pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Feasibility Study to Determine Whether the Botanical Garden Become a Region of Forest Therapy for Cancer Survivors
Status: COMPLETED
Conditions: Neoplasms|Cancer|Mental Health Disorder|Depression
Interventions: BEHAVIORAL: Forest Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Annual Study to Investigate Inactivated Subunit Influenza Vaccine for the 2006/2007 Influenza Season in Europe.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Influvac® subunit influenza vaccine for i.m./deep s.c.injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of ESWT Applied After Botulinum Toxin Injection on Ankle Spasticity in Stroke Patients.
Status: ENROLLING_BY_INVITATION
Conditions: Stroke|Spasticity as Sequela of Stroke
Interventions: DEVICE: Radial Extracorporeal Shock Wave Therapy ONCE|DEVICE: Radial Extracorporeal Shock Wave Therapy TWİCE|DEVICE: Radial Extracorporeal Shock Wave Therapy SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Upadacitinib|DRUG: Placebo for Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Neoadjuvant Chemotherapy for Locally Advanced EGJ Adenocarcinoma
Status: UNKNOWN
Conditions: Adenocarcinoma of Esophagogastric Junction|Neoadjuvant Chemotherapy|Pembrolizumab
Interventions: DRUG: Pembrolizumab Injection [Keytruda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Oxygen Therapy (Optiflow™) in High-risk Cardiac Surgical Patients
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DEVICE: High flow nasal oxygen therapy (Optiflow™)|DEVICE: Standard oxygen therapy (Hudson Type face mask or nasal prongs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Adjunctive Aripiprazole in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Antidepressant + Placebo|DRUG: Antidepressant + Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Interventions: PROCEDURE: the pregnancy rate at IVF / ICSI cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of L-Citrulline Malate on Ankle Brachial Index Among Patients With Coronary Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: L-Citrulline malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Immunological Effect of Vitamin A and Zinc in a Placebo Controlled 4 Cell Trial
Status: COMPLETED
Conditions: Immunity|Diarrhea|Respiratory Tract Infections
Interventions: DRUG: Zinc, or Vitamin A or both
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Vegetable Intake Effect on Heterocyclic Amine Metabolism
Status: TERMINATED
Conditions: Colon Cancer
Interventions: OTHER: grilled hamburger (7 oz) with no vegetables|OTHER: grilled hamburger (7 oz) with steamed broccoli and Brussels sprouts (3g/kg body weight combined)|OTHER: grilled hamburger (7 oz) with steamed parsnips, fresh parsley, and celery sticks (3g/kg body weight combined)|OTHER: grilled hamburger (7 oz) with steamed broccoli, Brussels sprouts, and parsnips plus fresh parsley and celery sticks (6g/kg body weight combined).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 in Type 1 or Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: biphasic human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ampion for the Treatment of Pain and Function in Patients With Severe Osteoarthritis of the Knee.
Status: TERMINATED
Conditions: Severe Osteoarthritis of the Knee
Interventions: BIOLOGICAL: Ampion|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of ABI-007 in Patients With Advanced Non-Hematologic Malignancies
Status: COMPLETED
Conditions: Neoplasms|Metastases, Neoplasm
Interventions: DRUG: ABI-007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Drink on Number of Salivary Mutans Streptococci in School Going Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: probiotic drink|DIETARY_SUPPLEMENT: Placebo Comparator: plain, unsweetend, unflavored pasturised milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Virtual Reality on Peri-interventional Pain, Anxiety and Distress in a Pediatric Oncology Outpatient Clinic
Status: COMPLETED
Conditions: Pediatric Cancer|Procedural Anxiety|Procedural Pain
Interventions: DEVICE: Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: primary PCI|DRUG: enoxaparin|PROCEDURE: catheterisation|DRUG: tenecteplase|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|End Stage Renal Disease
Interventions: DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Performance of Princess® FILLER for the Treatment of Facial Lipoatrophy, Asymmetry or Scars
Status: COMPLETED
Conditions: Facial Lipoatrophy|Morphological Asymmetry of the Face|Debilitating Scars
Interventions: DEVICE: Princess® FILLER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interpersonal Psychotherapy for Depression in People With Heart Failure
Status: COMPLETED
Conditions: Depression|Heart Failure, Congestive
Interventions: BEHAVIORAL: Interpersonal and behavioral psychotherapy|BEHAVIORAL: Attention control (AC) condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Performance of a Categorical Loudness Scaling Based Fitting With a Behavioural Fitting in Adults With a Nucleus Cochlear Implant 3 Months Post-activation
Status: RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: Categorical loudness scaling based fitting using the Nexus Research System.|DEVICE: Behavioural fitting using Custom Sound Suite (CSS 6.3) Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence
Status: TERMINATED
Conditions: Nicotine Dependence
Interventions: DRUG: Selegiline + nicotine replacement therapy|DRUG: placebo + nicotine replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video-assisted Anal Fistula Treatment (VAAFT) Versus Fistula-tract Laser Closure (Filac) Versus Conventional Seton in the Management of Anal Fistula
Status: UNKNOWN
Conditions: Video Assisted Anal Fistula Treatment
Interventions: PROCEDURE: Video-assisted anal fistula treatment (VAAFT) versus Fistula-tract Laser Closure (filac) versus Conventional seton in the Management of anal fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Based Liver Fat Quantification (LFQ) Pilot Study
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis
Interventions: DEVICE: Investigational Liver Fat Quantification Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SuPRA: Using Wearable Activity Trackers With a New Application to Improve Physical Activity in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Joint Diseases|Knee Osteoarthritis
Interventions: BEHAVIORAL: Education session, Fitbit/FitViz, PT counselling|BEHAVIORAL: Same intervention with a 3 month delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation
Status: COMPLETED
Conditions: Bowel Preparation|Sodium Picosulfate and Magnesium Citrate|Polyethylene Glycol With Ascorbic Acid
Interventions: DRUG: sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1)
Status: UNKNOWN
Conditions: Arterial Occlusive Disease|Ischemia|Ulcers|Peripheral Vascular Disease
Interventions: GENETIC: NL003|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLYCOSA Study:Effect of PAP Treatment on Glycemic Control in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DEVICE: Positive Airway Pressure therapy|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide for Structural p53 Mutations
Status: UNKNOWN
Conditions: Arsenic Trioxide|p53 Mutations|Refractory Cancer|Intractable Cancer
Interventions: DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Treatment for Obesity Among Underserved Populations
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Single Text Messaging (TM1)|BEHAVIORAL: Patient Navigation (PN)|BEHAVIORAL: Multiple Text Messaging (TM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CP-675,206 in Combination With Short Term Androgen Deprivation in Patients With Stage D0 Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Bicalutamide and CP-675,206 (Tremelimumab)|DRUG: Bicalutamide, CP-675,206 (tremelimumab)|DRUG: Bicalutamide, CP-675,206 (Tremelimumab)|DRUG: Bicalutamide, CP-675,206 (Tremelimumab)|DRUG: Bicalutamide, CP-675,206
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Caesarian Section
Status: COMPLETED
Conditions: Pain, Postoperative|Pruritus|Nausea and Vomiting Following Administration of Anaesthetic Agent|Consumption
Interventions: DRUG: Bupivacaine-fentanyl-morphine elective group|DRUG: Bupivacaine-fentanyl elective group|DRUG: Bupivacaine-fentanyl emergency group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft
Status: UNKNOWN
Conditions: Badly Broken Maxillary Premolars Indicated for Extraction
Interventions: DEVICE: immediate premolar implant with xenograft and allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence Among HIV+ Rwandan Youth: A TI-CBTe Indigenous Leader Model
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Trauma-Informed Cognitive Behavioral Therapy enhanced (TI-CBTe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals
Status: UNKNOWN
Conditions: Asplenia|β-thalassemia Major
Interventions: BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Effect of Motor Cortex Stimulation in Patients Suffering From Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Pain, Intractable|Central Pain Syndrome|Facial Pain
Interventions: DEVICE: Specify, model 3998, Medtronic Inc., Minneapolis, MN, USA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 Trial
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone in Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied 4 Times Daily in Subjects With Acute Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: Diclofenac sodium topical gel 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Congenital Heart Disease Physical Activity Lifestyle Study V.2
Status: RECRUITING
Conditions: Heart Defects, Congenital|Cardiovascular Disease Other
Interventions: BEHAVIORAL: Physical Activity Monitoring|BEHAVIORAL: Tailored Exercise Prescription|BEHAVIORAL: Healthy Lifestyle Education|BEHAVIORAL: Physical Activity Lifestyle Intervention Informed by the Theory of Planned Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glycosylated Hemoglobin and Risk of Perioperative Major Cardiovascular Events in Diabetic Patients Undergoing Coronary Bypass Revascularization (HbA1c)
Status: COMPLETED
Conditions: Cardiovascular Event|Coronary Artery Bypass Graft|Diabetes Mellitus
Interventions: PROCEDURE: Coronary Bypass Revascularization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome
Status: COMPLETED
Conditions: Premature Birth of Newborn|Enterocolitis, Necrotizing
Interventions: DRUG: Ampicillin|DRUG: Gentamicins|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
Status: UNKNOWN
Conditions: Forearm Injuries|Pain, Acute|Pediatric ALL
Interventions: DRUG: Oxycodone|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed Appropriate
Status: COMPLETED
Conditions: Advanced Breast Cancer Female
Interventions: DRUG: Palbociclib|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Performance of the SeptiCyte LAB Test for Antibiotic Stewardship in Mesenteric Ischemia
Status: NOT_YET_RECRUITING
Conditions: Acute Mesenteric Ischemia|Sepsis Bacterial|Intra-abdominal Infection
Interventions: DEVICE: Septicyte Lab Test pre operative|DEVICE: Septicyte Lab Test post operative
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Continuous Positive Airway Pressure Treatment on Inflammation in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Inflammation|Continuous Positive Airway Pressure
Interventions: DEVICE: CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccine (Vero Cells) in Healthy Population Aged 18 Years and Above(COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: medium dosage inactivated SARS-CoV-2 vaccine|BIOLOGICAL: high dosage inactivated SARS-CoV-2 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation
Status: COMPLETED
Conditions: Immune System and Related Disorders
Interventions: DRUG: Ibuprofen|BEHAVIORAL: Compound Exercise of Push-ups|DRUG: oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study for Patients With Chronic HCV (GT 1 or 3) Who Relapsed to Previous (Peg)Interferon/ Ribavirin Combination Therapy
Status: UNKNOWN
Conditions: Hepatitis C, Chronic|Relapse
Interventions: DRUG: Peginterferon alfa-2a, Ribavirin, Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies
Status: RECRUITING
Conditions: Cystic Fibrosis|CFTR Gene Mutation
Interventions: PROCEDURE: Nasal cells sampling|PROCEDURE: Rectal biopsy sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Gentamicin and Vancomycin for Vascular Surgical Site Infection Prophylaxis
Status: UNKNOWN
Conditions: Vascular Diseases|Peripheral Vascular Disease|Surgical Site Infection|Bypass Complication
Interventions: DRUG: Topical vancomycin paste (1g vancomycin powder + 4mL sterile saline) and Collatamp G gentamicin-eluting sponge (Azralez Pharmaceuticals; 2.0mg gentamicin sulphate/cm2 to cover wound)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Umbilical Mesenchymal Stem Cells for Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: mesenchymal stem cells|BIOLOGICAL: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 30% Supramolecular Salicylic Acid Combined With Supramolecular Active Zinc in the Treatment of Malassezia Folliculitis
Status: COMPLETED
Conditions: Malassezia Folliculitis
Interventions: DRUG: 30% supramolecular salicylic acid|DRUG: supramolecular active zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors Harboring NTRK Fusion|Primary Central Nervous System Tumors Harboring NTRK Fusion
Interventions: DRUG: ICP-723
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: PEG-ELS|DRUG: BLI800
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate Alzheimer's Dementia (Syndrome of Deficiency of Spleen and Kidney)
Status: NOT_YET_RECRUITING
Conditions: Alzheimer's Dementia
Interventions: DRUG: Wujia Yizhi granules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Interventions in Asthma Treatment: Sprouts Study
Status: TERMINATED
Conditions: Asthma|Allergy
Interventions: OTHER: Broccoli Sprouts|OTHER: Alfalfa Sprouts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Doses of Rozibafusp Alfa (AMG 570) in Adults With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rozibafusp Alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring Platforms and Chemotherapy-Associated Toxicity
Status: RECRUITING
Conditions: Cancer|Chemotherapeutic Agent Toxicity
Interventions: DEVICE: Contigo Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pemigatinib in Participants With Solid Tumors With FGFR Mutations or Translocations (FIGHT-208)
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors|FGFR Mutations|FGFR Translocations
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GXT - GeneXpert or Chest-X-ray or Tuberculin Skin Testing for Household Contact Assessment
Status: COMPLETED
Conditions: Latent Tuberculosis
Interventions: OTHER: Strategy 2: Symptom screen, Genexpert and TST|OTHER: Strategy 3:Symptom screen, CXR but NO TST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Medication Adherence Through SMS (Short Messaging Service) in Adult Stroke Patients: a Randomised Controlled Behaviour Intervention Trial
Status: COMPLETED
Conditions: Medication Adherence|Stroke
Interventions: BEHAVIORAL: SMS- Short Messaging Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery
Status: COMPLETED
Conditions: Cervical Compression Myelopathy|Ischemia|Reperfusion Injury|Spinal Cord Injury
Interventions: PROCEDURE: limb remote ischemic preconditioning (LRIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Romiplostim to Treat Low Platelet Counts Following Chemotherapy and Autologous Hematopoietic Cell Transplantation in People With Blood Cancer
Status: COMPLETED
Conditions: Multiple Myeloma|Hodgkin Lymphoma|Non-Hodgkin Lymphoma|HDT-AHCT
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superiorly Based Pharyngeal Flap Versus Myomucosal Resection and Direct Closure
Status: COMPLETED
Conditions: Velopharyngeal Insufficiency
Interventions: PROCEDURE: myomucosal resection and direct closure|PROCEDURE: superiorly based flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions
Status: COMPLETED
Conditions: Neurodegenerative Diseases|Osteoarthritis|Erectile Dysfunction|Autoimmune Diseases|Cardiomyopathies|Emphysema
Interventions: PROCEDURE: Administration of autologous adipose derived SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Single-Masked, Long-Term, Safety and Tolerability Study of VEGF Trap-Eye in AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: VEGF Trap Eye
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Self-Management Support in Diabetes Through Patient Engagement
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Enhanced Engagement Protocol for CTH (EE-CTH)|BEHAVIORAL: Connection to Health (CTH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: BMS-986249|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Weekly Erythropoietin Dosing in Preterm Infants
Status: COMPLETED
Conditions: Preterm Infants
Interventions: DRUG: three times weekly Epo|DRUG: weekly Epo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Status: RECRUITING
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: PULPOTOMY OF MATURE PERMENANT TEETH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB)
Status: COMPLETED
Conditions: Multidrug Resistant Tuberculosis
Interventions: DRUG: Delamanid|DRUG: Delamanid Pediatric Formulation (DPF)|DRUG: Optimized Background Regimen (OBR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Outcome Of Distal Mesogastric Fixation After Laparoscopic Sleeve Gastrectomy;
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: distal mesogastric fixation after sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Congenital Stationary Night Blindness With an Alga Containing High Dose of Beta Carotene
Status: COMPLETED
Conditions: Night Blindness
Interventions: DIETARY_SUPPLEMENT: alga Dunaliella bardawil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Hematologic Malignancy|Malignant Lymphoma
Interventions: DRUG: Romidepsin|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Placebo-controlled, Tourette Syndrome Study.
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: Topiramate (drug)|DRUG: placebo/sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Autonomic Nervous System and Obesity
Status: COMPLETED
Conditions: OBESITY|HYPERTENSION|PURE AUTONOMIC FAILURE|SHY-DRAGER SYNDROME
Interventions: DRUG: Trimethaphan|DRUG: Trimethaphan|DRUG: Pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Elucidating the Necessary Active Components of Training
Status: UNKNOWN
Conditions: Alzheimer Disease|Cognitive Change|Cognitive Impairment
Interventions: BEHAVIORAL: BUD1|BEHAVIORAL: BUD2|BEHAVIORAL: TDD1|BEHAVIORAL: TDD2|BEHAVIORAL: CSA10|BEHAVIORAL: CSA20|BEHAVIORAL: CSA30|BEHAVIORAL: CSA40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Compare the Efficacy of Levocetirizine to Montelukast in Reducing Symptoms of SAR in Sensitive Subjects Exposed to Ragweed Pollen
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ca:Mg Ratio and Cognitive Function
Status: COMPLETED
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Magnesium glycinate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome
Status: COMPLETED
Conditions: Organic Brain Syndrome, Nonpsychotic|Neurocognitive Disorders|Mental Disorder, Organic|Delirium, Dementia, Amnestic, Cognitive Disorders|Nonpsychotic Organic Brain Syndrome|Organic Mental Disorder|Encephalopathy, Post-Traumatic, Chronic|Encephalopathy, Ischemic|Brain Ischemia
Interventions: DRUG: Intranasal auto-M2-BFs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Trauma, Nervous System|Reperfusion Injury|Ischemia, Brain
Interventions: DEVICE: CellAegis Technologies autoRIC device|OTHER: Best Practice Management of Traumatic Brain Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Es-ketamine on Postoperative Delirium Among Old Patients With Lobectomy
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: PROCEDURE: lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation
Status: COMPLETED
Conditions: Heat Stress Disorders
Interventions: DRUG: Daily aspirin (ASA)|OTHER: Active cooling|DRUG: Acute aspirin (ASA)|OTHER: Passive cooling|DRUG: Daily placebo|DRUG: Acute placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of AP026 (TQA2226) for Injection in Adult Subjects.
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: AP026 (TQA2226) for injection|DRUG: AP026 (TQA2226) for injection matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Chemoresistance in Advanced Ovarian Cancer Via Targeting Hypoxia
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Carcinoma|Hypoxia
Interventions: DEVICE: Imaging with 18F-EF5 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Moxaverine and Placebo on Ocular Blood Flow
Status: COMPLETED
Conditions: Regional Blood Flow|Ocular Physiology|Retina
Interventions: DRUG: Moxaverine|DRUG: Moxaverin 150mg|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Luteal Phase Support With Daily Administration of Gonadotropin-releasing Hormone Agonist Compared to Progesterone/Estradiol in IVF/ICSI Cycles With Ovulation Triggering With GnRH-a
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Gonadotropin-releasing hormone agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial
Status: RECRUITING
Conditions: Cirrhosis, Liver
Interventions: OTHER: Evidence-based standardized Cirrhosis order set
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cardiac Output Autonomic Stimulation Therapy for Heart Failure - Hemodynamic Effects
Status: UNKNOWN
Conditions: Heart Failure Acute|Heart Failure
Interventions: DEVICE: NeuroTronik CANS Therapy® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer
Status: COMPLETED
Conditions: COVID-19|Sars-CoV2|Cancer|Solid Tumor|Carcinoma|Blood Cancer
Interventions: DRUG: TL-895
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOW To Optimally Implant BioResorbable Scaffold - Intravascular Imaging Versus Quantitative Coronary Angiography Guidance
Status: TERMINATED
Conditions: Coronary Stenosis
Interventions: DEVICE: quantitative coronary angiography guided Bioresorbable scaffold implantation|DEVICE: imaging guided Bioresorbable scaffold implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser 360iQ: Optimal Light-laser Combination Therapy
Status: COMPLETED
Conditions: Photodamage
Interventions: DEVICE: Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Fibromyalgia Treated With Milnacipran
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Milnacipran|PROCEDURE: Skin biopsy|PROCEDURE: Skin Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine to Prevent COVID-19 Disease Amongst Healthcare Workers
Status: WITHDRAWN
Conditions: Corona Virus Infection
Interventions: DRUG: Apo-Hydroxychloroquine|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Low Concentration Atropine on Pupillary Size and Accommodative Amplitude
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: 0.01% atropine eye drops|DRUG: 0.02% atropine eye drops|DRUG: 0.03% atropine eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: ALXN2050
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Efficacy of Eductyl® for the Treatment of Patients With Dyschesia
Status: COMPLETED
Conditions: Dyschesia
Interventions: DRUG: Eductyl suppository|DRUG: Placebo suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Acute Respiratory Infection in Taiwanese Institutionalized Elderly
Status: WITHDRAWN
Conditions: Acute Respiratory Infection
Interventions: DRUG: BCG Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Almond Consumption on the Human Gastrointestinal Microbiota and Metabolic Health
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Almonds|DIETARY_SUPPLEMENT: Pretzels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Test Different Doses of BI 891065 Alone and in Combination With BI 754091 in Asian Patients With Different Types of Advanced Cancer (Solid Tumours)
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: BI 891065|DRUG: BI 754091
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Toxicity Fludarabine (Flu) + Cyclophosphamide (CPM) + Rabbit Antithymocyte Globulin (rATG) Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia (SAA)
Status: UNKNOWN
Conditions: Aplastic Anemia
Interventions: DRUG: Cyclophosphamide, Fludarabine, Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Autologous Human Schwann Cells (ahSC) in Subjects With Subacute SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Paraplegia
Interventions: BIOLOGICAL: Autologous Human Schwann Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: orteronel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler
Status: COMPLETED
Conditions: Fetal Growth Retardation
Interventions: PROCEDURE: Management based on sFlt-1/PlGF values
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discretionary Food Sources and Stress Perception
Status: WITHDRAWN
Conditions: Stress Perception|Discretionary Calories|Over All Health
Interventions: OTHER: Liquid: Sugar sweetened beverage consumption|OTHER: Solid: Grain based desserts and candy consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor(SPEAC) for Adults With Emotional Distress (Phase 2)
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Lumen Coached PST Intervention.|BEHAVIORAL: Human Coached PST Intervention.|BEHAVIORAL: Optional (delayed) Lumen Coached PST (Waitlist control).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Axicabtagene Ciloleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine phosphate|DRUG: Prednisone|DRUG: Diphenhydramine|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 7T MRI to Evaluate Cartilage Defects in the Knee
Status: COMPLETED
Conditions: Cartilage Injury|Knee Injuries|Arthropathy of Knee|Cartilage Damage|Knee Pain Swelling
Interventions: DIAGNOSTIC_TEST: 7 Tesla Magnetic Resonance Imaging Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addition to Infant Formula of 2-fucosyllactose (2-FL)
Status: COMPLETED
Conditions: Growth of Infants
Interventions: OTHER: sole source nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: tDCS Versus tsDCS for Endometriosis-related Chronic Pelvic Pain Treatment
Status: UNKNOWN
Conditions: Endometriosis|Pelvic Pain|Transcranial Direct Current Stimulation|Spinal Cord Stimulation
Interventions: DEVICE: Transcranial DCS Healthy Volunteers|DEVICE: Transspinal DCS Healthy Volunteers|DEVICE: Transcranial DCS CPP patients|DEVICE: Transspinal DCS CPP patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Promoting Vegetable Intake in Preschool Aged Children
Status: COMPLETED
Conditions: Food Habits|Food Preferences|Behavior|Health Behavior
Interventions: BEHAVIORAL: Taste exposure|BEHAVIORAL: Nutritional education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stromal Vascular Fraction (SVF) for Knee Post-Trauma Osteoarthritis (PTOA)
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis
Interventions: GENETIC: Adipose Derived (AD) Stromal Vascular Fraction (SVF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Whether Disease-free Intervals Can Guide Endocrine Combined Targeted Therapy for ER+/HER2+ Advanced Breast Cancer (T-sunflower)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: pyrotinib|DRUG: Dalpiciclib|DRUG: fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT