pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Status: TERMINATED
Conditions: Pain, Postoperative|Post-Mastectomy Chronic Pain Syndrome|Opioid Use
Interventions: PROCEDURE: Pectoralis Blockade (PECs)|PROCEDURE: Paravertebral Blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Phase 1 Study Evaluating the Safety and Pharmacokinetics of an Inhaled COVID-19 Inhibitor Delcetravir in Healthy Subjects
Status: UNKNOWN
Conditions: COVID-19
Interventions: COMBINATION_PRODUCT: Delcetravir dry powder inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Methotrexate|DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Relationship Between Functional Exercise Capacity, Respiratory Muscle Strength, Trunk Control, Balance and Activities of Daily Living in Individuals With Cerebral Palsi
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: TCMS, PEDİ, respiration, GMFCS,PBS,functional capacity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selenium as a Potential Treatment for Moderately-ill, Severely-ill, and Critically-ill COVID-19 Patients.
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Selenium (as Selenious Acid)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Management of Knee Septic Arthritis
Status: TERMINATED
Conditions: Septic Arthritis
Interventions: PROCEDURE: Arthroscopic Irrigation and Debridement|PROCEDURE: Open Arthrotomy with irrigation and debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar
Status: UNKNOWN
Conditions: Stem Cell Media|Hypertrophic Scar|Regeneration
Interventions: PROCEDURE: human stem cell conditioned media was applied after non-ablative laser therapy|PROCEDURE: normal saline was applied after non ablative laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunopathology of Polymyalgia Rheumatica on Shoulder Bursae's Biopsies
Status: COMPLETED
Conditions: Polymyalgia Rheumatica
Interventions: PROCEDURE: Synovial membrane biopsy with puncture of synovial fluid|PROCEDURE: Joint fluid sampling|PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study)
Status: NOT_YET_RECRUITING
Conditions: Pleural Mesothelioma
Interventions: DRUG: Carboplatin/Cisplatin - Pemetrexed - Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the Origin of Sperm Affect Embryo Ploidy in Patients With Severe Male Factor Infertility?
Status: RECRUITING
Conditions: Male Infertility
Interventions: PROCEDURE: Testicular sperm extraction (TESE)|OTHER: Ejaculate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders
Status: UNKNOWN
Conditions: Sleep Disorders, Circadian Rhythm
Interventions: DRUG: Melatonin|DRUG: Methylxanthine|PROCEDURE: Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of BMS-986177 in Participants With End-stage Renal Dysfunction on Chronic Stable Hemodialysis Treatment
Status: COMPLETED
Conditions: Thrombosis|Factor XI|Renal Impairment|ESRD (End-Stage Renal Disease)
Interventions: DRUG: BMS-986177
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Risk Reduction
Interventions: DEVICE: UTRA|BEHAVIORAL: UTRA feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Twice Daily Versus Twice Weekly Soak-and-Seal Baths in Pediatric Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BEHAVIORAL: Infrequent versus Frequent Soaking Baths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of a Medical Device "Device for Non-invasive Electromagnetic Therapy "TOR" in the Treatment of COVID-19"
Status: COMPLETED
Conditions: Coronavirus Infection COVID-19
Interventions: DEVICE: Exposure to "TOR" device|DEVICE: Exposure to switched off "TOR" device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Post-Training Supports for Health Workers in Benin
Status: COMPLETED
Conditions: Malaria|Pneumonia|Diarrhea|Measles|Malnutrition
Interventions: BEHAVIORAL: Health worker supports (supervision, job aids, incentives)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness Of Modified Chest PT Technidue In Pre And Post-Operative Program In Patients Open Heart Surgery
Status: UNKNOWN
Conditions: Pulmonary Complications
Interventions: DEVICE: BreatheMAX®|OTHER: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of DMR Using the Revita® in Subjects With Inadequately Controlled Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DEVICE: Duodenal Mucosal Resurfacing (DMR)|DEVICE: Duodenal Mucosal Resurfacing (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CC-42344 Safety Study in Healthy Participants
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: CC-42344|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children
Status: UNKNOWN
Conditions: Stridor
Interventions: DRUG: Budesonide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Placebo|DRUG: Golimumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Listening to Mom 2: Neural, Clinical and Language Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Birth
Interventions: BEHAVIORAL: Language Treatment|BEHAVIORAL: Control Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intralymphatic Immunotherapy in Increasing Doses, Substudy
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: ALK Diluent|DRUG: ALK Alutard SQ 5-grasses or ALK Alutard Birch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Incentives to Increase Mobility
Status: COMPLETED
Conditions: Pneumonia|Diabetes|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Social Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Tranexamic Acid in Reducing Blood Loss During and After Caesarean Section
Status: UNKNOWN
Conditions: Hemorrhage of Cesarean Section and/or Perineal Wound
Interventions: DRUG: Tranexamic Acid|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects on Small Airways of Two Long-term Extrafine Treatments in Asthma
Status: COMPLETED
Conditions: Bronchial Asthma
Interventions: DRUG: Salmeterol Fluticasone|DRUG: formoterol - beclometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open vs Laparoscopic Liver Surgery for Colorectal Liver Metastases
Status: COMPLETED
Conditions: Colorectal Liver Metastasis|Laparoscopic Liver Resection
Interventions: PROCEDURE: Liver resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension (PH)
Status: UNKNOWN
Conditions: Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Patients Colonized With Methicillin-Resistant Staphylococcus Aureus Prior to Bone and Joint Surgery
Status: WITHDRAWN
Conditions: Orthopedic Procedures|Methicillin-resistant Staphylococcus Aureus
Interventions: DRUG: Placebo|DRUG: Altabax (retapamulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Disease Management in Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: type1diabetes|Adolescent Behavior|Self Efficacy
Interventions: BEHAVIORAL: Adaptation to Adolescence and Type 1 Diabetes Management Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Glucagon Nasal Powder|DRUG: Glucagon Hydrochloride Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Immunogenicity and Safety of COVID-19 Vaccine (Produced in Beijing) in Patients With Hypertension and/or Diabetes
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: BIOLOGICAL: COVAX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Non-COVID-19 Acute Respiratory Distress Syndrome
Status: WITHDRAWN
Conditions: Acute Respiratory Distress Syndrome|Ards
Interventions: BIOLOGICAL: COVI-MSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Transcranial dIrect Current stiMulation (tDCS) in Progressive Supranuclear Palsy (PSP) (STIM-PSP)
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Motor and Cognitive Symptoms
Interventions: DEVICE: Anodal transcranial direct current stimulation (a-tDCS)|DEVICE: Sham Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of the ExPEC4V Clinical Trial Material After a Single Intramuscular Dose and a Second Dose 6 Months Later in Healthy Participants Aged 18 Years and Older
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ExPEC4V|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Fibromyalgia Education on Smart Phone Addiction, Pain, and Quality of Life
Status: COMPLETED
Conditions: Fibromyalgia|Pain Syndrome|Quality of Life|Addiction, Mobile Phone
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Proof of Principle Study of Pembrolizumab With SBRT in TKI mRCC Patients
Status: COMPLETED
Conditions: Stage IV Renal Cell Cancer AJCC V7
Interventions: DRUG: Pembrolizumab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open Label, Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous SAIT301 in Subjects With Advanced c-MET Positive (+) Solid Tumors Followed by Expansion in Selected Tumor Types
Status: COMPLETED
Conditions: Solid Tumors
Interventions: GENETIC: SAIT301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Determine the Antidepressant Effects of AZD6765
Status: COMPLETED
Conditions: Treatment Resistant Major Depressive Disorder
Interventions: DRUG: AZD6765|DRUG: Placebo to AZD6765
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-10353 in Adult Participants With Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: HS-10353 30mg oral capsules|DRUG: HS-10353 50mg oral capsules|DRUG: Placebo for HS-10353 30mg capsules|DRUG: Placebo for HS-10353 50mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Status: COMPLETED
Conditions: Adolescent Behavior
Interventions: BEHAVIORAL: As Safe As Possible|BEHAVIORAL: Brite|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Adherence With Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery
Status: COMPLETED
Conditions: Neoplasms Malignant|Surgery|Venous Thromboembolism|Prophylaxis|Adherence, Medication
Interventions: DRUG: Apixaban 2.5 milligram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Omega-3 Supplementation on Child Behavior Problems
Status: COMPLETED
Conditions: Antisocial|Aggressive|Externalizing Behavior Problems|Internalizing Behavior Problems
Interventions: DIETARY_SUPPLEMENT: omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraosseous Catheter Confirmation Study
Status: COMPLETED
Conditions: Critical Illness
Interventions: PROCEDURE: Standard intraosseous (IO) catheter confirmation procedure|PROCEDURE: Color flow Doppler intraosseous (IO) catheter confirmation procedure|PROCEDURE: Pressure transduction intraosseous (IO) catheter confirmation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic Esophageal Squamous Cell Cancer
Status: TERMINATED
Conditions: Esophageal Squamous Cell Cancer
Interventions: DRUG: Cisplatin, 5-FU|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose
Status: TERMINATED
Conditions: Prostate Cancer|Resistance Exercise|Androgen Deprivation Therapy
Interventions: DRUG: Zoladex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Research on a NTHF to Improve Pulmonary Function in Patients With Respiratory Failure
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: high-flow oxygen therapy device for tracheotomized patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brentuximab Vedotin Associated With Chemotherapy in Untreated Patients With Hodgkin Lymphoma.
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Doxorubicin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epacadostat, Cladribine and Cytarabine (ECC) in AML
Status: WITHDRAWN
Conditions: AML|Relapse
Interventions: DRUG: Epacadostat|DRUG: Cladribine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Treatment of Dry Eye
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Xeropthalmia
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Extension Study of GreenGene™ F in Previously Treated Patients Diagnosed With Severe Hemophilia A
Status: UNKNOWN
Conditions: Hemophilia A
Interventions: BIOLOGICAL: GreenGene™ F|BIOLOGICAL: GreenGene™ F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of SLx-4090 Combined With Statin Therapy Versus Statin Alone in Reducing LDL-C in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: SLx-4090|DRUG: SLx-4090|OTHER: Placebo|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Gene Expression in Women With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Double-Blind, Placebo-Controlled, Forced-Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Weeks in Patients With Stage 1 and Stage 2 Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: telmisartan 80 mg / hydrochlorothiazide 25 mg|DRUG: valsartan 160 mg / hydrochlorothiazide 25 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Multiple Doses of Itraconazole and Fluoxetine on the Pharmacokinetics of a Single Dose of RO5285119 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO5285119|DRUG: fluoxetine|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Right Ventricular Dysfunction in COPD Through Right Heart Catheterization, Imaging and Exercise
Status: RECRUITING
Conditions: COPD|Pulmonary Hypertension|Right Ventricular Dysfunction
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Effects of Chinese Medicine (Yi-Qi-Qing-Jie Herbal Compound) Combined With Immunosuppression Therapies in IgA Nephropathy Patients With High-risk of ESRD
Status: ACTIVE_NOT_RECRUITING
Conditions: IgA Nephropathy at High Risk of Developing ESRD
Interventions: DRUG: The Yi-Qi-Qing-Jie herbal compound|DRUG: Immunosuppressants|OTHER: Optimized Supportive Care|OTHER: Yi-Qi-Qing-Jie herbal compound placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Study to Evaluate the Efficacy and Safety of GH509 Versus Placebo in Patients With NASH/NAFLD
Status: RECRUITING
Conditions: NASH|NAFLD
Interventions: DRUG: GH509|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Poly-ICLC (Hiltonol) and Anti-PD1 or Anti-PD-L1
Status: TERMINATED
Conditions: Solid Cancer
Interventions: BIOLOGICAL: Poly-ICLC combination treatment with aPD-1 (Nivolumab or Pembrolizumab) or aPD-L1 (Atezolizumab or Durvalumab) over 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children
Status: RECRUITING
Conditions: Pediatric Disorder|Esophageal Diseases|Esophageal Stricture
Interventions: PROCEDURE: Esophageal dilatation with steroids injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEMETRA - ADVICE-002-2022
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Health Behavior|Life Style|Dietary Habits|Weight Loss|Diet, Healthy|Diet Habit|Body Weight|Nutrition Disorders|Nutrition, Healthy|Overweight and Obesity|Behavioral Disorder
Interventions: DEVICE: DTXO APP|DEVICE: PLACEBO APP - Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Nebulized Bronchodilators on Heart Rate
Status: COMPLETED
Conditions: COPD|Sepsis|Shock
Interventions: DRUG: Levalbuterol|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mobility Rehab, a Therapist-assisted System for Gait Rehabilitation
Status: UNKNOWN
Conditions: Parkinson Disease|Stroke|Multiple Sclerosis|Gait Disorders, Neurologic|Gait Disorder, Sensorimotor|Gait, Unsteady|Gait Ataxia|Gait, Stumbling|Gait, Shuffling
Interventions: OTHER: Feedback-assisted physical therapy|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valuation of Efficacy and Safety of Vitamin D3 Use in 80 Women Diagnosed With Fibromyalgia. Using FIQ Score and VAS.
Status: COMPLETED
Conditions: Fibromyalgia|D Vitamin Deficiency
Interventions: DRUG: D3 Vitamin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Training on Protein Expression in Skeletal Muscle Tissue After Exercise in Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: OTHER: Standard Treadmill Exercise|OTHER: Intermittent treadmill & resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossing Atheroma or Thrombus With ByCross Device for Revascularization of Peripheral Arteries of Diameter ≥ 3mm
Status: COMPLETED
Conditions: Arterial Occlusive Diseases
Interventions: DEVICE: ByCross Atherectomy and Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capacity of the Dual Combination Raltegravir/Etravirine to Maintain Virological Success in HIV-1 Infected Patients of at Least 45 Years of Age- ANRS 163 ETRAL
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: raltegravir and etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ATV|DRUG: RTV|DRUG: Tenofovi-Emtricitabine (TDF/FTC) tablet|DRUG: LPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Non-Invasive Blood Pressure System Data Collection in Comparison to Invasive Radial Arterial Pressure
Status: COMPLETED
Conditions: Blood Pressure Measurement
Interventions: DEVICE: GE Datex-Ohmeda Oxy-F Finger Clip Pulse Oximeter Sensor|DEVICE: Arrow® arterial catheterization kit (Teleflex)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinico-pathologic Correlative Study of 3T Magnetic Resonance Spectroscopy in the Localization of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Magnetic Resonance Spectroscopy (3Tesla)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Lymphoseek® vs. Albumin Nanocolloid in Head and Neck, Melanoma and Breast Cancer
Status: UNKNOWN
Conditions: Head Cancer|Neck Cancer|Melanoma|Breast Cancer
Interventions: DRUG: Lymphoseek|DRUG: Nanocoll
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Response of the Gut Microbiome and Circulating Metabolome to Diet in Children: Ancillary Study to KIDFIT (NCT03405246)
Status: COMPLETED
Conditions: Gastrointestinal Microbiome|Metabolome|Pediatric Obesity|Dietary Approaches to Stop Hypertension
Interventions: BEHAVIORAL: KIDFIT Healthy|BEHAVIORAL: KIDFIT Safe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Atrial Fibrillation Recurrence Following Cardioversion: the Role of Clinical Factors and Alpha Defensin Levels
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Colchicine Tablets|PROCEDURE: Cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab,Methotrexate and Lenalidomide in Newly Diagnosed Primary Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Recurrent Endometrial Carcinoma|Stage IV Endometrial Carcinoma
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamivudine for Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Relapsed/Refractory Solid Tumors
Interventions: DRUG: Lamivudine|DRUG: PD-L1 Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ribavirin in Combination With PEGASYS (Peginterferon Alfa-2a (40KD))in Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Trial of Locally Manufactured Typhoid Conjugate Vaccine 'Typhocon' in Bangladesh
Status: UNKNOWN
Conditions: Typhoid
Interventions: BIOLOGICAL: Typhoid Vi polysaccharide-diphtheria toxoid conjugate vaccine (Vi-DT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tasocitinib plus Methotrexate|DRUG: Tofacitinib plus placebo methotrexate|DRUG: Placebo tofacitinib plus Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ECG Triggered Dual Source CT for Non-invasive Pre-operative Cardiac Imaging in Morbid Obese Patients
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: RADIATION: standard protocol|RADIATION: enhanced protocol|RADIATION: enhanced obesity protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in Humans
Status: COMPLETED
Conditions: Cardiovascular Risk
Interventions: DIETARY_SUPPLEMENT: Energy Drink, Taurine, Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Session Intervention for Building Self-Compassion Habits-RCT
Status: COMPLETED
Conditions: Transdiagnostic Psychopathology
Interventions: BEHAVIORAL: Single Session Intervention Leveraging an Ultra-Brief Self-Compassion Exercise|BEHAVIORAL: Finger-Tapping Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Different Doses of Nulbuphine _bupivacaine in TAP Block in Cancer Abdominal Surgeries
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Group I (BN10)|PROCEDURE: Active Comparator:Group ll (BN20)|PROCEDURE: Active Comparator:Group lll (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation With Spinal Stimulation Methods
Status: RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Injury at C5-C7 Level|Paraplegia, Spinal|Paraplegia, Incomplete
Interventions: DEVICE: spinal stimulation-DCS|OTHER: spinal stimulation-sham DCS|OTHER: spinal stimulation-EPS|OTHER: sham spinal stimulation-EPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II (Treatment) Study of Oxaliplatin and Capecitabine in Advanced Head and Neck Malignancies
Status: COMPLETED
Conditions: Head or Neck Cancer
Interventions: DRUG: Oxaliplatin, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapivirine Gel Rectal Safety and PK Study
Status: WITHDRAWN
Conditions: HIV 1 Infection
Interventions: DRUG: Dapivirine gel (0.05%)|OTHER: Universal HEC placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fecal Transplant for Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: BIOLOGICAL: fecal transplant|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health
Status: COMPLETED
Conditions: Aging|Wrinkle|Skin Elasticity|Healthy|Hydration
Interventions: DIETARY_SUPPLEMENT: FloraGLO Lutein|DIETARY_SUPPLEMENT: Safflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Pembrolizumab and Lenvatinib in Advanced Well-differentiated Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Neuroendocrine Carcinoma|Neuroendocrine Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Efficacy and Tolerability of Antistax Film-coated Tablets in Patients With Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Venous Insufficiency
Interventions: DRUG: Red vine leaf extract (AS 195)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sexual Counseling Given According to the PLISSIT Model on FSFI, MAS and SQOL-F of Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopause|Sexual Function|Marital Relationship
Interventions: OTHER: Sexual counseling according to the PLISSIT model, randomized pretest-posttest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Nudges on Downloads of COVID-19 Exposure Notification Smartphone Apps: A Randomized Trial
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: Self-Benefit/Social Norm|BEHAVIORAL: Self-Benefit/No Social Norm|BEHAVIORAL: Other Benefit/Social Norm|BEHAVIORAL: Other Benefit/No Social Norm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Aerosol High-pressure Chemotherapy for Women With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: chemotherapy with doxorubicin and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactoserum (Dermacyd Femina®) and Prevention of Recurrence of Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: Lactoserum (Dermacyd Femina®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lurtotecan Liposome in Treating Patients With Advanced or Recurrent Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: lurtotecan liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Non-surgical Interventions for the Trigger Finger: a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Trigger Finger
Interventions: PROCEDURE: Therapeutic modalities: Orthotic (Group 1)|PROCEDURE: Therapeutic modalities: LLLT (Group 2)|PROCEDURE: Therapeutic modalities: Paraffin (Group 3)|PROCEDURE: Corticosteroid injection (Group 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide in Subject With Low and Intermediate-1 Risk MDS and Without Chromosome 5 Abnormality.
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Lenalidomide|DRUG: Epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Personalized Radiation Therapy With Standard Radiation Therapy in People With HPV-Positive Throat Cancer
Status: RECRUITING
Conditions: HPV-Related Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: FMISO-PET Scan|COMBINATION_PRODUCT: Chemoradiation|COMBINATION_PRODUCT: Chemoradiation|OTHER: Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Assess the Effect of Omeprazole on the Pharmacokinetics of VELCADE in Patients With Either Advanced Solid Tumors or Non-Hodgkin's Lymphoma.
Status: COMPLETED
Conditions: Tumors|Non-Hodgkins's Lymphoma
Interventions: DRUG: omeprazole and bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoring Tissue and Evaluating Novel Treatments for Efficacy in Wounds
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Lavior Diabetic Wound Gel|DRUG: Smith & Nephew Solosite Gel Hydrogel Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of GLP-1 Infusion in Comparison to an Insulin Infusion Protocol to Reach Normoglycemia Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Hyperglycemia
Interventions: DRUG: GLP-1|DRUG: Human regular insulin intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block With Brachial Plexus Block for Upper Arm Arteriovenous Fistula Surgery
Status: COMPLETED
Conditions: Regional Anesthesia Success
Interventions: PROCEDURE: Subcutaneous infiltration of intercostobrachial nerve|PROCEDURE: T2 paravertebral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dutasteride (GI198745) In Benign Prostatic Hyperplasia Subjects
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted Rehabilitation of Ankle Fractures: Efficacy and Comparison With Traditional Methods
Status: COMPLETED
Conditions: Ankle Fractures
Interventions: DEVICE: Specific ankle rehabilitation by ARBOT device|OTHER: General Rehabilitation|OTHER: Specific ankle rehabilitation performed by physiotherapist|DEVICE: Specific ankle rehabilitation by Biodex System 3 dynamometer|DEVICE: Specific ankle rehabilitation by ProKin PK254 platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Using Integuseal as Microbial Sealant for Arterial Bypass Surgery on Lower Extremities
Status: TERMINATED
Conditions: Arterial Obstructive Diseases
Interventions: PROCEDURE: Application of Integuseal sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Pediatric Artificial Pancreas (PEDAP) Trial of Control-IQ Technology in Young Children in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Tandem t:slim X2 with Control-IQ Technology Pro|DEVICE: Standard Care (SC)|DEVICE: Tandem t:slim X2 with Control-IQ Technology V1.5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Biological Effects Of The Use Of Probiotic VSL#3 In Patients With Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DIETARY_SUPPLEMENT: Poly-biotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Studies on Aldosterone and Vascular Function
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: aldosterone|DIETARY_SUPPLEMENT: low or high sodium diet|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Protein-Energy Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritious Shake|BEHAVIORAL: Nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: TAS-102|RADIATION: Photon SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migration in Total Hip Arthroplasty With a Cemented BiMobile Cup: Better Stability With More Cement?
Status: RECRUITING
Conditions: Total Hip Arthroplasty|Osteoarthritis, Hip
Interventions: PROCEDURE: BiMobile standard cement|PROCEDURE: BiMobile larger cement|PROCEDURE: Avantage standard cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis
Status: NOT_YET_RECRUITING
Conditions: Endocarditis Infective
Interventions: DRUG: Cefaclor|DRUG: Ciprofloxacin Tablets|DRUG: Ciprofloxacin Injection|DRUG: Clindamycin Oral Capsule|DRUG: Clindamycin Injection|DRUG: Dicloxacillin Oral Capsule|DRUG: Dicloxacillin|DRUG: Fusidic Acid Only Product in Oral Dose Form|DRUG: Fusidic Acid Only Product in Parenteral Dose Form|DRUG: Levofloxacin Oral Tablet|DRUG: Levofloxacin Injection|DRUG: Linezolid Oral Tablet|DRUG: Linezolid Injectable Product|DRUG: Moxifloxacin tablet|DRUG: Moxifloxacin Injectable Product|DRUG: Rifampicin Only Product in Oral Dose Form|DRUG: Rifampicin Only Product in Parenteral Dose Form|DRUG: Sulfamethoxazole / Trimethoprim Oral Tablet [Bactrim]|DRUG: Sulfamethoxazole / Trimethoprim Injectable Product|DRUG: Tedizolid Oral Tablet|DRUG: Tedizolid Injection|DRUG: Amoxicillin Capsules|DRUG: Amoxicillin|DRUG: Cefaclor Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Histological Quality of Biopsy Samples Obtained With Multibite Forceps
Status: COMPLETED
Conditions: Helicobacter Pylori Infection|Celiac Disease
Interventions: DEVICE: MultCROC multibite forcep|DEVICE: Conventional double bite forcep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacological Preparation of the Cervix for Hysteroscopy
Status: COMPLETED
Conditions: Uterine Polyp|Uterine Bleeding|Endometrium; Senility
Interventions: DRUG: estradiol|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT