pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of SHR6390 Combined With Famitinib in the Treatment of HR + / HER2- Advanced Breast Cancer.
Status: UNKNOWN
Conditions: Advanced Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: SHR6390|DRUG: famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 131I-rituximab for Relapsed or Refractory Follicular or Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed or Refractory Follicular Lymphoma or Mantle Cell Lymphoma
Interventions: DRUG: 131I-rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: TETRAM 2. Treatment With Erythropoetin in Patients With Spinal Trauma With Neurological Deficit, Maximum Tolerated Dose Study
Status: WITHDRAWN
Conditions: Spinal Trauma With Neurological Deficit
Interventions: DRUG: Erythropoetin (rHuEPO, EPREX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Somatropin (Norditropin) in Insulin-like Growth Factor (IGF) Deficient Children
Status: COMPLETED
Conditions: Growth Hormone Disorder|Pituitary Dwarfism
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
Status: RECRUITING
Conditions: Diarrhea Infectious|Cholera
Interventions: BEHAVIORAL: Standard Recommendation|BEHAVIORAL: CHoBI7 Scale-Up Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) Regimens in Hospitalized Infants and Children Aged 28 Days to 36 Months Infected With Respiratory Syncytial Virus
Status: TERMINATED
Conditions: Respiratory Syncytial Viruses
Interventions: DRUG: Lumicitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Randomized, Open-Label, Crossover, PD/PK Study of a Novel Pram-Insulin Co-Formulation in Adults With T1D
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Insulin-dependent Diabetes Mellitus
Interventions: DRUG: PRAM9|DRUG: Regular Insulin + Pramlintide|DRUG: Regular Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Yoga for Postpartum Depression
Status: RECRUITING
Conditions: Mood Disorders
Interventions: BEHAVIORAL: Mindfulness-based yoga program|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With Symptomatic Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DRUG: Proellex 25 mg|DRUG: Proellex 50 mg|DRUG: Lupron Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 10mg
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: HCP1201 750/10mg|DRUG: Metformin SR 750mg|DRUG: Rosuvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupressure and Acustimulation Wrist Bands for the Prevention of Nausea and Vomiting Caused by Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: dolasetron mesylate|DRUG: granisetron hydrochloride|DRUG: ondansetron|DRUG: tropisetron|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PODER Familiar: Health Promotion for Latino Families of Children With IDD
Status: RECRUITING
Conditions: Health-Related Behavior|Quality of Life|Psychological Distress|Diet, Healthy|Physical Inactivity
Interventions: BEHAVIORAL: PODER Familiar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of [123I] MNI-187 and SPECT in Patients With Alzheimers Disease in Comparison to Healthy Subjects
Status: COMPLETED
Conditions: Alzheimers Disease
Interventions: DRUG: 123-I MNI-187 Injection and Imaging Procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dysport® Pediatric Lower Limb Spasticity Study
Status: COMPLETED
Conditions: Cerebral Palsy|Muscle Spasticity|Children
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vortioxetine (Lu AA21004) in the Prevention of Relapse of Major Depressive Episodes
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine (Lu AA21004)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-agent Capecitabine as Metronomic Chemotherapy in LAHNSCC (CMHN)
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation After Autologous HSCT in Patients With Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: allogeneic fecal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Different Ventilation Strategies in Infants Using the PLMA™
Status: COMPLETED
Conditions: Ventilation
Interventions: OTHER: Spontaneous ventilation|DEVICE: Pressure support ventilation|DEVICE: Pressure control ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Atorvastatin Versus Pravastatin on Platelet Inhibition by Clopidogrel
Status: COMPLETED
Conditions: Ischemic Heart Disease|Acute Coronary Syndromes
Interventions: DRUG: atorvastatin,pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Predictors and Longitudinal Neural Correlates of Deep Transcranial Magnetic Stimulation for Treating Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Deep Transcranial Magnetic Stimulation|DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
Status: RECRUITING
Conditions: DLBCL|Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Zilovertamab vedotin|BIOLOGICAL: Rituximab|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mineral Water Consumption on Serum Lipid Parameters
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Mineral water (Hita, Oita, Japan)|DIETARY_SUPPLEMENT: Mineral water (Aso-gun, Kumamoto, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ulcer Location and Debridement Frequency: Weekly vs. Biweekly Sharp Debridement in Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetic Foot|Wound Heal
Interventions: PROCEDURE: Conservative sharp debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of 50 mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women With Low Testosterone and HSDD
Status: NOT_YET_RECRUITING
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Oral Testosterone Undecanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study of Safety and Efficacy in Subjects Who Completed NEUROSTEM® Phase-I/IIa Clinical Trial.
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: human umbilical cord blood derived mesenchymal stem cells|OTHER: Normal saline 2mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Caries Prevention Based on Genetic Etiology and Risk.
Status: RECRUITING
Conditions: Caries,Dental
Interventions: OTHER: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH
Status: UNKNOWN
Conditions: Hypomineralization Molar Incisor
Interventions: OTHER: Use of fluoride toothpaste|RADIATION: Laser Therapy|PROCEDURE: Simulated Laser Therapy|PROCEDURE: Sealant application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Erythropoietin on Clinical Disability and Brain Pathology in Patients With Progressive Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis (Primary or Secondary Progressive Phase).
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neurofeedback in Cognitive Deficit in Patients With TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: LoRETA Z-score NF|BEHAVIORAL: theta/beta NF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Subcostal TAP Block
Status: COMPLETED
Conditions: Subcostal TAP Block for Multiport Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Ultrasound guided bilateral subcostal TAP block|PROCEDURE: Ultrasound guided bilateral posterior TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Xenaderm|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy for Malignant Disease
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Prehabilitation|PROCEDURE: Standard Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction
Status: COMPLETED
Conditions: Amyloid-beta
Interventions: DRUG: Sodium Oxybate|BEHAVIORAL: Sleep deprivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of Chiglitazar Compare With Placebo in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Chiglitazar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Gliosarcoma
Interventions: DRUG: Avastin|DRUG: Temozolomide|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Synthetic Vaccine Derived From Plasmodium Vivax Circumsporozoite Protein (PvCS) in naïve and Semi-immune Volunteers
Status: UNKNOWN
Conditions: Malaria, Vivax
Interventions: BIOLOGICAL: Vaccine PvCS N+C+R 150 mcg|OTHER: Placebo SSN Montanide ISA-51 1 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Halifax PrenaBelt Trial
Status: COMPLETED
Conditions: Sleep|Pregnancy|Stillbirth|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Very Low Birth Weight|Fetal Growth Retardation|Fetal Hypoxia
Interventions: DEVICE: PrenaBelt|DEVICE: Sham PrenaBelt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel Strategies for Innovating Deceased Donor Procurement
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: PROCEDURE: Deceased donor nephrectomy, prior to cross clamp of donor aorta|PROCEDURE: Deceased donor nephrectomy, standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Lanreotide Autogel® 60, 90 or 120 mg With Lanreotide 40 mg Prolonged Release (PR) in Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide Autogel®|DRUG: Lanreotide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Selegiline in Treating Marijuana Dependent Individuals - 1
Status: COMPLETED
Conditions: Marijuana Abuse
Interventions: DRUG: Selegiline hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Carbo/cyclo|DRUG: Carbo/cyclo + atezolizumab|DRUG: Paclitaxel|DRUG: Paclitaxel + Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Golimumab Safety and Surveillance Program Using the Ingenix NHI Database
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Arthritis, Psoriatic|Ankylosing Spondylitis
Interventions: DRUG: systemic non-biological treatments|BIOLOGICAL: anti-TNF biologics|BIOLOGICAL: golimumab|BIOLOGICAL: non-anti-TNF biologics|OTHER: general population
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Functional Profiling in Metastatic Gastrointestinal Cancer or Recurrent Glioblastoma Patients in Luxembourg.
Status: RECRUITING
Conditions: Oncology
Interventions: DIAGNOSTIC_TEST: Personalized Functional Profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment Effectiveness of the Leap Motion Capture® System on the Functionality of the Upper Limb in Acquired Brain Injury
Status: UNKNOWN
Conditions: Stroke|Treatment Adherence|Patient Satisfaction|Brain Injuries, Traumatic
Interventions: OTHER: Conventional therapy|OTHER: Leap motion plus conventional therapya
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU
Status: TERMINATED
Conditions: Acute Kidney Injury
Interventions: DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Baby Books to Promote Maternal and Child Health
Status: COMPLETED
Conditions: Condition 1 - Educational Condition (Educational Book Group)|Condition 2 - Non-educational Condition (Non-educational Book Group)|Condition 3 - Control Condition (No-book Group)
Interventions: BEHAVIORAL: Educational Content/Pediatric Anticipatory Guidance|BEHAVIORAL: Book provision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Patient Satisfaction in Hepatitis C Patients Treated With PegIntron Pen and Rebetol in Romania (Study P04301)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031) pen|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
Status: RECRUITING
Conditions: Metastatic Neuroendocrine Prostate Cancer
Interventions: DRUG: [68Ga]Ga-PSMA-11|DRUG: [68Ga]GA-DOTA-TATE|DRUG: [68Ga]Ga-NeoB|DRUG: [177Lu]Lu-PSMA-617|DRUG: [177Lu]Lu-DOTA-TATE|DRUG: [177Lu]Lu-NeoB|DRUG: L-Lysine HCl-L-Arginine HCl, 2.5 %,|DRUG: Gonadotropin-releasing hormone (GnRH) analogues|DRUG: GnRH antagonists|DRUG: Antiemetics & antinauseants|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Surgery Versus Radiofrequency Ablation for Recurrent HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Laparoscopic Surgery(LS)|PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-VEC in Non-melanoma Skin Cancer
Status: COMPLETED
Conditions: Non-melanoma Skin Cancer|Basal Cell Carcinoma|Squamous Cell Carcinoma|Cutaneous Lymphoma|Merkel Cell Carcinoma
Interventions: GENETIC: Talimogene Laherparepvec (T-VEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epstein Barr Virus (EBV) Specific Cytotoxic T-Cells, Relapsed Lymphoma, ANGEL
Status: COMPLETED
Conditions: Epstein-Barr Virus-Related Hodgkin Lymphoma|Epstein-Barr Virus-Related Non-Hodgkin Lymphoma|EBV Positive Plasma Cell Neoplasm
Interventions: BIOLOGICAL: Injection of EBV Specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging of Human Hypothalamic Responses to Oral Temperature and Glucose Sensing
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: water 0|OTHER: water 22|OTHER: Glucose 0|OTHER: Glucose 22
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: OIT and Xolair® (Omalizumab) in Cow's Milk Allergy
Status: COMPLETED
Conditions: Milk Allergy
Interventions: BIOLOGICAL: Placebo for omalizumab|BIOLOGICAL: Omalizumab|DRUG: Milk powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition Of Exenatide To Insulin Glargine In Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: placebo|DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botox Injection in Treatment of Cluster Headache
Status: COMPLETED
Conditions: Cluster Headache
Interventions: DRUG: Botulinum Toxin Type A 25 IU|DRUG: Botulinum Toxin Type A 50 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurological Recovery Following NOS-SACD
Status: NOT_YET_RECRUITING
Conditions: Nitrous Oxide Abuse|Subacute Combined Cord Degeneration|Neurologic Symptoms|Paresthesia|B12 Deficiency Vitamin
Interventions: OTHER: Observational study with no interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nanogen Pegcyte Clinical Study for the Prevention of CIN in Breast-cancer Patients.
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: pegcyte|DRUG: Neulastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacies of Tetracycline-levofloxacin, Standard Bismuth, Amoxicillin-levofloxacin Quadruple Therapy for H.p
Status: RECRUITING
Conditions: Helicobacter Pylori Eradication
Interventions: DRUG: esomeprazole, tripotassium dicitrate bismuthate, tetracycline and levofloxacin|DRUG: esomeprazole , tripotassium dicitrate bismuthate, tetracycline 500mg and metronidazole|DRUG: esomeprazole, tripotassium dicitrate bismuthate , amoxicillin and levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Solid Neoplasm|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Unresectable Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacogenomic Study|OTHER: Pharmacological Study|DRUG: Topotecan Hydrochloride|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conjugated Hyperbilirubinemia and Pulse Oximetry
Status: TERMINATED
Conditions: Liver Disease|Hyperbilirubinemia
Interventions: PROCEDURE: Arterial Blood Gas|PROCEDURE: Pulse Oximetry Machine|PROCEDURE: Direct and Indirect Serum Bilirubin Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: cisplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users
Status: RECRUITING
Conditions: Abnormal Uterine Bleeding|Tranexamic Acid|Estrogen|Depot Medroxyprogesterone Acetate
Interventions: DRUG: Tranexamic acid 250 mg oral tablet|DRUG: Progynova 1 mg oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Machine-Learning Based EEG Biomarkers for Personalized Interventions
Status: RECRUITING
Conditions: Neuropathic Pain|Spinal Cord Injuries|Central Neuropathic Pain
Interventions: DEVICE: transcranial Direct Current Stimulation|DIAGNOSTIC_TEST: Electroencephalography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: Mepilex Transfer Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dural Puncture Epidural Technique For Vaginal Procedures
Status: COMPLETED
Conditions: Gynecologic Diseases Requiring Vaginal Hysterectomy
Interventions: PROCEDURE: Conventional Epidural Technique|PROCEDURE: 25G Dural Puncture Epidural Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Adalimumab Treatment for Induction and Maintenance of Clinical Remission in Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia
Status: RECRUITING
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Myocardial Ischemia|Hypoxia
Interventions: PROCEDURE: Discontinued ventilation|PROCEDURE: Continued ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Cyclosporine ImpRove Clinical oUtcome in ST Elevation Myocardial Infarction Patients at 3 Years of Follow-up. CIRCUS II Study
Status: COMPLETED
Conditions: ST Elevation Acute Myocardial Infarction
Interventions: DRUG: Injection of Cyclosporin|DRUG: Placebo|PROCEDURE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Effects of Calcium on the Gut-Bone Axis
Status: COMPLETED
Conditions: Healthy|Adult|Calcium|Bone Resorption|Endocrine; Obesity
Interventions: DIETARY_SUPPLEMENT: Calcium carbonate|DIETARY_SUPPLEMENT: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Effects of Lanthanum Carbonate Versus Calcium Acetate Versus Dietary Phosphorus Restriction
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: OTHER: Diet counseling|OTHER: Diet counseling|DRUG: Phosphorus binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Tipranavir (TPV)/Ritonavir (RTV) at Steady State Administered as Oral Solutions vs. Capsules in the Fed and Fasted State in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TPV capsule|DRUG: TPV solution|DRUG: RTV capsule|DRUG: RTV solution|OTHER: standard meal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rocuronium Consumption in Etomidate-based and Propofol-based General Anesthesia Under Sevoflurane
Status: COMPLETED
Conditions: Neuromuscular Monitoring
Interventions: DRUG: MAC 0.5|DRUG: MAC 0.75|DRUG: MAC 1.0|DRUG: Propofol|DRUG: Etomidate|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Ruxolitinib|DRUG: Capecitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: CE-mark approved LAA closure devices|DRUG: Acetylsalicylic acid|DRUG: Clopidogrel|DRUG: Dabigatran|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Edoxaban|DRUG: Phenprocoumon|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Regulation of Lipoprotein Transport in Metabolic Syndrome
Status: COMPLETED
Conditions: Obesity|Lipid Disorders|Cardiovascular Disease
Interventions: DRUG: GW501516|DRUG: placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Incidence of Febrile Episodes During Stem Cells Collection After Chemotherapy in Patients With Multiple Myeloma
Status: UNKNOWN
Conditions: G-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim
Interventions: DRUG: filgrastim|DRUG: lenograstim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral Halitosis
Status: COMPLETED
Conditions: Halitosis
Interventions: OTHER: Toothpaste with curcumin|OTHER: Toothpaste without curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Assessing Roux-en-Y Anastomosis of the Pancreatic Stump to Prevent Pancreatic Fistula Following Distal Pancreatectomy
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Cystic Lesions|Chronic Pancreatitis|Pancreatic Neuroendocrine Tumors|Pancreatic Pseudocysts
Interventions: PROCEDURE: Stapling closure of the pancreatic stump|PROCEDURE: Roux-en-Y anastomosis of the pancreatic stump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Three-Dimensional Vascular Reconstruction of the Pancreas on Multidetector Computed Tomography Images and Its Impact on Patients Undergoing Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Pancreaticoduodenectomy
Interventions: PROCEDURE: Pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effects of Implanted (Autologous) Skeletal Myoblasts (MyoCell) Using an Injection Catheter = SEISMIC Trial
Status: UNKNOWN
Conditions: Myocardial Infarction|Heart Failure, Congestive
Interventions: PROCEDURE: Myoblasts injection with MyoCath catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Combination With Dinaciclib (MK-7965) in Hematologic Malignancies (MK-3475-155/KEYNOTE-155)
Status: TERMINATED
Conditions: rrCLL|rrMM|rrDLBCL
Interventions: BIOLOGICAL: pembrolizumab|DRUG: dinaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Investigate the Efficacy and Safety of LN-OS-22 on Oxidative Stress and Systemic Inflammation in Overweight and Obese Population.
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: OTHER: LN-OS-22|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fentanyl vs Dexmedetomidine for Arthriscopic Shoulder Intervention in Elderly.
Status: COMPLETED
Conditions: Shoulder Lesions
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies (DLB)
Interventions: DRUG: Neflamapimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization (TACE) Plus Sorafenib Versus TACE for Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE+Sorafenib|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Nutritional Supplementation on Oxidative Stress in Protein-energy Wasting Patients With Peritoneal Dialysis
Status: UNKNOWN
Conditions: Oxidative Stress|Protein-Energy Wasting|Malnutrition|Protein-Energy Malnutrition|Oral Nutritional Supplements|Peritoneal Dialysis
Interventions: DIETARY_SUPPLEMENT: Oral nutritional supplementation for kidney disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Vaccine Targeting Brachyury Protein in Tumors
Status: COMPLETED
Conditions: Neoplasms|Malignant Solid Tumors|Colon Neoplasms|Adenocarcinoma
Interventions: BIOLOGICAL: GI-6301 (Yeast Brachyury Vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects
Status: UNKNOWN
Conditions: Non-invasive Ventilation|Healthy Subjects
Interventions: DEVICE: Non-invasive high-frequency oscillatory ventilation|DEVICE: Noninvasive Bilevel Positive Pressure Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pattern Of Isolated Fungi From Bronchoalveolar Lavage Among Patients With Bronchial Asthma
Status: NOT_YET_RECRUITING
Conditions: Bronchial Asthma
Interventions: DEVICE: fibroptic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ALT-FLOW II Trial of the Edwards APTURE Transcatheter Shunt System
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Edwards APTURE transcatheter shunt system|DIAGNOSTIC_TEST: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone|DRUG: Dexamethasone and droperidol|DRUG: Dexamethasone and Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Influenza Vaccination in Patients With Coronary Artery Diseases
Status: COMPLETED
Conditions: Coronary Artery Diseases|Myocardial Infarction|Stable Angina
Interventions: BIOLOGICAL: influenza vaccine|BIOLOGICAL: placebo for influenza vaccine|BIOLOGICAL: influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Propofol Versus Sevoflurane Anesthesia in Pediatric Strabismus Surgery: Feasibility of BIS Monitoring
Status: COMPLETED
Conditions: Strabismus
Interventions: DEVICE: Bispectral Index Monitor|DEVICE: Laryngeal Mask Airway|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Electrical Stimulation-guided Epidural Analgesia for Vaginal Delivery
Status: UNKNOWN
Conditions: Epidural Analgesia
Interventions: DEVICE: Epidural electrical stimulation (EES)|DEVICE: Loss of resistance (LOR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Off-Label AVASTIN (BEVACIZUMAB) For Serosanguinous Maculopathy
Status: UNKNOWN
Conditions: Choroidal Neovascularisation|Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Bevacizumab (tradename: Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to Recombinant Live-Attenuated Parainfluenza Type 1 Virus Vaccine
Status: COMPLETED
Conditions: Parainfluenza|Virus Diseases
Interventions: BIOLOGICAL: rHPIV1 84/del170/942A, Lot PIV1 #104A vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Performance of Long-wavelength Autofluorescence Imaging
Status: COMPLETED
Conditions: Retinal Disease|Retinal Degeneration|Retinal Dystrophies
Interventions: DEVICE: Long-wavelength autofluorescence imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Ultrasound Guided Femoral Nerve Block on Isolated Femur Fracture Using Echo Friendly Needles
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Femoral Nerve Block|DEVICE: Echogenic needle|DEVICE: Standard of care needle|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and Digoxin
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AZD5462|DRUG: Midazolam|DRUG: Rosuvastatin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Trametinib|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Endothelial Cell Activation and Modifications of Haemostasis Induced by Infective Endocarditis on the Risk of Embolism
Status: COMPLETED
Conditions: Infective Endocarditis
Interventions: OTHER: ULTRASONOGRAPHY trans-esophageal and trans-thoracic , blood test and clinic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma
Status: RECRUITING
Conditions: Kaposi Sarcoma
Interventions: DRUG: NHS-IL12|DRUG: M7824
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Microfracture Procedure on Rotator Cuff Tendon Healing
Status: SUSPENDED
Conditions: Rotator Cuff Tears|Micro Fracture
Interventions: PROCEDURE: Microfracture + Standard Arthroscopic Rotator Cuff Repair|PROCEDURE: Standard Arthroscopic Rotator Cuff Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT)
Status: TERMINATED
Conditions: HIV Prevention
Interventions: DRUG: Q-Griffithsin (Q-GRFT) enema|OTHER: Placebo enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Shoulder Intra-Articular Ozone Injection Versus Pulsed Radiofrequency Application for Shoulder Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis|Shoulder Pain
Interventions: PROCEDURE: Steroid Group|PROCEDURE: Ozone Group|PROCEDURE: PRF Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Patients With Non-Small Cell Lung Cancer Testing If Erlotinib Plus SU011248 (Sunitinib) Is Better Than Erlotinib Alone
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: erlotinib|DRUG: sunitinib|DRUG: erlotinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polyphenols Supplementation on Prostaglandin E2 in Women - Randomized Clinical Trial
Status: COMPLETED
Conditions: Inflammatory Disorder of the Cardiovascular System
Interventions: DIETARY_SUPPLEMENT: Polyphenols|DIETARY_SUPPLEMENT: Placebo controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MnSOD (Esophageal Protectant) to Prevent Esophagitis During Radiation/Chemotherapy Treatment for Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Esophageal|Toxicity
Interventions: GENETIC: Manganese Superoxide Dismutase Plasmid Liposome|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Intracranial Atherosclerotic Disease|Stroke|Angioplasty, Balloon|Hemodynamics|Device Safety
Interventions: DEVICE: Submaximal balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: PROCEDURE: Prolonged Exposure|PROCEDURE: Present Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Investigation of Novel Nano-vesicles of Salbutamol Sulphate
Status: COMPLETED
Conditions: Drug Effect|Pulmonary Disease
Interventions: DRUG: Salbutamol Sulphate|DRUG: Niosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies
Status: TERMINATED
Conditions: Sickle Cell Anemia|Hemoglobinopathy|Thalassemia
Interventions: DRUG: FLUDARABINE|DRUG: CAMPATH-IH|PROCEDURE: Total Body Irradiation|DRUG: FK506|DRUG: G-SCF (Granulocyte-colony stimulating factor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Tadalafil and Gastric Emptying Time in Diabetic Gastroparesis
Status: WITHDRAWN
Conditions: Gastroparesis|Diabetic Gastroparesis|Nausea|Vomiting
Interventions: DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Treatment for Night-Eating Syndrome
Status: TERMINATED
Conditions: Night-eating Syndrome
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal and Systemic Vascular Resistance in Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Chronic Kidney Insufficiency|Hypertension|Vasodilation
Interventions: DRUG: Beta-blocker, ACE-inhibitor|DRUG: Calcium Channel Blockers, ACE-Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1701 in Combination With Gemcitabine and Albumin Paclitaxel in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: SHR-1701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT