pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Guided Internet-based Trauma-focused CBT Programme for Post-traumatic Stress Disorder 'Spring'
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Internet-based guided programme Spring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Antagonist Drugs of the Cellular Transcriptomic Signature of Influenza A Virus Infection.
Status: TERMINATED
Conditions: Flu
Interventions: DRUG: Oseltamivir|DRUG: Diltiazem|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan
Status: COMPLETED
Conditions: Hereditary Angioedema, HAE
Interventions: DRUG: BCX7353 capsules|DRUG: BCX7353 capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-Guided Hydrodilatation With Triamcinolone Acetonide for Adhesive Capsulitis
Status: RECRUITING
Conditions: Postoperation Pain
Interventions: PROCEDURE: Ultrasound-Guided Hydrodilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Examining the Safety and Effectiveness of a New Medication (Keppra®) for the Prevention of Migraine Headaches
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: levetiracetam|PROCEDURE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With Tumor mRNA in Metastatic Melanoma - Fixed Combination Versus Individual Selection of Targeted Antigens
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: BIOLOGICAL: mRNA coding for melanoma associated antigens|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Xenin-25 on Insulin Secretion and Gastric Emptying in Humans With and Without a Complete Truncal Vagotomy
Status: WITHDRAWN
Conditions: Does the Vagus Nerve Mediate the Effects of Xenin-25
Interventions: DRUG: Graded Glucose Infusion with Placebo|DRUG: Graded Glucose Infusion with GIP Alone|DRUG: Graded Glucose Infusion with xenin-25 alone|DRUG: Graded Glucose Infusion with GIP plus xenin-25|DRUG: Meal Tolerance Test with Placebo|DRUG: Meal Tolerance Test with xenin-25
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older
Status: RECRUITING
Conditions: DLBCL
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Preterm Births in Underserved Pregnant Women
Status: COMPLETED
Conditions: Preterm Birth|Low Birth Weight <2500 Grams|Verylow Birthweight <1500 Grams
Interventions: BEHAVIORAL: lifestyle support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transversus Abdominis Plane Block (TAP) for Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic|Pain, Postoperative
Interventions: DRUG: Levobupivacaine 0.25 %|DRUG: Levobupivacaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dietary Intervention on Gastrointestinal Function in Patients With Anorexia Nervosa and Obesity
Status: COMPLETED
Conditions: Anorexia Nervosa|Obesity|Healthy Participants
Interventions: BEHAVIORAL: Nutritional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)
Status: UNKNOWN
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Y peginterferon alfa-2b|DRUG: Granulocyte-macrophage colony stimulating factor|DRUG: Entecavir and or adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity Study of Antibody Persistence and Booster Effect of PENTAXIM™ at 18 Months in Healthy Argentinean Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis|Hepatitis B
Interventions: BIOLOGICAL: DTaP-IPV//PRP~T combined vaccine|BIOLOGICAL: DTaP-IPV//PRP~T combined vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy, and Tolerability of NBI-827104 for the Treatment of Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: NBI-827104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Liposomal Doxorubicin Combined With Ifosfamide Second-line Treatment in Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DEVICE: Liposomal Doxorubicin Combined With ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine as an Adjuvant Analgesic for Third Molar Surgery
Status: COMPLETED
Conditions: Dental Crowding
Interventions: DRUG: Nicotine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Online Psychosocial Intervention for Fear of Cancer Recurrence in Breast Cancer Survivors
Status: RECRUITING
Conditions: Fear of Cancer Recurrence|Breast Cancer
Interventions: BEHAVIORAL: Online mindfulness and acceptance intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sodium-glucose Co-transporter 2 Inhibitors Effects in Failing Heart Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Heart Failure|Ventricular Arrythmia
Interventions: DRUG: SLGT2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Non-heme Iron Absorption From Single Meals of Fava Bean Protein, Beef Protein and Cod Protein
Status: COMPLETED
Conditions: Healthy|Nutrition, Healthy
Interventions: OTHER: Single meal non-heme iron absorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Prolonged Exposure for Post Traumatic Stress Disorder (PTSD) Among Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) Personnel
Status: COMPLETED
Conditions: Posttraumatic Stress Disorders|Combat Disorders
Interventions: BEHAVIORAL: Prolonged Exposure Therapy - Massed|BEHAVIORAL: Prolonged Exposure Therapy - Spaced|BEHAVIORAL: Minimal Contact Control|BEHAVIORAL: Present-Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Radiation Therapy, and Prednisone in Treating Patients Who Have Undergone Surgery For Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: prednisone|PROCEDURE: Radical prostatectomy|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunologic Basis of Anti-IgE Therapy (Study II: On Patients With Asthma)
Status: COMPLETED
Conditions: Asthma|Allergic Rhinitis|Atopic Dermatitis
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Effort Driven VENTilator Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventilation Therapy; Complications|Diaphragm Disease|Pediatric Respiratory Diseases
Interventions: OTHER: Computerized Ventilator Protocol|DIAGNOSTIC_TEST: Esophageal Manometry|DIAGNOSTIC_TEST: Respiratory Inductance Plethysmography (RIP)|DIAGNOSTIC_TEST: Diaphragm Ultrasound|DIAGNOSTIC_TEST: Maximal Inspiratory Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Follow-up of Glypressin (Terlipressin) Clinical Efficacy in the Treatment of Bleeding Oesophageal Varices
Status: COMPLETED
Conditions: Gastrointestinal Bleeding|Oesophageal Varices
Interventions: OTHER: Glypressin (terlipressin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance of Dentals Implants With Hydrophilic or Hydrophobic Surfaces
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Loss
Interventions: DEVICE: Hydrophilic surface implants|DEVICE: Hydrophobic surface implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antaitavir Hasophate Capsules Combined With Yiqibuvir Tablets in Treatment Adult Patients With Chronic Hepatitis C
Status: UNKNOWN
Conditions: Chronic HCV Infection
Interventions: DRUG: HEC74647PA+HEC110114|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for Osteomyelitis
Status: TERMINATED
Conditions: Osteomyelitis
Interventions: DRUG: Intravenous Antibacterial Agent|DRUG: Oral Antibacterial Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Ascending Dose Study of JK07 in Subjects With HFpEF
Status: WITHDRAWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: JK07|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque
Status: RECRUITING
Conditions: Inflammation|Atheromatous Plaques|Carotid Artery Diseases
Interventions: DRUG: 68Ga-NODAGA-RGD PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of the PRO-174 Versus Sophixín Ofteno®, on the Ocular Surface of Healthy Subjects
Status: COMPLETED
Conditions: Conjunctivitis|Conjunctivitis, Bacterial
Interventions: DRUG: PRO-174|DRUG: Sophixín Ofteno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma|Locally Advanced Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: PROCEDURE: Biopsy|DRUG: Osimertinib|DRUG: Triptolide Analog
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of Carbetocin Given During Elective Cesarean
Status: COMPLETED
Conditions: Effect of Carbetocin on Cardiovascular System|Pregnancy
Interventions: DRUG: carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Bundle-size 1|BEHAVIORAL: Bundle-size 3|BEHAVIORAL: Bundle-size 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Double-blind, Placebo-Controlled Divalproex Sodium ER in Bipolar I or Bipolar II Depression
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Divalproex Sodium ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine
Status: RECRUITING
Conditions: Pneumococcal Infectious Disease
Interventions: BIOLOGICAL: Sinovac PCV13|BIOLOGICAL: PREVNAR 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Texting and Writing on Grip and Pinch Strength
Status: COMPLETED
Conditions: Muscle Weakness Condition|Hand Grasp
Interventions: OTHER: Texting- 10 minutes|OTHER: Writing- 10 minutes|OTHER: Texting- 15 minutes|OTHER: Writing- 15 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency and Safety Study of Pamidronate in Inflammatory Back Pain Due to Degenerative Disk Disease
Status: UNKNOWN
Conditions: Intervertebral Disc Degeneration|Modic I Discopathy|Back Pain|Low Back Pain|Magnetic Resonance Imaging (MRI)
Interventions: DRUG: Pamidronate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sealants in Molars Affected by Molar-Incisor Hypomineralization
Status: COMPLETED
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: Conventional Sealants|PROCEDURE: Resin Sealants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Glucosestimulation After Gastric Bypass Surgery
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: 25g of glucose in 200ml tap water, given orally (plus 50 mg 13C-sodium acetate)|DIETARY_SUPPLEMENT: 10g Glucose in 200ml tap water given orally (plus 50 mg 13C-sodium acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Testing the Bioavailability of Phytonutrients, Curcumin and Ursolic Acid
Status: COMPLETED
Conditions: Bioavailability of Phytonutrients
Interventions: DRUG: Ursolic Acid|DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Dabigatran etexilate|DRUG: Midazolam|DRUG: BAY1841788 (darolutamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Denosumab for the Treatment of Osteoporosis in Children: A Pilot Study
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Zoledronic Acid|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction
Status: COMPLETED
Conditions: Small Bowel Obstruction
Interventions: DRUG: gastrograffin|DRUG: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Immuncell-LC Group and Non-treatment Group in Hepatocelluar Carcinoma Patients
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Immuncell-LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: SHAM - Intermittent Room Air - room air mixture|OTHER: AIH - Intermittent Hypoxia - hypoxia air mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
Status: UNKNOWN
Conditions: Anxiety Acute|Anxiety Fear|Peri-operative|Psychological Distress|Surgery|Children, Only
Interventions: DEVICE: Little Journey app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Axio Scapular Muscle Stretching Exercises in Office Workers
Status: COMPLETED
Conditions: Neck Muscle Issue
Interventions: OTHER: High frequency of stretching exercise|OTHER: Low frequency of stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E. Coli 83972 Induced Asymptomatic Bacteriuria (ABU) in Patients With Recurrent Urinary Tract Infections (UTI)
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: BIOLOGICAL: E. coli 83972
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Turoctocog Alfa Pegol (N8-GP) for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Chinese Patients With Haemophilia A (pathfinder10)
Status: COMPLETED
Conditions: Haemophilia A
Interventions: DRUG: turoctocog alfa pegol (N8-GP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma
Status: COMPLETED
Conditions: Central Nervous System Tumors|Brain Tumor
Interventions: DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in ad Hoc Percutaneous Coronary Interventions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EEG-based Sedation Protocol for Patients on Mechanical Ventilation Due to SARS-CoV-2 Pneumonia
Status: COMPLETED
Conditions: Sedation Complication|Covid19
Interventions: OTHER: EEG based protocol for deep sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Regional Myocardial Dynamics at Physical Stress in Essential Hypertension
Status: COMPLETED
Conditions: Hypertension|Left Ventricular Hypertrophy
Interventions: PROCEDURE: stress echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Interferon Gamma in Treating Patients With Recurrent or Metastatic Melanoma or Other Solid Tumors
Status: COMPLETED
Conditions: Melanoma (Skin)|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: recombinant interferon gamma
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acceptance-Based Separated Family Treatment for Adolescent Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Subthreshold Anorexia Nervosa|Eating Disorder Not Otherwise Specified, Primary Restriction
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Parent Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Naltrexone for Bladder Pain Syndrome
Status: SUSPENDED
Conditions: Bladder Pain Syndrome|Interstitial Cystitis
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of High Resolution EEG Functional Connectivity Measures to Presurgical Evaluation of Patients With Intractable Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: PROCEDURE: Electroencephalography|PROCEDURE: Electroencephalography and additional experimental tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
Status: NOT_YET_RECRUITING
Conditions: Migraine
Interventions: DRUG: Topiramate|DRUG: Flunarizine|DRUG: Amitriptyline|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Canadian Maraviroc Randomized Controlled Trial To Augment Rehabilitation Outcomes After Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DRUG: Maraviroc|BEHAVIORAL: Exercise Program|OTHER: Placebo|DEVICE: Activity Sensor|BEHAVIORAL: Motor Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Video-assisted Lobectomy/Segmentectomy for Lung Surgery
Status: RECRUITING
Conditions: Lung Diseases|Surgery
Interventions: PROCEDURE: robotic surgery|PROCEDURE: uniport surgery|PROCEDURE: multiple- port surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Intramuscular Gene Transfer Trial of rAAVrh74.MCK.Micro-Dystrophin to Patients With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: rAAVrh74.MCK.micro-Dystrophin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide and Rituximab in Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia|Lymphoplasmacytic Lymphoma
Interventions: DRUG: Thalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)
Status: NOT_YET_RECRUITING
Conditions: Sexually Transmitted Infections (Not HIV or Hepatitis)|HIV Infections|Sexual Behavior
Interventions: BEHAVIORAL: IMARA for Black Male Caregivers and Girls Empowerment|BEHAVIORAL: Time-matched control program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors
Status: RECRUITING
Conditions: Neoplasms|Solid Tumors
Interventions: DRUG: aza-TdC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Ovarian Cancer|Fallopian Tube Cancer|Triple Negative Breast Cancer|Multiple Myeloma|Pancreatic Ductal Adenocarcinoma
Interventions: BIOLOGICAL: CART-TnMUC1|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Daratumumab to Overcome Platelet Transfusion Refractoriness in Patients With Aplastic Anemia
Status: RECRUITING
Conditions: Aplastic Anemia|Platelet Transfusion Refractoriness
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial to Investigate Whether Self Ligating Brackets or Conventional Brackets Are Better for Treating Bimaxillary Proclination
Status: UNKNOWN
Conditions: Bimaxillary Proclination
Interventions: OTHER: Orthodontic Brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIBW 2992 (Afatinib) and Vinorelbine in Japanese Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: afatinib 20mg|DRUG: afatinib 40mg|DRUG: vinorelbine IV 25 or 20mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority of Lower Dose Calcium Supplementation During Pregnancy
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Daily 500 mg elemental calcium as calcium carbonate|DIETARY_SUPPLEMENT: Daily1500 mg elemental calcium as calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comprehensive Intensive Stroke Rehabilitation
Status: RECRUITING
Conditions: Stroke|Rehabilitation|Physical Therapy Modalities
Interventions: BEHAVIORAL: Neuroproprioceptive "facilitation, inhibition"|BEHAVIORAL: Technology based physical therapy|BEHAVIORAL: Effectively managed rehabilitation implementing the recommendations of the World Health Organization|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effects of Oxycodone and Sufentanil on Cardiovascular Stress Induced by Tracheal Intubation in the Patients With Coronary Heart Disease Undergoing Major Noncardiac Surgery
Status: COMPLETED
Conditions: Cardiovascular
Interventions: DRUG: Oxycodone 10mg|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Use of a Novel Drug in People With Non-alcoholic Steatohepatitis (NASH) or Non-alcoholic Fatty Liver Disease (NAFLD)
Status: TERMINATED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: AZ compound|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma
Status: SUSPENDED
Conditions: Advanced Melanoma
Interventions: DRUG: Botensilimab|DRUG: Balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Treatment Adherence in Patients Treated With Oral Targeted Therapy in Oncology Supported by a Dedicated and Coordinated Follow-up Compared to Standard Follow-up.
Status: COMPLETED
Conditions: Metastatic Solid Tumor
Interventions: OTHER: Dedicated and coordinated follow-up|OTHER: Standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Progranulin and FAM19A5 Protein Blood Levels in Metabolic Syndrome
Status: UNKNOWN
Conditions: Nutrition Disorders|Hypertension|Dyslipidemias|Glucose Intolerance|Glucose Metabolism Disorders|Obesity|Overweight and Obesity|Metabolic Syndrome
Interventions: DIAGNOSTIC_TEST: Blood sample collection|DIAGNOSTIC_TEST: Hair sample collection|DIAGNOSTIC_TEST: Urine sample collection|DIAGNOSTIC_TEST: Body composition analysis|DIAGNOSTIC_TEST: Questionnaires|DIAGNOSTIC_TEST: Blood pressure, pulse and blood oxygen saturation measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Results of the Treatment of Medium and Long de Novo and Restenotic Lesions in the Superficial Femoral Artery and/or Popliteal Artery With Primary or Salvage Pulsar® -18 t3 Stent
Status: NOT_YET_RECRUITING
Conditions: Peripheral Artery Disease (PAD)
Interventions: DEVICE: Stent PULSAR® -18 T3,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intermittent vs. Continuous Dorsal Root Ganglion Stimulation
Status: UNKNOWN
Conditions: Pain, Intractable|Pain, Chronic
Interventions: DEVICE: Dorsal Root Ganglion Stimulation (DRG-S)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Peer Referral Incentives to Increase Demand for Voluntary Medical Male Circumcision in Zambia
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: Peer-referral incentive program to increase VMMC uptake
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Apneas|Bradycardia
Interventions: DEVICE: Pacifier
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: DRUG: Placebo|DRUG: Fulranumab 1 mg|DRUG: Fulranumab 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GP2013 in Japanese Patients With CD20 Positive Low Tumor Burden Indolent B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Indolent B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: GP2013
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty
Status: COMPLETED
Conditions: Dermatochalasis of Eyelid|Ocular Surface Disease|Meibomian Gland Dysfunction|Dry Eye|Brow Ptosis
Interventions: PROCEDURE: Upper Eyelid Blepharoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Narcotics vs NSAIDs for Post-operative Analgesia in Outpatient Rhinoplasty
Status: COMPLETED
Conditions: Rhinoplasty|Non-steroidal Ant Inflammatory Drugs|Opioid Use
Interventions: DRUG: Norco|DRUG: NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) as a Cognitive Functioning Enhancement Treatment for ADHD Patients Compared to Healthy Controls
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Goal Oriented Activity for Latinos With Spine Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain|Neck Pain|Chronic Pain|Chronic Low-back Pain
Interventions: BEHAVIORAL: GOALS Intervention|BEHAVIORAL: Usual Care Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MDMA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device
Status: COMPLETED
Conditions: Autoimmune Diseases|Renal Disorders|Hematologic Disorders|Oncologic Disorders
Interventions: DEVICE: Therapeutic plasma exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of CDB-2914 in Comparison to Levonorgestrel for Emergency Contraception
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: CDB-2914|DRUG: Levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Berlin PRehospital Or Usual Delivery of Acute Stroke Care 2.0 (B_PROUD 2.0)
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: STEMO|PROCEDURE: Regular care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study)
Status: COMPLETED
Conditions: Uveitis
Interventions: DRUG: Ustekinumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ABT-700 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABT-700|DRUG: docetaxel|DRUG: FOLFIRI|DRUG: cetuximab|DRUG: erlotinib|DRUG: ABT-700
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b, Open-label, Dose-finding Study of AMG 706 in Combination With Gemcitabine and Erlotinib to Treat Subjects With Solid Tumors
Status: COMPLETED
Conditions: Histologically or Cytologically Documented Solid Tumors
Interventions: DRUG: AMG 706
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Adult Langerhans Cell Histiocytosis|Childhood Langerhans Cell Histiocytosis|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: PROCEDURE: Peripheral Blood Stem Cell Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of CYPHER® Sirolimus Stent and ENDEAVOR® Zotarolimus Stent in Patients With Acute ST Elevation Myocardial Infarction (STEMI) and Analysis of Current Status of Emergency PCI Green Channel for STEMI Patients in China
Status: UNKNOWN
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: DEVICE: Drug eluting coronary stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Anemia of Chronic Disease
Interventions: DRUG: Oral Calcitriol 0.5 mcg once daily for 6 weeks|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy of Anastrozole and Fulvestrant in Patients With ER Positive, HER2 Negative, Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabotypes in the Urinary Excretion of Flavan-3-ol Metabolites: "Metanols"
Status: SUSPENDED
Conditions: Diet Modification
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: green tea extract|DIETARY_SUPPLEMENT: grape seed|DIETARY_SUPPLEMENT: grape seed extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Characterize Epidemiology, Clinical and Genetic Features of Kallmann Syndrome in Finland
Status: ENROLLING_BY_INVITATION
Conditions: Kallmann Syndrome
Interventions: DRUG: Short withdrawal of testosterone, gonadotropins or estrogenic compounds (see below)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan
Status: TERMINATED
Conditions: Advanced Solid Tumors|Cancer|Advanced Solid Malignancies
Interventions: DRUG: AZD7762|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With and Without Ipilimumab and Radiation Therapy in Treating Patients With Recurrent or Resectable Undifferentiated Pleomorphic Sarcoma or Dedifferentiated Liposarcoma Before Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Dedifferentiated Liposarcoma|Recurrent Dedifferentiated Liposarcoma|Recurrent Undifferentiated Pleomorphic Sarcoma|Resectable Dedifferentiated Liposarcoma|Resectable Undifferentiated Pleomorphic Sarcoma|Undifferentiated Pleomorphic Sarcoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IDegLira
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: IDegLira|DRUG: insulin degludec|DRUG: Metformin|BEHAVIORAL: Lifestyle Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate
Status: COMPLETED
Conditions: Pleural Mesothelioma|Malignant Pleural Mesothelioma
Interventions: DRUG: Cisplatin|DRUG: Sodium Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter-directed Thrombolysis Compared to Anticoagulation Alone for Acute Primary Iliofemoral Deep Venous Thrombosis
Status: WITHDRAWN
Conditions: Deep Venous Thrombosis|Post Thrombotic Syndrome
Interventions: COMBINATION_PRODUCT: Catheter directed thrombolysis plus anticoagulation|DRUG: Anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individual and Contextual Factors That Influence Sexual Decisions
Status: UNKNOWN
Conditions: Binge Drinking|Unsafe Sex|HIV/AIDS|Sexually Transmitted Diseases
Interventions: OTHER: Alcohol Administration|OTHER: Placebo Alcohol Administration|OTHER: No Alcohol Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery
Status: NOT_YET_RECRUITING
Conditions: Sinusitis Chronic
Interventions: DRUG: GLS-1200|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery
Status: RECRUITING
Conditions: Weight Loss
Interventions: DIETARY_SUPPLEMENT: Essential Amino Acid Protein Supplement|DIETARY_SUPPLEMENT: Beneprotein®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Bevacizumab With Combined Radiotherapy for Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: AtezoBev with combined radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of The Effects of Dietary Oils on Fasting Lipoprotein Lipids
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: OTHER: Corn oil|OTHER: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intrinsic PEEP During Mechanical Ventilation of Patients With Obesity
Status: COMPLETED
Conditions: General Anesthesia|Laparoscopic Cholecystectomy
Interventions: DEVICE: RR 6 + 0|DEVICE: RR 10 + 0|DEVICE: RR 16 + 0|DEVICE: RR 6 + 5|DEVICE: RR 10 + 5|DEVICE: RR 16 + 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose:
Clinical trial: A Safety Study of Sativex Compared With Placebo (Both With Dose-intense Temozolomide) in Recurrent Glioblastoma Patients
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl
Status: UNKNOWN
Conditions: Normal Tension Glaucoma|Primary Open-angle Glaucoma|Glaucoma, Suspect|Ocular Hypertension
Interventions: DRUG: Eybelis ophthalmic solution 0.002%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-Randomized Evaluation of Carbon Dioxide Gas as a Contrast Agent in Comparison With Iodinated Contrast in Endovascular Aneurysm Repair
Status: COMPLETED
Conditions: Carbon Dioxide|Endovascular Abdominal Aortic Aneurym Repair|Prospective|Angiogram
Interventions: PROCEDURE: Carbon dioxide angiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Achieving Nutritional Adequacy Of Vitamins E and K With An Egg/Plant-Based Food Pairing - Study 1
Status: RECRUITING
Conditions: Nutritional Requirements
Interventions: OTHER: Zero hard-boiled egg at 0 h|OTHER: One hard-boiled egg at 0 h|OTHER: Two hard-boiled eggs at 0 h|OTHER: Three hard-boiled eggs at 0 h|OTHER: One hard-boiled egg at 3 h|OTHER: One hard-boiled egg at 0 h + One hard-boiled egg at 3 h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of EstroSense®/MD vs Placebo in Improving the Estrogen Profile in Females
Status: COMPLETED
Conditions: Estrogen Profile
Interventions: OTHER: EstroSense®/MD|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Men to Test How BI 1358894 is Taken up and Handled by the Body
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-radiolabelled BI 1358894|DRUG: BI 1358894
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Sustained Unresponsiveness to Sesame Using High- and Low-dose Sesame Oral Immunotherapy
Status: ENROLLING_BY_INVITATION
Conditions: Food Allergy
Interventions: DIETARY_SUPPLEMENT: High dose OIT|DIETARY_SUPPLEMENT: Low dose OIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib in Newly Diagnosed High Grade Glioma
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma|Anaplastic Astrocytoma|Anaplastic Oligoastrocytoma|Anaplastic Oligodendroglioma
Interventions: DRUG: Sorafenib dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT