pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: CXCR1/2 Inhibitor SX-682|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Training With antiGRAVIty TREadmill 'Alter-G', in Patients With ParkinSON Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: AlterG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Celecoxib Suspension Compared to Naproxen Suspension in Patients With JRA
Status: COMPLETED
Conditions: Arthritis, Juvenile Rheumatoid
Interventions: DRUG: Celecoxib|DRUG: Celecoxib|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura: Multicentric Non-inferiority Single-arm Study
Status: NOT_YET_RECRUITING
Conditions: Thrombotic Microangiopathies
Interventions: PROCEDURE: PEX-FREE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Serious Adverse Events in Acute Care Hospitals by Afferent Limb and Response Method Intervention - the ALARM Intervention Study.
Status: COMPLETED
Conditions: Unexpected Hospital Mortality|Death, Sudden, Cardiac|Unplanned Intensive Care Unit Admission
Interventions: OTHER: ALARM intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain
Status: UNKNOWN
Conditions: Hip Pain Chronic|Knee Pain Chronic
Interventions: DIETARY_SUPPLEMENT: High Oleic Sunflower Oil|DIETARY_SUPPLEMENT: Buglossoides Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Stage III or Stage IV Melanoma
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: dendritic cell-gp100-MART-1 antigen vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency
Status: COMPLETED
Conditions: Lysosomal Acid Lipase Deficiency|Wolman Disease
Interventions: DRUG: Sebelipase alfa (SBC-102)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease
Status: COMPLETED
Conditions: Hyperphosphatemia|End-Stage Renal Disease
Interventions: DRUG: ferric citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of The Effect of Web-Based System With Oculomotor and Optokinetic Stimulation on Rehabilitation in Vestibular Hypofunction
Status: COMPLETED
Conditions: Vestibular Rehabilitation|Vestibular Disease
Interventions: OTHER: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction
Status: UNKNOWN
Conditions: Rhinitis|Sinusitis
Interventions: DRUG: Luffa Operculate Nasal Solution 5mg/mL|DRUG: Saline Solution (NaCl 0,9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block vs Erector Spinae Plane Block in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Gynecologic Disease
Interventions: PROCEDURE: Quadratus Lumborum Block Type III|PROCEDURE: Erector Spinae Plane Block|OTHER: No Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate for Immune Related Arthritis or Arthralgias (IMPACT 2.1)
Status: NOT_YET_RECRUITING
Conditions: Arthritis|Arthralgia
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0106A, Biomarkers in Samples From Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Cytarabine-Based Chemotherapy
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: proteomic profiling|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Phase I Study on GIC-1001 in Healthy Volunteers
Status: COMPLETED
Conditions: Colonic Diseases
Interventions: DRUG: GIC-1001; 125 mg oral tablets|DRUG: GIC-1001 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VP-16, Ifosfamide, Dexamethasone, L-asparaginase Chemotherapy in Patients With Extranodal Natural Killer T Cell Lymphoma (VIDL+ASCT)
Status: UNKNOWN
Conditions: Extranodal NK-T-Cell Lymphoma
Interventions: DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Dexamethasone|DRUG: L-asparaginase|DRUG: Busulfan|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VX-950-TiDP24-C124: A Phase I Trial to Investigate the Potential Pharmacokinetic Interactions Between Telaprevir and Darunavir/Ritonavir and Between Telaprevir and Fosamprenavir/Ritonavir at Steady-state.
Status: COMPLETED
Conditions: Hepatitis C|Telaprevir|HIV
Interventions: DRUG: Telaprevir; Darunavir; Ritonavir; Fosamprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritoneal Iliac Flap and Lymphocele Formation After Robotic Radical Prostatectomy
Status: COMPLETED
Conditions: Lymphocele After Surgical Procedure
Interventions: PROCEDURE: lymph node dissection using the peritoneal iliac flap approach to seal lymphatic vessels|PROCEDURE: Standard surgical approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Acceptability of Mobile Mental Health App for SZ and SZA
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: BEHAVIORAL: Intervention via mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy and Safety of Hetrombopag as Secondary Prevention to Chemotherapy-induced Thrombocytopenia in Patients With Gynecologic Malignancies
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-induced Thrombocytopenia
Interventions: DRUG: Hetrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Tumor-Infiltrating Lymphocyte (GTE-001 Injection ) for Treatment of Patients With Advanced Lung Adenocarcinoma
Status: RECRUITING
Conditions: Advanced Lung Adenocarcinoma；Adult
Interventions: BIOLOGICAL: GTE001 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study
Status: COMPLETED
Conditions: Advanced Pancreatic Carcinoma|Locally Advanced Pancreatic Carcinoma|Metastatic Pancreatic Carcinoma|Pancreatic Neoplasm|Stage II Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Pancreatic Carcinoma
Interventions: PROCEDURE: Endoscopic Ultrasound|PROCEDURE: Fluorescence Imaging|DRUG: Photodynamic Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Endothelial Function
Status: COMPLETED
Conditions: Endothelial Dysfunction|Atherosclerosis
Interventions: DRUG: Rosuvastatin 5mg/day|DRUG: Rosuvastatin 40mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Evaluate the Clinical Performance and Safety of the SIRIUS Endoscope System in Laparoscopic Gynecological Surgery.
Status: ENROLLING_BY_INVITATION
Conditions: Ovarian Cancer|Cervical Cancer|Gynecologic Cancer
Interventions: DEVICE: Gynaecological laparoscopic surgery (Sirius System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Immunogenicity of an Investigational RSV Vaccine Candidate (Ad26.RSV.preF) in Adults 18 to 50 Years of Age, and RSV-seropositive Toddlers 12 to 24 Months of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Viruses|Respiratory Tract Infections
Interventions: BIOLOGICAL: Ad26.RSV.preF (1*10^11 vp)|BIOLOGICAL: Ad26.RSV.preF (5*10^10 vp)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase I/II Trial of PTK787 and Pemetrexed With or Without Cisplatin for Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer and Pleural Mesothelioma
Interventions: DRUG: PTK787 and Pemetrexed with or without Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abdominal Massage in Enteral Nutrition Patients
Status: NOT_YET_RECRUITING
Conditions: Enteral Nutrition|Gastrointestinal System--Abnormalities
Interventions: OTHER: Nutrition of Continuous|OTHER: Nutrition of Bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Traditional Dietary Advice Versus a Low FODMAP Diet Intake in IBS Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Diet A i.e. Low FODMAP diet|BEHAVIORAL: Diet B, i.e. Traditional IBS diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intron-A/Aldara Combination Therapy for Basal Cell Carcinoma (BCC)
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: BIOLOGICAL: Imiquimod and Interferon alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Asymmetry in Progressive Multiple Sclerosis Patients
Status: RECRUITING
Conditions: Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Secondary Progressive
Interventions: RADIATION: Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Neurological examination|DIAGNOSTIC_TEST: Multiple Sclerosis Functional Composite|DIAGNOSTIC_TEST: Physiotherapist examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: KN046 (a Humanized PD-L1/CTLA4 Bispecific Single Domain Fc Fusion Protein Antibody) in Subjects With Thymic Carcinoma
Status: TERMINATED
Conditions: Thymic Carcinoma
Interventions: DRUG: KN046
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Marginal B. Loss in Immediate Implant Placement in Maxillary Esthetic Zone Using Socket Shield Versus Xenograft
Status: UNKNOWN
Conditions: Marginal Bone Loss in Socket Shield Technique
Interventions: PROCEDURE: Socket shield technique|PROCEDURE: using Xenograft material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Dosimetry for Prostate Brachytherapy Using Fluoroscopy and Ultrasound
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: RADIATION: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms|Endoscopy|Biopsy|Pathology
Interventions: DEVICE: endoscopy|PROCEDURE: Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 11C-Trimethoprim PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Bacterial Infections
Interventions: DRUG: 11C-Trimethoprim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.
Status: COMPLETED
Conditions: Fetal Distress|Stillbirth|Birth Asphyxia|Acidosis
Interventions: PROCEDURE: Fetal Scalp Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Myo-kinetic Stretching Versus Post-isometrics Relaxation Exercise With Traction in Patients of Cervical Radiculopathy
Status: RECRUITING
Conditions: Cervical Radiculopathy
Interventions: OTHER: Myokinetic stretching technique|OTHER: Post Isometric Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Salvage Treatment With Combination of Docetaxel and Epirubicin
Status: COMPLETED
Conditions: Metastatic Advanced Gastric Cancer
Interventions: OTHER: Docetaxel 60 mg/m2, epirubicin 60 mg/m2, q3wks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Study of Sativex in Multiple Sclerosis (MS) Spasticity
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Sativex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DOM-INNATE: Study of SGX942 for the Treatment of Oral Mucositis in Patients With Concomitant Chemoradiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Oral Cavity and Oropharynx|Oral Mucositis
Interventions: DRUG: SGX942|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Nutrition Therapy and Diabetes Self-Management Education for People With Disabilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Physical Disability
Interventions: BEHAVIORAL: High-Tech|BEHAVIORAL: Low-Tech|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Drug-drug Interaction Study to Investigate the Effects of AZD1981 on the Metabolism and Pharmacodynamics of Oral Contraceptives
Status: COMPLETED
Conditions: Oral Contraceptives
Interventions: DRUG: AZD1981|DRUG: Neovletta 21/28|DRUG: Placebo AZD1981
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Noninvasive NAVA Versus NIPPV in Low Birthweight Premature Infants
Status: TERMINATED
Conditions: Noninvasive Ventilation|Low Birth Weight
Interventions: DEVICE: Neurally Adjusted Ventilatory Assist|DEVICE: Nasal Intermittent Positive Pressure Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)
Status: RECRUITING
Conditions: Frontotemporal Dementia
Interventions: BIOLOGICAL: LY3884963|DRUG: Methylprednisolone|DRUG: Optional Sirolimus|DRUG: Optional Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Open Label Phase II Study of Pomalidomide and Cyclophosphamide and Dexamethasone in Relapse/Refractory Multiple Myeloma Patients Who Were First Treated Within the IFM/DFCI 2009 Trial
Status: COMPLETED
Conditions: Multiple Myeloma|First Relapse
Interventions: DRUG: PCD|PROCEDURE: Autologous transplantation (ASCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial: The Efficacy of Janssen's Icon Application (App) in Improving Adherence to Treatment With Stimulant Medications in Children With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Children Aged 6-18 Years With the Diagnosis of ADHD
Interventions: DEVICE: Janssen's icon Application (App)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Gel and Epidermal Regeneration in Healthy Human Volunteers
Status: UNKNOWN
Conditions: Denuded Epidermis
Interventions: OTHER: Shower gel with zinc|OTHER: Plain shower gel|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, PK and PD of Kamada Anti-SARS-CoV-2 in COVID-19
Status: COMPLETED
Conditions: Covid19|Pneumonia, Viral
Interventions: BIOLOGICAL: Kamada Anti-SARS-CoV-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Status: WITHDRAWN
Conditions: Scleroderma
Interventions: DRUG: BMS-986020|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Booster Dose of the SpikoGen COVID-19 Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 recombinant spike protein + Advax-SM adjuvant|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Better Lifestyle Counseling for African American Women During Pregnancy
Status: RECRUITING
Conditions: Overweight or Obesity|Pregnancy Related|Sleep Disturbances|Sleep Hygiene|Pregnancy Complications|Diversity|Stress, Psychological|Fitness Trackers|Exercise|African Americans|Disparities in Pregnancy Complications|Sleep Disparities
Interventions: BEHAVIORAL: Better|BEHAVIORAL: Birth Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Squamous Cell Carcinoma of Head and Neck|Prostate Cancer|Ewing's Osteosarcoma|Chronic Lymphocytic Leukemia|Neoplasm Metastasis
Interventions: DRUG: CC-115
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Triheptanoin for People With Amyotrophic Lateral Sclerosis (PALS)
Status: COMPLETED
Conditions: ALS
Interventions: DRUG: Triheptanoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Pre-diabetes
Interventions: OTHER: Lifestyle intervention (cold exposure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-374 5 mg in Healthy Volunteers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: D569 Tab.|DRUG: CKD-374 5mg Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platelet Rich Plasma for Treatment of Muscle Rupture With Haematoma
Status: COMPLETED
Conditions: Muscle Injuries
Interventions: BIOLOGICAL: Autologous Platelet-rich plasma (PRP)|PROCEDURE: Evacuation of haematoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Continuous and Interval Physical Training Through the Intensity of the Incremental Shuttle Walk Test, on Functional Capacity and Quality of Life in Women With Malignant Breast Cancer During Chemotherapy Treatment
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Female|Exercise Addiction
Interventions: OTHER: Rehabilitation, exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Study Of Tanezumab Subcutaneous Administration In Osteoarthritis - A Subcutaneous/Intravenous Bridging Study
Status: TERMINATED
Conditions: Osteoarthritis|Arthritis|Pain
Interventions: BIOLOGICAL: Placebo IV|BIOLOGICAL: Placebo SC|BIOLOGICAL: Tanezumab SC|BIOLOGICAL: Placebo IV|BIOLOGICAL: Tanezumab SC|BIOLOGICAL: Placebo IV|BIOLOGICAL: Tanezumab SC|BIOLOGICAL: Placebo IV|BIOLOGICAL: Tanezumab IV|BIOLOGICAL: Placebo SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of External Electrical Stimulation and Pelvic Floor Muscle Training
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Electrical Stimulation|Pelvic Floor Disorders|Urinary Incontinence
Interventions: BEHAVIORAL: External electrical stimulation (EES) added to pelvic floor muscle training (PFMT)|BEHAVIORAL: External electrical stimulation|BEHAVIORAL: Pelvic floor muscle training (PFMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Study Between Diminished and Normal Responder in IVF
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Melatonin adminstration|DRUG: placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Evaluation of the Ivory Dentin Graft Device (IvoryGraft) - Long Term Follow-Up
Status: ACTIVE_NOT_RECRUITING
Conditions: Deficiency of Alveolar Ridge (Disorder)|Alveolar Bone Grafting|Mandibular Prosthesis User
Interventions: DEVICE: Ivory Dentin Graft|DEVICE: OsteoBiol Gen-Os
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers
Status: COMPLETED
Conditions: Insomnia|Related Distress Among Cancer Caregivers
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|PROCEDURE: Acupuncture|BEHAVIORAL: questionnaires|OTHER: Diurnal Cortisol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Healing Process of Idiopathic Macular Hole With Different Surgical Techniques
Status: UNKNOWN
Conditions: Macular Holes
Interventions: PROCEDURE: Conventional ILM Peeling|PROCEDURE: Inverted ILM Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate and Prednisone With or Without Dasatinib in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: UNKNOWN
Conditions: Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: abiraterone acetate|DRUG: dasatinib|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Coronary In-Stent Restenosis
Status: COMPLETED
Conditions: Restenosis
Interventions: DEVICE: paclitaxel-coated balloon catheter with Iopromide coating|DEVICE: drug eluting stent with everolimus|DEVICE: seal-wing paclitaxel-eluting balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing Strategies to Optimize the Exercise Response After Tetraplegia.
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Spinal Cord Injury Cervical|Paraplegia, Spinal
Interventions: BEHAVIORAL: HITT: intermittent high intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of Adherence to Methylprednisolone Aceponate in Different Carriers
Status: COMPLETED
Conditions: Adherence, Patient|Chronic Eczema
Interventions: BEHAVIORAL: Adherence to topical standard therapy assessed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maxillary Canine Retraction Assisted With Micro-osteoperforations Versus Injectable Platelet Rich Fibrin
Status: ENROLLING_BY_INVITATION
Conditions: Effects of; Movement of Teeth Assiste Wit MOPS and I-prf
Interventions: COMBINATION_PRODUCT: injectable platelet rich fibrin versus microosteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment With Peripheral Nerve Stimulation of the Pudendal Nerve in Patients With Erectile Dysfunction
Status: ACTIVE_NOT_RECRUITING
Conditions: Erectile Dysfunction|Electric Stimulation|Pudendal Nerve
Interventions: OTHER: Percutaneous electrical neurostimulation (Placebo)|OTHER: Percutaneous electrical neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: N-803 and BCG|DRUG: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS and Rehabilitation for Individuals With CRPS Type 1
Status: RECRUITING
Conditions: Complex Regional Pain Syndrome Type I
Interventions: DEVICE: Repeated Transcranial Magnetic Stimulation|DEVICE: Sham Repeated Transcranial Magnetic Stimulation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPSITE Post-Op Visible Wound Dressings in Treatment of Surgical Incisions
Status: COMPLETED
Conditions: Patients Undergoing Clean Surgery
Interventions: DEVICE: OPSITE POST-OP VISIBLE|DEVICE: Tape and Gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-MARVEL - Mitochondrial Antioxidant Therapy in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: MitoQ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Tree Pollen Allergy Vaccine
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Tree MATA MPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pressure-controlled Intermittent Coronary Sinus Occlusion (PiCSO) Therapy on miRNAs Expression and Absolute Microvascular Resistance by Continuous Thermodilution in ST-segment Elevation Myocardial Infarction (STEMI) Patients: PiCSO-STEMI TRIAL
Status: NOT_YET_RECRUITING
Conditions: Anterior Myocardial Infarction
Interventions: DEVICE: PiCSO Impulse System|PROCEDURE: Percutaneous Coronary Intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: GSK3884464|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Levomilnacipran ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subclinical Joint Bleeding in Irish Adults With Severe Haemophilia A on Personalised Prophylaxis Regimens
Status: UNKNOWN
Conditions: Severe Haemophilia A
Interventions: DRUG: ADVATE [Antihemophilic Factor (Recombinant)]|DRUG: ADVATE [Antihemophilic Factor (Recombinant)]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Magnesium and Muscle Cramps in Dialysis Patients.
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|End Stage Renal Disease|Dialysis Related Complications
Interventions: DRUG: Transdermal Magnesium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Locally Advanced Lung Non-Squamous Non-Small Cell Carcinoma|Stage III Lung Adenocarcinoma AJCC v7|Stage III Lung Large Cell Carcinoma AJCC v7|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Adenocarcinoma AJCC v7|Stage IIIA Lung Large Cell Carcinoma AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Adenocarcinoma AJCC v7|Stage IIIB Lung Large Cell Carcinoma AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7|Stage IV Lung Adenocarcinoma AJCC v7|Stage IV Lung Large Cell Carcinoma AJCC v7|Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Cisplatin|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Methoxyamine|DRUG: Methoxyamine Hydrochloride|DRUG: Pemetrexed|DRUG: Pemetrexed Disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitochondrial Complex I Dysfunction in PWS
Status: WITHDRAWN
Conditions: Prader-Willi Syndrome
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Desloratadine Single Dose|DRUG: Levocetirizine Single Dose|DRUG: Desloratadine Fourfold Dose|DRUG: Levocetirizine Fourfold Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models
Status: RECRUITING
Conditions: Gastrointestinal Neoplasm Malignant
Interventions: OTHER: Clinician-Directed Treatment Plan|OTHER: ChatGPT-Assisted Treatment Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Dietary Portfolio - Intensive|DIETARY_SUPPLEMENT: Dietary Portfolio - Routine|DIETARY_SUPPLEMENT: Control (low saturated fat therapeutic diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Siltuximab for the Prevention of CAR T Cell Related Cytokine Release Syndrome in Patients With CD19 Positive Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Siltuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability, and Pk of rhMBL in Pediatric Hematology/Oncology Pts With Fever and Neutropenia
Status: WITHDRAWN
Conditions: Cancer|Hematologic Diseases|Fever|Neutropenia
Interventions: DRUG: Intravenous recombinant human mannose binding lectin|DRUG: Intravenous recombinant human mannose binding lectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Rate Adaptive Pacing on Chronotropic Response in Preserved Ejection Fraction HF
Status: WITHDRAWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DEVICE: Rate Adaptive Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CYA Versus MMF for Treatment of Moderate-Severe Psoriasis.
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Cyclosporine A versus mycophenolate mofetil for psoriasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder
Status: COMPLETED
Conditions: Suicide, Attempted|Substance-Related Disorders
Interventions: BEHAVIORAL: Cognitive Therapy|OTHER: Enriched Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Mitomycin and Aflibercept Used to Support Primary Trabeculectomy.
Status: COMPLETED
Conditions: Eye Diseases|Optic Nerve Damage|Glaucoma Surgery
Interventions: DRUG: Aflibercept|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Plyometric vs Explosive Strength Training on Agility, Power, and Balance in Basketball Players
Status: RECRUITING
Conditions: Plyometric Exercise|Resistance Training|Basketball
Interventions: OTHER: Plyometric training exercises|OTHER: Explosive strength training exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Ramucirumab in Participants With Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab|DRUG: Placebo|DRUG: S-1|DRUG: Oxaliplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Training and Soy-based Nutritional Supplementation on Prevention of Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: exercise/soy isoflavone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients
Status: TERMINATED
Conditions: Pancreatitis
Interventions: DRUG: diclofenac|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Age and Response to Flu Vaccines
Status: COMPLETED
Conditions: Influenza|Influenza Immunisation
Interventions: BIOLOGICAL: Influenza Virus Quadrivalent Inactivated Vaccine|BIOLOGICAL: Influenza Virus Quadrivalent Inactivated Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pain Management and Patient Education for Physical Activity in Intermittent Claudication (PrEPAID)
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DEVICE: Active TENS|BEHAVIORAL: Patient-Centred Education|DEVICE: Placebo TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of a Food Supplement Based on Hydrolyzed Collagen on Joint Function.
Status: RECRUITING
Conditions: Pain, Acute|Pain, Chronic|Knee Osteoarthritis|Knee Injuries
Interventions: DIETARY_SUPPLEMENT: COLLAGEN (COL)|DIETARY_SUPPLEMENT: PLACEBO (PLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The SPOT-HPV Study
Status: ACTIVE_NOT_RECRUITING
Conditions: HPV Infection|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Salivary TTMV-HPV DNA Test|DIAGNOSTIC_TEST: Blood TTMV-HPV DNA Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cricopharyngeal Dysfunction and Esophageal Diverticulum
Status: RECRUITING
Conditions: Zenker Diverticulum|Progressive Dysphagia|Pharyngoesophageal Diverticulum
Interventions: PROCEDURE: open, transcervical versus rigid endoscopic treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Efficacy and Safety Study for the Treatment of Mild to Moderate Acute Pain Associated With Ankle Strain or Sprain.
Status: TERMINATED
Conditions: Acute Pain From Ankle Sprain or Strain
Interventions: DRUG: K-103-IP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for Post-Operative Atrial Fibrillation
Status: SUSPENDED
Conditions: Atrial Fibrillation|Post-operative Atrial Fibrillation
Interventions: BIOLOGICAL: AdKCNH2-G628S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DRUG: GSK2330811|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subclinical Hypothyroidism and Normogonadotropic Anovulation
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Hypothalamic-Pituitary-Ovarian Axis Dysfunction (Disorder)
Interventions: OTHER: Comparison of laboratory test results in women in the 4 study arms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Stepped Care Versus Best Available Care for Bulimia Nervosa
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Fluoxetine|BEHAVIORAL: Guided Self-Help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low Molecular Heparin on Pregnancy Outcome With Protein S Deficiency
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Protein S Deficiency
Interventions: DRUG: Enoxaparin|DRUG: Aspirin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Castration Levels of Testosterone|Metastatic Prostatic Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Abiraterone|DRUG: Bicalutamide|DRUG: Degarelix|DRUG: Docetaxel|DRUG: Flutamide|DRUG: Goserelin Acetate|DRUG: Histrelin Acetate|DRUG: Leuprolide Acetate|DRUG: Nilutamide|PROCEDURE: Orchiectomy|DRUG: Prednisone|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|PROCEDURE: Radical Prostatectomy|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, PD, ADA of Escalating Single Dose of CJ-40002 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ-40002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine Versus Magnesium Sulphate in Patients Undergoing Craniotomy for Deeply Settled Intracranial Tumours
Status: NOT_YET_RECRUITING
Conditions: Brain Tumor
Interventions: DRUG: Dexmedetomidine|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tobacco Cessation at FDNY
Status: RECRUITING
Conditions: Tobacco Use|Tobacco Smoking|Tobacco Use Cessation
Interventions: OTHER: opt out enrollment, tailored counseling, varenicline started prior to target quit date|OTHER: opt in enrollment, non-tailored counseling, varenicline started prior to target quit date
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Metabolism of Glycolate to Oxalate
Status: RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Low oxalate controlled Diet|OTHER: Primed, continuous intravenous infusion of 13C2-Glycolate|OTHER: Bolus intravenous infusion of 13C2-Glycolate|OTHER: Oral bolus administration of 13C2-Glycolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NIV-NAVA Versus Nasal Continuous Positive Airway Pressure (nCPAP) or Non Synchronized NIPPV
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn|Apnea of Prematurity
Interventions: DEVICE: NIV-NAVA|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT