pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endothelial Modulation for Angiogenic Therapy
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: GENETIC: intramyocardial VEGF angiogenesis (at a dose of 2 mg)|DRUG: oral L-arginine supplementation (at a dose of 6 g/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Systemic Therapy and Cognitive Behavioral Therapy for Social Anxiety Disorders
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Systemic Therapy for Social Anxiety Disorder|BEHAVIORAL: Cognitive Behavioral Therapy for Social Anxiety Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Status: COMPLETED
Conditions: Hip Fracture|Analgesia|Acute Pain
Interventions: PROCEDURE: fascia iliaca block|PROCEDURE: percapsular nerve group block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents
Status: COMPLETED
Conditions: Anterior Cruciate Ligament (ACL) Tear
Interventions: DRUG: Single-injection sciatic PNB|DRUG: Continuous sciatic PNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LAVA TQ Doppler Functionality Study
Status: COMPLETED
Conditions: Traumatic Hemorrhage
Interventions: DEVICE: Layperson Audiovisual Assist Tourniquet (LAVA TQ)|DEVICE: Combat Application Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Wound Healing: Total Contact Cast Vs. Custom-Made Temporary Footwear for Patients With Diabetic Foot Ulceration
Status: UNKNOWN
Conditions: Neuropathic Foot Ulceration in Individuals With Diabetes
Interventions: DEVICE: cast vs. shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery
Status: RECRUITING
Conditions: Bone Loss
Interventions: DRUG: Risedronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Splenectomy in Children
Status: COMPLETED
Conditions: Laparoscopic Splenectomy|Children|Benign Blood Diseases
Interventions: OTHER: laparoscopic splenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravitreal Triamcinolone Acetonide Versus Laser for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Standard of Care Group|DRUG: 1mg triamcinolone acetonide|DRUG: 4mg triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reserpine for the Treatment of Cocaine Dependence - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: Reserpine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Recovery and Postoperative Nausea and Vomiting After Middle Ear Surgeries
Status: UNKNOWN
Conditions: Treatment Complication
Interventions: DEVICE: acupuncture needles|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Ranibizumab and Bromfenac for Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: combination ranibizumab + bromfenac|DRUG: ranibizumab injection alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of a Computer-Based Colorectal Cancer Screening Decision Aid
Status: COMPLETED
Conditions: Colorectal Cancer|Health Literacy
Interventions: BEHAVIORAL: CHOICE decision aid|BEHAVIORAL: YourMeds patient education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Percutaneous Ketamine Versus Lidocaine or Placebo, for Post-Surgery Analgesia, in Patients Undergoing Laparoscopic Partial Lung Resection
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: lidocaine|DRUG: ketamine|DRUG: non-active drug cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if Shock Wave Therapy Applied to Traumatic Wounds of the Extremity Improves Healing Time
Status: UNKNOWN
Conditions: Soft Tissue Injuries
Interventions: DEVICE: DermaGold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADJUnct Semaglutide Treatment in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Related to Thrombosis in Patients With Newly Diagnosed Multiple Myeloma Receiving Chemotherapy
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Neoplasm|Thromboembolism
Interventions: OTHER: enzyme-linked immunosorbent assay|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection
Status: COMPLETED
Conditions: Plasmodium Falciparum|Malaria
Interventions: BIOLOGICAL: Exposure to Plasmodium falciparum infected mosquitoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of GLP-1 in Satiety Perception in Humans
Status: WITHDRAWN
Conditions: Appetite Regulation|Obesity
Interventions: DRUG: Exendin-(9-39) Acetate|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Mobilization With Movement on Conditioned Pain Modulation in Chronic Low Back Pain Patients
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: BIOLOGICAL: Mobilization with movement|BIOLOGICAL: Sham mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism
Status: COMPLETED
Conditions: Acute Pulmonary Embolism
Interventions: DRUG: Recombinant Human Prourokinase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Application of Pulsed Electromagnetic Field in the Treatment of Postoperative Delayed Union
Status: COMPLETED
Conditions: Fracture|Delayed Union of Fracture
Interventions: DEVICE: pulsed electromagnetic field|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Status, Maternal Depressive Symptoms, and Mother-child Interactions
Status: WITHDRAWN
Conditions: Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Iron|DIETARY_SUPPLEMENT: Gelatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage
Status: RECRUITING
Conditions: Intraventricular Hemorrhage of Prematurity
Interventions: COMBINATION_PRODUCT: MLT+EPO|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Lidocaine to Prevent Cough at Emergence From Anesthesia
Status: UNKNOWN
Conditions: Cough, General Anesthesia, Extubation, Lidocaine, Sore Throat
Interventions: DRUG: Lidocaine 2%|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study to (1) Compare How BI 456906 is Taken up in the Body of Healthy People and People With Liver Problems and (2) Find Out How People With Overweight and Obesity, With and Without Liver Problems, Tolerate Different Doses of BI 456906
Status: COMPLETED
Conditions: Healthy|Liver Diseases|Obesity
Interventions: DRUG: BI 456906
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZIKA Vaccine in Naive Subjects
Status: COMPLETED
Conditions: Zika Virus Infection
Interventions: DRUG: Saline|BIOLOGICAL: Zika Virus Purified Inactivated Vaccine (ZPIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Chlorthalidone|DRUG: Bumetanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Weekly Genexol®-PM Plus Gemcitabine in Subjects With Recurrent and Metastatic Adenocarcinoma of the Pancreas
Status: UNKNOWN
Conditions: Recurrent Adenocarcinoma of the Pancreas|Metastatic Adenocarcinoma of the Pancreas
Interventions: DRUG: Genexol-PM|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Safety Study for Compound to Treat Post-Operative Nausea and Vomiting (PONV)
Status: COMPLETED
Conditions: Post-Operative Nausea and Vomiting (PONV)
Interventions: DRUG: GW597599|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Monthly Ibandronate in Women With RA and Reduced Bone Mineral Density Receiving Long-term Steroids
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoporosis|Osteopenia
Interventions: DRUG: Ibandronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of an mHealth Colorectal Cancer Screening Intervention
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: mCRC intervention|BEHAVIORAL: Healthy Lifestyles video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anterior Advantage With KINCISE
Status: TERMINATED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post Traumatic Arthritis
Interventions: DEVICE: KINCISE(TM) Surgical Automated System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Trunk and Upper Extremity Exercises Added to the Otago Exercise Program
Status: NOT_YET_RECRUITING
Conditions: Geriatrics|Balance|Exercise|Fall Prevention
Interventions: BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Daily Supplementation of Lactobacillus Acidophilus MPH734, for One Week, Affect Acute (Immediate), Subacute (7 Days), and Post-treatment Discontinuation Lactose Metabolism, Gastrointestinal Symptoms, and Clinical Markers of Inflammation and Safety Compared to a Placebo
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: DIETARY_SUPPLEMENT: Lactobacillus acidophilus MPH734|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methylprednisolone|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Using HPPH in Treating Patients With Dysplasia, Cancer in Situ, or Invasive Cancer of the Larynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: HPPH|PROCEDURE: laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of VLTS-589 in Subjects With Intermittent Claudication
Status: COMPLETED
Conditions: Intermittent Claudication|Peripheral Vascular Disease
Interventions: GENETIC: Plasmid based Gene Transfer product-VLTS-589
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A New Treatment for Zenker's Diverticulum-submucosal Tunneling Endoscopic Septum Division
Status: UNKNOWN
Conditions: Zenker Diverticulum
Interventions: PROCEDURE: Submucosal tunneling endoscopic septum division
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia|Invasive Cervical Cancer
Interventions: DRUG: Fenofibrate|PROCEDURE: Cervical Conization|PROCEDURE: Hysterectomy|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough
Status: ENROLLING_BY_INVITATION
Conditions: Refractory Chronic Cough
Interventions: DRUG: HRS-2261 oral tablet|DRUG: Matching placebo to HRS-2261
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Experience Sharing and Mutual Assistance on Insight and Recovery During the First Psychotic Episode
Status: RECRUITING
Conditions: Psychotic Episode
Interventions: OTHER: Insight Scale|OTHER: Semi-directional interviews|OTHER: routine care|OTHER: session of mutual assistance with a mediator psychologist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-emptive Cycline Treatment on Cetuximab Induced Skin Toxicity in Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer Metastatic|Skin Toxicity
Interventions: DRUG: Doxycycline|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three Different Pulp Capping Materials in Indirect Pulp Treatment of Primary Teeth
Status: COMPLETED
Conditions: Deep Caries
Interventions: OTHER: Biodentine|OTHER: TheraCal LC|OTHER: Calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PCI-32765 for Special Cases of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Leukemia, Lymphocytyc|CLL (Chronic Lymphocytic Leukemia)|SLL (Small Lymphocytic Lymphoma)
Interventions: DRUG: PCI 32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Butyricicoccus Pullicaecorum in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Butyricicoccus pullicaecorum 25-3T|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subthalamic Nucleus Electrical Stimulation for Drug-resistant Focal Motor Epilepsy
Status: RECRUITING
Conditions: Epilepsy, Drug Resistant
Interventions: DEVICE: STN-DBS ON|DEVICE: STN-DBS OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Repeat Doses of GSK2982772 in Subjects With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: GSK2982772|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Optimal Mask Ventilation Mode in Pediatrics Using Real-time Ultrasonography
Status: UNKNOWN
Conditions: Ventilator Lung|Ultrasound
Interventions: OTHER: Peep 5cmH2O|OTHER: Peak inspiratory pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reminders, Cost Sharing, and Healthcare Use
Status: COMPLETED
Conditions: Health Care Utilization|Health Care Seeking Behavior|Health Behavior
Interventions: OTHER: Reminder (information letter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: S0119: Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Concept of the Autoantibodies Directed Against the Neuropeptides Involved in Food Intake Regulation on the Incidental Cases of Eating Disorders
Status: UNKNOWN
Conditions: Eating Disorder
Interventions: OTHER: Evaluation of the rates of the autoantibodies directed against the neuropeptides (ghrelin and alpha-MSH) controlling involved in food intake regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: New Jersey Healthcare Essential Worker Outreach and Education Study - Testing Overlooked Occupations
Status: COMPLETED
Conditions: Covid19|Health Care Seeking Behavior|Health Behavior
Interventions: BEHAVIORAL: Healthcare Worker Focused Outreach|BEHAVIORAL: Community Organization Led Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Bendamustine/Rituxan Induction Chemotherapy With Revlimid Maintenance for Relapsed/Refractory CLL and SLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Late Phase 2 Study of DU-176b in Patients With Non-Valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: DU-176b tablets|DRUG: Warfarin potassium tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Green Banana Peel Extract for Stasis Dermatitis Treatment
Status: COMPLETED
Conditions: Stasis Dermatitis
Interventions: BIOLOGICAL: Placebo comparator|BIOLOGICAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Twelve Week Safety and Efficacy Study in Rosacea
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: omiganan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Misoprostol Prior to Intrauterine Contraceptive Device Insertion
Status: COMPLETED
Conditions: Pain Prior to IUD Insertion
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Status: NOT_YET_RECRUITING
Conditions: Critical Illness|Sarcopenia|ICU Acquired Weakness
Interventions: COMBINATION_PRODUCT: MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Lymphoma|Neuroblastoma|Hepatoblastoma|Retinoblastoma
Interventions: BIOLOGICAL: GM-CSF|BIOLOGICAL: G-CSF|BIOLOGICAL: GM-CSF and G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complications After Lower Third Molar Surgery
Status: COMPLETED
Conditions: Postoperative Complications|Third Molar
Interventions: PROCEDURE: Lower third molar surgery|DRUG: Amoxicillin 500 Mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anesthesia-handover Checklist and Perioperative Outcomes in Elderly
Status: UNKNOWN
Conditions: Elderly Patients|Major Surgery|Anesthesia; Adverse Effect|Prevention|Postoperative Complications
Interventions: PROCEDURE: Oral handover|PROCEDURE: Checklist handover
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: Kenalog with bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dried Plum on Bone and Markers of Bone Status in Men
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia
Interventions: DIETARY_SUPPLEMENT: dried plum|DIETARY_SUPPLEMENT: Calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness Of Different Remineralizing Strategies on The Management Of Early Carious Lesions In Primary Teeth
Status: ACTIVE_NOT_RECRUITING
Conditions: White Spot Lesion
Interventions: DRUG: self assmbling peptide p11-4 combined with 0.05% fluoride|DRUG: Casein phosphopeptide amorphous calcium phosphate|DRUG: 5% sodium fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Active DBS|DEVICE: Sham DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prophylactic Role of Tranexamic Acid in High Risk Pregnant Women Undergoing Elective Cesarean Section in Prevention of Postpartum Hemorrhage
Status: COMPLETED
Conditions: High Risk Pregnant Women Undergoing Elective Cesarean Section
Interventions: DRUG: Tranexamic acid (Kapron, Amoun Pharmaceuticals SAE, Egypt. 5ml Amp, 100mg /1ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: High-Dose Versus Standard-Dose Oseltamivir to Treat Severe Influenza and Avian Influenza
Status: COMPLETED
Conditions: Influenza|Avian Influenza|Severe Influenza
Interventions: DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors
Status: RECRUITING
Conditions: Acneiform Eruption Due to Chemical|Xerosis Cutis|Paronychia
Interventions: DRUG: HT-001 2% Topical Gel|DRUG: HT-001 1% Topical Gel|DRUG: HT-001 0.5% Topical Gel|DRUG: HT-001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Prednisolone Dosing in Children Hospitalized With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Prednisolone high dose|DRUG: Prednisolone lower dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress and Apoptosis of Energy Metabolism by Deferiprone From the Circulating Lymphocytes
Status: COMPLETED
Conditions: Parkinson's Disease|Amyotrophic Lateral Sclerosis|Oxidative Stress|Iron Overload
Interventions: DRUG: deferiprone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Platinum-resistant Ovarian Cancer|Fallopian Tube Cancer|Epithelial Ovarian Cancer|Ovarian Cancer|Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: Pegylated Liposomal Doxorubicin + SL-172154|DRUG: Mirvetuximab + SL-172154
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Mi2000 Totally Implantable Cochlear Implant in Severely to Profoundly Deaf Adults.
Status: COMPLETED
Conditions: Sensorineural Hearing Loss, Bilateral|Cochlear Implants
Interventions: DEVICE: Mi2000 Totally Implantable Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness of Experiential Fibrowalk Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Experiential FW|BEHAVIORAL: Traditional FW|BEHAVIORAL: Online FW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Attention Training on Symptoms and Emotion Regulation in Depressive Patients
Status: ENROLLING_BY_INVITATION
Conditions: Depression
Interventions: BEHAVIORAL: OCAT-sham|BEHAVIORAL: OCAT|OTHER: Psycho-education video|OTHER: Motivational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunohistochemical Study of Human Teeth Pulp Capped With Mineral Trioxide Aggregate (MTA) and Novel Endodontic Cement (NEC)
Status: TERMINATED
Conditions: Direct Pulp Capping
Interventions: OTHER: direct pulp capping and covering the exposed pulp|OTHER: direct pulp capping and covering the exposed pulp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ritmonutra in Subjects Affected by Supraventricular Ectopic Beats Without Structural Heart Disease
Status: TERMINATED
Conditions: Arrhythmia
Interventions: DIETARY_SUPPLEMENT: ritmonutra|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Progressive Aphasia
Interventions: DEVICE: Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS)|DEVICE: Remotely supervised sham tDCS (RS-sham-tDCS)|BEHAVIORAL: Lexical Retrieval Training (LRT)|BEHAVIORAL: Video Implemented Script Training in Aphasia (VISTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity AND Safety Study of the 11 Valent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha)
Status: COMPLETED
Conditions: HPV Infection|HPV-Related Cervical Carcinoma
Interventions: BIOLOGICAL: Biological/Vaccine: 11-valent recombinant human papilloma virus vaccine (Hansenula polymorpha)|BIOLOGICAL: 9-valent HPV vaccine（Gardasil 9）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South America
Status: COMPLETED
Conditions: Dengue|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: Live, attenuated, recombinant dengue serotype 1 , 2, 3 , and 4 virus|BIOLOGICAL: NaCl 0.9%|BIOLOGICAL: Tetanus toxoid, reduced diphtheria toxoid, acellular pertussis vaccine adsorbed|BIOLOGICAL: Meningococcal A+C vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Collection of SPOT EGMs And inTra-Cardiac Impedance for Atrio-ventricUlar and inteR-ventricular Delays optimizatioN
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DEVICE: Signals collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabeculectomy
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DRUG: TGF-β2 antisense oligonucleotide|PROCEDURE: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation and Dynamic Balance in Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Portable Neuromodulation Stimulation|DEVICE: Sham|OTHER: Gait and balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of MSCs Derived Pleiotropic Factors on Wound Healing in Endonasal Surgeries
Status: UNKNOWN
Conditions: MSCs Derived Pleiotropic Factors on Wound Healing in Endonasal Surgeries
Interventions: BIOLOGICAL: MSCs Derived Pleiotropic Factors|OTHER: physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial on Robotic Assisted Resection for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Adenocarcinoma
Interventions: PROCEDURE: robotic assisted rectal resection|PROCEDURE: laparoscopic rectal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain
Status: NOT_YET_RECRUITING
Conditions: Phantom Limb Pain|Pain, Chronic
Interventions: DRUG: Epidural catheter|DRUG: Continuous sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Study of Individualized Care Plans for Hematopoietic Cell Transplant Survivors
Status: COMPLETED
Conditions: Adult Hematopoietic Cell Transplant (HCT) Survivors 1-2 Yrs Post Most Recent HCT
Interventions: OTHER: Individualized Survivorship Care Plan (SCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Pharmacokinetics (PK), Safety, Tolerability of SR750 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SR750 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery
Status: RECRUITING
Conditions: Cyanotic Heart Disease|Cardiopulmonary Bypass
Interventions: DRUG: Methylprednisolone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Thrombotic Disease
Interventions: DRUG: DS-1040b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)Treatment
Status: TERMINATED
Conditions: Diabetic Proliferative Retinopathy|Vascular Vein Oclussion|Choroidal Neovascularization
Interventions: DRUG: Intravitreal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Protein Before Night Sleep to Improve Recovery and Performance in Runners
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Sport beverages Protein|DIETARY_SUPPLEMENT: Sport beverages Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Saphenous Nerve Blockade for Outpatient Knee Anterior Cruciate Ligament Surgery
Status: UNKNOWN
Conditions: Postoperative Analgesia for Anterior Cruciate Ligament Surgery of the Knee
Interventions: PROCEDURE: Saphenous nerve blockade|PROCEDURE: Femoral nerve blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Large Scale Implementation of Community Based Mental Health Care for People With Severe and Enduring Mental Ill Health in Europe
Status: UNKNOWN
Conditions: Mental Disorders, Severe
Interventions: OTHER: Mobile team community mental health services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Trial of Docetaxel and Oxaliplatin in Patients With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: docetaxel, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copanlisib and Gemcitabine in Relapsed/Refractory PTCL
Status: COMPLETED
Conditions: Mature T-Cell and NK-Cell Neoplasm
Interventions: DRUG: Copanlisib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nimodipine for Treating Acute Massive Cerebral Infarction
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Nimodipine|DRUG: Saline + citicoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg|DRUG: Lopressor HCT® Tablets 100/50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evidence-Based Robot-Assistant in Neurorehabilitation
Status: RECRUITING
Conditions: Stroke|Paresis|Neglect, Hemispatial
Interventions: DEVICE: E-BRAiN therapy|BEHAVIORAL: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sym004 in Combination With Nivolumab Versus Nivolumab Monotherapy in EGFR-amplified Squamous Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Sym004|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Procedure-Specific Approach To Minimize Fistulaization of The Perianal Abscess Cavity After Surgical Drainage
Status: RECRUITING
Conditions: Perianal Fistula
Interventions: PROCEDURE: Non Packing of perianal abscess cavity after drainage|PROCEDURE: Packing of perianal abscess cavity after drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Preconditioning and Acute Kidney Injury in HTX
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Status: COMPLETED
Conditions: Carcinoma, Transitional Cell|Urinary Bladder Neoplasms|Urologic Neoplasms|Renal Pelvis Neoplasms|Urothelial Cancer|Ureteral Neoplasms|Urethral Neoplasms
Interventions: DRUG: Enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Peripheral, Cobalt-chromium Sirolimus Eluting Stent (PERS) Versus Cobalt-chromium Stent (Neptune C)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: PERS stent|DEVICE: NEPTUN C stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Piperacillin-tazobactam Versus Piperacillin-tazobactam Plus Glycopeptide in Neutropenic Patients
Status: COMPLETED
Conditions: Hematological Malignancy|Leukemia|Myelodysplasia|Lymphoma|Myeloma|Stem Cell Transplantation
Interventions: DRUG: piperacillin-tazobactam|DRUG: glycopeptide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study of ASONEP™ to Treat Unresectable and Refractory Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: ASONEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-Implant Soft Tissue Integration in Humans: Influence of Material
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: OTHER: Mucointegration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T
Status: UNKNOWN
Conditions: De Novo Akute Myeloid Leukemia (AML)|Secondary Acute Myeloid Leukemia (AML)|Refractory Anemia With Excess of Blasts in Transformation
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Etoposide|DRUG: Fludarabine|DRUG: G-CSF|DRUG: Daunorubicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD
Status: RECRUITING
Conditions: Type2 Diabetes Mellitus|Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Henagliflozein and Metformin|DRUG: Linagliptin and Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of S-1 in Combination With Cisplatin as 1st Line Therapy in Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability in Patients With Metastatic Breast Cancer Receiving Treatment With Caelyx (Study P04878)(COMPLETED)
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Pegylated Liposomal Doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness of AKYNZEO® and Standard of Care (Including EMEND®) for the Prevention of Nausea and Vomiting (CINV) in Cancer Patients
Status: UNKNOWN
Conditions: Oncology
Interventions: DRUG: Akynzeo|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pericardic Adipose Pedicle Transposition Over the Myocardial Infarct (adiFLAP Trial)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Pericardial adipose pedicle (adiFLAP) transposition.|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects.
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Pegcetacoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Drug-Drug Interaction Between Itraconazole or Gemfibrozil and JNJ-56021927
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-56021927|DRUG: Itraconazole|DRUG: Gemfibrozil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplements for the Treatment of Angelman Syndrome
Status: COMPLETED
Conditions: Angelman Syndrome|Nervous System Diseases
Interventions: DRUG: Betaine|DRUG: Creatine|DRUG: Metafolin|DRUG: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT