pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage
Status: TERMINATED
Conditions: Retinoblastoma
Interventions: DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients
Status: COMPLETED
Conditions: Leber Hereditary Optic Neuropathy
Interventions: GENETIC: GS010
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity and Immunogenicity of Heat-stable Rotavirus Vaccine (HSRV) in Adults and Infants
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: Heat Stable Rotavirus (HSRV) Vaccine|BIOLOGICAL: Placebo for Heatstable Rotavirus vaccine|BIOLOGICAL: RotaTeq®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-guided Axillary Versus Conventional Cephalic Venous Access for Implantation of Cardiac Devices
Status: COMPLETED
Conditions: Pacemaker|Implantable Cardioverter-defibrillator
Interventions: DEVICE: Ultrasound-guided axillary venous access|DEVICE: Cephalic venous access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICU
Status: NOT_YET_RECRUITING
Conditions: Pre-Eclampsia; Complicating Pregnancy|Pre-eclampsia Aggravated
Interventions: DRUG: Glyceryl trinitrate vs phentolamine for prophylaxis against renal impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment.
Status: COMPLETED
Conditions: Recurrent Classic Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Treatment With Anti-Coronavirus Immunoglobulin
Status: RECRUITING
Conditions: COVID|SARS-CoV2 Infection|Covid19
Interventions: BIOLOGICAL: Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: fNIRS Neurofeedback in Highly Impulsive Participants With ROI Regions DLPFC and IFG
Status: COMPLETED
Conditions: Impulsivity
Interventions: DEVICE: fNIRS-Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Active Versus Passive Methods in Chronic Venous Insufficiency
Status: COMPLETED
Conditions: Chronic Venous Insufficiency
Interventions: OTHER: Exercise Training|OTHER: Massage|OTHER: Neuromuscular Electrical Stimulation|OTHER: Compression Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Attributable Etiology and Modifiable Stroke Risk Factors in Patients With Covert Brain Infarctions
Status: RECRUITING
Conditions: Silent Stroke|Silent Cerebral Infarct|Covert Brain Infarct|Covert Brain Infarction|Lacune|Silent Brain Infarction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancing Attention and Wellbeing Using Digital Therapeutics
Status: RECRUITING
Conditions: Aging|MCI|Cognitive Decline
Interventions: BEHAVIORAL: MediTrain|BEHAVIORAL: Worder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of MDX-1106 to Treat Patients With Hepatitis C Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MDX1106-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: CRC
Interventions: DRUG: HLX208|DRUG: Cetuximab Injection [Erbitux]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety & Immunogenicity of rLP2086 Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MnB vaccine rLP8026|BIOLOGICAL: MnB vaccine rLP8026|BIOLOGICAL: MnB vaccine rLP8026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Topical Glycerine Sulphate Paste, Hirudoid Cream and Nil Application on Superficial Phlebitis
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: Glycerine Magnesium sulphate paste|DRUG: Mucopolysaccharide polysulphate|OTHER: No application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Donafenib in 131I-Refractory Differentiated Thyroid Cancer
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Donafenib 200mg|DRUG: Donafenib 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy for Limited Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasm|Small Cell Carcinoma
Interventions: RADIATION: Hypofractionated Chest Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instant Message-guided Hypertension Management Intervention Among Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Hypertension|Lifestyle Modifications
Interventions: BEHAVIORAL: automated instant message-guided hypertension management intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 3D Evaluation of Clear Aligners Versus Fixed Orthodontic Treatment of Lower Anterior Crowding
Status: COMPLETED
Conditions: Pathological Resorption of External Root
Interventions: DEVICE: U lab aligners|DEVICE: oramco bracket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBP-9414 for the Prevention of Necrotizing Enterocolitis
Status: COMPLETED
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: IBP-9414|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Walking Aid and Locomotion Knowledge in Emergency Rooms (WALKER 1) for Elderly People
Status: RECRUITING
Conditions: Mobility Limitation
Interventions: DEVICE: Walking aid|OTHER: Telemonitoring|OTHER: Guidance on safe walking and risk of falling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD
Status: TERMINATED
Conditions: Muscular Dystrophy (DMD)
Interventions: DRUG: RO7239361|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of NOSE and Conventional Methods in Laparoscopic Total Colon Surgery
Status: COMPLETED
Conditions: Surgical Incision
Interventions: PROCEDURE: natural orifice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Babaodan on Tumor Recurrence After Curative Resection of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Tumor Recurrence
Interventions: DRUG: Babaodan oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of TH Versus THL in First Line Treatment of HER2-positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Algorithms Based on Host Biomarkers to Manage Febrile Children
Status: COMPLETED
Conditions: Acute Febrile Illness
Interventions: OTHER: Management of febrile children using e-POCT|OTHER: Management of febrile children using ALMANACH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat
Status: COMPLETED
Conditions: Tophaceous Gout
Interventions: DRUG: Lesinurad|DRUG: Lesinurad|DRUG: Placebo|DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib With Trastuzumab Deruxtecan for Previously Treated HER2-Low Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Anlotinib|DRUG: Trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Types of Resin Cements on the Color Stability of Two Different Types of Ceramic Veneers
Status: COMPLETED
Conditions: Color; Change Teeth, Posteruptive
Interventions: OTHER: Livento press veneers luted with dual cured resin cement|OTHER: Livento press veneers luted with light cured resin cement|OTHER: Celtra duo veneers luted with dual cured resin cement|OTHER: Celtra duo veneers luted with light cured resin cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: AIR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Painful and Barometric Dynamic Monitoring in the Aftermath of Foot Surgery Using the Distal Metatarsal Mini-invasive Osteotomy (DMMO) Method
Status: UNKNOWN
Conditions: Distal Metatarsal Mini-invasive Osteotomy (DMMO)
Interventions: OTHER: podobarometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: R-CMOP in Patients With Primary Diffuse Large B-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Mitoxantrone hydrochloride liposome|DRUG: Cyclophosphamide|DRUG: Vincristine/Vindesine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Banded Versus Conventional Laparoscopic Roux-en-Y (GABY)
Status: UNKNOWN
Conditions: Morbid Obesity Requiring Bariatric Surgery
Interventions: PROCEDURE: Conventional laparoscopic Roux-en-Y gastric bypass|PROCEDURE: conventional laparoscopic Roux-en-Y gastric bypass with additional restrictive silastic ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Nilotinib and Adriamycin as Treatment in Liposarcomas and Leiomyosarcomas of Retroperitoneum
Status: UNKNOWN
Conditions: Retroperitoneal Liposarcoma|Retroperitoneal Leiomyosarcoma|Chondrosarcoma
Interventions: DRUG: Nilotinib-adriamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Adolescents/Adults to Evaluate Non-inferiority&Persistence up to 5 Years of GSK Bio MenACWY Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: meningococcal ACWY (vaccine)|BIOLOGICAL: Mencevax™ ACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Combination of Paclitaxel Poliglumex and Alimta for Advanced Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: paclitaxel poliglumex, pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrovastatin for Preventing Atrial Fibrillation Following Open Cardiac Valve Repair
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture First for IC/BPS
Status: NOT_YET_RECRUITING
Conditions: Bladder Pain Syndrome|Interstitial Cystitis
Interventions: OTHER: Acupuncture|BEHAVIORAL: Behavioral management|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Rigid Versus Non-rigid Indirect Anchorage During Canine Retraction: A Split Mouth Randomized Study
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: PROCEDURE: non rigid indirect anchorage connection|PROCEDURE: rigid indirect anchorage connection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Mullerian Hormone as Predictor of Ovarian Responce to Clomiphene Citrate in PCOS
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Clomiphene Citrate|DIAGNOSTIC_TEST: Follicular growth
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Trial to Evaluate the Immunogenicity of an Adjuvanted Influenza Vaccine Among HCP
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza
Interventions: BIOLOGICAL: FLUAD Quadrivalent|BIOLOGICAL: FluQuadri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACTIV-5 / Big Effect Trial (BET-B) for the Treatment of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Lenzilumab|OTHER: Placebo|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilator Settings on Patients With Acute Brain Injury
Status: COMPLETED
Conditions: Acute Brain Injury|Ventilator-Induced Lung Injury|Cerebrovascular Circulation
Interventions: PROCEDURE: Lung protective ventilator settings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioimpedance Spectroscopy in Detecting Lower-Extremity Lymphedema in Patients With Stage I, Stage II, Stage III, or Stage IV Vulvar Cancer Undergoing Surgery and Lymphadenectomy
Status: COMPLETED
Conditions: Lymphedema|Perioperative/Postoperative Complications|Stage IA Vulvar Cancer AJCC v7|Stage IB Vulvar Cancer AJCC v7|Stage II Vulvar Cancer AJCC v7|Stage IIIA Vulvar Cancer AJCC v7|Stage IIIB Vulvar Cancer AJCC v7|Stage IIIC Vulvar Cancer AJCC v7|Stage IVA Vulvar Cancer AJCC v7|Stage IVB Vulvar Cancer AJCC v6 and v7
Interventions: PROCEDURE: Bioelectric Impedance Analysis|PROCEDURE: Lymphadenectomy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multimodal Brain Imaging of Methylphenidate in Children and Adolescents With ADHD
Status: WITHDRAWN
Conditions: ADHD
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Bilateral Deep Brain Stimulation to the Globus Pallidus Internum in Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: PROCEDURE: Bilateral GPi Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Video Messages for Smoking Cessation Campaign
Status: WITHDRAWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Developing, Evaluating and Testing Video Messages for a Smoking Cessation Campaign|BEHAVIORAL: Health Message Framing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Repeat Radiation, Minocycline and Bevacizumab in Patients With Recurrent Glioma
Status: COMPLETED
Conditions: Recurrent Glioma
Interventions: DRUG: Bevacizumab|DRUG: Minocycline|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound-guided Lung Ventilation in Determining the Optimum Inspiratory Pressure in Pediatric Patients
Status: COMPLETED
Conditions: Pediatric Lung Atelectasis
Interventions: PROCEDURE: Increasing the inspiratory pressure if atelectasis detected by US
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Reinforced Education by Wechat and Short Message Service on the Quality of Bowel Preparation
Status: UNKNOWN
Conditions: Bowel Preparation Scale|Adenoma Detection Rate
Interventions: OTHER: short message service based re-education|OTHER: Wechat based re-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Mesenchymal Stem Cell (MSC) Transplantation in MS
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Progressive Relapsing Multiple Sclerosis
Interventions: BIOLOGICAL: Autologous mesenchymal stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Use of Regorafenib (Stivarga®) in Patients With Metastatic Colorectal Cancer (mCRC) After Failure of Standard Therapy
Status: COMPLETED
Conditions: Colorectal Neoplasm
Interventions: DRUG: Regorafenib (Stivarga, BAY 73-4506)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Aspirin in Patients With Chronic Coronary Syndromes Without Revascularization
Status: RECRUITING
Conditions: Stable Angina Pectoris|Coronary Artery Disease|Ischemic Heart Disease
Interventions: DRUG: Aspirin|DRUG: No aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TRC105 for Liver Cancer That Has Not Responded to Sorafenib
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatocellular Cancer|Carcinoma, Hepatocellular
Interventions: DRUG: TRC105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study of BAY1834845 in Healthy Male Subjects and in Patients With Psoriasis
Status: COMPLETED
Conditions: Healthy Volunteers|Psoriasis
Interventions: DRUG: BAY1834845|OTHER: Matching Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial.
Status: RECRUITING
Conditions: Locally Advanced Nasopharyngeal Carcinoma|Envafolimab|Induction Chemotherapy|PD-L1
Interventions: DRUG: Envafolimab Plus Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DOD Regulating Together Intervention
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Emotion Regulation
Interventions: BEHAVIORAL: Regulating Together (RT)|BEHAVIORAL: Achieving Independence and Mastery in School (AIMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibody Response to COVID-19 Vaccines in Liver Disease Patients
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: BIOLOGICAL: BNT162b2|BIOLOGICAL: CoronaVac|BIOLOGICAL: AZD1222
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Digital Outpatient Services
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy|Cancer|Interstitial Lung Disease|Long Term Pain
Interventions: OTHER: Dignio Digital Remote Care intervention group|OTHER: Usual Care Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment CLI Nonrevascularizable Lower Limb With Cell Therapy
Status: COMPLETED
Conditions: Nonrevascularizable Critical Ischemia of the Lower Limbs
Interventions: OTHER: Intramuscular injection of a suspension of adult mesenchymal stem cells derived
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ab Interno Gelatin Microstent With MMC vs. Trabeculectomy With MMC: 3 Year Retrospective Cohort Analysis
Status: COMPLETED
Conditions: Filtering Surgery|Trabeculectomy
Interventions: DEVICE: Ab interno gelatin microstent|PROCEDURE: Trabeculectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium
Status: NOT_YET_RECRUITING
Conditions: Older Patients|Nasal Administration|Dexmedetomidine|Esketamine|General Anesthesia|Emergence Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Esketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Aerobic Exercise in Patients With Ankylosing Spondylitis
Status: RECRUITING
Conditions: Ankylosing Spondylitis|Aerobic Exercise|Disease Activity
Interventions: DEVICE: Aerobic exercises with cycling ergometry|OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastoma
Status: TERMINATED
Conditions: Grade IV Astrocytoma|Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: folinic acid at pharmacological dose is the escalated drug|RADIATION: High voltage radiation therapy (linear accelerator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Midazolam Additive to Local Anesthetic in Peribulbar Block
Status: COMPLETED
Conditions: Postoperative Pain|Cataract|Local Anaesthetic Complication|Midazolam
Interventions: PROCEDURE: Peribulbar block (control)|PROCEDURE: Peribulbar block(M1)|PROCEDURE: Peribulbar block(M2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Status: RECRUITING
Conditions: Hemorrhoids|Anal Fissure and Fistula|Perianal Abscess|Perianal Fistula|Pilonidal Sinus|Perianal Skin Tags
Interventions: OTHER: Ultrasound guided Pudendal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TOPIT; Trough Level Optimized Pediatric Inflammatory Bowel Disease Therapy: A Multicenter Study Comparing Effectiveness of Trough Level Optimized Infliximab Maintenance Therapy With Standard Dosing Regimen of Pediatric Patients With Crohn's Disease
Status: UNKNOWN
Conditions: Pediatric Crohns Disease
Interventions: DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Two Berry Extracts on Cognition and Mood in Adults Aged 40 to 60
Status: COMPLETED
Conditions: Ageing
Interventions: DIETARY_SUPPLEMENT: Berry drink|DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Powdered berry drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 Diabetes
Status: TERMINATED
Conditions: Renal Insufficiency, Chronic|Diabetes Mellitus, Type 2
Interventions: DRUG: Bardoxolone Methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Vibostolimab|BIOLOGICAL: Gebasaxturev|BIOLOGICAL: MK-4830|BIOLOGICAL: Favezelimab + Pembrolizumab|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)
Status: COMPLETED
Conditions: Cachexia|Non-Small Cell Lung Cancer
Interventions: DRUG: Anamorelin HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Teriparatide (FORTEO) to Treat Adults With Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Teriparatide (FORTEO)|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: FT516 and IL2 With Enoblituzumab for Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Adenocarcinoma|Primary Peritoneal Cavity Cancer
Interventions: DRUG: IP FT516|DRUG: Enoblituzumab|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate How Safe and Effective Solifenacin Solution is in Treating Children/Adolescents With Symptoms of Overactive Bladder (OAB) Who Completed Study 905-CL-076
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Solifenacin succinate suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Cord Blood Transplant Recipient|Myelodysplastic Syndrome|Myeloproliferative Neoplasm
Interventions: BIOLOGICAL: Recombinant Interleukin-7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of the Type of Reconstruction Methods on Diabetes Following Laparoscopic Distal Gastrectomy in Patients With Gastric Cancer and Type 2 Diabetes
Status: COMPLETED
Conditions: Stomach Neoplasms|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: conventional BI|PROCEDURE: long-limb BII|PROCEDURE: long-limb RY group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MK0928 for Insomnia in Adults (0928-003)(COMPLETED)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: MK0928, gaboxadol / Duration of Treatment - 1 year|DRUG: Comparator: placebo / Duration of Treatment -1 year
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Erlotinib and Dovitinib (TKI258) in Advanced Non-small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC), Recurrent|Non-small Cell Lung Cancer (NSCLC), Stage IV
Interventions: DRUG: Erlotinib hydrochloride|DRUG: Dovitinib lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis
Status: TERMINATED
Conditions: Brain Metastases
Interventions: DRUG: encorafenib|DRUG: binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAST Trial: Multi-modal Analgesic Strategies in Trauma
Status: COMPLETED
Conditions: Nonspecific Pain Post Traumatic Injury
Interventions: DRUG: Acetaminophen IV/PO|DRUG: Acetaminophen PO|DRUG: Ketorolac|DRUG: Celebrex|DRUG: Naproxen|DRUG: Tramadol|DRUG: Pregabalin|DRUG: Gabapentin|DRUG: Lidocaine|DRUG: Opioids|DRUG: Regional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Discharge Communication in the Emergency Department Through Information Structuring
Status: COMPLETED
Conditions: Information Structuring Skills|Empathy Skills
Interventions: BEHAVIORAL: Communication skills training "empathy skills"|BEHAVIORAL: Communication skills training "information structuring skills"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rituximab and Lenalidomide vs Rituximab Alone as Maintenance After R-chemoterapy for Relapsed/Refractory FL Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Follicular
Interventions: DRUG: R2-MANT|DRUG: R-MANT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Green Light and Transcranial Direct Current Stimulation in Migraine Patients
Status: RECRUITING
Conditions: Migraine
Interventions: DEVICE: Transcranial direct current stimulation|DEVICE: Sham transcranial direct current stimulation|DEVICE: Green light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Home Midwifery Care Given to Pregnant Women Diagnosed With Gestational Diabetes on Attitudes and Self-Care
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Pregnancy, High Risk
Interventions: OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity
Status: COMPLETED
Conditions: Pediatric Obesity|Nutrition Disorders|Overnutrition, Child|Obesity
Interventions: BEHAVIORAL: Meal Kit Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Aktiia SA PulseWatch OBPM Device at the Wrist Against Invasive Blood Pressure Measurements
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DEVICE: Aktiia OBPM PulseWatch wrist device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Safety and Effects of Cells Injected Intravitreal in Dry Macular Degeneration
Status: WITHDRAWN
Conditions: Dry Macular Degeneration
Interventions: BIOLOGICAL: Adipose Derived Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Large Diameter GORE EXCLUDER® AAA Endoprosthesis in Abdominal Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: 31 mm GORE EXCLUDER® AAA Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Evaluate the Pharmacokinetics of Ezogabine/Retigabine in Taiwanese Subjects
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: 50mg Ezogabine/retigabine|DRUG: 100mg Ezogabine/retigabine|DRUG: 200mg Ezogabine/retigabine|DRUG: 400mg Ezogabine/retigabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation
Status: COMPLETED
Conditions: Intubation Complication|Tracheal Intubation Morbidity|Anesthesia Intubation Complication|Hypertension|High Blood Pressure|Tachycardia
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bosutinib For Autosomal Dominant Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Bosutinib|DRUG: Bosutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Racism and Discrimination in Schools: Comprehensive Prevention Services
Status: ENROLLING_BY_INVITATION
Conditions: Behavior, Child
Interventions: BEHAVIORAL: CP no REACT|BEHAVIORAL: CP+/No REACT|BEHAVIORAL: CP and REACT|BEHAVIORAL: CP+ and REACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Opt-In Narcotic Treatment Study
Status: COMPLETED
Conditions: Postoperative Pain|Narcotic Use|Analgesia|Endocrine Surgery|Opioid Use|Opioid Abuse
Interventions: BEHAVIORAL: POINT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: High Intensity Resistance and Aerobic Training Among Women With PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: High intensity resistance Exercise Training|OTHER: High intensity aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teen and Young Adult Connections for Support From Multidisciplinary Professionals & Peers
Status: COMPLETED
Conditions: Short Bowel Syndrome|Malabsorption|Malnutrition
Interventions: BEHAVIORAL: mConnect plus mobile connections to multidisciplinary professionals & peers|BEHAVIORAL: iPad use plus one mobile connections to multidisciplinary professionals & peers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Locked Versus Unlocked Set Screws in Intramedullary Fixation of Intertrochanteric Fractures
Status: TERMINATED
Conditions: Hip Fractures
Interventions: DEVICE: Locked Set Screw|DEVICE: Unlocked Set Screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAC +taVNS in IDM Who Are Poor Oral Feeders
Status: COMPLETED
Conditions: Infant of Diabetic Mother|Oxidative Stress|Vagus Nerve Stimulation|Feeding Disorders
Interventions: COMBINATION_PRODUCT: N acetyl cysteine + vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thoracic Mobilization in Females With Coccydynia
Status: RECRUITING
Conditions: Coccyx Disorder
Interventions: OTHER: Thoracic Sustained Natural Apophyseal Glides|OTHER: Muscle Energy Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirasol Evaluation of Reduction in Infections Trial
Status: RECRUITING
Conditions: Transfusion-Transmitted Infectious Disease
Interventions: BIOLOGICAL: Mirasol-treated Fresh Whole Blood|BIOLOGICAL: Standard Fresh Whole Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs
Status: RECRUITING
Conditions: Immunosuppression
Interventions: DRUG: Tacrolimus Pill|DRUG: Tacrolimus capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Switching HIV-1 Infected Subjects From a Highly Active Anti-Retroviral Treatment (HAART) Regimen Dosed Twice Daily or More Frequently to a Once-Daily Regimen
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: stavudine extended-release, lamivudine, efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Centre Trial of Fresh vs. Frozen-and-Thawed FMT for Recurrent CDI
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Fresh FMT|BIOLOGICAL: Frozen-and-Thawed FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Test for Endometrial Receptivity 24 Hours Before Embryo Transfer
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: Day 3 embryo transfer|OTHER: Day 5 embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics, Safety & Tolerability of Isotopologs of Atazanavir (ATV), With Pharmacokinetic Comparison to Reyataz
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: C-10276|DRUG: C-10276|DRUG: C-10297|DRUG: C-10299|DRUG: C-10297|DRUG: C-10299|DRUG: C-10276|DRUG: Reyataz®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Aromatherapy for Symptom Management
Status: UNKNOWN
Conditions: Nausea, Vomiting and Anxiety Associated With Medical Oncology Patients
Interventions: DRUG: Peppermint and Lavender Essential Oils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Deep Brain Stimulation (DBS) of the Pallidal (GPi) in Patients With Tardive Dystonia
Status: UNKNOWN
Conditions: Dystonia|Movement Disorder
Interventions: PROCEDURE: deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Level Laser Therapy On Exercise Induced Muscle Damage in Wrist Flexors Of Untrained Young Adults
Status: COMPLETED
Conditions: Wrist Injuries
Interventions: OTHER: low level laser therapy|OTHER: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Fibrolamellar Hepatocellular Carcinoma (FLC)
Interventions: DRUG: DNAJB1-PRKACA peptide vaccine|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: Vorolanib|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer.
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Breast Neoplasms|Breast Diseases
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-46 PET/CT and 68Ga-FAPI-46 PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery
Status: COMPLETED
Conditions: Opioid Use, Unspecified
Interventions: OTHER: Educational video|OTHER: Standard of care|DRUG: Ibuprofen|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Short-Term and Long-Term Effects of Ankle Joint Taping and Bandaging on Balance, Proprioception and Vertical Jump Among Volleyball Players With Chronic Ankle Instability
Status: COMPLETED
Conditions: Chronic Ankle Instability
Interventions: OTHER: Taping and Bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered CBT for Anxiety Related to Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma|Anxiety
Interventions: BEHAVIORAL: Exposure-based Internet-CBT|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety and Efficacy of Dental Pulp Mesenchymal Cells in the Treatment of Depression
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: Dental pulp mesenchymal cell injection|DRUG: Dental pulp mesenchymal cell vehicle|DRUG: fluoxetine hydrochloride capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene.
Status: COMPLETED
Conditions: Pulmonary Alveolar Proteinosis|Mutation Ala393Thr of the MARS Gene|mutationSer567Leu of the MARS Gene
Interventions: DRUG: Methionine|DRUG: Vitamin B12, B9, B6, C supplementation|DIAGNOSTIC_TEST: Methionine/homocysteine Dosage|DIAGNOSTIC_TEST: Thoracic CT scan|DIAGNOSTIC_TEST: Abdominal and liver ultrasound.|DIAGNOSTIC_TEST: Brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Prophylactic Epinephrine Solution Injection in Prevention of Delayed Post-sphincterotomy
Status: RECRUITING
Conditions: Bleeding Hemorrhage
Interventions: PROCEDURE: epinephrine solution injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Validation of zEEG, a Wireless EEG Recording System for Pediatric and Adult Patients With Epilepsy
Status: UNKNOWN
Conditions: Epilepsy|EEG With Periodic Abnormalities|EEG With Abnormally Slow Frequencies|EEG; Paroxysms, Occipital, Epilepsy of Childhood|EEG; Spikes, Centrotemporal, Epilepsy of Childhood
Interventions: DEVICE: Electroencephalography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p