pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: JOint Use of Database to Identify Risk Factors of CARDio-vascular Toxicity Induced by Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: Myocarditis|Cardiomyopathies|Heart Diseases|Cardiovascular Diseases|Pericarditis|Vasculitis
Interventions: DRUG: ICI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bispectral Index Monitoring During Testing in the Electrophysiology Lab
Status: TERMINATED
Conditions: Tachycardia, Ventricular
Interventions: DEVICE: Bispectral index monitoring|OTHER: Ramsey Sedation Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Metformin and Pioglitazone Effects on Adipokines Concentrations in Newly Diagnosed Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measles Vaccination at Health System Contacts
Status: ENROLLING_BY_INVITATION
Conditions: Measles Vaccine|Hospital Admission|Mortality|Non-specific (Heterologous) Effects of Vaccines
Interventions: BIOLOGICAL: measles vaccine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immediate Implant Placement: a Clinical and Radiographic Study on Hard and Soft Tissues Retraction at One Year.
Status: ENROLLING_BY_INVITATION
Conditions: Immediate Implant Placement|Guided Surgery|Immediate Tamporization
Interventions: OTHER: Immediate Implant Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Type 2 Diabetes Management With Lantus® (Malbec: Manejo Con Lantus® de Diabéticos Tipo 2)
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Cognitive Behavioural Treatment With Support on Communication and Information Technologies for the Management of Chronic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Rehabilitation treatment and information|BEHAVIORAL: cognitive behavioural therapy (CBT)|BEHAVIORAL: cognitive behaviour therapy supported by ICT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Baby Massage on Oral Motor Skills of Premature Babies
Status: COMPLETED
Conditions: Infant, Premature
Interventions: OTHER: Baby massage was applied to the intervention group (n=20) of the study|OTHER: Oral stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Fractional Booster Dose of COVID-19 Vaccines Available for Use in Pakistan/Brazil: A Phase 4 Dose-optimizing Trial
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Sinovac|BIOLOGICAL: AZD1222|BIOLOGICAL: BNT162b2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome
Status: WITHDRAWN
Conditions: Sjögren's Syndrome|Systemic Lupus Erythematosus|Rheumatoid Arthritis|Systemic Sclerosis|Ankylosing Spondylitis|Dry Eye Syndrome
Interventions: DIAGNOSTIC_TEST: Traditional Chinese Medicine pattern|DIAGNOSTIC_TEST: Traditional Chinese Medicine tongue diagnosis|DIAGNOSTIC_TEST: Traditional Chinese Medicine pulse diagnosis|DIAGNOSTIC_TEST: Heart rate variability|DIAGNOSTIC_TEST: Schirmer's test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Accuracy of Ferumoxytol-Enhanced MRI for Detecting Lymph Node Metastases in Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: Ferumoxytol|OTHER: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis
Status: RECRUITING
Conditions: Chronic Granulomatous Disease-associated Colitis
Interventions: DRUG: MTP 101-LF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Intervention to Increase Patient Preparedness and Satisfaction Trial (TIPPS): A Randomized Control Trial
Status: COMPLETED
Conditions: Prolapse|Stress Urinary Incontinence
Interventions: BEHAVIORAL: Preoperative telephone call three days before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating Patient Reported Outcomes in Radiation Therapy, The PRO-RT Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Head and Neck Carcinoma|Lung Carcinoma|Malignant Solid Neoplasm
Interventions: OTHER: Electronic Health Record Review|OTHER: Medical Device Usage and Evaluation|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics (PD) of GSK3888130B in Healthy Participants
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: GSK3888130B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity
Status: RECRUITING
Conditions: Obesity|Nonalcoholic Fatty Liver|Diabetes Type 2|Healthy
Interventions: OTHER: Dietary consultation weight loss intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess Long-term Feasibility of Reduced Dose Dasatinib in Chronic Phase Chronic Myeloid Leukemia Patients
Status: UNKNOWN
Conditions: Chronic Myelocytic Leukemia
Interventions: OTHER: RQ-PCR(Real-time Quantitative Polymerase chain reaction) RNA Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomised Controlled Study on the Use of Psychoeducation for Bulimia Nervosa in Young Women
Status: COMPLETED
Conditions: Bulimia Nervosa
Interventions: BEHAVIORAL: Guided Self-help for Bulimia nervosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety & Efficacy of the J-Valve Ausper System in Patients With Severe Aortic Stenosis and/or Aortic Regurgitation
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: DEVICE: J-Valve Transcatheter Aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Roll-over Study to Investigate the Efficacy and Safety of Adalimumab Given Long-term to Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab 40 mg subcutaneous (SC) every other week (EOW)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans
Status: COMPLETED
Conditions: Opioid Sensitivity|Individual Difference|Abuse Opioids
Interventions: DRUG: Within-subject test of blinded study medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Therapy With Paravertebral Oxygen-ozone Injections and Topical Cannabidiol and β-Caryophyllene Patch in Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: DRUG: Cannabidiol and β-Caryophyllene Patch|DEVICE: Oxygen-Ozone Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Metastatic Adenoid Cystic Carcinoma
Interventions: OTHER: Standard of Care|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myopericarditis After Messenger Ribonucleic Acid (mRNA) COVID-19 Vaccination in Children 5-11 Years Old
Status: UNKNOWN
Conditions: Myopericarditis|Myocarditis|Vaccination; Complications|COVID-19 Pandemic|SARS-CoV2 Infection
Interventions: BIOLOGICAL: Pfizer-BioNTech mRNA COVID-19 vaccination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic. Supplementation in Reducing the Risk of Kidney Stone in Adults With Recurrent Kidney Stone Colic or Acute Episode of Colicky Pain.
Status: NOT_YET_RECRUITING
Conditions: Recurrent Kidney Stones With Colicky Pain
Interventions: OTHER: MetProrenes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Alveolar Recruitment Strategies on Arterial Oxygenation and Postoperative Inflammatory Response During Laparoscopic Bariatric Surgery: A Randomised Control Trial.
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: protective lung strategy with recruitment manoeuvre (RM) - steady PEEP|PROCEDURE: protective lung strategy with recruitment manoeuvre (RM) - decreasing PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Food Effect on Bioavailability of Metformin/Gliclazide in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin/Gliclazide Fixed Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Sub-Study With Patients in APO401 to Evaluate Adverse Events During Dose Introduction in Apomorphine-naïve Patients.
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: apomorphine HCl injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Computer-assisted Cognitive Remediation in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia; Psychosis|Cognitive Impairment|Executive Function|Randomized Controlled Trial|Efficacy
Interventions: OTHER: Computer-assisted Cognitive Remediation|OTHER: Conventional training programmes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Mass Balance, Pharmacokinetics, Metabolism, and Excretion of Emraclidine in Healthy Adult Male Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Emraclidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion
Status: RECRUITING
Conditions: Ischemic Stroke, Acute|Thrombolysis|Endovascular Treatment
Interventions: DRUG: rhTNK-tPA|DEVICE: direct EVT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Stimulation With FSH Alone Versus FSH Plus GnRH Antagonist in an Oocyte Donor/Recipient Programme
Status: NOT_YET_RECRUITING
Conditions: Premature Luteinisation|Progesterone Elevation
Interventions: OTHER: GnRH antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19)
Status: TERMINATED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Tocilizumab (TCZ)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo|DRUG: Gliclazide|DRUG: Glimepiride|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Metabolic Syndrome|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: At Home REhabilitation and Monitoring of People in poST-covid Condition Through ARc-inTellicare Platform (RESTART/RICOMINCIARE)
Status: COMPLETED
Conditions: Post-COVID19|Parkinson Disease
Interventions: DEVICE: ARC intellicare
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Phase I/II Study of Panitumumab, Capecitabine and Oxaliplatin w EBRT for Esophageal Cancer
Status: COMPLETED
Conditions: Cancer of the Esophagus
Interventions: DRUG: Panitumumab|DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevention of Rh Disease of Newborns in Pakistan
Status: COMPLETED
Conditions: Rhesus Disease|Anti-D (Rh) Antibodies Affecting Care of Mother
Interventions: DRUG: RhIg prophylaxis|DEVICE: ELDONCARD|DIAGNOSTIC_TEST: ELDONCARD Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative, Randomized Study on the Anti-inflammatory and Regenerative Efficacy of a New Medical Device (DM) Based on Hydrolyzed Collagen Peptides in Patients With Femoro-acetabular Impingement Undergoing Hip Arthroscopy
Status: COMPLETED
Conditions: Femoroacetabular Impingement|Hip Arthroscopy|Hip Osteoarthritis|Hydrolyzed Collagen Peptides
Interventions: DEVICE: Class III medical Hydrolyzed Collagen Peptides PEP-52 (Peptys)|DRUG: Cortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: temozolomide|DRUG: veliparib|GENETIC: DNA methylation analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: proteomic profiling|OTHER: high performance liquid chromatography|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: pharmacogenomic studies|OTHER: pharmacological study|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Blood Levels of Tenofovir Disoproxil Fumarate in HIV Infected Pregnant Women and Their Babies
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir disoproxil fumarate|DRUG: Tenofovir disoproxil fumarate|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parallel Phase I/II Trial of Decitabine and Peg-Interferon in Melanoma: Phase I Portion
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Decitabine|DRUG: Pegylated Interferon Alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food-Based Intervention and Psychosocial Stimulation to Improve Growth & Development of < 24 Month Indonesian Children
Status: UNKNOWN
Conditions: Nutritional Anemia|Child Development
Interventions: OTHER: FBDG group|OTHER: Stimulation|OTHER: Combinded FBDG and stimulation|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Phase III Transition Study of DRL Rituximab to Reference Medicinal Products
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Experimental: Arm A: DRL_RI|BIOLOGICAL: Arm B: Rituxan®/Mabthera®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Cardiovascular Risk Service Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases|Personal Health Records|Pharmaceutical Care|Mobile Apps
Interventions: OTHER: Pharmacist-led cardiovascular risk service (CVRS)|OTHER: Mobile access to study Personal Health Record|OTHER: Web access to study Personal Health Record
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on the Correlation Between NAT2(N-acetyltransferase2) Gene Polymorphism and CrCl(Creatine Clreance) and the Efficacy and Safety of Levosimendan in Patients With Severe Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Levosimendan|Efficacy|Safety
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Identification of Candida in Intra-abdominal Candidiasis
Status: COMPLETED
Conditions: Candida Sepsis|Candidiasis, Invasive|Peritonitis Infectious|Critically Ill
Interventions: DIAGNOSTIC_TEST: calscreener|OTHER: Metabolic profile|OTHER: optical microscopy|OTHER: RTqPCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Status: RECRUITING
Conditions: Obstetric Pain
Interventions: PROCEDURE: Fentanyl 1|PROCEDURE: Fentanyl2|PROCEDURE: Fentanyl 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Placement in the Esthetic Zone
Status: UNKNOWN
Conditions: Unspecified Atrophy of Edentulous Alveolar Ridge
Interventions: PROCEDURE: Immediate implant placement with simultaneous bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOX Combined With Tislelizumab and LDRT for Neoadjuvant Treatment of Locally Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: SOX+Tislelizumab+LDRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Duolac 7S Administration on Improving Symptom in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Duolac7S|DIETARY_SUPPLEMENT: starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacokinetic Properties of FIAsp in Children, Adolescents and Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment
Status: RECRUITING
Conditions: Bone Cancer|Articular Disease|Infectious Disease
Interventions: DIAGNOSTIC_TEST: 18F-sodium fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Predictive Factors of Cardiac and Cerebral Involvement in TMA
Status: COMPLETED
Conditions: Thrombotic Microangiopathies|Thrombotic Thrombocytopenic Purpura
Interventions: OTHER: Biological and imaging investigations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EMOTIon and COgNitive Function After Atrial Fibrillation Catheter Ablation vs. Medical Therapy(EMOTICON Trial)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Atrial fibrillation catheter ablation group|DRUG: Medical therapy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasonex (Mometasone Furoate Nasal Spray) in Adenoids Hypertrophy in Children (P04367)
Status: COMPLETED
Conditions: Adenoids
Interventions: DRUG: mometasone furoate nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Multidimensional Dyspnea Profile (MDP)
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD Exacerbation|CHF|OSA|COPD
Interventions: DIAGNOSTIC_TEST: Multidimensional Dyspnea Profile
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ZEPHYR: A Study Evaluating Surgical Outcome After Implantation of the Zephyr ZSI 475 FTM Inflatable Penile Implant in the Neophallus After Female-to-male Sex Reassignment Surgery
Status: RECRUITING
Conditions: Erectile Dysfunction|Gender Dysphoria
Interventions: OTHER: Implantation of the Zephyr ZSI 475 FTM erectile implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of an Exercise Intervention on Taxane-induced Peripheral Neuropathy in Breast Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: CIPN - Chemotherapy-Induced Peripheral Neuropathy
Interventions: BEHAVIORAL: The home-based extremity exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery
Status: COMPLETED
Conditions: Pain, Acute|Surgery
Interventions: PROCEDURE: Ultrasound Guided ESP Block with Programmed Intermittent Bolus (PIB) for VATS|PROCEDURE: Ultrasound Guided ESP Block with Continuous Infusion (CI) for VATS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Description of Changes in NIRS as a Function of Ductus Arteriosus Status in Very Premature Babies Born Before 32 WG at the DIJON University Hospital
Status: RECRUITING
Conditions: Extremely Premature Newborn (Born Before 32 Weeks' Gestation)
Interventions: OTHER: Collection of brain and kidney NIRS measurements|OTHER: echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Low Blood Sugar With Glucagon Among Patients With Type 1 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Glucagon|OTHER: Isotonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-Domain Exercise and Memory in Adults Relative to ApoE Genotype: A fMRI Study
Status: RECRUITING
Conditions: Exercise Training|Executive Function|Aging
Interventions: BEHAVIORAL: Multi-Domain Exercise Program|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sitting Interruption and Whole-body Cardiovascular Health
Status: RECRUITING
Conditions: Sedentary Behavior|Sedentary Time
Interventions: BEHAVIORAL: One 5-Minute Walking Bout Each Hour|BEHAVIORAL: One 15-Minute Standing Bout Each Hour|BEHAVIORAL: One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour|BEHAVIORAL: Uninterrupted Sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effects of Multiple Doses of LY3372689 on the Brain in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3372689|DIAGNOSTIC_TEST: [18F]LSN3316612
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771|DRUG: PF-05089771
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant High-Dose Thiotepa and Stem Cell Rescue Associated With Conventional Chemotherapy in Relapsed Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome With Excess Blasts-2
Interventions: DRUG: AG-120|DRUG: Placebo for AG-120|DRUG: AG-221|DRUG: Placebo for AG-221
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laser Assisted Nonsurgical Periodontal Treatment
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: DEVICE: Ultrasonics|DEVICE: Gracey Curettes|DEVICE: Er:YAG Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study
Status: UNKNOWN
Conditions: Solid Tumors
Interventions: DRUG: HBM4003|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Golimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Almonertinib Plus Lastet for EGFR+ Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer Non-small Cell Stage IV
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Lamivudine Plus Stavudine or Zidovudine in HIV-Infected Patients Who Have Taken Zidovudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Salba on Weight Loss in Overweight Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Salba (Salvia hispanica L.)|DIETARY_SUPPLEMENT: Oat-based Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of the Combination of Niraparib and Dostarlimab (TSR-042) in Participants With Platinum Resistant Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multi-Centre, Study to Assess the Safety of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies.
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: BIOLOGICAL: MEDI4736 (Durvalumab)|BIOLOGICAL: MEDI4736 (Durvalumab) + Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Sildenafil Persistent Pulmonary Hypertension Of The Newborn
Status: WITHDRAWN
Conditions: Persistent Pulmonary Hypertension of the Newborn
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogenic Stem Cell Transplantation (SCT) With Non-myeloablative Conditioning in Patients With Relapse Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Ibritumomab Tiuxetan (Zevalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Gastric Precancerous Lesions by a Blood Test GastroPanel in Patients With Increased Gastric Cancer Risk
Status: COMPLETED
Conditions: Gastric Cancer|Gastric Precancerous Lesions
Interventions: OTHER: blood samples analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal Lesions
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Intravascular lithotripsy|PROCEDURE: Standard lesion preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation With and Without Delorme Technique of Progressive Resisted Exercises in Patients of Post PCI.
Status: RECRUITING
Conditions: Percutaneous CORONARY INTERVENTION
Interventions: OTHER: Standard Cardiac rehabilitation with Delorme technique|OTHER: standard cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel 75 mg/m2|DRUG: Docetaxel 60 mg/m2|DRUG: Radium-223
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Path Planning for Image-guided Needle Interventions
Status: COMPLETED
Conditions: Gastrointestinal Diseases|Bone Diseases|Muscular Diseases|Spinal Diseases|Vascular Diseases
Interventions: RADIATION: XperGuide|RADIATION: XperGuide with virtual path planning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tongxinluo Capsule in Ischemic Stroke Patients（TISS)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Tongxinluo capsule|DRUG: placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis
Status: RECRUITING
Conditions: Insulin Sensitivity|24-hour Glucose Control
Interventions: OTHER: HIgh UPF controlled diet|OTHER: No UPF controlled diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: DEVICE: Fraxel DUAL 1550/1927|DRUG: oral isotretinoin|DRUG: oral valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MADIT-CRT: Multicenter Automatic Defibrillator Implantation With Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Tachycardia|Congestive Heart Failure
Interventions: DEVICE: Cardiac resynchronization therapy with defibrillation|DEVICE: Implantable Cardioverter Defibrillator (ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Nausea and Vomiting in Children Submitted to Strabismus Surgery
Status: UNKNOWN
Conditions: Anesthesia|Strabismus|PONV
Interventions: DRUG: Palonosetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose, Double-Blind, Placebo and Active Controlled Study of Pharmacokinetics of Diractin® as Well as Safety and Efficacy for the Treatment of Muscle Soreness
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: DRUG: Diractin|DRUG: Diractin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Immunogenecity and Safety of VaccinemRNA-1273 in Elderly Volunteers (Over 65 y) Compared to Younger Ones (18-45y)
Status: UNKNOWN
Conditions: Prevention of COVID19
Interventions: BIOLOGICAL: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Osimertinib + Savolitinib|DRUG: Savolitinib + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Algorithm to Decide on Antibiotic Prescription in Lower Respiratory Tract Infection in Primary Care
Status: COMPLETED
Conditions: Lower Resp Tract Infection
Interventions: DIAGNOSTIC_TEST: UltraPro|DIAGNOSTIC_TEST: Procalcitonin|DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Naso-pharyngeal swab and sputum culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Efficacy and Safety of Favipiravir-HU
Status: TERMINATED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Interventions: DRUG: Favipiravir HU 200 mg hard capsules|DRUG: Placebo HU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: DRUG: Evolocumab 140mg/mL Injector 1milliliter (mL) Pen x 3 for a monthly dose of 420 mg for 12 months.|OTHER: Placebo 1 milliliter (mL) Injector Pen x 3 monthly for 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis
Status: RECRUITING
Conditions: ANCA Associated Vasculitis
Interventions: BIOLOGICAL: blood sample|BIOLOGICAL: urine sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: VerTouch Device: A Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Pregnancy|Pain
Interventions: DEVICE: Group #1: VerTouch utilized for identification of site for labor epidural or spinal anesthesia procedure|DEVICE: Group #2: Ultrasound (US) utilized for identification of site for labor epidural or spinal anesthesia procedure|OTHER: Group #3: Control group, palpation utilized for identification of site for labor epidural or spinal anesthesia procedure|DEVICE: Group #4: VerTouch utilized for identification of site for lumbar puncture procedure|DEVICE: Group #5: Ultrasound (US) utilized for identification of site for lumbar puncture procedure|OTHER: Group #6: Control group, palpation utilized for identification of site for lumbar puncture procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Treatment of Lower Leg Anterolateral Chronic Exertional Compartment Syndrome With Intra-muscular Botulinum Injections.
Status: NOT_YET_RECRUITING
Conditions: Chronic Exertional Compartment Syndrome
Interventions: BIOLOGICAL: Botulinum toxin A|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food Intake and Intra-Nasal Insulin for African American Adults (FIINAAL)
Status: COMPLETED
Conditions: Insulin
Interventions: DRUG: Insulin, Regular, Human|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single-injection Modified 4 in 1 Block as Postoperative Analgesia in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Ultrasound guided single injection modified 4 in 1 block technique|PROCEDURE: Ultrasound guided adductor canal block technique|DRUG: Bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers
Status: COMPLETED
Conditions: Thyroid Carcinoma|Thyroid Cancer|Thyroid Cancer, Follicular|Thyroid Cancer (Follicular Cell)|Thyroid Cancer, Papillary|BRAF V600E Mutation Positive
Interventions: DIAGNOSTIC_TEST: I-124 PET/CT lesion dosimetry|DRUG: Vemurafenib|DRUG: Copanlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mannitol Versus Supportive Care in Ciguatera Fish Poisoning
Status: UNKNOWN
Conditions: Ciguatoxin
Interventions: DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer|Mucositis|Pain|Radiation Toxicity
Interventions: BIOLOGICAL: palifermin|DRUG: cisplatin|OTHER: placebo|PROCEDURE: neck dissection|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Surgical Treatment Of Fulminant Clostridium Difficile Colitis
Status: TERMINATED
Conditions: Clostridium Difficile Colitis
Interventions: PROCEDURE: Ileal diversion and lavage|PROCEDURE: total abdominal colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
Status: COMPLETED
Conditions: Open|Laparoscopic|Dismembered Pyeloplasty|Primary Pelvi-Ureteric Junction|Obstruction
Interventions: PROCEDURE: Laparoscopic pyeloplasty|PROCEDURE: Open pyeloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Problem-solving Intervention for Common Adolescent Mental Health Problems in India
Status: COMPLETED
Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Interventions: BEHAVIORAL: PRIDE 'Step 1' problem-solving intervention|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of MiStent Compared to Xience in Japan
Status: UNKNOWN
Conditions: Coronary (Artery); Disease
Interventions: DEVICE: MiStent (MT005) Coronary Artery Stent|DEVICE: Xience Coronary Artery Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
Status: RECRUITING
Conditions: Platinum-resistant Ovarian Cancer|Platinum-refractory Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer|High-grade Serous Ovarian Cancer|Endometrioid Ovarian Cancer|Ovarian Clear Cell Carcinoma
Interventions: BIOLOGICAL: olvimulogene nanivacirepvec|DRUG: Platinum chemotherapy: carboplatin (preferred) or cisplatin|DRUG: Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin|DRUG: Bevacizumab (or biosimilar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Status: TERMINATED
Conditions: Vaginosis, Bacterial|Infertility|Miscarriage
Interventions: DRUG: Metronidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vegetable Oils for Use by the Snack Food Industry on Plasma Lipid Levels and Inflammatory Markers
Status: COMPLETED
Conditions: Hyperlipidemias|Metabolic Syndrome X|Cardiovascular Diseases
Interventions: BEHAVIORAL: Comparison of cooking oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men
Status: UNKNOWN
Conditions: Foreskin HIV Susceptibility
Interventions: DRUG: Oral Tinidazole|DRUG: Topical metronidazole|DRUG: Topical Clindamycin|DRUG: Topical Hydrogen Peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory
Status: COMPLETED
Conditions: Cavernous Sinus Meningioma|Pituitary Adenoma
Interventions: OTHER: Evaluation of autobiographical memory
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anticoagulation Preference by AF Patients Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: VKAs|OTHER: NOACs including Rivaroxaban (Xarelto, BAY59-7939)|OTHER: Edoxaban|OTHER: Apixaban|OTHER: Dabigatran-etexilate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Liposomal Encapsulation on Vitamin C Absorption and Metabolism
Status: RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Satge 1|DIETARY_SUPPLEMENT: Stage 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER