pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Xcellerated T CellsTM for Non-Hodgkin's Lymphoma (NHL) Patients
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Xcellerated T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deacylated Ghrelin and Beta Cell Function
Status: UNKNOWN
Conditions: the Diabetic Process
Interventions: DRUG: unacylated ghrelin|DRUG: acyl ghrelin|DRUG: combined acyl and desacyl ghrelin|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Effects of a Spread With Added Plant Sterols and Omega-3 Fatty Acids on Blood Lipids
Status: COMPLETED
Conditions: Vascular Diseases|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Margarine enriched with plant sterols and fish oil|DIETARY_SUPPLEMENT: Placebo margarine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Ridaforolimus (MK-8669) in Participants With Solid Tumors (MK-8669-003)(COMPLETED)
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: Ridaforolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium-vitamin D & Periodontal Therapy for Improving Metabolic and Inflammatory Profile Among Pregnant Women
Status: COMPLETED
Conditions: Periodontitis|Inflammation
Interventions: OTHER: Early PT|OTHER: Delayed PT|DIETARY_SUPPLEMENT: Fortified Milk|DIETARY_SUPPLEMENT: Plain Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury
Status: RECRUITING
Conditions: Calcitonin|Neuropathic Pain|Spinal Cord Injury
Interventions: DRUG: Calcitonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Punica granatum Linn.|DRUG: chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebral Monitor Guided Therapy on Cerebral Outcomes After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Cardiac Surgery|Protein Metabolomics|Cerebral Function|Cardiopulmonary Bypass
Interventions: OTHER: Perioperative and postoperative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D and Muscle Strength and Surface (Electromyography) EMG
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Calcium Carbonate|DRUG: cholecalciferol and calcium carbonate|OTHER: lactose placebo|OTHER: lactose granules and tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of NN1250 With Insulin Glargine Plus Insulin Aspart With/Without Metformin and With/Without Pioglitazone in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma
Status: COMPLETED
Conditions: Neovascular Glaucoma
Interventions: PROCEDURE: Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Lag-3 (Relatlinib) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Lomustine|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy
Status: COMPLETED
Conditions: Muscle Spasticity|Cerebral Palsy
Interventions: DEVICE: Swiss DolorClast|PROCEDURE: Traditional conservative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure the Sun Protection Factor (SPF) and Ultraviolet-A Protection Factor (UVAPF) of Four Developmental Sunscreen Formulations
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: OTHER: NGBUV000A, (Expected SPF 30)|OTHER: NGBUV000B, (Expected SPF 30)|OTHER: NGBUV000C, (Expected SPF 30)|OTHER: NGBUV000D, (Expected SPF 30)|OTHER: P3 Standard, (Expected SPF 16)|OTHER: Sunscreen formulation S2|OTHER: Glycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Active Approach to Treat Amblyopia: Perceptual Learning and Video Games
Status: COMPLETED
Conditions: Amblyopia
Interventions: BEHAVIORAL: Perceptual learning|BEHAVIORAL: Video Games|BEHAVIORAL: Occlusion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder|Depression|Anxiety
Interventions: OTHER: Preventive intervention trauma-informed early intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of and Immune Response to Prime/Boost Vaccine Regimens in Healthy, HIV-1 Uninfected, Ad5 Seronegative Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: NYVAC-B|BIOLOGICAL: Placebo|BIOLOGICAL: rAd5|BIOLOGICAL: rAd5|BIOLOGICAL: rAd5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Targeting Investigation and Treatment in Patients With Type 2 Myocardial Infarction
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction Type 2
Interventions: DIAGNOSTIC_TEST: Coronary computed tomography angiography|DIAGNOSTIC_TEST: Invasive coronary angiography|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: Cardiac MRI scan|DRUG: Antiplatelet Drug (Aspirin or Statin)|DRUG: Anticoagulants (Apixaban, Edoxaban, Rivaroxoban, Warfarin)|DRUG: Guideline directed heart failure therapy|DRUG: Statins (Cardiovascular Agents)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity
Status: SUSPENDED
Conditions: Impulsive Behavior
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vorinostat in Treating Patients With Locally Recurrent or Metastatic Cancer of the Urothelium
Status: TERMINATED
Conditions: Localized Transitional Cell Cancer of the Renal Pelvis and Ureter|Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: vorinostat|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MyMenoPlan: Online Resource for Improving Women's Menopause Knowledge and Informed Decision-making
Status: UNKNOWN
Conditions: Menopause|Premenopause|Postmenopause
Interventions: OTHER: MyMenoPlan|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Treatment-Resistant Keratitis
Status: TERMINATED
Conditions: Keratitis
Interventions: BIOLOGICAL: LV-Visio-AMTRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer Pain
Status: COMPLETED
Conditions: Chronic Noncancer Pain
Interventions: DRUG: oxycodone HCl and naltrexone HCl extended-release capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Physical Exercise Performed Through Virtual Reality Games on Chronic Renal Patients During Hemodialysis
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: DEVICE: Group A - Intervention with Virtual Reality (VR)|DEVICE: Group B - Intervention with Stationary Bike (SB)|DEVICE: Group A - Intervention with Stationary Bike (SB) - Crossover|DEVICE: Group B - Intervention with Virtual Reality (VR) - Crossover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Status: COMPLETED
Conditions: Dermatological Non-Disease
Interventions: DEVICE: Princess Filler Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histologic Comparison of Ablative Techniques for Endometriosis
Status: RECRUITING
Conditions: Endometriosis|Endometriosis-related Pain|Endometriosis Pelvic|Endometriosis; Peritoneum
Interventions: DEVICE: Diathermy|DEVICE: CO2 Laser|DEVICE: Argon Beam Coagulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of FloSeal for Prevention of Lymphocele After Lymphadenectomy for Gynecologic Cancer
Status: COMPLETED
Conditions: Gynecologic Cancer|Cervical Cancer|Endometrial Cancer|Ovarian Cancer|Fallopian Tubal Cancer
Interventions: DRUG: FloSeal application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Lifestyle Modification Program on Meaningful Participation and Quality of Life of Independent Taiwanese Older Adults
Status: COMPLETED
Conditions: Quality of Life
Interventions: BEHAVIORAL: Lifestyle modification program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Saliva Stimulation to Immediately Improve Heart Failure Inpatient's Thirst Sensation
Status: COMPLETED
Conditions: Heart Failure|Thirst|Saliva
Interventions: OTHER: lemonade ice cubes|OTHER: water ice cubes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Internet-based Self-help Insomnia Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain
Status: UNKNOWN
Conditions: Acute Sciatica
Interventions: DRUG: Betamethasone OR Dexamethasone Injectable|DRUG: Normal Saline Flush, 0.9% Injectable Solution|DRUG: Dexamethasone Oral Tablet|OTHER: Sham Injection and/or oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Including Synera® in Discussions on Dialysis Access Conversion in Patients With Needle Phobias
Status: TERMINATED
Conditions: Needle Phobia|Phobic Disorders
Interventions: OTHER: Enhanced Needle Phobia Intervention|OTHER: Standard Needle Phobia Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Atrophogenic Potential of Triple Combination Cream for Treatment of Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: Fluocinolone acetonide .1%, hydroquinone 4%, tretinoin .05%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Targeted Focal Laser Thermal Therapy of Prostate Cancer Followed by Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Neoplasm
Interventions: PROCEDURE: Focal Phothtermal Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine Plus Deferoxamine for Patients With Hypotension
Status: COMPLETED
Conditions: Hypotension|Acute Renal Failure
Interventions: DRUG: N-acetylcysteine and deferoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning
Status: RECRUITING
Conditions: Cognitive Decline|Mild Cognitive Impairment|Alzheimer Disease
Interventions: GENETIC: Genetic analysis of APOE and BDNF genes.|DIAGNOSTIC_TEST: EEG recording|DIAGNOSTIC_TEST: CSF collection and AD biomarker measurement|DIAGNOSTIC_TEST: Neuropsychological evaluation|DIAGNOSTIC_TEST: Assessment of cognitive reserve, depression, personality traits and leisure activities|DIAGNOSTIC_TEST: Clinical-neuropsychological follow-up|DIAGNOSTIC_TEST: ERP recording
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tivozanib + Gemcitabine in Metastatic RCC
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Tivozanib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Suturing Material on Scar Healing
Status: COMPLETED
Conditions: Wound Heal|Cesarean Section Complications|Cesarean Wound Disruption|Suture Related Complication
Interventions: OTHER: Monofilament suture|OTHER: Multifilament suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of the Hepatitis B Vaccine Hepavax-Gene TF and a Comparator Hepatitis B Vaccine in Newborns
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HepavaxGene (thiomersal free)|BIOLOGICAL: Engerix B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-Label Study Evaluating Breakthrough Bleeding and Spotting With Norgestimate/Ethinyl Estradiol Tablets Administered as an Extended Regimen
Status: COMPLETED
Conditions: Metrorrhagia
Interventions: DRUG: Norgestimate/Ethinyl Estradiol tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Cytokine Therapy for Hemodialysis InflammatION
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Percutaneous Neuromodulation on the Superior Gluteal Nerve in Patients With Greater Trochanteric Pain Syndrome: A Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Greater Trochanteric Pain Syndrome
Interventions: OTHER: Shockwave Therapy|OTHER: Therapeutic Exercises|OTHER: Ultrasound-Guided Percutaneous Neuromodulation:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cethrin in Acute Cervical Spinal Cord Injury
Status: WITHDRAWN
Conditions: Spinal Cord Injury
Interventions: DRUG: Cethrin (BA-210)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skin Efficacy and Tolerability of a Cosmetic Product Combination Over 3 Months in Subjects With Atopic Eczema
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis|Eczema-Prone Skin
Interventions: OTHER: Body Lotion and Intensive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Music Concert and Inhaler Aromatherapy Applied to Patients Who Have Had Coronary Angiography on Pain Severity, Anxiety and Fear Levels
Status: COMPLETED
Conditions: Anxiety|Pain
Interventions: OTHER: aromatherapy|OTHER: music concert|OTHER: aromatherapy and music concert,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telehealth-Filter Ventilation ( COMET2P1 )
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use
Interventions: OTHER: Ventilated Cigarette Filter|OTHER: Unventilated Cigarette Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Laser Acupuncture Alone or Combined With Pranayama Exercise on Inflammation in Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: OTHER: pranayama plus acupoint stimulation by laser|OTHER: acupoint stimulation by laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: in Vitro Fertilization (IVF) Media Protein and Live Birth Rates
Status: COMPLETED
Conditions: Infertility|Pregnancy Outcome, Live Birth|In Vitro Fertilization
Interventions: OTHER: 10% SSS embryo culture medium protein supplementation|OTHER: 0.5% HSA embryo culture medium protein supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olfactory and Brain Stimulations in Treatment-resistant Depression
Status: RECRUITING
Conditions: Treatment-resistant Depression
Interventions: DEVICE: Non-invasive brain stimulation protocol (intermittent theta burst protocol (iTBS)) combined with pleasant odors delivered during the iTBS procol.|DEVICE: Non-invasive brain stimulation protocol (intermittent theta burst protocol (iTBS)) delivered alone.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Added to Prephase and Consolidation Therapy in Precursor B-acute Lymphoblastic Leukemia in Adults.
Status: ACTIVE_NOT_RECRUITING
Conditions: ALL, Adult
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph 1 Trial of ADI-PEG 20 Plus Cisplatin in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Cutaneous Melanoma, Uveal Melanoma, Ovarian Carcinoma or Other Advanced Solid Tumors
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Dioxide（CO2）Fractional Laser Plus Photodynamic Therapy in Female Patients With Vulvar Lichen Sclerosus
Status: UNKNOWN
Conditions: Vulva Lichen Sclerosus
Interventions: DEVICE: CO2 fractional laser|COMBINATION_PRODUCT: 5-aminolevulinic acid (5-ALA) with red light illumination|DRUG: Mometasone furoate (MMF) 0.1% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tandospirone Combined With Atypical Antipsychotic Drugs in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Risperidone/Olanzapine/Quetiapine/Ziprasidone/Aripiprazole|DRUG: Tandospirone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cardiac Index and Cardiac Output Effect During Maintenance Hemodialysis Between Acetate-Free and Acetate-Based Online Hemodiafiltration
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: BIOLOGICAL: Acetate-free dialysis solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of KADIAN 100 mg When Dosed With Alcohol Under Fasting and Fed Conditions Compared to Water
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: KADIAN Capsule + alcohol (under fasting conditions)|DRUG: KADIAN Capsule + water (under fasting conditions)|DRUG: morphine sulfate IR oral solution + water|DRUG: KADIAN Capsule + alcohol (under fed conditions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma
Status: RECRUITING
Conditions: Upper Tract Urothelial Carcinoma
Interventions: PROCEDURE: RNU|DRUG: Gemcitabine/Cisplatin|DRUG: M-VAC Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Esomeprazole Magnesium DR Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Nexium 40 mg DR Capsules of AstraZeneca LP, USA|DRUG: Torrent's Esomeprazole Magnesium DR Capsules 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Progesterone for Prevention of Preterm Birth After an Episode of Preterm Labor
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Progesterone|DRUG: placebo vaginal capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resolution of Left Atrial-Appendage Thrombus - Effects of Dabigatran in Patients With AF
Status: TERMINATED
Conditions: Atrial Fibrillation or Atrial Flutter|Thrombosis of Left Atrial Appendage
Interventions: DRUG: Dabigatran etexilate|DRUG: Phenprocoumon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensor-controlled Digital Game for Heart Failure Self-management
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Sensor-controlled digital game (SCDG)|BEHAVIORAL: Sensor Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)
Status: TERMINATED
Conditions: Moderate to Severe Primary Dysmenorrhea
Interventions: DRUG: Etonogestrel (ENG) 125 μg + 17β-estradiol (E2) 300 μg vaginal ring|DRUG: Placebo vaginal ring|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Treatment in Total Hip Arthroplasty: A Study to Assess the Effect of Local Analgesia
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ropivacaine, Ketorolac and Adrenalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectıveness of The Sexually Transmıtted Dıseases Educatıon Program for Adolescents
Status: COMPLETED
Conditions: Sexually Transmitted Diseases
Interventions: OTHER: Sexually transmitted diseases training for young adolescents aged 17-21
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Types of Fixation in Arthroscopic Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: single row|PROCEDURE: double row fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial With Metronomic Low-dose Treosulfan, Pioglitazone and Clarithromycin Versus Standard Treatment in NSCLC
Status: UNKNOWN
Conditions: Squamous Cell Lung Cancer|Non-Squamous Cell Lung Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: Pioglitazone|DRUG: nivolumab|DRUG: Treosulfan|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques
Status: COMPLETED
Conditions: Pulmonary Function
Interventions: PROCEDURE: thoracic epidural block|PROCEDURE: paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems
Status: UNKNOWN
Conditions: Arthritis|Asthma|Chronic Obstructive Lung Disease|Diabetes|Heart Failure|Hypertension|Anxiety|Chronic Pain|Depression|Fibromyalgia|Insomnia|Irritable Bowel Syndrome|Problem Drinking|Substance Use Disorder
Interventions: OTHER: Integration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimisation of Nutrition and Medication for Acutely Admitted Older Medical Patients
Status: UNKNOWN
Conditions: Aging|Malnutrition|Drug Prescribing
Interventions: OTHER: Optimisation of nutrition and medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea|Tonsillar Hypertrophy
Interventions: PROCEDURE: Tonsillectomy|PROCEDURE: Tonsillotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Fructose Reduction in Children With Hepatic Steatosis
Status: COMPLETED
Conditions: Non-alcoholic Fatty-liver Disease
Interventions: DIETARY_SUPPLEMENT: Fructose Drink|DIETARY_SUPPLEMENT: Glucose Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Cervical Ripening With Foley Bulb Versus Dilapan-S at Home
Status: WITHDRAWN
Conditions: Induced; Birth|Induction of Labor Affected Fetus / Newborn
Interventions: DEVICE: Foley bulb placement|DEVICE: DILAPAN-S® placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Device Versus Uterine Artery Embolization for Adenomyosis
Status: RECRUITING
Conditions: Adenomyosis
Interventions: PROCEDURE: Intrauterine device|PROCEDURE: Uterine artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Efficacy and Safety of DA-1229 in Patients With CAVD
Status: COMPLETED
Conditions: Calcific Aortic Valve Disease
Interventions: DRUG: DA-1229
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection for AGC
Status: UNKNOWN
Conditions: Gastric Cancer|Gastrectomy|Laparoscopic Surgery|Lymphadenectomy
Interventions: PROCEDURE: laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC114-TiDP3-C182 - A Study to Compare the Oral Bioavailability of a 800 mg Prototype Tablet Formulation of Darunivar (DRV) to That of the 400 mg Commercial Tablet Formulation in the Presence of Low Dose Ritonavir, Under Fasted and Fed Conditions
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: DRV commercial formulation/ DRV new formulation/ rtv 100mg tab|DRUG: DRV commercial formulation/ DRV new formulation/ rtv 100mg tab|DRUG: DRV commercial formulation/ DRV new formulation/ rtv 100mg tab|DRUG: DRV commercial formulation/ DRV new formulation/ rtv 100mg tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile-Based Intervention to Promote Physical Activity Among the Elderly
Status: NOT_YET_RECRUITING
Conditions: Mobile Health|Physical Activity
Interventions: BEHAVIORAL: Mobile Exercise Support|BEHAVIORAL: Self-help physical activity booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
Status: RECRUITING
Conditions: Coagulation Disorder
Interventions: DRUG: TAK-330|DRUG: SOC 4F-PCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuronavigation rTMS to Improve Depressive Episodes of Bipolar Disorder in Adolescent
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DEVICE: Repetitive Transcranial magnetic stimulation|DEVICE: Sham Repetitive Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ba253BINEB Compared to Ba253MDI (Metered Dose Inhaler) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ba253MDI|DRUG: Ba253BINEB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy Volunteers
Status: COMPLETED
Conditions: Sarcoma
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: fluorescence in situ hybridization|GENETIC: microarray analysis|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men
Status: RECRUITING
Conditions: Risk Reduction
Interventions: BEHAVIORAL: Motivational Interviewing Counselling|DEVICE: Point-of-care Urine Tenofovir Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy
Status: RECRUITING
Conditions: Procedural Pain|Pain Catastrophizing|Procedural Anxiety
Interventions: DRUG: Nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intramuscular Oxytocics: A Randomised Control Trial
Status: COMPLETED
Conditions: Post Partum Haemorrhage
Interventions: DRUG: Carbetocin|DRUG: Syntocinon|DRUG: Syntometrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
Status: RECRUITING
Conditions: Stroke|Aphasia
Interventions: DEVICE: Active Comparator: Experimental: Active cathodal tDCS + language training|BEHAVIORAL: Sham Comparator: Placebo cathodal tDCS + Speech and language
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidemiologic Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota
Status: WITHDRAWN
Conditions: Covid19|SARS-CoV Infection|SARS-CoV-2|Corona Virus Infection
Interventions: DIAGNOSTIC_TEST: Specimen Collection|DIAGNOSTIC_TEST: Surveys
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous Insufficiency
Status: UNKNOWN
Conditions: Chronic Venous Insufficiency
Interventions: DIETARY_SUPPLEMENT: Endolex Forte®|DIETARY_SUPPLEMENT: A combination of diosmin and hesperidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of EZN-2968 Weekly in Adult Patients With Advanced Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Carcinoma|Lymphoma
Interventions: DRUG: Intravenous EZN-2968 (anti-HIF-1α LNA AS-ODN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydration, Rehydration, and Blood Viscosity
Status: COMPLETED
Conditions: Dehydration
Interventions: OTHER: Essentia Water|OTHER: Bottled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial for GALNT14 Genotype - Guided, Sorafenib in Combination With TACE in Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sorafenib|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Effect of 10 mg Versus 20 mg Rimonabant in Overweight or Obese Patients
Status: TERMINATED
Conditions: Obesity|Weight Loss
Interventions: DRUG: rimonabant (SR141716)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation
Status: RECRUITING
Conditions: Anxiety
Interventions: DRUG: Midazolam|DRUG: Esketamine|DRUG: midazolam and esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab+Methotrexate(MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of MSPrebiotic on Gut Health in the Elderly
Status: COMPLETED
Conditions: Focus of Study; Impact of MSPrebiotic on Gastrointestinal Microbiota
Interventions: DIETARY_SUPPLEMENT: MSPrebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Combination of Fenofibrate and 40 mg Simvastatin Versus 40 mg Simvastatin Monotherapy
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Fenofibrate/Simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 'Smart Reminder': a Randomized Controlled Trial on the Effect of a Wearable Device
Status: RECRUITING
Conditions: Stroke|Wearable Device
Interventions: DEVICE: Wearable device -'Smart Reminder'|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunoregulation by Controlled Parasite Exposure in Multiple Sclerosis.
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Live Hookworm Larvae|OTHER: Histamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FBS-ASaP: Fibrobronchoscopy in ASpiration Pneumonia in the Emergency Department
Status: RECRUITING
Conditions: Aspiration Pneumonia|Bronchoscopy
Interventions: PROCEDURE: Laryngotracheal Aspiration Procedure Using a Probe in the Emergency Department|PROCEDURE: Aspiration Procedure Using Fibrobronchoscopy in the Emergency Department
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial Overgrowth
Status: COMPLETED
Conditions: Diarrhea Predominant Irritable Bowel Syndrome|Small Intestinal Bacterial Overgrowth
Interventions: OTHER: Serum-derived bovine immunoglobulin protein isolate (SBI)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Omega-3 Fatty Acids Regarding Ergogenic, Anti-inflammatory and Obesity Inhibitory Effects in 8 Year Old Children
Status: COMPLETED
Conditions: Lifestyle-related Condition|Overweight and Obesity|Essential Fatty Acid Deficiency
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Functional Bracing vs Rigid Immobilization After Modified Percutaneous Achilles Tendon Repair
Status: COMPLETED
Conditions: Achilles Tendon Rupture|Percutaneous Repair|Local Anesthesia|Postoperative Complications
Interventions: PROCEDURE: Percutaneous suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: GIP and GLP-1 in Type 1 Diabetes
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: OTHER: GIP|OTHER: GLP-1|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of the FTRD System for Obtaining Full-thickness Intestinal Biopsies
Status: WITHDRAWN
Conditions: Gastrointestinal Motility Disorders
Interventions: PROCEDURE: Endoscopic full-thickness biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Bupivacaine|DRUG: Levobupivacaine|DRUG: Phenylephrine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing the Efficacy of DuoTrav as a Replacement Therapy in Glaucoma Patients in Russia
Status: WITHDRAWN
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004%/Timolol 0.5% Fixed Combination (DuoTrav)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the Active Breathing Control Device to Reduce Radiation Side Effects to Critical Structures in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Active Breathing Coordinator (ABC)|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mesenchymal Cells From Autologous Bone Marrow, Administered Intravenously in Patients Diagnosed With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Bone marrow mesenchymal stem cells autologous|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Intake of Cocoa Flavanols and Arterial Stiffness in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Cocoa flavanols I|OTHER: Control I|OTHER: Cocoa flavanols II|OTHER: Control II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Nature Images Accompanied by Music on Breastfeeding, Breastfeeding Satisfaction and Maternal Attachment"
Status: RECRUITING
Conditions: Breast Feeding
Interventions: OTHER: Natural Landscape Pictures Accompanied by Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOLFOX/FOLFIRI Containing Levofolinic Acid (Zuoyu ®) in the Treatment of Unresectable or Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Unresectable or Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOX/FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy
Status: COMPLETED
Conditions: Post-operative Hemorrhage
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ESDM and PCIT-A in Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Parent-Child-Interaction Therapy adapted for children with autism spectrum disorder (PCIT-A)|BEHAVIORAL: Early Start Denver Model (ESDM) intervention|BEHAVIORAL: 1-hour ESDM|BEHAVIORAL: Early special needs education (ESNE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAA05 Cell Injection in the Treatment of Recurrent / Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: CAR|Acute Myeloid Leukemia
Interventions: DRUG: TAA05 cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
Status: COMPLETED
Conditions: Tooth Loss|Peri-implant Mucosa Defect
Interventions: DRUG: Acellular Dermal Matrix|PROCEDURE: Autologous subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT