pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Erythropoietin (EPO) Administration Schedule
Status: COMPLETED
Conditions: Chronic Renal Failure|Anaemia
Interventions: DRUG: recomon (Epoetin Beta)|DRUG: recomon (Epoetin Beta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combination Therapy of Aliskiren/Amlodipine or Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Stage II Hypertension
Status: COMPLETED
Conditions: Stage II Hypertension
Interventions: DRUG: Aliskiren/Amlodipine (150/5 mg/day, 300/10 mg/day) , Aliskiren/Amlodipine/Hydrochlorothiazide (300/10/12.5 mg/day, 300/10/25 mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Paricalcitol on the Treatment of Secondary Hyperparathyroidism in Calcitriol Resistant Dialysis Subjects
Status: TERMINATED
Conditions: Secondary Hyperparathyroidism|Dialysis
Interventions: DRUG: Calcitriol|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of tDCS on a Motor-cognitive Dual-task Performance of Parkinson's Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin (VIT) for Vigilance Study
Status: RECRUITING
Conditions: Cognitive Change|Stress
Interventions: DIETARY_SUPPLEMENT: Colon-delivered multivitamin supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison Between Mechanical Intracanal (ML) Lithotripsy and Electrohydraulic Intracolangioscopic (EHL) Lithotripsy in the Treatment of Difficult Main Biliary Tract Lithiasis
Status: UNKNOWN
Conditions: Gallstone|Lithiasis
Interventions: PROCEDURE: ML lithotripsy|PROCEDURE: EHL lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lot-to-lot Consistency of Sci-B-Vac™ in Adults
Status: COMPLETED
Conditions: Hepatitis B Vaccines
Interventions: BIOLOGICAL: Hepatitis B Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Childbirth Education and Birth Plan on Birth Self Efficacy in Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Related|Self Efficacy
Interventions: OTHER: childbirth education|OTHER: childbirth education and was subjected to a birth plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Neuroprotective Strategy for Ischemic Stroke After Thrombectomy Followed by DELP (INSIST-DELP)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Delipid Extracorporeal Lipoprotein filter from Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab, Bevacizumab With Paclitaxel for HER2-positive Gastric Cancer in a Second-line Therapy
Status: RECRUITING
Conditions: HER2-positive Advanced Gastric Cancer
Interventions: DRUG: trastuzumab, bevacizumab with paclitaxel (triple combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What is the Optimal antiplatElet and Anticoagulant Therapy in Patients With Oral Anticoagulation Undergoing revasculariSaTion 2.
Status: UNKNOWN
Conditions: Atrial Fibrillations|Heart Valve Prostheses|Acute Coronary Syndromes|Coronary Artery Diseases|Stroke|Bleeding|Myocardial Infarction
Interventions: DRUG: Combination of chronic oral anticoagulation and a P2Y12 inhibitor with or without aspirin.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiemetic Therapy With or Without Olanzapine in Preventing Chemotherapy-Induced Nausea and Vomiting in Patients With Cancer Receiving Highly Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Hematopoietic/Lymphoid Cancer|Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Olanzapine|DRUG: Chemotherapy (cisplatin or cyclophosphamide and doxorubicin)|DRUG: Antiemetic treatment (ondansetron or granisetron or palonosetron; plus dexamethasone; plus fosaprepitant or aprepitant)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reconvalescent Plasma/Camostat Mesylate Early in SARS-CoV-2 Q-PCR (COVID-19) Positive High-risk Individuals
Status: COMPLETED
Conditions: Corona Virus Infection|SARS-CoV-2 Infection|SARS-CoV-2 PCR Test Positive|SARS-CoV-2 Acute Respiratory Disease
Interventions: BIOLOGICAL: Convalescent plasma|DRUG: Camostat Mesilate|DRUG: Placebo for Camostat Mesilate|OTHER: Standard of Care (SoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma
Status: RECRUITING
Conditions: Normal Tension Glaucoma|Cataract
Interventions: PROCEDURE: Phaco|PROCEDURE: Phaco+ECP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Inhaled Aromatherapy on Chemotherapy Induced Nausea (CINV) and Vomiting
Status: TERMINATED
Conditions: Nausea|Vomiting
Interventions: OTHER: Peppermint Essential Oil, Ginger Essential Oil, or Pure Vanilla Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Upadacitinib|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Additional Nebulized Amikacin in Ventilator-Associated Pneumonia Caused by Gram Negative Bacteria
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: DRUG: Amikacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of AUY922 vs. Comparators in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Advanced Gastric Cancer|Gastro-esophageal Junction Cancer
Interventions: DRUG: AUY922|DRUG: Docetaxel|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAmucirumab Combined wIth Standard Nab-paclitaxel and Gemcitabine as First-line Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selected Chemotherapy Combined Immunotherapy Treated High Risk Patient After NCRT in Resected Locally Advanced ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tirelizumab|DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Neoadiuvant radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Cardiac Rehabilitation Participation in Women and Men
Status: COMPLETED
Conditions: Myocardial Infarction|Unstable Angina|Coronary Disease
Interventions: BEHAVIORAL: MD-endorsed Cardiac Rehabilitation referral|BEHAVIORAL: Standard Cardiac Rehabilitation referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Partial Menisectomy
Status: COMPLETED
Conditions: Meniscal Tear
Interventions: OTHER: Isokinetic eccentric exercises|OTHER: Isotonic eccentric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AESCULAP® Plasmafit® Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Rheumatic Arthritis|Degenerative Osteoarthritis
Interventions: DEVICE: Plasmafit® Vitelene® Vitamin E
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Observational Study (Called RETAF-PS) Using a Patient Survey to Learn More About Treatment Outcomes in Patients With Irregular and Often Rapid Heartbeat (Atrial Fibrillation) Treated With Apixaban in a Real World Setting
Status: COMPLETED
Conditions: Prevention of Thromboembolic Events|Atrial Fibrillation
Interventions: DRUG: Apixaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alpha-GPC and Physical and Cognitive Performances in Volleyball Players.
Status: COMPLETED
Conditions: Athletic Performance
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: [18F]-DPA-714 PET/CT (Positron Emission Tomography/Computerized Tomography) in Triple Negative Breast Cancers
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: [18F]-DPA-714 PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Dexmedetomidine for Cesarean Section
Status: COMPLETED
Conditions: Breast Feeding|Analgesia Obstetrical|Postoperative Pain
Interventions: DRUG: Normal Saline|DRUG: Dexmedetomidine 0.03ug/kg/h|DRUG: Dexmedetomidine 0.05ug/kg/h|DRUG: Dexmedetomidine 0.08ug/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenogenic Collagen Matrix and Subepithelial Connective Tissue Graft in the Treatment of Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession Localized Moderate
Interventions: PROCEDURE: (XCM)+(CAF)|PROCEDURE: (SCTG)+(CAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Lymphoma, B-Cell|Autologous Stem Cell Transplantation
Interventions: OTHER: Apheresis|OTHER: Autologous Stem Cell Transplantation|DRUG: CAR-T Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Birinapant and Carboplatin in Treating Patients With Recurrent High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: WITHDRAWN
Conditions: High Grade Fallopian Tube Serous Adenocarcinoma|High Grade Ovarian Serous Adenocarcinoma|Primary Peritoneal High Grade Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Birinapant|DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: capecitabine|DRUG: fluorouracil|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYP4A11 and CYP4F2 Gene Variants as Makers of Cardiovascular Adverse Events of Non-steroidal Anti-inflammatory Drugs
Status: COMPLETED
Conditions: Drug-Related Side Effects and Adverse Reactions
Interventions: DRUG: Diclofenac|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi Sarcoma
Status: COMPLETED
Conditions: AIDS-Related Kaposi Sarcoma|HIV Infection|Recurrent Kaposi Sarcoma
Interventions: DRUG: Bortezomib|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment
Status: COMPLETED
Conditions: Dentin Sensitivity|Periodontal Diseases
Interventions: DRUG: In-office and at home Colgate sensitive pro-relief - CSPR|DRUG: In-office Villevie® prophy paste + Colgate Toothpaste|PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth and Memory Study
Status: RECRUITING
Conditions: Chemotherapy-related Cognitive Dysfunction
Interventions: BEHAVIORAL: Memory and Attention Adaptation Training (MAAT)|BEHAVIORAL: Supportive Therapy (ST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Evaluate the Impact of Varying Crystalline Polymorph Forms for the Commercial Oral Capsule Formulation of 10-mg Lenvatinib in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lenvatinib 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation
Status: RECRUITING
Conditions: Cervical Spinal Cord Injury
Interventions: DEVICE: Brain-Computer Interface|DEVICE: Sham Brain-Computer Interface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Interactive Digital Healthcare System in Frozen Shoulder; Randomized Controlled Trial
Status: COMPLETED
Conditions: Frozen Shoulder
Interventions: DEVICE: Uincare Homeplus|OTHER: Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HFNC Versus NCPAP/ NPPV in Infants With Severe Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DEVICE: nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: PicoPrep|DRUG: HalfLytely|DRUG: bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dyson Air Purifier in Improving Asthma Control
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Dyson Pure Cool - Active Purifier|DEVICE: Dyson Pure Cool - Placebo purifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study
Status: COMPLETED
Conditions: Acute Exacerbation|Idiopathic Pulmonary Fibrosis|Home Spirometry
Interventions: OTHER: Home spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL
Status: RECRUITING
Conditions: Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: BAFFR-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol for Reducing Drinking in Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Cannabidiol Cap/Tab|DRUG: Placebo Cap/Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Vasoconstriction in Postural Tachycardia Syndrome
Status: COMPLETED
Conditions: Postural Tachycardia Syndrome
Interventions: DRUG: Losartan|DRUG: Ascorbic Acid (Vitamin C)|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Best Available Therapy With or Without Meropenem for Bloodstream Infections by Enterobacterales With High Level of Resistance to Carbapenems
Status: TERMINATED
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection|Bloodstream Infection
Interventions: DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAD EYE Detection of Remaining Lesions After EMR
Status: RECRUITING
Conditions: Colorectal Dysplasia|Colorectal Neoplasms
Interventions: DIAGNOSTIC_TEST: EMR with CAD-Eye™|DIAGNOSTIC_TEST: EMR without CAD-Eye™|DIAGNOSTIC_TEST: Follow-up colonoscopy with CAD-Eye™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Doravirine and Weight Gain in Antiretroviral Naive
Status: WITHDRAWN
Conditions: Body Weight Changes|Human Immunodeficiency Virus|ART|Obesity|Minority Health|BMD|Metabolic Syndrome|Fasting
Interventions: DRUG: DOR/3TC/TDF|COMBINATION_PRODUCT: DOR + FTC/TAF|DRUG: BIC/FTC/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Function of NobelSpeedy Shorty and Brånemark System® Mk III Shorty Implants in Daily Use
Status: COMPLETED
Conditions: Partial Edentulism|Complete Edentulism
Interventions: DEVICE: Shorty implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Use in Adolescents and Adults With Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Growth Hormone|PROCEDURE: Whole body Protein Turnover Study|PROCEDURE: Dual Energy X-ray Absorptiometry (DEXA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology
Status: COMPLETED
Conditions: Pain Score
Interventions: OTHER: the laying of the gastric tube and a group using the holed baby bottle nipple, the feeding tube ideally positioned at the center of the intersection pharyngeal|OTHER: the laying of the gastric tube and a group with simple non-nutritive suction, the feeding tube passing next to the newborn's personal pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Usability of Intranasal Glucagon in Treatment of Hypoglycemia
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus|Drug-Specific Antibodies
Interventions: DRUG: Nasal Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western Ukraine
Status: COMPLETED
Conditions: Abortion, Therapeutic
Interventions: DRUG: Mifepristone|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Meth-OD: A Study of IXT-m200 in Patients With Toxicity From Methamphetamine Overdose
Status: TERMINATED
Conditions: Methamphetamine Intoxication (Disorder)
Interventions: BIOLOGICAL: IXT-m200|DRUG: Lorazepam|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Rapid Airway Management Positioner
Status: COMPLETED
Conditions: Endotracheal Intubation|Rapid Airway Management Positioner
Interventions: DEVICE: Laryngoscopy with RAMP|DEVICE: Laryngoscopy without RAMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Effects of Propofol Versus Sevoflurane Anesthesia
Status: RECRUITING
Conditions: General Anesthetic Drug Adverse Reaction
Interventions: DRUG: Propofol 10 MG/ML Injection|DRUG: Sevoflurane Inhalation Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Therapeutic Induction of Endogenous Antibiotics
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: Sodium Butyrate|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Midwife-led Education Based on Pender's Health Promotion Model on Perinatal Mental Health of Migrant Women
Status: NOT_YET_RECRUITING
Conditions: Mental Health|Perinatal Care
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Decreasing Suicide Risk Among Service Members With Posttraumatic Stress
Status: COMPLETED
Conditions: Suicide|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Written Exposure Therapy -for Suicide|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticin for the Treatment of Coronary Lesions With Drug Eluting Ballons
Status: RECRUITING
Conditions: Chronic Coronary Syndrome
Interventions: DEVICE: Magic Touch drug eluting balloon based strategy|DEVICE: Drug-eluting stent-based strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Normative Data of Vestibular and Postural Function in Danish Children
Status: NOT_YET_RECRUITING
Conditions: Children, Only|Vestibular Function
Interventions: DIAGNOSTIC_TEST: video Head Impulse Test|DIAGNOSTIC_TEST: Cervical Vestibular Evoked Myogenic Potential|DIAGNOSTIC_TEST: Ocular Vestibular Evoked Myogenic Potential|DIAGNOSTIC_TEST: Computerized Dynamic Posturography|OTHER: Dizziness Handicap Inventory for patient caregivers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of a Gamified Attention Bias Modification Training in Anxious Youth
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Active Attention Bias Modification Training|BEHAVIORAL: Placebo Attention Bias Modification Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of IVS3 for Upper Limb Motor Recovery
Status: NOT_YET_RECRUITING
Conditions: Neglect, Hemispatial|Stroke, Cardiovascular|Mirror Movement|Motor Activity
Interventions: DEVICE: Intensive Visual Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.
Status: COMPLETED
Conditions: Hypogonadism|Obesity
Interventions: DRUG: liraglutide|DRUG: Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants
Status: RECRUITING
Conditions: Venous Thromboembolism
Interventions: DRUG: REGN7508|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Modern Breath Sampling System (the Pneumopipe® Combined With an Array of E-nose Sensors) for the Prediction of Treatment Response in Persistent Asthmatic Children
Status: NOT_YET_RECRUITING
Conditions: Asthma in Children
Interventions: DEVICE: Pneumopipe® (European patent 12425057.2, Rome, Italy)|OTHER: Other assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing the Impact of Isokinetic Muscular Strengthening in Eccentric Mode in the Medical Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Unilateral Knee Osteoarthritis
Interventions: OTHER: Exercise in eccentric or concentric mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Treatment of Autoimmune Thrombocytopenia (AITP)
Status: COMPLETED
Conditions: Autoimmune Disease|Autoimmune Hemolytic Anemia|Thrombocytopenia
Interventions: DEVICE: Isolex 300i
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Clarithromycin|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Wireless Disposable SpO2 Sensor Hypoxia Testing Part 1, Non-invasive Development Test for the New LED Platform
Status: NOT_YET_RECRUITING
Conditions: SpO2 \(Peripheral Oxygen Saturation\) Measurement Validation
Interventions: DEVICE: SpO2 Sensor Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Neural Tension Versus Neural Sliding Technique on Cervical Radiculopathy.
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Neural Tension Technique(ulnar, median, radial)|OTHER: Neural Slider Technique (ulnar, median, radial)|OTHER: Neural Tension Technique and Neural Sliding Technique(ulnar, median, radial)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of the Efficiency of ESWT and Ozone Injection in Patients With Chronic Plantar Fasciitis
Status: RECRUITING
Conditions: Plantar Fascitis
Interventions: DEVICE: Ozone Generator|DEVICE: Extracorporeal shock wave therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy
Status: RECRUITING
Conditions: Metachromatic Leukodystrophy|Adrenoleukodystrophy
Interventions: GENETIC: transduced CD34+ hematopoietic stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Bone marrow transplantation|DRUG: Cytoxan|DRUG: testosterone cypionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
Status: COMPLETED
Conditions: Gynecologic Cancer|Chemotherapy-induced Peripheral Neuropathy
Interventions: BEHAVIORAL: Cryocompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Exercise Rehabilitation Efficacy Outcomes Veterans Peripheral Artery Disease
Status: RECRUITING
Conditions: Peripheral Artery Disease (D058729)|Oxidative Stress (D018384)|Inflammation (D007249)
Interventions: DIETARY_SUPPLEMENT: PB125|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Exercise Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Evaluation Study of the Efficacy and Safety of TLA Gut™ Leukapheresis Treatment in Patients With Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis (UC)
Interventions: DEVICE: TLA Gut™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tenofovir Alafenamide Fumarate Tablets (TAF) in Blocking Mother-to-child Transmission of Hepatitis B Virus
Status: UNKNOWN
Conditions: Hepatitis B Virus|Mother to Child Transmission
Interventions: DRUG: Tenofovir Alafenamide Fumarate tablets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Amiodarone and Ranolazine Together in Patients With Angina
Status: UNKNOWN
Conditions: Chronic Stable Angina|Coronary Artery Disease|Atrial Fibrillation|Ventricular Tachycardia
Interventions: DRUG: ranolazine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Cancer Non-resectable|Pancreatic Ductal Adenocarcinoma, PDAC
Interventions: DRUG: surufatinib combined with gemcitabine plus nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase1 Study of Gemcitabine HCl Oral Formulation(D07001-F4) in Patients With Advanced Solid Malignancies and Malignant Lymphomas
Status: COMPLETED
Conditions: Advanced Solid Malignancies|Malignant Lymphomas
Interventions: DRUG: Gemcitabine HCl Oral Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Second Trial of the Abbreviated Protocol Two-Stage Exchange
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosthetic-joint Infection
Interventions: COMBINATION_PRODUCT: VT-X7 Treatment System|PROCEDURE: Two-stage exchange arthroplasty|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community
Status: ENROLLING_BY_INVITATION
Conditions: Frailty|Obesity|Sarcopenia|Sarcopenic Obesity|Gait Speed
Interventions: DIAGNOSTIC_TEST: 10 Meter Walk Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prognostic Value of Arterial Spin Labeling Brain Perfusion MRI in Term Neonates With Hypoxic-ischemic Encephalopathy
Status: COMPLETED
Conditions: Neonatal Hypoxic Ischemic Encephalopathy
Interventions: DEVICE: Arterial Spin Labeling sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Percutaneous Electrical Stimulation, Education and Exercise Program in Patients With Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Therapeutic exercise|OTHER: Pain education|OTHER: Percutaneous electrical stimulation|OTHER: Transcutaneous electrical stimulation|OTHER: Placebo stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy
Status: TERMINATED
Conditions: Neuropathy|Peripheral Neuropathy|Neuropathic Pain|Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Nicotine Transdermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of a Valsartan Based vs an Amlodipine Based Treatment Strategy in naïve Patients With Stage 1 or Stage 2 Hypertension or in Patients Uncontrolled on Current Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: ITV Extension Study
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: recombinant fowlpoxvirus (rFPV) expressing HIV gag-pol antigens|BIOLOGICAL: HIV gag-pol antigens and interferon-gamma (IFN-y)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prevention of High Altitude Pulmonary Edema
Status: COMPLETED
Conditions: High Altitude Pulmonary Edema
Interventions: DRUG: dexamethasone 8 mg bid|DRUG: tadalafil 10mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Interactive Guided Ultrasound Examinations Done by Non-experts of Ultrasound Imaging
Status: COMPLETED
Conditions: Cardiac Disease|Heart Failure|Cardiac Ischemia
Interventions: DEVICE: TransThoracic Echocardiography imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobilising Patients With Severe Brain Injury in Intensive Care
Status: RECRUITING
Conditions: Brain Injury Traumatic Severe|Subarachnoid Hemorrhage|Intracranial Hematoma
Interventions: DEVICE: Mobilisation using the Sara Combilizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults
Status: COMPLETED
Conditions: Sarcopenia
Interventions: BEHAVIORAL: Endurance exercise|BEHAVIORAL: Resistance exercise|BEHAVIORAL: Control/Combined training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liver Enzymes and Metabolic Risk Factors Response to Laser Acupuncture Versus Cupping Therapy in Fatty Liver
Status: RECRUITING
Conditions: Fatty Liver
Interventions: DEVICE: laser acupuncture|OTHER: wet cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation and Expansion Study Of SHR-1916 In Subjects With Locally Advanced Or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: SHR-1916
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Full Versus Fractional Doses of COVID-19 Vaccines Given as a Booster in Adults in Australia - Mongolia, Indonesia, Australia Coronavirus (MIACoV).
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Tozinameran - Standard dose|BIOLOGICAL: Tozinameran - fractional dose|BIOLOGICAL: Elasomeran - standard dose|BIOLOGICAL: Elasomeran - fractional dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Clinic Attendance for Medication Collection Among HIV Positive Individuals in Nepal
Status: COMPLETED
Conditions: HIV Infections|Antiretroviral Therapy|HIV Seropositivity
Interventions: BEHAVIORAL: Mobile phone reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Whole-body Vibration in Spastic Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Group 1 Experimental group|OTHER: Group 2 Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: 30 mg Paracetamol 3% (1 mL)|DRUG: 60 mg Paracetamol 3% (2 mL)|DRUG: 90 mg Paracetamol 3% (3 mL)|DRUG: Placebo, 0.9% saline solution|DRUG: NIMP: Chloroprocaine HCl 1% (10 mg/mL), solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comfort Associated With The Use Of Eyelid Cleansing Products Available For The Management Of Demodex Folliculorum
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Sensitive Eyes® Plus Saline Solution|OTHER: Oust™ Demodex® Wipes™|OTHER: I-LID N LASH PLUS® Eyelid Cleanser|OTHER: Blephadex Lid Wipes|OTHER: Eye Cleanse Lid Wipes|OTHER: Blephademodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Stress Testing on Peripheral Gene Expression Using Corus CAD (or ASGES) Diagnostic Test
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: CVT-301 Low Dose|DRUG: CVT-301 High Dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of a Psychosocial Intervention Program for Siblings of Children With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Control Group|BEHAVIORAL: Experimental Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma
Status: WITHDRAWN
Conditions: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)|Ewing Sarcoma of Bone|Extraosseous Ewing Sarcoma|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: DRUG: etoposide|DRUG: ifosfamide|RADIATION: intensity-modulated radiation therapy|DRUG: topotecan hydrochloride|DRUG: busulfan|DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: autologous bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Use Disorder in the Emergency Department: CTN 0069
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: OTHER: Standard Dissemination Practice|OTHER: Implementation Facilitation (IF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ASP8825 - Study in Patients With Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: ASP8825|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401)
Status: COMPLETED
Conditions: Lymphoma, B-Cell|Lymphoma, Large-Cell, Immunoblastic|Lymphoma, Non-Hodgkin
Interventions: DRUG: Autologous transplantation using rituxan/BEAM|DRUG: Autologous transplantation using Bexxar/BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Clinical Study of Endoscopic Ablation for Atrial Fibrillation (AF) in Patients That Have Failed Drugs
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Endoscopic Ablation System|DRUG: Standard Anti-arrhythmic Drug (AAD) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Broccoli sprout homogenate|DIETARY_SUPPLEMENT: alfalfa sprout homogenate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of SERT Inhibition on the Subjective Response to LSD in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine|DRUG: Lysergic Acid Diethylamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant PD-1 Monoclonal Antibody in Cisplatin-ineligible High Risk Upper Tract Urothelial Carcinoma
Status: COMPLETED
Conditions: Neoadjuvant Immunotherapy of Cisplatin-ineligible High Risk Upper Urinary Tract Urothelial Carcinoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Techniques for Perineal Skin Closure During Mediolateral Episiotomy Repair
Status: UNKNOWN
Conditions: Episiotomy
Interventions: PROCEDURE: subcuticular suturing|PROCEDURE: Surgical glue|PROCEDURE: adhesive steri-strip tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of p62/SQSTM1 as a Malignant Transformation Marker for Oral Potentially Malignant Disorders and a Prognostic Marker for Oral Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Oral Potentially Malignant Disorder|Oral Cancer|Malignant Disorder|p62/SQSTM1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p