pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cabazitaxel With or Without Carboplatin in Treating Patients With Previously Treated Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration Levels of Testosterone|Castration-Resistant Prostate Carcinoma|Lymphadenopathy|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Prostate Carcinoma Metastatic in the Bone|Prostate Small Cell Carcinoma
Interventions: DRUG: Cabazitaxel|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Doses of BAY1902607 in Healthy Males and Proof of Concept in Chronic Cough Patients
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: BAY1902607|DRUG: Matching placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant
Status: RECRUITING
Conditions: Liver Transplant; Complications|Cirrhosis|End Stage Liver DIsease|Medication Adherence
Interventions: BEHAVIORAL: TEST Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevascar in African Continental Group Scarring
Status: UNKNOWN
Conditions: Scarring
Interventions: DRUG: Prevascar 5ng|DRUG: Prevascar 25ng|DRUG: Prevascar 100ng|DRUG: Prevascar 250ng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of OPN-375 Adults With Bilateral Nasal Polyps Using Nasoendoscopic Video
Status: COMPLETED
Conditions: Nasal Polyposis
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy
Status: COMPLETED
Conditions: Biliary Atresia
Interventions: DRUG: Lactobacillus casei rhamnosus (Lcr35)|DRUG: Neomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Compare the Success Rate of T3 Dental Implant (Biomet 3I) With or Without Platform-switch Concept
Status: UNKNOWN
Conditions: Implants|Bone Loss
Interventions: DEVICE: Dental Implant|DEVICE: Platform-Switch Dental Implant|DEVICE: Platform-Matched dental implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin (AAT) Deficiency
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: rAAV1-CB-hAAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Ketogenic Diet in Amnestic Mild Cognitive Impairments
Status: RECRUITING
Conditions: Amnestic Mild Cognitive Disorder|Amnestic Mild Cognitive Impairment
Interventions: OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEEP Follow Up: Evaluation of Repeatability of Lamotrigine Pharmacokinetics in Epileptic Patients
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: lamotrigine (brand Lamictal)|DRUG: lamotrigine (generic Teva)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Adding Sufentanyl to Bupivacaine in Transversus Abdominis Plane Block to Reduce the Narcotic Dosage and Pain After Cesarean Delivery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Sufentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lovastatin in Reducing Side Effects After Radiation Therapy in Women With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Radiation Toxicity
Interventions: DRUG: lovastatin|OTHER: questionnaire administration|PROCEDURE: adjuvant therapy|RADIATION: accelerated partial breast irradiation|RADIATION: external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of 3,4-DAP in Fatigue Associated With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: 3,4-diaminopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Fmri Study on the Effects of a Conjugate Vaccine and Placebo on CNS Activation and Behavior Following a Nicotine Challenge
Status: COMPLETED
Conditions: Nicotine Dependency|Smoking
Interventions: BIOLOGICAL: vaccination with Nicvax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Preoperative Herceptin/Navelbine Versus Taxotere/Carboplatin/Herceptin in HER-2 Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Herceptin|DRUG: Navelbine|DRUG: Taxotere|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RO4929097 in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Recently Completed Treatment With Front-Line Chemotherapy
Status: TERMINATED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIStreatment Screening in Elders Before Discharge
Status: RECRUITING
Conditions: Elder Abuse|Surveys and Questionnaires|Self Neglect|Geriatrics|Geriatric Assessment|Health Services for the Aged|Aged
Interventions: OTHER: NCAEM EM-SART Pre-Screen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess Safety & Tolerability of AZD2281 in Combination With Bevacizumab in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Neoplasm Metastasis
Interventions: DRUG: AZD2281|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pitolisant (BF2.649) in the Treatment of EDS in Patients With OSA
Status: COMPLETED
Conditions: Excessive Daytime Sleepiness|Obstructive Sleep Apnea
Interventions: DRUG: Pitolisant (BF2.649)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pressure-Controlled vs Volume-Controlled Ventilation During One Lung Ventilation
Status: SUSPENDED
Conditions: Thoracic Surgery
Interventions: OTHER: Pressure Controlled vs. Volume Controlled Ventilation during OLV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Reduction in Antihypertensive Treatment on Total Mortality in Frail Subjects With Low Systolic Blood Pressure: Study in Subjects Over 80 Years Living in Nursing Homes
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: OTHER: STEP DOWN strategy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Tofacitinib 2 mg|DRUG: Tofacitinib 5 mg|DRUG: Tofacitinib 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Inpatient Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease (COPD) III/IV
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: inpatient rehabiliation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CINCH-FMR Post-Market Registry: Percutaneous Repair in Functional Mitral Regurgitation
Status: ENROLLING_BY_INVITATION
Conditions: Functional Mitral Regurgitation|Mitral Regurgitation
Interventions: DEVICE: Carillon Mitral Contour System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-term Study of Mometasone Furoate in Patients With Perennial Allergic Rhinitis (Study P04459)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bed Mattress Sensor for Detecting Pre-fall Activities and Preventing Bedside Falls in Elderly in Residential Setting
Status: COMPLETED
Conditions: Technology
Interventions: DEVICE: Bed mattress sensor system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventing Falls and Participation Restrictions in Neurological Diseases
Status: COMPLETED
Conditions: Multiple Sclerosis|Parkinson Disease|Stroke
Interventions: OTHER: Experimental Group: Education|OTHER: Control Group: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Confirmatory Olmesartan Plaque Regression Study
Status: TERMINATED
Conditions: Essential Hypertension|Carotid Plaque
Interventions: DRUG: Atenolol|DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vivitrol Treatment for Cannabis Use Disorder
Status: UNKNOWN
Conditions: Cannabis Use Disorder
Interventions: DRUG: Naltrexone 380 MG [Vivitrol]|BEHAVIORAL: Motivational Enhancement Therapy and Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BGB-A425 and LBL-007 in Combination With Tislelizumab in Advanced Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2
Interventions: DRUG: BGB-A425|DRUG: Tislelizumab|DRUG: LBL-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Preterm Birth on Symptoms of Anxiety and Depression in Parents, and on the Precursors of Cognition, Including Social Cognition in Their Child
Status: RECRUITING
Conditions: Parental Anxiety Following Premature Birth
Interventions: BEHAVIORAL: State-Trait Anxiety Inventory - Y ou STAI-Y
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Pharmacokinetics of Infacort® Versus Immediate-release Hydrocortisone
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Infacort|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Triheptanoin Treatment Trial for Patients With Long-chain Fatty Acid Beta-oxidation Defects
Status: WITHDRAWN
Conditions: Long-chain Fatty Acid Transport Deficiency
Interventions: DRUG: Triheptanoin (SpezialölÒ 107®)|DIETARY_SUPPLEMENT: MCT (Medium-Chain Triglycerides)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Evaluation Exploring New Adhesive Materials and Their Ability to Adhere to Abdominal and Peristomal Skin
Status: RECRUITING
Conditions: Skin Abnormalities
Interventions: OTHER: Adhesive material|OTHER: Standard adhesive material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Impact of Dietary Treatment in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: FODMAP diet|OTHER: Elimination-rotational diet|OTHER: Classic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fecal Microbial Transplantation Treatment in Adults With Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Fecal Microbial Transplantation|BIOLOGICAL: placebo fecal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suramin and Either Docetaxel or Gemcitabine in Treating Patients With Stage IIIB or Stage IV Platinum-Refractory Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: suramin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Saccharomyces boulardii|DRUG: Amoxicillin Clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy and Safety of AVANZ® Phleum Pratense in Grass Pollen-induced Allergic Rhinitis During Controlled Exposure in an Environmental Challenge Chamber
Status: COMPLETED
Conditions: Grass Pollen Induced Allergic Rhinoconjunctivitis
Interventions: DRUG: AVANZ Phleum pratense 15,000 SQ+|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yôga and Breathing Techniques Training in Patients With Heart Failure and Preserved Ejection Fraction
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Failure|Heart Failure, Diastolic
Interventions: OTHER: Yôga|OTHER: Breathing technique|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Microfracture Combined With Suture Bridge Technique Versus Greenhouse Technique in Treating of Rotator Cuff Injuries
Status: UNKNOWN
Conditions: Rotator Cuff Tears|Microfractures
Interventions: PROCEDURE: Greenhouse Technique|PROCEDURE: Microfracture Combined With Suture Bridge Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Cancer|Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: ART0380|DRUG: Gemcitabine|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy
Status: COMPLETED
Conditions: Esophageal and Gastric Varices
Interventions: COMBINATION_PRODUCT: banding ligation plus terlipressin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Everolimus Trial in Laryngotracheal Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Subglottic Tracheal Stenosis
Interventions: DRUG: Everolimus Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-tumor Necrosis Factor in Patients With Ulcerative Colitis in Clinical Remission: to Continue or Not?
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis,Ulcerative
Interventions: OTHER: Discontinuation of anti-TNF treatment|OTHER: Continuation of anti-TNF treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Activity Adequacy Mindsets on Health and Wellbeing
Status: COMPLETED
Conditions: Activity Adequacy Mindsets
Interventions: BEHAVIORAL: Accurate step count feedback|BEHAVIORAL: Deflated step count feedback|BEHAVIORAL: Inflated step count feedback|BEHAVIORAL: Accurate feedback + mindset intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Exenatide on Postprandial Hyperlipidemia and Inflammation
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Impaired Glucose Tolerance
Interventions: DRUG: Exenatide|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphodepleting Chemotherapy|Myeloid Malignancies
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine phosphate|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin, 500 mg extended release tablet|DRUG: Metformin, 1000 mg extended release tablet|DRUG: Glimepiride, 1 mg immediate release tablet|DRUG: Glimepiride, 2 mg immediate release tablet|DRUG: Metformin, 500 mg and Glimepiride, 1 mg extended release film coated tablet containing release controlling polymers|DRUG: Metformin, 1000 mg and Glimepiride, 2 mg extended release film coated tablet containing release controlling polymers|DRUG: Metformin, 500 mg and Glimepiride, 1 mg extended release tablet coated with release controlling polymers|DRUG: Metformin, 1000 mg and Glimepiride, 2 mg extended release tablet coated with release controlling polymers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS for the Treatment of Neuropathic Pain in Diabetic Patients
Status: ENROLLING_BY_INVITATION
Conditions: Neuropathic Pain|Diabetic Neuropathies
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JointADventure: A Worksite Activity-Diet Intervention for Chronic Knee Pain
Status: COMPLETED
Conditions: Chronic Knee Pain|Osteoarthritis, Knee
Interventions: BEHAVIORAL: A worksite activity-diet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repeatability and Reproducibility of Multiparametric MRI
Status: UNKNOWN
Conditions: Liver Diseases|Primary Biliary Cirrhosis|Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis|Cirrhosis|Hemochromatosis|Viral Hepatitis|Autoimmune Hepatitis|Primary Sclerosing Cholangitis
Interventions: DEVICE: LiverMultiScan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Idebenone for the Preventive Treatment of Migraine
Status: RECRUITING
Conditions: Migraine Disorders|Headache Disorders
Interventions: DRUG: Placebo|DRUG: 90mg Idebenone|DRUG: 270mg Idebenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Injection for Common Upper Extremity Problems
Status: COMPLETED
Conditions: Lateral Elbow Pain
Interventions: DRUG: Placebo Injection|DRUG: Steroid (dexamethasone) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of Protein-Enriched Lacto-Vegetarian Soup on Muscle Mass and Muscle Strength Among Older Adults
Status: COMPLETED
Conditions: Sarcopenia|Muscle Loss|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Protein nutritional supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab pegol|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Dementia Caregiver Sleep & the Effect on Heart Disease Biomarkers
Status: COMPLETED
Conditions: Caregivers of Persons With Dementia
Interventions: BEHAVIORAL: Sleep Behavioral Therapy A and NHMS|BEHAVIORAL: Sleep Behavioral Therapy B and NHMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Piclidenoson for Treatment of COVID-19
Status: COMPLETED
Conditions: COVID-19|Coronavirus Infection
Interventions: DRUG: Piclidenoson|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Chemotherapy-Induced Peripheral Neuropathy (CIPN) Onset-Suppressing Effect and Safety of ONO-2910 in Patients With Breast Cancer Receiving Weekly Paclitaxel
Status: ACTIVE_NOT_RECRUITING
Conditions: CIPN - Chemotherapy-Induced Peripheral Neuropathy
Interventions: DRUG: ONO-2910|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TP0501 - Pharmaco-Scintigraphic-Study
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: TP05 Coating A|DRUG: TP05 Coating B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Ranolazine on Myocardial Perfusion Assessed by Serial Quantitative Exercise SPECT Imaging
Status: COMPLETED
Conditions: Myocardial Perfusion Imaging|Myocardial Ischemia
Interventions: DRUG: Ranolazine|DRUG: Placebo to match ranolazine|PROCEDURE: SPECT MPI|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of VIS410 to Assess Safety and Pharmacokinetics
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: VIS410|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat (MK-0683) Phase I Study in Cutaneous T-Cell Lymphoma (CTCL) Patients (MK-0683-089 EXT1)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy
Status: COMPLETED
Conditions: Kidney Failure
Interventions: DRUG: DDAVP|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psoriatic Oligoarthritis Intervention With Symptomatic thErapy
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Leflunomide|DRUG: Methylprednisolone|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Repair Versus High Tibial Osteotomy for Medial Meniscus Posterior Root Tears
Status: RECRUITING
Conditions: Medial Mensical Tear
Interventions: PROCEDURE: Arthroscopic Repair|PROCEDURE: High tibial osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) for Nicotine Addiction
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Simvastatin 20 mg daily|DIETARY_SUPPLEMENT: Folic acid 2 mg + vitamin B12 1 mg daily|DRUG: Simvastatin 80 mg daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-PD-1 Antibody Therapies of Camrelizumab in Combination With Pemetrexed and Carboplatin as First-line Treatment in Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Camrelizumab (SHR-1210), Pemetrexed, and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Prism Adaptation Therapy on Hemispatial Neglect
Status: TERMINATED
Conditions: Stroke|Recovery of Function|Rehabilitation|Perceptual Disorders|Virtual Reality Exposure Therapy
Interventions: DEVICE: Virtual Prism Adaptation Therapy|DEVICE: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) vs Placebo for Participants With Non-small Cell Lung Cancer After Resection With or Without Standard Adjuvant Therapy (MK-3475-091/KEYNOTE-091)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium and Riboflavin Treatment for Post-Concussion Headache
Status: RECRUITING
Conditions: Concussion, Intermediate
Interventions: DRUG: magnesium and riboflavin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Learning Impairments Among Survivors of Childhood Cancer
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Brain Tumors
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Dihydroartemisinin-piperaquine (DP)|OTHER: DP Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany
Status: RECRUITING
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Mentalization-Based Treatment (MBT)|BEHAVIORAL: Bona-Fide Treatment in Germany (BFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty Compared to Internal Fixation for Displaced Intracapsular Fractures of the Femoral Neck
Status: COMPLETED
Conditions: Femoral Neck Fracture
Interventions: PROCEDURE: Internal fixation|PROCEDURE: Total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of OMS103HP in Patients Undergoing Autograft Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Knee Injuries
Interventions: DRUG: OMS103HP|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESTORE Trial: A Pilot RCT of Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR) for Veterans With CPTSD
Status: UNKNOWN
Conditions: Complex Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Enhanced Skills Training in Affective and Interpersonal Regulation|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Ibrutinib in Pediatric and Young Adult Participants With Relapsed or Refractory Mature B-cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Ibrutinib|DRUG: Rituximab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Vincristine|DRUG: Idarubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise and Alagebrium on the Diastolic Function of the Heart
Status: COMPLETED
Conditions: Ventricular Function
Interventions: BEHAVIORAL: Aerobic Exercise Training|DRUG: Alagebrium (generic: ALT-711)|BEHAVIORAL: Tai Chi and/or Yoga Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lanthanum Carbonate on Fibroblast Growth Factor 23 ( FGF23) in Chronic Kidney Disease
Status: COMPLETED
Conditions: Metabolic Bone Disease
Interventions: DRUG: Lanthanum Carbonate (Fosrenol)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Left Ventricular Function Assessment After Acute Myocardial Infarction: Comparison Between Bi-, Three-dimensional and Cardiac Magnetic Resonance
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: OTHER: compare measurements of left ventricular volumes and LVEF (by Cardiac Magnetic Resonance and Echocardiography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Mesenchymal Stem Cells Transplantation in Cervical Chronic and Complete Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Autologous mesenchymal cells transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of EpCAM Receptors Using [99mTc]Tc(CO)3-(HE)3-Ec1
Status: ENROLLING_BY_INVITATION
Conditions: Solid Tumor, Adult
Interventions: DRUG: Diagnostic Test: whole body study and SPECT with [99mTc]Tc(CO)3-(HE)3-Ec1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cholinergic Mechanisms of Gait Dysfunction in Parkinson's Disease Experiments 1 & 2 - Proj #3
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cataract Surgery Combined With Endoscopic Goniosynechialysis for Advanced Primary Angle Closure Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Closed-Angle
Interventions: PROCEDURE: Cataract surgery with endoscopic goniosynechialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Clindamycin on Postoperative Endodontic Pain
Status: UNKNOWN
Conditions: Symptomatic Periapical Periodontitis
Interventions: DRUG: 600 mg Clindamycin orally|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine in Combination With Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: Decitabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers
Status: WITHDRAWN
Conditions: Contact Lens Dry Eye
Interventions: DRUG: Lifitegrast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Drug Eluting Sirolimus Stent Experience in Restenosis Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: CYPHER Sirolimus-eluting stent|DEVICE: Bx SONIC bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Subcutaneously Administered REGN475(SAR164877) in Patients With Sciatic Pain
Status: COMPLETED
Conditions: Sciatica
Interventions: DRUG: REGN475|DRUG: REGN475|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of HCP1105 in Combined Hyperlipidemic Patients With High Risk for CHD
Status: UNKNOWN
Conditions: Hyperlipidemias
Interventions: DRUG: HCP1105|DRUG: HGP0816|DRUG: Placebo of HCP1105|DRUG: Placebo of HGP0816
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery
Status: COMPLETED
Conditions: Corneal Edema After Cataract Surgery
Interventions: DRUG: Ripasudil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor
Status: UNKNOWN
Conditions: Labor Long|Labor Pain|Labor Fetal Anoxia
Interventions: PROCEDURE: Combined spinal-epidural analgesia|PROCEDURE: Epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Expanded Access Open-Label, Compassionate Use Protocol of Remune in HIV-1-Infected Adults With CD4 Count Less Than 300 Cells/Ml
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 Immunogen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0427, Combination Chemotherapy & RT in Treating Patients With Stage III or Stage IV Cancer of the Oropharynx
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: 5-fluorouracil|PROCEDURE: surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: Octanoic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Bolus Doses of Remifentanil on the Incidence of Coughing During Emergence of Anesthesia
Status: COMPLETED
Conditions: Cough|Anesthesia
Interventions: DRUG: Remifentanil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Augmented Reality to Promote Physical Activity in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Mobile Phone Use|Pediatric ALL|Physical Disability|Physical Inactivity
Interventions: DEVICE: Augment Reality Exergames
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Melanoma Treatment With White Blood Cells That Destroy MART Expressing Tumor Cells
Status: TERMINATED
Conditions: Metastatic Melanoma|Skin Cancer
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Aldesleukin|DRUG: MART-1 Reactive CD8+ PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Retention After Total Laparoscopic Hysterectomy With Immediate Foley Catheter Removal Versus Backfill Void Trial
Status: COMPLETED
Conditions: Urinary Retention|Voiding Disorders
Interventions: DEVICE: Void Trial using Foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Medytoxin® Treatment in Patients With Benign Masseteric Hypertrophy
Status: COMPLETED
Conditions: Hypertrophy of Masseter Muscle
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ultrasonographic Assessment of Efficacy of Injectable Hyaluronic Acid for Genitourinary Syndrome of Menopause
Status: COMPLETED
Conditions: Genitourinary Syndrome of Menopause|Sexual Function Disturbances
Interventions: DEVICE: injectable multifractional intercalated hyaluronic acid [Armonia®, Regenyal, Italy]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hematoma
Status: RECRUITING
Conditions: Chronic Subdural Hematoma|Recurrence
Interventions: BEHAVIORAL: Intracranial Hypotension Targeted(IHT) Body Posture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pasireotide LAR and Pegvisomant Study in Acromegaly
Status: UNKNOWN
Conditions: Acromegaly
Interventions: DRUG: Pasireotide LAR 60 mg|DRUG: Pegvisomant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Mirtazapine for Depression in IBD
Status: RECRUITING
Conditions: Major Depressive Disorder|Inflammatory Bowel Diseases
Interventions: DRUG: Mirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study
Status: COMPLETED
Conditions: Schistosomiasis
Interventions: DRUG: Praziquantel 600Mg Oral Tablet x 5|DRUG: Praziquantel 600Mg Oral Tablet x 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Intervention on Motivational Anhedonia of Treatment Resistant Depression and Brian Network Mechanism
Status: UNKNOWN
Conditions: Treatment Resistant Depression|Transcranial Magnetic Stimulation|Functional Magnetic Resonance Imaging|Event-Related Potentials
Interventions: DEVICE: repeated transcranial magnetic stimulation with real coil|DEVICE: repeated transcranial magnetic stimulation with sham coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-Week Efficacy And Safety Of Pregabalin In Treating Restless Legs Syndrome (RLS) Subjects
Status: WITHDRAWN
Conditions: Restless Legs Syndrome
Interventions: DRUG: Placebo|DRUG: pregabalin|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of PF-06826647 For Moderate To Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PF-06826647 or Placebo|DRUG: PF-06826647
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Theatrical Expressive Tasks for Children With ASD
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder
Interventions: OTHER: Expressivity protocol for children with autism|OTHER: Expressivity protocol for non-autistic children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Total Hip Replacement Performance & Assessment
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: BEHAVIORAL: Surgical simulation training in primary Total Hip Arthroplasty|OTHER: No intervention: Surgical Resident Control Group|OTHER: No Intervention: Consultant and Fellow Comparator Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1% ophthalmic suspension|DRUG: Azopt 1% Ophthalmic Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT