pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Diabetic Foot Ulcer Registry
Status: RECRUITING
Conditions: Diabetic Foot Ulcer Outcome|Quality of Patient Care
Interventions: BIOLOGICAL: cellular and tissue based therapy|DEVICE: negative pressure wound therapy|PROCEDURE: debridement|PROCEDURE: advanced wound therapy|DIETARY_SUPPLEMENT: Nutritional screening|DEVICE: off-loading|DEVICE: Hyperbaric oxygen Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Program Development Study for Emotional Intelligence
Status: COMPLETED
Conditions: Emotional Intelligence|Nursing|Education|Nurse's Role
Interventions: BEHAVIORAL: Emotional Intelligence Development Program|BEHAVIORAL: Plasebo Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Botox Before Modified Lip Repositioning Repositioning Only in Relapse of the Excessive Gingival Display Within One Year
Status: NOT_YET_RECRUITING
Conditions: Excessive Gingival Display
Interventions: PROCEDURE: botox prior to modified lip repostioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of an Intelligent Balance Training System Providing Weight-bearing Feedback in Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Balance function, gait ability, weight- distribution and weight-shifting|BEHAVIORAL: Weight- distribution and weight-shifting training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation
Status: RECRUITING
Conditions: Sepsis|Disseminated Intravascular Coagulation
Interventions: DRUG: Heparin Sodium|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care Planning for Prostate Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer Survivor|Prostate Adenocarcinoma
Interventions: OTHER: Questionnaire Administration|OTHER: Survivorship Care Plan (SCP)|OTHER: Treatment Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities
Status: COMPLETED
Conditions: Dry Eye Disease|Dry Eye|Kerato Conjunctivitis Sicca
Interventions: DEVICE: Cross-linked hyaluronic acid eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) -Post-Traumatic Epilepsy (PTE)
Status: RECRUITING
Conditions: Epilepsy, Traumatic|Brain Injuries, Traumatic
Interventions: BEHAVIORAL: Home Based Self-management and Cognitive Training Changes lives in post traumatic epilepsy (HOBSCOTCH-PTE)|BEHAVIORAL: HOBSCOTCH-PTE for Caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: DRUG: ZD6474 (Vandetanib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Amoxicillin Versus Placebo for (Fast Breathing) Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Tachypnea
Interventions: DRUG: Placebo|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)
Status: COMPLETED
Conditions: Multiple System Atrophy - Parkinsonian Subtype (MSA-P)|Multiple System Atrophy - Cerebellar Subtype (MSA-C)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EndoBarrier TM Gastrointestinal Liner Diabetes Trial
Status: UNKNOWN
Conditions: Overweight and Obesity|Diabetes
Interventions: DEVICE: EndoBarrier TM Gastrointestinal Liner|OTHER: Best Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Relapse & Recurrence of Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium / Fluoxetine|DRUG: Lithium / Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Reactogenicity and Immunogenicity of Fractional-dose Inactivated Polio Vaccine (fIPV) Given Intradermally With Double Mutant Enterotoxigenic Escherichia Coli Heat Labile Toxin (dmLT) Adjuvant
Status: COMPLETED
Conditions: Polio
Interventions: BIOLOGICAL: dmLT|BIOLOGICAL: fIPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HAI Via Interventionally Implanted Port Catheter Systems
Status: UNKNOWN
Conditions: Colorectal Cancer|Liver Neoplasms|Hepatocellular Carcinoma|Gallbladder Cancer|Bile Duct Cancer
Interventions: DEVICE: interventionally implanted hepatic arterial port catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Lisinopril|DRUG: Amlodipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: HSD-016|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation for Major Depression With and Without Mindfulness
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Behavioral Activation without Mindfulness|BEHAVIORAL: Behavioral Activation with Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oncological Surgery in Times of COVID-19: Effectiveness of Preoperative Screening for Sars-Cov-2
Status: UNKNOWN
Conditions: SARS-CoV-2|Oncology|Surgery
Interventions: DIAGNOSTIC_TEST: PT-PCR test for SARS-CoV-2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alzheimer's PET Imaging in Racially/Ethnically Diverse Adults
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: 18F-MK-6240|DRUG: 18F-Florbetaben
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-intensity Shockwave Therapy for Non-bacterial Prostatitis/Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Prostatitis
Interventions: DEVICE: Dornier Aries 2 device|DEVICE: Dornier Aries 2 device|DEVICE: Dornier Aries 2 device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Drainage of Subglottic Secretions on Pneumonia Acquired Under Mechanical Ventilation
Status: COMPLETED
Conditions: ICU's Patients Under Mechanical Ventilation
Interventions: PROCEDURE: drainage of subglottic secretions (HiLo Evac tube)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: doxycycline|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information on the Safety and How Radium-223 Dichloride, an Alpha Particle-emitting Radioactive Agent, Works Under Routine Clinical Practice in Taiwan in Patients With Castration-resistant Prostate Cancer (CRPC) Which Has Spread to the Bone
Status: COMPLETED
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: interACTION: A Portable Joint Function Monitoring and Training System for Remote Rehabilitation Following TKA
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: InterACTION|OTHER: Standard of Care Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|PreDiabetes|Obesity
Interventions: PROCEDURE: Metabolic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3D Printed Modified Twin Block for Correction of Skeletal Class II Malocclusion in Growing Females
Status: UNKNOWN
Conditions: Class II Malocclusion, Division 1
Interventions: DEVICE: 3D printed Modified Twin Block Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Which Ventilatory Strategy is Better for Lung in Upper Abdominal Surgeries?
Status: UNKNOWN
Conditions: Anesthesia Induced Atelectasis
Interventions: PROCEDURE: Low PEEP|PROCEDURE: High PEEP|PROCEDURE: High PEEP/RM|DEVICE: Lung ultrasonogrphy assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Sparing Anesthesia in Cervical Spine Surgery
Status: RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Pain, Chronic|Pain, Nociceptive|Ketamine|Lidocaine|Analgesia|Analgesics|Cervical Spine Surgery
Interventions: DRUG: ketamine-lidocaine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Safety Study of Dendritic Cell Vaccine to Treat Patients With Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: COMBIG-DC (ilixadencel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Health Intervention to Achieve Appropriate Gestational Weight Gain in Overweight/Obese Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Weight Gain
Interventions: BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter, Prospective, Non-randomized, Single-arm, Interventional Study for the Evaluation of the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Anterior Vaginal Wall Prolapse With/Without Apical/Uterine Descent
Interventions: DEVICE: SRS - Self Retaining Support system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Surgical Benefit and Pt.Tolerability Between Two Different Bowel Cleansing Regimens Performed Prior to Pelvic Reconstructive Surgery. Does One Bowel Cleansing Regimen Improve the Surgeons Visual Field Significantly Better Than the Other.
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: Mechanical Bowel Prep|OTHER: No Mechanical Bowel Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose:
Clinical trial: A Study of BBI608 Administered in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Cancers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: BBI608|DRUG: Ipilimumab|DRUG: Nivolumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy
Status: COMPLETED
Conditions: Pre-Eclampsia|Cathepsin B Level|Pentraxin 3 Level
Interventions: OTHER: Cathepsin B and pentraxin 3 levels in preeclampsia with pregnant women
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: IIV Flu Vaccine|DRUG: Metronidazole|DRUG: Neomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS
Status: RECRUITING
Conditions: Patients With Aterosclerotic Carotid Stenosis|Symptomatic Patients (Stenosis > 50%)|Asymptomatic Patients (Stenosis ≥80%)
Interventions: DEVICE: Emboshield NAV6™|DEVICE: Mo.Ma™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate the Safety and Efficacy of AK101 Injection Subcutaneously in Subjects With Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: AK101 injection SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COV-COMPARE Immunogenicity of Vaccine VLA2001 Compared to AZD1222
Status: COMPLETED
Conditions: SARS-CoV-2 Virus Infection
Interventions: BIOLOGICAL: VLA2001|BIOLOGICAL: AZD1222|BIOLOGICAL: VLA2001 - adolescent part|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Comparing Propofol to Midazolam Plus Meperidine Sedation for Outpatient Colonoscopy
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: propofol (sedation for outpatient colonoscopy)|DRUG: midazolam plus meperidine (sedation for outpatient colonoscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Olive Polyphenols in Cardiovascular Prevention
Status: RECRUITING
Conditions: Hypertension, Systolic
Interventions: DIETARY_SUPPLEMENT: Tensiofytol®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early and Adequate Protein Feeding Post-Traumatic Injury
Status: COMPLETED
Conditions: Protein Feeding in Post-traumatic Injury Patients
Interventions: DRUG: Routine Nutritional Support plus supplemental IV amino acids|OTHER: Routine Nutritional Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Fondaparinux Sodium When Used With Intermittent Pneumatic Compression to Prevent Venous Thromboembolic (IPC) Versus IPC Alone for the Prevention of Venous Thromboembolic Events in Subjects at Increased Risk Undergoing Major Abdominal Surgery (APOLLO).
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: fondaparinux sodium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DIAGNOSTIC_TEST: Cellular immunity vs SARS-CoV-2|DIAGNOSTIC_TEST: Humoral immunity vs SARS-CoV-2|DIAGNOSTIC_TEST: Cellular immunity vs Varicella Zoster Virus|DIAGNOSTIC_TEST: Humoral immunity vs Varicella Zoster Virus|DIAGNOSTIC_TEST: Diphtheria toxin-binding IgG|DIAGNOSTIC_TEST: Tetanus toxoid-binding IgG|DIAGNOSTIC_TEST: T-cell populations and markers characterization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectivness of Tramadol or Topic Lidocaine on Postoperative Analgesia in Laparoscopic Colorectal Resection.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Comparison of analgesic efficacy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Posterior Nasal Neurectomy With Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis:A Comparative Study
Status: UNKNOWN
Conditions: Nasal Polyps
Interventions: PROCEDURE: Posterior neurectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Deep Vein Arterialization Post-Market Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: Percutaneous deep vein arterialization|DEVICE: LimFlow System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MagnaSafe Registry: Determining the Risks of Magnetic Resonance Imaging (MRI) in the Presence of Pacemakers and Implantable Cardioverter Defibrillators (ICDs)
Status: COMPLETED
Conditions: Need for MRI Imaging With Pacemaker or|Implantable Cardioverter Defibrillator Implanted
Interventions: DEVICE: MRI with pacemaker or ICD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Dose Dental Pain Study Of Ibuprofen Extended Release
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen 600 mg ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vessel Wall Response of the Zotarolimus Drug-eluting Stent Implanted in AMI Assessed by Optical Coherence Tomography
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: ENDEAVOR® drug-eluting stent (Medtronic, Santa Rosa, CA)|DEVICE: DRIVER bare metal stent (Medtronic, Santa Rosa, Ca)|DEVICE: Coronary stent implantation|DEVICE: Bare Metal Coronary Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation to Enhance Peripheral Nerve Regeneration
Status: RECRUITING
Conditions: Peripheral Nerve Injuries
Interventions: PROCEDURE: Post surgical electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soluble Hyaluronic Acid Microneedle VS. Non-ablative Fractional Laser on Infraorbital Wrinkles.
Status: UNKNOWN
Conditions: Wrinkle
Interventions: PROCEDURE: Soluble Hyaluronic Acid Microneedle|PROCEDURE: Non-fractional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Air Travel Safety in Neuromuscular Dystrophy: Standard Versus Prolonged High Altitude Simulation Tests
Status: COMPLETED
Conditions: Neuromuscular Diseases|High Altitude Hypoxia
Interventions: DRUG: 15% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Filgotinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block
Status: WITHDRAWN
Conditions: Hip Fractures|Analgesia|Opioid Use|Pain, Postoperative
Interventions: PROCEDURE: Cephalomedullary nailing of extracapsular hip fracture|DEVICE: cephalomedullary nail|DRUG: Regional Anesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Micro-doses Erytropoietin on Exercise Capacity in Male and Females
Status: ACTIVE_NOT_RECRUITING
Conditions: Sports Drug Abuse
Interventions: DRUG: EPO|OTHER: Control group - saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Pomadomide in Combination With Rituximab and Methotrexate for Newly-diagnosed Primary Central Nervous System Lymphoma
Status: RECRUITING
Conditions: PCNSL
Interventions: DRUG: Pomalidomide|DRUG: Rituximab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-operative Knee Range of Motion and Functions Between Intraoperative Complete and Incomplete Patellofemoral Articular Contacts in Patients Undergoing Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Complete Contact|Incomplete Contact
Interventions: PROCEDURE: Complete patellofemoral articular contact|PROCEDURE: Incomplete patellofemoral articular contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reactive Balance Training and Fitness
Status: ACTIVE_NOT_RECRUITING
Conditions: CVA (Cerebrovascular Accident)
Interventions: OTHER: Reactive balance training|OTHER: Aerobic and strength training (AST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Effect of GSK256073, an HM74A Receptor Agonist, on Glucose and NEFA Levels in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK256073|DRUG: GSK256073|DRUG: GSK256073|DRUG: GSK256073|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ayurvedic Nutritional Counseling for Patients With IBS in Comparison to Conventional Nutritional Counseling
Status: COMPLETED
Conditions: IBS - Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Ayurvedic nutritional counseling|BEHAVIORAL: Conventional nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Mipomersen on Cardiac Repolarization Conducted in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: mipomersen sodium|DRUG: mipomersen sodium|DRUG: moxifloxacin hydrochloride (Avelox®)|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy of Spine With Postural Correction Exercise Compared With Conventional Therapy in Patients With Adhesive Capsulitis - A Randomised Clinical Trial
Status: RECRUITING
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Spinal Manual therapy used in Physiotherapy Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients
Status: RECRUITING
Conditions: Cardiovascular Diseases|Oxidative Stress|Endothelial Dysfunction
Interventions: DRUG: Nitrogen Gas for Inhalation|OTHER: Blood withdrawal|DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Crestor®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction in Single Implant Mandibular Complete Overdentures Retained by CM LOC Versus Ball Attachment
Status: UNKNOWN
Conditions: Edentulous|Dental Implant
Interventions: DEVICE: CM LOC|DEVICE: ball attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bond Failure of Two Types of Molar Buccal Tubes
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: 3M Unitek Victory Series™ Superior Fit Buccal Tube with APC™ Flash-Free Adhesive. 4069-6103 / 4069-6114 / 4069-6203 / 4069-6214|DEVICE: 3M Unitek Victory Series™ Superior Fit Buccal Tube with APC™ II Adhesive. 3069-6103 / 3069-6114 / 3069-6203 / 3069-6214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Botulinum Toxin A in Adult Subjects With Raynaud Phenomenon Secondary to Systemic Sclerosis
Status: COMPLETED
Conditions: Raynaud Phenomenon Secondary to Systemic Sclerosis
Interventions: DRUG: BOTOX® solution|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Fitness, Lung Function, Muscular Oxygen Saturation, and Quality of Life in T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: exercise testing with near-infrared spectroscopy|BEHAVIORAL: lung function testing|BEHAVIORAL: quality of life
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fasting-mimicking Diet and Periodontitis (FMD)
Status: RECRUITING
Conditions: Periodontal Disease, AVDC Stage 3|Periodontal Disease, AVDC Stage 4|Periodontitis
Interventions: PROCEDURE: Fasting-mimicking diet + non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intranasal Insulin on POCD and POD
Status: NOT_YET_RECRUITING
Conditions: Delirium|Heart Diseases
Interventions: DRUG: Regular Insulin, Human 100 UNT/ML|DRUG: Normal Saline Flush, 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VAH Versus VA for Salvage Therapy of R/R-AML
Status: UNKNOWN
Conditions: Venetoclax Combined With Azacitidine Plus Homoharringtonine|Venetoclax Combined With Azacitidine
Interventions: DRUG: VEN combined with azacitidine plus homoharringtonine|DRUG: VEN combined with azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Lymphocytes for the Treatment of AdV, CMV, EBV, BKV and Aspergillus Fumigatus Infections After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Opportunistic Fungal Infection|Opportunistic Viral Infection|Bone Marrow Transplant Infection
Interventions: BIOLOGICAL: Pentavalent-specific T cells (penta-STs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Insulin and Its Effect on Postprandial Metabolism in Comparison to Subcutaneous Insulin
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: aspart|DRUG: Nasulin™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Carpometacarpal Osteoarthritis|Rhizarthrosis|Thumb Osteoarthritis
Interventions: PROCEDURE: Trapeziectomy with suspensionplasty|PROCEDURE: Joint alloplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS)
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome|Pain
Interventions: DRUG: Oxycodone naloxone prolonged release tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy for Chronic Pain in Integrated Primary Care
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Focused Acceptance & Commitment Therapy (FACT)|BEHAVIORAL: Enhanced Treatment as Usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Oxytocin Infusion Versus Pulsatile Intravenous Oxytocin for Augmentation of First Stage of Labor
Status: UNKNOWN
Conditions: Failed Induction (of Labor) by Oxytocin
Interventions: DRUG: Pulsatile Oxytocin|DRUG: Continuous Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study on A Following-up System of Native Arteriovenous Fistulae
Status: COMPLETED
Conditions: Arteriovenous Fistulae
Interventions: PROCEDURE: Assessment guiding surgery and puncture for AVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Guided Biofeedback on Hemodialysis and the Reduction of IntraDialytic Hypotension
Status: COMPLETED
Conditions: Hypotension
Interventions: OTHER: BioLogic RR|OTHER: Hemodialysis without biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of PPE on Children's Fear in Dental Office
Status: COMPLETED
Conditions: COVID-19|Infections|COVID-19 Virus Infection
Interventions: DEVICE: reusable respirators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: SMAD4 Methylation and Expression Levels in Non-melanocytic Skin Cancers; SMAD4 Protein Positivity
Status: UNKNOWN
Conditions: Basal Cell Carcinoma
Interventions: OTHER: SMAD4 expression and methylation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: UCN-01, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 7-hydroxystaurosporine|DRUG: fluorouracil|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Tailored Messages on the Usage of Emollient in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: BEHAVIORAL: Tailored leaflet group|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II
Status: UNKNOWN
Conditions: Hepatitis, Autoimmune|Primary Biliary Cholangitis
Interventions: DRUG: Ursodeoxycholic acid|DRUG: Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19
Status: COMPLETED
Conditions: Critical Confirmed Coronavirus Disease (COVID)-19
Interventions: DRUG: Sirukumab|DRUG: Placebo|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
Status: RECRUITING
Conditions: Dental Caries in Children|Vital Pulp Therapy
Interventions: DRUG: Mineral trioxide aggregate (dressing material)|DRUG: Melatonin (dressing material)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users
Status: RECRUITING
Conditions: Meibomian Gland Dysfunction|Dry Eye
Interventions: PROCEDURE: Systane iLux thermal pulsation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Evaluate the Relative Oral Bioavailability and Food Effect After Single Dose Administration of JNJ-54861911 Tablet in Healthy Elderly Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54861911 (Treatment A)|DRUG: JNJ-54861911 (Treatment B)|DRUG: JNJ-54861911 (Treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Status: COMPLETED
Conditions: Rhytides|Wrinkle
Interventions: DEVICE: Venus Viva
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic Heart Innervation in Patients With Tako-Tsubo Cardiomyopathy
Status: COMPLETED
Conditions: Apical Ballooning Syndrome|Nervous System Diseases, Sympathetic
Interventions: DRUG: Placebo|DRUG: alpha-lipoic acid|DRUG: L-acetyl carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thymoquinone Extracted From Nigella Sativa in the Treatment of Arsenical Keratosis
Status: UNKNOWN
Conditions: Keratotic Nodular Size
Interventions: DRUG: Nigella sativa seeds extract containing ointment intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma
Status: WITHDRAWN
Conditions: Advanced Urothelial Carcinoma
Interventions: DRUG: Magrolimab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
Status: COMPLETED
Conditions: Quality of Life|Injection Site Reaction|Adverse Drug Event|Systemic Reaction
Interventions: BIOLOGICAL: mRNA COVID-19|BIOLOGICAL: IIV4|OTHER: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Closed-loop DBS in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Closed-loop DBS stimulation for 24 hours|OTHER: Open-loop DBS stimulation for 24 hours|OTHER: Closed-loop DBS stimulation for 72 hours|OTHER: Open-loop DBS stimulation for 72 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Assessment of a Bedside-testing System (Nephrocheck™) for Acute Kidney Injury After Thoracoabdominal Aortic Surgery
Status: COMPLETED
Conditions: Early Assessment of AKI After TAAA Repair
Interventions: OTHER: Nephrocheck bed side testing of AKI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Tolerability of Topical Therapies for the Condition of Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Plaque-Type Psoriasis
Interventions: DRUG: Olux-E Foam|DRUG: Clobex lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial in Patients With Psoriasis Treated With Methotrexate Using an Optimized Treatment Schedule (METOP)
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Methotrexate|DRUG: Placebo ( for Methotrexate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: How Different Beta-2 Receptor Genotypes Affect an Asthmatic's Response to Regular Salmeterol Treatment
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|De Novo|Age More 60yr
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|DRUG: Quizartinib|DRUG: Cytarabine|DRUG: Venetoclax|DRUG: Quizartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome
Status: COMPLETED
Conditions: Genetic Disorder|Noonan Syndrome
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ranolazine Loading to Prevent PCI-induced Myocardial Injury
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Effects of 7 Days of Gonadotropin Releasing Hormone (GnRH) Treatment in Men With Hypogonadism
Status: COMPLETED
Conditions: Kallmann Syndrome|Idiopathic Hypogonadotropic Hypogonadism|GnRH Deficiency
Interventions: DRUG: gonadotropin releasing hormone (GnRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: HYMOVIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AdditioN of Fixed Dose Combination (FDC) Of Budesonide/Formoterol Via Elpenhaler® Device in Greek Patients With asThma accΟrding to Standard Clinical Practice.
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Maintenace and As needed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone With or Without Gemcitabine in Treating Patients With Previously Untreated Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Small Intestine Cancer
Interventions: DRUG: CHOP regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamic Multiomics Evaluation of Anti-HER2 and Immunotherapy in HER2 Positive Gastric Cancer
Status: RECRUITING
Conditions: HER2 Positive Advanced Gastric Cancer
Interventions: PROCEDURE: Samples including blood and tissue collection|PROCEDURE: CTC detection|PROCEDURE: ctDNA detection|PROCEDURE: 10×genomics single cell RNA sequence|PROCEDURE: Whole exon sequence|PROCEDURE: Proteomics detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Right Ventricular Dysfunction
Interventions: PROCEDURE: Positive end-expiratory pressure titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: ACE-031 0.5 mg/kg q4wk|BIOLOGICAL: ACE-031 1.0 mg/kg q2wk|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastro-Esophageal Junction Adenocarcinoma|Gastric Cancer
Interventions: DRUG: Nab-paclitaxel 150 mg/m^2|DRUG: Oxaliplatin 85 mg/m^2|DRUG: 5-FU 1200 mg/m^2 x 2 D|DRUG: Leucovorin 400 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3154885 in Healthy Participants
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: LY3154885 - Capsule|DRUG: Placebo - Capsule|DRUG: Itraconazole|DRUG: LY3154885 - Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Living With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Survey on patient's perspectives on the development of an structured education programme for PCOS|OTHER: Pre-pilot questionnaire|OTHER: Piloting the structured education programme for PCOS|OTHER: Post-pilot questionnaire|OTHER: cognitive outcomes outcome evaluation form
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Ranibizumab Administered in Conjunction With Photodynamic Therapy With Verteporfin in Patients With Subfoveal Choroidal Neovascularization and Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration (ARMD)
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: Alpha-1 MP|DRUG: alpha-1 proteinase inhibitor (human)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT