pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Weight Loss in Patients With COVID-19 and Influenza in Comorbidity With NCDs: a Pilot Prospective Clinical Trial
Status: COMPLETED
Conditions: Clinical Trial
Interventions: DIETARY_SUPPLEMENT: "Analimentary detoxication" (ANADETO) weight loss based on very-low-calorie-diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function
Status: COMPLETED
Conditions: Heart Failure|Asymptomatic Systolic Dysfunction
Interventions: DRUG: Nesiritide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Clinical Trial to Evaluate the Effects of Acupuncture in Patients on Prolonged Mechanical Ventilation
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Calcium-cholecalciferol Foodstuffs and Calcium-cholecalciferol Supplement
Status: COMPLETED
Conditions: Vitamin D Status|Healthy
Interventions: DIETARY_SUPPLEMENT: fortified milk|DIETARY_SUPPLEMENT: plain milk|DIETARY_SUPPLEMENT: fortified orange juice|DIETARY_SUPPLEMENT: plain orange juice|DIETARY_SUPPLEMENT: calcium-vitamin D supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Proof of Mechanism Study With GSK2126458 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GSK2126458|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Ovarian Neoplasms|Prostatic Neoplasms|Lung Neoplasms|Gastrointestinal Neoplasms
Interventions: DRUG: Motexafin Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TOMUS-Trial Of Mid-Urethral Slings
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: retropubic mid-urethral sling (TVT)|PROCEDURE: transobturator mid-urethral sling (TVT-O and the Monarc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Doses Of An Experimental Glucocorticoid Compound To Prednisone And Placebo In Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PF-04171327|DRUG: PF-04171327|DRUG: PF-04171327|DRUG: PF-04171327|DRUG: prednisone|OTHER: prednisone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wonders & Worries: A Clinical Trial of a Psychosocial Intervention for Children Who Have a Parent With Cancer
Status: COMPLETED
Conditions: Cancer|Psychological Adjustment
Interventions: BEHAVIORAL: Wonders & Worries Psychosocial Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: BIOLOGICAL: TNFa Antagonist - Infliximab|BIOLOGICAL: TNFa Antagonist - Adalimumab|BIOLOGICAL: Anti-IL12/23 or anti-IL23 - Ustekinumab|BIOLOGICAL: Anti-IL12/23 or anti-IL23 - Risankizumab|BIOLOGICAL: Anti-integrin - Vedolizumab IV|BIOLOGICAL: Anti-integrin - Vedolizumab IV and SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Quadrivalent Influenza Vaccine in Children Aged 3-8 Years Old
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Two doses of quadrivalent influenza vaccine|BIOLOGICAL: One dose of quadrivalent influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain|Pain|Arthritis|Musculoskeletal Pain|Osteoarthritis
Interventions: OTHER: Therapist treated massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RISE - Study of the AGN1 LOEP SV Kit in Patients With Vertebral Compression Fractures
Status: RECRUITING
Conditions: Vertebral Compression Fracture|Vertebral Compression|Vertebral Fracture
Interventions: DEVICE: AGN1 LOEP SV Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of CNI-based Regimen Versus CNI-free Regimen in Kidney Transplant Recipients.
Status: TERMINATED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus|DRUG: Cyclosporin A (CsA)|DRUG: Tacrolimus|DRUG: Enteric Coated - Mycophenolate Sodium (EC-MPS)|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PRedictOrs, PHEnotypes and Timing of Obstructive Sleep Apnea in Acute Coronary Syndrome
Status: UNKNOWN
Conditions: ST Elevated Myocardial Infarction|Sleep-Disordered Breathing|Sleep|NSTEMI - Non-ST Segment Elevation MI
Interventions: DIAGNOSTIC_TEST: Polygraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Minimising the Adverse Physiological Effects of Transportation on the Premature Infant
Status: UNKNOWN
Conditions: Prematurity|Transfer Injury|Brain Injuries|Intraventricular Hemorrhage|Vibration; Exposure|Noise Exposure
Interventions: BEHAVIORAL: Physiological changes to noise and vibration exposure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization With or Without Mixing the Chemotherapy With Lipiodol for Unresectable HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: OTHER: Embolization|OTHER: Infusion of anticancer agent|OTHER: Infusion of mixture of anticancer agent and lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin vs Colchicine in Decrease of Troponin I of High Sensitivity in Patients With Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Cardiovascular Diseases|Arthritis, Rheumatoid
Interventions: DRUG: Atorvastatin|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Melatonin and Vitamin C on COVID-19
Status: COMPLETED
Conditions: Covid19|SARS-CoV Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: melatonin|DIETARY_SUPPLEMENT: Placebo|OTHER: Symptom Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: QFR-based diagnostic strategy|DIAGNOSTIC_TEST: FFR-based diagnostic strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear
Status: RECRUITING
Conditions: Acetabular Labrum Tear|Femoro Acetabular Impingement|Chondral Defect|Bone Marrow Aspirate Concentrate|Mesenchymal Stromal Cell
Interventions: BIOLOGICAL: BMAC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma of the Cervix, Stage IVB
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Cisplatin/Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptive (OC) Progestin Dose and Breast Proliferation
Status: COMPLETED
Conditions: Oral Contraceptive
Interventions: DRUG: Oral Contraceptive: Ortho-Novum® 1/35|DRUG: Oral Contraceptive: Ovcon Fe®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Immunogenicity and Safety of OVX836 Influenza Vaccine 480μg
Status: NOT_YET_RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: OVX836 480µg|BIOLOGICAL: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)
Status: COMPLETED
Conditions: Glycogen Storage Disease Type II
Interventions: DEVICE: RMT therapy using modified RMT device|DEVICE: Sham-RMT therapy using modified RMT device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relative Bioavailability and Effect of Food Study With an Oral Mini-tablet Formulation of Filgotinib in Healthy Subjects
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Filgotinib|DRUG: Filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscle-invasive Bladder Cancer
Interventions: OTHER: Whole-body FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Behavioral Pain Medicine for Orthopedic Trauma Surgery Patients
Status: COMPLETED
Conditions: Orthopedic Trauma Surgery Patients
Interventions: BEHAVIORAL: Perioperative Digital Behavioral Pian Medicine "My Surgical Success"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Status: UNKNOWN
Conditions: Disability Physical|Brain Injuries|Stroke|Spinal Cord Injuries|Multiple Sclerosis|Paralysis
Interventions: DEVICE: Using adaptive device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diagnostic Aids for Detection and Diagnosis of Oral Cancer
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: BEHAVIORAL: Questionnaire|DEVICE: POS + PS2 + VELscope|PROCEDURE: Oral Brush Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Entospletinib|DRUG: Daunorubicin|DRUG: Cytarabine|DRUG: Decitabine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Assessment of Nutrition and Dietary Intervention in Hypermobile Ehlers Danlos Syndrome
Status: COMPLETED
Conditions: Hypermobile Ehlers-Danlos Syndrome|Irritable Bowel Syndrome|Functional Gastrointestinal Disorders
Interventions: BEHAVIORAL: Dietician advice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-center Prospective Randomized Controlled Study on Clinical and Radiographic Analysis of ProDisc-C Vivo
Status: NOT_YET_RECRUITING
Conditions: Disk Degeneration|Cervical Disc Disease
Interventions: PROCEDURE: ProDisc-C vivo|PROCEDURE: Anterior cervical discectomy fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combined Ionizing Radiation and Ipilimumab in Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Ipilimumab|RADIATION: Radiotherapy (IMRT or 3-D CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bedside Nursing Handovers in the Surgical Context
Status: COMPLETED
Conditions: General Surgery
Interventions: BEHAVIORAL: Education for improving handovers quality|BEHAVIORAL: Education for improving bedside handovers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Controlled Study Comparing REPaiR® and MIST Therapies for Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DEVICE: MIST (minimally invasive surgical therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal Failure
Status: RECRUITING
Conditions: Acute Kidney Injury|Fluid Overload
Interventions: PROCEDURE: Fluid balance negativation|PROCEDURE: Body weight Stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer
Status: RECRUITING
Conditions: Microsatellite Stable Colorectal Cancer|Pancreatic Cancer|MSI High Colorectal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Group (PENG) Block for Congenital Hip Dislocation Surgery
Status: COMPLETED
Conditions: Congenital Hip Dysplasia
Interventions: DRUG: Saline Solution|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Drug-Drug Interaction Between ASP1941 and Miglitol
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: Miglitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase 2 Bunionectomy HTX-011 Administration Study
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: HTX-011|DEVICE: Luer Lock applicator|DEVICE: Vial access device|DRUG: aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sunitinib Malate in Treating Patients With Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: sunitinib malate|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Elacytarabine Versus Investigator's Choice in Patients With Late Stage Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Elacytarabine|DRUG: Investigator's Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Melanoma Vaccine for High Risk or Low Residual Disease Patients
Status: UNKNOWN
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: A2/4-1BBL melanoma vaccine|PROCEDURE: DNP sensititzation|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection
Status: RECRUITING
Conditions: HPV Infection|LSIL, Low-Grade Squamous Intraepithelial Lesions|HSIL, High-Grade Squamous Intraepithelial Lesions|Virus Integration
Interventions: OTHER: Follow up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strategies for Assessment of Fluid Overload in Acute Decompensated Heart Failure
Status: TERMINATED
Conditions: Heart Failure|Decompensated Heart Failure
Interventions: OTHER: Lung ultrasound|OTHER: Echocardiography|OTHER: Peripheral venous pressure|OTHER: Magnetic resonance imaging|OTHER: Pulmonary scintigraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flotetuzumab for the Treatment of Pediatric Recurrent or Refractory Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|BIOLOGICAL: Flotetuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Bupropion HCI 300 mg Extended-Release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Bupropion HCI 300 mg Extended-Release Tablets EON|DRUG: WELLBUTRIN XL 300 mg Extended-Release Tablets GlaxoSmithKline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy Supplementation and Gestational Diabetes
Status: COMPLETED
Conditions: Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: Soy Group (Soy Protein + Isoflavones)|DIETARY_SUPPLEMENT: Control Group (Minimize Soy Intake)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
Status: COMPLETED
Conditions: Cancer Survivor|Depression|Gastrointestinal Complications|Male Erectile Disorder|Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment|Urinary Complications
Interventions: BEHAVIORAL: telephone-based intervention|OTHER: educational intervention|OTHER: partner-assisted coping skills training|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Blood Loss During Cesarean Section by Topical Versus IV Tranexamic Acid
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: OTHER: normal saline arm group|DRUG: intravenous tranexamic acid|DRUG: Topical tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Montelukast on Asthma Control in Overweight/Obese Atopic Asthmatics
Status: COMPLETED
Conditions: Asthma|Obesity|Inflammation
Interventions: DRUG: Montelukast|DRUG: Placebo|DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Ranibizumab Treatment of Central Retinal Vein Occlusion With Macular Edema
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab (Lucentis )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis
Status: COMPLETED
Conditions: Candidiasis, Oral
Interventions: DRUG: micafungin|DRUG: caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Coronary Artery Bypass Graft (CABG) Surgery on Skeletal Muscle Mass and Insulin Sensitivity, Followed by Exercise Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Treatment|BEHAVIORAL: Minimal Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Status: RECRUITING
Conditions: Pain|Amputation
Interventions: DRUG: 10 mL 2% lidocaine|DRUG: 10 mL preservative free saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TNT to Increase the Clinical Complete Response Rate for Distal LARC
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer|Rectal Cancer Stage II|Rectal Cancer Stage III|Chemoradiation
Interventions: DRUG: Capecitabine, Oxaliplatin|RADIATION: External beam radiotherapy|PROCEDURE: Surgery|OTHER: Watch and wait strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer Metastatic
Interventions: BIOLOGICAL: HB-302/HB-301 Alternating 2-Vector Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn
Status: COMPLETED
Conditions: Postprandial Heartburn
Interventions: DEVICE: IQP-LH-101 tablet|DEVICE: IQP-LH-101 liquid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Research of Unified Protocol for the Treatment of Common Mental Disorders in Adolescents in Hong Kong
Status: COMPLETED
Conditions: Depressive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Unified protocol for adolescents (UP-A)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Bioavailability Study of Zonisamide Capsules
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zonisamide 100 mg Capsule|DRUG: Zonisamide (Zonegran®) 100 mg Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Antidiabetic Medications on the Postprandial State in Prediabetes
Status: COMPLETED
Conditions: Prediabetes|Obesity
Interventions: DRUG: Exenatide|DRUG: Saxagliptin|DRUG: Exenatide extended-release (ER)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Whey Protein Supplementation and Resistance Exercise on Muscle Parameters in Older Adults
Status: COMPLETED
Conditions: Mobility Limitation
Interventions: DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Maltodextrin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ReMARK: Addressing Disparities in Rural Communities to Increase the HPV Vaccine Recommendation Effectiveness
Status: NOT_YET_RECRUITING
Conditions: Papillomavirus Vaccines
Interventions: BEHAVIORAL: Brief training|BEHAVIORAL: Parent-targeted motivational aids|BEHAVIORAL: Healthcare access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Meal Skipping on Macronutrient Oxidation and Glucose Metabolism Under Isocaloric Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Breakfast skipping|BEHAVIORAL: Dinner skipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Mycophenolate Mofetil Combined With Glucocorticoid Therapy in Relapse Vogt-Koyanagi-Harada Disease
Status: RECRUITING
Conditions: Vogt-Koyanagi-Harada Disease|Mycophenolate Mofetil
Interventions: DRUG: Mycophenolate Mofetil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood
Status: COMPLETED
Conditions: Cognitive Therapy|Depression, Postpartum|Mental Health|Depression|Depressive Disorder|Anxiety|Telemedicine
Interventions: BEHAVIORAL: Use of smartphone application (app)|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children
Status: RECRUITING
Conditions: White Spot Lesion of Tooth
Interventions: DRUG: Self-assembling peptide (P11-4)|DRUG: CPP-ACFP|DRUG: Resin infiltration|OTHER: Control Group, No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Fat Grafting Augmentation in Chinese Women
Status: COMPLETED
Conditions: Breast Implantation
Interventions: PROCEDURE: Autologous Fat Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: Lucerastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
Status: COMPLETED
Conditions: Pain, Postoperative|Analgesia
Interventions: DRUG: paracetamol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-561|DRUG: Placebo|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammation and Insulin Resistance in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
Status: COMPLETED
Conditions: Refractive Errors|Astigmatism
Interventions: DEVICE: Lehfilcon A toric contact lenses|DEVICE: Comfilcon A toric contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Transarterial Chemoinfusion (TAI) Combine Toripalimab in Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: Transarterial Chemoinfusion (TAI) Combine Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic/Pharmacokinetic Study of AQW051 in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AQW051|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Major Nutrients Deficiency in Diabetic Patient Before and After Bariatric Surgery
Status: UNKNOWN
Conditions: Diabetic Patient Before and After Bariatric Surgery|Nutrition Deficiency(VitB1 VitB12.Ca.Fe)
Interventions: PROCEDURE: bariatric surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Sacropexy: Comparison of Mesh Attachment
Status: UNKNOWN
Conditions: Vaginal Vault Prolapse
Interventions: PROCEDURE: laparoscopic sacropexy with mid vaginal attachment|PROCEDURE: laparoscopic sacropexy with caudal vaginal attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Hygiene and Relaxation Intervention to Improve Sleep and Fatigue for Children Receiving Maintenance Chemotherapy
Status: COMPLETED
Conditions: Sleep|Fatigue|Acute Lymphoblastic Leukemia
Interventions: BEHAVIORAL: Sleep Hygiene and Relaxation Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Micropulsed Laser in Patients With Macular Oedema in Retinal Dystrophies
Status: RECRUITING
Conditions: Macular Edema|Inherited Retinal Dystrophy|Laser Retinopathy
Interventions: DEVICE: subthreshold treatment with micropulsed laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Infused Donor T Regulatory Cells in Steroid Dependent/Refractory Chronic GVHD
Status: COMPLETED
Conditions: Graft Versus Host Disease|Allogeneic Hematopoietic Cell Transplant Recipient
Interventions: BIOLOGICAL: Regulatory T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Active Isolated Stretch and Post Isometric Relaxation for Hamstring Flexibility.
Status: COMPLETED
Conditions: Hamstring Tightness
Interventions: OTHER: Active Isolated Stretch|OTHER: Post Isometric Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous Pump
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: E-TRANS Fentanyl hydrochloride; Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Cognitive Behavioral Therapy and Physiotherapy in Persons With Chronic Widespread Pain
Status: COMPLETED
Conditions: Pain, Chronic|Widespread Chronic Pain
Interventions: BEHAVIORAL: Internet-based cognitive behavioral therapy + physiotherapy|BEHAVIORAL: Physiotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Semaglutide in Advanced Lung Disease
Status: RECRUITING
Conditions: Obesity|Interstitial Lung Disease|Chronic Obstructive Pulmonary Disease|Sarcoidosis, Pulmonary|Pulmonary Hypertension
Interventions: DRUG: Semaglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-A )
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: COMBINATION_PRODUCT: Emergency Stroke Unit based on 0.23-T MRI|COMBINATION_PRODUCT: Standard stroke unit adherent to guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety and Tolerability Study of TMC435 in Genotype 1 Hepatitis C-infected Patients Who Relapsed After Previous Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435|DRUG: Placebo|DRUG: Peginterferon alpha-2a (PegIFN alpha-2a)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sustainable-psycho-nutritional Intervention Program and Its Effects on Health Outcomes and the Environment
Status: ACTIVE_NOT_RECRUITING
Conditions: Gut Microbiota|Hyperglycemia|Hypercholesterolemia|HDLC|Hypertriglyceridemia|Eating Behavior|Body Composition|Acanthosis Nigricans|Blood Pressure|Food Intake|Physical Activity|Diet Quality
Interventions: BEHAVIORAL: Sustainable diet promotion through behavioral change intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Production of Vitamin D Metabolites by UV-radiation From Solar Bed
Status: COMPLETED
Conditions: Production of Vitamin D in Skin When Exposed to UV-B by Solar Bed.
Interventions: RADIATION: UV radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Relapsed/Refractory Multiple Myeloma (rrMM) With Pomalidomide in Clinical Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Bortezomib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ReStOre@Home: Feasibility Study of a 12-week Multidisciplinary Telehealth Rehabilitation Programme for Survivors of Upper Gastrointestinal (UGI) Cancer
Status: COMPLETED
Conditions: Oesophageal Cancer|Gastric Cancer
Interventions: OTHER: Multidisciplinary rehabilitation programme delivered via telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Neratinib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficiency and Satisfaction of Pharmacist Giving Patient-centred Advice on Telephone Consultation in TB Patients: Experience of the COVID-19 Pandemic
Status: UNKNOWN
Conditions: TB - Tuberculosis|Patient Satisfaction
Interventions: BEHAVIORAL: Patient-centred advice on Telephone Consultation in TB Patients:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Corticosteroid vs Platelet-Rich Plasma Intra-articular Injections in the Treatment of Knee Osteoarthritis.
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: Triamcinolone|OTHER: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Cefprozil 250 mg/ 5mL Powder For Oral Suspension Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CEFPROZIL FOR ORAL SUSPENSION USP 250 mg/ 5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intermittent Hormonal Therapy With Leuprorelin and Flutamide in the Treatment of Stage D2 or TxNxM1b,c
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Leuprorelin|DRUG: Flutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Caelyx in Combination With Carboplatin in Patients With Ovarian Cancer Recurrent Within Six to Twelve Months After Initial Carboplatin and Paclitaxel Chemotherapy (P03625)
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Pegylated Liposomal Doxorubicin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphate Microvascular Study
Status: UNKNOWN
Conditions: End Stage Renal Disease|Hyperphosphatemia
Interventions: OTHER: Withholding standard phosphate binder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Partially HLA-matched Third Party Antigen Specific T-cells for Infection Post-stem Cell or Solid Organ Transplantation
Status: UNKNOWN
Conditions: CMV Infection|EBV|Adenovirus
Interventions: BIOLOGICAL: Virus specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study of VRDN 001 in Healthy Volunteers and Persons With Thyroid Eye Disease (TED)
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: VRDN-001 Phase 1/2 MAD (HV and TED)|DRUG: VRDN-001 Phase 3 Cohort (THRIVE)|DRUG: VRDN-001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Cancer Metastatic
Interventions: OTHER: Counseling Tool|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)
Status: COMPLETED
Conditions: Gastroesophageal Reflux|GERD|GORD
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yield & Specimen Adequacy of Flex 19 G vs 22 G EBUS Needle - A Randomized Controlled Trial
Status: COMPLETED
Conditions: Mediastinal Lymphadenopathy|Hilar Lymphadenopathy
Interventions: PROCEDURE: EBUS-TBNA using 22 G EBUS-FNB Device OR 19 G EBUS-FNA needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Sedentary Time in Chronic Low Back Pain: Sedentary Intervention Using Motivational Interviewing and Technology
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Intervention to Reduce Sedentary Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation on Molar Verticalization With Mini-implant
Status: COMPLETED
Conditions: Orthodontic Appliances|Low-Level Light Therapy
Interventions: PROCEDURE: Placement of the mini-implant and verticalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological Conditions
Status: COMPLETED
Conditions: Chronic Troublesome Sialorrhea|Parkinson's Disease|Post-stroke|Traumatic Brain Injury
Interventions: DRUG: IncobotulinumtoxinA (100 Units)|DRUG: IncobotulinumtoxinA (75 Units)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two High-intensity Gait Training Interventions on Contraversive Pushing Behaviors in Individuals Poststroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Body-weight-supported treadmill|DEVICE: Ekso Bionics EksoNR exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naltrexone in Borderline Personality Disorder
Status: TERMINATED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Interventional Study Evaluating the Feasibility and Safety of the Esophageal Cooling Device
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Esophageal Cooling Device (ECD), manufactured by Advanced Cooling Therapy, Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: TP-38|DRUG: TP38
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Irradiation to the Contralateral Breast for BCAs Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Prophylactic contralateral breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib Study of Alpelisib With Cisplatin in Patients With HPV+ Solid Tumor Malignancies
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Alpelisib|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist
Status: COMPLETED
Conditions: Fibrosis|Kidney Failure|Renal Insufficiency
Interventions: DRUG: Gadopentetate dimeglumine (Magnevist, BAY86-4882)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Noninvasive Perioperative Monitoring of Arterial Stiffness, Volume and Nutritional Status in Stable Renal Transplant Recipients
Status: UNKNOWN
Conditions: Arterial Calcification|Aortic Stiffness|High Blood Pressure|Kidney Transplantation
Interventions: DEVICE: BR-102 plus PWA|DEVICE: Tanita MC780 MA S
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p