pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tacrolimus and Thymoglobulin, as GvHD Prophylaxis in Patients Undergoing Related Donor HCT
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: DRUG: Tacrolimus and Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethiopia Antimalarial in Vivo Efficacy Study 2012
Status: COMPLETED
Conditions: Plasmodium Vivax Infection
Interventions: DRUG: Artemether-lumefantrine combination|DRUG: Primaquine|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-healing Diabetic Foot Ulcers (DFU) Treated With SoC With or Without NEOX®CORD 1K
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: OTHER: NEOX®CORD 1K|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Antidepressant Efficacy of Low Frequency rTMS as add-on
Status: WITHDRAWN
Conditions: Depression
Interventions: DEVICE: Right prefrontal low frequency rTMS|OTHER: Sham-rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trials Comparing of HD Versus 4K Laparoscopy for Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: 4K Laparoscopic Surgery|PROCEDURE: HD Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of High Dose Baclofen for Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Baclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients
Status: RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DRUG: Sintilimab|DRUG: Peg-IFNα-2b|DRUG: NAs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Study of 89Zr-DFO-YS5 in Men With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 89Zr-DFO-YS5|BIOLOGICAL: YS5 antibody|PROCEDURE: Positron Emission Tomography (PET)/Computerized tomography (CT)|PROCEDURE: Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG3067 in Healthy Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG3067 single dose|DRUG: Placebo single dose|DRUG: GLPG3067 multiple dose|DRUG: Placebo multiple dose|DRUG: GLPG3067 oral suspension|DRUG: GLPG3067 oral tablet|DRUG: GLPG3067/GLPG2222 multiple dose|DRUG: GLPG3067/GLPG2222 Placebo multiple dose|DRUG: GLPG3067/GLPG2222/GLPG2737 multiple dose|DRUG: GLPG3067/GLPG2222/GLPG2737 Placebo multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TMC207-TiDP13-C117: Interaction Study in Human Immunodeficiency Virus-type 1 (HIV-1) Infected Patients With Nevirapine (NVP)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC207; nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Localized Extraskeletal Ewing Sarcoma|Peripheral Primitive Neuroectodermal Tumor of Bone|Peripheral Primitive Neuroectodermal Tumor of Soft Tissues
Interventions: DRUG: Cyclophosphamide|DRUG: Dexrazoxane|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|DRUG: Topotecan Hydrochloride|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Citicoline and Docosahexaenoic Acid (DHA) on the Visual Function of Patients With Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DIETARY_SUPPLEMENT: Citicoline|DIETARY_SUPPLEMENT: Docosahexaenoic Acid (DHA)|DIETARY_SUPPLEMENT: Citicoline and Docosahexaenoic Acid (DHA)|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Manually Controlled Propofol Infusion and Target Controlled Infusion in Children
Status: COMPLETED
Conditions: Propofol Anesthesia in Children
Interventions: DRUG: Propofol infusion via manually controlled pump.|DRUG: Propofol infusion via target controlled pump.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Lamotrigine Versus Levetiracetam in the Initial Monotherapy of Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lamotrigine|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prophylaxis of Gastric Variceal Bleed
Status: COMPLETED
Conditions: Gastric Varices
Interventions: PROCEDURE: Balloon-occluded retrograde transvenous obliteration|PROCEDURE: Endoscopic cyanoacrylate injection|DRUG: N-butyl-2-cyanoacrylate|DRUG: Lauromacrogol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|PreDiabetes|Insulin Resistance|Obesity|Nonalcoholic Steatohepatitis|Nonalcoholic Fatty Liver|Diet Modification
Interventions: BEHAVIORAL: Dietary Intervention Mediterranean Low Carbohydrate Diet|BEHAVIORAL: Dietary Intervention Standard Low Carbohydrate Diet|BEHAVIORAL: Dietary Intervention Standard Low Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pressure-controlled Versus Volume-controlled Ventilation During Protective One Lung Ventilation
Status: UNKNOWN
Conditions: Arterial Oxygenation During Protective One Lung Ventilation
Interventions: PROCEDURE: the change of ventilatory mode|PROCEDURE: the change of ventilatory mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14)
Status: ACTIVE_NOT_RECRUITING
Conditions: Light Chain (AL) Amyloidosis|CCND1 Translocation|Venetoclax
Interventions: DRUG: Venetoclax|DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Weight Reduction and Lifestyle Program in Older Adults
Status: COMPLETED
Conditions: Functional Disability|Obesity|Physical Inactivity
Interventions: BEHAVIORAL: Diet and physical activity|OTHER: Physical activity control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment
Status: COMPLETED
Conditions: Smoking Cessation|Stress|Sleep Disturbance|Nausea
Interventions: DRUG: Varenicline Pill|DRUG: Hydroxyzine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial
Status: RECRUITING
Conditions: Advanced Melanoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Melanoma of Unknown Primary|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Unresectable Acral Lentiginous Melanoma|Unresectable Melanoma|Unresectable Mucosal Melanoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|OTHER: Patient Observation|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine 2830930A Administered in Toddlers
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK2830930A|BIOLOGICAL: Synflorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First-line Maintenance of OH2 Injection for Advanced Colorectal Cancer
Status: TERMINATED
Conditions: Advanced Colorectal Carcinoma
Interventions: BIOLOGICAL: OH2|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy of Cancer With Allogeneic Blood Lymphocytes Activated With Recombinant Interleukin-2 (rIL-2) for Metastatic Solid Tumors
Status: UNKNOWN
Conditions: Tumors
Interventions: PROCEDURE: Cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Trimetazidine As a Potential Adjuvant Therapy in Acute Aluminum Phosphide Poisoning-induced Cardiotoxicity
Status: UNKNOWN
Conditions: Aluminum Phosphide Poisoning
Interventions: OTHER: standard treatment|DRUG: trimetazidine hydrochloride "metacardia" ® 20 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Shoulder Anterior Capsular Infiltration Plus Hydrodilatation With Steroid Versus Hyalase in Patients With Frozen Shoulder
Status: NOT_YET_RECRUITING
Conditions: Frozen Shoulder
Interventions: PROCEDURE: hydrodilatation with steroid in group A versus hyalase in group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PRYSHM for LGBTQIA2S+ Youth
Status: COMPLETED
Conditions: Dating Violence|Alcohol Drinking
Interventions: BEHAVIORAL: Promoting Resilient Youth with Strong Hearts and Minds (PRYSHM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity
Status: TERMINATED
Conditions: DLBCL|Neurotoxicity Syndromes
Interventions: DRUG: Defibrotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-ventilator Interaction During NIV With Helmet: a Comparison Between PSV and the New NIV NPS Software
Status: COMPLETED
Conditions: Respiratory Failure|Mechanical Ventilation Complication
Interventions: DEVICE: nPSV and PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the 2005 AMS (American Medical System) IPP (Inflatable Penile Prosthesis)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DEVICE: AMS 700 IPP with MS Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Mild COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: MIR 19 ®|COMBINATION_PRODUCT: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis
Status: TERMINATED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: COMBINATION_PRODUCT: PUR1900|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Chinese Patent Medicine Yangzhengxiaoji Capsule to Improve the Nausea of Niraparib in the Maintenance Treatment in Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Yangzheng Xiaoji|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Bioavailability and Food Effect of Veliparib Tablets Followed by an Extension in Subjects With Ovarian Cancer
Status: WITHDRAWN
Conditions: Cancer - Ovarian
Interventions: DRUG: Veliparib, capsule|DRUG: Veliparib, tablet|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics (L. Gasseri, B. Bifidum, B. Longum) on Immune and Intestinal Health in Healthy Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
Status: COMPLETED
Conditions: Myocardial Revascularization|Spinal Anesthesia|Postoperative Care|Fentanyl
Interventions: PROCEDURE: General anesthesia only|PROCEDURE: General anesthesia and Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Investigate Long-term Safety and Tolerability of Itepekimab in Participants With COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Itepekimab (SAR440340)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma:
Status: RECRUITING
Conditions: Meningioma|Radiation Toxicity
Interventions: RADIATION: Normo-fractionated intensity-modulated brain irradiation with or without stereotactic positioning|RADIATION: Hypo-fractionated stereotactic brain irradiation|RADIATION: Normo-fractionated proton therapy brain irradiation|OTHER: Cognitive assessment by a trained neuropsychologis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Cessation
Interventions: BEHAVIORAL: BecomeAnEX|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Total Knee Arthroplasty Surgical Technique on Coronal Plane Motion and PatelloFemoral Articulation
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: PROCEDURE: Gap balanced surgical technique|PROCEDURE: Measured resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Uremic Toxin Removal With a New High Flux Cellulose Triacetate Membrane
Status: COMPLETED
Conditions: Haemodialysis
Interventions: PROCEDURE: Haemodialysis with either low or high flux membranes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Insomnia in School Aged Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Insomnia Chronic|Autism Spectrum Disorder
Interventions: BEHAVIORAL: In-Person CBT for insomnia in children with autism|BEHAVIORAL: Remote CBT for insomnia in children with autism|BEHAVIORAL: Remote sleep hygiene and related education (SHARE) for insomnia in children with autism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagen Cross-linking in Infectious Keratitis Trial
Status: COMPLETED
Conditions: Infectious Keratitis|Bacterial Keratitis|Fungal Keratitis
Interventions: PROCEDURE: Collagen cross-linking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protocol in Acute Myeloid Leukemia With FLT3-ITD
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Midostaurin|DRUG: Cytarabine|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Resuscitation (CPR) Video to Enhance Advance Care Planning in Advanced Upper Gastrointestinal Cancer Patients
Status: COMPLETED
Conditions: Pancreas and Hepatobiliary Cancer Patients
Interventions: BEHAVIORAL: (CPR) video and questionnaires|BEHAVIORAL: cardiopulmonary resuscitation (CPR) narrative script and questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glucose Insulin Potassium With Intensive Insulin Therapy and (GIK2) Versus GIK Alone
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: GIK and intensive insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Spine Injuries and Disorders|Narcotic Use
Interventions: DRUG: Pre-op Multimodal analgesia (MMA) regimen + standard post-op oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Shorten Gonadotropin-releasing Hormone Agonist Therapy on the Outcome of in Vitro Fertilization-Embryo Transfer in Patients With Endometriosis
Status: UNKNOWN
Conditions: Clinical Pregnancy Rate
Interventions: DRUG: Long term GnRH-a (3.75mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Review of Safety Using Rilonacept in Preventing Gout Exacerbations (RE-SURGE)
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: Rilonacept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Beach chair (BC) and ZEEP|PROCEDURE: Reverse Trendelenburg and NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Outcomes of Immediate Breast Reconstruction (POBRAD-M)
Status: UNKNOWN
Conditions: Breast Neoplasms|Breast Diseases
Interventions: PROCEDURE: Breast reconstruction - implant and an ADM (SurgiMend)|PROCEDURE: Breast reconstruction- autologous tissue|PROCEDURE: Breast reconstruction- implant + dermal sling/LD flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Pleuropulmonary Blastoma (PPB) Treatment and Biology Registry
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleuropulmonary Blastoma
Interventions: DRUG: Vincristine|DRUG: Dactinomycin|DRUG: Cyclophosphamide|DRUG: Ifosfamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: therapeutic autologous lymphocytes|BIOLOGICAL: aldesleukin|DRUG: cyclophosphamide|PROCEDURE: biopsy|OTHER: immunohistochemistry staining method|OTHER: flow cytometry|GENETIC: polymerase chain reaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TPVB or SPSIPB in Pain Management After VATS
Status: RECRUITING
Conditions: Video-assisted Thoracoscopic Surgery|Paravertebral Block|Serratus Posterior Superior Intercostal Plane Block|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Serratus Posterior Superior Intercostal Plane Block|PROCEDURE: Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MIBG in Aging and Neurologic Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Lewy Body Disease|Dementia|Parkinsonism|Mild Cognitive Impairment|REM Sleep Behavior Disorder
Interventions: DRUG: meta-iodobenzylguanidine (MIBG) (123I)|DIAGNOSTIC_TEST: 123I-MIBG scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Nelfinavir|DRUG: Nelfinavir Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide in Combination With Decitabine in Non-Hodgkin's Lymphoma Relapsed After Chimeric Antigen Receptor
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: Chidamide|DRUG: Decitabine|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure on Pain, Anxiety and Vital Signs in Patients With Coronary Angiography
Status: UNKNOWN
Conditions: Pain|Anxiety|Vital Signs|Coronary Angiography
Interventions: BEHAVIORAL: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: CD19 CAR-T cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isolated Roux Loop Pancreaticojejunostomy Versus Pancreaticogastrostomy After Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Fistula After Pancreaticoduodenectomy
Interventions: PROCEDURE: Pancreaticogastrostomy group|PROCEDURE: Isolated Roux PJ group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Combined With Anlotinib as Re-challenge Treatment in Advanced NSCLC
Status: COMPLETED
Conditions: NSCLC Stage IV|Checkpoint Inhibitor
Interventions: DRUG: Nivolumab Combined with Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PoCUS Diagnostic Accuracy for Fecal Impaction in the Emergency Department: A Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Fecal Impaction of Colon
Interventions: OTHER: POCUS diagnostic value
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness
Status: COMPLETED
Conditions: Single Sided Deafness
Interventions: DEVICE: Cochlear Nucleus Cochlear Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Imaging for Radiotherapy Treatment Planning and Guidance for Low-Intermediate Risk Prostate Cancer (Margin)
Status: ACTIVE_NOT_RECRUITING
Conditions: Low or Intermediate Risk Prostate Cancer
Interventions: PROCEDURE: Advanced imaging for radiotherapy planning and guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malaria
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: chlorproguanil-dapsone-artesunate|DRUG: artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Platinum-Containing Chemotherapy in Patients With Advanced or Recurrent Non-Squamous Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Platinum-based chemotherapy|DRUG: Bevacizumab [Avastin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in HIp Fracture Surgery (THIF Study)
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Tranexamic acid (Exacyl)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of NanoTite Implants Placed Into Fresh Sinus-Lift Augmentation Sites (VSSL)
Status: COMPLETED
Conditions: Tooth Disease|Partial Edentulism
Interventions: DEVICE: Dental Implant (Osseotite)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4917838 (Bitopertin) in Patients With Persistent, Predominant Negative Symptoms of Schizophrenia (WN25309)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: bitopertin [RO4917838]|DRUG: bitopertin [RO4917838]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SmokefreeSGM Español Pilot, Beta Testing a Text-based Smoking Cessation Intervention for Sexual and Gender Minority(SGM) Groups Preferring Spanish Language
Status: NOT_YET_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: SmokefreeSGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Polymorphisms in Ranibizumab Treatment in Wet Age-Related Macular Degeneration (AMD)
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Ranibizumab|PROCEDURE: Ranibizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Acceptance and Commitment Therapy for Parents of Disabled Child
Status: COMPLETED
Conditions: Acceptance and Commitment Therapy|Anxiety Depression|Caregiver Burden|Public Health Nurse|Stress|Special Needs Children|Caregiver Burnout
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AML
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: IGN523
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Samarium Sm 153 Lexidronam Pentasodium and High-Dose Melphalan in Treating Patients With Multiple Myeloma Undergoing Stem Cell Transplant
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: sargramostim|DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: samarium Sm 153 lexidronam pentasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Functional Outcome and Complications After Global Unite ® Prostheses
Status: UNKNOWN
Conditions: Osteoarthritis of the Shoulder|Proximal Humeral Fracture
Interventions: PROCEDURE: Global Unite hemiarthroplasty|PROCEDURE: Global Advantage|PROCEDURE: Global FX|PROCEDURE: Global Unite total shoulder arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-electrocoagulation Retinectomy for Retinal Re-detachment in Silicone Oil Filled Eye
Status: UNKNOWN
Conditions: Retinal Detachment
Interventions: PROCEDURE: Multi-electrocoagulation retinectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Adaptations to Exercise
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: n3-PUFA|DRUG: Placebo|PROCEDURE: Biopsy|DIAGNOSTIC_TEST: Body Composition Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Patch for Myocardial Infarction COVID-19
Status: UNKNOWN
Conditions: Myocardial Infarction|Heart Diseases
Interventions: DEVICE: Heart patch seeded with autologous cardiomyocytes and amnion epithelial stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CorMatrix Cor TRICUSPID ECM Valve Replacement - Pivotal Study
Status: RECRUITING
Conditions: Tricuspid Valve Disease|Tricuspid Valve Insufficiency
Interventions: DEVICE: Tricuspid valve replacement with the Cor TRICUSPID ECM Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of N6022 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: N6022|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Coffeeberry on Mood, Motivation and Cognitive Performance
Status: COMPLETED
Conditions: Fatigue, Mental|Alertness|Mood|Motivation|Cognitive Performance
Interventions: DIETARY_SUPPLEMENT: Cherry-flavored still beverage|OTHER: Placebo cherry-flavored still beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the SPINNER Device for the Application of Wound Dressing: Treatment of Split Skin Graft Donor Sites
Status: COMPLETED
Conditions: Wound of Skin
Interventions: DEVICE: SPINNER|DEVICE: JELONET / IBU Biatain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ciclesonide vs Fluticasone Nasal Sprays in Nasal Poplyposis
Status: UNKNOWN
Conditions: Chronic Rhinosinustis With Polyps
Interventions: DRUG: Ciclesonide|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Urothelial Carcinoma|Triple Negative Breast Cancer|Non-small Cell Lung Cancer|Squamous Cell Carcinoma of Head and Neck|Hormone Receptor-positive/HER2-negative Breast Cancer
Interventions: DRUG: SBT6290|DRUG: SBT6290|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In Adults
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: meningococcal B rLP2086 vaccine candidate|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
Status: RECRUITING
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: Cefepime-zidebactam (FEP-ZID)|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exergame and Robotic Therapy Impact on Tenascin-C and Functional Outcome on Stroke Patients
Status: RECRUITING
Conditions: Stroke|Paralysis Arm
Interventions: PROCEDURE: Exergame|PROCEDURE: Robotic|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying During Labor at Term: Non-inferiority Clinical Trial
Status: COMPLETED
Conditions: Gastric Emptying|Pregnancy Vomits
Interventions: DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Orange Juice|DIETARY_SUPPLEMENT: Coffee with milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Intraoperative Bleeding
Interventions: DRUG: Tranexamic Acid standard dose|DRUG: Females Tranexamic Acid weighted dose|DRUG: Females receiving a uniform dose of TA|DRUG: Males Weighted Dose TA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Assessment of Added Diagnostic Value of Dual Energy CT Images Using Data Acquired on a Spectral Detector CT
Status: COMPLETED
Conditions: Compare Image Quality Between SDCT and Conventional CT Images of Any Tissue Lesion, Determine Optimal Monochromatic Energy Level for a Coronary Artery Image
Interventions: DEVICE: Computed Tomography scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Using 18F-FAPI PET to Evaluate Treatment Response in Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: 18F-FAPI|Pancreas Adenocarcinoma|Systemic Treatment|Pathologic Response
Interventions: DIAGNOSTIC_TEST: 18F-FAPI PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory Function
Status: COMPLETED
Conditions: Malaria|Falciparum
Interventions: DRUG: Artesunate-mefloquine|DRUG: Atovaquone-proguanil|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Proximal and Distal Adductor Canal Block in Knee Replacement Surgery
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: ADDUKTOR CANAL BLOCK|OTHER: CONTROL GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lay Health Advisors for Sexually Transmitted Disease Prevention
Status: COMPLETED
Conditions: Syphilis|Gonorrhea|Chlamydia Infections|HIV Infections
Interventions: BEHAVIORAL: HoMBReS: A lay health advisor approach to STD prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intraperitoneal Infusion of ex Vivo-cultured Allogeneic NK Cells in Recurrent Ovarian Carcinoma Patients
Status: COMPLETED
Conditions: Recurrent Ovarian Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: UCB-NK cells|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Doxorubicin Hydrochloride Liposome in Treating Women With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab + doxorubin hydrochloride liposme|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: NVX-CoV2601 co-formulated Omicron XBB.1.5 SARS-CoV-2 rS vaccine|BIOLOGICAL: Prototype/XBB.1.5 Bivalent Vaccine (5 µg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing Body Composition & Health After Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasm|Osteoporosis, Postmenopausal
Interventions: BEHAVIORAL: Resistance Exercise|BEHAVIORAL: Flexibility Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Superficial Neuromuscular Stimulation in Post-stroke Dysphagic Patients.
Status: COMPLETED
Conditions: Dysphagia|Stroke
Interventions: DEVICE: NMES (neuromuscular electrical stimulation)|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echo Doppler (ED )Score and D-dimer (DD) Level in the Evaluation of VTE Recurrence After Anticoagulant Treatment Cessation
Status: COMPLETED
Conditions: Previous Vka Treatment|Previous Proximal VTE
Interventions: OTHER: ED, DDimers and phone follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Human Papillomavirus (HPV) in 20 to 45 Year Old Chinese Women (V501-041)
Status: COMPLETED
Conditions: HPV Infections
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine|BIOLOGICAL: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Vaniprevir 300 mg|DRUG: Vaniprevir 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Atorvastatin|DRUG: Placebo atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Activities and Exercise on Sleep in Elderly Persons With Dementia
Status: COMPLETED
Conditions: Dementia|Elderly|Sleep
Interventions: BEHAVIORAL: Control Condition|BEHAVIORAL: Individualized Social Activities (ISA)|BEHAVIORAL: Physical Resistance Training and Walking (PRT/walking)|BEHAVIORAL: Combined ISA/PRT/walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Specificity of Flavor-Nutrient Learning: An fMRI Experiment
Status: COMPLETED
Conditions: Feeding Behavior|Inhibition (Psychology)
Interventions: DIETARY_SUPPLEMENT: Juice A|DIETARY_SUPPLEMENT: Juice B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Injection of Lymphocytes From Haplo-identical Donor Following Chemotherapy in Patients With High-risk Acute Myeloblastic Leukemia Not Eligible for an Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: BIOLOGICAL: DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Improve Time on Adhesive System
Status: COMPLETED
Conditions: Clinical Trial
Interventions: OTHER: Peak etch-and-rinse (P1)|OTHER: Peak applied for double time(P2X)|OTHER: Single Link etch-and-rinse (SL1)|OTHER: Single Link double time (SL2X)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma Surgery
Status: UNKNOWN
Conditions: Glaucoma|Open Angle Glaucoma
Interventions: DEVICE: ARGOS-SC suprachoroidal pressure sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Antithymocyte Globulin and Azathioprine Versus Basiliximab and Mycophenolate Mofetil in Living Donor Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Antithymocyte Immunoglobulin (Rabbit)|DRUG: Interleukin 2 Receptor Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home-Based tDCS in Children With ADHD: A Randomized, Sham-Controlled tDCS and fNIRS Study
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)|Attention Deficit Disorder (ADD)
Interventions: DEVICE: Home-based transcranial direct current (tDCS) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Conceptual Saturation of Evaluating Respiratory Symptoms (E-RS) in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Telephonic interviews|OTHER: E-RS: COPD|OTHER: Supplemental asthma items|OTHER: Daily diary|OTHER: Sociodemographic questionnaire|OTHER: Clinical questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inpatient Smokers and LDCT Screening RCT
Status: COMPLETED
Conditions: Lung Cancer|Shared Decision Making
Interventions: BEHAVIORAL: tobacco dependence/smoking cessation counseling|BEHAVIORAL: SDM|OTHER: Decision Aid|OTHER: LDCT brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Field Bedside Brain Magnetic Resonance Imaging in Pediatric Extracorporeal Membrane Oxygenation
Status: ACTIVE_NOT_RECRUITING
Conditions: Feasibility and Safety of a Low-field MRI|Acute Brain Injury|Extracorporeal Membrane Oxygenation Complication
Interventions: DEVICE: Hyperfine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Use of Radiofrequency Ablation to Eliminate Continuous Atrial Fibrillation in Patients Undergoing Mitral Valve Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Radiofrequency Catheter Ablation
Interventions: DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: FMISO-PET in Brain Tumors and SCS Effect
Status: TERMINATED
Conditions: Malignant Glioma
Interventions: DRUG: 18F-FMISO|PROCEDURE: PET without SCS|DEVICE: SCS|PROCEDURE: PET without/with SCS|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC