pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery
Status: RECRUITING
Conditions: Coronary Artery Bypass Grafting|Postoperative Atrial Fibrillation|Coronary Artery Disease
Interventions: DRUG: Bisoprolol|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home Assessment and Initiation of Antiretroviral Therapy for HIV in Malawi
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: Home assessment and initiation of ART|OTHER: Clinic-based ART assessment and initiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A 24-week Study to Evaluate the Efficacy and Safety of GSK573719/GW642444 125/25 mcg and 62.5/25mcg Inhalation Powder Compared With Placebo in Subjects With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719/VI 62.5/25|DRUG: GSK573719/VI 125/25|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Recurrent Ulcer Bleeding in Arthritis Patients Using Esomeprazole Plus Celecoxib
Status: COMPLETED
Conditions: Arthritis|Bleeding Ulcer
Interventions: DRUG: celecoxib, esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy
Status: COMPLETED
Conditions: Cat Allergy|Cat Hypersensitivity
Interventions: DRUG: Cat-PAD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT for the Quantification of Atherosclerotic Plaque Inflammation
Status: UNKNOWN
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: OTHER: [18F]-FDG positron emission computed tomography|PROCEDURE: Invasive coronary angiography|PROCEDURE: Intravascular ultrasound and virtual histology|OTHER: Serum biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations
Status: COMPLETED
Conditions: Vaginal Discharge|Perineum; Rupture|Analgesia
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Mepivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Meditation
Status: NOT_YET_RECRUITING
Conditions: Burnout|Compassion Fatigue|Psychological Well-Being
Interventions: BEHAVIORAL: Mindfulness Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virological and Immunological Safety of a Dose Reduction Strategy Antiretroviral Regimen With Efavirenz / Tenofovir / Emtricitabine
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: ATRIPLA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Non-specific Low Back Pain
Interventions: DRUG: VER-01|DRUG: Opioid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Organized Program To Initiate Lifesaving Treatment In Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DRUG: Beta-blockers including Carvedilol|DRUG: ACE inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Botulin Toxin Versus Hyaluronic Acid by Intra-articular Injection for the Treatment of Painful Knee Osteoarthritis
Status: UNKNOWN
Conditions: Painful Unilateral Femorotibial Knee Osteoarthritis of Any Etiology
Interventions: DRUG: Botulinum toxin A ( BoNT-A)|DEVICE: Hyaluronic acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Hydrocortisone|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Desflurane With Sevoflurane for School-age Children in Postoperative Cognitive Function
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction
Interventions: DRUG: Desﬂurane|DRUG: sevoﬂurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer|Papillary Serous Mullerian Tumor|Clear Cell Mullerian Tumor
Interventions: DRUG: bevacizumab|DRUG: erlotinib|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tranilast to Treat Pterygium Before Excision
Status: COMPLETED
Conditions: Pterygium
Interventions: DRUG: Tranilast, and Tissucol|OTHER: Beriplast P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Integration of Supportive Care for Metastatic Uveal Melanoma Patients (EarlyTogether)
Status: RECRUITING
Conditions: Uveal Melanoma
Interventions: OTHER: Supportive care visit with questionnaires|OTHER: Oncological standard visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Epilepsy
Interventions: DRUG: Eslicarbazepine acetate (BIA 2-093)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Erlotinib, Gemcitabine and Oxaliplatin Combination Chemotherapy to Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Erlotinib|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lixisenatide on the Effect of Pituitary Hormones
Status: RECRUITING
Conditions: Healthy|Type 1 Diabetes
Interventions: DRUG: Placebo|DRUG: Lixisenatide 10 micrograms (50 micrograms/ml in 3 ml) Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Auto-Bolus Interval on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Group I: 30 Min Interval Time|PROCEDURE: Group II: 60 Min Interval Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization
Status: COMPLETED
Conditions: Liver Cancer|Liver Neoplasm|Hepatocellular Carcinoma|HCC
Interventions: DRUG: [18F] FMISO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Atorvastatin on Human Semen and Gonadal Hormones
Status: COMPLETED
Conditions: Healthy Volunteers|Normocholesterolaemic Men|Normozoospermic Men
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P.Vivax Treatment Trial
Status: COMPLETED
Conditions: Plasmodium Vivax
Interventions: DRUG: Dihydroartemisinin-piperaquine (DP) + Primaquine (PQ)|DRUG: Dihydroartemisinin-piperaquine (DP) + Primaquine (PQ) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033)
Status: COMPLETED
Conditions: Chronic Cough
Interventions: DRUG: Gefapixant 45 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Use of Coated Venous Catheters in the Critically Ill Child
Status: COMPLETED
Conditions: Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
Interventions: DEVICE: Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Musitox® Project: Consumption of Psychoactive Substances at Music Festivals in Aquitaine
Status: COMPLETED
Conditions: Poisoning by Psychoactive Substances
Interventions: PROCEDURE: Sampling of a few drops of blood, lock of hair and urine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Diabetes Assistant (DiAs) Control-to-Range (CTR) Nocturnal Closed-Loop Camp Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Diabetes Assistant (DiAs)|DEVICE: Tandem t:slim Insulin Pump|DEVICE: Dexcom G4 Platinum sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN
Status: ACTIVE_NOT_RECRUITING
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm|Myeloproliferative Neoplasm
Interventions: DRUG: IMGN632
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Inactivated Influenza Vaccine (0.5ml Formulation)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza split vaccine of 15 μg HA|BIOLOGICAL: Influenza split vaccine of 15 μg HA|BIOLOGICAL: Influenza split vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Neuropsychological Characterization of Social Feedback Processing in Social Anxiety
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Social feedback|BEHAVIORAL: Self-referential paradigm|BEHAVIORAL: Reward vs. punishment task|BEHAVIORAL: Emotional reactivity task
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evidence-Based Practice: Proposed Application of Facilitating Tools for Clinical Nurses
Status: COMPLETED
Conditions: Evidence-Based Practice
Interventions: BEHAVIORAL: Educational Workshop|BEHAVIORAL: Educational Workshop plus J. H. N. EBP Guide Tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Adult Participants With BRAF V600 Mutation-Positive Advanced Melanoma Treated With Cobimetinib (Cotellic®) During the French Early Access Program (Temporary Authorization for Use [TAU])
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Cobimetinib|DRUG: Vemurafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition
Status: COMPLETED
Conditions: Coronary Artery Disease|Drug Resistance
Interventions: DRUG: Adjustment of clopidogrel dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regional Differences of Cutaneous Irritation and Its Effect on Skin Barrier Recovery
Status: COMPLETED
Conditions: Irritant Contact Dermatitis
Interventions: PROCEDURE: Sodium lauryl sulphate induced irritation|OTHER: Emollient, moisturizing cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome
Status: COMPLETED
Conditions: Amplified Musculoskeletal Pain Syndrome|Reflex Sympathetic Dystrophy|Complex Regional Pain Syndromes
Interventions: DEVICE: Oculus GO VR HMD, application Happy Place (© Mimerse)|DEVICE: iPad, application Happy Place (© Mimerse)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Perceptual Learning Based Digital Therapeutics for Stereopsis in Intermittent Exotropia
Status: RECRUITING
Conditions: Intermittent Exotropia
Interventions: DEVICE: Nu.T|OTHER: No-Treatment Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stimulation and Validation of the Pupillary Dilation for the Detection of Pain in Analgosedated Patients Under Mechanically Ventilation in Intensive Care Unit
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: Pupillometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
Status: COMPLETED
Conditions: Uterine Myoma|Ovarian Cyst|Laparoscopic Gynecologic Surgery
Interventions: PROCEDURE: conventional I:E ratio|PROCEDURE: 1:1 ratio|PROCEDURE: 2:1 group|PROCEDURE: external PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Trimetrexate glucuronate|DRUG: Pentamidine isethionate|DRUG: Sulfamethoxazole-Trimethoprim|DRUG: Leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Combined Lactobacilli (Reuteri LMG P-27481 and GG ATCC 53103) to Prevent Antibiotic Associated Symptoms in Children
Status: UNKNOWN
Conditions: Diarrhea Caused by Drug|Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: combined Lactobacilli|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Resistant Starch in a Baked Snack Bar on a Post-prandial Glycemic and Insulinemic Response
Status: UNKNOWN
Conditions: Hyperglycemia, Diabetes, and Obesity
Interventions: DIETARY_SUPPLEMENT: Resistant starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain
Status: RECRUITING
Conditions: Opioid-induced Constipation
Interventions: DRUG: Naldemedine|DRUG: Lubiprostone|DRUG: Naloxegol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Nonmalignant Hematologic Disease
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: methylprednisolone|PROCEDURE: umbilical cord blood transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Xaliproden (SR57746A) in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: xaliproden (SR57746A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure.
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine Sequential Treatment for Endometriosis Associated Infertility
Status: UNKNOWN
Conditions: Endometriosis|Infertility
Interventions: DRUG: pre-ovulation Decoction|DRUG: post-ovulation Decoction|DRUG: pre-ovulation Decoction(placebo)|DRUG: post-ovulation Decoction(placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor
Status: RECRUITING
Conditions: Sleep-Disordered Breathing|Sleep Architecture|Arrhythmia
Interventions: DEVICE: Belun Ring|DEVICE: Belun Cor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Insulin Glargine/Insulin Glulisine Regimen to Insulin Aspart/Insulin Aspart Protamine 30/70 in Type 2 Diabetes Mellitus Patients (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE|DRUG: INSULIN GLULISINE|DRUG: Insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening
Status: COMPLETED
Conditions: Lung Cancer|Smoking Cessation|Tobacco Use Cessation
Interventions: BEHAVIORAL: Patient Decision Aid|BEHAVIORAL: Standard Educational Information|BEHAVIORAL: Follow-Up Assessments: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Clarithromycin and Rifampicin on the Pharmacokinetics of XZP-3287 in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: XZP-3287 combined with clarithromycin|DRUG: XZP-3287 combined with rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Rehabilitation in MS Patients
Status: RECRUITING
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: OTHER: Computerized cognitive rehabilitation|OTHER: Sham placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3381916 Alone or in Combination With LY3300054 in Participants With Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Non Small Cell Lung Cancer|Renal Cell Carcinoma|Triple Negative Breast Cancer
Interventions: DRUG: LY3381916|DRUG: LY3300054
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old
Status: RECRUITING
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Acute Myeloid Leukemia With Myelodysplasia-Related Changes|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Liposome-encapsulated Daunorubicin-Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transpulmonary Driving Pressure and Intra-abdominal Pressure Relationship During Laparoscopic Surgery
Status: COMPLETED
Conditions: Anesthesia, General/Methods|Laparoscopy|Respiration, Artificial|Positive-Pressure Respiration|End-Expiratory Pressure, Positive|Ventilator-Induced Lung Injury
Interventions: OTHER: Standard PEEP ventilation|OTHER: Matched PEEP ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of ActiveMatrix on Spinal SSI Rate
Status: NOT_YET_RECRUITING
Conditions: Spinal Stenosis Lumbar|Surgical Site Infection|Back Pain Lower Back Chronic
Interventions: DRUG: ActiveMatrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Utilization of a Peer-Based Approach for the Promotion of Physical Activity in Inactive Women
Status: RECRUITING
Conditions: Obesity-Related Malignant Neoplasm
Interventions: DEVICE: Activity Monitor|DEVICE: Activity Monitor|OTHER: Educational Intervention|OTHER: Survey Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intra-arterial Chemotherapy for Children With Retinoblastoma
Status: UNKNOWN
Conditions: Retinoblastoma
Interventions: DRUG: Intra-arterial injection of melphalan|DRUG: Injection of melphalan into the ophthalmic artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Cyclodynon on Reducing the Cumulative Risk of Breast Cancer Development in a Female Aged 40-52
Status: UNKNOWN
Conditions: Mammographic Breast Density
Interventions: DRUG: Cyclodynon|BEHAVIORAL: Lifestyl modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Immunogenicity of GSK Bio's Influenza Vaccine GSK576389A After Repeated Vaccination in Elderly Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™|BIOLOGICAL: GSK Bio's Influenza Vaccine GSK576389A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ToleroMune Ragweed Exposure Chamber Study
Status: COMPLETED
Conditions: Ragweed Allergy
Interventions: BIOLOGICAL: ToleroMune Ragweed|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Contraceptive Efficacy and Safety of a Subdermal Etonogestrel Implant (Implanon®)(P06473)(COMPLETED)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: etonogestrel implant (Implanon)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thinking Skills for Work in Severe Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Major Depression|Bipolar Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: Thinking Skills for Work Program|BEHAVIORAL: Supported Employment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Endothelial and Vascular Functions in Obese Patients (FUENVASOB)
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Passive knee flexion-extension + Cycle ergometer exercise + 3-week body weight reduction program|OTHER: Passive knee flexion-extension + Cycle ergometer exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository
Status: RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma, H3 K27M-Mutant|Diffuse Midline Glioma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High-Intensity Interval Training and Intermittent Fasting on Body Composition and Physical Performance in Active Women
Status: COMPLETED
Conditions: Body Composition|Physical Performance|Intermittent Fasting
Interventions: BEHAVIORAL: Intensity interval training (HIIT)|BEHAVIORAL: Intensity interval training (HIIT) + intermittent fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Levodopa for the Treatment of Residual Amblyopia
Status: COMPLETED
Conditions: Amblyopia
Interventions: DRUG: Levodopa/Carbidopa|DRUG: Placebo|OTHER: Patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of ZIO-101 in Advanced Blood and Bone Marrow Cancers
Status: COMPLETED
Conditions: Hematologic Neoplasms|Bone Marrow Neoplasms|Non-Hodgkin's Lymphoma
Interventions: DRUG: Darinaparsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.
Status: UNKNOWN
Conditions: Gingival Recession|Tooth Abrasion
Interventions: PROCEDURE: MCAF|PROCEDURE: PR|PROCEDURE: CTG|PROCEDURE: XMD(Mucoderm®)|DRUG: Sodium dipyrone|DRUG: chlorhexidine rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of 3D Printed Models of Aortic Stenosis in Guiding TAVI Procedure
Status: UNKNOWN
Conditions: Aortic Stenosis|Valvular Cardiomyopathy|Aortic Valve Disease
Interventions: DIAGNOSTIC_TEST: Cardiac imaging|DEVICE: 3D printing of the aortic valve
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Interrupted vs Continuous Suturing Techniques for Radiocephalic Fistulae
Status: UNKNOWN
Conditions: End Stage Renal Failure
Interventions: PROCEDURE: Interrupted|PROCEDURE: Continuous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Etanercept Regimens (REUMATOCEPT® Versus ENBREL®) for Treatment of Rheumatoid Arthritis
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Reumatocept (etanercept)|DRUG: Enbrel (etanercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Cognition in Older Adults With Intermittent Hypoxia and Cognitive Training
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Acute Intermittent Hypoxia|BEHAVIORAL: Computerized Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm^2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (EXTRA)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1
Status: RECRUITING
Conditions: Advanced Solid Tumor|Non-small Cell Lung Cancer|Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: MT-6402
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate MEDI-507 in Patients With CD2-Positive Lymphoma/Leukemia
Status: TERMINATED
Conditions: Lymphoma|Leukemia|Cancer
Interventions: DRUG: MEDI-507
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for the Evaluation of a GVHD Negative Outcome Score (GNOS) in Matched Unrelated or Haploidentical Hematopoietic Stem Cell Transplant
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Stem Cell Transplantation, Hematopoietic|Transplantation, Hematopoietic Stem Cell
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-561|DRUG: IVA|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copper Cu-64 TP3805 PET/CT in Imaging Patients With Urothelial Cancer Undergoing Surgery or Biopsy
Status: COMPLETED
Conditions: Bladder Urothelial Carcinoma|Urothelial Carcinoma
Interventions: DRUG: Copper Cu 64 TP3805|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Metastatic Prostate Cancer|Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Carboplatin|DRUG: 177Lu-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Retifanlimab|DRUG: INCAGN02385|DRUG: INCAGN02390|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant (F)/Goserelin (G) vs Anastrozole (A)/G vs G for Premenopausal Women
Status: UNKNOWN
Conditions: Metastatic Breast Cancer|Estrogen Receptor Positive Tumor|Breast Cancer Nos Premenopausal
Interventions: DRUG: Fulvestrant plus Goserelin|DRUG: Anastrozole plus Goserelin|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Mobile Health Approach to Reduce Barriers to Cervical Cancer Screening in Tanzania
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BEHAVIORAL: Motivational SMS|BEHAVIORAL: Travel Voucher
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: The Study of Gemcitabine in the Maintenance Treatment of Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: THE Efficacy and Safety of Gemcitabine in the Maintenance Treatment of Advanced Non-small Cell Lung Cancer
Interventions: DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod
Status: RECRUITING
Conditions: Ependymoma
Interventions: BIOLOGICAL: HLA-A2 restricted synthetic tumor antigen|DRUG: Imiquimod|OTHER: enzyme-linked immunosorbent assay|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Exercise on Serum Uncoupling Protein-1 Level and the Role of Uncoupling Protein-1-3826 A/G Polymorphism
Status: COMPLETED
Conditions: Uncoupling Protein-1|Polymorphism, Restriction Fragment Length|Irisin
Interventions: OTHER: Yo-Yo intermittent recovery test (level 1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Bupropion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Doxil in the Treatment of Patients With Refractory Idiopathic Thrombocytopenic Purpura
Status: UNKNOWN
Conditions: Autoimmune Thrombocytopenic Purpura
Interventions: DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATTR Amyloidosis in Elderly Patients With Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis Symptomatic|Amyloidosis Cardiac
Interventions: DIAGNOSTIC_TEST: Tc-99m-DPD scintigraphy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclooxygenase-2 (COX-2) Inhibitor Reduces Serum Prostatic Specific Antigen (PSA) Levels
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Doxazosin 4 mg daily plus Celecoxib 200 mg every day (QD)|DRUG: Doxazosin 4 mg every day (QD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MD-Logic Artificial Pancreas for Automatic Type 1 Diabetes Meals Management
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: MD-bolus calculator for pre-meal bolus|DEVICE: No MD-bolus calculator for pre-meal bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial to Evaluate the Elortinib vs Gefitinib in Advanced NSCLC With EGFR Exon 19 or 21 Mutations
Status: COMPLETED
Conditions: Thoracic Neoplasms
Interventions: DRUG: erlotinib|DRUG: gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Nitazoxanide in Acute Gastroenteritis in Australian Indigenous Children
Status: TERMINATED
Conditions: Gastroenteritis
Interventions: DRUG: Nitazoxanide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of ZX008 in Children and Young Adults With Dravet Syndrome or Lennox Gastaut Syndrome Currently Taking Cannabidiol
Status: COMPLETED
Conditions: Dravet Syndrome|Lennox Gastaut Syndrome
Interventions: DRUG: ZX008 0.2 to 0.8 mg/kg/day|DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Laser Acupuncture on Insomnia in Perimenopausal Women
Status: UNKNOWN
Conditions: Insomnia Type; Sleep Disorder|Perimenopausal Women
Interventions: DEVICE: laser acupuncture|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodality Therapy for Palliative Resectable Hepatocellular Carcinoma With Intrahepatic Vessels Invasion
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Hepatectomy|PROCEDURE: TACE combined with local regional therapies without hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation on the Cortical Communication (CortiCom) System
Status: RECRUITING
Conditions: Tetraplegia|Locked-in Syndrome|Brainstem Stroke|Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Surgical implantation of CortiCom system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of AMCOP Bioactivator and High-pull Headgear in Treating Skeletal Class II Hyperdivergent Pediatric Patients
Status: COMPLETED
Conditions: Skeletal Malocclusion
Interventions: DEVICE: AMCOP group|DEVICE: High-pull headgear
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erbium-doped Yttrium Aluminium Garnet Laser(Er:Yag)Associated With Amorolfine Lacquer in the Treatment of Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis
Interventions: DEVICE: Er:YAG laser + amorolfine lacquer|DRUG: Amorolfine lacquer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the MindMotionPRO for Early Post-stroke Upper-limb Rehabilitation
Status: TERMINATED
Conditions: Stroke|Motor Disorders
Interventions: DEVICE: MindMotionPRO|OTHER: Self-Directed Prescribed Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STAIR for Trauma and Emotion Dysregulation
Status: ENROLLING_BY_INVITATION
Conditions: Posttraumatic Stress Disorder|Borderline Personality Disorder|Emotion Regulation
Interventions: BEHAVIORAL: STAIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Binaural Auditory Beats on Hand-Eye Coordination in Adult Population
Status: RECRUITING
Conditions: Binaural Auditory Beats ,Hand-eye Coordination
Interventions: OTHER: Beta auditory beats (Group A)|OTHER: white noise (Group B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Early Initiation of CGM-Guided Insulin Therapy in Stage 2 T1D
Status: UNKNOWN
Conditions: Type 1 Diabetes|Prediabetic State|Dysglycemia|Autoimmune Diabetes
Interventions: OTHER: Early CGM-guided education and initiation of insulin therapy.|OTHER: Usual care: glucometer surveillance and basic education.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS Associated With Symptom Provocation in the Management of Patients With Resistant Obsessive Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: tDCS + symptoms provocation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Pi Max and Diaphragm Maximum Inspiratory Excursion Detected With Ultrasound During Weaning
Status: WITHDRAWN
Conditions: Weaning|Diaphragm Ultrasound|Maximum Inspiratory Pressure
Interventions: DIAGNOSTIC_TEST: diaphragm ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-term Effects on Tear Film (Baby Shampoo vs Blephasol)
Status: RECRUITING
Conditions: Blepharitis
Interventions: OTHER: Blephaclean|OTHER: Baby Shampoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Immunity to Varicella Zoster Virus After Immunization With V212 Vaccine or Zostavax (V212-003)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: V212|BIOLOGICAL: Comparator: Zostavax™|BIOLOGICAL: Comparator: Placebo|OTHER: VZV Skin Test|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Pain|Physical Activity|Mitochondrial Pathology
Interventions: BEHAVIORAL: Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues
Status: COMPLETED
Conditions: Alcohol Dependance
Interventions: DEVICE: medial prefrontal cortex|DEVICE: dorsolateral prefrontal cortex|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: QAX028|DRUG: QAX028|DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curcumin for Prevention of Relapse in Patients With Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis in Remission
Interventions: DIETARY_SUPPLEMENT: Curcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Non-Invasive Pressure Monitor for Neonates & Infants at Risk of Developing Hydrocephalus
Status: NOT_YET_RECRUITING
Conditions: Hydrocephalus in Infants
Interventions: DEVICE: Non-Invasive Pressure Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genotype-guided Treatment in Newly Diagnosed PTCL
Status: RECRUITING
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: CHOP+selinexor+5-Azacitidine|DRUG: CHOP+duvelisib+5-Azacitidine|DRUG: CHOP+chidamide+tislelizumab|DRUG: standard CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI
Status: COMPLETED
Conditions: Myocardial Infarction|Contrast-induced Nephropathy
Interventions: PROCEDURE: the adequate hydration group guided by Vigileo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topiramate-Phentermine Combinations for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Use Disorder
Interventions: DRUG: Cocaine|DRUG: Placebo|DRUG: Phentermine|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Air Verses Oxygen In myocarDial Infarction Study
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Coronary Artery Disease
Interventions: OTHER: Oxygen therapy|OTHER: No oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guarana (Paullinia Cupana) for Breast Cancer Chemotherapy-related Fatigue
Status: COMPLETED
Conditions: Signs and Symptoms|Neoplasms|Neoplasms by Site|Fatigue|Breast Neoplasms|Breast Diseases
Interventions: DRUG: Guarana extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT