pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: INSPIRE: Internet and Social-media Program With Information and Resources for Long-Term Cancer Survivors Who Underwent Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer Survivor|Depression|Hematopoietic and Lymphoid Cell Neoplasm|Myelodysplastic Syndrome
Interventions: OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Medical Chart Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Androgen-Independent Prostatic Cancer|Androgen-Independent Prostatic Neoplasms|Prostate Cancer Recurrent|Androgen-Insensitive Prostatic Cance|Androgen-Resistant Prostatic Cancer|Hormone Refractory Prostatic Cancer|Immunotherapy|Immune Checkpoint Inhibitor|Inhibitory Checkpoint Molecule
Interventions: BIOLOGICAL: lorigerlimab|DRUG: docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intervention With Probiotic K56 on Body Fat Reduction in Obese Subjects
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Lactobacillus paracasei K56|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes With Electroconvulsive Therapy: Insights From Computational Modelling
Status: UNKNOWN
Conditions: Depression
Interventions: PROCEDURE: Brief Temporoparietal ECT|PROCEDURE: Ultrabrief Temporoparietal ECT|PROCEDURE: Brief Frontoparietal ECT|PROCEDURE: Ultrabrief Frontoparietal ECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure
Status: COMPLETED
Conditions: Opioid Use Disorder|Neonatal Abstinence Syndrome|Child Development|Child Abuse|Child Neglect
Interventions: BEHAVIORAL: RESPECT-Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Vascular Access for Radial and Femoral Completion of Diagnostic Cardiac Catheterization
Status: COMPLETED
Conditions: Ischemic Heart Diseases
Interventions: PROCEDURE: Radial Technical|PROCEDURE: Femoral Technical|DRUG: Omnipaque
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Venetoclax Combined With Azacitidine Regimen in Newly Diagnosed T-ALL Patients
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia|Recruiting
Interventions: DRUG: Venetoclax, Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Cerebrolysin|DRUG: 0.9% NaCl, saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: fMRI|DEVICE: Indirect calorimetry|DEVICE: Bioimpedance|BIOLOGICAL: Lipid profile, glucose, HBA1c, metabolomic analysis|BEHAVIORAL: YFAS questionnaire, Binge Eating Scale, Hospital Anxiety and Depression (HAD) scale, hedonic evaluation test (liking)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Treatment Adherence in HIV-Infected Individuals
Status: COMPLETED
Conditions: HIV Antiretroviral Therapy (ART) Adherence|Health Behavior
Interventions: BEHAVIORAL: LifeWindows Intervention Sessions|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Haloperidol for the Treatment of Headache in the ED
Status: COMPLETED
Conditions: Headache|Migraine Disorders
Interventions: DRUG: Haloperidol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones
Status: COMPLETED
Conditions: Choledocholithiasis|Large Common Bile Duct Stone
Interventions: PROCEDURE: ERCP|PROCEDURE: Endoscopic Sphincterotomy|DEVICE: Large Balloon Dilatation of Oddi Sphincter|PROCEDURE: Stone extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Concussion, Mild|Post-Concussion Symptoms|Sleep Problems
Interventions: DEVICE: wavelength-1 bright light|DEVICE: wavelength-2 bright light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Analysis of T-lymphocyte Subsets and Prognosis in Autologous Stem Cell Transplantation (ASCT) for Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Massage Ball Application on Blood Pressure, Fatigue and Anxiety in Pregnant With Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: OTHER: Massage Ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Nab-Paclitaxel and Gemcitabine and Plus/Minus VCN-01 in Patients With Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Metastatic
Interventions: DRUG: Nab-paclitaxel|DRUG: Gemcitabine|GENETIC: VCN-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Placebo for dexamethasone|DRUG: Placebo for rovalpituzumab tesirine|DRUG: Rovalpituzumab tesirine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain Metastases
Status: TERMINATED
Conditions: Melanoma (Skin)|Metastatic Cancer
Interventions: RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Quantitative Pregnancy Test in Amniotic Fluid as a Diagnostic Tool for Rupture of Fetal Membranes
Status: COMPLETED
Conditions: Premature Rupture of Membrane
Interventions: DIAGNOSTIC_TEST: assessment of beta subunit of human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjunctive Motivational Alcohol Intervention to Prevent IPV
Status: RECRUITING
Conditions: Alcohol Use and Intimate Partner Violence
Interventions: BEHAVIORAL: Motivational Enhancement Therapy|BEHAVIORAL: Alcohol Education Control|BEHAVIORAL: Treatment as Usual|BEHAVIORAL: Strength at Home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation and Skeletal Muscle Healing Process
Status: COMPLETED
Conditions: Skeletal Muscle Damage|Exercise-induced Aseptic Inflammation|Skeletal Muscle Performance|Intracellular Signaling in Skeletal Muscle|Proteasome Activation
Interventions: DIETARY_SUPPLEMENT: Milk protein isolate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intervention to Improve HIV Self-care Among People Who Inject Drugs
Status: RECRUITING
Conditions: Hiv|Substance Use Disorders
Interventions: BEHAVIORAL: Project iSTRIVE|BEHAVIORAL: incentivized Directly Observed Therapy (iDOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol Targets
Status: COMPLETED
Conditions: Hypercholesterolemia|HIV Infections
Interventions: DRUG: Ezetimibe|DRUG: Rosuvastatin (standard care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organ Interaction Patterns in Healthy Individuals for Improved PET/CT Diagnostics
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Siemens Quadra PET/CT and [18F]FDG|DEVICE: Apple i-Watch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Bicalutamide With Brain Re-irradiation to Treat Recurrent/Progressive High Grade Glioma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma|Recurrent High-grade Glioma
Interventions: DRUG: Bicalutamide|RADIATION: Intensity-modulated radiation therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PSMA Antagonist Produced by Two Different Methods
Status: COMPLETED
Conditions: Metastatic Prostate Adenocarcinoma
Interventions: DRUG: 68Ga-PSMA-generator vs. 68Ga-PSMA-cyclotron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of PEDAL Program With and Without EMS On Mobility And Gait In Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: PEDAL and EMS|OTHER: PEDAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Compare the Efficacy and Safety of Norspan to Tramadol/Acetaminophen With Prolonged Postoperative Pain (PASSION)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: buprenorphine|DRUG: tramadol/acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Pre-operative Anxiety of a Personalized Three-dimensional Kidney Model Prior to Nephron-sparing Surgery- Rein 3D Anxiety
Status: RECRUITING
Conditions: Tumoral Kidney
Interventions: OTHER: 3D model pré-operative education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome
Status: COMPLETED
Conditions: Acanthosis Nigricans|Polycystic Ovary Syndrome
Interventions: DRUG: leuprolide acetate|DRUG: spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Visumax Femtolasik Versus Moria M2 Microkeratome in Myopia
Status: COMPLETED
Conditions: Lasik in Myopia
Interventions: DEVICE: Visumax femtosecond laser|DEVICE: Moria M2 microkeratome (MK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: VFENDÂ® I.V., Oral|DRUG: Conventional amphotericin B|DRUG: Diflucan IV, oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real World Evaluation of the ELUVIA Stent in Subjects With Lesions Located in the Femoropopliteal Arteries
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Atherosclerosis|Vascular Diseases|Arteriosclerosis
Interventions: DEVICE: Peripheral stenting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Hydrogel Containing Cascade Catalytic Enzymes in the Treatment of Diabetic Wounds
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Wound
Interventions: DRUG: GAT@F nanoenzyme hydrogel complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool
Status: NOT_YET_RECRUITING
Conditions: Post-operative Complications
Interventions: OTHER: Epic Health Record cognitive aid|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interferon-gamma With Interferon Alpha and Ribavirin for Hepatitis C Non-responders
Status: COMPLETED
Conditions: Hepatitis C|Genotype 3|Non-responders|Relapsers
Interventions: DRUG: interferon alpha-2b, ribavirin, interferon-gamma,|DRUG: interferon alpha-2b, ribavirin, amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nitrogen Protoxide and Oxygen on Corneal Endothelial in Pediatric Patients
Status: COMPLETED
Conditions: Cornea|Anesthesia; Reaction
Interventions: OTHER: Nitrogen protoxide|OTHER: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers
Status: RECRUITING
Conditions: Kidney Stone
Interventions: DIETARY_SUPPLEMENT: Low Oxalate Diet before Weight Loss|DIETARY_SUPPLEMENT: Oral load of oxalate and sucralose before Weight Loss|DIETARY_SUPPLEMENT: Optifast VLCD Program|DIETARY_SUPPLEMENT: Optifast VLCD Transition Phase|DIETARY_SUPPLEMENT: Low Oxalate Diet after Weight Loss|DIETARY_SUPPLEMENT: Oral load of oxalate and sucralose after Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Dapagliflozin 10 MG Oral Tablet|DRUG: Metolazone Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PN 200 or Naproxen in Subjects Who Are at Risk for Developing NSAID-Associated Ulcers.
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Ankylosing Spondylitis
Interventions: DRUG: PN 200 tablets (500 mg naproxen and 20 mg omeprazole)|DRUG: Naproxen 500 mg tablets (PN 200 minus omeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Near Infrared Spectroscopy for Detection of Cerebral Desaturation After Positioning for Neurosurgical Procedures
Status: COMPLETED
Conditions: Cognitive Dysfunction|Patient Positioning
Interventions: OTHER: NIRS based protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Bone Marrow Stem Cells for Treating Chronic Renal Failure
Status: UNKNOWN
Conditions: Chronic Renal Failure
Interventions: OTHER: Autologous bone marrow stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-level Laser Therapy on Type II Controlled Diabetic Patients After Dental Implant Insertion
Status: COMPLETED
Conditions: T2DM (Type 2 Diabetes Mellitus)|Low-level Laser Therapy|Bone Density Increased
Interventions: RADIATION: low-level laser therapy (LLLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: ALS (Amyotrophic Lateral Sclerosis)
Interventions: BIOLOGICAL: MNC (Mononuclear cells)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: COMBINATION_PRODUCT: abaloparatide|COMBINATION_PRODUCT: abaloparatide solid microstructured transdermal system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Evaluating the Role of Surgeon-Performed Ultrasound in the Management of the Acute Abdomen
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: RADIATION: Surgeon-performed ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroesophageal Cancer|Immune Checkpoint Inhibition
Interventions: DRUG: Nivolumab|DRUG: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of The Musical Toy Used During Peripheral Vascular Access on Children's Pain, Fear And Parents' Satisfaction
Status: COMPLETED
Conditions: Pain|Child, Only|Parents
Interventions: DEVICE: Musical Toy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Fixed Dose Combination of Glimepiride and Metformin in Chinese Type 2 Diabetes Patients Inadequately Controlled With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glimepiride and Metformin hydrochloride combination (HOE490)|DRUG: Glimepiride (HOE490)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vatelizumab in Patients Who Completed Treatment in Study DRI13839
Status: TERMINATED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Vatelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacroiliac (SI) Screws: The Effect of SI Screw Removal on Patient-Reported Pain and Functional Outcomes
Status: COMPLETED
Conditions: Sacroiliac Joint|Pain|Pelvis
Interventions: PROCEDURE: SI Screw Removal Surgery|PROCEDURE: Non-screw removal treatment (non-operative management)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipragliflozin Add-on Long-term Study in Japanese Participants With Type 2 Diabetes Mellitus on Sitagliptin (MK-0431J-849)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ipragliflozin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release
Status: COMPLETED
Conditions: Anterior Knee Pain Syndrome
Interventions: DEVICE: Hyaluronic acid injection|DEVICE: No injection of Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Umbilical Cord Milking in Preterm Neonates With Placental Insufficiency
Status: COMPLETED
Conditions: Placental Insufficiency|Preterm Infant
Interventions: PROCEDURE: Umbilical Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACRYSOF® Restor Apodized Diffractive IOL Postmarket Evaluation of Clinical Outcomes and Life-Style Visual Performance RESTOR IOL SN60WF IOL (Control Group)
Status: WITHDRAWN
Conditions: Refractive Assessment
Interventions: PROCEDURE: Clinical visual outcomes of bilateral implantation of Restore Intra Ocular Lens.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib in Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors (GIST)
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis Of Knee
Interventions: DRUG: Etanercept|OTHER: Health education, exercise and diet guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema.
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Age Related Macular Degeneration
Interventions: DRUG: Ranibizumab Intravitreal injections
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Centered Occupational Therapy on Play Skills and Participation of Children With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Family-centered occupational therapy|BEHAVIORAL: regular occupational therapy|OTHER: intervention done outside our hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combined With Whole-body Hyperthermia to Treat Stage IIIB/IV Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage IIIB|Toxicity Due to Chemotherapy
Interventions: DEVICE: chemotherapy & WBH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physiotherapy Via Telerehabilitation in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19|Long COVID-19|Cardiopulmonary Function|Physical Function
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Herbal Supplements in Prediabetic and Mild to Moderate Hyperlipidemic Patients
Status: COMPLETED
Conditions: Prediabetes|Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Salacia bark extract|DIETARY_SUPPLEMENT: Salacia leaf extract|DIETARY_SUPPLEMENT: Sesame seed extract|BEHAVIORAL: TLC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
Status: RECRUITING
Conditions: Diabetic Foot Ulcers|Diabetic Wound
Interventions: DRUG: Methylene Blue|OTHER: Milk (control)|DRUG: Methylene Blue and Platelet-Rich Plasma-Fibrin Glue|OTHER: Milk and Platelet-Rich Plasma-Fibrin Glue (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)
Status: TERMINATED
Conditions: Glucose Homeostasis
Interventions: DRUG: Placebo|DRUG: Januvia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Moderate to Severe Ulcerative Colitis
Interventions: DRUG: Induction- PF-06480605 50 mg SC Q4W|DRUG: Induction- PF-06480605 150 mg SC Q4W|DRUG: Induction- PF-06480605 450 mg SC Q4W|OTHER: Induction- Placebo SC Q4W|DRUG: Chronic- PF-06480605 50 mg SC Q4W|DRUG: Chronic- PF-06480605 150 mg SC Q4W|DRUG: Chronic- PF-06480605 450 mg SC Q4W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ancrod (Viprinex™) for the Treatment of Acute, Ischemic Stroke
Status: TERMINATED
Conditions: Stroke|Cerebral Ischemia|Brain Infarction
Interventions: DRUG: Ancrod (Viprinex)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur: An Observational Study Study Protocol: Cardiac Injury and Anaemia Following Surgery for Fractured Neck of Femur
Status: UNKNOWN
Conditions: Anaemia, Myocardial Ischaemia, Fractured Neck of Femur
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modified Atkins Diet Versus Levetiracetam for Refractory Childhood Epilepsy
Status: UNKNOWN
Conditions: Refractory Childhood Epilepsy
Interventions: OTHER: Modified Atkins Diet|DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Collect and Evaluate Data on the Use of IV* Ibuprofen in the Treatment of an Acute Migraine Attack
Status: COMPLETED
Conditions: Episodic Migraine
Interventions: OTHER: saline placebo|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spouse Participation Childbirth Preparation Program on Birth Outcomes
Status: NOT_YET_RECRUITING
Conditions: Fear of Childbirth|Childbirth Self-Efficacy|Mode of Delivery|Childbirth Preparation Program
Interventions: OTHER: Self-efficacy Theory-based Childbirth Preparation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Clear Cell Sarcoma of the Kidney|Recurrent Renal Cell Carcinoma|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: Dalteparin|OTHER: Pharmacological Study|DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metacognitive-Strategy Training in Sub-Acute Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Usual Care Occupational Therapy-Outpatient|BEHAVIORAL: Cognitive Orientation to daily Occupational Performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decoding of the Expression of Tumor Suppressor P2RX7 in Inflammatory and Malignant Colonic Mucosa
Status: TERMINATED
Conditions: Crohn Disease-Associated Colorectal Adenocarcinoma
Interventions: OTHER: Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pranayama and Deep Breathing Exercises Sleep Quality After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic
Interventions: OTHER: pranayama-|OTHER: deep breathing-|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Azacytidine + HAG Regimen vs. Azacytidine for Elderly Patients With Newly Diagnosed Myeloid Malignancy
Status: UNKNOWN
Conditions: Acute Myeloid Leukaemia; Myelodysplastic Syndromes;Chronic Myelomonocytic Leukemia
Interventions: DRUG: Azacytidine, HAG Regimen|DRUG: Azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of High Resolution Colonic Manometry in Studying Motility
Status: WITHDRAWN
Conditions: Gastrointestinal Dysfunction
Interventions: DRUG: Neostigmine|DRUG: Glycopyrrolate|OTHER: Saline (Placebo)|DEVICE: High Resolution Colonic Manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: 0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Morphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Effect of Zingiber Officinale L. Extract in Hypertensive Patients
Status: COMPLETED
Conditions: The Main Focus of This Study is to Evaluate the Safety of Zingiber Officinale L. Tablets as Hypolipidemic Agent in Hypertensive Patients
Interventions: DRUG: Zingiber officinale L. tablets|DRUG: Simvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Anesthesia, Regional
Interventions: DRUG: 0.5% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Trauma Centers RE-AIM at Gun Safety
Status: ENROLLING_BY_INVITATION
Conditions: Firearm Injury|Safety Issues
Interventions: BEHAVIORAL: Adopting Comprehensive Training for FireArm Safety in Trauma centers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety & Efficacy Study of Perifosine + Bortezomib +/- Dexamethasone for Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse
Interventions: DRUG: Perifosine|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Long-Term Safety, Tolerability and Biological Activity of SAR421869 in Patients With Usher Syndrome Type 1B
Status: ACTIVE_NOT_RECRUITING
Conditions: Usher's Syndrome
Interventions: DRUG: Blood draw for the laboratory assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes
Status: COMPLETED
Conditions: Dysglycemia|Obesity
Interventions: DIETARY_SUPPLEMENT: Cinnamon|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of the Drug (SB-656933-AAA) on the Body After a Single Dose in Subjects Who Have Inhaled Ozone
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: SB-656933-AAA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial Using CogWatch for Tea Making Training in Stroke Apraxia and Action Disorganisation Syndrome
Status: COMPLETED
Conditions: Stroke|Apraxias
Interventions: BEHAVIORAL: Task model (CogWatch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An in Situ Study on the Impact of Fluoride Dose and Concentration in Milk on Its Anti-caries Efficacy
Status: COMPLETED
Conditions: Caries
Interventions: DRUG: 1.5 mg Sodium Fluoride in 100 ml milk|DRUG: 1.5 mg sodium fluoride in 200 ml milk|DRUG: 3 mg sodium fluoride in 100 ml milk|DRUG: 3 mg sodium fluoride in 200 ml milk|OTHER: Non-fluoridated milk, 200 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Peptide-based hepatocellular carcinoma vaccine IMA970A|COMBINATION_PRODUCT: Durvalumab|OTHER: Montanide (Adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Purse-string Skin Closure With Negative Pressure Wound Therapy (NPWT) After Ileostomy Reversal
Status: UNKNOWN
Conditions: Surgical Site Infection|Wound Heal
Interventions: PROCEDURE: Linear skin closure with wound drain|PROCEDURE: Purse-string skin closure with negative pressure wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bone-marrow-derived and Placenta-derived Multipotent Mesenchymal Stem / Stromal Cells for Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Placenta-derived MMSCs|BIOLOGICAL: Bone marrow-derived MMSCs|DRUG: Hyalgan 20 mg in 2 ML Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Chronic Administration of Simulect to Subjects Receiving a First Kidney Transplant
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: basiliximab|DRUG: basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
Status: ENROLLING_BY_INVITATION
Conditions: Glaucoma Open-Angle|Glaucoma Eye|Glaucoma; Drugs|Glaucoma, Angle-Closure|Glaucoma Secondary|Glaucoma, Neovascular|Glaucoma Congenital|Surgery|Glaucoma, Pigmentary|Glaucoma Capsulare
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Chronic Pelvic Pain Due to Endometriosis by Transcutaneous Auricular Vagus Nerve Stimulation
Status: RECRUITING
Conditions: Endometriosis
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Plovamer acetate 0.5 milligram (mg)|DRUG: Copaxone 20 mg|DRUG: Plovamer acetate 3 mg|DRUG: Plovamer acetate 10 mg|DRUG: Plovamer acetate 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Regorafenib|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Image-guided Brushing of Pancreatic Cyst Wall in Diagnosis of Cystic Pancreatic Tumors
Status: TERMINATED
Conditions: Pancreatic Tumors
Interventions: PROCEDURE: EUS Guided Fine Needle Aspiration|PROCEDURE: EUS Guided EchoBrush Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers
Status: TERMINATED
Conditions: Exercise-induced Arterial Hypoxemia
Interventions: DRUG: Cetirizine HCl|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tailored Communication to Reduce Cardiovascular Risk
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Artery Disease|Dyslipidemia|Hypertension
Interventions: BEHAVIORAL: Direct-to-patient tailored cardiovascular risk message system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Discontinuation of Magnesium Sulfate After Delivery in Women With Severe Preeclampsia. A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Preeclampsia Severe
Interventions: DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-Prostatectomy
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: Avanafil|DRUG: Avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate the Efficacy and Safety of Telithromycin Given Once Daily Versus Cefuroxime Axetil Given Twice Daily in Children With Middle Ear Infections
Status: TERMINATED
Conditions: Otitis Media
Interventions: DRUG: telithromycin (HMR3647)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
Status: COMPLETED
Conditions: Natural Childbirth|Water Birth|Neonatal Asphyxia|Outcome, Adverse Birth|Labor Pain|Obstetric Pain
Interventions: PROCEDURE: Epidural analgesia|PROCEDURE: Immersion water
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II Study of the Safety and Efficacy of Sernova's Cell PouchTM for Therapeutic Islet Transplantation
Status: TERMINATED
Conditions: Type I Diabetes
Interventions: DEVICE: Sernova Cell Pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare QVM149 and Free Triple Combination of Salmeterol/Fluticasone + Tiotropium
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: QVM149|DRUG: Salmeterol/fluticasone plus tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Multimodal Cognitive Rehabilitation for Traumatic Brain Injury Sustained During Older Adulthood
Status: COMPLETED
Conditions: TBI (Traumatic Brain Injury)|Rehabilitation|Aging
Interventions: BEHAVIORAL: Cognitive Enrichment Program (CEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: AZD3480|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable
Status: COMPLETED
Conditions: Cardiac Output, High|Cardiac Output, Low
Interventions: DEVICE: minimally invasive cardiac output system consisting of arterial line sensor and cardiac output bedside monitor (device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Isolation and Feeling of Loneliness During Critical Illness
Status: COMPLETED
Conditions: Critical Illness|Social Isolation|Anxiety|Depression|Post Intensive Care Unit Syndrome
Interventions: BEHAVIORAL: Social Engagement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Driving Pressure During General Anesthesia for Minimally Invasive Abdominal Surgery (GENERATOR)
Status: RECRUITING
Conditions: Postoperative Complications|Surgery
Interventions: PROCEDURE: Intraoperative ventilation with individualized high PEEP titrated to the lowest ΔP with RMs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Volume of Steroid Hydrodilatation in Treating Patients With Adhesive Capsulitis
Status: RECRUITING
Conditions: Adhesive Capsulitis
Interventions: DRUG: steroid|DRUG: Xylocaine 2 % Injectable Solution|DRUG: Normal saline 2cc|DRUG: normal saline 12cc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Tredaptive on Flow-Mediated Dilation in Cardiac Patients
Status: TERMINATED
Conditions: Coronary Artery Disease|Dyslipidemia
Interventions: DRUG: Tredaptive (1 g extended release niacin+ 20 mg laropiprant)|DRUG: Placebo|DRUG: Tredaptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Plantar Fasciitis With Dorsiflexion Night Splints and Medial Arch Supports
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: dorsiflexion night splint|DEVICE: medial arch support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Levels in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Vitamin D Levels measurement using chemiluminescent assay|DEVICE: Vitamin D level assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Strongest Families Ontario (Formerly the Family Help Program)
Status: COMPLETED
Conditions: Oppositional Defiant Disorder|Behaviour Disorder
Interventions: BEHAVIORAL: Strongest Families Intervention (formerly Family Help)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Administration of Intravenous Morphine in Patients Undergoing Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Postoperative Pain|Morphine|Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Intraoperative morphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p