pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: GENETIC: SB-728mR-T|GENETIC: SB-728mR-T|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Intermittent theta burst repetitive transcranial magnetic stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Yellow Fever Inactivated Vaccine
Status: COMPLETED
Conditions: Yellow Fever
Interventions: BIOLOGICAL: XRX-001 Inactivated yellow fever vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Post Operative Loperamide in Colorectal Patients After Diverting Ileostomies
Status: TERMINATED
Conditions: Dehydration, Diverting Ileostomy, Loperamide
Interventions: DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Bioavailability Study of Apixaban Solution Formulation Relative to Apixaban Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Wholegrains on Children's Health (KORN)
Status: COMPLETED
Conditions: Cardiometabolic Health|Gastro-intestinal Wellbeing|Cognitive Function|Overweight
Interventions: DIETARY_SUPPLEMENT: Grain products high in wholegrains from oat and rye|DIETARY_SUPPLEMENT: Grain products low in wholegrains
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)
Status: RECRUITING
Conditions: Neoplasms
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 30 Day Mobile App Programs for Stress Management in Customer Service Representatives
Status: COMPLETED
Conditions: Psychological Stress|Inflammation
Interventions: BEHAVIORAL: Mindfulness Training|BEHAVIORAL: Reflection and Problem Solving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Coronary Revascularization Based on CMR Viability Study Vs Direct Revascularization in Ischemic Cardiomyopathy Patients
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy
Interventions: DEVICE: cardiac MRI|PROCEDURE: Percutaneous coronary intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amelioration of Literacy Deficits in Prenatal Care
Status: COMPLETED
Conditions: Prenatal Care|Health Literacy|Numeracy
Interventions: BEHAVIORAL: Healthy Babies and Healthy Moms|BEHAVIORAL: Baby Basics Prenatal Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Human Immune Globulin in Treating Patients With Primary Amyloidosis That is Causing Heart Dysfunction
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Neoplasm
Interventions: BIOLOGICAL: Human immune globulin intravenous (IGIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antidiabetic Effects on Intrahepatic Fat
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Type2 Diabetes
Interventions: DRUG: Liraglutide|DRUG: Metformin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Carmustine in Treating Patients With Relapsed or Progressive High-Grade Glioma
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: bevacizumab|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of Recombinant Human Granulocyte Colony Stimulating Factor (GCSF)
Status: COMPLETED
Conditions: Chemotherapy-Induced Neutropenia
Interventions: BIOLOGICAL: Recombinant Human GCSF (Shantha Biotechnics Limited)|BIOLOGICAL: Neupogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brain Imaging in Cerebral Venous Outflow Disturbance
Status: RECRUITING
Conditions: Abnormal Cerebral Venous Sinus Morphology|Internal Jugular Vein Stenosis|Image
Interventions: RADIATION: high-resolution 3D-T1|RADIATION: diffusion tensor imaging (DTI)|RADIATION: resting-state functional magnetic resonance imaging (rs-fMRI)|RADIATION: arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI)|RADIATION: susceptibility-weighted images (SWIs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Obstructive Sleep Apnoea and CPAP Treatment Response in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Non-alcoholic Fatty Liver Disease
Interventions: DEVICE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I)
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinomas
Interventions: DRUG: Tislelizumab（neoadjuvant）|DRUG: Cisplatin （neoadjuvant）|DRUG: Nab-paclitaxel （neoadjuvant）|PROCEDURE: Surgical resection|DRUG: Cisplatin（adjuvant）|DRUG: Tislelizumab（adjuvant）|RADIATION: Radiation|DRUG: Carboplatin (neoadjuvant）|DRUG: Carboplatin (adjuvant）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab, Pomalidomide, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Status: WITHDRAWN
Conditions: Recurrent Plasma Cell Myeloma
Interventions: BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Communicating Risks: Consent for Lumbar Puncture
Status: COMPLETED
Conditions: Informed Consent, Health Literacy, Risk, Spinal Puncture, Neurosurgery
Interventions: OTHER: Anatomy diagrams|OTHER: Standard informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quality of Life (QOL) After Elective Sigmoidectomy for Diverticular Diseases (DIVERTI)
Status: UNKNOWN
Conditions: Diverticular Disease of Left Side of Colon
Interventions: PROCEDURE: left elective colectomy (Surgical Experimental Group)|DRUG: antibiotic therapy (medical Control Group)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Healthcare Transition of Adolescents With Chronic Health Conditions
Status: UNKNOWN
Conditions: Transition|Diabetes|Kidney Diseases|Liver Diseases|Inflammatory Bowel Diseases|Rheumatic Diseases|Congenital Heart Disease|Neurologic Disorder
Interventions: BEHAVIORAL: Transition support service
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy
Status: RECRUITING
Conditions: Subacute Cutaneous Lupus Erythematosus|Chronic Cutaneous Lupus Erythematosus
Interventions: DRUG: BIIB059 (litifilimab)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Intravesical Chemotherapy After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Randomized Controlled Trial Between Single Postoperative Dose Versus Maintenance Therapy.
Status: COMPLETED
Conditions: Neoplasm, Ureter|Neoplasm, Bladder
Interventions: DRUG: Immediate instillation of intravesical chemotherapy-Epirubicin-|DRUG: Maintainance therapy of intravesical chemotherapy-Epirubicin-
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
Status: COMPLETED
Conditions: Pulp Necrosis|Regeneration
Interventions: DRUG: Triple Antibiotic Paste|OTHER: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Stem Cell Biomarkers as a Predictor of Response to Trastuzumab in Samples From Patients With Breast Cancer Previously Treated in the NSABP-B-31 Trial
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: fluorescence in situ hybridization|OTHER: immunohistochemistry staining method|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Cycle Ergometer in the Rehabilitation of Elderly Patients With Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Osteonecrosis
Interventions: BEHAVIORAL: Ergometer cycling|BEHAVIORAL: Conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study
Status: WITHDRAWN
Conditions: Neurofibromatosis Type 1|Plexiform Neurofibromas|Post-operative
Interventions: DRUG: Selumetinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromyographic Biofeedback and Physical Therapy in Upper Limb Hemiparesis
Status: COMPLETED
Conditions: Electromyography
Interventions: PROCEDURE: Biofeedback Electromyography|PROCEDURE: Sham Biofeedback Electromyography|PROCEDURE: Conventional Physical Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MEGA (Met or EGFR Inhibition in Gastroesophageal Adenocarcinoma): FOLFOX Alone or in Combination With AMG 102 or Panitumumab as First-line Treatment in Patients With Advanced Gastroesophageal Adenocarcinoma
Status: COMPLETED
Conditions: Malignant Neoplasm of Esophagus|Malignant Neoplasm of Stomach
Interventions: DRUG: Oxaliplatin|DRUG: Folinic Acid|DRUG: 5-fluoro-uracil|DRUG: panitumumab|DRUG: AMG102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)
Status: SUSPENDED
Conditions: Heart Failure|Chronic Systolic Heart Failure|Renal Failure|Cardiorenal Syndrome
Interventions: DEVICE: Selective Cytopheretic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Immunoglobulin (Hizentra) in Patients With Dermatomyositis: A Proof of Concept Study
Status: TERMINATED
Conditions: Dermatomyositis
Interventions: DRUG: Immunoglobulin (Hizentra)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Epirubicin as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Adenocarcinoma of the Stomach
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: docetaxel|DRUG: epirubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Lung Protective Ventilation Strategies and Tumor Microenvironment
Status: ENROLLING_BY_INVITATION
Conditions: Tumor Microenvironment
Interventions: PROCEDURE: Lung protective ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Urinary and Sexual Functions After Subtotal Versus Total Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Sexual Function Disturbances|Urinary Function Disorders
Interventions: PROCEDURE: subtotal hystrectomy|PROCEDURE: Total hystrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Cetuximab and Bevacizumab in Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma
Interventions: DRUG: Cetuximab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anthocyanin Intake From Purple Sweet Potato in Cerebral Small Vessel Disease
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: OTHER: The water extract of "Biang" variety purple sweet potato
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of N-Acetylcysteine on Morbidity, Oxygenation and Cytokine Levels in Partial or Total Esophagectomy for Cancer
Status: COMPLETED
Conditions: Pulmonary Morbidity
Interventions: DRUG: n-acetylcysteine|DRUG: 250mL glucose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of EBUS TBNA for Cell Culture as an Aid to Diagnose Lung Cancer and Lymphoma
Status: COMPLETED
Conditions: Lung Cancer|Lymphoma|Non-small Cell Lung Cancer|Non-Hodgkin Lymphoma|Mediastinal Lymphadenopathy
Interventions: OTHER: Cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adjunctive Benefit of a Xenogenic Collagen Matrix
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF+XCM|PROCEDURE: CAF alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?
Status: COMPLETED
Conditions: Sport-related Concussion|Brain Concussion|Healthy
Interventions: OTHER: high-intensity neck strengthening|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VR to Evaluate Phantom Limb Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Phantom Limb Pain|Phantom Pain|Phantom Sensation|Phantom Limb Syndrome With Pain|Phantom Pain Following Amputation of Lower Limb|Phantom Pain Following Amputation of Upper Limb|Amputation|Upper Limb Amputation at the Hand|Upper Limb Amputation at the Wrist|Upper Limb Amputation Below Elbow (Injury)|Upper Limb Amputation Above Elbow (Injury)|Lower Limb Amputation Knee|Lower Limb Amputation Above Knee (Injury)|Lower Limb Amputation Below Knee (Injury)|Lower Limb Amputation at Ankle (Injury)
Interventions: DEVICE: Coapt Phantom Limb Pain Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: 6-Month Extension Trial of Asenapine With Olanzapine in Negative Symptoms Patients Who Completed the First 6- Month Trial (A7501014)(COMPLETED)(P05772)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: asenapine|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platform Trial to Compare Homologous Boost of Authorized COVID-19 Vaccines and Heterologous Boost With UB-612 Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Vaccines
Interventions: BIOLOGICAL: UB-612|BIOLOGICAL: BNT162b2 vaccine|BIOLOGICAL: ChAdOx1-S vaccine|BIOLOGICAL: Sinopharm BIBP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: PROCEDURE: Punctal plugs, punctal cautery|PROCEDURE: Punctal Plug, Punctal thermocauterization|PROCEDURE: Silicone plug or thermodynamic hydrophobic acrylic plug|OTHER: Previous subjects with Punctal occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents
Status: COMPLETED
Conditions: Gingival Inflammation
Interventions: DRUG: freeze-dried probiotic sachets|DIETARY_SUPPLEMENT: fermented dairy product ( yogurt)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pink Esthetic Score Around Immediate Implants Using PDDM as Jumping Gap Filling Material.
Status: NOT_YET_RECRUITING
Conditions: Prostheses|Endosseous Dental Implant Failure
Interventions: PROCEDURE: Immediate implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Warm Water Sitz Bath on Urinary Retention After Hemorrhoidectomy
Status: COMPLETED
Conditions: Hemorrhoids|Haemorrhoids|Piles|Hemorrhoidal Disease
Interventions: OTHER: early warm water sitz bath|OTHER: Regular time warm water sitz bath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Placebo Controlled Study of Preladenant in Participants With Moderate to Severe Parkinson's Disease (P07037)
Status: COMPLETED
Conditions: Parkinson Disease|Idiopathic Parkinson Disease|Idiopathic Parkinson's Disease
Interventions: DRUG: Preladenant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Awake Fiberoptic And Awake Video Laryngoscopy Tracheal Intubation in Cervical Surgery
Status: UNKNOWN
Conditions: Cervical Disorder
Interventions: DEVICE: AWAKEN INTUBATION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women
Status: COMPLETED
Conditions: Labor Pain
Interventions: DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cyclobenzaprine HCl Extended Release 15 mg Versus Placebo in Treatment of Cervical and/or Lower Back Pain Due to Muscle Spasms of Local Origin
Status: COMPLETED
Conditions: Neck Pain|Back Pain|Spasm
Interventions: DRUG: Cyclobenzaprine HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Pharmacotherapy for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Varenicline Standard Protocol|BEHAVIORAL: Nicotine Patch Standard Protocol|DRUG: Varenicline Adaptive Protocol|DRUG: Nicotine Adaptive Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide Versus Placebo for GJ Placement
Status: COMPLETED
Conditions: Radiation Exposure|Enteral Nutrition
Interventions: DRUG: Metoclopramide 5 MG/ML Injectable Solution|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: CHOP regimen|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: idarubicin|DRUG: ifosfamide|DRUG: mesna|DRUG: methylprednisolone|DRUG: mitoxantrone hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Pacing for AV Block to Prevent Pacemaker-induced Cardiomyopathy
Status: RECRUITING
Conditions: Conduction System Pacing|Conventional Ventricular Pacing
Interventions: DEVICE: Pacemaker implantation and conventional cardiac pacing|DEVICE: Conduction system pacing implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pradefovir Treatment for the Patients With Chronic Hepatitis B Virus Infections: a Phase3 Study
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: Pradefovir Mesylate;Placebo of Tenofovir disoproxil fumarate tablet|DRUG: Tenofovir disoproxil fumarate tablet;Placebo of Pradefovir Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Zimberelimab(GLS-010) Combined With AVD for Newly Diagnosed Early-stage Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Zimberelimab 240mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An 8 Week Open-Label Study to Evaluate the Efficacy and Safety of Acamprosate Calcium (Campral) as Augmentation Therapy in Patients With Anxiety Symptoms Who Are Only Partial Responders to SSRI or SNRI Antidepressants
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Acamprosate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Cognitive Impairment in Glioma With Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training
Status: NOT_YET_RECRUITING
Conditions: Cognitive Impairment|Glioma
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|BEHAVIORAL: cognitive strategy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Safety, Efficacy and Tolerability of CKD-519, Administered With HMG-CoA Reductase Inhibitors
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Atorvastatin 20mg|DRUG: Atorvastatin 20 mg + CKD-519 50 mg|DRUG: Atorvastatin 20 mg + CKD-519 100 mg|DRUG: Atorvastatin 20 mg + CKD-519 200 mg|DRUG: Rosuvastatin 10 mg|DRUG: Rosuvastatin 10 mg + CKD-519 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and Angina
Status: COMPLETED
Conditions: Heart Failure|Myocardial Ischemia|Angina Pectoris
Interventions: DRUG: CK-1827452 24mg and 6 mg iv infusion|DRUG: CK-1827452 12.5mg capsule|DRUG: CK-1827452 48 mg and 11 mg iv infusion|DRUG: CK-1827452 25mg capsule|DRUG: Placebo iv infusion|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2a Study to Evaluate FL-301 in Patients With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Pancreas Cancer|Gastric Cancer|Solid Tumor
Interventions: DRUG: 1 mg/kg IV FL-301|DRUG: 3 mg/kg IV FL-301|DRUG: 10 mg/kg IV FL-301|DRUG: 20 mg/kg IV FL-301|DRUG: 30 mg/kg IV FL-301|DRUG: RP2D, IV FL-301|DRUG: RP2D, IV FL-301|DRUG: RP2D, IV FL-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT-guided Pudendal Nerve Cryoneurolysis for Palliation of Malignancy-induced Pelvic Pain
Status: NOT_YET_RECRUITING
Conditions: Malignancy-induced Pelvic Pain
Interventions: DRUG: CT-guided Pudendal Nerve Cryoneurolysis|DRUG: Percutaneous image-guided cryoneurolysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Seroquel for Frequent, Heavy Drinkers
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Seroquel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML
Status: RECRUITING
Conditions: Adult Acute Myeloid Leukemia
Interventions: BIOLOGICAL: microtransplantation, HLA-mismatched donor peripheral stem cell infusion|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plaque Psoriasis Study in Pediatric Subjects
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: calcitriol ointment|DRUG: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative|Gastrointestinal Diseases|Pathologic Processes|Intestinal Diseases|Inflammatory Bowel Diseases
Interventions: DEVICE: AutoRIC device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Effects of Herbst Appliance in Skeletal Class II Cases During Prepubertal and Postpubertal Periods
Status: COMPLETED
Conditions: Class II Malocclusion, Division 1
Interventions: DEVICE: Herbst appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITEIIIB)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Age-related Macular Degeneration
Interventions: DEVICE: Valeda Light Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ibrutinib Plus Venetoclax Plus Obinutuzumab in Patients With CLL
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic
Interventions: DRUG: ibrutinib|DRUG: obinutuzumab|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multifocal HD-tDCS and Motor Function
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Standard HD-tDCS intervention|DEVICE: Multifocal network targeted HD-tDCS intervention|DEVICE: Functional Magnetic Resonance Imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence
Status: RECRUITING
Conditions: Colorectal Cancer|Polyp of Colon
Interventions: PROCEDURE: Hybrid Argon Plasma Coagulation and EMR procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
Status: RECRUITING
Conditions: Rotator Cuff Injuries
Interventions: DEVICE: Isolated Bioinductive Repair|PROCEDURE: Completion and Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Potential for Orthostatic Hypotension in Elderly Hypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Carvedilol CR capsules|DRUG: Placebo|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Recurrent Prostate Carcinoma
Interventions: DRUG: Abiraterone Acetate|DRUG: Bicalutamide|DRUG: Degarelix|DRUG: Flutamide|DRUG: Goserelin Acetate|DRUG: Leuprolide Acetate|DRUG: Nilutamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC)
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer|Gastrointestinal Cancer|Gynecologic Cancer|Thoracic Cancer|Genitourinary Cancer
Interventions: OTHER: Clinician Nudge Email|OTHER: Patient Nudge Letter and Share questionaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms
Status: COMPLETED
Conditions: Breast Cancer|Cognitive Symptoms|Cognitive Decline
Interventions: OTHER: Written information about potential chemotherapy-related cognitive symptoms without self-affirmation|OTHER: Written information about potential chemotherapy-related cognitive symptoms with self-affirmation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)
Status: COMPLETED
Conditions: Urethritis
Interventions: DRUG: Tinidazole|OTHER: Placebo|DRUG: Doxycycline|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Flexible-Dose Titration Study of Aptensio XR in Children Ages 4 to Under 6 Years Diagnosed With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Aptensio XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression
Status: NOT_YET_RECRUITING
Conditions: Treatment Resistant Depression|Inflammation|Overweight
Interventions: DRUG: Omega 3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib (Tarceva) Versus Gemcitabine/Cisplatin as First-line Treatment in Patients With Non-small Cell Lung Cancer With EGFR Mutations
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil
Status: COMPLETED
Conditions: Tuberculosis
Interventions: OTHER: Xpert MTB/Rif|OTHER: Smear microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of ACT-128800 in Patients With Relapsing-remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: ACT-128800 Dose 1|DRUG: Placebo|DRUG: ACT-128800 Dose 2|DRUG: ACT-128800 Dose 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apixaban for the Prevention of Venous Thromboembolism in Cancer Patients
Status: COMPLETED
Conditions: Venous Thromboembolism|Cancer
Interventions: DRUG: Apixaban|DRUG: Placebo drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Asthma Education Given by Taking Health Literacy Into Account
Status: COMPLETED
Conditions: Asthma in Children|Health Literacy|Child Health|Asthma Management|Nursing
Interventions: OTHER: Asthma Education|OTHER: Delivery of booklets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis
Status: COMPLETED
Conditions: HIV-1 Infection|Tuberculosis
Interventions: DRUG: Tenofovir + lamivudine + raltegravir|DRUG: Tenofovir + lamivudine + efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying the Pathways and Resources for Engagement and Participation Protocol Among People With Muscles Dystrophies
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy
Interventions: BEHAVIORAL: Pathways and Resources for Engagement and Participation (PREP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Double vs Standard Empapagliflozin Dose for METabolic syndromE tReatment
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Empagliflozin 20 mg|DRUG: Empagliflozin 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics After Administration of BR3003 and Co-administration of BR3003B and BR3003C.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BR3003(T)|DRUG: BR3003B(R1)|DRUG: BR3003C(R2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants
Status: RECRUITING
Conditions: Prematurity|Iron-deficiency|Iron Deficiency Anemia|Iron Malabsorption
Interventions: DRUG: Darbepoetin Alfa|DRUG: Low Molecular Weight Iron Dextran|DRUG: Ferumoxytol injection|DRUG: Oral iron supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Eszopiclone Compared to Placebo on Daytime Function in Subjects With Insomnia Related to Rheumatoid Arthritis
Status: COMPLETED
Conditions: Insomnia|Arthritis, Rheumatoid
Interventions: DRUG: Eszopiclone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tamsulosin Phase III Clinical Trial -Double-Blind, Placebo Controlled Study in Female Patients With Lower Urinary Tract Syndrome
Status: COMPLETED
Conditions: Urinary Tract Diseases
Interventions: DRUG: Tamuslosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: ARBITER-II: Aorfix™ Bifurcated Safety and Performance Trial: Phase II, Angulated Vessels
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Aorfix™ Stent Grafts (AAA endovascular procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Standard Nutrition Therapy on Nutritional Status and Prognosis in Locoregionally Advanced Nasopharyngeal Carcinoma Patients With Malnutrition
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nutrition Therapy
Interventions: OTHER: Standardized nutrition therapy|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Aided Gap Balancing Improves Sagittal Stability and Outcomes for Cruciate-Retaining Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: PROCEDURE: Computer aided total knee arthroplasty|PROCEDURE: Conventional total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Octagam (Intravenous Immunoglobulin [IVIG]) 10% on the Treatment of Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo|BIOLOGICAL: octagam 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Probiotics in IBS Subjects
Status: COMPLETED
Conditions: IBS
Interventions: DIETARY_SUPPLEMENT: Probiotic 1|DIETARY_SUPPLEMENT: Probiotic 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1b-2 Trial to Assess Venetoclax and Navitoclax Consolidation and Post-transplant Maintenance in High-risk Patients With T-ALL
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Navitoclax|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Fat as a Dietary Target for Treating Cardiometabolic Disorders in Prediabetes and Type 2 Diabetes
Status: COMPLETED
Conditions: NAFLD|Diabetes Mellitus, Type 2|PreDiabetes
Interventions: OTHER: Customized diet to reduce liver fat|OTHER: Healthy Nordic diet|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Modified Tracheo-Esophageal Voice Prosthesis for Total Laryngectomy Patients
Status: UNKNOWN
Conditions: Laryngeal Cancer|Hypopharynx Cancer
Interventions: DEVICE: Modified Trans-Esophageal Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pterygomaxillary Disjunction With Interpositional Y-shape Plate in Patients With Temporomandibular Joint Derangement
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: PROCEDURE: Pterygomaxillary disjunction with interposition Y-shape plate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevena™ Incision Management System Over Primarily Closed Hip and Knee Incisions in Patients Immediately Post Total Hip and Knee Arthroplasty
Status: WITHDRAWN
Conditions: Linear or Emi-linear Incisions|Total Hip Arthroplasty|Total Knee Arthroplasty
Interventions: DEVICE: Prevena Incisional Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High vs. Moderate Protein Consumption on Human Health
Status: COMPLETED
Conditions: Weight Loss|Metabolism and Nutrition Disorder|Obesity
Interventions: DIETARY_SUPPLEMENT: VLCD-Active|OTHER: Maintenance-Active|DIETARY_SUPPLEMENT: VLCD-Control|OTHER: Maintenance-Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Exercises Plan With or Without Laser Guided Feedback for Patients With Non-Specific Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: DIAGNOSTIC_TEST: Low-level laser therapy (LLLT) or cold laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation
Status: RECRUITING
Conditions: Diabetic Foot|Gangrene; Limb|Wound Infection|Wound Healing Delayed|Wound Complication|Critical Limb-Threatening Ischaemia|Amputation
Interventions: PROCEDURE: Bone Saw|PROCEDURE: Bone Cutter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Lumbar plexus block|PROCEDURE: Quadratus lumborum type 3 block|DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Open-Label, Comparative, Parallel-Group, Multicenter Study of SPARC1507
Status: WITHDRAWN
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: SPARC1507|DRUG: Reference1507
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma
Status: UNKNOWN
Conditions: Breast Cancer|Endometrial Cancer|Malignant Mesothelioma
Interventions: DRUG: megestrol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cross Over Convenience And Preference Study Of New Mark VII Compared To Genotropin Pen In Pediatric And Adult Subjects
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DEVICE: Genotropin Pen|DEVICE: MARK VII pen|DEVICE: Genotropin Pen|DEVICE: MARK VII pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant
Status: RECRUITING
Conditions: Familial Alcoholism Vulnerability
Interventions: DRUG: Mavoglurant (AFQ056)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VST-1001 (Dilute Fluorescein) for Lymphatic Mapping & Localization of Lymph Nodes in Patients With Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: VST-1001|DRUG: 99mTc-labeled sulfur colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Diabetes Mellitus|Coronary Disease
Interventions: DRUG: Empagliflozin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT