pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Renal Toxicity of Iodixanol and Iopromide in Patients With Renal Dysfunction
Status: UNKNOWN
Conditions: Kidney Failure, Chronic
Interventions: DRUG: iodixanol|DRUG: iopromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Measurement of NAD+ Synthesis in Human Skeletal Muscle
Status: ACTIVE_NOT_RECRUITING
Conditions: Skeletal Muscle
Interventions: OTHER: Deuterated nicotinamide (D4-NAM) IV infusion|PROCEDURE: Skeletal muscle biopsy|PROCEDURE: Skin tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation
Status: COMPLETED
Conditions: Energy Metabolism|Athletic Performance
Interventions: BEHAVIORAL: Test in the morning|BEHAVIORAL: Test in the afternoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Dolutegravir on Etonogestrel Levels in HIV-infected Women in Botswana
Status: COMPLETED
Conditions: Contraceptive Usage|HIV Infections|Drug Interaction
Interventions: DRUG: dolutegravir|DEVICE: ENG implant|DRUG: Efavirenz
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma
Status: COMPLETED
Conditions: Osteosarcoma
Interventions: DRUG: Cisplatin|DRUG: Doxorubicin|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Receptor Polymorphisms and Efficacy of Vitamin D-Fortified Yogurt Drink in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Fortified Yogurt Drink|DIETARY_SUPPLEMENT: Plain Yogurt Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Dextrose Therapy on Physical Therapy in Subdeltoid Bursitis
Status: NOT_YET_RECRUITING
Conditions: Subdeltoid Bursitis|Injection|Effect of Drug
Interventions: DRUG: Dextrose|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sustained Release Dalfampridine in Transverse Myelitis (Re-Launch)
Status: COMPLETED
Conditions: Transverse Myelitis|Neuromyelitis Optica|Idiopathic Transverse Myelitis|Myelitis NOS
Interventions: DRUG: Dalfampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Beta- Plus Auger Electron Therapy Using a Novel Somatostatin Receptor Subtype 2 Antagonist Labelled With Terbium-161 (161Tb-DOTA-LM3)
Status: RECRUITING
Conditions: Neuroendocrine Neoplasia's (NENs)|Gastroenteropancreatic Neuroendocrine Tumour (GEP-NET)
Interventions: DRUG: 161Tb-DOTA-LM3|DRUG: 177Lu-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CYP2D6 Genotype-guided Management of Opioid Analgesics in Patients Undergoing Elective Ventral Hernia Repairs
Status: NOT_YET_RECRUITING
Conditions: Ventral Hernia
Interventions: OTHER: Opioid pain medication prescribed based on CYP2D6 genotype testing PLUS Acetaminophen and Gabapentin|OTHER: Acetaminophen and Gabapentin: standard postoperative pain medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)
Status: RECRUITING
Conditions: Urinary Incontinence in Children
Interventions: DRUG: Solifenacin|DRUG: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Predictive Value of Ureteral Jet Assessment With Ultrasound in Patients Presenting With Acute Renal Colic
Status: COMPLETED
Conditions: Ureteral Calculi
Interventions: DEVICE: renal and bladder ultrasound with ureteral jet assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laser Acupuncture Versus Tap Water Iontophoresis on Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DEVICE: Laser Acupoint|DEVICE: Tap water iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of RHEOpheresis in the Treatment of Peripheral Artery Disease in Hemodialysis Patients
Status: RECRUITING
Conditions: Hemodialysis
Interventions: PROCEDURE: Rheopheresis procedure|BIOLOGICAL: Blood Sample|PROCEDURE: Shamapheresis procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Barriers to Rectal Irrigation in Defaecatory Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Defecation Disorder|Constipation - Functional|Constipation by Outlet Obstruction|Faecal Incontinence|Faecal Smearing|Obstructive Defecation Syndrome
Interventions: OTHER: There is no intervention. This a qualitative study to explore barriers to rectal irrigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and PK of Escalating Doses of Flufirvitide-3 Dry Powder for Inhalation in Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Flufirvitide 3|DRUG: Placebo for Flufirvitide-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial for Subjects With Systemic Lupus Erythematosus Who Have Completed Protocol AN-SLE3321
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: A-623|DRUG: A-623|DRUG: A-623
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab in the First Episode of Paediatric Nephrotic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Steroid-Sensitive Nephrotic Syndrome
Interventions: DRUG: Rituximab|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis
Status: NOT_YET_RECRUITING
Conditions: Photobiomodulation|Stomatitis, Aphthous
Interventions: DEVICE: Gemini laser|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Quetiapine Fumarate|DRUG: Escitalopram oxylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Passive Heat Treatment on Glycaemic Response During an Oral Glucose Tolerance Test in Diabetic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Infrared sauna heating|DEVICE: Sham sauna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Alcohol-Related Hepatitis With Arginine
Status: WITHDRAWN
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Surufatinib Combined With Toripalimab in the Treatment of Peritoneal Metastatic Carcinoma of Gastrointestinal or Primary Peritoneal Cancer
Status: UNKNOWN
Conditions: Refractory Metastatic Digestive System Carcinoma|Primary Peritoneal Cancer
Interventions: DRUG: Surufatinib/Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population
Status: RECRUITING
Conditions: Cataracts Infantile
Interventions: DRUG: Clobetasol Propionate|DRUG: Prednisolone acetate ophthalmic suspension, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baroreflex Activation Therapy in Left Ventricular Assist Device Patients Study
Status: RECRUITING
Conditions: Congestive Heart Failure
Interventions: DEVICE: Baroreflex Activation Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel
Status: COMPLETED
Conditions: CYP2C19 Genotypes
Interventions: DRUG: Proguanil|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Immunotherapy in Autoantibody Positive Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Psychosis|Auto Immune Disorders
Interventions: BIOLOGICAL: Plasma Exchange|BIOLOGICAL: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Omeprazole on the Pharmacokinetics of Dasatinib in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dasatinib + Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cell Tracking Using Superparamagnetic Particles of Iron Oxide (SPIO) and Magnetic Resonance Imaging (MRI) - A Pilot Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: Administration of autologous Endorem-labelled mononuclear cells intravenously|DRUG: Administration of Endorem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mama Empoderada: Adapting a Novel Mental Health Prevention Intervention for Migrant Mothers With Young Children
Status: NOT_YET_RECRUITING
Conditions: Interventional
Interventions: BEHAVIORAL: Mama Empoderada [Mom Power]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Regulation of Intestinal and Hepatic Lipoprotein Production by Glucose and Fructose
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: OTHER: Intraduodenal glucose or fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Oketani Massage on Breastfeeding Success and Breast Engorgement in Mothers Delivering by Cesarean Section
Status: COMPLETED
Conditions: Breastfeeding|Engorgement of Breast Associated With Childbirth, Postpartum
Interventions: OTHER: Oketani massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Two Physiotherapy Intervention Methods Applied in Subjects in the Social-healthcare Setting With Nonspecific Neck Pain.
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Electrotherapy-Transcutaneous Electrical Stimulation (TENS)|OTHER: Massage therapy|OTHER: Stretching exercises|OTHER: Ischaemic Compression Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Carotid Occlusion Surgery Study
Status: TERMINATED
Conditions: Stroke|Ischemic Attack, Transient|Cerebral Infarction
Interventions: PROCEDURE: extracranial-intracranial bypass surgery|DRUG: best medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Observational Study to Define HBsAg Loss With or Without Seroconversion to antiHBs in Patients With Chronic Hepatitis by B Virus Treated With Nucleoside/Nucleotide Analogs
Status: COMPLETED
Conditions: Chronic Hepatitis B Treated With Nucleoside/Nucleotide Analogues
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Assisted Sit-up Exercise vs Swiss Ball Pikes on Postpartum Low Back Pain.
Status: COMPLETED
Conditions: Postpartum Disorder|Lumbar Pain Syndrome|Activation, Patient
Interventions: OTHER: assisted sit-up exercises|OTHER: swiss ball pikes exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Tone Power Therapy for Hemiparetic Cerebral Palsy Children
Status: NOT_YET_RECRUITING
Conditions: Hemiparetic Cerebral Palsy Children
Interventions: DEVICE: high tone power therapy|OTHER: traditional physical therapy exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of ZIO-101 in Hematologic Cancers
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Myeloproliferative Disease|Chronic Lymphoproliferative Disease|Multiple Myeloma|Lymphoma|Poor-risk Myelodysplasia (MDS)
Interventions: DRUG: ZIO-101 (Darinaparsin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG vs Intra-articular Injection for Hip Arthroscopy
Status: RECRUITING
Conditions: Opioid Use|Acute Pain
Interventions: PROCEDURE: Pericapsular nerve group block|PROCEDURE: Intra-articular local anesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Balloon Angioplasty Versus Everolimus Platinum Chrome Stent
Status: UNKNOWN
Conditions: Percutaneous Coronary Intervention (PCI)|Coronary Artery Disease (CAD)|De Novo Stenosis
Interventions: DEVICE: DEB for de Novo Lesions|DEVICE: DES for de Novo Lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma
Status: TERMINATED
Conditions: Metastatic Ocular Melanoma|Metastatic Uveal Melanoma
Interventions: DRUG: Aldesleukin|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Young Tumor Infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-091)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: MK0869, aprepitant|DRUG: Comparator: ondansetron IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Partners in Wellness: Evaluation of a Pay for Performance Program for High-Utilizers of Mental Health Services
Status: COMPLETED
Conditions: Psychotic Disorders|Bipolar Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Pay For Performance (PFP)|BEHAVIORAL: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of T-MSAT on Inpatients With Acute Low Back Pain Caused by Traffic Accidents : A Randomized Controlled Trial
Status: COMPLETED
Conditions: Low Back Pain|Medicine, Korean Traditional
Interventions: PROCEDURE: T-MSAT(Motion style acupuncture treatment using traction)|PROCEDURE: Korean medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplant for Congenital Pediatric Disorders
Status: COMPLETED
Conditions: Congenital Pediatric Disorders
Interventions: DRUG: Busulfan|DRUG: Cytoxan|DRUG: Fludarabine|PROCEDURE: Cord Blood Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Anaplastic Large Cell Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Classic Hodgkin Lymphoma|Recurrent Mycosis Fungoides|Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified|Refractory Anaplastic Large Cell Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma|Refractory Mycosis Fungoides|Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified
Interventions: BIOLOGICAL: Anti-CD30/CD16A Monoclonal Antibody AFM13|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Fludarabine Phosphate|BIOLOGICAL: Genetically Engineered Lymphocyte Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circulating Androgen Levels Are Not Affected by the Administration of Vaginal Micronized Progesterone for Withdrawal Bleeding in Patients With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Anovulation|Polycystic Ovary Syndrome|Hyperandrogenism
Interventions: DRUG: Micronized Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
Status: COMPLETED
Conditions: Head Trauma|Craniocerebral Injuries|Crushing Skull Injury|Head Injuries|Head Injuries, Multiple|Head Injuries, Closed|Head Trauma,Closed|Head Trauma Injury|Head Trauma, Penetrating|Head Injury, Minor|Head Injury Major|Head Injury, Open|Injuries, Craniocerebral|Injuries, Head|Multiple Head Injury|Trauma, Head
Interventions: DEVICE: InfraScanner 2000™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Internet-delivered Cognitive Behavioral Therapy for Patients With Chronic Pain and Psychiatric Distress
Status: COMPLETED
Conditions: Chronic Pain|Depressive Symptoms|Anxiety|Stress, Psychological
Interventions: BEHAVIORAL: Internet-Delivered Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations
Status: COMPLETED
Conditions: Advanced Ovarian Cancer|Primary Peritoneal Cancer|Advanced Breast Cancer|Advanced Solid Tumors
Interventions: DRUG: BMN 673
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Androgen Blockade Therapy With or Without Zoledronic Acid in Treating Patients With Prostate Cancer and Bone Metastases
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: antiandrogen therapy|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NOTES-Assisted Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Cholecystectomy, Laparoscopic|Endoscopy
Interventions: PROCEDURE: Endoscopically assisted Laparoscopic Cholecystectomy Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind Body Syndrome Therapy for Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain|Chronic Pain Syndrome
Interventions: BEHAVIORAL: Mind Body Intervention 1|BEHAVIORAL: Mind body intervention 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy for Children With Autism Spectrum Disorder and Obsessive Compulsive Behaviour
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Obsessive-Compulsive Behavior
Interventions: BEHAVIORAL: Functional Behavior-Based Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vasodilator Therapy for Heart Failure and Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure|Congestive Heart Failure
Interventions: DRUG: Isosorbide Dinitrate|DRUG: Isosorbide Dinitrate + Hydralazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Therapies for Improving Motor Impairment, Fall-risk and Overall Physical Function
Status: COMPLETED
Conditions: Chronic Stroke|Healthy Aging
Interventions: BEHAVIORAL: Cognitive-motor exergaming|BEHAVIORAL: Conventional balance Training|BEHAVIORAL: Dance Therapy for Stroke|BEHAVIORAL: Dance Therapy for Older adults|BEHAVIORAL: Home education for Older adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-center Study to Evaluate the Efficacy and Safety of Vitamin D3 B.O.N. Intramuscular Injection in Adults With Vitamin D Deficiency
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D3 B.O.N. Injection (cholecalciferol 200,000IU)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mushrooms, Mood and Mental Wellbeing in Gen Z Women
Status: RECRUITING
Conditions: Well-Being, Psychological|Mood|Anxiety|Stress
Interventions: DIETARY_SUPPLEMENT: Lion's mane blend|DIETARY_SUPPLEMENT: Lion's mane and reishi blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Oximetry on Hospitalization in Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: OTHER: True saturation values displayed|OTHER: Altered saturation values displayed.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endothelin Antagonism in ANCA Vasculitis
Status: COMPLETED
Conditions: Vasculitis
Interventions: DRUG: BQ123|DRUG: BQ123/788|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suture Versus Glue (Dermabond) Closure During Cesarean Delivery
Status: UNKNOWN
Conditions: Adhesive; Band|Suture; Complications
Interventions: DEVICE: MODIFIED VICRYL PLUS|DEVICE: DERMABOND GLUE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Recurrent Myelodysplastic Syndrome|Refractory Acute Myeloid Leukemia|Refractory Myelodysplastic Syndrome
Interventions: DRUG: Decitabine|BIOLOGICAL: Pembrolizumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of Ultra Low Doses of Dapagliflozin in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children
Status: RECRUITING
Conditions: Primary Immune Deficiency Disorders|Metabolic Disease
Interventions: BIOLOGICAL: Haploidentical Hematopoietic Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Tissue Regeneration With a Periodontal Dressing
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: periodontal dressing (coe-pak)|PROCEDURE: Guided Tissue Regeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Dimensional Outcomes of Sealing Socket Abutment Combined to Alveolar Ridge Preservation
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-maintainable Posterior Tooth (Molars and Premolars)
Interventions: PROCEDURE: Immediate implantation in posterior region with alveolar ridge preservation combined with sealing socket abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft
Status: COMPLETED
Conditions: Stenosis|Restenosis
Interventions: DEVICE: Covera Vascular Covered Stent following PTA|PROCEDURE: Percutaneous Transluminal Angioplasty (PTA) with Uncoated PTA Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AbioKin - Antibiotic Kinetics
Status: COMPLETED
Conditions: Critical Illness|Infection
Interventions: DRUG: Linezolid|DRUG: Meropenem|DRUG: Piperacillin-tazobactam combination product|DRUG: Vancomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability of DHE Administered by I123 POD Device, IV Injection, and Migranal Nasal Spray in Healthy Adults
Status: COMPLETED
Conditions: Migraine Headache
Interventions: COMBINATION_PRODUCT: INP104|DRUG: Dihydroergotamine Mesylate (DHE)|COMBINATION_PRODUCT: Migranal Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser-excimer Versus High-pressure Dilation to Treat Under-expansion of the Stent
Status: COMPLETED
Conditions: Cardiovascular Diseases|Arterial Disease
Interventions: PROCEDURE: NC ( Non- Compliant) Balloon dilatation|PROCEDURE: Laser Excimer + NC Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saw Palmetto: Symptom Management for Men During Radiation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Saw Palmetto|DRUG: soybean oil soft gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Status: COMPLETED
Conditions: Obesity|Obesity; Endocrine|Insulin Sensitivity|Exercise
Interventions: BEHAVIORAL: Sprint Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Modulations of Allergen-Specific Immunotherapy
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: prednisone, lactose|DRUG: prednisone, colecalciferol, lactose|DRUG: lactose|DRUG: montelukast sodium|DRUG: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair
Status: WITHDRAWN
Conditions: Anesthesia|Stress, Physiological|Surgery
Interventions: PROCEDURE: Adductor Canal Block|DEVICE: Morphine Patient Controlled Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Investigation of the Effects of Different Treatment Techniques on Myofascial Trigger Points in Patients With Temporomandibular Dysfunction (TMD)
Status: COMPLETED
Conditions: Low Level Laser and Occlusal Splint
Interventions: DEVICE: Low Level Laser Therapy|DEVICE: Occlusal Splint Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Montelukast Sodium With Concomitant Administration of Inhaled Budesonide in Asthmatic Patients (0476-075)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK0476; montelukast sodium/Duration of Treatment: 16 weeks|DRUG: Comparator: placebo / Duration of Treatment: 16 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans
Status: COMPLETED
Conditions: Alcohol Consumption|Tobacco Use
Interventions: DRUG: Nicotine|DRUG: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Nicotinamide Riboside in LVAD Recipients
Status: COMPLETED
Conditions: Heart Failure，Congestive|Heart Failure New York Heart Association Class IV|Mitochondrial Alteration
Interventions: DIETARY_SUPPLEMENT: Nicotinamide riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Blocks for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Serratus anterior plane block|PROCEDURE: Erector spinae block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota
Status: RECRUITING
Conditions: Bacterial Vaginoses|Infertility, Female
Interventions: DRUG: Clindamycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Traditional Versus Goal Directed Perioperative Fluid Therapy in High Risk Patients
Status: TERMINATED
Conditions: Postoperative Complications
Interventions: PROCEDURE: Goal directed fluid therapy guided by LiDCOrapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Bone Metastases|High NTX Level
Interventions: DRUG: zometa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Recovery Effect of Bloodletting Puncture at Jing-well Points on Acute Brain Injury Patients
Status: UNKNOWN
Conditions: Traumatic Brain Injury (TBI)
Interventions: OTHER: acupuncture and bloodletting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantification of the Pressure Threshold Related to Tissue Injury in Bedriden Paraplegics
Status: TERMINATED
Conditions: Pressure Ulcer|Bedsore|Spinal Cord Injury|Paraplegia
Interventions: PROCEDURE: Muscle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)
Status: RECRUITING
Conditions: Coronary Artery Disease|Aortic Valve Stenosis|Mitral Valve Insufficiency
Interventions: BEHAVIORAL: PACO intervention for CABG patients|BEHAVIORAL: PACO intervention for AVR patients|BEHAVIORAL: PACO intervention for MVR patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Riocigaut on Migraine Attack Induction in People With Migraine
Status: COMPLETED
Conditions: Migraine Without Aura
Interventions: DRUG: Riociguat (BAY 63-2521)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Responder-derived FMT (R-FMT) and Pembrolizumab in Relapsed/Refractory PD-L1 Positive NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Fecal Microbiota Transplant (FMT)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cladribine Combined With BEAC Pretreatment Regimen in the Treatment of Peripheral T-cell Lymphoma: a Multicenter Clinical Study
Status: RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: BEAC|DRUG: Cladribine combined with BEAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease Including Assessment of Quality of Life (EPPIC-2)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Placebo|DRUG: AST-120
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
Status: COMPLETED
Conditions: Cardiovascular Diseases|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Mixed meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neural Alteration Response to Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Depressed Patients
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: Transcutaneous electrical vagus nerve stimulation|DEVICE: Sham vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of Panitumumab Cisplatin, Fluourouracil and Docetaxel in Locally Advanced or Metastatic Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Omacor® in Taiwanese Hypertriglyceridemic Patients
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Omacor®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intra-articular Injection of Tenoxicam or Meloxicam in TMJ Anterior Disc Displacement With Reduction
Status: RECRUITING
Conditions: Temporomandibular Joint Disc Displacement, With Reduction
Interventions: DRUG: intraarticular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity of Quadrivalent Live Attenuated Influenza Vaccine (LAIV) in Children
Status: COMPLETED
Conditions: Healthy or Stable Chronic Illness
Interventions: BIOLOGICAL: Q/LAIV (MEDI3250)|BIOLOGICAL: FluMist/B/Yamagata|BIOLOGICAL: FluMist/B/Victoria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Perioperative Intravenous Magnesium on Pain After Endoscopic Submucosal Dissection for Gastric Neoplasm: Prospective Randomized Double-blind Placebo Controlled Study
Status: COMPLETED
Conditions: Gastric Neoplasm
Interventions: DRUG: Magnesium Sulfate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cohort Study: Perceptual Urge Sensation
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Osteoporosis
Interventions: OTHER: Micturition diary|OTHER: Hospital Anxiety and Depression scale|OTHER: EuroQol-5D|OTHER: Self-consciousness questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hematopoietic Stem Cell Transplantation Based on Pharmacokinetic and Pharmacodynamic Modeling
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Raltegravir, Tenofovir and Emtricitabine for Peri-exposure Prophylaxis for HIV Infection
Status: UNKNOWN
Conditions: Infection|HIV
Interventions: DRUG: Truvada and Isentress
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of HRS5580 in Prevention of Postoperative Nausea and Vomiting of Adults
Status: NOT_YET_RECRUITING
Conditions: Preventing of Postoperative Nausea and Vomiting in Adults
Interventions: DRUG: HRS5580|DRUG: HRS5580|DRUG: HRS5580|DRUG: Ondansetron|DRUG: blank preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Hydraulic Microprocessor Prosthetic Foot for Traumatic Transtibial Amputees
Status: COMPLETED
Conditions: Unilateral Transtibial Amputee
Interventions: DEVICE: Elan foot prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Benefit of Electrolytic Cleaning on Non-surgical Treatment of Peri-implantitis.
Status: UNKNOWN
Conditions: Peri-Implantitis
Interventions: DEVICE: Implants are decontaminated with electrolytic cleaning|DEVICE: Implants are decontaminated without electrolytic cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Daily Intranasal Oxytocin for Childhood-Onset Schizophrenia
Status: TERMINATED
Conditions: Childhood Onset Psychotic Disorders|Schizophrenia
Interventions: DRUG: Intranasal Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Sedation Strategies for Therapeutic Bronchoscopy
Status: TERMINATED
Conditions: Bronchoscopy|Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil|DEVICE: Laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
Status: COMPLETED
Conditions: Cicatrix|Wound Healing
Interventions: DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Prevascar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica
Status: UNKNOWN
Conditions: Progressive Multiple Sclerosis|Neuromyelitis Optica.
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects and Meaning of a Person-centred and Health-promoting Intervention in Home Care Services
Status: COMPLETED
Conditions: Staff and Older Persons With Home Care Service
Interventions: OTHER: Person-centred and health-promoting home care service|OTHER: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors
Status: RECRUITING
Conditions: Cardiometabolic Health
Interventions: OTHER: air filtration with air purifier with hepa filter|OTHER: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Clinical Study of Evaluation of Recombinant Anti-PD-1 Humanized Monoclonal Antibody Injection (609A) Combined With Doxorubicin Hydrochloride in the Treatment of Metastatic/Unresectable Non-specific Soft Tissue Sarcoma
Status: NOT_YET_RECRUITING
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: 609A|DRUG: doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goat Infant Formula Feeding and Eczema (the GIraFFE Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dermatitis, Atopic|Eczema, Infantile|Infant Development|Child Development
Interventions: DIETARY_SUPPLEMENT: Infant formula and follow-on formula made from whole goat milk|DIETARY_SUPPLEMENT: Infant formula and follow-on formula made from cow's milk ingredients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
Status: COMPLETED
Conditions: Osteoarthritis|Pain Intensity Assessment|Arthralgia|Sciatica|Low Back Pain
Interventions: DRUG: CG 5503;tapentadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study in Attention Deficit Hyperactivity Disorder in Children and Adolescents
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine|DRUG: Osmotic-release oral system methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Medication Adherence Through a Health Literacy-based Intervention for Coronary Heart Disease Patients
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: BEHAVIORAL: Health literacy-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of an Interprofessional Rehabilitation Program for Chronic Low Back Patients in the Ethiopian Health Setting
Status: NOT_YET_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: OTHER: Interprofessional rehabilitation program|OTHER: Usual standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT