pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Belatacept 3 Month Post Transplant Conversion Study
Status: COMPLETED
Conditions: Transplant; Failure, Kidney|EBV
Interventions: DRUG: belatacept|DRUG: Tacrolimus|DRUG: MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Integrative and Intensive Virtual Rehabilitation Program for Service Members Post TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: BrightBrainer Virtual Reality (BBVR) Rehabilitation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Public Health Model of Latent Tuberculosis Infection Control for High-Risk Adolescents
Status: COMPLETED
Conditions: Lung Diseases|Tuberculosis
Interventions: BEHAVIORAL: Adherence Program|BEHAVIORAL: Life Skills and Self-Esteem Training Program (Attention Control Arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Sodium Diet in Oligohydramnios Assigned for Conservative Management
Status: UNKNOWN
Conditions: Oligohydramnios
Interventions: OTHER: low sodium diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Integrated Nursing Strategy for Patients With Gastrointestinal Stromal Tumors After Targeted Therapy
Status: RECRUITING
Conditions: Nursing Caries|Gastrointestinal Stromal Tumors
Interventions: DEVICE: integrated care mode|DEVICE: conventional care mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Secondhand Tobacco Smoke and Cardiovascular Disease
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Scapular Proprioceptive Neuromuscular Facilitation Techniques on Pain and Functionality in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Scapular PNF|OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care
Status: COMPLETED
Conditions: PTSD|Depression|Substance Use Disorder|Traumatic Brain Injury
Interventions: BEHAVIORAL: WEB-ED+ Treatment Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine, Busulfan, and Total Body Irradiation (TBI)
Status: UNKNOWN
Conditions: AML|MDS|ALL|CML|Lymphoma
Interventions: DRUG: fludarabine phosphate, busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Efficacy of Autogenous Tumor Infiltrates Lymphocytes for the Treatment of Advanced Solid Tumor
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: HS-IT101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI
Status: TERMINATED
Conditions: Dyslipidemia|Glucose Metabolism Disorder
Interventions: DRUG: fenofibrate (F) + metformin (M) hydrochloride fixed combination|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Displacement Between PVC and Silicon DLT
Status: COMPLETED
Conditions: Endotracheal Tube Wrongly Placed During Anesthetic Procedure|Surgical Procedure, Unspecified
Interventions: DEVICE: PVC DLT|DEVICE: silicon DLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: MOCA Versus RFA in the Treatment of Primary Great Saphenous Varicose Veins
Status: COMPLETED
Conditions: Greater Saphenous Vein Injury
Interventions: DEVICE: Mechanochemical Endovenous Ablation (MOCA)|PROCEDURE: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of ELAPR in Women With Striae Distensae Alba
Status: COMPLETED
Conditions: Striae Distensae
Interventions: DEVICE: ELAPR002f|DEVICE: ELAPR002g|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Chinese Medicine on Metabolomics in Menopausal or Postpartum Women
Status: UNKNOWN
Conditions: Menopausal Women
Interventions: DRUG: Finished Herbal Product such as Suan Tsao Jen Tang, Jia-Wey Shiau-Yau San
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study on People Who Inject Drugs in Senegal
Status: UNKNOWN
Conditions: Drug Addiction|HIV/AIDS|Hepatitis C, Chronic|Hepatitis C, Acute|Hepatitis B, Chronic|Hepatitis B Acute|Tuberculosis|Sexually Transmitted Diseases|Psychiatric Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Novel Endpoints in Cough Challenge Testing
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Healthy|Chronic Cough|Smokers
Interventions: OTHER: Cough challenge test|OTHER: 24 hour ambulatory cough recording|OTHER: Cough quality of life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Alternating Current Stimulation Treating Post-stroke Depression
Status: UNKNOWN
Conditions: Post-stroke Depression
Interventions: DEVICE: NEXALIN ADI AC stimulator|DEVICE: Pseudo-stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Icotinib|RADIATION: SRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin Sensitivity
Status: SUSPENDED
Conditions: Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Carbohydrate Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CS-7017 in Combination With Erlotinib in Subjects With Stage IIIb/IV Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CS-7017|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type I Diabetes
Interventions: DRUG: Ladarixin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Hemofiltration During Cardiopulmonary Bypass and Its Effect on Lactatemia
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: PROCEDURE: Polysulfone Filter|PROCEDURE: Procedure/ Surgery: without Polysulfone Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics, Safety and Efficacy of Advagraf and Prograf in de Novo Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: DRUG: Advagraf|DRUG: Prograf|DRUG: Prograf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establishing Organoids From Metastatic Pancreatic Cancer Patients, the OPT-I Study.
Status: UNKNOWN
Conditions: Carcinoma, Pancreatic Ductal
Interventions: DIAGNOSTIC_TEST: biopsies & blood analyses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Prospective, Single Arm, Open Label, Proof of Concept Clinical Study of Sulfasalazine in the Treatment of Active Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Sulfasalazine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Leukemia|Lymphoma|Childhood Cancer
Interventions: DEVICE: Headspace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease
Status: UNKNOWN
Conditions: Autoimmune|Behcet Syndrome
Interventions: RADIATION: Diode laser 980nm&100 mWatt|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, and Pharmacokinetics (PK) of SR750 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SR750 tablet|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy in Women With Peripheral Persistent Pain Following Breast Cancer Treatment
Status: COMPLETED
Conditions: Shoulder Pain|Breast Cancer
Interventions: OTHER: Shoulder Conventional Exercises|OTHER: Multimodal Physiotherapy|OTHER: Scapular exercises|BEHAVIORAL: Therapeutic Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic HCT Using Uniform Conditioning Regimen Regardless of Donors (MS, MU, or HF) for AML in Remission
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: allogeneic hematopoietic cell transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Single ascending doses of IOA-289|DRUG: Placebo single doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Availability of Showerpatch for Patients With Intravenous Catheters
Status: TERMINATED
Conditions: Cystic Fibrosis|Pulmonary Hypertension|Neoplasms
Interventions: DEVICE: Shower patch IV catheter protection|DEVICE: Conventional IV catheter protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Effects of Different Noninvasive Ventilation Mode on Neural Respiratory Drive in Recovering AECOPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: noninvasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Duloxetine for Postoperative Analgesia After Modified Radical Mastectomy
Status: UNKNOWN
Conditions: Modified Radical Mastectomy|Postoperative Analgesia
Interventions: PROCEDURE: Acetaminophen group|PROCEDURE: Duloxetine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)
Status: COMPLETED
Conditions: Hyponatremia|Hyponatremic|Pituitary Tumor|Pituitary|Surgery
Interventions: OTHER: Fluid Restricted Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis on the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Placebo|BIOLOGICAL: Certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Online Memory & Aging Program and Online Goal Management Training
Status: COMPLETED
Conditions: Aging|Cognitive Decline
Interventions: BEHAVIORAL: Goal Management Training|BEHAVIORAL: Memory & Aging Program|BEHAVIORAL: Cambridge Brain Sciences
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Nutraceutical "Hemofix" on the Coagulation System
Status: WITHDRAWN
Conditions: Von Willebrand Disease|Menorrhagia
Interventions: DIETARY_SUPPLEMENT: HEMOFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Clinical Evaluation Between a Novel Self Adhesive and Conventional Bulk-fill Composites
Status: COMPLETED
Conditions: Class II Dental Caries
Interventions: OTHER: Surefil one®|OTHER: Filtek One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High Versus Low Target Mean Arterial Pressure in Septic Shock in Critically Ill Cirrhotics
Status: COMPLETED
Conditions: Cirrhosis
Interventions: OTHER: High Target Mean Arterial Pressure|OTHER: Low Target Mean Arterial Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Trigeminal Neuralgia and Peripheral Neuropathy
Status: RECRUITING
Conditions: Peripheral Neuropathy|Trigeminal Neuralgia
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexamethasone on Labor Induction
Status: COMPLETED
Conditions: Dexamethasone|Pregnancy
Interventions: DRUG: Dexamethasone 0.5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Comparison of Conservative and Opertaive Treatment of Radius Fractures in Elderly Patients
Status: RECRUITING
Conditions: Orthopedic Disorder
Interventions: DEVICE: Palmar Plate Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
Status: WITHDRAWN
Conditions: Hip Fracture
Interventions: PROCEDURE: Femoral Nerve Catheterization|PROCEDURE: Intravenous Opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Taxol|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self-rehabilitation Using Communication APP After Arthroscopic Surgery for Rotator Cuff Tear
Status: RECRUITING
Conditions: Rotator Cuff Tears
Interventions: BEHAVIORAL: Home-based rehabilitation supporting with the mobile application|BEHAVIORAL: Supervised rehabilitation by the therapist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prior CABG Patients Evaluated for Saphenous VeIn grAft DysfUnction and Progression of Coronary arTery Disease
Status: RECRUITING
Conditions: Recurrent Angina After Coronary Artery Bypass Graft|Graft Failure|Coronary Artery Disease Progression
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance of Baccalaureate Nursing Students in Insertion of Laryngeal Mask: a Trial in Mannequins
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: OTHER: Simulation class|OTHER: Exhibition-dialogued class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Rituximab, Cyclophosphamide, Bortezomib, and Prednisone in Patients With Stage III/IV FL or MZL
Status: TERMINATED
Conditions: Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Rituximab|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Enzalutamide in Combination With AZD5363 in Patients With mCRPC
Status: UNKNOWN
Conditions: Adenocarcinoma of the Prostate
Interventions: DRUG: AZD5363|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Cognitive Effects of 'Brainwaves' Supplementation in Cognitively Intact Older Adults
Status: COMPLETED
Conditions: Cognitive Change|Mood Change|Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Turmeric Brainwave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Ascending Dose Study to Assess Safety, Tolerability, PK/PD of LHW090 in Healthy Volunteers and in Subjects With Renal Dysfunction
Status: COMPLETED
Conditions: Chronic Renal Insufficiency
Interventions: DRUG: LHW090|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rosiglitazone XR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Coconut Oil Cream as a Prevention Treatment for Occupational Hand Dermatitis Among Batik Workers
Status: COMPLETED
Conditions: Hand Dermatoses
Interventions: DRUG: Cocos Nucifera Whole|DRUG: Cocos Nucifera Whole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Dexamethasone Phosphate Ophthalmic|DRUG: 100 mM Sodium Citrate Buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Digestive System Neuroendocrine Neoplasm|Metastatic Neuroendocrine Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Lutetium Lu 177 Dotatate|PROCEDURE: Magnetic Resonance Imaging|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise Training in Individuals Aged 60 and Older With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Progressive Resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion for Comorbid PTSD and Chronic Pain
Status: COMPLETED
Conditions: PTSD|Chronic Pain
Interventions: DRUG: A single low dose ketamine infusion as compared to the IV infusion of active placebo - ketorolac on chronic pain and PTSD symptoms.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Index Variations In the Early Period Following Bariatric Surgery
Status: WITHDRAWN
Conditions: Diabetes Mellitus|Bariatric Surgery Candidate
Interventions: DIAGNOSTIC_TEST: Continuous Glucose monitoring in the perioperative period
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Preoperative Prehabilitation With a Home-based Supervised Exercise Program Against an Unsupervised Exercise Program for Frail Elderly Patients Undergoing Major Abdominal Surgery
Status: UNKNOWN
Conditions: Frail Elderly Syndrome|Frailty|Surgery
Interventions: OTHER: Home-based supervised exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder.
Status: COMPLETED
Conditions: Social Anxiety Disorder (SAD)
Interventions: DEVICE: BVR-100|DEVICE: BES-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment II Study (SMAART II)
Status: NOT_YET_RECRUITING
Conditions: Stroke|Medication Adherence
Interventions: DRUG: Polycap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma
Status: COMPLETED
Conditions: Fatigue
Interventions: DRUG: armodafinil 150 mg|OTHER: Placebo|DRUG: armodafinil 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Magnetic Stimulation (rTMS) and Autism.
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (rTMS)|DEVICE: Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesiotaping and Stretching on SKM and Upper Trapezius Muscle in TMD Patients
Status: COMPLETED
Conditions: TMJ Disc Disorder|Myofascial Pain
Interventions: OTHER: Kinesiotaping Group|OTHER: Stretching Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy Adults
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: RXI-109|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir DF + Efavirenz (TDF+EFV) Versus Tenofovir DF + Efavirenz + Lamivudine (TDF+EFV+3TC) Maintenance Regimen in Virologically Controlled Patients: COOL Trial
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: EFV+TDF|DRUG: EFV+3TC+TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Mobilization With Movement Versus Mulligan Knee Taping Technique on Patellofemoral Pain Syndrome.
Status: COMPLETED
Conditions: Patellofemoral Syndrome
Interventions: OTHER: Moblization with Movement|OTHER: Mulligan knee taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring Resuscitation
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy|Perinatal Asphyxia
Interventions: PROCEDURE: Umbilical cord milking|PROCEDURE: Immediate cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Randomized, Single Period, Parallel-Cohort Study To Evaluate Serum and Pulmonary Pharmacokinetics Following Single and Multiple Dose Administration of Intravenous GSK2251052 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Community-acquired Infection
Interventions: DRUG: GSK2251052
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Neoplasm Malignant Stage I
Interventions: DRUG: Megestrol Acetate 160 MG Oral Tablet|DRUG: Medroxyprogesterone Acetate 500 MG|DRUG: Triprorelin Acetate|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Depression Via E-Health Access (IDEA) Study
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Moodkit|BEHAVIORAL: Moodgym|BEHAVIORAL: University of Michigan Depression Center Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ribociclib (LEE011) Rollover Study for Continued Access
Status: RECRUITING
Conditions: Continued Access to Study Treatment(s), Cancers With a Mass, Bulky Tumor, Nodule, Lump, Advanced Cancer, Advanced Solid Tumors, Advanced Solid Malignancies
Interventions: DRUG: LEE011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Three Controlled Ovarian Hyperstimulation Protocols in Poor Responding Infertility Patients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: FSH 225IU and hMG 225IU|DRUG: FSH 150IU and hMG 150IU|DRUG: Letrozole 5mg and hMG 150IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab Skin Toxicity Prevention Trial
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic|Skin Toxicity
Interventions: DRUG: Lycopene|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing Multiple Doses of VI-0521 With Placebo and Their Single-agent Constituents for Treatment of Obesity in Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: VI-0521|DRUG: VI-0521|DRUG: topiramate|DRUG: topiramate|DRUG: phentermine|DRUG: phentermine|DRUG: VI-0521
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preparing Heart and Mind™: A Patient Engagement Pathway for Parents and Their Caregiving Partners After a Major Fetal Anomaly Diagnosis
Status: COMPLETED
Conditions: Parent Mental Health
Interventions: BEHAVIORAL: PHM™ Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Estimation of Fetal Weight by MR Imaging to PREdict Neonatal MACROsomia (PREMACRO Study)
Status: COMPLETED
Conditions: Fetal Macrosomia
Interventions: OTHER: Ultrasound examination|OTHER: Magnetic resonance examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention and Reduction of Alcohol and Drug Problems in a Clinical Psychiatric Youth Population
Status: UNKNOWN
Conditions: Alcohol Abuse|Drug Abuse|Mood Disorder|Anxiety Disorder|Conduct Disorder
Interventions: BEHAVIORAL: Personality-targeted interventions|BEHAVIORAL: Personality-targeted interventions|BEHAVIORAL: Personality-targeted interventions|BEHAVIORAL: Personality-targeted interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Tolerability Study of PCI-24781 in Subjects With Cancer
Status: COMPLETED
Conditions: Lymphoma|Non-Hodgkin's Lymphoma|Hodgkin Disease|Multiple Myeloma|Leukemia|Lymphocytic
Interventions: DRUG: PCI-24781
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Cycles VS Three Cycles Induction Chemotherapy in T1-4N2-3 Locally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Nasopharyngeal Carcinoma
Interventions: DRUG: 2 cycles induction chemotherapy|DRUG: 3 cycles induction chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension
Status: RECRUITING
Conditions: Dental Implant Failed|Prosthesis Failure|Peri-Implantitis
Interventions: PROCEDURE: Implant-supported fixed dental prostheses with cantilever extension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Mechanisms and Health Outcomes of Positive Psychological Intervention
Status: NOT_YET_RECRUITING
Conditions: Well-Being, Psychological
Interventions: BEHAVIORAL: Pathways to Happiness Intervention|BEHAVIORAL: Personal Organization Activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Aerosol Box Use on Healthcare Provider Contamination
Status: COMPLETED
Conditions: Coronavirus|Covid19|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DEVICE: Aerosol Box (Splashguard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relapse Prevention Study in Newly Abstinent Smokers
Status: WITHDRAWN
Conditions: Substance Dependence
Interventions: DRUG: GSK598809|DRUG: Nicotine Replacement Transdermal Patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Hormones and Muscle Protein Synthesis
Status: UNKNOWN
Conditions: Sarcopenia|Muscle Hypotrophy|Muscle Atrophy
Interventions: DRUG: Sustanon 250|DRUG: Zoladex|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Treatment of Patients With High Risk Thymoma
Status: COMPLETED
Conditions: Thymoma
Interventions: DRUG: cisplatin and etoposide|PROCEDURE: Surgical Resection|RADIATION: Concurrent Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of PU-AD in Healthy Subjects
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: PU-AD|DRUG: Placebo|DRUG: Placebo|DRUG: PU-AD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: TPN-101, 100 mg/day|DRUG: TPN-101, 200 mg/day|DRUG: TPN-101, 400 mg/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer
Status: COMPLETED
Conditions: BRCA or HRR+ Mutated Ovarian Cancer Patients
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Personalized Nutritional Intervention on Wound Healing of Cutaneous Ulcers in Diabetics
Status: RECRUITING
Conditions: Foot, Diabetic
Interventions: DIETARY_SUPPLEMENT: Personalized Nutritional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Carcinosarcoma
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Amino Acid-Based hGH Secretagogue on Triiodythyronine
Status: COMPLETED
Conditions: Growth Hormone Treatment|Aging
Interventions: DRUG: Amino acid supplement first day|DRUG: Placebo first day|DRUG: Amino acid supplement second day|DRUG: Placebo second day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tunnel vs. CAF for the Treatment of Multiple Gingival Recessions
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Connective tissue Harvest and CAF|PROCEDURE: Connective tissue Harvest and Tunnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AI Determine Malignancy of GGO on Chest CT
Status: ENROLLING_BY_INVITATION
Conditions: Lung Nodules, Early Lung Cancer, Artificial Intelligence, Chest CT, Minimally Invasive Surgery, Lung Image Analysis Software
Interventions: DIAGNOSTIC_TEST: AI computer-aided detection software
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimus
Status: COMPLETED
Conditions: Kidney Failure|Graft vs Host Disease
Interventions: DRUG: CYCLOSPORINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of NAB001 in the Treatment of Mild to Moderate Onychomycosis of the Toenails
Status: TERMINATED
Conditions: Onychomycosis
Interventions: DRUG: NAB001|DRUG: Vehicle alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Zihua Wenfei Granules in Treatment of Postinfectious Cough (Wind-cold Invading Lungs Syndrome)
Status: RECRUITING
Conditions: Cough
Interventions: DRUG: Zihua Wenfei Zhisou Granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Dronedarone for the Control of Ventricular Rate in Japanese Patients With Permanent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: DRONEDARONE (SR33589)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Thoracotomy Closure Study
Status: COMPLETED
Conditions: Post Thoracotomy Pain Syndrome
Interventions: PROCEDURE: Pericostal Closure Technique|PROCEDURE: Intracostal Closure Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of the Interferential Current to the Pilates Method in the Treatment of Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Chronic Nonspecific Low Back Pain
Interventions: DEVICE: Electrotherapy|DEVICE: Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprafascial Vancomycin Powder for Prevention of Surgical Site Infections After Instrumented Posterior Spinal Fusion
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Various Bariatric Surgical Procedures on Intestinal Triglyceride-rich-lipoprotein (TRL) Metabolism in Obese Patients
Status: COMPLETED
Conditions: Obese Patients|Production Rates of These TRL Before and After the Bariatric Surgery|Cardiovascular Diseases
Interventions: PROCEDURE: Surgical and medical procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: R21 Roche: 3-Way Tau Tracers in AD
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: [18F]RO-948|DRUG: 18F-MK6240|DRUG: 18F-GTP1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hemodialysis Adequacy Using a Heparin-grafted Dialyzer and a Citrate-enriched Dialysate
Status: COMPLETED
Conditions: Kidney Diseases|Hemodialysis Complication|End Stage Renal Disease
Interventions: DEVICE: EvoCit|DEVICE: EvoHep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Comorbid Insomnia in Transdiagnostic Internet-Delivered Cognitive Behaviour Therapy
Status: COMPLETED
Conditions: Insomnia|Anxiety|Depression
Interventions: BEHAVIORAL: Transdiagnostic Internet-delivered Cognitive Behaviour Therapy|BEHAVIORAL: Brief Internet-Delivered Cognitive Behaviour Therapy for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serum Concentrations, Physical and Psychological Well-being in Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: OTHER: Body composition|OTHER: Physical activity level|OTHER: Musculoskeletal pain intensity|OTHER: Quality of life|OTHER: Psychological Well-Being|DIAGNOSTIC_TEST: Blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Cycling then running|OTHER: Running then cycling|OTHER: Inotropy|OTHER: Resting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Silicon Microsieve Device vs Cell Surface Marker-based Platform for the Isolation of Pancreatic Cancer CTCs
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DEVICE: Microsieve device|DEVICE: Cell surface marker-based platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria|PNH
Interventions: DRUG: BCX9930
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Inflammation in Children With Allergic Rhinitis and Intervention
Status: COMPLETED
Conditions: Allergic Rhinitis|Inflammation|Respiratory Tract Diseases|Hypersensitivity
Interventions: DRUG: Budesonide nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zosuquidar in Combination With Daunorubicin and Cytarabine in Patients Ages 55-75 With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid
Interventions: DRUG: Zosuquidar|DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer
Interventions: DRUG: leuprolide acetate|DRUG: goserelin acetate|DRUG: bicalutamide|DRUG: nilutamide|DRUG: flutamide|DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Skills Training to Augment Compensated Work Therapy (CWT)/VI for Veterans With SMI
Status: COMPLETED
Conditions: Mental Illness|Schizophrenia
Interventions: BEHAVIORAL: Maryland Program for Vocational Effectiveness|OTHER: Supportive Treatment for SMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Operative Ankle Splint Study - Prospective Multi Center Randomized Controlled Trial
Status: COMPLETED
Conditions: Ankle Fractures|Splints
Interventions: PROCEDURE: Splinting (plaster of paris)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Swallowing Evaluation by HRIM in Patients With Cervical Spondylosis
Status: NOT_YET_RECRUITING
Conditions: Upper Esophageal Sphincter Relaxing Pressure
Interventions: OTHER: patients with EAT-10 higher than 3 or frailty questionnaire higher than 2 examined by HRIM|OTHER: patients with EAT-10 lower than 3 or frailty questionnaire lower than 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retinal Microvasculature by Optical Coherence Tomography Angiography During Integrating Physical Activity in Diabetic Subjects.
Status: RECRUITING
Conditions: Diabetes Complications
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography Angiography|OTHER: multidisciplinary care program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Community-based Management of Chronic Obstructive Pulmonary Disease in Nepal
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Behavioural-FCHV Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine Infusion for Major Abdominal Pediatric Surgery
Status: COMPLETED
Conditions: Elective Major Abdominal Surgery
Interventions: DRUG: Lidocaine Infusion|DRUG: saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION