pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
Status: COMPLETED
Conditions: Insomnia|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: eszopiclone|DRUG: eszopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Cognitive Disorders
Interventions: BEHAVIORAL: 5-month aerobic exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Food Effect and Mass Balance Study of XZP-3621 Tablets
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: XZP-3621|DRUG: XZP-3621|DRUG: XZP-3621|DRUG: XZP-3621|DRUG: XZP-3621|DRUG: XZP-3621|DRUG: XZP-3621
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Step Count Using Pedometer for Sarcopenic Management in Patient With Cirrhosis: Randomized Controlled Trial
Status: ENROLLING_BY_INVITATION
Conditions: Sarcopenia|Cirrhosis, Liver|Daily Step Count
Interventions: OTHER: Encourage using pedometer|DEVICE: pedometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics on Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: Probiotic capsules containing Lactobacillus rhamnosus GR-1 and L. reuteri RC-14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety of Combination Montelukast/Loratadine in Mexican Participants With Allergic Rhinitis (MK-0476A-484)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Montelukast 10 mg/loratadine 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acid Suppression Medication on Pediatric Microbiome
Status: TERMINATED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Omeprazole (suspension)|OTHER: Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Topical Tetracycline and Dexamethasone on Periodontal and Pulpal Regeneration of Replanted Avulsed Teeth
Status: COMPLETED
Conditions: Dental Trauma|Avulsion|Periodontal Regeneration|Pulpal Regeneration|Topical Dexamethasone|Topical Tetracycline
Interventions: PROCEDURE: Tetracycline|PROCEDURE: Dexamethasone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome
Status: RECRUITING
Conditions: Wallenberg Syndrome
Interventions: DEVICE: Virtual Reality Therapy|BEHAVIORAL: Conventional dysphagia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Sutures in Hand Surgery
Status: UNKNOWN
Conditions: All Minor Hand Surgery Including|Carpal Tunnel Syndrome|Trigger Finger|Ganglion Cysts|De Quervain Syndrome|Dupuytren Contracture
Interventions: PROCEDURE: Absorbable Chromic gut sutures|PROCEDURE: Non-absorbable Nylon sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Severity of Hepatic Fibrosis by Magnetic Resonance Elastography in the Diagnosis of Endogenous Hypercorticism
Status: RECRUITING
Conditions: Cushing Syndrome|Metabolic Syndrome
Interventions: DEVICE: Magnetic resonance elastography (MRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Mydriatic Eye Drops on Cerebral and Mesenteric Oxygenation in Preterm Infants
Status: UNKNOWN
Conditions: Prematurity of Fetus
Interventions: DEVICE: near infrared spectroscopy: invos 5100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Effectiveness and Safety of Deucravacitinib in Participants With Non-Pustular Palmoplantar and Genital Psoriasis
Status: RECRUITING
Conditions: Palmoplantar Psoriasis|Genital Psoriasis
Interventions: DRUG: Deucravacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone?
Status: NOT_YET_RECRUITING
Conditions: Healthy Aging|Age-Related Sarcopenia|Testosterone Deficiency
Interventions: DRUG: Saline|DRUG: Testosterone Undecanoate|DRUG: Saline + Resistance exercise training|DRUG: Testosterone Undecanoate + Resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
Status: COMPLETED
Conditions: Carotid Atherosclerosis|Carotid Stenosis|Ischemic Attack|Stroke|Bleeding
Interventions: PROCEDURE: Transradial carotid artery stenting|PROCEDURE: Transfemoral carotid artery stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Perioperative Hypothermia in Transurethral Resection Under Spinal Anaesthesia
Status: COMPLETED
Conditions: Hypothermia; Anesthesia|Perioperative Complication|Regional Anesthesia Morbidity|Temperature Change, Body|Transurethral Resection Syndrome
Interventions: DEVICE: WarmTouch total body blanket, Covidien Ltd, Mansfield, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicentre Clinical Investigation to Assess Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Chondroitin Sulfate in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Hyaluronic Acid Combined With Chondroitin Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9701 Paclitaxel in Treating Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: MEDI4736|BIOLOGICAL: tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA-Guided Second Line Adjuvant Therapy For High Residual Risk, Stage II-III, Hormone Receptor Positive, HER2 Negative Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Fulvestrant|DRUG: Adjuvant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
Status: RECRUITING
Conditions: Metastatic Solid Cancers|Colorectal Cancer|Breast Cancer|Non-Small Cell Lung Cancer|Gastrointestinal Cancer|Ovarian Cancer|Genitourinary Cancer
Interventions: DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: KRAS TCR-Transduced PBL|BIOLOGICAL: GRT-C903/GRT-R904
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Type of Anesthesia Influence Inflammation Change After Breast Surgery?
Status: COMPLETED
Conditions: Breast Cancer Female
Interventions: DRUG: Midazolam|PROCEDURE: PECS|PROCEDURE: Opioid-free general anesthesia|PROCEDURE: General anesthesia|PROCEDURE: Postoperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Examining the Effect of Metaverse-Based Epilepsy Education
Status: NOT_YET_RECRUITING
Conditions: Examining the Effect of Metaverse-based Epilepsy Education on Parents' Knowledge Level
Interventions: OTHER: Metaverse|OTHER: Polyclinic information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness and Safety of Keeogo™ Dermoskeleton in Subjects With Mobility Impairments Due to Stroke
Status: UNKNOWN
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Stroke|Hemiparesis|Cerebral Vascular Accident
Interventions: DEVICE: Keeogo™ Dermoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin Resistance
Status: COMPLETED
Conditions: Metabolic Syndrome|Bipolar Depression|Insulin Resistance
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "ORBIT" Versus "HAS-BLED" Scores in Predicting Major Bleeding in Patients With Atrial Fibrillation Receiving Oral Anticoagulants.
Status: NOT_YET_RECRUITING
Conditions: Patients With Atrial Fibrillation Receiving Oral Anticoagulants
Interventions: DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Project Healthy Eating in Adults. A Study on the Health Effects of Fish Intake in Overweight Adults (FINS)
Status: COMPLETED
Conditions: Overweight or Obese Adults|Healthy
Interventions: OTHER: Salmon Group|OTHER: Cod Group|OTHER: Meat Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Renal Protective Effects of Restricted Protein Dietary With α-keto Acid in CAPD Patients
Status: COMPLETED
Conditions: Renal Function Disorder
Interventions: DRUG: α-Keto Acid with restricted protein diet|DRUG: Placebo plus restricted protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells
Status: RECRUITING
Conditions: Thalassemia, Beta|Thalassemia Major
Interventions: BIOLOGICAL: VGB-Ex01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methods of Chlorhexidine Cleansing to Prevent Ventilator-Associated Pneumonia (VAP)
Status: COMPLETED
Conditions: Ventilator-associated Pneumonia
Interventions: DRUG: Chlorhexidine|DRUG: 0.9% sodium chloride injection|DEVICE: Endotracheal tube|DEVICE: Fiber bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Duration of Metabolic Effect of a Single Bolus of sc Injected Lantus Compared to NPH Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HDAC Inhibitor AR-42 and Pomalidomide in Treating Patients With Relapsed Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: HDAC Inhibitor AR-42|OTHER: Laboratory Biomarker Analysis|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE
Status: COMPLETED
Conditions: Massive Pulmonary Embolism
Interventions: DRUG: Recombinant nonimmunogenic staphylokinase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Randomized Controlled Trial of Health Impact of Pistachios on Women With Gestational Diabetes Mellitus
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: OTHER: pistachios consumption of 1.5 oz thrice per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Optimise Levels of Vitamin D for Rhinovirus Protection
Status: WITHDRAWN
Conditions: Common Cold
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Lidocaine-Prilocaine Combination and Vapocoolant for IV Cannulation Pain in the ED
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Vapocoolant spray|DRUG: Lidocaine-Prilocaine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Versus Land-mark Method for Spinal Anesthesia in Super Obesity Parturients
Status: RECRUITING
Conditions: Obesity, Morbid
Interventions: DEVICE: Procedure/Surgery: Ultrasound method group|DEVICE: Landmark method group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serosurveillance Study of Maternally Derived Anti-GBS Antibody
Status: ACTIVE_NOT_RECRUITING
Conditions: Group B Streptococcus Carrier in Childbirth|Group B Streptococcal Infection, Late-Onset|Group B Streptococcal Infection, Early-Onset|Group B Streptococcus Neonatal Sepsis|Group B Strep Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AB-16B5 Combined With Docetaxel in Subjects With Metastatic Non-Small Cell Lung Cancer (EGIA-002)
Status: COMPLETED
Conditions: NSCLC Stage IV
Interventions: DRUG: AB-16B5|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Anterior Cruciate Ligament Repair Versus Reconstruction for Acute Anterior Cruciate Ligament Injury
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: ACL Repair|PROCEDURE: ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Incidence of Perioperative Hypothermia at the Surgical Area of Parc Tauli Hospital Universitari, Sabadell
Status: COMPLETED
Conditions: Hypothermia
Interventions: DEVICE: The SpotOn system that encompasses the registration unit (3M SpotOn Control Unit), disposable sensor (3M SpotOn Control Sensor) along with the cords and electric power unit.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Yathu Yathu: An Impact Evaluation of Community-based Peer-led Sexual and Reproductive Health Services
Status: UNKNOWN
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: OTHER: Comprehensive sexual and reproductive health services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Solid Tumors, Adult|PIK3CA Mutation-Related Tumors|PIK3CA Mutation|Human Papillomavirus-Related Carcinoma|HPV-Related Squamous Cell Carcinoma|Human Papillomavirus-Related Squamous Cell Carcinoma|Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: DRUG: Alpelisib|DRUG: Carboplatin|DRUG: Hyperpolarized Carbon-13 (13C) Pyruvate|DEVICE: Continuous Glucose Monitor (CGM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Ai-based Endoscopic Ultrasound Navigation System in the Training of Endoscopic Ultrasonics
Status: NOT_YET_RECRUITING
Conditions: Endoscopic Ultrasound
Interventions: DEVICE: Artificial intelligence assisted system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study
Status: RECRUITING
Conditions: Mitral Regurgitation|Tricuspid Regurgitation|Valvular Heart Disease
Interventions: DEVICE: Abbott SJM Rigid Saddle Ring|DEVICE: Abbott SJM Séguin Ring|DEVICE: Abbott SJM Tailor Ring|DEVICE: Abbott SJM Tailor Band
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma
Status: COMPLETED
Conditions: Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma|Stage III Childhood Hodgkin Lymphoma|Stage IV Childhood Hodgkin Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: doxorubicin hydrochloride|DRUG: liposomal vincristine sulfate|DRUG: vinorelbine tartrate|DRUG: cyclophosphamide|DRUG: etoposide phosphate|DRUG: prednisone|BIOLOGICAL: filgrastim|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Glaucoma Drops on of the Duration of a Pure Intraocular Gas Bubble
Status: COMPLETED
Conditions: Scleral Buckling
Interventions: DRUG: Timolol-dorzolamide (Glaucoma drops)|DRUG: standard post-operative topical drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Cognition and Interaction Training for Adults With Psychotic Disorders: An Open Pilot Study in Finland
Status: COMPLETED
Conditions: Psychotic Disorder|Cognitive Function 1, Social
Interventions: BEHAVIORAL: Social Cognition and Interaction Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy|Spinal Muscular Atrophy Type 3|Spinal Muscular Atrophy Type 2|SMA|Neuromuscular Diseases|Muscular Atrophy|Atrophy|Muscular Atrophy, Spinal|Neuromuscular Manifestations|Anti-myostatin
Interventions: DRUG: Apitegromab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacology Study of Aerosolized Liposomal
Status: WITHDRAWN
Conditions: Lung Diseases|Cancer
Interventions: DRUG: L9NC: Liposomal 9-Nitro-20 (S)-Camptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent
Status: WITHDRAWN
Conditions: Acute Kidney Injury
Interventions: DRUG: deferiprone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: [11C]-Pittsburgh Compound B ([11C]PiB)|DRUG: F 18 AV-1451 (Flortaucipir)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Daily Versus Twice Per Day Tamsulosin for Ureteral Stent Symptoms
Status: UNKNOWN
Conditions: Ureteral Diseases
Interventions: DRUG: Tamsulosin BID|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Extension to Protocol 09-1, Efficacy and Safety Study of the EndoBarrier® Gastrointestinal Liner System
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DEVICE: EndoBarrier
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: TLL018 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allopurinol in Acute Coronary Syndrome
Status: TERMINATED
Conditions: Chronic Stable Angina
Interventions: DRUG: Allopurinol|DRUG: Allopurinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Diabetic Neuropathy|Low Back Pain
Interventions: DRUG: Lidoderm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neural Mobilization in Bells Palsy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Bell Palsy
Interventions: OTHER: Neural Mobilisation|OTHER: Massage therapy|DIAGNOSTIC_TEST: Faradic electrical stimulation|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Reducing Tendon Compression in the Treatment of Insertional Achilles Tendinopathy
Status: COMPLETED
Conditions: Insertional Achilles Tendinopathy
Interventions: OTHER: Exercise therapy|OTHER: Exercise therapy (usual care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of GTx-758 on Serum PSA and Testosterone in Men With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: GTx-758 125 mg|DRUG: GTx-758 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Primary Tumor Radiotherapy for Patients With Stage Ⅳ NSCLC
Status: UNKNOWN
Conditions: Radiotherapy|Nonsmall Cell Lung Cancer, Stage IV
Interventions: OTHER: Drug therapy concurrent radiotherapy for primary tumor omitted CTV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Home Based Pulmonary Rehabilitation on Exacerbation and Hospital Admission in Severe COPD
Status: RECRUITING
Conditions: COPD Exacerbation
Interventions: DEVICE: Teknikel Spirobank Home Type Respiratory Function Tester (Homespirometer)|OTHER: Exercise Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agonist Versus Classical HCG Trigger (Poor Responders, Normoresponders and High Responders)
Status: UNKNOWN
Conditions: Ovulation Induction|In Vitro Fertilization (IVF)|Infertility, Female|Oocytes
Interventions: DRUG: Gonadotropin Releasing Hormone Agonists (GNRH-A)|DRUG: Human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Outcome of Partial and Full Pulpotomy in Irreversible Pulpits
Status: UNKNOWN
Conditions: Carious Exposure of Pulp|Irreversible Pulpitis|Pulpotomy
Interventions: PROCEDURE: Partial pulpotomy|PROCEDURE: Full Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community Dissemination of an Evidence-based Colorectal Cancer (CRC) Screening Intervention
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer
Interventions: BEHAVIORAL: Educational program and FOBT kits|BEHAVIORAL: Educational program and FOBT kits, and technical assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Dual Diagnosis Inpatients: Telephone Monitoring RCT to Improve Outcomes
Status: COMPLETED
Conditions: Diagnosis, Dual (Psychiatry)
Interventions: BEHAVIORAL: Telephone Monitoring (TM) with Motivational Interviewing|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Natalizumab (Tysabri) on Sexual Dysfunction in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Tysabri ® (Natalizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Natural Cycle vs. Modified Natural Cycle vs. Artificial Cycle Protocol for Endometrial Preparation.
Status: COMPLETED
Conditions: IVF|Frozen Embryo Transfer
Interventions: PROCEDURE: NC|PROCEDURE: mNC|PROCEDURE: AC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injection: A Innovational Approach for Joint Disorder
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Dysfunction
Interventions: BEHAVIORAL: Routine rehabilitation treatment|BEHAVIORAL: Intra-articular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers
Status: COMPLETED
Conditions: Smoking|Tobacco Use|Tobacco Smoking
Interventions: OTHER: P1012919 nicotine pouch|OTHER: P1012915 nicotine pouch|OTHER: P1012914 nicotine pouch|OTHER: P1013315 nicotine pouch|OTHER: P1013119 nicotine pouch|OTHER: P1013218 nicotine pouch|OTHER: P1012818 nicotine pouch|OTHER: P1312915 nicotine pouch|OTHER: P1312914 nicotine pouch|OTHER: P1313015 nicotine pouch|OTHER: P1313314 nicotine pouch|OTHER: P1312815 nicotine pouch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TMS-evoked Potentials During Repetitive Transcranial Magnetic Stimulation on the Primary Motor Cortex
Status: RECRUITING
Conditions: Repetitive Transcranial Magnetic Stimulation|Motor Cortex|Transcranial Magnetic Stimulation|Pain Thresholds|Electroencephalography
Interventions: OTHER: Real rTMS|OTHER: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Moxifloxacin in Adjuvant Treatment of Patients With Operable Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: standard adjuvant chemotherapy plus moxifloxacin|DRUG: standard adjuvant chemotherapy plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
Status: UNKNOWN
Conditions: Herniated Disc|Intervertebral Disc Displacement
Interventions: DRUG: Gabapentin , Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Imaging of Melanoma for Alpha-Particle Radiotherapy
Status: COMPLETED
Conditions: Melanoma (Skin)|Melanoma Stage IV|Melanoma, Uveal|Melanoma, Mucosal
Interventions: DRUG: [203Pb]VMT01|DRUG: [68Ga]VMT02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Postprandial Glycemic Response to Polyphenol-fortified Snack Bars
Status: COMPLETED
Conditions: Blood Sugar Response
Interventions: OTHER: Fruit extracts high in polyphenols|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Polatuzumab vedotin (PV)|DRUG: Rituximab|DRUG: Hyaluronidase|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Dexamethasone|DRUG: GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Anetumab ravtansine (BAY94-9343)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension|DRUG: Brinzolamide ophthalmic suspension, 1%|DRUG: Brimonidine tartrate ophthalmic solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Food on the Pharmacokinetics of ER OROS Paliperidone in Healthy Japanese Volunteers
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ER OROS paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Orally Administered Engineered Probiotics (CBT102-A) for the Treatment of Children With Phenylketonuria
Status: RECRUITING
Conditions: Phenylketonuria
Interventions: BIOLOGICAL: CBT102-A capsule|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: darbepoetin alfa|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MT-3995 in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: MT-3995 Low|DRUG: MT-3995 Middle|DRUG: MT-3995 High|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRSA Decolonization in Complicated Carriage
Status: RECRUITING
Conditions: MRSA
Interventions: DRUG: doxycycline 200 mg q.d. - rifampicin 600mg b.i.d.|DRUG: trimethoprim 200mg b.i.d. - rifampicin 600mg b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Intervention to Improve Depressive Symptoms Among Older Adults (VIDACTIVA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: VIDACTIVA sessions|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Health enSuite Caregivers: an App-based Treatment for Distressed Caregivers of Persons With Moderate Dementia
Status: NOT_YET_RECRUITING
Conditions: Caregiver Burnout
Interventions: BEHAVIORAL: Health enSuite Caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19
Status: TERMINATED
Conditions: COVID-19|Yellow Fever
Interventions: DRUG: Galidesivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
Status: NOT_YET_RECRUITING
Conditions: Treatment Resistant Depression|Chronic Pain
Interventions: DRUG: Psilocybin 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle
Status: COMPLETED
Conditions: Pain|Sprains and Strains|Sprain
Interventions: DRUG: valdecoxib|DRUG: diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Self-Management of Breast and Nipple Pain With Technology (PROMPT) for Breastfeeding Women Study
Status: COMPLETED
Conditions: Breastfeeding, Exclusive|Pain, Acute|Maternal Distress|Parent-Child Relations|Self Efficacy
Interventions: BEHAVIORAL: The BSM Intervention|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of RAD1901 in the Treatment of Vasomotor Symptoms in Postmenopausal Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: RAD1901|DRUG: RAD1901|DRUG: RAD1901|DRUG: RAD1901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprolotherapy With Physical Therapy for Treatment of Patellar Chondromalacia
Status: COMPLETED
Conditions: Chondromalacia Patellae
Interventions: PROCEDURE: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Pediatric Formulations to Treat HIV Infection
Status: UNKNOWN
Conditions: HIV|AIDS
Interventions: DRUG: Epivir®, Retrovir® and Viramune®|DRUG: Lamivudine, Zidovudine and nevirapine|DRUG: Lamivudine, zidovudine, nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of New Head-mounted Visual Aids Among Patients With Low Vision
Status: NOT_YET_RECRUITING
Conditions: Glaucoma|Age-related Macular Degeneration|Retinitis Pigmentosa|Diabetic Retinopathy
Interventions: DEVICE: New head-mounted visual aids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bone Marrow-sparing Intensity-Modulated Radiotherapy to GI Cancer
Status: UNKNOWN
Conditions: Rectal Cancer|Gastric Cancer|Bone Marrow Toxicity|Adverse Effect of Radiation Therapy
Interventions: RADIATION: Bone Marrow-sparing Intensity-Modulated Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of MediYoga on Sleep Quality, Blood Pressure, and Quality of Life in Older Adults With Hypertension:
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Quality of Life|Quality of Sleep|Mental Health
Interventions: BEHAVIORAL: Intervention group I, Yoga 20 minuts x2 pr week|BEHAVIORAL: Intervention Group II, Yoga 40 minuts x2 pr week|OTHER: Control Group, No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Immunotherapy in Patients Sensitized to Dermatophagoides Pteronyssinus (DPT)
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: subcutaneous immunotherapy with DPT extract|BIOLOGICAL: Subcutaneous depot placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Protective Efficacy of Diff Strengths of Human Rotavirus Vaccine After Admn of 2 Doses to Infants Aged 2 Months
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: HRV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Trial to Study the Benefit of Colchicine in Patients With COVID-19
Status: COMPLETED
Conditions: COVID19
Interventions: DRUG: Colchicine Tablets|DRUG: Standard therapy for COVID-19 according to the stablished hospital protocols.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study Amifampridine Phosphate in Lambert-Eaton Myasthenic Syndrome (LEMS),Congenital Myasthenic Syndrome
Status: NO_LONGER_AVAILABLE
Conditions: Congenital Myasthenic Syndrome|Lambert-Eaton Myasthenic Syndrome|Nystagmus, Acquired
Interventions: DRUG: Amifampridine Phosphate
Study Type: EXPANDED_ACCESS
Clinical trial: Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis
Status: COMPLETED
Conditions: Perforated Appendicitis
Interventions: DRUG: 5 days of IV antibiotics (ceftriaxone and metronidazole)|DRUG: Home with oral antibiotics when eating (ampicillin/clavulanic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula for Safe Apnea
Status: COMPLETED
Conditions: Anesthesia, General|Apnea
Interventions: DEVICE: High flow nasal cannula|DEVICE: Buccal oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Normal Saline Flushing With And Without Heparin Lock In Maintaining Small Bore Intercostal Chest Catheter (ICC) Patency
Status: RECRUITING
Conditions: Pleural Effusion
Interventions: DRUG: Heparin saline lock|OTHER: Without heparin saline lock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety to Evaluate the Efficacy and Safety of HIP1601 in Patients With Non Erosive Reflux Disease
Status: COMPLETED
Conditions: Non-erosive Gastroesphageal Reflux Disease
Interventions: DRUG: HIP1601|DRUG: HGP1805
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Peritoneal Malignancy|Ovarian Cancer|Rectum Cancer|Appendix Cancer|Colon Cancer
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
Status: RECRUITING
Conditions: HPV Infections|Cervical Cancer|Vulvar Cancer|Vaginal Cancer|CIN1|CIN2|CIN 3|VaIN1|VaIN2|VaIN3|Genital Wart|VIN 1|VIN 2|VIN 3|AIS
Interventions: BIOLOGICAL: 9-valent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy
Status: UNKNOWN
Conditions: Cancer|Chemotherapy Effect|Fatigue|Quality of Life|Rumination|Alexithymia
Interventions: BEHAVIORAL: Art based mandala
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Perfusion|Bone Marrow|Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: Clinical evaluation|DIAGNOSTIC_TEST: Radiology|DIAGNOSTIC_TEST: Dynamic contrast-enhanced magnetic resonance imaging|DIAGNOSTIC_TEST: Evaluation of histological status
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulation of the Surgical Inflammatory Response by Etoricoxib
Status: TERMINATED
Conditions: Pain|Osteoarthritis, Hip|Postoperative Pain
Interventions: DRUG: Etoricoxib 60 mg|DRUG: Placebo for Etoricoxib 60 mg|DRUG: Etoricoxib 60 mg|DRUG: Placebo for Etoricoxib 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800, an Inhibitor of the Heat Shock Protein HSP90
Status: UNKNOWN
Conditions: Acute T Lymphoblastic Leukemia (T-ALL)|Acute B Lymphoblastic Leukemia (B-ALL)
Interventions: DRUG: injection of BEP 800|OTHER: Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Effect of 14 Days Dosing With Darapladib (SB-480848) on Carotid Plague Composition in Patients With Planned Carotid Endarterectomy
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: SB-480848 40 mg|DRUG: SB-480848 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of the Best Evidence of Neonatal Individualized Developmental Care Assessment Program (NIDCAP) in Very Low Birth Weight Infant (VLBWI)
Status: COMPLETED
Conditions: NIDCAP
Interventions: BEHAVIORAL: NIDCAP care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
Status: RECRUITING
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Hypofractionated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Parameterization, and Mechanism of Transcranial Focused Ultrasound
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Focused Ultrasound Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetic Profile of Ascending Oral Doses of MMV390048, Part A
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: MMV390048 40 mg|DRUG: Placebo to match MMV390048 40 mg|DRUG: MMV390048 80 mg|DRUG: Placebo to match MMV390048 80 mg|DRUG: MMV390048 120 mg|DRUG: Placebo to match MMV390048 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IZN-6N4 Oral Rinse for the Prevention of Oral Mucositis in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: IZN-6N4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION