pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic Leiomyosarcoma
Status: COMPLETED
Conditions: Metastatic Leiomyosarcoma
Interventions: DRUG: Mocetinostat|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Safety and P2Y12 Receptor Inhibition Effects of Ticagrelor and Clopidogrel in Vietnamese Patient
Status: WITHDRAWN
Conditions: Coronary Heart Disease
Interventions: DRUG: 90 mg Ticagrelor|DRUG: 75mg Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2b Study to Evaluate the Efficacy and Safety of ISB 830 in Adults With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: ISB 830 - Part 1 Group 1|DRUG: ISB 830 - Part 1 Group 2|DRUG: ISB 830 - Part 1 Group 3|DRUG: Placebo - Part 1 Group 4|DRUG: ISB 830 - Part 2 Group 5|DRUG: Placebo - Part 2 Group 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding for Intraoperative Photodynamic Therapy of Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Gliolan|DEVICE: Intraoperative PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Resveratrol Improve Insulin Sensitivity and Preserve Beta Cell Function Following Gestational Diabetes?
Status: UNKNOWN
Conditions: Gestational Diabetes
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Bioavailability of Marine Based Collagen Peptides in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Collagen Peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Vitamin D Supplementation in Multiple Sclerosis (EVIDIMS)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Verum arm receiving Vitamin D oil|DRUG: low dose arm receiving neutral oil and 400 IU/g of Vitamin D every second day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Asses Mass Balance And Absolute Bioavailability Of 14C PF-06826647 In Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 14C-PF-06826647-LR 600 mg PO|DRUG: PF-06826647 600 mg PO|DRUG: 14C-PF-06826647 100 ug IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Photobiomodulation for the Prevention of Radiation Induced Oral Mucositis
Status: RECRUITING
Conditions: Mucositis Oral|Head and Neck Cancer|Radiation Dermatitis
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Evaluation of the Non-invasive ICP HeadSense Monitor in TBI Patients Undergoing Invasive ICP Monitoring
Status: COMPLETED
Conditions: Brain Injuries|Intracranial Hypertension
Interventions: DEVICE: HS-1000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Sleep Disturbance|Fatigue|Inflammatory Bowel Disease
Interventions: BEHAVIORAL: Behavioral Counseling|DRUG: bupropion-SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cysteamine-pantetheine Disulfide (TTI-0102) in Mild to Moderate COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: TTI-0102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Formoterol in Patients With COPD Compared With Placebo in Patients in Japan, EU
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Formoterol Turbuhaler® 4.5mg|DRUG: Formoterol Turbuhaler® 9 mg|DRUG: Turbuhaler® placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Modulation of Belief Salience
Status: COMPLETED
Conditions: Haloperidol|Placebo|L-DOPA
Interventions: DRUG: Placebo - Cap|DRUG: L-dopa|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy and Safety of Mebendazole for the Treatment of Helminth Infections in Pediatric Participants
Status: COMPLETED
Conditions: Helminth Infections
Interventions: DRUG: Mebendazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Perioperative/Postoperative Complications
Interventions: BEHAVIORAL: patient interviewing to obtain menstrual history|PROCEDURE: blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 13-valent Pneumococcal Conjugate Vaccine Study in Adults => 50 Years of Age in Mexico
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: vaccine-13vPnC|BIOLOGICAL: vaccine-13vPnC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU
Status: NOT_YET_RECRUITING
Conditions: Intensive Care Unit|Acute Kidney Injury|Ultrasound
Interventions: OTHER: Renal microcirculation quantitatively assessed by Contrast-enhanced ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gene Expression and FDG PET/MRI in Evaluating Treatment Response in Patients With Locally Advanced Rectal Cancer Undergoing Chemotherapy and Radiation Therapy Before Surgery
Status: TERMINATED
Conditions: Rectal Neoplasms
Interventions: RADIATION: fludeoxyglucose F 18|DEVICE: positron emission tomography|DEVICE: magnetic resonance imaging|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes
Status: NOT_YET_RECRUITING
Conditions: Obesity|Dapagliflozin Adverse Reaction|Weight Loss|Effect of Drug
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: ABI-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal LFG316 in Patients With Advanced Age-related Macular Degeneration
Status: COMPLETED
Conditions: Advanced Age-related Macular Degeneration
Interventions: BIOLOGICAL: LFG316|BIOLOGICAL: LFG316|BIOLOGICAL: LFG316|BIOLOGICAL: LFG316
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma
Status: UNKNOWN
Conditions: Morton Neuroma
Interventions: DEVICE: Cryoablation|PROCEDURE: Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Assessment in Patient Recovered From COVID-19 and Recovery of Autonomic Nervous System in Association With the Severity of the Disease
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Non invasive cardiovascular monitoring with CNAP device of arterial pressure, ECG and respiratory activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Trial of Endobronchial Ultrasound-Guided Transbronchial Needle Injection of Cisplatin for Stage IV Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer Metastatic
Interventions: DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Status: COMPLETED
Conditions: Intraoperative Floppy Iris Syndrome|Cataract|Age-related Cataract|Adrenergic Receptor Antagonist Adverse Reaction
Interventions: DRUG: 1% Atropine drops|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Clonidine in the Sedation of Mechanically Ventilated Children
Status: COMPLETED
Conditions: Respiration, Artificial|Critical Illness|Conscious Sedation|Deep Sedation
Interventions: DRUG: clonidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency
Status: NOT_YET_RECRUITING
Conditions: Parents|Self Efficacy|Mental Health Literacy|Psychiatric Emergency
Interventions: BEHAVIORAL: iPEACE: Intervention for Parent Education about Care after the ED|BEHAVIORAL: Text Messaging Reminders Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TUC3PII-01_TU2670 Phase IIa Clinical Study
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Placebo Comparator: Placebo|DRUG: Active Comparator: TU2670 320mg|DRUG: Active Comparator: TU2670 240mg|DRUG: Active Comparator: TU2670 120mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Cancer and Central Lymph Node Metastases Detection Using Bevacizumab-IRDye800CW
Status: COMPLETED
Conditions: Thyroid Carcinoma|Surgery
Interventions: DRUG: Bevacizumab-IRDye800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1 Study of DD01 in Overweight/Obese Subjects With T2DM and NAFLD
Status: COMPLETED
Conditions: Overweight and Obesity|Type2 Diabetes|NAFLD
Interventions: DRUG: DD01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Mirabegron|OTHER: B Complex Plus Vitamin C Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes
Status: COMPLETED
Conditions: Cytochrome|Pharmacokinetics
Interventions: DRUG: caffeine, efavirenz, losartan, omeprazole, metoprolol, chlorzoxazone and midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Ultrasound-guided Transuterine Vaginal Biopsy Technique in Uterine Fibromatous Disease
Status: NOT_YET_RECRUITING
Conditions: Fibroid|Uterine Corpus Smooth Muscle Neoplasm
Interventions: PROCEDURE: Echoguided transuterine vaginal biopsy performed before myomectomy or hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quick Skin Sealant in Closure of Surgical Wound After Laparoscopic Surgery
Status: UNKNOWN
Conditions: Complications of Surgical Procedures|Surgical Site Infection|Gastric Cancer|Colorectal Cancer|Gastrointestinal Stromal Tumor|Inflammatory Bowel Disease|Diverticula
Interventions: PROCEDURE: Laparoscopic surgery|DEVICE: Skin sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Colistin and Rifampicin for MDR-Acinetobacter
Status: COMPLETED
Conditions: Infection Due to Resistant Bacteria|Pneumonia, Ventilator-Associated|Hospital Acquired Pneumonia|Infection of Bloodstream|Infectious Disease of Abdomen
Interventions: DRUG: Colistin|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Parenteral Nutrition With Different Lipid Emulsions in Preterm Infants
Status: UNKNOWN
Conditions: Preterm Infant
Interventions: DRUG: ClinOleic|DRUG: Lipofundin|DRUG: Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electronic Catheter Stethoscope
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Gynecologic Cancers|Uterine Leiomyomata|Adenomyosis|Endometrial Hyperplasia|Other Abnormal Uterine and Vaginal Bleeding|Pelvic Mass|Pelvic Pain
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Function, Quality of Life, Glycemia in Diabetics With Dementia
Status: WITHDRAWN
Conditions: Diabetes Mellitus|Alzheimer's Disease|Apathy|Dementia
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Assess Efficacy and Safety of Olaparib in Confirmed Genetic BRCA1 or BRCA2 Mutation Pats
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian|Breast|Prostate|Pancreatic|Advanced Tumours
Interventions: DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Carcinoid Tumors|Neuroblastoma|Medulloblastoma
Interventions: DRUG: 68Ga-DOTATOC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma|Non-small Cell Lung Cancer|Triple Negative Breast Cancer|Colorectal Carcinoma|Glioblastoma Multiforme
Interventions: DRUG: ABBV-221
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of Aerosols in Residences Study
Status: COMPLETED
Conditions: Endothelial Dysfunction|Systemic Inflammation
Interventions: DEVICE: HEPA Filter|DEVICE: HEPA Filtration Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pot-Cast: Thrombosis Prophylaxis During Plaster Cast Lower Leg Immobilisation
Status: COMPLETED
Conditions: Deep Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: LMWH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trans-RosaLEE Study: a Biomarker-directed, Translational Study
Status: RECRUITING
Conditions: Advanced or Metastatic Breast Cancer (BC)
Interventions: GENETIC: Pre-treatment biopsy|GENETIC: Post treatment biopsy|GENETIC: Pre treatment blood sampling|GENETIC: Post treatment blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electric Field Navigated 1hz Rtms for Post-stroke Motor Recovery Trial
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Nexstim NBS guided active rTMS|DEVICE: Nexstim NBS guided sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on the Frequency and Intensity of Migraine Attacks and Intestinal Permeability
Status: UNKNOWN
Conditions: Migraine
Interventions: DIETARY_SUPPLEMENT: EcologicBarrier|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levels of 'Hypophosphatemia Affect Outcome of Septic Patients in ICU
Status: UNKNOWN
Conditions: Hypophosphatemia
Interventions: DRUG: Glycophos (Sodium Glycerophosphate)|DRUG: Antibiotics|DRUG: Inotropes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bone Disease in Severely Burned Children
Status: TERMINATED
Conditions: Burn
Interventions: DRUG: Tetracycline|RADIATION: Duel Energy X-Ray Absorptiometry (DEXA)|PROCEDURE: Bone Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube Versus Laryngeal Mask Airway for Esophagogastroduodenoscopy
Status: COMPLETED
Conditions: Airway Morbidity
Interventions: DEVICE: LMA|DEVICE: ETT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Travoprost APS Versus Xalatan® in Patient Reported Outcomes and Ocular Surface Health
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost APS 40 micrograms/ml eye drop solution|DRUG: Latanoprost 50 micrograms/ml eye drop solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Fabrazyme® and Arbs and ACE Inhibitor Treatment (FAACET) Study
Status: COMPLETED
Conditions: Fabry Disease|Proteinuria
Interventions: DRUG: enalapril and other angiotensin converting enzyme inhibitors; losartan and other angiotensin receptor blockers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of GC019F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALL
Status: NOT_YET_RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: GC019F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture
Status: RECRUITING
Conditions: Hip Fractures|Pain, Acute|Hip Fracture Surgery|Delirium in Old Age|Pain Intensity
Interventions: PROCEDURE: Post-admission FICB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DRUG: Ranolazine|DRUG: Ranolazine|DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the APTIMA® HPV Assay Using the TIGRIS® System
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: DEVICE: APTIMA HPV Assay|DEVICE: FDA-Approved HPV DNA Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Open-Label Study of the Long-Term Safety of Dapoxetine HCl in the Treatment of Rapid Ejaculation
Status: COMPLETED
Conditions: Ejaculation|Erectile Dysfunction|Sexual Dysfunction
Interventions: DRUG: dapoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Biomarker Panel to Assess Choline Nutritional Status
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: 25% Cho diet|OTHER: 50% Cho diet|OTHER: 100% Cho diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Tislelizumab Plus Anlotinib for Immunotherapy Resistant Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Colo-rectal Cancer
Interventions: DRUG: Tislelizumab|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga On Dyspnea, Sleep And Fatıgue In Chronıc Respıratory Dıseases
Status: COMPLETED
Conditions: Chronic Respiratory Disease
Interventions: OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Digestive Tract Cancer and CIPN
Status: RECRUITING
Conditions: Digestive Tract Cancer|Chemotherapy-induced Peripheral Neuropathy|Remote Exercise
Interventions: OTHER: remote home-based exercise therapy group|OTHER: supervised exercise therapy group|OTHER: regular care group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of OT-135P (IOPtiMateTM) : Beam Manipulating System for CO2 Laser Assisted Non-Penetrating Glaucoma Surgery
Status: UNKNOWN
Conditions: Open Angle Glaucoma|Pseudo-Exfoliative Glaucoma
Interventions: DEVICE: Laser Assisted Non-penetrating glaucoma surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Laser Stimulation on Wound Healing of Human Palatal Tissue
Status: TERMINATED
Conditions: Healing Surgical Wounds|Pain Measurement
Interventions: DEVICE: J. Morita AdvErl Evo Er:YAG laser|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Pancreatic Neuroendocrine Tumors
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Aortic vaLve surgEry Versus wAtchful waitiNg Strategy in Severe Asymptomatic aOrtic reguRgitation
Status: RECRUITING
Conditions: Aortic Valve Regurgitation
Interventions: PROCEDURE: State of art aortic valve surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Gemcitabine Combined With Vinorelbine as First Line Chemotherapy for Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: gemcitabine|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Delivery of a Mindfulness-based Intervention for Tics
Status: RECRUITING
Conditions: Tourette Syndrome|Tourette's Disorder|Chronic Motor Tic Disorder|Chronic Vocal Tic Disorder|Persistent Motor Tic Disorder|Persistent Vocal Tic Disorder|Persistent Tic Disorder|Tic Disorders
Interventions: OTHER: mindfulness-based intervention for tics (MBIT)|OTHER: psychoeducation with relaxation and supportive therapy (PRST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study
Status: RECRUITING
Conditions: Uterine Fibroid|Pregnancy Related
Interventions: PROCEDURE: Laparotomic myomectomy during pregnancy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Memantine-enhanced Buprenorphine Treatment for Opioid-dependent Young Adults
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Memantine|DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Doses of Ergocalciferol Supplementation for Treatment of Hypovitaminosis D in Adults
Status: UNKNOWN
Conditions: Vitamin D2 Supplementation in Vitamin D Insufficiency
Interventions: DRUG: Ergocalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers
Status: TERMINATED
Conditions: Breast Cancer|Cognitive/Functional Effects|Fatigue|Long-term Effects Secondary to Cancer Therapy in Adults
Interventions: PROCEDURE: assessment of therapy complications|PROCEDURE: cognitive assessment|PROCEDURE: fatigue assessment and management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Active-controlled, Clinical Trial to Assess Central Hemodynamic Effects of Bisoprolol in Hypertensive Patients (Central Hemodynamic Assessment Measured in Patient With HypertensION [CHAMPION])
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Bisoprolol|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy of HAIC（GEMOX） Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Adebrelimab|DRUG: Lenvatinib|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of Personalised Music in Dementia - a Feasibility Study
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: Personalised music listening|BEHAVIORAL: Using fMRI to investigate the effect of listening to personalised music evoking positive emotional response on brain activation|BEHAVIORAL: Personalised music listening in the community
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough
Status: COMPLETED
Conditions: Surgery|Anesthesia
Interventions: DRUG: Desflurane|DRUG: Administration of Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Colchicine in Moderate Symptomatic COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Ventilator in Long-term Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: maintenance negative pressure ventilation (Philips Respironics Lifecare NEV-100)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dorsal and Volar Surgeries Preferred in Scaphoid Pseudorthrosis Comparison of Effects on Kinematics
Status: COMPLETED
Conditions: Scaphoid Fracture
Interventions: PROCEDURE: SCAHOİD GRAPHONAGE WITH AUTOGRAPH FROM DİSTAL RADİUS BY DORSAL APPROACH|PROCEDURE: SCAHOİD GRAPHONAGE WITH AUTOGRAPH FROM DİSTAL RADİUS BY VOLAR APPROACH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Acute Gastrointestinal Tolerability Following a Single Serving of a Novel Dietary Fiber
Status: COMPLETED
Conditions: Signs and Symptoms, Digestive
Interventions: OTHER: Novel Fiber|OTHER: Positive Fiber control|OTHER: Negative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Polyinosinic-Polycytidylic Acid-poly-L-lysine Carboxymethylcellulose (Poly-ICLC) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial
Status: RECRUITING
Conditions: Graft Vs Host Disease|Acute-graft-versus-host Disease|Chronic Graft-versus-host-disease
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Tumor Associated Lymph Node T Cell|Immunotherapy
Interventions: DRUG: Tumor Associated Lymph node T cell|DRUG: cyclophosphamide|DRUG: IL-2|DRUG: Serplulimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Status: RECRUITING
Conditions: Ischemic Heart Disease|Non STEMI|Angina Pectoris, Unstable
Interventions: PROCEDURE: CCTA|PROCEDURE: Conventional ICA|OTHER: Team-based interventional triage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between YHR1705 and YHR1706
Status: COMPLETED
Conditions: Dyslipidemia|Type 2 Diabetes Mellitus
Interventions: DRUG: YHR1705|DRUG: YHR1706|DRUG: YHR1705+YHR1706
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravascular Administration of Mesenchymal Stromal Cells Derived From Wharton's Jelly of the Umbilical Cord on Systemic Immunomodulation and Neuroinflammation After Traumatic Brain Injury.
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Mesenchymal Stromal Cells (MSC)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
Status: RECRUITING
Conditions: Advanced Solid Tumor|Urinary Bladder Neoplasm|Triple Negative Breast Neoplasms|Carcinoma, Non-Small-Cell Lung|Ovarian Neoplasm
Interventions: DRUG: BT8009|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Chemotherapy With S1 Plus Paclitaxel-albumin on Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Neoadjuvant Chemotherapy
Interventions: DRUG: S1,|DRUG: Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Soluble Corn Fiber Supplementation for 1 Year on Bone Metabolism in Adolescents
Status: RECRUITING
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Soluble Corn Fiber (SCF) without Calcium|COMBINATION_PRODUCT: Soluble Corn Fiber (SCF) + Calcium|DIETARY_SUPPLEMENT: Placebo|COMBINATION_PRODUCT: Placebo + calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NIRS-IVUS to Improve Assessment of Coronary Artery Disease Severity in Patients Referred for Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Coronary Artery Disease|Aortic Stenosis, Severe
Interventions: DIAGNOSTIC_TEST: Combined near-infrared spectroscopy and intravascular ultrasound imaging (NIRS-IVUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib in Treating Patients With Unresectable Liver, Bile Duct, or Gallbladder Cancer
Status: COMPLETED
Conditions: Adult Primary Cholangiocellular Carcinoma|Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Evacuation of Subacute and Chronic Supratentorial Deep Hypertensive Intracerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Hypertensive Intracerebral Hemorrhage
Interventions: PROCEDURE: Robotic Assisted Evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Multi-center Safety & Efficacy Study of Low Frequency Magnetic Fields to Treat Unresponsive Diabetic Foot Ulcers.
Status: COMPLETED
Conditions: Neuropathic Diabetic Ulcer - Foot
Interventions: DEVICE: Forearm tissue exposure with ELF-MF|DEVICE: Thorax tissue exposure with ELF-MF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Inflammatory and Anti-Platelet Effect of Clopidogrel and Aspirin vs Aspirin Alone in Symptomatic Polyvascular Disease and in Patients With Multiple Recurrent Cardiovascular Events
Status: UNKNOWN
Conditions: Polyvascular Disease|Cardiovascular Disease
Interventions: DRUG: aspirin|DRUG: clopidogrel|DRUG: clopidogrel plus aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Opioid Free Anesthesia on the Quality of Early Recovery
Status: NOT_YET_RECRUITING
Conditions: Opioid-free Anesthesia
Interventions: DRUG: T group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin and Etoposide in Combination With Vorinostat for Patients With Extensive Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Vorinostat, Carboplatin, Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents
Status: COMPLETED
Conditions: Allergic Contact Dermatitis
Interventions: DIAGNOSTIC_TEST: Panels 1.3, 2.2 and 3.2 experimental allergens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: DRUG: Cyclophosphamide|DRUG: Itacitinib|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Quality-of-Life Assessment|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Anaplastic Ependymoma|Anaplastic Ganglioglioma|Anaplastic Meningioma|Anaplastic Oligodendroglioma|Pleomorphic Xanthoastrocytoma, Anaplastic|Atypical Teratoid/Rhabdoid Tumor|Brain Cancer|Brain Tumor|Central Nervous System Neoplasms|Choroid Plexus Carcinoma|CNS Embryonal Tumor With Rhabdoid Features|Ganglioneuroblastoma of Central Nervous System|CNS Tumor|Embryonal Tumor of CNS|Ependymoma|Glioblastoma|Glioma|Glioma, Malignant|Medulloblastoma|Medulloblastoma; Unspecified Site|Medulloepithelioma|Neuroepithelial Tumor|Neoplasms|Neoplasms, Neuroepithelial|Papillary Tumor of the Pineal Region (High-grade Only)|Pediatric Brain Tumor|Pineal Parenchymal Tumor of Intermediate Differentiation (High-grade Only)|Pineoblastoma|Primitive Neuroectodermal Tumor|Recurrent Medulloblastoma|Refractory Brain Tumor|Neuroblastoma. CNS|Glioblastoma, IDH-mutant|Glioblastoma, IDH-wildtype|Medulloblastoma, Group 3|Medulloblastoma, Group 4|Glioma, High Grade|Neuroepithelial Tumor, High Grade|Medulloblastoma, SHH-activated and TP53 Mutant|Medulloblastoma, SHH-activated and TP53 Wildtype|Medulloblastoma, Chromosome 9q Loss|Medulloblastoma, Non-WNT Non-SHH, NOS|Medulloblastoma, Non-WNT/Non-SHH|Medulloblastoma, PTCH1 Mutation|Medulloblastoma, WNT-activated|Ependymoma, Recurrent|Glioma, Recurrent High Grade|Glioma, Recurrent Malignant|Embryonal Tumor, NOS|Glioma, Diffuse Midline, H3K27M-mutant|Embryonal Tumor With Multilayered Rosettes (ETMR)|Ependymoma, NOS, WHO Grade III|Ependymoma, NOS, WHO Grade II|Medulloblastoma, G3/G4|Ependymoma, RELA Fusion Positive
Interventions: DRUG: Gemcitabine|DRUG: ribociclib|DRUG: sonidegib|DRUG: trametinib|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axicabtagene Ciloleucel Expanded Access Study
Status: APPROVED_FOR_MARKETING
Conditions: Relapsed/Refractory Diffuse Large B Cell Lymphoma|Relapsed/Refractory Primary Mediastinal B Cell Lymphoma|Relapsed/Refractory Transformed Follicular Lymphoma|Relapsed/Refractory High-Grade B-Cell Lymphoma
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel
Study Type: EXPANDED_ACCESS
Clinical trial: Effects of Agility and Perturbation Based Training in Addition to Routine Physical Therapy
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression|Bipolar I Depression|Bipolar II Depression
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Tolerability Study of Bortezomib in Combination With Rituximab Standard Therapy in Participants With Relapsed or Refractory Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Bortezomib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Health Plan-Level Care Management for Solo & Small Practices
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: BEHAVIORAL: Chronic Care Model for Mood Disorders|OTHER: Educational Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole
Status: SUSPENDED
Conditions: Candidiasis, Invasive|Candidemia
Interventions: DRUG: SCY-078|DRUG: Fluconazole|DRUG: Echinocandin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract
Status: COMPLETED
Conditions: Age Related Cataracts
Interventions: DRUG: EDTA Ophthalmic Solution 2.6%|DRUG: EDTA Ophthalmic Solution 1.3%|DRUG: Saline Solution (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement in Gross Motor Function and Muscle Tone in Children With Cerebral Palsy Related to Neonatal Icterus
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: COMBINATION_PRODUCT: Stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMES for Rehab After Surgery
Status: COMPLETED
Conditions: Surgery|Vascular Diseases
Interventions: DEVICE: Revitive Medic Neuromuscular Stimulation Device|DEVICE: Revitive Medic Neuromuscular Stimulation Device (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements
Status: TERMINATED
Conditions: Advanced Cholangiocarcinoma|FGFR2 Gene Rearrangements
Interventions: DRUG: TAS-120|DRUG: Cisplatin/Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus
Status: COMPLETED
Conditions: End-Stage Renal Disease|Pruritus
Interventions: DRUG: Wheat|DRUG: Fumaria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identify the Usefulness of Peer-facilitated Versus Self-navigated Quit Tobacco Program for Youths.
Status: RECRUITING
Conditions: Tobacco Product Use
Interventions: BEHAVIORAL: Peer-facilitated tobacco cessation|BEHAVIORAL: Self-navigated tobacco cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis
Status: UNKNOWN
Conditions: Spinal Fractures
Interventions: DEVICE: Percutaneous Vertebral Augmentation of compression fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety of an Inactivated H5N1 Influenza Vaccine Administered in GelVac Nasal Powder to Healthy Young Adults
Status: COMPLETED
Conditions: Phase 1 Safety Study of GelVac Nasal Powder H5N1 Influenza Vaccine
Interventions: DRUG: GelVac™ nasal powder H5N1 influenza vaccine.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: High Risk Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|BIOLOGICAL: Filgrastim|DRUG: Fludarabine|DRUG: Idarubicin|BIOLOGICAL: Pegfilgrastim|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT