pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PROcalcitonin and Presepsin-guided Decision for Antibiotic Prophylaxis of EOS
Status: NOT_YET_RECRUITING
Conditions: Early-Onset Neonatal Sepsis
Interventions: PROCEDURE: Procalcitonin/Presepsin guided antibiotic prophylaxis for EOS|PROCEDURE: Antibiotic prophylaxis for EOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anlotinib Combined With Niraparib Dual Therapy in Platinum-resistant Recurrent Ovarian Clear Cell Carcinoma.
Status: COMPLETED
Conditions: Platinum-resistant Recurrent Clear Cell Ovarian Cancer
Interventions: DRUG: Niraparib|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals
Status: ACTIVE_NOT_RECRUITING
Conditions: Helicobacter Pylori Infection|Atrophic Gastritis|Intestinal Metaplasia|Low Grade Intraepithelial Neoplasia|High Grade Intraepithelial Neoplasia|Early Gastric Cancer|Gastric Cancer
Interventions: OTHER: AI recongnize disease and generate recommendations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: C04.588.274.476.411.307
Interventions: DRUG: Oxaliplatin (Eloxatin)|DRUG: Capecitabine (Xeloda)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy
Status: COMPLETED
Conditions: Knee Arthritis
Interventions: DRUG: prilocaine|DRUG: mepivacaine|PROCEDURE: Sciatic-femoral Nerve Block|PROCEDURE: Spinal anesthesia|DEVICE: Sonoplex, Pajunk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Options for Second-Line Effective Combination Therapy (SELECT)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Lopinavir/ritonavir|DRUG: Raltegravir|DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Abacavir/lamivudine/zidovudine|DRUG: Abacavir/lamivudine|DRUG: Lamivudine/zidovudine|DRUG: Abacavir|DRUG: Zidovudine|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Infertility by Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchyma Stem Cells
Status: COMPLETED
Conditions: Infertility|Intrauterine Adhesions
Interventions: PROCEDURE: UC-MSCs therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Recurrent Neuroblastoma
Interventions: BIOLOGICAL: hu14.18-IL2 fusion protein|DRUG: isotretinoin|BIOLOGICAL: sargramostim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Macular Edema|Diabetic Retinopathy
Interventions: DRUG: MS-R001 (rapamycin)|DRUG: MS-R001 (rapamycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Patients With Thoraco-abdominal Injury and Stress-induced Hyperglycemia or Diabetic Hyperglycemia
Status: COMPLETED
Conditions: Abdominal Injury|Thoracic Injury|Hyperglycemia|Hyperglycemia Stress
Interventions: OTHER: Stress-induced hyperglycemia|OTHER: Diabetic hyperglycemia|OTHER: Diabetic normoglycemia|OTHER: Non-diabetic normoglycemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rapid Sequence Induction: Succinyl Choline vs Rocuronium After Pretreatment With Dexmedetomidine
Status: UNKNOWN
Conditions: Rapid Sequence Induction
Interventions: DRUG: dexemedetomidine and rocuronium|DRUG: 0.9% saline and succinyl choline 1mg/ kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison Between Three Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Ceaserian Section for Patients With Preeclampsia
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect|Cesarean Section Complications
Interventions: DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-Punch Biopsy Bleeding in Apixaban-Treated Patients Using Self-Administered BXP154B
Status: COMPLETED
Conditions: Wound Bleeding
Interventions: DRUG: BXP154B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postmenopausal Women,Treatment of Sleep Apnea and Co-morbidities
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DRUG: medroxyprogesterone acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert
Status: COMPLETED
Conditions: Primary Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Fenretinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Safety of Vorapaxar in Japanese Subjects With Cerebral Infarction (P05005; MK-5348-017)
Status: COMPLETED
Conditions: Cerebral Infarction
Interventions: DRUG: Vorapaxar 2.5 mg|DRUG: Vorapaxar 1 mg|DRUG: Placebo|DRUG: Aspirin 75-150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Extension Study of Duvelisib and Ofatumumab in Participants With CLL/SLL Previously Enrolled in Study IPI-145-07
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: IPI-145|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Dementia|Amnestic Mild Cognitive Impairment - aMCI
Interventions: DEVICE: NeuroElectric StarStim|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ORN Study: Curative Treatment of Osteoradionecrosis (ORN) With Hybrid Bone Substitution
Status: COMPLETED
Conditions: Mandible|Osteoradionecrosis
Interventions: PROCEDURE: Hybrid bone substitution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reconstruction
Status: NOT_YET_RECRUITING
Conditions: ACL Injury|ACL Sprain|ACL Tear|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Injuries
Interventions: DEVICE: Isoinertial training|OTHER: Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass-Drug Administration to Reduce Malaria Transmission
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Sulphadoxine-pyrimethamine (day 1: 500mg S&25mg P/20 kg)|DRUG: Artesunate (day 1,2,3: 4 mg/kg)|DRUG: Primaquine-base (day 3: 0.75 mg/kg)|DRUG: placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Response To Oral Agents in Diabetes (ROAD)- Pilot Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Gliclazide MR|DRUG: Sitagliptin|DRUG: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction With Misoprostol: Oral Mucosa Versus Vaginal Epithelium (IMPROVE)
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: misoprostol/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Family Based Prevention of Alcohol and Risky Sex for Older Teens
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Intoxication|Alcohol Poison|Alcohol-Related Disorders|Alcohol Impairment|Alcohol Withdrawal|Alcohol Abstinence|Alcohol; Harmful Use|Sex Behavior|Sexual Aggression|Sexual Harassment|Relation, Interpersonal
Interventions: BEHAVIORAL: Smart Choices 4 Teens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Live Versus Inactivated Influenza Vaccine Study in Hutterite Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent Inactivated Vaccine|BIOLOGICAL: Live Attenuated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of the Longeviti ClearFit Implant in Craniectomies for Post-Operative Monitoring in Chronic Subdural Hematomas
Status: NOT_YET_RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: DEVICE: ClearFit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BAY1830839: First in Man, Single Dose Escalation, Safety & Tolerability and Pharmacokinetics
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: BAY1830839|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Perlane-L in the Correction of Midface Volume Deficit
Status: UNKNOWN
Conditions: Facial Volume
Interventions: DEVICE: Perlane-L|OTHER: Non-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Euglycemic Insulin Clamp Study in Type 1 Diabetic Patients With Oral Insulin (ORAMED)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: ORMD-0801 capsules- 2x8mg|DRUG: ORMD-0801 capsules- 3x8mg|DRUG: ORMD-0801 capsules- 1x16mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of Small DNA Virus Encoded Oncogenes in Viral Carcinogenesis Using Laboratory Model Systems
Status: UNKNOWN
Conditions: DNA Virus Infections
Interventions: GENETIC: HPV oncogenes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy With Sildenafil Plus Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: sildenafil|DRUG: placebo|DRUG: paclitaxel (taxol)|DRUG: carboplatin (palaplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rivoceranib and Trifluridine/Tipiracil for Metastatic Colorectal Cancer (mCRC)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Rivoceranib|DRUG: Trifluridine/Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted TKA
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: PROCEDURE: Total knee replacement using Omnibot Knee System|PROCEDURE: Conventional Total knee replacement|DEVICE: Omnibot Robotic Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Continued Bevacizumab Plus Chemotherapy Until First Progression in Participants With Metastatic Colorectal Cancer (CRC)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Bevacizumab|COMBINATION_PRODUCT: Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pimecrolimus Cream 1% in Adult Patients With Perioral Dermatitis
Status: COMPLETED
Conditions: Perioral Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
Status: RECRUITING
Conditions: Metastatic Leiomyosarcoma|Metastatic Sarcoma|Metastatic Soft Tissue Sarcoma|Unresectable Leiomyosarcoma|Unresectable Sarcoma|Unresectable Soft Tissue Sarcoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|DRUG: Peposertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Prophylaxis Versus Pre-emptive Therapy With Posaconazole Post-Lung Transplant
Status: UNKNOWN
Conditions: Fungal Infection
Interventions: OTHER: Universal Posaconazole Prophylaxis|OTHER: Pre-emptive Posaconazole Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Neo-adjuvant Chemoradiotherapy Followed by Minimally Invasive Esophagectomy for Squamous Cell Esophageal Cancer
Status: UNKNOWN
Conditions: Squamous Cell Esophageal Carcinoma
Interventions: PROCEDURE: Neo-adjuvant Chemoradiotherapy followed by Mckeown MIE|DRUG: Cisplatin|DEVICE: Mckeown MIE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain
Status: RECRUITING
Conditions: Cervicogenic Headache|Occipital Neuralgia
Interventions: DEVICE: SPRINT Peripheral Nerve Stimulation (PNS) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Development for Glucose Transporter Type I Deficiency Syndrome (G1D)
Status: COMPLETED
Conditions: Glucose Transporter Type 1 Deficiency Syndrome|GLUT1 Deficiency Syndrome
Interventions: DRUG: Triheptanoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Analyze the Occurrence of Transformation From Myelodysplastic Syndrome to Acute Myeloid Leukemia in Patients With Myelodysplastic Syndrome Who Received Revlimid® 5 mg Capsules and Who Are Continuing or no Longer Continuing Revlimid Treatment
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myeloid, Acute
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Microwave Ablation With Splenic Artery Occlusion for Secondary Hypersplenism
Status: RECRUITING
Conditions: Secondary Hypersplenism
Interventions: PROCEDURE: microwave ablation of the spleen|OTHER: Splenic artery balloon implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Long-term Immunogenicity and Safety of a Human Papillomavirus (HPV) Vaccine in Healthy Female Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: PROCEDURE: Blood sampling|PROCEDURE: Cervico-vaginal secretion (CVS) samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419
Status: COMPLETED
Conditions: Peripheral Neuropathic Pain
Interventions: DRUG: SR419|DRUG: active control|DRUG: SR419 placebo|DRUG: active control placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post Market Clinical Follow-up Study of IrisFITTM PFO (Patent Foramen Ovale) Occluder
Status: COMPLETED
Conditions: Patent Foramen Ovale
Interventions: DEVICE: IrisFIT PFO Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study to Investigate Co-administration of GW642444M With Ketoconazole
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Ketoconazole + GW642444M|DRUG: Placebo + GW642444M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia Alzheimers|Dementia, Mild
Interventions: BIOLOGICAL: ALZ-101|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Combination of Mindfulness and Buteyko Techniques for the Improvement of Poorly Controlled Asthma.
Status: RECRUITING
Conditions: Asthma|Anxiety|Stress
Interventions: OTHER: Mindfulness and Buteyko techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcutaneous Tibial Nerve Stimulation in Antimuscarinic Naive and Refractory Women With Idiopathic Overactive Bladder
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder, Overactive
Interventions: OTHER: Transcutaneous tibial nerve stimulation (TTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using a Closed-loop System for Oxygen Delivery (FreeO2) to Optimize Oxygentherapy in Patients With COPD Exacerbation
Status: UNKNOWN
Conditions: COPD Exacerbation
Interventions: DEVICE: Automated settings on the oxygen delivery device|DEVICE: Manual settings with FreeO2 system in collection mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: NATURAL KILLER CELLS IN IMMUNOLOGIC THROMBOCYTOPENIC PURpura of Adults
Status: COMPLETED
Conditions: Immunologic Thrombcytopenic Purpura (ITP) Adults
Interventions: OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Status: COMPLETED
Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy|Autonomic Failure
Interventions: OTHER: Passive heat stress|OTHER: Control (non-heating)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects
Status: COMPLETED
Conditions: Brain Injury|Sequelae|Stroke|Anoxia|Trauma
Interventions: PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Computed Tomography Angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Cervical Spine Mobilization on Lateral Epicondylitis
Status: RECRUITING
Conditions: Lateral Epicondylitis
Interventions: OTHER: SNAGs - eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Colistin Monotherapy Versus Colistin Plus Minocycline for Carbapenem-Resistant A. Baumannii Infection
Status: RECRUITING
Conditions: Acinetobacter Infections
Interventions: DRUG: Colistin|DRUG: Minocycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Effectiveness of Sodium Fluoride Varnish in Prevention of Dental Caries in School Children
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: DRUG: 5% sodium fluoride varnish|OTHER: WATER ON TEETH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iatrogenic Impairment of Urethral Coitus Owing to Midurethral Sling Procedure in a Woman With Vaginal Agenesis.
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Vaginal Agenesis
Interventions: PROCEDURE: Cut the sling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Loperamide Hydrochloride 2 mg and Simethicone 125 mg Tablet Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Loperamide HCl 2 mg and simethicone 125 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Coronary Flow Reserve Evaluation in PET and in MRI Scanner in Heart Transplanted Patients : Comparison With Multi-detectors Scanner
Status: UNKNOWN
Conditions: Heart Disease
Interventions: RADIATION: 15O-H2O PET -|RADIATION: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibacterial Effect of Probiotic Yogurt Compared to Xylitol
Status: UNKNOWN
Conditions: Geriatric Patients
Interventions: DIETARY_SUPPLEMENT: Probiotic yogurt|DIETARY_SUPPLEMENT: xylitol chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteria
Status: COMPLETED
Conditions: Peripheral Spondylarthritis
Interventions: DRUG: Placebo|DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exercises in Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: body awareness therapy|OTHER: core stabilization exercises|OTHER: traditional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Lipodystrophy
Interventions: DRUG: Placebo|DRUG: Low-Dose REGN4461|DRUG: High-dose REGN4461
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: PPC|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Activity of Bioactive Natural Compounds as Potential Agonists of GLP1R
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Jubanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Nasacort® Nasal Spray in Comparison With Flixonase® Nasal Spray in Adults Suffering From Perennial Allergic Rhinitis (PAR)
Status: COMPLETED
Conditions: Rhinitis Allergic
Interventions: DRUG: triamcinolone XRG5029|DRUG: fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Stenting and Coronary Bypass Grafting at the Same Time in a Specialty Built Operating Room
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Robotic-assisted Coronary Surgical Revascularization|PROCEDURE: PCI- Drug Eluting Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain
Status: COMPLETED
Conditions: Pain|Postoperative Pain|Pain, Acute
Interventions: DRUG: MR-107A-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for Post Traumatic Headache
Status: RECRUITING
Conditions: Post-Traumatic Headache
Interventions: DRUG: Dexamethasone|DRUG: Metoclopramide 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Darbepoetin Alfa in Subjects With Chronic Kidney Disease (CKD) Receiving Dialysis
Status: COMPLETED
Conditions: Kidney Disease|Chronic Kidney Disease
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Tezepelumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis.
Status: COMPLETED
Conditions: Chronic Rhinosinusitis With Polyposis
Interventions: DRUG: budesonide|DRUG: budesonide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bridges to the Future: Economic Empowerment for AIDS-Orphaned Children in Uganda
Status: COMPLETED
Conditions: Poverty|Orphaned Children|AIDS Orphans
Interventions: BEHAVIORAL: Bridges|BEHAVIORAL: Bridges PLUS|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lenalidomide and Dexamethasone for Treatment of Patients With Acute Myeloma (Light Chain)-Induced Renal Failure
Status: UNKNOWN
Conditions: Multiple Myeloma Light Chain Induced Renal Insufficiency
Interventions: DRUG: lenalidomide plus dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: EDP-235|DRUG: Midazolam|DRUG: Rosuvastatin|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Accelerated Theta Burst Stimulation in Treatment of Patients With Bipolar Depression and Suicidality
Status: RECRUITING
Conditions: Bipolar Depression
Interventions: DEVICE: Transcranial Magnetic Stimulation MagPro R30 with the MCF-B70 figure-of-eight coil (MagVenture, Denmark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used
Status: RECRUITING
Conditions: Colonoscopy|Polyp of Colon
Interventions: DEVICE: CAP-straight|DEVICE: CAP-daisy|OTHER: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effectiveness of Antibacterial Therapeutic Clothing Based on Silver or Chitosan as Compared With Non-antibacterial Therapeutic Clothing in Patients With Moderate to Severe Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DEVICE: DermaCura® Chitosan based antimicrobial therapeutic clothing|DEVICE: Binamed® silver based antimicrobial therapeutic clothing|DEVICE: Binamed® therapeutic clothing without antimicrobial agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study II on Remote Ischemic Preconditioning for the Prevention of Stroke-Associated Pneumonia
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group A ) A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Bone Resorption
Interventions: PROCEDURE: Drilling at low speed|PROCEDURE: Conventional drilling at high speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PMT for MDRO Decolonization
Status: RECRUITING
Conditions: Multidrug Resistant Bacterial Infection|Enterobacteriaceae Infections|Pseudomonas Aeruginosa|VRE Infection|Methicillin-resistant Staphylococcus Aureus
Interventions: DRUG: PMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Dry Foot Skin Between Diabetic and Non-diabetic Subjects and the Effects of Two Cosmetic Foot Care Products
Status: COMPLETED
Conditions: Xerosis Cutis
Interventions: OTHER: 10% Urea foot lotion|OTHER: 10% Urea foot ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Idiopathic Pulmonary Fibrosis (IPF) and the 3 Minutes Sit-to-stand Test
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DIAGNOSTIC_TEST: 3 minutes sit-to-stand test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction
Status: COMPLETED
Conditions: Chronic Eustachian Tube Dysfunction|Chronic Recurrent Otitis Media|Effusion After Tympanostomy
Interventions: DEVICE: Eustachian tube dilatation device|PROCEDURE: Myringotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randonmized Comparison of Needlescopic Versus Conventional Laparoscopic Adrenalectomy
Status: UNKNOWN
Conditions: Adrenal Tumors
Interventions: PROCEDURE: needlescopic adrenalectomy and laparoscopic adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic (PK) Study of Oral Bendavia Administered for 7 Days
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Bendavia 10mg|DRUG: Bendavia 50mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome (MDS)|Hematopoietic Stem Cell Transplant (HSCT)
Interventions: DRUG: Reduced-Intensity Conditioning Regimen|DRUG: Myeloablative Conditioning Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Response and Safety Following FMT for UC
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Fecal Microbiota Transplantation
Interventions: OTHER: FMT through a naso-jejunal tube|OTHER: FMT through TET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RZ358 Treatment for Congenital Hyperinsulinism
Status: RECRUITING
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: RZ358 (5 mg/kg) + SOC (Standard-of-Care) or Placebo + SOC|DRUG: RZ358 (10 mg/kg) or Placebo + SOC|DRUG: RZ358 (5-10 mg/kg) + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis.
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled Sodium Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Mindfulness Program (MBSR) in the Management of Symptomatic Hip and Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Mindfulness|MBSR
Interventions: OTHER: Mindfluness and usual care|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decitabine in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Bladder Cancer|Recurrent Breast Cancer|Recurrent Melanoma|Stage III Melanoma|Stage IV Bladder Cancer|Stage IV Breast Cancer|Stage IV Melanoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: decitabine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Quadratus Lumborum, Paravertebral Blocks
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus Lumborum Block II|DRUG: Patient controlled intravenous analgesia|PROCEDURE: Quadratus Lumborum Block III|DRUG: Patient controlled intravenous analgesia|PROCEDURE: Paravertebral Block|DRUG: Patient controlled intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Topically-Applied Hyaluronic-Acid on Palatal Epithelial Wound Closure
Status: COMPLETED
Conditions: Wound Healing Complication
Interventions: DRUG: Periodontal dressing material|DRUG: 0.2% Hyaluronic acid gel|DRUG: 0.8% Hyaluronic acid gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Enamel Abrasion and Stain Removal Efficacy
Status: NOT_YET_RECRUITING
Conditions: Abrasion|Discoloration, Tooth
Interventions: OTHER: Charcoal -based whitening toothpaste|OTHER: Calcium carbonate /perlite containing whitening toothpaste.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications
Status: COMPLETED
Conditions: Surgery, Oral|Hemorrhage|Postoperative Complications|Oral Surgical Procedures|Anticoagulants Causing Adverse Effects in Therapeutic Use|Anticoagulant-induced Bleeding
Interventions: PROCEDURE: Type of surgery|DRUG: Dabigatran|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Edoxaban|DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury|Cerebral Edema
Interventions: DRUG: ABX-101 1mg|DRUG: ABX-101 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Cytarabine, Leucovorin, Methotrexate, Procarbazine, Rituximab, Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Initiation of Feeding in Preterm Newborns With Prenatal AREDF in Umbilical Artery
Status: COMPLETED
Conditions: Time for Achievement of Full Feeds
Interventions: OTHER: Early Enteral feeding|OTHER: Late enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Preoperative Gabapentine for Carpal Tunnel
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Gabapentine|OTHER: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bringing Care to Patients: Patient-Centered Medical Home for Kidney Disease
Status: COMPLETED
Conditions: ESRD
Interventions: OTHER: Patient-Centered Medical Home for Kidney Disease (PCMH-KD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: JNJ-77242113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Determine if Beta Glucan Reduces the Incidence, Duration or Severity of URTIs Among Skiers
Status: RECRUITING
Conditions: Upper Respiratory Tract Infections|Mental Stress
Interventions: DIETARY_SUPPLEMENT: Treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: This Study Will Investigate the Safety, Tolerability and Pharmacokinetic Profile of Repeat Oral Doses of GSK2140944 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: GSK2140944|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Enzalutamide in Chemotherapy-Naïve, Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole-Body Vibration Exercise on Serum IGF-1 in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Hormonal Responses to Exercise in Patients With Fibromyalgia.
Interventions: DEVICE: Vibratory platform, PowerPlate®, Badhoevendorp, Netherlands|DEVICE: Placebo Whole-body vibration exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lacidipine and Amlodipine on Blood Pressure in Korean ISH Patients Aged 60 to 80 Years
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Lacidipine & Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of QY201 Tablet in Subjects With Moderate to Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: 2mg QY201 tablets or 2mg QY201 placebo,BID|DRUG: 5mg QY201 tablets or 5mg QY201 placebo,BID|DRUG: 10mg QY201 tablets or 10mg QY201 placebo,QD|DRUG: 10mg QY201 tablets or 10mg QY201 placebo,BID|DRUG: 15mg QY201 tablets or 15mg QY201 placebo,BID|DRUG: 20mg QY201 tablets or 20mg QY201 placebo,BID|DRUG: 5mg QY201 tablets，BID|DRUG: 10mg QY201 tablets，BID|DRUG: 20mg QY201 tablets，BID|DRUG: QY201 placebo，BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Remote Limb Ischemic Preconditioning on Acute Cerebral Infarction
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: RIPC group|DEVICE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunocompromised|Hematologic Malignancy|Post Hematopoietic Stem Cell Transplant|Hypoxia|Pulmonary Infiltrates
Interventions: DEVICE: High Flow Nasal Cannula or Low Flow Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Follow-up Study of Inhaled Iloprost in Patients With Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Ventavis (Iloprost, BAYQ6256)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NABOTA in Treatment of Essential Blepharospasm
Status: COMPLETED
Conditions: Blepharospasm
Interventions: DRUG: Clostridium Botulinum Toxin Type A|DRUG: Clostridium Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449) in Operable Basal Cell Carcinoma
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy
Status: UNKNOWN
Conditions: Roux-en-Y Gastric Bypass|Cholecystitis; Gallstone|Gallbladder Diseases
Interventions: PROCEDURE: Robotic gastric bypass with or without cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Building Outcomes With Observation-Based Supervision: An FFT Effectiveness Trial
Status: COMPLETED
Conditions: Delinquency|Substance Abuse|Self Destructive Behavior
Interventions: BEHAVIORAL: Supervision|BEHAVIORAL: Observational Supervision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: Sitagliptin (MK0431)|DRUG: Placebo/Glipizide 5 mg|DRUG: Metformin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Galnobax® for the Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Esmolol hydrochloride|DRUG: Esmolol hydrochloride|DRUG: Esmolol hydrochloride|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT