pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
Status: COMPLETED
Conditions: Seizure Disorder, Partial
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective Drugs
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Atorvastatin|DRUG: Captopril|DRUG: L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 2 of 2)
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Placebo|DRUG: Combination Product (sumatriptan succinate/naproxen sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Antibiotic Therapy for Methicillin Resistant Staphylococcus Aureus Infection
Status: TERMINATED
Conditions: Methicillin-Resistant Staphylococcus Aureus
Interventions: DRUG: Beta-Lactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine for Executive Dysfunction in Adults With ADHD: A Pilot Study
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)|Executive Function Deficits (EFD)
Interventions: DRUG: Placebo|DRUG: Memantine Hydrochloride|DRUG: OROS-Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Butyldeoxynojirimycin|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Atheroscleroses
Interventions: DIAGNOSTIC_TEST: CT coronary angiography and non-contrast CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Oral Supplementation With Magnesium to Reduce Febrile Neutropenia
Status: UNKNOWN
Conditions: Febrile Neutropenia
Interventions: DIETARY_SUPPLEMENT: Magnesium Oxide Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Changes in Central Arterial Pressure When Comparing ACOG Hypertensive Urgency Protocols
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Labetalol|DRUG: Hydralazine|DRUG: nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hand and Foot Syndrome With Traditional Chinese Medicine Formula LC09 in Patients Who Are Receiving Capecitabine for Colorectal and/or Breast Cancer
Status: COMPLETED
Conditions: Hand Foot Syndrome
Interventions: DRUG: Traditional Chinese Medicine Formula LC09|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrates In Combination With Hydralazine in cardiorEnal Syndrome (NICHE) Study
Status: UNKNOWN
Conditions: Cardio-Renal Syndrome
Interventions: DRUG: Hydralazine|DRUG: Isosorbide Dinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unplanned Shifting to Online Distance Learning: Nursing Students' Perception and Achievement
Status: COMPLETED
Conditions: Distance Learning-Online Learning|Traditional Classroom-Based Learning|Coronavirus Disease Social Distancing Measures|Nursing Students' Perception and Achievement
Interventions: OTHER: impliminting Online Distance Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PTK787/ZK222584 With Bevacizumab in Patients With Refractory and/or Advanced Malignancies
Status: COMPLETED
Conditions: Refractory Malignancy|Advanced Malignancies
Interventions: DRUG: PTK787/ZK222584 and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periapical Healing in Response to Endodontically Treated Teeth With Different Sealing Cement
Status: ACTIVE_NOT_RECRUITING
Conditions: Apical Periodontitis
Interventions: DRUG: Zinc-Oxide Eugenol Sealer|DRUG: AH-Plus Epoxy Resin Sealer|DRUG: Bio-C Sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Pilot Study to Evaluate the Effect of EVOO on Lipid Parameters
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Low polyphenol concentration extra virgin olive oil (EVOO)|DIETARY_SUPPLEMENT: High polyphenol concentration extra virgin olive oil (EVOO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine
Status: ENROLLING_BY_INVITATION
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: mRNA-1647|OTHER: mRNA-1647
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Digital Literacy Education Given to Postmenopausal Women on Health Literacy and Quality of Life
Status: RECRUITING
Conditions: Postmenopausal Symptoms|Literacy|Quality of Life|Health Literacy|Digitalism
Interventions: BEHAVIORAL: digital literacy education specific to menopause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aerosol Therapy in Obese COPD Patients.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Moderate|Obesity
Interventions: RADIATION: inhalation protocol|DEVICE: High Flow Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Xanthohumol as an Adjuvant Therapy in Critically Ill COVID-19 Patients
Status: SUSPENDED
Conditions: COVID-19 Respiratory Infection
Interventions: BIOLOGICAL: Xanthohumol - prenylated chalcone extracted from female inflorescences of hop cones (Humulus lupus). Hop-RXn™, BioActive-Tech Ltd, Lublin, Poland; http://xanthohumol.com.pl/
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: StandUPTV: Reducing Sedentary Screen Time in Adults
Status: COMPLETED
Conditions: Sedentary Behavior|Screen Time|Physical Activity|Sleep
Interventions: BEHAVIORAL: Device-based feedback, self-monitoring, and education: CORE|BEHAVIORAL: Sedentary Screen Time lockout: LOCKOUT|BEHAVIORAL: Context-based prompts: TEXT|BEHAVIORAL: Earn sedentary screen time through moderate-vigorous physical activity: EARN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Two Ultrasound Technologies for Ultrasound-guided Catheter Placement in Regional Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: eZono - high-quality 2D ultrasound images|DEVICE: standard 2D ultrasound images
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Compare the Pharmacokinetics and Bioequivalence of "BR2008" With "BR2008-1" in Healthy Volunteers
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: BR2008-1 (R)|DRUG: BR2008 (T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|BCR-ABL1 Fusion Protein Expression|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive|Recurrent Acute Lymphoblastic Leukemia|t(9;22)
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Doxorubicin|DRUG: Methotrexate|DRUG: Prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measures to Lower the Stress Response in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Tetralogy of Fallot (TOF)|Ventricular Septal Defects (VSD)|Atrioventricular Septal Defects (AVSD)
Interventions: DRUG: Fentanyl (High Dose)|DRUG: Fentanyl (Low Dose)|DRUG: Fentanyl (Low Dose) + Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Adrenoreceptor Expressions on Inflammatory Pattern in Refractory Cardiogenic Shock Under VA ECMO
Status: COMPLETED
Conditions: Shock, Cardiogenic|Extra-Corporeal-Life-Support ( ECLS)|Autonomic Nervous System Diseases|Inflammation
Interventions: DIAGNOSTIC_TEST: Biological
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Quality of Life in Individuals With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Tremor|Functionality
Interventions: OTHER: Quality of life|OTHER: Upper limb functionality|OTHER: Grip and pinch strength|OTHER: Tremor amplitude|OTHER: Depression and anxiety levels|OTHER: Clinical manifestations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neoadjuvant Treatment of Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Goserelin|DRUG: Letrozole 2.5Mg Tab|DRUG: Epirubicin|DRUG: cyclophosphamide|DRUG: Docetaxel|DRUG: paclitaxel|DRUG: trastuzumab|DRUG: pertuzumab|DRUG: Capecitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compare the Performance of Targeted Biopsy Versus Aspiration Biopsy With a Pipette for the Diagnosis of Endometrial Cancer
Status: WITHDRAWN
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Blind biopsy with a pipette|PROCEDURE: Targeted biopsy using hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Hypertension,Essential|Heart Failure
Interventions: OTHER: Blood presssure reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast Surgery
Status: SUSPENDED
Conditions: Invasive Breast Carcinoma|Stage II Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer
Interventions: PROCEDURE: Biopsy of Breast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Famitinib in Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Cancer Metastatic|Colorectal Cancer Recurrent
Interventions: DRUG: Famitinib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empowering Health: Acute Psychological Effects of an Electromyostimulation-Whole-Body-Workout
Status: UNKNOWN
Conditions: Depression
Interventions: BEHAVIORAL: whole-body-workout|DEVICE: EMS|DEVICE: EMS-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lao Anti-Microbial Prescribing Guidelines Mobile Phone Application (LAMPA)
Status: COMPLETED
Conditions: Infectious Disease
Interventions: DEVICE: Antimicrobial prescribing guideline mobile phone application (MicroGuide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Ad5CMV-p53 gene|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Pelvic Lymphocele by Floseal During Pelvic Lymphadenectomy for Gynecologic Cancer
Status: UNKNOWN
Conditions: Gynecologic Cancer
Interventions: DRUG: Floseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Pharmacological Effects of a Standardized Cannabis Preparation
Status: COMPLETED
Conditions: Cannabis Use|Healthy Subjects
Interventions: DRUG: Cannabis decoction|DRUG: Cannabis oil|DRUG: Vaporized cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Periodontal Microbiota in Systemic Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Scleroderma Systemic
Interventions: OTHER: Subgingival dental plaque sampling for whole metagenome sequencing of the periodontal microbiota
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post-operative Corticosteroid Treatment After Mitral Valve Surgery
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Hydrocortisone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 3-AP and Radiation Therapy in Treating Patients With Stage III Pancreatic Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer AJCC v6 and v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Tolerability of TRI476 (Oxcarbazepine) in Children With Inadequately Controlled Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Onset Seizures
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Phase 2 Study to Determine Lowest Efficacious Dose of Ovestin in Vulvar and Vaginal Atrophy
Status: WITHDRAWN
Conditions: Vaginal Atrophy
Interventions: DRUG: Estriol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Investigating the Intra-subject Variability of Pharmacokinetics and Glucodynamics of BioChaperone Insulin Lispro U-100 Product and U-200 Product in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BioChaperone Lispro U-100|DRUG: BioChaperone Lispro U-200
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Isotonic 1 Repetition Maximum Measurement With Isometric Muscle Strength Testing In Healthy Females
Status: COMPLETED
Conditions: No Condition, Healthy Females
Interventions: OTHER: Strength testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: Propofol|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Relaxing Breathing Before Each Station of an Objective Structured Clinical Examination
Status: NOT_YET_RECRUITING
Conditions: Performance Anxiety|Stress|Coping Skills
Interventions: BEHAVIORAL: Intervention of standardized relaxing breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Investigate the Bronchodilatory Effect of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Placebo|DRUG: NVA237
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Dextromethorphan to Treat Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Dextromethorphan hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Health Benefits of a Nutritional, Chronobiological and Physical Exercise Intervention in Fibromyalgia and Chronic Fatigue Syndrome (SYNCHRONIZE +)
Status: RECRUITING
Conditions: Fibromyalgia|Chronic Fatigue Syndrome
Interventions: OTHER: multicomponent treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of a Vaccine Dendritic Cell-based Pulsed With Autologous Heat-inactivated in HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: DCV3|BIOLOGICAL: DCV3 with PEG-INF|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo with PEG-INF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of AL2846 Capsule Combined With Gemzar Injection in the Treatment of Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: AL2846 capsules|DRUG: Gemzar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Electronic Stimulation in Patients Who Underwent Reconstruction of the Anterior Cruciate Ligament
Status: TERMINATED
Conditions: Knee Injuries
Interventions: DEVICE: stimulation of the quadriceps muscle with Myospare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Dapagliflozin 10 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Dapagliflozin 10 mg tablets|DRUG: Farxiga® 10 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up Study With Keppra XR (Levetiracetam XR) for Partial Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Keppra XR (Levetiracetam XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine in Indian Infants Previously Given a Dose of Hepatitis B Vaccine at Birth
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Whooping Cough|Hepatitis B|Poliomyelitis|Invasive Hib Infections
Interventions: BIOLOGICAL: Hexaxim™: DTaP-IPV-Hep B-PRP~T combined vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Pattern of Streptococcus Pneumoniae Nasopharyngeal Carriage and Antimicrobial Susceptibility in Healthy Children Aged Less Then 5 Years, in the Area of Milan and Surroundings, Lombardy, Italy.
Status: UNKNOWN
Conditions: Streptococcus Pneumoniae Nasopharyngeal Carriage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomechanical and Viscoelastic Properties of Plantar Fascia in Pregnant Women
Status: COMPLETED
Conditions: Pelvic Girdle Pain|Biomechanical and Viscoelastic Properties of Plantar Fascia|Pregnant Woman
Interventions: OTHER: Evaluation of biomechanics and viscoelastic properties of plantar fascia|OTHER: Evaluation of navıcular drop|OTHER: Evaluation of plantar pressure distrubution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zoledronate Early to Hip Fracture Patients - Safe and Effective?
Status: RECRUITING
Conditions: Hip Fractures|Osteoporosis
Interventions: DRUG: Zoledronic Acid 5Mg/Bag 100Ml Inj|DRUG: sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microneedling Plus the Universal Peel For Acne Scarring
Status: COMPLETED
Conditions: Acne Scarring
Interventions: DRUG: Universal Peel|PROCEDURE: Microneedling|DRUG: Post-Microneedling Skin Care|DRUG: Post-Universal Peel Skin Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 2.0g Daily of MAG-EPA on the AA/EPA Ratio and Inflammation Biomarkers in a Healthy Population Aged of 50+.
Status: COMPLETED
Conditions: Inflammation
Interventions: OTHER: Eicosapentaenoic acid monoglycerid (MAG-EPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Systolic Heart Failure|Ventricular Premature Complexes|Ventricular Tachycardia|Cardiac Resynchronization Therapy|Reduced Biventricular Pacing
Interventions: PROCEDURE: Catheter ablation of ventricular arrhythmia|DRUG: Intensified medical therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms
Status: COMPLETED
Conditions: Methamphetamine Dependence in Remission
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Induction Pressure Pain Threshold in Trigger Points of the Proximal Muscles of Gastrocnemius
Status: COMPLETED
Conditions: Myofascial Trigger Point|Gastrocnemius Muscle|Manual Therapy|Pain Threshold
Interventions: OTHER: Myofascial induction in gastrocnemius muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HVNI Versus NIV In Management Of Acute Hypercapnic Respiratory Failure In OHS
Status: NOT_YET_RECRUITING
Conditions: Obesity Hypoventilation Syndrome (OHS)
Interventions: DEVICE: High-Velocity Nasal Insufflation Therapy|DEVICE: Non-Invasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Nausea in HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: Acupuncture|OTHER: Individualized Acup based on TCM diagnosis|OTHER: Sham Acup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in Adults
Status: COMPLETED
Conditions: Antidiarrheals
Interventions: DRUG: Racecadotril Film-Coated Tablet (FCT)|DRUG: Racecadotril Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of pIL-12 Electroporation Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Tavokinogene Telseplasmid (tavo)|DEVICE: OncoSec Medical System (OMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrafamilial Helicobacter Pylori Infection in Hong Kong
Status: NOT_YET_RECRUITING
Conditions: H.Pylori Infection
Interventions: DIAGNOSTIC_TEST: Urea beath test (UBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Intranasal Mupirocin on Rate of Staphylococcus Aureus Surgical Site Infection Following Cesarean Sections
Status: UNKNOWN
Conditions: Surgical Wound Infection|Cesarean Section|Staphylococcus Aureus
Interventions: DRUG: Mupirocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Combination of Red and White Bahman Retrieved of Iranian Traditional Medicine on Semen Parameters in Idiopathic Oligospermic Men
Status: UNKNOWN
Conditions: Infertility, Male
Interventions: DRUG: Bahman capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Leukemia, Lymphocytic, B Cell|B-Cell Lymphoma|B-Cell Leukemia|Acute Lymphoid Leukemia|B-Non Hodgkin Lymphoma|B-NHL|B-All|Acute Lymphoblastic Leukemia|Acute Lymphocytic Leukemia
Interventions: BIOLOGICAL: CD19/CD22 CAR T-Cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination Against Pneumococcal in Naïve Abatacept Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: pneumococcal polysaccharide vaccine|BIOLOGICAL: pneumococcal conjugate vaccine|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: NRX-1074 1 mg|DRUG: Placebo|DRUG: NRX-1074 5 mg|DRUG: NRX-1074 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of H1N1 Monovalent Vaccine (MEDI3414) in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MEDI3414 [Influenza A/H1N1 live attenuated, intranasal]|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Efficacy & Safety Of TNX-1300 To Placebo With UC For Treatment Of Acute Cocaine Intoxication In ED Subjects (CATALYST)
Status: RECRUITING
Conditions: Cocaine Use|Cocaine Intoxication|Cocaine Toxicity|Cocaine Abuse|Cocaine Adverse Reaction
Interventions: DRUG: TNX-1300 (Injection)|DRUG: Placebo (Injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Meal Composition and Alcohol Consumption on Postprandial Glycemic Control in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Mixed meal with different macronutrient composition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the GORE® TBE Device in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta, Zone 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm, Thoracic|Aorta; Lesion
Interventions: DEVICE: GORE® TAG® Thoracic Branch Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of Creatinine-Based Estimates of the Glomerular Filtration Rate Equation
Status: UNKNOWN
Conditions: Renal Function Disorder
Interventions: OTHER: Development of new estimating Glomerular Filtration Rate (eGFR) equation|OTHER: Validation of new estimating Glomerular Filtration Rate (eGFR) equation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Magnetic Stimulation in Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitiligo and the Koebner Phenomenon (Model of Vitiligo Induction and Therapy: a Clinical and Immunological Analysis)
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: topical tacrolimus treatment|DRUG: topical pimecrolimus treatment|DRUG: local mometasone furoate treatment|DRUG: cold cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH
Status: RECRUITING
Conditions: Multiple Myeloma|Amyloidosis|Cryoglobulinemia|Castleman's Disease|Light Chain Deposition Disease|Heavy Chain Deposition Disease|Polyneuropathy Organomegaly Endocrinopathy Monoclonal Gammopathy and Skin Changes|Smoldering Multiple Myeloma|Plasma Cell Leukemia|Monoclonal Gammopathy of Undetermined Significance (MGUS)|Monoclonal Gammopathy of Renal Significance (MGRS)|Monoclonal Gammopathy of Neurological Significance (MGNS)
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC
Status: COMPLETED
Conditions: Locally Advanced or Metastatic and Unresectable HCC
Interventions: DRUG: SHR-1210|DRUG: Apatinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Floxuridine|DEVICE: Tricumed IP2000V infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Individual Cognitive Stimulation on Memory and Executive Function in Older Adults With Alzheimer's Disease
Status: COMPLETED
Conditions: Dementia|Neurocognitive Disorders|Cognitive Impairment|Cognitive Dysfunction|Cognitive Decline
Interventions: BEHAVIORAL: Cognitive stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of Extremely Low Level Magnetic Fields as Adjunctive Treatment for Type II Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Resonator device|DEVICE: Resonator device - sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults
Status: NOT_YET_RECRUITING
Conditions: Gout With Hyperuricemia in Adults
Interventions: DRUG: HR091506 tablets + placebo of febuxostat tablets|DRUG: febuxostat tablets + placebo of HR091506 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Deep Dermal Burn
Status: COMPLETED
Conditions: Burns
Interventions: DEVICE: BCT Antimicrobial Dressing|DRUG: Flamazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women
Status: COMPLETED
Conditions: Diabetes Prevention in Women After GDM Who Are at High-risk
Interventions: DRUG: DAPA/MET XR|DRUG: DAPA|DRUG: MET XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester Abortion
Status: UNKNOWN
Conditions: Second Trimester Abortion
Interventions: DRUG: Mifepristone|DRUG: Placebo|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of Pregnancy
Status: UNKNOWN
Conditions: Gestational Hypertension|Toxemia|Superimposed Preeclampsia|Eclampsia|HELLP Syndrome
Interventions: DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Effect of Lactisole on the Intestinal Glucose Uptake
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: lactisole|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Testing of Adding Nivolumab to Chemotherapy in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: Nivolumab|DRUG: Cisplatin|DRUG: Cetuximab|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cystogastrostomy Versus Endoscopic Cystogastrostomy
Status: COMPLETED
Conditions: Pancreatic Pseudocyst
Interventions: PROCEDURE: Laparoscopic cystogastrostomy|PROCEDURE: Endoscopic cystogastrostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Breast Ca Carboplatin + Paclitaxel With Pertuzumab + Trastuzumab or Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Dexmedetomidine|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Anti-PD-1 AK105 in Patients With Metastatic Squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer Non-small Cell Stage IV|Squamous Cell Lung Cancer
Interventions: BIOLOGICAL: AK105|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) Patients
Status: RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: AHB-137 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PHL Treatment in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: COMBINATION_PRODUCT: Paricalcitol, Hydroxychloroquine, Losartan|OTHER: Neoadjuvant therapy and surgery only (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes of Endoscopic Papillary Balloon Dilation for 8-12mm Bile Duct Stones: a Prospective Study
Status: COMPLETED
Conditions: Endoscopic Papillary Balloon Dilation|Bile Duct Stones|Endoscopic Sphincterotomy|Stone Recurrence
Interventions: PROCEDURE: ERCP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DRUG: Sorafenib and Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib With Methotrexate and Temozolomide for Patients With Newly Diagnosed Primary CNS Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma|PCNSL|Non Hodgkin Lymphoma
Interventions: DRUG: Methotrexate|DRUG: Ibrutinib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEUROFEEDBACK on Event-Related Potential (ERP)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: OTHER: Neurofeedback training|OTHER: Active Sham control|OTHER: Baseline control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: Antipyrine and Benzocaine otic solution|DRUG: Antipyrine Otic Solution|DRUG: Benzocaine Otic Solution|DRUG: Placebo Otic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
Status: RECRUITING
Conditions: Respiratory Insufficiency|Depression|Rehabilitation|Critical Care
Interventions: BEHAVIORAL: Behavioral Activation - Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina
Status: COMPLETED
Conditions: Stable Angina
Interventions: PROCEDURE: Coronary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
Status: COMPLETED
Conditions: Neoplasms|Constipation|Opioid-Related Disorders
Interventions: DRUG: Methylnaltrexone bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficacy and Safety of Highly Purified Urofollitropin in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Highly Purified Urofollitropin|DRUG: Recombinant Human Follitropin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Doses Study of KLS-2031 in Subjects With Neuropathic Pain From Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Neuropathic Pain From Lumbosacral Radiculopathy
Interventions: DRUG: KLS-2031|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.
Status: COMPLETED
Conditions: Ectopic Lipids|Insulin Sensitivity|Aerobic Exercise|Fat Load|Growth Hormone Deficiency
Interventions: DIETARY_SUPPLEMENT: Fat diet|OTHER: 2h standardized aerobic exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bowel Preparation for Colonoscopy in the Elderly
Status: COMPLETED
Conditions: Bowel Preparation|Colonoscopy
Interventions: DRUG: Standard full-volume PEG|DRUG: Split-dose full-volume PEG|DRUG: Split-dose low-volume PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Efficacy and Safety of T2750 and Vismed® in the Treatment of Moderate to Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: T2750|DEVICE: Vismed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabis Oil for Chronic Non-Cancer Pain Treatment
Status: UNKNOWN
Conditions: Chronic Non-cancer Pain
Interventions: DRUG: CBD|DRUG: CBD+THC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Endomicroscopy During TransUrethral Resection for Improving BC Diagnosis and Treatment
Status: COMPLETED
Conditions: Bladder Cancer|CLE
Interventions: DEVICE: Confocal Laser Endomicroscopy (CLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between 5-aminolevulinic Acid Photodynamic Therapy Versus Cryotherapy for Actinic Keratosis Treatment
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 5-ALA Photodynamic Therapy|DRUG: Cryotherapy with liquid nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery
Status: COMPLETED
Conditions: Rhinosinusitis
Interventions: DRUG: Normal saline heated up to 50 °C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Progression to Type-2 Diabetes (APT-2D): A Prospective Cohort Study Expanded From BRITE-SPOT (Bio-bank and Registry for StratIfication and Targeted intErventions in the Spectrum Of Type 2 Diabetes)
Status: UNKNOWN
Conditions: Pre-diabetes|Diabetes
Interventions: PROCEDURE: Not applicable. This is an observational study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sonographic Signs of Gouty Arthritis in a Cohort of Egyptian Patients: a Cross Sectional Multicenter Study
Status: COMPLETED
Conditions: Sonographic Signs of Gouty Arthritis in Diagnosed and Suspected Patients
Interventions: DIAGNOSTIC_TEST: Evaluation of sonographic signs of gouty arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p