pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: "Eat Right Now" (ERN) mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Riociguat for Chronic Thromboembolic Pulmonary Hypertension (CTEPH )
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (ADEMPAS, BAY63-2521)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-Esophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: CS1001 monoclonal antibody|DRUG: CS1001 placebo|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cancer Peptides Vaccine Plus GM-CSF as Adjuvant Treatment for High Risk (TXN2-3M0) or Metastatic Breast Cancer With No Evidence of Disease
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: OCPM Immunotherapeutic Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Similarities of Tinnitus and PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Tinnitus
Interventions: DIAGNOSTIC_TEST: resting-state functional MRI|DIAGNOSTIC_TEST: Clinician Administered PTSD Scale for the DSM-5 (CAPS-5)|DIAGNOSTIC_TEST: Tympanometry|DIAGNOSTIC_TEST: Tinnitus Assessment|DIAGNOSTIC_TEST: Otoscopy|DIAGNOSTIC_TEST: Pure tone air and bone-conduction|DIAGNOSTIC_TEST: Speech testing|DIAGNOSTIC_TEST: Loudness Discomfort|DIAGNOSTIC_TEST: Quick Speech in Noise Test|DIAGNOSTIC_TEST: Distortion-Product Otoacoustic Emissions (DPOAE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transplacental Gradients and Transport in Intrauterine Growth Restricted (IUGR) Pregnancies Compared to Normal Pregnancies.
Status: TERMINATED
Conditions: IUGR|Pregnancy
Interventions: DRUG: Mannose|DRUG: Myoinositol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Regimen Switch to Dolutegravir + Rilpivirine From Current Antiretroviral Regimen in Human Immunodeficiency Virus Type 1 Infected and Virologically Suppressed Adults (SWORD-1)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: DTG 50 mg|DRUG: RPV 25 mg|DRUG: CAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Quadratus Lumborum Block Versus Caudal Block in Pediatric Patient
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus lumborum block|PROCEDURE: Caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoparathyroidism|Endocrine System Diseases|Parathyroid Diseases
Interventions: COMBINATION_PRODUCT: TransCon PTH|COMBINATION_PRODUCT: Placebo for TransCon PTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study
Status: RECRUITING
Conditions: COPD
Interventions: DRUG: Beclometasone/Formoterol/Glycopyrronium 88 µg/5 µg/9 µg DPI (Trimbow® 88 µg/5 µg/9 µg in NEXThaler device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nursing Intervention Program in the Management of Parental Anxiety and Infant Pain in the Surgical Process of Children to be Circumcised
Status: COMPLETED
Conditions: Anxiety|Pain, Postoperative|Child Development
Interventions: BEHAVIORAL: Intervention group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Monitoring Messenger: Mobile Patient Monitoring for the Pediatric Intensive Care Unit
Status: WITHDRAWN
Conditions: Medical Device|User-Computer Interface|Critical Care|Physiologic Monitoring
Interventions: DEVICE: Monitoring Messenger|DEVICE: Traditional tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exercise for Patients With Heart Failure in Primary Care: the EFICAR
Status: UNKNOWN
Conditions: Heart Failure
Interventions: BEHAVIORAL: Supervised progressive exercise program with an aerobic and a strength component + Optimized treatment|BEHAVIORAL: Optimized treatment according to the European Society of Cardiology guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism (MAJIK)
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Inflammatory Rheumatism|Psoriatic Arthritis|Spondyloarthritis
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM
Status: UNKNOWN
Conditions: HPV - Anogenital Human Papilloma Virus Infection|HSIL, High Grade Squamous Intraepithelial Lesions|Anal Cancer|Hiv
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Versus Low Level of Lumbar Traction in Acute Lumbar Sciatica Due to Disc Herniation
Status: COMPLETED
Conditions: Acute Lumbar Sciatica Secondary to Disc Herniation
Interventions: PROCEDURE: Traction sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Inverted Periosteal Pedicle Flap in Treatment of Gingival Recession
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: Inverted periosteal pedicle flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
Status: RECRUITING
Conditions: Finger Tip Amputations
Interventions: PROCEDURE: The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Bread Diet on Intestinal Dysbiosis and Irritable Bowel Syndrome Symptoms in Quiescent Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis in Remission
Interventions: DIETARY_SUPPLEMENT: Treatment vs control bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm
Interventions: DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: Cataract surgery combined with ab-interno canaloplasty utililzing the iTrack Advance canaloplasty device|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open Label, Single Dose Study to Evaluate the Effect of Renal Insufficiency on the Pharmacokinetics of SK 0403
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SK-0403
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The Clinical Role of Intravenous Glutamine in Trauma Patients Receiving Enteral Nutrition
Status: UNKNOWN
Conditions: Multiple Trauma|Critically Ill
Interventions: DIETARY_SUPPLEMENT: Dipeptiven|DIETARY_SUPPLEMENT: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apapitatin Combined With SOX for Palliative Adjuvant Chemotherapy in Patients With Advanced Gallbladder Carcinoma
Status: UNKNOWN
Conditions: Gallbladder Carcinoma
Interventions: DRUG: Apatinib|DRUG: Tegafur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Bevacizumab|DRUG: Metronomic Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin and Cyclophosphamide Followed by Paclitaxel, Trastuzumab, and Lapatinib in Treating Patients With HER2/Neu-Overexpressed Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: lapatinib ditosylate|DRUG: paclitaxel|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Coronary Syndrome KCMC_1
Status: NOT_YET_RECRUITING
Conditions: Hypertension|HIV
Interventions: BEHAVIORAL: Community Health Worker (CHW)-delivered Hypertension Management Pilot (CHAMP)|BEHAVIORAL: Control of Blood Pressure and Risk Attenuation (COBRA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease
Status: RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease|Coronary Artery Disease|Ischemic Heart Disease|Ischemic Stroke|Peripheral Arterial Disease|Carotid Artery Stenosis|Carotid Atherosclerosis
Interventions: DRUG: Enteric-coated aspirin|DRUG: Plain aspirin|OTHER: Hybrid strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Steady-state Efavirenz 600 mg QD (Sustiva®) on Tipranavir Concentration at Steady-state in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Simvastatin Plus Omacor Compared to Simvastatin Plus Placebo in Subjects With Mixed Dyslipidemia
Status: COMPLETED
Conditions: Mixed Dyslipidemia
Interventions: DRUG: Omacor (omega-3-acid ethyl esters)plus simvastatin|DRUG: simvastatin plus placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Trial of Aggressive Hydration Strategy to Reduce Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: lactated Ringer's solution (vigorous hydration arm)|DRUG: lactated Ringer's solution (standard hydration arm)|DEVICE: endoscopic retrograde cholangiopancreatography (ERCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
Status: COMPLETED
Conditions: Spinal Tumor|Traumatic Injury of Spine|Degenerative Spine Disease
Interventions: DEVICE: "Anatase" Spine Surgery Navigation System|DEVICE: Medtronic Stealthstation S7 Treatment Guidance System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, With Complications
Interventions: PROCEDURE: Effect of Pulsatile IV insulin on diabetic neuropathy|PROCEDURE: Effect of Pulsatile IV Insulin on diabetic neuropathy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Infraclavicular and Axillary Approaches for Continuous Ultrasound-guided Brachial Plexus Block.
Status: WITHDRAWN
Conditions: Anesthesia, Regional|Brachial Plexus Block
Interventions: PROCEDURE: Hand surgery under regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MRI in Diagnosing Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: OTHER: biologic sample preservation procedure|OTHER: laboratory biomarker analysis|OTHER: study of socioeconomic and demographic variables|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: multiparametric magnetic resonance imaging|PROCEDURE: quality-of-life assessment|PROCEDURE: transperineal prostate biopsy|PROCEDURE: transrectal prostate biopsy|PROCEDURE: ultrasound-guided prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of INCAGN01876 in Participants With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignancies|Metastatic Cancer
Interventions: DRUG: INCAGN01876
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genotoxicity Assessment of Dental Implants in Gingival Epithelial Cells
Status: UNKNOWN
Conditions: Genotoxicity
Interventions: PROCEDURE: implant placement|PROCEDURE: gingiva former placement|DIAGNOSTIC_TEST: Collecting gingival epithelial cellsusing the swab technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: C-Met Exon 14 Mutation
Interventions: DRUG: Glumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SOR007 Ointment for Cervical Intraepithelial Neoplasia (CIN)
Status: WITHDRAWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: SOR007 (Uncoated Nanoparticulate Paclitaxel) Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of GX-H9 in Paeditaric Patients With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: GX-H9|DRUG: Genotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: prednisone group|DRUG: Advair group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Mini Approach vs Anterior Approach for Plating of Proximal Humerus Fracture
Status: COMPLETED
Conditions: Closed Fracture Proximal Humerus, Neck
Interventions: PROCEDURE: Lateral minimally invasive approach (plate fixation)|PROCEDURE: Deltopectoral approach (plate fixation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study for the Treatment of Primary Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DEVICE: Placement of Snowshoe Suture Anchors|BEHAVIORAL: Moderate Intensity Diet & Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration Training on Functional Performance of the Elderly With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: OTHER: Addition of whole-body vibration to squat training|OTHER: Squat training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromagnetic Field Versus Diclofenac Drugs on Primary Dysmenorrhea
Status: COMPLETED
Conditions: Electromagnetic Field|Dysmenorrhea
Interventions: DEVICE: Pulsed electromagnetic field|DRUG: diclofenac tablets|DIAGNOSTIC_TEST: Visual analogue scale|DIAGNOSTIC_TEST: Progesterone blood level|DIAGNOSTIC_TEST: Menstrual symptom questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REsearching Coronary REduction by Appropriately Targeting Euglycemia (RECREATE Pilot Study)
Status: COMPLETED
Conditions: Hyperglycemia|Cardiovascular Diseases|Myocardial Infarction
Interventions: DRUG: glulisine insulin, glargine insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Epidural Anesthesia on the Intra-operative and Post-operative Amount of Bleeding Post Lower Limb Salvage Surgery
Status: WITHDRAWN
Conditions: Bone Tumor
Interventions: OTHER: epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use|Smoking Cessation|Nicotine Dependence
Interventions: DRUG: Ketamine Hydrochloride|BEHAVIORAL: Motivational enhancement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collecting Respiratory Sound Samples From Corona Patients to Extend the Diagnostic Capability of VOQX Electronic Stethoscope to Diagnose COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: Electronic stethoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: XL888|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone Secretagogue MK-0677 Effect on IGF-1 Levels in ESRD Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease|End Stage Renal Disease
Interventions: DRUG: MK-0677|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aachen Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device to Reduce Mitral Regurgitation
Status: COMPLETED
Conditions: Heart Failure|Mitral Regurgitation
Interventions: DEVICE: PTMA Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TJ202, Lenalidomide and Dexamethasone vs. Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse|Refractory Multiple Myeloma
Interventions: DRUG: TJ202, Lenalidomide and Dexamethasone|DRUG: Lenalidomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGNAM Trial, Magnesium Versus Amiodarone in Atrial Fibrillation in Critical Care
Status: RECRUITING
Conditions: Atrial Fibrillation New Onset
Interventions: DRUG: Magnesium sulfate and then Digoxin|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: Doxycycline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bupivacaine Liposome Injection in Local Analgesia of Pediatric Patients
Status: RECRUITING
Conditions: Local Analgesia Via Infiltration
Interventions: DRUG: Bupivacaine Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Repetitive Transcranial Magnetic Stimulation for First-episode Schizophrenia Patients
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: OTHER: active Risperidone and active rTMS|OTHER: active rTMS and sham Risperidone|OTHER: sham rTMS and active Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Placebo-Controlled Trial of Albendazole in HIV-Positive Patients With Intestinal Microsporidiosis
Status: COMPLETED
Conditions: Protozoan Infections|HIV Infections
Interventions: DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Valproic acid|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Traditional and Computerized Versions of Super Skills for Life in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Disorder|Depressive Symptoms|Anxiety Disorders|Anxiety Disorders and Symptoms|Mood Disorders|Emotional Disorder
Interventions: BEHAVIORAL: Super Skills for Life: traditional version|BEHAVIORAL: Super Skills for Life: computerized version
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy/Safety of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder (HSDD)
Interventions: DRUG: Testosterone Transdermal System|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide
Status: UNKNOWN
Conditions: Ventilation Perfusion Mismatch
Interventions: OTHER: Arterial carbon dioxide monitoring|OTHER: End-tidal carbon dioxide monitoring|OTHER: Transcutaneous carbon dioxide monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Affects of Different Vertebral Manipulation Techniques on Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Lomber roll techniques group (n=23)|OTHER: Posterior- anterior central vertebral manipulation techniques (n=23)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustainable Reduction of Dengue in Colombia: Vector Breeding Site Intervention With an Insecticidal Coating
Status: COMPLETED
Conditions: Dengue|Vector Borne Diseases|Arbovirus Infections|Zika|Chikungunya Fever
Interventions: OTHER: Insecticide Coating INESFLY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Osteoconduction Potential of an Injectable Calcium Phosphate in Orthopaedic Surgery in Fillings of Osseous Defects
Status: UNKNOWN
Conditions: Grafting, Bone
Interventions: DEVICE: MBCP-Gel (tm)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Study of Effects of Nasal Insulin on Memory
Status: COMPLETED
Conditions: Human Memory|Intranasal Insulin
Interventions: DRUG: Intranasal Insulin|DRUG: Intranasal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload
Status: COMPLETED
Conditions: Thalassemia|Sickle Cell Disease|Diamond Blackfan Anemia|Myelofibrosis
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Pegol-Sihematide for Anemia in Patients With Chronic Kidney Disease on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: Pegol-Sihematide|DRUG: ESPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma
Status: TERMINATED
Conditions: Effect of Sitaxsentan on Airway Remodeling in Severe Asthma
Interventions: DRUG: sitaxentan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrically Guided Bachmann's Bundle Pacing: A Lead Placement Strategy With Potential Antiarrhythmic Benefits
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Bachmann's bundle lead placement|PROCEDURE: Right atrial appendage lead placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating The Safety, Efficacy & Pharmacokinetics Of Temsirolimus(CCI-779) In Subjects With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Temsirolimus (CCI-779)|DRUG: Temsirolimus (CCI-779)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Tiotropium Inhalation Capsules vs Placebo in Chronic Obstructive Pulmonary Disease (COPD).
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AM-111 in the Treatment of Acute Inner Ear Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Placebo|DRUG: AM-111 0.4 mg/ml|DRUG: AM-111 0.8 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus SOX as Neoadjuvant Therapy for Locally Advanced Gastric Adenocarcinoma
Status: RECRUITING
Conditions: Gastric Cancer|GastroEsophageal Cancer|Fruquintinib|SOX
Interventions: DRUG: Fruquintinib + SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of ER:YAG Laser, CO2 Laser and Scalpel Excision of Fibrous Hyperplasia on the Buccal Mucosa
Status: COMPLETED
Conditions: Fibrous Hyperplasia on Oral Mucosa
Interventions: PROCEDURE: Excisional biopsy with Er:YAG laser|PROCEDURE: Excisional biopsy with CO2 laser|PROCEDURE: Excisional biopsy with scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)
Status: COMPLETED
Conditions: Primary Focal Segmental Glomerulosclerosis
Interventions: DRUG: fresolimumab|DRUG: fresolimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enfortumab Vedotin as Monotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Enfortumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Low Level Laser Therapy and Kabat Technique in Patients With Bell's Palsy
Status: RECRUITING
Conditions: Bell Palsy
Interventions: OTHER: Kabat Technique along with baseline treatment|DEVICE: Kabat Technique and LLLT along with baseline treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate AZR-MD-001 in Patients With Abnormal Meibomian Gland Function and Dry Eye Disease (DED)
Status: RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: AZR-MD-001|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Naps on Decision Making of Residents.
Status: COMPLETED
Conditions: Internship and Residency|Sleep|Decision Making
Interventions: BEHAVIORAL: nap from 0:00 to 3:00 hours|BEHAVIORAL: nap from 3:00 to 6:00 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Status: COMPLETED
Conditions: Muscle Damage
Interventions: OTHER: Strength Training with Caffeine|OTHER: Endurance Training with Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Parent Intervention to Reduce College Student Drinking and Consequences
Status: COMPLETED
Conditions: Underage Drinking|Driving Under the Influence|Drinking, Teen|Drinking, College
Interventions: BEHAVIORAL: P-Chat|BEHAVIORAL: PBI|BEHAVIORAL: P-Chat+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Developing and Implementing an Adolescent Suicide Prevention Program in a Community Mental Health Setting
Status: COMPLETED
Conditions: Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Suicide Prevention Intensive Outpatient Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Ascending Dose Study of CTI-1601 Versus Placebo in Subjects With Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: BIOLOGICAL: CTI-1601|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and Microalbuminuria
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DRUG: colchicine 0.5mg/d|DRUG: placebo 0.5mg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 177Lu-Anti-ED-B mAbs SPECT Imaging in Patients With ED-B Positive Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: 177Lu-B5-IgG4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tissue Perfusion for Different Approaches of Brachial Plexus Block
Status: COMPLETED
Conditions: Upper Extremity Fracture|Regional Anesthesia|Brachial Plexus Blocks|Perfusion Index|Tissue Perfusion
Interventions: OTHER: Lateral sagittal approach|OTHER: Costoclavicular approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Additive Omega-3 Fish Oil to Palliative Chemotherapy to Treat Oesophagogastric Cancer
Status: TERMINATED
Conditions: Esophageal Neoplasm|Gastric Neoplasm
Interventions: DRUG: Omegaven
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct
Status: UNKNOWN
Conditions: Acute ST Segment Elevation Myocardial Infarction
Interventions: DEVICE: stent implant in a coronary artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Dependent Effects of Anthocyanins on Endothelial Function in Healthy Men
Status: COMPLETED
Conditions: Healthy Men
Interventions: DIETARY_SUPPLEMENT: anthocyanins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Purpose of the Study is to Continue to Provide Pemigatinib to Patients With Advanced Malignancies.
Status: TERMINATED
Conditions: Advanced Malignancies
Interventions: DRUG: Pemigatinib|DRUG: Retifanlimab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Treatment of Gastroesophageal Reflux Disease
Status: ENROLLING_BY_INVITATION
Conditions: Gastro Esophageal Reflux Disease
Interventions: OTHER: Endoscopic mucosal band ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Intravenous and Subcutaneous Administration of a Human Monoclonal Antibody (CNTO 5825) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825|BIOLOGICAL: CNTO 5825
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate
Status: TERMINATED
Conditions: Cleft Palate|Tube Disorders Eustachian|Velopharyngeal Incompetence Due to Cleft Palate|Velopharyngeal Insufficiency
Interventions: DEVICE: EMST150
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Verify if Tranexamic Acid Can Reduce the Anemia After a Femoral Shaft Fractures Surgery
Status: WITHDRAWN
Conditions: Femoral Shaft Fracture
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SPARC1203 in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: SPARC1203|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypercapnia on Emergence From General Anesthesia Under Propofol
Status: COMPLETED
Conditions: Anesthesia, Intravenous|Anesthesia Recovery Period
Interventions: PROCEDURE: Rebreathing tube|PROCEDURE: No rebreathing tube (Nothing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients
Status: UNKNOWN
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DRUG: AXS-05|DRUG: Bupropion SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Eluxadoline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Convalescent Plasma to Treat COVID-19 Patients, a Nested Trial in the CORIMUNO-19 Cohort
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Transfusion of COVID-19 convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation
Interventions: DRUG: ganirelix|DRUG: triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory Ascites
Status: COMPLETED
Conditions: Cirrhosis|Ascites Hepatic
Interventions: DRUG: Terlipressin acetate continuous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic's Disease)
Status: COMPLETED
Conditions: Neuromyelitis Optica|Myelitis, Transverse|Demyelinating Autoimmune Diseases, CNS|Autoimmune Diseases of the Nervous System
Interventions: DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males
Status: COMPLETED
Conditions: Hypotension|Spinal Cord Injury
Interventions: DRUG: tadalafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Flibanserin From AphroFemine 100 mg F.C.T (Bio Med for Pharmaceuticals Industries (BIOMED), Egypt) Versus Addyi 100 mg Tablets (Sprout Pharmaceuticals, Inc., USA)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Flibanserin 100Mg Tab|DRUG: Flibanserin 100 MG [Addyi]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Avatrombopag on the Treatment of Thrombocytopenia Induced by Chemotherapy of Malignant Tumors
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DRUG: Avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discomfort and Psychosocial Difficulties in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Botox infiltration|BEHAVIORAL: Psychology therapy|OTHER: Botox infiltration & psychology therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|BIOLOGICAL: Magrolimab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of KF-0210 in Advanced Solid Tumors Patients
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Colorectal Cancer|Lung Cancer|Squamous Cell Carcinoma of the Esophagus|Gastric Cancer|Bladder Cancer
Interventions: DRUG: KF-0210 tablets, 120 mg|DRUG: KF-0210 tablets, 240 mg|DRUG: KF-0210 tablets, 450 mg|DRUG: KF-0210 tablets, 600 mg|DRUG: KF-0210 (dosage RP2D-2) + Atezolizumab|DRUG: KF-0210 (dosage RP2D-1) + Atezolizumab|DRUG: KF-0210 (dosage RP2D) + Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs (REMISSION)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Concomitant Cisplatin Versus Carboplatin and 5-fluorouracil With Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: cisplatin|DRUG: carboplatin|DRUG: 5-FU
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lung Cancer in Women Treated With Anti-oestrogens anD Inhibitors of EGFR
Status: COMPLETED
Conditions: Stage IV Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Fulvestrant|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Treatment in Vascular Parkinsonism
Status: NOT_YET_RECRUITING
Conditions: Vascular Parkinsonism
Interventions: DEVICE: Real rTMS Supplementary motor area|DEVICE: Sham rTMS Supplementary motor area
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop
Status: COMPLETED
Conditions: Myopia, Progressive
Interventions: DRUG: CBT-009|DRUG: Vehicle|DRUG: Atropine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction , Prosthetic Complications and Clinical Outcomes of PEEK Composite Versus Titanium Zirconium
Status: COMPLETED
Conditions: Patient Satisfaction|Prosthetic Complication|Clinical Outcomes
Interventions: DEVICE: Osstell® device (Integration Diagnostics Ltd.).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sodium Fluoride PET in the Identification of Bone Metastases in Patients Having Undergone a Choline PET for Occult Recurrence of Prostatic Adenocarcinoma
Status: UNKNOWN
Conditions: Bone Metastasis
Interventions: PROCEDURE: Sodium fluoride PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC