pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Peginesatide Injection for the Maintenance Treatment of Anemia in Peritoneal Dialysis Participants Previously Treated With Epoetin.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meta-analyses of Fructose and Cardiometabolic Risk
Status: UNKNOWN
Conditions: Dyslipidemia|Diabetes|Prediabetes|Dysglycemia|Overweight|Obesity|Gout|Hypertension|Non-alcoholic Fatty Liver Disease|Metabolic Syndrome|Cardiovascular Disease
Interventions: OTHER: Dietary fructose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study On An Immunostimulant Antibody In Combination With Chemotherapy For Advanced Cancer Of The Pancreas
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: BIOLOGICAL: monoclonal antibody|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feedback on Perioperative Temperature Management and Patient Outcomes: Three-arm Trial to Compare Feedback
Status: COMPLETED
Conditions: Surgical Site Infections|Hypothermia
Interventions: BEHAVIORAL: Benchmarked Feedback|BEHAVIORAL: Ranked Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Consistency of StaphVAX Manufacturing Lots
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: BIOLOGICAL: S. aureus Type 5 & 8 Capsular Polysaccharide Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Randomized Multicenter Cross-over Study to Compare the Effect of Physioneal 35 to 40 on the Protein Metabolism
Status: TERMINATED
Conditions: Endstage Renal Disease
Interventions: DRUG: Physioneal 35|DRUG: Physioneal 40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Inflation Methods of the Ambú Auraonce™ and Its Adverse Effects
Status: COMPLETED
Conditions: Laryngeal Mask Airway
Interventions: DEVICE: intracuff pressure measurement|DEVICE: intracuff pressure measurement|DEVICE: intracuff pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Carcinoma|Breast Tumors|Malignant Neoplasm of Breast
Interventions: DRUG: Paclitaxel|DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Communicational Program "Trust" to Improve Adherence to Medications
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Infarction|Cardiovascular Diseases
Interventions: OTHER: Standard outpatient observation|BEHAVIORAL: Communicational program "Trust"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Study of AMV564 in Patients With Intermediate or High-Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: DRUG: AMV564 14-Day CIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Evidence-based Information About PSA Testing on Prostate Cancer Screening Decisions
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Evidence-based information|OTHER: Patient Decision Aid|OTHER: Sham information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar
Status: UNKNOWN
Conditions: Mastication Disorder
Interventions: PROCEDURE: autologous platlet rich fibrin|PROCEDURE: one side in control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease
Status: TERMINATED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Vehicle|OTHER: Sham|DRUG: Cyclosporine New Ophthalmic Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease|Atherosclerosis
Interventions: DEVICE: Xtreme Touch - Neo sirolimus coated PTA balloon catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Body Composition Via Dual-energy X-ray Absorptiometry Bone Densitometry
Status: COMPLETED
Conditions: Osteodensitometry
Interventions: DEVICE: Whole body exam using the "Discovery A"|DEVICE: First whole body exam using the "Stratos DR"|DEVICE: Second whole body exam using the "Stratos DR"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Imatinib in Dermatofibrosarcoma Protuberans
Status: COMPLETED
Conditions: Dermatofibrosarcoma Protuberans
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study Evaluating How Quickly And To What Extent The 14-Carbon-SAM-531 Is Absorbed/Converted/Eliminated In Male Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: SAM-531
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dietary Modulation of Hepatic Lipase (LIPC) -514 C/T Variant Associations With Lipids and Glucose
Status: COMPLETED
Conditions: Dyslipidemia|Impaired Glucose Tolerance
Interventions: OTHER: High-fat diet|OTHER: Low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypotension Prediction With HPI Algorithm During Major Gynecologic Oncologic Surgery
Status: COMPLETED
Conditions: Intraoperative Hypotension|Hemodynamic Instability|Gynecologic Cancer
Interventions: DEVICE: HPI - hypotension prediction index|DEVICE: GDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lactobacillus Reuteri in Premature Infants
Status: TERMINATED
Conditions: Premature Infant Disease
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Weaning of Nasal Continuous Positive Airway Pressure (CPAP)
Status: COMPLETED
Conditions: Preterm Neonates
Interventions: PROCEDURE: Gradual weaning from Nasal CPAP in preterm neonates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
Status: RECRUITING
Conditions: Locoregional Recurrence|Hormone Receptor-positive Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Fulvestrant|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients with Metastatic Neuroendocrine Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Neuroendocrine Neoplasm|Metastatic Neuroendocrine Neoplasm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Performance Profile of the Colospan Device CG-100 in Patients Undergoing Colorectal Surgery
Status: COMPLETED
Conditions: Gastrointestinal Anastomosis
Interventions: DEVICE: CG-100 device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Cardiac Injections of iMP Cells During CABG Surgery
Status: UNKNOWN
Conditions: Myocardial Fibrosis
Interventions: BIOLOGICAL: iMP cells|OTHER: Control injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Gastric Adenocarcinoma|Esophageal Adenocarcinoma|Castration Resistant Prostate Adenocarcinoma|Soft Tissue Sarcoma|Ovarian Adenocarcinoma|Advanced Well-differentiated Neuroendocrine Tumors|Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: PDR001|BIOLOGICAL: LAG525
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin-Myocardial Infarction Study (AMIS)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Safety Tolerability and Pharmacokinetics of AZD4831 to Treat Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: AZD4831|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs
Status: RECRUITING
Conditions: Inguinal Hernia|Ventral Hernia
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Treatment With VENARUS® on the Level of Monocyte Chemoattractant Protein 1 in Varicose Veins Blood
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DRUG: Diosmin / Hesperidin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-Myofascial Release of the Upper Cervical Muscles
Status: RECRUITING
Conditions: Suboccipital Muscles|Superficial Back Line|Myofascial Release
Interventions: DEVICE: Occipivot suboccipital pillow self-myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide for Idiopathic Pulmonary Hemosiderosis in Children
Status: RECRUITING
Conditions: Idiopathic Pulmonary Hemosiderosis|Leflunomide
Interventions: DRUG: Leflunomide|DRUG: Steroid Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab and Triamcinolone Associated to Laser Photocoagulation for Diabetic Macular Edema(IBeTA)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Laser photocoagulation|DRUG: Intravitreal triamcinolone|DRUG: Intravitreal bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling
Status: COMPLETED
Conditions: Fibrosing Alopecia|Frontal Fibrosing Alopecia|Central Centrifugal Cicatricial Alopecia
Interventions: DEVICE: SOL Nova Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MD2, Cystatin C and DNA Methylation Tags as Serum Biomarkers for POCD.
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: Serum biomarker tests|BEHAVIORAL: Neuropsychological battery tests|PROCEDURE: Cardiac surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Blood-Borne Infections|Communicable Disease|Infections|Sexually Transmitted Diseases, Bacterial|Sexually Transmitted Diseases, Viral|RNA Virus Infections|Virus Disease|Syphilis|Neisseria Gonorrheae Infection|Chlamydia Trachomatis Infection
Interventions: DRUG: PrEP|DEVICE: STI testing|BEHAVIORAL: Assisted partner notification|DIAGNOSTIC_TEST: Acute HIV testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Visual Sputum Suctioning System Tests in Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Ineffective Airway Clearance|Respiratory Tract Hemorrhage
Interventions: DEVICE: Visual Sputum Suctioning System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of ONCO-DOX in Locally Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Hepatoma|Liver Cell Carcinoma
Interventions: DEVICE: DEB-TACE|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Tolerability of Single Ascending Dose (SAD) SLV-351 in Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: SLV-351
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension
Status: COMPLETED
Conditions: Cirrhosis|Portal Hypertension
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Carbohydrate Diet vs. High Carbohydrate Diet in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Low carbohydrate diet|OTHER: High carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: GSK3179106|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Corticospinal Excitability to Improve Functional Recovery
Status: COMPLETED
Conditions: Spinal Cord Injuries|Tetraplegia
Interventions: OTHER: bihemispheric transcranial pulsed current stimulation (tPCS)|OTHER: unihemispheric transcranial pulsed current stimulation (tPCS)|OTHER: bihemispheric transcranial direct current stimulation (tDCS)|OTHER: unihemispheric transcranial direct current stimulation (tDCS)|OTHER: sham-control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Volatile Organic Compounds as Markers of Acute Rejection in Lung Transplant
Status: UNKNOWN
Conditions: Transplant; Complication, Rejection
Interventions: DEVICE: eNose (electronic nose)|DEVICE: Spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of an Antioxidant-rich Diet During Moderate Altitude Training
Status: COMPLETED
Conditions: Oxidative Stress|Adaptation Reaction|Inflammation
Interventions: OTHER: Antioxidant-rich snacks|OTHER: Control snacks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Developing an eLearning Program in Helping Spanish and Portuguese Speaking Cancer Care Providers During Tobacco Use Counselling
Status: COMPLETED
Conditions: Health Care Provider
Interventions: OTHER: Internet-Based Intervention|OTHER: Meeting|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Strategy for Refractory Schizophrenia: Drug Interaction Between Clozapine and Fluvoxamine
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: clozapine plus fluvoxamine|DRUG: clozapine plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Comparative Study of Cell Transfer Therapy Using CD8+-Enriched Short-Term Cultured Anti-Tumor Autologous Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Compared to High-Dose Aldesleukin in M...
Status: COMPLETED
Conditions: Skin Cancer|Melanoma|Metastatic Melanoma
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: CD8 enriched Young TIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection
Interventions: DRUG: FIO2=0.8|DRUG: FIO2=0.33
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
Status: COMPLETED
Conditions: Male Breast Cancer|Neurotoxicity|Peripheral Neuropathy|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Immediate and Long-term Outcomes of the Disease in Patients With Left Ventricular Aneurysm Complicated and Uncomplicated by Thrombosis After Transmural Myocardial Infarction, According to the Hospital Registry: SIBYL
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: OTHER: Not Provided
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Diclofenac Sodium Gel in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Diclofenac Topical Sodium Gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: Crackers/pasta with added faba bean protein concentrate|DIETARY_SUPPLEMENT: Crackers/pasta with added faba bean protein isolate|DIETARY_SUPPLEMENT: Crackers/pasta with added faba bean starch|DIETARY_SUPPLEMENT: Crackers/pasta with added faba bean flour|DIETARY_SUPPLEMENT: Crackers/pasta with no faba bean fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiovascular MRI and Cardiopulmonary Exercise Capacity After Neonatal ASO) in Young Adults
Status: UNKNOWN
Conditions: Transposition of the Great Arteries|Artery Switch Operation
Interventions: OTHER: Correlation Heart Magnetic Resonance Imaging at rest and stress with Cardiopulmonary stress test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Performance Study of the RELIANCE 4-Front Passive Fixation Lead
Status: COMPLETED
Conditions: Tachycardia|Ventricular Fibrillation|Ventricular Flutter
Interventions: DEVICE: RELIANCE 4-FRONT™ Passive Fixation lead implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Levels of Tablet and Liquid Forms of Lamivudine, Nevirapine, and Stavudine in HIV Infected Thai Children
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine, nevirapine, and stavudine fixed-dose tablet|DRUG: Lamivudine|DRUG: Nevirapine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia|Memory Loss|Cognitive Impairment
Interventions: DRUG: ladostigil hemitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin Cancer
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: [68Ga]PSMA|DIAGNOSTIC_TEST: PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TVT Versus Bulkamid®-Injections in Treatment of Stress Urinary Incontinence
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Stress Incontinence
Interventions: DEVICE: Bulkamid|DEVICE: Tension-free Vaginal Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 in Recurrent/Metastatic Nasopharyngeal Carcinoma Who Have Received Previous At Least Two Lines of Chemotherapy.
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Adherence and Fatigue in Iron Deficiency
Status: NOT_YET_RECRUITING
Conditions: Fatigue|Adherence, Medication
Interventions: OTHER: Patient training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: PF-3512676 + Paclitaxel + Carboplatin|DRUG: Paclitaxel + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Invasive Breast Carcinoma|Progesterone Receptor Negative|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tiotropium Compared to Salmeterol and Placebo in Patients With Chronic Obstructive Bronchitis (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium inhalation powder capsules|DRUG: Salmeterol inhalation aerosol|DRUG: Placebo inhalation aerosol|DRUG: Placebo inhalation powder capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin-Prevention in Labor Use Study (A-PLUS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Maternal Death|Maternal Infections Affecting Fetus or Newborn|Neonatal SEPSIS|Maternal Sepsis During Labor|Neonatal Death|Postpartum Sepsis
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Three Different Treatment Options for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Traditional dietary advice and low FODMAP content|OTHER: Low carbohydrate diet|OTHER: Optimized Medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Effect of Repeated Exposure, Flavor-Flavor and Flavor-Nutrient Learning on Vegetable Acceptance in Infants
Status: COMPLETED
Conditions: Development of Eating Behavior
Interventions: BEHAVIORAL: Repeated consumption of basic artichoke purée.|BEHAVIORAL: Repeated consumption of sweet artichoke purée.|BEHAVIORAL: Repeated exposure to fat artichoke purée.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Patients With Statin Myopathy Using an N of 1 Trial Design
Status: COMPLETED
Conditions: Statin Myopathy
Interventions: DRUG: Individual-specific statin causing myopathy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cixutumumab in Treating Patients With Metastatic Melanoma of the Eye
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Ciliary Body and Choroid Melanoma, Small Size|Iris Melanoma|Metastatic Intraocular Melanoma|Recurrent Intraocular Melanoma|Stage IV Intraocular Melanoma
Interventions: BIOLOGICAL: Cixutumumab|OTHER: Laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: TAR-200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pharmacokinetic Parameters and Safety Profiles Between AD-109 and AD-1091
Status: COMPLETED
Conditions: Embolism and Thrombosis
Interventions: DRUG: Rivaroxaban 18mg Oral Tablet|DRUG: Rivaroxaban 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Purandare's Cervicopexy Versus Abdominal Sacral Hysteropexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Modified Purandare cervicopexy|PROCEDURE: Abdominal sacral hysteropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine (VIRAMUNE) and Ethinyl Estradiol/Norethindrone in HIV-1 Infected Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: EE/NET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CN201
Status: RECRUITING
Conditions: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: CN201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel Activity in Patients With Advanced AdrenoCortical-Carcinoma Progressing After Previous Chemotherapy Lines
Status: UNKNOWN
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer
Status: TERMINATED
Conditions: Neoplasms|Ovarian Neoplasms|Fallopian Tube Neoplasms|Primary Peritoneal Neoplasm
Interventions: BIOLOGICAL: KHK2866|DRUG: Gemcitabine and Carboplatin|DRUG: paclitaxel|DRUG: pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Gastroenterostomy Versus Surgical Gastrojejunostomy
Status: NOT_YET_RECRUITING
Conditions: Malignant Gastric Outlet Obstruction
Interventions: PROCEDURE: EUS Gastrojejunostomy|PROCEDURE: Surgical Gastrojejunostomy|OTHER: Gastric Outlet Obstruction Scoring System (GOOSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Generalizability of REDUCE-IT Results to People of South Asian Descent With Atherosclerotic Cardiovascular Disease in Canada (REDUCE-IT Canada SA)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atherosclerotic Cardiovascular Disease|Myocardial Infarction|Coronary Heart Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral Cavity
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma, Head And Neck|Squamous Cell Carcinoma Mouth|Resectable Squamous Cell Carcinoma of Oral Cavity
Interventions: DRUG: Mocetinostat|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Motilitone Therapy on Health-related Quality of Life in PD Patients With Gastrointestinal Symptoms
Status: COMPLETED
Conditions: Parkinson Disease|Dyspepsia
Interventions: DRUG: DA-9701|DRUG: DA-9701 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of APD421 as PONV Treatment (no Prior Prophylaxis)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: APD421|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Educational Interventions Targeting Beliefs About Human Papillomavirus (HPV)
Status: ENROLLING_BY_INVITATION
Conditions: Beliefs|HPV|Education, Medical|Intervention
Interventions: BEHAVIORAL: Misbeliefs about HPV training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia
Status: COMPLETED
Conditions: Post-operative Analgesia
Interventions: DRUG: Paracetamol injection|DRUG: Normal Saline injection|DRUG: Morhpine PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine, Lenalidomide and DLI as Salvage Therapy for MDS, CMML and sAML Relapsing After Allo-HSCT
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Lenalidomide|DRUG: Azacitidine|BIOLOGICAL: Donor Lymphocyte Infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: TmPSMA-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy and Reaction Time in Hemophilia
Status: COMPLETED
Conditions: Hemophilia Arthropathy
Interventions: OTHER: Home exercise|OTHER: Manual therapy|DEVICE: Neuromuscular electrical stimulation|OTHER: Supervised exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: GWP42003-P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Decision Support System|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of mCIMT and Bimanual Training
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Modified Constraint-Induced Movement Therapy|OTHER: Bimanual Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traumatic Brain Injury Peripheral Nerve Study
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Eon-mini IPG (implantable pulse generator)|DEVICE: Eon-mini IPG (implantable pulse generator)|DEVICE: Eon-mini IPG (implantable pulse generator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Once/Daily Administered GLP/1 Receptoragonist (Lixisenatide) in Combination With Basal Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Pancreatic Cancer
Interventions: DRUG: KRAS Vaccine with Poly-ICLC adjuvant|DRUG: Balstilimab|DRUG: Botensilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive Disorder
Status: COMPLETED
Conditions: Treatment Resistant Major Depressive Disorder
Interventions: DRUG: AXS-05|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RK0202 in Oral Mucositis
Status: COMPLETED
Conditions: Mouth Diseases|Mouth Ulcers|Oral Mucositis|Head and Neck Cancer
Interventions: DRUG: RK-0202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Non-intervention Fiberoptic Bronchoscopy Study of Remazolam Toluene Sulfonate for Injection Under General Anesthesia and Fiberoptic Bronchoscopy
Status: UNKNOWN
Conditions: General Anesthesia and Bronchoscopy Sedation
Interventions: DRUG: Remimazolam Tosilate for Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effect of Food on the Pharmacokinetics of Surfolase CR Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Surfolase CR|DRUG: Surfolase CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Minocycline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Comparing Standard Anastomosis Closure Technique to Standard Closure Techniques Plus Sylys® Surgical Sealant
Status: TERMINATED
Conditions: Colorectal and Ileorectal Anastomosis|Colocolic and Ileocolic Anastomosis|Coloanal and Ileoanal Anastomosis
Interventions: DEVICE: Sylys® Surgical Sealant|PROCEDURE: Stapled Anastomosis Colectomy Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide as Chemoprevention in Treating Patients With High-Risk, Early-Stage B-Cell Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: B-cell Chronic Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Stage 0 Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia
Interventions: DRUG: lenalidomide|OTHER: laboratory biomarker analysis|PROCEDURE: lymph node biopsy|PROCEDURE: bone marrow aspiration|OTHER: pharmacological study|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever
Status: RECRUITING
Conditions: Familial Mediterranean Fever|FMF
Interventions: BIOLOGICAL: RPH-104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of Methylphenidate HCl Extended-release Tablets in Adults With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: methylphenidate hydrochloride extended-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3202626 on Disease Progression in Participants With Mild Alzheimer's Disease Dementia
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: LY3202626|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of School Based Intervention on Psychosocial Factors Associated With Trauma Among Adolescents
Status: NOT_YET_RECRUITING
Conditions: Interventional Study
Interventions: BEHAVIORAL: Support for Students exposed to Trauma Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Session Compared to Multiple Sessions of Education and Exercise for Older Adults With Spinal Pain in an Advanced Practice Physiotherapy Model of Care
Status: COMPLETED
Conditions: Musculoskeletal Pain Disorder|Spinal Pain
Interventions: OTHER: Single session of education and exercise provided by an advanced practice physiotherapist.|OTHER: Multiple session of education and exercise provided by an advanced practice physiotherapist.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Examines the Feasibility, Safety and Benefits of Using a Specific Suspension Walking Device for Patients With Neurological Damage
Status: COMPLETED
Conditions: Stroke|Traumatic Brain Injury|Incomplete Cervical Spinal Cord Injury|Other Brain Injuries
Interventions: OTHER: Suspension walking training
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VISIODOL: Validation of the VISIODOL® Scale
Status: TERMINATED
Conditions: Visual Deficiency|Congenital Blindness|Acquired Blindness
Interventions: DIAGNOSTIC_TEST: VISIODOL® (Diagnostic tool)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: rabeprazole|DRUG: rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Full-Thickness Resection In Colon
Status: UNKNOWN
Conditions: Colon Neoplasm, Malignant|Colo-rectal Cancer|Colonic Cancer|Colonic Adenoma|Colorectal Cancer|Colorectal Neoplasms|Colorectal Adenocarcinoma|Colon Polyp|Colon Lesion|Colon Neoplasm
Interventions: PROCEDURE: Endoscopic full-thickness resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficient Anterior Shoulder Ultrasound Reduction Multicenter Prospective Randomized Trial
Status: TERMINATED
Conditions: Shoulder Dislocation
Interventions: DIAGNOSTIC_TEST: X-Ray|DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Paclitaxel, Nab-paclitaxel, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|HER2/Neu Positive|Progesterone Receptor Negative|Progesterone Receptor Positive|Recurrent Breast Carcinoma|Stage IIIC Breast Cancer AJCC v6|Stage IV Breast Cancer AJCC v6 and v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Ixabepilone|OTHER: Laboratory Biomarker Analysis|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RELAXaHEAD for Headache Patients (Phase I)
Status: COMPLETED
Conditions: Headache|Migraine|Multiple Sclerosis
Interventions: BEHAVIORAL: RELAXaHEAD app|BEHAVIORAL: Monitored Usual Care (MUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Efficacy And Safety of PD-1 + IL-2 Combined With Capox Treatment After Loop Colostomy Surgery in Left-sided Colorectal Cancer Patients Complicating Acute Obstruction
Status: NOT_YET_RECRUITING
Conditions: Left-sided Colorectal Cancer Complicating Acute Obstruction
Interventions: DRUG: Tislelizumab + IL-2 Combined with Capox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: Fianlimab|DRUG: Cemiplimab|DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Features and Airways Inflammation in Never Smokers and Smokers With COPD
Status: COMPLETED
Conditions: COPD|Airway Obstruction|Inflammation
Interventions: DIAGNOSTIC_TEST: Analysis of induced sputum|DIAGNOSTIC_TEST: Lung Function test|DIAGNOSTIC_TEST: Enzyme-linked Immunosorbent Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Evaluate the Safety, Tolerability and Immunogenicity of the Recombinant MVA BN® RSV Vaccine
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: MVA BN RSV|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION