pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rectal Indomethacin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High Risk Patients
Status: TERMINATED
Conditions: Post-ERCP Pancreatitis
Interventions: DRUG: Indomethacin|OTHER: Placebo suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acetaminophen Transfer Across the Placenta and the Assessment of Fetal Well-being
Status: COMPLETED
Conditions: Fetal Testing|Transplacental Transfer of Acetaminophen
Interventions: DRUG: Arm 1 (20 patients)|DRUG: Arm 2 (34 patients)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Persistent Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Beclomethasone 800 µg per day|DRUG: Placebo|DRUG: Beclomethasone 400 µg per day|DRUG: Beclomethasone 640 µg per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride, Rituximab, Etoposide, and Carboplatin in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma or Hodgkin Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma
Interventions: DRUG: Bendamustine Hydrochloride|DRUG: Carboplatin|BIOLOGICAL: Rituximab|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Surgical PDA Ligation and Neonatal Outcomes
Status: COMPLETED
Conditions: Patent Ductus Arteriosus|Patent Ductus Arteriosus - Delayed Closure|Patent Ductus Arteriosus After Premature Birth
Interventions: OTHER: PDA ligation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care (Pegylated-interferon Alpha-2b and Ribavirin) in Japanese Patients
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: BMS-790052|DRUG: BMS-790052|DRUG: Placebo|DRUG: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Ibrutinib (RI) Versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström's Macroglobulinaemia
Status: RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Dexamethasone, cyclophosphamide, rituximab|DRUG: Rituximab, ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety, Tolerability and Pharmacodynamics After Administration of One Dose of AZD8601 to Male Patients With Type II Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Male Subjects With Type II Diabetes (T2DM)
Interventions: DRUG: AZD8601+Placebo (SAD)|DRUG: AZD8601+Placebo|DRUG: Placebo+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S0341: Erlotinib in Treating Patients With Advanced Primary Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Large Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoprevention of Colorectal Adenomas
Status: TERMINATED
Conditions: Adenomatous Polyps
Interventions: DRUG: 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol)|DRUG: 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3)|DRUG: placebo to 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol)|DRUG: placebo to 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3)|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Investigational Positron Emission Tomography and Post-Processing Procedures Performed as Add-ons to Standard of Care Imaging
Status: ACTIVE_NOT_RECRUITING
Conditions: PET Imaging
Interventions: DIAGNOSTIC_TEST: PET scan|OTHER: Retrospective data analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploring the Relationship Between ICOPE Framework and Frailty Among Community-dwelling Elderly Individuals
Status: COMPLETED
Conditions: Community-dwelling Elderly
Interventions: BEHAVIORAL: Montreal Cognitive Assessment (MoCA)|BEHAVIORAL: Chinese ICOPE screening tool (self-administration and interview versions)|BEHAVIORAL: Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Satiety Effect of a Very Low Energy Foam With Normal Energy Foams
Status: COMPLETED
Conditions: Satiety|Appetite
Interventions: DIETARY_SUPPLEMENT: Very low energy aerated beverage|DIETARY_SUPPLEMENT: Normal energy aerated beverage 1|DIETARY_SUPPLEMENT: Normal energy aerated beverage 2|DIETARY_SUPPLEMENT: Normal energy aerated beverage 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuromuscular Electrical Stimulation in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke|Neuromuscular Electrical Stimulation|Exercise
Interventions: DEVICE: NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections
Status: COMPLETED
Conditions: Staphylococcal Infection|Abscess|Staphylococcal Skin Infection|Folliculitis
Interventions: DRUG: clindamycin|DRUG: cephalexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Status: RECRUITING
Conditions: Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Interventions: PROCEDURE: Minced skin grafts for donor site
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Norgestrel 75 mcg on Cervical Mucus and Ovarian Activity During Perfect Use, After One Delayed Intake and After a Missed Pill
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Norgestrel 0.075 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Acute Myocardial Infarction|Unstable Angina (Intermediate Coronary Syndrome)
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pharmacokinetics and Safety of HS632 and Xolair® With a Single Injection
Status: UNKNOWN
Conditions: Similarity of Pharmacokinetics and Safety
Interventions: DRUG: HS632|DRUG: Omalizumab (Xolair®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation
Status: UNKNOWN
Conditions: Chronic Myeloproliferative Disorders|Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Oral Complications|Ovarian Cancer|Pain|Sarcoma
Interventions: PROCEDURE: management of therapy complications|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Efficacy, and Pharmacokinetics of Multiple Doses of ION224
Status: COMPLETED
Conditions: Steatohepatitis, Nonalcoholic
Interventions: DRUG: ION224|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Use of a Brain-computer Interface Based on TMS Neurofeedback for Upper Limb Stroke Rehabilitation
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Stroke|Stroke Rehabilitation|Upper Extremity Paresis
Interventions: OTHER: Transcranial Magnetic Simulation with Pseudofeedback|OTHER: Transcranial Magnetic Simulation with Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Anfibatide Treatment in STEMI Patients
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: DRUG: placebo|DRUG: Anfibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief in HSG in a Tertiary Hospital in Kano
Status: UNKNOWN
Conditions: Female Infertility of Tubal Origin
Interventions: DRUG: Intracervical lidocaine|DRUG: Intramuscular Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Functional Magnetic Resonance Imaging (fMRI) Study in Overweight and Obese Men (0000-103)
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: Comparator: sibutramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Carboplatin|DRUG: Epirubicin|BIOLOGICAL: Trastuzumab|DRUG: Everolimus|DRUG: Gemcitabine|BIOLOGICAL: Robatumumab|BIOLOGICAL: Cetuximab|DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: 5-FU|DRUG: Erlotinib|DRUG: Irinotecan|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation
Status: COMPLETED
Conditions: Loss of Chromosome 17p|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma|Richter Syndrome
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theta-Burst Neuromodulation for PTSD
Status: COMPLETED
Conditions: Chronic Post-Traumatic Stress Disorder
Interventions: DEVICE: Theta burst stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Safety, Tolerability and Prelimenary Efficacy of LNA043 in Patients Undergoing Autologous Chondrocyte Implantation
Status: TERMINATED
Conditions: Knee Cartilage Lesion
Interventions: BIOLOGICAL: LNA043|BIOLOGICAL: placebo to LNA043
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cyclosporine Ophthalmic Soution Group and Cyclosporine Ophthalmic Suspension Group
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cyclosporine ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CvC-SAD (Clinician vs Coach)Self-help Versions in a RCT
Status: NOT_YET_RECRUITING
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: iCBT(C&W) for SAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ECG Signal Collection From Long QT Syndrome, Wide QRS Complexes, Heart Failure, and Cardiac Resynchronization Patients
Status: COMPLETED
Conditions: Long QT Syndrome|Wide QRS Complexes|Heart Failure|Cardiac Resynchronisation
Interventions: DEVICE: subcutaneous ICD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Regadenoson|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Performance of a Glass-ionomer Restorative System: A 6-year Evaluation
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: EQUIA|OTHER: Gradia Direct Posterior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Applying Mobile Persuasive Technologies to Increase Physical Activity in Women
Status: COMPLETED
Conditions: Sedentary Lifestyle|Physical Activity
Interventions: BEHAVIORAL: Mobile phone based physical activity intervention with maintenance plus|BEHAVIORAL: Mobile phone based physical activity intervention with maintenance regular|BEHAVIORAL: Control (pedometer only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Omicron BA.4/5-Delta Strain Recombinant Novel Coronavirus Protein Vaccine (CHO Cells)
Status: NOT_YET_RECRUITING
Conditions: Coronavirus
Interventions: BIOLOGICAL: Omicron BA.4/5-Delta strain recombinant novel coronavirus protein vaccine (CHO cells)|BIOLOGICAL: Recombinant novel coronavirus protein vaccine (CHO cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel
Status: COMPLETED
Conditions: Acute Pain|Breast Carcinoma|Peripheral Neuropathy
Interventions: DRUG: Minocycline Hydrochloride|OTHER: Placebo|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study to Investigate Biomarkers in Anterior Cruciate Ligament (ACL) Patients and Healthy Controls
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: Surgeons knowledge of pre-operative PBIs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Different Doses of Tyrosine Adsorbed Tree Pollen Allergoid With Monophosphoryl Lipid A (MPL) in Patients Sensitized to Tree Pollen
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Tree MATA MPL - Therapeutic Regimen|BIOLOGICAL: Tree MATA MPL - Intermediate dose|BIOLOGICAL: Tree MATA MPL - Low dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome
Status: RECRUITING
Conditions: Dravet Syndrome
Interventions: DRUG: ETX101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of the Neuroimaging Biomarker-based Prediction Model of Anxiety-related Disorders: Effect of Mindfulness-based Cognitive Therapy Using Neuroscience on the Brain
Status: NOT_YET_RECRUITING
Conditions: Anxiety Depression
Interventions: BEHAVIORAL: Mindfulness-based cognitive therapy using neuroscience (NMBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Infarction Triggers and Onset in Jordan Study 2
Status: TERMINATED
Conditions: Triggers of Acute Myocardial Infarction|Time of Onset of Acute Myocardial Infarction|Long-term Prognosis After Acute Myocardial Infarction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Liver Metastases From Colorectal Cancer After Conventional Chemotherapy Failure
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: oxaliplatin|DRUG: raltitrexed|DRUG: other intravenous chemotherapy drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stopping Pneumonia Antibiotherapy Regimen Early
Status: NOT_YET_RECRUITING
Conditions: Community-acquired Pneumonia|Child, Only
Interventions: DRUG: Quick response: Amoxicillin for 3 days|DRUG: Delayed response: Amoxicillin for 5 days|DRUG: Quick response: Amoxicillin for 5 days|DRUG: Delayed response: Amoxicillin for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Closure in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic KIDNEY Disease
Status: RECRUITING
Conditions: Non-valvular Atrial Fibrillation (NVAF): Paroxysmal, Persistent, Permanent
Interventions: OTHER: Left Atrial Appendage closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Status: RECRUITING
Conditions: Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
Interventions: DEVICE: Magnetometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Allogeneic CD19 CAR-T Cells for the Treatment of Relapsed/Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: BIOLOGICAL: Allogeneic CD19 CR-T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
Status: COMPLETED
Conditions: Perimenopausal Bone Loss
Interventions: DRUG: Natto capsules (food suppl.) cont. 360 microg. vit K2/day|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: HER2 Gene Mutation
Interventions: COMBINATION_PRODUCT: Injection of IAH0968 + CAPEOX|COMBINATION_PRODUCT: PLACEBO+CAPEOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostaglandin E2 in Migraine Suffers Without Aura.
Status: COMPLETED
Conditions: "Migraine-like" Headache
Interventions: DRUG: dinoprostone|DRUG: isoton sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Big Squeeze (Lessening the Big Squeeze: The Effect of the Trunk Release on Interface Pressures of Individuals Seated in a High Fowler's Positions)
Status: COMPLETED
Conditions: Elderly
Interventions: PROCEDURE: The Big Squeeze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Study the Effects of a Fixed Dose Combination of Diclofenac and Eperisone Hydrochloride With Plain Eperisone Hydrochloride in Patients With Low Back Pain
Status: COMPLETED
Conditions: Acute Musculoskeletal Spasm Due to Low Back Pain
Interventions: DRUG: Eperisone hydrochloride and Diclofenac sodium|DRUG: Eperisone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Camouflaged Syringe vs Conventional Syringe
Status: COMPLETED
Conditions: Dental Anxiety|Behavior
Interventions: DEVICE: Conventional Syringe|DEVICE: Camouflage Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-BAFF CAR-T Cells Therapy for Patients With Relapsed / Refractory B-cell ALL and B-cell NHL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia,B-Cell|Non-hodgkin Lymphoma,B Cell
Interventions: BIOLOGICAL: CD19-BAFF Targeted CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TGRX-678 Chinese Phase I in Chronic Myelogenous Leukemia (CML) Patients
Status: RECRUITING
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: TGRX-678
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Class II Malocclusion Combined With Low-level Laser
Status: COMPLETED
Conditions: Malocclusion, Angle Class II
Interventions: DEVICE: Twin-block appliance|OTHER: Low level laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI
Status: RECRUITING
Conditions: Left Bundle-Branch Block|Aortic Valve Stenosis
Interventions: DEVICE: Pacemaker implant|DEVICE: Transcutaneous cardiac monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
Status: RECRUITING
Conditions: Fibrinogen|Spine Deformity|Coagulopathy, Consumption|Bleeding
Interventions: DRUG: Fibrinogen Concentrate Human
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Twelve Month Follow-Up of CP0108
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aminolevulinic Acid (ALA)|DRUG: Topical Solution Vehicle|DEVICE: BLU-U Blue Light Photodynamic Therapy Illuminator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Biliary Tract Cancer
Status: COMPLETED
Conditions: Biliary Tract Cancer|Metastatic Cancer|Advanced Cancer|Gallbladder Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrigenomics, Overweight/Obesity and Weight Management Trial (NOW Trial)
Status: UNKNOWN
Conditions: Transplant-Related Disorder|Overweight and Obesity
Interventions: GENETIC: Personalized Nutrigenomics Testing (PNT)|OTHER: Standard Nutrition Intervention (SNI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Dose on the Pharmacokinetics of OROS Hydromorphone Under Fasted Conditions in Healthy Taiwanese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A: Hydromorphone 8 mg|DRUG: Treatment B: Hydromorphone 16 mg|DRUG: Treatment C: Hydromorphone 32 mg|DRUG: Treatment D: Hydromorphone 64 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Reduction of Preoperative Radiotherapy in Myxoid Liposarcomas
Status: UNKNOWN
Conditions: Myxoid Liposarcoma of Soft Tissue
Interventions: RADIATION: dose reduction of preoperative radiotherapy in MLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EValuation of radIOLigand Treatment in mEn With Metastatic Castration-resistant Prostate Cancer With [161Tb]Tb-PSMA-I&T
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: [ 161 Tb]Tb PSMA I&T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone on Insulin Sensitivity in Healthy Overweight and Obese Males (MK-0000-170)
Status: COMPLETED
Conditions: Healthy|Overweight|Obesity
Interventions: DRUG: Placebo|DRUG: Comparator: Pioglitazone|DRUG: Comparator: Hyperinsulinemic Euglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate GBT021601 in Single and Multiple Doses in Healthy Participants
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: GBT021601
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CTX-009 With Gemcitabine, Cisplatin, and Durvalumab as First-line Therapy in Patients With Unresectable or Metastatic Biliary Tract Cancers
Status: NOT_YET_RECRUITING
Conditions: Metastatic Biliary Tract Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Durvalumab|DRUG: CTX-009
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic for Vaginal Candidiasis in Pregnant Women
Status: COMPLETED
Conditions: Vaginal Diseases
Interventions: DIETARY_SUPPLEMENT: STP4 (product with probiotics)|DIETARY_SUPPLEMENT: Placebo (product without probiotics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2A Study of ALXN1007 in Participants With Newly Diagnosed Acute Lower Gastrointestinal Graft-Versus-Host Disease
Status: TERMINATED
Conditions: Acute Graft-Versus-Host Disease|GIGVHD
Interventions: BIOLOGICAL: ALXN1007 10 mg/kg once weekly|BIOLOGICAL: ALXN1007 20 mg/kg once weekly|BIOLOGICAL: ALXN1007 20 mg/kg twice weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasm Metastasis
Interventions: DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Trastuzumab Emtansine|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Molecular, Genomic, Morphology and Environmental Features to Improve Precision Diagnosis and Treatment in Interstitial Lung Diseases (PRECISION-ILD)
Status: RECRUITING
Conditions: Interstitial Lung Disease|Interstitial Fibrosis
Interventions: OTHER: Observational register
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Fluticasone/Salmeterol Combination on Exertional Breathlessness in Patients With Mild COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: fluticasone/salmeterol combination|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cilostazol and Endothelial Progenitor Cell
Status: UNKNOWN
Conditions: Myocardial Infarction, Acute
Interventions: DRUG: Cilostazol Tablets|DRUG: placebo|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HELicobacter Pylori Screening in Patients With Acute Myocardial Infarction Pilot Study
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction|NSTEMI - Non-ST Segment Elevation MI
Interventions: DIAGNOSTIC_TEST: Helicobacter Pylori screening by UBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study: Higher Density Ulthera® System Treatment With Vectoring for Treatment of the Face and Neck
Status: COMPLETED
Conditions: Skin Laxity
Interventions: DEVICE: Ulthera System Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Cost Analysis of Steroids in Treatment of Otitis Media With Effusion
Status: COMPLETED
Conditions: Otitis Media With Effusion
Interventions: DRUG: Mometasone 50 Mcg/Inh Nasal Spray|DRUG: Antibiotics + Antihistamine (levocetirizine) + Nasal decongestants (Oxymetazoline 0.025%)|DRUG: Steroid Drug (prednisolone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Bowel Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noctura400 Treatment for Diabetic Retinopathy (CANDLE)
Status: TERMINATED
Conditions: Diabetic Macular Oedema
Interventions: DEVICE: Noctura 400 Eye Mask|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NORCCAP: Norwegian Colorectal Cancer Prevention Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Adenoma
Interventions: PROCEDURE: A 1 Intervention arm Flex Sig|PROCEDURE: A 2 Intervention arm Flex Sig + iFOBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wall Strain Index Ratio as a Biomarker for Mechanical Complication of Hemorrhagic Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Hemorrhagic Myocardial Infarction|Myocardial Stunning|Myocardial Hemorrhage|Myocardial Reperfusion Injury|Myocardial Rupture (Post Infarct)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Status: RECRUITING
Conditions: Type2diabetes|Heart Failure With Preserved Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Potato Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proof of Concept Study to Eval MetriDx Lab-developed Test to Identify Endometriosis-specific Bio Markers
Status: RECRUITING
Conditions: Endometriosis|Diagnosis
Interventions: DIAGNOSTIC_TEST: MetriDx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevalence and Factors Associated With the Occurrence of Depression Six Months After an Endovascular Treatment of Intracranial Aneurysm
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: OTHER: questionnaires assessing the state of fatigue, depression and anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Age, Physical Fitness and a Single Bout of Aerobic Exercise on Motor and Cognitive Functions
Status: UNKNOWN
Conditions: Physical Activity|Age-related Cognitive Decline
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Watching television
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial
Status: COMPLETED
Conditions: Coronary Occlusions
Interventions: DEVICE: Cypher sirolimus eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Effect Of Spinal Orthosis On Tactile Sense And Balance In Individuals With Lumbal Curve And Adolescent Idiopathic Scoliosis
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Spinal Orthosis Application
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This Study in Healthy Men Tests How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 705564 Affects the Way the Body Breaks Down Midazolam
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 705564|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Advanced Peritoneal Malignant Mesothelioma|Advanced Pleural Malignant Mesothelioma|Recurrent Peritoneal Malignant Mesothelioma|Recurrent Pleural Malignant Mesothelioma|Refractory Malignant Solid Neoplasm|Unresectable Solid Neoplasm
Interventions: DRUG: Cisplatin|DRUG: Methoxyamine|DRUG: Pemetrexed Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 7 Days of Letrozole Pretreatment Combined With Misoprostol on the Placental and Decidual Tissues
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Letrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators.
Status: COMPLETED
Conditions: ICD|Sudden Cardiac Death|Ventricular Fibrillation|Atrial Fibrillation|Ventricular Tachycardia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study 3 of Outpatient Control-to-Range: Safety and Efficacy With Day-and-Night In-Home Use
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Closed-Loop Control System|DEVICE: Sensor-Augmented Pump (SAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Determine the Role of Adding Campath-1H or ATG Given In-vivo in Addition to Fludarabine and Low Dose Busulfex on Outcome in Patients Treated With Reduced Intensity Conditioning
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Campath-1H /ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Glimepiride|DRUG: Canagliflozin (JNJ-28431754)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Neoadjuvant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Supracervical Hysterectomy Versus Total Laparoscopic Hysterectomy
Status: WITHDRAWN
Conditions: Gynecologic Diseases
Interventions: PROCEDURE: Laparoscopic supracervical hysterectomy|PROCEDURE: Total laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Inactivated Poliovirus Vaccine Given at an Earlier Schedule With Shorter Intervals
Status: COMPLETED
Conditions: Level of Immunity Against Poliovirus Infection
Interventions: BIOLOGICAL: Inactivated Polio Vaccine given at an accelerated schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer
Status: UNKNOWN
Conditions: Advanced Esophageal Squamous Cell Cancer
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histological Modifications of Postmenopausal Vaginal Mucosa After Repeated Carbon Dioxide (CO2) Laser Treatment
Status: COMPLETED
Conditions: Vaginal Atrophy|Breast Cancer Female|Dyspareunia
Interventions: DEVICE: SmartXide 2 V 2 LR, MonaLisa Touch, DEKA, Florence, Italy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for the Safety and Efficacy of CD-801 in Patients With Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: CD-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Use of Low-dose Sugammadex Plus Neostigmine Administered for Reversal of Rocuronium
Status: UNKNOWN
Conditions: Incidence of Postoperative Residual Curarization
Interventions: DRUG: Sugammadex|DRUG: neostigmine+atropine|DRUG: neostigmine+atropine+sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)
Status: RECRUITING
Conditions: Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia|ph+ Acute Lymphoblastic Leukemia
Interventions: DRUG: Inotuzumab ozogamicin|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Methotrexate|DRUG: Vincristine|DRUG: Ponatinib|DRUG: Methotrexate for Injection|PROCEDURE: Allogenic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT/MR-US Automatic Fusion System in Pre-procedure Planning for Radiofrequency Ablation
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: automatic CT/MRI-US fusion system guided radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Transcutaneous Electrical Stimulation in Sleep Apnoea
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea
Interventions: DEVICE: Transcutaneous electrical stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Troponin I and NT Pro-BNP in Lung Resection
Status: UNKNOWN
Conditions: Cardiac Ischemia|Thoracic Cancer|Complication,Postoperative
Interventions: DIAGNOSTIC_TEST: serum high-sensitivity Troponin I (TnI) and NT-Pro-Brain Natriuretic Peptide (NT-proBNP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides
Status: COMPLETED
Conditions: Rhytides
Interventions: DRUG: PrabotulinumtoxinA-Xvfs|DRUG: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome
Status: RECRUITING
Conditions: Recurrent Transformed Chronic Lymphocytic Leukemia|Refractory Transformed Chronic Lymphocytic Leukemia|Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma|Refractory Transformed B-cell Non-Hodgkin Lymphoma|Refractory Transformed
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Leukapheresis|BIOLOGICAL: Lisocabtagene Maraleucel|PROCEDURE: Lymph Node Biopsy|PROCEDURE: Positron Emission Tomography|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HEPLISAV™ Hepatitis B Virus Vaccine Compared With Engerix-B® Vaccine
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HEPLISAV and/or Placebo|BIOLOGICAL: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: FOLFOXIRI Plus Panitumumab In Kras and Braf Wild-Type Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colo-rectal Cancer
Interventions: DRUG: FOLFOXIRI + Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella
Status: COMPLETED
Conditions: Growth Hormone|Elderly
Interventions: DRUG: Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Alternative Approach to Improve Hyperglycemia Among Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Bitter melon juice (100 ml)|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT