pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: High Dose Interval Vitamin D Supplementation in Patients With IBD Receiving Remicade
Status: ACTIVE_NOT_RECRUITING
Conditions: IBD|Ulcerative Colitis|Crohn Disease
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UARK 2003-41: A Study of High-Dose Density Therapy in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: High-Dose Density Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males
Status: RECRUITING
Conditions: Male Infertility
Interventions: DRUG: DLBS5055 200mg|DRUG: Placebo DLBS5055|DRUG: Multivitamin (Vitamin C 500mg + Vitamin E 100IU + Beta Carotene 10000IU)|DRUG: Placebo Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Daratumumab|PROCEDURE: autologous hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Dilator Therapy Among Women With Gynecologic and Breast Cancers Experiencing Dyspareunia
Status: WITHDRAWN
Conditions: Dyspareunia
Interventions: OTHER: Vaginal Moisturizer|DEVICE: Vaginal Dilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erlotinib in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tegafur Combined With Temozolomide Versus Tegafur Combined With Temozolomide and Thalidomide in Subjects With Advanced Extrapancreatic Neuroendocrine Tumor
Status: UNKNOWN
Conditions: Extrapancreatic Neuroendocrine Tumor
Interventions: DRUG: Tegafur|DRUG: Temozolomide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: BRAF V600 Wild Type|Clinical Stage IV Cutaneous Melanoma AJCC v8|Intracranial Melanoma|Metastatic Malignant Neoplasm in the Brain|Metastatic Melanoma|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Refractory Melanoma
Interventions: DRUG: Atezolizumab|BIOLOGICAL: Bevacizumab|DRUG: Cobimetinib|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis
Status: UNKNOWN
Conditions: Intrauterine Adhesion
Interventions: DRUG: G-CSF|DRUG: Normal saline|DRUG: hormone therapy|OTHER: Cook balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Precise Antiplatelet THerapy Guided by Platelet Aggregation Function in Acute Ischemic STROKE（PATH-STROKE）
Status: RECRUITING
Conditions: Ischemic Stroke|Antiplatelet Drug
Interventions: DRUG: Precision Antiplatelet Therapy Trial Group|DRUG: Traditional Antiplatelet Therapy Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Sirukumab 100 mg|DRUG: Sirukumab 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immunogenicity and Safety of Live Attenuated Poliomyelitis Vaccine (Human Diploid Cell)
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Live attenuated Poliomyelitis vaccine (Human Diploid Cell)|BIOLOGICAL: Live attenuated Poliomyelitis vaccine (Monkey Kidney Cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using Deep Learning Methods to Analyze Automated Breast Ultrasound and Hand-held Ultrasound Images, to Establish a Diagnosis, Therapy Assessment and Prognosis Prediction Model of Breast Cancer.
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: ABUS and HHUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: E-cigarette Switching|BEHAVIORAL: Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study
Status: WITHDRAWN
Conditions: Aortic Valve Stenosis|Valsartan|Angiotensin Receptor Antagonists|Transcatheter Aortic Valve Replacement|Heart Valve Prosthesis Implantation|Hypertrophy, Left Ventricular
Interventions: DRUG: Valsartan|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Brochure in Preparing Patients With Gastric Cancer and Their Caregivers for Recovery After Surgery
Status: WITHDRAWN
Conditions: Anxiety|Gastric Carcinoma|Stress
Interventions: OTHER: Educational Intervention|PROCEDURE: Standard Follow-Up Care|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Music Listening for Wellbeing in Adults With Acquired Visual Impairment
Status: COMPLETED
Conditions: Visual Impairment|Low Vision|Depression|Anxiety|Stress|Emotional Adjustment
Interventions: BEHAVIORAL: Mindful Music Listening|BEHAVIORAL: Music Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Circadian & Homeostatic Synchronization Effect on Waking Mobility in Parkinson's Disease
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: OTHER: Validation of the mobility assessment by IMU wearable sensors|OTHER: Testing in real-life conditions at patients' home in a small group of subjects|OTHER: Testing in real-life conditions at patients' home in a small group of subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Botulinum Toxin Type A Topical Gel for Primary Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fear of Falling in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: GHE + TOBT training|BEHAVIORAL: CBT + TOBT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxford Haemodynamic Adaptation to Reduce Pulsatility Trial
Status: COMPLETED
Conditions: Small Vessel Cerebrovascular Disease
Interventions: DRUG: Sildenafil|DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis
Status: COMPLETED
Conditions: Acute Alcoholic Hepatitis
Interventions: DRUG: Anakinra|DRUG: Pentoxifylline|DRUG: Zinc Sulfate|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supraglottic Airway Devices in Pediatric Difficult Airway Situations
Status: COMPLETED
Conditions: Airway Morbidity|Emergencies
Interventions: DEVICE: Combitube, Easytube, Laryngeal masks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants < 33 Weeks
Status: TERMINATED
Conditions: Prematurity
Interventions: PROCEDURE: Milking group|PROCEDURE: Immediate cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study
Status: UNKNOWN
Conditions: Lung Transplantation|Primary Graft Dysfunction
Interventions: DRUG: Surfactant (calfactant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Neoadjuvant Atezolizumab Treatment in Patients With Advanced Urothelial Bladder Cancer
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: Neoadjuvant atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients
Status: TERMINATED
Conditions: Cigarette Smoking|Methadone Maintenance
Interventions: DRUG: Nicotine Nasal Spray|DRUG: Varenicline|DRUG: Placebo Nasal Spray|DRUG: Placebo Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced Malignant Solid Tumors With Claudin18.2CAR-T
Status: RECRUITING
Conditions: Advanced Pancreatic Carcinoma|Advanced Gastric Carcinoma
Interventions: BIOLOGICAL: Claudin18.2 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Data-driven Approaches to Healthcare Provider Resilience & Burnout During COVID-19
Status: TERMINATED
Conditions: Burnout, Professional|Exhaustion, Caregiver|Covid19
Interventions: BEHAVIORAL: Transcendental Meditation (TM)|BEHAVIORAL: Experience Resolution Methodology (ERM)|BEHAVIORAL: Transcendental Meditation (TM) and Experience Resolution Methodology (ERM)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine Uptake Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccination Refusal|COVID-19
Interventions: OTHER: Short Message Service (SMS) + Website Link Strategy|OTHER: Phone Call with Peer Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of Regenerative Potential of Mature Permanent Teeth With Necrotic Pulps Using Two Revascularization Protocols. (In Vivo Study)
Status: UNKNOWN
Conditions: Apical Periodontitis
Interventions: OTHER: Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Planning Intervention Telehealth Service Model in Emergency Departments
Status: ENROLLING_BY_INVITATION
Conditions: Suicide|Suicidal Ideation
Interventions: BEHAVIORAL: SPI+ Delivered by ED Staff|BEHAVIORAL: SPI+ Delivered by SPCC Clinicians
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Superficial Partial-Thickness Burn Study
Status: TERMINATED
Conditions: Superficial Partial Thickness Burn
Interventions: DEVICE: Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser|DRUG: Silver Sulfadiazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Measuring Differences in Cognition Due to Sedative Effects of Risperidone and Quetiapine in Stable Bipolar I Outpatients
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: risperidone; quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: NBA G-League Sweat Testing Study: Validity of the Gx Sweat Patch in Measuring Sweating Rate and Sweat Chloride Concentration During On-court Training With Basketball Players
Status: COMPLETED
Conditions: Sweat Analysis
Interventions: OTHER: Gx sweat patch|OTHER: Reference sweat patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tranexamic Acid in Reverse Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Shoulder Joint Disease|Complications; Arthroplasty|Intraoperative Complications|Blood Loss, Surgical
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Ultrasound as a Guide Tool During Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Diaphragmatic Ultrasound in Weaning
Interventions: DEVICE: diaphragmatic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Preoperative Respiratory Physical Therapy on Postoperative Respiratory Function After Bariatric Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Respiratory Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Outcomes With tDCS in Post-Stroke Aphasia
Status: RECRUITING
Conditions: Aphasia
Interventions: DEVICE: Active Transcranial Direct Current Stimulation with SLT|DEVICE: Sham Transcranial Direct Current Stimulation with SLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Childhood Outside (ECO) - Randomized Controlled Trial Study
Status: COMPLETED
Conditions: Risk Assessment|Online Intervention|Child Development
Interventions: BEHAVIORAL: RR Digital Tool|BEHAVIORAL: Position Statement on Active Outdoor Play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability and Immunogenicity of an Intranasal Influenza Vaccine Administered to Healthy Adults
Status: COMPLETED
Conditions: Flu, Human
Interventions: BIOLOGICAL: DCB07010|BIOLOGICAL: HA antigens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Electroacupuncture Versus PFMT Plus Solifenacin for Mixed Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: PROCEDURE: acupuncture|DRUG: solifenacin|PROCEDURE: PFMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers
Status: COMPLETED
Conditions: Onset and Duration of a Digital Nerve Block
Interventions: DRUG: Lidocaine Digital Nerve Block|DRUG: Bupivacaine Digital Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Effect of Acupuncture in Neurodegenerative Diseases on Traumatic Brain Injury Patients
Status: NOT_YET_RECRUITING
Conditions: Neurodegenerative Diseases
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cognitive Behavioral Therapy Group Intervention to Increase HIV Testing and PrEP Use Among Latinx Sexual Minority Men
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: CBT Coping Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: F-18 PSMA for Localization of Parathyroid Adenoma
Status: RECRUITING
Conditions: Hyperparathyroidism
Interventions: DIAGNOSTIC_TEST: 99mTc-MIBI planar imaging and SPECT/CT.|DIAGNOSTIC_TEST: F- 18PSMA PET/CT imaging study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Neuropathies|Complex Regional Pain Syndrome Type II|Resistant Peripheral Neuropathic Pain|Chemotherapy Induced Pain Neuropathy
Interventions: DEVICE: TDCS/sham procedure on five consecutive days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Combined With CHOPE Regimen for Peripheral T-cell Lymphoma Patients
Status: UNKNOWN
Conditions: Experimental Tumor
Interventions: DRUG: Chidamide|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Etoposide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influencing Factors of Intracranial Hypertension in Patients With Bilateral Transverse Sinus Stenosis
Status: COMPLETED
Conditions: Vertebral Venous Collaterals|Serum Uric Acid|Intracranial Hypertension|Bilateral Transverse Sinus Stenosis
Interventions: DIAGNOSTIC_TEST: standard lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Percutaneous Lumbar Discectomy Combined With Ozone for Treatment of LDH
Status: UNKNOWN
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: percutaneous lumbar discectomy|PROCEDURE: ozone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Status: COMPLETED
Conditions: Postoperative; Dysfunction Following Cardiac Surgery
Interventions: DRUG: Tetronine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionation With Simultaneous Integrated Boost for Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Surgery|Adjuvant Radiotherapy
Interventions: RADIATION: Hypofractionation with simultaneous integrated boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myoelectric SoftHand Pro to Improve Prosthetic Function for People With Below-elbow Amputations: A Feasibility Study
Status: COMPLETED
Conditions: Upper Limb Amputation Below Elbow (Injury)
Interventions: DEVICE: SoftHand
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females
Status: TERMINATED
Conditions: Cervical Cancer|Genital Wart|CIN1|CIN2|CIN3|Vain I|Vain III|Vin I|Vin II|Vin III|AIS|VAIN - Vaginal Intraepithelial Neoplasia 2
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, and 18) Recombinant Vaccine (Hansenula Polymorpha)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: KD6001 in Combination With Anti-PD-1 Antibody in Patients With Advanced Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: KD6001|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans Cranial Direct Current Stimulation Along With Craniosacral Therapy on Sleep Disturbances in Patients With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Sleep Disturbance|Chronic Low-back Pain
Interventions: DEVICE: Trans cranial Direct Current Stimulation (tDCS)|OTHER: Craniosacral therapy (CST)|OTHER: tDCS+ CST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ozurdex for Treatment of Recalcitrant Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Non-proliferative Diabetic Retinopathy|Proliferative Diabetic Retinopathy
Interventions: DRUG: dexamethasone intravitreal implant|DRUG: intravitreal bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEnile Cancer Radio- and Immunotherapy CLinical Exploration Study
Status: COMPLETED
Conditions: Penile Cancer
Interventions: DRUG: Arm A: Atezolizumab and Radiotherapy|DRUG: Arm B: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearing a Compression Garment for Patients With Hypermobility Type of Ehlers-Danlos Syndrome
Status: UNKNOWN
Conditions: Ehlers-Danlos Syndrome Hypermobility Type
Interventions: DEVICE: short-sleeved vest CICATREX SED®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sub Chronic Evaluation for ATP With an Extravascular Placed ICD Lead (STEP ICD) Study
Status: COMPLETED
Conditions: Ventricular Arrythmia|Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: AtaCor EV-ICD Lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters
Status: UNKNOWN
Conditions: Pain, Postoperative|Wound; Abdomen|Incision
Interventions: DEVICE: Rectus Sheath Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Inhaled Doses of AZD4818 in Healthy Japanese Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD4818|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection
Status: ACTIVE_NOT_RECRUITING
Conditions: Indocyanine Green|Gastric Cancer|Injection Site
Interventions: DRUG: Subserosa injection of indocyanine green|DRUG: submucosal injection of indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apneas in Elderly:Neuroimaging Changes and Neurocognitive Function Before and After Treatment
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DEVICE: CPAP|OTHER: Standard care for OSA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)
Status: RECRUITING
Conditions: Atypical Parkinsonism|MSA - Multiple System Atrophy|PSP|Nurse-Patient Relations|Nurse Physician Relations
Interventions: OTHER: Telemonitoring|OTHER: Standard-of-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intergenerational Reminiscence and Digital Storytelling
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Reminiscence with digital storytelling|BEHAVIORAL: Social wellness with scrapbook or journal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Efficacy of BVS857 in Patients With Spinal and Bulbar Muscular Atrophy
Status: COMPLETED
Conditions: Spinal and Bulbar Muscular Atrophy
Interventions: DRUG: BVS857|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol Supplement in Treating Patients With Localized Prostate Cancer Undergoing Observation
Status: COMPLETED
Conditions: Prostate Adenocarcinoma
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|OTHER: Laboratory Biomarker Analysis|OTHER: Patient Observation|DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia
Status: UNKNOWN
Conditions: Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance Schizophrenia
Interventions: DEVICE: deep transcranial magnetic stimulation with H7 coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TEXT4HF: Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: BEHAVIORAL: TEXT4HF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: LBH589 (i.v. panobinostat)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenexx™ SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to TKA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Regenexx SD|BEHAVIORAL: Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
Status: WITHDRAWN
Conditions: Peptic Ulcer Bleeding
Interventions: DEVICE: heat probe or hemoclip|DEVICE: heat probe or hemoclip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition Care in Patients Living With Chronic Pain
Status: NOT_YET_RECRUITING
Conditions: Nutrition Poor|Overweight and Obesity|Mobile Phone Use|Pain, Chronic
Interventions: OTHER: Nutrition care|BEHAVIORAL: Dialogue and education (part of Interdisciplinary Pain Rehabilitation Program)|BEHAVIORAL: activity training (part of Interdisciplinary Pain Rehabilitation Program)|BEHAVIORAL: meetings (part of Interdisciplinary Pain Rehabilitation Program)|BEHAVIORAL: Cognitive behavioral therapy (part of Interdisciplinary Pain Rehabilitation Program)|BEHAVIORAL: Relaxation techniques (part of Interdisciplinary Pain Rehabilitation Program)|BEHAVIORAL: Physical exercise (part of Interdisciplinary Pain Rehabilitation Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine Effectiveness Against Recurrent Infection Among Lung Cancer Patients and Biomarker Research
Status: RECRUITING
Conditions: COVID-19 Recurrent|Lung Cancer|Vaccination|Antibody|Chemotherapy|Immune Checkpoint Inhibitor
Interventions: BIOLOGICAL: Any Chinese government-recommended COVID-19 booster vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine vs. Azithromycin for Hospitalized Patients With Suspected or Confirmed COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal Laser Single Intravitreal Ranibizumab Retinal Artery Macroaneurysm.
Status: COMPLETED
Conditions: Retinal Artery Macroaneurysm
Interventions: PROCEDURE: Dual focal laser and intravitreal Ranibizumab injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Renal and Cardiac Risk Factors of AKI After Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury|Acute Renal Injury|Liver Transplant; Complications
Interventions: DIAGNOSTIC_TEST: renal resistive index and myocardial performance index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogenic Plasma Aliquots in the Treatment of Ligneous Conjunctivitis
Status: ENROLLING_BY_INVITATION
Conditions: Ligneous Conjunctivitis, Left Eye
Interventions: BIOLOGICAL: Allogenic plasma aliquots, a source of plasminogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Treatment Versus no Therapy in Kidney Transplant Recipients With Asymptomatic Bacteriuria
Status: UNKNOWN
Conditions: Asymptomatic Bacteriuria|Pyelonephritis
Interventions: DRUG: Antibiotic treatment|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SLAP Repair vs. Biceps Tenodesis in Patients Under 30: A Randomized Clinical Trial
Status: COMPLETED
Conditions: SLAP Tear
Interventions: PROCEDURE: Self-Locking Tenotomy|PROCEDURE: Biceps Tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF to Assess Real-life Usage Effectiveness, Safety and Patient Satisfaction of a Range of Hypertonic Seawater-based Decongestant Nasal Sprays
Status: RECRUITING
Conditions: Allergic Rhinitis|URTI
Interventions: DEVICE: ProRhinel Naturel spray nasal/ Allergic rhinitis|DEVICE: ProRhinel EXTRA Eucalyptus spray nasal|DEVICE: RESPIMER Enfant|DEVICE: Phytosun Aroms spray nasal MAX|DEVICE: PHYSIOMER RHUME TRIPLE ACTION|DEVICE: Phytosun Aroms spray nasal decongestionnant|DEVICE: ProRhinel Naturel spray nasal/ URTI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Retrospective Registry of Anterior Communicating Artery Aneurysms With Endovascular Therapy
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Anterior Communicating Artery Aneurysm|Cerebral Aneurysm|Aneurysm, Ruptured
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Buspirone, Stress, and Attentional Bias to Marijuana Cues
Status: COMPLETED
Conditions: Cannabis Use Disorder
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beating Heart Mitral Valve Repair With the HARPOON™ System
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: HARPOON™ Beating Heart Mitral Valve Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAFLD Primary Care
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Cardiovascular Diseases|Type2 Diabetes|Metabolic Syndrome|Overweight and Obesity
Interventions: DIAGNOSTIC_TEST: FibroScan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of DWJ1351 in Healthy Male Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: DWJ1351|DRUG: Co-administration of Sevikar (Olmesartan/Amlodipine) and Crestor (Rosuvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia
Status: COMPLETED
Conditions: Chronic Sinusitis With Nasal Polyps and Eosinophilia
Interventions: DRUG: dexpramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACTIVATE in Public Housing
Status: NOT_YET_RECRUITING
Conditions: Pneumonia|Influenza|Varicella Zoster|Meningitis|COVID-19|Vaccine Hesitancy
Interventions: BEHAVIORAL: Increasing Willingness and Uptake of Influenza, Pneumonia, Meningitis, HZV, and COVID-19 Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Hysterectomy With Prior Uterine Artery Ligation
Status: COMPLETED
Conditions: Uterine Artery Injury|Hysterectomy
Interventions: PROCEDURE: conventional Total laparoscopic hysterectomy|PROCEDURE: Total laparoscopic hysterectomy with prior uterine artery ligation at its origin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Arbaclofen in 16p11.2 Deletion
Status: ACTIVE_NOT_RECRUITING
Conditions: 16P11.2 Deletion Syndrome
Interventions: DRUG: Arbaclofen|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactions Between Neurostimulation and Physical Exercise
Status: WITHDRAWN
Conditions: Spinal Cord Injuries|Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Cervical plus transcranial stimulation|DEVICE: Cervical stimulation plus hand/wrist exercise|DEVICE: Electromyographic (EMG)-triggered (closed-loop) stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Analysis of Adverse Events and Satisfaction Outcomes of Women Who Underwent Primary and Secondary Breast Augmentation Using Silimed® Breast Implants
Status: RECRUITING
Conditions: Breast Implant; Complications|Quality of Life|Satisfaction
Interventions: DEVICE: Silimed® Textured Silicone Gel-Filled Breast Implant|DEVICE: Silimed® Polyurethane Foam Covered Silicone Gel-Filled Breast Implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Different Exercise Modalities in the Treatment of NAFLD and Their Impact on Myokines
Status: RECRUITING
Conditions: NAFLD|Nonalcoholic Fatty Liver Disease|Fatty Liver, Nonalcoholic|Fatty Liver
Interventions: OTHER: Exercise|BEHAVIORAL: Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Systemic Corticosteroids and the Recovery of Gustatory Functions in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19|Olfactory Dysfunction
Interventions: DRUG: Administration of Systemic Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coload Optimization Guided by Inferior Vena Cava Collapsibility Index
Status: COMPLETED
Conditions: Adverse Effect
Interventions: DRUG: 4 ml/kg group|DRUG: 8 ml/kg group|DRUG: 12 ml/kg group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen for Fetal Tachycardia: a Randomized Pilot Trial
Status: TERMINATED
Conditions: Fever|Heart Rate, Fetal (FHR)
Interventions: DRUG: Acetaminophen 975 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Different Plane Blocks on Post-thoracotomy Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Thoracotomy|Erector Spinae Plane Block|Serratus Anterior Plane Block
Interventions: PROCEDURE: Continuous Erector Spina Plane Block vs Continuous Serratus Anterior Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in Participants With Moderate to Severe Plaque-type Psoriasis and an Inadequate Response to Ustekinumab
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ustekinumab|DRUG: Guselkumab|DRUG: Placebo for ustekinumab|DRUG: Placebo for guselkumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultraslow SWL Versus Slow SWL for Renal Stones With High Attenuation Value
Status: UNKNOWN
Conditions: Renal Stones
Interventions: PROCEDURE: SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Sitagliptin When Given Together to Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP1941
Interventions: DRUG: ASP1941|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Vitamin D, Blood Pressure, Lipids, Infection and Depression
Status: COMPLETED
Conditions: Hypovitaminosis D
Interventions: DRUG: Cholecalciferol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Amantadine Hydrogen Chloride (HCl) ER Tablets in Parkinson's Disease Subjects With LID
Status: TERMINATED
Conditions: Parkinson's Disease|Levodopa Induced Dyskinesia (LID)
Interventions: DRUG: amantadine HCl ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)
Status: COMPLETED
Conditions: Invasive Candidiasis
Interventions: DRUG: caspofungin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Safety and Immunogenicity of Various Schedules of Dengue Vaccine in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Takeda's Tetravalent Dengue Vaccine Candidate (TDV)|BIOLOGICAL: TDV New Formulation|DRUG: Placebo|DRUG: New Formulation Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: BIOLOGICAL: NGM282|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of the Clinical Efficacy of Short Implants With Standard-Length Implants - a Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Dental Implant
Interventions: PROCEDURE: Dental Implant Surgery - short implant group (less than or equal to 6mm)|PROCEDURE: Dental Implant Surgery - Conventional implant group (greater than or equal to 10mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.
Status: RECRUITING
Conditions: Retinal Disease|Macular Degeneration|Age-Related Macular Degeneration|Geographic Atrophy|Eye Diseases
Interventions: DRUG: Eyecyte-RPE™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudication
Status: RECRUITING
Conditions: Peripheral Artery Disease|Intermittent Claudication
Interventions: BEHAVIORAL: Walking exercise behaviour change intervention + TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Pharmacokinetic Study of ND0611 on the Top of Different Oral Dosage Forms of Levodopa/Carbidopa in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Saline|DRUG: Carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Datopotamab Deruxtecan|DRUG: Pembrolizumab|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Blood Loss in Laparoscopic vs Open Pancreaticoduodenectomy in Patients With Periampullary Carcinoma
Status: UNKNOWN
Conditions: Periampullary Carcinoma
Interventions: PROCEDURE: pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of High Mechanical Index Ultrasound Impulses on Left Ventricular Stroke Volume With Intravenous Microbubbles
Status: WITHDRAWN
Conditions: Cardiac Disease
Interventions: DIAGNOSTIC_TEST: high MI impulses|DIAGNOSTIC_TEST: low MI impulses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study Evaluating the Safety and Effectiveness of a New Pleural Catheter for the Medical Management of Symptomatic, Recurrent, Malignant Pleural Effusions
Status: COMPLETED
Conditions: Malignant Pleural Effusions
Interventions: DEVICE: New Indwelling Pleural Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT