pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: RESTART the Prevention of Pressure Ulcers: Comparing the Effectiveness and Cost of a Reactive Static Air Mattress and Alternating Air Pressure Mattress
Status: RECRUITING
Conditions: Pressure Injury|Pressure Ulcer|Decubitus Ulcer
Interventions: DEVICE: Reactive static air support surfaces
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Life Beyond Trauma: 1-on-1 e-Health Program for Parents of Neurodiverse Children
Status: COMPLETED
Conditions: Post Traumatic Stress Injury|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: e-Net for Parents of Neurodiverse Children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recurrent Carotid Stenosis
Status: COMPLETED
Conditions: Cardiovascular Diseases|Carotid Stenosis|Cerebrovascular Disorders|Heart Diseases|Vascular Diseases
Interventions: DRUG: aspirin|DRUG: dipyridamole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The FAIS-Trial: Faecal Microbiota Transplantation (FMT) in Adolescents With Refractory Irritable Bowel Syndrome (IBS)
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Allogeneic faecal transplantation|OTHER: Autologous faecal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ICP-248 in Mature B-cell Malignancies
Status: NOT_YET_RECRUITING
Conditions: Mature B-cell Malignancies
Interventions: DRUG: ICP-248
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)|Deficient Emotional Self-Regulation (DESR)
Interventions: DRUG: ADHD Medication|DRUG: Omega-3 Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Effect of Protein Quality on Post-exercise Anabolism in Active Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Dietary Proteins
Interventions: DIETARY_SUPPLEMENT: Milk Protein Concentrate|DIETARY_SUPPLEMENT: Rice Protein Isolate|DIETARY_SUPPLEMENT: Soy Protein Isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Anti-adhesive Effect and Safety of MEDICURTAIN Applied to Undergoing Thyroid Surgery (Pivotal Study)
Status: COMPLETED
Conditions: Tissue Adhesion, Surgery-Induced
Interventions: DEVICE: GUARDIX-SG®|DEVICE: Medicurtain®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability and Short Term Efficacy of Extracorporeal Specific Immunoadsorption LupusorbTM Columns for the Treatment of Systemic Lupus Erythematosus (SLE) Patients
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DEVICE: LupusorbTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms
Status: COMPLETED
Conditions: Dry Eye
Interventions: DIETARY_SUPPLEMENT: Oral supplement containing omega-3 and omega-6|DIETARY_SUPPLEMENT: Oral supplement containing coconut and olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency
Status: COMPLETED
Conditions: Antibiotic Toxicity
Interventions: DRUG: Polymyxin B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Re-Evaluating the Inhibition of Stress Erosions: Gastrointestinal Bleeding Prophylaxis In ICU
Status: COMPLETED
Conditions: Stress Ulcer Prophylaxis
Interventions: DRUG: Pantoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of Rifampin on Single-Dose Pharmacokinetics of Canagliflozin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rifampin|DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Novel Lung Function Parameters in Patients With Bronchial Asthma
Status: COMPLETED
Conditions: Bronchial Asthma|Pulmonary Healthy Controls
Interventions: DIAGNOSTIC_TEST: impulse oscillometry|DIAGNOSTIC_TEST: multiple breath washout test|DIAGNOSTIC_TEST: body plethysmography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Packed Red Blood Cell Transfusion During Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: Packed Red Blood Cells (1 unit)|DRUG: Packed Red Blood Cells (2 units)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tertiary Prevention in Type II Diabetes Mellitus in Canary Islands Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Intervention to patients|BEHAVIORAL: Intervention to professionals|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host Disease
Status: TERMINATED
Conditions: Chronic Graft Versus Host Disease cGVHD
Interventions: DRUG: Efavaleukin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients
Status: RECRUITING
Conditions: Respiratory Failure
Interventions: DEVICE: Close-loop FiO2 controller|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Insole Types in Painful Flexible Flatfoot
Status: COMPLETED
Conditions: Flatfoot
Interventions: DEVICE: CAD/CAM Insole|DEVICE: Semi-custom Insole|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
Status: COMPLETED
Conditions: Statin Intolerance
Interventions: DIETARY_SUPPLEMENT: Pure epicatechin capsules (50mg)|DRUG: Simvastatin (40mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Famotidine on the Drug Levels of Afimetoran in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Famotidine|DRUG: Afimetoran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive Intervention for Older Adults With Memory Decline: A Pilot Study
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: MEMO programme (Inst Universitaire de Geriatrie, Montreal)|BEHAVIORAL: External memory aids training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The API-CALF Study: Apixaban to Treat Calf Vein Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Deep Vein Thrombosis
Interventions: DRUG: Apixaban 2.5 MG Oral Tablet [ELIQUIS]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Effect Of Two Steady State Doses of PF 06882961 On Rosuvastatin And Midazolam Pharmacokinetics In Otherwise Healthy Adult Participants With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: PF-06882961|DRUG: Rosuvastatin|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Study Of Cetuximab Plus Dasatinib (BMS-354825) in Treating Advanced Solid Malignancies
Status: COMPLETED
Conditions: Malignant Solid Tumour
Interventions: DRUG: Dasatinib (BMS-354825)|DRUG: Cetuximab (Erbitux, C225)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2/3 Heterologous Boosting Study With Different Dose Levels of Monovalent SARS-CoV-2 rS Vaccines
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: NVX-CoV2373 (5μg)|BIOLOGICAL: NVX-CoV2601 (5μg)|BIOLOGICAL: NVX-CoV2601(5μg)|BIOLOGICAL: NVX-CoV2601 (35μg)|BIOLOGICAL: NVX-CoV2601(35μg)|BIOLOGICAL: NVX-CoV2601(50μg)|BIOLOGICAL: Bivalent BA.4/5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of a Short Term Supplementation With Ubiquinol on Diverse Aspects Related to the Physical Activity
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Muscle Injury
Interventions: DIETARY_SUPPLEMENT: Ubiquinol|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Observation of Side Effects and Effectiveness of Desloratadine (Aerius) Syrup in Filipino Children (Study P05634)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Rhinitis, Allergic, Perennial|Urticaria
Interventions: DRUG: Desloratadine Syrup
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis
Status: RECRUITING
Conditions: NASH
Interventions: DRUG: K-877-ER|DRUG: CSG452|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Focused Ultrasound in Treating Participants With Intermediate and High-risk Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer Stage I AJCC V6|Prostate Cancer Stage II|Prostate Cancer Stage III
Interventions: PROCEDURE: Contrast-Enhanced Ultrasound|DEVICE: High-Intensity Focused Ultrasound|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Multiparametric Magnetic Resonance Imaging|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the In-Space Device for Treatment of Moderate Spinal Stenosis
Status: TERMINATED
Conditions: Spinal Stenosis
Interventions: DEVICE: Interspinous Spacer device|DEVICE: Interspinous Process Distraction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment With Green Tea Extract and Statins in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Green Tea Extract - Catechins|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Implementation Intentions to Self-incentivise Weight-loss
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: Single self-incentivising implementation intention|BEHAVIORAL: Multiple self-incentivising implementation intentions|BEHAVIORAL: Self-generated self-incentivising implementation intentions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Autism
Interventions: BEHAVIORAL: Intensive Center-Based Pivotal Response Treatment (PRT-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Intravaginal Electro-stimulation at Home by GYNEFFIK® Compared to Usual Care in Incontinent Patients With Prior Perineal Reeducation
Status: UNKNOWN
Conditions: Urinary Stress Incontinence|Urinary Mixed Incontinence
Interventions: DEVICE: GYNEFFIK(R)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced-dose Radiotherapy for Stage III Nasopharyngeal Carcinoma Based on the Treatment Response
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: PD-1 blocking antibody|DRUG: Gemcitabine|DRUG: Cisplatin (80 mg/m2)|RADIATION: Reduced-dose Intensity-modulated radiotherapy|RADIATION: Conventional-dose Intensity-modulated radiotherapy|DRUG: Cisplatin (100 mg/m2)|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 10% Salicylic Acid in Patients With Chronic Psoriasis Capitis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: Dimethicone|DRUG: Salicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Intravitreal AVD-104 in Diabetic Macular Edema
Status: TERMINATED
Conditions: Diabetic Macular Edema|Diabetic Retinopathy
Interventions: DRUG: AVD-104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Effects of Rotigotine Transdermal System in Subjects With Advanced-stage Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine|OTHER: Placebo|DRUG: Moxifloxacin infusion|OTHER: Placebo infusion|OTHER: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Current Cathode and Anode Effects and Changes in Handgrip Strength. Evaluation Through a Dynamometer Test
Status: COMPLETED
Conditions: Handgrip Strength
Interventions: DEVICE: Cathode stimulation|DEVICE: Anode stimulation|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Sun Protection Factor (SPF) of Sunscreen Products
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: DRUG: ChapStick Lip Moisturizer Original|DRUG: ChapStick Lip Moisturizer Mint|DRUG: ChapStick Lip Moisturizer Black Cherry|DRUG: SPF Standard Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Budesonide Combined With Formoterol and Tiotropium in the Treatment of Acute Exacerbation of ACO
Status: UNKNOWN
Conditions: Asthma-COPD Overlap
Interventions: DRUG: triple combinations|DRUG: double combinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Use of Radiographs Versus Patient Empowerment (CURVE)
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Patient-empowered follow up|OTHER: Standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Therapeutic Use of Intravenous Vitamin C in Allogeneic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Lymphoid Leukemia|Myeloid Leukemia|Monocytic Leukemia|Myelodysplasia
Interventions: DRUG: Intravenous (IV) and oral Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BAT8007 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AndraTec PMCF Study : Investigating the AndraTec Guidewires,PTA Balloons and Stents in Iliac Disease.
Status: WITHDRAWN
Conditions: Iliac Artery Disease|Peripheral Artery Disease
Interventions: DEVICE: 1 or more AndraTec devices (see description for list of devices)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Benefit of Adding Chemotherapy for Advance Nasopharyngeal Carcinoma (T1-4N2-3M0)
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms|Carcinoma, Squamous Cell
Interventions: PROCEDURE: Conventional RT|DRUG: Cisplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance and Safety of MEX-CD1 Low-volume Continuous Veno-venous Haemodialysis Medical Device for Copper-extraction in Patients With Wilson's Disease
Status: RECRUITING
Conditions: Hepatolenticular Degeneration; Wilson
Interventions: DEVICE: Low-volume continuous veno-venous haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX
Status: UNKNOWN
Conditions: Acute Coronary Syndromes|STEMI|NSTEMI
Interventions: OTHER: trans-radial and short-term bivalirudin|OTHER: trans-radial and long-term bivalirudin infusion|OTHER: trans-radial and standard of care pharmacology|OTHER: Trans-femoral and Short-term bivalirudin|OTHER: trans-femoral and long-term bivalirudin infusion|OTHER: trans-femoral and standard of care pharmacology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Pharmacokinetics of CY6463 in Participants With Stable Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: CY6463|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mini Thoracoscopy vs Semirigid Thoracoscopy in Exudative Pleural Effusions
Status: COMPLETED
Conditions: Pleural Effusion
Interventions: PROCEDURE: Mini Thoracoscopy|PROCEDURE: SemiRigid Thoracoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures
Status: RECRUITING
Conditions: Ankle Fractures
Interventions: OTHER: Postoperative protocol (Immediate weight bearing)|OTHER: Postoperative Protocol (Delayed Weight Bearing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of Combined Immunization of sIPV, DTaP and HepA
Status: UNKNOWN
Conditions: Vaccination
Interventions: BIOLOGICAL: sIPV+DTaP+HepA|BIOLOGICAL: sIPV|BIOLOGICAL: DTaP|BIOLOGICAL: HepA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thoracoscopic Ablation for Lone Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Heart Diseases
Interventions: PROCEDURE: Thoracoscopic surgical ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Recurrent/Metastatic Head and Neck Cancers
Status: COMPLETED
Conditions: Recurrent Head and Neck Cancer|Metastatic Head and Neck Cancer
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome, intravenous injection (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: orelabrutinib|DRUG: Sintilimab|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Limicol on LDL-cholesterol
Status: COMPLETED
Conditions: Hypercholesteremia
Interventions: DIETARY_SUPPLEMENT: Limicol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BCMA Targeted CAR T Cells With or Without Lenalidomide for the Treatment of Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: EGFRt/BCMA-41BBz CAR T cell|DRUG: Cyclophosphamide|DRUG: Lenalidomide.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-week Study Assessing the Onset of Effect Questionnaire (OEQ) Administered Daily Versus Weekly in Adult Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol pMDI|DRUG: Budesonide HFA pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exer Gaming on Balance and Gait in Parkinson's Patients
Status: COMPLETED
Conditions: Parkinson Disease|Balance
Interventions: COMBINATION_PRODUCT: Exer gaming|COMBINATION_PRODUCT: conventional treatment plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Six Months Versus 12 Months of Oral Itraconazole Therapy for Management of Treatment naïve Subjects With CPA
Status: COMPLETED
Conditions: Chronic Pulmonary Aspergillosis
Interventions: DRUG: Itraconazole 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine for the Prevention of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea
Interventions: DRUG: Placebo|DRUG: 5 mg Olanzapine Tablets|DRUG: 10 mg Olanzapine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Intervention Versus Surgery in the Treatment of Common Femoral Artery Lesions
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Artery Stenosis
Interventions: DEVICE: Atherectomy and paclitaxel-coated balloon angioplasty|PROCEDURE: Open, surgical endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Intravenous Talineuren (TLN) in Parkinson's Disease-affected Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Talineuren
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cladribine Plus Low Dose Cytarabine (LDAC) Alternating With Decitabine in Patients With Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)
Status: RECRUITING
Conditions: Leukemia
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Exercise Program for Patients With Femoro-acetabular Impingement
Status: ACTIVE_NOT_RECRUITING
Conditions: Femoracetabular Impingement
Interventions: OTHER: Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Non-cultured Epidermal Cellular Grafting vs Hyaluronic Acid for Repigmenting Vitiligo and Piebaldism
Status: COMPLETED
Conditions: Vitiligo|Piebaldism
Interventions: DEVICE: VITICELL|DEVICE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the 24-Hour Pulmonary Function Profile of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25mcg Once Daily Compared With Tiotropium Bromide Inhalation Powder 18mcg Once Daily in Subjects With COPD Who Have or Are At Risk for Co-morbid Cardiovascular Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone furoate/vilanterol 100/25mcg|DRUG: tiotropium bromide 18mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Ban on Smoking in Pubs, Restaurants and Nightclubs on Endothelial Function in Workers
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Medical interrogatory|OTHER: Medical examination|OTHER: Specific bioassay|OTHER: Endothelial function evaluation|OTHER: General bioassay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility of Telehealth Palliative Care and Digital Symptom Monitoring for Patients With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: OTHER: Palliative Care + Digital Symptom Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Depression and Anxiety: A Cystic Fibrosis-Specific Cognitive Behavioral Therapy Intervention
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: CF-CBT: A Cognitive-Behavioral Skills-Based Program to Promote Emotional Well-Being for Adults wtih Cystic Fibrosis|BEHAVIORAL: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intensified, Inpatient Adaptation of Dialectical Behavior Therapy (DBT)
Status: UNKNOWN
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: standard outpatient DBT|BEHAVIORAL: Inpatient Adaptation of DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely
Status: TERMINATED
Conditions: Preterm Delivery|Inadequate Milk Production
Interventions: DRUG: Merotocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atrophic Gastritis Predicts the Risk of Gastric Cancer
Status: RECRUITING
Conditions: Atrophic Gastritis
Interventions: OTHER: Esophagogastroscopy (OLGA 0-Ⅰ)|OTHER: Esophagogastroscopy (OLGA II)|OTHER: Esophagogastroscopy (OLGA III-IV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of OMS302 in Subjects Undergoing Unilateral Cataract Extraction With Lens Replacement (CELR)
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: OMS302 Solution|DRUG: OMS302 Mydriatic Solution|DRUG: OMS302 Anti-inflammatory Solution|DRUG: Balanced Salt Solution (BSS) Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ceramic Versus Composite in the Treatment of Posterior Teeth by Inlays or Onlays
Status: COMPLETED
Conditions: Dental Caries|Inlays
Interventions: DEVICE: ceramic (Empress CAD, Ivoclar Vivadent)|DEVICE: composite (Lava Ultimate, 3M Espe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis (IVSR-UC)
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: Visilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Dexmedetomidine Hydrochloride Injection in Anesthesia for Patients Without Tracheal Intubation
Status: UNKNOWN
Conditions: Sedation Complication
Interventions: DRUG: Dexmedetomidine Hydrochloride 0.1 MG/ML|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Self-Compassion and Vagal Nerve Stimulation on Heart Rate Variability, Psychological Resilience, and Sleep Quality
Status: NOT_YET_RECRUITING
Conditions: Heart Rate Variability|Psychological Resilience|Sleep Quality
Interventions: BEHAVIORAL: Mindfulness Based Self Compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, and Tolerability of an Intramuscular Formulation of Aripiprazole (OPC-14597) as Maintenance Treatment in Bipolar I Patients
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Intramuscular (IM) Depot Aripiprazole|DRUG: Intramuscular (IM) Depot Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma|Recurrent Brain Neoplasm
Interventions: RADIATION: Palliative Radiation Therapy|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy Treatment Planning and Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histamine as a Molecular Transducer of Adaptation to Exercise
Status: RECRUITING
Conditions: Postexercise Hypotension
Interventions: BEHAVIORAL: Aerobic Exercise|DRUG: alpha-FMH|BEHAVIORAL: Resistance and Aerobic Exercise|DRUG: Antihistamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open Label, Single Arm, Phase II Study Using R-COMP in Elderly Patients With Aggressive NHL.
Status: UNKNOWN
Conditions: Aggressive Non-Hodgkin's Lymphoma in the Elderly.
Interventions: DRUG: Cyclophosphamide, oncovin, myocet, prednisone & rituximab (R-COMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Mental Health Diagnoses and Treatment Plans: A Protocol for Actors and Patients
Status: RECRUITING
Conditions: Mental Health Diagnosis
Interventions: DIAGNOSTIC_TEST: SP patients-actors|DIAGNOSTIC_TEST: Patients|DIAGNOSTIC_TEST: Control group- patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: L-C Ligament Versus Hamstring Autograft for Primary ACL Reconstruction
Status: TERMINATED
Conditions: Acute Ruptures of the Anterior Cruciate Ligament
Interventions: DEVICE: L-C Ligament|PROCEDURE: Hamstring Autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study
Status: RECRUITING
Conditions: Prolonged Anticoagulation|Venous Thromboembolic Disease|Autoimmune Hemolytic Anemia
Interventions: DRUG: treatment "intervention"|DRUG: treatment "standard"|BIOLOGICAL: biological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical Airway Block on Hemodynamic Stability Post Induction of Anaesthesia in Cardiac Surgeries
Status: RECRUITING
Conditions: Cardiac Surgery
Interventions: DRUG: Fentanyl|DRUG: Lidocain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Oral Panobinostat in Adult Participants With Relapsed/Refractory Classical Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Classical Hodgkin's Lymphoma
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Carboplatin for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: RECRUITING
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Carboplatin|BIOLOGICAL: Pembrolizumab|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Hypoallergenicity Study on a New Rice-Based Hydrolysate Formula
Status: COMPLETED
Conditions: Allergy;Food
Interventions: OTHER: New Rice-based hydrolysate|OTHER: Amino Acid-based infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Targeting CD19 and BCMA CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: KQ-2003 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Response of Cannabidiol in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Cannabis
Interventions: DRUG: 200mg Cannabidiol by capsules twice daily|DRUG: 400mg Cannabidiol by capsules twice daily|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding MgSO4 to Epidural Levobupivacaine in CS for Patients With Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Levobupivacaine hydrochloride|DRUG: Magnesium sulphate|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Rucaparib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sintilimab With P-GemOx Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-cell Lymphoma, Nasal Type
Status: RECRUITING
Conditions: NK/T Cell Lymphoma Nos
Interventions: DRUG: sintilimab,pegaspargase,gemcitabine,oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Versus Proximal Protection on Cerebral Microembolization During High-risk Carotid Artery Stenting
Status: WITHDRAWN
Conditions: Stroke|Carotid Stenosis
Interventions: DEVICE: proximal embolism protection device|DEVICE: distal embolism protection device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Individualized and Standardized Acupuncture Treatment for Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Individualized Acupuncture|PROCEDURE: Standardized Acupuncture|PROCEDURE: Sham Acupuncture|OTHER: Waiting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer
Status: RECRUITING
Conditions: Stage III Thymoma AJCC v8|Stage IIIA Thymoma AJCC v8|Stage IIIB Thymoma AJCC v8|Stage IV Thymoma AJCC v8|Stage IVA Thymoma AJCC v8|Stage IVB Thymoma AJCC v8|Unresectable Thymic Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Coronary Artery Lesions Using the PRO-Kinetic Energy Cobalt-Chromium, Bare-Metal Stent
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PRO-Kinetic Energy Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Micro-energy Ultrasound in the Treatment of Renal Insufficiency After Renal Transplantation
Status: UNKNOWN
Conditions: Renal Insufficiency|Renal Transplantation
Interventions: DEVICE: ultrasonic therapeutic apparatus 1|DEVICE: ultrasonic therapeutic apparatus 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Functional Connectivity Targeting in aiTBS for Depression
Status: RECRUITING
Conditions: Depressive Disorder, Major|Depression|Mood Disorders|Mental Disorder|Psychiatric Disorder
Interventions: PROCEDURE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incentives & Motivation for Behavior Change:
Status: COMPLETED
Conditions: Behavior|Intention
Interventions: BEHAVIORAL: mandate public|BEHAVIORAL: employer mandate|BEHAVIORAL: incentive reward|BEHAVIORAL: penalty|BEHAVIORAL: incentive lottery small|BEHAVIORAL: incentive lottery medium|BEHAVIORAL: incentive lottery large|BEHAVIORAL: cash small|BEHAVIORAL: cash medium|BEHAVIORAL: cash large|BEHAVIORAL: invitation for exercise financial incentive study|BEHAVIORAL: invitation for exercise social incentive study|BEHAVIORAL: invitation for sleep social incentive study|BEHAVIORAL: invitation for sleep financial incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A 12-Day Randomized, Blinded, Vehicle and Active Comparator-Controlled Study to Determine the Efficacy and Safety of Six Concentrations of Topical E6201 Gel in Subjects With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: 0.03% E6201|DRUG: 0.1% E6201|DRUG: 0.2% E6201|DRUG: 0.005% E6201|DRUG: 0.01% E6201|DRUG: 0.05% E6201|OTHER: Placebo - 0.03% gel vehicle|OTHER: Placebo - 0.1% gel vehicle|OTHER: Placebo - 0.2% gel vehicle|OTHER: Placebo - 0.05% gel vehicle|OTHER: Placebo - 0.01% gel vehicle|OTHER: Placebo - 0.05% gel vehicle|DRUG: Calcipotriene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Inpatient Penicillin Allergy Delabeling Study
Status: COMPLETED
Conditions: Penicillin Allergy|Penicillin Sensitivity|Penicillin Reaction|Penicillin Intolerance
Interventions: DRUG: Graded Oral Amoxicillin Challenge|OTHER: De-labelling in electronic medical record|OTHER: Referral to Allergy Immunology/Retention of Allergy Label
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Memantine for Spasticity in MS Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: placebo|DRUG: memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety and Tolerability of Deferiprone in Patients With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: placebo|DRUG: deferiprone|DRUG: deferiprone|DRUG: placebo|DRUG: deferiprone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Humoral and Cellular Immunity Against SARS-COV-2 Vaccine in HIV-infected Patients Immunosuppressed
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 RNA Vaccines|HIV Infection
Interventions: BIOLOGICAL: SARS-CoV-2 Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Lyophilized Growth Factors for Subacromial Impingement
Status: UNKNOWN
Conditions: Shoulder Impingement Syndrome
Interventions: BIOLOGICAL: Growth factors|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Docosahexaenoic acid (DHA)|DRUG: Eicosapentaenoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: CRISPR/cas13-medIated RNA tarGeting tHerapy for the Treatment of Neovascular Age-related Macular Degeneration Investigator-initiated Trial (SIGHT-I)
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration(nAMD)
Interventions: GENETIC: HG202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
Status: RECRUITING
Conditions: Small-Cell Lung Cancer|Neuroendocrine Carcinoma
Interventions: BIOLOGICAL: MK-6070|BIOLOGICAL: Atezolizumab|BIOLOGICAL: Ifinatamab Deruxtecan (I-DXd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers
Status: COMPLETED
Conditions: Marfan Syndrome
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Risk-Adapted Therapy in Young Adult Acute Lymphoblastic Leukemia: a Multicenter Trial
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Collection of treatment-stratefying prognostic factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT