pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Deep Neuromuscular Block and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity in Shoulder Surgery Using a Deltopectoral Approach
Status: UNKNOWN
Conditions: Shoulder Pain|Anesthesia
Interventions: PROCEDURE: Deep neuromuscular block|PROCEDURE: Moderate neuromuscular block|DRUG: Neuromuscular Blocking Agents and reversing agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Metformin|RADIATION: Salvage Radiotherapy SRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CVD Risk and Health in Postmenopausal Phytoestrogen Users
Status: COMPLETED
Conditions: Bone Diseases|Cardiovascular Diseases|Coronary Disease|Depression|Heart Diseases|Myocardial Ischemia|Osteoporosis|Postmenopause
Interventions: BEHAVIORAL: dietary supplements|DRUG: genistein|BEHAVIORAL: diet, soy proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cone Beam Computed Tomography for Breast Imaging
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Computed Tomography|RADIATION: Computed Tomography|RADIATION: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
Status: COMPLETED
Conditions: Functional Constipation|Irritable Bowel Syndrome With Constipation
Interventions: DRUG: Linaclotide 72 μg (FC Participants)|DRUG: Placebo (FC Participants)|DRUG: Linaclotide 145 μg (IBS-C Participants)|DRUG: Linaclotide 290 μg (IBS-C Participants)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing the Effect of a School-based Prevention Program by Teacher Involvement
Status: UNKNOWN
Conditions: Primary Prevention
Interventions: BEHAVIORAL: Experimental: Prevention Program "young In Favor of Myself", active teachers|BEHAVIORAL: Experimental: Prevention Program "young In Favor of Myself", no teacher involvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Environmental Enteropathy and Malnutrition in Pakistan
Status: COMPLETED
Conditions: Malnutrition, Child|Enteropathy|Vaccine Response Impaired|Stunting|Gastrointestinal Disease
Interventions: OTHER: Nutritional education|DIETARY_SUPPLEMENT: Ready to Use Therapeutic Food|PROCEDURE: Upper gastrointestinal endoscopy with biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tension-free Vaginal Tape Obturator for the Treatment of Urinary Incontinence -Long-term Follow-up
Status: COMPLETED
Conditions: Urinary Incontinence,Stress|Urinary Incontinence, Urge
Interventions: DEVICE: TVT-O
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety of ComBe Five (Liquid) in Healthy Vietnamese Children Aged From 8 - 10 Weeks as a 3-dose Series, Interval for Each Dose is 4 Weeks
Status: COMPLETED
Conditions: Safety, Pentavalent Vaccine
Interventions: BIOLOGICAL: ComBe Five (Liquid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BEHAVIORAL: Multi-Family Group Treatment|BEHAVIORAL: SCI Education Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Calcium 500 mg and Vitamin D3 1000 IU Chewable Tablet on Intestinal Calcium Absorption
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Calcichew D3|DRUG: Noncarbonated Water
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Appendicitis Acute|Laparoscopic Surgery
Interventions: DEVICE: Technique used for closing the appendiceal stump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Altered Chemotherapy Sequencing During Neoadjuvant Therapy for Patients With Stage II or III Rectal Adenocarcinoma
Status: WITHDRAWN
Conditions: Stage II Rectal Cancer|Stage III Rectal Cancer
Interventions: DRUG: Capecitabine|DRUG: 5-FU|DRUG: Leucovorin|DRUG: Oxaliplatin|RADIATION: radiation|PROCEDURE: total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Remifentanil in Preventing Emergence Agitation
Status: RECRUITING
Conditions: Emergence Agitation
Interventions: DRUG: Remifentanil|DRUG: N2O|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors
Status: TERMINATED
Conditions: Pancreatic Neuroendocrine Tumors (pNET)
Interventions: DRUG: BEZ235|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation
Status: WITHDRAWN
Conditions: HIV-1 Infection
Interventions: DRUG: Pravastatin sodium|DRUG: Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate|DRUG: Pravastatin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gentrix™ Versus Biological or Prosthetic Mesh
Status: TERMINATED
Conditions: Ventral Incisional Hernia
Interventions: DEVICE: Gentrix™ Surgical Matrix (Treatment)|DEVICE: Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Suboccipital Muscle Release Combined With Sustained Natural Apophyseal Glides in Patients With Chronic Tension Type Headache
Status: ACTIVE_NOT_RECRUITING
Conditions: Tension-Type Headache
Interventions: PROCEDURE: sustained natural apophyseal glides (SNAGS)|PROCEDURE: suboccipital muscle release|PROCEDURE: Supplemental therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Niños Sanos, Familia Sana - A Multi-Intervention Program to Prevent Childhood Obesity in Mexican-Heritage Children in Rural California
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Ninos Sanos Familia Sana
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Omega-3 Fatty Acid Supplements on Fibromyalgia Symptoms
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Omega-3 (oil)|DIETARY_SUPPLEMENT: Fatty Acids (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Learning Efficacy and Motivation of Medical Students in Clinical Training With Virtual Reality
Status: RECRUITING
Conditions: Motivation|Efficacy, Self
Interventions: OTHER: Virtual Reality 360 interactive video|OTHER: Traditional mini-lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Pharmacokinetics and Safety of Different Forms and Formulations of AZD9496 in Healthy Subjects
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: AZD9496 (Reference)|DRUG: AZD9496 Variant A|DRUG: AZD9496 Variant B|DRUG: AZD9496 Variant C|DRUG: AZD9496 Variant D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Plus Stereotactic Body Radiotherapy in II and III Line of Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cancer Metastatic
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vicryl Rapide Versus Nonabsorbable Suture
Status: RECRUITING
Conditions: Traumatic Lacerations
Interventions: DEVICE: Vicryl Rapide absorbable suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study - Effect of Omega-3 on Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Olive Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DEVICE: Thermal stimuli|DEVICE: Pressure stimuli|BEHAVIORAL: Pain ratings|BEHAVIORAL: Pressure pain thresholds (PPT)|BEHAVIORAL: Conditioned pain modulation (CPM) response|BEHAVIORAL: PedMIDAS (Pediatric Migraine Disability Assessment)|DIAGNOSTIC_TEST: Hormonal assessment|OTHER: Pubertal status
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility Study of Biomarkers of Response to Neoadjuvant Paclitaxel in Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: tumor biopsy and blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane
Status: UNKNOWN
Conditions: Hormone Receptor Positive Malignant Neoplasm of Breast|Metastatic Breast Cancer
Interventions: DRUG: Everolimus plus Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Control of Unsupported Paraplegic Standing
Status: UNKNOWN
Conditions: Spinal Cord Injury|Stroke
Interventions: DEVICE: Multi-purpose rehabilitation frame|DEVICE: Surface Functional Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|DRUG: etoposide|DRUG: BCNU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Supplemental Parenteral Nutrition in ICU Patients on Metabolic, Inflammatory and Immune Responses
Status: COMPLETED
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: Supplemental parenteral nutrition (SPN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Dose Bioavailability and Ethnobridging PK Study in Healthy Subjects
Status: COMPLETED
Conditions: Intestinal Disorder|Bowel Diseases, Inflammatory
Interventions: DRUG: TD-1473 [Tablet A]|DRUG: TD-1473 [Tablet B]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pillcam Crohn's Capsule for Monitoring of Panenteric Mucosal Healing in Crohn's Disease Patients With Vedolizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: OTHER: prospective follow-up with videocapsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: BEHAVIORAL: DvtProgram ENERGY|BEHAVIORAL: DvtProgram ENERGY|BEHAVIORAL: DvtProgramENERGY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of Vapendavir in Asthmatic Adults With Symptomatic Human Rhinovirus Infection
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Vapendavir|DRUG: Vapendavir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Hibiscus Sabdariffa Beverage
Status: RECRUITING
Conditions: Markers of Inflammation|Hyperglycemia, Postprandial|Hyperinsulinism
Interventions: DIETARY_SUPPLEMENT: Effect of a Hibiscus sabdariffa beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Evaluate CD19 CAR T (CT032) in Patients With Relapsed and/or Refractory Non-Hodgkin's B Cell Lymphoma
Status: COMPLETED
Conditions: Refractory B-Cell Non-Hodgkin Lymphoma|Relapsed B-cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: CAR-CD19 T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Extra Virgin Olive Oil Oleocanthal Content on Platelet Reactivity
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: D2i2|OTHER: D2i0.5|OTHER: D2i0|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Evaluation of Acupoint Application in the Treatment of Knee Osteoarthritis Joint Pain
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: acupoint application|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Burden of Malaria by Targeting Hotspots of Malaria Transmission
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-lumefantrine combination|BIOLOGICAL: Bacillus thuringiensis|BIOLOGICAL: Long lasting insecticide treated net (LLINs)|BIOLOGICAL: Indoor Residual Spraying (IRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.
Status: TERMINATED
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Autologous DCs derived from PBMC loaded with RNA encoding the human CMV matrix protein pp65-flLAMP plus GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Atorvastatin and Glimepiride Fixed Dose Combination and Atorvastatin and Glimepiride Loose Combination in the Treatment of Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: 1mg Glimepiride/10mg Atorvastatin FDC|DRUG: 2mg Glimepiride/10mg Atorvastatin FDC|DRUG: 3mg Glimepiride/10mg Atorvastatin FDC|DRUG: 4mg Glimepiride/10mg Atorvastatin FDC|DRUG: 1mg Glimepiride/20mg Atorvastatin FDC|DRUG: 2mg Glimepiride/20mg Atorvastatin FDC|DRUG: 3mg Glimepiride/20mg Atorvastatin FDC|DRUG: 4mg Glimepiride/20mg Atorvastatin FDC|DRUG: 1mg Glimepiride|DRUG: 2mg Glimepiride|DRUG: 3mg Glimepiride|DRUG: 4mg Glimepiride|DRUG: 10mg Atorvastatin|DRUG: 20mg Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: desferrioxamine (DFO)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacrospinous Ligament Fixation vs Ischial Spine Fascia Fixation
Status: UNKNOWN
Conditions: Urogenital Prolapse
Interventions: PROCEDURE: ischial spine fascia fixation|PROCEDURE: sacrospinous ligament fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic and Cardiovascular Recovery After the Acute Use of Resveratrol in Overweight and Obesity Individuals
Status: RECRUITING
Conditions: Polyphenols|Cardiovascular Diseases|Autonomic Nervous System
Interventions: DIETARY_SUPPLEMENT: Resveratrol Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MBSR Mechanisms in GAD
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction MBSR Intervention|BEHAVIORAL: Stress Education Control Condition (SE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule Patients
Status: COMPLETED
Conditions: Peripheral Solitary Pulmonary Nodule or Tuberculoma
Interventions: DRUG: Propofol|DRUG: Sulfentanyl|DRUG: Dexmedetomidine|DRUG: Lidocaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Three Injectable Hyaluronic Acid-based Fillers: Art Filler® Fine Lines, Art Filler® Universal and Art Filler® Lips
Status: COMPLETED
Conditions: Loss of Face Volume
Interventions: DEVICE: Intradermal injection (superficial dermis for Art Filler Fine Lines / moderately deep to deep dermis for Art Filler Universal and Art Filler Lips)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block for Spine Surgery
Status: TERMINATED
Conditions: Lumbar Radiculopathy
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Breast Cancer|Prostate Cancer
Interventions: DRUG: LY2606368
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Greenwich Lumbar Stenosis SLIP Study
Status: COMPLETED
Conditions: Spinal Stenosis|Spondylolisthesis
Interventions: PROCEDURE: Lumbar Laminectomy with Instrumented Pedicle Screw Fusion|PROCEDURE: Lumbar Laminectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of AstroStem in Treatment of Alzheimer's Disease
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: AstroStem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ametop Cream in Reducing Pain of Local Anesthetic Infiltration
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ametop cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intelligent Volume Assured Pressure Support to Improve Sleep Quality and Respiratory Events in Patients With Non Invasive Ventilation
Status: COMPLETED
Conditions: COPD|Chronic Hypercapnic Respiratory Failure
Interventions: DEVICE: pressure controlled ventilation BIPAP ST|DEVICE: volume assured pressure support IVAPS|DEVICE: NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (Cost-)Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Cancer Patients
Status: COMPLETED
Conditions: Distress|Anxiety|Depression
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: nitrous oxide and oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Defining the Role of Insulin Resistance in 'Idiopathic' Dilated Cardiomyopathy
Status: TERMINATED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Rosiglitazone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Lactoferrin Infant Feeding Trial - LIFT_Canada
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant|Very Low Birth Weight Infant|Morbidity;Newborn
Interventions: DIETARY_SUPPLEMENT: Bovine Lactoferrin|OTHER: No Bovine Lactoferrin added
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility of Radiotherapy and Concomitant Gemcitabine and Oxaliplatin in Locally Advanced Pancreatic Cancer and Distal Cholangiocarcinoma
Status: COMPLETED
Conditions: Locally Advanced and Unresectable, But Non-metastatic Pancreatic Adenocarcinoma or Cholangiocarcinoma
Interventions: DRUG: Association of gemcitabine, oxaliplatin and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine Given With Prevnar 13 in Healthy Infants
Status: TERMINATED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Multivalent|BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drugs to Reduce the Side Effects of Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: dexamethasone|DRUG: granisetron hydrochloride|DRUG: metoclopramide hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Warning of Diabetic Peripheral Neuropathy by Using Infrared Thermography and the Effectiveness of Electroacupuncture in Its Prevention
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: infrared thermography (IRT)|PROCEDURE: Basal therapy+EA|OTHER: Basal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Esophageal Cancer|GastroEsophageal Cancer
Interventions: DRUG: Nivolumab|DRUG: Relatlimab|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab, erlotinib|DRUG: bevacizumab|DRUG: bevacizumab|DRUG: low dose capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Superficial Femoral Artery Stenosis|Popliteal Artery Stenosis
Interventions: DEVICE: ChampioNIR Ridaforolimus Eluting Peripheral Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preterm Premature Rupture of Membranes, Outpatient Management vs Inpatient Management
Status: UNKNOWN
Conditions: Preterm Premature Rupture of Membranes
Interventions: OTHER: outpatient management|OTHER: Inpatient management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Technology in Improving Asthma Management In School Staff
Status: COMPLETED
Conditions: Asthma in Children
Interventions: OTHER: Ebook Asthma First Aid in School Training|OTHER: Face-To-Face Asthma First Aid in Schools Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence of Two Different Drug Product Batches of Dabigatran Etexilate Following Oral Administration in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran polymorph I (≈ 83%) and polymorph II (≈17%)|DRUG: Dabigatran polymorph I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Marginal Bone Loss and Associated Factors Around Ziacom Dental Implants With Different Prosthetic Connection
Status: RECRUITING
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Ziacom Galaxy dental implant with internal connical prosthetic connection|DEVICE: Ziacom Zinic dental implant with internal hexagonal prosthetic connection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
Status: RECRUITING
Conditions: Human Papillomavirus Type 16|Cervical Intraepithelial Neoplasia Grade II|Cervical Intraepithelial Neoplasia, Grade III
Interventions: DRUG: pNGVL4aCRTE6E7L2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PP13 and Doppler Study to Predict Preeclampsia
Status: UNKNOWN
Conditions: Preeclampsia
Interventions: DRUG: Progesterone|DRUG: Low molecular weight Heparin|DRUG: No Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: n-3 Enriched Nutrition Therapy and Postoperative Cognitive Dysfunction After Cardiac Surgery
Status: TERMINATED
Conditions: Delirium, Dementia, Amnestic, Cognitive Disorders|Postoperative Cognitive Dysfunction
Interventions: DIETARY_SUPPLEMENT: n-3 enriched nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz 600mg|DRUG: Efavirenz 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly ONe-Day WatER-only Fasting InterventionaL Trial for Low-Density Lipoprotein Cholesterol Reduction
Status: COMPLETED
Conditions: Intermittent Fasting
Interventions: BEHAVIORAL: Intermittent Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of a Phospholipid Drink on Cognitive Performance Under Acute Stress
Status: COMPLETED
Conditions: Cognitive Performance (Focus)
Interventions: DIETARY_SUPPLEMENT: Phospholipid drink|DIETARY_SUPPLEMENT: Placebo milk drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Can MRI Evaluate Beta-blocker Response in Portal Hypertension?
Status: UNKNOWN
Conditions: Liver Cirrhosis|Portal Hypertension|Varix, Esophageal
Interventions: DRUG: Carvedilol|OTHER: MRI scan|PROCEDURE: Hepatic Venous Pressure Gradient (HVPG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Cytochrome P450 Genotyping and Clinical Outcomes in Patients With Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Psychotic Disorder Not Otherwise Specified|Severe Bipolar Disorder With Psychotic Features
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Neural Basis of Communication in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Social Cognition|Neuropsychology|Psychological Therory|Theory of Mind
Interventions: OTHER: cognitive evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome
Status: UNKNOWN
Conditions: Rett Syndrome
Interventions: DRUG: Rett-T|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies
Status: RECRUITING
Conditions: Advanced Solid Malignancies
Interventions: DRUG: CFI-402411|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Four Orthodontic Bracket Prescriptions in Arch Width and Torque
Status: COMPLETED
Conditions: Dental Arch Relationship Anomaly
Interventions: DEVICE: Mini-Taurus® (Rocky Mountain©) Brackets|DEVICE: Smart Clip® SL3 High Torque (3M Unitek©)|DEVICE: Tip-Edge Plus® (TP Orthodontics©)|DEVICE: Victory® (3M Unitek©)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel With or Without Trastuzumab Following Peripheral Stem Cell Transplantation in Treating Patients With Refractory Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ZIMBA: Clinical Trial in Paediatric Obesity
Status: COMPLETED
Conditions: Obesity, Childhood|Insulin Resistance|Zinc Deficiency|Inositol
Interventions: DIETARY_SUPPLEMENT: Zinc|DRUG: Placebos|DRUG: Myoinositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Targeted Therapy Combined Chemotherapy in Advanced EGFR Positive NSCLC Patients
Status: COMPLETED
Conditions: Non-small-lung-cell Cancer|NSCLC|EGFR Gene Mutation
Interventions: DRUG: EGFR-TKI|DRUG: EGFR-TKI combined with chemotherapy (pemetrexed plus carboplatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eliciting Informed Goals of Care in Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Goals of Care|Patient Preference|End of Life
Interventions: OTHER: GOCD Tool|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Acupuncture on Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: OTHER: Acupuncture|DRUG: Ondansetron|DRUG: Physiological saline solution|OTHER: Sham acupuncture|DRUG: Ondansetron|OTHER: Acupuncture at P6 point|DRUG: Physiological saline solution|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effect of ASP1941 on Cardiac Repolarization in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Cardiac Repolarization
Interventions: DRUG: Placebo|DRUG: ASP1941|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of the RD-X19 Treatment Device in Individuals With Mild to Moderate COVID-19
Status: COMPLETED
Conditions: COVID19
Interventions: DEVICE: RD-X19|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Pectoral Nerve I and II Blocks in Multimodal Analgesia for Breast Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Pectoral nerve I and II block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
Status: RECRUITING
Conditions: CVA (Cerebrovascular Accident)|Stroke|Upper Extremity Paresis
Interventions: BEHAVIORAL: Grade 1 CI Therapy +Sensory Components
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Meditation During Radiotherapy.
Status: COMPLETED
Conditions: Quality of Life|Relaxation During Radiation Therapy|Cancer|Radiation Toxicity
Interventions: BEHAVIORAL: Meditation|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Coffee in Hemodialysis and Headache
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: DIETARY_SUPPLEMENT: Coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: aspirin and ketamine|DRUG: Nurtec (Rimegepant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Valsartan Plus Amlodipine and Valsartan Alone in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan/amlodipine 80/5 mg|DRUG: Valsartan 80 mg|DRUG: Valsartan 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stepwise for the Treatment of Lateral Incisional Hernias
Status: COMPLETED
Conditions: Incisional Hernia|Abdominal Wall Defect|Abdominal Wall Hernia|Hernia
Interventions: OTHER: Surgical Technique (lateral retromuscular preperitoneal)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Electromagnetic Therapy on Patients With Chronic Rhinosinusitis.
Status: COMPLETED
Conditions: Magnetic Therapy|Rhinosinusitis|Headache|Fatigue
Interventions: DEVICE: Pulsed electromagnetic field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Preventive Treatment Versus Scheduled Screening and Treatment of Malaria in Pregnancy
Status: COMPLETED
Conditions: Malaria|Pregnancy|Anaemia
Interventions: DRUG: Intermittent screening and treatment of malaria in pregnancy (IST)|DRUG: SP-IPTp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Journey of Transformation Curriculum for Native American Youth
Status: RECRUITING
Conditions: Alcohol Drinking|Tobacco Use|Substance Use|Sexual Behavior
Interventions: BEHAVIORAL: Journey of Transformation-Native Youth Health Leadership Program curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: All Ligaments Left In Knee Arthroplasty Trial
Status: UNKNOWN
Conditions: Primary Osteoarthritis of Knee Nos
Interventions: PROCEDURE: Vanguard XP Bi-cruciate Retaining Knee Replacement System|PROCEDURE: Vanguard CR Single Cruciate Retaining Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: CSF1R-related Leukoencephalopathy|ALSP|POLD|Hematopoietic Stem Cell Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cervical Spondylotic Myelopathy Surgical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Spondylosis With Myelopathy
Interventions: PROCEDURE: Ventral (Front) decompression with Fusion|PROCEDURE: Dorsal (Back) Decompression with Fusion|PROCEDURE: Dorsal (back) Laminoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1-1-8 Wash-in for Sevoflurane Low Flow Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: 1-1-8 wash-in|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RIBOGENE: Optimisation of Riboflavin Status in Hypertensive Adults With a Genetic Predisposition to Elevated Blood Pressure
Status: UNKNOWN
Conditions: Participants With the MTHFR 677TT Genotype
Interventions: DIETARY_SUPPLEMENT: Placebo comparator|DIETARY_SUPPLEMENT: 1.6mg riboflavin (Vitamin B2)|DIETARY_SUPPLEMENT: 10mg riboflavin (Vitamin B2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PROM Collected Via a Smartphone App Versus a Touch Screen Solution Among Patients With Inflammatory Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Axial Spondyloarthritis
Interventions: OTHER: PROM registration via the DANBIO App on a smartphone|OTHER: PROM registration via the touch screen solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With Glaucoma
Status: TERMINATED
Conditions: Glaucoma
Interventions: DRUG: bimatoprost ophthalmic solution formulation A|DRUG: timolol ophthalmic solution|DRUG: bimatoprost vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Insulin Resistance in Mood Disorders
Status: RECRUITING
Conditions: Major Depressive Disorder|Bipolar Disorder|Anhedonia|Intranasal Insulin
Interventions: DRUG: Humulin R|DRUG: Diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HeadStART: Evaluating the Effectiveness of Community ART Delivery for People Newly Diagnosed With HIV
Status: RECRUITING
Conditions: HIV Infections|Hiv
Interventions: OTHER: Community Antiretroviral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Candesartan for Migraine Prevention:
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine
Interventions: DRUG: Candesartan Oral Tablet 8 mg|DRUG: Candesartan Oral Tablet 16 mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Tropicamide 0.5% vs Tropicamide 1% on Intraocular Pressure of Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Type 1 Diabetes Mellitus
Interventions: DRUG: Tropicamide Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Status: COMPLETED
Conditions: Neonatal Hypoxia and Asphyxia
Interventions: PROCEDURE: Cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CoQ10 and Prednisone in Non-Ambulatory DMD
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Prednisone|DIETARY_SUPPLEMENT: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of TAK-659 in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: TAK-659
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: Carboxymethylcellulose and Glycerin based artificial tear|DRUG: Carboxymethylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome
Status: WITHDRAWN
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: DRUG: Cemdisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT