pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase 3 Study to Evaluate the Lot Consistency of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: CoVLP formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Transcranial Direct Current Stimulation (tDCS) to Study Implicit Motor Learning on Patients With Brain Injury
Status: WITHDRAWN
Conditions: Traumatic Brain Injury|Stroke
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Combined With Irinotecan as a Second-line Treatment for Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer|Angiogenesis|Chemotherapy Effect
Interventions: DRUG: Surufatinib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients
Status: RECRUITING
Conditions: Anxiety
Interventions: DEVICE: Pico G2 4K Headset with Applied VR software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Chemotherapy Neoadjuvant/Adjuvant of NSCLC
Status: RECRUITING
Conditions: Stage IIIB(N2) Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab 200 mg IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Proactive Outreach for Smokers With COPD
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive|Smoking
Interventions: BEHAVIORAL: Proactive Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: M. Hailey-Hailey: hSPCA1 Expression and Skin Structure Upon Laser Therapy
Status: COMPLETED
Conditions: Hailey Hailey Disease
Interventions: PROCEDURE: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiofrequency in Sacroiliac Arthropathy;Bipolar RF 6 Points Versus Monopolar RF at 6 and 3 Points
Status: COMPLETED
Conditions: Radiofrequency Ablation|Chronic Sacroiliac Joint Arthropathy
Interventions: PROCEDURE: radiofrequency ablation for sacroiliac joint arthropathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy To Limit Cognitive Dysfunction After Cardiac Surgery
Status: WITHDRAWN
Conditions: Neurocognitive Dysfunction
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Study of a Combination of MTA (LY231514) and Gemcitabine in Patients With Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: pemetrexed|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wildlife and Wellbeing: An Animal-Assisted Intervention for Veterans With PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: OTHER: Forest walk|OTHER: Wildlife rehabilitation|OTHER: Wildlife sanctuary observation|OTHER: Bird feeding and watching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Brivanib (BMS-582664) to Treat Multiple Tumor Types
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|Transitional Cell Carcinoma|Soft Tissue Sarcoma|Gastric/Esophageal Adenocarcinoma|Pancreatic Cancer Including Ampulla of Vater
Interventions: DRUG: brivanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Into Pain in Subacromial Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: exercising into pain|OTHER: exercising with no/slight pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parents Advancing Toddler Health
Status: RECRUITING
Conditions: Sleep Problem|Behavior, Child
Interventions: BEHAVIORAL: Sleep Health in Preschoolers (SHIP)|BEHAVIORAL: Family Check-Up (FCU)|BEHAVIORAL: Oral Health, Child Safety, and Environmental Health Intervention (Active Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|de Novo Myelodysplastic Syndrome|High Risk Myelodysplastic Syndrome|Inv(16)|Myelodysplastic Syndrome With Excess Blasts|t(16;16)|t(8;21)|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Decitabine|BIOLOGICAL: Filgrastim-sndz|DRUG: Fludarabine Phosphate|DRUG: Gemtuzumab Ozogamicin|DRUG: Idarubicin|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR)
Status: UNKNOWN
Conditions: Non-Proliferative Diabetic Retinopathy|Proliferative Diabetic Retinopathy New Vessels on Disc|Dry Eye Syndromes
Interventions: DRUG: Sodium Hyaluronate, Vitamin A, Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Clarithromycin, Lenalidomide and Dexamethasone in the Treatment of the First Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma in Relapse
Interventions: DRUG: Clarithromycin Lenalidomide Dexamethasone (BiRd) Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Placebo|DRUG: SHR117887
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Acute-graft-versus-host Disease
Interventions: BIOLOGICAL: Alpha-1 antitrypsin (AAT)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bortezomib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Duct Cell Adenocarcinoma of the Pancreas|Stage IV Pancreatic Cancer
Interventions: DRUG: bortezomib|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Optimal Calcium Supplement Following Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Roux-en-Y Gastric Bypass|Hyperparathyroidism, Secondary
Interventions: DIETARY_SUPPLEMENT: Calcium Carbonate|DIETARY_SUPPLEMENT: Calcium Citrate|DIETARY_SUPPLEMENT: Placebo|PROCEDURE: Roux-en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pretreatment With Intravenous Lidocaine for Intravenous Contrast:
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Preservative Free Lidocaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Resuscitation in Septic Shock Patients With BMI Elevation
Status: TERMINATED
Conditions: Sepsis|Septic Shock|Obesity
Interventions: PROCEDURE: Actual Body Weight Dosing|PROCEDURE: Adjusted Body Weight Dosing|PROCEDURE: Ideal Body Weight Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|Brain Metastases, Adult|Ras (KRAS or NRAS) Gene Mutation|BRAF Gene Mutation|HER2 Gene Mutation|MSI
Interventions: DIAGNOSTIC_TEST: Tumor samples will be tested for mutation status of KRAS, NRAS, BRAF, HER2 and MSI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Hygiene Reminders in Orthodontic Patients
Status: COMPLETED
Conditions: Compliance, Treatment
Interventions: BEHAVIORAL: WhatsApp reminder|BEHAVIORAL: Email reminder|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DEep VEin Lesion OPtimisation (DEVELOP) Trial
Status: UNKNOWN
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Endovenous ablation + iliac US +/- iliac stenting|DEVICE: Endovenous ablation of Great Saphenous Vein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of an Environmental Counsellor's Home Stay in Children Treated for Asthma or Allergic Rhinitis Via a Standardized Medical Questionnaire Randomized Controlled Superiority Trial in Parallel Arms, Multicentric (EvalPCE)
Status: RECRUITING
Conditions: Category 3 Study (Non-interventional Research)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Long-Term Effect of Frequent Anti-VEGF Dosing on Retinal Function in Patients With Neovascular AMD
Status: UNKNOWN
Conditions: Electrophysiology
Interventions: PROCEDURE: Electroretinography (ERG), Visual Evoked Potentials (VEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Artificial Inteligent for Diagnosing Drug-Resistant Tuberculosis
Status: COMPLETED
Conditions: MDR Tuberculosis|Resistance to Tuberculostatic Drugs
Interventions: DIAGNOSTIC_TEST: Rapid Molecular Drug-Resistant Tuberculosis Test|OTHER: Artificial Intelligent Model|DIAGNOSTIC_TEST: Drug Susceptibility Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Program or Health Education Program in Reducing Fatigue and Pain in Breast Cancer Survivors
Status: UNKNOWN
Conditions: Breast Cancer|Cancer Survivor|Fatigue|Pain
Interventions: BEHAVIORAL: exercise intervention|OTHER: educational intervention|PROCEDURE: complementary or alternative medicine procedure|PROCEDURE: fatigue assessment and management|PROCEDURE: management of therapy complications|PROCEDURE: pain therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Prostate Artery Embolization (PAE) for Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DEVICE: Prostate Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia
Status: TERMINATED
Conditions: COVID|Corona Virus Infection|Viral Pneumonia
Interventions: BIOLOGICAL: Convalescent anti-SARS-CoV-2 plasma|OTHER: Infusion placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: cyclophosphamide|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Schizophrenia
Interventions: PROCEDURE: rTMS, "repetitive transcranial magnetic stimulation"|OTHER: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
Status: RECRUITING
Conditions: Neuroblastoma|Pheochromocytoma
Interventions: RADIATION: iobenguane I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Building Emotional Awareness and Mental Health in Parenting (BEAM)
Status: RECRUITING
Conditions: Parent Mental Health|Parenting|Child Mental Health|Child Development
Interventions: BEHAVIORAL: Building Emotion Awareness and Mental Health (BEAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use Babyguard® Breast Milk Probiotics to Verify the Authenticity of the Gut-Breast Axis Hypothesis
Status: RECRUITING
Conditions: Intestinal Bacteria Flora Disturbance
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Babyguard® Breast Milk Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-951 to Stop Adults Getting Nausea and Vomiting After Planned Surgery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting (PONV)
Interventions: DRUG: TAK-951|DRUG: Ondansetron|DRUG: Ondansetron Placebo|DRUG: TAK-951 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Routine Staple Line Reinforcement for Minimally Invasive Distal Pancreatectomy
Status: UNKNOWN
Conditions: Pancreas Neoplasm|Stump|Surgery--Complications
Interventions: PROCEDURE: reinforcement of the staple line|PROCEDURE: staple only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Perioperative Transfusion on Postoperative Cognitive Dysfunction
Status: RECRUITING
Conditions: POCD|Anemia|Transfusion
Interventions: PROCEDURE: blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy, Tislelizumab With Afatinib for HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Nab-paclitaxel|DRUG: Cisplatin|BIOLOGICAL: Tislelizumab|DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness of Spyglass Direct Visualization System Facilitated Management for the Patients With Intrahepatic Bile Duct Stone and/or Large Extrahepatic Bile Duct Stone
Status: UNKNOWN
Conditions: Patients With Large or Impacted Intra- or Extra-hepatic Bile Duct Stone
Interventions: DEVICE: ERCP using SpyGlass™ DS Direct Visualization System|OTHER: PTCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Modified Obturator Nerve Block Technique
Status: COMPLETED
Conditions: Hip Surgery|Knee Surgery
Interventions: PROCEDURE: obturator nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1558 in Healthy Adult Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: DWJ1558|DRUG: DWC202310 and DWC202311
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Disclosing Plaque Agent as a Guide to Remove the Oral Biofilm in Orthodontic Patients.
Status: COMPLETED
Conditions: Plaque
Interventions: DIAGNOSTIC_TEST: Plaque Disclosing Agent|DEVICE: Airpolishing and ultrasonic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate Safety and Tolerability of Peginesatide for Long-Term Treatment of Anemia in Participants With CKD
Status: TERMINATED
Conditions: Chronic Renal Failure|Chronic Kidney Disease|Anemia
Interventions: DRUG: peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Thioridazine in Combination With Cytarabine to Treat Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Thioridazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Tripegfilgrastim in Pediatric Solid Tumor/Lymphoma Patients
Status: COMPLETED
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: Tripegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety, Tolerability and Pharmacokinetics After Single and Multiple Doses of AZD1446 to Japanese Subject
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1446|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesia in Labor, a Prospective Parallel Study to Compare Regional Analgesia and Intravenous (IV) Pethidine Analgesia
Status: COMPLETED
Conditions: Labor Active Dilated Cm
Interventions: OTHER: Epidura, CSE & IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Pneumatic Compression in Women With Lipo-lymphedema (Lipedema With Swelling)
Status: COMPLETED
Conditions: Lipedema|Lipolymphedema
Interventions: DEVICE: Flexitouch Plus and Conservative Care|OTHER: Conservative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Latarjet vs Anatomic Glenoid Reconstruction
Status: RECRUITING
Conditions: Shoulder Dislocation|Bone Loss|Arthroscopy
Interventions: PROCEDURE: Coracoid Transfer|PROCEDURE: Distal Tibia Allograft with Bankart repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autonomous Nervous System Regulated Paediatric Anaesthesia With Dexmedetomidine or Placebo
Status: NOT_YET_RECRUITING
Conditions: Postoperative Confusion|Postoperative Delirium|Postoperative Pain, Acute|Postoperative Complications
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer|Gastric Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: docetaxel|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Thymoma|Thymic Carcinoma|Clinical Masaoka Stage II to IVA
Interventions: DRUG: Cetuximab, Cisplatin, Doxorubicin & Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Balance and Respiratory Muscle Training on Functional Capacity, Balance, Respiratory Function and Respiratory Muscle Strength in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Conventional physiotherapy including balance exercises|OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Osteoarthritis With Autologous, Microfragmented Adipose Tissue.
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: autologous, micro-fragmented adipose tissue|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis
Status: UNKNOWN
Conditions: Dermatopolymyositis|Interstitial Lung Disease
Interventions: DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMbination Regimens in MM Post AHCT to elimiNate MRD Utilizing IbERdomide
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Daratumumab|DRUG: Dexamethasone|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing The Efficacy And Safety Of 2 Different Initial Dose Prescriptions For Exubera.
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Inhaled Human Insulin (Exubera)|DRUG: Inhaled Human Insulin (Exubera)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Entire Papilla Preservation Technique For Treatment Of Intrabony Defects. Clinical Trial.
Status: UNKNOWN
Conditions: Periodontitis|Regeneration
Interventions: PROCEDURE: Modified Entire Papilla Preservation Technique (MEPPT) For Periodontal Regenerative Treatment Of Intrabony Defects.|DEVICE: Emdogain (EMD), Biomaterials (allograft, subepithelial connective tissue graft/sCTG)|PROCEDURE: Modified Entire Papilla Preservation Technique (MEPPT) with Emdogain For Periodontal Regenerative Treatment Of Intrabony Defect|PROCEDURE: Modified Entire Papilla Preservation Technique (MEPPT) with Emdogain and Allograft For Periodontal Regenerative Treatment Of Intrabony Defect|PROCEDURE: Modified Entire Papilla Preservation Technique (MEPPT) with Emdogain and Allograft and sCTG For Periodontal Regenerative Treatment Of Intrabony Defect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients
Status: COMPLETED
Conditions: Stem Cell Transplant Complications
Interventions: DRUG: Chlorhexidine Gluconate 2% Wipe|DRUG: Placebo Wipe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: WHISH-2-Prevent Heart Failure
Status: UNKNOWN
Conditions: Physical Activity|Heart Failure|Heart Failure With Reduced Ejection Fraction|Heart Failure With Normal Ejection Fraction|Strength Training|Elderly|Women
Interventions: BEHAVIORAL: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients
Status: UNKNOWN
Conditions: Cytochrome P-450 CYP2B6|Efavirenz|HIV
Interventions: DRUG: Efavirenz|DRUG: Efavirenz|OTHER: CYP450 2B6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myo-inositol Plus Melatonin in Perimenopausal Women
Status: UNKNOWN
Conditions: Perimenopause
Interventions: DIETARY_SUPPLEMENT: Myo-Mel|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor vs Clopidogrel Effect on MFR in CAD Population
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Herbal Patch for Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: herbal patch|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)
Status: COMPLETED
Conditions: Chronic Lymphoproliferative Diseases
Interventions: DRUG: GRN163L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Rohto Dry-Aid® and Systane® Ultra in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes|Dry Eye
Interventions: DRUG: Rohto Dry-Aid®|DRUG: Systane® Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tidal Volume Change on Pressure-based Prediction of Fluid Responsiveness in Children
Status: COMPLETED
Conditions: Plasma Volume|Tidal Volume
Interventions: PROCEDURE: Tidal volume_6mL/kg|PROCEDURE: Tidal volume_10mL/kg|PROCEDURE: Tidal volume_14mL/kg|PROCEDURE: Fluid loading
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Treatment for Teens With Alcohol Abuse and Depression
Status: COMPLETED
Conditions: AOD Use, Abuse, and Dependence|Depression
Interventions: BEHAVIORAL: MET/CBT-12|BEHAVIORAL: CBT-D|OTHER: D-TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment of gBRCA-Mutated HER2-Negative Breast Cancer With HRS-1167 and Famitinib ± Camrelizumab
Status: NOT_YET_RECRUITING
Conditions: BRCA-Mutated Breast Carcinoma|HER2-negative Breast Cancer
Interventions: DRUG: HRS-1167|DRUG: Famitinib|DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CAT-8015 Immunooxin in Patients With HCL With Advance Disease
Status: UNKNOWN
Conditions: Leukemia|Hairy Cell Leukemia|HCL
Interventions: DRUG: Immunotoxin therapy|DRUG: CAT-8015 Immunotoxin|PROCEDURE: Biological therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Paclitaxel-induced Neuropathic Pain in Patients With Planned Paclitaxel Chemotherapy (PrevTel)
Status: COMPLETED
Conditions: Neuropathic Pain|Chemotherapy Effect
Interventions: DRUG: Telmisartan tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Electro-acupuncture and Flumazenil's Effect on Sedation
Status: COMPLETED
Conditions: Acupuncture|General Anaesthesia|Sedation
Interventions: DRUG: Flumazenil|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 4 Post-marketing Study of Intramuscular Injections of BLB-750 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Pandemic Influenza Prevention
Interventions: BIOLOGICAL: BLB-750 Vaccine (Qinghai RG strain)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Methotrexate|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Status: NOT_YET_RECRUITING
Conditions: Cough|Vocal Cord Atrophy|Vocal Cord Paresis|Vocal Cord Paralysis|Dysphagia|Dysphonia
Interventions: DIAGNOSTIC_TEST: Ultrasound for cough|DIAGNOSTIC_TEST: Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis|DIAGNOSTIC_TEST: Ultrasound for dysphagia|DIAGNOSTIC_TEST: Ultrasound for dysphonia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 3D Ultrasound - Based Hysteroscopy Versus Virtual Hysteroscopy
Status: TERMINATED
Conditions: Endometrial or Uterine Pathology
Interventions: DEVICE: Medison Accuvix V20, sonde 3D5-9EK (Endovaginal 3 dimensional echography)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Outpatient Psychotherapeutic Treatment for Alcohol Dependent Individuals With Comorbid Psychiatric Disorders
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: BEHAVIORAL: Outpatient Cognitive Behavioral Psychotherapy|BEHAVIORAL: Outpatient Cognitive Behavioral Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Safety and Performance of a Medical Device (ClearPlasma) for the Treatment of Patients With Acute Upper Gastrointestinal Hemorrhage.
Status: COMPLETED
Conditions: Acute Upper Gastrointestinal Hemorrhage|Acute Upper Gastrointestinal Bleeding
Interventions: OTHER: Plasma treated with ClearPlasma (Extra-corporeal plasma filtration device)|OTHER: Regular fresh-frozen plasma (not treated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Interval Training on Fatigue Level and Functional Performance in Post Angioplasty Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Aerobic Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine Immediate Release (IR)|DRUG: Nevirapine Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: hCT-MSCs for COVID19 ARDS
Status: TERMINATED
Conditions: COVID|Corona Virus Infection|COVID19
Interventions: BIOLOGICAL: Human cord tissue mesenchymal stromal cells (hCT-MSC) manufactured by Duke University.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Ramelteon in Elderly Subjects
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Ramelteon, zolpidem and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of the Probiotic Strains Limosilactocillus Reuteri DSM 32910 and Lacticaseibacillus Paracasei DSM 32851 on Glucose Homeostatis in Prediabetic Adults
Status: COMPLETED
Conditions: Prediabetic State|Dysglycemia
Interventions: DIETARY_SUPPLEMENT: NZ-GHMH-01|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Amiloride Clinical Trial In Optic Neuritis
Status: COMPLETED
Conditions: Optic Neuritis|Multiple Sclerosis
Interventions: DRUG: Amiloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults
Status: RECRUITING
Conditions: Chronic Venous Leg Ulcers
Interventions: DIETARY_SUPPLEMENT: EPA+DHA|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
Status: RECRUITING
Conditions: Acute Pancreatitis
Interventions: DRUG: RABI-767
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation and Ventilator Weaning Protocol in PICU
Status: UNKNOWN
Conditions: Mechanical Ventilation|Sedation
Interventions: OTHER: Sedation and ventilator weaning protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Dapagliflozin Provide Additional Health Benefits To Dietary Counseling For Weight Loss?
Status: COMPLETED
Conditions: Weight Loss
Interventions: DRUG: Dapagliflozin Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serious Games Rehabilitation Programme to Treat Gait and Balance Disorders in PD Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Serious game|DEVICE: Placebo serious game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Metastatic Gastric Adenocarcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Camrelizumab|DRUG: Apatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083
Status: COMPLETED
Conditions: Growth Hormone Disorder|Adult Growth Hormone Deficiency
Interventions: DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Multiple Intravenous Doses of MEDI 545 in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus
Interventions: BIOLOGICAL: MEDI 545|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
Status: COMPLETED
Conditions: Postpartum Depression|Major Depressive Disorder|Postpartum Psychosis|Menopause|Neurodegeneration|Schizophrenia
Interventions: DRUG: Goserelin 3.6 mg implant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Citrate- Versus Acetate-Based Dialysate in Bicarbonate Haemodialysis: Consequences on Haemodynamics, Coagulation, Acid-Base Status and Electrolytes
Status: COMPLETED
Conditions: Haemodialysis
Interventions: OTHER: Citrate dialysate|OTHER: Acetate dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Contents of Circulating Extracellular Vesicles: Biomarkers in Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: analysis (protein, lipid, RNA ...) of circulating exosomes, size and number|OTHER: Gathering additional information about the patient's cancer|DIAGNOSTIC_TEST: Diagnostic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Luspatercept in Lower-risk Myelodysplastic Syndrome Participants
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Effects of Levonorgestrel and Ethinyl Estradiol on Ovulation
Status: COMPLETED
Conditions: Ovulation
Interventions: DRUG: Levonorgestrel|DRUG: Ethinyl Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab
Status: RECRUITING
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Isatuximab intravenous (IV)|DRUG: Cemiplimab (SAR439684)|DRUG: Dexamethasone|DRUG: Lenalidomide|DRUG: Pomalidomide|DRUG: Isatuximab subcutaneous (SC)|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Mechanism of Action of Dietary Fibre on the Gut Microbiota and Metabolites
Status: RECRUITING
Conditions: Psyllium|Inulin
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Psyllium|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate
Status: NOT_YET_RECRUITING
Conditions: Symptom, Cognitive|Schizophrenia|Schizo Affective Disorder
Interventions: DRUG: Sodium Benzoate 2gram/day|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IIC-IV Melanoma
Status: COMPLETED
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size|Ciliary Body and Choroid Melanoma, Small Size|Extraocular Extension Melanoma|Iris Melanoma|Metastatic Intraocular Melanoma|Mucosal Melanoma|Recurrent Intraocular Melanoma|Recurrent Melanoma|Stage IIC Melanoma|Stage IIIA Intraocular Melanoma|Stage IIIA Melanoma|Stage IIIB Intraocular Melanoma|Stage IIIB Melanoma|Stage IIIC Intraocular Melanoma|Stage IIIC Melanoma|Stage IV Intraocular Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: gp100 antigen|BIOLOGICAL: tyrosinase peptide|BIOLOGICAL: recombinant MAGE-3.1 antigen|BIOLOGICAL: multi-epitope melanoma peptide vaccine|BIOLOGICAL: incomplete Freund's adjuvant|DRUG: Montanide ISA 51 VG|DRUG: agatolimod sodium|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Interventional Pulmonologic Treatment of Benign Central Airway Fibrotic Stricture
Status: UNKNOWN
Conditions: Obstructive Airway Disease
Interventions: DEVICE: balloon dilation|PROCEDURE: cryotherapy|PROCEDURE: spiculiform electrosurgery|DRUG: mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900010 in Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: LY2452473|DRUG: tadalafil|DRUG: placebo (tadalafil)|DRUG: placebo (LY2452473)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block
Status: UNKNOWN
Conditions: Injuries, Hand|Anesthesia Conduction|Anesthetics, Local
Interventions: DRUG: Bupivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: 9vHPV Vaccine|OTHER: Placebo (Saline for Injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Visualization of Carotid Atherosclerosis by 68Ga-MSA
Status: COMPLETED
Conditions: Atherosclerosis|Carotid Atherosclerosis|Noninvasive Imaging of Atherosclerosis
Interventions: OTHER: 68Gallium-MSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IUD and Norethindrone Acetate for Treatment of Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: DRUG: norethindrone acetate (NETA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-Based Pulmonary Rehab for Patients With Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BEHAVIORAL: Physical exercise training|BEHAVIORAL: Cognitive exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT