532|DRUG: 450 mg PF-04991532|DRUG: 750 mg PF-04991532|DRUG: Sitagliptin 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Efficacy and Safety of Hetrombopag in the Preoperative Patients of Thrombocytopenia
Status: RECRUITING
Conditions: Thrombocytopenia
Interventions: DRUG: Hetrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)
Status: COMPLETED
Conditions: Hypophosphatasia
Interventions: DRUG: Asfotase Alfa (ALXN1215)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of a Booster Vaccination With a Recombinant H5N1 Influenza HA Vaccine in Primed Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Recombinant Influenza HA Vaccine (H5N1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Point-of-Care Video Prescriptions to Improve Aftercare Following Discharge From a Pediatric Emergency Department
Status: UNKNOWN
Conditions: Compliance|Emergency Department Aftercare|Emergency Department Utilization
Interventions: OTHER: Video Prescription (additional education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery
Status: RECRUITING
Conditions: Elderly Patients|Malnutrition|Hip Fractures|Nutritional Intervention|Perioperative Outcomes|Survival
Interventions: DIETARY_SUPPLEMENT: Nutritional intervention group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Functional Performance of Voluntary Opening and Closing Body Powered Prostheses
Status: COMPLETED
Conditions: Upper Limb Amputation
Interventions: DEVICE: Hosmer 5XA voluntary opening hook|DEVICE: TRS Grip 3 voluntary closing hook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Socket Preservation Using Autogenous Bone Graft Versus MPM
Status: UNKNOWN
Conditions: Bone Graft; Complications
Interventions: OTHER: MPM(Mineralized plasmatic matrix).|OTHER: Autogenous Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urban Zen Integrative Therapy for Persons With Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension|Chronic Disease
Interventions: BEHAVIORAL: Urban Zen Integrative Therapy (UZIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases
Status: COMPLETED
Conditions: Breast Cancer|Hypercalcemia of Malignancy|Metastatic Cancer|Pain
Interventions: BIOLOGICAL: monoclonal antibody CAL|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assess the Safety and Efficacy of Nephoxil® in Subjects With End Stage Renal Disease (ESRD) on Dialysis
Status: COMPLETED
Conditions: Kidney Failure, Chronic|End-stage Renal Disease|Phosphorus Metabolism Disorders|Hyperphosphatemia
Interventions: DRUG: Ferric Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single Ascending Dose Study of Safety and Tolerability of SPH3127 Tablet in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: SPH3127
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Incision Versus Three Port Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DEVICE: Single incision laparoscopic cholecystectomy|DEVICE: Three port laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-Guided Pancreatic Injection of Cyst (EPIC) Trial
Status: COMPLETED
Conditions: Pancreatic Cystadenoma
Interventions: PROCEDURE: Ethanol injection into a cyst
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
Status: TERMINATED
Conditions: Effects of; Anesthesia, in Labor and Delivery|Pregnancy|Prolonged First Stage of Labor
Interventions: PROCEDURE: Epidural de novo|PROCEDURE: CSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PK/PD Study of Multiple Dose of SHR3824 in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: SHR3824|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Anesthesia Block in Fibula Free Flap Reconstruction
Status: WITHDRAWN
Conditions: Anesthesia, Local|Surgery|Opioid Use|Pain, Postoperative|Head and Neck Neoplasms
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 68Ga-DOTATATE PET Scan Imaging in Patients With Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Neuroendocrine|Neuroendocrine Tumor|Neuroendocrine Cancer|Neuroendocrine Carcinoma|Carcinoid|Carcinoid Tumor|Islet Cell Tumor|Apudoma
Interventions: DRUG: 68Ga-DOTATATE will be given in tracer doses and injected intravenously to image tumors by Positron Emission Tomography.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Masticatory Muscle Activity in Pediatric Patients Undergoing Rapid Maxillary Expansion
Status: ENROLLING_BY_INVITATION
Conditions: Maxillar Hypoplasia
Interventions: DEVICE: Electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Activity of SRX246 in Adults With Intermittent Explosive Disorder
Status: COMPLETED
Conditions: Intermittent Explosive Disorder
Interventions: DRUG: SRX246|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Vaccine Uptake in Underresourced Public Housing Areas
Status: COMPLETED
Conditions: Coronavirus|Vaccine Refusal
Interventions: BEHAVIORAL: Increasing Willingness and Uptake of COVID-19 Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Acupuncture and Moxibustion Treatment in Patients With Quiescent Crohn's Disease:Evaluation With fMRI
Status: COMPLETED
Conditions: Crohn's Disease|CAM
Interventions: OTHER: electroacupuncture|OTHER: moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Static Magnetic Field on Dental Implant Stability.
Status: RECRUITING
Conditions: Implant Site Reaction
Interventions: OTHER: Magnet disc|OTHER: Stainless steel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in Severe Premenstrual Syndrome
Status: UNKNOWN
Conditions: Premenstrual Syndrome
Interventions: DRUG: Combined oral contraceptives|DRUG: Fluoxetine|DRUG: Combined oral contraceptives placebo|DRUG: Fluoxetine placebo|PROCEDURE: Daily record of severity of problems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Following Glide Path Preparation Using Rotary Neoniti GPS File and Manual K-files
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Rotary Neoniti GPS file|OTHER: Manual stainless steel K-files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Revlimid, Endoxan, Prednison Evaluation After Prior Revlimid Treatment (REPEAT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide, endoxan, prednisone|DRUG: lenalidomide, endoxan, prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures
Status: COMPLETED
Conditions: Low Back Pain|Degeneration of Lumbosacral Intervertebral Disc|Muscle Weakness|Spine Stiffness
Interventions: OTHER: SMT for low back pain patients|OTHER: Pain induction (optional)|OTHER: Low back pain participants without SMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nephronic Reduction After Neonatal Acute Renal Failure in Preterm
Status: COMPLETED
Conditions: Neonatal Acute Renal Failure in Preterm
Interventions: OTHER: renal echography|OTHER: Blood sampling|OTHER: collection of an urine sample|OTHER: Blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis
Status: COMPLETED
Conditions: Hypogonadism|Paraplegia|Bone Density|Osteoporosis
Interventions: DRUG: Testosterone Undeconate (Nebido-R, BAY86-5037)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequential Regimen of Bendamustine Followed by Obinutuzumab (GA101), Zanubrutinib (BGB-3111) and Venetoclax (ABT-199) in Patients With Relapsed/Refractory CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphoid Leukemia
Interventions: DRUG: Bendamustine|BIOLOGICAL: Obinutuzumab|BIOLOGICAL: Zanubrutinib|BIOLOGICAL: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum
Status: COMPLETED
Conditions: Left Ventricular Dysfunction|Cardiac Conduction Defect|Heart Failure|Sick Sinus Syndrome
Interventions: DEVICE: Left ventricular septum pacing lead
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison Between BMS-690514 and Erlotinib in Patients Who Were Previously Treated for NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: BMS-690514|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag in Myelodysplastic Syndrome (MDS) Patients With Thrombocytopenia
Status: TERMINATED
Conditions: Myelodysplastic Syndrome (MDS)|Thrombocytopenia
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GFM-Acadesine: A Phase I-II Trial of Acadesine
Status: TERMINATED
Conditions: SMD
Interventions: DRUG: ACADESINE 140mg/kg/d|DRUG: ACADESINE 210mg/kg/d|DRUG: ACADESINE 315mg/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occult HCV Infection After DAAD Treatment in Haemodialysis Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DIAGNOSTIC_TEST: presence of HCV RNA in peripheral blood mononuclear cells (PBMCs) .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Study to Investigate the Safety and Tolerance of Therapeutic BCG in Postoperative Adjuvant Therapy in Subjects With Moderate to High-risk Non-muscular Invasive Bladder Cancer (NMIBC)
Status: COMPLETED
Conditions: Non-muscular Invasive Bladder Cancer
Interventions: DRUG: BCG for Therapeutic Use
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Campath for Induction and Maintenance Therapy in Pancreas After Kidney Transplantation
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: Tacrolimus|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Prolonged Exposure and Pramipexole for Posttraumatic Stress Disorder and Depression
Status: TERMINATED
Conditions: PTSD|MDD
Interventions: COMBINATION_PRODUCT: PE/Pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide 360ug|DRUG: Budesonide 720ug|DRUG: Budesonide 1440ug|DRUG: Budesonide720ug 4 times|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Double-blind Placebo Controlled Trial of Sentra PM, a Medical Food
Status: COMPLETED
Conditions: Sleep Disorder
Interventions: DRUG: Trazodone|OTHER: Sentra PM|DRUG: Sentra PM and Trazodone (CoPack Kit Trazamine)|DRUG: Placebo trazodone and placebo Sentra PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balance Acceptance and Commitment Therapy for Long COVID
Status: NOT_YET_RECRUITING
Conditions: Post-COVID-19 Syndrome|Long COVID
Interventions: BEHAVIORAL: Balance Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exclusive Intraoperative Radiation Therapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Toxicity
Interventions: RADIATION: 21 Gy radiation|RADIATION: 18 Gy radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXPAREL Post-tonsillectomy Clinical Trial
Status: UNKNOWN
Conditions: Tonsillectomy
Interventions: DRUG: Adjunct Exparel (bupivacaine liposome suspension 1.3%)|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unmodulated 5 Kilohertz Currents Versus TENS: Effect on Pain Thresholds, Tactile Threshold, and Nerve Conduction
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: 5 KHz|DEVICE: TENS|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy
Status: COMPLETED
Conditions: IGA Nephropathy
Interventions: DRUG: Fostamatinib 150 mg|DRUG: Fostamatinib 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).
Status: COMPLETED
Conditions: Giant Cell Arteritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery
Status: COMPLETED
Conditions: Morphine
Interventions: DRUG: 1 mg morphine soak in epidural oxidized cellulose|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Treatments, Including Neural Mobilization and Hip/Back Stretches for People Between 50-89 With Lumbar Spinal Stenosis and Leg Pain Provoked by Walking
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: Physical therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc in Potatoes Study
Status: COMPLETED
Conditions: No Conditions
Interventions: OTHER: Unfortified potato plus placebo|OTHER: Zinc Biofortified potato plus placebo|OTHER: Unfortified potato plus zinc supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: I Am Able: Population Based Rehabilitation in a Family Health Team
Status: COMPLETED
Conditions: Chronic Conditions|Arthritis|Diabetes|Hypertension|Chronic Pain
Interventions: BEHAVIORAL: Physiotherapy|BEHAVIORAL: Occupational Therapy|BEHAVIORAL: Capacity Building
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?
Status: UNKNOWN
Conditions: Propionibacterium
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Airway Pressure Release Ventilation for Moderate-to-severe Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: Low tidal volume ventilation|DEVICE: Airway pressure release ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on the Fecal Resistome During Helicobacter Pylori Eradication Therapy
Status: COMPLETED
Conditions: Gut Resistome
Interventions: DRUG: Saccharomyces Boulardii-Containing Product in Oral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Lavender Essential Oil On Birth Pain
Status: COMPLETED
Conditions: Labor Pain|Aromatherapy
Interventions: OTHER: Aromatherapy application /massage with lavender oil|OTHER: Aromatherapy application / inhalation with lavender oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging
Status: COMPLETED
Conditions: Stage IIB Lung Non-Small Cell Carcinoma AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Computed Tomography|RADIATION: Fludeoxyglucose F-18|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|PROCEDURE: Single Photon Emission Computed Tomography|RADIATION: Technetium Tc-99m Albumin Aggregated|RADIATION: Technetium Tc-99m Sulfur Colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Will Investigate How Food and Age Effect the Way the Body Handles the AZD5069 Drug Given as a Oral Dose
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD5069
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia
Status: COMPLETED
Conditions: Myopia|Myopic Astigmatism|Crosslinking|Corneal Ectasia|Myopic Regression
Interventions: PROCEDURE: LasikXtra|PROCEDURE: LASIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Melatonin Administration and Delirium Prevention in Patients Undergoing Vascular and Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: OTHER: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Two Universal Programs for Parents of Teenagers
Status: COMPLETED
Conditions: Mental Health Issue|Mental Disorder|Adolescent Behavior|Adolescent Development|Parent-Child Relations|Parenting
Interventions: BEHAVIORAL: ABC-teen|BEHAVIORAL: ParentWeb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Cerebral Glucose Metabolism in Healthy Volunteers Using 18 F-FDG PET: Evaluation of the Effects of Aging, Comparative Evaluation of Neurodegenerative and Psychiatric Pathologies.
Status: COMPLETED
Conditions: Neuro-Degenerative Disease
Interventions: DIAGNOSTIC_TEST: Diagnostic accuracy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study of MRI Imaging on Parotid Gland Stimulation
Status: UNKNOWN
Conditions: Parotid Neoplasms
Interventions: DEVICE: MRI|OTHER: Citric acid|OTHER: Gadovist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Defect
Interventions: PROCEDURE: Soft tissue flap + Connective Tissue Graft|DEVICE: Soft tissue flap + Geistlich Fibro-Gide®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Icotinib|DRUG: Befotertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parecoxib Versus Celecoxib Versus Oxycodone in Pain Control for Transcatheter Chemoembolization Procedure
Status: COMPLETED
Conditions: Liver Cancer|Pain Postoperative
Interventions: DRUG: Celecoxib 200mg oral capsule|DRUG: parecoxib sodium|DRUG: controlled-release oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dual-Task Zumba Gold for Improving the Cognition of Older Adults With MCI
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Dual-Task Zumba Gold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Whole-Person-Care Guide in Patients Receiving Care for Cancer or Complications From Cancer Treatment
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Infection|Malnutrition|Musculoskeletal Complications|Neutropenia|Radiation Toxicity|Thrombocytopenia|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: informational intervention|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy
Status: TERMINATED
Conditions: Advanced Adult Hepatocellular Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXCEL: Change in Cardiometabolic Disease Risk Factors During an Interactive Fitness Program
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: BEHAVIORAL: EXCEL|BEHAVIORAL: EXCEL|BEHAVIORAL: Nutrition Education ONLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Different Types of General Anesthesia on Postoperative Pupillary Reactivity
Status: RECRUITING
Conditions: Pupillary Reflex Impaired
Interventions: DIAGNOSTIC_TEST: PLR|DIAGNOSTIC_TEST: Alertness testing|PROCEDURE: Propofol anesthesia|PROCEDURE: Sevoflurane anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, PK and PD of Biosimilar Drug Ritumax® Compared to Original Drug MabThera®
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MabThera®|DRUG: Ritumax®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy With or Without AE-941 in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Adenosquamous Cell Lung Cancer|Large Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DRUG: shark cartilage extract AE-941|OTHER: placebo|DRUG: cisplatin|DRUG: vinorelbine tartrate|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility and Advantages of Subxiphoid Uniportal Video-assisted Thoracoscopic Surgery in Pulmonary Lobectomy
Status: UNKNOWN
Conditions: Lobectomy|Subxiphoid Uniportal Video-assisted Thoracoscopic Surgery
Interventions: PROCEDURE: Subxiphoid uniportal VATS|PROCEDURE: Three-port VATS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Group ACYW135 Meningococcal Polysaccharide Vaccine 002
Status: COMPLETED
Conditions: Meningitis
Interventions: BIOLOGICAL: Group ACYW135 Meningococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systane® Hydration PF and Systane® Hydration Preserved
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye
Interventions: OTHER: Polyethylene glycol 400 and propylene glycol solution/drops - Preservative Free (PF)|OTHER: Polyethylene glycol 400 and propylene glycol solution/drops - Preserved
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Effectiveness of Rasagiline Mesylate in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: rasagiline mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Acupuncture Treatment for Negative Symptoms of Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: acupuncture|DRUG: Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD, Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Active HEPA Air Cleaner|BEHAVIORAL: Motivational interviewing|DEVICE: Sham Air Cleaner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study Of Palbociclib (PD-0332991) In Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: palbociclib|DRUG: palbociclib|DRUG: palbociclib|DRUG: palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery
Status: COMPLETED
Conditions: Intraoperative Ureter Injury
Interventions: DRUG: Nerindocianine for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Neoplasms
Interventions: DEVICE: cannula ileostomy|DEVICE: loop ileostomy|DEVICE: LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Brain Polypeptide Solution in Mild Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: brain polypeptide solution|OTHER: same package of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Jacobson's Progressive Muscular Relaxation Technique in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Jacobson's progressive muscular relaxation technique|OTHER: 30 min walk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Alternative RUTF on Intestinal Permeability in Children With Severe Acute Malnutrition
Status: COMPLETED
Conditions: Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: S-RUTF|DIETARY_SUPPLEMENT: oat RUTF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Two Modalities of Prophylactic Nutritional Support During Treatment for Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Neoplasms
Interventions: PROCEDURE: percutaneous endoscopic gastrostomy tube placement|PROCEDURE: nasogastric tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)
Status: RECRUITING
Conditions: Glioblastoma, Adult
Interventions: DRUG: Pembrolizumab at 7 days prior|DRUG: Pembrolizumab at 14 days post|DRUG: Pembrolizumab at 35 days post|PROCEDURE: Laser Interstitial Thermotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of Intravitreal Mesenchymal Stem Cells for Acute Non Arteritic Anterior Ischemic Optic Neuropathy
Status: UNKNOWN
Conditions: Non Arteritic Ischemic Optic Neuropathy
Interventions: PROCEDURE: intravitreal injection of MSV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT