pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Supplement on Cognitive Function and Brain Activity in Middle Age and Older Healthy Adults
Status: RECRUITING
Conditions: Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: PoZibio|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjunctive Duration-doubled tDCS for the Treatment of Depressive Patients With Suicidal Ideation
Status: RECRUITING
Conditions: Suicidal Ideation
Interventions: DEVICE: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: icosapent ethyl (IPE)|OTHER: gel cap placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Abemaciclib and Letrozole in Treating Patients With Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Endometrioid Adenocarcinoma
Interventions: DRUG: Abemaciclib|DRUG: Letrozole|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FX vs. ECG Guidance for PICC Insertion
Status: COMPLETED
Conditions: Long Term Antibiotics|Chemotherapy|Total Parenteral Nutrition
Interventions: DEVICE: ECG-EM Guidance|DEVICE: FX Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hypertonic Saline as Add on Therapy in Preschool Children With Acute Wheezing Attack.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: hypertonic saline-salbutamol combination|DRUG: Normal saline-salbutamol combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy vs. Supportive Psychotherapy With Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy adapted for Cystic Fibrosis (ACT with CF)|BEHAVIORAL: Supportive Psychotherapy (Treatment as Usual Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphoma
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|T-cell Prolymphocytic Leukemia|T-cell Large Granular Lymphocytic Leukemia|Peripheral T-cell Lymphoma, NOS|Angioimmunoblastic T-cell Lymphoma|Extranodal NK/T-cell Lymphoma, Nasal Type|Enteropathy-type Intestinal T-cell Lymphoma|Hepatosplenic T-cell Lymphoma
Interventions: BIOLOGICAL: anti-CD7 CAR-pNK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine + Bendamustine in Women With Pretreated Locally Advanced or Metastatic Her2-negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole (NEXIUM) vs. Surgery
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: esomeprazole|PROCEDURE: Laparoscopic fundoplication (surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Platelet-rich Fibrin|Macular Holes|Pterygium|Glaucoma
Interventions: PROCEDURE: PRF membrane tamponade surgery in macular hole|PROCEDURE: ILM peeling in macular hole|PROCEDURE: PRF membrane grafting in pterygium|PROCEDURE: Autologous conjunctival transplantation in pterygium|PROCEDURE: autologous PRF membrane grafting in trabeculectomy for glaucoma|PROCEDURE: Amniotic membrane in trabeculectomy for glaucoma|PROCEDURE: PRF membrane grafting incorneal ulcer|PROCEDURE: Amniotic membrane in corneal ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery
Status: RECRUITING
Conditions: Spine Deformity|Bone Graft; Complications|Adverse Events
Interventions: DEVICE: ABM/P-15 bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Group Wellness Interventions in TBI Partner Caregivers
Status: COMPLETED
Conditions: Traumatic Brain Injury|Partner Caregiver
Interventions: BEHAVIORAL: EnHAncing BehavIors through wellness TreatmentS (HABITS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Contraceptives on Cervico-Vaginal Mucosa
Status: COMPLETED
Conditions: Mucosal Inflammation|Contraceptive; Complications, Intrauterine
Interventions: DRUG: Copper IUD|DRUG: Etonogestrel implant|DRUG: Levonorgestrel IUS|DRUG: DMPA Sub-cutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Different Virtual Reality Methods in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Nintendo Wii Fit Balance exercises|OTHER: Balance Trainer Balance Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Compression and Exercise on Lymphedema Incidence in Patients With Gynecological Cancer
Status: COMPLETED
Conditions: Genital Neoplasms, Female|Lymphedema
Interventions: DEVICE: Bilateral leg compression stockings|BEHAVIORAL: Individualized exercise|BEHAVIORAL: Lymphedema risk reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: E-aid Sleep-focused TrEatment for Prevention of Major Depression (STEP-MD)
Status: UNKNOWN
Conditions: Insomnia|Depression|Self Harm
Interventions: BEHAVIORAL: e-aid Cognitive Behavior Therapy|BEHAVIORAL: e-aid Sleep Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melancholic Symptoms in Bipolar Depression and Responsiveness to Lamotrigine
Status: COMPLETED
Conditions: Depression|Bipolar Disorder|Bipolar Depression|Melancholia|Lamotrigine
Interventions: DRUG: Lamotrigine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease
Status: COMPLETED
Conditions: Steroid Refractory GVHD
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab at Either 500 or 750 mg/m2 Every Other Week for Recurrent or Metastatic Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Head and Neck|Squamous Cell Cancer
Interventions: BIOLOGICAL: cetuximab|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Oxytocin in the Perception of Faces
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Syntocinon (synthetic oxytocin)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria
Status: WITHDRAWN
Conditions: Hyperoxaluria|Nonalcoholic Fatty Liver Disease|Kidney Stone
Interventions: DRUG: BMN 255|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Overweight/Obese Men With T2DM or Prediabetes and Hypogonadism
Status: RECRUITING
Conditions: Fatty Liver|Overweight/Obesity|Prediabetes/Type2 Diabetes Mellitus|Hypogonadism, Male
Interventions: DRUG: Testosterone Undecanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Neuro Zti Cochlear Implant System Efficacy and Safety in Adults
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Hearing Loss, Cochlear|Deafness
Interventions: DEVICE: Neuro Zti|DEVICE: Neuro One
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine As Adjuvant to Ropivacaine for Brachial Plexus Block
Status: COMPLETED
Conditions: Local Anesthesia Adjuvants|Upper Extremity Fracture|Brachial Plexus Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory and Immune Response After High Intensity Exercise
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DIETARY_SUPPLEMENT: Fucoidan 500mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Therapy With Carfilzomib for the Antibody-Mediated Rejection Diagnosis in Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplant Rejection
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bone Marrow-Derived Stem Cells in Patients With Macular Degeneration
Status: COMPLETED
Conditions: Age Related Macular Degeneration and Stargartd
Interventions: OTHER: intravitreal injection of autologous bone marrow stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) With Osimertinib for the Treatment of Patients With Oligoprogressive EGFR Positive Non-small Cell Lung Carcinoma
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Osimertinib|PROCEDURE: Positron Emission Tomography|RADIATION: Stereotactic Body Radiation Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pharmacy Clinic on Diabetes Management
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Pharmacy Managed Diabetes Clinic (PMDC)|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial for Adults With Acquired Brain Injury
Status: COMPLETED
Conditions: Acquired Brain Injury|Traumatic Brain Injury|Stroke
Interventions: BEHAVIORAL: Adapted Hatha Yoga|BEHAVIORAL: Low-Impact Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting Conditions
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Mucociliary Clearance Defect
Interventions: OTHER: Baseline (Huff-Cough alone)|DEVICE: Oscillatory Positive Expiatory Pressure Device|DEVICE: Whole-Body Vibration Platform|DEVICE: High Frequency Chest Wall Oscillatory Vest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rituximab in Addition to Chemotherapy With Autologous Stem Cell Transplantation as Treatment Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma|POOR PROGNOSIS
Interventions: DRUG: Rituximab|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisone|DRUG: Granulocyte-colony-stimulating factor|DRUG: Mitoxantrone|DRUG: Cytarabine ARA-C|DRUG: Dexamethasone|DRUG: Carmustine BCNU|DRUG: Etoposide|DRUG: Melphalan|RADIATION: Radiotherapy|PROCEDURE: PBSC reinfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Visual Outcomes After Bilateral PanOptix Implantation in Patients With Previous Multifocal Contact Lens
Status: RECRUITING
Conditions: Cataract
Interventions: DEVICE: The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Safety, Tolerability, Pharmacokinetics, and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: ABT-SLV187|DRUG: Oral Levodopa/Carbidopa|DEVICE: Infusion Pump: CADD-Legacy® 1400 Pump|DEVICE: NJ-Tube: Silicon ED Tube|DEVICE: Adaptor: Hakko Adaptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cancer Home Life Intervention Study. A Randomised, Controlled Multicentre Trial and a Health Economic Evaluation
Status: COMPLETED
Conditions: Activities of Daily Living|Everyday Activities|Palliative Care|Cancer|Quality of Life
Interventions: OTHER: The Cancer Home Life Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study in Healthy Male Subjects to Assess the Absorption, Distribution, Metabolism and Excretion of [14C]-Labelled BIA 9-1067 and Metabolites
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: OPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Emricasan in Symptomatic Outpatients Diagnosed With Mild-COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Emricasan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled Vancomycin|DRUG: Placebo (Sterile Water)|DRUG: Rifampin|DRUG: Trimethoprim/Sulfamethoxazole (TMP/SMX)|DRUG: Doxycycline|DRUG: Mupirocin Intranasal Creme|DRUG: 4% chlorhexidine gluconate liquid skin cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Microwave Ablation Combined With Camrelizumab and Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer: a Multicenter, Open, Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Nsclc
Interventions: DRUG: Microwave ablation combined with Camrelizumab and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 99mTc-rhAnnexin V-128 a Phase I/IIa Study in Patients With Rheumatoid Arthritis (RA) or Ankylosing Spondylitis (AS)
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis
Interventions: DRUG: 99mTc-rhAnnexin V-128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SBRT (Stereotactic Body Radiation Therapy) vs. Surgery in High Risk Patients With Early Stage Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell-Lung|Non-Small Cell Lung Cancer|Nonsmall Cell Lung Cancer
Interventions: BEHAVIORAL: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30|BEHAVIORAL: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire LC-13|BEHAVIORAL: Modified Medical Research Council|BEHAVIORAL: EQ-5D|BEHAVIORAL: Center for Epidemiological Studies Depression Scale|BEHAVIORAL: Medical Outcomes Study Social Support Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Combined General/Regional Anesthesia on Cancer Recurrence in Patients Having Lung Cancer Resections
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: General anesthesia with opioid analgesia|PROCEDURE: Combined general/epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Lapaquistat Acetate in Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate|DRUG: Lapaquistat acetate and additional lipid-lowering therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Medications in Patients With Hypogonadism
Status: COMPLETED
Conditions: Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: Testosterone enanthate (Sustanon 250 mg)|DRUG: Human chorionic gonadotropin (hCG) (Pregnyl 5000 IU)|DRUG: Testosteron gel (Testojel 50 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age Related Macular Degeneration|Macular Degeneration|AMD
Interventions: DRUG: HuCNS-SC cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute
Interventions: DRUG: Cyclophosphamide|DRUG: Daunorubicin|DRUG: Vincristine|DRUG: Prednisolone|DRUG: L-asparaginase|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Mercaptopurine|DRUG: Doxorubicin|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of 3 New Formulations of Premarin/MPA Compared With Premarin/MPA (Prempro)
Status: COMPLETED
Conditions: Postmenopause
Interventions: DRUG: Premarin/MPA 0.45 mg/1.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation in the Treatment of Addiction
Status: UNKNOWN
Conditions: Alcohol Addiction
Interventions: OTHER: Verum rTMS|OTHER: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteral Granulocyte Colony Stimulating Factor and Erythropoietin Early in Life Increases Feeding Tolerance in Preterm Infants: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Feeding Intolerance|Necrotizing Enterocolitis
Interventions: DRUG: recombinant human G-CSF, and rhEPO|DRUG: rh G-CSF|DRUG: rh EPO|DRUG: rh G-GSF and rh EPO together|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: dacarbazine|DRUG: vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct and Alternating Stimulation of the Prefrontal Cortex for Cognitive Improvement in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Cognitive Dysfunction
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|DEVICE: transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dynamic Balance, Flexibility and Agility as Predictors of Lower-extremity Injury in Football Players
Status: COMPLETED
Conditions: LOWER-LIMB INJURY
Interventions: DIAGNOSTIC_TEST: Y Balance Test|DIAGNOSTIC_TEST: Sit and Reach Test|DIAGNOSTIC_TEST: "Maximum Legs Abduction" Test|DIAGNOSTIC_TEST: S_RAG (reactive agility)" Test|DIAGNOSTIC_TEST: S_CODS (change of direction speed) Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Evaluation of Dexmedetomidine for EBUS-TBNA
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the WallFlex™ Biliary Partially-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction
Status: COMPLETED
Conditions: Biliary Strictures Caused by Malignant Neoplasms
Interventions: DEVICE: WallFlex™ Biliary Partially-Covered Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of Tuberculosis Treatments by Oral Inhalation
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: ABCD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study for Imaging of the Esophagus Using a Tethered Capsule OCT Endomicroscopy in the Primary Care Setting
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: MGH OCT Imaging Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Use of BCAA-rich Protein Supplements for Chronic Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DIETARY_SUPPLEMENT: BCAA supplement|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Powered Wheelchair Standing Devices: An Exploratory Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy|Spinal Muscular Atrophy|Spinal Cord Injuries|Spina Bifida|Development Delay|Genetic Disease
Interventions: DEVICE: Power Wheelchair Standing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee
Status: COMPLETED
Conditions: Chronic Pain|Osteoarthritis of the Knee
Interventions: DRUG: Buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Vaccine: Semi-allogeneic Human Fibroblasts (MRC-5) Transfected With DNA
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: BIOLOGICAL: Semi-allogenic human fibroblast (MRC-5) transfected with DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Three Doses of Aripiprazole in Patients With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Aripiprazole|DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Irinotecan Plus Epirubicin as the Second-line Chemoregime for Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stage IV Gastric Cancer With Metastasis
Interventions: DRUG: second line chemoregime for advanced gastric cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Use of Xylitol-wipes to Prevent Dental Caries
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: xylitol wipe|DIETARY_SUPPLEMENT: placebo wipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Integration of Ag-RDTs for COVID-19 in MNCH, HIV and TB Services in Cameroon and Kenya
Status: COMPLETED
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Integration of SARS-CoV 2 Testing in HIV, MNCH and TB Clinics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pioglitazone and Insulin Resistance in ADT
Status: WITHDRAWN
Conditions: Prostate Cancer|Insulin Resistance|Diabetes Mellitus, Type 2|Androgen Deficiency
Interventions: DRUG: Pioglitazone 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)
Status: TERMINATED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: CNTO 148 (Golimumab)|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma
Status: RECRUITING
Conditions: Gastroesophageal Adenocarcinoma
Interventions: DRUG: Paclitaxel|DRUG: Ramucirumab|DRUG: Zanidatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Atogepant Tablets to Assess Change in Disease Activity in Adult Japanese Participants With Episodic Migraine
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine
Interventions: DRUG: Atogepant|DRUG: Placebo for Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avanz Phleum Pratense Maintenance Dose
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: DRUG: Avanz Phleum pratense|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RHIV A Pilot Study Refractory or Intolerant to Highly Active Antiretroviral Therapy (HAART)
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: PROCEDURE: Extracorporeal photochemotherapy with UVADEX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gemcitabine Plus Nab-paclitaxel as Secondary Chemotherapy in Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma|Chemotherapy Effect
Interventions: DRUG: Chemotherapy (Gemcitabine + nab-paclitaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramelteon for Treatment of Adult Patients With ADHD-Related Insomnia
Status: COMPLETED
Conditions: ADHD With Sleep Onset Insomnia
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacology Trial of Brexpiprazole Once-weekly (QW) Formulation Administered as Single and Multiple Oral Doses
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: 2mg conventional tablet, once-weekly tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer|Pain, Musculoskeletal
Interventions: DRUG: Levobupivacaine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Release and Nerve Flossing Technique on Pain and Disability in Patients With Lumbar Radiculopathy
Status: RECRUITING
Conditions: Lumbar Radiculopathy
Interventions: OTHER: Nerve flossing technique|OTHER: Myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of VA106483 in Males With Nocturia and Benign Prostatic Hypertrophy (BPH)
Status: COMPLETED
Conditions: Nocturia|Benign Prostatic Hypertrophy (BPH)
Interventions: DRUG: VA106483
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Novel Transperineal Targeted Fusion Biopsy System to Conventional Transrectal Targeted Fusion Biopsy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Ultrasound (US) Targeted Fusion Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and Lenvatinib for Resectable Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Pembrolizumab+Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Green Tea Attenuates Pressure Reduction Induced by a Session of Physical Exercise
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: GT+Ex|DIETARY_SUPPLEMENT: PL+Ex|DIETARY_SUPPLEMENT: Green Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy, Pharmacokinetics and Safety Comparison of Salmeterol Inhalation Powder Administered Via the HandiHaler® 2 and Serevent® Diskus® in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol xinafoate|DRUG: Serevent® Diskus®|DRUG: Placebo (HandiHaler®)|DRUG: Placebo (Diskus®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Warming on Postoperative Hypothermia
Status: COMPLETED
Conditions: Preventing Hypothermia|Perioperative Hypothermia
Interventions: OTHER: forced air warming group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open-Label,Non-Randomized Trial of Cisplatin Chemotherapy in BRCA1-Positive Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: BRCA1 Mutation|Metastatic Breast Cancer
Interventions: DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Every Newborn-Reach Up Early Education Intervention for All Children- a Parent Group Intervention for School Readiness in Bangladesh, Nepal, and Tanzania
Status: ACTIVE_NOT_RECRUITING
Conditions: Child Development|Child Development Disorder
Interventions: BEHAVIORAL: Pre-Primary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Guided Internet-delivered Individually-tailored ACT-influenced CBT Intervention to Improve Psychosocial Outcomes in Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: BEHAVIORAL: iACT-BC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Should a Standard Lymphadenectomy Include the No. 16 Lymph Nodes for Patients With Pancreatic Head Adenocarcinoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Extended Lymphadenectomy|PROCEDURE: Standard Lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPV16 E6 TCR T Cells for Cervical Carcinoma
Status: RECRUITING
Conditions: Cervical Carcinoma
Interventions: BIOLOGICAL: TC-E202 cells|DRUG: IL-2|DRUG: Fludarabine|DRUG: Cyclophosphamide Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Autonomic Nerve Improvement and Pacemaker Therapy in Patients With Sinus Bradycardia
Status: NOT_YET_RECRUITING
Conditions: Sinus Bradycardia
Interventions: PROCEDURE: Cardiac autonomic nerve modification|PROCEDURE: Pacemaker implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ramosetron on Bowel Motility After Colorectal Resection
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase II Study of LAZE rtiNib Alone Versus Lazertinib Plus bevaCizumab for NSCLC With EGFR + & Smoker
Status: RECRUITING
Conditions: Lazertinib
Interventions: DRUG: Lazertinib|DRUG: Bevacizumab Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines, and Juvéderm® Ultra XC for the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds, Wrinkles
Interventions: DEVICE: TEOSYAL® RHA Global Action|DEVICE: TEOSYAL® RHA Deep Lines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dextenza With ILUX for Treatment of MGD
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction|Evaporative Dry Eye
Interventions: DRUG: Dexamethasone, 0.4mg|DRUG: Prednisone acetate|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remifentanil in Ventilated Preterm Infants
Status: TERMINATED
Conditions: Preterm Infants|Mechanical Ventilator Care
Interventions: DRUG: remifentanil infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Regenexx SD® procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK
Status: UNKNOWN
Conditions: Keratoconjunctivitis Sicca
Interventions: PROCEDURE: PRK with conjunctival impression cytology before and after surgery|PROCEDURE: LASIK with conjunctival impression cytology before and after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic|Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate (SZC)|DRUG: Placebo|DRUG: Lisinopril|DRUG: Valsartan|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Surgery Start Time on Postoperative Interleukin-6, Interleukin-8, and Cortisol
Status: COMPLETED
Conditions: Hemiarthroplasty|Arthroplasty, Replacement, Hip
Interventions: PROCEDURE: Total hip replacement|PROCEDURE: Hemi-arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Functional MRI Neurofeedback to Modulate Self-blame in Major Depressive Disorder
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: fMRI neurofeedback (A)|OTHER: fMRI neurofeedback (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maca Extract in Sexual Dysfunction Male
Status: NOT_YET_RECRUITING
Conditions: Sexual Dysfunction Male
Interventions: DIETARY_SUPPLEMENT: Maca|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Optimal Anemia Management in End-stage Renal Disease: The Anemia Control Model (ACM) Trial
Status: TERMINATED
Conditions: Anemia|End Stage Renal Disease
Interventions: DEVICE: Anemia Control Model (ACM)|DRUG: IV iron|DRUG: Erythropoiesis-Stimulating Agent (ESA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Camrelizumab Combined With Concurrent Chemoradiation in Patients With Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: Camrelizumab|DRUG: Cisplatin or Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
Status: RECRUITING
Conditions: Dysphagia|Aspiration|Brief Resolved Unexplained Event (BRUE)|Apparent Life Threatening Event (ALTE)
Interventions: DIETARY_SUPPLEMENT: Thin liquid swallows|DIETARY_SUPPLEMENT: Slightly thickened liquid swallows|DIETARY_SUPPLEMENT: Mildly thickened liquid swallows|DIETARY_SUPPLEMENT: Moderately thickened liquid swallows
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia
Status: COMPLETED
Conditions: Pain, Chronic|Pain, Acute|Central Sensitisation|Neuroinflammatory Response
Interventions: DIETARY_SUPPLEMENT: Palmithylethanolamid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Expression in the Perioperative Period of Cataract Surgery
Status: UNKNOWN
Conditions: Cataract|Surgery|Eye Pain
Interventions: PROCEDURE: First eye (FE)|PROCEDURE: Second eye (SE)|DRUG: Steroids eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA)
Status: RECRUITING
Conditions: Paraganglioma|Pheochromocytoma
Interventions: DRUG: Lanreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects
Status: WITHDRAWN
Conditions: Asthma, Bronchial|Lung Diseases, Obstructive|Respiratory Tract Diseases|Bronchial Diseases
Interventions: DRUG: PF-00610355|DRUG: PF - 00610355|OTHER: Placebo|DRUG: PF - 00610355
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-Port Versus Single-port Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: 4-Ports Cholecystectomy (4PC)|PROCEDURE: Single-Port Cholecystectomy (SPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PG2 Injection for the Treatment of moderate-to Severe Fatigue in Breast Cancer Patients
Status: UNKNOWN
Conditions: Cancer-related Fatigue
Interventions: DRUG: PG2 Lyo. Injection 500mg|DRUG: Placebo 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency and Risk Factors of Bleeding in Patients With Chronic Kidney Disease Receiving Anticoagulants
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases Receiving Anticoagulants
Interventions: DIAGNOSTIC_TEST: serum creatinine|DIAGNOSTIC_TEST: INR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robotic Constraint Lokomat Training for Gait Rehabilitation in Patients With Stroke
Status: UNKNOWN
Conditions: PHYSICAL THERAPY TECHNIQUES
Interventions: OTHER: The Lokomat® Pro Hocoma USA & Conventional physical therapy|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Buffered Lidocaine Versus Nonbuffered Lidocaine on Pain Scores During Infiltration for Vulvar Biopsies
Status: COMPLETED
Conditions: Genital Diseases, Female
Interventions: DRUG: Non-Buffered Lidocaine|DRUG: Buffered Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Modulating Prospective Memory in Older Adults With Non-invasive Brain Stimulation
Status: COMPLETED
Conditions: Healthy Aging
Interventions: DEVICE: Non-invasive brain stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Versus Interval Postpartum Use of the Levonorgestrel Contraceptive Implants: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Contraceptive Implant Utilization|Lactation
Interventions: DEVICE: Jadelle|DEVICE: Jadelle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Adenocarcinoma|Stage IA Uterine Corpus Cancer|Stage IB Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage IIIA Uterine Corpus Cancer|Stage IIIB Uterine Corpus Cancer|Stage IIIC Uterine Corpus Cancer|Stage IVA Uterine Corpus Cancer|Stage IVB Uterine Corpus Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Internal Radiation Therapy|RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT