pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Anti-Reflux Mucosectomy in the Treatment of Refractory Gastro-esophageal Reflux
Status: RECRUITING
Conditions: Gastroesophageal Reflux Disease With Ulceration
Interventions: PROCEDURE: endoscopic mucosal resection|PROCEDURE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Novel Use of Treadmill Plus Music in MS Patients Gate Rehabilitation
Status: UNKNOWN
Conditions: Interventional Study
Interventions: OTHER: Gait Training plus music|OTHER: Traditional Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Safety Study of Xerese Cream in the Treatment of Recurrent Herpes Labialis in Children 6-11 Years Old
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: acyclovir/hydrocortisone cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation in Patients With Early-Stage Vulvar Cancer Undergoing Sentinel Lymph Node Dissection
Status: UNKNOWN
Conditions: Stage I Vulvar Cancer|Stage II Vulvar Cancer|Stage III Vulvar Cancer|Vulvar Squamous Cell Carcinoma
Interventions: OTHER: Clinical Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Severe Impaired Renal Function
Status: UNKNOWN
Conditions: Kidney Dysfunction
Interventions: DRUG: Nemonoxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Innovational Model to Manage Patient Expectations and Improve Patient Satisfaction: An Intervention Study
Status: COMPLETED
Conditions: Patient-Centered Care|Patient Satisfaction
Interventions: OTHER: PSactive model|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Guided Online Intervention to Improve Quality of Life in Breast Cancer Patients - a Randomised Clinical Trial
Status: COMPLETED
Conditions: Cancer, Breast|Quality of Life|Distress, Emotional
Interventions: BEHAVIORAL: iACT-BC: Oncovox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Diabetes on Tramadol Pharmacokinetics
Status: COMPLETED
Conditions: Neuropathic Pain|Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: Single oral dose of 100 mg racemic tramadol|OTHER: CYP2D6 phenotype|OTHER: CYP3A phenotype|GENETIC: CYP2B6 genotype
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PBI-0451 in Healthy Subjects.
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: PBI-0451 Dose 1|DRUG: PBI-0451 Dose 2|DRUG: PBI-0451 Dose 3|DRUG: PBI-0451 Dose 4|DRUG: Ritonavir|DRUG: Midazolam|DRUG: Placebo|DRUG: PBI-0451|DRUG: PBI-0451 Dose 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Following Reduced Intensity Conditioning and Allogeneic Stem Cell Transplant for Poor Risk CD30+ Hodgkin Lymphoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|PROCEDURE: Allogeneic Stem Cell Transplantation|DRUG: Reduced Intensity Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: [O-15]-Water PET Myocardial Perfusion Imaging (MPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0002899)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal and epidermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Human Papillomavirus Infection|HPV Infection
Interventions: DEVICE: DR. Chip HPV genotyping IVD kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Vitamin D-Enriched Mushrooms on Vitamin D Status and Immune Function and Inflammatory Status in Adults
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: OTHER: Vitamin D-enriched mushrooms|OTHER: Study Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure
Status: COMPLETED
Conditions: Pediatric Heart Failure
Interventions: DRUG: LCZ696|DRUG: Enalapril|DRUG: Placebo of LCZ696|DRUG: Placebo of Enalapril|DRUG: LCZ696
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Vision Assessment and Impairment Detection Through Gaze Analysis in Wet AMD Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Age-Related Macular Degeneration|Wet Age-related Macular Degeneration
Interventions: DEVICE: Automated Vision Assessment and Impairment Detection through Gaze Analysis (AVIGA) system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dupilumab Skin BArrier Function and LIpidomics STudy in Atopic Dermatitis in China
Status: COMPLETED
Conditions: Atopic Dermatitis|Dermatitis Atopic
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICT-based Monitoring for Arrhythmia Detection After AF Ablation
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation
Interventions: DEVICE: ICT-based ECG monitoring|DEVICE: Holter monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Immune Directed Individualized Elimination Therapy (iDIET) Study
Status: ENROLLING_BY_INVITATION
Conditions: Eosinophilic Esophagitis|EoE
Interventions: DEVICE: Algorithm to diagnose food allergens|OTHER: Sham diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Bilateral Erector Spinae Plane Block in Comparison With Intrathecal Morphine After Elective Cesarean Section
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Assessments of the Postoperative Recovery on Elderly Patients Received General Anesthesia or Peripheral Nerve Blocks
Status: UNKNOWN
Conditions: Anesthesia|Hip Osteoarthritis
Interventions: PROCEDURE: Multimodal analgesic techniques|PROCEDURE: Total uni-Hip Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interval Training Plus Creatine Effects on Performance and Glucose Tolerance
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Creatine|DIETARY_SUPPLEMENT: Placebo|OTHER: High intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention and Screening Towards Elimination of Cervical Cancer
Status: COMPLETED
Conditions: HPV Infection|Cervix Cancer|Cervical Dysplasia
Interventions: BEHAVIORAL: Community mobilisation for hrHPV self-testing|DIAGNOSTIC_TEST: hrHPV self-testing|BEHAVIORAL: Follow-up after testing|DIAGNOSTIC_TEST: VIA|PROCEDURE: Thermo-ablation or cryotherapy for dysplasia|DIAGNOSTIC_TEST: Pap smear cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Acapella Versus Incentive Spirometer on Cardiopulmonary Fitness After Heart Valve Surgery.
Status: UNKNOWN
Conditions: Open Heart Surgery|Heart Valve Diseases|Heart Diseases
Interventions: DEVICE: Acapella user|DEVICE: Incentive spirometer user|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Multicenter, Open Label Study on the Effects of SNDX-275 on Expression of Biomarkers in Subjects With Newly Diagnosed Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: SNDX-275
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mobilization of Stem Cells With AMD3100 (Plerixafor) in Combination With G-CSF in Multiple Myeloma Patients
Status: COMPLETED
Conditions: Autologous Haematopoietic Stem Cell Transplant
Interventions: DRUG: plerixafor + G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting HPV Vaccination Among Young Adults in Texas
Status: RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: OTHER: Enhancing Accessibility to Health Care|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Interview|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Imaging Study in Patients With Thyroid Cancer or Head and Neck Cancer With Pertechnetate Made in a Cyclotron (C-PERT)
Status: WITHDRAWN
Conditions: Thyroid Neoplasms|Head and Neck Neoplasms
Interventions: DRUG: C-PERT|DRUG: G-PERT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of IMC-002 for the Treatment of Active Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: IMC-002 + SOC|DRUG: Placebo + SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab for Polypoidal Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Intravitreal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Visit Frequency in the Treatment of Uncomplicated Severe Acute Malnutrition: Evaluation of Operational Feasibility and Safety
Status: COMPLETED
Conditions: Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Monthly distribution of RUTF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Compreflex Wraps in Patients With Chronic Venous Insuffciency
Status: RECRUITING
Conditions: Varicose Ulcer|Venous Insufficiency of Leg
Interventions: DEVICE: Compreflex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
Status: COMPLETED
Conditions: General Anesthesia|Sevoflurane|Generic Drugs
Interventions: DRUG: original sevoflurane|DRUG: generic sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Anesthesia on Patient's Pain Discomfort and Radial Artery Spasm in Transradial Catheterization
Status: UNKNOWN
Conditions: Radial Artery Spasm
Interventions: DRUG: Topical Anesthetic|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Vasopressor Strategy in Septic Shock
Status: RECRUITING
Conditions: Shock, Septic
Interventions: OTHER: Simultaneous administration of vasopressors|OTHER: Successive administration of vasopressors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation for the Treatment of Gastric Dysplasia
Status: COMPLETED
Conditions: Gastric Dysplasia|Neoplasia
Interventions: DEVICE: Radiofrequency ablation of dysplastic mucosa (HALO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthritis of Hip
Interventions: PROCEDURE: Fascia iliaca compartment block|DRUG: Placebo|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis Related Diabetes|Pancreatic Insufficiency
Interventions: DRUG: placebo|DRUG: repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
Status: TERMINATED
Conditions: Infant,Premature|Bronchopulmonary Dysplasia|Pulmonary Hypertension
Interventions: DRUG: L-Citrulline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Keller Prehospital Ultrasound Study
Status: UNKNOWN
Conditions: Ultrasonography|Multiple Trauma|Kidney Calculi|Aortic Aneurysm, Abdominal|Pregnancy|Catheterization, Venous
Interventions: DEVICE: EFAST exam|DEVICE: Pelvic Ultrasound|PROCEDURE: Ultrasound Guided Vascular Access|DEVICE: Focused Ultrasound Scan|DEVICE: Cardiac Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Pharmacokinetics of Daclatasvir/Sofosbuvir in Adolescents With Hepatitis C Virus
Status: RECRUITING
Conditions: Chronic HCV Infection
Interventions: DRUG: Daclatasvir and sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer
Status: TERMINATED
Conditions: Stage I Oral Cavity Squamous Cell Carcinoma|Stage II Oral Cavity Squamous Cell Carcinoma
Interventions: DRUG: HPPH|OTHER: Laboratory Biomarker Analysis|DRUG: Photodynamic Therapy|OTHER: Quality-of-Life Assessment|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle/Risk Factor Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium and Immune Function
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 50ug selenium enriched yeast|DIETARY_SUPPLEMENT: 100ug selenium enriched yeast|DIETARY_SUPPLEMENT: 200ug selenium enriched yeast|DIETARY_SUPPLEMENT: Control onion|DIETARY_SUPPLEMENT: Enriched onion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Bioavailability Study of Clonazepam ODT Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Clonazepam|DRUG: Klonopin Wafers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of AirTraq Laryngoscope to Macintosh Laryngoscope for Intubation of Patients With Potential Cervical Spine Injury
Status: COMPLETED
Conditions: Trauma
Interventions: DEVICE: AirTraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Aerobic Exercise on Cancer-Related Biomarkers, Functional Capacity, Cognitive Status and Quality of Life in Women With Breast Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer Female|Quality of Life|Survivorship
Interventions: OTHER: Aerobic exercise|BEHAVIORAL: Physical activity counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-Coated Balloon Coronary Angioplasty Versus Stenting for Treatment of Disease Adjacent to a Chronic Total Occlusion.
Status: RECRUITING
Conditions: Chronic Total Occlusion of Coronary Artery
Interventions: DEVICE: Drug-Coated Balloons|DEVICE: Drug-Eluting-Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy
Status: RECRUITING
Conditions: Basal Cell Carcinoma
Interventions: DRUG: ALA|PROCEDURE: PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Test Topical AS101 for External Genital Warts
Status: COMPLETED
Conditions: Wart; External Genital Organs|Condyloma Acuminata
Interventions: DRUG: Topical AS101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norwegian Birch Rust Allergy Study
Status: COMPLETED
Conditions: Hypersensitivity, Immediate
Interventions: DIAGNOSTIC_TEST: Quationnaires and symptom registration|DIAGNOSTIC_TEST: PNIF and spirometry|DIAGNOSTIC_TEST: SPT, spesific IgE, pBAT and NPT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coping Skills Training for Symptom Management and Daily Steps (HCT Step Up)
Status: NOT_YET_RECRUITING
Conditions: Hematopoietic Stem Cell Transplant
Interventions: BEHAVIORAL: Step Up|OTHER: Usual Care Plus (UC+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety of Brimonidine/Timolol Fixed Combination in Glaucoma or Ocular Hypertension Patients
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Brimonidine 0.2%/Timolol 0.5% Fixed Combination Ophthalmic Solution|DRUG: Concurrent brimonidine 0.2% and 0.5% timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Elderly AML Patients With Induction Chemotherapy Followed by G-CSF-Mobilized Stem Cells From Haploidentical Related Donors
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Induction Chemotherapy|PROCEDURE: G-PBSC Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-assessed Internal Jugular Vein Distensibility in Advanced Chronic Heart Failure (US-IJVD in CHF)
Status: UNKNOWN
Conditions: Systolic Chronic Heart Failure|Congestion, Venous|Advanced Heart Failure
Interventions: DIAGNOSTIC_TEST: Linear ultrasound (US) assessment of the internal jugular vein
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Efficacy of Ultrasound Guided Paravertebral Block in Percutaneous Nephrolithotomy Patients
Status: COMPLETED
Conditions: Pain, Postoperative; Anesthesia, Regional
Interventions: PROCEDURE: paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Basic Life Support Cardiopulmonary Resuscitation Refresher in MS2 at St George's University
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation Skill Retention in Medical Students
Interventions: OTHER: Multimedia|OTHER: Hands-on practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Appendage Thrombosis|CVA
Interventions: DEVICE: LAmbre PlusTM Left Atrial Appendage Closure System|DRUG: Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Myomucosal Flap and Buccal Pad of Fat for the Closure of Oro-antral Fistula
Status: COMPLETED
Conditions: Oro-Antral Communication
Interventions: PROCEDURE: Double layer of buccal myomucosal Flap and buccal pad of fat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Adherence Given Individual SystemCHANGE(TM) in Advancing Nephropathy (MAGICIAN) Pilot Study
Status: COMPLETED
Conditions: Chronic Kidney Disease(CKD)
Interventions: BEHAVIORAL: SystemCHANGE (TM)|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Extracorporeal Membrane Oxygenation|Mechanical Power|Transpulmonary Mechanical Power
Interventions: PROCEDURE: Transpulmonary pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Aerobic Exercise in Patients With Primary Lower Extremity Lymphedema
Status: NOT_YET_RECRUITING
Conditions: Primary Lymphedema|Aerobic Exercise
Interventions: OTHER: Aerobic exercise on the treadmill|OTHER: Walking between 12-13 RPE (The Borg Rating of Perceived Exertion) according to the Modified Borg Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture or Self-Acupuncture in Managing Cancer-Related Fatigue in Women Who Have Received Chemotherapy for Stage I, Stage II, or Stage IIIA Breast Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Breast Cancer|Depression|Fatigue
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interleukin-12 in Treating Women With Metastatic Breast Cancer Who Have Received High-Dose Chemotherapy and Peripheral Stem Cell Transplantation
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: recombinant interleukin-12
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Advanced Auto-titrating NIV in COPD
Status: SUSPENDED
Conditions: Chronic Obstructive Pulmonary Disease Severe
Interventions: DEVICE: Auto-titrating non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Primary Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis|Polycythemia Vera
Interventions: DRUG: LNK01002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Rituximab and Combination Chemotherapy in Treating Participants With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Methotrexate|BIOLOGICAL: Rituximab|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteotomy of the 1st Metatarsal for Hallux Valgus Using Pneumatic Oscillating Saw or Piezoelectric Scalpel
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: DEVICE: Piezoelectric tool|DEVICE: Oscillating Saw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-course Radiotherapy Combined With Neoadjuvant Chemotherapy and PD-1 Inhibitor in the Treatment of Locally Advanced Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Disorder in Complete Remission in Response to Treatment
Interventions: DRUG: Sintilimal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Self-myofascial Release on Latent Trigger Point Sensitivity
Status: COMPLETED
Conditions: Trigger Points
Interventions: OTHER: Static compression of LMTRP|OTHER: Dynamic self-myofascial release of calf|DEVICE: Placebo laser acupuncture of LMTRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Clinical Outcomes and Costs of a Lifestyle Intervention in Obese Infertile Women
Status: COMPLETED
Conditions: Female Infertility|Polycystic Ovary Syndrome|Obesity
Interventions: BEHAVIORAL: Interdisciplinary lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of a Cardiovascular Risk Intervention Program in Patients With Schizophrenia (PRISCA)
Status: UNKNOWN
Conditions: Schizophrenia|Cardiovascular Risk Factor
Interventions: OTHER: Multifactorial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure.
Status: TERMINATED
Conditions: Heart Failure|Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: Allogeneic stem cells implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: flexible AIR coil|DEVICE: endorectal coi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan
Status: NOT_YET_RECRUITING
Conditions: Generalized Anxiety Disorder|Major Depressive Disorder|Social Anxiety Disorder|Somatic Symptom|Panic Attacks|Obsessive-Compulsive Disorder and Symptoms
Interventions: DEVICE: Online EMDR Therapy System|OTHER: Face to Face Eye Movement Desensitization & Reprocessing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Flumazenil for the Treatment of Primary Hypersomnia
Status: COMPLETED
Conditions: Hypersomnia|Primary Hypersomnia|Idiopathic Hypersomnia|Narcolepsy Without Cataplexy
Interventions: DRUG: Flumazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: folate|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: Placebo|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Results in Hypoplastic Aortic Arch Repair in Neonates Using a Glutaraldehyde Treated Autologous Pericardial Patch
Status: UNKNOWN
Conditions: Congenital Hypoplasia of Aortic Arch
Interventions: PROCEDURE: Aortoplasty using autologous pericardial patch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Hysterolaparoscopy in Infertile Patients With Normal Hysterosalpingography
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: PROCEDURE: Hysteroscopy|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML
Status: UNKNOWN
Conditions: High Risk Acute Myeloid Leukemia|Allogeneic Hematopoeitic Stem Cell Transplantation
Interventions: DRUG: Cladribine|DRUG: Fludarabine|DRUG: Busulfan|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tumor Factors in Breast Cancer Treated With Docetaxel and Capecitabine
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Success Rate of Prefabricated Versus Conventional Band and Loop Space Maintainers in Children With Prematurely Lost First Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Premature Tooth Exfoliation
Interventions: DEVICE: prefabricated space maintainer|DEVICE: conventional space maintainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: OTHER: Placebo|DRUG: Nipocalimab|DRUG: Standard of Care Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Dexmedetomidine on Microcirculation and Surgical Outcomes After Cardiac Surgeries
Status: COMPLETED
Conditions: Cardiac Surgical Procedure
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension
Status: COMPLETED
Conditions: Hypertension|Vitamin D Deficiency|Pre-Hypertension
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Luveris In Vitro Fertilization Trial
Status: TERMINATED
Conditions: Infertility|Hypothalamic Amenorrhea|Hyperprolactinemia
Interventions: DRUG: Luveris fixed dose|DRUG: Luveris increasing dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Stage IIIB Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Castration-Resistant Prostate Carcinoma|Prostate Adenocarcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Olaparib|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration|DRUG: Testosterone Enanthate|DRUG: Testosterone Cypionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency Study Evaluating the Use of PVAC Catheter Technology for Performing Ablation in Pts With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Radiofrequency Ablation Procedure|DEVICE: PVAC Ablation Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary & Booster Study to Evaluate the Immunogenicity and Safety of Menitorix Vaccine in Preterm Infants
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: Menitorix™|BIOLOGICAL: Infanrix™ penta|BIOLOGICAL: Prevenar™|BIOLOGICAL: Infanrix™ IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Lenalidomide With Topotecan In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: CC-5013|DRUG: topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Phase IIaTrials of GanMaoKangNing Granules
Status: UNKNOWN
Conditions: Epidemic Influenza
Interventions: DRUG: GanMaoKangNing Granules|DRUG: Analogous Oseltamivir Phosphate Capsules|DRUG: Oseltamivir Phosphate Capsules|DRUG: Analogous GanMaoKangNing Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Outcomes Between Image-based Versus Imageless Robot-assisted Unicondylar Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Arthropathy of Knee
Interventions: PROCEDURE: MAKO assisted unicondylar knee arthroplasty|PROCEDURE: NAVIO assisted unicondylar knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: Very low nicotine content cigarettes|OTHER: Standard nicotine content cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quantitative Heat Loss With Laminar Air Flow
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: standard airflow with forced air warming.|OTHER: laminar airflow with surgical drapes|OTHER: laminar airflow with forced air warming|OTHER: standard airflow with surgical drapes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MPN-RC 118 AVID200 in Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post ET MF|Post PV MF
Interventions: DRUG: AVID200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Combined Anti-PD1 Antibody for the Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Anti-PD1 Antibody|Liver Diseases
Interventions: DRUG: Lenvatinib|DRUG: Opdivo|DRUG: Camrelizumab|DRUG: Keytruda|DRUG: Toripalimab|DRUG: Sintilimab|DRUG: Tislelizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcutaneous Electrical Nerve Stimulation After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Transcutaneous Electric Nerve Stimulation|Pain
Interventions: DEVICE: Transcutaneous electrical nerve stimulation|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Paricalcitol Capsules in Pediatric Subjects Ages 10 to 16 With Stage 5 Chronic Kidney Disease Receiving Peritoneal Dialysis or Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease|Secondary Hyperparathyroidism
Interventions: DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Methodological Open Label Cross-Over Controlled Study To Assess The Effect Of Drugs On Ventricular Repolarization and QT Interval At Fixed Heart Rate Under Autonomic Blockade
Status: COMPLETED
Conditions: Patients With Pace Makers But no Evidence of Ischemic Heart Disease
Interventions: DRUG: GTN|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: ECT
Clinical trial: Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Iron-deficiency Anemia (IDA)|Pregnancy
Interventions: DRUG: daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill|DRUG: alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Together in Recovery With Veterans Through Employment
Status: RECRUITING
Conditions: Veterans With Opioid Use Disorder
Interventions: OTHER: Treatment As Usual Vocational Rehabilitation (TAU-VR)|OTHER: Individual Placement and Support (IPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of Nise 100 mg in the Management of Osteoarthrosis (Gonarthrosis)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: NISE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma, Malignant
Interventions: BIOLOGICAL: AdV-tk|DRUG: Valacyclovir|RADIATION: Radiation|DRUG: Temozolomide|BIOLOGICAL: Nivolumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in Toddlers
Status: COMPLETED
Conditions: Japanese Encephalitis|Japanese Encephalitis Virus Disease
Interventions: BIOLOGICAL: Live attenuated Japanese encephalitis chimeric virus vaccine|BIOLOGICAL: Japanese encephalitis live attenuated vaccine (SA14 14 2 vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: iPad Use in Reducing Anxiety and Depression in Patients Undergoing Bone Marrow Transplant
Status: TERMINATED
Conditions: Anxiety|Depression|Malignant Neoplasm
Interventions: OTHER: Computer-Assisted Intervention|OTHER: Computer-Assisted Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adalimumab PK Bioequivalence Study to EU and US Sourced Humira
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: BMO-2|BIOLOGICAL: EU-Humira|BIOLOGICAL: US-Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous Immunoglobulin in Combination Therapy With Antibacterial Agents for SSI of the Lower Digestive Tract
Status: WITHDRAWN
Conditions: Peritonitis|Postoperative Complications
Interventions: DRUG: intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise for the Improvement of Cognition and Enhancement of Recovery in Post-acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: endurance training|OTHER: balance and tone program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Targeted Abdominal Perfusion Pressure in Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Septicemia|Intraabdominal Hypertension|Renal Injury
Interventions: DRUG: Vasopressor Agent|DRUG: Crystalloid Solutions|PROCEDURE: Invasive Blood Pressure Monitoring|PROCEDURE: Intra-Abdominal Pressure Monitoring|OTHER: Abdominal Perfusion Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of the Individualized Metacognitive Training (EMC+) in People With Psychosis of Brief Evolution
Status: COMPLETED
Conditions: Brief Psychotic Disorder|Psychosis; Episode
Interventions: BEHAVIORAL: MCT+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury
Status: COMPLETED
Conditions: Muscle Injury|Recovery|Pain Relief
Interventions: DRUG: Active CBD|DRUG: Vehicle Control (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases|Renal Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of 12-week Custom-made Orthotic Intervention on the Structure and Function of the Foot of Healthy Young Adults During Gait Termination
Status: COMPLETED
Conditions: Flatfoot
Interventions: DEVICE: Custom-made Foot Orthotics (CFO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of (Neo)Adjuvant Therapy Associating Anthracyclines and Taxanes With or Without Trastuzumab on Skeletal Muscle in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Microbiopsy sample|OTHER: Muscle echography, Maximal strength, Body composition, Quality of life and Physical activity level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty
Status: UNKNOWN
Conditions: Puberty, Precocious|Adiposity
Interventions: OTHER: GnRHas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT