pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the PK of BMS-927711 in Patient With Migraine During Acute Migraine and Non-migraine Condition
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: BMS-927711 (CGRP Antagonist)|DRUG: BMS-927711 (CGRP Antagonist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin or Galantamine Versus Placebo for the Treatment of Negative Symptoms and Cognitive Impairments in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Galantamine|OTHER: Placebo-Oxytocin|OTHER: Placebo-Galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Effect of LY3556050 on Metformin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3556050|DRUG: Metformin|DRUG: Iohexol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Effects of Itraconazole and Rifampicin on the Single-Dose Pharmacokinetics of JNJ-53718678 in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-53718678|DRUG: Itraconazole|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability During Anesthesia Induction in Adults.
Status: RECRUITING
Conditions: The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability
Interventions: DRUG: ketamine- dexmeditomidine admixure|DRUG: Propofol, Lidocaine and fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Induction Chemotherapy and Immunotherapy Combined Radiotherapy With or Without Concurrent Chemotherapy for Stage III-IVa NPC
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: without concurrent cisplatin chemotherapy|DRUG: with concurrent cisplatin chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis
Status: ENROLLING_BY_INVITATION
Conditions: Myalgic Encephalomyelitis|Chronic Fatigue Syndrome
Interventions: OTHER: Photobiomodulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Haploidentical Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Individual Antithymocyte globulin|DRUG: Antithymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine Response of the Organism to Polytrauma
Status: COMPLETED
Conditions: Polytrauma
Interventions: DRUG: Vitamin D3 + anabolic substance|OTHER: No Vitamin D3 + anabolic substance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Intake of Bacopa Monneiri on Vascular Oxidative Stress
Status: COMPLETED
Conditions: Oxidative Stress|Cardiovascular Diseases|Bacopaside II|Bacopa Monnieri|Endothelial Dysfunction|Aquaporin 1|AQP1
Interventions: DIETARY_SUPPLEMENT: Bacopa monnieri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)
Status: RECRUITING
Conditions: Metastatic Solid Tumors|Advanced Solid Tumors
Interventions: DRUG: MK-0472|BIOLOGICAL: Pembrolizumab|DRUG: MK-1084
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Ruxolitinib in Combination With Methylprednisolone
Status: COMPLETED
Conditions: aGVHD|Stem Cell Transplant Complications
Interventions: DRUG: Ruxolitinib 10 mg twice a day combined with Corticosteroids|DRUG: Ruxolitinib 5 mg twice a day combined with Corticosteroids|DRUG: Ruxolitinib 5 mg once a day combined with Corticosteroids|DRUG: Ruxolitinib 2.5 mg once a day combined with Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Evaluate the Effect of Aging of Multiple Doses of GLPG1205 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Elderly
Interventions: DRUG: GLPG1205 50mg q.d.|DRUG: Placebo oral capsule|DRUG: GLPG1205 250 loading dose and 50mg q.d. maintenance dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE)
Status: RECRUITING
Conditions: Colonic Neoplasms
Interventions: PROCEDURE: Japanese pathological investigation|PROCEDURE: European pathological investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhibition of Disease Progression in Hepatitis C-infected Patients With Compensated Liver Cirrhosis (P03811) (COMPLETED)
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Liver Cirrhosis
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031)|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol Versus Doxercalciferol in the Treatment of Secondary Hyperparathyroidism in Chronic Kidney Disease
Status: COMPLETED
Conditions: Renal Osteodystrophy
Interventions: DRUG: doxercalciferol|DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Disability of Children With Cerebral Palsy Using Motor Transcranial Magnetic Stimulation
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: high intensity iTBS|OTHER: low intensity iTBS|OTHER: sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: OTHER: avocado|OTHER: potato or chickpea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sling Suspension Versus Gym Balls in the Treatment of Juvenile Spinal Osteochondrosis
Status: COMPLETED
Conditions: Juvenile Osteochondrosis of Spine
Interventions: PROCEDURE: Sling suspension using red cord|PROCEDURE: Gym ball exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tolerability and Efficacy of Erythropoietin (EPO) Treatment in Spinal Shock: Comparative Study Versus Methylprednisolone (MP)
Status: TERMINATED
Conditions: Spinal Cord Injury
Interventions: DRUG: Erythropoietin|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C)
Status: COMPLETED
Conditions: Chronic Hepatitis C|Cirrhosis|Portal Hypertension
Interventions: DEVICE: Fibroscan: Liver and Spleen elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PRediction of Vagal Nerve Stimulation EfficaCy In Drug-reSistant Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: OTHER: Statistical model for the prediction of VNS efficacy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Letrozole Versus Clomiphene Citrate for Ovulation Induction in Women With Poly Cystic Ovary Syndrome ( PCOS )
Status: UNKNOWN
Conditions: Anovulation|Polycystic Ovary Syndrome
Interventions: DRUG: Letrozole|DRUG: Clomiphene citrate|DRUG: hcg hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi Syndrome
Status: UNKNOWN
Conditions: Silver Russell Syndrome|Prader-Willi Syndrome
Interventions: DRUG: Anastrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study
Status: TERMINATED
Conditions: Cognitive Decline|Intracerebral Hemorrhage|Dementia, Vascular|Cerebral Small Vessel Diseases|Hypertension|Stroke Hemorrhagic
Interventions: DRUG: telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Digital Home-Exercise Therapy Application For Patients With Non-Surgical Knee Injuries
Status: COMPLETED
Conditions: Knee Injuries|Knee Osteoarthritis|Patellofemoral Syndrome
Interventions: DEVICE: Limber Digital Application|BEHAVIORAL: Physical therapy Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation in Treatment and Prophylaxis of Chronic Migraine in Patients With no Prophylactic Treatment for the Last 3 Months
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: DEVICE: transcranial magnetic stimulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation
Status: COMPLETED
Conditions: Fluid Loss|Symptom Complex, Triple|Emergencies
Interventions: DRUG: Lactated Ringer Solution|DRUG: Normal Saline 0.9% Infusion Solution Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eldecalcitol for GLucocorticoid Induced OsteopoRosIs Versus Alfacalcidol
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Eldecalcitol|DRUG: Alfacalcidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: arsenic trioxide|DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Positive|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Durvalumab|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using the "Edwards" EV1000 Clinical Platform NI in Lymphatic Venous Anastomosis
Status: UNKNOWN
Conditions: Hemodynamic Monitoring|Perioperative Care|Outcome Assessment
Interventions: DEVICE: Standard group|DEVICE: ClearSight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Caffeine on Ocular Circulation in High Myopes
Status: COMPLETED
Conditions: High Myopia|Choroid
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Long Term Transcranial Pulse Stimulation (TPS) on Older Adults With Mild Neurocognitive Disorder (NCD)
Status: RECRUITING
Conditions: Mild Neurocognitive Disorder
Interventions: DEVICE: Transcranial Pulse Stimulation (TPS)|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain
Status: TERMINATED
Conditions: Internal Derangement of Hip|Acetabular Labrum Tear
Interventions: DRUG: Ropivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Changes In Mammographic Breast Density
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: BZA 20 mg/CE 0.45 mg|DRUG: BZA 20 mg/CE 0.625 mg|DRUG: Raloxifene 60 mg|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-angiogenic Targeted Drugs Plus Rg3 to Improve the Efficacy of TACE for Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Anti-angiogenic Targeted Drugs|DRUG: Ginsenoside Rg3|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility
Status: UNKNOWN
Conditions: Azoospermia|Oligozoospermia
Interventions: BIOLOGICAL: Lipoaspiration and SVF introduction.|DRUG: Standard therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baduanjin Exercising Effects on Sub-clinical Hypothyroidism and Cognitive Problems
Status: RECRUITING
Conditions: Subclinical hypothyroïdism|Cognitive Impairment
Interventions: BEHAVIORAL: Baduanjin exercising
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia|Mental Disorders|Psychotic Disorders
Interventions: GENETIC: Retrospective study of frozen samples|GENETIC: Prospective study of fresh samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin Versus Hydroxizin for Pre Operative Anxiety in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Preoperative Anxiety
Interventions: DRUG: Melatonin 5 MG Sublingual Tablet|DRUG: Hydroxyzine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effects of Egg Ingestion on Endothelial Function in Adults With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Egg supplementation|DIETARY_SUPPLEMENT: Egg substitute|DIETARY_SUPPLEMENT: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: HEPPI: Efficacy of a Cognitive-Emotional Intervention for Homebound Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Depressive Symptoms|Anxiety State
Interventions: BEHAVIORAL: HEPPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Erlotinib and Bevacizumab as Second-line Treatment in Patients With Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and ISIS 2503 in Treating Patients With Advanced or Metastatic Cancer of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: ISIS 2503|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With Double Expression Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: The First Affiliated Hospital of Nanchang University
Interventions: DRUG: Orelabrutinib+R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study to Investigate How a Study Medicine (NNC9204- 1177) Affects Blood Levels of Other Medicines in Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers|Overweight|Obesity
Interventions: DRUG: NNC9204-1177|DRUG: Cocktail of 5 already approved drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK/Efficacy Bridging Study of ASTX727 in Chinese Subjects With Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: IV Decitabine|DRUG: Decitabine and cedazuridine|DRUG: only Decitabine and cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Finnish Community Randomized Psychotherapy Effectiveness Study for Major Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: BEHAVIORAL: Interpersonal Psychotherapy|BEHAVIORAL: Psychoeducational Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Treatment for Hyperglycemic Acute Ischemic Stroke
Status: TERMINATED
Conditions: Stroke, Acute|Hyperglycemia|Diabetes
Interventions: DRUG: Pioglitazone 45 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Tolerance and Efficacy Study of RSD1235 in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Vernakalant Injection 20 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mastectomy With Retention of the Nipple-areola Complex, Robot-assisted or Not, and / or Immediate or Seconday Reconstruction by Latissimus Dorsi Flap, Robot-assisted or Not.
Status: NOT_YET_RECRUITING
Conditions: Mastectomy|Breast Reconstruction
Interventions: DEVICE: Robot-assisted|PROCEDURE: Not robot-assisted surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information Improvement for Surgical Patients Through Portable Video Media
Status: COMPLETED
Conditions: Prostatic Hyperplasia|Bladder Cancer
Interventions: OTHER: Informed consent trough a portable video media|OTHER: Written informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A First-in-Human Study of LY3009385 in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3009385|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: DRUG: duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vascular and Metabolic Effects of Vytorin vs Simvastatin
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: placebo|DRUG: vytorin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Red Grape Seed Extract on Lipid Profile and Oxidized Low-Density Lipoprotein (OX-LDL)
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Grape Seed Extract (Vitagrape)|DRUG: Placebo of Grape Seed Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buccal Mucosa Healing Trial With Tissue Matrix Placement
Status: COMPLETED
Conditions: Tissue Grafts
Interventions: PROCEDURE: Tissue Matrix Graft Placement|PROCEDURE: No Stitches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Healthy Nutrition Program and Virtual Reality Applications on Body Composition
Status: NOT_YET_RECRUITING
Conditions: Obesity|Virtual Reality|Body Composition|Healthy Nutrition|Physical Fitness
Interventions: DEVICE: non-immersive virtual reality|BEHAVIORAL: Healty Diet Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis
Status: UNKNOWN
Conditions: Conscious Sedation Failure During Procedure
Interventions: DRUG: Ketamine/Propofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Fecal Capsule on Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: PROCEDURE: Fecal Microbiota Transplant（FMT）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of NEPA in Preventing Postoperative Nausea and Vomiting After General Anesthesia Gastrointestinal Cancer Surgery: A Single-Center Retrospective Study
Status: RECRUITING
Conditions: General Anesthesia Gastrointestinal Cancer Surgery
Interventions: DRUG: NEPA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 68Ga-P16-093 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga-PSMA-617|DRUG: 68Ga-P16-093
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: CHOP regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Influence of the Phases of the Menstrual Cycle on Glycemic Control When Performing Aerobic Exercise in Women With T1D
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Aerobic session
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Different Local Anesthetics in Cervical Facet Medial Branch Blockade
Status: COMPLETED
Conditions: Pain, Neck
Interventions: PROCEDURE: facet median block with prilocain|PROCEDURE: facet median block with lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin Hydrochloride Liposome and Carboplatin in Treating Patients With Recurrent, Stage III, or Stage IV Primary Endometrial Cancer
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: DRUG: carboplatin|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases
Status: UNKNOWN
Conditions: Congestive Heart Failure|Asthma|Chronic Obstructive Pulmonary Disease|Cystic Fibrosis
Interventions: DEVICE: Respiratory Sensor measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: lithium carbonate|DRUG: Depakote-ER|DRUG: risperidone|DRUG: olanzapine|DRUG: paroxetine|DRUG: bupropion|DRUG: lamotrigine|DRUG: venlafaxine|DRUG: tranylcypromine|DRUG: mirtazapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Role of Repetitive Trans Cranial-magnetic Stimulation in Craving Reduction Among Opioid Use Disorder Patients
Status: UNKNOWN
Conditions: Substance Use Disorders
Interventions: DEVICE: repetitive trans magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Gadobutrol 1.0 Molar ( Gadavist ) in Patients for Central Nervous System (CNS) Imaging
Status: COMPLETED
Conditions: Central Nervous System Diseases
Interventions: DRUG: Gadobutrol (Gadavist, Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of HIFU-AR on Blood Loss Reduction in Patients With Liver Metastases Requiring Hepatectomy
Status: TERMINATED
Conditions: Liver Metastasis
Interventions: DEVICE: Pre-coagulation of the liver parenchyma with HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Pulpal Oxygen Saturation Level After Administering Mepivacaine With and Without Vasoconstrictor
Status: COMPLETED
Conditions: LOCAL ANESTHESIA
Interventions: DRUG: 3% Mepivacaine Hydrochloride|DRUG: 2% Mepivacaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Metabolic and Bariatric Therapies
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Obesity, Morbid|Obesity Associated Disorder|Bariatric Surgery Candidate|Fistula, Gastric|Roux-en-y Anastomosis Site|Ulcer, Gastric|Abdominal Pain|Abdominal Obesity|Complication of Surgical Procedure|Complication of Treatment|Complication,Postoperative|Weight Gain|Weight Loss|Leak, Anastomotic|Delayed Gastric Emptying Following Procedure
Interventions: PROCEDURE: Primary Obesity Endoscopic Procedures|PROCEDURE: Endoscopic Revision of Bariatric Surgical Procedures|PROCEDURE: Bariatric Surgery Procedures|DEVICE: Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction|DEVICE: Intragastric Balloon|DEVICE: Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal|DEVICE: Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy|DEVICE: Aspiration Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Noise Control During Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Active noise cancelling|DEVICE: Passive noice cancelling|DEVICE: Active noise cancelling with music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Theta-Burst-Stimulation in Recurrent Stroke Recovery
Status: UNKNOWN
Conditions: Stroke|Neurorehabilitation
Interventions: DEVICE: Magstim Super Rapid2 System|DEVICE: Magstim Super Rapid2 System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rituximab and Combination Chemotherapy in Treating Older Patients With Previously Untreated B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|OTHER: pharmacological study|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Method to Treat Hereditary Cerebellar Ataxia - Umbilical Cord Mesenchymal Stem Cells Transplantation
Status: UNKNOWN
Conditions: Hereditary Cerebellar Ataxia.
Interventions: OTHER: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncogenic Role of Engrailed (EN)-2 in Epithelial Ovarian Neoplasms
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: GENETIC: Immunohistochemical staining of normal and neoplastic ovarian tissues by anti human Engrailed-2 antibody.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of CT1812 in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: CT1812|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Plus Tremelimumab Combined With Proton Therapy for HNSCC
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Durvalumab Plus Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise in Patients With Osteoarthritis of the Hip
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Strength training|PROCEDURE: Nordic Walking|PROCEDURE: Unsupervised home based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics Study of BMS-866949 in Healthy Subjects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: BMS-866949|DRUG: BMS-866949|DRUG: BMS-866949|DRUG: BMS-866949|DRUG: BMS-866949|DRUG: BMS-866949|DRUG: BMS-866949|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Randomized Trial of Buccal Compared to Oral Misoprostol Following Mifepristone for Medical Abortion up to 63 Days LMP
Status: COMPLETED
Conditions: Abortion, Induced
Interventions: DRUG: 800 mcg misoprostol via oral or buccal administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Establish Diagnostic Models Based on Olfactory Function and Odor-induced Brain Activation for Diabetes-Related Cognitive Impairment
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive assessments|OTHER: Olfactory function measurements|OTHER: Functional magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project
Status: COMPLETED
Conditions: Depression|Depression, Postpartum|Depressive Disorder|Depressive Disorder, Major|Mood Disorders|Pregnancy Complications|Puerperal Disorders
Interventions: DEVICE: Philips EnergyUp EnergyLight HF3419/01|DEVICE: Philips EnergyUp EnergyLight HF3419/01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estimate the Efficacy of HD6610 Granule for Oxaliplatin-induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Peripheral Neuropathy
Interventions: DRUG: FOLFOX regimen|DRUG: HD6610 Granule|DRUG: HD6610 Granule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment
Status: TERMINATED
Conditions: Retinal Detachment
Interventions: DRUG: denufosol tetrasodium (INS37217) Intravitreal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuronostatin - a Glucagonotropic Agent in Humans?
Status: RECRUITING
Conditions: Type 1 Diabetes|Hypoglycemia|Type1diabetes
Interventions: OTHER: Infusion of either NST or placebo at different blood glucose levels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk Evaluation and Education for Alzheimer's Disease (REVEAL) IV
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: APOE genotype and Alzheimer's disease risk disclosure|BEHAVIORAL: Alzheimer's disease risk disclosure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Trial, Phase I|Neuroendocrine Tumors|Thymoma|Mesothelioma
Interventions: DRUG: 177Lu-DOTA-TATE + olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
Status: COMPLETED
Conditions: Anesthesia Intubation Complication
Interventions: DRUG: Dexmedetomidine nebulization|DRUG: Lidocaine nebulization|DRUG: Dexmedetomidine IV|DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Hip Resurfacing and Cementless Metal-on-metal Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Hip resurfacacing|PROCEDURE: Cementless total hip arthroplasty with m-o-m bearings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Octreotide, Tamoxifen, and Chemotherapy in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: octreotide pamoate|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Medical Expulsive Therapy After Extracorporeal Shock Wave Lithotripsy (ESWL) in Pediatric Urolithiasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Tamsulosin|Extracorporeal Shock Wave Lithotripsy|Stone, Kidney|Stone, Urinary|Pediatric Disorder
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Attention/Working Memory Rehabilitation in Multiple Sclerosis: A Pilot Project Using Cogmed Working Memory Training
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Cogmed Working Memory Training (CWMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Gemcitabine Plus Cisplatin in the Treatment of TNBC Patients Following Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (United States)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Ibuprofen|DRUG: celecoxib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Of Exemestane Versus Continued Tamoxifen In Postmenopausal Women With Early Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Tamoxifen|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Action Observation Training (AOT) in the Achievement of Urinary Continence in Men After Robot-assisted Laparoscopic Prostatectomy (RALP)
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: OTHER: Action observation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum IL-6 and Soluble IL-6 Receptor in Severe COVID-19 Pneumonia Treated With Tocilizumab
Status: UNKNOWN
Conditions: COVID-19|Severe Pneumonia
Interventions: DRUG: Tocilizumab 20 MG/ML Intravenous Solution [ACTEMRA]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: ACURATE neo2™ Transfemoral TAVR System|DEVICE: Medtronic CoreValve TAVR System|DEVICE: Edwards SAPIEN 3 TAVR System|DEVICE: ACURATE Prime™ Transfemoral TAVR System XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Doxycycline Treatment in EM Patients
Status: COMPLETED
Conditions: Erythema Chronicum Migrans
Interventions: DRUG: Doxycycline 100 MG Oral Tablet bid, 7 days|DRUG: Doxycycline 100 MG Oral Tablet bid, 14 days|DRUG: Controls without a history of lyme disease.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus MOVIPREP® Using 2-Day Split-Dosing and 1-Day Morning Split-Dosing Regimen in Adults.
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma|Colon Cleansing
Interventions: DRUG: NER1006, 2-Day Split-Dosing|DRUG: NER1006,1-Day Morning Split-Dosing|DRUG: MOVIPREP, 2-Day Split-Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Whole Body Vibration on Postmenopausal Risk-factors in Elderly Women
Status: TERMINATED
Conditions: Postmenopausal
Interventions: DEVICE: vertical vibration device (Vibrafit whole body vibration platform)|DEVICE: side alternating vibration device (Board 3000 whole body vibration platform)|BEHAVIORAL: stretching and wellness (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy of AMG 706 to Treat Advanced Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Advanced Gastrointestinal Stromal Tumor
Interventions: DRUG: AMG 706
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Lidocaine on Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adaptive Radiation for Abdominopelvic Metastases
Status: RECRUITING
Conditions: Neoplasm - Soft Tissue Pelvis Malignant Secondary|Malignant Neoplasm of Stomach
Interventions: RADIATION: Adaptive Stereotactic Body Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants Aged ≥18 Years with Moderate-to-Severe Plaque or Active Psoriatic Arthritis in India
Status: ACTIVE_NOT_RECRUITING
Conditions: Plaque Psoriasis|Psoriatic Arthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial)
Status: COMPLETED
Conditions: Delirium|Agitation
Interventions: DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Malaria Vaccine Candidate SumayaVac-1 in Healthy Adults Aged 18-45 Years Living in a Malaria Endemic Country
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: SumayaVac-1(SUM-101)|BIOLOGICAL: Verorab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Label Efficacy and Safety Study of the Elbasvir/ Grazoprevir Fixed Dose Combination Patients With Chronic HCV GT1b
Status: UNKNOWN
Conditions: Chronic Hepatitis C Genotype 1B|Metabolic Syndrome|Fibrosis, Liver|Cirrhoses, Liver
Interventions: DRUG: Elbasvir/ Grazoprevir 50/100 mg fixed dose combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans Canal Tympanoplasty With Local Anesthesia Using Fat Graft and "TachoSil"
Status: NOT_YET_RECRUITING
Conditions: Tympanic Membrane Perforation
Interventions: PROCEDURE: Tympanoplasty performed under local anesthesia using fat graft and "Tachosil".
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Empowerment-based Psycho-behavioral Program on Persons With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: 13-week multimodal intervention|BEHAVIORAL: 5-week health education programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Myoblasts to Duchenne Muscular Dystrophy (DMD) Patients
Status: UNKNOWN
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: Myoblast transplantation|PROCEDURE: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JMT202
Status: ENROLLING_BY_INVITATION
Conditions: Healthy Subjects
Interventions: DRUG: JMT202|DRUG: Placrbo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT