pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Epidural Anesthesia-analgesia and Long-term Outcome
Status: COMPLETED
Conditions: Elderly|Malignant Tumor|Surgical Resection|Epidural Anesthesia|Long-term Outcome
Interventions: DRUG: Combined epidural-general anesthesia|DRUG: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Pain, Postoperative|Pain, Acute Postoperative|Ankle Fractures|Ankle Injuries and Disorders
Interventions: DRUG: Exparel|DRUG: Peripheral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses
Status: UNKNOWN
Conditions: Bowel Obstruction|Bowel Ischemia|Diverticulitis|Abnormality of the Gastrointestinal Tract|Symptomatic Disorders of the Gastrointestinal Tract|Stoma Ileostomy|Cancer of the Gastrointestinal Tract|Crohn Disease|Ulcerative Colitis|Familial Adenomatous Polyposis|Pancreatic Neoplasms|Hepatobiliary Neoplasm
Interventions: DIAGNOSTIC_TEST: ICG-NIRF Imaging plus ingress and egress analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Perfusion Outcomes With Near Infrared-Indocyanine Green Imaging System in Laparoscopic Total Mesorectal Excision for Mid- or Low-rectal CanceR
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: application of near infrared-indocyanine green imaging system|PROCEDURE: Non-application of near infrared-indocyanine green imaging system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CommunityRx-Dementia
Status: COMPLETED
Conditions: Health Related Social Needs (HRSN)
Interventions: BEHAVIORAL: Community Rx-Dementia "CRxD" Caregiver Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Evaluation of Cultured Milk Drink on Immune Status of Patients With Irritable Bowel Syndrome: Constipation Predominant
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation
Interventions: DIETARY_SUPPLEMENT: Cultured milk drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of ELLIPTA Dry Powder Inhaler (DPI) Versus DISKUS DPI Used With HandiHaler DPI in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: ELLIPTA placebo DPI|DEVICE: DISKUS placebo DPI|DEVICE: HandiHaler placebo DPI|OTHER: Inhaler preference questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: cisplatin|DRUG: temozolomide|GENETIC: fluorescence in situ hybridization|GENETIC: loss of heterozygosity analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niacin As Secondary Prevention Of Coronary Artery Disease (NASPOCAD)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Niacin|DRUG: Niacin+Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,S
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: BIOLOGICAL: FMP1/AS02|BIOLOGICAL: RTS,S/AS02|OTHER: AS02 adjuvant alone|OTHER: Malaria challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: azelastine hydrochloride 0.15% Nasal Spray|DRUG: azelastine hydrochloride 0.15% and Placebo|DRUG: Azelastine 0.1%, Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects
Status: COMPLETED
Conditions: Drug-drug Interaction
Interventions: DRUG: Omeprazole 40 MG|DRUG: Famotidine 40 mg|DRUG: Telotristat ethyl 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Infraclavicular Nerve Blocks: Needle Versus Catheter Local Anesthetic Bolus
Status: WITHDRAWN
Conditions: Nerve Block
Interventions: PROCEDURE: Local Anesthetic given via perineural catheter for infraclavicular nerve block.|PROCEDURE: Local Anesthetic given via needle for infraclavicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Randomized, Placebo-controlled, Double-blind Study of EG017 in Female Patients With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: EG017 3mg|DRUG: EG017 6mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With Mitomycin c/5-FU/FA in Pretreated Gastrointestinal Cancer Patients With Metastases (>= Second-line Treatment)
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Mitomycin C|DRUG: 5-FU|DRUG: Folinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Cognitive Training in Alcohol Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Function|Feasibility
Interventions: BEHAVIORAL: Cognitive training using the Systemic Lisbon Battery|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of Trivalent Coronavirus Vaccine Candidate VBI-2901e With E6020 Adjuvant
Status: WITHDRAWN
Conditions: COVID-19|Coronavirus Infections
Interventions: BIOLOGICAL: VBI-2901e
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Two Electronic Gloves in the Measurement of Joint Movement in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: Data gloves to perform movements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapeutic Agent Toxicity|Fatigue|Neuropathy|Neurotoxicity
Interventions: DIETARY_SUPPLEMENT: acetyl-L-carnitine hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Defining the Optimal Hormonal Replacement Therapy in Turner Syndrome
Status: COMPLETED
Conditions: Turner Syndrome
Interventions: DRUG: estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reclassifying Constipation Using Imaging and Manometry
Status: UNKNOWN
Conditions: Constipation - Functional|Irritable Bowel Syndrome Characterized by Constipation
Interventions: PROCEDURE: MRI Motility|PROCEDURE: High Resolution Manometry|DRUG: Bisacodyl|DRUG: Hyoscine butylbromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study on TIL for the Treatment of Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Tumor Infiltrating Lymphocytes|Treatment Side Effects|Effects of Immunotherapy
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Validation of a Plasma Transfusion Dosing Algorithm in Patients With Chronic Liver Disease
Status: COMPLETED
Conditions: Liver Disease
Interventions: BIOLOGICAL: Fresh Frozen Plasma|DIAGNOSTIC_TEST: Pre-Transfusion International Normalized Ratio (INR)|DIAGNOSTIC_TEST: Post-Transfusion International Normalized Ratio (INR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Flexibly Dosed BMS-820836 in the Treatment of Patients With Treatment Resistant Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Duloxetine|DRUG: Placebo matching with BMS-820836|DRUG: BMS-820836|DRUG: Duloxetine|DRUG: Placebo matching with Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)
Interventions: DRUG: Bedaquiline|DRUG: Clarithromycin|DRUG: Ethambutol|DRUG: Rifampicin|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrical Stimulation on Individuals With Chronic Stroke in Patients With Chronic Stroke
Status: UNKNOWN
Conditions: Chronic Stroke
Interventions: DEVICE: Active Electrical stimulation|DEVICE: Sham Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginoscopy Against Standard Treatment (VAST): a Randomised Controlled Trial
Status: COMPLETED
Conditions: Hysteroscopy Technique
Interventions: PROCEDURE: Vaginoscopy|PROCEDURE: Standard Hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men
Status: COMPLETED
Conditions: HIV|Gonorrhea|Chlamydia
Interventions: BEHAVIORAL: Keep It Up!|BEHAVIORAL: HIV Knowledge Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Risk Factors for Bowel Dysfunction at Preschool and Early Childhood Age in Children With Hirschsprung Disease
Status: RECRUITING
Conditions: Bowel Dysfunction|Hirschsprung Disease|Risk Factor|Incontinence|Constipation
Interventions: OTHER: bowel function score(BFS) questionnaire survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arthroscopic Primary Repair of the Anterior Cruciate Ligament (ACL)
Status: COMPLETED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: PROCEDURE: Arthroscopic ACL Primary Repair|PROCEDURE: Arthroscopic ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Clonidine to Improve Leg Weakness in People With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Clonidine Patch|OTHER: Matching Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Core Stability Training on Trunk Control in Patients With Post-hemorrhagic Stroke
Status: SUSPENDED
Conditions: Hemorrhagic Stroke
Interventions: OTHER: Interventional programme|OTHER: General exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Develop and Evaluate the Effectiveness of a Self-Care Smartphone Application on the Self-Efficacy, and Resilience Among Newly Diagnosed Breast Cancer Patients Undergoing Treatment
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasm|Breast Malignant Tumor|Resilience|Self-efficacy
Interventions: DEVICE: The Breast Cancer Self-Care App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Open Label Trial of PEG-IFN, RBV & TVR vs. PEG-IFN & RBV Alone in Tx of HCV-1 in HIV-1 Co-infected Patients (CHAT)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Ribavirin|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Is Insulin Resistance and/or Glucose Intolerance Pathogenetic in the Development of a Reduced Incretin Effect
Status: COMPLETED
Conditions: Insulin Resistance|Glucose Intolerance
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Sumatriptan|DRUG: PF-06651600
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia
Status: UNKNOWN
Conditions: Oral Leukoplakia
Interventions: DIETARY_SUPPLEMENT: topical melatonin|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Metabolic Changes in Response to Glucagon Infusion
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Total Pancreatectomy|Diabetes Mellitus
Interventions: DRUG: Glucagon|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Aripiprazole (LAI) on Phychosocial/Cognitive Functioning, pt Reported AcceptabilityofTreatment in Sch
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole 400mg LAI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ankle Instability Using Foot Intensive Rehabilitation
Status: RECRUITING
Conditions: Ankle Injuries|Ankle Sprains
Interventions: BEHAVIORAL: Standard of Care Rehabilitation (SOC)|BEHAVIORAL: Foot Intensive Rehabilitation (FIRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Multicenter, 2-Dose Level. Open-Label, Phase IIa Study With the Intraperitoneally Infused Trifunctional Bispecific Antibody Removab(TM) (Anti-EpCAM x Anti-CD3) to Select the Better Dose Level in Platinum Refractory Epithelial Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: BIOLOGICAL: anti-EpCAM x anti-CD3 (removab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Intervention Based on Implicit Theories of Personality on the Prevention of Adolescent Dating Violence
Status: COMPLETED
Conditions: Dating Violence
Interventions: BEHAVIORAL: Incremental theory of personality|OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Oral LOXO-338 in Patients With Advanced Blood Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, B-cell Marginal Zone|Lymphoma, Non-Hodgkin|Multiple Myeloma|B-cell Lymphoma|Waldenstrom Macroglobulinemia|Lymphoma, Mantle-Cell
Interventions: DRUG: LOXO-338|DRUG: Pirtobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of STBF Photodynamic Therapy for Moderate and Severe Acne Vulgaris
Status: UNKNOWN
Conditions: Acne
Interventions: PROCEDURE: Shengtaibufen Photodynamic Therapy(STBF-PDT)|PROCEDURE: Red light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence to StrategiCally Enhance Pulmonary Embolism Response Team Activation
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism Subacute Massive
Interventions: DIAGNOSTIC_TEST: Walking test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of IV and Oral Esomeprazole in Prevention of Recurrent Bleeding From Peptic Ulcers After Endoscopic Therapy
Status: COMPLETED
Conditions: Peptic Ulcer|Bleeding
Interventions: DRUG: Oral esomeprazole|DRUG: Intravenous Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab for the Inhibition of Neovascularization in the Cornea Following Corneal Transplant Surgery
Status: COMPLETED
Conditions: Corneal Neovascularization
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment" (PROTECT-HF)
Status: RECRUITING
Conditions: Bradycardia|Pacing|Right Ventricular Pacing|His Bundle Pacing|Left Bundle Branch Area Pacing
Interventions: DEVICE: Pacemaker - Physiological pacing|DEVICE: Pacemaker - Right Ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Colesevelam|DRUG: Colesevelam matching placebo|DRUG: Insulin glargine (Lantus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of LM-102 in Patients With Advance Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: LM-102 Injection|COMBINATION_PRODUCT: LM-102 Injection combined with SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety
Status: COMPLETED
Conditions: Major Depression With Comorbid Anxiety Symptoms
Interventions: DRUG: Quetiapine Fumarate (Seroquel®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Refinement of Suicide Risk Management Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Structured Interview|Narrative Assessment|Safety Plan|Crisis Response Plan
Interventions: BEHAVIORAL: Safety Plan|BEHAVIORAL: Crisis Response Plan|BEHAVIORAL: Structured interview|BEHAVIORAL: Narrative Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acceptance and Commitment Therapy for Problematic Chemsex
Status: RECRUITING
Conditions: Hypersexuality|Compulsive Sexual Behavior|Sexualized Drug Use (Chemsex)
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: caspofungin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gastric Cancer Sentinel Lymph Node Mapping
Status: UNKNOWN
Conditions: Gastric Cancer|Sentinel Lymph Node|Early Gastric Cancer
Interventions: PROCEDURE: Sentinel Lymph Node Sampling|DRUG: Radioactive Tracers|DRUG: Methylene Blue 20 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fibroscan Study in HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Confirmed Diagnosis of Hepatocellular Carcinoma|Patients Who Are Scheduled to Undergo Transarterial Chemobolization, Systemic Therapy Surgery|Child's A to C Cirrhosis
Interventions: OTHER: Fibroscan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Recombinant Porcine Factor VIII (FVIII) in Hemophilia and Inhibitors to FVIII
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: recombinant porcine coagulation factor VIII (OBI-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast Surgery
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain|Opioid Analgesic Adverse Reaction|Surgery|Postoperative Pain|Breast Disease
Interventions: OTHER: Opioid Analgesia (OA) [Multimodal analgesia including opioid drugs]|OTHER: Opioid-Free Analgesia (OFA) [Multimodal analgesia not including opioid drugs]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 Stage
Status: RECRUITING
Conditions: Mouth Neoplasms|Carcinoma, Squamous Cell
Interventions: DRUG: TPF group|PROCEDURE: surgery group|RADIATION: Post-operative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Accuracy of Different Blood Glucose Monitoring Systems (CGM and FGM)
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DEVICE: CGM|DEVICE: FGM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Dementia, Vascular
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pentavalent DTaP-Hep B-IPV
Status: COMPLETED
Conditions: Diphtheria|Hepatitis B|Poliomyelitis|Pertussis|Tetanus
Interventions: BIOLOGICAL: DTaP-Hep B-IPV Vaccine|BIOLOGICAL: Monovalent Hep B Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant plus Ondansetron|DRUG: Ondansetron plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: 18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 18F-fluciclovine PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation
Status: NOT_YET_RECRUITING
Conditions: Respiratory Failure
Interventions: OTHER: Sevoflurane vaporized in ECMO machines
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Islet Cell Transplant for Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Allogenic Human Islet Cells|DRUG: Immunosuppressive Agents|DRUG: Gastrin 17
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Human Dose Trial for a New Medication to Potentially Treat Liver Diseases
Status: RECRUITING
Conditions: Healthy Volunteers|Hepatic Steatosis
Interventions: DRUG: NNC0581-0001|DRUG: Placebo (NNC0581-0001)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Theta Burst Stimulation on Modulation of Mirror Illusion-induced Rhythm Suppression in Stroke
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: DEVICE: Intermittent theta burst stimulation|BEHAVIORAL: Mirror Therapy|DEVICE: Sham intermittent theta burst stimulation|BEHAVIORAL: Sham mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular Treatment
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Butylphthalide|DRUG: Butylphthalide Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence
Status: TERMINATED
Conditions: Melanoma|Melanoma Stage III|Melanoma Stage IV|Melanoma (Skin)
Interventions: BIOLOGICAL: Bempegaldesleukin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques
Status: TERMINATED
Conditions: Tibial Fractures
Interventions: OTHER: 3D printed plastic model prototype|OTHER: 3D CT scan|OTHER: Plain film radiographs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I-II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 in Advanced Solid Malignancies, and Efficacy in HER2+ or ER+ Locally Advanced or Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Hematologic Neoplasms
Interventions: DRUG: AUY922 2 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation With Attention Bias Modification Training for Binge Eating Disorder
Status: UNKNOWN
Conditions: Binge-Eating Disorder
Interventions: OTHER: Simultaneous Attention Bias Modification Training and Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With Myelofibrosis
Status: COMPLETED
Conditions: Anemia|Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: DRUG: ruxolitinib phosphate|DRUG: danazol|OTHER: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI0639 in Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: MEDI0639
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endostar First-line Treatment of Advanced NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Endostar|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain|Mild Cognitive Impairment|Older Adults|Physical Activity
Interventions: BEHAVIORAL: Active Brains 1|BEHAVIORAL: Active Brains 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral and Dental Tolerance and Efficacy on Dentinal Hypersensitivity of a Dental Gel, on Adults
Status: UNKNOWN
Conditions: Dentinal Hypersensitivity
Interventions: DEVICE: V063B-DP3003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices.
Status: COMPLETED
Conditions: Cirrhosis With Esophageal Varices
Interventions: DRUG: Carvedilol|DRUG: Carvedilol + Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus|Pre-diabetes|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Shared decision-making for diabetes prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nonablative Fractional Diode Laser for Treatment of Skin Resurfacing and Pigmented Lesions
Status: COMPLETED
Conditions: Skin Texture|Pigmented Lesions
Interventions: DEVICE: Nonablative Fractional Diode Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma|Hypopharyngeal Squamous Cell Carcinoma|Laryngeal Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma|Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage III Hypopharyngeal Carcinoma AJCC v8|Stage III Laryngeal Cancer AJCC v8|Stage III Lip and Oral Cavity Cancer AJCC v8|Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8|Stage IV Hypopharyngeal Carcinoma AJCC v8|Stage IV Laryngeal Cancer AJCC v8|Stage IV Lip and Oral Cavity Cancer AJCC v8|Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|PROCEDURE: Chest Radiography|DRUG: Cisplatin|PROCEDURE: Computed Tomography|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|DRUG: Xevinapant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)
Status: COMPLETED
Conditions: Insulin Resistance|Impaired Glucose Tolerance|PreDiabetes|Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Fibre supplement (potato-pectin)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: High-protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Anti-CD147 Humanized Meplazumab for Injection to Treat With 2019-nCoV Pneumonia
Status: COMPLETED
Conditions: Coronavirus Disease 2019 (COVID-19)
Interventions: DRUG: Meplazumab for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Digital Flu Intervention for People With Cardiovascular Conditions
Status: COMPLETED
Conditions: Cardiovascular Diseases|Atrial Fibrillation|Abnormal Heart Rhythms|Cardiac Arrest|Heart Attack|Myocardial Infarction|Coronary Heart Disease|Heart Failure|Stroke|Cerebrovascular Accident
Interventions: OTHER: Targeted digital intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.
Status: RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: GENETIC: genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"
Status: RECRUITING
Conditions: Thrombotic Microangiopathy|Acute Kidney Injury|Hemolytic Uremic Syndrome|Nephrology|Kidney Diseases
Interventions: OTHER: Collecting datas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants
Status: TERMINATED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: inhaled nitric oxide|DRUG: Placebo Comparator - nitrogen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone
Status: UNKNOWN
Conditions: Acute Disseminated Encephalomyelitis|Devic's Syndrome|Marburg's Variant of Multiple Sclerosis|Balo's Concentric Sclerosis|Acute Transverse Myelitis
Interventions: PROCEDURE: Plasma exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of Activated Recombinant Human Factor VII for Preventing Early Hematoma Growth in Acute Intracerebral Haemorrhage
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Intracerebral Haemorrhage
Interventions: DRUG: activated recombinant human factor VII|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of PRO283698 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: placebo|DRUG: PRO283698
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Subdural Hematoma|Traumatic Brain Injury|Ischemic Stroke|Fever|Intracerebral Hemorrhage
Interventions: DRUG: Bromocriptine 5 MG|DRUG: Acetaminophen 650 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis
Status: COMPLETED
Conditions: Gastroenteritis|Dehydration
Interventions: DRUG: Standard IV rehydration|DRUG: Rapid intravenous rehydration (RIVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer|Colorectal Cancer
Interventions: DRUG: MORAb-004|DRUG: Placebo|OTHER: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: PL-3994 Aqueous Intravenous Solution Dose Ascention|DRUG: PL-3994 Aqueous Intravenous Solution Single Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERAS Protocol for Single-level Posterior Lumbar Arthrodesisprospective Study.
Status: UNKNOWN
Conditions: Mobility|Opioid Use|Instable Spine
Interventions: OTHER: Multimodal, multidisciplinary approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Hydroxypropyl Guar Galactomannan|DRUG: 0.1% sodium hyaluronate ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone and insulin|DRUG: Pioglitazone and metformin and insulin|DRUG: Metformin and insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplantation in Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: PROCEDURE: Autologous stem cell transplantation|PROCEDURE: DHAP rescue and Autologous stem cell transplantation|PROCEDURE: DHAP rescue and F+C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEFA (Non Esterified Fatty Acid) , Adipose Factors Behind Insulin Sensitivity
Status: COMPLETED
Conditions: Obesity|Non-obese Controls
Interventions: OTHER: Obese|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Aiming at Assessing the Effect of Humidification on the Comfort of the Patient Receiving an Oxygen Therapy
Status: COMPLETED
Conditions: Oxygen Inhalation Therapy
Interventions: PROCEDURE: Humidification|PROCEDURE: No Humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of the Herbal Medicine Sominex ® (Passiflora Incarnata L., Valeriana Officinalis L. and Crataegus Oxyacantha L.), Manufactured by the Laboratory EMS S / A in Patients With Psychophysiological Insomnia
Status: UNKNOWN
Conditions: Insomnia
Interventions: DRUG: Sominex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Delivering Church-based Interventions to Reduce Stigma and Mental Health Treatment Disparities Among Latinos
Status: ACTIVE_NOT_RECRUITING
Conditions: Help-Seeking Behavior|Stigma, Social
Interventions: BEHAVIORAL: NAMI Mental Health 101 and NAMI FaithNet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS Patients
Status: COMPLETED
Conditions: HIV Infections|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Cidofovir|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nutritional Study to Determine the Effect of Fish Oil on Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: LC-MUFA oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants
Status: COMPLETED
Conditions: Apnea of Prematurity|Preterm Birth|Patent Ductus Arteriosus|Hypoxia, Brain|Cardiac Output, Low|Bradycardia Neonatal|Hypoxia Neonatal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glycaemic, Insulinaemic and Appetite Responses to Two Different Types of Porridge
Status: COMPLETED
Conditions: Postprandial Glycaemia,|Postprandial Insulinaemia|Appetite
Interventions: DRUG: Test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Candin for the Treatment of Common Warts
Status: RECRUITING
Conditions: Common Warts (Verruca Vulgaris)
Interventions: DRUG: Candin, Intradermal Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerve Versus Neurostimulation
Status: COMPLETED
Conditions: Thyroidectomy
Interventions: PROCEDURE: thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer
Status: UNKNOWN
Conditions: Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Serous Adenocarcinoma|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: OTHER: Clinical Observation|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Paclitaxel Poliglumex|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT