pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: General Anesthesia vs. Local Anesthesia in Stereotaxy
Status: UNKNOWN
Conditions: Brain Lesion, Stereotactic Biopsy
Interventions: PROCEDURE: general anesthesia in stereotactic biopsy|PROCEDURE: local anesthesia in stereotactic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Effectiveness of Virtual Reality Self-rehabilitation in the Treatment of Facial Paralysis and Synkinesis
Status: RECRUITING
Conditions: Peripheral Facial Palsy|Rehabilitation|Virtual Reality
Interventions: OTHER: massages|OTHER: motor stimulation and stretching|OTHER: virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mycoprotein and Muscle Protein Synthetic Response
Status: COMPLETED
Conditions: Anabolic Response to Mycoprotein and Micronutrient Ingeston
Interventions: DIETARY_SUPPLEMENT: Mycoprotein ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling
Status: UNKNOWN
Conditions: Necrotic Pulp|Single Root Teeth
Interventions: DRUG: bioceramic sealer|DRUG: MTA|DRUG: resin sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation in Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder
Interventions: DEVICE: Transcranial LED Therapy (Participants ages 9-17)|DEVICE: Transcranial LED Therapy (Participants ages 18-59)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model.
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: outpatient laparoscopic|PROCEDURE: outpatient laparoscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Duloxetine and Placebo in the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: duloxetine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video- Or Direct Laryngoscopy for Endotracheal Intubation in Newborns
Status: COMPLETED
Conditions: Intubation, Intratracheal|Infant, Newborn|Laryngoscopes
Interventions: DEVICE: Videolaryngoscopy|DEVICE: Direct laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the H-Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for Treatment of Major Depressive Episode in the Elderly
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: dTMS treatment (H1 Coil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy
Status: TERMINATED
Conditions: Recurrent Prostate Carcinoma|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: DRUG: Aspirin|OTHER: Laboratory Biomarker Analysis|DRUG: Metformin Hydrochloride|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Parent-administered Reading Therapy Program During Summer Break for Dyslexic Children
Status: COMPLETED
Conditions: Dyslexia
Interventions: OTHER: Parent-administered reading therapy.|OTHER: Dyslexic's Holiday Workbook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CMI-168 on Cognitive Function in Healthy Middle-aged Men and Women
Status: UNKNOWN
Conditions: Cognitive Change
Interventions: DIETARY_SUPPLEMENT: CMI-168|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Relative Bioavailability of Fixed-dose Combination Tablet Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) as a Whole Tablet, as a Split Tablet, and as Crushed Tablet in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir (DRV)|DRUG: Cobicistat (COBI)|DRUG: Emtricitabine (FTC)|DRUG: Tenofovir Alafenamide (TAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DIETARY_SUPPLEMENT: Carnosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura
Status: RECRUITING
Conditions: Henoch-Schönlein Purpura
Interventions: DRUG: Methylprednisolone|DRUG: IVIG|DRUG: other basic supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Advanced or Metastatic Transitional Cell Cancer of the Bladder, Renal Pelvis, or Ureter
Status: COMPLETED
Conditions: Bladder Cancer|Transitional Cell Cancer of the Renal Pelvis and Ureter
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MDX-1411 in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia or Mantle Cell Lymphoma.
Interventions: BIOLOGICAL: MDX-1411
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment With CCTA and MRI in Asymptomatic Patients With Type 2 Diabetes for Detection of Unrecognized Myocardial Scar in Subclinical Coronary Atherosclerosis
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Coronary Atherosclerosis
Interventions: DRUG: iobitridol|DRUG: gadoterate meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's Disorder (TD)
Status: COMPLETED
Conditions: Tourette's Disorder
Interventions: DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib With or Without Rituximab in the Treatment of Waldenstrom Macroglobulinemia or Marginal Zone Lymphoma
Status: TERMINATED
Conditions: Marginal Zone Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Waldenstrom Macroglobulinemia|Refractory Marginal Zone Lymphoma|Refractory Waldenstrom Macroglobulinemia|Waldenstrom Macroglobulinemia
Interventions: DRUG: Carfilzomib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer.
Status: WITHDRAWN
Conditions: Relapsed Hematologic Malignancy|Refractory Hematologic Malignancy
Interventions: DRUG: Tazemetostat|DRUG: Tafasitamab|DRUG: Lenalidomide|DRUG: Acalabrutinib|DRUG: Daratumumab (Intravenously)|DRUG: Mosunetuzumab|DRUG: Daratumumab (Subcutaneously)|DRUG: Hyaluronidase-Fihj|DRUG: Pomalidomide|DRUG: Dexamethasone 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress, Sex, and the Generalization of Fear
Status: COMPLETED
Conditions: Psychological Stress
Interventions: BEHAVIORAL: Stress immediately before learning in males|BEHAVIORAL: Sham control immediately before learning in males|BEHAVIORAL: Stress 30 minutes before learning in males|BEHAVIORAL: Sham control 30 minutes before learning in males|BEHAVIORAL: Stress immediately before learning in females|BEHAVIORAL: Sham control immediately before learning in females|BEHAVIORAL: Stress 30 minutes before learning in females|BEHAVIORAL: Sham control 30 minutes before learning in females
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
Status: RECRUITING
Conditions: Ischemic Stroke|Large-Artery Atherosclerosis (Embolus/Thrombosis)
Interventions: PROCEDURE: carotid artery stenting|PROCEDURE: carotid endarterectomy|DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Anticoagulant|DRUG: Statin|DRUG: PCSK9 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of the Combination of Tandutinib With Temozolomide and Bevacizumab After Radiation and Temozolomide in Patients With Newly Diagnosed With Glioblastoma Multiforme
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Tandutinib, bevacizumab, and temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Jelly and Intracameral Anesthesia Versus Subtenon Anesthesia, in Cataract Surgery
Status: WITHDRAWN
Conditions: Cataract Surgery Anesthesia
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Very Low Carbohydrate Diet on Glycemic, Metabolic, Glycated and Inflammatory Markers in Gestational Diabetes Mellitus
Status: WITHDRAWN
Conditions: Gestational Diabetes|Inflammation|Metabolic Syndrome|Glucose Intolerance During Pregnancy|Glucose Intolerance|Insulin Resistance
Interventions: OTHER: Very low carbohydrate dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Internet-based At-home Physical Training Protocol on Quality of Life, Fatigue, Functional Performance, Aerobic Capacity and Muscle Strength in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: e-training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-61393215 in the Treatment of Depression
Status: COMPLETED
Conditions: Major Depressive Disorder With Anxious Distress
Interventions: DRUG: JNJ-61393215|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 26-week Open Study of telmisartan40mg+amlodipine10mg or telmisartan80mg+amlodipine10 mg in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: fixed-dose combination of telmisartan 40mg+amlodipine 10mg|DRUG: fixed-dose combination of telmisartan 80mg+amlodipine10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Study#1: chlorthalidone (CTD), titrated dose|DRUG: Study #1: spironolactone (SP), titrated dose|DRUG: Study# 2 chlorthalidone (CTD), fixed dose|DRUG: Study# 2 spironolactone (SP), fixed dose|DRUG: Study# 2 irbsesartan (IR), fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Synchronized Nasal Intermittent Positive Pressure Ventilation Using NAVA in Preterm Infants With RDS
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: PROCEDURE: Intermittent nasal positive pressure positive ventilation.|PROCEDURE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sibutramine to Reduce Weight Gain and Improve Smoking Cessation Rates
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Obesity
Interventions: DRUG: Sibutramine|BEHAVIORAL: Behavioral Smoking Cessation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of MR With TENS Conductive Glove in Adults With Neck Myofascial Syndrome.
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Myofascial release with TENS conductive glove|OTHER: Myofascial release without TENS conductive glove|OTHER: Conventional TENS|OTHER: Sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transdermal Administration by a Novel Wireless Iontophoresis Device
Status: RECRUITING
Conditions: Spinal Cord Injuries|Constipation|Fecal Incontinence|Neurogenic Bowel
Interventions: DRUG: Combination of Neostigmine and Glycopyrrolate|DEVICE: I-Box by Dynatronics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-pharmacological Intervention for Patients With Alzheimer's Disease and Family Caregivers (Care Partners Program)
Status: COMPLETED
Conditions: Caregiver
Interventions: BEHAVIORAL: Intervention Condition|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of CM-AT in Children With Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: CM-AT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 30 mg/mL|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Natural Killer T Cells Infusion for the Treatment of Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Glioma|Hepatocellular Cancer|Squamous Cell Lung Cancer|Pancreatic Cancer|Colon Cancer|Prostate Cancer
Interventions: BIOLOGICAL: NKT cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Capecitabine|DRUG: Doxorubicin|DRUG: Ixabepilone|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Brivanib alaninate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamic of AZD1722 in Healthy Male and Female Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD1722|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Ligustrazine in Treating Alcohol Addiction
Status: RECRUITING
Conditions: Alcohol Abuse|Arteriosclerosis
Interventions: DRUG: Ligustrazine by intravenously administration|DRUG: Ligustrazine by mouth|DRUG: Placebo by intravenously administration|DRUG: Placebo by mouth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Peritoneal Glucose Uptake With Use of SGLT2 in Humans Undergoing Peritoneal Dialysis Treatment
Status: UNKNOWN
Conditions: End Stage Renal Disease|Peritoneal Dialysis Complication
Interventions: DRUG: Dapagliflozin 10 MG [Farxiga]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartphone-enabled Health Coaching Intervention for Youth Diagnosed With Major Depressive Disorders
Status: SUSPENDED
Conditions: Disorder, Major Depressive
Interventions: BEHAVIORAL: Smartphone-Assisted MB-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of Pancreatitis
Status: COMPLETED
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Epanova|DRUG: Lovaza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Stage IV Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: nab-paclitaxel|DRUG: FOLFIRINOX|GENETIC: Immunohistochemistry (IHC) Analysis|DRUG: Metformin|DRUG: mFOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beta-lactoglobulin, Immobilisation and Muscle Protein Synthesis
Status: UNKNOWN
Conditions: Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Beta-lactoglobulin|DIETARY_SUPPLEMENT: Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Refractory|Acute Myeloid Leukemia, in Relapse
Interventions: BIOLOGICAL: SC-DARIC33
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK1349572 Drug Interaction With Etravirine and Either Darunavir/Ritonavir or Lopinavir/Ritonavir
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Darunavir|DRUG: Etravirine|DRUG: Ritonavir|DRUG: Lopinavir/ritonavir|DRUG: GSK1349572
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Signaling Mechanisms and Vascular Function in Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: Ruboxistaurin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: National Registry of Rare Kidney Diseases
Status: RECRUITING
Conditions: Adenine Phosphoribosyltransferase Deficiency|AH Amyloidosis|AHL Amyloidosis|AL Amyloidosis|Alport Syndrome|Atypical Hemolytic Uremic Syndrome|Autoimmune Distal Renal Tubular Acidosis|Autosomal Recessive Proximal Renal Tubular Acidosis|Autosomal Recessive Distal Renal Tubular Acidosis|Autosomal Dominant Polycystic Kidney Disease|Autosomal Recessive Polycystic Kidney Disease|Bartter Syndrome|BK Nephropathy|C3 Glomerulopathy With Monoclonal Gammopathy|C3 Glomerulopathy|Calciphylaxis|Crystalglobulinaemia|Crystal-storing Histiocytosis|Cystinosis|Cystinuria|Dense Deposit Disease|Dent Disease|Denys-Drash Syndrome|Dominant Hypophosphataemia With Nephrolithiasis and/or Osteoporosis|Drug Induced Fanconi Syndrome|Drug-Induced Hypomagnesemia|Drug-Induced Nephrogenic Diabetes Insipidus|Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy|Fabry Disease|Familial Hypomagnesemia With Hypercalciuria and Nephrocalcinosis|Familial Primary Hypomagnesemia With Hypocalcuria|Familial Primary Hypomagnesaemia With Normocalciuria|Familial Renal Glucosuria|Fanconi Renotubular Syndrome 1|Fanconi Renotubular Syndrome 2|Fanconi Renotubular Syndrome 3|Fibrillary Glomerulonephritis|Fibromuscular Dysplasia|Focal Segmental Glomerulosclerosis|Generalised Pseudohypoaldosteronism Type 1|Gitelman Syndrome|Heavy-Metal-Induced Fanconi Syndrome|Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes|Hereditary Renal Hypouricemia|Hereditary Hypophosphatemic Rickets With Hypercalciuria|Hyperuricaemic Nephropathy|IgA Nephropathy|Immunotactoid Glomerulonephritis With Organised Microtubular Mononoclonal Immunoglobulin Deposits|Inherited Renal Cancer Syndromes|Intracapillary Monoclonal IgM Without Cryoglobulin|Intraglomerular/Capillary Lymphoma/Leukaemia|Isolated Autosomal Dominant Hypomagnesaemia Glaudemans Type|Liddle Syndrome|Light Chain Cast Nephropathy|Light Chain Proximal Tubulopathy Without Crystals|Light Chain Proximal Tubulopathy With Crystals|Lowe Syndrome|Membranous Nephropathy|Membranoproliferative Glomerulonephritis|Medullary Cystic Kidney Disease|Minimal Change Nephropathy|Mitochondrial Disease Of The Kidney|Monoclonal Immunoglobulin Deposition Disease|Nail Patella Syndrome|Nephrogenic Diabetes Insipidus|Nephrogenic Syndrome of Inappropriate Antidiuresis|Nephronophthisis|Primary Hypomagnesemia With Secondary Hypocalcemia|Primary Hyperoxaluria|Proliferative Glomerulonephritis With Monoclonal IgG Deposits|Proximal Tubulopathy Without Crystals|Pseudohypoaldosteronism Type 1, 2A-2E|Pure Red Cell Aplasia|Retroperitoneal Fibrosis|Sickle Cell Nephropathy|Shiga Toxin Associated Haemolytic Uraemic Syndrome|Steroid Resistant Nephrotic Syndrome|Steroid-Sensitive Nephrotic Syndrome|Thin Basement Membrane Nephropathy|Thrombotic Microangiopathy With Monoclonal Gammopathy|Type 1 Cryoglobulinaemic Glomerulonephritis|Tuberous Sclerosis|Unclassified Monoclonal Gammopathy Of Renal Significance|Vasculitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Taiwan ACE Beads for Embolization Therapy in Symptomatic Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Lower Urinary Tract Symptom|Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: Taiwan ACE Beads
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness Heavy Slow Resistance and Eccentric Training in Rotator Cuff Tendinopathy
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tendinopathy|Subacromial Impingement Syndrome|Bicep Tendinitis
Interventions: OTHER: Heavy slow resistance training|OTHER: Eccentric exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
Status: UNKNOWN
Conditions: Appendicitis
Interventions: PROCEDURE: Polymer clips for closure of the appendiceal stump|PROCEDURE: Endoloops for closure of the appendiceal stump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With TMX-101 in Patients With Carcinoma In Situ (CIS) Bladder Cancer
Status: COMPLETED
Conditions: Carcinoma in Situ|Non Muscle Invasive Bladder Cancer
Interventions: DRUG: TMX-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Radial comparEd to Femoral Approach for CORonary Angiography in Patients With Previous CABG StuDy
Status: COMPLETED
Conditions: Coronary Artery Disease|Vascular Access Complication
Interventions: PROCEDURE: Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Preoperatively Chewing Gum on Sore Throat After General Anaesthesia With a Laryngeal Mask
Status: UNKNOWN
Conditions: Postoperative Sore Throat
Interventions: DRUG: chewed mint gum|OTHER: swallow twice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Study to Evaluate the Efficacy of Treat and Extend Regimen of Aflibercept (EYLEA) as a Second Line Treatment for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema (DME)
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil for IgA Nephropathy
Status: COMPLETED
Conditions: IGA Nephropathy
Interventions: DRUG: mycophenolate mofetil|DRUG: angiotensin blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Flare After b/tsDMARD Discontinuation in Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Discontinuation of biological/targeted synthetic disease modifying anti-rheumatic drug (b/tsDMARD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: 3D1002 in Combination With Oxycodone Hydrochloride Sustained-release Tablets in Patients With Moderate to Severe Cancer Pain
Status: NOT_YET_RECRUITING
Conditions: Cancer Pain
Interventions: DRUG: 3D1002 (50 mg)(Phase IIa)|DRUG: 3D1002 (100 mg)(Phase IIa)|DRUG: 3D1002 (150 mg)(Phase IIa)|DRUG: 3D1002 monotherapy (Phase IIb)|DRUG: OxyContin monotherapy (Phase IIb)|DRUG: 3D1002 + OxyContin (Phase IIb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Alerts in Promoting Bone Densitometry Scans
Status: WITHDRAWN
Conditions: Bone Diseases|Communication
Interventions: BEHAVIORAL: Health Maintenance Topic|BEHAVIORAL: Actionable Sidebar Item|BEHAVIORAL: Best Practice Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Geistlich Fibro-Gide® + CAF in Comparison to CTG + CAF for the Treatment of Recession Defects at 6 Months
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Geistlich Fibro-Gide|PROCEDURE: Connective Tissue Graft (CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Qualitative Study on Patients' (un)Ability and (un)Willingness to Use Telemonitoring in Inflammatory Bowel Diseases
Status: NOT_YET_RECRUITING
Conditions: Telemedicine|Inflammatory Bowel Diseases|Disparity|Health Equity
Interventions: OTHER: Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas
Status: COMPLETED
Conditions: Anaplastic Large-Cell Lymphoma|Non-Hodgkin Lymphoma|T-Cell Lymphoma
Interventions: DRUG: brentuximab vedotin|DRUG: doxorubicin|DRUG: prednisone|DRUG: vincristine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Imaging for the Diagnosis of Small Hepatocellular Carcinoma (< 3 cm)on Cirrhosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: 3 imaging techniques are done
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Nutritional Support on Postoperative Delirium
Status: RECRUITING
Conditions: Postoperative Delirium
Interventions: PROCEDURE: control group|DIETARY_SUPPLEMENT: Nucare Curact group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia
Status: COMPLETED
Conditions: Tobacco Dependence|Schizophrenia
Interventions: DRUG: Hihg-doseNRT, Low-dose NRT, bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: FOLFOXIRI|DRUG: XELOX|OTHER: Chemoradiotherapy|PROCEDURE: TME operation|PROCEDURE: efficacy evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Barcelona School and Schroth for Adolescent Idiopathic Scoliosis.
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis, Thoracic Region
Interventions: OTHER: Barcelona scoliosis physical therapy school|OTHER: International scoliosis schroth therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Topotecan Combined With Anlotinib in Patients With Platinum-resistant Recurrent Ovarian Cancer
Status: WITHDRAWN
Conditions: Platinum-resistant Ovarian Cancer
Interventions: DRUG: Oral Topotecan Combined With Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cell for Aging-related Low-grade Inflammation
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Disease|Aging Problems|Obese|Lipid Metabolism Disorders|Diabetes
Interventions: BIOLOGICAL: umbilical cord mesenchymal stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nifedipine vs Placebo for Maintenance Tocolysis of Preterm Labor.
Status: COMPLETED
Conditions: Obstetric Labor, Premature|Venous Thrombosis
Interventions: DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Evaluation of Sarilumab in Rheumatoid Arthritis Patients (SARIL-RA-EXTEND)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SAR153191 (REGN88)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Co-administration of Bilastine and Montelukast in Patients With SARC and Asthma
Status: COMPLETED
Conditions: Seasonal Allergic Rhinoconjunctivitis|Asthma
Interventions: DRUG: Bilastine 20mg|DRUG: Montelukast 10mg|DRUG: Placebo Bilastine 20mg|DRUG: Placebo Montelukast 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcostal TAP Block With Single or Multiple Injection
Status: RECRUITING
Conditions: Subcostal Transversus Abdominis Plane Block
Interventions: OTHER: Single injection subcostal transversus abdominis plane block|OTHER: Multiple injection subcostal transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehab MATRIX: Impact of a Nursing-Led Acuity Algorithm on Patient Safety and Healthcare Quality
Status: COMPLETED
Conditions: Nurse's Role|Nurse-Patient Relations|Satisfaction|Patient Fall
Interventions: OTHER: Rehab MATRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Magseed Magnetic Marker in Locating Axillary Lymph Nodes in Patients With Breast Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Breast Carcinoma Metastatic in Lymph Node|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIB Breast Cancer AJCC v7
Interventions: PROCEDURE: Axillary Lymph Node Dissection|PROCEDURE: Localization|DEVICE: Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Escalation Trial of Denileukin Diftitox (Ontak) Post Autologous Transplantation
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Denileukin Diftitox (Ontak)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulpotomy Medications in Primary Teeth
Status: RECRUITING
Conditions: Drug Effect
Interventions: PROCEDURE: pulpotomy procedure and Histological evaluation|DIAGNOSTIC_TEST: Immunohistochemistry Protocol for Fibronectin Antibody|DIAGNOSTIC_TEST: Immunohistochemistry Protocol for Osteopontin Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study to Evaluate the Palatability of New Orally Disintegrating Tablets (ODTs) of Praziquantel (PZQ) and L-PZQ Versus Current PZQ Tablets in African Children Age 6-11 Years
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: L-PZQ ODT|DRUG: Rac-PZQ ODT|DRUG: L-PZQ ODT|DRUG: Rac-PZQ ODT|DRUG: Cesol®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparing the Effectiveness of Shotokan-Karate vs. Tai Chi on Balance and Quality of Life in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Shotokan-Karate|OTHER: Tai-Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Contrast Enhanced Spectral Mammography (CESM) Reduce the Number of Benign Biopsies for Calcifications Without Negatively Impacting on Detection/Diagnosis of Clinically Significant Calcifications
Status: UNKNOWN
Conditions: Mammography
Interventions: DIAGNOSTIC_TEST: Contrast enhanced spectral mammography (CESM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects and Safety of Metronidazole in Patients With Gastrectomy
Status: WITHDRAWN
Conditions: Post Gastrectomy State
Interventions: DRUG: metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Chemoradiation Associated With Nimotuzumab as the Treatment of Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Adenocarcinoma
Interventions: DRUG: Nimotuzumab|DRUG: Cisplatin|DRUG: Fluorouracil|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CNS Growth Factors Release and Changes in the Inflammatory Environment in Response to Electrical Stimulation in Subjects With Inflammatory Myelopathies
Status: TERMINATED
Conditions: Inflammatory Myelopathies
Interventions: DEVICE: FES Cycling|DEVICE: Cycling without FES|PROCEDURE: Lumbar puncture|BEHAVIORAL: Mood assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Comparison of Three Methods for Fixation of Hammertoes
Status: WITHDRAWN
Conditions: Acquired Deformities of Toe
Interventions: PROCEDURE: Kirschner wire|PROCEDURE: Integra IPP-On PIP Fusion System|PROCEDURE: Stryker Smart-Toe Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Inclusion of Viral Prescription Pad Resources Increase Responsiveness to Feedback About Antibiotic Prescribing in Primary Care
Status: COMPLETED
Conditions: Infection
Interventions: BEHAVIORAL: Emphasis on the Choosing Wisely Viral Prescription Pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Safety and Tolerability of a New Drug Named Lu AF20513 in Patients With Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Lu AF20513, low dose|DRUG: Lu AF20513, medium dose|DRUG: Lu AF20513, high dose|DRUG: Lu AF20513, double high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of MT-1303
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: MT-1303-Low|DRUG: MT-1303-Middle|DRUG: MT-1303-High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Initiation of Evolocumab on Lipid Profiles Changes in Patients With ACS Undergoing PCI
Status: RECRUITING
Conditions: Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia
Interventions: DRUG: Evolocumab 140 MG/ML|DRUG: Rosuvastatin 5mg|DRUG: Ezetimibe 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure
Status: UNKNOWN
Conditions: COPD|Chest Wall Disease|Neuromuscular Disease|Obesity Hypoventilation
Interventions: OTHER: Pressure support ventilation|OTHER: Pressure control ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of rTMS on Pain Following Stroke.
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Real-rTMS + Gloreha device|DEVICE: Sham-rTMS + Gloreha device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complex Large-bore Radial Percutaneous Coronary Intervention (PCI) Trial
Status: COMPLETED
Conditions: Complex Coronary Lesions
Interventions: PROCEDURE: radial artery access for complex PCI|PROCEDURE: femoral artery access for complex PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Tolerability of Prebiotics on the Microbiota
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: GOS|DIETARY_SUPPLEMENT: GLOS|DIETARY_SUPPLEMENT: FOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients
Status: UNKNOWN
Conditions: Leishmaniasis; American, Cutaneous|Drug Side Effect
Interventions: DRUG: 18-Methoxycoronaridine|DRUG: Glucantime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adavosertib(AZD1775) in Japanese Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Advanced Solid Tumours
Interventions: DRUG: Adavosertib (AZD1775)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of National Cancer Institute Young Adult Stop-Smoking Program
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Cigarette Smoking|Tobacco, Smoking
Interventions: BEHAVIORAL: QuitTXT Study|BEHAVIORAL: Low Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Automatic Deformable Recontouring on the Daily MVCT for Head and Neck Cancer Adaptive Radiotherapy
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: OTHER: Helical intensity-modulated radiotherapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-2)
Status: TERMINATED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: 0.5 mg Conbercept Intravitreal Injection|BIOLOGICAL: 1.0 mg Conbercept Intravitreal Injection|BIOLOGICAL: 2.0 mg Aflibercept Intravitreal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Oral Iron Therapy in Fibromyalgia
Status: COMPLETED
Conditions: Primary Fibromyalgia
Interventions: DRUG: Oral Iron|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy Intervention for Docetaxel-induced Nail Toxicities
Status: COMPLETED
Conditions: Effects of Chemotherapy
Interventions: DEVICE: Frozen gel glove (Elasto-Gel Mitten)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Non-invasive Neuromodulation|DEVICE: Placebo Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is Tunneling Effective in Preventing Failure of Epidural Analgesia? A Randomized Trial
Status: COMPLETED
Conditions: Epidural Catheter|Post Operative Pain
Interventions: PROCEDURE: tunneling epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Naldebain and Video-assisted Thoracoscopic Surgery
Status: RECRUITING
Conditions: Analgesia|Nausea and Vomiting, Postoperative|Itching|Injection Site Reaction|Satisfaction, Patient
Interventions: DRUG: Nalbuphine Sebacate or Sesame oil (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LiPO Teen (the Lifestyle in Pregnancy and Offspring Teenagers
Status: NOT_YET_RECRUITING
Conditions: Obesity|Life Style, Healthy|Follow-up|Gestational Weight Gain|Body Weight
Interventions: BEHAVIORAL: Lifestyle intervention Dietary advise and/or advise on physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Helium-3 MRI Imaging Study in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: He-3 MRI|DRUG: Salbutamol|DRUG: Ipratropium|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC