pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Translation, Validity, and Reliability of the Foot Posture Index (FPI-6) - Turkish Version
Status: COMPLETED
Conditions: Foot Deformities|Pes Planus|Hallux Valgus|Metatarsalgia|Feet Pes Planus (Flatfoot)
Interventions: DIAGNOSTIC_TEST: Foot Posture Index (FPI-6)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With MSI/dMMR Metastatic Colorectal Cancer (CORESIM)
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|Microsatellite Instability-High Colorectal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fluorescence Cholangiography During Cholecystectomy - a RCT
Status: COMPLETED
Conditions: Cholecystitis|Gallstones
Interventions: DRUG: Indocyanine green|DEVICE: Near-infrared illumination|DRUG: Urografin|RADIATION: X-ray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase II Study of Oral Sapacitabine in Patients With Advanced Cutaneous T-cell Lymphoma
Status: TERMINATED
Conditions: Cutaneous T-cell Lymphoma (CTCL)
Interventions: DRUG: Sapacitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: sintiliman plus LDRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irbesartan/Amlodipine in Hypertensive Patients Uncontrolled on Irbesartan 150 mg Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: irbesartan/amlodipine|DRUG: irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CompuFlo® Technology in Thoracic Epidural Space Identification
Status: NOT_YET_RECRUITING
Conditions: Thoracic Epidural Space Identification
Interventions: PROCEDURE: Loss of resistance (LOR) technique|DEVICE: CompuFlo® technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Abdominal Hallowing on Coactivation of Lower Extremity Muscles in Patients With Lumbal Disc Herniation
Status: COMPLETED
Conditions: Disk Herniated Lumbar|Coordination Lack|Muscle Weakness
Interventions: BEHAVIORAL: Abdominal Hollowing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Efficacy of Vitamin D-fortified Oil in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: fortified oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Xofluza-Wearables Feasibility-Study
Status: RECRUITING
Conditions: Infection, Coronavirus|Infections|Influenza|Transplant|Infection Viral
Interventions: DRUG: Baloxavir Marboxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events, Change in Disease Activity, Movement of Oral ABBV-623 and ABBV-992 Tablets in the Body of Adult Participants With B-cell Cancers
Status: TERMINATED
Conditions: B-cell Lymphoma
Interventions: DRUG: ABBV-623|DRUG: ABBV-992
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infection|HIV Infections
Interventions: GENETIC: SB-728-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients
Status: COMPLETED
Conditions: Condyloma
Interventions: DRUG: AP611074 5% gel|DRUG: AP611074 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Concomitant Camrelizumab With Chemoradiation for Locally Advanced Head and Neck Cancer
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: BIOLOGICAL: Camrelizumab|DRUG: Cisplatin|RADIATION: IMRT or VMAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Diode Laser and Subgingival Air Polishing With Erythritol in Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: ultrasonic tips and Gracey curettes, airflow with erythritol and diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Fish Oil Supplementation in Treatment of Intrahepatic Cholestasis of Pregnancy
Status: WITHDRAWN
Conditions: Intrahepatic Cholestasis of Pregnancy
Interventions: DIETARY_SUPPLEMENT: Fish Oil Supplement Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topical 0.2% Xanthan Gum in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: carboxymethylcellulose|DEVICE: xanthan gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tissue and Serum Level of NLRP1, NLRP3 and Il-18 in Early Stages of mf Patients
Status: NOT_YET_RECRUITING
Conditions: Early Disease Onset
Interventions: DEVICE: Puva (psoralin and uva )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of a Brief Online Mindfulness and Self-Compassion Intervention (Mind-OP+) to Increase Connectedness
Status: COMPLETED
Conditions: Depression|Stress|Social Isolation|Anxiety
Interventions: BEHAVIORAL: Mind-OP+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralymphatic Immunotherapy for House Dust Mite, Dog, and Cat Allergy Using Tyrosine S® in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: ILIT with extract of causal allergen|BIOLOGICAL: ILIT with normal saline|DRUG: Rescue medication for allergic rhinitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of "Workplace Health Promotion Program" on Pain, Fatigue, Stress in Nurses
Status: COMPLETED
Conditions: Nurses|Work-Related Stress Disorder|Pain|Fatigue
Interventions: OTHER: WORKPLACE HEALTH PROMOTION PROGRAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Hemostatic Effect of Lyostypt® Versus Surgicel® in Arterial Bypass Anastomosis
Status: COMPLETED
Conditions: Peripheral Vascular Diseases|Hemostasis
Interventions: DEVICE: Lyostypt® AND Surgicel®|DEVICE: Lyostypt®|PROCEDURE: Surgicel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Dietary Buglossoides Oil
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Ahiflower oil|DIETARY_SUPPLEMENT: Flaxseed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Niraparib|DRUG: Leuprolide|DRUG: Abiraterone Acetate|RADIATION: Stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC)
Status: NOT_YET_RECRUITING
Conditions: Unresectable Pancreatic Cancer
Interventions: DRUG: NRT6008 Injection + Systematic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POC Study to Evaluate BSI-045B Monotherapy and BSI-045B add-on Therapy With Dupilumab in Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: BSI-045B|DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of KLU156 in Adults and Children ≥ 5 kg Body Weight With Uncomplicated P. Falciparum Malaria
Status: RECRUITING
Conditions: Uncomplicated Plasmodium Falciparum Malaria
Interventions: DRUG: KLU156|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamics Effects of Fludrocortisone on the Pressor Response to Noradrenaline Septic Shock Patients
Status: SUSPENDED
Conditions: Septic Shock
Interventions: DRUG: Fludrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Ziprasidone Study for Psychosis Treatment in Adolescents
Status: COMPLETED
Conditions: Schizophreniform Disorder|Schizoaffective Disorder|Psychosis|Depressive Disorder, Major|Bipolar Disorder
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pBFS-guided Dual-target cTBS for Aphasia After Stroke
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: active continuous Theta Burst Stimulation|DEVICE: sham continuous Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Feasibility and Preliminary Impact of a mHealth App on Reducing STI Risk in Black MSM PrEP Users
Status: RECRUITING
Conditions: STI|Sexually Transmitted Diseases|Pre-exposure Prophylaxis
Interventions: DEVICE: App Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Anterior Resection Syndrome
Interventions: DEVICE: Sacral NeuroModulation|DEVICE: Trans-Anal Irrigation|OTHER: Optimised Conservative Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Genetic Association of Glucocorticoid Receptor Gene Polymorphisms With Binge Eating
Status: COMPLETED
Conditions: Binge-Eating Disorder|Eating Disorders|Obesity|Diabetes Type 2|Adolescent Behavior
Interventions: DIAGNOSTIC_TEST: BED Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: HIV Prevention and Trauma Treatment in Men Who Have Sex With Men and Who Have a History of Sexual Abuse
Status: COMPLETED
Conditions: Risk Reduction
Interventions: BEHAVIORAL: Information-motivation-behavior skills and cognitive processing therapy|BEHAVIORAL: Pre and Post HIV-Test Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Hypertension|Neurofibromatosis 1|Blood Pressure
Interventions: OTHER: Group 1. Standard Home Blood Pressure Measurement|OTHER: Group 2. Hypnosis script prior to home blood pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glucose Control in Pre-Diabetic Renal Transplant Patients
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Kidney Transplantation
Interventions: DRUG: Vildagliptin|DRUG: Pioglitazone|BEHAVIORAL: Life-Style Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Liver Intraoperative Imaging With SonoVue®
Status: COMPLETED
Conditions: Liver Metastases From Colorectal Primary Cancer
Interventions: DEVICE: Contrast-enhanced intraoperative ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Chemotherapy Plus ddI or ddC in the Treatment of AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate|DRUG: Doxorubicin hydrochloride|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Safety And Pharmacokinetic Study of Setrobuvir Alone and In Combination With Ritonavir-Boosted Danoprevir in Subjects With Mild Hepatic Impairment Compared to Healthy Controls
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: ritonavir|DRUG: setrobuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD
Status: COMPLETED
Conditions: Congenital Heart Defects|Down Syndrome|Gross Motor Development Delay
Interventions: DIAGNOSTIC_TEST: evaluation of cardiopulmonary parameters, gross motor development and hand grip strength
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Sciatic nerve anesthesia blockade at bifurcation.|PROCEDURE: Sciatic nerve blockade 2 cm beyond the bifurcation|DRUG: Levobupivacaine 0.5%: 20 ml|DEVICE: Portable Ultrasound Machine: Sonosite, M-Turbo, Bothell, WA|DEVICE: Insulated Needle, (Stimuplex; Braun, Melsungen, Germany)|DRUG: supplemental oxygen|DRUG: Midazolam|DRUG: Intravenous analgesics|PROCEDURE: Saphenous nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Anterior Segment Changes After Pars Plana Vitrectomy (PPV) and Silicone Oil (SO) Tamponade, Anterior Segment OCT (AS-OCT) Study.
Status: NOT_YET_RECRUITING
Conditions: ASOCT Changes After Vitrectomy and Silicone Oil Injection
Interventions: PROCEDURE: vitrectomy and silicone oil injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome
Status: TERMINATED
Conditions: Healthy Participants|Primary Sjögren's Syndrome
Interventions: BIOLOGICAL: BMS-986325|OTHER: Placebo for BMS-986325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Patch Applied To The Skin
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: varenicline free base patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Esketamine/Propofol and Methohexital Anesthesia for ECT
Status: RECRUITING
Conditions: ECT|Depression
Interventions: DRUG: Methohexital|DRUG: Ketofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium Valproate-loaded Nanospanlastics in Patchy Alopecia Areata in Comparison to Topical Steroids
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: the optimized sodium valproate-loaded nanospanlastic dispersion|DRUG: mometasone furoate lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 3D-printed Reconstruction System in Size of Left DLT
Status: NOT_YET_RECRUITING
Conditions: Cancer of Lung|Lung Isolation
Interventions: OTHER: 3D reconstruction|OTHER: traditional method for selecting double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz
Status: COMPLETED
Conditions: Hyperlipidemia|HIV
Interventions: DRUG: Pitavastatin|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Metyrapone and Oxazepam Combination Product (EMB-001) and Cocaine
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: EMB-001|DRUG: Placebo|DRUG: Cocaine IV|DRUG: Saline IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Adhesive Wafer Design on Fit to the Body
Status: COMPLETED
Conditions: Ostomy - Ileostomy or Colostomy
Interventions: DEVICE: Test A|DEVICE: Test B|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Glue Saphenous Vein Ablation With Compression Versus Compression Alone in the Healing of the Venous Ulcer
Status: UNKNOWN
Conditions: Venous Leg Ulcer
Interventions: PROCEDURE: Standard therapy arm|PROCEDURE: Early endovenous glue embolization arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Status: RECRUITING
Conditions: Thumb Osteoarthritis
Interventions: OTHER: Immobilization for 2-weeks postoperative|OTHER: Immobilization for 6-weeks postoperative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adibelimab, Famitinib and Chemotherapy for Advanced NSCLC After PD-1 Inhibitor Failure
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Adibelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracochlear Dexamethasone Application During Cochlear Implantation for Preserving Cochlear Cells
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DRUG: Intracochlear Dexamethasone|DRUG: Intratympanic Dexamethasone|DRUG: No additional drugs(control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Sevoflurane|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency
Status: COMPLETED
Conditions: Sphingomyelin Lipidosis
Interventions: DRUG: Olipudase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Derived AC 133+ and Mono-Nuclear Cells (MNC) Implantation in Myocardial Infarction (MI) Patient
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: BIOLOGICAL: AC133|BIOLOGICAL: MNC|BIOLOGICAL: CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Mobile Application for HBB Prompt Study
Status: UNKNOWN
Conditions: Birth Asphyxia|Neonatal Death
Interventions: BEHAVIORAL: HBB Prompt|BEHAVIORAL: Low-Dose High Frequency training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions
Status: TERMINATED
Conditions: Nevus|Racial Melanosis|Primary Acquired Melanosis|Conjunctival Malignant Melanoma
Interventions: PROCEDURE: HRT III with Non-Contact Cornea Rostock Module
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suspended Overlength Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Status: UNKNOWN
Conditions: Bile Duct Stricture
Interventions: PROCEDURE: 26cm suspended overlength biliary stents|PROCEDURE: 30cm suspended overlength biliary stents|PROCEDURE: ordinary plastic biliary stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Accuracy of Brain Biological Electrical Impedance Tomography Screen for Supratentorial Tumors
Status: UNKNOWN
Conditions: Brain Tumor|Brain Edema
Interventions: DEVICE: brain biological electrical impedance tomography|DEVICE: MRI/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of Patient Preoperative Preps In-vivo
Status: COMPLETED
Conditions: Surgical Skin Preparation
Interventions: DRUG: CHG/IPA Surgical skin preparation|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Application of CLCVP Technique in Early Intervention of CSA-AKI
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury
Interventions: COMBINATION_PRODUCT: controlled low central venous pressure technique (CLCVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The OneFreeze Study
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Atrial fibrillation catheter ablation using the Medtronic Arctic Front Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PRONTO: Obstetric and Neonatal Emergency Training Program: A Cluster-Randomized Trial to Measure Impact
Status: COMPLETED
Conditions: Pregnancy Related Complications
Interventions: OTHER: PRONTO training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Nadolol Plus Isosorbide Mononitrate Versus Carvedilol for the Prevention of Variceal Rebleeding
Status: COMPLETED
Conditions: Variceal Rebleeding
Interventions: DRUG: carvedilol|DRUG: nadolol + ISMN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/NSABP B-63)
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Sacituzumab govitecan-hziy (SG)|DRUG: Pembrolizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Physical Activity During Sitting on Glycemic Control and Vascular Function in Obese Individuals
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Glucose|BEHAVIORAL: Fidgetting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine Versus Dexmedetomidine for Prevention of Postoperative Delirium
Status: COMPLETED
Conditions: Emergence Delirium
Interventions: DRUG: Ketamine Hcl 50Mg/Ml Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected Children
Status: COMPLETED
Conditions: Human Immunodeficiency Virus 1
Interventions: DRUG: Darunavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin
Status: RECRUITING
Conditions: Ovarian Cancer|Hyperthermic Intraperitoneal Chemotherapy|Paclitaxel
Interventions: DRUG: Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Carisbamate in the Treatment of Nerve Pain in Diabetics
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Pregabalin 300 mg/d|DRUG: Carisbamate 800 mg/d|DRUG: Carisbamate 1,200 mg/d|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Study To Evaluate the Long-Term Safety and Effectiveness of 60 mg Versus 120 mg of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Paracetamol and Patent Ductus Arteriosus (PDA)
Status: UNKNOWN
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Paracetamol|DRUG: NSAID|DRUG: D5W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP
Status: COMPLETED
Conditions: Immune Thrombocytopenia (ITP)
Interventions: DRUG: Eltrombopag|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Adoptive Immunotherapy in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndromes That Relapsed After Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic allogeneic lymphocytes|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: cytarabine|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF VIRTUAL REALITY APPLICATIONS ON SITTING BALANCE IN HEMIPLEGIA: A RANDOMIZED CONTROLLED STUDY
Status: RECRUITING
Conditions: Hemiplegia
Interventions: DEVICE: Becure GmbH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-Cell Lymphoma|Post-transplant Lymphoproliferative Disorder|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: lenalidomide|DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Chronic Kidney Disease Stage 5|ESRD
Interventions: DRUG: AZD1722 (in-patient)|DRUG: Placebo (in-patient)|DRUG: AZD1722 (out-patient)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Benzocaine for Pain Relief in Children Presenting With Acute Otitis Media
Status: COMPLETED
Conditions: Pain|Acute Otitis Media
Interventions: DRUG: Benzocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Skeletal-muscle Microbiopsy Technique With Dynamic Proteomic Measurement in Healthy Male Volunteers
Status: COMPLETED
Conditions: Cachexia
Interventions: DRUG: Deuterated Water|DRUG: Testosterone enanthate|DRUG: Placebo to match testosterone enanthate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: ABY-039|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)
Interventions: DRUG: Odronextamab|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone/prednisolone|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Standardized Training in the Diagnosis of Interstitial Lung Disease by Transbronchial Lung Cryobiopsy
Status: NOT_YET_RECRUITING
Conditions: Transbronchial Lung Cryobiopsy
Interventions: OTHER: simulated training|OTHER: traditional bedside teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19)
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome|Mechanical Ventilation|SARS (Severe Acute Respiratory Syndrome)
Interventions: OTHER: EIT-Group|OTHER: ARDSNet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Opioid-Induced Respiratory Depression (OIRD)
Status: COMPLETED
Conditions: Respiratory Depression
Interventions: DRUG: Remifentanil|DRUG: Oxygen|DRUG: Carbon dioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy
Status: TERMINATED
Conditions: Acute Ischemic Stroke|Large Vessel Occlusion|Thrombectomy|Thrombosis
Interventions: PROCEDURE: Balloon guide catheters (BGCs)|PROCEDURE: Standard guide catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial
Status: NOT_YET_RECRUITING
Conditions: Clonal Cytopenia of Undetermined Significance|CCUS Clonal Cytopenia of Undetermined Significance
Interventions: DRUG: Enasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Cardiovascular Disease|Glucose Metabolism Disorders
Interventions: DRUG: Ramipril|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles
Status: UNKNOWN
Conditions: Infertility, Female|Infertility of Uterine Origin|Implantation; Placenta
Interventions: DIAGNOSTIC_TEST: transvaginal ultrasound,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lapatinib in Combination With Weekly Paclitaxel in Patients With ErbB2 Amplified Advanced Gastric Cancer
Status: COMPLETED
Conditions: Neoplasms, Gastrointestinal Tract
Interventions: DRUG: Lapatinib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paced Electrogram Feature Analysis (PEFA) for Ablation Targeting in Ischaemic Ventricular Tachycardia
Status: RECRUITING
Conditions: Ischemic Ventricular Tachycardia (VT)
Interventions: PROCEDURE: PEFA VT ablation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Compare Long-term Efficacy and Safety of an Aliskiren Based Regimen to a Hydrochlorothiazidebased Treatment Regimen With Optional Addition of Amlodipine
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Vascular Inflammation in Type-2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Liraglutide|DRUG: Placebo (for liraglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimal Frequency of High-Intensity Interval Training for Centrally Obese Adults
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Once-Weekly HIIT|BEHAVIORAL: Thrice-Weekly HIIT|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
Status: UNKNOWN
Conditions: Surgery of Abdominoplasty With Flank Liposuction
Interventions: PROCEDURE: Transverse abdominal plan block|PROCEDURE: Continuous wound infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Blood Sampling|DIAGNOSTIC_TEST: Microdialysis|DIAGNOSTIC_TEST: Neuropsychological tests|DIAGNOSTIC_TEST: MRI (advanced)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arthroscopy of the Temporomandibular Joint. On Jaw Mobility, Pain and HRQoL
Status: COMPLETED
Conditions: Arthroscopic Surgery|Temporomandibular Joint|Health-Related Quality Of Life|Follow-Up Studies|Observational
Interventions: PROCEDURE: Arthroscopic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome, Adult|Sars-CoV2
Interventions: DEVICE: Hypothermia|DRUG: Neuromuscular Blocking Agents|DEVICE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efectiveness of a Brief Protocol by a Low (6%) Concentration Gel Peroxide Hydrogen of Teeth Bleaching
Status: COMPLETED
Conditions: Tooth Discoloration
Interventions: DRUG: peroxide gel tooth bleaching 6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 1% Lidocaine Paracervical Block for Endometrial Biopsy
Status: NOT_YET_RECRUITING
Conditions: Endometrial Biopsy
Interventions: DRUG: Lidocaine 1% Injectable Solution|DRUG: Saline|OTHER: Capped needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease, Beta Thalassemia Intermedia
Interventions: DIAGNOSTIC_TEST: RNA Binding Protein Pumilio1 (PUM1) Expression by reverse transcriptase quantatative PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study Evaluating the Safety and Efficacy of SKG0201 Injection in Patients With Spinal Muscular Atrophy Type 1
Status: RECRUITING
Conditions: Spinal Muscular Atrophy 1
Interventions: GENETIC: SKG0201 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: AVE5530|DRUG: placebo|DRUG: ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer With Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial
Status: RECRUITING
Conditions: Weight Gain
Interventions: OTHER: weight gain each group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
Status: UNKNOWN
Conditions: Bone Metastases|Radiotherapy Side Effect
Interventions: RADIATION: Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Of TeleGenetics Versus Usual Care To Increase Access To Cancer Genetic Services
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Penn genetic counselors provides counseling and test results disclosure by videoconferene to patient at community site|BEHAVIORAL: Penn genetic counselor provides counseling and test results disclosure by telephone to patient at community site|BEHAVIORAL: Patient receives written information on how to find genetic services in their area
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Intravascular Penetration With Curved Needle and Straight Needle During S1 STE
Status: RECRUITING
Conditions: S1 Transforaminal Epidural Injection
Interventions: OTHER: needle type
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of E6007 in Japanese Patients With Moderate Active Ulcerative Colitis
Status: COMPLETED
Conditions: Moderate Active Ulcerative Colitis
Interventions: DRUG: E6007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: D/ChAd63-CA|BIOLOGICAL: D/ChAd63-CAT|OTHER: Infectivity Control (IC) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Web-Based Cognitive Behavioral Stress Management for Latino Sexual Minority Men Living With HIV and Cancer
Status: RECRUITING
Conditions: HIV/AIDS|Cancer
Interventions: BEHAVIORAL: Cognitive behavioral stress management|BEHAVIORAL: Culturally-tailored cognitive behavioral stress management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Compensated Cirrhosis|Nonalcoholic Steatohepatitis
Interventions: DRUG: Obeticholic acid (10 mg)|DRUG: Obeticholic acid (10 mg to 25 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of tDCS in Help for Supporting Alcohol Abstinence
Status: RECRUITING
Conditions: Alcoholic Intoxication
Interventions: DEVICE: Active tDCS stimulations|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Revatio Portal-Pulmonary Arterial Hypertension Trial
Status: TERMINATED
Conditions: Portopulmonary Hypertension
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-Flow Nasal Cannula on IVC Measurements Using Point of Care Ultrasound
Status: WITHDRAWN
Conditions: Fluid Overload
Interventions: DEVICE: high flow nasal cannulae
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients
Status: RECRUITING
Conditions: SMA
Interventions: PROCEDURE: Robotically Assisted Locomotion|PROCEDURE: Robotically Assisted Verticalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE