pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women
Status: RECRUITING
Conditions: Dyslipidemias|Hypertriglyceridemia|Hypercholesterolemia|Hyper-LDL-cholesterolemia|Hypo HDL Cholesterolaemia|Postmenopausal Symptoms
Interventions: DRUG: Phytoestrogen|DRUG: Diet control & life style modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AN2728 Topical Ointment, 2% in Children, Adolescents, and Adults (Ages 2 Years and Older) With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: AN2728 Topical Ointment, 2%|DRUG: Matching vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Emptying of Maltodextrin Solution in Elderly and in Adults
Status: UNKNOWN
Conditions: Aspiration; Liquids|Fasting|Perioperative Pulmonary Aspiration
Interventions: DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Elderly Primary Insomnia Polysomnographic Study (0928-002)(TERMINATED)
Status: TERMINATED
Conditions: Primary Insomnia
Interventions: DRUG: MK0928, gaboxadol / Duration of Treatment - 6 weeks|DRUG: Comparator: placebo / Duration of Treatment - 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial
Status: COMPLETED
Conditions: Thalassemia|Hepatitis C
Interventions: DRUG: sofosbuvir/velpatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus as Therapeutic Approach to Uveitis
Status: COMPLETED
Conditions: Uveitis|Intermediate Uveitis|Posterior Uveitis|Panuveitis
Interventions: DRUG: Sirolimus (rapamycin)|DRUG: Sirolimus (rapamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D on Skeletal Muscle Strength in Resistance Trained Adult Females
Status: UNKNOWN
Conditions: Nutrition Status|Nutritional Requirements|Sports Nutritional Sciences
Interventions: DIETARY_SUPPLEMENT: Nature Made Vitamin D3 5,000 IU, 125mcg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association Between Laser Interferometric Measurement of Fundus Pulsation and Pneumotonometric Measurement of Pulsatile Ocular Blood Flow in Patients With Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: PROCEDURE: blood flow measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of Tofacitinib (TF) With Iguratimod (IGU) on RA
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Iguratimod|DRUG: Tofacitinib|DRUG: Pred
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Blazer Open-Irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation (PAF)
Interventions: DEVICE: Blazer Open-Irrigated Ablation Catheter (Boston Scientific)|DEVICE: FDA Approved Open-Irrigated Ablation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Epithelial Dysplasia Informational Needs Questionnaire
Status: COMPLETED
Conditions: Oral Epithelial Dysplasia|Precancerous Conditions|Precancerous Lesions|Oral Lichen Planus|Oral Leukoplakia|Oral Leukoplakia of Tongue|Oral Leukoplakia of Lips|Oral Leukoplakia of Gingiva|Oral Erythroplakia|Chronic Hyperplastic Candidosis|Oral Submucous Fibrosis|Oral Submucosal Fibrosis, Including of Tongue|Oral Disease|Dental Diseases|Dysplasia|Information Seeking Behavior|Patient Preference|Information Needs|Health Behavior|Quality of Life|Preference, Patient|Patient Satisfaction|Patient Engagement|Patient Participation
Interventions: OTHER: No intervention is planned for this study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diet and Hip Fracture Risk in the United Kingdom Women's Cohort
Status: COMPLETED
Conditions: Hip Fracture (First Incidence of)
Interventions: OTHER: Dietary pattern|OTHER: Fruit and vegetable intake|OTHER: Meat intake|OTHER: Fish intake|OTHER: Egg intake|OTHER: Dairy intake|OTHER: Tea intake|OTHER: Coffee intake|OTHER: Tea and coffee intake|OTHER: Protein intake|OTHER: Calcium intake|OTHER: Vitamin D intake
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multimodal Analysis and Electroretinogram in VKH From Acute Onset - Part I
Status: COMPLETED
Conditions: Uveomeningoencephalitic Syndrome|Inflammation|Choroid Disease|Visual Impairment
Interventions: DRUG: Meticorten
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomised Trial of Chemotherapy Plus Surgery for Recurrent Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Gemcitabine/Carboplatin|DRUG: Gemcitabine/Cisplatin|DRUG: Docetaxel/Oxaliplatin|DRUG: Docetaxel/Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Anti-Hepatitis C Virus (Anti-HCV) Trial of Peg-Interferon and Ribavirin in Subjects of First Nations, Metis and Caucasian Ethnicity
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pegylated Interferons (Peg-IFN) and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: All-trans Retinoic Acid, and Arsenic +/- Idarubicin
Status: COMPLETED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: All-Trans Retinoic Acid (ATRA)|DRUG: Arsenic Trioxide (ATO)|DRUG: Idarubicin|DRUG: Gemtuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for Bleeding in Breast Surgery
Status: UNKNOWN
Conditions: Hematoma|Seroma
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Single Intravitreal Injection HB002.1M in Subjects With Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: HB002.1M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS
Status: WITHDRAWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Placebo|DRUG: Arimoclomol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension
Status: RECRUITING
Conditions: Heart Failure Patients With Pulmonary Hypertension
Interventions: DEVICE: Gradient Denervation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
Status: COMPLETED
Conditions: Carotid Atherosclerosis|Stroke|Type 2 Diabetes|Metabolic Syndrome
Interventions: DRUG: atorvastatin|DRUG: rimonabant|DRUG: rosiglitazone|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of the Ozone Application in Two-Visit Indirect Pulp Therapy of Permanent Molars With Deep Carious Lesion
Status: COMPLETED
Conditions: Ozone|Caries
Interventions: OTHER: Ozone|OTHER: chlorhexidine digluconate|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Bloodletting Acupuncture for Subacute and Chronic Non-specific Low Back Pain
Status: RECRUITING
Conditions: Back Pain, Low
Interventions: PROCEDURE: Bloodletting acupuncture at the fossa poplitea|PROCEDURE: Bloodletting acupuncture at the regio glutaea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hemi- Versus Total Shoulder Arthroplasty Using Implants of the "Epoca" System
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Hemiarthroplasty|PROCEDURE: Total arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Dimension Tomography of Eye Structures by White Light Imaging Device
Status: UNKNOWN
Conditions: Healthy Subjects|Moderate to Severe Keratoconjunctivitis Sicca (KCS)|Dry Eye Syndrome (DES)
Interventions: DEVICE: None invasive imaging of the tear film (AdOM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Long-term Hepatitis A and B Antibody Persistence in Healthy Adult Subjects, Primed 16 to 20 Years Earlier With GSK Biologicals' Combined Hepatitis A and B Vaccine, Twinrix® (SB208127) in Study HAB-084 (208127/084)
Status: WITHDRAWN
Conditions: Hepatitis B|Hepatitis A
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Bemarituzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Supervised Progressive Resistance Training With Breast Cancer Patients During Adjuvant Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer|Cancer-related Fatigue
Interventions: OTHER: Supervised progressive resistance training|OTHER: Supervised progressive muscle relaxation training (Jacobson method)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Plus Entecavir vs. Tenofovir in Adefovir-Resistant Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Viral Hepatitis B Without Delta-agent
Interventions: DRUG: Tenofovir|DRUG: Entecavir|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Pharmacokinetics and Pharmacodynamics of Insulin Aspart to NovoRapid® Penfill® in Healthy Subjects
Status: COMPLETED
Conditions: Clamp Study
Interventions: DRUG: Insulin Aspart|DRUG: NovoRapid® Penfill®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Functional Strength Training and Neuromuscular Electrical Stimulation in Severe Acute Exacerbations of COPD
Status: RECRUITING
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease|Acute Exacerbation of COPD
Interventions: OTHER: Functional strength training|DEVICE: NMES|DRUG: Daily medical treatment (e.g., oxygen, medrol, duovent, azitromycine)|OTHER: Routine physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DRUG: 2-hydroxybenzylamine acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quadrant Versus Superficial Parotidectomy
Status: WITHDRAWN
Conditions: Pleomorphic Adenoma of the Parotid Gland
Interventions: PROCEDURE: Quadrant parotidectomy|PROCEDURE: Superficial parotidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents
Status: RECRUITING
Conditions: Rumination
Interventions: BEHAVIORAL: Mindfulness (Headspace) App|BEHAVIORAL: Active Control Condition ("Recharge" condition delivered in Headspace app)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Antibiotics After Breast Reduction:Clinical Trial With Randomization
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Cephalexin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Study of ManNAc for GNE Myopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: GNE Myopathy
Interventions: DRUG: ManNAc|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Acute Intermittent Hypoxia on Motor Learning
Status: ENROLLING_BY_INVITATION
Conditions: Incomplete Spinal Cord Injury
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: SHAM Acute Intermittent Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ir-CPI in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ir-CPI - Dose 1|DRUG: Ir-CPI - Dose 2|DRUG: Ir-CPI - Dose 3|DRUG: Ir-CPI - Dose 4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Brequinar in Subjects With Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Brequinar/Brequinar + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
Status: COMPLETED
Conditions: Ovulation Induction|Infertility
Interventions: DRUG: Choriogonadotropin alpha (r-hCG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fullscale_Intervention Study: Genetic Risk Communication in Coronary Heart Disease and Wearables
Status: NOT_YET_RECRUITING
Conditions: Fitness Trackers|Sedentary Time|Genetic Predisposition to Disease|Coronary Heart Disease
Interventions: GENETIC: Genetic Risk Estimate+Health Coaching|DEVICE: Genetic Risk Estimate + Fitbit Functions+Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Disease|Aging|Amyloidosis|Aortic Valve Stenosis
Interventions: OTHER: a basal LV septum biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: BI 2536 Infusional Treatment in Patients Over 60 Years of Age With Refractory or Relapsed Acute Myeloid Leukaemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: BI 2536
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Ipilimumab|PROCEDURE: Cryoablation|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Yoga for Social Isolation and Loneliness in Rural Veterans
Status: ACTIVE_NOT_RECRUITING
Conditions: Loneliness|Social Isolation
Interventions: BEHAVIORAL: Virtual Yoga at First 8 weeks|BEHAVIORAL: Virtual Yoga at Second 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Study Between Single Versus Dual Trigger for Poor Responders in GnRH-antagonist ICSI Cycles
Status: COMPLETED
Conditions: Assisted Reproduction
Interventions: DRUG: combined oral contaraceptive pills|DRUG: recombinant FSH|DRUG: Urinaru gonadotropin|DRUG: GnRH antagonist|DRUG: Human chorionic gonadotropin|DRUG: GnRH agonist|PROCEDURE: Ovum pick up|PROCEDURE: Embryo transfer|DRUG: natural Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uncemented Versus Cemented Total Hip Arthroplasty for Displaced Intracapsular Hip Fractures
Status: TERMINATED
Conditions: Hip Fractures
Interventions: DEVICE: Total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pixantrone, Cytarabine, Methylprednisolone, and Cisplatin in Treating Patients With Aggressive Non-Hodgkin's Lymphoma in First Relapse
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cisplatin|DRUG: cytarabine|DRUG: methylprednisolone|DRUG: pixantrone dimaleate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: OTHER: Educational Intervention|OTHER: Meditation Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Probiotics on E. Coli-induced Gastroenteritis
Status: COMPLETED
Conditions: Gastroenteritis|Bacterial Infection|Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now
Status: RECRUITING
Conditions: Communication
Interventions: BEHAVIORAL: PFC I-PASS Intervention|BEHAVIORAL: PFC I-PASS+ Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1, 2-Part, Single Ascending Dose Assessment of the Safety, Tolerability, and Pharmacokinetics of Rolapitant Intravenous in Healthy Volunteers
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Rolapitant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Status: RECRUITING
Conditions: Focal Epilepsy
Interventions: DRUG: BHV-7000|DRUG: BHV-7000|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)
Status: NOT_YET_RECRUITING
Conditions: Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: ABP 234|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Compare the Safety and Effect of Efgartigimod as an Intravenous Infusion With the Effect of Efgartigimod as a Subcutaneous Injection in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: efgartigimod IV|BIOLOGICAL: efgartigimod PH20 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of TGR 1202 in Patients With Relapsed or Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia|Peripheral T-Cell Lymphoma|Hodgkin's Lymphoma
Interventions: DRUG: TGR-1202
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty
Status: COMPLETED
Conditions: Knee Joint Osteoarthrosis|Hyperalgesia|Severe Movement Related Pain
Interventions: DRUG: Methylprednisoloneacetate|DRUG: Lidocaine|OTHER: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease
Status: RECRUITING
Conditions: Liver Cirrhosis|Hepato-Renal Syndrome|Chronic Kidney Diseases
Interventions: DRUG: terlipressin or noradrenalin plus albumin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Efficacy and Safety of Secukinumab in Participants With Active Psoriatic Arthritis With Axial Skeleton Involvement
Status: COMPLETED
Conditions: Axial Psoratic Arthritis
Interventions: BIOLOGICAL: Secukinumab|DRUG: Secukinumab and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
Status: UNKNOWN
Conditions: aGVHD|cGVHD
Interventions: DRUG: Rabbit ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Remediation VR Tool for People With MCI: a Feasibility RCT
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Remediation|Virtual Reality|Psychiatric Rehabilitation
Interventions: DEVICE: Virtual Reality Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Circadian Clock System on Perioperative Cognitive Function of Elderly Patients
Status: UNKNOWN
Conditions: Circadian Clock|Postoperative Cognitive Function|General Anesthesia|Elderly Patients
Interventions: OTHER: receiving operation during the day or at night
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy
Status: COMPLETED
Conditions: Chronic Gout
Interventions: DRUG: SEL-212 low-dose|DRUG: SEL-212 high-dose|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma|Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Adenocarcinoma
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|OTHER: Radiological Assessments|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Changes in Response to Long-Duration Isolation and Confinement
Status: ACTIVE_NOT_RECRUITING
Conditions: Isolation, Social|Virtual Reality|Spatial Navigation
Interventions: BEHAVIORAL: Isolation and Confinement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Methylene Blue MMX®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Comparison of the Effect of Carvedilol and Metoprolol on Airways Tone in Patients With Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure|Chronic Obstructive Airway Disease
Interventions: DRUG: Carvedilol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction
Status: COMPLETED
Conditions: Non Invasive Ventilation|Patient Ventilator Interaction
Interventions: DEVICE: Neurally Adjusted Ventilatory Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Trial of Ultrasound Versus Landmark Guided Central Venous Access in the Pediatric Population
Status: COMPLETED
Conditions: Need for Central Venous Access
Interventions: PROCEDURE: central line placement|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Treatment for Psychosis and/or Obsessive Compulsive Disorder With Probable Immune System Involvement
Status: ENROLLING_BY_INVITATION
Conditions: Obsessive-Compulsive Disorder|Obsessive-Compulsive Behavior|Schizophrenia|Delusional Disorder|Brief Psychotic Disorder|Schizo Affective Disorder|Other Psychoses|Unspecified Psychosis
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Physiological Markers of Emotional Trauma: A Randomized Controlled Comparison of Mind-Body Therapies
Status: COMPLETED
Conditions: Hypermobility, Joint|Depression|Anxiety
Interventions: BEHAVIORAL: Emotional Freedom Techniques (EFT)|BEHAVIORAL: Diaphragmatic Breathing (DB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK1362885 in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK1362885|DRUG: GSK1362885
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Dacryointubation vs Bicanalicular Intubation for Proximal Tear Duct Obstruction
Status: COMPLETED
Conditions: Lacrimal Duct Obstruction|Lacrimal Apparatus Diseases|Lacrimal Stenosis|Lacrimal Elimination
Interventions: DEVICE: Bicanalicular intubation|PROCEDURE: Closed dacryointubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angioplasty and Heart Stents to Treat Individuals With an Occluded Artery Following a Heart Attack
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction
Interventions: DEVICE: PCI with stenting|BEHAVIORAL: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
Status: RECRUITING
Conditions: Dry Eye
Interventions: DRUG: VSJ-110|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Weight and Shape Concern Among Women With High Body Weight
Status: RECRUITING
Conditions: Body Image Disturbance|Overweight and Obesity|Weight Loss
Interventions: BEHAVIORAL: Modified Body Project|BEHAVIORAL: Facts about obesity, myths about weight loss|BEHAVIORAL: Lifestyle intervention for weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine for Post-operative Pain in Mohs
Status: COMPLETED
Conditions: Pain, Postoperative|Narcotic Use
Interventions: DRUG: Bupivacaine|OTHER: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nasal and Systemic Immune Responses to Nasal Influenza Vaccine
Status: COMPLETED
Conditions: Influenza|Vaccine Virus Shedding
Interventions: BIOLOGICAL: Live attenuated influenza vaccine|OTHER: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome
Status: COMPLETED
Conditions: Severe Trauma|General Anaesthesia
Interventions: DIAGNOSTIC_TEST: PDEQ, PCL-5 and demographic survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Attenuating Cancer Treatment-related Toxicity in Oncology Patients With a Tailored Physical Exercise Program
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: OTHER: ATOPE-B|OTHER: ATOPE-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jointly Managing JIA Online: An Internet-based Psycho-educational Game for Children With JIA and Their Parents
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: BEHAVIORAL: Game|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of ZPL389 in Patients With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: ZPL389 3mg|DRUG: ZPL389 10mg|DRUG: ZPL389 30mg|DRUG: ZPL389 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Triple Combination Therapy With Dorzolamide Hydrochloride / Brimonidine Tartrate / Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Status: WITHDRAWN
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: dorzolamide hydrochloride 2.0%/brimonidine tartrate 0.2%/timolol 0.5% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Heart Rate Variability in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Acupuncture Active|OTHER: Acupuncture Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
Status: UNKNOWN
Conditions: Tooth Loss|Recession, Gingival
Interventions: PROCEDURE: Test - Implant with L-PRF|PROCEDURE: Control - Implant without L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Angioplasty by the Chocolate PTA Balloon Catheter Compared to Conventional PTA Balloons Via OCT Imaging
Status: WITHDRAWN
Conditions: Infrainguinal Peripheral Arterial Disease
Interventions: DEVICE: Chocolate PTA Balloon Angioplasty|DEVICE: Standard PTA Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Growing Biofilm by an Antiplaque Mouthrinse
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: mouthrinse (Grape Seed Extract + nicomethanol fluorhydrate)|OTHER: mouthrinse containing non-active component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Status: COMPLETED
Conditions: Surgery|Surgery--Complications|Neurological Morbidity|Neurological Diseases or Conditions|Neurological Disorder|Neurological Complication|Neurological Procedural Complication|Outcome, Fatal|Comorbidities and Coexisting Conditions|Morality
Interventions: PROCEDURE: Neurosurgical procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: LAL (Light Adjustable Lens) and Light Deliver Device (LDD)|DEVICE: Monofocal control IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Capsule Endoscopy in Children
Status: COMPLETED
Conditions: Portal Hypertension|Cirrhosis
Interventions: DEVICE: Wireless esophageal capsule endoscopy ( PillCam Eso2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.
Status: RECRUITING
Conditions: Frailty|Oncology Problem|Cognitive Impairment
Interventions: OTHER: Geriatric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Northwest Therapies Trauma Psilocybin Study Compassionate Use Study
Status: NOT_YET_RECRUITING
Conditions: Trauma, Nervous System
Interventions: DRUG: Trauma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Erythropoietin at the Time of Reperfusion in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: human recombinant erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Investigative MRI Protocol
Status: UNKNOWN
Conditions: Multiple MRI Exams, Including|Cardiac|Abdominal|Lumbar|Neck|Pelvis
Interventions: DEVICE: 16 Channel SPEEDER Flex Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate Safety and Tolerability of PF-07242813 in Healthy Participants and Participants With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PF-07242813|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Cisplatin + Pemetrexed + Avastin as First-Line Therapy
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating if Interferon-Beta Can be Used in Patients With MS After They Have Developed Neutralizing Antibodies
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Interferon-beta-1a|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Alzheimer's Disease Treatment
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: Active Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
Status: TERMINATED
Conditions: Gastric Neoplasm
Interventions: PROCEDURE: Surgery: abdominal and transhiatal approach|PROCEDURE: Surgery: left thoraco-abdominal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Training Via Teleconference
Status: RECRUITING
Conditions: Hearing Impairment, Sensorineural|Auditory; Nerve|Cochlear Implants|Rehabilitation
Interventions: OTHER: Teleconferencing|OTHER: Auditory training services
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Insulin-Only Bionic Pancreas Bridging Study
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: iLet Bionic Pancreas insulin-only configuration with Humalog or Novolog|DRUG: iLet Bionic Pancreas insulin-only configuration with Fiasp|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FRUVEDomics: Behavioral Intervention in Young Adults to Identify Metabolomics and Microbiome Risk
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: FRUVEDomics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of Infliximab (Remicade) in Subjects With Fistulizing Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: infliximab or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression
Status: COMPLETED
Conditions: Depressive Disorder, Treatment-Resistant|Depressive Disorder, Major|Unipolar Depression|Depression, Bipolar
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Truncal Blocks for Pediatric With Developmental Dysplasia of the Hip Undergoing Open Reduction
Status: COMPLETED
Conditions: Developmental Dysplasia of the Hip (DDH)
Interventions: PROCEDURE: transversalis fascia plane block|PROCEDURE: quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARREST PAD (Peripheral Arterial Disease)
Status: COMPLETED
Conditions: Arterial Occlusive Disease|Intermittent Claudication|Insulin Resistance
Interventions: DRUG: atorvastatin and pioglitazone|DRUG: atorvastatin/placebo|DRUG: pioglitazone/placebo|DRUG: placebo/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial to Assess Efficacy and Safety of Cetuximab for the Treatment of Chinese Participants With Head and Neck Cancer
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Cetuximab|DRUG: Cisplatin/Carboplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of All Ceramic Single-retainer Using Upper Canine as Abutment With Minimum Preparation on the Lingual Surface, to Replace the Upper Lateral Incisor and Will be Compared With the All Ceramic Single-retainer Using Upper Central Incisor.
Status: NOT_YET_RECRUITING
Conditions: Survival, Prosthesis
Interventions: PROCEDURE: all ceramic single-retainer resin bonded fixed partial denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Impact of Menthol Ban in Cigarettes and E-cigarettes
Status: RECRUITING
Conditions: Tobacco Smoking
Interventions: BEHAVIORAL: menthol ban in cigarettes only|BEHAVIORAL: total menthol ban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Ketamine|DRUG: isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adenoid Cystic Carcinoma and Carbon Ion Only Irradiation
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma
Interventions: RADIATION: Carbon ion irradiation|RADIATION: Bimodal irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Habitual Wearers of Avaira Toric When Refitted With Clariti Toric Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: somofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Proof of Concept Study With an Endothelin Receptor B Inhibitor (BQ-788) for Human Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Endothelin Receptor B inhibitor BQ788|DRUG: PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 3 Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)
Status: COMPLETED
Conditions: Myasthenia Gravis|Myasthenia Gravis, Juvenile Form|Myasthenia Gravis, Generalized
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Extragonadal Germ Cell Tumor|Ovarian Cancer|Teratoma|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT