pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase I Clinical Trial in Chinese Patients of Advanced and (or) Recurrent Solid Tumor/Lymphoma
Status: UNKNOWN
Conditions: Advanced Solid Tumor|Recurrent Solid Tumor|Lymphoma|Recurrent Lymphocyte Depleted Classical Hodgkin Lymphoma
Interventions: BIOLOGICAL: Geptanolimab Injection 1mg/kg|BIOLOGICAL: Geptanolimab Injection 3mg/kg|BIOLOGICAL: Geptanolimab Injection 10mg/kg|BIOLOGICAL: Geptanolimab Injection 1mg/kg, q2w*6|BIOLOGICAL: Geptanolimab Injection 3mg/kg, q2w*6|BIOLOGICAL: Geptanolimab Injection 10mg/kg, , q2w*6|BIOLOGICAL: Geptanolimab Injection 280mg, q3w|BIOLOGICAL: Geptanolimab Injection 3mg/kg, q2w
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Repetitive Transcranial Magnetic Stimulation to Augment Hypnotic Analgesia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: MagPro TMS system (MagVenture, Denmark)|BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Assess the Efficacy of Cannabigerol in Patients With Active Rheumatoid Arthritis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis|Inflammatory Disease
Interventions: DIETARY_SUPPLEMENT: Cannabigerol (CBG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Sacral Erector Spinae Plane Block in Pediatric Anorectal Surgery
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: Sacral ESP block|PROCEDURE: Caudal block|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia-analgesia Methods and Postoperative Delirium
Status: COMPLETED
Conditions: Elderly|Epidural Anesthesia|General Anesthesia|Major Surgery|Postoperative Delirium
Interventions: PROCEDURE: Combined Epi-GA/PCEA|PROCEDURE: GA/PCIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inhaled NO for the Treatment of Viral Pneumonia in Adults
Status: COMPLETED
Conditions: Viral Pneumonia|Nitric Oxide|Respiratory Disease|Pneumonia, Viral|Inhaled Nitric Oxide|Covid19|SARS-CoV Infection
Interventions: DEVICE: LungFit™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products
Status: COMPLETED
Conditions: Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions: OTHER: Cigarette, NIDA test type with 16.6 mg nicotine|OTHER: Cigarette, NIDA test type with <0.45 mg nicotine|OTHER: Electronic cigarette with 18 mg/ml nicotine|OTHER: Electronic Cigarette with no nicotine|OTHER: Moist snuff|OTHER: Sham Smoking|OTHER: Secondhand cigarette smoke (SHS)|OTHER: Conditioned, filtered air|OTHER: Sham Moist Snuff
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Minocycline on Pain Caused by Nerve Damage
Status: COMPLETED
Conditions: Neuropathic Pain Caused by Lumbar Radicular Pain
Interventions: DRUG: Minocycline|DRUG: placebo|DRUG: Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Allogeneic MSC in Patients With Pulp Necrosis and Chronic Apical Periodontitis
Status: COMPLETED
Conditions: Pulp Necroses|Apical Periodontitis
Interventions: BIOLOGICAL: Allogenic transplant of BM-MSC in a root canal from patients with immature apexes and pulpar necrosis and apical periodontitis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Empagliflozin in Reducing Oxidative Stress After Kidney Transplantation
Status: RECRUITING
Conditions: Kidney Transplant; Complications
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars.
Status: UNKNOWN
Conditions: Pulpitis - Irreversible
Interventions: DEVICE: Low Level Laser - Pulse|DEVICE: Low Level Laser - continuous|DEVICE: Low Level Laser - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Structurally Reorganizing Motor Cortex in Stroke Patients Through Hebbian-type Stimulation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Assessment of Gender diVersity In Primary Angioplasty. The OCTAVIA Trial
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nurse-Led Heart Failure Care Transition Intervention for African Americans: The Navigator Program
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Heart Failure Self Care Support|OTHER: Usual heart failure care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Universally Delivered Interventions for Young People
Status: NOT_YET_RECRUITING
Conditions: Distress, Emotional
Interventions: BEHAVIORAL: Behavioral Activation - single session intervention (BA-SSI)|BEHAVIORAL: 4-session Mindset intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy Plus Nephroureterectomy for Locally Advanced Upper Tract Transitional Cell Cancer
Status: WITHDRAWN
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: Gemcitabine and cisplatin|OTHER: Retrospective comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Virtual Reality on Pre-procedural anxieTy Prior to Heart cathEterIzAtion - VR-THEIA
Status: ACTIVE_NOT_RECRUITING
Conditions: Preprocedure Anxiety
Interventions: BEHAVIORAL: Virtual reality experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Suitability of Supplementing Early MIP Surgery (MIPS) of ICH With Pioglitazone
Status: RECRUITING
Conditions: Intracerebral Haemorrhage, Intraventricular
Interventions: DRUG: Pioglitazone 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for Enrollment Into Clinical Research Studies of Neratinib
Status: TERMINATED
Conditions: Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer|Metastatic Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Almac HER-Seq Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Utilization of Hepatitis C Positive Kidneys in Negative Recipients
Status: COMPLETED
Conditions: Kidney Transplant|Hepatitis C|HCV
Interventions: DRUG: Sofosbuvir / Velpatasvir Oral Tablet [Epclusa]|DRUG: Glecaprevir/Pibrentasvir 100 MG-40 MG Oral Tablet [MAVYRET]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Neurofeedback Training and Pain Management in Post-operative Shoulder Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Pain, Shoulder|Post Operative Pain
Interventions: DEVICE: Neurofeedback training|DEVICE: Sham-neurofeedback training|BEHAVIORAL: Pain management protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Psychologically Informed Education in Adolescents With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome
Interventions: OTHER: Psychologically Informed Education Video|OTHER: Anatomy Education Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Transcranial Theta-burst Stimulation and Transcranial Direct Current Stimulation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: cTBS|DEVICE: cathodal tDCS|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fluoroscopic Guided Atlantoaxial Joint Injection on Head and Neck Pain and Sleep Quality in RA Patients
Status: UNKNOWN
Conditions: Pain, Head|Sleep Disturbance
Interventions: DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft
Status: TERMINATED
Conditions: Anal Fistula|Crohn's Disease
Interventions: DEVICE: Surgisis Biodesign Anal Fistula Plug (SurgiSIS AFP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: PRM-151 (Zinpentraxin Alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Safety, Tolerability and Pharmacokinetics of Multiple Doses of BI-CON-02 in Patients With HER2-positive Metastatic Breast Cancer, Previously Treated With Trastuzumab
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: BI-CON-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perampanel Titration and Cognitive Effects
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Perampanel 1 week titration|DRUG: Perampanel 2 week titration|DRUG: Perampanel 4mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Inhaled Iloprost Effects Using the Breelib Nebulizer, on Clinical Outcomes and Physical Activity of Patients With Advanced Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Iloprost (Ventavis, BAYQ6256)|DEVICE: Breelib nebulizer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metronomic Chemotherapy Based on Adaptative Bio-mathematical Model of Oral Vinorelbine in Patients With NSCLC or MPM
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)|Malignant Pleural Mesothelioma (MPM)
Interventions: DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC
Status: RECRUITING
Conditions: Neuroendocrine Neoplasm
Interventions: DRUG: Sintilimab|DRUG: IBI310|DRUG: Surufatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliation Dysphagia Cancer Oesophagus Stent+Brachytherapy Versus Brachytherapy Only
Status: TERMINATED
Conditions: Esophageal Neoplasm
Interventions: PROCEDURE: Stent insertion|RADIATION: Brachytherapy|RADIATION: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: NBP606|BIOLOGICAL: Prodiax-23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anticoagulation Management in Complex Cardiac Surgery
Status: COMPLETED
Conditions: Extracorporeal Circulation
Interventions: OTHER: Activated Clotting Time measurements combined with heparin concentration monitoring|OTHER: Activated Clotting Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Panitumumab Combined With Docetaxel and Cisplatin as a First-line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Status: UNKNOWN
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: panitumumab + docetaxel + cisplatino
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apnea Hypopnea Index Severity Versus Head Position During Sleep
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Sleep Hypopnea|Sleep Apnea|Sleep Apnea, Obstructive|Snoring
Interventions: DEVICE: Dual-axis inclinometer attached to the subject's forehead with tape
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PF-06651600 for the Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: PF-06651600 Induction Dose|DRUG: PF-06651600 Maintenance Dose #1|DRUG: PF-06651600 Maintenance Dose #2|DRUG: PF-06651600 Maintenance Dose #3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Adenosine A2B Receptor Antagonist PBF-1129|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An ACT-enhanced Weight Management and Fitness Program for Navy Personnel
Status: UNKNOWN
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: ACT Enhanced ShipShape|BEHAVIORAL: Standard ShipShape (SS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alkagin Paste in the Prevention of Radiation Dermatitis
Status: TERMINATED
Conditions: Anus Neoplasms|Rectal Neoplasms|Urogenital Neoplasms
Interventions: OTHER: Aveeno cream|OTHER: Alkagin paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Empagliflozin Kinetics on Renal Glucose Reabsorption in Patients With Type II Diabetes and Healthy Controls
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: Empagliflozin|DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetic Comparability of Guselkumab (CNTO1959) When Delivered by 2 Different Devices and as 2 Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Guselkumab (lyophilized formulation)|DRUG: Guselkumab (liquid formulation with PFS-U)|DRUG: Guselkumab (liquid formulation with PFS FID)|DRUG: Guselkumab (liquid formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab in Combination With Capecitabine and Oxaliplatin(XELOX) in Patients With Advanced Gastric Cancer(AGC): Her+XELOX
Status: COMPLETED
Conditions: Metastatic or Recurrent Gastric Adenocarcinoma|Her-2 Positive Gastric Cancer
Interventions: DRUG: Herceptin+XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diffused Ylang-Ylang Essential Oil Amongst Older Persons With Dementia
Status: COMPLETED
Conditions: Dementia|Behavioral and Psychiatric Symptoms of Dementia
Interventions: OTHER: Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Balloon Dilation of the Eustachian Tube in Eustachian Tube Dilatory Dysfunction
Status: RECRUITING
Conditions: Eustachian Tube Dysfunction|Barotitis
Interventions: DEVICE: Balloon dilation of eustachian tube (Stryker XprESS LoProfile ENT dilation system)|OTHER: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of AZD2281 Given in Combination With Paclitaxel in Metastatic Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Triple Negative Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: AZD2281|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Kenya
Status: COMPLETED
Conditions: Malaria|Febrile Illness
Interventions: OTHER: Conditional artemisinin combination therapy subsidy|OTHER: Testing incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Risk and Prevention Study: Evaluation of the Efficacy of n-3 PUFA in Subjects at High Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: N-3 Polyunsaturated Fatty Acids|DRUG: Placebo: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide Acetate|DRUG: Docetaxel|DRUG: Bicalutamide|RADIATION: Radiation|DRUG: Abiraterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT KS-SA Versur KS-BA in Diabetic Patients
Status: NOT_YET_RECRUITING
Conditions: Dental Implant|Diabetes
Interventions: DEVICE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Recombinant Anti-EGFr Antibody in Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Recombinant Anti-EGFr Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aquablation vs. Holmium Laser Enucleation of the Prostate in the Treatment of Benign Prostatic Hyperplasia in Medium to Large Size Prostates
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: PROCEDURE: Aquablation|PROCEDURE: HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypnotic Suggestion After Acquired Brain Injury or Concussion
Status: COMPLETED
Conditions: Acquired Brain Injury|Concussion, Brain
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: Mindfulness-based stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural
Status: TERMINATED
Conditions: Shivering|Labor|Cesarean Delivery
Interventions: DEVICE: Sham bracelet|DEVICE: Acupressure bracelet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Meat-Borne Carcinogens and Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: RADIATION: MeIQx|PROCEDURE: Pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Cariprazine (RGH-188) in the Acute Exacerbation of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Cariprazine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: fondaparinux background and standard dose UFH|DRUG: Fondaparinux background and low dose heparin|DRUG: Open label fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a New Candidate Vaccine Against Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Ad6NSmut; AdCh3NSmut|BIOLOGICAL: Ad6NSmut; AdCh3NSmut|BIOLOGICAL: Ad6NSmut; AdCh3NSmut|BIOLOGICAL: AdCh3NSmut; Ad6NSmut|BIOLOGICAL: AdCh3NSmut; Ad6NSmut|BIOLOGICAL: AdCh3NSmut; Ad6NSmut|BIOLOGICAL: Ad6NSmut; AdCh3NSmut|BIOLOGICAL: AdCh3NSmut; Ad6NSmut|BIOLOGICAL: AdCh3NSmut; Ad6NSmut
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Vomiting in Children - Is Dextrose an Effective Prophylactic Anti-emetic?
Status: COMPLETED
Conditions: Postoperative Vomiting
Interventions: DRUG: Dextrose (D5NS)|DRUG: Ondansetron (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single-blind, Dose-ranging Study of Novel Swine Influenza Virus Vaccine in Japanese Pediatric Subjects
Status: COMPLETED
Conditions: Swine-Origin Influenza A H1N1 Virus
Interventions: BIOLOGICAL: Adjuvanted cell-derived, inactivated novel swine origin A/H1N1 monovalent subunit influenza virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Full Thickness Macular Hole and Internal Limiting Membrane Peeling Study
Status: COMPLETED
Conditions: Stage 2 or 3 Full Thickness Macular Hole
Interventions: PROCEDURE: Vitrectomy, post hyaloid detachment and gas injection with or without ILM peel.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
Status: COMPLETED
Conditions: Postoperative Analgesia|Hand Strength|Health Related Quality of Life|Chronic Shoulder Pain|Breast Cancer Female|Surgical Wound Infiltration|Lymph Node Dissection
Interventions: DRUG: Diclofenac Sodium|DRUG: Levobupivacaine bolus analgesia|DRUG: Levobupivacaine PCA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPT-IN: Online Parent Training Intervention for Young Children Diagnosed With Autism Spectrum Disorder
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: OPT-IN|OTHER: Psychoeducational control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Protocol of BHV-0223 for Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: NO_LONGER_AVAILABLE
Conditions: Amyotrophic Lateral Sclerosis|ALS|Lou Gehrig Disease|Lou Gehrig's Disease|Lou-Gehrigs Disease|Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions: DRUG: Riluzole
Study Type: EXPANDED_ACCESS
Clinical trial: HT-3951 vs. Placebo in Stroke Rehabilitation
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: HT-3951|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer
Status: TERMINATED
Conditions: High-grade Salivary Gland Mucoepidermoid Carcinoma|Recurrent Salivary Gland Cancer|Salivary Gland Acinic Cell Tumor|Salivary Gland Adenocarcinoma|Salivary Gland Poorly Differentiated Carcinoma|Stage IVA Salivary Gland Cancer|Stage IVB Salivary Gland Cancer|Stage IVC Salivary Gland Cancer
Interventions: BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bonipar for Acute and Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: DRUG: Bonipar|DRUG: Diclofenac sodium topical solution 1.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations
Status: COMPLETED
Conditions: Choroideremia|CHM (Choroideremia) Gene Mutations
Interventions: BIOLOGICAL: AAV2-hCHM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fascial Distortion Model With and Without Neuromuscular Inhibition in Patients With Piriformis Syndrome
Status: UNKNOWN
Conditions: Piriformis Syndrome
Interventions: OTHER: Fascial distortion method with neuromuscular inhibition technique|OTHER: Fascial distortion method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
Status: WITHDRAWN
Conditions: Bronchial Epithelial Dysplasia|Chronic Obstructive Pulmonary Disease|Lung Carcinoma|Stage I Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Tobacco-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bronchial Brush Biopsy|PROCEDURE: Bronchoscopy|DRUG: Iloprost|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Prospective Risk Factor Evaluation & Discovery In CTEPH Study
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: PROCEDURE: Post-pulmonary embolism follow up protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study : LEVOBUPIVACAINE Versus Placebo
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: chirocaine (Levobupivacaine)|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial
Status: COMPLETED
Conditions: Inflammation|Fibrosis
Interventions: DRUG: Losartan 100mg daily|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation
Status: COMPLETED
Conditions: Iron Deficiency|Anemia|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Iron Supplement (Ferrous Sulfate Dried)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study on Whether Patients Prefer the Spiriva® Respimat® or the Spiriva® Handihaler® for Treating Their Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium Respimat® (T1)|DRUG: Tiotropium Handihaler® (T2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMS-induced Plasticity Improving Cognitive Control in OCD
Status: ACTIVE_NOT_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Drug Resistant Epilepsy|Epilepsy
Interventions: DEVICE: NaviFUS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dairy and Non-dairy Breakfasts on Satiety and Post-meal Glycemia in Healthy Older Adults
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: OTHER: 2% M.F. Milk|OTHER: White Bread|OTHER: Strawberry Jam|OTHER: 31% M.F. Cheddar Cheese|OTHER: 2% M.F. Plain Greek yogurt|OTHER: Soy Beverage|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial to Assess the Safety and Immunogenicity of DNA Priming Administered by the ID Zetajet® With or Without ID Derma Vax™ Electroporation Followed by IM MVA Boosting in Healthy Volunteers in Tanzania and Mozambique
Status: COMPLETED
Conditions: Vaccines|HIV|Safety|Immunogenicity
Interventions: BIOLOGICAL: HIVIS DNA vaccine|DEVICE: Zetajet|DEVICE: Derma Vax Electroporation|BIOLOGICAL: Modified Vaccinia Ankara (MVA-CDMR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study to Assess the Design of Use of REKOVELLE® in Women Undergoing In Vitro Fertilisation or Intracytoplasmic Sperm Injection Procedures in Routine Clinical Practice
Status: COMPLETED
Conditions: Controlled Ovarian Stimulation
Interventions: DRUG: Follitropin Delta
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Interventions: DRUG: Ivosidenib 500mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Doxorubicin|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temodar Plus Tyrosine Kinase Inhibitors for Progressive CNS Disease
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|CNS Progression
Interventions: DRUG: Temozolomide plus Osimertinib|DRUG: Temozolomide plus Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Angiogenesis Agent AG-013736 In Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Skin Neoplasms
Interventions: DRUG: Axitinib [AG-013736]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CDIAG Regimen in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia, Relapsed, Adult
Interventions: DRUG: CDIAG regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry
Status: RECRUITING
Conditions: Mitral Insufficiency|Mitral Stenosis|Mitral Stenosis With Insufficiency|Heart Failure|Bioprosthesis Failure
Interventions: PROCEDURE: Transcatheter mitral valve-in-valve implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TIVA Versus Desfluran Anaesthesia in Patients Undergoing Bariatric Surgery
Status: COMPLETED
Conditions: Total Intravenous Anesthesia|Desflurane|Obesity|Pain, Postoperative|Nausea, Postoperative
Interventions: DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: Active Remote Ischemic Conditioning|DEVICE: Sham Remote Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENDOBARC-S Study: "Endovascular Branched Stent-grafts for Aortic ARCh Pathologies in Spain"
Status: RECRUITING
Conditions: Thoracic Aortic Aneurysm|Thoracic Aortic Dissection|Stent-Graft Endoleak|Stent-Graft Stenosis|Intramural Hematoma|Aortic Diseases|Cardiovascular Diseases|Vascular Diseases
Interventions: DEVICE: Endovascular exclusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Avazzia-University of Texas Southwestern Medical Center-Tennant Biomodulator® PRO Perfusion Study
Status: TERMINATED
Conditions: Perfusion; Complications|Wound; Foot
Interventions: DEVICE: Avazzia Tennant Biomodulator® PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PR-018: An Open-Label, Safety Extension of Study PR-011
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: EUR-1008 (APT-1008)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darbepoetin Alfa (Aranesp) Following Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MS Versus NICE for Colorectal Lesions
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colorectal Polyp
Interventions: OTHER: Modified Sano's classification|OTHER: NICE classification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sativex® for Relieving Persistent Pain in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Pain|Advanced Cancer
Interventions: DRUG: Nabiximols|DRUG: Placebo (GA-0034)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Effect of He/O2 to Medical Air on Pulmonary Function Disease
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|Healthy
Interventions: DEVICE: spirometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Optic-to-Audio Device in a Pediatric Cohort With CLN3-related Conditions or Low Vision
Status: COMPLETED
Conditions: CLN3-related Disorders|Low Vision
Interventions: DEVICE: OrCam MyEye 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Efficacy and Safety of Sandbag Self Walking-MSAT on Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Sandbag motion style acupuncture treatment|PROCEDURE: Korean medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Removal of Emotional Information From Mind
Status: NOT_YET_RECRUITING
Conditions: Neurofeedback|Cognitive Training|Memory, Short-Term|Functional Magnetic Resonance Imaging (fMRI)
Interventions: OTHER: fMRI neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of IBI363 in Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: IBI363|DRUG: IBI363|DRUG: IBI363|DRUG: IBI363|DRUG: IBI363
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite
Status: COMPLETED
Conditions: Anorexia|Cachexia
Interventions: DIETARY_SUPPLEMENT: eicosapentaenoic acid|DRUG: megestrol acetate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doxil® + Melphalan + Velcade (DMV) in Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma|Patient Participation
Interventions: DRUG: Doxil, melphalan, bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
Status: RECRUITING
Conditions: Obesity
Interventions: DEVICE: Bluetooth-enabled glucometer|DEVICE: Bluetooth-enabled scale|DEVICE: Global Positioning System (GPS) Device|DEVICE: Step it Up mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Overactive Bladder Treatment
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: OTHER: Lactobacillus Probiotic Capsule|OTHER: Matching Lactobacillus Probiotic Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine Responses in PIDD Subjects
Status: RECRUITING
Conditions: X-linked Agammaglobulinemia|XLA|Primary Immune Deficiency|CVID|Common Variable Immunodeficiency|Primary Antibody Deficiencies|Secondary Hypogammaglobulinemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Paternalistic Leadership Training Given to Health Managers on Nurses' Motivation, Organizational Commitment, and Performance
Status: COMPLETED
Conditions: Paternalism|Motivation|Organizational Behavior
Interventions: PROCEDURE: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Pathological Gambling With Naltrexone Pharmacotherapy and Brief Intervention
Status: COMPLETED
Conditions: Pathological Gambling
Interventions: DRUG: Naltrexone pharmacotherapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arrhythmia Identification in Syncope Patients: ePatch® Versus 24h Holter
Status: RECRUITING
Conditions: Arrythmia|Syncope
Interventions: DEVICE: ePatch ® Extended Wear Holter (EWH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vertical Soft Tissue Augmentation With CTG vs ADM
Status: RECRUITING
Conditions: Implant Complication
Interventions: PROCEDURE: Vertical soft tissue augmentation|PROCEDURE: Vertical soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Valsartan|DRUG: Hydrochlorothiazide (HCTZ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Study of Intra-articular Injection of Tocilizumab and Compound Betamethasone
Status: UNKNOWN
Conditions: Rheumatoid Arthritis of Knee
Interventions: DRUG: Intra-articular Tocilizumab|DRUG: Intra-articular Compound Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears)
Status: RECRUITING
Conditions: Glaucoma|Corneal Transplantation|Inflammation
Interventions: OTHER: Sampling of tears|OTHER: Sampling of aqueous humor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-label Study to Assess the Pharmacokinetics of NKTR-118 in Patients With Impaired Hepatic Function
Status: COMPLETED
Conditions: Hepatic; Functional Disturbance
Interventions: DRUG: NKTR-118
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Unilateral Approach for Bilateral Decompression of Lumbar Canal Stenosis
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: unilateral laminotomy|PROCEDURE: decompressive laminectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]|RADIATION: Radiation therapy|PROCEDURE: Mesorectal excision|DRUG: bevacizumab [Avastin]|DRUG: 5-fluorouracil|DRUG: leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Combination Regimen of Dexamethasone Ifosfamide Cisplatin Etoposide in Patients With NK/T Cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: IFO, VP-16, DDP, DXM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT