pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Guselkumab (TREMFYA) in Chinese Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PETRO Stroke Prevention in Patients With AF by Treatment With Dabigatran, With and Without Aspirin, Compared to Warfarin
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dabigatran with ASA|DRUG: dabigatran with ASA|DRUG: dabigatran with ASA|DRUG: dabigatran with ASA|DRUG: dabigatran with ASA|DRUG: dabigatran with ASA|DRUG: warfarin|DRUG: dabigatran without ASA|DRUG: dabigatran without ASA|DRUG: dabigatran without ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety, Tolerability, Immunogenicity, and Pharmacodynamic Study of SB12 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Progressive Core Stabilization Exercise Training
Status: COMPLETED
Conditions: Core Stability|Sports Physical Therapy|Adolescent|Sports Injury|Female Athlete
Interventions: OTHER: Progressive Core Stabilization Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cryoablation and RFA of Benign Thyroid Nodules: Pilot Study
Status: RECRUITING
Conditions: Benign Thyroid Nodule
Interventions: DEVICE: cryoablation|DEVICE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion
Status: RECRUITING
Conditions: Transfusion Related Complication
Interventions: DRUG: SNO|DRUG: Normal Saline|DRUG: Red Blood Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway
Status: COMPLETED
Conditions: Colorectal Disease
Interventions: DIETARY_SUPPLEMENT: Preoperative Oral Carbohydrate|DIETARY_SUPPLEMENT: Preoperative Oral Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing TPI-120 and Neulasta Administered Through Subcutaneous Route in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PEG-rhG-CSF|DRUG: Neulasta (PEG-rhG-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of tDCS to Enhance Virtual Reality Exposure Therapy Response in Acrophobia
Status: COMPLETED
Conditions: Acrophobia|Transcranial Direct Current Stimulation
Interventions: DEVICE: tDCS|BEHAVIORAL: virtual reality exposure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
Status: UNKNOWN
Conditions: Acute Pain|Pain, Postoperative
Interventions: PROCEDURE: Elbow Fracture Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Patients With Wet AMD
Status: COMPLETED
Conditions: Eye Diseases|Macular Degeneration|Retinal Diseases|Retinal Degeneration|Neovascularization, Pathologic
Interventions: DRUG: OPT-302|DRUG: Lucentis™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of a Heterologous Prime/Boost Vaccine Regimen of Ad26.Mos4.HIV and Aluminum Phosphate-Adjuvanted Clade C gp140 in Preventing Human Immunodeficiency Virus (HIV) -1 Infection in Women in Sub-Saharan Africa
Status: TERMINATED
Conditions: HIV-1
Interventions: BIOLOGICAL: Ad26.Mos4.HIV|BIOLOGICAL: Clade C gp140|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training and Metabolic Flexibility in Prediabetes
Status: TERMINATED
Conditions: PreDiabetes|Sedentary Lifestyle
Interventions: BEHAVIORAL: 6-week exercise training program|BEHAVIORAL: Standardized isoenergetic high fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
Status: COMPLETED
Conditions: Insulin Resistance|Prediabetic State
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Main Content of This Study is to Use Virtual Reality Technology Combined With Local Anesthesia With Lidocaine Injection at Different Times to Reduce the Pain of PICC in School-age Children
Status: COMPLETED
Conditions: Catheterization, Peripheral
Interventions: DEVICE: Virtual reality technology|OTHER: different timing of lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Suvorexant in Participants With Primary Insomnia - Study B (MK-4305-029)
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: DRUG: Suvorexant High Dose (HD)|DRUG: Suvorexant Low Dose (LD)|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Training and Cognitive Activity on the Mild Cognitive Impairment (MCI) Patient
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: OTHER: Physical Training and cognitive activity (EPC group)|OTHER: Physical training (EP group)|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum
Status: TERMINATED
Conditions: Sarcoma|Melanoma|Epithelial Malignancies|Pleural Malignancies
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Allogenic tumor Cell Vaccine (K562)|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary Hemochromatosis
Status: COMPLETED
Conditions: Iron Overload|Hereditary Hemochromatosis
Interventions: DRUG: Deferasirox (ICL670)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Level Laser Therapy on Hamstring Muscle Tightness and Calf Muscle Spasticity in Cerebral Palsy Children.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone or Interferon and/or Aldesleukin in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alpha-2a|DRUG: medroxyprogesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the QoL Improvement of Oral Oligo Fucoidan in Subjects Receiving Platinum-based Chemotherapy With NSCLC
Status: WITHDRAWN
Conditions: NSCLC Stage IV|NSCLC, Stage III
Interventions: DIETARY_SUPPLEMENT: Oligo Fucoidan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: iCOMtrain, Development and Evaluation of a Combined Training of Technical and Non-Technical Skills During the Management of Simulated Incidents in Intensive Care
Status: UNKNOWN
Conditions: Technical and Non-technical Training of Airway Management on ICU
Interventions: PROCEDURE: SAFE (situation, all together, fly on, evaluate)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails
Status: TERMINATED
Conditions: Onychomycosis
Interventions: DRUG: NAB001|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Maraviroc in Post-stroke Cognitive Impairment
Status: UNKNOWN
Conditions: Post Stroke Cognitive Impairment
Interventions: DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality to Cope With Academic Stress
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: Guided visualization of exams through immersive virtual reality|BEHAVIORAL: Guided visualization of exams through traditional method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Thymosin α1) V
Status: RECRUITING
Conditions: Acute Aortic Syndrome|Aortic Dissectio
Interventions: DRUG: Thymosin Alpha1, 28A-Glycine-28B-L-Arginine-28C-L-Glutamic Acid-28D-L-Alanine-28E-L-Proline-28F-L-Alanine-28G-L-Asparagine-|DRUG: Blank control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transforming Psychotherapy for Chronically Ill Patients
Status: COMPLETED
Conditions: Heart Failure, Congestive|Pulmonary Disease, Chronic Obstructive|Depression|Anxiety
Interventions: BEHAVIORAL: ACCES - Adjusting to Chronic Conditions with Education and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone 44 mcg|DRUG: Fluticasone 220 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Cutaneous Melanoma|Carcinoma, Renal Cell|Carcinoma, Ovarian Epithelial|Nasopharyngeal Carcinoma|Carcinoma, Thymic|Anal Cancer|Mesothelioma|Esophagogastric Cancer|High Microsatellite Instability Colorectal Carcinoma|Squamous Cell Carcinoma of Head and Neck|Triple Negative Breast Neoplasms
Interventions: DRUG: KFA115|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: placebo|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Misoprostol for Treatment of Postpartum Haemorrhage (PPH) in Home Births
Status: COMPLETED
Conditions: Postpartum Hemorrhage (PPH)
Interventions: OTHER: placebo|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Evoked Potentials With Modified Facilitation Technique
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: MEP using standard facilitation technique|DIAGNOSTIC_TEST: MEP using modified facilitation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Anti-allergic Effects of Specific Probiotics
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BEHAVIORAL: Probiotic or placebo yogurt consumed daily|DEVICE: Mini Rhinoconjunctivitis Quality of Life Questionnaire|PROCEDURE: Blood sample|PROCEDURE: Nasal lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Properties of CGRP and Cilostazol in Migraine Patients
Status: UNKNOWN
Conditions: Migraine|Migraine Without Aura|Migraine With Aura
Interventions: DRUG: Erenumab|DRUG: Placebo|DRUG: Calcitonin gene-related peptide|DRUG: Cilostazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Effect of Replacing Sugary Drinks by Low-sugar Alternatives on Body Weight and Fat Mass in Children
Status: COMPLETED
Conditions: Body Weight
Interventions: DIETARY_SUPPLEMENT: lemonade with sugar|DIETARY_SUPPLEMENT: lemonade low in sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Eco-guided PENS on Handgrip Strength
Status: COMPLETED
Conditions: Electrical Stimulation|Neuromodulation
Interventions: DEVICE: Eco-guided Percutaneous Electrical Stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy
Status: RECRUITING
Conditions: Cirrhosis, Liver|Hepatic Encephalopathy|Sarcopenia
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modified Application of Cardiac Rehabilitation for Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Cardiac Rehabilitation|Transition of Care
Interventions: BEHAVIORAL: MACRO-I|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Quality Improvement Project to Investigate Individual Provider Variation in Opioid Prescribing From the Emergency Department
Status: COMPLETED
Conditions: Analgesics, Opioid|Delivery of Health Care|Drug Prescribing|Over Prescribing|Prescribing Patterns, Physician|Practice Management, Medical|Practice Guidelines as Topic
Interventions: BEHAVIORAL: Individual prescribing data profile and self-assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) in Combination With Azacitidine for the Treatment of Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: G-CSF|DRUG: Plerixafor|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of XC8, Film-coated Tablets, 10 mg in Patients With Dry Non-productive Cough Against Acute Respiratory Viral Infection
Status: COMPLETED
Conditions: Common Cold|Acute Respiratory Infection|Influenza, Human
Interventions: DRUG: XC8, film-coated tablets, 20 mg/day|DRUG: XC8, film-coated tablets, 40 mg/day|DRUG: XC8, film-coated tablets, 80 mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pressure Enabled Drug Delivery By Pancreatic Retrograde Venous Infusion For Advanced Pancreatic Carcinoma
Status: WITHDRAWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: FOLFIRI|DRUG: FOLFIRINOX|DEVICE: TriSalus Infusion System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Initiation of Low Dose Tirofiban for PPCI in STEMI Patients.
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Tirofiban|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplantation in Treating Patients With Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Recombinant Interferon Alfa|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Mesna|PROCEDURE: Bone Marrow Transplantation|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Responses During Bilateral/Unilateral Sacral Nerve Stimulation for Idiopathic Faecal Incontinence
Status: COMPLETED
Conditions: Regional Cerebral Blood Flow|Fecal Incontinence
Interventions: DEVICE: Medtronic InterStim II - 3058
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Sutetinib Maleate Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patients (i.e. Patients Administered Thyrogen) Versus Hypothyroid Patients (no Thyrogen) Following 131I Administration
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: Thyrogen + Radioiodine (131I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Perception & Acceptability of a Cervical Cancer Prevention Prebiotic Device
Status: COMPLETED
Conditions: Sensory Perceptual Characteristics|User Acceptability of Gel Delivery System
Interventions: OTHER: PreBioGyn Gel|OTHER: Trimosan Gel|OTHER: RepHresh Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL
Status: UNKNOWN
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma|Philadelphia-Positive Acute Lymphoblastic Leukemia|ALL, Adult
Interventions: DRUG: dasatinib plus consolidation chemotherapy with vincristine and prednisone|DRUG: dasatinib plus consolidation chemotherapy with high-dose methotrexate and cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Study Probiotics on Body Fat Mass in Overweight and Obese Individuals Following Healthy Lifestyle Intervention
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Daily intake of study product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Repeated Sweet Breakfasts and Subsequent Sweet Food Preferences and Intakes
Status: COMPLETED
Conditions: Repeated Sweet Food Consumption
Interventions: BEHAVIORAL: Sweet food consumption|BEHAVIORAL: Non-sweet food consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pregnant Women Participating in Birth Preparation Training With Their Spouses on the Parenting Role, Attitudes of Their Spouses Towards Participating in the Birth, and Birth Self-Efficacy
Status: RECRUITING
Conditions: Birth Order|Parenting|Self Efficacy|Pregnancy Related
Interventions: OTHER: Birth Preparation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endovascular Treatment of Primary Common FEmoral Artery atheroSclerotic Disease wiTh IntraVAscular Litothripsy
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Common Femoral Artery Stenosis|Common Femoral Artery Occlusion|Critical Limb-Threatening Ischemia
Interventions: DEVICE: Intravascular litothripsy (IVL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Quizartinib|DRUG: Milademetan|DRUG: Milademetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate, Daunorubicin, and Cytarabine in Treating Patients With Relapsed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CDRM Study: Computer-assisted Diabetes Risk Management-for Secondary and Tertiary Prevention of T2DM Complications
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: PROCEDURE: risk profile information|PROCEDURE: standard DMP care|PROCEDURE: standard DMP care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Insulin Degludec With Insulin Glargine in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic/Pharmacokinetic Interactions Between Oral Roflumilast and Inhaled Formoterol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Roflumilast|DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Status: UNKNOWN
Conditions: Pemphigus|Bullous Pemphigoid|Stevens-Johnson Syndrome|Toxic Epidermal Necrolyses
Interventions: GENETIC: A single blood sample for HLA typing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Diagnostic and Prognostic Efficacy of MRI in Acute Sensorineural Hearing Loss and Ménière's Disease
Status: RECRUITING
Conditions: Sudden Sensorineural Hearing Loss|Meniere Disease|Ménière's Vertigo|Meniere's Disease Aggravated|Inner Ear Disease
Interventions: DIAGNOSTIC_TEST: Vestibular myogenic potentials
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive-Behavioral Bibliotherapy for the Treatment of Obsessive Compulsive Disorder in Children and Adolescents
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Bibliotherapy|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of "CD200" in Hematological Malignancies. Hematological Malignancies Comprise a Group of Malignant Clonal Disorders Arising From the Hematopoietic Tissues , Including Leukemia , Multiple Myeloma , and They Have a High Morbidity and Mortality
Status: NOT_YET_RECRUITING
Conditions: Hematological Malignancies
Interventions: DIAGNOSTIC_TEST: Flowcytometry on bone marrow aspiration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HBsAg Seroclearance in Adults With HBV Related Liver Fibrosis After Receiving Combined Therapy of Peg-IFN and Tenofovir.
Status: RECRUITING
Conditions: Liver Fibrosis
Interventions: DRUG: PEG-Interferon Alfa, Tenofovir Disoproxil Fumarate|DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Routine Assessment of Gastric Residuals in Preterm Neonates Influence Time Taken to Reach Full Enteral Feeding?
Status: COMPLETED
Conditions: Gastric Residuals Assessment|Prematurity|Sepsis Newborn|Necrotizing Enterocolitis of Newborn
Interventions: OTHER: No aspiration of gastric residuals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment
Status: TERMINATED
Conditions: Retinal Detachment
Interventions: DRUG: Dextenza|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extracorporeal Photopheresis and Mesenchymal Stem Cell Infusion for GVHD
Status: NOT_YET_RECRUITING
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Allogeneic mesenchymal stromal cells (MSCs)|BIOLOGICAL: Extracorporeal photopheresis (ECP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reaching a Caloric Goal Using a Gastric Sonar Versus Aspiration of Gastric Contents in Critically Ill Patients Receiving Nasogastric Enteral Nutrition
Status: NOT_YET_RECRUITING
Conditions: Enteral Nutrition Intolerance in Critically Ill Patients
Interventions: DIAGNOSTIC_TEST: Ultrasound assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Pilates on Balance and Spinal Curvature In Upper Crossed Syndrome
Status: COMPLETED
Conditions: Postural; Defect
Interventions: OTHER: Pilates exercises|OTHER: postural correction exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Six Week Efficacy, Safety and Tolerability Study of V565 in Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: V565|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Autosomal Dominant Cerebellar Ataxia
Status: COMPLETED
Conditions: Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia, Autosomal Recessive 3|Episodic Ataxia, Type 7
Interventions: OTHER: metabolic and imaging biomarkers in SCA1,2,3 and 7 patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photobiomodulation Before or After In-office Tooth Whitening for Sensitivity Reduction: a Blinded, Randomized, Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Tooth Sensitivity|Tooth Bleaching|Laser Therapy
Interventions: OTHER: Photobiomodulation with low power laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease
Status: TERMINATED
Conditions: Actinic Keratosis|Organ or Tissue Transplant; Complications
Interventions: DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LV Thrombus Screening in Anterior STEMI: Worth it?
Status: COMPLETED
Conditions: Thrombus of Left Ventricle|Anterior Wall Myocardial Infarction|ST Elevation Myocardial Infarction|Echocardiography
Interventions: OTHER: Contrast TTE procedure, the SonoVue ultrasound agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of POT PTCA Balloon Dilatation Catheter for the Optimal Dilation After DES Implantation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Balloon dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutrition and Oral Hygiene Education Using Telehealth on Diet Diversity, Nutrition Literacy and Oral Hygiene Practices in Children With Autism: A Mixed-method Study
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Educational
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Evaluation of a Honey Impregnated Dressing at Removing Necrotic Tissue From Chronic Wounds
Status: TERMINATED
Conditions: Wound Heal|Necrotic Tissue Removal
Interventions: DEVICE: Honey Impregnated Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS and tUS on Pain Perception in OA of the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Osteoarthritis
Interventions: DEVICE: active low-intensity transcranial electrical stimulation/active transcranial ultrasound|DEVICE: Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Gait Adaptation Due to an Asymmetric Walking Protocol
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Active Comparator: 0.25 m/s asymmetric session first|OTHER: Active Comparator: 0.50 m/s asymmetric session first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: Bendamustine hydrochloride|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adenotonsillectomy on Velopharyngeal Valve Mechanism
Status: RECRUITING
Conditions: Velopharyngeal Insufficiency
Interventions: PROCEDURE: adenotonsillectomy|PROCEDURE: adenoidectomy|PROCEDURE: tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Senior PAMI: Primary Angioplasty Versus Thrombolytic Therapy for Acute Myocardial Infarction in the Elderly
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Thrombolytic therapy|PROCEDURE: Percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Stroke
Interventions: DRUG: Rivaroxaban|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Inebilizumab and Rituximab in Neuromyelitis Optica Spectrum Disorders
Status: NOT_YET_RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorders
Interventions: DRUG: Inebilizumab|DRUG: Rituximab(RTX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subconjunctival Bevacizumab to Prevent Bleb Failure After Glaucoma Filtration Surgery
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Subconjunctival Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of MVA in Hematopoietic Stem Cell Transplant (HSCT) Subjects
Status: COMPLETED
Conditions: Variola Major (Smallpox)
Interventions: DRUG: Placebo|BIOLOGICAL: MVA-BN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Proton w/FOLFIRINOX-Losartan for Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: FOLFIRINOX|DRUG: Losartan|RADIATION: Proton Beam Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients
Status: COMPLETED
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome|Severe Sepsis|Septic Shock|Mechanical Ventilation
Interventions: OTHER: sRAGE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Study of a Computerized Cognitive Stimulation
Status: COMPLETED
Conditions: Mild Cognitive Impairment, So Stated
Interventions: BEHAVIORAL: Computerized Cognitive Stimulation|BEHAVIORAL: Multimedia-based internet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotic Blend in Reducing Anthropometric Measurements in Obese Adults
Status: RECRUITING
Conditions: Obesity|Obesity; Endocrine|Overweight and Obesity|Overweight, Obesity and Other Hyperalimentation
Interventions: DIETARY_SUPPLEMENT: Probiotic blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AMG 510|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV ΔNS2/Δ1313/I1314L|BIOLOGICAL: RSV 276|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Status: UNKNOWN
Conditions: Colon Adenoma|Colorectal Carcinoma|Hyperplastic Polyp|Serrated Adenoma
Interventions: DEVICE: NBI Function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Guselkumab in Participants With Systemic Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Scleroderma, Systemic
Interventions: DRUG: Guselkumab Dose 1|DRUG: Guselkumab Dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Teclistamab in Combination in Elderly Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Teclistamab|DRUG: Daratumumab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural Modulators of Immune Function and Mood
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Chaga Mushroom|DIETARY_SUPPLEMENT: Algae Extract|DIETARY_SUPPLEMENT: Black Cumin Seed Oil|DIETARY_SUPPLEMENT: Black Cumin Seed Oil + Astaxanthin|DIETARY_SUPPLEMENT: Black Cumin Seed Oil + Omega 3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Dendritic Cell Therapy for Hormone-Refractory Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Cancer
Interventions: BIOLOGICAL: Autologous dendritic cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study To Compare Pharmacokinietics Of 3 Different Formulations Of PF-04991532 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Formulation 1|DRUG: Formulation 2|DRUG: Formulation 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications
Status: COMPLETED
Conditions: Graft-Versus-Host Disease
Interventions: PROCEDURE: Bone Marrow Stromal Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Nivolumab in Patients With Unresectable Advanced/Metastatic Gastric Cancer and Gastroesophageal Junction Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Cancer
Interventions: DRUG: Nivolumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In Vivo EGFR-ECD Molecular Imaging Using [68Ga]- Labelling Anti-EGFR Affibody Molecule
Status: UNKNOWN
Conditions: Molecular Imaging
Interventions: OTHER: 68Ga-NODAGA-Ac-Cys-ZEGFR:1907
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Children With Relapsed or Refractory Acute Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: fludarabine phosphate|DRUG: idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Cinacalcet in Children With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hyperparathyroidism, Secondary|Secondary Hyperparathyroidism
Interventions: DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Deficiency Anemia (IDA) and the Brain
Status: RECRUITING
Conditions: IDA - Iron Deficiency Anemia|Anemia|Iron Deficiency Anemia|Anemia, Iron Deficiency
Interventions: DRUG: Ferric derisomaltose|DRUG: NovaFerrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Valproic Acid on Zidovudine Glucuronidation and Pharmacokinetics in HIV-Infected Patients.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Valproic acid|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Basis of Response to Vyvanse in Adults With ADHD: an fMRI Study of Brain Activation
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Lisdexamfetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Orthomolecular Therapy and Asthma in Children
Status: UNKNOWN
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Orthomolecular Therapy or Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TransMEM Gas Exchange -- Project 1, Aim 2
Status: COMPLETED
Conditions: Middle Ear Disease|Nasal Allergy
Interventions: BIOLOGICAL: ragweed|BIOLOGICAL: histamine|DRUG: pseudoephedrine|DRUG: Oxymetazoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Efficacy and Safety of Meloxicam vs. Diclofenac SR in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Diclofenac|DRUG: Meloxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of PEGylated Arginine Deiminase (ADI-PEG20) With Carboplatin and Cabazitaxel in Men With Aggressive Variant Prostate Cancers (AVPC)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: ADI-PEG 20|DRUG: Cabazitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate or Paclitaxel as First- or Second-Line Therapy in Treating Patients With Recurrent Stage IIIC-IV Breast Cancer
Status: SUSPENDED
Conditions: Breast Adenocarcinoma|HER2/Neu Negative|Invasive Breast Carcinoma|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Eribulin Mesylate|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Gastric Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: FPA144
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emoticare: Serious Game for the Adaptation to the Disease of Adolescents With Type 1 Diabetes Mellitus.
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes|Adolescent Development
Interventions: BEHAVIORAL: EmoTiCare
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Q-Griffithsin Intranasal Spray
Status: UNKNOWN
Conditions: COVID-19 Prevention
Interventions: DRUG: Q-Griffithsin 3.0|DRUG: Q-Griffithsin 6.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pemetrexed + Carboplatin + Bevacizumab + Enzastaurin Versus Pemetrexed + Carboplatin + Bevacizumab + Placebo in Participants With Non-Small Cell Lung Cancer Who Have Not Been Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: enzastaurin|DRUG: pemetrexed|DRUG: carboplatin|DRUG: bevacizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STaph Aureus Resistance-Treat Early and Repeat (STAR-TER)
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: Trimethoprim Sulfamethoxazole (TMP/SMX)|DRUG: Minocycline|DRUG: Mupirocin|DRUG: Chlorhexidine Gluconate|BEHAVIORAL: Environmental Decontamination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT