pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BATHE Method on Preoperative Anxiety, Patient Satisfaction and Individual Anesthesia Concerns
Status: COMPLETED
Conditions: Anesthesia; Reaction|Anxiety Preoperative|Patient Satisfaction
Interventions: OTHER: Bathe anamnesis method|OTHER: standart anamnesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly
Status: COMPLETED
Conditions: Elderly|Sedentary
Interventions: OTHER: Regional Specific Training Stimulus (RSTS)|OTHER: Aerobic Exercise Regimen (AE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Extension Study of the Safety and Clinical Utility of IPX066 in Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: IPX066 95 mg|DRUG: IPX066 145 mg|DRUG: IPX066 195 mg|DRUG: IPX066 245 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation in Autoimmune-Related Retinopathy(ARRON)
Status: TERMINATED
Conditions: Retinal Disease
Interventions: BIOLOGICAL: Hematopoietic stem cell transplantation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefits of the Use of a Support Bra in Women Undergoing Coronary Artery By-Pass Graft Surgery
Status: COMPLETED
Conditions: Quality of Life|Wound Complications|Pain
Interventions: DEVICE: control|DEVICE: surgical support bra|DEVICE: common support bra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Zevalin Versus Zevalin and Motexafin Gadolinium in Patients With Rituximab-Refractory Low-grade or Follicular B-cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Y-90-Zevalin|DRUG: Moxtezafin Gadolinium|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loratadine for Improvement of Bone Pain in Patients With Chronic Granulocyte-Colony Stimulating Factor (G-CSF) Use
Status: TERMINATED
Conditions: Bone Pain
Interventions: DRUG: Loratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinadizole on Treatment Helicobacter Pylori
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Doxycycline|DRUG: Levofloxacin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel + Carboplatin + Durvalumab With or Without Oleclumab for Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: MEDI4736|DRUG: MEDI9447
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Versus Routine Shunting in Carotid Endarterectomy Patients
Status: COMPLETED
Conditions: Stenoses, Carotid Artery
Interventions: PROCEDURE: Carotid endarterectomy with routine shount|PROCEDURE: Carotid endarterectomy with selective shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Bone Tumors|Small Round-cell Sarcomas
Interventions: DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome|SARS-CoV-2|COVID|COVID-19|Severe Acute Respiratory Syndrome
Interventions: DRUG: Valsartan (Diovan)|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Comparing The Pharmacokinetics of A Pregabalin Controlled Release Tablet 300mg With Immediate Release Formulation and to Assess the Effect of High Fat Diet in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lyrica|DRUG: Experimental drug|DIETARY_SUPPLEMENT: High fat meal|DIETARY_SUPPLEMENT: fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrectomy Study: Study to Investigate the Effect of Creon 25000 Minimicrospheres on Body Mass Index (BMI) in Patients After Gastrectomy
Status: COMPLETED
Conditions: Gastrectomy
Interventions: DRUG: Pancreatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OVCA-NAC-P2: Study of Chemotherapy Followed by Cytoreductive Surgery for Ovarian, Tubal and Peritoneal Cancers: JCOG0206
Status: COMPLETED
Conditions: Ovarian Neoplasms|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Neoadjuvant chemotherapy (Paclitaxel and Carboplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Stellate Ganglion Block and / or Reserpine in Group 2 Pulmonary Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Artery Hypertension
Interventions: DRUG: reserpine|PROCEDURE: stellate ganglion block|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of HIV-1 gp120 C4-V3 Hybrid Polyvalent Peptide Immunogen Mixed in Mineral Oil Containing Mannose Mono-Oleate (IFA)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 C4-V3 Polyvalent Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Losartan and Perindopril in Blacks Type 2 Diabetics Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Perindopril Arginine|DRUG: Losartan Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BXQ-350 Pharmacokinetic/Pharmacodynamic Study in Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuropathy;Peripheral|Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: BXQ-350|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Caries Sealing Using Giomer and Glass Ionomer Cement With or Without Silver Diamine Fluoride
Status: UNKNOWN
Conditions: Caries, Dental|Caries Class I
Interventions: DEVICE: SDF|DEVICE: Giomer|DEVICE: GIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Lenvatinib for Perioperative Treatment of Resectable Primary Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Resectable Hepatocellular Carcinoma
Interventions: DRUG: Tislelizumab combined with Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Remifentanil for Labor Analgesia
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Hydromorphone|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is There a Correlation Between Surgical Technique for Primary Anterior Cruciate Ligament Surgery and the Risk of Subsequent Formation of Fibrous Cyst (Cyclops) in the Knee Joint, Which Leads to the Need for Surgical Removal of the Cyclops?
Status: COMPLETED
Conditions: Cyclop Arthrofibrosis Anterior Cruciate Ligament
Interventions: PROCEDURE: Patients with Cyclop lesion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
Status: UNKNOWN
Conditions: Interstitial Cystitis|Painful Bladder Syndrome
Interventions: PROCEDURE: Bladder Thermal Distention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chest Physiotherapy on the Development of Preterm Infants.
Status: RECRUITING
Conditions: Development, Infant|Respiratory Distress Syndrome in Premature Infant
Interventions: OTHER: Group I (GE-I) - Stimulation of "reflex rolling" from the Vojta method|OTHER: Group II (GE-II) - expiratory flow increase technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Game Supported Breastfeeding Self-Efficacy, Breastfeeding Success
Status: COMPLETED
Conditions: Self Efficacy|Breast Feeding, Exclusive
Interventions: OTHER: Web Based Breastfeeding Education and Counseling with Digital Game Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of JUVÉDERM® VOLUMA® With Lidocaine for Improvement of Volume and Aesthetic Appearance of the Nose in Chinese Adults
Status: COMPLETED
Conditions: Nose Enhancement
Interventions: DEVICE: JUVÉDERM® VOLUMA® with Lidocaine|OTHER: No-treatment control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIRROR Project 44 - Rotator Cuff Repairs With or Without BioEnthesis™ Augmentation
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Surgery
Interventions: PROCEDURE: Rotator cuff repairs with BioEnthesis augmentation|PROCEDURE: Rotator cuff repairs without BioEnthesis augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth and Tolerance of Young Infants Fed Infant Formula
Status: COMPLETED
Conditions: Growth and Tolerance
Interventions: OTHER: Control Infant Formula|OTHER: Experimental Infant Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Anesthetic Technique on NK Cells
Status: ENROLLING_BY_INVITATION
Conditions: Pain|Anesthesia|Cancer
Interventions: DRUG: Bupivacaine + Fentanyl|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: bevacizumab|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Tralokinumab in Adults With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Placebo Q2W|BIOLOGICAL: Tralokinumab 300 mg, Q2W|OTHER: Placebo, Q2/4W|BIOLOGICAL: Tralokinumab 300 mg, Q2/4W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose Escalation Study of Eribulin Plus Weekly Carboplatin for Metastatic Breast Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Eribulin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Natural Orifice Transgastric Endoscopic Cholecystectomy With Laparoscopic Assistance
Status: WITHDRAWN
Conditions: Cholecystectomy
Interventions: DEVICE: NOTES GEN 1 Toolbox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Right-stellate Ganglion Block in Preventing Postoperative Nausea and Vomiting in Gynecological Laparoscopic Patients
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: PROCEDURE: Right-stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Tecar Therapy in Patients With Chronic Achilles Tendinopathy
Status: UNKNOWN
Conditions: Achilles Tendinopathy
Interventions: OTHER: Tecartherapy|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Pneumotachograph (SPI) for the Production of PET and CT Acquisitions Synchronized With Breath for the Assessment of Extension of Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Lung Nodule
Interventions: DEVICE: PET/CT 4D imaging in a synchronized mode centered on the thorax.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Evaluate the Improvement of Chronic Low-grade AEs in Patients With Ph+ CML With Optimal Response to Imatinib When Switched to Nilotinib
Status: TERMINATED
Conditions: Philadelphia Positive (Ph+) Chronic Myeloid Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myofascial Pain Syndrome in Patients With Breast Cancer-related Lymphedema
Status: RECRUITING
Conditions: Myofascial Pain Syndrome|Breast Cancer|Breast Cancer Female|Lymphedema|Lymphedema of Upper Limb|Pain
Interventions: DIAGNOSTIC_TEST: Diagnostic Criteria of Myofascial Pain Syndrome|DIAGNOSTIC_TEST: The Physical Examination of Trigger Points and Pain-Pressure Threshold Measurement With an Algometer|DIAGNOSTIC_TEST: Hand Grip Test|DIAGNOSTIC_TEST: VAS|DIAGNOSTIC_TEST: Quick DASH|DIAGNOSTIC_TEST: Lymqol-Arm|DIAGNOSTIC_TEST: Range of Motion of Shoulde Joint
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Physiologic Oxygen Tension on Clinical In Vitro Fertilization Outcomes
Status: COMPLETED
Conditions: Pregnancy|Infertility
Interventions: PROCEDURE: Atmospheric oxygen tension|PROCEDURE: Physiologic oxygen tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Five Days Quadruple and Clarithromycin Containing Triple Therapy as Treatment for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Quadruple therapy|DRUG: Triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Misoprostol Versus Bilateral Uterine Artery Ligation in Decreasing Blood Loss in Trans-abdominal Myomectomy
Status: UNKNOWN
Conditions: Vaginal Misoprostol and Bilateral Uterine Artery Ligation in Decreasing Blood Loss in Trans-abdominal Myomectomy
Interventions: DRUG: preoperative vaginal misoprostol|PROCEDURE: bilateral uterine artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Treatment of Benign Biliary Strictures and Cystic Duct Leakages With a Novel Biodegradable Biliary Stent
Status: COMPLETED
Conditions: Biliary Tract Diseases
Interventions: DEVICE: Endoscopic insertion of biodegradable biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients
Status: COMPLETED
Conditions: Chest Pains
Interventions: PROCEDURE: 64 multi-detector computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of an Antisense Product in Prostate, Ovarian, NSCL, Breast or Bladder Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: OGX-427|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Teriparatide 40-mcg subcutaneous injection|DRUG: Denosumab Injection|DRUG: Alendronate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DEVICE: Low energy shock wave|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 8-week Randomized, Open-label Study to Evaluate Food Effect on Efficacy and Safety of Oral Aliskiren 300 mg in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright White Light Therapy for the Improvement of Sleep, Fatigue, Distress, Depression, and Anxiety in Hospitalized Leukemia Patients
Status: COMPLETED
Conditions: Acute Leukemia|Recurrent Leukemia|Refractory Leukemia
Interventions: OTHER: Best Practice|PROCEDURE: Bright White Light Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: CO-1.01|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Twelve Week Study of Prototypes Mouth Rinses
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Colgate Cavity Protection Toothpaste|OTHER: Zero Alcohol Gum Prototype|OTHER: Alcohol Gum Prototype|OTHER: Listerine Cool Mint Antiseptic Mouthwash|OTHER: 5% Hydroalcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Following Irrigation With Endodontic Needle, Sonic and Passive Ultrasonic Techniques
Status: UNKNOWN
Conditions: Tooth,Non-vital
Interventions: DEVICE: conventional needle irrigation|DEVICE: passive ultrasonic irrigation|DEVICE: sonic irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systems Analysis and Improvement Approach to Prevent TB
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis|TPT|TB - Tuberculosis
Interventions: OTHER: Systems Analysis and Improvement Approach for TB (SAIA-TB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testosterone Replacement in Older Men and Atherosclerosis Progression
Status: COMPLETED
Conditions: Hypogonadism|Atherosclerosis
Interventions: DRUG: Testosterone Gel (Androgel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: RO7239361|DRUG: Placebo for RO7239361
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Catheter Securement Dressings for the Prevention of Cvc-related Bloodstream Infections in Cancer Patients
Status: COMPLETED
Conditions: Bloodstream Infection
Interventions: DEVICE: 3M™ Tegaderm™ CHG IV and 3M™ Tegaderm™ Advanced IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Selective Reporting for Antibiotic Susceptibility Testing and GPs' Prescribing of Broad-spectrum Antibiotics in Women With E. Coli UTIs
Status: RECRUITING
Conditions: Urinary Tract Infections
Interventions: OTHER: Dissemination of a selective reporting for antibiotic susceptibility testing|OTHER: Standard antibiotic susceptibility testing report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fosamprenavir in Pts With Hepatic Impairment
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Intervention A Standard dose|DRUG: Intervention B Reduced Dose|DRUG: Intervention C|DRUG: Intervention D|DRUG: Intervention E
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody, Combination Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory B-Cell Cancer
Status: UNKNOWN
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cytarabine|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: indium In 111 LL2 IgG|RADIATION: yttrium Y 90 epratuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetic Profile of a Collagen Bupivacaine Implant in Men After Open Mesh Herniorrhaphy
Status: COMPLETED
Conditions: Postoperative Pain|Inguinal Hernia
Interventions: DRUG: Bupivacaine Collagen Sponge|DRUG: placebo collagen sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INCB028050 Compared to Background Therapy in Patients With Active Rheumatoid Arthritis (RA) With Inadequate Response to Disease Modifying Anti-Rheumatic Drugs
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: INCB028050|DRUG: INCB028050|DRUG: INCB028050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of ALN-RSV01 in Lung Transplant Patients Infected With Respiratory Syncytial Virus (RSV)
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALN-RSV01|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitality Acupunch Exercise Program for Sarcopenia Older Adults
Status: COMPLETED
Conditions: Activities of Daily Living|Functional Fitness
Interventions: OTHER: Vitality acupunch (VA) exercise program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PSMA-PET Imaging in Patients With Metastatic Prostate Cancer: Institutional Evaluation of Detection Yield Performance and Reproducibility
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: PSMA -PET/CT scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Status: WITHDRAWN
Conditions: Lennox-Gastaut Syndrome
Interventions: DRUG: melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Angiomax to Heparin With Protamine in Patients Undergoing Cardiopulmonary Bypass (CPB)
Status: COMPLETED
Conditions: Cardiovascular Disease|Coronary Artery Bypass Surgery
Interventions: DRUG: Heparin|DRUG: Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Diagnostic Efficiencies of CEUS and EOB-MRI in Patients With High Risk of HCC
Status: COMPLETED
Conditions: Hepatocellular Cancer|Liver Cirrhoses|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Diagnostic CEUS and EOB-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lumen-apposing Metal Stent With or Without Coaxial Plastic Stent for Treatment of Walled-off Pancreatic Necrosis
Status: COMPLETED
Conditions: Pancreatitis, Acute Necrotizing|Walled Off Necrosis
Interventions: PROCEDURE: EUS-guided drainage using LAMS with DPS|PROCEDURE: EUS-guided drainage using LAMS alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on Opioid-induced Constipation in Patients With Cancer
Status: COMPLETED
Conditions: Opioid-induced Constipation in Patients With Cancer
Interventions: OTHER: Electroacupuncture group|OTHER: Sham electroacupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Acute Lymphoblastic Leukemia, Adult|B-cell Lymphoma Refractory|B-cell Lymphoma Recurrent
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: CD19-CD34 CAR transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Assisted Puncture of AV Fistulas in Chronic Hemodialysis Patients
Status: WITHDRAWN
Conditions: Dialysis|Fistula
Interventions: DEVICE: Ultrasound-assisted puncture|OTHER: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Lu AG06474|DRUG: Placebo to Lu AG06474|DRUG: Ibuprofen|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Satisfaction and Long-term Anatomic Efficacy Study on Patients Who Underwent a Richter Intervention in the Obstetric and Gynecology Department of Foch Hospital Since 2008
Status: COMPLETED
Conditions: Genital Prolapse
Interventions: OTHER: Satisfaction assessment|OTHER: Quality of life|OTHER: Gynecological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection|SARS-CoV Infection|ARDS|Coronavirus
Interventions: BIOLOGICAL: Umbilical Cord Lining Stem Cells (ULSC)|OTHER: Placebo (carrier control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Preoperative Treatment With Enzalutamide, Alone or in Combination With Exemestane in Primary Breast Cancer
Status: COMPLETED
Conditions: Primary Breast Cancer ER+ve|Primary Breast Cancer AR+ve TNBN
Interventions: DRUG: Enzalutamide|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrient and Hormonal Profile and Muscle Protein Synthesis Response to Consuming Chicken
Status: NOT_YET_RECRUITING
Conditions: Effect of Food
Interventions: OTHER: Conventional Chicken|OTHER: Regenerative Chicken
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
Status: RECRUITING
Conditions: Solid Tumor|Haematological Malignancy
Interventions: DRUG: Alectinib|DRUG: Atezolizumab|DRUG: Entrectinib|DRUG: Trastuzumab in combination with pertuzumab|DRUG: Vemurafenib in combination with cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Repeat Dosing of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection
Status: COMPLETED
Conditions: Severe Hemophilia A
Interventions: DRUG: FRSW117
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Safety Study of ND0612 Administered as a Continuous SC Infusion in Advanced Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: ND0612
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting
Status: UNKNOWN
Conditions: PreDiabetes|Metabolic Syndrome, Protection Against
Interventions: BEHAVIORAL: DPPFit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients With Resectable Solid Tumor Malignancies
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: Epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Alcohol Dependence and Comorbid Bipolar Disorder
Status: COMPLETED
Conditions: Alcohol Dependence|Bipolar Disorder|Depression|Mania|Psychosis
Interventions: DRUG: Lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Faropenem|DRUG: Amoxicillin/clavulanic acid 500mg/125mg|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pregabalin Versus Combined Pregabalin and Milnacipran in Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia, Primary
Interventions: DRUG: Pregabalin 300mg|DRUG: Combined pregabalin 300mg and milancipran 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted Versus Standard Laparoscopic Approach for the Surgical Treatment of Deep Infiltrating Endometriosis
Status: UNKNOWN
Conditions: Endometriosis
Interventions: PROCEDURE: standard laparoscopic surgery|PROCEDURE: robot-assisted surgery|DIAGNOSTIC_TEST: assessment of sexual function|DIAGNOSTIC_TEST: assessment of bowel symptoms|DIAGNOSTIC_TEST: assessment of urinary symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma|Localized Non-Resectable Adult Hepatocellular Carcinoma|Stage III Childhood Hepatocellular Carcinoma|Stage IIIA Hepatocellular Carcinoma|Stage IIIB Hepatocellular Carcinoma|Stage IIIC Hepatocellular Carcinoma|Stage IV Childhood Hepatocellular Carcinoma|Stage IVA Hepatocellular Carcinoma|Stage IVB Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobile Phones in Cryptogenic Stroke Patients Bringing Single Lead ECGs to Detect Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation|Ischemic Stroke|Transient Ischemic Attack
Interventions: DEVICE: Single lead ECG device|DEVICE: 7-Day Holter monitor.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study About Extra Virgin Olive Oil "Coratina" in Mild Cognitive Impairment and Alzheimer's Disease Patients
Status: UNKNOWN
Conditions: Neurodegenerative Diseases
Interventions: DIETARY_SUPPLEMENT: EVOO-C|DIETARY_SUPPLEMENT: ROO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Postoperative Pain After Using Various Intracanal Medication in Patients With Necrotic Pulp
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: COMBINATION_PRODUCT: Silver nanoparticle/Calcium hydroxide|DRUG: Silver Nanoparticles in gel form|DRUG: Calcium Hydroxide Intracanal medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-Week, Double-Blind, Placebo-Controlled, Randomized Study of the Efficacy of 40 mg/Day KW-6002 in Parkinson's Disease Patients on Levodopa/Carbidopa
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: KW-6002 (istradefylline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Interventions for Young Adults With Hip Pain
Status: NOT_YET_RECRUITING
Conditions: Hip Dysplasia|Hip Pain Chronic|Hip Osteoarthritis|Hip Arthritis|Psychosocial Problem
Interventions: DEVICE: Cell Phone Based Cognitive Based Therapy (Pacifica App)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin B12 for Aromatase Inhibitors Associated Musculoskeletal Symptoms in Breast Cancer
Status: WITHDRAWN
Conditions: HR-positive Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin B12|OTHER: Blood collection|OTHER: Brief Pain Inventory - Short Form survey|OTHER: FACT-ES Trial Outcome Index (Version 4)|OTHER: Questionnaire to Assess Adherence to Aromatase Inhibitors|OTHER: Demographics Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Study in Healthy Volunteers to Characterise the Exposure of Fluticasone Furoate (FF), Vilanterol (VI) and Umeclidinium (UMEC) at Two Different Doses
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF 400 mcg|DRUG: UMEC 500 mcg|DRUG: UMEC 250 mcg|DRUG: VI 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis|Minimal Change Disease|Immunoglobulin A Nephropathy|IgA Vasculitis|Alport Syndrome
Interventions: DRUG: Sparsentan|DRUG: Sparsentan|DRUG: Sparsentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor
Status: COMPLETED
Conditions: Adverse Anesthesia Outcome
Interventions: DRUG: Etoricoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DOuble-Lumen Intubation With VIdeolaryngoscopy
Status: NOT_YET_RECRUITING
Conditions: Intubation Complication|Intubation; Difficult or Failed|Anesthesia|Videolaryngoscopy
Interventions: DEVICE: Videolaryngoscope|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy Study Comparing Hand-assisted Laparoscopic and Mini-incision Muscle Splitting Incision Living Donor Nephrectomy
Status: COMPLETED
Conditions: Living Donors
Interventions: PROCEDURE: Living donornephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of 18F-FMISO PET/CT and MRI Imaging to Explore Tissue Hypoxia and Arteriovenous Shunting in Subjects With Recurrent Glioblastoma Before and After Bevacizumab Treatment
Status: TERMINATED
Conditions: Recurrent Glioblastoma
Interventions: BIOLOGICAL: [18F]fluoromisonidazole|DRUG: Bevacizumab|RADIATION: positron emission tomography (PET/CT).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study
Status: RECRUITING
Conditions: Metastatic Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Unresectable Renal Cell Carcinoma
Interventions: BIOLOGICAL: Avelumab|DRUG: Axitinib|DRUG: Cabozantinib|BIOLOGICAL: Ipilimumab|DRUG: Lenvatinib|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|RADIATION: Stereotactic Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraportal or Intramuscular Site for Islets in Simultaneous Islet and Kidney Transplantation
Status: UNKNOWN
Conditions: Type 1 Diabetes|End Stage Renal Disease
Interventions: PROCEDURE: Intraportal islet transplantation|PROCEDURE: Intramuscular islet transplantation|PROCEDURE: Intramuscular transpl with stemcells|PROCEDURE: Kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tramadol vs Remifentanyl Patient Controlled Analgesia for Second Trimester Abortions
Status: COMPLETED
Conditions: Abortion,Induced
Interventions: DRUG: tramadol|DRUG: remifentanyl|DEVICE: patient contolled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome|Irritable Bowel Syndrome With Diarrhea|Irritable Bowel Syndrome With Constipation|Irritable Bowel Syndrome Mixed
Interventions: DIETARY_SUPPLEMENT: Personalized dietary intervention based on microbiome analysis|DIETARY_SUPPLEMENT: Low-FODMAP diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MINIject (MINI SO627) in Patients With Open Angle Glaucoma Using Single Operator Delivery Tool
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma, Open-Angle Glaucoma Eye
Interventions: DEVICE: MINIject CS627 implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study
Status: UNKNOWN
Conditions: Stable Angina|Unstable Angina|Non ST Elevation Myocardial Infarction|ST Elevation Myocardial Infarction|Myocardial Infarction Not Otherwise Specified
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NATURE 3.1_New Approach for the Reduction of REnal Uremic Toxins
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Healthy
Interventions: DIETARY_SUPPLEMENT: Symbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Semapimod for Treatment of Moderate to Severe Crohn's Disease 1 or 3 Days' Treatment Versus Placebo
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Semapimod|DRUG: Semapimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Clarithromycin and Flouroquinolones Based Regimens in H.Pylori Eradication in Covid-19 Era
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: ISF35
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Online Parenting Training
Status: COMPLETED
Conditions: Behavior Problem|Behavior, Child|Parents|Parent-Child Relations
Interventions: BEHAVIORAL: Communication Skills Training|BEHAVIORAL: eHealth GenPMTO|BEHAVIORAL: Written Referral Process|BEHAVIORAL: One Session Education about Resources|DIAGNOSTIC_TEST: Survey of Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Safety, Tolerability, and Efficacy of Aramchol Meglumine in Primary Sclerosing Cholangitis
Status: NOT_YET_RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Aramchol meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bronchial Artery Protection on Cough After Thoracoscopic Lobectomy
Status: COMPLETED
Conditions: Cough
Interventions: OTHER: Preoperative three-dimensional reconstruction and intraoperative protection of bronchial artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lansoprazole Intravenous 30 mg Specified Drug-use Survey [Hemostatic Effect/Rebleeding Rate]
Status: COMPLETED
Conditions: Gastric Ulcer, Duodenal Ulcer, Acute Stress Gastritis, and Acute Gastric Mucosal Lesions
Interventions: DRUG: Lansoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bread Structure and Postprandial Metabolic Responses
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: OTHER: Finely milled whole wheat-legume bread|OTHER: Less processed whole wheat-legume bread|OTHER: Less processed whole wheat bread|OTHER: White wheat bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION