pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Fast-track Clinical Pathway on Minimally-invasive Total Hip Arthroplasty Surgery in NTUH
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: ERAS for MIS-THA|PROCEDURE: conventional MIS-THA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability Study of Ramipril 10 mg Capsules Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Ramipril 10 mg Capsule (Sandoz)|DRUG: Altace (Ramipril) 10 mg Capsule (Aventis Pharmaceutical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study (Double-Blind) of MRA for Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MRA(Tocilizumab)|DRUG: MRA placebo|DRUG: MTX|DRUG: MTX placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NIVOLUMAB Plus IPILIMUMAB and TEMOZOLOMIDE in Microsatellite Stable, MGMT Silenced Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Temozolomide|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis in Treating Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: remote ischemic conditioning|DEVICE: sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Primary Open Angle Glaucoma
Interventions: DRUG: VISION5 Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Urinary Track Infection Prevention After Urogynecological Surgery
Status: COMPLETED
Conditions: Urinary Tract Infections|Urinary Retention Postoperative|Pelvic Organ Prolapse
Interventions: DRUG: Methenamine Hippurate 1 g tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Conventional Double-lumen Tube vs VivaSight DL
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: VivaSight DL|DEVICE: conventional double-lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Clinical Pilates Exercises İn Desk-Based Workers With Sagital Cervical Disorientation
Status: COMPLETED
Conditions: Sagital Cervical Disorientation
Interventions: OTHER: clinical pilates exercises|OTHER: home exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases
Status: UNKNOWN
Conditions: Unresectable Colorectal Liver Metastases
Interventions: DRUG: Chemotherapy|PROCEDURE: Radiofrequency ablation (RFA)|DRUG: In situ immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Usual care|BEHAVIORAL: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Status: ACTIVE_NOT_RECRUITING
Conditions: Geographic Atrophy
Interventions: DRUG: Danicopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma
Interventions: DRUG: Temozolomide|RADIATION: hypofractionated radiation therapy|BIOLOGICAL: bevacizumab|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Relative Bioavailability of PPI-668 New Tablet Versus Capsule Formulations
Status: COMPLETED
Conditions: Pharmacokinetic Assessments in Healthy Volunteers
Interventions: DRUG: PPI-668 tablet|DRUG: PPI-668 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: RADIATION: Stereotactic Radiation|DRUG: Zimberelimab|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elixir Medical Evaluation of the DESolve® Novolimus Eluting Bioresorbable Coronary Scaffold System - Cx Registry
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: DESolve Cx drug eluting coronary scaffold system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Function and Vitamin D Supplementation in Diabetes.
Status: COMPLETED
Conditions: Diabetes Complications|Vitamin D Deficiency|Vitamin D Supplementation|Myocardial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Foot Muscle Energy Technique in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: OTHER: Foot Muscle Energy Technique|OTHER: Conventional Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Equity Evaluation of Fact Boxes on Informed COVID-19 and Influenza Vaccination Decisions - Study Protocol
Status: RECRUITING
Conditions: COVID-19|Influenza
Interventions: OTHER: Fact box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study on Implants With TiUltra Technology and Associated Prosthetic Components
Status: RECRUITING
Conditions: Marginal Bone Level Change
Interventions: DEVICE: NobelActive TiUltra implant|DEVICE: NobelParallel CC TiUltra implants|DEVICE: NobelReplace CC TiUltra implants|DEVICE: Nobel Biocare N1 TiUltra TCC implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RSV001 - A New Vaccine to Prevent Severe Viral Chest Infections.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: PanAd3-RSV given intra-nasally (high dose)|BIOLOGICAL: MVA-RSV given by intra-muscular injection (high dose)|BIOLOGICAL: PanAd3-RSV given by intra-muscular injection (high dose)|BIOLOGICAL: PanAd3-RSV given intranasally (low dose)|BIOLOGICAL: MVA-RSV given by intra-muscular injection (low dose)|BIOLOGICAL: PanAd3-RSV given by intra-muscular injection (low dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Poziotinib in Stage IV Lung Adenocarcinoma With HER2 Mutation (KASTT001)
Status: COMPLETED
Conditions: HER2 Gene Mutation|Adenocarcinoma Lung Stage IV
Interventions: DRUG: Poziotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga/Pranayama for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Pranayama assisted trauma-focused Cognitive Behavioral Therapy (TF-CBT)|BEHAVIORAL: Trauma-focused Cognitive Behavioral Therapy (TF-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of ECT vs. KETAMINE Over the Lifespan
Status: ENROLLING_BY_INVITATION
Conditions: Acute Suicidal Depression (ASD)
Interventions: DRUG: Subanesthetic dose intravenous ketamine (KET)|DEVICE: Electroconvulsive therapy (ECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety & Efficacy of d-Amphetamine Transdermal System vs Placebo in Children & Adolescents With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: d-Amphetamine Transdermal Patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease
Status: RECRUITING
Conditions: Cirrhosis, Liver|End Stage Liver DIsease|Symptoms and Signs|Physical Inactivity|Muscle Loss
Interventions: BEHAVIORAL: LiverWatch Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Long-term Safety of Fezolinetant Given to Japanese Women Going Through Menopause
Status: RECRUITING
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia
Status: TERMINATED
Conditions: Pneumonia, Bacterial|Community-Acquired Infections|Nosocomial Infection|Pneumonia, Ventilator-Associated
Interventions: DRUG: Cefepime placebo|DRUG: Cefepime|DRUG: Doripenem|DRUG: Doripenem placebo|DRUG: Amoxicillin/clavulanate potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and Healthy Volunteers
Status: COMPLETED
Conditions: Diagnostic Imaging
Interventions: DRUG: Bombesin (68Ga) labeled (BAY86-7548)|DRUG: Bombesin (68Ga) labeled (BAY86-7548)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Fecal Microbiota Transplantation in Slow Transit Constipation
Status: UNKNOWN
Conditions: Slow Transit Constipation
Interventions: PROCEDURE: Fecal microbiota transplantation (FMT)|DRUG: Vancomycin and bowel lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Different Doses Of UK-453, 061 Plus Truvada Compared To Efavirenz Plus Truvada In Patients Who Have Not Been Previously Treated For HIV-1
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: UK-453, 061|DRUG: UK-453, 061|DRUG: EFV +TVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate Educational Programs to Improve Fecal Incontinence Care in Nursing Homes
Status: COMPLETED
Conditions: Fecal Incontinence|Staffs' Attitudes
Interventions: BEHAVIORAL: Educational and counselling program|BEHAVIORAL: Educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery
Status: COMPLETED
Conditions: Hand Osteoarthritis|Trigger Finger|Carpal Tunnel Syndrome
Interventions: DRUG: Lidocaine|DRUG: Corticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Study of Retigabine Immediate Release (IR) as Adjunctive Therapy in the Treatment of Adults With Partial-Onset Seizures (POS)
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Retigabine IR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Genital Tract Microflora in Women With Systemic Lupus Erythematosus (SLE) and Immunoglobulin A (IgA) Nephropathy.
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Immunoglobulin A Nephropathy
Interventions: DIAGNOSTIC_TEST: Smear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VNRX-9945 Safety and Pharmacokinetics in Healthy Adult Volunteers
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: VNRX-9945|DRUG: Placebo for VNRX-9945
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Tamsulosin and avanafil|DRUG: Doxazosin and avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate 5 μg/kg Tbo-filgrastim in Infants, Children and Adolescents With Solid Tumors Without Bone Marrow Involvement
Status: COMPLETED
Conditions: Neutropenia
Interventions: DRUG: tbo-filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of AB-101 in Breast Cancer Survivors
Status: COMPLETED
Conditions: Sexual Dysfunction|Sexual Arousal Disorder|Sexual Dysfunction, Physiological|Breast Cancer|Nipple Disorder|Neuropathy|Cancer of Breast
Interventions: DRUG: AB-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-protein High-fiber Diet in Patients With Autoimmune Hepatitis
Status: COMPLETED
Conditions: Autoimmune Hepatitis|Cirrhosis
Interventions: DIETARY_SUPPLEMENT: High protein high fiber diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of High-Intensity Focused Ultrasound (HIFU) Treatment on Fecal Continence and Anorretal Fisiology
Status: COMPLETED
Conditions: Anal Continence After High-Intensity Focused Ultrasound (HIFU) Treatment
Interventions: DIAGNOSTIC_TEST: Anal Manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Back Pain Management in AIS: Yoga vs Physical Therapy
Status: NOT_YET_RECRUITING
Conditions: Scoliosis Idiopathic Adolescent Treatment|Scoliosis Idiopathic|Scoliosis; Adolescence|Scoliosis
Interventions: OTHER: Observation|OTHER: Physical Therapy|OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute|Stroke|Stroke, Cardiovascular|Stroke (CVA) or TIA|Stroke/Brain Attack
Interventions: BEHAVIORAL: Group Lifestyle Balance for People Post Stroke (GLB-CVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)
Status: RECRUITING
Conditions: Brain Metastases
Interventions: DRUG: Niraparib|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal Administration
Status: COMPLETED
Conditions: Management of Chronic Pain
Interventions: DRUG: Hydromorphone Hydrochloride|DEVICE: Programmable Implantable pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Extra-fine Hydrofluoroalkane-beclomethasone Dipropionate (HFA-BDP) Suppress Small Airways Inflammation in Chronic Obstructive Pulmonary Disease (COPD)?
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: HFA-BDP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meperidine for Patients Expected to Have Poor Tolerance During Diagnostic Esophagogastroduodenoscopy.
Status: COMPLETED
Conditions: Patients Undergoing Diagnostic EGD
Interventions: DRUG: placebo|DRUG: Meperidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of Sirolimus and MMF on Vascular Function and Markers of Cellular Function in Renal Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: sirolimus (drug), mmf (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
Status: COMPLETED
Conditions: Post Caesarean Analgesia
Interventions: DRUG: ropivacaine infiltration|DRUG: intrathecal morphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gelesis100 on the Pharmacokinetics of Metformin
Status: COMPLETED
Conditions: Healthy Overweight Obese
Interventions: DEVICE: Gelesis100|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The INFUSE - Anterior Myocardial Infarction (AMI) Study
Status: COMPLETED
Conditions: Acute Anterior Myocardial Infarction
Interventions: DRUG: Abciximab local infusion|OTHER: No local infusion|PROCEDURE: Thrombus aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 4AP to Delay Carpal Tunnel Release (CTR)
Status: NOT_YET_RECRUITING
Conditions: Compression Neuropathy|Carpal Tunnel Syndrome
Interventions: DRUG: 4-Aminopyridine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Metoclopramide Versus Dexketoprofen Trometamol Versus Metoclopramide+ Dexketoprofen Trometamol in Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: metoclopramide|DRUG: dexketoprofen trometamol|DRUG: metoclopramide+dexketoprofen trometamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease
Status: UNKNOWN
Conditions: Myocardial Infarction|Ischemic Stroke|Stroke|Subarachnoid Haemorrhage|Venous Thrombosis|Transient Ischemic Attack|Stable Angina Pectoris|Unstable Angina|Heart Failure|Peripheral Arterial Disease|Abdominal Aortic Aneurysm
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polycystic Ovary Syndrome - Improving Outcomes
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Moxonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical and Socio-demographic Characteristics of Young People Aged 12 to 25 Consulting on Ambulatory Structures in the Seine Saint-Denis
Status: UNKNOWN
Conditions: Psychosis
Interventions: OTHER: we enrolled ultra-high risk of psychosis (UHR) patient to describe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer.
Status: RECRUITING
Conditions: Lung Cancer|Surgery|Non-small Cell Lung Cancer
Interventions: DRUG: ipilimumab, pembrolizumab, durvalumab, idarubicin, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FMT and Fiber in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome
Interventions: COMBINATION_PRODUCT: Fecal Microbial Transplant|DIETARY_SUPPLEMENT: Fiber|DIETARY_SUPPLEMENT: Cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMS-562086 in the Treatment of Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Pexacerfont|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Additive Effect of Topical Ketorolac on the Management of Diabetic Macular Edema With Intravitreal Bevacizumab
Status: COMPLETED
Conditions: DME
Interventions: DRUG: prescription topical ketorolac in group 1|DRUG: prescription artificial tear in group 2|DRUG: prescription topical ketorolac in group 2|DRUG: prescription artificial tear in group1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Safety Of Combo Formulation In The Treatment Of Multiple Episodes Of Acute Migraine Over 12 Months
Status: COMPLETED
Conditions: Migraine Headaches
Interventions: DRUG: Sumatriptan and Naproxen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Software Refraction With Mobilerone Versus Retinoscopy
Status: RECRUITING
Conditions: Myopia|Myopia, Moderate|Astigmatism
Interventions: DEVICE: Software refraction with Eye Test Technology in a mobilerone|DEVICE: Retinoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Effectiveness Study of the Sinovac's Adsorbed COVID-19 (Inactivated) Vaccine
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Adsorbed COVID-19 (Inactivated) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cancer and Blood Pressure Management, CARISMA Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Disorder|Chronic Kidney Disease|Metastatic Renal Cell Carcinoma|Metastatic Thyroid Gland Medullary Carcinoma|Stage IV Renal Cell Cancer AJCC v8|Stage IV Thyroid Gland Medullary Carcinoma AJCC v8|Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8|Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8|Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8
Interventions: OTHER: Best Practice|OTHER: Blood Pressure Measurement|OTHER: Clinical Management|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expressive Writing on Minority Stressors Among Sexual Minority Veterans
Status: RECRUITING
Conditions: Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: Expressive Writing on Minority Stressors|BEHAVIORAL: Neutral Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPT-CAD Score GUIded Dual ANtiplatelet De-esCalation Time
Status: NOT_YET_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: standard DAPT|DRUG: OPT-CAD score guided DAPT de-escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLC
Status: TERMINATED
Conditions: Nonsmall Cell Lung Cancer
Interventions: DRUG: Apatinib/docetaxel/pemetrexed|DRUG: docetaxel/pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Algipore and Decalcified Freeze-dried Bone Allograft in Open Maxillary Sinus Augmentation
Status: COMPLETED
Conditions: Disorder of Maxillary Sinus|Maxillary Sinus Floor Augmentation
Interventions: PROCEDURE: Open Sinus Lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synthetic Cartilage Implant Versus Interposition Arthroplasty in Hallux Rigidus Treatment: A Randomized Clinical Trial
Status: WITHDRAWN
Conditions: Hallux Rigidus
Interventions: PROCEDURE: Hallux Rigidus Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Non-rebreather Mask With the Double-trunk Mask
Status: COMPLETED
Conditions: Hypoxemia
Interventions: DEVICE: Double-Trunk Mask|DEVICE: Non-Rebreather mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 35RC17_8826_NEPHROPAIN Phase APRES : Interest of the Equimolar Oxygen Nitride Mixture (MEOPA) in the Treatment of Pain in Patients Presenting to the Emergency Department for Suspected Renal Colic: a Study BEFORE AFTER
Status: COMPLETED
Conditions: Renal Colic
Interventions: DRUG: MEOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Yoga on Women With Breast Cancer
Status: RECRUITING
Conditions: Upper Limb Functions|Sleep Quality|Upper Limb Muscle Strength|Shoulder Mobility|Heart Rate Variability|Mood|Health-related Quality of Life
Interventions: OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tiragolumab and Atezolizumab in Advanced Pan-cancer Patients
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: Tiragolumab|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Dexchlorpheniramine and Dexchlorpheniramine/Pseudoephedrine/Guaifenesin in Respiratory Infections
Status: UNKNOWN
Conditions: Viral Infections of the Upper Respiratory Tract
Interventions: DRUG: Dexchlorpheniramine, pseudoephedrine, guaifenesin|DRUG: Dexchlorpheniramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Adjunctive Chemomechanical Therapy With Standard Care in Patients With Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: Perisolv (A)|OTHER: Standard (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motivating Increases in Physical Activity for Prevention of Weight Regain After Metabolic Bariatric Surgery
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy-Based Physical Activity Intervention|BEHAVIORAL: Physical Activity Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIIB107 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BIIB107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Salvage Treatment With Gemcitabine and S-1 Combination in Patients With Heavily Treated Advanced Colorectal Cancer.
Status: COMPLETED
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: Gemcitabine/S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Orforglipron|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Dexamethasone in the Conservative Treatment of Chronic Subdural Hematoma
Status: TERMINATED
Conditions: Hematoma, Subdural, Chronic
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety/Efficacy Study of a Non-steroid, Topical Cream Treatment of Psoriasis Over 12-weeks
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: WBI-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension Due to Lung Diseases and Hypoxia|Pulmonary Hypertension|Interstitial Lung Disease
Interventions: OTHER: Prospective study assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeted Breast Milk Fortification for Very Low Birth Weight Infants in the NICU
Status: TERMINATED
Conditions: Human Milk|Neonate|Breast Milk
Interventions: DIETARY_SUPPLEMENT: Targeted Fortification|DEVICE: The Miris Human Milk Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARC041: Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated Liposarcoma
Status: RECRUITING
Conditions: Advanced Dedifferentiated Liposarcoma
Interventions: DRUG: Abemaciclib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Immediate Effect Of Shockwave Therapy On the Quadratus Lumborum (QL) Muscle Trigger Points vs Regular Back Exercises in Chronic Nonspecific Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain, Mechanical
Interventions: DEVICE: shockwave machine|OTHER: leg and back exercises|COMBINATION_PRODUCT: shockwave and exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gut Health and Probiotics in Parkinson's (SymPD)
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Multi-strain probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis|Pain|Fatigue|Cognitive Decline|Depression|Brain Diseases|Hand Rheumatism
Interventions: DRUG: TNF-α inhibitor OR JAK inhibitor|OTHER: Hand training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total/Subtotal Colectomy in Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Secondary Malignant Neoplasm of Large Intestine
Interventions: PROCEDURE: Total or Subtotal Colectomy|PROCEDURE: Other Bowel Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravenous Adenosine Infusion With Regadenoson Bolus for Inducing Maximal Coronary Hyperemia
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: adenosine|DRUG: regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin E Polyethylene in Semented Cups
Status: COMPLETED
Conditions: Total Hip Arthroplasty (THA)
Interventions: DEVICE: Prosthesis component (acetabular cup) E1 cup|DEVICE: Prosthesis component (acetabular cup) Marathon cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: TAPB vs. Caudal for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Status: COMPLETED
Conditions: Anesthesia, Recovery Period
Interventions: PROCEDURE: Caudal Epidural|PROCEDURE: Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
Status: RECRUITING
Conditions: Blood Pressure
Interventions: DIETARY_SUPPLEMENT: magnesium glycinate supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Acidophilus and Bifidobacterium Animalis Subsp. Lactis, Maintenance Treatment in Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: lactobacilus acidophilus & bifidobacterium animalis/lactis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Staccato Apomorphine Single and Multi Dose PK
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: 009-1|DRUG: active comparator|DRUG: 009-0|DRUG: 009-2|DRUG: 009-3|DRUG: 009-4|DRUG: 009-5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial
Status: SUSPENDED
Conditions: Septic Shock
Interventions: COMBINATION_PRODUCT: Standard medical therapy|DEVICE: Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 12 hours|DEVICE: Standard medical therapy plus cytokine removal treatment using Cytosorb, with the adsorber changed in every 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Cerclage for Twin Pregnancy With Shortened Cervix
Status: RECRUITING
Conditions: Preterm Birth|Twin Pregnancy With Antenatal Problem|Cervical Shortening
Interventions: PROCEDURE: cervical cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids
Status: COMPLETED
Conditions: Dystrophinopathy|Duchenne Muscular Dystrophy|Becker's Muscular Dystrophy
Interventions: DRUG: L-arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Sensory Stimulation to Enhance Hand Function Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Vibration|OTHER: Placebo (for vibration)|BEHAVIORAL: therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Rapastinel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Severe Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Cyclosporine A|DRUG: ATG|DRUG: MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Contraceptive Counseling During Pregnancy
Status: RECRUITING
Conditions: Contraception|Intrauterine Device|Contraceptive Implant|Long-acting Reversible Contraception|Counseling
Interventions: OTHER: Structured contraceptive counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Trivalent and Bivalent (Types 1 & 2) Novel Oral Poliomyelitis Vaccines
Status: NOT_YET_RECRUITING
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Novel oral poliomyelitis vaccine type 1 (nOPV1)|BIOLOGICAL: Novel oral poliomyelitis vaccine type 2 (nOPV2)|BIOLOGICAL: Novel oral poliomyelitis vaccine type 3 (nOPV3)|BIOLOGICAL: Bivalent Oral Poliomyelitis Vaccine (bOPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Muscle Spasticity
Interventions: DEVICE: Low-magnitude vibration|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ITT-5 Mechanisms of Spermatogenesis in Man
Status: WITHDRAWN
Conditions: Gonadotropin Deficiency
Interventions: DRUG: Testosterone 1% Gel|DRUG: Acyline|DRUG: Dutasteride|DRUG: Ketoconazole|DRUG: HCG|DRUG: placebo dutasteride|DRUG: placebo ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Long Term Cyclic Testosterone Administration on Muscle Function and Bone in Older Men
Status: WITHDRAWN
Conditions: Sarcopenia
Interventions: DRUG: Testosterone enanthate|DRUG: Testosterone enanthate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Simultaneous Application of HD-tDCS and Robot-assisted Gait Training on Gait Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Brain stimulation|DEVICE: Treadmill gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIFU Ablation of Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|Desmoid; Abdominal
Interventions: DEVICE: High Intensity Focused Ultrasound Ablation|DIAGNOSTIC_TEST: Tumour Biopsy and Venous Blood Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A
Status: UNKNOWN
Conditions: Hypercholesterolemia|Thrombosis
Interventions: DRUG: Clopidogrel|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDL-1 Targeting in Resectable Oesophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer, Stage II|Esophageal Cancer Stage III
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiotherapy 23 x 1.8 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Neck Treatment on Shoulder Impingement
Status: TERMINATED
Conditions: Shoulder Impingement|Shoulder Pain|Rotator Cuff Tendinitis|Cervical Degenerative Joint Disease
Interventions: PROCEDURE: shoulder treatment|PROCEDURE: Shoulder AND cervical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Status: UNKNOWN
Conditions: Renal Stone
Interventions: PROCEDURE: percutaneous nephrolithotomy for kidney stones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Ca Absorption and Tolerance in Healthy Term Infants Fed Milk-based Formulas With Different Fat Blends
Status: COMPLETED
Conditions: Infant
Interventions: OTHER: Infant Formula milk based|OTHER: Infant formula milk based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tranexamic Acid (TXA) on Visualization During Shoulder Arthroscopy
Status: UNKNOWN
Conditions: Shoulder Arthroscopy|Operative Bleeding|Postoperative Pain
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical Analysis
Status: NOT_YET_RECRUITING
Conditions: Oral Lichen Planus
Interventions: DRUG: 6-Gingerol|DRUG: Triamcinolone Acetonide 0.1% Oromucosal Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy.
Status: COMPLETED
Conditions: Palliative Care|Pain|Cancer
Interventions: DRUG: Sativex Low Dose|DRUG: Sativex Medium Dose|DRUG: Sativex High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus a Two-course Treatment With Urea 40% Ointment and Bifonazole Cream 1%
Status: COMPLETED
Conditions: Foot Dermatoses
Interventions: DRUG: Loceryl Nail Lacquer|DRUG: Urea Ointment|DRUG: Bifonazole Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Lymph Node Imaging in Prostate Cancer: PSMA PET-CT and Nano-MRI
Status: UNKNOWN
Conditions: Prostate Cancer|Lymph Node Metastases
Interventions: DIAGNOSTIC_TEST: Ferumoxtran-10 enhanced MRI; MRI contrast agent|DIAGNOSTIC_TEST: 68Ga PSMA PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC