pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cis-urocanic Acid (Cis-UCA) in Patients With Primary or Recurrent Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: DRUG: cis-UCA solution|DRUG: cis-UCA solution|DRUG: cis-UCA solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Inhaled Molgramostim in Cystic Fibrosis Subjects With Nontuberculous Mycobacterial Infection
Status: TERMINATED
Conditions: Mycobacterium Infections, Nontuberculous|Cystic Fibrosis (CF)
Interventions: DRUG: Molgramostim nebulizer solution|DEVICE: PARI eFlow nebulizer system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Huang-Lian-Jie-Du-Tang（HLJDT) on the Survival of Patients With Multiple Myeloma in Maintain Therapy
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide|DRUG: HLJDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.
Status: COMPLETED
Conditions: Disorders of Consciousness|Severe Brain Injury|Post-comatose Non-communicative Patients|Vegetative State|Minimally Conscious State
Interventions: DRUG: Analgesic administration|DRUG: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Beclomethasone Plus Prednisone in Treating Patients With Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: beclomethasone dipropionate|DRUG: methylprednisolone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: budesonide and montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
Status: RECRUITING
Conditions: Fetal Growth Retardation|Stillbirth and Fetal Death|Pregnancy Preterm
Interventions: OTHER: Placebo|DRUG: Melatonin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Resveratrol and Pharmacist Intervention on Diabetes Mellitus and Its Neuropathic Complication
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Resveratrol|DRUG: Placebo|OTHER: Resveratrol plus Pharmaceutical care|OTHER: Placebo+Pharmaceutical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines
Status: COMPLETED
Conditions: Lateral Canthus Rhytides|Crow's Feet Lines
Interventions: BIOLOGICAL: onabotulinumtoxinA|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)
Status: TERMINATED
Conditions: IgG4 Related Disease|IgG4-RD
Interventions: DRUG: elotuzumab|DRUG: placebo for elotuzumab|DRUG: methylprednisolone|DRUG: diphenhydramine|DRUG: acetaminophen|DRUG: famotidine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Drug-Drug Interaction Between Danoprevir/Low-Dose Ritonavir and Raltegravir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: raltegravir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Role of Antioxidant Supplementation in Keratoconus Patients
Status: WITHDRAWN
Conditions: Keratoconus
Interventions: OTHER: Antioxidants (Vitamins A,C,E) plus GSH|OTHER: Placebo|DIETARY_SUPPLEMENT: Centrum|COMBINATION_PRODUCT: Dietary Sources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Creams With or Without Urea Influence the Hydration of the Skin of the Foot
Status: COMPLETED
Conditions: FOOT
Interventions: OTHER: pre- Hydratión skin|OTHER: post- Hydratión skin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Schistosomiasis Diagnosis Using a CAA Antigen Test
Status: UNKNOWN
Conditions: Schistosomiasis Hematobium|Diagnostic|Drug Reaction|Pregnancy
Interventions: DRUG: Praziquantel|DIAGNOSTIC_TEST: UCP-LF CAA|DIAGNOSTIC_TEST: composite diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiotherapy and Therapeutic Education After Total Knee Arthroplasty.
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Usual care|OTHER: PNE + CST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symbicort in Asthmatic Children - SEEDLING
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol|DRUG: budesonide|DRUG: formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Genicular Nerve Block for Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Genicular nerve Block|PROCEDURE: Local Infiltration Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Malaria
Interventions: DRUG: M5717 330 mg|DRUG: M5717 500 mg|DRUG: M5717 660 mg|DRUG: Pyronaridine 360 mg|DRUG: Pyronaridine 360 mg|DRUG: Pyronaridine 540 mg|DRUG: Pyronaridine 720 mg|DRUG: Pyronaridine-artesunate (Pyramax) 360 mg/120 mg|DRUG: Pyronaridine- artesunate (Pyramax) 540 mg/180 mg|DRUG: Pyronaridine-artesunate (Pyramax) 720 mg/240 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Oral Etoposide|DRUG: Oral 9-Nitrocamptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Multicenter Study of Carfilzomib With Lenalidomide and Dexamethasone in Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Tolerability of the SkinPen on Male and Female Subjects' Dorsal Hands as a Treatment for Signs of Hand Aging
Status: WITHDRAWN
Conditions: Aging
Interventions: DEVICE: SkinPen Precision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Autologous mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care
Status: RECRUITING
Conditions: Diabetes|Bariatric Surgery|Metformin
Interventions: DRUG: Metformin|OTHER: Standard Care|DIETARY_SUPPLEMENT: Standardized meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Once-Monthly Intravenous Mircera in Hemodialysis Patients With Chronic Renal Anemia.
Status: WITHDRAWN
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zika and Neurodevelopment Among Infants in Grenada
Status: COMPLETED
Conditions: Zika Virus Infection|Neurocognitive Deficit|Development, Child|Neurodevelopmental Abnormality
Interventions: BEHAVIORAL: Conscious Discipline-Based Environmental Enrichment Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Profile and Prognosis of Malignant Liver Tumors With Radiofrequency Ablation (RFA) Therapy
Status: COMPLETED
Conditions: Liver Cancer
Interventions: BIOLOGICAL: immunotherapy with Nivolumab|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DERIVO® 2heal® Study: Clinical Safety and Efficacy of the DERIVO® 2heal® Embolisation Device
Status: RECRUITING
Conditions: Intracranial Aneurysm|Flow Diverter
Interventions: DEVICE: Flow Diverter Treatment with DERIVO 2 Heal Embolisation Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease Moderate|Chronic Obstructive Pulmonary Disease Severe|Acute Exacerbation of COPD
Interventions: DEVICE: Neuromuscular Electrical Nerve Stimulation|OTHER: Usual Physiotherapy treatment (Chest Physiotherapy and mobility)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Antroquinonol capsule 100mg|DRUG: Antroquinonol capsule 200mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps
Status: COMPLETED
Conditions: Polyp of Large Intestine
Interventions: PROCEDURE: Cold biopsy polypectomy|PROCEDURE: Cold snare polypectomy|DEVICE: Cold snare polypectomy|DEVICE: Cold biopsy polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: placebo|DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Microbiome is Associated With the Response to Chemoradiotherapy in Initial Inoperable Patients With Esophageal Squamous Cell Cancer
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Chemoradiotherapy|Initial Inoperable
Interventions: OTHER: regular chemoradiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extension of Study TKT024 Evaluating Long-Term Safety and Clinical Outcomes in MPS II Patients Receiving Idursulfase
Status: COMPLETED
Conditions: Hunter Syndrome|Mucopolysaccharidosis II (MPS II)
Interventions: BIOLOGICAL: Idursulfase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
Status: COMPLETED
Conditions: Internal Derangement of Knee
Interventions: DRUG: 0.25% Bupivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Versus CT Guided Celiac Plexus Neurolysis in Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pain, Chronic
Interventions: PROCEDURE: Intraoperative celiac plexus neurolysis|PROCEDURE: CT guided celiac plexus neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM
Status: NOT_YET_RECRUITING
Conditions: Waldenstrom Macroglobulinemia
Interventions: DRUG: Zanubrutinib|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activated Autologous T Cells Against Glioma Cancer Stem Cell Antigens for Patients With Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: BIOLOGICAL: Activated T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Peritoneal Carcinomatosis
Interventions: DRUG: Cisplatin|DRUG: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Mitomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Tourniquet Release Times in Bunion Surgery
Status: UNKNOWN
Conditions: Hallux Valgus|Hallux Rigidus
Interventions: OTHER: Standard care|OTHER: Tourniquet release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Invasive Carcinoma of the Breast|Breast Cancer|Node Negative Breast Cancer|Micrometastasis Breast Cancer|Hormone Receptor Positive Breast Cancer
Interventions: COMBINATION_PRODUCT: Pertuzumab+TRASTUZUMAB|DRUG: ADJUVANT ENDOCRINE THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Advagraf® Switching From Cyclosporine Between the Group That Was Treated With a 50% Reduced Corticosteroid and the Group With Maintained Corticosteroid for Stable Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Advagraf|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-inflammatory Diet in Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Anti-inflammatory Diet|OTHER: Healthy Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Probiotics for NSAID-induced Enteropathy in Arthritis Patients
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis
Interventions: COMBINATION_PRODUCT: Probiotics capsule|COMBINATION_PRODUCT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: CAT-2054|DRUG: Placebo|DRUG: CAT-2054-C|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Cardiovascular Disease|Coronary Artery Disease
Interventions: PROCEDURE: saphenous vein graft|PROCEDURE: radial artery graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leg Amputation and Continuous Sciatic Nerve Block
Status: TERMINATED
Conditions: Phantom Limb|Leg Amputation
Interventions: DRUG: ropivacaine/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: 4 mg elamipretide|DRUG: 40 mg elamipretide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids
Status: COMPLETED
Conditions: Barrett's Esophagus|Obesity
Interventions: DRUG: Omega-3 polyunsaturated fatty acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Mosunetuzumab|DRUG: Polatuzumab vedotin|DRUG: Tocilizumab|DRUG: Rituximab|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Rising Doses of APO010 in Relapsed/Refractory Multiple Myeloma Patients Selected by DRP
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: APO010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Diffusion MRI for Staging, Response Prediction and Detecting Tumor Recurrence in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Carcinoma
Interventions: OTHER: Whole body diffusion-weighted MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP)
Status: COMPLETED
Conditions: Infection Resistant to Multiple Drugs
Interventions: OTHER: TDM, Monitoring of Neuro-and Nephropathology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis
Status: TERMINATED
Conditions: Advanced Cancers
Interventions: OTHER: Placebo|DRUG: Glutamine|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Systemic Disposition of ASP1585 After Administration of 14C-labeled Drug
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP1585
Interventions: DRUG: ASP1585|DRUG: 14C-Labeled ASP1585
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Kinesio-taping Versus Pelvic Floor Exercise for Post Colonoscopy Coccydynia
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: kinesio-taping techniques.|OTHER: Pelvic floor exercise|OTHER: traditional physical therapy program , stretching of piriformis. iliopsoas, clam shell exercise,seat cushioning and seat kitz.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency vs Dry Needling in Myofascial Pain
Status: NOT_YET_RECRUITING
Conditions: Myofascial Pain
Interventions: PROCEDURE: pulsed radiofrequency|PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement to Perform Thoracocentesis After a Specific Training in Medical Students With the Supervised Use of an Augmented Reality Simulator
Status: NOT_YET_RECRUITING
Conditions: Pleural Effusion|Frist Time Indication to Perform a Thoracentesis|Medical Student Training
Interventions: OTHER: Simulation group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modification Of Disease Outcome In COPD
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: fluticasone 500 mcg|DRUG: fluticasone 500 mcg + salmeterol 50 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Plus Docetaxel in Chemotherapy-Refractory/Resistant Patients With Advanced Non-Small-Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: Nimotuzumab and Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
Status: NOT_YET_RECRUITING
Conditions: Leukemia
Interventions: DRUG: Quizartinib|DRUG: Placebo|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo Followed by a Voluntary Open Label Extension for Safety.
Status: COMPLETED
Conditions: Arthralgia|Bunion|Hallux Valgus|Pain Assessment|Tapentadol
Interventions: DRUG: CG5503 IR;tapentadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: SLC-3010|COMBINATION_PRODUCT: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Reduction to Reach Elimination of Trachoma B
Status: NOT_YET_RECRUITING
Conditions: Trachoma
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Chronic Postsurgical Pain in Adults
Status: COMPLETED
Conditions: Chronic Postsurgical Pain|Acute Post Operative Pain
Interventions: PROCEDURE: Cardiothoracic surgery|PROCEDURE: Breast surgery|PROCEDURE: Gastrointestinal surgery|PROCEDURE: Genitourinary surgery|PROCEDURE: Orthopaedic surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cap-assisted Water Immersion Versus Water Immersion Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DEVICE: soft straight distal cap D-201-14304 Olympus attached to the tip of the colonoscope|PROCEDURE: water immersion colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of the RHEA Vital Sign Vigilance System in Hospital Patients Patients
Status: COMPLETED
Conditions: Vital Sign Monitoring
Interventions: DEVICE: Investigational Group|DEVICE: reference group-Earlysense system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety of PCI-32765 in Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Clinical Trial of KAD-1229 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: KAD-1229|DRUG: Placebo|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Intermittent Catheterization Versus Trial Without Catheter
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: intermittent catheterization|PROCEDURE: trial without catheter|DRUG: alpha-blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices
Status: RECRUITING
Conditions: Intracranial Aneurysm|Brain Aneurysm|Unruptured Cerebral Aneurysm|Ruptured Cerebral Aneurysm|Cerebral Aneurysm
Interventions: PROCEDURE: surgical clipping, simple coiling, high-porosity stenting with/ without coiling, intra-arterial flow diversion with/ without coiling|DEVICE: WEB embolization device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of the Efficacy and Tolerability of Depakote ER and Depakote DR
Status: COMPLETED
Conditions: Mania|Mixed Mania
Interventions: DRUG: Depakote ER|DRUG: Depakote DR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics as Supplement to Non-surgical Periodontal Treatment
Status: RECRUITING
Conditions: Periodontitis
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-center, Randomized, Blinded Study to Evaluate Durasphere FI for the Treatment of Fecal Incontinence
Status: TERMINATED
Conditions: Fecal Incontinence
Interventions: DEVICE: Durasphere FI|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR
Status: ACTIVE_NOT_RECRUITING
Conditions: Rhegmatogenous Retinal Detachment|Proliferative Vitreoretinopathy
Interventions: DRUG: Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA]|DRUG: Glycerin 0.2%/Hypromellose 0.2%/Peg 1%/Soln,Oph,Ud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours
Status: RECRUITING
Conditions: Melanoma|Head and Neck Squamous Cell Carcinoma|Pancreatic Ductal Adenocarcinoma|Colorectal Cancer|Solid Tumor
Interventions: DRUG: IPN01194|DRUG: IPN01194
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PK and PD Interaction Between YH4808, Amoxicillin and Clarithromycin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: YH4808|DRUG: Nexium|DRUG: Amoxicillin|DRUG: clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase III Study of Dasatinib vs Imatinib in Patients With Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Myeloid Leukemia, Chronic
Interventions: DRUG: Dasatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thimble Mindfulness App and Recovery Patch Descriptions
Status: NOT_YET_RECRUITING
Conditions: Needle Fear|Vaccine Hesitancy
Interventions: DEVICE: Thimble Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Ocular Electroacupuncture on Oculomotor Nerve Palsy
Status: UNKNOWN
Conditions: Oculomotor Nerve Palsy
Interventions: OTHER: ocular electroacupuncture|OTHER: ocular acupuncture|OTHER: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Multi-center, Prospective, Randomized, Double-blind, Placebo- Controlled Study to Evaluate the Effectiveness and Safety of ZP5-9676 for the Treatment of Soil Transmitted Helminthiasis (STH)
Status: NOT_YET_RECRUITING
Conditions: Soil-Transmitted Helminthiasis (STH)
Interventions: DRUG: ZP5-9676 600 mg dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training in Patients With MCI Using fMRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Memory Training|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Alphabet search
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prospective Study of TW in Treatment of IgAN With Asymptomatic Abnormal Urinalysis
Status: TERMINATED
Conditions: IgA Nephropathy
Interventions: DRUG: tripterygium wilfordii (TW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EcoAnaesthesia Facemask Versus Standard Facemask During Anesthesia Induction
Status: WITHDRAWN
Conditions: Anesthesia Induction
Interventions: DEVICE: EcoAnaesthesia facemask first|DEVICE: Portex Adult (Standard) facemask first|DEVICE: Portex Adult (Standard) facemask second|DEVICE: EcoAnesthesia facemask second
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: IDH1 Peptide Vaccine for Recurrent Grade II Glioma
Status: COMPLETED
Conditions: Brain Cancer|Brain Neoplasm, Primary|Brain Neoplasms, Recurrent|Brain Tumor|Cancer of the Brain
Interventions: BIOLOGICAL: PEPIDH1M vaccine|BIOLOGICAL: Tetanus-Diphtheria Toxoid (Td)|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Spontaneous Cortical Activity by tDCS: BRAIN Initiative I
Status: COMPLETED
Conditions: Brain Function
Interventions: DEVICE: transcranial direct-current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.
Status: COMPLETED
Conditions: Anesthesia, Local|Analgesia|Arthropathy of Hip
Interventions: OTHER: Opioid and non opioid postoperative analgesia.|OTHER: Fascia iliaca compartment block|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC)
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Aprepitant|DRUG: Aprepitant Placebo|DRUG: Ondansetron|DRUG: Dexamethasone|DRUG: Ondansetron Placebo|DRUG: Rescue Therapy (granisetron, dolasetron, tropisetron or ondansetron; metoclopramide or alizapride).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of VAC-3S Therapeutic Properties When Combined With Standard ART in the Course of HIV-1 Infection
Status: UNKNOWN
Conditions: HIV
Interventions: BIOLOGICAL: VAC-3S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Pain Chronic
Interventions: PROCEDURE: Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Advancing Symptom Alleviation With Palliative Treatment
Status: COMPLETED
Conditions: Heart Failure|Pulmonary Disease, Chronic Obstructive|Emphysema|Pulmonary Fibrosis, Interstitial Lung Disease
Interventions: BEHAVIORAL: ADAPT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fecal Microbiota Transplantation for Pancreatitis With Infectious Complications(FMTPIC)
Status: UNKNOWN
Conditions: Acute Pancreatitis|Fecal Microbiota Transplantation|Bacterial Translocation|Infectious Complications
Interventions: PROCEDURE: Fecal Microbiota Transplantation|DRUG: The traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Fluticasone Furoate (FF)/Umeclidinium(UMEC)/Vilanterol (VI) in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/UMEC/VI|DEVICE: ELLIPTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase
Status: COMPLETED
Conditions: Gaucher Disease
Interventions: BIOLOGICAL: GA-GCB (velaglucerase alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Study of Linperlisib Plus CHOP Versus CHOP in Patients With Newly Diagnosed Peripheral T Cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: Linperlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-alcoholic Fatty Liver Disease|Fatty Liver, Nonalcoholic|NAFLD|Nonalcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: Efinopegdutide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Near Infrared Spectroscopy of Kidney for Prediction of Acute and Sub-acute Kidney Injury in Partial Nephrectomy
Status: UNKNOWN
Conditions: Kidney Injury
Interventions: DEVICE: near infrared spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Assessment Study of Steroid Effect in Relapsing Multiple Sclerosis Subjects Treated With Glatiramer Acetate
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Radiotherapy With CAR-T Cells in the Treatment of Relapsed and Refractory Hematological Malignancies With Extramedullary Lesions
Status: RECRUITING
Conditions: Hematological Malignancies
Interventions: DRUG: CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEsenchymal StEm Cells for Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: Mesenchymal stem cells|DRUG: Suspension media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Oral Potassium Citrate on the Prevention of Nephrocalcinosis in Extreme Premature
Status: UNKNOWN
Conditions: Nephrocalcinosis
Interventions: DRUG: Potassium Citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Monitoring in Intensive Care Unit of Neuromuscular Blocking Agents Used for Acute Respiratory Distress Syndrome After Cardiothoracic Surgery
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Train of four monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases
Status: COMPLETED
Conditions: Bone Neoplasms
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Soft Tissue Stability in Immediate Implant Placement Using (VST) Versus Conventional Flap in Type II Extraction Sockets
Status: ACTIVE_NOT_RECRUITING
Conditions: Badly Broken Tooth in a Socket Type II Eligible to be Replaced by Immediate Implant
Interventions: PROCEDURE: Vestibular socket therapy|PROCEDURE: conventional full thickness flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Bioequivalence of Loratadine Oral Solution/Syrup Versus Claritin Peach Syrup
Status: COMPLETED
Conditions: Histamine H1 Antagonists, Non-Sedating
Interventions: DRUG: Loratadine oral solution|DRUG: Loratadine (Claritin peach syrup)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Light Intensity Bleaching Versus Descending Light Intensities Bleaching on Post Bleaching Teeth Sensitivity
Status: COMPLETED
Conditions: Discoloured Teeth
Interventions: DEVICE: Philips Zoom! White Speed whitening lamp|DEVICE: Philips Zoom! Advanced power whitening lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravenous Azithromycin Plus Intravenous Ceftriaxone Followed by Oral Azithromycin With Intravenous Levofloxacin Followed by Oral Levofloxacin for the Treatment of Moderate to Severely Ill Hospitalized Patients With Community Acquired Pneumonia
Status: COMPLETED
Conditions: Community-Acquired Pneumonia (CAP)
Interventions: DRUG: IV azithromycin|DRUG: ceftriaxone|DRUG: oral azithromycin|DRUG: IV levofloxacin|DRUG: oral levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Optimization of Indocyanine Green Administration in NIRF-C During L.Cholecystectomy.
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: VERDYE powder for solution for injection 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of "Rongyang Zhengyifang" Tea Bag With COVID-19 Variant Virus
Status: ENROLLING_BY_INVITATION
Conditions: Herbal Interaction
Interventions: OTHER: Rong-Yang Zhengyifang" tea bag|OTHER: placebo tea bag
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spectral Analysis of Central Venous Pressure Waveform
Status: COMPLETED
Conditions: Donor Hepatectomy|Central Venous Catheter|Hypovolemia
Interventions: PROCEDURE: Placement of a central venous catheter|DEVICE: Monitoring of central venous pressure|DRUG: Furosemide-induced hypovolemia before graft procurement|DRUG: Replacement of fluid loss after graft procurement|DEVICE: Monitoring of stroke volume variation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Generic Pegfilgrastim vs Brand Name Pegfilrastim for Neutrophil Recovery After Autotransplant
Status: COMPLETED
Conditions: Myeloma Multiple|Lymphoma
Interventions: DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing of the Pharmacokinetic, Safety and Pharmacodynamic of QL1206 and Xgeva® in Healthy Adults
Status: COMPLETED
Conditions: Healthy People
Interventions: DRUG: QL1206|DRUG: Xgeva®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Gather Information About the Use of Healthcare Services and the Way the Disease is Cared for in Canadian Patients With Prostate Gland Cancer Which Spread Throughout the Body
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy?
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy; Syndrome, Seizures of Localized Onset
Interventions: DIAGNOSTIC_TEST: electroencephalogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instillation of Gentamicin and Dexamethasone in Bronchiectasis Compared to Conventional Treatment
Status: RECRUITING
Conditions: Bronchiectasis With Acute Exacerbation
Interventions: DRUG: bronchoscopic airway clearance followed by local instillation of gentamicin and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Placebo|DRUG: ipratropium bromide|DRUG: salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Drotaverine in Dysmenorrhoea Treatment
Status: TERMINATED
Conditions: Dysmenorrhea
Interventions: DRUG: Drotaverine|DRUG: Drotaverine Placebo|DRUG: Ibuprofen|DRUG: Ibuprofen Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT