pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Changes of Biomarkers in Response to Training and Antioxidant Treatment
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Vitamin C, Vitamin E|DIETARY_SUPPLEMENT: Antioxidant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: non-pharmacological treatment strategy|PROCEDURE: pharmacological treatment strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefit Provided by Acupuncture During a Surgery of Deep Brain Stimulation
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Electroacupuncture|DRUG: Local Anesthesia (lidocaine hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TRIO Bladder: A Study of Durvalumab Plus Tremelimumab Followed by Concurrent Durvalumab Plus Bladder Radiation in Muscle-Invasive Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab|RADIATION: Bladder radiation|DRUG: Intravesicular Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiotropic Viruses in Cardiac Surgery Patients Without Clinical Evidence of Myocarditis or Myocarditic Sequelae
Status: TERMINATED
Conditions: Myocarditis
Interventions: PROCEDURE: Myocardial biopsies with TRU CUT 14 Gauge needle|PROCEDURE: Endomyocardial biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Sabizabulin|DRUG: Exemestane monotherapy, exemestane plus everolimus, or selective estrogen receptor modulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Aflibercept Injection to Treat Blood Vessel Growth Over the Cornea
Status: TERMINATED
Conditions: Corneal Neovascularization
Interventions: DRUG: Subconjunctival aflibercept|OTHER: Placebo: Standard of care only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalating Study of CCI15106 Inhalation Capsules in Healthy Subjects and Moderate Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: CCI15106 7.5 mg capsule|DRUG: Placebo|DRUG: Placebo-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Traditional Dietary Advice Versus Reassurance-alone in Postprandial Functional Dyspepsia
Status: RECRUITING
Conditions: Dyspepsia|Functional Gastrointestinal Disorders
Interventions: OTHER: Reassurance-alone|BEHAVIORAL: Traditional dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Radiosurgery for Asymptomatic Oligo Brain Metastasis
Status: UNKNOWN
Conditions: Nonsmall Cell Lung Cancer
Interventions: RADIATION: Radiosurgery|RADIATION: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Changes in Endothelial Function in Germ Cell Tumor Patients Treated With Cisplatin and Untreated Germ Cell Tumor Controls
Status: ACTIVE_NOT_RECRUITING
Conditions: Germ Cell Cancer
Interventions: OTHER: Endo-PAT2000 testing|OTHER: Endo-PAT2000 testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Toxicity/Benefit Ratio Optimization of Chemotherapy in Colorectal Cancer (CRC) Patients by Determination of Individual Genotypic Determinants
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: irinotecan|DRUG: 5 fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Fish Oil Based Intravenous Fat Emulsions on the Epidermal Barrier Function
Status: TERMINATED
Conditions: Intestinal Diseases
Interventions: DRUG: soybean oil (SO)-based IVFE (Medialipide)|DRUG: fish oil (FO)-containing IVFE (Lipidem)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Intrauterine Platelet-Rich Plasma Instillation And Endometrial Scratching for Thinned Endometrium
Status: UNKNOWN
Conditions: Infertility Due to Nonimplantation
Interventions: BIOLOGICAL: platlet rich plasma|PROCEDURE: endometrial scratch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Depression Relapse With Mindfulness-Based Cognitive Therapy
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Mindfulness based cognitive therapy (MBCT)|DRUG: Antidepressants|DRUG: Placebo plus clinical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of Faldaprevir Effect on Pharmacokinetics of Raltegravir
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Raltegravir|DRUG: Raltegravir|DRUG: Faldaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasm Female
Interventions: PROCEDURE: Neo-adjuvant Chemotherapy|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Analgesia-Monitors in Tracing Unconscious Pain Sensations
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Analgesia monitor (PhysioDoloris®)|DEVICE: Analgesia monitor (SPI®)|DEVICE: Analgesia monitor (AlgiScan®)|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CO Monitoring for Tobacco Cessation in Quitlines
Status: RECRUITING
Conditions: Tobacco Dependence
Interventions: COMBINATION_PRODUCT: Quitline Treatment as Usual (TAU)|COMBINATION_PRODUCT: Remote Carbon Monoxide (CO) Monitoring|COMBINATION_PRODUCT: Incentivized Remote CO Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome|Natural Killer Cell Lymphoblastic Leukemia/Lymphoma
Interventions: BIOLOGICAL: Single Umbilical Cord Blood Unit Transplant|BIOLOGICAL: Double Umbilical Cord Blood Unit Transplant|RADIATION: Total Body Irradiation|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Cyclosporine A|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nutritional Products in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: Standard ONS|OTHER: Diabetes specific ONS 1|OTHER: Diabetes specific ONS 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Status: RECRUITING
Conditions: Knee; Injury, Meniscus (Lateral) (Medial)|Meniscus Tear|Meniscus Lesion|Meniscus; Degeneration|Meniscus; Laceration|Meniscus Injury, Tibial|Knee Injuries|Knee Pain Swelling|Arthralgia
Interventions: DRUG: SF-MSC-EX|DRUG: SF-MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Trimer 4571 Therapeutic Vaccination in Adults Living With HIV on Suppressive Antiretroviral Therapy
Status: RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: Trimer 4571 vaccine 100mcg with 500mcg alum adjuvant|BIOLOGICAL: Placebo control for Trimer 4571 vaccine 100mcg with 500mcg alum adjuvant|BIOLOGICAL: Trimer 4571 vaccine 500mcg with 500mcg alum adjuvant|BIOLOGICAL: Placebo control for Trimer 4571 vaccine 500mcg with 500mcg alum adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Exogenous Ketone Ester Administration in Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain Control in Total Shoulder Arthroplasty
Status: RECRUITING
Conditions: Total Shoulder Arthroplasty
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Bevacizumab|DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
Status: RECRUITING
Conditions: Diabetic Neuropathies
Interventions: DRUG: Fish Oil Concentrate, 1000 Mg Oral Capsule|DRUG: Salsalate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laryngomalacia Study
Status: WITHDRAWN
Conditions: Laryngomalacia
Interventions: DRUG: Omeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Satisfaction of Hospitalized Diabetic Patients Using a Continuous Glucose Monitoring System
Status: TERMINATED
Conditions: Insulin-Dependent Diabetes
Interventions: DEVICE: FreeStyle Libre™ system|PROCEDURE: Finger prick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Positive End Espiratory Pressure Trial in Coronavirus Disease 19 Treated With Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: OTHER: PEEP Standard Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist
Status: TERMINATED
Conditions: Liver Cirrhoses
Interventions: OTHER: Trans-thoracic ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Antibiotic Treatment of Patients With Chronic Obstructive Lung Disease (COLD)
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia
Status: RECRUITING
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Modified transplantation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: Placebo|DRUG: Non-steroidal anti-inflammatory drugs (NSAIDs)|DRUG: methotrexate|DRUG: corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention av Autoimmunitet Med Laktobaciller
Status: RECRUITING
Conditions: Celiac Disease in Children|Type 1 Diabetes|Thyroid
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of rBet v1 SLIT Tablets
Status: COMPLETED
Conditions: Birch Pollen-Related Rhinoconjunctivitis|Rhinitis, Allergic, Seasonal
Interventions: BIOLOGICAL: rBet v 1|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Fasting & Exercise in Pts With HR+ MBC
Status: COMPLETED
Conditions: Breast Cancer|Metastatic Breast Cancer
Interventions: BEHAVIORAL: Prolonged Nightly Fasting|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HPV Testing for Cervical Cancer Screening Study
Status: COMPLETED
Conditions: Cervical Cancer Screening
Interventions: PROCEDURE: Cervical cancer screening undertaken by HPV testing as a single primary screening test with cytology triage of women who are HPV positive|PROCEDURE: Cervical cancer screening undertaken by HPV testing as a single primary screening test with cytology triage of women who are HPV positive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-Inferiority Trial of Acute HFT Versus nCPAP
Status: WITHDRAWN
Conditions: Mild-Moderate Obstructive Sleep Disordered Breathing
Interventions: DEVICE: High-Flow Therapy|DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer, Esophageal Cancer and Liver Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Esophageal Cancer|Liver Cancer
Interventions: BIOLOGICAL: neoantigen tumor vaccine with or without PD-1/L1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obturator Nerve Block With Femoral and Sciatic Block
Status: COMPLETED
Conditions: Nerve Block; Pain Medication
Interventions: PROCEDURE: Oburator Nerve block|PROCEDURE: Sham Injection in pectineus muscle.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interest of Late Images for the Assessment of Extensions in 18FGD PET-CT of Muscle-Invasive Bladder Cancers
Status: RECRUITING
Conditions: Muscle-Invasive Bladder Carcinoma|Bladder Cancer
Interventions: PROCEDURE: 18FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Bioequivalence (BE) and the Food Effect of TAK-438ASA Tablet
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-438ASA|DRUG: TAK-438|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With Methotrexate Versus Methotrexate Alone in Patients With RA
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: ENIA11|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia
Status: COMPLETED
Conditions: Obesity|Hypoglycemia|Surgery
Interventions: DIETARY_SUPPLEMENT: Oral Glucose tolerance test (OGGT)|DIETARY_SUPPLEMENT: Liquid mixed meal|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PRT Versus CBT on Chronic Non Specific LBP
Status: RECRUITING
Conditions: Chronic Non Specific Mechanical Low Back Pain
Interventions: OTHER: positional release technique|OTHER: cognitive behavioral therapy|OTHER: conventional therapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Somatropin Therapy In Children Born Preterm But Appropriate For Gestational Age
Status: COMPLETED
Conditions: Growth Hormone Therapy|Infant, Very Low Birth Weight
Interventions: DRUG: Somatropin|OTHER: Control Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Paragastric Neural Block Procedure on Postoperative Pain in Patients Who Underwent Sleeve Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Post Operative Pain
Interventions: OTHER: Paragastric neural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Growth Hormone (Somatropin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Success Rate of Cardiopulmonary Resuscitation in Patients Experiencing In-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest, Sudden|Cardiopulmonary Arrest|Cardiopulmonary Failure|In-hospital Cardiac Arrest
Interventions: PROCEDURE: CPR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Metformin on Reducing Lupus Flares
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: metformin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Clinical Response to Mitomycin-C in Hydrogel (TC-3) Administered Intravesically in NMIBC Patients
Status: COMPLETED
Conditions: Urinary Bladder Neoplasms|Urologic Neoplasms|Neoplasms|Urinary Bladder Diseases|Urologic Diseases
Interventions: DEVICE: 40 mg MMC in 40 mL TC-3.|DEVICE: 80 mg MMC in 40 mL TC-3.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Exparel Based ESP Blocks in Elective Posterior Spine Fusion
Status: NOT_YET_RECRUITING
Conditions: Spine Fusion|Anesthesia, Local
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury
Interventions: OTHER: BCTT|OTHER: Dynamic ExIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: D9319C00001- 1L OC Mono Global RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|OTHER: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Resistance Training in Acute Spinal Cord Injury
Status: TERMINATED
Conditions: Spinal Cord Injuries|Quadriplegia|Trauma, Nervous System|Paralysis|Spinal Cord Diseases
Interventions: OTHER: Progressive Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Adaptos®Ortho Wedge Bone Graft Substitute in High Tibial Osteotomy
Status: RECRUITING
Conditions: Knee Deformity
Interventions: DEVICE: Adaptos®Ortho Wedge (bone grafting surgery)|PROCEDURE: OWHTO without bone grafting|DEVICE: chronOS® Wedge (bone grafting surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: AG-920|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: POWERSforID: A Telehealth Weight Management System for Adults With Intellectual Disability
Status: COMPLETED
Conditions: Intellectual Disability|Weight Loss|Motivational Interviewing|Telehealth
Interventions: BEHAVIORAL: POWERSforID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of the MIND Diet on Oxidative Stress, Inflammation and Neurodegenerative Risk Biomarkers
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurodegeneration|Inflammation|Oxidative Stress|Diet, Healthy|Diet Habit|Nutrition, Healthy
Interventions: BEHAVIORAL: MIND diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Bimodal Stimulation Using Auditory and Vibrotactile Stimuli for the Mitigation of Tinnitus
Status: NOT_YET_RECRUITING
Conditions: Tinnitus
Interventions: DEVICE: Neosensory Wristband|OTHER: Tones only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of ANS-6637 to Reduce Drug Craving and Harm in People With Opioid Use Disorder
Status: WITHDRAWN
Conditions: Opioid-use Disorder
Interventions: DRUG: ANS-6637|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunochemotherapy in PD-L1-negative LACC
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Locally Advanced Cervical Cancer|PD-L1 Negative|Neoadjuvant Chemoimmunotherapy
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel-albumin|DRUG: Cisplatin|PROCEDURE: radical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Amplimexon Plus Taxotere in Metastatic Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Imexon + docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Concentration of Adalimumab as a Predictive Factor of Clinical Outcomes in Rheumatoid Arthritis (AFORA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effect of Bezafibrate on the Level of Very Long Chain Fatty Acids (VLCFA) in X-linked Adrenoleukodystrophy (X-ALD)
Status: COMPLETED
Conditions: X-linked Adrenoleukodystrophy|Adrenomyeloneuropathy
Interventions: DRUG: Bezafibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Electrocochleography During Cochlear Implantation of the Neuro Zti.
Status: WITHDRAWN
Conditions: Cochlear Hearing Loss|Cochlear Trauma
Interventions: DEVICE: Neuro Cochlear Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Chemoimmunotherapy With R+B+M Followed by R in Elderly Patients Advanced Stage Untreated Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: Rituximab, Mitoxantrone, Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy or Intensity Modulated Radiation/Proton Therapy in Treating Patients With Recurrent Head and Neck Cancer
Status: RECRUITING
Conditions: Recurrent Head and Neck Carcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: Proton Radiation|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Hetrombopag Olamine in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hetrombopag Olamine Tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Tolerability of Abrupt Discontinuation of Saredutant in Patients With Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Saredutant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraarterial Nitroglycerin Versus Nicardipine and Radial Artery Occlusion
Status: COMPLETED
Conditions: Radial Artery Injury at Wrist and Hand Level|Occlusion of Artery|Vasodilation
Interventions: DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Observational Studies of the Application of Bevacizumab in HER2-negative Breast Cancer Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Bevacizumab|Neoadjuvant Chemotherapy|Molecular Targeted Therapy
Interventions: DRUG: bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Focal Muscular Vibration in Patients With Severe Acquired Brain Injury
Status: RECRUITING
Conditions: Brain Injuries|Spasticity, Muscle
Interventions: DEVICE: Focal Muscular Vibration using the EVM EVO medical device (Endomedica, Italy)|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smartphone-based Ecological Momentary Intervention for Suicide Prevention: a Randomised Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Suicide
Interventions: DEVICE: SmartSafe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Study of GlaxoSmithKline (GSK) Biologicals' Candidate Influenza Vaccine GSK2321138A in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent seasonal influenza vaccine(Flu D-QIV) GSK2321138A|BIOLOGICAL: Havrix Junior|BIOLOGICAL: Prevenar 13|BIOLOGICAL: Varivax/ProVarivax|BIOLOGICAL: Varilrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanisms and Management of Infant Dysphagia
Status: COMPLETED
Conditions: Dysphagia|Airway Aspiration|Airway Penetration
Interventions: DIAGNOSTIC_TEST: Combined testing (diagnostic VFSS + research HRM) + Parent Preferred Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: propofol|DRUG: midazolam|DRUG: alfentanil|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Cannulation Using Vein Display Instrument and Without Using Vein Display Instrument in Pediatric Patients
Status: COMPLETED
Conditions: Difficult Vein Access
Interventions: DEVICE: Vein Display Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internal Biodegradable Stent Versus Non-Stent in Patients at High-Risk of Developing Fistula After Pancreatoduodenectomy
Status: RECRUITING
Conditions: Pancreatoduodenectomy|Clinically Relevant Postoperative Pancreatic Fistula|Internal Biodegradable Pancreatic Stent
Interventions: DEVICE: Biodegradable Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxocobalamin Approach for Reducing of Calprotectin With Butyrate for Ulcerative Colitis Remission
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Hydroxocobalamin with Butyrate|DRUG: Placebo with Butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Use of Virtual Reality in Rehabilitation in Patients After Vestibular Schwannoma Surgery.
Status: RECRUITING
Conditions: Acute Peripheral Vestibulopathy Following Surgical Procedure
Interventions: PROCEDURE: Prehabituation|PROCEDURE: 3D optokinetic stimulation in virtual reality space|PROCEDURE: Vestibular training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo and Active Controlled Study to Assess Efficacy and Tolerability of Aspirin Plus Pseudoephedrine
Status: COMPLETED
Conditions: Common Cold|Pharyngitis
Interventions: DRUG: Acetylsalicylic Acid (Aspirin Complex, BAYE4465) + Pseudoephedrine|DRUG: Acetylsalicylic Acid (Aspirin, BAYE4465)|DRUG: Pseudoephedrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Effects and Palatability of Sisunatovir in Healthy Adult Participants
Status: COMPLETED
Conditions: Respiratory Syncytial Viruses
Interventions: DRUG: sisunatovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized, Controlled Evaluation of a Virtual Human Patient for Provider Training in Motivational Interviewing
Status: COMPLETED
Conditions: Motivational Interviewing
Interventions: OTHER: Virtual Standardized Patient|OTHER: Academic Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preventing Fetal Body and Brain Size Reduction in Low-income Smoking Mothers: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Fetal Body Size|Fetal Brain Size
Interventions: DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: Drain|PROCEDURE: Progressive Tension Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History
Status: COMPLETED
Conditions: Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Benralizumab Arm A|DRUG: Benralizumab Arm B|DRUG: Benralizumab Arm C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Consolidation Pembrolizumab After Concurrent Chemotherapy and Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Community-level HIV/STD Prevention Intervention in Promoting Safer Sexual Behaviors in High-risk Populations
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Community Popular Opinion Leader (C-POL)|BEHAVIORAL: HIV/STD educational materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis|Erector Spinae Plane Block
Interventions: PROCEDURE: ESPB|PROCEDURE: Local infiltration by the surgeon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of New Injection Molded Flocked Nasopharyngeal Swabs in Response to the COVID-19 Pandemic
Status: COMPLETED
Conditions: COVID19
Interventions: DEVICE: Control swab|DEVICE: Prototype swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Erector Spinae Plane Block Method Used in Pain Management in Heart Surgery on Vascular Diameters
Status: COMPLETED
Conditions: Coronary Artery Disease|Erector Spinae Plane Block|Bypass Extremity Graft
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Parietaria Judaica
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Depigoid Parietaria judaica 1000DPP/ml|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Itopride HCI 50 mg|DRUG: Itopride HCI 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability of Andago V2.0 in Gait Rehabilitation of Stroke Patients
Status: COMPLETED
Conditions: Brain Ischemia|Intracranial Haemorrhage
Interventions: DEVICE: Andago V2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine Effects on Tetrahydrocannabinol
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Delta-9-THC|DRUG: N-acetylcysteine|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Group Cognitive Behavioural Family Intervention (CBFI) for People With Schizophrenia and Their Families
Status: WITHDRAWN
Conditions: Schizophrenia|Psychosis
Interventions: BEHAVIORAL: Group Cognitive behavioural family intervention (CBFI)|BEHAVIORAL: Usual group psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caudal Anesthesia Versus Local Anesthesia in Hypospadias
Status: RECRUITING
Conditions: Hypospadias|Hypospadias, Coronal|Caudal Anesthesia|Children
Interventions: DRUG: Caudal block anesthesia|DRUG: Dorsal penile block anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Using CP-751,871 In Patients With Stage IV Colorectal Cancer That Has Not Responded To Previous Anti-Cancer Treatments
Status: COMPLETED
Conditions: Colorectal Neoplasm
Interventions: BIOLOGICAL: CP-751, 871
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Injectable Medical Device to Treat Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: MM-II|DEVICE: DurolaneTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Digital Biofeedback System for Home-based Rehabilitation After Total Joint Replacement
Status: COMPLETED
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: DEVICE: Digital kinematic biofeedback system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis|Neurofibromas
Interventions: DRUG: Gleevec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Metastatic Cancer|Sarcoma
Interventions: BIOLOGICAL: aerosol sargramostim|BIOLOGICAL: sargramostim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: mitomycin C|OTHER: flow cytometry|OTHER: immunological diagnostic method|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: multimodality therapy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic conventional surgery|RADIATION: intraoperative radiation therapy|RADIATION: selective external radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of HFNC on Exercise Capacity Compared to VM in COPD Patients Recovering From Acute Evacerbation
Status: UNKNOWN
Conditions: COPD
Interventions: DEVICE: high flow nasal cannula|DEVICE: Venturi mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorthalidone Compared to Hydrochlorothiazide on Endothelial Function
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Chlorthalidone 12.5 mg|DRUG: Hydrochlorothiazide 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Periodontitis by Conventional 4 Weekly Sections or Within 24 Hours
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: FMS full-mouth scaling|PROCEDURE: QS quadrant scaling|DRUG: FMS chlorhexidine rinse|DRUG: FMS placebo rinse|DRUG: FMS azithromycin tablets|DRUG: FMS placebo tablets|DRUG: QS azithromycin tablets|DRUG: QS placebo tablets|DRUG: QS chlorhexidine rinse|DRUG: QS placebo rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Menstrual Cup for VVF
Status: UNKNOWN
Conditions: Vaginal Fistula|Vesico Vaginal Fistula|Obstetric; Injury
Interventions: DEVICE: Menstrual Cup
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients
Status: UNKNOWN
Conditions: HIV-Associated Lipodystrophy Syndrome
Interventions: DRUG: nucleoside analogue sparing HAART regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia
Status: COMPLETED
Conditions: Severe Aplastic Anemia
Interventions: DRUG: ATG+Rapamune+cyclosporine|DRUG: ATG+cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of ASP1941 in Adults With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Bupivacaine With Bupivacaine in Ultrasonography Guided Fascia Iliaca Compartment Block in Adults
Status: UNKNOWN
Conditions: Femoral Fractures
Interventions: DRUG: Dexmedetomidine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of MEM 3454 as Adjunctive Treatment in Combination With a Preexisting Antipsychotic in Patients With Cognitive Impairment Associated With Schizophrenia
Status: UNKNOWN
Conditions: Cognitive Impairment Associated With Schizophrenia
Interventions: DRUG: MEM 3454|DRUG: MEM 3454|DRUG: MEM 3454|DRUG: Placebo for MEM 3454
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smart Phone App for COLOnoscopic PREParation
Status: COMPLETED
Conditions: Colorectal Cancer Screening|Colonoscopy|Mass Screening
Interventions: OTHER: Bowel Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Ocular Dipyridamole in the Treatment of Dry Eye Symptomology in Subjects With Pterygium
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Pterygium
Interventions: DRUG: Dipyridamole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT