pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sonohysterography , 3D Ultrasonography and Hysteroscopy in Assessment of Uterine Factor in Cases of Female Infertility
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: hysteroscopy|DEVICE: two dimensional ultrasound|DEVICE: saline sonohysterography|DEVICE: three dimensional ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inferior Vena CAVA and Lung UltraSound-guided Therapy in Acute Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Acute Heart Failure
Interventions: OTHER: CAVAL US-guided Therapy|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EndoVascular Aortic Repair With Sac Embolization for the Prevention of Type II Endoleaks (the EVAR-SE Study)
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm|Endoleak
Interventions: PROCEDURE: Coil embolization of aneurysm sac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of [14C]Acp-196 (Acalabrutinib) in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Acalabrutinib|DRUG: Microtracer [14C]ACP-196
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [BrainConnexion] - Neurodevice Phase I Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Tetraplegia|Tetraplegia/Tetraparesis|Spinal Cord Injuries|Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Locked-in Syndrome|Muscular Dystrophies
Interventions: DEVICE: BrainConnexion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed With Hemophilia A
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Damoctocog alfa pegol (Jivi, Bay94-9027)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HIV Patients With Chronic Hepatitis C Genotype 1 Infection Who Failed Previously to Peginterferon /Ribavirin
Status: COMPLETED
Conditions: Hepatitis C|HIV Infections|COINFECTION
Interventions: DRUG: boceprevir|DRUG: Ribavirin|DRUG: Peginterferon alfa-2a|DRUG: Peginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Hepatico-gastrostomy With Hot Giobor
Status: NOT_YET_RECRUITING
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: EUS-guided hepatico-gastrostomy would be performed with Niti-S HOT Giob
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Duration of Antibiotic Treatment in Early Onset Infection in Newborns.
Status: RECRUITING
Conditions: Early-Onset Neonatal Sepsis|Antibiotic Side Effect
Interventions: OTHER: Individualized treatment duration strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Alcohol Withdrawal With Oral Baclofen
Status: COMPLETED
Conditions: Alcohol Withdrawal Delirium
Interventions: DRUG: Baclofen|DRUG: Placebo|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Quadratus Lumborum Block for Lumbar Spinal Surgery
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality IQ Patient Simulation Physician Practice Measurement and Engagement
Status: COMPLETED
Conditions: Diabetes|Hypertension|Depression|Osteoarthritis|Asthma|Pain|Heart Failure
Interventions: OTHER: Continuing Medical Education|OTHER: Quality IQ Patient Simulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Helping People Adhere to Their Varenicline Treatment by Co-creating a Conversational Agent: A Feasibility Study
Status: RECRUITING
Conditions: Medication Adherence|Smoking Cessation
Interventions: OTHER: Varenicline healthbot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial)
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Panobinostat|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Comparative Evaluation of 3 Dimensional Changes of Dentition in Post Orthodontic Patients With Immediate vs Delayed (Post 24 Hours) Retainer Delivery
Status: RECRUITING
Conditions: Relapse
Interventions: OTHER: immediate orthodontic retainer delivery|OTHER: delayed orthodontic retainer delivery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of COBRA PzF Stenting to Reduce Duration of Triple Therapy
Status: UNKNOWN
Conditions: Angina, Stable|Angina, Unstable|Anticoagulants
Interventions: DEVICE: COBRA PzF|DEVICE: Drug Eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Treatment of Primary Progressive Aphasia
Status: COMPLETED
Conditions: Primary Progressive Aphasia|Repetitive Transcranical Magnetic Stimulation
Interventions: DEVICE: Magstim rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Potassium and Acetazolamide on People With Andersen-Tawil Syndrome
Status: TERMINATED
Conditions: Andersen-Tawil Syndrome
Interventions: DIETARY_SUPPLEMENT: Potassium|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Adaptations to Weight Loss With and Without Exercise
Status: RECRUITING
Conditions: Obesity|Metabolic Disease|Metabolic Syndrome|Insulin Sensitivity|Insulin Resistance|Weight Loss
Interventions: BEHAVIORAL: MICT Exercise|BEHAVIORAL: No Exercise (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu Arteritis
Status: UNKNOWN
Conditions: Takayasu Arteritis
Interventions: DRUG: Infliximab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of Expanded Cord Blood T Cells
Status: WITHDRAWN
Conditions: Stem Cell Transplantation|Leukemia|Lymphoma|Pediatric Disorders
Interventions: RADIATION: Total Body Irradiation (TBI)|DRUG: Melphalan|DRUG: Thiotepa|DRUG: Fludarabine|DRUG: Rituximab|DRUG: Etoposide|DRUG: Anti-thymocyte globulin (ATG)|DRUG: Mycophenolate Mofetil (MMF)|DRUG: Tacrolimus|PROCEDURE: Cord Blood Infusion|DRUG: G-CSF|PROCEDURE: Ex vivo expanded T cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: imatinib mesylate|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisolone|DRUG: therapeutic hydrocortisone|DRUG: vincristine sulfate|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of ACD856
Status: COMPLETED
Conditions: Alzheimer Disease|Cognition Disorder
Interventions: DRUG: ACD856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for Systematic Neonatal Screening for Lysosomal Storage Diseases Using Tandem Mass Spectrometry
Status: UNKNOWN
Conditions: Neonatal Screening|Lysosomal Storage Diseases
Interventions: PROCEDURE: Additional blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative CHG Cloth on Healthy Subjects
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Chlorhexidine Gluconate|OTHER: Vehicle|DRUG: DynaHex-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral Nutritional Supplementation Combined With Impedance Vectors
Status: COMPLETED
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis|Overhydration|Undernutrition
Interventions: DIETARY_SUPPLEMENT: Proteinex and Enterex DBT Victus Laboratories|PROCEDURE: Dry weight adjustment through BIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Adipose-derived Stem Cells (AdMSCs) for COVID-19
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: autologous adipose-derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Long-term Simultaneous Motor Cortex Stimulation and Balance Training
Status: RECRUITING
Conditions: Coordination and Balance Disturbances
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraspinal Transplantation of Autologous ADRC in ALS Patients
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Cell-based therapy of autologous adipose derived regenerative cells transplanted intraspinally and intrathecally in ALS patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Integra in Coverage of Radial Forearm Free Flap Donor Site Defect
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DEVICE: Integra plus STSG|PROCEDURE: STSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study About Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: saxagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System
Status: ACTIVE_NOT_RECRUITING
Conditions: Thoracic Aorta Aneurysm|Aneurysm, Ruptured|Aortic Aneurysm
Interventions: DEVICE: penetrating atherosclerotic ulcer, aorta branch cardiovascular implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Ocular Melanoma|Metastatic Uveal Melanoma
Interventions: COMBINATION_PRODUCT: Melphalan (3 mg/kg IBW) with Hepatic Delivery System (HDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Arsenic Trioxide, and Melphalan in Treating Patients Undergoing an Autologous Stem Cell Transplant For Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: Arsenic trioxide|DRUG: Bortezomib|DRUG: Melphalan|BIOLOGICAL: Autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Whole-Food, Plant-Based Diet for Patients With Low-Risk Chronic Lymphocytic Leukemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia Stage A(0)
Interventions: OTHER: Whole-food, plant-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.
Status: UNKNOWN
Conditions: Primary Postpartum Haemorrhage
Interventions: DRUG: Misoprostol|DRUG: vitamin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study to Demonstrate the Bioequivalence of Lecanemab Supplied in Vials and a Single-Use Auto-Injector (AI) in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lecanemab|DRUG: Lecanemab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: VivaSight-SL™ Versus Bronchoscopy for Percutaneous Tracheotomy
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DEVICE: conventional bronchoscopy|DEVICE: VivaSight-SL tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetic Properties of SYP-1018 (Voriconazole-loaded PNP) and Voriconazole (Vfend)
Status: COMPLETED
Conditions: Systemic Mycotic Infection
Interventions: DRUG: SYP-1018 200mg|DRUG: Voriconazole 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iTBS-DCS in Obsessive Compulsive Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: iTBS repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham rTMS|DRUG: D-cycloserine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics|Drug Interactions|Hypercholesterolemia|Immunosuppression
Interventions: DRUG: 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany|DRUG: 1 tablet Rapamune(R) (sirolimus), Wyeth Pharma, Germany|DRUG: 1 tablet Ezetrol(R) + 1 tablet Rapamune(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Chromium Supplementation on Intracytoplasmatic Sperm Injection (ICSI) Outcomes in Polycystic Ovary Syndrome Ladies
Status: COMPLETED
Conditions: PCOS
Interventions: DIETARY_SUPPLEMENT: Chromium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections.
Status: RECRUITING
Conditions: Urinary Tract Infections
Interventions: DRUG: Hiprex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure
Status: COMPLETED
Conditions: Nerve Block|Analgesia|Pectus Excavatum
Interventions: PROCEDURE: ESPB group|PROCEDURE: TPVB group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunotherapy Using Pluripotent Killer-Human Epidermal Growth Factor Receptor-2 (PIK-HER2) Cells for the Treatment of Advanced Gastric Cancer With Liver Metastasis
Status: UNKNOWN
Conditions: Liver Metastasis|Gastric Cancer
Interventions: BIOLOGICAL: PIK-HER2|BIOLOGICAL: DC-PMAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones
Status: COMPLETED
Conditions: Kidney Stone|Ureteral Stone
Interventions: DEVICE: SOLTIVE™ Premium SuperPulsed Laser Fiber System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis
Status: COMPLETED
Conditions: Pruritus|Prurigo Nodularis
Interventions: DRUG: 5mg Serlopitant Tablets|DRUG: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Carbohydrate Fueling to Enhance Physical Performance During Energy Deficit
Status: RECRUITING
Conditions: Energy Supply; Deficiency
Interventions: DIETARY_SUPPLEMENT: BAL:GLU|DIETARY_SUPPLEMENT: BAL:GLU+FRU|DIETARY_SUPPLEMENT: DEF:GLU|DIETARY_SUPPLEMENT: DEF:GLU+FRU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Propofol-Dexmedetomıdıne And Propofol- Remıfentanıl In Hysteroscopıc Operations.
Status: COMPLETED
Conditions: Deep Sedation|Ambulatory Surgery|Ambulatory Surgical Procedure
Interventions: COMBINATION_PRODUCT: Propofol-Dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Treadmill Training on Motor Function, Balance, and Spasticity Reduction in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Treadmill Training In CP child|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Waukesha Smiles: Dental Outreach to Low-income Waukesha Children
Status: COMPLETED
Conditions: Dental Caries
Interventions: BEHAVIORAL: Educational Intervention|BEHAVIORAL: Referral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females
Status: COMPLETED
Conditions: Cervical Cancers|Vulvar Cancer|Vaginal Cancer|CIN1|CIN2|CIN 3|AIS|Invasive Carcinoma|Mild Dysplasia of Vulva|Moderate Dysplasia of Vulva|Vin III|VaIN1|VaIN2|VaIN3|Genital Wart
Interventions: BIOLOGICAL: 9-valent HPV Recombinant Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Panobinostat & Bortezomib in Pancreatic Cancer Progressing on Gemcitabine Therapy
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Bortezomib|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Photopheresis Post Angioplasty
Status: TERMINATED
Conditions: Stable Angina Pectoris|Unstable Angina Pectoris|Silent Ischemia
Interventions: PROCEDURE: Photopheresis Post Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BOLD Functional Magnetic Resonance Imaging (fMRI) and Cerebral Blood Flow Measurements as Biomarkers for Cognition Enhancing Drugs (3134-006)
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: MK3134|DRUG: Comparator: Placebo|DRUG: Donepezil|DRUG: MK3134
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
Status: COMPLETED
Conditions: Current or Recent History of Atrial Fibrillation
Interventions: DRUG: bucindolol hydrochloride|DRUG: metoprolol succinate|OTHER: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating BMD in Participants ≥50 Years Old Switching From EVG/COBI/FTC/TAF or EVG/COBI/FTC/TDF to ABC/DTG/3TC
Status: UNKNOWN
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Triumeq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Combined Hormonal Contraceptives on UPA
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Ulipristal Acetate|DRUG: Levonorgestrel (LNG)/Ethinyl estradiol birth control pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Manual Therapy on the Upper Cervical Spine Combined With Exercise vs Isolated Exercise in Patients With Cervicogenic Headache.
Status: COMPLETED
Conditions: Cervicogenic Headache|Headache
Interventions: OTHER: Manual Therapy and Exercises|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds
Status: COMPLETED
Conditions: Lower Extremity Wound Infected|Venous Stasis Ulcers
Interventions: DEVICE: VAC VeraFlo with Dakins Instillation|DEVICE: VAC Ulta Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes Prevention|Executive Function (Cognition)
Interventions: BEHAVIORAL: Aerobic exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cannabidiol and Prolonged Exposure
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Prolonged Exposure|DRUG: Cannabidiol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Single Glucocorticoid Hip Fracture Hip Fracture Surgery
Status: COMPLETED
Conditions: Delirium - Postoperative|Stress, Physiological
Interventions: DRUG: methylprednisolone sodium succinate|DRUG: placebo saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab Plus GX Versus Tislelizumab Plus GP in the Treatment of R/M NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Tislelizumab combined with GX|DRUG: Tislelizumab combined with GP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy Versus Radiofrequency Ablation for Unresectable, Small (≤ 3 cm) HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic Body Radiotherapy|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 28-Day Daily-dose Crossover Study of the Safety and Tolerability of SB-121 (Lactobacillus Reuteri With Sephadex® and Maltose) in Subjects, Ages 15 to 45 Years, Diagnosed With Autistic Disorder
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: SB-121|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: SB-509
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAlming Touch for People With Agitation or Other Behavioural Symptoms of DEMentia - A Randomized Feasibility Trial
Status: COMPLETED
Conditions: Dementia|Agitation,Psychomotor
Interventions: BEHAVIORAL: Calming Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of 99mTc-MIP-1404 SPECT/CT Imaging in Men With Prostate Cancer Undergoing Prostatectomy and/or Pelvic Lymph Node Dissection
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 99mTc-MIP-1404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess Efficacy, Long Term Safety and Tolerability of RT001 in Subjects With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: RT001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors
Status: COMPLETED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Burkitt Lymphoma|Childhood Diffuse Large Cell Lymphoma|Childhood Immunoblastic Large Cell Lymphoma|Childhood Nasal Type Extranodal NK/T-cell Lymphoma|Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor (PNET)|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Peripheral T-cell Lymphoma|Plasma Cell Neoplasm|Primary Systemic Amyloidosis|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Neuroblastoma|Recurrent Small Lymphocytic Lymphoma|Recurrent/Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Regional Neuroblastoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: DRUG: etoposide|DRUG: cyclophosphamide|DRUG: carmustine|DRUG: melphalan|DRUG: busulfan|DRUG: carboplatin|DRUG: thiotepa|RADIATION: total-body irradiation|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: autologous-autologous tandem hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HaemoDialysis Interventions to REduce Multi-Organ Dysfunction and Effect on Quality of Life Assessed by MRI Scanning
Status: COMPLETED
Conditions: Renal Failure|Cardiovascular Diseases|Congenital Disorders
Interventions: OTHER: HD, Magnetic Resonance Imaging (MRI) scans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors,Gastroenteropancreatic
Interventions: DRUG: Cabozantinib|DRUG: Lanreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranial Orthotic Device Versus Repositioning Techniques for the Management of Plagiocephaly: the CRANIO Randomized Trial
Status: UNKNOWN
Conditions: Plagiocephaly, Nonsynostotic
Interventions: DEVICE: Helmet|BEHAVIORAL: home therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Oral 2-Deoxy-D-Glucose (2DG) in Subjects With a Confirmed Diagnosis of Epilepsy
Status: COMPLETED
Conditions: Epilepsy; Seizure
Interventions: DRUG: Oral 2-Deoxy-D-Glucose (2DG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-Cigarette Aerosol, Conventional Cigarette Smoke, and Myocardial Perfusion
Status: TERMINATED
Conditions: Coronary Artery Disease|Myocardial Perfusion
Interventions: OTHER: Cigarettes|OTHER: E-cigarettes (nicotine free e-liquid)|OTHER: E-cigarettes (low nicotine e-liquid)|OTHER: E-cigarettes (high nicotine e-liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Physician Race and Gender on Simulated Patients' Ratings
Status: COMPLETED
Conditions: Bias, Racial|Bias, Sex|Patient Satisfaction|Physician-Patient Relations
Interventions: BEHAVIORAL: Simulated Black Male Physician|BEHAVIORAL: Simulated Black Female Physician|BEHAVIORAL: Simulated White Male Physician|BEHAVIORAL: Simulated White Female Physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessment of the Efficacy of a Fatigue Management Therapy in Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Fatigue Management Therapy|OTHER: TAU (Treatment as usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Rituximab in Participants With Refractory Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Refractory Large B-cell Lymphoma
Interventions: BIOLOGICAL: Axicabtagene Ciloleucel|DRUG: Rituximab|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Bronchodilators and Cardiac Repolarization
Status: COMPLETED
Conditions: Influence of Nebulized Bronchodilatators on Selected|Electrophysiological Parameters
Interventions: DRUG: Salbutamol 2,5 mg|DRUG: Salbutamol 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Patent Foramen Ovale (PFO) and Risk of Perioperative Stroke
Status: RECRUITING
Conditions: Patent Foramen Ovale
Interventions: DIAGNOSTIC_TEST: Diffusion-weighted Magnetic Resonance Imaging (DW-MRI)|DIAGNOSTIC_TEST: Transcranial Doppler (TCD)|DIAGNOSTIC_TEST: Transthoracic Echocardiogram (TTE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2)
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: CaPre|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial
Status: COMPLETED
Conditions: Substance Abuse
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography to Evaluate Ticagrelor and Clopidogrel
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: anti-CD19 CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT TAVR Abdomen Study
Status: RECRUITING
Conditions: Transcatheter Aortic Valve Replacement
Interventions: COMBINATION_PRODUCT: Iodinated Contrast Agent (Omnipaque)|DEVICE: Dual Energy CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Secukinumab 300 mg|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty
Status: COMPLETED
Conditions: Total Hip and Knee Arthroplasty
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Ropivacaine|DRUG: Bupivacaine|DRUG: Clonidine|DRUG: Ketorolac|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PRT-201 Administered Immediately After Radiocephalic Arteriovenous Fistula(AVF) Creation in Patients With Chronic Kidney Disease (CKD) (PATENCY-1)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: PRT-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between (MIPO)Submuscular Plate Fixation of Fracture Femur and Conservative Management With Thomas Splint in Children From 5 to 8 Years Old: A Randomized Clinical Study
Status: COMPLETED
Conditions: Femur Fracture
Interventions: PROCEDURE: Submuscular plating|PROCEDURE: Traction and casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of NMDA-enhancing and Antioxidant Treatments for Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: NMDAE plus AO|DRUG: NMDAE plus Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PF-00299804 in Patients With Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head Neck Cancer Squamous Cell Metastatic|Head Neck Cancer Squamous Cell Recurrent
Interventions: DRUG: PF-00299804
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antacid Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lesinurad 400 mg|DRUG: Tums 500 mg and 750 mg|DRUG: MINTOX 10 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observation Versus Post-surgery Radiotherapy After Complete Exeresis in Soft Tissues Members Sarcoma
Status: TERMINATED
Conditions: Soft Tissue Sarcoma of Members
Interventions: RADIATION: Radiotherapy|OTHER: absence of radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Presence of IBD Specific Antibodies (ASCA, ALCA, ACCA, AMCA) in the Sera of Patients With Spondyloarthropathy
Status: UNKNOWN
Conditions: Psoriatic Arthritis|Ankylosing Spondylitis|Undifferentiated Spondyloarthropathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Statin in Venous Dysfunction in Patients With Venous Thromboembolism Event
Status: UNKNOWN
Conditions: Venous Thromboembolism|Dyslipidemias
Interventions: DRUG: Rosuvastatin 20mg|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Case Management for Burns Care in Pakistan
Status: NOT_YET_RECRUITING
Conditions: Unintentional Burn Injury|Depression|Anxiety|Burns
Interventions: BEHAVIORAL: Integrated case manager care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Combining Spinal Manipulation and Dry Needling in Individuals With Low Back Pain
Status: COMPLETED
Conditions: Non-specific Low Back Pain
Interventions: PROCEDURE: Spinal manipulation|PROCEDURE: Dry needling|PROCEDURE: Spinal manipulation and dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HYPoxaEmic Respiratory Failure and Awake Prone Ventilation
Status: RECRUITING
Conditions: Respiratory Failure|Hypoxemia
Interventions: BEHAVIORAL: Awake prone position (APP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cauterization Versus ﬁbrin Glue for Conjunctival Autografting in Primary Pterygium Surgery
Status: RECRUITING
Conditions: Pterygium of Conjunctiva and Cornea
Interventions: PROCEDURE: Cauterization|PROCEDURE: Fibrin glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anesthesia Type on Pulmonary Function
Status: COMPLETED
Conditions: Anesthesia|Geriatric Patients
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Neuraxial anesthesia|DIAGNOSTIC_TEST: Spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Optimizing Bronchopulmonary Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Bronchopulmonary Disease|Diagnoses Disease
Interventions: OTHER: Screening|OTHER: Inclusion|OTHER: Chest CTscan and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Concomitant Administration of Erythromycin and Diltiazem on CYP3A Activity in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Erythromycin|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Addition of Single Dose of Oral Montelukast to Standard Treatment in Acute Asthma in Preschool Children.
Status: COMPLETED
Conditions: Asthma|Acute Asthma
Interventions: DRUG: montelukast 4 mg granule|DRUG: Montelukast placebo granüle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: PF-04455242|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Group Intervention for Interpersonal Skills
Status: RECRUITING
Conditions: Depressive Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: Kiesler Circle Training (KCT)|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The OPC for Optimal Delivery of Paclitaxel for the Prevention of Endovascular Restenosis - Above and Below the Knee
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Cardiovascular Disease|Peripheral Vascular Disease
Interventions: OTHER: Paclitaxel administration using the OPC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of B7H3 CAR-T Cells in Treating Advanced Liver Cancer
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: fhB7H3.CAR-Ts|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Paclitaxel Toxicity in Breast Cancer: The Roles of Physical Activity and Body Composition.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Paclitaxel Adverse Reaction|Chemotherapeutic Toxicity|Chemotherapeutic Agent Toxicity|Body Weight|Physical Inactivity
Interventions: DRUG: Paclitaxel Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5
Status: COMPLETED
Conditions: Inhibition of Plaque Formation (by Gingivitis-Index ≤1.5)
Interventions: DRUG: Octenidinedihydrochlorid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of MK-4827 for Treatment of Solid Tumors (MK-4827-005)
Status: TERMINATED
Conditions: Neoplasms|Solid Tumors
Interventions: DRUG: MK-4827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine Chemoradiation and TNP-470 Patients Locally Advanced, Nonmetastatic Adenocarcinoma of Pancreas
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: TNP-470
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physica System Total Knee Replacement Registry Study
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Traumatic Arthritis|Avascular Necrosis|Degenerative Joint Disease of Knee|Rheumatoid Arthritis|Deformity of Knee
Interventions: DEVICE: Physica Kinematic Retaining Knee System|DEVICE: Physica Cruciate Retaining Knee System|DEVICE: Physica Posterior Stabilized Knee System|DEVICE: Physica Cruciate Retaining Knee System with LMC Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT