pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Fixed Dose Combination (FDC) of Olopatadine Hydrochloride and Mometasone Furoate Nasal Spray (Molo; Also Referred as GSP 301) in the Treatment of Seasonal Allergic Rhinitis (SAR)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Molo 1 (also referred as GSP 301-2 NS)|DRUG: Molo 2 (also referred as GSP 301-1 NS)|DRUG: Placebo nasal spray|DRUG: DYMISTA nasal spray|DRUG: PATANASE nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU6668 in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: orantinib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Clear Skin Formula on Mitigating Mild to Moderate Non-cystic Acne
Status: RECRUITING
Conditions: Non-Cystic Acne
Interventions: DIETARY_SUPPLEMENT: VitaMedica® Clear Skin Formula capsules|OTHER: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores
Status: COMPLETED
Conditions: Recurrent Herpes Labialis
Interventions: DRUG: Merlin|DRUG: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-care in Older Frail Persons With Heart Failure Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Self Care|Heart Failure|Frailty
Interventions: OTHER: Self-care in Older frail Persons with Heart failure Intervention (SOPHI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hepatic Function in Alcoholics Following 5 Days of Acetaminophen Dosing
Status: COMPLETED
Conditions: Alcohol Related Disorders
Interventions: DRUG: acetaminophen (4g/day)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Four-arm Mesh for Vaginal Stump Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Sexual Function Abnormal
Interventions: PROCEDURE: 4-arm polypropylene mesh surgery|DIAGNOSTIC_TEST: The Female Sexual Function Index (FSFI) questionnaire|DIAGNOSTIC_TEST: King Health Questionnaire (KHQ)|DIAGNOSTIC_TEST: Pelvic Organ Prolapse Quantification (POPQ) staging|DIAGNOSTIC_TEST: Postoperative questionnaire|DIAGNOSTIC_TEST: The Short Form Health Survey (SF 36) questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: M9466|DRUG: Irinotecan|DRUG: Folinic acid|DRUG: Fluorouracil (5-FU)|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Advance Care Planning for Persons With Early-stage Dementia in the Community: a Feasibility Trial
Status: COMPLETED
Conditions: Dementia Mild|Mild Cognitive Impairment
Interventions: BEHAVIORAL: ACP programme "Have a Say"|BEHAVIORAL: Attention-control health talks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Universal Dual-target NKG2D-NKp44 CAR-T Cells in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: Universal Chimeric Natural Killer Receptor Modified T-cells (CNK-UT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
Status: COMPLETED
Conditions: Choroidal Neovascularization Secondary to Pathologic Myopia
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Pharmacokinetics and Safety of BMS-986177 in Participants With Normal Renal Function and With Moderate or Severe Renal Impairment
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: BMS-986177
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antibody-mediated LGI1 Encephalitis: Symptoms, Biomarkers, and Mechanisms of the Chronic Phase of the Disease
Status: RECRUITING
Conditions: Limbic Encephalitis With LGI1 Antibodies
Interventions: BEHAVIORAL: Remote cognitive rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Post-Operative Cardiac Arrhythmias
Status: UNKNOWN
Conditions: Cardiac; Dysrhythmia, Postoperative|Congenital Heart Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Magnesium Sulfate|DRUG: Amiodarone|DRUG: Procainamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ulinastatin on Postoperative Renal Function in Patients Undergoing Robot-assisted Laparoscopic Partial Nephrectomy
Status: COMPLETED
Conditions: Renal Mass
Interventions: DRUG: ulinastatin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Safety and Efficacy Civamide in Osteoarthritis (OA) of the Knee(s)
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Civamide (Zucapsaicin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: Real repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-angle Glaucoma or Ocular Hypertension Patients
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: AL-12182 0.003% Ophthalmic Solution|OTHER: AL-12182 Ophthalmic Solution Vehicle|DRUG: Latanoprost 0.005% Ophthalmic Solution|DRUG: AL-12182 0.01% Ophthalmic Solution|DRUG: AL-12182 0.03% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sirolimus and Azathioprine in Lung Transplantation
Status: COMPLETED
Conditions: Delayed Graft Function|Acute Graft Rejection
Interventions: DRUG: azathioprine|DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of the Effects of Remote Preconditioning on the Tissue Metabolism During Exercise and Ischemia
Status: UNKNOWN
Conditions: Ischemia
Interventions: PROCEDURE: Real preconditioning|PROCEDURE: Sham preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Trial to Evaluate the Efficacy and Safety of BLS-ILB-E710c in Patients With Cervical Intraepithelial Neoplasia 2/3 (CIN2/3)
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3
Interventions: BIOLOGICAL: BLS-ILB-E710c|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease
Status: TERMINATED
Conditions: Mycobacterium Avium Complex|Non-tuberculous Mycobacterium Pulmonary Disease
Interventions: DRUG: SPR720|DRUG: Placebo|DRUG: Open-label Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Multimodal MRI in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease|Magnetic Resonance Imaging|Deep Brain Stimulation
Interventions: OTHER: Functional magnetic resonance imaging|DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficiency of γδ T Cell Against Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Cryosurgery , IRE surgery ,surgery|BIOLOGICAL: γδ T cells|OTHER: γδ T cells/ Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wearable Cardioverter Defibrillator in Hemodialysis Patients (WED-HED) Study
Status: TERMINATED
Conditions: Sudden Cardiac Death|Sudden Cardiac Arrest
Interventions: DEVICE: Wearable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Response and Affective States of Elderly and 50+ Individuals After Intentional and Indirect Contact With Nature
Status: UNKNOWN
Conditions: Elderly
Interventions: BEHAVIORAL: Indirect contact with nature|BEHAVIORAL: Intentional contact with nature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer
Status: WITHDRAWN
Conditions: Anorexia|Constipation, Impaction, and Bowel Obstruction|Pain|Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: nicotine|OTHER: Placebo|PROCEDURE: Quality of life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: BEHAVIORAL: Interpersonal psychotherapy for prevention with adolescents|BEHAVIORAL: Educational clinical monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebral Oxygenation During Vojta Therapy in Healthy Adults Using Near-infrared Spectroscopy
Status: UNKNOWN
Conditions: Healthy|Brain
Interventions: OTHER: Reflex locomotion stimulus|OTHER: sham stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic Hypertension
Status: COMPLETED
Conditions: Systolic Hypertension
Interventions: DRUG: LCZ696|DRUG: Valsartan|DRUG: AHU377|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Phenylephrine and Norepinephrine on Cardiac Function During Carotid Artery Surgery
Status: UNKNOWN
Conditions: Vasopressor Agents|Endarterectomy, Carotid|Echocardiography, Transesophageal
Interventions: DRUG: Comparison of Effects of Phenylephrine and Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Clinical Trial to Study the Safety and Efficacy of Chandrakanthi Choornam in Patients With Low Sperm Count
Status: COMPLETED
Conditions: Oligospermia
Interventions: DRUG: Chandrakanthi Choornam (CKC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Slow Injection of Fentanyl on the Incidence of Spinal Anesthesia Induced Itching in Cesarean Section
Status: COMPLETED
Conditions: Itching
Interventions: DRUG: (R) Rapid spinal fentanyl injection|DRUG: (S) Slow spinal fentanyl injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD)
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Myelomeningocele Study (MOMS)
Status: COMPLETED
Conditions: Meningomyelocele|Spinal Dysraphism
Interventions: PROCEDURE: Prenatal Myelomeningocele Repair Surgery|PROCEDURE: Postnatal Myelomeningocele Repair Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Fanconi Anemia
Status: TERMINATED
Conditions: Fanconi Anemia
Interventions: PROCEDURE: Hematopoietic Stem Cell Transplant|PROCEDURE: Thymic Shielding During Radiation|PROCEDURE: Total Body Irradiation|DRUG: Cyclophosphamide, Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition
Status: COMPLETED
Conditions: Children|Malnutrition
Interventions: BEHAVIORAL: Nutrition education|DIETARY_SUPPLEMENT: RUTF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBT-I Versus CBT-I+ACT for Youths With Insomnia and Anxiety
Status: RECRUITING
Conditions: Insomnia|Anxiety|Youth
Interventions: BEHAVIORAL: CBT-I|BEHAVIORAL: CBT-I combined ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Intravenous and Subcutaneous Infudopa With Intestinal Duodopa in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Infudopa i.v.|DRUG: Infudopa s.c.|DRUG: LCIG (Duodopa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Propolis Improves Glycemic Control in Subjects With Type 2 Diabetes and Chronic Periodontitis
Status: COMPLETED
Conditions: Diabetes Mellitus|Periodontitis
Interventions: DRUG: Propolis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spray Stretch Technique Versus Sustain Pressure for Trapezius Triggers
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial|Mechanical Neck Pain
Interventions: OTHER: Spray and Stretch technique (Ethyl chloride)|OTHER: Sustain pressure release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-Directed Mindfulness Meditation Intervention in Gynecologic Cancer Patients
Status: TERMINATED
Conditions: Stage III Gynecologic Cancer|Stage IV Gynecologic Cancer
Interventions: OTHER: Mindfulness meditation|OTHER: Usual care packet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of the Restriction of Sources of Gluten in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Gluten|DIETARY_SUPPLEMENT: Rice protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Progressive Functional Strength Training in Unilateral Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy
Interventions: OTHER: traditional physiotherapy|OTHER: progressive functional strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized-controlled Trial (RCT) on Combination Antibiotic for Infections Caused by Gram-negative Bacteria
Status: WITHDRAWN
Conditions: Bacteremia|Healthcare-associated Pneumonia|Ventilator-associated Pneumonia
Interventions: DRUG: Polymyxin B|DRUG: Polymyxin B + Doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patterned Electrical Neuromuscular Stimulation and Therapeutic Exercise for Osteoarthritis of the Knee: Pilot Study
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Patterned Electrical Neuromuscular Stimulation|DEVICE: Placebo PENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate a High-Fat Meal and Omeprazole Enteric-coated Tablets on ASBK021
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: ABSK021|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
Status: ACTIVE_NOT_RECRUITING
Conditions: Peyronie's Disease
Interventions: DRUG: Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH)|PROCEDURE: Penile Plication Surgery|PROCEDURE: Incision and Grafting (I&G) Surgery|DEVICE: RestoreX Penile Traction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Expression of Nitric Oxide Syntheses and Their Functional Role in Human Urothelium
Status: TERMINATED
Conditions: Interstitial Cystitis|Bladder Diseases|Urinary Incontinence
Interventions: PROCEDURE: Tissue examination for protein- and mRNA-expression of NO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Early Physiotherapy on Pain, Quality of Life, Pelvic Floor Function, and Sexual Health Post-Episiotomy
Status: NOT_YET_RECRUITING
Conditions: Gynecological; Surgery (Previous), Causing Obstructed Labor
Interventions: PROCEDURE: Physiotherapy|DIAGNOSTIC_TEST: Urogynaecology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Status: COMPLETED
Conditions: Smokeless Tobacco Cessation
Interventions: BEHAVIORAL: #EnufSnuff.TXT Intervention|BEHAVIORAL: Enough Snuff Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Evaluation Study of BVAC-C in Patients With HPV Type 16 or 18 Positive Cervical Cancer
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: BVAC-C|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Superficial Femoral Artery Lesions With FFR From the ACIST Navvus® Catheter
Status: WITHDRAWN
Conditions: Peripheral Arterial Disease|Superficial Femoral Artery Stenosis
Interventions: DEVICE: Fractional Flow Reserve (FFR)|DEVICE: High Definition Intravascular Ultrasound (HD-IVUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relative Bioavailability Study for GSK1278863A
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863A|DRUG: GSK1278863A|DRUG: GSK1278863A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of a Smart-phone Based Medication Adherence Platform to Improve Outcomes in Uncontrolled Non-insulin Dependent Diabetes Among Veterans
Status: COMPLETED
Conditions: Diabetes|Diabete Type 2
Interventions: BEHAVIORAL: Dayamed Arthur a novel intelligent medication adherence platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Quality of Life (QoL) After Liver Surgery
Status: COMPLETED
Conditions: Hepatocarcinoma|Cholangiocarcinoma|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Synchrolevels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Tolerability Study of Avanafil in Russia
Status: COMPLETED
Conditions: Sexual Function and Fertility Disorders NEC-Erectile Dysfunction
Interventions: DRUG: AVANAFIL|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects
Status: COMPLETED
Conditions: Familial Lipoprotein Lipase Deficiency
Interventions: GENETIC: Alipogene Tiparvovec (AMT-011), Human LPL [S447X]|DRUG: mycophenolate mofetil|DRUG: cyclosporine|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperfractionated Intensity-modulated Radiotherapy (IMRT) Versus Conventional Fraction IMRT for Patients With Loco-regionally Recurrent Nasopharyngeal Carcinoma.
Status: UNKNOWN
Conditions: Nasopharyngeal Neoplasms|Mortality|Quality of Life|Complications
Interventions: RADIATION: Hyperfractionated IMRT|RADIATION: Conventional Fraction IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the PK and Safety of BCD-201 and Keytruda® in Patients With Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Non Small Cell Lung Cancer
Interventions: DRUG: BCD-201|DRUG: Keytruda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of and Immune Response to HIV Vaccination Followed by Treatment Interruption in HIV Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MRK Ad5 HIV-1 gag vaccine|OTHER: Vaccine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Previously Treated Myelodysplastic Syndrome|Recurrent Adult Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type II|Diabetes Mellitus, Adult-Onset|Inflammation
Interventions: DRUG: Victoza (liraglutide) with dietician monitoring|OTHER: Placebo with dietician monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ADAPT - Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: BIIB031 (rFVIIIFc)|DRUG: FVIII (PK subgroup only)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between External Oblique Intercostal Plane Block and the Transversus Abdominis Plane Block in Paraumbilical Hernia Repair as Analgesia for Intraoperative and Postoperative Pain.
Status: NOT_YET_RECRUITING
Conditions: Paraumbilical Hernia
Interventions: PROCEDURE: External Oblique Intercostal (EOI) block|PROCEDURE: Transversus abdominis plane (TAP) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
Status: RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: HSV-tk +Valacyclovir in Combination with Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Additional Chemotherapy for EGFRm Patients With the Continued Presence of Plasma ctDNA EGFRm at Week 3 After Start of Osimertinib 1st-line Treatment (PACE-LUNG)
Status: RECRUITING
Conditions: NSCLC Stage IIIB|NSCLC Stage IV
Interventions: DRUG: Osimertinib|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adding Magnesium Sulfate to (Fentanyl/Bupivacaine)Bi-mixture in Caudal Block
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: ultrasound guided caudal epidural block using 1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl|PROCEDURE: ultrasound guided caudal epidural block using 50 mg of Magnesium sulfate added to(1ml/kg of Bupivacaine 0.25% + 0.5microgram/kg of Fentanyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Gamification on Breastfeeding Self-Efficacy and Infant Nutrition Attitudes of Pregnant Women
Status: COMPLETED
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Gamified Breastfeeding Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Somerset and South Essex Coronavirus Antigen Testing
Status: UNKNOWN
Conditions: COVID|SARS-CoV 2
Interventions: DIAGNOSTIC_TEST: PCL COV05 - COVID 19 Ag Rapid FIA test (Rapid Antigen Test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Durvalumab and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Metastatic
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Platinum-Based Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: F511 Cream in Preventing Palmar-Plantar Erythrodysesthesia in Patients Receiving Doxorubicin Hydrochloride Liposome for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Palmar-plantar Erythrodysesthesia
Interventions: DRUG: antiperspirant cream F511|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study in Male Pediatric Patients With Cerebral X-linked Adrenoleukodystrophy (Cald) to Assess the Effects of MIN-102 Treatment on Disease Progression Prior to Human Stem Cell Transplant (HSCT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Adrenoleukodystrophy
Interventions: DRUG: MIN-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Irritation Study of GSK2894512 Cream
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: GSK2894512 Cream|DRUG: Vehicle Cream|DRUG: Empty Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Obstruction Detection by Molecular Personalized Gene Expression (Corus CAD or ASGES)
Status: COMPLETED
Conditions: Coronary Artery Disease|Chest Pain|Cardiovascular Diseases|Coronary Heart Disease|Angina Pectoris|CAD|CVD|CHD
Interventions: DIAGNOSTIC_TEST: Corus CAD (ASGES)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physiological Changes With High-Flow Nasal Cannula
Status: COMPLETED
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: PROCEDURE: High flow nasal cannula|PROCEDURE: Nasal CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study
Status: RECRUITING
Conditions: Sarcoma|Hyperbaric Oxygen Therapy
Interventions: DRUG: Hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: RO6895882
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Rituximab in Treating Patients With Relapsed or Refractory B-cell Lymphoma
Status: COMPLETED
Conditions: CD20 Positive|Recurrent B-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of 5-fluorouracil/Mitomycin for the Patients With Pulmonary Metastasis of Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Lung Metastasis
Interventions: DRUG: 5-fluorouracil|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Ultrasound and Acupuncture to Explore the De-qi Location and Reaction of Specific Acupoints
Status: RECRUITING
Conditions: de qi of Acupuncture|Ultrasound Imaging
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neovascularization Induced by Mechanical Barrier disrUption and Systemic Erythropoietin in Patients With Cerebral Perfusion Deficits
Status: COMPLETED
Conditions: Angiogenesis|Ischemic Stroke
Interventions: DRUG: erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Single Doses Of SBI-087 In Japanese Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: SBI-087|DRUG: SBI-087|DRUG: SBI-087|DRUG: SBI-087
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Attention Training Interventions on Depression
Status: TERMINATED
Conditions: Depression|Attention Training|Symptoms, Cognitive|Symptoms, Affective|Symptoms, Behavioral
Interventions: BEHAVIORAL: attention training intervention 1|BEHAVIORAL: attention training intervention 2|BEHAVIORAL: attention training intervention 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Diabetic Foot Ulcers With Inforatio Technique to Promote Wound Healing
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Diabetic Foot|Wound Heal|Ulcer Foot|Ulcer Healing
Interventions: PROCEDURE: Inforatio technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Treatment of Hepatitis C Virus Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C, Chronic|Opioid Dependence, on Agonist Therapy
Interventions: OTHER: Health care delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Topical Cidofovir for the Prevention of Hair Growth
Status: COMPLETED
Conditions: Prevention of Hair Growth
Interventions: DRUG: 1% topical cidofovir|DRUG: 3% topical cidofovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System
Status: COMPLETED
Conditions: Peripheral Artery Disease|Peripheral Vascular Disease|Vascular Disease|Cardiovascular Diseases|PAD
Interventions: DEVICE: FlexStent® Femoropopliteal Self Expanding Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Under Knee Lower Limb Bypass Types:Endothelialised Prosthesis Versus Autologous Vein Graft
Status: UNKNOWN
Conditions: Arteritis
Interventions: DEVICE: endothelialised prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Myeloma Pack: A Multi-Modality Educational Intervention Strategy to Engage Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: OTHER: ARM A EARLY INTERVENTION GROUP|OTHER: ARM B DELAYED INTERVENTION GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in Bladder
Status: TERMINATED
Conditions: Recurrent Bladder Cancer|Stage III Bladder Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: docetaxel|DRUG: lapatinib ditosylate|OTHER: immunohistochemistry staining method|GENETIC: fluorescence in situ hybridization|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus
Status: COMPLETED
Conditions: Keratoconus|Corneal Crosslinking|Corneal Biomechanics|Corneal Densitometry|Scheimpflug Photography|Corneal Disease|Eye Diseases
Interventions: PROCEDURE: Epi-on PiXL|PROCEDURE: Epi-Off PiXL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea in Pregnancy
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Pregnancy|Obesity, Morbid
Interventions: DEVICE: ApneaLink Air|BEHAVIORAL: Berlin Quesionnaire|BEHAVIORAL: Epworth Sleepiness Scale|BEHAVIORAL: STOP-BANG questionnaire|OTHER: Physical exam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)
Status: NOT_YET_RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: CHW Sessions|DEVICE: WiseApp|DEVICE: CleverCap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fidaxomicin Versus Standard of Care Therapy in Solid Organ Transplant Recipients With Clostridium Difficile Infection
Status: WITHDRAWN
Conditions: Clostridium Difficile Infection|Solid Organ Transplant
Interventions: DRUG: fidaxomicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHP677: I-Metaiodobenzylguanidine (I-MIBG) Therapy for Refractory Neuroblastoma: a Phase II Study
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: 131I-MIBG
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Role of Doppler Endoscopic Probe in the Diagnosis of Subepithelial Gastrointestinal Lesions.
Status: RECRUITING
Conditions: Subepithelial Tumors of the Upper Gastrointestinal Tract
Interventions: DEVICE: Doppler investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Two Techniques to Reposition the Maxilla After le Fort 1
Status: COMPLETED
Conditions: Dentofacial Deformities|Le Fort; I
Interventions: PROCEDURE: Orthognathic surgery (lefort1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hub Cleansing to Prevent Hub Infection
Status: COMPLETED
Conditions: Bacteremia
Interventions: OTHER: 15 second scrub|OTHER: 5 second scrub|DRUG: 3.15% chlorhexidine/70% isopropyl alcohol|DRUG: 70% isopropyl alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: methotrexate|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin and RT With or Without Gemcitabine, Carboplatin, and Paclitaxel in Treating Patients With Locally Advanced NPC
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin,|DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Dendritic Cell-Based Vaccines in Melanoma Patients by Depletion of Regulatory T Cells in Stage IV Melanoma Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Daclizumab|BIOLOGICAL: Dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Validation of Sentinel Lymph Node Biopsy After Neo-adjuvant Chemotherapy in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Sentinel Lymph Node Biopsy|Neoadjuvant Therapy
Interventions: PROCEDURE: SLNB + ALND
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/II Trial to Investigate BI 836858 in Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: PROCEDURE: Best Supportive Care|DRUG: BI 836858
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrogen Peroxide to the Wound Following Surgical Incision Affecting Cultures in Primary Shoulder Arthroplast
Status: COMPLETED
Conditions: Primary Anatomic or Reverse Total Shoulder Arthroplasty
Interventions: OTHER: H2O2 application to incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Versus Micropulse in Central Serous Chorioretinopathy (CSC)
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DEVICE: subthreshold micropulselaser|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Safety Study of Live Attenuated Mumps (F-genotype) Vaccine (Human Diploid Cell, KMB-17) in Chinese Children
Status: COMPLETED
Conditions: Mumps
Interventions: BIOLOGICAL: 3.50±0.25logCCID50/ml|BIOLOGICAL: 4.25±0.25 logCCID50/ml|BIOLOGICAL: 5.00±0.25 logCCID50/ml|BIOLOGICAL: 0 logCCID50/ml|BIOLOGICAL: Attenuated Mumps vaccine (Zhe Jiang Vacn Bio-pharmaceutical Co., LTD.; NO.20110528-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Upper Trapezius Stretching With and Without Mid Lower Trapezius Strengthening in Trapezius Myalgia
Status: COMPLETED
Conditions: Trapezius Myalgia
Interventions: OTHER: upper trapezius stretching plus neck isometrics|OTHER: upper trapezius stretching with mid-lower trapezius strengthening exercises plus neck isometrics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Single and Multiple Dose Study of TAK-137
Status: WITHDRAWN
Conditions: Healthy Japanese Adult Male
Interventions: DRUG: TAK-137 5 mg tablet, TAK-137 placebo tablet|DRUG: TAK-137 5 mg tablet, TAK-137 placebo tablet|DRUG: TAK-137 5 mg tablet, TAK-137 placebo tablet or TAK-137 0.5 mg tablet, TAK-137 placebo tablet|DRUG: TAK-137 5mg tablet, TAK-137 placebo tablet|DRUG: TAK-137 5 mg tablet, TAK-137 placebo tablet|DRUG: TAK-137 5mg tablet, TAK-137 placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Functioning of Children and Adolescents With CHD andTheir Parents, An Intervention Based Study
Status: UNKNOWN
Conditions: Congenital Heart Disease|Psychological Intervention|Parenting|Quality of Life|Psychological Disturbance
Interventions: BEHAVIORAL: problem prevention therapy with CHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in AGHD to Assess Safety, Tolerability and Efficacy of GX-H9
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: GX-H9|DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT