pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of the ECHOs Approach for Patients With Eating Disorders and Their Carers
Status: COMPLETED
Conditions: Eating Disorders
Interventions: BEHAVIORAL: ECHOs plus TAU|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Cell-Assisted Lipotransfer for the Treatment of Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Periurethral injection of fat micrograft enriched with ADRC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Administration on N-Acetylcysteine on Serum Creatinine Levels in Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine (Egg-Derived) in Healthy Subjects From 6 Months to 17 Years of Age
Status: COMPLETED
Conditions: Pandemic Influenza
Interventions: BIOLOGICAL: Monovalent A/H1N1 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: vNEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Randomized, Double-Blind, Placebo-Controlled, Clinical Trial to Compare the Safety and Immunogenicity of Recombinant Envelope Protein rgp120/HIV-1SF2 (BIOCINE) Combined With Seven Adjuvants in Healthy HIV-1 Uninfected Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Aluminum hydroxide|BIOLOGICAL: Lipid A, Monophosphoryl|BIOLOGICAL: Lipid A, Liposome-encapsulated monophosphoryl|BIOLOGICAL: Syntex adjuvant formulation|BIOLOGICAL: MF59|BIOLOGICAL: Threonyl Muramyl Dipeptide|BIOLOGICAL: rgp120/HIV-1 SF-2|BIOLOGICAL: MTP-PE/MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Dose-Finding Study of GSK2894512 Cream in Subjects With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: GSK2894512 1% Cream|DRUG: GSK2894512 0.5% Cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: RM-131|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate The Effect Of Ketoconazole, Ritonavir and Erythromycin on the Safety and Pharmacokinetics of Avanafil
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Ritonavir|DRUG: Ketoconazole|DRUG: Erythomycin|DRUG: Avanafil|DRUG: Avanafil|DRUG: Avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Level Daytime Sleepiness: Social-Environmental Determinants, Consequences, and Impact of Sleep Apnea
Status: COMPLETED
Conditions: Daytime Sleepiness
Interventions: BEHAVIORAL: Track 1|BEHAVIORAL: Track 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO)
Status: RECRUITING
Conditions: ATTR Amyloidosis|Cardiopathy|Carpal Tunnel Syndrome|Lumbar Spine Stenosis|Hip Prosthesis|Knee Prosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trametinib in Treating Patients With Progressive Metastatic Hormone-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 5μg/ml ESAT6-CFP10 in left arm and TB-PPD in right arm|BIOLOGICAL: 5μg/ml ESAT6-CFP10 in right arm and TB-PPD in left arm|BIOLOGICAL: 10μg/ml ESAT6-CFP10 in left arm and TB-PPD in right arm|BIOLOGICAL: 10μg/ml ESAT6-CFP10 in right arm and TB-PPD in left arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess LX201 for Prevention of Corneal Allograft Rejection or Graft Failure in Subjects Who Have Experienced One or More Rejection Episodes Following Penetrating Keratoplasty
Status: TERMINATED
Conditions: Corneal Transplantation|Corneal Graft Rejection
Interventions: DRUG: LX201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®)
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: DEVICE: HFNC|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of tACS Combined With CCT for Patients With MCI
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial Alternating Current Stimulation|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of a Novel HSP90 Inhibitor (CUDC-305) in the Treatment of Moderate to Severe Psoriasis.
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: CUDC-305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine
Status: COMPLETED
Conditions: Pulmonary Aspiration of Gastric Contents|Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics|Pulmonary Aspiration During Anaesthetic Induction
Interventions: DIETARY_SUPPLEMENT: Maltodextrin|DIETARY_SUPPLEMENT: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation
Status: UNKNOWN
Conditions: Renal Impairment|Liver Transplantation|Everolimus
Interventions: DRUG: delayed, low-dose CNI|DRUG: BU-CNI|DRUG: BU-Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Continuation of Original Targeted Therapy With Trastuzumab Combined With Pyrotinib and Capecitabine as Postoperative Adjuvant Therapy in Non-pCR Patients With HER2 Positive Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Adjuvant Therapy
Interventions: DRUG: Pyrotinib+Trastuzumab+Capecitabine|DRUG: Trastuzumab+Pertuzumab/Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide, Vorinostat and Dexamethasone in Relapsed Patients With Peripheral T-Cell Non-Hodgkin's Lymphoma (PTCL)
Status: TERMINATED
Conditions: Peripheral T-Cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Vorinostat, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM
Status: RECRUITING
Conditions: Severe Acute Malnutrition|HIV|Comorbidities and Coexisting Conditions|Child Malnutrition
Interventions: DRUG: Rifampicin|DRUG: Azithromycin|DRUG: Isoniazid|DRUG: Pyridoxine Hydrochloride|BEHAVIORAL: The Friendship Bench|BEHAVIORAL: Care for Child Development|BEHAVIORAL: Educational and behaviour-change modules|DIETARY_SUPPLEMENT: Reformulated Ready to Use Therapeutic Food|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Treatment as the Neoadjuvant Therapy in Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Neoadjuvant Therapy
Interventions: DRUG: FOLFOX regimen|DRUG: apatinib and FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Capecitabine Plus Oxaliplatin (XELOX) and Capecitabine (X) as First-line Chemotherapy in Elderly Patients With Advanced Gastric Cancer
Status: WITHDRAWN
Conditions: Gastric Cancer
Interventions: DRUG: XELOX|DRUG: XELODA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer
Status: COMPLETED
Conditions: Dysphagia|Pain|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Dexamethasone|DRUG: Dexamethasone|OTHER: Placebo|PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Transoral Robotic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Operative Nausea and Vomiting|Breast Cancer
Interventions: PROCEDURE: Electrical Stimulation|DRUG: Zofran|DRUG: Dexamethasone|DRUG: Phenergan|DRUG: Pepcid|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Open Label Trial to Assess Safety of BIBW 2992 (Afatinib) in Combination With Herceptin® in Patients With HER2-positive Advanced Breast Cancer.
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Trastuzumab|DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscope Combined Ureteroscopic Air-pressure Ballistic Lithotripsy to Treat Patients With Hepatolithiasis
Status: UNKNOWN
Conditions: Cholelithiasis
Interventions: PROCEDURE: ureteroscopic air-pressure ballistic lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Relative Effectiveness of Two Front-of-pack Nutrition Labels
Status: COMPLETED
Conditions: Diet Habit|Diet Modification|Food Selection|Food Preferences|Nutrition Poor
Interventions: BEHAVIORAL: Multiple Traffic Light Label|BEHAVIORAL: Nutri-Score Label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction
Status: RECRUITING
Conditions: Breast Cancer|Heart Failure
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rest-exercise Transition Training to Improve Cardiac Vagal Tone
Status: COMPLETED
Conditions: Subjects Evaluated With Low Cardiac Vagal Tone
Interventions: OTHER: Supervised exercise program|OTHER: Supervised exercise program together with a specific sudden rest-exercise training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder
Status: RECRUITING
Conditions: Panic Disorder
Interventions: DRUG: Darigabat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Duration of Popliteal Block Versus Ankle Block in Patients Undergoing Forefoot Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Ankle Block|PROCEDURE: Sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tamoxifen in Treating Women With High-Risk Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|DRUG: tamoxifen citrate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
Status: COMPLETED
Conditions: Airway Complication of Anesthesia
Interventions: DRUG: propofol|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: DEVICE: Micropulse Laser Trabeculoplasty|DEVICE: Selective Laser Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate
Status: RECRUITING
Conditions: AFF With RVR|Atrial Fibrillation With Rapid Ventricular Response (Disorder)|Hypotension Drug-Induced
Interventions: DRUG: Calcium pre-treatment|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: External Versus Internal Feedback in Patients With Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Injuries|Ankle Inversion Sprain
Interventions: OTHER: External focus of attention visual feedback|OTHER: External focus of attention auditory feedback|OTHER: Internal focus of attention video feedback|OTHER: No feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Surgical Sutent in Renal Cell Carcinoma (RCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|PROCEDURE: Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-operator Wire-guided Endoscopic Retrograde Cholangiopancreatography Cannulation Technique
Status: COMPLETED
Conditions: Biliary Diseases|Pancreas Diseases
Interventions: PROCEDURE: Team 1|PROCEDURE: Team 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer
Status: RECRUITING
Conditions: Oligometastatic Prostate Cancer
Interventions: DRUG: Quemliclustat|DRUG: Etrumadenant|DRUG: Zimberelimab|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Regular Consumption of Eggs and Nutrients Fortified Eggs on Eczema Condition in Singapore Individuals
Status: RECRUITING
Conditions: Atopic Dermatitis Eczema|Aging|Diet Modification
Interventions: DIETARY_SUPPLEMENT: Nutrient-fortified egg|DIETARY_SUPPLEMENT: Regular egg with habitual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Selected Aerosol Constituents Levels in the Exhaled Breath of Adult e-Vapor Users
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: e-Vapor Product A|OTHER: e-Vapor Product B|OTHER: e-Vapor Product C|OTHER: e-Vapor Product D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Protein Supplementation and HIIT: Impact on Cardiorespiratory Fitness
Status: UNKNOWN
Conditions: Primary Prevention|Health Promotion
Interventions: DIETARY_SUPPLEMENT: HIIT + protein|DIETARY_SUPPLEMENT: HIIT + placebo|DIETARY_SUPPLEMENT: HIIT and resistance training + protein|DIETARY_SUPPLEMENT: HIIT and resistance training + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study
Status: COMPLETED
Conditions: Influenza|Pneumonia, Viral|Pulmonary Fibrosis|Quality of Life|Stress Disorders, Post Traumatic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SR-Exenatide (PT320) to Eveluate Efficacy and Safety in Patients With Early Parkinson's Disease
Status: UNKNOWN
Conditions: Early Parkinson's Disease
Interventions: DRUG: PT320 2.0mg Placebo|DRUG: PT320 2.0 mg|DRUG: PT320 2.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cast Immobilization Versus Percutaneous Pinning for Fracture of Radius in an Elderly Patient
Status: COMPLETED
Conditions: Closed Fracture of Lower End of Radius
Interventions: PROCEDURE: Percutaneous pinning|PROCEDURE: Cast immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
Status: RECRUITING
Conditions: Orthodontic Appliance Complication|Plaque, Dental|Gingival Inflammation
Interventions: DEVICE: Lumoral Treatment|OTHER: Standard oral health instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Facial Cutaneous Squamous Cell Carcinoma in Situ
Interventions: COMBINATION_PRODUCT: Aminolevulinic Acid 20% Topical Solution with Blue Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decline in Renal Concentration Ability in Lithium Treated Patients
Status: UNKNOWN
Conditions: Lithium Toxicities|Bipolar Disorder|Concentration Ability Impaired|Nephrogenic Diabetes Insipidus|Lithium - Induced Nephropathy
Interventions: DIAGNOSTIC_TEST: Deamino Arginine Vasopressin (dDAVP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Assessment of Chinese Herbal Medicine Tangweian Recipe Treating Participants With Diabetic Gastroenteropathy
Status: NOT_YET_RECRUITING
Conditions: Diabetic Gastroenteropathy
Interventions: DRUG: Tangweian Recipe|DRUG: Mosapride Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Venous Thromboses|Heavy Menstrual Bleeding|Anticoagulants and Bleeding Disorders
Interventions: DRUG: Tranexamic acid|OTHER: No Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diet Improvement Through Normative Experimentation
Status: COMPLETED
Conditions: Diet Quality
Interventions: BEHAVIORAL: Norm-based messaging and peer comparison features|BEHAVIORAL: Financial Incentives leveraging on loss aversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 1 to Evaluate the Safety and Pharmacokinetic Durg-drug Interaction of YYC506-T and YYC506-A
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: YYC506-T|DRUG: YYC506-A|DRUG: YYC506-T + YYC506-A|DRUG: YYC506-A + YYC506-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Dose Study to Assess Blood and Urine Drug Levels of Fostamatinib in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Japanese Volunteers
Interventions: DRUG: Fostamatinib 100mg|DRUG: Fostamatinib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of a Mindful Parenting Intervention for Parents of Children With Psoriasis and Parents of Children With Eczema
Status: COMPLETED
Conditions: Psoriasis|Eczema|Stress
Interventions: BEHAVIORAL: Mindful Parenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proteomic Profiling in Diagnosing Ovarian Cancer in Patients Who Are Undergoing Surgery for an Abnormal Pelvic Mass
Status: UNKNOWN
Conditions: Fallopian Tube Cancer|Ovarian Cancer
Interventions: GENETIC: proteomic profiling|OTHER: surface-enhanced laser desorption/ionization-time of flight mass spectrometry|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Cold Snare Versus Double Biopsy Polypectomy Technique for Removal of Diminutive Colorectal Polyps
Status: COMPLETED
Conditions: Polyp of Large Intestine
Interventions: PROCEDURE: removal of eligible polyps using cold snare polypectomy technique|PROCEDURE: removal of eligible polyps using double biopsy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy Expenditure
Status: COMPLETED
Conditions: Hyperthyroidism
Interventions: DRUG: carbimazole (CMZ) or thiamazole (TMZ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Restriction Pressure on Muscle Damage Responses to Blood Flow Restriction Exercise
Status: COMPLETED
Conditions: Muscle Damage|Muscle Soreness|Muscle Strength
Interventions: OTHER: Blood flow restriction at 40% limb occlusion pressure|OTHER: Blood flow restriction at 80% limb occlusion pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Stress Urinary Incontinence|Satisfaction
Interventions: OTHER: Online risk calculator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Activity and Social Engagement for Persons With Disabilities in an Underserved Community
Status: ACTIVE_NOT_RECRUITING
Conditions: Disability Physical|Chronic Conditions, Multiple|Aging
Interventions: BEHAVIORAL: Lakeshore Online Fitness (Online)|BEHAVIORAL: Get Active with Virtual Reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Peripheral Nociceptive Effects of Levcromakalim
Status: COMPLETED
Conditions: Pain|Levcromakalim
Interventions: DRUG: Levcromakalim|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: oral rehydration solution Hipp ORS Apple 200|DIETARY_SUPPLEMENT: ESPGHAN ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neural Glides Versus Proprioceptive Neuromuscular Facilitation in Cervical Radiculopathy
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Neural Glide|OTHER: Rhythmic stabilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: C-Pulse Implantable Counterpulsation Pump (ICP) - A Heart Assist Device
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: C-Pulse™ (Implantable Counterpulsation Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers
Status: RECRUITING
Conditions: Cervical Carcinoma|Fallopian Tube Carcinoma|Malignant Solid Neoplasm|Malignant Uterine Neoplasm|Ovarian Carcinoma|Primary Peritoneal Carcinoma|Vulvar Carcinoma
Interventions: OTHER: Best Practice|DRUG: Cilostazol|DEVICE: Cryocompression Therapy|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention Through Intervention: Telehealth Solution to Deter 911 Calls Due to Hypoglycemia
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypoglycemia Unawareness|Hypoglycemia|Hypoglycemia Acute
Interventions: BEHAVIORAL: Hypoglycemia Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: AML/MDS
Interventions: DRUG: Decitabine|DRUG: Midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy
Status: RECRUITING
Conditions: Neonatal Seizure|Hypoxic-Ischemic Encephalopathy|Stroke|Intracranial Hemorrhage|Epilepsy|Gene Abnormality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Fluticasone-salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Advair 250|DRUG: Placebo- matched|DRUG: Placebo|DRUG: Advair 250 - matched
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Airtime Amounts to Improve Interactive Voice Response Surveys in Colombia and Tanzania
Status: COMPLETED
Conditions: Surveys and Questionnaires|Noncommunicable Diseases
Interventions: OTHER: 1X airtime incentive|OTHER: 2X airtime incentive|OTHER: Lottery airtime incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Midostaurin Access Program for Newly Diagnosed FLT3 (ITD or TKD) Mutated AML Adult Patients Eligible for Standard Induction and Consolidation Chemotherapy
Status: NO_LONGER_AVAILABLE
Conditions: Acute Myeloid Leukemia (AML) With|FLT3 Mutation, Internal Tandem Duplication (ITD) or Tyrosine Kinase Domain (TKD)
Interventions: DRUG: Midostaurin
Study Type: EXPANDED_ACCESS
Clinical trial: MRI in Predicting Early Response to Chemotherapy in Patients With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: systemic chemotherapy|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing Gum
Status: COMPLETED
Conditions: Esophagitis|Gastro Oesophageal Reflux Disease
Interventions: DEVICE: Calcite chewing gum|DEVICE: Unmatched Placebo chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn
Status: COMPLETED
Conditions: Persistent Pulmonary Hypertension of the Newborn
Interventions: OTHER: Ages & Stages Questionnaires®, Third Edition (ASQ3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neurodevelopmental Outcome of Early Dietary Lysine Restriction in Pyridoxine Dependent Epilepsy Patients
Status: WITHDRAWN
Conditions: Pyridoxine Dependant Epilepsy
Interventions: DIETARY_SUPPLEMENT: Lysine Restricted Diet|DRUG: Pyridoxine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Besivance™ for Treatment of Congenital Nasolacrimal Duct Obstruction in Children
Status: COMPLETED
Conditions: Congenital Nasolacrimal Duct Obstruction
Interventions: DRUG: Besivance Treatment Group|DRUG: Polytrim Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Topical TolaSure Targeting Aggregated Mutant Keratin in Severe Epidermolysis Bullosa Simplex
Status: COMPLETED
Conditions: Epidermolysis Bullosa Simplex
Interventions: DRUG: TolaSure Topical Gel|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic-guided TAP Block in Patients Undergoing Gastric Bypass
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Metamizol iv|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Stage IA Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pioglitazone Hydrochloride|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Neurofunctional Responses to Breakfasts
Status: COMPLETED
Conditions: Feeding Behaviors|Lack of Satiety|Attention Deficit and Disruptive Behavior Disorders
Interventions: DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Milk & Cereals|DIETARY_SUPPLEMENT: Milk, apple & snack|DIETARY_SUPPLEMENT: Milk, apple & bread w/ cream|DEVICE: EEG_pre|DEVICE: EEG_post
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of VPro5 Therapy on Clear Aligner Therapy
Status: COMPLETED
Conditions: Malocclusion
Interventions: DEVICE: VPro5 device|OTHER: Deviation from Standard Tray Wear Time (14 Days)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients
Status: COMPLETED
Conditions: Alzheimer Disease|Sleep Apnea, Obstructive
Interventions: DRUG: donepezil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of R3421 in Patients With Moderate to Severe Chronic Plaque Psoriasis.
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: RG3421 120mg|DRUG: RG3421 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Sinus Lift Through the Interradicular Septum
Status: RECRUITING
Conditions: Bone Loss|Bone Loss, Age-related|Atrophy; Alveolar Process|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Interradicular septum window
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Toolbox for Healthcare Providers in Mexico
Status: ACTIVE_NOT_RECRUITING
Conditions: Distress, Emotional|Burnout, Professional|Inflammation|Emotion Regulation
Interventions: BEHAVIORAL: Integrated Stress Toolbox for Healthcare Providers (ISTH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of a School Disinfection and Hand Hygiene Program
Status: COMPLETED
Conditions: Respiratory Infections|Gastrointestinal Diseases
Interventions: OTHER: Alcohol-based hand sanitizer & quaternary ammonium wipes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Pharmacokinetic Characteristics and Safety of Dilatrend SR Capsule 32mg and Dilatrend Tablet 25mg
Status: UNKNOWN
Conditions: Essential Hypertension|Chronic Stable Angina|Congestive Heart Failure
Interventions: DRUG: Dilatrend SR capsule 32mg|DRUG: Dilatrend IR tablet 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Recombinant Human Growth Hormone (rhGH) on the Myopathy of Cystinosis
Status: WITHDRAWN
Conditions: Cystinosis|Myopathy
Interventions: DRUG: rh Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Low Dose Hypertonic Saline Solution and High Dose Furosemide for Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Renal Insufficiency
Interventions: DRUG: furosemide and hypertonic saline solution|DRUG: furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Differentiated Models of Antiretroviral Treatment (ART) Provision
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: OTHER: Three monthly ART supply at CAGs|OTHER: Six monthly ART supply at outreaches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Study of a Once Daily Antiretroviral Regimen in Vietnam (ANRS 1210 VIETAR)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: efavirenz|DRUG: didanosine|DRUG: lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Study to Investigate the Efficacy, and Safety of the Colovac Colorectal Anastomosis Protection Device.
Status: COMPLETED
Conditions: Gastrointestinal Anastomotic Complication
Interventions: DEVICE: COLOVAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Assisted Fluid Management IDE Study
Status: COMPLETED
Conditions: Non-Cardiac/ Non-Thoracic Surgery|Abdominal Surgery|Pelvic Surgery|Major Peripheral Vascular Surgery
Interventions: DEVICE: EV1000 Clinical Platform with Assisted Fluid Management (AFM) Feature
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer, Small Cell|Lung Cancer Metastatic|Lung Cancer Recurrent|Treatment Side Effects|Lung Cancer, Non-small Cell|Nutritional Imbalance
Interventions: BEHAVIORAL: Nutritional Counseling|OTHER: Medically Tailored Meals (MTMs)|BEHAVIORAL: Nutrition Prescription|OTHER: Nutrition Assessment|BEHAVIORAL: Nutrition Toolkit|BEHAVIORAL: Monthly Emails
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Made to Measure Compression Garments for Recovery in Rugby Players
Status: COMPLETED
Conditions: Muscle Damage
Interventions: DEVICE: Custom fitted compression garments (CF)|DEVICE: Standard-sized compression garments (SSG)|PROCEDURE: Sham ultrasound (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of Autologous Non-Hematopoietic Peripheral Blood Stem Cells in COVID-19
Status: COMPLETED
Conditions: Coronavirus Disease 2019 (COVID-19)
Interventions: BIOLOGICAL: Autologous Non-Hematopoietic Peripheral Blood Stem Cells (NHPBSC)|DRUG: COVID-19 standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)
Status: COMPLETED
Conditions: Hepatitis C|HIV Coinfection
Interventions: DRUG: TDF with a boosted protease inhibitor|DRUG: TAF with a boosted protease inhibitor|DRUG: TAF with a boosted protease inhibitor and LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Safety of In-bed Cycling/Stepping in Critically Ill Patients
Status: RECRUITING
Conditions: Critically Ill Patient|Intensive Care Unit Acquired Weakness
Interventions: DEVICE: Conventional rehabilitation plus multimodal exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Surgery and ART For Endometrioma
Status: NOT_YET_RECRUITING
Conditions: Ovarian Endometrioma|Infertility, Female
Interventions: PROCEDURE: Laparoscopic enucleation of ovarian endometrioma.|PROCEDURE: Prolonged pituitary downregulation|PROCEDURE: Assisted Reproductive Technology (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InterSEPT: In-Tunnel SeptRx European PFO Trial
Status: UNKNOWN
Conditions: Foramen Ovale, Patent|Heart Defects, Congenital|Heart Septal Defects
Interventions: DEVICE: Transcatheter PFO closure with the SeptRx Intrapocket PFO Occluder (IPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Tropisetron Plus Risperidone for Improving Cognitive and Perceptual Disturbances in Schizophrenia
Status: COMPLETED
Conditions: Smoking Cessation|Schizophrenia
Interventions: DRUG: Tropisetron|DRUG: Placebo|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348
Status: COMPLETED
Conditions: Hypertension and Dyslipidemia
Interventions: DRUG: CKD-348|DRUG: CKD-828, D097, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U/s Guided Oblique Subcostal Transversus Abdominis Plane Block Versus Erector Spinae Plane Block as Preemptive Analgesia
Status: COMPLETED
Conditions: Pain|Hernia, Umbilical
Interventions: DRUG: Bupivacain|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FINNPROSTATE Study VII: Intermittent Versus Continuous Androgen Deprivation in Patients With Advanced Prostate Cancer
Status: UNKNOWN
Conditions: Patients With T1-4 Advanced Prostate Cancer
Interventions: DRUG: Goserelin (Zoladex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Fatigue and Carbonic Anhydrase Inhibitors
Status: COMPLETED
Conditions: Hypoxia
Interventions: DRUG: Acetazolamide|DRUG: Methazolamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-hour Application
Status: WITHDRAWN
Conditions: Conjunctical Flora
Interventions: DRUG: gatifloxacin, moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Range of Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Otherwise Healthy Smokers
Status: TERMINATED
Conditions: Healthy Smokers
Interventions: BIOLOGICAL: CCRE inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bupropion and Weight Control for Smoking Cessation - 1
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Bupropion|DRUG: Placebo|BEHAVIORAL: weight concerns intervention|BEHAVIORAL: smoking cessation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetics of Two Different Oral Delivery Systems of Cholecalciferol
Status: UNKNOWN
Conditions: Vitamin D Deficiency
Interventions: DRUG: SunnyD insta ampoule|DIETARY_SUPPLEMENT: SunnyD STAT softgel capsule|DRUG: Placebo SunnyD insta ampoule|DIETARY_SUPPLEMENT: Placebo SunnyD STAT softgel capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 to 85 Years, Who Will Each Receive 3 Doses Of Vaccine.
Status: COMPLETED
Conditions: Clostridium Difficile Associated Disease
Interventions: BIOLOGICAL: Clostridium difficile vaccine|BIOLOGICAL: Clostridium difficile vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance
Status: COMPLETED
Conditions: Solid Tumors|Advanced Cancer
Interventions: DRUG: Anastrozole|DRUG: Bevacizumab|DRUG: Everolimus|DRUG: Sorafenib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Biomicroscopy - Apoptosis
Status: COMPLETED
Conditions: Lymphoma|Lymphoma, Non-Hodgkin|Melanoma|Carcinoma, Basal Cell
Interventions: PROCEDURE: high frequency ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC