pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma|Urothelial Carcinoma|Renal Cell Carcinoma|Non-small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Colorectal Carcinoma
Interventions: DRUG: RC198 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients
Status: RECRUITING
Conditions: Polymyxin B|Ventilator-associated Pneumonia|Multidrug Resistant Bacterial Infection|Pharmacogenomic Drug Interaction
Interventions: DRUG: nebulized polymyxin B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabidiol and Management of Endometriosis Pain
Status: RECRUITING
Conditions: Endometriosis|CBD|Pelvic Pain
Interventions: DRUG: Cannabidiol (CBD) Extract|DRUG: Norethindrone Acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stop Exogenous Allergic Alveolitis (EAA) in Childhood
Status: SUSPENDED
Conditions: Allergic Alveolitis
Interventions: DRUG: Placebo|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DEVICE: rTMS Active 20Hz|DEVICE: rTMS Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Predictive Value of the Sperm Chromatin Dispersion Test, Halosperm®, Before and After Sperm Preparation for Clinical Pregnancy in Cases of Unexplained Infertility Treated With Intra-uterine Insemination (First Cycle) and Ovulation Induction With Clomiphene Citrate.
Status: COMPLETED
Conditions: Unexplained Infertility
Interventions: OTHER: Sperm Chromatin Dispersion Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NWT-03 and Brain Function
Status: COMPLETED
Conditions: Brain Vascular Function|Cognition
Interventions: DIETARY_SUPPLEMENT: An egg-protein hydrolysate (NWT-03)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Status: RECRUITING
Conditions: Bone Diseases, Infectious|Musculoskeletal Diseases|Joint Diseases|Osteoarthritis|ACL Tear|Cartilage Degeneration
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Immunogenicity Study of Homologous Ad26 Mosaic Vector Vaccine Regimens or Heterologous Ad26 Mosaic and MVA Mosaic Vector Vaccine Regimens With Glycoprotein 140 (gp140) for Human Immunodeficiency Virus (HIV) Prevention
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.Mos.HIV|BIOLOGICAL: MVA-Mosaic|BIOLOGICAL: gp140 DP Low-dose|BIOLOGICAL: gp140 DP High-dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biting Force and Chewing Efficiency of Complete Dentures.
Status: COMPLETED
Conditions: Biting|Chewing Problem
Interventions: OTHER: conventional complete denture|OTHER: CADCAM 3D printed denture|OTHER: CAD/CAM milled denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EDUCATE: The MEDTRONIC Endeavor Drug Eluting Stenting: Understanding Care, Antiplatelet Agents and Thrombotic Events
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Placebo Arm|DRUG: Thienopyridine Therapy|DEVICE: Surveillance Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Pain Management Intervention Preparatory to a Future Pragmatic Trial, ASCENT Study
Status: COMPLETED
Conditions: Chronic Leukemia|Hematopoietic and Lymphoid System Neoplasm|Lymphoma|Malignant Solid Neoplasm|Multiple Myeloma
Interventions: PROCEDURE: Acupuncture Therapy|BEHAVIORAL: Cancer Pain Management|BEHAVIORAL: Cognitive Behavior Therapy|PROCEDURE: Discussion|OTHER: Educational Intervention|OTHER: Exercise|OTHER: Interview|PROCEDURE: Massage Therapy|BEHAVIORAL: Mindfulness Relaxation|PROCEDURE: Pain Therapy|OTHER: Palliative Therapy|BEHAVIORAL: Patient Navigation|OTHER: Referral|PROCEDURE: Spiritual Therapy|PROCEDURE: Spiritual Care Referral|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fast Assay for Pathogen Identification - Quasi-Experimental Intervention Study
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Bacteremia
Interventions: DIAGNOSTIC_TEST: PathoRobot/ Patho-Doc Test result
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Open Label Phase I/II Clinical Trial to Evaluate CPI-613 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Cancer|Metastatic Cancer|Lymphoma|Solid Tumors|Advanced Malignancies
Interventions: DRUG: CPI-613
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers to Detect Endocrine Therapy Resistance
Status: RECRUITING
Conditions: Metastatic Cancer|Breast Cancer|Lobular Breast Carcinoma
Interventions: DRUG: 18F-fluorofuranylnorprogesterone|DEVICE: Liquid Biopsy|DEVICE: Positron Emission Tomography/Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: tDCS for Increasing Exercise Adherence in Depressed Individuals
Status: COMPLETED
Conditions: Depression|Physical Activity
Interventions: OTHER: tDCS|OTHER: Sham tDCS|BEHAVIORAL: Aerobic Exercise (AE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli Sprout Extract in Treating Patients With Transitional Cell Bladder Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Recurrent Bladder Cancer|Stage 0 Bladder Cancer|Stage I Bladder Cancer|Stage II Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: DRUG: broccoli sprout extract|OTHER: laboratory biomarker analysis|OTHER: Mango Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate Safety and Efficacy of Abiraterone in Participants With Prostate Cancer Who Have Received Docetaxel
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0215-0384 Administered to Subjects With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC0215-0384|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Acceptability of Nastent™ in Snoring and Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Snoring|Obstructive Sleep Apnea
Interventions: DEVICE: nastent™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CN-105 in Subject With Acute Supratentorial Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Acetyl-Valine-Serine-Arginine-Arginine-Arginine-NH2 (Ac-VSRRR- NH2).|DRUG: 0.9% Sodium-chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Performance of Polyethylene Fiber Reinforced Resin Composite Restorations (Wall Papering Technique) Versus Bulk Fill Resin Composite Restorations in Endodontically Treated Teeth Will be Evaluated Using Modified USPHS Criteria.
Status: COMPLETED
Conditions: Dental Restoration Failure
Interventions: OTHER: X-tra base & GrandioSO reinforced by Ribbond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of the Thoracolumbar Spine Fractures.
Status: UNKNOWN
Conditions: Spinal Fracture|Traumatic Fracture
Interventions: PROCEDURE: Conventional open surgery|PROCEDURE: Minimally invasive percutaneous surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance After Induction Chemotherapy in Elderly Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (Squamous or Non Squamous)
Interventions: DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Induction chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TERPS Trial for de Novo Oligometastic Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Oligometastatic Disease
Interventions: RADIATION: Prostate radiation (XRT)|DRUG: Systemic Therapy|RADIATION: Stereotactic ablative radiation therapy (SABR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight
Status: COMPLETED
Conditions: Type 2 Diabetes|Overweight|Obesity
Interventions: DRUG: Tirzepatide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Cannabidivarin|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Coronary Endothelial Function in Diabetic Patients With Acute Coronary Syndrome Using 15O-water Positron Emission Tomography
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: OTHER: Coronary endothelial function measurements by quantitative method (TEP at 15O-H2O)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Postoperative Quality of Recovery After Combined Lumbar Plexus-Sciatic Nerve Block (LPB-SNB)
Status: COMPLETED
Conditions: Lower Extremity Surgery
Interventions: DRUG: USG Guided Combined LPB-SNB with Isobaric Bupivacaine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GW572016 to Treat Recurrent Malignant Brain Tumors
Status: COMPLETED
Conditions: Glioma|Brain Tumor|Glioblastoma Multiforme|GBM|Gliosarcoma|GS
Interventions: DRUG: lapatinib ditosylate|PROCEDURE: Adjuvant therapy|PROCEDURE: Conventional surgery|PROCEDURE: Neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Untreated Mantle Cell Lymphoma
Interventions: DRUG: zanubrutinib and rituximab|DRUG: zanubrutinib and rituximab|DRUG: BEAM pretreatment|DRUG: zanubrutinib maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oligopin Supplementation and Bone Turnover Markers and Antioxidant Changes in Postmenopausal Osteopenic Women
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: Oligopin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Abciximab, Clopidogrel and Percutaneous Coronary Intervention in Acute Coronary Syndrome (ISAR-REACT-2)
Status: COMPLETED
Conditions: Coronary Disease|Angina, Unstable
Interventions: DRUG: Abciximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Status: COMPLETED
Conditions: Premature Ejaculation|Sexual Dysfunction
Interventions: DEVICE: Transcranial Radom Noise Stimulation|DRUG: Take Dapoxetine|COMBINATION_PRODUCT: Comparation EEG changes between Sham Group against tRNS and Dapoxetin participants|DIAGNOSTIC_TEST: Compare LPE EEG endophenotype between participants and healthy controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Subcutaneous Versus Intravenous MabThera (Rituximab) in Combination With Chemotherapy in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: rituximab [MabThera]|DRUG: rituximab [MabThera]|DRUG: rituximab [MabThera]
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPAL Study: A Study of Avastin (Bevacizumab) in Combination With FOLFOXIRI in Patients With Previously Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-FU|DRUG: bevacizumab [Avastin]|DRUG: irinotecan|DRUG: leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅱ Trial of Neoadjuvant Toripalimab Plus Platinum-doublet Chemotherapy in Locally Advanced NSCLC.
Status: ENROLLING_BY_INVITATION
Conditions: Locally Advanced NSCLC
Interventions: DRUG: Toripalimab combination with platinum-containing dual-drug chemotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Adductor Canal Block on Functional Recovery
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: PROCEDURE: Intrathecal morphine|PROCEDURE: Adductor Canal block|PROCEDURE: Peri-articular Infilteration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA Bacteremia
Status: TERMINATED
Conditions: Endocarditis, Bacterial|Infective Endocarditis
Interventions: DRUG: daptomycin|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
Status: COMPLETED
Conditions: Infection; Cesarean Section|Surgical Wound Infection|Endometritis
Interventions: OTHER: 80% inhaled oxygen via non-rebreather mask|OTHER: 30% inhaled oxygen via nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Safety of Extracorporeal Support With Hemoperfusion in Critical Patients With Multiorgan Dysfunction Syndrome by Septic Origin
Status: UNKNOWN
Conditions: Hemoperfusion|Multiorgan Failure|Sepsis
Interventions: PROCEDURE: Extracorporeal support with haemoperfusion|PROCEDURE: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD9833|DRUG: Midazolam|DRUG: Omeprazole|DRUG: Dabigatran Etexilate|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindbeacon Therapist Assisted Internet Delivered CBT for Depression
Status: WITHDRAWN
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Mindbeacon Therapist Guided, Internet Cognitive Behavioral Therapy for Depression|OTHER: Waitlist Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Endometrial Suturing on the Risk of Uterine Scar Defect
Status: COMPLETED
Conditions: Cesarean Wound Disruption
Interventions: PROCEDURE: Endometrial suturing|PROCEDURE: Non- endometrial suturing|DEVICE: Vaginal ultrasonography|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Niraparib/TTFields in GBM
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|GBM
Interventions: DRUG: Niraparib|DEVICE: Optune|PROCEDURE: Planned surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Leuprolide, Degarelix or Relugolix|RADIATION: Stereotactic body radiation therapy/radiosurgery (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors
Status: UNKNOWN
Conditions: B Cell Lymphoma|B Cell Leukemia|Myeloma|Hepatocellular Carcinoma|Pancreatic Carcinoma|Adenocarcinoma of Esophagogastric Junction
Interventions: GENETIC: CAR-CD19 T cell|GENETIC: CAR-BCMA T cell|GENETIC: CAR-GPC3 T cell|GENETIC: CAR-CLD18 T cell|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Versus Cognitive Behavioural Therapy on Cancer-related Fatigue
Status: UNKNOWN
Conditions: Fatigue|Mood|Maximal Oxygen Uptake
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Effect of Mobile Applications "My A:Care" and "Smart Coach" on the Lipid-lowering Treatment Adherence of Subjects With Dyslipidemia in Thailand
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: BEHAVIORAL: My A:care|BEHAVIORAL: Smart Coach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dabrafenib and Trametinib With Radiosurgery in Melanoma Brain Mets
Status: TERMINATED
Conditions: BRAFV600E Melanoma Patients
Interventions: DRUG: Dabrafenib|PROCEDURE: Gamma Knife Radiosurgery|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: GSK3511294 (Depemokimab)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Gonial Angle as a Predictive Marker of Mandibular Fossa Depth
Status: COMPLETED
Conditions: Dental Implants|Submandibular Fossa Depth|Gonial Angle|Cone-beam Computed Tomography|Panoramic Radiography
Interventions: DIAGNOSTIC_TEST: Gonial angle and submandibular fossa depth measurements from CBCT images
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mid-term Effect of a Novel Sit-to-stand Workplace (ACTIVE OFFICE) on Cognitive and Physiological Parameters
Status: COMPLETED
Conditions: Sedentary Lifestyle|Worksite
Interventions: OTHER: Workplace consisting of two height-adjustable desks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Resource Sparing Curative Radiotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck: The HYPNO Trial
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: RADIATION: External beam radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indirect Endovenous Systemic Ozone for New Coronavirus Disease (COVID19) in Non-intubated Patients
Status: UNKNOWN
Conditions: COVID
Interventions: OTHER: Systemic indirect endovenous ozone therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Immunomodulatory Treatment in Success of ICSI in Patients With Autoimmune Thyroiditis
Status: COMPLETED
Conditions: Infertility|Autoimmune Thyroiditis
Interventions: DRUG: Immunomodulatory|DRUG: Thyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Electric and Acoustic Hearing (EAS) in Children and Adults
Status: RECRUITING
Conditions: Cochlear Implant|Hearing Loss
Interventions: OTHER: Electric and acoustic stimulation (EAS) technology in the implanted ear(s)-this is the combination of a cochlear implant (CI) and hearing aid (HA) in the implanted ear(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Pressure Monitoring After Trauma or Hemorrhage
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)|Subarachnoid Hemorrhage (SAH)
Interventions: DEVICE: Non-invasive ICP measurement device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: PF-07081532
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Appendectomy Versus Conservative Treatment for Uncomplicated Acute Appendicitis
Status: COMPLETED
Conditions: Acute Appendicitis|Appendicitis Recurrent|Appendectomy|Antibiotic Therapy
Interventions: PROCEDURE: Laparoscopic or Open appendectomy|DRUG: Antibiotic-first therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Glioblastoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Cancer|Solid Neoplasm|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic and Therapeutic Effects of American and Korean Red Ginseng in the Treatment of Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus Type 2
Interventions: DIETARY_SUPPLEMENT: American Ginseng (Panax quinquefolius L.) and Korean Red Ginseng (steamed Panax C.A. Meyer)|DIETARY_SUPPLEMENT: American Ginseng (Panax quinquefolius L.)|DIETARY_SUPPLEMENT: Wheat Bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Versus Topical Agents on Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: OTHER: Exercise|OTHER: Exercise&Topical Agent|OTHER: Topical Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without Low-dose, Short Course Sunitinib in Refractory Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumors|Breast Cancer|Non-small Cell Lung Cancer|Prostate Cancer|Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Subconjunctival Injection of Bevacizumab in the Treatment of Corneal Neovasculization
Status: COMPLETED
Conditions: Lipid Keratopathy|Penetrating Keratoplasty|Herpetic Keratopathy|Rosacea
Interventions: DRUG: subconjunctival injection of bevacizumab ( 1.25 to 2.50 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 50-59 Years of Age, Including Adults at Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease, Compared to Older Adults 60 Years of Age and Above
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BI 1819479|DRUG: Placebo matching BI 1819479
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MAD in Cancer Patients: Safety of BMS-582664 in Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Tumors|Neoplasm Metastasis
Interventions: DRUG: Brivanib|DRUG: Brivanib|DRUG: Brivanib|DRUG: Brivanib|DRUG: Brivanib|DRUG: Brivanab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
Status: COMPLETED
Conditions: Photoaging|Wrinkle|Skin Laxity
Interventions: PROCEDURE: Fractional Ablative CO2 Laser|OTHER: Facial Cleanser|OTHER: Facial Moisturizer|OTHER: Sunscreen|OTHER: Basic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Erector Spinae Plane Block for Postoperative Analgesia for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: erector spinae plane block|DEVICE: Intravenous morphine patient controlled analgesia device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|Resectable Glioblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: PF-00477736 Is Being Studied In Advanced Solid Tumors In Combination With Chemotherapy With Gemcitabine
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: PF-00477736|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of AN-PEP Enzyme on Gluten Digestion
Status: COMPLETED
Conditions: Gluten Digestion
Interventions: DIETARY_SUPPLEMENT: AN-PEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Self-Efficacy, Resolving Inflammaging Allo HSCT Survivors in Personal Training
Status: COMPLETED
Conditions: Allogeneic HCT Survivors
Interventions: OTHER: 10 Weeks of Strength Trailing|OTHER: Group Nutrition Discussion: week 1, week 5 and week 10
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Multi-parametric and Bi-parametric Magnetic Resonance Imaging in Men With Suspicion of Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: DIAGNOSTIC_TEST: bi-parametric MRI|DIAGNOSTIC_TEST: multi-parametric MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Short-term Clinical Feasibility of the Provox XtraHMEs for Pulmonary Rehabilitation After Total Laryngectomy
Status: COMPLETED
Conditions: Total Laryngectomy
Interventions: DEVICE: Provox Xtra HME
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Exercise Therapy Interventions on the Performance and Injury Prevention in Competitive Sports
Status: RECRUITING
Conditions: Strain of Fascia of Intrinsic Muscle of Foot (Disorder)|Elastography|Muscle Weakness
Interventions: DEVICE: Shear Wave Ultrasound Elastography|DEVICE: The 3-D Motion Analysis|DEVICE: Electromyographic|DIAGNOSTIC_TEST: Foot intrinsic muscle assessment and training device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Nexium|DRUG: Amolin|DRUG: Klaricid|DRUG: Flagyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Soft Contact Lenses in Symptomatic Patients
Status: COMPLETED
Conditions: Contact Lens Care
Interventions: DEVICE: OptiFree Multi-Purpose Disinfecting Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: RITUXIMAB + IMMUNOTHERAPY IN FOLLICULAR LYMPHOMA
Status: ACTIVE_NOT_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab|DRUG: Utomilumab|DRUG: Avelumab|DRUG: PF04518600
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Instrumentation Time Using Pediatric Rotary Versus Hand (Flare) File Systems
Status: NOT_YET_RECRUITING
Conditions: Instrumentation Time
Interventions: PROCEDURE: Pediatric rotary files|PROCEDURE: Manual flare files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING)
Status: UNKNOWN
Conditions: Moderate to Severe Dry Eye
Interventions: DRUG: Cyclosporine 0.1% (Ikervis®) eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electro Magnetic Fields (PEMF) Treatment in Patients With Treatment-Resistant Major Depression in Ongoing Pharmacological Treatment of Depression
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Pulsating Electro-Magnetic Fields|DEVICE: Pulsating Electro-Magnetic Fields sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Effect of Conbercept Intravitreal Injection at the Conclusion of Cataract Surgery for Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema|Diabetic Retinopathy|Cataract Diabetic
Interventions: PROCEDURE: Conbercept intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Aphasia|Stroke
Interventions: DRUG: memantine|PROCEDURE: constraint-induced language therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Lithotripsy Using Fluoroscopic Versus Ultrasonic Localization
Status: COMPLETED
Conditions: Stone, Kidney|Child, Only
Interventions: PROCEDURE: ultrasonic focus Shock wave lithotripsy|PROCEDURE: fluoroscopic focus Shock wave lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With Cold Agglutinin Disease (CAD)
Status: SUSPENDED
Conditions: Cold Agglutinin Disease
Interventions: DRUG: Pegcetacoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib lead-in Followed by Venetoclax Plus Ibrutinib in Patients With RR CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Bronchodilator Effect of Formoterol Fumarate Used in Combination With Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P06476 AM2)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Formoterol Fumarate DPI|DRUG: Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) without spacer|DRUG: Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) with spacer|DRUG: Placebo MDI with spacer|DRUG: Placebo MDI without spacer|DRUG: Mometasone Furoate DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Safety, Tolerability, Pharmacokinetics, and Recommended Phase 2 Dose (RP2D) of Intravenous ABBV-184 in Adult Participants With Previously Treated Cancers
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)|Non Small Cell Lung Cancer|Cancer
Interventions: DRUG: ABBV-184
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of Pediatric Air Test as a Non-invasive Atelectasis Diagnostic Tool
Status: COMPLETED
Conditions: Lung Collapse|Lung Diseases|Atelectasis|Atelectasis Without Respiratory Distress Syndrome|Atelectases, Resorption|Air Test|Pediatric Disorder
Interventions: DIAGNOSTIC_TEST: Air test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Moderate Renal Impairment
Interventions: BIOLOGICAL: CSL_112|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Perineural Catheter Depth for the Continuous Popliteal Nerve Block Using Ultrasound Guidance and Dermabond
Status: COMPLETED
Conditions: Neuromuscular Inhibition
Interventions: PROCEDURE: 1 cm|PROCEDURE: 5 cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia
Status: COMPLETED
Conditions: Phobic Disorders
Interventions: BEHAVIORAL: Individual Cognitive Behavioral Therapy (CBT)|DRUG: D-Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dietary Fiber as Prebiotics on Intestinal Microbiota in Obese Thai Children
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Intravenous Lidocaine Infusion for Patients Undergoing Laparoscopic and Open Pancreatectomies
Status: COMPLETED
Conditions: Pancreatectomy
Interventions: DRUG: Lidocaine|DRUG: Placebo D5W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Delavirdine mesylate|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation of Abdominal Muscles for Bowel Management in People With Spinal Cord Injury
Status: RECRUITING
Conditions: Neurogenic Bowel
Interventions: DEVICE: abdominal functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bleeding in Knee Arthroplasty After Preconditioning With Sevoflurane
Status: COMPLETED
Conditions: Blood Loss, Surgical|Blood Transfusion
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application
Status: COMPLETED
Conditions: Hemodynamic Response|Skull Pins Application
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl|DRUG: 0.9% normal saline|DEVICE: Skull pins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat
Status: COMPLETED
Conditions: Major Depressive Disorder|Generalized Anxiety Disorder
Interventions: DRUG: seroquel xr|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: idarubicin|DRUG: lomustine|DRUG: melphalan|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Ileo Neo Rectal Anastomosis Compared to the Ileo Pouch Anal Anastomosis for Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative|Surgery
Interventions: PROCEDURE: Ileal Neo Rectal Anastomosis|PROCEDURE: Ileal Pouch Anal Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Toric Versus Non-toric Intraocular Lenses in Phacoemulsification Cataract Surgery
Status: UNKNOWN
Conditions: Cataract|Astigmatism
Interventions: DEVICE: Phacoemulsfication cataract surgery and intra-ocular lens implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: Omegaven|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Comparative Clinical Study to Investigate the Use of the NON CONTACT TONO/PACHYMETER NT-530P
Status: COMPLETED
Conditions: IOP Ranges(mmHg): 7 to 16, >16 to <23, and 23 or More
Interventions: DEVICE: NT-530P
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: RGN-259|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Endpoint Bioequivalence Study of Adapalene Gel 0.1%
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene 0.1% Gel|DRUG: Differin 0.1% Topical Gel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine for Hypotension in Cesarean Section
Status: COMPLETED
Conditions: Hypotension|Cesarean Section
Interventions: DRUG: Norepinephrine|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ghrelin in Patients With a Rare Disease Associated With Intellectual Disability, and Hyperphagia, and/or Overweight, and/or Obesity
Status: RECRUITING
Conditions: Angelman Syndrome|Smith-Magenis Syndrome|X Fragile Syndrome|Epilepsy|Prader-Willi Syndrome
Interventions: BIOLOGICAL: acylated and unacylated ghrelin dosages
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beta-glucan and Immune Response to Influenza Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Aging
Interventions: BIOLOGICAL: Influenza Vaccine|DIETARY_SUPPLEMENT: Beta-glucan|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER