pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exercise Training in Coronary Artery Disease Patients After Stenting
Status: COMPLETED
Conditions: Stent Restenosis|Coronary Artery Disease
Interventions: OTHER: Structured In-Patient and Home plan|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Using Prontosan to Treat Bacterial Biofilm
Status: RECRUITING
Conditions: Irrigation Solution|Chronic Wound|Pressure Injury|Diabetic Foot Ulcer|Burns
Interventions: DEVICE: Prontosan Wound Irrigation Solution|DEVICE: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Vitamin D as an Add-on Therapy to Corticosteroids in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Vitamin D3|DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of Cabazitaxel in Patients With Non Seminomatous Germ-cell Tumors
Status: UNKNOWN
Conditions: Non-seminomatous Germ-cell Tumors
Interventions: DRUG: Cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Disulfiram|DIETARY_SUPPLEMENT: Copper gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketamine on Production of Inflammatory Markers in Post Operative Patients in Mulago Hospital
Status: UNKNOWN
Conditions: Post Operative Inflammatory Marker Levels
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
Status: COMPLETED
Conditions: Chronic Rhinitis
Interventions: DEVICE: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Turkish Validation of The Drooling Impact Scale
Status: UNKNOWN
Conditions: Hypersalivation|Cerebral Palsy
Interventions: OTHER: Drooling Impact Scale|OTHER: Drooling Frequency and Severity Scale|OTHER: The Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD™)|OTHER: Drooling Quotient (DQ)|OTHER: Patient and caregiver visual analog scale (VAS) for drooling|OTHER: Functional Oral Intake Scale (FOIS)|OTHER: number of bibs daily used|OTHER: number of hospital admissions per year related to respiratory infections|OTHER: Gross Motor Function Classification System (GMFCS)|OTHER: Manual Ability Classification System (MACS)|OTHER: Communication Function Classification System (CFCS)|OTHER: Eating and Drinking Ability Classification System (EDACS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Study of KX-826 With Adult Male Patients With AGA
Status: ACTIVE_NOT_RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: KX-826-（5%） BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is the Routine Pressure Dressing After Thyroidectomy Necessary?
Status: COMPLETED
Conditions: Thyroid Neoplasms|Thyroid Nodules|Graves Disease|Goiter
Interventions: PROCEDURE: Normal dressing|PROCEDURE: Pressure dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reflexology and Pelvic Floor Muscle Exercises (Kegel) on Urinary Incontinence in MS Patients
Status: UNKNOWN
Conditions: Multiple Sclerosis|Reflexology|Urinary Incontinence
Interventions: OTHER: Reflexology and kegel exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Skin Refrigerant to Reduce the Pain Associated With IV Insertion
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ethyl Chloride Topical Aerosol Anesthetic|DRUG: Nature's Tears Sterile Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: FDG-PET|PROCEDURE: spirometry|PROCEDURE: bronchoscopy with BAL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Efficacy and Safety of Etanercept and Acitretin in Korean Patient With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Psoriasis
Interventions: DRUG: Etanercept|DRUG: Etanercept + Acitretin|DRUG: Acitretin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography-guided and Surgical Rectus Sheath Block in Single-port Access Laparoscopy
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: Rectus sheath block|DRUG: Ropivacaine|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide
Status: TERMINATED
Conditions: Chronic Kidney Disease|Hypertension
Interventions: DRUG: Procedure: Regional phenylephrine arterial infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Distance-Based Cognitive-Behavioural Therapy for High Anxiety Sensitivity: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Anxiety Sensitivity
Interventions: OTHER: Distance-based Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality Techniques on the Effects on Cognition in People With Cancer
Status: RECRUITING
Conditions: Cancer|Cognitive Impairment
Interventions: BEHAVIORAL: Behavioral: ONCOBrain_ImmersiveVR|BEHAVIORAL: Behavioral: Control_Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Coadministered to Healthy Subjects in the Fasted State
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Somnodent vs Herbst in Mild and Moderate OSA Patients
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Somnodent® (Oral appliance therapy)|DEVICE: Herbst® (Oral appliance therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Amphotericin B in the Treatment of Fungal Infections of the Mouth in HIV-Infected Patients Who Have Not Had Success With Fluconazole
Status: COMPLETED
Conditions: Candidiasis, Oral|HIV Infections
Interventions: DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sericin and Chitosan Cream for Preventing and Limiting the Progressive of Pressure Sore
Status: UNKNOWN
Conditions: Pressure Ulcer
Interventions: OTHER: sericin and chitosan cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO)
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: Metformin Hydrochloride 850 mg Tablets|DRUG: AC-T chemotherapy regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fertility Life Counselling Aid- FeLiCiA
Status: COMPLETED
Conditions: Infertility/Sterility|Psychological Distress|Psychological Stress|Anxiety Disorders|Depressive Disorder
Interventions: BEHAVIORAL: Fertility Life Counselling Aid (FeLiCiA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing the Floreciendo Sexual and Reproductive Health Workshop for Latina Teens and Female Caregivers: A Pilot
Status: RECRUITING
Conditions: Sexual Risk Behavior|Sexually Transmitted Infections|Unplanned Pregnancy
Interventions: BEHAVIORAL: Floreciendo (Foundations, Condoms & Contraception, Family Strengthening, and Gender & Relationships)|BEHAVIORAL: Floreciendo (Foundations, Condoms & Contraception, and Family Strengthening)|BEHAVIORAL: Floreciendo (Foundations, Condoms & Contraception, Gender & Relationships)|BEHAVIORAL: Floreciendo (Foundations, Family Strengthening, and Gender & Relationships)|BEHAVIORAL: Floreciendo (Foundations and Condoms & Contraception)|BEHAVIORAL: Floreciendo (Foundations and Family Strengthening)|BEHAVIORAL: Floreciendo (Foundations and Gender & Partner Relationships)|BEHAVIORAL: Floreciendo (Foundations)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Radiation-Induced Mucositis
Interventions: DRUG: Opioids|DRUG: PAiN - multimodal analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: OTHER: Survey Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Docetaxel, Doxorubicin and Cyclophosphamide Versus Vinorelbine and Capecitabine in Patients Not Sufficiently / Sufficiently Responding as Preoperative Treatment of Locally Advanced or Operable Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: TAC|DRUG: NX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution of Oxidative Stress in Coronary Patients With Moderate Sleep Apnea Syndrome After Treatment With Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Sleep Apnea Syndrome|Coronary Artery Disease
Interventions: DEVICE: Continuous positive airway pressure|DEVICE: Sham-continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order
Status: TERMINATED
Conditions: Psychotic Disorders|Antisocial Personality Disorder|Impulse Regulation Disorder|Intermittent Explosive Disorder
Interventions: DRUG: naratriptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of the Sensory Integration Approach on Balance and Motor Coordination in Children With Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome
Interventions: OTHER: sensory integration approach|OTHER: traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Pvs25-IMX313/Matrix-M1 Vaccine
Status: TERMINATED
Conditions: Malaria, Vivax
Interventions: BIOLOGICAL: Pvs25-IMX313/Matrix-M1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Syphilis Response to Higher Penicillin Dosage: The 2.4 Versus 7.2 Study
Status: COMPLETED
Conditions: Syphilis
Interventions: DRUG: Benzathine penicillin G intramuscular 7.2 million units|DRUG: Benzathine penicillin G intramuscular 2.4 million units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anthocyanins on Metabolic Profiles in Subjects With Pre-diabetes
Status: COMPLETED
Conditions: Insulin Resistance|Glucose Metabolism Disorders|Type 2 Diabetes|Lipid Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: Anthocyanins|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Tacrolimus (TAC) and Mycophenolate Mofetil (MMF) for Induction of Remission in Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Tacrolimus vs. Mycophenolate mofetil for Induction Therapy in Lupus Nephritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locus-coeruleus Function in Normal Elderly and AD Risk
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Nocturnal polysomnography (NPSG)|PROCEDURE: Lumbar Puncture (LP)|OTHER: PET-MR measurement with a norepinephrine transporter (NET)-selective radiotracer (S,S)-[11C]Omethylreboxetine ([11C]MRB)|BEHAVIORAL: Psychomotor Vigilance Task (PVT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: DRUG: IGIV-C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled Molecular Hydrogen on Recovery Process After Downhill Walking on the Treadmill
Status: COMPLETED
Conditions: Muscle Soreness|Muscle Fatigue|Oxidative Stress|Inflammation
Interventions: OTHER: Molecular hydrogen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention
Status: RECRUITING
Conditions: Obesity|Overweight|Weight Loss|Health Behavior
Interventions: BEHAVIORAL: Core behavioral weight loss intervention|BEHAVIORAL: Self-monitoring diet|BEHAVIORAL: Self-monitoring weight|BEHAVIORAL: Self-monitoring steps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: carvedilol controlled release/lisinopril|DRUG: lisinopril + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiation in Aortic Valvuloplasty - ARAVA
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Balloon Aortic Valvuloplasty|PROCEDURE: External Beam Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Indacaterol vs Tiotropium in Women With COPD Secondary to Biomass Exposure
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Indacaterol|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cetuximab Plus Cisplatin in Treating Patients With Metastatic or Recurrent Cancer of the Head and Neck That Has Not Responded to Cisplatin Chemotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: levonorgestrel/EE 0.15/0.03 and EE 0.01 mg tablets|DRUG: levonorgestrel/EE 0.15/0.03 mg tablets and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity
Status: ENROLLING_BY_INVITATION
Conditions: Overweight and Obesity|Lupus Erythematosus
Interventions: DIETARY_SUPPLEMENT: Vitamin B12 + folic acid supplementation|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients
Status: RECRUITING
Conditions: Esophageal Cancer|Gastrointestinal Dysfunction
Interventions: OTHER: acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)
Status: COMPLETED
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Relacorilant|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (De)Prescribing in Hospitalized Sarcopenic Geriatric Patients
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: OTHER: deprescribing pharmacotherapy approach (DPA)|OTHER: STOPP-START deprescribing approach (SSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of A Proprietary Spearmint Extract on Cognitive Performance
Status: COMPLETED
Conditions: Mood|Cognitive Performance|Sleep
Interventions: DIETARY_SUPPLEMENT: Proprietary spearmint extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sacituzumab Govitecan in Primary HER2-negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-negative Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disease Status in Primary Sclerosing Cholangitis by Elastography
Status: UNKNOWN
Conditions: Primary Sclerosing Cholangitis|Elastography|Hepatic Fibrosis|Magnetic Resonance Imaging
Interventions: DEVICE: MR Elastography (MRE) and FibroScan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALS-008176|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy
Status: COMPLETED
Conditions: HIV Infection|Antiretroviral Side Effects|Lipodystrophy Syndrome Related to HIV Infection
Interventions: DEVICE: Eutrophill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics, Safety and Tolerability of GSK1349572 (Dolutegravir, DTG) in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK1349572
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect Of The System In The Enriched Fat Metabolism Of The Child Reached Mitochondrial Cytopathy
Status: COMPLETED
Conditions: Mitochondrial Cytopathies Disorders
Interventions: OTHER: high fat diet|OTHER: normal fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Versus Vaginal Misoprostol for Third Trimester Induction of Labor
Status: TERMINATED
Conditions: Pregnancy
Interventions: DRUG: Buccal Misoprostol|DRUG: Vaginal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Micrometastases in Patients With Stage I or Stage II Localized Colon Cancer That Can Be Removed by Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin|OTHER: active surveillance|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: lymph node mapping|PROCEDURE: sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A SAD, MAD and Food Effect Study to Evaluate the Safety, Tolerability, PK, and PD of AJA001 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AJA001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imodium Syrup Versus Imodium Tablets for Faecal Incontinence
Status: WITHDRAWN
Conditions: Fecal Incontinence
Interventions: DRUG: Imodium (Loperamide Hydrochloride) syrup|DRUG: Imodium (Loperamide hydrochloride) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma
Status: COMPLETED
Conditions: Metastatic Cancer|Sarcoma
Interventions: BIOLOGICAL: sargramostim|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline in Early Parkinson's Disease Patients Not Treated With Levodopa in China
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: rasagiline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Durvalumab|DRUG: Danvatirsen|DRUG: Oleclumab|DRUG: MEDI5752|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Nab-paclitaxel|DRUG: AZD2936
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia and Related Disorders|Mitochondrial Alteration|Cognitive Impairment
Interventions: DRUG: MitoQ|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
Status: NOT_YET_RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Affective Psychosis|Mania|Manic Disorder|Manic State
Interventions: DRUG: Quetiapine 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of NMES and Exercise in Hematological Cancer
Status: COMPLETED
Conditions: Hematologic Malignancy|Muscle Weakness
Interventions: DEVICE: Neuromuscular Electrical Stimulation|OTHER: Structured Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lacidipine In Mild To Moderate Essential Hypertension Patients With Type 2 Diabetes In Korea
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Essential Hypertension
Interventions: DRUG: Lacidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dutch Asymptomatic Mitral Regurgitation Trial
Status: TERMINATED
Conditions: Heart; Disease, Mitral(Valve)|Diseases of Mitral Valve|Mitral Valve Insufficiency
Interventions: OTHER: Watchful waiting|PROCEDURE: Early mitral valve repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Darolutamide +/- Radiation Therapy for Patients With a Castration Resistant Cancer and Metastases Detected by Functional Imaging
Status: NOT_YET_RECRUITING
Conditions: Prostatic Cancer, Castration-Resistant
Interventions: DRUG: Darolutamide 300 mg|RADIATION: Stereotactic body radiation therapy|DRUG: Androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomic Study on PKD/PKC of Dabigatran Etexilate and Rivaroxaban
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: D->R->C+R|DRUG: D->R->C+D|DRUG: R->D->C+D|DRUG: R->D->C+R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding
Status: UNKNOWN
Conditions: Endoscopic Hemostasis|Sedation
Interventions: DRUG: Propofol|DRUG: Remimazolam besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Matching Donor Human Milk On Maternal Secretor Status (MMOMSS) Study
Status: RECRUITING
Conditions: Microbial Colonization|Preterm Birth
Interventions: OTHER: Matched donor human milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Increased Parent Presence in the Neonatal Intensive Care Unit on Parent & Infant Outcomes
Status: COMPLETED
Conditions: Family Relationship|Stress|Breastfeeding|Bottle Feeding|Complications
Interventions: OTHER: FCC intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Methotrexate|DRUG: Methotrexate|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Single and Repeat Doses of IV GSK2251052 in Healthy Male Japanese and Caucasian Subjects and Repeat Doses of Supratherapeutic Doses of IV GSK2251052 in Healthy Volunteers
Status: TERMINATED
Conditions: Community-acquired Infection
Interventions: DRUG: GSK2251052 750 mg|DRUG: GSK2251052 1500 mg|DRUG: GSK2251052 1500 mg BID|DRUG: GSK2251052 2250 mg|DRUG: GSK2251052 3000 mg|DRUG: GSK2251052 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Desensitization and Cross-Desensitization During Oral Grass or Ragweed Pollen Immunotherapy
Status: TERMINATED
Conditions: Immunologic Desensitization
Interventions: DRUG: allergen extract tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identifying Biological Markers for Altitude Exposure and Use of Recombinant Human Erythropoietin (rHuEPO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: OTHER: Sea level|OTHER: Altitude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Extended-Release Naltrexone to Treat Methamphetamine Dependence in Men Who Have Sex With Men (MSM)
Status: COMPLETED
Conditions: Amphetamine-Related Disorders
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ribociclib and Bicalutamide in AR+ TNBC
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: ribociclib|DRUG: ribociclib|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Management in People With Spinal Cord Injury
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Spinal Cord Injuries
Interventions: DEVICE: Mandibular Advancement Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of QM1114-DP for the Treatment of Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: QM1114-DP|BIOLOGICAL: OnabotulinumtoxinA|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate and Metformin Insulin Sensitivity in Type 2 Diabetics Study
Status: TERMINATED
Conditions: Type 2 Diabetes|Dyslipidemia
Interventions: DRUG: Fenofibrate|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frailty and Sarcopenia Outcomes in Emergency General Surgery
Status: UNKNOWN
Conditions: Frail Elderly Syndrome|Emergencies|Surgery|Sarcopenia
Interventions: DIAGNOSTIC_TEST: CT abdomen +/- pelvis|DIAGNOSTIC_TEST: Edmunton Frailty Score|PROCEDURE: Emergency laparotomy for general surgical pathology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Milk Oligosaccharides and Childhood Diarrhoea
Status: COMPLETED
Conditions: Acute Diarrhea
Interventions: OTHER: Oral rehydration solution|OTHER: Zinc|OTHER: Human milk oligosaccharides|OTHER: Breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of the Timing of Postoperative Mobilisation After Locking Plate Osteosynthesis of Fractures of the Surgical Neck of the Humerus
Status: UNKNOWN
Conditions: Humeral Fracture
Interventions: PROCEDURE: Immediate mobilisation after locking-plate osteosynthesis|PROCEDURE: Standard mobilisation after locking plate osteosynthesis|DEVICE: Osteosynthesis with a locking plate (Philos)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Coronary Sinus Flow Reducer on Coronary Microcirculation and Myocardial Ischemia
Status: RECRUITING
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: DEVICE: Coronary Sinus Reducer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Uptake Chatbot for Eating Disorders
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Repeated Administration|BEHAVIORAL: Personalized Recommendation|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Core Modules Only|BEHAVIORAL: Motivational Interviewing, Personalized Recommendation, Repeated Administration|BEHAVIORAL: Motivational Interviewing, Repeated Administration|BEHAVIORAL: Motivational Interviewing, Personalized Recommendation|BEHAVIORAL: Personalized Recommendation, Repeated Administration|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Psychoeducation, Repeated Administration|BEHAVIORAL: Psychoeducation, Personalized Recommendation|BEHAVIORAL: Psychoeducation, Motivational Interviewing|BEHAVIORAL: Psychoeducation, Motivational Interviewing, Personalized Recommendation|BEHAVIORAL: Psychoeducation, Personalized Recommendation, Repeated Administration|BEHAVIORAL: Psychoeducation, Motivational Interviewing, Repeated Administration|BEHAVIORAL: Psychoeducation, Motivational Interviewing, Personalized Recommendation, Repeated Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Remediation of Autobiographical Memory in Schizophrenia Using SenseCam®
Status: UNKNOWN
Conditions: Schizophrenia Cognition Autobiographical Memory Cognitive Remediation
Interventions: DEVICE: Questionary|DEVICE: Questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Double Trigger in Patients With Low Number of Oocytes Retrieved Per Number of Preovulatory Follicles
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Double trigger|DRUG: HCG trigger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing In Vitro Fertilization Cycles
Status: COMPLETED
Conditions: Sperm Quality|Oligoasthenospermia
Interventions: DIETARY_SUPPLEMENT: myo-inositol + folic acid|DIETARY_SUPPLEMENT: myo-inositol + folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Emory Angioplasty Versus Surgery Trial (EAST)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: PROCEDURE: angioplasty, transluminal, percutaneous coronary|PROCEDURE: coronary artery bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: ESWL for Distal Ureteric Stone: Supine Versus Prone
Status: RECRUITING
Conditions: Urinary Tract Stones|Urinary Stones|Urinary Calculi
Interventions: PROCEDURE: Supine ESWL|PROCEDURE: Prone ESWL|DEVICE: Extracorporeal Shockwave Lithotripsy (ESWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Antibiotic Prophylaxis Using Co-trimoxazole to Prevent Spontaneous Bacterial Peritonitis in Cirrhosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Co-Trimoxazole 960Mg Dispersible Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial
Status: TERMINATED
Conditions: Heart Failure|Heart Failure Acute|Acute Cardiac Failure|Acute Cardiac Pulmonary Edema
Interventions: DRUG: Nitrates|DRUG: Loop Diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Liver Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Life Without Diabetes
Status: COMPLETED
Conditions: Prevention of Developing Type 2 Diabetes
Interventions: BEHAVIORAL: High intense interval training|BEHAVIORAL: Increased daily activity detected by the pedometer|BEHAVIORAL: Increased daily activity detected by the pedometer+HIIT|BEHAVIORAL: Increased daily activity detected by the pedometer+group intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury
Status: TERMINATED
Conditions: Acute Spinal Cord Injury
Interventions: OTHER: Hypotension avoidance|OTHER: Induced hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.
Status: RECRUITING
Conditions: Pain, Acute|Knee Osteoarthritis|Anesthesia
Interventions: DRUG: IPACK block with Bupivacaine 0.25% with adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: BIOLOGICAL: SHR-1210|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Plus Rituximab Followed by Lenalidomide Versus Rituximab Maintenance for Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Musculoskeletal Diseases|Joint Disease|Arthritis|Arthritis, Rheumatoid|Rheumatic Diseases|Connective Tissue Diseases|Autoimmune Diseases|Immune System Diseases
Interventions: BIOLOGICAL: tolerogenic dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy
Status: UNKNOWN
Conditions: Diabetic Neuropathy
Interventions: DRUG: placebo|DRUG: JWHGWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nocturnal Cyclic Enteral Nutrition Infusion Versus Continuous Infusion of Enteral Nutrition
Status: WITHDRAWN
Conditions: Critical Illness|Enteral Feeding Intolerance|Nutrition Support
Interventions: OTHER: Continuous enteral nutrition infusion|OTHER: Cyclic enteral nutrition infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Squamous Cell Carcinoma antigen2 in Verruca Vulgaris
Status: UNKNOWN
Conditions: Verruca Vulgaris|Healthy
Interventions: OTHER: Immunohistochemical staining monoclonal antibodies to SCCA2 (SERPINB4/ SCCA2 antibody)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Relapsed Refractory Multiple Myeloma
Interventions: DRUG: Elotuzumab, pomalidomide, dexamethasone|DRUG: Anti-LAG-3|DRUG: Anti-LAG-3 + Pomalidimide + Dexamethasone|DRUG: Anti-TIGIT|DRUG: Anti-TIGIT + Pomalidimide + Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Texan Allergy & Sinus Center Mountain Cedar Intra-Lymphatic Immunotherapy Study
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Tree Pollen|Allergic Conjunctivitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Intra-lymphatic allergenic extract|BIOLOGICAL: Intra-lymphatic placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TMS Treatment in Parkinson's Disease With Pain.
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation|Parkinson Disease|Pain
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease
Status: NOT_YET_RECRUITING
Conditions: Systemic Sclerosis With Lung Involvement|Systemic Sclerosis|Interstitial Lung Disease
Interventions: DRUG: Mycophenolate Mofetil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intra-Articular 0.5 % Lidocaine Injection for Osteoarthritis
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Families Moving Forward Website Behavioral Intervention for Teachers of Students With Fetal Alcohol Spectrum Disorder
Status: COMPLETED
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: BEHAVIORAL: Families Moving Forward (FMF) Teacher adapted training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chordate System Prophylactic Migraine Clinical Investigation
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Chordate System S200 + CT100 (active treatment)|DEVICE: Chordate System S200 + CT100 (placebo treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bariatric Surgery Versus Non-alcoholic Steato-hepatitis
Status: COMPLETED
Conditions: Non Alcoholic Steatohepatitis
Interventions: PROCEDURE: RYGB|PROCEDURE: SG|OTHER: Intensive Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of (WaterWorks®)Douching Device for Elimination of Perceived Vaginal Odor Not Caused by BV or Vaginitis
Status: UNKNOWN
Conditions: Vaginal Odor
Interventions: DEVICE: WaterWorks Douching Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study
Status: COMPLETED
Conditions: Bipolar Disorder|Mania|Bipolar Depression
Interventions: DRUG: taurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT