pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The COMBAT HBV Feasibility Trial
Status: RECRUITING
Conditions: Hepatitis B|Vertical Transmission of Infectious Disease
Interventions: DRUG: Tenofovir Disoproxil Fumarate 300 MG|BIOLOGICAL: Hepatitis B monovalent vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: DRUG: NOAC|DRUG: DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravesical Injection of Botulinum Toxin A Versus Saline for Neurogenic Detrusor Overactivity
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity
Interventions: DRUG: Botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Obesity|Gastroparesis
Interventions: DRUG: Semaglutide|DRUG: Tirzepatide|DRUG: Liraglutide|DRUG: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Taping and Patellar Maltraction in PFPS Patients
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Exercise program|OTHER: McConnel patellar taping technique|OTHER: Femoral rotational taping technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Moxibustion for Diarrhea-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: moxibustion|DEVICE: Sham moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy|Diabetic Neuropathy|Neuropathy
Interventions: DRUG: Clonidine Gel 0.1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|Alcohol Use Disorder
Interventions: DRUG: Ketamine + Naltrexone|DRUG: Ketamine + Placebo|DRUG: Placebo (psychoactive placebo midazolam) + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MRG-001 in Wound Healing in Abdominoplasty Patients
Status: RECRUITING
Conditions: Wound of Skin|Abdominal Wound
Interventions: DRUG: MRG-001|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Daily Ulipristal Acetate and Combined Oral Contraceptive Effects on Breast Epithelial Cell Proliferation
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Ulipristal Acetate|DRUG: Combined Oral Contraceptive Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The First Line Treatment of Fruquintinib Combined With Albumin Paclitaxel and Gemcitabine in Pancreatic Cancer Patients
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Fruquintinib,Albumin Paclitaxel,Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Implementation of a Family Therapy Intervention ("Tuko Pamoja") Delivered Through Sexual and Reproductive Healthcare Settings
Status: COMPLETED
Conditions: Family Conflict|Family Dysfunctional|Adolescent Behavior|Child Behavior|Marital Conflict|Domestic Violence|Parent-Child Relations
Interventions: BEHAVIORAL: Tuko Pamoja
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lithium Carbonate on Postoperative Sleep and Cognitive Function in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Heart Valve Surgery
Interventions: DRUG: Lithium Carbonate 250 MG Oral Tablet|DRUG: Calcium Carbonate 500 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Diagnosis and Treatment of Dorsal Wrist Syndrome in Patients With Synovial Hypertrophy
Status: UNKNOWN
Conditions: Synovial Hypertrophy Hand (Diagnosis)
Interventions: PROCEDURE: arthroscopic synovectomy and thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reading a Pictorial Storybook on Children's Fear, Anxiety and Emotional Symptoms Before Dental Treatment
Status: NOT_YET_RECRUITING
Conditions: Dental Fear
Interventions: OTHER: Reading a Pictorial Storybook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Digestive System Diseases|Colonic Diseases, Functional|Colitis, Mucous|Colon, Irritable
Interventions: DIETARY_SUPPLEMENT: Kyodophilus multi-strain probiotic capsules|DIETARY_SUPPLEMENT: Kyodophilus Matching Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir and Daclatasvir for Treating Hepatitis C in 200 Patients Co-infected With Human Immunodeficiency Virus
Status: COMPLETED
Conditions: Hepatitis C Virus Infection, Response to Therapy of|Human Immunodeficiency Virus
Interventions: DRUG: sofosbuvir and daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Consumption of Pep19 on Quality of Life
Status: ACTIVE_NOT_RECRUITING
Conditions: Quality of Life|Obesity|Sleep Quality
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Pep19 2 mg|DIETARY_SUPPLEMENT: Pep19 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Phase 1/2 Study of HQK-1001 in Patients With Beta Thalassemia
Status: COMPLETED
Conditions: Beta Thalassemia
Interventions: DRUG: HQK-1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone.
Status: RECRUITING
Conditions: Liposarcoma, Myxoid|Liposarcoma, Dedifferentiated|Liposarcoma, Round Cell
Interventions: DRUG: Trabectedin|DRUG: Pioglitazone Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal Hyaluronic Acid Treatment Over Autologous Platelet Rich Plasma Treatment for Genitourinary Syndrome of Menopause
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: BIOLOGICAL: Platelet Rich Plasma treatment|DRUG: Vaginal Hyaluronic Acid supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anterior Abdominal Blocks for Postoperative Pain Control in Obese Patients
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Surgical Transversus Abdominis Plane Block|PROCEDURE: Surgical Rectus Sheath Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of Insulin Glargine 300 U/ml (Gla-300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus Uncontrolled on Oral Antihyperglycemic Drugs
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine (U300)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study of JS203 in Patients With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: JS203 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canakinumab Study in Individuals With Newly Diagnosed Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Preservation of Insulin Secretion|Newly Diagnosed Type 1 Diabetes|Canakinumab in Type 1 Diabetes
Interventions: DRUG: canakinumab (anti IL-1beta)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypogonadotropic Hypogonadism in Obese Young Males
Status: TERMINATED
Conditions: Hypogonadism, Hypogonadotropic
Interventions: DRUG: Clomiphene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)
Status: RECRUITING
Conditions: Untreated Advanced or Recurrent Thymic Carcinomas
Interventions: DRUG: MK-3475|DRUG: Lenvatinib|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of the Combination of Anlotinib With Gefitinib
Status: UNKNOWN
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of Biomarkers of Tobacco Exposure, Urge-to-Smoke Following Exclusive and Dual Ad Lib Use of Electronic Cigarettes
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: OTHER: Exclusive blu™ e-cigarette A1|OTHER: Exclusive blu™ e-cigarette A2|OTHER: Exclusive blu™ e-cigarette A3|OTHER: Dual blu™ e-cigarette and usual brand B1|OTHER: Dual blu™ e-cigarette and usual brand B2|OTHER: Dual blu™ e-cigarette and usual brand B3|OTHER: Nicotine product cessation C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers of Developmental Trajectories and Treatment in Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Children at Risk for ASD
Interventions: BEHAVIORAL: Baby JASPER|BEHAVIORAL: Standard Baby Classroom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Research on the Clinical Effect of Shuanghe Decoction in Treating Unstable Angina.
Status: UNKNOWN
Conditions: Unstable Angina
Interventions: DRUG: Anti-Platelet Drugs|DRUG: Lipid Regulating Drugs|DRUG: Coronary Vasodilator|DRUG: Shuanghe Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phase I Clinical Study to Evaluate the Pharmacokinetics of Dw1029M in Healthy Male Volunteer
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: DW1029M300mg|DRUG: DW1029M600mg|DRUG: DW1029M1200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Satiety Study of a Carbohydrate Meal to a Highly Viscous Gel Meal
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Konjac noodles|DIETARY_SUPPLEMENT: Carbohydrate and Konjac Noodles|DIETARY_SUPPLEMENT: Carbohydrate noodles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-Flow-Therapy for the Treatment of Cheyne-Stokes-Respiration in Chronic Heart Failure
Status: TERMINATED
Conditions: Heart Failure，Congestive
Interventions: DRUG: Oxygen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Palmitoleic Acid on C-reactive Protein
Status: COMPLETED
Conditions: Chronic Inflammation|Overweight
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Palmitoleic acid, 500 mg (Dose 1)|DIETARY_SUPPLEMENT: Palmitoleic acid, 1,000 mg (Dose 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: triacetyluridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Short-term Effect of L-Citrulline on Endothelial Function and Vasodilation in Known CAD Patients
Status: UNKNOWN
Conditions: Vascular Disease
Interventions: DRUG: L-Citrulline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC.
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Chidamide|DRUG: Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economics to Improve Flu Vaccination Using EHR Nudges
Status: COMPLETED
Conditions: Behavior, Health|Flu|Flu Vaccination
Interventions: BEHAVIORAL: Pre-visit patient text messaging|BEHAVIORAL: Default pended order|BEHAVIORAL: Monthly peer comparison feedback|BEHAVIORAL: High risk bidirectional pre-visit text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma
Status: RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Locally Advanced Cutaneous Melanoma|Metastatic Cutaneous Melanoma|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Unresectable Cutaneous Melanoma
Interventions: DRUG: Binimetinib|BIOLOGICAL: Nivolumab|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of a Bivalent Vaccine of New 6:2 Influenza Virus Reassortants in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluMist|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1019" and Co-administration of "BR1019-1" and "BR1019-2"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Essential Hypertension
Interventions: DRUG: BR1019|DRUG: BR1019-1|DRUG: BR1019-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: M5049 low dose|DRUG: M5049 medium dose|DRUG: M5049 high dose|DRUG: Placebo|DRUG: M5049 very high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evolving Methods to Combine Cognitive and Physical Training for Individuals With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Microbiota and Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Fatigue Syndrome, Chronic|Microbial Colonization
Interventions: PROCEDURE: Faecal transplantation|PROCEDURE: Placebo faecal transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: Granexin gel|OTHER: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation Combined With Chemotherapy for Colorectal Liver Metastases： a Multicenter Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Colorectal Carcinoma|Chemotherapy|Liver Metastases
Interventions: DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TPC+Apatinib+Camrelizumab vs GP+ Camrelizumab for High-Risk Nasopharyngeal Carcinoma: A Phase 3 Trial
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TPC combined with Apatinib and Camrelizumab|DRUG: GP Combined With Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mentored Research on Improving Alcohol Brief Interventions in Medical Settings
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: BEHAVIORAL: Brief Advice|BEHAVIORAL: NIAAA Clinician's Guide|BEHAVIORAL: Motivational Interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study of Diagnostic Accuracy of Spectral CT for the Detection of Bone Marrow Edema
Status: RECRUITING
Conditions: Fractures, Bone|Bone Marrow Edema
Interventions: DIAGNOSTIC_TEST: Computed Tomography of the skeleton using a Dual-Energy-/Multi-Energy-/Spectral acquisition mode|DIAGNOSTIC_TEST: Computed Tomography of the skeleton using a conventional single-energy / non-spectral acquisition mode
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thalidomide Results in Diminished Ovarian Reserve in Reproductive Age Female IBD Patients
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: Thalidomide|DRUG: infliximab, azathioprine|OTHER: enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Peas in Chili on Blood Glucose and Appetite Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-prandial Glycaemic Response|Satiety
Interventions: DIETARY_SUPPLEMENT: Whole yellow pea chili|DIETARY_SUPPLEMENT: Split yellow pea chili|DIETARY_SUPPLEMENT: Rice chili
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Metronidazole gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Imiquimod and Diclofenac in Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin Combined With Fluorouracil and Leucovorin in Treating Patients With Recurrent or Metastatic Cancer of the Esophagus or Stomach
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Promotion of Timely Delivery
Status: COMPLETED
Conditions: Delivery, Obstetric
Interventions: PROCEDURE: Acupuncture|DEVICE: Non-puncturing Acupuncture Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Status: COMPLETED
Conditions: Anesthesia Intubation Complication|Tracheal Disease
Interventions: DRUG: Ketorolac|OTHER: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preference Attributes of ELLIPTA Dry Powder Inhaler (DPI) and HANDIHALER DPI in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo ELLIPTA device|DRUG: Placebo capsules for use in HANDIHALER device|OTHER: Inhaler Preference Questionnaire Version 1|OTHER: Inhaler Preference Questionnaire Version 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Mobile App on Improving Asthma Control in Patients With Persistent Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DEVICE: InspirerMundi app|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine (RSV LID cp ΔM2-2) in RSV-Seronegative Infants and Children 6 to 24 Months of Age
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV LID cp ΔM2-2 Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve
Status: UNKNOWN
Conditions: Optic; Neuritis, With Demyelination
Interventions: DRUG: Amiloride hydrochlorothiazide|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Azithromycin/Chloroquine|DRUG: Atovaquone/Proguanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Home Based Personalized Training and Video Consultation in Mitochondrial Myopathies: Study of Efficacy and Tolerance.
Status: RECRUITING
Conditions: Mitochondrial Myopathies
Interventions: PROCEDURE: Personalized and mixed training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: County Medical Community-based, Cardiovascular Risk Stratified Integrated Care Model: a Pragmatic Cluster Randomised Control Trial
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Diabetes Mellitus Type 2|Cardiovascular Diseases
Interventions: OTHER: Team-based care|PROCEDURE: Risk-stratified care pathway|BEHAVIORAL: Strengthened health education|OTHER: Financial incentives for integration of care|OTHER: Supporting health information system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial on the Candidate Vaccine cAd3-EBOZ in Healthy Adults in Switzerland
Status: COMPLETED
Conditions: Ebola Vaccines
Interventions: BIOLOGICAL: cAd3-EBOZ vaccine|BIOLOGICAL: Placebo (for cAd3-EBOZ vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zr89 + PET Companion Trial
Status: ENROLLING_BY_INVITATION
Conditions: Melanoma (Skin)
Interventions: DRUG: Zirconium Zr 89 Crefmirlimab Berdoxa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutraceutical Combination in Patients With Low-grade Systemic Inflammation
Status: COMPLETED
Conditions: Atherosclerosis|Inflammation|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Nutraceutical Combination|OTHER: Standard of Care|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion
Status: NOT_YET_RECRUITING
Conditions: Pleural Effusion, Malignant
Interventions: DIAGNOSTIC_TEST: pleural markers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ozurdex for Macular Edema Post Membrane Peeling
Status: COMPLETED
Conditions: Epiretinal Membrane|Cellophane Maculopathy|Macular Edema|Retinal Edema
Interventions: DRUG: Dexamethasone|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Duration of Symptoms on the Clinical and Functional Outcomes of Lumbar Microdiscectomy
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: PROCEDURE: Lumbar Microdiscectomy at 6 weeks of symptoms|PROCEDURE: Lumbar Microdiscectomy at 3 months of symptoms|PROCEDURE: Lumbar Microdiscectomy at 6 months of symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Recombinant Human Follicle Stimulating Hormone Fc Husion Protein (KN015) in Healthy Volunteers
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: KN015|DRUG: Placebo|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Communicating Human Papillomavirus Vaccine With Japanese Parents and Caregivers With Daughters Aged 12-18
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: BEHAVIORAL: Group 1 (I x S x S x F)|BEHAVIORAL: Group 2 (O x S x S x F)|BEHAVIORAL: Group 3 (I x E x S x F)|BEHAVIORAL: Group 4 (O x E x S x F)|BEHAVIORAL: Group 5 (I x S x S x M)|BEHAVIORAL: Group 6 (O x S x S x M)|BEHAVIORAL: Group 7 (I x E x S x M)|BEHAVIORAL: Group 8 (O x E x S x M)|BEHAVIORAL: Group 9 (I x S x D x F)|BEHAVIORAL: Group 10 (O x S x D x F)|BEHAVIORAL: Group 11 (I x E x D x F)|BEHAVIORAL: Group 12 (O x E x D x F)|BEHAVIORAL: Group 13 (I x S x D x M)|BEHAVIORAL: Group 14 (O x S x D x M)|BEHAVIORAL: Group 15 (I x E x D x M)|BEHAVIORAL: Group 16 (O x E x D x M)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: OTHER: Interleukin 28B testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor
Status: TERMINATED
Conditions: Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Unresectable Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Pevonedistat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of the Early Referral and Request Approach (ERRA) Intervention to Increase Consent to Organ Donation
Status: COMPLETED
Conditions: Organ Donation
Interventions: BEHAVIORAL: Assisted CEaD Condition|BEHAVIORAL: Autonomous CEaD Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trail of a Novel Tracheal Radioactive Stent for the Malignant Airway Obstruction
Status: UNKNOWN
Conditions: Malignant Airway Obstruction
Interventions: DEVICE: Traditional airway stent|DRUG: Iodine-125 seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ARRY-438162 (MEK162) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors|Advanced or Metastatic Biliary Cancer|Metastatic Colorectal Cancer
Interventions: DRUG: ARRY-438162 (MEK162), MEK inhibitor; oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Recombinant Zoster Vaccine (Adenovirus Vector) (ChAdOx1-VZV)|BIOLOGICAL: Zoster Vaccine Recombinant, Adjuvanted (Shingrix)|BIOLOGICAL: ChAdOx1-VZV|BIOLOGICAL: Shingrix|BIOLOGICAL: IH ChAdOx1-VZV|BIOLOGICAL: IH saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cisplatin With Gemcitabine With Dexamethasone in Patients With Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: gemcitabine|DRUG: cisplatin|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: BL-8040|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Thermal Stimulation on Upper Extremity Motor Recovery to Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: A custom-made constant temperature thermal stimulation system (FIRSTEK, Model-B401L, B-300, local company, Taiwan).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer of Fresh Versus Frozen/Thawed Embryos in IVF Cycles Where GnRH Agonist is Utilized for Oocyte Maturation.
Status: WITHDRAWN
Conditions: Ovarian Hyperstimulation Syndrome|Infertility Drugs|Female
Interventions: PROCEDURE: Delayed embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: CNTO 6785 200 mg|DRUG: CNTO 6785 200 mg|DRUG: CNTO 6785 100 mg|DRUG: CNTO 6785 50 mg|DRUG: CNTO 6785 15 mg|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of Myoblasts
Status: COMPLETED
Conditions: Muscular Dystrophy, Oculopharyngeal
Interventions: PROCEDURE: Autologous myoblasts transplantation and myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Dovitinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Treatment Failure
Interventions: DRUG: Lansoprazole|DRUG: Bismuth Potassium Citrate|DRUG: Metronidazole|DRUG: Amoxicillin|DRUG: Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: Glucagon for Injection (Fresenius Kabi USA)|DRUG: Glucagon for Injection (Bedford Laboratories)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Bevacizumab Plus Chemotherapy in Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Xeloda|DRUG: Calcium folinate (CF)|DRUG: 5-FU|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: p53 Vaccine for Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasm
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: p53 peptide vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous dendritic cells|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Difficult Airways Scores Validation Difficult Laryngoscopy and Mask Ventilation: Prospective and Evaluative Study
Status: NOT_YET_RECRUITING
Conditions: Airway Complication of Anesthesia|Ultrasound|Laryngoscopy|Difficult Airways
Interventions: DIAGNOSTIC_TEST: upper airway sonography|DIAGNOSTIC_TEST: upper airway sonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Explore the Efficacy and Safety of Atezolizumab Plus Tiragolumab and Chemotherapy in 1st Line HER2 Negative Unresectable, Recurrent or Metastatic Gastric Cancer or Adenocarcinoma of Gastroesophageal Junction (GEJ)
Status: TERMINATED
Conditions: Stomach Neoplasms|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery
Status: UNKNOWN
Conditions: Intracranial Meningioma|Neurologic Deficits
Interventions: BIOLOGICAL: HBOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Controlled Trial on the Use of Cerebral Oximetry in Adult Chinese Patients Undergoing Liver Transplantation
Status: UNKNOWN
Conditions: Liver Failure
Interventions: OTHER: Cerebral oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effects of a Mobile Health Intervention and Health Coach Text Messaging on Cardiovascular Risk of Older Adults
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Get FIT|BEHAVIORAL: Get FIT+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyaluronan-enriched Embryo Transfer Medium for Frozen-thawed Embryo Transfer
Status: COMPLETED
Conditions: In Vitro Fertilization|Subfertility
Interventions: OTHER: EmbryoGlue (Vitrolife)|OTHER: Control medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Molecular Epidemiology Study in Singapore Patients With Advanced Non Small Cell Lung Cancer (NSCLC) of Adenocarcinoma Histology to Assess Epidermal Growth Factor Receptor (EGFR) Mutation Status
Status: UNKNOWN
Conditions: NSCLC
Interventions: OTHER: EGFR mutation status in patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BUCYE Conditioning Regimen for PCNSL Undergoing Auto-HSCT
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma|Autologous Hematopoietic Stem Cell Transplantation|Conditioning
Interventions: DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)|DRUG: Etoposide (VP-16)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Visual Instructions for Inserting a Laryngeal Mask in a Neonatal Mannequin.
Status: NOT_YET_RECRUITING
Conditions: Cardiopulmonary Resuscitation|Newborn Asphyxia
Interventions: OTHER: Instructions A|OTHER: Instructions B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Twelve Week Study to Investigate the Efficacy of Femarelle®, for the Treatment of Post Menopausal Vaginal Atrophy
Status: COMPLETED
Conditions: Vulvo Vaginal Atrophy
Interventions: DIETARY_SUPPLEMENT: Femarelle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in the Renal Excretion of Neramexane by Acidification of Urinary pH Study With and Without Application of a Urinary pH Acidification Regimen
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Neramexane
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Infrared Photomodulation for Hormonal Balance (Joovvin' for Hormonal Health)
Status: UNKNOWN
Conditions: Testosterone Deficiency|Estrogen Deficiency
Interventions: DEVICE: Joovv Infrared Light Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Saliva Analysis After Low-level Laser Therapy Application on the Masseter Muscle Located Above Parotid Salivary Gland
Status: UNKNOWN
Conditions: Saliva Altered
Interventions: RADIATION: Low level laser therapy|OTHER: Placebo|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma
Status: COMPLETED
Conditions: Malignant Brain Tumor|Brain Stem Glioma,
Interventions: DRUG: Tarceva (Erlotinib Hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Cohort for the Study of the Effect of CPAP in Hypertension (CEPECTA)
Status: UNKNOWN
Conditions: Sleep Apnea|Hypertension
Interventions: DEVICE: Nasal continuos positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Single Arm, Open-label First In Human Study for Assessing the Safety and Performance of the EpiFinder in Subjects With Clinical Indication for Lumbar Epidural Steroids Injection (ESI)
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DEVICE: EpiFinder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Honey-flavored Yogurt on Low-grade Inflammation and Gut Health in Middle to Older Aged Women.
Status: RECRUITING
Conditions: Overweight
Interventions: OTHER: Honey sweetened yogurt|OTHER: Sugar sweetened yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults
Status: COMPLETED
Conditions: Dietary Supplement|Placebo
Interventions: DIETARY_SUPPLEMENT: beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Hyaluronic Acid (UltraHA®) on the Knee Function
Status: COMPLETED
Conditions: Healthy Japanese Subjects
Interventions: DIETARY_SUPPLEMENT: UltraHA® 75 mg/capsule|DIETARY_SUPPLEMENT: UltraHA® 40 mg/capsule|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of PTSD Treatment With Computerized Executive Function Training
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Computerized executive function training plus CPT (CEFT-CPT)|BEHAVIORAL: Word game training plus CPT (WT-CPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Evaluate the Safety and Efficacy of Avatrombopag and Remission Rates in Adults With ITP of ≤6 Months
Status: WITHDRAWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Avatrombopag 20 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT