pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combined Neoadjuvant Systemic and PIPAC Therapy (NASPIT) for Patients With Colorectal Peritoneal Metastasis Eligible for CRS and HIPEC: A Prospective Phase II Trial
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer|Peritoneal Carcinomatosis|Colon Adenocarcinoma
Interventions: PROCEDURE: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of FSR Peptide Versus Placebo Following Punch Biopsy
Status: COMPLETED
Conditions: Wound Heal
Interventions: DRUG: FSR Peptide 20μM|DRUG: FSR Peptide 50μM|DRUG: FSR Peptide 100μM|DRUG: FSR Peptide 200μM|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of JNJ-53718678 on the Cardiac Repolarization Interval in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-53718678, 2000 mg|DRUG: JNJ-53718678, 3000 mg|DRUG: JNJ-53718678, 4500 mg or Dose to be decided|DRUG: JNJ-53718678 500 mg|DRUG: JNJ-53718678 Placebo|DRUG: Moxifloxacin 400 mg|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sequencing of Stereotactic Ablative Body Radiotherapy in Combination With PD-1 Blockade Using Pembrolizumab in Metastatic Non-Small Cell Lung Carcinoma
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Short-term Impact of Vocal Intonation Therapy (VIT) and Therapeutic Singing (TS) on Respiratory Function in Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Vocal Intonation Therapy (VIT)|BEHAVIORAL: Therapeutic Singing (TS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindfulness Training for Psychotherapeutic Care
Status: COMPLETED
Conditions: Mindfulness, Compassion|Empathy, Working Alliance, Patients' Symptomatology, Psychotherapeutic Process|Psychotherapist
Interventions: BEHAVIORAL: MCBI|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: odanacatib|DRUG: Comparator: placebo to MK0822
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HALT Progression of Polycystic Kidney Disease Study B
Status: COMPLETED
Conditions: Kidney, Polycystic
Interventions: DRUG: Lisinopril|DRUG: Telmisartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
Status: COMPLETED
Conditions: Stroke|Spasticity as Sequela of Stroke|Upper Limb Hypertonia
Interventions: OTHER: Lycra sleeve|OTHER: Rehabilitation|DRUG: Botulinum Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy With TP+5-FU or TP+Cetuximab Followed by Radioimmuptherapy for Locally Advanced or Not Resectable SCCHNN
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Hypopharynx Stage III|Squamous Cell Carcinoma of the Hypopharynx Stage IV|Squamous Cell Carcinoma of the Larynx Stage III|Squamous Cell Carcinoma of the Larynx Stage IV|Squamous Cell Carcinoma of the Oropharynx Stage III|Squamous Cell Carcinoma of the Oropharynx Stage IV|Squamous Cell Carcinoma of the Oral Cavity Stage III|Squamous Cell Carcinoma of the Oral Cavity Stage IV
Interventions: DRUG: Docetaxel|DRUG: Cisplatin|DRUG: 5-fluorouracil|BIOLOGICAL: Cetuximab Induction|BIOLOGICAL: Cetuximab Radioimmunotherapy|RADIATION: Boost irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tisagenlecleucel in Combination With Pembrolizumab in r/r Diffuse Large B-cell Lymphoma Patients
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubes
Status: COMPLETED
Conditions: Otitis Media
Interventions: DRUG: OTO-201 (ciprofloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Intraarticular betamethasone|DRUG: Cyclosporine/placebo-cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reducing Respiratory Virus Transmission in Bangladeshi Classrooms
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV2 Infection|Influenza Viral Infections|Respiratory Viral Infection
Interventions: DEVICE: Box Fan|DEVICE: UV Germicidal Irradiation Lamp Unit|DEVICE: Combined: Box Fan and UV Germicidal Irradiation Lamp Units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Lymphoma|Neutropenia|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cyclosporine|DRUG: irinotecan hydrochloride|DRUG: phenobarbital
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Degradation of the Anorexic Hormone Peptide YY
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PYY1-36 infusion|BIOLOGICAL: PYY1-36 + sitagliptin|BIOLOGICAL: PYY3-36 infusion|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Atrial Tachycardia as a Predictor of Atrial Fibrillation, Stroke and Mortality in Cryptogenic Stroke
Status: UNKNOWN
Conditions: Cryptogenic Stroke|Atrial Fibrillation|Atrial Tachycardia
Interventions: OTHER: follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ZN-c3 + Gemcitabine in Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Adenocarcinoma|Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Zentalis|DRUG: Gemzar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative, Controlled Study to Evaluate the Clinical Accuracy of the Velieve U.S. UTI Urine Analysis Test System
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DEVICE: Velieve U.S.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Induction Cisplatin and Capecitabine Followed by Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: cisplatin, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer's Disease|Amnestic Mild Cognitive Impairment
Interventions: DRUG: AH110690 (18F) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications
Status: COMPLETED
Conditions: Cesarean Section; Complications, Wound, Dehiscence
Interventions: DEVICE: Silver-impregnated antimicrobial dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FOLFOXIRI Plus Cetuximab vs. FOLFOXIRI Plus Bevacizumab 1st-line in BRAF-mutated mCRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Folinic acid|DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Increasing DR Screening Through TOP: Supporting Implementation and Identifying Opportunities for Scale up in Ontario
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1
Interventions: OTHER: a mail letter, a phone call and a phone call plus mailed letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Participants With MCI or Mild AD
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: ACU193|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between Two Albendazole 400 mg Tablets in Healthy Adult Participants Under Fed Conditions
Status: COMPLETED
Conditions: Intestinal Diseases
Interventions: DRUG: Albendazole IP 400 mg|DRUG: Albendazole 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase 2/3 Open-Label Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy
Status: ENROLLING_BY_INVITATION
Conditions: Immunoglobulin A Nephropathy
Interventions: DRUG: Sibeprenlimab 400 mg s.c. Q4weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: morphine sulfate sustained-release capsules|DRUG: KADIAN (morphine sulfate sustained-release) capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation
Status: COMPLETED
Conditions: Islet Transplantation in Diabetes Mellitus Type 1
Interventions: DRUG: Reparixin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Hereditary Breast/Ovarian Cancer - BRCA1|Hereditary Breast/Ovarian Cancer - BRCA2|Male Breast Cancer|Progesterone Receptor-negative Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Triple-negative Breast Cancer
Interventions: DRUG: veliparib|DRUG: cisplatin|DRUG: vinorelbine tartrate|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ro 50-3821 in Treating Anemia in Patients Receiving Antineoplastic Therapy for Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Anemia|Lung Cancer
Interventions: BIOLOGICAL: methoxy polyethylene glycol epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: lintuzumab|DRUG: arsenic trioxide|DRUG: idarubicin|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Citicoline in Individuals With Mild Traumatic Brain Injury (mTBI)
Status: WITHDRAWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: Citicoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medication Integration in Treatment of Comorbid Adolescent Substance Users/Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Attention Deficit Disorder
Interventions: BEHAVIORAL: MIP Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Randomized, Double-Blind, Dose Escalation Study in Postoperative Pain Open Inguinal Herniorrhaphy
Status: COMPLETED
Conditions: Inguinal Herniorrhaphy
Interventions: DRUG: CPL-01|DRUG: Naropin 150 MG Per 20 ML Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preload Dependency Evaluation With Stroke Volume Variation During Alveolar Recruitment Manoeuvres
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Bypass|Hypovolemia|Anesthesia, General|Pulmonary Atelectasis
Interventions: OTHER: tee measurement|OTHER: flotrac measurement|OTHER: clearsight measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open-Label Pilot Study to Evaluate Switching From a Regimen Consisting of Raltegravir Plus Emtricitabine/Tenofovir DF Fixed-Dose Combination to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected Patients
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: Stribild
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD
Status: RECRUITING
Conditions: Opioid-Use Disorder
Interventions: OTHER: Placebo|DRUG: TRV734
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Resting Metabolic Rate Following Orthopedic Surgery
Status: RECRUITING
Conditions: Metabolism; Disorder, Postprocedural|Resting Metabolic Rate|Post Operative Nutrition
Interventions: OTHER: Pre-surgical nutrition, hydration, RMR, and body composition assessments|OTHER: Post-surgical nutrition, hydration, RMR and body composition assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC
Status: COMPLETED
Conditions: Colorectal Cancer|Metastasis
Interventions: DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker-based Study in R/M SCCHN
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Afatinib|DRUG: Palbociclib|DRUG: standard of care|DRUG: IPH2201|DRUG: Durvalumab|DRUG: Niraparib|DRUG: INCAGN01876
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MAX Study: Mitomycin C, Avastin and Xeloda in Patients With Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Mitomycin C; Capecitabine; Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Antibiotic Cement (ABC) Compared to Regular Cement in Reducing the Rate of Infection Following Total Knee Arthroplasty: The ABC Trial
Status: WITHDRAWN
Conditions: Infection|Osteoarthritis of the Knee
Interventions: DEVICE: Simplex™ P with Tobramycin|DEVICE: Simplex™ P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies
Status: TERMINATED
Conditions: Centronuclear Myopathy
Interventions: DRUG: DYN101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple-dose Study of the Safety and Tolerability of REGN88(SAR153191) in Rheumatoid Arthritis Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: REGN88
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: DIETARY_SUPPLEMENT: Nutritional perioperative prehabilitation program for two weeks|DIETARY_SUPPLEMENT: Nutritional perioperative prehabilitation program for one week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function
Status: COMPLETED
Conditions: Stimulant Use|MDMA ('Ecstasy')|Social Behavior|Motivation
Interventions: DRUG: MDMA|DRUG: Methamphetamine|DRUG: placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rituximab Objective Outcome Measures Trial in SLE
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus Arthritis
Interventions: DRUG: Rituximab|DRUG: Methylprednisolone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reoperation Rate in Breast-Conserving Surgery Using Confocal Histolog® Scanner for Intraoperative Margin Assessment
Status: COMPLETED
Conditions: Breast Cancer - Ductal Carcinoma in Situ (DCIS)|Breast-Conserving Surgery
Interventions: DEVICE: Histolog Scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)
Status: RECRUITING
Conditions: Endometrial Cancer|Esophageal Cancer|Esophagogastric Junction (EGJ)|Gastric (Stomach) Cancer|Head and Neck Cancer|Melanoma|Ovarian Cancer|Non-small Cell Lung (NSCLC)|Urothelial Cancer
Interventions: GENETIC: Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Program for Adults With Type 2 Diabetes Mellitus (DiMe-SALUD2 Project)
Status: RECRUITING
Conditions: Tobacco Use Disorder|Diabetes Mellitus, Type 2
Interventions: OTHER: Control group (waiting list)|BEHAVIORAL: Cognitive Behavioral Treatment (CBT) for smoking cessation|BEHAVIORAL: CBT for smoking cessation + DiMeSALUD2 protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Roflumilast to Prevent Exacerbations in Fibrotic Sarcoidosis Patients (REFS)
Status: UNKNOWN
Conditions: Sarcoidosis
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-Cell Depleted Double UCB for Refractory AML
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Refractory Acute Myelogenous Leukemia
Interventions: DRUG: Allopurinol|DRUG: Fludarabine|RADIATION: Total body irradiation|DRUG: Cyclophosphamide|DRUG: Levetiracetam|DRUG: Busulfan|BIOLOGICAL: Umbilical Cord Blood Transplantation|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REducing SEDENTary Behaviour May Slow Cognitive Decline in Older Adults With Mild Cognitive Impairment: A Pilot Study
Status: COMPLETED
Conditions: Cognitive Impairment|Physical Functioning|Quality of Life
Interventions: BEHAVIORAL: Reducing Sedentary Behaviour Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.
Status: COMPLETED
Conditions: Irreversible Pulpitis|Apical Periodontitis|Root Canal Infection
Interventions: DRUG: ethanolic extract of sapindus mukorossi|DRUG: ethylene diamine tetra acetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Two Techniques for Pain Control After Bariatric Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Bariatric Surgery Candidate
Interventions: PROCEDURE: Transversus Abdominis Plane (TAP) block|PROCEDURE: Port-Site Infiltration (PSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Probe for Management of Unresectable Bile Duct and Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DEVICE: Endoscopic Bipolar RadioFrequency Probe used to remove tumors in bile duct to manage Pancreatic Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health-Health Action Process Approach Based Intervention on Sedentary Behaviour and Stress in Office Workers
Status: COMPLETED
Conditions: Sedentary Behavior|Health Behaviour Change|Perceived Stress
Interventions: BEHAVIORAL: HAPA behavioural counselling + weekly HAPA worksheets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RANKL Antibody for Acute Charcot Neuro-osteoarthropathy
Status: COMPLETED
Conditions: Charcot Joint of Foot
Interventions: DRUG: Danosumab|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Cerebral Vasospasm
Interventions: PROCEDURE: Stellate Ganglion Block|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Text2Breathe: Enhance Parent Communication to Reduce Pediatric Asthma Disparities
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Text2Breathe Study Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methanesulfonic Acid Cinepazide Injection for Treatment of Acute Cerebral Infarction
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: cinepazide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Booster Dose of BoostrixTM Polio Vaccine in Previously Boosted Adults
Status: COMPLETED
Conditions: Acellular Pertussis|Poliomyelitis|Diphtheria|Tetanus
Interventions: BIOLOGICAL: BoostrixTM Polio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring
Status: RECRUITING
Conditions: Prostate Carcinoma
Interventions: DRUG: Placebo Administration|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Sinecatechins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy (IgAN)
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: irbesartan|DRUG: methylprednisolone (MP) or prednisone (pred)|DRUG: mycophenolate mofetil (MMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation in Vivo of Dentifrice With Nanoencapsulated Fluoride
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Dentifrice 100% Nano-F|OTHER: Dentifrice 50% Nano-F|OTHER: Dentifrice standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: LPHP-Philos-PHN Conservative Treatment
Status: COMPLETED
Conditions: Proximal Humeral Fracture
Interventions: DEVICE: Locking proximal humerus plate|DEVICE: Proximal Humerus Internal Locking System|DEVICE: Proximal Humerus Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPI-613 and Docetaxel in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Stage IIIB Non-Small Cell Lung Cancer AJCC v7|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: DRUG: 6,8-Bis(benzylthio)octanoic Acid|DRUG: Docetaxel|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Pilot Study of a mHealth App for Ambivalent Smokers Living With HIV
Status: COMPLETED
Conditions: Smoking|Smoking Cessation
Interventions: DEVICE: mHealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis|Atopic Dermatitis
Interventions: DEVICE: CT-100-004-A|DEVICE: CT-100-004-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing 30mL Single Versus 80mL Double Balloon Catheters for Pre-induction Cervical Ripening
Status: COMPLETED
Conditions: Pre-induction Cervical Ripening
Interventions: DEVICE: mechanical pre-induction cervical ripening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cloretazine (VNP40101M) With Hematopoietic Cell Transplantation for Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Cloretazine|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Additional Chemotherapy and/or Radiation Therapy in Treating Children With Newly Diagnosed Hodgkin's Disease
Status: COMPLETED
Conditions: Childhood Lymphocyte-Depleted Classical Hodgkin Lymphoma|Childhood Mixed Cellularity Classical Hodgkin Lymphoma|Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma|Childhood Nodular Sclerosis Classical Hodgkin Lymphoma|Stage I Childhood Hodgkin Lymphoma|Stage II Childhood Hodgkin Lymphoma|Stage III Childhood Hodgkin Lymphoma|Stage IV Childhood Hodgkin Lymphoma
Interventions: BIOLOGICAL: Bleomycin Sulfate|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|BIOLOGICAL: Filgrastim|RADIATION: Involved-Field Radiation Therapy|DRUG: Prednisone|DRUG: Vincristine Sulfate Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Renal Progenitors and Polyploid Tubular Cell Response in Glomerular and Tubular Diseases
Status: RECRUITING
Conditions: Nephropathy
Interventions: OTHER: Study of renal progenitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Response to the Neoadjuvant Chemotherapy for Advanced Ovarian Cancer by Multimodal Functional Imaging
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DEVICE: Functional Imaging previous the second course|DEVICE: Functional Imaging previous the surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Oropharynx|HPV
Interventions: DRUG: Cetuximab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Jejunal Interposition Improve Nutritional Status After Total Gastrectomy
Status: UNKNOWN
Conditions: Gastric Cancer|Nutrition Disorders
Interventions: PROCEDURE: Functional Jejunal Interposition|PROCEDURE: Roux-en-Y
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
Status: RECRUITING
Conditions: Child Maltreatment|Interpersonal Relations|Victimisation|Psychopathology|Electrocardiography
Interventions: BEHAVIORAL: Debrief
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Infertility
Interventions: DRUG: Triptorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Measurement of Microcirculation and Other Parameters With the Vital USA VitalDetect™ in Patients With Diabetes Mellitus Type 1 and Type 2 Versus Healthy Participants
Status: SUSPENDED
Conditions: Diabetes Mellitus
Interventions: DEVICE: VitalDetect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression
Status: TERMINATED
Conditions: Bipolar Disorder|Postpartum Depression
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COSIMA: COronary SInus Reducer for the Treatment of Refractory Microvascular Angina
Status: RECRUITING
Conditions: Coronary Microvascular Disease|Refractory Angina
Interventions: DEVICE: Coronary sinus reducer|OTHER: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antimicrobial Catheter Lock
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: Heparin 1000U/mL|DRUG: 4% Sodium Citrate with Gentamicin 320 mcg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial of Perioperative Chemotherapy (Gemcitabine and Cisplatin) and Adjuvant Chemoradiotherapy (With Weekly Low Dose Gemcitabine) in Patients With Lung Cancer With Positive Nodes
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin|PROCEDURE: radical surgery|PROCEDURE: chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Department-Initiated Medications for Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Naltrexone Pill|DRUG: Naltrexone Injection|BEHAVIORAL: Brief Negotiation Interview|DRUG: Gabapentin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Implantable Hemodynamic Monitor (Chronicle® IHM), and IHM in combination with single chamber ICD (Chronicle ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Sarcosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSA/HS) Using Nasal Continuous Positive Airway Pressure (nCPAP) Therapy (0249-015)
Status: TERMINATED
Conditions: Sleep Apnea, Obstructive|Hypopnea Syndrome|Excessive Daytime Sleepiness
Interventions: DRUG: Comparator: MK0249|DRUG: Comparator: placebo|DRUG: Comparator: modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron Absorption From Rice Fortified With Ferric Pyrophosphate
Status: COMPLETED
Conditions: Iron Deficiency|Anemia|Iron Deficiency Anemia
Interventions: OTHER: Administration of rice fortified with regular FePP|OTHER: Administration of rice fortified with regular FePP with citrate added during extrusion|OTHER: Administration of rice fortified with regular FePP and citrate added at consumption|OTHER: Administration of rice fortified with ferrous sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Adverse Effect of Prolonged Methylphenidate Treatment on Cardiac Functions
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity|Attention Deficit Disorder|Attention Deficit Hyperactivity Disorder|Attention Deficit Disorders With Hyperactivity|Attention Deficit Hyperactivity Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: Genetic Testing and Counseling|BEHAVIORAL: Screening Form
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pilot Study of Preoperative Intestinal Training Using Antegrade Ileostomy Infusion
Status: NOT_YET_RECRUITING
Conditions: Stoma Ileostomy|Ileostomy; Complications
Interventions: OTHER: ileostomy infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Trial Using Lithium As A Neuroprotective Agent In Patients Undergoing Prophylactic Cranial Irradiation For Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced IV Fluids to Improve Clearance of HDMTX in Children w/Lymphoma or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Lymphoma|Acute Lymphoblastic Leukemia|Pediatric Cancer|Pediatric ALL|Pediatric Lymphoma
Interventions: DRUG: Intravenous fluids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ketorolac in Breast Cancer Surgery
Status: COMPLETED
Conditions: Curative Breast Cancer Surgery|Inflammatory Positive/Negative Status|Pre Surgical Incision Administration
Interventions: DRUG: Ketorolac 30 mg IV|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biometric Factors Changes Caused by Myopia Orthokeratology (OK) Lens
Status: UNKNOWN
Conditions: Contact Lenses
Interventions: DEVICE: Overnight orthokeratology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Using 50 ml Syringe Manual Thrombectomy Catheter in Primary PCI With Heavy Thrombus Burden
Status: NOT_YET_RECRUITING
Conditions: STEMI - ST Elevation Myocardial Infarction|Thrombosis Cardiac
Interventions: DEVICE: 30 mL syringe manual thrombectomy catheter|DEVICE: 50 mL syringe manual thrombectomy catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Follow-up of Patients With Implantable Cardioverter Defibrillators by Home Monitoring (ANVITE)
Status: TERMINATED
Conditions: Cardiac Pacing|Electric Countershock|Ventricular Tachyarrhythmia
Interventions: DEVICE: Implantable cardioverter defibrillator with Home Monitoring function|DEVICE: Standard implantable cardioverter defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Perineural Clonidine Prolong Duration of a Nerve Block?
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ropivacaine 20ml 5mg/ml+ Clonidine 150ug|DRUG: Ropivacaine 20ml 5mg/ml+ Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Breast Cancer|Hepatocellular Carcinoma
Interventions: DRUG: Piflufolastat F18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Safety and Efficacy of Using Venus Freeze™ (MP)2 V2 System for Wrinkles Rhytides and Cellulite Treatment
Status: COMPLETED
Conditions: Wrinkled Structure|Circumference Reduction
Interventions: DEVICE: Venus Freeze (MP2 V2 System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Melanoma
Status: TERMINATED
Conditions: Metastatic Cancer|Metastatic Melanoma
Interventions: BIOLOGICAL: Anti-NY ESO-1 T cell receptor (TCR) cluster of differentiation 62L (CD62L)+ cells|DRUG: Aldesleukin|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lot Consistency Study of COVID-19 and Influenza Combination Vaccine
Status: NOT_YET_RECRUITING
Conditions: COVID-19|Influenza
Interventions: BIOLOGICAL: coformulated CIC Vaccine|BIOLOGICAL: Fluzone HD trivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Community-based Implementation Model for HIV Prevention and Testing in Malawi
Status: COMPLETED
Conditions: HIV CDC Category A1
Interventions: BEHAVIORAL: Mzake ndi Mzake T1|BEHAVIORAL: Mzake ndi Mzake T2|BEHAVIORAL: Mzake ndi Mzake T3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis
Status: RECRUITING
Conditions: Atrial Fibrillation and Flutter|Stroke|Major Bleed|End-stage Renal Disease
Interventions: DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: XL888 + Vemurafenib + Cobimetinib for Unresectable BRAF Mutated Stage III/IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Skin Cancer
Interventions: DRUG: XL888|DRUG: Vemurafenib|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin Intervention For Neurocognitive Deficits in the St. Jude Lifetime Cohort
Status: COMPLETED
Conditions: Cancer Malignancies
Interventions: DRUG: melatonin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validating Low FDG Dose PET/CT Compared to Current Standard of Care Dose PET/CT
Status: ACTIVE_NOT_RECRUITING
Conditions: PET/CT Imaging
Interventions: DIAGNOSTIC_TEST: PET/CT scan with 13 mCi radiation dose|DIAGNOSTIC_TEST: PET/CT scan with 5 mCi radiation dose|DIAGNOSTIC_TEST: PET/CT scan with 2.5 mCi radiation dose|DIAGNOSTIC_TEST: PET/CT Scan with 6.5 mCi radiation dose|DIAGNOSTIC_TEST: PET/CT Scan with not yet determined radiation dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nitrate and Hypertension in Heart Transplanted Patients
Status: COMPLETED
Conditions: Hypertension|Heart Transplantation
Interventions: DRUG: acute infusion of nitroglycerine into the pulmonary artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photo Biostimulation and Spasticity in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Cerebral Palsy, Spastic
Interventions: OTHER: photo biostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia
Status: COMPLETED
Conditions: Falciparum Malaria|Vivax Malaria
Interventions: DRUG: Chloroquine and sulphadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling, Manual Therapy and Exercise for Neck Pain Management
Status: RECRUITING
Conditions: Neck Pain, Posterior
Interventions: OTHER: Dry Needling|BEHAVIORAL: Therapeutic Exercise|OTHER: Manual Therapy|OTHER: Sham Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study With Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (CHOP) in Patients With Gastric Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Primary Gastric Diffuse-Large B-Cell Lymphoma
Interventions: DRUG: Rituximab + CHOP chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Lansoprazole in Patients With Frequent Nighttime Heartburn
Status: COMPLETED
Conditions: Frequent Heartburn
Interventions: DRUG: Lansoprazole|DRUG: Lansoprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT