pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Somatosensory Motor Intergration Training on Post-stroke Upper Limb Function.
Status: NOT_YET_RECRUITING
Conditions: Chronic Stroke
Interventions: BEHAVIORAL: somatosensory-motor integration training|BEHAVIORAL: pure somatosensory training|BEHAVIORAL: pure motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mental Imagery and Targeted Memory Reactivation in Insomnia
Status: RECRUITING
Conditions: Insomnia Disorder
Interventions: BEHAVIORAL: Imagery Rescripting (IR)|BEHAVIORAL: Imagery Rescripting (IR) and Targeted Memory Reactivation (TMR) during sleep|BEHAVIORAL: Sleep Hygiene|BEHAVIORAL: Sleep Hygiene + Odor|OTHER: "Rocking bed" if patients still have insomnia complaints (ISI >10) after the 4 weeks of the intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Irinotecan or Bevacizumab and Temozolomide With Concomitant Radiotherapy for Primary Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: bevacizumab and Irinotecan and radiotherapy|DRUG: Bevacizumab and Temozolomide and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zenith Low Profile AAA Endovascular Graft (ZLP) Clinical Study
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm|Aorto-iliac Aneurysm|Iliac Aneurysm
Interventions: DEVICE: ZLP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing the Efficacy of Tenofovir Disoproxil Fumarate/Emtricitabine/Rilpivirine (TDF/FTC/RPV) Versus TDF/FTC/Efavirenz (TDF/FTC/EFV) in Patients With Undetectable Plasma HIV-1 RNA on Current First-line Treatment
Status: COMPLETED
Conditions: Human Immunodeficiency Virus-type 1 Infection
Interventions: DRUG: Rilpivirine|DRUG: Efavirenz|DRUG: Tenofovir disoproxil fumarate|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation Using Transcranial Direct Current Stimulation for Neuropsychiatric Symptoms of Dementia
Status: COMPLETED
Conditions: Dementia; Alzheimer, Mixed Type (Etiology)
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Intervention for Emotional Distress of Insomnia People
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress and Insomnia (MIED-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Depression: From the Clinical Trial, Biomarkers to Molecular Biology
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paula Method Versus Chewing Gum for Postoperative Recovery After Caesarean Section
Status: COMPLETED
Conditions: Cesarean Delivery Affecting Fetus|Post Operative Bowel Function
Interventions: BEHAVIORAL: Paula exercises|BEHAVIORAL: Gum chewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin +/- Nivolumab in Metastatic Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IFPE (Invisalign First Palatal Expander)
Status: NOT_YET_RECRUITING
Conditions: Narrow Maxilla
Interventions: DEVICE: Invisalign first palatal expander|DEVICE: Conventional rapid maxillary expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Design of Couple Counseling and Testing in Antenatal Clinics in Dar es Salaam, Tanzania
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Couples VCT|BEHAVIORAL: Individual VCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Efficacy and Safety of JAK Inhibitor in the Treatment of Anti-MDA5 Antibody-positive Dermatomyositis Patients
Status: UNKNOWN
Conditions: Dermatomyositis, Adult Type
Interventions: DRUG: JAK Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure
Status: COMPLETED
Conditions: Lactating Women
Interventions: DRUG: Lusedra|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Soft and Hard Tissue Changes Around the New Lance® Implants Using Traditional and Switch Platform Abutments
Status: UNKNOWN
Conditions: Group A- 23 Implant Using Switch Platform -SPK Abutment.|Group B- 22 Implant Using the Traditional -CPK Abutment.
Interventions: PROCEDURE: spk|PROCEDURE: CPK Abutments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Belimumab in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Placebo|DRUG: Belimumab 1 mg/kg|DRUG: Belimumab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Office Bleaching Agents in Patients of Different Age Group
Status: COMPLETED
Conditions: Satisfaction
Interventions: DRUG: Hydrogen peroxide 35%|DRUG: Hydrogen peroxide 38%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soft Peripheral Contact Lens for Eye Elongation Control (SPACE):1-year Results of a Double-blinded Randomized Con-trolled Trial
Status: COMPLETED
Conditions: Soft Contact Lens
Interventions: OTHER: soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Motivational, Movement and Self-Management Training for Adolescents in Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: BEHAVIORAL: In-person Motivational Interview combined with Self-Management techniques|BEHAVIORAL: Video-based Motivational Interview combined with Self-Management techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Covered Versus Uncovered Biliary Stents for Biliary Malignancies
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DEVICE: covered biliary stents|DEVICE: uncovered biliary stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: acetominophen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Acupuncture for Impacted Mandibular Third Molar Extractions
Status: UNKNOWN
Conditions: Extraction of Third Molar Teeth
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients
Status: COMPLETED
Conditions: Basal Cell Nevus Syndrome
Interventions: DRUG: Patidegib|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of Freezing-thawing Procedures and the Prolonged Culture of Embryos on Epigenetic Regulation in Humans
Status: COMPLETED
Conditions: Assisted Reproductive Technology|Freezing/Thawing Procedure|Prolonged Culture Procedure
Interventions: OTHER: Sample of cord blood|OTHER: Sample of placenta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Lenzilumab in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: lenzilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cross-Sectional Observational Study on Retained Drug Needle Fragments in People Who Use Intravenous Drugs
Status: RECRUITING
Conditions: Drug Abuse, Intravenous|Substance Dependence|Needle Injury|Soft Tissue Injuries|Foreign Bodies
Interventions: RADIATION: Low-dose X-ray of subcutaneous tissues
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-Dose Gene Replacement Therapy Using for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies
Status: COMPLETED
Conditions: Spinal Muscular Atrophy Type I
Interventions: BIOLOGICAL: Onasemnogene Abeparvovec-xioi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
Status: COMPLETED
Conditions: Dexamethasone Adverse Reaction|Postoperative Pain|Postoperative Thoracic Procedure Complication|Analgesia
Interventions: DRUG: Dexamethasone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
Status: NOT_YET_RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Montelukast 10 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENBD After Endoscopic Sphincterotomy Plus Large-balloon Dilation for Preventing PEP
Status: UNKNOWN
Conditions: Post-ERCP Acute Pancreatitis
Interventions: PROCEDURE: EST+LBD+ENBD|PROCEDURE: EST+LBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: UW Quitting Using Intensive Treatment Study (QUITS)
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Varenicline|DRUG: Nicotine patch|OTHER: Placebo Patch|OTHER: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PET/MR Pre- and Post Radiotherapy for Cardiopulmonary Dysfunction Evaluation
Status: RECRUITING
Conditions: Pulmonary Hypertension
Interventions: DRUG: PET/MR with 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of a Dedicated Geriatric Sector on the Loss of Functional Autonomy at 1 Month for Patients Admitted to Emergencies and Non-hospitalised
Status: COMPLETED
Conditions: Health Services for the Aged|Emergency Service, Hospital|Ambulatory Care
Interventions: OTHER: Activities of Daily Living (ADL) questionnaire (The Katz index )
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: N-Acetylcysteine for Patients With COPD and ChronicBronchitis
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Bronchitis
Interventions: DRUG: N-acetylcysteine|DRUG: Oral acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-programmed Cell Death-1 Ligand 1 (aPDL-1) Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid in Recurrent Platinum Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Bevacizumab|DRUG: atezolizumab|DRUG: acetylsalicylic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: AMP-224|DRUG: AMP-224
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Study to Determine the Allergic Skin Activity After Different Skin Preparation
Status: COMPLETED
Conditions: Birch Pollen Allergy
Interventions: OTHER: prick lancet|OTHER: Tape stripping|OTHER: Microneedle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)
Status: TERMINATED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Placebo|DRUG: KBP-5074
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SYNCHRONOUS AND ASYNCHRONOUS TELEREHABILITATION METHODS IN PATIENTS WITH CERVICAL DISC HERNIATION
Status: COMPLETED
Conditions: Cervical Disc Herniation
Interventions: OTHER: Synchronous Exercise Program|OTHER: Asynchronous Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UMD rPA Regimen Trial in Adults
Status: TERMINATED
Conditions: Bacillus Anthracis (Anthrax)
Interventions: BIOLOGICAL: Anthrax vaccine absorbed made from Bacillus anthracis (AVA)|BIOLOGICAL: Recombinant protein antigen (rPA) made from Bacillus anthrax|BIOLOGICAL: Recombinant protein antigen (rPA) made from Escherichia coli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or Obese
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorders|Overweight or Obesity
Interventions: DRUG: NNC0165-1562|DRUG: Semaglutide|DRUG: Placebo (NNC0165-1562)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proximal Femoral Nail Antirotation™ (PFNA) Versus Gamma Nail 3™ (Gamma3) for Intramedullary Nailing of Unstable Trochanteric Fractures
Status: COMPLETED
Conditions: Unstable Trochanteric Fractures
Interventions: DEVICE: Proximal Femoral Nail AntirotationTM (PFNA)|DEVICE: Gamma Nail 3TM (Gamma3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copanlisib in Combination With Rituximab and CHOP Chemotherapy in Patients With Previously Untreated DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Copanlisib|DRUG: R-CHOP Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Exercise and Cognitive Training to Improve Everyday Function
Status: COMPLETED
Conditions: Effect of Exercise on Cognitive Function
Interventions: BEHAVIORAL: Intensive Exercise|BEHAVIORAL: Home Exercise|BEHAVIORAL: Cognitive Training|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Visceral vs Total Body Fat Reduction in Obese Female With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: BEHAVIORAL: low caloric diet, ultrasound cavitation,Kegel exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Infant Pain Responses Between Two Different Methods of Urine Collection
Status: UNKNOWN
Conditions: Pain|Intensive Care, Neonatal
Interventions: PROCEDURE: Percutaneous Suprapubic Aspiration|PROCEDURE: Urethral Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanisms Preventing Pharyngeal Reflux
Status: RECRUITING
Conditions: GERD
Interventions: DIAGNOSTIC_TEST: Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy|DIAGNOSTIC_TEST: Slow and rapid intra-esophageal infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Pembrolizumab With Standard Treatment in Patients With Recurrent Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 3D-printed on Lower Extremity Biomechanics in Individuals With Knee Osteoarthritis
Status: COMPLETED
Conditions: Medial Knee Osteoarthritis
Interventions: DEVICE: 3D-printed foot orthoses|DEVICE: 5 degrees lateral wedge insoles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Negative Pressure Ventilation in Patients Hospitalized With Acute Hypercapnic Respiratory Failure
Status: RECRUITING
Conditions: Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Intervention Arm (Biphasic cuirass ventilation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-stage Arthroplasty for the Septic Arthritis of the Native Knee Joint
Status: COMPLETED
Conditions: Septic Arthritis
Interventions: PROCEDURE: two-stage primary total knee arthroplasty with low-dose antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases.
Status: NOT_YET_RECRUITING
Conditions: Schistosoma Haematobium
Interventions: DIAGNOSTIC_TEST: Immunohistochemistry staining,|DIAGNOSTIC_TEST: microscopic examination of urine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of the Physiotherapy Program Applied in the Neonatal Intensive Care Unit
Status: COMPLETED
Conditions: Premature; Infant, Light-for-dates|Neonatal Disease|Neurodevelopmental Disorders|Motor Delay
Interventions: OTHER: Physiotherapy application|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Cryoablation|DRUG: PD-1 antibody and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of the Kidneys and Liver in the Elimination of Glucagon
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Liver Cirrhosis|Hyperglucagonemia
Interventions: BIOLOGICAL: Glucagon infusion|BIOLOGICAL: Primed tracer infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective, Non-randomized, Safety and Efficacy Study of a New Occluder Design for Minimally Invasive Closure of the Left Atrial Appendage (LAA) in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Implantation of LAA closure device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Venovenous Hemofiltration Versus Continuous Venovenuous Hemodialysis
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: PROCEDURE: Continuous Venovenous Hemofiltration (CVVH)|PROCEDURE: Continuous Venovenous Hemodialysis (CVVHD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Stable Angina|Coronary Artery Stenosis|Myocardial Infarction|Cardiovascular Diseases|Myocardial Ischemia|Atherosclerosis of Artery|Coronary Disease|Heart Diseases|Arterial Occlusive Diseases
Interventions: DEVICE: ScoreFlex balloon|DEVICE: Device: standard non-compliant balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Supplemental External Radiation With Pd-103 Versus Pd-103 Alone for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: External beam radiation|PROCEDURE: Pd-103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Text or Animation-based Narrative and Non-narrative Interventions to Enhance Cancer Literacy: a Pilot Study (CLARO)
Status: NOT_YET_RECRUITING
Conditions: Cancer Prevention
Interventions: OTHER: text in non-narrative form|OTHER: text in narrative form|OTHER: animated video in non-narrative form|OTHER: animated video in narrative form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Vitamin K2 for Reduction the Calcium at Carotid Bifurcation in Patients With Subcritical Lesions
Status: COMPLETED
Conditions: Carotid Plaques
Interventions: OTHER: Nutraceutical product based on vitamin K2 (PLAK2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: STRATEGIES to Improve Memory in Alzheimer's Disease
Status: WITHDRAWN
Conditions: Alzheimer Disease|Dementia, Mild|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Memory strategies in Arm 1|DEVICE: Electroencephalogram (EEG) headset in Arm 1|OTHER: Tablet in Arm 1|BEHAVIORAL: Memory strategies in Arm 2|DEVICE: Electroencephalogram (EEG) headset in Arm 2|OTHER: Tablet in Arm 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)
Status: COMPLETED
Conditions: COVID-19|Lung Injury, Acute|Kidney Injury
Interventions: DRUG: L-ascorbic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eslicarbazepine Acetate as Adjunctive Therapy for Refractory Partial Seizures
Status: COMPLETED
Conditions: Refractory Partial Epilepsy
Interventions: DRUG: eslicarbazepine acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Voice Treatment for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Dysphagia|Dysarthria
Interventions: BEHAVIORAL: Voice/Respiration Treatment|BEHAVIORAL: Speech/Articulation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low- or High-glycemic Index Diets on Metabolic and Inflammatory Responses in Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Low GI index diet|DIETARY_SUPPLEMENT: High GI diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Predictors and Moderators of Cognitive-Behavioral Therapy and Acceptance and Commitment Therapy for Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder|Cognitive-Behavioral Therapy|Acceptance and Commitment Therapy|Predictor
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy (CBT)|BEHAVIORAL: Acceptance and Commitment Therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 30 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Low dose Recombinant Herpes Zoster Vaccine (CHO cells)|BIOLOGICAL: High dose Recombinant Herpes Zoster Vaccine (CHO cells)|BIOLOGICAL: Positive control|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of the Effectiveness of Certain Physical Methods in the Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Biofeedback, Myomed 632|DEVICE: device for electrical stimulation, BTL 4000 Smart|OTHER: kinesitherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RP7214 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia and Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: RP7214
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 851B Gel for Treating High-Risk Cervical Human Papillomavirus Infection in Women.
Status: TERMINATED
Conditions: Papillomavirus Infections
Interventions: DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B|DRUG: 851B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Piloting Treatment With Intranasal Oxytocin in Phelan-McDermid Syndrome
Status: COMPLETED
Conditions: Phelan-McDermid Syndrome
Interventions: DRUG: Oxytocin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of TBCT Compared to ERP in the Treatment of OCD Patients, by the Assessment of Magnetic Resonance.
Status: COMPLETED
Conditions: OBSESSIVE COMPULSIVE DISORDER (OCD)
Interventions: BEHAVIORAL: Cognitive Therapy|BEHAVIORAL: Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Administration of COX 2 Inhibitors and Beta Blockers to Women Undergoing Breast Cancer Surgery
Status: UNKNOWN
Conditions: Primary Operable Breast Cancer
Interventions: DRUG: Propranolol, etodolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: HP518 - Dose Escalation|DRUG: HP518 - Dose Escalation|DRUG: HP518 -Dose Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand-assisted Laparoscopic Donor Nephrectomy Periumbilical Versus Pfannenstiel Incision
Status: UNKNOWN
Conditions: Donor Nephrectomy
Interventions: PROCEDURE: Periumbilical incision|PROCEDURE: Pfannenstiel incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Oxygen Saturation (SpO2) Noninvasive Pulse Oximeter Sensor (RD Disposable) Under Motion Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: RD Disposable Sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carbohydrate-induced Resilience of the Gut Microbiome After Antibiotics Use
Status: COMPLETED
Conditions: Overweight and Obesity|Insulin Resistance|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: Indigestible fiber (classified)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Pediatric Kidney Disease
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Breast Intervention During the Late Pregnancy on the Parturients' Breast Engorgement,Maternal Competence,and Stress
Status: RECRUITING
Conditions: Breastfeeding|Pregnancy Related|Efficacy, Self
Interventions: BEHAVIORAL: Breast pressure relief intervention at the end of pregnancy|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Valproate and Levocarnitine in Children With Spinal Muscular Atrophy
Status: UNKNOWN
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Valproate, Levocarnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)
Status: NOT_YET_RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: Problem Solving Treatment as usual (PST as usual)|BEHAVIORAL: Problem Solving Treatment Aid (PST-Aid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monocyte Antigen Carrier Cells for Newly Diagnosed GBM
Status: WITHDRAWN
Conditions: Glioblastoma|Glioma, Malignant
Interventions: BIOLOGICAL: MT-201-GBM monocyte vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy
Status: RECRUITING
Conditions: Epilepsy|Anomia|Temporal Lobe Epilepsy
Interventions: PROCEDURE: Speech therapy|PROCEDURE: Speech therapy assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modified Dosage for Severe Acute Malnutrition
Status: RECRUITING
Conditions: Severe Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: ready-to-use therapeutic food (RUTF)|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study the Efficacy of Bromocriptine in Patients With Hepatic/Cirrhosis Related Parkinsonism
Status: COMPLETED
Conditions: Cirrhosis Related Parkinsonism
Interventions: DRUG: Lactulose+Rifaximin +Bromocriptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Early Versus Delayed Etanercept in Patients With RA
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Methotrexate|DRUG: Sulfasalazine|DRUG: Hydroxychloroquine|DRUG: Etanercept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone-Primed Ovarian Simulation in Controlled-ovarian Simulation of Infertile PCOS Patients
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Injection of Cetrorelix|DRUG: Oral insertion of dydrogeserone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMART Trial to Predict Anhedonia Response to Antidepressant Treatment
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Sertraline|DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mulligan and Proprioceptive Neuromuscular Fasciliation Techiniques in Rotator Cuff Pathology
Status: COMPLETED
Conditions: Rotator Cuff Injuries
Interventions: OTHER: conservative rehabilitation|OTHER: mullgan mobilization techniques|OTHER: pnf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Expiratory Muscle Strength Training on Airway Protection and Swallowing in Chronic Dysphagia After Radiation Therapy
Status: UNKNOWN
Conditions: Cancer of the Head and Neck
Interventions: DEVICE: Expiratory Muscle Strength Training (EMST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sirolimus-Eluting Iron Bioresorbable Coronary Scaffold System (IBS)|DEVICE: Abbott Vascular XIENCE Everolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of Extended Release (ER) Naproxen Sodium
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Naproxen Sodium ER (BAYH6689)|DRUG: Naproxen Sodium IR (Aleve, BAYH6689)|DRUG: Naproxen Sodium ER Placebo|DRUG: Naproxen Sodium IR Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Trivalent Influenza Vaccine With Imiquimod
Status: COMPLETED
Conditions: Chronic Illness
Interventions: BIOLOGICAL: influenza vaccine|DRUG: Imiquimod|BIOLOGICAL: influenza vaccine|DRUG: Aqueous cream|BIOLOGICAL: influenza vaccine|DRUG: Aqueous cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Clinical Trial of MW33 Injection in Patients With COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: MW33 injection|COMBINATION_PRODUCT: MW33 injection placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IRAD2 : Patients With Respiratory Failure at Home
Status: COMPLETED
Conditions: Chronic Respiratory Failure|Nutritional Depletion
Interventions: BEHAVIORAL: education|DRUG: Oral dietary supplements (563 kcal/d), RESPIFOR|BEHAVIORAL: exercises on an ergometric bicycle 3 to 5 times a week|DRUG: 160 mg/d of oral testosterone undecanoate in men, 80 mg/d in women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Circadian Intervention Program for Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Pain|Sleep|Circadian Rhythm Disorders
Interventions: OTHER: Sleep and Circadian Intervention Program (SCIP) plus rehabilitation program|OTHER: Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BAT1308 Combined With Platinum-Based Chemotherapy± Bevacizumab For PDL1-Positive (CPS ≥1) Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Recombinant humanized anti-PD-1 monoclonal antibody injection|DRUG: Cisplatin|DRUG: Bevacizumab Injection|DRUG: carboplatin|DRUG: Paclitaxel for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer
Status: COMPLETED
Conditions: Precancerous Condition|Stage 0 Cervical Cancer
Interventions: OTHER: Cervical Papanicolaou Test|PROCEDURE: Conization|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Mesenchymal Stem Cells for the Treatment of Ileal Pouch Fistula's in Participants With Crohn's Disease
Status: UNKNOWN
Conditions: Ileal Pouch|Crohn Disease
Interventions: DRUG: Mesenchymal stem cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C|Cirrhosis|Hepatitis C Virus
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir and dasabuvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Vein Graft Properties Between Conventional & No-Touch Harvesting Technique - (PATENT SVG)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Coronary Artery Bypass Graft Surgery|PROCEDURE: Conventional open SVG harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dry Needling on Surface Electromyographic Activity in Latent Trigger Points
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: DEVICE: Intervention-Dry Needling|DEVICE: Control-Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Efficacy and Safety of Brimonidine Tartrate Preservative-Free Formulation in Adults With Ocular Redness"
Status: COMPLETED
Conditions: Ocular Redness
Interventions: DRUG: Brimonidine tartrate ophthalmic solution 0.025% preservative-free formulation|DRUG: Lumify® (brimonidine tartrate ophthalmic solution 0.025%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Apathy in Alzheimer's Dementia
Status: COMPLETED
Conditions: Apathy|Alzheimer's Dementia
Interventions: DEVICE: Neurostar repetitive transcranial magnetic stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IHD Versus CRRT for Severe Acute Kidney Injury in Critically Ill Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury
Interventions: PROCEDURE: continuous renal replacement therapy (CRRT)|PROCEDURE: Intermittent hemodialysis (IHD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VALUE- Vascular Access Laminate eUropean Experience. A Post Market Surveillance Study to Assess the Safety and Effectiveness of VasQ
Status: COMPLETED
Conditions: Arterio-Venous Fistula|Kidney Failure, Chronic|Kidney Diseases|Renal Failure Chronic|ESRD|Arteriovenous Fistula Thrombosis
Interventions: DEVICE: VasQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of OSI-906 in Combination With Pemetrexed in Advanced Solid Tumor Malignancies
Status: WITHDRAWN
Conditions: Cancer|Neoplasms|Tumors
Interventions: DRUG: OSI-906 and Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressive Muscle Relaxation According to Jacobson in Treatment of the Patients With Temporomandibular Joint Disorders
Status: COMPLETED
Conditions: TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME
Interventions: BEHAVIORAL: Muscle relaxation according to Jacobson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Immunoadsorption in Dilated Cardiomyopathy (IMPACT-DCM)
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DEVICE: protein A immunoadsorption|DEVICE: pseudo-immunoadsorption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Decisions in the Hospital Setting- M-Safety
Status: COMPLETED
Conditions: Diagnostic Errors
Interventions: BEHAVIORAL: Mindfulness breathing exercise|BEHAVIORAL: Diagnostic Checklist|BEHAVIORAL: Noise cancelling headphones|BEHAVIORAL: Privacy tablescreen|BEHAVIORAL: Diagnostic assistance application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Status: COMPLETED
Conditions: Chronic Pain|PTSD
Interventions: DEVICE: Home-based tDCS|BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Carcinoma|Gallbladder Carcinoma
Interventions: DRUG: Selumetinib|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT