pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial of Danhong Injection in Treating Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Danhong Injection|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Metformin Intolerant Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metformin Adverse Reaction
Interventions: DIETARY_SUPPLEMENT: Sanprobi Barrier-multispecies probiotic|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Military Preventive Policy for reCruit Training on COVID-19 Seroconversion
Status: UNKNOWN
Conditions: SARS-CoV Infection|Vitamin D Deficiency|Covid19|Acute Respiratory Tract Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Apixaban for Routine Management of Upper Extremity Deep Venous Thrombosis
Status: TERMINATED
Conditions: Deep Venous Thrombosis|Upper Extremity Deep Venous Thrombosis|Thrombus|Venous Thromboembolism|Deep Vein Thrombosis
Interventions: DRUG: apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial on the Use of Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow up 18F-AV-1451 Scan in Confirmatory Cohort Subjects From Study 18F-AV-1451-A05
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Flortaucipir F18|PROCEDURE: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of a Community-based Multi-modal Tai Chi Rehabilitation Program for Patients After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: OTHER: 12-week community-based multi-model Tai Chi rehabilitation program|OTHER: Usual post-operative care|OTHER: Untreated asymptomatic controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients
Status: TERMINATED
Conditions: Tenosynovial Giant Cell Tumor|Pigmented Villonodular Synovitis|TGCT|PVNS - Pigmented Villonodular Synovitis
Interventions: BIOLOGICAL: AMB-05X
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tau Tracer Comparison in Healthy Controls and Alzheimer's Disease Patients
Status: WITHDRAWN
Conditions: Healthy|Alzheimer Disease
Interventions: DIAGNOSTIC_TEST: [F18]RO-948|DIAGNOSTIC_TEST: [F18]MK-6240|DIAGNOSTIC_TEST: [F18]AV1451
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Liraglutide and Heart Failure in Type 2 Diabetes
Status: COMPLETED
Conditions: Congestive Heart Failure|Type 2 Diabetes Mellitus
Interventions: DRUG: liraglutide|DRUG: glimepiride|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Exercise-Based Counseling Program Compared With a Standard Counseling Program in Patients With Early-Stage Prostate Cancer
Status: COMPLETED
Conditions: Malnutrition|Prostate Cancer
Interventions: PROCEDURE: nutritional support|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: OTHER
Clinical trial: Bovine Colostrum in Prevention of Sepsis and Retinopathy of Prematurity
Status: COMPLETED
Conditions: Preterm
Interventions: DIETARY_SUPPLEMENT: The bovine colostrum ( trade name : baby steps sachets, 300mg )|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Vectical in Combination With Clobex Spray to Treatment Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Calcitriol ointment|DRUG: Clobetasol spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure (BETA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CardioPumlonary Management System (CPM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early-Onset Colorectal Cancer Recurrence
Status: COMPLETED
Conditions: Colorectal Cancer Recurrent|Colorectal Cancer|Colorectal Neoplasms|Colorectal Adenocarcinoma|Colorectal Cancer Stage I|Colorectal Cancer Stage II|Colorectal Cancer Stage III
Interventions: OTHER: ENCORE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery
Status: COMPLETED
Conditions: Hemorrhoids|Anal Fistula
Interventions: DEVICE: Gelfoam|OTHER: Bosmin gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Wireless CranioFacial Nerve Stimulation (CFNS) for the Treatment of CranioFacial Neuropathic Pain
Status: COMPLETED
Conditions: Facial Pain
Interventions: DEVICE: Halo Craniofacial Nerve Stimulator System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Delayed Cord Clamping on Haematological Status in Low Birth Weight Infants
Status: COMPLETED
Conditions: Low Birth Weight|Perinatology|Iron Status|Cord Clamping
Interventions: PROCEDURE: Cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pivotal Bioequivalence Study of Exemestane 25 mg Tablets Under Fasting Conditions in Healthy Subjects
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Reference product (A) Aromasin (Exemestane)|DRUG: Test product (B) Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Synergistic Effects of PD-1 Antibody and Chemotherapy Followed by Surgery in Limited-metastatic G/GEJ Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer
Interventions: PROCEDURE: Radical surgery|DRUG: PD-1 Monoclonal Antibody|DRUG: XELOX Chemotherapy Regimen|PROCEDURE: Local Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Evaluation of the Efficiency of a Device for the Diagnosis of an Internal Rectal Prolapse, a Pelvic Floor Ptosis and for the Determination of an Internal Hernia Into the Douglas Pouch
Status: UNKNOWN
Conditions: Internal Rectal Prolapse|Pelvic Floor Ptosis|Internal Hernia Into the Douglas Pouch
Interventions: DEVICE: Colorectal Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Examining the Efficacy of Escitalopram Oxalate Upon Depressive Symptoms and Fatigue in HIV Seropositive Women
Status: TERMINATED
Conditions: Depression|HIV
Interventions: DRUG: Placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Temozolomide in Treating Patients With Metastatic Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Inflammation and Fibrosis Index, Combining MRI and PET 18F-FDG, in Patient's With Crohn's Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DIAGNOSTIC_TEST: abdominal [18F]FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Determination of the Efficacy of Slendertone® Face to Tone the Muscles of the Face and Reduce the Signs of Facial Aging
Status: COMPLETED
Conditions: Facial Muscle Toning
Interventions: DEVICE: Slendertone Face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor
Status: TERMINATED
Conditions: Leukemia, Myeloid, Chronic|Anemia, Aplastic|Myelofibrosis|Lymphoma|Hodgkin Disease|Leukemia, Lymphocytic, Chronic|Leukemia, Myelocytic, Acute|Leukemia, Lymphocytic, Acute
Interventions: DRUG: Parathyroid Hormone (teriparatide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Interchangeability of Infanrix™ IPV/Hib and Pediacel® at 2,4 & 6 Months of Age
Status: COMPLETED
Conditions: Infant Immunizations
Interventions: BIOLOGICAL: Pediacel® and Infanrix™-IPV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: travoprost 0.004% and brinzolamide 1%|DRUG: fixed combination of timolol 0.5% and dorzolamide 2% plus travoprost vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Blood Sparing Strategies: Single Shot High Dose Erythropoietin Two Days Before Heart Surgery
Status: COMPLETED
Conditions: Blood Transfusion
Interventions: DRUG: Erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Status: COMPLETED
Conditions: Diabetes|Prediabetes|Dysglycemia|Overweight|Obesity|Dyslipidemia|Hypertension|Metabolic Syndrome|Cardiovascular Diseases
Interventions: OTHER: Tree nuts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors
Status: RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma|Recurrent CNS Tumor, Adult|Recurrent, CNS Tumor, Childhood|Refractory Primary Malignant Central Nervous System Neoplasm
Interventions: BIOLOGICAL: SC-CAR4BRAIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Bladder Urothelial Carcinoma|Locally Advanced Renal Pelvis Urothelial Carcinoma|Locally Advanced Ureter Urothelial Carcinoma|Locally Advanced Urethral Urothelial Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Recurrent Bladder Urothelial Carcinoma|Recurrent Renal Pelvis Urothelial Carcinoma|Recurrent Ureter Urothelial Carcinoma|Recurrent Urethral Urothelial Carcinoma|Stage III Bladder Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Unresectable Bladder Urothelial Carcinoma|Unresectable Renal Pelvis Urothelial Carcinoma|Unresectable Ureter Urothelial Carcinoma|Unresectable Urethral Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography with Contrast|DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)
Status: COMPLETED
Conditions: Leiomyosarcoma|Liposarcoma|Osteosarcoma|Sarcoma, Soft Tissue|Metastases
Interventions: DRUG: ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Versus LED Phototherapy and Their Effect on Lymphocytes Subsets of Full Term Neonates With Hyperbilirubinemia
Status: COMPLETED
Conditions: Neonatal Hyperbilirubinemia|Phototherapy Complication
Interventions: DEVICE: phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplant|Liver Transplantation
Interventions: BIOLOGICAL: Immunosuppression withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of GABA Modulator AZD7325 on Cutaneous Sensation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 20 mg AZD7325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Periodontal Initial Treatment Combined With Glucocorticoid Therapy for Erosive Oral Lichen Planus
Status: NOT_YET_RECRUITING
Conditions: Oral Lichen Planus|Periodontal Diseases
Interventions: OTHER: Periodontal initial treatment under local anesthesia|DRUG: Glucocorticoid Therapy|BEHAVIORAL: oral hygiene instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of TAP (Transversus Abdominis Plane) and Ilioinguinal/Iliohypogastric Nerve Block for Analgesia of Open Inguinal Herniorrhaphy
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: Preoperative Ultrasound Guided Ilioinguinal/Iliohypogastric Block|PROCEDURE: Preoperative Ultrasound Guided Posterior TAP Block|DRUG: Patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unipolar vs. Bipolar Hemostasis in Total Knee Arthroplasty: A Prospective Randomized Trial
Status: COMPLETED
Conditions: Knee Arthroplasty
Interventions: DEVICE: Aquamantys Device|OTHER: Standard of care treatment for hemostasis during a total knee arthroplasty.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs
Status: TERMINATED
Conditions: For Donors|Related Donors Giving Peripheral Blood Stem Cells (PBSC) to a Sibling|For Recipients|Acute Myelogenous Leukemia (AML)|Acute Lymphoblastic Leukemia (ALL)|Myelodysplastic Syndrome (MDS)|Chronic Myelogenous Leukemia (CML)|Non-Hodgkins Lymphoma (NHL)|Hodgkins Disease (HD)|Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: CDX-301|DRUG: CDX-301 and plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture on Chronic Pelvic Pain in Women With Endometriosis or Adenomyosis
Status: UNKNOWN
Conditions: Endometriosis|Adenomyosis|Pelvic Pain
Interventions: PROCEDURE: acupuncture treatment|PROCEDURE: Sham acupunture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of OPC-12759 Ophthalmic Suspension
Status: COMPLETED
Conditions: Keratoconjunctival Epithelial Disorder
Interventions: DRUG: OPC-12759 ophthalmic suspension|DRUG: Sodium hyaluronate ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Two-Layer Method Preservation and Resuscitation of the Cadaveric Pancreas Before Transplantation
Status: TERMINATED
Conditions: Graft Pancreatitis
Interventions: DRUG: Two-Layer Method pancreas preservation system drug|DEVICE: Two-Layer Method pancreas preservation system device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Ivabradine and Beta-blockers Combination Versus Beta-blockers Up-titration on Right Ventricular Pacing
Status: WITHDRAWN
Conditions: Heart Rate Control in ICD Patients With Heart Failure
Interventions: DRUG: Ivabradine plus beta-blocker (bisoprolol)|DRUG: betablocker titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Health Management for Chronic Obstructive Pulmonary Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Disease|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: The essential public health service（EPHS）for COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Leber's Hereditary Optic Neuropathy
Interventions: DRUG: injection of scAAV2-P1ND4v2 1.18x10e9 vg (Low),|DRUG: injection of scAAV2-P1ND4v2 5.81 X10e9 vg (Med)|DRUG: injection of scAAV2-P1ND4v2 2.4 X10e10vg (High)|DRUG: injection of scAAV2-P1ND4v2 1.0 X10e11vg (Higher)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP)
Status: UNKNOWN
Conditions: Recurrent Respiratory Papillomatosis|Human Papilloma Virus
Interventions: PROCEDURE: Microdebrider|PROCEDURE: Cold-steel surgery (forceps)|PROCEDURE: Carbon dioxide laser|PROCEDURE: Potassium titanyl phosphate (KTP) laser|PROCEDURE: Pulsed dye laser|PROCEDURE: Radiofrequency ablation|PROCEDURE: Monopolar suction diathermy|PROCEDURE: Plasma coagulation|PROCEDURE: Other|OTHER: Adjuvant therapies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Safety and Efficacy Study of AT-101 in Combination With Rituximab in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: AT-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health-connected Devices and Physical Activity Recovery in Bariatric Surgery Patients
Status: COMPLETED
Conditions: Obesity, Morbid|Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Mobility coaching|BEHAVIORAL: Diet coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair
Status: UNKNOWN
Conditions: Brow Ptosis|Facial Scarring
Interventions: DRUG: 5-Fluorouracil|DRUG: Normal Saline Flush, 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Xiang-Sha-Liu-Jun-Zi-Tang in Patients With Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Xiang-Sha-Liu-Jun-Zi-Tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib Combined With Letrozole in Neoadjuvant Treatment of Stage Ⅱ-Ⅲ HR-positive/HER2-negative Breast Cancer
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Dalpiciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaria Challenge in Healthy Volunteers
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: P. falciparum infection|DRUG: Chloroquine|DRUG: Primaquine|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery
Status: NOT_YET_RECRUITING
Conditions: Emergence Delirium
Interventions: OTHER: Binaural beats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Iron|DIETARY_SUPPLEMENT: Multiple micronutrients supplement|DIETARY_SUPPLEMENT: micronutrient fortified porridge powder|DIETARY_SUPPLEMENT: Iron and ascorbic acid fortified water|DIETARY_SUPPLEMENT: Iron plus folic acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lactated Ringer's Solution and PlasmaLyte-A as a Base Solution for Del Nido Cardioplegia
Status: COMPLETED
Conditions: Myocardial Injury
Interventions: DRUG: Lactated Ringer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Types of Ports in Patients With Cancer Receiving Intravenous Chemotherapy
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Vascular Access Device Complications
Interventions: PROCEDURE: vascular access device placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavioral Activation and HIV Risk Reduction for Men Who Have Sex With Men With Crystal Meth Abuse
Status: UNKNOWN
Conditions: Crystal Methamphetamine Abuse|Crystal Methamphetamine Dependence
Interventions: BEHAVIORAL: Behavioral Activation Therapy and Risk Reduction Counseling (BAT-RR)|BEHAVIORAL: Information, Motivation, Behavioral skills change approach to sexual risk reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DEXRAR: DEXamethasone in Revision ARthroplasty
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Dexamethasone|DRUG: Saline isotonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Metabolic Effects of Pre-meal Consumption of Whey in Women at Risk of Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia|Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Brexucabtagene Autoleucel (KTE-X19)|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Root Canal Disinfection Via Diode Laser
Status: COMPLETED
Conditions: Root Canal Infection|Pain
Interventions: DEVICE: Diode laser disinfection|DEVICE: Pseudo diode laser disinfection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval
Status: COMPLETED
Conditions: Gout and Hyperuricemia
Interventions: DRUG: repaglinide; midazolam; SHR4640|DRUG: repaglinide; midazolam; SHR4640; SHR4640 placebo|DRUG: repaglinide; midazolam; SHR4640 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of EnXtra on Accuracy & Reaction Time, Perceived Alertness & Digital Fatigue for Video Gamers
Status: COMPLETED
Conditions: Alert Fatigue, Health Personnel
Interventions: OTHER: Experimental: EnXtra 300 mg/ capsule|OTHER: Microcrystalline cellulose (MCC) 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DEVICE: MS Care Platform (icobrain ms and icompanion ms)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pain Phenotypes in Patients With Fibromyalgia Syndrome
Status: RECRUITING
Conditions: Fibromyalgia, Primary|Fibromyalgia|Chronic Pain Syndrome|Pain, Neuropathic|Nociceptive Pain|Central Sensitisation
Interventions: DIAGNOSTIC_TEST: Pain classification method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability Study of Natura-Alpha in the Treatment of Patients With Active Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: placebo capsule|DRUG: 10 mg Natura-alpha capsule and 10 mg placebo capsule|DRUG: 2 x 10 mg Natura-alpha capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Primary Aldosteronism Among Hypertensive Patients With Atrial Arythmia
Status: COMPLETED
Conditions: Primary Aldosteronism|Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Primary Hyperaldosteronism diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Performance of Short Fiber Reinforced Resin Composite Versus Indirect Nanohybrid Resin Composite Onlay Restorations.
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Ever X Posterior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acupressure on Pain, Nausea-Vomiting, and Mental Well-Being in Oncology Patients
Status: NOT_YET_RECRUITING
Conditions: Pain|Nausea With Vomiting Chemotherapy-Induced|Mental Health Wellness 1
Interventions: OTHER: Self-acupressure|OTHER: Acupressure by therapists|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy
Status: COMPLETED
Conditions: Effects of Immunotherapy
Interventions: OTHER: Sublingual immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Probiotic Lactobacillus Coryniformis K8 on COVID-19 Prevention in Healthcare Workers
Status: UNKNOWN
Conditions: Covid-19
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast Cancer
Status: COMPLETED
Conditions: Breast - Female|Male Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional Bilateral rTMS vs. Bilateral Theta Burst Stimulation for Late-Life Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: LFR followed by HFL|DEVICE: cTBS followed by iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Laparoscopic Approach for Rectal Cancer Surgery
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Robotic-assisted rectal cancer resection and Laparoscopic rectal cancer resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Interaction Potential of Clarithromycin XL on Diltiazem Hydrochloride Cream 2% in Healthy Subjects
Status: COMPLETED
Conditions: CLARITHROMYCIN/DILTIAZEM [VA Drug Interaction]
Interventions: DRUG: Clarithromycin XL|DRUG: 2% Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Capsules Relative to That From Co-administration of ABT-335 and Rosuvastatin for the 5/45mg Dosage Form.
Status: COMPLETED
Conditions: Adverse Events|Pharmacokinetic Variables
Interventions: DRUG: ABT-143|DRUG: ABT-335 and rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Thoracic Surgery, Video-Assisted
Interventions: PROCEDURE: ESP with Bupivacaine 0.5%|PROCEDURE: ESP with Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immunotherapy Study of BMS-986301 Alone or in Combination With Nivolumab, and Ipilimumab in Participants With Advanced Solid Cancers
Status: COMPLETED
Conditions: Advanced Solid Cancers
Interventions: DRUG: BMS-986301|BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for "Voices"
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMC125-C211: Trial of TMC125 in HIV-1 Infected Subjects Who Were in a Sponsor Selected TMC125 Trial
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: TMC125
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Recombinant Factor VII as a Prophylactic Therapy for Adolescent Females With Heavy Menstrual Bleeding
Status: COMPLETED
Conditions: Assessing the Bleeding Profile and the Quality of Life of the Enrolled Patients Before and 1 Year After Drug Intervention
Interventions: DRUG: Proph7
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: transcutaneous auricular vagal nerve stimulation|DEVICE: Sham transcutaneous vagal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Paediatric Virtual Autopsy Trial
Status: COMPLETED
Conditions: Stillbirth|Newborn Death|Sudden Infant Death
Interventions: PROCEDURE: Minimally invasive, virtual autopsy|PROCEDURE: Conventional autopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nurse Coaching the Effect of on Glycemic Control, Fear of Hypoglycemia and Risk Perception in Adults With Type 1 Diabetes.
Status: NOT_YET_RECRUITING
Conditions: Nurse's Role|Diabetes Mellitus|Hypoglycemia
Interventions: BEHAVIORAL: nurse coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intervention Programs for Decreasing Caregiver Burden in Caregivers of Patients With Dementia
Status: UNKNOWN
Conditions: Alzheimer's Disease|Dementia
Interventions: BEHAVIORAL: Behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Diffuse Large B-cell Lymphoma|Richter Transformation Lymphoma|Burkitt Lymphoma|Lymphoplasmacytoid Lymphoma|T-cell Non-Hodgkin Lymphoma|Acute Lymphoid Leukemia|Acute Myeloid Leukemia|Waldenstrom Macroglobulinemia
Interventions: DRUG: Zilovertamab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation
Status: NOT_YET_RECRUITING
Conditions: FLT3 Gene Mutation|AML
Interventions: DRUG: Gilteritinib|DRUG: Cytarabine|DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Diagnosis Versus Laser Measurement of Polyps' Size During Colonoscopy and Implications for Surveillance
Status: UNKNOWN
Conditions: Colorectal Polyp
Interventions: DEVICE: AccuMeasure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Elders Preserving Independence in the Community
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Aging
Interventions: BEHAVIORAL: In-home Preventive Health Visits by Advanced Practice Nurse|BEHAVIORAL: On-site Evidence-based Physical Activity, Health and Wellness Classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CoQ10 Biomarker Trial
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Coenzyme Q10|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Anlotinib, Penpulimab and Capecitabine in Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: The combination treatment of anlotinib, penpulimab and capecitabine.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Additive Analgesic Effects of Transversus Abdominis Plane Block in Abdominoplasty Under Spinal Anaesthesia
Status: RECRUITING
Conditions: Abdominoplasty|Spinal Anaesthesia|Transversus Abdominis Plane Block (TAP Block)
Interventions: DRUG: Spinal anaesthesia group (S)|DRUG: Subcostal TAP block and spinal anesthesia group (STAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Transplantation for Osteoarthritis
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Auotologous BMSCs plus autologous PRP|BIOLOGICAL: Auotologous PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aminocaproic Acid (ACA) on Rosacea-specific Inflammation
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Topical aminocaproic acid (ACA) mixed with Vanicream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: First in Human Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1214784
Status: COMPLETED
Conditions: Clinical Trials, Phase I as Topic
Interventions: DRUG: BAY1214784|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Immunomodulatory Formulas on the Number of Postoperative Infections in Head & Neck Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DIETARY_SUPPLEMENT: immunomodulatory supplement|DIETARY_SUPPLEMENT: IMPACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transmaculine One-on-One and Group Empowerment for Targeted HIV Reduction
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|Adherence, Medication
Interventions: BEHAVIORAL: PrEP4T|BEHAVIORAL: LS4TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Comparative Safety and Immunogenicity of Three Lots of Novartis Meningococcal C Conjugate Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: MenC-CRM LIQ|BIOLOGICAL: MenC-CRM ROS|BIOLOGICAL: MenC-CRM EMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Does Cardiac REhabilitation Improve Functional, Independence, Frailty and Emotional outCOmes Following Trans Catheter Aortic ValvE Replacement?
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: OTHER: Cardiac Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RECOVER-AUTONOMIC Platform Protocol
Status: RECRUITING
Conditions: Long COVID|Long Covid19|Long Covid-19
Interventions: DRUG: IVIG + Coordinated Care|DRUG: IVIG Placebo + Coordinated Care|DRUG: Ivabradine + Coordinated Care|DRUG: Ivabradine Placebo + Coordinated Care|DRUG: IVIG + Usual Care|DRUG: IVIG Placebo + Usual Care|DRUG: Ivabradine + Usual Care|DRUG: Ivabradine Placebo + Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccine Attitudes, Intent, and Receipt: Pediatric
Status: COMPLETED
Conditions: Vaccination|Influenza
Interventions: BEHAVIORAL: Local educational information|BEHAVIORAL: National educational information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MOdification of VIsual Outcomes After Optic Neuritis in CIS or MS by Gilenya (MOVING Study)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Verum arm receiving Gilenya®|DRUG: Active Comparator receiving Extavia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transperineal Ultrasound and the Place of Sonopartograph in Travay Follow-up in Term Pregnancy
Status: COMPLETED
Conditions: Intrapartum Transperineal Ultrasound
Interventions: OTHER: transperineal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Creation of Bone Marrow Microenvironment for Treatment of Myelodysplastic Syndrome (MDS) in Conjunction With Allogeneic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Myelofibrosis
Interventions: DEVICE: DBM for creation of bone marrow microenvironment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE)
Status: COMPLETED
Conditions: Effect of Drug|Drug|Toxicity
Interventions: DRUG: Apatinib+IE|DRUG: IE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Onset of Effect in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Symbicort® Compared to Seretide®
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Symbicort Turbuhaler (budesonide/formoterol) 320/9 μg|DRUG: Seretide Diskus (salmeterol/fluticasone) 50/500 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Treatment at the Onset of Necrotizing Enterocolitis (NEC) in Preterm Infants
Status: TERMINATED
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: hydrocortisone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of the Safety and the Efficacy of 2 Antimalarials Depending on HIV Status
Status: TERMINATED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: ARTEMETHER + LUMEFANTRINE VS. SULFADOXINE + PYRIMETHAMINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Menopause Relief EP-40 in Women With Menopausal Symptoms
Status: COMPLETED
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: Menopause Relief EP-40|DIETARY_SUPPLEMENT: Low Dose Black Cohosh|DIETARY_SUPPLEMENT: High Dose Black Cohosh|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial)
Status: UNKNOWN
Conditions: Anesthesia|Cancer
Interventions: DRUG: Lidocaine IV|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3)
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Vemurafenib|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-Therapy Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Opdivo|BIOLOGICAL: Yervoy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT