pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Surgical Decompression Associated With Physical Therapy and Physical Therapy Isolated in Patients With Lumbar Stenosis.
Status: COMPLETED
Conditions: LUMBAR STENOSIS
Interventions: PROCEDURE: LUMBAR DESCOMPRESSION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thymoglobulin Versus Campath-1H Versus Daclizumab in Adult, Primary Deceased Donor Renal Transplantation
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Thymoglobulin|DRUG: Campath-1H|DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer
Status: RECRUITING
Conditions: Mesonephric Gynecologic Cancer
Interventions: DRUG: Avutometinib (VS-6766)|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS)
Status: COMPLETED
Conditions: Basal Cell Carcinoma in Basal Cell Nevus Syndrome
Interventions: DRUG: SUBA-Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Impact of High-protein Oral Supplement on Protein Status of Adults on Peritoneal Dialysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Failure|Protein-Energy Malnutrition
Interventions: DIETARY_SUPPLEMENT: Whey protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Incentive Spirometry Added to Routine Physiotherapy Program on Hemodynamic Responses and Hospital Stay in Patients With COPD Exacerbation
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: OTHER: Conventional Chest Physiotherapy|OTHER: Conventional Chest Physiotherapy+Incentive Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance of Junctional Tourniquets in Normal Human Volunteers
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DEVICE: CRoC|DEVICE: AAJT|DEVICE: JETT|DEVICE: SJT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Unilateral Ultrasound Guided Paravertebral Block as Perioperative Analgesia For Lower Limb-Sparing Surgery In Adult Cancer Patients
Status: COMPLETED
Conditions: Unilateral U/S PVB
Interventions: DRUG: Paravertebral group (group P):
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums
Status: RECRUITING
Conditions: Recession, Gingival
Interventions: PROCEDURE: Mandibular Incisor root coverage procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Cranial Electrostimulating Therapy for Depression and Anxiety Among Homeless Adults
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: DEVICE: Alpha Stim device|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing the Contribution of Orbitofrontal Cortex Networks to Reward Identity Learning
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Sham transcranial magnetic stimulation (TMS)|DEVICE: Real transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Assessment of Giomer Based Technology Versus Smart Bioactive Restoration in Carious Class V Cavities
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Beautifil Flow Plus X.|PROCEDURE: Activa bioactive restorative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FX006 in Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: FX006|DRUG: TCA IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Metastatic Cancer|Neuroblastoma
Interventions: PROCEDURE: surgical procedure|RADIATION: astatine At 211 monoclonal antibody 81C6
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Cardiac Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Malignant Tumor
Status: SUSPENDED
Conditions: Advanced Malignant Tumor
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engaging Adolescents in Decisions About Return of Genomic Research Results
Status: ACTIVE_NOT_RECRUITING
Conditions: Genetic Screening|Adolescent|Genetic Change|Shared Decision Making|Knowledge, Attitudes, Practice|Genetic Testing
Interventions: GENETIC: Electronic Decision Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
Status: TERMINATED
Conditions: Childhood Choroid Plexus Tumor|Childhood Ependymoblastoma|Childhood Grade III Meningioma|Childhood High-grade Cerebellar Astrocytoma|Childhood High-grade Cerebral Astrocytoma|Childhood Medulloepithelioma|Recurrent Childhood Anaplastic Astrocytoma|Recurrent Childhood Anaplastic Oligoastrocytoma|Recurrent Childhood Anaplastic Oligodendroglioma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Giant Cell Glioblastoma|Recurrent Childhood Glioblastoma|Recurrent Childhood Gliomatosis Cerebri|Recurrent Childhood Gliosarcoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Pineoblastoma|Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions: DRUG: palbociclib isethionate|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Strategies to Present Colon Cancer Screening Information
Status: COMPLETED
Conditions: Colonic Neoplasms|Colorectal Neoplasms|Colonic Diseases|Gastrointestinal Neoplasms
Interventions: BEHAVIORAL: Health communication intervention|BEHAVIORAL: Education information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor
Status: COMPLETED
Conditions: Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member|Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndrome|Chronic Myelogenous Leukemia|Non-Hodgkin's Lymphoma|Hodgkin's Disease|Chronic Lymphocytic Leukemia
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HuHuangLianzonggan Capsule in Subjects With Nonalcoholic Steatohepatitis: a Phase 2 tRial(HHL-HEPAR)
Status: RECRUITING
Conditions: NASH
Interventions: DRUG: HuHuangLianzonggan capsule|DRUG: HuHuangLianzonggan capsule placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations
Status: COMPLETED
Conditions: Ocular Hypertension|Open-angle Glaucoma
Interventions: DRUG: Timolol and Tafluprost|DRUG: Fixed Dose Combination of tafluprost and timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Global Study to Assess the Effects of MEDI4736 Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: MEDI4736|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arresting Early Childhood Caries With a Silver Diamine Fluoride Gel
Status: RECRUITING
Conditions: Early Childhood Caries
Interventions: DRUG: Silver diamine fluoride gel|DRUG: Silver diamine fluoride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osteoradionecrosis Rate in Patients Undergoing Radiotherapy for Head and Neck Cancer Treatment.
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Osteoradionecrosis|Radiotherapy Side Effect|Tooth Avulsion
Interventions: PROCEDURE: Tooth extraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glass Hybrid Versus Composite Restorations of Non-carious Cervical Lesions
Status: COMPLETED
Conditions: Dental Cervical Non-carious Lesion
Interventions: OTHER: Equia Forte|OTHER: Filtek Supreme XT/Clearfil SE Bond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KEEPS Mammographic Density And Breast Health Ancillary Study
Status: COMPLETED
Conditions: Mammographic Density|Abnormal Mammogram
Interventions: DRUG: CEE pill|DRUG: Estradiol patch|DRUG: Active Progesterone|OTHER: Placebo tablet|OTHER: Placebo patch|OTHER: Placebo progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Compare the Pharmacokinetics of Avanafil in Subjects With Mild and Moderate Renal Impairment to Subjects With Normal Renal Function.
Status: COMPLETED
Conditions: Renal
Interventions: DRUG: avanafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)
Status: RECRUITING
Conditions: Early-stage Breast Cancer
Interventions: DRUG: Atezolizumab 1200 mg in 20 ML Injection|DRUG: Inavolisib|DRUG: Ipatasertib|DRUG: Olaparib|DRUG: Sacituzumab govitecan|DRUG: Trastuzumab/pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?
Status: RECRUITING
Conditions: Septic Shock|Hypovolemia|Sepsis
Interventions: DEVICE: End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles
Status: COMPLETED
Conditions: Metabolic Syndrome|Coronary Artery Disease|Heart Failure
Interventions: OTHER: Exercise and Cognitive testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost
Status: RECRUITING
Conditions: Primary CNS Lymphoma|Brain Lymphoma
Interventions: RADIATION: A treatment protocol of combined chemoradiation delivered in the manner of hyperfractionated conformal whole-brain radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Accuracy and Acceptability of Magnet Assisted Capsule Endoscopy in the Diagnosis of Esophageal Pathology: a Pilot Study
Status: COMPLETED
Conditions: Barrett's Oesophagus|Oesophageal Varices
Interventions: DEVICE: Magnet assissted capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IK-1001 (Sodium Sulfide (Na2S) for Injection) in Subjects With Acute ST-Segment Elevation Myocardial Infarction
Status: WITHDRAWN
Conditions: ST-Segment Elevation Myocardial Infraction
Interventions: DRUG: Sodium Sulfide (Na2S) for Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilisation in the EveNing to TreAt Delirium
Status: COMPLETED
Conditions: Critical Illness|Sleep Disturbance|Mobility Limitation|Intensive Care Unit Delirium
Interventions: OTHER: Evening mobilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early rhBNP on Myocardial Remodeling and Reperfusion in Patients With STEMI
Status: RECRUITING
Conditions: ST Segment Elevated Myocardial Infarction
Interventions: DRUG: rhBNP|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metazym for the Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
Status: COMPLETED
Conditions: Metachromatic Leukodystrophy (MLD)
Interventions: BIOLOGICAL: rhASA - Dose Level 1|BIOLOGICAL: rhASA - Dose Level 2|BIOLOGICAL: rhASA - Dose Level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet for Reduction of CNS Oxygen Toxicity in Working Divers
Status: COMPLETED
Conditions: CNS Oxygen Toxicity, Ketogenic Diet
Interventions: DIETARY_SUPPLEMENT: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Addressing Involuntary Movements in Tardive Dyskinesia
Status: COMPLETED
Conditions: Tardive Dyskinesia
Interventions: DRUG: SD-809|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHR-2004 for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
Status: RECRUITING
Conditions: Prevention of Venous Thromboembolism After Knee Arthroplasty
Interventions: DRUG: SHR-2004 injection|DRUG: SHR-2004 injection|DRUG: SHR-2004 injection|DRUG: Enoxaparin sodium injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Inhaled Bronchodilator in Non-CF Bronchiectasis With Airflow Limitation
Status: UNKNOWN
Conditions: Bronchiectasis Adult
Interventions: DRUG: LABA/LAMA or Placebo inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled Trial
Status: UNKNOWN
Conditions: Vulvodynia
Interventions: DRUG: Amitriptyline|OTHER: Kinesiotherapy|DEVICE: IC (Quark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 3- to 5-day Clinical Trial of Levamisole in Loiasis Infected Subjects
Status: NOT_YET_RECRUITING
Conditions: Loiasis
Interventions: DRUG: Levamisole 3 days|DRUG: Levamisole 5 days|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study of BIS in Hemodialysis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Failure, Chronic|Renal Failure Chronic|Hemodialysis
Interventions: DEVICE: Bioimpedance spectroscopy (BIS) measurement, SOZO device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: DRUG: AZD5363+Olaparib+Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence of Major Cardiovascular Events in Diabetic Patients With ACS Undergoing Coronary Angioplasty and Treated With Clopidogrel 150 mg Versus 75 mg
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|NSTEMI - Non-ST Segment Elevation MI|Coronary Angioplasty
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Long-Term Safety of Elexacaftor Combination Therapy
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet-rich Plasma in Subjects With Androgenetic Alopecia
Status: WITHDRAWN
Conditions: Androgenetic Alopecia
Interventions: DEVICE: Platelet Rich Plasma Prep System|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Radioisotope-guided Excision of Mediastinal Lymph Nodes in Patients With Non-small Cells Lung Carcinoma
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Sentinel lymph node scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Type of bowel resection, surgical complexity score, intraoperative blood loss, perioperative erythrocyte transfusion, type of anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Group A- Tofacitinib|DRUG: Group B- Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Contralateral Limb Training on Functional Outcomes in Patients With ACL Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Traditional rehabilitation|OTHER: Cross-over training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Discontinuation of hypertonic saline (HS)|OTHER: Continuation of hypertonic saline (HS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oesophageal Pacing to Check Left Atrial Posterior Wall Isolation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation|Atrial Fibrillation Ablation
Interventions: DEVICE: Oesophageal pacing after left atrial posterior wall isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Eszopiclone on Sleep Disturbance and Pain in Cancer
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Eszopiclone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Deep Versus Moderate Neuromuscular Block During Sevoflurane Anesthesia on Intraoperative Surgical Conditions.
Status: COMPLETED
Conditions: Surgical Conditions
Interventions: DRUG: Deep neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of FG-3019 in Adolescents and Adults With Focal Segmental Glomerulosclerosis (FSGS)
Status: TERMINATED
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DRUG: FG-3019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Establish the Feasibility of Biolen for the Local Delivery of Bicalutamide in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Lower Urinary Tract Symptoms
Interventions: COMBINATION_PRODUCT: Bicalutamide implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vektor vMap™ Clinical Validation Study
Status: COMPLETED
Conditions: Cardiac Arrhythmia|Atrial Fibrillation|Ventricular Arrythmia|Premature Ventricular Complexes Multiple|Ventricular Tachycardia|Ventricular Fibrillation|Premature Atrial Complex|Atrioventricular Reentrant Tachycardia
Interventions: DEVICE: Cardiac ablation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inflammatory Response in Laparoscopic and Open Colectomy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Laparoscopic colectomy|PROCEDURE: Open colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Meniscal Repair: A Randomized Prospective Trial of FAST-FIX vs. Meniscal Suturing
Status: COMPLETED
Conditions: Meniscal Tear
Interventions: PROCEDURE: FAST FIX|PROCEDURE: Meniscal suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Different Formulations of an Adjuvanted, Trivalent Subunit Influenza Vaccine in Elderly Subjects 65 Years of Age and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Adjuvanted, trivalent subunit influenza vaccine|BIOLOGICAL: Adjuvant level modified adjuvanted, trivalent subunit influenza vaccine|BIOLOGICAL: Antigen level modified adjuvanted, trivalent subunit influenza vaccine|BIOLOGICAL: Antigen and adjuvant level modified adjuvanted, trivalent subunit influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Frequency of Denture Cleanser Use and Denture Cleanliness
Status: COMPLETED
Conditions: Denture Cleansers
Interventions: DEVICE: Denture Cleanser Daily Use Period|DEVICE: Denture Cleanser Weekly Use Period|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Lenalidomide in Combination With Subcutaneous Rituximab + miniCHOP in DLBCL Patients of 80 y/o or+
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome
Interventions: DEVICE: Posterior Tibial Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
Status: RECRUITING
Conditions: Ventilator Associated Pneumonia|Bronchopulmonary Dysplasia|Respiratory Disease
Interventions: PROCEDURE: Standardized oral Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intralipid Therapy for Recurrent Implantation Failure and Recurrent Miscarriages: Is it a Hope or Myth?A Randomized Clinical Trial
Status: WITHDRAWN
Conditions: Pregnancy Complicated by Low Implantation
Interventions: DRUG: intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: DIAGNOSTIC_TEST: NGS-MRD|DRUG: Myeloablative allogeneic HCT with a non-TBI conditioning regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pain Neuroscience Education vs. Self-Management Education in Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: Pain Neuroscience Education|OTHER: Self-Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Reflexology and Homeopathy Added to Conventional Asthma Management
Status: COMPLETED
Conditions: Asthma
Interventions: OTHER: Reflexology plus conventional treatment|OTHER: Homeopathy plus conventional treatment|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC With Major Portal Vein Tumor Thrombosis
Status: COMPLETED
Conditions: HepatoCellular Carcinoma|Portal Vein Thrombosis
Interventions: PROCEDURE: HAIC|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients
Status: UNKNOWN
Conditions: Anaplastic Astrocytoma|Recurrent Anaplastic Astrocytoma
Interventions: DRUG: Eflornithine|DRUG: Lomustine|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TBTC Study 23: Treatment of HIV-Related Tuberculosis Using a Rifabutin-Based Regimen
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre Hospital Evaluation of Video Laryngoscopy
Status: WITHDRAWN
Conditions: Cardiac Arrest|Respiratory Distress Syndrome|Shock|Acute Post-trauma Stress State|Drug Toxicity|Trauma, Nervous System
Interventions: DEVICE: Classical intubation|DEVICE: GLIDESCOPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mood and Excess Weight Gain in Adolescent Pregnancy
Status: COMPLETED
Conditions: Obesity|Adolescent Development|Pregnancy Related|Insulin Sensitivity|Interpersonal Relations|Stress
Interventions: BEHAVIORAL: Interpersonal Psychotherapy|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Tetracycline (Doxycycline) and Post Myocardial Infarction Remodeling
Status: COMPLETED
Conditions: Myocardial Infarction|Left Ventricular Remodeling
Interventions: DRUG: Doxycycline|DRUG: Current medical therapy for AMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lycopene and Isoflavones on Glucose Metabolism
Status: WITHDRAWN
Conditions: Metabolic Syndrome|Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Randomized pills either containing combination of lycopene and isoflavones (dietary supplements) or Placebo to be taken for 12 weeks|OTHER: Screening|OTHER: OGTT|OTHER: Anthropometrics and Blood pressure|OTHER: Screening|OTHER: Blood Drawing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Non-alcoholic Beverage Based on Kombucha in Patients With Constipations
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation|Constipation-predominant Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: kombucha-based beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Transcranial Direct Current Stimulation and Gait Training in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: OTHER: Active tDCS plus gait training|OTHER: Sham tDCS plus gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Surgical Instrument in Treatment of Conlylar Fracture: Condylar Reductor
Status: COMPLETED
Conditions: Mandibular Fracture
Interventions: DEVICE: Condylar reductor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: SelG1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Vitamin D3 on Chronic Rhinosinusitis Treatment in Adults With Lower Vitamin D Levels
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Vitamin D|DRUG: Budesonide Nasal Spray|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Comparator-Controlled Study to Assess Safety and Efficacy of ISIS-FXIRx in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: ISIS-FXIRx Dose #2|DRUG: ISIS-FXIRx Dose #3|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ocular Tolerance and Intraocular Pressure (IOP) Effects of Zylet Versus Tobradex
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Loteprednol etabonate 0.5% and tobramycin 0.3%|DRUG: Dexamethasone 0.1% and tobramycin 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between The Analgesic Efficacy of Adductor Canal Block Alone and Adductor Canal With IPACK (Interspace Between Popliteal Artery and Capsule of the Knee) Block for Knee Surgeries
Status: UNKNOWN
Conditions: Nerve Blocks
Interventions: PROCEDURE: Adductor canal block and IPACK block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of BR1015 Combination Therapy
Status: RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan + Indapamide|DRUG: Fimasartan + Indapamide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage
Status: UNKNOWN
Conditions: Rectal Cancer|Rectal Neoplasms|Anastomotic Leak
Interventions: OTHER: Tube drain insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EYLEA [AMD-QOL(Age-Related Macular Degeneration-Quality of Life)] Post-marketing Surveillance in Japan
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gabapentin for Postop Pain After SSLF
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Gabapentin|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Standardized Fecal Microbiota Transplantation for Ulcerative Colitis
Status: RECRUITING
Conditions: Bacteria|Microbiota|Fecal Microbiota Transplantation|Inflammatory Bowel Disease|Ulcerative Colitis
Interventions: PROCEDURE: Standardized FMT|DRUG: Traditional treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy
Status: COMPLETED
Conditions: Muscle Weakness | Patient|Pain
Interventions: DRUG: Peripheral Nerve Block|DRUG: Sham Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Butterfly Pivotal Study
Status: RECRUITING
Conditions: BPH (Benign Prostatic Hyperplasia)|Lower Urinary Tract Symptoms (LUTS)
Interventions: DEVICE: Butterfly Prostatic Retraction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Serum and Saliva Sirtuin 6, Lipoxin A4, Caspase8 Levels in Correlation With Periodontal Status in Severe Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Diagnose Disease
Interventions: OTHER: Saliva and serum sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of NN5401 Versus Biphasic Insulin Aspart 30 on a Twice Daily Regimen in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Transglutaminase 2 as a Biomarker for Kidney Allograft Fibrosis
Status: UNKNOWN
Conditions: Kidney Allograft Fibrosis|Kidney Transplant Failure and Rejection
Interventions: DIAGNOSTIC_TEST: observational(urinary biomarker for kidney allograft fibrosis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab for Patients With PD-L1 Diffuse Large B Cell Lymphoma (DLBCL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|Lymphoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Different Formulations of an MF59-Adjuvanted Influenza Vaccine in Older Adults ≥50 Years of Age
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Experimental: IIV-A Investigational IIV-A will be administered as a single dose intramuscularly on Day 1|BIOLOGICAL: Experimental: aIIV-B Investigational aIIV-B will be administered as a single dose intramuscularly on Day 1|BIOLOGICAL: Experimental: aIIV-C Investigational aIIV-C will be administered as a single dose intramuscularly on Day 1|BIOLOGICAL: Active Comparator: Licensed IIV IIV will be administered as a single dose intramuscularly on Day 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transurethral Resection of Bladder Tumor (TURBT) Combined With Adjuvant Intravenous GC Chemotherapy for Non-muscle-invasive Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer|Gemcitabine and Cisplatin Chemotherapy|Epirubicin Instillation|Recurrence|Prognosis
Interventions: DRUG: Gemcitabine, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Very Early FDG-PET/CT-response Adapted Therapy for Advanced Hodgkin Lymphoma (H11)
Status: WITHDRAWN
Conditions: Hodgkin Lymphoma
Interventions: DRUG: ABVD + FDG-PET/CT Scan treatment adaptation|DRUG: BEACOPPesc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-week, Multicenter, proSpective stUdy to Evaluate the PASI 90 Clinical Response Rate and the Safety PRofile of sEcukinuMab 300 mg in Cw6-negativE and Cw6-positive Patients With Moderate to Severe Chronic Plaque-type Psoriasis (SUPREME)
Status: COMPLETED
Conditions: Plaque Type Psorisis
Interventions: BIOLOGICAL: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone|Nephrolithiasis
Interventions: DEVICE: INTRARENAL PRESSURE MONITORING VISIBLE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 20,000 EU of Clinical Center Reference Endotoxin in Allergic Adults With and Without Mild Asthma
Status: TERMINATED
Conditions: Mild Allergic Rhinitis|Mild Allergic Rhinitis With Mild Asthma
Interventions: BIOLOGICAL: Clinical Center Reference Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Ambu® aScope™ 4 Cysto With the aView™ 2 Advance for Flexible Cystoscopy
Status: COMPLETED
Conditions: Cystoscopy|Ureteral Stent
Interventions: DEVICE: Ambu® aScope™ 4 Cysto with the aView™ 2 Advance used for stent removal|DEVICE: Standard of care reusable cystoscope used for stent removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Sublingual Misoprostol to Reduce Primary Postpartum Haemorrhage After Vaginal Delivery
Status: UNKNOWN
Conditions: Primary Postpartum Hemorrhage|Misoprostol|Delivery Complication
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative
Status: COMPLETED
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: DRUG: Indacaterol/Glycopyrrolate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Multiple-dose Kukoamine B Mesilate in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Kukoamine B Mesilate|DRUG: placebo multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Abacavir sulfate|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: GW433908
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Therapeutic Strategy Including Nebulised Liposomal Amphotericin B (Ambisome®) in Maintenance Treatment of Allergic Bronchopulmonary Aspergillosis (Cystic Fibrosis Excluded).
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Liposomal amphotericin B (Ambisome®)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Paternal Age on Assisted Reproduction Outcome
Status: COMPLETED
Conditions: We Will Retrospectively Assess Our Databases in Our Clinic|Instituto Valenciano de Infertilidad in Valencia (Spain)|Searching for Assisted Reproduction Procedures|IUI Standard IVF/ICSI Cycles and Ovum Donation IVF/ICSI Cycles|Who Were Referred to Our Unit to Cryopreserve Sperm During the Period|From January 2000 to December 2006
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This Study Aims to Determine the Long-term Persistence of Antibodies Against Hepatitis B and to Evaluate the Immunogenicity and Safety of Hepatitis B Vaccine in Adolescents Vaccinated in Infancy With Infanrix™ Hexa
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix™-B Kinder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Positive Node Traced Before Neoadjuvant Chemotherapy (NAC)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: complete remission (CR) group|PROCEDURE: partial remission (PR) group|PROCEDURE: stable disease (SD) group|PROCEDURE: progressive disease (PD) group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of PDI-192 0.1% in Comparison to PDI-192 0.15% in the Treatment of Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: PDI-192|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glycogen Replenishment on Time Trial Performance Following a Glycogen Lowering Exercise
Status: UNKNOWN
Conditions: Carbohydrate Metabolism
Interventions: BEHAVIORAL: 20 km time trial performance|BEHAVIORAL: Glycogen lowering exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Routine Versus Selective Use of FFR to Guide PCI
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Coronary Atherosclerosis|Angina, Unstable
Interventions: DEVICE: Fractional Flow Reserve (FFR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Pharmacokinetics and Safety/Tolerability of SA001 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SA001 240mg + Rebamipide 200mg or Placebo|DRUG: SA001 480mg or Placebo|DRUG: SA001 710mg + Rebamipide 600mg or Placebo|DRUG: SA001 1,080mg or Placebo|DRUG: SA001 360mg or Placebo|DRUG: SA001 720mg or Placebo|DRUG: SA001 1,080mg or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase I Trial of Recombinant Human Interleukin-10 (SCH 52000) in Patients With Wegener's Granulomatosis
Status: COMPLETED
Conditions: Vasculitis|Wegener's Granulomatosis
Interventions: DRUG: Interleukin-10
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety of Transcranial Direct Current Stimulation in Pediatric Hemiparesis
Status: COMPLETED
Conditions: Hemiparesis
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT