pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Erectile Dysfunction
Interventions: BIOLOGICAL: Platelet-Rich-Plasma|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LINO-1713 in Healthy Korean Female Subjects
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: LINO-1713 1 tablet|DRUG: LINO-1713 once a day for 24 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon Alpha Lozenges Plus Oseltamivir for Influenza Treatment
Status: COMPLETED
Conditions: Influenza A Virus Infection
Interventions: DRUG: Interferon-alpha|DRUG: Oseltamivir|OTHER: maltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Allocetra by Intra-articular Injection for the Treatment of Psoriatic Arthritis
Status: NOT_YET_RECRUITING
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Allocetra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) in the Treatment of Myelofibrosis With Myeloid Metaplasia
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: Obatoclax mesylate (GX15-070MS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Bioavailability From Fortified Food
Status: COMPLETED
Conditions: Iron Bioavailability
Interventions: OTHER: Labeled iron salt Fe54|OTHER: Labeled iron salt Fe57|OTHER: Labeled iron salt Fe58
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation
Status: UNKNOWN
Conditions: Crohn's Disease|Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Obeticholic Acid in Morbidly Obese Patients and Healthy Volunteers
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Obeticholic acid|DRUG: Obeticholic acid placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Overactive Bladder Syndrome: Incobotulinumtoxin Versus Onabotulinumtoxin
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: IncobotulinumtoxinA 100 UNT Injection [Xeomin]|DRUG: OnabotulinumtoxinA 100 UNT [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Multiple Myeloma|Advanced Solid Tumors
Interventions: DRUG: Palbociclib|DRUG: Sunitinib|DRUG: Temsirolimus|DRUG: Trastuzumab and Pertuzumab|DRUG: Vemurafenib and Cobimetinib|DRUG: Regorafenib|DRUG: Olaparib|DRUG: Pembrolizumab|DRUG: Nivolumab and Ipilimumab|DRUG: Abemaciclib|DRUG: Talazoparib|DRUG: Atezolizumab and PHESGO|DRUG: Atezolizumab and Talazoparib|DRUG: Entrectinib|DRUG: Larotrectinib|DRUG: Tucatinib plus Trastuzumab Subcutaneous (SC)|DRUG: Futibatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of NAC on Symptoms of CHR Patients
Status: RECRUITING
Conditions: Prodromal Schizophrenia
Interventions: DIETARY_SUPPLEMENT: N-Acetylcysteine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Primary Myelofibrosis|Thrombocytopenia
Interventions: DRUG: Eltrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics of Emtricitabine/Tenofovir/Efavirenz in HIV-infected Patients With Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: Emtricitabine/tenofovir/efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Different Training Modes (Intense Versus Ordinary) on the Immune System and Memory Functions in pwMS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Intensive Training|BEHAVIORAL: Normal Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Local Infiltration Technique in Adult Tonsillectomy
Status: SUSPENDED
Conditions: Post Operative Pain
Interventions: OTHER: Infiltration|OTHER: Placebo|OTHER: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of the French Version if the Metagognitive Bibliotherapy Program "MYMCT" on Obsessive-compulsive Symptoms
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: MyMCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Collect Calibration & Performance Data of the KBS Systems 1.0 Non-Invasive Glucose Monitoring Device
Status: UNKNOWN
Conditions: Diabetes
Interventions: DEVICE: Spectroscopy for Analyte Quantification
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: iobenguane I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
Status: RECRUITING
Conditions: Metabolism|Trauma|Nutritional Deficiency|Protein Malnutrition|Gastroparesis|Muscle Loss|Calorie Malnutrition Protein
Interventions: OTHER: Medical food
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of TTI-101 in Participants With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: TTI-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response of a 2-dose Regimen of rDEN1delta30 Dengue Virus Vaccine
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: rDEN1delta30|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Omega-3 as an Adjunct to Non-Surgical Periodontal Therapy on Chemerin Level in Periodontitis Patients With Diabetes: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Diabetes Mellitus|Periodontal Diseases
Interventions: DRUG: Omega 3|PROCEDURE: SRP alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patterns of Glaucoma in Glaucoma Subspecialty Clinics in Egypt and India in the Year 2018
Status: UNKNOWN
Conditions: Determining Patterns of Glaucoma in Glaucoma Sub-specialty Clinics in Two Countries: Egypt and India
Interventions: OTHER: collection of data from patient files
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SOLX Titanium Sapphire Laser for Trabeculoplasty
Status: COMPLETED
Conditions: Glaucoma|Glaucoma, Open Angle
Interventions: DEVICE: SOLX Titanium Sapphire Laser (TiSaLT)|DEVICE: Argon Laser Trabeculoplasty (ALT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 1540 Nanometer Erbium Glass Laser to Improve Benign Dermatofibromas
Status: COMPLETED
Conditions: Dermatofibroma of Skin
Interventions: DEVICE: 1540 nanometer Erbium glass laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Safety and Pharmacokinetics of VM-1500 After Multiple Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: HIV-infection
Interventions: DRUG: VM-1500|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Web-based Intervention for Guardians of Children Whose One Parent Has Murdered the Other
Status: WITHDRAWN
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Interactive Healthcare Communication Application|BEHAVIORAL: Control Web sites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ZG005 in Combination With Paclitaxel＋Platinum-based ± Bevacizumab in Patients With Advanced Cervical Carcinoma
Status: RECRUITING
Conditions: Cervical Carcinoma
Interventions: DRUG: ZG005 Powder for Injection|DRUG: Paclitaxel|BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Lumen-apposing Metal Stent and Double-pigtail Plastic Stents for Treatment of Walled-off Necrosis
Status: COMPLETED
Conditions: Walled-off Necrosis
Interventions: PROCEDURE: endoscopic ultrasound|DEVICE: lumen-apposing metal stent|DEVICE: double-pigtail plastic stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Apatinib in Heavily Pretreated Advanced Non-squamous Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: apatinib single agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Eating Disorders by Physical Activity and Nutrition Counseling
Status: COMPLETED
Conditions: Bulimia Nervosa|Binge Eating Disorder
Interventions: BEHAVIORAL: Cognitive Behaviour Therapy|BEHAVIORAL: Physical Activity and Dietary Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of CV-MG01 (Myasterix) in Myasthenia Gravis
Status: WITHDRAWN
Conditions: Myasthenia Gravis, Generalized
Interventions: BIOLOGICAL: CV-MG01|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: Gepotidacin RC Tablet|DRUG: Gepotidacin HSWG Tablet|DRUG: Gepotidacin Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining and Comparing the Temporal Changes and Results of Cosmetic, Quality of Life and Patient Satisfaction Achieved With Immediate and Delayed-immediate Implant-based Breast Reconstruction Procedures and Contralateral Symmetrization Techniques
Status: RECRUITING
Conditions: Mastectomy; Lymphedema|Breast Cancer|Quality of Life
Interventions: PROCEDURE: A: expander-silicone implant exchange and contralateral symmetrization with mastopexy and if needed with volume reduction|PROCEDURE: B: expander-silicone implant exchange with contralateral symmetrization with mastopexy and Ultrapro sling|PROCEDURE: C: expander-silicone implant exchange and contralateral symmetrization with mastopexy and silicone implant augmentation|PROCEDURE: D: expander-silicone implant exchange and contralateral symmetrization with mastopexy and Utrapro sling and silicone implant augmentation|PROCEDURE: E: unilateral simple mastectomy|PROCEDURE: F: after bilateral SSM, ASM, NSM, expander-implant exchange
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: imatinib mesylate|DRUG: imatinib|DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Finding the Best Combination of Brain and Spinal Cord Stimulation With Hand Training After Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: Synaptic Pairing Interval|PROCEDURE: Frequency|PROCEDURE: Bouts|PROCEDURE: Spacing|PROCEDURE: Exercise|PROCEDURE: SCAP plus Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Surveillance for ADACEL™ in South Korea
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: ADACEL™:Adsorbed Diphtheria, Tetanus Toxoids and Component Pertussis Combined
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Fentanyl-Propofol-EMLA of L.M.X4 Technique for Bone Marrow Aspiration
Status: TERMINATED
Conditions: Bone Marrow Disease|Pain
Interventions: DRUG: Fentanyl|DRUG: EMLA|DRUG: L.M.X4|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ascorbic Acid Treatment in CMT1A Trial (AATIC)
Status: COMPLETED
Conditions: Charcot-Marie-Tooth Disease|Hereditary Motor and Sensory Neuropathies
Interventions: DRUG: Placebo|DRUG: ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: AV-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Fulvestrant|DRUG: Placebo|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Reverse hybrid therapy|DRUG: Standard triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inulin and Nitrate's Effects on Vascular Health and Gut Microbiome
Status: ACTIVE_NOT_RECRUITING
Conditions: Endothelial Dysfunction|High Blood Pressure|Gut Microbiota Dysbiosis and Nutrition
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Potassium nitrate and inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis
Status: RECRUITING
Conditions: Psychosis Nos/Other
Interventions: BEHAVIORAL: Brief family engagement intervention for CHR|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CT-388 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: CT-388|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Vascular Biology of Dipyridamole in Peripheral Arterial Disease (PAD)
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Dipyridamole 200mg and Aspirin 25mg bid:|DRUG: Dipyridamole 200 mg bid|DRUG: Aspirin 25 mg bid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EndoTAG-1+GEM vs GEM in Patients With Locally Advanced/Metastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOX
Status: COMPLETED
Conditions: Metastatic Pancreas Cancer|Locally Advanced Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: DRUG: EndoTAG-1|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: 0.25% AR-12286 / 0.004% travoprost|DRUG: 0.5% AR-12286, 0.004% travoprost|DRUG: 0.004% Travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Gemcitabine Hydrochloride or Gemcitabine Hydrochloride Alone in Treating Patients With Pancreatic Cancer Previously Treated With Surgery
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer|Stage III Pancreatic Cancer
Interventions: DRUG: dasatinib|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|GENETIC: mutation analysis|GENETIC: nucleic acid sequencing|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study Followed by a Safety and Efficacy Study for Patients With Multiple Myeloma or Lymphoma
Status: TERMINATED
Conditions: Multiple Myeloma|NonHodgkin Lymphoma
Interventions: DRUG: TAS4464
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCR Reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL
Status: RECRUITING
Conditions: Acute Lymphocytic Leukemia
Interventions: BIOLOGICAL: TCR reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T cell|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RADIANCE Continued Access Protocol
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension|Hypertension, Resistant to Conventional Therapy|Vascular Diseases|Cardiovascular Diseases
Interventions: DEVICE: Renal Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: DRUG: 18F-FSPG|DRUG: 11C-Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Smart-phone Health Coaching Intervention to Promote Maintenance of Exercise in Breast Cancer Survivors:Protocol
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DEVICE: Fit bit Device|BEHAVIORAL: Exercise Only|BEHAVIORAL: Connected Wellness HealthCoach Software|BEHAVIORAL: Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools
Status: UNKNOWN
Conditions: Developmental Disorders
Interventions: GENETIC: genome-wide analyses|GENETIC: Search for de novo mutations in paternal sperm samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer|Locally Advanced Cancer|Thoracic Cancer|Gynecologic Cancer|Genitourinary Cancer|Lymphoma
Interventions: BEHAVIORAL: Weekly 45 minute Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
Status: COMPLETED
Conditions: Erectile Dysfunction|Sexual Dysfunction, Physiological
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Test of "Dong-a Bepotastine Besilate Tab" and "Twolion Tab"
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fisrt period TWLO_C|DRUG: Fisrt period TWLO|OTHER: Washout period|DRUG: Second period TWLO_C|DRUG: Second period TWLO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Enavogliflozin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Lucentis (Ranibizumab 2.0mg) for the Treatment of Nonproliferative Idiopathic Parafoveal Telangiectasia
Status: COMPLETED
Conditions: Retinal Diseases|Telangiectasis
Interventions: DRUG: ranibizumab 2.0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-human Study of SAN711 in Healthy Participants
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: SAN711|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Time-restricted Eating and Endurance Training on Markers of the Health of Women and Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Exercise|Time Restricted Eating|Mental Health Wellness 1|Wellbeing|Biochemical Markers
Interventions: OTHER: Time restricted eating and exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cardiac Magnetic Resonance Imaging for Detecting Endothelial Dysfunction
Status: UNKNOWN
Conditions: Endothelial Dysfunction|Myocardial Perfusion Abnormalities|Cardiac MRI Perfusion With Vasomotor Stress|Diabetes
Interventions: PROCEDURE: Cardiac Perfusion MRI w Vasomotor Stress
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Sacubitril/Valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients With Ischemic Heart Failure With Mid-range Ejection Fraction
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Moderately Reduced Ejection Fraction
Interventions: DRUG: Sacubitril / Valsartan|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 1
Status: COMPLETED
Conditions: Solid Tumor|Pancreatic Neuroendocrine Tumor|Neuroendocrine Tumors
Interventions: DRUG: PAC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Neoplasms
Interventions: DRUG: Durvalumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients
Status: RECRUITING
Conditions: Kidney Transplant Recipients|Post-transplant Diabetes Mellitus|Type 2 Diabetes
Interventions: DRUG: Dapagliflozin 10 MG Oral Tablet|DRUG: Placebo Matching Dapagliflozin Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 691751 in Healthy Asian Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo to BI 691751|DRUG: BI 691751 high dose|DRUG: BI 691751 middle dose|DRUG: Placebo to BI 691751|DRUG: BI 691751 low dose 1|DRUG: Placebo to BI 691751|DRUG: Placebo to BI 691751|DRUG: BI 691751 low dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 5 Year Long-term Follow up in Pediatric Participants Who Received PegIntron Plus Rebetol in P02538 Part I (P02538 Pt 2)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tremelimumab and CP-870,893 in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: CD40 agonist monoclonal antibody CP-870,893|BIOLOGICAL: tremelimumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Repair Systems for Prolapse Repair
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: AMS Apogee™ with IntePro|DEVICE: AMS Apogee™ with Intexen LP|DEVICE: AMS Perigee™ with IntePro|DEVICE: AMS Perigee™ with IntePro Lite|DEVICE: AMS Apogee™ with IntePro Lite|DEVICE: AMS Elevate™ Apical & Posteiror with IntePro Lite|DEVICE: AMS Elevate™ Apical & Posteiror with IntXen LP|DEVICE: AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 1, For Study Use Only)|DEVICE: AMS Elevate™ Anterior & Apical with IntePro Lite (Gen 2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy in Treating Patients With Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Vehicle in Subjects With Blepharitis (P08636)
Status: TERMINATED
Conditions: Blepharitis
Interventions: DRUG: Azithromycin ophthalmic solution, 1%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Blinded Assessor, Trial Comparing Odor Levels Due to Different Hygiene Methods With PrePexTM
Status: COMPLETED
Conditions: Odor Levels of Study Arms
Interventions: PROCEDURE: Subjects cleaned the foreskin with soapy water using a syringe once a day.|PROCEDURE: Subjects cleaned the foreskin with diluted chlorhexidine (1%) using a syringe once a day.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Intervention for Social Biases in Eating Disorders
Status: COMPLETED
Conditions: Eating Disorders|Anorexia Nervosa|Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Self-Blame and Perspective-Taking Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cuevas Medek Exercises on Trunk Control and Balance in Children With Down Syndrome
Status: NOT_YET_RECRUITING
Conditions: Down Syndrome
Interventions: OTHER: cuevas medek technique (exercise)|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia
Status: UNKNOWN
Conditions: Total Knee Replacement Surgery
Interventions: DRUG: Spinal Block|DRUG: General anesthetic|DEVICE: Total knee replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of JTT-705 in Combination With Simvastatin 40 mg in Patients With Low High-Density Lipoprotein (HDL) Levels
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: JTT-705 600 mg and simvastatin 40 mg|DRUG: Placebo and simvastatin 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multidisciplinary "Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)" Intervention to Improve Maternal and Child Outcomes in Lesotho
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: OTHER: IMPROVE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcutaneous Mechanical Nerve Stimulation (TMNS) by Vibration in the Treatment of Incontinence
Status: WITHDRAWN
Conditions: Urinary Incontinence
Interventions: DEVICE: Transcutaneous mechanical nerve stimulation by A medical vibrator (FERTI CARE personel, Multicept A/S, Albertslund, Danmark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 1000 IU|DIETARY_SUPPLEMENT: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ASTX727 and Nivolumab in Squamous Cell Carcinoma of the Head and Neck
Status: WITHDRAWN
Conditions: Recurrent Squamous Cell Carcinoma of the Head and Neck|Metastatic Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: INQOVI (decitabine and cedazuridine)|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Methylphenidate ER in Patients With Schizophrenia to Improve Functional and Cognitive Outcomes
Status: RECRUITING
Conditions: Schizophrenia Schizoaffective
Interventions: DRUG: Apo-Methylphenidate ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonvisual Foot Examination for People With Diabetes and Visual Impairment
Status: COMPLETED
Conditions: Diabetes|Visual Impairment
Interventions: BEHAVIORAL: DSME with Nonvisual Foot Examination|BEHAVIORAL: DSME with Usual Foot Examination Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: Rapamycin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Safety and Efficacy Study of PCI of Gemcitabine and Chemotherapy in Patients With Cholangiocarcinomas
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: DRUG: Amphinex, Gemcitabine and Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the BB Box System on Postpartum Maternal Anxiety, Post Traumatic Stress and Mother-child Relationships
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Anxiety
Interventions: DEVICE: BB Box available|OTHER: No BB Box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of MP-424, Peginterferon Alfa 2b, and Ribavirin in Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MP-424(H), PEG-IFN-a-2b, RBV|DRUG: MP-424 (L), PEG-IFN-a-2b, RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Long Term of Benzodiazepine Use on Psychiatric Manifestation
Status: UNKNOWN
Conditions: Psychiatric Disorder|Benzodiazepine-Related Disorders
Interventions: BEHAVIORAL: Detailed interview with personal demographic data|BEHAVIORAL: Intelligence assessment using the Arabic version of the Wechsler Adult Intelligence Scale (WAIS)|BEHAVIORAL: The Arabic version of the Structured Interview for the Five-Factor Personality Model (SIFFM)|BEHAVIORAL: the Hamilton Depression Rating Scale|BEHAVIORAL: The Hamilton Anxiety Rating Scale|BEHAVIORAL: The Minnesota Multiphasic Personality Inventory-2 (MMPI-2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer
Status: COMPLETED
Conditions: Pharmacokinetics of Vepoloxamer|Healthy Volunteers|Renal Impaired
Interventions: DRUG: Vepoloxamer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Ketamine on Analgesia Post-Cardiac Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Normal Saline Flush, 0.9% Injectable Solution_#1|DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking- Randomised Controlled Pilot Trials
Status: COMPLETED
Conditions: Depression|Alcoholism
Interventions: OTHER: Supportive text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Plasmodium Falciparum LSA-3 Malaria Vaccine
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: arm I: PfLSA-3-rec with aluminium hydroxide as adjuvant|BIOLOGICAL: arm 2: PfLSA-3-rec with Montanide Isa 720 as adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prostate Vaporization Techniques in Canadian Hospital
Status: COMPLETED
Conditions: Direct Costs Excluding Capital Equipment Purchase|Operator (Surgeon) Completed Questionnaire|Operative Parameters (Time, Bleeding Etc)|Complications (Post-op Retention, Bleeding, Re-admission to Hospital, Infection Etc)|3 Month Efficacy Evaluation (Compared to Baseline) Using Validated Symptom Assessment Tools (See Outcome Metrics for Details)
Interventions: PROCEDURE: Clarion Evolve Laser Vaporization System|PROCEDURE: Olympus TURis Plasma Vaporization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures
Status: COMPLETED
Conditions: Implant Infection|Alveolar Bone Loss
Interventions: DEVICE: tissue level dental implant|DEVICE: Bone level dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MASCOT Registry of Patients With Myeloproliferative Neoplasms Associated Splanchnic Vein Thrombosis
Status: ENROLLING_BY_INVITATION
Conditions: Myeloproliferative Neoplasm|Splanchnic Vein Thrombosis|JAK2 V617
Interventions: COMBINATION_PRODUCT: Drugs, procedures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Moisturizer Mediated Prevention of Symptoms of Atopic Dermatitis in Early Childhood
Status: UNKNOWN
Conditions: Atopic Dermatitis|Infant, Newborn
Interventions: DRUG: SanaCutan Basiscreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Open-Label, Multiple Ascending Dose Study of RRx-001 and Nivolumab
Status: COMPLETED
Conditions: Malignant Solid Tumor|Lymphoma
Interventions: DRUG: RRx-001|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EMD 121974 in Treating Patients With Locally Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous/Nonmalignant Condition|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cilengitide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Infusion for Diabetes Related Vascular Complications
Status: UNKNOWN
Conditions: Peripheral Vascular Disease|Ischemia|Diabetic Foot
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells|BIOLOGICAL: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Footwear on the Clinical, Functional, and Biomechanical Aspects in Elderly Women With Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Flexible footwear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NAC Effect on Infertile Women With Endometrioma
Status: UNKNOWN
Conditions: Female Infertility|Endometrioma|Stress Oxidative
Interventions: DRUG: N-acetyl cysteine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment Of Bladder Tumors Stage And Grade By Outpatient Flexible Cystoscopy Performed By Urology Resident
Status: UNKNOWN
Conditions: Bladder Cancer|Flexible Cystoscopy|Non-muscle Invasive Bladder Cancer (NMIBC)|Pain, Postoperative
Interventions: DEVICE: Cystoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer
Status: RECRUITING
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Laparoscopic total gastrectomy|PROCEDURE: Open total gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Buprenorphine Into the SFGH AIDS Program
Status: COMPLETED
Conditions: HIV|Buprenorphine|Opioid Dependence
Interventions: OTHER: Integrated office-based buprenorphine treatment for opioid dependence in an HIV primary care setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: ECT-001 (UM171) expanded cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial
Status: COMPLETED
Conditions: Growth Hormone Deficiency, Pediatric|Endocrine System Diseases|Hormone Deficiency|Pituitary Diseases
Interventions: DRUG: TransCon hGH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma
Status: UNKNOWN
Conditions: Melasma
Interventions: OTHER: Iontophoresis|OTHER: Azelaic acid cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer With Low Risk Of Local Recurrence: Partial and Accelerated Radiation With Three-Dimensional Conformal Radiotherapy (3DCRT) Vs. Standard Radiotherapy After Conserving Surgery (Phase III Study
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: partial breast irradiation|RADIATION: whole breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: bupivacaine with hydromorphone|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Beclomethasone Dipropionate Improves Respiratory Lung Function in Preschool Children With Recurrent Wheezing
Status: COMPLETED
Conditions: Wheezing
Interventions: DRUG: Nebulized beclomethasone dipropionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esthetic and Radiographic Outcomes Following Immediate Implant Placement With Thin or Dehiscence Buccal Bone Wall
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw, Edentulous, Partially|Acquired Absence of Single Tooth
Interventions: PROCEDURE: buccal bone augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT