pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Low Level Laser Therapy Versus Pulsed Ultrasound
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|POSTPARTUM CARPAL TUNNEL SYNDROME
Interventions: RADIATION: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Herbal Dietary Supplements on Aerobic Performance
Status: ENROLLING_BY_INVITATION
Conditions: Diet, Healthy
Interventions: COMBINATION_PRODUCT: Herbal Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%
Status: WITHDRAWN
Conditions: Post-menopausal Period
Interventions: DRUG: Testosterone gel 1% 2.2 mg|DRUG: Testosterone gel 1% 4.4 mg|DRUG: Testosterone gel 1% 8.8 mg|DRUG: Placebo of Testosterone Gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I, Pharmacokinetic, Pharmacodynamic Trial of PTK787 and Paclitaxel in Combination for Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasm Metastasis|Carcinoma
Interventions: DRUG: Paclitaxel plus PTK787
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection
Status: TERMINATED
Conditions: Sacro-Iliac Spondylosis
Interventions: DRUG: Dexamethasone|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sociodemographic, Psychological, and Quality of Life Factors on Dual-Task Performance in Elderly Iraqis
Status: COMPLETED
Conditions: Cognitive Dysfunction|Motor Skills Disorders|Aging
Interventions: OTHER: - Sociodemographic Assessment - Psychological Assessment - Quality of Life Assessment - D
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Direct Current Stimulation Associate to Constraint Induced Movement Therapy Over Premotor Cortex in Severe Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Cerebral Infarction
Interventions: DEVICE: Transcranial direct current stimulation|BEHAVIORAL: Constraint-Induced Movement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Paracetamol (1g x 4)|DRUG: Ibuprofen (400 mg x 4)|DRUG: Paracetamol (0,5 g x 4)|DRUG: Ibuprofen (200 mg x 4)|DRUG: Placebo (x4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Various Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood of Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: DRUG: single dose of vepdegestrant as tablet formulation (Treatment A)|DRUG: single dose of vepdegestrant as tablet formulation (Treatment B)|DRUG: single dose of vepdegestrant as tablet formulation (Treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Status: COMPLETED
Conditions: Patients With Locally Advanced Carcinoma of the Stomach and Oesophagogastric Junction
Interventions: RADIATION: CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of MRI-Guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids|Uterine Leiomyomata
Interventions: DEVICE: Philips MR guided HIFU system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Progestin on Frequent and/or Prolonged Bleeding With Nexplanon™
Status: TERMINATED
Conditions: Birth Control|Contraception|Implant|Breakthrough Bleeding|Uterine Bleeding
Interventions: DRUG: Norethindrone acetate (NTA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebellar Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Imaging Technique in Detecting Breast Microcalcifications in Patients Undergoing Biopsy for a Breast Abnormality
Status: COMPLETED
Conditions: Breast Carcinoma|Microcalcification
Interventions: DEVICE: Ultrasound|DEVICE: MicoPure ultrasound|PROCEDURE: Biopsy of Breast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Use of Ultra Rice Compared to Iron Drops Consumed by Anemic Children
Status: COMPLETED
Conditions: Anemia|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: iron fortified rice|DIETARY_SUPPLEMENT: iron drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|Esophageal Varices Bleeding|Gastric Variceal Bleeding|Bleeding
Interventions: BEHAVIORAL: re-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Attention-neuromuscular Training for Children With Developmental Coordination Disorder
Status: UNKNOWN
Conditions: Developmental Coordination Disorder
Interventions: OTHER: EEG biofeedback mental attention-neuromuscular training|OTHER: Neuromuscular training|OTHER: EEG biofeedback mental attention training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ADDE on Tear Interferometry
Status: COMPLETED
Conditions: Tear|Dry Eye Syndromes
Interventions: DRUG: 3% diquafosol eyedrops|PROCEDURE: Silicone punctal plug insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion
Status: UNKNOWN
Conditions: Dysphagia|Dysphonia|Postoperative Pain
Interventions: DRUG: Racemic Epinephrine|DRUG: Placebo (for racemic epinephrine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SCT1000 in Healthy Women Aged 18-45 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV InfectioN|HPV-Related Carcinoma
Interventions: BIOLOGICAL: Recombinant 14-Valent Human Papillomavirus Vaccine（Insect Cell）|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An ADME Study of [14C]AZD0780 in Healthy Male Subjects
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: AZD0780 tablet|DRUG: [14C]AZD0780 Solution for Infusion|DRUG: [14C]AZD0780 Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial of IVIG in Children With PANS
Status: UNKNOWN
Conditions: PANS Pediatric Acute-Onset Neuropsychiatric Syndrome
Interventions: DRUG: Privigen Injectable Product (Intravenous Immunoglobulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLASSIA Safety, Immunogenicity, and Bronchoalveolar Lavage Study
Status: COMPLETED
Conditions: Alpha1-antitrypsin Deficiency
Interventions: BIOLOGICAL: GLASSIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Heightened Levels of Aggression in Traumatized Offenders With Psychotherapeutic Means
Status: COMPLETED
Conditions: Appetitive Aggression
Interventions: BEHAVIORAL: FORNET (adapted version)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective HDAC6 Inhibitor ACY 241 in Combination With Nivolumab in Patients With Unresectable Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: ACY-241|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Tolerance of Caelyx in Patients With Epithelial Ovarian Cancer. (Study P04072)(COMPLETED)
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Pegylated Liposomal Doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib + Pomalidomide + Dexamethasone In MM
Status: RECRUITING
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse
Interventions: DRUG: Ixazomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarizotan in the Treatment of Neuroleptic-induced Tardive Dyskinesia
Status: TERMINATED
Conditions: Neuroleptic-induced Tardive Dyskinesia
Interventions: DRUG: Sarizotan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: a Flexible Wound Dressing for the Management of Genital Skin Conditions
Status: COMPLETED
Conditions: Vaginitis|Atrophic Vaginitis|Lichen Planus|Lichen Sclerosus|Menopause Related Conditions
Interventions: DEVICE: Film forming silicone gel (7-0940)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy
Status: RECRUITING
Conditions: Hypertension
Interventions: DRUG: LCZ|DRUG: LCZ/AML 200 mg/2.5 mg|DRUG: LCZ/AML 200 mg/5 mg|DRUG: LCZ/AML 200 mg/10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diffusion Tensor Imaging of the Median Nerve Before and After Carpal Tunnel Corticosteroid Injection in Patients With Carpal Tunnel Syndrome: Feasibility Study
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Magnetic resonance image (MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PK Study of Tacrolimus and Cyclosporine When Co-Administered With Adefovir Dipivoxil in Post-Liver Transplant Patients
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Adefovir Dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetic Profiles of LY03003 and Neupro
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: LY03003|DRUG: Neupro 4Mg/24Hr Transdermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3 Different Doses of IV Busulfan
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: BX2|DRUG: BX3|DRUG: BX4-Suspended
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial
Status: RECRUITING
Conditions: Advanced Breast Carcinoma|Advanced Colon Carcinoma|Advanced Colorectal Carcinoma|Advanced Endometrial Carcinoma|Advanced Gastric Carcinoma|Advanced Gastroesophageal Junction Adenocarcinoma|Advanced Malignant Solid Neoplasm|Advanced Salivary Gland Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|HER2-Positive Breast Carcinoma|Malignant Hepatobiliary Neoplasm|Metastatic Breast Carcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Metastatic Malignant Solid Neoplasm|Stage III Colon Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Major Salivary Gland Cancer AJCC v8|Stage III Uterine Corpus Cancer AJCC v8|Stage IV Colon Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Major Salivary Gland Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Unresectable Colorectal Carcinoma|Unresectable Gastroesophageal Junction Adenocarcinoma|Unresectable Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Ceralasertib|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ligation of Intersphincteric Fistula Tract Versus Rectal Advancement Flap in the Treatment of Complex Anal Fistula
Status: UNKNOWN
Conditions: Anal Fistula
Interventions: PROCEDURE: LIFT|PROCEDURE: FLAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Onlay Mesh Hernioplasty Vs Sublay Mesh Hernioplasty for Paraumbilical Hernia Repair
Status: COMPLETED
Conditions: Paraumbilical Hernia
Interventions: PROCEDURE: Onlay mesh Hernioplasty|PROCEDURE: Sublay Mesh Hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Balance in CKD
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic|Kidney Failure, Chronic
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Matrix Efficacy for Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Sinus; Dental
Interventions: PROCEDURE: Maxillary Sinus Augmentation|PROCEDURE: Maxillary Sinus Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Ocular Surface Disease Assessment Between BRIDIN-T Eye Drops 0.15% and ALPHAGAN-P Eye Drops 0.15% in Glaucoma or Ocular Hypertensive Patients : Phase 4, Parallel Group Design, Investigator-blind, Active-control, Randomized, Multi-center Trial
Status: UNKNOWN
Conditions: Glaucoma|Ocular Hypertensive
Interventions: DRUG: Brimonidine Tartrate 1.5mg|DRUG: Brimonidine Tartrate 1.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise in Obesity for Health and Quality of Life.
Status: COMPLETED
Conditions: Obesity|Overweight and Obesity|Overweight or Obesity
Interventions: BEHAVIORAL: exercise training program|BEHAVIORAL: Feeding training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the inHaled Recombinant COVID-19 Vaccine (Adenovirus Type 5 Vector) On the Protective-Efficacy in Adults (SeiHOPE)
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Training on Hemodynamic Factors in Ballet Dancer
Status: COMPLETED
Conditions: Venous Insufficiency|Foot Drop (Acquired)
Interventions: OTHER: Navicular drop measurement|OTHER: Measurement of venous return parameters in supine|OTHER: Measurement of venous return parameters in standing|OTHER: measurement of midfoot pressure distrubition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Dichloroacetate Toxicity
Status: COMPLETED
Conditions: Acidosis, Lactic|Chronic Disease
Interventions: DRUG: Nitisinone (NTBC)|DRUG: Dichloroacetate|BEHAVIORAL: Low-tyrosin diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Online Visit Compared With In-person Clinic Visit on Weight Loss
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: online visit group|BEHAVIORAL: Clinic visit group|BEHAVIORAL: self-directed group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serial OCT Evaluation of Tissue Coverage in Patients Submitted to Inspiron Drug Eluting Stent Implantation
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Angiography and Optical Coherence Tomography evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Individualised and Patient-centred Follow-up Program for Women With Gynaecological Cancer
Status: RECRUITING
Conditions: Empowerment, Cervical Cancer, Endometrial Cancer, Follow-up, Nurse-led, PROM
Interventions: BEHAVIORAL: NEMO: NEw MOdel of follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Growth Hormone on Leptin, Cytokines and Body Composition of Children With Growth Failure Due to Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Recombinant Human Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Re-Irradiation in Thoracic Cancers
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Lung|Recurrent Disease|Thoracic Neoplasm
Interventions: RADIATION: Proton Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Relapse & HIV Risk: 48 Versus 24 Weeks of Injectable Extended Release Naltrexone
Status: COMPLETED
Conditions: Opiate Dependence|Human Immunodeficiency Virus
Interventions: DRUG: injectable naltrexone|DRUG: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Furosemide for Accelerated Recovery of Blood Pressure Postpartum
Status: COMPLETED
Conditions: Hypertension, Pregnancy-Induced
Interventions: DRUG: Oral furosemide|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carnitine for the Treatment of Atherosclerosis.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: L-carnitine capsules|DIETARY_SUPPLEMENT: Cellulose capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Irreversible Myocardial Injury in Cardiomyopathies by Contrast-enhanced CMR
Status: COMPLETED
Conditions: Cardiomyopathy, Dilated|Cardiomyopathies, Secondary
Interventions: PROCEDURE: Cardiac Magnetic Resonance study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunomodulatory Properties of Ketamine in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Ketamine|DRUG: Normal Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Ibrutinib Combined With Nivolumab or Cetuximab to Treat Recurrent/Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Ibrutinib 560mg PO daily (Imbruvica)|DRUG: Cetuximab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant IBI308, Bevacizumab, Plus Pemetrexed and Carboplatin Followed by Surgery in Unresectable Stage III NSCLC
Status: RECRUITING
Conditions: Lung Cancer Stage III
Interventions: DRUG: IBI308|DRUG: Bevacizumab|DRUG: Pemetrexed|DRUG: Carboplatin|PROCEDURE: Thoracic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|B Acute Lymphoblastic Leukemia|Recurrent B Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of SM04755 in Subjects With Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Gastric Cancer|Hepatic Cancer|Pancreatic Cancer
Interventions: DRUG: SM04755
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Anticancer Medication Combined With Immune Cells in Subjects With Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Gastrointestinal Cancer
Interventions: BIOLOGICAL: anticancer medication A01; immune cells IC01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
Status: COMPLETED
Conditions: Hemifacial Spasm|Microvascular Decompression|Lateral Spread Response Monitoring
Interventions: OTHER: TOF count-guided partial NMB|OTHER: T1/Tc guided partial NMB|OTHER: No NMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C]-BI 207127 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 207127 NA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Naldebain for Pain Control After Bariatric Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Pain, Chronic|Bariatric Surgery|Obesity|Pharmacokinetics
Interventions: DRUG: Dinalbuphine sebacate|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantification of DNA Repair Products in the Urine After Ultraviolet Radiation of the Skin
Status: ACTIVE_NOT_RECRUITING
Conditions: Ultraviolet Rays; Injury|DNA Adduct Formation|DNA Damage, Radiation Induced|DNA Damage
Interventions: RADIATION: Ultraviolet radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIR 561 CL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of L-FMAU in Chronic HBV Patients of L-FMAU-201 Placebo Group
Status: TERMINATED
Conditions: Hepatitis B
Interventions: DRUG: Clevudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline in Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: pentoxifylline (PTX)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sub-study of Cabotegravir (CAB) and Rilpivirine (RPV) in Human Immunodeficiency Viruses (HIV)-Infected Participants
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1 (HIV-1)
Interventions: DRUG: Cabotegravir Injectable Suspension|DRUG: Rilpivirine Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Malignant Glioma
Interventions: DRUG: Sym004 - 18 mg/kg|DRUG: Sym004 - 24 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inferior Vena Cava Diameter Dependent Colloid Challenge Versus Routine Crystalloid Strategy Transurethral Resection Prostate
Status: COMPLETED
Conditions: Volume Overload
Interventions: OTHER: Ultrasound-guided Inferior vena cava diameter dependent colloid challenge versus routine crystalloid strategy Fluid replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Broad Implementation of Outpatient Stewardship
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Respiratory Tract Infection|Otitis Media|Pharyngitis|Acute Sinusitis
Interventions: BEHAVIORAL: Broad Implementation of Outpatient Stewardship (BIOS) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hematopoietic Stem Cell Transplantation From Human Leukocyte Antigen (HLA) Compatible Donor in Ewing Sarcomas and Soft Tissues Sarcomas
Status: UNKNOWN
Conditions: Ewing|Soft Tissue Sarcoma
Interventions: PROCEDURE: Allogeneic hemopoietic stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies
Status: TERMINATED
Conditions: Hepatocellular Carcinoma (HCC)|Cholangiocarcinoma|Esophageal Cancer|Nasopharyngeal Cancer|Ovarian Cancer|Solid Tumors
Interventions: DRUG: INCB062079
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals
Status: RECRUITING
Conditions: Early-Onset Scoliosis Deformity of Spine
Interventions: DEVICE: MAGEC® Spinal Bracing And Distraction System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Almonertinib as First-line Treatment in Patients With EGFR+ Positive Pulmonary Adenosquamous Carcinoma or Combined Adenocarcinoma and Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Pulmonary Adenosquamous Carcinoma
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|PD-L1 Negative
Interventions: DRUG: Sacituzumab Govitecan|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Asthma in School-age Children on Therapy
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: inhaled fluticasone propionate|DRUG: salmeterol|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vale+Tú Salud: Corner-Based Randomized Trial to Test a Latino Day Laborer Program Adapted to Prevent COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BEHAVIORAL: COVID-19 Group Problem Solving|BEHAVIORAL: Standard of Care|BEHAVIORAL: Booster session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PRT for Adolescents With High Functioning Autism
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder High-Functioning|Developmental Disability|Child Development|Behavior, Child|Behavior, Social
Interventions: BEHAVIORAL: PRT for Adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensory Integration of Auditory and Visual Cues in Diverse Contexts
Status: ACTIVE_NOT_RECRUITING
Conditions: Vestibular Disorder|Hearing Loss, Sensorineural
Interventions: BEHAVIORAL: Visual and Auditory Cues
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Intermittent Versus Continuous Energy Restriction on Metabolic Adaptation in Women With Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: Intermittent energy restriction (IER)|BEHAVIORAL: Continuous energy restriction (CER)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Ascending Doses of REL-1017 (d-Methadone)
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: REL-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Nifedipine Controlled-Release Tablets (Xin Ran) to Treat Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: nifedipine CR tablets (Xin Ran)|DRUG: nifedipine CR tablets (Adalat)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Tibial Osteotomy for Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Opening-wedge HTO|PROCEDURE: Closing-wedge HTO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-Frequency In Situ Simulation-based Team Training on Clinical Performance During Pediatric Cardiac Arrest
Status: COMPLETED
Conditions: Medical Education|Simulation-based Training|In-hospital Cardiac Arrest|Pediatrics|in Situ Simulation
Interventions: OTHER: High-frequency simulation-based team training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement
Status: ACTIVE_NOT_RECRUITING
Conditions: Rate of Canine Retraction|Root Resorption
Interventions: PROCEDURE: Injectable platelet rich fibrin|DEVICE: Low Level LASER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interest of the T2 * Sequence in MRI for the Diagnosis of Migraine Aura in the Acute Phase.
Status: COMPLETED
Conditions: Migraine Aura
Interventions: COMBINATION_PRODUCT: MRI|DIAGNOSTIC_TEST: MRI control|OTHER: telephone consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL in HIV+ Subjects
Status: COMPLETED
Conditions: HIV Infections|Metabolism, Lipids
Interventions: DRUG: nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: A Study to Compare the Efficacy and Safety of Different Dosings of Olodaterol Administered With the Respimat® Inhaler in Patients With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo twice daily|DRUG: Olodaterol low daily dose twice daily|DRUG: Olodaterol medium daily dose twice daily|DRUG: Placebo twice daily|DRUG: Olodaterol high daily dose once daily and placebo|DRUG: Olodaterol medium daily dose once daily and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Online Psychological Care Program for Women Who Attend a Breast Clinic.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Online psychological care program to reduce psychological distress in women who attend a breast clinic|BEHAVIORAL: Psychological care program to reduce psychological distress in women who attend a breast clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial of Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthritis|Total Hip Arthroplasty (THA)
Interventions: PROCEDURE: Total Hip Arthroplasty|PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Tolerability of Ceradan Advanced Cream in the Treatment of Children With Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis Eczema
Interventions: DEVICE: Ceradan ® Advanced Cream|DEVICE: Basic cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems
Status: COMPLETED
Conditions: Healthy|Hepatic Insufficiency
Interventions: DRUG: BI 685509|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance
Status: NOT_YET_RECRUITING
Conditions: Postoperative Sleep Disturbance
Interventions: DRUG: Normal Saline|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: PrimeC-ER 748 mg|DRUG: Ciprofloxacin 750 MG|DRUG: Celecoxib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Deleterious BRCA1 Gene Mutation|Deleterious BRCA2 Gene Mutation|Endometrial Adenocarcinoma|High Grade Ovarian Serous Adenocarcinoma|Platinum-Resistant Ovarian Carcinoma|Primary Peritoneal High Grade Serous Adenocarcinoma|Progressive Disease|Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Copanlisib|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.
Status: RECRUITING
Conditions: Toxic Optic Neuropathy|Treatment|Methylprednisolone|Erythropoietin
Interventions: DRUG: Recombinant human erythropoietin 4,000 UI and 2,000 UI|DRUG: Methylprednisolone succinate 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides
Status: RECRUITING
Conditions: Localized Skin Lesion|Mycosis Fungoides
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Inflammation on Micronutrient Status Assessment
Status: COMPLETED
Conditions: Healthy Infants
Interventions: BIOLOGICAL: Pentavalent vaccine. It is a combination of five different antigens (Hepatitis B (HBV)/ Haemophilus influenzae type b (HiB) / Tetanus-Diphtheria-whole cell Pertussis (TDwP)).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate Belimumab for the Treatment of Chronic Immune Thrombocytopenia.
Status: WITHDRAWN
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: Belimumab|DRUG: Normal saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Clinical Study of CAR-T Cells Treatment for Children With CD19+/CD22+ R/R ALL and Lymphoma
Status: RECRUITING
Conditions: Relapsed B-cell Acute Lymphoblastic Leukemia, Childhood|Refractory B-cell Acute Lymphoblastic Leukemia, Childhood|Relapsed/Refractory B-cell Lymphoma, Childhood
Interventions: BIOLOGICAL: CAR-T19/CAR-T22
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descemet Endothelial Thickness Comparison Trial I
Status: RECRUITING
Conditions: Fuchs
Interventions: DRUG: Topical Ripasudil|DRUG: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipatasertib + Pertuzumab +Trastuzumab in Advanced HER2+ PI3KCA-mutant Breast Cancer Patients
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Ipatasertib|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Inhaled Laninamivir Octanoate TwinCaps® DPI in Adults With Chronic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Laninamivir octanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Advanced Melanoma (MK-3475-041/KEYNOTE-041)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multidimensional Lifestyle Intervention to Reduce the Risk of Metabolic Disorders in Older Workers in Taiwan
Status: COMPLETED
Conditions: Metabolic Disorder
Interventions: BEHAVIORAL: Multidimensional lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dissemination and Implementation of a Videoconference Antimicrobial Stewardship Team
Status: ACTIVE_NOT_RECRUITING
Conditions: Common Infections|Urinary Tract Infections|Pneumonia
Interventions: OTHER: Antibiotic Use Report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Beta-blockers on Physical Function in HFpEF
Status: COMPLETED
Conditions: Heart Failure|Heart Failure, Diastolic|Heart Failure With Preserved Ejection Fraction|Cardiac Failure|Heart Disease
Interventions: DRUG: Beta blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carboxyamidotriazole in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboxyamidotriazole|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Stopping Risedronate After Long Term Treatment on Bone Turnover
Status: COMPLETED
Conditions: Postmenopausal Women With Osteoporosis
Interventions: DRUG: Risedronate|DRUG: Placebo/Risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Incisions and Wound Complication Rates for C-sections in Obese Women
Status: UNKNOWN
Conditions: Obesity|Infection; Cesarean Section|Surgical Wound
Interventions: PROCEDURE: Midline Vertical|PROCEDURE: High Transverse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PEEK Versus Titanium Customized Healing Abutments
Status: RECRUITING
Conditions: Dental Implants
Interventions: DEVICE: PEEK customized healing abutment|DEVICE: Titanium customized healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Yong Chong Cao Capsule on Outcomes in Patients With Mild to Severe COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salbutamol (Ventolin®)|DRUG: Tiotropium Bromide (Spiriva®)|DRUG: Salmeterol / fluticasone (Seretide®)|DRUG: YCC capsule|DRUG: BL capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 48 Weeks Combination Therapy for Patients With HBeAg-negative Chronic Hepatitis B Virus (HBV) Infection
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Ribavirin|DRUG: Peginterferon alpha 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Thiamine Deficiency|Congenital Heart Disease|Cardiopulmonary Bypass
Interventions: DRUG: Neurobion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block
Status: COMPLETED
Conditions: Injury of Upper Limb
Interventions: DRUG: ropivacaine|DRUG: ropivacaine mixed with dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT