pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)
Status: COMPLETED
Conditions: Circulatory Failure|Cardiac Arrest
Interventions: DEVICE: rapid pulse confirmation device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Venous Thromboembolic Event (VTE) Prophylaxis in Medically Ill Patients
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Enoxaparin|DRUG: Rivaroxaban placebo|DRUG: Enoxaparin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Insulin Requirement for Pure-protein Meal in Children With Type 1 Diabetes on Insulin Pumps.
Status: UNKNOWN
Conditions: Diabetes type1
Interventions: DRUG: Insulin glulisine|DRUG: Insulin aspart|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous (IV) Citalopram on Emotional Brain Activity in Healthy Young and Elderly Adults
Status: TERMINATED
Conditions: Healthy Young and Elderly Volunteers
Interventions: DRUG: Intravenous Citalopram|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: ASP7317|DRUG: tacrolimus|DRUG: trimethoprim-sulfamethoxazole|DRUG: Acyclovir|DRUG: Nystatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Pharmacokinetic Disposition and Urinary Excretion of Albendazole
Status: COMPLETED
Conditions: Soil Transmitted Helminthiasis|Neglected Tropical Diseases
Interventions: DRUG: Albendazole.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Catheter Type on Efficacy of Percutaneous Caudal Adhesolysis
Status: NOT_YET_RECRUITING
Conditions: Failed Back Surgery Syndrome
Interventions: PROCEDURE: caudal adhesolysis using RACZ Catheter|PROCEDURE: caudal adhesiolysis using NAVI Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation
Status: UNKNOWN
Conditions: Slow Transit Constipation
Interventions: DRUG: Fecal microbiota transplantation (FMT)|BEHAVIORAL: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Multi Centre Trial on Bipolar Radiofrequency Ablation of Atrial Fibrillation
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Bipolar radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Korean Study Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: bimekizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Direct Superior Approach for Total Hip Arthroplasty as an Effective Alternative to Traditional Posterior Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Direct Superior Approach|DEVICE: Total Hip Arthroplasty|PROCEDURE: Posterior Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Study of Pulse Wave Velocity and Augmentation Index in Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: SphygmoCor version 7, AtCor Medical, Sydney, Australia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Intravenous Lidocaine After Colorectal Surgery: LIDOREHAB
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BRIDGE Device for Post-operative Pain Control
Status: TERMINATED
Conditions: Liver Failure|Liver Diseases, Alcoholic|Liver Diseases|Pain, Postoperative|Transplant; Failure, Liver|Liver Cirrhosis, Biliary
Interventions: DEVICE: BRIDGE device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.
Status: COMPLETED
Conditions: Heart Failure (HF)|Ventricular Dysfunction, Left
Interventions: DRUG: AdreView (Iobenguane I 123 Injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With DMARDs Versus DMARDs Alone in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Combination With DMARDs
Interventions: DRUG: DMARDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide Tablet|DRUG: Lacosamide Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation in MS Using Translingual Stimulation
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: COMBINATION_PRODUCT: PT plus translingual stimulation device|COMBINATION_PRODUCT: PT plus translingual stimulation control device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Volume Replacement (PVR) Therapy With Colloid and Crystalloid Solutions
Status: COMPLETED
Conditions: Plasma Volume Replacement|Surgery of the Pancreatic Head
Interventions: DRUG: HES 10%|DRUG: HES 6%|DRUG: balanced electrolyte solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eicosapentaenoic Acid Cerebral Vasospasm Therapy Study
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DRUG: Eicosapentaenoic acid ethyl ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Benefit of an Individualised Treatment Plan (VitalCare) VS SOC in OSA Patients Treated With CPAP/APAP
Status: UNKNOWN
Conditions: Obstructive Sleep Apnoea Syndrome (OSAS)
Interventions: OTHER: individualised treatment plan (VitalCare) and associated remote medical monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Peripheral Nerve Injury
Status: UNKNOWN
Conditions: Peripheral Nerve Injury
Interventions: DRUG: Neovasculgen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bare Metal Stent Versus Drug Coated Balloon With Provisional Stenting in Non-ST-Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Coronary Heart Disease|NSTEMI
Interventions: DEVICE: Stent|COMBINATION_PRODUCT: SeQuent(R) Please coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury|Postoperative Pain
Interventions: PROCEDURE: Popliteal plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GC012F Injection in Subjects With Refractory Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: GC012F Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Japanese Participants With Chronic Hepatitis C (MK-5172-058)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Elbasvir|DRUG: Placebo to Grazoprevir|DRUG: Placebo to Elbasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Etoposide|BIOLOGICAL: Loncastuximab Tesirine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetics and Pharmacodynamics of Peginterferon BIP48 and 40kDa in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Viral Hepatitis C
Interventions: DRUG: BIP 48|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus Stent in Patients With Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Atherosclerosis
Interventions: DEVICE: coronary stent|DEVICE: stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Physical Home-rehabilitation by Information and Communications Technology. Games for Older Adults Active Life (GOAL)
Status: COMPLETED
Conditions: Cognitive Dysfunction|Mild Cognitive Impairment|Vascular Cognitive Impairment
Interventions: OTHER: Tele-rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery
Status: COMPLETED
Conditions: Esophageal Neoplasms|Stomach Neoplasms|Weight Loss|Malnutrition|Pancreatic Neoplasms|Duodenal Neoplasms
Interventions: DRUG: Octreotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BI 811283 in Combination With Cytarabine in Previously Untreated AML Ineligible for Intensive Treatment
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: BI 811283 (d 1 and 15)|DRUG: Cytarabine|DRUG: BI 811283 (d1)|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively Treated
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: EFV/FTC/TDF + Losartan|DRUG: EFV/FTC/TDF|DRUG: FTC/TDF + MK-0518|DRUG: FTC/TDF+MK-0518+Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G6PD Assessment Before Primaquine for Radical Treatment of Vivax Malaria
Status: COMPLETED
Conditions: Vivax Malaria
Interventions: DRUG: Chloroquine|DRUG: Primaquine 0.25 mg/kg/day|DRUG: Primaquine 0.75 mg/kg weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Follow-up Study of the Effectiveness of Virtual Reality Therapy in Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Neurorehabilitation|OTHER: Neurorehabilitation|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Oxaliplatin-induced Neuropathic Pain by a Specific Diet
Status: COMPLETED
Conditions: Neuropathy|Digestive Cancer System
Interventions: BEHAVIORAL: Polyamines depleted diet, associating Polydol® cans and predefined menus low in polyamines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community
Status: COMPLETED
Conditions: Aging|Cognitive Change
Interventions: BEHAVIORAL: Adaptive Cognitive Control Trainer (ACCT)|BEHAVIORAL: Active Control App
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Dual Anti-Platelet Therapy (DUAL-ACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Coronary Artery Disease
Interventions: OTHER: 3 months dual anti-platelet therapy|OTHER: 12 months dual anti-platelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Larynx|Squamous Cell Carcinoma of the Hypopharynx
Interventions: DRUG: CRGD-ZW800-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Propofol Effects on Mitral Valve Annular Velocity
Status: COMPLETED
Conditions: Valvular Heart Disease|Coronary Artery Disease
Interventions: DRUG: Propofol 1.0mcg|DRUG: Propofol 2.0mcg|DRUG: Propofol 3.0mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Pharmacodynamics of OP0201 Compared to Placebo in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adults
Interventions: COMBINATION_PRODUCT: Drug:OP0201|COMBINATION_PRODUCT: Drug: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Optimization of Selenoprotein P in Chinese Subjects
Status: COMPLETED
Conditions: Selenium Deficiency
Interventions: DIETARY_SUPPLEMENT: 20 µg selenium|DIETARY_SUPPLEMENT: 40 µg selenium|DIETARY_SUPPLEMENT: 60 µg selenium|DIETARY_SUPPLEMENT: 80 µg selenium|DIETARY_SUPPLEMENT: 100 µg selenium|DIETARY_SUPPLEMENT: 120 µg selenium|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Status: RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: NXT007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bursa Augmentation in Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Interventions: PROCEDURE: Doppler ultrasonography after bursa augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blood Isoflurane Concentration and the Oxygenator
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DEVICE: Sorin Inspire Oxygenator|DEVICE: Medtronic Affinity Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole
Status: COMPLETED
Conditions: Invasive Fungal Infections
Interventions: DRUG: SUBA itraconazole|DRUG: Conventional itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)
Status: WITHDRAWN
Conditions: Wet Age-related Macular Degeneration|Age-related Macular Degeneration|AMD|Wet AMD|Macular Degeneration
Interventions: DEVICE: IRay|DEVICE: IRay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy of Bifidobacterium BB-12® in the Treatment of Infantile Colic
Status: COMPLETED
Conditions: Infantile Colic|Colic, Infantile
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium, BB-12® (Bifidolactis Infant)|DIETARY_SUPPLEMENT: Bifidolactis Infant Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms
Interventions: DRUG: Bupivacain|DRUG: bupivacain+dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing the Safety and Effectiveness of Intracoronary Stem Cells in Patients With Refractory Angina
Status: RECRUITING
Conditions: Refractory Angina Pectoris|Refractory Angina
Interventions: BIOLOGICAL: Bone marrow aspiration and a single intracoronary infusion of autologous bone marrow-derived mononuclear cells.|PROCEDURE: Sham bone marrow aspiration and sham cell infusion (insertion of vascular access sheath).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)
Status: COMPLETED
Conditions: Syphilis
Interventions: DIAGNOSTIC_TEST: Access to Facility based Syphilis Testing|DIAGNOSTIC_TEST: Syphilis Self-Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of a High or Low Salycilate Diet on Urinary LTE4 and Clinical Features in AERD
Status: UNKNOWN
Conditions: Aspirin-exacerbated Respiratory Disease|Aspirin-Sensitive Asthma With Nasal Polyps|Samter's Syndrome|Widal Syndrome
Interventions: OTHER: Low salycilate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Tatelo Plus Study
Status: NOT_YET_RECRUITING
Conditions: HIV|HIV Infections
Interventions: DRUG: PGDM1400LS|DRUG: VRC07-523LS|DRUG: PGT121.414.LS|DRUG: ART Regimen prior to enrolling in Step 1a|DRUG: ART Regimen prior to enrolling in Step 1b|OTHER: Analytic Treatment Interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Ductal Carcinoma in Situ or Pure Micro-invasive Extended Breast
Status: COMPLETED
Conditions: Intraductal Carcinoma and Lobular Carcinoma in Situ
Interventions: PROCEDURE: sentinel node biopsy and mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Letrozole and RAD001 With Advanced or Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: Letrozole|DRUG: RAD001 (Everolimus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Cadonilimab With SOX as Neoadjuvant Therapy for Resectable Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma.
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: S-1, Oxaliplatin, Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Basal Plus One Insulin Regimen With a Biphasic Insulin Regimen in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE (HOE901)|DRUG: Insulin aspart|DRUG: Insulin Glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness & Compassion Meditation-based Exposure Therapy|BEHAVIORAL: Present Centered Therapy for PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Akt Inhibitor MK2206|DRUG: Bendamustine Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Booster Dose of sIPV Co-administered With MMR and HepA-I.
Status: NOT_YET_RECRUITING
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: sIPV|BIOLOGICAL: MMR|BIOLOGICAL: HepA-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aztreonam Lysine for Pseudomonas Infection Eradication Study
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Aztreonam for Inhalation Solution (AZLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Picoprep With Mannitol and Bisacodyl for Colon Cleansing in Preparation for Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: sodium picosulfate, magnesium oxide and citric acid (Picoprep®)|DRUG: mannitol|DRUG: Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Trauma Informed Adaptation of Mindfulness-Based Relapse Prevention for Women in Substance Use Treatment
Status: COMPLETED
Conditions: Substance Use Disorders|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma Informed Mindfulness-Based Relapse Prevention|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Banded One Anastomosis Gastric Bypass With Use Shape-memory Ring Versus Non-banded One Anastomosis Gastric Bypass
Status: WITHDRAWN
Conditions: Obesity
Interventions: PROCEDURE: Laparoscopic one anastomosis gastric bypass|DEVICE: A shape-memory ring for adjustable gastric banding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability and Pharmacokinetics of Multiple Ascending Doses of VCH 916 in Subjects With Chronic Hep C Infection
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: VCH 916|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Depot Formulation of Aripiprazole as Maintenance Treatment in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ginko and Cistanche Against Fatigue Symptoms
Status: COMPLETED
Conditions: Mental Fatigue|Fatigue|Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: Experimental: Nutrilite® Low dose|DIETARY_SUPPLEMENT: Experimental: Nutrilite® High dose|DIETARY_SUPPLEMENT: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Preoperative Nursing Visit on Anxiety and Pain Level of Patients After Surgery
Status: COMPLETED
Conditions: Nurse-Patient Relations
Interventions: PROCEDURE: Control-Service Nurse Group|PROCEDURE: Nursing Visiting Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Monounsaturated Fatty Acids on Intestinal Lipid Metabolism in Insulin Resistant Subjects (MUFA )
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Interventions: OTHER: Monounsaturated fatty acids diet|OTHER: Saturated fatty acids diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Smoking Habits and Smoking Cessation in Young Adults
Status: COMPLETED
Conditions: Smoking Cessation|Smoking|Habits
Interventions: DRUG: varenicline|DRUG: Nicotine cutaneous patch 15mg/16h|DRUG: Nicotine cutaneous patch 10mg/16h|OTHER: Placebo cutaneous patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Sleep Apnea Syndromes
Interventions: DEVICE: Autotitrating Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IRESSA in Combination With Cisplatin & Radiotherapy in Patients With Advanced Head & Neck Carcinoma
Status: COMPLETED
Conditions: Cancer of Head and Neck
Interventions: DRUG: Gefitinib, Cisplatin and Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of KB003 In Biologics-Inadequate Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: KB003|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Renin-Aldosterone Axis in Postural Tachycardia Syndrome
Status: COMPLETED
Conditions: Postural Orthostatic Tachycardia Syndrome (POTS)
Interventions: DRUG: Angiotensin II
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|GENETIC: TdT-mediated dUTP nick end labeling assay|OTHER: 3'-deoxy-3'-[18F]fluorothymidine|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|RADIATION: fludeoxyglucose F 18|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Daratumumab in Combination With Bortezomib, Thalidomide, and Dexamethasone Regimens in Newly Diagnosed Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Daratumumab in Combination with Bortezomib, Thalidomide, and Dexamethasone Regimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Non-small Cell Lung Cancer|Brain Metastasis
Interventions: DRUG: Pembrolizumab plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study (STOP AF PAS)
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation (PAF)
Interventions: DEVICE: Medtronic Arctic Front® Cardiac CryoAblation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen
Status: TERMINATED
Conditions: Overactive Bladder|Constipation|Lower Urinary Tract Symptoms
Interventions: DRUG: Baclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural Killer Cell Immunotherapy in Combination With PARP-inhibition in Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: NK cells|DRUG: Talazoparib 1 MG [Talzenna]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of iSONEP (Sonepcizumab/LT1009) to Treat Neovascular Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Neovascular Age Related Macular Degeneration
Interventions: BIOLOGICAL: iSONEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Profiling the Skin Microbiome in Response to Altreno in Acne Patients
Status: COMPLETED
Conditions: Acne|Healthy
Interventions: DRUG: Altreno|DRUG: Benzoyl peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Vitex Agnus-castus BNO 1095 (20 mg) in Women With Primary Dysmenorrhea
Status: RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: DRUG: Vitex agnus-castus BNO 1095 (20 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Platelet-rich Plasma and Topical 5% Minoxidil Combination in Male Androgenetic Alopecia
Status: ACTIVE_NOT_RECRUITING
Conditions: Androgenetic Alopecia
Interventions: COMBINATION_PRODUCT: Platelet-Rich Plasma and Topical 5% Minoxidil|DRUG: Topical 5% Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Trial of Extended Release Combination Tablet Codeine and Guaifenesin
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: IR Tablet under Fasted conditions|DRUG: ER Tablet under Fed Conditions|DRUG: ER Tablet under Fasted Conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Interim PET Scan to Modify Therapy in Advanced Hodgkin's Lymphoma in Order to Improve Outcomes
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Escalated BEACOPP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of Plerixafor in Healthy Subjects of Japanese Descent
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: plerixafor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Closone and Clopidogrel With Aspirin
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Closone|DRUG: Plavix with Astrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Far Infrared Therapy on Peripheral Artery Disease in Hemodialysis Patients
Status: UNKNOWN
Conditions: Peripheral Artery Disease
Interventions: DEVICE: WSTM TY101 FIR emitter (Far infrared therapy)|DEVICE: Placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage
Status: RECRUITING
Conditions: Intraventricular Hemorrhage
Interventions: DEVICE: IRRAflow|PROCEDURE: Standard ventriculostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: AGS-003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copanlisib in Combination With Venetoclax in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma.
Status: TERMINATED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Copanlisib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction
Status: RECRUITING
Conditions: Small Bowel Obstruction|Small Bowel Adhesion|Strangulation of Ileum
Interventions: PROCEDURE: Adhesiolysis|RADIATION: X-ray diagnostics|RADIATION: Computer tomography|PROCEDURE: Ultrasound|OTHER: General and biochemical blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate a Melanoma Helper Peptide Vaccine Plus Dabrafenib and Trametinib
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: BRAF inhibitor|BIOLOGICAL: 6MHP|DRUG: MEK inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept in Treating Patients With Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Secondary Myelodysplastic Syndromes
Interventions: BIOLOGICAL: ziv-aflibercept|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An 8-week Follow-up to Evaluate the Renewal of Corneal Nerves Structure and Function in Patients With Neurotrophic Keratopathy Treated With Recombinant Human Nerve Growth Factor (rhNGF) Eyedrops
Status: COMPLETED
Conditions: Neurotrophic Keratopathy
Interventions: DRUG: Cenegermin, recombinant human Nerve Growth Factor (rhNGF) eyedrops
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Enteral Olive Oil Supplement On Weight Gain and Development of Some Complications in Preterm
Status: COMPLETED
Conditions: Olive Oil Adverse Reaction|Nursing Caries|Enteral and Supplement Feeds Adverse Reaction|Preterm
Interventions: DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Nitric Oxide for Inhalation|DRUG: Nitric Oxide for Inhalation|DRUG: Nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Olanzapine vs. Aripiprazole in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: ShOckwave ballooN or Atherectomy With Rotablation in Calcified Coronary Artery Lesions, the SONAR Trial
Status: RECRUITING
Conditions: Calcified Atheroma|Coronary Artery Disease
Interventions: DEVICE: Rotablation of shockwave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/IIa Study of BR1733 in Subjects With Advanced Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Follicular Lymphoma|Peripheral T Cell Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: BR1733
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Endpoint Study of Ivermectin 0.5% Lotion
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Generic Ivermectin Lotion 0.5%|DRUG: Sklice® (Ivermectin) Lotion 0.5%|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theory-based Social Media Intervention for Non-medical Use of Prescription Opioids in Young Adults
Status: RECRUITING
Conditions: Young Adults|Past-3-month Non-medical Use of Prescription Opioids|Without Substance Use Disorders|Social Media Users
Interventions: BEHAVIORAL: Theory-based and peer-led intervention on Instagram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy of UP165 on Sleep Quality and Mood State in Healthy Adults
Status: COMPLETED
Conditions: Sleep Disturbance
Interventions: OTHER: UPI65 (Low Dose)|OTHER: UP165 (High Dose)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With Carotid Atherosclerotic Plaques
Status: WITHDRAWN
Conditions: Carotid Atherosclerosis
Interventions: COMBINATION_PRODUCT: Sonodynamic therapy (SDT)|COMBINATION_PRODUCT: pseudo-SDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Open Angle|Ocular Hypertension
Interventions: DRUG: Xalacom|DRUG: Cosopt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Anticoagulants for Extended VEnous Thromboembolism
Status: TERMINATED
Conditions: Venous Thromboembolism
Interventions: DRUG: Warfarin|DRUG: Apixaban 2.5 MG|DRUG: Rivaroxaban 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Versus EUS FNAC in Pancreatic Masses
Status: UNKNOWN
Conditions: Pancreatic Neoplasm|Pancreatic Cyst|Pancreatic Abscess
Interventions: PROCEDURE: US|PROCEDURE: EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of HY004 Cell Injection in the Treatment of Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Non-hodgkin Lymphoma
Interventions: BIOLOGICAL: HY004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web Based Progressive Muscle Relaxation Exercise on Clinical Stress and Anxiety of Nursing Students
Status: COMPLETED
Conditions: Anxiety|Stress|Nursing Students|Relaxation Program
Interventions: OTHER: progressive relaxation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Heart Failure|Inotropic Agents|Safety Issues|Effect of Drug|Cardiac Event|Transcatheter Aortic Valve Replacement
Interventions: DRUG: Levosimendan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Educational Nutrition and Exercise on the Regulation of Appetite Through Exosomes in Type 2 Diabetics
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Nutritional education program|OTHER: The High-Intensity Interval Training (HIIT)|OTHER: The Moderate-Intensity Continuous Training (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Fabricated foods with lupin protein|DIETARY_SUPPLEMENT: Mannitol|DIETARY_SUPPLEMENT: Arginine|DIETARY_SUPPLEMENT: Fabricated foods with milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting Response to Intra-Articular Corticosteroid Injection in Patients With Osteoarthritis of the Glenohumeral Joint
Status: TERMINATED
Conditions: Osteoarthritis of the Glenohumeral Joint
Interventions: PROCEDURE: intraarticular corticosteroid injections (IACSI)|DRUG: corticosteroid injections|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIBW2992 (Afatinib) in Advanced (EGFR-FISH +) NSCLC (Non Small Cell Lung Cancer) Patients
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BiBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications
Status: COMPLETED
Conditions: Heterotopic Ossification|Hip Arthropathy|Myositis Ossificans Traumatica, Thigh
Interventions: RADIATION: Radiation|DRUG: Diclofenac
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p