pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia
Status: ENROLLING_BY_INVITATION
Conditions: Anesthesia
Interventions: DRUG: Oxycodone 20 Mg Oral Tablet|DRUG: Pregabalin 150mg|DRUG: Multivitamin with Minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Adalat LA and Coracten on Drug Levels, Blood Pressure, and Heart Rate in Fed Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Adalat (Nifedipine, BAYA1040)|DRUG: Coracten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extracorporal Shock Wave Treatment to Improve Nerve Regeneration
Status: UNKNOWN
Conditions: Peripheral Nerve Injury
Interventions: DEVICE: MTS Medical UG Orthogold 100|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ProAliFun_6.5_Health Effects of a Functional Pasta Enriched With Barley Beta-glucans on Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Beta-glucans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study in Intensive Care Patients to Investigate the Clinical Effect of Repetitive Orally Inhaled Doses of AP301 on Alveolar Liquid Clearance in Acute Lung Injury
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: AP301|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Immune-related Biomarkers to Predict the Efficacy of Cancer Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Metastatic|Locally Advanced Malignant Neoplasm|Non Hodgkin Lymphoma|Urologic Neoplasms
Interventions: PROCEDURE: Blood sample collection|PROCEDURE: Biopsy collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antiorbital Calcium in Chronic Conditions
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DIETARY_SUPPLEMENT: Ionic Calcium|DIETARY_SUPPLEMENT: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices
Status: RECRUITING
Conditions: Complex Aortic Aneurysms|Thoracoabdominal Aneurysms|Pararenal Aneurysms|Juxtarenal Aneurysms|Marfan Syndrome|Ehlers-Danlos Syndrome|Loeys-Dietz Syndrome|Aortic Arch Aneurysm
Interventions: DEVICE: Custom Made Fenestrated or Branched Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Peri-procedure Blood Pressure Management of Revascularization
Status: UNKNOWN
Conditions: Cerebral Revascularization|Ischemic Cerebrovascular Disease
Interventions: OTHER: model controlling|OTHER: conventional controlling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Aplastic Anemia|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Myelodysplastic Syndromes|Chronic Eosinophilic Leukemia|Chronic Myelomonocytic Leukemia|Chronic Neutrophilic Leukemia|Essential Thrombocythemia|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Juvenile Myelomonocytic Leukemia|Mastocytosis|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Nodal Marginal Zone B-cell Lymphoma|Polycythemia Vera|Previously Treated Myelodysplastic Syndromes|Primary Myelofibrosis|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Recurrent/Refractory Childhood Hodgkin Lymphoma|Refractory Anemia|Refractory Anemia With Ringed Sideroblasts|Refractory Hairy Cell Leukemia|Refractory Multiple Myeloma|Secondary Myelodysplastic Syndromes|Splenic Marginal Zone Lymphoma|T-cell Large Granular Lymphocyte Leukemia|Waldenström Macroglobulinemia
Interventions: DRUG: Fludarabine|DRUG: Busulfan|RADIATION: Total Body Irradiation (TBI)|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|DRUG: Cyclophosphamide (CY)|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DEVICE: Allogeneic hematopoietic stem cell transplantation|PROCEDURE: Peripheral blood stem cell transplantation (PBSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Orally Administered Rob 803 When Added to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rob 803|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eficacy of Long-term Suplementation With Docosahexaenoic Acid in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid administration: 50 mg/kg/day during 12 months|DIETARY_SUPPLEMENT: Placebo: 50 mg/kg/day during 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Vaccination in Treated HIV Disease
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: PENNVAX-GP|BIOLOGICAL: INO-6145|BIOLOGICAL: INO-9012|DEVICE: CELLECTRA® 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Healing Touch on Patients Undergoing Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Anxiety Disorder|Fatigue|Hematopoietic/Lymphoid Cancer|Pain
Interventions: PROCEDURE: therapeutic touch|OTHER: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Locomotor Learning With Brain Stimulation
Status: COMPLETED
Conditions: Motor Learning
Interventions: BEHAVIORAL: Motor Imagery (MI)|DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Accuracy of the Apple Watch Series 4 for Detection of Heart Rhythm: A Pilot Study
Status: COMPLETED
Conditions: Heart Rate Fast|Heart Rate Low
Interventions: DEVICE: Apple Watch 4 Series Device|DEVICE: Continuous Telemetry Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adoptive Immunotherapy, Aldesleukin, and Zoledronate in Treating Patients With Stage IV Kidney Cancer and Lung Metastases
Status: COMPLETED
Conditions: Kidney Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant and Immunomodulatory Effect of a β-glucan Fiber From Saccharomyces Cerevisiae
Status: COMPLETED
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Yeast β-glucan fiber|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: ART with Equia|PROCEDURE: ART with Giomer Beautifil-Bulk Restorative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Schizophrenia Trial of Aripiprazole
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Olanzapine or Quetiapine or Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrinsic Foot Muscle Training With and Without Hip Abductor Muscle Strengthening in Pronation Distortion Syndrome
Status: RECRUITING
Conditions: Pronation Deformity of the Foot
Interventions: OTHER: Intrinsic foot muscle training|OTHER: Hip abductor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Invasive Fungal Disease
Interventions: DRUG: Liposomal amphotericin B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery
Status: COMPLETED
Conditions: Tranexamic Acid|Trauma|Lower Extremity Fracture
Interventions: DRUG: Tranexamic acid injection|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer (NURE-Combo)
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma
Interventions: DRUG: Nivolumab + Nab-paclitaxel|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin v Ciprofloxacin Added to Rifampicin + Ethambutol, for Opportunist Mycobacterial Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Diseases
Interventions: DRUG: Addition of clarithromycin to rifampicin and ethambutol|DRUG: Addition of Ciprofloxacin to rifampicin and ethambutol|BIOLOGICAL: Vaccination with M.vaccae
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR)
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: DRUG: metformin hydrochloride|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monovalent H5N1 Vaccine GSK1557484A in Children 6 Months to < 18 Years of Age
Status: COMPLETED
Conditions: Influenza|Influenza Vaccines
Interventions: BIOLOGICAL: Influenza A (H5N1) Virus monovalent vaccine|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Post-Concussive Syndrome
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy|PROCEDURE: Hyperbaric Oxygen Therapy|PROCEDURE: Hyperbaric Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of 610 in Patients With Severe Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: 610|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CLiCK in the Critical Care Unit
Status: RECRUITING
Conditions: Central Venous Catheter Thrombosis|Central Venous Catheter Related Bloodstream Infection|Catheter Complications|Catheter Blockage|Catheter Dysfunction|Central Line-associated Bloodstream Infection (CLABSI)|Catheter|Catheter Infection
Interventions: DEVICE: 4% EDTA|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Lychee Fruit Extract to Promote Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Health
Interventions: DIETARY_SUPPLEMENT: Lychee Fruit Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study: Intraoperative Clonidine and Postoperative Behaviour
Status: COMPLETED
Conditions: Negative Behaviour Change
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension
Status: UNKNOWN
Conditions: Hypotension|Shivering|Nausea and Vomiting|Vasopressor
Interventions: DRUG: ramosetron|DRUG: ondansetron|DRUG: ondansetron|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trans Abdominal Plane Block (TAP Block) in Surgery of Stoma Reversal and Its Effect on Post Operative Recovery: a Prospective, Randomized, Muticenter Study
Status: COMPLETED
Conditions: Surgery|Stoma Ileostomy
Interventions: PROCEDURE: Trans abdominal plane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|OTHER: Quality-of-Life Assessment|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HANDS-ON: a Personalized, Brief and Intensive Exposure-based Intervention for Youth With Persistent Anxiety or OCD
Status: RECRUITING
Conditions: Anxiety Disorders|Obsessive-Compulsive Disorder|Obsessive-Compulsive Disorder in Children|Obsessive-Compulsive Disorder in Adolescence
Interventions: BEHAVIORAL: HANDS-ON treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Immune Response in Adolescents Allergic to Peanut After Receiving Intradermal Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: DRUG: ASP0892|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Living Skills Intervention for 9th and 10th Graders With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Surviving and Thriving in the Real World|BEHAVIORAL: Program for the Education and Enrichment of Relational Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Pain|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy - Pain|BEHAVIORAL: Cognitive Behavioral Therapy-Integrated|BEHAVIORAL: Cognitive Processing Therapy - PTSD|BEHAVIORAL: Treat as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Stem Cell Transplantation in Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: iodine I 131 metaiodobenzylguanidine|DRUG: Fludarabine|DRUG: Thiotepa|PROCEDURE: T-cell depletion|PROCEDURE: Haploidentical stem cell transplantation|PROCEDURE: Donor Lymphocyte Infusion|DRUG: Rituximab|PROCEDURE: Co-transplantation of mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Ketamine for Blunt Thoracic Trauma
Status: COMPLETED
Conditions: Blunt Injury of Thorax|Multiple Rib Fractures, Involving Three Ribs
Interventions: DRUG: Ketamine 1 Mg/mL-NaCl 0.9% Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food and Calcium on Pharmacokinetics of a Single Dose of S-888711 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: S-888711|DIETARY_SUPPLEMENT: Calcium Antacid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion
Status: TERMINATED
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: Brolucizumab 6 mg|DRUG: Aflibercept 2 mg|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Trial of Oral Dispersible Praziquantel Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oral dispersible tablet of praziquantel (ODT-PZQ)|DRUG: Cysticide|DRUG: ODT-PZQ|DRUG: ODT-PZQ|DRUG: ODT-PZQ|DRUG: Cysticide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transnasal Induction of Normothermia for Neurogenic Fever
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Seizures|Metabolic Encephalopathy
Interventions: DEVICE: Transnasal Thermal Regulating Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety and Pharmacokinetics Study of Single Ascending Doses of BTA-C585 in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics|Healthy Volunteers
Interventions: DRUG: BTA-C585 oral capsules|DRUG: BTA-C585 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effects on Ovarian Activity of a Combined Oral Contraceptive Pill When Preceded by the Intake of ellaOne® or Placebo.
Status: COMPLETED
Conditions: Emergency Contraception
Interventions: DRUG: Ulipristal Acetate (UPA) + ethinylestradiol/levonorgestrel (Microgynon)|DRUG: placebo + ethinylestradiol/levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: lomustine|DRUG: procarbazine hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Sodium Lactate Infusion During Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DRUG: Sodium Lactate light dose|DRUG: Sodium Lactate high dose|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Crossover Study Comparing Sugammadex and Placebo
Status: COMPLETED
Conditions: Posterior Cervical Decompression and Fusion
Interventions: DRUG: Sugammadex Injection [Bridion]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Hematopoietic Stem Cell Transplantation|DEVICE: CliniMACS|DRUG: See intervention description
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Mental Health Therapies to Improve Military Readiness
Status: RECRUITING
Conditions: Anxiety|Alpha Stim|Cranial Electrotherapy Stimulation|Cognitive Behavioral Therapy|Heart Rate Variability
Interventions: DEVICE: Experimental: Alpha-Stim 100|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: capecitabine|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1a
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Fluorine-19-Fluoroded Xyglucose|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Influence of Noxious Electrical Stimulation on Chronic Pain From Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Noxious Electrical Stimulation (NxES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Vortioxetine in Adult ADHD Patients
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: vortioxetine 10 mg tablet|DRUG: vortioxetine 20 mg tablet|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tracking of Respiratory-Induced Tumor Motion Using Implanted Fiducials
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: CT Scans|PROCEDURE: Implanted markers|RADIATION: Radiation Treatment (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-Controlled Trial of Glutamine for Breast Cancer Patients With Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Neuropathy|Breast Cancer
Interventions: DRUG: glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Sequencing as a Strategy for Identifying Genetic Factors Associated With Serious Adverse Events After Covid-19 Vaccines in Use in Brazil
Status: RECRUITING
Conditions: Vaccine-induced Thrombotic Thrombocytopenia Syndrome|Guillain-Barre Syndrome|Acute Disseminated Encephalomyelitis|Transverse Myelitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stimulant Enhancement of Well-Being Therapy for Depression
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Amphetamine/dextroamphetamine|DRUG: Placebo|BEHAVIORAL: Well-being therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|OTHER: Placebo|DRUG: Prucalopride|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic, Comprehensive, One-to-One Training (SCOOT) for Scooter Skills: A Feasibility Study
Status: COMPLETED
Conditions: Mobility Scooter Skills Training
Interventions: OTHER: Systematic, Comprehensive, One to One Training (SCOOT)|OTHER: Six Week Delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of IBI310 Combined With Sintilimab in Patients With Advanced Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: IBI308 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma|Burkitt Lymphoma
Interventions: BIOLOGICAL: obinutuzumab|DRUG: prednisone|DRUG: Revlimid|BIOLOGICAL: Polatuzumab|DRUG: ibrutinib|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation
Status: WITHDRAWN
Conditions: Acute Lung Injury|Adult Respiratory Distress Syndrome|Kidney Injury
Interventions: DEVICE: Volume-Cycled Assist-Control (AC) mode|DEVICE: Airway Pressure Release Ventilation (APRV) mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbial Transplantation for C. Difficile and/or Ulcerative Colitis or Indeterminate Colitis
Status: COMPLETED
Conditions: Clostridium Difficile Infection|Ulcerative Colitis|Indeterminate Colitis
Interventions: BIOLOGICAL: Fecal Microbial Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeRioperative Omega Three and the Effect on ImmuNity
Status: COMPLETED
Conditions: Colorectal Cancer|Nutritional Deficiency|Infected Wound|Surgical Site Infection|Complication, Postoperative|Surgery|Surgery--Complications|Sarcopenia|Phagocytic Dysfunction
Interventions: DIETARY_SUPPLEMENT: Omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ACCELERATE: Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Pegfilgrastim and Darbepoetin Alfa Support for the Treatment of Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Neulasta|DRUG: Aranesp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy Supplements in Treating Patients Undergoing Surgery for Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: soy isoflavones|DIETARY_SUPPLEMENT: soy protein isolate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Positive Pressure Ventilation on Symptoms of Acute Mountain Sickness
Status: NOT_YET_RECRUITING
Conditions: Acute Mountain Sickness
Interventions: DEVICE: Continuous positive airway pressure (CPAP), ResMed AirMini
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Ammoxetine hydrochloride enteric-coated tablets|DRUG: Duloxetine hydrochloride enteric-coated capsules|DRUG: Placebo to Ammoxetine|DRUG: Placebo to Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Reflux After Sleeve Using Stretta
Status: TERMINATED
Conditions: GERD|Morbid Obesity
Interventions: DEVICE: Stretta|PROCEDURE: Radiofrequency (RF) Energy to the LES (Stretta Procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine in Immunosuppressed Adults With Autoimmune Diseases
Status: COMPLETED
Conditions: Covid19|Rheumatic Diseases|Rheumatoid Arthritis|SLE
Interventions: BIOLOGICAL: Moderna COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GRam Stain-guided Antibiotics ChoicE for Ventilator-Associated Pneumonia (GRACE-VAP) Trial
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: Gram stain-guided antibiotic choice|DRUG: Guidelines-based antibiotics choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: National Fully Remote Use of IpsiHand Device in Hemiparetic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Hemiparesis|Spasticity as Sequela of Stroke|Brain Computer Interface
Interventions: DEVICE: Neurolutions IpsiHand System|OTHER: Standard of Care - Home Exercise Program for Upper Extremity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-operative Depo Medroxyprogesterone Acetate on Serum Anti-mullerian Hormone Level After Laparoscopic Ovarian Cystectomy of Endometriomas
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: depot medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IBI362 Evaluating Weight Loss in Obese and Overweight Chinese Subjects
Status: COMPLETED
Conditions: Overweight/ Obesity
Interventions: DRUG: IBI362|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCD
Status: RECRUITING
Conditions: OTC Deficiency|Ornithine Transcarbamylase Deficiency|OTCD
Interventions: BIOLOGICAL: ARCT-810
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Action Observation Therapy (AOT) on Balance and Gait in Patients With Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Action Observation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Plus Apatinib for Advanced Non-Squamous NSCLC Previously Treated With First-Line Immunotherapy
Status: UNKNOWN
Conditions: Advanced Non Squamous NSCLC
Interventions: DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Perioperative Dexmedetomidine Administration on Immune Suppression and Outcomes in Patients With Uterine Cancer Undergoing Radical Resection
Status: COMPLETED
Conditions: Uterine Cancer
Interventions: DRUG: Dexmedetomidine group|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CPAP Effect on the Progression of Diabetic Retinopathy in Patients With Sleep Apnea
Status: COMPLETED
Conditions: Diabetic Retinopathy|Sleep Apnea
Interventions: DEVICE: Continuous positive airway pressure|DRUG: Pharmacological treatment|OTHER: Conventional anti-diabetic diet recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Connecting Families to Overcome Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BEHAVIORAL: Message-based Outreach Intervention for Survivors|BEHAVIORAL: Standard Outreach for Survivors|BEHAVIORAL: Message-based Outreach Intervention for Close Relatives|BEHAVIORAL: Standard Outreach for Close Relatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis
Status: UNKNOWN
Conditions: Cystic Fibrosis|Bronchiectasis
Interventions: DRUG: S-1226
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic vs Abdominal Radical Hysterectomy In Patients With Early Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Postoperative Pain
Interventions: PROCEDURE: Laparoscopic Radical Hysterectomy + pelvic lymphadenectomy|PROCEDURE: Abdominal radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986207 Given Alone and in Combination With Nivolumab or With Nivolumab and Ipilimumab in Advanced Solid Tumors
Status: COMPLETED
Conditions: Broad Solid Tumor
Interventions: DRUG: BMS-986207|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Cisplatin, and Topotecan With or Without Filgrastim in Treating Patients With Newly Diagnosed Stage III or Stage IV Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Brenner Tumor|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mixed Epithelial Carcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Undifferentiated Adenocarcinoma|Stage III Ovarian Epithelial Cancer|Stage IV Ovarian Epithelial Cancer
Interventions: DRUG: paclitaxel|DRUG: cisplatin|DRUG: topotecan hydrochloride|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FLUTIFORM® VS Seretide® in Paediatric Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FLUTIFORM® (Formoterol fumarate / Fluticasone propionate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Combined Mode-Kinetic Chain Exercise With and Without Core Stability Exercises on Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Mode-Kinetic Chain Exercise With Core Stability Exercises|OTHER: Mode-Kinetic Chain Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Immediate Post Placental Insertion of Intrauterine Device During Cesarean Delivery
Status: COMPLETED
Conditions: Contraception Behavior
Interventions: DEVICE: Copper Intra uterine contarceptive device ( Cu-T 380A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CMOP Regimen and Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Newly Diagnosed Peripheral T-cell Lymphoma
Interventions: DRUG: CMOP+Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4 (EMERGENE)
Status: RECRUITING
Conditions: Limb-girdle Muscular Dystrophy
Interventions: BIOLOGICAL: SRP-9003|DRUG: Glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy
Status: UNKNOWN
Conditions: Kidney Diseases|Diabetes Mellitus|Acute Kidney Injury|Kidney Failure, Chronic|Renal Insufficiency
Interventions: DRUG: Alprostadil ﹠control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Screening for Monoclonal Gammopathy in Individuals Undergoing Physical Examinations Using iMS-LC Assay Technology.
Status: NOT_YET_RECRUITING
Conditions: M Protein|Monoclonal Gammopathy|Monoclonal Gammopathy of Undetermined Significance
Interventions: DIAGNOSTIC_TEST: M protein detection by iMS-LC Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Butyrate-enriched Triglyceride and Diabetes Prevention
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes|PreDiabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: butyrate/hexanoate-enriched triglycerides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of GFH009 Monotherapy in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Status: RECRUITING
Conditions: Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Interventions: DRUG: GFH009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplantation: International Lupus Trial
Status: WITHDRAWN
Conditions: REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS
Interventions: BIOLOGICAL: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benralizumab in Chronic Prurigo - Investigating Clinical Efficacy (BICPIC)
Status: WITHDRAWN
Conditions: Chronic Prurigo
Interventions: DRUG: Fasenra Prefilled Syringe|OTHER: Matching Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease
Status: RECRUITING
Conditions: Univentricular Heart|Congenital Heart Disease|Heart Failure NYHA Class III|Heart Failure NYHA Class IV
Interventions: BIOLOGICAL: iPSC-CL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onco-primary Care Networking to Support TEAM-based Care
Status: RECRUITING
Conditions: Blood Pressure|Hypertension|Cancer|Cancer, Breast|Cancer of Prostate|Cancer Colorectal|Cancer, Endometrial|Cancer of Head and Neck|Non Small Cell Lung Cancer|CVD - Cardiovascular Disease|Diabetes Mellitus|Hypercholesterolemia|Diabetes|Cancer of Esophagus|Cancer of Liver|Cancer, Renal Cell|Cancer of Pancreas|Cancer Ovaries
Interventions: BEHAVIORAL: iGuide Intervention (Self-guided)|BEHAVIORAL: iGuide 2 Intervention (Tailored/Targeted)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Glyburide vs Insulin trials|DRUG: Metformin vs Insulin trials|DRUG: Metformin vs Glyburide trials
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Non-face to Face Multidisciplinary Health Care Model in a Population With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Teleconsultation either by phone or by computer consultation. Quantitative and qualitative approaches to analysis|OTHER: Care modalities. Quantitative and qualitative approaches to analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single-Stage, Adaptive, Open-label, Dose Escalation Safety and Efficacy Study of AADC Deficiency in Pediatric Patients
Status: RECRUITING
Conditions: AADC Deficiency
Interventions: DRUG: AAV2-hAADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0148-0000-0362 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: NNC 0148-0000-0362|DRUG: insulin glargine|DRUG: placebo|DRUG: NNC 0148-0000-0362|DRUG: NNC 0148-0000-0362|DRUG: NNC 0148-0000-0362
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of tDCS on Cognition, Symptoms in Chronic Schizophrenia Patients With Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open-label, Parallel Study to Evaluate the Pharmacokinetic Characteristics of Pregabalin According to Different Controlled Released Formulations in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Vaginal Electrical Stimulation for Postpartum Neuromuscular Recovery
Status: COMPLETED
Conditions: Obstetric Anal Sphincter Injury|Vaginal Electrical Stimulation
Interventions: DEVICE: ApexM (Stimulation) Device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Gut-Lung Axis and Respiratory Illness in Children
Status: RECRUITING
Conditions: Respiration Disorders|Respiratory Disease|Asthma in Children|Wheezing|Gastro-Intestinal Disorder|Healthy
Interventions: OTHER: observational only - no interventions as part of study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p