pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Contact: Developing New Clinical Management Strategies
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: RECRUITING
Conditions: Neoplasms, Ovarian
Interventions: DRUG: MORAb-202|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin (PLD)|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer
Status: TERMINATED
Conditions: Newly Diagnosed Breast Cancer
Interventions: DIAGNOSTIC_TEST: Hybrid breast FDG PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Addition of Regional Analgesia to Reduce Postoperative Delirium in Patients Having Hip Fracture Surgery.
Status: TERMINATED
Conditions: Delirium|Hip Fracture
Interventions: PROCEDURE: Femoral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BIOmarker-guided Study to Evaluate the Efficacy and Safety of cemipLimab for advancEd Cutaneous T-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Mycosis Fungoides
Interventions: DRUG: Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study for the Pan-vascular Interventional Robotic System
Status: NOT_YET_RECRUITING
Conditions: Percutaneous Coronary Intervention|Pan-vascular Interventional Robotic System
Interventions: DEVICE: Pan-vascular interventional robotic system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-macular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Sub-macular injection of Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Network Connectivity and Inhibitory Control Under Atomoxetin Challenge- A Pharmacological 'Resting State' and 'Inhibiton Task' Study in Patients With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Atomoxetine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of TU2218 in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: TU2218 + Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Magnesium Sulfate on Motor and Somatosensory Evoked Potentials in Children Undergoing Scoliosis Surgery
Status: COMPLETED
Conditions: Scoliosis
Interventions: DRUG: Magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study of STT-5058, an Antibody That Binds ApoC3
Status: TERMINATED
Conditions: Hypertriglyceridemia
Interventions: DRUG: STT-5058|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing Individualized Strategies to Prevent Nausea and Vomiting
Status: WITHDRAWN
Conditions: Postoperative Nausea and Vomiting|Genetic Polymorphisms
Interventions: DRUG: Ondansetron|DRUG: Lorazepam|DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Drainless Donor Abdominal Site in Deep Inferior Epigastric Perforator (DIEP) Flap on Complications and Duration of Hospital Stay.
Status: NOT_YET_RECRUITING
Conditions: Breast Reconstruction
Interventions: PROCEDURE: DIEP flap surgery without drain|PROCEDURE: DIEP flap surgery with drains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LAU-7b in the Treatment of Cystic Fibrosis in Adults
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: LAU-7b|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test if Fremanezumab Reduces Headache in Participants With Posttraumatic Headache (PTH)
Status: COMPLETED
Conditions: Post-Traumatic Headache
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glycaemic Response to Oral Nutrition Support During Haemodialysis
Status: COMPLETED
Conditions: Diabetes|Chronic Kidney Disease|End Stage Renal Failure on Dialysis
Interventions: DIETARY_SUPPLEMENT: Nepro HP (Abbott Nutrition)|DIETARY_SUPPLEMENT: Fortisip compact protein 125 ml + Calogen 20ml (Nutricia)|DIETARY_SUPPLEMENT: Fortisip compact 125 ml (Nutricia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patterns of Neurocircuitry Activation In Severe Asthma
Status: COMPLETED
Conditions: Lung Diseases
Interventions: OTHER: functional Magnetic Resonance Imaging (research grade)|OTHER: Cognitive Function Testing (non-diagnostic)|OTHER: Asthma and Psychological Questionnaires (non-diagnostic)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: [18F]FluorThanatrace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sucrose Analgesia in Infants Undergoing Casting for Club Foot
Status: UNKNOWN
Conditions: Clubfoot
Interventions: DIETARY_SUPPLEMENT: sucrose solution|DIETARY_SUPPLEMENT: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine the Utility of FES-PET in the Prediction of Response to Fulvestrant in Women With Estrogen Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Fluoroestradiol (18F)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Education and the Prevention of Iron Depletion in Children 9 Months to 2 Years
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: OTHER: Healthy milk intake|OTHER: Standard nutrition counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Head Acupuncture After Mechanical Thrombectomy for Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acupuncture|Acute Ischemic Stroke|Mechanical Thrombectomy
Interventions: OTHER: Scalp Acupuncture|OTHER: The treatment recommended in the guidelines for acute ischemic stroke was administered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Impact of Fulticasone Furoate/Vilanterol vs. Tiotropium on Arterial Stiffness in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone furoate (FF, GW685698)/vilanterol (VI, GW642444) 100/25 mcg Novel Dry Powder Inhaler (NDPI)|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Multimodality Pain Management Protocol on Postoperative Neurosurgical Pain
Status: COMPLETED
Conditions: Pain|Postoperative Pain|Surgical Pain|Neurosurgical Pain
Interventions: OTHER: Pain Management Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Lactoferrin Supplementation on Urinary Tract Infections in Infants.
Status: COMPLETED
Conditions: Urinary Tract Infections in Children
Interventions: DIETARY_SUPPLEMENT: Bovine Lactoferrin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BMS-298585 Alone or in Combination With Pravastatin in Subjects With Mixed Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Muraglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Bone Marrow Concentrate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease|IBD
Interventions: DRUG: Brazikumab low dose|DRUG: Brazikumab high dose|DRUG: Humira®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Snacks on Appetite Control
Status: COMPLETED
Conditions: Healthy Canadians|Appetite Control
Interventions: OTHER: gluten-free high protein snack #1|OTHER: gluten-free snack with similar energy density but 1/2 the protein as snack #1|OTHER: non-caloric control|OTHER: gluten-free high protein and high fibre snack #2|OTHER: gluten-free snack with similar energy density, but less protein and fibre than snack #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Cognitively-Based Compassion Training and Mindfulness Attention Training Program
Status: COMPLETED
Conditions: Behavioral Resilience|Biological Resilience
Interventions: BEHAVIORAL: Cognitively-Based Compassion Training (CBCT)|BEHAVIORAL: Mindfulness training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Value of Endocervical and Endometrial Lidocaine Flushing Before Office Hystroscopy
Status: UNKNOWN
Conditions: Pain During Hystroscopy
Interventions: DRUG: Lidocaine|PROCEDURE: Office hystroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study Between Two Different Approaches of Brachial Plexus Block: Supraclavicular Approach and Retroclavicular Approach
Status: COMPLETED
Conditions: Brachial Plexus Block
Interventions: PROCEDURE: supraclavicular brachial plexus block|PROCEDURE: Retroclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Dolutegravir to Obesity and Cardiovascular Disease
Status: COMPLETED
Conditions: HIV-1-infection|Antiviral Drug Adverse Reaction|Vascular Diseases|Cardiovascular Abnormalities|Abnormality of Adipose Tissue|Body Weight Changes|Body Fat Disorder|HIV-Associated Lipodystrophy Syndrome
Interventions: DRUG: Dolutegravir 50 MG|DRUG: Antiretroviral/Anti HIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus
Status: RECRUITING
Conditions: Tinnitus|Epilepsy, Temporal Lobe
Interventions: OTHER: acoustics tests, Questionaries,|RADIATION: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of RGLS4326 in Patients With Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney Disease, Autosomal Dominant
Interventions: DRUG: RGLS4326
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)
Status: TERMINATED
Conditions: Contraception
Interventions: DRUG: ENG-E2 125 μg/300 μg vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Alkalinized Lidocaine in the Endotracheal Tube Cuff on the Incidence of Coughing During Emergence
Status: COMPLETED
Conditions: Cough|Anesthesia
Interventions: DRUG: Alkalinized lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma
Interventions: RADIATION: Radiation Therapy|DRUG: Dexamethasone|DRUG: Etoposide phosphate|DRUG: Ifosfamide|DRUG: Mesna|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Postoperative Delirium Inflammasome Activation Inhibition
Status: UNKNOWN
Conditions: Patients Under Hip, Femur, Spine Operation
Interventions: DRUG: Dexmedetomidine IV infusion|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Mind-body Educational Program to Enhance Resiliency and Reduce Burnout in First Year Residents
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Stress Management and Resiliency Training for Residents (SMART-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomised Multicenter Study Comparing the Sliding Hip Screw and the Intertan Nail in Trochanteric and Subtrochanteric Femoral Fractures
Status: COMPLETED
Conditions: Trochanteric and Subtrochanteric Hip Fractures|Treatment With a New Nail or a Sliding Hip Screw
Interventions: PROCEDURE: Intertan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Training on Shoulder Muscles Strength Post Mastectomy
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: PROCEDURE: Biofeedback device and other group control group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Gastric pH Control With High Dose Intravenous or Oral Esomeprazole
Status: TERMINATED
Conditions: Gastrointestinal Hemorrhage
Interventions: DRUG: Intravenous bolus injection of esomeprazole|DRUG: Oral esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Prehabilitation Management Pathway and Network Platform Construction
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Prehabilitation
Interventions: BEHAVIORAL: Internet + wearble device multimodal prehabilitation|BEHAVIORAL: traditional multimodal prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial Evaluating the Efficacy and Safety of the Sublingual Sufentanil Tablet 30 mcg for Post-Operative Pain After Abdominal Surgery
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Sufentanil Tablet 30 mcg|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digihaler in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: COMBINATION_PRODUCT: Albuterol eMDPI DS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An RSA and DEXA Study on Migration of Proximal Interphalangeal (PIP) Joint Prostheses of the Hand
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Avanta (PIP joint implant with a titanium porous coating)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transfusion in Sickle Cell Disease: Screening of Sickle Cell Disease Trait in Blood Donors
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Trait
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intensive Therapies to Improve Manipulation in Young Children With Hemiparesis
Status: COMPLETED
Conditions: Infantile Hemiplegia|Constraint Induced Movement Therapy|Family|Bimanual Intensive Therapy
Interventions: PROCEDURE: INFANT CIMT/BIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of EXG001-307 in Patients With Spinal Muscular Atrophy Type I
Status: COMPLETED
Conditions: Type I Spinal Muscular Atrophy
Interventions: DRUG: EXG001-307 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Safety, Toleration And Efficacy of PF00610355 In Chronic Obstructive Pulmonary Disease (COPD) Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases|Lung Diseases, Obstructive
Interventions: DRUG: PF-00610355|DRUG: PF - 00610355|DRUG: PF- 00610355|DRUG: Placebo|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Face to Face or Digitally Delivered First-line Osteoarthritis Treatment?
Status: COMPLETED
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: OTHER: Three months of digitally delivered osteoarthritis treatment|OTHER: Three months of face-to-face delivered osteoarthritis treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vitamin D Supplementation on Muscular Strength, Musculoskeletal Pain and Headache
Status: COMPLETED
Conditions: Vitamin Deficiency
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Somatosensory Intensive Intervention on Motor Performance in Children With Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Unilateral Cerebral Palsy
Interventions: OTHER: Somatosensory intensive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for Cesarean
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Pregabalin 100Mg Oral Cap|DRUG: Hydrocortisone|DRUG: Acetaminophen|OTHER: oral fluids|DRUG: Caffeine|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sub-thalamic Nucleus Stimulation in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: New targeting procedure without electrophysiology|PROCEDURE: Classical neurosurgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMA
Status: WITHDRAWN
Conditions: Neuroblastoma
Interventions: DRUG: cyclophosphamide|DRUG: Fludarabine|GENETIC: GINAKIT Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Breast Tomosynthesis Mammography and Conventional Breast Imaging in the Characterization of Breast Masses
Status: COMPLETED
Conditions: Fibrocystic Disease of Breast|Breast Cancer
Interventions: DEVICE: Digital Breast Tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Oral p38 Inhibitor Investigating Safety, Efficacy, And PK In Subjects With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: placebo|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804|DRUG: PH-797804
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Chest Wall Vibration in COPD Rehabilitation
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Cycle ergometer training|OTHER: Airway clearance program|DEVICE: Vibration therapy|DEVICE: Sham vibration therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: 500mg IV GSK1322322/placebo|DRUG: 1000mg oral GSK1322322/placebo|DRUG: 1000mg IV GSK1322322/placebo|DRUG: 1500mg oral GSK1322322/placebo dose|DRUG: 1500mg IV GSK1322322/placebo|DRUG: 2000mg IV GSK1322322J/placebo|DRUG: 3000mg IV GSK1322322J/placebo|DRUG: 1000mg IV GSK1322322J/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for MS
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Exposure of Simulated Hypoxia on Pulmonary Artery Pressure and Right Heart Function (Echo)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DEVICE: Simulated Altitude (FiO2: 15.1%)|DEVICE: Shamed Hypoxia (FiO2: 20.9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant Chemotherapy
Status: COMPLETED
Conditions: Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Estrogen Receptor Negative|HER2/Neu Negative|Inflammatory Breast Carcinoma|Progesterone Receptor Negative|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Stage IIB Breast Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIC Breast Cancer AJCC v7|Triple-Negative Breast Carcinoma
Interventions: DRUG: Atorvastatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas
Status: UNKNOWN
Conditions: Glioblastoma Multiforme|Astrocytoma Anaplastic Foci
Interventions: DRUG: MAB-425 radiolabeled with I-125
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of the Use of Siltuximab (SYLVANT) in Patients Diagnosed With COVID-19 Infection Who Have Developed Serious Respiratory Complications
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome (ARDS) Secondary to SARS-COV-2 Infection
Interventions: OTHER
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Can Changes in Velocity Time Integral Serve as a Sensitive Indicator for Monitoring Changes in Stroke Volume ?
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: OTHER: Passive Leg Raising (PLR) test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Furcation Treatment With L-PRF and aPDT
Status: COMPLETED
Conditions: Furcation Defects
Interventions: PROCEDURE: L-PRF with aPDT|PROCEDURE: L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of New Human Models of Non-histaminergic Itch and Their Interaction With the TRPM8 Receptor
Status: COMPLETED
Conditions: Itch
Interventions: DRUG: Doxepin Topical|DRUG: Papain|DRUG: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of a Cosmetic Lotion in the Treatment of Alopecia Areata in Males and Females
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: OTHER: MEXIS/M6S Patent - lotion against alopecia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive or Open Surgery for Lung Cancer: Pain, Quality of Life and Economics.
Status: COMPLETED
Conditions: Nonsmall Cell Lung Cancer Cellular Diagnosis
Interventions: PROCEDURE: Anterolateral thoracotomy|PROCEDURE: Posterolateral thoracotomy|PROCEDURE: VATS|PROCEDURE: Anterolateral Thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: 17-AAG in Treating Patients With Relapsed or Refractory Anaplastic Large Cell Lymphoma, Mantle Cell Lymphoma, or Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: DRUG: tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild TBI Assessment & Rehabilitation
Status: RECRUITING
Conditions: Brain Injuries, Traumatic
Interventions: BEHAVIORAL: Goal-Oriented Attentional Self-Regulation (GOALS)|OTHER: Brain Health Education (BHE)|DEVICE: fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).
Status: COMPLETED
Conditions: Central Diabetes Insipidus
Interventions: DRUG: Desmopressin Oral Melt|DRUG: Desmopressin intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers
Status: RECRUITING
Conditions: Localized Prostate Carcinoma|Locally Advanced Cervical Carcinoma|Locally Advanced Rectal Carcinoma|Malignant Solid Neoplasm|Recurrent Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage IB Cervical Cancer FIGO 2018|Stage IB2 Cervical Cancer FIGO 2018|Stage II Prostate Cancer AJCC v8|Stage II Rectal Cancer AJCC v8|Stage IIA Cervical Cancer FIGO 2018|Stage IIB Cervical Cancer FIGO 2018|Stage III Prostate Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IIIA Cervical Cancer FIGO 2018|Stage IIIB Cervical Cancer FIGO 2018|Stage IIIC Cervical Cancer FIGO 2018|Stage IVA Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Informational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BEHAVIORAL: Short-Term Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Differential Thrombogenesis Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) Mediated by High-Density Lipoprotein (HDL).
Status: NOT_YET_RECRUITING
Conditions: Lipid Metabolism Disorders
Interventions: DRUG: EPA|DRUG: DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Characterize The Modulatory Effects Of Dopamine D2/D3 Receptor Agonist And Antagonist Drugs On Compulsive Behaviors
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Pramipexole, Amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Buprenorphine Sublingual Spray for the Treatment of Moderate to Severe Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IPACK Block Versus Adductor Canal Block in High Tibeal Osteotomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Infiltration of local anaesthetic between popliteal artery and posterior knee capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Effectiveness and Safety Study for Levofloxacin in Chronic Prostatitis
Status: COMPLETED
Conditions: Prostatitis
Interventions: DRUG: levofloxacin|DRUG: levofloxacin|DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically
Status: COMPLETED
Conditions: Arterial Embolization|Other Surgical Procedures|Obesity
Interventions: DEVICE: BeadBlock 300 - 500 Micron|PROCEDURE: Left Gastric Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study on the Lipid-lowering Effect of Plant Sterols and Fish Oil
Status: COMPLETED
Conditions: Healthy|Mildly Elevated Cholesterol Levels
Interventions: DIETARY_SUPPLEMENT: Plant sterols and fish oil|DIETARY_SUPPLEMENT: Plant sterols|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for Treatment of Acute Complicated Type B Aortic Dissection
Status: COMPLETED
Conditions: Type B Aortic Dissection
Interventions: DEVICE: GORE TAG® Thoracic Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Registration of mOrbidity and Mortality, individUal radioSensitivity and Radiation Technique (PROUST)
Status: NOT_YET_RECRUITING
Conditions: Radiotherapy
Interventions: OTHER: Morbidity Mortality Review (MMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antibody-mediated NMDA Receptor Encephalitis: Symptoms, Biomarkers, and Mechanisms of the Prolonged Recovery Stage
Status: RECRUITING
Conditions: Anti-NMDA Receptor Encephalitis
Interventions: BEHAVIORAL: Remote cognitive rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adult Safety Study of 2009/2010 Seasonal Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Seasonal influenza vaccine (split virion, inactivated, prepared in Vero Cell cultures)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Expiratory Muscle Training on Cough Efficacy in Children and Adolescents With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: expiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study to Assess Visual Function in Subset of Patients Who Have Previously Participated in the TG-MV-006 and TG-MV-007 Ocriplasmin Studies
Status: COMPLETED
Conditions: Symptomatic Vitreomacular Adhesion
Interventions: DRUG: ocriplasmin|DRUG: placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Ductal Lavage in Women at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: fluorescence in situ hybridization|GENETIC: polymerase chain reaction|GENETIC: proteomic profiling|OTHER: cytology specimen collection procedure|OTHER: immunohistochemistry staining method|PROCEDURE: breast duct lavage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of the Intermediate Vaginal Microbiota With Vaginal Lactobacillus Casei Rhamnosus to Improve Pregnancy Outcome
Status: COMPLETED
Conditions: Lactobacillus Infection
Interventions: DRUG: Lactobacillus casei rhamnosus (Lcr 35 regenerans)|OTHER: NO Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TISLELIZUMAB Combined With Anlotinib and Chemotherapy(XELOX) in the Treatment of Advanced Gastric Carcinoma
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: BGB-A317|DRUG: Anlotinib|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Beef on Muscle Fatigue in Older Adults
Status: RECRUITING
Conditions: Muscle Weakness|Muscle; Fatigue, Heart|Older Adults
Interventions: OTHER: Beef Diet|OTHER: Vegetarian Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DIAGNOSTIC_TEST: VCA-IgA, EBNA1-IgA, and EBV-DNA|DIAGNOSTIC_TEST: EBV C Promoter Methylation Detection in nasopharyngeal swab samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Concurrent Cisplatin Chemoradiation With or Without Capecitabine as Adjuvant Chemotherapy in Local Advanced High Risk Nasopharyngeal Carcinoma: Randomized Control Clinical Trial
Status: COMPLETED
Conditions: Local Advanced High Risk Nasopharyngeal Carcinoma
Interventions: DRUG: IMRT combine with cisplatin concurrent chemotherapy|DRUG: IMRT combine with cisplatin concurrent chemotherapy plus capecitabine adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS and Opioid Use After Cesarean Delivery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cesarean Section Complications|Opioid Use
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Faecal Incontinence With a Novel Anal Device: a Cost-effectiveness Trial
Status: COMPLETED
Conditions: Faecal Incontinence
Interventions: DEVICE: Navina anal insert|OTHER: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tolerability, Safety and Pharmacokinetics of Four Formulations of Ketorolac Tromethamine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Ketorolac Tromethamine with 4% Lidocaine hydrochloride (HCl)|DRUG: Ketorolac Tromethamine with 5% Lidocaine HCl|DRUG: 30 mg Ketorolac Tromethamine with 6% Lidocaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Cognitive Training on Cognitive Function in Elderly Diabetes Patients in the Community
Status: NOT_YET_RECRUITING
Conditions: Cognition|Diabetes Mellitus, Type 2|Aging
Interventions: DEVICE: adaptive cognitive training|DEVICE: placebo cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Apalutamide in Combination With 89Sr as Neoadjuvant Therapy in Prostate Cancer With ≤10 Bone Metastases
Status: RECRUITING
Conditions: Prostate Cancer With ≤10 Bone Metastases
Interventions: DRUG: Apalutamide|DRUG: 89Sr|DRUG: Luteinizing Hormone-Releasing Hormone Analog
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Assess the Efficacy and Safety of AKB-9778 in Subjects With Macular Edema Due to RVO
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: AKB-9778
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial
Status: RECRUITING
Conditions: Coronary Disease
Interventions: DEVICE: computed tomography perfusion guided treatment|DEVICE: Fractional flow reserve guided treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of the HELPeN Program on Social Isolation in Community-dwelling Elders (HELPeN)
Status: RECRUITING
Conditions: Loneliness|Isolation, Social
Interventions: OTHER: Help eNursing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ripretinib Combined With Surgery in Advanced GIST That Have Failed Imatinib Therapy: A Multicenter,Observational Study
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumor(GIST)
Interventions: PROCEDURE: Resection surgery of gastrointestinal stromal tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 1)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: PegIFN/RBV|DRUG: BI 201335|DRUG: BI 201335|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Heliox in Experimental Upper Airway Obstruction
Status: COMPLETED
Conditions: Airway Obstruction|Dyspnea
Interventions: DRUG: HELIOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on HD Hf-tRNS Over Bilateral DLPFC for Treating Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Psychotic Symptoms|Neurocognitive Dysfunction|Insight Impaired|Quality of Life|Psychosocial Impairment|Autonomic Imbalance|EEG With Abnormally Slow Frequencies
Interventions: DEVICE: HD hf-tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Different Capsules, APL-101 and PLB-1001 Capsules, in Healthy Chinese and Caucasian Participants
Status: UNKNOWN
Conditions: Bioequivalence
Interventions: DRUG: APL-101|DRUG: PLB-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Veterans Intensive Personalized Treatment in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Telephone-Delivered BI|BEHAVIORAL: Telephone-Delivered BEI|OTHER: Telephone-Delivered API
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nilotinib in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Cohort 1:Nilotinib Oral Capsules (150mg or 300mg)|DRUG: Cohort 2: Nilotinib Oral Capsules (dose to be determined from Cohort 1)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Infusion of Anti-MART-1 F5 TCR-Gene-Engineered Lymphocytes
Status: COMPLETED
Conditions: Melanoma|Skin Cancer
Interventions: BIOLOGICAL: autologous anti-MART-1 F5 T-cell receptor|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Aldesleukin|BIOLOGICAL: autologous anti-MART-1 F5 T-cell receptor gene-engineered tumor infiltrating lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromuscular Calf Stimulation and Intermittent Pneumatic Compression on Lower Limb Venous Hemodynamics
Status: COMPLETED
Conditions: Intermittent Pneumatic Compression
Interventions: DEVICE: Neuromuscular stimulation, followed by intermittent pneumatic compression|DEVICE: Intermittent pneumatic compression, followed by neuromuscular stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Millet Products Study - Investigation of Glycemic Index and Satiety
Status: COMPLETED
Conditions: Hyperglycemia|Lack of Satiety
Interventions: OTHER: Commercial white bread|OTHER: Corn based products (porridge etc.)|OTHER: Millet based products (porridge etc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Saffron Supplementation on Macular Cone-mediated Function in Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Saffron|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions
Status: TERMINATED
Conditions: Pancreatic Cysts|Pancreatic Mucinous-Cystic Neoplasm|Intraductal Papillary Mucinous Neoplasm|Solid Pseudopapillary Tumour of the Pancreas|Cystadenocarcinoma|Serous Cystadenoma
Interventions: PROCEDURE: Endoscopic ultrasound guided needle based confocal endomicroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p