pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration
Status: RECRUITING
Conditions: Autosomal Dominant Polycystic Kidney Disease|Nephrogenic Diabetes Insipidus|Acquired Nephrogenic Diabetes Insipidus|Congenital Nephrogenic Diabetes Insipidus
Interventions: DRUG: PB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercising Together: An Intervention for Prostate Cancer Survivors and Spouses
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Randomized Exercise Intervention|BEHAVIORAL: Randomized Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive Decline and Alzheimer's Disease in the Dallas Lifespan Brain Study
Status: COMPLETED
Conditions: Alzheimer Disease|Cognitive Decline
Interventions: DRUG: [18F]AV-1451|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-term Cervical Spinal Cord Stimulation in Patients With Disorders of Consciousness After Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Coma|Stroke
Interventions: DEVICE: SCS|OTHER: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erbitux Study of CPT11, Oxaliplatin, UFToral Targeted Therapy
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: Irinotecan|DRUG: Oxaliplatin|DRUG: UFT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Postoperative Pain Management on Immune Function After Laparoscopic Resection of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DRUG: fentanyl-based analgesia|DRUG: local anesthetic wound infiltration-based anlagesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Buntanetap/Posiphen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensorimotor Block Dynamics and Hemidiaphragmatic Palsy: Selective Trunk Block vs Supraclavicular Brachial Plexus Block
Status: RECRUITING
Conditions: Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Selective Trunk Block (SeTB)|PROCEDURE: Supraclavicular Brachial Plexus Block (SC BPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG)
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft
Interventions: PROCEDURE: Apnea|PROCEDURE: High frequency ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketoconazole on Biliary Excretion of AZD0837
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD0837|DRUG: Ketoconazole|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: Photodynamic therapy|OTHER: Control Group|DEVICE: Diode Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: Progestin|DRUG: Clomiphene Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Allo-HSCT in ND HR-CBF-AML
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Diabetic Macular Edema (DME) With Anti-VEGF and Focal Laser
Status: COMPLETED
Conditions: Diabetic Retinal Edema
Interventions: DRUG: Ranibizumab 0.5 MG/0.05 ML Intraocular Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparative Study Between Ultrasound-guided Quadratus Lumborum Block Versus Fascia Iliaca Compartment Block for Postoperative Pain and Cognitive Dysfunction Management in Patient Undergoing Hip Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain and Cognitive Dysfunction Management in Hip Surgery
Interventions: PROCEDURE: peripheral nerve block|DRUG: PCA device as rescue medication with IV morphine 1mg if VAS more than 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Semaglutide on Pituitary Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Semaglutide 7 MG Oral Tablet|DRUG: Placebo|DRUG: Semaglutide 14 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ropivacaine|DRUG: Ketorolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: AMY-101|OTHER: Water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PROtective Ventilation Using Open Lung Approach Or Not Trial
Status: COMPLETED
Conditions: Postoperative Pulmonary Complications|Respiratory Insufficiency
Interventions: PROCEDURE: open lung approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Chemotherapy for Potentially Resectable Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Tegafur, Gimeracil and Oteracil Potassium Capsules；Oxaliplatin|DRUG: Tegafur, Gimeracil and Oteracil Potassium Capsules；Oxaliplatin|DRUG: Oxaliplatin; Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Exercise on Cognitive Function and Brain-derived Neurotrophic Factor in Young Adults
Status: COMPLETED
Conditions: Physical Conditioning, Human|Cognition
Interventions: BEHAVIORAL: High intensity aerobic exercise|BEHAVIORAL: Low intensity aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) for Chemotherapy Induced Peripheral Neuropathy (CIPN)
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy|Pain|Neuropathy
Interventions: DEVICE: High-Dose TENS|DEVICE: Low-Dose TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder
Status: TERMINATED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Cariprazine Oral Capsule [Vraylar]|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol (Vitamin D3)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chitosan Dressings to Facilitate Safe Effective Debridement of Chronic Wounds & Minimize Wound Bacterial Re-colonization
Status: TERMINATED
Conditions: Wound Debridement
Interventions: DEVICE: HemCon Dressings and HemCon ChitoGauze; chitosan-based.|DEVICE: Gauze and saline dressings.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Diabetes Prevention Program Pilot Study
Status: COMPLETED
Conditions: PreDiabetes|Overweight and Obesity|Type 2 Diabetes|Overweight, Childhood|Obesity, Childhood|Lifestyle, Healthy
Interventions: BEHAVIORAL: National Diabetes Prevention Program Lifestyle Intervention (DPP)|BEHAVIORAL: Family Diabetes Prevention Program (Family DPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: CHF 5074 1x|DRUG: CHF 5074 2x|DRUG: CHF 5074 3x|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure (POF)
Status: UNKNOWN
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: Intraovarian injection of Adipose derived Stromal cells (ADSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: CAPOX|DRUG: Capecitabine|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study
Status: RECRUITING
Conditions: Cavernous Sinus Meningioma|Proton-therapy|Photon Radiotherapy|Cognitive Impairment
Interventions: RADIATION: Proton-therapy|RADIATION: Photon radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study Comparing Efficacy and Safety of ATV/RTV+3TC With ATV/RTV+TDF/FTC in HIV-Infected, Treatment Naïve Subjects, Followed by Treatment With ATV/RTV+3TC
Status: TERMINATED
Conditions: HIV
Interventions: DRUG: Atazanavir|DRUG: Ritonavir|DRUG: Lamivudine|DRUG: Tenofovir/Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Reassessment Versus Procalcitonin in Order to Shorten Antibiotic Duration in Community-acquired Pneumonia
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: OTHER: the clinical reassessment arm|OTHER: the procalcitonin arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Hyomental Distance Measured Ultrasonography Versus Weight-based Criteria for Laryngeal Mask Size Selection in Children
Status: RECRUITING
Conditions: Laryngeal Mask Airway
Interventions: DEVICE: ultrasound guided hyomental distance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Early-phase Telecare Programs for Minor Stroke
Status: NOT_YET_RECRUITING
Conditions: Minor Stroke
Interventions: BEHAVIORAL: Psychoeducation|BEHAVIORAL: Computerised Cognitive Stimulation|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Automatic Versus Intentional Movement Exercises to Enhance Arm Functions After Stroke
Status: UNKNOWN
Conditions: Stroke|Upper-limb Paresis
Interventions: OTHER: motor training|OTHER: motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remediation of Emotional Processing Deficits in MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Emotional Processing Training|BEHAVIORAL: Placebo control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Abdominal Drainage vs no Drainage After Distal Pancreatectomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pancreatic Fistula|Distal Pancreatectomy|Drainage
Interventions: PROCEDURE: Avoid surgical drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gabapentin in the Prevention of Nausea and Vomiting Induced by Chemotherapy
Status: COMPLETED
Conditions: Vomiting|Cisplatin Adverse Reaction
Interventions: DRUG: Placebo|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of GSKs' MMR Vaccine (209762) vs. M-M-R® II, When Given With Routine Vaccines at 12-15 Months of Age
Status: COMPLETED
Conditions: Rubella|Mumps|Measles|Measles-Mumps-Rubella Vaccine
Interventions: BIOLOGICAL: GSK Biological's investigational vaccine 209762|BIOLOGICAL: M-M-R® II (Merck and Co)|BIOLOGICAL: Varivax®|BIOLOGICAL: Havrix®|BIOLOGICAL: Prevnar®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Neoplasms|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Camrelizumab|DRUG: Pyrotinib|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Paclitaxel|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Myoinositol and Metformin in PCO
Status: UNKNOWN
Conditions: PCOS
Interventions: DRUG: Metformin Hydrochloride|DRUG: Myo-inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ANAVEX2-73 Study in Patients With Rett Syndrome
Status: COMPLETED
Conditions: Rett Syndrome
Interventions: DRUG: ANAVEX2-73|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video Game Play to Alleviate Adolescent Anxiety
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: Eco-Rescue|BEHAVIORAL: Bejelewed 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders
Status: TERMINATED
Conditions: Anxiety Disorder|Anxiety Disorder of Childhood|Separation Anxiety Disorder of Childhood, Early Onset|Specific Phobia|Social Anxiety Disorder|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Combined ABMT and CBT|BEHAVIORAL: Combined Sham ABMT and CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alimta, Carboplatin and Radiation Therapy for Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Inoperable Non Small Cell Lung Cancer
Interventions: DRUG: Premetrexed (Alimta)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Banding Ligation With Carvedilol Versus Carvedilol for the Prevention of First Bleeding
Status: TERMINATED
Conditions: Variceal Bleeding
Interventions: PROCEDURE: EVL + carvedilol|DRUG: carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Lisinopril Tablets 40 mg Under Fed Condition
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Lisinopril Tablets 40 mg|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systems Biology of Gastrointestinal and Related Diseases
Status: TERMINATED
Conditions: Ulcerative Colitis|Crohn Disease|Obesity|Colon Polyp|Eosinophilic Esophagitis|GERD|Gastro Esophageal Reflux|Barrett Esophagus|Esophageal Cancer|Gastritis|Gastric Ulcer|Duodenal Ulcer|Intestinal Metaplasia|Gastric Cancer|Lymphocytic Colitis|Microscopic Colitis|Celiac Sprue|IBS|Irritable Bowel Syndrome|SIBO|NAFLD|Gallstone Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GEM-CLARIDEX: Ld vs BiRd
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Clarithromycin|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of T8 on Treating Chronic Abnormal Immune Activation in HIV/AIDS Patients
Status: COMPLETED
Conditions: Chronic Abnormal Immune Activation in HIV/AIDS
Interventions: DRUG: T8 tablet 0.5mg|DRUG: T8 tablet 1mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The ESTxENDS Trial- Substudy on Effects of Using Electronic Nicotine Delivery Systems (ENDS) on Olfactory Function
Status: COMPLETED
Conditions: Smoking Cessation|Olfactory Disorder
Interventions: OTHER: ENDS (vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: DRUG: Experimental Dentifrice|DRUG: Placebo Control Dentifrice|DRUG: Reference Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of IGF-I in HIV Metabolic Disease
Status: TERMINATED
Conditions: HIV Lipodystrophy
Interventions: DRUG: mecasermin|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injection
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer Recurrent
Interventions: DRUG: Doxorubicin Hydrochloride Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ImPact of Trimetazidine on MicrOcirculation After Stenting for Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Microcirculation|Vascular Resistance
Interventions: DRUG: trimetazidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Automatic Multimodal Assessment of Occurrence and Intensity of Pain for Research and Clinical Use
Status: COMPLETED
Conditions: Rotator Cuff Injuries
Interventions: BEHAVIORAL: Triangular Forearm Support|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: BPX-501 T Cells Infused Post Stem Cell Transplant in Pediatrics With Non-Malignant Disorders Ineligible for BPU004 Study
Status: NO_LONGER_AVAILABLE
Conditions: Hurler Syndrome|Inherited Metabolic Disorder|Lysosomal Storage Disorder|Metachromatic Leukodystrophy|Inborn Errors of Metabolism
Interventions: BIOLOGICAL: rivogenlecleucel|DRUG: rimiducid
Study Type: EXPANDED_ACCESS
Clinical trial: 6 FEC 100 Vs 4 FEC 100 Followed by 4 Taxol in N+ Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: 6 FEC 100|PROCEDURE: 4 FEC 100 followed by 4 Taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of R-HAD Alone or in Combination With Bortezomib in Patients With Relapsed or Refractory MCL
Status: UNKNOWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: High dose Ara-C|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLOC-ICH: Interleukin-1 Receptor Antagonist in Intracerebral Haemorrhage
Status: COMPLETED
Conditions: Intracerebral Haemorrhage
Interventions: DRUG: IL-1Ra Kineret®|OTHER: IL-1Ra Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: GTx-024|DRUG: GTx-024|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Group Acupuncture Therapy With Modified Yoga
Status: COMPLETED
Conditions: Chronic Neck Pain|Chronic Low Back Pain|Osteoarthritis Pain
Interventions: OTHER: Acupuncture Therapy Treatments|OTHER: Yoga Therapy Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Histology and Metabolism Following Total Pancreatectomy and Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Total Pancreatectomy|Pancreaticoduodenectomy|Pancreatic Diabetes|Non-Alcoholic Fatty Liver Disease|Metabolic Complication|Diabetes Mellitus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Feasibility Study Comparing Usual Foot Education and Phone App Alerts in Patients With Increased Risk of Diabetic Foot
Status: UNKNOWN
Conditions: Diabetic Foot|Diabetic Foot Ulcer
Interventions: DEVICE: Phone application|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Acapella on Spirometry Measures in Patients With Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis
Interventions: DEVICE: Acapella device|OTHER: Only routine chest physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma
Status: COMPLETED
Conditions: Asthma|GERD
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness in Endometrial and Cervical Cancer
Status: RECRUITING
Conditions: Gynecologic Cancer|Endometrial Cancer|Cervical Cancer|Quality of Life|Opioid Use
Interventions: BEHAVIORAL: Headspace Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)
Status: COMPLETED
Conditions: Insulin Resistance|Metabolic Syndrome|Obesity|Diabetes|NAFLD|Inflammation
Interventions: OTHER: Limited dairy diet|OTHER: Low-fat dairy diet|OTHER: Full-fat dairy diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Contrast Computed Tomography Versus Native Computed Tomography in Patients With Acute Abdomen and Impaired Renal Function
Status: RECRUITING
Conditions: Acute Abdomen|Radiocontrast Nephropathy
Interventions: DIAGNOSTIC_TEST: Abdominal or body CT with intravenous contrast|DIAGNOSTIC_TEST: Abdominal or body CT without intravenous contrast (native CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Cordyceps Militaris Beverage on the Immune Response
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Functional beverages from the submerged fermentation of Cordyceps militaris|OTHER: Fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate of Efficacy and Safety of Ginsengberry Concentrate on Fatigue.
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Ginsengberry concentrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Less Than 100 Hours Hospital Stay After Pancreatico-duodenectomy, RCT
Status: UNKNOWN
Conditions: Pancreas Cancer
Interventions: OTHER: Fast track Care pancreatico-duodenectomy.|OTHER: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel + Cisplatin + Gemcitabine in Untreated Metastatic Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: nab-Paclitaxel + Cisplatin + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission
Status: COMPLETED
Conditions: Malaria|Non-malarial Febrile Illness
Interventions: DRUG: Artemether-Lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adecatumumab Relative to FOLFOX After R0 Resection of Colorectal Liver Metastases
Status: COMPLETED
Conditions: Liver Metastases|Colorectal Cancer
Interventions: DRUG: Adecatumumab|DRUG: Adecatumumab and FOLFOX|DRUG: FOLFOX 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Analysis of Hemiparetics Adults Patients With Quadripod Cane and Rolling Cane
Status: UNKNOWN
Conditions: Stroke|Hemiplegic Gait
Interventions: DEVICE: Gait analysis with rolling cane|DEVICE: Gait analysis with quadripod cane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: VALTREX Once Daily For Viral Shedding In Herpes Simplex Virus 2 (HSV-2) Seropositive Subjects. VALTREX® Tablet is a Trademark of GlaxoSmithKline Group of Companies.
Status: COMPLETED
Conditions: Infections, Herpesviridae
Interventions: DRUG: Valaciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalation Study of P1101 in Healthy Adult Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: P1101 (24 mcg)|DRUG: P1101 (48 mcg)|DRUG: P1101 (90 mcg)|DRUG: P1101 (180 mcg)|DRUG: P1101 (225 mcg)|DRUG: P1101 (270 mcg)|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Cerebral Stroke
Interventions: DRUG: Drug: Normal Saline|DRUG: Sovateltide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect and Mechanism of Auricular Point Stimulation on Functional Dyspepsia With Sleep Disorder
Status: RECRUITING
Conditions: Functional Dyspepsia|Sleep Disorder
Interventions: BEHAVIORAL: Ear point pressure bean method in ear concha area|BEHAVIORAL: Ear point pressure bean method in earlobe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Actinium Ac 225-DOTA-Daratumumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Daratumumab|PROCEDURE: Echocardiography|DRUG: Fludarabine|PROCEDURE: Hematopoietic Cell Transplantation|BIOLOGICAL: Indium In 111-DOTA-Daratumumab|DRUG: Melphalan|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Radionuclide Imaging|PROCEDURE: Single Photon Emission Computed Tomography|DRUG: Sirolimus|DRUG: Tacrolimus|RADIATION: Total Marrow and Lymphoid Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Anabolic and Catabolic Effect of Loaded and Unloaded Exercise on Articular Cartilage Health
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Control Condition|OTHER: +12% Body Mass|OTHER: -12% Body Mass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Angiotensin 2 for AKI After OLT
Status: ENROLLING_BY_INVITATION
Conditions: Cirrhosis, Liver|End Stage Liver DIsease|Acute Kidney Injury|Liver Transplant; Complications
Interventions: DRUG: Angiotensin II|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre
Status: RECRUITING
Conditions: Scleroderma|Systemic Sclerosis
Interventions: BIOLOGICAL: Blood samples|OTHER: Biopsy|OTHER: Bronchoalveolar samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brigatinib and Binimetinib in Treating Patients With Stage IIIB-IV ALK or ROS1-Rearranged Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: ALK Gene Rearrangement|Lung Non-Small Cell Carcinoma|Progressive Disease|ROS1 Gene Rearrangement|Stage IIIB Lung Cancer|Stage IIIC Lung Cancer|Stage IV Lung Cancer|Stage IVA Lung Cancer|Stage IVB Lung Cancer
Interventions: DRUG: Binimetinib|DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Urine Alkalinazation on Urinary Inflammatory Markers in Patients With Cystinuria
Status: COMPLETED
Conditions: Cystinuria|Renal Lithiasis|Glomerulonephritis|Interstitial Nephritis
Interventions: DIETARY_SUPPLEMENT: Potassium citrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Optimizing Transfusion Thresholds in Critically-ill Children With Anaemia
Status: UNKNOWN
Conditions: Anemia
Interventions: PROCEDURE: Less red blood cell transfusions|PROCEDURE: More red blood cell transfusion (standard transfusion strategy in PICU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Myocardial Infarction
Interventions: BIOLOGICAL: High Dose Trivalent Influenza Vaccine|BIOLOGICAL: Standard Dose Quadrivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Efficacy Against Rotavirus Diarrhea; Vaccine Given With Routine Childhood Vaccinations in Healthy African Infants
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix™|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Treatment of Posttraumatic Stress Disorder Enhanced by Virtual Reality for Individuals With PTSD and Substance Abuse
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Substance Abuse
Interventions: OTHER: Cognitive behavioral treatment enhanced by virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the E/e' Ratio of the Mitral Annulus in Predicting Fluid Responsiveness.
Status: COMPLETED
Conditions: Left Ventricular Function Diastolic Dysfunction|Fluid Responsiveness
Interventions: OTHER: Volume expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Selpercatinib|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Rifaximin in Preventing Campylobacteriosis
Status: COMPLETED
Conditions: Dysentery|Diarrhea|Enteric Campylobacteriosis
Interventions: BIOLOGICAL: Rifaximin intervention|BIOLOGICAL: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Oral Carbohydrate and Postoperative Recovery in Diabetic Patients
Status: COMPLETED
Conditions: Gastrointestinal Surgery
Interventions: DIETARY_SUPPLEMENT: Oral carbohydrate (Outfast)|OTHER: Routine fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Peel Force of New Adhesives From the Skin
Status: COMPLETED
Conditions: Stoma Ileostomy
Interventions: OTHER: Standard adhesive 1|OTHER: Standard adhesive 2|OTHER: Standard adhesive 3|OTHER: P-4|OTHER: P-15|OTHER: P-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Study of the BX VELOCITY Stent In Patients With De Novo Coronary Artery Lesions.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: sirolimus-coated Bx Velocity stent|DEVICE: uncoated Bx Velocity stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Matuzumab Treatment With Epirubicin, Cisplatin and Capecitabine (ECX) in Esophago-Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Matuzumab|DRUG: Epirubicin|DRUG: Cisplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Antioxidant Sugar vs Granulated Sugar on Metabolic Outcomes in Healthy and Cardio Metabolic Subjects
Status: TERMINATED
Conditions: Gene Expression|Cardiometabolic Risk|Metabolic Syndrome
Interventions: OTHER: Study 1: MRBS|OTHER: Study 2: White sugar & education module|OTHER: Study 2: MRBS & education module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)
Interventions: DRUG: Epcoritamab|DRUG: Prednisone|DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Obinutuzumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Boceprevir in Asia Pacific Participants With Chronic Hepatitis C Genotype 1 (P07063)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Boceprevir (BOC)|DRUG: Placebo to boceprevir|DRUG: Peginterferon alfa-2b (PEG)|DRUG: Ribavirin (RBV)|DRUG: Cross-Over Boceprevir Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-VEC With Chemotherapy or Endocrine Therapy in Treating Participants With HER2- Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Estrogen Receptor Positive|HER2/Neu Negative|Invasive Breast Carcinoma|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Breast Carcinoma
Interventions: DRUG: Anastrozole|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Letrozole|DRUG: Paclitaxel|BIOLOGICAL: Talimogene Laherparepvec|DRUG: Tamoxifen|DRUG: Nab paclitaxel|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Recurrent and Refractory Ovarian, Fallopian Tube and Peritoneal Carcinoma
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Indinavir|DRUG: Zidovudine|DRUG: Lamivudine|DRUG: Nevirapine|PROCEDURE: Blood testing|PROCEDURE: Lymph node biospy|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hetrombopag or Placebo in Treatment-Naive Severe Aplastic Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Hetrombopag Olamine+Standard Therapy|DRUG: Placebo+Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
Status: COMPLETED
Conditions: All Diagnosed Health Conditions|ADD/ADHD|Alopecia Areata|Ankylosing Spondylitis|Asthma|Atopic Dermatitis Eczema|Beta Thalassemia|Bipolar Disorder|Breast Cancer|Celiac Disease|Cervical Cancer|Chronic Inflammatory Demyelinating Polyneuropathy|Chronic Kidney Diseases|Chronic Obstructive Pulmonary Disease|Colon Cancer|Colorectal Cancer|Crohn's Disease|Cystic Fibrosis|Depression|Diabetes Mellitus|Duchenne Muscular Dystrophy|Endometriosis|Epilepsy|Facioscapulohumeral Muscular Dystrophy|G6PD Deficiency|General Anxiety Disorder|Hepatitis B|Hereditary Hemorrhagic Telangiectasia|HIV/AIDS|Human Papilloma Virus|Huntington's Disease|Idiopathic Thrombocytopenic Purpura|Insomnia|Kidney Cancer|Leukemia|Lung Cancer|Lupus Nephritis|Lymphoma|Melanoma|Multiple Myeloma|Multiple Sclerosis|Myositis|Myotonic Dystrophy|Ovarian Cancer|Pancreatic Cancer|Parkinson's Disease|Polycystic Kidney Diseases|Prostate Cancer|Psoriasis|Psoriatic Arthritis|Rosacea|Scleroderma|Sickle Cell Anemia|Sickle Cell Trait|Sjogren's Syndrome|Skin Cancer|Spinal Muscular Atrophy|Systemic Lupus Erythematosus|Thrombotic Thrombocytopenic Purpura|Trisomy 21|Ulcerative Colitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Eflornithine|DRUG: Eflornithine Placebo|DRUG: Sulindac 150 MG|DRUG: Sulindac placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mini Screw Implant Supported Pontics Versus Removable Partial Dentures For Restoring Missing Permanent Anterior Teeth
Status: NOT_YET_RECRUITING
Conditions: Missing Teeth
Interventions: OTHER: mini-screw implant|DEVICE: removable partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nelfinavir in Recurrent Adenoid Cystic Cancer of the Head and Neck
Status: COMPLETED
Conditions: Carcinoma, Adenoid Cystic|Head and Neck Neoplasms
Interventions: DRUG: Nelfinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound in PD Patients
Status: COMPLETED
Conditions: Peritoneal Dialysis|Hypervolemia|VEGF Overexpression
Interventions: DIAGNOSTIC_TEST: NT-BNP, VEGF|DIAGNOSTIC_TEST: Echocardiography|RADIATION: Chest Radiography|DIAGNOSTIC_TEST: Lung Ultrasound|DIAGNOSTIC_TEST: Bioelectrical Impedence Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NEPA to Prevent Chemotherapy Induced Nausea and Vomiting in Patients With Breast Cancer
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Netupitant/Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION