pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants
Status: COMPLETED
Conditions: Poliomyelitis|Diphtheria|Haemophilus Influenzae Type b|Tetanus|Acellular Pertussis|Hepatitis B
Interventions: BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Pediarix|BIOLOGICAL: ActHIB|BIOLOGICAL: Pentacel|BIOLOGICAL: Engerix-B|BIOLOGICAL: Infanrix|BIOLOGICAL: Hiberix|BIOLOGICAL: Prevnar13|BIOLOGICAL: Rotarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of GSK Biologicals' Combined Measles-mumps-rubella Vaccine in Volunteers, Seven Years of Age and Older
Status: COMPLETED
Conditions: Rubella|Mumps|Measles
Interventions: BIOLOGICAL: Priorix®|BIOLOGICAL: Merck's M-M-R®II, Measles, Mumps, and Rubella Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Two Vaccine Strategies in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: BIOLOGICAL: Prevenar® and Pneumo23®|BIOLOGICAL: Placebo, Pneumo23®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Outcomes of Treatment-Resistant Depression in Older Adults
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder|Treatment-Refractory Depression|Late Life Depression|Geriatric Depression
Interventions: DRUG: Aripiprazole Augmentation|DRUG: Bupropion Augmentation|DRUG: Switch to bupropion|DRUG: Lithium Augmentation|DRUG: Switch to nortriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Choice of Palliative Procedures for Pulmonary Atresia With Ventricular Septal Defect Patients
Status: COMPLETED
Conditions: Pulmonary Atresia With Ventricular Septal Defect|Tetralogy of Fallot With Pulmonary Atresia
Interventions: PROCEDURE: Experimental: RVOT reconstruction by femoral allogenic vein valve conduit|PROCEDURE: Systemic-to-pulmonary artery shunts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)
Status: COMPLETED
Conditions: Infections|Community Acquired Pneumonia
Interventions: DRUG: Ceftaroline fosamil|DRUG: Ceftriaxone|DRUG: amoxicillin clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laser En Bloc Resection Of Bladder Tumor (HoLERBT) VS. Conventional Transurethral Resection Of Bladder Tumors (cTURBT)
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: HoLERBT|DEVICE: cTURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Camrelizumab Plus Radiotherapy for Patients With Early Triple-Negative Breast
Status: RECRUITING
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Camrelizumab|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Kinase Inhibitor
Status: ACTIVE_NOT_RECRUITING
Conditions: Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Interventions: DRUG: Asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Footwear on Balance and Confidence in Older Inpatients
Status: UNKNOWN
Conditions: Postural Balance|Accidental Falls
Interventions: OTHER: Outdoor Shoes|OTHER: Pillow Paw Slippers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Central Effects of Botulinum Toxin: Neurophysiological Study in Stroke Patients With Spastic Lower Limb
Status: UNKNOWN
Conditions: Hemiplegic Patients Post-AVC
Interventions: DRUG: injection botox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A4i-O: A Platform for Complex Behavioral Health to Address OUD
Status: RECRUITING
Conditions: Opioid-Related Disorders|Relationship, Professional Patient|Mental Health Wellness 1|Mobile Phone Use|Comorbidities and Coexisting Conditions
Interventions: DEVICE: App for Independence-O (A4i-O)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effects of the CDSMP Among Lower-to-Middle Wage Workers
Status: COMPLETED
Conditions: Chronic Disease
Interventions: BEHAVIORAL: Chronic Disease Self-Management Program (CDSMP)|BEHAVIORAL: Financial Self-Management Program (FSMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Solid Neoplasm|Pancreatic Acinar Cell Carcinoma|Pancreatic Ductal Adenocarcinoma|Recurrent Pancreatic Carcinoma|Stage IV Pancreatic Cancer AJCC v6 and v7
Interventions: OTHER: Diagnostic Laboratory Biomarker Analysis|DRUG: Erlotinib Hydrochloride|DRUG: Gemcitabine Hydrochloride|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarcosine Preventive Therapy for Individuals At High Risk for Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenias|Psychoses|Psychotic Disorders|Schizophrenic Disorders
Interventions: DRUG: Sarcosine (N-methylglycine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Healthy Adults 50 Years of Age or Older (V114-016/PNEU-PATH)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: Prevnar 13™|BIOLOGICAL: PNEUMOVAX™23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Can Additional Preoperative Skin Cleaning on Face, Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?
Status: UNKNOWN
Conditions: C. Acnes|Arthroscopic Rotator Cuff Repair
Interventions: DRUG: 2% chlorhexidine gluconate skin cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Specimen Imaging Using High-resolution 18F-FDG-PET-CT During Thoracic Surgery: a Pilot Study
Status: RECRUITING
Conditions: Lung Neoplasms|PET-CT Specimen Imager
Interventions: DEVICE: AURA10 Specimen Imager
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MRI-guided Transurethral Urethral Ultrasound Ablation for the Treatment of Intermediate Grade Prostate Cancer
Status: RECRUITING
Conditions: Prostate Carcinoma|Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8
Interventions: PROCEDURE: MRI-Guided Transurethral Ultrasound Ablation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Digital Rectal Examination|PROCEDURE: Cystoscopy|PROCEDURE: Biopsy|PROCEDURE: Bone Scan|PROCEDURE: PSMA PET Scan|PROCEDURE: Multiparametric Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: US Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation
Status: COMPLETED
Conditions: Analgesia|Breast Cancer
Interventions: PROCEDURE: Erector Spinae Plane Block with Bubivacaine|PROCEDURE: Standard General Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Concurrent Chemoradiotherapy in Treating Patients With High-Risk Salivary Gland Carcinomas
Status: COMPLETED
Conditions: Salivary Gland Tumors|Head and Neck Cancer
Interventions: DRUG: Nedaplatin|DRUG: Docetaxel|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib Combined With Fluorouracil and Leucovorin in Treating Patients With Resected Stage III Adenocarcinoma (Cancer) of the Colon
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: celecoxib|DRUG: fluorouracil|DRUG: leucovorin calcium|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Single-Port Versus Multi-Port Robotic Radical Prostatectomy
Status: SUSPENDED
Conditions: Malignant Neoplasm of Prostate
Interventions: DEVICE: Da Vinci ® Xi system - MP Robotic Radical Prostatectomy|DEVICE: Da Vinci ® SP system - SP Robotic Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Portal Vein Flow Variability to Quantify Right-Sided Hemodynamic Congestion (PORTAL)
Status: RECRUITING
Conditions: Congestion|Heart Failure|Right Heart Catheterisation|Central Venous Pressure|Doppler Echocardiography
Interventions: DIAGNOSTIC_TEST: Comprehensive transthoracic echocardiography, Doppler echography & Kino-cardiograph (Kino)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Spinal or Sevoflurane Anesthesia on Neutrophil Activation During Knee Surgery With Pneumatic Tourniquet
Status: COMPLETED
Conditions: Knee Surgery With Tourniquet
Interventions: DRUG: Sevoflurane Volatile Liquid|DRUG: Bupivacaine / SUFentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A First Time in Human Study of SNP318 as a Treatment for Neurodegenerative Diseases Including Alzheimer's Disease
Status: COMPLETED
Conditions: Neurodegenerative Diseases|Alzheimer's Disease
Interventions: DRUG: SNP318 (A)|DRUG: Placebo (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Artery Infusion of Adebrelimab Combined With Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma With Failure of Systemic Therapy Combined With Interventional Therapy
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: HAIC|DRUG: Adebrelimab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Normal saline|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Renal Protection Of Dexmedetomidine Versus Midazolam As a Sedative For Septic Patients In Intensive Care Unit
Status: RECRUITING
Conditions: Renal Failure
Interventions: DRUG: Midazolam|DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Mastery of Inhaler Technique for Budesonide Formoterol (BF) SPIROMAX® as Compared to SYMBICORT® TURBOHALER® as Treatment for Adult Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide and formoterol fumarate dehydrate (BF) SPIROMAX|DRUG: SYMBICORT TURBOHALER budesonide and formoterol fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer
Status: SUSPENDED
Conditions: Prostate Adenocarcinoma|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: PROCEDURE: MRI-guided Intensity-Modulated Radiation Therapy|DRUG: Antiandrogen Therapy|PROCEDURE: PSMA PET Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Bone Scan|PROCEDURE: Biospecimen Collection|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Oral Cdk Inhibitor Administered With an Oral BRAF Inhibitor in Patients With Advanced or Inoperable Malignant Melanoma With BRAF Mutation
Status: SUSPENDED
Conditions: Advanced or Inoperable Malignant Melanoma With BRAF Mutation
Interventions: DRUG: P1446A-05|DRUG: Vemurafenib (Zelboraf®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas
Status: WITHDRAWN
Conditions: Central Nervous System Tumors
Interventions: DRUG: Bevacizumab, CA4P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of L-arginine to Mitigate the Cardiovascular Effects of Exposure to Traffic-related Air Pollution
Status: COMPLETED
Conditions: Blood Pressure|Cardiac Ischemia
Interventions: DIETARY_SUPPLEMENT: L-Arg supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Direct Comparison of Spinal Cord Stimulator Parameter Settings
Status: COMPLETED
Conditions: Spinal Cord Stimulation|High-frequency Stimulation|High-density Stimulation
Interventions: DEVICE: High-frequency stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Milk Derived Peptides on Glycaemic Control
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Water Control|DIETARY_SUPPLEMENT: Milk derived hydrolysate|DIETARY_SUPPLEMENT: Parent Protein|OTHER: Lipid Load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compare Effectiveness of Eplerenone vs Atenolol in Reversing the Remodelling Resistance Arteries in Subjects With HT
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Herbal Tea in the Treatment of Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Herbal Tea|DRUG: Placebo Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® Gel 3% in the Treatment of Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Diclofenac Sodium Gel 3%|DRUG: Solaraze® (diclofenac sodium) Gel 3%|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lutein and Zeaxanthin Supplementation on Vision in Patients With Albinism
Status: COMPLETED
Conditions: Ocular Albinism (OA)|Oculocutaneous Albinism (OCA)
Interventions: DIETARY_SUPPLEMENT: Lutein plus Zeaxanthin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture|Acute Pain|Pain, Postoperative|Knee Injuries
Interventions: DRUG: Bupivacaine Injection|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recording Heart Rate Variability During Eye Movement Desensitisation Reprocessing With or Without Eye Movement
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Eye Movement Desensitisation Reprocessing|DEVICE: HeartMath measuring Heart Rate Variability (HRV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Between Single Administration of ASC-01 (Aripiprazole/Sertraline Combination Drug) and Concomitant Single Administration of Aripiprazole and Sertraline, and Food Effect on Pharmacokinetics of ASC-01 in Healthy Male Adults
Status: COMPLETED
Conditions: Healthy Male Adults
Interventions: DRUG: ASC-01|DRUG: Aripiprazole and sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Naps and Overnight Sleep on Cognitive Learning in Preschoolers
Status: UNKNOWN
Conditions: Sleep
Interventions: BEHAVIORAL: Nap/wake conditions on memory|BEHAVIORAL: Nap/wake conditions on overnight physiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prednisone Plus Tripterygium Wilfordii Treatment of Adult Patients With Idiopathic Focal Segmental Glomerulosclerosis
Status: COMPLETED
Conditions: Proteinuria|Focal Segmental Glomerulosclerosis
Interventions: DRUG: tripterygium wilfordii (TW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Genes and the Environment in Patients With Ovarian Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United Kingdom
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine in HER-2 Positive Breast Cancer With Pathologic Residual Tumors After Preoperative Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximizing Analgesia to Reduce Pain in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Blinded study medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Mesenchymal Stem Cells-derived Exosomes in Decompensated Liver Cirrhosis
Status: RECRUITING
Conditions: Decompensated Liver Cirrhosis
Interventions: BIOLOGICAL: MSC-derived exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Anlotinib on Pharmacokinetics to Assess the Effect of High Fat Diet in Advanced Cancer Patients
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Anlotinib|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Celecoxib Or Diclofenac For Efficacy and Safety In Chinese Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Celecoxib|DRUG: Diclofenac SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Atomoxetine To Enhance COgnition In Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors (TKIs) in Chronic Phase Chronic Myelogenous Leukemia Patients in CCR (ACTIW)
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Chronic-Phase
Interventions: DRUG: Pioglitazone|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Posaconazole Tablet in Participants at High Risk for Invasive Fungal Infections (MK-5592-065/P05615)
Status: COMPLETED
Conditions: Fungal Infections
Interventions: DRUG: Posaconazole 200 mg|DRUG: Posaconazole 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Clinical Application of Ultramicro-flow Technique in the Treatment of Benign Uterine Tumors With High-intensity Focused Ultrasound
Status: NOT_YET_RECRUITING
Conditions: Patients With Uterine Fibroids Receiving HIFUA Treatment ,and Can Undergo Regular Follow-up
Interventions: OTHER: Different methods of efficacy evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clobetasol Versus Pimecrolimus for Vulvar Lichen Sclerosus
Status: COMPLETED
Conditions: Lichen Sclerosus
Interventions: DRUG: pimecrolimus and clobetasol|DRUG: clobetasol 0.05% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP4345 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ASP4345|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Innovative Scheimpflug Topography Derived RGP Contact Lens Designs In Optometry Network
Status: COMPLETED
Conditions: Keratoconus
Interventions: DEVICE: The contact lens to be investigated in this study (Scheimpflug topography derived corneal RGP contact lens design). A CE (UKCA) marked class 2 medical devices.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Miofascial Release and Exercises Therapy in the Treatment of Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: myofascial release protocol and Rocabado exercise therapy|OTHER: exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of MOVI Interventions on Adiposity, Cognition and Motor Competence: MOVI-da10!
Status: COMPLETED
Conditions: Physical Activity|Children|Obesity|Cardiovascular|Cardiorespiratory Fitness
Interventions: BEHAVIORAL: MOVI-da10! active breaks|BEHAVIORAL: MOVI-da10! integrated physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Thiamine hydrochloride|DRUG: Riboflavin|DRUG: Ascorbic acid|DRUG: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: LIA of the posterior capsule of the knee|PROCEDURE: LIA of the anterior capsule of the knee|PROCEDURE: LIA of the subcutaneous tissue of the knee|PROCEDURE: FNB with catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Tolerability of Transcranial Direct Current Stimulation With Concurrent Cognitive Training
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Survivors
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Study of Leuprolide Vs Oral Contraceptive Therapy Vs Leuprolide and Oral Contraceptive Therapy for Ovarian Hyperandrogenism
Status: COMPLETED
Conditions: Hyperandrogenism
Interventions: DRUG: leuprolide|DRUG: Ethinyl estradiol/norethindrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subsequent Cisplatin and Docetaxel in Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: docetaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Cystic Fibrosis-related Diabetes|Cystic Fibrosis
Interventions: DEVICE: Access to Dexcom G7 CGM Data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain State-dependent PCMS in Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: Brain state-dependent paired corticomotoneuronal stimulation (PCMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thymoglobulin Induction in Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Kidney Transplantation|Ischemia-Reperfusion Injury
Interventions: DRUG: antithymocyte globulin|DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Alogliptin and With Pioglitazone in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin and Pioglitazone|DRUG: Alogliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Pharmacokinetic of Biosimilar Eptacog Alfa With Novoseven®, in Patients With Congenital Factor VII Deficiency
Status: COMPLETED
Conditions: Factor VII Deficiency
Interventions: BIOLOGICAL: Eptacog alfa, biosimilar|BIOLOGICAL: Novoseven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Aquaretic Tolvaptan on Nitric Oxide System (TORA)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Nephropathy
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuity of Care Between Primary Care Cardiology and Specialty Services for Patients With Chronic Ischemic Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Ischemic Heart Disease|Acute Coronary Syndrome
Interventions: DRUG: Inclisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimum Intervention to Maintain a Postpartum Depression Prevention Program in Clinics Serving Low-income Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Postpartum
Interventions: BEHAVIORAL: EIAU|BEHAVIORAL: LICF|BEHAVIORAL: HICF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Losartan in Pediatric Chronic Kidney Disease With Tubular Proteinuria
Status: COMPLETED
Conditions: Proteinuria
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours
Status: COMPLETED
Conditions: Solid Tumors|Central Nervous System Tumors
Interventions: DRUG: Vinblastine and Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramelteon in Chinese Patients With Chronic Insomnia
Status: NOT_YET_RECRUITING
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Ramelteon placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on the Effectiveness and Safety of Remote Control of Domestic Surgical Robot System for Urinary Surgery
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Adrenal Tumor|Nonfunctioning Kidney
Interventions: DEVICE: telesurgery by domestic robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Men
Status: COMPLETED
Conditions: Immune Response|Inflammation
Interventions: DIETARY_SUPPLEMENT: Almond group|DIETARY_SUPPLEMENT: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lonsurf® (Trifluridine/Tipiracil) Plus Chemotherapy in Metastatic Colorectal Cancer Prospective Study in Taiwan
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Trifluridine/tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DE-eSCALation of Opioids Post-surgical dischargE
Status: RECRUITING
Conditions: Opioid Dependence
Interventions: OTHER: Rapid Opioid de-escalation|OTHER: Gradual Opioid de-escalation|OTHER: Continuation of opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Telaprevir Plus Standard of Care (SOC) in HCV Associated Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Infection
Interventions: DRUG: Pegylated Interferon Alfa 2a|DRUG: Ribavirin|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Erythroid Leukemia (M6)|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monoblastic Leukemia and Acute Monocytic Leukemia (M5)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Childhood Acute Basophilic Leukemia|Childhood Acute Eosinophilic Leukemia|Childhood Acute Erythroleukemia (M6)|Childhood Acute Megakaryocytic Leukemia (M7)|Childhood Acute Minimally Differentiated Myeloid Leukemia (M0)|Childhood Acute Monoblastic Leukemia (M5a)|Childhood Acute Monoblastic Leukemia and Acute Monocytic Leukemia (M5)|Childhood Acute Monocytic Leukemia (M5b)|Childhood Acute Myeloblastic Leukemia With Maturation (M2)|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)|Childhood Acute Myelomonocytic Leukemia (M4)|Childhood Myelodysplastic Syndromes|de Novo Myelodysplastic Syndromes|Untreated Adult Acute Myeloid Leukemia|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: valspodar|BIOLOGICAL: filgrastim|DRUG: busulfan|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|BIOLOGICAL: aldesleukin|OTHER: clinical observation|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Sodium Stibogluconate (Pentostam) for Cutaneous and Mucocutaneous New World Leishmaniasis
Status: NO_LONGER_AVAILABLE
Conditions: Leishmaniasis, Cutaneous|Leishmaniasis, Mucocutaneous
Interventions: DRUG: sodium stibogluconate (Pentostam)
Study Type: EXPANDED_ACCESS
Clinical trial: A Study of TQB2450 in Subjects With Stage III Non-Small Cell Lung Cancer(NSCLC)
Status: RECRUITING
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: DRUG: TQB2450|DRUG: Anlotinib|DRUG: TQB2450(blank)|DRUG: Anlotinib(blank)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Kinds of Postoperative Analgesia After Amputation
Status: UNKNOWN
Conditions: Pain|Complications
Interventions: PROCEDURE: Local analgesic|PROCEDURE: Intravenous analgesic|DRUG: ropivacaine|DRUG: flurbiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Safety and Effectiveness of Two Different Kinds of Stent System in Intracranial Aneurysms
Status: RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: SINOMED IAS Stent System|DEVICE: Neuroform Atlas Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia
Status: RECRUITING
Conditions: Acute Myeloid Leukaemia
Interventions: DRUG: Gemtuzumab ozogamicin|DRUG: Liposomal daunorubicin|DRUG: Mitoxantrone|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Busulfan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Training for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: AMP|BEHAVIORAL: Applied Relaxation (AR)|BEHAVIORAL: Clinical Monitoring (CM)|BEHAVIORAL: Combining the AMP and AR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Fluciclovine Uptake in Patients With Cervical, Ovarian Epithelial or Endometrial Cancers.
Status: UNKNOWN
Conditions: Cervical Cancer|Endometrial Cancer|Ovarian Epithelial Cancer
Interventions: DRUG: Fluciclovine F18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Famotidine Compared With Pantoprazole to Prevent Recurrent Aspirin-Induced Peptic Ulcer/Erosion
Status: COMPLETED
Conditions: Peptic Ulcer/Erosions
Interventions: DRUG: pantoprazole vs famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Different Exercise Approaches on Balance and Proprioception in Individuals With Pes Planus
Status: COMPLETED
Conditions: Pes Planus
Interventions: OTHER: Mobility and Stability Exercise|OTHER: Stretching Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Melatonin on Mortality in Adult Patients Admitted to the Intensive Care Unit With COVID-19
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2|Coronavirus Infection
Interventions: DRUG: Melatonin intravenous|DRUG: Placebo intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transdermal Microneedle Patch for Topical Anesthesia Enhancement in Paediatric Thalassemia Patients
Status: COMPLETED
Conditions: Thalassemia in Children
Interventions: DEVICE: Microneedle|DRUG: 1 Finger Tip Unit (FTU) EMLA Cream (30-minute application time)|DRUG: 1 Finger Tip Unit (FTU) EMLA (15-minute application time)|DRUG: 0.5 Finger Tip Unit (FTU) EMLA (30-minute application time)|DEVICE: Sham Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Massage Between Sets of an Intense Isokinetic Exercise- Protocol of Knee Extensors in Tae Kwon Do Athletes
Status: COMPLETED
Conditions: Athletic Performance
Interventions: OTHER: Isokinetic intense exercise protocol|OTHER: Massage treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients
Status: COMPLETED
Conditions: Corneal Perforation|Exposure Keratitis|Infectious Keratitis
Interventions: COMBINATION_PRODUCT: OmniLenz®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation Using Virtual Reality During Surgery Under Spinal Anesthesia
Status: COMPLETED
Conditions: Sedation|Spinal Anesthesia
Interventions: OTHER: Sedation by watching virtual reality sedative program|PROCEDURE: Sedation by using intravenous sedative|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Progerinin in Healthy Volunteers
Status: COMPLETED
Conditions: Hutchinson-Gilford Progeria Syndrome|Werner Syndrome
Interventions: DRUG: Progerinin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of Oral Ketamine for Acute Pain Management After Amputation Surgery
Status: TERMINATED
Conditions: Acute Pain Management|Analgesic, Nonopioid|Amputation of Lower Extremity, All Causes
Interventions: DRUG: Oral Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-medication in Pain Measures on Office Hysteroscopy
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Placebo Oral + Placebo Oral|DRUG: Diclofenac oral + Placebo Oral|DRUG: Diclofenac oral + scopolamina oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane (ESP) Block in Juvenile Idiopathic Scoliosis Surgery
Status: RECRUITING
Conditions: Juvenile Idiopathic Scoliosis, Multiple Sites in Spine
Interventions: PROCEDURE: Erector spinale block (ESP block)|PROCEDURE: AG + sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prednisone on Atherogenesis as Studied in the Macrophage Foam Cell Formation Model System.
Status: COMPLETED
Conditions: Atherosclerosis|Dyslipidemias|Diabetes
Interventions: DRUG: Prednisone 20 Mg|DRUG: Prednisone 40 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Effects of Ultrasound Guided PEC Blocks on Analgesic Opioid Consumption of Cancer Surgery Patients
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: PROCEDURE: PECS Block|DRUG: Bupivacaine 0.25-0.5%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining Medications to Enhance Depression Outcomes
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRI + placebo|DRUG: Escitalopram + Bupropion SR|DRUG: Venlafaxine XR + Mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dexmedetomidine in Preventing Contrast Induced Nephropathy
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9 % NaCl|DRUG: 0.9 % NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quetiapine Sr as Adjunctive Treatment In Mixed States of Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: quetiapine SR|DRUG: quetiapine sr placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of Two Oral Formulations of Clopidogrel
Status: TERMINATED
Conditions: Comparative Bioavailability of Clopidogrel Tablets
Interventions: DRUG: Clopidogrel bisulfate|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Effectiveness of LLLT and ESWT in Plantar Fasciitis Treatment
Status: UNKNOWN
Conditions: Plantar Fascitis
Interventions: OTHER: Home Exercise Program|OTHER: Low-Level Laser Therapy (LLLT)|OTHER: Extracorporeal Shockwave Therapy (ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy With Combination Chemotherapy in Patients With Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: levamisole hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Persantin Preceding Elective PCI
Status: COMPLETED
Conditions: Coronary Heart Disease|Percutaneous Transluminal Coronary Angioplasty|Atherosclerosis
Interventions: DRUG: dipyridamole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quarfloxin in Patients With Low to Intermediate Grade Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Carcinoid Tumor
Interventions: DRUG: Quarfloxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NBMI Treatment in Patients With Atypical Parkinsons (PSP or MSA)
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Multiple System Atrophy
Interventions: DRUG: NBMI|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Small Catheter Drainage With Chest Tube Versus Chest Tube Alone After Uniport Video-assisted Thoracoscopic Procedures
Status: UNKNOWN
Conditions: Lung Diseases
Interventions: DEVICE: central venous catheter (small catheter drainage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT