pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Anabolic Properties of a Lipid-rich Pork Matrix
Status: RECRUITING
Conditions: Muscle Protein Synthesis
Interventions: OTHER: 95.1% Lean Pork|OTHER: 81.16% Lean Pork|OTHER: Carbohydrate Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis
Status: RECRUITING
Conditions: Mastitis|Breast Milk|Lactation|Women's Health|Infant Health
Interventions: DIETARY_SUPPLEMENT: Lactobacillus fermentum CECT5716|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile Medication Adherence Platform for Buprenorphine-Naloxone During Treatment of Opioid Use Disorder: Phase I Study
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Reminders messages to improve adherence.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study of Prophylactic Agent for Venous Thromboembolism After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: acetylsalicylic acid|DRUG: rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Real World Study Evaluating the Long-Term Quality of Life of Tildrakizumab in Adult Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Injections of tildrakizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music-visual Guided Physical Activity Promotion for Adults With Intellectual Disabilities
Status: UNKNOWN
Conditions: Intellectual Disability
Interventions: BEHAVIORAL: Music-visual guided physical activity (MVgPA)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Deep Learning Diagnostic and Risk-stratification for IPF and COPD
Status: RECRUITING
Conditions: Lung; Disease, Interstitial, With Fibrosis|Pulmonary Disease, Chronic Obstructive|Artificial Intelligence
Interventions: DEVICE: Lung auscultation|DEVICE: Lung ultrasound|OTHER: Quality of Life's questionnaires|DIAGNOSTIC_TEST: Pulmonary functional tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of VELCADE With Fludarabine in Comparison to Rituximab With Fludarabine in Follicular Lymphoma Patients Previously Treated With Rituximab
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: DRUG: fludarabine|DRUG: rituximab|DRUG: VELCADE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Colorectal Carcinoma|Pancreatic Adenocarcinoma|Breast Cancer|Other Solid Tumors|Ovarian Cancer
Interventions: BIOLOGICAL: Autologous, engineered T Cells targeting TP53 R175H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C-Spine Movement - Shikani Optical Scope vs Macintosh Laryngoscope for Patients With Cervical Spine Injury
Status: COMPLETED
Conditions: Wounds and Injuries
Interventions: DEVICE: Shikani Optical Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)
Status: SUSPENDED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: 0.075 mg RVX-100|DRUG: 0.125 mg RVX-100|DRUG: 0.250 mg RVX-100|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Flexor Hallucis Longus Tears, Associated Os Trigonum Excision, and Return to Play
Status: UNKNOWN
Conditions: Ankle Impingement|Tendon Tear
Interventions: OTHER: Foot Exam Follow-Up|RADIATION: X-ray|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Larynx|Squamous Cell Carcinoma of the Oropharynx|Squamous Cell Carcinoma of the Oral Cavity
Interventions: RADIATION: Hypofractionated Postoperative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: PEG-P-INF alpha-2b (P1101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal Cancer
Status: UNKNOWN
Conditions: Locally Advanced Rectal Cancer
Interventions: DIAGNOSTIC_TEST: Blood concentration check
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood (UCB) Transplant, Fludarabine, Melphalan, and Anti-thymocyte Globulin (ATG) in Treating Patients With Hematologic Cancer
Status: TERMINATED
Conditions: Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: fludarabine phosphate|DRUG: Melphalan|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: umbilical cord blood transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: CR845|DRUG: CR845|DRUG: CR845|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determinants of Age Related Breathing Instability During Non-Rapid-Eye-Movement (NREM) Sleep
Status: COMPLETED
Conditions: Sleep Apnea|Age
Interventions: OTHER: 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SB-715992 in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Docetaxel or Paclitaxel
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: ispinesib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training in Fever Case Management With Rapid Diagnostic Tests (RDTs) for Malaria in Uganda
Status: COMPLETED
Conditions: Malaria|Fever
Interventions: DEVICE: training in use of rapid diagnostic tests (RDTs) for malaria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Strategies to Treat Osteoporosis Following a Fragility Fracture
Status: COMPLETED
Conditions: Osteoporosis|Fractures
Interventions: BEHAVIORAL: Control group|BEHAVIORAL: Minimal Intervention|BEHAVIORAL: Intensive Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Whole-task Hybrid Simulation Improves Medical Student Competence in Cardiology Clerkship
Status: COMPLETED
Conditions: Valvular Heart Disease
Interventions: OTHER: Tuition from a expert clinical trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Liposomal Irinotecan Based FOLFIRI With Bevacizumab in First-line Treatment of Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI+Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoid Leukemia|Philadelphia Chromosome-Negative B-Cell Precursor
Interventions: DRUG: Chemotherapy + Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or Gefitinib
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBW 2992|DRUG: Sirolimus (rapamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PARTNER 3 Trial - Aortic Valve-in-Valve
Status: RECRUITING
Conditions: Aortic Stenosis|Aortic Stenosis, Severe
Interventions: DEVICE: Edwards SAPIEN 3/SAPIEN 3 Ultra THV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Evening Primrose Oil for the Treatment of Breastfeeding Pain
Status: UNKNOWN
Conditions: Breast Feeding
Interventions: DIETARY_SUPPLEMENT: Evening Primrose Oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DiaCon Dual-Hormone Closed-Loop Glucose Control
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: DiaCon dual-hormone closed-loop glucose control algorithm|DEVICE: DiaCon single-hormone closed-loop glucose control algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of Anlotinib in Hepatocellular Carcinoma (HCC) Patients at High Risk of Post Surgery Recurrence
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Motivating Videos to Encourage Cycling for Geriatric Rehabilitation
Status: COMPLETED
Conditions: Physical Activity|Aging|Geriatrics
Interventions: DEVICE: TheraTrainer + Motiview|DEVICE: TheraTrainer Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment
Status: COMPLETED
Conditions: Atherosclerosis|Adherence, Medication|Tolerance
Interventions: DRUG: Polycap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ultrasound-Guided Erector Spinae Block on Respiratory Function After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy|Postoperative Pain|Respiratory Function
Interventions: PROCEDURE: Bilateral Erector Spinae Block|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin
Status: COMPLETED
Conditions: Cocaine Abuse
Interventions: DRUG: Lorcaserin|DRUG: Placebo|DRUG: Cocaine Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-hypertensive Effect of Mycelia of Antrodia Cinnamomea
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: AC mycelia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biological Effects of Treatment With Resveratrol in ART Patients
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tegafur-Uracil or Observation in Treating Patients With Stage II Colorectal Cancer That Has Been Completely Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: UFT adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Impact of Whole Body Cryostimulation on Skin Physiological Indicators
Status: COMPLETED
Conditions: Quality of Life|Atopic Dermatitis
Interventions: OTHER: whole body cryostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CIFeR - A Clinician-led Intervention to Address Fear of Cancer Recurrence
Status: RECRUITING
Conditions: Fear of Cancer Recurrence
Interventions: OTHER: Clinician-led intervention to address fear of cancer recurrence (CIFeR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Integrated Genetic and Functional Analysis of the Influence of Menstrual Hygiene Products on Female Health
Status: RECRUITING
Conditions: Vaginal Disease|Menstrual Discomfort
Interventions: OTHER: Menstrual hygiene products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gene Expression During Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Choline Magnesium Trisalicylate
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: choline magnesium trisalicylate|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inetetamab Combined With Paclitaxel With/Without Pertuzumab for Previously Treated HER2-positive Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Stage IV
Interventions: DRUG: Inetetamab and Paclitaxel ± Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate AXR-159 Ophthalmic Solution in Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: AXR-159|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Wine Effects Upon Gut Flora and Plasma Levels of Trimethylamine-N-oxide (TMAO) - WineFlora Study
Status: COMPLETED
Conditions: Trimethylamine-N-oxide|Gut Microbiota|Effects of Red Wine|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Red Wine consumption|OTHER: Period without alcohol consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer
Status: UNKNOWN
Conditions: Colon Cancer|Locally Advanced Malignant Neoplasm
Interventions: OTHER: Perioperative simplified FOLFOX-4 chemotherapy|OTHER: Perioperative FOLFOX4+Cetuximab chemotherapy|OTHER: Surgery followed by FOLFOX4 chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Blood Levels of Fatty Acids After Consuming Two Forms of Cod Liver Oil
Status: COMPLETED
Conditions: Growth and Development
Interventions: OTHER: Emulsified cod liver oil product|OTHER: Non-emulsified cod liver oil product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Integrated Cancer Repository for Cancer Research
Status: RECRUITING
Conditions: Pancreatic Cancer|Thyroid Cancer|Lung Cancer|Esophageal Cancer|Thymus Cancer|Colon Cancer|Rectal Cancer|Gastrointestinal Stromal Tumors|Anal Cancer|Bile Duct Cancer|Duodenal Cancer|Gallbladder Cancer|Gastric Cancer|Liver Cancer|Small Intestine Cancer|Peritoneal Surface Malignancies|Familial Adenomatous Polyposis|Lynch Syndrome|Bladder Cancer|Kidney Cancer|Penile Cancer|Prostate Cancer|Testicular Cancer|Ureter Cancer|Urethral Cancer|Hypopharyngeal Cancer|Laryngeal Cancer|Lip Cancer|Oral Cavity Cancer|Nasopharyngeal Cancer|Oropharyngeal Cancer|Paranasal Sinus Cancer|Nasal Cavity Cancer|Salivary Gland Cancer|Skin Cancer|Central Nervous System Tumor|Central Nervous System Cancer|Mesothelioma|Breast Cancer|Leukemia|Melanoma|Sarcoma|Unknown Primary Tumor|Multiple Myeloma|Ovarian Cancer|Endometrial Cancer|Vaginal Cancer|Neuroendocrine Tumors|Plasma Cell Dyscrasia|Healthy Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alendronate Treatment of Osteoporosis in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoporosis
Interventions: DRUG: Placebo|DRUG: Alendronate|DRUG: Calcium|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic Exercise on Lower Urinary System Symptoms in Women With Diabetes Mellitus
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Diabetes Mellitus, Type 2
Interventions: OTHER: Aerobic Exercise|BEHAVIORAL: Behavioral Treatment Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety And Efficacy Of Maintenance Therapy With CP-690,550
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Placebo|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open and Comparative Study to Measure Tolerability and Efficacy of Taro Elixir
Status: UNKNOWN
Conditions: Acne Vulgaris II or III Degree|Boils
Interventions: DRUG: oxytetracycline, taro elixir|DRUG: Taro Elixir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of ICSI Using Cryopreserved Testicular Sperm From Infertile Men With Varicocele-associated Azoospermia
Status: UNKNOWN
Conditions: ICSI AZOOSPERMIA VARICOCELE
Interventions: PROCEDURE: ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Status: COMPLETED
Conditions: Advanced Solid Tumors With an Alteration of the PIK3CA Gene|Estrogen Receptor Positive Breast Cancer
Interventions: DRUG: BYL719|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia
Status: UNKNOWN
Conditions: Azoospermia
Interventions: PROCEDURE: Bone marrow stem cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Viaskin Peanut in Children With Immunoglobulin E (IgE)-Mediated Peanut Allergy
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Viaskin Peanut 250mcg|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts
Status: RECRUITING
Conditions: Heart Failure, Congestive
Interventions: DRUG: Furosemide|DRUG: Torsemide|DRUG: Bumetanide|DRUG: sacubitril/valsartan|DRUG: Hydralazine|DRUG: Isosorbide Dinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Alloantigen Reactive Tregs (darTregs) for Calcineurin Inhibitor (CNI) Reduction
Status: COMPLETED
Conditions: Liver Transplant Recipient|Living Donor (of the Respective Liver Transplant Recipient)
Interventions: BIOLOGICAL: darTregs|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Immunosuppression (IS) Withdrawal|PROCEDURE: Study Mandated Procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel in Combination With Pyrotinib in Postoperative Adjuvant Therapy for HER2-positive Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Early Breast Cancer
Interventions: DRUG: Nab-paclitaxel in combination with pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Irinotecan Liposome Injection, Oxaliplatin, 5-fluorouracil/Levoleucovorin in Japanese Participants Not Previously Treated for Metastatic Adenocarcinoma of the Pancreas
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Adenocarcinoma of the Pancreas
Interventions: DRUG: Irinotecan liposome injection (S095013)|DRUG: Oxaliplatin|DRUG: LLV (levoisomer form of leucovorin)|DRUG: 5- FU (5-Fluorouracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SyB P-1501 (Fentanyl HCI) for Treatment of Postoperative Pain
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: SyB P-1501|DRUG: SyB P-1501 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes
Status: UNKNOWN
Conditions: Fetal Distress|Birth Asphyxia
Interventions: DRUG: 100% Oxygen|DRUG: 21% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorafenib Tosylate With or Without Everolimus in Treating Patients With Localized, Unresectable, or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: everolimus|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: BEHAVIORAL: HIIT combined with resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting ER-Golgi Homeostasis in an Advantageous Therapeutic Strategy in Lung Cancer
Status: UNKNOWN
Conditions: The Combined Effect of Hsp90 Inhibitor and HDAC/Proteasome Inhibitors on Lung Cancer Cell Fate and ER-Golgi Homeostasis Will be Examined.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Acute Traumatic Laceration of the Olecranon and Prepatellar Bursa
Status: UNKNOWN
Conditions: Traumatic Laceration of the Olecranon or Prepatellar Bursa
Interventions: PROCEDURE: Bursectomy|PROCEDURE: Bursal reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin for Fatigue and Other Symptoms in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Cancer|Fatigue
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder
Status: COMPLETED
Conditions: Neurogenic Bladder Due to Spina Bifida (Disorder)
Interventions: PROCEDURE: Single-use catheter|PROCEDURE: Reused catheter|DIAGNOSTIC_TEST: Urine culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin Dialysis in End-Stage Renal Disease: Detoxification Capacity and Impact on Vascular Endothelial Function
Status: SUSPENDED
Conditions: Chronic Kidney Disease
Interventions: DEVICE: Fractionated Plasma Separation and Adsorption (FPSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome
Status: RECRUITING
Conditions: Williams Syndrome|Child|Neurodevelopmental Delay
Interventions: DRUG: Clemastine Fumarate Tablets|DIETARY_SUPPLEMENT: fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Therapeutic Air Mixture and Electrical Stimulation to Improve Breathing and Hand Function in Spinal Cord Injury
Status: RECRUITING
Conditions: Cervical Spinal Cord Injury
Interventions: OTHER: Acute Intermittent Hypercapnic Hypoxia|OTHER: Transcutaneous spinal cord stimulation|OTHER: SHAM Acute Intermittent Hypercapnic Hypoxia|OTHER: SHAM Transcutaneous spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: NSCLC
Interventions: DRUG: BPI-7711|DRUG: Gefitinib|DRUG: Placebo Tablet|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between MPV,PDW,PFT and ST Segment Resolution in STEMI Patients Treated With Thrombolytic or Primary PCI
Status: WITHDRAWN
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DRUG: Thrombolytic|PROCEDURE: Primary PCI|DIAGNOSTIC_TEST: Complete blood count|DIAGNOSTIC_TEST: Platelet function test|DIAGNOSTIC_TEST: ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Aroplatin (Liposomal NDDP, L-NDDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dairy on Vitamin K-status
Status: COMPLETED
Conditions: Vitamin K-status|Vascular Health
Interventions: DIETARY_SUPPLEMENT: nutrient enriched product|DIETARY_SUPPLEMENT: basic dairy product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: AT-527 550 mg + cyclosporine|DRUG: AT-527 550 mg + cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces
Status: UNKNOWN
Conditions: Malocclusion|Malocclusion, Angle's Class
Interventions: DEVICE: 3D printed ceramic bracket and tray|DEVICE: Stock ceramic bracket + 3D printed tray|DEVICE: Stock bracket, no tray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Diet Before Sleeve Gastrectomy
Status: COMPLETED
Conditions: Pain
Interventions: DIETARY_SUPPLEMENT: Regular diet|DIETARY_SUPPLEMENT: High protein formula|DIETARY_SUPPLEMENT: Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: EFB0027 (metformin delayed release)|DRUG: EFB0026 (metformin immediate-release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia
Status: COMPLETED
Conditions: Liver Cirrhosis, Biliary
Interventions: COMBINATION_PRODUCT: Autologous BMMC transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Serratus Plane Block on the Respiratory Pattern in Patients With Multiple Rib Fractures
Status: NOT_YET_RECRUITING
Conditions: Rib Fractures|Spirometry
Interventions: PROCEDURE: Serratus plane block (continuous or single-shot)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hypofractionated Radiotherapy Alone in Locally Advanced Nonsmall Cell Lung Cancer Patients
Status: TERMINATED
Conditions: Nonsmall Cell Lung Cancer, Stage II|Nonsmall Cell Lung Cancer Stage III
Interventions: DRUG: Hypofractionated Radiation Therapy|RADIATION: Radiation Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3532226 in Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY3532226|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypokalemia and Intravenous Patient Controlled Analgesia
Status: COMPLETED
Conditions: General Anesthesia|Laparoscopic Cholecystectomy
Interventions: DRUG: IV-PCA|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma
Status: COMPLETED
Conditions: Acoustic Schwannoma|Adult Anaplastic (Malignant) Meningioma|Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Brain Stem Glioma|Adult Choroid Plexus Neoplasm|Adult Craniopharyngioma|Adult Diffuse Astrocytoma|Adult Ependymoblastoma|Adult Ependymoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Grade I Meningioma|Adult Grade II Meningioma|Adult Medulloblastoma|Adult Mixed Glioma|Adult Myxopapillary Ependymoma|Adult Oligodendroglioma|Adult Papillary Meningioma|Adult Pilocytic Astrocytoma|Adult Pineal Gland Astrocytoma|Adult Pineoblastoma|Adult Pineocytoma|Adult Primary Melanocytic Lesion of Meninges|Adult Subependymal Giant Cell Astrocytoma|Adult Subependymoma|Adult Supratentorial Primitive Neuroectodermal Tumor|Malignant Adult Intracranial Hemangiopericytoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Gamma-Secretase Inhibitor RO4929097|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Temozolomide|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study is Done in Patients With Plaque Psoriasis and Tests How Well They Tolerate BI 730357 and How Effective it is
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo (fasted)|DRUG: BI 25 mg (fasted)|DRUG: BI 50 mg (fasted)|DRUG: BI 100 mg (fasted)|DRUG: BI 200 mg (fasted)|DRUG: Placebo (fed)|DRUG: BI 400 mg once daily (fed)|DRUG: BI 200 mg twice daily, 400 mg total (fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis
Status: TERMINATED
Conditions: System; Sclerosis|Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Belumosudil (KD025)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Isometric Exercise on Pain Perception in Rotator Cuff Related Shoulder Pain
Status: COMPLETED
Conditions: Rotator Cuff Tendinitis
Interventions: OTHER: Supra-threshold isometric exercise|OTHER: Infra-threshold isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ahmed Valve Glaucoma Implant With Adjunctive Subconjunctival Bevacizumab in Refractory Glaucoma
Status: UNKNOWN
Conditions: Refractory Glaucoma
Interventions: DRUG: Subconjunctival Avastin|DEVICE: Ahmed Valve implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcitriol and Docetaxel in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DIETARY_SUPPLEMENT: calcitriol|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibrin for Chronic Multi-level Discogenic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain|Disc Disease|Disc Degeneration|Radiculopathy|Annular Disc Tear
Interventions: DRUG: Fibrin sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PROMETRIUM® Capsules in Induction of Secretory Conversion
Status: COMPLETED
Conditions: Secondary Amenorrhea
Interventions: DRUG: PROMETRIUM® 300 mg|DRUG: PROMETRIUM® 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mindfulness-based Stress Reduction Intervention on Psychological Distress and Hope Among Female Patients Undergoing Radiotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: BEHAVIORAL: Mindfulness-based stress reduction intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CP-690,550 + methotrexate|DRUG: Placebo + Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection
Status: UNKNOWN
Conditions: Early Gastric Cancer or Gastric Adenoma
Interventions: DRUG: intravenous dexamethasone|DRUG: intravenous normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Stem cell transplant x 1 or x 2|DRUG: lenalidomide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bone-parathyroid Crosstalk in Primary Hyperparathyroidism
Status: NOT_YET_RECRUITING
Conditions: Hyperparathyroidism, Primary|Osteoporosis|Parathyroid Neoplasms
Interventions: DIAGNOSTIC_TEST: Biomarker assays
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)
Status: RECRUITING
Conditions: Neuromyelitis Optica Spectrum Disorders
Interventions: BIOLOGICAL: divozilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study to Investigate Biomarkers of Senescence in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Arthroscopy|PROCEDURE: Arthrocentesis|DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Omega-3 Fatty Acids for Autism Treatment
Status: COMPLETED
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acids|DIETARY_SUPPLEMENT: Omega-3 Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infliximab for the Prevention of Graft-versus-Host Disease Following Allogenic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft-Versus-Host Disease
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.
Status: COMPLETED
Conditions: HIV Infections|Cytomegalovirus|CMV
Interventions: DRUG: Letermovir 240 MG Oral Tablet|DRUG: Letermovir 480 MG Oral Tablet|DRUG: Combination ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Off taRget Effects of Linagliptin monothErapy on Arterial Stiffness in Early Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Linagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients
Status: COMPLETED
Conditions: Acute on Chronic Liver Failure
Interventions: DEVICE: DIALIVE Liver Dialysis Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treatment of Perianal Fistulas by Endorectal Advancement Flap Associated With Adipose Tissue Injection
Status: RECRUITING
Conditions: Anal Fistula
Interventions: PROCEDURE: Adipose tissue injection associated with endorectal advancement flap.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fospropofol for Same-day Bidirectional Endoscopy in Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Elderly Patients
Interventions: DRUG: fospropofol sedation|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects and Safety of Infusion of Low-Doses of Methylprednisolone in Early ALI and ARDS in Children
Status: WITHDRAWN
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: DRUG: Methylprednisolone Arm|DRUG: Sterile Saline Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversibility of Methacholine Induced Bronchoconstriction
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: salbutamol aqueous solution|DRUG: salbutamol pressurized metered dose inhaler|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Diagnostic Assay for Gonorrhea and Chlamydia
Status: RECRUITING
Conditions: Urethritis|Cervicitis|Sexually Transmitted Infections
Interventions: DIAGNOSTIC_TEST: Rapid 30-minute Desktop Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Complex Intervention for Chronically Fatigued Lymphoma Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Fatigue Syndrome
Interventions: OTHER: Interdisciplinary complex intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Fish Oil-enriched Lipid Emulsion on Fatty Acid and Inflammatory Response in Infants After Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: OTHER: SMOFlipid 20%|OTHER: Lipofundin 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asian Diabetes Outcomes Prevention Trial
Status: RECRUITING
Conditions: Diabetes Mellitus|Cardiovascular Diseases
Interventions: DRUG: Renin-angiotensin-aldosterone system inhibitors|DRUG: Beta blocker|DRUG: SGLT2 Inhibitor - Sodium Glucose Cotransporter Subtype 2 Inhibitor Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BI 765128 in Patients With an Eye Condition Called Diabetic Macular Ischemia Who Have Received Laser Treatment
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: BI 765128|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab|DRUG: Ocrelizumab|DRUG: Antihistamine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: IMO-2055|DRUG: Cetuximab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Ethinyl Estradiol/Etonogestrel Vaginal Ring
Status: COMPLETED
Conditions: Healthy Women|Female|Contraception
Interventions: COMBINATION_PRODUCT: EVE119 vaginal ring|COMBINATION_PRODUCT: Nuvaring vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION