pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever
Status: WITHDRAWN
Conditions: Liver Failure|Liver Failure, Acute|Drug Induced Liver Injury|Prevention & Control|Fever
Interventions: DRUG: APAP and NAC combination|DRUG: APAP and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation for a Multifunction Ophthalmic Measurement Device
Status: RECRUITING
Conditions: Accommodation Disorder|Keratoconus|Dry Eye|Refractive Errors|Accommodative Fatigue|Accommodative Inertia|Aberration, Corneal Wavefront
Interventions: DEVICE: Measurements of physiological parameters of the anterior chamber|DEVICE: Measurements of the Axial biometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Booster Dose of Ad5-EBOV in Healthy Adults After Primary Immunization
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: 4×10^10vp/1ml Ebola Zaire vaccine (Ad5-EBOV)|BIOLOGICAL: 1.6×10^11vp/2ml Ebola Zaire vaccine (Ad5-EBOV)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Haloperidol for Delirium in Adult Critically Ill Patients
Status: TERMINATED
Conditions: Delirium|Critical Illness|Intensive Care Psychosis|Cognitive Impairment|Cognitive Decline
Interventions: DRUG: Haloperidol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Time-Restricted Eating on Nutritional Status
Status: COMPLETED
Conditions: Energy Expenditure|Anthropometric Measure|Blood Pressure|Biochemical Markers|Healthy Eating Index
Interventions: OTHER: Time-Restricted Eating|OTHER: Energy-Restricted Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens.
Status: COMPLETED
Conditions: Pain, Postoperative|Pulmonary Atelectasis|Mastectomy
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Paravertebral plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Macronutrient Manipulation and Substrate Oxidation During Exercise
Status: COMPLETED
Conditions: Dietary Manipulation
Interventions: OTHER: Diet with a different macronutrient content A|OTHER: Diet with a different macronutrient content B|OTHER: Diet with a different macronutrient content C|OTHER: Interval treadmill running exercise|OTHER: Steady state treadmill running exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Serum Pentraxin 3 and High Sensitive CRP in Female Patients With Gestational Diabetes Mellitus in Second Trimester of Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus in Second Trimester of Pregnancy
Interventions: DIAGNOSTIC_TEST: serum pentraxin 3 and high sensitive CRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Live Birth After Letrozole-stimulated Cycles Versus Hormone Replacement Treatment Cycles for the First Frozen Embryo Transfer in Women With PCOS
Status: RECRUITING
Conditions: PCOS
Interventions: PROCEDURE: Oral Letrozole|PROCEDURE: Oral estradiol valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal Cancer and Their Caregivers
Status: TERMINATED
Conditions: Anxiety Disorder|Colon Cancer|Depression|Fatigue|Rectal Cancer
Interventions: OTHER: educational intervention|PROCEDURE: CAM exercise therapy|OTHER: caregiver-related intervention or procedure|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Stem Cells for Urinary Incontinence: Single Patient Compassionate Use
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Muscle Biopsy|BIOLOGICAL: Injection of autologous stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cetuximab and Bevacizumab in Combination With Paclitaxel and Carboplatin in Stage IIIb/IV NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Cetuximab|BIOLOGICAL: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Preoperative Olfactory Identification Function With Frailty and Postoperative Complications and Mortality
Status: COMPLETED
Conditions: Frailty|Perioperative/Postoperative Complications|Olfactory Disorder
Interventions: DIAGNOSTIC_TEST: Olfactory identification test|DIAGNOSTIC_TEST: Edmonton Frail Scale|DIAGNOSTIC_TEST: Handgrip strength
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Complication|Quality of Life|Surgical Procedure, Unspecified|Lymph Node Metastases|Circulating Tumor Cell
Interventions: PROCEDURE: Open surgery|PROCEDURE: Right colectomy|PROCEDURE: Laparoscopic surgery|PROCEDURE: Central lymphadenectomy and vascular ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SGN-35 (Brentuximab Vedotin) of Patients With Relapsed or Refractory PMLBCL
Status: COMPLETED
Conditions: Primary Mediastinal Large B Cell Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases
Status: RECRUITING
Conditions: NSCLC|EGFR Gene Mutation|EGF-R Positive Non-Small Cell Lung Cancer|Non-small Cell Lung Cancer|Brain Metastases
Interventions: RADIATION: Stereotactic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Aquacel® Ag Versus Mepilex® Border Ag to Manage Bioburden in Leg Ulcers
Status: COMPLETED
Conditions: Leg Ulcers
Interventions: DEVICE: Aquacel® Ag|DEVICE: Mepilex® Border Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection and Enumeration of Circulating Tumor Cells in Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: radiation therapy|DRUG: capecitabine (625mg/m2,bid,d1-5 qw)and oxaliplatin (85mg/m2 d1 qw)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hair Regrowth After Bicoronal Incision
Status: UNKNOWN
Conditions: Alopecia
Interventions: PROCEDURE: Straight Incision|PROCEDURE: Bevelled Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Advertising Availability of Prenatal Ultrasound on Uptake of Antenatal Care in Rural Uganda
Status: COMPLETED
Conditions: Antenatal Care|Maternal Health
Interventions: BEHAVIORAL: Portable obstetric ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: iDAP Injection in the Treatment of Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Allogeneic dopaminergic neural precursor cell(iDAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms|Endometrial Neoplasms|Anus Neoplasms|Rectal Neoplasms|Prostatic Neoplasms
Interventions: DRUG: fluorothymidine F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Assessment of Cannabidiol (CBD) Administrated in Oral Formulations
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: CBD-sesame oil capsule|DRUG: CBD-LNL capsule|DRUG: CBD powder form capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DIETARY_SUPPLEMENT: NUV001 - IR|DIETARY_SUPPLEMENT: NUV001 - GR|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: PK/PD of Single Dose Dapivirine Vaginal Film
Status: COMPLETED
Conditions: Pharmaokinetics
Interventions: DRUG: Dapivirine gel|DRUG: Dapivirine film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Repetitive Transcranial Magnetic Stimulation in Reducing Cocaine Intake in Addicted Patients
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: OTHER: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NEUROBALANCE Training to Improve Postural Control in Individuals with Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury|TBI|Diffuse Axonal Brain Injury|Brain Injuries, Traumatic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy and Acupuncture's Treatment for Chemotherapy-induced Nausea and Vomiting (CINV)
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: OTHER: Acupuncture|OTHER: Auriculotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?
Status: COMPLETED
Conditions: Agitated; State, Acute Reaction to Stress
Interventions: DRUG: Analgesics|DRUG: Antiemetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of the Safety and Efficacy of MK-6096 for Migraine Prophylaxis in Participants With Episodic Migraine (MK-6096-020)
Status: COMPLETED
Conditions: Migraine|Headache
Interventions: DRUG: MK-6096|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Second Line Oxaliplatin Based Chemotherapy Alone Versus Oxaliplatin Based PIPAC and Chemotherapy in Colorectal Peritoneal Carcinomatosis : A Phase II Randomize Mutli-centric Study
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Carcinomatosis
Interventions: PROCEDURE: PIPAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CKDu Treated With Intra-arterial Infusion of Autologous SVF Cells
Status: COMPLETED
Conditions: Chronic Renal Failure of Unknown Cause
Interventions: GENETIC: Adipose-derived stromal vascular fraction cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Probiotic (Bifidobacterium in the Treatment of Infantile Colic (IC)
Status: COMPLETED
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: probiotic (BIfidobacterium, BB-12®)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of an Investigational Drug in Patients With Osteoarthritis (0663-071)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib / Duration of Treatment 12 Weeks|DRUG: Placebo or Ibuprofen / Duration of Treatment 12 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Suture Choice for Improved Scar Outcomes
Status: UNKNOWN
Conditions: Cicatrix
Interventions: PROCEDURE: Intradermal Suture|PROCEDURE: Intradermal Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Pilot Trial of DASH Feeding in Older Low Socioeconomic Adults Without Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure|Heart Failure With Preserved Ejection Fraction
Interventions: OTHER: DASH Diet|OTHER: Usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: hARnessing CAbozantinib and Durvalumab Immuno-oncology Association: ARCADIA Study"
Status: UNKNOWN
Conditions: Bladder Carcinoma
Interventions: DRUG: Cabozantinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration (nAMD)
Interventions: DRUG: OCU-10-C-110 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Changes After Bariatric Surgery
Status: COMPLETED
Conditions: Grade III Obesity|Type 2 Diabetes Mellitus
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|PROCEDURE: Laparoscopic gastric plication|PROCEDURE: Intragastric balloon|DEVICE: Intragastric balloon implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA Gamma 8) Receptor Occupancy of JNJ-64140284 With Newly Developed Transmembrane AMPA Receptor Regulatory Protein (TARP)-Gamma 8 Positron Emission Tomography (PET) [18F]JNJ-64511070 in Healthy Men
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: JNJ-64140284|DRUG: Fluorine-18 Labeled [18F]-JNJ-64511070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibiotic Dosing in Geriatric Patients at the Emergency Department
Status: RECRUITING
Conditions: Elderly Infection|Frailty|Frail Elderly Syndrome|Infection, Bacterial
Interventions: DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Sputum sample|DIAGNOSTIC_TEST: Hemoculture|DIAGNOSTIC_TEST: Urine sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage
Status: UNKNOWN
Conditions: Hordeolum
Interventions: DRUG: neomycin sulfate, polymyxin B sulfate and gramicidin|DRUG: Artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Nutritional Supplement After Lumbar Spine Surgery: A Randomized, Placebo-Controlled, Double-Blind Trial
Status: NOT_YET_RECRUITING
Conditions: Lumbar Spinal Stenosis
Interventions: DIETARY_SUPPLEMENT: Essential amino acids|DIETARY_SUPPLEMENT: Alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II Trial of IMA950 Multi-peptide Vaccine Plus Poly-ICLC in Glioblastoma
Status: COMPLETED
Conditions: CNS Tumor, Adult
Interventions: BIOLOGICAL: IMA 950|BIOLOGICAL: Poly ICLC|OTHER: Immunomonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Repetitive Transcranial Magnetic Stimulation in Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Program of Ultratrace Iobenguane I131 for Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma
Status: APPROVED_FOR_MARKETING
Conditions: Pheochromocytoma|Paraganglioma
Interventions: DRUG: Ultratrace Iobenguane I131
Study Type: EXPANDED_ACCESS
Clinical trial: A Study of C-CAR039 in Subjects With Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: B Cell Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: CD19/CD20-directed Chimeric Antigen Receptor T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing SupportGroove: a Novel Mhealth Intervention for Couples Coping With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Relationship, Marital
Interventions: BEHAVIORAL: SupportGroove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamic Biomarkers to Support Biosimilar Development: Interferon Beta-1A Products
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics|Pharmacodynamics
Interventions: BIOLOGICAL: Interferon beta-1a|BIOLOGICAL: Interferon beta-1a|BIOLOGICAL: Interferon beta-1a|BIOLOGICAL: Peginterferon beta-1a|BIOLOGICAL: Peginterferon beta-1a|BIOLOGICAL: Peginterferon beta-1a|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes
Status: TERMINATED
Conditions: HLA-A2 Positive Cells Present|Metastatic Malignant Neoplasm|Metastatic Malignant Neoplasm in the Brain
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Anti-thyroglobulin mTCR-transduced Autologous Peripheral Blood Lymphocytes|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Trial With Nasonex for Nasal Obstruction Secondary to Adenoids Hypertrophy in Children (P04367)(TERMINATED)
Status: WITHDRAWN
Conditions: Nasal Obstruction|Adenoids Hypertrophy|Adenoidectomy
Interventions: DRUG: mometasone furoate nasal spray|DRUG: placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conquering Hypertension in Vietnam: Solutions at Grassroots Level
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Vietnam National Hypertension Program|OTHER: Expanded community health worker services|BEHAVIORAL: Storytelling intervention|BEHAVIORAL: Home blood pressure self-monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica
Status: UNKNOWN
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: infliximab|DRUG: inactive powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of FOR46 in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: COMPLETED
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse|Multiple Myeloma With Failed Remission
Interventions: DRUG: FOR46
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GreenBladder - Early Detection of Bladder Cancer in Residents in Greenland Using a Urinary Marker and a Mobile Cystoscopy Unit
Status: ENROLLING_BY_INVITATION
Conditions: Urinary Bladder Neoplasms
Interventions: DIAGNOSTIC_TEST: Xpert® Bladder Cancer Detection Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Pirtobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Comprehensive Medication Management Services on Clinical Outcomes in Patients With Cardiovascular Diseases at Primary Care Level
Status: COMPLETED
Conditions: Cardiovascular Diseases in Old Age
Interventions: OTHER: Comprehensive Medication Management services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancer
Status: UNKNOWN
Conditions: Bile Duct Cancer|Pancreatic Cancer
Interventions: DRUG: Cox2 inhibitor (Celecoxib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Olaratumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda
Status: WITHDRAWN
Conditions: Sepsis
Interventions: DRUG: Ascorbic Acid 500Mg/Ml Inj|DRUG: Dextrose in Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of ABT-089 in Adults With Attention Deficit-Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: ABT-089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: HMPL-004 1800 mg/day|DRUG: Placebo|DRUG: HMPL-004 2400 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of IBI302 in Patients With Wet Age-related Macular Degeneration
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: IBI302|DRUG: IBI302|DRUG: IBI302|DRUG: IBI302|DRUG: IBI302|DRUG: IBI302
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women-Focused HIV Prevention in the Western Cape
Status: COMPLETED
Conditions: HIV|Substance Abuse|Violence
Interventions: BEHAVIORAL: Woman-Focused Intervention (Women's Health CoOp)|BEHAVIORAL: Nutrition (Attention-Control)|BEHAVIORAL: VCT Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Respiratory Rate Validation Study - HiCardi+ Wearable Patch Device, Mezoo Co., Ltd.
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive|Idiopathic Pulmonary Fibrosis|Asthma
Interventions: DEVICE: HiCardi+|DEVICE: HiCardi+
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: OTHER: Placebo|RADIATION: 445 nm Diode Laser Wavelength|RADIATION: 660 nm Diode Laser Wavelength|RADIATION: 970 nm Diode Laser Wavelength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
Status: RECRUITING
Conditions: High-grade Glioma|Solid Tumor, Unspecified, Child
Interventions: DRUG: LAM561
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD
Status: ENROLLING_BY_INVITATION
Conditions: Kidney Disease, Chronic|Renal Transplant Failure|Heart Failure|Kidney Failure|Death
Interventions: DRUG: Dapagliflozin 10 mg/day (oral)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: KIDS-STEP_Betamethasone Therapy in Hospitalised Children With CAP
Status: COMPLETED
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Celestamine®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure
Status: COMPLETED
Conditions: COVID-19|Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: Decidual Stromal Cells (DSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Status: RECRUITING
Conditions: Anomalous Coronary Artery Origin|Anomalous Coronary Artery Arising From the Opposite Sinus|Anomalous Coronary Artery Course|Anomalous Coronary Artery With Aortic Origin and Course Between the Great Arteries|Sudden Cardiac Death|Myocardial Ischemia
Interventions: DIAGNOSTIC_TEST: Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ECLIPSE Feasibility Trial (Ensure's Vascular Closure Device Speeds Hemostasis Trial) EU
Status: COMPLETED
Conditions: Angioplasty, Transluminal, Percutaneous Coronary|Coronary Arteriosclerosis
Interventions: DEVICE: 7F Ensure Medical Vascular Closure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy Fat as a Mediator of Vitamin E Adequacy in Individuals With Metabolic Syndrome
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver|Metabolic Syndrome
Interventions: OTHER: Fat-Free Milk|OTHER: Low-Fat Milk|OTHER: Full-Fat Milk|OTHER: Soy Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-Operative Colonization Rates of Femoral Nerve Catheters Treated With Chlorhexidine-Impregnated Patch
Status: COMPLETED
Conditions: Catheter Infections|Spinal Catheter (Epidural) (Subdural); Complications, Infection or Inflammation
Interventions: DEVICE: Chlorhexidine impregnated patch (Biopatch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With Aztreonam
Status: COMPLETED
Conditions: Bacterial Infection
Interventions: DRUG: AZACTAM|DRUG: Ceftazidime-Avibactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: low-carbohydrate diet|BEHAVIORAL: low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise, Muscle Mass, Strength and Body Composition
Status: COMPLETED
Conditions: Sarcopenia|Obesity
Interventions: OTHER: HIT-exercise, low repetition range|OTHER: HIT-exercise, high repetition range|OTHER: HIT-exercise with protein|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-facilitated Treatment for Chronic Pain
Status: RECRUITING
Conditions: Fibromyalgia, Primary
Interventions: DRUG: Psilocybin|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy VS. Nitric-zinc Complex in the Treatment of Plantar Warts.
Status: UNKNOWN
Conditions: Plantar Wart
Interventions: PROCEDURE: Cryoteraphy with liquid nitrogen|PROCEDURE: Nitric-zinc complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Learn About a Monovalent Pneumococcal Conjugate Candidate in Healthy Toddlers
Status: COMPLETED
Conditions: Healthy Participants
Interventions: BIOLOGICAL: mPnC candidate|BIOLOGICAL: mPnC control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot 99mTechnetium-MIBI Single Photon Emission Computed Tomography - Computed Tomography (SPECT-CT) in Papillary Carcinoma (CA) Thyroid
Status: UNKNOWN
Conditions: Papillary Thyroid Cancer
Interventions: RADIATION: 99mTc-MIBI SPECT-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Core Stabilization Exercises and Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DEVICE: Neuromuscular Electrical Stimulation|OTHER: Core Stabilization Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Ixekizumab Using Auto-Injector or Prefilled Syringe in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Ixekizumab Auto-Injector|DRUG: Ixekizumab Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination
Status: COMPLETED
Conditions: Metastatic|Colorectal|Adenocarcinoma
Interventions: DRUG: ZD6474 (vandetanib) 100mg|DRUG: Irinotecan|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: ZD6474 (vandetanib) 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Topical Superoxide Dismutase to Treat Radiation Induced Fibrosis
Status: COMPLETED
Conditions: Radiation Induced Fibrosis to the Head and Neck
Interventions: DRUG: Topical Sodermix Dismutase in the form of Sodermix (SOD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Block of the Supraclavicular Nerves in Clavicular Fractures
Status: COMPLETED
Conditions: Clavicular Fracture|Pain, Acute
Interventions: PROCEDURE: Ultrasound-guided block of the supraclavicular nerves|DRUG: Conventional pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic Fevers
Status: COMPLETED
Conditions: Hereditary Periodic Fevers
Interventions: DRUG: Canakinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Normal Diet and Absolute Diet on Post-polypectomy Patients: an Open-label, Randomized Controlled Trial
Status: UNKNOWN
Conditions: Polyp Colorectal
Interventions: DIETARY_SUPPLEMENT: absolute diet|DIETARY_SUPPLEMENT: normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ISoToxic Accelerated RadioTherapy in Locally Advanced Non-small Cell Lung Cancer: The Phase I/II I-START Trial
Status: COMPLETED
Conditions: Locally Advanced Non-small Cell Lung Cancer
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib With Combination of Gemcitabine, Ifosfamide and Oxaliplatin in Untreated NK/T Cell Lymphoma
Status: TERMINATED
Conditions: Extranodal NK-T-CELL LYMPHOMA
Interventions: DRUG: GIFOX-Bortezomib|DRUG: GIFOX-Bortezomib|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Divalproex Sodium Delayed-Release Tablets, 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DEPAKOTE® Tablets, 500 MG|DRUG: DIVALPROEX SODIUM DELAYED-RELEASE TABLETS, USP, 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Physiopathology
Interventions: BIOLOGICAL: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Regional Anesthesia|Thoracic Surgery|Post-operative Pain|Post-operative Chronic Pain|Pharmacokinetic Analysis|Serratus Anterior Plane Block
Interventions: PROCEDURE: Serratus anterior plane block|DEVICE: patient-controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain Management After Herniorraphy
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
Status: COMPLETED
Conditions: Blepharitis
Interventions: DRUG: TP-03|DRUG: TP-03 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harnessing Placebo Effects: Non-Deceptive Use of Placebo in Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Mouthrinse for Oral Mucositis Study
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: Neem Mouthrinse|DRUG: Placebo Mouthrinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Medifast's 5 & 1 Plan to a Food-based Plan of Equal Calories
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Medifast 5 & 1 Plan for weight loss and weight maintenance|OTHER: Food-based diet plan for weight loss and weight maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staph Household Intervention for Eradication (SHINE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin and Subcutaneous Tissue Bacterial Infections|Staphylococcus Aureus|MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Interventions: DRUG: Chlorhexidine|DRUG: Mupirocin|BEHAVIORAL: Household cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...
Status: RECRUITING
Conditions: B-All|Acute Lymphoblastic Leukemia
Interventions: DIAGNOSTIC_TEST: NGS testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Dexmedetomidine vs Midazolam on Microcirculation in Septic Shock Patients
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DEVICE: Microdialysis Probe (Muscle microdialysis)|DRUG: remifentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Race Difference Moxifloxacin-induced QT Prolongation Between Healthy Chinese and Caucasian Volunteers
Status: UNKNOWN
Conditions: Cardiac Toxicity
Interventions: DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenretinide in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Primary Peritoneal Cavity Cancer
Interventions: DRUG: fenretinide|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laser Therapy on Vaginal Tissue
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Floor Disorders|Vaginal Atrophy
Interventions: OTHER: vaginal laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment.
Status: COMPLETED
Conditions: Cirrhosis|Hepatic Encephalopathy
Interventions: DRUG: l-ornithine l-aspartate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relative Bioavailability of Binimetinib 3 x 15 mg and 45 mg Formulations
Status: UNKNOWN
Conditions: Melanoma|BRAF V600 Mutation|Unresectable Melanoma|Metastatic Melanoma
Interventions: DRUG: Binimetinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities
Status: COMPLETED
Conditions: Dyslipidemia|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Brazil nut flour|DIETARY_SUPPLEMENT: Placebo (cassava flavored flour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal NOTES Hysterectomy Versus Vaginal Hysterectomy
Status: RECRUITING
Conditions: Hysterectomy|Natural Orifice Transluminal Endoscopic Surgery|Vaginal Hysterectomy
Interventions: PROCEDURE: Vaginal NOTES hysterectomy|PROCEDURE: Vaginal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Stenosis
Interventions: DEVICE: Everolimus Eluting Stent|DEVICE: Sirolimus Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combine TACE and RFA Versus TACE Alone for HCC With PVTT
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE|PROCEDURE: RFA|DRUG: pirarubicin,mitomycin and lobaplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia
Status: TERMINATED
Conditions: Ataxia-Telangiectasia (A-T)
Interventions: OTHER: A-T iPS cell line|OTHER: Carrier patients iPS cell line
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Abbreviated, Intensive, Multi-Couple Group Cognitive-Behavioral Conjoint Therapy for PTSD|BEHAVIORAL: Prevention and Relationship Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancies|Bone Marrow Transplant Rejection
Interventions: DEVICE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT