pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: iNO|PROCEDURE: Non-invasive nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Peginterferon Alfa-2b Monotherapy and Combination With Ribavirin in Participants With Acute Hepatitis C (P03552/MK-4031-137)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Pegylated interferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belatacept in Kidney Transplantation of Moderately Sensitized Patients
Status: WITHDRAWN
Conditions: End Stage Renal Disease|Antibody Mediated Rejection
Interventions: DRUG: Belatacept|DRUG: Tacrolimus withdrawal|PROCEDURE: Plasmapheresis/Intravenous Immunoglobulin G|DRUG: Thymoglobulin (ATG)|DRUG: Myfortic|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-dose Maintenance Peg Interferon Alfa-2b Therapy Versus Supportive Care in Patients With Cirrhotic Hepatitis C With HIV (Study P04371)
Status: WITHDRAWN
Conditions: Hepatitis C|Liver Cirrhosis|HIV Infections
Interventions: DRUG: Peg interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Arginine as a Treatment for Sickle Cell Anemia
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: Arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET-MRI in Diagnosing Patients With Colon or Rectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IIA Colon Cancer|Stage IIA Rectal Cancer|Stage IIB Colon Cancer|Stage IIB Rectal Cancer|Stage IIC Colon Cancer|Stage IIC Rectal Cancer|Stage IIIA Colon Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The ED50 of DEX for Providing Sedation in Different Female Age Group
Status: UNKNOWN
Conditions: Combined Spinal-epidural Anesthesia
Interventions: DRUG: Dexmedetomidine A|DRUG: Dexmedetomidine B|DRUG: Dexmedetomidine C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxytyrosol Caramel Treatment on Cardiovascular Risk Patients
Status: COMPLETED
Conditions: Cardiovascular Pathology
Interventions: DIETARY_SUPPLEMENT: HT treatment|DIETARY_SUPPLEMENT: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Intra-Cardiac Echocardiography in Guiding Left Atrial Appendage Occlusion With the Watchman Device
Status: COMPLETED
Conditions: Left Atrial Appendage Occlusion
Interventions: DEVICE: intra-procedural intracardiac echocardiography (ICE) probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of BodPod in Pediatric Anorexia Nervosa
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: OTHER: Measure of body composition by Air Displacement Plethysmography (ADP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endostar Combined With Paclitaxel and Nedaplatin in Treating Patients With Recurrent or Metastatic Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel+Nedaplatin+Endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bavituximab Plus Paclitaxel and Carboplatin in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: bavituximab plus paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Assessment of Huafu Shengji Ointment in Patients With Diabetic Foot of Qi Deficiency and Blood Stasis Syndrome
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot
Interventions: DRUG: Huafu Shengji Ointment|DRUG: ethacridine lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol/Acetaminophen(Ultracet) AS add-on Therapy in the Treatment of Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Ultracet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Breathing Exercise and Affirmation Method Used in Labor on Women's Birth Self-Efficacy and Satisfaction
Status: COMPLETED
Conditions: Birth Self-efficacy|Birth Satisfaction
Interventions: BEHAVIORAL: Breathing Exercise|BEHAVIORAL: Affirmation Method|BEHAVIORAL: Breathing Exercise and Affirmation Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Roxadustat for the Treatment of Anemia in Participants Receiving Chemotherapy Treatment for Non-Myeloid Malignancies
Status: COMPLETED
Conditions: Chemotherapy Induced Anemia
Interventions: DRUG: SEPO®|DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline for the Treatment of Smokeless Tobacco
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antenatal Corticosteroids on the Fetal Thymus - a Possible Role in Fetal Immune Programming
Status: COMPLETED
Conditions: Preterm Labor|Fetal Glucocorticoid Exposure
Interventions: OTHER: 2D ultrasound assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and Immunogenicity of Autologous Thrombosomes® in Healthy Human Subjects; A Microdose Escalation Study (Cohorts 1 - 4) and Repeat Microdose Immunogenicity Study (Cohort 5)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Thrombosomes|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Depression Identification After Acute Coronary Syndrome: Quality of Life and Cost Outcomes
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Depressive Symptoms
Interventions: OTHER: Cognitive Behavioral Therapy (CBT)|DRUG: Antidepressant Medication|OTHER: Standard Care|OTHER: Depressive symptom screener|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
Status: COMPLETED
Conditions: Depression, Postpartum|Depression
Interventions: BEHAVIORAL: Behavioral education intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Potassium, Hydration, Cardiovascular, and Kidney Study
Status: NOT_YET_RECRUITING
Conditions: Blood Pressure|Hydration
Interventions: DIETARY_SUPPLEMENT: Water and Potassium supplementation|OTHER: Water alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus|Obesity|Nephropathy|Adolescent Obesity
Interventions: DRUG: Aminohippurate Sodium Inj 20%|DRUG: Iohexol Inj 300 MG/ML|PROCEDURE: Renal Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Observe How Well That BAT8006 Works on Patients With Platinum Resistance Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Platinum-resistant Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: BAT8006 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With Cancer
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Malnutrition|Myelodysplastic Syndromes|Unspecified Childhood Solid Tumor, Protocol Specific|Weight Changes
Interventions: DIETARY_SUPPLEMENT: Ensure|DIETARY_SUPPLEMENT: PediaSure|DRUG: cyproheptadine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacodynamic and Safety of MEDITOXIN® in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Meditoxin|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ability of a New Design of Iodine 125 Seed to Maintain Intended Position When Implanted in the Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Iodine 125 standard loose brachytherapy seeds|RADIATION: AnchorSeed Iodine 125 brachytherapy prostate implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Status: RECRUITING
Conditions: Hemolytic Disease of the Fetus and Newborn
Interventions: DRUG: Nipocalimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategies for IgG4-RD Patients With Internal Organ Involvement
Status: RECRUITING
Conditions: Autoimmune Diseases
Interventions: DRUG: Prednisone and Mycophenolate Mofetil|DRUG: Mycophenolate Mofetil|DRUG: Leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Training on Salivary Immunoglobulin A in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma
Status: WITHDRAWN
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Latanoprost-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences for Sugar-Sweetened Beverages
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes|Dental Caries
Interventions: BEHAVIORAL: Sugar-Sweetened Beverage (SSB) Video|BEHAVIORAL: Water Video|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Peribulbar Rocuronium in Adult Strabismus Surgery
Status: RECRUITING
Conditions: Strabismus|Regional Anesthesia Morbidity|Rocuronium
Interventions: DRUG: Normal saline|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Finding Study to Evaluate The Safety, Tolerability and Immunogenicity of an Inactiviated, Adjuvanted SARS-CoV-2 Virus Vaccine Candidate Against Covid-19 in Healthy Subjects
Status: COMPLETED
Conditions: SARS-CoV-2 Virus Infection
Interventions: BIOLOGICAL: VLA2001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of GCS-100LE in the Treatment of Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: GCS-100|DRUG: Bortezomib/Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium90, Ipilimumab, & Nivolumab for Uveal Melanoma With Liver Metastases
Status: UNKNOWN
Conditions: Uveal Melanoma|Hepatic Metastases
Interventions: DEVICE: SIR-Spheres® Yttrium 90|DRUG: ipilimumab|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase ll Study of IMM-124E for Patients With Non-alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: BIOLOGICAL: IMM-124E|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Soy-based Meal Replacement Weight Loss Intervention to Impact Ectopic Fat
Status: COMPLETED
Conditions: Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: Medifast meal replacement products|DIETARY_SUPPLEMENT: Medifast meal replacement products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Cervical Cancer|Endometrial Cancer|Non Small Cell Lung Cancer (NSCLC)|Thyroid Cancer|Melanoma|Sarcoma|Solid Tumors
Interventions: BIOLOGICAL: Enapotamab vedotin (HuMax-AXL-ADC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI
Status: UNKNOWN
Conditions: Acneiform Eruptions|Cancer, Treatment-Related
Interventions: DRUG: Doxycycline 100mg po once daily x 6 months|DRUG: Isotretinoin 40 mg po once daily x 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8008 for Injection
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BAT8008 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Cardiovascular Suboptimal Health
Status: COMPLETED
Conditions: Suboptimal Health Status
Interventions: DIETARY_SUPPLEMENT: Omega -3 fatty acids|DIETARY_SUPPLEMENT: Placebo: Corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Arteriopathy and Endothelial Function
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Fruit juice or placebo absorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Technology-Based System for Patient Engagement and Physician-Directed Remote Management of Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: A combination of a provider-facing desktop and mobile application with a patient-facing mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacological Modulation of Brain Oscillations in Memory Processing
Status: RECRUITING
Conditions: Epilepsy|Seizures|Cognitive Impairment, Mild|Memory Disorders|Memory Loss
Interventions: DRUG: Scopolamine (5ug/kg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Elastography and Thermography Plantar Fasciopathy Assessment After Radiofrequency Stimulation in a Sporty Population
Status: UNKNOWN
Conditions: Plantar Fascia; Contracture
Interventions: DEVICE: Radiofrecuency
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection
Status: TERMINATED
Conditions: COVID-19|SARS-CoV 2
Interventions: DRUG: Hydroxychloroquine|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Status: RECRUITING
Conditions: Antiphospholipid Syndrome (APS)|Bullous Pemphigoid (BP)|Behçet's Syndrome (BS)|Dermatomyositis (DM)|Immune-mediated Necrotizing Myopathy (IMNM)|Immune Thrombocytopenia (ITP)
Interventions: DRUG: RAY121
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Based Family Therapy for Improving Treatment Outcome for People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Culturally informed therapy for schizophrenia (CIT-S)|BEHAVIORAL: Psychoeducation treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AVE8062 in Advanced-stage Soft Tissue Sarcoma After Failure of Anthracycline and Ifosfamide Chemotherapies
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: OMBRABULIN (AVE8062)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Clindamycin Cream Plus Vaginal Probiotic for Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginosis Treatment
Interventions: DRUG: Vaginal Clindamycin Cream|DRUG: Vaginal Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Micronized Purified Flavonoid- Fraction (MPFF) in the Management of Radiation Proctitis
Status: UNKNOWN
Conditions: Proctitis Radiation
Interventions: DRUG: MMPF (Micronized purified Flavonoid-Fraction)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Supplementation With Linseed Oil on Blood Lipids in Vegetarians
Status: COMPLETED
Conditions: Inter-conversion n-3 PUFA, Vegetarians
Interventions: DIETARY_SUPPLEMENT: Linseed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Immunogenicity and Safety of PENTAXIM™ in Philippines
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Polio|Pertussis|Haemophilus Influenzae Type B
Interventions: BIOLOGICAL: Diphteria, Tetanus, Polio, Acellular Pertussis, Hib vaccine|BIOLOGICAL: Diphteria, Tetanus, Polio, Acellular Pertussis, Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Merit WRAPSODY™ Endovascular Stent Graft
Status: COMPLETED
Conditions: Venous Stenosis|Venous Occlusion
Interventions: DEVICE: WRAPSODY Stent Graft Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Organic Germanium or Placebo for the Prevention of Radiation Induced Fatigue
Status: UNKNOWN
Conditions: Localized Breast Cancer|Localized Prostate Cancer|Patients Receiving External Beam Radiotherapy
Interventions: DIETARY_SUPPLEMENT: Organic Germanium|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT of Screening Strategies Among Patients at High Risk for Developing HCC in a Safety-net Health System
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Liver Neoplasms
Interventions: OTHER: Mailed Outreach Invitation|OTHER: Mailed Outreach Invitation and Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Machine-based Algorithm for Increased Physical Activity and Sustained User Engagement
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Behavior
Interventions: BEHAVIORAL: Adaptive Step Goal (Intervention)|BEHAVIORAL: Static Step Goal (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chanjo Kwa Wakati - Improving Vaccination Coverage and Timeliness in Rural Settings
Status: RECRUITING
Conditions: Vaccination|Short Message Service (SMS)|Incentives|Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Chanjo Kwa Wakati - Knowledge Intervention|BEHAVIORAL: Chanjo Kwa Wakati - Reminders|BEHAVIORAL: Chanjo Kwa Wakati - Incentives|BEHAVIORAL: Chanjo Kwa Wakati - Service notifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Influenza Vaccination on IVF Outcomes - IVF
Status: ENROLLING_BY_INVITATION
Conditions: Infertility
Interventions: BIOLOGICAL: Influenza Vaccine|OTHER: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-proliferative Diabetic Retinopathy
Interventions: DRUG: OTX-TKI|DRUG: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Ruxolitinib Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Single-arm, Open, Phase I/IIa Clinical Trial to Evaluate the Efficacy and Safety of EBViNT Cell (EBV Specific Autologous CD8+ T Cell) in Patients With Treatment Failed Epstein Barr Virus (EBV)-Positive Malignancies
Status: RECRUITING
Conditions: EBV Associated Extranodal NK/T-cell Lymphoma|EBV-Associated GastricCarcinoma or Esophageal AdenoCarcinoma
Interventions: BIOLOGICAL: EBViNT Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Treatment of Recalcitrant Ulcerative Old World Leishmaniasis With WR 279,396
Status: TERMINATED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Paromomycin +Gentamicin topical cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients
Status: RECRUITING
Conditions: Critical Illness|New Onset Atrial Fibrillation
Interventions: DRUG: Magnesium sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Dipotassium Glycyrrhizinate Emollients in the Maintenance Treatment of Adult Atopic Dermatitis
Status: COMPLETED
Conditions: Adult Atopic Dermatitis
Interventions: DRUG: White yu green skin lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety Study of a Meningococcal Serogroup B Vaccine Given in a 3 Dose Schedule to Healthy Adolescents Aged 12-18 Yrs
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal serogroup B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Assessment Of Association Pharmacokinetics Atorvastatin + Losartana + Hydrochlorothiazide
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Atorvastatin|DRUG: Hydrochlorothiazide + Losartan|DRUG: Hydrochlorothiazide + Losartan + Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POWER: PrehabilitatiOn Workshop and Mentored Exercise Programme in Patients Having Elective Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Vascular Surgery
Interventions: BEHAVIORAL: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Graft-vs-Host Disease
Interventions: DRUG: Sirolimus|DRUG: Mycophenolate mofetil|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single-dose Prophylactic INdomethacin in Extremely Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Extreme Prematurity|Intraventricular Hemorrhage|Morbidity;Newborn
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive AppRoaches to coMbatting Suicidality
Status: COMPLETED
Conditions: Psychosis|Suicide Prevention|Suicidality
Interventions: OTHER: Cognitive AppRoaches to coMbatting Suicidality (CARMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study to Evaluate the Tolerability of Oph1 Compared to Restasis in Healthy Volunteers
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Oph1|DRUG: Restasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Observational Study of Incidence Rates of Esophageal Cancer in Women Taking Medications for the Prevention or Treatment of Osteoporosis (MK-0217A-352)
Status: COMPLETED
Conditions: Esophageal Cancer|Squamous Cell Carcinoma|Adenocarcinoma
Interventions: DRUG: Alendronate|DRUG: Etidronate|DRUG: Ibandronate|DRUG: Risedronate|DRUG: Raloxifene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BIOLOGICAL: Autologous Umbilical Cord Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-Assisted Provision of Reproductive Health Care
Status: COMPLETED
Conditions: Contraception|Sexually Transmitted Diseases
Interventions: OTHER: computer-assisted provision of hormonal contraception|OTHER: STI module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Feasibility Evaluation of the AccuCinch® Ventricular Restoration System in Patients With Heart Failure and Reduced Ejection Fraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Cardiomyopathy, Dilated
Interventions: DEVICE: AccuCinch® Ventricular Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Efficacy Evaluation of IM19 CAR-T Cells (IM19CAR-T)
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: IM19 CAR-T|DRUG: fludarabine and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Clamp Study to Prove Hypo- and Hyperglycemic Episodes Using a Non-invasive Glucose Monitoring Device
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Non-invasive CGMS (continuous glucose monitoring system)|PROCEDURE: Hyperglycemic and hypoglycemic glucose clamp|DEVICE: Non-invasive CGMS (GlucoDay)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Effects of Thiazolidinediones in Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Hormone Receptor Positive Breast Carcinoma|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: sitagliptin|DRUG: metformin|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Digital Rehabilitation System With Wearable Multi-IMU (Inertial Measurement Unit) Sensors on Upper Limb Functions in Children With Brain Injury
Status: COMPLETED
Conditions: Cerebral Palsy|Children With Brain Injury
Interventions: DEVICE: digital rehabilitation system with wearable multi-IMU(inertial measurement unit) sensors (Rapael kids)|OTHER: Conventional OT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
Status: UNKNOWN
Conditions: COPD Exacerbation|Oxygen Toxicity|Abdominal Obesity|Surgery
Interventions: OTHER: Washout period|DEVICE: NIV - FreeO2|DEVICE: Nasal High flow Oxygen therapy - FreeO2|OTHER: CPAP - Oxygen constant flow|OTHER: CPAP - FreeO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Probiotic K10 in Managing Health Outcomes in Parkinson and Alzheimer Disease
Status: COMPLETED
Conditions: Parkinson Disease|Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Probiotic K10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhancing Physical Activity Adherence After Breast Cancer Diagnosis (BEAT Cancer II)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Experimental 1: exercise with 2 counseling types|OTHER: Usual Care - written materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiation Versus Surgery With Adjuvant Therapy in Advanced Laryngopharyngeal Cancers
Status: TERMINATED
Conditions: Larynx Neoplasms
Interventions: RADIATION: Concurrent Chemoradiation|PROCEDURE: Laryngectomy + adjuvant radiotherapy/chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of COVID-19 Vaccine in Hematopoietic Stem Cell Transplant Patients
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation (HSCT)|COVID-19 Vaccines|Immune System Tolerance
Interventions: BIOLOGICAL: Pasocovac vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of Booster Vaccination With Medium-dosage or High-dosage SARS-CoV-2 Inactivated Vaccine for Prevention of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: High-dosage SARS-CoV-2 vaccine|BIOLOGICAL: Medium-dosage SARS-CoV-2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures
Status: COMPLETED
Conditions: Partial Seizures
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-man Dose Escalation Study of BAY1179470 in Patients With Advanced, Refractory Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAY1179470
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Relative Motion Splint and Metacarpophalangeal Joint Blocking Splint for Trigger Finger
Status: RECRUITING
Conditions: Trigger Finger|Stenosing Tenosynovitis
Interventions: OTHER: Relative Motion Splint|OTHER: Metacarpophalangeal Joint Blocking Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma
Status: WITHDRAWN
Conditions: Dedifferentiated Liposarcoma
Interventions: DRUG: IPI-504
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Sensori-Motor Rhythm Activity by EEG-Neurofeedback to Reduce the Impact of Pain on Daily Functioning
Status: COMPLETED
Conditions: Chronic Pain Syndrome|Peripheral Neuropathic Pain
Interventions: OTHER: EEG-based neurofeedback for brain activity modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Optimal Dose of 68Ga-OPS202 as a PET (Positron Emission Tomography) Imaging Agent in Subjects With Gastroenteropancreatic Neuroendocrine Tumour (GEP-NET)
Status: COMPLETED
Conditions: Gastro-Enteropancreatic Neuroendocrine Tumor
Interventions: DRUG: Satoreotide trizoxetan 5-20μg|DRUG: Satoreotide trizoxetan 30-45μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of CV4 and Sacral Technique on the Alpha Bands Power
Status: COMPLETED
Conditions: Healthy|Osteopathic Manipulation
Interventions: OTHER: CV4|OTHER: ST|OTHER: Sham CV4|OTHER: Sham ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Status: NOT_YET_RECRUITING
Conditions: Defect
Interventions: DRUG: Metformin Hydrochloride Sustained-release Tablets|PROCEDURE: Vaginal repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial
Status: COMPLETED
Conditions: Elderly|Older Adults|Bone Fracture|Emergency Department|Pain, Acute
Interventions: OTHER: Implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Peer Support Intervention for Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematopoietic Neoplasms|Hematopoietic Malignancy
Interventions: BEHAVIORAL: STEPP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Losartan for the Treatment of Pediatric NAFLD
Status: TERMINATED
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Losartan potassium|DRUG: Placebo losartan capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of a New Type of Pelvic Floor Rehabilitation Device PHENIX U4+ on the Treatment of Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DEVICE: PHENIX U4+|DEVICE: Traditional pelvic floor treatment instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Clinical Trial of the Misago™ Self-Expanding Stent System for Superficial Femoral Artery
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Misago™ Self-Expanding Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Development of a Virtual Reality Program to Improve Attention in Individuals With TBI
Status: UNKNOWN
Conditions: TBI (Traumatic Brain Injury)
Interventions: BEHAVIORAL: Virtual Reality Executive Function Training (VREFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing One-stage With Two-stage Basilic Vein Transposition
Status: TERMINATED
Conditions: Brachiobasilic Arteriovenous Fistula
Interventions: PROCEDURE: Transposition of the basilic vein and anastomosis with the brachial vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Placebo Controlled Study to Assess the Efficacy on Joint Damage in RA Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tacrolimus|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: DRUG: Intralipid 20%|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: alvocidib|DRUG: irinotecan hydrochloride|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: aleglitazar|DRUG: placebo|DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Prevention, Intervention and Mechanisms of Obesity and Its Comorbidities
Status: UNKNOWN
Conditions: Obesity|Exercise|Nutrition, Healthy
Interventions: BEHAVIORAL: Complex lifestyle intervention|DIETARY_SUPPLEMENT: Carnosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sleep Quality, Stress, Depression, Blood Pressure Responses to Diaphragmatic Respiratory Exercise in Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: BEHAVIORAL: Tele-supervised diaphragmatic respiratory exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Nicotine Cigarettes Plus Electronic Cigarettes
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Dependence
Interventions: OTHER: Normal Nicotine Content research cigarettes|OTHER: High Nicotine e-cigarette|OTHER: Very Low Nicotine Content research cigarettes|OTHER: Zero Nicotine e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJV Investigational Multifocal Contact Lens|DEVICE: ACUVUE OASYS® with HYDRACLEAR® PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration
Status: COMPLETED
Conditions: Anesthetics, Local|Blepharoplasty|Age-Related Ptosis|Adult|Humans|Lidocaine|Ophthalmologic Surgical Procedure|Vibration|Surgery
Interventions: DEVICE: Vibration|OTHER: Tapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate for Attention Problems After Pediatric TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury|TBI|ADHD
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Novel Multivitamin-Mineral Supplement in Preventing Vitamin Deficiency in Postoperative Bariatric Patients
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DIETARY_SUPPLEMENT: AquaVanta Chewable Tablet|DIETARY_SUPPLEMENT: Flinstones Complete|DIETARY_SUPPLEMENT: Nature Made Calcium Softgels|DIETARY_SUPPLEMENT: Nature Made Calcium Softgels|DIETARY_SUPPLEMENT: Twin Labs Iron Caps|DIETARY_SUPPLEMENT: Rexall Vitamin B12 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients
Status: NOT_YET_RECRUITING
Conditions: Dilation|Pupil Reaction Absent
Interventions: DEVICE: MydCombi Device|DRUG: MydCombi Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH