pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Chemoprotective Activity of MMV390048 in PfSPZ Challenge Model
Status: WITHDRAWN
Conditions: Malaria,Falciparum
Interventions: DRUG: MMV390048
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis
Status: COMPLETED
Conditions: Pancreatic Carcinoma Metastatic|Pancreatic Adenocarcinoma|Pancreatic Neoplasms|Pancreatic Cancer|Pancreatic Cancer, Adult
Interventions: OTHER: Celiac Plexus Neurolysis|OTHER: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Vapocoolant|DEVICE: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Japan Phase 2 Study of Niraparib (Maintenance Therapy) in Participants With Relapsed Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Evaluating XSTAT Use in the Prehospital Setting
Status: TERMINATED
Conditions: Shock, Hemorrhagic|Injury Penetrating|Hemorrhage
Interventions: DEVICE: XSTAT|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Enavogliflozin in Heart Failure With Preserved Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure, Preserved Ejection Fraction
Interventions: DRUG: SGLT2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: PF-04171327 10 mg|OTHER: Prednisone Placebo|DRUG: PF-04171327 25 mg|OTHER: Prednisone Placebo|DRUG: Prednisone 5 mg|OTHER: Placebo for PF-04171327|OTHER: Placebo|OTHER: Placebo for PF-04171327
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of ID119031166M With the Exploration of Pharmacodynamic Effects
Status: TERMINATED
Conditions: Healthy Participants
Interventions: DRUG: ID119031166M|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Delayed Loading of Maxillary Overdenture Implants
Status: RECRUITING
Conditions: Implant Complication
Interventions: PROCEDURE: Immediate loading of maxillary implant overdenture|PROCEDURE: Delayed loading of maxillary implant overdenture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atomoxetine in the Prevention of Vasovagal Syncope
Status: RECRUITING
Conditions: Vasovagal Syncope
Interventions: DRUG: Atomoxetine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Driving Risk Factors in Type 1 Diabetes and Their Reduction Via Internet Program (DiabetesDriving.Com)
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: BEHAVIORAL: DD.com|BEHAVIORAL: DD.com + MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A to Treat Flexion Contracture After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Flexion Contracture Following Total Knee Replacement
Interventions: DRUG: Botox|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cancer Patients' Preferences for Genetic Information Modalities Preceding Theranostic Exome Analysis.
Status: NOT_YET_RECRUITING
Conditions: All Types of Metastatic Solid Malignancy|1st-line Treatment|Exome Analysis|Active File EXOMA2 Study
Interventions: OTHER: Cancer patients' preferences regarding genetic information modalities prior to theranostic exome analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-Label Extension Trial to Assess the Safety and Tolerability of Long Term Treatment of Rotigotine in Subjects With Idiopathic Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Intravenous Nafithromycin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nafithromycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 802NP302 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia
Status: WITHDRAWN
Conditions: Trigeminal Neuralgia
Interventions: DRUG: BIIB074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methods That Reduce Pain During Debonding Fixed Orthodontic Appliance
Status: RECRUITING
Conditions: Pain
Interventions: DEVICE: SureSmile® VPro™|OTHER: ortho technology, sports advantage, thermal forming soft EVA 3mm|OTHER: cotton roll
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tissue Level vs Bone Level Implants for Plural Restorations : a Multicentre Randomised Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implants|Edentulous
Interventions: DEVICE: Axiom TL REG|DEVICE: Axiom BL REG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neuromobılızatıon on Stiffness of Scıatıc Nerve
Status: UNKNOWN
Conditions: Neuromobılızatıon|Stiffness|Scıatıc Nerve|Nonspecific Low Back Pain
Interventions: OTHER: Sciatic nerve neuromobilization techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Right Lower Limb Orthopedic Immobilization on Braking Function
Status: COMPLETED
Conditions: Automobile Driving With an Aircast Walker|Automobile Driving With a Walking Cast
Interventions: PROCEDURE: Driving with an Aircast Walker|PROCEDURE: Driving with a walking cast|PROCEDURE: Driving with a running shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring
Status: TERMINATED
Conditions: Traumatic Brain Injury|Intracranial Hypertension
Interventions: DRUG: variation of mannitol dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemoradiotherapy in Unresectable Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer|Chemoradiotherapy|Albumin-bound Paxlitaxel|Unresectable Malignant Neoplasm
Interventions: RADIATION: Radiotherapy|DRUG: Albumin-Bound Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Blinded Study Evaluating the Accuracy and Safety of Cyclotron-produced 99mTc in Adult Patients
Status: COMPLETED
Conditions: Hyperthyroidism
Interventions: DRUG: Cyclotron-produced 99mTc|DRUG: Generator-produced 99mTc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Spectral Photon Counting CT (SPCCT) With Dual Energy CT (DECT) and Magnetic Resonance Imaging (MRI) for Plaque and Lumen Carotid Arteries Evaluation
Status: COMPLETED
Conditions: Supra-Aortic Stenosis
Interventions: DIAGNOSTIC_TEST: Spectral Photon Counting Computed Tomography (SPCCT)|DIAGNOSTIC_TEST: Dual Energy CT (DECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Socket Preservation Using Socket Shield Technique Comparison of Socket Preservation Using Socket Shield Technique With Autogenous Dentin Graft Versus Alloplast Graft Material
Status: COMPLETED
Conditions: Extraction Tooth Socket
Interventions: PROCEDURE: Modified socket shield technique with autogenous dentin graft material (in one side)|PROCEDURE: Modified socket shield technique with alloplast graft material (in contralateral side)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Liposomal bupivacaine|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 2b Study of ALTO-100 in MDD
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: ALTO-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: Pembrolizumab|RADIATION: External beam radiation|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Treatment for Chronic Hepatitis C With Normal Transaminases in HIV Positive Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a + ribavirin in normal ALT|DRUG: Peginterferon alfa-2a + ribavirin in elevated ALT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of 3-dimensional Printed Implant Cast Versus Conventional Stone Cast for Edentulous Mandibular Arch
Status: ENROLLING_BY_INVITATION
Conditions: Prosthesis Durability
Interventions: PROCEDURE: implant casts fabrication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Image-guided Thermal Ablation vs. Lobectomy for Solitary Papillary Thyroid Microcarcinoma
Status: COMPLETED
Conditions: Papillary Thyroid Cancer
Interventions: PROCEDURE: thyroid lobectomy|PROCEDURE: image-guided thermal ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control
Status: COMPLETED
Conditions: Urolithiasis|Kidney Stones
Interventions: PROCEDURE: Technologist control of fluoroscopy|PROCEDURE: Surgeon control of fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Implant Thread Design on Implant Stability Quotient (ISQ) in Early Healing Period
Status: COMPLETED
Conditions: Partial Edentulism
Interventions: DEVICE: Megagen AnyRidge dental implant|DEVICE: Megagen EZ Plus dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center Study to Examine Changes to the Environment Surrounding the Electrodes in the Cochlea and to Capture the Most Challenging Listening Environments Experienced by Persons With a Cochlear Implant
Status: ACTIVE_NOT_RECRUITING
Conditions: Hearing Loss
Interventions: DEVICE: The impedance measurement task using the Mobile Research App (MRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Trial of Flumazenil for the Treatment of Obsessive Compulsive Disorder
Status: TERMINATED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Flumazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obese Hypertension Study (0954-315)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Comparator: losartan +/- HCTZ|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can a Relaxometer Improve Cognitive Impairment of Fibromyalgia Patients
Status: UNKNOWN
Conditions: Fibromyalgia Syndrome|Fibromyalgia|Pain, Chronic|Impairment|Cognitive Impairment
Interventions: OTHER: Relaxometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of SGN-MesoC2 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Ovarian Neoplasms|Pancreatic Adenocarcinoma|Colorectal Neoplasms|Mesothelioma|Other Solid Tumors
Interventions: DRUG: SGN-MesoC2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: BIOLOGICAL: empegfilrastim|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Study to Evaluate BMS-986165 in Participants With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: BMS-986165|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures
Interventions: DRUG: PENG block and cryoablation|DRUG: fascia iliaca compartment block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of PBK_L2201 in Postmenopausal Women With Osteoporosis
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: PBK_L2201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Relapsed or Progressive Systemic Mastocytosis
Status: COMPLETED
Conditions: Non Neoplastic Condition|Precancerous Condition
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate P-Glucose, Safety and Tolerability After Oral Single Dosing of AZD6370 in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD6370|DRUG: AZD6370|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation.
Status: NOT_YET_RECRUITING
Conditions: Femur Fracture
Interventions: PROCEDURE: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study to Evaluate the Efficacy of Fluvastatin on Inflammatory Markers in Patients With Aortic Stenosis.
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Safety of Local Cryotherapy Treatment of Recurrent Head and Neck Cancer in Irradiated Areas: a Pilot Study
Status: RECRUITING
Conditions: Recurrent Head and Neck Cancer|Local Cryotherapy Treatment
Interventions: PROCEDURE: local cryotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training
Status: RECRUITING
Conditions: Ventilator Weaning|Respiration, Artificial|Respiratory Muscles|Respiratory Failure|Critical Care
Interventions: DIAGNOSTIC_TEST: Inspiratory hold|DIAGNOSTIC_TEST: Expiratory hold|DIAGNOSTIC_TEST: Ultrasound of respiratory muscles|OTHER: PEEP 10|OTHER: PEEP 5|OTHER: PEEP 0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: HQP1351
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Transcranial Electrical Stimulation (TES) in Patients With Chronic Tinnitus
Status: UNKNOWN
Conditions: Tinnitus|Depression|Depressive Disorder|Hearing Disorders|Otorhinolaryngologic Diseases
Interventions: DEVICE: transcranial electrical stimulation (TES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome
Status: UNKNOWN
Conditions: Meige Syndrome|Meigs Syndrome|Meige Disease|Meig Syndrome|Blepharospasm|Blepharospasm of Left Eyelid|Blepharospasm of Right Eyelid|Blepharospasm of Both Eyelids|Blepharospasm Oromandibular Dystonia
Interventions: PROCEDURE: pallidotomy|PROCEDURE: deep brain stimulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Childhood Asthma Perception Study
Status: COMPLETED
Conditions: Asthma|Childhood Asthma
Interventions: BEHAVIORAL: PEF Feedback|BEHAVIORAL: Control Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus
Status: TERMINATED
Conditions: Barrett's Esophagus|Esophageal Neoplasms
Interventions: DEVICE: Radiofrequency Ablation(RFA) by HALO device.|DEVICE: Endoscopic mucosal resection(EMR) by mucosectomy kit.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Grafting of Epidermolysis Bullosa Wounds Using Cultured Revertant Autologous Keratinocytes
Status: WITHDRAWN
Conditions: Epidermolysis Bullosa
Interventions: PROCEDURE: Grafting of Autologous Cultured Revertant Keratinocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Oral Bioequivalence Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)
Interventions: DRUG: Vortioxetine Hemihydrobromide Orally Disintegrating Tablets|DRUG: Vortioxetine Hydrobromide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Back Pain.
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Buprenorphine transdermal delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh
Status: UNKNOWN
Conditions: Loop Ileostomy Closure
Interventions: PROCEDURE: MESH|PROCEDURE: NO MESH|RADIATION: Post-operative Imaging|RADIATION: Pre-operative Imaging|OTHER: Blood Test and C-reactive protein at 4th day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Strength Exercise on Fall Risk in Elderly With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia; Alzheimer's Type (Etiology)|Fall Risk|Elderly|Resistance Training
Interventions: PROCEDURE: Strength exercise|OTHER: Usual treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of RA101495 for Patients With PNH Who Have Completed a Zilucoplan (RA101495) Clinical Study
Status: TERMINATED
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: Zilucoplan (RA101495)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-Feedback Action of Growth Hormone, PP and PYY on Ghrelin in Bulimia
Status: ENROLLING_BY_INVITATION
Conditions: Eating Disorder|Bulimia Nervosa
Interventions: DRUG: Acipimox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|ATM Gene Mutation|BRCA1 Gene Mutation|BRCA2 Gene Mutation|Metastatic Malignant Neoplasm|PALB2 Gene Mutation|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
Status: COMPLETED
Conditions: Uterine Atony|Post-partum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Non-Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 5 mg/500 mg METAGLIP™ Tablets|DRUG: 5 mg/500 mg Glipizide Metformin Hydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Pac-12 Bodies in Motion
Status: ACTIVE_NOT_RECRUITING
Conditions: Effectiveness of BIM in Reducing Disordered Eating Among Student Athletes|Effectiveness of BIM in Reducing Body Image Concerns Among Student Athletes|Effectiveness of BIM Improving Psychological Well-Being Among Student Athletes
Interventions: BEHAVIORAL: Bodies in motion intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Respiratory Physiotherapy Allow for Earlier Withdrawal of Mechanical Ventilation in Respiratory Resuscitation Service?
Status: TERMINATED
Conditions: Respiratory Physiotherapy|Resuscitation
Interventions: OTHER: Study on patients with respiratory resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Heart Surgery
Status: UNKNOWN
Conditions: Opioid Use
Interventions: PROCEDURE: deep parasternal intercostal plane block|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study
Status: ENROLLING_BY_INVITATION
Conditions: Moral Injury Syndrome
Interventions: BEHAVIORAL: Building Spiritual Strength|BEHAVIORAL: Present Centered Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: De-escalation of Anti-TNF Therapy in Inflammatory Bowel Disease
Status: ENROLLING_BY_INVITATION
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Colitis, Ulcerative
Interventions: BIOLOGICAL: Infliximab|BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamotrigine Cognitive Function Study in Adult Untreated Epilepsies
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: lamotrigine (Lamictal)|DRUG: Carbamazepine (Tegretol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess CSL787 in Non-cystic Fibrosis Bronchiectasis (NCFB)
Status: COMPLETED
Conditions: Noncystic Fibrosis Bronchiectasis (NCFB)
Interventions: BIOLOGICAL: CSL787|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lymphadenectomy for Pancreatic Head Cancer: Standard or Extended?
Status: COMPLETED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Pancreaticoduodenectomy with Standard lymphadenectomy|PROCEDURE: Pancreaticoduodenectomy with Extended lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Amount of Root Coverage Following The Use of VISTA Technique Versus Coronally Advanced Flap in Combination With Subepithelial Connective Tissue Graft for Management of Multiple Gingival Recessions
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: vestibular incision subperiosteal tunnel access|PROCEDURE: Coronally advanced flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Quinapril or Quinapril Plus Hydrochlorothiazide in Patients With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: quinapril 20 mg|DRUG: quinapril 20 mg plus hydrochlorothiazide 12.5 mg|DRUG: quinapril 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Gliomas
Interventions: DRUG: Vandetanib|RADIATION: Fractionated Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Fluoxetine Hydrochloride Delayed-Release Capsules 90 mg of Dr. Reddy's Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fluoxetine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IS Reduces Rib Fracture Complications
Status: COMPLETED
Conditions: Hemothorax; Traumatic|Rib Fractures|Rib Trauma
Interventions: DEVICE: incentive spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of an Oral Nutritional Supplement on Lean Body Mass in Healthy Older Subjects.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: ONS without AN777|OTHER: ONS containing AN777
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Immunogenicity, Safety and Tolerability of a Fully Liquid Pentavalent (DTwP-Hib-Hep B) Vaccine in Infants 6-8 Weeks of Age
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Hemophilus Influenzae B
Interventions: BIOLOGICAL: DTwP-HepB-Hib Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease
Status: RECRUITING
Conditions: Diseases of Mitral and Aortic Valves|Rheumatic Disorders of Mitral and Aortic Valves|Other Congenital Malformations of Aortic and Mitral Valves|Valvular Heart Disease (Aortic and Mitral Valves)|Mitral Valve Insufficiency and Aortic Valve Insufficiency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Connecting Contact Lenses and Digital Technology
Status: COMPLETED
Conditions: Asthenopia|Contact Lenses|Ocular Accommodation|Convergence, Excess
Interventions: DEVICE: Test Daily Disposable Soft Contact Lenses|DEVICE: Control Daily Disposable Soft Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17)
Status: RECRUITING
Conditions: Rectal Cancer|Ileostomy; Functional Disturbance
Interventions: PROCEDURE: Tailored use of defunctioning stoma after TME|PROCEDURE: Systematic use of defunctioning stoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changing Health Through Food Support for Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Food Insecurity
Interventions: OTHER: Food support|OTHER: Nutritional Counseling and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Brain Stimulation as an Innovative Treatment for Chronic Neglect Patients
Status: COMPLETED
Conditions: Spatial Neglect
Interventions: DEVICE: Transcranial Alternating Current Stimulation (tACS)|BEHAVIORAL: Visual Scanning Training (VST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects|Drug Interactions|Pharmacokinetics of ASP015K
Interventions: DRUG: ASP015K|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling
Status: COMPLETED
Conditions: Skin Laxity
Interventions: DEVICE: Dermal Handpiece
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transcranial Direct Current Stimulation on Visual Attention in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Nicotine Content Cigarettes in Vulnerable Populations: Women of Reproductive Age
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: OTHER: Varying the nicotine content of cigarettes|OTHER: E-Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gingival Recession Coverage With and Without Emdogain
Status: COMPLETED
Conditions: Gingival Recession|Emdogain
Interventions: DEVICE: Recession coverage without Emdogain|DEVICE: Recession coverage with Emdogain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Smokers With Sleep Problems
Status: COMPLETED
Conditions: Nicotine Dependence|Cigarette Smoking|Insomnia
Interventions: BEHAVIORAL: Cognitive-Behavioral Counseling|BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status
Status: RECRUITING
Conditions: NSCLC Stage IV|KRAS P.G12C
Interventions: DRUG: Adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094
Status: COMPLETED
Conditions: Hunter Syndrome
Interventions: DRUG: Idursulfase-IT|DRUG: Elaprase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHJ002 Sterile Ophthalmic Solution for Myopia Control
Status: NOT_YET_RECRUITING
Conditions: Myopia, Progressive
Interventions: DRUG: SHJ002|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: cyclosporine|DRUG: pravastatin sodium|DRUG: mitoxantrone hydrochloride|DRUG: etoposide|PROCEDURE: bone marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an RBAC Supplement (BRM4) on NAFLD
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: rice bran arabinoxylan compound (RBAC)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Trigeminal Nerve Stimulation for ADHD
Status: RECRUITING
Conditions: Attention-Deficit Hyperactivity Disorder
Interventions: DEVICE: Active eTNS|DEVICE: Sham eTNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: mFOLFOXIRI plus Bevacizumab|DRUG: mFOLFOX6 Plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FAK (Defactinib) and PD-1 (Pembrolizumab) Inhibition in Advanced Solid Malignancies (FAK-PD1)
Status: UNKNOWN
Conditions: Carcinoma, Non-small-cell Lung|Mesothelioma|Pancreatic Neoplasms
Interventions: DRUG: Defactinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients
Status: COMPLETED
Conditions: Post Operative Nausea and Vomiting (PONV)|Adenotonsillectomy
Interventions: DRUG: Gabapentin as premedication|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-arterial Albumin in Acute Ischemic Stroke After Endovascular Treatment for
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: intra-arterial infusion albumin|OTHER: mechanical thrombectomy and a standard clinical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Magnetic Resonance Imaging Versus Computed Tomography to Guide Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Stenosis
Interventions: DIAGNOSTIC_TEST: TAVR-CMR|DIAGNOSTIC_TEST: TAVR-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Status: COMPLETED
Conditions: Cancer, Rectum
Interventions: PROCEDURE: Anterior resection for upper rectal cancer in obese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Cerebrovascular Control
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: NOS Inhibition|DRUG: ET-1 Inhibition|DRUG: NOS Inhibition Placebo|DEVICE: 3 Tesla MRI|DEVICE: Intravenous Catheter|OTHER: Oral Glucose Tolerance Test|DRUG: ET-1 Inhibition Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Non-Randomized Study of Internal Radiation Therapy to the Liver in Patients With Primary Liver Cancer for Whom Surgery is Not Possible.
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DEVICE: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment
Status: COMPLETED
Conditions: Depression|Post-COVID-19 Syndrome|Depression Mild|Depression Moderate
Interventions: DIETARY_SUPPLEMENT: DEPREXIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Virtual Gait System Intervention in Motor Function in People With Incomplete Spinal Cord Injury.
Status: ACTIVE_NOT_RECRUITING
Conditions: Incomplete Spinal Cord Injury
Interventions: OTHER: Virtual Gait|OTHER: Physical Exercise|OTHER: Documental projection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Inflammation and Carbohydrate Digestion in Autistic Children
Status: UNKNOWN
Conditions: Autism|Inflammation
Interventions: OTHER: Stool collection|OTHER: Administration of carbohydrate solution during clinically indicated endoscopy|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Cereal Products in Elderly People
Status: COMPLETED
Conditions: Old Person
Interventions: OTHER: Two samples of saliva|OTHER: Chewing behaviour|OTHER: Study of the food bolus|OTHER: Mouthfeel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2 Study of T-DXd in the Neoadjuvant Treatment for Patients With HER2 Positive Gastric and GEJ Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Trastuzumab Deruxtecan (T-DXd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers
Status: COMPLETED
Conditions: SARS-CoV 2|COVID-19
Interventions: OTHER: Serologic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reduction of Perineal Pain After Vaginal Birth With Black Tea: Pilot Randomized Study
Status: COMPLETED
Conditions: Perineal Pain
Interventions: OTHER: Frozen perineal pad|OTHER: Warm water soaked Black Tea Bags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Autologous Bone Marrow Mesenchymal Stem Cells Transplantation Via Hepatic Artery in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: PROCEDURE: Hepatic artery infusion|PROCEDURE: Conserved Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of Human Papillomavirus Assays and Collection Devices for Self-samples and Urine Samples
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia Grade 2/3
Interventions: DEVICE: Colli-Pee|DEVICE: Multi-Collect Swab|DEVICE: Evalyn Brush|DEVICE: Qvintip|DIAGNOSTIC_TEST: Abbott RealTime High Risk HPV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of LymphoStat-B (Belimumab) in Subjects With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Placebo|DRUG: Belimumab 1 mg/kg|DRUG: Belimumab 4 mg/kg|DRUG: Belimumab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Frequency Light, Sound, and Tactile Stimulation to Improve Motor and Cognitive Deficits in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: GENUS device (Active Settings)|DEVICE: GENUS device (Sham settings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE