pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pre vs Post Block in Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthroplasty Complications|Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Acetaminophen|DRUG: Lyrica|DRUG: Celebrex|DRUG: Meloxicam|DRUG: Oxycodone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of High Intensity Circuit Training in Nature Vs. Indoor on Exercise Performance, and Wellbeing
Status: COMPLETED
Conditions: Green Exercise|Indoor Exercise
Interventions: BEHAVIORAL: High Intensity Circuit Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fasted Condition Versus as a Tablet After Food (Part 2)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Interventions: DRUG: SAR443820|DRUG: SAR443820
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine in Implant Based Breast Reconstruction
Status: TERMINATED
Conditions: Breast Cancer|Postoperative Pain
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine with epinephrine|DRUG: Morphine sulfate|DRUG: Hydrocodone/acetaminophen|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Postoperative Cognitive Dysfunction After Closed Loop Anesthesia vs Inhalational Anesthesia or TIVA
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction
Interventions: DEVICE: auto total endovenous anesthesia|DEVICE: Manual Desflurane anesthesia|DEVICE: Manual Sevoflurane anesthesia|DEVICE: Manual total endovenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Effects of Acute Red Raspberry Consumption on Vascular Function in Healthy Individuals
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 400 g frozen raspberries|DIETARY_SUPPLEMENT: 200 g frozen raspberries|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study to Evaluate Right Ventricular Function With Riociguat in CTEPH
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: RADIATION: Cardiac PET imaging using F-18-FDG, N-13 ammonia( NH3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Inhaled Cannabis in Diabetic Painful Peripheral Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study
Status: RECRUITING
Conditions: Psychotic Disorders|Family Members|Anosognosia|Paranoia
Interventions: BEHAVIORAL: Supporting Patients by Family Education in Psychotic Illness Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Intact Umbilical Cord Milking on Neonatal and First Year Neurodevelopmental Outcomes in Very Preterm Infants.
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant|Umbilical Cord Milking
Interventions: PROCEDURE: Intact Umbilical Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine.
Status: COMPLETED
Conditions: Renal Colic
Interventions: DRUG: Magnesium sulfate and diclofenac|DRUG: Lidocain and diclofenac|DRUG: Placebo and diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Gut Health
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: High quantity probiotic|OTHER: Low quantity probiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Using Solum IV and BMC With GFC in TLIF
Status: WITHDRAWN
Conditions: Degenerative Disc Disease|Isthmic-lytic Spondylolisthesis|Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: COMBINATION_PRODUCT: Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Celecoxib Versus Diclofenac In Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Celecoxib 200 milligrams|DRUG: Celecoxib 400 milligrams|DRUG: diclofenac 50 milligrams
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thulium Fiber Laser (TFL) vs Holmium MOSES for Treatment of Benign Prostatic Hyperplasia (BPH)
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Thulium Fibre Laser|DEVICE: MOSES Holmium Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Ceftriaxone and Oral Doxycycline for Lyme Neuroborreliosis
Status: COMPLETED
Conditions: Lyme Neuroborreliosis
Interventions: DRUG: Ceftriaxone|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extracorporeal Shockwave Versus Phonophoresis Using Chitosan-Nanoparticles Gel on Functional and Anatomical Changes Detected With Artificial Intelligence Based Texture Analysis Algorithm in Knee Osteoarthritis Patients: A Double Blind Randomized Controlled Trial
Status: RECRUITING
Conditions: Knee Osteoarthritis|Chitosan Nanoparticles Gel|Artificial Intelligence Texture Analysis Bases Algorithm|Subchondral Bone Changes (Anatomical Changes)|Extracorporeal Shockwave
Interventions: COMBINATION_PRODUCT: Ultrasound therapy combined with Chitosan nanoparticles gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hypercapnic Respiratory Failure|Chronic Obstructive Pulmonary Disease|Obesity Hypoventilation Syndrome (OHS)|Nasal High Flow|Health-related Quality of Life
Interventions: DEVICE: Nasal High Flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Effectiveness of Epiduo® Gel in Reducing Antibiotic Sensitive & Resistant Strains of Propionibacterium (P)Acnes
Status: COMPLETED
Conditions: P Acnes Colonization
Interventions: DRUG: Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel (Epiduo® Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Long-Term Study Examining the Treatment of Benign Prostatic Hyperplasia With Photoselective Vaporization
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: GreenLight HPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 400 μg Twice Daily of Aclidinium Bromide vs. Placebo When Administered to Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: aclidinium bromide 400 μg|DRUG: aclidinium bromide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study to Assess an Automated Laser Device for Direct Selective Laser Trabeculoplasty
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DEVICE: Direct Selective Trabeculoplasty|DEVICE: Selective Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oblique Subcostal Transversus Abdominis Plane Block Versus Transmuscular Quadratus Lumborum Block for Pain Management in Laparoscopic Gynecological Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Surgery
Interventions: PROCEDURE: Oblique Subcostal Transversus Abdominis Plane Block|PROCEDURE: Transmuscular Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Study of a Histone Deacetylase (HDAC) Inhibitor Plus Targretin in Cutaneous T-Cell Lymphoma Patients (0683-016)(TERMINATED)
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: vorinostat|DRUG: Comparator: bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Retention After Arthroplasty
Status: RECRUITING
Conditions: Urinary Retention Postoperative|Arthroplasty Complications
Interventions: OTHER: Catheterization based on ultrasound|OTHER: Catheterization based on evaluation of symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindfulness-based Illness Management Program for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Routine Care|BEHAVIORAL: Mindfulness-based program|BEHAVIORAL: Psychoeducation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study to Evaluate the Effect of Treatment With Romosozumab or Teriparatide in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Romozosumab|DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin/Metronidazole Based Quadruple Therapy for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Dyspepsia|Peptic Ulcer
Interventions: DRUG: Lansoprazole|DRUG: Bismuth Potassium Citrate|DRUG: Amoxicillin|DRUG: Metronidazole|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Oxygen During CPET in GUCH
Status: COMPLETED
Conditions: Grown-up Congenital Heart Disease (GUCH)
Interventions: PROCEDURE: Oxygen application|PROCEDURE: Sham room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internal Hernia After Laparoscopic Gastric Bypass
Status: COMPLETED
Conditions: The Prevalence of Surgery for Small Bowel Obstruction After LGBP Procedure.
Interventions: PROCEDURE: Suturing of mesenteric defects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CORolla® TAA for Heart Failure With Preserved Ejection Fraction (HFpEF) and Diastolic Dysfunction (DD)
Status: UNKNOWN
Conditions: Diastolic Heart Failure|Diastolic Dysfunction
Interventions: DEVICE: CORolla™ TAA device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults
Status: COMPLETED
Conditions: Mental Health|Geriatrics
Interventions: DRUG: donepezil|DRUG: Placebo (cornstarch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Premedication for Non-Emergency Endotracheal Intubation In the NICU
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Rocuronium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Remimazolam Tosilate in Patients Undergoing Bronchoscopy
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Remimazolam Tosilate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Peri-Operative And Long-Term Cardioprotective Properties Of Sevoflurane In High Risk Patients Undergoing Non-Cardiac Surgery
Status: COMPLETED
Conditions: Non Cardiac Surgery
Interventions: DRUG: Sevoflurane or Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: nusinersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: LOU064 (blinded)|DRUG: Placebo|DRUG: LOU064 (open label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Biofeedback Tool to Minimize Procedural Pain and Anxiety in Children
Status: UNKNOWN
Conditions: Pain|Anxiety
Interventions: DEVICE: Belly breathing with biofeedback app|BEHAVIORAL: Belly breathing without biofeedback app|BEHAVIORAL: Belly breathing + visual distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Self-sampling and Human Papillomavirus (HPV)-Testing for Unscreened Women in Cervical Cancer Prevention
Status: COMPLETED
Conditions: Cervical Cancer|Human Papillomavirus Infection
Interventions: BEHAVIORAL: Attending for cervical cytology|BEHAVIORAL: Kit for Self-collected vaginal sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Treatment Exercises With Core Stability and Dynamic Resistance Exercise for Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: OTHER: Alendronate|OTHER: treatment exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated With Mitomycin C Following Femtosecond Flap Creation.
Status: TERMINATED
Conditions: Presbyopia
Interventions: DRUG: Mitomycin c|DEVICE: Raindrop Near Vision Inlay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Low Dose Chemotherapy Plus Sorafenib as Initial Therapy for Patients With Advanced Non-Squamous Cell NSCLC
Status: TERMINATED
Conditions: Non Squamous Cell Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: Docetaxel + Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustaining Aviator Performance During Extended Operational Flight
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Active Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Risperidone Tablet 1 mg Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Risperidone Tablet 1 mg|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Therapy in Patients With Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Arthritis, Rheumatoid|Periodontitis
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HORIZON CE Pivotal Study to Treat Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Infrarenal Abdominal Aortic Aneurysms|Aortoiliac Aneurysms
Interventions: DEVICE: Horizon™ Abdominal Aortic Aneurysm Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study for Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings and Its Impact on Adolescent Mental and Behavioral Health
Status: COMPLETED
Conditions: Depression Anxiety and Co-occurring Rural Youth
Interventions: OTHER: internet based iCBT program, Youth Thrive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Regimens MPIB, CIPCEA, PCEA
Status: ACTIVE_NOT_RECRUITING
Conditions: Breakthrough Pain
Interventions: DEVICE: epidural delivery system|DRUG: Ropivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
Status: UNKNOWN
Conditions: ADHD|Child, Only
Interventions: BEHAVIORAL: Family based Executive Function Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testosterone Plus Finasteride Treatment After Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injury|Spinal Cord Injuries|Trauma, Nervous System|Wounds and Injuries|Central Nervous System Diseases|Nervous System Diseases|Spinal Cord Diseases|Gonadal Disorders|Endocrine System Diseases|Hypogonadism|Genital Diseases, Male
Interventions: DRUG: Testosterone Enanthate|DRUG: Finasteride|DRUG: Placebo injection|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Naltrexone in the Treatment of Dissociative Symptoms in Patients With Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder|Dissociation
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Status: NOT_YET_RECRUITING
Conditions: Cervical Spinal Cord Injury
Interventions: DEVICE: Epidural Spinal Cord Stimulation (eSCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaporous Hyperoxia Therapy (VHT) in the Treatment of Foot Wounds
Status: COMPLETED
Conditions: Neuropathic Foot Ulcer|Foot Ulcer
Interventions: DEVICE: Vaporous Hyperoxia Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: FG-3019|DRUG: FG-3019
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety and Interchangeability of Two Tbe Vaccines Administered According to a Conventional Schedule in Children
Status: COMPLETED
Conditions: Encephalitis, Tick-Borne
Interventions: BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)|BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ventilation Knowledge and Skills Retention Using a Novel Tool, the Augmented Infant Resuscitator (AIR) Device as an Instant-feedback Tool
Status: UNKNOWN
Conditions: Ventilation Skills Acquisition and Retention|Ventilation Knowledge Acquisition and Retention
Interventions: OTHER: Simulation enhanced HBB training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Polyherbal Capsule Formulation for Joint Health
Status: COMPLETED
Conditions: Knee Discomfort|Pain Physical Activity
Interventions: DIETARY_SUPPLEMENT: Polyherbal capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Vandetanib|DRUG: Vandetanib|DRUG: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Drug-drug Interaction of BMS 663068 With Methadone and Also With Buprenorphine/Naloxone
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068|DRUG: Methadone|DRUG: Buprenorphine and Norbuprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Influence of Antenatal Classes on Pregnancy, Birth and Parenthood
Status: COMPLETED
Conditions: Pregnancy|Parturition
Interventions: OTHER: Antenatal classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v7|Metastatic Malignant Neoplasm in the Bone
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Functional Brain Network in Altered Meditation State With Multimodal Neuroimaging
Status: UNKNOWN
Conditions: Meditation|Mindfulness
Interventions: DEVICE: external meditation guided audio|DEVICE: internal meditation guided audio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
Status: RECRUITING
Conditions: Behcet Disease|Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis|Takayasu Arteritis|Giant Cell Arteritis|Sjogren's Syndrome|Rheumatoid Arthritis|Hereditary and Acquired Angioedema|Primary Antiphospholipid Syndrome|Celiac Disease
Interventions: OTHER: Usual medical management of patients, additional blood and stool samples for biobanking
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Support for Women at Risk for Heart Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Coronary Disease|Coronary Heart Disease Risk Reduction|Diabetes Mellitus, Non-insulin Dependent
Interventions: BEHAVIORAL: diet|BEHAVIORAL: physical activity|BEHAVIORAL: stress management|BEHAVIORAL: smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of a Fixed Dose Combination Tablet Containing 400 mg Ibuprofen and 60 mg Pseudoephedrine-HCl Compared to Two Film Coated Fixed Dose Combination Tablets RhinAdvil(R)(200 mg Ibuprofen and 30 mg Pseudoephedrine-HCl) Administered in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ibuprofen|DRUG: Pseudoephedrine-HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Cooling Agent Pilot Among Adult Menthol Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Dependence
Interventions: OTHER: Assigning cooling agent type cigarettes|OTHER: Assigning traditional tobacco type cigarettes|OTHER: Assigning menthol type cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: sNN0029|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of PTNS and Biofeedback for Fecal Incontinence
Status: WITHDRAWN
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Posterior tibial nerve stimulation|PROCEDURE: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resources to Enhance the Adjustment of Children (REACH)
Status: COMPLETED
Conditions: Oppositional Defiant Disorder|Conduct Disorder|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Booster Treatment|BEHAVIORAL: No-Booster|OTHER: No intervention|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthesia for Facial Fractures
Status: RECRUITING
Conditions: Pain Management
Interventions: DRUG: Bupivacaine/Epinephrine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature|Intracranial Hemorrhages|Leukomalacia, Periventricular|Cerebral Palsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Investigating the Effect of Patient Pelvic Positioning and Method of Acetabular Component Insertion on Acetabular Component Inclination During Total Hip Arthroplasty (THA)
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Total Hip Replacement|THA|THR
Interventions: PROCEDURE: Operating table position 0° head down (Horizontal)|PROCEDURE: Operating table position 7° head down.|PROCEDURE: Operating table position Y° head down|DEVICE: Standard straight acetabular component introducer without alignment guide.|DEVICE: Modified 35° acetabular component introducer.|DEVICE: Inclinometer-assisted acetabular component introducer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Synaptic Plasticity and Cognitive Function in RASopathies
Status: TERMINATED
Conditions: Impaired Synaptic Plasticity|Impaired Cognition
Interventions: DRUG: Lovastatin|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image Fusion System for 3D Preoperative Planning in the Osteosynthesis and Osteotomy
Status: RECRUITING
Conditions: Fractures, Bone|Fracture Malunion, Bone
Interventions: DEVICE: Image fusion system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gut to Brain Interaction in Autism. Role of Probiotics on Clinical, Biochemical and Neurophysiological Parameters
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DIETARY_SUPPLEMENT: Vivomixx®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Metabolic and Haemodynamic Effects of Metformin and Glimepiride in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Lasilactone|OTHER: Sodium-Restricted Diet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker-Integrated Approach of Targeted Therapy for Lung Cancer Elimination Plus External Beam Radiation Therapy (BATTLE-XRT)
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: Onartuzumab|DRUG: Erlotinib|DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Chemotherapy Effect|Immune Checkpoint Inhibitor
Interventions: DRUG: Sintilimab, paclitaxel-albumin, oxaliplatin, 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Prostate Biopsy - Micro-Ultrasound Versus MRI
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Micro-US Targeted Biopsy|DIAGNOSTIC_TEST: MRI Targeted Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DRUG: Alpha Lipoic Acid 600 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth
Status: COMPLETED
Conditions: SARS-CoV 2|SARS Pneumonia
Interventions: BEHAVIORAL: Therapy Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety From a High-dosed Sublingual Grass Pollen Preparation
Status: COMPLETED
Conditions: Allergy|Rhinitis|Conjunctivitis
Interventions: BIOLOGICAL: Allerslit forte|BIOLOGICAL: Allerslit forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Target the Type I IFN Receptor by Administrating Anifrolumab in RA Patients With a High IFN Signature (TarIFNiRA)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Anifrolumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Hemodynamic Optimization Using the Photoplethysmography in Colorectal Surgery
Status: COMPLETED
Conditions: Polyp of Large Intestine|Colorectal Neoplasms|Crohn Disease
Interventions: DEVICE: Photoplethysmography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Safety Study in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic
Interventions: DRUG: SGN-40 (anti-huCD40 mAb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ripple Mapping Guided Ablation of Ischaemic Ventricular Tachycardia.
Status: COMPLETED
Conditions: Ventricular Tachycardia|Ischemic Heart Disease
Interventions: PROCEDURE: Ripple Mapping guided ischaemic VT ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omalizumab to Accelerate a Symptom-driven Multi-food OIT
Status: RECRUITING
Conditions: Food IgE-mediated Allergy|Immunotherapy|Omalizumab|Physiological Effects of Drugs
Interventions: BIOLOGICAL: Omalizumab 16mg/kg|BIOLOGICAL: Omalizumab 8mg/kg|BIOLOGICAL: Placebo|OTHER: Multi-food oral immunotherapy (OIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Cycle Control With Norgestimate/Ethinyl Estradiol and Drospirenone/Ethinyl Estradiol in Healthy Sexually Active Females
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Norgestimate/ethinyl estradiol; Drospirenone/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB104 in Healthy Japanese and Non-Japanese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BIIB104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PICC-ports Versus Chest - Ports for Long Term Chemotherapy Deliverance in Oncology Patients
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DEVICE: PICC-port|DEVICE: Chest-port
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mirror Therapy Integrated With Electrical Stimulation for Cortical Modulations
Status: RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: BEHAVIORAL: Mirror therapy|DEVICE: Neuromuscular electrical stimulation|BEHAVIORAL: Motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study About How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated in Healthy Japanese Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1358894|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache
Status: COMPLETED
Conditions: Migraine With Aura|Migraine Without Aura
Interventions: DRUG: Dronabinol MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hizikia Fusiformis Extract in Subjects Showing Erosive Gastritis
Status: COMPLETED
Conditions: Erosive Gastritis
Interventions: DIETARY_SUPPLEMENT: Hizikia Fusiformis extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Docetaxel in Treating Patients With Solid Tumors and Abnormal Liver Function
Status: COMPLETED
Conditions: Breast Cancer|Head and Neck Cancer|Lung Cancer|Ovarian Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Forms of Tafamidis Without Food and the Amount of Tafamidis in the Blood With Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tafamidis free acid tablet (Test)|DRUG: Tafamidis meglumine capsule (Reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Umbilical Cord Care for the Prevention of Colonization and Invasive Infections
Status: COMPLETED
Conditions: Colonization
Interventions: DRUG: Povidone-Iodine|DRUG: Chlorhexidine|DRUG: Pluronic|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dentin Treatments for Restorations of Cervical Lesions Non-Carious
Status: UNKNOWN
Conditions: Adhesion
Interventions: PROCEDURE: Treatment of Dentin Surface|PROCEDURE: Dentin Surface|PROCEDURE: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on the Contribution of Guided Puncture With Echoendoscopy
Status: COMPLETED
Conditions: Hypermetabolic Lymphadenopathy Mediastinum Lower, Posterior and Middle, Detected by PET-CT With 18F-FDG (PET)
Interventions: PROCEDURE: Guided punction of mediastinal lymphadenopathy by echoendoscopy|DEVICE: PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intracardiac Flow Assessment in Cardiac Amyloidosis
Status: RECRUITING
Conditions: Amyloidosis Cardiac|Healthy Adults
Interventions: DIAGNOSTIC_TEST: Cardiac magnetic resonance image (CMR)|DIAGNOSTIC_TEST: Transthoracic Echocardiogram (TTE)|DIAGNOSTIC_TEST: Six-minute Walk Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Durvalumab (Anti-PDL1) Plus Radiation Therapy for the Treatment of Solitary Bone Plasmacytoma
Status: WITHDRAWN
Conditions: Solitary Bone Plasmacytoma
Interventions: DRUG: Durvalumab|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study for Endostar Continuous Intravenous Infusion in NSCLC Patients With 1st-line Platinum Based Chemotherapy
Status: UNKNOWN
Conditions: Advanced or Metastatic NSCLC
Interventions: DRUG: Endostar|DEVICE: use the vein pump to pump drugs|COMBINATION_PRODUCT: combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimal dRug Eluting steNts Implantation Guided By Intravascular Ultrasound and Optical coheRence tomoGraphy ORENBURG
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Disease|Heart Diseases
Interventions: PROCEDURE: IVUS-guided group|PROCEDURE: Non-IVUS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblings
Status: COMPLETED
Conditions: Acute Leukemia|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: vaccine COMIRNATY® (BNT162b2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High-Intensity Interval Training for Women at Heightened Risk for Breast Cancer
Status: COMPLETED
Conditions: Disorders of Breast
Interventions: OTHER: Exercise|BEHAVIORAL: Questionnaires|BEHAVIORAL: Motivational Session|BEHAVIORAL: Phone Call|OTHER: Printed Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Type II Diabetes
Interventions: DRUG: GLP-1 agonists|PROCEDURE: Cardiac MRI|OTHER: Follow up by phone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of Transcranial Laser Therapy Within 24 Hours From Stroke Onset (NEST-3)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: NeuroThera® Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture to Assist Ventilator Weaning in Severe Stroke
Status: RECRUITING
Conditions: Severe Stroke|Electroacupuncture
Interventions: OTHER: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Hypothermia Improves Outcome of Hypoxic-Ischemic Encephalopathy
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: DEVICE: hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia
Status: COMPLETED
Conditions: Phobic Disorders|Anxiety|Social Phobia
Interventions: DRUG: D-Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of McGrath and Macintosh Laryngoscope for DLT Intubation
Status: COMPLETED
Conditions: Intubation; Difficult|Thoracic Diseases|Intubation Complication
Interventions: DEVICE: videolaryngoscope|DEVICE: Direct laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxycycline for Lateral Epicondylalgia - RCT
Status: UNKNOWN
Conditions: Lateral Epicondylalgia (Tennis Elbow)
Interventions: DRUG: Placebo|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-guided RadioFrequency Ablation for the Treatment Pancreatic NeuroEndocrine Neoplasms
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Neuroendocrine Carcinoma|Pancreas Neoplasm|Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting
Interventions: DEVICE: EUS guided radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation
Status: RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
Status: RECRUITING
Conditions: ACL Injury
Interventions: OTHER: Blood Flow Restriction (BFR) therapy|OTHER: Standard REHAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Mild Intermittent Hypoxia|OTHER: Sham MIH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT