pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Course of Interstitial Lung Diseases: European IPF Registry and Biobank
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis|Idiopathic Interstitial Pneumonia|Interstitial Lung Diseases|Diffuse Parenchymal Lung Diseases
Interventions: OTHER: patient registry (observation and biomaterial sampling)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2
Status: NOT_YET_RECRUITING
Conditions: Obesity|Chronic Kidney Disease
Interventions: DRUG: Semaglutide|BEHAVIORAL: Virtual Weight Management Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Menstrual Health Education for Visually Impaired Adolescent
Status: NOT_YET_RECRUITING
Conditions: Visual Impairment|Menstrual Problem
Interventions: DEVICE: web based education|BEHAVIORAL: Face to face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Speech Locator In-car Performance Evaluation
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Investigational adaptive directional microphone strategy|DEVICE: Comparator omnidirectional microphone strategy|DEVICE: Comparator fixed directional microphone strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Specific Pelvic Stabilization Exercise in Postpartum Pregnancy-related Pelvic Girdle Pain Women
Status: WITHDRAWN
Conditions: Pelvic Girdle Pain
Interventions: OTHER: pelvic floor muscle training|OTHER: pelvic floor muscle combined global muscle exercise training|OTHER: education of pelvic girdle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Combination With Fludarabine and Cyclophosphamide in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic, Chronic Lymphocytic Leukemia, Cancer
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CD19-targeting, 3rd Generation CAR T Cells for Refractory B Cells Malignancy
Status: COMPLETED
Conditions: B-cell Leukemia|B-Cell Lymphoma
Interventions: BIOLOGICAL: CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of the Safety and Immunogenicity of BSAM-2/Alhydrogel +CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria in Adults in the US and Mali
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: BSAM2/Alhydrogel + CPG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors and Carcinomas
Status: RECRUITING
Conditions: Neuroendocrine Carcinomas|Neuroendocrine Tumors|Carcinoma, Neuroendocrine|Carcinoma, Adrenocortical|Carcinoma, Adrenal Cortical
Interventions: DRUG: ADCT-701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise, Dietary Counseling and Cognitive Behavioral Training as a Combined Intervention to Reduce Weight and Increase Workability in Health Care Workers
Status: COMPLETED
Conditions: Overweight|Physical Capacity|Musculoskeletal Diseases|Work Ability|Sick-leave
Interventions: BEHAVIORAL: Intervention-group|BEHAVIORAL: Control-group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prurigo Nodularis
Interventions: DRUG: Nemolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compressive Elastic Dressing Versus TR Band
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Angina, Unstable|Angina, Stable|Acute Coronary Syndrome|STEMI|NSTEMI|Ischemic Heart Disease|Atherosclerotic Cardiovascular Disease|Chest Pain|Non ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Compressive Elastic dressing for hemostasis in cardiac procedure using radial approach|PROCEDURE: Wristband TR band for hemostasis in cardiac procedure using radial approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing Negative Pressure Dressings to Conventional Dressings
Status: WITHDRAWN
Conditions: Venous Leg Ulcer
Interventions: DEVICE: PICO Negative Pressure Wound Therapy|PROCEDURE: Compression Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: CLONIDINE|DRUG: CAPTOPRIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Relapsed or Refractory Acute Myeloid Leukemia (AML)|Acute Myeloid Leukemia (AML), Secondary to Myeloproliferative Neoplasms (MPN)
Interventions: DRUG: KRT-232|DRUG: Cytarabine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3841136 in Japanese Participants With Obesity or Overweight
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: LY3841136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis
Status: UNKNOWN
Conditions: IgA Vasculitis
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease
Status: UNKNOWN
Conditions: Peripheral Vascular Disease
Interventions: DRUG: Liprostin [liposomal Prostaglandin E1]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real Time Continuous Glucose Monitoring System in T2DM With Pregnacy
Status: RECRUITING
Conditions: Type2diabetes|Pregnancy Related|Continuous Glucose Monitoring|Time in Range|Pregnancy Outcome
Interventions: DEVICE: Real-time Continuous Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Satisfaction With Actonel in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Risedronate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: DRUG: dexmedetomidine|PROCEDURE: Vital signs|PROCEDURE: blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SD-OCT Multimodal Analysis in GLaucoma
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Eye Diseases
Interventions: DEVICE: SD-OCT Spectralis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial
Status: RECRUITING
Conditions: Ischemia Reperfusion Injury|Myocardial Injury|Acute Kidney Injury
Interventions: DRUG: Niacinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PSA-Based Vaccine and Radiotherapy to Treat Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Neoplasm
Interventions: DRUG: rV-PSA|DRUG: rF-PSA|DRUG: rV-B7.1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Single Oral Dose Escalation Study of DNDI-0690 in Healthy Subjects
Status: COMPLETED
Conditions: Visceral Leishmaniasis|Cutaneous Leishmaniases
Interventions: DRUG: DNDI-0690|DRUG: Placebo of DNDI-0690
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Preliminary Efficacy Study of CDZ173 in Patients With Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: CDZ173|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multislice Spiral Computed Tomography and Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathies
Interventions: PROCEDURE: Multislice spiral computed tomography coronary angiography|PROCEDURE: conventional coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Teduglutide|OTHER: Standard Medical Therapy|DEVICE: Syringe|DEVICE: Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Status: COMPLETED
Conditions: Social Anxiety Disorder|Social Anxiety|Social Anxiety Disorder of Childhood
Interventions: OTHER: animal-assisted intervention|OTHER: active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR]
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Survival of Patients With Colorectal Cancer 5 Years After Surgery - Follow-up of the RCT DIQOL
Status: COMPLETED
Conditions: Quality of Life|Colorectal Cancer|Colorectal Neoplasms|Survivorship
Interventions: BEHAVIORAL: Quality of life diagnosis and therapy during the completed RCT DIQOL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fed Conditions
Status: COMPLETED
Conditions: Herpes Zoster|Shingles|Genital Herpes
Interventions: DRUG: Valacyclovir Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation
Status: RECRUITING
Conditions: COPD|COPD Exacerbation Acute
Interventions: DEVICE: Telemonitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers
Status: RECRUITING
Conditions: DIPG|Brain Tumor, Pediatric, Recurrent|Brain Tumor, DIPG|Radiation Toxicity|Radiation Exposure|Brain Tumor, Pediatric
Interventions: OTHER: This study does not include an intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fecal Microbial Transplantation and Fiber Supplementation in Participants With Obesity and Metabolic Syndrome.
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: BIOLOGICAL: FMT|BIOLOGICAL: Placebo FMT|DIETARY_SUPPLEMENT: Prebiotic Fiber|DIETARY_SUPPLEMENT: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AML Therapy With Irradiated Allogeneic Cells
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: fludarabine phosphate|DRUG: cytarabine|BIOLOGICAL: donor lymphocytes|OTHER: laboratory biomarker analysis|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposome-encapsulated Irinotecan Hydrochloride PEP02 or Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil as Second-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI 1-Bevacizumab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: liposome-encapsulated irinotecan hydrochloride PEP02|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: phenylephrine|DRUG: pseudoephedrine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With Cemiplimab or REGN5678 for Adult Participants With Advanced Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: REGN4336|DRUG: Cemiplimab|DRUG: REGN5678|DRUG: Sarilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dairy Products on Postprandial Inflammation
Status: COMPLETED
Conditions: Inflammation|Obesity|Nutritional Intervention
Interventions: OTHER: consumption of test meal based on dairy products|OTHER: consumption of high fat test meal without dairy products|OTHER: consumption of high fat test meal with dairy products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Bystander Intervention Program in Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Bystander Effect|Dating Violence|Nursing Students|Intimate Partner Violence
Interventions: OTHER: Bystander Intervention Program for Dating Violence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Deep Brain Stimulation of Nucleus Accumbens for Opioid Relapse Prevention
Status: UNKNOWN
Conditions: Addiction
Interventions: DEVICE: Suzhou Sceneray® DBS System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.
Status: NOT_YET_RECRUITING
Conditions: Primary Open Angle Glaucoma|Glaucoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: [18F]FLT PET/CT in Rb+ Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasm|Metastatic Breast Cancer|Rb+ Breast Cancer
Interventions: DRUG: [18F]FLT|DEVICE: PET/CT|DRUG: ribociclib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Ascending Dose (SAD)/Multiple Ascending Dose(MAD) Safety/Pharmacokinetic (PK) Study of KM-023
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: KM-023|DRUG: Placebo for KM-023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Four-Arm Study Comparing the Analgesic Efficacy and Safety of Tramadol Once a Day 100, 200 and 300 mg Versus Placebo for the Treatment of Pain Due to Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Pain|Osteoarthritis, Knee
Interventions: DRUG: Tramadol Once A Day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fat Grafting in Reducing Recurrence in Patients With Healed Venous Ulcers A Prospective Randomised Clinical Pilot Study
Status: UNKNOWN
Conditions: Varicose Ulcer
Interventions: PROCEDURE: Fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant COVID-19 Vaccine (CHO Cell, NVSI-06-09) Phase III Clinical Trial
Status: RECRUITING
Conditions: COVID-19|Coronavirus Infections
Interventions: BIOLOGICAL: LIBP-Rec-Vaccine|BIOLOGICAL: BIBP-Rec-Vaccine|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EON: A Single-arm Phase II Study of Etigilimab (OMP-313M32) in Combination With Checkpoint Inhibition (Nivolumab) in Patients With Platinum-resistant, Recurrent Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Nivolumab|DRUG: Etigilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Adult Hepatocellular Carcinoma|Child-Pugh Class A|Stage III Hepatocellular Carcinoma|Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IV Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation Into the Safety and Scar-improvement Efficacy of Intradermal Juvidex Dosed Once or Three Times
Status: COMPLETED
Conditions: Cicatrix|Wound-healing
Interventions: DRUG: Juvidex|DRUG: Juvidex|DRUG: Juvidex|DRUG: Juvidex|DRUG: Juvidex|DRUG: Juvidex|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Status: RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: GLSI-100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Assisted Versus Open Resection for Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: PROCEDURE: Laparoscopic assisted resection of colorectal carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ulocuplumab And Ibrutinib in Symptomatic Patients With Mutated CXCR4 Waldenstrom's Macroglobulinemia
Status: TERMINATED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Ulocuplumab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and Adrenomyeloneuropathy
Status: COMPLETED
Conditions: Hereditary Spastic Paraplegia|Adrenomyeloneuropathy
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Whole Body Distribution and Radiation Dosimetry of the Positron Emission Tomography Ligand Fluoride-18 (18F)-JNJ-64326067 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 18F-JNJ-64326067
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adolescents and Young Adults (AYAs) With Advanced Cancer
Status: RECRUITING
Conditions: Adolescent and Young Adult Cancer Patient
Interventions: BEHAVIORAL: Symptom Management for Improved Physical and Emotional Wellbeing (SMILE)|BEHAVIORAL: Education Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-based Training on Cognitive Dysphagia in Stroke Survivors
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: routine rehabilitation treatment|BEHAVIORAL: Computer-assisted Cognitive Function Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers
Status: RECRUITING
Conditions: Keratitis|Corneal Ulcer
Interventions: COMBINATION_PRODUCT: PXL Platinum 330 system + Riboflavin 0.25% TE Solution|OTHER: Sham CXL + Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Robot Gait Training With Brain Stimulation on Gait Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Robot gait training|DEVICE: Brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematologic Cancer or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Non-responders Who Previously Participated in Eltrombopag Studies TPL 103922 or TPL 108390
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Eltrombopag|DRUG: Antiviral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENHANCED Device Programming to Reduce Therapies and Improve Quality of Life in Implantable Cardioverter Defibrillator (ICD) Patients
Status: UNKNOWN
Conditions: Cardiac Arrhythmias
Interventions: DEVICE: Enhanced ICD programming
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-DOTATATE PET/CT in Oncogenic Osteomalacia
Status: UNKNOWN
Conditions: Oncogenic Osteomalacia|Mesenchymal Tumor
Interventions: DRUG: 68Ga-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumours|Squamous Cell Carcinoma of Head and Neck|Carcinoma, Non-Small-Cell Lung|Colorectal Neoplasms|Triple Negative Breast Neoplasms|Carcinoma, Renal Cell (Clear Cell Only)|Esophageal Neoplasms|Stomach Neoplasms (Excluding Gastrointestinal Stromal Tumors)|Uterine Cervical Neoplasms|Ovarian Neoplasms|Pancreatic Neoplasms
Interventions: DRUG: UCB4594
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guiding Sufentanil Administration With Skin Conductance in Mechanically Ventilated Intensive Care Patients
Status: UNKNOWN
Conditions: Nociceptive Pain
Interventions: PROCEDURE: Skin conductance guided antinociception|PROCEDURE: Standard care antinociception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Treatment to Reduce Burning Pain in Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: PROCEDURE: Lyndhurst Central Neuropathic Pain Acupuncture Protocol (LCCNPAP)|PROCEDURE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Erlotinib for Operable Stage II or IIIA NSCLC With EGFR Mutations
Status: UNKNOWN
Conditions: NSCLC Stage II|NSCLC, Stage IIIA
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Shinabro in Hand Osteoarthritis
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: DRUG: Shinbaro|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immune Response After Periodontal Treatment
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DEVICE: Hand Instrumentation Treatment|DEVICE: Ultrasonic Instrumentation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray
Status: COMPLETED
Conditions: Sore Throat|Cough|Hoarseness|Hemodynamic Instability
Interventions: DEVICE: MADgic Atomizer|DEVICE: Lignocaine pump spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: pyrotinib maleate|DRUG: Loperamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Ischemic Post-conditioning
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction|Ventricular Remodeling|Ventricular Dysfunction|Ischemic Reperfusion Injury
Interventions: PROCEDURE: Primary per-cutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Two Dose Regimens of Becocalcidiol in the Treatment of Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Vehicle (Placebo) applied BID|DRUG: QRX-101 75 mcg/g ointment applied QD|DRUG: QRX-101 75 mcg/g ointment applied BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Lu AA21004 in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan-Eluting Bead (DEBIRI) for Patients With Liver Metastases From Colorectal Cancer
Status: UNKNOWN
Conditions: Colon Cancer Liver Metastasis
Interventions: PROCEDURE: TACE|DRUG: Irinotecan|DEVICE: eluting-bead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Remote Exercise Training for Hispanics/Latinos With MS
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Exercise Training Program|BEHAVIORAL: Flexibility Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity, Safety and Immunogenicity Study of a Allantoic Split Inactivated Seasonal Influenza Vaccine
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: influenza vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Clinical Nutrition to Treat Lung Neoplasms And Breast Carcinoma
Status: COMPLETED
Conditions: Lung Neoplasms|Breast Neoplasms
Interventions: DRUG: GLSE compound|DRUG: Maitake mushroom extract compound|DRUG: Ginseng compound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I, Open-label Study of Absorption, Metabolism, and Excretion of Defactinib (VS-6063) in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function
Status: COMPLETED
Conditions: Cerebral Arterial Aneurysm
Interventions: DRUG: propofol postconditioning|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Status: UNKNOWN
Conditions: Refractive Errors
Interventions: DEVICE: HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analysis of Volatile Organic Compounds in Patients With Type 1 Diabetes in Induced Hypoglycaemia With a Breath Analyser
Status: COMPLETED
Conditions: Diabetes Mellitus|Metabolic Disease|Glucose Metabolism Disorders|Endocrine System Diseases
Interventions: DEVICE: Device: Sokru device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Self-myofascial Release on Hamstring Flexibility in Patients With Non Specific Low Back Pain
Status: COMPLETED
Conditions: Nonspecific Low Back Pain
Interventions: OTHER: Self myofascial release+ Conventional PT|OTHER: Conventional PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Nonspecific Immunostimulation on Changes in the Concentration of iNKT Cells
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Grass Pollen
Interventions: DRUG: Ismigen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Three Capsaicin Dermal Liquid Formulations on Epidermal Nerve Fiber Immunostaining and Sensory Function
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Capsaicin Dermal Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Sunitinib|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aged Garlic Extract Supplementation on Immune System
Status: COMPLETED
Conditions: Improvement in Immune Cell Function in Healthy Humans
Interventions: DIETARY_SUPPLEMENT: Aged garlic extract|DIETARY_SUPPLEMENT: AGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hepatocellular Carcinoma Surveillance in Cirrhotics
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Opt-out|BEHAVIORAL: Opt-out + Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Reduction of Bacteriuria in Subjects Practicing Intermittent Catheterization
Status: COMPLETED
Conditions: Bacteriuria
Interventions: DEVICE: Silver-nitrate coated catheter ("Catheter A")|DEVICE: Degradable silver particle-coated catheter ("Catheter B")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Yellow-Tinted Intraocular Lens on Standard Automated Perimetry (SAP) and Short-wavelength Automated Perimetry (SWAP) in Patients With and Without Glaucoma
Status: COMPLETED
Conditions: Cataract|Glaucoma
Interventions: PROCEDURE: Phacoemulsification with yellow-tinted intraocular lens|PROCEDURE: Phacoemulsification with yellow-tinted intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Partial Capsule Decortication on Device-related Infection in Patients Receiving Cardiac Implantable Electronic Device Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Pacemaker Complication|Infections
Interventions: PROCEDURE: Partial capsule decortication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ensartinib, Carboplatin, Pemetrexed and Bevacizumab for the Treatment of Stage IIIC or IV or Recurrent ALK-Positive Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Ensartinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Study of SOL for Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: SOL(The combination therapy of S-1, Leucovorin, and Oxaliplatin)|DRUG: mFOLFOX6(The combination therapy of 5-FU, l-LV and Oxaliplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults in Brazil With Chronic Hepatitis C Virus (HCV) Genotype 1 - 6 Infection
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: Glecaprevir/Pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)
Status: RECRUITING
Conditions: Cannabis Use|Alcohol Use, Unspecified
Interventions: OTHER: Alcohol|OTHER: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy
Status: COMPLETED
Conditions: Cardiac Disease|Surgery|Analgesia|Acute Pain|Postoperative Pain
Interventions: PROCEDURE: PARASTERNAL BLOCK|PROCEDURE: LOCAL INFILTRATION OF DRAINAGE EXIT SITES|PROCEDURE: RECTUS SHEATH BLOCK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pain Relief in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: bupivacaine|DRUG: morphine|DRUG: fentanyl|DRUG: Ketamine:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Advanced Epithelial Ovarian Carcinomas
Status: UNKNOWN
Conditions: Stage III Ovarian Carcinoma|Stage IV Ovarian Carcinoma|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: AVOVA-1|BIOLOGICAL: MC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
Status: COMPLETED
Conditions: Influenza|Respiratory Viral Infection
Interventions: DRUG: XC221|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Maxillary Labial Frenectomy: Diode Lasers Versus Surgical Scalpel
Status: RECRUITING
Conditions: High Frenum Attachment
Interventions: PROCEDURE: Control group (conventional scalpel surgery)|PROCEDURE: Diode laser group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation
Status: COMPLETED
Conditions: Metastatic Soft Tissue Sarcoma
Interventions: DRUG: MORAb-004|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EPI-MINN: Targeting Cognition and Motivation - National
Status: RECRUITING
Conditions: Psychosis|Psychosis Nos/Other|Schizophrenia|Schizo Affective Disorder|Schizoaffective Disorder|Prodromal Schizophrenia|Schizophrenia Spectrum and Other Psychotic Disorders|Schizophreniform Disorders|Major Depression With Psychotic Features|Unspecified Psychosis|Bipolar Disorder
Interventions: DEVICE: Cognitive and Social Cognitive Training|BEHAVIORAL: Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App|OTHER: Early Psychosis Coordinated Specialty Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unipedicular vs. Bipedicular Kyphoplasty for the Treatment of Osteoporotic Vertebral Fractures
Status: COMPLETED
Conditions: Vertebral Compression Fracture
Interventions: DEVICE: Kyphon® Balloon Kyphoplasty (Kyphon Inc; Sunnydale, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PORtopulmonary Hypertension Treatment wIth maCitentan - a randOmized Clinical Trial
Status: COMPLETED
Conditions: Portopulmonary Hypertension
Interventions: DRUG: Macitentan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Sensitizing Potential of PEP005 Topical Gel in Healthy Volunteers Using a Repeat Insult Patch Test Design
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PEP005 Topical Gel (0.01% concentration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Isokinetic Strengthening Training
Status: RECRUITING
Conditions: Resistance Training|Stroke|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: DEVICE: Isokinetic strengthening exercise|DEVICE: Isotonic strengthening exercise|BEHAVIORAL: isometric strengthening exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.
Status: NOT_YET_RECRUITING
Conditions: Migraine Disorders|Pain|Autoimmune Diseases|Multiple Sclerosis|Endometriosis|Rheumatoid Arthritis|Crohn Disease|Lupus Erythematosus
Interventions: BIOLOGICAL: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness Based Cognitive Therapy (MBCT) for Primary Care Patients
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: Mindfulness based cognitive therapy (MBCT)|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Pulmonary Rehabilitation on Clinical Outcomes in Children With Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma in Children|Physical Inactivity
Interventions: OTHER: Asthma Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen Citrate|DRUG: Letrozole|DRUG: Exemestane|DIAGNOSTIC_TEST: Blueprint|DIAGNOSTIC_TEST: Mammaprint
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anecortave Acetate Risk-Reduction Trial (AART)
Status: TERMINATED
Conditions: AMD
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 30 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/ML|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet
Status: COMPLETED
Conditions: High Risk Coronary Artery Disease
Interventions: DRUG: AZD5718 IR tablet|DRUG: AZD5718 oral suspension|DRUG: Rosuvastatin tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Female Stress Urinary Incontinence: Study Comparing Two Suburethral Slings, Retropubic Approach (TVT) and Trans-Obturator (TVT-O) Approach
Status: UNKNOWN
Conditions: Urinary Incontinence, Stress
Interventions: DEVICE: surgical placement of a suburethral sling tvt or tvt-o
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT