pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Promotion of Active Lifestyle in Thromboembolism Patients
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Thromboembolism
Interventions: OTHER: Physical Activity Promotion|OTHER: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Augmented and Virtual Reality Gait Training on Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Augmented and Virtual Reality Gait and balanceTraining|OTHER: Conventional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy of Toxic Optic Neuropathy Via Combination of Stem Cells With Electromagnetic Stimulation
Status: COMPLETED
Conditions: Methanol Poisoning|Toxic Optic Neuropathy|Stem Cell Tyrosine Kinase 1 Y842X|Magnetic Field Exposure
Interventions: BIOLOGICAL: Wharton jelly derived mesenchymal stem cell|DEVICE: Repetitive electromagnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryolipolysis and Subcision for Treatment of Cellulite
Status: COMPLETED
Conditions: Cellulite
Interventions: DEVICE: cryolipolysis|PROCEDURE: Subcision|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic RT Versus Prophylactic Extended-field RT in Patients With Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: RADIATION: Prophylactic extended-field Irradiation|RADIATION: Pelvic irradiation|RADIATION: Intracavitary brachytherapy|DRUG: Concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia
Status: UNKNOWN
Conditions: Impaired Cognition|Schizophrenia
Interventions: DRUG: Donepezil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts
Status: COMPLETED
Conditions: Genital Warts
Interventions: DRUG: GS-9191 ointment|DRUG: GS-9191|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Sugammadex in Outpatient Urological Procedures
Status: COMPLETED
Conditions: Malignant Neoplasms of Urinary Tract|Bladder Cancer
Interventions: DRUG: Rocuronium|DRUG: Sugammadex|DRUG: Neostigmine|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Lip Repositioning for the Treatment of Excess Gingival Display With and Without Pretreatment With Botox
Status: UNKNOWN
Conditions: Gingival Overgrowth
Interventions: DRUG: Botox Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS, AirCurve 10CS): Predictive Factors of Poor Compliance (FACE)
Status: WITHDRAWN
Conditions: Central Sleep Apnea|Heart Failure
Interventions: OTHER: telemonitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SkinTE® in the Treatment of Venous Leg Wounds
Status: COMPLETED
Conditions: Venous Leg Ulcer|Venous Stasis|Venous Stasis Ulcer
Interventions: OTHER: Human Autologous Homologous Skin Construct|OTHER: Additional Outer Dressing Application|OTHER: Fibracol Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: DEVICE: 50% cortical/50% cancellous FDBA|DEVICE: 100% cortical FDBA|DEVICE: 100% cancellous FDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Exploratory Study to Evaluate the Safety and Immunogenicity of Omicron Variant Bivalent Vaccine V-01-B5
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Pandemic
Interventions: BIOLOGICAL: V-01/V-01-B5|BIOLOGICAL: V-01-351/V-01-B5|BIOLOGICAL: V-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: L-dopa/Carbidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Alzheimer's and Dementia With the Metabolism, Infections, Nutrition, Drug Elimination (MIND) Protocol
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia
Interventions: OTHER: A mix of natural treatments and medications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversal of Hepatic Impairment in Patients With Hepatitis C Virus (HCV) and Early Decompensation of Cirrhosis
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Simeprivir (SMV)|DRUG: Sofosbuvir (SOF)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 131Iodine-Tenatumomab Treatment in Tenascin-C Positive Cancer Patients
Status: TERMINATED
Conditions: Breast Neoplasm|Head and Neck Neoplasm|Skin Neoplasm|Respiratory Tract Neoplasm|Urogenital Neoplasm|Digestive System Neoplasm|Pancreatic Neoplasm|Connective and Soft Tissue Neoplasm|Lymphoma, Non-Hodgkin
Interventions: COMBINATION_PRODUCT: 131I-Tenatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)
Status: COMPLETED
Conditions: Kaposi Sarcoma|HIV Infections
Interventions: DRUG: Tc99m-tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial on the Effect of Simulation-based Diagnostic Abdominal Ultrasound Training
Status: COMPLETED
Conditions: Pathology
Interventions: OTHER: Simulation-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases
Status: UNKNOWN
Conditions: Cancer|Cancer Cachexia|Inflammation|Muscular Atrophy
Interventions: OTHER: WB-EMS (Sham-intervention)|OTHER: WB-EMS|OTHER: Free WB-EMS|OTHER: Flexi band resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Predictive Effects of Mulligan Treatment in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Orthopedic Disorder of Spine|Placebo Effect|Disability Physical
Interventions: OTHER: Mobilization With Movement Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Safety Study Evaluating the Use of Dexmedetomidine in Pediatric Subjects Undergoing Procedure-Type Sedation
Status: COMPLETED
Conditions: Ultrasound|CT Scans|MRIs
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.
Status: RECRUITING
Conditions: Polyneuropathy|Amyloidosis
Interventions: DIAGNOSTIC_TEST: ECG + echocardiography|OTHER: Answering questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: IMPULSE - StIMulation of Brain Plasticity to Improve Upper Limb Recovery After StrokE
Status: TERMINATED
Conditions: Chronic Stroke|Subacute Stroke
Interventions: DRUG: Cerebrolysin|DEVICE: non-invasive brain stimulation|DRUG: Placebo|DEVICE: sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Versus Oxaliplatin as Addition to S-1 for Stage II / III Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gonadotropin-Releasing Hormone Agonist for the Preservation of Ovarian Function During Chemotherapy in Premenopausal Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: goserelin|DRUG: standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Study of 42037788 (Referred to as CNTO 0007) Compared With Placebo in Patients Who Have Experienced Ischemic Cerebral Infarction (Also Known as Stroke)
Status: COMPLETED
Conditions: Stroke|Ischemia|Infarction
Interventions: DRUG: CNTO 0007 or placebo (Stage A)|DRUG: CNTO 0007 or placebo (Stage B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer
Status: TERMINATED
Conditions: Metastatic Cancer|Metastatic Melanoma|Renal Cancer
Interventions: BIOLOGICAL: Anti-VEGFR2 CAR CD8 plus PBL|DRUG: Cyclophosphamide|BIOLOGICAL: Aldesleukin|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research of Zoledronic Acid and Aromatase Inhibitors as Adjuvant Therapy to Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Zoledronic Acid and Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Cerclage in Twin Pregnancies at Imminent Risk of Preterm Birth: an Open-Label Randomised Controlled Trial
Status: UNKNOWN
Conditions: Preterm Birth|Twin Pregnancy With Antenatal Problem|Twin to Twin Transfusion Syndrome
Interventions: PROCEDURE: Insertion of cervical cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Supplementation in CKD - Vascular Function, Structure and Immune Regulation
Status: COMPLETED
Conditions: Atherosclerosis|Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Oral, Direct Factor Xa Inhibitor, BAY59-7939, for Prophylaxis Against Venous Thromboembolism After Total Knee Replacement: a Dose-Ranging Study
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban, (BAY59-7939)|DRUG: Rivaroxaban, (BAY59-7939)|DRUG: Rivaroxaban, (BAY59-7939)|DRUG: Enoxaparine|DRUG: Enoxaparine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effects of Potatoes on Blood Pressure in Persons With and Without Type 2 Diabetes Who Follow the DASH Diet for 6 Weeks
Status: COMPLETED
Conditions: Type 2 Diabetes|Blood Pressure
Interventions: OTHER: DASH-FP|OTHER: DASH-NFP|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Fecal Microbiota Transplantation (FMT) for Severe Acute Pancreatitis(SAP)
Status: UNKNOWN
Conditions: Acute Pancreatitis|Intestinal Bacteria Flora Disturbance|Intestinal Dysfunction|Fecal Microbiota Transplantation
Interventions: OTHER: Fecal Microbiota Transplantation|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE)
Status: COMPLETED
Conditions: Brain Metastases
Interventions: DRUG: 18F fluciclovine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D Supplementation in Adult Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Video Laryngoscopy Versus Direct Laryngoscopy for Orotracheal Intubation Among Adults in Emergency Department
Status: NOT_YET_RECRUITING
Conditions: To Compare Success Rate of Video Laryngoscopy vs Direct Laryngoscopy
Interventions: DEVICE: Oro Tracheal Intubation by DL|DEVICE: Oro Tracheal Intubation by VL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Various Types of the Renin-angiotensin-aldosterone System Blockade on Proteinuria
Status: COMPLETED
Conditions: Chronic Kidney Disease|Proteinuria
Interventions: DRUG: aliskiren, eplerenon, telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Out of Hospital Cardiac Arrest: Trial Assessing the Survival Impact of Phone Advice
Status: UNKNOWN
Conditions: Out of Hospital Cardiac Arrest
Interventions: OTHER: Protocol phone advice|OTHER: Usual phone advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mills Manipulation and Nirschel Exercises in Patients With Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: OTHER: Mills manipulation in addition to myofasical release therapy|OTHER: Nirschl exercises in addition to myofascial release therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: sEphB4-HSA With RT+Chemo or Cetux in Patients With Intermediate to High Risk LAHNSCC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: sEphB4-HSA with chemotherapy|DRUG: Cetuximab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With Lenvatinib and Sintilimab for Hepatocellular Carcinoma With PVTT
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Liver Neoplasms|Sintilimab|Portal Vein Tumor Thrombus
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact (PRCTS2S)
Status: COMPLETED
Conditions: Premature Baby 33 to 36 Weeks|Mother-Infant Interaction|Oxidative Stress
Interventions: BEHAVIORAL: Skin-to-skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Safety, Pharmacokinetics and Pharmacodynamics of RO5508887 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Placebo|DRUG: RO5508887|DRUG: RO5508887
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Acceptance and Commitment Therapy in Patients With Advanced Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Advanced Cancer
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bortezomib in Treating Young Patients With Refractory or Recurrent Leukemia
Status: COMPLETED
Conditions: Blastic Phase Chronic Myelogenous Leukemia|Childhood Acute Promyelocytic Leukemia (M3)|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: DRUG: bortezomib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Broccoli Sprout Extract in Treating Women Who Have Had a Mammogram and Breast Biopsy
Status: COMPLETED
Conditions: Breast Cancer|Precancerous Condition
Interventions: DIETARY_SUPPLEMENT: broccoli sprout extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids
Status: ACTIVE_NOT_RECRUITING
Conditions: Allogeneic Disease|GVH - Graft Versus Host Reaction|GVHD, Acute|Stem Cell Transplant Complications
Interventions: DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
Status: RECRUITING
Conditions: Suicidal Ideation|Suicide Attempt|Self Harm
Interventions: DEVICE: Jaspr App + JAH|BEHAVIORAL: ETAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Administration of L.Plantarum WCFS1, L.Plantarum CIP104448, L.Plantarum CIP104450 on Small Intestinal Mucosa
Status: COMPLETED
Conditions: Gastro Intestinal Infection
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CD45RA Depleted DLI After TCRα/β Depleted Haploidentical HCT
Status: RECRUITING
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: CD45RA depleted donor lymphocyte infusion (DLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: YH12852 IR 0.05mg|DRUG: YH12852 IR 0.1mg|DRUG: YH12852 IR 0.3mg|DRUG: YH12852 IR 0.5mg|DRUG: YH12852 IR 1mg|DRUG: YH12852 IR 2mg|DRUG: YH12852 IR 3mg|DRUG: YH12852 DR1 0.5mg|DRUG: YH12852 DR1 1mg|DRUG: YH12852 DR1 2mg|DRUG: YH12852 DR1 4mg|DRUG: YH12852 DR2 8mg|DRUG: Prucalopride 2mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Synergistic Effect of Combination Therapy With Cilostazol and Probucol on Plaque Stabilization and Lesion Regression: Serial Intravascular Ultrasound and Virtual Histology Study(SECURE Study)
Status: COMPLETED
Conditions: Therapy
Interventions: DRUG: Cilostazol, Probucol / placebo of probucol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: GSK3196165 Dose 1|DRUG: GSK3196165 Dose 2|DRUG: GSK3196165 Dose 3|DRUG: Methotrexate|DRUG: Placebo|DRUG: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)
Status: COMPLETED
Conditions: Mood Disorder|Substance-Related Disorders|Amphetamine-Related Disorders
Interventions: DRUG: 3,4-Methylenedioxymethamphetamine|DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase IIIb Study to Evaluate the Effectiveness and Safety of Atazanavir/Ritonavir as Single Enhanced Protease Inhibitor Therapy in Human Immunodeficiency Virus (HIV)-Infected Subjects Evidencing Virologic Suppression
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infections
Interventions: DRUG: Atazanavir + Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of ABBV-951 in Subjects With Parkinson's Disease (PD)
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: ABBV-951
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: CCND1 Positive|CCND2 Positive|CCND3 Positive|CD20 Positive|Mantle Cell Lymphoma|Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit and Tolerability of IQP-AE-103 in Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: IQP-AE-103 (330mg)|DIETARY_SUPPLEMENT: IQP-AE-103 (165mg)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalation First Time in Human PK Study
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: 100 mg GSK investigational drug|DRUG: 200 mg GSK investigational drug|DRUG: 400 mg GSK investigational drug|DRUG: 800 mg GSK investigational drug|DRUG: 2000 mg GSK investigational drug|DRUG: 1500 mg GSK investigational drug|DRUG: 800mg fed GSK investigational drug|DRUG: 3000mg GSK investigational drug|DRUG: 4000mg GSK investigational drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunization With Autologous Dendritic Cells and Tumor Lysates in Melanoma Patients
Status: COMPLETED
Conditions: Stage III Malignant Melanoma of Skin AJCC V6|Stage IV Malignant Melanoma of Skin
Interventions: BIOLOGICAL: TAPCells vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Donor-Specific Tolerance in Renal Allograft Recipients (Living Donor) With TAIZ-Monocytes
Status: UNKNOWN
Conditions: Renal Transplantation
Interventions: DRUG: TAIZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. EMCOOLS Flex.Pads (iCOOL 2)
Status: UNKNOWN
Conditions: Ischemic Stroke|Hemorrhagic Stroke
Interventions: DRUG: Cold crystalloid infusions, 0.9%NaCl or Ringer's solution|DEVICE: EMCOOLS Flex.Pads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE With Lenvatinib Versus Lenvatinib Alone in in First-line Treatment of Advanced HCC
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NBTXR3 and Radiation Therapy in Treating Patients With Locally Advanced SCC of the Oral Cavity or Oropharynx
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DEVICE: NBTXR3 activated by IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Bifidobacterium V9(Kex02)Improving the Efficacy of Carilizumab Combined With Platinum in Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: V9|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain
Status: COMPLETED
Conditions: Melanoma and Brain Metastases
Interventions: DRUG: GSK2118436
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Pharmacogenetics Plus Drug Combination Guided Initial Tacrolimus Dosage in Renal Transplant Recipients
Status: UNKNOWN
Conditions: Renal Transplantation
Interventions: OTHER: drug (tacrolimus and SchE) and genetics|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex Infections
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection
Interventions: DRUG: Interferon Gamma for Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Outcomes for One-stage and Two-stage Brachial Basilic Arteriovenous Fistulas
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Failure|Hemodialysis Access Failure|Arterio-venous Fistula
Interventions: PROCEDURE: One stage approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does COVİD-19 m-RNA Vaccine Affect Fertility and Over Reserve ?
Status: COMPLETED
Conditions: COVID-19 Virus Infection|Ovarian Function Insufficiency|Fertility Disorders|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: sars cov 2 biontec vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina
Status: SUSPENDED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: veliflapon (DG-031)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Inspiratory Muscles Strength and Endurance Evolution on Difficult to Wean Patients in Intensive Care Unit
Status: COMPLETED
Conditions: Weaning From Mechanical Ventilation
Interventions: DIAGNOSTIC_TEST: Difficult to wean patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Treatment With Montelukast Improve Symptoms of Atopic Dermatitis in Children?
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Pediatric Rheumatology Diagnostic Decision Support in Clinical Use
Status: UNKNOWN
Conditions: Pediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)
Interventions: OTHER: Use of decision support tool|OTHER: Use of UpToDate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin's Lymphoma|Hodgkin's Disease|Myelogenous Leukemia|Lymphoblastic Leukemia
Interventions: DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: G-CSF|DRUG: Antithymocyte globulin|DRUG: Thymoglobulin|DRUG: Fludarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine-benazepril 10 mg-20 mg capsules|DRUG: Lotrel® 10 mg-20 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: PROCEDURE: Ultrasound guided erector spinae plane block|PROCEDURE: Intercostal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Status: RECRUITING
Conditions: Primary T-cell Immunodeficiency Disorders|Common Variable Immunodeficiency|Immune System Diseases|Autoimmune Lymphoproliferative|Lymphoproliferative Disorders
Interventions: DRUG: Immunosuppression Only Conditioning -Closed with amendment L|DRUG: Reduced Intensity Conditioning|DRUG: Myeloablative Conditioning-Closed with amendment L|DRUG: GVHD Prophylaxis|PROCEDURE: Allo BMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderators and Mediators of Perceptual Learning
Status: RECRUITING
Conditions: Cognitive Change
Interventions: BEHAVIORAL: C1 - Standard Perceptual Learning (SPL)|BEHAVIORAL: C2 - Long Training (LT)|BEHAVIORAL: C3 - Short Staircases (SS)|BEHAVIORAL: C4 - Mixed Difficulty (MD)|BEHAVIORAL: C5 - Noise Training (NT)|BEHAVIORAL: C6 - Training with Flankers (TWF)|BEHAVIORAL: C7 - Parafoveal Training (PT)|BEHAVIORAL: C8 - Stimulus Variety (SV)|BEHAVIORAL: C8a - Complex Features (CF)|BEHAVIORAL: C9 - Exogenous Attention Training (ExAT)|BEHAVIORAL: C10 - Endogenous Attention Training (EnAT)|BEHAVIORAL: C11 - Multisensory Facilitation (MF)|BEHAVIORAL: No Contact Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natesto Testosterone Nasal Gel for Hypogonadal Men
Status: WITHDRAWN
Conditions: Erectile Dysfunction|Sexual Dysfunction
Interventions: DRUG: Natesto Nasal Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Anti-ageing Supplement on Oxidative Stress
Status: COMPLETED
Conditions: Healthy Volunteers|Age Group: 60-70|Overweight
Interventions: DIETARY_SUPPLEMENT: ProManna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Status: RECRUITING
Conditions: Excessive Sleepiness|Shift-work Disorder
Interventions: DRUG: Solriamfetol 150 mg|DRUG: Solriamfetol 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis
Status: COMPLETED
Conditions: Drug-Induced Liver Injury
Interventions: DRUG: IV N-acetylcysteine (NAC)|DRUG: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Placebo|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: eFIT: An Internet-based Intervention to Increase Physical Activity in Persons With MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: eFIT Intervention|BEHAVIORAL: eJournal Intervention|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Prediction Rules for Identifying Patients With Chronic Neck Pain Who Will Benefit From General Aerobic Exercise
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: physical therapy treatment with aerobic exercise|OTHER: physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Safety, Efficacy and Mode of Action of Apremilast in Moderate Suppurative Hidradenitis
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Apremilast|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multicenter Study of the Efficacy and Tolerance of Tacrolimus on Refractory Nephrotic Syndrome (RNS)
Status: COMPLETED
Conditions: Kidney Diseases|Nephrotic Syndrome|Tacrolimus
Interventions: DRUG: tacrolimus (FK506)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CC-93269, a BCMA x CD3 T Cell Engaging Antibody, in Participants With Relapsed and Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: CC-93269
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Quetiapine in the Treatment of Refractory Social Anxiety Disorder in Adults
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Propelled Versus Standard Percutaneous Endoscopic Gastrojejunostomy(PEG-J); RCT
Status: TERMINATED
Conditions: Feeding Tube
Interventions: DEVICE: PEG-J placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients
Status: ENROLLING_BY_INVITATION
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Supported dCBT|BEHAVIORAL: Unsupported dCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Effects of an Inpatient Pulmonary Rehabilitation Program in Patients With Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: PROCEDURE: Inpatient Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability and Prophylactic Antiviral Activity of Neumifil Against Influenza Via a Human Viral Challenge Model
Status: COMPLETED
Conditions: Influenza Viral Infections
Interventions: DRUG: Neumifil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)
Status: RECRUITING
Conditions: Malaria Infection
Interventions: DRUG: M5717 60 mg|DRUG: Pyronaridine|DRUG: Atovaquone-Proguanil|DRUG: M5717 200 mg|DRUG: M5717 660mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks
Status: COMPLETED
Conditions: Lower Extremity Surgery|Upper Extremity Surgery|Post-operative Pain
Interventions: PROCEDURE: Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Health Benefits of a 21-day Daniel Fast
Status: COMPLETED
Conditions: Effects of Krill Oil on Human Health
Interventions: DIETARY_SUPPLEMENT: Krill oil supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer
Status: TERMINATED
Conditions: Extensive Stage Lung Small Cell Carcinoma|Limited Stage Lung Small Cell Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Questionnaire Administration|DEVICE: Tumor Treating Fields Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lumbar Fusion With The Icotec CF/PEEK Pedicle System In Combination With The Icotec CF/PEEK TLIF Cage ETurn™
Status: COMPLETED
Conditions: Degeneration of Lumbar Intervertebral Disc|Degenerative Spondylolisthesis
Interventions: PROCEDURE: 1- or 2-level spinal fusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been Treated
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: bimatoprost 0.03%/timolol 0.5% combination ophthalmic solution|DRUG: latanoprost 0.005% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Thiopental|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RESIST-ADT (Androgen Deprivation Therapy)
Status: COMPLETED
Conditions: Prostate Cancer|Physical Function
Interventions: BEHAVIORAL: Progressive Resistance Training Exercise|BEHAVIORAL: Flexibility and Balance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Psychologically-Based Physical Therapy Treatment for Deployed U.S. Sailors and Marines With Musculoskeletal Injuries
Status: COMPLETED
Conditions: Musculoskeletal Injury
Interventions: BEHAVIORAL: Psychologically - Based Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexion
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Botulinum toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Stimulation (VeNS), Compared to a Sham Control For The Management Of Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: VeNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia After Total Knee Arthroplasty
Status: TERMINATED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DRUG: Ropivacaine, Ketorolac, adrenaline|DRUG: Ropivacaine Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Incidence and Consequences of Disorders of Glycosylation in Patients With Conotruncal and Septal Heart Defects"
Status: UNKNOWN
Conditions: Congenital Heart Diseases|Conotruncal Defects|Congenital Disorder of Glycosylation|Antithrombin III Deficiency
Interventions: OTHER: none intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|BIOLOGICAL: Nivolumab|BIOLOGICAL: Cabiralizumab|PROCEDURE: Tumor biopsy|PROCEDURE: Bone marrow|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma
Status: TERMINATED
Conditions: Esophageal Cancer|Gastric Cancer|Adenocarcinoma
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Raltegravir (MK0518) in HIV-Infected Patients Failing Current Antiretroviral Therapies (MK0518-018 EXT2)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: raltegravir potassium|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: GLUMA DESINSITIZER|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Neurosurgical Wound Infections
Status: COMPLETED
Conditions: Surgical Wound Infections
Interventions: DRUG: Vancomycin|DRUG: Placebo (Saline Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Masitinib (6.0)|DRUG: Riluzole|DRUG: Placebo|DRUG: Masitinib (4.5)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT