pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolomics and Wound Healing in Diabetes
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Infection
Interventions: DIETARY_SUPPLEMENT: L-arginine supplements and nutritional supports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination of gp96-Ig Vaccine, Theophylline and Oxygen for the Treatment of Patients With Advanced, Relapsed or Metastatic Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer|Non-small-cell Lung Carcinoma|Lung Cancer|NSCLC
Interventions: BIOLOGICAL: gp96-Ig Vaccine|DRUG: Theophylline|OTHER: Oxygen|PROCEDURE: Immunologic Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of HMB Supplementation on Recovery Following ACL Surgery
Status: COMPLETED
Conditions: ACL Injury
Interventions: DIETARY_SUPPLEMENT: HMB|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Pediatric Obesity (TOP) - A Multidisciplinary Approach Involving Adolescents and Their Peers
Status: COMPLETED
Conditions: Obesity|Physical Activity|Sedentary Lifestyle
Interventions: BEHAVIORAL: Peer support|BEHAVIORAL: Regular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of Proton and Carbon Ion Irradiation for HER2 Positive and Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|HER2-positive Breast Cancer
Interventions: RADIATION: proton plus carbon ion radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease
Status: UNKNOWN
Conditions: Dry Eye Disease|Dry Eye Syndromes|Dry Eye
Interventions: DRUG: Methylhydroxypropylcellulose|DRUG: Carbomer|DRUG: TCM Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Ambulation After Adductor Canal Block for Total Knee Arthroplasty
Status: TERMINATED
Conditions: Pain|Osteoarthritis
Interventions: PROCEDURE: Canal Block and Capsular Injection|PROCEDURE: Femoral Nerve Block with Tibial Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Mode Selection Trial in Sinus Node Dysfunction (MOST)
Status: COMPLETED
Conditions: Arrhythmia|Cardiovascular Diseases|Heart Diseases|Sick Sinus Syndrome|Vascular Diseases|Cerebrovascular Accident
Interventions: DEVICE: pacemaker, artificial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation
Status: UNKNOWN
Conditions: Hearing Loss
Interventions: DRUG: Proton pump inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Carcinoma|Intrahepatic Cholangiocarcinoma|Digestive System Neoplasms|PD-1 Inhibitor|First-line Treatment
Interventions: DRUG: Pemigatinib|DRUG: PD-1 Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Cisplatin for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Azacitidine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Patient Reported Health Status Questions Via Four Different Methods of Administration, in Stroke Survivors.
Status: COMPLETED
Conditions: Stroke|Cerebral Infarction|Cerebral Hemorrhage|Stroke Hemorrhagic|Stroke, Ischemic|Stroke of Uncertain Pathology
Interventions: OTHER: 15 Patient Reported Health Status Questions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Status: RECRUITING
Conditions: Spatial Navigation
Interventions: DEVICE: Active 10-Hz TMS to the parietal cortex|DEVICE: Active single pulse TMS to the parietal cortex|DEVICE: Sham 10-Hz TMS to the right parietal cortex|DEVICE: Sham single-pulse rTMS the rigt parietal cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exercise Intermittent Isometric Handgrip and Blood Flow Restriction
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Isometric exercise Intermittent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ToothWave Calculus Reduction and Accumulation Prevention Study
Status: COMPLETED
Conditions: Gingivitis|Plaque|Calculus, Dental
Interventions: DEVICE: RF-utilizing powered toothbrush|DEVICE: Control placebo with no RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Recurrent Breast Cancer|Advanced Malignancies
Interventions: DRUG: TQB2930 for injection|DRUG: Paclitaxel for injection (albumin-bound)|DRUG: TQB3616 capsule|DRUG: Fulvestrant injection|DRUG: Capecitabine tablets|DRUG: Vinorelbine tartrate injection|DRUG: Eribulin mesylate injection|DRUG: gemcitabine hydrochloride for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of the Sound Generator Combined With Conventional Amplification for Tinnitus Control: Blind Randomized Clinical Trial
Status: COMPLETED
Conditions: Tinnitus|Hearing Loss
Interventions: DEVICE: sound generator|DEVICE: hearing aids with only amplification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AB-Intra- and Post-Operative Measures of Auditory Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss|Cochlear Implant
Interventions: OTHER: Electrocochleography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mifepristone-misoprostol vs. Misoprostol Alone for Second Trimester Fetal Death
Status: TERMINATED
Conditions: Fetal Death
Interventions: DRUG: Mifepristone|DRUG: Placebo|DRUG: Misoprostol 200mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ST266 Eye Drops in Treating Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: ST266|DRUG: Refresh Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Barium Swallow in Measuring Swallowing Function After Surgery in Patients With Oropharyngeal Cancer
Status: WITHDRAWN
Conditions: Oropharyngeal Cancer
Interventions: PROCEDURE: diagnostic imaging|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major
Status: COMPLETED
Conditions: Iron Overload|Cardiomyopathy
Interventions: DRUG: Deferoxamine and Deferiprone|DRUG: Deferoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microcurrent and Aerobic Exercise Effects on Abdominal Fat
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: DEVICE: Exercise after|DEVICE: Exercise at same time|DEVICE: Transcutaneos|DEVICE: percutaneous microcurrent|DEVICE: 25-10Hz|DEVICE: 25-50Hz microcurrent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety of SPD422 in Japanese Adults With Essential Thrombocythaemia
Status: COMPLETED
Conditions: Essential Thrombocythemia (ET)
Interventions: DRUG: SPD422 (anagrelide hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer
Status: WITHDRAWN
Conditions: Breast Carcinoma|Colon Carcinoma|Kidney Carcinoma|Lymphoma|Non-Small Cell Lung Carcinoma|Prostate Carcinoma
Interventions: OTHER: Internet-Based Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Olive Leaf Extract on Blood Pressure in Overweight Prehypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Olive leaf extract liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SECURE®-C Cervical Artificial Disc Clinical Study/ SECURE-C Cervical Artificial Disc Postmarket Approval Study
Status: COMPLETED
Conditions: Symptomatic Cervical Disc Disease
Interventions: DEVICE: SECURE-C Cervical Artificial Disc|DEVICE: ASSURE Cervical plate and an allograft interbody spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 24 Hour Ambulatory Cardiac Oxygen Consumption
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan|DRUG: Nebivolol|DRUG: Nebivolol/valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery
Status: NOT_YET_RECRUITING
Conditions: Suture, Complication|Hand Infection|Skin Infection|Scar|Symptoms and Signs
Interventions: DEVICE: Skin closure at end of hand surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Pasireotide Long Acting Release (LAR) in Patients With Metastatic Neuroendocrine Tumors (NETs)
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Carcinoid Tumors
Interventions: DRUG: Pasireotide Long Acting Release (LAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Scores as Indication of Response to Subcutaneous Abatacept in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy Study in the Treatment of Pediatric Crohn's Disease
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: Sargramostim (Leukine)|DRUG: Sargramostim (Leukine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Carboplatin and Bevacizumab (Avastin) for ER Neg, PR Neg, and HER2/Neu Neg Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: carboplatin|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib and Etoposide in Treating Patients With Advanced Prostate Cancer That Did Not Respond to Hormone Therapy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Gefitinib plus etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Niraparib and Dostarlimab Therapy for Recurrent or Persistent Uterine Serous Carcinoma
Status: RECRUITING
Conditions: Recurrent Endometrial Serous Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Dostarlimab|PROCEDURE: Magnetic Resonance Imaging|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Dalcetrapib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Esketamine on Acute Abdominal Pain After TACE in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Transcatheter Arterial Chemoembolization|Pain
Interventions: DRUG: Esketamine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of an ASC-seeded Collagen Hydrogel on Cerebrospinal Fluid Leak Rates Following Skull Base Surgery
Status: WITHDRAWN
Conditions: CSF Leak
Interventions: DEVICE: Duragen with Collagen Hydrodel and ASCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Ilaprazole to Treat Erosive Esophgitis
Status: COMPLETED
Conditions: Erosive Esophagitis|GERD
Interventions: DRUG: Ilaprazole|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture for the Treatment of Parkinson's Disease Related Constipation
Status: RECRUITING
Conditions: Parkinson Disease|Constipation|Non-motor Symptom|Randomized Controlled Trial
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children
Status: TERMINATED
Conditions: Renal Insufficiency|Infection
Interventions: DRUG: Low-dose intravenous cyclophosphamide|DRUG: High-dose intravenous cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development
Status: UNKNOWN
Conditions: IVF Failure
Interventions: DRUG: Sildenafil Citrate|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Status: NOT_YET_RECRUITING
Conditions: Analgesia, Obstetrical|Post-Dural Puncture Headache
Interventions: PROCEDURE: Resiting Epidural Catheter|PROCEDURE: Intrathecal Catheter Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Trial to Evaluate the Efficacy and Safety of SCTV01E in Healthy People
Status: NOT_YET_RECRUITING
Conditions: COVID-19 SARS-CoV-2 Infection
Interventions: BIOLOGICAL: CoronaVac|BIOLOGICAL: SCTV01E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis|Respiratory Function|Scopolamine
Interventions: DRUG: Scopolamine, atropine, edaravone and dexmedetomidine|DRUG: Edaravone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Zaldiar With Intravenous Paracetamol and Tramadol
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Zaldiar|DRUG: Paracetamol-Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy (RECOVER)
Status: UNKNOWN
Conditions: Large Vessel Occlusion|Acute Ischemic Stroke|Cerebrovascular Disorders
Interventions: DEVICE: Aspiration Catheter|DEVICE: Solitaire FR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy an Safety of Volinanserin on Sleep Maintenance Insomnia With a Sub-study on Stable Type II Diabetes Mellitus
Status: TERMINATED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Volinanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart Failure
Status: WITHDRAWN
Conditions: Congestive Heart Failure
Interventions: DRUG: Pantoprazole|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Therapy and Transcutaneous Electrical Nerve Stimulation on Chronic Neck Pain Patients
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: DEVICE: Active PBM|DEVICE: Active TENS|DEVICE: Placebo PBM|DEVICE: Placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Lightweight Mesh in the Laparoscopic Prevention of Parastomal Hernia
Status: COMPLETED
Conditions: Parastomal Hernia
Interventions: DEVICE: Lightweight polipropilene and poliglecaprone 25 and oxidized cellulose mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Theta Burst Transcranial Magnetic Stimulation of Fronto-parietal Networks: Modulation by Mental State
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: TMS|BEHAVIORAL: n-back working memory task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open Uncontrolled Validation Study for the German Version of the Actinic Keratosis Quality of Life Questionnaire (AKQoL)
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: OTHER: cognitive interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Trial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: midostaurin (PKC412)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phospholipase A2 Receptor (PLA2R1) Autoantibodies in Membranous Nephropathy in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: OTHER: Anticorps anti-PLA2R1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Platelet-Rich Plasma and Additional Exercise and Exercise Only in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Group A|OTHER: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
Status: COMPLETED
Conditions: Colorectal Cancer Screening
Interventions: DEVICE: COLON Capsule endoscopy|DEVICE: Computed Tomographic Colonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Embryo Transfer Procedure Guided by Transvaginal Ultrasound Versus Abdominal Ultrasound in Oocytes Recipients
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: ultrasound-guided embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2i on the Cognitive Function in T2DM Patient (ESCDP)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cognitive Functions Confusion
Interventions: DRUG: Canagliflozin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics on Intestinal Inflammation in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patients Undergoing Continuous Venovenous Hemodiafiltration: Effects of Increased Blood Flow
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Effects of increased blood flow during regional anticoagulation with 4% trisodium citrate in patients undergoing continuous venovenous hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagenase Clostridium Histolyticum for Refractory Iatrogenic Esophageal Strictures
Status: TERMINATED
Conditions: Stricture|Esophageal Stricture|Anastomotic|Collagenosis
Interventions: DRUG: Collagenase histiolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess PV-10 Chemoablation of Cancer of the Liver
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Metastatic to the Liver|Hepatocellular Carcinoma|Metastatic Melanoma|Metastatic Ocular Melanoma|Metastatic Uveal Melanoma|Metastatic Lung Cancer|Metastatic Colon Cancer|Metastatic Colorectal Cancer|Metastatic Breast Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: PV-10 (10% rose bengal disodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas
Status: COMPLETED
Conditions: Zika Virus
Interventions: BIOLOGICAL: mRNA-1893|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: O2Optix contact lens|DEVICE: Proclear contact lens|DEVICE: ReNu MultiPlus Multi-Purpose Solution|DEVICE: Clear Care Cleaning and Disinfecting Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the ALLEGRA THV System With a New Delivery System in Patients With Aortic Stenosis or Failed Surgical Bioprosthesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Transcatheter Aortic Valve Implantation
Interventions: DEVICE: (ALLEGRA Transcatheter Heart Valve) TAVI in severe calcified aortic stenosis or in failed surgical aortic bioprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoid Syndrome|Carcinoid Tumor|Digestive System Neuroendocrine Tumor G1|Metastatic Carcinoid Tumor
Interventions: PROCEDURE: Dual-Energy Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Single administration Amg dose Group|DRUG: Single administration Bmg dose Group|DRUG: Single administration Cmg dose Group|DRUG: Single administration Dmg dose Group|DRUG: Single administration Emg dose Group|DRUG: Single administration Amg dose Group-Placebo|DRUG: Single administration Bmg dose Group-Placebo|DRUG: Single administration Cmg dose Group-Placebo|DRUG: Single administration Dmg dose Group-Placebo|DRUG: Single administration Emg dose Group-Placebo|DRUG: Multiple administration Amg dose group|DRUG: Multiple administration Bmg dose group|DRUG: Multiple administration Cmg dose group|DRUG: Multiple administration Dmg dose group|DRUG: Multiple administration Emg dose group|DRUG: Multiple administration Amg dose group - Placebo|DRUG: Multiple administration Bmg dose group - Placebo|DRUG: Multiple administration Cmg dose group - Placebo|DRUG: Multiple administration Dmg dose group - Placebo|DRUG: Multiple administration Emg dose group - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of a Chikungunya Vaccine, PXVX0317 CHIKV-VLP, in Healthy Adults
Status: COMPLETED
Conditions: Chikungunya Virus Infection
Interventions: BIOLOGICAL: CHIKV VLP/unadjuvanted|BIOLOGICAL: CHIKV VLP/adjuvanted|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: tasimelteon|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Fluoroscopy and Ultrasonography Guidance in Sacroiliac Joint Injections
Status: RECRUITING
Conditions: Sacroiliac Joint Somatic Dysfunction|Sacroiliac Joint Pain
Interventions: OTHER: Combined ultrasonography and flouroscopy guided injeciton|OTHER: Flouroscopy guided injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is an Open-label, Multi-center, Extension Study Designed to Evaluate the Longer Term Safety, Tolerability and Effectiveness of Lurasidone, Flexibly Dosed, Adjunctive to Lithium or Divalproex for the Treatment of Subjects With Bipolar I Disorder Who Have Participated in Study D1050296
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Lurasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study on Safety and Immunogenicity of Influenza A (H7N9) Vaccine in the Population
Status: COMPLETED
Conditions: Influenza A
Interventions: BIOLOGICAL: Influenza A (H7N9) virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neuropathic Pain and Postural Stability in Patients With Lumbar Radiculopathy
Status: ENROLLING_BY_INVITATION
Conditions: Postural Stability|Balance; Distorted|Neuropathic Pain
Interventions: DEVICE: Biodex Balance System™ SD|OTHER: questionnaires and inventories
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD")
Status: TERMINATED
Conditions: Lung Diseases, Obstructive|Sarcoidosis|Wegener's Granulomatosis|Rhinoscleroma|Recurrent Respiratory Papillomatosis
Interventions: DEVICE: CryoSpray Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for the Treatment of Acute Asthma in Wheezy Pre-school Aged Children
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Azithromycin|DRUG: Suspension Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Radiolabeled Monoclonal Antibody Anti-B1 for the Treatment of B-Cell Lymphomas and Extended Study to Determine the Safety and Efficacy of Coulter Clone® 131Iodine-B1 Radioimmunotherapy of Advanced Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Radiolabeled Monoclonal Antibody Anti-B1 for the Treatment of B-Cell Lymphomas (Tositumomab and Iodine I 131 Tositumomab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Remimazolam Tosilate in Patients Undergoing Colonoscopy
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Remimazolam Tosilate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Intra articular injection Group|DEVICE: Radiofrequency Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pylorus Dysfunction After Esophagectomy and Gastric Tube Reconstruction. Effect of Pneumatic Pylorus Dilatation During Hospital Stay, Surgical Complications During in Hospital Stay
Status: UNKNOWN
Conditions: Esophagectomy|No Signs of Cancer Recurrence|Delayed Gastric Emptying
Interventions: DEVICE: Pneumatic pyloric dilatation|OTHER: 15 mm pyloric balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Glycemic Index Diets (With Pulses) in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Low glycemic index diet with pulses|DIETARY_SUPPLEMENT: High Cereal Fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of 177Lu-DOTATATE Radionuclide in Adults With Progressive or High-risk Meningioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Meningioma
Interventions: DRUG: Lutathera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization
Status: COMPLETED
Conditions: Cardiac Conduction and Repolarization
Interventions: DRUG: Custirsen|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-time-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of GSK189075A in Healthy Subjects and in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK189075A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-add Multifocal vs. Monofocal IOLs
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: Low-add multifocal IOL|DEVICE: Monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Narcotrend Index and the Observer's Assessment of Alertness/Sedation (OAA/S) Scale
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-week Open Label Cross-over Study With 2 Different Daily Doses of Minirin® Oral Lyophilisate in Children and Adolescents With Primary Nocturnal Enuresis (PNE)
Status: COMPLETED
Conditions: Primary Nocturnal Enuresis
Interventions: DRUG: MINIRIN Oral Lyophilisate|DRUG: Minirin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neo-Adjuvant Bladder Urothelial Carcinoma COmbination-immunotherapy
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-ERCP Pancreatitis by Indomethacin vs Diclofenac
Status: RECRUITING
Conditions: Post-ERCP Acute Pancreatitis|NSAIDs|Indomethacin|Diclofenac|Endoscopic Retrograde Cholangiopancreatography
Interventions: DRUG: 100mg diclofenac|DRUG: 100mg indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Aneurysmal Subarachnoid Hemorrhage|Cerebral Vasospasm
Interventions: DRUG: Simvastatin 40 mg|DRUG: Placebo|DRUG: Simvastatin 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total Gastrectomy
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopy-assisted gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing
Status: TERMINATED
Conditions: Hip Arthroplasty
Interventions: DRUG: Extended Release Epidural Morphine (EREM)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis
Status: UNKNOWN
Conditions: Intrabony Defects in Chronic Periodontitis
Interventions: DRUG: Placebo gel|DRUG: 1 % Metformin gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sheathotomy vs. Intravitreal Triamcinolone for Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Macular Edema|Branch Retinal Vein Occlusion
Interventions: PROCEDURE: Arteriovenous Crossing Sheathotomy|PROCEDURE: Intravitreal Triamcinolone Acetonide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Intravascular Cooling in the Treatment of Stroke 2/3 Trial
Status: TERMINATED
Conditions: Stroke, Acute
Interventions: DEVICE: hypothermia and anti-shivering treatment|DRUG: Group1: IV t-PA and normothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of an Herbal Tea on Immune Surveillance and Activation.
Status: COMPLETED
Conditions: Active Immune Response
Interventions: DIETARY_SUPPLEMENT: Herbal tea blend|DIETARY_SUPPLEMENT: Warm water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Once-daily Therapy for Streptococcal Pharyngitis
Status: COMPLETED
Conditions: Streptococcal Sore Throat
Interventions: DRUG: Amoxicillin|DRUG: Intramuscular Benzathin Penicillin G
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Eribulin for the Treatment of Advanced Breast Cancer Refractory to All Other Marketed Therapies
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Radiation Toxicity
Interventions: DIETARY_SUPPLEMENT: EGb761|DRUG: donepezil hydrochloride|PROCEDURE: cognitive assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of STX-100 in Renal Transplant Patients With Interstitial Fibrosis and Tubular Atrophy (IF/TA)
Status: WITHDRAWN
Conditions: Chronic Allograft Dysfunction
Interventions: BIOLOGICAL: STX-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
Status: COMPLETED
Conditions: Total Knee Replacement Surgery
Interventions: DEVICE: Ioban 2 incision drape, 3M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Untersuchung Zur Erfassung Und Kontrolle Der Lebensqualität Unter Einer Therapie Mit Pollinex Quattro Bei Heuschnupfen
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: OTHER: Quality of life under or after therapy with Pollinex quattro
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Safety and Efficacy of Pancrecarb® MS-16 in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Insufficiency
Interventions: DRUG: PANCRECARB® (pancrelipase)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)
Status: COMPLETED
Conditions: Schizophrenia|Schizophrenia; Psychosis
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Switch Maintenance vs Delayed Second-line Nivolumab in Advanced Stage Squamous Non-small Cell Lung Cancer (NSCLC) Patients (EDEN Trial)
Status: UNKNOWN
Conditions: Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Nivolumab 10 MG/ML Intravenous Solution|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.
Status: COMPLETED
Conditions: Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology
Interventions: PROCEDURE: one single blastocyst transfer, both fresh and warmed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Artery Disease
Interventions: DRUG: Pitavastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of an Acupuncture Session in Healthy Volunteers on the Kinetics of Cerebral Activity Using the Bispectral Index (BIS)
Status: COMPLETED
Conditions: Acupuncture|Healthy Volunteers
Interventions: PROCEDURE: Acupuncture|BEHAVIORAL: A digital stress scale|BEHAVIORAL: a relaxation questionnaire|DIAGNOSTIC_TEST: Bispectral Index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Acupuncture for Overactive Bladder in Adults
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: OTHER: Acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Arm Casting Effective in Type A2 Fractures in the Distal Radius
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Casting (long arm)|PROCEDURE: Casting (short arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: feediNg gUidelines infanT RandomIzEd coNtrolled Trial
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: BEHAVIORAL: Provision of extended information on the conduct of complementary feeding|BEHAVIORAL: Provision of current official information on complementary feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Eye-ECG Approach to Emergencies : Diagnostic Performance of the HINTS Test
Status: COMPLETED
Conditions: Acute Vestibular Syndrome|Emergencies
Interventions: DIAGNOSTIC_TEST: HINTS Test|DIAGNOSTIC_TEST: STANDING Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in Inflammatory Biomarkers Including Soluble CD14 and Hyperreflective Foci in DME Patients Treated With Aflibercept (FORESIGHT)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaginal Hygiene Wash as Adjunct Treatment in Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginoses
Interventions: OTHER: Vaginal hygiene wash|OTHER: placebo wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT