pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Plant Stanol Esters and COVID-19 Vaccination Response
Status: TERMINATED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Plant stanol mini drinks|DIETARY_SUPPLEMENT: Placebo mini drinks|BIOLOGICAL: COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Restrictive Versus Liberal Perioperative Fluid Management for Patients Undergoing Pancreatic Resection
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: OTHER: restrictive perioperative fluid management|OTHER: Liberal perioperative fluid management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy With Mesenchymal Stem Cell in Ischemic Limb Disease
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: DRUG: Allogenic MSC|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bathing and Moisturizers on Skin Hydration in Atopic Dermatitis: an in Vivo Study
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: PROCEDURE: bathing and moisturizer application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refractory T or B Cell Malignancies (COBALT-LYM)
Status: ACTIVE_NOT_RECRUITING
Conditions: T Cell Lymphoma
Interventions: BIOLOGICAL: CTX130
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Sublingual and Buccal Misoprostol Regimens After Mifepristone for Mid-trimester Abortion
Status: UNKNOWN
Conditions: Legally Induced Abortion Without Mention of Complication
Interventions: DRUG: Mifepristone|DRUG: Buccal misoprostol|DRUG: Sublingual misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DEVICE: Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit|DEVICE: Transcranial direct current stimulation (tDCS) Soterix Medical Inc. tDCS unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post-traumatic Seizures With Levetiracetam
Status: TERMINATED
Conditions: Epilepsy, Post-Traumatic
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open-Labeled PK-PD Studies of Metoprolol ER
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DRUG: brand name metoprolol ER|DRUG: Generic A|DRUG: Generic B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Percutaneous Coronary Intervention
Interventions: DRUG: Ticagrelor, Prasugrel, Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Web-Based Education on Symptoms and Quality of Life in University Students With Premenstrual Syndrome
Status: COMPLETED
Conditions: Premenstrual Syndrome|Quality of Life
Interventions: BEHAVIORAL: A web-based education intervention developed for university students with PMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Efficacy and Safety of TQC3564 Tablets in the Treatment of Persistent Allergic Rhinitis
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: TQC3564 tablets|DRUG: Placebo tablets|DRUG: TQC3564 tablets, montelukast sodium tablets|DRUG: Placebo tablets, montelukast sodium tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: AZD1386|DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Beta 2-mimetics in the Treatment of Neuropathic Pain
Status: TERMINATED
Conditions: Postthoracotomy Pain|Postthoracoscopy Neuropathic Pain
Interventions: DRUG: Terbutaline sustained release 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REPEAT Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Therapy in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Who Did Not Respond to Previous PegIntron (Peginterferon Alfa-2b (12KD))/Ribavirin Combination Therapy
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Ribavirin|DRUG: Ribavirin|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ideal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Abortion
Status: NOT_YET_RECRUITING
Conditions: Incomplete Abortion|Intrauterine Contraception|Misoprostol
Interventions: DEVICE: Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga PSMA in Preprostatectomy Patients
Status: COMPLETED
Conditions: Prostate Cancer|Prostatic Neoplasm|Prostatic Neoplasms, Castration-Resistant|Prostatic Neoplasm of Uncertain Behavior
Interventions: DRUG: Ga-68 PSMA-HBED-CC PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Blood Donations in Adults Vaccinated With rMenB+OMV NZ.
Status: COMPLETED
Conditions: Meningitis, Meningococcal, Serogroup B
Interventions: BIOLOGICAL: Meningococcal (group B) multicomponent recombinant adsorbed vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment Of Partial Reversible Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol 250/50 DISKUS combination product|DRUG: fluticasone propionate DISKUS 500mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating MicroRNAs in Understanding Pathogenesis of Systemic Lupus Erythematosis
Status: COMPLETED
Conditions: Systemic Lupus Erythematosis
Interventions: DRUG: Cyclophosphamide|DRUG: Hydroxychloroquine|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Fecal Microbiota Transplantation in Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Fecal Microbiota Transplantation (FMT)|DRUG: Sham-transplantation Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Cognitive-Behaviour Therapy for Irritable Bowel Syndrome and the Gut Microbiome
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Group Cognitive Behaviour Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigative Headgear With Nasal Pillows Continuous Positive Airway Pressure (CPAP) Mask
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Investigative Headgear with CPAP mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity
Status: COMPLETED
Conditions: Muscle Spasticity|Cerebrovascular Accident
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Myeloablative HLA-Mismatched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies
Status: TERMINATED
Conditions: Lymphoma|Leukemia|Multiple Myeloma|Myelodysplastic Syndrome
Interventions: DRUG: MEDI-507|PROCEDURE: Non-myeloablative Ex-Vivo T-cell Depleted PBSC Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Aortic Valve Implantation Without Predilation
Status: COMPLETED
Conditions: Aortic Stenosis|Left Ventricular Function Systolic Dysfunction|High-risk Patients|Transcatheter Aortic Valve Implantation
Interventions: PROCEDURE: TAVI without BAV|PROCEDURE: TAVI standard procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Hypertension SOLAR
Status: RECRUITING
Conditions: Interstitial Lung Disease|COPD|Pulmonary Arterial Hypertension
Interventions: DRUG: Hyperpolarized 129Xe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Sleep|Fatigue|Anxiety|Cancer|Depression
Interventions: DRUG: Melatonin|OTHER: Placebo for Melatonin|DRUG: Melatonin|DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease
Status: COMPLETED
Conditions: Chronic Pelvic Pain
Interventions: DRUG: Jincaopian Tablets high dose|DRUG: Jincaopian Tablets low dose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Breast MRI and Biomarker Strategies in Identifying High-risk Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subject
Interventions: PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Increasing Engagement in PTSD Treatment Through Patient Education and Patient Choice
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Informed decision making|BEHAVIORAL: Placebo session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TEOSYAL® PureSense Redensity [I] Injection Using MicronJet® Needle in the Treatment of Crow's Feet Wrinkles
Status: COMPLETED
Conditions: Crow's Feet Wrinkles
Interventions: DEVICE: TEOSYAL® PureSense Redensity [I]/MicronJet®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin for Treatment of Seborrhic Dermatitis in Parkinsonian Patients
Status: UNKNOWN
Conditions: Parkinson Disease|Parkinsonism|Seborrheic Dermatitis
Interventions: DRUG: Botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis
Status: TERMINATED
Conditions: Essential Thrombocythemia|Polycythemia Vera|Primary Myelofibrosis
Interventions: DRUG: Arsenic Trioxide|DIETARY_SUPPLEMENT: Ascorbic Acid|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan + HCTZ|DRUG: Valsartan|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Dexamethasone as an Adjunct to a Brachial Plexus Block in Patients Undergoing Orthopaedic Surgery of the Forearm and Hand
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Dexamethasone 12 mg|DRUG: Placebo|DRUG: Dexamethasone 24 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Investigational Study: Treatment of Anxiety With Non-Needle Electro-Acupuncture
Status: COMPLETED
Conditions: Anxiety, Mild to Moderate
Interventions: DEVICE: HANS non-needle acupuncture|PROCEDURE: Stimulation of two acupuncture points bi-lateral
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
Status: RECRUITING
Conditions: Colon Cancer|dMMR Colorectal Cancer
Interventions: DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER.
Status: UNKNOWN
Conditions: The Primary Study Objective is to Assess the Efficacy and|Safety of Extended 4-week Heparin Prophylaxis Compared to|Prophylaxis Given for 8±2 Days After Planned Laparoscopic|Surgery for Colorectal Cancer.|The Clinical Benefit Will be Evaluated as the Difference in|the Incidence of VTE or VTE-related Death Occurring Within 30 Days|From Surgery in the Two Study Groups.
Interventions: DRUG: Heparin, Low-Molecular-Weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbiota Transplantation for Early Clostridioides Difficile Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Clostridium Difficile Infection|Clostridioides Difficile Infection
Interventions: OTHER: Fecal microbiota transplantion (FMT)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Rigosertib for Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Anal Squamous Cell Carcinoma|Lung Squamous Cell Carcinoma|Cervical Squamous Cell Carcinoma|Esophageal Squamous Cell Carcinoma|Skin Squamous Cell Carcinoma|Penile Squamous Cell Carcinoma
Interventions: DRUG: rigosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing GI: Exploring an Optimum Glycaemic Profile for Cognitive Function Across the Day
Status: COMPLETED
Conditions: Cognitive Performance|Glucose, Low Blood|Glucose, High Blood|Mood
Interventions: DIETARY_SUPPLEMENT: Low Glycaemic Diet|DIETARY_SUPPLEMENT: High Glycaemic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Chronic Disease|Secondary Prevention|Coronary Disease
Interventions: BEHAVIORAL: (Health education program) To increase therapeutic adherence in patients with secondary prevention for cardiovascular disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PET Imaging of Extrathalamic α4β2-nicotinic Acetylcholine Receptors in Health and Disease With [18F]XTRA
Status: TERMINATED
Conditions: Measure of Uptake of XTRA in the Brain
Interventions: RADIATION: Positron Emission Tomography (PET) Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Convalescent Plasma Therapy in Severely Sick COVID-19 Patients
Status: COMPLETED
Conditions: COVID
Interventions: DRUG: Convalescent Plasma Transfusion|OTHER: Supportive Care|DRUG: Random Donor Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery
Status: TERMINATED
Conditions: Stomach Neoplasms|Esophageal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Impact|DIETARY_SUPPLEMENT: Glucose load
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss and Abdominal Fat Responses to Different Diet Compositions
Status: UNKNOWN
Conditions: Obesity|Insulin Resistance|Metabolic Syndrome
Interventions: OTHER: Low Carbohydrate Diet|OTHER: Low Fat Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of AGE on the Immune System
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Aged Garlic Extract Supplementation Group|OTHER: Standard for Groups|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Integrated Telerehabilitation of COPD Patients. A Multi-Center Trial
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Exercise training at home|BEHAVIORAL: Telemonitoring and education/self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Open-Label Dose Finding Study of SGN-35 for CD30 Positive Hematologic Malignancies
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Disease, Hodgkin|Lymphoma, Large-Cell, Anaplastic
Interventions: DRUG: SGN-35
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: liraglutide|DRUG: insulin detemir|DRUG: liraglutide plus insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Ketamine on Postoperative Cognitive Dysfunction.
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pivotal Study (Pharmacokinetics, Efficacy, Safety) of BAX 326 (rFIX) in Hemophilia B Patients
Status: COMPLETED
Conditions: Hemophilia B
Interventions: BIOLOGICAL: BAX 326|BIOLOGICAL: BeneFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Anterior Lamellar Keratoplasty (DALK) Using Acellular Corneal Tissue Promotes Corneal Allograft Survival in High Risk Patients
Status: COMPLETED
Conditions: Glycerin Cryopreserved Acellular Corneal Tissue|Deep Anterior Lamellar Keratoplasty|High Risk Keratoplasty
Interventions: PROCEDURE: DALK using GCCT|PROCEDURE: DALK using FCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma
Status: WITHDRAWN
Conditions: BRAF V600 Mutation|Unresectable Melanoma|Metastatic Melanoma|Hepatic Impairment
Interventions: DRUG: Encorafenib + Binimetinib|DRUG: Encorafenib + Binimetinib|DRUG: Encorafenib + Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avatrombopag vs. Placebo for CIT in GI Malignancies
Status: RECRUITING
Conditions: Gastrointestinal Cancer|Gastrointestinal Neoplasms|Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: Avatrombopag|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Release of Organic Components of a GIOMER in Non-carious Cervical Lesion Restorations
Status: COMPLETED
Conditions: Non-carious Cervical Lesions
Interventions: OTHER: Device: SHOFU beautifil II LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Intrathecal Analgesia in Appendectomy
Status: COMPLETED
Conditions: Anesthesia|Analgesia
Interventions: DRUG: 25 mcg fentanyl|DRUG: 250 mcg alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Oxytocin on Emotion Recognition and Response Inhibition
Status: UNKNOWN
Conditions: The Impact of Oxytocin on Social Cognition
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits
Status: COMPLETED
Conditions: Conduct Disorder|Oppositional Defiant Disorder
Interventions: BEHAVIORAL: Reward-Emphasized Treatment|BEHAVIORAL: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of the Gut-brain Axis by Cranberries: Impact on University Students' Mental Wellbeing
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Cranberry juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cetuximab, Capecitabine, Oxaliplatin and Bevacizumab in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 21Capecitabine + bevacizumab + oxaliplatin|DRUG: 1Capecitabine + oxaliplatin + bevacizumab + cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC
Status: COMPLETED
Conditions: Refractory Metastatic Colorectal Cancer
Interventions: DRUG: TAS-102|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia
Status: COMPLETED
Conditions: Bradycardia
Interventions: DRUG: CARDIX-101A, CARDIX-101B, CARDIX-101C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insomnia in Older Adults: Impact of Personalized, Diet-Induced Alterations in the Microbiota
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: PDM nutritional intervention|BEHAVIORAL: General information on nutrition and health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Digestive Functions and the Enteric Nervous System in Obesity. Investigations of Relationships With Metabolism Disorders (EnteroNeurObesity)
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Digestive functions investigations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Tomotherapy on Xerostomia and Quality of Life of Patients With Cancer of the Upper Aero-digestive Tract
Status: TERMINATED
Conditions: Head and Neck Cancer|Radiotherapy by Tomotherapy Exclusive|With or Without Concurrent Chemotherapy
Interventions: RADIATION: Tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Status: COMPLETED
Conditions: Asthma|Exercise-Induced Bronchoconstriction
Interventions: DIETARY_SUPPLEMENT: Lyprinol|DIETARY_SUPPLEMENT: Placebo (Olive Oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain in Carpal Tunnel Release Wide-awake Local Anesthesia With no Tourniquet vs Local Anesthesia With Tourniquet
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Carpal tunnel release, WALANT technique|PROCEDURE: Carpal tunnel release using a tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort Study
Status: TERMINATED
Conditions: Raynaud Disease|Systemic Sclerosis|Digital Ulcer
Interventions: DRUG: Calcium Channel Blockers|DRUG: Phosphodiesterase Inhibitors|DRUG: Endothelin receptor blocker|DRUG: Prostanoids|DRUG: Other vasodilator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
Status: RECRUITING
Conditions: Asthma|Pulmonary Function|Wheezing|In Utero Nicotine
Interventions: DIETARY_SUPPLEMENT: No active intervention in this protocol (previously randomized to Vitamin C)|OTHER: No active intervention in this protocol (previously randomized to Placebo)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Aphasia
Interventions: BEHAVIORAL: Persons with Aphasia Training Dogs Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation in Patients With Lung Impairment Controlled by the Mechanical Energy of the Respiratory System
Status: RECRUITING
Conditions: ARDS|Lung Injury, Ventilator Induced
Interventions: PROCEDURE: Mechanical energy monitoring|PROCEDURE: Conventional mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of IVR and WEB Alcohol Interventions
Status: COMPLETED
Conditions: Alcohol Consumption
Interventions: BEHAVIORAL: Single WEB intervention|BEHAVIORAL: Repeated WEB intervention|BEHAVIORAL: Single IVR intervention|BEHAVIORAL: Repeated IVR intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Targeted Protein Fortification in Extremely Low Birth Weight Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Infants
Interventions: DIETARY_SUPPLEMENT: Standard Protein Diet|DIETARY_SUPPLEMENT: High Protein Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Direct Current Stimulation in Acute Ischemic Stroke Treatment
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Soterix Medical 1X1 tDCS stimulator (active C-tDCS)|DEVICE: Soterix Medical 1X1 tDCS stimulator (sham stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass
Status: ENROLLING_BY_INVITATION
Conditions: Congenital Heart Disease|Congenital Heart Defect|Congenital Heart Malformations
Interventions: DRUG: Nitric Oxide (NO) 20 part per million (ppm)|OTHER: Standard of care cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Oral Ziprasidone Versus Conventional Dosing in Participants With Residual Schizophrenia Symptoms
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Ziprasidone 80-160 mg/d|DRUG: Placebo|DRUG: Ziprasidone 160 mg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Fibroid Embolization (UFE) for Symptomatic Fibroids: Comparison of Gel-Bead to Commonly Used Embolic Agents.
Status: COMPLETED
Conditions: Uterine Fibroid|Embolization|Symptoms
Interventions: DEVICE: Gel-Beads embolic material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NovoTTF-100L in Combination With Pemetrexed (Alimta®) for Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|NSCLC
Interventions: DEVICE: NovoTTF-100L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Skill Fibreoptic Glottis View in Obese Patients: Ramp vs Supine Sniffing Air Position
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Ramped position|PROCEDURE: Supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 68Ga-NY104 PET/CT in Von Hippel-Lindau Disease
Status: RECRUITING
Conditions: Von Hippel-Lindau Disease
Interventions: DIAGNOSTIC_TEST: 68Ga-NY104 PET/CT Contrast-enhanced MRI of the brain and contrast-enhanced CT of abdomen and pelvis) 68Ga-NODAGA-LM3 PET/CT (exploratory)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Evaluate the Safety and Efficacy of the Saline-coupled Bipolar Sealer in Primary Unilateral Total Knee Arthroplasty
Status: COMPLETED
Conditions: Surgical Blood Loss
Interventions: DEVICE: Saline-coupled Bipolar Sealer|DEVICE: Unipolar electrocautery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus (RAD001)|DRUG: Calcineurin Inhibitors (CNI)|DRUG: Mycophenolate acid (MPA)/Azathioprine (AZA)|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Deficiency in Adolescent Girls
Status: COMPLETED
Conditions: Healthy|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: ergocalciferol|OTHER: placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications
Status: COMPLETED
Conditions: Status Epilepticus
Interventions: DRUG: Intramuscular route of active treatment|DRUG: Intravenous route of active treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microsurgical Resection of Intramedullary Spinal Cord Metastases
Status: RECRUITING
Conditions: Spinal Cord Metastasis|Spinal Cord Tumor Malignant Intramedullary|Functional Outcome|Radiotherapy; Complications|Spinal Cord Neoplasms
Interventions: PROCEDURE: Microsurgical resection of ISCM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Evaluate the Efficacy of Capsimax on Metabolic Rate
Status: COMPLETED
Conditions: Metabolism
Interventions: OTHER: Capsimax|OTHER: Micro Crystalline Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Esmolol vs. Labetalol in Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: Labetalol|DRUG: Esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Carotuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Advanced Thyroid Cancer
Status: COMPLETED
Conditions: Recurrent Thyroid Gland Carcinoma|Stage III Differentiated Thyroid Gland Carcinoma AJCC v7|Stage III Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v7|Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v7|Stage IVA Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVB Differentiated Thyroid Gland Carcinoma AJCC v7|Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v7|Stage IVB Thyroid Gland Medullary Carcinoma AJCC v7|Stage IVC Differentiated Thyroid Gland Carcinoma AJCC v7|Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v7|Stage IVC Thyroid Gland Medullary Carcinoma AJCC v7|Thyroid Gland Anaplastic Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2157299 in Participants With Pancreatic Cancer That is Advanced or Has Spread to Another Part of the Body
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: LY2157299|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Escitalopram Genomic Device by Using Candidate Gene Approach and Genome-Wide Scanning
Status: UNKNOWN
Conditions: Depression|Continuous Antidepressant Abuse|Adverse Reaction to Drug
Interventions: DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficiency of Hydroxychloroquine on the Endothelial Dysfunction and Its Vascular Consequences During the Antiphospholipid Syndrome
Status: UNKNOWN
Conditions: Antiphospholipid Syndrome (APS)
Interventions: DRUG: Hydroxychloroquine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Lung Cancer|Non-Small Cell Lung Cancer|Adenocarcinoma of Lung
Interventions: DRUG: LMB-100|DRUG: pembrolizumab|DIAGNOSTIC_TEST: Mesothelin Expression|DIAGNOSTIC_TEST: TrueSight Oncology 500
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin or ImmunoTHerapy in Association With Definitive Radiotherapy in HPV-related oropharyngEal Squamous Cell Carcinoma: a Randomized Phase II Trial.
Status: COMPLETED
Conditions: Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Chemoradiotherapy arm|DRUG: Immunotherapy + Radiotherapy arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Safe, Tolerable and Capable of Producing an Immune Response is, a Modified RNA Vaccine Against Pandemic Influenza
Status: RECRUITING
Conditions: Grippe|Influenza|Vaccines
Interventions: BIOLOGICAL: pdmFlu vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: Licensed influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preventing Postoperative Relapse in Crohn's Disease Patients at Risk: Azathioprine Versus Mesalazine
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Azathioprine|DRUG: Mesalazine|DRUG: Azathioprine placebo|DRUG: Mesalazine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Digital Antimicrobial Stewardship Smartphone Application to Combat AMR: the AB-assistant
Status: UNKNOWN
Conditions: Anti-Infective Agents|Mobile Applications|Quality Improvement|Antimicrobial Stewardship
Interventions: OTHER: AB-assistant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT of Metastases Following Neo-adjuvant Treatment for Colorectal Cancer With Synchronous Liver Metastases
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastasis Colon Cancer
Interventions: RADIATION: stereotactic body radiation treatment (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: simvastatin|DRUG: atorvastatin|DRUG: pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab ozogamicin (GO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bipolar Coagulation Versus Suture Renorrhaphy in Laparoscopic Partial Nephrectomy
Status: COMPLETED
Conditions: Nephrectomy
Interventions: PROCEDURE: laparoscopic partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Muc5ac and Muc2 Mucins in Tear Film Concentration in Surgical Treated Pterygia Patients
Status: COMPLETED
Conditions: Pterygium of Both Eyes
Interventions: PROCEDURE: Amniotic membrane transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: First-line Treatment of Metastatic Pancreatic Cancer With Nab-paclitaxel and Gemcitabine
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer|Adenocarcinoma of the Pancreas
Interventions: DRUG: nab-paclitaxel and gemcitabine|DRUG: gemcitabine mono and nab-paclitaxel and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Farnesyl Transferase Inhibitor (R115777, Tipifarnib) in Patients With Refractory or Relapsed Acute Myeloid Leukemia.
Status: COMPLETED
Conditions: Leukemia, Nonlymphocytic, Acute
Interventions: DRUG: tipifarnib (R115777)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of Midazolam in Human Volunteers
Status: COMPLETED
Conditions: Analgesic Drugs|Antinociceptive Agents
Interventions: DRUG: Midazolam|DRUG: Fentanyl|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
Status: UNKNOWN
Conditions: Duration of Labour
Interventions: DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quadratus Lumborum Block After Cesarean Section: Analgesic Efficacy of Different Concentrations of Local Anesthetics
Status: NOT_YET_RECRUITING
Conditions: Outcome Measures
Interventions: PROCEDURE: QLB procedure after cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Packing Type in Maxillofacial Surgery
Status: COMPLETED
Conditions: Sore Throat|Nausea and Vomiting, Postoperative
Interventions: DRUG: chlorhexidine gluconate %0,12 benzydamine hydrochloride %0,15|OTHER: %0.9 NaCl Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinial Trial of Lutetium [177Lu]-FAP-75 for the Treatment of Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Lutetium [177Lu]-FAP-75
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin
Status: COMPLETED
Conditions: Hepatorenal Syndrome
Interventions: DRUG: Terlipressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COGNITIVE BEHAVIORAL THERAPY PROGRAM TO FIRST-EPISODE PSYCHOSIS PATIENTS AND CANNABIS ABUSE
Status: COMPLETED
Conditions: First-episode Psychosis|Cannabis Abuse
Interventions: BEHAVIORAL: Cognitive-behavioral therapy program to first-episode psychosis patients and cannabis abuse|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients
Status: UNKNOWN
Conditions: Acute Liver Failure|Acute-On-Chronic Liver Failure
Interventions: COMBINATION_PRODUCT: LifeLiver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT