pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure
Status: COMPLETED
Conditions: Fetal Alcohol Spectrum Disorders|Fetal Alcohol Syndrome|Partial Fetal Alcohol Syndrome|Alcohol Related Neurodevelopmental Disorder|Prenatal Alcohol Exposure
Interventions: DRUG: Choline bitartrate|DIETARY_SUPPLEMENT: Placebo for choline bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dialysis Geriatric Care Model
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Kidney Diseases|Dialysis|Geriatric
Interventions: BEHAVIORAL: Geriatric Care Model|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DIStal Versus COnventional Radial Access for COMPLEX Large-bore Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Vascular Access Site Occlusion
Interventions: PROCEDURE: Complex PCI with Ultimaster family drug-eluting stent (Terumo Corp., Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: SHR8554|DRUG: SHR8554|DRUG: Saline Solution|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: eMESH Struct. 2022-23
Status: RECRUITING
Conditions: Septic Shock|Chronic Heart Failure
Interventions: DIAGNOSTIC_TEST: ultrasound cardiography|DIAGNOSTIC_TEST: FDG PET scan|DIAGNOSTIC_TEST: Palmitate PET scan|DIAGNOSTIC_TEST: Acetate PET scan|DIAGNOSTIC_TEST: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing RT With Cetuximab + Xevinapant to RT With Cetuximab-placebo in Patients With Head and Neck Cancer
Status: SUSPENDED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Xevinapant|DRUG: Placebo|DRUG: cetuximab|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The AutoloGel™ Post-Market Surveillance (TAPS) Program
Status: TERMINATED
Conditions: Wounds|Leg Ulcers|Pressure Ulcers|Diabetic Foot Ulcers
Interventions: DEVICE: AutoloGel System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Biperiden Lactate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Salt and Sugar in Campus Foods: A Malaysian Study
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: Reduction in Salt and Sugar|DEVICE: The potentiometer|DEVICE: Dry Ashing Method Followed by Flame Atomic Absorption Spectrometry (FAAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trabeculectomy With Ologen Collagen Implant vs Trabeculectomy With Provisc in Steroid Induced Glaucoma
Status: COMPLETED
Conditions: Steroid Induced Glaucoma
Interventions: DEVICE: Ologen Collagen Matrix|DRUG: Provisc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artery Embolization vs Operation of Benign Prostate Hyperplasia
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia|Post-Op Complication|Embolization Therapeutic|Transurethral Resection of Prostate Syndrome
Interventions: PROCEDURE: Prostate operation or prostate artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cardiovascular Prevention Program
Status: RECRUITING
Conditions: Cardiovascular Prevention
Interventions: OTHER: International Physical Activity Questionnaire|OTHER: Six minute walking test|OTHER: SF-36, Euro-Qol 5D-5L, Perceived stress scale-10, Pittsburgh Sleep Quality Index, Depression Anxiety Stress scale- 21.|OTHER: MEDAS|OTHER: Intima-media thickness (IMT)|BIOLOGICAL: Blood sampling|BIOLOGICAL: Stool Sample Culture Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Escalation Trial Of PF-04603629 Given To Subjects With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: PF-04603629|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity
Status: WITHDRAWN
Conditions: Large B-cell Lymphoma|Diffuse Large B Cell Lymphoma|Primary Mediastinal Large B Cell Lymphoma|High-grade B-cell Lymphoma|Follicular Lymphoma
Interventions: OTHER: Telemedicine visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Mild Cognitive Impairment|Subjective Cognitive Decline
Interventions: PROCEDURE: Preventive strategies advice and dementia risk estimate disclosure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Multisite Sampling to Detect C. Trachomatis or N. Gonorrheae Compared With Vaginal Sampling in Women at Risk for Sexually Transmitted Infections
Status: RECRUITING
Conditions: Sexually Transmitted Infection
Interventions: DIAGNOSTIC_TEST: Vaginal, Oral and anal sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A 56-day Clinical Study on Facial Skin Rejuvenation
Status: COMPLETED
Conditions: Skin Manifestations|Wrinkle|Photoaging
Interventions: COMBINATION_PRODUCT: Fractional picosecond laser treatment followed by daily use of formulations containing MLYAAT-1002®.|COMBINATION_PRODUCT: Fractional picosecond laser treatment followed by daily use of formulations without MLYAAT-1002®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Gel During Transrectal Sonography
Status: COMPLETED
Conditions: Gynecologic Diseases
Interventions: DRUG: Lidocaine gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise Intensity on Brain & Mental Health in Stress
Status: NOT_YET_RECRUITING
Conditions: Healthy Adults|Adults With Stress-related Symptoms
Interventions: BEHAVIORAL: Seated rest|BEHAVIORAL: Exercise at moderate intensity|BEHAVIORAL: Exercise at vigorous intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of 10 Milligram (mg) and 5 mg Tablets Versus Conventional Tablets of Dolutegravir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Conventional dolutegravir 10 mg tablet|DRUG: Conventional dolutegravir 50 mg tablet|DRUG: Dispersible dolutegravir 5 mg tablet|DRUG: Conventional dolutegravir 25 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Rituximab in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: methotrexate|DRUG: rituximab|DRUG: corticosteroids|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: monosialotetrahexosylganglioside Sodium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating Overcoming Anxiety in Pregnancy and Postpartum as an Online Self-Directed Program
Status: COMPLETED
Conditions: Perinatal Anxiety|Perinatal Depression
Interventions: BEHAVIORAL: Overcoming Anxiety in Pregnancy and Postpartum Online Self-Directed Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Limiting IV Chloride to Reduce AKI After Cardiac Surgery
Status: COMPLETED
Conditions: Patients Undergoing Cardiothoracic Surgery
Interventions: OTHER: Low-chloride perioperative intravenous fluid strategy|OTHER: High-chloride perioperative intravenous fluid strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Matricariae Chamomilla L., Melissa Officinalis L. and Tyndallized Lactobacillus Acidophilus (H122) for Infantile Colics
Status: COMPLETED
Conditions: Infantile Colics
Interventions: DIETARY_SUPPLEMENT: Standardized extract of Chamomilla L., Melissa Officinalis L. and tyndallized L. Acidophilus (H122)|DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938 (108 CFU)|DRUG: Simethicone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction|Reperfusion Injury, Myocardial
Interventions: OTHER: Treg levels and CMR results
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Gastric Adenocarcinoma|HER2 Gene Mutation
Interventions: DRUG: Pembrolizumab|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of the QLT Proprietary Olopatadine-PPDS in Subjects With Seasonal Allergic Conjunctivitis to Ragweed in an Environmental Exposure Chamber Model.
Status: TERMINATED
Conditions: Seasonal Allergic Conjunctivitis to Ragweed
Interventions: DRUG: Olopatadine|DRUG: Olopatadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of e-CBT to Mental Health Coaching for GAD
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: e-CBT|BEHAVIORAL: Mental Health Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Upfront Surgery Versus Neoadjuvant Chemotherapy in Patients With Advanced Ovarian Cancer (SUNNY)
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: PROCEDURE: Upfront cytoreductive surgery|PROCEDURE: Interval debulking surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Using Docetaxel Cytoxan in Breast Cancers With High Recurrence Scores
Status: TERMINATED
Conditions: Breast Neoplasms|Breast Cancer|Cancer of the Breast
Interventions: DRUG: Docetaxel with Cytoxan|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals
Status: RECRUITING
Conditions: Histamine|Cowhage
Interventions: OTHER: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Radiation Dosimetry, Biokinetics, and Effectiveness of [18F]MK3328 (MK-3328-001)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: [18F]MK-3328
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Apatinib Combined With S-1 for Patients With Advance Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib Mesylate tablets combined with S-1 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Synvisc® in Chinese Subjects With Symptomatic Osteoarthritis of the Knee(s)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Hylan G-F 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab as Treatment for Recurrent/Metastatic Nasopharyngeal Carcinoma After Failing 2 Lines or More Previous Chemotherapy
Status: WITHDRAWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Randomized Placebo-controlled Study of Safety and Immunogenicity of GamEvac-Lyo
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: GamEvac-Lyo (component A)|OTHER: Placebo|BIOLOGICAL: GamEvac-Lyo (component B)|BIOLOGICAL: GamEvac-Lyo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Topiramate Bioequivalence Study Brazil - Fast
Status: COMPLETED
Conditions: Epilepsy, Tonic-Clonic
Interventions: DRUG: Topiramate coated tablet|DRUG: Topamax® coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I Study of Colistin Methanesulfonate Sodium
Status: COMPLETED
Conditions: Infections, Pseudomonas
Interventions: DRUG: Colistimethate sodium|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doripenem in the Treatment of Complicated Intra-Abdominal Infections
Status: COMPLETED
Conditions: Bacterial Infections and Mycoses|Appendicitis|Cholecystitis|Pancreatitis|Peritonitis
Interventions: DRUG: Doripenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Robotic Hand Therapy for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Hand Functions|Rehabilitation|Robotic Rehabilitation
Interventions: OTHER: Robotic rehabilitation|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous Iron Isomaltoside 1000 (Monofer®) as Mono Therapy (Without Erythropoiesis Stimulating Agents) in Comparison With Oral Iron Sulfate in Subjects With Non-myeloid Malignancies Associated With Chemotherapy Induced Anaemia (CIA)
Status: COMPLETED
Conditions: Non-myeloid Malignancies|Chemotherapy Induced Anaemia
Interventions: DRUG: iron isomaltoside 1000|DRUG: iron sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: DRUG: alteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Danish Out-of-Hospital Cardiac Arrest Study
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Post-Cardiac Arrest Syndrome
Interventions: DRUG: Dexamethasone|PROCEDURE: Backrest elevation|PROCEDURE: Early wakeup call|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Natural fruit extract|OTHER: Placebo|OTHER: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Local Analgesia in Knee- and Hipatroplastic Surgery in Patients With Rheumatic Disease: Extra- vs. Intracapsulare Position of Catheter
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Orthopedic Surgery|Analgesia
Interventions: PROCEDURE: Position of catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Homocysteine After Laparoscopic Roux-enY Gastric Bypass
Status: COMPLETED
Conditions: Obesity, Morbid|Homocystine; Metabolic Disorder|Bariatric Surgery Candidate|Folate Deficiency|Vitamin B 12 Deficiency
Interventions: PROCEDURE: laparoscopic long limb roux-en-Y gastric bypass
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort
Status: RECRUITING
Conditions: Atopic Dermatitis|Skin Diseases|Eczema
Interventions: DEVICE: Narrowband UVB phototherapy|DEVICE: Broadband UVB phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Reduction of Cardiac Problems in Multiple Sclerosis Patients With Mitoxantrone and Dexrazoxane in Combination
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: Dexrazoxane (DRZ) plus Mitoxantrone (MX)|DRUG: Placebo plus Mitoxantrone (MX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasma Rich Growth Factors in Venous Ulcers
Status: UNKNOWN
Conditions: Venous Ulcers
Interventions: PROCEDURE: PRGF+ Cleaning, debridement of the wound, application of the corresponding dressing and using of antibiotics if necessary|PROCEDURE: Cleaning, debridement of the wound, application of the corresponding dressing and using of antibiotics if necessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Etanercept for the Treatment of Active, Severe, and Advanced Axial Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Etanercept (Enbrel)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of rTMS and tDCS as Adjunctive Rehabilitation for Cerebrovascular Disease-related Gait Dysfunction
Status: UNKNOWN
Conditions: Repetitive Transcranial Magnetic Stimulation|Transcranial Direct Current Stimulation|Cerebrovascular Disease|Gait Dysfunction, Neurologic
Interventions: DEVICE: Active rTMS|DEVICE: Sham rTMS|DEVICE: Active tDCS|DEVICE: Sham tDCS|OTHER: Walking training|OTHER: Cognition training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Study to Evaluate Safety and Effectiveness of the Low Glucose Suspend Feature
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Medtronic MMT-754 Veo Insulin pump testing Low Glucose Suspend (LGS) feature|DEVICE: Medtronic (NO LGS FEATURE ) using Paradigm® Revel™2.0 Pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Injection, 161Tb-SibuDAB,1GBq|DRUG: Injection, 177Lu-PSMA-I&T, 1GBq|DRUG: Injection, 161Tb-SibuDAB, Dose Escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Epacadostat + Pembrolizumab in Head and Neck Cancer Patients, Who Failed Prior PD-1/PD-L1 Therapy
Status: WITHDRAWN
Conditions: Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|DRUG: epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Pantoprazole
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms of Alcohol Sensitivity in AERD
Status: UNKNOWN
Conditions: Aspirin-Sensitive Asthma With Nasal Polyps|Samter's Syndrome
Interventions: DIETARY_SUPPLEMENT: Water|DIETARY_SUPPLEMENT: Red wine|DIETARY_SUPPLEMENT: Polyphenolic Compounds
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determination of the Optimal Treatment Target in Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Treatment Algorithm A|BIOLOGICAL: Treatment Algorithm B|BIOLOGICAL: Treatment Algorithm C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CRP and S&A for Inpatient Veterans
Status: RECRUITING
Conditions: Alcoholism|Substance-related Disorders|Dual Diagnosis
Interventions: BEHAVIORAL: Combined Recovery Program|BEHAVIORAL: Stable & Able (S&A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Pregnancy and Post-partum Feeding Method (Breastfeeding Versus Bottlefeeding) on Maternal Hemodynamics (Central and Peripheral) and Vascular Function
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Breastfeeding|BEHAVIORAL: Bottlefeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of Vedolizumab in the Treatment of Chronic Pouchitis
Status: COMPLETED
Conditions: Pouchitis
Interventions: DRUG: Vedolizumab Placebo|DRUG: Ciprofloxacin|DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men
Status: COMPLETED
Conditions: Male Infertility
Interventions: COMBINATION_PRODUCT: proxeed plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Two Blades of Videolaryngoscope in Simulated Difficult Airway in Children
Status: COMPLETED
Conditions: Intubation;Difficult
Interventions: DEVICE: D-blade of videolaryngoscope|OTHER: simulated difficult airway|DEVICE: Macintosh videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ultherapy™ Treatment Following Sculptra® Treatment
Status: COMPLETED
Conditions: Skin Laxity
Interventions: DEVICE: Ulthera® System|DRUG: Sculptra®|OTHER: Sculptra® treatment followed by Ultherapy™ treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: Metformin|DRUG: Melatonin|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors
Status: COMPLETED
Conditions: Kidney Transplantation|Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Urine Biomarkers|DIAGNOSTIC_TEST: Gene expression profiling of donor kidneys by microarray|DIAGNOSTIC_TEST: Gene expression profiling of recipient kidneys by microarray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Rapid ART Initiation on Retention in Care in the Southern US
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: BEHAVIORAL: Rapid start of antiretrovirals|BEHAVIORAL: Retrospective analysis|BEHAVIORAL: Non- RAPID start
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Fosinopril|OTHER: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Setria Performance Blend Supplementation
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Setria performance blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Omadacycline vs Moxifloxacin for the Treatment of CABP (EudraCT #2013-004071-13)
Status: COMPLETED
Conditions: Bacterial Pneumonia|Community-Acquired Infections
Interventions: DRUG: Omadacycline|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Tablet Formulation and Dosing Regimen of Balsalazide Disodium in Mildly to Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: 5 ASA, enemas, suppositories, corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carbon-11 Acetate and Fludeoxyglucose F 18 PET Scan of the Bone in Patients With Metastatic Prostate Cancer That Has Spread to the Bone
Status: COMPLETED
Conditions: Metastatic Cancer|Prostate Cancer
Interventions: DRUG: antiandrogen therapy|DRUG: docetaxel|DIAGNOSTIC_TEST: C-11 acetate PET scan|DIAGNOSTIC_TEST: F-18 FDG PET scan|DIAGNOSTIC_TEST: Tc-99m bone scan|DIAGNOSTIC_TEST: CT scan of the chest, abdomen and pelvis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicentre Study About the Effect of Individual Reminiscence Therapy
Status: COMPLETED
Conditions: Cognitive Impairment|Cognitive Decline|Dementia|Neurocognitive Disorders
Interventions: OTHER: Reminiscence Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule|BIOLOGICAL: Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule|BIOLOGICAL: Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule|BIOLOGICAL: Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule|BIOLOGICAL: High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule|BIOLOGICAL: High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule|BIOLOGICAL: Placebo on a 0- and 28-day schedule|BIOLOGICAL: Placebo on a 0- and 14-day schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Osteopathy and Obstructive Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: osteopathic compression of Pterygopalatine node
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
Status: COMPLETED
Conditions: Necrotic Pulp|Periapical; Infection
Interventions: OTHER: Regenerative Endodontics Procedures (REPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Radiofrequency Versus Pulsed Dose for Shoulder Pain
Status: COMPLETED
Conditions: Unilateral Chronic Shoulder Pain|Bilateral Chronic Shoulder Pain
Interventions: PROCEDURE: Conventional Radiofrequency|PROCEDURE: Pulsed Dose Radiofrequency|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Faeces in Ulcerative Colitis; Restoring Nature's Homeostasis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: treatment with faecal transplantation (donor faeces)|OTHER: treatment with faecal transplantation (own faeces)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Hunger Manipulation During Feeding Intervention
Status: COMPLETED
Conditions: Feeding Disorders|Feeding and Eating Disorders|Avoidant/Restrictive Food Intake Disorder
Interventions: BEHAVIORAL: Intensive Multidisciplinary Feeding Intervention (IMFI)-Standard of Care|BEHAVIORAL: Intensive Multidisciplinary Feeding Intervention (IMFI) standard of care + rapid tube weaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19: Immune Response in Patients With Cancer Undergoing mRNA Vaccination Against SARS-CoV-2
Status: TERMINATED
Conditions: Cancer
Interventions: BIOLOGICAL: Spikevax|BIOLOGICAL: Comirnaty|BIOLOGICAL: Spikevax bivalent Original/Omicron BA.1|BIOLOGICAL: Spikevax bivalent Original/Omicron BA.4-5|BIOLOGICAL: Comirnaty Original/Omicron BA.1|BIOLOGICAL: Comirnaty Original/Omicron BA.4-5|BIOLOGICAL: Comirnaty Omicron XBB.1.5|BIOLOGICAL: Spikevax Omicron XBB.1.5
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fluorouracil, Irinotecan, Leucovorin, and Cisplatin as First-Line Therapy in Treating Patients With Metastatic Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for the Treatment of Posttraumatic Stress Among Military Personnel
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: PROCEDURE: Acupuncture, using Chinese Medicine methodology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD)
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Rocatinlimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vertical Height in Anterior Maxillary Sandwich Osteotomy: Simultaneous Versus Delayed Implant Placement
Status: UNKNOWN
Conditions: Alveolar Bone Resorption
Interventions: PROCEDURE: Anterior maxillary vertical segmental sandwich osteotomy with simultaneous implant placement|PROCEDURE: Anterior maxillary vertical segmental sandwich osteotomy using micro-plates fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 1 (Lipitor®)|DRUG: 1 (Ezetrol®)|DRUG: 1 (Lipitor®, Ezetrol®)|DRUG: 2 (Ezetrol®)|DRUG: 2(Lipitor®, Ezetrol®)|DRUG: 2 (Lipitor®)|DRUG: 3(Lipitor®, Ezetrol®)|DRUG: 3 (Lipitor®)|DRUG: 3 (Ezetrol®)|DRUG: 4 (Lipitor®)|DRUG: 4(Lipitor®, Ezetrol®)|DRUG: 4 (Ezetrol®)|DRUG: 5 (Ezetrol®)|DRUG: 5 (Lipitor®)|DRUG: 5 (Lipitor®, Ezetrol®)|DRUG: 6(Lipitor®, Ezetrol®)|DRUG: 6 (Ezetrol®)|DRUG: 6 (Lipitor®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Problem-solving: A Stroke Caregiver Early Intervention
Status: COMPLETED
Conditions: Psychological Adaptation
Interventions: BEHAVIORAL: Caregiver Problem-Solving Intervention|BEHAVIORAL: Wait List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: B-19 Parvovirus Vaccine Study
Status: TERMINATED
Conditions: Parvovirus B19 Infection
Interventions: BIOLOGICAL: VAI-VP705 (parvovirus B-19 vaccine)|DRUG: Placebo|BIOLOGICAL: MF-59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Conventional Laparoscopy Versus Robotic Surgery for Pain Relief in Patients With Deep Infiltrating Endometriosis
Status: UNKNOWN
Conditions: Endometriosis|Endometriosis-related Pain|Endometriosis Pelvic
Interventions: PROCEDURE: robotic-assisted laparoscopy|PROCEDURE: Conventional laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: recombinant interleukin-7
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Type 2 Diabetes After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass: A Randomised Single Centre Study
Status: COMPLETED
Conditions: Type 2 Diabetes|Morbid Obesity
Interventions: PROCEDURE: Bariatric surgery, either gastric bypass surgery or sleeve gastrectomy|PROCEDURE: Sleeve gastrecomy|PROCEDURE: Bastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of NNC 0151-0000-0000 in Subjects With Systemic Lupus Erythematosus (SLE)
Status: WITHDRAWN
Conditions: Inflammation|Systemic Lupus Erythematosus
Interventions: DRUG: NNC 0151-0000-0000|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquin (HCQ) in Pediatric Interstitial Lung Disease (ILD)
Status: SUSPENDED
Conditions: Interstitial Lung Disease|Diffuse Parenchymal Lung Disease|Children´s Interstitial Lung Disease
Interventions: DRUG: Hydroxychloroquine sulfate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DEVICE: Steroid-releasing sinus implant|OTHER: Post-op standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Change and Quality of Life in Obese Patients With Stage I/II Endometrial Cancer in Remission
Status: COMPLETED
Conditions: Endometrial Cancer|Weight Changes
Interventions: BEHAVIORAL: behavioral dietary intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: preventative dietary intervention|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Residual Curarization Incidence in China
Status: UNKNOWN
Conditions: Perioperative/Postoperative Complications|PORC (Postoperative Residual Curarization)
Interventions: DRUG: Vecuronium Bromide|DRUG: Rocuronium|DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Implementation of a Moral Case Delibration Meetings on the Prevalence of Burn-out Syndrome in the ICU
Status: COMPLETED
Conditions: Burnout, Professional|Caregiver Exhaustion
Interventions: OTHER: Monthly moral case deliberation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Digital Intervention for Post-Stroke Depression and Executive Dysfunction
Status: RECRUITING
Conditions: Executive Dysfunction|Depression|Stroke
Interventions: DEVICE: AKL-T01|BEHAVIORAL: Metacognitive Strategy Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study to Investigate the Safety and Maximum Tolerated Dose of Aldoxorubicin (INNO-206) Plus Doxorubicin HCL in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: aldoxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community Pharmacist Intervention to Enhance Adherence in Cardiovascular Drug Initiators
Status: RECRUITING
Conditions: Cardiovascular Diseases|Cardiovascular Disease Prevention
Interventions: BEHAVIORAL: community pharmacist intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Test the Efficacy of a Tailored Intensive Smoking Cessation Intervention in Persons With HIV (PWHs)
Status: COMPLETED
Conditions: Smoking|HIV Infections|AIDS
Interventions: BEHAVIORAL: Positively Smoke Free|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DPP-4 Inhibition, Incretins and Islet Function
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Vildagliptin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low-Level Laser Effects on Orthodontic Tooth Movement of Periodontally Compromised Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontal Diseases|Cancer Metastatic|Orthodontic Tooth Movement
Interventions: DEVICE: Biolase ;Low Level Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts
Status: COMPLETED
Conditions: Previously Treated Primary Immune Thrombocytopenia
Interventions: DRUG: rhTPO|DRUG: Eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIrtual Reality Glasses Use to Improve Lateropulsion and the Post-stroke Postural Vertical
Status: RECRUITING
Conditions: Stroke|Brain Diseases|Cerebrovascular Disorders|Postural; Defect|Cognition Disorder
Interventions: OTHER: Virtual Reality , immersion in a virtual titlted room
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone Capsule in Patients With Chronic Kidney Disease G2 and G3a Study on Safety and Pharmacokinetics
Status: UNKNOWN
Conditions: Renal Insufficiency
Interventions: DRUG: pirfenidone capsule|DRUG: pirfenidone capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.
Status: RECRUITING
Conditions: Preoperative Stress|Postoperative Cognitive Dysfunction|Postoperative Delirium
Interventions: DEVICE: Intervention with natural sounds administered via headphones|DEVICE: Intervention with natural sounds and binaural beats administered via headphones|DEVICE: Intervention with natural sounds and virtual reality administered via headphones and head mounted display|DEVICE: Intervention with natural sounds, binaural beats and virtual reality administered via headphones and head mounted display
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Metformin XR|DRUG: Placebo matching Metformin XR|DRUG: Metformin XR|DRUG: Placebo matching Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Evaluating the Efficacy of Aflibercept for the Treatment of Choroidal Neovascularization in Angioid Streaks in Young Patients (ASTRID).
Status: WITHDRAWN
Conditions: Choroidal Neovascularization in Angioid Streaks
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging
Status: SUSPENDED
Conditions: Myocardial Bridging
Interventions: DRUG: Nebivolol|DRUG: Diltiazem|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vorinostat Plus Capecitabine (X) and Cisplatin (P) for 1st Line Treatment of Metastatic or Recurrent Gastric Cancer: Zolinza+XP
Status: COMPLETED
Conditions: Gastric Cancer|Histone Deacetylase Inhibitor
Interventions: DRUG: Vorinostat, capecitabine, and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis
Status: TERMINATED
Conditions: Sinusitis|Bacterial Infections
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)|DRUG: Amoxicillin/Clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
Status: RECRUITING
Conditions: Head and Neck Cancer|Relapse|Recurrent|Refractory Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT