pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial to Assess the Safety, Tolerability and Immunogenicity of MenABCWY in Healthy Infants
Status: TERMINATED
Conditions: Meningococcal Vaccine
Interventions: BIOLOGICAL: MenABCWY|BIOLOGICAL: Bivalent rLP2086 (60-µg Dose)|BIOLOGICAL: Bivalent rLP2086 (120-µg Dose)|BIOLOGICAL: Bexsero|DRUG: Prophylactic Liquid Paracetamol (PLP)|BIOLOGICAL: Nimenrix|OTHER: Placebo|DRUG: Scheduled Liquid Paracetamol (SLP)|DRUG: Therapeutic Liquid Paracetamol (TLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: R-(-)-Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage IV Prostate Cancer
Interventions: DRUG: AT-101|DRUG: Bicalutamide|OTHER: LHRH agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC), Chemo-Naive, Who Received a Prior Diethylstilbestrol Therapy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Androgen deprivation therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Local Wound Infiltration After Modified Radical Mastectomy
Status: RECRUITING
Conditions: Post Operative Pain|Erector Spinae Plane Block|Local Infiltration
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: local wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy
Status: RECRUITING
Conditions: Bradycardia|Heart Failure|Pacemaker-Induced Cardiomyopathy|Conduction Block, Atrioventricular|Cardiac Remodeling, Ventricular
Interventions: DEVICE: Left bundle branch area pacing (LBBAP)|DEVICE: Right ventricular pacing (RVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Monarda Didyma Extract Supplementation on Biological Ageing
Status: COMPLETED
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Monarda Didyma extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A PK Study Comparing VeraCept vs. ParaGard Intrauterine Devices (IUDs)
Status: ACTIVE_NOT_RECRUITING
Conditions: Women at Risk for Pregnancy
Interventions: DRUG: VeraCept|DRUG: ParaGard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Efficacy of Fixed-dose Combination Sofosbuvir + Ledipasvir, 8 vs. 12 Weeks in Chronic Hepatitis C Genotype 6
Status: COMPLETED
Conditions: PT-NANBH
Interventions: DRUG: 8 weeks SOF/LED|DRUG: 12 weeks SOF/LED
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF HAND AND BACK MASSAGE ON PAIN, SLEEP AND SELF-CARE IN WOMEN UNDERGOING HYSTERECTOMY
Status: ENROLLING_BY_INVITATION
Conditions: Sleep|Pain|Self Efficacy
Interventions: OTHER: hand massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exercise Intolerance in Renal Failure
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Tetrahydrobiopterin|DRUG: Placebo|DIETARY_SUPPLEMENT: Folate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Orally Administered Ibuprofen and Placebo in Delayed Onset Muscle Soreness
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: DRUG: Acetaminophen 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of an Artificial Intelligence System for Intelligent Pathological Diagnosis and Therapeutic Effect Prediction Based on Multimodal Data Fusion of Common Tumors and Major Infectious Diseases in the Respiratory System Using Deep Learning Technology.
Status: RECRUITING
Conditions: Artificial Intelligence|Deep Learning|Pathology, Molecular|Medical Informatics|Database|Lung Cancer|Pulmonary Tuberculosis|Covid19
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brazilian Heart-Prevent Meal - A Pilot Randomized Clinical Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Brazilian heart-prevent meal|OTHER: Heart prevent control meal weekly|OTHER: Heart prevent control Meal monthly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Self-verification and Support Via Mobile Phones Drastically Improves Tuberculosis Treatment Success in LMIC Settings
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BEHAVIORAL: Keheala|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare
Status: COMPLETED
Conditions: Healthy Adults (Full Study and Extension Phase)|Hypertrophic Cardiomyopathy or Dilated Cardiomyopathy
Interventions: OTHER: Family History + Whole Genome Sequencing|OTHER: Family History Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of APD421 as PONV Treatment (Prior Prophylaxis)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: APD421|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Registry for Patients Undergoing AUS Surgery for Female SUI Due to ISD
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence|Urinary Incontinence, Stress|Lower Urinary Tract Symptoms|Urination Disorders|Urologic Diseases
Interventions: OTHER: Questionnaires on Urinary Incontinence-, Sex Function- and Quality of Life (ICIQ-UI-SF, ICIQ-FLUTSsex, ICIQ-LUTSqol, PGI-I)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression
Status: UNKNOWN
Conditions: Radiculopathy|Spondylolisthesis|Lumbar Spinal Stenosis
Interventions: PROCEDURE: Decompression using the iO-Flex® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The National Lipedema Study
Status: RECRUITING
Conditions: Lipedema
Interventions: PROCEDURE: Liposuction early|PROCEDURE: Liposuction late|OTHER: Standard conservative treatment|OTHER: Standard conservative treatment with Intermittent Pneumatic Compression (IPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Multicenter Study Comparing Docetaxel Plus Cisplatin and 5-FU to Cisplatin Plus 5-FU in Advanced Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasm
Interventions: DRUG: XRP6976
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Rehabilitation Program on PAH Patients Treated With Macitentan.
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Probiotics on Amino Acid Absorption
Status: ACTIVE_NOT_RECRUITING
Conditions: Protein Digestion|Gastrointestinal Microbiome
Interventions: DIETARY_SUPPLEMENT: AMILI Probiotic pills|DIETARY_SUPPLEMENT: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study of mRNA Vaccine (ABOR2014/IPM511) in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Neoantigen vaccine, I.M injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Atorvastatin in Children With Chronic Hyperlipidemia Secondary to Nephrotic Syndrome
Status: TERMINATED
Conditions: Nephrotic Syndrome|Hyperlipidemia
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Saline|BIOLOGICAL: Exendin-9,39
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Safety Study of Amifampridine Phosphate in MuSK-MG (Muscle Specific Tyrosine Kinase Myasthenia Gravis)
Status: TERMINATED
Conditions: Myasthenia Gravis, MuSK|AChR Myasthenia Gravis
Interventions: DRUG: Amifampridine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells as First-line Treatment for Patients With Acute Graft Versus Host Disease
Status: RECRUITING
Conditions: aGVHD
Interventions: OTHER: hUC-MSCs|OTHER: glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota
Status: COMPLETED
Conditions: Mechanisms, Defense
Interventions: DIETARY_SUPPLEMENT: GP-SPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: B7-H3 CAR-T for Recurrent or Refractory Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma|Refractory Glioblastoma
Interventions: DRUG: Temozolomide|BIOLOGICAL: B7-H3 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Blood Pressure in Pregnancy Using Mercury and Automated Device
Status: COMPLETED
Conditions: Hypertension|Pregnancy|Pre Eclampsia
Interventions: DEVICE: Automated blood pressure recording device Omron HEM 705CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis|Hepatic Encephalopathy|Ascites|Varices|SBP - Spontaneous Bacterial Peritonitis
Interventions: DRUG: Allopurinol 300 MG|DRUG: Atorvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: tiotropium bromide|DRUG: salmeterol xinafoate|DRUG: beclomethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy Improves Outcome of Hypoxic-Ischemic Encephalopathy
Status: UNKNOWN
Conditions: Hypoxic-ischemic Encephalopathy
Interventions: DEVICE: hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy of Ticagrelor Versus Aspirin on Blood Viscosity in Peripheral Artery Disease Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Peripheral Artery Disease|Type 2 Diabetes
Interventions: DRUG: Aspirin|DRUG: Ticagrelor|DRUG: Aspirin Placebo|DRUG: Ticagrelor Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Motor Cortex Stimulation for Pain Control
Status: COMPLETED
Conditions: Neuropathic Pain|Phantom Limb Pain|Stump Pain|Brachial Plexus Avulsion|Deafferentation Pain|Facial Pain|Complex Regional Pain Syndrome
Interventions: DEVICE: motor cortex stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Crosslinking in Keratoconus and Corneal Ectasia
Status: WITHDRAWN
Conditions: Progressive Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgeon-performed Intraoperative Transoral Ultrasound for Cancer of Unknown Primary
Status: COMPLETED
Conditions: Cancer of Unknown Primary Site|Unknown Primary Cancer|Unknown Primary, Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Transoral Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety Study for JNJ-18054478 in Asthma Patients.
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: JNJ-18054478|DRUG: sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of ESC-derived Dopamine Progenitor Cell Therapy in PD Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: Allogenic embryonic stem cell-derived A9 dopamine progenitor cell (A9-DPC) Low Dose|BIOLOGICAL: Allogenic embryonic stem cell-derived A9 dopamine progenitor cell (A9-DPC) High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectivity and Safety of Irreversible Electroporation for Refractory Neoplasms in Liver and Pancreas
Status: UNKNOWN
Conditions: Refractory Neoplasms
Interventions: PROCEDURE: Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study to Assess the Hepatic Protection Effect of SNP-612, in Patients With NAFLD
Status: TERMINATED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: SNP-612 dose1|DRUG: SNP-612 dose2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment the sExual Quality of Life in Breast Cancer Patients Receiving oncoSexology Supportive Care on Proactive Versus On-request
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Quality of life questionnaire (QLQ)|OTHER: Satisfaction survey|OTHER: Assessment of patient needs in the field of oncosexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid-use Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Doxycycline and Rifampicin on Biomarkers of Alzheimer's Disease in the Cerebrospinal Fluid
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: doxycycline|DRUG: rifampicin|DRUG: Placebo matched to doxycycline|DRUG: Placebo matched to Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
Status: NOT_YET_RECRUITING
Conditions: Opioid Withdrawal|Chronic Pain
Interventions: DRUG: Buprenorphine Patch|DRUG: Placebo|DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Deferoxamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ondansetron Versus Metoclopramide in Treatment of Vomiting in Gastroenteritis
Status: COMPLETED
Conditions: Gastroenteritis
Interventions: DRUG: Treatment 1. Metoclopramide|DRUG: Treatment 2 Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Continuation Study of the AeriSeal® System Administered at 3 to 4 Sites During a Single Treatment Session for Lung Volume Reduction in Patients With Advanced Emphysema
Status: TERMINATED
Conditions: Pulmonary Emphysema|Chronic Obstructive Pulmonary Disease(COPD)|Lung Diseases
Interventions: DEVICE: AeriSeal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for Fibromyalgia Symptoms (INFORM Trial)
Status: RECRUITING
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Motor Function
Interventions: DEVICE: Active Repetitive Transcranial Magnetic Stimulation (rTMS)|DRUG: Fluoxetine|DEVICE: Sham repetitive transcranial magnetic stimulation (rTMS)|DRUG: Placebo Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a New Formulation of Insulin Glargine With Lantus in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: HOE901-U300 (Insulin glargine new formulation)|DRUG: Lantus (Insulin glargine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine and Humidification for Cpap IN Osas Key Treatment (THINK Study)
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive|OSA|Sleep|Sleep Disorder|Hypersomnia
Interventions: DEVICE: Telemedicine & Humidification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose
Status: UNKNOWN
Conditions: Impaired Glucose Tolerance|Insulin Sensitivity|Glucose Metabolism Disorders
Interventions: DRUG: Metformin capsule 500 mg, Empagliflozin encapsulated tablet 10 mg, Pioglitazone encapsulated tablet 30 mg, Linagliptin encapsulated tablet 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves
Status: COMPLETED
Conditions: Chronic Pain|Diabetic Neuropathies|Diabetes Mellitus
Interventions: DRUG: Cebranopadol 100 µg|DRUG: Cebranopadol 300 µg|DRUG: Cebranopadol 600 µg|DRUG: Pregabalin|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Combines With Bevacizumab and PD-1 Inhibitor in Non-squamous NSCLC
Status: RECRUITING
Conditions: PFS|OS
Interventions: DRUG: PD-1 inhibitor, Bevacizumab, Carboplatin, Cisplatin, Pemtrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Zilver Vascular Stent in the Iliac Arteries (ZIPS)
Status: COMPLETED
Conditions: Peripheral Arterial Disease (PAD)
Interventions: DEVICE: Peripheral Vessel Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease
Status: TERMINATED
Conditions: Chronic Graft-versus-Host-Disease|Oral Mucosal Disease Due to Graft-versus-host Disease
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Neoadjuvant Doxorubicin and Cyclophosphamide -> Docetaxel With Lapatinib in Stage II/III Her2Neu+ Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Pegfilgrastim|DRUG: Filgrastim|DRUG: Dexamethasone|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative High-dose Dexamethasone and Emergency Laparotomy
Status: COMPLETED
Conditions: Intestinal Obstruction and Ileus|Perforated Viscus|Sepsis|Pathophysiology|Inflammatory Response
Interventions: DRUG: Dexamethasone 1 mg/kg|DRUG: Physiologic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding the Mechanism(s) of Action on the Modified Atkins Diet for Epilepsy: Human Brain Tissues
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: Modified Atkins Diet (MAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Radiological Outcomes Following Insertion of a Novel Removable Percutaneous Interspinous Process Spacer: an Initial Experience.
Status: COMPLETED
Conditions: Degenerative Lumbar Spinal Stenosis|Neurologic Intermittent Claudication
Interventions: OTHER: percutaneous removable interspinous process
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Th9/IL-9 and Early Enteral Nutrition in Sepsis
Status: UNKNOWN
Conditions: Sepsis|Intestinal Mucosal Barrier|Th9 Cells|Enteral Nutrition
Interventions: OTHER: Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo-controlled Study to Evaluate Safety & Efficacy of Sarecycline in Treatment of Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Sarecycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Mepivacaine|DRUG: Mepivacaine plus Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect on Oro-dental Complications of Intensity Modulated Radiotherapy (IMRT) Versus Conventional Radiotherapy in Patients With Cancer of the Head or Neck
Status: COMPLETED
Conditions: Cancer: Head or Neck
Interventions: PROCEDURE: IMRT versus conventional radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza.
Status: COMPLETED
Conditions: Common Cold
Interventions: DRUG: Test tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DRUG: Lidocaine|DRUG: Triamcinolone + Lidocaine|DRUG: Triamcinolone + Lidocaine|DRUG: Triamcinolone + Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Stepping Training Using External Feedback in Spinal Cord Injury Patients
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Stepping training without feedback|OTHER: Stepping training with feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Study of Rebif ® 44mcg Administered Three Times Per Week by Subcutaneous Injection Compared With no Treatment in the Therapy of Relapsing Multiple Sclerosis After Mitoxantrone
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Interferon beta-1a (Rebif)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Controlled Trial of SCH 619734 for the Treatment of Chemotherapy-Induced Nausea and Vomiting (Study P04351AM2)(COMPLETED)
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: SCH 619734 Dose 1|DRUG: SCH 619734 Dose 2|DRUG: SCH 619734 Dose 3|DRUG: SCH 619734 Dose 4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Sleep Disorders|Autism Spectrum Disorder
Interventions: DRUG: NPC-15 Granules Lower Dose|DRUG: NPC-15 Granules Higher Dose|DRUG: NPC-15 Placebo Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension|Pulmonary Hypertension
Interventions: DRUG: Sitaxsentan|DRUG: Sitaxsentan and Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Itacitinib and Alemtuzumab in Treating Patients With T-Cell Prolymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent T-Cell Prolymphocytic Leukemia|T-Cell Prolymphocytic Leukemia
Interventions: BIOLOGICAL: Alemtuzumab|DRUG: Itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Valortim® (MDX-1303) and Its Selected Formulation Components Percutaneous Use
Status: COMPLETED
Conditions: Allergic Reactions
Interventions: BIOLOGICAL: Valortim and selected Components|DRUG: Valortim and Selected Components
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation Program
Status: UNKNOWN
Conditions: Pancreatic Cancer|Liver Cancer|Bile Duct Cancer|Hepatobiliary Cancer|Surgery
Interventions: OTHER: Exercise|OTHER: Nutrition|BEHAVIORAL: Relaxation techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Effect of Intense-Exercise/Moderate-Calorie, Topiramate-Phentermine and Cognitive Behavioral Therapy on Obesity
Status: WITHDRAWN
Conditions: Obesity|Diabetes Mellitus
Interventions: OTHER: Behavioral and Drug|OTHER: Behavioral|OTHER: Behavioral and Drug|OTHER: Behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Magnetic Stimulation in ALS Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Neuromuscular magnetic stimulation (NMMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tamsulosin on Postoperative Urinary Retention
Status: TERMINATED
Conditions: Urinary Retention
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Levalbuterol HFA and Racemic Albuterol HFA in Pediatrics Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Levalbuterol HFA MDI followed by Racemic albuterol HFA MDI|DRUG: Racemic Albuterol followed by levalbuterol HFA MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection
Status: TERMINATED
Conditions: Liver Disease
Interventions: DRUG: Preoperative Gabexate Mesilate group|DRUG: Intraoperative Gabexate Mesilate group|DRUG: hepatectomy with dextrose water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022)
Status: COMPLETED
Conditions: Melanoma|Solid Tumors
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ice Cream Cone Technique With Immediate Implant Placement in Patients With Labial Plate Dehiscence
Status: UNKNOWN
Conditions: Dental Implant|Guided Bone Regeneration
Interventions: PROCEDURE: Ice cream cone technique with immediate implant as a flapless bone regenerative method in management of patients with labial plte dehiscence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Cerclage With Vaginal Progesterone in Asymptomatic Twin Pregnancies With a Sonographic Short Cervix
Status: UNKNOWN
Conditions: Twin; Pregnancy, Affecting Fetus or Newborn
Interventions: PROCEDURE: Cervical cerclage|DRUG: vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants.
Status: COMPLETED
Conditions: Vaccines, Pneumococcal
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 7-valent Pneumococcal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Double Blinded, Randomized, Parallel Assignment Study to Demonstrate the Efficacy of DA9601
Status: COMPLETED
Conditions: NSAID-associated Gastroduodenal Injury
Interventions: DRUG: Stillen|DRUG: Cytotec (reference drug)|DRUG: NSAID (Aceclofenac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth
Status: RECRUITING
Conditions: Dietary Proteins|Indicator Amino Acid Oxidation
Interventions: DIETARY_SUPPLEMENT: 2% milk beverage|DIETARY_SUPPLEMENT: Almond milk alternative beverage|DIETARY_SUPPLEMENT: Soy milk alternative beverage|DIETARY_SUPPLEMENT: Rice milk alternative beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The SAFE Study: Satisfaction and Adherence to Follow-Up With Colposcopy Exams
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia|Uterine Cervix Cancer
Interventions: BEHAVIORAL: Patient Liaison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Recombinant Human Papillomavirus Nonavalent Vaccine in Preventing Human Papilloma Virus in Younger Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papillomavirus-Related Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Visualization of the Stomach During Fasting and Measurement of Intragastric Volume After Ingestion of Fluid: Feasibility and Application of Three Dimensional Ultrasound in Healthy Subjects
Status: COMPLETED
Conditions: Echocardiography, Three-Dimensional
Interventions: DEVICE: 3D echography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Percutaneous Closure of the Left Atrial on the Maximum Proto-diastolic Speed of the Mitral Ring Measured by Tissue Doppler (ACTIFER)
Status: UNKNOWN
Conditions: Tissue Doppler|Left Atrial Closure
Interventions: PROCEDURE: Trans thoracic echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: rhBMP-2 Versus Vivigen in Lumbar Fusion Procedures
Status: TERMINATED
Conditions: Lumbar Spine Degeneration
Interventions: BIOLOGICAL: 5cc Vivigen and local autograft|BIOLOGICAL: Small kit rhBMP-2 with local autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Everolimus-containing Chemotherapy in HER2- mBC Patients With PI3K/AKT/mTOR Mutations Study
Status: COMPLETED
Conditions: Breast Cancer|PI3K/AKT/mTOR Pathway Mutation|Everolimus
Interventions: OTHER: No intervention, it was a retrospective study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Deep Transcranial Magnetic Stimulation (TMS) for Treatment-resistant Depression and Neuroanatomical Correlates: a Clinical Study Coupled With Positon Emission Tomography (PET)
Status: COMPLETED
Conditions: Pharmacoresistant Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS - ) - MagPro®|DEVICE: Positon Emission Tomography (PET) - Discovery 710®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Lenvatinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: therapeutic surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Palmar Fibromatosis
Interventions: OTHER: Extracorporeal Shock Wave Therapy|OTHER: traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Aficamten in Pediatric Patients (Age 12 to <18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
Status: RECRUITING
Conditions: Pediatric|Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: Aficamten|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Structural Characterization of Hub's Vulnerability in Neurological Diseases Assessed by Ultra High Field Structural and Functional MRI
Status: UNKNOWN
Conditions: Diffuse Diseases
Interventions: DEVICE: MRI 7T|DEVICE: MRI 3 T|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants Ages 4-11 Years Old With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclomethasone dipropionate BAI|DRUG: Placebo BAI|DRUG: albuterol/salbutamol 90 mcg|DRUG: Beclomethasone dipropionate MDI|DRUG: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kinesio-tape and Shock Wave Therapy on Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis|Calcaneus Spur
Interventions: DEVICE: Kinesio tape|DEVICE: Extracorporeal shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers.
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MVA85A (Tuberculosis vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel|DRUG: DUAC® Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC
Status: COMPLETED
Conditions: Intermittent Claudication|Peripheral Vascular Disease
Interventions: DRUG: Niacin Extended Release and Lovastatin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ventilation Modalities and Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke|Sleep Apnea, Obstructive
Interventions: DEVICE: Nasal Continuous Positive Airway Pressure (nCPAP)|DEVICE: High-Flow Nasal Cannula (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MHAA4549A in Healthy Volunteers in an Influenza Challenge Model
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: MHAA549A|DRUG: Placebo|DRUG: oseltamivir [Tamiflu]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder|Mental Disorders
Interventions: OTHER: Therapeutic Horseback Riding|OTHER: Barn Activity|OTHER: Hybrid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bryostatin Treatment of Moderately Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Bryostatin 1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of Orally Administered SM08502 in Subjects With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor, Adult
Interventions: DRUG: SM08502
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heel Warming With Mild and Hot Thermofor Applied Before Heel Lance
Status: COMPLETED
Conditions: Nursing Caries
Interventions: OTHER: Heel warming with mild thermofor group|OTHER: Heel warming with hot thermofor group|OTHER: Ineffective heel warming with thermofor group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Ambulatory Monitoring of Patients After High-risk Acute Coronary Syndrome Using Two Different Systems: Biomonitor-2 and Kardia Mobile
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Syncope|Tachycardia|Arrhythmias, Cardiac|Heart Diseases
Interventions: DEVICE: Biomonitor-2 and Kardia mobile|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Coloplast Titan® IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DEVICE: Inflatable Penile Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tranexamic Acid for Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Hemorrhage
Interventions: DRUG: tranexamic acid|DRUG: serum physiologic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Effectiveness of the PulseRider® Aneurysm Neck Reconstruction Device Used in Conjunction With Endovascular Coil Embolization in the Treatment of Wide-Neck Bifurcation Intracranial Aneurysm
Status: TERMINATED
Conditions: Unruptured Wide-neck Intracranial Aneurysms
Interventions: DEVICE: PulseRider® Aneurysm Neck Reconstruction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT