pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset|Mild Cognitive Impairment|Moderate Dementia
Interventions: DRUG: Emtriva Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Evaluation of Oral Nutrition Supplements in Patients at Risk for Mucositis Undergoing Cancer Treatment
Status: COMPLETED
Conditions: Esophagitis|Malignant Neoplasm|Mucositis
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplementation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Procarbazine Hydrochloride Capsule (Natulan®) Clinical Trial Protocol
Status: UNKNOWN
Conditions: Advanced Hodgkin's Lymphoma
Interventions: DRUG: Natulan|DRUG: ABVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Corneal Aberrations and Visual Outcomes in AcrySof IQ Toric Patients Versus Limbal Relaxing Incision (LRI) Patients
Status: WITHDRAWN
Conditions: Cataracts
Interventions: DEVICE: Toric|PROCEDURE: Limbal Relaxing Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: NNC0519-0130|DRUG: Placebo|DRUG: Trizepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older
Status: COMPLETED
Conditions: Infections, Papillomavirus|Papillomavirus Vaccines
Interventions: BIOLOGICAL: Cervarix|BIOLOGICAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Significance of Detecting CEA and CK20 mRNA-positive Cells in Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer|Circulating Tumor Cell
Interventions: DEVICE: CTC/DTC count
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Protein From Complementary Foods on Infant Growth, Body Composition and Gut Health
Status: COMPLETED
Conditions: Infant Growth|Infant Body Fat|Infant Gut Microbiome
Interventions: BEHAVIORAL: a high-protein complementary diet with meat|BEHAVIORAL: a high-protein complementary diet with dairy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Harmonica Playing in Improving Lung Function Among COPD Patients
Status: RECRUITING
Conditions: COPD
Interventions: BEHAVIORAL: Harmonica playing program plus basic PR care with routine follow-up|BEHAVIORAL: Basic PR care with routine follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine Based Chemotherapy Followed by Haploidentical Lymphocyte Infusion for Elderly Patients With AML
Status: COMPLETED
Conditions: AML
Interventions: DRUG: Decitabine 20 mg/m²/day for 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Raltegravir (MK-0518) in Healthy Japanese Male Participants (MK-0518-851)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Anesthesia, Using Bispectral Index as the Control Variable, During Liver Transplantation
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: DEVICE: Closed loop administration|DEVICE: Manual administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Docetaxel|DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hypertension|Hyperkalemia
Interventions: DRUG: patiromer|DRUG: patiromer|DRUG: patiromer|DRUG: patiromer|DRUG: patiromer|DRUG: patiromer|DRUG: losartan|DRUG: spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Predictive Value of ERCC1 in Esophageal Cancer Patients Treated With Paclitaxel and Cisplatin
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: paclitaxel and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Study Evaluating the Effect of Parathyroid Hormone (PTH) Lowering On Erythropoietin Consumption in Calcitriol-Resistant Patients
Status: COMPLETED
Conditions: Moderate to Severe Secondary Hyperparathyroidism|Stage 5 Chronic Kidney Diseases
Interventions: DRUG: Paricalcitol|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness
Status: COMPLETED
Conditions: Influenza|Influenza -Like Illness
Interventions: DRUG: Norketotifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Actinic Keratosis Treatment Following Cryosurgery
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: imiquimod cream|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Lyme Vaccine Study
Status: COMPLETED
Conditions: Prophylaxis of Lyme Borreliosis
Interventions: BIOLOGICAL: Multivalent recombinant OspA Lyme Borreliosis Vaccine|BIOLOGICAL: Multivalent recombinant OspA Lyme Borreliosis Vaccine|BIOLOGICAL: Multivalent recombinant OspA Lyme Borreliosis Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Phenotype and Clinical Intervention of High BCAA Type of PCOS
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: protein restricted diet combined with vitamin D intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3209590 in Chinese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3209590|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace
Status: COMPLETED
Conditions: Tobacco Use
Interventions: DRUG: 3 mg/mL nicotine strength e-liquid|DRUG: 6 mg/mL nicotine strength e-liquid|DRUG: 12 mg/mL nicotine strength e-liquid|DRUG: 24 mg/mL nicotine strength e-liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a Booster Dose of Pneumo 23® in 12 to 18 Months-Old Children Primed With Prevnar
Status: COMPLETED
Conditions: Streptococcus Pneumoniae
Interventions: BIOLOGICAL: Pneumo 23|BIOLOGICAL: Prevnar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In Utero Enzyme Replacement Therapy for Lysosomal Storage Diseases
Status: RECRUITING
Conditions: MPS I|MPS II|MPS IVA|MPS VI|Mps VII|Gaucher Disease, Type 2|Gaucher Disease, Type 3|Pompe Disease Infantile-Onset|Wolman Disease
Interventions: DRUG: Aldurazyme (laronidase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WAMIF : Young Women Presenting Acute Myocardial Infarction in France
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Women Over 18 and Under 50 Years of Age
Interventions: OTHER: Specific blood sample of women under 50 years with acute MI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives
Status: RECRUITING
Conditions: COVID-19|Quality of Life|Posttraumatic Stress Disorder|Cognitive Impairment|Social Behavior
Interventions: BEHAVIORAL: COVID19-severe Patient|BEHAVIORAL: family of COVID19-severe Patient
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjects With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: palifosfamide-tris|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: LY3410738|DRUG: Itraconazole|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) in Hispanics With Diabetes Mellitus Type 2 (T2DM) and Role of Treatment
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: pioglitazone-placebo|DRUG: pioglitazone|DIETARY_SUPPLEMENT: Vitamin E|DRUG: pioglitazone-placebo|DIETARY_SUPPLEMENT: Vitamin E|DRUG: Vitamin E-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm
Status: TERMINATED
Conditions: Laryngospasm
Interventions: DRUG: Lidocaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interventions for Children With Attention and Reading Disorders
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Reading Disabilities
Interventions: DRUG: Methylphenidate|BEHAVIORAL: Intensive reading instruction|BEHAVIORAL: Parent Training|DRUG: Mixed Salt Amphetamine|DRUG: Atomoxetine|DRUG: Guanfacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Hip Fractures|Dementia|Cognitive Impairment|Cognitive Decline
Interventions: OTHER: Nerve block+standard anesthesia|DRUG: Intravenous lidocaine+standard anesthesia|DRUG: Bupivacaine liposome|DEVICE: Ultrasound-guided nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Bintrafusp Alfa in Operable and Untreated Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: bintrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Techniques for Recreation of Anterior Cruciate Ligament Anatomic Footprint
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Anterior Cruciate Ligament Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Emergence Agitation by Sevoflurane for Intraoperative Sedation Associated With Caudal Block
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: low dose sevoflurane group|DRUG: high dose sevoflurane group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Superficial Cervical Plexus Versus Retrolaminar Block in Parotid Surgeries
Status: UNKNOWN
Conditions: Supportive Care
Interventions: PROCEDURE: Superficial cervical plexus with auriculotemporal nerve blocks|PROCEDURE: Cervical retrolaminar with auriculotemporal nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 68Ga-NODAGA-RGD PET/ CT for Tumoral Neoangiogenesis
Status: TERMINATED
Conditions: Pathological Angiogenesis
Interventions: DRUG: 68Ga-NODAGA-RGD PET/CT|RADIATION: 18F-FDG PET/CT|RADIATION: 18F-FET PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Substrate Ablation in Post-myocardial Patients Undergoing Defibrillator Implantation.
Status: UNKNOWN
Conditions: Heart Failure|Myocardial Infarction|Ventricular Tachycardia
Interventions: PROCEDURE: Ventricular tachycardia substrate ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Thymoma and Thymic Carcinoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Neurocognitive and Immunological Study of a New Formula for Healthy Infants
Status: UNKNOWN
Conditions: Infant Development
Interventions: DIETARY_SUPPLEMENT: New infant formula|DIETARY_SUPPLEMENT: Standard infant formula|DIETARY_SUPPLEMENT: Breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dosimetry Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma (LYMRIT-37-02)
Status: WITHDRAWN
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Betalutin with lilotomab dose 1|DRUG: Betalutin with lilotomab dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: INCB086550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Secondary Infection
Interventions: DRUG: Retapamulin 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Trial to Investigate the Efficacy and Safety of Tolvaptan in Patients With Hyponatremia in SIADH
Status: COMPLETED
Conditions: Syndrome of Inappropriate Antidiuretic Hormone Secretion
Interventions: DRUG: Tolvaptan Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Behavioral Therapy for Insomnia Co-existing With COPD
Status: COMPLETED
Conditions: Insomnia|COPD|Chronic Obstructive Pulmonary Disease|Fatigue
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: COPD Education|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ulinastatin Preventing Postoperative Hepatic Failure in Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Ulinastatin|DRUG: Diammonium glycyrrhizinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Early Changes of Chromogranin A Levels in Patients With Neuroendocrine Tumours Treated With PRRT
Status: COMPLETED
Conditions: Early Release of Chromogranin A (CgA)
Interventions: DIAGNOSTIC_TEST: early release of chromogranin A (CgA) in patients with neuroendocrine tumours (NET) treated with peptide receptor radionuclide therapy (PRRT).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurocognitive Exercises for Ankle Instability
Status: NOT_YET_RECRUITING
Conditions: Ankle Sprains
Interventions: OTHER: Neurocognitive Enriched Exercise|OTHER: Standart Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Momordica Charantia Administration on Type 2 Diabetes Mellitus, Insulin Sensitivity and Insulin Secretion
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Momordica charantia|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU
Status: COMPLETED
Conditions: COVID-19|Mild to Moderate
Interventions: DRUG: Baricitinib Oral Tablet|DRUG: Tocilizumab Injection|DRUG: Netakimab|OTHER: Standard of care therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Seroquel- Agitation Associated With Dementia
Status: COMPLETED
Conditions: Alzheimer's Disease|Vascular Dementia
Interventions: DRUG: Quetiapine Fumarate|DRUG: Quetiapine Fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Responder Analysis of the Effectiveness of Manual Therapy and Exercise Versus Usual Care in Patients With Chronic Nonspecific Neck Pain
Status: UNKNOWN
Conditions: Chronic Nonspecific Neck Pain
Interventions: OTHER: Manual Therapy and Exercise (Physiotherapy Intervention)|OTHER: Usual Care (Physiotherapy Intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer of Subjects From Subutex/Suboxone to RBP-6300
Status: COMPLETED
Conditions: Opioid Related Disorder
Interventions: DRUG: RBP-6300|DRUG: Subutex®/Suboxone®|DRUG: Placebo for RBP-6300|DRUG: Placebo for Subutex®/Suboxone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety of GSK's Combined DTPa-HBV-IPV/Hib Vaccine in Indian Infants at 2 Diff Vaccination Schedules
Status: COMPLETED
Conditions: Diphtheria|Acellular Pertussis|Tetanus|Haemophilus Influenzae Type b|Hepatitis B|Poliomyelitis
Interventions: BIOLOGICAL: DTPa-HBV-IPV/Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the "CrossBoss First" Trial
Status: COMPLETED
Conditions: Arteriosclerosis|Coronary Artery Disease|Myocardial Ischemia|Coronary Disease
Interventions: PROCEDURE: CrossBoss Catheter|PROCEDURE: Antegrade Wire Escalation Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Albuvirtide in Combination With 3BNC117 in Virologically Suppressed Subjects With HIV-1 Infection
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: DRUG: Albuvirtide|DRUG: 3BNC117
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes
Status: COMPLETED
Conditions: Brain Concussion|Post-Concussion Syndrome
Interventions: DEVICE: London Health Sciences Centre - Compression Vest|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Myofascial Release on Muscle Mechanical Properties
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: 30 rolls per minute(30RPM)|OTHER: 15 rolls per minute(15RPM)|OTHER: self-determined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Statin Treatment on Insulin Sensitivity During Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Simvastatin 80mg|DRUG: Simvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRIDE. Assessment of the Efficacy, Adherence and Tolerability of the Single Pill Combination Bisoprolol/Perindopril
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Infarction|Arterial Hypertension
Interventions: DRUG: in daily everyday routine practice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Examining the Efficacy of tDCS in the Attenuation of Epileptic Paroxysmal Discharges and Clinical Seizures
Status: COMPLETED
Conditions: Ohtahara Syndrome
Interventions: DEVICE: High-definition (HD) transcranial direct current stimulator, HD-tDCS with 4x1 HD adaptor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive|Recurrent Acute Lymphoblastic Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Acute Lymphoblastic Leukemia|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive|t(9;22)
Interventions: DRUG: Dexamethasone|DRUG: Ponatinib Hydrochloride|BIOLOGICAL: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (RIGHT HEART III Study - Right Ventricular Hemodynamic Evaluation and Response to Treatment)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension (PAH)
Interventions: DRUG: Riciguat Group|DRUG: Macitentan Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Persistent Distal Occlusion After Successful Proximal Recanalization in Thrombectomy
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute Thrombotic
Interventions: DEVICE: Mechanical thrombectomy in proximal large vessels|DEVICE: Rescue mechanical thrombectomy in distal vessels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Linagliptin/Metformin FDC|DRUG: Linagliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversalis Fascia Plane Block vs Transversus Abdominis Plane Block In Pediatric Surgeries
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: OTHER: Transversalis Fascia Plane Block|OTHER: Transversus Abdominis Plane Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)
Status: ACTIVE_NOT_RECRUITING
Conditions: OSA
Interventions: DRUG: AD109|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: MK-8892
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Prevention of Venous Thromboembolism
Interventions: BIOLOGICAL: bovine heparin|BIOLOGICAL: Porcine heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic on Atopic Dermatitis in Infant
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium longum CCFM1029|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)
Status: COMPLETED
Conditions: Pain, Postoperative|Crohn Disease|Inflammatory Bowel Diseases|Colorectal Cancer|Gastrointestinal Cancer|Gastrointestinal Disease|Digestive System Disease|Pain|Pain, Neuropathic|Intestinal Disease
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine/epinephrine/dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY
Status: COMPLETED
Conditions: Acute Pain|Chronic Pain|Postoperative Pain|Anesthesia|Regional Anesthesia Morbidity|Anesthesia, Local|Anesthesia Complication|Hyperalgesia|Intraoperative Complications|Intraoperative Neurological Injury|Intraoperative Injury|Postoperative Nausea and Vomiting|Postoperative Cognitive Dysfunction|Neuropathic Pain
Interventions: PROCEDURE: Local infiltrative anaesthesia|PROCEDURE: Erector spine plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Regimens of Pegylated Interferon and Lamivudine Combination Therapy in Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Pegylated Interferon|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Non-Small Cell Lung Cancer
Interventions: DRUG: CC-223, erlotinib|DRUG: CC-223, oral azacitidine|DRUG: CC-223, oral azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury
Status: TERMINATED
Conditions: Contrast-induced Nephropathy|Chronic Kidney Diseases
Interventions: DEVICE: Low-frequency therapeutic ultrasound (LOTUS)|DEVICE: LOTUS System with Ultrasound Disabled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Anxiety in Pediatric Reconstructive Burn Patients: The Role of Virtual Reality Hypnosis
Status: COMPLETED
Conditions: Anxiety
Interventions: DEVICE: Virtual Reality Hypnosis|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Food Study of Sumatriptan Succinate Tablets 100 mg to Imitrex® Tablets 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sumatriptan Succinate Tablets 100 mg|DRUG: Imitrex® Tablets 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Individualized Rituximab in Maintaining Remission of Moderate and Severe Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Autoimmune Diseases
Interventions: DRUG: Standard dose of rituximab|DRUG: Individualized dose of rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danish Evaluation of Early Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure
Status: RECRUITING
Conditions: Atrial Fibrillation|Heart Failure
Interventions: PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of Sitagliptin on β Cell Function in Patients With Adult-onset Latent Autoimmune Diabetes (LADA)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: sitagliptin|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Effectiveness of Alprostadil,Sodium Ferulate and Dopamine in Pediatric Acute Kidney Injury
Status: UNKNOWN
Conditions: Children AKI Patients
Interventions: DRUG: Alprostadil|DRUG: Sodium Ferulate|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Failure.
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: L Carnitine ( low dose)|DRUG: L-Carnitine ( high dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Spinal Versus Epidural Analgesia in Laparotomic Liver Surgery
Status: UNKNOWN
Conditions: Secondary Malignant Neoplasm of Liver|Liver Diseases|Liver Neoplasms
Interventions: PROCEDURE: Spinal analgesia|PROCEDURE: Epidural analgesia|PROCEDURE: Transversus Abdominis Plane block|PROCEDURE: Surgical wound infiltration|DRUG: Acetaminophen|DRUG: Ketorolac|DRUG: Ropivacaine|DRUG: Sufentanil|DRUG: Ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm|Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder)|Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Interventions: DEVICE: Medtronic Endurant II or Endurant IIs Stent Graft System|DEVICE: Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transumbilical Laparoscopy-assisted Appendectomy
Status: UNKNOWN
Conditions: Appendicitis Acute
Interventions: PROCEDURE: Transumbilical Laparoscopic-Assisted Appendectomy|PROCEDURE: 3-port laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Marrow Irradiation With High Dose Melphalan Prior to Autologous Transplant for Relapsed or Refractory Multiple Myeloma (BMT-03)
Status: COMPLETED
Conditions: Multiple Myeloma, Relapsed|Multiple Myeloma, Refractory to Standard Treatment
Interventions: RADIATION: Total Marrow Irradiation|DRUG: Melphalan|DRUG: Filgrastim (G-CSF)|PROCEDURE: Autologous transplant|RADIATION: Total Marrow Irradiation|DRUG: Melphalan|DRUG: Filgrastim (G-CSF)|PROCEDURE: Autologous transplant|RADIATION: Total Marrow Irradiation|DRUG: Melphalan|DRUG: Filgrastim (G-CSF)|PROCEDURE: Autologous transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of an Exclusive Cold Snare Polypectomy Snare for the Removal of Diminutive Colorectal Polyps
Status: COMPLETED
Conditions: Diminutive Colorectal Polyp|Cold Snare Polypectomy|Polypectomy Snare|Complete Resection Rate|Postpolypectomy Bleeding
Interventions: DEVICE: exclusive cold polypectomy snare (Exacto cold snare, product number 00711115)|DEVICE: Regular polypectomy snare (Snare Master, SD-210U-10)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consumer Responses to Alcohol Warnings
Status: COMPLETED
Conditions: Alcohol Drinking
Interventions: BEHAVIORAL: Mouth cancer warning|BEHAVIORAL: Throat cancer warning|BEHAVIORAL: Voice box (larynx) warning|BEHAVIORAL: Esophagus cancer warning|BEHAVIORAL: Liver cancer warning|BEHAVIORAL: Colon and rectum cancer warning|BEHAVIORAL: Breast cancer|BEHAVIORAL: Cancer (generic, not site-specific)|BEHAVIORAL: Addiction and neurological changes|BEHAVIORAL: Hypertension|BEHAVIORAL: Liver damage|BEHAVIORAL: Harm to fetus|BEHAVIORAL: Dementia|BEHAVIORAL: Impaired sleep|BEHAVIORAL: Drinking guidelines|BEHAVIORAL: Control|BEHAVIORAL: Road injuries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Afatinib With Paclitaxel for Neoadjuvant Therapy of TNBC and Research of Biomarkers of Afatinib
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD|Smoking
Interventions: DRUG: Osmotic-Release Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-acne Efficacy of a Dermo-cosmetic Product Associated With the Fixed Combination Adapalene 0.1%/ Benzoyl Peroxide 2.5% Treatment Versus This Treatment Associated With a Standard Moisturizer in Male and Female Subjects Presenting With Mild to Moderate Acne
Status: COMPLETED
Conditions: Acne
Interventions: COMBINATION_PRODUCT: Epiduo|DRUG: Salicylic Acid|OTHER: Hydréane légère
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
Status: RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: ECBT-I|BEHAVIORAL: HE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin for Oxidative Stress and Inflammation
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Instrumented Data Exchange for Ataxia Study
Status: COMPLETED
Conditions: Spinocerebellar Ataxia Type 1|Spinocerebellar Ataxia Type 2|Spinocerebellar Ataxia Type 3|Spinocerebellar Ataxia Type 6|Friedreich Ataxia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of AT2101 (Afegostat Tartrate) in Adult Patients With Type 1 Gaucher Disease Currently Receiving Enzyme Replacement Therapy
Status: COMPLETED
Conditions: Gaucher Disease, Type 1|Type 1 Gaucher Disease|Gaucher Disease
Interventions: DRUG: Afegostat tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Status Epilepticus Treatment Times
Status: RECRUITING
Conditions: Status Epilepticus
Interventions: OTHER: Quality improvement bundle|OTHER: Quality improvement bundle and local PDSA cycles with central support|OTHER: Quality improvement bundle and local PDSA cycles without central support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Catumaxomab in Patients With Non-Muscle-Invasive Bladder Cancer Who Have Failed or Are Intolerant to BCG Vaccine
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Catumaxomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Survival in Puerperae by Electrical Impedance Tomography
Status: COMPLETED
Conditions: Postpartum Period|Sepsis|Respiratory Distress Syndrome,Adult|HELLP Syndrome
Interventions: OTHER: Sepsis|OTHER: HELLP Syndrome|OTHER: Respiratory Distress Syndrome Adult
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aztreonam for Inhalation (AI) in Patients With Cystic Fibrosis & P. Aeruginosa Infection
Status: COMPLETED
Conditions: Cystic Fibrosis|CF|Lung Infection|Pseudomonas Aeruginosa
Interventions: DRUG: Aztreonam for Inhalation (AI)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Pregnancy Related|Hypocalcemia|Parturition Complication
Interventions: DRUG: Calcium Gluconate|DRUG: Calcium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conventional Versus Conservative Caries Removal in Primary Teeth
Status: UNKNOWN
Conditions: Dental Caries Extending Into Dentin
Interventions: PROCEDURE: Carious dentin removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing 6-mercaptopurine Therapy in Pediatric Acute Lymphoblastic Leukemia by Using Allopurinol
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute, Childhood
Interventions: DRUG: Allopurinol|DRUG: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saving Lives With Better Gestational Age Estimation
Status: UNKNOWN
Conditions: Premature Birth
Interventions: BEHAVIORAL: Education & paper based calendar|BEHAVIORAL: Education & SMS system|BEHAVIORAL: Education & smart-phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using Real-Time Functional Brain Imaging to Enhance Recovery From TBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: RT fMRI|BEHAVIORAL: Cognitive Training|BEHAVIORAL: Control RT fMRI|BEHAVIORAL: Control Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Technology to Improve Physical Activity Levels Among Postmenopausal Women (The Active & Aware Study)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Technology-Based Physical Activity Promotion|BEHAVIORAL: Pedometer Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tenofovir Disoproxil Fumarate/Emtricitabine/Efavirenz Versus Combivir/Efavirenz in Antiretroviral-Naive HIV-1 Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine (FTC)|DRUG: Tenofovir Disoproxil Fumarate (TDF)|DRUG: Efavirenz (EFV)|DRUG: FTC/TDF|DRUG: FTC/TDF/EFV|DRUG: Lamivudine/zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NOV120101 Phase 2 Study in NSCLC Patients With Aquired Resistance to 1st Generation EGFR Tyrosine Kinase Inhibitors
Status: COMPLETED
Conditions: Increased Drug Resistance
Interventions: DRUG: NOV120101 (Poziotinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of Functional Anesthetic and Provocative Discography in the Surgical Treatment of Discogenic Pain
Status: WITHDRAWN
Conditions: Discogenic Pain|Low Back Pain
Interventions: PROCEDURE: Functional anesthetic discography|PROCEDURE: Provocative Discography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Evaluation of Budesonide for Prevention of Esophageal Strictures After Endotherapy
Status: COMPLETED
Conditions: Esophageal Stricture
Interventions: DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Anxiety in PD
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Active Transcutaneous auricular vagus nerve stimulation|DEVICE: Sham Transcutaneous auricular vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM)
Status: TERMINATED
Conditions: Mesothelioma, Malignant
Interventions: DRUG: Placebo|DRUG: Amatuximab|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Trunk Exercises on Upper Extremity and Respiratory Functions in DMD
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne|Upper Extremity|Respiratory Functions
Interventions: OTHER: Trunk-oriented exercise program|OTHER: Conventional exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study
Status: COMPLETED
Conditions: Liver Failure|Carcinoma, Hepatocellular
Interventions: PROCEDURE: Remote Ischemic Conditioning (RIC)|DEVICE: Pneumatic tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of SyB C-1101 and Azacytidine in Patients With Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: SyB C-1101 and Azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT