pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of PIR and MRT on Muscle Stiffness and Pain in Individuals With Bruxism
Status: ENROLLING_BY_INVITATION
Conditions: Bruxism|Post-isometric Relaxation Technique|Myofascial Release Technique
Interventions: OTHER: Post-isometric Relaxation Technique|OTHER: Myofascial Release Technique|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single Versus Repeat Doses of AM-101 in the Treatment of Acute Inner Ear Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: AM-101 0.81 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Lymphatico-venular Anastomosis and Liposuction to Treat Cancer-related Lymphedema
Status: RECRUITING
Conditions: Description of an Effective Surgical Strategy to Treat Cancer-related Lymphedema|Combination of LVA and Liposuction Guarantees Long Lasting Results
Interventions: PROCEDURE: combination of lymphaticovenular anastomosis and liposuction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: fMRI of Theory of Mind in Schizophrenia and Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder, Schizophrenia
Interventions: BEHAVIORAL: IRMf|BEHAVIORAL: Mini International Neuropsychiatric Interview|BEHAVIORAL: Positive And Negative Syndrom Scale|BEHAVIORAL: Young Mania Rating Scale|BEHAVIORAL: Hamilton Depression Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Tobacco Use Cessation|Post Traumatic Stress Disorders
Interventions: BEHAVIORAL: Motivation Interviewing Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndrome(MDS)|Acute Myelogenous Leukemia (AML)
Interventions: DRUG: Alpelisib + Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clotrimazole Enemas for Pouchitis in Children and Adults
Status: TERMINATED
Conditions: Ulcerative Colitis|Pouchitis|Ileitis|Inflammatory Bowel Disease
Interventions: DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Impaired Brain Blood Flow With Aging
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Ascorbic Acid|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Open-Label, Within-Subject Dose-Escalation Study to Evaluate the Clinical Safety and Pharmacokinetic Profile of a Topical Sildenafil Cream (5% w/w), in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Female Sexual Health
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms|Colorectal Cancer|Colorectal Cancer Metastatic|Peritoneal Metastases|Peritoneal Cancer|Peritoneal Neoplasms|Chemotherapy Effect|Cytoreductive Surgery|Hyperthermic Intraperitoneal Chemotherapy
Interventions: DRUG: Preoperative systematic therapy|PROCEDURE: CRS+HIPEC|DRUG: Postoperative chemotherapy|DRUG: Postoperative chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Furazolidone|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Boost for Oropharyngeal Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma of the Oropharynx
Interventions: RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure
Status: UNKNOWN
Conditions: Cold Exposure|Manual Dexterity|Gut Microbiome
Interventions: DIETARY_SUPPLEMENT: CocoaVia supplement|OTHER: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Aesculus Hippocastanum and Associations Versus Diosmina and Hesperidina in Chronic Venous Insuficiency
Status: RECRUITING
Conditions: Chronic Venous Insufficiency
Interventions: DRUG: Aesculus hippocastanum, and associations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WeArable Neuromodulation DeVice for the TrEatment of Alzheimer's Disease
Status: WITHDRAWN
Conditions: Mild Alzheimer's Disease
Interventions: DEVICE: Non-invasive brainstem stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction, Acute|Multi-Vessel Coronary Artery Stenosis
Interventions: PROCEDURE: Staged in-hospital or Immediate complete revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Analgesic Consumption of the Erector Spina Plane Block and Serratus Anterior Plane Block
Status: UNKNOWN
Conditions: Thoracic Diseases
Interventions: PROCEDURE: Erector Spinae Plane block ( Group ı)|PROCEDURE: Serratus Anterior Plane block ( Group ıı)|PROCEDURE: Control Group (GROUPIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of CD40.HIVRI.Env Vaccine Combined or Not With a DNA-HIV-PT123 HIV-1 Vaccine in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Adults
Interventions: BIOLOGICAL: Solo 0.3 group|BIOLOGICAL: Solo 1 group|BIOLOGICAL: Solo 3 group|BIOLOGICAL: Combi 0.3 group|BIOLOGICAL: Combi 1 group|BIOLOGICAL: Combi 3 group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a Nurse Intervention to Impact Mucositis Severity and Prevent Dehydration
Status: COMPLETED
Conditions: Lung Cancer|Mucositis Oral|Dehydration|Head and Neck Cancer
Interventions: BEHAVIORAL: Symptom Management Education and Nurse Coaching|BEHAVIORAL: Drinks Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: RO6867461
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescein Angiography With a Full-dose Versus a Half-dose of Intravenous Fluorescein
Status: SUSPENDED
Conditions: Fluorescein Angiography
Interventions: DRUG: Fluorescein Na 10% Inj 500mg|DRUG: Fluorescein Na 10% Inj 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of an Amino Acid Supplement in Adults
Status: COMPLETED
Conditions: Insulin-Like Growth Factor I|Healthy
Interventions: DRUG: Amino Acid Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Acupressure for Postoperative Nausea and Vomiting in Children Undergoing Outpatient Middle Ear Surgery
Status: COMPLETED
Conditions: Nausea|Vomiting|PONV
Interventions: OTHER: Acupressure Band|OTHER: Sham Band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Humoral Determinants of Immunity to Pneumococcal Infection
Status: COMPLETED
Conditions: Pneumonia|Pneumococcal Infections|Infections, Streptococcus Pneumoniae
Interventions: BIOLOGICAL: Prevnar|BIOLOGICAL: Pneumovax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.
Status: NOT_YET_RECRUITING
Conditions: Caries,Dental|Broken Teeth|Fracture Tooth|Defective Dentition
Interventions: PROCEDURE: onlay manufactured by milling|PROCEDURE: Onlay manufactured by 3D printing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cluster Randomised Trial of Community-led Distribution of HIV Self-tests in Rural Malawi (HIV Self-Testing Africa [STAR])
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DEVICE: OraQuick® HIV Self-Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Honey & Nigella Sativa Trial Against COVID-19
Status: COMPLETED
Conditions: Coronavirus Infection|Sars-CoV2
Interventions: DRUG: Honey|DRUG: Nigella Sativa / Black Cumin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Consequences of Crystalloids in Severely Burned Patients
Status: SUSPENDED
Conditions: Burns
Interventions: PROCEDURE: PlasmaLyte for fluid resuscitation|PROCEDURE: Ringer's Lactate for fluid resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Absorption, Metabolism and Excretion of Migalastat Hydrochloride (AT1001-014)
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: [14C] AT1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of ColcHicine on the Incidence of Knee or Hip Replacements
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BG2109 During Controlled Ovarian Hyperstimulation in Female Subjects Undergoing ART Procedures
Status: NOT_YET_RECRUITING
Conditions: Assisted Reproductive Technology|Controlled Ovarian Hyperstimulation
Interventions: DRUG: BG2109|DRUG: Cetrorelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Capecitabine With Irinotecan and Oxaliplatin (Eloxatin) in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis
Status: COMPLETED
Conditions: Head and Neck Cancers|Oral Mucositis
Interventions: OTHER: Salin|OTHER: Sodium bicarbonate|OTHER: Thyme honey|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Plastic vs. Fully Covered Self Expanding Stents (FCSEMS) for Treatment of Anastomotic Bile Leaks
Status: TERMINATED
Conditions: Bile Leak
Interventions: DEVICE: Plastic biliary stent|DEVICE: FCSEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Micronized Progesterone Effects on Perimenopausal Menstrual Flow
Status: COMPLETED
Conditions: Perimenopause|Menstrual Cramps
Interventions: DRUG: Oral Micronized Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Acupressure and Foot Exercise on Ankle Brachial Index in Individuals With Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Acupressure Group|OTHER: Sham Acupressure Group|OTHER: Foot Ankle Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Mobile Intervention to Promote Cessation in HIV-infected Smokers
Status: COMPLETED
Conditions: Tobacco Use|HIV-1-infection
Interventions: BEHAVIORAL: mobile Positively Smoke Free (mPSF)|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Efficiency Assessed by Polysomnography (PSG Sleep Lab Testing) in Advanced Parkinson's Disease
Status: TERMINATED
Conditions: Advanced Idiopathic Parkinson's Disease
Interventions: OTHER: Placebo|OTHER: Rotigotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EF5 in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: EF5|PROCEDURE: therapeutic conventional surgery|PROCEDURE: biopsy|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of Neoadjuvant Therapy With Gemcitabine and Cisplatin in Patients With Resectable or Unresectable Intrahepatic Cholangiocarcinoma
Status: TERMINATED
Conditions: Unresectable Intrahepatic Cholangiocarcinoma|Resectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|PROCEDURE: Surgery|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Anemia|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Precancerous/Nonmalignant Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: darbepoetin alfa|DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Double-Blind, Placebo-Controlled Study Assessing the Effect of Fenofibrate, Coenzyme Q10 and Their co-Administration on Ventricular Diastolic Function in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Patients With Type 2 Diabetes
Interventions: DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10|DRUG: Fenofibrate/CoQ10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography/Computed Tomography (PET/CT) in Relapsed Ovarian Cancer (MK-0000-143)
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: PROCEDURE: Comparator: 18-F-FDG PET/CT and Volumetric CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: fosamprenavir + ritonavir + methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ramelteon (TAK-375) Tablets for Sublingual Administration (SL) in Adults With Bipolar 1 Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of a Muscular Strengthening Protocol With an Instrumented Orthosis for Gonarthrosis Patients
Status: COMPLETED
Conditions: Gonarthrosis
Interventions: DEVICE: traditional rehabilitation protocol|DEVICE: with instrumented Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patients
Status: TERMINATED
Conditions: Acute Leukemia|Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Diffuse Large B-Cell Lymphoma|Follicular Lymphoma|Graft Versus Host Disease|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Myelodysplastic Syndrome|Myelofibrosis|Myeloproliferative Neoplasm|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Thymoglobulin|DRUG: Bortezomib|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Microwave Ablation in Combination With Camrelizumab Versus Camrelizumab in Metastatic Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: NSCLC Stage IV
Interventions: DRUG: Camrelizumab|OTHER: Camrelizumab plus microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open-Label Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: RVT-501 0.5% topical ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rozerem on the Perception of GERD Symptoms in Patients With Chronic Insomnia.
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease|Chronic Insomnia
Interventions: DRUG: Rozerem (ramelteon)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors
Status: COMPLETED
Conditions: Extragonadal Germ Cell Tumor|Teratoma|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: carboplatin|DRUG: cisplatin|DRUG: etoposide phosphate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myeloid-derived Suppressor Cells (MDSCs) in OSCC Patients
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Oral Cavity
Interventions: DIETARY_SUPPLEMENT: β-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery
Status: COMPLETED
Conditions: Rotator Cuff Tear|Pain, Postoperative
Interventions: DRUG: liposomal bupivicaine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Microbiota in the Systemic Immune Response
Status: COMPLETED
Conditions: Healthy|Sepsis
Interventions: DRUG: Vancomycin|DRUG: Ciprofloxacin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rehabilitative Trial for the Rescue of Neurophysiological Parameters in Progranulin Deficient Subjects
Status: COMPLETED
Conditions: Frontotemporal Dementia|GRN Related Frontotemporal Dementia
Interventions: DEVICE: Anodal transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lag-3 and Gemcitabine for Treatment of Advanced Pancreas Cancer
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine|BIOLOGICAL: LAG-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of Zone-MPC and HMS With DiAs in the Outpatient Setting
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: CGM and Insulin Pump|DEVICE: Closed-Loop Control System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Single-task, Dual-task and Analogy Training During Gait Rehabilitation
Status: UNKNOWN
Conditions: Fall|Balance|Reinvestment Propensity|Gait Rehabilitation
Interventions: BEHAVIORAL: Single-task Training|BEHAVIORAL: Dual-task Training|BEHAVIORAL: Analogy Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictors and Clinical Outcomes of Patients With Coronary Heart Disease Co-morbid Depression Post Percutaneous Coronary Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Heart Disease|Percutaneous Coronary Intervention|Depression
Interventions: PROCEDURE: percutaneous coronary intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dietary Fats on Cardiovascular Health and Insulin Sensitivity in Subjects With Abdominal Obesity
Status: COMPLETED
Conditions: Inflammation|Insulin Sensitivity
Interventions: OTHER: A 2000 kcal test meal|OTHER: A 2000 kcal test meal which accounts for 7% fat exchange with carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Intradermal Acupuncture for Acute Herpes Zoster
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: PROCEDURE: Intradermal acupuncture|PROCEDURE: Sham intradermal acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Nursing Intervention for Nurses Have Experienced Trauma: a Study Based on Swanson's Caring Theory
Status: COMPLETED
Conditions: Nurses Who Have Experienced Trauma
Interventions: OTHER: The trauma recovery nursing intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Laparoscopic Versus Hand Assisted Laparoscopic Trans-peritoneal Laparoscopic Nephrectomy as One Day Surgery (i.e.: Are There Differences in Postoperative Outcome / Convalescence)
Status: COMPLETED
Conditions: Renal Cancer
Interventions: PROCEDURE: Hand assisted laparoscopic nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability of JMKX003002 in Phase 1 Study in Healthy Subjects
Status: RECRUITING
Conditions: Safety and Tolerability
Interventions: DRUG: JMKX003002 will be administered orally|DRUG: JMKX003002 will be administered orally|DRUG: JMKX003002 will be administered orally|DRUG: Placebo in Cohorts 1 to 5|DRUG: Placebo in 2 Cohorts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myocardial Dysfunction at Early Phase of Traumatic Brain Injury : Evaluation by Two Dimensional and Speckle Tracking Transthoracic Echocardiography
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: OTHER: Transthoracic echocardiography on TBI patients|OTHER: Transthoracic echocardiography on control patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Need Of Root Canal Treatment After Coronectomy In Mandibular Third Molars
Status: COMPLETED
Conditions: Inferior Alveolar Nerve Injuries|Root Canal Treatment|Paresthesia|Third Molar|Impacted Third Molar Tooth|Coronectomy
Interventions: PROCEDURE: coronectony|PROCEDURE: root canal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Ocular Penetration of 1.5% Levofloxacin and 0.5% Moxifloxacin During Corneal Transplant Surgery
Status: TERMINATED
Conditions: Corneal Transplantation
Interventions: DRUG: 1.5% levofloxacin ophthalmic solution|DRUG: 0.5% moxifloxacin ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Controlled, Open Clinical Study on Efficacy and Safety of Acupuncture for Bladder Function Recovery After Radical Cervical Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults
Status: RECRUITING
Conditions: Alcohol Drinking|Cannabis Use
Interventions: BEHAVIORAL: Condition 1: Craving daily+PBS daily|BEHAVIORAL: Condition 2: Craving daily+PBS trigger|BEHAVIORAL: Condition 3: Craving trigger+PBS daily|BEHAVIORAL: Condition 4: Craving trigger+PBS trigger|BEHAVIORAL: Condition 5: PBS daily+ PBS trigger|BEHAVIORAL: Condition 6: Craving daily+Craving trigger|BEHAVIORAL: Condition 7: Craving daily+Craving trigger+PBS daily+PBS trigger|BEHAVIORAL: Condition 8: No daily or trigger craving or PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of SLC30A8 rs13266634 Genetic Polymorphism on Zinc Supplementation and Glycemic Control in Egyptian Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type II
Interventions: DRUG: zinc supplement plus vitamin A and E|DRUG: vitamin A and E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Salvage Therapy With Chemotherapy and Natural Killer Cells in Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma
Status: TERMINATED
Conditions: Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma
Interventions: BIOLOGICAL: Expanded haploidentical natural killer cells (NKAEs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Mouthwash Study of Pioglitazone and Simvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Pioglitazone|DRUG: Simvastatin|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 1 Study of OPB-31121 in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma(NHL)|Multiple Myeloma(MM)
Interventions: DRUG: OPB-31121
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTH Analog Type II Odontoid Fracture
Status: RECRUITING
Conditions: Odontoid Fracture
Interventions: DRUG: Abaloparatide|DEVICE: Hard collar immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Feasibility of Arthrodesis Scapula-humeral Under Arthroscopy
Status: TERMINATED
Conditions: Arthroscopy Arthrodesis Gleno-humeral
Interventions: PROCEDURE: arthroscopy arthrodesis of the shoulder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Using Idarubicin Versus Doxorubicin Chemoemulsion in Patients With Hepatocellular Carcinoma (IDADOX)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: PROCEDURE: IDA-TACE|PROCEDURE: DOX-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selective Cytopheretic Device (SCD) Trial
Status: SUSPENDED
Conditions: Acute on Chronic Systolic Congestive Heart Failure|Cardiorenal Syndrome
Interventions: DEVICE: Selective Cytopheretic Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers
Status: COMPLETED
Conditions: Implantable Defibrillator User|Terminal Illness
Interventions: BEHAVIORAL: GAME-EOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Adebrelimab Combined With Apatinib Mesylate and Chemotherapy for Neoadjuvant Therapy and Biomarker Analysis in Limited-stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small Cell Lung Cancer Limited Stage
Interventions: DRUG: Adebrelimab|DRUG: Apatinib Mesylate|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Oropharynx
Interventions: DRUG: romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain|Fibromyalgia
Interventions: DRUG: Propranolol Hydrochloride|DRUG: Placebo|BEHAVIORAL: Reactivation procedure|BEHAVIORAL: Pain neuroscience education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN)
Status: RECRUITING
Conditions: Ischemic Heart Disease|Coronary Artery Disease|Aortic Valve Stenosis|Acute Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Blood samples.|DIAGNOSTIC_TEST: Collection of right atrial appendage tissue sample.|DIAGNOSTIC_TEST: Health Survey, Clinical symptom scaling|DIAGNOSTIC_TEST: Transthoracic echocardiography (TTE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy
Status: COMPLETED
Conditions: Tendinopathy
Interventions: OTHER: Isometric exercise|OTHER: Eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Antenatal Education on Fear of Birth, Depression, Anxiety, Childbirth Self-efficacy, and Mode of Delivery in Primiparous Pregnant Women
Status: COMPLETED
Conditions: Fear of Childbirth|Antenatal Education|Depression, Anxiety|Stress|Childbirth Self Efficacy|Mode of Delivery
Interventions: BEHAVIORAL: Antenat education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors
Status: RECRUITING
Conditions: NSCLC|SCLC|CRPC|ESCC|Ovarian Carcinoma|AML|MF|Malignant Tumor
Interventions: DRUG: JAB-8263|DRUG: JAB-8263
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery
Status: COMPLETED
Conditions: Posterior Fossa Tumors
Interventions: DRUG: Bupivacaine|DRUG: morphine patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Oligoprogressive|Small-cell Lung Cancer
Interventions: DEVICE: Ablative local therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Adjuvant Therapy With Recombinant Interferon-Alpha Following Curative Resection of HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: AGS-16C3F|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With High Risk Oral Intraepithelial Neoplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Cavity Carcinoma|Oral Intraepithelial Neoplasia
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Patient Observation|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Confirmatory Study of Alemtuzumab in Japanese Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: CC-90009|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ACT-OUT Trial: ACTivity OUTcomes Based on High Carbohydrate or High Fat Diet in Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: OTHER: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Glycerin and Polysorbate 80 based artificial tear|DRUG: Formulation 1: Carboxymethylcellulose sodium, glycerin and Polysorbate 80, based artificial tear|DRUG: Formulation 2: Carboxymethylcellulose sodium, glycerin, and Polysorbate 80 based artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Comparison of Optical Coherence Tomography Guidance and Angiography-only Guidance for Percutaneous Coronary Intervention With Bioresorbable Vascular Scaffold
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Angiography-guided PCI with bioresorbable vascular scaffold|DEVICE: optical coherence tomography-guided PCI with bioresorbable vascular scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darunavir/Cobicistat vs. Lopinavir/Ritonavir in COVID-19 Pneumonia in Qatar
Status: COMPLETED
Conditions: Coronavirus|COVID|Pneumonia
Interventions: DRUG: Darunavir/Cobicistat|DRUG: Lopinavir/Ritonavir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ranibizumab Versus Dexamethasone Implant in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone intravitreal implant 0.7 mg|DRUG: Ranibizumab Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients
Status: COMPLETED
Conditions: Dental Anesthesia|Anesthesia, Local|Anesthesia, Reversal
Interventions: DRUG: OraVerse|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAC Followed by RH for the Treatment of LACC
Status: RECRUITING
Conditions: Neoadjuvant Chemotherapy|Locally Advanced Cervical Cancer|Radical Hysterectomy|Objective Response|Laparoscopy|Laparotomy|Concurrent Chemoradiotherapy|Adjuvant Therapy|Systematic Chemotherapy
Interventions: DRUG: Two cycles of neoadjuvant chemotherapy|DIAGNOSTIC_TEST: First imaging evaluation|DIAGNOSTIC_TEST: Second imaging evaluation|DRUG: The third cycles of neoadjuvant chemotherapy|PROCEDURE: RH|RADIATION: Radiochemotherapy|DIAGNOSTIC_TEST: Pathologic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Conventional vs Theta Burst rTMS
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: HFL rTMS|DEVICE: iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of LY3502970 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3502970|DRUG: [14C]-LY3502970
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hetrombopag for the Treatment of Chemotherapy-Induced Thrombocytopenia in Subjects With Malignancy.
Status: UNKNOWN
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Hetrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model
Status: UNKNOWN
Conditions: Wound Heal
Interventions: OTHER: placebo comparator|OTHER: sham comparator|OTHER: Experimental drug 1|OTHER: Experimental drug 2|DRUG: Centella asiatica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Augmenting Clozapine With Sertindole - SERCLOZ
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Serdolect|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Dead Sea Solar and Water Treatment to Sulfur Pool and Medicinal Mud Treatment in Patients With RA
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Dead Sea Solar and Water Treatment|OTHER: Sulfur Pool & Medicinal Mud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Education Provided to Family Members Caring for Colorectal Cancer Patients on Caregiving Reactions and Healthy Lifestyle Behaviors: A Prospective Quasi-experimental Study.
Status: COMPLETED
Conditions: Evaluation of the Effects of Education Provided on Family Members Caring for Colorectal Cancer Patients
Interventions: BEHAVIORAL: Educational sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Nabilone in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Agitation|Weight Loss|Pain|Oxidative Stress
Interventions: DRUG: Nabilone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Subcutaneous Secukinumab in Treatment of Subjects With Moderate to Severe Chronic Plaque-type Psoriasis as Compared to Etanercept and Placebo.
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: BIOLOGICAL: Intervention A|BIOLOGICAL: Intervention B|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma
Interventions: DRUG: Nanoliposomal CPT-11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supportive-Expressive and Emotion-Focused Treatment for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Supportive-expressive treatment|BEHAVIORAL: Emotions-Focused treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab, Tremelimumab + Radiotherapy in Gynecologic Cancer
Status: TERMINATED
Conditions: Recurrent Gynecological Cancer|Metastatic Cervical Cancer|Metastatic Ovarian Cancer|Metastatic Vaginal Cancer|Metastatic Vulvar Cancer|Metastatic Endometrial Cancer|Recurrent Cervical Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Vaginal Cancer|Recurrent Vulvar Cancer|Recurrent Endometrial Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Denosumab for Prevention and Treatment of Osteoporosis in 1st Time Liver Transplant Recipients.
Status: WITHDRAWN
Conditions: Osteoporosis
Interventions: DRUG: Denosumab Injection|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION