pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2)
Status: RECRUITING
Conditions: Systemic Inflammatory Response Syndrome
Interventions: BIOLOGICAL: Allogeneic thyTreg 5.000.000|BIOLOGICAL: Allogeneic thyTreg 10.000.000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation
Status: COMPLETED
Conditions: Hypovitaminosis D
Interventions: DEVICE: Standing Phototherapy Kiosk|DIETARY_SUPPLEMENT: D3 Oral supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Early Quality of Recovery
Status: COMPLETED
Conditions: Pneumoperitoneum|Neuromuscular Blockade|Surgery
Interventions: PROCEDURE: Low pressure pneumoperitoneum|DRUG: Rocuronium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy and Biological Therapy in Treating Patients With Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BIOLOGICAL: MOv-gamma chimeric receptor gene|BIOLOGICAL: aldesleukin|BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine for Treatment of Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: traditional Chinese medicine|DRUG: Placebo (gummeline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging of Injectate in Thoracic 2 Paravertebral Block
Status: UNKNOWN
Conditions: Cervical Spinal Stenosis
Interventions: PROCEDURE: Ultrasound probe sagittal group|PROCEDURE: Ultrasound probe transverse group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cultivando la Salud: A Breast and Cervical Cancer Screening Promotion Program for Low-Income Puerto Rican Women
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Cultivando La Salud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Randomized Clinical Trial About Use of 3D Laparoscopy Versus 2D Laparoscopy in Adrenal Surgery
Status: COMPLETED
Conditions: Adrenal Mass|Adrenal Adenoma|Adrenal Gland Neoplasms
Interventions: PROCEDURE: laparoscopic adrenalectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical and Cognitive Impairments in People Suffering From Long COVID
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2 Infection|Corona Virus Infection|Physical Disability|Cognitive Impairment|Cognitive Dysfunction|Quality of Life|Symptoms and Signs|Impairment
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Clinical Performance Evaluation of the In-Vitro Diagnostics Medical Device MaGIA IBC for the CombIned screENing of HIV, Hepatitis B and Hepatitis C
Status: RECRUITING
Conditions: Combined Point of Care Diagnostic of HIV, HBV and HCV
Interventions: DIAGNOSTIC_TEST: MagIA IBC test in capillary blood|DIAGNOSTIC_TEST: MagIA IBC test in other matrices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Lung CongestIon Symptoms in Advanced Heart Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: V-Wave Interatrial Shunt|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SuPA Mobility: Supporting Physical Activity for Mobility in Mobility-Limited Older Adults
Status: RECRUITING
Conditions: Limitation, Mobility|Older Adults
Interventions: BEHAVIORAL: Health Coaching Program|BEHAVIORAL: Health Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conjugated Linoleic Acid Supplementation Study
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Placebo oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy, Safety and Immunogenicity of GP40141 (GEROPHARM, Russia) in Patients With Immune Thrombocytopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Drug Effect|Safety Issues|Immunogenicity
Interventions: DRUG: GP404141|DRUG: Nplate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Robotic hemi-prostatectomy with urethral preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remote Ischemic Preconditioning on Major Organ Function in Patients With Coronary Artery Disease Undergoing Orthopedic Surgery
Status: COMPLETED
Conditions: Angina Pectoris|Myocardial Infarction
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carbetocin and Oxytocin in Elective Caesarean Section With High Risk of Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Effectiveness of Three Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Taken AZT
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine|DRUG: Zidovudine|DRUG: Zalcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8
Status: TERMINATED
Conditions: Cocaine Abuse|Opiate Dependence
Interventions: DRUG: Modafinil 200mg|DRUG: Modafinil 400mg|DRUG: Citalopram 20mg|DRUG: Citalopram 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
Status: COMPLETED
Conditions: Seizure Disorder, Partial
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Among HealthCare Workers (HCW) Vaccinated With Janssen Vaccine: the SWITCH Trial
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Vaccination once with Janssen vaccine (only priming)|BIOLOGICAL: Vaccination with Janssen vaccine followed with Janssen vaccine (homologous boosting).|BIOLOGICAL: Vaccination with Janssen vaccine followed with Moderna vaccine (heterologous boosting).|BIOLOGICAL: Vaccination with Janssen vaccine followed with Pfizer vaccine (heterologous boosting).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: First-in-human Safety Study of Hypoimmune Pancreatic Islet Transplantation in Adult Subjects With Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type1diabetes
Interventions: BIOLOGICAL: UP421
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: SYN-010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Oral RP7214, a DHODH Inhibitor, in Patients With Symptomatic Mild COVID-19 Infection.
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: RP7214 + Standard of care (SOC)|DRUG: Placebo + Standard of care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy After Radiotherapy in Elderly ESCC
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma by AJCC V8 Stage
Interventions: RADIATION: Radiotherapy|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Postop Temperature After Cesarean Delivery
Status: RECRUITING
Conditions: Temperature Change, Body|Cesarean Delivery|Spinal Anesthesia
Interventions: DEVICE: Warm air blower|OTHER: Control: Lower body blanket not attached to warm air blower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Vasodilation|Vasoconstriction
Interventions: DRUG: Bosentan|DRUG: Sitaxsentan|DRUG: Placebo|BIOLOGICAL: Endothelin-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: DRUG: Lemborexant 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women
Status: NOT_YET_RECRUITING
Conditions: Overweight or Obesity|Prediabetes or Diabetes|Prehypertension (Elevated Blood Pressure) or Hypertension|Resistance Training
Interventions: BEHAVIORAL: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor
Status: UNKNOWN
Conditions: Desmoid Tumor
Interventions: DRUG: Liposome doxorubicin|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sotalol, Tablets, 160 mg (Pharmtechnology LLC, Belarus), and Sotalex ®, Tablets, 160 mg (Bristol-Myers Squibb GmbH & Co. KGaA, Germany), in Healthy Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Sotalol|DRUG: Sotalex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer
Status: COMPLETED
Conditions: Liver Metastases
Interventions: BIOLOGICAL: anti-CEA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.
Status: COMPLETED
Conditions: Depression|Anxiety|Primary Health Care
Interventions: BEHAVIORAL: IntelliCare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoclip Papillaplasty Recover Sphincter of Oddi Function After Endoscopic Sphincterotomy for Bile Duct Gallstones
Status: UNKNOWN
Conditions: Sphincter of Oddi Function
Interventions: PROCEDURE: Endoclip papillaplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: melphalan|DRUG: methotrexate|DRUG: vincristine sulfate|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Nociception Level (NOL)-Guided Remifentanil Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity
Status: UNKNOWN
Conditions: Head and Neck Surgery|Maxillofacial Surgery
Interventions: OTHER: Entropy and NOL-Guided Goal Directed Anesthesia|OTHER: Standard of Care Group (Entropy and blinded NOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer
Status: COMPLETED
Conditions: Childhood Cancer
Interventions: RADIATION: fludeoxyglucose F 18|PROCEDURE: positron emission tomography|PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amikacin inhalation solution (BAY41-6551)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and PK of Repeated Doses of IRL201104 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: IRL201104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: BIOLOGICAL: AERAS-402|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Echocardiographic Evaluation of RV Injury in the ICU
Status: NOT_YET_RECRUITING
Conditions: Right Heart Failure, Unspecified|Critical Illness|ARDS, Human|Septic Shock
Interventions: DIAGNOSTIC_TEST: Echocardiography and central venous pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilates-Based Exercises Practised by Hybrid Telerehabilitation in Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of 50 and 100 IU Doses of Botox A Toxin Injection in BPH Patients.
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Botox injection in the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects
Status: UNKNOWN
Conditions: Advanced HBV-Related Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Icaritin|DRUG: HUACHANSU PIAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of InSan Bamboo Salt on Improvement of Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DIETARY_SUPPLEMENT: InSan Bamboo Salt|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neodjuvant Nivolumab and Lirilumab, Followed by Surgery, Followed by Adjuvant Nivolumab and Lirilumab, in SCCHN
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Nivolumab|DRUG: Lirilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection
Status: COMPLETED
Conditions: Lymphoma, AIDS-related|Lymphoma, Large B-Cell, Diffuse
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: Filgrastim|DRUG: EPOCH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HuMax-CD20 i(Ofatumumab) n Follicular Lymphoma (FL) Patients Refractory to Rituximab
Status: COMPLETED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Ofatumumab|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Warthin Tumor of Parotid Gland.
Status: UNKNOWN
Conditions: Warthin's Tumor of Parotid Gland
Interventions: PROCEDURE: Ultrasound-Guided Ethanol Sclerotherapy (UGES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Database Evaluating Outcomes of Using Carbetocin as the Primary Uterotonic Following Cesarean Delivery
Status: COMPLETED
Conditions: Carbetocin|Cesarean Section Complications|Uterotonics|Uterine Atony With Hemorrhage
Interventions: DRUG: Carbetocin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Comparison of the Stain Removal Efficacy of Two Air Polishing Powders
Status: COMPLETED
Conditions: Stain Removal Efficacy
Interventions: DRUG: sodium bicarbonate powders with grain size 65 µm|DRUG: sodium bicarbonate powders with grain size 40 µm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DIETARY_SUPPLEMENT: AXA1665|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating the Efficacy of Temperature-controlled Radiofrequency (TRF) in the Treatment of Vulvovaginal Atrophy.
Status: UNKNOWN
Conditions: Postmenopausal Vulvovaginal Atrophy
Interventions: DEVICE: high frequency fulguration equipment|DRUG: promestriene vaginal soft capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of the 3rd Booster Dose Using the High or Medium Dose of Inactivated Vaccine in Healthy Adults in in Hong Kong
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: COVID-19 Vaccine (Vero Cell), Inactivated (Medium-dose)|BIOLOGICAL: COVID-19 Vaccine (Vero Cell), Inactivated (High-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Does Resistance Training Protocol Change Micromorphology in Achilles Tendinopathy?
Status: ACTIVE_NOT_RECRUITING
Conditions: Achilles Tendinopathy
Interventions: OTHER: Achilles Tendon Loading Exercise Protocol According to Silbernagel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: KTP Green Light Prostatectomy Compared With TUR-P in High Risk Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: BPH (Benign Prostatic Hyperplasia)
Interventions: PROCEDURE: KTP laser|PROCEDURE: TUR-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Progressive Relaxation and Breathing Exercises Accompanied by Music on the Stress Levels of Nursing Students and Their Bio-psycho-social Responses
Status: COMPLETED
Conditions: Stress|Stress, Physiological
Interventions: BEHAVIORAL: Progressive Muscle Relaxation and Breathing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare QL1207 to Eylea® in Subjects With Wet Age-related Macular Degeneration (wAMD)
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Cancers in Low Resource Countries
Status: UNKNOWN
Conditions: Breast Neoplasms|Uterine Cervical Neoplasms|Ovarian Neoplasms|Endometrial Neoplasms
Interventions: PROCEDURE: Breast Cancer Screening and Diagnosis|PROCEDURE: Cervical Cancer Screening and Diagnosis|PROCEDURE: Ovarian Cancer Screening and Diagnosis|PROCEDURE: Endometrial Cancer Screening and Diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Venous Leg Ulcers
Status: COMPLETED
Conditions: Ulcers
Interventions: DRUG: MEBO Wound Ointment (MEBO)|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: bTAE-HAIC Combined With Lenvatinib and Sintilimab for Infiltrative Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Liver Diseases|Hepatocellular Carcinoma|Immunotherapy|Lenvatinib|Sintilimab
Interventions: PROCEDURE: bTAE-HAIC|DRUG: Lenvatinib|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients
Status: COMPLETED
Conditions: Critical Illness|Sepsis|Septic Shock|Ventilator Associated Pneumonia
Interventions: DRUG: SDD Oral Paste|DRUG: SDD Gastric Suspension|DRUG: Intravenous Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal Therapy
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Malignant Neoplasm in the Lymph Nodes|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8
Interventions: DRUG: Avelumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Peposertib|OTHER: Questionnaire Administration|RADIATION: Radium Ra 223 Dichloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of N-Acetylcystein on Quality of Life and Air Trapping During Rest and After Exercise
Status: UNKNOWN
Conditions: Quality of Life|Exercise
Interventions: DRUG: Effect on small airways (N-Acetylcystein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-assisted Therapy for Phantom Limb Pain
Status: RECRUITING
Conditions: Phantom Limb Pain
Interventions: DRUG: Psilocybin|DRUG: Placebo Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Patterns, Causes, and Control of Disease in Patients With Lung Cancer in the North Trent (England) Region
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: GENETIC: genetic linkage analysis|GENETIC: loss of heterozygosity analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: biologic sample preservation procedure|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: evaluation of cancer risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Personalized Ultrasonic Brain Stimulation for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Episode
Interventions: DEVICE: Diadem prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pentoxifylline After Cardiac Surgery
Status: COMPLETED
Conditions: Oxidative Stress|AKI|Inflammation
Interventions: OTHER: Pentoxifylline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Control After Minimally Invasive Coronary Artery Bypass Grafting
Status: TERMINATED
Conditions: Postoperative Pain|Medication Side Effects|Narcotic Requirement
Interventions: DRUG: IV acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Merkel Cell Carcinoma|Basal Cell Carcinoma|Melanoma
Interventions: BIOLOGICAL: RP1, intra-tumoral injection, oncolytic virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Effects of Different Therapies for the Treatment of Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Acupuncture|DEVICE: Aerobic exercise|DEVICE: Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab Combined With Rivoceranib Mesylate Versus Investigator's Choice of Regimen in Treatment of Patients With Advanced Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Advanced Hepatocellular Carcinoma (HCC)
Interventions: DRUG: camrelizumab；Rivoceranib|DRUG: Rivoceranib|DRUG: Sorafenib|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Localized and Disseminated Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma
Interventions: DRUG: Zoledronic acid|DRUG: Busulfan|DRUG: Treosulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4-week Seaweed Supplementation on Menopause Symptoms and Psychological Wellbeing
Status: COMPLETED
Conditions: Menopausal Syndrome|Menopausal Depression
Interventions: DIETARY_SUPPLEMENT: 500mg seaweed|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study of Nab-paclitaxel Combined With Toripalimab in Local Advanced or Metastatic G/GEJ Carcinoma
Status: UNKNOWN
Conditions: Gastric Carcinoma
Interventions: DRUG: Albumin-Bound Paclitaxel|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Cure Rate of Peg-IFNα-2b Combined With TAF in HBeAg Negative CHB Patients
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: PEG IFN α-2b; TAF|BIOLOGICAL: PEG IFN α-2b; TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Standard Guarded Trabeculectomy|DRUG: Mitomycin C|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Wall Thickness in Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: Noncontrast echocardiography|PROCEDURE: Contrast Echocardiography|PROCEDURE: Cardiac magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
Status: RECRUITING
Conditions: AMD|nAMD|Wet Age-related Macular Degeneration|wAMD|WetAMD|CNV
Interventions: GENETIC: RGX-314 Dose 1|GENETIC: RGX-314 Dose 2|BIOLOGICAL: Aflibercept (EYLEA®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Therapy for Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Umbilical Cord Blood Infusion|OTHER: Placebo Umbilical Cord Blood|OTHER: Active Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol-Enhanced Assessment of Ketamine for Chronic Pain and Depression
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Depression
Interventions: DRUG: Ketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure|Left Bundle-Branch Block|Ischemic Cardiomyopathy|Non-ischemic Dilated Cardiomyopathy|Left Ventricular Dysfunction|Left Ventricular Dyssynchrony|Left Ventricle Remodeling
Interventions: DEVICE: Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Biventricular Pacing|DEVICE: Implantation of Cardioverter-defibrillator with a Resynchronization Function Using Left Bundle Branch Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)
Status: COMPLETED
Conditions: Suicide|Suicide, Attempted
Interventions: BEHAVIORAL: Safety Planning - Military (SAFE MIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Has Not Responded to Platinum- Based Chemotherapy
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: ALT-100 mAb|DRUG: ALT-100 (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lorazepam Effects on Neuroimaging Measures
Status: WITHDRAWN
Conditions: Lorazepam|Neuroimaging
Interventions: DRUG: Lorazepam 1Mg Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: DRUG: Atorvastatin 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decreasing Rates of Intraurethral Catheterization Postoperatively in Spine Surgery
Status: COMPLETED
Conditions: Post-operative Urinary Retention
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: NGM282
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EVOLUTION: 177Lu-PSMA Therapy Versus 177Lu-PSMA in Combination With Ipilimumab and Nivolumab for Men With mCRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Genital Neoplasms, Male|Urogenital Neoplasms|Prostate Cancer|Neoplasms by Site|Neoplasms|Prostatic Disease
Interventions: DRUG: 177Lu-PSMA-617|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966)
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Fluticasone Furoate Nasal Spray on Spring Allergy Eye Symptoms
Status: COMPLETED
Conditions: Allergic Conjunctivitis to Tree Pollen or Grass Pollen
Interventions: DRUG: Fluticasone furoate nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lipinova on Inflammatory and Proresolving Lipid Mediator Profiles After Orthopedic Surgery
Status: UNKNOWN
Conditions: Inflammation|Surgery
Interventions: DIETARY_SUPPLEMENT: low dose Lipinova (30 mL daily)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: high dose Lipinova (60mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open Clinical Trial of CBT-based Multiprofessional Rehabilitation for Exhaustion Disorder
Status: COMPLETED
Conditions: Exhaustion; Syndrome|Burnout, Professional|Burnout Syndrome|Adjustment Disorders
Interventions: BEHAVIORAL: Multi-professional CBT-rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: Abiraterone acetate|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
Status: RECRUITING
Conditions: Fentanyl|Platelet Reactivity
Interventions: DRUG: Morphine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Daclatasvir From Daclatasvir Zeta 60 mg Film Coated Tablets (Zeta Pharm Pharmaceutical Industries, Egypt) and Clatazev 60 mg Tablets (Bristol-Myers Squibb Pharma, UK)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Daclatasvir Zeta|DRUG: Clatazev
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children
Status: COMPLETED
Conditions: Persistent Pulmonary Hypertension of the Newborn
Interventions: DRUG: Sildenafil|DRUG: Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence, Incidence and Characteristics of NAFLD/NASH in Type 1 Diabetes Mellitus
Status: RECRUITING
Conditions: NAFLD|Type 1 Diabetes|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: ultrasound|DIAGNOSTIC_TEST: elastography|DIAGNOSTIC_TEST: controlled attenuation parameter (CAP)|DIAGNOSTIC_TEST: FLI|DIAGNOSTIC_TEST: FIB-4|DIAGNOSTIC_TEST: NFS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hashimoto Disease|Psoriasis
Interventions: COMBINATION_PRODUCT: Nutraceutical Combination Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Skeletal Health in Bariatric Surgery Patients
Status: COMPLETED
Conditions: Bariatric Surgery|Osteoporosis|Fractures, Bone|Roux En-Y Gastric Bypass|Sleeve Gastrectomy|Menopause|Premenopause
Interventions: PROCEDURE: Roux en Y Gastric Bypass Pre-menopausal|PROCEDURE: Roux en Y Gastric Bypass Post-menopausal|PROCEDURE: Sleeve Gastrectomy Pre-menopausal|PROCEDURE: Sleeve Gastrectomy Post-menopausal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maggot Therapy for Wound Debridement
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: OTHER: application of wound dressing made of bio-bags (vitapads) containing maggots|OTHER: application of classical hydrogel/alginate wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Trial of Effectiveness of a Backward Walking Program in Patients Recovering From Abdominal Aorta Surgery
Status: COMPLETED
Conditions: Abdominal Surgery
Interventions: PROCEDURE: forward walking|PROCEDURE: backward walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot|Diabetic Foot Ulcer|Foot Ulcer|Chronic Foot Ulcer
Interventions: DEVICE: Symphony™ plus Off-loading|DEVICE: Wound Dressing comprising of calcium alginate Fibracol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Immersive Virtual Reality Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Nurse's Role|COVID-19 Pandemic|Mental Stress
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction by Therapeutic VR|BEHAVIORAL: Mindfulness-based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.
Status: UNKNOWN
Conditions: Open Angle Glaucoma
Interventions: DRUG: Cosopt|DRUG: Xalatan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Arthroscopic Superior Capsular Reconstruction With Fascia Lata Autograft - Survivorship of the Autograft Analysis
Status: COMPLETED
Conditions: Graft Failure|Donor Site Complication|Rotator Cuff Tear
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging of the shoulder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Efficacy and Safety of Lenalidomide Plus Low-dose Dexamethasone Versus Melphalan, Prednisone, Thalidomide in Patients With Previously Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide and low-dose dexamethasone|DRUG: Lenalidomide plus low-dose dexamethasone given for 18 four-week cycles|DRUG: Melphalan, Prednisone and Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Single Low-dose Primaquine for the Clearance of Gametocytes
Status: COMPLETED
Conditions: Plasmodium Falciparum
Interventions: DRUG: Primaquine (For artemether-lumefantrine+primaquine arm)|DRUG: Placebo (For artemether-lumefantrine arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of PERMEAPROTECT on the Quality of Life of Patients With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: PERMEAPROTECT|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medication Adherence With Telehealthcare Medication Therapy Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Uncontrolled Asthma|Young Adults
Interventions: BEHAVIORAL: Medication Therapy Management (MTM) Video Telehealthcare|BEHAVIORAL: Electronic Adherence Self-Management (EAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-dose CD20 Monoclonal Antibody Injection in Preemptive Treatment of PTLD in Patients With EBV-HLH/CAEBV
Status: UNKNOWN
Conditions: PTLD|CAEBV|HLH
Interventions: DRUG: low-dose CD20 monoclonal antibody injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Biomarkers of Cardiovascular Risk
Status: TERMINATED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants
Status: SUSPENDED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: JNJ-64281802 High dose|DRUG: JNJ-64281802 Medium dose|DRUG: JNJ-64281802 Low dose|DRUG: JNJ-64281802 Dosing Regimen X|DRUG: JNJ-64281802 Dosing Regimen Y|DRUG: JNJ-64281802 Dosing Regimen Z
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER