pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: I-gel vs LMA Supreme in Laparoscopic Gynecological Surgery
Status: COMPLETED
Conditions: Airway Morbidity|Anaesthesia
Interventions: DEVICE: Laryngeal mask Supreme Evaluation|DEVICE: i-gel Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MoodHelper: Internet Cognitive Behavioral Therapy (CBT) for Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Pure self-help Internet CBT for depression|BEHAVIORAL: Guided self-help Internet CBT|BEHAVIORAL: Stepped-Care Internet CBT condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Solifenacin in the Treatment of OAB Symptoms in Patients Who Have Successfully Undergone GreenLight Photoselective Vaporization of the Prostate (PVP)
Status: UNKNOWN
Conditions: Urinary Frequency|Urinary Urgency|Nocturia
Interventions: DRUG: Solifenacin PO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Administration of Teripapartide and Antiresorptive Agents in Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: teriparatide|DRUG: teriparatide and raloxifene|DRUG: teriparatide and alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of the Healing of Chronic Ulcers of Recessive Epidermolysis Bullosa : Dressing vs Amniotic Membrane
Status: UNKNOWN
Conditions: Epidermolysis Bullosa Dystrophica, Recessive|Ulcer
Interventions: DEVICE: Amniotic Membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ginger in the Prevention of Abdominal Distention in Post Cesarean Section Patient
Status: COMPLETED
Conditions: Post Cesarean Section Patient
Interventions: DRUG: Ginger|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Home-exercise Programs Versus Supervised Core Stability Exercises on Hypertensive Patient With Low Back Pain
Status: COMPLETED
Conditions: Hypertension|Low Back Pain
Interventions: OTHER: home exercise program|OTHER: the core stability exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and the Tolerance of an Omega 3 Fatty Acids Supplementation in ADHD Children
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Omega 3 caps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Obstructive Sleep Apnea Hypopnea Syndrome and Obesity Hypoventilation Syndrome (OHS)
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Obesity Hypoventilation Syndrome
Interventions: DEVICE: ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Technique of Massage During the First Week of Hospitalization on the Recycling of the Mobility of the Knee Further to the Installation of Knee Replacement
Status: COMPLETED
Conditions: Orthopedic Surgery
Interventions: OTHER: manual lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Detection of Atelectasis or Pneumothorax and Resolution With Electrical Impedance Tomography (EIT) in Newborn Infants
Status: COMPLETED
Conditions: Atelectasis Neonatal|Pneumothorax and Air Leak
Interventions: OTHER: Detecting asymmetric lung disease like atelectasis or pneumothorax with electrical impedance tomography (EIT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheumatoid Arthritis Enrolled in Study GA29350
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GDC-0853
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: pRotective vEntilation With Veno-venouS Lung assisT in Respiratory Failure
Status: UNKNOWN
Conditions: Acute Respiratory Failure With Hypoxia
Interventions: DEVICE: VV-ECCO2R to enable lower tidal volume mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PROACTIVE Study for Black Elders
Status: NOT_YET_RECRUITING
Conditions: Musculoskeletal Pain|Chronic Pain|Osteoarthritis|Pain, Chronic|Movement Evoked Pain
Interventions: BEHAVIORAL: PROACTIVE Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV Glioma
Status: RECRUITING
Conditions: Glioblastoma|WHO Grade II Glioma|WHO Grade III Glioma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Quality-of-Life
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Routine Versus Selective Use of Ultrasound Scanning Prior to Haemodialysis Fistula Surgery
Status: COMPLETED
Conditions: End Stage Renal Failure|Surgery
Interventions: PROCEDURE: Arterial and venous duplex ultrasound examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sympathetic and Blood Pressure Responses to Aerobic Exercise and Guided Respiration in Hypertensives
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Resperate®-InterCure Ltda|OTHER: Music group (GC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of S (+) - Ketamine in Children
Status: ENROLLING_BY_INVITATION
Conditions: S-ketamine|Esketamine|Acute Pain|Postoperative Pain|Analgesia|Hyperalgesia|Delirium|Depression, Anxiety|Children
Interventions: DRUG: Conventional therapy + S (+)-Ketamine|DRUG: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Clonidine Versus Corticosteroid for Low Back Pain
Status: TERMINATED
Conditions: Back Pain
Interventions: DRUG: Epidural steroid|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzastaurin and Bevacizumab in Treating Patients With Locally Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: bevacizumab|DRUG: enzastaurin hydrochloride|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olmesartan Medoxomil in Hypertension and Renal Impairment
Status: COMPLETED
Conditions: Essential Hypertension|Renal Impairment
Interventions: DRUG: Olmesartan medoxomil|DRUG: Losartan|DRUG: Furosemide oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for PCOS
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome (PCOS)|Polycystic Ovary Syndrome|PCOS
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- a Descriptive Study
Status: RECRUITING
Conditions: Out-of-Hospital Cardiac Arrest|Pulmonary Ventilation
Interventions: DEVICE: Fluxmed GrH will be used to measure the ventilation parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Acute Respiratory Disease|Myalgic Encephalomyelitis|Chronic Fatigue Syndrome|Post-acute Sequelae of SARS-COV-2 Infection|Post COVID-19 Condition
Interventions: OTHER: Extension for Community Healthcare Outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Zero Heat Flux Cutaneous Temperature in Intensive Care Adults
Status: COMPLETED
Conditions: Continuous Non Invasive Cutaneous Temperature|Zero Heat Flux Method|Esophageal Temperature|Arterial Temperature|Intracerebral Temperature
Interventions: PROCEDURE: temperature obtained by the non-invasive method of zero-heat flux|PROCEDURE: esophageal temperature|PROCEDURE: intracerebral temperature|PROCEDURE: arterial temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting
Status: UNKNOWN
Conditions: Caries; Initial|Pit and Fissure Caries
Interventions: PROCEDURE: Self etch Pit and fissure sealant application (prevent seal)|PROCEDURE: Self etch Pit and fissure sealant application (prevent seal) with prior sandblasting|PROCEDURE: Total etch resin based sealant ultraseal xt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immune System Function Following Vaccination in HIV Infected Children Taking Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Pneumococcal 7-valent conjugate vaccine|BIOLOGICAL: Pneumococcal polysaccharide vaccine|BIOLOGICAL: Hepatitis B vaccine|BIOLOGICAL: Measles, mumps, and rubella virus vaccine, live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Long-Term Physical Activity After Lumbar Spine Surgery
Status: RECRUITING
Conditions: Lumbar Spine Degenerative Changes
Interventions: BEHAVIORAL: Education/Self-efficacy|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fampridine-SR b.i.d. (Twice Daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nobori Dual Antiplatelet Therapy as Appropriate Duration
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Aspirin or thienopyridine|DRUG: Aspirin and thienopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: DRUG: Akt inhibitor MK2206|DRUG: selumetinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy
Status: RECRUITING
Conditions: Parathyroid Diseases|Parathyroid Dysfunction|Parathyroid Neoplasms|Parathyroid Adenoma|Hypercalcemia|Neoplasms, Glandular and Epithelial|Endocrine Gland Neoplasms|Adenoma|Hyperparathyroidism|Hyperparathyroidism, Primary
Interventions: DEVICE: Parathyroid Eye (PTeye)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: YOUhealTH - a Study to Improve Cardiovascular Health in Adolescents and Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Atherosclerosis
Interventions: BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)in Patients With Solid Tumours
Status: COMPLETED
Conditions: Melanoma|Cancer
Interventions: DRUG: CCT3833
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy
Status: UNKNOWN
Conditions: Ureterolithiasis|Nephrolithiasis
Interventions: DEVICE: Ureteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Grass Pollen Allergen Immunotherapy Tablet (AIT) Time Course Study
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Grazax|DRUG: Grazax Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age
Status: RECRUITING
Conditions: Neonatal Sepsis
Interventions: DRUG: Ceftobiprole medocaril
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Determination of 3D Patellofemoral Mechanics
Status: COMPLETED
Conditions: Arthroplasty Replacement Knee|Knee Prosthesis
Interventions: DEVICE: Subjects implanted with DePuy LCS PS RP TKA|DEVICE: Subjects implanted with DePuy Sigma PS RP TKA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment for Diabetic Neuropathy Using Repetitive Transcranial Magnetic Stimulation
Status: NOT_YET_RECRUITING
Conditions: Diabetic Neuropathies
Interventions: DEVICE: Sham Repetitive transcranial magnetic stimulation|DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle Pain
Status: ENROLLING_BY_INVITATION
Conditions: TMD
Interventions: DIAGNOSTIC_TEST: Diagnostic Criteria for Temporomandibular Disorders Clinical Examination|DIAGNOSTIC_TEST: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Propofol Versus Midazolam+Alfentanil for Sedation During Bronchoscopy: Comparison by Cutaneous Carbon Dioxide Tension
Status: COMPLETED
Conditions: Lung Disease
Interventions: DRUG: Sedation with Propofol or Midazolam+Alfentanil for FFB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toward a Safe and Reachable Preventive Therapy for LTBI: a Multicenter Randomized Controlled Study in Taiwan
Status: UNKNOWN
Conditions: Latent Tuberculosis Infection
Interventions: DRUG: Rifapentine and Isoniazid for 3 months|DRUG: Isoniazid for 9 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders
Status: COMPLETED
Conditions: Mood Disorder|Disruptive Behavior Disorders
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Cladribine in Treating Patients With Newly Diagnosed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transporter Cocktail Mutual Interaction
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Digoxin|DRUG: Furosemide|DRUG: Metformin|DRUG: Rosuvastatin|DRUG: Digoxin|DRUG: Furosemide|DRUG: Metformin hydrochloride|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: BIIL 284 BS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recovery of Bladder and Sexual Function After Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: Activity-based locomotor training|PROCEDURE: Activity-based stand training|PROCEDURE: Activity-based upper arm ergometry|PROCEDURE: Activity-based training + spinal epidural stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Screening of Autism Spectrum Disorder in General and Pediatric Practices
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: DIAGNOSTIC_TEST: early detection kit composed of 2 questionnaires (M-CHAT-R + CSBS-ITC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiological Changes Associated With Deqi During Electroacupuncture to Right LI4 and LI11
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: Electroacupuncture to right LI4 and LI11 (ITO, EX-160)|DEVICE: Sham Electroacupuncture to knee caps|DEVICE: Sham electroacupuncture to LI4 and LI11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapy in Amyotrophic Lateral Sclerosis (TAME)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Frontal Temporal Dementia
Interventions: DRUG: Memantine|DRUG: Placebo (for Memantine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A PET Imaging Agent to Assess the Level of Tumor Tissue-infiltrating CD8 + T Cells in Patients With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: 68Ga-NODAGA-SNA006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate|DRUG: Pyrimethamine|DRUG: Sulfamethoxazole/Trimethoprim|DRUG: Sulfadoxine/Pyrimethamine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neuroendocrine Tumor G1|Gastric Neuroendocrine Tumor G1|Neuroendocrine Neoplasm|Neuroendocrine Tumor|Neuroendocrine Tumor G2
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|DRUG: Octreotide Acetate|BIOLOGICAL: Recombinant Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Chagas Disease|Heart Failure
Interventions: DRUG: Sacubitril/valsartan|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Ability of Intra-Abdominal Pressure for Mortality in Patients With Severe Acute Pancreatitis
Status: COMPLETED
Conditions: Acute Pancreatitis|Intra-Abdominal Hypertension
Interventions: DIAGNOSTIC_TEST: intra-abdominal pressure in severe acute pancreatitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam Radiotherapy
Status: COMPLETED
Conditions: Biopsy Proven Non Small Cell Lung Cancer|Head and Neck Cancer|Gastrointestinal Cancer|Colorectal Cancer|Rectal Cancers|Gynecological Malignancy Requiring Definitive Radiotherapy
Interventions: DIAGNOSTIC_TEST: CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection
Status: RECRUITING
Conditions: Adenovirus|Primary Immune Deficiency Disorder
Interventions: DRUG: cytotoxic t-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Disease Management on Development of End Stage Renal Disease in Type 2 Diabetic Patients With Nephropathy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|DM Nephropathy
Interventions: BEHAVIORAL: Multidisciplinary team care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia
Status: UNKNOWN
Conditions: Relapsed Pediatric ALL|Acute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis)|Relapsed Pediatric AML
Interventions: PROCEDURE: In Vitro T cells depletion using CliniMCAS system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Guided Contouring of Craniofacial Fibrous Dysplasia Involving Zygoma
Status: UNKNOWN
Conditions: Craniofacial Fibrous Dysplasia
Interventions: PROCEDURE: Computer guided contouring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Role in the Treatment of Patients With Refractory or Relapse Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Nivolumab|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Elotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating Effects of Foliglurax in Patients With Parkinson's Disease (PD) and Healthy Subjects
Status: TERMINATED
Conditions: Parkinson Disease|Healthy
Interventions: DRUG: Foliglurax 10 mg (treatment A)|DRUG: Foliglurax 30 mg (treatment B)|DRUG: Placebo (treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Children Who Cannot Take Trimethoprim-Sulfamethoxazole
Status: COMPLETED
Conditions: Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pentamidine isethionate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Postoperative Infusion of Fibrinolysis Inhibitors After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Thoracic Surgery|Heart Diseases|Fibrinolysis Shutdown
Interventions: OTHER: No routine fibrinolysis inhibitors after surgery|OTHER: Routine fibrinolysis inhibitors after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short Versus Long Cephalomedullary Nailing of Pertrochanteric Hip Fractures: A Randomized Prospective Study
Status: COMPLETED
Conditions: Pertrochanteric Hip Fracture
Interventions: PROCEDURE: Short versus long cephalomedullary Intramedullary nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ropivacaine|DRUG: adrenaline|DRUG: ketorolac|DRUG: morphine|DRUG: fentanyl|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-efficacy Based Dietary Intervention
Status: TERMINATED
Conditions: Cancer
Interventions: BEHAVIORAL: Self-efficacy based images through instant messaging|BEHAVIORAL: Knowledge based images through instant messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Effects of Rosuvastatin 40mg on Myocardial Ischemia in Subjects With Coronary Artery Disease
Status: COMPLETED
Conditions: Myocardial Ischaemia|Coronary Artery Disease
Interventions: DRUG: Rosuvastatin|BEHAVIORAL: Cholesterol lowering diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atazanavir/Ritonavir and Zinc Pharmacokinetic Study
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: 1 Solvazinc tablet, day 2 to day 15|DRUG: 1 Solvazinc tablet, day 15 to day 28
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of BCD-145 (Anti-CTLA-4) in Patients With Unresectable/Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: BCD-145
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heated Breathing Circuit on Postoperative Sore Throat After Double-lumen Endobronchial Tube Insertion
Status: UNKNOWN
Conditions: Lung Surgery
Interventions: DEVICE: Heated breathing circuit on|DEVICE: Heated breathing circuit off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking for Compassionate Treatment in Pediatric Patients With Progressive Keratoconus
Status: UNKNOWN
Conditions: Progressive Keratoconus
Interventions: OTHER: Corneal collagen cross-linking with riboflavin/UVA light
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of tDCS in Intrinsic Functional Brain Connectivity Assessed by Functional Magnetic Resonance in Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DEVICE: Active-tDCS|DEVICE: Sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caspofungin Acetate in Treating Children With Fever and Neutropenia
Status: COMPLETED
Conditions: Fever, Sweats, and Hot Flashes|Infection|Kidney Cancer|Leukemia|Lymphoma|Neuroblastoma|Neutropenia|Sarcoma
Interventions: DRUG: caspofungin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ''Comparative Evaluation of Change in Bite Force and Levels of Bone Turnover Markers CTX and BALP in Hyperdivergent and Hypodivergent Cases During Retention Phases-A Prospective Clinical Trial ''
Status: RECRUITING
Conditions: Relapse|Bite Force|Biomarker
Interventions: OTHER: bite force and gcf in horizontal grower and vertical grower
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: Chronic Kidney Disease (CKD)|Secondary Hyperparathyroidism (SHPT)
Interventions: DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infection
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: DRUG: famciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)|Coronary Atherosclerosis
Interventions: DRUG: Placebo|DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ROsuvastatin Pretreatment to Reduce MyocArdial Periprocedural Necrosis:Comparison With Atorvastatin Reloading
Status: COMPLETED
Conditions: Assess the Periprocedural Myocardial Necrosis
Interventions: DRUG: ATORVASTATIN 80 mg|DRUG: ROSUVASTATIN 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satiation Study With Children Attending a Tertiary Feeding Clinic
Status: COMPLETED
Conditions: Undernutrition|Underweight
Interventions: BEHAVIORAL: High Energy preload|BEHAVIORAL: Low energy preload|BEHAVIORAL: Test meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Intervention With Potassium and/ or Magnesium-enriched Salt on Neurological Performance of Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Regular salt|OTHER: Potassium-enriched salt|OTHER: Potassium and magnesium-enriched salt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Combined Dexmedetomidine for Obturator Nerve Block
Status: COMPLETED
Conditions: Nerve Block
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isoprostane/FMD Study The Effect of Protein Kinase C (PKC) β Specific Inhibitor LY333531 on Oxidant Stress in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: ruboxistaurin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture or Metformin for Insulin Resistance in Women With PCOS
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Insulin Resistance|Hyperandrogenism
Interventions: OTHER: Lifestyle management|DEVICE: Acupuncture|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial Evaluating the Safety, Tolerability, and Pharmacokinetics of CU-40101 Liniment in Single and Multiple Doses in Adult Male Androgenic Alopecia Subjects
Status: RECRUITING
Conditions: AGA
Interventions: DRUG: CU-40101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Single Intramuscular Dose of Motavizumab to Treat Children With Respiratory Syncytial Virus (RSV) Illness
Status: TERMINATED
Conditions: Participants Less Than 12 Months of Age With RSV Illness
Interventions: BIOLOGICAL: Motavizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interval of Disease Inactivity After Complete Polypoidal Regression in PCV Receiving Aflibercept
Status: UNKNOWN
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Aflibercept Injection (2 mg/0.05 ml)|OTHER: Defer treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam in Central Pain in Multiple Sclerosis(MS)
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Radiotherapy for Oligometastatic Head and Neck Cancer
Status: NOT_YET_RECRUITING
Conditions: Oligometastatic Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Pembrolizumab|RADIATION: stereotattic ablation radiotherapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of mCRPC Patients Treated With Ra-223 Concomitant With Abiraterone or Enzalutamide- A Chart Review Study
Status: WITHDRAWN
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: radium Ra 223 dichloride (Xofigo, BAY88-8223)|DRUG: Zytiga|DRUG: Xtandi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Self-Amplifying Messenger Ribonucleic Acid (samRNA) Vaccines Against COVID-19 in Healthy Adults and People Living With Human Immunodeficiency Virus (HIV)
Status: COMPLETED
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: GRT-R912, samRNA-Spikebeta-TCE11|DRUG: GRT-R914, samRNA-Spikebeta-TCE9|DRUG: GRT-R918, samRNA-SpikeOmicron-N-TCE11
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients
Status: UNKNOWN
Conditions: Rosacea
Interventions: OTHER: Obtaining a blood sample|DEVICE: Reflectance confocal microscopy|DEVICE: Sebumeter|DEVICE: Video dermoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ib Study With Pegylated Recombinant Human Endostatin in Advanced / Metastatic NSCLC or Other Solid Tumors
Status: UNKNOWN
Conditions: NSCLC|Solid Tumor
Interventions: DRUG: Pegylated Recombinant Human Endostatin（PEG-ENDO）
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HBM9161 on Moderate to Severe Thyroid Eye Disease
Status: UNKNOWN
Conditions: Thyroid Ophthalmopathy
Interventions: DRUG: HBM9161 680 mg qw by q2w from week 13|DRUG: Placebo|DRUG: HBM9161 680 mg qw by q2w from week 7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Topical Formulation for the Treatment and Prevention of Raynaud's Phenomenon Symptoms
Status: UNKNOWN
Conditions: Raynaud Disease
Interventions: DRUG: 0.9% nitroglycerin in TAM cream|DRUG: vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|End Stage Liver Disease
Interventions: OTHER: UC-MSC transplantation|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carotenoid Absorption and Metabolism From Green-leafy Vegetable Matrices
Status: TERMINATED
Conditions: Ileostomy; Functional Disturbance|Healthy
Interventions: DIETARY_SUPPLEMENT: Spinach - Whole leaf (10 mg lutein)|DIETARY_SUPPLEMENT: Spinach - Minced (10 mg/lutein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I/II Multicenter, Open-Label Study of Lu-177-DOTAGA-IAC, for the Treatment of Angiogenic Breast Cancer Patients.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Stage IV
Interventions: DRUG: Lutetium-177-DOTAGA-IAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors.
Status: UNKNOWN
Conditions: Stroke|Gait, Hemiplegic|Hemiplegia
Interventions: DEVICE: Treadmill gait training with GaitBetter|OTHER: Treadmill gait training with GaitBetter + Standard of care|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Docosahexaenoic Acid (DHA) Supplementation in Patients With X-Linked Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: docosahexaenoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: EMA Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms
Status: TERMINATED
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: EMA prompting for patients|BEHAVIORAL: PDF Reports for therapists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Use of Insulin Glargine to Treat Diabetic Ketoacidosis
Status: COMPLETED
Conditions: Diabetic Ketoacidosis
Interventions: DRUG: glargine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Prednisone in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of Isavuconazole|Pharmacokinetics of Prednisolone
Interventions: DRUG: Isavuconazole|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: EUS-guided Obturation of High Risk Gastric Varices Versus Standard Endoscopic Treatment
Status: UNKNOWN
Conditions: Gastric Varix
Interventions: OTHER: EUS guided injection of gastric varices by CYA|OTHER: Direct endoscopic injection of gastric varices by CYA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Explore the Use of Skin Biopsy as Diagnostic Tool in Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
Status: RECRUITING
Conditions: Anterior Cutaneous Nerve Entrapment Syndrome|Nerve Entrapment Syndrome|Chronic Pain Syndrome|Diagnosis
Interventions: PROCEDURE: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Nutritional Supplementation in Picky Eating Children
Status: COMPLETED
Conditions: Children - Malnutrition
Interventions: DIETARY_SUPPLEMENT: Oral nutritional supplement (List No S691/Z0)|DIETARY_SUPPLEMENT: Oral nutritional supplement|OTHER: Dietary Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in Healthy Children Aged From 24mons-15yrs
Status: NOT_YET_RECRUITING
Conditions: Hepatitis A|Hep A
Interventions: BIOLOGICAL: Boryung Hepatitis A Vaccine Pre-Filled Syringe Inj. 0.5 mL|BIOLOGICAL: HAVRIX 720 Junior 0.5 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Loratadine in Lymphangioleiomyomatosis
Status: UNKNOWN
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: Loratadine|DRUG: Placebo 10mg/day added to rapamycin for 12 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore
Status: WITHDRAWN
Conditions: Dengue Fever
Interventions: DRUG: Celgosivir|DRUG: Modipafant 50mg|DRUG: Placebo|DRUG: Modipafant 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Gemcitabine, and Thalidomide in Patients Undergoing Surgery for Stage II or III Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: gemcitabine hydrochloride|DRUG: thalidomide|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: Interferon γ-1b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT for SSLF vs. ISFF With Conventional Surgical Instruments in Chinese Apical Prolapse Female Patients
Status: RECRUITING
Conditions: Apical Prolapse
Interventions: PROCEDURE: native tissue repair procedures with conventional surgical instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Assessment of Post Thrombotic Syndrome : OPTIMEV Study ( SPOT )
Status: COMPLETED
Conditions: Post Thrombotic Syndrome|Venous Thromboembolism|Cardiovascular Diseases
Interventions: OTHER: Villalta phone score > or = to 5|OTHER: Villalta phone score < 5
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer
Status: COMPLETED
Conditions: Mucositis|Head and Neck Cancer
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Gastric Adenocarcinoma
Interventions: DRUG: Evorpacept (ALX148)|DRUG: Trastuzumab|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Intervention Management
Status: WITHDRAWN
Conditions: Traumatic Brain Injury (TBI)|Attention Deficit Hyperactivity Disorder (ADHD)|Head Injury|Brain Concussion|Head Injuries, Closed
Interventions: BEHAVIORAL: AIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Turmeric and Exercise-Induced Muscle Damage and Oxinflammation
Status: COMPLETED
Conditions: Muscular Injury
Interventions: DIETARY_SUPPLEMENT: Turmeric Strength for Joint|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION