pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PracticeGround: Transforming Training and Delivery of Mental Health EBPs
Status: COMPLETED
Conditions: Depression|Insomnia|Suicide
Interventions: BEHAVIORAL: Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality|BEHAVIORAL: Care-as-Usual Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Comparison Between White Light Endoscopy and Bright Narrow Band Imaging in the Diagnosis of Right Sided Colonic Polyps in Asymptomatic Subjects Undergoing Screening Colonoscopy
Status: RECRUITING
Conditions: Adenoma Colon
Interventions: DIAGNOSTIC_TEST: WLE first, then B-NBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Long-Term Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
Status: COMPLETED
Conditions: Spinocerebellar Degeneration
Interventions: DRUG: KPS-0373, High dose|DRUG: KPS-0373, Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Imaging Ahmed Glaucoma Tubes With a Pericardial Graft and Tissue Glue or Partial-Thickness Scleral Flap and Sutures
Status: UNKNOWN
Conditions: Advanced Glaucoma|Failed Trabeculectomies
Interventions: PROCEDURE: Pericardial graft & tissue glue|PROCEDURE: scleral flap & sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Eloxatin and Alimta in Combination With Bevacizumab in Advanced Non-Squamous NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab, Oxaliplatin, Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovations in HIV Testing (TI)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DIAGNOSTIC_TEST: Oraquick HIV Self Test - Choice|DIAGNOSTIC_TEST: Atomo HIV Self Test - Choice|DIAGNOSTIC_TEST: Oraquick HIV Self Test and Atomo HIV Self Test - Both
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Cancer|Prostatic Neoplasms|Prostate Cancer|Prostatic Cancer|Prostate Neoplasms
Interventions: DRUG: 18F-NaF|DRUG: 18F-DCFPyL|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: PROCEDURE: Lung Surgery|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Low Dose Magnesium Sulfate in Anesthesia for Toxic Goiter Resection
Status: COMPLETED
Conditions: Haemodynamic Stability
Interventions: DRUG: MgSO4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Cutaneous Lupus Erythematosus|Sjogren's Syndrome|Systemic Sclerosis|Polymyositis|Dermatomyositis
Interventions: DRUG: VIB7734|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory and Cognitive Outcomes of Robotic Exercises in Stroke (SCORES)
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Robotic Rehabilitation of the upper limb|OTHER: Conventional Rehabilitation of the upper limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Functional Status in Older Adults Treated With L-Carnitine
Status: UNKNOWN
Conditions: Carnitine; Muscle|Functional Status|Old Age; Debility
Interventions: DRUG: L Carnitine|BEHAVIORAL: Supervised exercise|DRUG: Placebos|BEHAVIORAL: Exercise at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Microprocessor-Controlled Prosthetic Knee Evaluation
Status: RECRUITING
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: microprocessor-controlled knee (MPK) assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estrogen, HDL, and Coronary Heart Disease in Women
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Coronary Arteriosclerosis
Interventions: DRUG: Estrogens, Conjugated (USP)|DRUG: Medroxyprogesterone 17-Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Outcomes of Prophylaxis With Emicizumab in Children With Severe Hemophilia A in Ivory Coast
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Prophylaxis with Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Oral WCK 2349
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: WCK 2349 Oral|OTHER: Placebo Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Theta-Burst-Stimulation in Early Rehabilitation of Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Magstim Super Rapid2 System, intermittent theta-burst-stimulation (iTBS) protocol|DEVICE: Magstim Super Rapid2 System, sham-stimulation (in iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection
Status: TERMINATED
Conditions: Prosthetic Joint Infections of Hip|Prosthetic Joint Infections of Knee|Infected Spacers
Interventions: DRUG: CEM-102|DRUG: IV or Oral standard of care antibiotics|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Department Probiotic Treatment of Pediatric Gastroenteritis
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: DRUG: Placebo|DRUG: Lacidofil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tai Chi After Pulmonary Rehabilitation in Patients With COPD: A Randomized Trial
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Tai Chi|BEHAVIORAL: Group Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: STYLE - Symbicort Single Inhaler Therapy vs Conventional Therapy in Treatment of Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol Turbuhaler vs Conventional Best Asthma Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ALZT-OP1 Combination Therapy in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ALZT-OP1a|DRUG: ALZT-OP1b|DEVICE: Dry Powder Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Utility of ESWT in Restoring Hand Function of Patients With Nerve Injury and Hypertrophic Scars Due to Burns
Status: RECRUITING
Conditions: Hand Injuries|Extracorporeal Shock Wave Therapy|Burns
Interventions: OTHER: Extracorporeal shock wave therapy (ESWT)|OTHER: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Risk Factors for Pancreatic Fistula Grade C After Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Disease of Pancreatic Head or Periampullary Lesions to Require Pancreaticoduodenectomy
Interventions: PROCEDURE: pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Meningococcal B Vaccine and ACWY Conjugate Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Meningococcal Meningitis, Serogroup A|Meningococcal Meningitis, Serogroup B|Meningococcal Meningitis, Serogroup C|Meningococcal Meningitis, Serogroup Y|Meningococcal Meningitis, Serogroup W
Interventions: DRUG: meningococcal B vaccine & meningococcal ACYW conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)
Status: COMPLETED
Conditions: Prurigo Nodularis
Interventions: DRUG: serlopitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Demographic, Mental, and Physical Activity Profiles Towards Burnout in Frontline Healthcare Workers Facing COVID-19 Pandemics in Dr. Soetomo General Hospital Surabaya
Status: COMPLETED
Conditions: Burnout, Psychological|Anxiety
Interventions: OTHER: Zumba dance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal Fentanyl And Renal Colic
Status: COMPLETED
Conditions: Acute Renal Colic
Interventions: DRUG: FENTANYL|DRUG: Ketorolac Tromethamine AND morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epi-on PiXL for the Treatment of Progressive Keratoconus.
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus|Corneal Crosslinking|Corneal Densitometry|Scheimpflug Photography|Corneal Disorder|Eye Diseases
Interventions: PROCEDURE: Epi-on PiXL in high oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ralfinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Part A: In Patients With Chronic Liver Diseases, LAENNEC (Human Placenta Hydrolysate) is to Assess Safety and Tolerability After the Doses of Doses. Part B: Part A, it is to Determine the Optimal Dose by Evaluating Two Capacity and Placebo Groups.
Status: UNKNOWN
Conditions: Chronic Liver Disease
Interventions: BIOLOGICAL: LAENNEC (Human Placenta Hydrolysate)|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Child Follow-up in Women Treated With Conventional IVF or ICSI
Status: COMPLETED
Conditions: Conventional IVF, ICSI
Interventions: OTHER: Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3|OTHER: Physical development and General Health|OTHER: Developmental Red flags
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrative Cognitive-Affective Therapy for Adolescent Eating Disorders
Status: COMPLETED
Conditions: Eating Disorder|Emotional Disorder
Interventions: BEHAVIORAL: Integrative cognitive-affective therapy for adolescents (ICAT-A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Oliceridine|DRUG: Placebo|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Tolerability of RGL-193 in Patients With Advanced Parkinson's Disease
Status: RECRUITING
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: RGL-193（low-dose）|DRUG: RGL-193（high-dose）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of KT and PG on UE Lymphedema and Functional Disability After Mastectomy
Status: RECRUITING
Conditions: Lymphedema of Upper Limb
Interventions: OTHER: Effect of kinesio taping on upper limb lymphedema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Different Doses of REGN17092 Are Safe in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: REGN17092|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension and Healthy Controls
Interventions: BEHAVIORAL: high sodium diet|BEHAVIORAL: Low Sodium Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Clinical Study of Stent Versus Direct Atherectomy Versus Angioplasty to Treat Lower Limb In-stent Restenosis
Status: UNKNOWN
Conditions: Atherosclerosis|In-stent Arterial Restenosis
Interventions: DEVICE: plaque excision system|DEVICE: stent|DEVICE: Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing Two Models of a Travoprost Intraocular Implant
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: COMBINATION_PRODUCT: G2-TR intraocular implant containing travoprost|DRUG: Sham surgery + active-comparator eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Blom Low Profile Voice Inner Cannula and the Passy-Muir One-Way Tracheotomy Tube Speaking Valve on Voice Production, Speech Intelligibility, and Biomechanical Swallowing Behavior
Status: COMPLETED
Conditions: Mechanical Complication of Tracheostomy
Interventions: PROCEDURE: Blom Low Profile Voice Cannula/Passty-Muir Speaking Valves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Test the Efficacy and Safety of ACYC to Treat Moderate to Severe Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: ACYC|DRUG: ACYC vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OPTI - DOSE: Optimal Dosing of Oral Anticancer Drugs in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma|Ovarian Carcinoma|Thyroid Carcinoma|Breast Carcinoma|Endometrium Carcinoma
Interventions: DRUG: Olaparib|DRUG: Lenvatinib|DRUG: Sunitinib|DRUG: Palbociclib|DRUG: Pazopanib|DRUG: Olaparib|DRUG: Lenvatinib|DRUG: Sunitinib|DRUG: Palbociclib|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: JNJ-70033093 25 mg|DRUG: JNJ-70033093 50 mg|DRUG: JNJ-70033093 100 mg|DRUG: JNJ-70033093 200 mg|DRUG: Placebo|DRUG: Enoxaparin 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Rebaudioside A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants
Status: COMPLETED
Conditions: Low Birth Weight
Interventions: DIETARY_SUPPLEMENT: Probiotic supplementation (Lactobacillus rhamnosus GG and Bifidobacterium infantis)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Effect of Treatment With Estradiol Vaginal Tablets on Recurrent Urinary Tract Infections in Post-menopausal Women
Status: TERMINATED
Conditions: Menopause|Urinary Infections
Interventions: DRUG: estradiol, 25 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: CVL-231 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT
Status: RECRUITING
Conditions: TDM of 5-FU|Pharmacokinetic Observational Study
Interventions: DRUG: Extra blood samples for determining exposure to 5-FU
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: prednisone|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Carcinoma|Metastatic Colon Adenocarcinoma|Metastatic Rectal Adenocarcinoma|Recurrent Colon Adenocarcinoma|Recurrent Colorectal Adenocarcinoma|Recurrent Rectal Adenocarcinoma|Stage III Colon Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Colon Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Rectal Cancer AJCC v8|Stage IIIC Colon Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IV Colon Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Rectal Cancer AJCC v8|Stage IVB Colon Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Rectal Cancer AJCC v8|Stage IVC Colon Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Stage IVC Rectal Cancer AJCC v8|Unresectable Colon Adenocarcinoma|Unresectable Colorectal Carcinoma|Unresectable Rectal Adenocarcinoma
Interventions: DRUG: Irinotecan|BIOLOGICAL: Bevacizumab|DRUG: Trifluridine and Tipiracil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of 68-Ga-prostate Specific Membrane Antigen (PSMA)-Positron Emission Tomograph (PET) and Early Prostatic Specific Antigen (PSA) Kinetics During Salvage Radiotherapy for Personalizing the Management of Men With Relapse of Prostate Cancer After Radical Prostatectomy
Status: COMPLETED
Conditions: Relapsed Prostate Cancer
Interventions: RADIATION: External radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Non-invasive Device for Alleviation of Parkinson's Disease Symptoms
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Electro-stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: hu14.18-IL2|DRUG: hu14.18-IL2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock
Status: RECRUITING
Conditions: Cardiogenic Shock|Mitral Regurgitation
Interventions: DEVICE: Transcatheter edge-to-edge repair|OTHER: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes
Status: COMPLETED
Conditions: PreDiabetes|Blood Glucose, High
Interventions: DIETARY_SUPPLEMENT: Cinnamon|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Smoking-Cessation and Stimulant Treatment (S-CAST)
Status: COMPLETED
Conditions: Cocaine Dependence|Methamphetamine Dependence|Nicotine Dependence
Interventions: OTHER: Smoking-cessation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Study of Changes in [11C]AZ14132516 Uptake Following Administration of AZD7798 to Healthy Participants and Patients With Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: AZD7798|DRUG: [11C]AZ14132516
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis of the Knee
Interventions: DRUG: Placebo|DRUG: Cannabidiol (CBD)|DRUG: Tetrahydrocannabinol (Marinol® or generic equivalent (e.g., dronabinol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: BIOLOGICAL: B244|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Psychoeducational Intervention on Expectations and Coping in Young Women Exposed to a High HBOC Risk
Status: TERMINATED
Conditions: Hereditary Breast and Ovarian Cancer Syndrome
Interventions: BEHAVIORAL: psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration.
Status: COMPLETED
Conditions: Peripheral Nerve Injuries|Sensory Deficit|Digital Nerve Lesion
Interventions: PROCEDURE: Electrical Stimulation|PROCEDURE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREMs on PROMs in Breast Disease (PREMs_PROMs)
Status: COMPLETED
Conditions: Breast Disease|Breast Cancer|Breast Neoplasms
Interventions: OTHER: e-PROMS|OTHER: p-PROMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Erector Spinae Plane Block in Congenital Heart Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease in Children|Neurologic Complication
Interventions: OTHER: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Wireless Capsule Endoscopy in the Evaluation of Obscure Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Obscure Gastrointestinal Bleeding (Occult or Overt)
Interventions: OTHER: Capsule endoscopy|OTHER: Dedicated small bowel contrast radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of Gallium-68-tilmanocept PET/CT for Sentinel Lymph Node Detection in Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Gallium-68-tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Therapy With Thalidomide After Curative Resection of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Recurrence
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Value of Passive Leg Raise Induced Changes in Carotid Artery Flow Time to Predict Fluid Responsiveness in Critically Ill Patients
Status: COMPLETED
Conditions: Fluid Responsiveness|Carotid Artery Flow Time|Passive Leg Raise
Interventions: OTHER: Carotid Doppler Measurement in response to passive leg raise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Different Doses of the Vitamin B12 on Recurrent Aphthous Stomatitis
Status: TERMINATED
Conditions: Recurrent Aphthous Stomatitis
Interventions: DRUG: vitamin B12 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The MUFFIN-PTS Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Thrombotic Syndrome
Interventions: DRUG: Micronized Purified Flavonoid Fraction|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrin Alpha-v-Beta and [18F]-R01-MG-F2 PET/CT in Measuring Response in Patients With Pancreatic Cancer and Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subject|Pancreatic Carcinoma
Interventions: DIAGNOSTIC_TEST: Computed Tomography|OTHER: Laboratory Biomarker Analysis|DIAGNOSTIC_TEST: PET/MRI scan|DRUG: [18F]FP-R01-MG-F2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Neo-Adjuvant Treatment With Palbociclib: Effect on Ki67 and Apoptosis Before, During and After Treatment "
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Palbociclib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Dimethyltryptamine in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dimethyltryptamine (DMT)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Remifentanil Boluses on Hemodynamics in Skull Pin Insertion
Status: COMPLETED
Conditions: Skull Pin Insertion|Short Duration Analgesia
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Dexamethasone, Thalidomide and Lenalidomide for Subjects With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: dexamethasone|DRUG: thalidomide|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perifosine in Treating Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Recurrent Adult Soft Tissue Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: perifosine|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib Plus FOLFOX In Patients With Solid Tumors
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasms
Interventions: DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX|DRUG: sunitinib + FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Oestradiol Suppression: Zoladex 10.8mg/3 Month vs. 3.6mg/Month in ER +ve EBC Pre-menopausal Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Goserelin acetate|DRUG: Goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Mifepristone Tablets in the Treatment of Symptomatic Uterine Fibroids With Safety and Efficacy
Status: TERMINATED
Conditions: Uterine Fibroid
Interventions: DRUG: Mifepristone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: Xanthine Oxidase Inhibitor|DRUG: nonsteroidal anti-inflammatory drug
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in the US Based on Pharmacy and Medical Claims That Compares How Well Stiolto® and Trelegy® Work in People With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Trelegy Ellipta|DEVICE: Stiolto Respimat|DRUG: Tiotropium + Olodaterol (5/5 mcg)|DRUG: Fluticasone Furoate + Umeclidinium + Vilanterol (100/62.5/25 mcg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Mobilization After Volar Plate Osteosynthesis of Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: DEVICE: Removable splint "omni med", Fischer Medical Aps, DK-2800 Lyngby, Denmark
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3,3'-Diindolylmethane in Patients With Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: SLE
Interventions: DRUG: BR-DIM|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an E-intervention on MHBC for Chinese Cardiac Patients in Home-based Rehabilitation
Status: COMPLETED
Conditions: Cardiac Rehabilitation|Physical Activity|Fruit and Vegetable Intake
Interventions: BEHAVIORAL: E-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retzius-sparing Technique in Robotic-assisted Radical Prostatectomy
Status: UNKNOWN
Conditions: Cancer of Prostate|Prostate Adenocarcinoma|Urinary Incontinence,Stress|Erectile Dysfunction Following Radical Prostatectomy
Interventions: PROCEDURE: Retzius-repairing robot-assisted radical prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Ketamine Combine Propofol vs Propofol Anesthesia in Schizophrenia Electroconvulsive Therapy
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Propofol|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: lamivudine|DRUG: Telbivudine|DRUG: Enticavir|DRUG: Adefovir Dipivoxil Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C] NKTR-118
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diet Composition and Cardiometabolic Risk Reduction in Adults With SCI
Status: COMPLETED
Conditions: Obesity|Spinal Cord Injuries|Diabetes
Interventions: BEHAVIORAL: eHealth Behavioral Lifestyle Intervention Device: Telecoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HeartSpare Study (Stage I)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Voluntary deep-inspiratory breath hold|PROCEDURE: Active-breathing-controlled deep-inspiratory breathhold|PROCEDURE: Prone treatment|DEVICE: Active-breathing-controlled deep-inspiratory breathhold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fermented Rice Flour for the Treatment of Atopic Dermatitis: Randomized, Double-blind Controlled Trial
Status: UNKNOWN
Conditions: Dermatitis, Atopic|Child|Infant
Interventions: DIETARY_SUPPLEMENT: Fermented rice|DIETARY_SUPPLEMENT: Maltodextrins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consolidating Tools for Outcomes in Resuscitation
Status: UNKNOWN
Conditions: Cardiac Arrest|Cardiopulmonary Resuscitation|Simulation|Education
Interventions: DEVICE: Knowledge-based cognitive aid|DEVICE: Cognitive aids with roles defined (CARD)|DEVICE: Integrated cognitive aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of TQC2731 Injection in Patients With Severe Asthma.
Status: RECRUITING
Conditions: Severe Asthma
Interventions: DRUG: TQC2731 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Status: COMPLETED
Conditions: Tooth Whitening|Sensitivity
Interventions: PROCEDURE: Selection and preparation of the volunteers|PROCEDURE: Evaluation of the tooth color|PROCEDURE: Relative isolation|PROCEDURE: Gingival protection barrier|PROCEDURE: Application of desensitizing gel|DRUG: Hydrogen peroxide|PROCEDURE: Used a dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: SA53-OS (phase 1)|DRUG: SA53-OS (phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: simvastatin (+) ezetimibe|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: GDC-0449
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Prisma on Donor Site Pain
Status: COMPLETED
Conditions: Skin Graft Disorder|Donor Site Complication
Interventions: DEVICE: Promogran Prisma|DEVICE: Standard of care (SOC) dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediabetes, Prehypertension and Vitamin D Supplementation - A Practice Based Clinical Intervention Pilot Study
Status: TERMINATED
Conditions: Prediabetes|Prehypertension
Interventions: OTHER: Vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)
Status: RECRUITING
Conditions: Solid Tumor|Advanced Solid Tumor|Locally Advanced Solid Tumor|Colon Rectal Cancer|Gastric Cancer|Pancreatic Cancer|Bile Duct Cancer|Hepatocarcinoma|Breast Cancer|Ovarian Cancer|Endometrial Cancer|Cervical Cancer|Vulva Cancer|Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Risk Factor
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study C3S : Comparison Among Healthy Subject
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DEVICE: Comparative standard echocardiography between two devices : Vivid 9 General Electric and Epiq 7 Philips
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tempus Priority Study: A Pan-tumor Observational Study
Status: RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Bladder Cancer|Lung Cancer|Brain Cancer|Pancreatic Cancer|Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer|Cancer of Liver|Cancer of Colon|Cancer of Head and Neck|Cancer of Stomach|Cancer of Gastrointestinal Tract|Cancer of Rectum|Cancer of Esophagus|Cancer of Skin|Cancer of Cervix|Cancer of Kidney|Cancer of Larynx|Cancer of Endometrium|Cancer of the Bile Duct|Cancer of Vulva|Cancer of Bone and Connective Tissue|Leukemia|Lymphoma|Spinal Cord Cancer
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion
Status: UNKNOWN
Conditions: Opioid Use|Spine Fusion
Interventions: BEHAVIORAL: Spinal Fusion Preoperative Opioid Taper|OTHER: Non-taper Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Juvenile Detention to Community Life
Status: COMPLETED
Conditions: Substance Use|Delinquency|Risk for HIV Infection
Interventions: BEHAVIORAL: Multidimensional Family Therapy Cross-Systems|BEHAVIORAL: Enhanced Services as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scooter Board Activities on Neck Control and Dysphagia in Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy (CP)
Interventions: OTHER: Scooter Board Activities|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin Lymphomas
Status: COMPLETED
Conditions: Follicular Lymphoma|Small Lymphocytic Lymphoma|Lymphoplasmacytic Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Clinical Trial Evaluating the Impact of Vinegar on High Density Lipoprotein
Status: COMPLETED
Conditions: Cholesterol, HDL
Interventions: DIETARY_SUPPLEMENT: Vinegar|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Niclosamide in Moderate and Severe Hospitalized Coronavirus-19 (COVID-19) Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Niclosamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
Status: COMPLETED
Conditions: Post-Operative Pain, Chronic|Necrotic Pulp
Interventions: DIETARY_SUPPLEMENT: propolis|DRUG: Calcium Hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Low-carbohydrate/High-fat Diet on Glucose Tolerance and Lipid Profile in Lean, Healthy Women
Status: COMPLETED
Conditions: Insulin Sensitivity|Weight
Interventions: OTHER: LCHF diet and a bout of exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)
Status: COMPLETED
Conditions: Syncope|Syncope, Vasovagal|Ambulatory Blood Pressure Monitoring|Antihypertensive Drugs|Orthostatic Hypotension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inosine Reverse Chemo Resistance in Triple Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Inosine|DRUG: Taxane/Anthracycline/Eribulin Mesylate/Vinorelbine/Capecitabine/Carboplatin/UTD1/platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea, Coronary Atherosclerosis and Heart Failure in Diabetes Patients With Nephropathy
Status: COMPLETED
Conditions: Sleep Apnea|Diabetic Nephropathy Type 2|Coronary Atheroscleroses|Heart Insufficiency|Arterial Stiffness|Kidney Diseases|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Multi-Modality Imaging in Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Hematologic Malignancy
Interventions: RADIATION: FLT PET/CT|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness
Status: UNKNOWN
Conditions: Chronic Mental Illness|Major Depression|Schizophrenia|Bipolar Disorder
Interventions: DEVICE: My Coach Connect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH