pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Application of Stem Cell Educator Therapy in Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata|Alopecia Totalis|Alopecia Universalis
Interventions: COMBINATION_PRODUCT: Stem Cell Educator therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stepwise and One Step Techniques In Deep Dentin Lesion
Status: UNKNOWN
Conditions: Dental Caries, Dental Pulp Exposure
Interventions: PROCEDURE: Stepwise Excavation|PROCEDURE: One Step Excavation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Balloon-based Cryoablation of Human Esophageal Epithelium
Status: COMPLETED
Conditions: Barrett's Esophagus|Esophageal Cancer
Interventions: DEVICE: Cryoballoon Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Target Kinase Inhibitor and Anti-Programmed Death-1 Antibody in Patients With Advanced Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: multiple tyrosine kinase inhibitor(mTKI) Combined with anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ctDCS During Balance Training on Cerebellar Ataxia
Status: UNKNOWN
Conditions: Cerebellar Ataxia|Cerebellum; Injury|Balance
Interventions: DEVICE: cerebellar transcranial direct current stimulation|DEVICE: Sham cerebellar transcranial direct current stimulation|OTHER: Balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application
Status: COMPLETED
Conditions: Chronic Renal Insufficiency|Serum Creatinine Concentration|Contrast Media Exposition
Interventions: DRUG: sodium 2-mercaptoethane sulfonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of IV Vitamin C in Reducing Oxidative Stress Associated With Free Flap Surgery
Status: RECRUITING
Conditions: Oxidative Stress|Ischemia-reperfusion Injury
Interventions: DRUG: Intravenous Ascorbate|DRUG: Normal Saline 10 mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Iron Chelator Deferiprone in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: deferiprone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of a Nitric Oxide Supplementation on Pre- and Mildly Hypertensive Adults
Status: TERMINATED
Conditions: Pre-hypertension
Interventions: DIETARY_SUPPLEMENT: Neo40 Daily®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preimplantation Genetic Testing in Women of Advanced Maternal Age
Status: RECRUITING
Conditions: Infertility, Female
Interventions: PROCEDURE: Preimplantation genetic testing for aneuploidy (PGT-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Leaving in Situ Colorectal Polyps.
Status: RECRUITING
Conditions: Colonic Neoplasms
Interventions: BEHAVIORAL: Leave In Situ|BEHAVIORAL: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Impact Laparoscopy Concept Versus Conventional Laparoscopy
Status: TERMINATED
Conditions: Ambulatory Laparoscopic Hysterectomy
Interventions: DEVICE: Low Impact Laparoscopy|DEVICE: conventional laparoscopy|OTHER: Visual Analog Scale (VAS) for Pain|OTHER: Saint-Antoine Pain Questionnaire (QDSA)|OTHER: post-operative questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: RADIATION: radiation therapy|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Combination With Cisplatin-5-fluorouracil for the Induction Treatment of Nasopharyngeal Carcinoma in Children and Adolescents
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms|Carcinoma
Interventions: DRUG: docetaxel|DRUG: cisplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sweet Taste Responsiveness in Relation to Insulin, Leptin and Adiposity Among Obese Treatment Seeking Children
Status: WITHDRAWN
Conditions: Pediatric Obesity
Interventions: DIAGNOSTIC_TEST: Serum insulin level|DIAGNOSTIC_TEST: Serum Leptin test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Status: RECRUITING
Conditions: Glioblastoma, IDH-wildtype
Interventions: DRUG: Metformin|RADIATION: Radiation IMRT|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients
Status: UNKNOWN
Conditions: HIV Infections|Diarrhea|Bacterial Vaginosis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GR-1 + Lactobacillus reuteri RC-14|DIETARY_SUPPLEMENT: Placebo|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study
Status: WITHDRAWN
Conditions: Constitutional Mismatch Repair Deficiency Syndrome|Hematopoietic and Lymphoid Cell Neoplasm|Lynch Syndrome|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Neuroblastoma|Recurrent Primary Central Nervous System Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Neuroblastoma|Refractory Primary Central Nervous System Neoplasm|Xeroderma Pigmentosum
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Treatment Outcomes of b-CPAP vs Oxygen Therapy in Preterm Babies Presenting With RDS at KCMC
Status: COMPLETED
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: DEVICE: bCPAP Arm|OTHER: Oxygen Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Prednisone, Vincristine, Daunorubicin, PEG-L-asparaginase, Erwinia L-asparaginase, Doxorubicin, Cyclophosphamide, Cytarabine, Thioguanine|DRUG: Clofarabine, Methotrexate, Mercaptopurine, Dexamethasone, Etoposide, Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of the Ophthalmic Gel PRO-167 Versus Corneregel® on Healthy Subjects.
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Syndrome of Unspecified Lacrimal Gland
Interventions: DRUG: PRO-167|DRUG: Corneregel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Postoperative Analgesia Herniorrhaphy Study
Status: WITHDRAWN
Conditions: Analgesia
Interventions: DRUG: HTX-011|DRUG: Bupivacaine HCl|DRUG: HTX-011|DRUG: HTX-011|DRUG: HTX-011|DEVICE: Luer Lock Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Oseltamivir From Oseltamivir 75 mg Caps (Pharmacare PLC, Palestine) and Tamiflu® 75 mg Caps (Hoffmann-La Roche, Switzerland)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oseltamivir|DRUG: Tamiflu®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Anesthesia Technique in COVID-19 Positive Hip Fracture Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Fractures|COVID-19|General Anesthesia|Spinal Anesthesia
Interventions: PROCEDURE: Hip Fracture Surgery|OTHER: COVID-19 infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).
Status: RECRUITING
Conditions: Mitochondrial Diseases|Mitochondrial Myopathies|Mitochondrial Encephalomyopathies|MELAS|MERRF
Interventions: BEHAVIORAL: Promoting Resilience in Stress Management (PRISM)|BEHAVIORAL: Clinical-focused narrative (CFN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder|Alcohol Use Disorder
Interventions: DRUG: Pregnenolone 250 mg|DRUG: Pregnenolone 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: ribavirin|DRUG: ribavirin|DRUG: Peginterferon alfa-2a|DRUG: epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of TC-5619 in Healthy Elderly Subjects and Subjects With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: TC-5619|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of an IMB-based Intervention for Reducing Sweetened Beverages Consumption in Preschool Children
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Sugar-sweetened beverage reduction education for preschool children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment Strategy of Vasovagal Syncope
Status: RECRUITING
Conditions: Syncope, Vasovagal
Interventions: PROCEDURE: Cardioneuroablation|DRUG: Midodrine Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Solid/Crushed/Dissolved Forms of Biktarvy®
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: receive dissolved form of BIKTARVY®|DRUG: receive crushed form of BIKTARVY®|DRUG: receive solid form of BIKTARVY®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Psychoeducation Focused on Reducing Internalized Stigma
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Treatment Adherence|Stigma, Social
Interventions: OTHER: Psychoeducation Focused on Reducing Internalized Stigma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Follicular Lymphoma With High Dose Therapy and Stem Cell Support Followed by Rituximab and Alpha Interferon
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|DRUG: Alpha Interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Immune Responses of the Towne Strain of CMV in Seronegative Women
Status: TERMINATED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: Hepatitis A Vaccine|BIOLOGICAL: Towne CMV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Controlled Active Motion vs Early Passive Mobilization for Flexor Tendons Repair
Status: RECRUITING
Conditions: Flexor Tendon Rupture
Interventions: OTHER: Early passive mobilization|OTHER: Controlled active motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Almorexant in Primary Insomnia
Status: COMPLETED
Conditions: Insomnia|Primary Insomnia
Interventions: DRUG: almorexant|DRUG: almorexant|DRUG: almorexant|DRUG: almorexant|DRUG: almorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparative Effectiveness of Interventions in People With Neck Pain Who Exhibit Directional Preference
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Management according to Mechanical Diagnosis and Therapy|OTHER: Management according to the Cervical Spine Clinical Practice Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circular Economy and the Design of Healthy and Sustainable Food and Ingredients
Status: COMPLETED
Conditions: Overweight|Sustainability|Food|Microbiota|Habits
Interventions: DIETARY_SUPPLEMENT: Dietary recommendations including experimental nutraceutic.|DIETARY_SUPPLEMENT: Dietary recommendations including control nutraceutic.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds
Status: COMPLETED
Conditions: Diabetic Foot Ulcers|Pressure Ulcers
Interventions: DEVICE: HP828-101|DEVICE: Hydrogel/Hydrocolloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Oxytocin on Resting State Neurophysiological Measures
Status: COMPLETED
Conditions: Oxytocin
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Naloxone on the Analgesic Effect of Paracetamol in Healthy Volunteers
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Naloxone and paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-interventional Ambispective Real-world Cohort of rEfractory and reLapsed (R/R) FLT3 Mutated Acute MyEloid Leukemia (AML) Patients Treated With Gilteritinib in FrANCE
Status: COMPLETED
Conditions: Refractory AML|Relapsed Adult AML|FLT3-TKD Mutation|FLT3-ITD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Supine Sleeping After Total Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis|Hip Dislocation
Interventions: BEHAVIORAL: Sleep position: no restrictions|BEHAVIORAL: Sleep position: supine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan
Status: COMPLETED
Conditions: Malaria|Falciparum Malaria|Vivax Malaria
Interventions: DRUG: SP, chloroquine, amodiaquine, primaquine, artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Caspofungin, Liposomal Amphotericin B or the Combination of Both for Patients After Stem-Cell Transplantation
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Fungus Diseases
Interventions: DRUG: caspofungin|DRUG: liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"
Status: UNKNOWN
Conditions: Analgesia|Inguinal Surgery|Undescended Testes|Hydrocele|Torsion Testis|Varicocele|Ilioinguinal Nerve Block
Interventions: PROCEDURE: USG-guided Caudal block|PROCEDURE: USG-guided Ilioinguinal/Iliohypogastric block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis, Biliary
Interventions: DRUG: colchicine|DRUG: methotrexate|DRUG: ursodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Ziconotide Antalgic Efficacy for Severe Refractory Neuropathic
Status: UNKNOWN
Conditions: Severe Refractory Neuropathic Pain|Spinal Cord Lesions
Interventions: DRUG: zicotinide followed by placebo|DRUG: Placebo followed by zicotinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Prescription Opioid Misuse: ROPEs Pilot Trial
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice
Interventions: OTHER: Responsible Opioid Prescriber Education (ROPES)|OTHER: Active Comparator Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Cartagena Cohort Study
Status: ENROLLING_BY_INVITATION
Conditions: Cardiovascular Diseases|COPD|Lung Function Decreased|Atherosclerosis
Interventions: GENETIC: Genetic risk variants|OTHER: Diet|BEHAVIORAL: Physical activity|OTHER: Socio-economic conditions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutrition Intervention and Play Group Exercise for Low-income Latinas
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Home-based nutrition sessions and play group exercise|BEHAVIORAL: Group-based nutrition sessions and mail-out activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Proteins in Head and Neck Cancer Cells
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: Southern blotting|GENETIC: TdT-mediated dUTP nick end labeling assay|GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: flow cytometry|OTHER: fluorescent antibody technique|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03179)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: desloratadine 5 mg|DRUG: fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effects of Etifoxine 100 mg and Lorazepam 2 mg on Vigilance and Cognitive Functions in the Elderly
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: etifoxine|DRUG: lorazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Thumbtack Needle on Ovarian Function of Women With Diminished Ovarian Reserve (DOR)
Status: RECRUITING
Conditions: Diminished Ovarian Reserve
Interventions: OTHER: active thumbtack needle|OTHER: sham thumbtack needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe and placebo|DRUG: Eprotirome and ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Lobular Breast Carcinoma|Breast Carcinoma|Metastatic Breast Cancer|Metastatic Lobular Breast Carcinoma|Metastatic Breast Carcinoma
Interventions: DIAGNOSTIC_TEST: 18F-Fluoroestradiol PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Lower Extremities
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous OCT and B-FAF in Eyes With Alteration of the Foveal Contour
Status: UNKNOWN
Conditions: Lamellar Macular Hole|Lamellar Macular Pseudohole
Interventions: DIAGNOSTIC_TEST: optical coherence tomography and blue-fundus autofluorescence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Robotised Gait Training on Dynamic Balance, Symmetry and Push-off in Persons After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Standard gait training on BART without pelvic perturbations|DEVICE: Robotised gait training with BART with pelvic perturbations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue (MICROBAT)
Status: TERMINATED
Conditions: Pheochromocytoma|Paraganglioma
Interventions: DIAGNOSTIC_TEST: Infrared themrography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Intravenous Ketamine
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Ketamine|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality and Treadmill Training After Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Augmented Reality|BEHAVIORAL: Treadmill training|BEHAVIORAL: Over ground training/standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modafinil in Treating Fatigue in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daily Vitamin D for Sickle-cell Respiratory Complications
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease|Anemia, Sickle Cell|Anemia, Hemolytic, Congenital|Respiratory Tract Diseases|Respiration Disorders|Acute Chest Syndrome|Lung Diseases|Asthma|Respiratory Tract Infections|Nutrition Disorders|Deficiency Diseases Vitamin|Vitamin D Deficiency
Interventions: DRUG: Daily oral vitamin D3, 3,333 IU|DRUG: Bolus oral vitamin D3, 100,000 IU|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Cerebral Vasospasm After Subarachnoid Hemorrhage
Interventions: DRUG: Dantrolene|DRUG: Dantrolene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Accuracy in Measurement of Total Immunoglobulin E Using a Test Device in Atopic Subjects
Status: COMPLETED
Conditions: Atopic Asthma
Interventions: PROCEDURE: Blood sample|DEVICE: POCT device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Dietary Nitrate Ingestion in Heart Failure
Status: SUSPENDED
Conditions: Heart Failure|Heart Failure, Systolic
Interventions: DIETARY_SUPPLEMENT: Nitrate-rich Beetroot Juice|DIETARY_SUPPLEMENT: Nitrate-deplete Beetroot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sickle Cell Disease (SCD) Bone Pain Study
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Low Bone Density|Osteoporosis|Osteopenia|Vertebral Fracture|Vertebral Compression|Osteonecrosis|Ischemic Necrosis|Avascular Necrosis
Interventions: OTHER: Dual-energy X-ray absorptiometry|OTHER: Vertebral fracture analysis|OTHER: Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Milk Fat Intake and Metabolic Health Markers
Status: UNKNOWN
Conditions: Insulin Sensitivity|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Milk Fat|DIETARY_SUPPLEMENT: Control Fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Combined With Computerized Cognitive Addiction Therapy(CCAT) and, Electronic Follow-up for Methamphetamine(MA) Dependent Patients
Status: UNKNOWN
Conditions: Methamphetamine-dependence|Transcranial Direct Current Stimulation|Computerized Cognitive AddictionTherapy|Electronic Health Records
Interventions: DEVICE: Ture Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Laying Open and Sinus Excision of Pilonidal Sinus - a Randomized Study
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Laying open|PROCEDURE: Sinus excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venlafaxine for Depression in Alzheimer's Disease (DIADs-3)
Status: COMPLETED
Conditions: Alzheimer's Disease|Depression
Interventions: DRUG: Placebo|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Progression of HIV-Disease Under Low Dose Corticosteroids
Status: COMPLETED
Conditions: HIV Disease Progression
Interventions: DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Processing.
Status: COMPLETED
Conditions: Cognitive Change|Processing, Visual Spatial
Interventions: BEHAVIORAL: Martial Arts Training Group|BEHAVIORAL: Flexing, Toning and Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: BR101801 in Adult Patients With Advanced Hematologic Malignancies( Phase I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Chronic Lymphocytic Leukemia|Small Lymphocytic Leukemia|B Cell Lymphoma|Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia|Peripheral T Cell Lymphoma
Interventions: DRUG: BR101801 (Phase Ia)|DRUG: BR101801 (Phase Ib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Methadone|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cumulative Live Birth Rates in Patients With Repeated Implantation Failure (RIF) Undergoing Preimplantation Genetic Screening (PGS )
Status: COMPLETED
Conditions: Infertility|Preimplantation Genetic Screening
Interventions: PROCEDURE: PGS (Preimplantation Genetic Screening) with trophectoderm biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of the Addition of Dexmedetomidine to Analgesia for Ankle Surgery.
Status: TERMINATED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small Cell-Lung|Lung Neoplasms|Lung Cancer|Respiratory Tract Neoplasms
Interventions: BIOLOGICAL: AV-299 + gefitinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMS Promotes the Recovery of Patients After Heart Valve Replacement
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: DIETARY_SUPPLEMENT: Probiotic mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Oxygen Enhanced Magnetic Resonance Imaging Method on Patients With Chronic Obstructive Pulmonary Disease During 8 Weeks Treatment With Either Symbicort Turbuhaler or Oxis Turbuhaler
Status: COMPLETED
Conditions: COPD Method Evaluation|Chronic Obstructive Pulmonary Disease Method Evaluation
Interventions: DRUG: Formoterol Turbuhaler|DRUG: Budesonide/Formoterol Turbuhaler|DRUG: Formoterol Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effects of Glycine on Symptoms and Memory in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: Glycine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab Adding on Gemcitabine/S-1 in Metastatic Pancreatic Cancer
Status: UNKNOWN
Conditions: Stage IV Pancreatic Cancer
Interventions: DRUG: Nivolumab|DRUG: Gemcitabine|DRUG: Tegafur-Gimeracil-Oteracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo|DRUG: Asthma therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Technique Assessment of Restylane Silk With Lidocaine for Lip Augmentation
Status: COMPLETED
Conditions: Lip Augmentation and Correction of Perioral Rhytids
Interventions: DEVICE: Restylane Silk with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ureteral Jets on Cystoscopy
Status: COMPLETED
Conditions: Injury of Ureter
Interventions: DRUG: Normal saline|DRUG: Phenazopyridine|DRUG: Dextrose 10%|DRUG: Sodium Fluorescein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effectiveness of CelluTome Epidermal Harvesting System in Autologous Skin Grafting of Chronic Wound Patients
Status: WITHDRAWN
Conditions: Wounds and Injuries
Interventions: DEVICE: Cellutome Epidermal Harvesting System|PROCEDURE: Split Thickness Skin Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Incontinence After Radical Prostatectomy
Status: RECRUITING
Conditions: Incontinence, Urinary|Radical Prostatectomy
Interventions: OTHER: Transperinal ultrasound guided instruction in pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Intra-lesional Bleomycin Versus Intra-lesional Purified Protein Derivative in Treatment of Palmoplantar Warts
Status: UNKNOWN
Conditions: Warts
Interventions: DRUG: Bleomycin|DRUG: Purified Protein Derivative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pursestring Wound Closure vs "Gunsight" Skin Incision and Closure Technique to Reverse Stoma
Status: COMPLETED
Conditions: Colostomy
Interventions: PROCEDURE: Pursestring Wound Closure|PROCEDURE: Gunsight Skin Incision and Closure Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis
Status: COMPLETED
Conditions: Halitosis
Interventions: OTHER: Experimental Dentifrice|OTHER: Reference Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Heat Wash-out (HWO) in 4 Groups of Women (Pre- and Postmenopausal With and Without Female Sexual Arousal Disorder (FSAD)).
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological
Interventions: DEVICE: Vaginal Heat Wash-Out Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Can GnRH Agonist Trigger Prevent Ovarian Hyperstimulation Syndrome?
Status: TERMINATED
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Triptorelin 0.2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer
Status: COMPLETED
Conditions: Major Depressive Disorder|Neoplasms
Interventions: DRUG: Mirtazapine|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Examining the Impact of Blood Flow Restricted Aerobic Exercise on PGC-1α mRNA Expression in Young Healthy Males
Status: COMPLETED
Conditions: Mitochondrial Biogenesis
Interventions: OTHER: BFR Exercise|OTHER: CTL Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SC0191 Plus Chemotherapy in Advanced Ovarian Canceradvanced Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Serous Ovarian Cancer|Advanced Ovarian Cancer
Interventions: DRUG: SC0191|DRUG: Gemcitabine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Controlled Trial of Apremilast for Rheumatoid Arthritis Treatment (CARAT)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: apremilast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Rumex Acetosa L on the Intraoral Colonization With Porphyromonas Gingivalis
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: Rumex acetosa L. extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML
Status: COMPLETED
Conditions: Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Gene Abnormality|Cytogenetic Abnormality
Interventions: DRUG: VAH regimen|DRUG: VEN+HMA regimen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: risankizumab IV|DRUG: placebo for risankizumab|DRUG: risankizumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Tolvaptan Tablet to Treat Cirrhosis Ascites
Status: COMPLETED
Conditions: Ascites|Hepatic Cirrhosis
Interventions: DRUG: Tolvaptan|DRUG: Tolvaptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Model for Cardiac Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Disease|Arteriosclerosis|Cardiovascular Diseases
Interventions: BEHAVIORAL: educational model + follow up|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mesenchymal Stem Cells for Multiple Organ Dysfuntion Syndrome After Surgical Repaire of Acute Type A Aortic Dissection
Status: UNKNOWN
Conditions: Multiple Organ Dysfunction Syndrome
Interventions: BIOLOGICAL: MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estrogen Receptor Beta Agonists (Eviendep) and Polyp Recurrence
Status: COMPLETED
Conditions: Adenocarcinoma of Colon Recurrent
Interventions: DIETARY_SUPPLEMENT: Eviendep (CM&D Pharma Limited, UK)|DIETARY_SUPPLEMENT: Maltodextrins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Signalling in Muscle- and Adipose-tissue Following Insulin Withdrawal and Growth Hormone Injection.
Status: COMPLETED
Conditions: Diabetes Mellitus Type I|Ketoacidosis
Interventions: DRUG: Insulin withdrawal|DRUG: Norditropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Efficacy of Lidocaine Plus Bupivacaine Versus Bupivacaine Alone Caudally
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: 0.5 ml.kg-1 bupivacaine 0.25%|DRUG: 0.5 ml.kg-1 bupivacaine 0.25% with the addition of 3 mg/kg lidocaine 1%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Manuka Honey Eye Drops VS Conventional Treatment of Meibomian Gland Dysfunction Related Dry Eye Disease
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: manuka honey 16% eye drops ( Optimel )|DEVICE: systane eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Arterial Revascularization (TAR)
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Artery Bypass Grafting
Interventions: PROCEDURE: Y-Graft|PROCEDURE: In-Situ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery
Status: RECRUITING
Conditions: Inguinal Surgery
Interventions: DRUG: Ibuprofen|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Tucidinostat in Combination With R-CHOP in Patients With Newly Diagnosed Double-Expressor DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: R-CHOP(Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone)|DRUG: Tucidinostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection
Status: RECRUITING
Conditions: Adenoma|Colorectal Cancer|Colorectal Neoplasms
Interventions: DEVICE: ENDOCUFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: SK-1403 Long-term Treatment Study; Long-term Study in Patients With Secondary Hyperparathyroidism Receiving Hemodialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: SK-1403
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD)
Status: COMPLETED
Conditions: Any Single Gene Disorder (Cystic Fibrosis, Tay-Sachs)
Interventions: OTHER: preimplantation diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 131I-MIBG With Myeloablative Chemotherapy and Autologous Stem Cell Transplantation for the Treatment of High-risk Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: 131I-MIBG , Etoposide, Melphalan, Carboplatin, Autologous Peripheral Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLN518 in Combination With Standard Induction Chemo. for Treatment of Patients With Newly Diagnosed Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: MLN518
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bemiparin as a Thromboprophylaxis After Gynaecological Surgeries
Status: COMPLETED
Conditions: Deep Vein Thrombosis (DVT)|Pulmonary Embolism
Interventions: DRUG: Bemiparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION