pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of SPEAC® System Data on Therapeutic Decisions Related to Convulsive Seizure Patients With a Recent Non-diagnostic EMU Visit
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: SPEAC System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IB Non-Small Cell Lung Carcinoma AJCC v7|Stage II Non-Small Cell Lung Cancer AJCC v7|Stage IIA Non-Small Cell Lung Carcinoma AJCC v7|Stage IIB Non-Small Cell Lung Carcinoma AJCC v7|Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Endodontic Retreatment in One or Two Visits
Status: RECRUITING
Conditions: Endodontic Disease|Endodontically Treated Teeth|Root Canal Infection
Interventions: PROCEDURE: Non-surgical root canal retreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of 20, 40, and 80mg of Sildenafil Three Times a Day in the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: sildenafil|DRUG: sildenafil|DRUG: placebo|DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Access to Chiropractic Care in Community Health Centers
Status: ENROLLING_BY_INVITATION
Conditions: Lower Back Pain
Interventions: OTHER: Institutional interventions|OTHER: PCPs interventions|OTHER: Patient interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)
Status: COMPLETED
Conditions: Primary Immune Deficiency
Interventions: BIOLOGICAL: Immune Globulin Subcutaneous (Human) (SCIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Localized Concurrent Chemo-radiation Therapy and Sorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: CCRT|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
Status: COMPLETED
Conditions: Motor Function of Healthy Physiology
Interventions: DEVICE: TMS|DEVICE: tDCS|DEVICE: tACS|DEVICE: CPNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Dementia|Caregiver Burden|Assistive Technology
Interventions: DEVICE: The MapHabit System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Aplastic Anemia|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome|Previously Treated Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Cyclosporine|BIOLOGICAL: Filgrastim|DRUG: Methylprednisolone|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of GSK2798745 on Alveolar Barrier Disruption in a Segmental Lipopolysaccharide (LPS) Challenge Model
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: GSK2798745|DRUG: Placebo|DRUG: Lipoplysaccharide from Escherichia Coli|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Exposure and Effect in Standardized Research E-cigarette (SREC) Users
Status: RECRUITING
Conditions: Smoking, Cigarette
Interventions: DRUG: Standardized Research E-cigarette (SREC)|DRUG: Nicotine Mini-Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhanced Satiety With Pork Products Containing Dietary Fibre
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Animal protein|OTHER: Vegetable protein|OTHER: Dietary fiber (cereal food matrice)|OTHER: Dietary fiber (meat food matrice)|OTHER: Dietary fiber (vegetable food matrice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 18F-AlF-FAPi-04 PET/CT Imaging in Patients With Solid Tumor
Status: RECRUITING
Conditions: Tumor, Solid
Interventions: DRUG: Radiation: 18F-AlF-FAPi-04|DRUG: Radiation: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Evaluate Efficacy of Heart-protecting Musk Pill
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Heart-protecting Musk Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI)
Status: COMPLETED
Conditions: Alcoholism|Alcohol Abuse
Interventions: DRUG: Citalopram + MI|BEHAVIORAL: Placebo + MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigator Initiated Trial to Evaluate Efficacy and Safety of LAENNEC (Human Placenta Hydrolysate) Administered by Ultrasonography Guided Subacromial Bursa Injection in Patients With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: BIOLOGICAL: LAENNEC|OTHER: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|PROCEDURE: Computed Tomography|RADIATION: External Beam Radiation Therapy|PROCEDURE: Leukapheresis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Nelfilcon A contact lens|DEVICE: Narafilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Compliance During PegIntron and Rebetol Combination Therapy in Chronic Hepatitis C (Study P04690)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (Peginterferon alfa-2b)|DRUG: Rebetol (Ribavirin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lorlatinib After Failure of First-line Second-generation ALK Kinase Inhibitor in Patients With Advanced ALK-positive Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Investigating Safety and Performance of a New Urinary Intermittent Catheters in Healthy Volunteers
Status: COMPLETED
Conditions: Incontinence, Urinary
Interventions: DEVICE: Coloplast Test Catheter|DEVICE: Speedicath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protocols of IVF/ICSI in Poor Responders
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Minimal stimulation protocol|DRUG: Microflare protocol|PROCEDURE: IVF/ICSI cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LTX-315 and Adoptive T-cell Therapy in Advanced Soft Tissue Sarcoma (ATLAS-IT-04)
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: COMBINATION_PRODUCT: LTX-315 and TILs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High-intensity Laser Therapy on the Supraspinatus Tendon Using Shear Wave Elastography
Status: RECRUITING
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Physiotherapy program|OTHER: High intensity laser|OTHER: Sham high intensity laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Long-term Safety (12 Months) of the Combination of Aliskiren 300 mg and Hydrochlorothiazide 25 mg
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preserving Geriatric Muscle With an Osteoporosis Medication
Status: RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: Denosumab 60 MG/ML|DRUG: Zoledronic Acid 5Mg/Bag 100Ml Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Function in Elderly Patients With Mild to Moderate COVID-19 on Hemodialysis
Status: UNKNOWN
Conditions: COVID-19|Hemodiafiltration
Interventions: DIETARY_SUPPLEMENT: Oral nutritional supplement|BEHAVIORAL: Nutrition consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Surveillance on Lutathera® in Patients With Somatostatin Receptor Positive Gastroenteropancreatic Neuroendocrine Tumor in Korea
Status: COMPLETED
Conditions: Somatostatin Receptor-positive GEP-NET
Interventions: OTHER: Lutathera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Provide Complementary Efficacy, Safety and Patient Reported Outcomes Data in Participants With Active Relapsing Forms of Multiple Sclerosis (MS) in a Pragmatic Setting
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab 300 mg|DRUG: Ocrelizumab 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survey Study on Barrett's Esophagus Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroesophageal Reflux Disease|Barrett's Esophagus|Esophagus Adenocarcinoma
Interventions: BEHAVIORAL: Primary Care Provider Survey|BEHAVIORAL: Gastroenterologist Survey|BEHAVIORAL: Patient Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Isotretinoin Versus Excimer Light an Adjuvant in Treating Onychomycosis
Status: NOT_YET_RECRUITING
Conditions: Onychomycosis
Interventions: DRUG: ISOtretinoin 10 MG|DEVICE: excimer light|DRUG: Itraconazole 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: STUDY The Effect of HNF-4A G60D Variant on the In VIVO CYP2D6 Activity By Tolterodine Pharmacokinetic Study
Status: COMPLETED
Conditions: Genotype Guided(HNF4a)|Healthy Subjects
Interventions: DRUG: Tolterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dietary Protein Quality for Skeletal Muscle Anabolism in Older Adults
Status: COMPLETED
Conditions: Sarcopenia|Dietary Protein|Resistance Exercise
Interventions: OTHER: Resistance Exercise|DIETARY_SUPPLEMENT: Protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection
Status: COMPLETED
Conditions: Coronary Heart Disease|Obesity|Weight Loss
Interventions: OTHER: Alternate day fasting|OTHER: Calorie restriction|OTHER: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Autologous Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing CD4+/CD8+ Central Memory T-lymphocytes JCAR014|DRUG: Cyclophosphamide|BIOLOGICAL: Durvalumab|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of Oral CPSI-2364 (Semapimod)
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: CPSI-2364 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Atorvastatin|DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intranasal Challenge of Healthy Adults With Respiratory Syncytial Virus (RSV)
Status: TERMINATED
Conditions: RSV Infection
Interventions: DRUG: Placebo|DRUG: MEDI-557
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of PAS on the Pharmacokinetics of Tenofovir in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Tenofovir disoproxil fumarate 300mg|DRUG: Para-aminosalicylic acid Ca granule 5.28 g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Acute Efficacy of Exercises Applied With Xbox and Biodex Devices in Pes Planus"
Status: NOT_YET_RECRUITING
Conditions: Pes Planus
Interventions: OTHER: Virtual|OTHER: biodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Salivary Procalcitonin (PCT) Levels and Serum PCT Levels
Status: RECRUITING
Conditions: Bacterial Infections|Children, Only|Procalcitonin|Saliva
Interventions: DIAGNOSTIC_TEST: Sliva Procalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of MedLogic LiquiBand Laparoscopic Versus Dermabond in the Closure of Surgical Incisions
Status: COMPLETED
Conditions: Laparoscopic Surgery
Interventions: DEVICE: LiquiBand Laparoscopic|DEVICE: Dermabond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients
Status: ENROLLING_BY_INVITATION
Conditions: Sepsis|Electronic Health Records|Clinical Decision Support Systems
Interventions: OTHER: Nurse SIRS alert|OTHER: Prescribing clinician SIRS alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-In-Human Study of Apramycin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Apramycin injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post Market Study Using The Elite IQ Device
Status: COMPLETED
Conditions: Hair Removal|Pseudo Folliculitis Barbae|Benign Vascular Lesion|Pigmented Lesions
Interventions: DEVICE: RF Non-Invasive Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Light Emitting Diode (LED) Mattress for Phototherapy of Jaundiced Newborns
Status: COMPLETED
Conditions: Hyperbilirubinemia, Neonatal
Interventions: DEVICE: Neolight Phototherapy Mattress|DEVICE: Standard-of-Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Status: COMPLETED
Conditions: Drug Use|Alcohol Use|Congestive Heart Failure|Pneumonia|Acute Myocardial Infarction|Diabetes Mellitus|Chronic Obstructive Pulmonary Disease|End-Stage Renal Disease
Interventions: BEHAVIORAL: Specialized Community Disease Management|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms and Efficacy of Dual Neurotechnology-aided Mirror Therapy in Chronic Stroke: Neural and Motor Plasticity, Movement Performance, Daily Function, and Quality of Life
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: DEVICE: transcranial direct current stimulation, tDCS|DEVICE: functional electrical stimulation, FES|OTHER: no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Angiography Characteristics of Patients With Surgically Closed Full-thickness Idiopathic Macular Holes < 600 μm With Air Versus 10% SF6 Tamponade
Status: COMPLETED
Conditions: Macular Holes|Optical Coherence Tomography
Interventions: PROCEDURE: Air|PROCEDURE: 10% SF6 and 90% air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Targeted Mass Drug Administration for Malaria in Ethiopia
Status: UNKNOWN
Conditions: Malaria
Interventions: OTHER: Treatment of positive individuals per national treatment guidelines|OTHER: Presumptive treatment with artemether-lumefantrine (AL) plus 14 days of primaquine (PQ)|OTHER: Optimized malaria control interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Validation of mμSORS for Noninvasive Blood Glucose Detection
Status: COMPLETED
Conditions: Diabetes Mellitus|Medical Device
Interventions: DEVICE: Multi-channel Microspatial Offset Raman Scattering Spectroscopy (mμSORS) for Noninvasive Blood Glucose Detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2a Study Followed to Evaluate the Safety, Tolerability and Levodopa Pharmacokinetics in Levodopa-treated Parkinson's Disease Patients Receiving ND0612
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Levodopa and carbidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Network of Trained Volunteers Automatically Activated, on the Reduction of the Start Time of Cardiopulmonary Resuscitation Maneuvers. Study Protocol.
Status: COMPLETED
Conditions: Cardio Respiratory Arrest
Interventions: OTHER: Training and creation of the Network-CPR|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Explorative Formulation of Insulin Degludec and Insulin Aspart Co-formulation Versus Explorative Formulation of Insulin Degludec and Insulin Aspart Separately Compared With Biphasic Insulin Aspart 30 in Male Subjects With Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart 30|DRUG: insulin degludec/insulin aspart 40|DRUG: insulin degludec/insulin aspart 50|DRUG: insulin degludec|DRUG: insulin aspart|DRUG: biphasic insulin aspart 30|DRUG: insulin degludec/insulin aspart 40|DRUG: insulin degludec/insulin aspart 50|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Ketones for Acutely Decompensated HEart Failure
Status: UNKNOWN
Conditions: Acute Heart Failure|Low Cardiac Output Syndrome|Hemodynamic Instability|Ketosis
Interventions: DIETARY_SUPPLEMENT: 25g Ketone monoester without added salts|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of Pressed BioHPP Polyether Ether Ketone (PEEK)-Based Versus Zirconia-Based Single Crowns
Status: UNKNOWN
Conditions: Clinical Performance|Patient Satisfaction
Interventions: OTHER: BioHPP PEEK single posterior crowns|OTHER: zirconia-based single posterior crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Preoperative Diets Before Bariatric Surgery
Status: UNKNOWN
Conditions: Morbid Obesity|Bariatric Surgery|Gastric Bypass
Interventions: DIETARY_SUPPLEMENT: Standard diet versus standard VLCD (Prodimed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Contraceptives After Administration of Semaglutide in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: placebo|DRUG: Microgyn®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appraisal of MDCO-157 and Plavix® Pharmacokinetics and Pharmacodynamics in Healthy Volunteers With an Evaluation
Status: COMPLETED
Conditions: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers
Interventions: DRUG: MDCO-157|DRUG: PLAVIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of HCC With Octanoate Breath Test vs. MRI Diagnosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DEVICE: ¹³C-Octanoate Breath Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Biliary Tract Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Liver Cancer|Pain
Interventions: DRUG: capecitabine plus gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cyclophosphamide and Docetaxel Every 3 Weeks as Neoadjuvant Therapy in Locally Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide and docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Social Cognition Training for Psychosis (SocialMind): A Feasibility Study
Status: COMPLETED
Conditions: Schizophrenia and Disorders With Psychotic Feature|Psychotic Episode
Interventions: BEHAVIORAL: SocialMind|BEHAVIORAL: Psychosocial treatment|DRUG: Psychotropic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCL
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: BIOLOGICAL: KW-0761|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial on Three Treatments for Scoliosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Scoliosis
Interventions: PROCEDURE: Hypercorrective night-time brace|BEHAVIORAL: Scoliosis specific exercises.|OTHER: Self-mediated physical activity.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietetic Effects of Mare's Milk in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: mare's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study to Evaluate the Safety and Efficacy of SSGJ-706 Monotherapy for Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors Patients
Interventions: DRUG: SSGJ-706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Luteolytic Effect of a Gonadotropin Releasing Hormone (GnRH) Agonist After the Administration of Human Chorionic Gonadotropin (hCG) in the Initial Follicular Phase a Its Influence on the Prognosis of in Vitro Fertilization Treatment
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: GnRH agonist|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potentiated Aminoglycosides in Postoperative Urinary Tract Infection Prophylaxis
Status: RECRUITING
Conditions: Urinary Tract Infections|Urological System Complication of Procedure
Interventions: COMBINATION_PRODUCT: mannitol-enhanced aminoglycoside|DRUG: Ceftriaxon|DRUG: Amikacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1-2 Amrubicin in Combo With Lenalidomide + Weekly Dexamethasone in Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Amrubicin|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Aspirin|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination for the Treatment of Previously Untreated or Relapsed Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: BIOLOGICAL: Lethally Irradiated Lymphoma cells with GM-CSF K562 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infliximab for Treatment of Axial Spondyloarthritis (P05336 AM1)
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Axial Spondyloarthritis
Interventions: DRUG: Infliximab|DRUG: Placebo|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Uproleselan|DRUG: Placebo|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study to Investigate the Food Effect of Lumacaftor in Combination With Ivacaftor
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: lumacaftor|DRUG: ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: An Effectiveness and Toxicity of CyberKnife Based Radiosurgery for Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: RADIATION: Radiosurgical thalamotomy|DRUG: CyberKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a 14-day Modified Sequential Therapy for Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: rabeprazole, amoxicillin, tetracycline, furazolidone (only for the first 7 days), colloidal bismuth pectin (for the second 7 days)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C-FLASH (Cigarillo Flavor and Abuse Liability, Attention, and Substitution in youtH)
Status: COMPLETED
Conditions: Smoking Behaviors
Interventions: OTHER: Aim 1: Online survey|BEHAVIORAL: Eye Tracking Activity|OTHER: Eye tracking survey|BEHAVIORAL: Online Experimental Marketplace (ETM)|OTHER: Aim 3 survey|OTHER: Cognitive Interviews|OTHER: Supplemental Aim 1 Interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combo-PEP: Multipurpose Prevention of Post-Exposure Prophylaxis Regimens
Status: COMPLETED
Conditions: Sexually Transmitted Diseases
Interventions: DRUG: Doxycycline|DRUG: Biktarvy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Exploratory Efficacy of HSC835 in Patients With Inherited Metabolic Disorders (IMD)
Status: WITHDRAWN
Conditions: Inherited Metabolic Disorders IMD
Interventions: DRUG: Umbilical cord blood transplantation with HSC835
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: AcrySof ReSTOR Aspheric IOL models SN6AD1 and SN6AD3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing the Gut Microbiota Alteration Associated With Severe Acute Malnutrition
Status: COMPLETED
Conditions: Severe Malnutrition|Malnutrition|Infant Nutrition Disorders|Child Nutrition Disorders|Kwashiorkor|Marasmus
Interventions: BIOLOGICAL: Stool samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phosphatidylcholine Supplementation in Infants
Status: WITHDRAWN
Conditions: Schizophrenia|Diminished P50 Sensory Gating
Interventions: DRUG: phosphatidylcholine supplementation|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pediatric Intubation During Resuscitation
Status: UNKNOWN
Conditions: Intubation|Resuscitation
Interventions: DEVICE: Shikani Optical Stylet|DEVICE: Endoeye Flexible Intubation (LF-V)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV A Bladder Cancer|Stage IV A Rectal Cancer|Stage IV B Colon Cancer|Stage IV B Rectal Cancer
Interventions: PROCEDURE: PET Scan|PROCEDURE: CT Scan|RADIATION: fludeoxyglucose F 18|PROCEDURE: computer-aided detection/diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation
Status: COMPLETED
Conditions: Growth Disorders|Intrauterine Growth Retardation
Interventions: DRUG: Genotonorm|DRUG: Genotonorm|DRUG: Genotonorm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralymphatic Immunotherapy in Increasing Doses, After Subcutaneous Immunotherapy
Status: COMPLETED
Conditions: Rhinitis, Allergic
Interventions: DRUG: ALK Alutard birch or 5-grasses|DRUG: ALK diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: An Efficacy Study
Status: NOT_YET_RECRUITING
Conditions: Brain Injuries, Traumatic|Wounds and Injury|Hemorrhage|Trauma Injury
Interventions: DRUG: Tranexamic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Three Different Formulations of Tenofovir 1% Gel When Administered Rectally
Status: COMPLETED
Conditions: HIV Prevention
Interventions: DRUG: Rectal formulation (RF) of tenofovir 1% gel|DRUG: Vaginal formulations (original VF and reduced vaginal glycerin formulation RGVF) of tenofovir 1% gel|DRUG: Universal HEC Placebo Gel Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Protective Effect of N-acetylcysteine on Early Outcomes of Deceased Renal Transplant
Status: UNKNOWN
Conditions: Renal Transplantation
Interventions: DRUG: N-acetylcysteine|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pain and Coordination Plan for Reduced Opioid Use After Accidental Injuries
Status: RECRUITING
Conditions: Opioid Use|Injury Traumatic|Pain, Postoperative
Interventions: OTHER: PAC-plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to See the Effects That a New Combination of the Three Drugs, Nab-paclitaxel, Gemcitabine, and Cisplatin Has on Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Biliary Tract Cancer
Interventions: DRUG: nab-paclitaxel in combination with gemcitabine + cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents
Status: AVAILABLE
Conditions: Fanconi Anemia|Autosomal or Sex Linked Recessive Genetic Disease|Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases.|Hematopoiesis Maintainance.
Interventions: GENETIC: human whole exome|GENETIC: whole genomic
Study Type: EXPANDED_ACCESS
Clinical trial: Deep Brain Stimulation in Treatment Resistant Schizophrenia
Status: COMPLETED
Conditions: Refractory Schizophrenia
Interventions: DEVICE: On-Stimulation|DEVICE: Off-Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
Status: RECRUITING
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Brexanolone Injection [Zulresso]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Appendiceal Adenocarcinoma|Intraperitoneal Paclitaxel
Interventions: DRUG: Dexamethasone|DRUG: Diphenhydramine|DRUG: Famotidine|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Status: RECRUITING
Conditions: Postoperative Analgesia|S-ketamine|Pediatrics|Caudal Block|Hypospadias
Interventions: DRUG: S-ketamine & Ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Carrageenan's Effect on Insulin Resistance in Humans
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Carrageenan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Status: TERMINATED
Conditions: Gestational Diabetes|Metformin|Treatment|Oxidative Stress
Interventions: DRUG: Metformin|DRUG: Rapid acting analog insulin Intermediate acting NPH Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Surgical Interventions to Assist Orthodontic Movement of Impacted Maxillary Canines
Status: COMPLETED
Conditions: Impaction of Tooth
Interventions: PROCEDURE: Corticotomy|PROCEDURE: Traditional withdrawal techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock
Status: UNKNOWN
Conditions: Septic Shock|Hyperlactatemia|Peripheral Perfusion
Interventions: OTHER: CRT guided resuscitation|OTHER: Lactate guided resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Berodual® Inhaled Via Respimat® Compared to MDI (Metered Dose Inhaler) in Pediatric Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Berodual® Respimat®, low dose|DRUG: Berodual® Respimat®, high dose|DRUG: Berodual® MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Performance of INVU™ Versus Intrauterine Pressure Catheter (IUPC) in Uterine Contractions Monitoring of Pregnant Women.
Status: COMPLETED
Conditions: Healthy, Pregnant Women
Interventions: DEVICE: INVU™|DEVICE: IUPC|DEVICE: TOCO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Compound Tripterygium Wilfordii Hook F for Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Active Rheumatoid Arthritis
Interventions: DRUG: Topical compound tripterygium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of the World Health Organization QualityRights Training in Italy
Status: RECRUITING
Conditions: Caregiver Burden
Interventions: OTHER: WHO QualityRights e-training|OTHER: Emotional intelligence e-training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perioperative Administration of Gabapentin for Reducing Inhalational Anesthetic Consumption
Status: UNKNOWN
Conditions: Gabapentin
Interventions: DRUG: oral gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SAFE-CRP: Structural Alterations and Function of Endothelium in Cardiovascular Risk Patients
Status: TERMINATED
Conditions: Hypertension|Coronary Arteriosclerosis
Interventions: DRUG: telmisartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nationwide Enhanced Implementation of Best Practices in Pancreatic Cancer Care (PACAP-1)
Status: COMPLETED
Conditions: Carcinoma, Pancreatic Ductal
Interventions: OTHER: Best practices in pancreatic cancer care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparable Effects of Lanreotide Autogel and Octreotide LAR on GH, IGF-I Levels and Patient Satisfaction
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide Autogel and Octreotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Gemcitabine and Carboplatin in Metastatic or Recurrent Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: 5-fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: DEVICE: speckle tracking echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dentists' Knowledge, Attitude and Practice Regarding Minimally Invasive Dentistry a Cross Sectional Comparative Study Between Two Governorates in Egypt
Status: NOT_YET_RECRUITING
Conditions: Attitude Towards Minimal Invasive Dentistry
Interventions: OTHER: Minimal invasive management of dental caries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal Changes in Muscle Mass After Intensive Care
Status: COMPLETED
Conditions: Critical Illness|Muscle Loss
Interventions: DEVICE: Muscle ultrasound|DEVICE: Indirect calorimetry|DIAGNOSTIC_TEST: Hand dynamometry|DIAGNOSTIC_TEST: MRC Sum Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and Blinatumomab in Treating Participants With Recurrent or Refractory Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: CD19 Positive|Philadelphia Chromosome Positive|Recurrent Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Blinatumomab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort Follow-up of Epidemic and Neuroimaging for Patients During the 1st Wave of the COVID-19 in China
Status: RECRUITING
Conditions: COVID-19|Post-COVID-19 Syndrome|Acute COVID-19|Post-Acute COVID-19
Interventions: DEVICE: Simultaneous cortico-spinal magnetic resonance imaging, Serum
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Interactive 3D Modelling to Improve Outcomes in Robotic-Assisted Partial Nephrectomy
Status: RECRUITING
Conditions: Kidney Tumor
Interventions: PROCEDURE: partial kidney nephrectomy|DEVICE: DaVinci Robot|DEVICE: Innersight 3D software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT