pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Efficacity and Safety of Deep Brain Stimulation (DBS) in Chronic and Treatment-Resistant Cluster Headache(CH)
Status: COMPLETED
Conditions: Cluster Headache
Interventions: PROCEDURE: setting-up of an electrode in deep brain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin in the Prevention of Post-Coronary Angioplasty Acute Kidney Injury
Status: SUSPENDED
Conditions: Acute Kidney Injury|Percutaneous Coronary Intervention
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant fowlpox-tyrosinase vaccine|BIOLOGICAL: vaccinia-tyrosinase vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Test of the Comparison Between Trans-rectal and Trans-perineal Biopsy of Prostate
Status: UNKNOWN
Conditions: Complication
Interventions: PROCEDURE: trans-rectal to perform the prostate biopsy|PROCEDURE: trans-perineal to perform the prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study Examining the Safety and Efficacy of Doxorubicin Drug Eluting Microspheres Transarterial Embolization in the Setting of Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: doxorubicin, superabsorbent polymer microspheres, embolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valopicitabine When Administered Alone and in Combination With Interferon to Treatment-Naive Patients With Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: valopicitabine|DRUG: pegylated interferon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
Status: UNKNOWN
Conditions: Functional Constipation|Irritable Bowel Syndrome|Probiotics|Colonoscopy
Interventions: DRUG: Live Combined Bifidobacterium and Lactobacillus|DRUG: Normal saline|DRUG: Basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution From PET-DOPA in Glioblastoma Re-irradiation - A Randomized Phase II Study
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Simultaneous-integrated boost with IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of the Safety of 4 Different Doses of Autologous Muscle Derived Cells as Therapy for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Cell Therapy
Interventions: BIOLOGICAL: autologous muscle cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study of E7070 in Patients With Renal Cell Carcinoma
Status: COMPLETED
Conditions: Kidney Neoplasms|Carcinoma, Renal Cell|Adenocarcinoma, Renal Cell
Interventions: DRUG: E7070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Self Fixating Mesh to Mesh Fixation With Metallic Tacks in Laparoscopic Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia|Adult
Interventions: DEVICE: Self fixating group|DEVICE: Tacker fixation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study)
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Tear Arthropathy
Interventions: BIOLOGICAL: Stem-cell treatment|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-Rich Fibrin Dressing in the Management of Free Gingival Graft
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: A free gingival graft|DEVICE: A Platelet-Rich Fibrin dressing|DEVICE: A non-eugenol-based dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
Status: COMPLETED
Conditions: Obesity|Diabetes|High Blood Pressure|Dyslipidemia
Interventions: BEHAVIORAL: Healthy lifestyle and adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Palifermin in Increasing CD4 Counts in Treatment-Experienced HIV Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Palifermin|DRUG: Palifermin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Electrical Impedance Tomography for the Diagnosis of Chronic Rejection in Lung Transplants Recipients
Status: COMPLETED
Conditions: Transplantation, Heart-Lung|Chronic Lung Allograft Dysfunction|Bronchiolitis Obliterans Syndrome
Interventions: OTHER: EIT|OTHER: Salbutamol nebulisation and with CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)
Status: COMPLETED
Conditions: Hypopituitarism|Central Diabetes Insipidus|Panhypopituitarism|Psychological Disorder|Social Isolation|Hypothalamic Diseases|Pituitary Diseases|Oxytocin Deficiency
Interventions: DRUG: Experimental: CRH administration|DRUG: Control: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Family Health Team High-Intensity Interval Training
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: High-Intensity Interval Training Physical Activity (PA) Advice|OTHER: Population-Based Physical Activity (PA) Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function
Status: RECRUITING
Conditions: Racial Disparities|Blood Pressure|Cardiovascular Risk Factor|Renal Function
Interventions: DIETARY_SUPPLEMENT: MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Palliative Radiotherapy With or Without Carboplatin
Status: TERMINATED
Conditions: Lung Cancer|Head and Neck Cancer|Metastatic Cancer
Interventions: COMBINATION_PRODUCT: irradiation + carboplatin|COMBINATION_PRODUCT: irradiation + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Are the Effects of Lower Limb Dysmetria on Gluteus Medius and Erector Spinae Musculature?
Status: COMPLETED
Conditions: Muscular Disorders, Atrophic
Interventions: OTHER: To evaluate the response of an orthopedic insole|OTHER: evaluate activation of musculature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Sunscreen Dispensers in Parks Visited by Teenagers
Status: RECRUITING
Conditions: Skin Neoplasm|Adolescent Behavior|Sunscreening Agents
Interventions: BEHAVIORAL: Dispensers, Flyers, Enhanced Signage + a social media component delivered by teen ambassadors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations
Status: COMPLETED
Conditions: Metabolic Acidosis|Antiepileptic Drugs|Craniotomy|Anesthesia Management
Interventions: PROCEDURE: Arterial Blood Gas Base Deficit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amniotic Membrane Graft In Syntomathic Bullous Keratopathy
Status: COMPLETED
Conditions: Bullous Keratopathy
Interventions: PROCEDURE: Implant of amniotic membrane grafts|DEVICE: Therapeutic contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab (ABX-EGF) Monotherapy in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastases
Interventions: DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: BCG|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Relationship Among Sarcopenia, Preperitoneal Fat Thickness and Cholecystectomy
Status: COMPLETED
Conditions: Sarcopenia|Cholecystectomy
Interventions: DIAGNOSTIC_TEST: sarcopenia assessment|DIAGNOSTIC_TEST: visceral fat thickness measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Psoriasis
Interventions: DRUG: Silymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation
Status: COMPLETED
Conditions: Transplantation Infection|Epstein-Barr Virus Infections|Cytomegalovirus Infections
Interventions: DRUG: Valacyclovir|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Mini-dystrophin Gene to Treat Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: rAAV2.5-CMV-minidystrophin (d3990)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Spinal Mobility Reeducation in Patients Treated for a Lumbar Spinal Stenosis After Epidural Infiltration
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: Control group (C)|OTHER: Test group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Revisional Bariatric Surgery Experience
Status: COMPLETED
Conditions: Bariatric Surgery|Revisional Bariatric Surgery|Obesity Associated Disorder
Interventions: OTHER: Laparoscopic mini gastric by-pass|OTHER: LaparoscopicRe-sleeve gastrectomy|OTHER: Laparoscopic Roux-en-Ygastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Regular Electrotherapy in Patients With Chronic Non-specific Neck Pain and Low-back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain|Chronic Pain|Back Pain Without Radiation
Interventions: DEVICE: StimaWELL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BOSCOT : A Randomised Controlled Trial of Cognitive Behavioural Therapy in Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CORT125134 Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CORT125134|DRUG: Matching Placebo of CORT125134|DRUG: Mifepristone|DRUG: Prednisone|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Dose-Effect Relationship of Wenxin Granules in the Treatment of Atrial Premature Beats
Status: RECRUITING
Conditions: Atrial Premature Complexes
Interventions: DRUG: Normal-dose Wenxin Granules|DRUG: 1/2 Normal-dose Wenxin Granules|DRUG: Twice Normal-dose Wenxin Granules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Games on Memory Reconsolidation and Trauma Symptoms
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Trauma
Interventions: BEHAVIORAL: Visuospatial Task (VST)|BEHAVIORAL: Word Association Task (WAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Wound Healing in Diabetic Ulcers by Sitagliptin
Status: WITHDRAWN
Conditions: Diabetic Foot
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Mandibular Fractures
Interventions: PROCEDURE: Open Reduction & Internal Fixation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Life-style Interventions for Modulating the Brain Phenotype of Takotsubo Cardiomyopathy
Status: COMPLETED
Conditions: Takotsubo Cardiomyopathy
Interventions: OTHER: Exercise program|OTHER: Cognitive behavioural therapy|OTHER: Standard clinical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Refractory/Relapsed Lymphoid Malignancies
Status: COMPLETED
Conditions: T-cell Lymphoma|Aggressive B-cell Lymphoma|Non-Hodgkin's Lymphomas|Indolent B-cell Lymphoma
Interventions: DRUG: Decitabine|DRUG: Tetrahydrouridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy With ACF Followed by Chemoradiation Therapy for Adv. Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: paclitaxel albumin-stabilized nanoparticle formulation|DRUG: Cisplatin|DRUG: Fluorouracil|RADIATION: Intensity modulated radiation therapy|DRUG: Cetuximab|PROCEDURE: Quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in the United States Using Electronic Medical Records (EMR) to Assess Effectiveness of Afatinib (Gilotrif) Following Pembrolizumab and Chemotherapy in the Treatment of Metastatic Squamous Cell Carcinoma of the Lung
Status: COMPLETED
Conditions: Squamous Non-small Cell Lung Cancer
Interventions: DRUG: Second line (2L) afatinib|DRUG: Second line chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine Patch|DRUG: Nicotine Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: STOP Trial - Sandostatin LAR Depot Trial for the Optimum Prevention of Chemotherapy Induced Diarrhea
Status: COMPLETED
Conditions: Neoplasms|Diarrhea
Interventions: DRUG: Sandostatin LAR Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Febuxostat|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ThisCART7 in Patients With Refractory or Relapsed T Cell Malignancies
Status: UNKNOWN
Conditions: T-Acute Lymphoblastic Leukemia|T-cell Non-Hodgkin Lymphoma|T-cell Acute Lymphoblastic Lymphoma
Interventions: BIOLOGICAL: ThisCART7 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Infusion During Laparoscopic Adrenalectomy
Status: COMPLETED
Conditions: Pheochromocytoma
Interventions: DRUG: dexmedetomidine|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treating Periodontal Infection: Effects on Glycemic
Status: COMPLETED
Conditions: Periodontal Disease|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Supra-gingival scaling and placebo|PROCEDURE: Subgingival scaling and metronidazole|PROCEDURE: Subgingival scaling and doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Iodine-131 Anti-B1 Antibody Consolidation for Patients With Non-Hodgkin's Lymphoma Following First-line CHOP
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: tositumomab and iodine I-131 tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM
Status: COMPLETED
Conditions: Fatty Liver|Diabetes Mellitus, Type 2
Interventions: DRUG: Ginger|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Trials of Sintilimab as Consolidation Therapy After Radical Concurrent Chemoradiotherapy in Locally Advanced Unresectable ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin+Capecitabine+Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ONO-1078 in Patients With Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: Placebo|DRUG: Pranlukast hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First Complete Response.
Status: NOT_YET_RECRUITING
Conditions: Neuroblastoma
Interventions: DRUG: Naxitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease
Status: UNKNOWN
Conditions: Moyamoya Disease
Interventions: OTHER: bypass surgery and indrect bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Moderate Dose Omega 3 Fatty Acid Supplement in Premenopausal Women at High Risk for Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Omega-3 Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Exposure to OMT Prevents Long LOS
Status: COMPLETED
Conditions: Prematurity
Interventions: OTHER: osteopathic manipulative treatment|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Power Laser and Exercise in Osteoarthritis of the Knee: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Laser|OTHER: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Aurora Xi New Nomogram Software 2.0
Status: NOT_YET_RECRUITING
Conditions: Apheresis Related Hypotension
Interventions: DEVICE: Aurora Xi New Nomogram Software 2.0|DEVICE: Aurora Xi Currently Approved Software 1.3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Sex and Obesity: Effects on Heart Failure Study
Status: COMPLETED
Conditions: Obesity|Heart Failure
Interventions: PROCEDURE: PET (Positron Emission Tomography)|PROCEDURE: Echocardiogram|RADIATION: ^15O-water|RADIATION: 1-^11C-palmitate|RADIATION: 1-^11C-glucose
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home Air Purification for Eosinophilic COPD
Status: ENROLLING_BY_INVITATION
Conditions: COPD|Eosinophilia
Interventions: DEVICE: Air purifier|DEVICE: Sham air purifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 7 Day's of Erlotinib Neo-adjuvant, Followed by Adjuvant Erlotinib-gemcitabine in Pancreatic Cancer Patients
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Genomic Medicine at VA Study
Status: RECRUITING
Conditions: Coronary Artery Disease|Atrial Fibrillation|Type 2 Diabetes|Colorectal Cancer|Breast Cancer|Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Polygenic risk score (PRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of LBH589 in Adult Patients With Refractory Chronic Myeloid Leukemia (CML) in Chronic Phase
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia in Chronic Phase
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence (BE) Study of Test Griseofulvin 500 Milligram (mg) Tablets Versus Reference and Dose Proportionality Study of Test Griseofulvin 250 mg and 500 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Antifungal Agents
Interventions: DRUG: Griseofulvin 500 mg|DRUG: Griseofulvin 250 mg|DRUG: Reference Griseofulvin 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Children's Books to Brochures for Safe Sleep and Infant Reading Education During Prenatal Care
Status: COMPLETED
Conditions: Sudden Unexplained Infant Death|Child Rearing|Literacy
Interventions: BEHAVIORAL: Sleep Baby, Safe and Snug|BEHAVIORAL: Read Baby, Every Day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Type of General Anesthesia Maintenance on Exhaled Nitric Oxide and Eosinophil Blood Count
Status: COMPLETED
Conditions: Anesthesia|Exhaled Nitric Oxide|Eosinophil Blood Count
Interventions: PROCEDURE: maintenance with sevoflurane|PROCEDURE: maintenance with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effect on Lung Function and ECG When a Combination of Tiotropium Plus Olodaterol is Administered to Patients With COPD Either From a Single Inhaler or Each Compound is Administered After Each Other From Two Different Inhalers
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: olodaterol|DRUG: tiotropium|DRUG: Placebo|DRUG: tiotropium|DRUG: olodaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: BI655130 (SPESOLIMAB) Induction Treatment in Patients With Moderate-to-severe Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
Status: RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma|Previously Treated Amyloid Light-chain (AL) Amyloidosis
Interventions: DRUG: JNJ-79635322
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial of CL2020 Cells for Neonatal Hypoxic Ischemic Encephalopathy
Status: COMPLETED
Conditions: Hypoxia-Ischemia, Brain
Interventions: BIOLOGICAL: CL2020 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Dapagliflozin on Peak VO2 in HFrEF
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Maximal functional capacity by cardiopulmonary exercise testing|DIAGNOSTIC_TEST: Echocardiography|BEHAVIORAL: Evaluation of health related quality of life|DIAGNOSTIC_TEST: Submáximal functional capacity assesment by 6 minutes walk test|OTHER: Clinical evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of A-60444 in Adults With Respiratory Syncytial Virus (RSV) Infection Following HSCT
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: A-60444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
Status: RECRUITING
Conditions: Brain Metastases|Nonsmall Cell Lung Cancer Stage III
Interventions: DIAGNOSTIC_TEST: MRI of the Brain|OTHER: Blood draws|OTHER: Quality of Life Questionnaires|DRUG: Gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patients Pregnant Women With or Without Primary Antiphospholipid Antibody Syndrome
Status: RECRUITING
Conditions: Preeclampsia|Immunologic Disease|Antiphospholipid Antibody Syndrome Primary|Pregnancy Complications|Pregnancy, High Risk|Rheumatic Diseases
Interventions: OTHER: Collection of epidemiological and anamnestic data and collection of biological material (peripheral blood)|OTHER: Collection of epidemiological and anamnestic data and collection of biological material (peripheral blood)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG)
Status: COMPLETED
Conditions: Glaucoma, Angle-Closure|Cataract
Interventions: PROCEDURE: combined phacotrabeculectomy|PROCEDURE: trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vaginal Estrogen Cream on Subjective and Objective Symptoms of Urodynamic Stress Incontinence
Status: WITHDRAWN
Conditions: Stress Urinary Incontinence
Interventions: DRUG: Vaginal ERT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bone-Conducted Stimulation on Rotary Chair Time Constants in Patients With Vestibular Migraines
Status: RECRUITING
Conditions: Vestibular Migraine
Interventions: DEVICE: Otolith Device Active|DEVICE: Otolith Device Inactive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma
Status: RECRUITING
Conditions: Advanced Solid Tumors Cancer|Advanced Urothelial Carcinoma|Oral Drug Administration|Open Label
Interventions: DRUG: FX-909
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 8.4% Sodium Bicarbonate Locks in Intestinal Failure
Status: RECRUITING
Conditions: Intestinal Failure|CRBSI - Catheter Related Bloodstream Infection
Interventions: DRUG: Sodium bicarb lock
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Analgetic Effectiveness of a Lidocaine Loaded Hemostatic, Bioresorbable Putty
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Orthostat-L|DEVICE: Orthostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probing the Dry Weight (DW) by Bioimpedance (BIA): Which is the Gold Standard Between Clinical DW and BIA DW?
Status: UNKNOWN
Conditions: Uremia|Complication of Hemodialysis
Interventions: OTHER: achievement of the DW by means of the BIA DW (RE.S.T.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics Study to Assess Abiraterone Acetate Capsule and Tablet Formulations in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Neoplasms
Interventions: DRUG: Stage 1 Group 1: abiraterone acetate|DRUG: Stage 1 Group 2: abiraterone acetate|DRUG: Stage 2: abiraterone acetate|DRUG: Stage 3: abiraterone acetate|DRUG: Stage 3: glucocorticoid|DRUG: Stage 4: abiraterone acetate|DRUG: Stage 4: glucocorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insecticide Resistance Management in Burkina Faso and Côte d'Ivoire
Status: UNKNOWN
Conditions: Malaria
Interventions: DEVICE: Insecticidal paint|DEVICE: Larvicide|BIOLOGICAL: Ivermectin|BEHAVIORAL: IEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of KAI-1678 to Treat Subjects With Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Placebo|DRUG: KAI-1678|DRUG: Ketorolac Tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrial Effects of Sildenafil in Frozen-Thawed Cycles in Women With Thin Endometrium
Status: UNKNOWN
Conditions: IVF|Endometrial Receptivity
Interventions: DRUG: Sildenafil Citrate|OTHER: Placebo|DRUG: Estradiol Valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TELMINUVO to Stage 2 Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: TELMINUVO Tab. (80/2.5mg)|DRUG: TELMINUVO Tab. (80/5mg)|DRUG: S-amlodipine 2.5mg|DRUG: S-amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Transmission of Anti-interferon Type 1 Alpha Autoantibodies From Mother to Child Via the Placental Barrier
Status: NOT_YET_RECRUITING
Conditions: Woman Suffering From a Pathology Frequently Associated With the Presence of These Anti-autoantibodies Type-I Interferons
Interventions: OTHER: Pregiferon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Synthetic Human Secretin-Enhanced MRCP in Subjects With Abnormalities of the Pancreas
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: RG1068 (synthetic human secretin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Uremic Toxins Clearance With Expanded Hemodialysis
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Expanded Hemodialysis|PROCEDURE: High-flux Conventional Hemodialysis|PROCEDURE: Hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose GnRHa Early Luteal Phase Down Regulation Versus GnRHa Ultra-short Protocol for Poor Ovarian Response
Status: UNKNOWN
Conditions: Subfertility, Female|Ovulation Disorder
Interventions: DRUG: Diphereline (Triptorelin embonate)|DRUG: Decapeptyl (Triptorelin)|DRUG: human menopausal gonadotropin|DRUG: human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ONCOXIN® in Oral Mucositis, Appetite and Body Mass in Cancer Patients.
Status: COMPLETED
Conditions: Mucositis Oral
Interventions: DIETARY_SUPPLEMENT: Oncoxin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Double-Blind Study of the Efficacy and Safety of Valdecoxib Compared to Placebo for Treatment of Post- Cholecystectomy Surgery Pain
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy|Pain
Interventions: DRUG: placebo|DRUG: valdecoxib|DRUG: valdecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Detection of IDH1/2 Mutation in Gliomas
Status: UNKNOWN
Conditions: Glioma|IDH1/IDH2 Mutation
Interventions: RADIATION: Spectro-MRI|OTHER: Dosage of free circulating plasmatic DNA|OTHER: Dosage of D-2HG in the urine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Fatigue on Core Endurance, Dynamic Balance and Player Performance in Adolescent Football Players
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Fatigue protocol (repeated sprint ability)|OTHER: Sham Comparator: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Rifampin (RIF) on the Pharmacokinetics (PK) of Oral Cabotegravir (CAB) in Healthy Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: CAB|DRUG: RIF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of Ramelteon on Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon and Placebo (25 possible combinations total)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioids and Loneliness
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder|Loneliness|Social Isolation
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy for Perceived Social Isolation|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of TMC435 in Combination With PegIFN Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment-Naïve or Treatment-Experienced, Chronic Hepatitis C Virus Genotype-4 Infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus
Status: COMPLETED
Conditions: Subjective Tinnitus
Interventions: DRUG: Neramexane mesylate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells.
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: DIAGNOSTIC_TEST: lncRNA signature analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The China Mviv Registry
Status: RECRUITING
Conditions: Bioprosthesis Failure|Mitral Stenosis With Insufficiency|Mitral Stenosis|Mitral Regurgitation|Heart Failure
Interventions: DEVICE: Transseptal Transcatheter Mitral valve-in-valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy
Status: RECRUITING
Conditions: Bladder Carcinoma
Interventions: BEHAVIORAL: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Vision System for Mandibular Trajectory Assessment in Women With Mild Temporomandibular Joint Disorder
Status: COMPLETED
Conditions: Mandibular Deviation
Interventions: DIAGNOSTIC_TEST: Mandibular movements recordings by a mono vision system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intermittent Multifunctional Nutrition Tube in Cerebral Palsy and Dysphagia
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: systemic therapy|DEVICE: Intermittent Oro-Esophageal Tube Feeding|DEVICE: Persistent Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precise Robotically IMplanted Brain-Computer InterfacE
Status: RECRUITING
Conditions: Tetraplegia/Tetraparesis|Quadriplegia|Cervical Spinal Cord Injury|Amyotrophic Lateral Sclerosis|Quadriplegia/Tetraplegia|Tetraplegic; Paralysis
Interventions: DEVICE: N1 Implant|DEVICE: R1 Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Impact of Photopheresis in the Prevention of Acute Rejection in Highly Sensitized de Novo Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant Rejection
Interventions: OTHER: Extracorporeal Photopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Multiple-micronutrients Supplementation on Growth and Iron Status of Indigenous Children in Malaysia
Status: COMPLETED
Conditions: Underweight|Stunted Growth|Wasting|Anemia
Interventions: DIETARY_SUPPLEMENT: Multiple-micronutrients supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy People to Measure the Amount of BI 655130 in the Blood After Injecting Different Doses Into Different Parts of the Body
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: R - Low dose of BI 655130|DRUG: T1 - Low dose of BI 655130|DRUG: T2 - Low dose of BI 655130|DRUG: T3 - High dose of BI 655130
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group
Status: RECRUITING
Conditions: Acute Respiratory Failure
Interventions: DEVICE: Asymmetric High flow nasal cannula|DEVICE: Standard(symmetric) High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Status: COMPLETED
Conditions: Local Anaesthetic Drug Adverse Reaction
Interventions: PROCEDURE: Dental Local Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients Who Completed VITALITY-ALS (CY 4031)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: tirasemtiv
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting
Status: RECRUITING
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Vericiguat (Verquvo, BAY1021189)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of NAFLD in T2DM Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: NAFLD|T2D|Type 2 Diabetes|Fatty Liver, Nonalcoholic
Interventions: DIAGNOSTIC_TEST: FibroScan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison for Efficacy and Safety of Bowel Preparation Between Oral Sulfate Table and 2L-polyethylene Glycol/Ascorbate in Elderly
Status: UNKNOWN
Conditions: Colonic Disease|Intestinal Disease
Interventions: DRUG: OST|DRUG: 2L-PEG/Asc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Conformal Partial Breast Irradiation With CyberKnife After Resection for Early Stage Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Stereotactic radiotherapy delivered by CyberKnife|RADIATION: stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation Studies of Curative Effect of Fu-zheng-qu-zhuo Oral Liquid in Treatment of Ischemic Nephropathy
Status: UNKNOWN
Conditions: Atherosclerotic Renal Artery Stenosis
Interventions: DRUG: Fu-zheng-qu-zhuo oral liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|RADIATION: Radiation Therapy|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT