pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Task Specific Timing and Coordination Exercise to Improve Mobility in Older Adults: Program to Improve Mobility in Aging
Status: COMPLETED
Conditions: Gait, Unsteady
Interventions: BEHAVIORAL: Strength training|BEHAVIORAL: Endurance training|BEHAVIORAL: Flexibility training|BEHAVIORAL: Task Specific timing and coordination training|BEHAVIORAL: Physical activity behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Surgery Neuroprotection Study in Elders
Status: COMPLETED
Conditions: Post-operative Cognitive Decline|Post-operative Delirium
Interventions: DRUG: Aspart insulin|DRUG: Normal saline|DEVICE: Intranasal mucosal atomizer device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Insulin and Olanzapine Study in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Controls
Interventions: DRUG: OLANZapine 2.5 MG|DRUG: Placebo|DRUG: Insulin Lispro 100 UNT/ML|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of NOSE-colectomy on Fertility and Quality of Life Among Patients With Colorectal Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Quality of Life
Interventions: PROCEDURE: Surgical procedures( conventional laparoscopic and NOSE technique) for the treatment of colorectal DIE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Emotional Freedom Techniques Application on Nurses
Status: RECRUITING
Conditions: Occupational Stress|Alert Fatigue, Health Personnel
Interventions: BEHAVIORAL: Emotional Freedom Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study in Cancer Patients With Hepatic Impairment to Evaluate the Pharmacokinetics and Safety of NKTR-102 (Etirinotecan Pegol)
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors in Patients With Hepatic Impairment
Interventions: DRUG: 145 mg/m2 NKTR 102|DRUG: 120 mg/m2 NKTR 102|DRUG: 50 mg/m2 NKTR 102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Docetaxel and Cisplatin in Patients With Metastatic or Locally Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cisplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Nutrition and Body Composition
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight|Weight Loss|Muscle Maintenance
Interventions: OTHER: Whole-Body Electromyostimulation|OTHER: Pilates|OTHER: Tai Chi|OTHER: Nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy in Treating Participants With Breast Cancer Before Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8
Interventions: RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Osteopathic Treatment in Cervical Whiplash.
Status: COMPLETED
Conditions: Whiplash Injury of Cervical Spine|Osteopathia|Quality of Life|Chronic Pain Syndrome
Interventions: OTHER: Osteopathic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natriuretic Effect of GLP-1in Healthy Non Obese Subjects
Status: COMPLETED
Conditions: Sodium Excretion by Urination
Interventions: DRUG: Synthetic GLP-1 (1.5 pmol/kg/min) dissolved in 500 ml 0.9% saline|OTHER: 500 ml 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PET-MRI Assessment of Early Tumor Response to Predict Outcomes of HPV-Positive Oropharynx Cancer Patients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma|Oropharynx Cancer
Interventions: RADIATION: Intensity modulated radiotherapy (IMRT)|DIAGNOSTIC_TEST: PET-MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products.
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: OTDN product 1|OTHER: OTDN product 2|OTHER: Tobacco Cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Minimally Invasive Closed Reduction and Internal Fixation With Screws for Distal Radius Fracture
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: closed reduction group|DEVICE: open reduction group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Use of Stem Cells for the Treatment of Covid-19
Status: COMPLETED
Conditions: Covid19|Pneumonia|Multiple Organ Failure|Corona Virus Infection
Interventions: BIOLOGICAL: MSC Treatment|BIOLOGICAL: Saline Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Periodontal Debridement on Leptin Levels in Obese
Status: COMPLETED
Conditions: Periodontitis|Obesity
Interventions: OTHER: Scaling and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Specific 3D Printed Diabetic Insoles to Reduce Plantar Pressure
Status: RECRUITING
Conditions: Diabetes
Interventions: DEVICE: standard of care insole|DEVICE: 3D Printed Insole - pressure based|DEVICE: 3D Printed Insole - FEA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Bioavailability of Methylprednisolone
Status: COMPLETED
Conditions: Methylprednisone Administration|Intranasal Administration|Intravenous Administration|Healthy Subjects
Interventions: DRUG: Evaluation of bioavailability of methylprednisolone succinate administered intravenously|DRUG: Evaluation of bioavailability of methylprednisolone succinate administered intranasally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of Immediate Hyperthermic Intravesical Chemotherapy Following TURBT
Status: COMPLETED
Conditions: Bladder Cancer|Hyperthermia|Chemotherapy Effect
Interventions: OTHER: Hyperthermic intravesical chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Methylprednisolone After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Sleeping Quality|Fatigue|Inflammatory Response
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy
Status: UNKNOWN
Conditions: Infertility
Interventions: PROCEDURE: Endometrial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 1
Status: COMPLETED
Conditions: Refractive Errors|Myopia
Interventions: DEVICE: Verofilcon A contact lenses|DEVICE: Nesofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: eptacog alfa (activated)|DRUG: vatreptacog alfa (activated)|DRUG: vatreptacog alfa (activated)|DRUG: vatreptacog alfa (activated)|DRUG: vatreptacog alfa (activated)|DRUG: vatreptacog alfa (activated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor-Specific Clonotype, Metabolic Profile, and PET/CT in Predicting Chemotherapy Response in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Chemotherapy|PROCEDURE: Computed Tomography|DRUG: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Periodic Leg Movements' Diagnosis in Spinal Cord Injury: Actigraphy as an Alternative for Polysomnography?
Status: RECRUITING
Conditions: Spinal Cord Injuries|Periodic Limb Movement Disorder
Interventions: PROCEDURE: PSG and actigraphy recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NAET® Testing Devices in Detection of Hypersensitivity to Cane Sugar
Status: COMPLETED
Conditions: Allergy|Fatigue|Hypoglycemia|Hyperglycemia|Indigestion
Interventions: PROCEDURE: NAET Testing Modalities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerability and Immunogenicity Study of FLUVAL P H1N1 Flu Vaccine of Omninvest in Children and Adolescents
Status: COMPLETED
Conditions: Novel 2009 Influenza H1N1|Influenza, Human
Interventions: BIOLOGICAL: Vaccination with Fluval P monovalent influenza vaccine|BIOLOGICAL: Vaccination with Fluval AB|BIOLOGICAL: Vaccination with Fluval AB Novo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Mobile Application Using the PRO-CTCAE to Improve Patients' Participation in Symptom Management During Treatment.
Status: UNKNOWN
Conditions: Neoplasms
Interventions: OTHER: ePRO-CTCAE application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: DRUG: methotrexate|DRUG: afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Window of Opportunity Study in Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: CAPEOX|DRUG: Pembrolizumab|DRUG: Capecitabine/ 5-FU|DRUG: Pembrolizumab|DRUG: CAPEOX/Pembrolizumab|DRUG: Pembrolizumab alone|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies
Status: UNKNOWN
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor|Hematologic Malignancies
Interventions: DRUG: CN202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information Provision and Consistency Framing to Increase COVID-19 Booster Uptake
Status: RECRUITING
Conditions: COVID-19|Vaccines
Interventions: BEHAVIORAL: Reminder that facilitates action|BEHAVIORAL: Consistency framing|BEHAVIORAL: Information provision about the uniqueness of the bivalent booster|BEHAVIORAL: Information provision about bivalent booster eligibility|BEHAVIORAL: Information provision about the severity of COVID-19 symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study to Assess Performance and Safety of SULFEX 13081.22 Nasal Spray in Patients With Dry or Irritated Nose
Status: UNKNOWN
Conditions: Dry Nose|Nose Irritation
Interventions: DEVICE: SULFEX 13081.22
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Selinexor|DRUG: Temozolomide (TMZ)|DRUG: Lomustine (CCNU)|RADIATION: Standard Fractionated Radiation therapy (RT)|DRUG: Bevacizumab|DEVICE: TTField|DRUG: Carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study
Status: COMPLETED
Conditions: Sudden Cardiac Death
Interventions: DEVICE: Ovatio DR and Ovatio VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Endobronchial Mesenchymal Stromal Cells in the Treatment of Chronic Lung Allograft Dysfunction
Status: RECRUITING
Conditions: Chronic Lung Disease|Lung Transplant Rejection
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Skin Picking With Cognitive-Behavioral Protocol in Individual and Group Format.
Status: COMPLETED
Conditions: Skin-Picking
Interventions: BEHAVIORAL: Rothbaum protocol in individual format|BEHAVIORAL: Rothbaum protocol in group format
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid On-Site Evaluation (ROSE) by Endosonographer: for Whom, When and by Whom?
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DIAGNOSTIC_TEST: Fine needle aspiration|DIAGNOSTIC_TEST: Rapid on-site evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of TEAS on the Quality of Early Recovery
Status: COMPLETED
Conditions: C.Delivery; Surgery (Previous), Gynecological|Inappropriate Device Stimulation of Tissue|Delayed Emergence From Anesthesia
Interventions: OTHER: TEAS|OTHER: Con|DRUG: propofol, remifentanil, vecuronium|OTHER: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Oral Sodium Bicarbonate Supplementation in Haemodialysis Patients (BicHD)
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DRUG: sodium bicarbonate 500mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Determine the Fed Bioequivalence of Reformulated OXY Tablets and Original OxyContin® (OXY) Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Reformulated OXY (oxycodone HCl)|DRUG: Original OxyContin® (OXY) (oxycodone HCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Trial Comparing the Efficacy and Safety of Insulin Degludec and Insulin Glargine 300 Units/mL in Subjects With Type 2 Diabetes Mellitus Inadequately Treated With Basal Insulin With or Without Oral Antidiabetic Drugs
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Vaginal Solutions in Preoperative Use
Status: UNKNOWN
Conditions: Vaginal Surgeries
Interventions: DRUG: The Chlorhexidine gluconate 0.05%|DRUG: 10% Povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of the Prescription of 10,000 Steps Per Day Using a Pedometer APP in the Body Composition of Overweight Adults
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Control Group (CG)|BEHAVIORAL: Intervention Group (IG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
Status: RECRUITING
Conditions: Opioid Use|Auriculotherapy|Pain, Abdominal|Cancer Pain
Interventions: DEVICE: NSS-2 BRIDGE|DEVICE: Sham NSS-2 BRIDGE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Endothelial Progenitor Cells (EPCs) and Type 2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes
Interventions: DRUG: Metformin|DRUG: Detemir|DRUG: Liraglutide|DRUG: Insulin Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: DRUG: Clarithromycin (Klacid SR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Celecoxib and Rosiglitazone in Treating Patients Who Are Undergoing Cystoscopic Surveillance for Early-Stage Noninvasive Carcinoma of the Bladder or Radical Cystectomy for Muscle-Invasive Carcinoma of the Bladder
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: celecoxib|DRUG: rosiglitazone maleate|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Combined Toripalimab in Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Toripalimab plus Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Pancreatic Cancer|Virus-associated Tumors|Non Small Cell Lung Cancer|Melanoma|Bladder Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Association atezolizumab + BDB001 + RT|DRUG: Association atezolizumab + BDB001+ RT|DRUG: Association atezolizumab + BDB001+ RT|DRUG: Association atezolizumab + BDB001 + RT|DRUG: Association atezolizumab + BDB001 + RT|DRUG: Association atezolizumab + BDB001 + RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Cladribine|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Massage on the Immune System of Preterm Infants
Status: COMPLETED
Conditions: Premature Birth|Stress
Interventions: OTHER: massage therapy|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Pain Relief After Cesarean Section: Is There a Role for the Quadratus Lumborum Block?
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus Lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Open-Label Study of Fruquintinib in Solid Tumors, Colorectal, and Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors|Metastatic Colon Cancer|Metastatic Breast Cancer|Triple Negative Breast Cancer|HER2-negative Breast Cancer|Hormone Receptor Positive Breast Carcinoma|Rectal Cancer
Interventions: DRUG: Fruquintinib (HMPL-013)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole Food, Plant-Based Nutrition on Chronic Kidney Disease With Proteinuria
Status: TERMINATED
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease, Stage 4|Proteinuria
Interventions: OTHER: whole food, plant-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy of incobotulinumtoxinA (Xeomin) in Relieving Symptoms of Restless Leg Syndrome.
Status: COMPLETED
Conditions: Restless Leg Syndrome
Interventions: DRUG: incobotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human Endostatin Combined With Temozolomide and Irinotecan in Recurrent Gliomas
Status: RECRUITING
Conditions: Glioblastoma, Recurrent|Lower Grade Glioma, Recurrent
Interventions: DRUG: recombinant human endostatin,temozolomide,irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Anesthesia and Perioperative Medicine
Status: NOT_YET_RECRUITING
Conditions: Perioperative Complication|Perioperative/Postoperative Complications|Anesthesia Morbidity|Anesthesia; Adverse Effect|Anesthesia Complication|Anesthesia; Reaction
Interventions: PROCEDURE: Anesthesia Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Doppler-guided Endoscopic Treatment in Peptic Ulcer Bleeding
Status: UNKNOWN
Conditions: Peptic Ulcer Bleeding
Interventions: DEVICE: Supplementary endoscopy with doppler-guided therapy|DRUG: IV. PPI|OTHER: Endoscopic treatment at primary endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UNAIR Inactivated COVID-19 Vaccine as Homologue Booster (Immunobridging Study)
Status: RECRUITING
Conditions: COVID-19 Pandemic|COVID-19 Vaccines|COVID-19 Virus Disease
Interventions: BIOLOGICAL: INAVAC (Vaksin Merah Putih - UA- SARS CoV-2 (Vero Cell Inactivated) 5 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TAP Block Efficacy After Lumbar Spine Surgery Through Anterior Approach: a Randomized, Placebo-controlled Study
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: ropivacaine plus clonidine|DRUG: Placebo|DEVICE: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overcoming Inactivity in Older Adults: Impact on Vascular Homeostasis
Status: COMPLETED
Conditions: Aging|Cardiology|Nitric Oxide
Interventions: BEHAVIORAL: Pedometer to Increase Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
Status: COMPLETED
Conditions: Wrinkles
Interventions: DEVICE: HA IDF II plus|DEVICE: HA IDF II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome
Status: TERMINATED
Conditions: Takotsubo Cardiomyopathy|Takotsubo Syndrome
Interventions: DRUG: Adenosine|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients?
Status: COMPLETED
Conditions: Covid-19 Patients
Interventions: PROCEDURE: biopsies of subcutaneous adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1 Study for Safety of ACHN-490
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACHN-490 Injection vs placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Hearing Aid Labeling on Speech Understanding Measures
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Audeo P hearing aid labeled as "Prescriptive"|DEVICE: Audeo P hearing aid labeled as "OTC"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage II Non-Hodgkin Lymphoma|Ann Arbor Stage III Non-Hodgkin Lymphoma|Ann Arbor Stage IV Non-Hodgkin Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAHP for Patients With HER2-positive Early Breast Cancer and Subsequent AHP Adjuvant tHerapy After Surgery
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: TAHP and AHP|DRUG: TAHP plus AC and AHP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Sildenafil Citrate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Carcinoma|Advanced Lung Non-Small Cell Carcinoma|Lung Non-Small Cell Carcinoma|Mismatch Repair Deficiency|Refractory Colorectal Carcinoma|Refractory Lung Carcinoma|Refractory Pancreatic Carcinoma|Stage II Pancreatic Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: DRUG: Danvatirsen|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 Brasil II)
Status: COMPLETED
Conditions: Coronavirus Infections|Pneumonia, Viral
Interventions: DRUG: Hydroxychloroquine + azithromycin|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea (OSA) Treated With a Potassium Channel Inhibitor
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: BAY2253651|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Vascular Puncture and Catheterization
Status: COMPLETED
Conditions: Vascular Access Complication|Ultrasound Therapy; Complications|Perioperative/Postoperative Complications|Cardiovascular Abnormalities
Interventions: BEHAVIORAL: dynamic|BEHAVIORAL: Regular-triangle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Nitrate and Healthy Older Adults
Status: COMPLETED
Conditions: Blood Pressure|Cognitive Change|Functional Capacity|Brain Metabolism
Interventions: DIETARY_SUPPLEMENT: Nitrate-rich beetroot juice|DIETARY_SUPPLEMENT: Nitrate-depleted beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease
Status: COMPLETED
Conditions: Mycobacterium Infections, Nontuberculous|Mycobacteria, Atypical
Interventions: DRUG: LAI plus multi-drug regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents
Status: RECRUITING
Conditions: Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer
Interventions: DRUG: Administration of ceralasertib|DRUG: Administration of ceralasertib in combination with olaparib|DRUG: Administation of ceralasertib in combination with durvalumab|DRUG: Administration of ceralasertib monotherapy|DRUG: Administration of ceralasertib and olaparib|DRUG: Administration of ceralasertib and durvalumab|DRUG: Administration of ceralasertib in combination with AZD5305|DRUG: Administration of ceralasertib in combination with carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Screening With Electrocardiogram for Unknown Atrial Fibrillation in 65 Years Old and Above People in Nursing Home
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: OTHER: electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide Plus Rituximab (R) in Non Follicular NHL
Status: UNKNOWN
Conditions: Indolent Non Hodgkin Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ozone on Airway Inflammation in Allergic Asthmatics Treated With Omalizumab
Status: TERMINATED
Conditions: Asthma|Allergy
Interventions: DRUG: omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Psoriasis Plaque Test Study With LEO 29102 Plus Calcipotriol, Ointment, in Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Ointment A: LEO 29102 2.5 mg/g plus calcipotriol 50 µg/g ointment|DRUG: Ointment B: LEO 29102 2.5 mg/g ointment|DRUG: Ointment C: Calcipotriol 50 µg/g ointment|DRUG: Ointment D: LEO 29102 2.5 mg/g plus calcipotriol 50 µg/g ointment|DRUG: Ointment G: LEO 29102 2.5 mg/g plus calcipotriol 50 µg/g ointment|DRUG: Daivonex® ointment|DRUG: Diprosone® ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparison of Physiologic Response With Rate Adaptive Pacing Driven by Minute Ventilation and Accelerometer
Status: UNKNOWN
Conditions: Chronotropic Incompetence
Interventions: DEVICE: Pacemaker sensor set to MV|DEVICE: Pacemaker sensor set to XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of rhuMAb VEGF to Treat Metastatic Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Cancer
Interventions: DRUG: rhuMAb VEGF (Bevacizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Irinotecan in 3 Line or More Therapy in Local Recurrence or Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Stage IIIB, IV, Recurrent, and Metastatic Breast Cancer
Interventions: DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and Glimepiride
Status: COMPLETED
Conditions: Type 2 Diabetes|Hypoglycemia
Interventions: DRUG: vildagliptin and metformin (combination)|DRUG: glimepiride|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m Clear Cell Renal Cancer
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of RAD001 in Combination w/Chemotherapy & Radiation in Patients With NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: RAD001 (in addition to standard radiation and chemotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: KRN330|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US/MRI Fusion Local Anestesia TransPerineal Prostate Biopsies for Detection of Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Transperineal biopsy|PROCEDURE: Transrectal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Mindfulness-Based Mandala Activity on Anxiety and Spiritual Well-Being Levels of Senior Nursing Students
Status: COMPLETED
Conditions: Anxiety|Nursing Caries|ART
Interventions: BEHAVIORAL: Mindfulness-based mandala activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: PROCEDURE: Doin with acupuncture|DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Polyphenols Found in Pomegranate and Olives Food Supplements on Postprandial Blood Glucose in Vivo.
Status: COMPLETED
Conditions: Hyperglycaemia
Interventions: OTHER: Control (109 g white bread)|DIETARY_SUPPLEMENT: Dose 1|DIETARY_SUPPLEMENT: Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-Dose Thalidomide as Adjuvant Therapy After Radiofrequency Ablation for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis Before Surgery Versus After Cord Clamping in Elective Cesarean Delivery - a Double-blind, Prospective, Randomized Placebo-controlled Trial
Status: COMPLETED
Conditions: Elective Cesarean Section
Interventions: DRUG: Keflex|DRUG: Keflex|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Adriamycin, vinblastine, and dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Airflow Obstruction, Chronic|Chronic Obstructive Airway Disease|Chronic Obstructive Lung Disease
Interventions: DEVICE: Noninvasive Open Ventilation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Efficacy and Safety of RsqVD Combination Therapy for Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: lenalidomide|DRUG: Subcutaneous bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Iron (Ferinject®) on Exercise Capacity and Quality of Life of Stable COPD Patients
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ferric carboxymaltose, Ferinject® 50mg Iron/ml Solution for Injection / Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Pyridoxine for Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia|Antipsychotic Agents
Interventions: DIETARY_SUPPLEMENT: Pyridoxine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Doxorubicin Hydrochloride|DRUG: Doxorubicin-Eluting Beads|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|DRUG: Mitomycin|OTHER: Pharmacological Study|OTHER: Placebo Administration|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DEVICE: magnetic seizure therapy (MST)|DEVICE: electroconvulsive therapy (ECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Blockade Improves Surgical Conditions
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: OTHER: Neuromuscular blockade with rocuronium and reversal with sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aflibercept (EYLEA)as Secondary or Third Line Treatment for Neovascular Age-related Macular Degeneration.
Status: UNKNOWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Aflibercept (EYLEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Efficacy of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) Who Have Completed Study 4658-102 (NCT03218995)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Eteplirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Root Proximity During Mini-Screw Insertion Using a Digital Three-Dimensional Printed Guide
Status: UNKNOWN
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: Three dimensional printed digital guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.
Status: TERMINATED
Conditions: Idiopathic Dilated Cardiomyopathy
Interventions: DRUG: Infusion of autologous mononuclear bone marrow cells|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Combined With PD-1 Inhibitors as First-line Treatment for Unresectable/Advanced Biliary Tract Carcinoma
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: Lenvatinib|DRUG: PD-1 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing to Support Oral AntiCoagulation Adherence in Patients With Non-valvular Atrial Fibrillation (MISOAC-AF)
Status: COMPLETED
Conditions: Patient Compliance|Patient Adherence
Interventions: BEHAVIORAL: Motivational interview|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comprehensive Magnetic Resonance of Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DRUG: Simvastatin|DRUG: Ezetimibe|DRUG: Simvastatin/Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD56+CD3- NK Cells Following Allogeneic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Haematological Malignancies|Allogeneic Stem Cell Transplant|CD56+CD3- NK Cells
Interventions: PROCEDURE: Infusion of donor derived ex-vivo selected NK cells to patients after transplant|PROCEDURE: Haematology / Blood chemistry sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT