pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pre-operative Prophylaxis With Vancomycin and Cefazolin in Pediatric Cardiovascular Surgery Patients
Status: COMPLETED
Conditions: Congenital Heart Diseases|Aortic Valve Disorder
Interventions: DRUG: Cefazolin 25 mg/kg body weight and Vancomycin hydrochloride|DRUG: Cefazolin 30 mg/kg body weight
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fibre Grain Herb Trial in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Dietary, Herbal|DIETARY_SUPPLEMENT: Positive Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping
Status: ENROLLING_BY_INVITATION
Conditions: DMD|Duchenne Muscular Dystrophy|Duchenne|Exon 44
Interventions: DRUG: AOC 1044
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Encapsulated Calcium Butyrate Dietary Supplement on Gut Health
Status: COMPLETED
Conditions: Healthy|Gastrointestinal Discomfort
Interventions: DIETARY_SUPPLEMENT: Encapsulated Calcium Butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Clock Genes During Fasting and After Food Intake in Type 2 Diabetics
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: OTHER: No Breakfast (NoB)|OTHER: Yes Breakfast (YesB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Human Stress Response in a Simulated ED Setting
Status: RECRUITING
Conditions: Stress Physiology|Stress Reaction|Substance Use Disorders|Methamphetamine-dependence|Stress, Emotional
Interventions: BEHAVIORAL: Standard social stress task|BEHAVIORAL: Stressful experience in the ED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Deciphering a Novel and Unique Brown Adipose Tissue Depot in Women
Status: NOT_YET_RECRUITING
Conditions: Cardiometabolic Diseases
Interventions: BEHAVIORAL: Thermoneutral condition|BEHAVIORAL: Cold condition|BEHAVIORAL: Aerobic exercise condition|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Trunk Kinesio Taping on Trunk Strength, Trunk Endurance, Balance and Plantar Pressure
Status: RECRUITING
Conditions: Trunk|Strength|Endurance|Plantar Pressure
Interventions: OTHER: Kinesitaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Functional Therapy Compared With Pilates in Elderly Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Cognitive functional therapy via tele rehabilitation|OTHER: Pilates via tele rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis
Status: COMPLETED
Conditions: Pulmonary Atelectasis
Interventions: OTHER: KP group|OTHER: KM group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Percutaneous Neuromouldation of the Saphenous Nerve in Patients With Patellofemoral Pain
Status: NOT_YET_RECRUITING
Conditions: Patellofemoral Pain
Interventions: DIAGNOSTIC_TEST: Ultrasound-guided percutaneous neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Sertraline Versus Venlafaxine XR in the Treatment of Major Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: sertraline|DRUG: venlafaxine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK-5823 in Overweight or Obese Participants Who Are Healthy or Have Type 2 Diabetes Mellitus (MK-5823-002)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-5823|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Trial With an Adjuvanted TB Subunit Vaccine (Ag85B-ESAT-6 + IC31)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Antigen (Ag85B-ESAT-6)|BIOLOGICAL: Antigen (Ag85B-ESAT-6) with adjuvant (IC31)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency (OTC-HOPE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ornithine Transcarbamylase Deficiency|Ornithine Transcarbamylase Deficiency Disease|Ornithine Carbamoyltransferase Deficiency (Disorder)|Urea Cycle Disorders, Inborn
Interventions: GENETIC: ECUR-506
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Early Endotracheal Tube Insertion With GlideScope Use
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: ETT First (GlideScope)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of GW786034 (Pazopanib) In Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA)
Status: TERMINATED
Conditions: Corona Virus Infection
Interventions: DRUG: Colchicine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Acetaminophen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Paclitaxel and Pembrolizumab in Treating Patients With Refractory Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Transitional Cell Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects
Status: COMPLETED
Conditions: Malignant Solid Tumor|Lymphomas
Interventions: DRUG: RRx-001|DRUG: RRx-001|DRUG: RRx-001|DRUG: RRx-001|DRUG: RRx-001|DRUG: RRx-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Chemotherapy With or Without Granulocyte-macrophage Colony-stimulating Factor (GM-CSF) for Metastatic Hormone Refractory Prostate Cancer (HRPC)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Docetaxel and GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of the AtbFinder® Test System for Selection of Antibiotic Therapy in Persons With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Lung Infection Bacterial
Interventions: DEVICE: AtbFinder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Diagnostic Value of microRNAs for Inflammatory Bowel Diseases
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn Disease|Healthy|Non-IBD Colitis
Interventions: DEVICE: qPCR diagnostic KIT of microRNAS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating Safety, Tolerability and Clinical Activity of FHND6091 in Patients With Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: FHND6091
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Efficacy of Berodual® Administered Via the Respimat® Device With That Administered Via the Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Berodual® Respimat ® high dose|DRUG: Berodual® Respimat ® low dose|DRUG: Berodual® MDI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Montelukast on Remodelling Markers in Asthmatic Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Montelukast|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Evaluate the Tolerability of a Topical Antibiotic and Retinoid Used in a Combined Regimen With a BPO Wash
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CTGel/ BPO Wash|DRUG: Soap Free Cleanser and CTGel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Block for Headache After Concussion
Status: TERMINATED
Conditions: Concussion|Headache
Interventions: COMBINATION_PRODUCT: Lidocaine in SphenoCath device|COMBINATION_PRODUCT: Saline Solution in SphenoCath device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Pasireotide|DRUG: octreotide LAR 30mg|DRUG: lanreotide ATG 120mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Lactulose|DRUG: L-ornithine L-aspartate|DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Study of Azilsartan Tablets in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: 20mg Azilsartan Tablets|DRUG: 40mg Azilsartan Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity, Safety, and Immunogenicity of Covid-19 Vaccine Booster
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Inactivated vaccine booster|BIOLOGICAL: mRNA vaccine booster|DRUG: Viral vector vaccine booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Degarelix in Men With Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms (LUTS)
Interventions: DRUG: Placebo|DRUG: Degarelix 10 mg|DRUG: Degarelix 20 mg|DRUG: Degarelix 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low-level Laser Therapy on Functional Treatment of Skeletal Class II Patients
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: OTHER: twin block|OTHER: twin block combined with low level laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Lidocaine on Pain After Lumbar Spinal Fusion
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Intravenous lidocaine injection|DRUG: Intravenous normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Disease|Solid Tumor|Acute Myeloid Leukemia|Myelodysplastic Syndromes|Cancer|Relapsed Hematologic Malignancy
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Several Doses of Viaskin Peanut in Adults and Children With Peanut Allergy
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Viaskin Peanut 50 mcg|BIOLOGICAL: Viaskin Peanut 100 mcg|BIOLOGICAL: Viaskin Peanut 250 mcg|BIOLOGICAL: Viaskin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
Status: TERMINATED
Conditions: Glaucoma|Cataract
Interventions: PROCEDURE: Femtolaser surgery|PROCEDURE: Phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Natural Sounds on Attention Restoration Outdoors
Status: RECRUITING
Conditions: Cognitive Fatigue|Mental Fatigue|Behavioral Performance|Heart Rate Variability|Positive and Negative Affect|Inhibition, Psychological|Working Memory|Perceived Restoration
Interventions: OTHER: Masking Sounds|OTHER: No Masking Sounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED)
Status: COMPLETED
Conditions: Asthma|Airway Inflammation
Interventions: DRUG: mometasone furoate/formoterol 100/10 mcg|DRUG: mometasone furoate/formoterol 200/10 mcg|DRUG: mometasone furoate/formoterol 400/10 mcg|DRUG: MF DPI 200 mcg|DRUG: MF MDI 200 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰb/Ⅱ Clinical Study of Clifutinib Besylate Combined With Chemotherapy in the Treatment of Newly Diagnosed AML
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: Clifutinib Besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of CC-90001 in Subjects With Mild, Moderate, and Severe Hepatic Impairment Compared With Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: CC-90001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: DRUG: In-office dental bleaching|DRUG: Low Level Laser Therapy|DRUG: 5% potassium nitrate / 2% sodium fluoride gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04958242|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Aging of Dorsal Hands
Interventions: DEVICE: Restylane Skinboosters Vital Lidocaine|DEVICE: Restylane Vital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: the Impact of Occupational Therapy : a Multicenter Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Elderly Patient|Cancer|Quality of Life
Interventions: OTHER: MCRO+Occupational therapy|OTHER: MCRO without intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Complement Inhibition: Attacking the Overshooting Inflammation @Fter Subarachnoid Hemorrhage (CIAO@SAH)
Status: NOT_YET_RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: DRUG: C1 Esterase Inhibitor Injection [Cinryze]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IndieTrainer: Enabling Individuals With Cerebral Palsy to Receive Gamified Power Mobility Training in Their Own Manual Wheelchairs
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy|Conditions Similar to Cerebral Palsy
Interventions: OTHER: IndieTrainer system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate The Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
Status: COMPLETED
Conditions: Refractory Partial Seizures
Interventions: DRUG: E2007 (perampanel)|DRUG: E2007 (perampanel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Consisting of Gemcitabine And Topotecan in Treating Patients With Refractory or Recurrent Ovarian or Fallopian Tube Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: gemcitabine hydrochloride|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of Medical Yoga Therapy on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Kundalini yoga|BEHAVIORAL: Self care advice|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Multiple Doses of HM15211 in Obese Subjects With NAFLD
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: HM15211|DRUG: Placebo of HM15211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Upper Abdominal Radiation Therapy (LD-UART) + Gemcitabine in Patients With Advanced, Unresectable Pancreatic Cancer (PC)
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Ovarian Neoplasms
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine and Perioperative Cytokine Levels in Blood and Cerebrospinal Fluid in Cerebral Aneurysm Patients
Status: UNKNOWN
Conditions: Aneurysm, Cerebral
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Status: COMPLETED
Conditions: Postprandial Hyperglycemia|Metabolic Disorder, Glucose
Interventions: OTHER: High fat, low carbohydrate diet|OTHER: Low fat, high carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate Efficacy and Safety of Fingolimod 0.5 mg Orally Once Daily Versus Placebo in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients.
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Interventions: DRUG: Fingolimod|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of 3-weekly Versus 5-weekly Schedule of S-1 Plus Cisplatin in Gastric Cancer: SOS
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: S-1 and cisplatin|DRUG: S-1 and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Jerusalem Artichoke and Fermented Soybean Powder Mixture Supplementation on Glucose Control
Status: COMPLETED
Conditions: Prediabetes|Newly Diagnosed Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: jerusalem artichoke and fermented soybeans powder mixture|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy
Status: UNKNOWN
Conditions: Myotonic Dystrophy|Sudden Cardiac Death
Interventions: PROCEDURE: Electrophysiological study|DEVICE: pacemaker (PM) implant, internal cardiac defibrillator (ICD) implant, loop-recorder implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ProspectiveTrial of Proton Beam Combined With Anti-VEGF Therapy for Exudative Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: 24GyE proton and Anti-VEGF|DRUG: 16GyE and anti-VEGF|DRUG: Sham Irradiation and anti-VEGF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor
Status: COMPLETED
Conditions: Bone Mass|Effects of Vibration
Interventions: OTHER: Whole-body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Esophagectomy Associated Respiratory Complications: Ivor-Lewis Versus Sweet Approaches
Status: UNKNOWN
Conditions: Esophageal Cancer|Postoperative Complications|Diaphragm|Pulmonary Function
Interventions: PROCEDURE: Ivor-Lewis Esophagectomy|PROCEDURE: Sweet Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Protection of Ovarian Function With Goserelin Acetate in Premenopausal Early Breast Cancer Patients With Chemotherapy
Status: WITHDRAWN
Conditions: Breast Cancer|Ovarian Function
Interventions: DRUG: Goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell Cancer
Status: COMPLETED
Conditions: Advanced/ Metastatic Renal Cell Cancer
Interventions: DRUG: TKI258
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Interventions in Type 2 Obese Diabetic Patients in the Community
Status: UNKNOWN
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: MUFA diet|BEHAVIORAL: ADA 2003|BEHAVIORAL: Low Glycemic index (LGI) diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns
Status: COMPLETED
Conditions: Meconium Aspiration Syndrome|Persistent Pulmonary Hypertension of Newborn
Interventions: DRUG: Oral Sildenafil|DRUG: Placebo (distilled water)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lymphedema Treatment for Blunt Facial Trauma
Status: UNKNOWN
Conditions: Post-traumatic Facial Edema
Interventions: OTHER: Complete Decongestive Therapy (CDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Care and Gram-negative Pathogen in Children
Status: COMPLETED
Conditions: Tracheal and Oropharyngeal Colonization by Gram-negative Pathogens
Interventions: OTHER: 0,12% digluconate chlorhexidine|OTHER: toothbrushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Study for Molecular Biomarkers and Spatial Transcriptomics of Stage IVa Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Stage IVA Nasopharyngeal Carcinoma
Interventions: RADIATION: Intensity modulated radiation therapy (IMRT) combined with chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adaptive Family Treatment for Adolescent Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Family-Based Therapy (FBT)|BEHAVIORAL: Family-Based Therapy with Intensive Family-Focused treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics
Status: RECRUITING
Conditions: Renal Colic
Interventions: DRUG: Piroxicam|DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome|Obesity|Infertility, Female
Interventions: DRUG: Liraglutide + Metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Amoxicillin|DRUG: Bismuth Subsalicylate|DRUG: Clarithromycin|DRUG: Metronidazole Hydrochloride|DRUG: Omeprazole|DRUG: Tetracycline Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity
Status: COMPLETED
Conditions: Pediatric obésity
Interventions: BEHAVIORAL: CON|BEHAVIORAL: EX-MEAL|BEHAVIORAL: MEAL-EX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of OPC-262 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: OPC-262 2.5 mg|DRUG: OPC-262 5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of JNJ-39758979 in Symptomatic Adult Patients With Uncontrolled Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: JNJ-39758979 30 mg/d|DRUG: JNJ-39758979 100 mg/d|DRUG: JNJ-39758979 300 mg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injections for Thoracic Outlet Syndrome
Status: UNKNOWN
Conditions: Thoracic Outlet Syndrome
Interventions: DRUG: Botulinum Toxin Type A|OTHER: Normal Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Lenalidomide/Bortezomib/Dexamethasone and Panobinostat in Transplant Eligible New Diagnosed Multiple Myeloma (MM) Patients
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Panobinostat|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone|BEHAVIORAL: Symptom Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Udenafil After Radical Resection for Sigmoid Colon and Rectal Cancer
Status: COMPLETED
Conditions: Erectile Dysfunction|Sigmoid Colon Cancer|Rectal Cancer
Interventions: DRUG: Udenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm
Status: COMPLETED
Conditions: Back Muscle Spasm|Back Pain|Back Strain|Back Spasm Upper|Muscle Spasm|Acute Pain
Interventions: DRUG: Tolperisone Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Pioglitazone and Berberine in Treatment of Non-Alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Life style intervention|DRUG: pioglitazone|DRUG: berberine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections.
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: Ozurdex|DRUG: Ozurdex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Status: WITHDRAWN
Conditions: Allogenic Stem Cell Transplantation
Interventions: DRUG: SAR445419
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voices Of Individuals: Challenges and Experiences Of bvFTD
Status: ENROLLING_BY_INVITATION
Conditions: Frontotemporal Dementia|Frontotemporal Degeneration|Frontotemporal Dementia, Behavioral Variant|FTD
Interventions: OTHER: Telephone Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FamCe-HLP- Family-centered Obesity Management Program in Primary Care Settings
Status: RECRUITING
Conditions: Childhood Obesity|Family|Behavior, Health|Lifestyle, Healthy
Interventions: BEHAVIORAL: Family-Centered Healthy Lifestyle Program (FamCe-HLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fluoride Varnish Containing Xylitol Coated Calcium Phosphate Versus Conventional Fluoride Varnish in Management of Hypersensitivity of Exposed Root Surfaces in Adult Patients
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DRUG: Fluoride varnish with xylitol coated calcium and phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
Status: TERMINATED
Conditions: Delirium|Cognitive Impairment|Cognitive Decline|Cognitive Change|Postoperative Cognitive Dysfunction|Postoperative Delirium
Interventions: PROCEDURE: Protocolized general anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of CDX-3379, a Human Monoclonal Antibody Targeting ERBB3, in Combination With the MEK Inhibitor, Trametinib, in Patients With Advanced Stage NRAS Mutant and BRAF/NRAS Wildtype (WT) Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Trametinib daily Until PD|DRUG: CDX-3379 (ERBB3 antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-technical Skills Training and Checklists Versus Standard Training With Checklists for Prevention of Medical Error
Status: COMPLETED
Conditions: Medical Emergencies
Interventions: OTHER: Non technical skills and checklist training in simulation|OTHER: Checklist training simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study of CPX-351 in Children With Relapsed Leukemia or Lymphoma
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Burkitt Lymphoma|Diffuse Large Cell Lymphoma|Gray Zone Lymphoma|Lymphoblastic Lymphoma|Anaplastic Large Cell Lymphoma|Hodgkin Lymphoma
Interventions: DRUG: CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stress on DNA Integrity and the Effect of Cognitive Behavioral Therapy on Stress and Infertility in Women
Status: COMPLETED
Conditions: Infertility|Stress
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans
Status: ACTIVE_NOT_RECRUITING
Conditions: Behavioral Disorder|Endocrine System Disorder
Interventions: OTHER: Focus Group|BEHAVIORAL: Health Education|OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Interview|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Copanlisib in Association With Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinomas Harboring a PI3KCA Mutation/Amplification and/or a PTEN Loss
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Copanlisib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MITO 35a: Olaparib Maintenance Therapy in Newly Diagnosed BRCA Wild-type Advanced Ovarian, Fallopian Tube and Primitive Peritoneal Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nintedanib(BIBF1120) in Thyroid Cancer
Status: COMPLETED
Conditions: Medullary Thyroid Cancer (MTC)|Differentiated Thyroid Cancer (DTC)
Interventions: DRUG: Nintedanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MiHA-loaded PD-L-silenced DC Vaccination After Allogeneic SCT
Status: COMPLETED
Conditions: Hematological Malignancies
Interventions: BIOLOGICAL: MiHA-loaded PD-L-silenced DC Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OpiCapone Effect on Motor Fluctuations and pAiN
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Opicapone 50 mg|OTHER: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy During and After Lumpectomy in Treating Women With Stage I or Stage II Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: intraoperative radiation therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Asthma And Genetics In Patients To Be Treated With Fluticasone Propionate/Salmeterol Or Salmeterol Xinafoate
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate/salmeterol|DRUG: salmeterol xinafoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of CT1812 Treatment on Brain Synaptic Density
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Active Treatment- CT1812 100 mg|DRUG: Active Treatment- CT1812 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orbital Artery Doppler Ultrasound in Brain Death
Status: COMPLETED
Conditions: Brain Death
Interventions: DIAGNOSTIC_TEST: Orbital Doppler ultrasonography|DIAGNOSTIC_TEST: Transcranial Doppler ultrasonography|DIAGNOSTIC_TEST: Computed Tomography Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Promoting Early Detection of Breast Cancer in Rural Rwanda: Impact of Community Health Worker and Nurse Training
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Experimental: Training, Phase 1|OTHER: Experimental: Training, Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC)
Status: COMPLETED
Conditions: Bacteriaemia|Catheter Related Bloodstream Infection
Interventions: DEVICE: central venous catheter|DEVICE: central venous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PreView: The Preventive Video Education in Waiting Rooms Program
Status: COMPLETED
Conditions: Health Status Unknown
Interventions: OTHER: Computer-Assisted Intervention|OTHER: Computer-Assisted Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Pilot and Feasibility Study of a Dietary Intervention With Low-protein Meals in Cancer Patients Receiving Immunotherapies
Status: RECRUITING
Conditions: Medical Oncology|Integrative Oncology|Medical Nutrition Therapy
Interventions: OTHER: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and PK/PD of QGE031 vs. Placebo in Patients With Active Bullous Pemphigoid Despite Oral Steroid Treatment
Status: TERMINATED
Conditions: Bullous Pemphigoid
Interventions: DRUG: QGE031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acceptance and Commitment Therapy for the Management of Quality of Life in Patients Post Myocardial Infarction
Status: RECRUITING
Conditions: Psychological Distress|Type D Personality|Medication Adherence|Quality of Life
Interventions: OTHER: Acceptance and commitment therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Arm Clinical Study of Dendritic Cell Vaccine Loaded With Circular RNA Encoding Cryptic Peptide for Patients With HER2-negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms
Interventions: BIOLOGICAL: CircFam53B-219aa DC vaccine|DRUG: camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of Medical Abortion Using Mifepristone and Buccal Misoprostol
Status: COMPLETED
Conditions: Abortion, First Trimester
Interventions: DRUG: mifepristone-misoprostol treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular I-PRF Injections in Patients With Temporomandibular Joint Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Pain
Interventions: PROCEDURE: I-PRF injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing SOM230 Subcutaneously and Sandostatin Subcutaneously in Acromegalic Patients
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Pasireotide (SOM230), Octreotide (Sandostatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kukui Ahi Navigator Cancer Screening and Treatment Demonstration Project
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer|Prostate Cancer|Colorectal Cancer|Lung Cancer
Interventions: OTHER: Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: GP2013 in the Treatment of RA Patients Refractory to or Intolerant of Standard Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: GP2013|BIOLOGICAL: MabThera|BIOLOGICAL: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IA1 With LVSI, IA2)
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: OTHER: Total Laparoscopic or Robotic Radical Hysterectomy|OTHER: Total Abdominal Radical Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT