pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: AZD6244|DRUG: docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures.
Status: COMPLETED
Conditions: Epilepsy
Interventions: OTHER: Placebo|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction of SHR3680 With Repaglinide and Bupropion
Status: UNKNOWN
Conditions: Prostate Cancer Patients
Interventions: DRUG: Repaglinide, Bupropion and SHR3680
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylactic Anticoagulation for Catheter-related Thrombosis
Status: UNKNOWN
Conditions: Venous Thrombosis Due to Central Venous Access Device (Disorder)|Prophylactic Anticoagulation|Patients With Tumor
Interventions: DRUG: Rivaroxaban 10mg|DRUG: Aspirin 100mg|DRUG: low molecule heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Imatinib in Patients With Desmoid Tumor and Chondrosarcoma
Status: COMPLETED
Conditions: Advanced Desmoid Tumor|Advanced Chondrosarcoma
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Erlotinib With Docetaxel in Selected Non Small Cell Lung Cancer Patients in First Line Treatment
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Perioperative Hemodynamic Goal-directed Therapy in Major Abdominal Surgery (iPEGASUS-trial)
Status: COMPLETED
Conditions: Hemodynamic Instability|Cardiac Output, High|Peroperative Complication
Interventions: PROCEDURE: Individualized Goal Directed Therapy|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Anti-Influenza Virus Monoclonal Antibody to Treat Influenza
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: TCN-032|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Pudendal Nerve Block in Children: A Descriptive Study of Feasibility
Status: COMPLETED
Conditions: Pudendal Nerve Block
Interventions: PROCEDURE: Ultrasound guided transperineal pudendal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lunch Cancer
Interventions: DRUG: Buparlisib|DRUG: Buparlisib placebo|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TAK-925 in Participants With Obstructive Sleep Apnea (OSA) Who Are Experiencing Excessive Daytime Sleepiness (EDS) Despite Adequate Use of Continuous Positive Airway Pressure (CPAP)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: TAK-925|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Potassium Supplement|DRUG: Furosemide 20 MG|DEVICE: Compression Garment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Beta-Glucan in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: beta-glucan MM-10-001|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Simiaowan in Prevention of Acute Flares in Chronic Gout Patients Initiating Febuxostat Therapy
Status: UNKNOWN
Conditions: Gout Flare
Interventions: DRUG: simiaowan|DRUG: placebo|DRUG: febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Potential Influence of Esomeprazole on the Pharmacokinetics of Pritelivir
Status: COMPLETED
Conditions: HSV Infection
Interventions: DRUG: Pritelivir|DRUG: ESO and pritelivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or Vulva
Status: TERMINATED
Conditions: Cervical Cancer Stage IV|Vulvar Cancer, Stage IV
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-label, Multicenter, Safety and Pharmacokinetic Study of EDI200
Status: COMPLETED
Conditions: X-linked Hypohidrotic Ectodermal Dysplasia
Interventions: DRUG: EDI200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACL Reconstruction With/Without ALL Reconstruction
Status: RECRUITING
Conditions: ACL Injury|ALL
Interventions: PROCEDURE: ACL reconstruction|OTHER: ALL anatomic|OTHER: ALL tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Community - Based Cross-sector Network for the Management of Mental Health Problems and Disorders Associated With Forced Displacement Due to Armed Conflict in the Municipality of Soacha - Cundinamarca
Status: COMPLETED
Conditions: Mental Disorder|Mental Disorder in Adolescence|Mental Problems|Mental Disorder in Infancy
Interventions: OTHER: Community intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Systemic Biomarkers of Brain Injury From Hyperammonemia
Status: RECRUITING
Conditions: Urea Cycle Disorder|Organic Acidemia|Maple Syrup Urine Disease|Glutaric Acidemia I|Fatty Acid Oxidation Disorder|Hypoxic-Ischemic Encephalopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Motor Imagery and Action Observation on Upper Limb Motor Chances and Cognitive Chances in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Motor Imagery|OTHER: Action Observation|OTHER: Exoskeletons|OTHER: Execution of the Action
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Daily Supplementation of Nutriose® on the Fecal Microbiota in Volunteers.
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DIETARY_SUPPLEMENT: NUTRIOSE®|DIETARY_SUPPLEMENT: GLUCIDEX® IT21 (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Lamaline® , 3 different doses, Dafalgan codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cirrhosis
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Defined Green Tea Catechin Extract|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|OTHER: Pharmacological Study|OTHER: Questionnaire Administration|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Blood Transfusions and Immune Response
Status: COMPLETED
Conditions: Infection After Transfusion|Transfusion-related Immunomodulation Reaction|Cytokine Storm|Surgery
Interventions: PROCEDURE: restrictive transfusion strategy|PROCEDURE: liberal transfusion strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Demonstrate the Relative Bioavailability of Atenolol Tablets, 100 mg
Status: COMPLETED
Conditions: Angina|Hypertension
Interventions: DRUG: Atenolol (Tenormin) 100 mg Tablets Zeneca (Astra Zeneca Pharmaceutical)|DRUG: Atenolol 100 mg Tablets (Geneva Pharmaceutical, Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Immunogenicity of Inactivated Poliomyelitis Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Sabin strain)|BIOLOGICAL: Inactivated Poliomyelitis Vaccine (Salk strain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males
Status: COMPLETED
Conditions: Anal Cancer|Nonneoplastic Condition|Penile Cancer|Precancerous Condition
Interventions: BIOLOGICAL: quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness-Based Stress-Reduction in Patients With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease Colon
Interventions: BEHAVIORAL: Cognitive behavioral mindfulness intervention|BEHAVIORAL: Cognitive behavioral mindfulness intervention after 3-month wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Versus Fentanyl for Surgical Abortions
Status: COMPLETED
Conditions: Abortion in First Trimester|Pain, Procedural|Opioid Use
Interventions: DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Surgical Versus Catheter Ablation Approaches for Primary Treatment of Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation, Persistent
Interventions: PROCEDURE: Thoracoscopic pulmonary vein isolation without additional lesion + left atrial appendage exclusion/amputation|PROCEDURE: Catheter pulmonary vein isolation without additional lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Temporal Epilepsy Neuropsychological Assessment of Faces
Status: UNKNOWN
Conditions: Anterior Temporal Epilepsy|Anterior Temporal Lobectomy|Face Perception
Interventions: OTHER: Mooney test|OTHER: Benton Face Recognition test|OTHER: Face inversion effect test|OTHER: Face composite effect test|OTHER: Cambridge Face Memory Test|OTHER: Matching different view test|OTHER: Memorizing and recognition of new faces test|OTHER: Memorizing and recognition of new objects test|OTHER: Recognition of celebrities and access to semantic information test|PROCEDURE: Lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electroacupuncture Modulates SPMs Metabolism and Respiratory Symptoms in Patients With Sepsis Complicating ARDS
Status: RECRUITING
Conditions: Sepsis|Acute Respiratory Distress Syndrome
Interventions: DEVICE: electroacupuncture treatment|DEVICE: sham electroacupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase II Avastin + Bortezomib for Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Avastin|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Chest Wall Mechanics on Lung and Cardiovascular Function During Delayed Sternal Closure
Status: ACTIVE_NOT_RECRUITING
Conditions: Palliation of Congenital Heart Diseases|Cardiopulmonary Bypass|Chest Wall Mechanics|Neonatal Delayed Sternal Closure
Interventions: OTHER: Esophageal manometry catheter at various PEEP levels and tidal volumes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users
Status: COMPLETED
Conditions: Drug Abuse
Interventions: DRUG: Intravenous placebo|DRUG: Intranasal placebo|DRUG: Intravenous racemic ketamine|DRUG: Esketamine 112 mg|DRUG: Esketamine 84 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)
Status: COMPLETED
Conditions: Head and Neck Cancer|Squamous Cell Cancer
Interventions: DRUG: Afatinib, Ribavirin, and weekly carboplatin/paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Supine Thoracic Spine Manipulation|OTHER: Prone Thoracic Spine Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Chronic Polyethyleneglycol3350 Use in Constipated Patients
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: polyethyleneglycol3350
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delivra Topical Creatine for Improving Muscular Power
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: Delivra TM Livsport preworkout cream|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma
Status: UNKNOWN
Conditions: Carcinoma of the Anal Canal
Interventions: RADIATION: Pencil Beam scanning Radiation|DRUG: 5-fluorouracil|DRUG: Mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PercutaneOus StEm Cell Injection Delivery Effects On Neomyogenesis in Dilated CardioMyopathy (The POSEIDON-DCM Study)
Status: COMPLETED
Conditions: Non-ischemic Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Autologous hMSCs|BIOLOGICAL: Allogeneic hMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of YRA-1909 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: YRA-1909 low dose|DRUG: YRA-1909 mid dose|DRUG: YRA-1909 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Autologous Platelet-rich Plasma in Uterine Wound Healing
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: autologus platelet rich plasma|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Functional Result of the Reinsertion of the Subscapular in Reverse Shoulder Prostheses According to the Healing of the Subscapular
Status: RECRUITING
Conditions: Reverse Shoulder Prothesis|Healing of the Subscapularis
Interventions: PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study Comparing D961H Sachet and D961H Capsule in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Bioequivalence Study
Interventions: DRUG: D961H Sachet 20 mg|DRUG: D961H HPMC capsule 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Test if TV-46000 is Safe for Maintenance Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: TV-46000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open, Non-Comparative Study To Evaluate The Performance Of The Medical Device JANESSE®
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: Janesse® is a sterile, injectable, non-pyrogenic, re-absorbable medical product made of reticulated hyaluronic acid of non-animal origin, produced via bacterial fermentation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Resectable Osteosarcoma Treated by Metastasectomy and Pre-operative Immunotherapy and Stereotactic Body Radiotherapy (PROMIS): a Prospective Clinical Trial
Status: RECRUITING
Conditions: Osteosarcoma
Interventions: COMBINATION_PRODUCT: metastasectomy and pre-operative immunotherapy (gemcitabine and penpulimab ) and stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison of Diagnostic Accuracy Between Contrast-enhanced Harmonic and Conventional EUS-guided Fine-needle Biopsy in Solid Pancreatic Lesions
Status: COMPLETED
Conditions: Pancreatic Solid Lesions
Interventions: PROCEDURE: Endoscopic ultrasound-guided fine needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, Pharmacokinetics (PK), and Primary Clinical Efficacy of LY01616 in Patients With Advanced Solid Tumors
Status: ENROLLING_BY_INVITATION
Conditions: Advanced Solid Tumors
Interventions: DRUG: LY010616
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study
Status: COMPLETED
Conditions: Rolandic Epilepsy|Nocturnal Frontal Lobe Epilepsy|Landau-Kleffner Syndrome|Electrical Status Epilepticus During Slow Wave Sleep
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain-Centered Therapy Versus Medication for Urgency Urinary Incontinence : Hypnotherapy Or Pharmacotherapy
Status: COMPLETED
Conditions: Urinary Incontinence, Urge
Interventions: DRUG: Anticholinergic medications|BEHAVIORAL: Hypnotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE Oasys 1-Day|DEVICE: Precision 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment of Venous Leg Ulcers.
Status: RECRUITING
Conditions: Venous Leg Ulcers (VLU)
Interventions: DRUG: ON101 Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Org 25935 Versus Placebo as Augmentation to Cognitive-behavioral Therapy to Treat Panic Disorder (P05705)
Status: TERMINATED
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|DRUG: Org 25935|DRUG: Org 25935|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complaints Associated With Use of Pre-Filled Pen B With Type 2 Diabetics on Twice-Daily Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: insulin lispro injection [rDNA origin] Low Mix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Ramosetron on Heart Rate-corrected QT Interval During Robot-assisted Laparoscopic Prostatectomy With Steep Trendelenburg Position
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ramosetron|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TNFα Monoclonal Antibody for Acute Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: DRUG: TNFα Monoclonal Antibody|DRUG: Methylprednisolone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of REGN1193 in Patients With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: REGN1193|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority Trial to Assess the Safety and Performance of the Evolution Coronary Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PROMUS(TM) Element (TM) Stent System|DEVICE: Evolution Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Application Techniques for LET Gel
Status: COMPLETED
Conditions: Lacerations|Pain, Procedural|LET
Interventions: DRUG: LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MBCT-T for Preoperative Pain Catastrophizing and Pain Outcomes After Spine Surgery
Status: RECRUITING
Conditions: Pain
Interventions: BEHAVIORAL: Telephone-Delivered Mindfulness-based Cognitive Therapy (MBCT-T)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability and Efficacy of GSK2330811 in Crohn's Disease
Status: WITHDRAWN
Conditions: Crohns Disease|Crohn's Disease
Interventions: DRUG: GSK2330811|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Dosing for Total Joint Arthroplasty
Status: COMPLETED
Conditions: Arthropathy of Hip|Arthropathy of Knee
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Sitravatinib as Consolidation Treatment Following Concurrent Chemoradiation in Patients With Locally Advanced, Unresectable NSCLC
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Sitravatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics (L. Helveticus, B. Longum, and B. Bifidum) on Immune Function and Digestive Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic- Bifidobacterium Bifidum|DIETARY_SUPPLEMENT: Sugar Pill|DIETARY_SUPPLEMENT: Probiotic- Lactobacillus helveticus|DIETARY_SUPPLEMENT: Probiotic- Bifidobacterium longum ss. Infantis R0033
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extracolonic Findings on Computed Tomography (CT) Colonography
Status: UNKNOWN
Conditions: Solitary Pulmonary Nodules|Multiple Pulmonary Nodules|Renal Neoplasms|Adrenal Gland Neoplasms|Aortic Aneurysm, Abdominal|Liver Neoplasms|Adnexal and Skin Appendage Neoplasms|Lymphadenopathy|Pancreatic Neoplasms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
Status: RECRUITING
Conditions: Peripheral Nerve Injury
Interventions: DRUG: Polyethylene glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Suspicion of Hypoglycemic Effect of mRNA Based Covid-19 Vaccines (Polyethylene Glycol) Will Happen , Observational Study on Diabetic Patients at Saudia Arabia
Status: UNKNOWN
Conditions: Diabetic Complication|Covid19 Virus Infection|Hypoglycemia|Polyethylene Glycol Adverse Reaction
Interventions: BIOLOGICAL: polyethelyene glycol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Methacholine Bronchial Provocation With Wright and Devilbiss646 Nebulizers
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: methacholine|DEVICE: Wright Nebulizer|DEVICE: Devilbiss646 Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Detection of At-risk Septic Patients
Status: RECRUITING
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: Measuring tissue oxygenation|DIAGNOSTIC_TEST: Procalcitonin|DIAGNOSTIC_TEST: Mid-regional proadrenomedullin|DIAGNOSTIC_TEST: Hand-held video microscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lazertinib in Patients With NSCLC With Asymptomatic or Mild Symptomatic Brain Metastases After Failure of EGFR TKI.
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: DRUG: lazertinib(YH25448)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-hospital Diabetes Management With Flash Glucose Monitoring (isCGM) - the INDIGO Study, Part B
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus|Diabetes Mellitus
Interventions: OTHER: isCGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: An Open-Label Study to Evaluate the Efficacy of High-Dose Gammaplex in Children on the Autism Spectrum
Status: UNKNOWN
Conditions: Autism|Autistic Disorder|Asperger's Disorder|PDD|Pervasive Developmental Disorder
Interventions: DRUG: Gammaplex 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multitarget tDCS for Neuropathic Pain
Status: NOT_YET_RECRUITING
Conditions: Neuropathic Pain
Interventions: DEVICE: Mutitarget tDCS|DEVICE: Single-target tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: DEVICE: screws-internal fixation|DEVICE: TARGON FN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Gastrinoma|Glucagonoma|Insulinoma|Metastatic Gastrointestinal Carcinoid Tumor|Pancreatic Polypeptide Tumor|Pulmonary Carcinoid Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma|Somatostatinoma
Interventions: DRUG: regorafenib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac MRI in Measuring the Impact of Anti-androgen Treatment on Cardiac Function in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Injury|Prostate Carcinoma
Interventions: PROCEDURE: Magnetic Resonance Imaging|BEHAVIORAL: Exercise Intervention|PROCEDURE: Perfusion Magnetic Resonance Imaging|BEHAVIORAL: Exercise Intervention|PROCEDURE: Spectroscopy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Episodic Future Thinking and Weight-Loss
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Episodic Future Thinking Group|BEHAVIORAL: Healthy Thinking Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tegio Consolidation Therapy for NPC Patients With High Risk of Metastasis
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Tegafur-Gimeracil-Oteracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of ARRY-502 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ARRY-502|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DRUG: ELND005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HFNC vs NIPPV Following Extubation
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: High Flow Nasal Canula following extubation|PROCEDURE: Non-Invasive Positive Pressure Ventilation following extubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-linked and Non-cross-linked Hyaluronic Acid in Subdeltoid Bursitis
Status: NOT_YET_RECRUITING
Conditions: Subdeltoid Bursitis|Hyaluronic Acid
Interventions: DRUG: cross-linked hyaluronic acid|DRUG: non-cross-linked hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vamikibart in Participants With Uveitic Macular Edema
Status: RECRUITING
Conditions: Uveitic Macular Edema
Interventions: DRUG: Vamikibart|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid Nutritional Supplement on Malnutrition Hospitalized Patient
Status: UNKNOWN
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Liquid Nutritional Supplement from Hospital Product|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Trivalent Split Virion Influenza Vaccine Fluviral™ (2013-2014 Season) in Adults Aged 18 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluviral™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Weekly Paclitaxel With Ramucirumab in Participants With Advanced Gastric Adenocarcinomas
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: BIOLOGICAL: Ramucirumab (IMC-1121B )|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Cycling FES and Conservative Rehabilitation Therapy on Stroke Patients
Status: COMPLETED
Conditions: Hemiplegia
Interventions: OTHER: Conservative rehabilitation|OTHER: Cycling Functional Electrical Stimulation in addition to Conservative Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men
Status: COMPLETED
Conditions: Sterility, Reproductive
Interventions: BIOLOGICAL: Human kisspeptin-10 (metastin 45-54)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Protein Bioavailability of Wolffia Globosa (Mankai); Acute Test Meal Effects
Status: COMPLETED
Conditions: Men With Mild Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: White cheese|DIETARY_SUPPLEMENT: Green peas|DIETARY_SUPPLEMENT: Mankai
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Eye Movement Desensitisation and Reprocessing (EMDR) to Improve Mental Health Following Intensive Care Admission
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Critical Illness|Eye Movement Desensitisation and Reprocessing|Depression, Anxiety
Interventions: BEHAVIORAL: Eye Movement Desensitisation and Reprocessing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Tenapanor|DRUG: Placebo|DRUG: Sevelamer Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Handled Echocardiography and Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: OTHER: handled echocardiography in home monitoring program|OTHER: ecg and clinical evaluation in home monitoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: BMS-986322|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Methods on Resistant Sites in Stable Vitiligo Patients
Status: UNKNOWN
Conditions: Vitiligo
Interventions: PROCEDURE: SUCTION BLISTER EPIDERMAL GRAFTING|PROCEDURE: MINI PUNCH GRAFTING|PROCEDURE: NON CULTURED EPIDERMAL CELL SUSPENSION
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nordic Study on the Effects of Growth Hormone (Norditropin SimpleXx) Treatment in Adults With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Norditropin SimpleXx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Translational Trial on Molecular Markers and Functional Imaging to Predict Response of Preoperative Treatment of Breast Cancer Early
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Docetaxel|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carnosine Supplementation on Quantity/Quality of Oral Salivae.
Status: UNKNOWN
Conditions: Oral Diseases
Interventions: DIETARY_SUPPLEMENT: 400 mg mucoadhesive oral tablet|DIETARY_SUPPLEMENT: placebo mucoadhesive oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase Inhibitors
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission|Minimal Residual Disease|Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Interventions: DRUG: Dasatinib|DRUG: Imatinib Mesylate|DRUG: Nilotinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Over S1 Enhance Motor Learning in Healthy People
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Motor Learning
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation over primary somatosensory cortex|DEVICE: repetitive Transcranial Magnetic Stimulation over primary motor cortex|DEVICE: sham repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of the 1-minute Sit-to-stand Test in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: 1-minute sit-to-stand test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Influence of Manual and Verbal Guidance for Therapeutic Results in People With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: Virtual Reality with Manual and Verbal Guidance|OTHER: Virtual Reality with No Manual and Verbal Guidance|OTHER: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maribavir vs. Valganciclovir for CMV Prophylaxis in High-Risk Kidney Transplant Recipients
Status: RECRUITING
Conditions: Transplant Complication|CMV
Interventions: DRUG: Maribavir|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patients
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SDF Application in Oral Cancer Patients to Prevent Dental Caries
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DEVICE: silver diamine fluoride, 38%|DEVICE: Sodium fluoride gel, 5000 PPM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gojiberry Intake (Lycium Barbarium) on Macular Function
Status: COMPLETED
Conditions: Macular Pigment Optical Density
Interventions: DIETARY_SUPPLEMENT: Goji berry|DIETARY_SUPPLEMENT: Lutein + zeaxanthin supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Crofelemer to Treat Diarrhea Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Colonic Diseases|Diarrhea|Gastrointestinal Disease
Interventions: DRUG: crofelemer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone Variation on the Final Day of Oocyte Maturation.
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation|Progesterone Variation on Trigger Day|Circadian Rhythm|Oocyte Donors
Interventions: DIAGNOSTIC_TEST: Serum progesterone measure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
Status: RECRUITING
Conditions: Multiple Sclerosis|Gait Disorders, Neurologic|Motility Disorder|Cognitive Impairment
Interventions: DEVICE: Robotic Exoskeleton Rehabilitation|OTHER: Conventional Gait Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon
Status: UNKNOWN
Conditions: Atrial Fibrillation|Left Atrial Thrombosis
Interventions: DRUG: Dabigatranetexilate|DRUG: Phenprocoumon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOBILE Intervention in College Students With Elevated Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Intervention group was asked to take their BP daily and rate their motivation level and communicate with the research assistant. Their level will trigger the appropriate behavioral change SMS prompt.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Uveal Melanoma
Interventions: DEVICE: Novocure Optune|DRUG: Opdivo|DRUG: Yervoy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mollii - Personalized Suit for Treatment of Spasticity, GFMCS 3-5
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: DEVICE: TENS incorporated into the Mollii suit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )
Status: UNKNOWN
Conditions: Death, Sudden, Cardiac|Out-Of-Hospital Cardiac Arrest|Ventricular Fibrillation|Cardiopulmonary Arrest With Successful Resuscitation
Interventions: PROCEDURE: ECMO resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JET-GBS - Japanese Eculizumab Trial for GBS
Status: COMPLETED
Conditions: Gullain Barre Syndrome
Interventions: DRUG: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Lapatinib in Combination With Sorafenib in Patients With Advanced Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Lapatinib and Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT