pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage
Status: TERMINATED
Conditions: Cerebral Ischemia|Subarachnoid Hemorrhage
Interventions: OTHER: Induced hypertension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial
Status: COMPLETED
Conditions: Pain, Postoperative|Irreversible Pulpitis|Apical Periodontitis
Interventions: DEVICE: EdgeEndo x7 continuous rotation files|DEVICE: EdgeOne Fire reciprocating files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of AloeVera Gel Gum Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients
Status: UNKNOWN
Conditions: CHRONIC PERIODONTITIS
Interventions: PROCEDURE: Tooth Brushing|PROCEDURE: aloe vera Massaging|PROCEDURE: SRP with aloe vera massaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alveolar Ridge Preservation Using Amniotic Chorion Membrane
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Ridge Preservation
Interventions: OTHER: Amniotic Chorion Membrane and Bio-Oss xenograft|OTHER: Amniotic Chorion Membrane only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring Initiation at Hospital Discharge
Status: TERMINATED
Conditions: Type 1 Diabetes|Type2 Diabetes|Hyperglycemia|Hypoglycemia|Hypoglycemia Unawareness
Interventions: DEVICE: CGM4Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Ramosetron on Post-discharge Nausea and Vomiting
Status: UNKNOWN
Conditions: Hysteroscopy
Interventions: DRUG: Ramosetron|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modified Sternal Precautions Versus Conventional Sternal Precautions in Physical Function After Sternotomy
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Modified sternal precautions|OTHER: Conventional sternal precautions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness of Corifollitropin α as Alternative to Conventional Daily rFSH Protocols in Oocyte Donors Undergoing Pituitary Suppression With Medroxiprogesterona Acetate (MPA)
Status: NOT_YET_RECRUITING
Conditions: Infertility, Female|Reproductive Sterility
Interventions: DRUG: Corifolitropin Alfa|DRUG: Folitropin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Supplement Prosta-OK® Neo as an Adjunct Therapy in Patients With Mild to Severe Non-neurogenic Male Lower Urinary Tract Symptoms Receiving Tamsulosin Therapy
Status: UNKNOWN
Conditions: Lower Urinary Tract Symptoms
Interventions: DIETARY_SUPPLEMENT: Prosta-OK® Neo or Prosta-OK® Neo-matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Oral Hygiene on Local Wound and Systemic Infection in Patients With Percutaneous Endoscopic Gastrostomy Placement
Status: UNKNOWN
Conditions: Dysphagia|Peristomal Wound Infection
Interventions: DRUG: Chlorhexidine gluconate 0.2%|OTHER: Plain water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Myeloproliferative Chronic Myelomonocytic Leukemia
Interventions: DRUG: Cladribine|DRUG: Cytarabine|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on Treating the First-episode Depression
Status: RECRUITING
Conditions: Depression
Interventions: OTHER: electroacupuncture (EA) treatment|OTHER: sham acupuncture (SA) treatment|DRUG: Escitalopram 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores.
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: severity of lung involvement with COVID-19.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Can Administration of Etamsylate Reduce Postpancreatectomy Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Postpancreatectomy Hemorrhage
Interventions: DRUG: Etamsylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Greater Occipital Nerve Block Versus Metoclopramide
Status: COMPLETED
Conditions: Migraine
Interventions: PROCEDURE: Greater occipital nerve block with bupivacaine|DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Non-invasive Non-oscillometric Blood Pressure Wristband
Status: COMPLETED
Conditions: Hypotension|Hypertension
Interventions: DEVICE: Non-invasive non-oscillometric blood pressure wristband device|DEVICE: Invasive intra-arterial blood pressure monitors.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients
Status: COMPLETED
Conditions: Dental Plaque|Gingivitis
Interventions: DEVICE: sonic toothbrush (Philips Sonicare® FlexCare, Typ HX6942/04)|DEVICE: manual toothbrush / interdental toothbrush (elmex® Inter X medium toothbrush / interdental brush Curaprox®)|DEVICE: manual toothbrush (elmex® Inter X medium toothbrush)|DEVICE: manual toothbrush (elmex® Inter X medium toothbrush)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of LAU-7b for the Treatment of Long COVID in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID
Interventions: DRUG: LAU-7b for 3 cycles|DRUG: LAU-7b for 1 cycle, then placebo|OTHER: Placebo for 3 cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
Status: RECRUITING
Conditions: Cardiovascular Risk|Chronic Kidney Disease|Inflammation
Interventions: DRUG: Ziltivekimab B|DRUG: Ziltivekimab C|DRUG: Placebo (Ziltivekimab B)|DRUG: Placebo (Ziltivekimab C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Real-world Study of Heptapopal Ethanolamine Tablets in Concurrent/Sequential Radioimmunoinduced Thrombocytopenia
Status: NOT_YET_RECRUITING
Conditions: Cancer, Therapy-Related
Interventions: DRUG: Herombopag Olamine Tablets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Device-based Rate Versus Rhythm Control in Symptomatic Recent-onset Atrial Fibrillation (RACE 9 OBSERVE-AF)
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: OTHER: Rate control|OTHER: Pharmacological or electrical cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of VNS in Epileptic Patients to Induce Cardioprotection
Status: COMPLETED
Conditions: Epilepsy|Sudden Cardiac Death
Interventions: OTHER: A change or titration in the current or frequency settings of the VNS therapy system.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biodiversity Interventions for Well-Being
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbial Colonization|Immune System Diseases|Well-Being, Psychological|Nature, Human
Interventions: OTHER: Rewilding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RubusElite Efficacy Testing of a Novel High Protein, Berry Polyphenol Enriched Dairy Beverage
Status: COMPLETED
Conditions: Muscle Damage|Muscle Soreness|Exercise Performance|Gut Microbiome|Stress|Anxiety
Interventions: DIETARY_SUPPLEMENT: RubusElite|DIETARY_SUPPLEMENT: 'Protein rich' dairy beverage|DIETARY_SUPPLEMENT: 'Low Protein' dairy beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetics of Clopidogrel in Acute Coronary Syndromes
Status: TERMINATED
Conditions: Acute Coronary Syndromes
Interventions: GENETIC: genetic tests for CYP2C19*2, CYP2C19*17 and ABCB1 3435|OTHER: clinical algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Paritaprevir With Ritonavir (ABT-450/r) When Given Together With Ombitasvir and With and Without Ribavirin (RBV) in Treatment-Naïve Participants With Genotype 1, 2 or 3 Chronic Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: ABT-450|DRUG: ABT-267|DRUG: ribavirin|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tipranavir and Ritonavir vs. Saquinavir and Ritonavir Used With Two Nucleoside Reverse Transcriptase Inhibitors in Single Protease Inhibitor-experienced HIV-1 Patients
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Tipranavir (TPV) low dose|DRUG: Tipranavir (TPV) high dose|DRUG: Ritonavir low dose|DRUG: Ritonavir high dose|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Sessions of Perineural Injection With Dextrose for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: two-sessions of ultrasound-guided PIT|PROCEDURE: One-sessions of ultrasound-guided PIT|PROCEDURE: Placebo ultrasound-guided injection with nerve hydrodissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Carbohydrase-inhibiting Polyphenols on Glycaemic Response in Vivo
Status: COMPLETED
Conditions: Hyperglycaemia
Interventions: OTHER: Reference food|OTHER: Test food dose 1|OTHER: Test food dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Probiotics and Oxytocin Nasal Spray on Social Behaviors of Autism Spectrum Disorder (ASD) Children
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: intranasal oxytocin|DIETARY_SUPPLEMENT: oral probiotics|DIETARY_SUPPLEMENT: oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Absolute Bioavailability of a Single Oral Dose of Ponesimod in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ponesimod 5mg i.v.|DRUG: Ponesimod i.v.|DRUG: Ponesimod 10 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Test the Safety and Efficacy of MK0249 in Patients With ADHD (0249-018)(COMPLETED)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)
Interventions: DRUG: MK0249|DRUG: Concerta (methylphenidate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Liposomal Doxorubicin With or Without Olaratumab (IMC-3G3) in Platinum-Refractory or Resistant Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: BIOLOGICAL: Olaratumab|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semiflex Assisted Vacuum Therapy for Perianal Abscesses/Sinuses and Fistula: a Pilot Study
Status: RECRUITING
Conditions: Perianal Fistula|Perianal Fistula Due to Crohn's Disease|Perianal Abscess
Interventions: DEVICE: Semiflex Dome Catheter System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine
Status: COMPLETED
Conditions: Unstable Angina Pectoris
Interventions: DRUG: Crushed ticagrelor followed by morphine|DRUG: Crushed ticagrelor, morphine,metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-Blockers in Allergic Rhinitis (MAN 01)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Doxazosin XL|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Higher Dose Intradermal H5 Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated Influenza A Vaccine A/H5N1|BIOLOGICAL: Inactivated Influenza A Vaccine A/H5N1|DRUG: Placebo (IM)|DRUG: Placebo (ID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study 102: Multiple Ascending Dose Study of ALLN-346 (Engineered Urate Oxidase)
Status: COMPLETED
Conditions: Hyperuricemia|Gout
Interventions: DRUG: ALLN-346|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal
Status: COMPLETED
Conditions: Acute Bleeding on Long-Term Anticoagulation Therapy|Hemorrhage|Significant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time)|Urgent Reversal of Vitamin K Antagonist (VKA) Anticoagulation
Interventions: DRUG: 4-factor prothrombin complex concentrate (4FPCC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Instrument Assisted Soft Tissue Mobilization Techniques Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Instrument Assisted Soft Tissue Mobilization Group While Lying Prone|OTHER: Instrument Assisted Soft Tissue Mobilization Group Combined with Functional Movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Peramivir in Subjects With Uncomplicated Acute Influenza
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Peramivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Phase I Study to Evaluate the Safety, Efficacy and Dose Responses of Ronacaleret in Healthy Human Volunteers
Status: COMPLETED
Conditions: Bone Marrow Transplantation
Interventions: DRUG: Ronacaleret (100mg tablet)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reduced Side-Effects Of Photodynamic Therapy For The Treatment Of Moderate To Severe Acne (i-PDT)
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 20 % Aminolevulinic Acid|DEVICE: Red light only|DEVICE: Blue light only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Routine Care + Glycemic Excursion Minimization (RC+GEM)|OTHER: Routine Care (RC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect Subtalar Joint Pronation on Postural Stability and Lower Extremity Alignment
Status: COMPLETED
Conditions: Postural Stability|Dynamic Knee Valgus|Injury Prevention
Interventions: OTHER: Postural stability assessment|OTHER: Frontal plan prjection angle|OTHER: Foot and Ankle Ability Measure|OTHER: Navicular Drop Test|OTHER: Calcaneotibial Angle Measurement|OTHER: Tibial Torsion Angle|OTHER: Femoral internal and external rotation measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Influence of Endotracheal Tube Design on Fluid Leakage Into the Lungs During Surgery
Status: COMPLETED
Conditions: Respiratory Aspiration
Interventions: DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase III Study on HMPL-523 for Treatment of ITP
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Immune Thrombocytopenia (ITP)
Interventions: DRUG: HMPL-523|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Motivational Interviewing on Sleep Hygiene, Sleep Quality and Quality of Life
Status: RECRUITING
Conditions: Sleep Hygiene
Interventions: OTHER: Sleep hygiene education and motivational interviewing|OTHER: face-to-face sleep hygiene training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old.
Status: TERMINATED
Conditions: Seizures|Pneumococcal Meningitis
Interventions: DRUG: Phenytoin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Transcutaneous Electrical Nerve Stimulation Versus Capsicum Plaster on Emesis Gravidarum
Status: RECRUITING
Conditions: Emesis Pregnancy
Interventions: DEVICE: Transcutaneous electrical nerve stimulation|OTHER: Capsicum plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Response to Use of Intravesical Ozone Gas in Interstitial Cystitis /Bladder Pain Syndrome
Status: UNKNOWN
Conditions: Interstitial Cystitis, Chronic|Bladder Pain Syndrome
Interventions: DRUG: Ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors
Status: TERMINATED
Conditions: Recurrent Glioma|High-grade Meningioma|Brain Metastasis
Interventions: DRUG: Panobinostat|RADIATION: Stereotactic body radiation therapy|PROCEDURE: Quality-of-life assessment|RADIATION: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives
Status: TERMINATED
Conditions: Hematologic Malignancy|Leukemia|Acute Lymphoblastic Leukemia|ALL|Acute Myelogenous Leukemia|AML|Chronic Lymphocytic Leukemia|CLL|Lymphoma|Hodgkin's Lymphoma|Non-hodgkin's Lymphoma|Myeloma
Interventions: RADIATION: Total Body Irradiation (TBI)|BIOLOGICAL: Donor Lymphocyte Infusion (DLI)|DRUG: Cyclophosphamide (CY)|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil (MMF)|BIOLOGICAL: Hematopoietic Stem Cell Transplant (HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Versus Steroids and Cyclophosphamide in the Treatment of Idiopathic Membranous Nephropathy
Status: UNKNOWN
Conditions: Glomerulonephritis, Membranous
Interventions: DRUG: Rituximab|DRUG: Methylprednisolone|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4
Status: COMPLETED
Conditions: Tumors|Medical Oncology|Neoplasms
Interventions: DRUG: AGS-22M6E|DRUG: ASG-22CE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Drug Interaction Between CKD-519 and Rosuvastatin in Healthy Male Subjects
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Rosuvastatin 20 mg|DRUG: CKD-519 200 mg|DRUG: Rosuvastatin 20 mg & CKD-519 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Effects Of Different Exercise Approaches On Type 2 DM Women
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Blue Prescription Exercise Program|BEHAVIORAL: Video Based Home Exercise Program|BEHAVIORAL: Supervised Group Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Validation of a Digitalised Intraoral Protection
Status: RECRUITING
Conditions: Ventilatory Performances of Athletes During the Use of the Intra-oral Protections
Interventions: OTHER: Manufacture of custom-made IOP|OTHER: Ventilation tests|OTHER: Evaluation of comfort level:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units
Status: COMPLETED
Conditions: Critical Illness|Mechanical Ventilation Complication|Ventilator Associated Pneumonia
Interventions: DEVICE: tapered PVC-cuffed tracheal tubes|DEVICE: Standard PVC-cuffed tracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Change of HbA1c, Urinary Glucose Excretion and Other Factors in Patients Treated With Ipragliflozin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Oral administration of Ipragliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nab-Paclitaxel, Capecitabine, and Radiation Therapy Following Induction Chemotherapy in Treating Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma|Stage II Pancreatic Cancer AJCC v6 and v7|Stage IIA Pancreatic Cancer AJCC v6 and v7|Stage IIB Pancreatic Cancer AJCC v6 and v7|Stage III Pancreatic Cancer AJCC v6 and v7
Interventions: DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis|DRUG: Nab-paclitaxel|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy
Status: COMPLETED
Conditions: Autoimmune Autonomic Ganglionopathy (AAG)
Interventions: DRUG: Double blinded IVIg|OTHER: Double blinded Placebo|OTHER: Single Blinded IVIg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Booster Dose of a Quadrivalent Meningococcal Conjugate Vaccine in Children
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: MenACYW conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Not Taking Inhaled Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: lebrikizumab (MILR1444A)|DRUG: lebrikizumab (MILR1444A)|DRUG: lebrikizumab (MILR1444A)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracranial Artery Stenosis
Interventions: DEVICE: intracranial balloon angioplasty|DRUG: aggressive medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravitreal Conbercept With Modified Treat-and-Extend Regimens in Exudative AMD
Status: UNKNOWN
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: different degrees of adjustment of the injection interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zr-89 Cimzia PET Imaging Rheumatoid Arthritis
Status: SUSPENDED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: 89Zr-DFO-CZP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility Study of Enhanced MRI for Early Stage Non Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: OTHER: DCE-MRI scan|RADIATION: Stereotactic Body Radiation Therapy|OTHER: 4D-CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Interaction Study Between Rifabutin And Lersivirine (UK-453,061)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lersivirine|DRUG: Rifabutin|DRUG: Lersivirine|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.
Status: COMPLETED
Conditions: Significant Bleeding Risk
Interventions: DRUG: Octaplex|DRUG: Beriplex P/N (Kcentra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tocilizumab in Primary Sjögren's Syndrome.
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome (pSS)
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Identification and Nutritional Intervention of Primary Sarcopenia Based on Gut-muscle Axis
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: symbiotic|DIETARY_SUPPLEMENT: whey protein|DIETARY_SUPPLEMENT: symbiotic placebo|DIETARY_SUPPLEMENT: whey protein placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Panobinostat Monotherapy in Women With v-ERB-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (HER2) Positive Locally Recurrent or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Panobinostat - LBH589|DRUG: Panobinostat - LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET / MR With PSMA for Diagnosis and Staging of Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DIAGNOSTIC_TEST: PET MRI with PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket
Status: UNKNOWN
Conditions: Periodontitis, Localized Aggressive|Periodontal Diseases|Endodontic Disease|Endodontic Inflammation|Periodontal Pocket|Periodontal Inflammation|Periodontal Attachment Loss|Periodontal Bone Loss|Periodontitis
Interventions: DIAGNOSTIC_TEST: Orthopantomogram X-ray view|DIAGNOSTIC_TEST: Endo-Ice|DIAGNOSTIC_TEST: Electric Pulp Tester (EPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular Intervention
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Anti-platelets and statin|DRUG: alteplase|PROCEDURE: intra arterial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine and Face-to-face Consultations Diagnostic Accuracy Comparison in Gastrointestinal Infection Patients
Status: UNKNOWN
Conditions: Gastrointestinal Infection
Interventions: OTHER: Telemedicine Consultation|OTHER: Face-to-face Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Exenatide on Abdominal Fat Distribution in Patients With Type 2 Diabetes Pretreated With Metformin
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: placebo|DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Parenchymal Core Needle Biopsy
Status: COMPLETED
Conditions: Image-guided Biopsy|Complications|Kidney Glomerulus
Interventions: DEVICE: coaxial renal biopsy|DEVICE: noncoaxial renal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy of Fexuprazan for Prevention or Control of Gastritis Symptoms in Patients on Treatment With Systemic Steroids
Status: NOT_YET_RECRUITING
Conditions: Patients on Treatment With Systemic Steroids
Interventions: DRUG: Lansoprazole|DRUG: Fexuprazan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Apple Cider Vinegar in Type 2 Diabetics
Status: COMPLETED
Conditions: Randomized Controlled Trial|Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Apple Cider Vinegar and tablet Tagipmet (Metformin + Sitagliptin group)|OTHER: Water with Apple Cider vinegar flavor and tablet Tagipmet (Metformin + Sitagliptin group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Trial of Treatment for Disc Herniation With Radiating Leg Pain
Status: COMPLETED
Conditions: Radiating Leg Pain|Disc Protrusion
Interventions: DEVICE: Orthotrac Pneumatic Vest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Media Diversion in Improving Quality of Life in Patients With Recurrent Gynecologic Cancers Receiving Chemotherapy
Status: COMPLETED
Conditions: Female Reproductive Cancer
Interventions: PROCEDURE: mind-body intervention procedure|OTHER: survey administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Imatinib Mesylate With or Without Hydroxychloroquine in Treating Patients With Chronic Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: hydroxychloroquine|DRUG: imatinib mesylate|GENETIC: cytogenetic analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual Therapy on Shoulder Function
Status: COMPLETED
Conditions: Musculoskeletal Manipulations|Shoulder|Range of Motion|Muscle Strength|Surface Electromyography
Interventions: OTHER: Thoracic Manipulation|OTHER: Cervical Manipulation|OTHER: glenohumeral posterior glide mobilization|OTHER: Sleeper stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study on the VERAFEYE System
Status: NOT_YET_RECRUITING
Conditions: Atrial Septal Defect|Atrial Fibrillation|Atrial Arrhythmia|Left Atrial Appendage Closure
Interventions: DEVICE: VERAFEYE System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)
Status: COMPLETED
Conditions: Recurrence of Solid Tumor|Glioblastoma Multiforme|Melanoma
Interventions: DRUG: MK-4827|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Post Spinal Anesthesia Hypotension
Interventions: DRUG: Norepinephrine|DRUG: Midodrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Idasanutlin|DRUG: Cytarabine|DRUG: Daunorubicin|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AVP-786|DRUG: AVP-923
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Impact of NaHCO3- on Exercise Hyperpnea
Status: COMPLETED
Conditions: Pulmonary Ventilation
Interventions: DRUG: Sodium Bicarbonate|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Prehabilitation intervention|BEHAVIORAL: Health education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Autologous CD8+ Melanoma Specific T Cells|DRUG: Cyclophosphamide|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea.
Status: COMPLETED
Conditions: Exercise Training|Respiratory Muscle Training|High-Intensity Interval Training|Apnea
Interventions: OTHER: High intensity interval training|OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerosol Particle From EGD in Patients With and Without Head Box in COVID-19 Era
Status: COMPLETED
Conditions: EGD|Covid19|Aerosol Disease|Head Box
Interventions: DEVICE: Head box during upper gastrointestinal endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Study of New Limbal Ring Prototypes
Status: COMPLETED
Conditions: Cosmetic Effect
Interventions: DEVICE: etafilcon test contact lens Variant AP|DEVICE: etafilcon test contact lens Variant JG|DEVICE: etafilcon test contact lens Variant CS|DEVICE: etafilcon test contact lens Variant VC|DEVICE: etafilcon test contact lens Variant LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Twins Study of Gene Therapy for HIV Infection
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infection|Kaposi's Sarcoma
Interventions: DRUG: Syngeneic Lymphocytes (CD4+) Cultured with OKT3 (Ortho) and Interleukin-2 (Chiro
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of APP13007 to Treat Inflammation and Pain After Cataract Surgery
Status: COMPLETED
Conditions: Ocular Inflammation and Pain After Cataract Surgery
Interventions: DRUG: APP13007, 0.05%|DRUG: APP13007, 0.1%|DRUG: APP13007 Placebo, 0.05%|DRUG: APP13007 Placebo, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perforator Mapping and Optimizing Design of the Lateral Arm Flap
Status: RECRUITING
Conditions: Coverage of Soft Tissue Defects
Interventions: DIAGNOSTIC_TEST: coloured duplex|PROCEDURE: supra facial dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Finger-prick Autologous Blood (FAB) for Use in Dry Mouth
Status: UNKNOWN
Conditions: Xerostomia|Xerostomia Due to Radiotherapy|Xerostomia Due to Hyposecretion of Salivary Gland
Interventions: OTHER: Finger-prick Autologous Blood (FAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Calcium Phosphate Containing Desensitizer on Postoperative Sensitivity
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Calcium phosphate desensitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer|Carcinoma, Squamous Cell|Adenocarcinoma
Interventions: DRUG: AZD4547|DRUG: Vistusertib|DRUG: Palbociclib|DRUG: Crizotinib|DRUG: Selumetinib|DRUG: Docetaxel|DRUG: AZD5363|DRUG: Osimertinib|DRUG: Durvalumab|DRUG: Sitravatinib|DRUG: AZD6738
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Doxorubicin and Carboplatin in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of a Follow-On Formula Fed to Children From 36-48 Months of Age
Status: COMPLETED
Conditions: Acute Respiratory Infection|Diarrheal Disease
Interventions: DIETARY_SUPPLEMENT: Cow's milk|DIETARY_SUPPLEMENT: Follow-On Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Fusions Steroid Study
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Fusion
Interventions: DRUG: Dexamethasone injection|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Alzheimer Proteomics
Status: TERMINATED
Conditions: Probable Alzheimer Disease|Parkinson Disease|Neurological Disease Without Cognitive Degradation|Brain Trauma|Acute Hydrocephaly
Interventions: BIOLOGICAL: administration of stable isotope-labelled leucine-|OTHER: collection of CSF, blood, urine, saliva
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension
Status: ACTIVE_NOT_RECRUITING
Conditions: Gaucher Disease Type 1|Gaucher Disease Type 3
Interventions: DRUG: venglustat (GZ402671)|DRUG: imiglucerase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: National Surgical Adjuvant Study of Breast Cancer(N-SAS BC) 07 [RESPECT]
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab monotherapy|DRUG: trastuzumab and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Therapy on Dyspnea Severity and Vital Signs
Status: RECRUITING
Conditions: Dyspnea|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Music Therapy|OTHER: No Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Abiraterone With Discontinuation of Gonadotropin-Releasing Hormone Analogues in Metastatic Prostate Cancer
Status: UNKNOWN
Conditions: Prostatic Neoplasms
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of IONIS-FB-LRx, an Antisense Inhibitor of Complement Factor B, in Adult Participants With Primary IgA Nephropathy
Status: COMPLETED
Conditions: Primary IgA Nephropathy
Interventions: DRUG: IONIS-FB-LRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Effectiveness of Spinal Sealant
Status: COMPLETED
Conditions: Spinal Procedure Requiring Dura Incision
Interventions: DEVICE: Spinal Sealant System|DEVICE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT