pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Metabolism Informed Smoking Treatment: The MIST RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking
Interventions: BEHAVIORAL: Post-discharge automated phone calls (IVR) with option to connect with a tobacco coach.|DRUG: Nicotine Replacement Therapy|DRUG: Varenicline|OTHER: Metabolism Informed Smoking Treatment (Nicotine metabolite ratio (NMR)-based selection of pharmacotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling for Spasticity in Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Dry needling|OTHER: Physical Therapy|DEVICE: stainless steel needles (0.3mm x 50mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Alpha1-antitrypsin Deficiency
Interventions: BIOLOGICAL: ARALAST NP 60 mg/kg|BIOLOGICAL: ARALAST NP 120 mg/kg|BIOLOGICAL: GLASSIA 60 mg/kg|BIOLOGICAL: GLASSIA 120 mg/kg|BIOLOGICAL: Human Albumin 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypnosis Antenatal Training for Childbirth (HATCh): a Randomised Controlled Trial
Status: COMPLETED
Conditions: Pregnancy|Labor
Interventions: BEHAVIORAL: antenatal hypnosis + audio compact disc on hypnosis|BEHAVIORAL: Audio compact disc on hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine for Thrombolysis in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Electro Dry Needling Versus Dry Needling in Levator Scapulae Syndrome
Status: NOT_YET_RECRUITING
Conditions: Neck Syndrome
Interventions: PROCEDURE: Electro Dry Needling|PROCEDURE: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain
Status: COMPLETED
Conditions: Sprain|Strain
Interventions: DRUG: Ketoprofen Topical Patch 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden.
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Chemotherapy Effect
Interventions: DRUG: Floxuridine|PROCEDURE: Liver Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure
Status: RECRUITING
Conditions: Schizophrenia and Related Disorders|Major Depressive Disorder|Bipolar Depression
Interventions: DRUG: Clozapine|DRUG: Esketamine Nasal Product|DRUG: Escitalopram|DRUG: Sertraline|DRUG: Venlafaxine|DRUG: Lithium|DRUG: Valproate acid|DRUG: Quetiapine|DRUG: Second-line Antidepressants|DRUG: Second-line Antipsychotics|DRUG: Ketamine Hydrochloride|DRUG: Esketamine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)
Status: RECRUITING
Conditions: Insomnia|Post Traumatic Stress Disorder|Anxiety Disorders|Depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing a Cellulose Dressing to Two Standard of Care Dressings in Treating Split Thickness Donor Sites in Burn and Wound Patients.
Status: COMPLETED
Conditions: Donor Sites|Wound Heal|Wound Drainage|Pain Management
Interventions: DEVICE: NovaDress|DEVICE: Mepilex Ag|DEVICE: Xeroform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aspirin and Low Molecular Weight Heparin in IVF Outcome.
Status: UNKNOWN
Conditions: To Investigate the Effects of Low Dose Aspirin and Low Molecular Weight Heparin in IVF Out Come
Interventions: DRUG: Low molecular weight heparin|DRUG: Low dose aspirin|DRUG: Heparin & aspirin|OTHER: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ECG-I Phenotyping of Persistent AF Based on Driver Distribution to Predict Response to Pulmonary Vein Isolation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: ECG-I mapping and PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and Best Supportive Care Versus Placebo and Best Supportive Care in Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Placebo|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tegoprazan|DRUG: Naproxen|DRUG: Aceclofenac|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Garlic Extracts on Changes in Blood Flow Velocity in the Carotid Artery
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Garlic extracts|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phage Therapy in Prosthetic Joint Infection Due to Staphylococcus Aureus Treated With DAIR.
Status: RECRUITING
Conditions: Infection of Total Hip Joint Prosthesis|Infection of Total Knee Joint Prosthesis
Interventions: BIOLOGICAL: Anti-Staphylococcus aureus Bacteriophages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy vs Remote Exercise for Knee Pain Due to Osteoarthritis (OA)
Status: RECRUITING
Conditions: Knee Osteoarthritis|Chronic Pain
Interventions: OTHER: Technology-implemented exercise therapy|OTHER: Traditional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Spondylotic Myelopathy - Cost Observational Surgical Trial
Status: COMPLETED
Conditions: Cervical Spondylosis With Myelopathy
Interventions: PROCEDURE: ACDF|PROCEDURE: Posterior Cervical Fusion|PROCEDURE: Cervical Laminoplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Investigation to Evaluate the Safety and Performance of ConnettivinaBio Plus Cream Compared to ConnettivinaBio Cream in the Management of Wounds in Patients at High Risk of Infection
Status: RECRUITING
Conditions: Wounds
Interventions: DEVICE: ConnettivinaBio Plus cream|DEVICE: ConnettivinaBio cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of the Effects and Clinical Outcomes of CH2 Vaginal Gel Versus Placebo on CIN1
Status: NOT_YET_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Human Papillomavirus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation
Status: COMPLETED
Conditions: COVID-19|Sars-CoV2|Pneumonia
Interventions: DRUG: Mavrilimumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Lactobacillus Paracasei PS23 on Workplace-related Stress Symptoms Among Office Workers
Status: TERMINATED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PEERS® for Italy, a Study on Social Skills Intervention for Adolescents With Autism Spectrum Disorder (ASD).
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Program for the Education and Enrichment of Relational Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain Participants
Status: COMPLETED
Conditions: Pain|Low Back Pain|Back Pain|Osteoarthritis, Knee
Interventions: DRUG: Tapentadol Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Daily Intake of Whole Grain Barley or Oats on Biomarkers of Cardiovascular Disease
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Daily ingestion of whole grain barley and oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gastrointestinal Hormonal Regulation of Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass|DIETARY_SUPPLEMENT: Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma
Status: COMPLETED
Conditions: Glioblastoma|Malignant Glioma|Medulloblastoma Recurrent|Pediatric Glioblastoma Multiforme|Pediatric Brain Tumor, Recurrent|Pediatric Brain Tumor
Interventions: BIOLOGICAL: CMV-DCs with GM-CSF|BIOLOGICAL: Td (tetanus toxoid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Relationship Between Anti-PD-1 Exposure and Tumour VOLUME in Patients Treated for Classical HODgkin's Lymphoma.
Status: TERMINATED
Conditions: Hodgkin Lymphoma
Interventions: OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Periarticular Infiltration Vs Posterior Periarticular Infiltration Plus PENG Block for Hip Analgesia
Status: RECRUITING
Conditions: Hip Osteoarthritis|Postoperative Pain
Interventions: PROCEDURE: Periarticular Local Anesthetic Infiltration|PROCEDURE: Posterior Periarticular Local Anesthetic Infiltration plus Pericapsular Nerve Group Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optoacoustic Images Versus Imagio® Ultrasound
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Reader Study - Imagio Ultrasound|DEVICE: Reader Study Imagio Ultrasound + Optoacoustic Imaging|DEVICE: Mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PIEB-PCEA vs CEI-PCEA for Abdominal Oncological Surgery. A Randomized Prospective Clinical Trial
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Programmed intermittent epidural bolus application (PIEB)|PROCEDURE: Continous epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study Evaluating Extended Release Ropinirole XL (Formerly Referred to as Ropinirole CR) in Patients Who Already Completed Either Study 167 or 164
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Ropinirole XL (formerly CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration With Oscillating Expiratory Pressure
Status: ACTIVE_NOT_RECRUITING
Conditions: Facial Pain
Interventions: DEVICE: SinuSonic|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbosacral Erector Spinae Plane Block Versus Psoas Muscle Compartment With Sciatic Nerve Block for Anesthesia for Unilateral Lower Limb Operations in Critically Ill Patients
Status: RECRUITING
Conditions: Lumbosacral|Erector Spinae Plane Block|Psoas Muscle Compartment Block|Sciatic Nerve Block|Anesthesia|Unilateral|Lower Limb|Critically Ill Patients
Interventions: DRUG: Lumbosacral Erector Spinae Plane Block|DRUG: Psoas Muscle Compartment With Sciatic Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy, Safety and Tolerability of Selomax With Its Individual Components
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: Metoprolol XL 50mg + Amlodipine 5mg|DRUG: Metoprolol XL 25 mg + Amlodipine 2.5mg|DRUG: Metoprolol XL 50mg|DRUG: Metoprolol XL 25 mg|DRUG: Amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted BEACOPP Variants in Patients With Newly Diagnosed Advanced Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Procarbazine|DRUG: Dexamethasone|DRUG: Dacarbazine|DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer
Status: RECRUITING
Conditions: Lung Adenocarcinoma
Interventions: DRUG: Alpha-methyl-4-deoxy-4-[(18)F]fluoro-D-glucopyranoside|PROCEDURE: Computed Tomography|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness
Status: COMPLETED
Conditions: Vestibular Migraine|Chronic Subjective Dizziness
Interventions: DRUG: Verapamil|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Antiviral Activity of IDX184 in Combination With Pegylated Interferon and Ribavirin for 12 Weeks (MK-2355-005)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: IDX184|BIOLOGICAL: Peginterferon alfa-2a (Peg-IFN)|DRUG: Ribavirin (RBV)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Topical DLQ01 in the Treatment of Androgenetic Alopecia (AGA) in Men
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: prostaglandin F2a analogue in vehicle solution high dose|DRUG: prostaglandin F2a analogue in vehicle solution low dose|DRUG: active ingredient-free vehicle solution to DLQ01|DRUG: Minoxidil 5% Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Office Hysteroscopy in Women Using Progesterone-only Contraception (POC)
Status: COMPLETED
Conditions: Fallopian Tube Peristalsis and Patency|Endometrial Pattern
Interventions: DIAGNOSTIC_TEST: Darwish test (office hysteroscopic bubble suction and tubal peristalsis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Impact of Nitrous Oxide on PONV in Breast Surgeries
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: nitrous oxide anesthesia|DRUG: air anesthesia|DEVICE: laryngeal mask airway (LMA Supreme Size 3/4|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation
Status: ENROLLING_BY_INVITATION
Conditions: Radiculopathy, Lumbosacral Region|Radiculopathy Lumbar
Interventions: RADIATION: High intensity laser therapy|OTHER: Motor control exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Airway Facilitates a Safe and Smooth Emergence From Anesthesia in Patients Undergoing Craniotomy
Status: COMPLETED
Conditions: Complications, Pulmonary
Interventions: DEVICE: Ambu® AuraOnce™ Disposable Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: NR600 System Retinal Prosthesis for Patients With Retinal Degenerative Diseases
Status: TERMINATED
Conditions: Retinitis Pigmentosa|Retinal Degeneration
Interventions: DEVICE: Retinal surgery with implantation of epi-retinal device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Precision rTMS for Language Recovery in Patients After Ischemic Stroke: a Multi-center RCT
Status: RECRUITING
Conditions: Stroke, Ischemic|Aphasia
Interventions: DEVICE: active cTBS|DEVICE: sham cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Bilirubin Measurements in Neonates Post Phototherapy
Status: UNKNOWN
Conditions: Jaundice, Neonatal
Interventions: DEVICE: Transcutaneous Bilirubin Meter - 'Bilimeter'
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RSA and Clinical Comparison of Anatomical and Mechanical Alignment in Total Knee Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Personal Satisfaction|Genu Varum
Interventions: PROCEDURE: Anatomical TKA|PROCEDURE: Mechanical TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can a Modified Fat Diet With Low Glycaemic Load Improve Insulin Sensitivity and Inflammatory Mediators in Overweight People With Chronic Heart Failure?
Status: UNKNOWN
Conditions: Heart Failure
Interventions: BEHAVIORAL: High mono-unsaturated fat/low carbohydrate diet|BEHAVIORAL: High carbohydrate/low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study the Safety and Efficacy of Probiotics Use in Premature Infants
Status: WITHDRAWN
Conditions: Infant, Premature, Diseases
Interventions: DIETARY_SUPPLEMENT: breast milk with Bifidobacterium Longum subp. Infantis R0033|DIETARY_SUPPLEMENT: breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose:
Clinical trial: Analgesic Efficacy of Rhomboid Intercostal Nerve Block for Minimal Invasive Heart Surgery
Status: RECRUITING
Conditions: Minimal Invasive Heart Surgery|Rhomboid Intercostal Nerve Block
Interventions: PROCEDURE: Rhomboid Intercostal Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Test an Approved Product in the Early Treatment of Migraine (0462-066)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK0462, rizatriptan benzoate / Duration of Treatment: 1day|DRUG: Comparator: placebo / Duration of Treatment: 1 day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tranexamic to Epsilon Aminocaproic Acid: a Prospective Analysis of Blood Conservation in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DRUG: Tranexamic Acid|DRUG: Aminocaproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy of the Video Laryngeal Mask (SaCoVLM™) in Geriatric Patients: A Comparison With a Conventional Supraglottic Airway Device (Ambu®Auragain™)
Status: RECRUITING
Conditions: Elderly|Laryngeal Mask Airway|General Anesthesia
Interventions: DEVICE: SaCoVLM™|DEVICE: Ambu®Auragain™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
Status: COMPLETED
Conditions: Smoking Reduction|Tobacco Use|Tobacco Smoking|Tomography|Lung Diseases|Lung Neoplasms
Interventions: BEHAVIORAL: Unsigned note to provider about cessation medication prescription|BEHAVIORAL: Proactive Telephone Counseling from VA Quitline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Rosuvastatin and Atorvastatin in Patients With Hyperlipidemia
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Repeat Dose Zanamivir/Placebo Via Devices Administered Twice Daily for 5 Days
Status: COMPLETED
Conditions: Influenza A Virus, H1N1 Subtype
Interventions: DRUG: Zanamivir|DRUG: Zanamivir|DRUG: Zanamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Autologous Peripheral Blood Mononuclear Cells in Diabetic Foot Patients With No-option Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia|Diabetic Foot
Interventions: DEVICE: Pall Celeris System, point of care device for human cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Thiamine Administration After Cardiac Surgery Trial
Status: COMPLETED
Conditions: Lactate Blood Increase|Thiamine Deficiency
Interventions: DRUG: Thiamine 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: RADIATION: Photodynamic Therapy|OTHER: scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Evaluate Efficacy and Safety of RP101 in Combination With Gemcitabine
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: RP101|DRUG: Gemcitabine (1000 mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cannabis, Schizophrenia and Reward: Self-Medication and Agonist Treatment?
Status: COMPLETED
Conditions: Schizophrenia|Dual Diagnosis|Psychotic Disorder|Cannabis Use Disorder
Interventions: DRUG: Marijuana|DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Understanding, Modulation and Memorization of Indicators Associated to Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: BEHAVIORAL: Leatlet + visual aid (pictogram)|BEHAVIORAL: Leaflet + no visual aid (no pictogram)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: (C2013-0302) Safety and Efficacy of Escalating Doses of SAN-300 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SAN-300 0.5 mg/kg QW|DRUG: SAN-300 1.0 mg/kg QW|DRUG: SAN-300 2.0 mg/kg QOW|DRUG: SAN-300 4.0 mg/kg QOW|DRUG: SAN-300 4.0 mg/kg QW|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Strategies to Alleviate Cardiovascular Stress in Coronary Patients During Heatwaves
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: No intervention|OTHER: Fan|OTHER: Skin Wetting|OTHER: Fan + Skin wetting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Picasso NAV High-Density Mapping Catheter for Signal Analysis of Complex Arrhythmias - First-In-Man
Status: COMPLETED
Conditions: Arrhythmias
Interventions: PROCEDURE: Ablation procedure|DEVICE: Picasso NAV Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sinus Tarsi Implant as an Adjuvant Procedure to Medial Displacement Calcaneal Osteotomy in the Treatment of Mobile Adult Acquired Flatfoot Deformity
Status: RECRUITING
Conditions: Acquired Adult Flatfoot Deformity|Flat Foot|Flexible Flatfoot
Interventions: DEVICE: ProStop, sinus tarsi implant (STI)|PROCEDURE: Conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: DRUG: Tislelizumab|DRUG: BGB-A425|DRUG: LBL-007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Reproxalap Ophthalmic Solution (0.5%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoradiation or Brachytherapy for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Endo-HDR (if randomized to this arm)|DRUG: capecitabine and IMRT (if randomized to this arm)|RADIATION: IMRT (intensity modulated radiation therapy)|DRUG: FOLFOX6|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing Impacts of Static Magnetic Fields on Peripheral Pulses and Skin Blood Flow
Status: RECRUITING
Conditions: Arterial Stiffness|Magnetic Field Exposure|Peripheral Arterial Disease
Interventions: DEVICE: magnet and sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of n-3 Polyunsaturated Fatty Acids in Patients With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DIETARY_SUPPLEMENT: n-3PUFA|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders
Status: RECRUITING
Conditions: Bipolar Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Integrated Treatment Adherence Program for Veterans (ITAP-VA)|BEHAVIORAL: Safety Assessment and Follow-up Evaluation (SAFE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil).
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: DKF-310|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Vitamin D Supplementation Among Overweight Jordanian Women With Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Hypovitaminosis D
Interventions: DRUG: 50,000 IU vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of Combining Mindfulness-Based Stress Reduction With Exercise Interventione
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BEHAVIORAL: routine health education|BEHAVIORAL: psychological nursing|BEHAVIORAL: MBSR therapy|BEHAVIORAL: exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
Status: COMPLETED
Conditions: Femoral Neck Fractures|Pertrochanteric Fracture|Bone Resorption|Bone Loss|Muscle Loss|Muscle Damage
Interventions: PROCEDURE: Surgical treatment of proximal femur fracture and blood sample test|PROCEDURE: Blood sample test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: NNC0519-0130|DRUG: Levonorgestrel + Ethinylestradiol|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral Tablet
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Viagra 50 mg tablet|DRUG: Formulation B ODT tablet 50 mg|DRUG: Formulation C ODT tablet 50 mg|DRUG: Formulation D ODT tablet 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Safety, Tolerability, and Immunogenicity of Meningococcal B Vaccine in Healthy Infants
Status: TERMINATED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: meningococcal B rLP2086 vaccine|BIOLOGICAL: Routine age appropriate childhood vaccines|BIOLOGICAL: meningococcal B rLP2086 vaccine|BIOLOGICAL: Routine age appropriate childhood vaccines|BIOLOGICAL: Routine age appropriate childhood vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection
Status: RECRUITING
Conditions: Sacroiliac Joint Dysfunction|Sacro-Iliac Spondylosis
Interventions: DRUG: Dexamethasone|DRUG: Methylprednisolone|DRUG: 2% Lidocaine HCl Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: TNP-2092 capsules|DRUG: TNP-2092 capsules placebo|DRUG: Rabeprazole sodium enteric-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Versus IV Dexmedetomidine as Adjuvant to Quadratus Lamborum Block for Pediatrics Undergoing Pyeloplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Quadratus lamborum dexmedetomidine intravenous|DRUG: Quadratus lamborum dexmedetomidine perineural group(
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computer-assisted Cognitive Rehabilitation (CACR), Placebo CACR and Psycho-stimulants in the Treatment of ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: OTHER: Computerized cognitive rehabilitation|DRUG: Ritalin|OTHER: Placebo CACR [PCACR]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment
Status: COMPLETED
Conditions: Renal Colic
Interventions: DRUG: Paracetamol+Morphine|DRUG: Dexketoprofen plus Morphine|DRUG: Placebo plus Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The ELG Analysis of Glucose a Correlational to Blood Glucose Assay
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: ELG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Trial: Bioavailability Animal vs. Plant Protein Drink
Status: RECRUITING
Conditions: Nutrition, Healthy|Leucine Sensitivity
Interventions: DIETARY_SUPPLEMENT: Consumption of protein - rich drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participants With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine|DRUG: Obinutuzumab|DRUG: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyses of Exosomes in the Cerebrospinal Fluid for Breast Cancer Patients With Suspicion of Leptomeningeal Metastasis.
Status: WITHDRAWN
Conditions: Breast Cancer|Leptomeningeal Metastasis
Interventions: PROCEDURE: Cerebrospinal fluid and blood sample collection at the initial diagnostic assessment|PROCEDURE: Cerebrospinal fluid and blood sample collection if conclusions of initial diagnostic assessment are "Lack of evidence" according to EANO-ESMO classification|PROCEDURE: Cerebrospinal fluid and blood sample collection if conclusions of initial diagnostic assessment are "confirmed", "probable" or "possible", leading to leptomeningeal metastase specific treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evolocumab in Acute Coronary Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin in the Treatment of Pregnant Women With Adenomyosis on Reducing Preterm Delivery
Status: UNKNOWN
Conditions: Adenomyosis of Uterus
Interventions: DRUG: Aspirin/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Silk and Polyester Suture on Postoperative Complications
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Silk suture|PROCEDURE: Polyester suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
Status: COMPLETED
Conditions: Pertrochanteric Fracture
Interventions: DRUG: Marcaine, Duramorph , ketorolac|DRUG: Bupivacaine (Marcaine)|DRUG: General Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of SAR240550 (BSI-201) in Combination With Gemcitabine/Carboplatin, in Patients With Metastatic Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer, Metastatic
Interventions: DRUG: Iniparib|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Shugan Jieyu Capsule in Generalized Anxiety Disorder
Status: NOT_YET_RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Shugan Jieyu Capsules|DRUG: Shugan Jieyu Capsules+Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vismodegib in Basal Cell Carcinomas (BCC) Chemoprevention
Status: TERMINATED
Conditions: Basal Cell Carcinomas
Interventions: DRUG: Vismodegib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Xinmailong Injection on Reducing Cardiovascular Toxicity in Adjuvant Chemotherapy in Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms|Cardiac Event|Chemotherapeutic Toxicity
Interventions: DRUG: Xinmailong Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Raltegravir Plus Darunavir/Ritonavir in Treatment-Naive HIV-Infected Adults
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: DRUG: Raltegravir|DRUG: Darunavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Static and Dynamic Postural Stability in Cerebral Palsy Children
Status: COMPLETED
Conditions: CP (Cerebral Palsy)|Diplegia|Hemiplegia|Postural; Defect
Interventions: PROCEDURE: no distractor control group|PROCEDURE: visual and sound attentional distractors|PROCEDURE: sound attentional distractor alone|PROCEDURE: additional cognitive task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Treatments to Improve Smoking Cessation Medication Adherence
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Adherence|Nicotine Dependence|Motivation
Interventions: DRUG: Short Term Combination Nicotine Replacement Therapy (patch + gum)|DRUG: Long Term Combination Nicotine Replacement Therapy (patch + gum)|BEHAVIORAL: Intensive Maintenance Counseling|BEHAVIORAL: Cognitive Medication Adherence Counseling (CAM)|BEHAVIORAL: Electronic Medication Monitoring Device (the Helping Hand) + Feedback|BEHAVIORAL: Automated Adherence Prompting Phone Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth to Reduce Mental Health in Family Caregivers
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue|Grief|Burden, Caregiver
Interventions: OTHER: Behavioral: Mindfulness Based Cognitive Therapy|OTHER: Behavioral: Behavior Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury
Status: RECRUITING
Conditions: Lower Limb or Combined Lower Limb and Upper Limb Spasticity Due to Stroke or Traumatic Brain Injury
Interventions: DRUG: NT 201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Telerehabilitation Methods on Pain, Functional Limitation, Muscle Strength, Balance, and Quality of Life in Patients With Knee Osteoarthritis.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Exercise Therapy via video conference|OTHER: Exercise Therapy via mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TG02 in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma
Status: COMPLETED
Conditions: Astrocytoma, Grade III|Glioblastoma
Interventions: DRUG: TG02|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Danoprevir/r + PR 12-week Triple Therapy in Treatment-Naive, Non-Cirrhotic, G1 CHC China II
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Danoprevir|DRUG: Ritonavir|DRUG: peginterferon alfa-2a|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Support Intervention in Intensive Care Units (The Four Supports Study)
Status: COMPLETED
Conditions: Physician-Family Communication in Intensive Care Units|Surrogate Decision-making for Critically Ill Patients
Interventions: BEHAVIORAL: Family Support Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab and Dexamethasone Followed by Mycophenolate Mofetil or Placebo in Patients With Immune Thrombocytopenia
Status: WITHDRAWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Rituximab|DRUG: Dexamethasone|DRUG: Mycophenolate mofetil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer
Status: COMPLETED
Conditions: Breast Cancer|Cancer Survivor|Hot Flashes|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: magnesium oxide|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: bevasiranib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT