pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intrathecal Clonidine in Cesarean Section May Lead to Worse Blood Gas Results in the Newborns
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Intrathecal Clonidine|DRUG: Intravenous Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer
Status: TERMINATED
Conditions: Locally Advanced Rectal Adenocarcinoma|Metastatic Rectal Adenocarcinoma|Rectal Adenocarcinoma|Stage III Rectal Cancer AJCC v7|Stage IIIA Rectal Cancer AJCC v7|Stage IIIB Rectal Cancer AJCC v7|Stage IIIC Rectal Cancer AJCC v7|Stage IV Rectal Cancer AJCC v7|Stage IVA Rectal Cancer AJCC v7|Stage IVB Rectal Cancer AJCC v7
Interventions: DRUG: Capecitabine|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|RADIATION: Radiation Therapy|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of the Safety, Reactogenicity and Immunogenicity of the GamFluVac
Status: COMPLETED
Conditions: Influenza A Virus Infection|Influenza A|Influenza Epidemic|Influenza H5N1
Interventions: BIOLOGICAL: GamFluVac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Formula Fortified With DHA in Infants With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid (DHA)|DIETARY_SUPPLEMENT: Standard formula (Enfamil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of Asoprisnil(J867) in Women With Uterine Fibroids Who Are Scheduled for a Hysterectomy
Status: COMPLETED
Conditions: Uterine Fibroids|Leiomyoma
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry)
Status: RECRUITING
Conditions: Lower Limb Ischemia|Peripheral Arterial Disease|Chronic Limb-Threatening Ischemia|Chronic Limb Ischemia|Atherosclerosis of Femoral Artery|Superficial Femoral Artery Stenosis|Superficial Femoral Artery Occlusion|Superficial Femoral Artery Disease|Superficial Femoral Artery Lesions|Popliteal Artery Occlusion|Popliteal Artery Stenosis|Popliteal Arterial Stenosis
Interventions: DEVICE: Supera Vasculomimetic Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onset Time of Brachial Plexus Block Using Local Anaesthetic Diluted With 0.9% Saline vs 5% Dextrose
Status: COMPLETED
Conditions: Comparison of Onset Time
Interventions: DRUG: 0.75% Ropivacaine|DRUG: Normal saline|DRUG: Dextrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Efficacy and Safety of Nivolumab (Optivo®) in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort.
Status: UNKNOWN
Conditions: COVID19- Infection With SARS-CoV-2 Virus
Interventions: DRUG: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor: A Proof of Principle Trial
Status: COMPLETED
Conditions: Atypical Ductal Breast Hyperplasia|Lobular Carcinoma in Situ (LCIS)|Atypical Lobular Hyperplasia (ALH) of Breast
Interventions: DRUG: SOM 230 / Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma
Interventions: GENETIC: Autologous HER2-specific T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide|GENETIC: Autologous CAR Positive T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oblimersen, Rituximab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: BIOLOGICAL: oblimersen sodium|BIOLOGICAL: rituximab|DRUG: ifosfamide|DRUG: carboplatin|DRUG: etoposide|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Serial Ultrasound Screening in ICU COVID-19 Patients
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Covid19|COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Acute Bronchitis|COVID-19 Lower Respiratory Infection|Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: venous ultrasound of lower extremity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Utilisation of Telemedicine in Optimal Cardiac Rehabilitation Program in Patients After Myocardial Revascularization
Status: UNKNOWN
Conditions: Coronary Artery Disease With Myocardial Infarction
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Anlotinib in Patients With Advanced Renal Cell Carcinoma That Have Failed Or Are Intolerant To TKIs Therapy
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Work Outcome for People With Severe Mental Illness
Status: COMPLETED
Conditions: Schizophrenia, Schizotypal and Delusional Disorders|Bipolar Affective Disorder|Recurrent Depressive Disorder
Interventions: BEHAVIORAL: Individual Placement and support (IPS)|BEHAVIORAL: IPS plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: EXpression PRofile Endometrium Samples Study
Status: TERMINATED
Conditions: In Vitro Fertilization
Interventions: DRUG: Gonal -f® [r-hFSH]|DRUG: Ovitrelle® [r-hCG alfa]|DRUG: Gonadotropin-releasing hormone (GnRH) Agonist|DRUG: Gonadotropin-releasing hormone (GnRH) Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Foot Bath and Lavender Oil Sniffing on the Severity of Insomnia in Cancer Patients
Status: UNKNOWN
Conditions: Cancer Patient
Interventions: OTHER: To evaluate the effect of foot bath applied for 2 weeks on insomnia in cancer patients.|OTHER: To evaluate the effectiveness of smelling lavender oil applied to cancer patients for 2 weeks on sleep.|OTHER: To evaluate the effect of foot bath and lavender oil applied for 2 weeks on insomnia in cancer patients.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy and Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Combination of Prednisone and Recombinant Human Thrombopoietin for Treatment of Immune Thrombocytopenia in Pregnancy
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Prednisone|DRUG: Recombinant Human TPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of CTC´s Spread During Pancreaticoduodenectomy in Patients With Pancreatic and Periampullary Tumors
Status: COMPLETED
Conditions: Pancreatic Tumor|Periampullary Carcinoma Resectable|Circulating Tumor Cells|Metastasis
Interventions: PROCEDURE: No Touch (NT)|PROCEDURE: Superior Mesenteric Artery First (SMA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in China
Status: COMPLETED
Conditions: Opiate Dependence|HIV Infections
Interventions: BEHAVIORAL: Behavioral Drug and HIV Risk Reduction Counseling (BDRC)|BEHAVIORAL: Drug counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Toddlers (12-18 Months) Comparing a Booster Dose of Vaxem Hib and Hiberix Vaccines for the Prevention of Haemophilus Influenzae Type b Infections in China
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b (Hib) Infection
Interventions: BIOLOGICAL: Vaxem Hib (Haemophilus influenzae type b (Hib) vaccine)|BIOLOGICAL: Hiberix (Haemophilus influenzae type b (Hib) vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treprostinil Combined With Tadalafil for Pulmonary Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Dry Socket by Means of Single Preoperative Antibiotics Compared to Conventional Therapy
Status: COMPLETED
Conditions: Dry Socket
Interventions: DRUG: Amoxicillin 500 Mg|DRUG: metronidazole 400mg|DRUG: metronidazol 400mg and amoxicillin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Carcinoma of Unknown Primary|Endometrial Carcinoma|Esophageal Carcinoma|Liver Failure|Lung Carcinoma|Malignant Head and Neck Neoplasm|Malignant Testicular Neoplasm|Melanoma|Metastatic Malignant Solid Neoplasm|Ovarian Carcinoma|Renal Failure|Unresectable Malignant Neoplasm|Urothelial Carcinoma
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aprepitant Versus Gabapentin in the Prevention of Delayed Nausea and Vomiting
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Aprepitant vs. Gabapentin|DRUG: Aprepitant vs. Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Treatment Outcomes for Prescription Opioid Dependence
Status: COMPLETED
Conditions: Drug Dependence
Interventions: DRUG: Gabapentin|DRUG: Buprenorphine|DRUG: Clonidine|DRUG: Naltrexone (oral)|DRUG: Naltrexone (depot)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Cannabigerol
Status: COMPLETED
Conditions: Focus: To Examine Acute Effects of CBG on Anxiety, Stress, and Cognition
Interventions: DRUG: Cannabigerol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Endoscopy Bipolar and Argon of Chronic Rectal Bleeding From Radiation Telangiectasias
Status: COMPLETED
Conditions: Radiation Injuries|Telangiectasis
Interventions: DEVICE: Bipolar eletrocoagulation|DEVICE: Argon Plasma Coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Inflammatory Bowel Disease Mediterranean Diet (IBDMED) Microbiome-targeting Nutritional Education Program
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: IBDMED|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors
Status: SUSPENDED
Conditions: Brain Cancer|Malignant Brain Tumor|Recurrent Brain Tumor|Progressive Malignant Brain Tumor|Brain Tumor, Pediatric|Brain Tumor Adult
Interventions: DRUG: Magrolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Trail of Camrelizumab Plus Apatinib Mesylate for Advanced Gastrointestinal
Status: UNKNOWN
Conditions: Gastrointestinal Cancer|Immunotherapy|Targeted Therapy
Interventions: DRUG: Camrelizumab|DRUG: Apatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Hyaluronic Acid Injection Following Knee Arthroscopy
Status: UNKNOWN
Conditions: Cartilage Damage
Interventions: DRUG: Sodium Hyaluronate 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Pharmacokinetics of Dipyridamole in Three New Formulations of Asasantin ER in Healthy Female and Male Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Asasantin ER (new formulation - low)|DRUG: Asasantin ER (new formulation - medium)|DRUG: Asasantin ER (new formulation - high)|DRUG: Asasantin ER - commercial formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: PROCEDURE: Pulsatile Intravenous Insulin Therapy (Humulin, Humulog, Novolog )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Sacituzumab Govitecan Alone in the Treatment of Advanced Urothelial Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Urothelial Carcinoma|Metastatic Urothelial Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration|BIOLOGICAL: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota Profiling in Severe Acute Alcoholic Hepatitis Patients
Status: RECRUITING
Conditions: Severe Acute Alcoholic Hepatitis|Alcohol|Intestinal Microbiota|Corticosteroids
Interventions: OTHER: stool withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pegfilgrastim and Rituximab in Treating Patients With Untreated, Relapsed, or Refractory Follicular Lymphoma, Small Lymphocytic Lymphoma, or Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Contiguous Stage II Grade 1 Follicular Lymphoma|Contiguous Stage II Grade 2 Follicular Lymphoma|Contiguous Stage II Grade 3 Follicular Lymphoma|Contiguous Stage II Marginal Zone Lymphoma|Contiguous Stage II Small Lymphocytic Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Noncontiguous Stage II Grade 1 Follicular Lymphoma|Noncontiguous Stage II Grade 2 Follicular Lymphoma|Noncontiguous Stage II Grade 3 Follicular Lymphoma|Noncontiguous Stage II Marginal Zone Lymphoma|Noncontiguous Stage II Small Lymphocytic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Stage I Grade 1 Follicular Lymphoma|Stage I Grade 2 Follicular Lymphoma|Stage I Grade 3 Follicular Lymphoma|Stage I Marginal Zone Lymphoma|Stage I Small Lymphocytic Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Small Lymphocytic Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|OTHER: flow cytometry|PROCEDURE: biopsy|OTHER: immunohistochemistry staining method|GENETIC: western blotting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Surgery With Early vs Delayed Endodontic Treatment in Endo-Perio Lesions Without Communication
Status: UNKNOWN
Conditions: Periodontal and Endodontic Lesion
Interventions: PROCEDURE: open flap debridement|PROCEDURE: open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Treatments in Reducing Dissociative Seizure Occurrence
Status: COMPLETED
Conditions: Convulsion, Nonepileptic|Conversion Disorder|Dissociative Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Standardized Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors
Status: TERMINATED
Conditions: Non-Malignant Hematologic Disorders
Interventions: DRUG: Melphalan|DRUG: Thiotepa|DRUG: Clofarabine|DRUG: Fludarabine|DRUG: Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®)|PROCEDURE: CliniMACS reagents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of BI 2536 Administered in Combination With Gemcitabine in Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: BI 2536, intravenous|DRUG: Gemcitabine, intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin
Status: COMPLETED
Conditions: Respiratory Tract Infections|Fever
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)|DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)|DRUG: Paracetamol|DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Metabolism and Oxygenation During Localized Fatigue-exercise in COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Fatiguing exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Ambroxol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment
Status: TERMINATED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: Selexipag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Subcutaneous Insulin Glargine Plus Standard of Care for Treatment of Diabetic Ketoacidosis
Status: COMPLETED
Conditions: Diabetic Ketoacidosis
Interventions: OTHER: Early administration of subcutaneous insulin glargine dose|OTHER: IV insulin infusion|DRUG: IV fluid repletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Effectiveness of Mirror-Box and Mental Visualization Treatments on Phantom Limb Pain
Status: UNKNOWN
Conditions: Amputation|Phantom Limb|Pain
Interventions: DEVICE: mirror-box treatment|BEHAVIORAL: Mental visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextroamphetamine and tDCS to Improve the Fluency
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Dexedrine|DEVICE: Active tDCS|BEHAVIORAL: Speech Therapy|DRUG: Placebo|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Veterans With Military Sexual Trauma
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depressive Symptoms|Anxiety Symptoms|Quality of Life
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Present-Centered Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Saphenous Nerve Block Versus Platelet Rich Plasma for Chronic Knee Osteoarthritis
Status: COMPLETED
Conditions: Chronic Knee Joint Osteoarthritis
Interventions: OTHER: Saphenous nerve block group|OTHER: Platelet rich plasma group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot
Interventions: DEVICE: Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability,and Efficacy of VCN-01 With Durvalumab in R/M Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Neoplasms|Carcinoma, Squamous Cell of Head and Neck|Metastasis|Recurrence
Interventions: GENETIC: VCN-01|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment With Preservative-free Dexamethasone 0.1% (Monofree Dexamethason) and Diclofenac 0.1% (Dicloabak) Eye Drops Versus Preserved Dexamethasone 0.1% (Maxidex) and Diclofenac 0.1% (Voltaren Ophtha) Eye Drops After Cataract Surgery
Status: RECRUITING
Conditions: Age-related Cataract
Interventions: DRUG: Preservative Free drop treatment|DRUG: Preserved drop treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Baloxavir Marboxil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Control Scan for Presumed Difficult Epidural Infiltrations (ECHORACHIS)
Status: COMPLETED
Conditions: Sciatica
Interventions: PROCEDURE: Group " with scan prior to infiltration "|PROCEDURE: Group " without scan "
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Trial to Evaluate the Safety of Once Weekly Dosing of Somapacitan (NNC0195-0092) and Daily Norditropin® FlexPro® for 52 Weeks in Previously Human Growth Hormone Treated Japanese Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency
Interventions: DRUG: somapacitan|DRUG: Norditropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Nanosomal Docetaxel Lipid Suspension in Triple Negative Breast Cancer Patients
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Nanosomal Docetaxel Lipid Suspension (75 mg/m2)|DRUG: Nanosomal Docetaxel Lipid Suspension (100 mg/m2)|DRUG: Taxotere® (100 mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls
Status: UNKNOWN
Conditions: Anaemia
Interventions: DRUG: Iron, Folic acid and Cyanocobalamin|DRUG: Iron and Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vincristine, Escalating Doses of Irinotecan, Temozolomide and Bevacizumab (Vit-b) in Pediatric and Adolescent Patients With Recurrent or Refractory Solid Tumors of Non-hematopoietic Origin
Status: COMPLETED
Conditions: Refractory Solid Tumors in Children
Interventions: DRUG: Irinotecan|DRUG: Vincristine|DRUG: Temozolomide|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acclarent Tympanostomy Tube Delivery System for the Treatment of Patients Requiring Tympanostomy Tube Insertion
Status: COMPLETED
Conditions: Otitis Media
Interventions: DEVICE: Acclarent Tympanostomy Tube Delivery System (TTDS).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Language Development|Literacy
Interventions: BEHAVIORAL: Structural vs. Random sequences of stimuli|BEHAVIORAL: Intact vs. Degraded speech|BEHAVIORAL: Repeating 5-syllable nonwords or 2-syllable nonwords|BEHAVIORAL: Recall letter or syllable strings that either contain highly frequent bigram/trigram items or infrequent items according to English Corpus data.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Trial of Continuous Infusion UCN-01 in Patients With Refractory Neoplasms
Status: COMPLETED
Conditions: Breast Cancer|Lymphoma|Neoplasm|Prostatic Neoplasm
Interventions: DRUG: 7-hydroxystaurosporine (UCN-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall
Status: TERMINATED
Conditions: Recurrent Adult Soft Tissue Sarcoma|Stage I Adult Soft Tissue Sarcoma AJCC v7|Stage II Adult Soft Tissue Sarcoma AJCC v7|Stage III Adult Soft Tissue Sarcoma AJCC v7
Interventions: DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Filgrastim|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy|DRUG: Thalidomide|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique and Hamstring Nordic Lower for Hamstring Tightness in Young Athletes
Status: COMPLETED
Conditions: Hamstring Tightness|Athletic Injuries|Athletic Performance
Interventions: OTHER: post facilitation stretch|OTHER: post isometric relaxation|OTHER: hamstring nordic lower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Glucagon-like Peptide-1 Levels and In-hospital Complications in ST-segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction|Glucagon-like Peptide-1|Bleeding|Complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Phase IVc of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell)
Status: UNKNOWN
Conditions: Hand, Foot and Mouth Disease (HFMD)
Interventions: BIOLOGICAL: Inactivated EV71 vaccine (human diploid cell, KMB-17)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bipolar Sealer Aquamantys Use in Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis|Arthritis|Surgery|Infection|Inflammation|Disability|Hemorrhage
Interventions: DEVICE: Electrocautery|DEVICE: Bipolar sealer Aquamantys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Determine the Bioequivalence of Two Formulations of Tamsulosin HCl Capsules in Fed Male.
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: tamsulosin (Astellas)|DRUG: Tamsulosin HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy aNd Safety of Jinlida Granules in Patients With Inadequately cOntrolled tYpe-2 Diabetes and dysLIpidemia Under liFe Style Intervention (ENJOY LIFE Study)
Status: UNKNOWN
Conditions: Type 2 Diabetes|Dyslipidemia
Interventions: DRUG: Jinlida granules|DRUG: placebo granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
Status: COMPLETED
Conditions: Pathological Myopia
Interventions: DRUG: Ranibizumab|DRUG: Verteporfin PDT|DRUG: Sham Ranibizumab|DRUG: Sham verteporfin PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PD-1/PD-L1 Inhibitors and Anti-angiogenic Therapy Combined With/Without TACE/HAIC in Patients With BCLC B/C Hepatocellular Carcinoma Beyond Up-to-7
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE/HAIC|DRUG: PD-1/PD-L1 inhibits and anti-angiogenic agents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Bronchiolitis|Lower Respiratory Tract Infection|Bronchial Hyperreactivity
Interventions: OTHER: Oxygen saturation threshold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marine Protein Hydrolysate as Dietary Supplement in Elderly Part II
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: marine protein hydrolysate 1234|DIETARY_SUPPLEMENT: marine protein hydrolysate 2134|DIETARY_SUPPLEMENT: marine protein hydrolysate 3124|DIETARY_SUPPLEMENT: marine protein hydrolysate 4123
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Prednisolone and Dexamethasone
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Prednisolone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safeyt Profile of Test Product Compared to Reference Product Will be Assessed.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Vildagliptin 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety of Dengue Tetravalent Vaccine (TDV) and Recombinant 9-valent Human Papillomavirus Vaccine (9vHPV) in Participants Aged ≥9 to <15 Years
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: 9vHPV Vaccine|BIOLOGICAL: Dengue Tetravalent Vaccine (TDV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery
Status: WITHDRAWN
Conditions: Tranexamic Acid|Orthognathic Surgery
Interventions: DRUG: Tranexamic Acid Injectable Solution|OTHER: Placebo (normal saline 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: a. Reducing Radioiodine Treatment in Papillary Thyroid Cancer. RAILESS
Status: ACTIVE_NOT_RECRUITING
Conditions: to Omit Radioiodine Treatment Safely in Patients With Low -Risk Papillary Thyroid Cancer With Seize of 11-20mm
Interventions: OTHER: With radioiodine treatment|PROCEDURE: With postoperative radioiodine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of dermaPACE™ Device and Standard Treatment Compared to Standard Treatment Alone for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: acoustical pulse energy (extracorporeal shockwave)|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment on Efficacy and Safety of BAT2306 and Cosentyx® in Plaque Psoriasis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: BAT2306|DRUG: EU-approved Cosentyx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Percussive Massage Treatment With Theragun on Post Exercise Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: OTHER: Percussive massage and static stretching exercises|OTHER: static stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irbesartan/Amlodipine in Hypertensive Patients Uncontrolled on Amlodipine 5 mg Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: irbesartan/amlodipine|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Etomidate on Adrenal Function in Trauma Patients
Status: COMPLETED
Conditions: Adrenal Insufficiency
Interventions: DRUG: RSI sedation with etomidate/succinylcholine|DRUG: RSI sedation with fentanyl/midazolam/succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Thread Embedding Acupuncture for Pain and Quality of Life in Endometriosis Patients
Status: RECRUITING
Conditions: Endometriosis-related Pain
Interventions: PROCEDURE: Thread embedding acupuncture (TEA) + standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment
Status: COMPLETED
Conditions: Cryotherapy Effect|Warts
Interventions: DEVICE: EndWarts® FREEZE|DEVICE: Liquid nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seizure Therapy With Intravenous Levetiracetam and Lorazepam
Status: WITHDRAWN
Conditions: Seizures
Interventions: DRUG: Levetiracetam 1 g IV + Lorazepam 2 mg IV|DRUG: Placebo + Lorazepam 3 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatments for Anxiety: Meditation and Escitalopram
Status: COMPLETED
Conditions: Anxiety Disorders|Generalized Anxiety Disorder|Panic Disorder|Social Anxiety Disorder|Agoraphobia
Interventions: OTHER: Mindfulness-Based Stress Reduction|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aralast alpha1-proteinase Inhibitor Surveillance Study
Status: TERMINATED
Conditions: Alpha1-antitrypsin Deficiency
Interventions: DRUG: ARALAST Alpha1-Proteinase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: MK-1092, 4.0 nmol/kg|DRUG: MK-1092, 8.0 nmol/kg|DRUG: MK-1092, 16 nmol/kg|DRUG: MK-1092, 32 nmol/kg|DRUG: MK-1092, 64 nmol/kg|DRUG: Glargine 3.0 nmol/kg|DRUG: Lispro 1.2 nmol/kg|DRUG: Placebo to glargine|DRUG: Placebo to MK-1092|OTHER: Dextrose|BIOLOGICAL: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Administration of Heparin as Thromboprophylaxis in Major Thoracic Surgery
Status: UNKNOWN
Conditions: Thromboprophylaxis|Thoracic Surgery
Interventions: DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: This Study Tests Whether BI 409306 Prevents Patients With Schizophrenia From Becoming Worse. This Study Looks at How Well Patients Tolerate BI 409306 and How Effective it is Over 6 Months
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: BI 409306|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children
Status: COMPLETED
Conditions: Tonsillitis
Interventions: DRUG: pristinamycin|DRUG: amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Real World Tumor Response in Pre-menopausal Metastatic Breast Cancer Patients Treated With Palbociclib + Aromatase Inhibitor or Aromatase Inhibitor Alone
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib + aromatase inhibitor|DRUG: Aromatase inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Metformin|Obesity, Abdominal|Diabetes Mellitus, Type 2|Abdominal Fat|Non-Alcoholic Fatty Liver Disease|Metabolism Disorder, Glucose|Metabolism Disorder, Lipid
Interventions: DRUG: Liraglutide|DRUG: Semaglutide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semaglutide vs Sitagliptin
Status: ENROLLING_BY_INVITATION
Conditions: Liver Transplant; Complications|Diabetes Mellitus|NASH - Nonalcoholic Steatohepatitis|NAFLD
Interventions: DRUG: Semaglutide Treatment|DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Ultrasound (EBUS) for Nodal Staging in Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Endoscopic Ultrasound (EUS)|PROCEDURE: Endobronchial Ultrasound (EBUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analyzing the Impact of the Now iKnow Health Care Price Transparency Tool
Status: COMPLETED
Conditions: no Specific Condition Targeted|Use of a Price Transparency Tool
Interventions: OTHER: lottery for tool users to win a $500 prize|OTHER: enhanced promotion of the tool to employers and members
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perforating Cutaneous Nerve Injection Efficacy in Chronic Coccydynia: A Randomized, Double-Blind Study
Status: RECRUITING
Conditions: Coccyx Disorder|Coccyx Injury
Interventions: PROCEDURE: US Guided Perineural Injection and Neuroprolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Passive Leg Raising for Fluid Responsiveness
Status: UNKNOWN
Conditions: Body Fluid Retention|Impedance|Cardiac Output, Low
Interventions: DEVICE: CardioScreen 1000 - Haemodynamic Measurement System, Medis|DEVICE: SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Milk Fat Globule Membrane Supplementation on Heart and Brain Health
Status: RECRUITING
Conditions: Cardiovascular Diseases|Overweight and Obesity|Cognition
Interventions: DIETARY_SUPPLEMENT: Experimental: Milk Fat Globule Membrane-enriched Powdered Ingredient|DIETARY_SUPPLEMENT: Placebo Comparator: Control (Placebo) Powdered Ingredient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective and Randomized Study to Evaluate Interest of Ultracision Use in Inguinal Lymph Nodes Curage
Status: COMPLETED
Conditions: Vulvar Neoplasms|Skin Neoplasms
Interventions: DEVICE: ultracision|DEVICE: classical lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Use of Vaginal Balls for the Improvement of Urinary Incontinence and Sexual Function in Women.
Status: COMPLETED
Conditions: Urinary Incontinence|Stress Urinary Incontinence|Sexual Dysfunction
Interventions: DEVICE: Intervention group with Enna pelvic ball|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension.
Status: COMPLETED
Conditions: Idiopathic Intracranial Hypertension
Interventions: DRUG: AZD4017|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New MRT Imaging Biomarkers and Treatment With Kinetic Oscillatory Stimulation (KOS) in Nasal Cavity for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Status: UNKNOWN
Conditions: Myalgic Encephalomyelitis|Chronic Fatigue Syndrome
Interventions: DEVICE: Inactive Kinetic Oscillation Stimulation (KOS)|DEVICE: Active Kinetic Oscillation Stimulation (KOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT