pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Treating Depression in Patients With De Quervain's Tenosynovitis; An Integrated Web Based Skills Intervention
Status: TERMINATED
Conditions: De Quervain Disease
Interventions: OTHER: Decision Aid|BEHAVIORAL: Toolkit for de Quervain's
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Ethanol Lock Therapy Study.
Status: COMPLETED
Conditions: Catheter-Related Infections
Interventions: DRUG: 25% ethanol|OTHER: heparin lock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Immunogenicity and Efficacy of GlaxoSmithKline (GSK) Biologicals' Candidate Malaria Vaccine RTS,S/AS02A, When Administered to Children Aged 1 to 4 Years Living in a Malaria-endemic Region of Mozambique.
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: RTS,S/AS02A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Low dose oxelidine group|DRUG: High dose oxelidine group|DRUG: Hydromorphone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence to Exercises for Neck Pain.
Status: RECRUITING
Conditions: Treatment Adherence and Compliance
Interventions: OTHER: Education|DEVICE: Chatbot|OTHER: Home exercise, usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carbetocin Versus Misoprostol in Cases With Placenta Previa After C.S.
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adebelizumab Combined With Chemotherapy and Radiotherapy Treat ES-SCLC
Status: RECRUITING
Conditions: Extensive Small Cell Lung Cancer
Interventions: DRUG: Adebelizumab+Carboplatin+Etoposide+Concurrent Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Interventions for Developmental Dyslexia
Status: UNKNOWN
Conditions: Developmental Dyslexia
Interventions: BEHAVIORAL: Rhythmic Reading Training|BEHAVIORAL: Visual Hemispheric-Specific Stimulation + Action Video Games|BEHAVIORAL: Action Video Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Moxidectin in Adults With Scabies
Status: RECRUITING
Conditions: Scabies
Interventions: DRUG: Moxidectin Oral Product|DRUG: Moxidectin Oral Product|DRUG: Moxidectin Oral Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence-supported Reading Versus Standard Double Reading for the Interpretation of Magnetic Resonance Imaging in the Detection of Local Recurrence for Nasopharyngeal Carcinoma: a Randomised Controlled Multicenter Study
Status: NOT_YET_RECRUITING
Conditions: Artificial Intelligence Supported Image Reviewing
Interventions: DIAGNOSTIC_TEST: AI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients After Switching to Tiotropium Plus Olodaterol Fixed Dose Combination in Greece
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium bromide plus Olodaterol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Volumetric Hemodynamic Parameters and Nutritional Status in Stable Renal Transplant Recipients
Status: COMPLETED
Conditions: Cardiac Output, Low|High Blood Pressure
Interventions: DEVICE: CardioScreen 1000|DEVICE: Tanita 418- Bioelectrical impedance analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Thyroidectomy Versus Open Thyroidectomy for Papillary Thyroid Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Thyroid Cancer
Interventions: PROCEDURE: Endoscopic surgery;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Restylane-Defyne for Punctual Occlusion
Status: COMPLETED
Conditions: Mild to Moderate Dry Eye Disease
Interventions: DEVICE: Restylane Defyne
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Articaine Efficiency in Pulpectomy of Children With Irreversible Pulpitis Under the Age of Four
Status: RECRUITING
Conditions: Dental Pulp Diseases
Interventions: DRUG: articaine hydrochloride 4% with epinephrine 1:100 000|DRUG: Lidocaine hydrochloride 2% with epinephrine 1:100 000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Aerosol L9-NC and Temozolomide in Ewing's Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma
Interventions: DRUG: Temozolomide|DRUG: L9-NC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Sleep Apnea and Sympathetic Activity in Resistant Hypertensive Patients.
Status: COMPLETED
Conditions: Type 2 Diabetes|Diabetic Nephropathy|Hypertension|Sleep Apnea
Interventions: DEVICE: NCPAP; Nasal continuous positive airway pressure.|DEVICE: NCPAP Nasal Continuous Positive Airway Pressure-sub-therapeutic treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sorafenib and Infusional 5-Fluorouracil in Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Infusional 5-Fluorouracil|DRUG: Sorafenib (Bay 43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients
Status: COMPLETED
Conditions: Essential Tremor|Deep Brain Stimulation
Interventions: OTHER: Alternating stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Adult Acute Basophilic Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Active Nutritional Support On Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy
Status: RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: DIETARY_SUPPLEMENT: various available nutrition as those contain high protein content as ensure milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Computer-Assisted Tailored Cue-card Health [CATCH] Study
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|STDs|Hepatitis, Viral, Human
Interventions: BEHAVIORAL: Tailored Cue Cards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Goal Management Training for Parkinson Disease Mild Cognitive Impairment
Status: COMPLETED
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Goal Management Training|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Extracorporeal Shockwave Therapy for Erectile Dysfunction in Radically Prostatectomised Men.
Status: UNKNOWN
Conditions: Erectile Dysfunction|Extracorporeal Shockwave Therapy|Radical Prostatectomy
Interventions: DEVICE: Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Does Rehabilitation After Total Hip Or Knee Arthroplasty Work (DRAW2)
Status: UNKNOWN
Conditions: Rehabilitation|Telerehabilitation|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: Homebased telerehabilitation|PROCEDURE: Homebased rehabilitation|PROCEDURE: No physical rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B|HBV
Interventions: DRUG: Single Ascending Dose (SAD) Cohorts GS-9620|DRUG: Multiple Ascending Dose (MAD) Cohorts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conbercept in Choroidal Neovascularization Secondary to Uveitis
Status: UNKNOWN
Conditions: Choroidal Neovascularization|Uveitis
Interventions: DRUG: Conbercept|DRUG: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality Treadmill Training in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Fall
Interventions: DEVICE: C-Mill augmented reality treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Total-Body Irradiation Followed by Donor Umbilical Cord Blood Transplant, Cyclosporine, and Mycophenolate Mofetil in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: graft-versus-tumor induction therapy|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Post Coronary Bypass Surgery
Status: COMPLETED
Conditions: Post Coronary Bypass Surgery Patients
Interventions: DRUG: Rivaroxaban and aspirin 80|DRUG: Aspirin 80
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study With GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GLPG0634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis
Status: WITHDRAWN
Conditions: Sporadic Inclusion Body Myositis
Interventions: DRUG: REGN2477+REGN1033|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADVATE 2 mL Post-Authorization Safety Surveillance (PASS)
Status: COMPLETED
Conditions: Hemophilia A|Congenital Factor VIII (FVIII) Deficiency
Interventions: BIOLOGICAL: Octocog alfa (recombinant human coagulation factor VIII) [ADVATE]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ixazomib Plus Lenalidomide and Dexamethasone in Adult Japanese Participants With Relapsed and/or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Immunoglobulin in Patients With PID Requiring IgG Replacement Therapy
Status: COMPLETED
Conditions: Primary Immune Deficiency
Interventions: BIOLOGICAL: Human Normal Immunoglobulin for Subcutaneous Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Immunization of HIV-1 Infected, Pregnant Women With CD4 Lymphocyte Counts >= 400/mm3: A Phase I Study of Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine (NOTE: Some Patients Receive Placebo)
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Comparison Of Erector Spinae Plane Block With Transversus Abdominis Plane Block For Postoperative Pain Management In Patients Undergoing Total Abdominal Hysterectomy
Status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Erector Spinae Plane Block(Bilateral Ultrasound Guided Erector Spinae Plane Block)|PROCEDURE: Transversus abdominis plane block(Bilateral Ultrasound-guided bilateral Transversus abdominis plane block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Psychoeducation Program in Patients With Severe Mental Disorder
Status: COMPLETED
Conditions: Mental Health Disorder|Healthy Lifestyle
Interventions: BEHAVIORAL: Psychoeducation program|DRUG: Psychopharmacology intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of White Noise and Kangaroo Care Practices on Stress Parameters in Newborns With Heel Lancing
Status: COMPLETED
Conditions: Healthy Newborns
Interventions: OTHER: Kangaroo care and White noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efprezimod Alfa (CD24Fc, MK-7110) Administration to Decrease Low-Density Lipoprotein (LDL) and Inflammation in Human Immunodeficiency Virus (HIV) Patients (CALIBER) (MK-7110-003)
Status: TERMINATED
Conditions: HIV Infections|Dyslipidemias
Interventions: DRUG: Efprezimod alfa (human CD24 extracellular domain and human IgG1 Fc fusion protein)|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Conventionally-fractionated WPRT|RADIATION: Hypofractionated WPRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder Overactive|Urinary Bladder Diseases\Urologic Diseases|Overactive Bladder|Urgency Incontinence
Interventions: DRUG: Solifenacin succinate|DRUG: Mirabegron|DRUG: Placebo to match solifenacin succinate|DRUG: Placebo to match mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics And Safety Study Of Elelyso(tm) In Pediatric Subjects With Type 1 Gaucher Disease
Status: WITHDRAWN
Conditions: Type 1 Gaucher Disease
Interventions: DRUG: Elelyso 60 units/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Astrocytoma, Grade IV
Interventions: BIOLOGICAL: Allogeneic cytomegalovirus-specific T cells|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytarabine and Clofarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: clofarabine|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Status: UNKNOWN
Conditions: Infertility and at High Risk of OHSS
Interventions: DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study to Evaluate the Safety and Efficacy of PH100 Tablet in T2DM Patients With Recent Cardiovascular
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Circulatory Complciation
Interventions: DRUG: Ecklonia cava Phlorotannin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A New Paradigm for Illness Monitoring and Relapse Prevention in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Device: Smartphone|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prebiotic Fibres on Weight Loss in an Overweight and Obese Population
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Fiber-containing dietary supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.
Status: RECRUITING
Conditions: Malignant Solid Tumor
Interventions: DRUG: HDM201|DRUG: Ribociclib|DRUG: Cabozantinib|DRUG: Alectinib|DRUG: Regorafenib|DRUG: Trametinib|DRUG: Dabrafenib|DRUG: Avapritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Biopsy in Early Breast Cancer: a Real-world Multicenter Cross-sectional Study (CABS001 Study)
Status: UNKNOWN
Conditions: Breast Cancer|Sentinel Lymph Node
Interventions: DIAGNOSTIC_TEST: mapping agent|PROCEDURE: neoadjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Suturing Distance From the Wound Edge, 2 mm vs 5 mm
Status: COMPLETED
Conditions: Cutaneous Sutures and Scar Cosmesis
Interventions: DEVICE: Fast absorbing gut suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Conventional 3D Radiation vs. Intensity-Modulated Radiation in Squamous Cell Cancer of the Head and Neck
Status: WITHDRAWN
Conditions: Head and Neck Neoplasms|Squamous Cell Cancer
Interventions: PROCEDURE: Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Parametrial Lymph Nodes as Sentinel Nodes in Patients With Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: PROCEDURE: Single Photon Emission Computed Tomography|PROCEDURE: Intraoperative Lymphatic Mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients Who Have Failed First Line Treatment for Locally Advanced and/or Metastatic Cervical Cancer
Status: TERMINATED
Conditions: Uterine Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: 5-FluoroUracil|DRUG: Folinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Psychomotor Stimulation in the Physical and Cognitive Function in the Functional Capacity of Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Cognitive and psychomotor stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ToleroMune House Dust Mite (HDM) Tolerability Study
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: BIOLOGICAL: ToleroMune HDM|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Oral N-Acetyl Cysteine Versus Rectal Diclofenac in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis
Status: RECRUITING
Conditions: Post ERCP Pancreatitis
Interventions: DRUG: Rectal Diclofenac|DRUG: Oral N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Diabetes Telemedicine Consultation: A Systems Improvement Intervention
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Diabetes Mellitus, Type 1|Primary Care Provider
Interventions: BEHAVIORAL: The Diabetes Treatment Satisfaction Questionnaire|BEHAVIORAL: Diabetes Empowerment Scale|BEHAVIORAL: CBOC's undergo half-day joint-clinics via teleconference
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Status: COMPLETED
Conditions: Myalgic Encephalomyelitis|Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: GutMagnific™ H.|DIETARY_SUPPLEMENT: GutMagnific™ L.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Squamous Cell Carcinoma of the Esophagus
Interventions: DRUG: Monalizumab|DRUG: Oxaliplatin|DRUG: 5-Fluorouracil|RADIATION: Metabolic|OTHER: Metabolic|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic GVHD
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
Status: RECRUITING
Conditions: ARDS, Human|Lung Injury, Acute|Respiratory Distress Syndrome|Mechanical Ventilation Complication|Alveolar Edema|Right Heart Failure|Right Ventricular Dysfunction
Interventions: PROCEDURE: PEEP ARDSnet|PROCEDURE: PEEP LRM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Glycaemic Variability in Frail or Disabled Older Patients With Diabetes Over 75 Treated With Basal Insulin
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness of Cervical Stabilization Exercises in Individuals With Temporomandibular Joint Disorder
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: Cervical stabilization exercises|OTHER: Standard treatment (Education + home exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering Drugs
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: metformin|DRUG: repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma.
Status: RECRUITING
Conditions: Locally Advanced Unresectable or Metastatic Gastric Cancer|Locally Advanced Unresectable or Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma
Interventions: DRUG: M108 monoclonal antibody|DRUG: Placebo|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: BIOLOGICAL: AMG 714|BIOLOGICAL: Placebo|OTHER: Placebo Gluten Challenge|OTHER: Gluten Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Pi" and Hot Flushes
Status: COMPLETED
Conditions: Menopausal Symptom Relief
Interventions: DRUG: Capsicum frutescens fruits, homeopathic medicine|DRUG: Inert alcoholic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Pain and Increasing Comfort During a Retinopathy of Prematurity Examination
Status: NOT_YET_RECRUITING
Conditions: Pain|Retinopathy of Prematurity|Premature Baby 26 to 32 Weeks|Premature Baby 33 to 36 Weeks
Interventions: OTHER: baby massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Trial of Intramural Injection of DTI-015 for Recurrent Malignant Gliomas
Status: COMPLETED
Conditions: Glioma|Brain Neoplasms
Interventions: DRUG: DTI-015
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Electromyographic Activity of the Muscles of the Pelvic Floor Runners With Conventional Shoes and Minimalist.
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: COMBINATION_PRODUCT: Effect of pelvic floor for the use of minimalist shoes versus shod in woman.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Azopt Versus Placebo Added to Xalatan in Patients With Elevated Intraocular Pressure (IOP) on a Prostaglandin
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Brinzolamide 1% ophthalmic solution (Azopt)|DRUG: Placebo eye drops|DRUG: Latanoprost 0.005% ophthalmic solution (Xalatan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: CardioPumlonary Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection
Status: RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: S-217622|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals
Status: RECRUITING
Conditions: Healthy Individuals|Shellac Nail Polish|Oxygen Saturation|Nursing|Perioperative Care
Interventions: OTHER: Shellac nail polish application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Comparison of PENG/LFCN to FICB for Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: Pericapsular Nerve Group Block with Lateral Femoral Cutaneous Nerve Block|PROCEDURE: Fascia Iliaca Compartment Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metabolism of 0.35mg Norethindrone vs 5mg Norethindrone Acetate
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Norethindrone Acetate 5 MG|DRUG: Norethindrone 0.35 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess Safety, Tolerability, and Pharmacokinetics of AZD0186
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD0186|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop
Status: RECRUITING
Conditions: Oxygen Toxicity|COPD Exacerbation|Hyperoxia|Hypoxemia|Hypoxic Respiratory Failure
Interventions: DEVICE: FreeO2|OTHER: manual titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Oral combined hormonal contraceptives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified-Thoracolumbar Interfascial Plane Block and Erector Spinae Plane Block Following Lumbar Instrumentation Surgery
Status: WITHDRAWN
Conditions: Lumbar Spine Instability|Lumbar Spinal Stenosis|Lumbar Disc Disease|Lumbar Spine Degeneration
Interventions: DRUG: Erector spinae plane block (Group E)|DRUG: Modified-thoracolumbar interfascial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cinnamon Extract on Insulin Resistance in Polycystic Ovary Syndrome
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Cinnamon Supplementation|DIETARY_SUPPLEMENT: Placebo (wheat flour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma
Status: RECRUITING
Conditions: Pancreas Cancer|Cancer of the Pancreas|Pancreas Adenocarcinoma
Interventions: DEVICE: Adaptive stereotactic body radiation therapy|DRUG: Defactinib|PROCEDURE: Tumor biopsy|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropathic Pain in Elderly People With Diabetes: Impact on Quality of Life and Cognition
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Peripheral Neuropathy|Cognitive Impairment|Quality of Life|Diabetic Peripheral Neuropathic Pain
Interventions: BEHAVIORAL: Cambridge Neuropsychological Test Automated Battery (CANTAB)|OTHER: Chinese (Hong Kong) 12-item Short-Form Health Survey (version 2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors
Status: COMPLETED
Conditions: Brain Tumors|Central Nervous System Tumors|Neuroblastoma|Sarcoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: thiotepa|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Altered Ventilatory Control in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Fentanyl|PROCEDURE: Catheters|OTHER: Exercise|RADIATION: DEXA|OTHER: Pulmonary Function Tests|OTHER: Blood Draw|OTHER: Chemosensitivity Test|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brief Informational Intervention for COVID-19 Misinformation Prophylaxis
Status: COMPLETED
Conditions: COVID19 Behavioral Prophylaxis
Interventions: BEHAVIORAL: Brief informational infographic|BEHAVIORAL: Placebo control (non-behavioral infographic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Insufflation of Carbon Dioxide During Cardiac Surgery as Prevention Neurologic Complications
Status: UNKNOWN
Conditions: Air Embolism|Neurological Damage
Interventions: PROCEDURE: conventional prophylaxis of aeroembolism|PROCEDURE: conventional prophylaxis plus CO2 insufflation|PROCEDURE: cardiac surgery with opening of heart chambers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Effect of EFT on Psychological States in a Veterans Population
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Emotional Freedom Techniques (EFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neuromuscular Electrical Stimulation in the Critically Ill
Status: WITHDRAWN
Conditions: Polyneuropathy
Interventions: DEVICE: Gymna Belgium, DUO 400 (Neuromuscular electrical stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD)
Status: TERMINATED
Conditions: Graft-versus-Host Disease
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Combined VisioCyt Test and FGFR3 Mutations on a Urinary Sample to Diagnose Bladder Tumors
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DIAGNOSTIC_TEST: Urine collection (150ml)|OTHER: Blood sample (20 ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-Response-Study With a Recombinant Cocktail of Phleum (rPhleum) Allergens
Status: COMPLETED
Conditions: Type I-Allergy
Interventions: DRUG: placebo|BIOLOGICAL: rPhleum|BIOLOGICAL: rPhleum|BIOLOGICAL: rPhleum|BIOLOGICAL: rPhleum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
Status: RECRUITING
Conditions: Thyroid Gland Carcinoma
Interventions: PROCEDURE: Diagnostic Procedure|OTHER: Electronic Health Record Review|PROCEDURE: Needle Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Obstetric Antiphospholipid Antibody Syndrome : Contribution of the Evaluation of ADAMTS13 Made at the Diagnosis of Pregnancy on Evaluation the Risk of Pre-eclampsia
Status: COMPLETED
Conditions: Antiphospholipid Antibody Syndrome in Pregnancy
Interventions: OTHER: To study the prognostic value on the occurrence of pre-eclampsia, ADAMTS13 (ADAMTS13 protein and autoantibodies) in patients diagnosed with oAPS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily-Dose Consensus Interferon and Ribavirin: Efficacy of Combined Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Daily Infergen (Interferon Alfacon-1, CIFN) (9 or 15 µg) + Ribavirin (1000-1200 mg, based on body weight) PO Daily for up to 48 wks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of 18F-FLT PET
Status: TERMINATED
Conditions: CNS Brain Metastasis|Head and Neck Cancer|Lung Cancer|Prostate Cancer|Esophageal Cancer
Interventions: PROCEDURE: Imaging with 18F-FLT PET|PROCEDURE: Imaging with 18F-FLT PET|PROCEDURE: Imaging with 18F-FLT PET|PROCEDURE: Imaging with 18F-FLT PET|PROCEDURE: Imaging with 18F-FLT PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating CBT Delivered by Community Health Workers on Maternal Mental Health and Infant Cognitive Development in Insecure Environments
Status: UNKNOWN
Conditions: Maternal Anxiety|Maternal Depression|Infant Cognitive Development
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: tipranavir|DRUG: ritonavir|DRUG: saquinavir|DRUG: amprenavir|DRUG: lopinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Blasts 20 Percent or More of Bone Marrow Nucleated Cells|High Risk Myelodysplastic Syndrome|Recurrent Acute Biphenotypic Leukemia|Recurrent Acute Myeloid Leukemia|Recurrent High Risk Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory High Risk Myelodysplastic Syndrome
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Surgery Recovery in Infants Assessed Using Neoneur Feeding System
Status: NOT_YET_RECRUITING
Conditions: Neonatal Disease|Post-Surgical Complication|Cardiac Disease
Interventions: DEVICE: Neoneur Feeding System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Against Atherosclerosis in Patients With Overweight Problems or Obesity
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: BIOLOGICAL: atherosclerosis vaccine|BIOLOGICAL: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Deep Sedation for Ablation Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Ablation|Sedation|Propofol|Dexmedetomidine
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of XTR004 as a Novel 18F-labeled PET MPI Tracer in Diagnosis of Known or Suspected CAD
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: XTR004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study of CKD-810 and Taxotere to Treat Patient With Advanced Solid Cancer
Status: COMPLETED
Conditions: Advanced Solid Cancers
Interventions: DRUG: CKD-810, Taxotere inj.|DRUG: CKD-810, Taxotere inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Oral Intervention in Patients With AMI
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Dental Diseases
Interventions: PROCEDURE: active dental procedure|DRUG: post-myocardial infarction management|RADIATION: basic periodontal examinations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Efficacy of a Non-hormonal Drug Against Endometriosis Associated Pelvic Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: CCR1-Antagonist (BAY86-5047, ZK811752)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Zotiraciclib for Recurrent High-Grade Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
Status: RECRUITING
Conditions: Brain Tumor|Cancer
Interventions: DRUG: Zotiraciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Add-on Therapy of Wuling Capsule in Epilepsy Patients With Depression
Status: COMPLETED
Conditions: Epilepsy|Depression
Interventions: DRUG: wuling capsule|DRUG: placebo of wuling capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Neuromuscular Disease|Chest Wall Disorders|Obesity Hypoventilation Syndrome
Interventions: DEVICE: Telemonitoring tools|DEVICE: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT