pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Usefulness of the Chronic Obstructive Pulmonary Disease-population (COPD-PS) Questionnaire and the COPD-6 Device in the Chronic Obstructive Pulmonary Disease Detection in a Tobacco Detoxication Consultation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Chronic obstructive pulmonary disease screening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AZD9773 Dose Escalation Study
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: AZD9773 (CytoFab)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study With IPI-926 in Patients With Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis|Fibrosis, Bone Marrow
Interventions: DRUG: IPI-926
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmentation of Atrophic Mandibule Using Poly Ether Ether Ketone Mesh
Status: UNKNOWN
Conditions: Mandible Small
Interventions: PROCEDURE: under local anasthesia,Ridge Augmention of posterior atrophic mandible by using mix of autogenous bone graft and bone substitutes is used under PEEK mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesity, Insulin Resistance, and PASC: Persistent SARS-CoV-2
Status: NOT_YET_RECRUITING
Conditions: Long COVID|Insulin Resistance|Insulin Sensitivity
Interventions: PROCEDURE: Adipose Tissue Biopsy|DIAGNOSTIC_TEST: Steady State Plasma Glucose (SSPG) Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effectiveness of Virtual Reality Relaxation Combined With Patient-Controlled Analgesia (PCA) Morphine for Those Undergoing Burn Dressing Changes
Status: UNKNOWN
Conditions: Anxiety|Pain
Interventions: DEVICE: Virtual reality relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers
Status: COMPLETED
Conditions: Advanced Solid Tumors|Head and Neck Cancer|Pancreatic Cancer|Ovarian Cancer|Renal Cell Carcinoma|Malignant Glioma|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Cabiralizumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Current Versus Russian Current Effects in Healthy Young Subjects.
Status: COMPLETED
Conditions: Healthy Young|Electric Stimulation Therapy
Interventions: DEVICE: Pulsed current|DEVICE: Russian Current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Role of Nanoemulsified Sesame Oil in Post-operative Care After Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: OTHER: application of different topical nasal solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
Status: RECRUITING
Conditions: Postmenopausal Period|Vaginal Atrophy|Vaginal Prolapse
Interventions: DEVICE: Laser Treatment|DRUG: Topical hormone estriol|DIAGNOSTIC_TEST: Сlinical blood analysis|DIAGNOSTIC_TEST: Сlinical urine test|DIAGNOSTIC_TEST: Vaginal smear|DIAGNOSTIC_TEST: Cervical oncocytology test.|DIAGNOSTIC_TEST: Extended colposcopy|DIAGNOSTIC_TEST: Pelvic ultrasound|OTHER: King's Health Questionnaire|DIAGNOSTIC_TEST: Vaginal Health Index|DIAGNOSTIC_TEST: Ultrasound investigation|DIAGNOSTIC_TEST: Perineometry|DIAGNOSTIC_TEST: Optical coherence tomography|DIAGNOSTIC_TEST: Biopsy|DIAGNOSTIC_TEST: Femoflor screen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Postoperative Girdle Following Abdominal Surgery on Pulmonary Function, Mobilisation and Postoperative Pain
Status: UNKNOWN
Conditions: Pain, Postoperative|Respiratory Depression
Interventions: PROCEDURE: No girdle|PROCEDURE: Girdle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fetal Endotracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia
Status: NOT_YET_RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Interventions: DEVICE: Fetal Endotracheal Occlusion (FETO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Inhaled Adrenalin Versus Decongestant as a Local Nasal Treatment in Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: xylometazoline HCL 0.05%|DRUG: Epinephrine 1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Drug-drug Interaction Study to Evaluate the Effects of Omeprazole 40mg on the Pharmacokinetics of SPRYCEL®
Status: COMPLETED
Conditions: Drug-drug Interaction Study
Interventions: DRUG: SPRYCEL® (dasatinib) 100 mg Film-Coated Tablets in combination with Omeprazole Delayed-Release Capsules USP, 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Robot on Physical and Psychosocial Outcomes of Persons With Dementia and Their Social Environment at Home
Status: COMPLETED
Conditions: Dementia
Interventions: DEVICE: Coach Pepper group|DEVICE: Tablet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Place of Copeptin-troponin Assay in the Elimination Diagnosis of Non-ST+ ACS
Status: RECRUITING
Conditions: Acute Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Troponin and Copeptin assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Glutathione vs. Curcumin Clinical Trial
Status: UNKNOWN
Conditions: Gulf War Syndrome
Interventions: DRUG: Curcumin|DRUG: Glutathione|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety of QAW039 in Patients With Asthma Inadequately Controlled on Standard-of-care Asthma Treatment
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: QAW039 150 mg|DRUG: QAW039 450 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Status: COMPLETED
Conditions: Oral Findings in Children of Multiple and Single Births|Radiographic Evaluation of Oral Findings in Children of Multiple and Single Births
Interventions: OTHER: The contribution of genetics to dental caries, oral habits and occlusal traits in children of multiple births
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: " Application of Art Therapy in Oncology: Evaluation of the Symptomatic of Patients Suffering From a Cancerous Disease"
Status: UNKNOWN
Conditions: Therapy-Associated Cancer
Interventions: BEHAVIORAL: Art therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acupuncture for Chronic Pelvic Pain
Status: RECRUITING
Conditions: Acupuncture, Chronic Pelvic Pain, Woman
Interventions: DEVICE: Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Colo-rectal Cancer|Neuropathy;Peripheral|Mucositis
Interventions: DRUG: Pentoxifylline|DRUG: Placebo|DRUG: FOLFOX-6 regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Effects of Selective I(f)-Channel Blockade
Status: UNKNOWN
Conditions: Postural Orthostatic Tachycardia Syndrome
Interventions: DRUG: beta-blocker (Metoprolol)|DRUG: I(f)-blocker (ivabradine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine
Status: ACTIVE_NOT_RECRUITING
Conditions: Thoracic Cancer|Spine Cancer|Thoracic Diseases|Spine Disease|Thoracic Neoplasms|Spine Metastases
Interventions: DIAGNOSTIC_TEST: MRI with custom MRI spine coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Long-term Safety of QVA149
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QVA149|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hair Stimulating Complex (HSC) on Hair Growth in Males With Androgenetic Alopecia
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: BIOLOGICAL: Hair Stimulating Complex (HSC)|DEVICE: Dulbecco's Modified Eagle Medium, DMEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breathing Effort in Covid-19 Pneumonia: Effects of Positive Pressure, Inspired Oxygen Fraction and Decubitus
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DEVICE: Esophageal catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aurora: A Human-centered Program for Breast Cancer Patients in Chile, Easing Neoadjuvant Chemotherapy's Effects
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Experimental Aurora Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Written Versus Verbal Brief Cognitive Behavioral Exposure Therapy
Status: COMPLETED
Conditions: Written Exposure Therapy|Imaginal Exposure Therapy
Interventions: BEHAVIORAL: Written Exposure Therapy|BEHAVIORAL: Imaginal Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A-priori Versus Provisional Heparin on Radial Artery Occlusion After Transradial Coronary Angiography and Patent Hemostasis
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Patent hemostasis and heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CyberKnife Radiosurgery For Low & Intermediate Risk Prostate Cancer: Emulating HDR Brachytherapy Dosimetry
Status: COMPLETED
Conditions: Prostate Cancer|Prostatic Cancer|Prostatic Neoplasms|Prostate Neoplasms|Cancer of the Prostate
Interventions: RADIATION: CyberKnife Stereotactic Radiosurgery - Low Risk|RADIATION: CyberKnife Stereotactic Radiosurgery - Intermediate Risk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Variables in Cataract Surgery
Status: COMPLETED
Conditions: Cataract Surgery
Interventions: DRUG: Gatifloxacin|DRUG: Ketorolac LS|DRUG: Pred Forte|DRUG: Moxifloxacin|DRUG: Nepafenac|DRUG: EconoPred Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: A Study to Determine the Efficacy and Safety of Two Mometasone Dry Powder Inhalers in the Treatment of Asthma (Study P02524)
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: MF|DEVICE: MF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Collagen Versus PRF on BMA Osteogenic Potential
Status: RECRUITING
Conditions: Bone Loss, Alveolar
Interventions: PROCEDURE: Collagen membrane over BMAC/bovine graft in sinus lift|PROCEDURE: PRF membrane over BMAC/bovine graft in sinus lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Status: WITHDRAWN
Conditions: Perinatal Death|Respiratory Distress Syndrome, Newborn|Hypoxic-Ischemic Encephalopathy|Neonatal Seizure|Meconium Aspiration Syndrome|Intracranial Hemorrhages|Neonatal Hypotension
Interventions: OTHER: Room air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Investigational Drug Versus Placebo in the Treatment of Cancer Pain (0663-083)
Status: WITHDRAWN
Conditions: Bone Neoplasms
Interventions: DRUG: MK0663, etoricoxib / Duration of Treatment: 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fentanyl Versus Midazolam As Additives To Bupivacaine In Ultrasound Guided Transversus Abdominis Plane Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ultrasound Guided Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes (UH3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Behavior|Hiv
Interventions: BEHAVIORAL: Data-informed Stepped Care (DiSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity Study of Two Doses of an Inactivated H5N1 Influenza Vaccine (Whole Virion, Vero Cell Derived)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Whole virion, Vero cell-derived influenza vaccine containing either 3.75 µg or 7.5 µg H5N1 hemagglutinin (HA) antigen in a non-adjuvanted formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multi-center Retrospective Study With Secondary Use of Data of Tafinlar (Dabrafenib) Plus Mekinist (Trametinib) in Chinese Patients With BRAF V600 Mutation Positive Melanoma
Status: COMPLETED
Conditions: BRAF V600 Mutation Positive Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Auto-Adjustable MOBIDERm Autofit Armsleeve in the Management of Upper Limb Lymphedema.
Status: NOT_YET_RECRUITING
Conditions: Lymphedema of Upper Limb
Interventions: DEVICE: MOBIDERM Autofit Armsleeve|DEVICE: Compressive bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Pulmozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of NUV-422 in Combination With Enzalutamide in Patients With mCRPC
Status: WITHDRAWN
Conditions: Prostate Cancer|Prostatic Cancer|Cancer of Prostate|Cancer of the Prostate|Prostate Neoplasm|Castrate Resistant Prostate Cancer|Castration Resistant Prostatic Cancer|Castration Resistant Prostatic Neoplasms
Interventions: DRUG: NUV-422|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Value of a Dosage of Anti-cetuximab in the Therapeutic Management of Patients With Colon Cancer or Upper Aero-digestive Tract and Candidates for Treatment With Cetuximab
Status: COMPLETED
Conditions: Colon Cancer|Head and Neck Cancer|Allergic Reaction
Interventions: OTHER: blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Validate Questionnaires FLARE and OM-RA-FLARE Measuring Disease Flares in Patients With Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Gemcitabine With Abraxane and Other Investigational Therapies in Neoadjuvant Treatment of Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Chemotherapy|DRUG: Chemotherapy + ChemoRadiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease
Status: UNKNOWN
Conditions: Ischemic Heart Disease
Interventions: RADIATION: Cardiac MRI, Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib and Docetaxel in Second Line of Treatment in Patients With Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Erlotinib + docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Local Hemostatic in Patients With Large Incisional Hernias
Status: COMPLETED
Conditions: Hernia, Ventral
Interventions: PROCEDURE: Incisional hernia repair by the mesh implant in sublay retromusuclar position|PROCEDURE: Incisional hernia repair by the mesh implant in sublay retromusuclar position with using a local hemostatic Hemoblock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Self-retaining Bicanalicular Intubation Stent Versus Bicanalicular Silicone Tube for Management of Canalicular Obstruction
Status: UNKNOWN
Conditions: Canalicular Obstruction
Interventions: DEVICE: Self-retaining bicanalicular intubation stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Soft Robotics Approach Towards Finger Joint Deformities in Rheumatic Diseases
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Control Group|DEVICE: Soft Robotic Glove Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616; Org 25969) in Elderly Participants With Adult Participants (MK-8616-029)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex|DRUG: Rocurium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of SB-683699 Compared To Placebo In Subjects With Relapsing-Remitting Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Placebo|DRUG: Firategrast 150 mg|DRUG: Firategrast 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD Treatment for Veterans With Serious Mental Illness to Improve Functional Outcomes
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic; Mental Disorders
Interventions: BEHAVIORAL: Written Exposure Therapy|BEHAVIORAL: PTSD Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPB-51602 in Locally Advanced Nasopharyngeal Carcinoma Prior to Definitive Chemoradiotherapy
Status: TERMINATED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: OPB-51602
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changing the Paradigm of In-Hospital Cardiopulmonary Resuscitation With Informed Assent
Status: COMPLETED
Conditions: Oxygen Dependent COPD|Advanced Malignancy
Interventions: BEHAVIORAL: Informed Assent|BEHAVIORAL: Informational Brochure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS
Status: RECRUITING
Conditions: Acute Myeloid Leukemia Refractory|Myelodysplastic Syndrome Acute Myeloid Leukemia|Myelodysplastic Syndrome With Excess Blasts|Acute Myeloid Leukemia, in Relapse
Interventions: DRUG: APL-4098|DRUG: Azacitidine and APL-4098
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Inhaled XW001 For Hospitalized COVID-19 Patients Requiring Oxygen Therapy
Status: WITHDRAWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: XW001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Combining Peri-hamstring Injection or Anterior Obturator Nerve Block on the Analgesic Efficacy of Adductor Canal Block for Arthroscopic Anterior Cruciate Ligament Reconstruction Under General Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Adductor Canal Block
Interventions: PROCEDURE: adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sedation and Psychopharmacology in Critical Care
Status: TERMINATED
Conditions: Sedation|Mechanical Ventilation|Depression|Post-traumatic Stress Disorder|Quality of Life
Interventions: PROCEDURE: Daily interruption of sedation versus sedation algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Effectiveness of Electroconvulsive Therapy in Severe Depression
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: ECT Mecta 5000M|DRUG: Methohexitone|DRUG: Suxamethonium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)
Status: RECRUITING
Conditions: Ovary Cancer|Endometrial Cancer|Uterine Cancer|Cervical Cancer|Cervix Cancer|Vulvar Cancer|Vaginal Cancer
Interventions: BEHAVIORAL: Fit4Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Four-Drug Combination Therapy With Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Traditional Method and Eras Protocol in Obesity Surgery
Status: COMPLETED
Conditions: Obesity, Morbid|Bariatric Surgery Candidate|Obesity Adult Onset|Obesity Associated Disorder|Diabetes|Nausea|Ache|Pain, Postoperative|Postoperative Nausea|Postoperative Nausea and Vomiting|Post Procedural Discharge|ERAS|DVT
Interventions: PROCEDURE: Surgical Procedure with ERAS Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CHAIROS Study A Study of MabThera/Rituxan (Rituximab) Maintenance Therapy in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Naive to Chemotherapy
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: fludarabine|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mechanical Insufflation-Exsufflation With Optimized Settings on Wet Mucus Volume During Invasive Ventilation
Status: NOT_YET_RECRUITING
Conditions: Mucus Retention|Mechanical Ventilation Complication
Interventions: DEVICE: MI-E Intervention protocol|DEVICE: Standard MI-E setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation of the Motor Cortex in Essential Tremor
Status: UNKNOWN
Conditions: Essential Tremor|Transcranial Direct Current Stimulation
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Stenosis
Interventions: DRUG: Captopril and Trandolapril|DRUG: Captopril Test Dose and Trandolapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral and Neural Characteristics of Adaptive Speech Motor Control
Status: RECRUITING
Conditions: Speech
Interventions: BEHAVIORAL: Auditory feedback perturbation during speech|BEHAVIORAL: Visual feedback perturbation during reaching|OTHER: DBS stimulation ON/OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis|NASH
Interventions: DRUG: ALN-HSD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: contingency management for smoking abstinence|DRUG: transdermal nicotine|BEHAVIORAL: Telephone counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 30 Week Study of the Combination of ABT-335 and Rosuvastatin Compared to Rosuvastatin Monotherapy for Subjects With Dyslipidemia and Stage 3 Chronic Kidney Disease
Status: COMPLETED
Conditions: Dyslipidemia|Kidney Disease
Interventions: DRUG: ABT-335 plus rosuvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease: Optimal Pulse Pressure Regime
Status: COMPLETED
Conditions: Peripheral Artery Disease|Intermittent Claudication|Lower Extremity Claudication
Interventions: DEVICE: Intermittent negative pressure device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Human Cytomegalovirus (HCMV) Hyperimmune Globulin to Prevent Congenital HCMV Infection
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: DRUG: HCMV-specific hyperimmune globulin (Cytotect®)|DRUG: Isotonic solution of sodium chloride (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safeguarding the Brain of Our Smallest Children-IIIv (SafeBoosC-IIIv)
Status: NOT_YET_RECRUITING
Conditions: Hypoxia|Infant, Newborn, Diseases
Interventions: DEVICE: Cerebral oximetry monitoring device|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deferasirox BID (Twice a Day) in Transfusion Dependent Thalassemia Patients With Inadequate Response to High Doses
Status: WITHDRAWN
Conditions: Focus on Transfusion Dependent Thalassemia Patients Who Are Inadequate Responders to Deferasirox > 35mg/kgQD
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: ReCell and Split-thickness skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging Study
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: TD-1473|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarker Study of Blood Samples From Patients With Non-Small Cell Lung Cancer Treated With Carboplatin and Paclitaxel With or Without Bevacizumab
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel|GENETIC: proteomic profiling|OTHER: laboratory biomarker analysis|OTHER: matrix-assisted laser desorption/ionization time of flight mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Proliferative Diabetic Retinopathy
Interventions: BIOLOGICAL: Brolucizumab 6 mg|PROCEDURE: Panretinal photocoagulation laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure
Status: RECRUITING
Conditions: HCC
Interventions: DRUG: Nimotuzumab|DRUG: ICIs(Immune checkpoint inhibitors)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-FAPI-RGD PET/CT for Dual Integrin αvβ3 and FAP-targeted Imaging in Patients With Various Types of Cancer and Compared With 18F-FDG
Status: COMPLETED
Conditions: Tumor, Solid|Positron-Emission Tomography
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET/CT, 68Ga-FAPI-RGD PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
Status: NOT_YET_RECRUITING
Conditions: HIV-1-infection|Frailty|Impaired Physical Function|Abdominal Obesity|Aging
Interventions: DRUG: Tesamorelin|DRUG: Placebo|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Different Formulations of an Intramuscular A/H5N1 Inactivated, Split Virion Influenza Adjuvanted Vaccine
Status: COMPLETED
Conditions: Influenza|Orthomyxoviridae Infections
Interventions: BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Monovalent subvirion H5N1 influenza vaccine|BIOLOGICAL: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Serratus Anterior Plane Block on Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
Interventions: DRUG: Ropivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed Diffuse Large B-cell Lymphoma|Refractory Diffuse Large B-cell Lymphoma
Interventions: DRUG: DPX-Survivac|DRUG: Pembrolizumab|DRUG: CPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromagnetic Field Effects of Mobile Communication (LTE) on Sleep in the Context of Genetic Variation
Status: COMPLETED
Conditions: Sleep
Interventions: OTHER: LTE field|OTHER: sham field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Substance Abuse Treatment to HIV Care II (SAT2HIV-II) Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use
Interventions: BEHAVIORAL: The facilitation, training, feedback, and consultation (FTFC) Strategy|BEHAVIORAL: The facilitation, training, feedback, consultation, and pay-for-performance (FTFC+PFP) Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Is Reduced Hypoxia Through a Robot Intervention, Associated With Sensory and Emotional Descriptions of Dyspnea, Anxiety, Depression, Symptom Burden and Anxiolytics
Status: COMPLETED
Conditions: COPD|Dyspnea|Anxiety|Depressive Symptoms|Hypoxia|Closed-Loop Communication
Interventions: DEVICE: O2matic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma
Status: COMPLETED
Conditions: Intraocular Retinoblastoma
Interventions: DRUG: Carboplatin|PROCEDURE: Cryosurgery|PROCEDURE: Infrared Laser Therapy|RADIATION: Iodine I-125|RADIATION: Radiation Therapy|RADIATION: Ruthenium Ru-106|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Plus Chemoradiation in Patients With Potentially Resectable Gastric Carcinoma
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: RADIATION: S1，oxaliplatin，radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Combined With PD-L1 Plus Regorafenib in the Treatment of Advanced Hepatocellular Carcinoma After Immunotherapy Failure
Status: NOT_YET_RECRUITING
Conditions: HCC - Hepatocellular Carcinoma
Interventions: DRUG: PD-L1 inhibitor: Adebrelimab Injection；Regorafenib Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)
Status: COMPLETED
Conditions: Weight Loss|Diabetes Mellitus, Type 2|Psychotic Disorders
Interventions: BEHAVIORAL: Premier Lifestyle Intervention with DASH Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dynamic Knee Stability and Functional Outcomes in Anatomical ACL Reconstruction at AM or Central Position
Status: UNKNOWN
Conditions: Rupture of Anterior Cruciate Ligament|Complete Tear, Knee, Anterior Cruciate Ligament
Interventions: PROCEDURE: Anatomical ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: Placebo|DRUG: KVD900 600 mg|DRUG: KVD900 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROSPECTIVE ANALYSIS BETWEEN AMIODARONE Versus LIDOCAINE IN SVT
Status: UNKNOWN
Conditions: Arrhythmias Ventricular
Interventions: DRUG: Antiarrythmic Drugs|DRUG: Antiarrhythmic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Androgen Deprivation With Leuprolide, +/- Docetaxel for Clinically Asymptomatic Prostate Cancer Participants With a Rising Prostate Specific Antigen (PSA)
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Leuprolide|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dome-type (Modified C-incision) Manual Morcellation During Laparoscopic Uterine Surgery
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified
Interventions: PROCEDURE: Dome-type (Modified C-incision) manual morcellation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ABT-888 in Combination With Temozolomide in Cancer Patients
Status: COMPLETED
Conditions: Non-hematologic Malignancies|Metastatic Melanoma|Breast Cancer|Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer|Hepatocellular Carcinoma
Interventions: DRUG: ABT-888|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PREVAIL Study
Status: COMPLETED
Conditions: In-stent Restenosis|Ischemic Heart Disease|Coronary Artery Disease
Interventions: DEVICE: Medtronic Coronary Drug-Coated Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Intellectual, Psychological and Behavioural Developments Between 6 and 9 Years of the Children Born to Hyperthyroid Mothers During Their Pregnancy
Status: UNKNOWN
Conditions: Hyperthyroid
Interventions: BEHAVIORAL: Assessment of intellectual development, capacities of attention, learning process and degree of hyperactivity of the children between 6 and 9 years.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Immunosuppressive Therapy Combined With Cord Blood Transfusion in Treatment of Severe Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Thymoglobulin|PROCEDURE: Cord blood|DRUG: Cyclosporine Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Treximet, Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: sumatriptan succinate/naproxen sodium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open Investigation Evaluating the Efficacy of Nobel Biocare SFB and CFB Implants
Status: COMPLETED
Conditions: Partial Edentulism|Complete Edentulism
Interventions: DEVICE: NobelActive Internal implant|DEVICE: NobelActive External implant|DEVICE: NobelReplace Tapered Groovy implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
Status: RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: Thyrogen|RADIATION: I-131|RADIATION: I-124|OTHER: Thyroid hormone withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Post-traumatic Osteoarthritis
Interventions: PROCEDURE: Unicompartmental Biologic Arthroplasty|PROCEDURE: Extensive Biologic Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Postpartum Pain Management Protocol Comparison
Status: COMPLETED
Conditions: Pain|Post Partum Depression|Opioid Use|Breast Feeding
Interventions: DRUG: Paracetamol 1000 Mg Oral Tablet|DRUG: Ibuprofen 400Mg Tab|DRUG: Paracetamol 1000 Mg Oral Tablet|DRUG: Ibuprofen 400 mg|DRUG: MIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of NovoSeven® and a NovoSeven® Formulation Stable at Room Temperature in Healthy Male Subjects
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Acquired Haemophilia|Congenital Bleeding Disorder|Congenital FVII Deficiency|Glanzmann's Disease|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors|Healthy
Interventions: DRUG: activated recombinant human factor VII|DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib (Tarceva) in Participants With Resected Head and Neck Squamous Cell Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: Erlotinib|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Clinical Research on Single Roux-en-Y and Traditional Roux-en-Y of Pancreaticojejunostomy-choledochojejunostomy For Treatment of Obstruction of Pancreatic Duct and Bile Duct
Status: UNKNOWN
Conditions: Pancreatic Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR)
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DIETARY_SUPPLEMENT: Lactobacillus salivarius PS7 during 6 months|DIETARY_SUPPLEMENT: Lactobacillus salivarius PS7 during 3 months|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Midodrine and Albumin in Patients With Refractory Ascites
Status: UNKNOWN
Conditions: Refractory Ascites
Interventions: DRUG: Albumin|DRUG: Midodrine|DRUG: Standard medical therapy (SMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT