pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of OsrhCT in Patients With Pleurisy
Status: NOT_YET_RECRUITING
Conditions: Pleurisy
Interventions: DRUG: Recombinant Human Chymotrypsin(OsrhCT)|DRUG: Placebo for Recombinant Human Chymotrypsin(OsrhCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Infliximab in Palmoplantar Psoriasis
Status: COMPLETED
Conditions: Palmoplantar Psoriasis
Interventions: DRUG: Placebo|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Parkinson's Disease: the Globus Pallidus Internus Versus Subthalamic Nucleus
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: Subthalamic nucleus|PROCEDURE: Globus pallidus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Looks at How Food Influences the Amount of BI 1358894 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: BI 1358894|DRUG: BI 1358894 (Test)|DRUG: BI 1358894 (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Study Medicine Called Sisunatovir is Tolerated and Acts in the Bodies of Chinese Healthy Adults.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: DRUG: Sisunatovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Varenicline Versus Transdermal Nicotine Patch for Smoking Cessation in Patients With Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Varenicline|DRUG: Transdermal Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Rofecoxib Versus Naproxen in the Treatment of Chinese Patient With Rheumatoid Arthritis (0966-231)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MK0966; rofecoxib|DRUG: Comparator: naproxen tablet 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dehydroepiandrosterone Treatment for Poor Responders in In Vitro Fertilization Patients
Status: COMPLETED
Conditions: Infertility|Poor Responder to IVF Treatment
Interventions: DIETARY_SUPPLEMENT: Dehydroepiandrosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potency of Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
Status: UNKNOWN
Conditions: Adverse Effect
Interventions: DRUG: Phenylephrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind Placebo Control Study to Assess the Safety,Tolerability and Efficacy of Copaxone in Crohn's Disease
Status: UNKNOWN
Conditions: Crohns Disease
Interventions: DRUG: glatiramer acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beveled-Tip Versus(vs) Standard-Tip Vitrectomy Probe
Status: COMPLETED
Conditions: Vitrectomy
Interventions: DEVICE: Utravit High-Speed 10000 cpm Beveled Probe|DEVICE: standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inpatient Self Monitoring and Administration Study (ISMAS)
Status: UNKNOWN
Conditions: Diabetes Mellitus|Hyperglycemia|Hypoglycemia
Interventions: PROCEDURE: Self blood glucose monitoring and insulin administration|PROCEDURE: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Vitamin D, Epigallocatechin Gallate, Vitamin B6, and D-Chiro-inositol Combination on Uterine Fibroids
Status: RECRUITING
Conditions: Leiomyoma, Uterine
Interventions: DIETARY_SUPPLEMENT: Combination of Epigallocatechin gallate, vitamin D, vitamin B6, and D-Chiro-inositol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Age-related Correlates of Treatment for Late-acquired Sounds
Status: COMPLETED
Conditions: Speech Sound Disorder|Phonology Disorder|Phonology Impairment|Phonological Disorder|Articulation Disorders in Children|Developmental Phonological Disorder|Speech Disorders|Speech Delay|Articulation Disorders, Developmental
Interventions: BEHAVIORAL: articulation therapy|BEHAVIORAL: phonologic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Tesetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chios Mastiha Essential Oil on Cholesterol Levels of Healthy Volunteers
Status: COMPLETED
Conditions: Hyperlipidemias|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Chios Mastiha essential oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Response of Novel Wild Rice Enhanced Food Products (Trial 1)
Status: NOT_YET_RECRUITING
Conditions: Blood Glucose
Interventions: OTHER: White bread (control)|OTHER: Brown rice cake|OTHER: Wild rice (25%) and brown rice (75%) cake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cold Atmospheric Plasma Device Extension Study
Status: RECRUITING
Conditions: Verruca Vulgaris|Molluscum Contagiosum
Interventions: DEVICE: Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS in Elderly Depressed:Neuronavegated Study
Status: UNKNOWN
Conditions: DEPRESSION
Interventions: PROCEDURE: Transcranial Magnetic Stimulation|PROCEDURE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Model for Efficacy Prediction Cetuximab in Colorectal Cancer Liver Metastasis Patient
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer Liver Metastases
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tenecteplase Compared to Alteplase for Patients With Large Vesel Oclusion Suspicion Before Thrombectomy
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PLAYwithHEART: PLAY With Happiness, Engagement, Acceptance, and Respect With Your Team
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescents|Athletes
Interventions: BEHAVIORAL: PLAYwithHEART Programme for adolescent athletes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial To Evaluate Safety And Efficacy Of KT-301 (Formerly US-APR2020) In Subjects With Chronic Kidney Disease Stage IV
Status: RECRUITING
Conditions: Chronic Kidney Disease stage4
Interventions: DRUG: US-APR2020|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: OmnImmune®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pembrolizumab With Carboplatin and Gemcitabine in Patients With Metastatic Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma Breast Stage IV
Interventions: DRUG: Pembrolizumab|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Spirulina on Zinc, Vitamin E and Linoleic Acid Levels in Palm Skin Following Chronic Exposure to Arsenic
Status: COMPLETED
Conditions: Arsenical Keratosis
Interventions: DIETARY_SUPPLEMENT: Spirulina
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Database and Biobank of Patients With Inflammatory Myopathies: the MASC Project (Myositis, DNA, Serum, Cells) (MASC)
Status: COMPLETED
Conditions: Inflammatory Myositis|Idiopathic Inflammatory Myositis|Drug-induced Inflammatory Myositis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Focal Electrically-Administered Seizure Therapy (FEAST) Studies at Two Enrolling Sites to Further Test and Refine the Treatment
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: FEAST|DEVICE: RUL UB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Lung Diseases
Interventions: PROCEDURE: positive-pressure ventilation|PROCEDURE: extracorporeal membrane oxygenation (CO2 removal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA Guided Therapeutic Strategies for CRC Patients With Small Pulmonary Nodules
Status: RECRUITING
Conditions: Advanced Colorectal Cancer|Circulating Tumor DNA
Interventions: PROCEDURE: Local treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Imagery and Action Observation in Respiratory Training
Status: NOT_YET_RECRUITING
Conditions: Respiratory Function|Motor Imagery|Action Observation Training
Interventions: BEHAVIORAL: Motor imagery|BEHAVIORAL: Action observation|OTHER: Placebo Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Status: COMPLETED
Conditions: Morbid Obesity|Postoperative Pain|Postoperative Bowel Function|Postoperative Ambulation
Interventions: DRUG: GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE|DRUG: GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE|DRUG: GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE|DRUG: GROUP D : 0 mg MORPHINE- 0.2% LEVOBUPIVACAINE|DRUG: GROUP E : 1 mg MORPHINE-0.2 % LEVOBUPIVACAINE|DRUG: GROUP F : 2 mg MORPHINE- 0.2% LEVOBUPIVACAINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once-daily Oral Direct Factor Xa Inhibitor BAY59-7939 in Patients With Acute Symptomatic Deep-vein Thrombosis
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: Xarelto (Rivaroxaban, BAY59-7939)|DRUG: (LMW) Heparin + Vitamin K Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Telmisartan and HCTZ in Two Experimental Formulations Compared to the Standard Formulation Telmisartan and HCTZ in Healthy Female and Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan /HCTZ - compression tablet (DC)|DRUG: Telmisartan /HCTZ - dry granulation tablet (DG)|DRUG: Telmisartan /HCTZ - present commercial formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titrated Disease Management for Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Booster/ low resource|BEHAVIORAL: Booster/ low resource|BEHAVIORAL: Medium/Level 1 resource intensity|BEHAVIORAL: High/Level 2 resource intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous Sodium Thiosulfate on Coronary Calcification in Patients on Hemodialysis
Status: COMPLETED
Conditions: Coronary Calcification|Vascular Calcification
Interventions: DRUG: 25% intravenous (IV) sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Milk Ingredients on Glucose Regulation and Inflammation
Status: COMPLETED
Conditions: Glucose Regulation|Low-grade Inflammation
Interventions: OTHER: nutrient-enriched milk|OTHER: regular milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 in Subjects With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson Disease
Interventions: DRUG: PF-06649751|DRUG: Trimethobenzamide Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Research on the Intervention of VR-based Emotion Regulation Technology on Adolescent Non-suicide Self-injury Behavior
Status: RECRUITING
Conditions: Non-suicidal Self-injury
Interventions: DEVICE: Virtual Reality Technology|OTHER: Routine mental health course training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Symptomatic Knee Osteoarthritis
Interventions: OTHER: partial blood flow restriction (PBFR)|OTHER: low intensity resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Rapid Steroid Withdrawal on Subclinical Markers of Rejection
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus|DRUG: mycophenolate mofetil|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PRS-080
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PRS-080#022-DP|DRUG: PRS-080-Placebo#001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effects of Mixed Spices on Cardiometabolic Function - the PolySPice (PSP) Study
Status: COMPLETED
Conditions: Cardiometabolic Risk
Interventions: OTHER: Rice with tomatoes and peeled aubergine (no spice)|OTHER: Rice with vegetables and low spice|OTHER: Rice with vegetables and high spice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy.
Status: UNKNOWN
Conditions: Attention-deficit/Hyperactivity Disorder|Autonomic Nervous System Imbalance|Obstructive Sleep Apnea of Child
Interventions: BEHAVIORAL: Sleep and healthy lifestyle education|OTHER: Other supportive care|PROCEDURE: Adenotonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Periodontitis With Er:YAG Laser
Status: COMPLETED
Conditions: Generalized Moderate Chronic Periodontitis|Generalized Severe Chronic Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: Scaling and root planing|DEVICE: Er:YAG Laser|DEVICE: Hand instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesio Taping on Hip Abductor Muscle Strength and EMG Activity
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: OTHER: Kinesio Tape|OTHER: Micropore Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: carboplatin|DRUG: fluorouracil|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Effects of Nateglinide vs. Glibenclamide on Renal Hemodynamics and Albumin Excretion
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: nateglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BowelScope: Accuracy of Detection Using ENdocuff Optimisation of Mucosal Abnormalities
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colonic Polyp|Adenoma|Neoplasia GI|Digestive System Neoplasms|Intestinal Neoplasms|Neoplasms, Glandular and Epithelial|Digestive Disease|Intestinal Diseases|Colonic Diseases|Rectal Diseases|Intestinal Polyps|Polyps|Pathological Conditions, Anatomical
Interventions: DEVICE: Endocuff Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ohio Patient Navigator Research Program
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer|Colon Cancer|Rectal Cancer|Abnormal Breast Cancer Screening Tests|Abnormal Cervical Cancer Screening Tests|Abnormal Colon Cancer Screening Tests
Interventions: BEHAVIORAL: Patient Navigator matched with subject|BEHAVIORAL: Subjects are mailed informational/educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chemotherapy Intensification in Patients With High Lactate Dehydrogenase Values and Soluble Syndecan1 Levels
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOXIRI|DRUG: FOLFOX|DRUG: FOLFIRI|DRUG: Bevacizumab|DRUG: LV5FU2|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy to Patients With CA19-9-elevated Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine, Nab-paclitaxel, Irinotecan|RADIATION: Intensity-Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentriox - Induction of Oxidative Stress
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DRUG: Penicillin V|DRUG: Trimethoprim|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Feasibility of the Application of Thoracic Puncture Tube After Pulmonary Lobectomy
Status: UNKNOWN
Conditions: Chest Tubes|Pneumonectomy|Minimally Invasive Surgery
Interventions: PROCEDURE: thoracic drainage management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Simplification Study of Unboosted Reyataz With Epzicom (ASSURE)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Reyataz + Norvir + Truvada|DRUG: Reyataz + Epzicom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmicort Respules(Budesonide Inhalation Suspension) vs Singulair, Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide inhalation suspension|DRUG: Montelukast Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab, Docetaxel, Cisplatin, Radiation Therapy, and Surgery in Treating Patients With Newly Diagnosed, Locally Advanced Esophageal Cancer or Cancer of the Gastroesophageal Junction
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: cisplatin|DRUG: docetaxel|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Paliperidone Palmitate in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone IR (Period 1)|DRUG: Paliperidone palmitate F015 (Panel A: treatment group 1)|DRUG: Paliperidone palmitate F015 (Panel A: treatment group 2)|DRUG: Paliperidone palmitate F015 (Panel B: treatment group 1)|DRUG: Paliperidone palmitate F015 (Panel B: treatment group 2)|DRUG: Paliperidone palmitate F015 (Panel B: treatment group 3)|DRUG: Paliperidone palmitate F015 (Panel B: treatment group 4)|DRUG: Paliperidone palmitate F015 (Panel B: treatment group 5)|DRUG: Paliperidone palmitate F016|DRUG: Paliperidone palmitate F015 (Panel D: treatment group 1)|DRUG: Paliperidone palmitate F015 (Panel D: treatment group 2)|DRUG: Paliperidone palmitate F015 (Panel D: treatment group 3)|DRUG: Paliperidone palmitate F015 (Panel D: treatment group 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Observational, Multicenter Study of Patients Following Initiation of a New Course of Treatment for Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Urinary Bladder Overactive|Overactive Bladder|Urinary Bladder Diseases|Urologic Diseases
Interventions: DRUG: mirabegron|DRUG: antimuscarinic medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pegylated Arginine Deiminase in Treating Patients With Metastatic Melanoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: ADI-PEG-20|OTHER: Pharmacology Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Coronary Artery Bypass|Aortic Aneurysm|Valve Surgery|Kidney Diseases
Interventions: DRUG: AP214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effect of Antibiotics on the Microbiology of the Bladder in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Urogynaecology
Interventions: OTHER: None - this is a prospective observational study. Patients will be prescribed their usual treatment (antibiotics) and the effect on urine studied
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Raisins Versus Alternative Snacks on Cardiovascular Risk Factors In Generally Healthy Subjects
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: OTHER: Alternative Snack Comparator|OTHER: Raisins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of HRS9531 Injection in Type 2 Diabetes Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: HRS9531 injection|DRUG: HRS9531 injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Elonva in Combination With Hp-FSH Versus Elonva With Low Dose hCG
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: low dose hCG|DRUG: hp-FSH|DRUG: Corifollitropin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Polyphenolic Beverage in Healthy Volunteers
Status: WITHDRAWN
Conditions: Healthy|Safety Issues
Interventions: OTHER: Polyphenolic beverage from extract of Vachellia farnesiana|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers
Status: TERMINATED
Conditions: Gastrointestinal Cancer|Colorectal Cancer|Pancreatic Adenocarcinoma|Gastric Cancer|Esophageal Cancer|Cholangiocarcinoma|Hepatocellular Carcinoma|Neuroendocrine Tumors|GIST, Malignant
Interventions: BEHAVIORAL: Serious Illness Conversation Guide (SICG)|BEHAVIORAL: Quality of Life (QOL) survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: BIOLOGICAL: H5N1 (6-2) AA ca Recombinant (A/VietNam/1203/2004 x A/AnnArbor/6/60/ca)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Dabrafenib in Combination With Trametinib as Adjuvant Treatment for Chinese Patients With Stage III BRAF V600 Mutation-positive Melanoma After Complete Resection
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: dabrafenib|DRUG: trametinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy
Status: RECRUITING
Conditions: Epilepsy
Interventions: DIAGNOSTIC_TEST: StiMiC stimulation condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Swabbing of Subcutaneous Tissues of Cesarean Section Wounds With Povidone Iodine
Status: UNKNOWN
Conditions: Wound Infection
Interventions: DRUG: Povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP300 and HIV-1 SF-2 rgp120 in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV MN120TMGNP (vCP300)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: BEHAVIORAL: Cigarette flavor restricted and e-cigarette flavor restricted|BEHAVIORAL: Cigarette flavor restricted and e-cigarette flavor unrestricted|BEHAVIORAL: Cigarette flavor unrestricted and e-cigarette flavor restricted|BEHAVIORAL: Cigarette flavor unrestricted and e-cigarette flavor unrestricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implant/Abutment Module Stability of Original vs Compatible Connections
Status: UNKNOWN
Conditions: Bone Loss, Alveolar|Dental Implant Failure Nos
Interventions: DEVICE: Original CAD/CAM prosthetic abutment|DEVICE: Compatible CAD/CAM abutment|PROCEDURE: Local anesthesia|DRUG: Painkillers|DRUG: Mouthwashes|DEVICE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study Of Axitinib In Combination With Crizotinib In Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: axitinib|DRUG: crizotinib|DRUG: axitinib|DRUG: crizotinib|DRUG: axitinib|DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Fulvestrant in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Aromatase Inhibitor Therapy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: fulvestrant|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive Compulsive Disorder|Body Dysmorphic Disorder|Tourette Syndrome|Trichotillomania|Panic Disorder|Social Phobia|Generalized Anxiety Disorder|Depression|Post-Traumatic Stress Disorder|Attention Deficit Hyperactivity Disorder|Eating Disorder|Specific Phobia|General Medical Condition
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness
Status: COMPLETED
Conditions: Hypotension|Shock|Fluid Challenge|Fluid Responsiveness
Interventions: OTHER: fluid challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Manual Therapy With Directed Vestibular Rehabilitation in Patients With Unilateral Peripheral Vestibular Hypofunction.
Status: COMPLETED
Conditions: Peripheral Vestibular Disorder
Interventions: OTHER: Manual therapy and vestibular rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Bevacizumab|DRUG: Capecitabine|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: risperidone oral solution|DRUG: haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Linagliptin + metformin|DRUG: Linagliptin+metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intensive Perioperative Nutrition Therapy Among Adults Undergoing Gastrointestinal & Oncology Surgery
Status: UNKNOWN
Conditions: Perioperative Complication
Interventions: DIETARY_SUPPLEMENT: Oral Nutrition Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Web Platform for EmPOWERment in Early Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: EBBC programme|BEHAVIORAL: Control group programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immune Modulation Therapy for Pompe Disease
Status: UNKNOWN
Conditions: Pompe Disease
Interventions: DRUG: Rituximab|DRUG: intravenous immune globulin|DRUG: Bortezomib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temperature Monitoring With InnerSense Esophageal Temperature Sensor/Feeding Tube After Birth Through Stabilization in VLBW Infants
Status: COMPLETED
Conditions: Body Temperature
Interventions: DEVICE: Philips InnerSense Esophageal Temperature Sensor/Feeding Tube|DEVICE: Standard of care feeding tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CRP on Radiobiological and Clinical Studies on Viral-Induced Cancer's Response to Radiotherapy
Status: COMPLETED
Conditions: Cervix Cancer
Interventions: RADIATION: Radiotherapy|RADIATION: Radiotherapy|RADIATION: Radiotherapy/Cisplatin|RADIATION: Radiotherapy/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Nano Silver Fluoride Versus Calcium Hydroxide in Indirect Pulp Treatment
Status: COMPLETED
Conditions: Deep Caries
Interventions: DRUG: Nano Silver Fluoride|DRUG: Calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine for Epileptic Encephalopathy
Status: COMPLETED
Conditions: Epileptic Encephalopathy, Childhood-Onset
Interventions: DRUG: Memantine Hydrochloride 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Bacteria in Prevention of the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Lactobacillus plantarum PCS 26|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vdrive Evaluation of Remote Steering and Testing in Lasso Electrophysiology Procedures Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Vdrive Lasso navigation|PROCEDURE: Manual Lasso navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine GSK2186877A in Adults 65 Year of Age and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Bio's influenza vaccine GSK2186877A|BIOLOGICAL: Fluarix TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
Status: NOT_YET_RECRUITING
Conditions: Sedation|Emergence Delirium
Interventions: DRUG: Nebulization of dexmedetomidine and ketamine|DRUG: Nebulization of dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With PD or AD and in Healthy Subjects
Status: TERMINATED
Conditions: Parkinson Disease|Alzheimer Disease|Healthy Controls|Multiple Sclerosis
Interventions: DRUG: [123I]CLINDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Effectiveness of IIMR Versus CDSMP
Status: RECRUITING
Conditions: Mental Illness|Chronic Disease
Interventions: BEHAVIORAL: Integrated Illness Management and Recovery|BEHAVIORAL: Chronic Disease Self-Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Acute Exercise on Endothelial Function in Patients With Type 1 Diabetes.
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: Resistance exercise session|BEHAVIORAL: Aerobic exercise session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Open Angle Glaucoma (POAG)|Primary Open Angle Glaucoma of Both Eyes|Primary Open-Angle Glaucoma, Unspecified Eye|Ocular Hypertension (OHT)
Interventions: DRUG: Experimental: QLS-111 ophthalmic solution, (0.015%)|DRUG: Experimental: QLS-111 ophthalmic solution, (0.03%)|DRUG: Experimental: QLS-111 ophthalmic solution, (0.075%)|OTHER: QLS-111 ophthalmic vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Thoraflex™ Hybrid Device for the Treatment of Aneurysm/Dissection of the Descending Thoracic Aorta
Status: UNKNOWN
Conditions: Aortic Arch; Aneurysm, Dissecting
Interventions: DEVICE: Thoraflex™ Hybrid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accessible and Affordable Moisturizers for Atopic Eczema
Status: COMPLETED
Conditions: Childhood Atopic Dermatitis
Interventions: OTHER: Baby oil|OTHER: petroleum jelly|OTHER: Glycerine:petroleum jelly 2:1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparison of Teicoplanin and Vancomycin in Initial Empirical Antibiotic Regimen for Febrile Neutropenic Patients
Status: COMPLETED
Conditions: Infection|Febrile Neutropenia
Interventions: DRUG: Teicoplanin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral OKT3 in Combination With Beta-D-Glucosylceramide
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: OKT3|DRUG: OKT3, GC|DRUG: OKT3|DRUG: OKT3, GC|DRUG: OKT3|DRUG: GC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cosmesis and Body Image After Single Port or 4-Port Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Symptomatic Gallstone Disease
Interventions: DEVICE: Single Port Cholecystectomy|DEVICE: 4 Port Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zone 2 Flexor Tendon Repair With CoNextions TR Implant System
Status: UNKNOWN
Conditions: Tendon Injury - Hand
Interventions: PROCEDURE: Operative repair of Zone 2 FDP tendon lacerations|DEVICE: CoNextions TR Implant System|DEVICE: 4-strand locked cruciate repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Docetaxel + ARN-509 in Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide Acetate|DRUG: Prednisone|DRUG: Docetaxel|DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm, Thoracic|Penetrating Ulcer
Interventions: DEVICE: RelayPro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib and Erlotinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: celecoxib|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Operative (partial arthroscopy)|PROCEDURE: Conservative (diagnostic arthroscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LY3200882 and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615)
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: LY3200882
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate in Treating Patients With Liver Cancer That Can Be Removed by Surgery
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Depression|Anxiety
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study for Implantation and Retrieval Procedures Using the VENATECH® Retrieval Filter System
Status: COMPLETED
Conditions: Pulmonary Thrombo-embolism
Interventions: DEVICE: VenaTech® (VenaTech Retrievable Filter)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of Vardenafil in Subjects With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Capecitabine, and Bevacizumab Followed By Surgery and/or Radiofrequency Ablation in Patients With Colorectal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: oxaliplatin|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inter-relationship Between Vitamin D Requirements and Calcium Intake in Older Adults
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (20 micrograms/day)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION