pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Dexmedetomidine on the Quality of Recovery in Parturients Undergoing Elective Caesarean Sections
Status: COMPLETED
Conditions: The Quality of Recovery (ObsQOR-11)
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perineal Massage Combined With Hip Joint Training
Status: NOT_YET_RECRUITING
Conditions: Pelvic Floor Disorders
Interventions: PROCEDURE: perineal massage combined hip joint training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metagenomic and Metabolomic Reconstitution of Gut Microbiota After Broad Spectrum Antibiotic Therapy
Status: COMPLETED
Conditions: Antibiotic Side Effect|Antibiotic-associated Diarrhea|Antibiotic-induced Dysbiosis|Antibiotic-induced Epithelial Barrier Disintegrity
Interventions: OTHER: Ciprofloxacin + Metronidazole|OTHER: SH-DS01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: InterStim Micro Post Market Clinical Follow-up Study
Status: TERMINATED
Conditions: Overactive Bladder|Fecal Incontinence|Non-obstructive Urinary Retention
Interventions: DEVICE: InterStim Micro
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Patiromer|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Bioavailability Study of Azithromycin 200mg/5mL Suspension Following a 600mg Dose Under Fed Conditions
Status: COMPLETED
Conditions: Infections
Interventions: DRUG: Azithromycin for Oral Suspension 200mg/5mL Eon Pharma, LLC|DRUG: Zithromax (azithromycin for oral suspension) 200mg/5mL Pfizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mild Hypercapnia During Anesthetic Emergence on Recovery Time From TIVA
Status: UNKNOWN
Conditions: Total Intravenous Anesthesia
Interventions: PROCEDURE: mild hypercapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Neurocognitive Disorder and Low Near-infrared Spectrometry is Associated With Postoperative Delirium
Status: UNKNOWN
Conditions: Neurocognitive Disorders|Postoperative Period|Postoperative Complications
Interventions: DIAGNOSTIC_TEST: Mini-Mental State Examination (MMSE)|DIAGNOSTIC_TEST: Visual Analog Scale (VAS)|DIAGNOSTIC_TEST: Mini Cog test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Study of Methicillin-Resistant Staphylococcus Aureus (MRSA) Among HIV-Infected Persons
Status: COMPLETED
Conditions: HIV Infections|Staphylococcal Infections
Interventions: DRUG: Mupirocin (Bactroban) 2%; hexachlorophene (pHisoHex) 3%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Solute Removal With High Volume Hemodiafiltration Versus Long High Flux Hemodialysis
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DEVICE: High volume post dilution hemodiafiltration|DEVICE: high flux hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy of 0.01% Atropine for Near Work-induced Transient Myopia and Myopic Progression
Status: RECRUITING
Conditions: Myopia
Interventions: DRUG: 0.01% atropine|OTHER: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Personalized First-line Chemotherapy Choice in Advanced Pancreatic Adenocarcinoma Using Transcriptomic Signatures
Status: RECRUITING
Conditions: Carcinoma, Pancreatic Ductal|Prognosis
Interventions: OTHER: Clinical value of 5 transcriptomic signatures to personalize the therapeutic decision for L1 in PDAC|OTHER: Biomarkers of tumor signatures (translational studies)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Non-Randomized, Open-Label, Single Center Phase 4 Study of the Effect and Safety of ILUVIEN® in Chronic Diabetic Macular Edema Patients Considered Insufficiently Responsive to Available Therapies (Laser, Anti-VEGF) With or Without Intravitreal Corticosteroid Therapy
Status: COMPLETED
Conditions: Chronic Diabetic Macular Edema
Interventions: DRUG: ILUVIEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supraclavicular Versus Interscalene Block
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: Interscalene block|PROCEDURE: Supraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of HFA-152a and HFA-134a Propellants on Mucociliary Clearance in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: OTHER: HFA-152a|OTHER: HFA-134a|OTHER: Radiolabeled saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Emtansine Versus Capecitabine + Lapatinib in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab emtansine|DRUG: Lapatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Airway Complication of Anesthesia
Interventions: DEVICE: CMAC D-blade videolaryngoscope with full or partial glottic view
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of CR6261 in Japanese Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: CR6261|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Frequency Oscillatory Highflow Nasal Cannula on Desaturations and Bradycardia in Preterm Infants
Status: COMPLETED
Conditions: Apnea of Prematurity|Infant, Premature, Diseases
Interventions: DEVICE: Osciflow|DEVICE: Highflow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managed Access Programs for PKC412, Midostaurin
Status: NO_LONGER_AVAILABLE
Conditions: FMS-Like Tyrosine Kinase 3 (FLT3)-Mutated Acute Myeloid Leukemia|Acute Myeloid Leukemia|Aggressive Systemic Mastocytosis|Mast Cell Leukemia|Systemic Mastocytosis With an Associated Hematologic Neoplasm
Interventions: DRUG: midostaurin
Study Type: EXPANDED_ACCESS
Clinical trial: Safety and Antiviral Activity of IDX184 in Combination With Pegylated Interferon and Ribavirin (MK-2355-004)
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: IDX184|DRUG: Placebo|BIOLOGICAL: Peginterferon alfa-2a (Peg-IFN)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UCB8600 in Healthy Participants, Atopic Participants, and Chronic Spontaneous Urticaria Participants
Status: TERMINATED
Conditions: Healthy Study Participants|Chronic Spontaneous Urticaria
Interventions: DRUG: UCB8600|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypersensitivity|Hay Fever|Rhinitis, Allergic, Seasonal|Rhinoconjunctivitis
Interventions: BIOLOGICAL: Polvac Grass+Rye
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of a Shared Decision Aid Tool for Cardiovascular Risk Prevention in Hypercholesterolemic Patients
Status: COMPLETED
Conditions: Hypercholesterolemia|Cardiovascular Risk
Interventions: BEHAVIORAL: Share decision tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With Men
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA plasmid vaccine|BIOLOGICAL: Recombinant adenoviral serotype 5 (rAD5) vector vaccine|BIOLOGICAL: DNA vaccine placebo|BIOLOGICAL: HIV-1 recombinant adenovirus vaccine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Community Home-based Care Intervention and Its Health Outcome in HIV-positive People
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Depression|Stress|Anxiety|Quality of Life
Interventions: BEHAVIORAL: Community home-based care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of HICT and Intermittent Fasting on PCOS
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|PCO
Interventions: OTHER: High Intensity Circuit training (HICT)|OTHER: Intermittent Fasting (IF)|OTHER: Combination of HICT and IF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Combination Steroid and Anti-VEGF for Persistent DME
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: intravitreal ranibizumab 0.3 mg|DRUG: dexamethasone intravitreal implant|PROCEDURE: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tidal Irrigation Versus Intra-articular Steroid Injection in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Intra-articular CSI|PROCEDURE: TI of the knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deep TMS on the Permeability of the BBB in Patients With Glioblastoma Multiforme: a Pilot Study
Status: COMPLETED
Conditions: Glioblastoma Multiforme of Brain
Interventions: DEVICE: Deep Transcranial Magnetic Stimulation (dTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Romiplostim to Treat Low Platelet Counts During Chemotherapy in People With Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma Patients|Thrombocytopenia
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myofunctionnal Therapy on Nasal Breathing and Orthodontic Corrections Stability
Status: COMPLETED
Conditions: Mouth Breathing|Atypic Swallowing|Low Resting Position of Tongue
Interventions: BEHAVIORAL: Myofunctionnal therapy|BEHAVIORAL: instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Relaxation for Pediatric Adenotonsillectomy
Status: RECRUITING
Conditions: Tonsillectomy
Interventions: DRUG: Rocuronium|DRUG: Sugammadex|OTHER: Anesthesia without neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breast Milk Zinc Transfer to Appropriate- and Small-for-gestational-age Bangladeshi Infants
Status: COMPLETED
Conditions: Small for Gestational Age at Delivery|Post-term Infant, Not Heavy-for-dates
Interventions: OTHER: Small for gestational age at delivery|OTHER: Post-term Infant, Not Heavy-for-dates
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Evaluation Of Outcomes For Patients Undergoing Radiofrequency Ablation (RFA) Using HALO Ultra Device For Gastric Antral Vascular Ectasia (GAVE)
Status: RECRUITING
Conditions: Gastric Antral Vascular Ectasia
Interventions: OTHER: Radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mean Visual Acuity Changes Following Five Injections of Aflibercept
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Aflibercept Injection [Eylea]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.
Status: COMPLETED
Conditions: Glaucoma|Blindness, Acquired|End-Stage Glaucoma|Glaucoma Traumatic
Interventions: DEVICE: Laminar drainage implant surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Antibacterial Effect of the Infusion of Green Tea Used as a Mouthwash on Saliva and Bacterial Plaque
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: Green Tea mouthwash|OTHER: Placebo Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Investigation of the ClarVista HARMONI™ Modular Intraocular Lens Implant Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Harmoni Modular Intraocular Lens|DEVICE: Commercially Available Intraocular Lens|PROCEDURE: Optic exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Versus Infliximab in New Onset Crohn's Disease With Poor Prognostic Factors
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DRUG: Thalidomide|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of EBT With Young, Substance Abusing Homeless Mothers
Status: COMPLETED
Conditions: Substance Use
Interventions: BEHAVIORAL: Ecologically Based Therapy|BEHAVIORAL: Housing Only|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Tracer PET Assessment of Primary Brain Tumors
Status: COMPLETED
Conditions: Brain Tumors|Cancer
Interventions: DRUG: [18F]fluoro-2-deoxy-D-glucose (FDG)|DRUG: 3'-deoxy-3'-[18F]fluorothymidine (FLT)|DRUG: [15O]-H2O|DRUG: [11C]Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Hodgkin Lymphoma|Hodgkin Lymphoma|Myeloma|Lymphocytic Leukemia
Interventions: DRUG: BMS-986345|DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone to Treat Cervical Cancer
Status: TERMINATED
Conditions: Cervical Carcinoma|Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Carcinoma, Non-SquamousType
Interventions: DRUG: Ixempra (Ixabepilone (BMS-247550) )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno-humoral Rejection Markers in Pulmonary Transplant
Status: COMPLETED
Conditions: Lung Transplant
Interventions: BIOLOGICAL: Blood test for detecting the circulatory anti-HLA antibodies by ELISA and LUMINEX tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PET/MRI Study of Men With Highly Suspicious MRI Lesions That Showed no Clinically Significant Prostate Cancer Following MRI Fusion Targeted Biopsy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Fluciclovine PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Plant-Based Omega-3 Fatty Acids and Molecular Characterisation in Individuals With Cardiovascular(CVD) Risk
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Risk
Interventions: DIETARY_SUPPLEMENT: Plant Omega|OTHER: Dietary therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fluticasone Furoate on Methacholine Challenge
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate|OTHER: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus Corticosteroids in Non-infectious Active Mixed Cryoglobulinemia Vasculitis
Status: TERMINATED
Conditions: Cryoglobulinemia|Systemic Vasculitis
Interventions: DRUG: rituximab|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Transplant To End NMO Spectrum Disorder
Status: WITHDRAWN
Conditions: Neuromyelitis Optica|Devic's Disease|NMO Spectrum Disorder
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: rATG|DRUG: Methylprednisolone|DRUG: G-CSF|BIOLOGICAL: IVIg|BIOLOGICAL: Autologous Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: #KindGirlsInACTion: A Programme for the Promotion of Mental Health of Female Adolescents
Status: COMPLETED
Conditions: Quality of Life|Eating Disorders|Eating Behavior|Psychological|Emotion Regulation|Body Image|Relations, Interpersonal
Interventions: BEHAVIORAL: #KindGirlsInACTion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation of the Multifocal IOL POD F GF in Cataracteous Eyes
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: Assigned Intervention (POD F GF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Solid Tumor|Gastric Cancer|Pancreas Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: TORL-2-307-ADC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of CDX-6114 in Patients With Phenylketonuria (PKU)
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: CDX 6114|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of CT-P27 in Acute Uncomplicated Influenza A Infection
Status: TERMINATED
Conditions: Influenza A
Interventions: DRUG: CT-P27 90 mg/kg|DRUG: CT-P27 45 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diamel in the Treatment of Type 2 Diabetic Patients Receiving Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Diamel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation(IRE) For Unresectable Lymph Node Metastases(Close to Nerve)
Status: COMPLETED
Conditions: Lymph Node Metastases
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Diclofenac Sodium Active Topical Patch 1|DRUG: Diclofenac Sodium Active Topical Patch 2|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Decision Support Systems for Smokers With Severe Mental Illness
Status: COMPLETED
Conditions: Severe Mental Illness|Nicotine Dependence|Schizophrenia|Tobacco Use Disorder
Interventions: BEHAVIORAL: EDSS with CO feedback and health checklist|BEHAVIORAL: EDSS with health checklist feedback alon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Plus Radiotherapy Alone in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: gemcitabine and cisplatin; docetaxel, cisplatin and fluorouracil|RADIATION: IMRT|RADIATION: IMRT and concurrent cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-770|DRUG: VX-770
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Synvisc (Hylan G-F20; hyaluronan injection)|DRUG: Bupivicaine (local anesthesia injection)|DRUG: Kenalog (triamcinolone; corticosteroid injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP)
Status: TERMINATED
Conditions: Critical Illness|Acute Respiratory Failure
Interventions: DRUG: Olimel (5.7%E / N9E)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Decitabine as Induction Therapy for Acute Myeloid Leukemia With Complex and/or Monosomal Karyotype
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Complex Karyotype
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bilberry and Oat Intake After Type 2 Diabetes and/or MI
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DIETARY_SUPPLEMENT: Bilberry|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Bioprocessed oat bran|DIETARY_SUPPLEMENT: Combination bilberry/oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of F2695 on Brain Activity Measured by Functional Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Subject
Interventions: DRUG: F2695|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BfedBwell Proof-of-Concept Pilot
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivorship|Obesity|Overweight
Interventions: BEHAVIORAL: Group-based education and discussion|BEHAVIORAL: Individual 1:1 counseling|BEHAVIORAL: Group based behavioral skills development and cooking demonstrations|BEHAVIORAL: BfitBwell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating SARS-CoV-2 (COVID-19) Humoral Response After BNT162b2 Vaccine in Immunocompromised Adults Compared to Healthy Adults
Status: COMPLETED
Conditions: Kidney Transplant|Myeloma|Cancer|Hematologic Malignancy|Multiple Sclerosis|Hypergammaglobulinemia|Malignant Tumor|Hiv|Diabetes Type 2
Interventions: BIOLOGICAL: Biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Emotion Recognition in Benign Epilepsy of Childhood With Centro-Temporal Spikes (BECTS)
Status: UNKNOWN
Conditions: BECTS|Epilepsy, Rolandic
Interventions: DIAGNOSTIC_TEST: IDS;MMSPE;CDI 2;CBCL;tests of facial expression evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Effect of Exercise Intensity With Nutritional Supplementation on Skeletal Muscle Function
Status: COMPLETED
Conditions: Healthy Volunteers|Exercise Intensity|Neuromuscular Fatigue|Skeletal Muscle Adaptations
Interventions: DIETARY_SUPPLEMENT: Olive leaf extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Iron Oligosaccharide in Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease|Anemia, Iron-Deficiency
Interventions: DRUG: Iron oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Protective Efficacy of Genetically Attenuated GA2 Parasites.
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: OTHER: GA2|OTHER: GA1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Active rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cross-Sectional Survey to Evaluate Diabetes Management, Control, Complications, Psychosocial Aspects of Patients With Type 2 Diabetes in Bangladesh, Indonesia, Malaysia, Philippines, Sri Lanka and Vietnam
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: OTHER: No treatment given
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of PEEP on Optic Nerve Sheath Diameter During Robot-Assisted Laparoscopic Prostatectomy
Status: COMPLETED
Conditions: Other Surgical Procedures
Interventions: OTHER: PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot Study
Status: COMPLETED
Conditions: Inflammation
Interventions: DIETARY_SUPPLEMENT: Omega-3 fish oil|DRUG: Losartan|OTHER: Corn Oil (Fish oil Placebo)|OTHER: Cellulose Based (Losartan Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Irritation Potential of Products in Human Eyes
Status: COMPLETED
Conditions: Sunscreening Agents
Interventions: OTHER: Sunscreen lotion SPF (Sun Protection Factor) 50 (BAY987521)|OTHER: Ophthalmic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Catheter-based Radiofrequency Ablation Therapy in Patient With Therapy-resistant Hypertension and Sleep Apnea Syndrome
Status: WITHDRAWN
Conditions: Therapy-resistant Hypertension and Sleep Apnea
Interventions: OTHER: No intervention will be done. The study is observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of Non Celiac Gluten Sensitivity Among Patients Spontaneously Adherent to Gluten Free Diet
Status: UNKNOWN
Conditions: Non Celiac Gluten Sensitivity
Interventions: OTHER: gluten|OTHER: gluten free flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evolution With CPAP Treatment of a Cohort of Type 2 Diabetic Patients With Apnea-hypopnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea|Type 2 Diabetes
Interventions: DEVICE: Continuous Positive Airway Pressure CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a 12-week Self-composed Vegan Diet With or Without Concurrent Resistance Exercise on Thigh Muscle Volume in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Vegan Diet|Sarcopenia|Cardiovascular Health|Osteoporosis|Gut Health
Interventions: OTHER: Vegan diet|OTHER: Resistance exercise|OTHER: Omnivorous diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of MEDI-524 (Motavizumab) for the Prophylaxis of Serious Respiratory Syncytial Virus (RSV) Disease in High-Risk Children
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: motavizumab (MEDI-524)|BIOLOGICAL: palivizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cortical Bone Plate Versus Cortico-cancellous Block Graft
Status: COMPLETED
Conditions: Horizontal Atrophy of Edentulous Alveolar Ridge
Interventions: PROCEDURE: Split-block technique|PROCEDURE: Cortico-cancellous block graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tract Microbiome in Healthy Term Infants Receiving Mother'S-own Breast Milk or Cow's Milk-based Infant Formulas
Status: TERMINATED
Conditions: Gastrointestinal Microbiome
Interventions: OTHER: Investigational|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of Single-use Fibrous Ring Sutures for the Suture of Fibrous Ring Incision After Nucleus Pulposus Removal
Status: NOT_YET_RECRUITING
Conditions: Intervertebral Disc Disorder
Interventions: DEVICE: Disposable fibrous ring sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Participant Preference of Subcutaneous (SC) Versus Intravenous (IV) Herceptin (Trastuzumab) in Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Herceptin|DRUG: Herceptin|DEVICE: Single-Use Injection Device|DEVICE: Single-Use Injection Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selective Prevention Transdiagnostic Intervention for At-risk Adolescents
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Depressive Symptoms
Interventions: BEHAVIORAL: PROCARE+ (with add-on modules)|BEHAVIORAL: PROCARE (UP-A for selective purposes)|BEHAVIORAL: Active control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medical Student Counseling for Hospitalized Patients Addicted to Tobacco
Status: COMPLETED
Conditions: Smoking Cessation Counselling|Medical Student Education
Interventions: BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset
Status: TERMINATED
Conditions: Mild Cognitive Impairment Due to Alzheimer's Disease
Interventions: DRUG: Pioglitazone|DRUG: Pioglitazone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy
Status: RECRUITING
Conditions: Neuromuscular Blockade|Laparoscopy
Interventions: DEVICE: low-pressure pneumoperitoneum|DEVICE: standard-pressure pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Curcumin on Lung Inflammation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Curcumin+Bioprine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study on Effect of Thymosin Beta 4 on Wound Healing in Patients With Epidermolysis Bullosa
Status: TERMINATED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Thymosin Beta 4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalised Responses to Dietary Composition Trial
Status: UNKNOWN
Conditions: Diabetes|Heart Diseases|Diet Habit|Diet Modification|Microbial Colonization|Healthy|Obesity|Metabolism
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: sorafenib tosylate|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)
Interventions: DRUG: Epcoritamab|DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Pharmacokinetics of FCN-437c Capsule and Its Effect on QT Interval in Healthy Subjects
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Low dose group|DRUG: High dose group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers
Status: COMPLETED
Conditions: Drug-drug Interaction
Interventions: DRUG: DWC202005, alone|DRUG: DWP14012 + DWC202005|DRUG: DWP14012 + DWC202005, after multiple doses of DWP14012
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DIETARY_SUPPLEMENT: Dietary Fiber|DIETARY_SUPPLEMENT: Fish Oil|OTHER: Comparator|OTHER: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Intensified Cyclophophamide, Carboplatin and Thiotepa|DRUG: dose dense adriamycine and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Neovascular Age Related Macular Degeneration or Macular Edema Secondary To Retinal Vein Occlusion to Evaluate Usability of the Ranibizumab (Lucentis®) Prefilled Syringe (PFS)
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Helfer Skin Tap Technique and ShotBlocker Technique
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: PROCEDURE: Helfer Skin Tap Technique group|PROCEDURE: ShotBlocker Technique group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Health Education and Counseling in Smoking Cessation Behavior, Smoking Decisional Balance, and Self-efficacy
Status: COMPLETED
Conditions: Coronary Heart Disease|Smoking Cessation|Smoking Behaviors
Interventions: BEHAVIORAL: health education and counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Plus Bevacizumab in First Line NSCLC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab-Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFICIENCY OF TECHNOLOGY-BASED MOTIVATION EDUCATION ON OBESITY UNIVERSITY STUDENTS' WEIGHT MANAGEMENT.
Status: UNKNOWN
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Technology Based Motivation Education Program|OTHER: Web Based Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cell Therapy in Myocardial Infarction
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Autologous Bone Marrow Mononuclear Cells (ABMMC) Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Eculizumab in Guillain-Barré Syndrome
Status: COMPLETED
Conditions: Guillain-Barre Syndrome
Interventions: BIOLOGICAL: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Residue Diet During 3 Days vs 1 Day Prior Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Colon Adenoma|Colorectal Neoplasms|Inflammatory Bowel Diseases|Colon Disease
Interventions: OTHER: 1 day low residue diet|OTHER: 3 day low residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer
Status: RECRUITING
Conditions: ER+ Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: Palbociclib 125Mg Tab|DRUG: Fulvestrant injection|DRUG: Tamoxifen|DRUG: Letrozole|DRUG: Exemestane|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment (MCI)
Interventions: BEHAVIORAL: Behavioral Activation (BA)|BEHAVIORAL: Supportive Therapy (ST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Pembrolizumab for Muscle-invasive Urothelial Bladder Carcinoma
Status: COMPLETED
Conditions: Urothelial Bladder Carcinoma
Interventions: DRUG: Pembrolizumab (MK-3475)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Theragnostic Value of Osimertinib in EGFR-mutated Lung Cancer (THEROS)
Status: COMPLETED
Conditions: NSCLC|EGFR T790M|FDG-PET
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis|Hepatic Impairment
Interventions: DRUG: Efinopegdutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UPLYFT For Lymphoma Survivors
Status: RECRUITING
Conditions: Lymphoma|Survivorship
Interventions: OTHER: Interview with Clinicians|OTHER: Field Test of UPLYFT with Lymphoma Survivors|BEHAVIORAL: Pilot of UPLYFT with Lymphoma Survivors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ovarian Reserve After Ovarian Hemostasis by Floseal Matrix
Status: COMPLETED
Conditions: Ovarian Cysts
Interventions: PROCEDURE: Floseal|PROCEDURE: Bipolar coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Tinnitus
Interventions: BEHAVIORAL: Cognitive Processing Therapy (CPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Purified Vero Rabies Vaccine
Status: COMPLETED
Conditions: Rabies Virus
Interventions: BIOLOGICAL: VRVg 2|BIOLOGICAL: VRVg 1|BIOLOGICAL: Imovax Rabies|BIOLOGICAL: VRVg 2|BIOLOGICAL: VRVg 2|BIOLOGICAL: Human Rabies Immunoglobulins (HRIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT