pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Motivational Interviewing on Risky Injecting Practices Among Injecting Drug Users (IDUs)
Status: COMPLETED
Conditions: HIV|Hepatitis C
Interventions: BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Methadone Versus Placebo for the Control of Neuropathic Pain in Different Etiologies
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: methadone tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wells and Enteric Disease Transmission
Status: RECRUITING
Conditions: Diarrhea|Gastrointestinal Infection|Respiratory Viral Infection|Waterborne Diseases
Interventions: DEVICE: Active UV Device|DEVICE: Inactive UV Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cannabis Versus Oxycodone for Pain Relief
Status: COMPLETED
Conditions: Back Pain|Neck Pain
Interventions: DRUG: Cannabis|DRUG: Oxycodone|DRUG: Placebo for Cannabis|DRUG: Placebo for Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fingolimod (FTY720) in Acute Demyelinating Optic Neuritis (ADON)
Status: TERMINATED
Conditions: Acute Demylelinating Optic Neuritis
Interventions: DRUG: Fingolimod 0.5mg/daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavior Change Family Counseling to Reduce Rate of Weight Gain in At-Risk Children
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Obesity
Interventions: BEHAVIORAL: Single behavior intervention|BEHAVIORAL: Multiple behavior interventions|BEHAVIORAL: Control Intervention unrelated to weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Breathing, Relaxation, Attention Training, & Health in Older Adults (BREATHE)
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Healthy Aging
Interventions: BEHAVIORAL: RFB|BEHAVIORAL: VSOP|BEHAVIORAL: IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eight-week Effect of the Sit-to-stand Test on Muscle Architecture.
Status: COMPLETED
Conditions: Quality of Life|Quality Muscle|Arquitecture Muscle
Interventions: OTHER: Group 5 STS|OTHER: Group 10 STS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effects of Mulligan Straight Leg Raise Technique Versus Slump Stretching on Pain, Disability and Hip Range of Motion in Patients With Chronic Low Back Pain.
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: OTHER: Mulligan Traction Straight Leg Raise Technique|OTHER: Slump Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy
Status: RECRUITING
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: Transapical beating-heart septal myectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of R-CHOP + Azacytidine in Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: vincristine|DRUG: doxorubicin|DRUG: prednisone|DRUG: azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of OCZ103-OS in Combination With Standard of Care in Stage IV Non-Small Cell Lung Cancer (NSCLC) Patients
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: OCZ103-OS|DRUG: Platinum|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Oculo-motor Deficiencies Associated With FMR1 Gene Expression (Genetic Abnormality Predisposing to a Neurodegenerative Disease)
Status: TERMINATED
Conditions: Pre-mutation on FMR1 Gene
Interventions: OTHER: examination of ocular movements|OTHER: MATTIS test|OTHER: UPDRS test|OTHER: CRST test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients
Status: COMPLETED
Conditions: Infertility|Polycystic Ovarian Syndrome
Interventions: DRUG: Estradiol valerate|DRUG: Sequential Clomiphene citrate and Gonadotropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Intrapleural Urokinase and Video-Assisted Thorascopic Surgery in the Treatment of Parapneumonic Pleural Effusion in Children
Status: UNKNOWN
Conditions: Empyema, Pleural
Interventions: DRUG: insertion of a chest drain with urokinase instillation|PROCEDURE: primary video-assisted thorascopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Airway Physiology In Adults. SERETIDE DISKUS® Inhaler and FLIXOTIDE® Inhaler Are Trademarks of GSK Croup of Companies.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/fluticasone propionate and fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial of NanoDOX Hydrogel in Orthopedic Trauma Wounds With and Without Vacuum Assisted Closure Therapy
Status: WITHDRAWN
Conditions: Orthopedic Trauma Wounds
Interventions: DRUG: NanoDOX Hydrogel|OTHER: VAC Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Mucograft® to Treat Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Mucograft|PROCEDURE: Connective Tissue Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prolonged Effect of Consumption of a Partially Hydrolyzed Infant Formula During the First 6 Months of Life on the Development of Allergic Manifestations at 5 Years of Age
Status: ENROLLING_BY_INVITATION
Conditions: Allergy
Interventions: OTHER: No intervention is used in the current study. Interventions were given in the original A.R.T. study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Directed Imagery Technique Applied to Patients Undergoing Lumbar Disc Herniation Surgery
Status: UNKNOWN
Conditions: Intervertebral Disc Disorder Lumbar With Radiculopathy|Surgical or Other Invasive Procedure on Wrong Patient|Nurse-Patient Relations
Interventions: BEHAVIORAL: Directed Imagery Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter Phase 2 Study of Ibrutinib in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) With 17p Deletion
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia With 17p Deletion|Small Lymphocytic Lymphoma With 17p Deletion
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Device for Treatment of Lymphedema of the Upper Extremity
Status: NOT_YET_RECRUITING
Conditions: Lymphedema|Lymphedema Arm|Lymphedema of Upper Arm
Interventions: DEVICE: LymphaVibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Sodium Tension Headache Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen Sodium|DRUG: Standard Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-263 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Exposure Prophylaxis for Transgender Women in the US and South America
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Prevention
Interventions: DRUG: Immediate Intervention Arm Truvada in the US|DRUG: Deferred Intervention Arm Truvada in the US|DRUG: Immediate Intervention Arm Truvada in Brazil|DRUG: Deferred Intervention Arm Truvada in Brazil|DRUG: Immediate Intervention Arm Descovy in the US|DRUG: Deferred Intervention Arm Descovy in the US
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: LIK066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy
Status: COMPLETED
Conditions: Post-Prandial Hyperglycemia|Post-Prandial Hypoglycemia
Interventions: DEVICE: DiAS|DRUG: Afrezza low dose|DRUG: Afrezza high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
Status: NOT_YET_RECRUITING
Conditions: Suicidal Ideation|Suicide Attempt|Self Harm
Interventions: DEVICE: Jaspr App
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre and Per-operative Electrophysiological Cartography of Speech Area With Cortical Electrode Matrices
Status: UNKNOWN
Conditions: Tumoral or Epileptical Cortectomy
Interventions: DEVICE: ECoG and intracortical electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
Status: COMPLETED
Conditions: Hip Fractures|Anesthesia Local|Pain, Postoperative
Interventions: DRUG: Lidocaine-adrenaline added gadolinium.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer
Interventions: BIOLOGICAL: Denosumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes
Status: RECRUITING
Conditions: Premature Rupture of Membrane
Interventions: DRUG: Erythromycin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Brain Radiotherapy Versus Volumetric Modulated Arc Therapy for Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: RADIATION: Single-fraction radiotherapy|RADIATION: Whole-brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intact GLP-1 (7-36) and GLP-1 Metabolite (9-36) on Coronary and Peripheral Vascular Function in Adults
Status: COMPLETED
Conditions: Coronary Microvascular Dysfunction
Interventions: DRUG: GlucagonLikePeptide-1 (7-36)|DRUG: GlucagonLikePeptide-1 (9-36)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Effect of L. Reuteri on Biomarkers of Inflammation in Healthy Infants With Colic
Status: COMPLETED
Conditions: Gastrointestinal|Colic
Interventions: BIOLOGICAL: Lactobacillus reuteri|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus TACE Versus Sorafenib Alone as Postoperative Adjuvant Treatment for Resectable Primary Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|PROCEDURE: Transarterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Chromoendoscopy and Conventional Colonoscopy to Improve the Detection of Neoplasia in Patients With Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DEVICE: conventional white light colonoscopy|DEVICE: FICE (Fujinon Intelligent Chromoendoscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lavender Oil Inhalation Help to Overcome Dental Anxiety Among Children
Status: COMPLETED
Conditions: Dental Anxiety|Anxiety Disorder|Aromatherapy
Interventions: OTHER: Anxiety scale|OTHER: Pain scale - 1|OTHER: Pain scale - 2|BEHAVIORAL: Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating GAP-486 in Non-sustained Ventricular Tachycardia
Status: TERMINATED
Conditions: Arrhythmias
Interventions: DRUG: Double-blind investigational anti-arrhythmic|DRUG: GAP-486
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Non-Drug Study Detecting And Quantifying Nocturnal Scratch Behaviors From Wrist Actigraphy Data In Adult Healthy Volunteers And Participants With Atopic Dermatitis (AD)
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DEVICE: Wrist Actigraphy Device|DEVICE: Sleep Headband
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Practice-Based Learning to Predict Polyp Histology at Colonoscopy
Status: COMPLETED
Conditions: Colonic Polyps|Adenomatous Polyps
Interventions: BEHAVIORAL: Ex vivo module|BEHAVIORAL: In vivo practice-base learning phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis
Status: COMPLETED
Conditions: Mydriasis|Dilation
Interventions: DRUG: Phentolamine Mesylate Ophthalmic Solution 1%|OTHER: Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture/Moxibustion for Peripheral Neuropathy in HIV
Status: COMPLETED
Conditions: Peripheral Neuropathies|HIV Infections
Interventions: PROCEDURE: Acupuncture/Moxibustion|OTHER: Sham acupuncture/Placebo moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Meditation and Kundalini Yoga for Heightened Anxiety Related to COVID-19
Status: UNKNOWN
Conditions: Generalized Anxiety|Health Anxiety
Interventions: BEHAVIORAL: Anxiety Reduction Training|BEHAVIORAL: Kundalini Yoga and Anxiety Reduction Training|BEHAVIORAL: Meditation and Anxiety Reduction Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects and Mechanism of the Sequential Combination of Exercise and Cognitive Training in Stroke Patients
Status: COMPLETED
Conditions: Stroke Patients With Cognitive Decline
Interventions: BEHAVIORAL: aerobic exercise training|BEHAVIORAL: control training|BEHAVIORAL: cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base
Status: COMPLETED
Conditions: Thumb Osteoarthritis
Interventions: OTHER: PRP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial GOFL in Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: oxaliplatin|DRUG: gemcitabine|DRUG: 5-FU/LV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation in Methamphetamine and STIs (IMSTI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Methamphetamine-dependence|Rectal Gonorrhea|Rectal Chlamydia
Interventions: BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Ancillary Study Protocol to GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age"
Status: COMPLETED
Conditions: Malaria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Turmeric Effect on Reduction of Serum Prolactin and Related Hormonal Change and Adenoma Size in Prolactinoma Patients
Status: UNKNOWN
Conditions: Hyperprolactinoma
Interventions: DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Synchronized Cardiac Support in Cardiogenic Shock Patients
Status: NOT_YET_RECRUITING
Conditions: Cardiogenic Shock|Extracorporeal Membrane Oxygenation|ECLS|VA ECMO
Interventions: DEVICE: Synchronized Cardiac Support with the icor kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS
Status: TERMINATED
Conditions: COVID-19|ARDS
Interventions: DRUG: Losartan 50 mg and Spironolactone 25 mg pillules oral use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the HafifMod Programme on Interdialytic Weight Gain in Hemodialysis Patients
Status: ENROLLING_BY_INVITATION
Conditions: End-Stage Renal Disease|Hemodialysis|Interdialytic Weight Gain
Interventions: BEHAVIORAL: HafifMod Programme|BEHAVIORAL: Distribution of printed material
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate|DRUG: Sulfamethoxazole-Trimethoprim|DRUG: Dapsone|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CircumVent Project: A CPAP/O2 Helmet Solution for Non-Invasive Ventilation Among Patients With COVID-19
Status: UNKNOWN
Conditions: SARS-CoV-2 Acute Respiratory Disease|COVID-19 Respiratory Infection
Interventions: DEVICE: CPAP helmet|OTHER: Standard of care non-helmet based CPAP ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perianal Versus Endoanal Application of Glyceryl Trinitrate 0.4% Ointment for Chronic Anal Fissure
Status: COMPLETED
Conditions: Chronic Anal Fissure
Interventions: DRUG: Rectogesic® (glyceryl trinitrate 0.4% ointment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Nelfilcon A contact lens|DEVICE: Etafilcon A contact lens|DEVICE: FID 107027 solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Equecabtagene Autoleucel Injection|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of (α1Proteinase Inhibitor, α1PI) in HIV Disease
Status: TERMINATED
Conditions: HIV Disease
Interventions: BIOLOGICAL: α1 Proteinase Inhibitor|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients
Status: COMPLETED
Conditions: Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant
Interventions: DRUG: RAD001|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessement of the Soothing Effect of a Food Supplement on Sensitive and Reactive Skin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Coriander Seed Oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia|Adult Myelodysplastic Syndrome
Interventions: DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of Recombinant Activated Factor VII in Subjects With Traumatic Brain Injury
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Trauma
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dacarbazine and Carmustine in Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma Metastatic
Interventions: DRUG: Dacarbazine|DRUG: Carmustine|DRUG: Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Antiplatelet Therapy in Interventional Treatment of Intracranial Aneurysms
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DRUG: Adjustment of Antiplatelet Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Laser Therapy on Facial Motor Functions Function and Synkinesis in Patients With Bell's Palsy
Status: RECRUITING
Conditions: Bell's Palsy
Interventions: OTHER: Low level laser therapy and conventional therapy|PROCEDURE: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Korean Multicenter Randomized Controlled Trial (RCT) of Pidogul for Patients With Coronary Stenting
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: clopidogrel napadisilate + aspirin|DRUG: clopidogrel bisulfate + aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOX/Bevacizumab +/- MK-0646 in Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: MK-0646|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies
Status: COMPLETED
Conditions: Infertility|Ovarian Stimulation
Interventions: DRUG: Recombinant Human-Luteinizing Hormone (Luveris)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Diffuse Scar in Patients With Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Emotional Resilience Training on Fear of Birth and Depression in Primiparous Pregnant Women
Status: ENROLLING_BY_INVITATION
Conditions: Fear of Childbirth|Depression
Interventions: OTHER: Emotional Resilience training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Mild Intermittent Asthma to Assess the Topical Safety and Tolerability of Albuterol Sulfate Acu-30™ DPI
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: Albuterol sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cryoballoon Pulmonary Vein Isolation vs. Radiofrequency Pulmonary Vein Isolation With Additional Right Atrial Linear Ablation for Valvular Atrial Fibrillation: Prospective Randomized Trial (CRAVA Trial)
Status: NOT_YET_RECRUITING
Conditions: Valvular Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon Pulmonary Vein isolation|PROCEDURE: Radiofrequency Pulmonary Vein isolation and Additional Right Atrial linear ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Four Hyaluronic Acid Fillers for Lip Augmentation
Status: COMPLETED
Conditions: Lip
Interventions: PROCEDURE: Cosmetic lip augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Intravenous naloxone|DRUG: Intranasal naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uncemented Compared to Cemented Femoral Stems in Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: PROCEDURE: Uncemented femoral stem|PROCEDURE: Cemented femoral stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol for Opioid Addiction
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Placebo|DRUG: Cannabidiol (CBD) 200mg|DRUG: Cannabidiol (CBD) 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical Trial of Neurostem®-AD
Status: UNKNOWN
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurodegenerative Diseases|Delirium, Dementia, Amnestic, Cognitive Disorders|Mental Disorders
Interventions: BIOLOGICAL: NEUROSTEM®-AD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Capsule and Tablet Formulations of TA-8995
Status: COMPLETED
Conditions: Dyslipidaemia
Interventions: DRUG: TA-8995|DRUG: TA-8995
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Neoplasm Metastasis
Interventions: DRUG: Capecitabine|PROCEDURE: Pelvic radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Telmisartan as Telmisartan 80 mg/HCTZ 12.5 mg Fixed-dose Combination Tablet or as Two Telmisartan 40 mg Tablets in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan/HCTZ combination|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Fatigue on Trunk Motor Control and Brain Activity
Status: COMPLETED
Conditions: Muscle Fatigue|Mental Fatigue|Event-related Potentials
Interventions: BEHAVIORAL: Control condition|BEHAVIORAL: Rapid Arm Movements|BEHAVIORAL: Physical fatigue condition|BEHAVIORAL: Cognitive fatigue condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analytical Performances and Clinical Impact of the Roche Cobas® Liat Influenza A/B & RSV Assay in the Management of Adult and Pediatric Patients Attending the Emergency Room
Status: TERMINATED
Conditions: Influenza Viral Infections|RSV Infection
Interventions: DIAGNOSTIC_TEST: Roche Cobas® Liat Influenza A/B & RSV assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Acupressure on Menopausal Symptoms
Status: COMPLETED
Conditions: Menopause|Acupressure
Interventions: BEHAVIORAL: acupressure|BEHAVIORAL: Sham acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Melanoma
Interventions: DRUG: Peginterferon alfa-2b|DRUG: Temozolomide|DRUG: Recombinant interferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Feasibility of a Physical Activity (Tele)Coaching Intervention in Patients With Non-small Cell Lung Cancer: an Explorative Study
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Non-small Cell Carcinoma
Interventions: DEVICE: Automated Coaching Program (ACP)|OTHER: Manual Coaching Program (MCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiology Research Dubrava Prospective Registry
Status: RECRUITING
Conditions: Heart Failure|Arrhythmias, Cardiac|Atrial Fibrillation|Acute Coronary Syndrome
Interventions: OTHER: SGLT-2 inh therapy, CIED implantation, thromboaspiration,
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Efficacy and Safety of XC221 in the Treatment of Influenza and Other Acute Respiratory Viral Infections
Status: COMPLETED
Conditions: Acute Respiratory Viral Infections|Influenza
Interventions: DRUG: XC221 100 mg|DRUG: XC221 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: DSP-7888
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simulator Practice on Trainees' Endoscopic Retrograde Cholangiopancreatography (ERCP) Performance in the Early Learning Period
Status: COMPLETED
Conditions: Patients Undergoing ERCP Examination
Interventions: DEVICE: simulator training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma (RCC)|Clear-cell Renal Cell Carcinoma|Papillary Renal Cell Carcinoma|Kidney Neoplasms|Metastatic Renal Cell Carcinoma|Ovarian Clear Cell Carcinoma
Interventions: DRUG: CDX-014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Proximal Approach and Distal Approach of Axillary Vein Catheterization Under Ultrasound Guidance
Status: COMPLETED
Conditions: Central Venous Catheterization
Interventions: PROCEDURE: The distal approach|PROCEDURE: The proximal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Midodrine Versus Albumin for Prevention of Paracentesis Induced Circulatory Disturbance
Status: COMPLETED
Conditions: Paracentesis-Induced Circulatory Dysfunction
Interventions: DRUG: Midodrine Hydrochloride|DRUG: Human Albumin 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effect of Cervical Mucus Cleaning Method Applied Before Embryo Transfer on Pregnancy Rates.
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Cotton swab|PROCEDURE: Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography Versus Palpation for Spinal Anesthesia in Obese Parturients Undergoing Cesarean Delivery
Status: COMPLETED
Conditions: Anesthesia, Spinal|Cesarean Section|Spinal Ultrasound
Interventions: RADIATION: Lumbar Spinal Ultrasonography|RADIATION: Sham Ultrasound Procedure|PROCEDURE: Conventional Landmark Palpation|PROCEDURE: Spinal Anesthesia|DRUG: Intrathecal Bupivacaine|DRUG: Intrathecal Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Eylea (Intravitreal Aflibercept, VEGF Trap-Eye, BAY86-5321)|DRUG: Eylea (Intravitreal Aflibercept, VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WAVE Study- Walking and Aging in VErona Study
Status: UNKNOWN
Conditions: Abdominal Obesity|Metabolic Syndrome|Disability Physical|Sarcopenic Obesity|Hypertension|Overweight and Obesity|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Diet|BEHAVIORAL: Walking|BEHAVIORAL: Nordic Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dinoprostone (Propess) in the Women With Premature Rupture of Membrane or Gestational Age <38
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DRUG: Propess insertion group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose of Ticagrelor and Standard-dose Clopidogrel on Platelet Effects in Chinese Patients With Stable CAD.
Status: COMPLETED
Conditions: Platelet Reactivity
Interventions: DRUG: low-dose ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A for Neuroma Pain
Status: WITHDRAWN
Conditions: Neuroma
Interventions: DRUG: onabotulinum toxin type-A|OTHER: placebo|DRUG: 2nd phase - onabotulinum toxin type-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Parameters of NNG-DEPO (Stimus) With Aranesp® (Amgen) in Treatment of Anemia in CKD Patients on Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease
Interventions: BIOLOGICAL: Stimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone in Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Dexamethasone 4mg|DRUG: Dexamethasone 8 Mg/mL Injectable Suspension|DRUG: Dexamethasone 16mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Ipilimumab After Isolated Limb Perfusion, in Patients With Metastases Melanoma
Status: COMPLETED
Conditions: In-transit Metastases Melanoma Stage IIIB and IIIC
Interventions: DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of QVA149 Versus NVA237 and Tiotropium on Chronic Obstructive Pulmonary Disorder (COPD) Exacerbations
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QVA149|DRUG: NVA237|DRUG: tiotropium|DRUG: Salbutamol/albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic Challenges From Mild Hypovolemia and Mechanical Ventilation
Status: COMPLETED
Conditions: Autonomic Nervous System Imbalance|Hypovolemia|Positive-Pressure Respiration
Interventions: OTHER: Increase of central volume|OTHER: Ventilation mode
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP)
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Black raspberry (BRB) Slurry|DRUG: Black Raspberry (BRB) Suppositories|DRUG: Black Raspberry (BRB) Placebo Slurry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose-response Evaluation of ALK (the Sponsor) Tree Allergy Immunotherapy Tablet
Status: COMPLETED
Conditions: Birch Pollen Allergy
Interventions: BIOLOGICAL: ALK tree AIT 0.5 DU|BIOLOGICAL: ALK tree AIT 1 DU|BIOLOGICAL: ALK tree AIT 2 DU|BIOLOGICAL: ALK tree AIT 4 DU|BIOLOGICAL: ALK tree AIT 7 DU|BIOLOGICAL: ALK tree AIT 12 DU|BIOLOGICAL: ALK tree AIT Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Cancer of Rectum|Cancer of the Rectum|Neoplasms, Rectal|Rectal Tumors|Rectum Cancer|Rectum Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
Status: RECRUITING
Conditions: Breast Screening
Interventions: PROCEDURE: Digital Mammography|PROCEDURE: Digital Tomosynthesis Mammography|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Assess Duration of Indwelling Catheter After Sacrocolpopexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Tract Infections|Urinary Retention
Interventions: PROCEDURE: Immediate catheter removal|PROCEDURE: Post op day 1 catheter removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-label Study on the Clinical Efficacy of rTMS Intervention in PD
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Parkinson Disease|Supplementary Motor Area
Interventions: OTHER: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Neuromuscular Electrical Stimulation|ICU Acquired Muscle Weakness
Interventions: PROCEDURE: Exercise group|PROCEDURE: Neuromuscular Electrical Muscle Stimulation group|PROCEDURE: Neuromuscular Electrical Muscle Stimulation and Exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using BCG Vaccine to Protect Health Care Workers in the COVID-19 Pandemic
Status: COMPLETED
Conditions: COVID-19|Non-specific Effects of Vaccines|Morbidity|Absenteeism|Heterologous Immunity
Interventions: BIOLOGICAL: BCG-Denmark|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First Clinical Evaluation of Heart Transplantation With Grafts Preserved Using an Ex-vivo Extended Perfusion System
Status: NOT_YET_RECRUITING
Conditions: Heart Transplantation
Interventions: PROCEDURE: Heart transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Adding Dexamethasone to Bupivacaine 0.25% in SCPB on Surgical Field Visibility During Tympanomastoid Surgery
Status: NOT_YET_RECRUITING
Conditions: Surgical Field|Postoperative Pain
Interventions: DRUG: bupivacaine 0.25%|DRUG: dexamethasone 2 mg in bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER