pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Weight Gain, Maternal
Interventions: BEHAVIORAL: Goal-Oriented Episodic Future Thinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monoamine Contributions to Neurocircuitry in Eating Disorders
Status: COMPLETED
Conditions: Eating Disorder
Interventions: DRUG: [11C]raclopride|DRUG: [11C]DASB|DRUG: amphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics Centella Asiatica Product (CAP) in Mild Cognitive Impairment
Status: TERMINATED
Conditions: Cognitive Impairment|Elderly
Interventions: DRUG: 2g Centella asiatica water extract product|DRUG: 4g Centella asiatica water extract product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Immediate Effect of Electrical Stimulation Transcranial Direct Current (tDCS) Associated With the Use of FES, in Muscle Activity of the Tibialis Anterior Muscle, Balance and Plantar Pressure Distribution of Individuals With Hemiparesis Due to Stroke
Status: COMPLETED
Conditions: STROKE
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)|DEVICE: Functional electrical stimulation (FES)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perfusion-Induced Hyperthermia for Metastatic Carcinoma
Status: COMPLETED
Conditions: Metastatic Non-Small Cell Lung Carcinoma|Solid Tumor, Adult
Interventions: DEVICE: Exatherm-TBH system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: Malathion gel 0.5%|DRUG: Permethrin 1% rinse (Nix Crème)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIONICS 38 mm Trial EluNIR Ridaforolimus Eluting Coronary Stent System (EluNIR) In Coronary Stenosis Trial
Status: COMPLETED
Conditions: Coronary Stenosis
Interventions: COMBINATION_PRODUCT: EluNIR Ridaforolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intratumoral Injection of Autologous CD1c (BDCA-1)+ myDC, Avelumab, and Ipilimumab Plus Systemic Nivolumab
Status: COMPLETED
Conditions: Solid Tumor|Metastases to Soft Tissue
Interventions: DRUG: intratumoral injection of autologous CD1c (BDCA-1)+ myDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chompions! A Treatment Study for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
Status: ACTIVE_NOT_RECRUITING
Conditions: ARFID|Picky Eating|Eating Disorders in Children
Interventions: BEHAVIORAL: Family Assisted Diet (FAD)|BEHAVIORAL: Feeling and Body Investigator_ARFID Division (FBI-ARFID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Low-Dose Radiation Therapy in Treating Patients With Stage I or Stage IIA Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Hodgkin Disease|Lymphoma|Hodgkin Disease|Lymphoma: Hodgkin
Interventions: DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Bleomycin|DRUG: Etoposide|RADIATION: Low-dose radiotherapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection
Status: TERMINATED
Conditions: Lung Cancer|Breast Cancer|Ovarian Cancer
Interventions: OTHER: exhalation analysis of breath sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy
Status: RECRUITING
Conditions: Adverse Effect of Cardiovascular Medications (Diagnosis)
Interventions: DRUG: Evolocumab combined with statins|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intubating Conditions of Neuromuscular Blockade
Status: ENROLLING_BY_INVITATION
Conditions: Endotracheal Intubation
Interventions: PROCEDURE: Endotracheal Intubation at TOFC=1|PROCEDURE: Endotracheal Intubation 2 minutes after rocuronium administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Performance of the CogState Computerized Neuropsychological Battery in Patients With Alzheimer's Disease (0000-086)(COMPLETED)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Comparator: Placebo 5mg (run in)|DRUG: Donepezil 5 - 10 mg|DRUG: Comparator: Placebo 5-10 mg|DRUG: Donepezil 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Transcendence Facilitation Psychoeducational Program Applied to Mothers of Children With Special Needs
Status: NOT_YET_RECRUITING
Conditions: Mothers|Special Needs Children|Psychoeducation|Well-being
Interventions: BEHAVIORAL: The ST-Facilitation Psychoeducation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Crizotinib in Patients With c-MET Positive Gastric Adenocarcinoma as a Third-line Chemotherapy
Status: COMPLETED
Conditions: c-MET Positive Gastric Cancer
Interventions: DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Olaparib, and Temozolomide for People With Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: DRUG: Pembrolizumab|COMBINATION_PRODUCT: Olaparib and Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Session of tDCS (Transcranial Direct Current Stimulation) Improves Endurance for 30 Minutes
Status: COMPLETED
Conditions: Athlete|Healthy
Interventions: DEVICE: TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Novel Social Media Intervention For Older Br CA Patients
Status: COMPLETED
Conditions: Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: OTHER: PatientsLikeMe (PLM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PI3Kδ Inhibitor Parsaclisib Combined With Chidamide for the Treatment of Relapsed/Refractory Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: Parsaclisib|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver
Status: COMPLETED
Conditions: Metastases, Neoplasm|Colorectal Neoplasms|Esophageal Neoplasms|Stomach Neoplasms|Pancreatic Neoplasms|Breast Neoplasms|Melanoma|Sarcoma|Gastrointestinal Neoplasms|Lung Neoplasms|Liver Neoplasms|Cholangiocarcinoma
Interventions: DRUG: MTC-DOX for Injection|PROCEDURE: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Possible Health Effects of Lean Fish, Fatty Fish and Lean Meat Intake in Non-obese Adults
Status: COMPLETED
Conditions: Metabolic Disorders|Obesity
Interventions: OTHER: Lean fish|OTHER: Fatty fish|OTHER: Lean meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Three Dimensional Printed Versus Conventional Heat Cured Acrylic Complete Denture
Status: COMPLETED
Conditions: Completely Edentulous Patients
Interventions: DEVICE: two different denture manufacturing technique (heat cure pack and press technique(heat cure acrylic,Acrostone,Egypt)/3d printed dneture(HARZ lab,Russia))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remifentanil Without Muscle Relaxant for Thoracotomy
Status: COMPLETED
Conditions: Elective Open Thoracotomy
Interventions: DRUG: Muscle Relaxants (MR) group|DRUG: Non- Muscle Relaxants (NMR) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Synchronous Radiofrequency /Microwave Ablation to Treat Large and Huge Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Thermal Ablation|DRUG: EADM|DRUG: Ultra-fluid lipiodol|OTHER: Gelatin sponge articles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Response Rate to the Licensed Pneumovax 23™ in Elderly Population.
Status: COMPLETED
Conditions: Streptococcus Pneumoniae Vaccines
Interventions: BIOLOGICAL: Pneumovax 23™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Oral Probiotic and Antibiotic Administration in Patients With Chronic Periodontitis
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus SP1|DRUG: Azithromycin|OTHER: Talc powder|PROCEDURE: Periodontal treatment Scaling and root planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manual Treatment for Hemiplegic Shoulder Pain and Upper Extremity Function in Stroke Patients
Status: RECRUITING
Conditions: Hemiplegic Shoulder Pain|Osteopathic Manipulative Treatment
Interventions: OTHER: Osteopathic Manual Treatment|OTHER: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Acetaminophen (ACE) in Post-operative Dental Pain
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Acetaminophen (ACE) (1000 mg)|DRUG: Commercial ACE (1000 mg)|DRUG: Commercial Ibuprofen (IBU) (400 mg)|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled TPI-1020 Versus Inhaled Budesonide in Smokers With Mild Reversible Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: TPI-1020|DRUG: budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Omega-3 Food Supplement in Healthy Subjects
Status: COMPLETED
Conditions: Biological Availability
Interventions: DIETARY_SUPPLEMENT: Pronova Pure 150:500 EE EU|DIETARY_SUPPLEMENT: Pronovum PRF-037|DIETARY_SUPPLEMENT: Pronovum PRF-041|DIETARY_SUPPLEMENT: Eskimo-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy
Status: COMPLETED
Conditions: Hyperlipidemias
Interventions: COMBINATION_PRODUCT: Bempedoic Acid + Ezetimibe Fixed-Dose Combination|DRUG: Bempedoic Acid|DRUG: Ezetimibe|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression
Status: RECRUITING
Conditions: Metastatic Breast Cancer|ER+ Breast Cancer|Advanced Breast Cancer
Interventions: DRUG: Ipatasertib 300mg|DRUG: Fulvestrant 500g|DRUG: Palbociclib 75mg-125mg|DRUG: CDK4/6 Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study on the Effect of NovoMix® 30, Levemir® or NovoRapid® (Alone or Combined) in Type 2 Diabetics Previously Treated With Anti-diabetic Medication
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin aspart|DRUG: insulin detemir|DRUG: biphasic insulin aspart
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-Dense Docetaxel Before or After Doxorubicin/Cyclophosphamide in Axillary Node-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide (AC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronan in the Treatment of Painful Achilles Tendinopathy.
Status: COMPLETED
Conditions: Tendinopathy
Interventions: DEVICE: hyaluronic acid sodium salt|DEVICE: ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
Status: NOT_YET_RECRUITING
Conditions: Fabry Disease
Interventions: DRUG: PRX-102 1 mg/kg every two weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: senofilcon A|DEVICE: lotrafilcon B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Pain Study Comparing Different Treatments After Hand Surgery
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: 5mg of Oxycodone every 6 hours as needed for pain|DRUG: 600mg of Ibuprofen every 6 hours as needed for pain|DRUG: 500mg of Acetaminophen every 6 hours as needed for pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome
Status: RECRUITING
Conditions: Post-acute COVID-19 Syndrome|Postural Tachycardia Syndrome (POTS)|Long COVID|SARS CoV 2 Infection
Interventions: DIAGNOSTIC_TEST: Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls|DIAGNOSTIC_TEST: Levels of inflammatory cytokine ( IL-6) in controls|DIAGNOSTIC_TEST: Effect on inflammation after chronic PNS stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiotherapy Plus Concurrent Nimotuzumab or Cisplatin in Stage II-III Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Nasopharyngeal Neoplasms|Nasopharyngeal Diseases|Head and Neck Neoplasm
Interventions: DRUG: Nimotuzumab|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: Rilvegostomig|BIOLOGICAL: Volrustomig|BIOLOGICAL: Sabestomig|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Study of Modified Transoesophageal Echocardiography on Cerebral Embolization After Cardiothoracic Surgery
Status: COMPLETED
Conditions: Coronary Artery Atherosclerosis
Interventions: OTHER: A-View
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hospital-Induced Immobility
Status: COMPLETED
Conditions: In-hospital Mobility|Geriatric|Immobilization
Interventions: BEHAVIORAL: A Mobilisation Initiative|BEHAVIORAL: Focus Group Interviews|BEHAVIORAL: Formal Education|BEHAVIORAL: Self-reported Level of Mobilisation|BEHAVIORAL: Observations of Patients and the Environment|BEHAVIORAL: Awareness of Mobilisation Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of CCX168 in Japanese and Caucasian Healthy Adult Males
Status: COMPLETED
Conditions: Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Interventions: DRUG: CCX168|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Gantenerumab in Participants With Mild Alzheimer Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo|DRUG: Gantenerumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SHR-1316 in Combination With Chemotherapy in Patients With Esophageal Squamous Cell Cancer
Status: UNKNOWN
Conditions: Advanced Esophageal Squamous Cell Cancer
Interventions: DRUG: Irinotecan liposome|DRUG: SHR-1316|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Orforglipron|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Feasibility of a Dynamic Exercise Intervention. Psychosocial Effects and Process Evaluation of the Experimental Design.
Status: UNKNOWN
Conditions: Stability|Old Age; Debility|Balance; Distorted
Interventions: OTHER: Evaluation of the feasibility, psychosocial effects, influence and perception of exercise selection an experimental design of exercises performed at the hip and chest region.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Timing of FFR-guided PCI for Non-IRA in NSTEMI and MVD (OPTION-NSTEMI)
Status: RECRUITING
Conditions: Myocardial Infarction, Acute|Multi-Vessel Coronary Artery Stenosis|Multi Vessel Coronary Artery Disease
Interventions: PROCEDURE: Staged in-hospital complete revascularization|PROCEDURE: Immediate complete revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|AML1-ETO Fusion Protein Expression
Interventions: DRUG: Fludarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Weekly Paclitaxel for Patients With Recurrent Endometrial or Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Recurrent Ovarian Cancer|Primary Peritoneal Carcinoma|Recurrent Endometrial Cancer
Interventions: DRUG: Lenvatinib Mesylate|DRUG: Paclitaxel|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Tumors|Solid Tumors|Metastatic Cancer
Interventions: BIOLOGICAL: EGFRBi-armed autologous activated T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial on Platelet Rich Plasma Versus Saline Dressing of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: PRP gel|DRUG: Saline dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Labour Pain is a Subjective Experience. The Degree of a Woman's Suffering in Childbirth Depends on Indirect Factors
Status: COMPLETED
Conditions: Pain, Labor
Interventions: DIAGNOSTIC_TEST: Visual analogue scale (VAS)|DIAGNOSTIC_TEST: General anxiety scale (GAD-2) and survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kinematics of Lower Limb, Pain and Function of the Women With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Strength|OTHER: Sensorimotor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEDI-524 (Motavizumab) for the Prevention of Respiratory Sycytial Virus (RSV) Disease Among Native American Indian Infants in the Southwestern United States
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Motavizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitation
Status: COMPLETED
Conditions: Aortic Regurgitation|Functional Mitral Regurgitation
Interventions: PROCEDURE: Aortic valve replacement|PROCEDURE: Mitral valve annuloplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining Restrictive Guidelines and a NIRS SCORE to Decrease RBC Transfusions
Status: COMPLETED
Conditions: Anemia of Prematurity (AOP)
Interventions: OTHER: Restrictive transfusions based on SCOR assessment|OTHER: Liberal transfusions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Laparoscopic Approach to Cancer of the Endometrium
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Total Abdominal Hysterectomy|PROCEDURE: Total Laparoscopic Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon
Status: COMPLETED
Conditions: Inflammation|Death, Sudden, Cardiac|Death|Heart Diseases|Cardiovascular Diseases|Pathologic Processes|Death, Sudden|Blood Coagulation Disorders|Respiratory Tract Infections
Interventions: DRUG: Wobenzym plus|DRUG: PL 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics, Pharmacodynamics, and Safety of Glyburide in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glyburide|DRUG: Canagliflozin (JNJ-28431754)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine and Rituximab With or Without Orelabrutinib in MCL Treatment
Status: RECRUITING
Conditions: Mantle Cell Lymphoma (MCL)
Interventions: DRUG: Orelabrutinib|DRUG: Bendamustine|DRUG: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose, Phase 1 Study of YH35324 in Patients With Various Allergic Diseases
Status: RECRUITING
Conditions: Allergic Disease|Chronic Spontaneous Urticaria|Chronic Inducible Urticaria|Cold Urticaria
Interventions: DRUG: YH35324|DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Neuromuscular Taping Technique on Upper Limbs Edema in Cardiac Surgery Patients
Status: RECRUITING
Conditions: Edema Limbs
Interventions: DEVICE: neuromuscolar tape|BEHAVIORAL: antigravity arm position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT
Status: COMPLETED
Conditions: Minimal Residual Disease|Donor Lymphocyte Infusion|Hematopoietic Stem Cell Transplantation|Relapse
Interventions: BIOLOGICAL: donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis (VRH) in a Clinical Population
Status: UNKNOWN
Conditions: Cancer
Interventions: DEVICE: Clinical - Hypnosis with VR (VRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPO
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence, Urge|Urgency-frequency Syndrome|Post Prostatectomy
Interventions: PROCEDURE: Li-SWT (suprapubic approach)|PROCEDURE: Li-SWT (perineal approach)|PROCEDURE: Li-SWT (combined approach)|PROCEDURE: Sham treatment|DRUG: Solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US
Status: COMPLETED
Conditions: Healthy Volunteers (Meningococcal Infection)
Interventions: BIOLOGICAL: MenACYW conjugate vaccine|BIOLOGICAL: MenACYW-135 conjugate vaccine|BIOLOGICAL: DTaP-IPV//Hib vaccine|BIOLOGICAL: Pneumococcal 13-valent conjugate vaccine|BIOLOGICAL: Pentavalent rotavirus vaccine|BIOLOGICAL: Hepatitis B vaccine|BIOLOGICAL: Measles, mumps, rubella (MMR) vaccine|BIOLOGICAL: Varicella vaccine|BIOLOGICAL: Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Flat Foot and Coronal Spinopelvic Alignment
Status: UNKNOWN
Conditions: Flat Foot [Pes Planus] (Acquired), Left Foot|Flat Foot [Pes Planus] (Acquired), Right Foot|Flat Foot Acquired Bilateral (Pes Planus)|Pelvic Obliquity|Spinal Curvatures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect and Safety of a Novel CGM-Based Titration Algorithm for Basal Insulin in T2DM Participants.
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DEVICE: Continuous Glucose Monitoring (CGM)-based titration algorithm implemented in DiAs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: OC-01 (varenicline 0.6mg/ml) Nasal Spray|DRUG: Placebo (vehicle) nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragmatic Motion Using Linear Ultrasound
Status: COMPLETED
Conditions: Diaphragm; Movement|Examination of Diaphragm Movement Using Ultrasound
Interventions: DIAGNOSTIC_TEST: Linear Ultrasound to Measure Diaphragmatic Movement|DIAGNOSTIC_TEST: Curvilinear Ultrasound to Measure Diaphragmatic Movement|DIAGNOSTIC_TEST: Pulmonary function tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma|Back Pain|Benign Prostatic Hypertrophy|Bursitis|Depression|Anxiety|Diabetes Mellitus|Esophageal Reflux|HIV Infections|Hyperlipidemia|Hypertension|Insomnia|Irritable Bowel Syndrome|Obesity|Osteoporosis (Senile)|Shoulder Pain|Sinusitis|Symptomatic Menopause|Urinary Incontinence|Urinary Tract Infection|Vaginitis
Interventions: OTHER: Health Information Prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Boston Scientific Embolic Protection, Inc. (EPI): A Carotid Stenting Trial for High-Risk Surgical Patients (BEACH)
Status: COMPLETED
Conditions: Carotid Artery Diseases|Stroke|Cerebral Arteriosclerosis
Interventions: DEVICE: WALLSTENT® Endoprosthesis™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Flucytosine|DRUG: Fluconazole|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Characterization of priMary And sEcondary STress Related takOtsubo
Status: RECRUITING
Conditions: Takotsubo Cardiomyopathy|Sepsis-induced Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Positron Emission Tomography (PET) analysis|DIAGNOSTIC_TEST: Blood samples collection|OTHER: Clinical follow up visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Feasibility Study of the Cordis Neurovascular Self Expanding Stent System in Intracranial Arteries
Status: COMPLETED
Conditions: Atherosclerosis|Aneurysm
Interventions: DEVICE: Cordis Neurovascular ENTERPRISE Self Expanding Stent System|DEVICE: Cordis Neurovascular ENTERPRISE Self Expanding Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition
Status: RECRUITING
Conditions: Ultrasound Finding: Ovulation Inhibition, Ovarian Activities|Cervical Mucus|Serum Hormonal Profile
Interventions: DRUG: Quadriphasic Estradiol valerate 1 - 3 mg/ Dienogest 2 - 3 mg (26/2)|DRUG: Ethinylestradiol (EE) 20 mcg/Gestodene 75 mcg (21/7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 5-FU, Oxaliplatin, & Lapatinib Combined With Radiation Therapy to Treat HER2 Positive Esophagogastric Cancer
Status: TERMINATED
Conditions: HER2 Positive Esophagogastric Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Oxaliplatin|DRUG: Lapatinib|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Stage IV Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: dasatinib|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of Co-administration of DWC202206 and DWC202207 in Patients With Concomitant Hypertension and Hyperlipidemia
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Hyperlipidemias
Interventions: DRUG: (D) DWC202206|DRUG: (D) DWC202207|DRUG: (P) DWC202206|DRUG: (P) DWC202207
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 and Oxyntomodulin Release in Relation to Diet in Type 2 Diabetes Patients.
Status: COMPLETED
Conditions: Type-2 Diabetes
Interventions: DIETARY_SUPPLEMENT: High-fiber vegetarian meal|DIETARY_SUPPLEMENT: Mediterranean-like meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biopsy Technique for Endoscopic Surveillance of Hereditary Diffuse Gastric Cancer
Status: COMPLETED
Conditions: Hereditary Diffuse Gastric Cancer
Interventions: OTHER: Single bite biopsy technique|OTHER: Double bite biopsy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate KOS-1584 in Patients With Advanced or Metastatic Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: KOS-1584
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi and PE5i
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Ramipril|DRUG: Tadalafil|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Focused Shock Wave in the Release od Delayed Onset Muscle Soreness (DOMS)
Status: COMPLETED
Conditions: Musculoskeletal Pain|Athletic Injuries
Interventions: DEVICE: Verum focused extracorporeal shockwave|DEVICE: Sham shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of Single Ascending Oral Doses of INX-08189 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: INX-08189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Studying Blood and Tumor Tissue Samples in Women With Invasive Breast Cancer, Ductal or Lobular Carcinoma in Situ, or Benign Breast Disease
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: proteomic profiling|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: fluorescent antibody technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: medical chart review|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous Keratopathy
Status: COMPLETED
Conditions: Bullous Keratopathy
Interventions: PROCEDURE: amniotic membrane transplantation|PROCEDURE: anterior stromal puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehospital Intubation of COVID-19 Patient With Personal Protective Equipment
Status: COMPLETED
Conditions: Intubation Complication|Intubation; Difficult or Failed|Cardiac Arrest|Influenza|Safety Issues
Interventions: PROCEDURE: Direct laryngoscopy|PROCEDURE: Vie Scope laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG PET/CT Imaging for Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female|Breast Cancer Recurrent
Interventions: OTHER: 18F-FDG PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Probiotics for the Prevention of Antibiotics Associated Diarrhoea and Clostridium Difficile Associated Diarrhoea
Status: COMPLETED
Conditions: Diarrhoea
Interventions: DRUG: VSL#3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers
Status: TERMINATED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Exenatide|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib in Patients With Waldenström's Macroglobulinemia, Chronic Lymphocytic Leukemia, Marginal Zone Lymphoma and Follicular Lymphoma
Status: RECRUITING
Conditions: Waldenström's Macroglobulinemia|Chronic Lymphocytic Leukemia|Marginal Zone Lymphoma|Follicular Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Obinutuzumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacogenomics of Antiplatelet Response - I
Status: COMPLETED
Conditions: Platelet Aggregation|Platelet Transcriptome|Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Gum Arabic Supplementation in Hemodialysis Patients
Status: UNKNOWN
Conditions: Kidney Failure, Chronic
Interventions: DIETARY_SUPPLEMENT: Gum Arabic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: MAD Study to Assess the Safety, Tolerability, PKs and Efficacy of YJ001 for Spray Use in Patients With DPNP
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: YJ001 for Spray Use|DRUG: Placebo of YJ001 for Spray Use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: LY2157299
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Treatment for Concussion in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Concussion, Mild
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic Acid
Status: COMPLETED
Conditions: Primary Biliary Cholangitis (PBC)
Interventions: DRUG: Elafibranor 80 mg|DRUG: Elafibranor 120 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee Pain
Interventions: DRUG: SL-1002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: DEVICE: Laser treatment|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.
Status: COMPLETED
Conditions: Cancer|Advanced Solid Tumors
Interventions: DRUG: Sunitinib|DRUG: Sorafenib|DRUG: Erlotinib|DRUG: Everolimus|DRUG: Lapatinib|DRUG: Dasatinib|DRUG: Pazopanib|DRUG: Vemurafenib|PROCEDURE: tumor biopsy|PROCEDURE: skin biopsy (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload
Status: COMPLETED
Conditions: Hemoglobinopathies|Myelodysplastic Syndromes|Other Inherited or Acquired Anaemia|MPD Syndrome|Diamond-Blackfan Anemia|Other Rare Anaemias|Transfusional Iron Overload
Interventions: DRUG: deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Pemetrexed for Leptomeningeal Metastasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Leptomeningeal Metastases
Interventions: DRUG: Pemetrexed (1)|DRUG: Pemetrexed (2)|DRUG: Folic Acid|DRUG: Vitamin B12|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Nintedanib (BIBF 1120)|DRUG: Placebo|DRUG: BSC|DRUG: BSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Sugar-Free Chewing Gum Containing Magnolia Bark Extract on Caries Lesions in Healthy Adult Volunteers
Status: UNKNOWN
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Chewing gum administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Subcutaneous Insulin Infusion strAtegy Versus Multiple Daily Insulin Injections strAtegy
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Transient Continuous Subcutaneous Insulin Infusion|DRUG: Transient Multiple Daily Insulin Injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of iCo-007 Intravitreal Injection to Treat Diabetic Macular Edema
Status: COMPLETED
Conditions: Diffuse Diabetic Macular Edema
Interventions: DRUG: iCo-007 Intravitreal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Therapy Under Ultrasound Guided Manual Vacuum Aspiration
Status: RECRUITING
Conditions: First Trimester Abortion|Surgical Abortion|Music Intervention|Local Anesthesia|Pain
Interventions: BEHAVIORAL: music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT