pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer Stage IV
Interventions: DRUG: SB27|DRUG: Keytruda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel/Pemetrexed as 1st Line Treatment in Patients With Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiation Therapy for Abiraterone-Resistant, Oligoprogressive Metastatic Prostate Cancer
Status: RECRUITING
Conditions: Oligoprogressive|Castration-Resistant Prostate Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Efficacy of Serratus Anterior Plan Block and Serratus Posterior Superior Intercostal Plan Block in Breast Surgery
Status: RECRUITING
Conditions: Analgesia
Interventions: DRUG: plane block with %0.25 30 ml bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal Morphine
Status: COMPLETED
Conditions: Post Cesarean Pain Management
Interventions: DRUG: Tramadol hydrochloride|DRUG: Morphine|DRUG: Paracetamol|DRUG: Diclofenac|DRUG: TAB. Percocet (Oxycodone 5MG/Paracetamol 325 MG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study Comparing Modified-release Capsules and Immediate Release Capsules in Fed and Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD1446|DRUG: AZD1446|DRUG: AZD1446|DRUG: AZD1446|DRUG: AZD1446|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Two Color Contact Lenses in Habitual Clear Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lenses with color printing|DEVICE: Phemfilcon A contact lenses with color printing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: This is a Study to Assess the Safety and Immunogenicity of Ixiaro® (IC51) in an Elderly Population
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: IXIARO®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Targeting of UnControlled Hypertension in Emergency Department
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases|Vascular Diseases
Interventions: OTHER: HTN Educational Video|OTHER: Visual Echocardiogram Image Clips|OTHER: Mobile Health and Remote BP monitoring|OTHER: Post-Acute Care HTN Transition consultation (PACHT-c)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Platelet Rich Plasm Versus Hyaluronic Acid Injection in Chronic Painful Shoulder
Status: COMPLETED
Conditions: Chronic Shoulder Pain
Interventions: PROCEDURE: platelet rich plasm|PROCEDURE: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing AlloVax™ to Chemotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head & Neck
Status: WITHDRAWN
Conditions: Squamous Cell Carcinoma Head and Neck
Interventions: BIOLOGICAL: AlloVax™|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beraprost-314d Added-on to Tyvaso® (BEAT)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Beraprost Sodium 314d Modified Release Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Safety and Tolerability of VERU-111 in Men With Advanced Metastatic Castration Resistant Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: VERU-111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Different Aprocitentan Tablet Formulations
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Aprocitentan (Formulation A)|DRUG: Aprocitentan (Formulation B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stereotactical Photodynamic Therapy With 5-aminolevulinic Acid (Gliolan®) in Recurrent Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma Multiforme, Adult
Interventions: DRUG: Stereotactic biopsy followed by stereotactical photodynamic therapy with 5-aminolevulinic acid|PROCEDURE: Stereotactic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
Status: COMPLETED
Conditions: Sleep Disturbance|Mood Disturbance
Interventions: DIETARY_SUPPLEMENT: Lemon balm|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian Tube, and Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: Allopurinol|DRUG: Cyclophosphamide|DRUG: Fludarabine phosphate|RADIATION: total-body irradiation|BIOLOGICAL: Allogeneic natural killer cells|BIOLOGICAL: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of RPSG Intervention for Nurses During the COVID-19
Status: UNKNOWN
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: BEHAVIORAL: RPSG|BEHAVIORAL: AVMBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
Status: COMPLETED
Conditions: Stress|Obesity|Overeating
Interventions: BEHAVIORAL: Nutritional Counseling|BEHAVIORAL: Mindfulness Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: protein expression analysis|OTHER: fluorescence activated cell sorting|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TSC Biosample Repository and Natural History Database
Status: RECRUITING
Conditions: Tuberous Sclerosis|Lymphangioleiomyomatosis
Interventions: PROCEDURE: Phlebotomy|PROCEDURE: Buccal (cheek) swab|GENETIC: Genetic Testing|OTHER: Tissue donation after routine clinical procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Glycaemic Balance on the Ability of Apolipoprotein C1 to Inhibit Cholesteryl Ester Transfer Protein in Type-1 Diabetes Patients
Status: COMPLETED
Conditions: diabète de Type 1
Interventions: BIOLOGICAL: Prise de sang
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trabeculectomy Versus Canaloplasty
Status: COMPLETED
Conditions: Glaucoma|Canaloplasty|Trabeculectomy
Interventions: PROCEDURE: trabeculectomy|PROCEDURE: Canaloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Positional Release Technique for Myofascial Trigger Points of the Upper Trapezius
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: Positional release technique|OTHER: Traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Keloid Scarring: Treatment and Pathophysiology
Status: WITHDRAWN
Conditions: Keloid Scar
Interventions: DRUG: 5- fluorouracil|RADIATION: radiotherapy|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise Therapy vs Relaxation in Allogeneic Stem Cell Transplantation (PETRA)
Status: COMPLETED
Conditions: Allogeneic Stem Cell Transplantation
Interventions: BEHAVIORAL: exercise and relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesia in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation (TF-TAVI)
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Nerve block|PROCEDURE: Local infiltration|PROCEDURE: TAVI|DRUG: Additional intraoperative analgesia|DRUG: Additional postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Non Interventional Study on First Line Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)
Status: COMPLETED
Conditions: BRAF V600E Mutation Positive|Metastatic Colorectal Cancer
Interventions: OTHER: Non Interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Lactobacillus Casei DG (Enterolactis Plus®) in Patient With Irritable Bowel Syndrome: a Pilot Study
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei DG|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Inhaled GSK573719|DRUG: Inhaled GSK573719/vilanterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgery With or Without Combination Chemotherapy in Treating Patients With Stomach Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: leucovorin calcium|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine and Oxaliplatin With Radiation Therapy in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine|DRUG: oxaliplatin|PROCEDURE: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Supramaximal High-Intensity Interval Training in People With COPD
Status: COMPLETED
Conditions: COPD|Healthy Older Adults
Interventions: OTHER: Supramaximal High-Intensity Interval Training at 60% of MPO6|OTHER: Moderate-Intensity Continuous Training|OTHER: Supramaximal High-Intensity Interval Training at 80% of MPO6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Learn About the Study Medicines Called Enzalutamide and Abiraterone in People With Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: Enzalutamide|DRUG: Abiraterone acetate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VeClose Five Year Follow-Up Extension Study
Status: COMPLETED
Conditions: Great Saphenous Vein (GSV) With Venous Reflux Disease
Interventions: DEVICE: VenaSeal SCS|DEVICE: ClosureFast Radiofrequency Ablation (RFA)|DEVICE: Roll-In (VenaSeal SCS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Internet-delivered Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Lamotrigine Tablets 25 mg (2 x 25 mg Tablets) Under Fasting Condition
Status: COMPLETED
Conditions: Fasting State
Interventions: DRUG: Lamotrigine Tablets 25 mg|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validating Ultrasound Biomarkers for Hepatic Sinusoidal Obstruction Syndrome in Pediatric Hematopoietic Cell Transplant Patients
Status: WITHDRAWN
Conditions: Sinusoidal Obstruction Syndrome|Veno Occlusive Disease, Hepatic|Bone Marrow Transplant Complications|Stem Cell Transplant Complications
Interventions: DIAGNOSTIC_TEST: Ultrasound Elastography|DRUG: Contrast Enhanced Ultrasound (CEUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Evaluate the Safety of Intratumoral VCL-IM01 Followed by Electroporation in Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: GENETIC: VCL-IM01 (encoding IL-2) with Electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Surgery,Chemotherapy and Autologous T Cells-Based Immunotherapy for Advanced Gastric Cancer.
Status: UNKNOWN
Conditions: Gastric Cancer.
Interventions: BIOLOGICAL: Autologous T cells-Based Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis Patients
Status: RECRUITING
Conditions: Idiopathic Scoliosis|Postoperative Nausea and Vomiting
Interventions: DRUG: Palonosetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium
Status: COMPLETED
Conditions: Delirium|Agitation
Interventions: DRUG: Dexmedetomidine|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Study of MK-4250 Monotherapy in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus (HIV)-1 Infected Participants (MK-4250-002)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: MK-4250
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Plasma Vitamin C Levels in a Population of Chronic Rheumatism in Immuno-Rheumatology
Status: RECRUITING
Conditions: Lupus or SLE|Spondyloarthritis
Interventions: DIAGNOSTIC_TEST: Evaluation of vitamin C level in plasma|OTHER: Evaluation of quality of life
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: PostTraumatic Stress Disorder
Interventions: DEVICE: GammaCore/electroCore non-invasive VNS device|DEVICE: Sham gammaCore/electroCore|DRUG: O-15 water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of Osmotic Release Oral System (OROS) Hydromorphone in Participants With Cancer Pain
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Osmotic Release Oral System (OROS) hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Glycerine|DRUG: Docusate sodium and sorbitol rectal solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: PROCEDURE: euinsulinemic euglycemic glucose clamp|PROCEDURE: euinsulinemic hyperglycemic glucose clamp|PROCEDURE: Hyperinsulinemic euglycemic glucose clamp|PROCEDURE: Hyperinsulinemic hyperglycemic glucose clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sodium Picosulfate Plus Magnesium Citrate Versus Macrogol 4000 in the Bowel Cleansing Procedure: a Comparison of Efficiency and Compatibility
Status: COMPLETED
Conditions: Laxative Compatibility
Interventions: PROCEDURE: Compatibility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis
Status: RECRUITING
Conditions: Pulmonary TB|Pulmonary Tuberculosis|Drug Sensitive Tuberculosis
Interventions: DRUG: TBAJ-876|DRUG: Pretomanid|DRUG: Linezolid|DRUG: Bedaquiline|DRUG: HRZE|DRUG: HR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Brivaracetam Oral Tablet (10 mg, 50 mg, 75 mg and 100 mg) and Brivaracetam Injection (100 mg) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Brivaracetam 10 mg oral tablet|OTHER: Brivaracetam 50 mg oral tablet|OTHER: Brivaracetam 75 mg oral tablet|OTHER: Brivaracetam 100 mg oral tablet|OTHER: 10 mL of Brivaracetam intravenous bolus injection (10 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors
Status: WITHDRAWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xanthine Oxidase Inhibition in Renal Transplant Recipients
Status: TERMINATED
Conditions: Complications of Renal Transplant
Interventions: DRUG: allopurinol or placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Developing a Psychosexual Educational Partners Program: PEPP A Feasibility Study
Status: COMPLETED
Conditions: Breast Cancer|Gynecologic Cancer
Interventions: BEHAVIORAL: Psychosexual Educational Partner Program (PEPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Tonsillectomy on Longterm Renal Outcome of IgA Nephropathy
Status: SUSPENDED
Conditions: IgA Nephropathy
Interventions: PROCEDURE: tonsillectomy|OTHER: non-tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Artificial Intelligence in Endoscopic Diagnosis of Esophagogastric Junctional Adenocarcinoma：A Single Center, Case-control, Diagnostic Study
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms
Interventions: DIAGNOSTIC_TEST: An Intelligent Endoscopic Diagnosis System Developed and Verified Based on Deep Learning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methadone to Treat Painful Chemotherapy Induced Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: methadone|DRUG: duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform
Status: UNKNOWN
Conditions: Telangiectases|Port Wine Stain
Interventions: DEVICE: IPL Quantum Product manufactured by Luminis Ltd.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-Week Open-Label Study to Investigate the Efficacy and Safety of Brepocitinib in Adults With Skin-Predominant Dermatomyositis
Status: NOT_YET_RECRUITING
Conditions: Dermatomyositis|Dermatomyositis, Adult Type
Interventions: DRUG: Brepocitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glottic Visualization & Ease of Intubation With Different Laryngoscope Blades
Status: COMPLETED
Conditions: Tracheal Intubation Morbidity
Interventions: DEVICE: Macintosh Laryngoscope blade|DEVICE: MacCoy|DEVICE: Miller|DEVICE: TrueView
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure
Status: COMPLETED
Conditions: Normal Contact Lens Wear
Interventions: DRUG: Clear Care|DRUG: ReNu|DRUG: OPTI-FREE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Doppler Ultrasound Assisted Varicocelectomy Improve Sperm Qualities
Status: UNKNOWN
Conditions: Varicocele
Interventions: PROCEDURE: Laparoscopic varicocelectomy|PROCEDURE: Microscopic Subinguinal varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT to Investigate if Prophylactic Antibiotics Prevent Further Episodes of Cellulitis (Erysipelas) of the Leg
Status: COMPLETED
Conditions: Cellulitis/Erysipelas of the Leg
Interventions: DRUG: Penicillin VK|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: melphalan|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Association of Anti-inflammatory and Anti-rheumatic
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Meloxicam and Glucosamine|DRUG: Meloxicam|DRUG: Glucosamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation
Status: UNKNOWN
Conditions: Bradycardia|Hypoxemia
Interventions: DRUG: atropine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Randomized Trial of SLOG vs GC in Locally Advanced or Metastatic Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Neoplasms
Interventions: DRUG: Tegafur|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia
Status: COMPLETED
Conditions: Morbidity|Mortality|Complications|Function
Interventions: DEVICE: Femoral catheter|DEVICE: Epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of NKG2D CAR-T in Treating Patients With Recurrent Glioblastoma
Status: UNKNOWN
Conditions: Recurrent Glioblastoma
Interventions: BIOLOGICAL: NKG2D CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Liposomal Bupivacaine Following Retropubic Suburethral Sling for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: DRUG: liposomal bupivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Humanoid Robot vs Treatment as Usual for Loneliness
Status: UNKNOWN
Conditions: Loneliness|Depression|Stress|Anxiety|Quality of Life
Interventions: BEHAVIORAL: Grace Robot|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Sorafenib|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine
Status: COMPLETED
Conditions: Analgesia|Pain|Systemic Inflammatory Stress Response
Interventions: DRUG: clonidine, levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persistence of Physical Activity in People With Type 2 Diabetes Over Time.
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Physical Activity|Psychological
Interventions: BEHAVIORAL: Intervention Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome (PCOS)
Interventions: DRUG: Flutamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults.
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: S. sonnei 1790GAHB|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Medication Compliance and Smoking Cessation Treatment Outcomes for African American Smokers
Status: COMPLETED
Conditions: Smokers
Interventions: DRUG: Chantix|BEHAVIORAL: Adherence Counseling|BEHAVIORAL: Standard Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Versus Quadratus Lumborum Block for Pediatrics
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Quadratus Lumborum Block|PROCEDURE: Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of PMT Therapy of hPAP
Status: RECRUITING
Conditions: Hereditary Pulmonary Alveolar Proteinosis
Interventions: COMBINATION_PRODUCT: Gene-Corrected Macrophages administered by bronchoscopic instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aquatic-based Explosive Strength Training in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Aquatic-based Plyometric Exercises|OTHER: Standard Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study With Clinical Endpoints Comparing Adapalene and Benzoyl Peroxide Topical Gel 0.1%/2.5% (Actavis Mid-Atlantic LLC) To Epiduo™ (Adapalene and Benzoyl Peroxide) Gel 0.1%/2.5% (Galderma Laboratories, L.P.) in the Treatment of Mild to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: adapalene 0.1% and benzoyl peroxide 2.5% topical gel|DRUG: EPIDUO|DRUG: Placebo (Vehicle Gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Xylitol Toothpaste Effective in Preventing Tooth Decay?
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Xylitol toothpaste|OTHER: Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma
Status: RECRUITING
Conditions: Mesothelioma
Interventions: DRUG: Durvalumab / tremelimumab|DRUG: Platinum cisplatin or carboplatin and pemetrexed chemotherapy plus durvalumab/tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Oxytocin Infusion Following Amniotomy in Nulliparous Women
Status: COMPLETED
Conditions: Delivery Delayed|Mode of Delivery|Post Partum Hemorrhage|Uterine Hyperstimulation
Interventions: OTHER: duration of initiation of oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Behavioural Addictions Occurring During a Dopaminergic Treatment Prescribe Under Parkinson's Disease: Study of the Psychopathological, Neurological, Pharmacokinetic and Genetic Profiles
Status: COMPLETED
Conditions: Parkinson's Disease|Secondary Behavioural Addiction
Interventions: OTHER: questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: ZD1839|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Use of taVNS to Treat Insomnia in Individuals With Breast Cancer (taVNS-insomnia-BC)
Status: RECRUITING
Conditions: Breast Cancer|Insomnia
Interventions: DEVICE: transauricular Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Microstructure in Nasal Salmon Calcitonin Treated Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopause
Interventions: DRUG: Salmon calcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Choline Supplementation in Children With Fetal Alcohol Spectrum Disorders
Status: COMPLETED
Conditions: Fetal Alcohol Spectrum Disorders|Fetal Alcohol Syndrome|Partial Fetal Alcohol Syndrome|Alcohol-related Neurodevelopmental Disorder|Prenatal Alcohol Exposure
Interventions: DIETARY_SUPPLEMENT: Choline|DIETARY_SUPPLEMENT: placebo supplementation consisting of vegetable glycerin (50% by volume) and deionized water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Diabetes Patient Takes Responsibility
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Patient Reported Outcome|Health Care Economics and Organizations
Interventions: OTHER: Out-patient clinic on demand (patient-initiated)|OTHER: Scheduled out-patient clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma
Status: COMPLETED
Conditions: Uncontrolled Asthma
Interventions: BIOLOGICAL: Experimental: Tralokinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of ENV8058 (TAK-058) in Healthy Participants
Status: COMPLETED
Conditions: Dose Finding Study
Interventions: DRUG: TAK-058 (ENV8058)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL
Status: TERMINATED
Conditions: Relapsed T-Cell Acute Lymphoblastic Leukemia|Relapsed T-Cell Lymphoblastic Lymphoma
Interventions: DRUG: Nelarabine|DRUG: Etoposide|DRUG: Cyclophosphamide|DRUG: Methotrexate|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients
Status: COMPLETED
Conditions: Heart Failure With Normal Ejection Fraction|Obesity
Interventions: BEHAVIORAL: Increasing daily unsaturated fatty acid consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Uremic Pruritus With PA101B
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: PA101B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors
Status: COMPLETED
Conditions: Gastroscopy Time|Early Gastric Cancer|Detection Rate
Interventions: OTHER: Set the minimum time of gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of GSK2646264
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: GSK2646264 0.5% topical cream|DRUG: GSK2646264 1% topical cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silicone Arthroplasty vs. Arthrodesis in the Distal Interphalangeal Joint
Status: TERMINATED
Conditions: Finger Joint|Arthroplasty|Replacement
Interventions: PROCEDURE: silicone arthroplasty|PROCEDURE: arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cervicothoracic Manipulative Treatment in Unilateral Shoulder Impingement Syndrome: A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Shoulder Pain|Manual Theapy|Exercises Therapy
Interventions: OTHER: Manipulative Therapy Techniques|OTHER: Home Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Procalcitonin in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Procalcitonin|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: procalcitonin-guided antibiotic therapy|DRUG: guideline-guided antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Formulation Screening Study of Dalcetrapib and Atorvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: atorvastatin|DRUG: dalcetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Population Pharmacokinetics of Vancomycin, Meropenem, Milrinone, Dexmedetomidine and Fentanyl in Pediatric Patients During Extracorporeal Membrane Oxygenation
Status: UNKNOWN
Conditions: Pediatric Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis
Status: WITHDRAWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Gerilimzumab|DRUG: Methotrexate|DRUG: Folic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Two Doses of ABX464 in Participants With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ABX464 50mg|DRUG: Matching Placebo|DRUG: ABX464 100mg|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laboratory Study Using Samples From Patients With Non-Small Cell Lung Cancer Treated on Clinical Trial CASE-2507
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: BIOLOGICAL: EHM implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertriglyceridemia
Interventions: DRUG: Omega-3 fatty acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PX-866 and Vemurafenib in Patients With Advanced Melanoma
Status: TERMINATED
Conditions: Advanced BRAF-mutant Cancers
Interventions: DRUG: PX-866|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertension Management in Young Adults Personalised by Echocardiography and Clinical Outcome.
Status: RECRUITING
Conditions: Hypertension
Interventions: DIAGNOSTIC_TEST: Echocardiography scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Magrolimab|DRUG: Pembrolizumab|DRUG: Docetaxel|DRUG: 5-FU|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Ressonance Imaging of Temporomandibular Joint
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction
Interventions: OTHER: Intervention Group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph I Dasatinib + Erlotinib in Recurrent MG
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Erlotinib and Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized RSA Study Comparing HXLPE to Conventional Polyethylene in Cemented Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Arthroplasty Complications
Interventions: PROCEDURE: Device: Randomization between prosthetic components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: treatment with focal HIFU|BIOLOGICAL: PSA dosage|DEVICE: MRI|OTHER: Questionnaires|PROCEDURE: Prostatic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Leflunomide|DRUG: Hydroxychloroquine|DRUG: Prednisolone|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SNIFF - 3-Week Aptar CPS Device
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Impairment|Alzheimer Disease, Early Onset
Interventions: DRUG: Insulin (Humulin® R U-100)|DRUG: Placebo|DEVICE: Aptar Pharma CPS Intranasal Delivery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT