pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neurostimulation for Cognitive Rehabilitation in Stroke
Status: UNKNOWN
Conditions: Stroke|Cognitive Impairment|Cerebral Infarction
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Fixed Dose Study of 323U66 SR in the Treatment of Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: 323U66 SR 150 mg tablet|DRUG: 323U66 SR 150 mg placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Definition Transcranial Direct Current Stimulation Motor Cortex Versus Insula
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: HD tDCS active motor cortex|DEVICE: HD tDCS active insula cortex|DEVICE: HD tDCS sham motor cortex|OTHER: Capsaicin cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) in the Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release (DVS SR)|DRUG: Desvenlafaxine Succinate Sustained-Release (DVS SR)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Assess the Efficacy and Safety of SK3530 in Patients With Erectile Dysfunction and Hypertension
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: SK3530
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Movement of the Sacroiliac (SI) Joint, Comparing Conventional RSA With the Sectra Implant Movement Analysis.
Status: COMPLETED
Conditions: Sacroiliac Instability
Interventions: RADIATION: ASLR; CT; SI joint movement: stright leg raise with 1 kg load|RADIATION: Fig.Four; CT; SI joint movement: One side figure of four position with 1 kg load|RADIATION: Supine; CT; SI joint movement: supine position|RADIATION: ASLR; RSA; SI joint movement: stright leg raise with 1 kg load|RADIATION: Fig.Four; RSA; SI joint movement: One side figure of four position with 1 kg load|RADIATION: Supine; RSA; SI joint movement: supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes
Status: COMPLETED
Conditions: GENITAL HERPES
Interventions: DRUG: Famciclovir|DRUG: Aciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery
Status: UNKNOWN
Conditions: Colon Cancer|Rectal Cancer|Colonic Diverticulosis
Interventions: PROCEDURE: TAP Block|PROCEDURE: Continuous Epidural Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Menthol for the Treatment of Chemotherapy Induced Peripheral Neuropathy
Status: TERMINATED
Conditions: Breast Cancer|Colon Cancer|Neuropathy
Interventions: DRUG: topical menthol|DRUG: placebo lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of Combination of Amlodipine and Zofenopril in Hypertensive Patients Versus Each Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Zofenopril|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Real-time Gated 4DCT|DIAGNOSTIC_TEST: Conventional 4DCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spleen Irradiation With Nanoliposomal Irinotecan Plus 5-FU and Leucovorin in Metastatic Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: nanoliposomal irinotecan|RADIATION: spleen irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF EXTRACORPOREAL CYTOKINE ELIMINATION ON HEMODYNAMIA AND MORTALITY IN CRITICAL PATIENTS
Status: ENROLLING_BY_INVITATION
Conditions: Cytokine Hemadsorption Therapy in Critically Ill Patients Who Have no Microbiological Findings and Develop Vasoplegic Shock
Interventions: PROCEDURE: cytokine hemadsorption therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Epoetin Alfa on Hemoglobin, Symptom Distress, and Quality of Life in Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy|Anemia|Cancer
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on TIL Engineered With Membrane-Binding Cytokine for the Treatment of Advanced Gynecologic Tumors
Status: RECRUITING
Conditions: Advanced Gynecologic Tumors|TIL Engineered With Membrane-Binding Cytokine|Treatment Side Effects|Effects of Immunotherapy
Interventions: BIOLOGICAL: Membrane Bound Cytokine Modified TIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip Surgery
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Hepatitis B Vaccination in HIV-infected Adults
Status: COMPLETED
Conditions: Hepatitis B Vaccine
Interventions: BIOLOGICAL: 60 µg dose hepatitis B vaccine|BIOLOGICAL: 20 µg dose hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of AL-335; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: AL-335 matching placebo|DRUG: AL-335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Participants With Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: GSK525762|DRUG: Placebo|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of FKBP51 in the Identification of Non-adherence to Inhaled Corticosteroids in Difficult Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: inhaled steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chidamide With EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
Interventions: DRUG: Chidamide with EGFR-TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal Anesthesia
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Neostigmine|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis
Status: UNKNOWN
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: Sulindac (drug)|DRUG: VSL#3 (probiotic)|DRUG: Inulin (probiotic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Emotional Awareness and SElf-regulation for Depression in Patients With Hypertension (EASE) Study
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: UPLIFT|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing ABVD vs BEACOPP in Advanced Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Bleomycin|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Procarbazine|DRUG: Prednisone|DRUG: Doxorubicin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Reduction of Distal Forearm Fractures by Pediatric Emergency Medicine Physicians: A Prospective Study
Status: COMPLETED
Conditions: Pediatric Distal Forearm Fractures
Interventions: PROCEDURE: Distal Forearm Fracture Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sucralose, Stevia, Gut Microbiome and Glucose Metabolism
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: OTHER: Sucralose|OTHER: Stevia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Assessing Dosing Time and Calcium and Vitamin D on the Relative BA of 35 mg DR Risedronate Dosed With Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 35 mg risedronate DR tablet|DRUG: 35 mg risedronate DR tablet|DRUG: 35 mg risedronate DR tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMART-ALD - A New Lifestyle Intervention to Improve Quality of Life in Women With X-linked Adrenoleukodystrophy (X-ALD)
Status: COMPLETED
Conditions: X-linked Adrenoleukodystrophy
Interventions: BEHAVIORAL: SMART-ALD|BEHAVIORAL: Waiting list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endometriosis and Chronic Endometritis
Status: COMPLETED
Conditions: Endometriosis|Pelvic Pain|Infertility
Interventions: DIAGNOSTIC_TEST: Endometrial aspiration biopsies for CE diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Improving Cancer Family Caregivers' Knowledge and Communication About Care Options
Status: COMPLETED
Conditions: Family Caregivers
Interventions: OTHER: Managing Cancer Care: A Caregiver's Guide|OTHER: Symptom Management Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)
Status: RECRUITING
Conditions: Primary Brain Tumor|Brain Tumor, Recurrent
Interventions: DRUG: Fluoxetine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Pharmacological Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adults Enhance Parenting Performance?
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: lisdexamfetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: PROCEDURE: Atraumatic Restorative Treatment|OTHER: Silver Diamine Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Integrated Consent Model Study to Compare Two Standard of Care Schedules for Monitoring Cardiac Function in Patients Receiving Trastuzumab for Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: LVEF 3 month|PROCEDURE: LVEF 4 month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Cardiac Valve Disease
Interventions: DIETARY_SUPPLEMENT: Nicotinamide riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study of Phentolamine Mesylate Eye Drops in Patients With Severe Night Vision Disturbances
Status: COMPLETED
Conditions: Decrease in Night Vision|Disturbance; Vision, Loss
Interventions: DRUG: Phentolamine Mesylate Ophthalmic Solution 1%|OTHER: Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: folic acid|DIETARY_SUPPLEMENT: omega-3|DIETARY_SUPPLEMENT: vit B12|OTHER: folic acid placebo|OTHER: omega-3 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fat Based Enteral Nutrition for Blood Glucose Control in ICU
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: OTHER: High Fat Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-week Study to Evaluate RebiSmart™ Suitability for Self Injection in Relapsing Multiple Sclerosis.
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Rebif® New Formulation (RNF) using RebiSmartTM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR-Adaptive Radiation Therapy for Anal Cancer With EScalated-Treatment in a Risk-Optimized Approach
Status: RECRUITING
Conditions: Anal Squamous Cell Carcinoma
Interventions: RADIATION: Radiotherapy - Low risk group|RADIATION: Radiotherapy - Standard risk group|RADIATION: Radiotherapy - Intermediate risk group|RADIATION: Radiotherapy - High risk group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Detection Performance of the N Antigenemia of SARS-CoV-2 in the General Population for the Diagnosis and Screening of COVID-19
Status: UNKNOWN
Conditions: Respiratory Viral Infection
Interventions: DIAGNOSTIC_TEST: Venous and Capillary blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Childhood Acute Lymphoblastic Leukemia|Philadelphia Chromosome, Ph^1^, Absent|B-cell Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: Idarubicin(IDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin Lispro 6 Days Versus Insulin Aspart 6 Days in Pump Use
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin Lispro 6 Day (6D)|DRUG: Insulin Aspart 6 Day (6D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilates Method and Therapeutic Exercise in Children That Play String Instruments
Status: COMPLETED
Conditions: Postural Kyphosis|Postural Lordosis|Postural Low Back Pain
Interventions: OTHER: Pilates Method combined with Therapeutic exercice.|OTHER: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Protocol of Accelerated Rehabilitation Following Surgical Correction of Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis Idiopathic
Interventions: OTHER: Rehabilitation protocol|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Data (RWD) of Ramucirumab Plus Paclitaxel
Status: UNKNOWN
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab and paclitaxel|DRUG: Taxane, irinotecan, or fluoropyrimidine-based single or combined chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Low-Level Laser Therapy on Oxidative Stress Levels...
Status: COMPLETED
Conditions: Hashimoto Thyroiditis|Autoimmune Thyroiditis|Thyroiditis|Thyroid Diseases|Autoimmune Diseases
Interventions: OTHER: Low-Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety in the Combination of Ibuprofen / Loratadine Versus Ibuprofen Versus Loratadine
Status: RECRUITING
Conditions: Common Cold
Interventions: DRUG: Ibuprofen + Loratadine fixed dose|DRUG: Ibuprofen|DRUG: Loratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exemestane in Hormone Receptor Positive High Grade Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Exemestane|OTHER: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: From Uncomplicated Alcoholism to Korsakoff's Syndrome
Status: UNKNOWN
Conditions: Alcoholism|Alcohol Amnestic Disorder
Interventions: BEHAVIORAL: Neuropsychological testing|BIOLOGICAL: blood draw|GENETIC: genetic testing|OTHER: Brain imaging examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of YOUR SUPER Detox Bundle to Improve Perceived Well Being and Promote Adaptation of Healthy Dietary Choices
Status: COMPLETED
Conditions: Eating Habit|Healthy Diet
Interventions: DIETARY_SUPPLEMENT: YOUR SUPER Detox Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess Safety/Tolerability/Efficacy of Gefitinib Versus Docetaxel in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Gefitinib|PROCEDURE: CT or MRI|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Device in Children With Upper Congenital Limb Deficiency
Status: UNKNOWN
Conditions: Upper Limb Deformities, Congenital
Interventions: DEVICE: 3D Printed Myoelectric Prosthetic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis(R) Needle-Free Injection Delivery Device
Status: COMPLETED
Conditions: Hantavirus Pulmonary Infection|Immunisation
Interventions: BIOLOGICAL: Andes virus DNA vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Interventions in Cancer Patients Treated With Immune Checkpoint Inhibitors
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: DIETARY_SUPPLEMENT: High-fermented food|DIETARY_SUPPLEMENT: High fiber supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn How the Body Processes Spironolactone and Hydrochlorothiazide Film Coated Tablets Manufactured at Two Sites: Viatris and Neolpharma
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Spironolactone/Hydrochlorothiazide (25 mg/25 mg) film coated tablets from Viatris|DRUG: Spironolactone/Hydrochlorothiazide (25 mg/25 mg) film coated tablets from Neolpharma.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3
Status: NOT_YET_RECRUITING
Conditions: Cryptococcal Meningitis
Interventions: DRUG: MAT2203|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-157 in Healthy Volunteers and in Participants With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: ABBV-157|DRUG: Placebo for ABBV-157
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19
Status: COMPLETED
Conditions: COVID|Thrombosis|Pulmonary Embolism|Deep Vein Thrombosis
Interventions: DRUG: Enoxaparin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of TAS-303 in Female Patients With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: TAS-303 18mg single-dose|DRUG: Placebo 18mg single-dose|DRUG: TAS-303 9mg single-dose|DRUG: Placebo 9mg single-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Study of Fixed Versus Flexible of Gonadotropin-releasing Hormone Antagonist Protocol
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Follitropin Beta|DRUG: Ganirelix|DRUG: Ganirelix|DRUG: rhCG|DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials for Elderly Patients With Multiple Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Congestive Heart Failure (CHF)|Sleep Disordered Breathing (SDB)
Interventions: DEVICE: CHROMED monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Efficacy and Safety of WID-RGC20(Cariprazine) in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: WID-RGC20(Cariprazine) 3mg/day|DRUG: WID-RGC20(Cariprazine) 6mg/day|DRUG: Placebo for WID-RGC20(Cariprazine) 3mg/day or 6mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D-PCT Combined With CT-guided Radioactive I-125 Seed Implantation in the Treatment of Head and Neck Tumors
Status: RECRUITING
Conditions: Malignant Tumor of Head and/or Neck
Interventions: RADIATION: Radioactive Iodine-125 Seeds Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Serelys PMS on Symptoms of PMS
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Serelys PMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-day (3) In-patient Evaluation of Intradermal Versus Subcutaneous Basal and Bolus Insulin Infusion
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: Subcutaneous delivery via Medtronic Quick-Set|DEVICE: Intradermal delivery via the BD Research Catheter Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Electroacupuncture and Acupuncture in Postmenopausal Women With Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder|Menopause
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Novel Antiretrovirals in Participants With HIV-1
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: bavtavirine|DRUG: B/F/TAF|DRUG: Standard of Care (Substudy 01)|DRUG: GS-1720|DRUG: Standard of Care (Substudy 02)|DRUG: GS-6212|DRUG: Standard of Care (Substudy 03)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Biomarkers in Muscle Pain and Joint Pain in Patients With Solid Tumors Receiving Paclitaxel
Status: TERMINATED
Conditions: Arthralgia|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instant Total Contact Cast to Heal Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: Total Contact Cast|DEVICE: Instant Total Contact Cast (ITCC)|DEVICE: Removable Cast Walker (RCW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis|Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Enzyme containing lozenge|DIETARY_SUPPLEMENT: Placebo lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tacrolimus for the Treatment of Systemic Lupus Erythematosus With Membranous Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis|Lupus Erythematosus, Systemic
Interventions: DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Uterine Cervical Dysplasia
Interventions: DRUG: placebo|DRUG: A007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: cytarabine|DRUG: etoposide|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact on Therapeutic Effect and Tolerance of Treatment for Patients With Hepatocellular Carcinoma in Transcatheter Arterial Chemoembolization (TACE) of Dexamethasone Application: A Random, Double-blind, Controlled, Clinical Trial.
Status: UNKNOWN
Conditions: HepatoCellular Carcinoma
Interventions: DRUG: Dexamethasone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat (SAHA) in Uterine Sarcoma
Status: TERMINATED
Conditions: Leiomyosarcoma|Endometrial Stromal Tumors|Carcinosarcomas Uterine
Interventions: DRUG: Vorinostat Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Total Intravenous Anesthesia Following Cancer Surgery, TIVACS Study
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Anesthesia Procedure|DRUG: General Anesthesia Procedure|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Easy is it to Identify the Cricothyroid Membrane in Children? Can Ultrasound Imagine be Used to Aid Identification?
Status: COMPLETED
Conditions: Cricothyroidotomy
Interventions: OTHER: Palpation|OTHER: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Completion and Acceptability of Treatment Across Primary Care and the commUnity for Latent Tuberculosis
Status: COMPLETED
Conditions: Latent Tuberculosis
Interventions: OTHER: Community/Primary Care|OTHER: Hospital/TB Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of XNW3009 in Health Subject
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: XNW3009|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maladaptive Anger Treatment
Status: RECRUITING
Conditions: Anger|Intermittent Explosive Disorder|Emotional Distress|Aggression|Violence
Interventions: BEHAVIORAL: Cognitive Behavioral Affective Therapy|BEHAVIORAL: Emotional Discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Combination of Low-Level Laser and Light-Emitting Diodes Enhance Stability of Dental Implants?
Status: COMPLETED
Conditions: Dental Implant Healing
Interventions: DEVICE: Low-Level Laser and Light-Emitting Diodes|DEVICE: Dental implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Study the Effects of Revamilast in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Revamilast|DRUG: Revamilast|DRUG: Revamilast|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
Status: RECRUITING
Conditions: Osteomyelitis|Diabetic Foot Osteomyelitis
Interventions: BIOLOGICAL: Phage Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibodutant for Relief of Irritable Bowel Syndrome (IRIS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Ibodutant|DRUG: Ibodutant|DRUG: Ibodutant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemophilia Inhibitor Clinical Trials (INHIBIT) Platform
Status: WITHDRAWN
Conditions: Severe Hemophilia A
Interventions: DRUG: Eloctate Prophylaxis|DRUG: Emicizumab Prophylaxis|DRUG: Eloctate ITI plus Emicizumab|DRUG: Eloctate ITI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of CD-NP in the Treatment of Patients With Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: CD-NP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: donor FMT|OTHER: Placebo FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH)|DEVICE: Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Antidepressant Effects of DMT in Patients With Depression
Status: COMPLETED
Conditions: Depressive Disorder|Depression, Unipolar
Interventions: DRUG: N,N-Dimethyltryptamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Single Doses of 10 mg NRL001 Applied as a Suppository to the Anal Canal or Rectum
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: NRL001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TCD601 in the Induction of Tolerance in de Novo Liver Transplantation
Status: RECRUITING
Conditions: Liver Transplantation
Interventions: BIOLOGICAL: TCD601|BIOLOGICAL: Cyclophosphamide|DRUG: TAC|DRUG: MMF|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study on Targeted CD19 CAR-T Therapy for Autoimmune Diseases
Status: RECRUITING
Conditions: SLE (Systemic Lupus)|Systemic Sclerosis|ANCA Associated Vasculitis|Idiopathic Inflammatory Myopathies|Sjogren's Syndrome|Autoimmune Diseases
Interventions: DRUG: RD06-04 CART Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protocol: Reconstruct the Pelvic Peritoneum Using BPF
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Standard laparoscopic ELAPE with pelvic peritoneal floor reconstruction using bladder peritoneum flap are to performed.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion Regulation and Pain in Children With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Reapprasial Condition|BEHAVIORAL: Reassurance Condition|BEHAVIORAL: Distraction Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of IV Calcium to Prevent Diltiazem-related Hypotension
Status: COMPLETED
Conditions: Atrial Fibrillation|Rapid Ventricular Response|Hypotension Drug-Induced
Interventions: DRUG: Sodium chloride|DRUG: 90 mg of calcium|DRUG: 180 mg Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Plantar Fascia Release in Cases of Chronic Resistant Plantar Fasciopathy
Status: UNKNOWN
Conditions: in Cases of Chronic Resistant Plantar Fasciopathy
Interventions: PROCEDURE: Endoscopic plantar fascia release in cases of chronic resistant plantar fasciopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block With Magnesium Sulfate Added to Local Anesthetic in Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Magnesium Sulfate|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer Patients With Detectable PSA Following Prostatectomy
Interventions: DRUG: Everolimus (RAD001)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Certolizumab in Combination With Chemotherapy for Patients With Stage IV Lung Adenocarcinomas
Status: COMPLETED
Conditions: Stage IV Lung Adenocarcinoma
Interventions: DRUG: Certolizumab|DRUG: cisplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft Acute Kidney Injury: Vitamin B3 to Facilitate Renal Recovery In the Early Life of a Transplant
Status: COMPLETED
Conditions: Delayed Graft Function
Interventions: DRUG: Nicotinamide treatment|DRUG: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability of Self-sampling for Cervical Cancer Screening
Status: UNKNOWN
Conditions: HPV-Related Cervical Carcinoma|Self-sampling|Cervical Cancer Screening
Interventions: DEVICE: Explanation on how to use self-sampling device and training in the screening visit.|OTHER: Only explanation on how to use self-sampling device.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: Stealth Station|DEVICE: PoleStar N20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: KL7016 900mg|DRUG: KL7016 600mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coronavirus Disease 2019 (COVID-19) Antibody Plasma Research Study in Hospitalized Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: High-titer Convalescent COVID-19 Plasma (CCP1)|BIOLOGICAL: Standard-titer Convalescent COVID-19 plasma (CCP2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of a Topical Steroid to a Topical Retinoid in Acne Patients
Status: UNKNOWN
Conditions: Acne
Interventions: DRUG: Triamcinolone|DRUG: Tretinoin|DRUG: Emollient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema
Status: RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: 8 mg aflibercept (BAY 86-5321) (High Dose)|DRUG: 2 mg aflibercept (EYLEA, BAY 86-5321)|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma, Complex Decongestive Physiotherapy and Low Level Laser in Treatment of Lower Extremity Lymphoedema
Status: COMPLETED
Conditions: Lower Extremity Lymphedema
Interventions: PROCEDURE: PRP method|PROCEDURE: Low Level Laser|PROCEDURE: Complex Decongestive Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Faithful Response to COVID-19 Project
Status: COMPLETED
Conditions: A Multilevel, Tailored COVID-19 Testing Condition|A Nontailored COVID-19 Testing Control Condition
Interventions: BEHAVIORAL: A Faithful Response to COVID-19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Performance and Safety of Joline® Kyphoplasty Single Balloon Catheter Allevo vs. Quattroplasty Double-Balloon Catheter Stop'n GO With BonOs® Inject Bone Cement
Status: UNKNOWN
Conditions: Vertebral Compression Fracture
Interventions: DEVICE: Kyphoplasty Single Balloon Catheter Allevo|DEVICE: Quattroplasty Double Balloon Catheter Stop'n GO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Music Therapy Along With Task-Oriented Training on Patients With Chronic Stroke
Status: COMPLETED
Conditions: Hemiplegia
Interventions: OTHER: Routine Physiotherapy and Task-oriented Training|OTHER: Music Therapy and Task oriented Training with Routine Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ravulizumab (ALXN1210) in Children and Adolescents With Paroxysmal Nocturnal Hemoglobinuria
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: BIOLOGICAL: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nutritional Intervention in Participants With Eating Disorders.
Status: COMPLETED
Conditions: Eating Disorders|Binge-Eating Disorder|Binge Eating Disorder Associated With Obesity|Eating Behavior|Eating Disorder
Interventions: BEHAVIORAL: Mindful Eating
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Transcutaneous Electrical Nerve Stimulation in Heart Failure
Status: UNKNOWN
Conditions: Improvement of Cardiovascular Autonomic Control|Reduction of Levels of Catecholamines
Interventions: OTHER: transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partnership for Research on Ebola Vaccines in Liberia (PREVAIL)
Status: COMPLETED
Conditions: Ebola Virus
Interventions: BIOLOGICAL: VSVG-ZEBOV|BIOLOGICAL: ChAd3-EBO Z|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION