pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimodal Neuroimaging Study
Status: COMPLETED
Conditions: Dementia With Lewy Bodies|Alzheimer Disease|Self|Autobiographical Memory|Insular Cortex
Interventions: OTHER: Neuropsychological assessment and Multimodal brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Remote Ischemic Preconditioning Induces Myocardial RISK Signaling Pathway in Patients Undergoing Valvular Heart Surgery
Status: COMPLETED
Conditions: Patients With Elective Aortic Valve Replacement
Interventions: PROCEDURE: Remote ischemic preconditioning at left upper arm|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Bacillus Cereus in the Prevention of Afatinib-associated Diarrhea
Status: TERMINATED
Conditions: Diarrhea|Treatment Side Effects
Interventions: DRUG: Bacillus Cereus tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Amoxicillin|DRUG: Metronidazole|DRUG: Clarithromycin|DRUG: Pantoprazole 40mg|DRUG: according to antibiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Effect of Nab-paclitaxel Combined to Gemcitabine in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Nab-paclitaxel + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Eye and Irritation Comparison of Latanoprost With the Preservative Versus Travoprost Without Preservative
Status: COMPLETED
Conditions: Ocular Dryness|Ocular Irritation|Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travaprost without BAC (Travatan Z)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Intra- and Interpersonal Multimodal Synchronizations in a Social Interaction in Individuals With a Diagnosis of Schizophrenia.
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Social interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addressing Durable Health Disparities Through Critical Time Legal Interventions in Medically Underserved Latinx and Migrant Communities
Status: NOT_YET_RECRUITING
Conditions: Health Harming Legal Needs
Interventions: OTHER: Critical Time Medical-Legal Partnership Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Web-mediated Follow-up With the Web-application KidneyPRO Versus Standard Follow-up for Patients With Advanced Renal Cell Carcinoma Treated With Axitinib/Pembrolizumab in First Line
Status: RECRUITING
Conditions: Renal Cell Carcinoma Metastatic
Interventions: DEVICE: KidneyPRO|OTHER: standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: E-Health Support Program (PACK Health Program) in Supporting Patient Reported Symptoms in Newly Diagnosed Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma
Interventions: OTHER: Questionnaire Administration|PROCEDURE: Supportive Care|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: External Nasal Dilator and Oxygen Therapy in Respiratory Failure
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: External nasal dilator (END)|OTHER: High flow nasal cannula (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Epizon-701 (EPN-701) in Subjects With End-Stage Renal Disease (ESRD)
Status: COMPLETED
Conditions: End-Stage Renal Disease (ESRD)
Interventions: DRUG: EPN-701 (Oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
Status: RECRUITING
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Bortezomib|DRUG: Daratumumab and Hyaluronidase-fihj|DRUG: Dexamethasone|DRUG: Lenalidomide|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Participants With Advanced and/or Refractory Solid Tumors (MK-5108-001)
Status: COMPLETED
Conditions: Cancer, Neoplasms, Tumors
Interventions: DRUG: MK-5108|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and PK of PCS6422 (Eniluracil) With Capecitabine in Patients With Advanced, Refractory GI Tract Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer|Refractory Cancer|Tumor Gastric
Interventions: DRUG: PCS6422 and capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Lapatinib (GW572016) In Patients With Relapsed Adenocarcinoma Of The Esophagus
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: DRUG: Lapatinib (GW572016) oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia|Osler Weber Rendu Disease
Interventions: DRUG: Propranolol treatment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Compare Abcertin and EU-sourced Cerezyme® in Healthy Volunteers
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: DRUG: Abcertin|DRUG: EU-sourced Cerezyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Burger Allen Exercises in Knee OA With Type II Diabetes
Status: COMPLETED
Conditions: Knee Osteoarthritis|Type II Diabetes
Interventions: OTHER: thermotherapy+ TENS+ low intensity high repetition exercises and Buerger Allen|OTHER: thermotherapy+ TENS+ low intensity high repetition exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluzoparib and Apatinib Versus Fluzoparib in Relapsed Ovarian Carcinoma Maintenance Treatment
Status: NOT_YET_RECRUITING
Conditions: Relapsed Ovarian Cancer
Interventions: DRUG: Fluzoparib+Apatinib|DRUG: Fluzoparib Monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid Syndrome
Status: TERMINATED
Conditions: Malignant Carcinoid Syndrome
Interventions: DRUG: lanreotide Autogel (somatostatin analogue)|DRUG: Sandostatin long acting release (LAR) Depot (somatostatin analogue)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of Meplazumab in Treatment of Post-COVID-19
Status: COMPLETED
Conditions: Post-COVID-19
Interventions: BIOLOGICAL: Meplazumab for injection|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: lenvatinib|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frailty Assessment and Intervention in Elderly Patients With Gastric Cancer Receiving Gastrectomy and Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: BEHAVIORAL: Frailty intervention measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Controlled Study of Humira in Subjects With Chronic Plaque Psoriasis of the Hands and/or Feet
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec in Treating Patients With Non-Muscle Invasive Bladder Transitional Cell Carcinoma
Status: WITHDRAWN
Conditions: Stage 0 Bladder Urothelial Carcinoma AJCC v6 and v7|Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7|Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7|Stage I Bladder Urothelial Carcinoma AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Hyperpolarized Helium-3|DRUG: Placebo|DRUG: Aformoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain
Status: COMPLETED
Conditions: Analgesics, Opioid|Pain
Interventions: DRUG: OROS hydromorphone HCI (slow release)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain During Femoral Sheath Removal in Patients Undergoing Percutaneous Coronary Intervenion
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention|Virtual Reality|Nursing Caries|Cryotherapy|Pain Management
Interventions: OTHER: Virtual Reality Glasses|OTHER: Ice Application Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Educational Module and Decision Counseling Program in Increasing Mammography Screening Rates in Formerly Homeless Women With Serious Mental Illness
Status: COMPLETED
Conditions: Breast - Female
Interventions: OTHER: Educational Intervention|OTHER: Counseling|OTHER: Informational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum
Status: COMPLETED
Conditions: Rectum Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab|RADIATION: Radiotherapy|DRUG: Capecitabine during all Radiotherapy period|PROCEDURE: Total Mesorectal Excision (TME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Durvalumab|DRUG: Selumetinib|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ThisCART19A Bridging to alloHSCT for R/R B-ALL
Status: RECRUITING
Conditions: CAR|Refractory Acute Lymphoblastic Leukemia|Relapsed Adult ALL
Interventions: DRUG: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery
Status: TERMINATED
Conditions: Ulcerative Colitis|Familial Polyposis
Interventions: DEVICE: SprayShield Adhesion Barrier System|PROCEDURE: Good Surgical Technique Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Effectiveness of Different Interventions for Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Biofeedback|Pelvic Floor
Interventions: OTHER: Exercise|OTHER: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Complex Weight-reducing Interventions on Rhythm Control in Obese Subjects With Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Obesity
Interventions: BEHAVIORAL: Physician-lead complex program of weight-reducing interventions|PROCEDURE: Bariatric surgery - sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Colon Cancer|Rectal Cancer
Interventions: BIOLOGICAL: RNF43, TOMM34, VEGFR1 and VEGFR2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Divided Dose of TRAVATAN®
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost Ophthalmic Solution, 0.00013%|DRUG: Travoprost Ophthalmic Solution, 0.00033%|DRUG: Travoprost Ophthalmic Solution, 0.001%|DRUG: Travoprost Ophthalmic Solution, 0.00267%|DRUG: Travoprost Ophthalmic Solution, 0.004%|DRUG: Travoprost Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Flash Glucose Monitoring System in Patients With Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DEVICE: CareSens N (iSENS)|DEVICE: Freestyle Libre (Abbott)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assisted Fluid Management (AFM) System and Postoperative Outcome After High-risk Abdominal Surgery
Status: RECRUITING
Conditions: Decision Support System|Outcome
Interventions: PROCEDURE: Routine care|DEVICE: AFM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Pharmacokinetics and Safety of CKD-333 With Co-administration CKD-330 and D090 in Healthy Male Adults
Status: UNKNOWN
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: CKD-333, formula I|DRUG: CKD-333, formula II|DRUG: CKD-330, D090
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Electrical Muscle Stimulation During Stem Cell Transplantation or Intensive Chemotherapy
Status: COMPLETED
Conditions: Electric Stimulation Therapy
Interventions: DEVICE: Myopuls 2000D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of In-Stent Restenosis by Paclitaxel Coated PTCA Balloons (PACCOCATH - ISR I)
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: PTCA|COMBINATION_PRODUCT: paclitaxel coated balloon catheter (device with drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and Outcome of Adult Acute Lymphoblastic Leukemia (ALL) Patients and Related Diseases Associated With a Prospective Collection of Biomaterial
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Leukemia|Non-Hodgkin's Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Decompressive Craniectomy for Severe Traumatic Brain Injury in Children With Refractory Intracranial Hypertension
Status: WITHDRAWN
Conditions: Hypertension Intracranial
Interventions: PROCEDURE: decompressive craniectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GSK2110183 in Subjects With Proteasome Inhibitor Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: Part 1; Cohort 1|DRUG: Part 1; Cohort 2|DRUG: Part 2; Stage 1|DRUG: Part 2, Stage 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: xSPECT-based Myocardial Perfusion Scintigraphy: Consistency of Functional Values and Feasibility of Myocardial Uptake Quantitation in Patients With Suspected Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: 99mTc-sestamibi myocardial perfusion SPECT|DIAGNOSTIC_TEST: 82Rb-Chloride myocardial perfusion PET with CCTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Accelerated Short Course Radiation Therapy With Photons and Capecitabine for Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: RADIATION: Neoadjuvant Short-Course Photon Radiation|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Osimertinib + Chemotherapy for EGFR-mutant Stage III NSCLC
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy on Osteoblast-Like Cells In- Vitro Study
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DEVICE: Extracorporeal shockwave device|DEVICE: No ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Performance of an Injective Treatment for the Skin Roughness and Laxity of Inner Arm and Abdomen
Status: COMPLETED
Conditions: Skin Flaccidity and Roughness of the Abdomen and Inner Arms
Interventions: DEVICE: Profhilo®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caudal vs Local Anesthesia in Hypospadias
Status: RECRUITING
Conditions: Hypospadias
Interventions: DRUG: Caudal Block Anesthesia|DRUG: Dorsal Penile Block Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Financial Navigation Program to Improve Understanding and Management of Financial Aspects of Cancer Care for Patients and Their Spouses
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|BEHAVIORAL: Patient Navigation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-response Effect of the Thickener Tsururinko Quickly
Status: UNKNOWN
Conditions: Dysphagia|Dysphagia, Oral Phase|Dysphagia, Oropharyngeal|Dysphagia, Esophageal|Swallowing Disorder
Interventions: OTHER: Xanthan-gum based thickener
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research of Revascularization in Immature Teeth With Periapical Periodontitis
Status: UNKNOWN
Conditions: Periapical Periodontitis
Interventions: PROCEDURE: revascularization|PROCEDURE: apexification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Re-irradiation For Locoregionally Recurrent Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Loco-regionally Recurrent NSCLC After Thoracic Radiotherapy
Interventions: RADIATION: thoracic irradiation|DRUG: Concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Herbal Galactagogue Silitidil After Preterm Birth
Status: COMPLETED
Conditions: Breast Milk Production|Human Milk Feeding|Hypogalactia|Preterm Infant Nutrition
Interventions: DIETARY_SUPPLEMENT: Silitidil for 21 days|DIETARY_SUPPLEMENT: Placebo for 21 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Procenta® Conformable Barrier for Non-Healing Foot & Ankle Ulcers in Patients With Diabetes Mellitus Types I and II
Status: UNKNOWN
Conditions: Foot Ulcer, Diabetic
Interventions: BIOLOGICAL: Procenta conformable barrier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CARFILZOMIB, CYCLOPHOSPHAMIDE, DEXAMETHASONE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heat Therapy and Muscle Function Study
Status: RECRUITING
Conditions: Exercise Intolerance|Aging|Heat Therapy|High Intensity Interval Training
Interventions: OTHER: High Intensity Interval Training of the Knee Extensors|OTHER: Muscle Heat Therapy|OTHER: Muscle Disuse|OTHER: Sham Heat Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota and Metabonomics
Status: RECRUITING
Conditions: Stomach Neoplasms|Gut Microbiota|Metabolomics
Interventions: PROCEDURE: Healthy control specimen collection|PROCEDURE: Non-Borrmann IV patient specimen collection|PROCEDURE: Borrmann IV patient specimen collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: rosiglitazone|DRUG: metformin or sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ganoderma on Patients With Head-and-neck Cancer
Status: UNKNOWN
Conditions: Head-and-neck Cancer
Interventions: OTHER: Control group|DIETARY_SUPPLEMENT: Ganoderma Spores Powder Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Early Counseling and Support for Alzheimer's Disease Caregivers
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: BEHAVIORAL: Psychosocial Intervention|BEHAVIORAL: Educational Intervention on AD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMA of Substance Use in Homeless Youth
Status: COMPLETED
Conditions: Substance Use
Interventions: BEHAVIORAL: Ecological Momentary Assessment (EMA; Metricwire) Prompts 3x/day|BEHAVIORAL: Ecological Momentary Assessment (EMA; Metricwire) Prompts 6x/day|BEHAVIORAL: Incentive Structure - fixed|BEHAVIORAL: Incentive Structure - prize based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Botox-A Injection to Improve Bladder Function in Early Spinal Cord Injury (#H-20344)
Status: TERMINATED
Conditions: Neurogenic Bladder Dysfunction Nos|Spinal Cord Injury
Interventions: DRUG: BOTOX-A|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia
Status: COMPLETED
Conditions: Auditory Verbal Hallucinations|Schizophrenia
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: Fosmanogepix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Research Study Looking at Long-term Blood Sugar Control in People With Type 2 Diabetes Being Treated With Xultophy® in a Real-world Setting in Italy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec and liraglutide (IDegLira)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin & Inflammation in Pre-diabetic Children
Status: COMPLETED
Conditions: Glucose Intolerance|Inflammation|Diabetes
Interventions: DRUG: Metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Audio Recorded Guided Imagery vs Deep Breathing Exercises on Functional Gastrointestinal Pain Disorders
Status: COMPLETED
Conditions: Abdominal Pain|Functional Gastrointestinal Disorders
Interventions: DEVICE: Apple iPod Shuffle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: X-ray-free Protocol for Pectus Deformities Based on Magnetic Resonance 1 Imaging and a Low-cost Portable Three-dimensional Scanning Device
Status: COMPLETED
Conditions: Pectus Deformity
Interventions: DEVICE: chest CT|DEVICE: Magnetic Resonance Imaging and a low-cost portable three-dimensional scanning device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RESECTED LYMPH NODES AND SURVIVAL OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA: AN OBSERVATIONAL STUDY
Status: RECRUITING
Conditions: the Records of Esophageal Cancer
Interventions: DIAGNOSTIC_TEST: Since the data were collected retrospectively, there were no interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin in Obese Patients in Laparoscopic Cholecystectomy
Status: NOT_YET_RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Melatonin|DIETARY_SUPPLEMENT: Vitamin Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korean Patients
Status: COMPLETED
Conditions: Urinary Incontinence|Overactive Bladder
Interventions: BIOLOGICAL: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diet and Exercise Interventions on Cardiometabolic Risk Markers, Executive Function, and Intestinal Flora
Status: UNKNOWN
Conditions: Cardiometabolic Risk|Executive Function|Intestinal Microbiome
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 4 Study to Evaluate Pharmacokinetics and Safety of Darunavir Along With Ritonavir in Healthy Male Japanese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Taliderm® and Vacuum-assisted Closure (VAC) for Treatment of Pressure Ulcers
Status: TERMINATED
Conditions: Wounds|Pressure Ulcer
Interventions: OTHER: wound dressing with VAC and sNAG without antiaggregation|PROCEDURE: wound dressing with VAC|DRUG: wound dressing with VAC and sNAG under Antiaggregation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Sexual Desire and Metabolic Syndrome
Status: COMPLETED
Conditions: Menopause|Metabolic Syndrome|Hypoactive Sexual Desire Disorder|Obesity|Sexual Dysfunction
Interventions: DIAGNOSTIC_TEST: Female sexual function index questionnaire|DIAGNOSTIC_TEST: Evaluation of presence of metabolic syndrome|DIAGNOSTIC_TEST: Evaluation of the body mass index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Outcomes of Two Approaches in Microsurgical Varicocelectomy in Chinese Infertile Males: A Prospective Randomized, Controlled Trial
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: microsurgical varicocelectomy in inguinal approach|PROCEDURE: microsurgical varicocelectomy in subinguinal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Gabapentin|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Status: UNKNOWN
Conditions: Dental Pulp Necroses
Interventions: OTHER: no intervention|BIOLOGICAL: Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: PEGPH20|DRUG: Cetuximab|DEVICE: DW & DCE-MRI|OTHER: blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Treatment for OSA in Children
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Dexamethasone|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: rifabutin in combination with efavirenz|DRUG: rifabutin in combination with nevirapine|DRUG: rifabutin in combination with lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1291583 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1291583|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmation of Tube Placement in Newborns
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome|Apnea of Newborn
Interventions: PROCEDURE: Nostril-Tragus-Length|PROCEDURE: Vocal cord marking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of Cediranib and Olaparib Maintenance in Advanced Recurrent Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: Cediranib, Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Narrow-Band UVB Radiations
Status: COMPLETED
Conditions: Psoriasis Vulgaris|UVB Phototherapy Burn
Interventions: DIAGNOSTIC_TEST: Serum Interleukin 17 levels|RADIATION: NB-UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Etoricoxib vs. Diclofenac in OA (0663-805)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib / Duration of Treatment: 6 Weeks|DRUG: Comparator: diclofenac sodium / Duration of Treatment: 6 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Counseling Intervention Trial to Reduce Alcohol-related Sexual Risk Behavior Among HIV-negative Men in Namibia
Status: COMPLETED
Conditions: Alcohol Consumption|Alcohol Abuse|HIV|Sexual Behavior
Interventions: BEHAVIORAL: Alcohol-HIV Risk Reduction Counseling|BEHAVIORAL: Placebo Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Long-Term Antibiotic Treatment in Reactive Arthritis
Status: COMPLETED
Conditions: Reactive Arthritis
Interventions: DRUG: ofloxacin and roxithromycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2484595 on the Electrical Activity of the Heart
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2484595|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Regimens for Patients With Resectable Liver Metastases (PANTER Study)
Status: TERMINATED
Conditions: Liver Metastasis
Interventions: PROCEDURE: adjuvant surgery + FOLFOX + cetuximab|PROCEDURE: perioperative/Folfox + cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Protein Timing and Resistance Exercise on Fat Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Micellar Casein Protein|OTHER: Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Evaluating Carbon Ion Radiotherapy With Concurrent Chemotherapy for Locally Recurrent Nasopharyngeal Carcinoma
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Carbon ion radiotherapy (CIRT)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Levetiracetam (Keppra) on Alcohol Consumption
Status: COMPLETED
Conditions: Alcohol Abuse|Drug Abuse
Interventions: DRUG: Levetiracetam (Keppra)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy
Status: UNKNOWN
Conditions: HNSCC|Head and Neck Neoplasms
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Contribution of Nasal High Flow in Pneumology Assessed in Acid-Free Hypercapnic Acute Respiratory Failure
Status: RECRUITING
Conditions: Respiratory Insufficiency
Interventions: DEVICE: AIRVO3 TM|OTHER: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Dosing of Nicotine Replacement (NRT to Effect)
Status: COMPLETED
Conditions: Tobacco Use Disorder|Nicotine Dependence
Interventions: DRUG: Nicotine Patch|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lessening Organ Dysfunction With VITamin C in Septic ARDS
Status: RECRUITING
Conditions: Septic|Acute Respiratory Distress Syndrome
Interventions: DRUG: Administration of vitamin C|DRUG: Administration of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
Status: RECRUITING
Conditions: Pelvic Organ Prolapse|Perioperative/Postoperative Complications
Interventions: DRUG: Gabapentin|DRUG: Gabapentin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zingiber and Acmella Against Knee Osteoarthritis
Status: COMPLETED
Conditions: Pain|Osteo Arthritis Knee
Interventions: DIETARY_SUPPLEMENT: Zingiber officinale and Acmella oleracea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Heart Disease|Tetrology of Fallot|RVOT Anomaly|Pulmonary Regurgitation
Interventions: DEVICE: Harmony TPV System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Electrodry Needlig and Dry Needling in Mechanical Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Quadratus Lumborum Syndrome
Interventions: OTHER: Electro Dry Needlig|OTHER: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Harmonic Endoscopic Ultrasound (CH-EUS), Elastography, and Fractal Analysis in Predicting Pancreatic Cancer Aggressiveness and Response to Therapy.
Status: RECRUITING
Conditions: Pancreatic Mass
Interventions: PROCEDURE: Contrast enhanced harmonic Endoscopic Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adaptive Immune Responses and Repertoire in Influenza Vaccination and Infection (SLVP031)
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone®|BIOLOGICAL: FluMist®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Efficacy and Safety of LX201 for Prevention of Corneal Allograft Rejection Episodes and Graft Failure in Subjects at Increased Immunological Risk
Status: TERMINATED
Conditions: Corneal Diseases|Cornea Transplant
Interventions: DRUG: LX201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA®
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: OTHER: Spinraza intrathecal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficiency of Vaccination With Lysate-loaded Dendritic Cells in Patients With Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Autologous, tumor lysate-loaded, mature dendritic cells (DC)|DRUG: standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Anthocyans on Cardiovascular and Sympathetic Function
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Anthocyans|OTHER: placebo|DIETARY_SUPPLEMENT: Anthocyans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Progesterone Therapy on Traumatic Subarachinoid Haemorrhage on Clinical Outcome and Resistive Vasculer Indices of Middle Cerebral Artery Transcranial Doppler
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia
Status: TERMINATED
Conditions: Relapsed or Refractory Acute Lymphoblastic Leukemia|Relapsed or Refractory Lymphoblastic Lymphoma|Mixed Phenotype Acute Leukemia
Interventions: DRUG: MLN9708|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Active Swallowing Rehabilitation on Quality of Life of Patients Treated by Radiotherapy for Head and Neck Cancer
Status: TERMINATED
Conditions: Cancer of Head and Neck
Interventions: OTHER: Swallowing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Proteome-based Immunotherapy of Lung Cancer Brain Metastases
Status: UNKNOWN
Conditions: Neoplasm Metastasis
Interventions: BIOLOGICAL: Dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes|BIOLOGICAL: Dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Safety and Efficacy Evaluation on Subjects Who Completed PNEUMOSTEM® Phase-II Clinical Trial
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: Pneumostem®|BIOLOGICAL: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Excess Risk in Aortic Stenosis
Status: RECRUITING
Conditions: Aortic Stenosis|Non-Sustained VT|Heart Failure
Interventions: DIAGNOSTIC_TEST: Cardiac MRI scan|DIAGNOSTIC_TEST: Serum biomarkers (High sensitivity troponin, NT-proBNP|PROCEDURE: Implantable Loop Recorder|DIAGNOSTIC_TEST: 6 minute walk test|DIAGNOSTIC_TEST: Echocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p