pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rhizarthrosis Study
Status: COMPLETED
Conditions: Rhizarthrosis
Interventions: PROCEDURE: Infiltration with PRP|PROCEDURE: Infiltration with Fat|PROCEDURE: Infiltration with PRP and Fat|PROCEDURE: Infiltration with NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Growth Factor Signature (GFS) as an Intermediate Biomarker of Response for Development of PI3K-Pathway Inhibitors in Patients With Breast Cancer (MK-8669-050)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ridaforolimus + Dalotuzumab|DRUG: Ridaforolimus|DRUG: Dalotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glutamine in Preventing Acute Diarrhea in Patients With Pelvic Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DIETARY_SUPPLEMENT: glutamine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn More About How Acarbose and Metformin Work When Taken Together and How Safe They Are in Indian Patients Who Were Recently Diagnosed With Type 2 Diabetes (T2D)
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: BAY81-9783 (Acarbose/Metformin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Treatment of Irreducible Atlantoaxial Dislocation
Status: RECRUITING
Conditions: Irreducible Atlantoaxial Dislocation
Interventions: PROCEDURE: Anterior and posterior treatment strategy|PROCEDURE: Simple posterior approach treatment strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Loaded Bone Cement in Prevention of Periprosthetic Joint Infections in Primary Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: COMBINATION_PRODUCT: ALBC vs plain bone cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait
Status: COMPLETED
Conditions: Parkinson Disease With Freezing of Gait
Interventions: RADIATION: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Burden of Recreational Water Illness Due to Exposure to Cyanobacteria and Their Toxins in Freshwater Beaches in Canada
Status: ENROLLING_BY_INVITATION
Conditions: Gastroenteritis|Gastrointestinal Diseases|Eye Infections|Skin Infections|Respiratory Tract Infections|Blue Green Algae Poisoning
Interventions: BEHAVIORAL: Cyanobacteria exposure during water contact
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II 5-Azacytidine Plus VPA Plus ATRA
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myelogenous Leukemia
Interventions: DRUG: 5-Azacytidine (5-aza)|DRUG: Valproic Acid|DRUG: All-Trans Retinoic Acid (ATRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
Status: UNKNOWN
Conditions: Coronavirus|Inspiratory Muscle Training|Respiratory Infection|COVID-19
Interventions: DEVICE: Active HD-tDCS|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Epidemiological Study of Subjects With Immune Thrombocytopenic Purpura to Evaluate the Relationship Between Platelet Counts, Endogenous Thrombopoietin Levels, Endogenous Anti-Thrombopoietin Antibodies, and Selected Autoimmune Markers
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic|Immune Thrombocytopenic Purpura
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: adenosine|DRUG: nitroprusside|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chinese Medicine on Patients With Severe Acute Exacerbation of COPD
Status: NOT_YET_RECRUITING
Conditions: Acute Exacerbation Of Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Sanhan Huayin recipe, Qingre Huatan recipe or Zaoshi Huatan recipe|DRUG: Sanhan Huayin recipe placebo, Qingre Huatan recipe placebo or Zaoshi Huatan recipe placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Interaction of ASP015K and Tacrolimus
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP015K and Tacrolimus
Interventions: DRUG: Tacrolimus|DRUG: ASP015K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience
Status: COMPLETED
Conditions: Safety|Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: Kratom|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Symptom-Targeted Approach to Rehabilitation for Concussion
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: PROCEDURE: Manualized cognitive rehabilitation for mild traumatic brain injury (mTBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mixed Exercise and Metabolic Stress in Relationship to Age in Healthy Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hyperglycemia|DRUG: Saline|OTHER: Exercise|PROCEDURE: Blood Draws|OTHER: Fasting procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: sitagliptin (MK0431)|DRUG: Comparator: glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Exposure of BI 409306 in Cerebrospinal Fluid (CSF) Relative to Plasma as Well as to Evaluation of the Effect of Different Doses of BI 409306 on the cGMP (Cyclic Guanosine Monophosphate) Levels in CSF in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 409306|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study
Status: RECRUITING
Conditions: Breast Cancer Female|Cardiometabolic Syndrome|Metabolism Disorder, Lipid|Autonomic Dysfunction|Cardiovascular Diseases in Old Age
Interventions: BEHAVIORAL: HIIT program (8 weeks)|BEHAVIORAL: MPI program (8 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Prevention Program Dedicated to Addictive Behaviors (PREVENTURE) of Vulnerable Teenagers
Status: RECRUITING
Conditions: Addiction, Alcohol|Addiction, Substance
Interventions: OTHER: PREVENTURE Program|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Enteral Nutrition Enriched in Protein and Based on Indirect Calorimetry Measurement in Chronically Critically Ill Patients
Status: UNKNOWN
Conditions: Critically Ill
Interventions: OTHER: Caloric Support (Group 1)|OTHER: Caloric Support (Group 2)|DIETARY_SUPPLEMENT: Protein dose of 1.1 to 1.5 grams per kilogram weight.|DIETARY_SUPPLEMENT: Protein at 1.1 grams per kilogram weight.|DIETARY_SUPPLEMENT: protein at a dose of 1.5 grams per kilogram weight.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vonoprazan Compared to Lansoprazole in Participants With Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Monitoring Exhaled NO in Symptomatic Asthmatic Adults and Children During Anti-inflammatory Treatment
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: The Aerocrine NIOX MINO® Airway Inflammation Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nitrate Formulations and Exercise Performance
Status: RECRUITING
Conditions: Nitrate|Nitrate/Citrulline|Placebo
Interventions: DIETARY_SUPPLEMENT: Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.
Status: COMPLETED
Conditions: Patients With Grade II Ankle Sprain
Interventions: DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Investigate the Effect of Food on the Pharmacokinetics of YM150 Tablet
Status: COMPLETED
Conditions: Healthy Volunteer|Pharmacokinetics of YM150
Interventions: DRUG: YM150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Predictive Diagnostic Criteria for Diagnosis of Transbronchial Biopsies, Echo-guided by Mini-probe in Peripheral Lung Lesions
Status: COMPLETED
Conditions: Transbronchial Biopsies|Peripheral Lung Lesion
Interventions: OTHER: Define predictive criteria for the diagnostic performance of echo-guide samples by mini-probe in peripheral lung lesions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy
Status: COMPLETED
Conditions: Dermatitis|Dermatitis, Atopic|Eczema|Skin Diseases|Skin Diseases, Genetic|Genetic Diseases, Inborn|Skin Diseases, Eczematous|Hypersensitivity|Hypersensitivity, Immediate|Immune System Diseases
Interventions: DRUG: PF-04965842 100 mg|DRUG: PF-04965842 200 mg|DRUG: Dupilumab|DRUG: Oral Placebo|DRUG: Injectable Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Anatomic, Physiologic and Biomechanical Characteristics of the Anal Canal and Pelvic Floor. An Observational Pilot Study
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: OTHER: MRI (magnetic resonance imaging)|OTHER: US (ultra sound)|OTHER: FLIP (functional luminal imaging probe)|OTHER: HRAM (high resolution anal manometry)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyslipidemia
Interventions: DRUG: AZD0780|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radium(223) Dichloride (Alpharadin) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Radium-223 dichloride (BAY88-8223)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mannitol Cream for Post Herpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: Mannitol cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Women With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Pentoxifylline Versus Cilostazol
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DRUG: Pentoxifylline|DRUG: Cilostazol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CATCH-UP Vaccines: Engaged Approaches to Testing in Community/Healthcare Settings for the Underserved (COVID-19)
Status: COMPLETED
Conditions: COVID-19|Vaccine Refusal
Interventions: BEHAVIORAL: Text Message|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Electronic Educational Message with Tailored Questions/Prompts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Pegylated Exenatine Injection (PB-119) in Drug-naïve T2DM Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DRUG: GLP-1 receptor agonist|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Therapy for Hepatocellular Carcinoma >3-<5 cm
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Combined therapy|PROCEDURE: Microwave ablation|PROCEDURE: Transarterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Treatment for Macular Edema Secondary to Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Retinal Vein Occlusion|Treatment|Photocoagulation Burn to Retina|Ranibizumab
Interventions: DRUG: Ranibizumab|DEVICE: laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab + Docetaxel + ADT in mHSPC Patients With DDRD or Inflamed Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Sensitive Prostate Cancer|Prostate Adenocarcinoma|Metastasis Prostate Adenocarcinoma
Interventions: DRUG: Androgen Deprivation Therapy|DRUG: Nivolumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-RAGE in Healthy Subjects and Patients With Inflammatory Lung Disease
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: ARO-RAGE|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Endoscopy and NAFLD
Status: UNKNOWN
Conditions: Obesity|NAFLD|Liver Steatosis|Liver Fibrosis
Interventions: PROCEDURE: bariatric endoscopy, mainly intragastric baloons, plication of stomach too
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect And Safety Of Ziprasidone Compared To Other Atypical Antipsychotic Drug In Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Psychotic Disorders
Interventions: DRUG: ziprasidone versus olanzapine , risperidone or quetiapine|BEHAVIORAL: Panss , CGI-C, UKU-SERS-Pa|PROCEDURE: Blood tests
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804
Status: COMPLETED
Conditions: Osteogenesis Imperfecta, Type I|Osteogenesis Imperfecta Type III|Osteogenesis Imperfecta Type IV
Interventions: DRUG: setrusumab|DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Vitamin D|DRUG: zoledronic acid (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Viral Diagnostics in Adults to Reduce Antimicrobial Consumption and Duration of Hospitalization
Status: COMPLETED
Conditions: Respiratory Virus Infection|Fever of Unknown Origin|Dyspnea|Chest Pain
Interventions: OTHER: Rapid diagnostics using Anyplex TMII RV16 Detection|OTHER: Delayed diagnostics Anyplex TMII RV16 Detection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate the Efficacy and Safety of Octagam 10% in Idiopathic Thrombocytopenic Purpura in Adults
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: DRUG: Octagam 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Refralon®, Concentrate for Solution for Intravenous Injection in Patients With Paroxysmal and Persistent Atrial Fibrillation and Flutter
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Refralon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Type 2 Diabetes and Binge Eating Disorder (BED)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Binge-Eating Disorder
Interventions: BEHAVIORAL: BED treatment|OTHER: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular Hypertension
Status: RECRUITING
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DEVICE: Nanodropper adaptor|DEVICE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Bosentan 125 mg Tablets Immediate Release (IR) Versus Tracleer® 125 mg Tablets IR In Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Bosentan 125 mg|DRUG: Tracleer 125Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peripheral Neuroimmune Mechanisms of Hyperthermia
Status: RECRUITING
Conditions: Hyperthermia|Major Depressive Disorder|Inflammation
Interventions: DEVICE: WBH|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety of MEDI-534 Vaccine Against Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3) in Healthy Children
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MEDI-534|BIOLOGICAL: MEDI-534|BIOLOGICAL: MEDI-534
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL
Status: UNKNOWN
Conditions: Leukemia|Leukemia, Acute|Leukemia, Lymphoblastic|Leukemia, B-cell
Interventions: DRUG: Chidamide|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIB Clinical Trial of Hamsa-1™ in Metastatic Castration Resistant Prostate Cancer (CRPC)
Status: UNKNOWN
Conditions: Metastatic Castration Resistant Prostate Cancer (CRPC)
Interventions: DRUG: Hamsa-1™ TL-118
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Functionality, and the Quality of Life of Patients Who Receive the Freedom Total Knee ® System
Status: COMPLETED
Conditions: Knee Joint Pain
Interventions: DEVICE: Freedom Total Knee|DEVICE: Total Knee Replacement|DEVICE: Freedom Total Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Aprocitentan 25mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: H2 Physical Education: Promoting Cardiometabolic Health by 2 High Intensity Intervallic Training Protocol, Twice a Week at Physical Education
Status: COMPLETED
Conditions: Adolescent Behavior
Interventions: BEHAVIORAL: Intensive high intensity intervallic training group|BEHAVIORAL: Extensive high-intensity intervallic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Osteonecrosis of the Femoral Head by Bone Marrow Transplantation
Status: COMPLETED
Conditions: Necrosis
Interventions: PROCEDURE: core decompression|PROCEDURE: Bone marrow implantation into the necrotic lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Navelbine, Taxol, Herceptin and Neupogen in Stage IV Breast Cancer: A Phase I - II Trial
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Vinorelbine|DRUG: Herceptin|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 135585 XX in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 135585|DRUG: Placebo to BI 135585
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Danshu Capsule and Ursodeoxycholic Acid Capsule in Preventing Recurrence of Choledocholithiasis
Status: COMPLETED
Conditions: Choledocholithiasis|Recurrence
Interventions: DRUG: oral Danshu capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: cyclosporine|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Efficacy and Satisfaction of Ultrasound Therapy Combined With SkinCeuticals A.G.E for Improving Facial Aging
Status: RECRUITING
Conditions: Skin Aging
Interventions: OTHER: SkinCeuticals A.G.E|OTHER: standard cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Solriamfetol for the Treatment of Multiple Sclerosis Fatigue
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis Fatigue
Interventions: DRUG: Solriamfetol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Improvement for Teens With Bariatric Surgery
Status: RECRUITING
Conditions: Obesity, Adolescent|Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Healthy Lifestyle Behavioral Intervention (MBS -supported intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Imaging Study of [18]F-fluoro-3'-Deoxy-3'-L-fluorothymidine ([18]F-FLT) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Who Will be Treated With Gemcitabine or Other Nucleoside Analogs
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: [18]F-FLT PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: FDC of Macitentan and Tadalafil|DRUG: Macitentan|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Japanese Participants With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: BIIB054|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia Refractory|Acute Myeloid Leukemia, in Relapse|Myelodysplastic Syndrome Acute Myeloid Leukemia
Interventions: DRUG: AB8939|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Glaukos® Trabecular Micro-Bypass System, Model iS3, in Subjects With Refractory Glaucoma
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DEVICE: Model iS3 three-stent trabecular micro-bypass system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases
Status: COMPLETED
Conditions: Cervical Cancer|Low-grade Squamous Intraepithelial Lesion,|Human Papillomavirus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobile Application for Cardiovascular Risk Treatment
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Hyperlipidemias|Chronic Disease|Lifestyle Risk Reduction
Interventions: BEHAVIORAL: App-guided lifestyle modification|BEHAVIORAL: A book-based self-education of lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Cettum for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Cettum|PROCEDURE: Traditional indirect moxibustion|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
Status: ACTIVE_NOT_RECRUITING
Conditions: Cataract|Presbyopia|Irregular Astigmatism
Interventions: DEVICE: IC-8 Intraocular Lens (IOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial (RCT) on the Effect of Vitamin D Supplement Prior to Non-surgical Periodontal Therapy: a Feasibility Trial
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Periodontal Diseases|Periodontal Inflammation|Inflammation|Inflammation Gum|Vitamin D
Interventions: DIETARY_SUPPLEMENT: Vitamin D supplementation (30 µg/d)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Intensity-Modulated Pleural Radiation Therapy (IMPRINT) in People With Thymic Cancer That Has Spread to the Lining of the Lungs and Chest
Status: RECRUITING
Conditions: Thymic Malignancies|Pleural Metastases
Interventions: RADIATION: Intensity-Modulated Pleural Radiation Therapy (IMPRINT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Valganciclovir and Placebo for the Prevention of Cytomegalovirus (CMV) After Lung Transplantation
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: valganciclovir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Ranibizumab Therapy With Aflibercept in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Retinal Diseases
Interventions: DRUG: Ranibizumab|DRUG: Aflibercept|DRUG: Ranibizumab and Aflibercept|DRUG: Aflibercept and ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Effect of Chia Seeds on Subjective Appetite and Glycemic Response
Status: COMPLETED
Conditions: Nutrition, Healthy
Interventions: OTHER: 140 calories per 30 gram test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer|Resectable Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: CISPLATIN|DRUG: Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Preferences of Consumers and Clinicians for the Management of Shave Biopsy Sites With a PolyMem Formulation Dressing or Current Standard of Care.
Status: UNKNOWN
Conditions: Healing
Interventions: DEVICE: Shapes by PolyMem dressing|DEVICE: Shapes by PolyMem Silver Dressing|DEVICE: Shapes by PolyMem on one site and Shapes by PolyMem Silver dressing on second site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: Ramelteon|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: MIS+Cathflo Activase (drug)|PROCEDURE: Intraoperative stereotactic CT-Guided Endoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Placebo|DRUG: Aflibercept (ziv-aflibercept, AVE0005, VEGF trap, ZALTRAP®)|DRUG: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)|DRUG: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|Sarcopenia|Sarcopenic Obesity|Obesity|Visceral Obesity|Quality of Life|Surgery|Complication of Treatment|Chemotherapeutic Toxicity|Physical Activity|Oncology
Interventions: PROCEDURE: Esophagectomy or Gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Therapeutic Workplace Initiation Study
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Opioid-Related Disorders|Heroin Dependence|Substance Abuse, Intravenous
Interventions: BEHAVIORAL: Abstinence & Work|BEHAVIORAL: Work Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Vamorolone|DRUG: Prednisone|OTHER: Placebo|DRUG: Vamorolone|DRUG: Prednisone|OTHER: Placebo|DRUG: Vamorolone|DRUG: Vamorolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Treatment for Acute Bacterial Skin Infections (ABSSSI) Caused by Staphylococcus Aureus
Status: COMPLETED
Conditions: Acute Bacterial Skin and Skin-structure Infection(ABSSSI) Due to Staphylococcus Aureus (MSSA)|(Susceptible or Methicillin Resistant)
Interventions: DRUG: Daptomycin|DRUG: PMX-30063-investigational drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Filgotinib in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: filgotinib|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation to Patients Over 65 Years Undergoing THA
Status: COMPLETED
Conditions: Hip Arthroplasty
Interventions: PROCEDURE: interview and advising|BEHAVIORAL: 3 follow up interviews and personal advising|PROCEDURE: interview SF-36 self rated health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Neuropathic Diabetic Ulcer - Foot
Interventions: DEVICE: Integra® Dermal Regeneration Template|OTHER: Conventional Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetic (PK), Pharmcodynamic (PD), and Drug-Drug Interaction of PLX3397 in Patients With Rheumatoid Arthritis Who Are Receiving Methotrexate
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PLX3397
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Patient-Driven Augmented Reality-Based Rehabilitation System to Improve Upper Limb Amputee Outcomes
Status: RECRUITING
Conditions: Amputation|Upper Limb
Interventions: DEVICE: MyoTrain AR|BEHAVIORAL: Motor Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet
Status: WITHDRAWN
Conditions: Comparative Bioavailability
Interventions: DRUG: Metformin 1000 mg granules|DRUG: Metformin 1000 mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Stents Post-dilation With DCB or POBA in Femoropopliteal Arteries
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Orchid 035 DCB Catheter|DEVICE: POBA Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Guided Imagery Practice on Psychosocial Health and Fear of Childbirth in Primiparous Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: BEHAVIORAL: Guided Imagery Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neuroplastic Alterations of the Motor Cortex by Caffeine
Status: COMPLETED
Conditions: Cortical Excitability|Brain Stimulation|Caffeine
Interventions: OTHER: 200 mg caffeine tablet|OTHER: Non-active tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty
Status: RECRUITING
Conditions: Analgesia|Hip Arthropathy|Post Operative Pain
Interventions: PROCEDURE: Intrathecal morphine|PROCEDURE: Pericapsular nerve group block (PENG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat Plus Lenalidomide and Dexamethasone or Lenalidomide Plus Dexamethasone in Multiple Myeloma Patients Who Experience Biochemical Relapse During Lenalidomide Maintenance Therapy
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Vorinostat|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic For the Improvement of Environmental Enteropathy in Pregnant Women in Senegal
Status: RECRUITING
Conditions: Environmental Enteric Dysfunction
Interventions: DRUG: Probiotic|DRUG: Placebo|DEVICE: CapScan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TIV and High Dose TIV in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TIPS Plus Cadonilimab in Advanced HCC With Tumor Thrombosis-associated Portal Hypertension:a Prospective, Single-arm, Phase II Study
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cadonilimab|PROCEDURE: transjugular intrahepatic portosystemic shunt (TIPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery
Status: COMPLETED
Conditions: Wound of Knee|Wound of Hip
Interventions: DEVICE: Single-Use Negative Pressure Wound Therapy|DEVICE: Standard postsurgical dressings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Accelerated Deep TMS in OCD
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Accelerated deep iTBS|DEVICE: Accelerated Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Raltegravir vs. Lopinavir/Ritonavir, Both in Combination With Truvada, in HIV+ Treatment Naive Individuals
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Lopinavir/Ritonavir|DRUG: Truvada
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Salpingectomy for the Prevention of the Ovarian Cancer: Comparison Between Surgical Techniques
Status: COMPLETED
Conditions: Uterine Fibroids|Contraception Desired
Interventions: PROCEDURE: Standard PBS|PROCEDURE: Radical PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: JNJ-40346527 in Treating Participants With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Edicotinib|OTHER: Pharmacokinetic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Limb Loss
Status: COMPLETED
Conditions: Amputation
Interventions: BEHAVIORAL: Supportive-expressive group therapy (SEGT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Randomized, Open-label, Two-way Crossover Study to Assess the Pharmacokinetics and Safety of CK-30 600 mg (Compound K)
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: CK-30|DIETARY_SUPPLEMENT: Red ginseng extracts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Generic Diclofenac Epolamine Acute Pain Due to Minor Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: Diclofenac epolamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Balloon Angioplasty Versus Angioplasty With a Paclitaxel-eluting Balloon for Femoral Artery In-stent Restenosis
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Admiral Xtreme|DEVICE: In.Pact Admiral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section
Status: UNKNOWN
Conditions: Quadratus Lumborum Block|Iliohypogastric/Ilioinguinal Nerve Block|Cesarean Section
Interventions: PROCEDURE: quadratus lumborum block|PROCEDURE: iliohypogastric/ilioinguinal nerve block|PROCEDURE: epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of the Qidni/D Hemodialysis System by Subjects With End-Stage Renal Disease
Status: RECRUITING
Conditions: Kidney Disease, End-Stage
Interventions: DEVICE: Qidni/D Hemodialysis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance of Extensive Hydrolyzed Whey Protein Milk Among Infant With Mild to Moderate CMPA
Status: RECRUITING
Conditions: Mild to Moderate Cows' Milk Protein Allergy
Interventions: OTHER: extensive hydrolyzed protein formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER