pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Androgen Reduction in Congenital Adrenal Hyperplasia
Status: WITHDRAWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Abiraterone acetate|DRUG: Placebo|DRUG: Hydrocortisone|DRUG: Fludrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: DRUG: Three different mixture of acetate, butyrate and propionate and palcebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Anxiety|Quality of Life
Interventions: BEHAVIORAL: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TMC125, Darunavir; Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS Patients
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|ALS
Interventions: DRUG: PLL001 or placebo daily subcutaneous injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Nasopharyngeal Aspiration
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 88% sucrose po|DRUG: placebo po
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Analgesia in Combination With Cryoanalgesia to Prevent Acute Pain Following Nuss Procedure
Status: RECRUITING
Conditions: Acute Pain|Regional Anesthesia
Interventions: DEVICE: regional analgesia with cryolesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Novel α2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial
Status: RECRUITING
Conditions: Pulmonary Embolism
Interventions: DRUG: TS23|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Fasting and no Fasting Before Interventional Coronary Intervention on the Occurrence of Adverse Events
Status: UNKNOWN
Conditions: Fasting|Cardiac Catheterization|Percutaneous Coronary Intervention
Interventions: OTHER: Oral intake allowed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary
Interventions: DRUG: Etelcalcetide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplant (HSCT)|Endothelial Injury
Interventions: DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Accelerated Pacing in Patients Undergoing Pace-and-ablate Strategy With LBBAP: a Randomized Controlled Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Permanent Atrial Fibrillation|Persistent Atrial Fibrillation|Pacemaker DDD|Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Accelerated pacing|DEVICE: Current standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Digital App for Telerehabilitation in Respiratory Diseases
Status: RECRUITING
Conditions: Respiratory Disease|Asthma|Long COVID|Chronic Obstructive Pulmonary Disease|Obesity|Lung Fibrosis|Bronchiectasis
Interventions: OTHER: Home-based telerehabilitation program delivered through digital devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy Of Complete Mesocolic Excision With Central Vessel Ligation Technique On Lymph Nodes And Safety Margins Compared With Conventional Surgery For Colon Cancer Treatment
Status: UNKNOWN
Conditions: Cancer Colon
Interventions: PROCEDURE: Total Mesocolic Excision with Central Vessel Ligation|PROCEDURE: conventional surgery of cancer colon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract
Status: TERMINATED
Conditions: Colorectal Cancer|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Pancreatic Cancer|Small Intestine Cancer
Interventions: BIOLOGICAL: carcinoembryonic antigen peptide 1-6D|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder Combined Type|ADHD Predominantly Inattentive Type|ADHD Predominantly Hyperactivity Type|ADHD-not Other Specified
Interventions: DRUG: Methylphenidate- Ritalin IR (Immediate Release)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery
Status: COMPLETED
Conditions: Ambulatory Surgery
Interventions: DRUG: Administration of tramadol intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse Prevention
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence|Post-Traumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Enhanced-Cognitive Processing Therapy-C (E-CPT-C)|DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Clinical Evaluation of Nano-hybrid-composite Denture Teeth
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Mouth|Dental Prosthesis Failure
Interventions: DEVICE: Examination of dentures with SR Phonares II teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Human Proof of Concept Study for [11C]-RO5011232 as Radiotracer and Study of the Binding of RO4917523 to Human mGlu5 Brain Receptor at Steady-State in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO4917523|DRUG: RO5011232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: PreventIon of IMT Progression in iSchemic Stroke Patients With High Risk of Cerebral HemOrrhage-IMT Study
Status: UNKNOWN
Conditions: Brain Ischemia|Intracranial Hemorrhages
Interventions: DRUG: cilostazol|DRUG: Probucol|DRUG: Aspirin|DRUG: placebo of cilostazol|DRUG: Placebo of aspirin|DEVICE: Intima-medial thickness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dairy and Plant Amino Acid Uptake. An Explorative Study
Status: COMPLETED
Conditions: Amino Acid Plasma Profile
Interventions: DIETARY_SUPPLEMENT: Dairy protein|DIETARY_SUPPLEMENT: Plant protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing ImmunoResponse Post Eribulin: Eribulin and Immunogenicity in Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Female|Neoplasm, Breast|Breast Cancer Metastatic
Interventions: DRUG: Eribulin Injection [Halaven]|DRUG: Paclitaxel injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy
Status: UNKNOWN
Conditions: Systolic Heart Failure
Interventions: PROCEDURE: Image guided delivery of cardiac pacing leads.|PROCEDURE: Standard delivery of cardiac pacing leads.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month
Status: COMPLETED
Conditions: Fissure, Dental|Adhesion
Interventions: PROCEDURE: fissure sealant application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 Gene
Status: TERMINATED
Conditions: Epidermolysis Bullosa Dystrophica, Recessive|Epidermolysis Bullosa Dystrophica, Dominant
Interventions: DRUG: QR-313|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Additives Effects on EEG Profiles in College Students With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Artificial Food Coloring|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: OPTI-FREE RepleniSH|DEVICE: ReNu MultiPlus MPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Investigating the Use of a Positive Parenting Programme to Improve Treatment Adherence in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Self-directed Teen Triple P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DigitalEPI - A Prospective Pilot Study
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: EEG recording with the comparator device Micromed Brain Quick|DEVICE: EEG recording with the investigational device "Atlas with dry electrodes" clinic/specialized staff|DEVICE: EEG recording with the investigational device "Atlas with dry electrodes" home/lay people
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Immunogenicity of an Trivalent Inactivated Cell-Culture Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Prevention of Influenza
Interventions: BIOLOGICAL: NBP607|BIOLOGICAL: Agrippal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dysfunctional Breathing: Characterisation and Assessment
Status: UNKNOWN
Conditions: Respiration Disorder|Hyperventilation Syndrome|Breathlessness|Breath Shortness
Interventions: OTHER: Short-form survey instrument|OTHER: Demographic data|OTHER: Hospital Anxiety and Depression Scale|OTHER: Nijmegen questionnaire|OTHER: The Self-evaluation of breathing questionnaire|OTHER: six-minute exercise test|OTHER: Indirect calorimetry|OTHER: Oxygen saturation monitoring|OTHER: Heart rate variability analysis|OTHER: Continuous measurement of arterial blood pressure|DIAGNOSTIC_TEST: Lung function test|OTHER: Respiratory muscle function|OTHER: Manual assessment of respiratory motion|OTHER: Breath-hold test|OTHER: Physical Activity monitoring|OTHER: Asthma Control Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pancreatic Resectability in Cancers With Known Limited Extension (PRICKLE)
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Abraxane|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Pilot Study of Single-Dose Oral and Intravenous CTAP101 in Stage 3 and 4 Chronic Kidney Disease Subjects
Status: COMPLETED
Conditions: Chronic Kidney Disease|Secondary Hyperparathyroidism|Chronic Renal Insufficiency|Chronic Renal Failure
Interventions: DRUG: CTAP101 Capsules|DRUG: CTAP101 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SURVIVAL PLUSS: Increasing Capacity for Mama-baby Survival in Post-conflict Uganda and South Sudan
Status: COMPLETED
Conditions: Neonatal Death|Preterm Birth|Low Birthweight|Neonatal Hypoglycemia
Interventions: BEHAVIORAL: Intervention arm: An integrated package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Explore the Safety and Tolerability of Galantamine HBr in the Treatment of Pick Complex/Frontotemporal Dementia
Status: COMPLETED
Conditions: Frontotemporal Dementia|Pick Complex
Interventions: DRUG: galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer
Status: UNKNOWN
Conditions: Impotence|Prostatic Neoplasms
Interventions: DRUG: Sildenafil therapy plus post-NSRRP HBO2T|DRUG: Sildenafil therapy plus sham post-NSRRP HBO2T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Diaphragm Paralysis Due to Local Anesthesia|Anterior Suprascapular Nerve Block|Analgesia, Arthroscopic Shoulder Surgery
Interventions: OTHER: Evaluation of Diaphragm Movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of PCSK9 Inhibitors on Coronary Plaque Composition and Vulnerability Assessed by Optical Coherence Tomography
Status: COMPLETED
Conditions: Randomized Controlled Trials
Interventions: DRUG: PCSK9 inhibitor plus statin|DRUG: standard statin therapy|PROCEDURE: Coronary imaging follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antitumor Activity of Neoadjuvant Chemotherapy With or Without HCW9218 in Metastatic Advanced Stage Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin AUC 5 and paclitaxel|DRUG: HCW9218
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate on Intracortical Inhibition in Methamphetamine Abusers Attention Deficit Hyperactivity Disorder (ADHD)
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: methylphenidate tablets and Inter-stimulus Intervals (ISI)|OTHER: methylphenidate tablets and Inter-stimulus Intervals (ISI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Cancer (CCA)|Intrahepatic Cholangiocarcinoma|Hilar Cholangiocarcinoma|Distal Cholangiocarcinoma|Gall Bladder Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAC-cbt Group Therapy for Adults With ADHD
Status: UNKNOWN
Conditions: Psychotherapy
Interventions: BEHAVIORAL: MAC-cbt group treatment for adult ADHD|BEHAVIORAL: Jacobson
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision
Status: NOT_YET_RECRUITING
Conditions: Vulvar Squamous Cell Carcinoma
Interventions: PROCEDURE: Surgery|OTHER: Active Surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Nepafenac 0.1%|DRUG: Ketorolac 0.5%|OTHER: Placebo (sterile saline drops)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Optimisation Guided With Transcranial Doppler in Septic Shock
Status: UNKNOWN
Conditions: Trans Cranial Doppler Ultrasonography in Heamodynamic Optimisation in Septic Shock
Interventions: PROCEDURE: hemodynamic optimisation aiming to achieve normal cerebral perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraluminal Clarithromycin Powder Monotherapy for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Clarithromycin|DRUG: Amoxicillin, Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CurePPaC Study - Analysing Non-surgical Treatment Strategies to Cure Pes Planovalgus Associated Complaints
Status: TERMINATED
Conditions: Foot Injuries|Posterior Tibial Tendon Dysfunction
Interventions: DEVICE: Foot Orthoses Only|PROCEDURE: Foot Orthoses and Eccentric Exercise|DEVICE: Sham Foot Orthoses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimize RV Selective Site Pacing Clinical Trial
Status: TERMINATED
Conditions: Cardiac Pacing, Artificial|Cardiac Pacemaker, Artificial
Interventions: DEVICE: Medtronic Dual-Chamber Pacemaker|DEVICE: Medtronic SelectSecure 3830 Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of 8-week Incremental Elastic-Resistance Kick Training in Taekwondo Athlete's
Status: COMPLETED
Conditions: Strength|Performance
Interventions: OTHER: Elastic-Resistance Kick Training|OTHER: No Elastic-Resistance Kick Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Targeted Dose Finding of Canakinumab (ACZ885) for Management of Acute Flare in Refractory or Contraindicated Gout Patients
Status: COMPLETED
Conditions: Acute Gout
Interventions: DRUG: Canakinumab|DRUG: Canakinumab|DRUG: Canakinumab|DRUG: Canakinumab|DRUG: Canakinumab|DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness Training on Emotion Regulation and Social Cognition.
Status: UNKNOWN
Conditions: Stress, Psychological|Emotional Stress|Social Cognition|Mindfulness
Interventions: BEHAVIORAL: Mindfulness group|BEHAVIORAL: Reading group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Ketamine- dexmedetomidine|DRUG: Fentanyl- midazolam|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Molecular PD-L1 PET/CT Imaging With 89Zr-atezolizumab in Metastatic Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Metastatic Triple-Negative Breast Carcinoma
Interventions: DIAGNOSTIC_TEST: 89Zr-atezolizumab PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FDG PET-MRI for the Diagnosis of Spinal Cord Lesions
Status: COMPLETED
Conditions: Spinal Cord Neoplasm
Interventions: DRUG: Fludeoxyglucose F-18|DEVICE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Study to Compare the Safety and Immunogenicity of Fluviral® Made With New Versus Aged Bulk
Status: COMPLETED
Conditions: Influenza Vaccines
Interventions: BIOLOGICAL: Fluviral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Oseltamivir in High-Risk Patients Presenting to the Emergency Department With Influenza
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Oseltamivir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Analysis of the Peripheral Blood Mononuclear Cells of Patients With Ankylosing Spondylitis During Infliximab Treatment (Study P04465)(COMPLETED)
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Delorme Operation With or Without Postanal Repair in Treatment of Complete Rectal Prolapse
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: PROCEDURE: Group I: delorme operation only.|PROCEDURE: delorme operation with post anal repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrolizumab|DRUG: Infliximab|OTHER: Placebo (IV)|OTHER: Placebo (Injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|GBM
Interventions: DEVICE: SonoCloud-9 (SC9)|DRUG: Carboplatin|DRUG: Lomustine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acceptance and Commitment Therapy on Psychotic Severity
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychosis|Emotion Regulation|Recovery
Interventions: BEHAVIORAL: Acceptance and commitment therapy|COMBINATION_PRODUCT: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
Status: COMPLETED
Conditions: LGBTQ|Sexual Behavior
Interventions: BEHAVIORAL: Online EQuIP|BEHAVIORAL: Self-monitoring control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cyclosporine Adverse Outcomes in Steroid Dependent and Frequent Relapsing Nephrotic Syndrome in Children;Single Center Study
Status: NOT_YET_RECRUITING
Conditions: Steroid Dependent and Frequent Relapsing Nephrotic Syndrome
Interventions: OTHER: observation of the adverse outcomes of Cyclosporine in steroid dependent and frequent relapsing nephrotic syndrome in children
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Peripheral Magnetic Stimulation in Men With Lower Urinary Tract Symptoms
Status: UNKNOWN
Conditions: Bladder Hypersensitivity
Interventions: OTHER: Peripheral magnetic neuromodulation|DRUG: Taking drug Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol|PROCEDURE: Infraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Patients With Coronary Heart Disease After Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Heart Injuries
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9%NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Camel Milk on Insulin and Incretin Response
Status: UNKNOWN
Conditions: Insulin Sensitivity|Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: Camel milk|DIETARY_SUPPLEMENT: Cow milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
Status: TERMINATED
Conditions: Relapsed Solid Tumor|Refractory Solid Tumor|Relapsed Central Nervous System Tumor|Refractory Central Nervous System Tumor|Diffuse Intrinsic Pontine Glioma|High Grade Glioma
Interventions: DRUG: cemiplimab (monotherapy)|DRUG: cemiplimab (maintenance)|RADIATION: Conventional or hypofractionated|RADIATION: Re-irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy Versus Levofloxacin-based Therapy for Helicobacter Pylori Eradication in Mexico.
Status: COMPLETED
Conditions: Helicobacter Pylori Gastritis
Interventions: DRUG: CLA (Clarithro+Lanso+Amoxi)|DRUG: PLA (Panto+Levoflox+Azithro)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Myelin Disorders Biorepository Project
Status: RECRUITING
Conditions: Leukodystrophy|White Matter Disease|Leukoencephalopathies|4H Syndrome|Adrenoleukodystrophy|AMN|ALD|ALD Gene Mutation|ALD (Adrenoleukodystrophy)|X-linked Adrenoleukodystrophy|X-ALD|Adrenomyeloneuropathy|Aicardi Goutieres Syndrome|AGS|Alexander Disease|Alexanders Leukodystrophy|AxD|ADLD|Canavan Disease|CTX|Cerebrotendinous Xanthomatoses|Krabbe Disease|GALC Deficiency|Globoid Leukodystrophy|TUBB4A-Related Leukodystrophy|H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum|HBSL|HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity|LBSL|Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)|Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation|ALSP|CSF1R Gene Mutation|HCC - Hypomyelination and Congenital Cataract|MLC1|Megalencephalic Leukoencephalopathy With Subcortical Cysts|MLD|Metachromatic Leukodystrophy|PMD|Pelizaeus-Merzbacher Disease|PLP1 Null Syndrome|PLP1 Gene Duplication &#X7C; Blood or Tissue &#X7C; Mutations|Pelizaeus Merzbacher Like Disease|Peroxisomal Biogenesis Disorder|Zellweger Syndrome|Refsum Disease|Salla Disease|Sialic Storage Disease|Sjögren|Sjogren-Larsson Syndrome|Van Der Knapp Disease|Vanishing White Matter Disease|Charcot-Marie-Tooth|CMT|Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency|Allan-Herndon-Dudley Syndrome|Cadasil|Cockayne Syndrome|Multiple Sulfatase Deficiency|Gangliosidoses|GM2 Gangliosidosis|BPAN|Labrune Syndrome|LCC|Mucopolysaccharidoses|TBCK-Related Intellectual Disability Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Psorcast Mobile Study
Status: RECRUITING
Conditions: Psoriatic Arthritis|Psoriasis|Psoriatic Conditions|Dermatologic Disease|Rheumatologic Disease|Psoriatic Nail|Plaque Psoriasis|Joint Pain|Dactylitis
Interventions: BEHAVIORAL: Participant self-assessment surveys|BEHAVIORAL: Psoriasis Draw|BEHAVIORAL: Psoriasis Area Photo|BEHAVIORAL: Finger and Toe Photos|BEHAVIORAL: Digital Jar Open|BEHAVIORAL: 30 Second Walk|OTHER: Psorcast mobile application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Propranolol and Botulinum Toxin for Essential Vocal Tremor
Status: COMPLETED
Conditions: Essential Vocal Tremor|Essential Voice Tremor|Essential Tremor|Voice Tremor|Vocal Tremor
Interventions: DRUG: Propranolol|PROCEDURE: Botulinum Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation for Children Suffering From Biliary Atresia
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education
Status: COMPLETED
Conditions: Fertility Issues|Breast Cancer|Education
Interventions: OTHER: Naturalistic Decision-Making Model-based Oncofertility Care Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer
Status: RECRUITING
Conditions: Proximal Gastric Adenocarcinoma|Gastric Cancer|Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxic Changes in Hepatocellular Carcinoma (HCC) Following Trans Arterial Chemo Embolization and Stereotactic Radiation: Fluorine18 (18F) Fluoromisonidazole (FMISO) Imaging
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: FMISO|DRUG: FMISO|DRUG: FMISO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Non-invasive Neurostimulation (Transcutaneous Vagus Nerve Stimulation) on 1. the Noradrenergic Release in the Brain and 2. a Neuropsychological Memory Task
Status: COMPLETED
Conditions: Epilepsy|Cognitive Decline
Interventions: DEVICE: Transcutaneous vagus nerve stimulation (Nemos®, Cerbomed GmbH)|DEVICE: Sham stimulation (Nemos®, Cerbomed GmbH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimized Acupuncture Treatment for Female Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Sacral acupoints acupuncture|DEVICE: Abdominal acupoints acupuncture|DEVICE: Alternating acupoints acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Age on the Success of DPC Using Bio-ceramic Materials in Cariously Exposed Teeth With Reversible Pulpitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulpitis Reversible
Interventions: PROCEDURE: DPC with MTA in AGEI|PROCEDURE: DPC with BD in AGEI|PROCEDURE: DPC with MTA in AGEII|PROCEDURE: DPC with BD in AGEII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobacco Education and Lung Health Study (TEAL)
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention|BEHAVIORAL: E-Referral to the Tobacco Quitline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BMS-986104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IntelliCycleTM 2.0 Improved Patient-ventilator Asynchrony During PSV
Status: COMPLETED
Conditions: Automatic Adjustmen of Inspiratory Triger and Cycling-off
Interventions: DEVICE: automatic adjustmen of inspiratory triger and cycling-off based on waveform and PSV with fixed Esence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AMG 162 (Denosumab) Phase 3 Study (DESIRABLE Study) in Participants With Rheumatoid Arthritis on Disease-modifying Antirheumatic Drugs (DMARDs) Treatment
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: denosumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Resolution Imaging of Cerebral Vasculature by Functional Micro-Doppler Sonography During Brain Surgery
Status: TERMINATED
Conditions: Partial Drug-resistant Epilepsy
Interventions: DEVICE: Functional micro-Doppler Sonography (fmDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Immunogenicity and Safety of GSK's Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: BIOLOGICAL: GSK's investigational non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) multi-antigen vaccine (GSK3277511A) adjuvanted with AS01E|BIOLOGICAL: Shingrix GSK's lyophilized formulation of the herpes zoster (HZ) vaccine (GSK1437173A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: DRUG: Cixutumumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Responsiveness Prediction During Prone Position
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DIAGNOSTIC_TEST: Trendelenburg maneuver|DIAGNOSTIC_TEST: End-expiratory occlusion test (EE OCC)|DIAGNOSTIC_TEST: End-expiratory and end-inspiratory occlusion test (EI OCC)|DIAGNOSTIC_TEST: Tidal volume challenge|DIAGNOSTIC_TEST: Fluid bolus (reference diagnostic method)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Low-Dose Taxotere® (Docetaxel) With Concurrent Radiotherapy For Localized, Inoperable Carcinoma Of The Uterine Cervix
Status: COMPLETED
Conditions: Cervix Neoplasm
Interventions: DRUG: docetaxel|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Adaptive Interventions for Suicidal College Students Seeking Treatment - SMART
Status: COMPLETED
Conditions: Suicide
Interventions: BEHAVIORAL: Stage 1 Treatment as usual (TAU)|BEHAVIORAL: Stage 1 CAMS|BEHAVIORAL: Stage 2 CAMS|BEHAVIORAL: Stage 2 Dialectical Behavioral Therapy (DBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism
Status: RECRUITING
Conditions: Aldosterone-Producing Adenoma
Interventions: DIAGNOSTIC_TEST: [18F]AlF-NOTA-pentixather PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Digital Peer Navigation for Adolescents and Young Adults With Cancer
Status: NOT_YET_RECRUITING
Conditions: Lymphoma|Breast Cancer|Testicular Cancer|Sarcoma
Interventions: BEHAVIORAL: Digital Peer Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents
Status: COMPLETED
Conditions: Advanced Cancer|Colorectal Cancer|Mantle Cell Lymphoma
Interventions: DRUG: Ramucirumab|DRUG: Merestinib|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of a Sustained Release Methylphenidate in the Treatment of Fatigue in Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer|Fatigue|Gastrointestinal Cancer
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Isopropyl Alcohol vs Ondansetron for Nausea in the Emergency Department
Status: COMPLETED
Conditions: Nausea
Interventions: DRUG: Inhaled isopropyl alcohol|DRUG: Oral ondansetron|DRUG: Inhaled normal saline|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Yoga Exercises and Callisthenic Exercises on the Quality of Life in Healthy Individuals
Status: COMPLETED
Conditions: Quality of Life|Exercise
Interventions: OTHER: Yoga Exercise|OTHER: Calisthenic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Whole-body Diffusion-weighted Magnetic Resonance Imaging for Staging and Treatment Prediction of Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Hodgkin Lymphoma|Non-Hodgkin Lymphoma (Follicular, Diffuse B-cel Lymphoma, PTLD and Mantle Cel Lymphoma)
Interventions: OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of G-CSF (Colony Stimulating Factor) in Patients With Chronic Chagas Cardiomyopathy
Status: COMPLETED
Conditions: Chronic Chagasic Myocarditis
Interventions: DRUG: Treatment with G-CSF (Granulocyte colony stimulating factor)|DRUG: Placebo saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Social Skills Training and Standard Treatment Versus Standard Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Social skills training, parental tr. and standard tr.|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prasugrel on Bronchial Hyperreactivity and on Markers of Inflammation in Patients With Chronic Asthma
Status: COMPLETED
Conditions: Chronic Asthma
Interventions: DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Occupational Therapy Intervention in Hemodialysis Patients
Status: UNKNOWN
Conditions: Quality of Life
Interventions: BEHAVIORAL: Awareness Training and Person-Centered Occupational Therapy Intervention|BEHAVIORAL: Awareness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Milademetan|DRUG: AZA|DRUG: Milademetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: " Treating MS Patients With Lower Extremity Spasticity Using Dysport"
Status: UNKNOWN
Conditions: Multiple Sclerosis|Spasticity, Muscle
Interventions: BIOLOGICAL: Abobotulinumtoxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Harm Reduction Intervention Among Female Sex Workers in Mombasa, Kenya
Status: COMPLETED
Conditions: Alcohol Use and STI/HIV Infections, Domestic Violence
Interventions: BEHAVIORAL: Behavioral Intervention for Alcohol Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Acute Hospitalisation and Resistance Training on Muscle Architecture and Physical Performance in Older Adults
Status: RECRUITING
Conditions: Sarcopenia|Functional Decline|Muscle Architecture|Gait Speed|Ultrasound|Physical Performance|Resistance Training|Hospitalisation|Acutely Ill|Older Adults
Interventions: OTHER: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Physical Functioning in Patients With COPD During Therapy With a Combination Inhalation Therapy
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Spiriva® Respimat®|DRUG: Striverdi® Respimat®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p