pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intraprocedural Determination of Myocardial Vitality Using 2 Different Imaging Methods
Status: UNKNOWN
Conditions: Angina Pectoris|Left Ventricular Wall Motion Abnormalities
Interventions: DEVICE: Cardiac ultrasound|DEVICE: MRI scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Home Monitoring to Decrease the Treatment Burden for Neovascular Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Neovascular Age Related Macular Degeneration
Interventions: DRUG: Lucentis (Treat and extend)|DRUG: Lucentis every 4 weeks|DRUG: Lucentis every 12 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and CHOP in Patients With Advanced Stage Aggressive T Cell or Natural Killer (NK)/T Cell Lymphomas
Status: COMPLETED
Conditions: Peripheral T-Cell Lymphomas|Non-Hodgkin Lymphoma
Interventions: DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fixed or Self-Titrated Dosages of Sativex on Cannabis Users
Status: COMPLETED
Conditions: Cannabis Dependence
Interventions: DRUG: Sativex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers
Status: COMPLETED
Conditions: Cholangiocarcinoma Cancer|Gallbladder Cancer|Pancreatic Cancer|Ampullary Cancer
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-World Study on Extranodal Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma|Lymphoma, B-Cell|Lymphoma, Non-Hodgkin|Extranodal Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: OTHER: No interventions need to be specified for this study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Locally Advanced Bladder Carcinoma|Locally Advanced Bladder Urothelial Carcinoma|Locally Advanced Lung Non-Small Cell Carcinoma|Locally Advanced Renal Pelvis Carcinoma|Locally Advanced Renal Pelvis Urothelial Carcinoma|Locally Advanced Ureter Urothelial Carcinoma|Locally Advanced Urethral Urothelial Carcinoma|Malignant Solid Neoplasm|Metastatic Bladder Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Melanoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Carcinoma|Metastatic Urethral Urothelial Carcinoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Stage III Bladder Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Bladder Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Lung Cancer AJCC v6|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Unresectable Melanoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvent Chemotherapy Followed by SBRT in Patients With Resectable and Borderline Resectable Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combination of Sorafenib With Cisplatin and 5-fluorouracil as First-line Treatment of Recurrence After Radiotherapy Patients Who Failed With Radiotherapy in Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Sorafenib plus Cisplatin and 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Auricular Point Acupressure in Improving Quality of Life in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Auricular Point Acupressure group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alleviating Carbohydrate Counting for Patients With Type-1 Diabetes Using a Closed Loop System With Weekly Subcutaneous Semaglutide
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes|Diabetes Mellitus
Interventions: DRUG: Semaglutide with 4 meal strategies|DRUG: Placebo with 4 meal strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heparin vs Placebo for Cardiac Catheterization
Status: RECRUITING
Conditions: Cardiac Disease
Interventions: DRUG: Heparin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs as a Means of Predicting Drug-drug Interactions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cenobamate|DRUG: midazolam|DRUG: Warfarin Pill|DRUG: Omeprazole Pill|DRUG: Bupropion Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome X
Interventions: DRUG: Intravenous infusion of Intralipid/heparin|DRUG: Intravenous infusion of Glycerol/heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: ECT
Clinical trial: The Effect of Cinnamon on Ovulation Induction in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Ovulation
Interventions: DRUG: Cinnamon Cap 500 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Responses in Patients With B Cell Malignancies
Status: RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: Fluzone|BIOLOGICAL: Shingrix|BIOLOGICAL: Flucelvax|BIOLOGICAL: Afluria|BIOLOGICAL: PREVNAR 13|BIOLOGICAL: Heplisav -B|BIOLOGICAL: Pfizer-COVID-19 Vaccine|BIOLOGICAL: FluLaval|BIOLOGICAL: Fluarix|BIOLOGICAL: PNEUMOVAX 23|DRUG: PREVNAR 20|DRUG: AREXVY, ABRYSVO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients
Status: UNKNOWN
Conditions: Malignant Neoplasm of Nasopharynx
Interventions: DIETARY_SUPPLEMENT: Nutrison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rapid Versus Conventional Titration of Quetiapine in Schizophrenia/Schizoaffective Disorder
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorders|Psychotic Disorders
Interventions: DRUG: Quetiapine IR (Immediate Release)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaysia Diabetes Ramadan Nutrition Plan (My Dia-RNP®): A Feasibility Study
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Nutrition Intervention based on My Dia-RNP|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degeneration
Status: TERMINATED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: bevacizumab intravitreal injection|PROCEDURE: verteporfin photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Resolution HBA-MRI Using Deep Learning Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Diseases|Magnetic Resonance Imaging|Deep Learning
Interventions: DIAGNOSTIC_TEST: Liver MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Change in the DA Ratio, IR and SSI as Parameters of Corneal Biomechanics Post Different LVC Procedures
Status: COMPLETED
Conditions: Corneal Biomechanics
Interventions: DIAGNOSTIC_TEST: CORVIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient
Status: UNKNOWN
Conditions: Hypersensitivity|Dentin Sensitivity
Interventions: DRUG: Bifluorid 10 ,VOCO|DRUG: Sodium Fluoride 5% Dental Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Troriluzole in Adult Subjects With Spinocerebellar Ataxia
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinocerebellar Ataxias|Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 6|Spinocerebellar Ataxia Type 7|Spinocerebellar Ataxia Type 8|Spinocerebellar Ataxia Type 10
Interventions: DRUG: troriluzole|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Lung Neoplasms
Interventions: DRUG: paclitaxel|DRUG: cisplatin|PROCEDURE: chest radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ultramicronized PEA (Normast) in Spinal Cord Injury Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain|Spinal Cord Injury
Interventions: DIETARY_SUPPLEMENT: Ultramicronized PEA (Normast)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab Treatment in Graves´ Ophthalmopathy (Graves´ Orbitopathy or Thyroid Eye Disease)
Status: COMPLETED
Conditions: Thyroid Associated Ophthalmopathies|Graves´ Ophthalmopathy|Thyroid Eye Disease
Interventions: DRUG: Tocilizumab (RoActemra®)|DRUG: Sterile 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
Status: RECRUITING
Conditions: HIV Infections|Substance Use|Adherence, Medication|Adherence, Treatment
Interventions: DRUG: Descovy or Truvada|DEVICE: ID-Cap System|DEVICE: Beiwe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: peficitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gas Usage for Those With COPD Who Experience Low Oxygen Levels During Activities Only
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer
Interventions: DRUG: Bafetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation
Status: COMPLETED
Conditions: Brain Edema|Metabolic Disturbance|Electrolyte and Fluid Balance Conditions
Interventions: DRUG: Mannitol|DRUG: NaCl 7.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of KPI-121 in Subjects With DED
Status: COMPLETED
Conditions: Kerato Conjunctivitis Sicca
Interventions: DRUG: KPI-121 Ophthalmic Suspension|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Magnetic Resonance Coronary Angiography (MRCA) With Coronary Computed Tomography Angiography (CTA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Magnetic Resonance Angiography
Interventions: DIAGNOSTIC_TEST: Non-contrast magnetic resonance coronary angiography (MRCA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Adult Patients With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Exploratory study on patient's perception of Asthma symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Palliative Short-course Hypofractionated Radiotherapy Followed by Chemotherapy in Adenocarcinoma of the Esophagus or Esophagogastric Junction Trial - a Phase II Clinical Trial Protocol.
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagus or Esophagogastric Junction
Interventions: RADIATION: Radiation therapy|DRUG: Oxaliplatin and fluorouracil.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Nexvax2 in Subjects With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: BIOLOGICAL: Nexvax2|BIOLOGICAL: Nexvax2 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low- Load- High- Repetitions Training Versus Pilates on Physical Fitness in Inactive Women
Status: COMPLETED
Conditions: Sedentary Behavior
Interventions: OTHER: Low- weight-high-repetitions training|OTHER: Pilates training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Universal Ultrasound-screening for Developmental Dysplasia of the Hip in Newborn
Status: UNKNOWN
Conditions: Developmental Dysplasia of the Hip (DDH)
Interventions: OTHER: open, prospective cohort-study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of 2 Doses of Live Attenuated Varicella Vaccine
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: varicella-1|BIOLOGICAL: varicella-3|BIOLOGICAL: varicella-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ferric Carboximaltose on Intra-myocardial Iron Load in Patients With Heart Failure
Status: UNKNOWN
Conditions: Cardiac Failure|Systolic Heart Failure|Heart Failure, Systolic
Interventions: DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity Study of Investigational Recombinant Botulinum Vaccine A/B (rBV A/B) in Volunteers Previously Immunized With Investigational Pentavalent Botulinum Toxoid
Status: COMPLETED
Conditions: Botulism
Interventions: BIOLOGICAL: rBV A/B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bilateral Sacroiliac Joint (SIJ) Injection in Lumbar Disc Prolapse
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Sciatica|Low Back Pain, Mechanical|Spine Stiffness
Interventions: PROCEDURE: Bilateral SIJ injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: AZA Combined With RCHOP in P53-mutated DLBCL.
Status: RECRUITING
Conditions: DLBCL - Diffuse Large B Cell Lymphoma|TP53
Interventions: DRUG: Azacitidine in combination with R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Intervention for Training Auditory Attention in Adolescents With Autism Spectrum Disorder
Status: WITHDRAWN
Conditions: Autism Spectrum Disorder|Autism
Interventions: BEHAVIORAL: video game training exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy
Status: SUSPENDED
Conditions: Lymphedema, Breast Cancer|Lymphedema
Interventions: PROCEDURE: axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA)|PROCEDURE: Axillary lymphadenetomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Habituation Exercises Versus Proprioceptive Training in Benign Paroxysmal Positional Vertigo
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: OTHER: Habituation exercises + vestibular treatment|OTHER: proprioceptive training + vestibular therapy|OTHER: conventional vestibular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: gene expression analysis|GENETIC: gene rearrangement analysis|GENETIC: polymerase chain reaction|GENETIC: protein analysis|GENETIC: western blotting|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women
Status: COMPLETED
Conditions: Anesthetic, Sedative or Analgesic Complications in Labor or Delivery
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Formulations of Clopidogrel Film-coated Tablets 75 mg in Healthy Male Subjects Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Clopidogrel film-coated tablet 75 mg|DRUG: Plavix® film-coated tablet 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension
Status: UNKNOWN
Conditions: Obesity|Hypertension
Interventions: DRUG: Moxonidine 0.4 MG|DRUG: Amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acellular Dermal Matrix in Tissue Expander Breast Reconstruction: A Prospective, Randomized, Clinical Trial Comparing SurgiMend PRS and AlloDerm RTU
Status: COMPLETED
Conditions: Breast Cancer|Mastectomy
Interventions: DEVICE: AlloDerm RTU|DEVICE: SurgiMend PRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1002670 (Vilaprisan)
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Vilaprisan (BAY1002670)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: Nivolumab|DRUG: Degarelix|DRUG: BMS-986253
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Utilization Study on Diane-35 (and Generics) in Three European Healthcare Databases
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Cyproterone / Ethinylestradiol (Diane-35, BAY86-5264) and its Generics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia
Status: COMPLETED
Conditions: Mixed Dyslipidemia|Hypercholesterolemia
Interventions: DRUG: Fluvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of Acetaminophen Extended Release Caplets in the Treatment of Osteoarthritis of the Hip or Knee.
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: acetaminophen extended release|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fenugreek Seed and Lespedeza Cuneata in TDS
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: TFG capsules (200 mg /capsule)|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Efficacy of Investigational Products on Spontaneous Bowel Movements in Healthy People With ≤ 3 Complete Weekly Spontaneous Bowel Movements
Status: COMPLETED
Conditions: Functional Constipation|Healthy
Interventions: DIETARY_SUPPLEMENT: Actazin (green kiwi powder) High Dose|DIETARY_SUPPLEMENT: Actazin (green kiwi powder) Low Dose|DIETARY_SUPPLEMENT: Control Formula (Actazin green kiwi powder + PreticX prebiotic)|DIETARY_SUPPLEMENT: Livaux (gold kiwi powder) High Dose|DIETARY_SUPPLEMENT: Livaux (gold kiwi powder) Low Dose|DIETARY_SUPPLEMENT: Placebo (microcrystalline cellulose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis|Hip Infection|Prosthetic Joint Infection|Complications; Arthroplasty, Infection or Inflammation|Complications; Arthroplasty
Interventions: PROCEDURE: Implantation of a static, non-articulating cement spacer.|PROCEDURE: Implantation of an articulating spacer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: COPD plus CAPTURE education and patient-level information|OTHER: COPD Education Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Low-Density Lipoprotein Cholesterol-targeting Statin Therapy Versus the Intensity-based Statin Therapy in Patients With Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Diseasse
Interventions: DRUG: fixed high potent statin therapy|DRUG: targeted LDL-C goal statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation
Status: COMPLETED
Conditions: Diarrhea|Constipation
Interventions: DIETARY_SUPPLEMENT: probiotics (antibiophilus(Lactobacillus casei), bio-three)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy of Chest Tube Drainage and Needle Aspiration in Pneumothorax Treatment
Status: UNKNOWN
Conditions: Pneumothorax Spontaneous Primary|Pneumothorax, Recurrent|Pneumothorax Spontaneous Tension|Pneumothorax, Spontaneous
Interventions: PROCEDURE: Chest tube drainage|PROCEDURE: Repetitive needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRD
Status: COMPLETED
Conditions: Treatment Resistant Major Depressive Disorder
Interventions: DRUG: Aripiprazole|DEVICE: Repetitive transcranial magnetic stimulation (rTMS)|DRUG: Venlafaxine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scapular Movement Training Versus General Exercises for Individuals With Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Musculoskeletal Disease|Joint Disease|Shoulder Injury
Interventions: OTHER: Scapular Movement Training|OTHER: General Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRediction of Outcome With ED Intervention for Colles Type Wrist Fractures [PREDICT]
Status: COMPLETED
Conditions: Colles' Fracture|Colles' Fracture of Unspecified Radius, Sequela
Interventions: DIAGNOSTIC_TEST: Analysis of primary radiograph and available demographics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesia Effects of Intravenous Ketamine After Spinal Anesthesia for Non-elective Cesarean Section
Status: COMPLETED
Conditions: Non Elective Cesarean Section and Ketamine Analgesia
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Structural Approach to Implement the Role of 'Physical Activity Counselors' in Sports and Exercise Promotion
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: OTHER: General Practitioners|OTHER: Social-cultural organizations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of New Topical Preparation for Treatment of Acne Vulgaris
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: DAP-FLU ME|DRUG: Adapalene .1% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Pemetrexed|DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation
Status: COMPLETED
Conditions: Preoperative Skin Preparation
Interventions: DRUG: OCT - clear|DRUG: OCT- tinted|OTHER: ChloraPrep|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of a Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department
Status: ENROLLING_BY_INVITATION
Conditions: Borderline Personality Disorder|Suicide and Self-harm
Interventions: BEHAVIORAL: Brief 4-session intervention for borderline personality disorder|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4
Status: COMPLETED
Conditions: Metastatic Urothelial Cancer and Other Malignant Solid Tumors
Interventions: DRUG: enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of POL6014 in Patients With CF
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: POL6014|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Moxonidine for Prevention of Post-ablation AFib Recurrences
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Moxonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Wounds and Injuries|Surgery--Complications
Interventions: DRUG: Cefuroxime (750mg) I.V|PROCEDURE: Colonic Surgery|DRUG: Cefuroxime 750mg oral|DRUG: Metronidazole 250 MG Oral Tablet [Flagyl]|DRUG: Metronidazole 1 g Intravenous|DRUG: Cefuroxime 1,5 g Intravenous|DRUG: Sodium picosulfate, light magnesium oxide, anhydrous citric acid 10 mg/3.5 g/10.97 g Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paravertebral Block Versus Epidural Anesthesia for Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: PROCEDURE: paravertebral block|PROCEDURE: epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Myofascial Induction Technique Versus a Control Laser
Status: COMPLETED
Conditions: Foot Diseases|Myofascial Pain
Interventions: OTHER: Sham Laser|OTHER: Myofascial Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: SUSPENDED
Conditions: Recurrent Classic Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Brentuximab Vedotin|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol for a Feasibility Cluster Randomised Controlled Trial of a Home-based Depression Care for Older People Delivered by Lay Providers in Nigeria
Status: NOT_YET_RECRUITING
Conditions: Depression in Old Age
Interventions: BEHAVIORAL: emhGAP-Age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Renuvion/J-Plasma for Subdermal Skin Tightening and Contouring of the Upper Arms: Dissection Technique Comparison
Status: TERMINATED
Conditions: Subdermal Skin Tightening
Interventions: PROCEDURE: Renuvion/j-Plasma procedure using blunt dissection technique|PROCEDURE: Renuvion/j-Plasma procedure using ultrasound-guided dissection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Changes in Serum antimüllerian Hormone Levels in Patients 3 and 12 Months After Endometrioma Sclerotherapy
Status: COMPLETED
Conditions: Endometriosis Ovary
Interventions: BIOLOGICAL: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain
Status: COMPLETED
Conditions: Ocular Pain|Dry Eye Syndrome
Interventions: DRUG: SYL1001|DRUG: SYL1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macrophages Effect on Chemoresistance
Status: UNKNOWN
Conditions: the Focus of the Study is Macrophage-induced Chemoresistance in Pancreatic Carcinoma Cells During Chemotherapy.
Interventions: PROCEDURE: taking blood samples from healthy people
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of 'Pentoxifylline and or IgM Enriched Intravenous Immunoglobulin in the Treatment of Neonatal Sepsis'
Status: UNKNOWN
Conditions: Sepsis of the Newborn
Interventions: DRUG: Pentoxifylline, pentaglobin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH)
Status: RECRUITING
Conditions: Infertility, Female
Interventions: DRUG: Pre-treatment with rLH (Luveris 75 IU),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIO 300 Non-Small Cell Lung Cancer Study
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIO 300 Oral Suspension|DRUG: Paclitaxel|DRUG: Carboplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Telesurveillance and Home Cough Assistance for Amyotrophic Lateral Patients (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: telesurveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Cinical and Biological Database in Ovarian, Fallopian Tube and Peritoneal Cancers
Status: RECRUITING
Conditions: Carcinoma, Ovarian Epithelial|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: OTHER: Biological collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil
Status: COMPLETED
Conditions: P Vivax|Malaria, Vivax
Interventions: DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prodromes of Menstrual Staphylococcal Toxic Shock
Status: RECRUITING
Conditions: Toxic Shock Syndrome Staphylococcal
Interventions: OTHER: Identification of symptoms of menstrual staphylococcal toxic shock in last three menstrual period|OTHER: Identification of symptoms of menstrual in control patient in the last three menstrual period
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extended Endoscopic Approaches to Non-malignant Maxillary Sinus Lesions Comparative
Status: UNKNOWN
Conditions: Maxillary Sinus Disease|Approach-Approach Conflict
Interventions: PROCEDURE: endoscopic maxillary mega-antrostomy|PROCEDURE: Endoscopic Modified Medial Maxillectomy|PROCEDURE: Modified endoscopic pre-lacrimal approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract
Status: RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: 68Ga-DOTATATE|DIAGNOSTIC_TEST: Positron Emission Tomography (PET) Scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changes and Associations Between Cervical Range of Motion, Pain, TMJ Range of Motion and Quality of Life in Migraineurs Applying Physical Therapy
Status: COMPLETED
Conditions: Migraine|Temporomandibular Joint Disorders|Myofascial Trigger Point Pain
Interventions: OTHER: Aerobic exercise and exercise for TMJ|OTHER: Aerobic exercise at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Adherence to Prescribing Guidelines for Cholesterol Lowering in Hospitalized Diabetic Patients
Status: COMPLETED
Conditions: Diabetes|Dyslipidemia
Interventions: OTHER: Academic detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Lactobacillus Reuteri Oral Drops|PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Cosmetic Outcomes in Adhesive Strip Versus Suture Repair for Simple Facial Lacerations
Status: NOT_YET_RECRUITING
Conditions: Facial Laceration
Interventions: PROCEDURE: Laceration repair with adhesive strips|PROCEDURE: Laceration repair with sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-body Resiliency Intervention for Fear of Cancer Recurrence
Status: COMPLETED
Conditions: Cancer|Coping Skills|Coping Behavior
Interventions: BEHAVIORAL: IN FOCUS|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Intercostal Nerve Stimulation in Spinal Cord Injury
Status: WITHDRAWN
Conditions: Neuropathic Pain|SCI - Spinal Cord Injury
Interventions: DEVICE: TINS Active protocol|DEVICE: Sham protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrating Mindfulness-Based Skills Training Into Brief Outpatient Treatment for Substance Abusing Youth
Status: COMPLETED
Conditions: Substance Abuse|Drug Addiction
Interventions: BEHAVIORAL: MI Alone or Plus Mindfulness-Based Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacogenomics Study of Safety and Efficacy of Enalapril or Enalapril-Folic Acid Therapy in Hypertensive Patients.
Status: UNKNOWN
Conditions: Enalapril Adverse Reaction|Pharmacogenomics|Stroke
Interventions: GENETIC: detection of genotype
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Palliative Care Health Literacy Education and QOL Compared to Usual Care
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: BEHAVIORAL: Get Palliative Care: four educational learning module videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I/IIa Study of UV1 Vaccination in Patients With Non Small Cell Lung Cancer.
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: UV1 synthetic peptide vaccine and GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: MORAb-003 (farletuzumab)|DRUG: 0.9% Saline|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Spinal Surgery Protocol Versus Conventional Care in Non Insulin Diabetic Patients ( ERAS )
Status: COMPLETED
Conditions: ERAS|Surgery|Non Insulin Dependent Diabetes Mellitus|Lumbar Spine Disease
Interventions: OTHER: ERAS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Generalization of Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Problem-Solving Training|BEHAVIORAL: Work-Related Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Trastuzumab and Pertuzumab in Treating Patients With Unresectable Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Trastuzumab
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: pertuzumab|BIOLOGICAL: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety, Tolerability and Pharmacokinetics(PK) of DZD9008 and the Effect of Low-fat Meal on PK of DZD9008 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DZD9008|DRUG: Placebo|DRUG: DZD9008|DRUG: DZD9008
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ginger in Treating Nausea in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DIETARY_SUPPLEMENT: ginger|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Infection|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: amphotericin B deoxycholate|DRUG: nystatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between the Neuromuscular Blockade Onset Monitoring and the Expectation of a Fixed Delay After Curarization on the Quality of Laryngoscopy During Intubation in Elective Surgery (MONITURARE)
Status: COMPLETED
Conditions: Laryngoscopy|Anesthesic Aduction|Neuromuscular Blockade|Monitoring
Interventions: DEVICE: Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bacterial Composition and Recurrent Cystitis in Postmenopausal Women After Treatment With Lactobacilli.
Status: RECRUITING
Conditions: Cystitis Recurrent|Lactobacillus Infection
Interventions: DIETARY_SUPPLEMENT: FEMIDUR®|OTHER: Placebo Z Cap V-3 Pla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT