pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial on SBRT Versus MWA for Inoperable Colorectal Liver Metastases (CLM)
Status: TERMINATED
Conditions: Secondary Malignant Neoplasm of Liver
Interventions: RADIATION: Stereotactic Body Radiation Therapy|PROCEDURE: Microwave Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or Paraganglioma
Status: TERMINATED
Conditions: Extra-Adrenal Paraganglioma|Metastatic Adrenal Gland Pheochromocytoma|Paraganglioma|Recurrent Adrenal Gland Pheochromocytoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients
Status: COMPLETED
Conditions: Respiratory Failure|Acute Respiratory Distress Syndrome
Interventions: BEHAVIORAL: tidal volume guided by respiratory system compliance|BEHAVIORAL: low tidal volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Stability, Variability and Mechanism of Incorporation of Lipid Mediators Into Eccrine Sweat
Status: COMPLETED
Conditions: Stability & Variability of Lipid-derived Molecules in Sweat
Interventions: DRUG: Ibuprofen|OTHER: Physiological induction of sweating|DRUG: Pilocarpine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Status: UNKNOWN
Conditions: Tramadol for Labor Analgesia
Interventions: DRUG: Tramadol Hydrochloride|DRUG: Distilled Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AD17002 Treating Poorly Controlled, Moderate to Severe Eosinophilic Asthma
Status: RECRUITING
Conditions: Eosinophilic Asthma
Interventions: DRUG: AD17002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CommunityRx for Hunger: A Hospital-Based Intervention
Status: WITHDRAWN
Conditions: Food Insecurity|Caregivers|Clinical Trial|Hunger|Health-Related Quality of Life|Patient Satisfaction
Interventions: OTHER: CommunityRx-H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Web System for Engaging Families & Doctors in Continuous Asthma Quality Improvement
Status: WITHDRAWN
Conditions: Asthma
Interventions: BEHAVIORAL: Remote Coach plus Asthma Module|BEHAVIORAL: Asthma Module- No Coach|BEHAVIORAL: CHADIS- no Asthma Module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies
Status: RECRUITING
Conditions: Diabetic Retinopathy|Retinal Vein Occlusion
Interventions: OTHER: sampling of ophthalmic liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Laparoscopic Antireflux Surgery
Interventions: PROCEDURE: laparoscopic anti-reflux surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders
Status: COMPLETED
Conditions: Sexually Transmitted Diseases|Unsafe Sex|Substance-Related Disorders
Interventions: BEHAVIORAL: PACT|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of Zalypsis (PM00104) in Subjects With Advanced Malignant Solid Tumors or Lymphoma
Status: TERMINATED
Conditions: Solid Tumors|Lymphoma
Interventions: DRUG: PM00104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study WU-CART-007 in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
Status: NOT_YET_RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: BIOLOGICAL: WU-CART-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis,Knee
Interventions: DRUG: Peri-articular TXA (15 mg/kg)|DRUG: Intraarticular TXA 2 g (40 mL)|PROCEDURE: TXA combined with multimodal local anesthetic infiltration inject into peri-articular area|PROCEDURE: TXA 40 mL inject into intraaricular knee capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of CLA on Obesity, Lung Functions, Lipid Profile and Inflammation in Women With BMI≥25
Status: COMPLETED
Conditions: Obesity|Lung Functions|Inflammation|Lipid Disorder
Interventions: DIETARY_SUPPLEMENT: Conjugated linoleic acid|DIETARY_SUPPLEMENT: High oleic acid safflower oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TXA Soaked Gelatin Sponge to Reduce Rectus Sheath Hematoma After C.S. in Patients Using Warfarin
Status: COMPLETED
Conditions: Rectus Sheath Hematoma|Cesarean Section
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Effect of STC3141 Continuous Infusion in Subjects With Severe Corona Virus Disease 2019（COVID-19）Pneumonia
Status: COMPLETED
Conditions: Severe COVID-19 Pneumonia
Interventions: DRUG: STC3141|DRUG: STC3141
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment In Acute Benign Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo|Balance; Distorted|Vestibular Disorder|Dizziness
Interventions: OTHER: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Comprehensive Rehabilitation Program Plus Chemotherapy in Postoperative NSCLC Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BEHAVIORAL: Rehabilitation Training|DRUG: TCM|OTHER: Rehabilitation Education|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Mobile Health App in Managing Pediatric Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Standard care|BEHAVIORAL: Access to the "AtopicApp" mobile application|BEHAVIORAL: Virtual oversight through the AtopicApp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health
Status: COMPLETED
Conditions: Depression|Anxiety|Post Traumatic Stress Disorder
Interventions: COMBINATION_PRODUCT: Ketamine-Assisted Psychotherapy (KAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuntive Probiotic Therapy in Treating Urinary Tract Infections in Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury|Urinary Tract Infections
Interventions: OTHER: Probiotic Lactobacillus GR-1 and RC-14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: INCB099280
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chlorhexidine on Bacteriuria
Status: UNKNOWN
Conditions: Urinary Tract Infection|Nosocomial Infection|Bacteriuria
Interventions: DRUG: Povidone-iodine|DRUG: Chlorhexidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: WHARTON JELLY ORIGINATED MESENCHIAL STEM CELL in GONARTHROSIS
Status: UNKNOWN
Conditions: Stem Cell|Gonarthrosis
Interventions: BIOLOGICAL: Wharton Jelly Originated Mesencimal Stem Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Education Program Based on the PRECEDE-PROCEED Model on the Smoking Behaviors of Nursing Students
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Multimodal Pelvic Floor Rehabilitation Program in Children With Different Types of Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence|Nocturnal Enuresis|Daytime Wetting|Pelvic Floor Disorders|Children, Only|Pediatric Disorder
Interventions: OTHER: multimodal pelvic floor rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of Rifamycin SV MMX in Treating Traveler's Diarrhea in Children Age 12 to 17 Years
Status: NOT_YET_RECRUITING
Conditions: Traveler's Diarrhea
Interventions: DRUG: Rifamycin SV MMX|DRUG: Placebo to Rifamycin SV-MMX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Duloxetine in Patients With Diabetic in Peripheral Neuropathic Pain With or Without Co-morbid Major Depressive Disorder
Status: COMPLETED
Conditions: Diabetic Neuropathies|Depressive Disorder, Major
Interventions: DRUG: Duloxetine 60 mg QD|DRUG: Duloxetine 60 mg QD|DRUG: Duloxetine 30 mg QD|DRUG: Duloxetine 30 mg QD|DRUG: Duloxetine 90 mg QD|DRUG: Duloxetine 90 mg QD|DRUG: Duloxetine 60 mg QD|DRUG: Duloxetine 60 mg QD|DRUG: Duloxetine 120 mg QD|DRUG: Duloxetine 30 mg QD|DRUG: Duloxetine 30 mg QD|DRUG: Duloxetine 120 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operating Room Air Filtration/Sterilization
Status: RECRUITING
Conditions: Surgery
Interventions: DEVICE: Functioning Aerus air filtration/sterilization|DEVICE: Deactivated Aerus air filtration/sterilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breast and Abdominal Related Morbidity of DIEP and SIEA Flaps
Status: COMPLETED
Conditions: DIEP Flap Breast Reconstruction|SIEA Flap Breast Reconstruction
Interventions: PROCEDURE: DIEP flap breast reconstruction|PROCEDURE: SIEA flap breast reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Response to Intubation
Status: UNKNOWN
Conditions: Intubation
Interventions: DRUG: Dexmedetomidine|DRUG: Esmolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy and Safety of Glufosfamide Compared With Best Supportive Care in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Glufosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Loncastuximab Tesirine + Ibrutinib in Diffuse Large B-Cell or Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Loncastuximab Tesirine|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amelioration of Adverse Ocular Side Effects of Glaucoma Medications in Glaucoma Patients Using Topical GL101
Status: COMPLETED
Conditions: Ocular Surface Disease
Interventions: DRUG: GL101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Severe and Transient Hypoxemia During Selective Intra-arterial Chemotherapy for Retinoblastoma in Children: Evaluation of the Right-sided Heart Function.
Status: UNKNOWN
Conditions: Retinoblastoma
Interventions: DIAGNOSTIC_TEST: Trans-thoracic echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
Status: RECRUITING
Conditions: TBI (Traumatic Brain Injury)|Depressive Disorder, Major|Clinical Depression|Mood Depressed|Physical Inactivity
Interventions: BEHAVIORAL: InMotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol's Effects in Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Resveratrol|DRUG: Placebo|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Child-Pugh A Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib + Pravastatin|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Analgesia, Patient-Controlled|Postoperative Pain, Acute
Interventions: PROCEDURE: lateral tap block|PROCEDURE: posterior tap block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Muscle Multi-parametric NMR Imaging Development in Aged People With Sarcopenia or Frailty Syndrome; CLINical Study
Status: UNKNOWN
Conditions: Frail Elderly Syndrome|Diabetes
Interventions: DIAGNOSTIC_TEST: Nuclear magnetic resonance (NMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treating Diabetic Lipohypertrophy With Intensive Education Versus Standard Care
Status: TERMINATED
Conditions: Insulin Injections and Lipohypertrophy
Interventions: BEHAVIORAL: Intensive Training on Best Insulin Injection Technique|BEHAVIORAL: Standard education on injection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Edema in the Knee in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Edema|Edema Leg
Interventions: OTHER: conventional physiotherapy|OTHER: exercises for the knee area|OTHER: payment oriented massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quintex® Follow-up After One Year Minimum
Status: COMPLETED
Conditions: Degenerative Disc Disease|Spondylolisthesis|Trauma|Spinal Stenosis|Deformity of Spine|Pseudoarthrosis of Spine|Cervical Spondylosis|Instability; Back
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emotion Regulation as a Moderator of Two Different Treatments for Children With ODD
Status: RECRUITING
Conditions: Oppositional Defiant Disorder
Interventions: BEHAVIORAL: Parent Management Training|BEHAVIORAL: Tuning Your Temper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 12- to 30-Year-Old Healthy Adolescents and Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Epstein-Barr Virus Infection
Interventions: BIOLOGICAL: mRNA-1189|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Assess the Impact of an Alcohol Alternative Herbal Tincture on Signs of Stress Anxiety and Sleep Quality.
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Stress
Interventions: DIETARY_SUPPLEMENT: Alcohol Alternative Herbal Tincture (Test Product)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Clinicaltrail of the Effection Which of Phrenic Block Using in Non-intubated Video-assisted Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Phrenic Nerve Paralysis
Interventions: PROCEDURE: phrenic block|PROCEDURE: no phrenic block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)|BIOLOGICAL: Recombinant COVID-19 Variant Vaccine (Sf9 Cell)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children 6-59 Months in Mirria District, Niger
Status: COMPLETED
Conditions: Malnutrition
Interventions: OTHER: Screening by mothers|OTHER: Active comparator: Screening by community health workers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study With Atezolizumab Plus Bevacizumab in Patients With Chemotherapy Resistant, MSI-like, Colorectal Cancer
Status: TERMINATED
Conditions: MSI|ColoRectal Cancer|Chemotherapy|Resistance, APC
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury|Pressure Injury
Interventions: BEHAVIORAL: Provider training|BEHAVIORAL: CAPP-FIT intervention with RA facilitation|BEHAVIORAL: CAPP-FIT implementation during maintenance phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML
Status: RECRUITING
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: DRUG: etoposide|DRUG: cyclophosphamide|RADIATION: total marrow irradiation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: allogeneic bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Terbinafine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Infusion for aGVHD Prophylaxis Transplantation
Status: UNKNOWN
Conditions: Graft-versus-host Disease|Relapse
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Artificial Intelligence in CNS Radiation Oncology
Status: ACTIVE_NOT_RECRUITING
Conditions: CNS Tumor
Interventions: DIAGNOSTIC_TEST: The images (CT, MRI, PET) used for RT planning, mid-treatment imaging as part of IGRT or disease evaluation, and response assessment/ surveillance post-RT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunity Modification of Full Term Infants According to the Type of Feeding and Mode of Delivery
Status: COMPLETED
Conditions: Innate Immunity|Newborns|Nutrition|Microbiota
Interventions: DIETARY_SUPPLEMENT: Feeding infants with fermented formula milk|OTHER: Feeding infants with standard formula milk|OTHER: Breastfeeding infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Conformal Radiotherapy (CRT) Alone Versus CRT Combined With HDR BT or Stereotactic Body Radiotherapy for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: CF-CRT combined with BT or SBRT boost.|RADIATION: CF-CRT alone|DRUG: Hormonal treatment (neoadjuvant androgen deprivation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Over Dorsolateral Prefrontal Cortex in Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence|Executive Dysfunction|Abnormal Craving for Drugs
Interventions: DEVICE: transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab and Bortezomib for Patients With Low-grade B-cell Non-hodgkin Lymphoma That Relapse After Rituximab
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkins
Interventions: DRUG: Ofatumumab and Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expectant Versus Immediate Medical Management for the Evacuation of the no Evolutionary Pregnancies Before 13 GW
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: DRUG: MIFEPRISTONE 200 mg and misoprostol 400 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lonafarnib Boosted With Ritonavir With and Without Peginterferon Alfa-2a (PEG IFN-a) in HDV (LOWR-2)
Status: COMPLETED
Conditions: Chronic Hepatitis D Infection
Interventions: DRUG: lonafarnib|DRUG: ritonavir|DRUG: Pegylated interferon-alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Whole Lung Radiotherapy for Older Patients With COVID-19 Pneumonitis
Status: UNKNOWN
Conditions: COVID-19 Pneumonitis
Interventions: RADIATION: Low dose whole lung radiotherapy for older patients with COVID-19 pneumonitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Different Doses of Influenza Vaccine in Chronic Hemodialysis Patients
Status: UNKNOWN
Conditions: ESRD|Influenza Vaccine|Seroprotection
Interventions: BIOLOGICAL: Egg-derived standard dose trivalent influenza vaccine (surface antigen, inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of FNAC in Thyroid Nodules Compared to to Surgical Specimen : QOC Experience
Status: COMPLETED
Conditions: Fine Needle Aspiration Cytology|Thyroid Diseases
Interventions: PROCEDURE: Fine Needle Aspiration Cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Irinotecan to Treat Brain Tumors
Status: TERMINATED
Conditions: High-Grade Gliomas
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LAS41003 in the Treatment of Superficial Infected Eczema
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: LAS41003|DRUG: LAS189962|DRUG: LAS189961
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Functional Improvement
Status: TERMINATED
Conditions: Myofascial Trigger Point Pain|Myofascial Pain Syndrome
Interventions: PROCEDURE: Dry needling|OTHER: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obese Men
Status: COMPLETED
Conditions: Aging|Obesity|Insulin Resistance|Hypogonadism
Interventions: DRUG: Topical testosterone gel 10 g/day
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DETErmination of the Duration of the Dual Antiplatelet Therapy by the Degree of the Coverage of The Struts on Optical Coherence Tomography From the Randomized Comparison Between Everolimus-eluting Stents(EES) Versus Biolimus A9-eluting Stents(BES)
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DEVICE: Angio-guided PCI with EES or BES|DEVICE: OCT-guided PCI with EES or BES|DEVICE: PCI with BES under angio-guide or OCT guide|DEVICE: PCI with EES under angio-guide or OCT guide|DRUG: Keep DAPT|DRUG: Discontinue DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satraplatin and Bevacizumab in Treating Patients With Metastatic Prostate Cancer Previously Treated With Docetaxel
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: satraplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Montelukast Sodium Oral Thin Film and Chewable Tablet in Fed Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Montelukast sodium oral thin films with water (T)|DRUG: Montelukast sodium chewable tablets with water (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Monoclonal Antibody, VIS410, in Subjects With Uncomplicated Influenza A
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: VIS410 low dose|DRUG: VIS410 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Two Valved Holding Chambers in Acute Wheezing
Status: RECRUITING
Conditions: Bronchitis Obstructive|Bronchiolitis; Obstruction|Bronchospasm; Bronchitis
Interventions: DEVICE: VHC 1|DEVICE: VHC 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy|Asphyxia Perinatal
Interventions: OTHER: Metabolic acidosis|DIAGNOSTIC_TEST: microRNA|OTHER: Hypothermia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease (AD)|Parkinson's Disease (PD)|Chronic Traumatic Encephalopathy (CTE)|Progressive Supranuclear Palsy (PSP)|Frontal Temporal Dementia (FTD)|Pick's Disease|Tauopathies
Interventions: DRUG: [18F]T807 ([18F]MNI-777)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Neurodevelopmental Disorders
Interventions: BEHAVIORAL: Parents and Infants Engaged
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Let´s Talk About Sleep in College Student
Status: COMPLETED
Conditions: Stress|Sleep Disturbance
Interventions: DEVICE: Non invasive neuromodulation NESA (XSIGNAL device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality-based Training Program on Improving Upper-Limb Functions in Participants With Stroke.
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Armeo®Spring ((Task-oriented upper extremity rehabilitation system)|OTHER: Conventional Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed-dose Combination of Valsartan + Rosuvastatin Versus Their Isolated Components for Hypertension and Dyslipidemia.
Status: WITHDRAWN
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: Valsartan 160mg + Rosuvastatin 20mg|DRUG: Valsartan 320mg + Rosuvastatin 20mg|DRUG: Diovan® 160mg + Crestor® 20mg|DRUG: Diovan® 320mg + Crestor® 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Link4Health: A Combination Strategy for Linkage and Retention, Swaziland
Status: COMPLETED
Conditions: HIV (Human Immunodeficiency Virus)
Interventions: PROCEDURE: POC (point-of-care) CD4+ (cluster of differentiation 4) Count|PROCEDURE: Accelerated ART (antiretroviral therapy) Initiation|BEHAVIORAL: Basic Care and Prevention Package|BEHAVIORAL: Cellular Appointment Reminders and Follow-Up|OTHER: Financial Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: interleukin 2|BIOLOGICAL: rhuMAb
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Metastatic Breast Cancer Patients Receiving Eftilagimod Alpha or Placebo in Combination With Paclitaxel Chemotherapy
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: BIOLOGICAL: eftilagimod alpha|DRUG: Paclitaxel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tremelimumab + Durvalumab(MEDI4736)+ Belinostat in ARID1A Mutated Cancer Focus on Urothelial Carcinoma
Status: SUSPENDED
Conditions: Infiltrating Urothelial Carcinoma, Sarcomatoid Variant|Locally Advanced Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Unresectable Urothelial Carcinoma
Interventions: DRUG: Belinostat|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
Status: WITHDRAWN
Conditions: Neoplasm Metastasis|Sarcoma|Neoplasms, Germ Cell and Embryonal|Melanoma
Interventions: DRUG: decitabine (DAC)|DRUG: Tetrahydrouridine (THU)|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Synvisc on Cartilage in Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Synvisc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Mulligan Mobilization Technique on Balance, Pain and Functionality in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain|Lumbal Disc Herniation|Imbalance
Interventions: OTHER: Mulligan Technique|OTHER: Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Prospective, One Arm, Feasibility, Study for The Use of Halevy Kit for the Treatment of Perianal Fistulas in Patients With Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease|Fistula
Interventions: DEVICE: Halevy kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Open-label, Drug-Drug Interaction With Maraviroc (DDI)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leflunomide for Maintenance of Remission in IgG4 Related Disease
Status: COMPLETED
Conditions: Immunoglobulin G4 Related Sclerosing Disease
Interventions: DRUG: Prednisone|DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial
Status: COMPLETED
Conditions: Brain Injury|Muscle Weakness
Interventions: BEHAVIORAL: Cognitive, physical, and functional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence
Status: RECRUITING
Conditions: Masseter Muscle Prominence
Interventions: DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Coated PTA Balloons for Treatment of Dysfunctional AV Fistulae and Grafts
Status: WITHDRAWN
Conditions: Dysfunctional AV Graft|Dysfunctional AV Fistula
Interventions: DEVICE: Lutonix Paclitaxel Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Examine the Difference Between Local Anesthetics Alone and Local Anesthetics Plus Steroids in the Treatment of Chronic Headache
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: lidocaine, bupivicaine and saline|DRUG: lidocaine plus bupivicaine plus triamcinolone (steroid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Brexpiprazole in the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Adaptations and Pharmacological Interventions in Cocaine Addiction
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DRUG: N-Acetylcystein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adenoidectomy, Myringotomy and Tubes' Insertion vs Adenoidectomy and Myringotomy Alone in Children With Otitis Media With Effusion and Adenoid Hypertrophy
Status: COMPLETED
Conditions: Otitis Media With Effusion
Interventions: PROCEDURE: adenoidectomy, myringotomy, tubes insertion|PROCEDURE: A-M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEDI4736 and Tremelimumab in Treating Patients With Metastatic HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: BIOLOGICAL: Anti-B7H1 Monoclonal Antibody MEDI4736|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketanserin After LSD Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide|DRUG: Ketanserin Placebo|DRUG: Ketanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of secukinumAb in Adult Patients With Moderate to Severe Hidradenitis Suppurativa.
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: OTHER: secukinumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: S0301 Cyclosporine, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cyclosporine|DRUG: cytarabine|DRUG: daunorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Imatinib mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Axial Length and Central Corneal Thickness in Benign Intracranial Hypertension
Status: TERMINATED
Conditions: Benign Intracranial Hypertension
Interventions: DEVICE: Pachette3|DEVICE: Lenstar-Think
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCT
Status: RECRUITING
Conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Imatinib|DRUG: Ponatinib|DRUG: Blinatumomab|OTHER: Indication for stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)
Status: COMPLETED
Conditions: Elevated Lipoprotein(a)
Interventions: DRUG: IONIS-APO(a)-LRx|DRUG: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of the Sing2016 M2SR H3N2 Monovalent Influenza Vaccine in Adults Ages 50 to 85 Years Old
Status: COMPLETED
Conditions: Influenza Vaccine
Interventions: BIOLOGICAL: Sing2016 M2SR H3N2 influenza vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Treatment of Type 2 Diabetes Mellitus in <35 Body Mass Index (BMI)
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Bariatric Surgery|Biliopancreatic Diversion|Gastric Bypass
Interventions: PROCEDURE: biliopancreatic diversion, gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix
Status: RECRUITING
Conditions: Short Cervical Length
Interventions: DRUG: Vaginal progesterone|DRUG: Placebo|DEVICE: Arabin Pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chiropractic Care Plus Physiotherapy Compared to Physiotherapy Alone in Chronic Stroke Patients
Status: COMPLETED
Conditions: Chronic Stroke
Interventions: OTHER: Experimental Group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An RCT of Concurrent and Maintenance Cediranib in Women With Platinum-sensitive Relapsed Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: cediranib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of BAC in Patient With Alzheimer's Disease or Vascular Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease or Vascular Dementia
Interventions: DRUG: BAC treatment|DRUG: Matched vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Repair With Arthroscopic Acromioplasty (Shaving the Acromion Bone) Versus Repair Without Acromioplasty
Status: COMPLETED
Conditions: Shoulder Injuries
Interventions: PROCEDURE: without acromioplasty|PROCEDURE: with acromioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: MPDL3280A|RADIATION: Hypofractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 2 Diets With Different Starch Digestibility Profiles on Daily Glycemic Profile, in T2D Patients
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: OTHER: Balanced diet high in Slowly Digestible Starch|OTHER: Balanced diet low in Slowly Digestible Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION