pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endometrial Injury and IVF Outcome Parameters in Patients With Failed IVF Cycles
Status: COMPLETED
Conditions: Repeated Implantation Failures
Interventions: PROCEDURE: Endometrial injury by hysteroscopy or pipelle sampling|PROCEDURE: Proceed to COH directly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Nanotechnology Based Drug-Eluting Stent for Opening of Narrowed Arteries of the Heart
Status: UNKNOWN
Conditions: Coronary Stenosis
Interventions: DEVICE: drug eluting nonpolymeric nanoporous stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nursing Intervention for Knowledge and Self-care Behaviors in the Face of Hypertensive Disorders of Pregnancy
Status: COMPLETED
Conditions: Hypertensive Disorders of Pregnancy
Interventions: BEHAVIORAL: Nursing intervention to improve knowledge and self-care behaviors in the face of HDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Post-marketing Evaluation of a Compound Traditional Chinese Herbal Medicine, Qishe Pill, on Cervical Radiculopathy
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: DRUG: Qishe Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Bandage After FUE Hair Transplantation
Status: NOT_YET_RECRUITING
Conditions: Hair Loss/Baldness
Interventions: DEVICE: Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Miglustat on the Nasal Potential Difference in Patients With Cystic Fibrosis Homozygous for the F508del Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Miglustat ; placebo|DRUG: Placebo ; Miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Supported by Autologous Hematopoietic Stem Cells
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: OTHER: Autologous blood transfusion with haematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Faldaprevir, Ribavirin and TD-6450 in Participants With Genotype 4 Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C Viral Infection|Chronic Hepatitis C|Hepatitis C (HCV)|Hepatitis C Genotype 4
Interventions: DRUG: Faldaprevir|DRUG: TD-6450|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Tear
Interventions: PROCEDURE: ACL Reconstruction (Bone Patellar Tendon Bone Graft)|DEVICE: Bridge Enhanced ACL Restoration (BEAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Bimatoprost Effect on Androgen Dependent Hair Follicles
Status: COMPLETED
Conditions: Male Pattern Hair Loss|Androgenetic Alopecia
Interventions: DRUG: Bimatoprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aborption and Metabolism of Lyophilized Black Raspberry Food Products in Men With Prostate Cancer Undergoing Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: DRUG: lyophilized black raspberry confection|OTHER: laboratory biomarker analysis|DIETARY_SUPPLEMENT: dietary intervention|DIETARY_SUPPLEMENT: dietary intervention|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bavituximab Plus Carbo and Pemetrexed in Chemo-Naive Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) Subjects
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Bavituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiology of GIP(1-30)NH2 in Humans
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: OTHER: GIP(1-30)NH2|OTHER: GIP(1-42)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of SPG302 in Adults With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: SPG302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Crystalloids With Different SID on pH, and Urinary Electrolytes During General Anesthesia
Status: COMPLETED
Conditions: SID|Acid-Base Imbalance
Interventions: OTHER: 0.9% saline administration|OTHER: Ringer's lactate administration|OTHER: Plasmalyte-like solution administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pegfilgrastim and Darbepoetin Alfa in Support of Adjuvant Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Stage I Breast Cancer|Stage II Breast Cancer
Interventions: DRUG: Darbepoetin Alfa|DRUG: Pegfilgrastim|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Vinorelbine Tartrate Injectable Emulsion in Patients With Advanced Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Non-small Cell Lung Cancer|Non-Hodgkins Lymphoma
Interventions: DRUG: Vinorelbine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Multidisciplinary, Multimodality, But Minimalist Approach to Transfemoral Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: OTHER: Vancouver 3M Clinical Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Alcohol Skin Solutions in Fractured Extremities
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Site Infection|Unplanned Fracture-Related Reoperation|Open Appendicular Fracture|Closed Lower Extremity Fracture|Pelvic Fracture
Interventions: DRUG: DuraPrep|DRUG: ChloraPrep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study In Healthy Subjects To Evaluate The Changes In The Protein sAPP-Alpha In Cerebrospinal Fluid Following A Single Oral Dose Of PF-04995274
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04995274|DRUG: PF-04995274
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ventricular Catheter Ablation Study (VCAS)
Status: RECRUITING
Conditions: Ventricular Tachyarrhythmia|Ventricular Arrythmia|PVC - Premature Ventricular Complex|PVC - Premature Ventricular Contraction|Ventricular Tachycardia
Interventions: DEVICE: FieldForce™ Ablation System Ventricular Tachycardia|DEVICE: FieldForce™ Ablation System Premature Ventricular Contractions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Adjustable Gastric Banding With Truncal Vagotomy
Status: TERMINATED
Conditions: Morbid Obesity|Obstructive Sleep Apnea|Hypertension|Urinary Incontinence|Hypertriglyceridemia|Diabetes|Hypercholesterolemia
Interventions: PROCEDURE: Laparoscopic Truncal Vagotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the Elderly
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Venetoclax in Combination With Azacitidine and HA Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents
Status: COMPLETED
Conditions: Syncope, Vasovagal
Interventions: DRUG: metoprolol|DRUG: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Expanded NK Cells Infusion Decrease Relapse Post Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Hematologic Malignancy
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy (SBRT) for Spinal/Para-Spinal Metastases (Spine SBRT)
Status: COMPLETED
Conditions: Spinal Metastases
Interventions: RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Moringa Oleifera Leaf on Hemoglobin Levels in Anemia
Status: COMPLETED
Conditions: Anemia of Pregnancy
Interventions: DIETARY_SUPPLEMENT: Moringa oleifera capsules|DIETARY_SUPPLEMENT: iron and folic acid supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Safety Study of Oxfendazole
Status: WITHDRAWN
Conditions: Tenia Solium Infection
Interventions: DRUG: oxfendazole|DRUG: placebo|DRUG: oxfendazole|DRUG: oxfendazole|DRUG: oxfendazole|DRUG: oxfendazole|DRUG: oxfendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Odanacatib (0822-059)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Odanacatib|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Tarceva|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Gallstones
Interventions: PROCEDURE: minimally invasive cholecystolithotomy with gallbladder reservation|PROCEDURE: laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT)
Status: COMPLETED
Conditions: Supra-ventricular Tachycardia
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methods to Enhance AZR-MD-001 for Meibomian Gland Dysfunction (MGD)
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DRUG: AZR-MD-001 ointment/semi-solid drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis
Status: COMPLETED
Conditions: HIV Infection|Tuberculosis
Interventions: OTHER: Strategy: Immediate ART|OTHER: Strategy: Deferred ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
Status: COMPLETED
Conditions: Airway Obstruction|Apnea|Hypopnea
Interventions: DEVICE: Airway Management System (AMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Sirolimus|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Perception Comparison of Computerized vs Conventional Injection Methods
Status: RECRUITING
Conditions: Pain Perception|Local Anesthesia
Interventions: DEVICE: Conventional Syringe|DEVICE: STA Single Tooth Anesthesia® System.|DEVICE: Star Pen anesthesia device.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer
Status: WITHDRAWN
Conditions: Advanced Liver Cancer
Interventions: BIOLOGICAL: Activated CIK and CD3-MUC1 Bispecific Antibody in Treating Liver Cancer|PROCEDURE: cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dehydroepiandrosterone in Women With Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: IOP Reduction After Anecortave Acetate Injection in Glaucoma Patients
Status: UNKNOWN
Conditions: Glaucoma|Intraocular Pressure
Interventions: DRUG: Anterior Juxtascleral Depot of Anecortave Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can MRI of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: MRT Accuracy|DIAGNOSTIC_TEST: MRT Stability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Stabilization of Hypercapnia: NIPPV v HVNI
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure|Chronic Obstructive Pulmonary Disease|Dyspnea|Hypercapnic Acidosis
Interventions: DEVICE: High Velocity Nasal Insufflation (HVNI)|DEVICE: Noninvasive Positive Pressure Ventilation (NIPPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Otago Exercise Program in Falls, Balance and Physical Performance in Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Otago Exercise Program|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroponic Fortification and Dietary App Effect on Nutrients Level (Harvest)
Status: ENROLLING_BY_INVITATION
Conditions: Iron Deficiency (Without Anemia)|B12 Deficiency Vitamin
Interventions: BEHAVIORAL: Recipes consumption|BEHAVIORAL: Hydroponic unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hemodynamic Response to Pain During Retinopathy Of Prematurity Screening
Status: RECRUITING
Conditions: Preterm
Interventions: DRUG: benoxinate hydrochloride 0.4% group|DRUG: saline 0.9% .
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Diagnostics of Functional and Organic Intestinal Pathology Based on Cellular and Molecular Profiling
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Irritable Bowel Syndrome|Healthy Volunteers
Interventions: DIAGNOSTIC_TEST: cell and molecular diagnostics in accordance with functional test results
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Lycopene on Sperm Quality in Men Attending Fertility Clinic
Status: RECRUITING
Conditions: Total Motile Sperm Count
Interventions: DIETARY_SUPPLEMENT: Lycopene|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Assessing Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter
Status: COMPLETED
Conditions: Scar-related Atrial Tachycardia|Persistent Atrial Fibrillation|Paroxysmal Atrial Fibrillation|Ventricular Tachycardia|Premature Ventricular Complex
Interventions: DEVICE: Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of APIC-PRP in Non-healing Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: APIC-PRP|OTHER: Placebo, Saline plus standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorine F 18 Sodium Fluoride PET/CT and Whole Body and Axial MRI in Finding Metastases in Patients With Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Recurrent Prostate Cancer
Interventions: PROCEDURE: computed tomography|PROCEDURE: bone scan|PROCEDURE: 3-Tesla magnetic resonance imaging|PROCEDURE: diffusion-weighted magnetic resonance imaging|RADIATION: fluorine F 18 sodium fluoride|PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Bismuth subsalicylate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Annual Study to Investigate Inactivated Virosomal Influenza Vaccine for the 2006/2007 Influenza Season in Europe.
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Trivalent virosomal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Double Blind Trial in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Suramin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carbon-14-Labelled [14C] LY3556050 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-LY3556050
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electroacupuncture for Sciatica Due to Intervertebral Disc Displacement
Status: UNKNOWN
Conditions: Sciatica Due to Intervertebral Disc Disorder
Interventions: OTHER: Electroacupuncture (EA)|OTHER: Traction|DRUG: Voltaren|DRUG: Vitamin B1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CSL Limited's Influenza Virus Vaccine in the Paediatric Population Aged >= 6 Months to < 18 Years
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CSL Limited Influenza Virus Vaccine|BIOLOGICAL: CSL Limited Influenza Virus Vaccine|BIOLOGICAL: CSL Limited Influenza Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of a Nasal Spray to Treat Children With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Azelastine hydrochloride nasal spray 0.15%|DRUG: Azelastine hydrochloride nasal spray 0.10%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Economic and Clinical Benefit of Remote Monitoring Among Defibrillator Patients by Indication Subgroups (BENEFIT-RM)
Status: RECRUITING
Conditions: Patients With Defibrillator
Interventions: DEVICE: on remote monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Outpatient Intravenous Interleukin-2 in Malignant Melanoma and Metastatic Kidney Cancer
Status: WITHDRAWN
Conditions: Melanoma|Metastatic Kidney Cancer
Interventions: DRUG: Interleukin-2 (IL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Over the Counter (OTC) Povidone-Ioldine 5% for Treatment of Acute or Chronic Blepharitis
Status: TERMINATED
Conditions: Blepharitis
Interventions: DRUG: povidone iodine|OTHER: No Intervention|DRUG: Azithromycin|DRUG: tobramycin-dexmethasone|OTHER: warm soaked eyelid wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Andecaliximab on FEV1 in Adults With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Andecaliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline Efficacy in Improving Neurological Outcome of Patients Who Undergo Endovascular Revascularization for Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Minocyclin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study for the Assessment of Silibinin (Legalon® SIL) in the Treatment of naïve Genotype 4 Patients With Chronic Hepatitis C
Status: WITHDRAWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Legalon® SIL (Silibinin)|DRUG: Pegylated interferon alfa2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Brivaracetam (BRV) on Nonpsychotic Behavioral Side Effects in Subjects Treated Previously With Levetiracetam (LEV)
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transbronchial, Cryoprobe, and VATS Biopsy for the Diagnosis of Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease
Interventions: PROCEDURE: Transbronchial biopsy|PROCEDURE: Cryoprobe biopsy|PROCEDURE: VATS biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dietary Nitrate on Plasma Nitrate Levels for Nasopharyngeal Carcinoma Patients
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DIETARY_SUPPLEMENT: nitrate supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Evaluating ABT-751 in Combination With Taxotere in Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: ABT-751|DRUG: Placebo|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Molars Restoration Using CAD/CAM Crowns.
Status: COMPLETED
Conditions: Restoration of Primary Molars With CAD/CAM Crowns
Interventions: OTHER: CAD/CAM crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Docetaxel and Gemcitabine in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Moexipril HCl 15 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moexipril HCl 15mg Tablets, Paddock Laboratories, Inc.|DRUG: Univasc® 15mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting
Status: COMPLETED
Conditions: 2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer
Interventions: BIOLOGICAL: GVAX Pancreas Vaccine|BIOLOGICAL: CRS-207|DRUG: Chemotherapy|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Performance of RFA of the Nerves Supplying the Posterior Sacroiliac Joint Complex.
Status: COMPLETED
Conditions: Osteoarthritis Nos, of Sacroiliac Joint
Interventions: PROCEDURE: Cooled RFA of sacral lateral branches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Reported Preferences Affecting Revascularization Decisions
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: OTHER: Decision-making tool for coronary artery disease treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Ibuprofen 600 mg|DRUG: Placebo Corn Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive Behavioral Treatments for Pathological Gambling
Status: COMPLETED
Conditions: Gambling
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT)|BEHAVIORAL: Contingency management (CM)|BEHAVIORAL: Psychoeducation therapy|BEHAVIORAL: Case management|BEHAVIORAL: Gamblers Anonymous (GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib With Ceralasertib in Recurrent Osteosarcoma
Status: RECRUITING
Conditions: Osteosarcoma|Osteosarcoma Recurrent
Interventions: DRUG: Olaparib|DRUG: Ceralasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-844421 for Treatment of Hypercholesterolemia
Status: TERMINATED
Conditions: Atherosclerosis|Hypercholesterolemia
Interventions: DRUG: BMS-844421|DRUG: 0.9% sodium chloride injection solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Impact on Platelet Reactivity in Acute Coronary Syndrome Patients on Novel P2Y12 Inhibitors Therapy
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Platelet Function and Reactivity Tests|Novel P2Y12 Inhibitors
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liking Adaptation to Beverages of Varying Sweetness Levels After Prolonged Exposure
Status: TERMINATED
Conditions: Sweetness Liking Adaptation
Interventions: OTHER: Flavored carbonated soft drink (CSD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GB001 in Adult Participants With Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)|Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Interventions: DRUG: GB001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula (HFNC) Versus Nasal Intermittent Mandatory Ventilation (NIMV)for Respiratory Distress Syndrome (RDS): a Randomized, Controlled, Prospective Study
Status: UNKNOWN
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: NIMV with SLE ventilator vs HFNC via Vapotherm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pasireotide LAR Administration in Lymphocele Prevention After Axillary Node Dissection for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: PASIREOTIDE|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: etanercept|DRUG: sulphasalazine (SSZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia
Status: COMPLETED
Conditions: Monomorphic Ventricular Tachycardia
Interventions: PROCEDURE: Ablation|DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Aluminium-reactive T-lymphocytes in Patients With Vaccination Granulomas
Status: COMPLETED
Conditions: Granuloma|Aluminum Allergy
Interventions: DIAGNOSTIC_TEST: Aluminum|DIAGNOSTIC_TEST: Tetanus toxoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nitric Oxide During CPB to Reduce AKI in Neonates
Status: WITHDRAWN
Conditions: Congenital Heart Disease|Acute Kidney Injury
Interventions: DRUG: NO gas delivered during cardiac surgery|OTHER: placebo gas delivered during cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Azithromycin in the Treatment of Chlamydial Conjunctivitis
Status: COMPLETED
Conditions: Chlamydial Conjunctivitis
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Test of High-fat Diet After Oral Administration of SHR2554 in Healthy Subjects
Status: COMPLETED
Conditions: Malignant Tumor
Interventions: DRUG: SHR2554|DRUG: SHR2554
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rationale for New Topical Anthroponotic Cutaneous Leishmaniasis (ACL) Treatment in Kabul
Status: COMPLETED
Conditions: Wound Healing
Interventions: OTHER: Electro-thermo-coagulation|DRUG: DAC N-055|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-Coated Nasal Balloon for the Treatment of Recurrent Chronic Rhinosinusitis With or Without Nasal Polyps (FIH)
Status: RECRUITING
Conditions: Chronic Rhinosinusitis
Interventions: COMBINATION_PRODUCT: Airiver Nasal Drug Coated Balloon (DCB) Catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patients After Cardiac Surgery: Novel Ultrasound Parameters for Quantification of Renal Perfusion & Analysis of Phenylephrines' Effect on Invasive Haemodynamics and Echocardiographic Measures
Status: COMPLETED
Conditions: Ultrasonography, Renal|Cardiac Surgery|Hemodynamics|Phenylephrine|Renal Perfusion|Echocardiography|Anesthesia
Interventions: DRUG: Phenylephrine|OTHER: Combination of PEEP and positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of Infection Control to Knee Periprosthetic Joint Infection (PJI) -United Cellbrick Knee Spacer
Status: RECRUITING
Conditions: Knee; Infection, Joint
Interventions: DEVICE: Novel spacer|DEVICE: Spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Role of Brain Molecules for Decision Making
Status: COMPLETED
Conditions: Decision Making|Healthy
Interventions: DRUG: Methylphenidate|DRUG: Reboxetine|DRUG: Nicotine gum|DRUG: Placebo pill|DRUG: Placebo gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals
Status: TERMINATED
Conditions: AIDS-related Dementia Complex
Interventions: DRUG: Darunavir|DRUG: ritonavir|DRUG: cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Aggrenox|DRUG: Aggrenox|DRUG: Clopidogrel placebo|DRUG: Clopidogrel placebo|DRUG: Micardis|DRUG: Micardis|DRUG: Aggrenox placebo|DRUG: Aggrenox placebo|DRUG: Clopidogrel|DRUG: Clopidogrel|DRUG: Micardis placebo|DRUG: Micardis placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Persistence of Effect and Safety of Valbenazine for the Treatment of Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia (TD)
Interventions: DRUG: Valbenazine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Odors on Asthma Symptoms
Status: ENROLLING_BY_INVITATION
Conditions: Asthma
Interventions: BEHAVIORAL: Therapeutic Suggestion|BEHAVIORAL: Asthmogenic Suggestion|OTHER: Phenylethyl Alcohol odor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Citicoline for the Treatment of Traumatic Brain Injury (COBRIT)
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Placebo|DRUG: citicoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of CPAP Therapy in Obstructive Sleep Apnea on Parameters of Nocturnal Pulse Wave Analysis
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: 6 months CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Supportive Text Messages for Patients With Alcohol Use Disorder and a Co-morbid Depression
Status: UNKNOWN
Conditions: Dual Diagnosis
Interventions: OTHER: Supportive text messages intervention|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
Status: COMPLETED
Conditions: Childhood Brain Neoplasm|Recurrent Childhood Brain Neoplasm
Interventions: PROCEDURE: Dynamic Contrast-Enhanced Magnetic Resonance Imaging|PROCEDURE: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging|DRUG: Ferumoxytol Non-Stoichiometric Magnetite|DRUG: Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: PF-04360365|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fluticasone and Salmeterol on Airway Dendritic Cells (DCs) in Smokers
Status: COMPLETED
Conditions: Smoke-related Lung Diseases|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: fluticasone|DRUG: fluticasone/salmeterol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relationship-Based Intervention for Post-Partum Depression
Status: RECRUITING
Conditions: Post Partum Depression
Interventions: OTHER: Post-partum depression- Dyadic psychotherapy-|OTHER: Post-partum depression- Psycho-educational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of PED With AMT and Autologous Serum
Status: COMPLETED
Conditions: Corneal Epithelial Defect
Interventions: PROCEDURE: Amniotic membrane transplantation|DRUG: Autologous serum/BSS 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversalis Fascia Plane Block for Iliac Bone Graft in Children
Status: RECRUITING
Conditions: Postoperative Pain, Acute
Interventions: PROCEDURE: transversalis fascial plane block|PROCEDURE: transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DS Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy)
Status: COMPLETED
Conditions: Prostate Cancer|Kidney Cancer|Congenital Abnormality of Kidney|Nephrolithiasis|Kidney Tuberculosis|Nephritis|Kidney Injury|Hydronephrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety Study to Assess the Effects of Therapeutic and Supratherapeutic Exenatide Concentrations on QT Interval in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Exenatide|DRUG: Moxifloxacin|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Artificial Pancreas With Carbohydrate Suggestion for Patients With Type 1 Diabetes Prone to Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus Prone to Hypoglycemia
Interventions: DEVICE: Automated Insulin Delivery System (SAFE-AP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study to Evaluate the Safety and Efficacy of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Moderate-to-Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Human Placenta-Derived Cells PDA001 Intravenous Infusion|DRUG: Vehice Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients Who Have Received First-Line Therapy for Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Hodgkin's antigens-GM-CSF-expressing cell vaccine|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Hypotensive Drugs on Mineral Status in Experimental and Clinical Studies
Status: COMPLETED
Conditions: Nutritional Disorder|Hypertension|Mineral Deficiency
Interventions: DIETARY_SUPPLEMENT: group/arm C (control group)|DIETARY_SUPPLEMENT: group/arm D (diet group)|DIETARY_SUPPLEMENT: group/arm S (supplementation group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CDX-0159 in Patients With Prurigo Nodularis
Status: COMPLETED
Conditions: Prurigo Nodularis
Interventions: BIOLOGICAL: CDX-0159|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Coaching Programme on Health Promoting Behaviours in Middle-Aged Adults With Cardiometabolic Risk
Status: UNKNOWN
Conditions: Coaching|Cardiovascular Diseases|Metabolic Diseases
Interventions: BEHAVIORAL: Health coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: PQ912|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Repaglinide and Gliclazide in Chinese Subjects With Type 2 Diabetes Never Received Oral Antidiabetic Drug Treatment
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GLWL-01
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GLWL-01, Part A|DRUG: Placebo, Part A|DRUG: GLWL-01, Part B|DRUG: Placebo, Part B|DRUG: GLWL-01, Part C|DRUG: Placebo, Part C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT