pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Durvalumab + SoC chemotherapy|OTHER: Placebo + SoC chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for the Latarjet Procedure.
Status: COMPLETED
Conditions: Anterior Shoulder Instability
Interventions: DRUG: Tranexamic Acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Therapy Plus Maintenance Pharmacotherapy for Treating Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Interpersonal Social Rhythm Therapy (IPSRT)|BEHAVIORAL: Clinical Status and Symptom Response Therapy (CSSRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tecar in Addition of Functional Massage in Post-stroke Spasticity
Status: COMPLETED
Conditions: Stroke Sequelae|Massage|Spasticity, Muscle|Electrotherapy
Interventions: DEVICE: Tecar Therapy|DEVICE: Sham Tecar Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Postoperative Sore Throat After Thyroidectomy
Status: COMPLETED
Conditions: Post Operative Sore Throat
Interventions: DRUG: dexmedetomidine infusion group|DRUG: remifentanil infusion group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Combined exercise training|OTHER: Task-oriented training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation
Status: UNKNOWN
Conditions: Aphasia|Stroke
Interventions: DEVICE: anodal tDCS|DEVICE: cathodal tDCS|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Status: RECRUITING
Conditions: Central Nervous System Nongerminomatous Germ Cell Tumor|Choriocarcinoma|Embryonal Carcinoma|Immature Teratoma|Malignant Teratoma|Mixed Germ Cell Tumor|Pineal Region Germ Cell Tumor|Pineal Region Immature Teratoma|Pineal Region Yolk Sac Tumor|Suprasellar Germ Cell Tumor
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Ifosfamide|PROCEDURE: Magnetic Resonance Imaging|DRUG: Mesna|BIOLOGICAL: Pegfilgrastim|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|RADIATION: Radiation Therapy|PROCEDURE: Second-Look Surgery|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
Status: COMPLETED
Conditions: Sciatica|Spinal Stenosis of Lumbar Region|Degeneration of Lumbar or Lumbosacral Intervertebral Disc
Interventions: DRUG: prolotherapy solution of 20% dextrose|DRUG: Epidural Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Phase I/II Trial to Assess the Safety and Antiviral Effects of Escalating Doses of A Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Viremia and/or Viruria
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections
Interventions: DRUG: Sevirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection
Status: COMPLETED
Conditions: Healthcare Associated Infection|Clostridium Difficile Infection|Infection Due to Multidrug Resistant Bacteria
Interventions: DEVICE: Pulsed xenon ultraviolet (PX-UV) Device|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Memory and Thinking Skills Workshop to Improve Cognition in Gynecologic and Breast Cancer Survivors With Cognitive Symptoms
Status: COMPLETED
Conditions: Breast Carcinoma|Cancer Survivor|Cognitive Side Effects of Cancer Therapy|Malignant Female Reproductive System Neoplasm
Interventions: OTHER: Cognitive Intervention|OTHER: Educational Intervention|PROCEDURE: Functional Magnetic Resonance Imaging|OTHER: Memory Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Peri Implant Soft Tissue Healing in Single Implant Restoration Using Two Different Techniques
Status: COMPLETED
Conditions: Oral Soft Tissue Conditions
Interventions: DEVICE: augmentation procedure with Bio-Oss® and Bio-Gide®|PROCEDURE: augmentation procedure with connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Exercise Promotion in Primary Care
Status: UNKNOWN
Conditions: PreDiabetes|Diabetes|Sedentary Behavior
Interventions: BEHAVIORAL: Telephone-based motivational interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Multi-Center Randomized Study for Evaluating the EVAHEART®2 Left Ventricular Assist System
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: EVAHEART Left Ventricular Assist System (LVAS)|DEVICE: HeartMate 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Adjunctive Therapies
Status: COMPLETED
Conditions: Gingival Recession|Gingival Recession, Generalized
Interventions: PROCEDURE: Control|PROCEDURE: antimicrobial photodynamic therapy|PROCEDURE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Osteoimmune Interactions Linking Inflammation and Bone Destruction in Aggressive Periodontitis
Status: TERMINATED
Conditions: Aggressive Periodontitis|Chronic Periodontitis
Interventions: OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Blood Endothelium Biomarkers to Predict Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Atherosclerosis|Percutaneous Coronary Intervention|Cardiovascular Diseases
Interventions: OTHER: Data private hospitals, angioplasty, sampling of blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Approach in Ultrasound Guided Central Venous Catheterizations
Status: RECRUITING
Conditions: Central Venous Catheterization
Interventions: PROCEDURE: Short axis out of plane|PROCEDURE: Anteroposterior short axis in plane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Support for Caregivers of Older Adults With Cognitive Decline
Status: COMPLETED
Conditions: Caregiver Burden|Depression|Confidence, Self|Cognition|Fatigue|Function
Interventions: BEHAVIORAL: Occupational Therapy support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiolabeled Monoclonal Antibody, Cyclophosphamide, and Total Body Irradiation Followed By Donor Stem Cell Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: iodine I 131 monoclonal antibody BC8|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
Status: RECRUITING
Conditions: Arachnophobia|Cynophobia|Ophidiophobia
Interventions: BEHAVIORAL: Telemedicine Exposure Therapy Using Photos and Videos|BEHAVIORAL: Telemedicine-Based Virtual Reality Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of LY2409021 on the Electrical Impulses of the Heart
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2409021|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduced-dose Versus Standard Dose Radiotherapy for Nasopharyngeal Carcinomain
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: IMRT|DRUG: induction chemotherapy|DRUG: cisplatin concurrent chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Levetiracetam in Partial Seizures Control, With or Without Secondary Generalization
Status: COMPLETED
Conditions: Epilepsy|Partial Seizures
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growing Healthy Hearts: A Pilot Randomized Control Trial to Test Gardening as an Intervention to Improve Health
Status: WITHDRAWN
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Gardening and Nutrition Advice|BEHAVIORAL: Nutrition Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ostomy Primary Closure With 0.1% Betaine/0.1% Polyhexanide Wound Irrigation Compared to Pursestring Closure
Status: RECRUITING
Conditions: Surgical Site Infection|Wound Surgical|Colorectal Disorders
Interventions: DRUG: Primary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation|PROCEDURE: Pursestring Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Ibrutinib|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study To Investigate The Pharmacokinetics and Safety Of Dalbavancin In Hospitalized Children Aged 3 Months to 11 Years.
Status: COMPLETED
Conditions: Bacterial Infections.
Interventions: DRUG: Dalbavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Persistent Whiplash Associated Disorders.
Status: ACTIVE_NOT_RECRUITING
Conditions: Whiplash Injuries
Interventions: BEHAVIORAL: Values-based Cognitive Behavioral Therapy (V-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combining Mobilization With Movement and Spencer's Technique in Diabetic Adhesive Capsulitis Patients
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Mulligan's Mobilization with movement|OTHER: Spencer's muscle energy technique|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Acetyl-L-Carnitine In Severe Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy (Grade 3 of the West Haven Grading Scale)
Interventions: DRUG: Acetyl-l-Carnitine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Gemcitabine, Oxaliplatin and Radiotherapy in Treating Patients With Completely Resected Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|PROCEDURE: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis
Status: WITHDRAWN
Conditions: Adenomyosis|Heavy Uterine Bleeding|Dysmenorrhea
Interventions: DRUG: Ulipristal Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of rhPro-UK in Patients With Acute Ischaemic Stroke in 4.5 Hours After Stroke Onset(PROST)
Status: COMPLETED
Conditions: Acute Ischaemic Stroke
Interventions: DRUG: Recombinant human urokinase|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.
Status: COMPLETED
Conditions: Esketamine|Pregabalin|Acute Postoperative Pain|Neurosurgical Procedures|Perioperative Complication|Spinal Cord Neoplasms
Interventions: DRUG: S-ketamine and pregabalin|DRUG: Normal saline and placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1701 With or Without Famitinib in Patients With Advanced or Metastatic NSCLC
Status: WITHDRAWN
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: SHR-1701，Famitinib|DRUG: SHR-1701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Triptolide Woldifii for Autosomal Dominant Polycystic Kidney Disease
Status: TERMINATED
Conditions: Polycystic Kidney
Interventions: DRUG: tripterygium wilfordii|DRUG: Emodin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibition of Sterile Inflammation by Digoxin
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DRUG: Digoxin|OTHER: Placebo|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Emesis Control Study in Non-Hodgkin Lymphoma Patients Receiving R-CHOP
Status: WITHDRAWN
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Standard anti-emetics in conjunction with R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Activity of Lonafarnib and Docetaxel (Study P04467AM1)(TERMINATED)
Status: TERMINATED
Conditions: Prostate Cancer|Breast Cancer|Ovarian Cancer|Lung Cancer|Gastric Cancer
Interventions: DRUG: Docetaxel plus lonafarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Crovalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PreDiction and Validation of Clinical CoursE of Coronary Artery DiSease With CT-Derived Non-Invasive HemodYnamic Phenotyping and Plaque Characterization (DESTINY Study)
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Ischemic Heart Disease
Interventions: DIAGNOSTIC_TEST: CCTA-derived high risk plaque characteristics|DIAGNOSTIC_TEST: CFD-derived hemodynamic parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity
Status: RECRUITING
Conditions: Drug Toxicity
Interventions: COMBINATION_PRODUCT: Acetaminophen and Nicotinamide Riboside|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotoxin Therapy in Treating Patients With Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: cintredekin besudotox|DRUG: isolated perfusion|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: DISCOVERY: Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancies|Lymphoma|Multiple Myeloma|Leukemia|Blood Cancers
Interventions: BEHAVIORAL: Preference Reporting to Improve Management and Experience (PRIME)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PReoperative Chemoradiation (Paclitaxel-carboplatin or FOLFOX) for Resectable Esophageal and Junctional Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms|Gastro-esophageal Junction Cancer
Interventions: DRUG: FOLFOX|DRUG: CarboP-pacliT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance
Status: COMPLETED
Conditions: Diabetic Kidney Disease|Type 1 Diabetes|Diabetes|Diabetes Mellitus|Diabetes Complications|Diabetic Nephropathies|Type1diabetes|Diabetes, Autoimmune|Autoimmune Diabetes|Juvenile Diabetes|Type 1 Diabetes Mellitus
Interventions: DRUG: Aminohippurate Sodium Inj 20%|DRUG: Iohexol Inj 300 milligrams/milliliter (mg/ml)|RADIATION: PET/CT Scan|PROCEDURE: Renal Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracranial Pressure and Brain Function: Effects of Head Down Tilt Upon Brain Perfusion and Cognitive Performance
Status: COMPLETED
Conditions: Intracranial Hypertension
Interventions: OTHER: 12° head down tilt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Cardiac Surgery Patients
Status: COMPLETED
Conditions: Obesity|Hyperoxia|Hypercapnia
Interventions: OTHER: FreeO2|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Ticagrelor Monotherapy After Primary Percutaneous Coronary Intervention for ST-elevation Myocardial Infarction and the Effect on Intramyocardial Haemorrhage
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: DRUG: Ticagrelor|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adequacy and Efficacy of the e2TM Cervical Cell Collector Compared to Standard Spatula/CytoBrush Technique.
Status: COMPLETED
Conditions: Colposcopy|Biopsy
Interventions: DEVICE: e2 Cell Collector [SoftPAP(R)]|DEVICE: Spatula/Brush
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Controlled Study of Post-transplant Azacitidine for Prevention of Acute Myelogenous Leukemia and Myelodysplastic Syndrome Relapse (VZ-AML-PI-0129)
Status: COMPLETED
Conditions: Leukemia|AML|MDS
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pen-Administered Low-Dose Dasiglucagon for Prevention and Treatment of Hypoglycemia in People With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DRUG: Dasiglucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Silibinin|DRUG: Silibinin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Safety and Tolerability of TC-5214 Following Oral Administration of Multiple Doses for up to 8 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TC-5214|DRUG: TC-5214|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restoration of Permanent Molars Affected With Molar-incisor-hypomineralization (MIH) Among a Group of Egyptian Children Using Composite Restorations or Preformed Metal Crowns
Status: UNKNOWN
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: restoration of permanent molars affected with MIH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Hypnosis Improve Severe Sleepwalking ?
Status: COMPLETED
Conditions: Sleepwalking
Interventions: BEHAVIORAL: Hypnosis plus relaxation|BEHAVIORAL: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPB for Arthroscopic Hip Surgery
Status: NOT_YET_RECRUITING
Conditions: Acute Pain|Opioid Use
Interventions: PROCEDURE: Circum-psoas Block|PROCEDURE: Sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Strength Outcomes After Use of the PrimusRS for Specificity of Training in a Cardiac Rehabilitation Setting
Status: COMPLETED
Conditions: Coronary Artery Disease|Valve Disease, Heart
Interventions: OTHER: Educational session with Keep Your Move in the Tube and PrimusRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Recurrent Glioblastoma With Fractionated Radiotherapy Combined With Cadonilimab
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: RADIATION: fractionated radiotherapy|DRUG: cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of General Anesthesia Using Dexmedetomidine With Sevoflurane in Patients Undergoing Arthroscopic Shoulder Surgery: Preliminary Study
Status: COMPLETED
Conditions: Arthroscopic Shoulder Surgery in the Beach-chair Position
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy in Treating Patients With Stage III, Stage IV, or Relapsed Non-Small Cell Lung Cancer Treated With First-Line Chemotherapy
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Ad100-gp96Ig-HLA A1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: cryoablation|DRUG: Sintilimab|DRUG: lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Long-term Effects Secondary to Cancer Therapy in Children|Neurotoxicity|Psychosocial Effects of Cancer and Its Treatment|Radiation Toxicity
Interventions: DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Antibody-Drug Conjugate MYTX-011 in Subjects With Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: NSCLC|NSCLC Stage IV|NSCLC Stage IIIB|Non-Small Cell Lung Cancer|Advanced Non-Small Cell Squamous Lung Cancer|Advanced Non-Small Cell Lung Cancer|Advanced Non-Small Cell Non-Squamous Lung Cancer
Interventions: DRUG: MYTX-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Wireless Monitoring for Patients in the Internal Medicine UOC. Randomized Controlled Trial (GreenLineH-T)
Status: COMPLETED
Conditions: Hospitalization
Interventions: DEVICE: continuous wireless monitoring system of Vital Signs (Win@Hospital) + continuous system for continuous monitoring of blood sugar (Dexcom G6)(only for diabetic patients)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-inflammatory Effects of GTS-21 After LPS
Status: COMPLETED
Conditions: Endotoxemia|Sepsis|Vagal Activity
Interventions: DRUG: GTS-21, [3-(2,4-dimethoxybenzylidene)-anabaseine dihydrochloride]|DRUG: Placebo|DRUG: Lipopolysaccharide E. Coli 113:H 10:K negative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction
Status: COMPLETED
Conditions: Pulmonary; Hypertension|Heart Failure|Preserved Ejection Fraction
Interventions: DRUG: 15N Nitrate|DRUG: 14N Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of ICD Electrograms During Ventricular Tachycardia Ablation
Status: COMPLETED
Conditions: Sustained Monomorphic Ventricular Tachycardia
Interventions: PROCEDURE: Conventional RF catheter ablation|PROCEDURE: Investigational RF Catheter Ablation using ICD-EG information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: "Grab-and-Go" meal plan|OTHER: "Jump-Start" meal plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection
Status: COMPLETED
Conditions: Onchocerciasis
Interventions: DRUG: 2 mg moxidectin|DRUG: ivermectin 150 mcg/kg|DRUG: 4 mg moxidectin|DRUG: 8 mg moxidectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients
Status: UNKNOWN
Conditions: Fiberoptic Bronchoscopy (FOB)|Bronchoalveolar Lavage (BAL)|Respiratory Disease
Interventions: PROCEDURE: Fiberoptic Bronchoscopy (FOB)|PROCEDURE: Bronchoalveolar Lavage (BAL)|DIAGNOSTIC_TEST: Electrical Impedance Tomography (EIT)|DIAGNOSTIC_TEST: Arterial Blood Gas test (ABG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Abdominal Exercise Programs on the Interrect Distance
Status: COMPLETED
Conditions: Postpartum Period
Interventions: OTHER: Classic abdominal strengthening exercises|OTHER: Hypopressive abdominal exercises program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DRUG: sapropterin dihydrochloride|DRUG: Moxifloxacin|DRUG: Moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Physical Activity on Neurogenesis in Peripheral Diabetic Neuropathy Type-II Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type II Diabetes Mellitus With Neurological Manifestations
Interventions: BEHAVIORAL: Phsical Activity|DRUG: Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: "Sweet Expectation and Positive Thinking" the Use of the Mandala in the Induction of Labor
Status: RECRUITING
Conditions: Nulliparity|Induction of Labor Affected Fetus / Newborn
Interventions: OTHER: Mandala|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke.
Status: RECRUITING
Conditions: Stroke|Upper Extremity Paresis
Interventions: DEVICE: Exoskeleton-Assisted Upper Limb Rehabilitation|OTHER: Traditional Upper Limb Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Novel NMDA NR2B-Subtype Selective Antagonist, EVT 101, on Brain Function
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DRUG: EVT 101|DRUG: EVT 101|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visual Function and Patient Satisfaction After Bilateral Implantation of AcrySof Natural ReSTOR (Model SN60D3) or AcrySof Natural Monofocal (Model SN60AT)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Acrysof Natural ReSTOR SN60D3|DEVICE: Acrysof Natural Monofocal SN60AT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine for the Prevention of Intravesical Recurrence of Urothelial Cancer in Patients With Upper Urinary Tract Urothelial Cancer Undergoing Radical Nephroureterectomy, GEMINI Study
Status: TERMINATED
Conditions: Stage 0a Renal Pelvis and Ureter Cancer AJCC v8|Stage 0a Renal Pelvis Cancer AJCC v8|Stage 0a Ureter Cancer AJCC v8|Stage 0is Renal Pelvis and Ureter Cancer AJCC v8|Stage 0is Renal Pelvis Cancer AJCC v8|Stage 0is Ureter Cancer AJCC v8|Stage I Renal Pelvis and Ureter Cancer AJCC v8|Stage I Renal Pelvis Cancer AJCC v8|Stage I Ureter Cancer AJCC v8|Stage II Renal Pelvis and Ureter Cancer AJCC v8|Stage II Renal Pelvis Cancer AJCC v8|Stage II Ureter Cancer AJCC v8|Stage III Renal Pelvis and Ureter Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage IV Renal Pelvis and Ureter Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8
Interventions: DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic and Tolerance Study of TQ-A3326 in Healthy Participants.
Status: UNKNOWN
Conditions: Pharmacokinetic
Interventions: DRUG: TQ-A3326|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Incidence of Infection After Total Knee Arthroplasty Using an Erythromycin and Colistin Loaded Cement or a Standard Cement
Status: COMPLETED
Conditions: Infection After Primary Total Knee Arthroplasty
Interventions: PROCEDURE: Cement without antibiotic.|PROCEDURE: Cement with erytromycin and colistin.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Sinusitis|Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: LYR-210|DRUG: Sham procedure control|OTHER: Background Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation
Status: UNKNOWN
Conditions: Aortic Aneurysm|Iliac Aneurysm|Stenoses, Aortic|Iliac Artery Stenosis
Interventions: PROCEDURE: Aorto-iliac endovascular procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders.
Status: TERMINATED
Conditions: Chronic Myeloid Leukemia (CML)|Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)|Other Glivec/Gleevec Indicated Hematological Disorders (HES, CEL, MDS/ MPN)
Interventions: DRUG: Gleevec/Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Oxalate-Driven Host Responses in Kidney Stone Disease
Status: RECRUITING
Conditions: Kidney Stones
Interventions: DIETARY_SUPPLEMENT: Low Oxalate Diet|DIETARY_SUPPLEMENT: High Oxalate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Switch From Dual Regimens Based on Dolutegravir Plus a Reverse Transcriptase Inhibitor to E/C/F/TAF in Virologically Suppressed, HIV-1 Infected Patients (Be-OnE)
Status: TERMINATED
Conditions: HIV-1-infection
Interventions: DRUG: Genvoya 150Mg-150Mg-200Mg-10Mg Tablet|DRUG: Dolutegravir 50 mg plus one RTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anabolic Potential of 3-hydroxybutyrate (3-OHB) and Whey Protein in a Human Catabolic Inflammatory Disease Model
Status: COMPLETED
Conditions: Endotoxemia|Muscle Loss|Catabolic State|Protein; Disease|Nutrition Therapy
Interventions: DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: 3-OHB + Whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radial Shock Waves for Functional Disability in Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Active Radial Shockwave|DEVICE: Sham Radial Shockwave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Human Dehydrated Umbilical Cord Allograft in Supraspinatus Tendon Repair
Status: COMPLETED
Conditions: Shoulder Injury|Shoulder Sprain|Supraspinatus Tear
Interventions: OTHER: Human dehydrated umbilical cord allograft|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Regimen to Prevent Malaria and STI in Pregnant Women With HIV
Status: COMPLETED
Conditions: HIV|Pregnancy Malaria|Sexually Transmitted Infection
Interventions: DRUG: Azithromycin/TMPS|DRUG: Placebo/TMPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Glidesheath Slender to Reduce Radial Artery Occlusion Following 7 French Transradial Coronary Intervention
Status: UNKNOWN
Conditions: Radial Artery Occlusion|Coronary Artery Disease
Interventions: DEVICE: 7-Fr Glidesheath Slender|DEVICE: Cordis 7-Fr radial sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the AudibleHealth Dx AI/ML-Based Dx SaMD Using FCV-SDS in the Diagnosis of COVID-19 Illness: Clinical Validation
Status: COMPLETED
Conditions: 2019 Novel Coronavirus Disease|2019 Novel Coronavirus Infection|2019-nCoV Disease|COVID-19 Pandemic|COVID-19 Virus Disease|COVID-19 Virus Infection|Coronavirus Disease 2019|Coronavirus Disease-19|SARS-CoV-2 Infection
Interventions: DEVICE: Diagnostic Test: Diagnostic Software as Medical Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Kinesiotaping vs.Auricular Therapy in Primary Dysmenorrhoea.
Status: COMPLETED
Conditions: Primary Dysmenorrhoea
Interventions: PROCEDURE: Auricular therapy|PROCEDURE: kinesio tape|PROCEDURE: Auricular therapy Placebo group|PROCEDURE: kinesio tape Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Ultrasound Detection of Lipohypertrophy to Improve Glycemic Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Lipohypertrophy
Interventions: PROCEDURE: LH Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Home Based Electrical Stimulation on Post-stroke Lower Limb Tightness.
Status: UNKNOWN
Conditions: Spasticity as Sequela of Stroke
Interventions: OTHER: Feasibility and Impact of Home-based Electrical Stimulation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Luma Light System Proof of Concept Study in Subjects With Mild to Moderate Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DEVICE: Luma Light System|DEVICE: Luma Light|DEVICE: Occlusive Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Vitamin D Reduce Risk of Developing Type II DM in High Risk Individuals
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients
Status: UNKNOWN
Conditions: Septic Shock|Anesthesia
Interventions: DRUG: Ketamine full dose|DRUG: Ketamine half dose|DRUG: Lidocaine|DRUG: Midazolam|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy Versus Benzydamin in Prevention and Treatment of Oral Mucositis
Status: COMPLETED
Conditions: Stomatitis (Oral Mucositis)
Interventions: DRUG: 0.15% bezaydamine hydrochloride.|DEVICE: low power laser with a wavelength of 870 nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Anemia|Myelodysplastic Syndrome
Interventions: DRUG: Deferasirox|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Policaptil Gel Retard® in Overweight and Mild Obese Subjects
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DEVICE: Libramed|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Characteristics, Associated Factors, and Clinical Outcomes of Prescribing Encorafenib and Binimetenib Versus Dabrafenib and Trametinib Among BRAF v600 Mutated Metastatic Melanoma Patients
Status: COMPLETED
Conditions: BRAF v600 Mutated Metastatic Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma
Status: COMPLETED
Conditions: N-Ras Mutated Locally Advanced or Metastasis Malignant Cutaneous Melanoma
Interventions: DRUG: Pimasertib|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Barriers to Physical Activity in Patients With Cognitive, Neuromotor or Sensory Impairments During Aging
Status: RECRUITING
Conditions: Disability or Chronic Disease Leading to Disablement
Interventions: OTHER: standard of care for patients with cognitive impairments|OTHER: standard of care for patients with neuromotor impairments|OTHER: standard of care for patients with sensory impairments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Simulation-based Training on Confidence and Competence in Obtaining Vitals in a Child With Autism
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Educational Intervention: online didactic lecture and educational simulation activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pulsed Short Wave Therapy In Cesarean Section
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DEVICE: RecoveryRx|DEVICE: Sham RecoveryRx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Ultra-Rapid-Acting Insulin Lispro (URAL) in Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: URAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Supplement of Agave Tequilana Weber Azul vs Psyllium Plantago in Patients With Functional Constipation
Status: UNKNOWN
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Agave Fructans 5 g|DIETARY_SUPPLEMENT: Agave Fructans 10 g|DIETARY_SUPPLEMENT: Agave Fructans 5 g + Maltodextrin 10 g|DIETARY_SUPPLEMENT: Psyllium plantago
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria
Status: TERMINATED
Conditions: Viruria|Viremia
Interventions: DRUG: Leflunomide and orotic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PET Imaging With Tc-94m Sestamibi to Assess Resistance to Chemotherapy
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Tariquidar|DRUG: Tc-94m Sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC