pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss
Status: COMPLETED
Conditions: Female Pattern Hair Loss
Interventions: DRUG: Spironolactone|DRUG: Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Three Different Nonpharmacological Methods Used During Vascular Access in Children on Pain and Anxiety
Status: COMPLETED
Conditions: Pain|Anxiety|Nurse's Role
Interventions: BEHAVIORAL: Buzzy|BEHAVIORAL: Music video listening|BEHAVIORAL: Buzzy+ Music video listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Increasing Dialysate Magnesium on Calcification Propensity in Subjects on Haemodialysis
Status: COMPLETED
Conditions: Endstage Renal Disease
Interventions: OTHER: Dialysate magnesium (1.0 mmol/L)|OTHER: Dialysate magnesium (0.5 mmol/L)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subthreshold Micropulse Laser Treatment of Acute Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Acute Central Serous Retinopathy With Subretinal Fluid
Interventions: PROCEDURE: Micropulse laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Irinotecan|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Body-mass Index on the Outcome of Spinal Anesthesia for Total Knee Replacement Arthroplasty
Status: COMPLETED
Conditions: Spinal Anesthesia|Success or Failure of Spinal Anesthesia
Interventions: DRUG: Spinal anesthesia (heavy bupivacaine)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria
Status: WITHDRAWN
Conditions: Dysarthria|Huntington Disease
Interventions: OTHER: Study of dysarthria in patients with Huntington's disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Immunotherapy With Chemotherapy for Stage I-IIIB Non-Small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Velcade|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery
Status: RECRUITING
Conditions: Spinal Fusion|Spine Disease|Spinal Stenosis|Erector Spinae Plane Block
Interventions: DRUG: 0.9% Sodium Chloride Injection|DRUG: Dexamethasone 4 Mg/mL Injectable Solution|DRUG: Dexmedetomidine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Rate and/or Presence of Dextrose on the Labor Course of Nulliparas
Status: COMPLETED
Conditions: Length of Labor|Second Stage of Labor|Intravenous Hydration of Labor
Interventions: OTHER: Dextrose|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injectable Collagenase and Percutaneous Needle Fasciotomy for Dupuytren's Contracture
Status: COMPLETED
Conditions: Dupuytrens Contracture
Interventions: DRUG: Xiapex|PROCEDURE: Percutaneous needle fasciotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Resisitive Index as an Indicator of the Progression of Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DIAGNOSTIC_TEST: renal arterial resistive index|DIAGNOSTIC_TEST: uric acid level|DIAGNOSTIC_TEST: serum urea and creatinine|DIAGNOSTIC_TEST: 24 hours urinary proteins|DIAGNOSTIC_TEST: lipogram|DIAGNOSTIC_TEST: HbA1c level|DIAGNOSTIC_TEST: urine analysis|DIAGNOSTIC_TEST: abdominal ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination of Oral Fludarabine, Mitoxantrone Und Rituximab Induction Therapy and Rituximab Maintenance Therapy in Follicular B-Cell Lymphoma
Status: COMPLETED
Conditions: Follicular T-NHL Lymphoma|Rituximab Maintenance
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: DREAMS-OT Trial: Delirium Reduction Through Early Activation in Motivating and Sleep Promoting Routines: A Randomized Controlled Trial of Occupational Therapy for ICU Patients After Coronary Artery Bypass Graft (CABG) Surgery
Status: NOT_YET_RECRUITING
Conditions: Delirium, Postoperative
Interventions: OTHER: DREAMS-OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effects of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Apnea|Sleep Apnea, Obstructive|Sleep Disorder|Sleep Apnea Syndromes
Interventions: DEVICE: Hypoglossal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 3D Printed Foot Orthoses With Prefabricated Foot Orthoses
Status: COMPLETED
Conditions: Flexible Flatfoot
Interventions: DEVICE: 3D Printed Foot Orthosis|DEVICE: Prefabricated Foot Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Neuromuscular Exercise Therapy Program for Treatment of Wrist Osteoarthritis: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Osteoarthritis Wrist
Interventions: OTHER: Neuromuscular exercise therapy|OTHER: Training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Qvar Versus Clenil, a General Practice Research Database Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: extra fine particle hydrofluoroalkane beclomethasone dipropionate via metered dose inhaler|DRUG: standard particle particle hydrofluoroalkane beclomethasone dipropionate via metered dose inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets.
Status: COMPLETED
Conditions: Post-Ischemic Stroke
Interventions: DRUG: Placebo|DRUG: dalfampridine-ER 7.5mg|DRUG: dalfampridine-ER 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating SARC-F, SARC-CalF, and Calf Circumference as Diagnostic Tools for Sarcopenia in Thai Older Adults: Results From a Nationwide Study
Status: COMPLETED
Conditions: Sarcopenia|Diagnosis
Interventions: DIAGNOSTIC_TEST: SARC-F Questionnaire|DIAGNOSTIC_TEST: Calf Circumference Measurement|DIAGNOSTIC_TEST: SARC-CalF Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of DC-CIK Combined With Chemotherapy for Advanced Solid Tumor
Status: RECRUITING
Conditions: Solid Tumor
Interventions: COMBINATION_PRODUCT: DC-CIK combined with Chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Velcade, Decadron, and Doxil Followed by Cyclophosphamide in Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: dexamethasone|DRUG: liposomal doxorubicin|DRUG: cyclophoshamide|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy Effect as Preventive Measure for Oral Mucositis in Children With Hematological Malignancies
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: Laser therapy|DEVICE: Mock treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Stage 2 Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: amlodipine/losartan|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Effectiveness and Safety of Belotero Balance® Injection for Volume Augmentation of the Infraorbital Hollow
Status: COMPLETED
Conditions: Correction of Volume Loss in the Infraorbital Hollow Area
Interventions: DEVICE: Belotero Balance®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Oocyte Cryopreservation for Medical and Non Medical Indications
Status: COMPLETED
Conditions: Infertility, Female|Deferred Childbearing
Interventions: PROCEDURE: Investigational Oocyte Cryopreservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects
Status: TERMINATED
Conditions: Healthy Volunteers|Hepatic Impairment of Moderate Child Pugh Category
Interventions: DRUG: MD1003
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phenomics in Autoimmune and Inflammatory Diseases
Status: COMPLETED
Conditions: Healthy Volunteer|Rheumatoid Arthritis|Ankylosing Spondylitis|Systemic Lupus Erythematosus/Antiphospholipid Syndrome|FMF|Cryopyrin-Associated Periodic Syndromes /TNF-receptor Associated Periodic Syndrome|Vasculitis|Uveitis|Myositis|Crohn's Disease|Ulcerative Rectocolitis|Type 1 Diabetes|Unclassified IAD Knee and/or Hip Arthritis, Muscular Dystrophy
Interventions: OTHER: 1: AID groups|OTHER: 2: Control groups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anlotinib Plus Immune Checkpoint Inhibitors for Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib plus the same Immune Checkpoint Inhibitors.|DRUG: Anlotinib plus the new Immune Checkpoint Inhibitors.|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enriched Eggs for Retina Health in Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetic Retinopathy|Type 2 Diabetes
Interventions: OTHER: Docosahexaenoic Acid and Lutein Enriched Eggs|OTHER: Regular Eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spine Position and Neural Sensitivity
Status: COMPLETED
Conditions: Sciatic Nerve|Postural Lordosis|Nerve Pain
Interventions: DIAGNOSTIC_TEST: Knee extension angle|DIAGNOSTIC_TEST: Straight Leg Raise|DIAGNOSTIC_TEST: Slump Test|DIAGNOSTIC_TEST: Extended slump test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotic Yogurt Supplement in Reducing Diarrhea in Patients With Metastatic Kidney Cancer Being Treated With Vascular Endothelial Growth Factor-Tyrosine Kinase Inhibitor
Status: COMPLETED
Conditions: Diarrhea|Metastatic Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DIETARY_SUPPLEMENT: Micronutrient-Fortified Probiotic Yogurt|DRUG: VEGF-TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Oral Fampridine-SR for the Treatment of Spasticity Resulting From Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Muscle Spasticity
Interventions: DRUG: Fampridine-SR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Fentanyl-TTS Compared to Weak Opioids in Patients With Moderate to Severe Chronic Cancer Pain Previously Treated With NSAIDS (Non-steroidal Anti-inflammatory Drugs).
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Fentanyl-TTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Epoetin Alfa in Treating Anemic Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Anemia|Head and Neck Cancer
Interventions: BIOLOGICAL: epoetin alfa|DRUG: cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Awakening Threshold Effects of Belsomra 10 mg and 20 mg to Placebo in Non-elderly Insomniacs
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Suvorexant 10 mg|DRUG: Suvorexant 20 mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Peripheral Artery Disease
Interventions: DIAGNOSTIC_TEST: Breath Condensate Collection|DIAGNOSTIC_TEST: clinical examination, spirometry|DIAGNOSTIC_TEST: blood monocyte assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Third Parties
Status: UNKNOWN
Conditions: Kidney Neoplasms|Renal Insufficiency|Renal Replacement Therapy
Interventions: PROCEDURE: Restored Kidney Transplant Between Third Parties
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effectiveness of the Use of Prosthesis With Trans-Obturator Way for the Correction of Anterior Prolapse
Status: COMPLETED
Conditions: Anterior Prolapse
Interventions: PROCEDURE: Traditional surgery|DEVICE: Perigee® prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENDO GIA Stapler With Duet Tissue Reinforcement System (TRS) Used in Pulmonary Resections
Status: TERMINATED
Conditions: Lung Disease
Interventions: DEVICE: Duet TRS|DEVICE: Endo GIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Virologic Efficacy in Cerebrospinal Fluid (CSF) and Neurocognitive State in Patients Infected by HIV-1 Long-term Treatment (> 3 Years) With Lopinavir / Ritonavir Monotherapy
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lumbar puncture (Lopinavir/ritonavir monotherapy)|DRUG: Lumbar puncture (HAART: Lopinavir/ritonavir + 2 NRTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel Plus S-1 in Patients With Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: nanoparticle albumin-bound paclitaxel|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Ability of 3D Fluorscopy in Aiding Accurate Syndesmotic Reduction Following Traumatic Ankle Injury
Status: COMPLETED
Conditions: Displaced Ankle Fractures
Interventions: DEVICE: 2D Fluoroscopy|DEVICE: 3D Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers
Status: RECRUITING
Conditions: Locally Advanced Bladder Carcinoma|Metastatic Bladder Carcinoma|Stage III Bladder Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Unresectable Bladder Carcinoma
Interventions: PROCEDURE: Assessment of Distress|OTHER: Consultation Visit|OTHER: Nutritional Assessment|OTHER: Questionnaire Administration|OTHER: Supportive Care|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of TEE-guided Non-fluid Limited Combined With Dobutamine on Hepatic Venous Blood Flow Spectrum
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Hepatectomy
Interventions: DRUG: Dobutamine hydrochloride, Injectable|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reduce Crohn's-Associated Diarrhea With Sodium Channel Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Crohn's Disease|Inflammatory Bowel Disease
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of a Single Oral Dose of BI 425809 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809|DRUG: Itraconazole|DRUG: BI 425809
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: MK0653A (ezetimibe [+] simvastatin)|DRUG: Comparator: atorvastatin|DRUG: Comparator: fluvastatin|DRUG: Comparator: lovastatin|DRUG: Comparator: pravastatin|DRUG: Comparator: rosuvastatin|DRUG: Comparator: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells in Early Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: 2 million hMSC/kg|BIOLOGICAL: 4 million hMSC/kg|BIOLOGICAL: 6 million hMSC/kg|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 AMG 386 in Comb. Paclitaxel for Subjects With Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: AMG 386|DRUG: AMG 386|DRUG: Paclitaxel|DRUG: AMG 386 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder
Status: RECRUITING
Conditions: REM Sleep Behavior Disorder
Interventions: DRUG: PXS-4728 (A)|DRUG: Matching Placebo (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Adding Spinal Anaesthesia to a General Anaesthetic Technique Influence Readiness for Discharge in Patients Having Hand Assisted Laparoscopic Live Donor Nephrectomy
Status: COMPLETED
Conditions: Surgery
Interventions: PROCEDURE: Bupivacaine and Diamorphine|PROCEDURE: Remifentanil, Propofol and Cistracurium|PROCEDURE: Bupivacaine and Rectus Sheath injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Perfusion of Colorectal Anastomosis Using FLuorescence AnGiography (FLAG-trial)
Status: COMPLETED
Conditions: Rectal Cancer|Sigmoid Cancer
Interventions: DEVICE: Fluorescence angiography with indocianyne green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI)
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: Ultrase® MT20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections.
Status: WITHDRAWN
Conditions: Fuchs' Endothelial Dystrophy
Interventions: DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Crossover Comparative Bioavailability and Food Effect Study of Two EMB-001 Formulations
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Original formulation EMB-001|DRUG: New formulation EMB-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin and Mineral Absorption From Milk and PBMAs
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition|Healthy
Interventions: OTHER: Dairy Milk|OTHER: Soy Milk|OTHER: Almond Milk|OTHER: Oat Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DRUG: Placebo|DRUG: sodium nitrite 45 mg|DRUG: sodium nitrite 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Thalidomide in Previously Treated Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of CKD-391(2)
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: CKD-391(2)|DRUG: CKD-331, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Veloderm for the Treatment of Split-thickness Skin Graft Donor Sites
Status: COMPLETED
Conditions: Split-thickness Skin Graft Donor Sites
Interventions: DEVICE: Crystalline cellulose simple occlusive dressing|DEVICE: Vaseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children
Status: RECRUITING
Conditions: Pediatric Solid Tumor, Unspecified, Protocol Specific
Interventions: DRUG: Ondansetron (Oral soluble film OR injections) ,Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Symptoms and Quality of Life in Patients With Implantable Cardiac Defibrillators (ICDs) and Their Caregivers
Status: COMPLETED
Conditions: Quality of Life|Implantable Cardiac Defibrillators|ICDs
Interventions: BEHAVIORAL: Quality of life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Remote Ischemic Preconditioning in the Cardiac Surgery
Status: COMPLETED
Conditions: Myocardium; Injury|Cardiac Surgical Procedures
Interventions: PROCEDURE: remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DIETARY_SUPPLEMENT: 0 mg placebo|DIETARY_SUPPLEMENT: 300 mg GSE|DIETARY_SUPPLEMENT: 600 mg GSE|DIETARY_SUPPLEMENT: 900 mg GSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IPF
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Glass-ionomer Cements: 2-year Follow-up
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Glass ionomer|OTHER: Glass ionomer cement|OTHER: -Glass ionomer-|OTHER: -Glass ionomer cement-
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Flow Controlled Ventilation in ARDS Associated With COVID-19
Status: UNKNOWN
Conditions: ARDS Associated With COVID-19
Interventions: DEVICE: Flow controlled ventilation (Evone-ventilator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CALS Patient Activated Learning System (PALS)
Status: COMPLETED
Conditions: Communication|Trust|Health Knowledge, Attitudes, Practice
Interventions: OTHER: The Patient Activated Learning System (PALS)|OTHER: WebMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Romiplostim to Treat Immune Thrombocytopenia (ITP) in Pediatric Patients
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura|Thrombocytopenia|Thrombocytopenia in Pediatric Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)|Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)|Thrombocytopenic Purpura|Immune Thrombocytopenia
Interventions: DRUG: Romiplostim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Pitavastatin in Hypercholesterolemic Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Oxidative Stress|Inflammation
Interventions: DRUG: pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease（NAFLD）
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: HSK31679 low dose|DRUG: HSK31679 medium dose|DRUG: HSK31679 high dose|DRUG: Placebo|DRUG: Ezetimibe 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Ex-vivo Pulmonary Perfusion System on the Microbiome of Lung Grafts and Their Inflammatory Reaction.
Status: RECRUITING
Conditions: Lung Transplant Failure
Interventions: DEVICE: EVLP|DEVICE: Cold preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Spontaneous Breathing Activity on Atelectasis Formation During General Anaesthesia
Status: COMPLETED
Conditions: Atelectasis
Interventions: OTHER: Spontaneous Breathing|OTHER: Pressure Controlled Ventilation|OTHER: Pressure Support Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adipose Tissue in Crohn´s Disease Fistulas
Status: COMPLETED
Conditions: Crohn Disease|Perianal Fistula|Tissue Transplantation
Interventions: PROCEDURE: Injection with freshly collected autologous adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-human Study With the Antibody-drug Conjugate SYD985 to Evaluate Safety and Efficacy in Cancer Patients
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: SYD985 (trastuzumab vc-seco-DUBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy to Treat Gluteus Medius Trigger Points
Status: TERMINATED
Conditions: Anterior Knee Pain Syndrome|Patellofemoral Pain Syndrome
Interventions: OTHER: Dry Needling|OTHER: Soft Tissue Mobilization|OTHER: Placebo Control|OTHER: Hip and core strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Pharmacokinetics, Safety, and Tolerability of XC-8
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: XC8 (histamine glutarimide)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Miller's Blade and Airtraq Laryngoscope in Children
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: DEVICE: Intubation with Miller's blade|DEVICE: Intubation with Airtraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Esomeprazole (D961H) Capsule and Loxoprofen Tablet After Repeated Oral Administration in Japanese Males
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esomeprazole (D961H)|DRUG: Loxoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma: A Pilot Randomized Controlled Trial
Status: RECRUITING
Conditions: Muscle Invasive Bladder Urothelial Carcinoma|Muscle-Invasive Bladder Carcinoma
Interventions: DRUG: gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: protein expression analysis|OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study Investigating Nonacog Beta Pegol (N9-GP) for Treatment and Prevention of Bleedings in Chinese People With Haemophilia B
Status: COMPLETED
Conditions: Haemophilia B
Interventions: DRUG: Nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery
Status: COMPLETED
Conditions: Gliosarcoma|Recurrent Glioblastoma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Targeted Molecular Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 4-week, Randomized, Placebo-Controlled, Double-Blind, Efficacy and Safety Study of HS-25 in Adults With Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: HS-25|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: How Does Bariatric Surgery Affect Social Experiences and Well-being - The BaSES-study
Status: ENROLLING_BY_INVITATION
Conditions: Obesity
Interventions: PROCEDURE: Gastric bypass|PROCEDURE: Sleeve gastrectomy|PROCEDURE: Single anastomosis sleeve ileal (SASI) bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Phenformin in Combination With BRAF Inhibitor + MEK Inhibitor for Patients With BRAF-mutated Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Phenformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Energy Drink Ingredients on Cardiovascular Function in Men and Women 18-39 Years Old
Status: UNKNOWN
Conditions: Cardiac Arrhythmia|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Energy Drink Ingredients and Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Cisplatinum|DRUG: Docetaxel|DEVICE: Tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG Criteria
Status: TERMINATED
Conditions: Metastatic Cancer (Different Solid Tumour Types)
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of CHIKV VLP Vaccine PXVX0317 in Adults ≥65 Years
Status: COMPLETED
Conditions: Chikungunya Virus
Interventions: BIOLOGICAL: CHIKV VLP/adjuvant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Consuming Pork From Seaweed Extract Fed Animals on Antioxidant Status
Status: COMPLETED
Conditions: Antioxidant Status, Inflammation
Interventions: OTHER: Pork meat from pigs feed with a standard feed.|OTHER: Pork meat from pigs fed a feed with a Laminarin/fucoidan mix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of Two Glaucoma Drugs Over 24 Hours (0507A-137)(COMPLETED)
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: MK0507A, dorzolamide hydrochloride (+) timolol maleate|DRUG: Comparator: timolol maleate|DRUG: Duration of Treatment: Part 1) 6 wk timolol maleate run in|DRUG: Part 2) 6 wk washout pd Part 3) two 8 wk active tx pds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Albutein 5%|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FFA Hypertension and Inflammation in Lean and Obese Subjects
Status: COMPLETED
Conditions: Diabetes|Hypertension|Obesity
Interventions: OTHER: Intralipid 20%|OTHER: Normal Saline|OTHER: Oral fat load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sensory and Emotional Modulation of Dyspnea Under Artificial Ventilation in the Intensive Care Unit
Status: COMPLETED
Conditions: Dyspnea
Interventions: OTHER: Auditive stimulation|OTHER: Sensitive stimulation|OTHER: Auditory control|OTHER: Sensitive control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TAP and Laparoscopic and Robotic Gynecologic Procedures and Obese Women
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Ropivacaine 0.5% 20cc injectate bilaterally|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment of Cetuximab and Paclitaxel in Basal Like Breast Carcinoma
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: cetuximab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmocokinetic/Pharmacodynamic (PK/PD) Study of the Combination Cetuximab/Gefitinib
Status: COMPLETED
Conditions: Colorectal Cancer|Head and Neck Cancer|Non Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Cetuximab/Gefitinib combination and/or monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Peak Tidal Inspiratory Flow in Infants With Moderate to Severe Acute Viral Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DEVICE: Measurement of the peak tidal inspiratory flow (PTIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Huaier Granule for Prevention of Recurrence and Metastasis of Stage II and III Non-small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Huaier Granule|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Karolinska Interventional Study of Mammograhic Density (Karisma-1)
Status: COMPLETED
Conditions: Breast Cancer|Mammographic Density
Interventions: DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma
Status: TERMINATED
Conditions: Advanced Carcinoma|Non-small Cell Lung Cancer
Interventions: DRUG: Aflibercept|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dairy and Inflammation Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammation|Overweight and Obesity|Cardiometabolic Risk
Interventions: OTHER: Dairy Foods (Yoghurt, Cheese, Milk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of AI201901 in Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Allergens
Interventions: DRUG: AI201901|DRUG: Azelastine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Evaluating the Pharmacokinetics of DMB-3111 and Trastuzumab in Healthy Japanese Male Adults
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: DMB-3111|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical Periodontitis
Status: UNKNOWN
Conditions: Postoperative Pain|Apical Periodontitis
Interventions: DEVICE: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pain Neuroscience Education and Gradual Exposure to Exercise in Factory Workers With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Pain Neuroscience Education and gradual exposure|OTHER: Pilates and postural education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma
Status: UNKNOWN
Conditions: Newly Diagnosed Glioblastoma
Interventions: BIOLOGICAL: AV-GBM-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bone Mineral Density in Women With Breast Cancer Treated With Triptorelin and Tamoxifen or Exemestane on Protocol IBCSG 25-02
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Osteoporosis
Interventions: OTHER: laboratory biomarker analysis|PROCEDURE: dual x-ray absorptiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Patient-Ventilator Asynchrony Analysis Function
Status: NOT_YET_RECRUITING
Conditions: To Study the Incidence of Patient-ventilator Asynchronization in Two Groups of Patients Under Two Conditions With PVA Unsynchronization Analysis Function
Interventions: DEVICE: PVA recognition function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumours
Status: COMPLETED
Conditions: Unresectable Solid Tumor|Metastatic Solid Tumor|Locally Advanced Solid Tumor
Interventions: DRUG: RC118 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT