pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases
Status: COMPLETED
Conditions: Gastric Ulcer (GU)|Duodenal Ulcer (DU)|Anastomotic Ulcer (AU)|Non-erosive Reflux Esophagitis Disease (NERD)|Reflux Esophagitis (RE)|Zollinger-Ellison Syndrome
Interventions: DRUG: D961H sachet 10 mg|DRUG: D961H capsule 10mg|DRUG: D961H capsule 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Cystic Fibrosis Diabetes
Status: TERMINATED
Conditions: Cystic Fibrosis|Prediabetes
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: BF2.649
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study for Patients Who Completed a Phase 3 Double-blind Study of PEG-uricase for Symptomatic Gout
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: pegloticase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expression of Erythroid Differentiation Regulator 1 (Erdr1) in Vitiligo
Status: UNKNOWN
Conditions: Erythroid Differentiation Regulator 1 (Erdr1) Cytokine
Interventions: OTHER: skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Caisson Transcatheter Mitral Valve Replacement (TMVR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Regurgitation|Mitral Valve Disease|Mitral Valve Failure|Mitral Disease|Valve Heart Disease|Valve Disease, Heart
Interventions: DEVICE: Transcatheter Mitral Valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Debio 1143-201 Dose-finding and Efficacy Phase I/II Trial
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cisplatin|RADIATION: Radiotherapy|DRUG: Debio 1143|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Bioavailability Study of Relatlimab in Combination With Nivolumab
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: relatlimab|DRUG: nivolumab|DRUG: rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research of Electroacupuncture and TENS in Patients With Rheumatoid Arthritis
Status: RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DEVICE: electroacupuncture|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency of Episodes of Hypoglycaemia During Treatment With Biphasic Insulin Aspart 30 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic human insulin 30|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Postoperative Pain of Three Single-use Adult Supraglottic Airway Devices in Short General Anesthetic Under Controlled Ventilation
Status: COMPLETED
Conditions: Pharyngolaryngeal Postoperative Pain
Interventions: PROCEDURE: Insertion of LMA-UNIQUE(TM) device|PROCEDURE: Insertion of LMA-SUPREME(TM) device|PROCEDURE: Insertion of I-GEL(R) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 22-gauge ProCore Needle v. Standard 22-gauge (P00030500)
Status: COMPLETED
Conditions: Quantity of Tissue Obtained|Quality of Tissue Obtained|Ease of Use of 22-gauge ProCore EBUS Needles and the Standard 22-gauge Needles
Interventions: OTHER: 22-gauge Standard Needle|OTHER: 22-gauge ProCore Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative Radiosurgery for the Treatment of High Grade Glioma, The NeoGlioma Study
Status: RECRUITING
Conditions: Malignant Glioma
Interventions: RADIATION: Radiation Therapy|RADIATION: Radiosurgery|PROCEDURE: Stereotactic Biopsy|DRUG: Temozolomide|PROCEDURE: Therapeutic Conventional Surgery|PROCEDURE: Tumor Treating Fields Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: ZG005 Powder for Injection|DRUG: Donafenib Tosilate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Sourdough Fermentation Improve Iron Uptake From Whole Grain Rye Bread?
Status: COMPLETED
Conditions: Iron Bioavailability|Anaemia
Interventions: OTHER: Whole grain rye bread|OTHER: Whole grain sourdough rye bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomised Ischaemic Mitral Evaluation (RIME) Trial
Status: COMPLETED
Conditions: Mitral Regurgitation|Coronary Artery Disease
Interventions: PROCEDURE: CABG + Mitral valve annuloplasty|PROCEDURE: CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating a Web Delivered Behavioral Parent Training Intervention for Rural Parents of Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Parenting|Parenting Intervention
Interventions: BEHAVIORAL: Attend Behavior Parent Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients
Status: COMPLETED
Conditions: Open Angle Glaucoma
Interventions: DRUG: Timolol & Dorzolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis
Status: WITHDRAWN
Conditions: Respiratory Failure|Volume Overload|Hypernatremia
Interventions: DRUG: Supplemental metolazone diuresis|DRUG: Placebo Comparator: Control-- furosemide (lasix) only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Hour Time Course of Striatal Dopamine D2 Receptor Occupancy of Ziprasidone: A PET Study
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: ziprazidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nurse Navigation Program on Symptom Management and Psychosocial Adjustment in Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer|Psycho-Oncology|Nursing
Interventions: BEHAVIORAL: individualized colorectal cancer education|BEHAVIORAL: psycho-oncological counseling|BEHAVIORAL: telephone support hotline service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Circulating Tumor DNA as Surgical Biomarker in Patients With PancrEatic Adenocarcinoma for Statement of Resectability
Status: RECRUITING
Conditions: PDAC - Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: ctDNA analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Effectiveness of PROCRIT (Epoetin Alfa) Dosing Every 2 Weeks Versus Once a Week in Anemic HIV-infected Patients
Status: TERMINATED
Conditions: Anemia|HIV
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ready to Use Supplementary Food in Moderate Childhood Malnutrition
Status: COMPLETED
Conditions: Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ready to Use Supplementary Food|DIETARY_SUPPLEMENT: Premix CSB-oil treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetic and Proof-of-Concept Study of ARN-509 (Apalutamide) in Castration-Resistant Prostate Cancer (CRPC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: ARN-509 (Phase 1)|DRUG: ARN-509 (Phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent LGX818 and MEK162 in Treating Patients With Metastatic Melanoma Who Have BRAFV600 Mutations
Status: WITHDRAWN
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: Raf kinase inhibitor LGX818|DRUG: binimetinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Modified Minimally Invasive Surgical Technique and Platelet Rich Fibrin With or Without Vitamin Pool A and C for Management of Periodontal Intrabony Defects
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Experimental: Modified minimally invasive surgical technique with PRF and vitamins A and C|PROCEDURE: Modified minimally invasive surgical technique with PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Goals for Epilepsy Clinic Visits Trial
Status: RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: BEHAVIORAL: Survey questionnaires|BEHAVIORAL: Epilepsy Visit Planner|BEHAVIORAL: Questionnaires for Providers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Swine-origin A/H1N1 Influenza Vaccines in Healthy European Adults and the Elderly
Status: COMPLETED
Conditions: Influenza|Swine-origin A/H1N1 Influenza
Interventions: BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated)|BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated)|BIOLOGICAL: Swine A/H1N1 influenza vaccine (split virion, inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or Rosuvastatin
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Midazolam|DRUG: Caffeine|DRUG: Rosuvastatin|DRUG: KW-6356
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Stereotactic Body Radiotherapy and 177Lu-PSMA-617 for the Treatment of Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617|PROCEDURE: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition, Diabetes and Pulmonary TB/HIV
Status: COMPLETED
Conditions: Tuberculosis|HIV|Diabetes
Interventions: DIETARY_SUPPLEMENT: Multimicronutrients|DIETARY_SUPPLEMENT: Energy and proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of CJ-30060 in Hypertensive Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hypertension With Hyperlipidemia
Interventions: DRUG: Amlodipine 10 mg + Valsartan 160 mg + Rosuvastatin 20 mg|DRUG: Amlodipine 10 mg + Valsartan 160 mg|DRUG: Valsartan 160 mg + Rosuvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate vs Delayed Loading of Two Implants Supporting a Mandibular Over Denture
Status: COMPLETED
Conditions: Implant Survival Using Immediate Loading Protocol
Interventions: PROCEDURE: dental implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food and Antacid on BIIB021 With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: BIIB021 and Food|DRUG: BIIB0121 and Antacid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of a Topical Antifungal Treatment for Tinea Cruris, Tinea Pedis and Tinea Corporis
Status: COMPLETED
Conditions: Tinea Pedis|Tinea Cruris|Tinea Corporis
Interventions: DRUG: Product 33525
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Butyrate on Colonic Health of Patients With Diarrhoea Predominant IBS and UC in Remission
Status: COMPLETED
Conditions: Gut Health
Interventions: OTHER: sodium butyrate|OTHER: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imaging of CB1 Receptors Using (11C)SD5024
Status: TERMINATED
Conditions: Healthy
Interventions: PROCEDURE: Brain Scan-PET|PROCEDURE: Brain Scan-MRI|PROCEDURE: Arterial Line|PROCEDURE: Venous Line|PROCEDURE: Blood Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Eye Mask Applied on Patients Undergoing Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Sleep Disorder|Pain, Postoperative
Interventions: BEHAVIORAL: eye mask|BEHAVIORAL: standart care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Competencies in Scientific Writing and Attendees' Satisfaction After Two Different Types of Training Courses: SCRIU-B Study
Status: ENROLLING_BY_INVITATION
Conditions: Scientific Writing Training Course
Interventions: OTHER: Scientific writing training course
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy
Status: NOT_YET_RECRUITING
Conditions: Somatostatin Receptor Positive|Gastrointestinal Neuroendocrine Tumors|Pheochromocytoma|Paragangliomas
Interventions: DRUG: 68Ga-DOTATATE|DRUG: [203Pb]VMT-alpha-NET|DRUG: [212Pb]VMT-alpha-NET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)
Status: WITHDRAWN
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis
Interventions: PROCEDURE: Patient controlled analgesia|DRUG: nurse-administered intermittent IV bolus opioid therapy (NAIBOD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meloxicam for Pain Management After Total Joint Arthroplasty (TJA)
Status: COMPLETED
Conditions: Total Knee Replacement|Total Hip Replacement
Interventions: DRUG: IV meloxicam|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Itolizumab (EQ001) to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity in Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: EQ001|DRUG: EQ001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Clinical Decision Support and Sleep Navigation (Sleep PASS)
Status: COMPLETED
Conditions: Sleep-Disordered Breathing|Obstructive Sleep Apnea|Sleep
Interventions: OTHER: CDS with Sleep Navigation|OTHER: CDS-only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing tDCS to Improve Dual Task Gait and Balance
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Traditional tDCS|OTHER: Traditional Sham|OTHER: Personalized tDCS|OTHER: Personalized Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post Sustained Virological Response (SVR) Hepatocellular Carcinoma (HCC) Screening
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|HCC|Hepatitis C|HCV
Interventions: BEHAVIORAL: Automated reminders|BEHAVIORAL: Patient navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Status: COMPLETED
Conditions: Bandages|Muscle Soreness
Interventions: OTHER: Kinesio Taping|OTHER: Placebo Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Femtosecond Laser-assisted Anterior Lamellar Keratoplasty
Status: COMPLETED
Conditions: Keratoconus|Corneal Opacity
Interventions: PROCEDURE: FS-ALK (Femtolaser-assisted anterior lamellar keratoplasty)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study of Upadacitinib in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Talimogene Laherparepvec With Cisplatin and Radiotherapy for Treatment of Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: BIOLOGICAL: Talimogene Laherparepvec|RADIATION: Radiation|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
Status: RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Monosodium glutamate|DIETARY_SUPPLEMENT: Quinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Exploratory Study of A-337 in the Management of Malignant Solid Dose Escalation and Expansion Phases
Status: NOT_YET_RECRUITING
Conditions: Recurrent or Metastatic Solid Tumors
Interventions: BIOLOGICAL: Recombinant Anti-EpCAM-CD3 Antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of JNJ-64041575 in Adult Participants With Various Degrees of Renal Function
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: JNJ-64041575
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cataract Surgery Technique and Ocular Clarity
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: cataract surgery with Centurion phacoemulsification system|PROCEDURE: cataract surgery with Quatera 700 phacoemulsification system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation for Cardiovascular Risk Reduction in People With Severe and Persistent Mental Illness
Status: RECRUITING
Conditions: Mental Illness Persistent|Cardiovascular Prevention
Interventions: BEHAVIORAL: Cardiac Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hyperthermic Intraperitoneal Chemotherapy for Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Hyperthermic intraperitoneal chemotherapy (HIPEC)|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intensive Therapy on Trunk and Lower Limbs in Children With Spastic Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Qualitative functional therapy|OTHER: Functional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Optimal Positive End-Expiratory Pressure on Oxygenation and Intrapulmonary Shunt During One-lung Ventilation
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DEVICE: compliance guided an optimal Positive End-Expiratory Pressure|DEVICE: PEEP level of 5 cmH2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease
Status: RECRUITING
Conditions: Rotator Cuff Tears|Rotator Cuff Tendinitis|Rotator Cuff Impingement|Injections|Glucocorticoids
Interventions: DRUG: FX006 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranberry for the Prevention of Urinary Tract Infections
Status: COMPLETED
Conditions: Diabetes|Urinary Infection
Interventions: DIETARY_SUPPLEMENT: ANTHOCRAN FITOSOMA|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
Status: SUSPENDED
Conditions: Metastatic Colorectal Cancer|KRAS G12C Mutations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache
Status: TERMINATED
Conditions: Headache
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAY1019036)|DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ТВ/Flu-05Е Vaccine for the Prevention of Tuberculosis Infection in BCG-vaccinated Volunteers Aged 18-50 Years
Status: COMPLETED
Conditions: Tuberculosis Infection
Interventions: BIOLOGICAL: TB/Flu-05E vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Omiganan (CLS001) Topical Gel Versus Vehicle in Female Subjects With Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Omiganan (CLS001) Topical Gel|DRUG: Vehicle Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of INCB053914 in Subjects With Advanced Malignancies
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: INCB053914|DRUG: I-DAC (Intermediate dose cytarabine)|DRUG: Azacitidine|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Versus Ilioinguinal/ Ilio-hypogastric Block in Children Undergoing Inguinal Surgeries
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Ilioinguinal/iliohypogastric nerve blocks|PROCEDURE: Erector spinae nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bikini Scarless Laparoscopic Cholecystectomy for Morbid Obesity as a Day Case.
Status: UNKNOWN
Conditions: Cholecystitis, Chronic
Interventions: OTHER: laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment With Pulsed Light and Photobiomodulation Before Laser Refractive Surgery
Status: RECRUITING
Conditions: Dry Eye|Dry Eye After LASIK-Laser in Situ Keratomileusis
Interventions: DEVICE: IPL+LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Ibudilast for Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorders
Interventions: DRUG: Ibudilast|OTHER: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock
Status: COMPLETED
Conditions: Septic Shock|Acute Kidney Injury
Interventions: OTHER: Haemodynamic management|OTHER: Haemodynamic management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of iPS Cell Generation From Patients With COPD
Status: COMPLETED
Conditions: Thoracic Diseases|Respiratory Tract Diseases|Cancer of Lung|Cancer of the Lung|Lung Cancer|Lung Diseases, Obstructive|COPD|Pulmonary Emphysema|Neoplasms, Lung|Neoplasms, Pulmonary|Pulmonary Cancer|Pulmonary Neoplasms|Carcinoma, Non-Small-Cell Lung|Carcinoma, Small Cell
Interventions: OTHER: Skin Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Exercise|OTHER: Repetitive magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Activated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: MILs|DRUG: Melphalan|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Gabapentin/B-complex|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eovist vs. Dotarem Healthy Volunteer MRI
Status: COMPLETED
Conditions: Transient Severe Arterial Phase Motion
Interventions: DRUG: gadoxetate disodium|DRUG: gadoterate dimeglumine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimized Diffusion-Weighted Imaging for the Evaluation of Post-Treatment Squamous Cell Carcinoma in the Neck: Comparative Study With FDG PET/CT
Status: TERMINATED
Conditions: Squamous Cell Carcinoma
Interventions: DEVICE: Diffusion-weighted imaging magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SDRM® vs. Collagen for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot|Ulcer Foot|Wound Heal
Interventions: PROCEDURE: Wound debridement|DEVICE: Wound closure matrix application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Excretion of Acetylamantadine by Cancer Patients
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Ingestion of a 200 mg dose of amantadine hydrochloride|DRUG: Ingestion of a 200 mg dose of amantadine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Chohort 1: Surufatinib|DRUG: Chohort 2: Immunotherapy|DRUG: Chohort 2: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Cytotoxic T Lymphocyte Immunotherapy Combination With PD-1 Inhibitor in the Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Second-line Treatment
Interventions: BIOLOGICAL: CTL|BIOLOGICAL: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Therapeutic Efficacy of CAR-T Cell Therapy in Patients With MDR-SRNS
Status: RECRUITING
Conditions: Multi-Drug Resistant Nephrotic Syndrome|CAR-T Cell Therapy
Interventions: BIOLOGICAL: anti-BCMA/CD70 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of a Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Undergoing Hemodialysis
Status: COMPLETED
Conditions: Influenza|End Stage Renal Failure|Chronic Kidney Disease
Interventions: BIOLOGICAL: Fluad|BIOLOGICAL: Agrippal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration|Age-Related Maculopathies|Age-Related Maculopathy|Maculopathies, Age-Related|Maculopathy, Age-Related|Retinal Degeneration|Retinal Neovascularization|Gene Therapy|Therapy, Gene|Eye Diseases
Interventions: BIOLOGICAL: AAV2-sFLT01|BIOLOGICAL: AAV2-sFLT01|BIOLOGICAL: AAV2-sFLT01|BIOLOGICAL: AAV2-sFLT01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatients' Knowledge About and Attitude Toward Randomised Clinical Trials
Status: COMPLETED
Conditions: Ambulatory Patients in the Dep. of Medical Gastroenterology|Ambulatory Patients in the Dep. of Gynecology|Ambulatory Patients in the Dep. of Orthopedic Surgery|Ambulatory Patients in the Dep. of Urology
Interventions: OTHER: Leaflet|OTHER: Brochure|OTHER: Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Efficacy Study of Prophylactic S. Pneumoniae Vaccine Following Challenge With S. Pneumoniae
Status: COMPLETED
Conditions: Pneumococcal Infections|Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: GEN-004 with Aluminum Hydroxide Adjuvant|BIOLOGICAL: Placebo|BIOLOGICAL: Streptococcus pneumoniae inoculation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth
Status: COMPLETED
Conditions: Prehypertension|Hypertension|Overweight and Obesity|Elevated Blood Pressure|Endothelial Dysfunction|Vascular Stiffness|Sleep
Interventions: DIAGNOSTIC_TEST: Cardiovascular Assessments|DIAGNOSTIC_TEST: Actigraphy|DIAGNOSTIC_TEST: Laboratory assessments|DIAGNOSTIC_TEST: Emotional/Behavioral Assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo-Controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of SXC-2023 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SXC-2023|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drainage Amount for Removal of Thoracostomy Tube
Status: COMPLETED
Conditions: Pneumothorax|Pleural Effusion
Interventions: OTHER: No drainage threshold|OTHER: Drainage <2 mL/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-center Clinical Evaluation of PC 1-Day vs 1-Day Acuvue Moist
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: omafilcon A|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, International, Follow-up Study to Monitor the Efficacy and Safety of the Occlutech® PmVSD Occluder in Patients With Perimembranous Ventricular Septal Defects
Status: ACTIVE_NOT_RECRUITING
Conditions: Perimembranous Ventricular Septal Defect
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Femoral Nerve Block Compared to Exparel in Total Knee Replacement
Status: UNKNOWN
Conditions: Osteoarthritis|Pain
Interventions: DRUG: Exparel|DRUG: Femoral Nerve Block Bupivacaine|DRUG: Toradol|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Biomarkers to Optimize Fluid Dosing,CRRT Initiation and Discontinuation in Pediatric ICU Patients With AKI
Status: TERMINATED
Conditions: Acute Kidney Injury|Fluid Overload
Interventions: OTHER: Continuous Renal Replacement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Effectiveness Study of a Candidate Vaginal Microbicide for Prevention of HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir gel|DRUG: Placebo (Universal HEC placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Intervention for Cardiovascular Disease
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: OTHER: control:usual medical management|BEHAVIORAL: intervention 1:usual medical management+individual dieting consultation|BEHAVIORAL: intervention 2:usual medical management+individual dieting consultation+ daily tea drinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence
Status: COMPLETED
Conditions: Substance Abuse|Cocaine Dependence
Interventions: DRUG: Placebo|DRUG: Bupropion XL|BEHAVIORAL: Abstinence Initiation|BEHAVIORAL: Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TL117 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: TL117|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing (MI) Intervention to Improve Adherence
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: BEHAVIORAL: Motivational interviewing intervention arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Meal Glycaemic Index and Exercise After Gastric Bypass
Status: COMPLETED
Conditions: Roux-en-Y Gastric Bypass|Obesity
Interventions: OTHER: Low GI mealtest|OTHER: Low GI mealtest and subsequent exercise|OTHER: High GI mealtest|OTHER: High GI mealtest and subsequent exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BETA Study: Improving Balance Function in Elderly by Progressive and Specific Training and Physical Activity
Status: UNKNOWN
Conditions: Elderly|Parkinsons Disease|Osteoporosis
Interventions: OTHER: Gait and balance group training|OTHER: Nordic walking (only osteoporosis group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Clinical Benefits of Dietary Supplement Quercetin for Managing Early Mild Symptoms of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: standard of care for COVID-19 as per the hospital guidelines|DIETARY_SUPPLEMENT: Quercetin Phytosome (QP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Low Oxygen Therapy and an Adenosine A2a Receptor Antagonist to Improve Functional Mobility After Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Myelopathy
Interventions: DRUG: Istradefylline|DEVICE: low oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intratumoral Injection of Recombinant Human Adenovirus Type 5 Combined With Tislelizumab and Lenvatinib in the Treatment of Advanced Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Recombinant Human Adenovirus Type 5|DRUG: Lenvatinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small-cell Lung Cancer (NSCLC)
Interventions: DRUG: Tislelizumab|DRUG: Pemetrexed (Non-squamous NSCLC) or Nab-paclitaxel(Squamous NSCLC)|DRUG: Carboplatin or Cisplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor and Cognitive Dual-task Gait Training Effect Functional Outcome in Intellectual Disability
Status: COMPLETED
Conditions: Intellectual Disability
Interventions: OTHER: Motor dual-task gait training|OTHER: Cognitive dual-task gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of taVNS of Brainstem Activation in Early and Late Parkinson's Disease Patients - an fMRI Study
Status: COMPLETED
Conditions: Parkinson Disease|Neurologic Disorder
Interventions: DEVICE: Noninvasive transcutaneous auricular vagus nerve stimulation at 100Hz|DEVICE: Noninvasive transcutaneous auricular vagus nerve stimulation at 25Hz|DEVICE: Sham cyma conchae stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adapting the Tumor Board Model for Mental Illness and Cancer
Status: RECRUITING
Conditions: Cancer|Severe Major Depression|Schizophrenia|Bipolar Disorder|Lung Cancer|Breast Cancer|Head and Neck Cancer|Gastrointestinal Cancer|Genitourinary Cancer
Interventions: BEHAVIORAL: Virtual Cancer and Mental Health Tumor Board
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Android Wear smartwatch|BEHAVIORAL: Adaptive Treatment|DRUG: Nicotine Patch|BEHAVIORAL: interviewing-based counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flexible Reinforced Laryngeal Mask Airway Versus Endotracheal Tube for Childhood Adenotonsillectomy
Status: COMPLETED
Conditions: Anesthesia Intubation Complication|Airway|Adenotonsillectomy|Children
Interventions: OTHER: Airway Management: Flexible Reinforced Laryngeal Mask Airway|OTHER: Airway Management: Endotracheal Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Oral Ixazomib in Adult Participants With Relapsed and/or Refractory (RR) Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: DRUG: Ixazomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting Balloon vs. Conventional Balloon in the Treatment of (re)Stenosis - a Randomized Prospective Study
Status: COMPLETED
Conditions: Peripheral Artery Occlusive Disease|Peripheral Artery Restenosis|Peripheral Artery Stenosis
Interventions: DEVICE: Conventional PTA|DEVICE: Drug-eluting balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sit Less, Interact, Move More (SLIMM) Regimen on Patients With Chronic Kidney Disease (CKD)
Status: TERMINATED
Conditions: Chronic Kidney Disease|End Stage Renal Disease
Interventions: BEHAVIORAL: SLIMM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MK-1972 in Human Immunodeficiency Virus (HIV)-1 Infected Participants Who Have Not Previously Received Antiretroviral Therapy (MK-1972-003)
Status: TERMINATED
Conditions: HIV-1 Infection
Interventions: DRUG: MK-1972|DRUG: Placebo to MK-1972
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers
Status: COMPLETED
Conditions: Malignant Lung Neoplasm
Interventions: PROCEDURE: Standard Follow-Up Care|OTHER: Caregiver-Related Intervention or Procedure|OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained Release In Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release 10mg|DRUG: Desvenlafaxine Succinate Sustained-Release 50 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT