pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Different Endoscopic Surgery Procedures in Eosinophilic Chronic Rhinosinusitis With Nasal Polyps
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)|Surgery
Interventions: PROCEDURE: radical endoscopic sinus surgery (RESS) plus Draf 3 surgery.|PROCEDURE: radical endoscopic sinus surgery (RESS)|PROCEDURE: functional endoscopic sinus surgery (FESS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of [68Ga]Ga-NOTA-RG2 PET Imaging in the Diagnosis of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: [68Ga]Ga-NOTA-RG2 PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Application of TachoSil® in Pancreatoduodenectomy
Status: UNKNOWN
Conditions: Pancreatic Neoplasm|Pancreatic Periampullary Cancer|Pancreatic Bordeline Tumor
Interventions: DRUG: Fibrinogen/thrombin-coated collagen patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Video Based Games on Upper Extremity Functions in Mild Mental Retardation Diagnosed Cases
Status: UNKNOWN
Conditions: Mental Retardation|Upper Extremity
Interventions: OTHER: Leap-Motion virtual reality games|OTHER: fine motor skills activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Flavonoids|DRUG: CDobi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Supplemental Oxygen in Patients With IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: OTHER: Medical air|OTHER: Oxygen (2Liter/min)|OTHER: Oxygen (4Liter/min)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?
Status: ACTIVE_NOT_RECRUITING
Conditions: HSIL, High-Grade Squamous Intraepithelial Lesions|Adenocarcinoma in Situ|Early Cervical Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Bioparametric Measures for Correlating Daily Habits and Reducing Blood Pressure
Status: COMPLETED
Conditions: Hypertension|Diet, Mediterranean|Cardiovascular Diseases|Exercise|Machine Learning|Overweight and Obesity|Body Composition|Triglyceride-Storage; Disease
Interventions: BEHAVIORAL: Use of a mobile application based on machine learning with the aim of improving health and body composition parameters.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab-ONYX
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy|Spinal Muscular Atrophy Type 3|Spinal Muscular Atrophy Type II|SMA|Neuromuscular Diseases|Muscular Atrophy|Atrophy|Muscular Atrophy, Spinal|Neuromuscular Manifestations|Anti-myostatin
Interventions: DRUG: Apitegromab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of tDCS on Cortical Plasticity in Healthy Older Adults
Status: WITHDRAWN
Conditions: Healthy Older Adults
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-endodontic Pain After Single-visit Root Canal Treatment
Status: COMPLETED
Conditions: Relate Post-endodontic Pain
Interventions: PROCEDURE: Twisted File Adaptive|PROCEDURE: Balance Force|PROCEDURE: WaveOne|PROCEDURE: Reciproc technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of DKK2 Protein in Cerebral Ischemia-reperfusion Injury
Status: RECRUITING
Conditions: Ischemic Stroke, Acute|Ischemia-reperfusion Injury|Cerebral Edema
Interventions: DIAGNOSTIC_TEST: enzyme-linked immunosorbent assay(ELISA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Cabergoline Tablets and Dostinex Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Cabergoline|DRUG: Dostinex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure
Status: TERMINATED
Conditions: Acute-On-Chronic Liver Failure
Interventions: BIOLOGICAL: allo-APZ2-ACLF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions
Status: RECRUITING
Conditions: Peripheral Artery Disease|Clopidogrel, Poor Metabolism of|Peripheral Vascular Disease|Artery Disease|Peripheral Arterial Occlusive Disease
Interventions: DIAGNOSTIC_TEST: Point of care screening for HPR|DRUG: Ticagrelor 90mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mesenchymal Stem Cell Therapy of Dry Eye Disease in Patients With Sjögren's Syndrome
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca, in Sjogren's Syndrome
Interventions: DRUG: ASCs|DRUG: Cryostor CS10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Vestibular Rehabilitation Significantly Improve the Level of Vestibular Function Following Vestibular Neuritis?
Status: COMPLETED
Conditions: Vestibular Neuritis
Interventions: OTHER: Vestibular rehabilitation|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of New Biomarkers of Banana and Tomato Intake
Status: COMPLETED
Conditions: Biomarkers|Food Intake
Interventions: OTHER: Banana Cavendish|OTHER: Tomato|OTHER: Fresubin ® 2kcal fiber neutral flavor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The AGAINST Protocol: Augmentative Craniotomy in Stroke
Status: NOT_YET_RECRUITING
Conditions: Middle Cerebral Artery Occlusion With Cerebral Infarction
Interventions: PROCEDURE: Augmentative craniotomy|PROCEDURE: Decompressive craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zoptarelin Doxorubicin (AEZS 108) as Second Line Therapy for Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: AEZS-108 / zoptarelin doxorubicin|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine in Acute Leukemia and MDS
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Acute Lymphoblastic Leukemia|Chronic Myeloid Leukemia
Interventions: DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously Untreated Advanced Diffuse Large B-Cell Lymphoma (GATHER)
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: obinutuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: prednisone|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ganglionic Local Opioid Analgesia at the Ganglion Cervicale Superius
Status: COMPLETED
Conditions: Trigeminal Neuralgia, Idiopathic|Postherpetic; Neuralgia, Trigeminal (Etiology)|Glossopharyngeal Neuralgia|Atypical Facial Pain
Interventions: PROCEDURE: MRI after ganglionic local opioid analgesia (GLOA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reducing Hemarthrosis in ACL Reconstruction With BTB Autograft by the Administration of Intravenous TXA
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Nedaplatin|RADIATION: chest radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Vancomycin for Secondary Prophylaxis of Clostridium Difficile Infection (CDI)
Status: TERMINATED
Conditions: Clostridium Difficile Infection|Clostridium Difficile Infection Recurrence
Interventions: DRUG: Oral Vancomycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19, Long Haul
Interventions: DRUG: Ritonavir-Boosted Nirmatrelvir (Paxlovid)|DIAGNOSTIC_TEST: Physiological Evaluation|BIOLOGICAL: Moderna COVID-19 Vaccine|BEHAVIORAL: Biopsychological|BEHAVIORAL: Behavioral (e.g., Psychotherapy, Lifestyle Counseling)|GENETIC: Genetic (including gene transfer, stem cell and recombinant DNA)|COMBINATION_PRODUCT: Multidisciplinary approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TREATMENT WITH ANTI-SARS-COV-2 IMMUNOGLOBULIN IN PATIENTS WITH COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Anti-SARS-CoV-2 immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone for Cerebral Toxoplasmosis
Status: RECRUITING
Conditions: Toxoplasmosis, Cerebral
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reflux Band in Laryngopharyngeal Reflux
Status: RECRUITING
Conditions: Laryngopharyngeal Reflux
Interventions: DEVICE: External Upper Esophageal Sphincter (UES) Compression Device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Performance of an Intradermal Injection Treatment for Face Photoaging: Interstitial or Cushion Technique in Comparison to Bolus Technique at Five Points (Half - Face Method Within Subjects)
Status: COMPLETED
Conditions: Face Photoaging
Interventions: DEVICE: SUNEKOS ® 200|DEVICE: "SUNEKOS® 1200" and "SUNEKOS® 200"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Full-thickness Gastroplication With the GERD-X System on Atypical Gastro-esophageal-reflux-symptoms
Status: UNKNOWN
Conditions: Atypical Gastroesophageal Reflux Symptoms|Objectified Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Full-thickness gastroplication (GERD-X)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)
Status: UNKNOWN
Conditions: GVHD,Acute|GVHD, Chronic
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PF-06741086 Multiple Dose Study in Severe Hemophilia
Status: COMPLETED
Conditions: Hemophilia A or B
Interventions: BIOLOGICAL: PF-06741086|BIOLOGICAL: PF-06741086|BIOLOGICAL: PF-06741086|BIOLOGICAL: PF-06741086
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Milk Warming on the Very Low Birth Weight Infant
Status: COMPLETED
Conditions: Very Low Birth Weight Infant|Weight Gain|Feeding Disorder Neonatal
Interventions: OTHER: Treatment Guardian Milk Warmer (Medela TM)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine patch|OTHER: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Next-Day Residual Effects of Tasimelteon Compared With Placebo and Active Control in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tasimelteon|DRUG: Active Control Placebo|DRUG: Tasimelteon Placebo|DRUG: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bevacizumab Biosimilar Plus FOLFOX4 in the Treatment of Recurrent HCC After Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Post-orthotopic Liver Transplantation|Hepatocellular Carcinoma Recurrent
Interventions: DRUG: Bevacizumab Biosimilar IBI305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
Status: COMPLETED
Conditions: Symptomatic Contact Lens Wearers
Interventions: DEVICE: FID 114675A Multi-Purpose Disinfecting Solution (MPDS)|DEVICE: renu fresh Multi-Purpose Solution (MPS)|DEVICE: Contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carbetocin Versus Oxytocin in the Management of Atonic Post Partum Haemorrhage (PPH) in Women Delivered Vaginally: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Obstetrics
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physiotherapy in Individuals With Persistent Symptoms Following Concussion
Status: COMPLETED
Conditions: Sport-related Concussion
Interventions: OTHER: Control postural education, general range of motion and strengthening in addition to the standard of care|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effects of Platelet-Rich Plasma on Postoperative Complications After Meningomyelocele
Status: COMPLETED
Conditions: Meningomyelocele/Spina Bifida
Interventions: PROCEDURE: Use of Platelet-Rich Plasma after meningomyelocele sac repair|PROCEDURE: meningomyelocele sac repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Testosterone in Improving Libido in Postmenopausal Female Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Sexual Dysfunction|Sexuality and Reproductive Issues|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: therapeutic testosterone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Vaping Prevention Advertisements
Status: COMPLETED
Conditions: Vaping
Interventions: BEHAVIORAL: The FDA's The REal Cost vaping prevention ads - Health harms theme|BEHAVIORAL: The FDA's The Real Cost vaping prevention ads - Addiction theme|BEHAVIORAL: Neutral vaping ads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Late Incomplete Stent Apposition Evaluation II: Comparison Between Polimer-based and No-polimer Stent System. IVUS Based Study
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous transluminal Coronary Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iPACK Block With Dexamethasone For Total Knee Replacement
Status: TERMINATED
Conditions: Knee Osteoarthritis|Acute Pain|Anesthesia, Local|Regional Anesthesia
Interventions: DRUG: ropivacaine 0.25% with epinephrine and 6mg dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML
Status: RECRUITING
Conditions: AML, Adult
Interventions: DRUG: BST-236|DRUG: venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fe Absorption in Mother and Child Pairs From Wheat Fortified With Iron With and Without Phenolic Containing Beverages
Status: COMPLETED
Conditions: Anemia; Deficiency, Nutritional, With Poor Iron Absorption
Interventions: OTHER: Ferrous sulfate fortified bread with tea|OTHER: ferrous sulfate fortified bread with water|OTHER: Ferrous fumarate fortified bread with tea|OTHER: Ferrous fumarate fortified bread with water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity
Status: NOT_YET_RECRUITING
Conditions: Insulin Resistance|Abdominal Obesity|Diabetes
Interventions: OTHER: High intensity interval exercise|OTHER: Focused ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anti-FcRL5 CAR-T Cell Therapy in Treating Relapsed and Refractory Multiple Myeloma (R/R MM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: anti-FcRL5 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Transplantation in the Treatment of Chronic Antibody Mediated Kidney Graft Rejection (ABMR)
Status: TERMINATED
Conditions: Interventional
Interventions: OTHER: MSC transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-CDOP Regimen in the Treatment of Newly Diagnosed Non-Hodgkin's Lymphoma With High Tumor Burden
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Follicular Lymphoma Grade 3B
Interventions: COMBINATION_PRODUCT: R-CDOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PGL4001 Versus Placebo in Uterine Myomas
Status: COMPLETED
Conditions: Uterine Myomas
Interventions: DRUG: PGL4001 (ulipristal) and iron|DRUG: PGL4001 matching placebo and iron|DRUG: PGL4001 (ulipristal) and iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Spine Manipulation Versus Pharmacological Therapy in Young Women With Primary Dysmenorrhea
Status: COMPLETED
Conditions: Women With Primary Dysmenorrhea
Interventions: OTHER: Lumbar spine manipulation|DRUG: Hyoscine and Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Distal Movement of Maxillary Dentition With Zygomatic Miniplates Using Cone Beam Computed Tomography
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: DEVICE: Class II correction using miniplates in zygomatic region
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bi-level ESPB Application in Patients Undergoing VATS
Status: COMPLETED
Conditions: Pain, Postoperative|Thoracic Surgery, Video-Assisted|Erector Spinae Plane Block|Multimodal Analgesia
Interventions: PROCEDURE: One-level Erector Spinae Plane Block|PROCEDURE: Bi-level Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MINDFUL-PC for Portuguese Speakers Pilot Study 2020
Status: TERMINATED
Conditions: Depression|Anxiety Disorders|Stress Related Disorder|Adjustment Disorders|Chronic Illness
Interventions: BEHAVIORAL: Mindfulness Training for Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy Evaluation of the BD FACS Presto System
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome
Interventions: DEVICE: Investigational BD FACSPresto System|DEVICE: BD FACSCalibur flow cytometer|DEVICE: Sysmex hematology analyzer KX-21
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Solifenacin Succinate With Tamsulosin HCl in Males With Lower Urinary Tract Symptoms and Bladder Outlet Obstruction
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Bladder Outlet Obstruction
Interventions: DRUG: solifenacin succinate|DRUG: tamsulosin hydrochloride|DRUG: Placebo to solifenacin|DRUG: Placebo to tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Hepatitis With Sofosbuvir in Combination With Ribavirin With or Without Pegylated Interferon: North India Gastroenterology Consortium
Status: COMPLETED
Conditions: Hepatitis, Chronic
Interventions: DRUG: Sofosbuvir, Ribavirin, With or Without Pegylated Interferon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dietary Protein Sources and Atherogenic Dyslipidemia
Status: COMPLETED
Conditions: Cardiovascular Disease|Dyslipidemia|Insulin Resistance|Inflammation
Interventions: OTHER: High saturated fat red meat diet|OTHER: High saturated fat non-meat diet|OTHER: High saturated fat white meat diet|OTHER: Low saturated fat red meat diet|OTHER: Low saturated fat white meat diet|OTHER: Low saturated fat non meat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tele-nursing Practices Based on Technological Competence Theory in Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: OTHER: tele nursing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Play2Sleep: Using Play to Improve Infant Sleep
Status: COMPLETED
Conditions: Disturbances in Initiating and Maintaining Sleep|Parent-Child Relations
Interventions: BEHAVIORAL: Play2Sleep|BEHAVIORAL: Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bowel Preparation Before 3D Rectal Water Contrast Transvaginal Ultrasonography for Rectosigmoid Endometriosis
Status: COMPLETED
Conditions: Endometriosis, Rectum
Interventions: PROCEDURE: 3D-RWC-TVS with bowel preparation|PROCEDURE: 3D-RWC-TVS without bowel preparation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Tamiflu (Oseltamivir) for Seasonal Prophylaxis of Influenza in Children.
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: oseltamivir [Tamiflu]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training
Status: COMPLETED
Conditions: Congenital Heart Disease|Single Ventricle|Univentricular Heart
Interventions: OTHER: Aerobic Exercise Training|OTHER: Inspiratory Muscle Training|OTHER: No Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Prevent Mental Health Disorders of Women and Their Partners Who Experienced Pregnancy Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Stillbirth and Fetal Death
Interventions: OTHER: GUIA ATENCION MULTIDISCIPLINAR SANT BOI|OTHER: USUAL CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two NN5401 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec/insulin aspart|DRUG: insulin glargine|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life of Colorectal Cancer Screenees in the Period Between Colonoscopy and Next Clinic Visit for Final Report: Does Real-time Endoscopic Optical Diagnosis Improve Their Quality of Life
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Colonoscopy|Quality of Life|Mass Screening|Anxiety
Interventions: OTHER: Real-time colonoscopic optical diagnosis for colorectal neoplasm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF
Status: COMPLETED
Conditions: Obesity|Heart Failure With Normal Ejection Fraction
Interventions: BEHAVIORAL: UFA dietary recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BMS-986484|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Trial Using Artificial Intelligence(AI) Diet Application for Management of Diet in Diabetes Patients
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DEVICE: CGMS|BEHAVIORAL: AI diet application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avalglucosidase Alfa French Post-trial Access for Participants With Pompe Disease (PTA Avalglucosidase)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glycogen Storage Disease Type II
Interventions: DRUG: Avalglucosidase alfa (GZ402666)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue and Clinical Characterisation of Temporomandibular Joint Diseases
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Temporomandibular Arthritis|Temporomandibular Joint Disc Displacement|Temporomandibular Joint Osteoarthritis
Interventions: PROCEDURE: Arthroscopy or discectomy with sampling of synovial fluid and synovial tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III Study of DA-3031(PEG-G-CSF) in Chemotherapy-induced Neutropenia
Status: COMPLETED
Conditions: Chemotherapy Induced Neutropenia
Interventions: DRUG: PEG-G-CSF|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Lifestyle Intervention to Improve in Vitro Fertilization Results
Status: UNKNOWN
Conditions: Sterility|Placenta; Implantation|Risk Reduction Behavior|Lifestyle|Neonatal Hypoglycemia
Interventions: BEHAVIORAL: Daily walking|BEHAVIORAL: Dietary recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Laparoscopic Operation on Rocuronium and Cisatracurium: Pharmacokinetic and Pharmacodynamic Analysis
Status: COMPLETED
Conditions: C.Delivery; Surgery (Previous), Gynecological
Interventions: DRUG: rocuronium|DRUG: cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Remimazolam on Motor Evoked Potential
Status: COMPLETED
Conditions: Spine Disease
Interventions: DRUG: Propofol|DRUG: Remimazolam Besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study
Status: COMPLETED
Conditions: Meningitis, Tuberculous|Pharmacokinetics|Pharmacodynamics|Tolerability
Interventions: DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Education, Motivational Interviewing and Exercise in Chronic Neck Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Neck Pain
Interventions: OTHER: COGMO Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: Esomeprazole 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Double Blind Randomised Study of Lapatinib and Placebo in Metastatic TCC of the Urothelium
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: lapatinib ditosylate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay
Status: COMPLETED
Conditions: Treatment Resistant Depression|Generalized Anxiety Disorder
Interventions: DEVICE: Genecept Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage
Status: RECRUITING
Conditions: Postpartum Hemorrhage|Immediate Postpartum Hemorrhage|Hemorrhage, Postpartum
Interventions: DEVICE: KOKO Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Interpersonal and Social Rhythm Therapy for Adolescents (IPSRT-A)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Partnered Approach to Prevent Diabetes
Status: COMPLETED
Conditions: Pre-diabetic State|Overweight|Obesity
Interventions: BEHAVIORAL: Clinical referral to diabetes prevention lifestyle|BEHAVIORAL: Clinical referral to group diabetes prevention lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HAIC Combined With Durvalumab, Tremelimumab and Bevacizumab as Conversion Therapy for Potentially Resectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Unrescetable Hepatocellular Carcinoma
Interventions: DRUG: HAIC+Durvalumab+Tremelimumab+Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lubiprostone for the Treatment of Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Lubiprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EL625 in Persistent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Small Lymphocytic|Leukemia, Lymphocytic, Chronic
Interventions: DRUG: cenersen sodium|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Phantom Limb Pain After Transtibial Amputation
Status: TERMINATED
Conditions: Phantom Limb Pain|Chronic Pain|Prevention
Interventions: PROCEDURE: Sciatic name block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Functional and Cognitive Impairment in Hospitalized Oncogeriatric Patients
Status: UNKNOWN
Conditions: Cancer|Hospital Acquired Condition|Debility|Aging
Interventions: BEHAVIORAL: Multicomponent exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Dose Escalation Study of BAY 1841788 in Japanese Metastatic Castration-resistant Prostate Cancer (mCRPC) Subjects
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: BAY 1841788(ODM-201)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Locoregional Treatment of Initially Biopsy-proven Node-positive Breast Cancer After Primary Systemic Therapy
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Omission of axillary lymph node dissection|RADIATION: Omission of regional irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction
Status: RECRUITING
Conditions: Early PCSK9 Inhibitor on Ventricular Remodling
Interventions: DRUG: PCSK9 inhibitor （Alirocumab）plus standard medications|DRUG: standard medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Niraparib + Dostarlimab In BRCA Mutated Breast Cancer
Status: RECRUITING
Conditions: Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer|Breast Cancer|HER2-negative Breast Cancer|Germline BRCA1 Gene Mutation|Germline BRCA2 Gene Mutation|Deleterious PALB2 Gene Mutation
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Distraction for Reduction
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DEVICE: Placebo comparator: VR googles and the non reality experience|DEVICE: Active Comparator: VR googles and the real VR program to enter act with and experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques
Status: RECRUITING
Conditions: Stroke, Ischemic|Atherosclerosis, Cerebral
Interventions: DRUG: Atorvastatin Calcium|DRUG: Atorvastatin Calcium|DRUG: Probucol|DRUG: PCSK9 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Iodine 131 Anti B1 Antibody for 1st or 2nd Relapsed Indolent B-Cell Lymphomas or B-Cell Lymphomas That Have Transformed to a More Aggressive Histology
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: tositumomab and Iodine I 131 tositumomab (anti-B1 antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of HMG-CoA Reductase Inhibition (Atorvastatin)on Renal Hemodynamics, Tubular Function and Vasoactive Hormones on Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HMG-CoA reductase inhibition (atorvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: The Use of Home Oral Glucose Tolerance Test Kit in Screening Cystic Fibrosis Related Diabetes
Status: UNKNOWN
Conditions: Cystic Fibrosis Related Diabetes|Cystic Fibrosis
Interventions: DEVICE: Home Oral Glucose Tolerance Test kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: ROBot Assisted Physical Training of Older Patients During acUte hospitaliSaTion
Status: RECRUITING
Conditions: Functional Decline|ADL|Physical Inactivity|Acute Illness
Interventions: OTHER: Active Robot assisted physical training during acute hospitalisation|OTHER: Passive Robot assisted physical training during acute hospitalisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases
Status: UNKNOWN
Conditions: Psoriasis|Cutaneous T Cell Lymphoma|Lymphoproliferative Disorders|Eczema|Lichen Planus|Prurigo|Pruritus|Polymorphic Light Eruption|Graft Vs Host Disease|Mastocytosis|Vitiligo
Interventions: OTHER: Photo(chemo)therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Home-based Gait Rehabilitation Service Using Instrumented Insole
Status: RECRUITING
Conditions: Gait Disorders, Neurologic
Interventions: DEVICE: Monitoring system using a insole-type gait analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The American Glaucoma Society (AGS) Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS)
Status: TERMINATED
Conditions: Glaucoma
Interventions: DEVICE: Baerveldt Glaucoma Implant 350-mm2 / BG101-350|PROCEDURE: Transscleral Diode Laser Cyclophotocoagulation|DEVICE: Ahmed Model FP7 Flexible Plate|DEVICE: Baerveldt Glaucoma Implant 250-mm2 / BG103-250
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients
Status: NOT_YET_RECRUITING
Conditions: Effect of Drug
Interventions: DRUG: Fentanyl|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Primary Angioplasty for STEMI During COVID-19 Pandemic (ISACS-STEMI COVID-19) Registry
Status: UNKNOWN
Conditions: ST Elevated Myocardial Infarction Undergoing Mechanical Reperfusion
Interventions: DEVICE: Percutaneous Coronary Revascularization for STEMI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: PAC-1 Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Panzem Nanocrystal Colloidal Dispersion (NCD) in Combination With Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: Panzem NCD|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: DRUG: allopurinol|DRUG: glucantime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technological and Patient-tailored Innovations for Maximizing Effectiveness of Cardiac Arrest Resuscitation
Status: NOT_YET_RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Cardiac Arrest
Interventions: DEVICE: Wearable device|OTHER: Cardiopulmonary resuscitation|OTHER: CT scan, TEE exam, or chest X ray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: CMF regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|DRUG: tamoxifen citrate|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation and Steroid Versus Steroid Alone for Relief of Pain in Patients With Advanced Knee and Hip Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: PROCEDURE: Radiofrequency Ablation (RFA)|PROCEDURE: Perineural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine 10 mg/day|DRUG: Vortioxetine 20 mg/day|DRUG: Fluoxetine 20mg/day|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hallux Valgus Manual Therapy Based on Global Postural Reeducation.
Status: COMPLETED
Conditions: Hallux Valgus|Hallux Deformity|Foot Deformities
Interventions: OTHER: Global postural reeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjustable Continence Therapy (ACT) Device for the Treatment of Female Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: ACT (Adjustable Continence Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Maternal Post-partum Pain With Suppositories
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Belladonna and opioid suppository|DRUG: Glycerin Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Stroke Rehabilitation With Contralesional Brain-Computer Interface
Status: TERMINATED
Conditions: Chronic Stroke|Hemiparesis
Interventions: DEVICE: BCI Rehabilitation|OTHER: Range of Motion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE