pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Management of Patients With Respiratory Symptoms in Sweden
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Person in the case is a male.|OTHER: Person in the case is a female.|OTHER: Symptom in the case is breathlessness.|OTHER: Symptom in the case is pain.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Gemcitabine|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts
Status: ENROLLING_BY_INVITATION
Conditions: Seemingly Healthy|Genetic Predisposition to Disease
Interventions: GENETIC: Genomic Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhanced Broccoli Consumption After a Liking Norm and Vegetable Variety Message: Effects After a 24 Hour Delay.
Status: COMPLETED
Conditions: Eating Behaviour
Interventions: BEHAVIORAL: Neutral Control Condition|BEHAVIORAL: Food-based Control Condition|BEHAVIORAL: Health Condition|BEHAVIORAL: Descriptive Social Norm|BEHAVIORAL: Liking Social Norm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: High-dose, Short-term Steroid and Low-dose Long-term Steroid Use in ARDS Caused by COVID-19
Status: UNKNOWN
Conditions: Short-term (3 Days) High-dose (1000 mg) Systemic Methylprednisolone
Interventions: BEHAVIORAL: systemic methylprednisolone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccination Priming and Vaccine Boosting Trial of Allogeneic Human GM-CSF Gene Transduced Irradiated Prostate Cancer Cell Vaccines (GVAX® Vaccine for Prostate Cancer)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Immunotherapy allogeneic GM-CSF secreting cellular vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Control Group - ESP block with SAP block|DRUG: Treatment Group - ESP block with SAP normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence, Characteristics and Risk Factors of HIV-Associated Neurocognitive Disorders in Subjects Between the Ages of 55 and 70 Years: An Exposed/Unexposed Cross Sectional Study
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: OTHER: Health related quality of life and social and demographic informations|OTHER: Neurocognitive assessment|RADIATION: cerebral images sub-study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety, Tolerability, PK and Preliminary Activity Study of GB263T in Advanced NSCLC and Other Solid Tumor
Status: RECRUITING
Conditions: NSCLC|Other Solid Tumors
Interventions: BIOLOGICAL: GB263T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Bioequivalence of Lacosamide 200mg Administered as Intravenous Solution and Oral Tablet in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Healthy Male Chinese Volunteers
Interventions: DRUG: Lacosamide (LCM) tablet|DRUG: Lacosamide (LCM) solution for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Neoplasms|Gallbladder Cancer|Cholangiocarcinoma
Interventions: DRUG: Durvalumab + Gem/Cis|DRUG: Gem/Cis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IO Vancomycin in TSA
Status: RECRUITING
Conditions: Shoulder Injuries
Interventions: DRUG: Intervention - Intraosseous (IO) administration of vancomycin|DRUG: Control - Standard IV administration of vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IDN-6556 in Subjects With NAFLD and Raised Transaminases
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis|Non-alcoholic Fatty Liver Disease
Interventions: DRUG: IDN-6556|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Induction of Labor in Term Pregnancies With Unfavourable Cervix
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn|Prostaglandins Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Dinoprostone 0.5 MG|DRUG: Dinoprostone 2 MG/2.5 ML Vaginal Gel/Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
Status: COMPLETED
Conditions: Neoplastic Meningitis
Interventions: DRUG: Topotecan|DRUG: Topotecan|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hepatitis B Virus Antibody Booster Program for the Production of Hepatitis B Immune Globulin (HBIG)
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: hepatitis B vaccine|BIOLOGICAL: hepatitis B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Complex Percutaneous Pulmonary Vein Isolation Combined With Left Atrial Appendage Occluder Implantation for Patients With Cardiogenic Ischemic Stroke in the Course of Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Atrial Fibrillation
Interventions: PROCEDURE: PVI + LAAO|PROCEDURE: LAAO|DRUG: NOAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Fasiglifam (TAK-875)|DRUG: Fasiglifam (TAK-875) Placebo|DRUG: Sitagliptin|DRUG: Sitagliptin Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)
Status: COMPLETED
Conditions: Graft vs Host Disease|Immune System Disorders
Interventions: DRUG: Etanercept|DRUG: Mycophenolate Mofetil|DRUG: Denileukin Diftitox|DRUG: Pentostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)
Status: WITHDRAWN
Conditions: Leukemia
Interventions: PROCEDURE: ROR1R-CAR-T Cell Infusion|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLM
Status: TERMINATED
Conditions: Colorectal Cancer|Liver Metastases|HAI
Interventions: DRUG: FUDR|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: 5FU|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorambucil or Fludarabine as First-Line Therapy in Treating Patients With Previously Untreated Waldenström Macroglobulinemia, Splenic Lymphoma, or Lymphoplasmacytic Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: chlorambucil|DRUG: fludarabine phosphate|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Heart rate variability biofeedback|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Investigate the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of CJ-12406 in Healthy Male Subjects
Status: COMPLETED
Conditions: Digestive System Diseases
Interventions: DRUG: Placebo|DRUG: CJ-12406
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Hypnosis in Guided Hepatic Biopsy (Ap-Hy-PBH)
Status: COMPLETED
Conditions: Ultrasound-guided Hepatic Biopsy
Interventions: BEHAVIORAL: Hypnoanalgésia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia
Status: COMPLETED
Conditions: Contraception|Family Planning|Task Shifting|Community Based Distribution|DMPA
Interventions: OTHER: Community Based administration of DMPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraoperative Lung Protective Ventilation Needs Periodic Lung Recruitment Maneuvers
Status: RECRUITING
Conditions: Postoperative Complications|Abdominal Surgery|Intraoperative Mechanical Ventilation
Interventions: OTHER: periodic lung recruitment maneuvers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Sonographic Efficacy of Rituximab in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DEVICE: ESAOTE MyLab60|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The State of Sexual Development in Children With Inherited Epidermolysis Bullosa
Status: UNKNOWN
Conditions: Dermatologic Disease|Epidermolysis Bullosa|Epidermolysis Bullosa Simplex|Epidermolysis Bullosa Dystrophica|Epidermolysis Bullosa, Junctional|Kindler Syndrome|Puberty Disorders|Hormone Disturbance
Interventions: DIAGNOSTIC_TEST: Biochemical study of hormone levels|DIAGNOSTIC_TEST: Ultrasound examination|RADIATION: Radiography of the hands|BEHAVIORAL: Consultation of a medical psychologist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Golimumab Phase 3b, Multicenter, Assessment of Intravenous Efficacy in Rheumatoid Arthritis Subjects Who Have Diminished Disease Control Despite Treatment With Infliximab (REMICADE®)
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: Golimumab 2 mg/kg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tomography Positron Emission Assessment of the Impact of Cardiac Rehabilitation on Coronary Endothelial Function in Cardiac Failure
Status: COMPLETED
Conditions: Cardiac Failure
Interventions: PROCEDURE: cardiac Rehabilitation|OTHER: Tomography Positron Emission
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Ticagrelor in Patients Undergoing Carotid Stenting
Status: UNKNOWN
Conditions: Carotid Stenosis
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel|PROCEDURE: Carotid stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bodily Illusion and tDCS on SCI-related Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: OTHER: Bodily Illusions (BI) Procedure|DEVICE: Transcranial direct electrical stimulation (tDCS)|OTHER: Sham Transcranial Direct Electrical Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Clinical Evaluation of Three Prosthesis Re-cap, M2a-Magnum and C2a-taper.
Status: COMPLETED
Conditions: Patients Undergoing a THR
Interventions: DEVICE: Hip prosthesis (re-cap, m2a-magnum and C2a-taper)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Supporting CHWs as Vaccine Educators: Impact of a Digital Training and Chatbot Intervention on Vaccination in Kenya
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccine Knowledge|Vaccine Hesitancy|Vaccine Refusal
Interventions: BEHAVIORAL: Digital Vaccine Education Training & Patient-facing Chatbot Tool|BEHAVIORAL: Standard Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Infant- Toddler Climate of Healthy Interactions for Learning and Development (I-T CHILD)
Status: COMPLETED
Conditions: Child Development|Child Behavior|Social Skills|Infant Development
Interventions: OTHER: I-T CHILD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine and Comprehensive, Individualized Management of Alzheimer's Disease and Caregiver Training
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BEHAVIORAL: Individualized management of AD including caregiver training|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Therapeutic Effects and Effects on Body Fat of GLP-1 Receptor Agonists in Patients With Type 2 Diabetes for 1-4 Years
Status: RECRUITING
Conditions: Diabetes
Interventions: DRUG: Duragtide, Semaglutide, losenatide, tirzepatide, ebenatide, etc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Ductal Breast Carcinoma In Situ|Invasive Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Sporadic Breast Carcinoma
Interventions: OTHER: Decision Aid|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemostatic Endothelial Dysfunction in Patients With Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Artery Disease|Restenosis of Peripheral Vascular Stent|Restenosis, Vascular Graft|Endothelial Dysfunction
Interventions: PROCEDURE: an arterial reconstructive procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Tegoprazan Based Bismuth Quadruple Therapy for Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Tegoprazan|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: ChloraPrep|DRUG: 0.1% Sodium Lauryl Sulfate|DRUG: 0.9% Physiological Saline|OTHER: ZuraPrep without IPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Efficacy and Safety of CD47 Monoclonal Antibody Combined With Azacitidine in the Treatment of Recurrent AML After Transplantation
Status: UNKNOWN
Conditions: Patients With Recurrent Acute Myelogenous Leukemia After Transplantation
Interventions: DRUG: CD47 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling
Status: WITHDRAWN
Conditions: Pathological Gambling
Interventions: BEHAVIORAL: CRAFT treatment|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control
Status: UNKNOWN
Conditions: Myopia, Progressive|Refractive Errors|Eye Diseases
Interventions: DEVICE: Ortho-k lenses|DEVICE: RLRL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canine Retraction With Temporary Anchorage Devices
Status: COMPLETED
Conditions: Class II Malocclusion|Class III Malocclusion|Crowding, Tooth|Bimaxillary Protrusion
Interventions: PROCEDURE: canine retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravital Microscopy in Identifying Tumor Vessels in Patients With Stage IB-IIIC Melanoma Undergoing Sentinel Lymph Node Biopsy
Status: COMPLETED
Conditions: Stage IB Skin Melanoma|Stage IIA Skin Melanoma|Stage IIB Skin Melanoma|Stage IIC Skin Melanoma|Stage IIIA Skin Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma
Interventions: PROCEDURE: Diagnostic Microscopy|DRUG: Fluorescein Sodium Injection|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Sentinel Lymph Node Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety and Kinetics Study of Octagam 10% in Primary Immunodeficiency Diseases
Status: TERMINATED
Conditions: Immunologic Deficiency Syndromes
Interventions: DRUG: Octagam 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Bicalutamide for Recurrent pT3N0 Prostate Cancer After Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: bicalutamide|RADIATION: radiation therapy|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia AML|Myelodysplastic Syndrome MDS
Interventions: DRUG: Vidaza and Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumor|Anaplastic Thyroid Cancer|Adenocarcinoma|Pheochromocytoma|Paraganglioma
Interventions: DRUG: Cabozantinib 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Brimonidine to Reduce Inflammation After IPL-treatment in Patients With Facial Telangiectasias
Status: COMPLETED
Conditions: Telangiectasias
Interventions: DRUG: Brimonidine|OTHER: IPL+air-cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Flu mRNA|COMBINATION_PRODUCT: Control 1|COMBINATION_PRODUCT: Control 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Protein Supplementation on Fat Free Mass Preservation After Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery Candidate|Protein Deficiency|Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Protein drink supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Difference in Subclavian Vein Catheterization Between Supine and Lateral Tilt Position - Stage II
Status: UNKNOWN
Conditions: Catheterization|Posture
Interventions: PROCEDURE: Ipsilateral tilt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and PK Study of BIBF 1120 in Japanese Patients With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Placebo|DRUG: BIBF 1120|DRUG: BIBF 1120|DRUG: BIBF 1120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Quantitative Sensory Testing of the Lower Lip After Inferior Alveolar Nerve Block, and Evaluation of the Role of the Contra-lateral Inferior Alveolar Nerve
Status: TERMINATED
Conditions: Healthy
Interventions: PROCEDURE: Temporary blocking of mandibular nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile CBT for Negative Symptoms
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Mobile-assisted CBT-informed Skills Training|BEHAVIORAL: Supportive Contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Treatment for Adolescent Anorexia Nervosa
Status: COMPLETED
Conditions: Eating Disorder|Anorexia|Anorexia Nervosa|Anorexia in Adolescence|Anorexia in Children|Anorexia Nervosa Restricting Type|Anorexia Nervosa, Atypical|Eating Disorders in Adolescence
Interventions: BEHAVIORAL: Family Based Treatment|BEHAVIORAL: Family Based Treatment + Intensive Parental Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Specimens and Clinical Data for Patients With Recurrent or Metastatic Breast Cancer or Male Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma|Metastatic Breast Carcinoma|Recurrent Breast Carcinoma
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Upper Limb Ergometer on the AIP in Post Menopausal Obese Women.
Status: COMPLETED
Conditions: Post Menopausal Obese Women
Interventions: DEVICE: Electronic Upper limb( body) ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MT-12 Implant Survival and Marginal Bone Loss
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: MT-12 dental implant|DEVICE: CON.INT dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study to Test the Safety and Preliminary Efficacy of PPSGG in Patients With Anti-MAG Neuropathy
Status: TERMINATED
Conditions: Anti-MAG Neuropathy
Interventions: DRUG: PPSGG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide
Status: TERMINATED
Conditions: Pulmonary Hypertension|Lung Disease|Sickle Cell Disease|Cardiac Transplant|Lung Transplant
Interventions: DRUG: Inhaled Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiotherapy for Resected Hepatocellular Carcinoma With MVI
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Maintenance for SCLC
Status: COMPLETED
Conditions: SCLC
Interventions: DRUG: Pazopanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline In Pediatric Acute Lymphoblastic Leukemia During Induction
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Pentoxifylline Plus Chemotherapy|DRUG: Placebo Plus Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: AMG 162|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Tampons as a Biospecimen Collection Tool for the Detection of Human Papillomavirus in a Colposcopy Setting
Status: NOT_YET_RECRUITING
Conditions: CIN2
Interventions: DEVICE: Daye Diagnostic Tampon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of mRNA-1018 Pandemic Influenza Candidate Vaccines in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: mRNA-1018 for H5N8|BIOLOGICAL: mRNA-1018 for H7N9|BIOLOGICAL: mRNA-1018 for H5 Only|BIOLOGICAL: mRNA-1018 for H7 Only|BIOLOGICAL: mRNA-1018 for H5 Only-CG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma
Status: UNKNOWN
Conditions: pH
Interventions: DRUG: Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Wire Assisted Percutaneous Balloon Mitral Valvulotomy With Standard Inoue Balloon Valvulotomy
Status: COMPLETED
Conditions: Rheumatic Heart Disease
Interventions: DEVICE: Percutaneous Balloon Mitral Valvulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Method Development Study to Characterise The Efficacy of a Dentifrice For The Relief Of Dentin Hypersensitivity
Status: WITHDRAWN
Conditions: Dentin Sensitivity
Interventions: DRUG: Dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride).|DRUG: Dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring in Pulmonary Rehabilitation: Feasibility and Acceptability of a Remote Pulse Oxymetry System.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Rehabilitation|Telemedicine
Interventions: OTHER: Rehabilitation using telehealth technology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sub-clinical Inflammation and Iron Supplementation
Status: COMPLETED
Conditions: Anemia
Interventions: DIETARY_SUPPLEMENT: Iron group|DIETARY_SUPPLEMENT: Vitamin A group|DIETARY_SUPPLEMENT: Iron and vitamin A group|DIETARY_SUPPLEMENT: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral and Vaginal Misoprostol for Induction of Labor in Nulliparous Pregnant Women
Status: NOT_YET_RECRUITING
Conditions: Misoprostol|Labor|Nulliparous|Pregnancy
Interventions: DRUG: Vaginal Misoprostol|DRUG: Oral Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Needle Size and Pain Perception With Botulinum Toxin A Injections
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: 30-gauge needle|PROCEDURE: 32-gauge needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 2a Study To Evaluate The Pharmacokinetics, Safety, Efficacy, Tolerability, And Pharmacodynamics of Sotatercept (ACE-011) for the Correction of Anemia in Subjects With End-stage Renal Disease on Hemodialysis.
Status: COMPLETED
Conditions: Anemia
Interventions: BIOLOGICAL: Sotatercept|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Extraesophageal Reflux on Inferior Nasal Turbinates Hypertrophy
Status: COMPLETED
Conditions: Inferior Nasal Turbinate Hypertrophy|Extraesophageal Reflux
Interventions: DIAGNOSTIC_TEST: 24-hour monitoring of oropharyngeal pH by Restech, RYAN scores upright and supine, and pH values <5.5 will be evaluated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VITamin D and OmegA-3 TriaL: Effects on Mammographic Density and Breast Tissue
Status: UNKNOWN
Conditions: Benign Breast Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D and fish oil placebo|DIETARY_SUPPLEMENT: Fish oil and vitamin D placebo|DIETARY_SUPPLEMENT: Vitamin D placebo and fish oil placebo|DIETARY_SUPPLEMENT: Vitamin D and fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion
Status: COMPLETED
Conditions: Pain|Pregnancy
Interventions: DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Coxarthrosis|Arthroplasties Hip Replacement|Perioperative Blood Loss
Interventions: DRUG: Etoricoxib|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling
Status: ACTIVE_NOT_RECRUITING
Conditions: Dietary Protein
Interventions: DIETARY_SUPPLEMENT: Dietary protein shake
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Hetrombopag in Healthy Subjects
Status: COMPLETED
Conditions: Sever Aplastic Anaemia
Interventions: DRUG: Hetrombopag Olamine Tablet；Ciclosporin Soft Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Access in Dialysis for Better Outcomes in Patient Therapy
Status: COMPLETED
Conditions: Central Venous Catheter|Catheter-Related Bloodstream Infection (CRBSI) Nos
Interventions: DEVICE: BioFlo DuraMax Chronic Hemodialysis Catheter|DEVICE: Standard of Care Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cytarabine|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Medication Self-Administration and Health After Brain Injury
Status: UNKNOWN
Conditions: Stroke|Stroke, Acute|Cognitive Impairment|Brain Injuries, Traumatic|Medication Adherence|Medication Compliance
Interventions: OTHER: Video Call Reminder Condition|OTHER: Automated Text Message Reminder Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: JNJ-54861911, 10 milligram (mg)|DRUG: JNJ-54861911, 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of STAR (Sensory Therapies and Research) Intervention for School-Based Occupational Therapy Services for Students With Sensory Processing Challenges
Status: COMPLETED
Conditions: Sensory Processing Disorder
Interventions: OTHER: Sensory Integration Intervention through the STAR Frame of Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stethee® to the Conventional Stethoscope for Auscultation of Simulated Heart Sounds
Status: COMPLETED
Conditions: Heart Diseases
Interventions: DEVICE: Stethee®|DEVICE: 3MTM Littmann® Classic IIITM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Biodistribution and Safety of 123-I MZINT in Healthy Subjects and Parkinson Disease Patients
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: [123I] mZINT injection and serial dynamic SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neratinib in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Metastatic Prostate Adenocarcinoma|Castration-resistant Prostate Cancer|Prostate Cancer|Prostate Cancer Metastatic
Interventions: DRUG: Neratinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dermal Closure With an Absorbable Barbed Suture as Compared to a Conventional Absorbable Suture
Status: COMPLETED
Conditions: Breast Ptosis|Obesity
Interventions: DEVICE: V-Loc 180/90 Wound Closure Device|DEVICE: 3-0 Monocryl Absorbable Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Ezetimibe|DRUG: Placebo (for Alirocumab)|DRUG: Placebo (for Ezetimibe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real Time Ultrasound Guided Spinal Anesthesia in Elderly Patients
Status: COMPLETED
Conditions: Realtime Ultrasound
Interventions: DEVICE: Parasagittal oblique technique (Ultrasound)|DEVICE: Paramedian tranverse technique (Ultrasound)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China
Status: TERMINATED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aging on Micro-tensile Bond Strength and Color Stability of Self-adhesive Resin Composite
Status: RECRUITING
Conditions: Tooth Decay
Interventions: OTHER: self-adhesive resin restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Antiproteinuric Effect of Valsartan and Lisinopril
Status: COMPLETED
Conditions: Hypertension|Diabetic Nephropathy
Interventions: DRUG: Valsartan|DRUG: Valsartan plus HCTZ|DRUG: Lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Brentuximab Vedotin as Therapy After Autologous Stem Cell Transplant in Cluster of Differentiation Antigen 30 (CD30) Positive Peripheral TCell Lymphomas
Status: WITHDRAWN
Conditions: T Cell Lymphoma
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Red Ginseng Extract on Changes in Indicators of Immune Function in Vietnamese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: KRG hard capsule|DRUG: Placebo hard capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amifostine for Head and Neck Irradiation in Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Hodgkin's Disease|Non-Hodgkin's Lymphoma
Interventions: DRUG: Amifostine|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)
Status: COMPLETED
Conditions: Diabetes Mellitus|Coronary Artery Disease
Interventions: DRUG: prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Energy Metabolism in Undernourished Patients With Gastrointestinal Cancer
Status: COMPLETED
Conditions: Undernutrition|Gastrointestinal Cancer
Interventions: OTHER: Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bifocal Lenses In Nearsighted Kids
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Biofinity Multifocal D +1.50 add|DEVICE: Biofinity Multifocal D +2.50 add|DEVICE: Biofinity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer
Status: COMPLETED
Conditions: Attenuated Familial Adenomatous Polyposis|Familial Adenomatous Polyposis
Interventions: DRUG: Erlotinib|DRUG: Erlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children
Status: TERMINATED
Conditions: Lumbar Puncture|Topical Analgesia
Interventions: DEVICE: J-Tip|DRUG: EMLA|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Gluten-free Diet on Quality of Life in Patients With Axial Spondyloarthritis.
Status: RECRUITING
Conditions: Ankylosing Spondyloarthritis
Interventions: DIETARY_SUPPLEMENT: Gluten-Free Diet|DIETARY_SUPPLEMENT: Gluten Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 0.005% Sodium Hypochlorite Final Rinse Solution in Atopic Dermatitis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Sodium Hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ANI-guided Intraoperative Analgesia vs Conventional Intraoperative Analgesia
Status: COMPLETED
Conditions: Postoperative Pain|Analgesia|Surgery
Interventions: PROCEDURE: ANI-guided intraoperative analgesia|PROCEDURE: Conventional intraoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Manual Toothbrushes in Removing Tooth Stains
Status: NOT_YET_RECRUITING
Conditions: Tooth Discoloration
Interventions: DRUG: NaF|DRUG: Na MFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Socioeconomic Determinants on the Patient Reported Outcomes in Young Breast Cancer Patients After Breast Surgery
Status: RECRUITING
Conditions: Breast Cancer|Surgery|Quality of Life
Interventions: PROCEDURE: Breast-conserving surgery|PROCEDURE: Mastectomy|PROCEDURE: Mastectomy with reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tucatinib+Trastuzumab+Eribulin in HER2+ MBC
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tucatinib|DRUG: Eribulin|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hip
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: DRUG: FX006 32 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Heterotopic Implantation Of the Edwards-Sapien Transcatheter Aortic Valve in the Inferior VEna Cava for the Treatment of Severe Tricuspid Regurgitation (HOVER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: Heterotopic Implantation Of the Edwards-Sapien XT Transcatheter Valve in the Inferior VEna Cava
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT