pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: HER2 Targeted Molecular Imaging in mBC Using 68Ga-ABS011
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-NOTA-ABSCINT-HER2 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimal Protamine Dosing for Heparin Reversal Following Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Coagulation; Intravascular
Interventions: DRUG: Protamine fixed dose|DRUG: Protamine ratio dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Continuous Infusions of HNO (Nitroxyl) Donor in Patients With Heart Failure and Impaired Systolic Function
Status: COMPLETED
Conditions: Heart Failure|Cardiac Failure|Reduced Ventricular Ejection Fraction
Interventions: DRUG: HNO Donor|DRUG: Nitroglycerin (NTG)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Higher Versus Standard Dose of Amoxicillin-clavulanate in Pediatric PBB
Status: UNKNOWN
Conditions: Protracted Bacterial Bronchitis
Interventions: DRUG: Amoxicillin-Clavulanate 200 Mg-28.5 Mg Oral dry suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin
Status: COMPLETED
Conditions: Soft Contact Lenses|Myopia
Interventions: DEVICE: Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye|DEVICE: Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Study to Evaluate Efficacy, Tolerability, Safety of Derinat
Status: UNKNOWN
Conditions: Respiratory Infections in Children
Interventions: DRUG: Derinat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Anti-viral Activity, Safety, Tolerability and Pharmacokinetics of TMC435350 in Participants Infected With Hepatitis C-Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurodynamic Interventions for Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Physical Therapy|OTHER: Physical Therapy plus Neurodynamic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Analgesia in Multiparas Undergoing Induction of Labour
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: bupivacaine, fentanyl|DRUG: preservative free saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile Health Intervention (Support-moms) in Antenatal Care to Improve Maternal Health in Uganda
Status: RECRUITING
Conditions: Maternal Health
Interventions: BEHAVIORAL: Support-Moms|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Bronchodilators|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study of a Virosomal Vaccine Against Recurrent Vulvovaginal Candida Infection
Status: COMPLETED
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: BIOLOGICAL: PEV7C1|BIOLOGICAL: PEV7C9|BIOLOGICAL: PEV7B2|BIOLOGICAL: PEV7B1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
Status: RECRUITING
Conditions: Tremor Associated With Tremor Dominant Parkinson's Disease
Interventions: DEVICE: Unilateral thalamotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial of a Nutritional Supplement in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DIETARY_SUPPLEMENT: Resveratrol with Glucose, and Malate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RSA Study of Sirius Stem and Exceed Cup
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Optivac|DEVICE: Optipac|DEVICE: Arcom (Exceed cup)|DEVICE: E1 (Exceed cup)|DEVICE: Sirius stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Red Raspberry Polyphenols on Gut Microbiome
Status: COMPLETED
Conditions: Healthy Subjects|Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: Raspberry and fructooligosaccharide|DIETARY_SUPPLEMENT: Raspberry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Neural Response to Inflammatory Challenge in Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BIOLOGICAL: LPS|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia
Status: RECRUITING
Conditions: Preeclampsia
Interventions: DRUG: Metformin ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Cognitive-Affective Training for Opioid Use Disorder- A Phase 2 RCT
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DEVICE: MORE-VR|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deferiprone on Oxidative-Stress and Iron-Overload in Low Risk Transfusion-Dependent MDS Patients
Status: COMPLETED
Conditions: Myelodysplastic Syndrome With Low-grade Lesions|Iron Overload Due to Repeated Red Blood Cell Transfusions
Interventions: DRUG: Deferiprone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Cytokine-induced Killer Cells Combined Chemotherapy in Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Cytokine-induced Killer Cells|DRUG: Tegafur-Gimeracil-Oteracil Potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Suicide Prevention Strategies for Pediatric Primary Care
Status: NOT_YET_RECRUITING
Conditions: Suicidal Ideation|Suicidal and Self-injurious Behavior|Depression
Interventions: BEHAVIORAL: iCHART/cASAP|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Constipation
Status: NOT_YET_RECRUITING
Conditions: Constipation
Interventions: OTHER: Aerobic Exercise|OTHER: Abdominal Massage|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Education and Basic Body Awareness Therapy in Hip Osteoarthritis: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: OTHER: Patient Education and Basic Body Awareness Therapy|BEHAVIORAL: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Oral Eligen® B12 in Subjects With Low Serum Cobalamin
Status: COMPLETED
Conditions: Vitamin B 12 Deficiency
Interventions: OTHER: Vitamin B12 (cyanocobalamin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Video-Assisted Training on Upper Extremity Problems and Functions in Patients Undergoing Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Repair
Interventions: OTHER: video-assisted training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a Multimodal Exercise Program for Children With ASD
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Asperger Syndrome
Interventions: BEHAVIORAL: High-intensity exercise|DEVICE: Wearable glove and arm sleeve device to measure movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: metformin HCl (Cidophage®; CID,Cairo, Egypt), CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt),Cairo, Egypt)|PROCEDURE: Laparoscopic ovarian diathermy (LOD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of MET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: OTHER: MRI & PET fusion|OTHER: MRI+T1C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Brain Stimulation Using Transcranial Direct Current Stimulation Simulation in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of the First Conversational Agent for Smoking Cessation (QuitBot)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Immediate access to novel messaging program intervention|BEHAVIORAL: Immediate access to standard of care messaging program intervention|BEHAVIORAL: Delayed access to novel novel messaging program intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Protein Bar for Physically Active People
Status: COMPLETED
Conditions: Muscle Mass|Inflammation|Regeneration Muscle
Interventions: DIETARY_SUPPLEMENT: DrRip - high protein, high fibre and creatine load|DIETARY_SUPPLEMENT: Voltage energy bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Cancer
Interventions: DRUG: capecitabine|DRUG: lapatinib ditosylate|OTHER: circulating tumor cell analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Macitentan Use in an Idiopathic Pulmonary Fibrosis Clinical Study
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: ACT-064992 (macitentan)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewing Radiographs
Status: RECRUITING
Conditions: Dental Caries|Patient Compliance
Interventions: DEVICE: Near infra red imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients
Status: RECRUITING
Conditions: Dry Eye|Dry Eye Syndromes
Interventions: DRUG: TJO-083|DRUG: Diquafosol ophthalmic sodium solution 3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Defining the Operating Characteristics of NIRS in the Diagnosis of Pediatric Traumatic Intracranial Hemorrhage
Status: ACTIVE_NOT_RECRUITING
Conditions: Craniocerebral Injuries|Head Injuries|Head Injury, Minor|Head Trauma|Traumatic Brain Injury|Traumatic Brain Hemorrhage|Hematoma of Head|Intracranial Hemorrhages
Interventions: DEVICE: InfraScanner 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Ureteropelvic Junction Obstruction in Early Childhood: Comparison of Surgical Therapy and Surveillance. A Prospective, Randomized, Controlled Multi-Center Study
Status: UNKNOWN
Conditions: Unilateral Ureteropelvic Junction Obstruction
Interventions: PROCEDURE: Pyeloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Leuprolide Acetate Injectable Suspension in the Treatment of Central Precocious Puberty
Status: COMPLETED
Conditions: Precocious Puberty, Central
Interventions: DRUG: Leuprolide Acetate 45 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Rotator Cuff Fatigue.
Status: COMPLETED
Conditions: Asymptomatic Condition
Interventions: OTHER: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IB3,IIA2)
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: OTHER: Total Laparoscopic or Robotic Radical Hysterectomy|OTHER: Total Abdominal Radical Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Pain and Oral Wound Healing After Third Molar Surgery
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938/ATCC PTA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers
Status: TERMINATED
Conditions: Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer
Interventions: DRUG: KITE-439|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An INtervention TO Improve MOBility of Older Hospitalized Patients
Status: RECRUITING
Conditions: Hospital Mobility|Mobility Limitation|Life-Space|Functional Status|Hospital-Acquired Condition|Muscle Atrophy or Weakness|Sarcopenia|Iatrogenic Disease
Interventions: BEHAVIORAL: INTOMOB intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral vs Intravenous and Proton Pump Inhibitor (PPI）for Peptic Ulcer Bleeding (PUB)
Status: WITHDRAWN
Conditions: Upper Gastrointestinal Bleeding
Interventions: DRUG: lansoprazole|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DAW1033B2 in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DRUG: Placebo oral capsule|DRUG: DAW1033B2 oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps|Sinusitis
Interventions: PROCEDURE: Middle turbinate resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study Evaluating the Effectiveness of Endo.Angel in Improving the Quality of Colonoscopy
Status: UNKNOWN
Conditions: Adenoma Detection Rate
Interventions: DIAGNOSTIC_TEST: colonoscopy with assistance of Endo.Angel|DIAGNOSTIC_TEST: colonoscopy without assistance of Endo.Angel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Submucosal Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia (HHT)
Interventions: DRUG: Submucosal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Market Research - Acceptability Trial for a New PKU Amino Acid Based Protein Substitute
Status: COMPLETED
Conditions: PKU|Phenylketonurias|Inborn Errors of Metabolism|Metabolic Disease
Interventions: DIETARY_SUPPLEMENT: Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindfulness Training Plus Oxytocin Effects on Smoking Behavior
Status: TERMINATED
Conditions: Smoking|Smoking Cessation
Interventions: DRUG: Oxytocin|BEHAVIORAL: Mindfulness|DRUG: Saline Solution|BEHAVIORAL: Sham mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trials of Effects of Time Restricted Eating on Health Parameters in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Time Restricted Feeding|Overweight and Obesity|Inflammation|Hypercholesterolemia|Hypertension|Hyperglycemia|Antioxidative Stress|Metabolic Syndrome|Microbial Colonization
Interventions: OTHER: Effects of calorie restriction and time-restricted eating on human health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical and Radiographic Evaluation of Revascularization of Immature Anterior Permanent Teeth Using Concentrated Growth Factor (CGF) Versus Blood Clot (BC)
Status: NOT_YET_RECRUITING
Conditions: Revascularization
Interventions: PROCEDURE: concentrated growth factors in open apex|PROCEDURE: Blood Clot (BC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ULTRATRACE Iobenguane I 131 in Patients With Malignant Pheochromocytoma, Paraganglioma, or Metastatic Carcinoid
Status: COMPLETED
Conditions: Pheochromocytoma|Paraganglioma|Carcinoid
Interventions: DRUG: Ultratrace iobenguane I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phenotyping Genetic Risk for Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Genetics
Interventions: OTHER: 75g glucose beverage (Glucola, Trutol, or similar brand)|OTHER: DXA, whole body
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Malignant Vertebral Fractures With Percutaneous Balloon Kyphoplasty.
Status: TERMINATED
Conditions: Vertebral Fracture|Multiple Myeloma|Osteolytic Metastases
Interventions: DEVICE: balloon kyphoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Fish-oil Fatty Acids on Postprandial Vascular Reactivity
Status: COMPLETED
Conditions: Cardiovascular Physiological Phenomena|Endothelial Nitric Oxide Synthase|Eicosapentaenoic Acid|Docosahexaenoic Acid (All-Z Isomer)
Interventions: DIETARY_SUPPLEMENT: EPA|DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Regimen of Bendamustine-Debulking Followed by CAL-101 and GA101-Induction and -Maintenance in CLL (CLL2-BCG)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leucemia
Interventions: DRUG: Bendamustine|DRUG: GA101|DRUG: CAL-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Encapsulated Probiotic Bifidobacterium Infantis 35624 in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Bifidobacterium infantis 35624
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: RADIATION: proton radiation|PROCEDURE: surgery (wide local excision; limb preservation surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Decision-Making Tool for Opioid Prescribing After Ambulatory Hand Surgery in Veterans
Status: COMPLETED
Conditions: Opioid Use|Surgery
Interventions: BEHAVIORAL: Educational Shared-Decision Making Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Synergy Disc To Anterior Cervical Discectomy and Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Degenerative Disc Disease
Interventions: DEVICE: Anterior Cervical Discectomy & Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Sjogren's Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome|Autoimmune Diseases
Interventions: BIOLOGICAL: Assigned Interventions CD19/BCMA CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Vaginal Surgery VS Autologous Tissue in Pelvic Floor Repair
Status: RECRUITING
Conditions: Vaginal Vault Prolapse
Interventions: PROCEDURE: vNOTES suspension with autologous tissue|PROCEDURE: Vaginal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery
Status: RECRUITING
Conditions: Colorectal Disorders|Prolapse|Prolapse Rectal|Prolapse Genital|Prolapse Pelvic|Rectocele|Prolapse Uterus|Cystocele|Enterocele|Prolapse Bladder|Prolapse; Cervix
Interventions: PROCEDURE: Minimal invasive abdominal prolapse surgery using Polypropylene mesh|PROCEDURE: Minimal invasive abdominal prolapse surgery using OviTex 1S permanent mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training and Hepatic Metabolism in Overweight/Obese Adolescent
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome X|Lipid Metabolism Disorders|Body Composition, Beneficial|Mental Health Wellness 1
Interventions: BEHAVIORAL: Low physical activity program|BEHAVIORAL: High physical activity program|BEHAVIORAL: Low and High physical activity program|BEHAVIORAL: Conventional physical activity program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety, Tolerability, and Treatment Response Study of Paliperidone Palmitate Administered to Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
Status: RECRUITING
Conditions: Vasospasm, Intracranial|Subarachnoid Hemorrhage
Interventions: DEVICE: Extraventricular Drain|DEVICE: Lumbar Drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Buddhist Monks in Providing Cognitive Behavior Therapy
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: Cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How the Body Processes the Study Medicine Called PF-07923568 in People With Loss of Kidney Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Drug: PF-07923568
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcome of the Anterior Subcutaneous Internal Fixator (INFIX) for Pelvic Ring Disruptions
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Fracture
Interventions: PROCEDURE: anterior subcutaneous internal fixator ( INFIX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Feasibility Study of the Pilot Post-primary Active School Flag (PPASF) Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity|Health Behavior|Health Knowledge, Attitudes, Practice|Educational Problems
Interventions: BEHAVIORAL: Active School Flag Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: MCT|DRUG: Clazakizumab|DRUG: Broncho-Vaxom|DRUG: Imatinib Mesylate|DRUG: Cavosonstat|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy of Cinacalcet vs Traditional Vitamin D for Secondary Hyperparathyroidism (SHPT) Among Subjects Undergoing Hemodialysis
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary
Interventions: DRUG: Traditional Vitamin D Therapy|DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMS European Long-Term Study
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Habitual Diet and Avocado Trial
Status: COMPLETED
Conditions: Intra-abdominal Fat|Metabolic Syndrome|High Cholesterol|Triglycerides High|Diet Habit|High Blood Sugar|Liver Fat|Dietary Modification|HDL Cholesterol, Low Serum|Cardiovascular Diseases|High Density Lipoprotein Deficiency|Low-density-lipoprotein-type|Cardiovascular Risk Factor|Diabetes
Interventions: OTHER: Intervention Daily Avocado
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Antipruritic Effect of PAC-14028 Cream in Skin Pruritus
Status: COMPLETED
Conditions: Skin Pruritus
Interventions: DRUG: PAC-14028|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Type I Collagen Fragments in the GCF and Saliva During OTM
Status: UNKNOWN
Conditions: Collagen Degeneration
Interventions: OTHER: Biological measuring of collagen fragments biomarker during orthodontic tooth movement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Liver Cancer
Interventions: DRUG: PD1/PDL1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Assess the Effects of Vorinostat (MK0683, SAHA) in Patients With Advanced Cancer (0683-070)(COMPLETED)
Status: COMPLETED
Conditions: Advanced Cancer Relapsed|Advanced Cancer Refractory
Interventions: DRUG: vorinostat|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Digoxin|DRUG: Rosuvastatin|DRUG: Digoxin, Furosemide, Metformin hydrochloride, Rosuvastatin|DRUG: Digoxin, Furosemide, Metformin hydrochloride, Rosuvastatin|DRUG: Metformin hydrochloride|DRUG: Digoxin, Furosemide, Metformin hydrochloride, Rosuvastatin|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride in Preventing Cancer in Patients With Precancerous Lesions of the Lung
Status: TERMINATED
Conditions: Dysplasia|Metaplasia|Pulmonary Precancerous Condition
Interventions: DRUG: Erlotinib Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Small Doses of Pituitrin Versus Norepinephrine for the Management of Vasoplegic Syndrome in Patients After Cardiac Surgery
Status: UNKNOWN
Conditions: Postoperative Vasoplegic Syndrome
Interventions: DRUG: Pituitrin infusion|DRUG: Norepinephrine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients
Status: COMPLETED
Conditions: Sickle Cell Disease (SCD)
Interventions: DRUG: crizanlizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of I Line FOLFOX + Panitumumab vs 5FU + Panitumumab in RAS and BRAF WT Metastatic Colorectal Cancer Elderly Patients
Status: UNKNOWN
Conditions: Elderly Metastatic Colorectal Cancer Patients
Interventions: DRUG: 5-fluorouracil|DRUG: oxaliplatin|DRUG: l-leucovorin|DRUG: panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Dosimetry, Metabolism, Safety, Tolerability and Positron Emission Tomography/Computed Tomography (PET/CT) Imaging With BAY 85-8050 in Healthy Volunteers and Patients
Status: COMPLETED
Conditions: Neoplasm
Interventions: DRUG: F-18 (BAY85-8050)|DRUG: F-18 (BAY85-8050)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Whole Abdominal Intensity Modulated Radiotherapy (IMRT) for High Risk Stage FIGO III Patients With Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: RADIATION: whole abdomen irradiation using IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
Status: UNKNOWN
Conditions: Maxillofacial Bone Defects|Alveolar Bone Atrophy|Jaw Fractures|Maxillofacial Bone Deformities|Bone Neoplasm, Benign|Disorders of Teeth and Jaw
Interventions: DEVICE: Gene-activated matrix "Nucleostim"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Atazanavir in Special Populations
Status: COMPLETED
Conditions: HIV/AIDS|Tuberculosis
Interventions: DRUG: Atazanavir 300mg/ Ritonavir 100 mg once daily|DRUG: Atazanavir 250 mg / ritonavir 80 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impulsivity and Stimulant Administration
Status: COMPLETED
Conditions: Cocaine Dependence|Impulsivity
Interventions: DRUG: cocaine hydrochloride|DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Study of Physical Activity Rewards After Knee Surgery
Status: COMPLETED
Conditions: Osteoarthritis|Degenerative Joint Disease
Interventions: BEHAVIORAL: Motivational Interviewing (MI)|OTHER: Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Oral Verapamil and Oral Diltiazim on Reduction of Intraoperative Bleeding During Endoscopic Sinus Surgery Under General Anesthesia
Status: UNKNOWN
Conditions: Verapamil|Diltiazim|FESS
Interventions: DRUG: Verapamil|DRUG: Diltiazem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1)
Status: UNKNOWN
Conditions: Pleural Mesothelioma|Peritoneal Mesothelioma
Interventions: DRUG: tremelimumab plus MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children ( DTaP/DT )
Status: NOT_YET_RECRUITING
Conditions: Vaccine Reaction
Interventions: BIOLOGICAL: vaccinate with DTaP|BIOLOGICAL: vaccinate with DT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stratification of Presymptomatic Amyotrophic Lateral Sclerosis: the Development of Novel Imaging Biomarkers
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Neuroimaging and electrophysiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Three Dimensional Versus Two Dimensional Echocardiography in Assessment of Severity and Scoring of Rheumatic Mitral Stenosis.
Status: UNKNOWN
Conditions: Mitral Valve Stenosis
Interventions: OTHER: 2D Echocardiography|OTHER: 3D Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma After Radical Hepatectomy
Status: COMPLETED
Conditions: Hepatic Carcinoma
Interventions: DRUG: Huaier Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Drug-drug Interactions Between HEC585 and Pirfenidone or Nintedanib in Healthy Volunteers
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: HEC585|DRUG: Pirfenidone|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SAR3419 Administered Weekly in Patients With Relapsed/Refractory CD19-positive B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Non-Hodgkin
Interventions: DRUG: SAR3419
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Basal Bolus|DRUG: Metformin and Sitagliptin|DRUG: Glargine|DRUG: Glargine 50%|DRUG: Glargine 80%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients
Status: RECRUITING
Conditions: Post-stroke Cognitive Impairment
Interventions: DRUG: Edaravone dexborneol sublingual tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Bezafibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: PBC
Interventions: DRUG: Bezafibrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Urethrocutaneous Fistula With and Without Caudal Epidural Block
Status: COMPLETED
Conditions: Distal Hypospadias
Interventions: DRUG: Ropivacaine|DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Ganaxolone|DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restylane + Lidocaine and Restylane Lyft for the Treatment of Nasolabial Folds
Status: COMPLETED
Conditions: Wrinkles Such as Nasolabial Folds
Interventions: DEVICE: Restylane + Lidocaine|DEVICE: Restylane® Lyft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of SHR-1918 in Patients With Hyperlipidemic
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipidemic
Interventions: DRUG: SHR-1918|DRUG: SHR-1918 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Normal Saline vs Hypertonic Saline in the Treatment of Bronchiolitis
Status: COMPLETED
Conditions: Length of Hospital Stay
Interventions: OTHER: Normal saline|OTHER: Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Incisionless Operating Platform as a Primary Treatment for Obesity vs. Diet-Exercise Alone
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: g-CathTM EZ Suture Anchor Delivery Catheter|OTHER: Diet and Exercise Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-Centre Trial of TKI Redifferentiation Therapy in Patients With RAIR Thyroid Cancer (I-FIRST Study)
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: Dabrafenib 75 MG|DRUG: Trametinib 2 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Limited Food Effect Study of Gabapentin 800 mg Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin 800 mg tablets, single dose (1 tablet)|DRUG: NEURONTIN® 400 mg capsules, single dose (2 capsules)|DRUG: Gabapentin 800 mg tablets, single dose (1 tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Epidermal Growth Factor Receptor|Leptomeningeal Metastasis
Interventions: DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ABCC6 Deficiency Causing PXE
Status: ACTIVE_NOT_RECRUITING
Conditions: ATP-Binding Cassette Subfamily C Member 6 Deficiency|Pseudoxanthoma Elasticum|Generalized Arterial Calcification of Infancy
Interventions: DRUG: INZ-701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Therapy on Nausea and Pain for Autologous Stem Cell
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin Lymphoma|Hodgkin Lymphoma
Interventions: OTHER: Music Therapy|OTHER: No music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Whole Body Vibration in Parkinson's Disease Symptoms
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Whole body Vibration|OTHER: Habitual Therapy|DEVICE: Placebo whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
Status: UNKNOWN
Conditions: Cannabis Use Disorder|Cannabis Dependence
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo Oral Tablet|OTHER: Magnetic Resonance Imaging|OTHER: Neurocognitive measures|OTHER: Neuro-inflammatory measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Study
Status: COMPLETED
Conditions: Lesion Skin|Seborrheic Keratosis
Interventions: DEVICE: Nano-Pulse Stimulation (NPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balancing Treatment Outcomes and Medication Burden Among Patients With Symptomatic Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: BEHAVIORAL: IVR Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Posterolateral Structure of Knee Joint Under Arthroscopy
Status: UNKNOWN
Conditions: the Posterolateral Structure of the Knee Joint|Arthroscopy|Anatomical Reconstruction
Interventions: PROCEDURE: Arthroscopic anatomical reconstruction of the posterolateral structure of the knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colon Cancer|Rectal Cancer
Interventions: DRUG: TAS-102, oxaliplatin, irinotecan with bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT