pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men
Status: COMPLETED
Conditions: Gonorrhea|Chlamydia|Syphilis
Interventions: DRUG: Doxycycline Hyclate Delayed-Release 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nivolumab-ipilimumab and Chemoradiation for Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms
Interventions: DRUG: Nivolumab 40 mg in 4 ml Injection|DRUG: Ipilimumab 200 MG in 40 ML Injection|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EnteroCT With Enteroclysis Versus Enterography-MRI for the Diagnosis of Tumors of the Small Intestine: a Pilot Study
Status: UNKNOWN
Conditions: Suspicion of Tumor of the Small Intestine
Interventions: RADIATION: Enterography-MRI without enteroclysis|RADIATION: enteroCT with enteroclysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy And Safety Of Azithromycin SR Compared With Minocycline In Acne
Status: TERMINATED
Conditions: Acne Vulgaris
Interventions: DRUG: Azithromycin microspheres|DRUG: minocycline-placebo capsules|DRUG: Azithromycin microspheres-placebo|DRUG: Minocycline capsules,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Efficacy And Safety Of Bismuth Tripotassium Dicitrate (De-Nol) In Combination With Pantoprazole And Pantoprazole Monotherapy In Treatment Of Subjects With Nonsteroidal Anti-Inflammatory Drugs (NSAID)-Induced Gastropathy
Status: TERMINATED
Conditions: NSAID-induced Gastropathy
Interventions: DRUG: bismuth tripotassium dicitrate|DRUG: pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orthopaedic Manipulation in Treatment of Adolescent Idiopathic Scoliosis
Status: NOT_YET_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Manipulation Techniques|OTHER: Physiotherapy Scoliosis-Specific Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Elastic Bandage With Tension on the Inflammatory Response of Hypertrophic Scars
Status: COMPLETED
Conditions: Burns|Hypertrophic Scar
Interventions: OTHER: kinesio tape with tension|OTHER: kinesio tape without tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia Grade 1|Human Papilloma Virus Infection
Interventions: DRUG: placebo|DIETARY_SUPPLEMENT: defined green tea catechin extract|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PeriOperative ISchemic Evaluation-3 Trial
Status: COMPLETED
Conditions: Perioperative Bleeding|Venous Thrombosis|Arterial Thrombosis
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo (Saline)|OTHER: Perioperative hypotension-avoidance strategy|OTHER: Perioperative hypertension-avoidance strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Responses to E-cigarette Message Source and Presentation
Status: NOT_YET_RECRUITING
Conditions: Vaping
Interventions: OTHER: Expert|OTHER: Peer|OTHER: 1 Sided|OTHER: 2 Sided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study for the Identification of Biomarker Signatures for Diagnosis of Pulmonary Hypertension (PH) in Participants at Low or Intermediate Probability of PH Undergoing Cardiac Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: OTHER: Blood Sample|DIAGNOSTIC_TEST: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of an Infant Formula Containing Hydrolysed Proteins on Growth and Tolerance in Healthy Term Infants
Status: COMPLETED
Conditions: Growth
Interventions: OTHER: infant formula based on hydrolyzed protein|OTHER: infant formula based on intact protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fluorine F 18 FEQA in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer and in Healthy Participants
Status: TERMINATED
Conditions: Lung Cancer
Interventions: PROCEDURE: fluorine F 18 FEQA + positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Immunoglobulins for Prevention of BKV Infection in Kidney Transplant Recipients According to BKV Genotype-specific Neutralizing Antibody Titers at the Day of Transplantation.
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Intravenous immunoglobulins (IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Performance Evaluation of mGlobal L+AS 20 mg/ml Hyaluronic Acid, for the Correction of Light to Moderate Wrinkles and Folds
Status: COMPLETED
Conditions: Skin Aging|Skin Wrinkling
Interventions: DEVICE: mGlobal L+AS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion
Status: RECRUITING
Conditions: Pleural Effusion, Malignant|Lung Cancer Stage IV|Chest Tubes
Interventions: DEVICE: Seldinger chest drain insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of ABI and WIfI in Rural Health Clinics
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Diabetic Foot|Diabetes Mellitus
Interventions: BEHAVIORAL: ABI/WIFI scoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Physica TT Tibial Plate Follow up Study
Status: NOT_YET_RECRUITING
Conditions: Knee Arthropathy
Interventions: DEVICE: Device: Physica TT TIbial Plate and Physica Porous KR|DEVICE: Device: Physica TT TIbial Plate and Physica Porous PS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Window Trial to Evaluate Molecular Response to PI3K Inhibition With Copanlisib in r/r Adult B-cell ALL
Status: TERMINATED
Conditions: Leukemia, Acute Lymphocytic
Interventions: DRUG: Copanlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Salmon Fishmeal in Humans
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: Salmon fishmeal|DIETARY_SUPPLEMENT: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HD-EEG Connectivity Changes in Migraine Patients Undergoing Treatment With Anti-CGRP mAbs
Status: RECRUITING
Conditions: Migraine Disorders|Chronic Migraine|Episodic Migraine
Interventions: DRUG: Monoclonal antibody targeting the CGRP pathway (ligand or receptor) (mAbs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness of Qigong Exercise Versus Wu Dang Tai Chi Chuan in CVD Risk Individuals
Status: COMPLETED
Conditions: Cardiovascular Diseases|Risk Behavior, Health
Interventions: OTHER: Qigong Exercise|OTHER: Wu Dang Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Intravesical Chemotherapy After Diagnostic URS
Status: NOT_YET_RECRUITING
Conditions: Upper Urinary Tract Urothelial Carcinoma|Bladder Cancer
Interventions: DRUG: Intravesical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Patch Rx Technologies on Adherence to Vitamin and Trikafta Therapies in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Adherence, Medication
Interventions: DEVICE: Patch Cap|DEVICE: Patch App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With Melanoma
Status: COMPLETED
Conditions: Metastatic, Stage III or Stage IV, Melanoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Tumor-Infiltrating Lymphocytes|BIOLOGICAL: Low-Dose Interleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Atezolizumab Plus Chemotherapy After Progression on PD-1 or PD-L1 in Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Atezolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Assessing the GNbAC1 in Patients With Onset of Type 1 Diabetes Within 4 Years
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: GNbAC1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping OsteoARthritis After an ACL Tear
Status: RECRUITING
Conditions: Knee Injuries|Anterior Cruciate Ligament Rupture|Osteoarthritis, Knee
Interventions: BEHAVIORAL: Stop OsteoARthritis (SOAR) program|BEHAVIORAL: Living Well after ACLR program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dutasteride Treatment for the Reduction of Heavy Drinking in Men
Status: COMPLETED
Conditions: Alcoholism|Alcohol Abuse|Alcohol Dependence
Interventions: DRUG: Dutasteride|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
Status: RECRUITING
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Group CBT for Social Anxiety Disorder|DRUG: Sertraline|BEHAVIORAL: Individual CBT for Social Anxiety Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DilaCheck Cervical Dilation Measurement Trial
Status: COMPLETED
Conditions: Cervical Dilation|Labor Pain|Labor Fast|Labor; Irregular
Interventions: DEVICE: DilaCheck|DIAGNOSTIC_TEST: Cervical dilation examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of TIP Urethroplasty With Spongioplasty-Dartosoraphy Reinforcement in Pediatric Hypospadias
Status: COMPLETED
Conditions: Hypospadias|Complication,Postoperative
Interventions: PROCEDURE: Tubularized Incised Plate (TIP) urethroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Traditional Chinese Medicine on Outcomes in Patients With Severe Pneumonia
Status: UNKNOWN
Conditions: Community-Acquired Infections
Interventions: DRUG: TCM plus conventional drug|DRUG: TCM placebo plus conventional drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in the Evaluation of Chronic Lung Disease
Status: COMPLETED
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension|Interstitial Lung Disease
Interventions: OTHER: Blood Gas|OTHER: Pulmonary Exercise Test|OTHER: Spirometry|OTHER: Breath Condensate Collector
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Donor Peripheral Stem Cell Transplant in Treating Patients With Hematolymphoid Malignancies
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Relapsing Chronic Myelogenous Leukemia|Splenic Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on an Investigational Yellow Fever Vaccine Compared With Stamaril in Adults in Europe and Asia
Status: ACTIVE_NOT_RECRUITING
Conditions: Yellow Fever
Interventions: BIOLOGICAL: Yellow fever vaccine (produced on serum-free Vero cells)|BIOLOGICAL: Yellow fever vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Medications Review on Potentially Inappropriate Medications and Clinical Outcomes Among Hospitalized Older Adults
Status: RECRUITING
Conditions: Deprescriptions|Aged|Inappropriate Prescribing|Potentially Inappropriate Medications|Polypharmacy
Interventions: OTHER: MALPIP criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Graft Rejection|Kidney Failure|Kidney Transplant
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Scaler Tip Design on Patients' Pain Perception
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: PS (DS-016A, EMS® Piezon, Switzerland) scaler tips. )|OTHER: Conventional (FS-407, EMS® Piezon, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Short Implants - An Alternative to Bone Grafting?
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: ASTRA TECH Implant System, OsseoSpeed™ 4.0 S (length: 6 mm)|DEVICE: ASTRA TECH Implant System, OsseoSpeed™ implants (lengths: 11, 13, 15 mm) in combination with bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy
Status: COMPLETED
Conditions: HIV Infections|Peripheral Nervous System Diseases|Pain
Interventions: DRUG: Capsaicin Dermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of RNS60 on Pain and Function After Hip Labral Repair
Status: WITHDRAWN
Conditions: Hip Labral Tear
Interventions: DRUG: RNS60|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Suizenji in Patients With Unresectable Pancreatic Cancer
Status: RECRUITING
Conditions: Unresectable Pancreatic Cancer
Interventions: DEVICE: Suizenji|DRUG: Nal-IRI/FL|DRUG: mFOLFIRINOX|DRUG: Gem/nab-PTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment
Status: RECRUITING
Conditions: Dependence, Opioid
Interventions: BEHAVIORAL: Brief, values based intervention for early buprenorphine treatment|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Intervention Study With Calcium Phosphate and Vitamin D
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: calcium phosphate|DIETARY_SUPPLEMENT: vitamin d|DIETARY_SUPPLEMENT: calcium phosphate and vitamin d|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Synthetic Bone Alone Versus Synthetic Bone With Bone Marrow in Bone Lesions
Status: COMPLETED
Conditions: Bone Diseases
Interventions: DEVICE: Vitoss Alone|DEVICE: Vitoss with Bone Marrow Aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESIPI for Reducing Perioperative Major Adverse Cardiac Events
Status: TERMINATED
Conditions: Inotropy|Fluid Management|Cardiac Event|Perioperative Cardiac Risk|Vascular Resistance|Hemodynamic Monitoring|Hemodynamic Management|Fluid Responsiveness
Interventions: PROCEDURE: RESIPI Management Strategy|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Effects of High Doses Statin on Ventricular Remodeling in STEMI Patients
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: DRUG: Rosuvastatin 20 mg|DRUG: Atorvastatin 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of V520 in a HIV Vaccine Dose Refinement Study (V520-027)(TERMINATED)
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MRKAd5 HIV-1 gag/pol/nef 4 x 10^9 Ad5 vg/dose (V520)|BIOLOGICAL: MRKAd5 HIV-1 gag/pol/nef 8 x 10^9 Ad5 vg/dose (V520)|BIOLOGICAL: MRKAd5 HIV-1 gag/pol/nef 1.5 x 10^10 Ad5 vg/dose (V520)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Diagnostic Performance of of MAGENTIQ-COLO During Colonoscopy.
Status: NOT_YET_RECRUITING
Conditions: Screening Colonoscopy|Surveillance Colonoscopy
Interventions: DIAGNOSTIC_TEST: MAGENTIQ-COLO.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pericapsular Nerve Group Block for Elective Hip Arthroplasty
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: PENG Block with local anesthetic|PROCEDURE: PENG Block with 0,9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer
Status: NOT_YET_RECRUITING
Conditions: Liver Cancer
Interventions: DRUG: chidamide combined with Sintilimab and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Scan in Planning Treatment in Patients Undergoing Combination Chemotherapy For Stage IA or Stage IIA Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: RADIATION: Involved Field Radiotherapy|OTHER: No further treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxia 2: Cardiovascular and Metabolism
Status: TERMINATED
Conditions: Hypoxia|Sleep Apnea|Obstructive Sleep Apnea
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: Valsartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Transcranial Magnetic Stimulation on Dynamic Cerebral Autoregulation in Healthy Adults
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation
Interventions: PROCEDURE: 1 Hz Repetitive transcranial magnetic stimulation|PROCEDURE: 10 Hz Repetitive transcranial magnetic stimulation|PROCEDURE: Sham Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deventilation Dyspnea in COPD Patients Using NIV
Status: COMPLETED
Conditions: COPD|Dyspnea|Mechanical Ventilation Complication
Interventions: DEVICE: Monitoring physiology with Electrical Impedance Tomography, Electromyography and transcutaneous carbon dioxide measurements.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis|Erectile Dysfunction
Interventions: DRUG: Vardenafil|PROCEDURE: HVPG (Hepatic venous pressure measurement) baseline|PROCEDURE: HVPG (Hepatic venous pressure measurement) day 7|BEHAVIORAL: IIEF 5 (International Index of Erectile Function) questionaire baseline|BEHAVIORAL: IIEF 5 (International Index of Erectile Function) questionnaire at study phase end|DRUG: Placebo intake once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Primary Long Full Coverage Stenting vs Primary Short Spot Stenting for Long Femoropopliteal Artery Disease.
Status: COMPLETED
Conditions: Claudication
Interventions: DRUG: Percutaneous transluminal angioplasty of femoropopliteal artery lesions with primary long|DRUG: short stenting for the primary outcome and use of cilostazol for 12 months for secondary outcome.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Fecal Immunochemical Test in Iron Deficiency Anemia (IDAFIT)
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: Immunochemical fecal occult blood test|DEVICE: Colonoscopy|DEVICE: Upper endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Trial of Intensive Motivational Interviewing (IMI) to Improve Drinking Outcomes Among Women
Status: COMPLETED
Conditions: Alcohol Use Disorders
Interventions: BEHAVIORAL: Intensive Motivational Interviewing|BEHAVIORAL: Single session of Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard IV Cannula Aspiration (SIVCA): A Novel, Efficient and Minimally Invasive Testicular Sperm Aspiration Technique
Status: COMPLETED
Conditions: Non Obstructive Azoospermia
Interventions: DEVICE: Standard IV Cannula for aspiration of testicular sperm|PROCEDURE: Micro-TESE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 531 Treatment of Thrombocytopenic Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP) Refractory to Splenectomy
Status: COMPLETED
Conditions: Thrombocytopenia|Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Placebo|BIOLOGICAL: AMG 531
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Project 4B: Lower Extremity Strength Training in ICU Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: DEVICE: Muscle stimulation with Niveus medical stimulator|DEVICE: measurement of maximal isometric twitch strength|PROCEDURE: Muscle Biopsy|DRUG: Muscle Biopsy Medication: Lidocaine|DRUG: Muscle Biopsy Medication: Versed|DRUG: Muscle Biopsy Medication: Fentanyl|OTHER: Blood and Urine Sampling|DEVICE: ineffective muscle stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Regorafenib (Stivarga, BAY73-4506)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized Trial
Status: TERMINATED
Conditions: Retinal Vein Occlusion
Interventions: PROCEDURE: vitrectomy with radial optic neurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study of the Safety and Efficacy of Lessertia Frutescens in HIV-infected South African Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Placebo|DRUG: Low Dose|DRUG: Mid Dose|DRUG: High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions
Status: RECRUITING
Conditions: Opioid-use Disorder|Mental Health Conditions
Interventions: BEHAVIORAL: Collaborative Care for Opioid Use Disorders and Mental Health Conditions|BEHAVIORAL: Augmented Usual Care|BEHAVIORAL: Collaborative Care for Opioid Use Disorders and Mental Health Conditions Plus Certified Recovery Specialists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Registry of Patients Under Treatment With Atypical Antipsychotics
Status: COMPLETED
Conditions: Schizophrenia|Major Depressive Disorder|Bipolar Depressive Disorder|Parkinson's Disease With Hallucinations
Interventions: DRUG: Atypical Antipsychotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Sodium Oxybate|DRUG: Sodium Oxybate & 6 Tablets|DRUG: Sodium Oxybate & 8 Tablets|DRUG: Sodium Oxybate Oral Solution (6 grams)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Hypertension
Interventions: DRUG: Rosiglitazone|DRUG: Normal saline 0.9%|DRUG: Intralipid 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postmenopausal Evaluation and Risk-reduction With Lasofoxifene (PEARL)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: lasofoxifene|OTHER: placebo|DRUG: lasofoxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchial Challenge Test of Magnesium-treated Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Magnesium supplement (magnesium hydroxide/ -oxide)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis
Status: NOT_YET_RECRUITING
Conditions: Liver Steatoses|Liver Metastasis Colon Cancer|NAFLD
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: Angioplasty|PROCEDURE: Laser atherectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study
Status: UNKNOWN
Conditions: Coagulopathy During Cardiac Surgery
Interventions: DEVICE: Conventional laboratory testing (Central laboratory)|DEVICE: POC testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analgesic Treatment Mediated by Arcoxia (0663-093)
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: MK0663, Arcoxia, etoricoxib / Duration of Treatment: 3 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Independent Effects of 4-Factor Prothrombin Complex Concentrate and Tranexamic Acid on Bleeding/Pharmacodynamics in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivaroxaban|DRUG: Tranexamic acid|DRUG: Kcentra, a 4-factor PCC|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BOTOX® vs. XEOMIN® for Chronic Migraine
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: DRUG: IncobotulinumtoxinA (XEOMIN®)|DRUG: OnabotulinumtoxinA (BOTOX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pre-hospital Agitation and Sedation Trial: A Randomized Controlled Trial of Haloperidol Versus Midazolam for the Sedation of the Agitated Patient
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: Haloperidol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intercostal Cryoneurolysis Following Traumatic Rib Fractures
Status: TERMINATED
Conditions: Rib Fractures
Interventions: DEVICE: Cryoneurolysis|DEVICE: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia.
Status: ACTIVE_NOT_RECRUITING
Conditions: Transfusion Dependent Beta-Thalassaemia
Interventions: BIOLOGICAL: ET-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Diroximel Fumarate (DRF) in Adult Participants From the Asia-Pacific Region With Relapsing Forms of Multiple Sclerosis (RMS)
Status: RECRUITING
Conditions: Relapsing Forms of Multiple Sclerosis
Interventions: DRUG: Diroximel fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait in Low Back Pain Patients After Spinal Mobilization
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: TENS|PROCEDURE: spinal mobilization|PROCEDURE: swedish type massage|PROCEDURE: static hamstring stretch|PROCEDURE: sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Choline Bitartrate|OTHER: Pre-cooked, pre-peeled whole hardboiled eggs|OTHER: Egg whites from pre-cooked, pre-peeled hardboiled eggs|DIETARY_SUPPLEMENT: Phosphatidylcholine capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients
Status: RECRUITING
Conditions: Dental Phobia|Dental Anxiety|Oral Aversion
Interventions: BEHAVIORAL: Medical Play|BEHAVIORAL: Routine Play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sex-dependent Effects of Flavanols on Vascular Status
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Flavanol rich intervention|DIETARY_SUPPLEMENT: Flavanol free intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerability of an Anesthesia-free Tonometer Tip
Status: NOT_YET_RECRUITING
Conditions: Glaucoma
Interventions: DIAGNOSTIC_TEST: Sterile commercially available bandage contact lens|DIAGNOSTIC_TEST: Medical grade silicone of a thickness <100 µm|DIAGNOSTIC_TEST: Medical grade silicone of a thickness >100 µm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ToothWave Plaque and Gingivitis Study
Status: COMPLETED
Conditions: Gingivitis|Plaque|Calculus, Dental
Interventions: DEVICE: RF utilizing powered toothbrush|DEVICE: Control placebo with no RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antiemetic Efficacy of Palonosetron Versus Ondansetron for Cesarean Sections Under Regional Anesthesia
Status: COMPLETED
Conditions: PONV
Interventions: DRUG: Placebo|DRUG: Ondansetron|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the ED
Status: TERMINATED
Conditions: Acute Pain
Interventions: DRUG: Codeine|DRUG: Oxycodone|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis
Status: UNKNOWN
Conditions: Neutropenic Enterocolitis|Myeloablative Chemotherapy Induced Bone Marrow Aplasia
Interventions: PROCEDURE: Peripheral blood stem cell mobilisation and collection|DRUG: High-dose chemotherapy|DRUG: Bone marrow derived allogeneic MMSCs infusion|PROCEDURE: Autologous peripheral blood stem cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phenytoin for Memory Impairment Secondary to Megestrol
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: Phenytoin 200 mg capsule|DRUG: Megestrol 800 mg liquid|DRUG: Phenytoin-matched Placebo capsule|DRUG: Megestrol-matched liquid Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neck Grasp as a Predictor of Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Type 2 Diabetes
Interventions: OTHER: polysomnogram|OTHER: home sleep test|OTHER: Easy Sleep Apnea Predictor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Obinutuzumab, Rituximab, Polatuzumab Vedotin, and Venetoclax in Relapsed or Refractory Follicular Lymphoma (FL) or Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Rituximab|DRUG: Polatuzumab Vedotin|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute and Chronic Effects of Remote Ischemic Conditioning on Cardiovascular Function
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Brachial cuff, in order to achieve ischemic stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of an Intervention to Improve Problem List Accuracy and Use
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity|Asthma|COPD|Breast Cancer|Coronary Artery Disease|Congestive Heart Failure|Diabetes|Glaucoma|Hemophilia|Hypertension|Hyperthyroidism|Hypothyroidism|Myasthenia Gravis|Osteoporosis|Osteopenia|Renal Failure|Renal Insufficiency|Sickle Cell Disease|Stroke
Interventions: OTHER: MAPLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Benefit at 6 Months of a 3 Weeks Spa Treatment in the Type 2 Diabetic Patient.
Status: UNKNOWN
Conditions: Diabetes Mellitus|Physical Activity|Dietetic Rules|Therapeutic Education
Interventions: OTHER: SPA Treatment with therapeutic education and physical activity|OTHER: Week end
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POST-dilatation to Improve Outcomes in Acute STEMI Patients Undergoing Primary With OCT Assessment
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: post-dilatation with a Quantum Maverick balloon|DEVICE: manual thrombus aspiration + Promus Element stent implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludeoxyglucose F-18 PET/CT in Predicting Response to Chemotherapy in Patients With Stage IIIA Non-small Cell Lung Cancer That Can Be Removed by Surgery
Status: WITHDRAWN
Conditions: Stage IIIA Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Docetaxel|RADIATION: Fludeoxyglucose F-18|DRUG: Gemcitabine Hydrochloride|DRUG: Pemetrexed Disodium|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation of Fluid Strategies Using Real-time Bioelectrical Analyzer in Surgical Intensive Care Unit (SICU)
Status: COMPLETED
Conditions: Fluid Overload|Fluid Loss
Interventions: DRUG: Active fluid management with BIA monitoring|DRUG: Conventional fluid management without BIA monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Strength Training in Combination With Endurance Training on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: training|OTHER: training|OTHER: training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dovitinib With Androgen Deprivation Therapy (ADT) in Patients With Metastatic Prostate Cancer Receiving Primary ADT
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Standard ADT|DRUG: Dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maraviroc 300 mg Twice Daily in HIV Negative Male Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Maraviroc|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glove-loaded Foley's Catheter Tamponade for Cesarean Section for Placenta Previa
Status: COMPLETED
Conditions: Placenta Previa|Post Partum Hemorrhage
Interventions: PROCEDURE: A glove-loaded Foley's catheter tamponade|PROCEDURE: stepwise uterine devascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Impact of myHealth Rewards Program-related Communications on Enrollment: Replication
Status: COMPLETED
Conditions: Health Promotion|Wellness Program
Interventions: BEHAVIORAL: Email|BEHAVIORAL: Loss frame|BEHAVIORAL: Testimonial (medical expert)|BEHAVIORAL: Testimonial (rank-and-file)|BEHAVIORAL: Social norms (percentage)|BEHAVIORAL: Social norms (number)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclophosphamide and Fludarabine Followed by Cellular Adoptive Immunotherapy and Vaccine Therapy in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: Melan-A VLP vaccine, IMP321 adjuvant|BIOLOGICAL: adoptive immunotherapy|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the PK and PD of Insulin Lispro Administered Into Different Tissues in Subjects With Diabetes Mellitus Type 1
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin LISPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Doppler Ultrasound Hepatic Vein Waveform as a Non-invasive Tool in the Assessment of Severity of Portal Hypertension
Status: UNKNOWN
Conditions: Portal Hypertension
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: French Assessment of MRD by Liquid Biopsies in Colorectal With Liver Metastasis Patients (FRENCH.MRD.CRLM)
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Stage IV Colorectal Cancer|Minimal Residual Disease|Liquid Biopsy|ctDNA
Interventions: BIOLOGICAL: Blood sample/Liquid biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vitamin D Supplementation on Fasting Glucose and Interleukin-10 (IL-10) in Arab Women With Impaired Fasting Glucose
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Oral vitamin D 100,000 IU|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Tolerability of Sativex® in Patients With Neuropathic Pain.
Status: COMPLETED
Conditions: Pain|Peripheral Neuropathy
Interventions: DRUG: Sativex®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE