pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Project STARFISH - PRJ0002679
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|Influenza A|Influenza Type B|RSV Infection
Interventions: DIAGNOSTIC_TEST: The Applied Biosystems™ TaqPath™ COVID-19, Flu A, Flu B, RSV Select Panel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PINGUIN (Postpartum Intervention in Women With Gestational Diabetes Using Insulin)
Status: UNKNOWN
Conditions: Insulin-dependent Gestational Diabetes
Interventions: DRUG: vildagliptin|DRUG: inactive pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RGH-188 (Cariprazine) in Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: cariprazine|DRUG: cariprazine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Diabetic Neuropathy|Complex Regional Pain Syndrome|Carpal Tunnel Syndrome|HIV Neuropathy|Idiopathic Sensory Neuropathy|Peripheral Neuropathy
Interventions: DRUG: Placebo Capsules + Placebo Patch|DRUG: Placebo capsules + Lidoderm®|DRUG: Gabapentin + Placebo|DRUG: Gabapentin + Lidoderm®|DRUG: Gabapentin 300 mg capsules 1800 mg/day + placebo patch|DRUG: Gabapentin 1800 mg/day + Lidoderm patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Medication Reconciliation Protocol in the Primary Care Office-based Setting
Status: COMPLETED
Conditions: Medication Reconciliation Between Patients' Self Report and Electronic Medical Record List
Interventions: OTHER: Printed medication list|OTHER: Open ended question|OTHER: Combined intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accelerated Pre-treatment Evaluation for HCV Infected Persons Who Inject Drugs
Status: COMPLETED
Conditions: Hepatitis C|Intravenous Drug Users
Interventions: DEVICE: Xpert HCV Viral load|DEVICE: Transient elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Helmet vs Face Mask in Patients With Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|Noninvasive Ventilation|Corona Virus Disease|Acute Respiratory Failure
Interventions: DEVICE: Non invasive ventilation via helmet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAMAS: Mentoring Adolescent Mothers at School
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Herpes Simplex Type II|Chlamydia|Gonorrhea|Trichomonas Vaginitis
Interventions: BEHAVIORAL: Mentoring Adolescent Mothers at School (MAMAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Combined Influence of Sepsis and Mechanical Ventilation on the Human Diaphragm
Status: COMPLETED
Conditions: Respiration, Artificial
Interventions: PROCEDURE: surgery|PROCEDURE: multi-organ sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC
Status: UNKNOWN
Conditions: Melanoma (Skin)|Squamous Cell Carcinoma of the Skin|Carcinoma, Squamous Cell of Head and Neck|Carcinoma, Adenoid Cystic
Interventions: BIOLOGICAL: CV8102|BIOLOGICAL: CV8102 + anti-PD-1 therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Biliary Tract Cancer
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Radiation Pneumonitis After Three-dimensional Conformal Radiation Therapy (3D-CRT) in Patients With Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: RADIATION: Free breathing|RADIATION: Breath holding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke
Status: RECRUITING
Conditions: Dyslipidemias|Stroke, Acute Ischemic
Interventions: DRUG: combination of high-dose rosuvastatin and ezetimibe|DRUG: high-dose rosuvastatin single administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia
Status: COMPLETED
Conditions: Hypoxic-ischemic Encephalopathy
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cannabis Based Medicine Extracts and Placebo in Patients With Pain Due to Spinal Cord Injury
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: GW-1000-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolomics of Roux-en-Y Gastric Bypass (RYGB) With Gastrostomy
Status: COMPLETED
Conditions: Type II Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Gastric Band|PROCEDURE: Gastric Sleeve|PROCEDURE: Gastrostomy Tube
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remimazolam Total Intravenous Anesthesia Under Analgesia Nociception Index-guidance
Status: COMPLETED
Conditions: Knee Osteoarthritis|Total Knee Arthroplasty|Remimazolam
Interventions: DRUG: remimazolam group|DRUG: propofol group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Bronchopulmonary Dysplasia by Instillation PS and Mononuclaer Cells in Preterms
Status: UNKNOWN
Conditions: Neonates Premature|Ventilator Support
Interventions: BIOLOGICAL: CBMNC|BIOLOGICAL: PS+CBMNC|BIOLOGICAL: PS|OTHER: Placeo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AML2003 - Standard-Therapy vs Intensified Therapy for Adult Acute Myeloid Leukemia Patients <= 60 Years
Status: COMPLETED
Conditions: Leukemia, Nonlymphocytic, Acute
Interventions: DRUG: Cytarabine vs. Cytarabine+Amsacrine+Mitoxantrone|PROCEDURE: early allogeneic PBSCT within induction therapy|PROCEDURE: autologous PBSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study of Povetacicept (ALPN-303) in Autoimmune Kidney Diseases
Status: RECRUITING
Conditions: Lupus Nephritis|Immunoglobulin A Nephropathy|Membranous Nephropathy|Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: DRUG: povetacicept|DRUG: povetacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Fluzone® Quadrivalent Vaccine Administered to Healthy Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, No Preservative|BIOLOGICAL: Fluzone Quadrivalent vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Physical Therapy in Stem Cell Transplant Recipients for Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis|Osteo Arthritis Knee|OA Knee
Interventions: OTHER: Forward Walking|OTHER: Physiotherapy Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
Status: COMPLETED
Conditions: Other Acute Postoperative Pain
Interventions: DRUG: Paracetamol|DRUG: Dipyrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma
Status: SUSPENDED
Conditions: Glioblastoma Multiforme
Interventions: BIOLOGICAL: ICT-107|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis Infection
Status: COMPLETED
Conditions: Blastomycosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Mobile Phone Short Message Service (SMS) Reminders to Enhance Appointment Attendance in DM Patients
Status: UNKNOWN
Conditions: Appointments and Schedules|Diabetes Mellitus, Type 2
Interventions: OTHER: Mobile phone text message reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Micronutrient Supplement Effects on Cognitive Outcomes in Post-Acute TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DIETARY_SUPPLEMENT: Swisse Womens 50+ Ultivite Multivitamin|DIETARY_SUPPLEMENT: Holland and Barrett Triple Strength Omega-3 Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Regular Human Insulin|DRUG: Insulin glargine|DRUG: Supplemental insulin (Insulin lispro)|DRUG: Supplemental insulin (Insulin aspart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Viral Suppression Among Transgender Women Living With HIV in Santo Domingo
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Gender Affirming Abriendo Puertas (Opening Doors) (GAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Miswak Chewing Sticks on Periodontal Pathogens and Its Impact on the Progression of Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Miswak chewing sticks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti Xa Levels Under Two Different Regimens of Enoxaparin VTE Prophylaxis After Sleeve Gastrectomy for Morbid Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: 40mg Enoxaparin|DRUG: 60mg Enoxaparin|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER-2/Neu Vaccine Plus GM-CSF in Treating Patients With Stage III or Stage IV Breast, Ovarian, or Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: HER-2/neu peptide vaccine|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir
Status: RECRUITING
Conditions: HIV|Obesity|Obesity, Infant|Maternal Obesity During Childbirth|Maternal Obesity Complicating Pregnancy
Interventions: DEVICE: Dolutegravir-based antiretroviral therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep vs Moderate Neuromuscular Blockade With Rocuronium in Patients Undergoing Endolaryngeal Procedures
Status: COMPLETED
Conditions: Laryngoscopic Surgical Procedures
Interventions: PROCEDURE: Deep Neuromuscular Blockade|PROCEDURE: Moderate Neuromuscular Blockade|DRUG: Sugammadex|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beta2-adrenergic Agonism and Muscle Remodelling
Status: UNKNOWN
Conditions: Hypertrophy|Physiologic Hypertrophy|Physical Activity
Interventions: DRUG: Formoterol|DRUG: Terbutaline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Alcohol Use Disorders
Interventions: DRUG: doxazosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SEAL™IT: Saccular Endovascular Aneurysm Lattice System Interventional Pivotal Trial
Status: NOT_YET_RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: The SEAL™ Saccular Endovascular Aneurysm Lattice System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexlansoprazole in Healing and Maintaining Healing of Erosive Esophagitis
Status: TERMINATED
Conditions: Erosive Esophagitis
Interventions: DRUG: Dexlansoprazole|DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T Cell Therapy for Desensitization in Kidney Transplantation
Status: RECRUITING
Conditions: Kidney Transplant|Kidney Failure|End Stage Renal Failure on Dialysis
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: CART-BCMA|BIOLOGICAL: huCART19|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Safe Transplants for Systemic Sclerosis
Status: TERMINATED
Conditions: Systemic Sclerosis|Scleroderma
Interventions: DRUG: Rituximab|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: rATG|DRUG: Methylprednisolone|DRUG: G-CSF|BIOLOGICAL: IVIg|BIOLOGICAL: Autologous Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygenation Test During General Anesthesia
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: CPAP and 100% oxygen|PROCEDURE: CPAP and 31% oxygen|PROCEDURE: No CPAP and 100% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparum
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: artesunate & mefloquine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression
Status: COMPLETED
Conditions: Contraception|Postpartum Depression|Lactation
Interventions: DRUG: Depot medroxyprogesterone acetate|DRUG: Depot medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Status: UNKNOWN
Conditions: Genitourinary Syndrome of Menopause (GSM)|Vaginal Dryness|Burning|Pain|Dyspareunia|Dysuria
Interventions: DEVICE: Fractionated Laser (Pixel CO2-Alma)|DEVICE: Fractionated Laser (Pixel CO.2-Alma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management
Status: NOT_YET_RECRUITING
Conditions: Interstitial Cystitis|Chronic Pain|Pelvic Floor; Relaxation|Pelvic Floor Disorders
Interventions: DEVICE: High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device|DRUG: Botulinum Neurotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning In Abdominal Organ Transplantation
Status: COMPLETED
Conditions: Kidney Disease|Liver Disease|Pancreas Disease
Interventions: PROCEDURE: RIPC by Inflation of Pneumatic Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Determine the Effects of BXT-51072 in Diabetic Patients Undergoing Angioplasty (PCI)
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Type 2 Diabetes
Interventions: DRUG: BXT-51072
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery
Status: COMPLETED
Conditions: Pediatric Central Nervous System Tumor
Interventions: DRUG: tozuleristide|DEVICE: Canvas System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Prophylactic Treatment for Hand-Foot Syndrome in Patients Treated With Oral Xeloda (Capecitabine).
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Corticosteroids|DRUG: Placebo|DRUG: capecitabine [Xeloda]|DRUG: dexpantenol [Bepantol]
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Increasing Doses of DaxibotulinumtoxinA for Injection (DAXI for Injection) in the Treatment of Moderate or Severe Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines
Interventions: BIOLOGICAL: DaxibotulinumtoxinA for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Structured Lifestyle Program in Primary Care. Changes in Lifestyle Habits and Cardiovascular Risk.
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Lifestyle Risk Reduction|Primary Care
Interventions: BEHAVIORAL: structured lifestyle program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Zinc Supplement in Regorafenib Treated mCRC Patient
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Regorafenib|DIETARY_SUPPLEMENT: Zinc gluconate supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - TNFi vs Abatacept
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tumor Necrosis Factor Inhibitors|DRUG: Abatacept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Induction immunochemotherapy followed by Adebrelimab plus concurrent chemoradiotherapy|DRUG: Induction immunochemotherapy followed by concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulinastatin Improves and Prevents Cardiac Dysfunction Induced by Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Pharmacological Action
Interventions: DRUG: Ulinastatin|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Compare the Pharmacokinetic Characteristics and Food Effect of Pelubiprofen (30mg) Tablet IR and Pelubiprofen SR (as a Pelubiprofen 45 mg) Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Males
Interventions: DRUG: Pelubiprofen IR (Pelubiprofen 30mg) TID|DRUG: Pelubiprofen SR (Pelubiprofen 45 mg) BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of a Butyrate Enema on the Systemic Concentration of Short Chain Fatty Acids
Status: COMPLETED
Conditions: SCFA Metabolism
Interventions: DIETARY_SUPPLEMENT: Sodium butyrate|DIETARY_SUPPLEMENT: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: "Efficacy of Hybrid Systems ("Topping Off") Versus Rigid Spinal Fusion in Lumbar Fusion Surgery: A Dual-center, Prospective, Randomized Pilot Study ("CD Horizon BalanC")"
Status: UNKNOWN
Conditions: Spine Surgery
Interventions: DEVICE: Solera™ Medtronic|DEVICE: CD HORIZON BalanC™ Medtronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH
Status: RECRUITING
Conditions: Langerhans Cell Histiocytosis|LCH
Interventions: DRUG: FCN-159
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Training for CFS Following EBV Infection in Adolescents
Status: COMPLETED
Conditions: Fatigue Syndrome, Chronic|Epstein-Barr Virus Infection
Interventions: BEHAVIORAL: Mental training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of an Electronic Pain Management Programme (ePain) for Working Population With Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: OTHER: ePain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erector Spinae Plane Block for Uncomplicated Renal Colic
Status: RECRUITING
Conditions: Renal Colic|Kidney Stone
Interventions: PROCEDURE: Erector Spinae Plane Block (ESPB)|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Non-Hodgkins Lymphoma|Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: XmAb13676
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locked-in Syndrome Caused by Pulmonary Arteriovenous Malformation: A Case Report
Status: UNKNOWN
Conditions: Locked-In Syndrome；Pulmonary Arteriovenous Malformation
Interventions: OTHER: In this study, only cases were collected and reported without any intervention or adverse reactions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regenerative Ability of TAMP BG and BD in Pulpotomized Primary Teeth
Status: TERMINATED
Conditions: Pulpotomy
Interventions: DRUG: TAMP bioglass|DRUG: Biodentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Polyclonal anti-T-cell antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: MBX-8025 2 mg Capsule|DRUG: MBX-8025 5 mg Capsule|DRUG: MBX-8025 10 mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants With Recent Onset Chronic Cough (MK-7264-043)
Status: COMPLETED
Conditions: Chronic Cough
Interventions: DRUG: Gefapixant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed-dose Combination of Oxycodone [OXIcodona] + IbuproFEN in Pain Relief After Third Molar Extraction
Status: RECRUITING
Conditions: Pain
Interventions: DRUG: FDC of oxycodone 5 mg/ibuprofen 400 mg|DRUG: Tylex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Major Depressive Disorder
Interventions: DRUG: Adderall-XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tailoring a Lifestyle Intervention to Address Obesity Disparities Among Men
Status: COMPLETED
Conditions: Weight Loss|Obesity
Interventions: BEHAVIORAL: Tailor Made: Solutions for your health (A su Medida: Soluciones para su salud)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of Immediate Post-operative Intravesical Epirubicin in Intermediate&High Risk Non Muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Carcinoma of Urinary Bladder, Superficial
Interventions: DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of HPV Vaccination on Prevention of Cervical HPV Infection in Sikkim, India
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: The study being observational in nature, there is no intervention. The investigators will only collect cervical samples from married women within a specified age range at different intervals.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Autogenous Demineralized Dentin as a Bone Graft Substitute in Management of Periodontal Intrabony Defects
Status: UNKNOWN
Conditions: Intrabony Defect
Interventions: PROCEDURE: autogenous demineralized dentin graft as bone substitute in treatment of intrabony defect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of RH5.1/Matrix-M in Adults and Infants Living in Tanzania
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: RH5.1/Matrix-M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: DHA-PPQ|DRUG: PQ (0.75)|DRUG: PQ (0.4)|DRUG: PQ (0.2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Comparison of Continuously Monitored Vital Signs in Pediatric Patients With Cancer.
Status: COMPLETED
Conditions: Pediatric Cancer|Febrile Neutropenia|Oncology|Chemotherapy-induced Neutropenia
Interventions: DEVICE: Everion®|DEVICE: CORE®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Economic Evaluation of Treatment Modalities for Position Dependent Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Positional Obstructive Sleep Apnea
Interventions: DEVICE: Sleep position trainer|DEVICE: Mandibular advancement device|DEVICE: Continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: ACP Specialist Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness|Sarcopenia|Muscle Wasting
Interventions: DEVICE: Ultrasound Philips CX50|OTHER: Frailty Index Questionnaire|OTHER: Muscle strength tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps.
Status: UNKNOWN
Conditions: Montelukast|Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Montelukast|DRUG: Prednisolone|DRUG: Fluticasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Estradiol (E2) Levels in Breast Cancer Patients During Endocrine Therapy by High Performance Liquid Chromatography-tandem Mass Spectrometry (LC-MS /MS)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: AIs|DRUG: OFS+AIs|DRUG: FUL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alefacept in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma or Peripheral T-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Alefacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increase of Prostaglandin E2 in Reversal of Ductal Constriction After Dietary Restriction of Polyphenols
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: OTHER: restrict polyphenol-rich foods
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities in Ukraine
Status: COMPLETED
Conditions: Depression|PostTraumatic Stress Disorder
Interventions: BEHAVIORAL: CETA (Common Elements Treatment Approach)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver
Status: COMPLETED
Conditions: Metastatic Carcinoma in the Liver|MLH1 Gene Mutation|MSH6 Gene Mutation|PMS2 Gene Mutation|Stage IV Colorectal Cancer|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Improved Formula on Fatty Acids and Mineral Metabolism in Infants
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: β-Palmitate Content|OTHER: Placebo|OTHER: β-Palmitate Content Naturely in Human Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and/or Lung
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: cetuximab|BIOLOGICAL: filgrastim|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Early Urinary Disorders After Stress Incontinence Surgery: The Role of Vaginal Wall Tension.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Traditional Burch colposuspension|PROCEDURE: Modified Burch colposuspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renohemodynamic Effects of Combined empagliflOzin and LosARtan
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetic Kidney Disease
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Losartan 50Mg Tab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML>60a
Status: COMPLETED
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: Cytarabine|BIOLOGICAL: human stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection
Status: COMPLETED
Conditions: AIDS Dementia Complex|HIV Infections
Interventions: DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
Status: RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DRUG: BI 764524|DRUG: Sham comparator to BI 764524|DRUG: Aflibercept (Eylea®) - US only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Campaign Effects on General Hospital Admissions and Mortality Among Children
Status: COMPLETED
Conditions: Measles Vaccination|Oral Polio Vaccine|Non-specific/Heterologous Effects of Vaccines|Mortality|Morbidity|Children
Interventions: BIOLOGICAL: Measles vaccine|BIOLOGICAL: Oral polio vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Influence of Frailty on Cardiovascular Events and Mortality in Patients With COPD.
Status: RECRUITING
Conditions: Role of Frailty in COPD
Interventions: OTHER: Assessment of cardiovascular events, cardiovascular mortality, all-cause mortality, and mortality due to COPD at 12 and 24 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Bioequivalence Study of Levetiracetam Versus Keppra
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Levetiracetam (Lotus Pharmaceutical Co.,Ltd.)|DRUG: Keppra (Levetiracetam - USB SA Pharma Sector)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Vitamin D Supplementation and Clinical Improvement in COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 10000 IU|DIETARY_SUPPLEMENT: Vitamin D3 1000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Incidence of Postpartum Hepatitis in Pregnant Women With Chronic Hepatitis B Virus Infection
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Block and Erector Spinae Block in Postoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: PROCEDURE: Serratus anterior block (SAB)|PROCEDURE: Erector spinae block|DRUG: Saline (as a placebo)|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open Positron Emission Tomography Study to Assess the Effects of Varying Mass of AZD4694 on Radioligand Binding Parameters in Healthy Volunteers and Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Maximum Diagnostic Mass of [18Fluor]AZD4694
Interventions: OTHER: [18Fluor]AZD4694|OTHER: [18Fluor]AZD4694|OTHER: [18Fluor]AZD4694
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Driving Performance Among Trained and Untrained Drivers Using a Driving Simulator
Status: COMPLETED
Conditions: Prevention Harmful Effects|Accidents, Traffic|Accident Prevention
Interventions: BEHAVIORAL: Risk Anticipation -Perception Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Positive Psychological Intervention on Resilience Improvement in Nurses
Status: NOT_YET_RECRUITING
Conditions: Nurses|Resilience, Psychological|Positive Psychology
Interventions: BEHAVIORAL: Positive Psychology Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Association Between Postural Balance and Muscle Activity of the Lumbar and Lower Limb Muscles in Female With or Without Adolescent Idiopathic Scoliosis (AIS) During Standing Balance Tasks With Upper Limb Movement
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DIAGNOSTIC_TEST: Proprioceptive-stabilometric assessment machine (ProKin 252, TecnoBody®, Italy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of TF2 Carcinoembryonic Antigen (CEA) Antibody in Patients With Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: TF2/IMP288
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-751 in Patients With Recurrent Breast Cancer After Taxane (Taxol or Taxotere) Therapy.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: ABT-751
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Efficacy of Sleepgift Blanket on Sleep Quality and Heart Health
Status: RECRUITING
Conditions: Sleep
Interventions: DEVICE: Active sleepgift blanket|DEVICE: Sham Sleepgift Blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Proof-of-Concept Study of the Safety and Efficacy of Alfimeprase to Rapidly Open Arteries and Restore Brain Function Following a Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: alfimeprase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Assessment of Abdominal Massage on Feeding Tolerance of Preterms
Status: RECRUITING
Conditions: Preterm Birth Complication|Digestive System Disease
Interventions: OTHER: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Of Ruxolitinib (INCB018424) With Preoperative Chemotherapy For Triple Negative Inflammatory Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Breast Cancer (IBC)
Interventions: DRUG: Ruxolitinib|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Physiotherapy Sessions Focussing on Arm Rehabilitation for People After Stroke During the Early Inpatient Period? A Feasibility Study
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Upper limb physiotherapy programme|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Effects on Fear Extinction in Social Phobia
Status: NOT_YET_RECRUITING
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Fear extinction|DRUG: Cannabidiol Cap/Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures
Status: COMPLETED
Conditions: Femoral Fracture|Cognition Disorders|Cortisol; Hypersecretion
Interventions: DRUG: 8 mg of dexamethasone|DRUG: 12,5 mg of 0,5 % of levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Human Papilloma Virus Genotypes and Treatment Outcomes of Intralesional Immunotherapy of Anogenital Warts
Status: RECRUITING
Conditions: Human Papilloma Virus|Anogenital Wart
Interventions: BIOLOGICAL: the Quadrivalent Vaccine (Gardasil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Long-term Safety and Efficacy of SerpinPC in Subjects With Hemophilia Who Completed a Sponsored SerpinPC Clinical Trial
Status: RECRUITING
Conditions: Hemophilia A|Hemophilia B|Hemophilia A With Inhibitor|Hemophilia B With Inhibitor
Interventions: DRUG: SerpinPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of SPECT-CT for Comparison of Dosimetry Methods in PSMA-targeted Radioligand Therapy (SPECTacular Study)
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DIAGNOSTIC_TEST: SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.
Status: RECRUITING
Conditions: Viral Infection
Interventions: BIOLOGICAL: HLA-matched VSTs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subjective Efficacy of Ramelteon on Sleep in Adults With Chronic Insomnia.
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Based Mindfulness Intervention
Status: COMPLETED
Conditions: Parental Stress|Parent and Child Stress|Parental and Child Obesity|Child Obesity
Interventions: BEHAVIORAL: Lifestyle counseling|BEHAVIORAL: Parenting Mindfully for Health (PMH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION