pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial
Status: COMPLETED
Conditions: Bipolar Disorder|Involutional Depression|Mood Disorder
Interventions: DRUG: Ethyl Eicosapentaenoic Acid|DRUG: OmegaBrite
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity
Status: UNKNOWN
Conditions: Post Stroke Upper Limb Spasticity
Interventions: BIOLOGICAL: HU-014 Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Coenzyme A on Serum Lipids in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipoproteinemia
Interventions: DRUG: Coenzyme A|DRUG: Coenzyme A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Tomography (PET) Study to Assess the Degree of Dopamine-2 (D2) Receptor Occupancy in the Human Brain After Single Doses of BL-1020 or Perphenazine in Healthy Male Subjects Using [11C]Raclopride as PET Tracer
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BL 1020|DRUG: Perphenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Biodistribution Study With 186 Re-labelled Humanised Monoclonal Antibody BIWA 4 in Patients With Adenocarcinoma of the Breast
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: DRUG: BIWA 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of Lower Urinary System Symptoms With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy|Lower Urinary Tract Symptoms|Muscle Weakness|Posture Disorders in Children|Lumbar Lordosis|Pelvic Floor Muscle Weakness|Quality of Life
Interventions: DEVICE: Baseline Bubble Inclinometer, Baseline Digital İnclinometer and Hoggan microFET2 devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sensorimotor Training for Adults With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Neuropathy|Somatosensory Disorders|Sensorimotor Gait Disorder
Interventions: BEHAVIORAL: sensorimotor training based on Feldenkrais method|BEHAVIORAL: foot care education|COMBINATION_PRODUCT: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation Study of Long-term Safety, Tolerability, Pharmacokinetics and Efficacy of Recifercept in Achondroplasia
Status: TERMINATED
Conditions: Achondroplasia
Interventions: BIOLOGICAL: Recifercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners
Status: UNKNOWN
Conditions: Prostate Cancer|Psychosocial Effects of Cancer and Its Treatment|Sexual Dysfunction and Infertility|Sexuality and Reproductive Issues
Interventions: OTHER: communication intervention|OTHER: counseling intervention|OTHER: questionnaire administration|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Trial of IW-9179 in Patients With Diabetic Gastroparesis (DGP)
Status: COMPLETED
Conditions: Diabetic Gastroparesis
Interventions: DRUG: IW-9179|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UK
Status: UNKNOWN
Conditions: Malaria|Plasmodium Falciparum
Interventions: BIOLOGICAL: Pfs48/45 in Matrix-M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Human Requirements for the Nutrient Choline
Status: COMPLETED
Conditions: Postmenopausal Women
Interventions: OTHER: Estrogen plus choline depletion diet|OTHER: Placebo plus choline depletion diet|OTHER: Pre-menopausal women with SNPs given a low choline diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Tranexamic Acid (TXA) in Hip Arthroscopy
Status: WITHDRAWN
Conditions: Hip Pain Chronic|Hip Impingement Syndrome|Hip Injuries|Blood Loss|Femoro Acetabular Impingement
Interventions: DRUG: Tranexamic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of CSII and MDI in Pediatric Patients With Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: DIA:CONN G8 insulin pump|OTHER: Multiple daily insulin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-1 Versus S-1 Plus Cisplatin as an Adjuvant Chemotherapy to Treat Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: S-1|DRUG: S-1 plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterisation of 24-hour FEV1-time Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744 (Olodaterol) Low Dose|DRUG: BI 1744 (Olodaterol) Medium Dose|DRUG: Placebo|DRUG: Foradil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Biomarker of DONQ52 in Celiac Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Celiac Disease
Interventions: DRUG: DONQ52|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Integrated Face-to-face Rehabilitation and Telerehabilitation on the Well-being of Family Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregivers|Family Caregivers|Informal Caregivers
Interventions: OTHER: Integrated face-to-face rehabilitation and telerehabilitation|OTHER: Social Holidays|OTHER: Face-to-face rehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors
Status: TERMINATED
Conditions: Cancer Survivor|No Evidence of Disease|Obesity|Overweight|Prostate Carcinoma|Sedentary Lifestyle|Stage I Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|DEVICE: Monitoring Device|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischemic Conditioning in Adult Moyamoya Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Moyamoya Disease|Remote Ischemic Conditioning
Interventions: DEVICE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macintosh and D-Blade® in Simulated Difficult Airway
Status: COMPLETED
Conditions: Difficult Intubation|Cervical Injury Spine
Interventions: DEVICE: Macintosh blade|DEVICE: D-Blade|DEVICE: Intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Antioxidant Intake on Cardiovascular Risk
Status: COMPLETED
Conditions: Effect of Resveratrol and Curcumin on Inflammation
Interventions: DIETARY_SUPPLEMENT: Resveratrol, curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC).
Status: COMPLETED
Conditions: Opioid Induced Constipation
Interventions: DRUG: Laxative
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I-II Dose Escalation Study of Stereotactic Body Radiation Therapy in Patients With Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Rehabilitation Via Telemonitoring in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Telerehabilitation|OTHER: Hospital based Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients
Status: COMPLETED
Conditions: Uterine Atony With Hemorrhage
Interventions: DRUG: Methylergonovine|DRUG: Normal Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide and Nivolumab in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Nivolumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Vitamin D Supplementation for ADT-induced Side Effects
Status: COMPLETED
Conditions: Prostatic Neoplasms|Bone Mineral Density Quantitative Trait Locus 3
Interventions: DIETARY_SUPPLEMENT: vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Flexibility, Gut Microbiota, Healthy Diet and Exercise in NAFLD on Genetics Base
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease|Obesity
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet|DIETARY_SUPPLEMENT: Low fat diet|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Influence of Clinical Pharmacist on the Quality of Drug Prescribing and Rehabilitation Outcomes in Post-acute Hip Fractured Patients
Status: COMPLETED
Conditions: Hip Fractures|Clinical Pharmacists|Rehabilitation Outcome
Interventions: OTHER: Pharmaceutical intervention|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Parenting Young Children Check-up Evaluation
Status: COMPLETED
Conditions: Disruptive Behavior|Parenting
Interventions: BEHAVIORAL: The Parenting Young Children Check-up Initial Check-up and Text Messages|BEHAVIORAL: The Parenting Young Children Check-up Flier and Text Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty (THA): Early Load Versus Load Late
Status: UNKNOWN
Conditions: Primary Total Hip Arthroplasty
Interventions: OTHER: Early loading|OTHER: Late loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Re-engagement at Discharge 2
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS|Hospitalization|Transitions of Care|Opportunistic Infections
Interventions: BEHAVIORAL: Community Health Worker Post-Discharge Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study of Hetrombopag Olamine Tablets in Adults Receiving 21-day Cycles of Chemotherapy for Solid Tumours, Who Are Delayed for at Least 1 Week From Their Scheduled Cycle Because of Chemotherapy-induced Thrombocytopenia
Status: WITHDRAWN
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Hetrombopag|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings
Status: RECRUITING
Conditions: Alcohol Use Disorder|Risky Health Behavior
Interventions: BEHAVIORAL: Female-Specific Cognitive Behavioral Therapy (FS-CBT)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial Assessing Nivolumab in Class II Expressing Microsatellite Stable Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Tolerability of a Rapeseed Food Ingredient
Status: COMPLETED
Conditions: Food Safety
Interventions: OTHER: Rapeseed ingredient (RI)|OTHER: Control product without added RI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo
Status: COMPLETED
Conditions: Joint Diseases
Interventions: DRUG: Tapentadol|DRUG: Oxycodone|DRUG: Placebo|DRUG: usual pain treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial
Status: COMPLETED
Conditions: Lumbar Spine Disc Herniation|Lumbar Radiculopathy
Interventions: PROCEDURE: Lumbar Microdiscectomy|OTHER: Physiotherapy, Epidural injections, Education, Pain Medications, Anti-inflammatories
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study: Influence of Vilaprisan on Pharmacodynamics (PD) and Pharmacokinetics (PK) of a Combined Oral Contraceptive (COC)
Status: COMPLETED
Conditions: Clinical Trial ,Phase I
Interventions: DRUG: Vilaprisan (BAY 1002670)|DRUG: Vilaprisan Placebo|DRUG: Microgynon|DRUG: Microgynon Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine tablets|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetyl-L-carnitine on Chronic Pancreatitis
Status: TERMINATED
Conditions: Chronic Pancreatitis
Interventions: DIETARY_SUPPLEMENT: acetyl-L-carnitine 1000mg 2X per day for 3 months
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Pharmacokinetics of REGN5069 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: REGN5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Pentoxifylline Gel on Behcet's Disease Oral Ulcers
Status: COMPLETED
Conditions: Behçet Disease Affecting Oral Mucosa
Interventions: DRUG: Pentoxifylline|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Use of Platelet Rich Plasma in Front Hyaluronic Acid in Coxarthrosis
Status: COMPLETED
Conditions: Coxarthrosis
Interventions: DRUG: Platelet rich plasma|DRUG: Hylan G-F 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections Development
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: OTHER: IAI infection|OTHER: Staphylococcus aureus nasal carriage infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: Daptomycin|DRUG: Vancomycin|DRUG: Ceftaroline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study About the Usefulness of Monitoring Plasma Levels of Colistin and Sodium Colistimethate in Patients With Infections Due to Multi-drug Resistant Gram Negative Bacilli, Treated With Colistin
Status: COMPLETED
Conditions: Multidrug Resistant Gram Negative Bacterial Infections
Interventions: DEVICE: Prospective TDM Arm of colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial and Clinical Efficacy of Cliradex® as Compared With I-Lid'n Lash® Hygiene in Treating Blepharitis
Status: UNKNOWN
Conditions: Blepharitis|Meibomian Gland Dysfunction
Interventions: OTHER: Tea Tree Oil (TTO)|OTHER: I-Lid'n Lash® Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With No Reperfusion Therapy (INSIST-NRT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Stroke|Neuroprotection
Interventions: DRUG: Intra-arterial administration of neuroprotective agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Independent and Combined Effects of Aerobic and Resistance Training on Blood Pressure
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Resistance Exercise|BEHAVIORAL: Combined aerobic and resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: 8-Chloroadenosine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Gastritis|Gastric Cancer
Interventions: DRUG: Amoxicillin - high dose dual therapy|DRUG: Pylera|DRUG: Esomeprazole 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypogonadism
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Complementary Feeding Counseling on Appropriate Complementary Feeding Practices and Child Undernutrition
Status: RECRUITING
Conditions: Feeding Behavior
Interventions: BEHAVIORAL: Complementary feeding counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC
Status: RECRUITING
Conditions: Oligometastatic Disease
Interventions: DRUG: IMSA101|DRUG: Immune checkpoint inhibitor|RADIATION: PULSAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citicoline in Ischemic Stroke, a Randomized Trial
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Citicoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection
Status: COMPLETED
Conditions: Acute HIV Infection|HIV Infections
Interventions: DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Using Aspirin to Improve Immunological Features of Ovarian Tumors
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Aspirin 325mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BLX-028914 in Subjects With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: BLX-028914|DRUG: BLX-028914|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Aromatherapy on Anxiety, Vital Signs, and Postoperative Complications in Lower Impacted Wisdom Tooth Surgery
Status: COMPLETED
Conditions: Tooth, Impacted|Dental Anxiety
Interventions: OTHER: Lavander Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR) (Study P04054)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: desloratadine|DRUG: fexofenadine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Enriched Plasma for Treatment of Interstitial Cystitis
Status: UNKNOWN
Conditions: Interstitial Cystitis|Bladder Pain Syndrome|Platelet Enriched Plasma
Interventions: BIOLOGICAL: platelet enriched plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation in Extremely Preterm Infants in Scandinavia
Status: RECRUITING
Conditions: Necrotizing Enterocolitis|Death|Sepsis Newborn|Feeding Disorder Neonatal|Growth Acceleration
Interventions: DIETARY_SUPPLEMENT: ProPrems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Totalis|Alopecia Universalis|Ophiasic Alopecia
Interventions: DRUG: methylprednisolone sodium succinate|DRUG: methylprednisolone sodium succinate|DRUG: methylprednisolone sodium succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CARbon Dioxide Flooding to Reduce Postoperative Neurological Injury Following Surgery for Acute Type A Aortic Dissection
Status: RECRUITING
Conditions: D000784|D020521
Interventions: PROCEDURE: Carbon dioxide flooding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Community-based Participatory Research (CBPR) Intervention for Childhood Asthma Using Air Filters and Air Conditioners
Status: COMPLETED
Conditions: Childhood Asthma
Interventions: BEHAVIORAL: Community Health Worker Intervention|OTHER: Air Filter|OTHER: Air Filter and Air Conditioner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Amodiaquine+Artesunate vs. Artemether-Lumefantrine for Uncomplicated Malaria in Ghanaian Children
Status: UNKNOWN
Conditions: Uncomplicated Malaria
Interventions: DRUG: amodiaquine+artesunate/artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetic Interactions and Safety Between Fimasartan and Rosuvastatin
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Determining the Effect of Six Weeks of Cannabis Abstinence on Fronto- Striatal fMRI Markers in Adolescents With Cannabis Use Disorder (ABSCAN)
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: CB-Abst|BEHAVIORAL: CB-Mon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AME (Absorption, Metabolism, and Excretion) of Radiolabeled SSP-004184
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Radiolabeled SPD602 (FBS0701, SSP-004184)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endostar Durative Transfusion Combined With Chemotherapy in the Treatment of Advanced Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Adenocarcinoma of Lung
Interventions: DRUG: recombinant human endostatin|DRUG: pemetrexed plus cisplatin or carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Recovery and Lifespan of Radiolabeled Autologous S303 Treated Red Blood Cells
Status: COMPLETED
Conditions: Focus: Assess Post Infusion Viability of S303 RBCs
Interventions: BIOLOGICAL: S303 Red Blood Cells (RBCs)|BIOLOGICAL: Conventional, untreated Red Blood Cells (RBCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A (5-5-5-8) Technique for Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Cholecystitis; Gallstone|Cholecystolithiasis|Cholecystitis, Chronic
Interventions: PROCEDURE: 5-5-5-8 technique|PROCEDURE: 10-10-10-5 technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAlgary SAlt for POTS
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DIETARY_SUPPLEMENT: Sodium Chloride Capsules|OTHER: Microcystalline Cellulose Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Surveillance Study to Assess Handling and Patient Satisfaction on Berodual® Respimat® Solution for Inhalation in Comparison to a Powder Inhaler in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Berodual® Respimat® - inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Incline Training to Personalize Motor Control Interventions After Stroke
Status: COMPLETED
Conditions: CVA (Cerebrovascular Accident)
Interventions: OTHER: Incline treadmill walking|OTHER: Decline treadmill walking|OTHER: Level Treadmill (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Retrofit Particle Trap on the Vascular Effects of Diesel Exhaust Inhalation
Status: COMPLETED
Conditions: Heart Disease
Interventions: PROCEDURE: Forearm Venous Occlusion Plethysmography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects
Status: COMPLETED
Conditions: Metabolic Diseases|Hyperlipidemias|Metabolic Disorder|Hypercholesterolemia|Dyslipidemias|Lipid Metabolism Disorders
Interventions: DRUG: mipomersen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections
Status: COMPLETED
Conditions: Staphylococcal Infections
Interventions: OTHER: Nasal swabs for MRSA culture|DRUG: Chlorhexidine gluconate|OTHER: Contact isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma
Status: COMPLETED
Conditions: Brain Tumor|Central Nervous System Tumor
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: vincristine sulfate|RADIATION: radiation therapy|DRUG: Mesna|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Ad26.RSV. preF-based Vaccine in Adults Aged 18 to 59 Years, Including Adults at High Risk for Severe RSV Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection Prevention
Interventions: BIOLOGICAL: Ad26.RSV.preF-based Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Tebapivat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Aerobic Training Among Adolescents With Chronic Diseases During COVID-19 Pandemic
Status: UNKNOWN
Conditions: Chronic Disease|Chronic Diseases in Adolescence|Chronic Disease of Immune System|Chronic Kidney Diseases
Interventions: OTHER: Exercise training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Erector Spinae Plane Block for the Pain Control of Thoracic Postherpetic Neuralgia
Status: WITHDRAWN
Conditions: Thoracic Postherpetic Neuralgia
Interventions: PROCEDURE: erector spinae plane block (20 mL of 0.25% ropivacaine with dexamethasone 5mg)|PROCEDURE: thoracic paravertebral block(10 mL 0.25% ropivacaine with dexamethasone 5mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Dissection of the No.253 lymph node|PROCEDURE: Omitting the dissection of the No.253 lymph node
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zonisamide Versus Propranolol in Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Zonisamide 50 MG|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventricular Tachycardia in Ischemic Cardiomyopathy; a Combined Endo-Epicardial Ablation Within the First Procedure Versus a Stepwise Approach
Status: UNKNOWN
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy
Interventions: OTHER: combined endo/epicardial approach|OTHER: stepwise approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Denosumab on Bone Mineral Density in Women With Anorexia Nervosa: A Pilot Study
Status: COMPLETED
Conditions: Bone Density|Bone Loss|Anorexia Nervosa|Eating Disorder|Atypical Anorexia Nervosa
Interventions: DRUG: Denosumab 60 MG [Prolia]|DRUG: Placebo Injection|DRUG: Alendronate 70Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Index - Variability Among Individuals
Status: COMPLETED
Conditions: Diabetes|Obesity|Metabolic Syndrome|Cardiovascular Disease
Interventions: OTHER: Carbohydrate + Protein|OTHER: Carbohydrate + Fat|OTHER: Fiber|OTHER: Carbohydrate load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bevacizumab Combined With Fractionated Stereotactic Radiotherapy for 1 to 10 Brain Metastases From NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: COMBINATION_PRODUCT: FSRT combined with Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
Status: RECRUITING
Conditions: Essential Thrombocythemia
Interventions: DRUG: Bomedemstat|DRUG: Hydroxyurea|DRUG: Bomedemstat placebo|DRUG: Hydroxyurea placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of rFXIII in Patients Following First Time Myocardial Revascularization Requiring Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Cardiac Surgery Requiring Cardiopulmonary Bypass
Interventions: DRUG: catridecacog|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult T-cell Leukemia-Lymphoma|ATLL
Interventions: DRUG: Belinostat|DRUG: Zidovudine|DRUG: Interferon-Alfa-2b|DRUG: Pegylated Interferon-Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bile Acids on the Secretion of Satiation Peptides in Humans
Status: COMPLETED
Conditions: Echolocation
Interventions: OTHER: saline|OTHER: bile acid (CDCA, chenodeoxycholic acid)|OTHER: oleanolic acid|DIETARY_SUPPLEMENT: oleic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Proof-of-concept (PoC) Study of APD515
Status: COMPLETED
Conditions: Xerostomia in Advanced Cancer Patients
Interventions: DRUG: APD515|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Relative Bioavailability Study With Rabeprazole Sodium in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: rabeprazole sodium|DRUG: rabeprazole sodium|DRUG: rabeprazole sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Messages About Reduced Nicotine in Combusted Tobacco Products
Status: COMPLETED
Conditions: Health Communication|Smoking|Smoking, Tobacco|Smoking Behaviors|Risk Behavior
Interventions: BEHAVIORAL: Reduced nicotine message exposure|BEHAVIORAL: Modified risk message exposure|BEHAVIORAL: Combined message exposure (reduced nicotine + modified risk)|BEHAVIORAL: Control message exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for the Prevention of Chemotherapy Induced Nausea and Vomiting
Status: UNKNOWN
Conditions: Nausea
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Atazanavir (ATV) 150L Mutation on Subsequent Treatment Response in HIV Infected Subjects
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: LPV/RTV + 2NRTIs|DRUG: LPV/RTV + 2NRTIs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LEV102 Topical Gel in Acquired Blepharoptosis
Status: COMPLETED
Conditions: Acquired Blepharoptosis
Interventions: DRUG: LEV102 1.0%|DRUG: LEV102 2.0%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Increased Muscular Work During Different Weaning Strategies in Critically Ill Patients
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: BIPAP|DEVICE: PSV|DEVICE: PSV + CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: Netarsudil ophthalmic solution 0.02%|OTHER: Netarsudil Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices
Status: UNKNOWN
Conditions: Esophageal and Gastric Varices|Ulcer|Cirrhosis|Hypertension, Portal
Interventions: DEVICE: Esophagogastroduodenoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety Study of ABP 980 Compared With Trastuzumab in Women With HER2-positive Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: ABP 980|DRUG: Trastuzumab|DRUG: Paclitaxel|PROCEDURE: Lumpectomy or Mastectomy with Sentinel Node or Axillary Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRISM (Panitumumab Regimen In Second-line Monotherapy of Head and Neck Cancer)
Status: COMPLETED
Conditions: Cancer|Carcinoma|Head and Neck Cancer|Metastases|Metastatic Cancer|Metastatic or Recurrent Squamous Cell Carcinoma of Head and Neck|Oncology|Squamous Cell Carcinoma|Tumors
Interventions: DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of KQ-2003 CAR-T Cell Therapy for Patients With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: KQ-2003 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia
Status: UNKNOWN
Conditions: Alzheimer's Disease|Progressive Primary Aphasia|Early or Mild State
Interventions: DEVICE: transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Evaluation of Diclofenac Sodium Transdermal Patch, Oral Diclofenac Sodium With Intramuscular Injections of Diclofenac Sodium in Patients Suffering From Oral Pain
Status: COMPLETED
Conditions: Orofacial Pain
Interventions: DRUG: Diclofenac Sodium|DRUG: Diclofenac sodium|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pulmonary Safety of Staccato Alprazolam in Healthy Study Participants and in Study Participants With Mild Asthma
Status: COMPLETED
Conditions: Healthy Study Participants|Participants With Mild Asthma
Interventions: DRUG: Alprazolam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of HIIT Vs Moderate Intensity Aerobic Exercise on Insulin Resistance in Type 2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus|Insulin Resistance
Interventions: OTHER: High intensity interval training|OTHER: moderate intensity aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HELP-HY: Health Education and sLeep Program in HYpertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Prehypertension|Hypertension
Interventions: BEHAVIORAL: Sleep Enhancement|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Revascularization for Radiation Induced Carotid Artery Stenosis
Status: RECRUITING
Conditions: Radiation-induced Carotid Artery Stenosis
Interventions: PROCEDURE: Carotid endarterectomy (CEA)|PROCEDURE: Carotid artery stenting (CAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine
Status: COMPLETED
Conditions: Pain|Pharmacokinetics|Flupirtine
Interventions: DRUG: 100 mg flupirtine intravenous|DRUG: 100 mg flupirtine per os|DRUG: 400 mg flupirtine per os|PROCEDURE: induce delayed onset of muscle soreness (DOMS)|PROCEDURE: electric pain measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Computer-Based System for Symptom Reporting in Patients With Cancer Undergoing Treatment
Status: COMPLETED
Conditions: Caregiver|Malignant Neoplasm
Interventions: OTHER: Best Practice|OTHER: Computer Application|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH