pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evolution of Muscle Function, Breathlessness and Quality of Life Following Intra or Extra-Abdominal Sepsis in ICU Patients
Status: RECRUITING
Conditions: Sepsis|Septic Shock
Interventions: OTHER: Ultrasound measurement of the diaphragm and intercostals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Additional Efficacy, and Safety of Olmesartan Medoxomil 20mg / Hydrochlorothiazide 12.5mg in the Treatment of Chinese Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: olmesartan medoxomil + hydrochlorothiazide|DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Quetiapine Fumarate Tablets 25 mg Under Fed Condition
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: Quetiapine Fumarate Tablets 25 mg|DRUG: Quetiapine Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Metastatic Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Immunological Evaluation of Belimumab Plus Low Dose IL-2 in the Treatment of Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Protein Metabolism and Insulin Sensitivity in Overweight Individuals: Effects of Meals With Various Fatty Acid Compositions
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Saturated fat|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Fish Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Intervention Program for the Trunk Neuromuscular Pattern and Postural Control in Pregnant With Low Back Pain
Status: COMPLETED
Conditions: Pregnancy Complications|Low Back Pain
Interventions: OTHER: Specific exercises for lumbar stabilization|OTHER: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Post Marketing Surveillance Study Of Doxazosin Mesylate GITS Among Filipino Patients With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Doxazosin mesylate GITS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Brain Injuries|Disorder of Consciousness|Stroke|Spasticity as Sequela of Stroke|Contracture|Hypertonic Disorder|Central Nervous System Diseases|Pathologic Processes|Craniocerebral Trauma|Trauma, Nervous System|Neurocognitive Disorders
Interventions: DEVICE: Real soft splint (6 cm)|DEVICE: Placebo soft splint (1 cm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Topotecan|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: nitric oxide gel|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: SAGE-718|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus|Endocrine System Diseases|Nutritional and Metabolic Diseases
Interventions: DRUG: JNJ16269110|DRUG: JNJ16269110|DRUG: JNJ16269110|DRUG: Placebo|DRUG: Metformin|OTHER: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus/Sorafenib or Sunitinib in Patients With Metastatic Renal Cell Carcinoma (RCC)
Status: WITHDRAWN
Conditions: Locally Metastatic Malignant Neoplasm
Interventions: DRUG: Everolimus and sorafenib|DRUG: Sunitinib monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: Creatine Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Carmustine; Cytarabine, Etoposide, & Melphalan; Stem Cell Transplantation for Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: carmustine|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial on the Treatment Effects of Melatonin and Light Therapy on Delayed Sleep Phase Syndrome
Status: COMPLETED
Conditions: Delayed Sleep Phase Syndrome
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: Bright light|OTHER: Placebo red light|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Bailout Intracranial Angioplasty Following Thrombectomy for Acute Large Vessel Occlusion
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Bailout angioplasty|PROCEDURE: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SGB-3908 in Healthy Subjects and Mildly Hypertensive Subjects
Status: NOT_YET_RECRUITING
Conditions: Hypertension,Essential
Interventions: DRUG: SGB-3908|OTHER: SGB-3908-Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Postmastectomy Pain Syndrome With Fat Grafting
Status: COMPLETED
Conditions: Post-Mastectomy Chronic Pain Syndrome (Disorder)
Interventions: PROCEDURE: Liposuction|PROCEDURE: Fat graft|PROCEDURE: Sham graft (saline injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Effect of the Organic Anion Transporter Inhibitor Probenecid on the Pharmacokinetics of JNJ-64041575 in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-64041575|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of IntraVascular UltraSound Guidance on the Outcomes of Xience Prime Stents in Long Lesions (IVUS-XPL Study): Retrospective and Prospective Follow-up Study
Status: RECRUITING
Conditions: Myocardial Ischemia(Implanted Drug-eluting Stents Because of Ischemic Heart Disease(Stable Angina, Acute Coronary Syndrome))
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: : A Comparison of Neuromuscular Transmission in the Muscles During General Anesthesia
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DEVICE: TOF Cuff on arm|DEVICE: TOF Cuff on lower leg|DEVICE: TOF Scan on toe|DEVICE: TOF Scan on adductor pollicis|DEVICE: TOF Scan on corrugator supercilii
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rigid Taping and Patella Stabilizing Brace Methods in pwPFPS (Patient With Patellofemoral Pain Syndrome)
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: McConnell taping|DEVICE: Patella Stabilizer Brace
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees
Status: COMPLETED
Conditions: Lower Limb Amputation Above Knee (Injury)
Interventions: DEVICE: Microprocessor Knee (MPK)|DEVICE: Non-Microprocessor Knee (NMPK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Immunosuppressive Drugs in Heart Transplant Patients
Status: COMPLETED
Conditions: Heart Transplant
Interventions: DRUG: cyclosporine, tacrolimus, mycophenolate mofetil and everolimus (immunosuppressive drugs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proposal for Intraoperative Administration of Intravenous Indocyanine Green to Evaluate Position of the Optic Canal, Position of the Internal Carotid Arteries, Tumor Vascularization, and Vessel Encasement in Endoscopic Endonasal Cranial Base Surgery
Status: COMPLETED
Conditions: Skull Base Neoplasms|Skull Neoplasms|Bone Neoplasm|Neoplasms|Bone Diseases|Musculoskeletal Disease
Interventions: DEVICE: near-infrared light nasal endoscope used with ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of the Therapeutic Vaccine GI-5005 Combined With Pegylated Interferon Plus Ribavirin Standard of Care Therapy Versus Standard of Care Alone in Patients With Genotype 1 Chronic Hepatitis C Infection
Status: COMPLETED
Conditions: Genotype 1 Chronic Hepatitis C
Interventions: DRUG: GI-5005|DRUG: Pegylated Interferon and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VX15/2503 in Combination With Ipilimumab or Nivolumab in Patients With Head and Neck Cancer
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: VX15/2503|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Everolimus|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Modulation of Motivational Brain Regions in Healthy Volunteers
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Anger Management Treatment in Reducing Anger-Related Behaviors in Female Juvenile Offenders
Status: COMPLETED
Conditions: Anger
Interventions: BEHAVIORAL: Juvenile Justice Anger Management (JJAM) for Girls|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Exercise-Induced Hypoalgesia in Upper and Lower Limbs: A Randomized Controlled Trial in Healthy Individuals
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: OTHER: Aerobic exercise|OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenteric Approach vs. Conventional Approach for Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreaticoduodenectomy|Mesenteric Approach
Interventions: PROCEDURE: pancreaticoduodenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate The Safety and Effectiveness of Performing 0.50 Diopter Astigmatism Correction on the Commercially Available RxSight Light Adjustable Lens (LAL)
Status: COMPLETED
Conditions: Aphakia|Cataract
Interventions: DEVICE: Light Delivery Device (LDD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Analysis of "Genotype-phenotype" Correlations Observed in a Large Cohort of Patients With Hereditary Retinal Dystrophies - GEPHIRD
Status: RECRUITING
Conditions: Hereditary Retinal Dystrophies
Interventions: PROCEDURE: OCT-A|PROCEDURE: Visual acuity (ETDRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ependymoma
Interventions: RADIATION: Irradiation|PROCEDURE: Surgery|DRUG: ^1^8F-Fluorodeoxyglucose|DRUG: ^1^1C-methionine|DEVICE: Photon therapy|DEVICE: Proton therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Out-of-hospital Cardiac Arrest (OHCA) Biomarkers
Status: COMPLETED
Conditions: Neurological Outcome|Cardiac Arrest|Out-Of-Hospital Cardiac Arrest|Brain Anoxia Ischemia|Hypoxia, Brain|Hypoxia-Ischemia, Brain|Cardiac Arrest With Successful Resuscitation|Cardiac Arrest, Out-Of-Hospital|Brain Injuries
Interventions: PROCEDURE: blood draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study for the Treatment of Heart Failure With Preserved Ejection Fraction Associated With High Blood Pressure Using Right Atrial Pacing Controlled by the PressurePaceTM System
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)|Hypertension
Interventions: DEVICE: BaroPacing treatment|DEVICE: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Pain Intensity of the Patients Who Had Undergone Abdominal Surgery With a Midline Incision
Status: COMPLETED
Conditions: Transcutaneous Electric Nerve Stimulation
Interventions: OTHER: TENS|OTHER: TAES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Long-term Safety Study of Cannabidiol Oral Solution (GWP42003-P, CBD-OS) in Patients With Rett Syndrome
Status: TERMINATED
Conditions: Rett Syndrome|RTT
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety & Immunogenicity of GSK Biologicals' Boostrix (dTpa) Vaccine vs. Chinese DT Vaccine
Status: COMPLETED
Conditions: Diphtheria|Acellular Pertussis|Tetanus
Interventions: BIOLOGICAL: Boostrix|BIOLOGICAL: Chinese DT vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells as an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: BIOLOGICAL: Allogeneic umbilical cord mesenchymal stem cells|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCAR Burden of Left Atrium Guided cathEter Ablation sTrategy for Persistent Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: LVA-guided LA substrate modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
Status: COMPLETED
Conditions: Sleep Disorders|Obstructive Sleep Apnea|Major Depressive Disorder|Dysthymic Disorder
Interventions: DRUG: armodafinil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Venoplasty|PROCEDURE: Sham procedure (non-treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of an Approved Drug With a Statin (a Medication That Lowers Cholesterol Levels) as Compared to Statin Therapy Alone in Patients With High Cholesterol (0653-040)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: statins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetic/Pharmacodynamic Properties and Safety of Leucostim® Compared to Neupogen® in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Leucostim®|DRUG: Neupogen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Dyskinesias in Parkinson's Disease and Their Relation to Levodopa Pharmacokinetics
Status: COMPLETED
Conditions: Parkinson Disease|Dyskinesias
Interventions: DRUG: levodopa/carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Effects on Mayor Adverse Cardiovascular Events in Patients With Acute Myocardial Infarction (DAPA-AMI)
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Cardiovascular Morbidity|Heart Failure|Angina, Unstable
Interventions: DRUG: Dapagliflozin 10Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency
Status: RECRUITING
Conditions: Severe Combined Immunodeficiency, X-Linked
Interventions: DRUG: Lentiviral vector transduced CD34+ cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of MBX-102 in Treatment of Hyperuricemia in Patients With Gout
Status: COMPLETED
Conditions: Hyperuricemia|Gout
Interventions: DRUG: Arhalofenate|DRUG: Arhalofenate|DRUG: Placebo comparator|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study of rhBMP-2/ACS/LT-CAGE® Device for Anterior Lumbar Interbody Fusion in Patients With Symptomatic Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/ACS/LT-CAGE® Device|DEVICE: Autogenous Bone/LT-CAGE® Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of RestoreX Penile Traction Therapy In Preserving Erectile Function Post-Prostatectomy
Status: RECRUITING
Conditions: Erectile Dysfunction Following Radical Prostatectomy
Interventions: DEVICE: RestoreX 1-6 months (randomized phase)|DEVICE: RestoreX 6-9 months (open label phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth Ventricle or Resection Cavity in Children and Adults With Recurrent or Residual Posterior Fossa Ependymoma
Status: RECRUITING
Conditions: Fossa Ependymoma
Interventions: DRUG: 5-Azacytidine and trastuzumab infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy of Zinc Oxide Nanoparticles Coated Socks in Prevention of Unpleasant Foot Odor
Status: COMPLETED
Conditions: Zinc Oxide|Foot Dermatoses
Interventions: OTHER: zinc oxide nanoparticles coated socks|OTHER: placebo socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: GW427353|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children
Status: COMPLETED
Conditions: Heart Transplant|Small Intestine Transplant|Kidney Transplant|Liver Transplant|EBV-Related PTLD|PTLDs
Interventions: PROCEDURE: transplant|DRUG: Immunosuppressive Drugs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Efficacy and Safety Study in Patients With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Active Ulcerative Colitis
Interventions: DRUG: Asacol®|DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimization of a Low-dose CT Protocol in Patients With Suspected Uncomplicated Acute Appendicitis and BMI >30
Status: SUSPENDED
Conditions: Appendicitis|Other and Unspecified Acute Appendicitis|Acute Disease|Gastrointestinal Disease|Intra-abdominal Infection
Interventions: RADIATION: Low-dose CT|PROCEDURE: Laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CryoSpray Ablation of Low Grade or High Grade Dysplasia Within Barrett's Esophagus
Status: TERMINATED
Conditions: Barrett's Esophagus|High Grade Dysplasia|Low Grade Dysplasia
Interventions: DEVICE: CryoSpray Ablation System (510(k) NO: K070893)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemotherapy for Recurrent T3/T4 Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Safety, Tolerability, And Pharmacokinetics Of Multiple Doses Of PF-05180999 In Healthy Adults
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: Placebo Tablets|DRUG: PF-05180999 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound
Status: UNKNOWN
Conditions: Atelectasis
Interventions: DRUG: S-ketamine|DRUG: normal saline group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome
Status: RECRUITING
Conditions: Fragile X Syndrome
Interventions: DRUG: ZYN002 - transdermal gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Duration High Intensity Intrapleural Alteplase With Pulmozyme in Pleural Infection Management
Status: COMPLETED
Conditions: Loculated Empyema
Interventions: DRUG: Intra-pleural Alteplase 16mg with Pulmozyme (DNase) 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Suspected Preeclampsia Based on 6-hour Versus 24-hour Urine Protein Collection
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: Six-hour urine protein collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Augmenting Buried in Treasures Workshop (BIT) With In-home Decluttering Practice for Individuals With Hoarding Disorder
Status: COMPLETED
Conditions: Hoarding Disorder
Interventions: BEHAVIORAL: BIT+in-home decluterring|BEHAVIORAL: In-Home Decluttering
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Quality of Life in Older vs. Younger Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Hematopoietic Cell Transplant
Interventions: BEHAVIORAL: ePRO survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Hepato-celiac lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy
Status: NOT_YET_RECRUITING
Conditions: Vaginal Atrophy|Genitourinary Syndrome of Menopause|Vulvar Atrophy
Interventions: DRUG: Oxytocin|OTHER: Hydroxypropyl methylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection
Interventions: DEVICE: False Lumen Embolization System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
Status: COMPLETED
Conditions: Bradycardia|Hypoxemia
Interventions: OTHER: NPO with Nose-close and Abdomen-compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Self Injurious Behavior: A Novel Brain Stimulation Approach
Status: COMPLETED
Conditions: Self-Injurious Behavior|Self Harm|Self-injury|Self-inflicted Injury|Self Injurious Behavior Without Suicidal Intent|Non-Suicidal Self Injury|Non Suicidal Self Inflicted Injury|Cutting|Depression|Bipolar Disorder|Borderline Personality Disorder
Interventions: DEVICE: Transcranial direct current stimulation|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Onartuzumab in Combination With Erlotinib in Patients With MET-Positive Stage IIIB or IV Non-Small Cell Lung Cancer Carrying an Activating Epidermal Growth Factor Receptor (EGFR) Mutation
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib|DRUG: onartuzumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Warm Bupivacaine on Supraclavicular Plexus Block Characteristics
Status: COMPLETED
Conditions: Surgery to the Distal One Third of the Upper Limb
Interventions: DRUG: Warm bupivacaine at (37°c)|DRUG: Bupivacaine at operating room temperature (23°c)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Guided Inguinal Indocyanine Green Injection to Identify and Pre-emptively Seal Lymphatic Leaks
Status: NOT_YET_RECRUITING
Conditions: Lymphocele|Prostate Cancer
Interventions: DRUG: ICG injection|OTHER: Non-Injection/Control|PROCEDURE: Prostatectomy with pelvic lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Probiotics in Treatment of Pediatric NAFLD Patients by Assessing With Fibroscan
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Culturelle (Lactobacillus rhamnosus strain GG)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vascular Changes Due to Different Treatments of Lymphedema Secondary to Postoperative Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Lymphedema
Interventions: OTHER: therapeutic exercises|OTHER: elastic compression|OTHER: functional compressive bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Oral Health for Healthy Cognitive Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Malocclusion|Dementia
Interventions: PROCEDURE: Dental occlusion restoration|PROCEDURE: Orthodontic treatment of malocclusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women.
Status: COMPLETED
Conditions: Energy Expenditure
Interventions: DIETARY_SUPPLEMENT: One-A-Day Weight S.A. (Multi-Vitamins, BAY94-9350)|DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Metaverse-Based Immersive Technology Intervention for Oral Health Education: A Quasi-Experimental Study
Status: RECRUITING
Conditions: Knowledge, Attitudes, Practice
Interventions: OTHER: Oral health education lecture|OTHER: Oral health education via mHealth on WhatsaApp|OTHER: Oral health education via Metaverse platform on Meta-OHE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Subclavian Versus Inferior Vena Cava Collapsibility Indices.
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DIAGNOSTIC_TEST: inferior vena cava collapsibility|DIAGNOSTIC_TEST: subclavian vein collapsibility|DIAGNOSTIC_TEST: central venous pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Study of Postieror Ankle Fracture
Status: UNKNOWN
Conditions: Postieror Malleolar Fracture|Treatment
Interventions: PROCEDURE: Plate fixation|PROCEDURE: Screw fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Status: COMPLETED
Conditions: Presbyopia
Interventions: COMBINATION_PRODUCT: Pilocarpine Ophthalmic administered with the Optejet dispenser|COMBINATION_PRODUCT: Placebo administered with the Optejet dispenser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations
Status: TERMINATED
Conditions: Upper Tract Urothelial Carcinomas|Urothelial Bladder Cancer
Interventions: DRUG: Infigratinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke
Status: UNKNOWN
Conditions: Stroke|Hemiparesis
Interventions: DEVICE: NeuroExo co-robot neurorehabilitation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients
Status: RECRUITING
Conditions: Mesenchymal Stem Cell|COVID-19 Pneumonia
Interventions: BIOLOGICAL: umbilical cord mesenchymal stem cells|DRUG: paxlovid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Arformoterol (Brovana)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Known Antihypertensive Drug Telmisartan on Red Blood Cells and Circulation in the Smallest Blood Vessels
Status: TERMINATED
Conditions: Arterial Hypertension|Diabetes Mellitus Type 2 IRC or NIR
Interventions: DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Muscle Relaxation-study
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic
Interventions: DRUG: Rocuronium|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Headache Study to Compare Aggrenox Full Dose and Reduced Dose
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DRUG: Aggrenox® modified release capsules|DRUG: Aggrenox® modified release capsules matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Collect Data for Neonatal Abstinence Syndrome (NAS) and Evaluate the Automated Data Collection Process
Status: ENROLLING_BY_INVITATION
Conditions: Neonatal Abstinence Syndrome
Interventions: DEVICE: Neomonki
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Phase I Study of Oral UE2343 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: UE2343|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Early Mobilization and Endurance Training for Patients With Prolonged Mechanical Ventilator
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: OTHER: Early Mobilization and endurance training|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Trial to Assess Safety and Immunogenicity of V590 (COVID-19 Vaccine) in Healthy Adults (V590-001)
Status: TERMINATED
Conditions: Coronavirus Disease (COVID-19)
Interventions: BIOLOGICAL: V590|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: TMC647055|DRUG: TMC435|DRUG: Ritonavir|DRUG: Ribavirin|DRUG: Pegylated interferon alpha-2a (PegIFN)|DRUG: GSK2336805
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery Program After a Robotic-assisted Surgery (RAAC) of Radical Prostatectomy. PROSTA-RAAC
Status: COMPLETED
Conditions: Prostate Cancer|Quality of Life|Recovery Programm
Interventions: BEHAVIORAL: Follow-up patient program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin in Treatment of Postdural Puncture Headache
Status: RECRUITING
Conditions: Postdural Puncture Headache
Interventions: DRUG: Pregabalin 75mg|BIOLOGICAL: An epidural blood patch (EBP)|COMBINATION_PRODUCT: conservative treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Placebo|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
Status: COMPLETED
Conditions: Protruded Disk
Interventions: OTHER: CLARIX™100|OTHER: CLARIX CORD 1K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream
Status: COMPLETED
Conditions: Tattoo|Acne Keloidalis Nuchae
Interventions: DRUG: 2,5% lidocaine / 2,5% prilocaine cream|DRUG: 7% lidocaine / 7% tetracaine cream|DEVICE: Neodymium-doped yttrium aluminium garnet (Nd:Yag) laser|DEVICE: Q-switched nd Yag laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRIDE - Pilot Trial of an Online Digital Problem-solving Intervention for School-going Adolescents in Goa, India
Status: COMPLETED
Conditions: Mental Health Issue|Depression, Anxiety|Stress
Interventions: BEHAVIORAL: POD Adventures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Pouchitis
Status: RECRUITING
Conditions: Pouchitis
Interventions: OTHER: Fecal microbiota transplantation|OTHER: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib Followed by High-Dose Melphalan and Bortezomib as Conditioning Regimen for Tandem Stem Cell Transplants
Status: COMPLETED
Conditions: Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: Bortezomib|DRUG: Melphalan|PROCEDURE: PBSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunoregulatory Effect of Microparticle Delivered STING Agonist in the Control of Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS)
Status: RECRUITING
Conditions: Relapse Remitting Multiple Sclerosis
Interventions: OTHER: Blood Draw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Fiber in the Prevention and Treatment of Fecal Incontinence
Status: RECRUITING
Conditions: Fecal Incontinence|Irritable Bowel Syndrome With Diarrhea
Interventions: DIETARY_SUPPLEMENT: Psyllium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Circulating Fetal DNA, Pregnancy And Immune Diseases"
Status: UNKNOWN
Conditions: Autoimmune Diseases|Pregnancy
Interventions: BIOLOGICAL: the detection of the risk of fetal trisomy 21 by blood tests : free fetal DNA circulant analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Who Participated in Rilpivirine Pediatric Studies
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus Type 1
Interventions: DRUG: Rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS in Treatment of Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: repetitive transcranial magnetic stimulation|DEVICE: sham (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cardiac Resynchronization Therapy (CRT) on Left Ventricular Assist Device (LVAD) Function
Status: UNKNOWN
Conditions: LVAD (Left Ventricular Assist Device) Driveline Infection
Interventions: OTHER: Temporary changes in an already-implanted medical device (biventricular pacemaker)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Moderately to Severely Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Arthritis|Psoriatic
Interventions: DRUG: adalimumab|DRUG: placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Haemodialysis in Sleep Apnoea
Status: COMPLETED
Conditions: Sleep Apnoea|Renal Failure|End Stage Kidney Disease|Sleep Disturbance|Sleep Disorders|Sleep
Interventions: PROCEDURE: Haemodiafiltration post-dilution model|PROCEDURE: Haemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Neurogabin-M (Gabapentin 400 mg) Capsule With Parketin (Gabapentin 400 mg) Capsules
Status: COMPLETED
Conditions: Healthy Volunteers|Bioequivalence Study
Interventions: DRUG: Neurogabin (Gabapentin) 400 mg capsule|DRUG: Parketin (Gabapentin) 400 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dorsal Nerve Block and Caudal Block in Hypospedius Repair in Children
Status: NOT_YET_RECRUITING
Conditions: Dorsal Nerve Block in Hypospiudus
Interventions: DRUG: Marciane|DRUG: Marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT