pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Delusional Disorder|Major Depressive Disorder With Psychotic Features
Interventions: BEHAVIORAL: Collaborative Decision Skills Training|BEHAVIORAL: Leveling Up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet Therapy for Silent Brain Infarction
Status: UNKNOWN
Conditions: Brain Infarction
Interventions: DRUG: Aspirin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Vitamin D in Patients With Diabetic Peripheral Neuropathy to Alleviate Pain and Improvement of Symptoms
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telbivudine Therapy in HBeAg-positive Pregnant Women to Prevent Mother-to-infant Transmission of HBV
Status: COMPLETED
Conditions: HBV
Interventions: DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Non-interventional Study to Assess the Influence of Automated Optical Coherence Tomography Image Enrichment With Segmentation Information on Disease Activity Assessment in Patients Treated With Licensed Anti- VEGF Injections
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: brolucizumab|DRUG: ranibizumab|DRUG: aflibercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|HER-2 Protein Overexpression|HER-2 Gene Amplification|HER2 Gene Mutation
Interventions: DRUG: ORM-5029
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Sargramostim in Treating Patients With Cancer of the Uterus
Status: TERMINATED
Conditions: Sarcoma
Interventions: BIOLOGICAL: sargramostim|DRUG: cisplatin|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Follow-up in Pediatric Intensive Care Unit
Status: RECRUITING
Conditions: Intensive Care Psychosis
Interventions: OTHER: Questionnaires : PHQ-9 (Kroenke, 2001), the PSC (Sheldrick, 2012), the ASQ-SE (Squires, 2015), the PedsQL (Varni, 1999)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Three Different Local Cold Applications on Pain and Ecchymosis in Subcutaneous Heparin Injections
Status: COMPLETED
Conditions: Pain|Ecchymosis
Interventions: OTHER: Thermo mechanical device|OTHER: local coolant spray|OTHER: ıce battery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Medial Pivot Versus Symmetric Insert Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: total knee arthroplasty with medial pivot tibial insert or symmetrical insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)
Status: SUSPENDED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BMF-219
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Involving Neoadjuvant Chemoradiotherapy With Hypofractionated Radiotherapy in Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: RADIATION: Hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Study of XELOX Chemotherapy With or Without Surgery of Primary Lesion for Colon Cancer Patients
Status: UNKNOWN
Conditions: Metastatic Colon Cancer
Interventions: PROCEDURE: resection of primary lesion|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduced Nicotine Cigarette Purchasing Decisions
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Full Nicotine Cigarettes|DRUG: Reduced Nicotine Cigarettes|BEHAVIORAL: Average Nicotine Expectancy|BEHAVIORAL: Very Low Nicotine Expectancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lower Lugol's Solution Concentration on Reducing the Adverse Symptoms of Chromoendoscopy With Iodine Staining
Status: COMPLETED
Conditions: Mucosal Irritation|Image Quality
Interventions: DRUG: 1.2% Lugol's solution|DRUG: 1.0% Lugol's solution|DRUG: 0.8% Lugol's solution|DRUG: 0.6% Lugol's solution|DRUG: 0.4% Lugol's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Evaluating Feasibility and Effectiveness of Computerized Mathematic Training
Status: COMPLETED
Conditions: Math Teachers (Grades 2-8)|Math Students (Grades 2-8)
Interventions: OTHER: Prodigy Math Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Outcomes of Small-incision Lenticule Extraction (SMILE) Using Vector Planning Method.
Status: COMPLETED
Conditions: Myopic Astigmatism
Interventions: PROCEDURE: SMILE using manifest refraction planning|PROCEDURE: SMILE using vector planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ICON Study: Outcomes After FMT for Patients With IBD and CDI
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Clostridium Difficile Infection
Interventions: DRUG: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: STAT Inhibitor OPB-111077|DRUG: Decitabine|DRUG: Venetoclax|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics Study of Inhaled QBW276 in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Pulmonary Cystic Fibrosis
Interventions: OTHER: Placebo|DRUG: QBW276
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Bupropion SR|DRUG: Nicotine Patch|DRUG: Placebo Patch and Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Evaluation of the P2Et Extract in Patients With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Quality of Life|Tumor, Breast
Interventions: DRUG: P2Et (Caesalpinia spinosa extract)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids in Elderly Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Heart Failure|Myocardial Revascularization|Atrial Fibrillation
Interventions: DRUG: Pikasol|OTHER: Corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Evaluate The Pharmacokinetic, Safety And Tolerability Of Single Or Multiple Subcutaneous Doses of Recifercept
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Recifercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retinal, Cerebral and Vascular Precursor Markers of Cerebral Small Vessel Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: PROCEDURE: Vascular and ophthalmological examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine as Post Exposure Prophylaxis for SARS-CoV-2(HOPE Trial)
Status: WITHDRAWN
Conditions: Contact Person From COVID-19 Confirmed Patient
Interventions: DRUG: Hydroxychloroquine as post exposure prophylaxis|OTHER: Others(No intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Ezetimibe|DRUG: Cholecalciferol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Buddy Relationships in DermatoloGic Excisions for Skin Cancer
Status: COMPLETED
Conditions: Skin Cancer Face|Quality of Life|Surgical Wound|Peer Mentorship
Interventions: BEHAVIORAL: Peer Mentorship Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ITF2984 Repeated Doses Study in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: ITF2984 (500, 1000, 2000 mcg bid for 7 days)|DRUG: octreotide 50 mcg tid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Performance of Certain Prevail Implants Used in Short Fixed Cases
Status: COMPLETED
Conditions: Partial Edentulism|Tooth Disease
Interventions: DEVICE: Osseotite Certain Prevail|DEVICE: Osseotite Certain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US-MR Image Fusion-guided Percutaneous Transforaminal Endoscopic Discectomy for the Treatment of Lumbar Disc Herniation
Status: UNKNOWN
Conditions: Lumbar Herniated Disc
Interventions: PROCEDURE: US-MR image fusion-guided PTED|PROCEDURE: fluoroscopy-guided PTED
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC)
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bobath Approach With Core Stability to Improve Balance in Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Balance; Distorted
Interventions: DIAGNOSTIC_TEST: Bobath Technique with core stability|OTHER: Conventional treatment for balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
Status: RECRUITING
Conditions: Migraine|Migraine With Aura|Migraine Without Aura|Chronic Migraine
Interventions: DRUG: Atogepant 60 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: China PEACE II: Quality Improvement for Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BEHAVIORAL: Quality improvement strategies and tools|BEHAVIORAL: Process optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Egg Effects on Atherogenic Dyslipidemias, Glucose Metabolism and Inflammation in Diabetic Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus|Inflammation
Interventions: OTHER: Egg, one a day, for breakfast|OTHER: Oatmeal, one cup a day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Scoliosis in Patients With Duchenne Muscular Dystrophy Using Portable Seat Device
Status: RECRUITING
Conditions: Scoliosis Neuromuscular|Duchenne Muscular Dystrophy|Lordosis Lumbar
Interventions: DEVICE: Portable seat device devised to maintain lumbar lordosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Oesophageal Cancer|Oesophageal Cancer Metastatic|Esophageal Cancer Metastatic|Esophageal Cancers NOS|Oesophageal Cancer Nos|GastroEsophageal Cancer|Gastrooesophageal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up of Patients With Parkinson's Disease Who Had Administered of A9-DPC in SB-PD-001 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: Allogenic embryonic stem cellderived A9 dopamine progenitor cell (A9-DPC)_Low Dose|BIOLOGICAL: Allogenic embryonic stem cellderived A9 dopamine progenitor cell (A9-DPC)_High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Therapeutic Hypothermia on Deceased Donor Renal Graft Outcomes - a Randomized Controlled Trial From the Region 5 Donor Management Goals Workgroup
Status: COMPLETED
Conditions: Deceased Organ Donor|Mild Hypothermia|Renal Function
Interventions: OTHER: Hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fibrinogen Concentrate (FGTW) in Trauma Patients, Presumed to Bleed (FI in TIC)
Status: COMPLETED
Conditions: Trauma|Massive Hemorrhage
Interventions: DRUG: Human Fibrinogen Concentrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gamma Nail Versus Dynamic Hip Screw for the Treatment of Unstable Intertrochanteric Fractures
Status: UNKNOWN
Conditions: Intertrochanteric Femoral Fractures
Interventions: DEVICE: Gamma-3 Nail|DEVICE: DHS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity and Safety of Endoscopic Ultrasonography-guided Laser Ablation for Refractory Neoplasms
Status: UNKNOWN
Conditions: Refractory Neoplasms
Interventions: PROCEDURE: EUS-guided laser ablation for refractory neoplasms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Betaine Supplementation During Breastfeeding
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Betaine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL)
Status: SUSPENDED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Liposomal cytarabine|DRUG: Intrathecal triple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure Effect on Air Trapping in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: positive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of EED on Zn Absorption and Retention in Children From a MNP
Status: COMPLETED
Conditions: Environmental Enteric Dysfunction|Zinc Deficiency
Interventions: DIETARY_SUPPLEMENT: Micronutrient Powder (MNP) + 15 mg Zn|DIETARY_SUPPLEMENT: MNP + 10 mg Zn|DIETARY_SUPPLEMENT: MNP + 5 mg Zn|DIETARY_SUPPLEMENT: MNP without Zn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Busulfan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer
Status: UNKNOWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Breast Carcinoma
Interventions: DRUG: Lutetium Lu 177 Dotatate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.
Status: RECRUITING
Conditions: Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric Adenocarcinoma|Hepatocellular Carcinoma|Biliary Tract Carcinoma|Colorectal Adenocarcinoma
Interventions: RADIATION: Hypofractionated radiotherapy/SBRT（5-10Gy/fx，3-5 fx）|DRUG: Anti-PD-1 monoclonal antibody|DRUG: Oxaliplatin and Capecitabine|DRUG: Anti-VEGF 15mg/kg|DRUG: Anti-VEGF 7.5mg/kg|DRUG: Gemcitabine and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Citalopram for Sx/Util in Acute Coronary Syndrome Patients
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Evaluating the Efficacy and Safety of Dexamethasone Compared to Placebo in Patients With Severe Influenza
Status: WITHDRAWN
Conditions: Influenza
Interventions: DRUG: Grup 1 placebo|DRUG: Grup 2 dexametasona
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Type 2 Diabetes Peer Counseling on Behavioral, Metabolic, and Health Outcomes Among Latinos
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: BEHAVIORAL: Diabetes Peer Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Two Nicotine Lozenges in Fasting Conditions in Healthy Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Nicotine Prototype Mini lozenge|DRUG: Nicorette Mini Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Atorvastatin 80mg|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Interferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: recombinant interferon alfa|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pain Science Education Administered in Full or Fractioned Dosage Modes for Temporomandibular Disorders
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: BEHAVIORAL: Fractioned Pain Science Education (FPSE)|BEHAVIORAL: Full Dosage Mode Pain Science Education (FDPSE)|OTHER: Manual Therapy|OTHER: Orofacial and Neck Exercises (ONE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Differences in Effortful Control
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Methylphenidate|DRUG: Placebo|BEHAVIORAL: Easy Behavioral Task|BEHAVIORAL: Hard Behavioral Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%)
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Propranolol 0.2% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mixed Gel of Hydrocortisone and Aluminium Phosphate Preventing Endoscopic Submucosal Dissection Postoperative Stenosis for Patients With Large Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Stenosis Acquired
Interventions: OTHER: Hydrocortisone sodium succinate mixed with Aluminium Phosphate gel (route of administration)|OTHER: Triamcinolone Acetonide (route of administration)|OTHER: Prednisone (route of administration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: C1K 150mg|DRUG: C1K 300mg|DRUG: Placebo with the same volume of C1K 300mg|DRUG: C1K 600mg|DRUG: Placebo with the same volume of C1K 600mg|DRUG: C1K 900mg|DRUG: Placebo with the same volume of C1K 900mg|DRUG: C1K 1200mg|DRUG: Placebo with the same volume of C1K 1200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Carcinoma|Platinum-resistant Ovarian Cancer|Recurrent Ovarian Carcinoma|Albumin-bound Paclitaxel|Bevacizumab|Survival Outcomes|Adverse Events
Interventions: COMBINATION_PRODUCT: Albumin-bound paclitaxel and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Direct Current Stimulation of the Spinal Cord for Treatment of Spasticity in Multiple Sclerosis
Status: UNKNOWN
Conditions: Spastic Parapareses
Interventions: DEVICE: Transcutaneous Spinal Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Efficacy of Estetrol in Postmenopausal Women With Advanced Estrogen Receptor Positive (ER+) Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Estetrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vacuum-formed Retainer Versus Bonded Retainer to Prevent Relapse After Orthodontic Treatment
Status: COMPLETED
Conditions: Orthodontics|Retention
Interventions: DEVICE: CTC retainer|DEVICE: Essix retainer maxilla|DEVICE: Essix retainer mandible|PROCEDURE: Alginate impression|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arginine Supplementation to Improve Cardiovascular and Endothelial Function After NSAID Treatment
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Celecoxib|OTHER: Placebo|OTHER: L-arginine + placebo|OTHER: L-arginine + celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rehabilitation Robotics, Cognitive Skills Training and Function
Status: TERMINATED
Conditions: Stroke|Cerebrovascular Accident
Interventions: BEHAVIORAL: Robot-Assisted Therapy (RT)|BEHAVIORAL: Robot + Active Learning Program(RT-ALPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin in Postmenopausal Women With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Hypertension Care in Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Diabetes|Telemedicine
Interventions: BEHAVIORAL: Enhanced Usual Care Group|OTHER: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)
Status: COMPLETED
Conditions: Coronary Disease|Hypercholesterolemia
Interventions: DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Binge Eating Disorder
Status: NOT_YET_RECRUITING
Conditions: Binge-Eating Disorder
Interventions: DEVICE: TMS followed by Sham TMS|DEVICE: Sham TMS followed by TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tiotropium Inhalation Capsules and Atrovent MDI in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium inhalation capsules (18 mcg once daily)|DRUG: Atrovent MDI (2 puffs of 20 mcg(q.i.d.) in patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Molecular Biomarkers for Lu-177 DOTATATE Therapy in Midgut Neuroendocrine Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Midgut Neuroendocrine Tumors
Interventions: BIOLOGICAL: non-drug intervention type
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Stimulation and Sleep Quality. An Innovative Intervention for Insomnia
Status: ENROLLING_BY_INVITATION
Conditions: Insomnia|Insomnia Type; Sleep Disorder
Interventions: OTHER: Personalized cognitive stimulation|OTHER: Sham cognitive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
Status: RECRUITING
Conditions: Heart Septal Defect|Heart Septal Defects, Atrial|Heart Defects, Congenital|Cardiovascular Abnormalities|Cardiovascular Diseases|Heart Diseases|Congenital Abnormalities
Interventions: DEVICE: reSept ASD Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nephrectomy Specimen for Intracranial Aneurysm Development in ADPKD
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Aneurysm, Brain|Polycystic Kidney Diseases
Interventions: PROCEDURE: Kidney transplantation and nephrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Emtricitabine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Colony-Stimulating Factors to Relieve Neutropenia in Patients With Recurrent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Neutropenia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: cytarabine|DRUG: etoposide|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-arterial Microplasmin Administration in Patients With Acute Peripheral Arterial Occlusion
Status: TERMINATED
Conditions: Arterial Occlusive Diseases
Interventions: DRUG: Microplasmin|DRUG: Microplasmin|DRUG: Microplasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab vs Dacarbazine in Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Malignant Melanoma|Unresectable Malignant Melanoma
Interventions: DRUG: Bevacizumab|DRUG: Propranolol|DRUG: Enalapril|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Benign Breast Deformities and Post-Segmental Mastectomy Breast Deformities With Autologous Fat Grafting (AFT)
Status: WITHDRAWN
Conditions: Breast Cancer|Lumpectomy|Mastectomy, Segmental
Interventions: PROCEDURE: Autologous Fat Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BIOLOGICAL: SB623 cells|PROCEDURE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COgnitive REhabilitation in Pediatric Patients With sABI From Vegetative State to Functional Recovery
Status: COMPLETED
Conditions: Acquired Brain Injury|Development, Child
Interventions: BEHAVIORAL: Neuropsychological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Study on the Long Term Safety of Kuvan® Treatment in Patients With Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or BH4 Deficiency
Status: COMPLETED
Conditions: Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or Tetrahydrobiopterin (BH4) Deficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GLP 1 for Intraoperative Glycemic Control
Status: COMPLETED
Conditions: Hyperglycemia|Hypoglycemia
Interventions: BIOLOGICAL: GLP 1|BIOLOGICAL: normal saline solution placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-MFBG PET Imaging of the Norepinephrine Transporter in Neural Crest and Neuroendocrine Tumors
Status: TERMINATED
Conditions: Neural Crest Tumor|Neuroendocrine Tumors
Interventions: DRUG: (18F)MFBG|DEVICE: PET/CT|OTHER: Venous blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Effects and Tolerance of the RV4986A Lotion in Men With AGA After Hair Transplant
Status: COMPLETED
Conditions: Androgenic Alopecia
Interventions: OTHER: RV4986A lotion|OTHER: RD0057H shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy Followed by Biological Therapy in Treating Patients With Stage IV Melanoma That Cannot be Treated With Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: sargramostim|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of 10 cm^2 Rivastigmine Patch in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine 5 and 10 cm^2 patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real and Virtual Environments in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: ASD - Abstract task|DEVICE: ASD - Tangible task|DEVICE: TD - Abstract task|DEVICE: TD - Tangible task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing
Status: TERMINATED
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Percutaneous Electrolysis on Endogenous Pain Modulation
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Isolated needling procedure|PROCEDURE: Low intensity percutaneous electrolysis|PROCEDURE: High intensity percutaneous electrolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis
Status: TERMINATED
Conditions: Herpes Labialis|Herpes Simplex Virus
Interventions: DRUG: Glutamine|DRUG: Glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
Status: NOT_YET_RECRUITING
Conditions: ACL|Anterior Cruciate Ligament|ACL Injury
Interventions: BEHAVIORAL: Placebo Split-Belt Training|BEHAVIORAL: Split-Belt Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Arginine on Biofilm Composition, Architecture and Metabolism
Status: RECRUITING
Conditions: Dental Caries|Dental Plaque|Microbial Colonization
Interventions: OTHER: Arginine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Plant Omega-3 and Omega-6 Fatty Acids on Exercise Performance
Status: UNKNOWN
Conditions: Effect of Essential Fatty Acids on Exercise Performance
Interventions: DIETARY_SUPPLEMENT: corn syrup|DIETARY_SUPPLEMENT: Polyunsaturated fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Aurora A Kinase Inhibitor MLN8237 in Treating Patients With Unresectable Stage III-IV Melanoma
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IIIc Melanoma|Stage IV Melanoma
Interventions: OTHER: laboratory biomarker identification and analysis|PROCEDURE: biopsy|OTHER: immunohistochemistry/tissue microarrays|GENETIC: TdT-mediated dUTP nick end labeling assay|OTHER: mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-menopausal Women Osteoporosis(Phase III)
Status: COMPLETED
Conditions: Postmenopausal Women Osteoporosis
Interventions: DRUG: risedronate combine|DRUG: Risedronate|DRUG: Placebo(for Risedronate)|DRUG: Placebo(for risedronate combine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Versus Placebo for Benzodiazepine Discontinuation in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Affective Disorder
Interventions: DRUG: Placebo|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Doppler to Predict Acute Kidney Injury (AKI) in ARDS Patients. (RED-AKI Study)
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|ARDS, Human
Interventions: DIAGNOSTIC_TEST: ARDS+AKI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial Assessing the Efficacy of a Short Course of Intravenous Antibiotic Followed by Oral Antibiotic in Uncomplicated Acute Diverticulitis
Status: COMPLETED
Conditions: Diverticulitis
Interventions: DRUG: amoxicillin plus clavulanic acid|DRUG: amoxicillin plus clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strength Training Augmenting Rehabilitation
Status: UNKNOWN
Conditions: Muscle Disuse Atrophy
Interventions: PROCEDURE: Orthopedic immobilization|OTHER: Unilateral resistance training|OTHER: Bilateral resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Whether Functional Strength Training Can Enhance Recovery of Mobility After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Conventional UK Physical therapy|BEHAVIORAL: Increased intensity of UK conventional physical therapy|BEHAVIORAL: UK conventional physical therapy plus functional strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
Status: RECRUITING
Conditions: Opioid Use|Pain|Marijuana Use
Interventions: DRUG: Medical Marijuana|BEHAVIORAL: Prescription Opioid Taper Support (POTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tibolone and Placebo in Adjunct to Antidepressant Medication for Women With Menopausal Depression
Status: COMPLETED
Conditions: Menopausal Depression
Interventions: DRUG: Tibolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence in Patients Receiving PegIntron/Rebetol for Hepatitis C in Conjunction With a Psychotherapy Support Program (Study P04252)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepacivirus
Interventions: BIOLOGICAL: Peginterferon alfa-2b (PegIntron)|DRUG: Rebetol (Ribavirin)|BEHAVIORAL: Psychotherapy support program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Combined ALLR With Single Bundle and Double Bundle Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Single-bundle ACL combined anterolateral ligament reconstruction|PROCEDURE: Double-bundle ACL combined anterolateral ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: [18F]GTP1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
Status: COMPLETED
Conditions: Burns
Interventions: DRUG: Oleogel-S10 ointment|DEVICE: Octenilin® wound gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Food Solutions for Cancer Patients
Status: COMPLETED
Conditions: Cancer Patients|Taste Disorders|Food Selection
Interventions: BEHAVIORAL: Texture-modified foods for cancer patients (Stage 2)|BEHAVIORAL: Taste-optimised foods for cancer patients (Stage 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Investigational Immuno-therapy Study to Determine the Safety of Urelumab Given in Combination With Nivolumab in Solid Tumors and B-cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Advanced Solid Tumors|Advanced B-cell NHL
Interventions: BIOLOGICAL: Urelumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial Assessing the Effect of Topical Tranexamic Acid on Risk of Hematoma in Breast Surgery
Status: RECRUITING
Conditions: Hematoma Postoperative
Interventions: DRUG: Tranexamic acid injection|OTHER: No additional irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Physical Activities Randomized Controlled Trial in Mild/Moderate Depression Participants: SONRIE Project
Status: COMPLETED
Conditions: Exercise|Physical Fitness|Depression|Adult ALL|Psychological
Interventions: BEHAVIORAL: Exercise and psychological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CP-675,206 With Neoadjuvant Hormone Therapy in Patients With High Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: CP-675,206 and leuprolide acetate and bicalutamide|DRUG: leuprolide acetate and bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT