pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: MRI in Normal Ileal Pouches, and a Feasibility Study of Dynamic MRI Enema and Defaecating MRI Pouchography
Status: COMPLETED
Conditions: Colitis, Ulcerative|Ileal Pouches
Interventions: OTHER: MRI with ileal pouch contrast and enema.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Influence of Lutein Supplements on Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Lutein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part V
Status: COMPLETED
Conditions: Hypothermia|Newborn
Interventions: PROCEDURE: Resuscitation with torso plastic bag|PROCEDURE: Resuscitation-no plastic bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Sensitivity Following Placement With Different Restorative Materials In Vital Posterior Teeth
Status: RECRUITING
Conditions: Sensitivity, Tooth
Interventions: DRUG: Tetric N Bond Universal®|DRUG: Self Etch Tetric N Bond Universal®|DRUG: GC Fuji IX, GC, Japan®|DRUG: Activa TM Bioactive Restorative ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cognitive-Behaviour Therapy (CBT) Self-Management Approach for Insomnia in Chronic Pain: A Randomized Control Trial
Status: COMPLETED
Conditions: Insomnia|Chronic Pain
Interventions: BEHAVIORAL: Self-help manual for insomnia|BEHAVIORAL: Sleep diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch)
Status: TERMINATED
Conditions: Pruritus|Prurigo Nodularis|Atopic Dermatitis|Psoriasis
Interventions: DRUG: 5 mg Serlopitant Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epoetin Dosing Regimens in Haemodialysis
Status: COMPLETED
Conditions: Hemodialyzed Patients|Epoetin Treatment
Interventions: DRUG: NeoRecormon SC once-weekly versus once-every-other-week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Anal Imiquimod Therapy in Anal HPV-lesions: AdAM-trial
Status: NOT_YET_RECRUITING
Conditions: Anogenital Human Papillomavirus Infection|Condyloma Anal
Interventions: DRUG: Imiquimod 5% cream|DRUG: Placebo cream|PROCEDURE: Fulguration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DAPSONE GEL7.5%Versus Trichloroacetic Acid 20% ON ACNE VULGARIS
Status: UNKNOWN
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PErsonalized TReatment for Endometrial Carcinoma
Status: RECRUITING
Conditions: Endometrial Adenocarcinoma
Interventions: OTHER: Comparison of adjuvant therapies|OTHER: Comparison of adjuvant therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cardiorespiratory Events in Subjects Undergoing an Upper and/or Lower Endoscopy Under Current Sedation Practices
Status: COMPLETED
Conditions: Sedation for Non-Emergent Upper and/or Lower Endoscopy
Interventions: DEVICE: Passive monitoring with pulse-oximetry, NIBP and ECG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain|Postoperative Pain
Interventions: DRUG: Bupivacaine liposome|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag for Chemotherapy-induced Thrombocytopenia
Status: RECRUITING
Conditions: Chemotherapy-induced Thrombocytopenia|Eltrombopag
Interventions: DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ankle Robotics Training After Stroke
Status: COMPLETED
Conditions: Seated Treadmill Training|Treadmill Locomotor-based Training|Treadmill Only
Interventions: BEHAVIORAL: Seated Robot Training (SRT)|BEHAVIORAL: Treadmill Locomotor-based Training (TMR)|BEHAVIORAL: Treadmill Only (TMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Vaccine Responsiveness in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: PCV13 vaccine and any of the FDA-approved COVID-19 vaccine products (BNT162b2, mRNA-1273, or Ad26.COV2.S) based on local availability.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ellume.Lab Flu A+B Test and iTreat Flu A+B Flu Test Performance Versus Viral Culture and Reverse Transcriptase Polymerase Chain Reaction.
Status: COMPLETED
Conditions: Influenza
Interventions: DIAGNOSTIC_TEST: iTreat Flu A+B Test|DIAGNOSTIC_TEST: ellume.lab Flu A+B Test|DIAGNOSTIC_TEST: Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)|DIAGNOSTIC_TEST: Viral culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Ivermectin From Revemact 6 mg Tablets (Man. by EVA Pharma for Horus for Pharmaceutical Industries, Egypt) and Stromectol 2*3 mg Tablets (Merck Sharp & Dohme B.V., Haarlem, The Netherlands)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Revemact|DRUG: Stromectol (first dose)|DRUG: Stromectol (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Oral Contraceptive Pill for Premenstrual Worsening of Depression
Status: COMPLETED
Conditions: Premenstrual Syndrome|Depression
Interventions: DRUG: Drospirenone and ethinyl estradiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants
Status: COMPLETED
Conditions: Adrenomyeloneuropathy
Interventions: DRUG: N-acetylcysteine|DRUG: lipoic acid|DRUG: vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemicraniectomy in Patients With Malign Middle Cerebral Artery Infarction
Status: COMPLETED
Conditions: Cerebral Herniation
Interventions: PROCEDURE: Hemicraniectomy|OTHER: Conservative medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Health Intervention on Fear of Hypoglycemia : a Pilot Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Fear of Hypoglycemia|Health Education|Impaired Awareness of Hypoglycemia|Self-Management
Interventions: BEHAVIORAL: Based on BCW Theory of Health Education|BEHAVIORAL: General diabetes health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Minimally Invasive Surgery for Axillary Osmidrosis: Combined Liposuction With Subcutaneous Pruning
Status: UNKNOWN
Conditions: Sweat Gland Diseases
Interventions: PROCEDURE: minimally invasive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remineralization Efficacy of Gum Arabic Varnish.
Status: UNKNOWN
Conditions: Caries,Dental|Remineralization|White Spot Lesion
Interventions: DRUG: Gum Arabic varnish|DRUG: Proflourid Varnish,VOCO|DRUG: MI Varnish,GC Japan Inc.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cranial Reconstruction Using Mesenchymal Stromal Cells and Resorbable Biomaterials
Status: UNKNOWN
Conditions: Surgically-Created Resection Cavity
Interventions: PROCEDURE: Repair of cranial defects by tissue engineering
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crocus Sativus Extract Impact in Metabolic Control of Patients With Diabetes Mellitus Type 1
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes type1
Interventions: DIETARY_SUPPLEMENT: dietary supplement with probiotics, prebiotics, magnesium and saffron extract|DIETARY_SUPPLEMENT: dietary supplement with probiotics, prebiotics, magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Nutritional Intervention for Adolescents
Status: COMPLETED
Conditions: Early Intervention, Educational|Health Promotion|Feeding Behavior|Adolescent Health
Interventions: BEHAVIORAL: ALIADA: Alimentación, Adolescencia y Ambiente
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Effectiveness Study of Acetaminophen Extended Release (3900 mg/Day) and Ibuprofen (1200 mg/Day) in the Treatment of Pain Associated With Ankle Sprains.
Status: COMPLETED
Conditions: Sprains and Strains|Pain
Interventions: DRUG: acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Early Total Enteral Feeding Versus Convention Enteral Feeding in Preterm Infants 27-32 Weeks of Gestation
Status: COMPLETED
Conditions: Very Preterm Maturity of Infant|Enteral Feeding Intolerance
Interventions: OTHER: Early Total Enteral Feeding|OTHER: Conventional Enteral Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Advanced, Metastatic, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Bronchoalveolar Cell Lung Cancer|Large Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: paclitaxel|DRUG: carboplatin|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study
Status: RECRUITING
Conditions: Epileptic Spasms, Failed Hormonal Therapy
Interventions: OTHER: Modified Atkins diet|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ocular Electroacupuncture on Abducens Nerve Palsy
Status: UNKNOWN
Conditions: Abducens Nerve Paralysis
Interventions: OTHER: ocular electroacupuncture|OTHER: ocular acupuncture|OTHER: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Effects on Pain During Hysteroscopy Hysteroscopy: A Randomized Control Trial
Status: COMPLETED
Conditions: Pain and Hysteroscopy
Interventions: DEVICE: Virtual reality headset (The Guided Meditation VR App through Oculus Go headset)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Hypocretin/Orexin Antagonist on Neurocognitive Performance
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Almorexant|DRUG: Almorexant|DRUG: Zolpidem 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway
Status: RECRUITING
Conditions: Major Depressive Disorder|Major Depressive Disorder, Recurrent
Interventions: DEVICE: sham stimulation|DEVICE: accelerated intermittent theta burst stimulation|DEVICE: high frequency stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meditation or Health & Wellness Education Via Internet for Adults 50-80 Years Old
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness Meditation|BEHAVIORAL: Health & Wellness Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene
Status: COMPLETED
Conditions: Wound Heal|Postoperative Pain|Biopsy Wound|Wound; Mouth|Quality of Life|Dental Plaque|Gingival Inflammation
Interventions: DEVICE: Hydrogen Carbamide/Peroxide Gel|DEVICE: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-center,Randomized,Double-blind,Placebo-controlled,Phase 3 Study Evaluating Favipiravir in Treatment of COVID19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Favipiravir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Kinesio Taping on Mutational Falsetto
Status: COMPLETED
Conditions: Mutational Falsetto|Dysphonia
Interventions: DEVICE: Kinesio Tex Gold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis
Status: COMPLETED
Conditions: Juvenile Dermatomyositis
Interventions: DRUG: 3 MPDN pulse + PDN|DRUG: 3 MPDN pulse + PDN + CSA|DRUG: 3 MPDN pulse + PDN + MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Nutrition Supplement on Health Related Quality of Life
Status: COMPLETED
Conditions: Sleep|Stress|Health, Subjective|Inflammation|Cognitive Symptom
Interventions: DIETARY_SUPPLEMENT: Supplement Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Pilates Exercises Verses Muscle Energy Techniques Along With Kinesio Taping in Non-Specific Low Back Pain
Status: UNKNOWN
Conditions: Pilates Exercises With Kinesio Taping|Muscle Energy Techniques Along With Kinesio Taping
Interventions: DIAGNOSTIC_TEST: Pilates Exercises|DIAGNOSTIC_TEST: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Juvenile Postlumbar Puncture Headache After Puncture With Needles With Quincke Tip or With Sprotte Tip
Status: UNKNOWN
Conditions: Headache
Interventions: DEVICE: lumbar puncture with Quincke-design needles|DEVICE: lumbar puncture with Sprotte-design needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: S1 vs.Pemetrexed Plus Carboplatin in Patients With EGFR Wild Type Stage IIIB or IV Nonsquamous NSCLC
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: S1 80-120 mg/d|DRUG: pemetrexed 500 mg/m2|DRUG: carboplatin AUC=5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Hormone-Resistant Breast Cancer|Non Small Cell Lung Cancer|Mesothelioma
Interventions: DRUG: AG-01 Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vedolizumab in the Prophylaxis of Intestinal Acute Graft Versus Host Disease (aGVHD) in Participants Undergoing Allogeneic Hematopoietic Stem Cell (Allo-HSCT) Transplantation
Status: COMPLETED
Conditions: Hematopoietic Stem Cells
Interventions: DRUG: Vedolizumab Placebo|DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Adults to Evaluate the Safety and Immunogenicity of Different Doses of JNJ-63871860
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: ExPEC4V (4 : 4 : 4 : 4)|BIOLOGICAL: ExPEC4V (4 : 4 : 4 : 8)|BIOLOGICAL: ExPEC4V (8 : 8 : 8 : 8)|BIOLOGICAL: ExPEC4V (8 : 8 : 8 : 16)|BIOLOGICAL: ExPEC4V (16 : 16 : 16 : 16)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nutritional Therapy Enriched With Omega-3 in Patients With Lung Resection
Status: RECRUITING
Conditions: Lung Cancer|Surgery
Interventions: DIETARY_SUPPLEMENT: Fish oil enteral supplementation|DIETARY_SUPPLEMENT: Fish oil oral supplementation|DIETARY_SUPPLEMENT: Enteral nutrition without fish oil|DIETARY_SUPPLEMENT: Oral nutritional supplement without fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: BIOLOGICAL: EpiCord|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Incidence of Orthostatic Intolerance and Hypotension in Primary Unicompartmental Knee Arthroplasty (UKA)
Status: UNKNOWN
Conditions: Orthostatic Hypotension|Orthostatic Intolerance|Postoperative Complications
Interventions: OTHER: Standardized mobilization procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Clinical Investigation of Colgate Dual Zinc Toothpaste as Compared to Colgate Cavity Protection Toothpaste in Controlling Established Plaque and Gingivitis
Status: NOT_YET_RECRUITING
Conditions: Plaque, Dental|Gingivitis
Interventions: DRUG: zinc containing toothpaste|DRUG: MFP Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856 50 mg|DRUG: SEP-363856 75 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renalof in the Dissolution of Renal Calculi in Patients With Recurrent Calcic Lithiasis
Status: COMPLETED
Conditions: Recurrent Calcic Urolithiasis
Interventions: DIETARY_SUPPLEMENT: Renalof|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imagery Interventions for Auditory Vocal Hallucinations
Status: COMPLETED
Conditions: Auditory Hallucination|Hearing Voices When No One is Talking|Psychosis
Interventions: BEHAVIORAL: Imagery intervention for voice hearing (meta-cognitive imagery rescripting)|BEHAVIORAL: Imagery intervention for voice hearing (Imagery rescripting)|BEHAVIORAL: Imagery intervention for voice hearing (promoting positive imagery de novo)|BEHAVIORAL: Imagery intervention for voice hearing (visuospatial working memory tasks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of HLD200 in Children and Adolescents With ADHD
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder
Interventions: DRUG: HLD200 (methylphenidate hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ferric Carboxymaltose (Ferinject®) in Anemic Patients Anticipating Pancreatoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Cancer|Anemia
Interventions: DRUG: Ferinject (Ferric Carboxymaltose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of no Drainage Tube on Blood Loss and Recovery After High Tibial Osteotomy
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Drainage Tube|DRUG: Tranexamic Acid|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Agent JNJ-56022473 in MDS and AML Patients FAILING HYPOMETHYLATING AGENT BASED THERAPY
Status: TERMINATED
Conditions: Myelodysplastic Syndrome (MDS)|Acute Myeloid Leukemia (AML)
Interventions: DRUG: JNJ-56022473|PROCEDURE: Bone marrow analyses and CBC with differential|OTHER: Flow cytometry analyses|OTHER: Central biobanking|PROCEDURE: Histopathology analysis|GENETIC: Cytogenetic analysis|PROCEDURE: Serum chemistry|PROCEDURE: Automated CBC|PROCEDURE: Pregnancy Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gluten Free Diet in Preventing Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplant
Status: TERMINATED
Conditions: Graft Versus Host Disease|Hematopoietic Cell Transplantation Recipient
Interventions: OTHER: Dietary Intervention|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Sarilumab in Adults With COVID-19
Status: COMPLETED
Conditions: SARS-CoV 2|SARS
Interventions: DRUG: Sarilumab 200 MG/1.14 ML Subcutaneous Solution [KEVZARA]|DRUG: Sarilumab 400 MG/2.28 ML Subcutaneous Solution [KEVZARA]|DRUG: Best available treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PERSEUS-PS Randomized Controlled Trial
Status: TERMINATED
Conditions: Cardiac Arrest|Cardiopulmonary Arrest With Successful Resuscitation
Interventions: OTHER: PERSEUS CPR|OTHER: Standard CPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate as Second-Line Therapy for Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Pancreatic Cancer|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Skin Filler Injection in the Face
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)|DRUG: Placebo Peel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Persistent Atrial Fibrillation|Paroxysmal Atrial Fibrillation
Interventions: BEHAVIORAL: Moderate-intensity continuous training (MICT)|BEHAVIORAL: High-intensity interval training (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Treatment Satisfaction in Patients With PAH Rapidly Switched From Epoprostenol to Remodulin
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: treprostinil sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the HERV-W Env ANtagonist GNbAC1 for Evaluation in an Open Label Long-term Safety Study in Patients With Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: GNbAC1 Monoclonal Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of the FlexStent Self-Expanding Stent System
Status: COMPLETED
Conditions: Efficacy of the Study Device
Interventions: DEVICE: FlexStent Femoropopliteal Self-Expanding Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Multifocal Contact Lenses Worn on a Daily Disposable Basis
Status: COMPLETED
Conditions: Presbyopia|Myopia
Interventions: DEVICE: Nelfilcon A multifocal contact lens, investigational|DEVICE: Nelfilcon A multifocal contact lens, commercial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Maximum-Dose Pharmacokinetic Study of 7.5% Ibuprofen Cream (SST-0225) in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen Cream (SST-0225)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Relationship Between Vitamin D-mediated Th17 and Treg Cells and Parkinson's Disease
Status: COMPLETED
Conditions: Neurology|Immunology
Interventions: DRUG: Vitamin D|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structured Remote Surgical Coaching to Improve Operative Performance in Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Education|Coaching|Surgical|Laparoscopic|Cholecystectomy
Interventions: BEHAVIORAL: Surgical Training using Structured Remote Surgical Coaching in addition to Conventional Surgical Training|BEHAVIORAL: Surgical Training using Conventional Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Muscle Strength Evaluations in Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Truncal flexion-extension muscle power|OTHER: Truncal extension muscle power|OTHER: Cervical flexion muscle power|OTHER: Cervical extension muscle power|OTHER: Cervical lateral flexion muscle powers|OTHER: Shoulder flexion muscle power|OTHER: Shoulder extension muscle power|OTHER: Shoulder internal rotation muscle power|OTHER: Shoulder external rotation muscle power|OTHER: Shoulder abduction muscle power|OTHER: Hip flexion muscle power|OTHER: Hip extension muscle power|OTHER: Hip abduction muscle power|OTHER: Hip internal rotation muscle power|OTHER: Hip external rotation muscle power|OTHER: Bath Ankylosing Spondylitis Functional Index (BASFI)|OTHER: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)|OTHER: The Health assessment questionnaire (HAQ)|OTHER: Bath Ankylosing Spondylitis Metrology Index (BASMI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Primary Prophylaxis With Neulasta (Pegfilgrastim) Versus Secondary Prophylaxis After Chemotherapy in Elderly Subjects (>/= 65 Years Old) With Cancer
Status: COMPLETED
Conditions: Neutropenia|Breast Cancer|Lung Cancer|Non-Hodgkin's Lymphoma|Ovarian Cancer
Interventions: DRUG: Neulasta (pegfilgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reach Out and Read (ROR) in the Neonatal Intensive Care Unit (NICU) Study
Status: RECRUITING
Conditions: Anxiety|Parent-Child Relations|Literacy
Interventions: BEHAVIORAL: Reach Out and Read
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preterm Fetal Growth Restriction and Developmental Care
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: BEHAVIORAL: NIDCAP (Newborn Individualized Developmental Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of FMT Combined With Nivolumab in Gastric Cancer
Status: WITHDRAWN
Conditions: Gastric Adenocarcinoma|Esophagogastric Junction Adenocarcinoma|Esophagus Adenocarcinoma
Interventions: DRUG: XBI-302 + Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Acebilustat Sub-Protocol
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Acebilustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of BEY1107 in Combination With Temozolomide in Patients With Recurrent or Progressive Glioblastoma Multiforme (GBM)
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: BEY1107|COMBINATION_PRODUCT: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Continuous Verses Interval Aerobic Training in Spinal Cord Injury Patient
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Interval Aerobic Exercise training Group|OTHER: Continuous Aerobic Exercise training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Pre-diabetes|Obesity
Interventions: BEHAVIORAL: Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Nephrectomy/Nephron Sparing Surgery(NSS) Performed Via Lumbotomy
Status: UNKNOWN
Conditions: Erector Spinae Plane Block
Interventions: DRUG: Morphine PCA pump|PROCEDURE: ESP block|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotype
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: sorafenib, vorinostat and bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Palonosetron on Remifentanil for Preventing Emergence Cough in Female
Status: COMPLETED
Conditions: Gallbladder Diseases
Interventions: DRUG: Normal saline injection|DRUG: Palonosetron Injection [Aloxi]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Efficacy and Mechanism in Fecal Microbiota Transplantation in the Treatment of Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory (Acute or Chronic) Graft-Versus-Host Disease by the Infusion of Expanded in-Vitro Allogenic Mesenchymal Stem Cell
Status: UNKNOWN
Conditions: Graft-vs-Host Disease (GVHD)
Interventions: PROCEDURE: Mesenchymal stem cell (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Added to Intensive Chemotherapy in Older Patients With Acute Myeloid Leukemia (AML)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulligan Mobilization With and Without Dry Needling in Runner's Knee
Status: COMPLETED
Conditions: Runner's Knee
Interventions: OTHER: Mulligan mobilization with dry needling.|OTHER: Mulligan mobilization without dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM
Status: ACTIVE_NOT_RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Bone marrow derived mononuclear cells and G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Liver|Pancreatic Neuroendocrine Tumor|Stage I Pancreatic Neuroendocrine Tumor AJCC v8|Stage II Pancreatic Neuroendocrine Tumor AJCC v8|Stage III Pancreatic Neuroendocrine Tumor AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: On Label, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Finasteride in Patients Undergoing Transurethral Resection of the Prostate (TURP)
Status: WITHDRAWN
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Finasteride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention for Sustaining Health (NURISH) Trial
Status: NOT_YET_RECRUITING
Conditions: Cognitive Change|Metabolic Syndrome, Protection Against|Diet, Healthy
Interventions: OTHER: MIND Diet|OTHER: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Quadratus Lumborum Block Versus Fascia Iliaca Nerve Block for Patients Undergoing Total Hip Replacement
Status: UNKNOWN
Conditions: Hip Replacement
Interventions: PROCEDURE: TQL|PROCEDURE: FIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-375
Status: UNKNOWN
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: CKD-375|DRUG: D390
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum
Status: UNKNOWN
Conditions: Obesity|Wound Infection|Pregnancy
Interventions: DEVICE: Kerlix-AMD|OTHER: placebo--normal gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Study to Evaluate MEDI6383 Alone and in Combination With MEDI4736 in Adult Subjects With Select Advanced Solid Tumors
Status: COMPLETED
Conditions: Recurrent or Metastatic Solid Tumors
Interventions: BIOLOGICAL: MEDI6383|BIOLOGICAL: MEDI6383 and MEDI4736
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pelvic Tilt Exercises With and Without Facet Joint Manipulation in Patients With Maigne's Syndrome
Status: COMPLETED
Conditions: Back Pain
Interventions: OTHER: Group A|OTHER: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immediate Skin-To-Skin Contact and Early Breastfeeding During Caesarean Section
Status: COMPLETED
Conditions: Neonatal Hypoglycemia
Interventions: OTHER: Immediate SSC and early breastfeeding during CS|OTHER: Delayed SSC and breastfeeding after CS|OTHER: Routine newborn care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
Status: TERMINATED
Conditions: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)
Interventions: DEVICE: Implantation of intrabronchial valves (IBV) (Spiration IBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acute Dietary Supplementation With Grape Seed Extract on Aortic Stiffness, Arterial Pressure, and Blood Vessel Dilation in Collegiate Obese Individuals at Rest
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Grape seed extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of ProAlgaZyme on HDL Cholesterol in Individuals With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome|Hyperlipidemia
Interventions: DRUG: ProAlgaZyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of the Incidence of Colonization of Peripheral Venous Catheters After Skin Disinfection With 0.5% Sodium Hypochlorite, Preceded or Not by an Application of 70% Ethanol
Status: COMPLETED
Conditions: Skin Disinfection Before Peripheral Venous Catheter Insertion
Interventions: DRUG: 0.5% sodium hypochlorite solution|DRUG: 0.5% sodium hypochlorite solution and 70% ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-time Sonography in Detecting Inadvertent Esophageal Intubation Among Difficult Intubation Patients
Status: UNKNOWN
Conditions: Intubation; Difficult or Failed|Intubation Complication|Ultrasonography|Diagnostic Imaging
Interventions: PROCEDURE: Ultrasonography|PROCEDURE: Direct visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Synthetic Nitrile Male Condom Compared to Standard Latex Male Condom
Status: RECRUITING
Conditions: Sexually Transmitted Diseases
Interventions: DEVICE: Synthetic Nitrile Condom (61mm)|DEVICE: Control Latex Condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10 on Healthy People Aged 18-65(III-healthy)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Bacillus Calmette - Guerin|BIOLOGICAL: placebo of Bacillus Calmette - Guerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Needle Procedures Success Rate After Application of Ralydan vs EMLA in Children
Status: COMPLETED
Conditions: Procedural Pain Relief
Interventions: DRUG: Lidocaine/Tetracaine patch|DRUG: Lidocaine/Prilocaine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sodium Chloride and Contrast Nephropathy
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Kidney Failure, Acute|Heart Failure|Diabetes
Interventions: DRUG: Oral sodium chloride|DRUG: Intravenous sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tralokinumab Monotherapy for Children With Moderate-to-severe Atopic Dermatitis - TRAPEDS 1 (TRAlokinumab PEDiatric Trial no. 1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Tralokinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Index Changes With Ephedrine, Phenylephrine, Ondansetron and Norepinephrine During Spinal Anesthesia
Status: COMPLETED
Conditions: Cardiac Output, Low
Interventions: DRUG: cardiac output changes with "ephedrine"|DRUG: cardiac output changes with "phenylephrine"|DRUG: cardiac output changes with "ondansetron"|DRUG: cardiac output changes with "nor-epinephrine"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Combined NRT With Single NRT in Primary Care Clinics in Hong Kong
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine patch|DRUG: Nicotine gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linsitinib in Treating Patients With Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Carney Complex|Chondrosarcoma|Gastrointestinal Stromal Tumor|Paraganglioma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Linsitinib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B-dependant Rare AutoImmune diseaSES - Cohort of Patients With Suspected Diagnosis of Primitive Sjögren Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome
Interventions: OTHER: Blood, fluid, sells and urine samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aromatase Inhibitors for Treatment of Uterine Leiomyomas
Status: WITHDRAWN
Conditions: Symptomatic or Large Uterine Fibroids
Interventions: DRUG: Letrozole (aromatase inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caelyx, Cyclophosphamide and Herceptin in Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Liposomal Doxorubicin|DRUG: Cyclophosphamide|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Freethiadine tablets(part I)|DRUG: Freethiadine tablets (part II)|DRUG: Freethiadine placebo tablets|DRUG: entecavir tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER