pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 "Long Haul" Pulmonary Compromise
Status: WITHDRAWN
Conditions: Covid19
Interventions: BIOLOGICAL: COVI-MSC|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Revascularization in Stable Ischemic Heart Disease Using P.E.T. Imaging
Status: TERMINATED
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: Revascularization by Coronary Artery Bypass Graft or Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux
Status: COMPLETED
Conditions: GERD
Interventions: BEHAVIORAL: Diaphragmatic Breathing|BEHAVIORAL: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Schizophrenia Treatment With Photoneuromodulation
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: Photoneuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Levels of CAZ-AVI and Metronidazole in the Blood When Given Together and Separately
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CAZ-AVI|DRUG: metronidazole|DRUG: CAZ-AVI + metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK3923868|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19
Status: COMPLETED
Conditions: COVID|COVID-19|SARS-CoV 2|Coronavirus|Corona Virus Infection
Interventions: DRUG: Chloroquine|DRUG: Hydroxychloroquine|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ART and Hall Technique for Management of Occlusal-proximal Caries in Primary Molars
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Atraumatic Restorative Treatment|PROCEDURE: Hall Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial on Pre-peritoneal Drainage After Totally Extra-peritoneal Hernioplasty for Inguinal Hernia
Status: UNKNOWN
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: preperitoneal suction drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patellar Tendon Regeneration With Platelet-rich Plasma
Status: COMPLETED
Conditions: Knee Instability
Interventions: PROCEDURE: Platelet-rich plasma|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole
Status: TERMINATED
Conditions: Gastric Acid
Interventions: DRUG: Esomeprazole first|DRUG: Generic omeprazole first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: HYQVIA|BIOLOGICAL: KIOVIG|BIOLOGICAL: Cuvitru
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC278-TiDP6-C154: Evaluation of the Possible Influence of Omeprazole Intake - and the pH Increase in the Stomach Triggered by Omeprazole Intake - on the Blood Levels of TMC278 in Healthy Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: TMC278; Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: αβT Cell/CD19+ B Cell Depletion for Alternative Donor Allogeneic Hematopoietic Cell Transplantation (HSCT)
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Hematologic Malignancy
Interventions: DEVICE: CliniMACS®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MBSR on Physiological and Psychological Factors in Patients With HF
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: The experimental group used App for MBSR intervention|OTHER: the "Heart Care Life" app|OTHER: Phone interview once a week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Mindfulness-based Intervention on Epigenetic Mechanisms, Cognition Function, Stress Response, and Well-being
Status: COMPLETED
Conditions: Mindfulness|DNA Methylation|Learning and Memory|Stress|Psychological Well-being
Interventions: OTHER: Mindfulness meditation training|OTHER: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Quilizumab Versus Placebo in Patients With Refractory Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: Placebo|DRUG: Quilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-DTBZ for l Diagnosis of Parkinson's Disease and Monitoring the Severity of Disease by VMAT2 PET Imaging
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: 18F-DTBZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Taxotere®, Followed by Myocet® and Cyclophosphamide First Line Treatment in HER2 Neg Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel, Liposomal doxorubicine and Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: OTHER: Therapy for Targeted Therapy-related Fatigue (TTF)|OTHER: Wait-List Control Condition (WLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: OTHER: High end-tidal CO2|OTHER: Low CO2 group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dosing of Overground Robotic Gait Training With Functional Outcomes and Neuroplasticity After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Robotic Gait Training|OTHER: Usual Care (UC) Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Energy Intake by Implementing Recommended Food Texture Through Dietary Guidance
Status: COMPLETED
Conditions: Energy Intake|Activities of Daily Living|Quality of Life|Protein Intake|Fluid Balance|Lean Body Mass|Fat Mass|Weight
Interventions: OTHER: Dietary guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Molecular Weight Heparin in Recurrent Miscarriage With Negative Antiphospholipid Antibodies
Status: COMPLETED
Conditions: Recurrent Miscarriage
Interventions: DRUG: LMWH+Folic acid|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of a Dengue Virus DNA Vaccine
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: D1ME100 (dengue-1 premembrane/envelope DNA vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Inoperable Locally Advanced Breast Cancer|Metastatic Breast Cancer (MBC)
Interventions: DRUG: BEZ235|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participants
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Vanzacaftor|DRUG: Vanzacaftor Placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lipidic Nutrients on Memory and Well Being in Healthy Aging Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin A +Long chain PUFA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Intermittent and Continuous Enteral Feeding on Ventilator-associated Pneumonia in Pediatric ICUs
Status: UNKNOWN
Conditions: Enteral Feeding|Ventilator-Associated Pneumonia
Interventions: OTHER: Intermittent enteral feeding|OTHER: Continuous enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: Flortaucipir F18|PROCEDURE: Brain PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD
Status: NOT_YET_RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Surufatinib 250mg/d qd once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Term Effects of Connective Tissue Massage After Hysterectomy
Status: COMPLETED
Conditions: Massage|Hysterectomy|Pain
Interventions: OTHER: Massage and patient education|BEHAVIORAL: Routine care and advising
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Feasibility/Pilot Study With [123I]-IBZM SPECT (DOPA-SYN)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: carbidopa/l-dopa|DRUG: carbidopa/l-dopa/entacapone|DRUG: Stalevo|PROCEDURE: [123I]-IBZM imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction
Status: RECRUITING
Conditions: Dry Eye
Interventions: DEVICE: taVNS|DRUG: Hyaluronic acid eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory, Observational, Non-interventional, Open Label, Remote Pilot Study to Assess Adherence in COPD Subjects
Status: COMPLETED
Conditions: Moderate Chronic Obstructive Pulmonary Disease|Severe Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Adherence to wearing a Spire wearable health monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing the Feasibility and Effectiveness of Introducing Pulse Oximetry in IMCI Services
Status: UNKNOWN
Conditions: Childhood Pneumonia|Hypoxemia
Interventions: DEVICE: Pulse Oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER)
Status: TERMINATED
Conditions: Pediatric Perioperative Blood Pressure Management
Interventions: DRUG: clevidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six Week Topical Cream Study for Subjects With Ichthyosis Vulgaris
Status: COMPLETED
Conditions: Ichthyosis Vulgaris
Interventions: DRUG: 146-9251 cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention Study on Food Based Dietary Guidelines for Sustainable and Healthy Lifestyles
Status: COMPLETED
Conditions: Dietary Habits|Healthy Diet|Healthy Nutrition|Personalized Nutrition
Interventions: BEHAVIORAL: Healthy climate-friendly dietary guidelines|BEHAVIORAL: Healthy dietary guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Enalapril Plus Folic Acid on Blood Pressure and Glycometabolism
Status: COMPLETED
Conditions: Plasma Total Homocysteine Level|Blood Pressure
Interventions: DRUG: enalapril plus folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Customized Bioprinting Technology for Practical Regeneration of the Respiratory Tract (Trachea)
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: PROCEDURE: Three-dimensional patient-specific bioprinting trachea implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Contrast Enhanced Mammography to Breast MRI in Screening Patients at Increased Risk for Breast Cancer
Status: COMPLETED
Conditions: Women at Increased Risk for Developing Breast Carcinoma
Interventions: OTHER: Mammography (CESM) and MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of tDCS on the Neuronal Mechanisms of Cognitive Control in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary Dysplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: Allogeneic Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep
Status: RECRUITING
Conditions: Circadian System
Interventions: OTHER: LE protocol 1: exposure to artificial light|OTHER: LE protocol 2: natural daylight|OTHER: LE protocol 3: natural daylight with reduced short-wavelength proportions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients
Status: COMPLETED
Conditions: Tethered Spinal Cord|Brain Tumor|Cranio Cervical Compression
Interventions: OTHER: Isoflurane, Propofol, Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Stealth Liposomal Doxorubicin HCl ( DOX-SL ) in the Treatment of Moderate to Severe AIDS-Related Kaposi's Sarcoma.
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Doxorubicin hydrochloride (liposomal)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laser in Treatment of Vulval Warts
Status: UNKNOWN
Conditions: Vulval Wart
Interventions: DEVICE: nd yag laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA)
Status: COMPLETED
Conditions: Familial Hemiplegic Migraine|Migraine With Aura|Healthy
Interventions: DRUG: CGRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Additive Effect of Intravenous Acetaminophen on Postoperative Pain Control
Status: COMPLETED
Conditions: Postoperative Pain|Gynecologic Disease
Interventions: DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Functions in MTBI Patients With Headache by rTMS
Status: COMPLETED
Conditions: TBI (Traumatic Brain Injury)
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing the Uptake of Advanced Directives in SingHealth Polyclinics
Status: COMPLETED
Conditions: Advanced Medical Directive, a Legal Document Signed in Advance to State Healthcare Preferences
Interventions: BEHAVIORAL: standardised face-to-face counselling session|BEHAVIORAL: advanced medical directive pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Different Aerobic Exercise Programs With Nutritional Interventions in Hypertensive and Overweight People
Status: COMPLETED
Conditions: Hypertension|Overweight|Sedentary
Interventions: BEHAVIORAL: DIET|BEHAVIORAL: DIET & MODERATE CONTINUOUS TRAINING|BEHAVIORAL: DIET & HIGH VOLUME HIIT|BEHAVIORAL: DIET & LOW VOLUME HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function
Status: UNKNOWN
Conditions: Adult Polycystic Kidney Disease|Kidney Neoplasms|Kidney Dysfunction
Interventions: DIAGNOSTIC_TEST: sinistrin clearance dynamic measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy
Status: UNKNOWN
Conditions: Pain|Nerve Block
Interventions: DRUG: nerve block with 0.5% ropivacaine|OTHER: without any nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Safety and Immunogenicity of Recombinant SARS-CoV-2 S-Trimer Vaccine (CHO Cells) as Booster Vaccination in Populations Aged 18 to 59 Years
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: the recombinant SARS-CoV-2 S-Trimer vaccine/inactivated SARS-CoV-2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Small Cell Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma|Stage III Cervical Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pegfilgrastim|DRUG: Topotecan Hydrochloride|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress and Musculoskeletal Health in Employees
Status: RECRUITING
Conditions: Musculoskeletal Diseases or Conditions|Musculoskeletal Pain|Musculoskeletal Health|Stress|Work Related Stress|Occupation-related Stress Disorder|Medically Unexplained Symptoms
Interventions: OTHER: Diaphragmatic breathing (DF)|OTHER: Progressive Muscle Relaxation (PMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Topotecan and Bevacizumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Did Not Respond to Previous Systemic Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Fentanyl or Local Anesthetic Infiltration for Pain Reducing During Spinal Needle Insertion
Status: COMPLETED
Conditions: Anesthesia|Spinal Puncture
Interventions: PROCEDURE: Comparison of intravenous fentanyl and local anesthetic infiltration in pain reducing during spinal needle puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug
Status: TERMINATED
Conditions: Asthma|Allergy|Allergic Rhinitis|Rhinitis, Allergic, Seasonal
Interventions: DRUG: Amb a 1-immunostimulatory oligodeoxyribonucleotide conjugate (AIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Incontinence Associated Dermatitis in Older Children and Adults
Status: COMPLETED
Conditions: Incontinence Associated Dermatitis
Interventions: DRUG: Skin care regimen with Calmoseptine ointment|DRUG: Skin care regimen with Destin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age
Status: COMPLETED
Conditions: Endocrine Disrupting Chemicals|Environmental Exposure|Health Literacy|Bisphenol A|Phthalate Exposure|Survey
Interventions: DIAGNOSTIC_TEST: Mail-in Urine Test for EDCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinoma
Status: RECRUITING
Conditions: Basal Cell Carcinoma|Basal Cell Carcinoma of Skin, Site Unspecified|Skin Cancer|Invasive Carcinoma
Interventions: DRUG: Sonidegib|DRUG: Imiquimod|PROCEDURE: Surgery|OTHER: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIND Diet to Improve Cognitive Function in Mild Stroke Patients (MINDICOMS) II
Status: RECRUITING
Conditions: Dementia|Stroke|Cognitive Change|Cerebrovascular; Disorder, Thrombotic
Interventions: BEHAVIORAL: General dietary advice|BEHAVIORAL: Localized MIND diet intervention|OTHER: Routine medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Non-metastatic Prostate Cancer|Prostate Adenocarcinoma
Interventions: PROCEDURE: Radical therapy (radiotherapy or prostatectomy [radiotherapy can be external beam or brachytherapy]|PROCEDURE: Focal therapy|PROCEDURE: Focal therapy after Finasteride 5Mg tablets for 12 weeks|PROCEDURE: Focal therapy after Bicalutamide 50Mg tablets for 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Forearm and Upper Arm Combi Cast for Distal Forearm Fractures in Children
Status: COMPLETED
Conditions: Salter-Harris Type I|Salter-Harris Type 2|Radius Fractures|Forearm Fracture
Interventions: DEVICE: combi cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of an Epstein-Barr Virus (EBV) gp350-Ferritin Nanoparticle Vaccine in Healthy Adults With or Without EBV Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: EBV|Epstein-Barr Virus Infection|Infectious Mononucleosis
Interventions: BIOLOGICAL: EBV gp350-Ferritin Vaccine|OTHER: Matrix-M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RADICALS - Radiotherapy and Androgen Deprivation In Combination After Local Surgery
Status: COMPLETED
Conditions: Gastrointestinal Complications|Prostate Cancer|Sexual Dysfunction|Urinary Complications
Interventions: DRUG: bicalutamide|DRUG: goserelin acetate|DRUG: leuprolide acetate|PROCEDURE: adjuvant therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma
Status: NOT_YET_RECRUITING
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Dinutuximab beta|DRUG: chemotherapy treatment called GPOH|DRUG: chemotherapy treatment called rapid COJEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound and Respiratory Physiological Signals in Lung Diseases
Status: RECRUITING
Conditions: Interstitial Lung Disease|Interstitial Lung Diseases|Interstitial Pneumonia|Chronic Obstructive Pulmonary Disease|Emphysema or COPD|Ultrasonography|Ultrasound Imaging|Ultrasound
Interventions: DIAGNOSTIC_TEST: Lung ultrasound, computed tomographic scan and patch-based cardio-respiratory evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spinal Stenosis|Lumbar Spondylolisthesis|Low Back Pain|Sciatica|Neurogenic Claudication
Interventions: DRUG: Herbal medicine|PROCEDURE: Chuna manual medicine|PROCEDURE: Bee venom pharmacopuncture|PROCEDURE: Pharmacopuncture|PROCEDURE: Acupuncture|PROCEDURE: Electroacupuncture|PROCEDURE: Cupping|PROCEDURE: Other intervention(s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Zoster Vaccine (ZOSTAVAX™) Made With an Alternative Manufacturing Process (AMP) (V211-042 AM1)
Status: COMPLETED
Conditions: Herpes Zoster|Shingles
Interventions: BIOLOGICAL: Zoster Vaccine, Live (AMP)|BIOLOGICAL: Zoster Vaccine, Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Training Given to Women With Obesity Patients According to the Health Belief Model
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Obesity Training Based on Health Belief Model|OTHER: Post-training follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks
Status: COMPLETED
Conditions: Port Wine Stain
Interventions: DRUG: Imiquimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAP Block in Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine +magnesium sulphate|DRUG: Bupivacaine only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine and Morphine Versus Morphine Alone for the Treatment of Acute Pain in the Emergency Department
Status: TERMINATED
Conditions: Acute Pain
Interventions: DRUG: Ketamine|DRUG: Morphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess CH1504 in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CH-1504|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
Status: COMPLETED
Conditions: Atopic Dermatitis|Ichthyosis|Psoriasis
Interventions: OTHER: Itch Questionnaire and Interview|OTHER: Stigma Questionnaire and Interview|OTHER: Cognitive Interview and PROMIS Itch Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating the Effectiveness of Within Versus Across-Category Front-of-Package Lower-Calorie Labelling on Food Demand
Status: COMPLETED
Conditions: Food Selection
Interventions: BEHAVIORAL: Front-of-pack labeling strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Transcutaneous Vagus Nerve Stimulation on Cognitive Function
Status: COMPLETED
Conditions: Cognitive Function
Interventions: DEVICE: Transcutaneous vagal nerve stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Online Counseling to Enable Lifestyle-focused Obesity Treatment in Primary Care
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: VLM-S|BEHAVIORAL: VLM-M|BEHAVIORAL: OGR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)
Status: COMPLETED
Conditions: X-Linked Retinitis Pigmentosa
Interventions: GENETIC: AAV2/5-RPGR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Remimazolam Compared With Midazolam During Bronchoscopy:Randomised Controlled Trial
Status: COMPLETED
Conditions: Bronchoscopy|Remimazolam
Interventions: DRUG: Byfavo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Vesatolimod in Antiretroviral Treated Human Immunodeficiency Virus (HIV-1) Infected Controllers
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Vesatolimod|DRUG: Placebo|DRUG: ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GAL1704 for Cheek Augmentation and Correction of Midface Contour Deficiencies
Status: COMPLETED
Conditions: Cheek Augmentation
Interventions: DEVICE: GAL1704|DEVICE: Juvederm Voluma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semilunar and Conventional Coronally Positioned Flap for the Treatment Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession|Root Coverage
Interventions: PROCEDURE: semilunar coronally positioned flap|PROCEDURE: coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen for Chronic Pain in Hysterectomy
Status: COMPLETED
Conditions: Abdominal Hysterectomy (& Wertheim)
Interventions: DRUG: Acetaminophen|DRUG: Isotonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Medication Reviews to Polypharmacy Patients
Status: RECRUITING
Conditions: Polypharmacy Patients|Pharmacist Intervention
Interventions: OTHER: Systematic pharmacist intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO
Status: TERMINATED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: suprachoroidal CLS-TA|DRUG: suprachoroidal sham|DRUG: Lucentis or Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Status: TERMINATED
Conditions: Idiopathic Parkinson's Disease|Drug Induced Dyskinesia
Interventions: DRUG: Topiramate|DRUG: Placebo|DRUG: Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Low Back and Lower Extremity Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Lumbar Interlaminar Epidural|PROCEDURE: Lumbar Interlaminar Epidural injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Microembolism After the Intervention Surgery of Intracranial Aneurysms by Administration of Tirofiban
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DRUG: Tirofiban|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Anesthetics on the Change of Alarmins in Lung Cancer Patients Receiving Pulmonary Lobectomy
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Diseases|Carcinoma, Non-Small-Cell Lung|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Respiratory Tract Neoplasms|Carcinoma Bronchiogenic Stage III|Thoracic Neoplasms
Interventions: DRUG: Carboplatin|DRUG: Placlitaxel|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Erlotinib|DRUG: Docetaxel|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canned Herring for Prevention of Childhood Malnutrition During the Early Rainy Season in Rural Guinea-Bissau
Status: COMPLETED
Conditions: Malnutrition|Undernutrition
Interventions: OTHER: Canned Herring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacotherapy of Treatment-Resistant Mania
Status: COMPLETED
Conditions: Mania
Interventions: DRUG: Lithium|DRUG: verapamil|DRUG: verapamil plus lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration
Status: COMPLETED
Conditions: Choledocholithiasis|Gallstone Migration|Cholecystitis|Gallstone Pancreatitis|Cholangitis
Interventions: PROCEDURE: Cholecystectomy with intraoperative cholangiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness and Safety of Mucoadhesive Film Containing A.Oleracea Extract
Status: UNKNOWN
Conditions: Oral Mucosa
Interventions: OTHER: Mucoadhesive film containing Acmella oleracea extract|OTHER: Mucoadhesive film without Acmella oleracea extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Prediabetic State
Interventions: DRUG: Aspirin|DRUG: Alpha lipoic acid|DRUG: Olmesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Levobupivacaine Infiltration on the Post Partum Perineal Pain in Episiotomy, in Primiparous Women After Instrumental Delivery
Status: WITHDRAWN
Conditions: Episiotomy
Interventions: DRUG: Levobupivacaine|OTHER: Physiological serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity
Status: COMPLETED
Conditions: COPD|Emphysema|Lung Diseases
Interventions: BEHAVIORAL: Coaching and Weight Loss for patients with dyspnea|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Different Dietary Fats on Blood Lipids and Metabolic Measures in Healthy Participants
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: OTHER: Coconut oil|OTHER: Butter|OTHER: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Electroacupuncture vs Topical Diclofenac Sodium Gel for Patients With Hand Osteoarthritis
Status: UNKNOWN
Conditions: Hand Osteoarthritis
Interventions: OTHER: Electroacupuncture|DRUG: Topical diclofenac sodium gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ACH-0137171 in Participants With Chronic Hepatitis C Infection
Status: TERMINATED
Conditions: HCV Infection
Interventions: DRUG: ACH-0137171
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Biosimilar Retacrit™ (Epoetin Zeta) in the Treatment of Chemotherapy-Induced Symptomatic Anaemia in Haematology and Oncology
Status: COMPLETED
Conditions: Chemotherapy-induced Symptomatic Anaemia|Solid Tumours|Malignant Lymphomas|Multiple Myeloma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Surgical Proficiency and Effectiveness of the Acumed Scapholunate Repair System in Primary Scapholunate Instability Among Canadians
Status: NOT_YET_RECRUITING
Conditions: Complete Tear of Scapholunate Ligament|Scapholunate Dissociation
Interventions: DEVICE: ACUMED® Scapholunate Repair System Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive Regimens
Status: COMPLETED
Conditions: Comparative Study|Immunosuppressive Agents
Interventions: DRUG: Rapamycin|DRUG: Everolimus|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers Without Charcoal Block
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Fluticasone propionate|DRUG: Salmeterol (as xinafoate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess and Compare the Effects of 5 mg vs. 20 mg Desloratadine on the Development of Cold Urticaria Lesions
Status: COMPLETED
Conditions: Acquired Cold Urticaria
Interventions: DRUG: desloratadine|DRUG: desloratadine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Optimal Stimulation Site for Cervical Dystonia Symptoms: An Exploratory Study
Status: COMPLETED
Conditions: Cervical Dystonia|Spasmodic Torticollis
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol D3|OTHER: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk
Status: UNKNOWN
Conditions: Breast Cancer Female|Inflammation|Postpartum Weight Retention|Diet, Healthy|Risk Reduction
Interventions: BEHAVIORAL: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)
Status: COMPLETED
Conditions: Carcinoma, Merkel Cell
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anorectal Application of 5% Lidocaine Cream Reduces Pain Prior to Periprostatic Nerve Block During Transrectal Ultrasound Guided Biopsy
Status: COMPLETED
Conditions: Pain|Prostate Cancer|Rectal/Anal
Interventions: PROCEDURE: Trans rectal ultrasound guided prostate biopsy|PROCEDURE: Trans rectal ultrasound|PROCEDURE: Prostate biopsy|PROCEDURE: Periprostatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3D Kinematic Assessment of the Human Knee During Physical and Daily Life Activities
Status: NOT_YET_RECRUITING
Conditions: 3D Knee Kinematics
Interventions: DEVICE: 3D knee kinematic assessment under local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC