pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: 7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Acute Promyelocytic Leukemia (M3)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Blastic Phase Chronic Myelogenous Leukemia|Myelodysplastic/Myeloproliferative Neoplasms|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Relapsing Chronic Myelogenous Leukemia|Secondary Acute Myeloid Leukemia|T-cell Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: perifosine|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise to Boost Response to Checkpoint Blockade Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Melanoma|Cutaneous Squamous Cell Carcinoma|Merkel Cell Carcinoma
Interventions: OTHER: Exercise|DRUG: Checkpoint Blockade, Immune
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Prospective Cohort Study Comparing Random Biopsies Versus Wide-Area Transepithelial Brush-Sampling (WATS) for Surveillance of Barrett's Esophagus, the WATS-EURO2 Study
Status: RECRUITING
Conditions: Barrett Esophagus|Esophageal Adenocarcinoma|Diagnosis
Interventions: DIAGNOSTIC_TEST: WATS3D
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study of the Efficacy in Plaque Removal of Two Manual Toothbrushes
Status: COMPLETED
Conditions: Tooth Caries|Dental Plaque
Interventions: DEVICE: Curaprox 5460 Ultra Soft|DEVICE: Oral-B Indicator Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Well-being by Improving Memory for Treatment for Sleep and Circadian Dysfunction
Status: COMPLETED
Conditions: Sleep Disorder|Circadian Dysregulation
Interventions: BEHAVIORAL: Trans-C for sleep and circadian function + Memory Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Best Systemic Therapy or Best Systemic Therapy (BST) Plus Definitive Treatment (Radiation or Surgery)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Best Systemic Therapy (BST)|OTHER: Best Systemic Therapy (BST) + Surgery or Radiation Therapy|BEHAVIORAL: Questionnaires|OTHER: Phone Call/Email
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis
Status: COMPLETED
Conditions: Subjects Clinically Suspected an Active Source of Toxoplasmosis Chorioretinitis Infection
Interventions: OTHER: Fluorescein angiography|OTHER: Dilated fundus examination|BIOLOGICAL: Toxoplasmosis serology|DRUG: Anti-toxoplasmosis treatment|DRUG: Anti-inflammatory treatments|OTHER: Puncture in anterior chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Flash CONtinous Glucose Monitoring in TRansition to Outpatient: Libre for Type 2 Diabetes Mellitus (CONTROL-DM)
Status: UNKNOWN
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: Flash glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Subpleural Infusion of Bupivacaine
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Subpleural pain catheter with infusion of 0.125% bupivacaine|DRUG: Standard acute pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia
Status: COMPLETED
Conditions: Community-Acquired Bacterial Pneumonia|Lung Infection of Individual Not Recently Hospitalized
Interventions: DRUG: Ceftaroline|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects and Cost-effectiveness Analysis of Early Anti-viral Therapy on HBV-related Compensated Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Lamivudine plus Adefovir Dipivoxil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Musculoskeletal Ultrasound Program to Improve Disease Modifying Anti-Rheumatic Drugs Adherence in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Musculoskeletal ultrasound program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients
Status: WITHDRAWN
Conditions: Sepsis|Shock, Septic
Interventions: DIETARY_SUPPLEMENT: selenium replacement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing a Computer Delivered Tobacco Cessation Intervention in Outpatient Clinical Settings: A Feasibility Study
Status: COMPLETED
Conditions: Tobacco Smoking
Interventions: BEHAVIORAL: C-Raven with avatar|BEHAVIORAL: C-Raven without avatar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Midazolam|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy With or Without Epoetin Alfa in Treating Patients With Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: epoetin alfa|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of Immediate Versus Deferred Isoniazid Preventive Therapy Among HIV-Infected Pregnant Women
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Isoniazid (INH)|DRUG: Placebo for isoniazid (INH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Etanercept (ETN) Against a Placebo for Etanercept on a Background Nonsteroidal Anti Inflammatory Drug (NSAIDs) in the Treatment of Early Spondyloarthritis (SpA) Patients Who do Not Have X-ray Structural Changes
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: etanercept|DRUG: Background NSAID|OTHER: PLACEBO|DRUG: Background NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utilizing Continuous Glucose Monitoring to Characterize and Manage Hyperglycemia in Patients Initiating Alpelisib
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Alpelisib|DEVICE: FreeStyle Libre 2 Continuous Glucose Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Explore the Efficacy of DAPAglifozin as add-on to Closed-loop Control in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Modified Otago Exercises in Individuals With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Neuropathy
Interventions: OTHER: Exercise Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Achieve an Early Reendothelialization at the Expense of Low Restenosis: The EREMUS Study
Status: UNKNOWN
Conditions: Angioplasty, Transluminal, Percutaneous Coronary|Percutaneous Coronary Intervention
Interventions: DEVICE: Percutaneous coronary intervention: Paclitaxel eluting balloon (Elutax) + Genous stent|DEVICE: Percutaneous coronary intervention: Uncoated balloon + Genous stent|DEVICE: Percutaneous coronary intervention: Drug eluting stent (Taxus stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Augmenting TAK-659 Action in Relapsed/Refractory AML by Addition Ofthe Proteasome Inhibitor Ixazomib
Status: TERMINATED
Conditions: AML|AML, Adult
Interventions: DRUG: TAK-659|DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DEVICE: Epimacular Brachytherapy|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ
Status: COMPLETED
Conditions: Panic Disorder|Healthy
Interventions: DRUG: [18F] SPA-RQ
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Uncovering the Barriers of Colorectal Cancer Screening Amongst Siblings of Colorectal Cancer Patients.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Proactive engagement|BEHAVIORAL: Current practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer
Status: COMPLETED
Conditions: Metastatic Differentiated Thyroid Cancer|Metastatic Poorly Differentiated Thyroid Cancer|Metastatic Anaplastic Thyroid Cancer|Metastatic Medullary Thyroid Cancer
Interventions: DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC Consumers
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Ibuprofen 600 mg Immediate Release/Extended Release Caplet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clomiphene Citrate Plus uFSH Versus Aromatase Inhibitor Plus uFSH in Clomiphene Resistant Infertile PCOS Women
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: Aromatase inhibitor (litrezole) plus uFSH arm|DRUG: clomiphene citrate-uFSH arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Valacycovir HCl Tablets, 1000 mg of Dr. Reddy's Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valacyclovir Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies
Status: COMPLETED
Conditions: Osteoarthritis|Cancer Pain|Recurrent Low Back Pain
Interventions: DRUG: Investigational medical product (IMP) administered in parent study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcrestal Lateral Sinus Floor Elevation in Implant Therapy
Status: UNKNOWN
Conditions: Edentulous; Alveolar Process, Atrophy
Interventions: PROCEDURE: L-PRF|PROCEDURE: DBBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Complications of Peripheral Venous Access in the Type 2 Diabetic Population
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Catheterization, Peripheral|Upper Extremity Deep Vein Thrombosis|Catheter-Related Infections|Diabetes Complications
Interventions: DEVICE: Peripheral vascular catheters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bilateral Uterine Artery Ligation After Intrapartum or Postpartum Hemorrhage on Ovarian Reserve Markers and Pregnancy Outcome
Status: COMPLETED
Conditions: Bilateral Uterine Artery Ligation|Intrapartum or Postpartum Hemorrhage|Ovarian Reserve Markers|Pregnancy Outcome
Interventions: PROCEDURE: Bilateral uterine artery ligation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementing Group Battlefield Acupuncture in CCRCs for the Treatment of Chronic Lower Back Pain
Status: NOT_YET_RECRUITING
Conditions: Pain, Back
Interventions: DEVICE: Auricular acupuncture|BEHAVIORAL: Visual Analog Scale for Pain|BEHAVIORAL: Roland-Morris Disability Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sym004 Versus TAS-102 in Patients With mCRC
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer|Colorectal Cancer Metastatic|Carcinoma
Interventions: DRUG: Sym004|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study for Short-course Accelerated, Hypofractionated Partial Breast Radiotherapy (APBI) in Women With Early Stage Breast Cancer Using the Contura MLB
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: APBI (Dose Escalation)|DEVICE: Contura MLB Breast Brachytherapy Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cor Adv Flap Plus Ac Derm Matrix in Thin Phenotype Multiple Recessions
Status: COMPLETED
Conditions: Gingival Recession, Generalized
Interventions: PROCEDURE: Modified coronally advanced flap and acellular dermal matrix graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel for Injection (Albumin Bound)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 With DWC202307 in Healthy Adult Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: DWC202307|DRUG: DWJ1543|DRUG: DWC202216
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Corneal Endothelial Function Following Hypoxic Stress
Status: RECRUITING
Conditions: Fuchs' Endothelial Corneal Dystrophy
Interventions: DEVICE: Wearing of contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interventions to Increase Screening by Breast Cancer Survivors and Their High Risk Female Relatives
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer in Young Women|Breast Cancer in Women With a Strong Family History
Interventions: BEHAVIORAL: Targeted|BEHAVIORAL: Enhanced Tailored
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Spatially Resolved IBD: Spatial Transcriptomics of Inflammatory Bowel Disease (IBD)
Status: NOT_YET_RECRUITING
Conditions: Patients With Histologically Confirmed CD Undergoing Intestinal Resection According to Standard of Care Due to Complicating Disease|Patients With Histologically Confirmed UC Undergoing Intestinal Resection According to Standard of Care Due to Complicating Disease
Interventions: OTHER: transcriptomic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Antioxidants on Skin Blood Flow During Local Heating
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Vasodilation
Interventions: OTHER: Control (Lactated Ringer's)|DRUG: Tempol|DRUG: Apocynin|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Anaesthesia on Inflammatory Markers
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DRUG: Morphine Sulfate|DRUG: morphine+lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DOR/TDF/3TC Switch With M184V/I in People With Controlled HIV (Drive Off-Road)
Status: NOT_YET_RECRUITING
Conditions: Hiv
Interventions: DRUG: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increased Gluconeogenesis is One Cause of Cystic Fibrosis Related Diabetes (CFRD)
Status: COMPLETED
Conditions: Cystic Fibrosis|Diabetes Mellitus
Interventions: OTHER: Stable isotopes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lycopene or Green Tea for Men at Risk of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Green tea drink|DIETARY_SUPPLEMENT: green tea capsules|OTHER: Green tea placebo capsules|DIETARY_SUPPLEMENT: Lycopene capsules|OTHER: Lycopene placebo capsules|OTHER: Tomato rich diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of 3 Different Formulations of BI 207127 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 207127|DRUG: BI 207127|DRUG: BI 207127
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Knee Injections in Musculoskeletal Medicine
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Joint line ultrasound|PROCEDURE: Joint line landmark|PROCEDURE: Suprapatellar ultrasound guided|PROCEDURE: Suprapatellar Landmark
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Gonadotropin Replacement Therapy in Patients With Hypogonadism
Status: COMPLETED
Conditions: Idiopathic Hypogonadotropic Hypogonadism
Interventions: DRUG: hCG 1500 IU three times a week|DRUG: Pregnyl (hCG) ampule 1500 IU/three times a week
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Armeo Spring Robotic Therapy in the Function of the Upper Limb of Children With Unilateral Spastic Cerebral Palsy Infiltrated With Botulinum Toxin
Status: COMPLETED
Conditions: Cerebral Palsy|Upper Extremity Paresis
Interventions: DEVICE: Armeo spring|OTHER: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Executive Training for ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: CET: Central Executive Training|BEHAVIORAL: CET: Comparison Executive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide Therapy for Refractory Antibody-Mediated Rejection (AMR) in Kidney Transplants
Status: TERMINATED
Conditions: Antibody Mediated Rejection
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Factors and Side Effects of Metoclopramide and Diphenhydramine
Status: TERMINATED
Conditions: Drug Metabolism, Poor, CYP2D6-RELATED
Interventions: DRUG: Diphenhydramine|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Robotic Sock Technology for Prevention of Deep Vein Thrombosis and Joint Contracture
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Ankle Joint Contracture
Interventions: DEVICE: Robotic Sock|DEVICE: Intermittent pneumatic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: DRUG: ACTIVA™ BioACTIVE|DRUG: Compomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Zemplar Capsule in Reducing Serum IPTH Levels in Chronic Kidney Disease Subjects (Three Times Weekly)
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Antiviral Effects of TXA as a Preventative Treatment Following COVID-19 Exposure
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Gemigliptin 50mg|DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Premenstrual Symptoms Treatment Comparing Between Oral Contraceptives Containing Desogestrel and Drospirenone
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: DRUG: EE 20 microgram with desogestrel 150 mg|DRUG: EE 20 microgram with drospirenone 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Isosorbide Mononitrate Therapy on Umbilical Artery Doppler Resistance Index in Pregnancies With Intrauterine Growth Restriction: Prospective Randomized Control Trial
Status: COMPLETED
Conditions: Intrauterine Growth Restriction
Interventions: DRUG: Isosorbid mononitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Drug Levels of Atazanavir and Cobicistat Between the Coadministration of Age-Appropriate Mini-Tablet Formulations and the Coadministration of the Individual Reference Products in Healthy Adults Under Fed Conditions
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Atazanavir|DRUG: Cobicistat|DRUG: Atazanavir/Cobicistat Mini-tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Stage I and Stage II Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: olmesartan medoxomil + hydrochlorothiazide, if necessary|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Maintenance Through Physical Activity and Social Support in Rural Middle-Aged Women
Status: COMPLETED
Conditions: Body Weight Changes
Interventions: BEHAVIORAL: Videos|BEHAVIORAL: Action Plans|BEHAVIORAL: Discussion Boards|BEHAVIORAL: Health behavior tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Roniciclib (BAY1000394)|DRUG: Etoposide|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lidocaine and Benzocaine on Pain and Injection Satisfaction in Peripheral Intravenous Catheter Application
Status: COMPLETED
Conditions: Peripheral Intravenous Catheterization Application
Interventions: DRUG: Lidocaine Spray|DRUG: Benzokain Sprey|OTHER: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Dapagliflozin on Microvascular and Macrovascular Circulation and Total Body Sodium Content
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combining Low Level Laser Therapy With Cognitive-behavioral Therapy on Myalgia in Temporomandibular Joint Disorders
Status: RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: BEHAVIORAL: Cognitive behavioral treatment (CBT)|RADIATION: Low level laser therapy combined with CBT (LLLT+CBT)|DEVICE: Occlusal Splint combined with CBT (OS+CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasciectomy vs Collagenase Injection in Recurrent Dupuytren Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Dupuytren Disease of Finger
Interventions: PROCEDURE: Fasciectomy|DRUG: Collagenase Clostridium Histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TOTEM RRMS : TestOsterone TreatmEnt on Neuroprotection and Myelin Repair in Relapsing Remitting Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Nebido® Testosterone Undecanoate 1000 Mg/4 mL Solution for Injection|DRUG: Placebo 4 mL Solution for Injection|PROCEDURE: MRI|BEHAVIORAL: Assessment of impact of MS on cognition; quality of life; fatigue; anxiety/depression and work and activities|BEHAVIORAL: Assessment of disability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin and Patient Support Program in Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ombitasvir/paritaprevir/ritonavir|DRUG: Dasabuvir|DRUG: Ribavirin|BEHAVIORAL: Patient support program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study
Status: COMPLETED
Conditions: Coronary Artery Occlusive Disease
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Metastatic Non Small Cell Lung Cancer|NSCLC|Metastatic NSCLC - Non-Small Cell Lung Cancer
Interventions: PROCEDURE: Core Needle or Forceps Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Sufentanil NanoTab PCA System/15 mcg|DRUG: morphine IV PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of「GTT-EGCG」on Acne Women
Status: UNKNOWN
Conditions: Acne Lesion Counts
Interventions: DIETARY_SUPPLEMENT: green tea extract EGCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Indacaterol 150 mcg Once Daily (o.d.) With Salmeterol/Fluticasone Propionate 50 mcg/500 mcg Twice Daily (b.i.d.)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quality of Life in Moderate Acne Vulgaris Patients Based on Acne-QoL-INA Using Standard Therapy With and Without Acne Lesions Extraction
Status: ACTIVE_NOT_RECRUITING
Conditions: Acne Vulgaris|Quality of Life
Interventions: PROCEDURE: Lesion extraction|DRUG: Tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phrenic Nerve Infiltration: Pulmonary Expansion and Pain Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Prolonged Air Leak|Post-operative Pain
Interventions: PROCEDURE: intra-operative phrenic nerve infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Double Antibiotic Paste Versus Calcium Hydroxide on RANKL/OPG Levels
Status: UNKNOWN
Conditions: Biological Markers
Interventions: DRUG: Double Antibiotic paste|DRUG: Calcium Hydroxide Paste - Non-Setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviewing and Education Based on Watson's Theory of Human Caring in Hemodialysis
Status: COMPLETED
Conditions: Renal Disease|Adherence, Treatment|Quality of Life|Satisfaction, Patient
Interventions: OTHER: Motivational Interviewing and Education Based on Watson's Theory of Human Caring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnetic Brain Stimulation for the Treatment of Adult Depression
Status: COMPLETED
Conditions: Depression
Interventions: PROCEDURE: Prefrontal rTMS|DRUG: Antidepressant Regimen|PROCEDURE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ways to Prepare Patients for Decisions About Joint Replacement Surgery
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BEHAVIORAL: Patient decision aid|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury With Loss of Consciousness|Brain Injury Traumatic Severe|Brain Injury Traumatic Moderate|TBI (Traumatic Brain Injury)|TBI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain Interstitium Temozolomide Concentration Pre and Post Regadenoson Administration
Status: COMPLETED
Conditions: Blood Brain Barrier Defect
Interventions: DRUG: Regadenoson|DRUG: Temozolomide|DEVICE: Microdialysis catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Standard-Dose Rituximab, Ifosfamide, Carboplatin and Etoposide (RICE) Plus Bortezomib (Velcade) in a Dose-Escalating Fashion for Patients With Relapsed or Primary Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma Who Are Candidates for Autologous Stem Cell Transplant
Status: TERMINATED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Rituximab, Ifosfamide, Carboplatin, Etoposide, Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX Plus IPI-926 for Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer|Adenocarcinoma|Pancreatic Neoplasms
Interventions: DRUG: FOLFIRINOX, IPI-926
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Navigation Brain Stimulation for Evaluation of the Neuroprotective Drug Efficiency in Patients After Ischemic Stroke.
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: citicoline|DRUG: L-Alpha glycerylphosphorylcholine|DRUG: cerebrolysin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Olaparib in Advanced Cancers Occurring in Patients With Germline Mutations or Somatic Tumor Mutations in Homologous Recombination Genes
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancers Harbouring Mutations in HRG
Interventions: DRUG: Olaparib Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Are CK+/CD45+ Double-Positive Circulating Cells of Tumor-origin? Characterization in METAstatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: OTHER: For each patient included, the samples described below will be collected:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion
Status: RECRUITING
Conditions: Central Retinal Artery Occlusion
Interventions: DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Neuromodulation Therapy (PNT) With Chronic Low Back Pain Patients
Status: TERMINATED
Conditions: Low Back Pain
Interventions: DEVICE: Vertis Percutaneous Neuromodulation Therapy (PNT)|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High and Low Intensity Percutaneous Electrolysis for the Treatment of Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Knee Pain Chronic|Muscle Pain
Interventions: PROCEDURE: Percutaneous Electrolysis|PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor Plus Emtricitabine/Tenofovir Fixed-Dose Combination to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected Patients
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: PI|DRUG: RTV|DRUG: FTC/TDF|DRUG: Stribild
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physician-modified Endovascular Graft for Repair of Complex Thoracoabdominal and Abdominal Aortic Aneurysms
Status: RECRUITING
Conditions: Juxtarenal Aortic Aneurysm|Suprarenal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: Physician-Modified Cook Zenith Alpha Thoracic Endovascular Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Obesity to Optimize Health in Cardiac Rehab (TOPCARE)
Status: COMPLETED
Conditions: Obesity|Weight Loss|CHD - Coronary Heart Disease
Interventions: OTHER: Exercise|BEHAVIORAL: Health Education|OTHER: Exercise Compliance|DIETARY_SUPPLEMENT: Calorie-Restricted Diet|BEHAVIORAL: Behavioral Modification|OTHER: Weight-Loss Compliance|OTHER: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass
Status: RECRUITING
Conditions: Obesity, Morbid|Weight Gain
Interventions: PROCEDURE: Distal gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Product Related Factors on Platelet Concentrate Transfusion Response in Patients With Hematologic Malignacies
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma|Lymphocytic Leukemia|Hodgkin Disease
Interventions: OTHER: Platelet concentrate transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Pharmacokinetics and Safety Study of OvaRex MAb-B43.13 in Patients With Ovarian Epithelial Carcinoma
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: DRUG: oregovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: DRUG: pitavastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Supreme During Laparoscopic Gynecologic Surgery
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DEVICE: Laryngeal Mask Airway-Supreme|DEVICE: Endotracheal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Ventilatory Strategies During Laparoscopic Surgery
Status: COMPLETED
Conditions: Pneumonia
Interventions: PROCEDURE: First arm: patients ventilated with zero end expiratory pressure|PROCEDURE: Patients ventilated with Positive End Expiratory Pressure|PROCEDURE: Patients ventilated with Positive End Expiratory Pressure plus Recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole With Sildenafil Citrate in Women With Early-onset Preeclampsia
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Esomeprazole with Sildenafil Citrate|DRUG: Sildenafil Citrate|DRUG: Placebo to Esomeprazole|DRUG: Placebo to Sildenafil Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.
Status: NOT_YET_RECRUITING
Conditions: Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)|Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)
Interventions: DRUG: ARV-393
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD
Status: COMPLETED
Conditions: Sickle-Cell Disease
Interventions: DRUG: Sevuparin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transapical Implantation of Ventor Embracer™ Valve in Patients With Severe Aortic Valve Disease
Status: UNKNOWN
Conditions: Aortic Valve Disease
Interventions: DEVICE: Ventor Embracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|Lung Cancer|Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Stage IIIB|Stage IV Non-small Cell Lung Cancer|EGFR Negative Non-Small Cell Lung Cancer
Interventions: DRUG: Ceritinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Traditional Herbal Dietary Supplements on General Fatigue and Negative Emotions of Graduate Students
Status: RECRUITING
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Traditional Herbal Supplements (Kuan Sin Yin)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: L.Fermentum CECT5716 in Treatment of Breast Pain
Status: COMPLETED
Conditions: Breast Pain
Interventions: DIETARY_SUPPLEMENT: Lactobacillus fermentum CECT5716|OTHER: Placebo Comparator: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT