pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cinrebafusp Alfa in Combination With Ramucirumab and Paclitaxel in HER2-High Gastric or GEJ Adenocarcinoma and in Combination With Tucatinib in HER2-Low Gastric or GEJ Andenocarinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Gastric Cancer
Interventions: DRUG: Cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel|DRUG: Cinrebafusp alfa (PRS-343) in combination with tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Effect of Removal of Porphyromonas Gingivalis on Prognosis of Esophageal Cancer After Radical Surgery
Status: NOT_YET_RECRUITING
Conditions: Evaluate the DFS of Patients With Esophageal Cancer Who Underwent Radical Operation After Regular Removal of Porphyromonas Gingivalis
Interventions: COMBINATION_PRODUCT: Tinidazole oral microneedle patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interindividual Variation in Response to Green Coffee
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Green coffee|DIETARY_SUPPLEMENT: Roasted coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Minimally Invasive Prostatic Vapor Ablation for the Treatment of BPH in Large Prostates (Rezūm XL)
Status: TERMINATED
Conditions: BPH With Urinary Obstruction|BPH|BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Interventions: DEVICE: Prostatic Vapor Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Extension Study of Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: HEADWAY-DLB Extension
Status: TERMINATED
Conditions: Dementia With Lewy Bodies
Interventions: DRUG: RVT-101 35 mg|DRUG: RVT-101 70 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effect of Targeted Intrinsic Foot Muscles Exercises in Plantar Fasciitis
Status: UNKNOWN
Conditions: Plantar Fasciitis, Chronic|Pain
Interventions: OTHER: targeted intrinsic foot muscle exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Trial of TS-1 and Oxaliplatin in Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: TS-1, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is it Safe to do Laparoscopic Cholecystectomy for Acute Cholecystitis up to Seven Days?
Status: COMPLETED
Conditions: Acute Cholecystitis
Interventions: PROCEDURE: Early laparoscopic cholecystectomy|PROCEDURE: Late laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Active Mobilization of Hamstring for Non-specific Low Back Pain and Musculoskeletal Discomfort During Prolonged Sitting
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Active hamstring flexibility exercises with hip flexion mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women
Status: RECRUITING
Conditions: Pregnancy|Weight Gain
Interventions: BEHAVIORAL: Grocery delivery|BEHAVIORAL: Unsweetened beverage delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study to Evaluate Efalizumab in Combination With UVB for Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Efalizumab|DEVICE: Narrow Band Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Responses and Safety of Recombinant Human CD40 Ligand in Patients With X-Linked Hyper-IgM Syndrome
Status: COMPLETED
Conditions: Immunoproliferative Disorder
Interventions: DRUG: Bacteriophage|DRUG: rhuCD40L|DRUG: KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Liposome Serrate Anterior Plane Block vs Traditional Thoracic Paravertebral Block
Status: COMPLETED
Conditions: Lung Cancer
Interventions: COMBINATION_PRODUCT: Bupivacaine Liposome SAPB|COMBINATION_PRODUCT: Traditional TPVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lucanthone to Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Brain Metastases|Non-small Cell Lung Cancer
Interventions: DRUG: Lucanthone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide
Status: UNKNOWN
Conditions: Chemotherapeutic Agent Toxicity|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: GENETIC: gene expression analysis|GENETIC: polymorphism analysis|PROCEDURE: management of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Group B Streptococcus Vaccine in Healthy Females
Status: COMPLETED
Conditions: Group B Strep Infection
Interventions: BIOLOGICAL: GBS-NN/NN2 with Alhydrogel® 25|BIOLOGICAL: Placebo GBS-NN/NN2 with Alhydrogel® 25|BIOLOGICAL: Placebo GBS-NN/NN2 with Alhydrogel® 50|BIOLOGICAL: GBS-NN/NN2 with Alhydrogel® 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PVDF (DynaMesh®-SIS Soft) Retropubic Midurethral Slings in Stress Urinary Incontinence in Women
Status: COMPLETED
Conditions: Urinary Stress Incontinence|Urinary Incontinence,Stress
Interventions: OTHER: 24 month follow up of women with validated questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bromelain, Comosain as a New Drug for Treating and Preventing Various Types of Cancer in the Humans
Status: UNKNOWN
Conditions: Cancer
Interventions: BIOLOGICAL: Bromelain and Comosain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Dose Titration And Dose Tapering On The Tolerability Of DVS SR In Women With Vasomotor Symptoms
Status: COMPLETED
Conditions: Vasomotor Symptoms
Interventions: DRUG: desvenlafaxine succinate sustained release|DRUG: desvenlafaxine succinate sustained release|DRUG: desvenlafaxine succinate sustained release|DRUG: desvenlafaxine succinate sustained release|DRUG: Placebo|DRUG: desvenlafaxine succinate sustained release|DRUG: desvenlafaxine succinate sustained release|DRUG: desvenlafaxine succinate sustained release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Children Education and Cardiovascular Risk Reduction in Their Parents
Status: COMPLETED
Conditions: Risk Reduction
Interventions: BEHAVIORAL: Educational program in cardiovascular prevention|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Accuracy of Synovial Biopsy for Implant-Related Shoulder Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Shoulder Arthroplasty
Interventions: DIAGNOSTIC_TEST: Synovial Biopsy|DIAGNOSTIC_TEST: Open Tissue Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Efficacy of Ribociclib After Progression on CDK4/6 Inhibition in Patients With HR+ HER2- Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Breast Carcinoma
Interventions: DRUG: LEE-011|DRUG: Fulvestrant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subjects With Clinical Diagnosis of Allergic Rhinitis Were Randomly Divided Into 2 Groups, With Patients in One Group Given One Treatment Session of Red Light Rhinophototherapy, Followed by Medical Treatment. Those in the Second Group Were Treated With Medical Treatment Only.
Status: COMPLETED
Conditions: Allergic Rhinitis|Phototherapy
Interventions: DEVICE: Transverse Many Channels Laser Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PFx Closure System in Subjects With Cryptogenic Stroke, TIA, Migraine or Decompression Illness
Status: SUSPENDED
Conditions: PFO|Stroke|Transient Ischemic Attack|Migraine|Decompression Illness
Interventions: DEVICE: PFx Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Early Complementary Feeding on Growth, Neurodevelopment, Sleep and Gut Health
Status: RECRUITING
Conditions: Linear Growth|Neurodevelopment|Gut Microbiome
Interventions: OTHER: Baby Foods|OTHER: Foods from the home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine (NAC)|DIETARY_SUPPLEMENT: Placebo|PROCEDURE: Positive Airway Pressure (PAP) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Understanding Pine Bark Extract as an Alternative Treatment (UPBEAT) Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Pine Bark Extract (Flavangenol®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Nivolumab in Selected Uterine Cancer Patients
Status: COMPLETED
Conditions: Uterine Cancer|Endometrial Carcinoma|Carcinosarcoma|Leiomyosarcoma|Undifferentiated Sarcoma|High Grade Endometrial Stromal Sarcoma|Clear Cell Carcinoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiogenesis Inhibitor Plus Anti-PD-1/PD-L1 Antibody in Advanced Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Neoplasms
Interventions: DRUG: an anti-PD-1/PD-L1 antibody plus an angiogenesis inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Excellent BRASSS-V Drape™ Versus Indirect Measurement Protocol for Measurement of Postpartum Blood Loss
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DEVICE: Excellent BRASSS-V Drape™.|OTHER: Indirect weight assesment of blood loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Yoga and Aerobic Exercise Effects on Cognition
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Sun salutations|BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Seated rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Reduce Diaper Need and Increase Use of Pediatric Preventive Care
Status: COMPLETED
Conditions: Diaper Dermatitis|Urinary Tract Infections|Infection|Depressive Symptoms|Stress
Interventions: OTHER: Diaper Incentive|OTHER: Conditional Cash Transfer Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of XL647 in Subjects With NSCLC Who Have Progressed After Responding to Treatment With Gefitinib or Erlotinib
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: XL647
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA
Status: TERMINATED
Conditions: Granulomatosis With Polyangiitis (GPA)|Microscopic Polyangiitis (MPA)
Interventions: DRUG: IFX-1 low dose|DRUG: IFX-1 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone and Insulin Growth Factor 1 Deficiencies in Children/Adolescents Following Traumatic Brain Injury: The Impact on Growth and Neuropsychological Development
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Growth Hormone Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration
Status: COMPLETED
Conditions: Ranitidine Adverse Reaction|Pharmacokinetics|Food-drug Interaction
Interventions: DRUG: Ranitidine|DRUG: Placebo|OTHER: Low nitrite/NDMA meals|OTHER: High nitrite/NDMA meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|CLL|Progressive Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Relapsed Chronic Lymphocytic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being
Status: COMPLETED
Conditions: Depressive Symptoms|Stress, Psychological
Interventions: BEHAVIORAL: mPEP|BEHAVIORAL: Bibliotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Remote Patient Monitoring Solution for Chronic Respiratory Disease Management
Status: NOT_YET_RECRUITING
Conditions: Asthma|Asthma Attack|Asthma in Children|Asthma Acute|Asthma Chronic
Interventions: DEVICE: AeviceMD device|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Solid Tumor
Interventions: DRUG: JZP815
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-Part Study to Evaluate the Dose Response of SCH 527123 on Sputum Neutrophilia Following Ozone Challenge in Healthy Subjects and Chronic Obstructive Pulmonary Disease (COPD) Patients (P05567 AM7)
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: SCH 527123|DRUG: SCH 527123|DRUG: SCH 527123|DRUG: SCH 527123|DRUG: Placebo|DRUG: SCH 527123|DRUG: SCH 527123|DRUG: SCH 527123|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Randomized Phase III Study Comparing Maintenance Treatment With Fluoropyrimidine + Bevacizumab Versus Fluoropyrimidine After Induction Chemotherapy for a Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fluoropyrimidine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)
Status: RECRUITING
Conditions: NonSegmental Vitiligo
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I-B Study to Evaluate the Safety, Tolerability and Efficacy of IZN-6NVS for the Treatment of AV and DIV
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DRUG: IZN-6NVS Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Graft-Versus-Host Disease|Engraftment Syndrome
Interventions: DRUG: Pentostatin|DRUG: Sirolimus|DRUG: Cyclophosphamide|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplant (HSCT)|PROCEDURE: Th2 rapa cells|PROCEDURE: Donor Lymphocyte Harvest|PROCEDURE: Induction Therapy|PROCEDURE: GVHD prophylaxis|PROCEDURE: Donor Hematopoietic Stem Cell Harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Antimicrobial Prescribing Practices in the Neonatal ICU
Status: COMPLETED
Conditions: Infants in Neonatal Intensive Care Units
Interventions: OTHER: Education Plus (E+)|OTHER: Clinical Decision Support|OTHER: Prescriber Audit and Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Korean Multicenter Prospective Registry of In.PACT DEB for Isolated Popliteal Artery Disease (K-POP Study)
Status: UNKNOWN
Conditions: Popliteal Artery Disease
Interventions: DEVICE: drug-eluting balloon (In.PACT Admiral, Medtronic)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tractography and Diffusion Tensor Imaging of the Human Spinal Cord in Healthy Subjects : Anatomical Atlas
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: PROCEDURE: Spinal cord Tractography in order to differentiate spinal tracts.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol
Status: COMPLETED
Conditions: Intercritical Gout
Interventions: DRUG: Colchicine (Colcrys®)|DRUG: placebo|DRUG: allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID.
Status: TERMINATED
Conditions: Parkinson's Disease|Levodopa Induced Dyskinesias (LID)
Interventions: DRUG: 240mg Amantadine HCl ER tablets|DRUG: Placebo tablets|DRUG: 320mg Amantadine HCl ER tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plantar Pressures After Pressure Release of the Flexor Digitorum Brevis Muscle Versus a Non-emission Laser.
Status: COMPLETED
Conditions: Manual Therapy|Myofascial Pain Syndrome|Foot|Flat Foot
Interventions: OTHER: Pressure release|OTHER: Non emision Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease
Status: UNKNOWN
Conditions: Diabetes Mellitus|Ischemic Heart Disease|Multi Vessel Coronary Artery Disease
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: MDS|AML
Interventions: DRUG: ASTX727|OTHER: Donor Lymphocyte Infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DEVICE: Directional Brachytherapy Source Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Testicular Tissue Transplantation
Status: RECRUITING
Conditions: Cancer|Sickle Cell Thalassemia|Hematologic Diseases
Interventions: PROCEDURE: Autologous testicular tissue transplantation of prepubertal frozen testicular tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mg
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Heart Disease|Atherosclerosis
Interventions: DRUG: Rosuvastatin|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Folate Status of a General Population(FOLSUPP STUDY)
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Folic acid (supplement)|DIETARY_SUPPLEMENT: Metafolin (supplement)|DRUG: Placebo|OTHER: Folate rich foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Development and Validation of a Deep Learning Algorithm for Bowel Preparation Quality Scoring
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DEVICE: Artificial intelligence assisted bowel preparation quality scoring system|DEVICE: Conventional human scoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: pegaspargase|DRUG: thioguanine|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vasopressors on Cerebral Oxygentaion During Off Pump CABG
Status: COMPLETED
Conditions: Cerebral Oxygen Saturation
Interventions: DRUG: Phenylephrine|DRUG: Norepinephrine|DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saline-induced Distal to Aortic Coronary Pressure Ratio vs. Resting and Hyperemic Indices of Coronary Artery Stenosis Severity
Status: COMPLETED
Conditions: Coronary Stenosis
Interventions: PROCEDURE: Saline Pd/Pa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: In Vivo Analysis of Muscle Stem Cells in Chronic and Acute Lower Limb Ischemia (MyostemIschemia)
Status: UNKNOWN
Conditions: Artery Disease|Muscle Disorder
Interventions: PROCEDURE: Gastrocnemius muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TP-0903 for the Treatment of FLT3 Mutated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Dubermatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol for Reduction of Blood Loss During Fibroid Surgery
Status: TERMINATED
Conditions: Fibroids
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Trichosanthes Root on Blood Sugar in Patients With Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Trichosanthes root|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Failed Insertion of Ureteral Access Sheath During Flexible Ureterorenoscopy
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: PROCEDURE: Flexible Ureterorenoscopy|PROCEDURE: Mini Percutaneous Nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety,Efficacy and Pharmacokinetics of CT-1530 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia
Status: UNKNOWN
Conditions: Relapsed or Refractory B Cell Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Waldenstrom's Macroglobulinemia|Mantle Zone Lymphoma Refractory/Recurrent|Follicle Centre Lymphoma Diffuse|Diffuse Large B Cell Lymphoma
Interventions: DRUG: CT-1530
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Radial Fractures in Adult Patients: 4 Weeks Versus 6 Weeks of Cast Immobilisation Following Closed Reduction.
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Below Elbow cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Therapy for Lymph Nodes in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Photon|RADIATION: 3D-Proton/Conventional plan or 3D-proton only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Safe BAY3283142 is When Taken as a Single Dose or as Multiple Doses in Healthy Chinese Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease|Non-proliferative Diabetic Retinopathy|Healthy Volunteers
Interventions: DRUG: BAY3283142|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of VSJ-110 in the Treatment of Allergic Conjunctivitis in Adults With a History of Ocular Allergies
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: VSJ-110|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Safety and Efficacy Study of VI-0521 in Adolescents With Obesity
Status: COMPLETED
Conditions: Adolescent Obesity|Obesity in Adolescence|Adolescent Overweight
Interventions: DRUG: VI-0521 oral capsule|DRUG: Placebo oral capsule|BEHAVIORAL: Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Stage III Melanoma|Stage IV Melanoma
Interventions: DRUG: Nivolumab + Ipilimumab|DRUG: Encorafenib + Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib (BMS-354825) in Patients With Advanced Estrogen/Progesterone Receptor-positive (ER+/PR+) or Her2/Neu-positive (Her2/Neu+)Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastasis
Interventions: DRUG: Dasatinib|DRUG: Dasatinib 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP vs HA Intra-articular Injections in TMDs
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Pain
Interventions: PROCEDURE: Hyaluronic acid (HA) injection|PROCEDURE: Platelet-rich plasma (PRP) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Probiotics for the Treatment and Prevention of Vulvovaginal Infections in Pregnancy - Double-blind, Randomized, Placebo-controlled Study
Status: COMPLETED
Conditions: Bacterial Vaginosis and Vaginal Candidiasis at Pregnancy
Interventions: DIETARY_SUPPLEMENT: Probiotic Capsule containing L. acidophilus, L. Paracasei, L. Rhamnosus, streptococcus thermophilus and Bifidobacterium bifidum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stop and go Strategy as First-line Treatment for Widely Metastatic Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Metastatic Nasopharyngeal Carcinoma|Intermittent Systematic Chemotherapy
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Paclitaxel protein-bound|DRUG: Capecitabine|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Rivaroxaban 20 mg Film-coated Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivaroxaban 20 mg film-coated tablet|DRUG: Xarelto 20 mg film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Split-dose Versus Single-dose Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Colonic Cancer|Colonic Polyp|IBS - Irritable Bowel Syndrome
Interventions: PROCEDURE: Bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Duloxetine in Patients With Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis Knee Pain
Interventions: DRUG: Duloxetine (DLX)|DRUG: Placebo (PLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat Heartburn
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Dexlansoprazole MR|DRUG: Dexlansoprazole MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Chemotherapy Regimens in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery
Status: RECRUITING
Conditions: Erection; Incomplete
Interventions: DRUG: General Anesthesia: Propofol|DRUG: General Anesthesia: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Basal Cell Carcinomas Treated With Ablative Fractional Laser and Ingenol Mebutate
Status: COMPLETED
Conditions: Carcinoma, Basal Cell
Interventions: DRUG: AFXl-assisted ingenol mebutate delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Gas-Filled Intragastric Balloons or Endoscopic Sleeve Gastroplasty Affect Hunger, Hunger Hormones, and Gastric Emptying Compared to Meal Replacements
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: GF-IGB: Obalon Balloon|DIETARY_SUPPLEMENT: Medically Supervised Meal Replacement Program: My New Weigh|PROCEDURE: Endoscopic sleeve gastroplasty: (ESG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer.
Status: RECRUITING
Conditions: Thyroid Cancer, Medullary|Neuroendocrine Tumor of the Lung Grade 1 and 2|Neuroendocrine Tumor of the Thymus Grade 1 and 2|Neuroendocrine Tumor GEP Grade 1-3
Interventions: DRUG: 177Lu-PP-F11N
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Gemcitabine in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Cancer
Interventions: DRUG: gemcitabine, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the BTL-899 Therapy for Non-invasive Lipolysis and Circumference Reduction of Abdomen When Compared to a Sham Treatment
Status: UNKNOWN
Conditions: Improvement of Abdomen Appearance
Interventions: DEVICE: BTL-899|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Enteric Nervous System in Spinal Cord Injury: Study of the Enteric Nervous System and the Intestinal Epithelial Barrier Via Colonic Biopsies in Spinal Cord Injury Patients
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Haplo-PBSC+Cord vs Haplo-PBSC+BM for Hematological Malignancies Undergoing Allo-HSCT
Status: COMPLETED
Conditions: Hematological Malignancies|Hematopoietic Stem Cell Transplantation
Interventions: OTHER: PBSCs|OTHER: Cord|OTHER: BMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Garston Tool and Neuromuscular Reeducation in Cervical Headache
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: DEVICE: Garston tool|PROCEDURE: Neuromuscular Re-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Continuous and Pulse Mode of Ultrasound Therapy in Myalgia of Maxillofacial Region
Status: COMPLETED
Conditions: Myalgia|Trigger Point
Interventions: DEVICE: therapeutic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab-based Maintenance in Patients With RAS Wild-type, Metastatic Colorectal Cancer (Valentino)
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: 5-fluorouracil,leucovorin,panitumumab|DRUG: panitumumab|DRUG: Oxaliplatin, 5-fluorouracil,leucovorin,panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Transplant Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Cytomegalovirus
Interventions: BIOLOGICAL: CMV-pp65 CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
Status: NOT_YET_RECRUITING
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Standard smoking cessation program (SCP)|BEHAVIORAL: Cognitive remediation treatment (CRT)|BEHAVIORAL: High-intensity interval training (HIIT evening)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Clomifen, Ethinyl Estradiol|DRUG: Menotropins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Methoxy Polyethylene Glycol Epoetin Beta Daily Use in Participants on Peritoneal Dialysis
Status: COMPLETED
Conditions: Renal Impairment|Renal Anemia of Chronic Kidney Disease
Interventions: DRUG: Methoxy polyethylene glycol epoetin beta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cadonilimab+ Paclitaxel (Albumin-bound) Treat Advanced Gastric Adenocarcinoma With PD-(L)1 Inhibitors Resistance
Status: NOT_YET_RECRUITING
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: cadonilimab combined +paclitaxel (albumin-bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis B
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: CB06-036|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School-Based Program On Metabolic Disease
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Cardiovascular Function|Kidney Diseases|Liver Diseases|Physical Fitness
Interventions: BEHAVIORAL: Health Education and Physical activity program|DIETARY_SUPPLEMENT: Nutrition Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluoroscopic Guided Interlaminar Epidural Versus Ultrasound Guided Transforaminal Epidural in the Treatment of Unilateral Cervicobrachialgia.
Status: UNKNOWN
Conditions: Cervicobrachial Neuralgia
Interventions: OTHER: Ultrasound-guided transforaminal epidural steroid injection|OTHER: Interlaminar epidural steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial
Status: RECRUITING
Conditions: Rheumatic Heart Disease
Interventions: DRUG: phenoxymethyl penicillin|DRUG: intramuscular benzathine penicillin G (BPG) prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
Status: RECRUITING
Conditions: Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Head and Neck Carcinoma of Unknown Primary|Locally Advanced Head and Neck Squamous Cell Carcinoma|Locally Advanced Hypopharyngeal Squamous Cell Carcinoma|Locally Advanced Laryngeal Squamous Cell Carcinoma|Locally Advanced Nasal Cavity Squamous Cell Carcinoma|Locally Advanced Oral Cavity Squamous Cell Carcinoma|Locally Advanced Oropharyngeal Squamous Cell Carcinoma|Locally Advanced Paranasal Sinus Squamous Cell Carcinoma|Locally Advanced Sinonasal Squamous Cell Carcinoma|Maxillary Sinus Squamous Cell Carcinoma|Stage III Hypopharyngeal Carcinoma AJCC v8|Stage III Laryngeal Cancer AJCC v8|Stage III Lip and Oral Cavity Cancer AJCC v8|Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage III Sinonasal Cancer AJCC v8|Stage IVA Hypopharyngeal Carcinoma AJCC v8|Stage IVA Laryngeal Cancer AJCC v8|Stage IVA Lip and Oral Cavity Cancer AJCC v8|Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IVA Sinonasal Cancer AJCC v8|Stage IVB Hypopharyngeal Carcinoma AJCC v8|Stage IVB Laryngeal Cancer AJCC v8|Stage IVB Lip and Oral Cavity Cancer AJCC v8|Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IVB Sinonasal Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Ipatasertib|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of SE-TAP, M-TAPA, and Rectus Sheath Block in Abdominal Surgeries
Status: ENROLLING_BY_INVITATION
Conditions: Postoperative Pain
Interventions: PROCEDURE: Bilateral SE-TAP|PROCEDURE: Bilateral M-TAPA|PROCEDURE: Bilateral RSB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: estramustine phosphate sodium|DRUG: exisulind
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: ulipristal acetate|DRUG: placebo|DRUG: ulipristal acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Almonertinib Treats Advanced NSCLC Patients With EGFR Mutations Who Are Safety Intolerant After Osimertinib Treatment
Status: UNKNOWN
Conditions: Lung Cancer|EGFR Gene Mutation
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pimecrolimus Ophthalmic Suspension in Patients With Moderate to Severe Keratoconjunctivitis Sicca
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: Pimecrolimus|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Entrectinib|DRUG: Entrectinib|DRUG: Alectinib|DRUG: Atezolizumab|DRUG: Ipatasertib|DRUG: Trastuzumab emtansine|DRUG: Idasanutlin|DRUG: Inavolisib|DRUG: Belvarafenib|DRUG: Pralsetinib|DRUG: GDC-6036|DRUG: Camonsertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Efficacy of New Probiotic Strains in Health Adults
Status: UNKNOWN
Conditions: Gastrointestinal Health|Respiratory Health|Safety
Interventions: DIETARY_SUPPLEMENT: Cocktail|DIETARY_SUPPLEMENT: CGI314|DIETARY_SUPPLEMENT: CSI08|DIETARY_SUPPLEMENT: MIT411
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE