pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: TDF Intravaginal Ring|DRUG: Placebo Intravaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Study of PCV and PCV-VG in Patients Undergoing Bariatric Surgery
Status: UNKNOWN
Conditions: Bariatric Surgery|Mechanical Ventilation
Interventions: DEVICE: PCV-VG, PEEP5cmH₂O|DEVICE: PCV, PEEP5cmH₂O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of QAX576 in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: QAX576|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache
Status: COMPLETED
Conditions: Headache|Cephalgia|Migraine
Interventions: PROCEDURE: Osteopathic Manipulative Treatment (OMT)|PROCEDURE: Light touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Ex vivo Expanded Human Autologous Polyclonal Regulatory T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Milademetan in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Milademetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Use of a 3D Scanner Application on a Smartphone to Mold Garchois Orthotic Device in Neuromuscular Diseases Patients With Scoliosis
Status: COMPLETED
Conditions: Neuromuscular Diseases|Scoliosis
Interventions: DEVICE: Plaster cast|DEVICE: 3D Scanning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: Intrathecal morphine sulfate (ITM)|DRUG: Bupivacaine hydrochloride|DRUG: ropivacaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects.
Status: COMPLETED
Conditions: Ascites
Interventions: DRUG: recombinant human albumin injection|DRUG: Placebo|DRUG: human albumin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Status: COMPLETED
Conditions: Hand Injuries/Disease Requiring Surgery to the Hand
Interventions: DRUG: Oxygen|DRUG: Medical air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphine-sparing Effect of Intravenous Paracetamol for Post-operative Pain Management Following Laparoscopic Gastric Banding in Morbidly Obese Patients
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SA55 Injection Phase II Study in the Treatment of Mild/Moderate COVID-19 Patients
Status: RECRUITING
Conditions: Infection of Upper Respiratory Tract Caused by 2019-nCoV
Interventions: DRUG: SA55 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Partial Breast Irradiation Utilizing Permanent Breast Seed Implant to Treat Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Partial Breast Irradiation Utilizing Permanent Breast Seed Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kallikrein-kinin (KKS) and Renin-angiotensin-aldosterone System (RAAS) in Primary Aldosteronism
Status: COMPLETED
Conditions: Hyperaldosteronism
Interventions: DRUG: captopril, Losartan (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fixed 100 mg Every Evening of Flibanserin vs Placebo in Premenopausal Women With Hypoactive Sexual Desire Disorder
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: Flibanserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Machine-learning Algorithm to Differentiate Intraoperative Ketamine Dosing Based on Electroencephalographic Density Spectrum Array Analysis
Status: UNKNOWN
Conditions: Electroencephalographic Density Spectrum Array Analysis|Density Spectrum Array|Ketamine|Multimodal General Anesthesia
Interventions: DRUG: Ketamine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of "Quantum-Touch" on Pain, Fear, and Anxiety of the Children
Status: COMPLETED
Conditions: Pain, Acute|Child Behavior|Anxiety and Fear|Venipuncture Site Reaction|Quantum
Interventions: BEHAVIORAL: Quantum touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Olanzapine and Metoclopramide For Treatment Of bReakThrough Emesis
Status: TERMINATED
Conditions: Emesis
Interventions: DRUG: olanzapine|DRUG: metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RIvaroxaban for Stroke Patients With AntiPhospholipid Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Antiphospholipid Syndrome|Systemic Lupus Erythematosus|Stroke|Ischemic Stroke|Brain Ischemia
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Adenosine in the Control of Choroidal Blood Flow During Changes in Ocular Perfusion Pressure.
Status: COMPLETED
Conditions: Ocular Physiology|Microcirculation
Interventions: DRUG: Adenosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Pain in Emergency Department by Using Veinous Blood Gas Instead of Arterious Blood Gas
Status: COMPLETED
Conditions: Acid Base Disorder
Interventions: DIAGNOSTIC_TEST: Arterial blood gas|DIAGNOSTIC_TEST: Veinous blood gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Single and Multiple Doses of ALS-008176 in Healthy Volunteers
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: ALS-008176|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients With Intravenous Infusion of Magnesium Sulfate
Status: WITHDRAWN
Conditions: Death, Sudden, Cardiac|Coma
Interventions: DEVICE: Cooling with ThermoSuit with Magnesium Sulfate Infusion|DEVICE: Cooling with ThermoSuit with Normal Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parsaclisib in Combination With CHOP in Participants With Previously Untreated PTCL
Status: NOT_YET_RECRUITING
Conditions: PI3Kδ Inhibitor|Parsaclisib|CHOP|PTCL
Interventions: DRUG: Parsaclisib|DRUG: CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Trivalent Influenza Vaccine in Pregnant and Nonpregnant HIV Uninfected Women
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function
Status: RECRUITING
Conditions: Obesity|Metabolic Syndrome
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Recombinant Protein (Ecallantide) to Reduce Blood Loss During Primary Coronary Bypass Grafting or Valve Repair/Replacement
Status: TERMINATED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Ecallantide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ACT-541468|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine-fentanyl VS Fentanyl for Analgosedation in SICU
Status: COMPLETED
Conditions: Critically Ill|Pain, Postoperative
Interventions: DRUG: Ketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Implantationof Black Diaphragm Intraocular Lens in Complete Aniridia and Aphakia Due to Posttraumatic Eye Rupture
Status: COMPLETED
Conditions: Aphakia Due to Trauma|Eye; Rupture, Traumatic, With Loss of Intraocular Tissue|Aniridia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Focused Registry to Document the Use of the Short- or Long-stemmed Radial Head Prosthesis (RHP)
Status: WITHDRAWN
Conditions: Fracture of the Radial Head Which is Not Amendable to an Adequate Osteosynthesis|Post-traumatic Deformity or Arthroses|Failed Open Reduction Internal Fixation (ORIF) of a Radial Head Fracture|Failed Conservative Radial Head Fracture Treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cost-effectiveness, Impact of a Workplace-based Intervention to Reduce Occupational Sitting Time in Office-based Workers
Status: NOT_YET_RECRUITING
Conditions: Physical Inactivity|Sedentary Behavior|Occupational Diseases|Physical Activity
Interventions: BEHAVIORAL: ISKE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: UCN-01 and Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Compliance and Tolerance to Oral AntiBiotherapy in Osteoarticular Infections (OTABIO)
Status: RECRUITING
Conditions: Drug-Related Side Effects and Adverse Reactions|Treatment Adherence and Compliance
Interventions: OTHER: Tolerance and adherence to oral antibiotics in patients managed for BJI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Anal Fissure by Activated Human Macrophages
Status: UNKNOWN
Conditions: Biological Therapy for Chronic Anal Fissure|Treatment by Biological Factors - Activated Macrophages|Interventional Study
Interventions: DRUG: Local injection of activated macrophages to anal fissure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of MRE0094 to Treat Chronic, Neuropathic, Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Foot Ulcer, Diabetic|Diabetes Complications
Interventions: DRUG: MRE0094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Glycopyrrolate on Nausea and Vomiting After ERCP Operation
Status: COMPLETED
Conditions: Nausea and Vomiting
Interventions: DRUG: Glycopyrrolate|DRUG: Anisodamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Effects Of GW856553 On Endothelial Function/Vascular Compliance In Subjects With Dyslipidaemia.
Status: COMPLETED
Conditions: Healthy Subjects|Dyslipidaemias|Dyslipidaemia
Interventions: DRUG: GW856553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prexasertib (LY2606368), Cytarabine, and Fludarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia|Recurrent Acute Myeloid Leukemia|Recurrent High Risk Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory High Risk Myelodysplastic Syndrome
Interventions: DRUG: Cytarabine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Prexasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: University Student Intervention to Increase Organ Donation
Status: COMPLETED
Conditions: Organ Donation|Health Behavior
Interventions: BEHAVIORAL: HRSA Video Intervention|BEHAVIORAL: PI Video Intervention|BEHAVIORAL: CDC Health Website Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: ESG vs LSG: Short-term Nutritional Outcomes
Status: COMPLETED
Conditions: Endoscopic Sleeve Gastroplasty|Laparoscopic Sleeve Gastrectomy|Obesity
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|PROCEDURE: Endoscopic sleeve gastroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: oxaliplatin|DRUG: fluorouracil|DRUG: leucovorin|PROCEDURE: External beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Insulin Inhalation Powder in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Injectable insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Combined With Docetaxel for Advanced Non-Small Cell Lung Cancer（ALTER-L034）
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Hydrochloride plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Suppression of Ovulation and Pharmacokinetics of Medroxyprogesterone Acetate Following Administration of TV-46046 in Women With Ovulatory Cycle
Status: COMPLETED
Conditions: Pregnancy|Contraception
Interventions: DRUG: TV-46046 - 400 mg/mL|DRUG: TV-46046 - 200 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase II Pilot Study of Visudyne® Photodynamic Therapy (PDT) (Low and Very Low Fluence) Combined With Bevacizumab.
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Verteporfin Photodynamic Therapy (Low Fluence) and bevacizumab|DRUG: Verteporfin Photodynamic Therapy (Very Low Fluence) and bevacizumab|DRUG: Verteporfin Photodynamic Therapy (SHAM) and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Surgery
Interventions: DRUG: Amino Acids|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture
Status: COMPLETED
Conditions: Femoral Fractures
Interventions: DRUG: Tranexamic Acid plus standard of care|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Group-based Lifestyle Medicine Intervention and CBT on Depressive Symptoms
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Lifestyle medicine intervention|BEHAVIORAL: Cognitive-behavioral therapy for depression (CBT-D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Imiquimod in Treating Patients With Grade 3 Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition|HPV Disease|Human Papilomavirus
Interventions: BIOLOGICAL: TA-HPV|BIOLOGICAL: pNGVL4a-Sig/E7(detox)/HSP70 DNA vaccine|DRUG: imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STATIN: Web-based Investigation of Side Effects
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Atorvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Brace Versus Casting in Pediatric Low Risk Ankle Fractures
Status: COMPLETED
Conditions: Ankle Fracture
Interventions: DEVICE: Below knee walking cast|DEVICE: Removable ankle brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Titanium Nitride Oxide Coated Stents and Paclitaxel Eluting Stents for Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Titan stent and Taxus-Liberte stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time to Clearance of Chlamydia Trachomatis and Neisseria Gonorrhoeae RNA After Treatment: a Prospective Cohort Study
Status: RECRUITING
Conditions: Chlamydia Trachomatis|Neisseria Gonorrhoeae|Uncomplicated Infections
Interventions: DIAGNOSTIC_TEST: Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) NAAT(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of the LUM Imaging System for Detection of Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer|Neoplasm, Residual
Interventions: COMBINATION_PRODUCT: LUM Imaging System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation
Status: COMPLETED
Conditions: Congenital Disorders of Glycosylation
Interventions: DIETARY_SUPPLEMENT: D-Galactose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol
Status: COMPLETED
Conditions: Atrial Septal Defect|Ventricular Septal Defect|Atrioventricular Septal Defect
Interventions: DRUG: Intravenous L-Citrulline|DRUG: Placebo of Intravenous L-Citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Frozen Shoulder Treatment With Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block
Status: NOT_YET_RECRUITING
Conditions: Frozen Shoulder|Adhesive Capsulitis
Interventions: OTHER: SSNB + IACI|OTHER: Sham SSNB + IACI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Combination With CHEP in Patient With PTCL
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, T-Cell, Peripheral
Interventions: DRUG: Adcetris 50 MG Injection|DRUG: Endoxan|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Prednisone tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of 177Lu-AB-3PRGD2 in Various Solid Tumors With Integrin αvβ3 Positive Expression
Status: RECRUITING
Conditions: Refractory Solid Tumor
Interventions: DRUG: 177Lu-AB-3PRGD2 radioligand therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Scalp Nerve Block on the Recovery Quality of Parkinson's Patients After Deep Brain Stimulation
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: scalp nerve block combined with intercostal nerve block using 0.5% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors
Status: COMPLETED
Conditions: Chronic Kidney Disease|Diabetic Nephropathy
Interventions: DRUG: Placebo for Atrasentan 0.2 mg/mL solution|DRUG: 0.25 mg Atrasentan QD|DRUG: 0.75 mg Atrasentan QD|DRUG: 1.75 mg Atrasentan QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Formulation Switching Between SC Infliximab and IV Infliximab in Patients With CD
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Infliximab-Dyyb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Cognitive and Behavioral Effects of Eslicarbazepine Acetate and Carbamazepine in Healthy Adults
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Eslicarbazepine|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: HM11260C|DRUG: Placebo|DRUG: Victoza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Ischemic Cardiomyopathy|Dilated Cardiomyopathy|Heart Failure
Interventions: BIOLOGICAL: autologous bone marrow-derived cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Evaluation of the Nighttime Retention of Effect of an Investigational Lubricant Eye Drop (FID 115958D)
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: FID 115958D (lubricant eye drop)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between Two Oral Formulations of Naproxen 500 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Bioequivalency
Interventions: DRUG: Naproxen Tablets, 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics (PK) of Raltegravir in HIV (Human Immunodeficiency Virus)-Infected Children and Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir poloxamer film coated tablet|DRUG: Raltegravir chewable tablet|DRUG: Raltegravir oral granules for suspension (20 mg/mL)|DRUG: Raltegravir poloxamer film coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz)
Status: RECRUITING
Conditions: Hereditary Hemorrhagic Telangiectasia|Epistaxis|Anemia|Nosebleed|HHT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compression Bandages in Upper Limb Lymphedema
Status: COMPLETED
Conditions: Lymphedema
Interventions: DEVICE: Multilayer bandage|DEVICE: Double compression bandage|DEVICE: Cohesive bandage|DEVICE: Adhesive compression bandage|DEVICE: Kinesiotaping bandage|OTHER: Manual lymphatic drainage (MLD) + Intermittent Pneumatic Compression|OTHER: Upper limb exercises|BEHAVIORAL: Educational strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Non-invasive Pursed-lip Breathing Ventilation (PLBV) in Advanced COPD
Status: SUSPENDED
Conditions: COPD
Interventions: DEVICE: Pursed lip breathing ventilation|DEVICE: Standard non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Maternal Heart Sound on Crying Time and Pain Level in Newborns During Heel Blood Collection
Status: COMPLETED
Conditions: Pain|Infant, Newborn, Disease
Interventions: OTHER: Listening the maternal heart sound during the invasive interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: DWP16001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of 50 mg Venlafaxine Hydrochloride Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: VENLAFAXINE TABLETS 50 mg , single dose|DRUG: Effexor® Tablets equivalent to 50 mg venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Veliparib + VX-970 + Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Teneligliptin in Combination With Metformin in Chinese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin 20mg|DRUG: Placebo|DRUG: Metformin ≥ 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temporal Interference Neurostimulation and Addiction
Status: RECRUITING
Conditions: Nicotine Use Disorder|Substance Use Disorders
Interventions: DEVICE: Active TI-NDBS|OTHER: Sham TI-NDBS|DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of CN1 in Combination With CN401 in Adult Patients With Relapsed/Refractory Lymphoid Malignancies
Status: TERMINATED
Conditions: Relapsed Lymphoid Malignancies|Refractory Lymphoid Malignancies
Interventions: DRUG: CN1, 0.5mg/kg and CN401, 400mg|DRUG: CN1, 1mg/kg and CN401, 600mg|DRUG: CN1, 1mg/kg and CN401, 800mg|DRUG: CN1, 3mg/kg and CN401, 800mg|DRUG: CN1, 10mg/kg and CN401, 800mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral CXA-10 Study in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Kidney Injury
Interventions: DRUG: CXA-10|DRUG: CXA-10 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AB Gait Estim Neurophysiology
Status: RECRUITING
Conditions: Gait
Interventions: OTHER: Gait Training|DEVICE: Functional electrical stimulation (FES)|DEVICE: Peripheral electrical stimulation paired with cortical magnetic stimulation pulses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Pharmacokinetic Profile of Udenafil in Healthy Mexican Adults
Status: COMPLETED
Conditions: Erectile Dysfunction|Phosphodiesterase 5 Inhibitor
Interventions: DRUG: Udenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With Minimal Differentiation|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Adult Erythroleukemia|Adult Pure Erythroid Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Tipifarnib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MASCT-I Combined With Apatinib and/or Camrelizumab in the Treatment of Bone and Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Sarcoma
Interventions: COMBINATION_PRODUCT: MASCT-I, Camrelizumab,Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hybrid and Bismuth Quadruple Therapies for Helicobacter Pylori Eradication
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Bismuth quadruple therapy|DRUG: Hybrid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular ("Wet") Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration|Diabetic Macular Edema
Interventions: DRUG: REGN910-3|DRUG: REGN910|DRUG: Intravitreal Aflibercept Injection (IAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Activity at 25% Above the Ventilation Threshold on Appetite and Food Intake in Boys
Status: COMPLETED
Conditions: Healthy Boys With no Emotional, Behavioral or Learning Problems Within a Normal Body Weight
Interventions: OTHER: Dietary Supplement: water with noncalorie sweetener|OTHER: Activity: With noncalorie sweetener or glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy
Status: RECRUITING
Conditions: Metastatic Squamous Cell Carcinoma of the Vulva
Interventions: DRUG: Paclitaxel and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) of the Insula for Treatment of Alcohol Addiction
Status: UNKNOWN
Conditions: Alcohol Addiction
Interventions: OTHER: rTMS 10 Hz targeting the insula|OTHER: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRI Versus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Carcinoma
Interventions: DRUG: Irinotecan|DRUG: 5-fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lucentis for Clinically Significant Macular Edema Secondary to Central Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: ranibizumab|RADIATION: Argon laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|DRUG: Ezetimibe|OTHER: Placebo to Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pimecrolimus Cream 1% in Patients (2 to 11 Years Old) With Mild to Moderate Facial Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Treatment of Rectal Neuroendocrine Tumor(NET) Less Than 10mm
Status: UNKNOWN
Conditions: Rectal Neuroendocrine Tumor
Interventions: PROCEDURE: ESD procedure|PROCEDURE: EMR-C procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Anti-IL-20 in Healthy Volunteers and Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis|Healthy
Interventions: DRUG: anti-IL-20|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department
Status: COMPLETED
Conditions: Low Back Pain, Mechanical
Interventions: DEVICE: Battlefield Acupuncture|DRUG: Acetaminophen|DRUG: Diclofenac|DRUG: Diazepam|DRUG: Hydrocodone|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate ANT-1401 in Crow's Feet
Status: COMPLETED
Conditions: Lateral Canthal Lines|Crows Feet
Interventions: BIOLOGICAL: ANT-1401|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow
Status: TERMINATED
Conditions: Von Hippel-Lindau Syndrome|Renal Cell Carcinoma|Hemangioblastoma
Interventions: DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Percutaneous Screw Fixation and Cementoplasty for Lytic Bone Metastases
Status: RECRUITING
Conditions: Interventional Radiology
Interventions: OTHER: EQ5D (EuroQol 5 Dimensions)|OTHER: Numerical Rating Scale (NRS)|OTHER: evaluated the consumption of analgesics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: COMBINATION_PRODUCT: BT-600|COMBINATION_PRODUCT: BT-600 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Analgesic Method for Postoperative Pain Relief After Cesarean Section: Intraoperative Superior Hypogastric Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Intraoperative superior hypogastric plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate and Compare the PK Profiles of Abaloparatide-SC and Abaloparatide-sMTS in a Cohort of Healthy Men and Healthy Women.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: abaloparatide-sMTS|COMBINATION_PRODUCT: abaloparatide-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ALTO-101 in Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Cognitive Impairment
Interventions: DRUG: ALTO-101|DEVICE: ALTO-101 Transdermal Delivery System|DRUG: Placebo|DEVICE: Placebo Transdermal Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery
Status: RECRUITING
Conditions: Glaucoma|Choroidal Effusions
Interventions: DRUG: Triamcinolone Acetonide 1 ml of 40 mg/mL suspension|OTHER: Sham - Participants will not recieve the Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis Thumb
Interventions: DRUG: Injection of triamcinolone acetonide into the CMC-1 joint|BEHAVIORAL: Multimodal Occupational therapy for CMC-1 joint OA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Drug-eluting Balloon Catheters in the Treatment of Symptomatic Intracranial Atherosclerotic Stenosis and Restenosis
Status: RECRUITING
Conditions: Stroke|Intracranial Atherosclerotic Stenosis
Interventions: DEVICE: DCB|DEVICE: POBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation
Status: COMPLETED
Conditions: Abdominal Pain|Post-ERCP Acute Pancreatitis
Interventions: DEVICE: Conventional 0.035 guidewire|DEVICE: Olympus Visiglide 0.025 guidewire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: AQ-13 Treatment|DRUG: Coartem Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Disitamab Vedotin (RC48) in Hormone Receptor Positive, HER2-low Metastatic Breast Cancer (the Rosy Trial)
Status: RECRUITING
Conditions: HR Positive/HER2 Low Expression Metastatic Breast Cancer
Interventions: DRUG: Disitamab vedotin|OTHER: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inpatient vs Outpatient Total Hip Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Outpatient|PROCEDURE: Inpatient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 18F-NaF-PET/MR vs 99mTc-MDP-SPECT/CT to Detect Bone Metastases in Prostate Cancer Patients.
Status: COMPLETED
Conditions: Bone Metastases|Prostate Cancer
Interventions: OTHER: scintigraphy 99mTc-MDP-SPECT/CT.|OTHER: 18F-NaF-PET/MR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Screening Program in Detecting Stenosis and Predicting Thrombosis in Hemodialysis Graft
Status: COMPLETED
Conditions: Arteriovenous Graft Stenosis|Arteriovenous Graft Thrombosis
Interventions: DIAGNOSTIC_TEST: Graft stenosis and thrombosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of R289 in Participants With Lower-risk Myelodysplastic Syndromes (LR MDS)
Status: RECRUITING
Conditions: Low Risk Myelodysplastic Syndromes
Interventions: DRUG: R906289 Monosodium (R289 Na)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Sedentary Behaviour in Adults With Type 2 Diabetes - A Randomized Controlled Trial
Status: RECRUITING
Conditions: Sedentary Behavior|Diabetes Mellitus, Type 2|Adult ALL
Interventions: BEHAVIORAL: Health Action Process Approach (HAPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of a New Ophthalmic Formulation of Bimatoprost in Patients With Open Angle Glaucoma and Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: bimatoprost 20 µg generation 2|DRUG: bimatoprost 15 µg generation 2|DRUG: bimatoprost 10 µg generation 2|DRUG: bimatoprost 6 µg generation 2|DRUG: bimatoprost 15 µg generation 1|DRUG: bimatoprost 10 µg generation 1|DRUG: bimatoprost 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cyclic DSG Compared With Cyclic MPA for the Treatment of Anovulatory DUB
Status: UNKNOWN
Conditions: Dysfunctional Uterine Bleeding
Interventions: DRUG: Desogestrel|DRUG: Medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT