pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Status: COMPLETED
Conditions: Radiculopathy|Sciatica
Interventions: DRUG: VVZ-149|DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation Optimisation Strategy (S.O.S.) Ventilation
Status: COMPLETED
Conditions: Surgery|Critical Illness|Mechanical Ventilation Complication|Organ Dysfunction Syndrome|Intensive Care Unit Syndrome
Interventions: OTHER: Therapy strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Apatinib|DRUG: fluorouracil and platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Brentuximab Vedotin in Relapsed/Refractory Peripheral T-Cell Lymphoma Expressing CD30
Status: TERMINATED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: Brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: KH631
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Lung Function Profile of Inhaled Tiotropium + Olodaterol Fixed Dose Combination Compared to Fluticasone Propionate + Salmeterol Fixed Dose Combination in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate|DRUG: salmeterol|DRUG: placebo|DRUG: placebo|DRUG: tiotropium|DRUG: olodaterol|DRUG: olodaterol|DRUG: placebo|DRUG: placebo|DRUG: tiotropium|DRUG: fluticasone propionate|DRUG: salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Post-thrombotic Syndrome
Interventions: DEVICE: EkoSonic® Endovascular System|BIOLOGICAL: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Sleep Apnea|Chronic Nasal Congestion
Interventions: DRUG: Oxymetazoline Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study on Budesonide/Formoterol Device-metered Dry Powder Inhalers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Symbicort Turbohaler|DRUG: Budesonide/formoterol Easyhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Sustainable Future Proteins
Status: COMPLETED
Conditions: Intestinal Barrier Function|Protein Digestion Kinetics
Interventions: DIETARY_SUPPLEMENT: Corn protein powder|DIETARY_SUPPLEMENT: Bovine plasma protein powder|DIETARY_SUPPLEMENT: Whey protein powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bunionectomy Study for Postoperative Analgesia (EPOCH 1)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: HTX-011|DRUG: Saline Placebo|DRUG: Bupivacaine HCl|DEVICE: Luer-lock applicator|DEVICE: Vial access device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Preparation in Self-Hypnosis by Anchoring Versus Conversational Hypnosis, Used Alone or Combined, in Patients Undergoing Breast Macrobiopsies
Status: RECRUITING
Conditions: Breast Neoplasm Female
Interventions: BEHAVIORAL: Preparation in Self-Hypnosis by anchoring|BEHAVIORAL: Conversational Hypnosis|BEHAVIORAL: Preparation in Self-Hypnosis by anchoring + Conversational Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Relationship of Nocturnal Concentrations of Melatonin, γ-aminobutyric Acid and Total Antioxidants With Insomnia
Status: UNKNOWN
Conditions: Insomnia
Interventions: OTHER: insomnia group|OTHER: non-insomnia group|OTHER: normal control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Waldenstr(SqrRoot)(Delta)m s Macroglobulinemia|Mantle Cell Lymphoma|Sudden Cardiac Death|Cardiac Arrhythmias|Hematologic Malignancies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study Evaluation of 2 Artificial Tears. Evaluation of TBUT, Tear Meniscus Height and Tear Thickness
Status: COMPLETED
Conditions: Tear Film Thickness
Interventions: DRUG: Refresh Tears, 9582X
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Obesity|Overweight and Obesity|Adolescent Obesity|Adolescent Overweight|Diabetes
Interventions: DIETARY_SUPPLEMENT: Diet high on protein (25E%/day)|OTHER: Increased follow-up contact after attending a weight loss camp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cut Down on Carbohydrate Usage in the Diet of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Carbohydrate-Restricted Diet|DIETARY_SUPPLEMENT: Standard Antidiabetic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Individuals With Spinal Cord Injury: A Pilot Study
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Automatic Defibrillator Implantation Trial - Chemotherapy-Induced Cardiomyopathy
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: DEVICE: Three-lead CRT-D (Defibrillator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C11 AMT Positron Emission Tomography (PET) Imaging in Patients With Metastatic Invasive Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Adenovirus-p53 transduced dendritic cell vaccine|DRUG: 1-methyl-D-tryptophan|RADIATION: Carbon C 11 alpha-methyltryptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing the Safety and Effectiveness of Topiramate With the Safety and Effectiveness of Amitriptyline in Preventing Migraine Headaches
Status: COMPLETED
Conditions: Migraine|Headache
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Fasting Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Normal Healthy Subjects
Status: COMPLETED
Conditions: Therapeutic Equivalency
Interventions: DRUG: Pravastatin|DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of the Dosage Regimen of Growth Hormone Therapy in Children Born Small for Gestational Age
Status: COMPLETED
Conditions: Small Gestational Age (SGA)
Interventions: DRUG: Saizen®|DRUG: Saizen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Moderately Hypofractionated RT vs. Ultra-hypofractionated Focal Lesion Ablative Microboost in Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiotherapy standard|RADIATION: Radiotherapy Hypo-FLAME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Data Exchange to Improve Medication Safety
Status: COMPLETED
Conditions: Drug Toxicity
Interventions: OTHER: HIE-Enhanced Medication Reconciliation|OTHER: Optimal Medication Reconciliation without HIE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Volume Effect of Nerve Hydrodissection for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Ultrasound-guided nerve hydrodissection|PROCEDURE: Ultrasound-guided nerve hydrodissection|DEVICE: Ultrasound|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation for Young People
Status: RECRUITING
Conditions: Congenital Heart Disease|Cardiomyopathies|Cardiac Arrythmias|Heart Failure|Cerebrovascular Event|Heart Valve Diseases
Interventions: BEHAVIORAL: Cardiac Rehabilitation (CR): Experimental|BEHAVIORAL: Treatment as usual: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Levosimendan|DRUG: Placebo for levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Opioid Optimization of Dosing and Selections (GOODS) Study
Status: COMPLETED
Conditions: Perioperative/Postoperative Complications
Interventions: OTHER: Pharmacogenomic (PGx)|OTHER: Review results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Reproxalap Ophthalmic Solution (0.5%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anrotinib Hydrochloride Combined With Adriamycin for Neoadjuvant Treatment of High-grade Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Anrotinib hydrochloride combined with adriamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXA vs. Amicar in Total Knee and Hip Arthroplasty
Status: COMPLETED
Conditions: Blood Loss|Hip Arthritis|Knee Arthritis
Interventions: DRUG: Amicar|DRUG: TXA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Phytotherapy in SARS-COV2(COVID-19)
Status: COMPLETED
Conditions: a Randomized Double-blind Study|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)|PHYTOTHERAPIE
Interventions: DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|ALL, Childhood|ALL
Interventions: DRUG: Ruxolitinib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Mercaptopurine|DRUG: Vincristine|DRUG: Pegaspargase|DRUG: Rituximab|DRUG: Methotrexate (Intrathecal Administration)|DRUG: Methotrexate (Intravenous Administration)|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Thioguanine|DRUG: Methotrexate Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic, Neurophysiological and Psychological Predictive Factors of Chronic Neuropathic Pain After Surgery for Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: GENETIC: Genetical analyses|OTHER: Chronic pain identification questionnaires|OTHER: Neurophysiological and psychophysical evaluations|OTHER: Quality of life questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety and Tolerability of Two Doses of Rilonacept in Pediatric Subjects With Active Systemic Juvenile Idiopathic Arthritis (SJIA)
Status: COMPLETED
Conditions: Systemic Juvenile Idiopathic Arthritis
Interventions: DRUG: rilonacept (IL-1 Trap)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Trial of Two Reminder/Recall Methods to Increase Immunization Rates in Young Children
Status: COMPLETED
Conditions: Immunization Rates
Interventions: BEHAVIORAL: Collaborative Pop-Based R/R: Phone/Mail Group|BEHAVIORAL: Collaborative Pop-Based R/R: Mail-Only Group|BEHAVIORAL: Practice-based Recall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Ezetimibe Add-On to Statin Therapy on Adipokine Production in Obese and Metabolic Syndrome Patients With Atherosclerosis
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Coronary Artery Disease
Interventions: DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiomics and Metabolomics in the Follow-up of CAR T-cells for Refractory or Relapsed Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Refractory or Relapsed Non-Hodgkin's Lymphoma
Interventions: OTHER: blood samples and 18FDG PET-CT exams
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1, SAD/MAD of Verasone™ Administered by Sinonasal Irrigation in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Verasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Treat Small Cell Lung Cancer With a Combination of Cisplatin, Pemetrexed, and Radiotherapy
Status: TERMINATED
Conditions: Small Cell Lung Cancer|Carcinoma, Small Cell|SCLC
Interventions: DRUG: pemetrexed|DRUG: cisplatin|RADIATION: radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-IL6 and Corticosteroid Monotherapy vs Combination in COVID-19
Status: UNKNOWN
Conditions: Critical Illness|Corona Virus Infection|Cytokine Release Syndrome
Interventions: DRUG: Interleukin 6 (IL6) Antagonist|DRUG: Interleukin 6 (IL6) Antagonist and corticosteroids|DRUG: corticosteroid alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep-brain Magnetic Stimulation (DMS) in the Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: High frequency stimulation|DEVICE: Low frequency stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of KBA1412 in Participants With Advanced Solid Malignant Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor Malignancy
Interventions: DRUG: KBA1412|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Hormonal Therapy Plus Palbociclib in Operable, Hormone Sensitive and HER2-Negative Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female|Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: DRUG: Palbociclib|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder
Status: COMPLETED
Conditions: Cocaine Addiction
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EXplanted LIver and Ex-vivo Pancreatic Specimen Evaluation by 7 TESLA MRI
Status: UNKNOWN
Conditions: Liver Cirrhosis|Liver Steatosis|Hepatocellular Carcinoma|Pancreatic Cancer|Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: 7T Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Acupuncture on Anti Mullerian Hormone and Assisted Reproduction Outcome in PCOS Patients Undergoing IVF
Status: COMPLETED
Conditions: PCOS
Interventions: DEVICE: Acupuncture(Hwato®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of BKvirus Nephropathy Risk by the NEPHROVIR Method in Kidney Transplant Patients With BKvirus Viremia
Status: ACTIVE_NOT_RECRUITING
Conditions: BK Virus Infection|Nephropathy|Kidney Transplantation
Interventions: BIOLOGICAL: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Oral Azacitidine (CC-486) in Combination With Pembrolizumab (MK-3475) in Patients With Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma and Other Malignant Neoplasms of Skin|Metastatic Melanoma
Interventions: DRUG: Azacitidine|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEP-701 (Lestaurtinib) in Myelofibrosis
Status: UNKNOWN
Conditions: Myelofibrosis|Essential Thrombocythemia|Polycythemia Vera
Interventions: DRUG: CEP-701 (Lestaurtinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tocilizumab in Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Involvement
Status: RECRUITING
Conditions: Giant Cell Arteritis|Neurovascular Disorder
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Docetaxel and Carboplatin in Late Relapse of Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Epithelial Cancer Recurrent
Interventions: DRUG: Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: prophylactic donor lymphocyte infusion (DLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Continous Suture With PDS Versus Interrupted Suture With Thread on Major Abdominal Incision
Status: COMPLETED
Conditions: Surgical Wound|Suture, Complication
Interventions: PROCEDURE: Mass continous suture with PDS|PROCEDURE: Interrupted suture with thread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MENOPUR in Gonadotrophin-releasing Hormone (GnRH) Antagonist Cycles With Single Embryo Transfer
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Highly purified menotrophin|DRUG: Recombinant FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time and Motion Related to PICC Insertion Process and Catheter Tip Confirmation
Status: COMPLETED
Conditions: Indication for PICC Placement
Interventions: DEVICE: Chest X-ray|DEVICE: Sherlock 3CG® TCS|PROCEDURE: Peripherally Inserted Central Catheter (PICC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: HSRT and IMRT Chemoradiotherapy for Newly Diagnosed GBM
Status: UNKNOWN
Conditions: Glioma, Malignant
Interventions: DEVICE: Radiation|DEVICE: Radiation|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National Institute of Diabetes and Digestive Kidney Diseases* Share Plus: Continuous Glucose Monitoring With Data Sharing in Older Adults With Type 1 Diabetes* and Their Care Partners to Improve Time in Range and Reduce Diabetes Distress.
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Share plus intervention|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Systemic Drugs on Intraocular Pressure
Status: UNKNOWN
Conditions: Glaucoma, Angle-Closure|Glaucoma Suspect|Glaucoma Secondary to Drugs, Bilateral|Hypertension
Interventions: DRUG: Antihypertensive Agents|DRUG: Antihistaminics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|OTHER: Laboratory Biomarker Analysis|DRUG: Pevonedistat|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: eMOTION Formative Study
Status: COMPLETED
Conditions: Physical Inactivity|Overweight or Obesity|Cancer
Interventions: BEHAVIORAL: Intensity-Based Goals|BEHAVIORAL: Affect-Based Goals|BEHAVIORAL: TYPE/CONTEXT Enhancement|BEHAVIORAL: SAVOR Enhancement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis Between the Results of Two Surgical Techniques of Orbital Decompression in Patients With Graves Orbitopathy
Status: COMPLETED
Conditions: Graves Ophthalmopathy
Interventions: PROCEDURE: Orbital decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Quantitative Imaging of Human Local Arterial Wall Elasticity Using Supersonic Shear Imaging
Status: COMPLETED
Conditions: Healthy Volunteers|Vascular Ehlers Danlos Syndrome
Interventions: OTHER: SSI and SphygmoCor® evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Learn How the Study Medicine (Ponsegromab) is Changed and Eliminated From Healthy Chinese Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ponsegromab|DRUG: Ponsegromab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Consumption of Yogurt Fortified in Calcium and Vit. D on Circulating Levels of 25OHD in Postmenopausal Women
Status: COMPLETED
Conditions: Menopause|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: CALIN+|DIETARY_SUPPLEMENT: CALIN+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Strength for U in Relationship Empowerment
Status: ACTIVE_NOT_RECRUITING
Conditions: IPV|Perinatal|Mental Health
Interventions: BEHAVIORAL: Strength for U in Relationship Empowerment (SURE)|BEHAVIORAL: Attention, time, and information matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Reno- and Vascular Protective Effect of a Vitamin-D-analogue in Moderate to Severe Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Zemplar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: 1: incretin-based therapy|OTHER: 2: other antidiabetic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Efficacy of Ultrasound Guided Erector Spinae Block for Modified Radical Mastectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: ultrasound guided erector spinae plan block using bupivacaine for modified radical mastectomy|PROCEDURE: ultrasound guided erector spinae plan block with bupivacaine and Dexmetonidine for modified radical mastectomy|PROCEDURE: ultrasound guided erector spinae plan block with bupivacaine and magnesium slphate for modified radical mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of the LOK® Robotic Gait Trainer in the Early Rehabilitation of Children After an Acquired Brain Injury (ABI)
Status: UNKNOWN
Conditions: Injury, Brain
Interventions: DEVICE: Lokomat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Food Trial to Evaluate the Safety and Tolerability of SBD111 in Health Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Medical Food: SBD111|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: GSK369796|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Trial of Safety and Tolerability of Oral Verdinexor (KPT-335) in Healthy Adults
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Verdinexor|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability of Beclomethasone Dipropionate/Formoterol Single Inhaler in Patients With Mild to Moderate Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fixed combination Beclomethasone Dipropionate/Formoterol HFA 134a-pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis|Pneumonia, Bacterial
Interventions: DRUG: Imipenem/Cilastatin/Relebactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Fluticasone Furoate Nasal Spray for 2 Weeks in Chinese Adult and Adolescent Subjects With Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Allergic Rhinitis
Interventions: DRUG: fluticasone furoate nasal spray|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iontophoresis in Psoriasis
Status: WITHDRAWN
Conditions: Psoriasis|Psoriasis Vulgaris|Skin Diseases
Interventions: DEVICE: Activapatch intellidose 2.5 using active Iontophoresis|DEVICE: Activapatch intellidose 2.5 using inactive Iontophoresis|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma
Status: RECRUITING
Conditions: DIPG
Interventions: DRUG: Bevacizumab Injection|RADIATION: Ultra-low-dose RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib and Fluzoparib With or Without Adebrelimab in Previously-treated TP53-mutant Advanced Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: NSCLC|Non-small Cell Lung Cancer
Interventions: DRUG: Apatinib + Fluzoparib|DRUG: Apatinib + Fluzoparib + Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Fluids After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Nausea|Postoperative Vomiting|Renal Function Abnormal|Hunger|Thirst|Fluid Electrolyte Disorders
Interventions: OTHER: Suspension of the IV fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPX-351 (Vyxeos™) for Transplant Eligible, Higher Risk Patients With Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: CPX-351|PROCEDURE: Research skin biopsy|PROCEDURE: Research blood draw|PROCEDURE: Research bone marrow aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Droxidopa for Fatigue in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease|Fatigue|Parkinsonism
Interventions: DRUG: Northera|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colorectal Cancer Detection by Means of Optical Fluoroscopy
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DEVICE: Optical Fluoroscopy|DEVICE: Optical Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Safety and Efficacy of FBPM10 System in the Treatment of Post-surgical Wounds
Status: COMPLETED
Conditions: Post-surgical Wounds
Interventions: DEVICE: FBPM10 System|OTHER: Massages with vitamin E cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasm
Interventions: DRUG: Ketoconazole|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiotherapy for Non-specific Neck Pain in Working Age Persons
Status: COMPLETED
Conditions: Neck Pain|Non-specific Neck Pain
Interventions: OTHER: Self-stretching exercise group|OTHER: Post-isometric relaxation exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Ease of Tracheal Intubation Using a McGrath MAC Laryngoscope and a Standard MacIntosh Laryngoscope
Status: COMPLETED
Conditions: Tracheal Intubation
Interventions: DEVICE: Laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Portable Mixed Reality-based Platform for Assessment of Progress in Multisensory Rehabilitation Strategies Post-TBI
Status: ENROLLING_BY_INVITATION
Conditions: Brain Concussion|Vestibular Disorder|Cognition Disorder|Mild Traumatic Brain Injury
Interventions: DEVICE: Praxis|BEHAVIORAL: Supervised cardiovascular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Early Postoperative Oral Carbohydrate on Postoperative Recovery of the Unilateral Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Postoperative Oral Carbohydrates|Postoperative Recovery|Unilateral Knee Arthroplasty
Interventions: OTHER: Early drinking water|COMBINATION_PRODUCT: Early consumption of carbohydrates|OTHER: Late feeding group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MCS110 With BRAF/MEK Inhibition in Patients With Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: MCS110|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: London Underground Study - Health Effects of Particulate Matter
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Exposure to London Underground ambient particulate matter|OTHER: Exposure to London air ambient particulate matter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Screening Plasma HER2 Amplication by Digital PCR in Advanced Breast Cancer Patients Treated With Trastuzumab and Pyrotinib
Status: UNKNOWN
Conditions: Advanced Breast Cancer
Interventions: DRUG: Trastuzumab and Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Glucagon Stimulation Test for Evaluation of Adult Growth Hormone Deficiency and Adrenocorticotropic Axis
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency|Hypothalamic-pituitary Disorders
Interventions: PROCEDURE: Glucagon stimulation test and insulin tolerance test|PROCEDURE: glucagon stimulation test and insulin tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Clinical Study of ZPR Regimen in Elderly Treatment-naive Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Zanubrutinib, Polatuzumab Vedotin, Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC
Status: COMPLETED
Conditions: MDS|Immunodeficiency|GATA2
Interventions: DRUG: Cyclophosphamide (CTX, Cytoxan)|DRUG: Fludarabine(Fludara,Berlex Laboratories)|PROCEDURE: Total Body Irradiation (TBI)|PROCEDURE: Allogeneic Hematopoietic Stem Cell (HSC)|DRUG: Equine Anti-Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bifidobacteria in Children Affected by Seasonal Allergic Rhinitis
Status: UNKNOWN
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Bifidobacteria|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ZD 1839 Plus Combination Chemotherapy in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: gefitinib|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Pulmonary Rehabilitation Outcomes in Patients With Chronic Respiratory Disease Based on Metabolomics: a Prospective Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Bronchiectasis
Interventions: OTHER: metabonomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GLucobay M - Evaluation Of Safety and Effectiveness in Type 2 Diabetes Not Well Controlled on Monotherapy in Real Life Practice
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Acarbose/Metformin (Glucobay M, BAY81-9783)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous Paracetamol, Dexketoprofen and Ibuprofen in the Treatment of Acute Migraine Attack Headache
Status: UNKNOWN
Conditions: Headache, Migraine
Interventions: DRUG: Paracetamol|DRUG: Dexketoprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Articulatory Gestures on Early Literacy Skills in 4-year Olds
Status: NOT_YET_RECRUITING
Conditions: Early Literacy|Articulatory Gestures|Phonemic Awareness
Interventions: BEHAVIORAL: phonemic segmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Alternative Injection Paradigm for OnabotulinumtoxinA (BOTOX®) in the Treatment of Overactive Bladder in Patients With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Urinary Incontinence
Interventions: BIOLOGICAL: onabotulinumtoxinA|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Auricular Acupuncture in Treating Insomnia Post-stroke
Status: RECRUITING
Conditions: Insomnia, Secondary|Post-stroke Depression
Interventions: OTHER: Auricular Acupuncture needles|OTHER: Sham Auricular Acupuncture needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: BDP/FF/GB|DRUG: Tiotropium|DRUG: BDP/FF + Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions
Status: RECRUITING
Conditions: Oral Potentially Malignant Lesions
Interventions: DRUG: Magnetite ZnO Composite Nanoparticles|DRUG: Topical Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Different Myofascial Release Techniques for the Pectoralis Minor Muscle
Status: RECRUITING
Conditions: Pectoralis Minor Muscle Tension|Muscle Shortness|Mobility Limitation|Forward Scapular Posture|Rounded Shoulder Posture
Interventions: OTHER: Self Myofascial Release|OTHER: Myofascial Release|OTHER: Instrument Assisted Soft Tissue Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Chinese Tradional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty
Status: NOT_YET_RECRUITING
Conditions: Precocious Puberty|Treatment|Alternative Medicine|Acupuncture
Interventions: OTHER: intradermal needles|DRUG: Ziyinxiehuo Granules of tradional Chinese Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy With REGN2810 and/or Ipilimumab Before Surgery in Treating Participants With Progressive Advanced or Oligometastatic Prostate Cancer
Status: WITHDRAWN
Conditions: Stage III Prostate Cancer|Stage IIIA Prostate Cancer|Stage IIIB Prostate Cancer|Stage IIIC Prostate Cancer|Stage IV Prostate Cancer|Stage IVA Prostate Cancer|Stage IVB Prostate Cancer
Interventions: BIOLOGICAL: Ipilimumab|RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Radical Prostatectomy|BIOLOGICAL: Anti-PD-1 Monoclonal Antibody REGN2810
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoral Cryotherapy on Cytokine Levels and Postoperative Endodontic Pain
Status: COMPLETED
Conditions: Apical Periodontitis
Interventions: DEVICE: Cryotherapy group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Correlation Between the n-6:n-3 Ratio and Inflammatory Markers in Small for Gestational Age (SGA) Infants Compared With Appropriate for Gestational Age (AGA) Infants
Status: UNKNOWN
Conditions: Small for Gestational Age Infants|Appropriate for Gestational Age Infants
Interventions: PROCEDURE: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of FMS Functional Movement Training on Body Posture Control in College Female Aerobics Athletes
Status: RECRUITING
Conditions: Postural Balance
Interventions: BEHAVIORAL: Functional Movement Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
Status: COMPLETED
Conditions: Muscle Weakness|Late Effect of Burn|Muscle; Fatigue, Heart|Burn Rehabilitation
Interventions: OTHER: Exercise + SOC PT/OT|OTHER: SOC PT/OT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques
Status: ACTIVE_NOT_RECRUITING
Conditions: Diseases of Liver|Colon Carcinoma|Colorectal Carcinoma|Liver Metastases
Interventions: DIAGNOSTIC_TEST: Computed Tomography Scan - 50% Dose Reduction|DIAGNOSTIC_TEST: Computed Tomography Scan - 70% Dose Reduction|DIAGNOSTIC_TEST: Deep Learning Image Reconstruction (DLIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Triple Negative Breast Cancer|Hodgkin Lymphoma|Head and Neck Squamous Cell Carcinoma|Malignant Melanoma
Interventions: DRUG: CTX-8371
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT