pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Pilot Study of the Feasibility of Setting up a Logbook for Allogeneic Haematopoietic Stem Cell Patients at the University Hospital of Amiens
Status: WITHDRAWN
Conditions: Allogeneic Disease|Hematopoietic Stem Cell
Interventions: OTHER: Evaluation of the feasibility of the establishment of a logbook in patients hospitalized for allogeneic haematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Trypan Blue on Endothelium of Diabetic Retinopathy Patients
Status: COMPLETED
Conditions: Cataract Diabetic
Interventions: PROCEDURE: Phacoemulsification with and without Trypan Blue capsule staining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrocautery Versus Scalpel for Surgical Skin Incisions in Cesarean Section.
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DEVICE: Scalpel|DEVICE: Electrocautery|PROCEDURE: Skin incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Changes in Plasma Glucose and Cardiovascular Disease in Diabetes
Status: UNKNOWN
Conditions: Diabetes|Hypoglycemia|Hyperglycemia|Cardiovascular Diseases|Sudden Cardiac Death
Interventions: OTHER: Hyperglycemia with slow decline in plasma glucose in type 1 diabetes|OTHER: Hyperglycemia with rapid decline in plasma glucose in type 1 diabetes|OTHER: Rebound hyperglycemia in type 1 diabetes|OTHER: Rebound euglycemia in type 1 diabetes|OTHER: Hypoglycemia in type 1 diabetes|OTHER: Hypoglycemia in type 2 diabetes|OTHER: Hypoglycemia in healthy controls|OTHER: Hyperglycemia in type 2 diabetes|OTHER: Hyperglycemia in healthy controls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of a Chinese Herbal Medicine for Long COVID Associated Fatigue
Status: RECRUITING
Conditions: Long COVID
Interventions: DRUG: Shenlingcao Oral Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Site Study of Music Therapy Interventions on Vitals, Feeding and Sleep in Premature Infants
Status: COMPLETED
Conditions: Prematurity|Sepsis|SGA|RDS
Interventions: OTHER: Music Intervention|OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Bp-MRI and Mp-MRI for Prostate Cancer Screening Accuracy
Status: RECRUITING
Conditions: Randomized Controlled Trial|Prostate Cancer|Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: bp-MRI prostate|DIAGNOSTIC_TEST: mp-MRI prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CME With Different Fluidic Parameters
Status: COMPLETED
Conditions: Cystoid Macular Edema Following Cataract Surgery
Interventions: PROCEDURE: microcoaxial phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma|Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab-Rwlc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Cevimeline Versus Pilocarpine in the Secretion of Saliva
Status: COMPLETED
Conditions: Dry Mouth
Interventions: DRUG: Cevimeline|DRUG: Pilocarpine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Non-inferiority of Treatment of Vulvovaginal Dryness With WO2085 Moisturising Cream in Comparison to a Cream With 0.1% Estriol
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DEVICE: WO2085 Moisturising Cream|DRUG: Estriol Cream 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
Status: COMPLETED
Conditions: Blunt Trauma|Penetrating Wound|Hemorrhagic Shock
Interventions: DRUG: 0.9% Sodium Chloride 250 mL bolus|DRUG: 0.9% Sodium Chloride 2000 mL bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A PK Study to Assess the Drug-drug Interaction of a BCRP Inhibitor on Adagrasib
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Adagrasib|DRUG: Eltrombopag + adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rehabilitation With HHFNC in COPD in Nocturnal NIV
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Exercise training with Humified High Flow Nasal Cannula|OTHER: Exercise training - Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SAR440340|DRUG: Dupilumab|DRUG: Fluticasone or Fluticasone/salmeterol combination|DRUG: Placebo for SAR440340|DRUG: Placebo for dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iggy and the Inhalers: A Study to Assess the Impact of an Asthma Education Program in School Age Children
Status: WITHDRAWN
Conditions: Asthma
Interventions: BEHAVIORAL: Iggy and the Inhalers Asthma Education for Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Watermelon/UBIQuinone Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplantation
Interventions: DIETARY_SUPPLEMENT: coenzyme Q10|OTHER: Watermelon diet|OTHER: Usual Diet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PersAFOne III: Feasibility Study of the FARAPULSE Pulsed Field Ablation System Plus - PersAF in the Treatment of Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: FARAPULSE™ Pulsed Field Ablation System Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dasatinib With Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Group 1: Radiation, Paclitaxel,Carbo, Dasatinib days 1-47|DRUG: Group 2: Radiation, Paclitaxel, Carbo, Dasatinib days 1-38
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
Status: COMPLETED
Conditions: Primary Myelofibrosis|Thrombocytosis|Essential Thrombocythemia|Polycythemia Vera|Myeloproliferative Disorders|Bone Marrow Diseases|Hematologic Diseases|Blood Coagulation Disorders|Blood Platelet Disorders|Hemorrhagic Disorders
Interventions: DRUG: LDE225|DRUG: INC424
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Erectile Function and Quality of Life After Prostate Cancer Treatment
Status: TERMINATED
Conditions: Prostate Cancer|Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction Following Simple Prostatectomy|Erectile Dysfunction
Interventions: BEHAVIORAL: Cognitive-behavioral Meetings|DRUG: sildenafil citrate|DEVICE: Vacuum Constriction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Effects of Food or Proton Pump Inhibitor on the Pharmacokinetics of Itraconazole in Healthy Volunteers
Status: COMPLETED
Conditions: Achlorhydria
Interventions: DRUG: Itraconazole 200 mg|DRUG: Esomeprazole 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Readability of Consent Forms on the Understanding of the Information Received by Volunteers
Status: COMPLETED
Conditions: Outcome Assessments (Health Care)|Comprehension|Language
Interventions: OTHER: Questionnaire of understanding
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intravitreal Ranibizumab and TA Combination Therapy vs. Ranibizumab Monotherapy in Polypoidal Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Wet Macular Degeneration
Interventions: DRUG: Triamcinolone Acetonide|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to Moderate Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Telotristat Etiprate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Comparison of Fixed- and Mobile-Bearing Total Knee Arthroplasties (TKAs) in Patients With OA ≤50 Years Old
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: anatomic modular fixed-bearing|DEVICE: low contact stress rotating platform mobile-bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tirzepatide|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vertical Bone Gain After Ridge Augmentation With APRF & Xenograft Vs Collagen Membrane & Xenograft. RCT
Status: UNKNOWN
Conditions: Bone Loss, Alveolar
Interventions: PROCEDURE: Xenograft and Collagen membrane|PROCEDURE: Xenograft and APRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depressed Mothers in Rural Areas: Web-Facilitated Cognitive Behavioral Treatment
Status: COMPLETED
Conditions: Maternal Care Patterns
Interventions: BEHAVIORAL: Mom-Net|BEHAVIORAL: Coach-facilitated Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of VA (Venetoclax, Azacitidine), VACl (VA, Cladribine), VACh (VA, Chidamide), and Alternating VACl/VACh in Newly Diagnosed Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, Adult|Newly Diagnosed
Interventions: DRUG: VACl|DRUG: VACh|DRUG: VACl Alternating With VACh|DRUG: VA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Consolidative Involved-site Radiotherapy for Patients With Limited-stage Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: RADIATION: Consolidation involved-site radiotherapy (ISRT)|RADIATION: Consolidation involved-field radiotherapy (IFRT)|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: vincristine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Adverse Reactions Occuring in Children Treated by Biotherapy for Chronic Inflammatory Disease
Status: COMPLETED
Conditions: Biotherapy|Chronic Inflammatory Disease|Allergic Skin Reaction|Pediatric Disorder|Dermatologic Complication|Gastrointestinal Disease|Ophthalmology|Rheumatology
Interventions: OTHER: dermatological consultation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase III rhu_GM-CSF + 3 Induction Regimens in Adults With Acute Non-Lymphocytic Leukemia
Status: COMPLETED
Conditions: Adult Patients (Over 55) With Acute Non-Lymphocytic Leukemia
Interventions: DRUG: GM-CSF priming|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shenfu Injection for Postoperative Delirium (SFI for POD)
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: DRUG: Shen-Fu injection|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis:
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: DIETARY_SUPPLEMENT: Vitamin K|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Perioperative Dexamethasone on Postoperative Outcome in IBD
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Dexamethasone|Postoperative Ileus|Postoperative Complications
Interventions: DRUG: Dexamethasone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Tolerability of Tobramycin Podhaler in Bronchiectasis Patients With Chronic Pseudomonas Aeruginosa Infection
Status: UNKNOWN
Conditions: Bronchiectasis With Chronic Infection With Pseudomonas Aeruginosa
Interventions: DRUG: Tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Stroke, Ischemic|Intracranial Atherosclerosis|Posterior Circulation Brain Infarction
Interventions: OTHER: we are aiming to develop a Scoring system based on certain variables derived from both groups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of E5555 and Its Effects on Markers of Intravascular Inflammation in Subjects With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: E5555|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postmarket Study to Evaluate Biovance® in Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: OTHER: Biovance®|OTHER: Standard of Care, Diabetic Foot Ulcers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Exercises for Patients With Stroke
Status: COMPLETED
Conditions: Cerebrovascular Disorders|Brain Infarction|Brain Ischemia|Stroke
Interventions: BEHAVIORAL: home-based group (HBG)|BEHAVIORAL: supervised exercise group (SEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: ER-Positive HER2-Negative Breast Cancer
Interventions: DRUG: AZD9833|DRUG: Anastrozole|DRUG: Anastrozole placebo|DRUG: AZD9833 placebo|DRUG: Palbociclib|DRUG: Luteinizing hormone-releasing hormone (LHRH) agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide J|DRUG: Semaglutide B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis
Status: WITHDRAWN
Conditions: Inflammation|Cough|Rhinitis
Interventions: DRUG: diphenhydramine + dropropizine + pseudoephedrine|DRUG: Dropropizine and fixed dose combination of pseudoephedrine hydrochloride + brompheniramine maleate (Dimetapp® elixir).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients
Status: COMPLETED
Conditions: Infection Viral|Uveitis, Posterior
Interventions: DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Protein Quality and Time-factor by Consumption of a Pre-meal on Postprandial Lipemia in Subjects With the Metabolic Syndrome.
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Whey protein|OTHER: Casein|OTHER: Gluten protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Implementation of Out-of-HOspital Administration of the Long-Acting Cabotegravir+Rilpivirine
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1 Infection
Interventions: DRUG: Hospital long-acting Vocabria (cabotegravir) 600 mg and long-acting Rekambys (rilpivirine) 900 mg administration|DRUG: Out of Hospital long-acting Vocabria (cabotegravir) 600 mg and long-acting Rekambys (rilpivirine) 900 mg administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Clinical Trial of tDCS to Evaluate Cognitive Ability in Depression Patients
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: Transcranial direct current stimulation_High real|DEVICE: Transcranial direct current stimulation_Low real|DEVICE: Transcranial direct current stimulation_Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Radiofrequency, Vein Stripping and CHIVA for Venous Insufficency
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: Radiofrequency|PROCEDURE: Saphenous vein stripping|PROCEDURE: CHIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19
Status: COMPLETED
Conditions: Microbiome
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG|DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-level Laser Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics
Status: COMPLETED
Conditions: Chronic Periodontitis|Diabetes Mellitus
Interventions: PROCEDURE: Periodontal ultrasonic debridement|DEVICE: Debridement plus low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Five Day Clinical Study to Examine the Effects of a Benzoyl Peroxide Treatment on Facial Acne Lesions
Status: COMPLETED
Conditions: Skin Diseases
Interventions: DRUG: 3% Benzoyl Peroxide|DRUG: 3% Benzoyl Peroxide Placebo|DRUG: Neutrogena Rapid Clear®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pramipexole ER vs. Placebo in Fibromyalgia
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: pramipexole ER|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Different Protocols of Negative Pressure Therapy for Healing of Chronic Ulcers
Status: UNKNOWN
Conditions: Chronic Ulcers|Negative Pressure Therapy
Interventions: DEVICE: Negative pressure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CyberKnife Stereotactic Radiosurgery for Low and Intermediate Risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: CyberKnife Stereotactic Ablative Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomised Control Trial to Study the Effectiveness of a Health Service Innovation Using a Modified Virtual Ward Model to Prevent Unscheduled Readmission of High Risk Patients
Status: COMPLETED
Conditions: Chronic Diseases
Interventions: OTHER: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Virtual Ileostomy Versus Conventional Loop Ileostomy
Status: NOT_YET_RECRUITING
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Virtual ileostomy|PROCEDURE: Diverting ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma
Status: RECRUITING
Conditions: Diffuse Glioma|Radionecrosis of Brain|High Grade Glioma|Glioblastoma Multiforme
Interventions: DRUG: Chlorophyllin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Depression Treatment for Low Income Substance Users
Status: COMPLETED
Conditions: Substance Use Disorder
Interventions: BEHAVIORAL: LETS ACT Behavioral Activation Treatment|BEHAVIORAL: Nondirective Therapy (NDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Induction Therapy With VELCADE and Vorinostat in Patients With Surgically Resectable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Velcade and Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression
Status: COMPLETED
Conditions: Major Depressive Disorder|Depressive Symptoms
Interventions: BEHAVIORAL: Memory Specificity Training|BEHAVIORAL: Education and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Experimental Protocol for the Study of Brain Functional Magnetic Resonance Imaging in Female With Urgent Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: bio-feedback treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Assessment of the Ability of Fentanyl Citrate Nasal Spray to Manage Breakthrough Pain in Cancer Patients.
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Fentanyl Citrate Nasal Spray (FCNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Topical OPA-15406 Ointment to Treat Participants With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: OPA-15406|DRUG: Vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of AMP Application After Non-surgical Periodontal Therapy on Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Oral biological antimicrobial gel|DRUG: minocycline hydrochloride ointment|OTHER: SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Nimotuzumab in Solid Tumours
Status: COMPLETED
Conditions: Advanced and/or Metastatic Solid Tumours
Interventions: DRUG: Nimotuzumab (TheraCIM h-R3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Falls in General Practitioner for Community-dwelling Older Adults [PreFalls]
Status: COMPLETED
Conditions: Accidental Falls/Prevention & Control|Risk Assessment|General Practitioner Education|Humans|Multicenter Study|Randomized Controlled Trial
Interventions: OTHER: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndromes|Coronary Artery Disease
Interventions: BEHAVIORAL: Educational intervention programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AK106-001616|DRUG: AK106-001616|DRUG: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modifying Physical Activity and Sedentary Time in Filipino Faith Leaders
Status: COMPLETED
Conditions: Physical Activity and Sedentary Behavior|Healthy Aging
Interventions: BEHAVIORAL: Light-to-Moderate Physical Activity / Sedentary Time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations
Status: RECRUITING
Conditions: Adrenal Incidentaloma|Hypercortisolism|Adrenal Tumor
Interventions: PROCEDURE: Adrenalectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation and Comparison of the Appendicitis Inflammatory Response Score and Adult Appendicitis Score
Status: COMPLETED
Conditions: Acute Appendicitis|Acute Appendicitis With Rupture
Interventions: DIAGNOSTIC_TEST: Appendicitis Inflammatory Response|DIAGNOSTIC_TEST: Adult Appendicitis Score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing TR Band to Statseal in Conjunction With TR Band II
Status: COMPLETED
Conditions: Arterial Occlusion|Cardiovascular Diseases|Atherosclerosis|Hematoma|Anticoagulant-induced Bleeding|Coronary Artery Disease
Interventions: DEVICE: Statseal with TR Band|DEVICE: TR band only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: METIMMOX-2: Metastatic pMMR/MSS Colorectal Cancer - Shaping Anti-Tumor Immunity by Oxaliplatin
Status: RECRUITING
Conditions: Colorectal Adenocarcinoma|Mucinous Adenocarcinoma|Signet Ring Cell Adenocarcinoma
Interventions: DRUG: Nivolumab|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESET-psychotherapy: the Effectiveness of Trauma-focused Therapy in Patients With Depression and Childhood Trauma
Status: UNKNOWN
Conditions: Major Depressive Disorder|Childhood Trauma
Interventions: BEHAVIORAL: Treatment as usual (TAU) for depression|BEHAVIORAL: Trauma-focused therapy (TFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder
Status: TERMINATED
Conditions: Pediatric Bipolar Disorder|Pediatric OCD
Interventions: DRUG: fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Selective Laser Photocoagulation in Twin-Twin Transfusion Syndrome
Status: UNKNOWN
Conditions: Twin to Twin Transfusion Syndrome
Interventions: PROCEDURE: Fetoscopic Selective Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for Smoking Cessation
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation|Smoking, Tobacco|Smoking Reduction
Interventions: BEHAVIORAL: Contingency Management - Increasing|BEHAVIORAL: Fixed payments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Chemotherapy Response Monitoring With 18F-choline PET/CT in Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer
Interventions: DRUG: IV fluorine-18 labeled methylcholine before PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treating Sleep Apnea in Women Veterans
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: BEHAVIORAL: Acceptance and the Behavioral Changes to Treat Sleep Apnea (ACB-SA)|BEHAVIORAL: Non-directive sleep apnea education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fasting and Shifted Timing (FAST) of Eating Study
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Online handouts describing how to follow each diet for 1 week each
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of VR101 as a Personal Lubricant
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological
Interventions: DEVICE: VR101 Lubricating Intravaginal Ring|DEVICE: Sham Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin
Status: COMPLETED
Conditions: Herpes Simplex Infections|Human Papillomavirus|Epstein-Barr Virus Infections|Varicella-zoster Virus Infection|Cytomegalovirus Infections
Interventions: DIETARY_SUPPLEMENT: Gene-Eden-VIR/Novirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-label Study to Assess Increasing Levels of NAD+(Nicotinamide Adenine Dinucleotide)
Status: COMPLETED
Conditions: Increase in Blood Levels of Nicotinamide Adenine Dinucleotide (NAD+)
Interventions: DIETARY_SUPPLEMENT: Oral supplement A|DIETARY_SUPPLEMENT: Oral supplement B|DIETARY_SUPPLEMENT: Oral supplement C|DIETARY_SUPPLEMENT: Oral supplement D|DIETARY_SUPPLEMENT: Oral Supplement D in combination with oral supplement C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: BrainHQ Cognitive Training Modules|BEHAVIORAL: BrainHQ People Skills Modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Higher Than Maximum 450IU Gonadotropin Dose in an In-vitro Fertilization Cycle
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: menotropins for injection|DRUG: urofollitropin for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Esophageal Stent Migration in Esophageal Strictures
Status: WITHDRAWN
Conditions: Stent Migration
Interventions: DEVICE: OTSC Stentfix|PROCEDURE: Stent Suturing / Endoscopic Clips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inmediate Effect of the Visualization of Action
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain|Musculoskeletal Pain
Interventions: OTHER: observed action and motor imaginery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Temporary Placement of a Transvenous Phrenic Nerve Stimulator for Diaphragm Pacing Using Jugular Access
Status: COMPLETED
Conditions: Ventilator-Induced Lung Injury
Interventions: DEVICE: LIVE Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Neck-Trunk Stabilization Exercises and Bobath Therapy Spastic Diplegic Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy Spastic Diplegia
Interventions: OTHER: Neck-Trunk Stabilization Exercises and conventional physical therapy|OTHER: Bobath Therapy and conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 5-azacytidine Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: azacitidine|DRUG: standard chemotherapy (7+3 scheme): Daunorubicin, Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patients
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Metastatic Colon Cancer|Metastatic Prostate Cancer
Interventions: DRUG: Foxy-5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Bioavailability Between Two Products Containing Paliperidone 100 mg in the Form of a Prolonged Release Suspension for Injection in Patients With Schizophrenia Who Are Already Stabilized in This Treatment
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone|DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bevacizumab, Metronomic Chemotherapy (CM), Diet and Exercise After Preoperative Chemotherapy for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Cyclophosphamide|DRUG: Methotrexate|BEHAVIORAL: Lifestyle: Diet|BEHAVIORAL: Lifestyle: Diet+Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Voxilaprevir in Adults With Normal Renal Function and Severe Renal Impairment
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: Voxilaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone and Ketamine for Neuropathic Pain Treatment
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Methadone|DRUG: Ketamine|DRUG: Methadone plus Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Fascia Iliaca Compartment Block in Geriatric Patients With Hip Fracture
Status: COMPLETED
Conditions: Hip Fractures
Interventions: PROCEDURE: Fascia iliaca compartment block|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases
Status: UNKNOWN
Conditions: Breast Cancer|Brain Metastases
Interventions: DRUG: BEEP regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of New Formulation of Glatiramer Acetate
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate|DRUG: Experimental Glatiramer Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Plus Chemotherapy vs. Chemoradiotherapy for Thoracic Squamous Esophageal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy|Radiation Therapy
Interventions: DRUG: Camrelizumab|DRUG: Paclitaxel|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Vinca Alkaloids on c-Jun N-terminal Kinase (JNK) Phosphorylation in Patients With Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reducing Depressive Symptoms in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Mind-Body Skills Training (MBST)|BEHAVIORAL: Supportive Counseling (SC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Tipifarnib, Docetaxel, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIA or Stage IIIB Breast Cancer
Status: COMPLETED
Conditions: Adult Solid Neoplasm|Inflammatory Breast Carcinoma|Male Breast Carcinoma|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Peripheral Magnetic Stimulation to Reduce Pain in Knee Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: Repetitive Peripheral Magnetic Stimulation|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naproxen Codeine in Arthroscopic Surgery
Status: COMPLETED
Conditions: Arthroscopic Meniscus Surgery
Interventions: DRUG: Group N:Naproxen sodium|DRUG: Group NC :naproxen sodium codeine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Stimulation in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Vibrotactile stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Accuracy, Impact, and Operational Challenges of GeneXpert Use for TB Case Finding Among HIV-infected Persons
Status: COMPLETED
Conditions: Tuberculosis|Human Immunodeficiency Virus
Interventions: DEVICE: Xpert device|OTHER: Intensified TB Case Finding (ICF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Furosemide-induced Diuresis With Matched Dehydration Compared to Standard Diuretic Therapy in Patients With Acute Heart Failure and Overt Fluid Overload
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DEVICE: RenalGuard device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Egg-Based High Protein Meal on Hypertensive Response to Exercise
Status: COMPLETED
Conditions: Blood Pressure|Cardiovascular Risk Factor
Interventions: OTHER: Normal Protein|OTHER: HIgh Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Retrospective Study on the Evolution of CIN 1 to 3 in Per and Postpartum in Nancy From 2014 to 2022
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: cervical biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension
Status: COMPLETED
Conditions: Pain, Postoperative|Bunion
Interventions: DRUG: COV795|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Control Training for Remitted Depressed Patients
Status: COMPLETED
Conditions: Major Depression in Remission
Interventions: BEHAVIORAL: Cognitive Control Training|BEHAVIORAL: Low Cognitive Load Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A First Time in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Single and Repeat Doses of GSK2485852 in Chronically Infected Hepatitis C Subjects
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: GSK2485852 70 mg|DRUG: GSK2485852 420 mg|DRUG: placebo|DRUG: placebo|DRUG: GSK2485852 420 mg|DRUG: GSK2485852 420 mg|DRUG: GSK2485852 630 mg|DRUG: GSK2485852 70 mg + Ritonavir 100mg|DRUG: GSK2485852 210 mg + Ritonavir 100mg|DRUG: GSK2485852 210 mg +Ritonavir 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Newly Diagnosed Immune Thrombocytopenia Testing the Standard Steroid Treatment Against Combined Steroid & Mycophenolate
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Evaluating Different Methods of Measuring Depression Treatment Response
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: PROCEDURE: electronic diary|DRUG: Sertraline|DRUG: Placebo|PROCEDURE: voice acoustics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating GDC-0980 Administered Once Daily in Patients With Refractory Solid Tumors or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma, Solid Cancers
Interventions: DRUG: GDC-0980
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT