pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
Status: COMPLETED
Conditions: Hypertension in Pregnancy
Interventions: DRUG: Amlodipine|DRUG: NIFEdipine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients
Status: COMPLETED
Conditions: Renal Transplant Rejection
Interventions: DRUG: Sirolimus|OTHER: Demographic Data, Medical History, and Donor Data|PROCEDURE: Blood Draws for Control Group|PROCEDURE: Blood Draws for Experimental Group|PROCEDURE: Donor Blood Draws|OTHER: Donor Information|PROCEDURE: Kidney Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Eflornithine To Prevent Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: DRUG: Eflornithine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Changing Agendas on Sleep, Treatment and Learning in Epilepsy
Status: TERMINATED
Conditions: Rolandic Epilepsy
Interventions: DRUG: Carbamazepine|DRUG: Levetiracetam|BEHAVIORAL: Parent based sleep (PBS) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Structured Communication in the OR on Surgical Site Infections: Prospective Observational Clinical Trial
Status: COMPLETED
Conditions: Incidence of Surgical Site Infection|Short Intraoperative Briefings|Mortality|Shared Mental Model
Interventions: PROCEDURE: StOP? - Control group|PROCEDURE: StOP? - Intervention group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fludarabine, Cyclophosphamide, and Alemtuzumab in Treating Patients With Recurrent or Metastatic Renal Cell Carcinoma (Kidney Cancer) Undergoing Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: graft-versus-tumor induction therapy|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Secukinumab Efficacy and Safety Study in Patients With Rheumatoid Arthritis and Inadequate Response to Anti-TNFα Agents.
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Secukinumab (AIN457)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of Intravenous RPX2014 and RPX7009 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Bacterial Infections
Interventions: DRUG: RPX7009|DRUG: RPX2014|DRUG: Placebo|DRUG: Combination RPX7009 and RPX2014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KF2022#3-trial: Effect of Tea and Cola Beverage on Absorption of Risperidone Oral Solution
Status: RECRUITING
Conditions: Psychosis|Food-drug Interaction
Interventions: DRUG: Risperidone oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Social Learning and Course Delivery Timing in Internet-delivered Cognitive Behaviour Therapy for Public Safety Personnel
Status: RECRUITING
Conditions: Depression|Anxiety|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Tunneled Delivery|BEHAVIORAL: Personalized Delivery|BEHAVIORAL: Standard Resources|BEHAVIORAL: Enhanced Social Learning Resources|BEHAVIORAL: Transdiagnostic Self-Guided ICBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study of Different Strengths of Spinosad Topical Creme in Subjects With Pediculosis Capitis
Status: COMPLETED
Conditions: Pediculosis Capitis (Head Lice)
Interventions: DRUG: Spinosad Creme Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Low Glycaemic Index (GI) Biscuits on Postprandial Glycaemia Using the Continuous Glucose Monitoring System (CGMS™) (Biscuit Study (BIS) Study)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes
Interventions: OTHER: Biscuit 1 Control|OTHER: Biscuit 2 Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: L-arginine add-on Therapy in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: L-Arginine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: Placebo|DRUG: Solabegron (GW427353)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Whole Brain Radiation Therapy and Capecitabine in Breast Cancer Participants With Newly Diagnosed Brain Metastasis
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: WBRT|DRUG: Capecitabine|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy for Human Papillomavirus Clearance in Biopsy-confirmed Cervical Low-grade Squamous Intraepithelial Lesions
Status: TERMINATED
Conditions: Human Papillomavirus Clearance at 12 Months
Interventions: PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of AK159 in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: AK159|DRUG: MN-10-T|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacodynamic Study Comparing Prasugrel Versus Ticagrelor in Patients Undergoing PCI With CYP2C19 Loss-of-function:
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balloon Elution and Late Loss Optimization (BELLO) Study
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: IN.PACT Falcon paclitaxel eluting balloon (Drug eluting balloon)|DEVICE: Taxus (Paclitaxel eluting stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|HER2 Gene Mutation|HER-2 Gene Amplification|HER2 Positive Gastric Cancer|Salivary Gland Cancer|Salivary Gland Tumor|Salivary Gland Carcinoma|Salivary Gland Neoplasms|Lung Cancer|Colo-rectal Cancer|Rare Diseases|Solid Tumor|Recurrent Gastric Cancer|Recurrent Colon Cancer|Recurrent Breast Cancer|Head and Neck Cancer|Head and Neck Carcinoma|Bladder Cancer|Cervical Cancer|Liver Cancer|Bile Duct Cancer|Urologic Cancer|Pancreatic Cancer|Prostate Cancer|Recurrent Prostate Cancer|Rectal Cancer|Recurrent Ovarian Carcinoma|Recurrent Renal Cell Cancer|Rectal Cancer Stage II|Rectal Cancer Stage I|Rectal Cancer Stage III|Skin Cancer|Mouth Cancer|Lip Cancer Stage I|Tongue Cancer|Breast Neoplasm Malignant Primary|Larynx Cancer|Tonsil Cancer|Palate Cancer|Mucoepidermoid Carcinoma|Primary Peritoneal Carcinoma|Mucinous Adenocarcinoma Gastric|Mucinous Breast Cancer Recurrent|Cholangiocarcinoma
Interventions: DRUG: A166
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Glimepiride|DRUG: glyburide|OTHER: glucose clamp|OTHER: glucose clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Blinatumomab and Pembrolizumab for Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia With High Marrow Lymphoblasts
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Acute Lymphoblastic Leukemia, Adult
Interventions: DRUG: blinatumomab|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Robotic Assistance Module Against Positive and Negative Obstacles for Driving Electric Wheelchair
Status: COMPLETED
Conditions: Neurological Disorder
Interventions: DEVICE: Electric wheelchair with activated assistance module|DEVICE: Electric wheelchair with assistance module not activated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Can Value Champions Reduce Inappropriate Prescribing for People With Dementia?
Status: COMPLETED
Conditions: Dementia|Med: Dementia
Interventions: BEHAVIORAL: Value Champion Training Program|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cisplatin and Gemcitabine Chemotherapy and Lenvatinib for Patients With Unresectable Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: GC combined Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHAT Life: Peer Versus Adult-Led HIV Prevention for Juvenile Offenders
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: PHAT Life: Preventing HIV/AIDS Among Teens--PS Arm|BEHAVIORAL: PHAT Life: Preventing HIV/AIDS Among Teens--YR Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virus as Treatment of C. Difficile Infection (VISION)
Status: NOT_YET_RECRUITING
Conditions: Clostridium Difficile Infections
Interventions: OTHER: Fecal Virome Transplantation|OTHER: Fecal microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacroiliac Joint Fusion Comparison Study
Status: WITHDRAWN
Conditions: Sacroiliac Joint Somatic Dysfunction|Sacroiliac; Spondylitis
Interventions: PROCEDURE: Sacroiliac joint fusion|PROCEDURE: Sacroiliac joint radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
Status: RECRUITING
Conditions: Estrogen Receptor Negative|HER2 Positive Breast Carcinoma|HER2/Neu Negative|Invasive Breast Carcinoma|Progesterone Receptor Negative|Stage I Breast Cancer AJCC v7|Stage IA Breast Cancer AJCC v7|Stage IB Breast Cancer AJCC v7|Stage II Breast Cancer AJCC v6 and v7|Stage IIA Breast Cancer AJCC v6 and v7|Stage IIB Breast Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma
Interventions: RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Whole Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Keyhole Surgery for the Positioning of the Distal Catheter in Ventricular Peritoneal Shunt Placement
Status: COMPLETED
Conditions: Ventricular Peritoneal Shunt|Shunt Complications|Shunt Failure|Randomized Controlled Trial
Interventions: PROCEDURE: VP Shunt Surgery for laparoscopic insertion of the peritoneal catheter|PROCEDURE: VP Shunt Surgery for open insertion of the peritoneal catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of BPDO-1603 or BPDO-16031 and BPDO-16033 Administration in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BPDO-1603
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Behavioral Economic Intervention to Reduce Antibiotic Prescription for Upper Respiratory Infections
Status: COMPLETED
Conditions: Antibiotics|Upper Respiratory Infections|Safety-Net Hospitals|Behavioral Economics|Choosing Wisely
Interventions: BEHAVIORAL: Nudge using Behavioral Economic Interventions|BEHAVIORAL: Standard Practices to Reduce Health System Antibiotic Prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison Between Costoclavicular and Paracoracoid Ultrasound-guided Infraclavicular Block for Forearm Surgery
Status: UNKNOWN
Conditions: Brachial Plexus Block
Interventions: PROCEDURE: costoclavicular infraclavicular block|PROCEDURE: paracoracoid infraclavicular block|DEVICE: Ultrasound|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Modified Probe Tip Design on Patient Perception of Discomfort on Probing and Clinical Parameters Using the Florida Probe® System
Status: COMPLETED
Conditions: Periodontitis|Diagnoses Disease
Interventions: DEVICE: Florida Probe Straight Tip Probe|DEVICE: Ball Tip Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Myofascial Release and TENS Over Pain, Hand Prehensile Strength and Functionality of Superior Extremity in Women With Lateral Epicondylalgia
Status: COMPLETED
Conditions: Musculoskeletal Manipulations
Interventions: OTHER: TENS|OTHER: Myofascial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Belief Model-Based Educational Intervention on Safe Pesticide Use and Biomarkers in Agricultural Workers
Status: ACTIVE_NOT_RECRUITING
Conditions: Exposure Occupational|Safety Issues|Health Behavior|Nurse's Role
Interventions: BEHAVIORAL: HeBSaPU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CC-4047 With Gemcitabine for Untreated Advanced Carcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Pomalidomide|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Dose Study of Intravenous BNZ132-1-40 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Safety and Tolerability in Healthy Subjects
Interventions: DRUG: BNZ132-1-40|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting (CINV)
Interventions: DRUG: Netupitant|DRUG: Palonosetron|DRUG: Netupitant|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Intravenous Paracetamol vs. Placebo in Patients Receiving Radiofrequency Ablation of the Medial Branch Facet Nerve
Status: UNKNOWN
Conditions: Chronic Lower Back Pain|Lumbar Facet Syndrome
Interventions: DRUG: Paracetamol|DRUG: Placebo - Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Value of 18F-FES-PET/CT in Predicting Fulvestrant Efficacy in Breast Cancer
Status: UNKNOWN
Conditions: Estrogen Receptor-positive Breast Cancer|Fulvestrant
Interventions: DEVICE: 18F-FES-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: In-Vivo Evaluation of Nebulized Aerosols Delivered Via Nasal Route
Status: COMPLETED
Conditions: Interface Acceptance During Delivery of Aerosol Medicine to an Infant or Child
Interventions: BEHAVIORAL: inhaled normal saline using different interfaces.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Nutrition and Physical Activity Intervention on Psychosocial Well-Being of Postpartum Mothers
Status: COMPLETED
Conditions: Postpartum Depression|Lifestyle, Healthy
Interventions: BEHAVIORAL: Mommies can Eat & Exercise with No Stress (MomEENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
Status: COMPLETED
Conditions: Unfavorable Cervix, Cervical Ripening
Interventions: DEVICE: Foley catheter|DRUG: PGE2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Gleevec and Taxotere as a Combined Regimen for Advanced Gastric Adenocarcinoma
Status: TERMINATED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Gleevec, Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcutaneous Electrical Nerve Stimulation on Quadriceps Central Activation and Gait
Status: COMPLETED
Conditions: Tibial Femoral Knee Osteoarthritis|Osteoarthritis
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|DEVICE: Placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)|Immune Thrombocytopenic Purpura (ITP)|Kawasaki Syndrome
Interventions: BIOLOGICAL: Immune Globulin Intravenous (Human), 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction Training (BFR) in an Adolescent Population
Status: COMPLETED
Conditions: Blood Flow Restriction|ACL Tear|ACL Injury
Interventions: DEVICE: Blood Flow Restriction using Delfi Personalized Tourniquet System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rubber Band Ligation and Mucosectomy for Gastroesophageal Reflux Disease (GERD)
Status: TERMINATED
Conditions: Gastroesophageal Reflux Disease|Heartburn|Regurgitation|Dyspepsia
Interventions: PROCEDURE: Mucosectomy|PROCEDURE: Rubber Band Ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SBRT (Stereotactic Body Radiation Therapy) in Combination With Nivolumab/Ipilimumab in Renal Cell Carcinoma (RCC) / Kidney Cancer Patients
Status: COMPLETED
Conditions: Kidney Cancer Metastatic|Kidney Cancer|Kidney Cancer, Stage IV
Interventions: DRUG: Nivolumab/Ipilimumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Breast Cancer Progressing After First-Line Therapy With Avastin and Chemotherapy (TANIA)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Naltrexone-Bupropion (NB) Combination|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04965842|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed.
Status: TERMINATED
Conditions: Upper Gastrointestinal Bleeding
Interventions: DRUG: Erythromycin|DRUG: Metoclopromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Vardenafil in Subjects With Erectile Dysfunction (ED) Administered 12, 18 or 24 Hours Prior to Intercourse
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Stage IIIB/IV|Non-small Cell Lung Cancer Metastatic|Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: DRUG: metformin|BEHAVIORAL: carbohydrate restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Irinotecan in Treating Patients With Stage III Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)
Status: COMPLETED
Conditions: Central Nervous System Diseases
Interventions: DRUG: Memantine Tab. 10mg|DRUG: Memantine Tab. 10mg + Donepezil Tab. 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Geriatric Assessment in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Comprehensive geriatric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal Block Versus Serratus Anterior Plane Block
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: general anesthesia|PROCEDURE: general anesthesia plus Rhomboid intercostal block|PROCEDURE: Serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Geographic Atrophy
Interventions: DRUG: Lampalizumab|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ICP-022 in Patients With R/R Mantle Cell Lymphoma (MCL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: ICP-022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Borrelia Bacteria in Early Stage Lyme Borreliosis Using the T2Lyme Panel
Status: TERMINATED
Conditions: Lyme Disease
Interventions: DEVICE: T2Lyme Panel testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: systemic chemotherapy|OTHER: laboratory biomarker analysis|PROCEDURE: therapeutic surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of a Catheter-based Ultrasound Hyperthermia System
Status: TERMINATED
Conditions: Cervical Cancer|Prostate Cancer
Interventions: PROCEDURE: Hyperthermia|RADIATION: HDR brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: PhosphoRus, Proton Imaging and Amyloid BuRdEn (PREPARE) ON AMYLOID BURDEN AND COGNITION
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: Measure of OxPhos upregulation|DIAGNOSTIC_TEST: lactate (measured with 1H-MRSI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerability/Safety of Intranasal AZD8848 in Healthy Male Volunteers and Seasonal Allergic Rhinitis Male Patients Out of Season
Status: COMPLETED
Conditions: Healthy|Allergic Rhinitis
Interventions: DRUG: AZD8848|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs
Status: RECRUITING
Conditions: Metopic Synostosis
Interventions: PROCEDURE: craniofacial surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Cardiac Arrest
Interventions: BEHAVIORAL: chest compression with kneeling position|BEHAVIORAL: chest compression with standing position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rasburicase as a Uricolytic Therapy for Hyperuricemia in Patients With Leukemia or Lymphoma
Status: COMPLETED
Conditions: Hyperuricemia|Leukemia|Lymphoma
Interventions: DRUG: Rasburicase (SR29142)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Anesthesia and Postoperative BIS in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Remifentanil|DRUG: sevoflurane and sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Pegylated Interferon Alfa-2A in Combination With Lamivudine or Entecavir Compared With Untreated Control Group in Children With Hepatitis B Envelope Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) in the Immune-Tolerant Phase
Status: COMPLETED
Conditions: Pediatric Immuno-Tolerant Chronic Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Lamivudine|DRUG: Pegylated Interferon Alfa-2A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 11C-5-HTP PET in Clinical Islet Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Positron-Emission Tomography|BIOLOGICAL: 11C-5-HTP|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Mixed-Meal Tolerance Test (MMTT)|PROCEDURE: Continuous Glucose Monitoring System® (CGMS)|PROCEDURE: Glomerular Filtration Rate Testing|PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD With Extra (Pulse) Dose on Day of Surgery for Treatment of Ocular Inflammation Associated With Cataract Surgery in a Randomized, Single Masked Clinical Trial
Status: COMPLETED
Conditions: Treatment of Ocular Inflammation Associated With Cataract Surgery
Interventions: DRUG: Bromfenac|DRUG: Nepafenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adriamycin, Vinblastine, DTIC and Revlimid in Elderly Hodgkin Lymphoma Patients
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Doxorubicine|DRUG: DTIC|DRUG: Lenalidomide|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Naltrexone In Pediatric Eating Disorders
Status: TERMINATED
Conditions: Anorexia Nervosa/Bulimia|Anorexia in Adolescence|Anorexia Nervosa, Atypical|Anorexia Nervosa, Binge Eating/Purging Type|Purging (Eating Disorders)|Impulsive Behavior|Eating Disorders|Bulimia Nervosa|Eating Disorders in Adolescence
Interventions: DRUG: Naltrexone Hydrochloride|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Pediatric Subjects
Status: NOT_YET_RECRUITING
Conditions: Sialorrhea
Interventions: DRUG: MYOBLOC Low Dose|DRUG: MYOBLOC High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Study of Domestic Recombinant Human Follitropin for Injection to Treat WHO Class II Anovulation
Status: COMPLETED
Conditions: Anovulation
Interventions: BIOLOGICAL: Gonal-F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiological Results of Conservative Treatments in Proximal Humerus Fractures.
Status: COMPLETED
Conditions: Proximal Humeral Fracture
Interventions: DEVICE: Shoulder arm bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ASF1057 in the Treatment of Seborrhoeic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: ASF1057|DRUG: ASF1057
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Polystyrene Microplastics on Anxiety- and Depression-like Behaviors
Status: COMPLETED
Conditions: Depression, Anxiety
Interventions: OTHER: Dietary polystyrene microplastics from disposable plastic tableware
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancer
Status: COMPLETED
Conditions: Sarcoma|Wilm's Tumor|Lymphoma|Neuroblastoma
Interventions: DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: bLAC - Treatment of Cutaneous Warts in Immune Suppressed, Kidney Transplanted Patients
Status: UNKNOWN
Conditions: Cutaneous Warts
Interventions: DRUG: bLAC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect on the QT/QTc Interval of Repeated and Escalating Doses of AZD3480 During 6 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD3480|DRUG: Moxifloxacin|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)
Status: RECRUITING
Conditions: Severe Asthma
Interventions: DRUG: Verekitug (UPB-101)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 4 or 5 HCV Infection
Status: COMPLETED
Conditions: Chronic Genotype 4 HCV|Chronic Genotype 5 HCV
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Standard of care ADT + (HMB + arginine + glutamine)|OTHER: Standard of care ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study of Two Continuous Regimens of Oral Daily 5 mg or 10 mg of Ulipristal Acetate (UPA), Versus a Dose of 5.0mg UPA for 24/4 Days
Status: COMPLETED
Conditions: Focus: Estrogen-free Oral Contraception
Interventions: DRUG: Ulipristal Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant HAIC for Resectable Hepatocellular Carcinoma Beyond Milan Criteria
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: FOLFOX|PROCEDURE: Hepatic resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Analyze the Effect of Acupuncture on Mobility And Quality of Life in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Standard of Care with no acupuncture|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: oral levofloxacin|DRUG: nebulized levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tooth Sensitivity Relief by Two Mouthrinses
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DEVICE: 12027-019|DEVICE: 12027-020|DEVICE: 12027-021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Diaphragmatic Paralysis|Anterior Suprascapular Nerve Block|Superficial Cervical Plexus Block|Phrenic Nerve Paralysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Epidemiology and Optimal Treatment of Helicobacter Pylori in Myanmar
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Clarithromycin 500mg|DRUG: Amoxicillin 500mg|DRUG: Tinidazole 500mg|DRUG: Rabeprazole 20mg|DRUG: Clarithromycin 500mg|DRUG: Amoxicillin 500mg|DRUG: Tinidazole 500mg|DRUG: Rabeprazole 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety in Moderately Active Refractory Ulcerative Colitis Patients
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: KRP203|DRUG: Placebo matching KRP203
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)
Status: ENROLLING_BY_INVITATION
Conditions: Substance-Related Disorders|Recidivism|Opioid-Related Disorders|Substance Use|Criminal Behavior
Interventions: OTHER: Learning Health System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Lived Experiences Measured Using Rings Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Stress|Sleep|Anxiety
Interventions: BEHAVIORAL: Moodlifters|BEHAVIORAL: Physical Activity|BEHAVIORAL: Nature Experiences
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Intravenous Exenatide on Cardiac Repolarization
Status: COMPLETED
Conditions: Healthy Adult Male and Female Volunteers
Interventions: DRUG: Exenatide|DRUG: Placebo|DRUG: Moxifloxacin|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: remazolam|DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Hypothermia Control In Older Patients With Total Knee Arthroplasty: Effect Of Electric And Woolen Blanket
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: electric blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dual-Polymer Hydroxypropyl Guar-and Hyaluronic Acid Lubricants in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Dry Eye Syndromes
Interventions: DRUG: SYSTANE™ Hydration Lubricant Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Urine Composition Saturation and Dietary Intervention in Subjects Without Urinary Calculi
Status: ACTIVE_NOT_RECRUITING
Conditions: Calculi, Urinary|Dietary Supplements|Urine Specimen Collection
Interventions: DIETARY_SUPPLEMENT: Giving subjects different phosphorus diets at different stages of the trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Lung Diseases
Interventions: PROCEDURE: Low Tidal Volume Ventilation|PROCEDURE: Positive End-Expiratory Pressure|DRUG: Lysofylline|DRUG: Methylprednisolone|DRUG: Ketoconazole|PROCEDURE: Fluid Management|PROCEDURE: Pulmonary Artery Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Ketamine Versus Neostigmine as Adjuvants to Bupivacaine During Ultrasound-guided Serratus Anterior Block
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Adjuvants, Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke
Status: RECRUITING
Conditions: Complex Regional Pain Syndromes
Interventions: DEVICE: The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK)|DEVICE: Sham transcranial magnetic stimulation|DEVICE: conventional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gelesis100 on Body Weight in Overweight and Obese Subjects With and Without Type 2 Diabetes
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DEVICE: Gelesis100|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Infection in Obese Women After Cesarean Delivery
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Absorbable suture group|PROCEDURE: Non absorbable suture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Remote Interpreter Modalities in the Pediatric Emergency Department
Status: COMPLETED
Conditions: Limited English Proficient Patients and Families
Interventions: OTHER: Telephone Interpretation|OTHER: Video Interpretation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Bleaching Induced Sensitivity
Status: COMPLETED
Conditions: Tooth Bleaching|Tooth Sensitivity
Interventions: OTHER: neutral sodium fluoride|OTHER: ACP-CCP gel|OTHER: nano-hydroxyapatite solution|OTHER: glycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Versus Deferred Ureteroscopy for Calculus Anuria in Children
Status: UNKNOWN
Conditions: Ureter Obstruction
Interventions: PROCEDURE: Primary ureterscopy URS|PROCEDURE: deferred ureteroscopy URS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: F-18 Fluorodeoxyglucose|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: prednisone|DRUG: sirolimus|DRUG: tacrolimus|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation|DRUG: Filgrastim|PROCEDURE: Peripheral Blood Stem Cell donation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation Comparing Regional Distribution of Ventilation During Lung Expansion Therapy
Status: COMPLETED
Conditions: Ventilation|Breathing|Atelectasis
Interventions: DEVICE: Volumetric Incentive Spirometry|DEVICE: EzPAP® POSITIVE AIRWAY PRESSURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH