pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Artery Function Responses to Changes in Blood Flow
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: OTHER: Suprasystolic (300 mmHg) cuff compressions|OTHER: Handgrip exercise|OTHER: Passive heat stress
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: INCB099280
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin C and Zinc in Patients With Enterocutaneous Fistulas.
Status: RECRUITING
Conditions: Enterocutaneous Fistulas
Interventions: DRUG: Low-dose vitamin C and zinc|DRUG: High-dose vitamin C and zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanding Technology-Enabled Nurse Delivered Chronic Disease Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: BEHAVIORAL: EXTEND Plus|BEHAVIORAL: EXTEND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Research Study for Patients With Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Dapsone Gel, 5% for Treating Dermatitis Herpetiformis
Status: TERMINATED
Conditions: Dermatitis Herpetiformis
Interventions: DRUG: Dapsone gel, 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for Treatment of Antipsychotic-induced Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Isometric Handgrip Exercises on Blood Pressure of Hypertensive Adults
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: IHG|OTHER: Aerobic exercises|OTHER: Sham IHG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myfortic Versus Azathioprine in Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: switch to Myfortic|DRUG: continuation of azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Crizotinib for Rearrangement-negative, High Phosphorylated ALK Patients
Status: COMPLETED
Conditions: ALK Phosphorylation
Interventions: DRUG: crizotinib for rearrangement-negative, high phosphorylated ALK patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Electronic System to Improve Recovery Outcomes in Patients With Drug Use Disorder
Status: COMPLETED
Conditions: Drug Use Disorders|Addiction, Drug
Interventions: OTHER: Integrated rehabilitation group|OTHER: Community-based rehabilitation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ⅱ and Ⅲ Trial of a SARS-CoV-2 Vaccine LYB001
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: LYB001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease
Status: COMPLETED
Conditions: Biliary Tract Diseases|Gallbladder Diseases|Cholecystitis|Cholecystolithiasis
Interventions: PROCEDURE: Laparoscopic cholecystectomy|PROCEDURE: Small-incision open cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Planetary Health Diet Included in a Lifestyle Program in Overweight or Obese Mexican Adults.
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Planetary Health Diet Group|OTHER: Low-fat diet group|OTHER: Waiting list group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naldebain for Pain Management of Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Pain, Chronic|Cholecystitis|Quality of Life
Interventions: DRUG: Dinalbuphine sebacate|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment
Status: RECRUITING
Conditions: Opioid Use Disorder|Chronic Pain
Interventions: BEHAVIORAL: Steps 2 Change (S2C)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Theory-based Home-based Multi-component Exercise Training Among Older Adults With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2|Sarcopenia
Interventions: BEHAVIORAL: a theory-based home-based multi-component exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Isolated Limb Infusion Chemotherapy With Targeted Gene Therapy for Advanced, Unresectable Extremity Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: melphalan|BIOLOGICAL: Conditionally replicative adenovirus 3/5-delta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)
Status: RECRUITING
Conditions: Neoplastic Disease|Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: 131I-IPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing of Noonan Subjects Previously Treated With Norditropin®. An Extension to Trial GHNOO-1658
Status: COMPLETED
Conditions: Genetic Disorder|Noonan Syndrome
Interventions: DRUG: somatropin|DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine + Sufentanil|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cognitive Functions of Schizophrenic Patients Treated With Sertindole Versus Risperidone
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Sertindole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diquafosol Ophthalmic Solution for Dry Eye Symptoms
Status: NOT_YET_RECRUITING
Conditions: Diabetic Eye Problems
Interventions: DRUG: 3% Diquafosol tetrasodium|DRUG: 0.1% hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Capecitabine With Radiation in Elderly Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: capecitabine|DRUG: Capecitabine|DRUG: Capecitabine|DRUG: Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Assessment of Devices Used to Prevent Post-operative Hemorrhagic Risk in Endonasal Surgery
Status: COMPLETED
Conditions: Otorhinolaryngologic Diseases
Interventions: DEVICE: Surgiflo|DEVICE: Floseal|DEVICE: Algosteril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Fractional CO2 Laser Therapy for Survivors of Breast Malignancies
Status: COMPLETED
Conditions: Breast Carcinoma|Cancer Survivor|Cervical Carcinoma|Dyspareunia|Vaginal Dryness
Interventions: PROCEDURE: Laser Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Three Approaches to Address Fear of Recurrence Among Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer|Breast Carcinoma|Malignant Neoplasm of Breast|Cancer of Breast|Mammary Neoplasm, Human|Human Mammary Carcinoma|Malignant Tumor of Breast|Mammary Cancer|Mammary Carcinoma|Anxiety|Fear|Neoplasm Remission, Spontaneous|Spontaneous Neoplasm Regression|Regression, Spontaneous Neoplasm|Remission, Spontaneous Neoplasm|Spontaneous Neoplasm Remission
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Survivorship Education|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Panobinostat|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Vascular Disease|Pulmonary Artery Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: OTHER: 6-minute walk distance (6MWD) test|OTHER: 6-minute walk distance (6MWD) test with supplemental oxygen (3 l/min, nasal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Developing Psychological Resilience on Functionality in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive behavioral approach based resilience development program for schizophrenic individuals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gastric Acid Rebound Secretion Measured by Alkaline Tide
Status: WITHDRAWN
Conditions: Condition Measuring Alkaline Tide and Filling Symptoms' Questionnaire After Abrupt or Gradual Step Down Cessation of PPI
Interventions: DRUG: Stop PPI gradually|DRUG: Stop PPI gradually
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cooling Cap Trial to Prevent Permanent Chemotherapy-induced Alopecia in Breast Cancer Patients
Status: COMPLETED
Conditions: Neoplasm, Breast
Interventions: DEVICE: Scalp cooling system 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mothers Overcoming and Managing Stress
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|PTSD
Interventions: BEHAVIORAL: Trauma Affect Regulation: Guide for Education and Therapy|BEHAVIORAL: Present Centered Therapy (PCT) - psychotherapy|OTHER: No-treatment "waitlist" group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Basket Wires for the Maintenance of Stone and Pneumatic Probe in the Treatment of Ureteral Stones
Status: COMPLETED
Conditions: Ureter Stone
Interventions: DEVICE: Basket of wire|PROCEDURE: control group, no basket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Influence of Electromagnetic Field as an Adjunctive Non Surgical Treatment in Implant With Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Magdent Cap MED|DEVICE: Sham MED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Asunaprevir and Daclatasvir in Subjects Coinfected With HIV-HCV
Status: COMPLETED
Conditions: HIV-HCV
Interventions: DRUG: Asunaprevir and Daclatasvir|DRUG: Asunaprevir and Daclatasvir with BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: TAK-279|DRUG: Placebo|DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Locoregional Treatment With Immunotherapy for Unresectable HCC.
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatic Carcinoma
Interventions: DRUG: Sintilimab|PROCEDURE: Microwave Ablation|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)
Status: RECRUITING
Conditions: Tuberculosis|Pulmonary Tuberculosis|HIV Coinfection
Interventions: DRUG: Isoniazid|DRUG: Rifampicin|DRUG: Ethambutol|DRUG: Pyrazinamide|DRUG: Metformin hydrochoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G7 Freedom Constrained Vivacit-E Liners
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis, Hip|Rheumatoid Arthritis|Non-Union Fracture|Trochanteric Fractures|Femoral Neck Fractures|Avascular Necrosis|Dislocation, Hip
Interventions: DEVICE: Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Pediatric Palliative Care: Quality of Life & Spiritual Struggle
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: FAmily CEntered (FACE) ACP|BEHAVIORAL: Healthy Living Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of the Prognosis of Persistent Left Bundle Branch Block (LBBB)After Transcatheter Aortic Valve Implantation (TAVI ) by an Electrophysiological and Remote Monitoring Risk-adapted Algorithm
Status: UNKNOWN
Conditions: Post-TAVI
Interventions: OTHER: pacemaker implantation|OTHER: holter implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Transcranial Magnetic Stimulation (TMS) in the Treatment of Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: rTMS treatment using BrainsWay Model 104 system with H1-Coil|DEVICE: sham TMS using BrainsWay Model 104 system with H1-Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Psilocybin in Advanced-Stage Cancer Patients With Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Psilocybin (drug)|OTHER: Niacin|DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects on Glucose Regulation, Inflammation and Serum Lipids After Fish Protein Supplementation in Elderly (GRIPE)
Status: COMPLETED
Conditions: Muscle Weakness|Muscle Loss|Blood Sugar; High|Inflammation|Aging
Interventions: DIETARY_SUPPLEMENT: Blue whiting protein hydrolysate|DIETARY_SUPPLEMENT: Placebo Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Indirect Mechanism of Neuroprotection of Tecfidera® (Dimethyl Fumarate) in RRMS and Progressive Patients
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NDT on Fall Risk in Cerebral Palsied Children
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic|Falling
Interventions: OTHER: Neurodevelopmental Therapy (NDT)|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery
Status: RECRUITING
Conditions: Muscle Relaxation
Interventions: DRUG: MgSO4|DRUG: Rocuronium Bromide|DRUG: Cis-Atracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Endostar, Paclitaxel/Carboplatin and Radiotherapy for Locally Advanced Non-small Cell Lung (RT0902)
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Endostar|DRUG: Paclitaxel/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Drops in the Treatment of Subjects With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: OTX-TP|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EGb 761 in the Syndrome of MCI With Concomitant CVD
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Cerebrovascular Disease
Interventions: DRUG: Tebonin Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of TS-142 in Patients With Hepatic Impairment
Status: COMPLETED
Conditions: Patients With Mild or Moderate Hepatic Impairment
Interventions: DRUG: TS-142 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas
Status: RECRUITING
Conditions: Anal Fistula
Interventions: DEVICE: RD2 Ver.02|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Magnesium, Partenium, Andrographis, Co-enzyme Q10 and Riboflavin (PACR) in Migraine Prophylaxis
Status: UNKNOWN
Conditions: Migraine Disorders
Interventions: DIETARY_SUPPLEMENT: PACR|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: DRUG: parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Follow-up Study in Patients Previously Treated With a Mustang Bio CAR-T Cell Investigational Product.
Status: TERMINATED
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)|Chronic Lymphocytic Leukemia in Relapse|Small Lymphocytic Lymphoma, Relapsed|Waldenstrom's Macroglobulinemia Recurrent|Follicular B-cell Non-Hodgkin's Lymphoma|B-cell Lymphoma Refractory|Mantle Cell Lymphoma Recurrent|Hairy Cell Leukemia|Diffuse Large B Cell Lymphoma|Waldenstrom's Macroglobulinemia Refractory|Mantle Cell Lymphoma Refractory
Interventions: BIOLOGICAL: Prior MB-102 CAR-T cell investigational product.|BIOLOGICAL: Prior MB-106 CAR-T cell investigational product.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Wheeled Mobility in Everyday Life
Status: COMPLETED
Conditions: Chronic Heart Disorder|Lung Disorder|Arthritis
Interventions: OTHER: Wheeled Mobility in Everyday Life:Effects of Wheelchair Type on Mobility Performance of Elders in Public Environments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Pulmonary Hypertension Associated COPD With Inhaled Treprostinil-1
Status: COMPLETED
Conditions: Pulmonary Hypertension|COPD
Interventions: DRUG: Inhaled Treprostinil Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia
Status: COMPLETED
Conditions: Barrett Syndrome|Barrett's Syndrome|Barrett's Esophagus|Barrett Esophagus|Adenocarcinoma
Interventions: DEVICE: Standard endoscopic evaluation|DEVICE: pCLE guided evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Co-induction Technique Compared to Standard Inhalational and Intravenous Induction Techniques
Status: COMPLETED
Conditions: Anesthesia|Anesthesia; Adverse Effect
Interventions: DRUG: Induction using propofol|DRUG: Induction using sevoflurane|DRUG: Induction using propofol and sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Smart Sleep In-home Validation Extension Study
Status: COMPLETED
Conditions: Healthy|Sleep Deprivation|Insufficient Sleep Syndrome
Interventions: DEVICE: SmartSleep Boost On|DEVICE: SmartSleep Boost Off
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 Study
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balanced Anesthesia for Intubation of Premature Infants
Status: COMPLETED
Conditions: Premature Birth
Interventions: PROCEDURE: Tracheal intubation for respiratory care in preterm infants|PROCEDURE: Tracheal intubation for respiratory care in preterm infants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Triptorelin Pamoate in Children With Precocious Puberty - Follow up Study
Status: COMPLETED
Conditions: Precocious Puberty
Interventions: DRUG: Triptorelin (I.N.N.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Booster Vaccination Study With a Pneumococcal Vaccine in Children Primed With the Same Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: GSK Biologicals' Synflorix™ (Pneumococcal vaccine GSK1024850A)|BIOLOGICAL: Wyeth-Lederle's Prevenar™|BIOLOGICAL: GSK Biologicals' Hiberix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans
Status: RECRUITING
Conditions: Nonalcoholic Steatohepatitis|Liver Fibrosis
Interventions: DRUG: Synthroid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoimmunotherapy Study for Patients With Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Carboplatin|DRUG: GM-CSF (Sargramostim)|DRUG: Interferon Gamma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Tracking Devices to Locate Abnormalities During Invasive Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Adenocarcinoma|Prostate Neoplasms|Prostate Cancer|Renal Cell Carcinoma|Von Hippel Lindau Disease
Interventions: DEVICE: EM Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Stereotactic MRI-guided On-table Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: Stereotactic MRI-guided On-table Adaptive Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiological and Microscopic Evaluation of Atraumatic Restorative Treatment in Adult Dentition
Status: COMPLETED
Conditions: Dentin Caries|Infection
Interventions: PROCEDURE: Atraumatic restorative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy and Stereotactic Radiosurgery to Pancreatectomy for Patients With Borderline Resectable Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Chemotherapy|RADIATION: Stereotactic radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19
Status: WITHDRAWN
Conditions: COVID-19|Cytokine Storm|Acute Respiratory Distress Syndrome
Interventions: DRUG: DeltaRex-G
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma
Status: COMPLETED
Conditions: Solid Tumors|Virally Mediated Cancers and Liposarcoma
Interventions: DRUG: oral 5-azacitidine in combination with romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TAR Technique in the Treatment of Huge Abdominal Wall Hernia and Large Abdominal Wall Defect With or Without Botox Injection .
Status: UNKNOWN
Conditions: TAR Technique
Interventions: PROCEDURE: Tar with Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)
Status: RECRUITING
Conditions: COVID-19|Corona Virus Infection
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Recurrence Rate of Hepatocellular Carcinoma After Treatment of Chronic Hepatits C Patients With Direct Acting Antivirals: Randomized Controlled Phase 3 Trial
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Hepatitis C, Chronic
Interventions: DRUG: Administration of DAA-based treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab For Persistent Diabetic Macular Edema After Bevacizumab
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab 0.3mg/0.05cc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Effect of a Single Dose of Sotatercept (ACE-011) on Red Blood Cell Mass and Plasma Volume in Participants With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Sotatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of the Direct Pulp Capping in Primary Teeth
Status: COMPLETED
Conditions: Direct Pulp Capping|Pulpotomy|Primary Teeth
Interventions: PROCEDURE: direct pulp capping|PROCEDURE: pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switching From Tobramycin Inhalation Treatment to Tobramycin Inhaler Treatment: The Effect on CF Patients' Adherence and Quality of Life
Status: UNKNOWN
Conditions: Alteration in Quality of Life of CF Patients, Following Change of Treatment From Antibiotic Inhalation to Antibiotic Inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repetitive Transcranial Stimulation (rTMS) in Post Stroke Dysphagia
Status: COMPLETED
Conditions: Dysphagia|Stroke
Interventions: DEVICE: rTMS|DEVICE: Placebo rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standardization of Chortoglyphus Arcuatus Allergenic Extract. Determination of Biological Activity in HEP Units
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Conjunctivitis, Allergic
Interventions: OTHER: Standardization of allergenic extract (Ch. arcuatus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Role of Clean Intermittent Catheterization in Patients Undergoing Radiotherapy After Radical Hysterectomy for Cervical Cancer
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DEVICE: Clean Intermittent Catheterization|DEVICE: Indwelling catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Neurobiology of Approach Avoidance Training in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Approach-positive AAT|BEHAVIORAL: Control AAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation and Evaluation of a Fear of Cancer Recurrence Screening, Referral and Management Program
Status: NOT_YET_RECRUITING
Conditions: Fear of Cancer Recurrence|Cancer
Interventions: BEHAVIORAL: FCR screening and referral program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Treatment With mFOLFOXIRI Plus Cadonilimab (AK104) Versus mFOLFOX6 in Locally Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: mFOLFOXIRI + Cadonilimab|DRUG: mFOLFOX6|DRUG: mFOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Reperfusion Therapy
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Intravenous infusion of human albumin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Radiotherapy With or Without Adjuvant C/T in Advanced Stage Nasopharyngeal Carcinoma Patients
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cisplatin,5-FU,Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder
Interventions: DRUG: Simvastatin 20 mg|OTHER: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor in Combination With Thalidomide and Dexamethasone in RRMM
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Thalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Three Weekly Injections of a Bacterial-- Sourced Hyaluronate on Pain and Function in Patients With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Hyaluronate|Osteoarthritis|Knee
Interventions: PROCEDURE: Hya-Joint|PROCEDURE: Hyalgan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of HAT1 Compared to Calcipotriol in Patients With Mild to Moderate Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Psoriasis Vulgaris
Interventions: DRUG: HAT1 topical solution|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Intermittent cARdiac Electrical moNitorinG
Status: RECRUITING
Conditions: Torsades de Pointe Caused by Drug|Long QT Syndrome
Interventions: DEVICE: BodyGuardian Mini Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Daratumumab, Bortezomib, Dexamethasone, Pegylated Liposomal Doxorubicin Hydrochloride, and Lenalidomide in Treating Participants With Plasma Cell Leukemia
Status: WITHDRAWN
Conditions: Plasma Cell Leukemia
Interventions: DRUG: Bortezomib|BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of the Pharmacological Profile of the A2A Receptor to Adenosine in the Diagnosis of Myocardial Ischemia
Status: UNKNOWN
Conditions: Chronic Coronary Artery Disease
Interventions: BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Fixed Pramlintide:Insulin Dose Ratios on Postprandial Glucose in T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Pramlintide acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imaging Biomarkers of Lymphatic Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Lymphedema
Interventions: PROCEDURE: CDT with Negative Pressure|PROCEDURE: CDT alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metacognitive Therapy and Neuro-physiotherapy as a Treatment for Functional Movement Disorders
Status: RECRUITING
Conditions: Conversion Disorder
Interventions: OTHER: Neuro-physiotherapy|OTHER: Combination of metacognitive behavioral therapy and Neuro-physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Nicotine Replacement for Alcoholic Smokers
Status: COMPLETED
Conditions: Smoking|Alcoholism
Interventions: BEHAVIORAL: Cognitive Behavior Therapy for alcohol and smoking cessation|DRUG: Nicoderm CQ nicotine patch|DRUG: Placebo gum|DRUG: Nicotine gum - Nicorette®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Venous Stent System in the Treatment of Iliac Vein Stenosis or Occlusion
Status: COMPLETED
Conditions: Iliac Vein Stenosis|Iliac Vein Occlusion
Interventions: DEVICE: Zylox Peripheral Venous Stent|DEVICE: Zilver Vena Venous Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Diffuse Large B Cell Lymphoma|Follicular Lymphoma|Richter's Transformation
Interventions: DRUG: DTRM-555
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotational Stability of V4C Toric Implantable Contact Lenses After On Axis Implantation Measured With OPD Scan 3
Status: UNKNOWN
Conditions: Myopic Astigmatism
Interventions: PROCEDURE: V4c toric ICL implantation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PUFA Supplementation in Premature Infants
Status: COMPLETED
Conditions: Premature, Extremely Low Birth Weight Infants|Polyunsaturated Fatty Acid Levels
Interventions: DIETARY_SUPPLEMENT: LCPUFA supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Sofosbuvir With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant
Status: COMPLETED
Conditions: Hepatitis C|Hepatocellular Carcinoma
Interventions: DRUG: Sofosbuvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study
Status: UNKNOWN
Conditions: Relapsing-Remitting Multiple Sclerosis (RRMS)|Neuromyelitis Optica|Healthy
Interventions: PROCEDURE: Peripheral blood withdrawal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carboplatin and Bevacizumab for Recurrent Ependymoma
Status: COMPLETED
Conditions: Ependymoma|Anaplastic Ependymoma
Interventions: DRUG: Carboplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Left Bundle Branch Area Pacing for Patients With Permanent Atrial Fibrillation and Heart Failure
Status: RECRUITING
Conditions: Left Bundle Branch Area Pacing|Biventricular Pacing|Heart Failure|Permanent Atrial Fibrillation
Interventions: DEVICE: Left bundle branch area pacing|DEVICE: Biventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using "SDM With PDAs" to Help Infant Family to Decide the Third Primary Dosing Pneumococcal Conjugate Vaccine
Status: NOT_YET_RECRUITING
Conditions: Infants' Family Decide Baby's Vaccine
Interventions: OTHER: Patients Decision Aids (PDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Efficacy Study of rAvPAL-PEG Administered Daily in Subjects With Phenylketonuria (PKU)
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: rAvPAL-PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glue Application in the Treatment of Low-Output Fistulas
Status: UNKNOWN
Conditions: Low-output External Gastrointestinal Fistula
Interventions: PROCEDURE: Endoscopy exploration and glue application|PROCEDURE: Endoscopy exploration|DRUG: Antibiotics (ceftazidime, cefotaxime, or meropenem, with or without vancomycin)|DIETARY_SUPPLEMENT: Nutrition support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Dual Exercise and Lexiscan Positron Emission Tomography: IDEALPET
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Exercise plus Regadenoson (Lexercise)|DRUG: Regadenoson (Lexiscan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Exercise Intervention on Aging-related Motor Decline
Status: COMPLETED
Conditions: Aging|Exercise
Interventions: BEHAVIORAL: Stretching Exercise Intervention|BEHAVIORAL: Aerobic Exercise Intervention|BEHAVIORAL: Self Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Decitabine+BUCY vs BUCY Conditioning Regimen for MLL+ Acute Leukemia Undergoing Allo-HSCT
Status: UNKNOWN
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation|Conditions|Mixed-lineage-leukemia (MLL)-Rearranged Acute Leukemia
Interventions: DRUG: Decitabine|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Coping Skills Counseling for Problem Gambling and Trauma
Status: COMPLETED
Conditions: Gambling Disorder|Trauma, Psychological|Problem Gambling|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Seeking Safety|BEHAVIORAL: CBT for Pathological Gambling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Microcirculation-assisted Adjustment of Blood Flow of VA-ECMO on Prognosis
Status: COMPLETED
Conditions: Microcirculation|Extracorporeal Membrane Oxygenation
Interventions: DEVICE: Microcirculation examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reliability and Validity of a New Ankle Dorsiflexion Lunge Test Using a Level Laser.
Status: UNKNOWN
Conditions: Ankle Joint|Range of Motion, Articular|Reliability and Validity
Interventions: DIAGNOSTIC_TEST: level laser lunge test|DIAGNOSTIC_TEST: dorsiflexion Lunge test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Landmark-guided Compared to Ultrasound-guided Erector Spinae Plane Block Techniques for Analgesia in Female Patients After Breast Surgery.
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: Ultrasound-guided ESPB|PROCEDURE: Anatomical landmark-guided ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms
Status: RECRUITING
Conditions: Cancer|Solid Tumor|Thromboembolism|Cardiovascular Diseases|Immune System Diseases|Inflammatory Diseases|Colon Cancer|Breast Cancer|Prostate Cancer|Hepatocellular Carcinoma|Lung Cancer|Chemotherapy|Immunotherapy
Interventions: DRUG: Palbociclib|DRUG: Rivaroxaban|GENETIC: SNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Healthy Body, Healthy Bones After Bariatric Surgery Trial
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Bone Loss|Bone Resorption
Interventions: DRUG: Zoledronic Acid 5 mg/Bag 100 ml Inj|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION