pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hemopatch Versus Axillary Drainage After Axillary Lymphadenectomy
Status: COMPLETED
Conditions: Breast Cancer|Breast-conserving Surgery|Axillary Lymph Node Dissection
Interventions: DEVICE: hemopatch|PROCEDURE: Aspirative drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Tunnel Technique and Free Gingival Graft in Gingival Recessions Treatment
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Tunnel technique|PROCEDURE: Laterally closed tunnel technique|PROCEDURE: Free gingival graft|PROCEDURE: Gingival graft - donor area
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of the 9vHPV Vaccination 2-dose Regimen Among Children 4 to 8 Years Old, An Exploratory Immunogenicity Study
Status: RECRUITING
Conditions: Human Papilloma Virus
Interventions: DRUG: Gardasil9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin
Status: COMPLETED
Conditions: Non-Insulin-Dependent Diabetes Mellitus
Interventions: DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Upadacitinib After NECS in Vitiligo
Status: NOT_YET_RECRUITING
Conditions: Vitiligo
Interventions: DRUG: Upadacitinib 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease.
Status: COMPLETED
Conditions: Cushing's Disease
Interventions: DRUG: Pasireotide sub-cutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposomes in Combination With GDP in Relapsed/Refractory PTCL
Status: RECRUITING
Conditions: Treatment|Peripheral T-cell Lymphoma
Interventions: DRUG: liposomal mitoxantrone hydrochloride, gemcitabine, dexamethasone, and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Minimally Invasive Thymectomy on the Subsequent Clinical Course of Myasthenia Gravis
Status: UNKNOWN
Conditions: Myasthenia Gravis
Interventions: PROCEDURE: thymectomy (robotic-assisted thoracoscopic, minimally-invasive thymectomy)|PROCEDURE: thymectomy by means of median sternotomy (transsternal)|PROCEDURE: no thymectomy (control)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Ketones and Niacin in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure, Systolic|Ketonemia
Interventions: BIOLOGICAL: Placebo NaCl|BIOLOGICAL: Niacin|BIOLOGICAL: Na-3-OHB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study on Indications of "Bard" PowerPort Isp Implantable Port
Status: COMPLETED
Conditions: Power Port|Image Accuracy
Interventions: DEVICE: "Bard"PowerPort sip Implantable Port|DEVICE: Conventional Port
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stryker Triathlon Total Knee System for Total Knee Arthroplasty Implanted Using ShapeMatch® Cutting Guides: Sub-Study B
Status: COMPLETED
Conditions: Arthroplasties, Replacement, Knee
Interventions: DEVICE: ShapeMatch Cutting Guides with Triathlon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Wound Infiltration for Tracheal Reconstruction
Status: WITHDRAWN
Conditions: Upper Tracheal Resection|Tracheal Reconstruction Surgery
Interventions: PROCEDURE: Superficial cervical plexus block|PROCEDURE: Local wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Placebo|DRUG: RG7774
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIIB033 In Acute Optic Neuritis (AON)
Status: COMPLETED
Conditions: Acute Optic Neuritis
Interventions: BIOLOGICAL: BIIB033 (anti-LINGO-1 mAb)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy in Treating Patients With HIV-Related Primary Central Nervous System Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: methotrexate|DRUG: zidovudine|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Physician Modified Endograft For Complex Aortic Aneurysm Repair
Status: RECRUITING
Conditions: Complex Abdominal Aortic Aneurysm|Juxtarenal Aortic Aneurysm|Pararenal Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor
Status: COMPLETED
Conditions: Carcinoid Tumor|Malignant Carcinoid Syndrome
Interventions: DRUG: Octreotide|DRUG: Placebo|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Sealing Socket Abutment Technique With Immediate Implant in the Mandibular Molars
Status: COMPLETED
Conditions: Soft Tissue Mass
Interventions: DEVICE: Sealing Socket Abutment|DEVICE: cover screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Phase 2 Study of ManNAc in Subjects With GNE Myopathy
Status: COMPLETED
Conditions: GNE Myopathy
Interventions: DRUG: ManNAc|DRUG: ManNAc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Administration on Patients With Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Quality of Life|Food Intolerance|Flare Up|Ulcerative Colitis|Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Trilac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Simplification of Low Level Internal Dosimetry
Status: COMPLETED
Conditions: Exposure to Medical Diagnostic Radiation
Interventions: OTHER: 18-F FDG PET/CT dosimetry scans and measurements|OTHER: Ga-68 PSMA PET/CT dosimetry scans and measurements|OTHER: 68-Ga Dotatate PET/CT dosimetry scans and measurements|OTHER: 99mTc Pertechnetate Thyroid dosimetry scans and measurements|OTHER: 99mTc DMSA(III) Renal dosimetry scans and measurements|OTHER: 99mTc MAG3 Renal dosimetry scans and measurements|OTHER: 99mTc MDP/HDP Bone dosimetry scans and measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Various Formulations of LY900014 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY900014|DRUG: Insulin lispro (Humalog)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vacuum Assisted Closure Versus On-demand Relaparotomy in Patients With Fecal or Diffuse Peritonitis
Status: RECRUITING
Conditions: Fecal Peritonitis|Secondary Peritonitis|Diffuse; Peritonitis
Interventions: PROCEDURE: Vacuum assisted closure|PROCEDURE: Relaparotomy "on demand"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft
Status: COMPLETED
Conditions: Degenerative Osteoarthritis|Post-traumatic; Arthrosis|Rheumatoid Arthritis & Other Inflammatory Polyarthropathies|Rheumatoid Arthritis of Subtalar Joint
Interventions: PROCEDURE: Subtalar Arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Phenylephrine Infusion to Reduce Postoperative Shivering in Lower Segment Caesarean Section
Status: COMPLETED
Conditions: Postoperative Shivering
Interventions: DRUG: Phenylephrine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Gene Editing For Sickle Cell Disease
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Plerixafor|DRUG: Busulfan|DRUG: Gene-modified CD34+ cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study to Look at Fast-acting Insulin Aspart With the Insulin Pump System 'iLet™' in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Fast-acting insulin aspart|DEVICE: iLet™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harvard Atherosclerosis Reversibility Project (HARP)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: pravastatin|DRUG: niacin|DRUG: cholestyramine|DRUG: gemfibrozil|DRUG: fatty acids, omega-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy of Completely Resected Merkel Cell Carcinoma With Immune Checkpoint Blocking Antibodies vs Observation
Status: ACTIVE_NOT_RECRUITING
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin Non-responsiveness and Clopidogrel Endpoint Trial.
Status: COMPLETED
Conditions: Coronary Heart Disease|Angina Pectoris|Atherosclerosis
Interventions: DRUG: aspirin|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synchronization and Desynchronization Between Circadian Rhythms in Patients With Delayed Sleep Phase Syndrome (DSPS)
Status: UNKNOWN
Conditions: Delayed Sleep Phase Syndrome
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) for Prophylaxis of SARS-CoV-2 Infection (COVID-19)
Status: COMPLETED
Conditions: COVID-19|COVID-19 Immunisation
Interventions: BIOLOGICAL: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities
Status: ENROLLING_BY_INVITATION
Conditions: Intellectual Disability|Fragile X Syndrome|Down Syndrome|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of Adults Undergoing Elective Surgery Utilizing Intraoperative Incisional Wound Irrigation
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Intraoperative incisional wound irrigation with povidone-iodine solution|PROCEDURE: Intraoperative incisional wound irrigation with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Primary Mediastinal B-cell Lymphoma (PMBCL)|Mantle Cell Lymphoma (MCL)|Diffuse Large B Cell Lymphoma( DLBCL)
Interventions: BIOLOGICAL: CD19-CAR-NK/T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Status: COMPLETED
Conditions: Traumatic Brain Injury|Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Experimental - COMPASS|BEHAVIORAL: Control - COMPASS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rigid Versus Semirigid Thoracoscopy in Diagnosing Pleural Diseases: a Randomized Study
Status: COMPLETED
Conditions: Pleural Diseases
Interventions: DEVICE: semirigid thoracoscopy|DEVICE: rigid thoracoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants, Ages 2 to <12 Years, With Confirmed or Suspected Bacterial Infection (MK-1986-013)
Status: COMPLETED
Conditions: Gram-Positive Bacterial Infections
Interventions: DRUG: Tedizolid Phosphate (IV)|DRUG: Tedizolid Phosphate (oral suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immuno-inflammation in the Acute Phase of an Ischaemic Cerebral Accident Managed by Decompressive Hemicraniectomy: a Case-control Study
Status: NOT_YET_RECRUITING
Conditions: Ischemic Cerebrovascular Accident
Interventions: PROCEDURE: Decompressive hemicraniectomy|PROCEDURE: neurosurgical operation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients
Status: RECRUITING
Conditions: Lung Transplant|GERD
Interventions: DEVICE: Reflux Band
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GAIN Symptoms: Post-traumatic Headache
Status: RECRUITING
Conditions: Post-Traumatic Headache|Concussion, Mild|MTBI - Mild Traumatic Brain Injury
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation (rTMS)|DEVICE: Sham repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess Subcutaneous Lirentelimab (AK002) in Chronic Spontaneous Urticaria
Status: TERMINATED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Lirentelimab (AK002)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAnagement of Systolic Blood Pressure During Thrombectomy by Endovascular Route for Acute Ischaemic STROKE
Status: RECRUITING
Conditions: Stroke|Embolus Cerebral|Blood Pressure
Interventions: PROCEDURE: Blood pressure management of Systolic Blood Pressure to maintain target range +/- 10 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Cognition in Motor Learning After Stroke
Status: UNKNOWN
Conditions: Stroke Hemorrhagic|Stroke, Ischemic|Cognitive Impairment
Interventions: BEHAVIORAL: Error Augmentation Feedback|BEHAVIORAL: No Error Augmentation Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Literacy for Children With Atopic Dermatitis and Their Caregivers
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: BEHAVIORAL: Nurse instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Dexmedetomidine on Peroperative Shivering Incidence Under Spinal Anesthesia
Status: COMPLETED
Conditions: Perioperative/Postoperative Complications
Interventions: DRUG: Levobupivacaine|DRUG: Dexmedetomidine|DRUG: Dexmedetomidine|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Endometrial Coculture (AECCT)
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: AECC (Autologous endometrial coculture)|OTHER: no endometrial biopsy or Autologous endometrial coculture (AECC) performed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Tramadol HCl/Acetaminophen Compared to Placebo in Treating Acute Low Back Pain
Status: TERMINATED
Conditions: Back Pain|Low Back Pain
Interventions: DRUG: tramadol hydrochloride , acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Expanded Cohort Trial of Bortezomib and Sorafenib in Advanced Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: bortezomib|DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Dexmedetomidine Versus Intranasal Midazolam for MRI In Pediatrics
Status: COMPLETED
Conditions: Dexmedetomidine|Midazolam|MRI|Pediatrics
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison Between Right and Left Ventricular Systolic Dysfunction as a Risk Factors for Aki in Critical Care Patients
Status: UNKNOWN
Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: DIAGNOSTIC_TEST: Serum urea and creatinine and the calculated e GFR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Motion Syros: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness
Status: COMPLETED
Conditions: Motion Sickness
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Block Versus Trans Muscular Quadratus Lumborum Block in Patients Undergoing Correction of Hip Dysplasia
Status: RECRUITING
Conditions: Hip Dysplasia
Interventions: PROCEDURE: Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block|PROCEDURE: trans muscular quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Inflammation|Surgery
Interventions: DRUG: Mapracorat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Furcal Perforation Repair in Primary Molars With MTA Versus Bioceramics (A Randomized Clinical Trial)
Status: COMPLETED
Conditions: Iatrogenic Perforation of Primary Molars
Interventions: OTHER: Bioceramics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ciclesonide on Quality of Life in Patients With Moderate Persistent Asthma (21 to 65 y) (BY9010/AR-101)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Could the Therapy With Inositol Affect the Cardiovascular Risk in PCOS Women? Results of a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Placebo|DRUG: Inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
Status: COMPLETED
Conditions: Photoaging|Wrinkle|Skin Laxity
Interventions: PROCEDURE: Hybrid Fractional Laser|OTHER: Facial Cleanser|OTHER: Facial Moisturizer|OTHER: Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of T-PRED(TM) Compared to Pred Forte(R) II
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: T-Pred|DRUG: Pred Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serratus Anterior Plane Block With and Without Adjuvants in Video-assisted Thoracoscopy
Status: UNKNOWN
Conditions: Post Operative Pain, Acute
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution|DRUG: Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 150 mg|DRUG: Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 150 mg, Buprenorphine 300 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Initial Resuscitation With Albumin in Hemorrhagic Shock to Reduce Positive Fluid Balance
Status: NOT_YET_RECRUITING
Conditions: Bleeding|Massive Hemorrhage|Massive Transfusion Protocol
Interventions: DRUG: Albumin solution|DRUG: Balanced crystalloid solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Graft Versus Acellular Dermal Matrix in Preservation of Buccal Plate of Bone
Status: COMPLETED
Conditions: Comparative Study
Interventions: COMBINATION_PRODUCT: Acellular Dermal Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Open Surgery for Lesions Originating in the Paracaval Portion of the Caudate Lobe
Status: UNKNOWN
Conditions: Paracaval Portion
Interventions: PROCEDURE: laparoscopic surgery|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Utilization of Buprenorphine in the Emergency Room to Treat Clinical Opioid Withdrawal
Status: COMPLETED
Conditions: Drug Overdose|Opioid Withdrawal|Opioid-use Disorder
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School
Status: RECRUITING
Conditions: Alcohol Use, Unspecified
Interventions: BEHAVIORAL: Most hoped for future self|BEHAVIORAL: Most feared future self|BEHAVIORAL: Control (trip to zoo)|BEHAVIORAL: Balanced future self
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy in Treating Patients With Previously Treated Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: CpG oligodeoxynucleotide|BIOLOGICAL: HER-2/neu peptide vaccine|BIOLOGICAL: MUC-1 peptide vaccine|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: sargramostim|OTHER: immunoenzyme technique|OTHER: immunologic technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Assessment Tools in Predicting Treatment Success of Cimzia in Rheumatoid Arthritis Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab Pegol (CZP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of a Polyphenol-rich Preparation as Support for Oncology Patients Undergoing Gastrointestinal Tumor Resection
Status: RECRUITING
Conditions: Immunomodulation
Interventions: DIETARY_SUPPLEMENT: Nutridrink Skin Repair with a mixture of plant extracts rich in polyphenolic compounds|DIETARY_SUPPLEMENT: Nutridrink Skin Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Colon Cancer|Rectal Cancer
Interventions: PROCEDURE: Single-incision Laparoscopic Surgery|PROCEDURE: Conventional Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utidelone Combined With Bevacizumab in the Treatment of ≥ 2 Lines of HER-2 Negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER-2 Negative Breast Cancer
Interventions: DRUG: Utidelone Combined with Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Corneal Collagen Crosslinking Versus Transepithelial Corneal Crosslinking by Iontophoresis of Riboflavin
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: iontophoresis of riboflavin|PROCEDURE: epithelium-off|PROCEDURE: Corneal collagen crosslinking|DEVICE: galvanizator, Potok-1|DRUG: Dextralink|DRUG: Riboflavin 0,1%|DEVICE: UFalink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Phosphatidylcholine in a Patient With Methionine Adenosyltransferase Deficiency
Status: COMPLETED
Conditions: Methionine Adenosyltransferase Deficiency|Metabolism, Inborn Errors
Interventions: DRUG: phosphatidylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Subjects With Neuropathic Pain From PHN Who Have Had an Inadequate Response to Gabapentin Treatment
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: GEn 1200mg/day|DRUG: GEn 3600mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Dysphagia|Non-Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: Palifermin|DRUG: Placebo|RADIATION: Radiotherapy|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tildrakizumab in Difficult-to-treat Areas in Psoriasis
Status: RECRUITING
Conditions: Psoriasis Palmaris|Psoriasis Genital|Psoriasis of Scalp|Psoriasis Plantaris|Psoriasis Nail
Interventions: OTHER: Psoriasis clinical assessments|OTHER: Quality of life evaluation|OTHER: Satisfaction assessment|OTHER: Pruritus evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Newborn Heart Rate as a Catalyst for Improved Survival
Status: COMPLETED
Conditions: Stillbirth|Neonatal Respiratory Depression|Neonatal Bradycardia|Neonatal Resuscitation
Interventions: OTHER: Epoch 2: HBB with NeoBeat|OTHER: Epoch 3: HR-guided HBB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: the Effect of the CALIGALOC Orthosis on Standing and Walking of Hemiparetic Patients With Ankle Varus
Status: UNKNOWN
Conditions: Hemiparesis|Varus Deformity of Equine Carpus
Interventions: DEVICE: Caligaloc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection Snoreplasty and Oropharyngeal Exercises
Status: UNKNOWN
Conditions: Snoring|Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Injection Snoreplasty|OTHER: Oropharyngeal Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization.
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: nesiritide|DRUG: usual long term cardiac medications|DRUG: nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Erythropoietin on the Incidence of Acute Kidney Injury Following Complex Valvular Heart Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: EPO group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasm Metastasis
Interventions: DRUG: AVE0005 (aflibercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients
Status: RECRUITING
Conditions: Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: immunonutrition|BEHAVIORAL: oral chlorhexidine decontamination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Repetitive Transcranial Magnetic Stimulation Therapy on Lower Extremity Motor Development in Stroke Patients
Status: COMPLETED
Conditions: Neurological Rehabilitation|Stroke|Lower Extremity Problem|Quality of Life
Interventions: DEVICE: Low Frequency rTMS Protocol|DEVICE: Intermittent Theta Burst Stimulation (iTBS) Protocol|DEVICE: Sham rTMS Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of Cisplatin to Adjuvant Chemotherapy for Early Stage Breast Cancer in High-Risk Women
Status: UNKNOWN
Conditions: Tubular Breast Cancer|Mucinous Breast Cancer|Invasive Duct Carcinoma of Breast
Interventions: DRUG: Paclitaxel, Cisplatin|DRUG: EC to docetaxel or paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Sleeve Pouch Versus Relatively Wide Pouch With Plication
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: PROCEDURE: sleeve with plication|PROCEDURE: sleeve without plication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3-Year Follow-up Study of Randomized Controlled Trial.
Status: COMPLETED
Conditions: Gastro -Oesophagal Reflux
Interventions: PROCEDURE: open fundoplication|PROCEDURE: laparoscopic fundopliaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-line Treatment With RC48 Plus Tislelizumab and S-1(RCTS) in Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Gastric Cancer
Interventions: DRUG: Disitamab vedotin|DRUG: Tislelizumab|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK618334 Repeat Dose Study
Status: COMPLETED
Conditions: Substance Dependence
Interventions: DRUG: GSK618334 Low Dose|DRUG: GSK618334 PET subjects|DRUG: GSK618334 Medium Dose|DRUG: GSK618334 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of Fallot
Status: UNKNOWN
Conditions: Congenital Heart Disease|Fallot Tetralogy|Ventricular Arrythmia|Pulmonary Valve Regurgitation
Interventions: PROCEDURE: Programmed ventricular stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of TopotectTM (Dexrazoxane) for Accidental Extravasation of Anthracyclines
Status: COMPLETED
Conditions: Anthracycline Extravasation
Interventions: DRUG: Dexrazoxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild Encephalopathy in the Newborn Treated With Darbepoetin
Status: COMPLETED
Conditions: Neonatal Encephalopathy|Hypoxic-Ischemic Encephalopathy Mild
Interventions: DRUG: Darbepoetin Alfa|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-Regulatory Cell Kinetics, Stem Cell Transplantation, REGKINE
Status: TERMINATED
Conditions: Leukemia|Cancer|Lymphoma|Lymphoma, Hodgkin|Lymphoma, Non-Hodgkin
Interventions: DRUG: Ara C|DRUG: Mesna|DRUG: Cyclophosphamide|RADIATION: TBI-Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elevation of the Fetal Buttocks Prior to External Cephalic Version
Status: TERMINATED
Conditions: Breech Presentation|External Cephalic Version
Interventions: DEVICE: Fetal Pillow insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Combination With Iressa in Previously Treated Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Carcinoma
Interventions: DRUG: ZD 1839|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique
Status: COMPLETED
Conditions: Trauma|Orthopedic Surgery Complications
Interventions: DEVICE: Use it to treatment bone nonunion (Ilzarov)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Deferred Aortic Valve Replacement in Patients With Moderate Aortic Stenosis and Mitral Regurgitation
Status: RECRUITING
Conditions: Aortic Valve Replacement in Patients With Moderate Aortic Stenosis Combined With Mitral Regurgitation
Interventions: PROCEDURE: Transcatheter or surgical aortic valve replacement with or without transcatheter or surgical mitral valve repair/replacement|PROCEDURE: Deferred treatment, with intervention once AVA is ≤1.0 cm2 or if concomitant mitral regurgitation meets an indication for intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine
Status: COMPLETED
Conditions: Prediabetic State|Impaired Glucose Tolerance|Insulin Resistance
Interventions: DRUG: Linagliptin / Metformin Oral Tablet|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Immunogenicity of Co-administering Human Papillomavirus (HPV) Vaccine With Other Vaccines in Healthy Female Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Boostrix ® Polio|BIOLOGICAL: GSK Biologicals' HPV-16/18 L1 AS04 vaccine (Cervarix TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Online Training of Empathic Attunement to Affect
Status: COMPLETED
Conditions: Empathy
Interventions: BEHAVIORAL: Empathic Attunement to Affect Training|BEHAVIORAL: Compassion Training|BEHAVIORAL: Focusing Oriented Therapy Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Use of Master Caution Garment for Continuous Monitoring for Arrhythmia Detection
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DEVICE: Master Caution Garment|DEVICE: ECG gel electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: QUILT-3.034: Non-Myeloablative TCRa/b Deplete Haplo HSCT With Post ALT-803 for AML
Status: WITHDRAWN
Conditions: High-Risk Acute Myeloid Leukemia|Treatment-Related Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: ALT-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-operative Rectus Sheath Block Versus TEA Abdominal Surgeries
Status: COMPLETED
Conditions: Abdominal Cancer
Interventions: PROCEDURE: Thoracic epidural block (TEA)|PROCEDURE: Rectus sheath block (RSB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease|Ulcerative Colitis
Interventions: DRUG: KleanLyte|DRUG: Bi-PegLyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vagus Nerve-preserving RADG and Conventional RADG for AGC
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: Vagus nerve-preserving Robot-assisted Gastrectomy|PROCEDURE: Conventional Robot-assisted Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder
Status: RECRUITING
Conditions: Dementia With Lewy Bodies|Parkinson Disease|REM Sleep Behavior Disorder
Interventions: DIAGNOSTIC_TEST: Skin biopsy|DIAGNOSTIC_TEST: Speech testing|DIAGNOSTIC_TEST: Ultra high field 7T MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intramuscular Ketamine for Suicidal Ideation
Status: WITHDRAWN
Conditions: Suicidal Ideation
Interventions: DRUG: Ketamine (Ketalar)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Therapeutic Effects of VR and VR + GnRHa in the Treatment of Cesarean Scar Diverticula
Status: UNKNOWN
Conditions: Cesarean Scar Diverticula
Interventions: DRUG: GnRHa|PROCEDURE: Vaginal repair of CSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery (SFA) and Proximal Popliteal Artery (PPA)
Status: COMPLETED
Conditions: Femoral Artery Stenosis|Popliteal Artery Stenosis|Femoral Artery Occlusion|Popliteal Artery Occlusion
Interventions: DEVICE: Drug-Coated Balloon (DCB)|DEVICE: PTA Balloon: Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Optimal Dose of VM-1500 in Comparison to Efavirenz Added to Standard-of-care Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: VM-1500|DRUG: Efavirenz|DRUG: Antiretroviral therapy (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Storybook Reading in Individuals With Down Syndrome
Status: TERMINATED
Conditions: Down Syndrome|Augmentative and Alternative Communication
Interventions: DEVICE: AAC Technology - Standard of Care|DEVICE: AAC Technology - non-optimal integrated arrangement|DEVICE: AAC Technology - non-optimal integrated arrangement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Double Blind Open Label Comparator Study to Compare Treatments in 4 to 11 Year Old Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Propionate MDPI|DRUG: Fluticasone Propionate/Salmeterol MDPI|DRUG: Fluticasone propionate/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Benefits of High-intensity Interval Training for Individuals With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Exercise Training
Interventions: OTHER: High Intensity Interval Training|OTHER: Continuous Moderate Intensity Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on Expandion of MILs From NSCLC and SCLC Patients and Infusion With Pembrolizumab
Status: WITHDRAWN
Conditions: SCLC|NSCLC
Interventions: COMBINATION_PRODUCT: MILs™ in Combination with Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II of High-dose Therapy in Elderly Patients With Relapsed Aggressive NHL or Resistant to First Line Therapy
Status: UNKNOWN
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: R-DHAP/R-ICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability Study of SHAPE in IA, IB or IIA Cutaneous T-cell Lymphoma
Status: UNKNOWN
Conditions: Cutaneous T-Cell Lymphoma (CTCL)
Interventions: DRUG: SHAPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Text Messages to Improve Oral Chemotherapy for Adolescents and Young Adults With Acute Lymphoblastic Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: OTHER: High Intensity|OTHER: No Text Messagings|OTHER: Low Intensity Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER