pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Diabetes In Relation to Hospitalized COVID-19 Patents At Assiut University Hospital
Status: UNKNOWN
Conditions: Diabetes Mellitus|COVID-19
Interventions: DIAGNOSTIC_TEST: Reverse transcription polymerase chain reaction (RT-PCR)|DIAGNOSTIC_TEST: Glycated haemoglobin (HbA1C)|RADIATION: High Resolution Computed Tomography (HRCT)|DIAGNOSTIC_TEST: Routine Laboratory investigations|DIAGNOSTIC_TEST: Random Blood Sugar (RBS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Cervical Cancer|Endometrial Cancer|Esophageal Cancer|Fallopian Tube Cancer|Gastric Cancer|Ovarian Cancer|Sarcoma|Vaginal Cancer|Vulvar Cancer
Interventions: OTHER: informational intervention|PROCEDURE: assessment of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease)
Status: NOT_YET_RECRUITING
Conditions: Steinert's Disease|Myotonic Dystrophy 1|Metformin
Interventions: DRUG: Treatment taken
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: High Grade B-Cell Non-Hodgkin's Lymphoma|Intermediate Grade B-Cell Non-Hodgkin's Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Anti-CD19-CAR CMV-specific T-lymphocytes|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Leukapheresis|PROCEDURE: Lymphodepletion Therapy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine|PROCEDURE: Positron Emission Tomography|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mulligan and Mckenzie Exercises Alongwith Stabilization Exercises in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: MCKENZIE AND STABILIZATION EXERCISES|PROCEDURE: MULLIGAN AND STABILIZATION EXERCISES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study Aims to Investigate the Effects of Oral Inositols on Insulin-resistance in Children With Obesity.
Status: NOT_YET_RECRUITING
Conditions: Obesity|Prediabetic State|Dyslipidemias|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: INOSITOLS|DIETARY_SUPPLEMENT: CELLULOSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Tolerability of Two New Different Extended Release Capsules of BIBV 308 SE, Versus a Solution of BIBV 308 SE in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBV 308 SE solution|DRUG: BIBV 308 SE capsule L|DRUG: BIBV 308 SE capsule S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Animated Movies and Storybooks on Fear and Anxiety Levels in Children With Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Child, Only|Anxiety|Fear|Nurse
Interventions: OTHER: Animation movie, story book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Happy Homes, Healthy Families: A Relationship Strengthening Intervention for Pregnant Couples Affected by HIV in Zambia
Status: COMPLETED
Conditions: HIV Infections|Pregnancy Related
Interventions: BEHAVIORAL: Couples Counseling|OTHER: Enhanced Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of the Success Rate Of Cannulation Between The Accuvein Apparatus And Standard Technique
Status: COMPLETED
Conditions: Cannulation
Interventions: PROCEDURE: Cannulation using Accuvein device|PROCEDURE: Standard Cannulation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Study of ExAblate Thalamotomy for Treatment of Chronic Trigeminal Neuropathic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Trigeminal Neuropathic Pain
Interventions: DEVICE: Transcranial ExAblate|DEVICE: Sham Transcranial ExAblate|DEVICE: Crossover Transcranial Exablate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Study Between Intramedullary Locking Nails and Locking Plates for Treatment of Proximal Humerus Fractures
Status: COMPLETED
Conditions: Proximal Humerus Fractures
Interventions: PROCEDURE: Intramedullary nail|PROCEDURE: Locked plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome (MDS)
Interventions: DRUG: TQB3455 tablet+Azacitidine for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Monoxide Breath Sensor System Performance, Human Factors, and Usability Assessment Conducted in a Single Visit
Status: COMPLETED
Conditions: Smoking, Tobacco
Interventions: DEVICE: Carbon Monoxide Breath Sensor System (COBSS)|DEVICE: Bedfont - Micro+™ Smokerlyzer®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness Comparison of Skin Micro-grafts vs Meshed Split Thickness Skin Grafts
Status: UNKNOWN
Conditions: Skin Ulcer|Burns
Interventions: PROCEDURE: Skin micro Grafts|PROCEDURE: Standard skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Promote Skin Health
Status: COMPLETED
Conditions: Skin Cancer|Skin Cancer Melanoma|Squamous Cell Carcinoma|Basal Cell Carcinoma
Interventions: BEHAVIORAL: Facial Morphing Intervention|BEHAVIORAL: Mindfulness Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Efficacy of Inhaled Bimosiamose for the Treatment of Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Bimosiamose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors
Status: COMPLETED
Conditions: Speech Sound Disorder
Interventions: BEHAVIORAL: Visual-acoustic biofeedback|BEHAVIORAL: Ultrasound biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vitamin D in the Treatment of OAB-wet in Children
Status: RECRUITING
Conditions: Urinary Bladder, Overactive|Overactive Bladder|Urinary Incontinence, Urge
Interventions: BEHAVIORAL: urotherapy|DRUG: Solifenacin Succinate|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophagus Deviation During Radiofrequency Ablation of Atrial Fibrillation - EASY AF STUDY
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: esolution catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Study to Investigate the Efficacy of Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: GW-1000-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Laughter Therapy on Nursing Students
Status: COMPLETED
Conditions: Mental Stress|Insomnia|Sleep Disorder|Mental Health Disorder
Interventions: BEHAVIORAL: Laughter Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy
Status: RECRUITING
Conditions: Primary Membranous Nephropathy
Interventions: DRUG: SNP-ACTH (1-39) Gel|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Japanese Phase 2 Study to Evaluate the Efficacy and Safety of Pomalidomide in Subjects With Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study to Evaluate and Compare the Rate and Extent of Inflammation After a Single Intravitreal Injection of Ranibizumab vs. a Single Intravitreal Injection of Aflibercept in Treatment Naive and Treatment Experienced Patients.
Status: COMPLETED
Conditions: Neovascular Age Related Macular Degeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aripiprazole in the Treatment of Post-Traumatic Stress Disorder Symptoms
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Aripiprazole|BEHAVIORAL: Interpersonal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer
Status: UNKNOWN
Conditions: Precision Cells|Transcatheter Arterial Chemoembolization|Advanced Liver Cancer
Interventions: PROCEDURE: TACE|BIOLOGICAL: Precision Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Fosinopril Sodium / Hydrochlorothiazide 20/ 12.5 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fosinopril sodium and hydrochlorothiazide 20-12.5 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of R-Pdf/Gbb in Healing Wounds Caused by Third Degree Thermal and Electrical Burns
Status: UNKNOWN
Conditions: Burns|Electric Burns
Interventions: DRUG: R-Pdf/Gbb 0.01% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Mycobacterium Tuberculosis|LTBI (Latent TB Infection)|Malnutrition|Diabetes Mellitus|Helminth Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Idelalisib (GS-1101) in Combination With Rituximab for Previously Treated Indolent Non-Hodgkin Lymphomas
Status: TERMINATED
Conditions: Indolent Non-Hodgkin's Lymphomas
Interventions: DRUG: Placebo|DRUG: Rituximab|DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Combined With Tislelizumab and HAIC in Patients With Advanced Colorectal Liver Metastases Cancer Who Failed Standard Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: HAIC|DRUG: Fruquintinib|DRUG: Tislelizumab|DRUG: Raltitrexed|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Mitral Regurgitation
Interventions: DEVICE: Transmural Systems Transcatheter Mitral Cerclage Annuloplasty (TMCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of BondEase to Treat Traumatic Lacerations and Surgical Incisions
Status: COMPLETED
Conditions: Traumatic Lacerations or Surgical Incisions
Interventions: DEVICE: BondEase|PROCEDURE: CWCD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Contractile Reserve: a Therapeutic Target in Heart Failure With Preserved Ejection Fraction(HFpEF)
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Pulmonary Disease|Left Ventricular Hypertrophy/Hypertension
Interventions: DRUG: Dobutamine|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg vs Placebo as Adjuvant Treatment in Chronic Migraine -
Status: RECRUITING
Conditions: Chronic Migraine, Headache|Overuse Headache Medication
Interventions: DRUG: Placebo oral drops|DRUG: Cannabidiol + Cannabigerol + Tetrahydrocannabinol 133/66/4mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: serum aquaporin 4 antibody (AQP-4-Ab)|DIAGNOSTIC_TEST: serum MOG antibody (anti-MOG)|DIAGNOSTIC_TEST: MRI brain, spine and orbit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study
Status: COMPLETED
Conditions: Substrate Absorption|Substrate Oxidation|Glucose Regulation
Interventions: OTHER: trt 1|OTHER: trt 2|OTHER: trt 3|OTHER: trt 4|OTHER: trt 5|OTHER: trt 6|OTHER: trt 7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma Multiforme|Glioblastoma, IDH-wildtype|Radiotherapy; Complications|Cancer Brain
Interventions: RADIATION: hypofractionated stereotactic radiotherapy|PROCEDURE: Stereotactic biopsy|PROCEDURE: resection|DRUG: Chemotherapy|RADIATION: radiotherapy Stupp protocol|DRUG: Chemotherapy Stupp Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Control of WAG in PACU Within Patient and Caregiver Breathing Zone
Status: COMPLETED
Conditions: Waste Anesthetic Gas (WAG) Emanating From Patients Post-operative Recovery
Interventions: DEVICE: ISO-Gard Mask|DEVICE: Standard oxygen mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Deferred or Immediate Stent Implantation Based on Microvascular Function in STEMI
Status: TERMINATED
Conditions: Microcirculatory Perfusion|ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Deferred or Immediate Stent Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demographical and Clinical Profile of Patients on Dual Antıplatelet Therapy and Mean Precise-DAPT and DAPT Scores in Turkey
Status: COMPLETED
Conditions: Anti-platelet Therapy
Interventions: OTHER: Demographical and Clinical Profile of Patients on Dual Antıplatelet Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension|Coronary Artery Disease|Atrial Fibrillation|Stroke
Interventions: OTHER: PHCVRS Intervention|OTHER: Personal Health Record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CeraShield™ Endotracheal Tube Feasibility Study
Status: UNKNOWN
Conditions: Intubation, Intratracheal
Interventions: DEVICE: CeraShield Endotracheal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Obstructive Sleep Apnea and Glucose Metabolism
Status: SUSPENDED
Conditions: Sleep Apnea|Glucose Metabolism Disorders
Interventions: PROCEDURE: Positive Airway Pressure|PROCEDURE: Supplemental Oxygen|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) B-cell Acute Lymphoblastic Leukemia
Status: NOT_YET_RECRUITING
Conditions: Leukemia
Interventions: BIOLOGICAL: IM19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Improvement of Depression of Fluoxetine Combined With ATP
Status: RECRUITING
Conditions: Depression
Interventions: DRUG: Control group: Fluoxetine and Placebo|DRUG: Experimental group: Fluoxetine and ATP|DRUG: Control group: Fluoxetine and Phosphocreatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders
Status: NOT_YET_RECRUITING
Conditions: Behavioral Variant of Frontotemporal Disorder (bvFTD)|Phenocopy Frontotemporal Dementia (phFTD)|Frontal Variant of Alzheimer Disease|Bipolar Disorder
Interventions: OTHER: Submission of the NEO-PI-3 questionnaire|OTHER: Submission of the Interpersonal Reactivity Index questionnaire (IRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Cognitive Behavioral Therapy-Based Text Message Intervention for Methamphetamine Dependence
Status: UNKNOWN
Conditions: Amphetamine-Related Disorders
Interventions: BEHAVIORAL: CBT- based SMS text messaging intervention|BEHAVIORAL: CBT group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients
Status: RECRUITING
Conditions: Peritoneal Dialysis|Exercise|Gastrointestinal Function|Quality of Life|Chronic Kidney Diseases
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambrosia: Evaluating the Effects of a Food-As-Medicine Platform on Gut Microbiome Composition and Metabolism
Status: RECRUITING
Conditions: Impact of Dietary Chages Directed by Medical Nutrition Therapy on Gut Microbiome Composition
Interventions: BEHAVIORAL: Nutrition Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of a Nature-Based Mindfulness-Compassion Intervention for Older Adults Delivered Using Virtual Reality
Status: COMPLETED
Conditions: Mental Health Wellness 1|Healthy Aging
Interventions: BEHAVIORAL: Virtual Reality (VR) Meditation|BEHAVIORAL: Psychoeducational Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vibrotactile Foot Device for Freezing of Gait in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Freezing of Gait
Interventions: DEVICE: Vibrotactile foot device (Smart shoe)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Emotional and Motivational Development to Support Well-being and Retention in Diverse University Students
Status: UNKNOWN
Conditions: Healthy
Interventions: BEHAVIORAL: Contextualized Wish-Outcome-Obstacle-Plan (WOOP) intervention|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Trifluridine/Tipiracil Combined With Fufuquitinib for Third-line Treatment of mCRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|Drug Therapy
Interventions: DRUG: trifluridine/tipiracil combined with fufuquitinib|DRUG: fufuquitinib|DRUG: Trifluridine/tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method
Status: COMPLETED
Conditions: Vitamin A Deficiency|Malaria|Inflammation
Interventions: OTHER: Retinol Isotope Dilution (RID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
Status: RECRUITING
Conditions: Hidradenitis Suppurativa|Healthy Volunteers
Interventions: DEVICE: Radiofrequency-Based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: LATINO Study: A Study of Mircera for the Maintenance Treatment of Dialysis Patients With Chronic Renal Anemia.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness and Cost-utility of Liberal vs Restrictive Red Blood Cell Transfusion Strategies in Patients With Acute Myocardial Infarction and Anaemia.
Status: COMPLETED
Conditions: Myocardial Infarction|Anemia|Blood Transfusion
Interventions: PROCEDURE: Restrictive transfusion|PROCEDURE: Liberal transfusion|BIOLOGICAL: red blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Comparative Analysis of Bretschneider and St. Thomas Cardioplegia Solution in Case of Mitral Valve Repair Via Anterolateral Right Thoracotomy
Status: COMPLETED
Conditions: Mitral Valve Reconstruction
Interventions: OTHER: cardioplegia with HTK-Bretschneider cardioplegic solution|OTHER: cardioplegia with St. Thomas cardioplegic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick
Status: COMPLETED
Conditions: Pruritus
Interventions: PROCEDURE: 50 µg Histamine|PROCEDURE: 15 µg Histamine|PROCEDURE: 5 µg Histamine|PROCEDURE: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety and Efficacy of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (T2DM) and Inadequate Glycemic Control (MK-3102-011)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Placebo to Omarigliptin|DRUG: Metformin|DRUG: Placebo to metformin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group-based Acceptance and Commitment Therapy for Family Caregivers of People With Dementia in Japan
Status: RECRUITING
Conditions: Dementia|Family Caregivers
Interventions: BEHAVIORAL: Group-based acceptance and commitment therapy (ACT)|BEHAVIORAL: Group-based cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Liver Function
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: GST-HG171 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Ibandronate 150 mg Monthly on Structural Properties of Bone in Postmenopausal Osteoporosis (SPIMOS-3D)
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: ibandronate, calcium and vitamin D|DRUG: placebo,calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Bioavailability and Food Effect of a Single TAK-935 Dose in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-935 Tablets|DRUG: TAK-935 Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Botulinum Toxin for Trigeminal Neuralgia
Status: UNKNOWN
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Botulinum Toxin type A (intradermal / submucosal injection at pain area)|DRUG: Botulinum Toxin type A (intra-masseter injection on the ipsilateral of pain involved)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: 188Re-PTI-6D2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Krill Oil and Resistance Exercise in Older Adults
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Vegetable oil|DIETARY_SUPPLEMENT: Krill oil|OTHER: Home-based resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: 300mg vandetanib|DRUG: 150mg vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Multicenter Randomized Controlled Study of Simultaneous Cognitive Training With Transcranial Magnetic Stimulation in the Treatment of VaD-MCI Patients
Status: NOT_YET_RECRUITING
Conditions: VaD-MCI
Interventions: DEVICE: simultaneous cognitive training with transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afamelanotide in Patients Suffering From Polymorphic Light Eruption (PLE)
Status: COMPLETED
Conditions: Polymorphic Light Eruption
Interventions: DRUG: Afamelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Combination Treatment With Excimer Laser, Clobex Spray, and Vectical Ointment in the Treatment of Psoriasis
Status: COMPLETED
Conditions: Chronic Stable Plaque Psoriasis
Interventions: DRUG: Clobex Spray|DRUG: Vectical Ointment|PROCEDURE: Excimer Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alba - a Mobile App to Provide Bereavement Support for Adolescents in Grief
Status: NOT_YET_RECRUITING
Conditions: Complicated Grief Disorder
Interventions: BEHAVIORAL: Alba - Youth in grief|BEHAVIORAL: Control website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine and Imatinib Mesylate as First-Line Therapy in Patients With Locally Adv. or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Flow Oxygenation Therapy and CPAP in Children With Bronchiolitis.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Bronchiolitis
Interventions: DEVICE: Optiflow Junior|DEVICE: Continous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitigating ACEs in Pediatric Primary Care: Cohort #2 With 6-24 Month Old Children
Status: COMPLETED
Conditions: Parenting|Violence|Child Abuse
Interventions: BEHAVIORAL: Discipline education|BEHAVIORAL: Cavity Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Hippotherapy Simulator in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Exercise
Interventions: OTHER: Therapeutic exercise program via hippotherapy mechanical stimulator|OTHER: Therapeutic home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
Status: UNKNOWN
Conditions: Implantation Failure|Infertility
Interventions: PROCEDURE: Endometrial Biopsy|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liquid Biopsy to Reduce Time to Treatment for Advanced Nonsquamous NSCLC Diagnosed at Outside Sites
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: Liquid biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Status: RECRUITING
Conditions: Stage III Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8
Interventions: RADIATION: External Beam Radiation Therapy|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Abiraterone|DRUG: Placebo for Enzalutamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)
Status: RECRUITING
Conditions: B Precursor Acute Lymphoblastic Leukemia|Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Xerostomia
Interventions: DRUG: Pilocarpine|PROCEDURE: ALTENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Pharmacist Intervention on the Use of Zostavax in a Community Pharmacy Setting
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: OTHER: Personalized letter|OTHER: Flyer advertisement|OTHER: Newspaper press release
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Valsartan Optimal Therapy Against Elevated Home Blood Pressure Research（VOYAGER）Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan 80mg daily|DRUG: Valsartan 160mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: sCD163 in PBC Patients - Assessment of Treatment Response
Status: RECRUITING
Conditions: Primary Biliary Cirrhosis|Liver Inflammation|Ursodeoxycholic Acid
Interventions: OTHER: Blood samples|DEVICE: Fibroscan|OTHER: Questionnaires|BIOLOGICAL: Liver biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: CYP450 Cocktail and Transporter Substrates with Pacritinib|DRUG: Part 2 -Group A Bosentan 125 mg (CYP450 3A4 inducer) with Pacritinib|DRUG: Part 2 Group B - Fluconazole (CYP450 3A4 inhibitor) with Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients
Status: UNKNOWN
Conditions: Aphasia, Broca
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS-r)|DEVICE: Placebo Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Deep-Slow Breathing Exercise and Cranial-Visceral Manual Therapy on ANS Parameters in Healthy Adults
Status: COMPLETED
Conditions: Autonomic Nervous System
Interventions: OTHER: Manual Therapy|OTHER: Deep-slow breathing|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Photobiomodulation in Salivary Analysis of Chronic Renal Failure Patients
Status: COMPLETED
Conditions: Xerostomia|Chronic Renal Failure
Interventions: RADIATION: Photobiomodulation|RADIATION: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Surgery in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|DRUG: paclitaxel|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma
Status: UNKNOWN
Conditions: Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Azacitidine|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alefacept for Prevention of Graft Versus Host Disease (GVHD)
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Alefacept (AMEVIVE®)|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Biomechanical Gait Analysis in Patients Post-Stroke
Status: COMPLETED
Conditions: CVA (Cerebrovascular Accident)|Stroke
Interventions: DEVICE: Body Weight Support Gait Training|OTHER: Traditional Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Drug-Drug Interaction Between IDX719 and Simeprevir in Healthy Participants (MK-1894-004)
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: IDX719|DRUG: Simeprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Lisdexamfetamine to Treat Binge Eating Disorder
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DRUG: lisdexamfetamine|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Tissue Adhesive Vs. Absorbable Suture Vs. Non-Absorbable Suture
Status: UNKNOWN
Conditions: Cyst of Face, Neck or Shoulder|Pilomatrixoma of Face, Neck or Shoulder
Interventions: DEVICE: standard suture (5-0 prolene), topical skin adhesive (dermabond), absorbable suture (5-0 Chromic gut)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture and Bee Venom Acupuncture on Patients With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DEVICE: acupuncture and bee venom acupuncture point injection|DEVICE: sham acupuncture and normal saline injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults with Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Regional Ventilation Distribution Using Electrical Impedance Tomography During Weaning From Mechanical Ventilation
Status: RECRUITING
Conditions: Acute Respiratory Failure|Mechanical Ventilation Complication|Ventilator-Induced Lung Injury|Weaning Failure
Interventions: DIAGNOSTIC_TEST: Weaning trial - Low support, high Positive end-expiratory pressure|DIAGNOSTIC_TEST: Weaning trial - Low support, zero positive end-expiratory pressure|DIAGNOSTIC_TEST: Weaning trial - Zero support, zero positive end-expiratory pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability Study of Lu AF11167 After Repeated Dosing in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Lu AF11167
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine in Osteomuscular Treatment
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: DRUG: ketoprofen and cyclobenzaprine association|DRUG: Cyclobenzaprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Prevention of Driver Gene Negative II-IIIa Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: chemotherapy plus TCM 1&ICIs plusTCM2 placebo|DRUG: chemotherapy plus TCM 1placebo &ICIs plus TCM2 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Acute Effect of ESWT and ESWT+KT on Pain and Grip Strength
Status: UNKNOWN
Conditions: Pain|Muscle Strength|Lateral Epicondylitis|Kinesio Taping
Interventions: DEVICE: ESWT|OTHER: Kinesiotaping Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Study on Vanguard Cruciate Retaining Versus Vanguard High Flex Posterior Stabilized Total Knee System in the Early Range of Motion
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Vanguard PS Knee|DEVICE: Vanguard CR Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Intensity Vibration (LIV) on Aromatase Inhibitor- Induced Musculoskeletal Dysfunction in Early Stage Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Macrodyne LivMD plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa
Status: COMPLETED
Conditions: Adenomatous Polyps
Interventions: DRUG: Eicosapentaenoic Acid (EPA)|PROCEDURE: Endoscopy|PROCEDURE: Biopsies taken|PROCEDURE: Clinical chemistry|PROCEDURE: Haematology|PROCEDURE: Physical examination|PROCEDURE: Vital signs|PROCEDURE: Urine pregnancy test|PROCEDURE: Completion of patient diary card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of E-cigarette Use on the Body
Status: ACTIVE_NOT_RECRUITING
Conditions: Cigarette Smoking-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Nitric Oxide Breath Test|PROCEDURE: Oscillometry|PROCEDURE: Spirometry|OTHER: Survey Administration|PROCEDURE: Endothelial function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily Prednisone Versus Pulsed Dexamethasone in Treatment-naïve Adult Patients With Immune Thrombocytopenia
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tub Bathing on Skin and Bilirubin Levels in Infants Undergoing Tunnel and LED of Phototherapy
Status: COMPLETED
Conditions: Newborn Jaundice
Interventions: OTHER: TUBE BATH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LX102 in Patients With Neovascular Age-Related Macular Degeneration (nAMD)
Status: RECRUITING
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: GENETIC: LX102 subretinal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Deferiprone in Paediatric Patients
Status: COMPLETED
Conditions: Chronic Iron Overload
Interventions: DRUG: Deferiprone, dose level 1|DRUG: Deferiprone, dose level 2|DRUG: Deferiprone, dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Anatomopathological Analysis and Clinical Evolution After Radiological Removal of Retrievable Vena Cava Filters
Status: COMPLETED
Conditions: Vena Cava Thrombosis
Interventions: BIOLOGICAL: Retrievable Inferior Vena Cava Filters (IVCF)|OTHER: Demographics data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antidepressant Safety in Kids Study
Status: COMPLETED
Conditions: Anxiety Disorders|Depressive Disorders|Eating Disorders|Obsessive Compulsive Disorder
Interventions: DRUG: Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p