pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Predictors and Prognostic Factors on the Acute Ischemic Stroke
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: Drug Therapy|DIAGNOSTIC_TEST: Routine Blood Test and Image Scan|OTHER: Intravascular therapy|OTHER: Emergency Treatment|OTHER: Medical history
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair
Status: COMPLETED
Conditions: Peripheral Nerve Discontinuities
Interventions: BIOLOGICAL: Processed Nerve Allograft (human)|DEVICE: Collagen Nerve Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Mobile Cognitive Behavioral Intervention for Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder
Interventions: BEHAVIORAL: CBT2go|DEVICE: Smartphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Epacadostat|DRUG: Pembrolizumab|BIOLOGICAL: CRS-207|DRUG: Cyclophosphamide|BIOLOGICAL: GVAX Pancreas Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Effectiveness and Safety of LBBaP With Solia S and Selectra 3D Developed by BIOTRONIK
Status: RECRUITING
Conditions: Consented to Participate in the Trial and Signed an ICF|Patients With an Indication for PM Implantation or CRTP
Interventions: DEVICE: Solia S and Selectra 3D Developed by BIOTRONIK
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Unilateral vs Bilateral Laparoscopic Ovarian Drilling In Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Laparoscopic|Ovarian Drilling|Clomiphene Citrate|Polycystic Ovarian Syndrome|Unilateral|Bilateral
Interventions: OTHER: Unilateral laparoscopic ovarian drilling|OTHER: Bilateral laparoscopic ovarian drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Buccal Ginvigal Recessions With the Tunnel Technique in Conjunction With Cross-linked Hyaluronic Acid and Subepithelial Connective Tissue Graft. A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Cross-linked Hyaluronic Acid
Interventions: DEVICE: With Cross-linked Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab + Rituximab Consolidation in CLL
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Leukemia
Interventions: DRUG: Rituximab|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effects of Sildenafil on Patients With Fontan Heart Circulation
Status: COMPLETED
Conditions: Single Ventricle Heart Disease After Fontan Surgery
Interventions: DIAGNOSTIC_TEST: Cardiac catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Population-health management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-Response Study of Iocide Oral Rinse
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: Iocide Oral Rinse|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ixazomib in Adult Participants With Relapsed or Refractory Light Chain Amyloidosis
Status: COMPLETED
Conditions: Light-Chain Amyloidosis
Interventions: DRUG: Ixazomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot|Peripheral Arterial Disease|Diabetic Foot Ulcer|Peripheral Vascular Diseases|Peripheral Artery Disease|Critical Limb Ischemia|Critical Lower Limb Ischemia
Interventions: DIAGNOSTIC_TEST: Toe Brachial Pressure Index (TBPI)|DIAGNOSTIC_TEST: Ankle Brachial Pressure Index (ABPI)|DIAGNOSTIC_TEST: Exercise Ankle Brachial Pressure Index (ABPI)|DIAGNOSTIC_TEST: Audible handheld Doppler|DIAGNOSTIC_TEST: Visual handheld Doppler|DIAGNOSTIC_TEST: Podiatry Ankle Duplex scan (PAD-scan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability
Status: RECRUITING
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|Locally Advanced Solid Neoplasm|Metastatic Malignant Solid Neoplasm|POLD1 Gene Mutation|POLE Gene Mutation|Recurrent Malignant Solid Neoplasm|Recurrent Ovarian Carcinoma|Stage III Breast Cancer AJCC v7|Stage III Ovarian Cancer AJCC v8|Stage IIIA Breast Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIB Breast Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIC Breast Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v8|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation in Relapsed/Refractory T-, NK/T-cell Lymphomas
Status: RECRUITING
Conditions: T-cell Non-Hodgkin Lymphoma|Lymphoma, Extranodal NK-T-Cell
Interventions: DRUG: Busulfan|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of REGN475(SAR164877) in Patients With Pain Resulting From Thermal Injury
Status: WITHDRAWN
Conditions: Thermal Injury Pain
Interventions: DRUG: R475|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Inflammatory-dystrophic Diseases of the Cornea Using Autologous Stem Cells
Status: COMPLETED
Conditions: Corneal Ulcer|Corneal Disease|Corneal Dystrophy
Interventions: BIOLOGICAL: mesenchymal stem cells|BIOLOGICAL: limbal stem cells|OTHER: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cell Therapy in Patients With Relapsed or Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Vax-DC/MM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Clinical Trial of Uterine Transplantation in the United Kingdom
Status: UNKNOWN
Conditions: Infertility
Interventions: PROCEDURE: Oocyte retrieval and freezing|PROCEDURE: Deceased Donor Allograft Excision|PROCEDURE: Uterine Transplantation|DRUG: Immunosuppressive Agents|PROCEDURE: In-vitro fertilisation|PROCEDURE: Caesarean Section
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Multivitamins in Pediatric HIV Management in Nigeria
Status: UNKNOWN
Conditions: HIV
Interventions: DIETARY_SUPPLEMENT: Multivitamin A|DIETARY_SUPPLEMENT: Multivitamin B|DIETARY_SUPPLEMENT: Multivitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emotional Regulation and Impulsivity Among Adolescents With Borderline Personality Disorder
Status: UNKNOWN
Conditions: Borderline Personality Disorder|Adolescent Development
Interventions: OTHER: Clinical assessment|BEHAVIORAL: Stress elicitation experiment|OTHER: Structural and Functional MRI|BIOLOGICAL: salivary collections of amylase and cortisol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer
Status: RECRUITING
Conditions: Pediatric Cancer
Interventions: BEHAVIORAL: eSCCIP/eSCCIP-SP|BEHAVIORAL: Coping Space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora
Status: COMPLETED
Conditions: Intestinal Diseases|Helminthiasis
Interventions: DRUG: albendazole|DRUG: albendazole|DRUG: albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arrow Chloragard Peripherally-Inserted Central Catheters (PICC) Study
Status: UNKNOWN
Conditions: Vascular Access Complication|Vascular Access Related Infection
Interventions: DEVICE: Arrow PICC with Chloragard Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First in Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and to Explore Pharmacodynamics of BAY1834845
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease
Interventions: DRUG: BAY1834845|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does the Use of Ropivacaine Facilitates Cholecystectomy by Laparoscopy in Ambulatory Surgery?
Status: COMPLETED
Conditions: Cholecystectomy|Laparoscopy
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus
Status: TERMINATED
Conditions: Chronic Hepatitis|Hepatitis B
Interventions: DRUG: Clevudine|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Intervention for Mild Traumatic Brain Injury
Status: RECRUITING
Conditions: Concussion, Mild
Interventions: BEHAVIORAL: Mindfulness-Based Intervention|BEHAVIORAL: Cognitive Sham + Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
Status: RECRUITING
Conditions: Prostate Carcinoma|Recurrent Prostate Carcinoma
Interventions: DRUG: 99mTc-based PSMA Imaging and Surgery Agent|PROCEDURE: Computed Tomography|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair System
Status: ACTIVE_NOT_RECRUITING
Conditions: Tricuspid Valve Insufficiency
Interventions: DEVICE: Edwards PASCAL Transcatheter Valve Repair System|DEVICE: Edwards PASCAL Precision Transcatheter Valve Repair System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Safety and Pharmacokinetics (PK) of Ascending Single IV Doses of ERB-257 in Healthy Japanese Males
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ERB-257|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: TAS-102 in Combination With Regorafenib or Fruquintinib for Third-line and Above Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: TAS 102|Regorafenib|Fruquintinib|Gastrointestinal Tumours
Interventions: DRUG: regorafenib|DRUG: fruquintinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long Term Extension Study in Patients With Primary Hyperoxaluria
Status: ENROLLING_BY_INVITATION
Conditions: Primary Hyperoxaluria Type 1 (PH1)|Primary Hyperoxaluria Type 2 (PH2)|Kidney Diseases|Urologic Diseases|Genetic Disease|Primary Hyperoxaluria Type 3 (PH3)
Interventions: DRUG: DCR-PHXC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Giant Cell Arteritis (GCA)
Interventions: DRUG: Upadacitinib|DRUG: Corticosteroid (CS)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Progesterone and Preterm Birth in Twins
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: 200 mg of Progesterone|DRUG: 400 mg Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of Dexmedetomidine As Myocardial Protection In Pediatric Cyanotic Congenital Heart Disease Undergoing Open Cardiac Surgery Using Cardiopulmonary Bypass Machine: A Preliminary Study
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Cardiopulmonary Bypass
Interventions: DRUG: Placebo|DRUG: Dexmedetomidine Hcl 100 Mcg/mL Inj|DRUG: Dexmedetomidine Hcl 100 Mcg/mL Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablatherm Integrated Imaging High Intensity Focused Ultrasound for the Indication of Low Risk, Localized Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: Integrated Imaging High Intensity Focused Ultrasound|DEVICE: Endocare CRYOcare Cryosurgical and Galil Medical CRYO-HIT Systems (cryotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Randomized Comparison Between DES Limus Carbostent and Taxus DES in the Treatment of De-novo Coronary Lesions
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Documented Silent Ischemia
Interventions: DEVICE: DES Limus Carbostent|DEVICE: Taxus Liberté Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-Generated Quality of Life Assessment Program for Advanced Non-Small Cell Lung Cancer Patients (LUNL2)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Physician Receives QoL results|PROCEDURE: Physician Does not receive the results
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination of Neck Muscle Vibration and tDCS With Conventional Rehabilitation in Neglect Patients
Status: WITHDRAWN
Conditions: Unilateral Spatial Neglect
Interventions: DEVICE: Neck muscle vibration|DEVICE: Neck muscle vibration + sham-tDCS|DEVICE: Neck muscle vibration + anodal-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Treatments for Menopausal Women
Status: COMPLETED
Conditions: Menopause|Hot Flushes|Osteoporosis|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Red Clover extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Catheter Design on Catheter Survival in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Hemodialysis|Catheter Related Bloodstream Infection|Mechanical Catheter Dysfunction
Interventions: DEVICE: Tunneled Cuffed Catheter (Palindroom, Hemoglide Bard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Jing Si Herbal Tea on Physical and Psychological Symptoms in Peripheral Blood Hematopoietic Stem Cell Donors
Status: NOT_YET_RECRUITING
Conditions: Pain Syndrome|Emotional Stress
Interventions: OTHER: Jing Si Herbal Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of PD-1 Antibody and Bevacizumab in the Treatment of High-risk GTN After Combined Chemotherapy
Status: RECRUITING
Conditions: Gestational Trophoblastic Neoplasia
Interventions: DRUG: PD-1 inhibitor， bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Pharmacokinetics, Safety and Tolerability in Healthy Chinese Volunteers After Oral Doses of Saxagliptin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of AK159 in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: AK159|DRUG: MN-10-T|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Postpartum Insertion of Contraceptive Intrauterine Devices
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Kyleena Intrauterine System|DRUG: Mirena Intrauterine System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Telemedicine and Face-to-face Consultations Diagnostic Accuracy Comparison in Orthopedic Patients
Status: UNKNOWN
Conditions: Orthopedic Patients
Interventions: OTHER: Telemedicine Consultation with self orthopedic exam|OTHER: Face-to-face Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of α MAT Versus Steroid Injection in Knee Osteoarthritis (STα MAT-knee Study)
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Microfragmented Adipose Tissue Transplant|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Recruitment and Retention for Diabetes Self-Management Education and Support
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Technology|BEHAVIORAL: Standard DSMES Only|BEHAVIORAL: Traditional Recruitment Methods|BEHAVIORAL: CHW-Led Recruitment Methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Examine Plasma Concentrations of Buprenorphine Following Reapplication of Buprenorphine Transdermal System (BTDS) After Variable Application Site Rest Periods
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Buprenorphine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Stereotactic Hypofractionated Accelerated Radiotherapy Post-Prostatectomy
Status: UNKNOWN
Conditions: Prostate Cancer Adenocarcinoma|Adjuvant Radiotherapy|Salvage Radiotherapy|SBRT|IGRT|Urethral Sparing
Interventions: RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DRUG: Remifentanil|DRUG: Lidocaine|DRUG: Remifentanil+Lidocaine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Nab-Paclitaxel Plus S-1 in the First-line Treatment of Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Nab-paclitaxel and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ending Transmission of HIV, HCV, and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC)
Status: COMPLETED
Conditions: HIV|Hepatitis C|Opioid-use Disorder|Injection Drug Use
Interventions: BEHAVIORAL: Referral to harm reduction services
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Autonomic Nervous System (ANS) and Renal Function in Immunoglobin A (IgA) Nephropathy
Status: COMPLETED
Conditions: IGA Glomerulonephritis
Interventions: DEVICE: Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|BIOLOGICAL: Obinutuzumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of SCTV01C and SCTV01E (Two Recombinant Protein COVID-19 Vaccines) in Population Aged ≥12 Years
Status: WITHDRAWN
Conditions: COVID-19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: SCTV01C|BIOLOGICAL: SCTV01C|BIOLOGICAL: SCTV01C|BIOLOGICAL: SCTV01E|BIOLOGICAL: SCTV01E|BIOLOGICAL: SCTV01E|BIOLOGICAL: mRNA vaccine manufactured by Pfizer or Moderna|BIOLOGICAL: mRNA vaccine manufactured by Pfizer or Moderna|BIOLOGICAL: mRNA vaccine manufactured by Pfizer or Moderna|BIOLOGICAL: Sinopharm inactivated COVID-19 vaccine|BIOLOGICAL: Sinopharm inactivated COVID-19 vaccine|BIOLOGICAL: Sinopharm inactivated COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing 1 Week Versus 2 Week Cutaneous Suture Removal
Status: UNKNOWN
Conditions: Suture; Complications, Mechanical|Scar|Surgery
Interventions: PROCEDURE: Suture removal timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid-Based Parenteral Nutrition Improves Postoperative Recovery for Cirrhotic Patients With Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer|Cirrhosis
Interventions: DRUG: Omega-3 Fatty Acid-Based Parenteral Nutrition|DRUG: Structolipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxidative Stress and Inflammation Biomarkers in Surgically Treated Patients With Laryngeal Cancer
Status: RECRUITING
Conditions: Oxidative Stress Induction|Laryngeal Cancer|Interleukins|Pain Management|Quality of Life|Pain, Postoperative
Interventions: DRUG: Analgesics, Opioid|DRUG: Analgesics, Non-Narcotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial of Oral Naproxen and Transdermal Estradiol for Bleeding in LNG-IUC
Status: COMPLETED
Conditions: Contraception|Bleeding
Interventions: DRUG: transdermal estradiol|DRUG: naproxen|DRUG: oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Soft Tissue Loss With Nerve Defect in the Finger Using the Boomerang Nerve Flap
Status: COMPLETED
Conditions: Soft Tissue Loss With Nerve Defect
Interventions: PROCEDURE: the Boomerang Nerve Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
Status: RECRUITING
Conditions: Feeding and Eating Disorders
Interventions: OTHER: Test meal description changed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetics of SHP465 in Children Aged 4 to 5 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: SHP465
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Smoking Cessation and Pediatric Obesity Prevention
Status: RECRUITING
Conditions: Childhood Obesity|Smoking, Cigarette|Pregnancy
Interventions: BEHAVIORAL: Multicomponent behavioral intervention|BEHAVIORAL: Education only control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Liver Cancer
Interventions: DRUG: panobinostat|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2
Interventions: DRUG: Povidone-Iodine Nasal Spray and Gargle|DRUG: Povidone-Iodine Nasal Spray and Gargle|DRUG: Povidone-Iodine Nasal Spray and Gargle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Repeated Exposure to Antiseptics During COVID-19 Pandemic on Skin Parameters
Status: UNKNOWN
Conditions: Irritation/Irritant|ICD - Irritant Contact Dermatitis|Antiseptic
Interventions: OTHER: Emollient cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of H3B-6545 in Japanese Women With Estrogen Receptor (ER)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: H3B-6545|DRUG: Antihistamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Recurrent Vulvovaginal Candidiasis
Status: UNKNOWN
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: SHR8008|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEACON: HDR Brachytherapy, EBRT and STAD for the Treatment of Local and Pelvic Recurrence of Prostate Cancer After Radiation Therapy
Status: UNKNOWN
Conditions: Prostate Cancer - Recurrent
Interventions: RADIATION: HDR Brachytherapy + EBRT + STAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PROLONG Trial - Rituximab Maintenance Therapy in ITP
Status: ACTIVE_NOT_RECRUITING
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Dexamethasone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptation Dose of Enoxaparin in Moderate Renal Failure Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Renal Failure
Interventions: DRUG: dose adaptation of Enoxaparin|DRUG: normal injection of Enoxaparine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility, Acceptability, and Preliminary Efficacy of a Mobile App (nOCD) for OCD
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder (OCD)
Interventions: BEHAVIORAL: Therapist assisted mobile intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Equine Assisted Activities on PTSD, Quality of Life and Functioning in Veterans With PTSD: An ICF Approach (THRICF)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: OTHER: Therapeutic Horseback riding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Dinoprostone Administration Prior to an Intrauterine Device Insertion in Multiparous Women.
Status: COMPLETED
Conditions: IUD Insertion
Interventions: DRUG: Dinoprostone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NGS as the First-line Treatment in Advanced Biliary Tract Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: TS-1|DRUG: Gemcitabine|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Efficacy of DBT-A in Adolescents With Repetitive Self-harming and Suicidal Behaviours
Status: COMPLETED
Conditions: Intentional Self Harm
Interventions: BEHAVIORAL: Dialectical behavior therapy|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting
Status: COMPLETED
Conditions: Blood Transfusion|Endothelial Physiopathology|Nitric Oxide|Pulmonary Hypertension
Interventions: PROCEDURE: Red blood Cells auto-transfusion|PROCEDURE: Red blood Cells auto-transfusion|DRUG: Inhaled Nitric Oxide (iNO) administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma With High Predict Risk of Lymph Node Metastasis
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma Recurrent
Interventions: DRUG: Neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intensive Chiropractic Care to Usual Care for Children With Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Sham intervention|OTHER: Chiropractic Care|OTHER: Physical therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trueness of Full Arch Scans and Generated Digital Implant Models
Status: NOT_YET_RECRUITING
Conditions: Denture|Complete Edentulism
Interventions: DEVICE: conventional impression stone casts digitization|DEVICE: digital scanning with coupled scanning aiding device|DEVICE: Digital Implant Model assessment of accuracy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RHPRG4 FOR THE TREATMENT OF SJÖGREN'S RELATED DRY EYE DISEASE
Status: NOT_YET_RECRUITING
Conditions: Sjogren's Syndrome With Dry Eye
Interventions: DRUG: rhPRG4 (450 µg/mL)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
Status: RECRUITING
Conditions: Urinary Incontinence, Urge
Interventions: DEVICE: CAN-Stim - Protect CAN-Stim System|DEVICE: SNS - InterStim® System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma
Status: RECRUITING
Conditions: Lymphoma, Follicular
Interventions: DRUG: Golcadomide|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis
Status: COMPLETED
Conditions: Alveolitis|Systemic Sclerosis
Interventions: DRUG: Imatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastroparesis Registry 4
Status: NOT_YET_RECRUITING
Conditions: Gastroparesis|Gastroparesis Nondiabetic|Gastroparesis Due to Diabetes Mellitus Type I|Gastroparesis Due to Diabetes Mellitus Type II|Functional Disorder of Gastrointestinal Tract|Gastro-Intestinal Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Darolutamide in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Hormone-sensitive Prostate Cancer
Interventions: DRUG: BAY1841788 / darolutamide (ODM-201)|DRUG: Standard ADT (androgen deprivation therapy)|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
Status: RECRUITING
Conditions: Blood Pressure|Low Back Pain|Hypertension
Interventions: DEVICE: Permanent Epidural Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The InterSat Study
Status: COMPLETED
Conditions: Cardiometabolic Health
Interventions: DIETARY_SUPPLEMENT: Palmitic acid rich interesterified fat|DIETARY_SUPPLEMENT: Stearic acid rich interesterified fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: TAR-200|BIOLOGICAL: Cetrelimab|BIOLOGICAL: BCG Vesiculture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCM for Post-operative Edema
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DEVICE: LASER acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Oral Vitamin D3|RADIATION: Ultraviolet Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Iloperidone Compared With Placebo and Active Control in Subjects With Acute Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: iloperidone|DRUG: active comparator|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People
Status: RECRUITING
Conditions: Hypertension,Essential|Hypertension
Interventions: OTHER: Group control|OTHER: Isometric Exercise|OTHER: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of APX005M in Pediatric CNS Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme|High-grade Astrocytoma NOS|CNS Primary Tumor, Nos|Ependymoma, NOS|Diffuse Intrinsic Pontine Gliomas (DIPG)|Medulloblastoma
Interventions: BIOLOGICAL: APX005M treatment for recurrent or refractory primary malignant CNS tumor patients|BIOLOGICAL: APX005M treatment for newly diagnosed DIPG patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Analgesic Efficacy and Safety of VM902A in Subjects With Osteoarthritis (OA) of the Knee
Status: TERMINATED
Conditions: Osteoarthritis Pain of the Knee
Interventions: DRUG: VM902A 200-mg Capsules|DRUG: VM902A 400-mg Capsules|DRUG: Naproxen 500-mg Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy
Status: RECRUITING
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: OTHER: Blood sampling and urine analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Zirconium Cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Proportion to Roadmap Concept in Patients With HBV Associated-HCC
Status: COMPLETED
Conditions: Hepatitis B Associated Hepatocellular Carcinoma
Interventions: DRUG: clevudine, Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Local Anesthesic on Diaphragmatic Function After Upper Abdominal Surgery
Status: COMPLETED
Conditions: Hepatectomy
Interventions: PROCEDURE: Sniff test|DRUG: Infusion of Ropivacaine during 48 hours|DEVICE: Continuous parietal infusion with parietal catheter|DRUG: Infusion of placebo during 48 hours|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Human umbilical cord mesenchymal stem cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UTSW HP [13-C] Pyruvate Injection in HCM
Status: RECRUITING
Conditions: Cardiomyopathy, Hypertrophic|Dilated Cardiomyopathy|Duchenne Muscular Dystrophy|Cardiac Sarcoidosis|Becker Muscular Dystrophy|Heart Failure With Preserved Ejection Fraction|Heart Failure With Reduced Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Hyperpolarized 13C-Pyruvate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Walking After Traumatic Brain Injury in Older Adults
Status: RECRUITING
Conditions: Traumatic Brain Injury|TBI|Mild Traumatic Brain Injury|Moderate Traumatic Brain Injury
Interventions: OTHER: Planning, Reminders, and Micro-Incentives|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Effectiveness Study of JNJ-18038683 in Patients With Moderate to Severe Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Escitalopram|DRUG: JNJ-18038683
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Safety & Immunogenicity of Stored Inactivated Influenza H5N1 Virus Vaccine Given With & Without Stored MF59 Adjuvant
Status: COMPLETED
Conditions: A/Vietnam/H5N1 Influenza Virus
Interventions: BIOLOGICAL: 7.5 mcg H5N1 (stored as monobulk)|BIOLOGICAL: 15 mcg H5N1 (stored as monobulk)|BIOLOGICAL: 90 mcg H5N1 (stored as monobulk)|BIOLOGICAL: 90 mcg H5N1 (stored in vials)|OTHER: MF59|OTHER: MF59 (stored as monobulk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Pralatrexate|DRUG: Erlotinib|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies
Status: UNKNOWN
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Acute Lymphoblastic Lymphoma|Acute Myeloid Leukemia|NK Cell Lymphoma
Interventions: BIOLOGICAL: CD7-specific CAR gene-engineered T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor (Ruxolitinib; INBC018424) in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ruxolitinib 25 mg|DRUG: Dexamethasone 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serology After BBIBP-CorV Inactivated Vaccine Combined With BNT62b2 mRNA Booster Vaccine
Status: COMPLETED
Conditions: Basic BBIBP-CorV Vaccination is Not as Effective as BNT162b
Interventions: BIOLOGICAL: BBIBP-CorV and/or BNT162b2 vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ⅱ Clinical Study of 9MW1411 Injection in Acute Bacterial Skin and Skin Structure Infections
Status: UNKNOWN
Conditions: Skin Infection
Interventions: COMBINATION_PRODUCT: 9MW1411 injection 1 combined with Linezolid|COMBINATION_PRODUCT: 9MW1411 injection 2 combined with Linezolid|COMBINATION_PRODUCT: 9MW1411 injection placebo combined with Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Delamanid, Bedaquiline, OPC-167832, and Sutezolid (DBOS)|DRUG: Pretomanid, Bedaquiline, OPC-167832, and Sutezolid (PBOS)|DRUG: Isoniazid, Rifampicin, Pyrazinamide, Ethambutol (HRZE)|DRUG: Pretomanid or Delamanid, Bedaquiline, OPC-167832, and Sutezolid (XBOS)|DRUG: Isoniazid and Rifampicin (HR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT