pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Immunogenicity of CJ-40010 in Healthy Subjects
Status: UNKNOWN
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: CJ-40010 EV71 vaccine A dose|BIOLOGICAL: CJ-40010 EV71 vaccine B dose|BIOLOGICAL: CJ-40010 CVA16 vaccine C dose|BIOLOGICAL: CJ-40010 CVA16 vaccine D dose|BIOLOGICAL: CJ-40010 Bivalent vaccine E dose|BIOLOGICAL: CJ-40010 Bivalent vaccine high dose|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Preoperative Serum Thyroglobulin Level to Differentiate Between Different Thyroid Nodules
Status: NOT_YET_RECRUITING
Conditions: Level of Thyrogobulin in Different Thyroid Nodules
Interventions: PROCEDURE: Thyriodectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MAS-1 Adjuvanted Compared to Unadjuvanted Influenza Vaccines in the Elderly
Status: WITHDRAWN
Conditions: Influenza Vaccines|Aged
Interventions: BIOLOGICAL: MAS-1 adjuvant and influenza HA antigen|BIOLOGICAL: standard dose, inactivated trivalent influenza vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Subjective and Audiological Benefit of BONEBRIDGE (BCI602) With Two Different Fitting Strategies
Status: RECRUITING
Conditions: Bone Conduction Deafness|Quality of Life|Hearing Loss, Mixed
Interventions: PROCEDURE: Fitting of the audioprocessor with the auditory implant BCI602
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dose-confirmatory Bridging Study in Total Hip Replacement
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban (BAY59-7939)|DRUG: Rivaroxaban (BAY59-7939)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Study to Assess the Safety, Tolerability and Pharmacokinetics(PK) of PF-06865571
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06865571|DRUG: PF-06865571|DRUG: PF-06865571|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BPX-01 Minocycline Topical Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BPX-01 1% Minocycline Topical Gel|DRUG: BPX-01 2% Minocycline Topical Gel|DRUG: BPX-01 Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sweat Rate Measurement With a Sensor (Wearable) in Different Climatic Conditions With Road Cyclists.
Status: COMPLETED
Conditions: Sweat
Interventions: OTHER: Low intensity|OTHER: Low temperature|OTHER: Low Humidity|OTHER: High intensity|OTHER: High temperature|OTHER: High humidity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Binding of Foliglurax to Regions in the Brain in Healthy Participants and in Patients With Parkinson's Disease (PD)
Status: TERMINATED
Conditions: Healthy|Parkinson Disease
Interventions: DRUG: foliglurax|DRUG: foliglurax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin's B-cell Lymphoma
Interventions: BIOLOGICAL: Prizloncabtagene autoleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Knee Osteoarthritis: Intra-articular Injection of Filtered Autologous Adipose Tissue Versus Placebo
Status: RECRUITING
Conditions: Bilateral Knee Osteoarthritis|Autologous Adipose Tissue
Interventions: COMBINATION_PRODUCT: injection of Filtered Autologous Adipose Tissue|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TheraTogs Versus Reciprocal Electrical Stimulation on Children With Diplegic Cerebral Palsy: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DEVICE: 1- Reciprocal electrical stimulation|DEVICE: TheraTogs orthotic treatment|PROCEDURE: traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Anti-PD-1 Antibody Nivolumab in Combination With Dabrafenib and/or Trametinib
Status: WITHDRAWN
Conditions: Metastatic Melanoma
Interventions: DRUG: Nivolumab|DRUG: Trametinib|DRUG: Dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis for Transrectal Prostate Biopsy-Ciprofloxacin vs. Trimethoprim/Sulfamethoxazole
Status: UNKNOWN
Conditions: Prostate Infection
Interventions: DRUG: Trimethoprim/Sulfamethoxazole|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Escalation Trial Of PF-04308515 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04308515|DRUG: Placebo|DRUG: PF-04308515 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: Methadone|DRUG: Buprenorphine-Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Vi-DT Typhoid Conjugate Vaccine
Status: COMPLETED
Conditions: Typhoid
Interventions: BIOLOGICAL: Vi-DT|BIOLOGICAL: Typhim Vi®|BIOLOGICAL: VAXIGRIP®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Geriatric Intervention in Treatment of Older Patients With Cancer (PREPARE)
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer|Lung Cancer|Prostate Cancer|Bladder Cancer|Ovarian Cancer|Lymphoma
Interventions: OTHER: Geriatrician Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of CaviionTM Precaution Medical Adhesive-related Skin Injury in Tumor Patients With PICC Catherizaion
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumour
Interventions: OTHER: 3M CaviionTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BeEAM Versus CEM in Lymphoma Patients as a Conditioning Regimen Before Autologous Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: BEAM Protocol|DRUG: CEM protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability of an Ancient Grain in Patients With Non-Celiac Wheat Sensitivity
Status: RECRUITING
Conditions: Non-celiac Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: Administration of Triticum Monococcum flour|DIETARY_SUPPLEMENT: Administration of Triticum Aestivum flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Docetaxel, Prednisone, and Pasireotide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: pasireotide|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Pain Due to Propofol Injection
Status: UNKNOWN
Conditions: Pain|Intravenous Propofol Injection
Interventions: DRUG: I.V injection of 10 ml normal saline|DRUG: I.V injection with 0.25mic/kg of dexmedetomidine|DRUG: I.V injection of 0.50mic/kg of dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Analgesia for Pain Relief in Hysterosalpingography
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Lidocaine Gel|DRUG: KY jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia
Status: RECRUITING
Conditions: Lewy Body Dementia|Parkinson Disease Dementia|Dementia With Lewy Bodies|Lewy Body Disease
Interventions: BEHAVIORAL: Peer Mentor Support and Caregiver Education|BEHAVIORAL: Caregiver Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: Docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating ACC-001 in Japanese Patients With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: ACC-001|OTHER: QS-21|BIOLOGICAL: ACC-001|OTHER: QS-21|OTHER: PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Automated System to Culture Metastatic Patient Circulating Tumor Cells in Embryonated Chicken Eggs (in Ovo Culture)
Status: RECRUITING
Conditions: Cancer Metastatic|Prostate Cancer|Breast Cancer|Lung Cancer|Ovarian Cancer|Gastric Cancer
Interventions: PROCEDURE: Patient sampling.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Difficult Airway
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: orotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Classified Treatment Strategy for De-novo Metastatic Breast Cancer After Systemic Adjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms|Treatment|Metastatic Breast Cancer|Survival
Interventions: PROCEDURE: surgical treatment 1|PROCEDURE: surgical treatment 2|DRUG: Systemic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of ST-0529 in Subjects With Moderately to Severely Active Ulcerative Colitis
Status: TERMINATED
Conditions: Colitis, Ulcerative
Interventions: DRUG: ST-0529
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brassica Vegetables or Indole-3-Carbinol in Treating Patients With PSA Recurrence After Surgery for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|DIETARY_SUPPLEMENT: Brassica vegetable|DRUG: indole-3-carbinol|OTHER: counseling intervention|OTHER: medical chart review|OTHER: questionnaire administration|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Lenalidomide Post Autologous Stem Cell Transplant (ASCT) in High-risk Multiple Myeloma (MM)
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Pembrolizumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1, 2, 4, 5 or 6 Infection and Compensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection|Chronic Hepatitis C|Compensated Cirrhosis
Interventions: DRUG: ABT-493/ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continence and Potency Following Multi-Layer Perinatal Issue alloGraft
Status: WITHDRAWN
Conditions: Post Operative Recovery
Interventions: DEVICE: MLG (Multi-Layered Perinatal Issue Allograft) Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zinc & Bone Health in Thalassemia: The Think Zinc Study
Status: COMPLETED
Conditions: Thalassemia
Interventions: DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety and Utility of PINPOINT® Near Infrared Fluorescence Imaging in the Identification of Lymph Nodes in Patients With Uterine and Cervical Malignancies Who Are Undergoing Lymph Node Mapping
Status: COMPLETED
Conditions: Endometrial Cancer|Uterine Cancer|Cervical Cancer
Interventions: DEVICE: PINPOINT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GOODBYE HARTMANN TRIAL: 100 YEARS OF HARTMANN'S PROCEDURE
Status: UNKNOWN
Conditions: Emergencies|Colon Disease|Colo-rectal Cancer|Volvulus Colon|Intussusception|Diverticulitis|Foreign Bodies
Interventions: PROCEDURE: Hartmann's procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Music Therapy for Pain Management in the NICU Setting
Status: COMPLETED
Conditions: Music Therapy
Interventions: BEHAVIORAL: music therapy selected by mothers|BEHAVIORAL: Music therapy recorded lullaby
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PHASE III RANDOMISED TRIAL TO EVALUATE FOLFOX WITH OR WITHOUT DOCETAXEL (TFOX) AS 1st LINE CHEMOTHERAPY FOR LOCALLY ADVANCED OR METASTATIC OESOPHAGO-GASTRIC CARCINOMA
Status: ACTIVE_NOT_RECRUITING
Conditions: OESOPHAGO-GASTRIC CARCINOMA
Interventions: DRUG: Oxaliplatin|DRUG: 5Fluorouracil bolus|DRUG: 5Fluorouracil continu|DRUG: Docetaxel|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC
Status: RECRUITING
Conditions: Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC)
Interventions: BIOLOGICAL: AZD2936
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma
Status: RECRUITING
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: IDE196|DRUG: Crizotinib|DRUG: Pembrolizumab|DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One-year Outcomes of Electromechanical Activation Time (EMAT)-Guided vs. Symptom-guided Heart Failure Therapy in Acute Heart Failure Syndrome (AHFS) Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Cardiophonogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between iLux™ and LipiFlow® in the Treatment of Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: iLux 2020 System|DEVICE: LipiFlow Pulsation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of First-line Antibiotic Therapy for Early-stage Gastric MALT Lymphoma for Treatment Outcome
Status: COMPLETED
Conditions: Gastric MALT Lymphoma
Interventions: DRUG: Omeprazole, Amoxicillin, Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of the Effect of Omega-3-acid Ethyl Esters (TAK-085) on Vascular Endothelial Function in Patients With Hyperlipidemia by Flow Mediated Dilation
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: TAK-085
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pancreatic Cancer Screening of High-Risk Individuals in Arkansas
Status: WITHDRAWN
Conditions: Pancreatic Neoplasms|Peutz-Jegher's Syndrome|BRCA1 Gene Mutation|BRCA2 Gene Mutation|Ataxia Telangiectasia|Familial Atypical Mole-Malignant Melanoma Syndrome|Colorectal Neoplasms, Hereditary Nonpolyposis|Hereditary Pancreatitis
Interventions: OTHER: Pancreatic Cancer Screening Pathway 1|OTHER: Pancreatic Cancer Screening Pathway 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Therapeutic Effect of Repetitive Transcranial Magnetic Stimulaton on Tinnitus
Status: COMPLETED
Conditions: Patients With Subjective Tinnitus
Interventions: DEVICE: real repetitive Transcranial Magnetic Stimulation|DEVICE: sham repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Patients With Recurrent or Persistent Uterine Cancer
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Sarcoma|Uterine Carcinosarcoma
Interventions: DRUG: Ixabepilone|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety of Hep C Vaccine Candidates in HIV Seropositive Individuals
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: BIOLOGICAL: AdCh3NSmut1|BIOLOGICAL: MVA-NSmut
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Standard dose (once daily) PPI plus low-dose antidepressant|DRUG: Double dose PPI plus evening placebo|DRUG: Rabeprazole , placebo, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Remote Ischemic Conditioning on Prehypertension and Early-stage Hypertension
Status: UNKNOWN
Conditions: Prehypertension|Remote Ischemic Conditioning|Early Stage Hypertension
Interventions: DEVICE: remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patellar Stability After MPFL Reconstruction With Fascia Lata Allograft: Conventional CT vs Under Weight-bearing CT
Status: COMPLETED
Conditions: Patellofemoral Dislocation
Interventions: DIAGNOSTIC_TEST: CT scan of the knee under weight-bearing with the Cone Beam Computed Tomography (CBCT) scanner system.|DIAGNOSTIC_TEST: Conventional CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics of Single and Multiple Oral Doses of BI 1356 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356 BS|DRUG: BI 1356 BS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
Status: TERMINATED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Derazantinib|DRUG: Derazantinib-paclitaxel-ramucirumab combination|DRUG: Derazantinib-paclitaxel-ramucirumab combination|DRUG: Derazantinib|DRUG: Derazantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic Arthritis
Status: UNKNOWN
Conditions: Psoriatic Arthritis
Interventions: DRUG: Open label H.P. Acthar Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstructive Surgery For Head And Neck Cancer Patients
Status: COMPLETED
Conditions: Advanced Stage Head and Neck Cancer
Interventions: BEHAVIORAL: Quality of Life Questionaires & Interview: EORTC QLQ C-30, EORTC QLQ H&N-35, Health Behaviors, Subjective Significance Questionnaire, Qualitative Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Rituximab on MRI Evidence of Disease Activity in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Proxalutamide (GT0918) in Hospitalized COVID-19 Subjects
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: GT0918|DRUG: Standard of care|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Revascularization Endarterectomy Versus Stenting Trial
Status: COMPLETED
Conditions: Atherosclerosis|Stroke|Carotid Stenosis|Cerebral Infarction|Myocardial Infarction
Interventions: PROCEDURE: Carotid Endarterectomy (CEA)|DEVICE: Carotid Artery Stenting (CAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Safety of Baricitinib in Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: DRUG: Baricitinib|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Removal of Intrauterine Retained Products of Conception (RPOC) After Miscarriage Guided by Hysteroscopy Trial. A Randomized Controlled Trial.
Status: RECRUITING
Conditions: Retained Products of Conception
Interventions: PROCEDURE: Operative hysteroscopy|OTHER: Expectant management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Electroacupuncture for Treatment of Simple Female Stress Urinary Incontinence: Comparison With Pelvic Floor Muscle Training-a Multicenter Randomized Controlled Trial
Status: UNKNOWN
Conditions: Simple Stress Urinary Incontinence
Interventions: DEVICE: electroacupuncture group|BEHAVIORAL: pelvic floor muscle training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Recurrent Esophageal Carcinoma|Recurrent Gastric Carcinoma|Stage IV Esophageal Cancer AJCC v7|Stage IV Gastric Cancer AJCC v7|Unresectable Esophageal Carcinoma
Interventions: DRUG: Epacadostat|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Arterial Phase Computed Tomography Examination to Improve Detection of Tumors in the Liver and Pancreas
Status: UNKNOWN
Conditions: Contrast Media|Computed Tomography|Imaging|Pancreatic Cancer|Hepatic Cancer
Interventions: DIAGNOSTIC_TEST: Computed Tomography of the Abdomen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcome of 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism
Status: RECRUITING
Conditions: Primary Aldosteronism
Interventions: DIAGNOSTIC_TEST: 68Ga-Pentixafor PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Gastric Cancer|Stage IIIB Gastric Cancer|Stage IIIC Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: bortezomib|DRUG: irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Mixed meal test|DRUG: Vildagliptin|DRUG: Sitagliptin|DRUG: Placebo|DRUG: Metformin|OTHER: Diet and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Effect of a Treatment With Zinkgluconaat for Verrucae Vulgares
Status: COMPLETED
Conditions: Verrucae Vulgares
Interventions: DRUG: Administration of zinkgluconaat or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Improvement of Black Raspberry in Obese and Mild AZ Patients Infected With H. Pylori
Status: COMPLETED
Conditions: Alzheimer Disease|H Pylori Infection
Interventions: DIETARY_SUPPLEMENT: Black raspberry|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glitazones and Endothelial Function (GATE)
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: rosiglitazone/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy
Status: RECRUITING
Conditions: Depressive Disorder, Major|Anhedonia
Interventions: DRUG: Aticaprant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Antagonistic Muscle Magnetic Stimulation and Selective Periferal Neurotomy to Improve Results on Spasticity
Status: NOT_YET_RECRUITING
Conditions: STROKE
Interventions: PROCEDURE: - Postoperative Antagonistic Peripheral Magnetic Stimulation|DEVICE: Selective Peripheral Magnetic Stimulation|OTHER: Kinesics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Patellar Taping and Isometric Strength Training on Quadriceps Strength With Patellofemoral Pain Syndrome.
Status: COMPLETED
Conditions: Patello Femoral Syndrome
Interventions: BEHAVIORAL: patellar taping combined with isometric strength training|BEHAVIORAL: sham patellar taping combined with isometric strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: GrOup-based Physical Activity for oLder Adults Trial
Status: COMPLETED
Conditions: Motor Activity
Interventions: BEHAVIORAL: Similar-Age-Same-Gender (SASG)|BEHAVIORAL: Similar-Age-Mixed-Gender (SAMG)|BEHAVIORAL: Mixed-Age-Mixed-Gender (MASG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prevalenc Of Lumbosacral Radiculopathy Among Physiotherapists Of Pediatric Rehabilitation OF PEDIATRIC REHABILITATION
Status: COMPLETED
Conditions: Prevalence, Lumbosacral Radiculopathy
Interventions: DIAGNOSTIC_TEST: Cross section study; single group related measurement design.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial
Status: COMPLETED
Conditions: Male Infertility
Interventions: DEVICE: PICSI|OTHER: Second ejaculate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients
Status: RECRUITING
Conditions: β-thalassemia
Interventions: BIOLOGICAL: β-globin restored autologous hematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effect of Mechanical and Functional Alignment in Bilateral Total Knee Arthroplasty on Ankle Alignment
Status: RECRUITING
Conditions: Arthropathy of Knee
Interventions: OTHER: Mechanical alignment|OTHER: Functional alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Tolerability of P 321 Ophthalmic Solution in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: P-321 Ophthalmic Solution|DRUG: P-321 Ophthalmic Solution placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Safety and Efficacy of the PDS-1.0 in Patients With Neovascular Age Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: PDS 1.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Splanchnic Magnetic Neuromodulation Therapy (ThorS-MagNT) for Grade 3 Diabetic Gastroparesis: Pilot Study
Status: UNKNOWN
Conditions: Diabetic Gastroparesis
Interventions: DEVICE: Thoracic Splanchnic Magnetic Neuromodulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity
Status: TERMINATED
Conditions: Chronic Allograft Injury|Calcineurin Inhibitor Toxicity
Interventions: DRUG: Everolimus|DRUG: Tacrolimus|DRUG: Mycophenolic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anti-Xa Levels in Surgery Patients Receiving Fixed Dose Heparin
Status: COMPLETED
Conditions: Deep-Venous Thrombosis|Pulmonary Embolism|Venous Thromboembolism
Interventions: DRUG: Real time heparin dose adjustment|DRUG: Standard heparin dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma
Status: COMPLETED
Conditions: Classic Hodgkin Lymphoma|Lugano Classification Stage III Hodgkin Lymphoma AJCC v8|Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8
Interventions: DRUG: Bleomycin|DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|BIOLOGICAL: Rituximab|DRUG: Vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anorectal Application of Dx-gel for Treatment of Anal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Anal injection of Nasha Dx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HCC Surveillance: Comparison of Abbreviated Non-contrast MRI and Ultrasound Surveillance in Cirrhotic Patients With Suboptimal Ultrasound Visualisation
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|HCC
Interventions: DIAGNOSTIC_TEST: Abbreviated non-contrast MRI of the liver|DIAGNOSTIC_TEST: Ultrasound surveillance|DIAGNOSTIC_TEST: Multiphase contrast-enhanced liver MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Preoperative PPI in Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: COMBINATION_PRODUCT: sleeve + preoperative PPI|COMBINATION_PRODUCT: sleeve + preoperative Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Leukaemia|Chronic Disease|Leukemia|Myelodysplasia|Lymphoma
Interventions: DRUG: Busulfan|DRUG: Anti-Thymocyte Globulin|DRUG: Fludarabine|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Validation of a New Biomarker to Determine Predisposition to Infections in Patients With Acute Myocardial Infarction.
Status: UNKNOWN
Conditions: Infections in Acute Myocardial Infarction Patients
Interventions: OTHER: prospective biomedical research study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Incontinence-associated Dermatitis and Maintenance of Local Skin Microclimate
Status: RECRUITING
Conditions: Incontinence-associated Dermatitis
Interventions: DEVICE: Jefcare Sterile Medical Sheets|DEVICE: MoliCare Premium Bed Mats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Types of Progestin on Sleeping of Menopausal Women
Status: COMPLETED
Conditions: Menopausal and Postmenopausal Disorders
Interventions: DRUG: 1mg 17 beta-estradiol|DRUG: Dydrogesterone|DRUG: micronized progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gluten-free Diet in Type 1 Diabetics With Dyspepsia Symptoms
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Gastroparesis|Dyspepsia|Gluten Sensitivity
Interventions: OTHER: Gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent Targeted Interventions in Vaccination Pain Management of Infants
Status: COMPLETED
Conditions: Procedural Pain
Interventions: BEHAVIORAL: MIAS&Q|BEHAVIORAL: Be Sweet to Babies Videos and Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Echocardiography-guided Transthoracic Radio Frequency/Laser Ablation for Ventricular Septum of Hypertrophic Obstructive Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: Echocardiography-guided transthoracic radio frequency ablation for HOCM ventricular septum|PROCEDURE: Echocardiography-guided transthoracic laser ablation for HOCM ventricular septum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: pamidronate disodium|DRUG: thalidomide|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea
Status: TERMINATED
Conditions: Clostridium Difficile Infection|Antibiotic Associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Bio K+® 2 capsules orally (or via nasogastric tube)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: OTHER: Western therapy|DRUG: TCM Syndrome Differentiation and Treatment|OTHER: Western therapy plus TCM treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study of R-CHOP vs Bortezomib-R-CAP for Young Patients With Diffuse Large B-cell Lymphoma With Poor IPI.
Status: COMPLETED
Conditions: Diffuse, Large B-Cell, Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS
Status: RECRUITING
Conditions: Subepithelial Gastrointestinal Tumors
Interventions: PROCEDURE: EUS Elastography (EUS-E)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Retrolaminar Block for Pediatric Inguinal Hernia
Status: UNKNOWN
Conditions: Inguinal Hernia|Pediatric
Interventions: PROCEDURE: General anaesthesia|PROCEDURE: Ultrasound-guided RLB|PROCEDURE: Ultrasound-guided INB|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Topical Tranexamic Acid With Floseal® in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Topical tranexamic acid|DRUG: Floseal®|DRUG: rivaroxaban (10mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients With Non-segmental Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: DIAGNOSTIC_TEST: Interleukin-15 and Interleukin-22
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome.
Status: COMPLETED
Conditions: Unstable Angina|Non-ST-Elevation Myocardial Infarction
Interventions: DEVICE: iSTAT point of care analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacological Reduction of Functional, Ischemic Mitral REgurgitation
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Left Ventricular Dysfunction
Interventions: DRUG: LCZ696|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Methadone Single Dose Reduces Postoperative Morphine Consumption.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas
Status: COMPLETED
Conditions: Brainstem Glioma|Neoadjuvant Therapy
Interventions: BIOLOGICAL: DNX-2401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva (Erlotinib) Monotherapy in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of ARN-6039
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: ARN-6039|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Energy Intake, Exercise and Constitutional Leanness
Status: COMPLETED
Conditions: Anorexia Nervosa|Constitutional Leanness
Interventions: BEHAVIORAL: REST-Fixed|BEHAVIORAL: REST-AdLib|BEHAVIORAL: EX-AdLib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 (THS 2.2)
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: THS 2.2|OTHER: CC|OTHER: NNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Preemptive Analgesia in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Celecoxib and Pregabaline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Excitability and Connectivity in Sensory-motor Pathways in ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: functional MRI|DEVICE: structural MRI|DEVICE: EEG/MEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Investigate Safety And Pharmacokinetics Of A Single Dose Of PF-00868554 (Filibuvir) In Japanese Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Active|DRUG: Placebo|DRUG: Active|DRUG: Placebo|DRUG: Active|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE