pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus Genotype 1 - 6 Infection and Renal Impairment
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: Glecaprevir/pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Concerns of Cancer Patients Referred to Complementary Medicine Treatment Integrated Within Oncology Service
Status: RECRUITING
Conditions: Quality of Life
Interventions: OTHER: Complementary medicine consultation and treatment|OTHER: Patients receiving conventional supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aldesleukin in Participants With Metastatic Renal Cell Carcinoma or Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Metastatic Melanoma
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Nurture Intervention, A Group Model in Connecticut
Status: COMPLETED
Conditions: Behavior Problem|Development Delay|Emotional Disturbance|Family Conflict
Interventions: BEHAVIORAL: Family Nurture Intervention|BEHAVIORAL: Nutrition and Play Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy Patients (UC Davis)
Status: RECRUITING
Conditions: Speech Disorders|Speech Dysfunction|Laryngectomy; Status|Tracheoesophageal Prosthesis|Total Laryngectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Of Cabozantinib Treatment In Patients With Unresectable, Locally Advanced Or Metastatic Renal Cell Carcinoma Who Progressed After Previous Treatment With Checkpoint Inhibitors
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Renal Cell Carcinoma
Interventions: DRUG: Cabozantinib monotherapy|DRUG: All authorized TKI monotherapies in advanced RCC per FDA label in advanced RCC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Superb Microvascular Imaging in Focal Nodular Hyperplasia
Status: COMPLETED
Conditions: Focal Nodular Hyperplasia
Interventions: DRUG: Sonazoid|DEVICE: Superb-Microvascular imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B
Status: RECRUITING
Conditions: Hepatitis B|Chronic Hep B|HBV
Interventions: DRUG: APG-1387|DRUG: Entecavir 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-Up Study of Patients Who Have Undergone Surgery for Stage I, Stage II, or Stage III Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: OTHER: laboratory biomarker analysis|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of Inhaled HH-120 Aerosol in Healthy Volunteers
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection
Interventions: BIOLOGICAL: HH-120 Dose 1|BIOLOGICAL: HH-120 Dose 2|BIOLOGICAL: HH-120 Dose 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characteristics and Management of Postmenopausal Women With Osteoporosis Treated With Prolia® in France
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: AMG 162 - Prolia|DRUG: AMG 162 - Prolia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: neoadjuvant mFOLFIRINOX|DRUG: Stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: OTHER: Bilberry|OTHER: Blackcurrant|OTHER: Mango|OTHER: Beetroot|OTHER: Rose hip|OTHER: Glucose drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Can Probiotics be Used in the Prevention of Recurrent UTI in Paediatric Neurogenic Bladder
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: OTHER: Antibiotic|DRUG: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Huangqi Guizhi Wuwu Decoction in CKD Stage 2-4 Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathies
Interventions: DRUG: Huangqi Guizhi Wuwu decoction|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Anatomical Reduction and Functional Recovery Effects of Two Transvaginal Apical Slings on Pelvic Organ Prolapse
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Extraperitoneal high sacral ligament suspension surgery|PROCEDURE: Sacrospinous ligament fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: cleansing teeth after topical fluoride therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Therapy With Weekly Utidelone Combined With Cisplatin for Patients With Breast Cancer (NeoURANIA)
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: utidelone|DRUG: Cisplatin|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrates and Proteins 3h Before Surgery
Status: COMPLETED
Conditions: Surgery|Postoperative Complications|Inflammation
Interventions: DIETARY_SUPPLEMENT: Carbohydrate plus hydrolyzed protein beverage|OTHER: Preoperative fasting of 8h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol Value
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder|Alcohol Drinking
Interventions: BEHAVIORAL: Alcohol cue|BEHAVIORAL: Neutral cue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Delirium|Confusion|Sleep
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells
Status: RECRUITING
Conditions: Malignant Bone Tumor
Interventions: DRUG: narlumosbartmab plus doxorubicin、cisplatin、methotrexate、ifosfamide|DRUG: doxorubicin、cisplatin、methotrexate、ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraluminal Mono-antibiotic Therapy for Helicobacter Pylori Infection - A Comparison of Levofloxacin Powder and Levofloxacin Solution
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Levofloxacin film-coated tablet|DRUG: Levofloxacin intravenous solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Partial Response of Multiple Myeloma or Plasma Cell Leukemia|Plasma Cell Myeloma
Interventions: BIOLOGICAL: Incomplete Freund's Adjuvant|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Sargramostim|BIOLOGICAL: SVN53-67/M57-KLH Peptide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Durvalumab|RADIATION: Standard radiotherapy|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Doses (MAD) Study of PMG1015 in Idiopathic Pulmonary Fibrosis Subjects
Status: RECRUITING
Conditions: IPF
Interventions: DRUG: PMG1015|DRUG: PMG1015 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study Assessing Outcomes, Treatment Patterns and Related Costs in Patients in Bullous Pemphigoid
Status: COMPLETED
Conditions: Bullous Pemphigoid
Interventions: DRUG: treatment with topical superpotent corticosteroid therapy|DRUG: treatment with systemic therapy (methotrexate)|DRUG: treatment systemic therapy (prednisone)|DRUG: treatment with systemic therapy (prednisone)|DRUG: treatment with systemic therapy (doxycycline)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CABG Based on CT-FFR Versus Conventional Coronary Angiography
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Coronary artery bypass grafting based on conventional coronary angiography|PROCEDURE: Coronary artery bypass grafting based on cardiac computed tomography-derived fractional flow reserve.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: G-Pen Compared to Glucagen Hypokit for Severe Hypoglycemia Rescue in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Insulin Hypoglycemia|Type 1 Diabetes Mellitus|Severe Hypoglycemia
Interventions: DRUG: G-Pen|DRUG: Novo Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single-incision Laparoscopic Surgery in Acute Abdomen
Status: UNKNOWN
Conditions: Acute Appendicitis
Interventions: PROCEDURE: Hand-made glove setting|PROCEDURE: Commercialized single-incision multiport setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy
Status: COMPLETED
Conditions: Partial Seizures With or Without Secondary Generalization|Epilepsy
Interventions: DRUG: Placebo|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Opioids on Heart Rate During Rapid Sequence Intubation
Status: TERMINATED
Conditions: Rapid Sequence Induction
Interventions: DRUG: Remifentanil|DRUG: Sufentanil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Impact of Short-term Financial Incentives on Sexual Behavior and HIV Incidence in Lesotho
Status: UNKNOWN
Conditions: AIDS/HIV PROBLEM|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Financial incentive through lotteries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clonal Hematopoiesis in Ovarian Cancer Survivors and Risk of Secondary Blood Cancers, CHANCES Study
Status: RECRUITING
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Malignant Solid Neoplasm|Clonal Cytopenia of Undetermined Significance|Clonal Hematopoiesis|Idiopathic Cytopenia of Undetermined Significance|Non-Neoplastic Hematopoietic and Lymphoid Cell Disorder|Ovarian Carcinoma
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epidemiological Assessment of the Risk for Pancreatic Cancer Associated With the Use of Semaglutide in Patients With Type 2 Diabetes - A Cohort Study Based on Nordic Registry Data
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Ozempic®|DRUG: Active Comparator|DRUG: Rybelsus®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ivermectin Role in Covid-19 Clinical Trial
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: ivermectin|DRUG: hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Two Commercial Formulations of Botulinum Toxin Type A in the Treatment of Spasticity
Status: COMPLETED
Conditions: Spasticity
Interventions: DRUG: Botulinum toxin type A from laboratory Lanzhou|DRUG: Botulinum toxin type A from laboratory Allergan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MONOVISC Hip Osteoarthritis Study
Status: TERMINATED
Conditions: Osteoarthritis of the Hip
Interventions: DEVICE: MONOVISC|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of Rimonabant 5mg/Day or 20mg/Day Versus Placebo in Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery
Status: COMPLETED
Conditions: Neuromuscular Block, Residual
Interventions: DRUG: Neostigmine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of BIS-guided Propofol Induction on Hemodynamic Response in Patients With Cardiac Risk.
Status: UNKNOWN
Conditions: Anesthesia, General
Interventions: DRUG: Propofol|DEVICE: Bispectral Index Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ramadan Fasting in Secondary Adrenal Insufficiency Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Adrenal Insufficiency|Fasting, Intermittent
Interventions: BEHAVIORAL: education and drug adjustement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurocognitive and Neuroimaging Outcomes in Older Patients With Multiple Myeloma Treated With Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DIAGNOSTIC_TEST: Structural Image|DIAGNOSTIC_TEST: Functional Image|BEHAVIORAL: Digit Span subtest|BEHAVIORAL: Brief Test of Attention|BEHAVIORAL: Trail Making Test (Parts A & B)|BEHAVIORAL: Auditory Consonant Trigrams Test|BEHAVIORAL: Controlled Oral Word Association Test|BEHAVIORAL: Hopkins Verbal Learning Test-Revised|BEHAVIORAL: The Center for Epidemiological Study-Depression|BEHAVIORAL: The Functional Assessment of Chronic Illness Therapy-Fatigue Subscale, Version 4|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin And Pulmonary Artery Hemodynamics in Heart Failure With Reduced Ejection Fraction Patients With CardioMEMS®
Status: UNKNOWN
Conditions: Heart Failure, Systolic
Interventions: DRUG: Dapagliflozin|DEVICE: CardioMEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Therapy Preoperative Chemotherapy Versus Chemoradiotherapy in Locally Advanced Gall Bladder Cancers
Status: RECRUITING
Conditions: Gall Bladder Cancers
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|RADIATION: Chemoradiation|PROCEDURE: PETCECT|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Pharmacokinetic Study to Evaluate the Ability of a New Formulation to Enhance Curcuminoids Bioavailability
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: TG|DIETARY_SUPPLEMENT: STE|DIETARY_SUPPLEMENT: NOV|DIETARY_SUPPLEMENT: PHYT|DIETARY_SUPPLEMENT: TEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient and Caregiver Participation Through an Educational Health Information Technology System ("BMT Roadmap") in the Context of Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Patients Undergoing Bone Marrow Transplant (BMT)
Interventions: OTHER: BMT Roadmap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring
Status: RECRUITING
Conditions: Intraoperative Neurophysiological Monitoring|Magnesium Sulfate
Interventions: DRUG: Magnesium sulfate|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sitagliptin for Prevention of aGVHD After Alternative Donor Transplantation
Status: RECRUITING
Conditions: Acute-graft-versus-host Disease|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Sitagliptin + Standard Prophylaxis|DRUG: Standard Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of the Effects of 4 vs 3 Hours of Preoperative Fasting in Breast-feeding Infants
Status: COMPLETED
Conditions: Perioperative Complication
Interventions: OTHER: 3 hours of preoperative fasting for breast milk|OTHER: 4 hours of preoperative fasting for breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Neuropathy Caused by SORD Deficiency
Interventions: DRUG: AT-007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Versus Conventional Hospital Discharge Summaries and Prescriptions
Status: COMPLETED
Conditions: Patient Discharge|Continuity of Patient Care|Medical Records Systems, Computerized|Hospital Information Systems
Interventions: OTHER: Electronic discharge summary system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm
Status: WITHDRAWN
Conditions: Cerebral Vasospasm|Subarachnoid Hemorrhage
Interventions: DRUG: Sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients
Status: UNKNOWN
Conditions: Antifungal Agents|Invasive Fungal Infections|Mycoses|Acute-On-Chronic Liver Failure
Interventions: OTHER: Treatment strategy trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Paravertebral Block, Erector Spinae Plane Block, and in Combined Paravertebral-erector Spinae Block
Status: COMPLETED
Conditions: Pain, Postoperative|Thoracic Surgery, Video-Assisted|Thoracic Paravertebral Block|Erector Spinae Plane Block
Interventions: PROCEDURE: Two different block and combination of these two blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Genetics and Shared Decision Making in Improving Care for Patients With Stage IVA-C Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Activating ALK Gene Mutation Negative|Activating EGFR Gene Mutation Negative|Activating ROS1 Gene Mutation Negative|Health Care Provider|Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Counseling|OTHER: Questionnaire Administration|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Early Oral Stimulation on Reducing Cardiorespiratory Events and Transition to Oral Feeding in Preterm Infants
Status: COMPLETED
Conditions: Preterm Infants
Interventions: OTHER: no stimulation of the oral structure|OTHER: stimulation of the oral structure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dasatinib in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, Endometrial or Peritoneal Cancer
Status: TERMINATED
Conditions: Endometrial Clear Cell Adenocarcinoma|Ovarian Clear Cell Cystadenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Cancer
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zenith® Low Profile AAA Endovascular Graft
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms|Iliac Aneurysms|Aortoiliac Aneurysms
Interventions: DEVICE: Zenith Low Profile AAA Endovascular Graft and ancillary components
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Using Citrate to Replace Heparin in Babies Requiring Extracorporeal Membrane Oxygenation (ECMO)
Status: COMPLETED
Conditions: Heart Defects, Congenital|Respiratory Insufficiency
Interventions: DRUG: sodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medico-economic Evaluation Rehabilitation by Serious Games at Home for the Management of Patients With Parkinson's Disease Suffering From Gait and Balance Disorders
Status: NOT_YET_RECRUITING
Conditions: Patients With Parkinson's Disease
Interventions: DEVICE: play-based rehabilitaion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid
Status: RECRUITING
Conditions: Uterine Fibroids|D-chiro-inositol|Inositol|Epigallocatechin Gallate|Vitamin D|Vitamin B6
Interventions: DIETARY_SUPPLEMENT: Epigallocatechin gallate, Vitamin D, Vitamin B6, D-chiro-inositol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Influence on Oocyte Donation
Status: COMPLETED
Conditions: Disorder of Phosphate, Calcium and Vitamin D Metabolism|Female Infertility Due to Diminished Ovarian Reserve|Hormonal Requirement|Reproductive Disorder
Interventions: OTHER: vitamin D,AMH, AFC, reproductive outcome egg recipients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Opioid-free Anesthesia in VATS Lung Resection
Status: UNKNOWN
Conditions: Opioid Free Anesthesia
Interventions: PROCEDURE: Paravertebral block+Anterior serratus plane block|DRUG: opioid free anesthesia|DRUG: opioid based anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Manual Lymph Drainage in Fibromyalgia Patients
Status: ENROLLING_BY_INVITATION
Conditions: Fibromyalgia|Oxidative Stress
Interventions: COMBINATION_PRODUCT: conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Family's Adherence to Dental Care After DGA (HECC-CAN-study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries|Child Neglect
Interventions: OTHER: Social Paediatric Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia Areata
Status: TERMINATED
Conditions: Alopecia Areata
Interventions: DRUG: Deucravacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Lip, Oral Cavity and Pharynx|Larynx
Interventions: BIOLOGICAL: Nivolumab|DRUG: Tadalafil|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical Study
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: 0.5% cyclopentolate and 2.5% phenylephrine|DRUG: 0.5% tropicamide + 0.5% phenylephrine|DRUG: 0.5% tropicamide + 0.5% phenylephrine with a cotton wick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness Study of Integrative Treatment for Pediatric Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: OTHER: Fuxiong San|DRUG: Xiyanping injection|DRUG: Ribavirin Injection|DRUG: Xiaoer Qingfei Heji (mixture)|DRUG: Zhi Ke San|DRUG: Hua Tan San|DRUG: Guaifenesin Syrup|DRUG: Ibuprofen Suspension|DRUG: salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Intervention to Improve Memory in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class I
Interventions: BEHAVIORAL: Computerized Cognitive Training with Brain HQ|BEHAVIORAL: Computerized Crossword Puzzles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: RO5313534|DRUG: memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pioglitazone|DRUG: Acarbose|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Spacer Squale (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse
Status: UNKNOWN
Conditions: Intervertebral Disc Displacement
Interventions: DEVICE: Anterior cervical discectomy with prosthetic disc replacement / ESP.|DEVICE: Anterior cervical discectomy with prosthetic disc replacement / Squale.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided 5% Dextrose Injection for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Carpal Tunnel Hydrodissection with %5 dextrose in water injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isolated and Associated Effects of Physical Exercise and Estrogen Therapy on Climactercs Women
Status: COMPLETED
Conditions: Women's Health
Interventions: DRUG: Estradiol valerate|OTHER: Aerobic training|DRUG: Placebo|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prolonged Intravenous Infusion of β-lactam Antibiotics in Early Septic Patients
Status: UNKNOWN
Conditions: Sepsis
Interventions: BEHAVIORAL: prolonged intravenous infusion of β-lactams Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGLT2 Inhibitor Versus Sulfonylurea on Type 2 Diabetes With NAFLD
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Tofogliflozin|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Four or Six Weeks of Immobilization in the Conservative Treatment of Distal Radius Fractures in Elderly Population?
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Below elbow cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: dendritic cell-MART-1 peptide vaccine|BIOLOGICAL: gp100 antigen|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parental Health Decision-making for Children During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Stress|Coping Skills
Interventions: BEHAVIORAL: Positive imagination stimulation|BEHAVIORAL: Neutral recall message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tolerability, Acceptance, and Utility of Intermittent CGM Use in Youth With Prediabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: PreDiabetes|Obesity|Insulin Resistance
Interventions: DEVICE: Abbott Freestyle Libre 2|OTHER: Standard physical activity and nutritional counseling for prediabetes management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Self-Compassion Enhanced CBT vs. Standard CBT for Social Anxiety (SCE-CBT)
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Self-Compassion Enhanced Cognitive-Behavioral Therapy|BEHAVIORAL: Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: DRUG: dexamethasone|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of an Intensive Monitoring Strategy in Symptomatic Patients With Suspected Arrhythmia
Status: COMPLETED
Conditions: Suspected Arrhythmia
Interventions: OTHER: Intensive Monitoring Strategy: Reveal LINQ™ Insertable Cardiac Monitoring System".
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of CPAP on Biomarkers in Patients With OSA
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: AutoSet Spirit--Wash--Modified-AutoSet Spirit|DEVICE: Modified-AutoSet Spirit--Wash-AutoSet Spirit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Innovation for Standard Identification of Insertional HPV Mutations and of Target Therapeutic Genes in Cervical Cancer: Towards Development of Personalized Biomarkers in Clinical Oncology
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: PROCEDURE: Tumor biopsy|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nivolumab, Ipilimumab and Chemoradiation in Pancreatic Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Borderline Resectable, Locally Advanced or Metastatic Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DESWT-Pilot Study on the Safety of Myocardial Regeneration by Direct Epicardial Shock Wave Therapy in Combination With Coronary Artery Bypass Grafting
Status: UNKNOWN
Conditions: Reduced Left Ventricular Function Defined as LVEF < 50%|Regional Left Ventricular Wall Motion Abnormalities
Interventions: PROCEDURE: Direct Epicardial Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Pain Syndromes According to McGill's Method in Physiotherapy
Status: COMPLETED
Conditions: Vertebrogenic Pain Syndrome
Interventions: OTHER: Cervical pain|OTHER: Thoracic pain|OTHER: Lumbar pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Multi-Instillations of Apaziquone in Patients With Non-Muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: Apaziquone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Therapeutic Approach in Undernourished Maintenance Hemodialysis Patients (AMERICANO)
Status: UNKNOWN
Conditions: Chronic Kidney Failure
Interventions: OTHER: training on ergonomic bicycle|DRUG: Testosterone|DRUG: Oral nutritional supplementation|DRUG: n3 polyunsaturated fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: BIOLOGICAL: CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine|BIOLOGICAL: Sargramostim|PROCEDURE: Computed Tomography|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genes, Exercise, Neurocognitive and Neurodegeneration: Community-Based Approach
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Stretch exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor Versus High-dose Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After PCI
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Cerebrovascular Events in Patients With Occlusive Carotid Artery Disorders
Status: UNKNOWN
Conditions: Carotid Stenosis|Carotid Artery Plaque|Cerebrovascular Embolism and Thrombosis
Interventions: PROCEDURE: carotid endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Activity Levels, Inflammatory Markers, and Overall Wellness.
Status: COMPLETED
Conditions: Range of Motion
Interventions: DIETARY_SUPPLEMENT: Prickly pear juice|DIETARY_SUPPLEMENT: Pear-flavored juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Liraglutide in Improving Cardiac Function for Patients With Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ischemic Cardiomyopathy
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-tone External Muscle Stimulation for Pain Reduction
Status: COMPLETED
Conditions: Chronic Radicular Back Pain|Lumboischialgia|Cervico Brachialgia
Interventions: DEVICE: HTEMS|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Esophageal Sphincter (LES) Stimulation in Patients With Ineffective Esophageal Motility
Status: COMPLETED
Conditions: Quality of Life|Dysphagia|Electrical Stimulation of the Lower Esophageal Sphincter|Gastro Esophageal Reflux
Interventions: DEVICE: Electrical Stimulation of the Lower Esophageal Sphincter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AE05ML Device for ML Hem-o-lok Polymer Clip Delivery in Laparoscopic Surgical Procedures Observational Registery Study
Status: ENROLLING_BY_INVITATION
Conditions: Gall Bladder Disease|Bile Duct Diseases|Acute Cholecystitis|Kidney|Liver|Appendix|Spleen Disease|Prostate
Interventions: DEVICE: laparoscopic procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Biofeedback PFMT and Medication in Women With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solifenacin Succinate 5mg/tab daily|BEHAVIORAL: biofeedback-assisted pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Solanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability Study of Ramipril 10 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Ramipril 10 Capsule (Sandoz)|DRUG: Altace (Ramipril) 10 Capsule (Aventis Pharmaceutical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Unspecified, Adult
Interventions: DIAGNOSTIC_TEST: 68 Gallium -Fibroblast Activating Protein Inhibitor -46 Positron emission tomography / Computerized tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thiamin Deficiency in Obese Thai Children
Status: COMPLETED
Conditions: Obesity|Child|Thiamine Deficiency
Interventions: DRUG: Thiamine 1|OTHER: Non-thiamine|DRUG: Thiamine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Carfilzomib Consolidation Therapy After Autologous Stem Cell Transplantation (ASCT) for Mantle Cell Lymphoma (MCL), T-cell Lymphoma (TCL), and Diffuse Large B-Cell Lymphoma (DLBCL)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT in Chagas Disease Ventricular Tachycardia
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventricular Tachycardia|Chagas Disease|Cardiac Arrhythmia
Interventions: RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis|Cholecystectomy
Interventions: PROCEDURE: Laparoscopic cholecystectomy|PROCEDURE: Minilaparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Cervical Foley Catheter, Dinoprostone and a Combination of the Two for Labor Induction
Status: UNKNOWN
Conditions: Failed Medical or Unspecified Induction of Labor
Interventions: DEVICE: Foley catheter and pitocin|DEVICE: Foley catheter and Dinoprostone|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: DRUG: AVP-786|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IgM-Enriched Immunoglobulin for Neonatal Sepsis
Status: UNKNOWN
Conditions: Neonatal Sepsis, Early-Onset|Very Low Birth Weight Infant|Inflammation|Infant, Newborn, Disease
Interventions: DRUG: IgM-enriched IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor
Status: WITHDRAWN
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor|Rhabdoid Tumor of the Kidney
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p