pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Determine if Caffeine Accelerates Emergence From Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Caffeine|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Supraclavicular And Infraclavicular Approach For Right Subclavian Venous Catheterization
Status: COMPLETED
Conditions: Central Line Complication
Interventions: DEVICE: Comparison between Supraclavicular And Infraclavicular Approach For Ultrasound-Guided Right Subclavian Venous Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Revascularization StrategIes for ST Elevation Myocardial Infarction Trial
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction|Coronary Stenting|Primary Angioplasty
Interventions: PROCEDURE: Same sitting PCI with complete revascularization|PROCEDURE: Staged PCI with complete revsacularization >48 hours pf primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: OTHER: Preservative-free saline solution eyedrops|OTHER: Systane® ULTRA lubricant eyedrops|OTHER: OPTIVE® lubricating eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RE-GENERATION: The Safety and Performance of the Relay Pro and Relay NBS Pro Stent-graft Devices in the European Union (EU)
Status: COMPLETED
Conditions: Aorta, Thoracic Pathologies|Aortic Aneurysm, Thoracic|Aortic Aneurysm
Interventions: DEVICE: Thoracic Endovascular Aortic Repair (TEVAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citrus Extract, Sleep and Mental Wellbeing
Status: RECRUITING
Conditions: Sleep Disturbance
Interventions: DIETARY_SUPPLEMENT: Citrus extract|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Assessment of Failure Rate of Fixed Lingual Retainer Between Two Types of Light Cured Resin Composite
Status: RECRUITING
Conditions: Orthodontic Retainer
Interventions: OTHER: Transbond LR|OTHER: Transbond XT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP)
Status: UNKNOWN
Conditions: Emergencies|Cardiovascular Diseases|Neurovascular Disorders
Interventions: OTHER: Ultrasound scan of the internal jugular veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Omega-3 Supplementation in Cervix Cancer Patients Undergoing Chemoradiotherapy
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Cabotegravir 200 mg/mL|DRUG: Cabotegravir 400 mg/mL|DRUG: Recombinant human hyaluronidase PH20 (rHuPH20)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LCI-GER-NOS-TAB-001: Tablet for Geriatric Assessment
Status: COMPLETED
Conditions: Self Geriatric Assessment Measure (SGAM)
Interventions: OTHER: Self Geriatric Assessment Measure (SGAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia in Remission|Adult Acute Lymphoblastic Leukemia in Remission|Chronic Myelogenous Leukemia (CML)|Non-Hodgkin's Lymphoma (NHL) or Hodgkin's Disease (HD) in 2nd or Greater Complete Remission, Partial Remission|Chronic Lymphocytic Leukemia (CLL)|Multiple Myeloma (MM)|Myelodysplastic Syndrome (MDS)|Myeloproliferative Disorders
Interventions: DRUG: POL6326|PROCEDURE: Leukapheresis|PROCEDURE: PBSC Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2016_37
Status: COMPLETED
Conditions: Hearing Loss, Bilateral Sensorineural, Progressive
Interventions: DEVICE: Hearing Aid (Successor of Phonak Virto V)|DEVICE: Hearing Aid (Phonak Virto V)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Growth and Hypoallergenicity Study of a New Formula for Infants With Cow Milk Allergy
Status: COMPLETED
Conditions: Cow Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Neocate Infant|DIETARY_SUPPLEMENT: new Neocate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Evaluating Effects of Cosmos Caudatus (Ulam Raja) in T2DM Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DIETARY_SUPPLEMENT: Cosmos Caudatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Image-Guided Cochlear Implant Programming
Status: RECRUITING
Conditions: Cochlear Implant
Interventions: OTHER: Signal processing intervention of a biomedical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation Outcome on Recurrent Upper Respiratory Tract Infections in 6-15 Years Old Egyptian School Children
Status: COMPLETED
Conditions: Recurrent Upper Respiratory Tract Infections|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: iron fumerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Preemptive Intramuscular Diclofenac on Minimal Effective-Dose Bupivacaine Saddle Block for Minor Perianal Surgeries
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Declofenac|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Castration-Resistant Prostate Cancer|Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Nomogram to Predict Major Postoperative Complications After Cytoreductive Surgery and HIPEC Based on Pre and Peroperative Criteria: Which Patient Require Intensive Monitoring?
Status: COMPLETED
Conditions: Peritoneal Carcinomatosis
Interventions: PROCEDURE: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Laparoscopic Inguinal Hernia Repair|PROCEDURE: Open Inguinal Hernia Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of HepQuant SHUNT to Assess Liver Disease; Substudy Within GS-US-416-2124
Status: WITHDRAWN
Conditions: Severe Alcoholic Hepatitis
Interventions: DRUG: GS-4997|DRUG: Prednisolone|DEVICE: HepQuant SHUNT Test|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Versus High Pressure Suction Drainage After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: low pressure suction drainage|DEVICE: High pressure suction drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Wireless Capsule Endoscopy and CT Enterography in Obscure Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Gastrointestinal Bleeding
Interventions: PROCEDURE: CT enterography|DEVICE: video capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Use of Patient-Reported Outcome Measures for Improving the Inter-Rater Reliability of Common Terminology Criteria for Adverse Event Ratings
Status: RECRUITING
Conditions: Cancer
Interventions: OTHER: Patient-reported outcomes assessment|OTHER: CTCAE rating|OTHER: PRO data is displayed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study To Estimate The Relative Bioavailability of Ertugliflozin (PF-04971729, MK-8835) in Healthy Adult Participants (MK-8835-039)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ertugliflozin 10 mg tablet|DRUG: Ertugliflozin OC Fast|DRUG: Ertugliflozin OC Slow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Cognitive Effects and Potential Mechanisms of TBS in Subjects With MCI
Status: ENROLLING_BY_INVITATION
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: TBS for Amyloid-positive MCI|DEVICE: TBS for Amyloid-negative MCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cevostamab|DRUG: Tocilizumab|DRUG: Pomalidomide|DRUG: Daratumumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Probiotic and HMB Supplementation on Immune and Digestive Function in Special Operations Soldiers
Status: COMPLETED
Conditions: Military Training
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: HMB|DIETARY_SUPPLEMENT: BC30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 3, Multicenter, Open-label, Long-term Study of SYR-472 (25 mg) in Patients With Type 2 Diabetes Mellitus Complicated by Severe Renal Impairment or End-stage Renal Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Trelagliptin 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chest Imaging of Lung Nodule(s) Under High-frequency Non-invasive Ventilation (HF-NIV)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DIAGNOSTIC_TEST: HF-NIV-MR|DIAGNOSTIC_TEST: HF-NIV-PET|DIAGNOSTIC_TEST: MR|DIAGNOSTIC_TEST: PET/CT breath hold|DIAGNOSTIC_TEST: CPAP-MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care
Status: COMPLETED
Conditions: Dental Caries|Gingivitis
Interventions: BEHAVIORAL: Basic oral health education and motivation|BEHAVIORAL: Intensive oral health education and motivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Paxman Limb Cryocompression System (PLCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications
Status: COMPLETED
Conditions: Sudden Cardiac Death
Interventions: DEVICE: Ovatio VR 6250 or DR6550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: INtervention Study In overweiGHT Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Obesity|Weight Loss|Life Style|Overweight
Interventions: BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Binimetinib and Hydroxychloroquine in Patients With Advanced KRAS Mutant Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer|KRAS Mutation-Related Tumors
Interventions: DRUG: Binimetinib Pill|DRUG: Hydroxychloroquine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Pharmacokinetics of Meropenem in Severe Septic Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Meropenem Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of a Parenting Discussion Group in Panama, Central America
Status: COMPLETED
Conditions: Child Behavioural and Emotional Difficulties|Parenting Practices
Interventions: BEHAVIORAL: Triple P Positive Parenting Program Discussion Group "Dealing with Disobedience"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery
Status: COMPLETED
Conditions: Scheduled Laparoscopic Surgery
Interventions: DEVICE: Pupillometry guided analgesia (PP)|DRUG: Tailored remifentanil controlled infusion|DRUG: Tailored antihypertensive drug administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Vinflunine Versus Alkylating Agent in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastases
Interventions: DRUG: vinflunine|DRUG: Alkylating agent of physician choice registered in cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygenation in Treatment of Alcohol Dependence Syndrome
Status: COMPLETED
Conditions: Alcohol Withdrawal Symptoms|Delirium Tremens (DTs)
Interventions: DEVICE: Hyperbaric Oxygenation Therapy|DEVICE: Normobaric Oxygenation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Human Chorionic Gonadotropin (hCG) Test: A Novel Method to Evaluate the Ovarian Reserve
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: s.c. human chorionic gonadotropin (Pregnyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their Infants
Status: COMPLETED
Conditions: Clostridium Difficile Immunisation|Diphtheria|Diphtheria Immunisation|Pertussis|Tetanus|Tetanus Immunisation
Interventions: BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed|BIOLOGICAL: Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed onto aluminum hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Two Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation of FAMCOPE-ICU (Family Coping and Emotion Regulation Tool in the ICU)
Status: COMPLETED
Conditions: Emotion Regulation|Coping Skills
Interventions: BEHAVIORAL: FAMCOPE-ICU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Management of Soil-transmitted Helminthiasis and Strongyloidiasis
Status: UNKNOWN
Conditions: Helminthiasis|Strongyloides Stercoralis Infection
Interventions: DRUG: Ivermectin + Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Nephrotic Syndrome
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children
Interventions: DRUG: Rituximab|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Tirofiban With Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction
Status: RECRUITING
Conditions: Branch Atheromatous Disease
Interventions: DRUG: Tirofiban hydrochloride sodium chloride injection|DRUG: Tirofiban hydrochloride sodium chloride injection placebo|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: mRNA-1011.1|BIOLOGICAL: mRNA-1011.2|BIOLOGICAL: mRNA-1012.1|BIOLOGICAL: mRNA-1010|BIOLOGICAL: mRNA-1010.2|BIOLOGICAL: mRNA-1010.3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Etoposide|DRUG: Carboplatin or Cisplatin|RADIATION: Thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Decision Support for Deprescribing in Patients on Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease|Hypertension|Diabete Type 2|Renal Failure Chronic|Anemia|Medication Interaction
Interventions: OTHER: Medication reconciliation supplemented with MedSafer and deprescribing brochures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Eltrombopag To Initiate And Maintain Interferon Antiviral Treatment To Benefit Subjects With Hepatitis C Liver Disease
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: eltrombopag|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Imaging Study Using PET/CT to Characterize the Effect of Intravenous Reslizumab on Airway Inflammation
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Reslizumab|DRUG: Fludeoxyglucose F 18 (FDG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of H. Pylori Eradication on the Fate of H. Pylori-associated Gastric Polyp
Status: COMPLETED
Conditions: Gastric Polyp|Helicobacter Pylori Infection
Interventions: DRUG: H. pylori eradication (Amoxaxillin, Lanston, Clarithromycin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Efficacy of Everolimus and Neoral® in Adult Cardiac Transplant Patients With Established Allograft Vasculopathy
Status: COMPLETED
Conditions: Graft Rejection
Interventions: DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Pharmacokinetics of Orodispersible BT-11 in Active Eosinophilic Esophagitis
Status: WITHDRAWN
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: BT-11 low|DRUG: BT-11 high|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Steroids and Microcirculation In Cardiac Surgery
Status: TERMINATED
Conditions: C.Surgical Procedure|Cardiac
Interventions: DRUG: Solu-medrol or placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Sleep Apnea After General Anaesthesia With a MAD
Status: COMPLETED
Conditions: Peri-operative Medicine|Sleep Apnea
Interventions: DEVICE: Mandibular advancement device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Sensifree's Alpha Sensor Signal Morphology Compared to Arterial Line and PPG Signal Morphologies
Status: COMPLETED
Conditions: Blood Pressure Measurement
Interventions: DEVICE: Sensifree's Alpha sensor|DEVICE: Arrow® arterial catheterization kit (Teleflex)|DEVICE: GE Datex-Ohmeda Oxy-F Finger Clip Pulse Oximeter Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis
Status: COMPLETED
Conditions: Cannabis|Ketamine
Interventions: DRUG: Active Delta-9-THC|DRUG: Placebo Delta-9-THC|DRUG: Active Ketamine|DRUG: Placebo Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-label, Single-arm Extension Study to Evaluate the Long-term Safety of Denosumab Administration in Postmenopausal Women With Low Bone Mineral Density
Status: COMPLETED
Conditions: Low Bone Mineral Density
Interventions: DRUG: AMG 162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Initial Routine PICC and General IV Access in Terminally Ill Cancer Patients
Status: COMPLETED
Conditions: Peripherally Inserted Central Catheter|Intravenous Access
Interventions: DEVICE: peripherally inserted central catheter (PICC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Formulations (Both Refrigerated and Room Temperature) Using an Autoinjector Device in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Sodium chloride|DRUG: Citrate buffer|DRUG: Mannitol|DEVICE: Prefilled Autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of Calm for Cancer Prototype Mobile App
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Calm Meditation Smartphone App Feedback|OTHER: Cancer-Specific Meditation App Prototype Design|DEVICE: Cancer-Specific Meditation App Prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Late Phase Acute Pancreatitis: a Tailored Step-up Approach
Status: COMPLETED
Conditions: Acute Pancreatitis
Interventions: PROCEDURE: percutaneous drainage|PROCEDURE: endoscopic approach|PROCEDURE: surgical internal derivation of WON|PROCEDURE: surgical necrosectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Ph 2 Study of Fosbretabulin in Subjects w Pancreatic or Gastrointestinal Neuroendocrine Tumors w Elevated Biomarkers
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: fosbretabulin tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Endoscopic RFA in Prolonging the Patency of Metal Stents in Patients With Malignant Obstructive Jaundice
Status: UNKNOWN
Conditions: Jaundice Extrahepatic Obstructive|Disorder of Bile Duct Stent
Interventions: PROCEDURE: Endoscopic radio-frequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of US-Guided Paravertebral and Proximal Intercostal Nerve Blocks
Status: UNKNOWN
Conditions: Pain
Interventions: PROCEDURE: Proximal Intercostal Block|PROCEDURE: Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomised Study of Concomitant Radiochemotherapy in Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Carcinoma
Interventions: DRUG: Concomitant Radiochemotherapy - Radiotherapy 66 Gy, Cisplatin, and Docetaxel|DRUG: Concomitant Chemoradiotherapy - Radiotherapy 66 Gy, Cisplatin, and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Imiquimod Cream 5%
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod 5% manufactured by Taro|DRUG: Aldara - Imiquimod 5%|DRUG: Imiquimod Vehicle manufactured by Taro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimensional Changes: Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Gum Graft Placed on Denuded Bone|PROCEDURE: Gum Graft Placed on Split Thickness Periosteal Bed Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study Of Palbociclib (PD-0332991) In Combination With Letrozole As Treatment Of Post-Menopausal Women With HR-Positive, Her2-Negative Advanced Breast Cancer For Whom Letrozole Therapy Is Deemed Appropriate
Status: NO_LONGER_AVAILABLE
Conditions: Advanced Breast Cancer (Female)
Interventions: DRUG: Palbociclib|DRUG: Letrozole
Study Type: EXPANDED_ACCESS
Clinical trial: A Multimodal Approach to Cervical Dystonia Treatment With Association of Botulinum Toxin and Motor Learning Techniques
Status: UNKNOWN
Conditions: Cervical Dystonia,Primary
Interventions: COMBINATION_PRODUCT: Botulinum Toxin+SPRInt
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine, 300 units per milliliter (U/mL)|DRUG: Background therapy: Rapid Acting meal time insulin analogs (Humalog, Novolog or Apidra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Plus Relatlimab or Ipilimumab in Metastatic Melanoma Stratified by MHC-II Expression
Status: TERMINATED
Conditions: Metastatic Melanoma|Advanced Melanoma|Metastatic Melanoma Stratified by MHC-II Expression
Interventions: DRUG: Nivolumab|DRUG: Relatlimab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJM347 in Healthy Male Caucasian and Japanese Subjects in the Fasted and Fed State
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AJM347|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: LY3819253|BIOLOGICAL: Placebo|BIOLOGICAL: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Irinotecan & Capecitabine in Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms|Secondary|Drug Therapy, Combination
Interventions: DRUG: Irinotecan, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Combination Chemotherapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IV Peripheral T-Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma|Small Intestine Cancer
Interventions: BIOLOGICAL: alemtuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisolone|DRUG: vincristine sulfate|GENETIC: polymerase chain reaction|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Neuroprotection of Sevoflurane Preconditioning on Intracranial Aneurysm Surgery
Status: UNKNOWN
Conditions: Brain Ischemia
Interventions: PROCEDURE: Sev-I group|PROCEDURE: Sevo continuous inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of HRS-5965 Tablets in Primary IgA Nephropathy
Status: NOT_YET_RECRUITING
Conditions: Primary IgA Nephropathy
Interventions: DRUG: HRS-5965|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FEC With G-CSF Support Followed by Ixabepilone With G-CSF Support as Neoadjuvant Chemotherapy in BC
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Efficacy And Safety Of Actikerall® Solution In Patients With Grade I-II Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 5-fluorouracil/salicylic acid|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Abatacept in Patients With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Methotrexate|OTHER: Abatacept Placebo|OTHER: Methotrexate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial Impact of Orange Juice Consumption on Risk Factors Associated With Cardiovascular Diseases
Status: COMPLETED
Conditions: Cardiovascular Risk Factors
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: 100% Florida OJ|DIETARY_SUPPLEMENT: 100% Florida OJ-enriched
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Primary vs Secondary Closure of Tracheo-cutaneous Fistulas
Status: RECRUITING
Conditions: Tracheostomy Complication|Post Tracheostomy Complications|Tracheostomy
Interventions: PROCEDURE: Primary closure of tracheo-cutaneous fistula|PROCEDURE: Secondary closure of tracheo-cutaneous fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Proximal Motor Control in Treating Lateral Epicondylitis
Status: UNKNOWN
Conditions: Lateral Epicondylitis
Interventions: OTHER: Strength of lower trapezius|OTHER: Strength of middle trapezius|OTHER: Strength of serratus anterior|OTHER: Pulsed ultrasound|OTHER: Stretching of extensor carpi radialis brevis muscle|OTHER: Eccentric exercises of wrist extensors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Construction and Preliminary Application of COM-B Based Sedentary Behavioural Booster Intervention Programme for Elderly Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: Sedentary behaviour intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Dronedarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib for Advanced Thymus Cancer Following Earlier Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Thymoma|Thymus Neoplasms
Interventions: DRUG: Sunitinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention of Bladder Cancer by CAR-T
Status: UNKNOWN
Conditions: Bladder Cancer|Urothelial Carcinoma Bladder
Interventions: GENETIC: 4SCAR-PSMA|GENETIC: 4SCAR-FRa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy
Status: RECRUITING
Conditions: Myomectomy; Surgical Blood Loss
Interventions: DRUG: Misoprostol 100Mcg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Immunogenicity Following a Heterologous Booster Dose of Recombinant SARS-CoV-2 Vaccine LYB002
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: LYB002V14|BIOLOGICAL: LYB002V14A|BIOLOGICAL: LYB002CA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Refractory Solid Tumors|Advanced Cancer
Interventions: DRUG: ASP4132
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: End-Stage Renal Disease Intra-dialysis Lifestyle Education Study
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: BEHAVIORAL: Intradialysis-yoga|BEHAVIORAL: Educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chatbot Effectiveness for Improving Mental Health and Reducing Stress in Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Mental Health|Stress|Nursing Education
Interventions: BEHAVIORAL: Line Bot Assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interval Training and Resting Metabolism
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: BEHAVIORAL: 1 x 4 minute interval|BEHAVIORAL: 4 x 4 minutes Intervals|BEHAVIORAL: Moderate continuous Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of Ocrelizumab on Immune Responses In Participants With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: 23-PPV|BIOLOGICAL: 13-PCV Booster|BIOLOGICAL: Influenza Vaccine|BIOLOGICAL: KLH|DRUG: OCR|BIOLOGICAL: TT Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact on Mortality of a Strategy Including Continuous Positive Airway Pressure Plus High Flow Nasal Cannula Oxygen Therapy Versus High Flow Nasal Cannula Oxygen Therapy Alone in Patients With de Novo Acute Hypoxemic Respiratory Failure: a Prospective, Randomized Controlled Trial.
Status: NOT_YET_RECRUITING
Conditions: De Novo Hypoxemic Acute Respiratory Failure (hARF)
Interventions: OTHER: HFNC|OTHER: CPAP and HFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Varenicline in Ambivalent Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Tobacco Use Cessation|Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Alone vs. Chemotherapy + Surgical Resection in Patients With Limited-metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Trastuzumab|DRUG: sodium folinate|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Responses to Gluten
Status: RECRUITING
Conditions: Celiac Disease|Malabsorption Syndromes|Digestive System Disease|Intestinal Disease|Gastrointestinal Diseases|Gluten Sensitivity|Celiac Disease in Children
Interventions: DIETARY_SUPPLEMENT: Gluten Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Intracranial Thrombus Aspiration Catheter in the Treatment of Acute Large-vessel Occlusive Stroke
Status: TERMINATED
Conditions: Aspiration|Acute Ischemic Stroke|Large-vessel Occlusion
Interventions: DEVICE: Intracranial Thrombosis Aspiration Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Combination With GA101 (Obinutuzumab) in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: GA101|DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Examination of the Safety and Blood Pressure Lowering Effect of Increasing Doses of Benicar® and Benicar® HCT in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Olmesartan medoxomil|DRUG: Olmesartan medoxomil/hydrochlorothiazide|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lysyl Oxidase, Semaphorin 7a and Semaphorin 3a in Patients With Systemic Sclerosis
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: OTHER: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome
Status: TERMINATED
Conditions: Sjögren Syndrome
Interventions: DRUG: Remibrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI8897 in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: MEDI8897 Intravenous|DRUG: Placebo|DRUG: MEDI8897 Intravenous|DRUG: MEDI8897 Intravenous|DRUG: MEDI8897 Intramuscular|DRUG: MEDI8897 Intramuscular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: idebenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma
Status: RECRUITING
Conditions: Chloasma
Interventions: DEVICE: Ultra-pulsed Shockwave Therapy Device by Shenzhen Lifotronic Technology Co., Ltd.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Open flap debridement|PROCEDURE: perforated membrane|PROCEDURE: leucocyte - platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Regulatory Requirement Post-Marketing Surveillance Study to Monitor the Safety and Efficacy of Twynsta (Telmisartan + Amlodipine SPC, q.d.) in Korean Hypertensive Patients Requiring Combination Therapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Twynsta tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RVU120 in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|High-risk Myelodysplastic Syndrome
Interventions: DRUG: RVU120(SEL120)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture Patients
Status: UNKNOWN
Conditions: Hip Fractures|Delirium
Interventions: PROCEDURE: Fascia-Iliaca Block(FIB)|PROCEDURE: Femoral Nerve Block(FNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia|Astigmatism|Hyperopia|Refractive Error
Interventions: DEVICE: FID 120947A contact lens disinfecting solution|DEVICE: renu fresh multi-purpose solution|DEVICE: Soft contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perampanel Single Ascending Dose Transcranial Magnetic Stimulation Biomarker Study in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Perampanel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER