pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: RESIST-2: 2nd-line ART for HIV-2 Infection
Status: TERMINATED
Conditions: HIV-2 Infection
Interventions: DIAGNOSTIC_TEST: HIV-2 Genotypic Drug Resistance Testing using DBS|DRUG: 2nd line ART ( Zidovudine 300mg BID + Lamivudine 150mg BID or Tenofovir DF 300mg QD + Lamividine 300mg QD or Emtricitabine 200mg QD + Lopinavir/Ritonavir 400/100mg BID)|DRUG: 2nd line ART (Tenofovir DF 300mg QD + Lamividine 300mg QD or Emtricitabine 200mg QD + Lopinavir/Ritonavir 400/100mg BID + Raltegravir 400mg BID )|DRUG: 2nd line ART (Tenofovir DF 300mg QD + Lamividine 300mg QD or Tenofovir DF 300mg QD + Emtricitabine 200mg QD + Darunavir 600mg BID-Ritonavir 100mg BID +Raltegravir 400mg BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Liposarcoma
Status: COMPLETED
Conditions: Liposarcoma|Surgically Unresectable Liposarcoma|Metastatic Liposarcoma
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect Of Instrumental-Assisted Soft Tissue Mobilization Technique on Physical Fitness Parameters
Status: COMPLETED
Conditions: Physical Fitness
Interventions: OTHER: INSTRUMENTAL-ASSISTED SOFT TISSUE MOBILIZATION TECHNIQUE|OTHER: NO INTERVENTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced Headache
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Cilostazol 200mg|DRUG: SUMAtriptan 6 MG/ML|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Her2/Neu Expression in Gastric Cancer With Dual or Multiple Tumor Tissue Paraffin Blocks
Status: UNKNOWN
Conditions: Gastric Cancer|HER-2
Interventions: OTHER: Dual or Multiple Paraffin Blocks|OTHER: One Paraffin Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Difference Between Interval and Continous Intradialytic Exercise on Functional Capacity in Hemodialysis Patient
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: OTHER: Aerobic pedaling exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 1000 Hertz (Hz), Burst, and Standard Spinal Cord Stimulation in Chronic Pain Relief
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DEVICE: Spinal cord stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: VR-based Intervention for Cognitive Restoration
Status: RECRUITING
Conditions: Breast Cancer|Cognitive Dysfunction|Virtual Reality
Interventions: BEHAVIORAL: Virtual reality-based cognitive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite
Status: WITHDRAWN
Conditions: Anorexia
Interventions: DRUG: Megestrol Acetate|DRUG: Mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SBRT and Anti-programmed Cell Death Protein 1(Anti-PD-1) in Late Stage or Recurrent Pancreatic Cancer Patients
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: RADIATION: SBRT|DRUG: anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymosin Alpha-1 in Combination With Peg-Interferon Alfa- 2a and Ribavirin for the Therapy of Chronic Hepatitis C Nonresponsive to the Combination of IFN and Ribavirin.
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: BIOLOGICAL: Thymosin alpha 1|DRUG: Ribavirin|BIOLOGICAL: PEGinterferon alfa2a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone
Status: TERMINATED
Conditions: Breast Cancer|Hypercalcemia of Malignancy|Metastatic Cancer|Musculoskeletal Complications|Pain
Interventions: DRUG: zoledronic acid|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIA
Status: COMPLETED
Conditions: Bladder Dysfunction
Interventions: DRUG: bethanechol chloride|DEVICE: early bladder training|OTHER: early bladder training and bethanechol chloride|OTHER: no early bladder training and no bethanechol chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biological Dating of Cerebral Ischemia With GST-π/PRDX1 to Detect Patients With Stroke of Unknown Onset Within the Therapeutic Window of Thrombolysis
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: Blood Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breast Cancer Trial of RPR109881 Versus Capecitabine in Male or Female Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastases
Interventions: DRUG: larotaxel (RPR109881, XRP9881)|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon Alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: recombinant interferon alfa|PROCEDURE: lymphangiography|DRUG: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pulsatile Pressure Waveform to Confirm Correct Placement of the Epidural in Laboring Patients
Status: TERMINATED
Conditions: Analgesia, Epidural
Interventions: PROCEDURE: Epidural Pressure Waveform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/II Open Label Study To Evaluate the Antiviral Potential of Combination Low-Dose Therapy With Zidovudine and Interferon-Alpha 2A in Patients With Symptomatic HIV Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interferon alfa-2a|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone (DHEA) Treatment in Women and Men Experiencing Hypoactive Sexual Desire Disorder
Status: UNKNOWN
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Dehydroepiandrosterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients
Status: UNKNOWN
Conditions: HBV Coinfection|HIV Infections
Interventions: DRUG: raltegravir and tenofovir and lamivudine|DRUG: efavirenz+tenofovir+lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collision Warning Device for Blind and Visually Impaired
Status: COMPLETED
Conditions: Hemianopia|Hemianopsia|Peripheral Visual Field Defect|Blindness|Retinitis Pigmentosa|Glaucoma
Interventions: DEVICE: Collision warning device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Marine Protein Hydrolysate as Dietary Supplement in Elderly Part I
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Marine protein hydrolysate (mph)|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Kidney Cancer|Renal Carcinoma|Kidney Cancer Metastatic
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Radiotherapy Plus Niraparib and Toripalimab in Patients With Recurrent Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Recurrent Small Cell Lung Cancer
Interventions: RADIATION: SBRT|DRUG: Toripalimab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEP With 68-DOTANOC in Gastroenteropancreatic Neuroendocrine Tumors
Status: COMPLETED
Conditions: Patients With Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: 68-Ga-DOTANOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.
Status: COMPLETED
Conditions: Parkinson Disease|Parkinson
Interventions: OTHER: Computer game based balance and walking rehabilitation for individuals with Parkinson's Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Laparoscopic Cholecystectomy Following ERCP in Concomitant Gallstones and Common Bile Duct Stones
Status: COMPLETED
Conditions: Choledocholithiasis With Cholecystitis
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Computer-Guided Secondary Alveolar Cleft Bone Grafting With and Without Platelet-Rich Fibrin
Status: COMPLETED
Conditions: Alveolar Bone Grafting
Interventions: PROCEDURE: Platelet-rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
Status: RECRUITING
Conditions: Cancer Risk|Cancer Predisposition Syndrome|Hereditary Cancer Prediction|Childhood Cancer Survivors|Adult Cancer Survivors|IARC Carcinogens|Smoking History|Lung Cancer|Ductal/Lobular Carcinoma|Barrett Esophagus|Pancreatic Precursor Lesions|Colonic Dysplasia/Adenomata|Non-Alcoholic Fatty Liver Disease|Non Alcoholic Steatohepatitis|Cirrhosis|High Grade Prostatic Epithelial Neoplasia|High-grade Bladder Urothelial Dysplasia/Carcinoma in Situ|Adenomatous Hyperplasia|High-risk Oral Precancerous Diseases|Melanocytic Lesion, Adult|Hematologic Malignancy|Lung; Node|Serous Tubal Intraepithelial Carcinoma|Endometrial Intraepithelial Neoplasia|Cervical and Endocervical Carcinoma in Situ|Vulvar Intraepithelial Neoplasia|Nephrogenic Rests|Benign Bone Lesions With Risk of Malignant Degeneration|Giant Cell Tumor|Osteochondroma|Spitz Nevus
Interventions: OTHER: Samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Light, Metabolic Syndrome and Alzheimer's Disease - Aim 2
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Type2 Diabetes
Interventions: DEVICE: Tailored Lighting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Real Time Evaluation of Dynamic Changes of the Lungs During Respiratory Support of VLBW Neonates Using EIT
Status: RECRUITING
Conditions: RDS - Infants|RDS of Prematurity|Respiratory Failure|Prematurity|Very Low Birth Weight Infant
Interventions: DEVICE: Lung electrical impedance tomography monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Endoscope Water Pump Flow Rates on Successful Unsedated Colonoscopy by Water Immersion Method: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Effect of Endoscope Water Pump Flow Rates
Interventions: PROCEDURE: higher flow rates|PROCEDURE: lower flow rates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Collaborative Health Management Model on Heart Failure Patient
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: BEHAVIORAL: collaborative health management model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Leukemia|Leukemia, Myeloid|Leukemia, Myeloid, Acute|Preleukemia|Myelodysplastic Syndromes|Refractory Acute Myeloid Leukemia
Interventions: DRUG: BH-30236
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colloid Preload Versus Colloid Coload During Cesarean Deliveries
Status: UNKNOWN
Conditions: Anesthesia; Adverse Effect, Spinal and Epidural|Hypotension
Interventions: DRUG: hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®)|DRUG: hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy of Panax Ginseng on Lipid Metabolism in Men and the Relationship With Sports Practice.
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: DIETARY_SUPPLEMENT: Panax Ginseng Supplementation|DIETARY_SUPPLEMENT: Placebo Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure Therapy for Auditory Sensitivity in Autism
Status: COMPLETED
Conditions: Sensory Disorders|Autism|Autism Spectrum Disorder|Autism With High Cognitive Abilities|Autistic Behavior|Hyperacusis
Interventions: BEHAVIORAL: Exposure therapy|BEHAVIORAL: Psycho-education|BEHAVIORAL: Caregiver education/home program development
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Two Internet-based Self-help Interventions for Loneliness.
Status: COMPLETED
Conditions: Loneliness
Interventions: OTHER: SOLUS-D + weekly feedback by a coach|OTHER: SOLUS-D + weekly automated messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium (ca),Phosphorus( P) and 25-hydroxyvitamin D(25OHD)] in Infants Born ≤ 32 PMA Gestational Weeks (GA)
Status: UNKNOWN
Conditions: Infant, Premature, Diseases
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol 400|DIETARY_SUPPLEMENT: Cholecalciferol 800|DRUG: Cholecalciferol 1200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment
Status: UNKNOWN
Conditions: Dentin Sensitivity|Hypersensitivity Dentin|Dentine Hypersensitivity|Dentin Hypersensitivity
Interventions: DRUG: Potassium Oxalate 5%|DRUG: Potassium Oxalate 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Extensive Abdominal Lavage on Postoperative Inflammation Following Full Thickness Excision of Deep Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: PROCEDURE: Extensive abdominal lavage|PROCEDURE: Rinsing of the abdomen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Oral Micronized Progesterone in the Prevention of Spontaneous Preterm Birth
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: DRUG: micronized progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Metoprolol Succinate Extended Release Tablets 200 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Metoprolol Succinate ER Tablet 200 mg|DRUG: 'TOPROL-XL®' ER Tablets 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STAD-1 Small Cell Lung Cancer Toxicity Adjusted Dosing Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: cisplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Propofol|DRUG: Methohexital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome
Status: COMPLETED
Conditions: Albinism|Inborn Errors of Metabolism|Oculocutaneous Albinism|Platelet Storage Pool Deficiency|Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Sulphadoxine-pyrimethamine|DRUG: Sulphadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention Program to Address PTSD in People Living With HIV
Status: COMPLETED
Conditions: HIV|AIDS|Mindfulness-based Stress Reduction|China|Resilience|PTSD
Interventions: BEHAVIORAL: Trauma Resiliency Mindfulness-Informed Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nutritional and Contractile Regulation of Muscle Growth
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: Rapamycin|OTHER: Amino acid supplementation|OTHER: Low-intensity resistance exercise|DRUG: Sodium nitroprusside|DEVICE: Blood flow restriction cuff|OTHER: Low-intensity resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Development, Safety, and Feasibility of an Artificial Intelligence-Powered Platform (NodeAI) for Real-Time Prediction of Mediastinal Lymph Node Malignancy During Endobronchial Ultrasound Staging for Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Non Small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: NodeAI|DIAGNOSTIC_TEST: Surgeon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recombinant Human Mannose-Binding Lectin (MBL) in Treating Young Patients With MBL Deficiency and Fever and Neutropenia
Status: WITHDRAWN
Conditions: Fever, Sweats, and Hot Flashes|Infection|Leukemia|Lymphoma|Myelodysplastic Syndromes|Neutropenia|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: recombinant human mannose-binding lectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in Epilepsy
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Retigabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Brief Motivational Interviewing on Periodontal Clinical Outcomes: a 3-year Post-trial Follow-up
Status: COMPLETED
Conditions: Periodontal Diseases|Plaque Score|Bleeding on Probing|Gingival Index
Interventions: OTHER: BMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An AI-based mHealth Intervention to Improve HIV Testing
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: An AI-chatbot-based mHealth intervention|BEHAVIORAL: An attention-chatbot-based mHealth intervention|BEHAVIORAL: Educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric Patients
Status: TERMINATED
Conditions: Pharyngitis|Tonsillitis
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromyographic Evaluation of the Efficacy of Manual Therapy in Temporomandibular Joint Dysfunction.
Status: COMPLETED
Conditions: Temporomandibular Joint Dysfunction
Interventions: OTHER: Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Oral Beclomethasone Dipropionate With Ten Days of Prednisone for Treatment of Gastrointestinal GVHD
Status: COMPLETED
Conditions: Graft Vs Host Disease|Gastrointestinal Graft-Versus-Host Disease
Interventions: DRUG: Oral beclomethasone dipropionate (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Improving Working Memory in Older Adults
Status: RECRUITING
Conditions: Large-scale Physiological Foundations of Memory Decline in Aging Humans
Interventions: DEVICE: High definition transcranial electrical current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn's Disease|Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Digital Mind Body Intervention mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Relationship Between Gut Microbiome, Probiotics, and Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DIETARY_SUPPLEMENT: PS23 live|DIETARY_SUPPLEMENT: PS23 heat-treated|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER)
Status: COMPLETED
Conditions: Febrile Neutropenia|Stage 0 Breast Cancer|Stage 0 Colorectal Cancer|Stage 0 Non-Small Cell Lung Cancer|Stage I Colorectal Cancer|Stage IA Breast Cancer|Stage IA Non-Small Cell Lung Carcinoma|Stage IB Breast Cancer|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Breast Cancer|Stage IIA Colorectal Cancer|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Breast Cancer|Stage IIB Colorectal Cancer|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIC Colorectal Cancer|Stage IIIA Breast Cancer|Stage IIIA Colorectal Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Breast Cancer|Stage IIIB Colorectal Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IIIC Breast Cancer|Stage IIIC Colorectal Cancer|Stage IV Breast Cancer|Stage IV Non-Small Cell Lung Cancer|Stage IVA Colorectal Cancer|Stage IVB Colorectal Cancer
Interventions: OTHER: Preventive Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Video Assisted Thoracoscopic Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine Hcl 0.25% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of Different Formulations of Risedronate in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: risedronate DR (Phase III clinical supply)|DRUG: risedronate 35 mg DR (Commercial Tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|BIOLOGICAL: Obinutuzumab|OTHER: Questionnaire Administration|BIOLOGICAL: Tafasitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Botulinum Toxin Injection at Hip Adductor Muscles in Patients With Spastic Cerebral Palsy, Pilot Study
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: medication Botulinum A injection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Outcome of Pediatric Fracture of Neck Femur Fixation by Plate and Screws
Status: RECRUITING
Conditions: Fracture of Pediatric Neck Femur
Interventions: PROCEDURE: fixation by plate and screws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?
Status: COMPLETED
Conditions: Ventral Hernia|Umbilical Hernia|Incisional Hernia|Postoperative Complications|Pain, Postoperative
Interventions: DRUG: Transabdominal Plane Block|DRUG: Non Transabdominal Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Warm Water Footbath Intervention on Sleep Quality , Fatigue and Heart Rate Variability in Patients With Heart Failure
Status: ENROLLING_BY_INVITATION
Conditions: Footbath|Heart Failure|Sleep Quality|Fatigue|Heart Rate Variability
Interventions: OTHER: footbath and actigraphy|DEVICE: actigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018
Status: COMPLETED
Conditions: Refractory Cardiac Arrest|ExtraCorporeal Membrane Oxygenation (ECMO)
Interventions: OTHER: SF36 questionnaire via telephone interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic Lesions
Status: COMPLETED
Conditions: Pancreatic Cystic Lesion
Interventions: DRUG: Placebo|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of External Heat on a Transdermal Granisetron Patch in Pharmacokinetics (PK) of Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: granisetron IV|DRUG: granisetron patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MenB Vaccine: Implementation Via Information, Empowerment and Accessibility
Status: COMPLETED
Conditions: Meningococcal Vaccine
Interventions: OTHER: Awareness|OTHER: Education|OTHER: Empowerment|OTHER: Accessibility
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Right Ventricular (RV) Pacing in Early Post-operative Continuous Flow Left Ventricular Assist Device (LVAD)
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)|DEVICE: Implantable Cardioverter-Defibrillator (subject's pre-existing ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Postprandial Lipids in IBS and Nutritional Treatment
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: turmeric|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ipilimumab in Patients With Advanced Melanoma and Spontaneous Preexisting Immune Response to NY-ESO-1
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Median Effective Dose of Rocuronium for the Prevention of Myofibrillation Caused by the Injection of Succinylcholine
Status: COMPLETED
Conditions: Succinylcholine|Myofibrillation
Interventions: DRUG: rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Delayed Sleep Timing in Teens Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Delayed Sleep Phase
Interventions: OTHER: Increase morning bright light|OTHER: Decrease evening blue light|BEHAVIORAL: Sleep scheduling|BEHAVIORAL: Monitor sleep, mood, and substance use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced (Inoperable) or Metastatic Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Capivasertib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Fludarabine phosphate|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation|RADIATION: Fractionated total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immunoadsorption to Treat Severe Atopical Dermatitis Associated With Excessively High Serum IgE Levels
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: PROCEDURE: immunoadsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy & Tolerance of Urgo 310 3166 Dressing in Local Venous or Mixed Leg Ulcers
Status: COMPLETED
Conditions: Ulcers, Leg
Interventions: DEVICE: Urgo 310 3166 dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Brain Stimulation for Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Mild Neurocognitive Disorder|Cognitive Decline|Mental Deterioration|Cognitive Dysfunction|Memory Decline|Memory Loss|Memory Impairment
Interventions: DEVICE: Active rTMS (Bilateral DLPFC)|DEVICE: Active rTMS (Bilateral LPC)|DEVICE: Placebo rTMS (Inactive)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Oral Application of Gastrografin on the Meconium Evacuation in Very Low Birth Weight Infants
Status: COMPLETED
Conditions: Meconium Ileus|Very Low Birth Weight Infant
Interventions: DRUG: Gastrografin|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
Status: RECRUITING
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage|Intracerebral Hemorrhage|Liver Failure|Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: Transcranial Doppler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Metabolism of Danicopan in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Danicopan: Powder-In-Capsule 1|DRUG: Danicopan: Powder-In-Capsule 2|DRUG: Danicopan: Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Iodine-131 Anti-B1 Antibody (Tositumomab and Iodine I 131 Tositumomab) for Previously Untreated, Advanced-stage, Low Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Tositumomab and Iodine I 131 Tositumomab (Anti-B1 Antibody and Iodine-131 Anti-B1 Antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study Between EDP-305, Midazolam, Caffeine and Rosuvastatin in Healthy Volunteers.
Status: COMPLETED
Conditions: NASH
Interventions: DRUG: Midazolam|DRUG: Caffeine|DRUG: Rosuvastatin|DRUG: EDP-305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition
Status: WITHDRAWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inspiratory Muscle Training on Breast Cancer Patients Undergoing Surgery
Status: COMPLETED
Conditions: Post-operative Breast Cancer
Interventions: OTHER: inspiratory muscle training|OTHER: Aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Peptic Ulcer
Interventions: DRUG: Lafutidine|DRUG: Irsogladine maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ExAblate Treatment of Medication Refractory Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Medication-refractory Obsessive Compulsive Disorder (OCD)
Interventions: DEVICE: ExAblate Transcranial MRgFUS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-arm, Open-label, Multi-center Phase II Clinical Study to Evaluate the Safety and Efficacy of Toripalimab Injection (JS001) Combined With Bevacizumab as the First-line Therapy for Advanced Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma (HCC)
Interventions: COMBINATION_PRODUCT: Toripalimab combined with Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPIRIT Small Vessel Registry
Status: TERMINATED
Conditions: Coronary Artery Disease|Atherosclerosis|Myocardial Ischemia
Interventions: DEVICE: 2.25 mm XIENCE V® Everolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis
Status: UNKNOWN
Conditions: Hypertension, Renovascular
Interventions: DEVICE: Angioplasty with paclitaxel eluting balloon|DEVICE: Angioplasty with plain old balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Response Relationship of NN5401 in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec/insulin aspart|DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation on Pain Relief of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Cooled versus thermocoagulant Radiofrequency Ablation in pain relief of knee osteoarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-HER2 PET in Evaluating the Efficacy of Anti-HER2 Therapy for Urothelial Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: 18F-HER2 PET
Interventions: DIAGNOSTIC_TEST: 18F-HER2 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter Phase II Study of Stereotactic Radiotherapy for Centrally Located Lung Tumors (STRICT-LUNG STUDY) and Ultra-centrally Located Lung Tumors (STAR-LUNG STUDY).
Status: RECRUITING
Conditions: Lung Cancer|Metastases to Lung|Radiotherapy Side Effect
Interventions: PROCEDURE: STRICT LUNG|PROCEDURE: STAR LUNG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Cyclophosphamide, and G-CSF Followed By Combination Chemotherapy in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant Followed By Rituximab and GM-CSF for Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: adjuvant therapy|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Controlled Release Arbaclofen Placarbil (XP19986) in Patients With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: XP19986 CR|DRUG: Placebo for XP19986 CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prescription of Benzodiazepines by General Practitioners: Characteristics of Prescribing Trend and Implementation of an Online Educational Program
Status: COMPLETED
Conditions: Anxiety|Prescription Drug Abuse and Dependency
Interventions: BEHAVIORAL: ePrimaPrescribe online educational program|BEHAVIORAL: ComunicaSaudeMental online educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Value of Dynamic Monitoring of Early Recurrence of Hepatocellular Carcinoma After Radical Resection Based on CTCS
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Circulating Tumor Cell|Recurrence|Surgery
Interventions: DIAGNOSTIC_TEST: circulating tumor cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of TRPH-222 in Patients With Relapsed and/or Refractory B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Lymphoma, B-Cell|Lymphoma, Non-Hodgkin|Lymphoma, Mantle-Cell|Lymphoma, Marginal Zone|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Follicular
Interventions: DRUG: TRPH-222
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Psychosocial Factors Associated With Diagnostic Delay in Advanced Basal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Basal Cell, Malignant
Interventions: OTHER: Semi-structured interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Rapid Thrombelastography and Conventional Coagulation Testing for Haemostatic Resuscitation in Trauma
Status: COMPLETED
Conditions: Acute Coagulopathy
Interventions: BIOLOGICAL: Blood product transfusion based on conventional coagulation tests.|BIOLOGICAL: Blood product transfusion based on rapid thrombelastography (r-TEG) results.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pulmonary Hypertension Biorepository and Registry
Status: RECRUITING
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension|Pulmonary Hypertension Due to Left Heart Disease|Pulmonary Hypertension, Primary|Pulmonary Hypertension Due to Lung Diseases and Hypoxia|Pulmonary Hypertension, Primary, 4|Pulmonary Hypertension, Primary, 2|Pulmonary Hypertension, Primary, 3|Chronic Thromboembolic Pulmonary Hypertension
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IFN-free Combination Therapy in HCV-infected Patients Treatment-naive:HCVerso1
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin (RBV)|DRUG: BI 201335 (Faldaprevir)|DRUG: Ribavirin (RBV)|DRUG: BI 207127|DRUG: BI 201335 (Faldaprevir)|DRUG: Ribavirin (RBV)|DRUG: BI 207127|DRUG: Faldaprevir (BI 201335)|DRUG: BI 207127
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients
Status: RECRUITING
Conditions: Critical Illness|Vitamin D Deficiency|Covid19
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Navigation for the Treatment of Pertrochanteric Fractures With the Gamma 3 Nail
Status: UNKNOWN
Conditions: Femoral Fractures|Fracture Fixation, Internal|Trochanteric Fractures
Interventions: DEVICE: FluoroMap 3D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABT-751 With Chemotherapy for Relapsed Pediatric ALL
Status: TERMINATED
Conditions: Recurrent Pediatric ALL|Relapsed Pediatric ALL|Acute Lymphoblastic Leukemia|Refractory Pediatric ALL
Interventions: DRUG: ABT-751|DRUG: Dexamethasone|DRUG: PEG-asparaginase|DRUG: Doxorubicin|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Cyclophosphamide|DRUG: 6-thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotid Ultrasound Under Pulsed-wave Doppler Mode to Check the Pulse in Cardiopulmonary Arrest Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Arrest
Interventions: DEVICE: Carotid ultrasound under pulsed-wave doppler mode
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p