pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7-Valent Conjugate Vaccine in Healthy 12-Month-Old Children (V251-067)
Status: COMPLETED
Conditions: Hepatitis A Virus
Interventions: BIOLOGICAL: Comparator: VAQTA™ (Hepatitis A vaccine)|BIOLOGICAL: Comparator: ProQuad™ (Measles, Mumps, Rubella and Varicella vaccine)|BIOLOGICAL: Comparator: Prevnar™ (Pneumococcal 7-Valent Conjugate vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-Inflammatory Actions of Valsartan in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Hypertension|Type 2 Diabetes Mellitus|Coronary Artery Disease
Interventions: DRUG: Valsartan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Based Manual in Sedentary Prediabetic Population
Status: COMPLETED
Conditions: PreDiabetes
Interventions: OTHER: Exercise Based Manual (Supervised)|OTHER: Exercise Based Manual (Home Based)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pragmatic Trial of Dietary Programs in People With Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Frequent Patient Interaction|BEHAVIORAL: Timing Restriction|DEVICE: LoseIt! Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pancreatic Pseudocysts by Endoscopic Ultrasound-guided Drainage
Status: RECRUITING
Conditions: Pancreatic Pseudocyst|Drainage
Interventions: PROCEDURE: Pancreatic pseudocyst drainage with a plastic or self-expandable metallic stent (SEMS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodynamic Changes and Propofol Pharmacokinetic Variation During Anesthesia Induction and Knee-chest Positioning
Status: COMPLETED
Conditions: Hemodynamic Instability|Anesthesia|Surgery
Interventions: DRUG: Propofol reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Horyzons: Implementation and Integration in Clinical Practice
Status: RECRUITING
Conditions: Schizophrenia|Schizophreniform Disorders|Schizoaffective Disorder|Unspecified or Other Psychotic Disorders
Interventions: DEVICE: Horyzons USA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTH - Preemptive Treatment for Herpesviridae
Status: COMPLETED
Conditions: Viral Pneumonia
Interventions: DRUG: Aciclovir|DRUG: Ganciclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Insomnia on Pain in HIV
Status: RECRUITING
Conditions: HIV|Insomnia
Interventions: DIAGNOSTIC_TEST: Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised|DIAGNOSTIC_TEST: Resmed ApneaLink Air device (Resmed, San Diego, CA).|OTHER: Quantitative Sensory testing (QST)|DIAGNOSTIC_TEST: OraQuick Advance Rapid HIV 1/2 Swab test|DIAGNOSTIC_TEST: Cluster of Differentiation 4 (CD4) and Viral load
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Dasatinib|DRUG: Leuprolide Acetate (LHRH Analogue)|PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS)
Status: COMPLETED
Conditions: Unstable Angina|Myocardial Infarction|Acute Disease
Interventions: DRUG: Angiomax (bivalirudin) anticoagulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2450 Injection and Anlotinib Hydrochloride Capsules to Treat Triple Negative Breast Cancer (TNBC)
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: TQB2450 Injection and Anlotinib Hydrochioride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Web-based Psychoeducation Programme With a Motivational AI Chatbot on Covid-19 Vaccine Hesitancy
Status: COMPLETED
Conditions: Vaccine Hesitancy|COVID-19
Interventions: BEHAVIORAL: AI-driven Vaccine Communicator|BEHAVIORAL: Self-learning of COVID-19 vaccine knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)
Status: COMPLETED
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DRUG: Levetiracetam 62.5mg|DRUG: Levetiracetam 125mg|DRUG: Levetiracetam 250mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Boosting Strategies After Vaccination With ALVAC-HIV and AIDSVAX® B/E
Status: UNKNOWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV|BIOLOGICAL: AIDSVAX B/E|BIOLOGICAL: ALVAC-HIV Placebo|BIOLOGICAL: AIDSVAX B/E Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
Status: COMPLETED
Conditions: Headache|Migraine
Interventions: OTHER: Carbon monoxide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effectiveness of Preemptive Paracetamol and Ibuprofen in Acute Postoperative Pain
Status: UNKNOWN
Conditions: Acute Pain|Postoperative Pain
Interventions: DRUG: Paracetamol|DRUG: Ibuprofen 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stripping Massage on Rhomboid Major and Minor Active Trigger Points in Upper Thoracic Pain
Status: RECRUITING
Conditions: Upper Thoracic Pain Due to Active Trigger Points
Interventions: OTHER: stripping massage + conventional therapy|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protective Mechanical VENTilation Strategy in Patients Undergoing CARDiac Surgery
Status: UNKNOWN
Conditions: Pulmonary Complications|Cardiac Surgery
Interventions: OTHER: A comprehensive perioperative mechanical ventilation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Exercise on Glycaemic Response of Low or High Glycaemic Index Meals
Status: COMPLETED
Conditions: Glycaemic Response
Interventions: OTHER: High glycaemic index meal and exercise|OTHER: High glycaemic index meal and rest|OTHER: Low glycaemic index meal and exercise|OTHER: Low glycaemic index meal and rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Two-Week Study of an Anticavity Low pH Mouthwash
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Listerine Experimental Mouthwash|DRUG: Colgate Cavity Protection Toothpaste|DRUG: Listerine Total Care Zero|OTHER: Listerine Cool Mint Zero
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia
Status: RECRUITING
Conditions: Gestational Trophoblastic Tumor|Gestational Trophoblastic Neoplasia|Stage I Gestational Trophoblastic Tumor|Stage II Gestational Trophoblastic Tumor|Stage III Gestational Trophoblastic Tumor|Invasive Mole|Choriocarcinoma
Interventions: DRUG: Methotrexate|DRUG: Leucovorin|DRUG: Dactinomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Phototherapy Using Neolight Skylife Versus Standardized Phototherapy for Hyperbilirubinemia in Newborns
Status: COMPLETED
Conditions: Jaundice, Neonatal|Neonatal Hyperbilirubinemia|Neonatal Disorder
Interventions: DEVICE: Skylife|DEVICE: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bufei Yishen Prescription on Patients With Frequent AECOPD in Stable Stage
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Bufei Yishen Prescription Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-Fosgonimeton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single IV Dose of GLYX-13 in Patients With Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: GLYX-13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expressive Helping for Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Stem Cell Transplantation|Hematologic Malignancy
Interventions: BEHAVIORAL: Expressive Helping|BEHAVIORAL: Factual Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib|BIOLOGICAL: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GV1001 Subcutaneous(SC) for the Treatment of Progressive Supranuclear Palsy (PSP)
Status: RECRUITING
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: GV1001 Placebo|DRUG: GV1001 0.56mg|DRUG: GV1001 1.12mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics
Status: COMPLETED
Conditions: Kidney Transplant Patients
Interventions: DRUG: Combined with voriconazole|DRUG: Combined with caspofungin|DRUG: Tacrolimus-alone treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Deep Brain Stimulation in Patients With Treatment Resistant Major Depression
Status: RECRUITING
Conditions: Treatment-resistant Depression
Interventions: DEVICE: Vercise GEVIA deep brain stimulation (DBS) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases.
Status: COMPLETED
Conditions: Chronic Infectious Disease|Chronic Skin Disease|Mental Disorders|Psoriasis|Hidradenitis Suppurativa|Atopic Dermatitis|Hiv|HBV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn How Well the Drug Vericiguat Works and How Safe it is Under Real World Conditions in Indian Participants After Worsening of a Long-term Heart Condition in Which the Left Side of the Heart Does Not Pump Blood as Well as it Should (Chronic Heart Failure With Reduced Ejection Fraction)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Heart Failure With Reduced Ejection Fraction|Worsening Heart Failure
Interventions: DRUG: Vericiguat (Verquvo, BAY1021189)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: BAF312|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the External Fastening System for Temporary Active Fixation Pacemakers (TEMPACE)
Status: RECRUITING
Conditions: Arrythmia|Bradycardia
Interventions: DEVICE: KronoSafe® System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers
Status: COMPLETED
Conditions: Pancreatic Cancer|Biliary Cancer
Interventions: DRUG: gemcitabine|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors Cancer
Interventions: DRUG: Osimertinib|DRUG: Nivolumab|DRUG: Telisotuzumab vedotin|DRUG: Telisotuzumab vedotin|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Comparator: atorvastatin|DRUG: Comparator: Placebo|DRUG: Comparator: ezetimibe|DRUG: Comparator: Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Propofol and Desflurane on Nucleic Acid of Liver Circulating Tumor
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Desflurane Adverse Reaction|Propofol Adverse Reaction|Circulating Tumor Cells
Interventions: DRUG: Desﬂurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Self-Myofascial Stretching on Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Patients With Stage I and II Carpal Tunnel Syndrome
Interventions: OTHER: self-myofascial stretching|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Function and Imaging Assessments for G1961E-associated Stargardt Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Stargardt Disease|Stargardt Disease 1|Fundus Flavimaculatus|Macular Degeneration, Stargardt|Macular Dystrophy With Flecks, Type 1
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of Arterio Venous Access Stage (AVAS) Classification
Status: ACTIVE_NOT_RECRUITING
Conditions: Arteriovenous Graft|Arteriovenous Fistula|Dialysis Access Malfunction|Kidney Failure|Dialysis Related Complication
Interventions: OTHER: AVAS Classification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Control Trial for Preventative Scar Management
Status: COMPLETED
Conditions: Hypertrophic Scarring
Interventions: PROCEDURE: Silicone Only Therapy (SOT)|PROCEDURE: Silicone Pressure Garment Therapy (SPGT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stenting of Venous Sinus Stenosis for Medically Refractory Idiopathic Intracranial Hypertension
Status: UNKNOWN
Conditions: Idiopathic Intracranial Hypertension
Interventions: PROCEDURE: Stenting of the venous sinus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reiki on Symptom Control and Quality of Life in Breast Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Symptoms and Signs|Quality of Life
Interventions: PROCEDURE: Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Single-Center Evaluation of SureForm™ Staplers in Robotic-assisted Colorectal Procedures
Status: COMPLETED
Conditions: Benign Colon Tumor|Malignant Colorectal Tumor|Benign Colorectal Neoplasm
Interventions: PROCEDURE: Colorectal resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Ketamine|BEHAVIORAL: Exposure and Response Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture
Status: WITHDRAWN
Conditions: Hip Fractures|Intertrochanteric Fractures
Interventions: DRUG: EXPAREL|DRUG: Ropivacaine|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Status: NOT_YET_RECRUITING
Conditions: Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Interventions: DRUG: Ketamine in PECS block versus topical wound instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluate the Effects of Dapagliflozin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type-2 Diabetes|Oral Antidiabetics
Interventions: DRUG: Dapagliflozin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics of MK-8876 in Participants With Hepatitis C Infection (MK-8876-003)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MK-8876
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Resin Composite Posterior Restorations Using Modeling Resin Insertion Technique in Class I Lesions
Status: NOT_YET_RECRUITING
Conditions: Class I Composite Restorations
Interventions: PROCEDURE: Modeling Resin Insertion Technique|PROCEDURE: Conventional resin composite Incremental Placement Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sugammadex in Renal Diseased Patients
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Neuromuscular Blockade
Interventions: DRUG: Sugammadex (4 mg/Kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Status: COMPLETED
Conditions: Carcinoma, Renal Cell, Advanced|Lymphoma, Mantle-Cell|Gastrointestinal Stroma Tumors
Interventions: DRUG: Temsirolimus|DRUG: Temsirolimus|DRUG: Sunitinib|DRUG: Sunitinib|DRUG: Axitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Results in Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy
Status: RECRUITING
Conditions: Colon Cancer|Colon Neoplasm|Malignant Neoplasm|Colon Neoplasia|Colon Neoplasm, Malignant
Interventions: PROCEDURE: Intracorporeal anastomosis|PROCEDURE: Extracorporeal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Cardiopulmonary Resuscitation
Status: UNKNOWN
Conditions: Heart Arrest|Ventricular Fibrillation|Ventricular Flutter|Ventricular Tachycardia
Interventions: DIAGNOSTIC_TEST: TSH determination|DIAGNOSTIC_TEST: FT4 determination|DIAGNOSTIC_TEST: FT3 determination|DIAGNOSTIC_TEST: SPINA-GT|DIAGNOSTIC_TEST: SPINA-GD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Efficacy and Safety of Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Docetaxel-PM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Anemia|B-Cell Prolymphocytic Leukemia|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma|Hairy Cell Leukemia|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma|Richter Syndrome
Interventions: DRUG: Entospletinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Obinutuzumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma|RAS Wild Type|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|BIOLOGICAL: Cetuximab|DRUG: Irinotecan|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Two Dapivirine (TMC120) Vaginal Gels in the United States
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: DRUG: dapivirine 4789|DRUG: dapivirine gel 4759|DRUG: Drug placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Toddler Overweight Prevention Study Among Low-Income Families
Status: COMPLETED
Conditions: Overweight|Obesity|Depression
Interventions: BEHAVIORAL: Maternal Physical Activity and Nutrition|BEHAVIORAL: Parenting|BEHAVIORAL: Child Safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: High frequency chest wall oscillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of GBR in Augmentation of Horizontally Atrophic Maxillary Ridge Using Collagen Membrane Versus Using Titanium Mesh
Status: UNKNOWN
Conditions: Horizontal Ridge Deficiency
Interventions: PROCEDURE: titanium mesh|PROCEDURE: collagen membrane (Sausage technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of LEO 80185 Topical Suspension in Adolescent Subjects (Aged 12 to 17) With Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: LEO 80185 (Taclonex® Scalp topical suspension/Xamiol® gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Study of Amish and Mennonite Patients With CNTNAP2 Mutations
Status: TERMINATED
Conditions: Schizophrenia
Interventions: RADIATION: PET/SPECT Scan|DEVICE: MRI Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess the Safety and Efficacy of Individually Tailored Prophylaxis With Human-cl rhFVIII in Patients With Severe Haemophilia A
Status: COMPLETED
Conditions: Severe Haemophilia A
Interventions: BIOLOGICAL: Human-cl rhFVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Of Molecular Targets In Mild To Severe Asthmatics And Healthy Subjects
Status: TERMINATED
Conditions: Asthma
Interventions: PROCEDURE: Bronchoscopsy|PROCEDURE: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The EPOCH Study (Eplerenone on Top of ACE Inhibition in Chronic Kidney Disease Patients With Hypertension)
Status: UNKNOWN
Conditions: CKD II-III
Interventions: DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Turmeric, Black Seeds, Flaxseed and Medicago Sativa in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib in Recurrent or Metastatic Nasopharyngeal Carcinoma Patients After Failure of no Less Than Second-line Therapy
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)
Status: UNKNOWN
Conditions: Cancer, All Types|Cancer of Liver|Cancer of Stomach|Cancer of Head and Neck|Cancer of Rectum|Cancer of Kidney|Cancer of Esophagus|Cancer of Colon|Cancer Skin|Cancer of Cervix|Cancer, Metastatic|Cancer of Larynx|Cancer of Neck|Cancer of Lung|Cancer of Brain and Nervous System|Cancer of Vulva, Disseminated|Cancer of Pancreas|Sarcoma|GIST|Small-cell Lung Cancer|Adenocarcinoma Lung|Cancer of Prostate|Cancer, Advanced|Adrenal Cancer|Testicular Cancer|Uterine Cancer|Bronchoalveolar Cell Lung Cancer|Cancer Unknown Primary|Glioblastoma Multiforme|Oligodendroglioma|Breast Cancer|Renal Cell Carcinoma|Hepatocellular Carcinoma|Cholangiocarcinoma|Squamous Cell Carcinoma|Transitional Cell Carcinoma|Cancer, Other|Cancer, Anal|Melanoma|Cancer, Bile Duct|Cancer, Bladder|Cancer Cords Vocal|Cancers Cell Neuroendocrine|Cancer Differentiated Poorly|Cancer, Anaplastic Thyroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Injection Site Tolerability of Multiple Dose Treatment With Long-acting Injectable Risperidone Administered Via Deltoid Muscle in Chronic Schizophrenia Patients.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone long-acting injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AD-214-02|DRUG: Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dental Intervention Plan for Chronic Kidney Disease Patients Awaiting or With Kidney Transplant
Status: TERMINATED
Conditions: Chronic Kidney Disease|Chronic Periodontitis, Generalized, Moderate
Interventions: PROCEDURE: dental intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility And Safety Study Of rhBMP-2/CPM For Hip Fractures
Status: COMPLETED
Conditions: Fractures
Interventions: DRUG: rhBMP-2/CPM|DRUG: rhBMP-2/CPM|OTHER: surgical intervention alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Depression and Anxiety Treatment
Status: COMPLETED
Conditions: Smoking|Anxiety Disorders|Depression Disorders
Interventions: DRUG: Nicotine Patch|BEHAVIORAL: Depression and Anxiety Smoking Cessation Treatment|BEHAVIORAL: Educational-Support Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative User Experiences With BD Nano™ PRO 4mm x 32G Extra Thin Wall Pen Needle vs Three Commercially Available Pen Needles
Status: COMPLETED
Conditions: Diabetes
Interventions: DEVICE: BD Nano™ PRO|DEVICE: 33G Artsana Insupen Extr3me|DEVICE: 34G Artsana Insupen Extr3me|DEVICE: Simple Diagnostics Comfort EZ™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Vinorelbine|DRUG: Trastuzumab|DRUG: Avelumab|DRUG: Utomilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denosumab vs Alendronate After Vertebroplasty
Status: RECRUITING
Conditions: Denosumab Allergy
Interventions: DRUG: Denosumab|DRUG: Alendronate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Right Ventricular Function in Young Adults Born Preterm
Status: COMPLETED
Conditions: Infant,Premature
Interventions: PROCEDURE: Pulmonary Function Testing|PROCEDURE: Electrocardiogram|PROCEDURE: Cardiac Magnetic Resonance Imaging|DRUG: Metoprolol|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimizing Glucocorticoid Administration in Patients With Proliferative Lupus Nephritis
Status: RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Rituximab|DRUG: Mycophenolate Mofetil|DRUG: Cyclophosphamide|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis
Status: NOT_YET_RECRUITING
Conditions: Sarcoidosis, Pulmonary
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: PF-04878691 3mg|DRUG: PF-04878691 6mg|DRUG: PF-04878691 9mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DPP-IV Inhibition Prior to Development of Diabetes in Patients With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Chronic Pain Self-Management in Clinic or Community for Low-Income Hispanics
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Community-based pain self-management|BEHAVIORAL: Clinic-based pain self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Giving an HIV Vaccine (Remune) to HIV-Positive Patients Receiving an Anti-HIV Drug Combination
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)|BIOLOGICAL: HIV-1 Immunogen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Well-differentiated Neuroendocrine Tumors
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002
Status: COMPLETED
Conditions: Natural Blood and Blood Product Toxicity
Interventions: BIOLOGICAL: Erythropoietin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine-Impregnated Sponge Dressing: A Clinical Trial
Status: UNKNOWN
Conditions: Catheter-Related Infections
Interventions: DEVICE: chlorhexidine-gel-impregnated dressing|DEVICE: Polyurethane film dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 1.75 mg Formulation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: zolpidem hemitartarate 1.75 mg - Sequency 1|DRUG: zolpidem hemitartarate 1.75 mg - Sequency 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Status: COMPLETED
Conditions: Pain, Postoperative|Phimosis|Paraphimosis|Balanitis
Interventions: DRUG: Bupivacaine|DRUG: Sevoflurane|DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Syncope by Cardiac Pacing in Patients With Bifascicular Block
Status: COMPLETED
Conditions: Bifascicular Block|Syncope
Interventions: DEVICE: DDD60 (INSIGNIA® pacing systems Guidant (Boston Scientific)|DEVICE: DDD60 (INSIGNIA® pacing systems Guidant (Boston Scientific)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of SIBP-A13 Injection in the Treatment of Advanced Malignant Solid Tumor Patients.
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: SIBP-A13 formulation for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cisplatin|DRUG: everolimus|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Cord Blood-derived CAR-NK Cells Targeting CD19 in the Treatment of Refractory/Relapsed B-cell NHL
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: anti-CD19 CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentostatin, Cyclophosphamide, and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia or Other B-cell Cancers
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: pentostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior or Erector Spinae Block for Hybrid Arrhythmia Ablation Surgery
Status: RECRUITING
Conditions: Arrhythmia
Interventions: DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus Syndrome
Status: TERMINATED
Conditions: Sick Sinus Syndrome
Interventions: DEVICE: AAIR/DDDR pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy & Safety of Ursoplus Capsules vs. UDCA vs. Placebo Among Chronic Liver Disease Patients
Status: RECRUITING
Conditions: Chronic Liver Disease
Interventions: DRUG: Ursoplus|DRUG: UDCA 250mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: OTHER: Acute Intermittent Hypoxia (AIH)|BEHAVIORAL: Task specific Airway Protection Training|OTHER: Sham AIH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gallium Ga 68-DOTATATE PET/CT in Diagnosing Patients With Metastatic Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v7
Interventions: PROCEDURE: CT (Computed Tomography)|DRUG: Gallium Ga 68-DOTATATE|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture Ribs
Status: RECRUITING
Conditions: Fracture Rib
Interventions: PROCEDURE: thoracic paravertebral block|PROCEDURE: rhomboid intercostal and subserratus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanized Instrumentation for Endodontic Treatment of Primary Teeth
Status: COMPLETED
Conditions: Endodontic Treatment of Primary Teeth
Interventions: PROCEDURE: Manual instrumentation|PROCEDURE: Reciprocating Instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of TRK-100STP
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TRK-100STP (BERASUS LA)|DRUG: AST-120 (Kremezin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of HU6
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: HU6 450 mg Tablet|DRUG: HU6 150 mg Capsules x 3 (Total dose = 450 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg)
Status: UNKNOWN
Conditions: Endometriosis|Dysmenorrhea|Dyspareunia
Interventions: DRUG: Norethindrone Acetate (NA)|DRUG: GnRH Agonist (Lupron Depot)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Regulation of Leukocyte Function
Status: COMPLETED
Conditions: FPP|Fermented Papaya Preparation|Supplements|Diabetic Wound|Healing Wound
Interventions: DIETARY_SUPPLEMENT: FPP supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Sexual Dysfunction and Infertility|Sexuality
Interventions: OTHER: communication intervention|OTHER: counseling intervention|OTHER: nutrition intervention|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis|Sleep Disturbance
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol)
Status: TERMINATED
Conditions: Bone Demineralization Lesions in the Injured Marrow
Interventions: DRUG: Zoledronic acid|DRUG: NA Cl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients
Status: UNKNOWN
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Non ATG Conditioning regimen|DRUG: GVHD Prophylaxis|PROCEDURE: Allogenic Stem Cell Transplantation|DRUG: ATG conditioning regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Correlates of Nocebo Effects on Pain
Status: COMPLETED
Conditions: Chronic Pain Syndrome|Chronic Pain, Psychogenic|Chronic Pain|Hyperalgesia
Interventions: BEHAVIORAL: Baseline pain stimulations|BEHAVIORAL: Conditioning|BEHAVIORAL: Evocation|OTHER: Electroencephalography (EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome.
Status: UNKNOWN
Conditions: Coronary Artery Bypass|Myocardial Reperfusion Injur|Ischemic Preconditioning, Myocardial|Ischemic Postconditioning
Interventions: PROCEDURE: Remote Ischemic Preconditioning with Postconditioning|PROCEDURE: Sham RIPC procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Robotic Versus Laparoscopic Assisted Radical Gastrectomy for Advanced Siewert II/III AEG
Status: ENROLLING_BY_INVITATION
Conditions: Esophagogastric Junction Adenocarcinoma
Interventions: PROCEDURE: Robotic Assisted AEG Radical Gastrectomy|PROCEDURE: Laparoscopic Assisted AEG Radical Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preparing for the Final Phase of Hepatitis C Elimination. Cairns Final 30%
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DEVICE: Xpert HCV Viral load finger stick point of care test (Cepheid)|DRUG: Epclusa 400Mg-100Mg Tablet|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Efficacy And Safety Of Anidulafungin Vs. Fluconazole In The Treatment Of Patients With Candidemia And/Or Other Forms Of Invasive Candidiasis
Status: TERMINATED
Conditions: Candidemia
Interventions: DRUG: Anidulafungin/Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: