pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: a Clinical Research of BCMA-Targeted Prime CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Neoplasm, Plasma Cell|Multiple Myeloma in Relapse
Interventions: BIOLOGICAL: BCMA targeted prime CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: HPV Self-Collection|OTHER: Questionnaire Administration|BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Coenzyme Q10 Supplement on Cardiovascular Risk Factors in Subjects at High Risk of Metabolic Syndrome
Status: RECRUITING
Conditions: Metabolic Syndrome|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: coenzyme Q10|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism
Status: TERMINATED
Conditions: REM Behavior Disorder|Parkinsonism
Interventions: DRUG: Rozerem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Comvigen (Bivalent) Vaccine
Status: RECRUITING
Conditions: Safety of a Single Dose of COMVIGEN Vaccine|Reactogenicity of a Single Dose of COMVIGEN Vaccine|Immunogenicity of a Single Dose of COMVIGEN Vaccine|Safety of a Single Dose of BIVALENT Pfizer/BNT Vaccine|Reactogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine|Immunogenicity of a Single Dose of BIVALENT Pfizer/BNT Vaccine
Interventions: BIOLOGICAL: Comvigen (Bivalent, ChulaCov19 BNA159.2)|BIOLOGICAL: BIVALENT Pfizer/BNT vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Free Nonvascularized Fibula Autograft for Tumor-like Lesions in Femoral Neck Using in Pediatric Patients
Status: COMPLETED
Conditions: Bone Diseases
Interventions: PROCEDURE: free nonvascularized fibula autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Toxicity|Neurotoxicity|Drug Toxicity|Adverse Drug Event
Interventions: DRUG: ERIBULIN MESYLATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Two-Part Phase 2a Study of RVX000222 in Patients With End-Stage Renal Disease Treated With Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: Kidney Failure, Chronic
Interventions: DRUG: apabetalone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Ablation Registry
Status: UNKNOWN
Conditions: Atrial Fibrillation (Paroxysmal)|Atrial Fibrillation Recurrent|Atrial Fibrillation Common Gene Variants
Interventions: DEVICE: Extended Electrocardiogram|DEVICE: Body surface potential map
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sham CPAP vs. Straight CPAP for Chronic Cough
Status: COMPLETED
Conditions: Chronic Cough|OSA
Interventions: DEVICE: Straight CPAP|DEVICE: Sham CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TrueRelief Efficacy for Post-cesarean Pain (ELECTRON)
Status: COMPLETED
Conditions: Post-cesarean Pain
Interventions: DEVICE: TrueRelief device|DEVICE: Sham TrueRelief device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ITM vs QL for Pediatric Open Lower Abdominal Procedures
Status: RECRUITING
Conditions: Pain Control|Ureteral Reimplantation|Pediatrics|Intrathecal Morphine
Interventions: DRUG: Intrathecal Morphine|DRUG: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vigabatrin for Treatment of Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: vigabatrin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct Tumours
Status: COMPLETED
Conditions: Bile Duct Cancer
Interventions: DRUG: GEMCIS|DRUG: mFolfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bilateral HF-rTMS on Abstinence in Alcohol Use Disorder Patients With Executive Dysfunction
Status: UNKNOWN
Conditions: Alcohol Withdrawal
Interventions: DEVICE: Active rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aspirin and L-arginine in High Risk Preeclamptic
Status: SUSPENDED
Conditions: High Risk Pregnancy
Interventions: DRUG: L-arginine|DRUG: Placebo (for L-arginine)|DRUG: acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: GIOP Prevention Among People With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Osteoporosis|Rheumatoid Arthritis
Interventions: BEHAVIORAL: Tailored Materials|BEHAVIORAL: Tailored Materials Plus Physician Feedback|BEHAVIORAL: Generic Materials|BEHAVIORAL: No Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Professional Coaching on Early Career Academic Emergency Physicians
Status: COMPLETED
Conditions: Development, Human|Well-Being|Professional Burnout|Goals|Leadership|Professional Role|Physician's Role|Stress|Anxiety
Interventions: BEHAVIORAL: Professional coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Corneal Cross-Linking Comparing Variables
Status: UNKNOWN
Conditions: Unstable Corneas
Interventions: DRUG: Epithelium-On Riboflavin|DRUG: Epithelium-Off Riboflavin|DEVICE: UV Light - Continuous Beam|DEVICE: UV Pulsed Beam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Knee Pain Chronic|Knee Pain Swelling
Interventions: DEVICE: microparticles|PROCEDURE: embolization|PROCEDURE: sham embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock Wave Lithotripsy.
Status: COMPLETED
Conditions: Lithiasis|Nephrolithiasis
Interventions: DIETARY_SUPPLEMENT: Food supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Durvalumab/Anlotinib /Chemotherapy Plus Curative Resection in Stage III Non-Small-Cell Lung Cancer : A Single-arm Phase II Study
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Durvalumab Anlotinib Carboplatin Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Markers of Platelet Activation foR Identification of Late Onset Sepsis in Preterm Infants
Status: RECRUITING
Conditions: Late-Onset Neonatal Sepsis|Necrotising Enterocolitis|Culture Negative Neonatal Sepsis
Interventions: DIAGNOSTIC_TEST: Platelet/Endothelial proteomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: anti-TNF biologics|OTHER: general population|BIOLOGICAL: non-anti-TNF biologics|BIOLOGICAL: ustekinumab|DRUG: systemic non-biological treatments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tamibarotene and Arsenic Trioxide for Relapsed Acute Promyelocytic Leukemia
Status: TERMINATED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Tamibarotene|DRUG: Arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Accuracy of Zygomatico- Maxillary Complex (ZMC) Fractures Reduction Using Patient Specific Guide (PSG) Versus Conventional Technique
Status: UNKNOWN
Conditions: Zygomatic Fractures
Interventions: PROCEDURE: patient specific guide|PROCEDURE: conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Data Analysis of VitalCare Targeted Population Management on Scott and White Chronically Ill Beneficiaries
Status: COMPLETED
Conditions: Chronic Illness
Interventions: BEHAVIORAL: ICC (Integrated Care Coaching) Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ComparIson of Strategies to PrepAre SeveRely CALCified Coronary Lesions 2
Status: RECRUITING
Conditions: Calcified Coronary Artery Disease
Interventions: DEVICE: Super High Pressure Balloon (OPN NC)|DEVICE: Intravascular lithotripsy (IVL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ia Clinical Trial of PCV24 in Children Aged 2-17 Years
Status: NOT_YET_RECRUITING
Conditions: Pneumococcal Infectious Disease
Interventions: BIOLOGICAL: Sinovac PCV24 formulation 1|BIOLOGICAL: Sinovac PCV24 formulation 2|BIOLOGICAL: Prevenar13®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simultaneously Using Traditional Chinese Medicine (Si-Ni-Tang) to Treat Septic Shock Patients
Status: TERMINATED
Conditions: Septic Shock
Interventions: DRUG: Si-Ni-Tang/ Placebo of Si-Ni-Tang
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation Exercise: Effects on Maternal Psychological Health and Delivery Outcomes
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy|Gestational Diabetes|Maternal Psychological Distress
Interventions: OTHER: Telerehabilitation exercise program|OTHER: Routine medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWJ1464 in Patients With Chronic Liver Disease
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Liver Disease
Interventions: DRUG: DWJ1464|DRUG: Placebo of DWJ1464
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: BIOLOGICAL: Imsidolimab|BIOLOGICAL: Placebo Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Therapy Associated With Photobiomodulation on Myelomeningocele
Status: UNKNOWN
Conditions: Physical Therapy Modalities
Interventions: OTHER: physiotherapy exercises|OTHER: PBM|OTHER: SHAM PBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Residual Pulmonary Vascular Obstruction Index Computed With Ventilation/Perfusion SPECT/CT Imaging to Predict the Risk of Venous Thromboembolism Recurrence in Patients With Pulmonary Embolism (PRONOSPECT)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism|Venous Thromboembolism
Interventions: OTHER: Ventilation/Perfusion Single Photon Emission Computed Tomography (V/Q SPECT/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation
Status: COMPLETED
Conditions: Heart Transplantation|Liver Transplantation|Bone Resorption
Interventions: DRUG: Zoledronic acid|DRUG: Alendronate|OTHER: Placebo Zoledronic Acid|OTHER: Placebo Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma
Status: RECRUITING
Conditions: Melanoma Stage Iv|Renal Cell Carcinoma, Metastatic
Interventions: DRUG: IL-2 and Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Telerehabilitation and Supervised Stabilization Exercises in Individuals With Nonspecific Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Supervised Group|OTHER: Telerehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced-dose Radiotherapy for Low-risk Stage III Patients With Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Intensity-modulated radiation therapy|DRUG: Paclitaxel liposome|DRUG: Cisplatin|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exoskeleton Use in Acute Rehab Post Spinal Cord Injury; a Safety and Feasibility Study
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Efficacy and Safety of Guselkumab in Participants With Palmoplantar Pustulosis
Status: COMPLETED
Conditions: Palmoplantar Pustulosis
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplant|Atrial Fibrillation|Atrial Flutter
Interventions: OTHER: HSCT Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization of a Fast-track Concept for Knee Joint Replacement
Status: COMPLETED
Conditions: Knee Arthropathy|Postoperative Pain|Postoperative Complications
Interventions: PROCEDURE: Late local infiltration analgesia|PROCEDURE: Early local infiltration analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Oral Dexamethasone Versus Multi-dose Prednisolone in the Treatment of Acute Exacerbations of Asthma in Children
Status: COMPLETED
Conditions: Asthma|Acute Asthma
Interventions: DRUG: Prednisolone Sodium Phosphate|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Incidence of Gingival Fissures _ a Crossover Single-blinded Randomized Clinical Trial
Status: COMPLETED
Conditions: Gingival Recession|Wounds and Injuries
Interventions: DEVICE: Toothbrush type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open Label Study of Gene Therapy Product (Vesemnogene Lantuparvovec) in Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: vesemnogene lantuparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination
Status: ENROLLING_BY_INVITATION
Conditions: Immunization; Infection|Pregnancy Related|COVID-19
Interventions: BEHAVIORAL: VAX-MOM COVID-19 Intervention|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Immunological Profile of Nickel Dermatitis
Status: COMPLETED
Conditions: Nickel; Eczema|Nickel Sensitivity|Allergy|Inflammatory Response
Interventions: OTHER: Nickel sulfate hexahydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage
Status: COMPLETED
Conditions: Children|Obstructive Uropathy|Acute Renal Failure|Ureteric Stones
Interventions: PROCEDURE: percutaneous nephrostomy insertion|PROCEDURE: bilateral double J ureteric stent|PROCEDURE: Definitive stone management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: COMBINATION_PRODUCT: VCTX210A unit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia
Status: WITHDRAWN
Conditions: HIV-1-infection|ART|Cd4+ Lymphocyte Deficiency|Lymphoid Tissue; Infection|Interleukin
Interventions: BIOLOGICAL: FT538|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Test of Parent-Focused Cannabis-Related Actions and Practices Intervention for Adolescent Marijuana Abuse
Status: COMPLETED
Conditions: Cannabis Use Disorder, Mild|Cannabis Use Disorder, Moderate
Interventions: BEHAVIORAL: Cannabis Actions and Practices Resource for Parents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Impact of Biofeedback on the Inhibitory Control of Healthy Older Adults
Status: COMPLETED
Conditions: Inhibition
Interventions: BEHAVIORAL: Heart rate variability biofeedback; haemoncephalography biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Imaging Study of 89Zr-DFO-HuMab-5B1 With HuMab-5B1
Status: TERMINATED
Conditions: Pancreatic Carcinoma|Tumors That Express CA19-9
Interventions: DRUG: MVT-2163|DRUG: MVT-5873
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Etravirine Administered in Combination With Other Antiretroviral Agents in Antiretroviral Treatment-Experienced HIV-1 Infected Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: Etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Illinois Workplace Wellness Study
Status: UNKNOWN
Conditions: Employee Health and Well-being
Interventions: BEHAVIORAL: Workplace Wellness Program|BEHAVIORAL: Biometric Screening/HRA - No Compensation|BEHAVIORAL: Biometric Screening/HRA - Moderate Compensation|BEHAVIORAL: Biometric Screening/HRA - High Compensation|BEHAVIORAL: Wellness Activities - Low Compensation|BEHAVIORAL: Wellness Activities - High Compensation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Pharmacokinetics of Tezepelumab in Children With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacotherapy for HIV Infected Patients With Alcohol Problems
Status: WITHDRAWN
Conditions: HIV Infection|Heavy Alcoholic Consumption|HIV Infections
Interventions: DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and Erythropoiesis
Status: COMPLETED
Conditions: Inflammation; Muscle|Iron Metabolism|Ineffective Erythropoiesis|Healthy
Interventions: DRUG: Cholecalciferol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Liraglutide on Body Surface Gastric Mapping
Status: RECRUITING
Conditions: Gastroparesis|Functional Dyspepsia|Chronic Nausea and Vomiting Syndrome|Healthy
Interventions: DEVICE: Body Surface Gastric Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cost Effectiveness of OMT for Chronic Low Back Pain
Status: COMPLETED
Conditions: Lumbar Radiculopathy|Lesion of Sciatic Nerve, Left Lower Limb|Lesion of Sciatic Nerve, Right Lower Limb|Lumbar Spinal Stenosis|Lumbar Spondylosis|Lumbago With Sciatica, Left Side|Lumbago With Sciatica, Right Side
Interventions: PROCEDURE: Osteopathic Manipulative Treatment (OMT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glass-ionomer Cement Containing Chlorhexidine for ART
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: ART with GIC containing 1.25% CHX.|PROCEDURE: ART with GIC.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Selumetinib 50mg|DRUG: Selumetinib 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of PCOS on Periodontal Status of Adolescent and Adult Age Group Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Gingival Inflammation
Interventions: OTHER: PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADOLESCENT AGE GROUP WILL BE ASSESSED|OTHER: PERIODONTAL STATUS OF FEMALE PATIENTS WITH PCOS (NEWLY DIAGNOSED) OF ADULT AGE GROUP WILL BE ASSESSED
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Proof of Concept, Randomized Controlled, Single-Center Study of a Decision Aid Tool for Older Patients Considering LHC as Treatment for NSTEMI
Status: COMPLETED
Conditions: NSTEMI
Interventions: BEHAVIORAL: Shared Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and PK/PD of RTA 1701 in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo oral capsule|DRUG: RTA 1701 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Astrocytoma|Glioma|Recurrent Glioblastoma
Interventions: RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypercholesterolemia
Interventions: DRUG: Dapagliflozin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-term Health Benefits of Using Fresh Air Filtration System in Classroom
Status: COMPLETED
Conditions: Airway Morbidity|Cognitive and Attention Disorders and Disturbances|Oxidative Stress
Interventions: DEVICE: Fresh air system with filtration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia|Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: Asparaginase|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Study to Determine the Prevalence and Influence of Pertussis on COPD Exacerbation in Shenzhen
Status: UNKNOWN
Conditions: COPD Exacerbation|Pertussis
Interventions: PROCEDURE: Blood sample|OTHER: Data collection|PROCEDURE: Throat swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation Of Stress Response In Diabetic Hypertensive Patients
Status: COMPLETED
Conditions: Diabetes|Hypertension
Interventions: BEHAVIORAL: First arithmetic problem solving|BEHAVIORAL: Second arithmetic problem solving|BEHAVIORAL: Third arithmetic problem solving|BEHAVIORAL: Fourth arithmetic problem solving|BEHAVIORAL: Fifth arithmetic problem solving|BEHAVIORAL: Sixth arithmetic problem solving
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Xbox in the Rehabilitation of Chronic Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Balance Disorders|Attention Deficits
Interventions: DEVICE: gaming therapy (Xbox)|DEVICE: Dynamic balance platform (Biodex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Interaction Study To Assess the Effect of Food on the Pharmacokinetics of Esomeprazole 20 mg/Acetylsalicylic Acid 81 mg
Status: COMPLETED
Conditions: Effect of Food|Pharmacokinetics
Interventions: DRUG: esomeprazole/ASA Fixed Dose Combination (FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood and Marrow Transplant Clinical Research Network
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Blood Disease|Hematopoietic Stem Cell Transplantation|Leukemia|Multiple Myeloma|Myelodysplastic Syndromes|Graft vs Host Disease
Interventions: DRUG: fluconazole|DRUG: voriconazole|PROCEDURE: bone marrow transplant|DRUG: thalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B
Status: NOT_YET_RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: AD-227A|DRUG: AD-227B|DRUG: AD-227C|DRUG: Placebo of AD-227B|DRUG: Placebo of AD-227C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Education and Exercise Program for Adults With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Education and Exercise Program for Adults with Type 2 Diabetes|BEHAVIORAL: Nutrition Education plus Occupational Therapy plus Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Functional Respiratory Muscle Training on Respiratory Function and Physical Performance
Status: ENROLLING_BY_INVITATION
Conditions: Respiratory Muscle|Exercise
Interventions: OTHER: F-IMT|OTHER: Core Stabilization Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Venetoclax in CLL (ZANU-VEN)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: Venetoclax|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Referral for Healthier Survivorship in Obese Stage I-II Endometrial Cancer Survivors or Atypical Hyperplasia
Status: COMPLETED
Conditions: Complex Endometrial Hyperplasia With Atypia|Stage IA Uterine Corpus Cancer|Stage IB Uterine Corpus Cancer|Stage II Uterine Corpus Cancer
Interventions: BEHAVIORAL: Weight Loss Specialist|OTHER: Quality-of-Life Assessment|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance
Status: COMPLETED
Conditions: Opioid Dependence|Pain|Addiction
Interventions: DRUG: Placebo|DRUG: Hydromorphone|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Th2 Cells to Prevent Graft-Versus-Host Disease in Bone Marrow Transplants
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Graft vs Host Disease|Hodgkin's Disease|Multiple Myeloma|Non Hodgkin's Lymphoma
Interventions: DRUG: Th2 cells in allo HSCTT|DRUG: Th2 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Real Time 3-Dimensional Echocardiography for Left Ventricular Lead Site Selection to Reduce Cardiac Resynchronization Therapy Non-Responder Rates
Status: COMPLETED
Conditions: Heart Failure
Interventions: PROCEDURE: 3D echo-guided LV lead placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Evaluate the Long-Term Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occlusion vs Standard Treatment for the Treatment of Herpes Zoster
Status: UNKNOWN
Conditions: Herpes Zoster
Interventions: OTHER: Aluminum sulphate and calcium acetate drying soaks|DEVICE: Topical sterile silicone gel for wounds|DEVICE: Hydrocolloid dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abscess Packing Versus Wick Placement After Incision and Drainage
Status: COMPLETED
Conditions: Superficial Abscess Packing
Interventions: PROCEDURE: Full packing into abscess cavity|PROCEDURE: Wick placement into abscess cavity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone|DRUG: placebo inhalation|DRUG: Salmeterol|DRUG: fluticasone/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure
Status: COMPLETED
Conditions: Liver Failure|Critical Illness
Interventions: OTHER: Parenteral nutrition|OTHER: Enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Mesial Incision: a New Safe and Fertility-sparing Technique
Status: COMPLETED
Conditions: Dermoid Ovarian Cysts
Interventions: PROCEDURE: Laparoscopic dermoid cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer
Status: RECRUITING
Conditions: Invasive Ductal Breast Carcinoma|Invasive Ductal Carcinoma, Breast|DCIS|DCIS Grade 1|DCIS Grade 2|Breast Cancer
Interventions: RADIATION: Accelerated Partial Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Adipose Derived Stem Cell (ADSC) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monotherapy Dose Finding With BI 847325 in Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: day 1 to day 5|DRUG: day 1 to day 14
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients
Status: UNKNOWN
Conditions: Induction Chemotherapy|Acute T-Lymphocytic Leukemia|T-cell Lymphoblastic Lymphoma Leukemia|T-cell/Myeloid Mixed Phenotype Acute Leukemia
Interventions: DRUG: Decitabine combined with HAAG Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs
Status: COMPLETED
Conditions: Fracture; Rib, Multiple
Interventions: DEVICE: Ultrasound|DRUG: Bupivacaine HCl Inj 0.25%|DRUG: Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE
Status: COMPLETED
Conditions: Cardiovascular Disease|Peripheral Arterial Disease|Diabetes Mellitus|Coronary Heart Disease
Interventions: DRUG: ER niacin/laropiprant|DRUG: simvastatin|DRUG: ezetimibe/simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nepicastat for Posttraumatic Stress Disorder (PTSD) in OIF/OEF Veterans
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Nepicastat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subacromial Impingement Syndrome Functional Tests Correlation With Ultrasound Parameters
Status: RECRUITING
Conditions: Subacromial Impingement Syndrome|Shoulder Tendinitis|Shoulder Bursitis|Shoulder Pain
Interventions: DIAGNOSTIC_TEST: Shoulder functional tests and ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Access of Daratumumab Combined With VRD in the Treatment of Patients With Standard-risk Newly Diagnosed MM
Status: NOT_YET_RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Efficacy of Treatments for Anxiety and Depression Among College Students
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: External Qigong|BEHAVIORAL: Mindfulness Meditation|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Normal and Small Size Mesh in Open Inguinal Herni Repair
Status: COMPLETED
Conditions: General Surgery|Inguinal Hernia|Ventral Hernia
Interventions: PROCEDURE: Comparison of normal and small size mesh in open inguinal hernia repair: Multicenter Prospective Randomized Controlled Trial.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Faecal Microbiota Transplantation for Patients With Diabetes Mellitus Type 1 and Severe Gastrointestinal Neuropathy
Status: COMPLETED
Conditions: Faecal Microbiota Transplantation (FMT)|Diabetes Mellitus, Type 1|Gastrointestinal Neuropathy
Interventions: OTHER: Faecal microbiota transplantation (FMT) capsules|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3031207 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY3031207|DRUG: Placebo|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacity of Psychological Intervention on Reducing the Suicidal Ideations, Depression Level and Improving Reinsertion
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: OTHER: weekly psychotherapeutic individual sessions|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Research Into Memory, Genomics in the Intensive Therapy Unit: Alzheimer's
Status: UNKNOWN
Conditions: Cognitive Impairment|Apolipoprotein E, Deficiency or Defect of|Critical Illness|Burns|Young Adult
Interventions: DIAGNOSTIC_TEST: APOE genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.
Status: COMPLETED
Conditions: Diabete Type 2|Cataract|Triamcinolone Acetonide|Intravitreal Injection
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma
Status: WITHDRAWN
Conditions: Chronic Pain Due to Trauma|Spinal Cord Injuries
Interventions: DRUG: Gabapentin|DRUG: Metamizol|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium-90 Radioembolization for Cirrhosis-Associated Thrombocytopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Thrombocytopenia|Cirrhosis
Interventions: DEVICE: TheraSphere® Yttrium-90 Glass Microspheres, BTG International Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI
Status: RECRUITING
Conditions: Myocardial Infarction|Coronary Stenosis|Coronary Microvascular Dysfunction
Interventions: DRUG: Esmolol Hcl 10Mg/Ml Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetic Kidney Disease|Diabetic Nephropathy|Renal Hypoxia|Renoprotection|SGLT2 Inhibitor|Ertugliflozin
Interventions: DRUG: Ertugliflozin 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Memory Training Versus Yogic Meditation Training in Older Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Kundalini yoga and meditation|BEHAVIORAL: Memory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors
Status: RECRUITING
Conditions: Malignant Oral Cavity Neoplasm|Malignant Skull Base Neoplasm|Osteoradionecrosis
Interventions: OTHER: Contrast Agent|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Itraconazole|DRUG: Rifampin|DRUG: Golcadomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attenuation Corrected Cardiac SPECT Using the GE Hawkeye Camera System
Status: TERMINATED
Conditions: Cardiac Disease
Interventions: DEVICE: GE Attenuation Corrected Hawkeye Camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Lansoprazole (Lanton)|DRUG: Omeprezole (Losec)|DRUG: Pantoprazole(Controloc)|DRUG: Esomeprazole (Nexium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation
Status: RECRUITING
Conditions: Oxygen Toxicity|Respiratory Failure
Interventions: DEVICE: Manual Oxygen titration with Philips oximeter (SpO2 target 90%)|DEVICE: Manual oxygen titration with Nonin oximeter (SpO2 target 90%)|DEVICE: Manual Oxygen titration with Philips oximeter (SpO2 target 94%)|DEVICE: Manual oxygen titration with Nonin oximeter (SpO2 target 94%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: TAK-981|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT