pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treatment of Elderly Chinese Acute Myeloid Leukemia Patients Aged 65 to 75 Years Old
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CAG regimen (Aclacinomycin, cytarabine, with/w/o G-CSF)|DRUG: low dose cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Social Skills Training in Visually Impaired Adolescents
Status: COMPLETED
Conditions: Visual Disorder|Young Adult|Blindness|Blindness and Low Vision|Blindness Congenital
Interventions: BEHAVIORAL: Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Q-POC SARS-CoV-2 Assay COVID-19 Clinical Evaluation
Status: COMPLETED
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: RT-PCR Test|DIAGNOSTIC_TEST: Real-time PCR Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease
Status: RECRUITING
Conditions: Acute Stroke|Dual Antiplatelet Therapy|Statin
Interventions: DRUG: Clopidogrel|DRUG: Aspirin|DRUG: Atorvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET-CT-based Study of Central Mechanisms of Cortical Metabolism in 18F-FDG and 18F-AV1451 Age-related Deafness
Status: RECRUITING
Conditions: Age-related Hearing Loss|PET-CT
Interventions: DEVICE: hearing aids|OTHER: without hearing intervention|OTHER: healthy control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults
Status: COMPLETED
Conditions: Pulmonary Disease|Tuberculosis, Pulmonary|Tuberculosis|Multi Drug Resistant Tuberculosis|Drug Sensitive Tuberculosis|Drug-resistant Tuberculosis|Mycobacterium Tuberculosis Infection
Interventions: DRUG: TBAJ-876|DRUG: TBAJ-876|DRUG: Midazolam|DRUG: Digoxin|DRUG: TLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
Status: ACTIVE_NOT_RECRUITING
Conditions: Macular Edema|Radiation Retinopathy|Branch Retinal Vein Occlusion|Epiretinal Membrane|Central Serous Retinopathy With Pit of Optic Disc|Commotio Retinae|Vitritis
Interventions: DRUG: Episcleral Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
Status: RECRUITING
Conditions: Tonsillitis|Tonsillectomy
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of Upper Extremity Isokinetic Strengthening in Post-stroke Hemiplegia
Status: COMPLETED
Conditions: Stroke Rehabilitation|Hemiplegia
Interventions: DEVICE: isokinetic strengthening|OTHER: exercise band strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Recruitment Maneuver in Patients Undergoing Robotic Assisted Radical Prostatectomy
Status: COMPLETED
Conditions: Effects of Recruitment Maneuver During Intraoperative and Postoperative Period
Interventions: PROCEDURE: recruitment maneuver(RM) and positive end expiratory pressure(PEEP) or PEEP only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib Treatment
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Erlotinib|DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Comparing Raltegravir to a Protease Inhibitor in Treatment-naïve, HIV/Hepatitis C Drug Users
Status: UNKNOWN
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Raltegravir|DRUG: Atazanavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma
Status: UNKNOWN
Conditions: Bladder Cancer Stage IV
Interventions: DRUG: Chidamide with tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation
Status: TERMINATED
Conditions: Ventricular Tachycardia|Cardiomyopathy
Interventions: PROCEDURE: Ablation of ventricular arrhythmias|PROCEDURE: Ablation of ventricular arrhythmias + renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Nitric Oxide|DEVICE: Nasal spray with isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antihypertensive Efficacy and Tolerability and Determine the Adequate Antihypertensive Dosage of Fimasartan in Mild to Moderate Essential Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imagine(fMRI)Navigation in Intracranial Arteriovenous Malformation Surgery
Status: UNKNOWN
Conditions: Intracranial Arteriovenous Malformations
Interventions: PROCEDURE: fMRI Navigation AVM resection|PROCEDURE: conventional resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Awakening Capability by a Vibrating Bracelet (BRASSARD)
Status: COMPLETED
Conditions: Congenital Central Hypoventilation Syndrome|Patients With Nocturnal Ventilatory Assistance|Healthy Volunteers
Interventions: OTHER: Vibrating bracelet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Acupuncture in Post-Mastectomy Patients With Tissue Expanders
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: OTHER: Immediate Post Operative Acupuncture Treatment|OTHER: No Acupuncture Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study DHP107, a Novel Oral Paclitaxel Formulation, in Patients With Advanced Solid Tumours or Gastric Cancer
Status: COMPLETED
Conditions: Solid Tumor|Stage IV Gastric Cancer
Interventions: DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl as an Adjuvant to Peribulbar Block in Buckle or Squint Surgeries
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Lymphoblastic Leukemia, Acute
Interventions: DRUG: Prednisone, Dexamethasone, Vincristine, Daunorubicin|DRUG: Doxorubicin, L-asparaginase, PEG-L-asparaginase, Erwinia asparaginase|DRUG: Methotrexate, Cyclophosphamide, Cytarabine, Etoposide|DRUG: Mercaptopurine, Imatinib|PROCEDURE: chemotherapy, intrathecal chemotherapy|PROCEDURE: steroid therapy, hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Atrial Fibrillation in the Wait-Time Prior to Seeing a Cardiologist
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Atrial Fibrillation Paroxysmal|Arrhythmias, Cardiac|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Holter monitoring|DIAGNOSTIC_TEST: Kardia/AliveCor monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S-1 and Cisplatin in Treating Patients Who Are Undergoing Surgery for Stage III Stomach Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: tegafur-gimeracil-oteracil potassium|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Melflufen|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Tolerability Study of Topiramate in Participants With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Topiramate Standard|DRUG: Topiramate Slow|DRUG: Propranolol booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of the Pleth Variability Index to Predict Fluid Responsiveness in Liver Transplantation
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DEVICE: PVI-guided fluid management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exertional Exhaustion in Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome
Interventions: PROCEDURE: Submaximal bicycle exercise stress test on Days 1 and 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Management of Patients Surgically Treated for Chronic Pelvic Pain by Minimally Invasive Surgery
Status: UNKNOWN
Conditions: Pelvic Pain
Interventions: PROCEDURE: Minimally Invasive Gynecologic Surgery|PROCEDURE: osteopathic manipulative treatment|DRUG: Pain killer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bacterial Microleakage and Bone Loss in Internal Connection Dental Implants Based on the Type of Abutment Used in Zirconia Partial Fixed Prosthesis: in Vivo Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Transepithelial abutment group|DEVICE: Direct to implant group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Prolonging the Time of Progesterone Supplementation to Improve the Pregnancy Outcome of Single Day 6 Blastocyst Transfer of Freeze-thaw Cycle
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: progesterone|DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Period and Long-term Efficacy of Functional Electrical Stimulation (FES) on Sleep Bruxism
Status: TERMINATED
Conditions: Bruxism
Interventions: DEVICE: Grindcare|DEVICE: Grindcare - inactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Occurrence, Diagnosis and Treatment of Neck and Back Pain in Helicopter Pilots.
Status: COMPLETED
Conditions: Low Back Pain|Neck Pain|Muscular Atrophy
Interventions: OTHER: Low back exercises 1|OTHER: Low back exercise 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MONITORING NEUROMUSCULAR BLOCK IN PAEDIATRIC ANAESTHESIA
Status: NOT_YET_RECRUITING
Conditions: Anesthesia,General|Neuromuscular Blockade|Tracheal Intubation
Interventions: DEVICE: TOF monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Increasing Measles Vaccination Coverage Through Supplementation With an SQ-LNS Incentive in Children Aged 6-23 Months
Status: RECRUITING
Conditions: Immunization Coverage|Vaccination|Nutrition
Interventions: DIETARY_SUPPLEMENT: Small-quantity lipid-based nutrition supplements (SQ-LNS) NutriVax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleep Timing, Eating and Activity Measurement Study
Status: RECRUITING
Conditions: Sleep|Circadian Rhythm Disorders|Dietary Habits
Interventions: BEHAVIORAL: Sleep Extension (Early)|BEHAVIORAL: Sleep Extension (Late)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcome of Physiotherapy After Surgery for Cervical Disc Disease: a Prospective Multi-Centre Trial
Status: COMPLETED
Conditions: Radiculopathy
Interventions: OTHER: Customary treatment|OTHER: Structured behavioural medicine program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxia and Upper Extremity EMG Recordings in Individuals With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Uveal Melanoma
Interventions: BIOLOGICAL: BPX-701|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic And Bioavailability Study of Intravenous Danoprevir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: danoprevir|DRUG: placebo|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Study for the Treatment of Significant Steatosis With Xenical Followed by Treatment of Hepatitis C With Pegasys/Copegus
Status: COMPLETED
Conditions: Fatty Liver|Hepatitis C
Interventions: DRUG: Xenical, Pegasys, Copegus|BEHAVIORAL: Xenicare Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus
Status: NOT_YET_RECRUITING
Conditions: Tinnitus, Subjective|Vagus Nerve Stimulation|Music Therapy|Double-Blind Method|Female|Male|Humans|Treatment Outcome
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation Paired with Tailor-Made Notched Music Therapy|DEVICE: Tailor-made Notched Music Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986205
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Root Coverage Procedures and Buccal Vestibular Depth
Status: COMPLETED
Conditions: Shallow Vestibular Depth|Gingival Recession
Interventions: PROCEDURE: Vertically coronally advanced flap combined with connective tissue graft.|PROCEDURE: Free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRD Guiding Treatment After Almonertinib Induction Therapy for EGFRm+ Stage III NSCLC in the MDT Diagnostic Model.
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia
Status: RECRUITING
Conditions: Scarring Alopecia|Androgenetic Alopecia
Interventions: DEVICE: Sciton HALO 1470nm Non-ablative laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Comparability of 2D and 4D Ultrasound Measurements
Status: WITHDRAWN
Conditions: Carpal Tunnel
Interventions: PROCEDURE: 4D Ultrasound|PROCEDURE: 2D ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pediatric Percutaneous Ultrasound Gastrostomy Technique
Status: RECRUITING
Conditions: Gastrostomy|Gastrostomy Complications|Pediatric Disorder|Ultrasound
Interventions: DEVICE: Percutaneous Ultrasound Gastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy|Men|Male Contraception
Interventions: DRUG: Nestorone + Testosterone Combination Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Acupressure on Pain, Menstrual Symptoms, and General Comfort in Adolescents With Primary Dysmenorrhea
Status: RECRUITING
Conditions: Pain|Dysmenorrhea Primary|Signs and Symptoms
Interventions: OTHER: Acupressure|OTHER: Placebo acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Acupressure on Preoperative Anxiety and Postoperative Pain and Nausea-Vomiting
Status: COMPLETED
Conditions: Anxiety State|Pain|Vomiting|Nausea
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise and Post-COVID/ Long-COVID: Effects of Different Training Modalities on Various Parameters in People Affected by the Sequelae of COVID-19
Status: COMPLETED
Conditions: Long COVID-19|Post-COVID-19 Syndrome|COVID-19
Interventions: OTHER: endurance training|OTHER: concurrent training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relationships in Good Hands - Clinical and Cost-effectiveness of Dyadic Developmental Psychotherapy
Status: RECRUITING
Conditions: Mental Health|Psychiatric Problems|Child Neglect|Maltreatment|Adoption|Child Behaviour Problem|DDP
Interventions: BEHAVIORAL: Dyadic Developmental Psychotherapy (DDP)|BEHAVIORAL: Services as Usual (SAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vicriviroc in HIV-Treatment Experienced Subjects (Study P04405AM5)
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Vicriviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Safety and Efficacy of Treatment With ORA102 Combined With Avastin (Bevacizumab) Versus Avastin Alone, in Patients With Neovascular Age Related Macular Degeneration (AMD)
Status: UNKNOWN
Conditions: Macular Degeneration
Interventions: DRUG: ORA102 and Avastin|DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficiency)
Status: UNKNOWN
Conditions: Thalassemia
Interventions: DRUG: Colla corii asini|DRUG: a Simulate Agent of Colla corii asini granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer
Status: RECRUITING
Conditions: Metastatic Tumors
Interventions: RADIATION: palliative radiotherapy|RADIATION: Stereotactic ablative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
Status: RECRUITING
Conditions: Heart Failure|Heart Dysfunction
Interventions: DRUG: Sacubitril-valsartan|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the 6-minute Walking Test in a Corridor and on a Non-motorized Treadmill
Status: COMPLETED
Conditions: Walking, Difficulty
Interventions: DIAGNOSTIC_TEST: 6-minutes walking test on a corridor|DIAGNOSTIC_TEST: 6-minutes walking test on a treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pediatric Switch Study for Children and Adolescent Patients With Epilepsy
Status: COMPLETED
Conditions: Pediatric Epilepsy
Interventions: DRUG: Depakote Delayed-Release/Depakote Sprinkle|DRUG: Depakote ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Pimecrolimus Cream, 1% and Elidel® Cream, 1% in Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus Cream, 1%|DRUG: Placebo Cream|DRUG: Pimecrolimus Cream, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Cough and Small Fiber Neuropathy
Status: RECRUITING
Conditions: Chronic Cough|Type 2 Diabetes
Interventions: OTHER: Cough assessment|OTHER: Neurological tests and cardiovascular tests|OTHER: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes
Status: ACTIVE_NOT_RECRUITING
Conditions: Hot Flashes|Sleep|Menopause|Cardiovascular Diseases|Epigenetics|DNA Methylation
Interventions: DIAGNOSTIC_TEST: Polysomnography|DIAGNOSTIC_TEST: Skin conductance|GENETIC: ALU and LINE-1 DNA methylation analysis|DIAGNOSTIC_TEST: The Menopause-Specific Quality of Life Questionnaire (MENQOL)|DIAGNOSTIC_TEST: Pittsburgh Sleep Quality Index (PSQI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Duloxetine Tibial Plateau
Status: WITHDRAWN
Conditions: Tibial Plateau Fracture|Pain, Postoperative
Interventions: DRUG: Duloxetine|OTHER: Placebo|OTHER: Standard of care (SOC) for tibial plateau surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Composite Variability Index Versus Bispectral Index (BIS)
Status: COMPLETED
Conditions: Sedation During
Interventions: DRUG: propofol + remifentanil 0 ng/ml|DRUG: propofol + remifentanil 2 ng/ml|DRUG: propofol + remifentanil 4 ng/ml|DRUG: propofol + remifentanil 6 ng/ml|DRUG: propofol + remifentanil 0 ng/ml|DRUG: propofol + remifentanil 2 ng/ml|DRUG: propofol + remifentanil 6 ng/ml|DRUG: propofol + remifentanil 6 ng/ml|DRUG: propofol + remifentanil 0 ng/ml|DRUG: propofol + remifentanil 2 ng/ml|DRUG: propofol + remifentanil 4 ng/ml|DRUG: propofol + remifentanil 6 ng/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol
Status: COMPLETED
Conditions: Recovery
Interventions: DRUG: REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]|DRUG: Flumazenil|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Kyphosis in the Mean Term in Patients Treated With Kyphoplasty Alone in the Management of Stable Traumatic Compression Fractures of the Thoracolumbar Spine
Status: UNKNOWN
Conditions: Thoracolumbar Spine
Interventions: OTHER: radiography standard
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Bilateral Retrolaminar Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Status: RECRUITING
Conditions: Retrolaminar Block|Analgesia|Adolescent|Idiopathic Scoliosis
Interventions: PROCEDURE: retrolaminar block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-3 Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: No aspirin|DRUG: 1-month DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy of a Mindfulness- and Acceptance-Based Smartphone App for PTSD: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness/Acceptance-Based Smartphone App (MABSA) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Robot-assisted Therapy With Mirror Priming in Stroke Patients
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: Robotic training with mirror therapy|BEHAVIORAL: Robotic-assisted training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nepafenac Once Daily for Macular Edema - Study 2
Status: COMPLETED
Conditions: Non-Proliferative Diabetic Retinopathy|Cataract
Interventions: DRUG: Nepafenac Ophthalmic Suspension, 0.3%|OTHER: Vehicle|DRUG: Prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Techniques of Combination Therapy for Treatment of Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Treatment for Obstructive Sleep Apnea
Interventions: DEVICE: Nuance Pro|DEVICE: autoPAP|DEVICE: TAP PAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery and Immunotherapy (Pembrolizumab) for the Treatment of Recurrent Meningioma
Status: RECRUITING
Conditions: Grade I Meningioma, Adult|Grade II Meningioma, Adult|Grade III Meningioma, Adult|Recurrent Meningioma
Interventions: DRUG: Pembrolizumab|PROCEDURE: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Pulse Width Used in Transcutaneous Electrical Nerve Stimulation for Treating Nocturnal Enuresis in Children
Status: RECRUITING
Conditions: Nocturnal Enuresis|Bedwetting
Interventions: DEVICE: Pulse Width 260us|DEVICE: Pulse Width 50us
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cortex Eucommiae (CE: Eucommia Ulmoides Oliver Extract) in Subjects With Mild Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: CE|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Neural Response Variability as a Single-patient Predictor of Successful CBT in Clinical Psychiatry
Status: RECRUITING
Conditions: Psychiatric Disorder|Depression|Anxiety Disorders|Insomnia
Interventions: BEHAVIORAL: Internet-delivered cognitive behavioral therapy for major depressive disorder|BEHAVIORAL: Internet-delivered cognitive behavioral therapy for insomnia|BEHAVIORAL: Internet-delivered cognitive behavioral therapy for social anxiety disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in Italy
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Relapse Leukemia|Refractory Leukemia
Interventions: DRUG: Venetoclax
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutrition and Exercise for Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Amino acids|DRUG: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non Surgical Therapy of Periodontitis in Diabetes Patients: the Adjunctive Use of Probiotics
Status: UNKNOWN
Conditions: Diabetes|Periodontitis
Interventions: OTHER: Probiotic|OTHER: Placebo|PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination GRA and SGLT-2i Treatment in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Dapagliflozin 10 MG [Farxiga]|DRUG: REMD-477|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Increasing Colorectal Cancer Screening in a Safety-net Health System With a Focus on the Uninsured: Benefits and Costs
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Mailed invitations for FIT test kits|OTHER: Mailed invitations for a colonoscopy|OTHER: Visit Based Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise and QUality Diet After Leukemia: The EQUAL Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Survivors of Childhood Leukemia
Interventions: BEHAVIORAL: individual diet & physical activity counselor and website through Healthways at Hopkins|BEHAVIORAL: self directed weight loss|BEHAVIORAL: questionnaires|OTHER: fasting blood draw, measurement of height, weight and waist circumference, and blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 Years
Status: TERMINATED
Conditions: Herpes Simplex
Interventions: BIOLOGICAL: Lower dose formulation of HSV vaccine (GSK4108771A)|BIOLOGICAL: Low dose formulation of HSV vaccine (GSK4108771A)|BIOLOGICAL: Medium dose formulation of HSV vaccine (GSK4108771A)|BIOLOGICAL: High dose formulation of HSV vaccine (GSK4108771A)|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glycerin Suppositories to Reduce Jaundice in Premature Infants
Status: COMPLETED
Conditions: Idiopathic Hyperbilirubinemia|Neonatal Hyperbilirubinemia|Prematurity
Interventions: PROCEDURE: Phototherapy|DRUG: glycerin suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
Status: NOT_YET_RECRUITING
Conditions: Myopia, Progressive
Interventions: DEVICE: frame lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 10 mg in Japanese Healthy Male Adult Subjects
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: DRUG: Rivaroxaban (BAY 59-7939, Xarelto) in ODT form|DRUG: Rivaroxaban (BAY 59-7939, Xarelto) in film-coated form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities
Status: RECRUITING
Conditions: Diabetic Neuropathy, Painful
Interventions: DRUG: Incobotulinumtoxin-A 100 UNIT Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 Status and Response to Vitamin B12 Supplementation in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin B12 Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer, Nonsmall Cell
Interventions: DRUG: Toripalimab+Chemotherapy|DRUG: Toripalimab+Chemotherapy followed by consolidation toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Live Attenuated Chikungunya Vaccine in a Previously Epidemic Area
Status: COMPLETED
Conditions: Chikungunya
Interventions: BIOLOGICAL: MV-CHIK|BIOLOGICAL: MMR-vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: WELL-being Improvement Following a SOphrology Intervention in Hospital Staff
Status: RECRUITING
Conditions: Stress Related Disorder|Sophrology|Neurolinguistic Programming
Interventions: BEHAVIORAL: sophrology / neurolinguistic programming intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study With a Robotic Assistant in Patients Requiring a Spinal Transpedicular Fixation
Status: COMPLETED
Conditions: SPINAL Fracture|Vertebral Fractures|Spinal Stenosis|Kyphosis|Lumbar Spinal Stenosis|Thoracolumbar Kyphosis
Interventions: PROCEDURE: Robot assisted spinal transpedicular fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Benchmarking Intra-tumor Heterogeneity In Ovarian Cancer: Linking In-vivo Imaging Phenotypes With Histology And Genomics
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: PROCEDURE: PET/CT Scan|PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk-guided Disease Management Plan to Prevent Heart Failure in Patients Treated With Previous Chemotherapy (REDEEM)
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Heart Failure intervention (Cardio-Oncology Disease Management Plan (CO-DMP)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Safety Study of the Progesterone Vaginal Ring in Women Undergoing Assisted Reproductive Technology Procedures
Status: COMPLETED
Conditions: Progesterone Supplementation in Women Undergoing ART
Interventions: DRUG: Progesterone vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing a New Protocol for Early Mucositis and Peri-implantitis Treatment Using an Air-polishing Device
Status: WITHDRAWN
Conditions: Peri-Implantitis|Mucositis
Interventions: DEVICE: Air-polishing device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing Intervals of Opioid Medication for Chronic Pain
Status: WITHDRAWN
Conditions: Chronic Pain
Interventions: DRUG: Extended Release Opioid Formulation, Shortened Intervals|DRUG: Extended Release Opioid Formulation, Standard intervals|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Profile of Levodopa Administered With Continuous Administration of ND0611
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: ND0611|DRUG: ND0611
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TTP and aHUS in Complicated Pregnancies
Status: UNKNOWN
Conditions: Thrombotic Thrombocytopenic Purpura|Atypical Hemolytic Uremic Syndrome|Pre-Eclampsia|HELLP Syndrome|Thrombocytopenia|IUGR|Stillbirth|Thrombotic Microangiopathies
Interventions: DIAGNOSTIC_TEST: ADAMTS 13, complement and angiogenic biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hematogenous Osteomyelitis (AHO) (MK-3009-006)
Status: COMPLETED
Conditions: Acute Hematogenous Osteomyelitis
Interventions: DRUG: Daptomycin|DRUG: Vancomycin (or equivalent)|DRUG: Nafcillin (or equivalent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Efficacy and Safety of SJP002 Ophthalmic Solution in Patients With Dry Eye Syndrome.
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: SJP002 BID|DRUG: SJP002 QID|DRUG: SJP002 Placebo 1|DRUG: SJP002 Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Januvia (Sitagliptin) on Oxidative Stress in Obese Type 2 Diabetic Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Januvia (Sitagliptin) 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of LDP Combined With CDP1 in Patients With Advanced Malignant Tumor
Status: UNKNOWN
Conditions: Advanced Malignant Tumor
Interventions: DRUG: Human Anti-PD-L1 Monoclonal Antibody Injection (LDP) Combined with Recombinant Anti-EGFR Human Mouse Chimeric Monoclonal Antibody Injection (CDP1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M07D1 in Patients With HER2-mutated, Locally Advanced or Metastatic Non-small-cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: BL-M07D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-1 Combined Cisplatin HIPEC for Palliative Operation Gastric Cancer of Stage IV Limited Peritoneal Metastasis
Status: UNKNOWN
Conditions: Stage IV Gastric Cancer
Interventions: DRUG: S-1 plus cisplatin HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry Platform Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Diffuse Large B-cell Lymphoma (DLBCL)|Follicular Lymphoma (FL)|Mantle Cell Lymphoma (MCL)|Marginal Zone Lymphoma (MZL)|Waldenström's Macroglobulinemia (WM)
Interventions: OTHER: Routine care as per site standard.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Clinical Performance of a Biological Matrix Used in Abdominal Wall Reconstruction
Status: RECRUITING
Conditions: Abdominal Wall Defect|Abdominal Wall Injury|Abdominal Hernia
Interventions: DEVICE: CELLIS (Porcine Acellular Dermal Matrix, PADM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enriched Heparin Anti COVID-19 Trial
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Heparin sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Adacel Polio Vaccine
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis
Interventions: BIOLOGICAL: TdcP-IPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Quality Protein for Assisting With Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Egg breakfast (EB)|BEHAVIORAL: Weight Loss Counseling|BEHAVIORAL: Weight Loss Diet|BEHAVIORAL: Cereal Breakfast (CB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI
Status: UNKNOWN
Conditions: Heart Attack|Enlarged Heart
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-FLT3 CAR-T Cell (TAA05 Cell Injection) in the Treatment of Relapsed / Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Fludarabine + Cyclophosphamide + TAA05 Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Depigmented Extract of Phleum in Local Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: DEPIGOID phleum|BIOLOGICAL: DEPIGOID Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ORal IrON Supplementation With Ferric Maltol in Treating Iron Deficiency and Anaemia in Patients With Heart Failure (ORION-HF)
Status: RECRUITING
Conditions: Heart Failure, Left-sided|Anemia, Iron Deficiency
Interventions: DRUG: Ferric maltol 30 mg (Feraccru®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT