pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Self-administered Acupressure for Knee Osteoarthritis: A Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Self-acupressure|OTHER: Knee health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of E-health Intervention in Improving Mental Health Outcomes Among Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasms|Depression, Anxiety|Distress, Emotional
Interventions: OTHER: E-health video
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial to Assess the Continued Safety of and Adherence to a Vaginal Ring Containing Dapivirine in Women
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: COMBINATION_PRODUCT: Dapivirine Vaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Oxaliplatin, capecitabine, gemcitabine, cetuximab|DRUG: Oxaliplatin, capecitabine, gemcitabine cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Wound Protector in Whipple's Procedure With Intrabiliary Stent
Status: COMPLETED
Conditions: Surgical Wound Infection|Pancreatic Neoplasms
Interventions: DEVICE: Alexis - a wound protector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Isocaloric Time Restricted Eating on Ketone Metabolism and Immunoregulation
Status: RECRUITING
Conditions: Obesity|Body Weight
Interventions: BEHAVIORAL: Early Time-Restricted Eating|BEHAVIORAL: Conventional dietary regimen (12-hr, 9:30a-9:30p)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria
Status: ACTIVE_NOT_RECRUITING
Conditions: Phenylketonuria (PKU)
Interventions: DRUG: Pegvaliase|OTHER: Diet Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a New Post Image Processing Engine (S-Vue™) for the Reduction of Ionizing Radiation Dose on X-ray Examination in Pediatric Patients
Status: COMPLETED
Conditions: Chest X-ray for Clinical Evaluation
Interventions: DIAGNOSTIC_TEST: Full Dose Chest X-Ray|DIAGNOSTIC_TEST: Low Dose Chest X-Ray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Ileostomy Closure for Rectal Cancer Patients in North America
Status: RECRUITING
Conditions: Ileostomy - Stoma|Rectal Cancer
Interventions: PROCEDURE: Early Ileostomy Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Architecture in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Foot Deformities|Muscle Weakness|Kinesiophobia
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Welchol as Monotherapy for Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Welchol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Active Systemic Lupus Erythematosus
Interventions: DRUG: Efavaleukin Alfa|DRUG: Placebo|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omalizumab in Non-atopic Asthma
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: 70 mg SC|DRUG: 210 mg SC|DRUG: 140 mg SC|DRUG: 280 mg SC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: SPRC-AB01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Alpha-Lipoic Acid Ingestion on Glucose Tolerance in Subjects With Pre-Diabetes
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: alpha lipoic acid|DIETARY_SUPPLEMENT: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Depression and Positive Parenting Techniques (ADAPT)
Status: RECRUITING
Conditions: Depression|Emotional Problem|Disruptive Behavior Disorder|Attention Deficit Hyperactivity Disorder|Conduct Disorder|Oppositional Defiant Disorder|Behavior Problem
Interventions: BEHAVIORAL: Addressing Depression and Positive Parenting Techniques (ADAPT) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CAP-1 Trial: Stepwise Excavation Versus One Completed Excavation in Deep Caries
Status: COMPLETED
Conditions: Dental Caries|Reversible Pulpitis
Interventions: PROCEDURE: SW|PROCEDURE: DCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Downstream Versus Upstream Strategy for the Administration of P2Y12 Receptor Blockers
Status: UNKNOWN
Conditions: Unstable Angina or Non ST Elevated Myocardial Infarction
Interventions: PROCEDURE: Downstream strategy|PROCEDURE: Upstream strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Pulsatile Intravenous (IV) Insulin on Wound Healing in Diabetics
Status: TERMINATED
Conditions: Wound Healing|Diabetes
Interventions: PROCEDURE: Pulsatile Intravenous Insulin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combining Aprepitant With Ondansetron in High-risk Patients for Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Remifentanil|PROCEDURE: Cold pain threshold and tolerance|DEVICE: Heat pain threshold and tolerance|PROCEDURE: Polysomnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
Status: NOT_YET_RECRUITING
Conditions: Cardiomyopathy, Hypertrophic|Cardiomyopathy, Dilated|Cardiomyopathy Restrictive|Arrhythmogenic Right Ventricular Dysplasia|Non-Compaction Cardiomyopathy|Familial Hypercholesterolemia|Marfan Syndrome|Ehlers-Danlos Syndrome, Vascular Type|Loeys-Dietz Syndrome|Long QT Syndrome|Short Qt Syndrome|Brugada Syndrome|Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions: DIAGNOSTIC_TEST: whole genome sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of MD1003 in Progressive Multiple Sclerosis (SPI2)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: MD1003 100mg capsule|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants Without Inhibitors
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab|DRUG: Factor VIII (FVIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Microfluidic Separation Sperm Selection for Unexplained Infertility and Reccurrent Implantation Failure
Status: UNKNOWN
Conditions: Unexplained Infertility|Recurrent Implantation Failure
Interventions: PROCEDURE: Sperm Chip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Upper Extremities
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of Rituximab, Cyclophosphamide, Doxorubicin, VELCADE, and Prednisone or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Rituximab 375 mg/m^2|DRUG: Cyclophosphamide 750 mg/m^2|DRUG: Doxorubicin 50 mg/m^2|DRUG: VELCADE 1.3 mg/m^2|DRUG: Prednisone 100 mg/m^2|DRUG: Vincristine 1.4 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Esophageal Variceal Rebleeding
Status: UNKNOWN
Conditions: Esophageal Variceal Rebleeding
Interventions: DRUG: terlipressin (vasoconstrictor)|DRUG: pantoloc (proton pump inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Acceptability/Swallowability of DRV-Containing FDC Tablets in HIV-1 Infected Adolescents, Using Matching Placebo Tablets
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: DRV/COBI FDC placebo tablet|DRUG: D/C/F/TAF FDC placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brace Treatment for Idiopathic Scoliosis; PReventing Idiopathic SCOliosis PROgression
Status: RECRUITING
Conditions: Idiopathic Scoliosis
Interventions: DEVICE: 3D TLSO|DEVICE: Standard TLSO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
Status: WITHDRAWN
Conditions: Anesthesia|Pain|Child
Interventions: DRUG: Remifentanil|DEVICE: Pupillometry|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxycodone or Standard Pain Therapy in Treating Patients With Cancer Pain
Status: COMPLETED
Conditions: Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: acetaminophen|DRUG: codeine phosphate|DRUG: dextropropoxyphene hydrochloride|DRUG: morphine sulfate|DRUG: oxycodone hydrochloride|PROCEDURE: management of therapy complications|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome
Status: COMPLETED
Conditions: Cachexia|HIV Infections|HIV Wasting Syndrome
Interventions: DRUG: Dronabinol|DRUG: Megestrol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of The Post-Extraction Dimensional Alterations Following Ridge Preservation Using Autogenous Partially and Completely Demineralized Dentin Grafts Versus Autogenous Whole-tooth Graft
Status: NOT_YET_RECRUITING
Conditions: Socket Preservation, Alveolar Ridge Deficiency, Alveolar Ridge Preservation
Interventions: PROCEDURE: Alveolar ridge preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AutologousCD22 Chimeric Antigen Receptor (CAR)T Cells in w/Recurrent/Refractory B Cell Lymphomas
Status: RECRUITING
Conditions: Follicular Lymphoma|Mantle Cell Lymphoma|Hairy Cell Leukemia|Lymphoplasmacytic Lymphoma|Burkitt Lymphoma|Marginal Zone Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: CD22CART Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosing Extremity Fractures and/or Dislocations Using Ultrasound Presenting to the Emergency Department
Status: TERMINATED
Conditions: Fractures|Dislocations
Interventions: PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using the Composite Immune Risk Score to Assess and Modulate the Patient's Post-transplant Immune Reconstitution.
Status: RECRUITING
Conditions: Transplant-Related Disorder
Interventions: BEHAVIORAL: Health monitoring and regular return follow-up reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Two Formulations of Pregabalin CR(Controlled-release) Table 300 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLA5PR GLARS-NF3 tablet 300mg|DRUG: GLA5PR GLARS-NF1 tablet 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Therapeutic Vaccine Based on aDC1 Dendritic Cells for the Control of Viremia After ATI in HIV Infected Individuals
Status: NOT_YET_RECRUITING
Conditions: HIV Vaccine
Interventions: BIOLOGICAL: Alpha-type-1 Polarizing Dendritic Cells (aDC1) unpulsed with HIV peptides|BIOLOGICAL: Alpha-type-1 Polarizing Dendritic Cells (aDC1) pulsed with HIV peptides|OTHER: Commercial ringer´s lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorder
Interventions: DRUG: Duloxetine|DRUG: venlafaxine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety and Immune Response of an Influenza Vaccine Made by a New Manufacturing Process With a Vaccine Made by the Traditional Manufacturing Process for Season 2003/2004
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vero Cell-derived Influenza Vaccine|BIOLOGICAL: Egg-derived Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Melissa Officinalis for the Treatment of Probable Sleep Bruxism in Children and Adolescents
Status: RECRUITING
Conditions: Sleep Bruxism|Adolescent|Children|Temporomandibular Joint Disorders
Interventions: DRUG: Melissa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Effectiveness of the Model of Centered Care in the Person in the Geriatric Population at Home(Project AICP.Com)
Status: SUSPENDED
Conditions: Geriatric Care
Interventions: OTHER: MAICP + usual care of social services|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Volume Controlled Ventilation and Pressure Controlled Ventilation in Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery
Interventions: PROCEDURE: volume-controlled ventilation|PROCEDURE: pressure-controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Use of Mometasone Eluting Stent in Choanal Atresia
Status: WITHDRAWN
Conditions: Choanal Atresia
Interventions: DRUG: Drug-eluting Stent Mometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Alpha-lipoic Acid in Diabetes Melitus Type 1
Status: NOT_YET_RECRUITING
Conditions: Diabetes MellitusType 1
Interventions: OTHER: Placebo|DRUG: Alpha Lipoic Acid 600 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Survival in Patients With Severe Alcoholic Hepatitis Treated With Steroid Versus Pentoxifylline
Status: UNKNOWN
Conditions: Alcoholic Hepatitis
Interventions: DRUG: pentoxifylline|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 mg/40 mg
Status: COMPLETED
Conditions: PAH
Interventions: DRUG: Macitentan and Tadalafil|DRUG: PrOpsynvi® Film-Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
Status: COMPLETED
Conditions: Constipation|Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: Polydextrose|DIETARY_SUPPLEMENT: placebo-controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ketoconazole Inhibition of CYP3A on Urinary Excretion of Docetaxel
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Docetaxel|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Age of OrthoInfo: A Randomized Controlled Trial Evaluating Patient Comprehension of Informed Consent in a Private Practice
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Model|BEHAVIORAL: Knee Anatomy Video|BEHAVIORAL: Verbal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2979165 and LY2140023 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2979165|DRUG: LY2140023|OTHER: Placebo|OTHER: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Acupuncture and Fu's Subcutaneous Needling (FSN ) in Treating Chronic Tension-type Headache by fMRI
Status: UNKNOWN
Conditions: Chronic Tension-Type Headache
Interventions: DEVICE: Acupuncture|DEVICE: Fu's Subcutaneous Needling (FSN)|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Unidas Por la Vida: A Healthy Lifestyle Intervention for High-risk Latina Dyads
Status: COMPLETED
Conditions: Diabetes|Obesity|Overweight
Interventions: BEHAVIORAL: Dyadic lifestyle intervention|BEHAVIORAL: Individual lifestyle intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: JS010 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Revumenib in Combination With 7+3 + Midostaurin in AML
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|AML, Adult|AML With Gene Mutations|AML|Leukemia
Interventions: DRUG: Revumenib|DRUG: Midostaurin|DRUG: Cytarabine|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer-led and Telehealth Comparative Effectiveness Research (CER) Adoption for Diabetes Prevention and Management
Status: UNKNOWN
Conditions: Diabetes|Pre-diabetes
Interventions: BEHAVIORAL: Peer-led intervention|BEHAVIORAL: Telehealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Medullary Thyroid Cancer
Interventions: DRUG: Selpercatinib|DRUG: Cabozantinib|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Dose-Escalation Study With ETI-204 in Adult Volunteers
Status: COMPLETED
Conditions: Inhalational Anthrax
Interventions: BIOLOGICAL: ETI-204|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Colchicine's Efficacy in MI Patients: Comparing PCI and Non-Reperfusion Approaches
Status: COMPLETED
Conditions: ST-Elevation Myocardial Infarction
Interventions: DRUG: Colchicine 0.5 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Bowel Preparation in Virtual Colonoscopy (VC) - Patient Experience
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: bowel preparation: senna & gastrofin versus picolax (standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Relative Bioavailability and Bioequivalence of Opicapone
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Ongentys|DRUG: BIA 9-1067 (test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 151 Amgen Protocol Number 20100761
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: AMG 151|DRUG: Placebo|DRUG: Metformin|DRUG: AMG 151|DRUG: AMG 151|DRUG: AMG 151|DRUG: AMG 151|DRUG: AMG 151
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukaemia, Lymphocytic, Chronic
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acyclovir in Combination With a Glucocorticosteroid on UV-Induced Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: ME-609|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rigosertib for RDEB-SCC
Status: RECRUITING
Conditions: Epidermolysis Bullosa Dystrophica|Squamous Cell Carcinoma
Interventions: DRUG: Rigosertib Oral Capsules / Rigosertib Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Central Venous-arterial Carbon Dioxide Difference
Status: COMPLETED
Conditions: Jugular Veins|Radial Artery|Carbon Dioxide
Interventions: DRUG: Goal-directed fluid therapy (GDET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficiency of Two Different PPI Formula in Atypical GERD
Status: UNKNOWN
Conditions: Compare the Response Rate of Atypical GERD After PPI Therapy
Interventions: DRUG: dexilansoprazole (Dexilant 60 mg)|DRUG: lansoprazole (Takepron OD 30 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aerobic Exercise Associated With Abdominal Laser Therapy
Status: TERMINATED
Conditions: Metabolic Disease
Interventions: DEVICE: Low level laser therapy|DEVICE: Aerobic Exercise|DEVICE: Low level laser therapy without power
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Efficacy of PADN to Improved Functional Capacity and Hemodynamics in Patients With PAH
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: PADN|PROCEDURE: sham PADN|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Soy and Daidzein on Reduction of Blood Pressure in Postmenopausal Chinese Women
Status: UNKNOWN
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Whole soy (soy flour)|DIETARY_SUPPLEMENT: daidzein|DIETARY_SUPPLEMENT: milk powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Phase II Study to Evaluate the Efficacy and Safety of IdeS in Anti-GBM Disease
Status: COMPLETED
Conditions: Anti-Glomerular Basement Membrane Antibody Disease
Interventions: BIOLOGICAL: Imlifidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic and Cardiac Metabolic Flexibility in Obese With NAFLD.
Status: COMPLETED
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness and Safety of Convalescent Plasma in Patients With High-risk COVID-19
Status: UNKNOWN
Conditions: Sars-CoV2|Covid-19
Interventions: BIOLOGICAL: SARS-CoV-2 convalescent plasma treatment|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Line Treatment Trial in Multiple Myeloma, Finnish Myeloma Group- Multiple Myeloma 02
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REGAIN: RCT of Oxaloacetate for Fatigue in Long COVID
Status: RECRUITING
Conditions: Post-COVID-19 Syndrome|Fatigue Syndrome, Chronic
Interventions: OTHER: Anhydrous Enol-Oxaloacetate, a "Medical Food"|OTHER: White Rice Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ivabradine in the Management of Cardiac Autonomic Dysfunction Associated With Thoracic Radiation Therapy.
Status: TERMINATED
Conditions: Lymphoma|Autonomic Imbalance|Cancer Survivorship
Interventions: DRUG: Ivabradine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Status: RECRUITING
Conditions: CVA (Cerebrovascular Accident)|Stroke|Upper Extremity Paresis
Interventions: BEHAVIORAL: Grade 2-5 CI Therapy + Sensory Components
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion
Status: ACTIVE_NOT_RECRUITING
Conditions: Erythroplakia|Hyperplasia|Oral Cavity Carcinoma|Oral Leukoplakia
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of N-Acetyl Cysteine (NAC) on the Oral Microbiome
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DRUG: N-Acetyl-L-Cysteine dietary supplement|RADIATION: Chemotherapy and Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound-guided Regional Anesthesia vs Local Infiltration Anesthesia With Dexmedetomidine and Ropivacaine
Status: COMPLETED
Conditions: Pain, Postoperative|Anesthesia, Local|Gonarthrosis
Interventions: DRUG: Ultrasound guided regional anesthesia|DRUG: Local infiltration analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Integrated Self-Management Intervention for Adolescents With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS
Interventions: BEHAVIORAL: Working to Optimize Wellness in Tees with PCOS (WOW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair
Status: COMPLETED
Conditions: Primary Unilateral Inguinal Hernia
Interventions: PROCEDURE: Group A will undergo laparoscopic TEP inguinal hernia repair with 3 ports (10 mm , and 2 ports of 5 mm )|PROCEDURE: Group B will undergo laparoscopic TEP inguinal hernia repair with a single port
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy for Anxiety Disorders in PD
Status: COMPLETED
Conditions: Parkinson's Disease|Generalized Anxiety Disorder|Social Phobia
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|OTHER: Clinical monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC
Status: UNKNOWN
Conditions: Tislelizumab|Safety|Biomarker|Chemotherapy
Interventions: DRUG: Tislelizumab 200 mg|DRUG: Carboplatin AUC 5|DRUG: pemetrexed 500mg/m2|DRUG: Paclitaxel 175mg/m2|DRUG: Nab-paclitaxel 260 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Multimodal Monitoring for Ultrasound Guided Peripheral Nerve Blockade
Status: UNKNOWN
Conditions: Orthopedic Surgery
Interventions: PROCEDURE: Manual measurement|PROCEDURE: Measurement with a gauge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development and Testing of an Interprofessional, Person-centered Care Concept for People Living at Home With Care Needs.
Status: WITHDRAWN
Conditions: Utilization of Nursing, Medical and Therapeutical Care of People Living at Home With Care Needs
Interventions: OTHER: interprofessional, person-centered care concept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Trial to Compare a Liquid-frozen and a Freeze-dried Formulation of IMVAMUNE (MVA-BN®) Smallpox Vaccine in Vaccinia-naïve Healthy Subjects
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: LF formulation of IMVAMUNE®|BIOLOGICAL: FD formulation of IMVAMUNE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mi-thos® Transcatheter Mitral Valve Replacement(First-in-Man Study)
Status: COMPLETED
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: Mi-thos® Transcatheter Mitral Valve Replacement System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Esketamine(Continuous infusion)|DRUG: Remifentanil (Target-Controlled Infusion)|DRUG: Flurbiprofen (Single intravenous injection)|DEVICE: Spinal Cord Stimulation|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Micafungin Salvage Mono-therapy in Invasive Aspergillosis
Status: TERMINATED
Conditions: Invasive Aspergillosis
Interventions: DRUG: Micafungin|DRUG: Systemic antifungal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Pharmacokinetics/Pharmacodynamic Study of L-Dopa/Carbidopa To Treat Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: levodopa-carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Brain and Peripheral Nerve Stimulation for Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Active tDCS|OTHER: Active PNS|OTHER: Sham tDCS|OTHER: Sham PNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Determine Tumor Response Using Fluorodeoxyglucose (FDG)- Positron Emission Tomography (PET)/Computed Tomography (CT) Before and After Cetuximab in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell
Interventions: PROCEDURE: FDG-PET/CT|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lanreotide In Polycystic Kidney Disease Study
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD
Interventions: DRUG: Lanreotide|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections
Status: COMPLETED
Conditions: Skin Diseases, Bacterial
Interventions: DRUG: Tigecycline|DRUG: ampicillin-sulbactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Intralipid, 20% Intravenous Emulsion|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of IV Rigosertib in MDS Patients With Excess Blasts Progressing After Azacitidine or Decitabine
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Refractory Anemia With Excess Blasts|Chronic Myelomonocytic Leukemia|Cytopenia
Interventions: DRUG: rigosertib sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Status: UNKNOWN
Conditions: Unilateral Cleft Lip
Interventions: PROCEDURE: Autogenous fat injection|PROCEDURE: Surgical revision with orbicularis oris muscle reconstruction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of the Balano-preputial Furrow 's Microbiota, in Circumcised Patients or Not, in the Acquisition or Transmission of HIV
Status: UNKNOWN
Conditions: HIV Infection
Interventions: OTHER: mucocutaneous sampling by swab at the balano-preputial furrow.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: THIODERM ELATE for Augmentation of Very Thin, Thin, and Moderately Thick Lips
Status: ACTIVE_NOT_RECRUITING
Conditions: Lip Abnormality
Interventions: DEVICE: Thioderm Elate|DEVICE: Juvéderm Ultra 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cystoscopy and Hexyl 5-Aminolevulinate in Detecting Carcinoma In Situ in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: hexaminolevulinate|PROCEDURE: biopsy|PROCEDURE: cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of JTT-851 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: JTT-851|DRUG: Glimepiride|DRUG: Placebo for Active|DRUG: Placebo for comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of ON 01910.Na as a 3-day Infusion in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Solid Tumors|Cancer|Neoplasms
Interventions: DRUG: rigosertib sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Administration to Preterm Infants
Status: COMPLETED
Conditions: Infant, Newborn
Interventions: DRUG: Darbepoetin Alfa Injection|DRUG: erythropoietin alfa injection|DRUG: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of oAncreatic Enzyme ReplAcement Therapy (PERT) on Mucosal Visibility Before Upper GI Endoscopy
Status: RECRUITING
Conditions: Upper Gastrointestinal Endoscopy
Interventions: DIAGNOSTIC_TEST: Test group|DIAGNOSTIC_TEST: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of How Tutin and Hyenanchin, Two Toxins Found in Honey, Are Absorbed and Processed by the Body
Status: COMPLETED
Conditions: Tutin Poisoning
Interventions: OTHER: Honey substance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Histological Confirmation of Clinical Clearance of Actinic Keratoses Following Treatment With Ingenol Mebutate Gel, 0.05%
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate gel 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Isoforms of Vitamin D Supplements for Infants
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol (D3) or ergocalciferol (D2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Workplace Intervention to Reduce Sitting Time: a Randomized Clinical Trial.
Status: RECRUITING
Conditions: Sedentary Behavior|Office Workers
Interventions: BEHAVIORAL: Computer prompt "Stand up for your Health®"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Bimatoprost in the Treatment of Men With Androgenic Alopecia
Status: COMPLETED
Conditions: Alopecia|Alopecia, Androgenetic|Baldness
Interventions: DRUG: bimatoprost Formulation A|DRUG: bimatoprost Formulation B|DRUG: bimatoprost Formulation C|DRUG: bimatoprost vehicle solution|DRUG: minoxidil 5% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Docetaxel Plus Cisplatin as First-line Chemotherapy in Metastatic Salivary Gland Cancer Patients : a Multicenter Phase II Study
Status: UNKNOWN
Conditions: Salivary Gland Cancer
Interventions: DRUG: docetaxel plus Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics of JNJ-42396302, JNJ-53773187 and JNJ-42692507 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42396302|DRUG: JNJ-42692507|DRUG: JNJ-53773187
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Superiority Effect of Desmopressin to Placebo in Terms of Night Voids Reduction in Nocturia Adult Female Patients
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Desmopressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Different Administration Routes of Pediatric Premedication
Status: UNKNOWN
Conditions: Anesthesia
Interventions: OTHER: Oral administration|OTHER: Intramuscular injection|OTHER: Rectal perfusion|OTHER: Dripping nose|DRUG: Anesthesia induction(midazolam,fentanyl,propofol,atracurium)|PROCEDURE: Intubation|DRUG: Anesthesia maintenance(midazolam,fentanyl,propofol,atracurium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose of Etomidate and Adrenal Cortex
Status: COMPLETED
Conditions: Adrenocortical Deficiency|Hemodynamic Instability
Interventions: DRUG: Etomidate|DRUG: Midazolam|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Image Fusion of Preprocedural CTA With Real Time Fluoroscopy to Enhance EVAR Repair
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm (AAA)
Interventions: PROCEDURE: Using pre-procedural CTA to guide advanced EVAR procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Kalifilcon A Toric Compared to Commercially Available Lenses
Status: COMPLETED
Conditions: Refractive Ametropia
Interventions: DEVICE: Kalifilcon Toric Lens|DEVICE: Total1 for Astigmatism|DEVICE: Precision1 for Astigmatism|DEVICE: MyDay Toric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT