pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MBX 2109 (Part A)|DRUG: MBX 2109 (Part B)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Efficacy Enhancing Interviewing Techniques Study
Status: COMPLETED
Conditions: Diabetes|Depression|Anxiety|Asthma|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Self-efficacy enhancing interviewing techniques training|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Melanoma|Ocular Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for Lymphoma
Status: COMPLETED
Conditions: Hodgkin Disease|Lymphoma, Non-Hodgkin
Interventions: DRUG: Carmustine|DRUG: Etoposide phosphate|DRUG: Cytarabine|DRUG: Melphalan HCl (propylene glycol-free)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Retention in High Grade Upper Tract Urothelial Cancer
Status: NOT_YET_RECRUITING
Conditions: High Grade Urothelial Carcinoma|Bladder Cancer|Urothelial Carcinoma Bladder
Interventions: DRUG: Enfortumab vedotin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Thoracic Screw Manipulation in Patients With Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Thoracic Manipulation and Sustained Natural Apophyseal Glides and conventional therapy|OTHER: Sustained Natural Apophyseal Glides and conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming
Status: COMPLETED
Conditions: Photodamaged Skin|Skin Care
Interventions: OTHER: Topical Body Firming Moisturizer|OTHER: Body Cleanser|OTHER: Sunscreen|OTHER: Placebo Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Heart Rate Oscillations During Meditation on Plasma Biomarkers of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Belly-focus meditation|BEHAVIORAL: Belly-focus meditation with slow breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibition and Induction on the Pharmacokinetics of CC-220 in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: CC-220|DRUG: Rifampin|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy, Exercise and US Vs. Manual Therapy, Exercise and US for Medial Epicondylalgia
Status: RECRUITING
Conditions: Epicondylalgia
Interventions: OTHER: Electric Dry Needling, Manual Therapy, Exercise and Ultrasound|OTHER: Manual Therapy, Exercise and Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Before and After Nephrectomy of Locally Advanced or Metastatic Renal Cell Carcinoma Treated With Everolimus
Status: COMPLETED
Conditions: Clear-cell Renal Carcinoma|Clear-cell Metastatic Renal Cell Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study in Adults With Untreated Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: prednisone|DRUG: doxorubicin|DRUG: vincristine|DRUG: methotrexate|DRUG: asparaginase|DRUG: dexamethasone|RADIATION: cranial radiation|DRUG: leucovorin|DRUG: cytarabine|DRUG: hydrocortisone|DRUG: 6-mercaptopurine (6-MP)|DRUG: e. coli L-asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Intensity Aerobic Training in Sub-acute and Chronic Stroke Patients - the Influence on Brain Derived Neurotrophic Factor (BDNF) and Upper-limb Rehabilitation. A Protocol for a Randomized Control Trial and Health Economic Evaluation
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Aerobic Training & UL Motor Training|BEHAVIORAL: Non-aerobic training & UL Motor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK1349572 Drug Interaction Study With Protease Inhibitors
Status: COMPLETED
Conditions: Healthy Subjects|Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK1349572|DRUG: GSK1349572
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: SWOG-9451, Combination Chemo & RT For Patients With Stage III/Stage IV Cancer of the Hypopharynx or Tongue
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Induction chemotherapy|DRUG: cisplatin|DRUG: fluorouracil|RADIATION: low-LET cobalt-60 gamma ray therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scotoma Reduction in AMD Patients Treated With Ranibizumab
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: intravitreal injection Lucentis (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Nodule|Ablation
Interventions: DRUG: Hydromorphone Hydrochloride|DRUG: Morphine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treating the Fear of Gaining Weight in Anorexia Nervosa
Status: TERMINATED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Cognitive-behavioral therapy plus VR-based body exposure|BEHAVIORAL: Cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bandage Contact Lens and Oral Analgesics Versus Patching and Oral Analgesics for Pain Following Pterygium Surgery
Status: UNKNOWN
Conditions: Pterygium
Interventions: PROCEDURE: Patch or bandage contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C|Hemodialysis|Nosocomial Infection
Interventions: DRUG: Elbasvir 50 MG / Grazoprevir 100 MG [Zepatier]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of N-acetylcysteine Versus Placebo as Prophylaxis of Sinusoidal Obstruction Syndrome in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Sinusoidal Obstruction Syndrome (SOS)|Hematopoietic Stem Cell Transplant (HSCT)
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevena™ Incision Management System vs Conventional Management for Wound Healing
Status: UNKNOWN
Conditions: Wound Healing|Prevena|Dirty Abdominal Surgery|Contaminated Abdominal Surgery|Emergency Abdominal Surgery|Negative-Pressure Wound Therapy
Interventions: DEVICE: incisional negative pressure wound therapy|DEVICE: conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: INC280|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of FODMAP Restriction on Persistent GI-symptoms in Coeliac Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Celiac Disease|Irritable Bowel Syndrome|Diet Modification|Gluten Sensitivity
Interventions: OTHER: Low FODMAP diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excessive Crying in Children With Cerebral Palsy and Communication Deficits
Status: COMPLETED
Conditions: Cerebral Palsy|Excessive Crying|Pain
Interventions: OTHER: Placebo|DRUG: Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carvedilol Post-intervention Long-term Administration in Large-scale Trial
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Carvedilol|DRUG: No Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine + Mindfulness for Depression
Status: COMPLETED
Conditions: Depression, Unipolar
Interventions: DRUG: Intravenous Ketamine|BEHAVIORAL: Brief Mindfulness Exercises|BEHAVIORAL: Academic Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis
Status: UNKNOWN
Conditions: Spinal Stenosis
Interventions: BIOLOGICAL: i-FACTOR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Varenicline on Reactivity to Smoking and Drinking Cues
Status: COMPLETED
Conditions: Tobacco Dependence|Alcohol Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment After Irinotecan-based Frontline Therapy: Maintenance With Erbitux (in Patients wtRAS mCRC)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: FOLFIRI and cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of a New Implant System for Bone Conduction Hearing
Status: COMPLETED
Conditions: Deafness; Sensoneural Single Sided|Conductive Hearing Loss|Mixed Hearing Loss
Interventions: DEVICE: Osia System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Just TRAC It! Transitioning Responsibly to Adult Care Using Smart Phone Technology
Status: COMPLETED
Conditions: Congenital Heart Disease|Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: BEHAVIORAL: Teaching session|BEHAVIORAL: Just TRAC It!|BEHAVIORAL: MyHealth Passport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunization Delivery in Obstetrics and Gynecology Settings
Status: COMPLETED
Conditions: Immunization Status Among Obstetrics and Gynecology Patients
Interventions: BEHAVIORAL: Multimodal Vaccine Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Probiotic LGG for Prevention of Side Effects in Patients Undergoing Chemoradiation for Gastrointestinal Cancer
Status: TERMINATED
Conditions: Gastrointestinal Neoplasms
Interventions: DRUG: LGG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus for Thrombocytopenia in SS
Status: NOT_YET_RECRUITING
Conditions: Sjogren Syndrome With Other Organ Involvement
Interventions: DRUG: Hydroxychloroquine|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Utilization of Yoga as a Therapeutic Tool to Promote Physical Activity Behavior Change and Improved Postural Control in Individuals With Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Yoga|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Buprenorphine/Naloxone Film Strips
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: DRUG: Buprenorphine/naloxone Film Strip|DRUG: Buprenorphine/naloxone Film Strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different Settings
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: HFCWC with higher pressure/variable-frequency settings|DEVICE: HFCWC with lower pressure/mid-frequency settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Performance of a Modified Daily Disposable Contact Lens
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Delefilcon A contact lenses with UV Absorber|DEVICE: Delefilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: BAY1436032
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erbitux in Combination With Xeloda and Cisplatin in Advanced Esophago-gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Cetuximab|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Effects of Maitland Mobilization With Mckenzie Exercises on Kinesiophobia and Range of Motion in Upper Cross Syndrome
Status: RECRUITING
Conditions: Upper Cross Syndrome
Interventions: PROCEDURE: McKenzie Exercises|PROCEDURE: Maitland mobilization|PROCEDURE: Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
Status: TERMINATED
Conditions: Beta Thalassemia Major|Beta Thalassemia Intermedia
Interventions: DRUG: SOTATERCEPT (ACE-011)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas
Status: COMPLETED
Conditions: T-Cell Peripheral Lymphoma|Gamma Delta Hepatosplenic T-Cell Lymphoma|Subcutaneous Panniculitis-Like T-Cell Lymphoma|NK T-Cell Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: Etoposide|BIOLOGICAL: Siplizumab|DRUG: Prednisone|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Immune Check-point Inhibitor Following Post-operative Chemo-radiation in Subjects With HPV-negative HNSCC
Status: WITHDRAWN
Conditions: Squamous Cell Head and Neck Carcinoma
Interventions: DRUG: Durvalumab|RADIATION: radiotherapy|DRUG: Placebo|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Study
Status: RECRUITING
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant
Interventions: RADIATION: Hypofractionated Radiation Therapy|OTHER: Questionnaire Administration|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography and Computed Tomography Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Occlusal Reduction on Relief of Pain and Sensitivity to Percussion in Patients With Irreversible Pulpitis
Status: COMPLETED
Conditions: Post Operative Pain|Post-Op Complication
Interventions: PROCEDURE: Occlusal reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 4-HPR and FTI in Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Fenretinide (4-HPR)|DRUG: SCH66336
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Oral Bioavailability of JNJ-63623872 Administered as Oral Concept Formulations Compared to the Current Tablet Formulation
Status: COMPLETED
Conditions: Influenza A Virus
Interventions: DRUG: JNJ-63623872 300 milligram (mg)|DRUG: JNJ-63623872 600 mg|DRUG: JNJ-63623872 600 mg|DRUG: JNJ-63623872 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Wockhardt's Glucose Clamp Study-Human Isophane Susp 30IU/ml/70IU/ml With Novolin70/30, in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: 30% Regular Insulin Human Neutral and 70%Isophane Insulin|BIOLOGICAL: Novolin 70/30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Therapy for Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: DOXIL|DRUG: Withaferin A|DRUG: Ashwagandha|DRUG: Combination of ASWD and DOXIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
Status: RECRUITING
Conditions: Pain|Discomfort|Caregiver|Temporomandibular Disorder|Spine
Interventions: OTHER: Correlation research
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Netarsudil ophthalmic solution 0.02%|DRUG: Ripasudil hydrochloride hydrate ophthalmic solution 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial.
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: Abbreviated MRI of the liver/abdomen|RADIATION: Combined single venous and 3 min equilibrium phase CT of the abdomen/liver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Renal Stone|Nephrolithiasis|Analgesia|Anesthesia
Interventions: PROCEDURE: Erector Spinae Plain Block|PROCEDURE: Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
Status: RECRUITING
Conditions: Premature Infant|Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)|Development, Child|Parent-Child Relations
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Pulsatile Intravenous Insulin Therapy on Cardiac Disease in Patients With Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, With Complications
Interventions: PROCEDURE: Intravenous Insulin on cardiac disease in diabetic pts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PG102P for Uremic Pruritus in HD Patients
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: PG102P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Internal Iliac Artery Ligation Before Cesarean Hysterectomy
Status: UNKNOWN
Conditions: Placenta Accreta
Interventions: PROCEDURE: Cesarean hystrectomy|PROCEDURE: Internal iliac artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Diabetes in Those at Risk by Having a Facilitator and Family Doctor Encourage Healthy Activity and Eating Habits
Status: COMPLETED
Conditions: Prediabetes
Interventions: BEHAVIORAL: Lifestyle changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Japan-Combined Treatment With Olmesartan and a Calcium Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study (J-CORE)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Olmesartan medoxomil ＋Azelnidipine|DRUG: Olmesartan medoxomil + Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I / II Trial of Nintedanib in Asian Hepatocellular Carcinoma Patients
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Sorafenib|DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: Placebo|DRUG: Brivaracetam|DRUG: Brivaracetam|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Status: RECRUITING
Conditions: Healthy Volunteer|Major Depressive Disorder|Depression
Interventions: DRUG: Ketamine|OTHER: Placebo|DEVICE: Cobot TS MV robotic arm for TMS|DEVICE: NeurOptics PLRTM-30000 Pupillometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ziftomenib Maintenance Post Allo-HCT
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia in Remission|NPM1 Mutation|KMT2A Rearrangement
Interventions: DRUG: Ziftomenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CYH33 in Combination With Olaparib an Oral PARP Inhibitor in Patients With Advanced Solid Tumors.
Status: TERMINATED
Conditions: Ovarian Cancer|Breast Cancer|Solid Tumor|Prostate Cancer|Endometrial Cancer
Interventions: DRUG: CYH33
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iNod™ Ultrasound-Guided Needle Biopsy System Study
Status: WITHDRAWN
Conditions: Solitary Pulmonary Nodule|Multiple Pulmonary Nodules|Biopsy, Fine-Needle
Interventions: DEVICE: iNod™ System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of the Safety, Tolerability, and Effectiveness of Halo
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Halo Oral Spray|DRUG: Halo Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label, Long-Term Safety Phase to Evaluate the Efficacy and Safety of TV-44749 in Adults With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: TV-44749 - Dose level 1|DRUG: TV-44749 - Dose level 2|DRUG: TV-44749 - Dose level 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dostarlimab and Cobolimab in Advanced Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer|Advanced Cervical Carcinoma|Metastatic Cervical Cancer|Metastatic Cervical Carcinoma|Recurrent Cervical Carcinoma
Interventions: DRUG: Dostarlimab|DRUG: Cobolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor
Status: RECRUITING
Conditions: Cervical Cancer|Head and Neck Squamous Cell Carcinoma|Oropharyngeal Cancer|Vagina Tumor|Carcinoma of Penis|Anal Carcinoma|Carcinoma of Vulva
Interventions: DRUG: Fludarabine + Cyclophosphamide|BIOLOGICAL: HRYZ-T101 TCR-T Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MGD009 in B7-H3-expressing Tumors
Status: TERMINATED
Conditions: Mesothelioma|Bladder Cancer|Melanoma|Squamous Cell Carcinoma of the Head and Neck|Non Small Cell Lung Cancer|Clear Cell Renal Cell Carcinoma|Ovarian Cancer|Thyroid Cancer|Breast Cancer|Pancreatic Cancer|Prostate Cancer|Colon Cancer|Soft Tissue Sarcoma
Interventions: BIOLOGICAL: MGD009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage
Status: UNKNOWN
Conditions: Uveitis, Anterior|Adalimumab
Interventions: DRUG: Adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: ESK-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cross-Linked Polyelectrolyte (CLP) With Placebo in Heart Failure Subjects
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: CLP|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine
Status: COMPLETED
Conditions: Virus Diseases
Interventions: BIOLOGICAL: Encepur Adults
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Weissella Cibaria JW15 Consumption and NK Cell Activity
Status: COMPLETED
Conditions: Immune Function
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Growth Factor Concentration to Predict an Ankylosing Spondylitis Patient's Response to Infliximab (Study P04041)(COMPLETED)
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma
Status: RECRUITING
Conditions: Lymphoma, B-Cell
Interventions: DRUG: CC-220|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: CC-99282|DRUG: Polatuzumab vedotin|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Tai Chi Chuan （dose 1）|BEHAVIORAL: Tai Chi Chuan （dose 2）|BEHAVIORAL: Tai Chi Chuan （dose 3）|BEHAVIORAL: Tai Chi Chuan （dose 4）|BEHAVIORAL: Tai Chi Chuan （dose 5）|BEHAVIORAL: Tai Chi Chuan （dose 6）|BEHAVIORAL: Tai Chi Chuan （dose 7）|BEHAVIORAL: Tai Chi Chuan （dose 8）|BEHAVIORAL: Tai Chi Chuan （dose 9）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Octreotide Microsphere Formulations in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: The test octreotide microsphere|DRUG: The reference octreotide microsphere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Doses of Hipnos in the Treatment of Adults With Insomnia
Status: WITHDRAWN
Conditions: Insomnia
Interventions: DRUG: Hipnos 3|DRUG: Hipnos 5|OTHER: Hipnos 5 Placebo|OTHER: Hipnos 3 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intubation With Direct Laryngoscopy or Videolaryngoscopy in an Hemoptysis Simulated Situation on Human Cadaver Embalmed With Thiel's Method
Status: COMPLETED
Conditions: Laryngoscope|Hemoptysis|Simulation|Cadaver|Intubation; Difficult or Failed
Interventions: OTHER: direct laryngoscopy|OTHER: videolaryngoscopy McGrath|OTHER: videolaryngoscopy McGrath with suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of Autologous Skin Cell Treating for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: autologous skin cell|PROCEDURE: skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Peripheral Nerve Stimulation of Gluteus Nerves to Improve Hip Strength and Power
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Chronic Knee Pain
Interventions: OTHER: TENS|OTHER: Percutaneous Peripheral Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses
Status: COMPLETED
Conditions: Abscess, Intra-Abdominal
Interventions: DRUG: Moxifloxacin/Metronidazole or Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium for Out-of-Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Heart Arrest, Out-Of-Hospital
Interventions: DRUG: Calcium Chloride|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Teriflunomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution of Balance and Vestibular Function in Patients Treated With Gammaknife Radiosurgery for Vestibular Schwannoma
Status: RECRUITING
Conditions: Vestibular Schwannoma
Interventions: RADIATION: gammaknife radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Comparative Study of Full-Endoscopic Cervical Posterior Discectomy and Anterior Cervical Decompression and Fusion
Status: RECRUITING
Conditions: M-JOA Score
Interventions: PROCEDURE: Percutaneous Posterior Endoscopic Cervical Discectomy|PROCEDURE: Anterior cervical decompression and fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wearable Enhanced Fitness Tracking for Metastatic Breast Cancer Patients Using Endocrine Treatment and Palbociclib
Status: RECRUITING
Conditions: Breast Neoplasm Female|Quality of Life
Interventions: DEVICE: Use of the WeCancer app combined with the smartwatch.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of the Rapid Normalization of Chronic Hyperglycemia and the Practice of Moderate Physical Activity on the "Receptor Activator of Nuclear Factor-kappa B Ligand / Osteoprotégérine (RANKL / OPG) System in Patients Living With Type II Diabetes
Status: COMPLETED
Conditions: Type II Diabetes
Interventions: OTHER: pratice physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Procedural Times Using Colpassist for Robotic-Assisted Sacrocolpopexy; a Randomized Controlled Trial
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Traditional vaginal positioning device|PROCEDURE: Colpassist vaginal positioning device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Urinary Retention and Urinary Track Infection (UTI) After Laparoscopic Assisted Vaginal Hysterectomy (LAVH) for Benign Disease
Status: COMPLETED
Conditions: Hysterectomy|Urinary Retention|Urinary Tract Infection
Interventions: PROCEDURE: on Foley time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients
Status: NOT_YET_RECRUITING
Conditions: Orthostatic Hypotension
Interventions: BEHAVIORAL: Comprehensive rehabilitation training|BEHAVIORAL: Rise-bed Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic, Lactobacillus FARCIMINIS, in Diarrhea Predominant IBS Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Lactobacillus FARCIMINIS|DIETARY_SUPPLEMENT: placebo (starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of The Analgesia Obtained By Infiltration For The Joinings Of Episiotomies (Liropep)
Status: COMPLETED
Conditions: Parturients|Childbirth
Interventions: DRUG: Lidocaïne|DRUG: Ropivacaïne|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Combination therapy with acetazolamide and low-dose loop diuretics|DRUG: High-dose loop diuretics|DRUG: Upfront therapy with oral spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of MetAP2 Inhibition on Bioenergetics and Aging-associated Characteristics in Adipose Tissue in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: PROCEDURE: Abdominal subcutaneous adipose tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Methylenblue-Amodiaquine (MB-AQ)|DRUG: Methylenblue-Artesunate (MB-AS)|DRUG: Artesunate-Amodiaquine (AS-AQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Positron Emission Tomography Study to Measure Cholesterol 24S-Hydroxylase Target Occupancy of TAK-935
Status: COMPLETED
Conditions: Epilepsy, Molecular Mechanisms of Pharmalogical Action, Protective Agents
Interventions: DRUG: TAK-935|DRUG: [18F]MNI-792 (tracer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Knee Arthritis
Interventions: BIOLOGICAL: TTAX03|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effectiveness of a Program Developed to Improve Eye Care for Veterans With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy
Interventions: BEHAVIORAL: Implementation of Proactive Diabetes Eye Care Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Injectable Platelet Rich Fibrin Post Tonsillectomy
Status: NOT_YET_RECRUITING
Conditions: IPRF Post Tonsillectomy
Interventions: OTHER: Use of injectable platelet rich fibrin after tonsillectomy by injection of IPRF in one tonsillar bed and use of other side as control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Bioequivalence Study of (Cytarabine: Daunorubicin) Liposome for Injection
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: (cytarabine: daunorubicin) liposome for injection|DRUG: Vyxeos|DRUG: (cytarabine: daunorubicin) liposome for injection|DRUG: Vyxeos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine Protects Pulpal Stem Cells in Endodontic Revascularization
Status: UNKNOWN
Conditions: Endodontic Disease
Interventions: DRUG: N acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot Study
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lisinopril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buddy Taping Compared to Splint Immobilization for Displaced Paediatric Finger Fractures
Status: COMPLETED
Conditions: Fracture Finger
Interventions: PROCEDURE: fracture immobilization after reduction of displaced finger fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Effects of Statins and Berberine on the Hyperlipemia
Status: TERMINATED
Conditions: Dyslipidemias
Interventions: DRUG: Berberine;Atorvastatin or Rosuvastatin|DRUG: Atorvastatin or Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility|Polyp Uterus|Myoma;Uterus|Adhesion|Hysteroscopy|Uterine Septum|Retained Products of Conception
Interventions: DEVICE: Hyalobarrier® gel endo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Cetoleic Acid on Atherosclerosis (Ketolinsyre's Effekt på Aterosklerose)
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Cetoleic acid|DIETARY_SUPPLEMENT: Control oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mindfulness Based Relapse Prevention: Efficacy and Mechanisms
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention|BEHAVIORAL: Relapse Prevention|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT