pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prevention of Gastric Ulcer Bleeding by Using "Computer-alert" in General Practice
Status: UNKNOWN
Conditions: Bleeding Peptic Ulcer
Interventions: OTHER: Computer-alert|DEVICE: A computer alerts which pops up when the GP presribes NSAID/ASA to a patient with risk-factors|DEVICE: Computer-alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications
Status: RECRUITING
Conditions: Hip Arthropathy|Knee Arthropathy|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration
Status: UNKNOWN
Conditions: Cancer Pain
Interventions: DRUG: Hydromorphone Hydrochloride Injection|DRUG: Hydromorphone Hydrochloride Injection|DRUG: Morphine Sulfate Sustained-release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention With Long-chain n-3 Polyunsaturated Fatty Acids From Microalgae Oil in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: long-chain n-3 PUFA|DIETARY_SUPPLEMENT: sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Fluorescence Imaging With Indocyanine Green
Status: COMPLETED
Conditions: Solitary Pulmonary Nodules
Interventions: DEVICE: near infrared fluorescence imaging (NIFI)|DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cerebrovascular Disease: Quality of Life (CODE: QoL)
Status: RECRUITING
Conditions: Quality of Life|Stroke, Acute|Sexual Behavior|Stress|Cortisol Excess|Incontinence, Urinary|Caregiver Burden|Transient Ischemic Attack|Intracerebral Hemorrhage|Cerebrovascular Disorders
Interventions: DIAGNOSTIC_TEST: questionnaire, hair samples, blood samples, clinical exam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Function and Fit of Standard and Gender-Specific CR High-Flex Total Knee Prostheses
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Standard CR-Flex total knee|DEVICE: Gender specific CR-Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Bioavailability Study of SYR-322MET
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Alogliptin|DRUG: Metformin Hydrochloride|DRUG: SYR-322MET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources
Status: RECRUITING
Conditions: PreDiabetes|Diabetes Mellitus, Type 2|Overweight and Obesity
Interventions: OTHER: Keto-SAT|OTHER: Keto-CAN|OTHER: LFD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of a Single Spinal Manipulation on Cardiovascular Autonomic Activity
Status: COMPLETED
Conditions: Manipulation, Spinal
Interventions: OTHER: High velocity low amplitude manipulation|OTHER: Sham manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Safety, Reactogenicity and Immune Response of the Repeat Vaccination Against RSV When Given to Female Participants of 18-49 Years of Age During Their Subsequent Uncomplicated Pregnancy
Status: WITHDRAWN
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV MAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cement flooRs AnD chiLd hEalth (CRADLE)
Status: RECRUITING
Conditions: Ascaris Lumbricoides Infection|Necator Americanus Infection|Trichuris Trichiura; Infection|Diarrhea
Interventions: OTHER: Concrete household floor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label Study of the Effects of Acetyl-L-Carnitine on Cardiovascular Outcomes in Friedreich's Ataxia
Status: UNKNOWN
Conditions: Friedreich's Ataxia
Interventions: DRUG: Acetyl-L-Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention With a GABA Supplement in Prediabetics
Status: COMPLETED
Conditions: Prediabetes|Hypertension
Interventions: DIETARY_SUPPLEMENT: GABA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of ABO809 in Healthy Participants
Status: COMPLETED
Conditions: Cryptosporidium Infection, Cryptosporidiosis
Interventions: BIOLOGICAL: Cryptosporidium parvum oocysts (ABO809)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atrial Fibrillation After Catheter Versus Thoracoscopic Ablation Using Patient Activated Implantable Loop Recorders: The ACTUAL Study
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Implantation of implantable loop recorder|PROCEDURE: Percutaneous ablation of atrial fibrillation|PROCEDURE: Surgical ablation of atrial fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intrafetal Digoxin as an Adjuvant for Dilation and Evacuation at 20 to 24 Weeks' Gestation
Status: COMPLETED
Conditions: Abortion
Interventions: DRUG: Digoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Periodized Resistance Training and High Intensity Training on BMI and QOL in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Periodized resistance training|OTHER: High intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Single-agent Inavolisib and Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers
Status: RECRUITING
Conditions: PIK3CA-Mutated Cancers
Interventions: DRUG: Inavolisib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers
Status: TERMINATED
Conditions: Metastatic and Advanced Solid Tumors
Interventions: DRUG: NIZ985|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Loading Dose Magnesium Sulphate With Prichard Regimen in the Management of Severe Preeclampsia and Eclampsia.
Status: COMPLETED
Conditions: Severe Pre-eclampsia|Eclampsia
Interventions: DRUG: Use of magnesium sulfate to prevent and stop fits in pre-eclampsia and Eclampsia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Metronomic CP and JX-594 in Patients With Advanced Breast Cancer and Advanced Soft-tissue Sarcoma (METROmaJX)
Status: RECRUITING
Conditions: Solid Tumors|Soft-tissue Sarcoma|Breast Cancer
Interventions: DRUG: Cyclophosphamide and JX-594 dose escalation|DRUG: Cyclophosphamide and JX-594|DRUG: Cyclophosphamide|DRUG: Avelumab and JX-594 and Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Pharmacodynamics After Multiple Oral Doses of Dabigatran Etexilate Capsule in Healthy Japanese and Caucasian Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran high dose|DRUG: Dabigatran low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Multi-center Study of Anti-PD-1 During Lymphopenic State After HDT/ASCT for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous Stem Cell Transplant|DRUG: Melphalan|DRUG: Lenalidomide|DRUG: MK-3475
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Enteral Iron in Infants Less Than 1301 Grams
Status: COMPLETED
Conditions: Iron Deficiency|Anemia of Prematurity
Interventions: DRUG: Oral administration of ferrous sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Single Path Versus Double Path PECS I and II Blocks as an Efficient Analgesic Choice in Female Breast Surgeries.
Status: COMPLETED
Conditions: Analgesia
Interventions: OTHER: single needle path PECS I and II block group|OTHER: double needle path PECS I and II block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of FT218 in Subjects With Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy|Cataplexy|Excessive Daytime Somnolence|Sleep Disorder|Sleep Disturbance|Sleep Wake Disorders
Interventions: DRUG: FT218
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Inhibition by Aspirin, Acetaminophen and NSAID
Status: COMPLETED
Conditions: Hemostasis
Interventions: DRUG: Acetylsalicylic acid, acetaminophen, diclofenac, naproxen, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Emu Oil vs. Placebo for Vulvar Pain in Women.
Status: TERMINATED
Conditions: Vulvodynia|Vestibulodynia
Interventions: OTHER: Emu Oil|OTHER: Inert oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Exercise in Children With Malignant Hemopathies
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|Leukemia, B-cell|Leukemia, T Cell|Lymphoma, Hodgkin|Lymphoma, Non-Hodgkin|Drepanocytosis|Thalassemia Major|Adrenoleukodystrophy
Interventions: OTHER: Sport Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: ALS
Interventions: BIOLOGICAL: TCD601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Live After an Epithelial Ovarian Cancer: Multidisciplinary Assessment of Effects and Long-term Remission in Patients Needs.
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: OTHER: Gynecological consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Topical Lidocaine to Reduce Pain in Preterm Infants Receiving Nasal CPAP Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Other Preterm Infants
Interventions: DRUG: Lidocaine 2% Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate and Metformin in Rheumatoid Arthritis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Metformin treatment|OTHER: Placebo|DRUG: Methotrexate treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Interferon And CCI-779 In Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Kidney Neoplasms
Interventions: DRUG: Interferon Alfa|DRUG: CCI-779|DRUG: Interferon Alfa and CCI-779
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Ependymoma|Brain Ependymoma|Cellular Ependymoma|Clear Cell Ependymoma|Ependymoma|Papillary Ependymoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Carboplatin|DRUG: Cisplatin|OTHER: Clinical Observation|DRUG: Cyclophosphamide|DRUG: Etoposide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Mesna|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating 18F-FDG PET/CT With Liver SUVmax-based Criteria for Prognosis of Patients With Peripheral T-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, T-Cell, Peripheral
Interventions: DEVICE: 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: CT-P13|DRUG: Remicade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia
Status: RECRUITING
Conditions: Post Operative Pain, Acute
Interventions: PROCEDURE: thoracic paravertebal block|PROCEDURE: serratus anterior muscle block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Retapamulin for Reducing MRSA Nasal Carriage
Status: COMPLETED
Conditions: Methicillin-Resistant Staphylococcus Aureus
Interventions: DRUG: Retapamulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A DRUG-DRUG INTERACTION STUDY BETWEEN PF-06650833 AND PF-06651600 FOLLOWING MULTIPLE DOSES IN HEALTHY PARTICIPANTS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06650833 alone|DRUG: PF-06651600 alone|DRUG: PF-06650833 together with PF-06651600
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vortioxetine add-on Treatment Improves the Symptoms in Patients With Bipolar Depression
Status: UNKNOWN
Conditions: Bipolar Disorder Depression
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early rhBNP on Myocardial Work in Patients With STEMI
Status: UNKNOWN
Conditions: ST-Segment Elevated Myocardial Infarction
Interventions: DRUG: rhBNP|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
Status: RECRUITING
Conditions: Other Specified Disorders of Kidney and Ureter|Benign Neoplasm of Ureter|Calculus of Kidney and Ureter|Ureter Cancer|Ureteric Reflux|Congenital Ureteric Anomaly|Benign Renal Neoplasm|Renal Cancer
Interventions: DRUG: spinal analgesia with morphine and bupivacaine|DRUG: lidocaine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of a Modified-release Tacrolimus Based Immunosuppression Regimen in Stable Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus Modified Release (MR)|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of AirGLovE in Difficult Venous Access
Status: COMPLETED
Conditions: Cancer
Interventions: DEVICE: Airglove (TM)|DEVICE: Warm-water Immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Pain, Migraine
Interventions: DRUG: Aspirin, acetaminophen and caffeine|DRUG: Sumatriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589
Status: COMPLETED
Conditions: Cancer Patients With Advanced Solid Tumors Including Lymphoma or Chronic Hematological Malignancies
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Treatment of Sacituzumab-govitecan for Patients With Metastatic Esophagogastric Adenocarcinoma
Status: RECRUITING
Conditions: Esophagogastric Adenocarcinoma
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Carboplatin in Treating Patients With Relapsed Stage III or Stage IV Ovarian Epithelial or Primary Peritoneal Cavity Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: carboplatin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Wear of a Steel and a Teflon Insulin Infusion Set
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: YpsoPump Orbit soft|DEVICE: YpsoPump Orbit micro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a One-a-Day L. Reuteri NCIMB 30242 Probiotic Supplement Capsule
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: One-a-Day L. reuteri NCIMB 30242 supplement capsule|DIETARY_SUPPLEMENT: One-a-Day placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI346#CIBI346Y002#
Status: UNKNOWN
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: IBI346
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab in Combination With GM.CD40L Vaccine in Adenocarcinoma of the Lung
Status: WITHDRAWN
Conditions: Lung Cancer|Adenocarcinoma of the Lung
Interventions: DRUG: Nivolumab|BIOLOGICAL: GM.CD40L Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Iron in Association With Tranexamic Acid for Hip Fracture
Status: UNKNOWN
Conditions: Hip Fracture|Anemia
Interventions: DRUG: tranexamic acid (Exacyl®)|DRUG: intravenous iron (Ferroven®)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Noninvasive Brain Stimulation for pAD
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease - MCI
Interventions: DEVICE: 20 Hz rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Head and Neck Positions for Endotracheal Intubation Using a Videolaryngoscope
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: PROCEDURE: endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Zimberelimab Plus Lenvatinib After Progression on Prior Immune Checkpoint Inhibitors for Advanced Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Cervical Carcinoma
Interventions: DRUG: Zimberelimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Metabolic Syndrome|Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Digital wearable and AI-human symbiotic lifestyle intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Compression Stockings on Cerebral Desaturation Events in Obese Patients Undergoing Shoulder Arthroscopy in the Beach Chair
Status: COMPLETED
Conditions: Shoulder Arthoscopy|Beach Chair Position|Cerebral Desaturation Events|Obese
Interventions: OTHER: Thigh High Compression Stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of MCDG Oil on Postprandial Lipid Metabolism
Status: COMPLETED
Conditions: Hyperlipidemias|Triglycerides High
Interventions: DIETARY_SUPPLEMENT: LCT oil|DIETARY_SUPPLEMENT: MCDG oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of Raw Corn Starch on Patients With Insulinoma
Status: UNKNOWN
Conditions: Hyperinsulinemic Hypoglycemia|Insulinoma|Raw Corn Starch
Interventions: OTHER: low GI diet with regular supplementation of raw corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Enzalutamide and Flutamide in Patients With Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Flutamide|OTHER: Androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Blood and Urine Drug Levels of Fostamatinib Disodium (FosD) in Healthy Japanese and White Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FosD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human BCMA Targeted T Cells Injection Therapy for BCMA-positive Relapsed/Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Human BCMA targeted T Cells Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Results of Treatment by Gamma Nail Versus Dynamic Hip Screw for Unstable Intertrochanteric Hip Fractures
Status: UNKNOWN
Conditions: Intertrochanteric Fractures of the Hip
Interventions: DEVICE: gamma nail stryker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Program of Physician Supervision to Improve the Quality of Patient Referrals From Nurse Practitioners and Physician Assistants
Status: TERMINATED
Conditions: Complex Patients
Interventions: BEHAVIORAL: Consultations between NPs and PAs and their supervising physicians|BEHAVIORAL: versus NPs and PAs who are not required to discuss patient referrals (control group).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Safety and Efficacy of DCVAC/LuCa (Immunotherapy of Lung Cancer) in Patients With Metastatic Lung Cancer
Status: COMPLETED
Conditions: Stage IV Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: DCVAC add on to SOC|BIOLOGICAL: DCVAC and immune enhancers add on to SOC|OTHER: Standard of Care Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Xpert Diagnosis of TB Using Tracheal Aspirates From Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Tuberculosis
Interventions: OTHER: Xpert|OTHER: Smear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of DR-2011 to a Progesterone Vaginal Gel for Luteal Phase Replacement
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: DR-2011|DRUG: Progesterone 8% Vaginal Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Administration of Vitamin C in Wrist Fractures
Status: COMPLETED
Conditions: RSD (Reflex Sympathetic Dystrophy)|Algodystrophy|CRPS Type I
Interventions: DRUG: ascorbic acid (vitamin C) versus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Nitric Oxide Releasing Solution to Treat and Prevent Exacerbation of Mild COVID-19 Infection
Status: WITHDRAWN
Conditions: SARS-CoV Infection
Interventions: DRUG: Nitric Oxide-Releasing Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proximal Femur Locking Compression Plates Versus Trochanteric Nails
Status: COMPLETED
Conditions: Reverse Oblique Intertrochanteric Fractures|Reverse Oblique Subtrochanteric Fractures
Interventions: DEVICE: Proximal femur locking plate|DEVICE: Intertrochanteric nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axitinib in Metastatic Renal Cell Carcinoma Patients With Favorable Prognostic Factors
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Clear Cell Renal Cell Carcinoma
Interventions: DRUG: axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: HO/03/03 10µg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digestion of Foods Consumed in Africa
Status: COMPLETED
Conditions: Obesity and Other Hyperalimentation
Interventions: OTHER: Rice|OTHER: Potato|OTHER: Pasta|OTHER: Sorghum thick porridge|OTHER: Millet thick porridge|OTHER: Millet couscous|OTHER: Millet thin porridge|OTHER: Millet thin monikuru porridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Static Stretching on Postural Sway and Plantar Pressures
Status: COMPLETED
Conditions: Muscle Stretching Exercise; Postural Balance; Stabilometry; Platform
Interventions: OTHER: Intermittent stretching protocol|OTHER: Continuous stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flibanserin on the Pre- and Post-menopausal Female Brain
Status: TERMINATED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Flibanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of a Walking Assist Robot on Gait Function and Brain Activity in Stroke Patients and Elderly Adults
Status: COMPLETED
Conditions: Stroke|Healthy
Interventions: PROCEDURE: Gait, sit-to-stand movement, stair climbing and treadmill gait|PROCEDURE: Sit-to-stand movement and treadmill gait|DEVICE: gait enhancing mechatronic system (GEMS)|DEVICE: treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoid Syndrome|Carcinoid|Carcinoid Tumor|Carcinoid Tumor of Ileum|Carcinoid Tumor of Cecum|Carcinoid Syndrome Diarrhea|Carcinoid Intestine Tumor|Carcinoid Tumor of Liver|Carcinoid Tumor of Pancreas
Interventions: DRUG: Randomized: 40 mg Paltusotine|DRUG: Randomized: 80 mg Paltusotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mgt of Chronic Subdural Hematoma Using Dexamethasone
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Dexamethasone|PROCEDURE: Any surgical intervention aim at treating chronic subdural hematoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Single Incision Laparoscopic Appendectomy and Three Port Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Acute Appendicitis
Interventions: PROCEDURE: SILS appendectomy|PROCEDURE: Three port laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Adoption of the TelTex4BP Intervention Among Adults With Hypertension in Nepal
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Medication Adherence|Blood Pressure|Cardiovascular Diseases
Interventions: BEHAVIORAL: Phone call and text Messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fed Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Controlled-Release Oxycodone Hydrochloride 40 mg|DRUG: OxyContin® 40 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Intermittent insulin therapy|DRUG: Continuous metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Veinlite Reduce Complications of Peripheral Intravenous Catheter Placement in Children
Status: COMPLETED
Conditions: Catheterization|Pain|Complication
Interventions: DEVICE: Veinlite|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Prospective Comparison of the Outcome of Toric Implantable Contact Lens (TICL) and Q-LASIK for the Correction of Myopia With Astigmatism
Status: UNKNOWN
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: the implantation of toric implantable collamer lens|PROCEDURE: customized laser-assisted in situ keratomileusis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Anti-tumor Activity of SYHA1801 Monotherapy in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Drug: SYHA1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multicenter Clinical Trial With Nivolumab (BMS-936558) Monotherapy in Subjects With Advanced or Metastatic Squamous Cell (Sq) Non-Small Cell Lung Cancer (NSCLC) Who Have Received at Least One Prior Systemic Regimen for the Treatment of Stage IIIb/IV SqNSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Status: RECRUITING
Conditions: Melanoma|Lymphoma|Solid Tumor|Classical Hodgkin Lymphoma|Microsatellite-instability-high Solid Tumor
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myofascial Induction in Breast Cancer Survivors
Status: COMPLETED
Conditions: Pain|Breast Cancer
Interventions: BEHAVIORAL: Myofascial Induction|DEVICE: Unplugged pulsed shortwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The SERENITY Study: Online Mindfulness-Based Cancer Recovery for Patients With Gynecological Cancer
Status: COMPLETED
Conditions: Gynecologic Cancer
Interventions: BEHAVIORAL: Online Mindfulness-Based Cancer Recovery (MBCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Different Oral Doses of BAY94-8862 in Japanese Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy (ARTS-DN Japan)
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: BAY94-8862|DRUG: Placebo|DRUG: BAY 94-8862|DRUG: BAY 94-8862
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EARLY IFNB-1a and Simvastatin Combination Therapy in Clinically Isolated Syndrome Suggestive of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Avonex/Zocor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide for Lenalidomide for Relapsed or Refractory Multiple Myeloma Patients
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: POM|DRUG: Steroids|DRUG: PLD|DRUG: CFZ|DRUG: BTZ|DRUG: CLA|DRUG: CY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Risk-Adapted and MRD-Driven Strategy for Untreated Fit Patients With Intermediate Risk Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Intermediate Risk Chronic Lymphocytic Leukemia|Fit Patients|Risk-Adapted and MRD-Driven Strategy
Interventions: DRUG: venetoclax and ibrutinib (I+VEN)|DRUG: FCR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes
Status: COMPLETED
Conditions: End Stage Renal Disease|Depression|Anxiety|Major Depressive Disorder|Generalized Anxiety Disorder|Compliance, Patient|Compliance, Medication|Mood|Pain|Energy Supply; Deficiency|Quality of Life|Blood Pressure|Heart Rate Fast
Interventions: BEHAVIORAL: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine or Observation for Patients With pT1N+M0 or pT2-3N0M0 Gastric Adenocarcinoma Undergoing R0 Resection
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F- Fluorothymidine to Evaluate Treatment Response in Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: PROCEDURE: Biopsy|DIAGNOSTIC_TEST: fluorodeoxyglucose F 18 Positron Emission Tomography and computed tomography|OTHER: [3'-deoxy-3'-[F-18] fluorothymidine|PROCEDURE: computed tomography|PROCEDURE: fine-needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multi-Center Study of Reading Rehabilitation in Macular Disease
Status: COMPLETED
Conditions: Age Related Maculopathy|Retinal Degeneration
Interventions: BEHAVIORAL: Module 1: Visual Awareness and Eccentric Viewing|BEHAVIORAL: Module 2: Control of Reading Eye Movements|BEHAVIORAL: Module 3: Reading Practice with RSVP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Ovarian Cancer|Recurrent Uterine Cancer|Metastatic Cancer|Advanced Cancer
Interventions: DRUG: RP-6306|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
Status: RECRUITING
Conditions: Cutaneous T-cell Lymphoma|Sezary Syndrome|Mycosis Fungoides|Eczema|Atopic Dermatitis
Interventions: OTHER: Blood draw, skin biopsy or urine collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic Cholangiocarcinoma
Status: WITHDRAWN
Conditions: Non-Resectable Cholangiocarcinoma|Recurrent Cholangiocarcinoma|Stage III Extrahepatic Bile Duct Cancer|Stage III Intrahepatic Cholangiocarcinoma|Stage IIIA Hilar Cholangiocarcinoma|Stage IIIB Hilar Cholangiocarcinoma|Stage IVA Extrahepatic Bile Duct Cancer|Stage IVA Hilar Cholangiocarcinoma|Stage IVA Intrahepatic Cholangiocarcinoma|Stage IVB Extrahepatic Bile Duct Cancer|Stage IVB Hilar Cholangiocarcinoma|Stage IVB Intrahepatic Cholangiocarcinoma|Unresectable Extrahepatic Bile Duct Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ricolinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Human Microbiota Transplantation for Overweight and Obese Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Overweight and Obesity
Interventions: BIOLOGICAL: Fecal microbiota transplant (FMT)|OTHER: normal saline and glycerin/food coloring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Duloxetine for Post Laparoscopic Shoulder Pain
Status: COMPLETED
Conditions: Post Laparoscopic Shoulder Pain
Interventions: DRUG: Duloxetine 60mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer
Interventions: DRUG: BNT323/DB-1303|DRUG: Doxorubicin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness/Meditation on Post-operative Pain and Opioid Consumption
Status: TERMINATED
Conditions: Rotator Cuff Tears
Interventions: OTHER: In addition to standard post-op medication patient will have access to the head space meditation application.|OTHER: Patients will take standard post-op pain medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of the Microbiota-gut-brain Axis in Brain Development and Mental Health
Status: UNKNOWN
Conditions: Gamma-Aminobutyric Acid|Anxiety|Glutamate|Emotion Regulation Abilities
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharides|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroplasticity Technology for Attention-deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Adaptive Inhibitory Control Training|BEHAVIORAL: Non-adaptive Inhibitory Control Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systems Aligning for Equity (SAFE) Spaces
Status: RECRUITING
Conditions: Suicide|Mental Disorder|Mental Health|Burnout, Professional|Self Harm
Interventions: BEHAVIORAL: SAFE Spaces training and coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects
Status: COMPLETED
Conditions: Mycoses
Interventions: DRUG: micafungin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Examining The Effect Of Wrist Joint Haematoma Washout As An Adjunct Procedure To Plating Of The Distal Radius In Fractures Of The Distal Radius Involving The Wrist Joint
Status: WITHDRAWN
Conditions: Radius Fracture Distal
Interventions: PROCEDURE: Wrist joint haematoma washout|PROCEDURE: Volar locking plate insertion of the distal radius
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gastroesophageal Varices in Cavernoma
Status: UNKNOWN
Conditions: Gastroesophageal Varices|Myeloproliferative Neoplasm|Portal Caver Cavernoma|Portal Hypertension
Interventions: DIAGNOSTIC_TEST: JAK2 mutation test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Radspherin® in Recurrent Ovarian Cancer Subjects With Peritoneal Carcinomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Carcinomatosis|Ovarian Cancer
Interventions: DRUG: Radspherin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Universal Eye Drop Adherence Monitor to Measure and Improve Adherence to Ocular Medications
Status: COMPLETED
Conditions: Medication Adherence|Glaucoma
Interventions: DEVICE: Devers Drop Device (D3) app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC