pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Radiation Therapy With Temozolomide and Pembrolizumab in Treating Patients With Newly Diagnosed Glioblastoma
Status: TERMINATED
Conditions: Adult Glioblastoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.
Status: COMPLETED
Conditions: Cancer|Solid Tumor|Metastatic Colorectal Cancer (mCRC)
Interventions: DRUG: Promitil|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anterior Repositioning Guided Splint Combined With or Without I Platelet-rich Fibrin
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Patients who received treatment involving ARS and arthrocentesis only|PROCEDURE: Patients who received treatment involving ARS, arthrocentesis, and an I-PRF injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vivifrail Program on the Degree of Debilitation in Hospitalized Patients After Venous Hemolysis in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke|Exercise Therapy|Frailty
Interventions: BEHAVIORAL: Multi-component Exercise Intervention Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Fasting for NAFLD in Adults
Status: RECRUITING
Conditions: Fatty Liver|Intermittent Fasting|Fatty Liver, Nonalcoholic|Non-Alcoholic Fatty Liver Disease|Liver Fat
Interventions: BEHAVIORAL: Time-Restricted, Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial Evaluating the Effect of Closed Suction Drainage Versus Straight Drainage After Distal Pancreatectomy
Status: TERMINATED
Conditions: Pancreatic Fistula
Interventions: DEVICE: Jackson-Pratt Drain|DEVICE: Non-suctioning drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blue-light Filtering Spectacle Lenses on Myopia Progression in Schoolchildren
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Blue-light filtering spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Acupoints Compatibility Difference of the Effect of Treatment of the Primary Insomnia
Status: UNKNOWN
Conditions: Primary Insomnia
Interventions: OTHER: acupuncture|OTHER: acupuncture|OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Different Entry Portal Pathways Into Primary Care for Musculoskeletal Injury
Status: UNKNOWN
Conditions: Physical Therapy Direct Access|Physical Therapy Primary Care
Interventions: OTHER: physical therapy vs. primary care interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Combination of RRT With tDCS on Dyslexic Adults
Status: UNKNOWN
Conditions: Developmental Dyslexia
Interventions: BEHAVIORAL: Rhythmic Reading Training|DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Screening Anal HPV Colonization in Men Sex Men Using Pre-exposure Prophylaxis for HIV (ANAPreP'HPV)
Status: RECRUITING
Conditions: Pre-Exposure Prophylaxis
Interventions: OTHER: A prelevement for HPV genotyping and anal cytology will be carried out in addition to the anal swabs taken quarterly to screen for other sexually transmitted infections.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of a Postpartum Lifestyle Intervention on the Cardiometabolic Risk Profile of GDM Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Dietary Modification|Weight Loss|Physical Activity|Breastfeeding
Interventions: BEHAVIORAL: Lifestyle intervention|BEHAVIORAL: Active control lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Blockade of PD-1 in Conjunction With the Dendritic Cell/AML Vaccine Following Chemotherapy Induced Remission
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myelogenous Leukemia|AML
Interventions: BIOLOGICAL: DC AML Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vinorelbine Metronomic Plus Lapatinib for Overexpressing HER-2 Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The REACTplusNMES Trial: A Double-blinded RCT
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Stroke, Cerebrovascular
Interventions: BEHAVIORAL: Reactive balance training with Neuromuscular Electrical Stimulation|BEHAVIORAL: Reactive balance training without Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of NPC-01 to Treat Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: NPC-01|DRUG: IKH-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol Sedation During Upper Endoscopy With and Without Topical Pharyngeal Anesthesia
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Lidocaine 10%|DRUG: Diluted gentian root solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors
Status: NOT_YET_RECRUITING
Conditions: Sexual Dysfunction|Stem Cell Transplant Complications|Bone Marrow Transplant Complications
Interventions: BEHAVIORAL: SHIFT Intervention Group|BEHAVIORAL: Enhanced Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decision Support for BRCA Testing in Ethnically Diverse Women
Status: COMPLETED
Conditions: Breast Cancer|BRCA1 Mutation|BRCA2 Mutation|Ovarian Cancer
Interventions: OTHER: RealRisks|OTHER: BNAV|OTHER: iNYP|OTHER: Standard Educational Material|OTHER: High-Risk Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Trial of a WT-1 Analog Peptide Vaccine in Patients With Myeloid Neoplasms
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: WT-1|DRUG: Montanide|DRUG: Sargramostim (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Techniques of Quadratus Lumborum Block
Status: UNKNOWN
Conditions: Nerve Block
Interventions: PROCEDURE: transverse scan, in-plane, posterior- anterior quadratus lumborum block|PROCEDURE: paramedian sagittal longitudinal scan, in-plane, caudal-cranial quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: HFNO Versus Nasal CPAP in Obese Patients Undergoing Deep Sedation for ERCP
Status: NOT_YET_RECRUITING
Conditions: Obese
Interventions: DEVICE: high flow nasal oxygen device (HFNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Attention Bias Modification Treatment (ABMT) for Patients With Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Attention Bias Modification Treatment (ABMT)
Interventions: BEHAVIORAL: Attention Bias Modification Treatment (ABMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 Serum in COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Administration of Equine immunoglobulin anti SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Herbal Therapy Combined With Acupuncture for Female Mixed Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: COMBINATION_PRODUCT: Chinese herb & acupuncture|COMBINATION_PRODUCT: Chinese herb & sham acupuncture|COMBINATION_PRODUCT: Placebo & acupuncture|OTHER: Placebo & sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Belgian Study to Assess the Efficacy and Safety of the RESTORER Iliac Stent for Treatment of Aorto-iliac Lesions.
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Restorer Iliac Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Yili Lactoferrin ShuHua Milk in the Improvement of Human Immunization
Status: COMPLETED
Conditions: Immunization|Human Influenza|Common Cold
Interventions: DIETARY_SUPPLEMENT: Yili Lactoferrin ShuHua Milk (Lactoferrin 5mg/100ml)|DIETARY_SUPPLEMENT: Yili Lactoferrin ShuHua Milk (Lactoferrin 10mg/100ml)|DIETARY_SUPPLEMENT: Recombined low protein milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: Zoledronic Acid|BIOLOGICAL: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Study Of Ropinirole In Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Placebo|DRUG: Ropinirole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INhalation of Flecainide to Convert Recent Onset SympTomatic Atrial Fibrillation to siNus rhyThm (INSTANT)
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation (PAF)
Interventions: DRUG: Flecainide Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Dual Therapy (Lopinavir/Ritonavir + LamivudinE) in Treatment-Experienced HIV Infected Patients in the Russian Federation
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: lopinavir/ritonavir|DRUG: lamivudine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Efficacy and Tolerability of the Use of Vitatonus Dexa Compared to Dexamethasone in Patients With Neuralgia of Various Origins
Status: UNKNOWN
Conditions: Neuralgia
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of Alefacept to Treat Palmar Plantar Pustulosis
Status: COMPLETED
Conditions: Psoriasis|Palmoplantaris Pustulosis|Pustular Psoriasis of Palms and Soles|Pustulosis Palmaris et Plantaris|Pustulosis of Palms and Soles
Interventions: DRUG: Alefacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability and Preliminary Efficacy of EHP-101 in Relapsing Forms of Multiple Sclerosis
Status: SUSPENDED
Conditions: Relapsing Forms of Multiple Sclerosis
Interventions: DRUG: EHP-101 25 mg OD|DRUG: EHP-101 25 mg BID|DRUG: EHP-101 50 mg OD|DRUG: EHP-101 50 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of PF-06939926 Gene Therapy in Duchenne Muscular Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: PF-06939926
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: sFlt-1/PlGF Ratio: Impact on the Management of Patients With Suspected Pre-eclampsia
Status: RECRUITING
Conditions: Pre-Eclampsia
Interventions: OTHER: sFlt-1/PlGF ratio - Active Comparator: Standard|OTHER: sFlt-1/PlGF ratio - Experimental: Biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter, Open-label, Dose-finding Trial of OPC-41061 to Investigate Efficacy, Pharmacokinetics, Pharmacodynamics, and Safety in Patients With Carcinomatous Edema (Phase 2)
Status: COMPLETED
Conditions: Carcinomatous Edema
Interventions: DRUG: OPC-41061
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Upper Extremity Aerobic Exercise Training in Hematopoietic Stem Cell Transplantation Recipients
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Aerobic Exercise
Interventions: OTHER: Upper Extremity Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Oral Contraceptive Pills On Eyes
Status: COMPLETED
Conditions: Adverse Effect of Oral Contraceptives, Subsequent Encounter
Interventions: DRUG: oral contraceptive pills
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ixabepilone in Treating Patients With Metastatic, Recurrent, or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage III Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: ixabepilone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Prevention Pilot Trial for Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: A highly hydrolyzed formula|DIETARY_SUPPLEMENT: A regular cow's milk based formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prediction Model of Improvement of Disturbance of Consciousness in Patients With Hydrocephalus After Shunt Operation
Status: UNKNOWN
Conditions: Disorder of Consciousness|Hydrocephalus
Interventions: PROCEDURE: Cerebrospinal fluid shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Study of Autologous Tumor Infiltrating Lymphocyte Injection (GT316) in the Treatment of Advanced Solid Tumors (Gynecological Tumors)
Status: RECRUITING
Conditions: Solid Tumor|Gynecological Tumors
Interventions: BIOLOGICAL: GT316
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness, Safety and Feasibility of Auxiliary Nurse Midwives' (ANM) Use of Oxytocin in Uniject™ to Prevent Postpartum Hemorrhage in India
Status: WITHDRAWN
Conditions: Postpartum Hemorrhage
Interventions: OTHER: Oxytocin in Uniject
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pain Elimination and Anxiety Control Through Experiential Virtual Reality
Status: NOT_YET_RECRUITING
Conditions: Procedural Pain|Procedural Anxiety
Interventions: DEVICE: Active Virtual Reality|DEVICE: Passive Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Early Nutrition Support in Severe Stroke-2
Status: RECRUITING
Conditions: Severe Stroke|Acute Stroke|Dysphagia
Interventions: PROCEDURE: Trophic enteral feeding combined with supplemental parenteral nutrition|PROCEDURE: Full enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Cognitive Resilience Study
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: Cognitive stress tests during functional MRI|OTHER: Cognitive stress tests during gait task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Brain Blood Flow Responses to Stress: Sex Differences
Status: RECRUITING
Conditions: Cerebrovascular Disorders
Interventions: DRUG: Indomethacin|DRUG: Placebo|DRUG: Orilissa|DRUG: Testosterone gel|DRUG: Anastrozole|DRUG: Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: PROCEDURE: Conventional Surgery|DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incentivizing Meditation App Habit Formation
Status: COMPLETED
Conditions: Stress|Adherence, Treatment
Interventions: BEHAVIORAL: AC+ARwdC|BEHAVIORAL: AC+RwdC|BEHAVIORAL: Usual Calm Control (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Effect of Edaravone in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Neuromuscular Diseases
Interventions: DRUG: Edaravone|DRUG: Riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson's Disease Subjects
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Sinemet 25-100 Oral Tablet|DRUG: XP21279|DRUG: Carbidopa Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arterial Dissections After Angioplasty by Long vs Short Time of Balloon Inflation: the Randomized Controlled Trial.
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Dissection Arterial
Interventions: PROCEDURE: Percutaneous transluminal angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
Status: RECRUITING
Conditions: Peripheral Vestibular Disorder|Benign Paroxysmal Positional Vertigo|Meniere Disease|Vestibular Neuritis|Vestibular Neuronitis|Labyrinthitis|Herpes Zoster Oticus
Interventions: BEHAVIORAL: Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation|BEHAVIORAL: Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Is the Use of Blood Platelets Effective in the Treatment of Difficult Fistulas Related to the Anal Sphincter?
Status: UNKNOWN
Conditions: Rectal Fistula
Interventions: PROCEDURE: Mucosa advancement flap|OTHER: Platelet rich plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis Therapy
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: LPV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Uritos®|DRUG: Urotol®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Bath in Patients Submitted to Hip Arthroplasty
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: 4% Chlorhexidine gluconate|DEVICE: 10% PVPI degermante|DEVICE: Soap without antiseptic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilates and the Pelvic Floor: A Quasi-experimental Study
Status: COMPLETED
Conditions: Pregnancy|Perineum; Injury|Pilates Method|Episiotomy Wound
Interventions: OTHER: PILATES METHOD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma|Brain Tumor
Interventions: DRUG: Avastin|DRUG: Temozolomide|RADIATION: Radiation Therapy (XRT)|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: COMBINATION_PRODUCT: Donepezil + Cognitive remediation therapy (CRT)|COMBINATION_PRODUCT: Donepezil + Placebo CRT|COMBINATION_PRODUCT: Placebo medication + Cognitive remediation therapy (CRT)|COMBINATION_PRODUCT: Placebo medication + Placebo CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Randomized, Cross-Over, Vehicle-Controlled, Double-Blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DRUG: GHRP-1/AG 70 mg depot in ESRD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Status: COMPLETED
Conditions: Postoperative Pain, Acute|Regional Anesthesia|Multimodal Analgesia
Interventions: PROCEDURE: Bilateral Erector spinae plane block|PROCEDURE: Unilateral Erector spinae plane block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy
Status: COMPLETED
Conditions: Barrett Esophagus|Gastric Antrectomy Partial|Biliary Duct Stricture|Pancreatic Duct Stricture|Colorectal Polyps|Esophageal Neoplasms|Head and Neck Neoplasms
Interventions: PROCEDURE: Confocal endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Interventional Research With Mixed Methods on an Early Integrated Palliative Approach in Nursing Home
Status: UNKNOWN
Conditions: Palliative Care|Nursing Homes|Aged
Interventions: OTHER: early integrated palliative approach model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Dastatuz Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Food Preferences|Food Habits|Food Selection
Interventions: BEHAVIORAL: SD_SF|BEHAVIORAL: SD_BLW|BEHAVIORAL: HFV_SF|BEHAVIORAL: HFV_BLW
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Weight Loss Interventions for Overweight Breast Cancer Survivors
Status: COMPLETED
Conditions: Overweight|Postmenopausal|Breast Cancer
Interventions: BEHAVIORAL: weight loss intervention|BEHAVIORAL: Weight Loss|BEHAVIORAL: Weight Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sulphonylurea Receptor Mutation and Responsiveness to Gliclazide - a Pilot Proof of Concept, Randomised Cross-over Study
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Gliclazide|DRUG: Glibenclamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Cognitive Adaptive E-treatment in Schizophrenia-diagnosed Adults
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Plasticity-based Cognitive Training|OTHER: Non-plasticity-based Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Characteristics of Acute Renal Failure in Intensive Care on the Long-term Renal Prognosis: Prospective Multicenter Cohort Study
Status: RECRUITING
Conditions: Acute Kidney Injury|Transient Acute Renal Failure|Persistent Acute Renal Failure
Interventions: BIOLOGICAL: Data observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Metoprolol and pyronaridine-artesunate|DRUG: pyronaridine-artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS)
Status: RECRUITING
Conditions: Myalgia
Interventions: DRUG: Diosmin750|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273.214|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of EverOn™ - A Contact-Free System for Measuring Heart Rate, Respiratory Rate and Motion
Status: WITHDRAWN
Conditions: Post Surgical Pat., Medical Pat., Resp. Failure, Car.Arrest, Death
Interventions: DEVICE: EverOn (EarlySense) contactless monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: behavioral dietary intervention|DIETARY_SUPPLEMENT: omega-3 fatty acid|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant Human Adenovirus Type 5 Plus HAIC of FOLFOX for Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: Recombinant Human Adenovirus Type 5|DRUG: HAIC of FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Abatacept|DRUG: Adalimumab|DRUG: Azathioprine|DRUG: Baricitinib|DRUG: Certolizumab|DRUG: Etanercept|DRUG: Golimumab|DRUG: Hydroxychloroquine|DRUG: Infliximab|DRUG: Leflunomide|DRUG: Minocycline|DRUG: Rituximab|DRUG: Sarilumab|DRUG: Sulfasalazine|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Acids and Cardio - Vascular Complications in Patients With Chronic Kidney Disease in Stage 1-3
Status: UNKNOWN
Conditions: Chronic Kidney Disease|Cardiovascular Complications
Interventions: DIETARY_SUPPLEMENT: Gold omega 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: florbetapir (18F)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIIA-IIIB Resectable NSCLC (FORESEE)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Furmonertinib+cisplating/pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants
Status: COMPLETED
Conditions: Neurodevelopmental Disorder|Bilateral Inguinal Hernia
Interventions: DRUG: Dexmedetomidine sedation|DRUG: General sevoflurane anaesthesia|PROCEDURE: Caudal anaesthesia|PROCEDURE: Inguinal hernia surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Refametinib (BAY86-9766)|DRUG: Sorafenib (BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Status: RECRUITING
Conditions: Pain, Postoperative|Osteoarthritis Thumb
Interventions: DRUG: NSAID capsules|DRUG: Opioid capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Siriraj Home Exercises Protocol for Primary Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Siriraj knee exercise|OTHER: Physical modalities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls
Status: RECRUITING
Conditions: Frailty|Fall|Frailty Syndrome|Falls
Interventions: DRUG: Nicotinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Changes in Positron Emissions Tomography (PET/CT) Scan as Predictors of Clinical Outcome in NSCLC Treated With EGFR Tyrosin Kinase Inhibitors (TKI)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Patients
Interventions: PROCEDURE: 18F-FDG-PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)
Status: NOT_YET_RECRUITING
Conditions: Tricuspid Valve Regurgitation|Heart Valve Diseases|Cardiovascular Diseases
Interventions: DEVICE: Transcatheter Tricuspid Valve Replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LED Treatment to Improve Cognition and Promote Recovery in TBI
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury|Posttraumatic Stress Disorder
Interventions: OTHER: LED|OTHER: sham LED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Status: NOT_YET_RECRUITING
Conditions: Hypertensive Disorders of Pregnancy|Preeclampsia|Gestational Hypertension
Interventions: DRUG: Aspirin 81 mg|DRUG: Aspirin 162 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Rehabilitation Exercise Plan at Home to Treat Post-stroke Patients in the Chronic Phase
Status: RECRUITING
Conditions: Stroke|Motor Disorders|Physical Disability
Interventions: DEVICE: Rehabilitation treatment using Muvity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Relapsed and/or Refractory Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: CA102N|DRUG: TAS-102|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Carcinoma|Lung Adenocarcinoma|Recurrent Non-Small Cell Lung Carcinoma|Recurrent Small Cell Lung Carcinoma|Squamous Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Auranofin|DRUG: Sirolimus|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: PROCEDURE: Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride.|PROCEDURE: Self-etching Dentine Bonding Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Ticagrelor on Coronary Blood Flow in Healthy Male Subjects.
Status: COMPLETED
Conditions: Blood Flow Speed|Coronary Flow Velocity
Interventions: DRUG: AZD6140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CONFIRM: Magnetic Resonance Guided Radiation Therapy
Status: RECRUITING
Conditions: Gastric Cancer|Invasive Breast Cancer|in Situ Breast Cancer|Mantle Cell Lymphoma|Larynx Cancer|Bladder Cancer
Interventions: RADIATION: Viewray MRIdian® Linac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Aggressive Adult T-cell Leukemia-lymphoma (ATLL)
Status: COMPLETED
Conditions: Adult T-cell Leukemia|Lymphoma
Interventions: DRUG: VCAP-AMP-VECP with G-CSF and intrathecal prophylaxis|DRUG: biweekly-CHOP with G-CSF and intrathecal prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pressure Ulcer Education on the Knowledge Level of the Relatives of the Patients
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Training group Face-to-face pressure ulcer training|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Asymptomatic Bacteriuria in Early Kidney Transplantation Follow up
Status: COMPLETED
Conditions: Asymptomatic Bacteriuria|Kidney Transplant Infection
Interventions: DIAGNOSTIC_TEST: Urinary culture and treatment if asymptomatic bacteriuria is detected
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Laughter Therapy on Surgical Stress, Oxygen Saturation, Pain and Comfort Level
Status: COMPLETED
Conditions: Bariatric Surgery Pateints|Lauhgter Therapy|Laughter Yoga
Interventions: OTHER: Laughter Therapy Based on Kolcaba Comfort Theory
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virtual Reality Intervention for Stress, Resilience, and Blood Pressure Management in Black Women - Realist Women Study
Status: NOT_YET_RECRUITING
Conditions: Stress|Hypertension
Interventions: OTHER: VR Stress Management|BEHAVIORAL: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Brinzolamide Ophthalmic Suspension Versus Placebo in the Treatment of Infantile Nystagmus Syndrome
Status: COMPLETED
Conditions: Infantile Nystagmus Syndrome
Interventions: DRUG: topical brinzolamide 1% in 5mL ophthalmic medication|DRUG: Placebo in 5 mL dispenser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Tazarotene Cream 0.05% to TAZORAC® (Tazarotene) Cream 0.05% and Both to a Placebo Control in the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Tazarotene Cream 0.05%|DRUG: TAZORAC® (tazarotene) Cream 0.05%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: Ketamine|OTHER: Saline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Sorafenib and Pegylated Interferon α2b in Stage IV Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Sorafenib|DRUG: pegylated interferon α-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: metoprolol succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise in Air Pollution and Lung Health in Asthmatics
Status: COMPLETED
Conditions: Exercise-induced Bronchoconstriction|Air Pollution
Interventions: OTHER: Rest (Sitting on chair)|OTHER: Cycling exercise|DRUG: Salbutamol inhalation|DRUG: Placebo inhalation|OTHER: Diesel Exhaust Exposure|OTHER: Filtered air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concurrent Chemotherapy for the Intermediate Risk Nasopharyngeal Carcinoma In Intensity-modulated Radiotherapy Era
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: IMRT|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisone Administration in Quiescent COPD Patients to Determine the Effect on Gene Expression
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Correlation Between Reticulated Platelets and Major Adverse Cardiac and Cerebrovascular Events After Noncardiac Surgery
Status: COMPLETED
Conditions: Cardiac Death|Congestive Heart Failure|Angina Pectoris|Stroke|Pulmonary Embolism|Deep Vein Thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: Sublingual orally disintegrating olanzapine (SODO)|DRUG: Oral olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an Assisted Fluid Management System on Microvascular Parameters
Status: COMPLETED
Conditions: Monitoring
Interventions: DEVICE: Use of a decision support system on the EV1000 monitoring (AFM mode)|OTHER: Manual application of the GDFT protocol (standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intra-articular Doxycycline: A Novel Treatment of Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis|Adhesive Capsulitis of Unspecified Shoulder|Frozen Shoulder
Interventions: DRUG: Methylprednisolone Injectable Product|DRUG: Doxycycline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: AML|Acute Myeloid Leukemia
Interventions: DRUG: Chidamide|DRUG: Venetoclax|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Impact of Arm Abduction and Adduction on the Intravascular Electrocardiograph During PICC Placement and the Tip Location Changes Related to it
Status: UNKNOWN
Conditions: Catheterization, Peripheral|Catheterization, Central Venous
Interventions: PROCEDURE: arm abduction and adduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE