pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of High Intensity Laser in Treatment of Myofascial Trigger Points in Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain|Knee Osteoarthritis
Interventions: RADIATION: High intensity laser treatment|DEVICE: sham HILT.|OTHER: knee osteoarthritis conventional exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nimotuzumab Combinated With Gemcitabine in K-RAS Wild-type Locally Advanced and Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: nimotuzumab|DRUG: Gemcitabine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: DRUG: RP-G28|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Morphine Sulfate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib (BMS-354825) in Subjects With Myeloid Blast Phase Chronic Myeloid Leukemia Resistant to or Intolerant of Imatinib Mesylate
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia|Blast Crisis
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Extracorporeal Shock Wave Therapy in Patients With Coccydynia: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Coccydynia
Interventions: DEVICE: Extracorporeal shock wave therapy (ESWT)|DEVICE: SWD combined IFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention for Sexual and Biomedical HIV Prevention in Vulnerable U.S. Young Adults
Status: RECRUITING
Conditions: Economic Hardship|Condomless Sex|Utilization, Health Care
Interventions: BEHAVIORAL: Job announcements plus educational sessions, mentoring, a micro-grant, and behavioral economic text messages|BEHAVIORAL: Job announcements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Patient Preference Between ODM-201 and Enzalutamide in Men With Metastatic Castrate-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castrate-resistant Prostate (CRPC) Cancer
Interventions: DRUG: ODM-201|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Cohort Study on Screening and Follow-up of High-risk Population of PDAC Based on EUS
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Pancreatic Ductal
Interventions: DEVICE: Endoscopic ultrasound|PROCEDURE: EUS-Fine needle aspiration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Versus Intravenous Sedation for Ocular Procedures
Status: COMPLETED
Conditions: Surgery|Sedation
Interventions: DRUG: Triazolam|DRUG: Midazolam|DRUG: Microcrystalline Cellulose|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Supplementation With L-ornithine But Not L-arginine Increases Density of CD68+ and CD163+ Macrophages in Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|DRUG: Oral L-arginine aspartate administration|DRUG: Oral L-ornithine aspartate administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Efficacy of Malaria Vaccine PfCS 102
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: PfCS102|BIOLOGICAL: Montanide ISA 720
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of TENS Therapy for Premature Ejaculation
Status: RECRUITING
Conditions: Premature Ejaculation|Sex Disorder|TEN
Interventions: DEVICE: Tens therapy|DRUG: Dapoxetine placebo|DRUG: Standard treatment (dapoxetine 30 mg as needed)|DEVICE: Placebo therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of NLS-2 (Mazindol Extended Release) in Subjects With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy With Cataplexy|Narcolepsy|Narcolepsy Without Cataplexy
Interventions: DRUG: Mazindol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breathing Events Detected by the SleepStyle 200 Auto Continuous Positive Airway Pressure (CPAP) Device to Attended Polysomnography
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: SleepStyle 200 Auto Series CPAP Humidifier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain|Low Back Pain, Recurrent
Interventions: DRUG: JNJ-42160443 3 mg|DRUG: JNJ-42160443 1 mg|DRUG: JNJ-42160443 6 mg/3mg|DRUG: JNJ-42160443 10 mg|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut Microbiota
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sevelamer 1600 mg TID for 7 days|DRUG: Placebo 1600 mg TID for 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-blind, and Placebo-controlled Study on the Treatments of Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Pinaverium|DEVICE: Atractylodes|DEVICE: Paeonia Lactiflora|DEVICE: Tangerine Peel|DRUG: Ledebouriella Root|DRUG: Radix codonopsitis|DRUG: Radix curcumae|DRUG: Fingered citron|DRUG: Tuckahoe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Bioceramic Putty MTA Versus MTA in Pulpotomy of Immature Permanent Molars
Status: NOT_YET_RECRUITING
Conditions: Pulpotomy|Deep Caries
Interventions: DRUG: premixed Bio-ceramic MTA|DRUG: Conventional MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesiophobia and Physical Fitness, and Related Factors in Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplant Disorder
Interventions: OTHER: Assessment of: 1. Functional Capacity 2. Physical Fitness 3. Physical Activity Level 4. Balance 5. Kinesiophobia 6. Psychological Status 7. Fatigue Severity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: rTMS for Post-stroke Fatigue
Status: RECRUITING
Conditions: Stroke|Stroke, Chronic|Fatigue
Interventions: DEVICE: High frequency repetitive transcranial magnetic stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Focal Epicardial Cryoablation During Mei Mini Maze Procedure in Treatment of Lone Atrial Fibrillation
Status: UNKNOWN
Conditions: Lone Atrial Fibrillation
Interventions: PROCEDURE: Epicardial focal cryoablation|PROCEDURE: Mei Mini Maze procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Plus Ribavirin in Treating Older Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: pegylated interferon alpha and plus ribavirin|DRUG: pegylated interferon alpha and plus ribavirin|DRUG: pegylated interferon alpha and plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Proellex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Whipple Procedure: Standard of Care vs. Thunderbeat
Status: TERMINATED
Conditions: Pancreatic Neoplasms|Bile Duct Carcinoma
Interventions: DEVICE: Thunderbeat|DEVICE: Standard of care scissors, ligatures, clips, and sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of GIMate Handheld Hydrogen Breath Monitor for Diagnosis of Lactose Malabsorption
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: DIAGNOSTIC_TEST: GIMate|DIAGNOSTIC_TEST: H2 Check
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Altering Bicarbonate Delivery During Hemodialysis to Affect Filtration of Indoxyl Sulfate
Status: WITHDRAWN
Conditions: Renal Dialysis|Hemodialysis
Interventions: DRUG: Low bicarbonate dialysate First|DRUG: Normal bicarbonate dialysate First|DRUG: Normal bicarbonate dialysate|DRUG: Low bicarbonate dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone-induced Hiccup in Chemotherapy Patients Treated by Methylprednisolone Rotation
Status: COMPLETED
Conditions: Dexamethasone-induced Hiccup in Chemotherapy
Interventions: DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Young Parents Program, Project Connect
Status: COMPLETED
Conditions: Adolescents|18 and Under When Child Was Born for Mothers|25 and Under When Child Was Born for Fathers
Interventions: BEHAVIORAL: Parenting/Life Skills Intervention|OTHER: Teen-tot medical home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness of Perioperative CPAP to Reduce Obstructive Sleep Apnea Related Adverse Events
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: auto-titrated CPAP|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Bone-marrow Derived Mesenchymal Stromal Cells Associated With Endobronchial Valves in Emphysema
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: PROCEDURE: Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Childhood|Pediatric Obesity|Childhood Obesity|Adolescent Obesity|Overweight|Overweight and Obesity|Overweight or Obesity|Overweight Adolescents|Weight Gain|Overnutrition|Body Weight|Body Weight Changes|Nutrition Disorders
Interventions: BEHAVIORAL: eSOC program|BEHAVIORAL: FBT program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Pump-RT Advisor (IPRA©): a Decision Support Software for Diabetic Patients Treated by Insulin Pump and Using Continuous Glucose Monitoring. Experimental Study. Evaluation by an Expert Patient Panel.
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: A decision support software|OTHER: Insulin Pump|OTHER: Continuous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Tolerability of BMS-986183 in Patients With Liver Cancer
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: BMS-986183|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection of Clinical and Instrumental Data in Adult Subjects Suffering From Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Clinical evaluations|OTHER: Non-invasive instrumental measurements|OTHER: Subject's evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Chinese Medicine JCM-16021 for Diarrhea-predominant Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: JCM-16021|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Non-Surgical Periodontal Treatment on Gingival Crevicular Fluid and Serum Biomarker Levels
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Gingivitis|Healthy
Interventions: OTHER: Clinically Helathy|OTHER: Gingivitis|OTHER: Periodontitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Macular Detachment Associated With Intrachoroidal Cavitation
Status: COMPLETED
Conditions: Macular Detachment|Macular Retinoschisis|Intrachoroidal Cavitation
Interventions: OTHER: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2171 in Treating Patients With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: cediranib maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Find The Best Doses Of SU011248 (Sunitinib) And Capecitabine When These Drugs Are Administered Together
Status: COMPLETED
Conditions: Solid Tumors|Breast Cancer|Neoplasms
Interventions: DRUG: SU011248; Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of "3-Hole" Subxiphorid Approach in the Treatment of Anterior Mediastinal Tumor
Status: RECRUITING
Conditions: Thymectomy|Myasthenia Gravis
Interventions: PROCEDURE: "3-Hole" subxiphorid and subcostal approach|PROCEDURE: Trans sternal approach|PROCEDURE: VATS approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: methotrexate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study on the Significance of Auricular Clip in Prevention and Treatment of Valvular Heart Disease Atrial Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Thrombus; Embolism|Warfarin|Atrial Appendage|Surgery
Interventions: DEVICE: atrial appendage clip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Icotinib as the Adjunctive Treatment After Surgery in Stage I-IIIB Lung Adenocarcinoma Patients With EGFR Gene Mutation
Status: UNKNOWN
Conditions: Neoplasms, Therapy-Associated
Interventions: DRUG: Icotinib|DRUG: chemotherapy (Carboplatin and Docetaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial Evaluating BP1.3656 Versus Placebo For Alcohol Use Disorder Treatment
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: BP1.3656 low dose|DRUG: BP1.3656 intermediate dose|DRUG: Placebo|DRUG: BP1.3656 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety Of Tolterodine Extended Release Capsule Compared With Tolterodine Immediate Release Tablet
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: tolterodine extended release capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Validating the "Foods for Health" Portfolio of Functional Food Products
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: OTHER: Portfolio of functional foods|OTHER: Control foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Combined Fractional Carbon Dioxide Laser and Topical Tazarotene in the Treatment of Psoriatic Nail Disease
Status: UNKNOWN
Conditions: Nail Psoriasis
Interventions: DEVICE: fractional carbon dioxide laser|DRUG: Tazarotene Cream 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Review of a Decision Aid Prior to the Appointment on Decisional Conflict Compared to Usual Care in the Treatment of Trapeziometacarpal (TMC) Arthritis
Status: COMPLETED
Conditions: Trapeziometacarpal Arthritis
Interventions: BEHAVIORAL: Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Pono Choices: A Culturally Responsive Teen Pregnancy and STI Prevention Program
Status: COMPLETED
Conditions: Teen Pregnancy|Sexually Transmitted Infections
Interventions: BEHAVIORAL: Pono Choices|BEHAVIORAL: Business as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Two Different Dietary Interventions for Girls With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Obesity|Androgen; Hypersecretion|Diet, Healthy
Interventions: BEHAVIORAL: intervention diet|BEHAVIORAL: control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of AGN-214868 in Patients With Postherpetic Neuralgia
Status: TERMINATED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: AGN-214868|DRUG: AGN-214868 Placebo (Vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer American Joint Committee on Cancer (AJCC) v8|Metastatic Breast Carcinoma|Metastatic Malignant Neoplasm in the Brain|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Abemaciclib|DRUG: Palbociclib|OTHER: Quality-of-Life Assessment|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: 700 µg Dexamethasone|DRUG: 350 µg Dexamethasone|OTHER: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness
Status: COMPLETED
Conditions: Intensive Care Unit|Muscle Weakness
Interventions: DEVICE: Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)
Status: RECRUITING
Conditions: Transgenderism
Interventions: DIAGNOSTIC_TEST: Static and dynamic perineo-pelvic MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intermittent Vacuum Therapy Combined With Aerobic Exercise in Individuals With Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Intermittent vacuum therapy (Weyergans High Care® Medial, Germany)|BEHAVIORAL: Cycling exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem
Status: COMPLETED
Conditions: Hypertension|Craniotomy
Interventions: DRUG: Diltiazem|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autosomal Dominant Retinitis Pigmentosa: Prevalence of Known Genes Identification of New Loci / Genes
Status: COMPLETED
Conditions: Autosomal Dominant Retinitis Pigmentosa
Interventions: GENETIC: genetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: INCB059872
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies
Status: COMPLETED
Conditions: Oncology|MET Gene Amplification|NSCLC|MET Gene Mutation|Non Small Cell Lung Cancer
Interventions: DRUG: Sym015
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by Chemiotherapy
Status: TERMINATED
Conditions: DLBCL
Interventions: DRUG: Entospletinib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal rhGDF-5 for the Treatment of Early Stage Lumbar Disc Degeneration
Status: COMPLETED
Conditions: Early Lumbar Disc Degeneration
Interventions: DRUG: Intradiscal rhGDF-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: ATHENAS - Retrospective Study of Compliance in Chronic Hepatitis C With Pegylated Interferon Alfa-2b/Ribavirin in Brazil (P05632)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of a Facemask Device to Treat Hypotension
Status: COMPLETED
Conditions: Hypotension
Interventions: DEVICE: Impedance Threshold Device|DEVICE: sham ITD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phacoemulsification vs SLT as Initial Treatment for Pseudoexfoliation Glaucoma
Status: RECRUITING
Conditions: Pseudoexfoliation Glaucoma
Interventions: PROCEDURE: Phacoemulsification|DEVICE: Selective Laser Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Prostatic Hyperplasia, Benign|Enlarged Prostate With Lower Urinary Tract Symptoms
Interventions: DEVICE: Embosphere microparticles for prostate artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Modeling Resin on Anterior Direct Composite Veneer
Status: NOT_YET_RECRUITING
Conditions: Dental Wear|Dental Decay
Interventions: DEVICE: Modeling Resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Anesthetic Efficacy of Dexmedetomidine and Epinephrine With Lidocaine in Irreversible Pulpitis
Status: UNKNOWN
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Inferior alveolar nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Quality of National Quality Indicators in Long-term Care Facilities: a Validation and Evaluation Study
Status: RECRUITING
Conditions: Reliability of National Quality Indicator Data
Interventions: BEHAVIORAL: Program to improve data quality of national quality indicators
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss
Status: COMPLETED
Conditions: Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: Low carbohydrate ketogenic diet|DRUG: Orlistat|BEHAVIORAL: Low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thai Prophylactic HIV Vaccine Phase I Study
Status: TERMINATED
Conditions: HIV
Interventions: BIOLOGICAL: pHIS-HIV-AE (DNA vaccine) prime and rFPV-HIV-AE (recombinant fowlpox virus boost) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
Status: COMPLETED
Conditions: Choledocholithiasis
Interventions: DIAGNOSTIC_TEST: Endosonography|DIAGNOSTIC_TEST: Magnetic Resonance Cholangiopancreatography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ATI-450 vs Placebo in Patients With Moderate to Severe Hidradenitis Suppurativa (HS)
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: ATI-450|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Digital Intervention Protocol to Enhance Recovery After Head and Neck Surgery
Status: COMPLETED
Conditions: Head and Neck Carcinoma
Interventions: DEVICE: Fitbit|OTHER: Questionnaire Administration|DEVICE: Virtual Reality Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preliminary Exploration on the Operational Standards of Insulin Pump Installation in Diabetes Clinic in China
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus|Gestational Diabetes Mellitus|Pancreatogenic Diabetes Mellitus|Pregestational Diabetes Mellitus|Diabetes Patients in Perioperative Period
Interventions: DEVICE: Insulin pump (Microtech, Equil®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Relaxing Breathing Combined With Biofeedback on the Performance and Stress of Residents During HFS
Status: COMPLETED
Conditions: Stress, Psychological|Stress, Physiological|Performance Anxiety|Critical Incident
Interventions: OTHER: breathing exercise/HRV-biofeedback|OTHER: Relaxing Breathing|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study of Effects of Duavee® on Imaging and Blood Biomarkers In Women With Menopausal Symptoms
Status: TERMINATED
Conditions: Focus of Study is Healthy Women at Risk for Breast Cancer
Interventions: DRUG: DUAVEE 0.45Mg-20Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of PRC-063 in Adult ADHD Patients
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: Placebo|DRUG: PRC-063 25 mg|DRUG: PRC-063 45 mg|DRUG: PRC-063 70 mg|DRUG: PRC-063 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
Status: RECRUITING
Conditions: Recurrent Prostate Cancer After Surgery
Interventions: RADIATION: Daily-adaptive Stereotactic Body Radiation Therapy|RADIATION: Daily-adaptive Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: RO7428731
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Assess the Safety, Tolerability and PK of Risperidone Extended Release Capsules
Status: COMPLETED
Conditions: Schizophrenia Schizoaffective
Interventions: DRUG: LYN-005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Diluted Povidone Iodine Irrigation in Spine Surgery
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DRUG: Povidone-Iodine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Placebo|DRUG: TAK-079
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Food Effects Study of PBTZ169
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: PBTZ169 640 mg OD|DRUG: PBTZ169 640 mg BiD|DRUG: PBTZ169 960 mg SD|DRUG: PBTZ169 1280 mg SD|DRUG: PBTZ169 1280 mg MD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cidofovir in Renal Transplant Recipients With BKVN
Status: TERMINATED
Conditions: BK Virus (Nephropathy)
Interventions: DRUG: Cidofovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Dose Finding Study of Givinostat to Treat Polyarticular Course Juvenile Idiopathic Arthritis
Status: TERMINATED
Conditions: Polyarticular Course Juvenile Idiopathic Arthritis
Interventions: DRUG: Givinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR3680 in Combination With SHR3162 in the Treatment of mCRPC
Status: UNKNOWN
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: SHR3680|DRUG: SHR3162|DRUG: SHR3680(Placebo)|DRUG: SHR3162(Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GnRH Agonist as Luteal Support in FET Cycles
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Natural cycle: Triptorelin acetate 0.1 mg|DRUG: Hormone replacement cycle and triptorelin acetate 0.1 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Precutting Versus Conventional Over-the-Wire Sphinchterotomy For Managment Of Large Common Bile Duct Stones
Status: RECRUITING
Conditions: Calcular Obstructive Jaundice
Interventions: PROCEDURE: sphincterotomy|PROCEDURE: precutting of the papilla by knife needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Postoperative Cognitive Dysfunction|Neurological Impairment
Interventions: DEVICE: INVOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of PLX2853 in Advanced Malignancies.
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Uveal Melanoma|Ovarian Clear Cell Carcinoma|Non-Hodgkin Lymphoma|Advanced Malignancies|Solid Tumor|Diffuse Large B Cell Lymphoma|Follicular Lymphoma
Interventions: DRUG: PLX2853
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Prognosis for Non-functional Neuroendocrine Tumors of the Pancreatic Body and Tail ≤ 3cm
Status: RECRUITING
Conditions: Non Functioning Pancreatic Endocrine Tumor
Interventions: OTHER: Histopathological review, long-term prognosis and quality of life follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Visual Plasticity During Adversity and Prosperity in Infants With Congenital Cataracts
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: bilateral cataract removal surgery for dense cataract|PROCEDURE: bilateral cataract removal surgery for non-dense nuclear cataract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalised Health Recommendations to the General Population Through an Integrated AI Guided
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Cancer Prevention|Helicobacter Pylori Infection|Artificial Intelligence
Interventions: BEHAVIORAL: Health reccommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Relation Between Position of the Uterus (Anteversion or Retroversion Flexion) and Degree of Cesarean Scar Niche
Status: COMPLETED
Conditions: Anteversion of Uterus|Retroflex Uterus|CSD
Interventions: DIAGNOSTIC_TEST: Caesarean scar defect evlauation by ultraosund
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase Ⅰ Clinical Trial of a Candidate COVID-19 Vaccine
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant COVID-19 Vaccine (chimpanzee adenovirus vector) for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity Trial of Recombinant Influenza Vaccine Among HCP in Israel
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flublok™ Quadrivalent by Sanofi, Inc.|BIOLOGICAL: VaxigripTetra™ by Sanofi, Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6
Status: RECRUITING
Conditions: Cutaneous Melanoma|Mucosal Melanoma
Interventions: DRUG: Nemvaleukin Alfa Subcutaneous|DRUG: Nemvaleukin Alfa Intravenous|DRUG: Nemvaleukin Alfa Intravenous Less Frequent Dosing|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: JTZ-951|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Pharmacokinetics and Safety of CT-P17 and Humira in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CT-P17|BIOLOGICAL: US-licensed Humira|BIOLOGICAL: EU-approved Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Sub-gingival Air-polishing With Erythritol in the Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis, Adult|Periodontitis, Aggressive
Interventions: DEVICE: Perioflow and Erythritol powder and ultrasonic debridement|DEVICE: Airflow and Erythritol powder and ultrasonic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pulmonary Ventilation Function Between Patients With Primary and Recurrent Incisional Hernia: a Cross-sectional Study
Status: COMPLETED
Conditions: Incisional Hernia|Recurrent Hernia|COPD|Pulmonary Ventilation Function
Interventions: BEHAVIORAL: the incisional hernia recurrent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Efficacy of Cryotherapy Combined With Intralesional Hepatitis B Virus Vaccine Versus Either Therapy in the Treatment of Multiple Cutaneous Warts :a Comparative Study
Status: NOT_YET_RECRUITING
Conditions: Cutaneous Warts
Interventions: DRUG: Hepatitis B Virus Vaccine(HBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TraMel-WT: A Trial of Trametinib in Patients With Advanced Pretreated BRAFV600 Wild-type Melanoma
Status: COMPLETED
Conditions: Stage IV Melanoma|Stage III Melanoma
Interventions: DRUG: Trametinib|DRUG: Dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
Status: RECRUITING
Conditions: Deviated Nasal Septum
Interventions: DRUG: Ropivacaine|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Effect of Food on the Bioavailability of Glipizide
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: 10 mg Glipizide Tablet (Geneva Pharmaceutical, Inc.), Administered Immediately After a Standard Breakfast.|DRUG: 10 mg Glucotrol Tablet (Roerig), Administered Immediately After a Standard Breakfast.|DRUG: 10 mg Glipizide Tablet (Geneva Pharmaceutical, Inc.), Administered After an Overnight Fast.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)
Status: TERMINATED
Conditions: Polycythemia Vera
Interventions: DRUG: Hydroxyurea|PROCEDURE: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Budesonide Intrapolyp Injection in CRSwNP
Status: UNKNOWN
Conditions: CRS|Polyp, Nasal
Interventions: DRUG: Budesonide intrapolyp injection|DRUG: Budesonide nasal wash|DRUG: Prednisolone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preparation Design on the Functional and Esthetic Outcome of CAD/CAM Lithium Disilicate Laminate Veneers
Status: UNKNOWN
Conditions: Dental Disorders Hard Tissues of Teeth|Tooth Discoloration
Interventions: PROCEDURE: Laminate veneers preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
Status: UNKNOWN
Conditions: Cerebral Palsy|Perceptual Disorders|Hemiparesis
Interventions: BEHAVIORAL: Motor, cognitive and neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor (Phase 1)|Pancreas Adenocarcinoma|Non-small Cell Lung Cancer|Malignant Melanoma (Cutaneous)
Interventions: DRUG: IMM-6-415
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal Radiation Therapy for the Treatment of Low or Intermediate-Risk Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8
Interventions: RADIATION: High-Dose Rate Brachytherapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Tranilast in Patients With Active Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Active Rheumatoid Arthritis
Interventions: DRUG: Tranilast|DRUG: Tranilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety of AC-170 Ophthalmic Solution
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AC-170 0.24%|DRUG: AC-170 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT