pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pelvipower for Faecal Incontinence
Status: RECRUITING
Conditions: Faecal Incontinence
Interventions: DIAGNOSTIC_TEST: High Resolution Anorectal Manometry|DIAGNOSTIC_TEST: Endoanal Ultrasound|OTHER: Bowel diary|OTHER: MYMOP2|OTHER: FIQOL|OTHER: FISI|OTHER: Follow up call|OTHER: St Mark's incontinence score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: carvedilol|DRUG: placebo|DRUG: carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide Receptor Radionuclide Therapy Administered to Participants With Meningioma With 67Cu-SARTATE™
Status: COMPLETED
Conditions: Meningioma
Interventions: DRUG: Cu-64 SARTATE and Cu-67 SARTATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Colloid Versus Crystalloid in Post-operative Pediatric Cardiac Patients for Fluid Resuscitation
Status: COMPLETED
Conditions: Cardiac Diseases
Interventions: OTHER: 5% albumin|OTHER: crystalloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Single-dose Low-volume PEG Plus Bisacodyl vs. Split-dose PEG for Bowel Preparation in Morning Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation
Interventions: DRUG: Polyethylene glycol and bisacodyl|DRUG: Split-dose polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Effect of Seltorexant Compared to Placebo on Respiration During Sleep in Adult Participants With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Seltorexant 40 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Increased Early Pain Relief by Adding Vertebroplasty to SBRT
Status: RECRUITING
Conditions: Spine Metastases|Radiation Therapy|Pain
Interventions: PROCEDURE: Vertebroplasty|PROCEDURE: Stereotactic Body Radiation Therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Effect of Extreme Dietary Carbohydrate Restriction on Hepatic Glucose Production
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Calorie and Carbohydrate Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: AliveCor|BEHAVIORAL: Behavioral Altering Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Robot and tDCS Based Proprioceptive Rehabilitation After Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: 1x1 anodal tDCS|DEVICE: Sham tDCS|BEHAVIORAL: Robotic Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Responses to Two Dose Varivax +/- MMR-II
Status: TERMINATED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: MMR-II|BIOLOGICAL: Pro-Quad|BIOLOGICAL: Varivax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma With EZH2 Gene Mutation
Status: COMPLETED
Conditions: Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Insertion Ultrasound for Lateral-Position Spinal in Cesarean Delivery
Status: UNKNOWN
Conditions: Cesarean Section|Spinal Anesthesia|Lumbar Ultrasound
Interventions: DEVICE: Accuro SpineNav3D|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Apixaban for Treatment of Embolic Stroke of Undetermined Source
Status: COMPLETED
Conditions: Embolic Stroke of Undetermined Source
Interventions: DRUG: Apixaban|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Blood Glucose Levels During Infusion With HepaGam B (HBIG) in Post-liver Transplant Patients
Status: COMPLETED
Conditions: Hepatitis B
Interventions: PROCEDURE: glucose monitoring before and after HepaGam B administration|BIOLOGICAL: HepaGam B (Hepatitis B Immune Globulin (HBIG))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of EU103 in Advanced or Metastatic Solid Tumors That Have Failed Standard Therapy
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: EU103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Is The First Study Using Escalating Doses Of PF-03758309, An Oral Compound, In Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: PF-03758309
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Can Ultrasound Guided Biopsy be Used as an Alternative to Hysteroscopy?
Status: UNKNOWN
Conditions: Endometrial Cancer|Endometrial Neoplasms|Endometrial Hyperplasia|Endometrial Polyp
Interventions: DIAGNOSTIC_TEST: Ultrasound guided biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia
Status: COMPLETED
Conditions: Cachexia; Cancer|Weight Loss|Lung Cancer|Gastrointestinal Cancer
Interventions: DRUG: Remune|OTHER: EXCAP©®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Peer Delivery of HIV Self Test to Improve Linkage to HIV Prevention
Status: UNKNOWN
Conditions: HIV
Interventions: OTHER: Incentivised network delivery of HIV-ST|OTHER: Peer navigator delivery of HIV-ST|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Safety Study of Recombinant Human Acid Sphingomyelinase in Acid Sphingomyelinase Deficiency Patients
Status: COMPLETED
Conditions: Human Acid Sphingomyelinase Deficiency
Interventions: DRUG: Recombinant human acid sphingomyelinase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hybrid Systems in Comparison to the Rigid Spondylodesis in Lumbar-spine Fusion
Status: TERMINATED
Conditions: Spondylolisthesis
Interventions: DEVICE: Experimental: hybrid system|DEVICE: Active Comparator: Plif
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Stretching Increases Spine and Thoracic Mobility
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Diaphragm stretching.|OTHER: Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly Patients
Status: COMPLETED
Conditions: Anesthesia, Spinal|Dexmedetomidine|Bradycardia
Interventions: DRUG: normal saline|DRUG: atropine 0.5mg|DRUG: ephedrine 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Performance of DKL Crosslinked Sodium Hyaluronate 26 Dermal Filler for Cheek Augmentation
Status: COMPLETED
Conditions: Aging Problems
Interventions: DEVICE: DKL crosslinked sodium hyaluronate 26|DEVICE: Juvéderm Voluma™ with lidocaine (Allergan, Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)
Status: COMPLETED
Conditions: Facial Wrinkles at the Nasolabial Folds
Interventions: DEVICE: Dermal Gel Extra (DGE)|DEVICE: Restylane|DRUG: EMLA Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: Alisporivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Application of 68Ga-PSMA PET/MR for Diagnosis and Staging in Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Malignant Neoplasm
Interventions: DRUG: 68Ga-PSMA|DEVICE: PET/MR|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PERIODONTAL HEALTH IN PATIENTS ACUTELY ADMITTED FOR MYOCARDIAL INFARCTION: A CASE CONTROL STUDY
Status: UNKNOWN
Conditions: Myocardial Infarction, Acute|Periodontitis
Interventions: OTHER: Full-mouth periodontal examination using computerised Florida probe
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of ACP on Surgical Repair of Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Autologous conditioned plasma|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-cholecystectomy Major Bile Duct Injury
Status: COMPLETED
Conditions: Common Bile Duct Injury
Interventions: PROCEDURE: Early BDI reconstruction without abdominal sepsis control|PROCEDURE: Early BDI reconstruction with abdominal sepsis control|PROCEDURE: Delayed reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vulvar Lichen Sclerosus Treatment Using Adipose Tissue Associated With Autologous Platelet-rich Plasma.
Status: COMPLETED
Conditions: Vulvar Lichen Sclerosus
Interventions: DRUG: Injection of autologous fatty tissue associated with autologous platelet-rich plasma.|DRUG: Corticosteroids (clobetasol 0.05%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Dovitinib in First-line Metastatic or Locally Advanced Non-resectable Adrenocortical Carcinoma
Status: COMPLETED
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat BCG Vaccinations for the Treatment of Established Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type One|Diabetes Mellitus, Type I|Autoimmune Diabetes|Covid19
Interventions: BIOLOGICAL: Bacillus Calmette-Guérin|BIOLOGICAL: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peer and Text Message Support to Reduce Readmission Rates for Patients Discharged From Acute Psychiatric Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychiatric Illness
Interventions: OTHER: Text4Support|OTHER: Peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryoablation Combined With Camrelizumab and Apatinib in Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab; Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: PROCEDURE: Autologous mini punch grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resistance Training on Substrate Metabolism During the Menstrual Cycle
Status: TERMINATED
Conditions: Menstrual Cycle|Substrate Metabolism
Interventions: BEHAVIORAL: EFP|BEHAVIORAL: LFP|BEHAVIORAL: ELP|BEHAVIORAL: LLP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Intervention to Improve Post-TKR Support and Function
Status: COMPLETED
Conditions: Osteoarthritis|Arthroplasty, Replacement, Knee
Interventions: BEHAVIORAL: Patient support sessions|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.
Status: TERMINATED
Conditions: Aortic Valve Disorder
Interventions: DRUG: SAVR Warfarin|DRUG: SAVR Aspirin|DRUG: TAVR Warfarin and clopidogrel|DRUG: TAVR Aspirin and clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis Eczema|Atopic Dermatitis|Eczema
Interventions: OTHER: Team-Based Connected Health (TCH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
Status: RECRUITING
Conditions: Cancer|Liver Cirrhosis|Chronic Hepatitis|Hepatitis B|Hepatitis C|Diabetes|COPD
Interventions: DIAGNOSTIC_TEST: Multi-analyte Blood Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ONCOFID-P-B in the Intravescical Therapy of Patients With Non-muscle Invasive Cancer of the Bladder.
Status: COMPLETED
Conditions: Non-Invasive Papillary Carcinoma of Bladder
Interventions: DRUG: Oncofid-P-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agitation and Aggressivity in Alzheimer's Disease Patients: A Cohort Study
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: NeuroPsychiatric Inventory Clinician (NPI-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: REMOTION: a Trial to Investigate the Feasibility and Potential Effectiveness of a Blended, Transdiagnostic Intervention for Symptom Reduction and Improvement of Emotion Regulation in an Outpatient Psychotherapeutic Setting
Status: COMPLETED
Conditions: Mental Disorders
Interventions: BEHAVIORAL: REMOTION|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial
Status: RECRUITING
Conditions: Insomnia|Dementia|Frontotemporal Dementia
Interventions: DRUG: Lemborexant 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SLC022 in Treating Pain Associated With Post Herpetic Neuralgia
Status: UNKNOWN
Conditions: Postherpetic Neuralgia
Interventions: DRUG: SLC022|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Home-based Treadmill Training and Walking Attainment in Young Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: home-based treadmill training|DEVICE: Treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Dexmedetomidine and Long-term Outcomes in Elderly After Major Surgery
Status: COMPLETED
Conditions: Overall Survival
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia
Status: RECRUITING
Conditions: Post-Extraction Socket Hemostasis|Post-Extraction Socket Pain Relief|Post-Extraction Socket Healing
Interventions: BIOLOGICAL: A-PRF|COMBINATION_PRODUCT: Bone-wax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HAIC Plus Sorafenib Versus TACE Plus Sorafenibfor Advanced HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|PROCEDURE: Transarterial chemoembolization|DRUG: TACE regimen|DRUG: HAIC Regimen|DRUG: Oral Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening Effort, Cognition and Anxiety-depression in Listening Satisfaction by Hearing Aid Users
Status: NOT_YET_RECRUITING
Conditions: Listening Effort|Cognitive Function 1, Social|Anxiety|Depression|Satisfaction, Consumer|Amplification|Hearing Aid
Interventions: DIAGNOSTIC_TEST: The Spatial Hearing Questionnaire, MINI-MENTAL STATE EXAMINATION, International Outcome Inventory - Hearing Aid, Glasgow Hearing Aid Benefit Profile, BECK-II and STAI questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anemia Studies in CKD: Erythropoiesis Via a Novel PHI Daprodustat - Pediatric (ASCEND-P)
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaemia
Interventions: DRUG: Daprodustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diclofenac Potassium vs Nimesulide in the Treatment of Fever and Pain in Children With Upper Respiratory Tract Infection
Status: WITHDRAWN
Conditions: Upper Respiratory Tract Infections
Interventions: DRUG: diclofenac potassium|DRUG: nimesulide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Derived Mononuclear Cells in Treating Diabetic Patients With Critical Limb Ischemia
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Diabetic Foot
Interventions: PROCEDURE: Autologous Bone Marrow Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketone Ester Supplementation on Neuro-cardiovascular Responses to Stress in Humans
Status: COMPLETED
Conditions: Ketosis
Interventions: DIETARY_SUPPLEMENT: D-beta-hydroxybutyrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial
Status: COMPLETED
Conditions: Uveitis|Macular Edema
Interventions: DRUG: Dexamethasone intravitreal implant 0.7 mg|DRUG: Intravitreal Methotrexate 400 µg|DRUG: Intravitreal Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity & Pregnancy: Factors Influencing Participation in a Physical Activity and Nutritional Counseling Program
Status: TERMINATED
Conditions: Obesity|Overweight|Pregnancy
Interventions: BEHAVIORAL: physical activity and nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Expression Analysis of the COPB 2 and Bcl-2 in Early Stages of Endometrial Carcinoma
Status: COMPLETED
Conditions: Endometrial Carcinoma Cellular Diagnosis
Interventions: PROCEDURE: 1.hysterectomy with bilateral oophorectomy and pelvic lymphonodectomy. 2 explorative curettage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis
Status: RECRUITING
Conditions: Endocarditis|Stroke
Interventions: OTHER: Neurological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Histidine Oral Supplementation as a Therapeutic Modality for Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: l-Histidine|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Checkpoint Inhibitor Plus Erlotinib or Crizotinib for EGFR or ALK Mutated Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Ipilimumab|DRUG: Erlotinib|DRUG: Crizotinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Microbiome and Polymorphic Light Eruption
Status: UNKNOWN
Conditions: Polymorphic Light Eruption
Interventions: OTHER: Octeniderm (octenidine dihydrochloride, 1-propanol, 2- propanol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of the Validation of General Evaluation Score (GES) in the Prediction of Hepatocellular Carcinoma Risk Among Patients With Advanced Fibrosis and Cirrhosis Who Achieved Sustained Virological Response for Hepatitis C Virus After Direct Acting Antiviral Drugs
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: General Evaluation Score (GES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Safety and Drug Levels of CCI15106 Inhalation Powder in Healthy Adults and Adults With Moderate Chronic Obstructive Pulmonary Disease. Study of CCI15106 Levels in People Standing Near the Person Inhaling the Drug
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: CCI15106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Estramustine, and Thalidomide in Treating Patients With Prostate Cancer Previously Treated With Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: estramustine phosphate sodium|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the VitaBreath on Exercise Tolerance in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: VitaBreath|OTHER: Pursed Lip Breathing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cooperation for Primary Care Patients on Sick Leave for CMD: Care Manager and Workplace Intervention - CO-WORK-CARE
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Workplace convergence dialogue|BEHAVIORAL: Care Manager
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Stress Reduction (MBSR) Program Combined With Endurance Exercise Training: a Help in Treatment for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Endurance exercise training|OTHER: Mindfulness-based-stress-reduction|OTHER: Both interventions together|OTHER: Vo2max measurements|GENETIC: Telomerase activity on a blood sample|OTHER: Quality of life (questionnaires)|OTHER: Cerebral IRMf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of FOLFIRI-AD in Patients With Metastatic Colorectal Cancer UGT1A Genotype 1
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan high doses|DRUG: Irinotecan standard doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Buprenorphine Treatment for Neonatal Abstinence Syndrome - Pilot Study
Status: UNKNOWN
Conditions: Drug; Withdrawal Symptoms, Neonatal|Withdrawal|Fetus and Newborn Affected by Other Maternal Medication
Interventions: DRUG: BZDs + opiate exposure treated with BPN|DRUG: Opiates exposure treated with BPN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Fatigue Etiology in Intensive Care Unit Survivors: the Role of Neuromuscular Function
Status: WITHDRAWN
Conditions: Chronic Fatigue Syndrome|Intensive Care Unit|Muscle
Interventions: OTHER: Questionnaires|BIOLOGICAL: blood test|OTHER: Maximal effort test|DEVICE: actigraphy|DEVICE: Neuromuscular evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I, Open-label Study to Assess the Safety and Efficacy of Poly-ICLC Plus Nivolumab in Unresectable Hepatocellular Carcinoma Patients
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Different Macronutrients on Gastrointestinal Hormone Secretion After Gastric Bypass Operation
Status: UNKNOWN
Conditions: Bariatric Surgery (Gastric Bypass)|Overweight
Interventions: OTHER: Mealtest: High protein 200 kcal 200 ml liquid meal consumed during 10 minutes|OTHER: Mealtest: High fat 200 kcal 200 ml liquid meal consumed during 10 minutes|OTHER: Mealtest: High carbohydrate 200 kcal 200 ml liquid meal consumed during 10 minutes|OTHER: Mealtest: High fat 200 kcal 200 ml liquid meal with pancreatic lipase inhibitor consumed during 10 minutes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection and Biopsy Guidance of Nasopharyngeal Carcinoma Based on Artificial Intelligence and Endoscopic Images
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Image-Guided Biopsy
Interventions: DIAGNOSTIC_TEST: Nasopharyngeal Endoscopy image-guided Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PINPOINT: Gaming Technology for SCD Pain
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia in Children|Sickle Cell Thalassemia|Sickle Cell SC Disease
Interventions: OTHER: Pinpoint app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Yoga for Improving the Well-being of Desk-based Workers
Status: RECRUITING
Conditions: Perceived Stress|Depression|Anxiety|Mindfulness|Self-Compassion|Compassion|Work Engagement|Productivity|Heart Rate Variability|Mental Wellbeing|Musculoskeletal Pain
Interventions: OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Functional Training Versus Resistance Exercises in Patients With Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: OTHER: Resistence Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: CR845 0.5 mcg/kg|DRUG: CR845 1 mcg/kg|DRUG: CR845 1.5mcg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Serratus Block and the Emergence of Post-thoracotomy Pain Syndrome
Status: COMPLETED
Conditions: Thoracic Neuritis
Interventions: PROCEDURE: Serratus anterior plane catheter block|PROCEDURE: Patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided TAP Block Versus Caudal Block in Pediatrics
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Transversus Abdominis Plane Block|PROCEDURE: Caudal Block|DRUG: Bupivacaine 0.25% Injectable Solution|DEVICE: Ultra-sound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy for Locally Advanced Esophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Carcinoma
Interventions: DRUG: mFOLFOX6|COMBINATION_PRODUCT: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anonymous Treatment on the Internet for Alcohol Dependence: A Randomised, Controlled Trial
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Dependence|Harmful Alcohol Use|Alcohol Use Disorder
Interventions: BEHAVIORAL: Alkoholhjälpen counselor support|BEHAVIORAL: eChange Alkoholhjälpen|BEHAVIORAL: Alkoholhjälpen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Ferrous Sulfate to Intravenous Ferumoxytol in Antepartum Iron Deficiency Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Related|Anemia, Iron Deficiency
Interventions: DRUG: Ferumoxytol Injection [Feraheme]|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exposure, Relaxation, & Rescripting Therapy-Child
Status: COMPLETED
Conditions: Post Trauma Nightmares|Traumatic Stress
Interventions: BEHAVIORAL: Exposure, Relaxation, & Rescripting Therapy-Child
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Community-based Network for Drug Abusers
Status: UNKNOWN
Conditions: Adolescent
Interventions: BEHAVIORAL: A video competition|BEHAVIORAL: A training workshop|BEHAVIORAL: A mass promotional campaign
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Observational Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Not applicable (no therapy is administered as part of this study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Impact on the Evolution of the Disease in the Medium Term of the Implementation of a System of Extended Follow-up by Telephone Interview of Patients With an Eating Disorder Organized by the Nurses of the Eating Disorder Referral Center
Status: RECRUITING
Conditions: Eating Disorders|Recurrence|Relapse
Interventions: OTHER: semi-standardized interview|OTHER: care experience questionary
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mitroflow DL Post Approval Study- North America
Status: TERMINATED
Conditions: Aortic Stenosis|Aortic Regurgitation|Aortic Valve Insufficiency|Heart Valve Diseases|Cardiovascular Abnormalities|Cardiovascular Diseases|Congenital Abnormalities|Heart Diseases|Pathological Conditions, Anatomical
Interventions: DEVICE: Mitroflow DL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smart Technology for Anorexia Nervosa Recovery
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Smart-Treatment for Anorexia Nervosa Recovery (STAR)|BEHAVIORAL: Present-focused Anorexia Nervosa Coping Treatment (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors|Triple Negative Breast Cancer|Ovarian Cancer|Gastric Cancer|Colorectal Cancer|Glioblastoma|Biliary Tract Cancers|Pancreatic Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.
Status: RECRUITING
Conditions: Obesity
Interventions: OTHER: Saline + saline|OTHER: Neurotensin + saline|OTHER: GLP-1 + saline|OTHER: GLP-1 + Neurotensin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasounds Evaluation of Asymptomatic Perimandibular Muscles Treated With Dry Needling
Status: COMPLETED
Conditions: Asymptomatic State|Temporomandibular Joint|Masticatory Muscles
Interventions: DEVICE: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial of CXD101 in Combination With Nivolumab in Patients With Metastatic Microsatellite-Stable Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Neoplasms Malignant
Interventions: DRUG: CXD101 in Combination With Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IPTp-DP Versus IPTp-SP in Malawi
Status: COMPLETED
Conditions: Malaria|Pregnancy
Interventions: DRUG: Sulfadoxine-pyrimethamine|DRUG: dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapy of Complicated Intra-Abdominal Infections With Moxifloxacin or Ertapenem
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)|DRUG: Ertapenem intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Sterilized Clean vs Sterilized Aseptic Dental Implant Surgery
Status: UNKNOWN
Conditions: Endosseous Dental Implant Failure|Bone Loss
Interventions: PROCEDURE: Single Dental Implants|PROCEDURE: Sterilized Aseptic|PROCEDURE: Sterilized Clean|PROCEDURE: Full-Mouth Dental Implants|PROCEDURE: Partial Rehabilitation|PROCEDURE: Duration of Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b/2 Study of Liposomal Annamycin (L-Annamycin) in Subjects With Previously Treated Soft-Tissue Sarcomas (STS) With Pulmonary Metastases
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Pulmonary Metastasis
Interventions: DRUG: Liposomal Annamycin (L-Annamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Anesthesia, Spinal|Arthroplasty, Replacement, Knee|Pain Management|Early Ambulation|Ambulatory Surgical Procedures
Interventions: DRUG: Mepivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Epoetin Beta Treatment in Anemic Participants With Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Online Informational and Peer Support App for Patients With Low Anterior Resection Syndrome
Status: UNKNOWN
Conditions: Patient Empowerment|Low Anterior Resection Syndrome|Colo-rectal Cancer|Peer Group|Patient Satisfaction|Health Attitude|Health Knowledge, Attitudes, Practice
Interventions: OTHER: Interactive online informational and peer support app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction in Silico of Pathological Response in a Prospective Cohort Study of Early Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Biopsy|PROCEDURE: Blood samples|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Lung Injury, Acute|Respiratory Distress Syndrome, Adult|Bronchiolitis Obliterans
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KN046 in Subjects With Advanced Pancreatic Ductal Adenocarcinoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: KN046|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia
Status: COMPLETED
Conditions: Sickle Cell Anemia|Sickle Cell Thalassemia|Iron Overload|MRI
Interventions: OTHER: Cardiac and Liver T2* MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interstitial Fluid Pressure (IFP) Pilot Study in Melanoma Patients
Status: WITHDRAWN
Conditions: Advanced Cancers|Melanoma
Interventions: PROCEDURE: Tumor Interstitial Fluid Pressure (IFP) assessments|DEVICE: Transducer-catheter SPC-320 + Amplifier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Explore the Role of Gut Flora in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Parkinsons Disease With Dementia|Parkinson-Dementia Syndrome|Parkinson Disease 2|Parkinson Disease 3|Parkinson Disease 4
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irreversible Electroporation (IRE) Followed by Nivolumab in Patients With Metastatic Pancreatic Cancer.
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Sham stimulation|PROCEDURE: Vagus stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Idiotype Vaccine for Low-Grade Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, Low-Grade
Interventions: BIOLOGICAL: FavId (Id-KLH) active immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of VC-02™ Combination Product in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: COMBINATION_PRODUCT: VC-02 Combination Product (aka PEC-Direct)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach to Infantile Spasms
Status: SUSPENDED
Conditions: Infantile Spasm
Interventions: DRUG: Cosyntropin Injectable Suspension, 1 mg/mL|DRUG: Cosyntropin Injectable Suspension 1 MG/ML + vigabatrin|DRUG: Vigabatrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Localization of Peripheral Pulmonary Lesions: A Pilot Study
Status: WITHDRAWN
Conditions: Peripheral Lung Lesions
Interventions: PROCEDURE: Conventional bronchoscopy|DEVICE: VIDA Pulmonary Workstation 2|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Lu AF35700 After Repeated Dosing in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lu AF35700|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Study is Done in Healthy Japanese Volunteers. It Looks at How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: BI 705564|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective, Observational Study to Collect Clinical Safety and Performance Data of POLYMAILLE® EXTRA THIN Vascular Prothesis
Status: COMPLETED
Conditions: Aneurysm Abdominal|Peripheral Aneurysms|Arterial Disease Occlusive|Prothesis
Interventions: DEVICE: Vascular surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of CHF6333 in Healthy Subjects
Status: COMPLETED
Conditions: Non-Cystic Fibrosis Bronchiectasis|Cystic Fibrosis
Interventions: DRUG: CHF6333 (Part 1 - SAD)|DRUG: Placebo (Part 1 - SAD)|DRUG: CHF6333 (Part 2 - MAD)|DRUG: Placebo (Part 2 - MAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bacteria on Mood and Bowel Symptoms in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|IBS
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Articaine Computer-controlled and Conventional Delivery for Anterior and Middle Superior Alveolar Nerve Block for Tooth Extraction
Status: WITHDRAWN
Conditions: Local Anesthesia
Interventions: DRUG: Computer controlled 4% articaine delivery by Anaeject|DRUG: Conventional 4% articaine delivery by carpule syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT