pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A 28-day Clinical Study on Facial Skin Rejuvenation
Status: COMPLETED
Conditions: Wrinkle|Skin Laxity|Skin Manifestations|Skin
Interventions: COMBINATION_PRODUCT: Fotona4D Pro® treatment followed by daily use of formulations containing MLYAAT-1002®|COMBINATION_PRODUCT: Fotona4D Pro® treatment followed by daily use of formulations without MLYAAT-1002®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: I-ZIP Ocular Bandage Pivotal Study
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: I-ZIP Ocular Bandage|DEVICE: Oasis 24 Hour Soft Shield Collagen Corneal Shield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Standard of care administration of Endocrine therapy|DRUG: Dose-frequency escalation administration of Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique Versus Active Release Technique on Pain, Cervical Range Of Motion And Functional Disability
Status: COMPLETED
Conditions: Upper Cross Syndrome
Interventions: OTHER: Muscle Energy Technique|OTHER: Active Release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS)
Status: UNKNOWN
Conditions: Dengue Shock Syndrome
Interventions: DRUG: Hypertonic sodium lactate|DRUG: Ringer's lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Viral Load Testing to Enable Streamlined Care and Task Shifting for Chronic HIV Care
Status: COMPLETED
Conditions: Chronic HIV Infection
Interventions: DIAGNOSTIC_TEST: Point-of-care viral load testing|OTHER: Lab-based viral load testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Facial Block for Outpatient Rhinoplasty Analgesia
Status: UNKNOWN
Conditions: Outpatient Rhinoplasty
Interventions: DRUG: Bilateral facial block after general anesthesia before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PREDIN: Pregnancy and Vitamin D Intervention Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitamin D Deficiency|Vitamin D3 Deficiency|Pregnancy Complications
Interventions: DIETARY_SUPPLEMENT: Vitamin D Supplementation 20 µg/day|DIETARY_SUPPLEMENT: Vitamin D Supplementation 40 µg/day|OTHER: Usual Antenatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Ropivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan in Hypertensive Men and Women With Sleep Apnea Before and on Continuous Positive Airway Pressure (CPAP) Treatment
Status: COMPLETED
Conditions: Hypertension|Sleep Apnea
Interventions: DRUG: Losartan|OTHER: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer
Status: RECRUITING
Conditions: Stage III Hepatocellular Carcinoma AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Unresectable Hepatocellular Carcinoma|Unresectable Intrahepatic Cholangiocarcinoma
Interventions: BIOLOGICAL: Atezolizumab|BIOLOGICAL: Bevacizumab|RADIATION: External Beam Radiation Therapy|PROCEDURE: Pheresis|BIOLOGICAL: Pneumococcal 13-valent Conjugate Vaccine|BIOLOGICAL: Therapeutic Autologous Dendritic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Lu AG09222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy Followed by Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed or Refractory AIDS-Related Non-Hodgkin's Lymphoma
Status: WITHDRAWN
Conditions: AIDS-related Lymphoma|Adult Non-Hodgkin's Lymphoma|Anaplastic Large Cell Lymphoma
Interventions: DRUG: cisplatin|DRUG: cytarabine|DRUG: etoposide|DRUG: methylprednisolone|DRUG: rituximab|DRUG: yttrium Y 90 ibritumomab tiuxetan|PROCEDURE: antibody therapy|PROCEDURE: biological therapy|PROCEDURE: chemotherapy|PROCEDURE: monoclonal antibody therapy|PROCEDURE: radiation therapy|PROCEDURE: radioimmunotherapy|PROCEDURE: radioisotope therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviews Based on the Transtheoretic Model on Pregnant Women's Smoking Cessation Behaviors
Status: COMPLETED
Conditions: Smoking Cessation|Smoking, Tobacco
Interventions: BEHAVIORAL: Smoking Cessation Program Based on Transtheoretic Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-Treatment of Highly Suspicious Pigmented Skin Lesions With Interleukin-2
Status: TERMINATED
Conditions: Melanoma (Skin)|Melanoma in Situ
Interventions: BIOLOGICAL: Aldesleukin|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI)
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BIOLOGICAL: Whole blood transfusion|BIOLOGICAL: Blood components transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Primary Percutaneous Coronary Intervention (PPCI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extended Systematic Versus Mri-Assisted pRostate Transperineal Biopsy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: MRI and MRI-guided prostate biopsy|DIAGNOSTIC_TEST: TP-arm Systematic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tapentadol (CG5503)
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Pain
Interventions: DRUG: oxycodone|DRUG: placebo|DRUG: tapentadol (CG5503)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Nalbuphine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility, Usability, and Acceptability of Using the Oculus™ Virtual Reality Gaming Technology in Stroke Survivors for Upper Extremity and Cognitive Rehabilitation
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Oculus VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Apatinib Plus Capecitabine Versus Capecitabine in Maintenance Therapy for Patients With Advanced Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Apatinib|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Botulinum Toxin A Injection Patterns in the Treatment of Blepharospasm
Status: UNKNOWN
Conditions: Blepharospasm
Interventions: PROCEDURE: Botulinum toxin A injection (5 sites: 12.5U)|PROCEDURE: Botulinum toxin A injection (4 sites: 10U)|DRUG: Botulinum toxin A 12.5U|DRUG: Botulinum toxin A 10U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Effectiveness of Cognitive Training
Status: COMPLETED
Conditions: Cognitive Change
Interventions: BEHAVIORAL: True Cognitive Training Program|BEHAVIORAL: Control Cognitive Training Program|BEHAVIORAL: Positive Expectation Induction|BEHAVIORAL: Negative Expectation Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))
Status: RECRUITING
Conditions: Colitis Ulcerative
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Insufflation-Exsufflation in Preventing Post Extubation Respiratory Failure in Patient With Critical Care Neuromyopathy
Status: COMPLETED
Conditions: Acute Respiratory Insufficiency|Respiratory Failure
Interventions: PROCEDURE: MI-E plus manually assisted coughing|PROCEDURE: manually assisted coughing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Window-of-opportunity Study of U3-1402, a HER3-targeting Antibody-drug Conjugate in Operable Breast Cancer According to ERBB3 Expression
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: U3 1402|DRUG: U3 1402
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Side-effect Score (ESS): Development and Evaluation of a New Tool for Patients After Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Vomiting and Nausea|Postoperative Complications|Mental Status Changes Postoperative
Interventions: OTHER: Efficacy Safety Score|OTHER: Verbal Numeric Rating Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trials of Hypertension Prevention (TOHP)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, sodium-restricted (Phase III) diet, sodium-restricted|BEHAVIORAL: diet, reducing (Phase III)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Sex- and Context-dependent Effects of Oxytocin on Social Reward Processing
Status: UNKNOWN
Conditions: Mental Health Wellness 1|Social Behavior|Emotion
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraumbilical Vein Injection of Oxytocin in Routine Practice for Active Management of the Third Stage of Labor
Status: COMPLETED
Conditions: Labor
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-flow Nasal Oxygenation for Open Mouth
Status: TERMINATED
Conditions: Anesthesia, General|Apnea
Interventions: DEVICE: Apnea with high-flow nasal cannula|OTHER: Apnea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dopamine in Orthostatic Tolerance
Status: TERMINATED
Conditions: Postural Tachycardia Syndrome
Interventions: DIETARY_SUPPLEMENT: dietary sodium|DIETARY_SUPPLEMENT: dietary sodium|DIETARY_SUPPLEMENT: dietary sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Misoprostol Labour Induction Study
Status: COMPLETED
Conditions: Induction of Labour|Labour, Induced
Interventions: DRUG: Oral Misoprostol|DRUG: Vaginal Misoprostol|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Surgical Resection|DRUG: Adjuvant Atezolizumab-Bevacizumab Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study)
Status: RECRUITING
Conditions: Lung Cancer, Non-small Cell|EGFR Gene Mutation|EGFR-TKI Resistant Mutation|Primary Resistance|Circulating Tumor DNA
Interventions: OTHER: Genomic profiles detection|OTHER: circulating tumor DNA detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of Threshold Values of Aldosterone in HPLC-MS/MS, of Renin and of the Aldosterone / Renin Ratio for the Diagnosis of Primary Hyperaldosteronism
Status: RECRUITING
Conditions: Hyperaldosteronism; Primary
Interventions: OTHER: Aldosterone in HPLC-MS/MS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Determine the Efficacy of a Laser Device for the Treatment of Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: DEVICE: 1320nm Nd: YAG nonablative laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attenuation of Inflammatory Processes Associated With Alzheimer's Disease After Consumption of Pomace Olive Oil.
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: OTHER: Experimental meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Functional Impact of Adenotonsilectomy
Status: COMPLETED
Conditions: Apnea, Obstructive|Tonsillitis|Tonsillar Hypertrophy|Respiratory Function Impaired|Infections|ENT Disorder
Interventions: PROCEDURE: Adenotonsillectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Escalation Trial of WT1-specific Donor-derived T Cells Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: busulfan|DRUG: melphalan|DRUG: fludarabine|BIOLOGICAL: anti-thymocyte globulin (ATG)|PROCEDURE: a T cell depleted stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Weightbearing in Femoroacetabular Impingement Syndrome Patients
Status: UNKNOWN
Conditions: Femoroacetabular Impingement Syndrome
Interventions: OTHER: Early Weightbearing|OTHER: Protected Weightbearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vertebroplasty and Kyphoplasty in Osteoporotic Vertebral Body Fractures.
Status: UNKNOWN
Conditions: Osteoporotic Fracture of Vertebra
Interventions: PROCEDURE: vertebroplasty|PROCEDURE: kyphoplaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 and Aspirin in Periodontal Regeneration
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: OTHER: Regenerative therapy (omega 3 PUFA plus low dose aspirin)|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Strategies for Resilient Intrinsic Self-Regulation in Extremes (RISE)
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Resilient Intrinsic Self-Regulation Strategies in Extremes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Muscle Structure, Function and Gait in dHMN
Status: COMPLETED
Conditions: Distal Hereditary Motor Neuropathy, Type II|Distal Hereditary Motor Neuropathy, Type V|Distal Hereditary Motor Neuronopathy Type I|Distal Hereditary Motor Neuronopathy Type VI
Interventions: DEVICE: Carbon Fibre Ankle Foot Orthosis|BEHAVIORAL: Exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective, Open, Self-controlled Study of the Effects of Chiglitazar Sodium on Glucose and Lipid Metabolism in Patients With Type 2 Diabetes Mellitus (T2DM)
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: DRUG: Chiglitazar sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Priming for Upper Extremity Hemiparesis in Older Adults
Status: COMPLETED
Conditions: Stroke, Upper Extremity Hemiparesis
Interventions: BEHAVIORAL: priming and task specific training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Dysmotility and Dilatation After Laparoscopic Gastric Banding
Status: COMPLETED
Conditions: Esophageal Motility Disorders
Interventions: PROCEDURE: Laparoscopic surgery|PROCEDURE: gastric banding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Effect of Detecting Common Mental Disorders in Long-term Sickness Absence
Status: COMPLETED
Conditions: Psychiatric Disorders|Common Mental Disorders|Depression|Anxiety|Somatoform Disorder
Interventions: PROCEDURE: psychiatric examination and feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EAT: A Reliable Eating Assessment Technology for Free-living Individuals
Status: NOT_YET_RECRUITING
Conditions: Wearable Electronic Device
Interventions: DEVICE: Blur Obfuscation|DEVICE: Cartoon Obfuscation|DEVICE: Edge Obfuscation|DEVICE: No Obfuscation (raw)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Closed-Loop Insulin in Mothers With Type 1 Diabetes and Baby Feeding Practices
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1 Pre-Existing|Pregnancy Related|Feeding Behavior|Infant Development
Interventions: COMBINATION_PRODUCT: Early auto-mode|COMBINATION_PRODUCT: Delayed auto mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Evaluating the Efficacy and Safety of Pembrolizumab in Combination With Chemotherapy as Neoadjuvant Therapy for Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Sparing Block vs. Peri-Articular Catheters
Status: TERMINATED
Conditions: Knee Joint Arthritis|Knee Joint Arthroplasty
Interventions: PROCEDURE: Motor Sparing Nerve Block|PROCEDURE: Peri-articular Catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Leukocyte Interleukin, Injection for Treatment of Perianal Warts
Status: TERMINATED
Conditions: Perianal Warts
Interventions: BIOLOGICAL: Leukocyte Interleukin, Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hyperbaric Oxygen Brain Injury Treatment Trial
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Hyperbaric oxygen (1.5 ATA, no NBH)|DRUG: Hyperbaric oxygen (2.0 ATA, no NBH)|DRUG: Hyperbaric oxygen (2.5 ATA, no NBH)|DRUG: Hyperbaric oxygen (1.5 ATA + NBH)|DRUG: Hyperbaric oxygen (2.0 ATA + NBH)|DRUG: Hyperbaric oxygen (2.5 ATA + NBH)|DRUG: Normobaric Hyperoxia (NBH)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination of Children Following Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Allogeneic Haematopoietic Stem Cell Transplantation
Interventions: BIOLOGICAL: DTaP-IPV-HBV/Hib combination vaccine, Infanrix hexa|BIOLOGICAL: heptavalent pneumococcal conjugate vaccine, Prevenar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Knee Degenerative Disease|Knee Osteoarthritis
Interventions: OTHER: Autologous bone marrow mesenchymal stem cells (MSV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Activity of P501-AS15 Vaccine as a First-line Treatment for Patients With Hormone-sensitive Prostate Cancer Who Show Rising PSA
Status: COMPLETED
Conditions: Neoplasms, Prostate
Interventions: BIOLOGICAL: P501-AS15 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CDK4/6-inhibitor or Chemotherapy, in Combination With ENDOcrine Therapy, for Advanced Breast Cancer / KENDO
Status: UNKNOWN
Conditions: Hormone Receptor Positive Breast Cancer|Metastatic Breast Cancer|Hormone Receptor Negative Breast Cancer
Interventions: DRUG: concomitant cyclin-dependent Kinase 4/6 (CDK4/6) inhibitor plus endocrine therapy|DRUG: chemotherapy plus endocrine therapy (administered either concomitantly or sequentially)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Milademetan Tosylate|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mental Health Intervention for a Community Program Called the PowerObesity
Status: WITHDRAWN
Conditions: Mental Health Wellness 1|Depression|Anxiety|Sedentary Behavior|Obesity|Poor Nutrition
Interventions: BEHAVIORAL: Mental Health lifestyle intervention|OTHER: Dietitian-led
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Activity of Tiragolumab in Participants With Relapsed or Refractory Multiple Myeloma or With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Multiple Myeloma|Non-Hodgkin Lymphoma|B-Cell Lymphoma
Interventions: DRUG: Tiragolumab|DRUG: Daratumumab/rHuPH20|DRUG: Rituximab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effect of Different Drugs and Infusion Ways on Degree of Postoperative Comfort
Status: COMPLETED
Conditions: Analgesia, Patient-Controlled
Interventions: DRUG: intravenous sufentanil|DRUG: subcutaneous sufentanil|DRUG: intravenous hydromorphone|DRUG: subcutaneous hydromorphone|DRUG: intravenous sufentanil and dexmedetomidine|DRUG: subcutaneous sufentanil and dexmedetomidine|DRUG: intravenous hydromorphone and dexmedetomidine|DRUG: subcutaneous hydromorphone and dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: tisotumab vedotin|DRUG: topotecan|DRUG: vinorelbine|DRUG: gemcitabine|DRUG: irinotecan|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment for COVID-19 in High-Risk Adult Outpatients
Status: TERMINATED
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Ascorbic Acid|DRUG: Hydroxychloroquine Sulfate|DRUG: Azithromycin|DRUG: Folic Acid|DRUG: Lopinavir 200 MG / Ritonavir 50 MG [Kaletra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RESTORE: An RCT to Evaluate the Efficacy of the Revi System
Status: RECRUITING
Conditions: Urinary Urge Incontinence
Interventions: DEVICE: Revi System Treatment|DEVICE: Revi System - Delayed Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients
Status: COMPLETED
Conditions: Liver Transplantation|Kidney Transplantation
Interventions: DRUG: Tacrolimus granules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence
Status: UNKNOWN
Conditions: Methicillin-Resistant Staphylococcus Aureus|Recurrence|Staphylococcal Skin Infections|Antibiotic Resistance
Interventions: DRUG: 2% mupirocin ointment|OTHER: Chlorhexidine wash|BEHAVIORAL: Hygiene protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement
Status: RECRUITING
Conditions: Endogenous Cushing Syndrome|Adrenal Insufficiency|Hypercortisolism
Interventions: DRUG: Osilodrostat
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Abicipar Pegol|DRUG: Ranibizumab|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Rabeprazole sodium|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)|Lymphoma, Non-Hodgkin (NHL)|Acute Myeloid Leukemia (AML)|Multiple Myeloma (MM)
Interventions: DRUG: CAL-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI346#CIBI346Y001#
Status: COMPLETED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: IBI346
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ice, Green Tea and Arnica Montana Application on Post-Operative Intubation Related Sore Throat and Hoarseness
Status: COMPLETED
Conditions: Sore Throat|Hoarseness
Interventions: OTHER: Comparıson
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Sensorimotor Locus of Balance Control in Elderly Gait
Status: COMPLETED
Conditions: Ambulation Difficulty|Gait, Unsteady|Fall|Position Sense Disorders
Interventions: BEHAVIORAL: Optical flow perturbations|BEHAVIORAL: Normal walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome|Posttraumatic Stress Disorder
Interventions: DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury
Status: COMPLETED
Conditions: Osteoarthritis|Arthritis, Rheumatoid|Dyspepsia
Interventions: DRUG: Rabeprazole|DRUG: Rabeprazole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Genetic Disease|Hematologic Diseases|Anemia, Sickle Cell
Interventions: OTHER: Electronic Health Record (EHR) Embedded Individualized Pain Plan (IPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy
Status: RECRUITING
Conditions: Cerebral Palsy|Hypoxic-Ischemic Encephalopathy
Interventions: BEHAVIORAL: Sensorimotor Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Thymic Carcinoma|Thymoma Type B3
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency
Status: COMPLETED
Conditions: Alcoholism|Alcohol Abuse
Interventions: DRUG: Quetiapine fumarate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3209590 in Japanese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3209590|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cemented TrendHip® - Multicenter PMCF Study on Total Indications
Status: ACTIVE_NOT_RECRUITING
Conditions: Coxarthrosis; Primary|Coxarthrosis; Post-Traumatic|Necrosis, Femur Head|Rheumatoid Arthritis|Fractures, Hip|Hip Dysplasia
Interventions: DEVICE: Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF
Status: TERMINATED
Conditions: Persistent Cough in IPF|Chronic Cough|IPF
Interventions: DRUG: RVT-1601|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study for the Treatment of Iris Neovascularization With Macugen
Status: COMPLETED
Conditions: Iris Neovascularization|Diabetic Retinopathy
Interventions: OTHER: Pegaptanib Sodium Injection/Panretinal Photocoagulation|PROCEDURE: Panretinal Photocoagulation (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of a Single Application of Capsaicin 8%Transdermal Delivery System Compared to Placebo in Reducing Pain Intensity in Subjects With Painful Diabetic Peripheral Neuropathy (PDPN)
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy|Pain
Interventions: DRUG: Capsaicin 8%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin on Pneumonia Prognosis in Elderly Patients
Status: UNKNOWN
Conditions: Community-Acquired Pneumonia
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioural Change Techniques for Physical Activity and Exercise Adherence Among People With Parkinson's
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Parkinson's Exercise and Education Programme|BEHAVIORAL: Parkinson's Exercise and Education Programme and Behavioural Change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers
Status: TERMINATED
Conditions: HER2-positive Breast Cancer|HER2-positive Gastric Cancer|HER2-positive Colorectal Cancer|HER2-expressing Non-small Cell Lung Cancer
Interventions: DRUG: SBT6050|DRUG: trastuzumab deruxtecan|DRUG: tucatinib|DRUG: trastuzumab|DRUG: capecitabine|DRUG: trastuzumab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Aspirin for the Prevention of Renal Artery Stenosis in Renal Transplantation Recipients
Status: UNKNOWN
Conditions: Renal Transplant
Interventions: DRUG: Aspirin 100mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?
Status: COMPLETED
Conditions: Phrenic Nerve Palsy
Interventions: PROCEDURE: Saline|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Dry Needle and Massotherapy on Tolerance Effort and Soreness
Status: UNKNOWN
Conditions: Delayed Onset Muscle Soreness
Interventions: DEVICE: Dry needling|DEVICE: Massotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Debulking Surgery in Ovarian Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Ovary|Malignant Neoplasm of Fallopian Tube|Malignant Neoplasm of Peritoneum
Interventions: PROCEDURE: Diagnostic laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GliflOzin in eLderly Diabetic patiENts: A praGmatic Intraclass Evaluation Trial
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin|DRUG: Dapagliflozin|DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOLACEA-H in Heparin-sparing Haemodialysis
Status: NOT_YET_RECRUITING
Conditions: Dialysis Membrane Reaction
Interventions: DEVICE: SOLACEA-H/HYDROLINK-NVU|DEVICE: HYDROLINK-NVU/SOLACEA-H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Compartment Block in Acute and Chronic Pain Management in Hip Fracture Patients
Status: COMPLETED
Conditions: Chronic Hip Pain
Interventions: DRUG: Fascia iliaca compartment block|DRUG: Ropivacaine|DEVICE: ultrasound|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impacts of Intraperitoneal Pressure and CO2 Gas on Surgical Peritoneal Environment
Status: COMPLETED
Conditions: Laparoscopic Hysteretctomy With Promontofixation
Interventions: DEVICE: Fisher and Paykel Humidifier (MR860AEU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study to Evaluate and Compare the Efficacy and Safety of XZP-3621 Versus Crizotinib
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: XZP-3621|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Leukemia|Pediatric Cancer
Interventions: DRUG: Epratuzumab|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mesna|PROCEDURE: Infusion of NK cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
Status: RECRUITING
Conditions: Insomnia Chronic|Dementia
Interventions: BEHAVIORAL: Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare DB-1303/BNT323 Versus T-DM1 in Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: DB-1303/BNT323|DRUG: T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous C.E.R.A. for the Treatment of Anemia in Pre-Dialysis Patients.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [C.E.R.A.]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Sensitivity in Esophagus
Interventions: DRUG: AZD1386|DRUG: Placebo to AZD1386
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Establishment of a Personalized Pharmaceutical Plan in Renal or Hepatic Transplant Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Personalized Pharmaceutical Plan After Transpantation
Interventions: BEHAVIORAL: PPP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Chronic Self-management Education on Behavioral and Clinical Outcomes
Status: RECRUITING
Conditions: Rheumatic Fever|Rheumatic Diseases
Interventions: BEHAVIORAL: Self-management education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fenofibrate in Dyslipidemia and Metformin-Controlled Diabetes
Status: COMPLETED
Conditions: Dyslipidemia/Glucose Metabolism Disorder
Interventions: DRUG: fenofibrate and metformin combination (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Cancer Treatment-Induced Thrombocytopenia
Interventions: DRUG: QL0911|DRUG: QL0911 plus Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC
Status: RECRUITING
Conditions: Advanced Pancreatic Ductal Adenocarcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: AGEN1423|DRUG: Botensilimab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma and Hydrodissection for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: platelet rich plasma|DRUG: Normal saline|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab With Preoperative Chemoradiotherapy for LA-EGJ
Status: UNKNOWN
Conditions: PD-1|Chemoradiotherapy|Gastroesophageal Junction Cancer
Interventions: DRUG: PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Motivations for Moms-to-be Study
Status: COMPLETED
Conditions: Weight Gain|Pregnancy|Stress, Emotional|Exercise|Nutrition
Interventions: BEHAVIORAL: Healthy Eating and Physical Activity|BEHAVIORAL: Stress Reduction and Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive Adults
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Human Immunodeficiency Virus
Interventions: BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: Placebo (NaCl 0.9%) vaccine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Sleep Apnea, Obstructive|Anovulation|Polycystic Ovarian Syndrome
Interventions: DEVICE: CPAP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study Comparing Dinaciclib Versus Ofatumumab in Patients With Refractory Chronic Lymphocytic Leukemia (P07714)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Dinaciclib|DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Ultrasound Supra-inguinal Fascia Iliaca Block vs Femoral Nerve Block
Status: COMPLETED
Conditions: Hip Fracture
Interventions: PROCEDURE: Locoregional analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE