pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Probiotics in Preventing Antibiotic Associated Diarrhoea Including Clostridium Difficile Infection
Status: COMPLETED
Conditions: Diarrhoea|Clostridium Difficile
Interventions: DIETARY_SUPPLEMENT: Probiotic drink containing the live strain|DIETARY_SUPPLEMENT: placebo probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coronary Artery Disease in Patients Suffering From Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Cardiovascular Disease
Interventions: OTHER: Illness history|OTHER: Measure of social conditions|OTHER: Measure of psychiatric condition|PROCEDURE: Cardiovascular measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect and Safety of the Four Points Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Liver Diseases|Adult Disease
Interventions: PROCEDURE: TAP|PROCEDURE: PVB|DRUG: Ropivacaine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of EN3348 (Mycobacterial Cell Wall-DNA Complex [MCC]) as Compared With Mitomycin C in the Intravesical Treatment of Subjects With BCG Recurrent/Refractory Non-muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Bladder Neoplasm|Neoplasm Recurrence, Local|Transitional Cell, Carcinoma|Carcinoma in Situ|Mycobacterium
Interventions: BIOLOGICAL: EN3348|BIOLOGICAL: Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture for Dysmenorrhea Secondary to Adenomyosis
Status: NOT_YET_RECRUITING
Conditions: Dysmenorrhea|Adenomyosis|Electroacupuncture
Interventions: DEVICE: Electroacupuncture|DEVICE: Sham Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Cardiovascular Health Promotion Program in Youth - The Tyrolean Early Vascular Ageing-study
Status: COMPLETED
Conditions: Atherosclerosis|Life Style
Interventions: BEHAVIORAL: Multi-layer health promotion program|OTHER: Standard health education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microwave Ablation Combined With Chemotherapy in the Treatment of Pancreatic Cancer Oligohepatic Metastasis
Status: UNKNOWN
Conditions: Pancreatic Cancer Metastatic to Liver|Oligometastasis
Interventions: COMBINATION_PRODUCT: Microwave Ablation combination with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients.
Status: UNKNOWN
Conditions: Acute Kidney Injury|Hemodialysis
Interventions: DRUG: Unfractionated heparin|DRUG: Citrasate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EDMONd - Elemental Diet in Bowel Obstruction
Status: UNKNOWN
Conditions: Ovarian Cancer|Ovarian Neoplasms|Ovarian Disease|Peritoneal Neoplasms|Peritoneal Diseases|Metastatic Ovarian Cancer|Primary Peritoneal Carcinoma|Abdominal Neoplasm|Bowel Obstruction
Interventions: DIETARY_SUPPLEMENT: Elemental 028 Extra Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Connective Tissue Massage in Women With Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: BEHAVIORAL: pelvic floor exercise and connective tissue massage|BEHAVIORAL: pelvic floor exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of SARS-CoV-2 on the Central Nervous System and One-year Follow-up of "Long COVID-19" Patients
Status: UNKNOWN
Conditions: Long Covid19
Interventions: DIAGNOSTIC_TEST: Perfusion brain scintigraphy imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 12 Weeks of Hemodialysis With Medium Cut-Off Filter Compared to Hemodiafiltration With Standard High-flux Filter.
Status: WITHDRAWN
Conditions: Chronic Kidney Diseases|Uremia
Interventions: DEVICE: MCO-HD|DEVICE: high-flux HDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Recombinant SARS-CoV-2 Vaccine (CHO Cell) for COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: low-dose Recombinant SARS-CoV-2 Vaccine (CHO cell)|BIOLOGICAL: high-dose Recombinant SARS-CoV-2 Vaccine (CHO cell)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Glufosfamide|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relevance of [68Ga]Ga -PentixaFor-PET for Initial Staging and Therapeutic Evaluation of Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: [68Ga]Ga-PentixaFor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
Status: COMPLETED
Conditions: Critically Ill|Acute Respiratory Failure
Interventions: OTHER: PSV ventilation strategy|OTHER: PAV+ ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of LD013 in Subjects With Refractory or Relapsed Mesothelin -Positive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: mesothelin-specific chimeric antigen receptor T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-10380 in Chinese Participants
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: HS-10380|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Drugs in the Prevention of Tooth Sensitivity Caused by Tooth Bleaching Treatment.
Status: COMPLETED
Conditions: Hydrogen Peroxide Allergy
Interventions: DRUG: acetam/ketoro tromet group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Post Cesarean Section Analgesic Effect of Various Quadratus Lumborum Block Approaches
Status: COMPLETED
Conditions: Painless Labor|Epidural Analgesia|Cesarean Section
Interventions: PROCEDURE: Epidural analgesia (EA) only group|PROCEDURE: Quadratus lumborum block (QL2)|PROCEDURE: Quadratus lumborum block 3(QL3)|PROCEDURE: Quadratus lumborum block 2+3 QL(2+3)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of RAD001 in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor
Status: COMPLETED
Conditions: Lung Neuroendocrine Neoplasm
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibitors on Islet Cell Function and Insulin Sensitivity in Patients of Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Empagliflozin|DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Administration of Carnitine in sEpsis
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Levo-Carnitine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postural Garment Versus Exercises for Women With Cervical Pain
Status: COMPLETED
Conditions: Posture|Cervical Pain
Interventions: OTHER: Exercises|DEVICE: Posture garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine the Dose of BI 836826-GemOx and the Efficacy of BI 836826-GemOx Versus R-GemOx in Patients With Relapsed/Refractory DLBCL
Status: COMPLETED
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: BI 836826|DRUG: GemOx|DRUG: Rituximab|DRUG: GemOx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending-Dose Study of XmAb®27564 in Patients With Psoriasis or Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis|Atopic Dermatitis
Interventions: BIOLOGICAL: XmAb27564|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety and Efficacy of Tregalizumab in Subjects (MTX-IR) With Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tregalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
Status: RECRUITING
Conditions: Wrist Disease|Hand Injuries|Wrist Injuries|Hand Disease|Hand Injuries and Disorders
Interventions: DRUG: Placebo|DRUG: 0.1mg/kg Dexamethasone|DRUG: 0.05mg/kg Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser and High Intensity Tesla Magnetic Stimulation (HITS) for Stress Urinary Incontinence (SUI)
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: laser and High intensity Tesla magnetic stimulation|DEVICE: laser (without HITS treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Mild Cognitive Impairment in Early Recovery Stage After Ischemic Stroke
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Ischemic Stroke
Interventions: DRUG: MMH-MAP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ipragliflozin L-proline|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INTERVAL: Varying Intervals of ART to Improve Outcomes in HIV
Status: TERMINATED
Conditions: HIV-1-infection
Interventions: OTHER: Three-month ART dispensing|OTHER: Six-month ART dispensing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Modifying Young Adult Skin Cancer Risk and Protective Behaviors
Status: COMPLETED
Conditions: Melanoma and Other Malignant Neoplasms of Skin
Interventions: BEHAVIORAL: UV4.me2|BEHAVIORAL: UV4.me|BEHAVIORAL: E-Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intermittent Oral-esophageal Tube Feeding in Alzheimer's Patients With Dysphagia
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Conventional Care|DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: Nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Persistent or Recurrent Clear Cell Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Clear Cell Adenocarcinoma|Recurrent Ovarian Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing Novel Dipole Density Capabilities to Objectively Visualize the Etiology of Rhythms in Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: AcQMap System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort
Status: COMPLETED
Conditions: Colic
Interventions: DRUG: Hyoscine butylbromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: isolated limb perfusion|PROCEDURE: conventional surgery|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Correlation of Endothelial Function and Early Coronary Artery Disease in Humans
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DRUG: Atrasentan|DRUG: Atrasentan|DRUG: atrasentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Polatuzumab Vedotin|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Vincristine Placebo|DRUG: Prednisone|DRUG: Polatuzumab vedotin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I3LTE4: Intensive Insulin Therapy and Production of LTE4 in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Leucotrienes
Interventions: DRUG: intensive insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sublingual Misoprostol for Induction of Labor
Status: COMPLETED
Conditions: Labor|Induced
Interventions: DRUG: Misoprostol 25mcg|DRUG: Sublingual Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2).
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute Ischemic|Stroke, Acute
Interventions: DRUG: Intraarterial alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Relation Between Trigger Digit and Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: The Comorbidity Between the Trigger Digit and Carpal Tunnel Syndrome
Interventions: OTHER: Hybrid rehabilitation training|OTHER: Traditional rehabilitation training|OTHER: Wearable anti-bowstringing orthosis (WABO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Investigating Properties of the Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Recurrence After Thrombolysis in Acute Iliofemoral Venous Thrombosis (PRAIS) Study
Status: UNKNOWN
Conditions: Ileofemoral Deep Vein Thrombosis
Interventions: DRUG: rivaroxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Alirocumab on Postprandial Hyperlipemia in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Alirocumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Myolens CN (Central-Near) soft contact lens|DEVICE: MiSight® soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Obstructive Sleep Apnea (OSA), Sleepiness, and Activity in Diabetes Management
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Diabetes Mellitus, Type 2
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|DEVICE: Sham- Continuous Positive Airway Pressure (Sham-CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients
Status: COMPLETED
Conditions: Morbid Obesity|Surgery|General Anesthesia
Interventions: PROCEDURE: Higher PEEP|PROCEDURE: Lower PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Root Resorption During the Correction of Deep Bite With the Help of Laser Irradiation
Status: COMPLETED
Conditions: Deep Overbite
Interventions: DEVICE: Traditional orthodontic treatment|DEVICE: Low-Level Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Evaluation of Individual Placement and Support (IPS)
Status: COMPLETED
Conditions: Psychosis|Substance Abuse|Depression|Anxiety
Interventions: BEHAVIORAL: Individual Placement and Support|BEHAVIORAL: Ordinary employment schemes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a Self-management Oriented Diabetes Education Program for Intensified Insulin Therapy in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: MEDIAS 2 ICT|BEHAVIORAL: Current ICT program (ACC-ICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESBA1008 Microvolume Study
Status: COMPLETED
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: ESBA1008 solution|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Burkitt Lymphoma|Follicular Lymphoma|Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma
Interventions: DRUG: BTK inhibitor+ Fludarabine-based chemotherapy + CAR-T-CD19 Cells|DRUG: Fludarabine-based chemotherapy + CAR-T-CD19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations
Status: NOT_YET_RECRUITING
Conditions: Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: YK-209A tablet|DRUG: Pemetrexed+carboplatin/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High-intensity Interval Training on Low-grade Systemic Inflammation in Obese Young Adults.
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: OTHER: High-intensity Interval Training|OTHER: Moderate-intensity continuous training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Early Home-based Cardiac Rehabilitation Program for Patients After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BEHAVIORAL: entailing an early home-based CR program|OTHER: enter the usual care program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibutilide Administration During Pulmonary Vein Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Pulmonary Vein Ablation
Interventions: DRUG: Ibutilide fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Lidocaine and Esmolol on Attenuation of Hemodynamic Response to Orotracheal Intubation
Status: UNKNOWN
Conditions: Hemodynamic Instability
Interventions: DRUG: Esmolol|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychotherapy Outcome and Self-selection Effects in Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder (With or Without Agoraphobia)
Interventions: BEHAVIORAL: Panic Control Treatment (PCT)|BEHAVIORAL: Panic-Focused Psychodynamic Psychotherapy (PFPP)|OTHER: Waiting-list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Supplementation in Older Adults
Status: WITHDRAWN
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Treadmill Training and Whole-body Vibration in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Treadmill Training|OTHER: Whole Body Vibration & Treadmill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Storz CMAC Laryngoscope
Status: COMPLETED
Conditions: Intubation|Airway Management
Interventions: DEVICE: CMAC video laryngoscope|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remission Induction in Very Early Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept, methotrexate and depomedrone|DRUG: depemedrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Efficacy of Ultrasound Guided Rhomboid Intercostal Block Versus Serratus Anterior Plane Block for Mastectomy Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: rhomboid intercostal block|OTHER: serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Secukinumab in Japanese Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Secukinumab 150 mg provided in 1.0 mL pre-filled syringes (PFSs) for sc injection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL Amyloidosis
Status: COMPLETED
Conditions: AL Amyloidosis
Interventions: DRUG: Ixazomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis Who Participated in the MS-F204 Trial
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fampridine-SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of AZD5004 in Adults Who Are Living With Obesity or Overweight With at Least 1 Weight-related Comorbidity
Status: NOT_YET_RECRUITING
Conditions: Obesity or Overweight
Interventions: DRUG: AZD5004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of the Chartis System With Heterogeneous Emphysema Prior to Endobronchial Lung Volume Reduction (ELVR)
Status: COMPLETED
Conditions: Heterogeneous Emphysema
Interventions: DEVICE: Chartis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot Study
Status: TERMINATED
Conditions: Arthroplasty, Replacement, Knee|Pain, Postoperative
Interventions: GENETIC: Genetic Panel for Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Next Generation Sequencing-Based Stratification of Front Line Treatment of HighGrade Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Large-Cell Neuroendocrine Carcinoma
Interventions: OTHER: Treatment Specific for Non-Small Cell Carcinoma/Adenocarcinoma|OTHER: Treatment for Small Cell Lung Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Lipiodol Emulsion for the Embolization of Hypervascularizations in Patients With Knee Pain (LipioJoint1)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Honey Phonophoresis on Knee Cartilage Thickness
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Phonophoresis|DEVICE: Ultrasound|PROCEDURE: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage II Diffuse Large B-Cell Lymphoma|Ann Arbor Stage III Diffuse Large B-Cell Lymphoma|Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Rhinitis, Allergic, Nonseasonal
Interventions: BIOLOGICAL: MK-8237 tablets|BIOLOGICAL: Placebo tablets|DRUG: Rescue Medication: Self-Injectable Epinephrine|DRUG: Rescue Medication: Loratadine tablets|DRUG: Rescue Medication: Olopatadine ophthalmic drops|DRUG: Rescue Medication: Mometasone furoate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Flow Restriction Training on Tennis Elbow
Status: RECRUITING
Conditions: Tennis Elbow|Lateral Epicondylitis|Lateral Epicondylitis, Unspecified Elbow
Interventions: OTHER: Blood Flow Restriction Training|OTHER: Conventional Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Coronary artery bypass grafting (CABG)|PROCEDURE: Percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: YiQiFang|DRUG: YangYinFang|DRUG: YiQiYangYinFang|DRUG: placebo granules|DRUG: Erlotinib®|DRUG: Gefitinib®|DRUG: Icotinib®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Non-inferiority and Tolerability of the Device PHOS-ISTOS
Status: COMPLETED
Conditions: Keratosis, Actinic
Interventions: DEVICE: Aktilite® Galderma|DEVICE: PHOS ISTOS PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ZG005 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors
Interventions: BIOLOGICAL: ZG005 Powder for Injection|BIOLOGICAL: ZG005 Powder for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-surgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontal Diseases|Adverse Effects
Interventions: PROCEDURE: Supra/subgingival scaling using periodontal curette scraping|PROCEDURE: Supra and subgingival scaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rifabutin-containing Triple Therapy for Treatment of Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole|DRUG: Bismuth Potassium Citrate|DRUG: Tetracycline,Metronidazole|DRUG: amoxicillin rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: Cyclophosphamide|DRUG: Psoralen|DRUG: Thiotepa|PROCEDURE: Allogeneic bone marrow transplantation|PROCEDURE: In vitro-treated peripheral blood stem cell transplantation (PBSCT)|RADIATION: Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Large Volume Bupivacaine 0.5% Versus Small Volume in Elective Caesarean Section
Status: UNKNOWN
Conditions: Spinal Anesthesia
Interventions: DRUG: intrathecal 15 mg bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine and Huperzine A as Treatments for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence|Cocaine Addiction|Cocaine Abuse|Substance Abuse
Interventions: DRUG: Placebo|DRUG: Rivastigmine 3 mg|DRUG: Huperzine A 0.4 mg|DRUG: Rivastigmine 6 mg|DRUG: Huperzine A 0.8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: IVIG in Patients With VGKC Ab Associated Autoimmune Epilepsy
Status: TERMINATED
Conditions: Autoimmune Epilepsy
Interventions: DRUG: Intravenous Immunoglobulin|DRUG: Placebos|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars
Status: UNKNOWN
Conditions: Pulpitis - Irreversible|Resorption, Root|Abscess Bone|Mobility, Tooth|Pain
Interventions: DRUG: 70% Ethanol Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality Analgesia In Trauma Rehab
Status: UNKNOWN
Conditions: Virtual Reality|Musculoskeletal Pain|Opioid Use|Anxiety|Virtual Reality Analgesia|Trauma Injury
Interventions: OTHER: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of N1539 Following Major Surgery
Status: COMPLETED
Conditions: Pain, Post-operative
Interventions: DRUG: N1539|DRUG: Intravenous Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local and Systemic Tranexamic Acid on Edema and Ecchymosis in Orbital Surgery
Status: NOT_YET_RECRUITING
Conditions: Orbital Edema|Orbital Ecchymosis
Interventions: DRUG: Tranexamic acid injection|DRUG: Tranexamic Acid in NaCl,Iso-Os 1,000 Mg/100 mL (10 Mg/mL) INTRAVEN INTRAVENOUS SOLUTION, PIGGYBACK (ML)|DRUG: normal saline - injection|DRUG: normal saline - intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intracapsular Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults
Status: RECRUITING
Conditions: Tonsillar Hypertrophy|Sleep Apnea, Obstructive
Interventions: PROCEDURE: Tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Gemcitabine With Oxaliplatin as First Line Chemotherapy in Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Advanced Biliary Tract Adenocarcinoma|Gemcitabine|Oxaliplatin|Combination Chemotherapy|Efficacy
Interventions: DRUG: Gemcitabine and Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Do Adolescents and Adults Differ in Their Acute Response to Cannabis?
Status: COMPLETED
Conditions: Cannabis|Cannabis Intoxication|Cannabis Use|Cannabis Dependence|Marijuana|THC|CBD|Adolescent Development
Interventions: DRUG: Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)|DRUG: Cannabis with THC without CBD|DRUG: Placebo cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INSULIN GLARGINE (U300)|DRUG: metformin|DRUG: sulfonylurea|DRUG: meglitinides|DRUG: thiazolidinediones|DRUG: alpha-glucosidase inhibitors|DRUG: GLP1 Receptor Agonist|DRUG: Dipeptidyl peptidase-IV (DPP-IV) inhibitors|DRUG: Sodium-glucose transport-2 (SGLT-2) inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Cardiovascular Effects and Oxidative Status of Calcium and Vitamin D Supplementation of Postmenopausal Hypertensive Blacks Women
Status: COMPLETED
Conditions: Hypertension|Postmenopausal Disorder
Interventions: DIETARY_SUPPLEMENT: Calcium Arm|DIETARY_SUPPLEMENT: Vitamin D/Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HIV and Hepatitis Care Coordination in Methadone Treatment
Status: COMPLETED
Conditions: Hepatitis, Viral, Human|HIV Infections
Interventions: BEHAVIORAL: Testing, Education, & Counseling (TEC)|BEHAVIORAL: Hepatitis Care Coordination (HCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase II Study of VELCADE (Bortezomib) in Combination With Bendamustine and Rituximab in Subjects With Relapsed or Refractory Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: VELCADE|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Ergonomic Circadian Light on Hospitalized Stroke Patients in a Rehabilitation Unit
Status: COMPLETED
Conditions: Stroke|Sleep Apnea Syndromes|Depression|Anxiety
Interventions: DEVICE: Circadian Light luminaries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus Neutral-Zone CAD/CAM Dentures Restoring Mandibular Resorbed Ridges
Status: RECRUITING
Conditions: Denture, Complete
Interventions: DEVICE: CAD/CAM Milled Methacrylate Complete Removable Dentures based on bone-support concept.|DEVICE: CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Mirikizumab SC|DRUG: Mirikizumab IV|DRUG: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound Radiofrequency Ablation (EUS-RFA) of Not-resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DEVICE: EUSRA electrode needle connected to a radiofrequency generator (VIVA RF generator; STARmed, Seoul, S. Korea)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Study of BMF-500 in Adults With Acute Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Acute Mixed-Phenotype Leukemia
Interventions: DRUG: BMF-500
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening of Dysphagia Via Ultrasonography in Patients With Stroke
Status: COMPLETED
Conditions: Dysphagia, Oropharyngeal|Stroke
Interventions: DIAGNOSTIC_TEST: Ultrasonographic study|DIAGNOSTIC_TEST: Videofluoroscopic study temporal parameters|DIAGNOSTIC_TEST: Videofluoroscopic study distance parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: TMJ Pain
Interventions: DRUG: Vitamin C|OTHER: Injectable platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multi-institutional Study for Treatment of Children With Newly Diagnosed Hepatoblastoma Using a Modified PHITT Strategy
Status: RECRUITING
Conditions: Hepatoblastoma
Interventions: DRUG: Sodium Thiosulfate Injection|PROCEDURE: Primary surgery resection|DRUG: mono CDDP-Group A2|DRUG: Cisplatin, 5-Fluorouracil, Vincristine, Doxorubicin-Group C|PROCEDURE: Biopsy|PROCEDURE: Resection or transplant|PROCEDURE: Resection of pulmonary nodules|DRUG: mono CDDP- Group B|DRUG: Block 1 to 3 (Cisplatin, Doxorubicin) Group D|DRUG: Consolidation (Carboplatin, Doxorubicin) -Group D1|DRUG: Consolidation (Carboplatin +Doxorubicin/Vincristine + Irinotecan)-Group D2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and PharmacoDynamics of GW685698 in Paedeatric Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sarcoma Treatment Guide in Improving Self-Monitoring in Patients With Sarcoma Receiving Chemotherapy
Status: COMPLETED
Conditions: Sarcoma
Interventions: OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Exercise Trainings on Pain, Function and AHD in Patients With SPS
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Scapula Retraction Exercise Group|OTHER: Scapula Retraction +Glenohumeral Rotational Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staccato® Granisetron Single Dose PK
Status: COMPLETED
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: 0.5mg AZ-010|COMBINATION_PRODUCT: 1mg AZ-010|COMBINATION_PRODUCT: 3mg AZ-010|COMBINATION_PRODUCT: AZ-010 1mg|DRUG: IV Granisetron 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Selumetinib|DRUG: Moxifloxacin|DRUG: selumetinib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Seasonal Affective Disorder
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy (CBT-SAD)|OTHER: Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT