pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Islet Cell Transplantation Alone and CD34+ Enriched Bone Marrow Cell Infusion in Patients With Diabetes Mellitus: Steroid-Free Regimen
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: Islet Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of the Technology-based Cardiac Rehabilitation Program in Coronary Artery Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Physical Inactivity
Interventions: OTHER: Physiotherapist supervised exercise training|OTHER: Exercise training via phone app|OTHER: Physical activity recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Mind-body Education Program to Enhance Resiliency and Reduce Burnout in Residents
Status: UNKNOWN
Conditions: Resident Burnout
Interventions: BEHAVIORAL: Stress Management and Resiliency Training for Residents (SMART-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
Status: RECRUITING
Conditions: Dermatologic Disease
Interventions: DRUG: Tacrolimus ointment|DRUG: Hydrocortisone 1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Chemoprophylaxis Against Travelers' Diarrhea - Prevent TD
Status: COMPLETED
Conditions: Travelers' Diarrhea|Functional Bowel Disorders|Reactive Arthritis
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium Chewable Tablets 5mg Under Fasted Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Montelukast Sodium Chewable Tablets 5mg|DRUG: Singulair® (Montelukast Sodium) Chewable Tablets 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Treatment of NF1-related Plexiform Neurofibroma With Trametinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1|Child|Neurofibroma, Plexiform
Interventions: DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: ATG|DRUG: fludarabine|DRUG: cyclophosphamide|RADIATION: Total body irradiation|PROCEDURE: Stem cell infusion|DRUG: Sirolimus|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting
Status: RECRUITING
Conditions: Acute Bilineal Leukemia|Acute Biphenotypic Leukemia|Acute Myeloid Leukemia|Mixed Phenotype Acute Leukemia|T Acute Lymphoblastic Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acthar for the Treatment of Systemic Lupus Erythematosus (SLE) in Patients With a History of Persistently Active Disease
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Acthar|DRUG: Placebo|DRUG: Steroid Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: HR070803 plus oxaliplatin, 5-FU/LV, bevacizumab|DRUG: HR070803 simulator plus oxaliplatin, 5-FU/LV, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cholinergic and Cognitive Function Using Pharmacologic ASL-Perfusion MRI
Status: COMPLETED
Conditions: Cholinergic Function
Interventions: DRUG: Scopolamine|DRUG: Placebo|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study of the Safety and Effectiveness of Two Doses of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixazomib, Thalidomide and Dexamethasone in Newly Diagnosed and Treatment-naive Multiple Myeloma (MM) Participants Non-eligible for Autologous Stem-cell Transplantation
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cycloplegic Refraction Among Children
Status: COMPLETED
Conditions: Cycloplegia
Interventions: DRUG: Cyclopentolate|DRUG: Tropicamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Pharmacokinetics, Efficacy and Safety of Balugrastim in Pediatric Patients With Solid Tumors
Status: WITHDRAWN
Conditions: Solid Tumors
Interventions: DRUG: Balugrastim|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveying Parents About Genome Screening of Newborns
Status: UNKNOWN
Conditions: Parents of Healthy Newborns
Interventions: OTHER: Genetics education at baseline|OTHER: Hypothetical genomic scenarios at follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Seralutinib|DEVICE: Gereic Dry Powder Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure (GB30) on Ventrogluteal Intramuscular Injection Pain
Status: COMPLETED
Conditions: Acute Pain|Injection|Needle Phobia
Interventions: PROCEDURE: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis
Status: RECRUITING
Conditions: Patients With Candidemia and/or Invasive Candidiasis
Interventions: DRUG: HRS9432|DRUG: Caspofungin Acetate for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Ozone Application in Stepwise Excavation Procedure of Primary Molars With Deep Carious Lesion
Status: COMPLETED
Conditions: Deep Caries|Ozone
Interventions: OTHER: ozone|OTHER: chlorhexidine digluconate|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth
Status: WITHDRAWN
Conditions: Neonatal Sepsis|Neonatal Mortality Rate
Interventions: DRUG: 0.25% chlorhexidine|DRUG: sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TCD601 in de Novo Renal Transplant Recipients
Status: RECRUITING
Conditions: Renal Transplantation
Interventions: BIOLOGICAL: TCD601|BIOLOGICAL: belatacept|DRUG: ATG|DRUG: TAC|DRUG: MPA|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial to Improve Safe Firearm Storage
Status: COMPLETED
Conditions: Firearm Injury|Pediatric Emergency Medicine|Suicide and Self-harm|Mental Health Issue
Interventions: BEHAVIORAL: Lethal means counseling|BEHAVIORAL: Provision of Cable-style gun locks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pharmaceutical Consultations Just Before Rheumatology Consultations on Improving Knowledge and Skills for Patients With Inflammatory Arthritis With Subcutaneous Biologic DMARDs
Status: UNKNOWN
Conditions: Arthritis, Rheumatoid|Spondyloarthritis|Biological Therapy
Interventions: OTHER: Pharmacist's consultation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attachment-Based Family Therapy for Adolescents With Binge Eating
Status: UNKNOWN
Conditions: Bulimia Nervosa|Binge-Eating Disorder|Other Specified Feeding or Eating Disorder
Interventions: BEHAVIORAL: Attachment-Based Family Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions
Status: RECRUITING
Conditions: Percutaneous Coronary Intervention|Platelet Aggregation Inhibitors|Coronary Artery Disease
Interventions: OTHER: Algorithm-guided DAPT duration|OTHER: Standard-of-care DAPT duration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Trial to Evaluate the Effects of a Novel Renal Multivitamin on Inflammation and Other Biomarkers in Endstage Renal Disease Patients
Status: UNKNOWN
Conditions: Hyperphosphatemia|Inflammation|Renal Disease
Interventions: DIETARY_SUPPLEMENT: Oral Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride and Irinotecan Hydrochloride in Treating Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Solid Neoplasm
Interventions: DRUG: Erlotinib Hydrochloride|DRUG: Irinotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRagmatic Analysis of Vitamin D in ANCA-Associated Vasculitis
Status: COMPLETED
Conditions: ANCA-associated Vasculitis|Granulomatosis With Polyangiitis|Microscopic Polyangiitis|Eosinophilic Granulomatosis With Polyangiitis
Interventions: DIETARY_SUPPLEMENT: vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED
Status: TERMINATED
Conditions: Acute Pain|Opioid Use
Interventions: DRUG: low dose ketamine|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding
Status: COMPLETED
Conditions: Peptic Ulcers|Upper Gastrointestinal Bleeding
Interventions: DRUG: omeprazole|DRUG: pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Integrated Learning Support System Based on Immersive Simulated Training for Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Simulation Training|Learning|Educational Technology|Nephrotoxicity|Physiological Stress
Interventions: OTHER: Integrated Learning Support System|OTHER: Standard Learning Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications
Status: COMPLETED
Conditions: Anesthesia|Pulmonary Atelectasis|Complication of Anesthesia
Interventions: OTHER: Open lung extubation|OTHER: Conventional extubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Subcutaneous RoActemra/Actemra (Tocilizumab) as Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: DMARD|DRUG: methotrexate|DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it
Status: COMPLETED
Conditions: Pain|Neuropathic Pain|Chronic Pain|Visceral Pain
Interventions: DRUG: GRTA9906 60 mg PR tablet|DRUG: GRTA9906 60 mg IR capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of DEB-TACE Performed With a Novel Reflux-control Microcatheter in Patients With HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: COMBINATION_PRODUCT: Chemoembolization with preloaded microparticles 100 micron and reflux control microcatheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuro- and Biofeedback in Nonsuicidal Self-injury
Status: RECRUITING
Conditions: Nonsuicidal Self Injury|Emotion Regulation
Interventions: OTHER: Real-time functional magnetic resonance imaging Neurofeedback and Real-time Biofeedback|OTHER: Sham functional magnetic resonance imaging neurofeedback and sham biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Evaluating the Effectiveness of the General Practitioner Involvement in Cancer Screening Invitations
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Cervical Cancer
Interventions: OTHER: Normal invitation|OTHER: revised invitation signed by the coordinating doctor|OTHER: Revised invitation signed by the attending physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study in ALS With Abatacept & IL-2
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Abatacept Injection [Orencia] and Proleukin (aldesleukin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bethanechol on Glucose Homeostasis
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: Bethanechol (25 mg)|DRUG: Bethanechol (50 mg)|DRUG: Bethanechol (100 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Ascending-dose Study of the Efficacy, Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Participants
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: REGN1908-1909|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dry Cupping Therapy on Rotator Cuff Injuries
Status: COMPLETED
Conditions: Rotator Cuff Injuries|Shoulder Pain|Subacromial Impingement Syndrome
Interventions: OTHER: Dry Cupping Therapy|OTHER: Conservative Treatment (hotpack, transcutaneous electrical nerve stimulation(TENS), ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) B-cell Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Leukemia
Interventions: BIOLOGICAL: IM19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Study to Compare Results of Pelvic Organ Prolapse Repair With One Versus Two Vaginal Meshes
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: One mesh Endofast reliant system|DEVICE: two meshes Endofast reliant system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 24 Weeks of Oral Treatment With BIIL 284 BS in Adult and Pediatric Patients
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: BIIL 283 BS (Amelubent)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: LALAK for Opacities
Status: WITHDRAWN
Conditions: STROMAL OPACITIES
Interventions: PROCEDURE: LALAK|PROCEDURE: IEK|DRUG: Retrobulbar Block or General Anesthesia|DEVICE: optical coherence tomography (OCT)|DRUG: Topical Anesthesia|DEVICE: femtosecond laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 52 Week, International, Multi-center, Randomized, Double-blind, Double-dummy, Parallel-group Clinical Trial to Compare Retention on Treatment, Safety, Tolerability & Efficacy of Lumiracoxib 100 mg od, Lumiracoxib 100 mg Bid & Celecoxib 200 mg od in Pts With Primary OA of Hip, Knee, Hand or Spine
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Lumiracoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Non-interventional, Long-term Follow-up of Subjects Who Completed ApoGraft-01 Study
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Non Hodgkin Lymphoma (NHL)|Hodgkin Lymphoma, Adult
Interventions: OTHER: non intervational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing
Status: COMPLETED
Conditions: Surgical Site Infection|Complication,Postoperative|Surgical Wound Infection|Surgical Complication
Interventions: DEVICE: negative preassure wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Intramuscular A/H5N1 Inactivated, Split Virion Pandemic Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Influenza|Orthomyxoviridae Infections
Interventions: BIOLOGICAL: A/H5N1 inactivated, split-virion influenza virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes
Status: ACTIVE_NOT_RECRUITING
Conditions: Nicotine Vaping
Interventions: OTHER: Nicotine vaping visit 1 (free-base nicotine)|OTHER: Nicotine vaping visit 1 (protonated nicotine)|OTHER: Nicotine vaping visit 2 (free-base nicotine)|OTHER: Nicotine vaping visit 2 (protonated nicotine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Chronic Leg Ulcers With Autologous Stromal Vascular Fraction
Status: UNKNOWN
Conditions: Leg Ulcer
Interventions: PROCEDURE: Liposuction|OTHER: Standard wound care|DRUG: Adipose-Derived Regenerative Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Psychological Distress in Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Neoplasms|Psychological Distress|Prognosis Factors|Lifestyle, Healthy|IMMUNOTHERAPY|Targeted Molecular Therapy
Interventions: DRUG: immunotherapy|DRUG: Targeted Therapy Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis
Status: WITHDRAWN
Conditions: Anemia, Sickle Cell|Sickle Cell Anemia|Sickle Cell Disease|Sickle Cell Disorders|Hemoglobin SC Disease|Sickle Cell Hemoglobin C Disease
Interventions: DRUG: MP4CO|DRUG: Sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib + mFOLFOX for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Cancer
Interventions: DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Oxaliplatin|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Trial of OPC-61815 Injection in Patients With Congestive Heart Failure Who Have Difficulty With or Are Incapable of Oral Intake
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: OPC-61815 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: BI 10773|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PET With [18F]Flumazenil as an Index of Neurodegeneration in MS
Status: UNKNOWN
Conditions: Multiple Sclerosis|Relapsing-Remitting Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: PET with [11C]Flumazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Topical 5% Permethrin and Topical 10% Sulfur in the Treatment of Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Permethrin|DRUG: Sulphur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of AZARGA® as Replacement Therapy in Patients on COMBIGAN® Therapy in Canada
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Open-angle Glaucoma
Interventions: DRUG: Brinzolamide 1% / timolol 0.5% maleate fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: DRUG: PNB Bupivacaine|DRUG: PAI Ropivacaine|DRUG: PAI liposomal bupivacaine|DRUG: Epinephrine|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dairy Consumption During a High-intensity, High-volume Training Week in Young Athletes
Status: COMPLETED
Conditions: Inflammatory Response|Sports Performance
Interventions: OTHER: Greek Yogurt|OTHER: Isoenergetic carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Craniocervical Neural Mobilization on Quality of Life in Patients With Primary Tension Headache
Status: NOT_YET_RECRUITING
Conditions: Tension-Type Headache
Interventions: OTHER: craniocervical neural mobilization|OTHER: selected physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An International Multicenter, Randomized, Double-blind, Placebo-Controlled Clinical Study of Efficacy and Safety of Two Dosing Regimens of BCD-085 (JSC BIOCAD, Russia) in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: BCD-085 Q2W|DRUG: BCD-085 Q4W|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bivalent Norovirus Vaccine Study
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: BIOLOGICAL: NoV GI.1/GII.4 Bivalent VLP Vaccine|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects
Status: COMPLETED
Conditions: Acute Major Bleeding|Reversal of Coagulopathy
Interventions: BIOLOGICAL: BE1116 (Prothrombin Complex Concentrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Peripheral Magnetic Stimulation Compare to Dry Needling in Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: DEVICE: Repetitive Peripheral Magnetic Stimulation|PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Maple Trials Cat Allergen Natural Exposure Chamber Validation in Cat-allergic Subjects
Status: COMPLETED
Conditions: Allergic Rhinitis|Rhinoconjunctivitis|Exposure
Interventions: OTHER: Allergen Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomised Comparison of 2 Cold Snare Polypectomy Techniques
Status: COMPLETED
Conditions: Bowel Cancer
Interventions: PROCEDURE: conventional cold snare polypectomy|PROCEDURE: Cold snare polypectomy with suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence
Status: RECRUITING
Conditions: Adults Treated During Childhood or Adolescence for a Malignant Bone Tumor (Osteosarcoma and Ewing Sarcoma)
Interventions: PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Compare the PK , Safety, Tolerability, and Immunogenicity of HLX13 With YERVOY in Male Subjects
Status: RECRUITING
Conditions: Healthy Male Volunteers
Interventions: DRUG: HLX13|DRUG: CN-sourced ipilimumab|DRUG: EU-sourced ipilimumab group|DRUG: US-sourced ipilimumab group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant
Status: UNKNOWN
Conditions: Disorder Related to Renal Transplantation|Immunosuppression Related Infectious Disease|Virus Diseases
Interventions: DRUG: mTOR inhibitor (everolimus)|DRUG: cyclosporine or tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Doses of Grazoprevir (MK-5172) Given With Pegylated Interferon Alfa-2b and Ribavirin to Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-038)
Status: COMPLETED
Conditions: Chronic Hepatitis C (CHC)
Interventions: DRUG: Grazoprevir|BIOLOGICAL: pegylated interferon alfa-2b|DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routinely Deferred Versus Early Intervention in Elderly Patients With Non-ST-elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Non-ST Elevation Myocardial Infarction
Interventions: PROCEDURE: early coronary angiography|PROCEDURE: delayed coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New Drug
Status: COMPLETED
Conditions: Epilepsy, Tonic-Clonic
Interventions: DRUG: lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
Status: COMPLETED
Conditions: Wrinkles
Interventions: DRUG: onabotulinumtoxinA|DRUG: JUVÉDERM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholecystectomy vs EUS-guided GBD With Stone Removal
Status: RECRUITING
Conditions: Cholelithiasis
Interventions: PROCEDURE: LAMS placement for cholecystostomy|PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for Edema of the Macula in Diabetes: Protocol 3 With High Dose - the READ 3 Study
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Probiotics in Diabetic Cardiopathies With Excessive Weight
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2 in Obese|Anxiety|Cardiopathy
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Cleft Palate
Interventions: OTHER: back sleep positioning|OTHER: side sleep positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Split-Dose R-CHOP for Older Adults With DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|DLBCL|Cancer
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of CAOMECS Transplantation to Patients With Total Limbal Stem Cell Deficiency
Status: WITHDRAWN
Conditions: Limbal Stem Cell Deficiency
Interventions: PROCEDURE: Surgical transplantation of CAOMECS to the ocular surface
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of CM326 in Healthy Volunteers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CM326|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Cardiopulmonary Bypass Flow on Renal Oxygenation, Blood Flow and Tubular Injury
Status: COMPLETED
Conditions: Extracorporeal Circulation; Complications|Renal Failure|Circulation Disorder|Renal Plasma Flow, Effective|Cardiopulmonary Bypass|Hemolysis|Inflammatory Response
Interventions: PROCEDURE: High CPB flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Sertindole and Risperidone on Endophenotypic Markers of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: risperidone|DRUG: Sertindole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing the Safety and Efficacy of First-line Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Calcium folinate|DRUG: Fluorouracil|PROCEDURE: Diagnostic laparoscopy|COMBINATION_PRODUCT: dPIPAC ( The description of the standard diagnostic laparoscopy procedure and the session of PIPAC (dPIPAC)).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Time to Initiate Antiretroviral Therapy in HIV & TB Coinfected Adults Being Treated for Tuberculosis
Status: UNKNOWN
Conditions: Acquired Immunodeficiency Syndrome|Tuberculosis
Interventions: OTHER: Comparison of different treatment strategies|OTHER: Comparison of different treatment strategies|OTHER: Comparison of different treatment strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dragon III-Phase 3: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Neoadjuvant Chemotherapy
Interventions: DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cerebral Blood Flow in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain
Status: COMPLETED
Conditions: Pain|Low Back Pain|Leg Pain
Interventions: OTHER: Precision Spinal Cord Stimulation and PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle Arthropathy
Status: COMPLETED
Conditions: Haemophilia A|Haemophilia B
Interventions: DEVICE: custom-molded insoles and custom-molded shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
Status: RECRUITING
Conditions: Hematologic Malignancy|Leukemia|Lymphoma|Acute Lymphocytic Leukemia|ALL|Acute Myelogenous Leukemia|AML|Chronic Myelogenous Leukemia|CML|Myeloproliferative Neoplasm|Non Hodgkin Lymphoma|Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Burkitt Lymphoma|T-cell Lymphoma|B Cell Lymphoma|Peripheral T Cell Lymphoma|Cutaneous B-Cell Lymphoma
Interventions: OTHER: 1. Drug: The Venetoclax PK study is collecting bodily fluid samples (ie., whole blood and optional cerebrospinal fluid) of patients prescribed venetoclax as crushed tablets per standard of care.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does the Implementation of Nurse-driven HIV Screening for Key Populations in the Emergency Departments Limit Undiagnosed Infections in the Paris Metropolitan Area? DEPIST Trial (ANRS 14055)
Status: UNKNOWN
Conditions: Hiv|Nurse's Role
Interventions: PROCEDURE: Nurse-driven HIV screening for key populations combined with usual physician-directed diagnostic testing|OTHER: Physician-directed diagnostic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy of the PARI LC Sprint Sp Nebulizer for Acute Asthma Attack in Hospitalized Children Less Than 36 Months of Age
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Standard nebulizer|DEVICE: PARI LC Sprint Sp nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|DRUG: gemcitabine hydrochloride|DRUG: melphalan|DRUG: paclitaxel|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: toothpaste 1 with maximum fluoride concentration|OTHER: toothpaste 2 with 1000 ppm of fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of DHA/Oat on Metabolic Health in Gestational Diabetes Mellitus
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: oat grains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Patient Reporting of Side Effects to Chemotherapy: A Cluster Randomized Controlled Trial
Status: COMPLETED
Conditions: Adverse Event|Cancer, Breast|Chemotherapeutic Toxicity|Patient Outcomes Assessments
Interventions: OTHER: Completion of PRO-CTCAE items before consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aprepitant to Mitigate Opioids' Cognitive Side Effects
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of PD-1 Monoclonal Antibody in Combination With rhG-CSF, IL-2, and CapeOX in Initially Resectable Synchronous Colorectal Liver Metastases
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Tislelizumab|DRUG: Interleukin-2|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Neupogen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Efficacy of Rapid-acting Aspart and Faster Acting Aspart Within the Context of Single-hormone Closed-loop Strategy at Regulating Postprandial Glucose Levels
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Insulin pump|DEVICE: Continuous glucose monitoring system|OTHER: 11-hour intervention with the single-hormone artificial pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine
Status: COMPLETED
Conditions: Opioid Dependence|Opioid Related Disorders
Interventions: DRUG: SUBOXONE|DRUG: RBP-6000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
Status: RECRUITING
Conditions: Ewing Sarcoma|Rhabdomyosarcoma|Synovial Sarcoma
Interventions: BIOLOGICAL: Peptide vaccine IPX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol
Status: COMPLETED
Conditions: Severe Distal Tibia Injury|Severe Ankle Injury|Severe Foot Injury|Major Soft Tissue Loss|Major Bone Articular Surface Loss|Major Ankle Articular Surface Loss
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms?
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Depressive Symptoms|Derailment|Anxiety
Interventions: BEHAVIORAL: Derailment-Focused Reflective Journaling|OTHER: Everyday Tasks Reflective Journaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the SEM Scanner 200 for the Detection of Early Pressure Ulcers: A Multi-Site Longitudinal Study
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: DEVICE: Use of SEM200 Scanner daily|OTHER: Assessment and treatment of Pressure Ulcers using SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Premie DCD Imaging Intervention Study
Status: UNKNOWN
Conditions: Motor Skills Disorders|Premature Birth
Interventions: BEHAVIORAL: Cognitive Orientation to Occupational Performance (CO-OP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in South Korea Using Medical Records to Look at Different Treatments for Chronic Obstructive Airway Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Long-acting Muscarinic Antagonists (LAMA)|DRUG: Inhaled corticosteroid (ICS)/Long-acting Beta Agonists (LABA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thermogenic Properties of Zantrex-3
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Thermogenic properties of Zantrex-3®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome
Status: COMPLETED
Conditions: Marfan Syndrome
Interventions: DRUG: Atenolol|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Kenya
Status: WITHDRAWN
Conditions: Malaria
Interventions: DEVICE: Spatial Repellent product with active ingredient|DEVICE: Active ingredient|DEVICE: Spatial Repellent product without active ingredient (SHIELD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hepatitis C in Renal Transplant Recipients
Status: UNKNOWN
Conditions: Chronic Hepatitis C-virus Infection|Renal Transplantation
Interventions: DRUG: tacrolimus-cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine Plus (+) Trastuzumab vs Docetaxel Plus (+) Trastuzumab as 1 Line Treatment for HER2 Positive (+) Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: vinorelbine|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Novel Gaming System on Post-operative Rehabilitation Outcomes After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Arthroplasty, Replacement|Physical Therapy
Interventions: DEVICE: Game-based rehabilitation exercise|OTHER: Conventional brochures of rehabilitation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT