pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Different Length of Time for Trainees to Attempt Cannulation on Success Rate of Selective Cannulation During hands-on ERCP Training
Status: COMPLETED
Conditions: Disease as Reason for ERCP
Interventions: PROCEDURE: Hands-on ERCP training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tracheal Intubation vs. Bag-valve-mask Ventilation in Patients With Out-of-Hospital Cardiac Arrest _ CAAM STUDY
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: PROCEDURE: bag-valve-mask ventilation|PROCEDURE: tracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence Of Salmeterol Xinafoate/Fluticasone Propionate (50/500 µg BID) On The Course Of The Disease And Exacerbation Frequency In COPD Patients Gold Stage III And IV
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Salmeterol / Fluticasone (50/500 µg) BID fixed combination|DRUG: Salmeterol / Fluticasone (50/500 µg) BID separate Inhalers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma (MCL)
Interventions: DRUG: ACP-196 (acalabrutinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Laser TURP With and Without Dutasteride.
Status: TERMINATED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Dutasteride (Avodart)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Status: NO_LONGER_AVAILABLE
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Secondary Myelofibrosis
Interventions: DRUG: Busulfan|DRUG: Cytarabine|DRUG: Fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: EXPANDED_ACCESS
Clinical trial: The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty
Status: RECRUITING
Conditions: Arthritis Knee|Knee Osteoarthritis|Pain, Postoperative
Interventions: DRUG: Methylprednisolone 4 milligram Tab|DRUG: Dexamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MBI and Breast Tomosynthesis Screening Accuracies in Patients With Dense Breast Tissue
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DEVICE: MBI Scan: The LumaGEM®|DEVICE: 3D Mammogram/Breast Tomosynthesis Scan: Selenia® Dimensions®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems
Status: COMPLETED
Conditions: Anxiety Disorders|Social Anxiety Disorder|Generalized Anxiety Disorder|Panic Disorder|Persistent Depressive Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Transdiagnostic Internet-delivered REBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Status: COMPLETED
Conditions: Glioma|Low-grade Glioma|Astrocytoma
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Immunogenicity and Safety of MVC-COV1901 Compared With AZD1222 Against COVID-19 in Adults
Status: COMPLETED
Conditions: Covid19 Vaccine
Interventions: BIOLOGICAL: MVC-COV1901|BIOLOGICAL: AZD1222
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase III Study of Palliative Radiation of Advanced Central Tumors With Intentional Avoidance of the Esophagus
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: RADIATION: Conventional radiotherapy|RADIATION: Esophageal-Sparing Intensity-Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)
Status: RECRUITING
Conditions: Radiotracer|Hypertension|Cholesterol
Interventions: DRUG: Dexamethasone (Group 2)|DRUG: Cosyntropin (Group 3)|COMBINATION_PRODUCT: PET/CT Scan with FNP-59
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pilot Study on the Effect and Safety of Iluvien® in Chronic Diabetic Macular Edema Patients
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: IlUVIEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating mCRPC Treatment Using PSMA [Lu-177]-PNT2002 Therapy After Second-line Hormonal Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: [Lu-177]-PNT2002|DRUG: Abiraterone|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Losartan in Preventing Progression of COPD
Status: COMPLETED
Conditions: COPD|Emphysema|Chronic Bronchitis|Smoking
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Non-hormonal Vaginal Preparations in Treating Vaginal Dryness
Status: COMPLETED
Conditions: Vaginal Dryness
Interventions: DEVICE: Vagisan® Moisturising Cream|DEVICE: Gynomunal® vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soluble Fibre Enriched CHO Food Study
Status: UNKNOWN
Conditions: Diabetes|Healthy
Interventions: DIETARY_SUPPLEMENT: Bread|DIETARY_SUPPLEMENT: Mashed Potatoes|DIETARY_SUPPLEMENT: Muffins|DIETARY_SUPPLEMENT: Hot Breakfast Cereal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: R-ACVBP and DA-EPOCH-R in Patients With Non-GCB DLBCL
Status: UNKNOWN
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Rituximab|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Prednisone|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Vindesine|DRUG: Bleomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of Minimally Invasive Surgery Versus Standard Surgery for Correction of Hallux Valgus
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: PROCEDURE: conventional surgical technique - Chevron-type distal metatarsal osteotomy|PROCEDURE: minimally invasive surgical technique|PROCEDURE: minimally invasive surgical technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DRUG: Duloxetine 30 MG|DRUG: Nonsteroidal Antiinflammatory Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Oral Cavity|Squamous Cell Carcinoma of the Oropharynx
Interventions: DRUG: GC4419
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Impact of Multidisciplinary Oncosexology Management Associated With Photobiomodulation on Sexual Quality of Life in Women With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Switching to Flumatinib Versus Dasatinib After Imatinib-related Low-grade Adverse Events in CML-CP Patients
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia in Chronic Phase
Interventions: DRUG: Flumatinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab-containing Induction Effects on Stem Cells Mobilization, colLection and Engraftment in Newly Diagnosed Multiple MyelomA Patients.
Status: RECRUITING
Conditions: Multiple Myeloma|Daratumumab|Autologous Stem Cell Transplantation|Leukapheresis
Interventions: DRUG: Daratumumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function
Status: COMPLETED
Conditions: Cognitive Impairment|Estrogen Deficiency|Menopause|Endothelial Dysfunction|Vascular Stiffness
Interventions: OTHER: GnRHant + E2|OTHER: GnRHant + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Study to Evaluate Hematopoietic Progenitor Cell Mobilization in Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Bone Marrow Transplant Complications
Interventions: PROCEDURE: Autologous hematopoietic cell transplant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of Removing Blood Stasis Therapy in Treating Acute Cerebral Hemorrhage Safety and Efficacy
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage, Hypertensive|Traditional Chinese Medicine
Interventions: DRUG: AICH-PXZY|DRUG: AICH-without PXZY|DRUG: AICH-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Thrombocytopaenia
Interventions: DRUG: SB497115|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Cholangiocarcinoma|Gastric Cancer|Esophageal Cancer|Colorectal Cancer
Interventions: DRUG: ZSP1241
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Understand the Safety and Effects of a C. Difficile Vaccine With New Adds-Ons That Will Be Given to Healthy Adults
Status: RECRUITING
Conditions: Clostridoides Difficile Associated Disease
Interventions: BIOLOGICAL: C. difficile vaccine (previously studied formulation).|BIOLOGICAL: C. difficile vaccine formulation 1.|BIOLOGICAL: C. difficile vaccine formulation 2.|BIOLOGICAL: C. difficile vaccine formulation 3.|OTHER: Saline Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor Versus Clopidogrel for CMD in Patients With AMI: A Retrospective Study Based on the Angio-IMR
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Dual antiplatelet therapy with aspirin and either ticagrelor or clopidogrel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip Patient
Status: UNKNOWN
Conditions: Unilateral Complete Cleft Lip
Interventions: DEVICE: Grayson's presurgical nasoalveolar molding|DEVICE: Figueroa's presurgical nasoalveolar molding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research of SORD-CMT Natural History and Epalrestat Treatment
Status: NOT_YET_RECRUITING
Conditions: Charcot-Marie-Tooth Disease (CMT)
Interventions: DRUG: Epalrestat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tekturna on Endothelial Function and Endothelial Progenitor Cells in Patients With Early Atherosclerosis
Status: TERMINATED
Conditions: Endothelial Dysfunction
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration
Status: NOT_YET_RECRUITING
Conditions: Bone Loss|Bone Lesion
Interventions: PROCEDURE: hyaluronic acid added to hydroxyapetite|PROCEDURE: Hydroxyapatite alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lubiprostone in Combination With Standard PEG Preparation
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Lubiprostone|OTHER: Polyethylene glycol with electrolytes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Regional Citrate Anticoagulation for RRT During V-V ECMO
Status: RECRUITING
Conditions: ARDS, Human|Acute Kidney Injury
Interventions: DRUG: Unfractionated heparin + RCA first|DRUG: Unfractionated heparin first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceramide Containing Multivesicular Emulsion Application . . .
Status: COMPLETED
Conditions: Foot Transepidermal Water Loss in Patients in NIDDM|Foot Dryness in Patients With NIDDM
Interventions: DRUG: CeraVe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Diffuse Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Diffuse Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: single dose of CNCT19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial
Status: RECRUITING
Conditions: Post-operative Pain|Post-operative Delirium|Post-cardiac Surgery|Chronic Pain|Opioid Use Disorder|Anesthesia, Local
Interventions: PROCEDURE: Intermittent Superficial Parasternal Intercostal Plane Block - Experimental|PROCEDURE: Intermittent Superficial Parasternal Intercostal Plane Block - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study
Status: RECRUITING
Conditions: Pre-exposure Prophylaxis|HIV Prevention|Pregnancy Related
Interventions: DRUG: Initiating daily oral PrEP during pregnancy|DRUG: Already using daily oral PrEP at the time of pregnancy diagnosis|DRUG: Initiating injectable PrEP during pregnancy|DRUG: Already using injectable PrEP (CAB-LA) at the time of pregnancy diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Arginine Butyrate and Ganciclovir/Valganciclovir in EBV(+) Lymphoid Malignancies
Status: TERMINATED
Conditions: EBV Lymphomas|Lympho-proliferative Diseases
Interventions: DRUG: Arginine Butyrate|DRUG: Ganciclovir|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Early Stages NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: Cisplatin|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grazoprevir and Elbasvir Without Ribavirin for 12 Weeks in Patients With HCV-related Cryoglobulinemic Nephropathy
Status: UNKNOWN
Conditions: Hepatitis C|Cryoglobulinaemic Glomerulonephritis
Interventions: DRUG: Elbasvir/Grazoprevir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Health and Wellness Policies of the New Haven Public School District.
Status: COMPLETED
Conditions: Chronic Diseases|Obesity
Interventions: OTHER: DISTRICT WELLNESS COMMITTEE|OTHER: NUTRITIONAL QUALITY OF FOODS AND BEVERAGES ON CAMPUS|OTHER: HEALTH PROMOTION AND MARKETING|OTHER: OPPORTUNITIES FOR PHYSICAL ACTIVITY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sugammadex vs Placebo to Prevent Residual Neuromuscular Block
Status: COMPLETED
Conditions: General Surgery
Interventions: DRUG: Sugammadex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa
Status: COMPLETED
Conditions: Moderate Depression|Clinical Depression|Postpartum Depression
Interventions: BEHAVIORAL: basic counselling by lay-health workers|OTHER: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of COTI-2 as Monotherapy or Combination Therapy for the Treatment of Malignancies
Status: UNKNOWN
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Endometrial Cancer|Cervical Cancer|Peritoneal Cancer|Head and Neck Cancer|HNSCC|Colorectal Cancer|Lung Cancer|Pancreatic Cancer
Interventions: DRUG: COTI2|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IOP-Lowering Efficacy of Brinzolamide 1.0% Added to Travoprost 0.004%/Timolol 0.5% Fixed Combination as Adjunctive Therapy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Azopt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Operations on the Thyroid Gland and Hyoid Suspension in Patients With Combined Thyroid Pathology and OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|Obstructive Sleep Apnea-hypopnea|Obstructive Sleep Apnea-hypopnea Syndrome
Interventions: PROCEDURE: Simultaneous thyroidectomy and hyoid suspension|PROCEDURE: Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimum Effective Concentration of Ropivacaine for Brachial Plexus Block Via the Supraclavicular and Infraclavicular Approach, Femoral Nerve Block, Sciatic Nerve Block Via the Popliteal and Parasacral Approach
Status: TERMINATED
Conditions: Surgical Anesthesia
Interventions: DRUG: Ropivacaine concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effects of Snuff and/or Red Wine om Metabolic Rate
Status: UNKNOWN
Conditions: Metabolic Rate|Hunger|Insulin Sensitivity
Interventions: OTHER: Wine with or without alcohol and snuff with or without nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standard Reaming Versus Reaming/Irrigating/Aspirating for Intramedullary Nailing of Femoral Shaft Fractures
Status: COMPLETED
Conditions: Femoral Fractures
Interventions: PROCEDURE: Standard Reaming|PROCEDURE: Reaming/Irrigating/Aspirating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multi-centre Study Comparing the Effects of AZD2927 and Placebo on the Electrical Activity in the Heart in Patients
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: AZD2927|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Light Emitting Diode for theTreatment of Genitourinary Syndrome of Menopause Associated With Breast Cancer Treatment
Status: COMPLETED
Conditions: Atrophy;Vaginal|Breast Cancer
Interventions: PROCEDURE: Experimental: LED group|PROCEDURE: Sham Comparator: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Protective Behavioral Strategies and Brief Alcohol Interventions
Status: COMPLETED
Conditions: Alcohol Consumption
Interventions: BEHAVIORAL: Protective Behavioral Strategies|BEHAVIORAL: Personalized Normative Feedback|BEHAVIORAL: Alcohol Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prevalence of Geophagy and Knowledge About Its Health Effects Among Native Sub-Saharan Africa, Caribbean and South America Healthy Adults Living in France
Status: COMPLETED
Conditions: Geophagia
Interventions: OTHER: Questionnaire about geophagia (knowledge about soil/clay consumption and knowledge of the health effects of geophagy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omalizumab With Oral Food Immunotherapy With Food Allergies Open Label Safety Study in a Single Center
Status: COMPLETED
Conditions: Immune System Diseases
Interventions: DIETARY_SUPPLEMENT: Food proteins|DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With an Open-Label Active Control to Evaluate the Potential of Nestorone® to Delay Cardiac Repolarization in Healthy Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Supratherapuetic dose of Nestorone|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Safety and Anti-HIV Effect of GSK1265744 Versus Placebo in HIV-1 Infected Adults (ITZ112929)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK1265744 30mg|DRUG: Placebo|DRUG: GSK1265744 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Simvastatin on Uterine Leiomyoma Size
Status: RECRUITING
Conditions: Fibroid Uterus|Fibroid Tumor|Leiomyoma|Fibromyoma|Leiomyoma, Uterine
Interventions: DRUG: Simvastatin 40mg|DRUG: Placebo 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SYMPTOM MANAGEMENT EDUCATION GIVEN WITH MICRO TEACHING METHOD ENRICHED WITH STANDARD PATIENT IN PALLIATIVE CARE
Status: RECRUITING
Conditions: Palliative Care
Interventions: OTHER: Micro-teaching enriched with standard patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BALANCE Diet Implementation in Primary Health Care: a Cluster Randomized Type II Hybrid Implementation Study
Status: COMPLETED
Conditions: Obesity|Hypertension|Diabetes|Dyslipidemias
Interventions: OTHER: Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of OM-85 BV on Wheezing Related Morbidity in Children With Recurrent Wheezing
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: OM-85 BV (Broncho-Vaxom)|DRUG: OM-85 BV (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Brachio Basilic Arterio Venous Fistula One Stage vs Two Stage
Status: NOT_YET_RECRUITING
Conditions: Arterio-venous Fistula
Interventions: PROCEDURE: Brachio basilic arterio venous fistula one stage versus two stage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Due to Burn Injury
Status: COMPLETED
Conditions: Pain|Burn Injury
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-regulation Strategies to Improve Exercise Behavior Among Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia|Schizo-affective Disorder
Interventions: BEHAVIORAL: Implementation Intentions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DIAGNOSTIC_TEST: Whole body 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study on the Prevention of Mild to Moderate Intermittent Asthma With Chinese Medicine Weiyang Yuping Fang
Status: ENROLLING_BY_INVITATION
Conditions: Bronchial Asthma
Interventions: DRUG: Weiyang Yuping Fang
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mass Closure vs Layer by Layer Closure
Status: RECRUITING
Conditions: Abdominal Wall Wound|Ventral Hernia|Incisional Hernia
Interventions: OTHER: Mass closure vs layer by layer closure of transverse laparotomy incisions in children and infants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Mouthwash in Reducing the Symptoms Associated With Flu and Cold Viruses
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AMG 319 Lymphoid Malignancy FIH
Status: COMPLETED
Conditions: Cancer|Chronic Lymphocytic Leukemia|Diffuse Large Cell Lymphoma|Hematologic Malignancies|Hematology|Leukemia|Low Grade Lymphoma|Lymphoma|Mantle Cell Lymphoma|Non-Hodgkin's Lymphoma|Oncology|Oncology Patients|T Cell Lymphoma|Tumors
Interventions: DRUG: AMG 319
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resiliency Through Azithromycin for Children (REACH), Côte d'Ivoire
Status: COMPLETED
Conditions: Child Mortality|Azithromycin
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pilot Study - Patient Education and Pelvic Strength Exercises in Elderly Women With Incontinence.
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Transcutaneous Electrical Nerve Stimulation (TENS) for Chronic Pain of Predominantly Peripheral Neuropathic Origin
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DEVICE: Transcutaneous Nerve Stimulation (TENS)|DEVICE: Cefar Primo Pro TENS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aromatherapy on Childbirth
Status: UNKNOWN
Conditions: Parturition|Natural Childbirth|Labor Pain
Interventions: OTHER: Aromatherapy oil|OTHER: None essential oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Omega-3 Fatty Acids in Bipolar Patients With a Low Omega-3 Index and Reduced Heart Rate Variability
Status: COMPLETED
Conditions: Bipolar Disorders
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acids (EPAX 6015 TG)|DIETARY_SUPPLEMENT: Corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the " Tele-follow-up " for the Follow-up of Implantable Defibrillators
Status: COMPLETED
Conditions: Defibrillators, Implantable|Telemedicine
Interventions: OTHER: Tele- follow-up|OTHER: Conventional follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of an Anti-CD20 Monoclonal Antibody (AME-133v) to Treat Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: AME-133v (LY2469298)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Effect of Vagal Nerve Stimulation at Rest and Pain
Status: WITHDRAWN
Conditions: Healthy Volunteer
Interventions: DEVICE: active transcutaneous Vagal Nerve Stimulation (tVNS)|DEVICE: sham transcutaneous Vagal Nerve Stimulation (tVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevailing Microorganisms Causing Neonatal Sepsis in Neonatal Intensive Care Unit (Prospective Study)Prevailing Microorganisms Causing Neonatal Sepsis in Neonatal Intensive Care Unit (Prospective Study)
Status: UNKNOWN
Conditions: Neonatal SEPSIS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: a Randomized, Placebo-controlled, Double-blind Clinical Study
Status: COMPLETED
Conditions: Male Infertility
Interventions: DRUG: Korean Red Ginseng (KRG)|PROCEDURE: Varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 12-Week Safety and Efficacy Study of BCX4161 as an Oral Prophylaxis Against HAE Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema|HAE
Interventions: DRUG: BCX4161|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Strategies to Reduce the Impact of the Relative Age Effect in Kindergarten
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Relative Age Effect Intervention|OTHER: School as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BC3402 in Combination With Durvalumab in Patients With Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: BC3402 injection|DRUG: Durvalumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Status: COMPLETED
Conditions: Scar Keloid
Interventions: DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome
Status: UNKNOWN
Conditions: COVID|Acute Respiratory Distress Syndrome
Interventions: DRUG: Angiotensin II|DRUG: Interleukin-1 receptor antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Importance of Dosing Regimen for the Effect of Vitamin D Supplementation
Status: COMPLETED
Conditions: Hypovitaminosis D
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Controled Study on the Outcome of Greenhouse Tec in the Arthroscopic Treatment of Small to Medium Rotator Cuff Tear
Status: COMPLETED
Conditions: Bone Marrow Stimulating|Modified Suture Bridge
Interventions: PROCEDURE: The combination of bone marrow stimulation and modified suture bridge(Greenhouse tec)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cellular Adoptive Immunotherapy in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic autologous lymphocytes|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mesalamine and Amitriptyline on Irritable Bowel Syndrome
Status: WITHDRAWN
Conditions: Diarrhea- Predominant Irritable Bowel Syndrome|Quality of Life
Interventions: DRUG: Mesalazine(asacol 800 mg)|DRUG: Amitriptyline|DRUG: placebo like asacol|DRUG: placebo like amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanuts Second Meal Glycemic Response
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Whole peanuts without skins, Peanut butter, or no peanuts (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Intraoperative and Postoperative Effects of Warming Patients in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: warmed with electric blankets|OTHER: patients without warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) - Based Planning and Creation of Orthodontic Appliances
Status: UNKNOWN
Conditions: Orthodontics
Interventions: PROCEDURE: orthodontic treatment with customized archwires|PROCEDURE: orthodontic treatment with prefabricated archwires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Sentinel Lymph Node Identification in Colon Carcinoma Using Intravenous Bevacizumab-800CW
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colon Neoplasm|Sentinel Lymph Node|Fluorescence
Interventions: PROCEDURE: Sentinel lymph node detection using intravenous bevacizumab-800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy of Internet-delivered CBT for Insomnia in a National Cohort of Danish Breast Cancer Survivors
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: iCBT for Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of an Aerobic and Resistance Exercise Program With Cognitive Training Post-stroke
Status: COMPLETED
Conditions: Cerebral Stroke
Interventions: BEHAVIORAL: CARET|BEHAVIORAL: CTI|BEHAVIORAL: Sham CARET|BEHAVIORAL: Sham CTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Study of Donepezil in Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: donepezil|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Hypofractionated Intensity-modulated Radiation Therapy in Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervix Cancer|Radiotherapy, Adjuvant|Radiotherapy, Intensity-Modulated|Hypofractionated Dose
Interventions: RADIATION: POHIM-RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic Alone
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Bupivacaine, Clonidine, Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia
Interventions: DRUG: N-Acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety for Different Regimen of VTE Pharmacoprophylaxis Among Severely Burn Patients
Status: COMPLETED
Conditions: Burns
Interventions: DRUG: Enoxaparin 40 mg q24 hours|DRUG: Enoxaparin 30 mg q12 hours|DRUG: Unfractionated heparin 5000 U q8 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Analgesic Activity of ATx08-001 in Subjects With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: ATx08-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes
Status: UNKNOWN
Conditions: Gestational Diabetes
Interventions: DEVICE: Dexcom G System|DEVICE: Self monitoring blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASCEND: A Study of Cardiovascular Events iN Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus
Interventions: DRUG: Aspirin|DRUG: Omega-3 Ethyl Esters|DRUG: Placebo Aspirin|DRUG: Placebo Omega-3 Ethyl Esters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psychosis|Intellectual Disability
Interventions: DRUG: Clozapine|DRUG: haloperidol, pimozide, olanzapine, risperidone, amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery
Status: COMPLETED
Conditions: Elderly Patients|Solid Organ Cancer|Surgical Resection|Epidural Anesthesia|Long-term Outcome
Interventions: PROCEDURE: Combined epidural-general anesthesia|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Insertion Distance of Interscalene Perineural Catheters in the Context of Shoulder Surgery.
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Insertion of interscalene catheter for shoulder surgery|PROCEDURE: Insertion of interscalene catheter for shoulder surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Inflammatory Indexes and CHA2DS2-VASc Score for LVT in ANT-MI With Left Ventricular Dysfunction
Status: COMPLETED
Conditions: Left Ventricular Thrombus|Acute Anterior Myocardial Infarction|Left Ventricular Dysfunction
Interventions: OTHER: inflammatory indexes and CHA2DS2-VASc score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of a Long-Acting Injectable Steroid to Treat Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: EP-104IAR|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Gemcitabine Combined With Either Cetuximab or Erlotinib in Treating Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: gemcitabine hydrochloride|BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of NVA237 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Tiotropium|DRUG: Placebo to tiotropium|DRUG: Placebo to NVA237|DRUG: salbutamol/albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Intraoperative Patient Warming Systems
Status: UNKNOWN
Conditions: Orthopedic Surgery|General Anesthesia
Interventions: DEVICE: vitalHEAT vH2 Temperature Management System|DEVICE: Arizant Healthcare Bair Hugger Temperature Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients
Status: WITHDRAWN
Conditions: Chronic Pain|Chronic Insomnia|Opioid Use
Interventions: BEHAVIORAL: NiteCAPP HELPS|OTHER: Tapered Withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT