pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tipifarnib and Bortezomib in Treating Patients With Acute Leukemia or Chronic Myelogenous Leukemia in Blast Phase
Status: COMPLETED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With Minimal Differentiation|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Adult Erythroleukemia|Adult Pure Erythroid Leukemia|Blastic Phase|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Disease|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Bortezomib|OTHER: Laboratory Biomarker Analysis|DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tesetaxel Plus Reduced Dose of Capecitabine vs. Capecitabine in HER2 Negative, HR Positive, LA/MBC
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Tesetaxel and Capecitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Contralateral Strength Training on Postoperative Strength Deficits in the Immobilized Lower Extremity
Status: RECRUITING
Conditions: Meniscus; Detachment, Current Injury
Interventions: OTHER: Standard of Care Rehabilitation|OTHER: Experimental Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study
Status: COMPLETED
Conditions: Copd|Smoking Cessation|Nicotine Dependence|Tobacco Use|Cigarette Smoking
Interventions: BEHAVIORAL: Unified Protocol adapted for smoking cessation|BEHAVIORAL: American Lung Association self-management strategies for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I AZD2281/Cisplatin in Advanced Solid Tumour Patients
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: AZD2281|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tag-7 Gene-modified Vaccine in Locally Advanced or Metastatic Malignant Melanoma or Kidney Cancer
Status: COMPLETED
Conditions: Melanoma|Kidney Cancer
Interventions: BIOLOGICAL: Tag-7 gene modified inactivated tumor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|SCC - Squamous Cell Carcinoma|Basal Cell Carcinoma|BCC|BCC - Basal Cell Carcinoma|Melanoma|Merkel Cell Carcinoma|Sebaceous Carcinoma|Extramammary Paget Disease|Kaposi Sarcoma|Head and Neck Squamous Cell Carcinoma|HNSCC|Adnexal Carcinoma|Angiosarcoma|Cutaneous Neoplasm|Advanced Cancer|Metastatic Cancer|Refractory Cancer|Solid Tumor
Interventions: BIOLOGICAL: MQ719|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of NeoRecormon (Epoetin Beta) in Anemic Patients With Chronic Hepatitis C.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Pegasys|DRUG: Ribavirin|DRUG: epoetin beta [NeoRecormon]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosage of Metal Ions in the Blood of Different Metal-on-metal Prostheses, in Correlation With Physical Activity
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DEVICE: metal-on-metal total hip prosthesis versus ceramic-on-ceramic total hip prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Bovine Freeze-dried Amniotic Membrane on Wound Healing in Laser Treatment
Status: COMPLETED
Conditions: Biological Dressings
Interventions: PROCEDURE: laser treatments|OTHER: amniotic membrane application|DEVICE: hydrocolloid application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Sleep Homeostasis to Improve Alcohol Use Disorder Treatment Outcomes (M-STAR Study)
Status: RECRUITING
Conditions: Insomnia|Alcohol Use Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for insomnia (CBTi)|BEHAVIORAL: Sleep Hygiene Education (SHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Intravenous Ibuprofen on Pain, Oxidative Stress and Inflammation in Laparoscopic Hysterectomy Operations
Status: COMPLETED
Conditions: Analgesia; Ibuprofen; Acetaminophen; Oxidative Stress
Interventions: DRUG: Ibuprofen 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Explore Study of Bevacizumab Combined With Conventional Therapy in Glioblastoma
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: OTHER: Chemoradiation Therapy|OTHER: Adjuvant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical AD 32 (Valrubicin) in Patients With Carcinoma in Situ (CIS) of the Bladder Who Have Failed or Have Recurrence Following Treatment With Bacillus Calmette-guerin (BCG)
Status: COMPLETED
Conditions: Carcinoma in Situ|Bladder Cancer
Interventions: DRUG: Valrubicin, 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Varenicline for 4-weeks Prior to Quitting
Status: COMPLETED
Conditions: Tobacco Dependence|Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A: Canagliflozin tablet|DRUG: Treatment A: Metformin IR tablets|DRUG: Treatment B: Canagliflozin/metformin fixed dose combination tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: Radiofrequency Ablation (RFA)|PROCEDURE: Simulated Radiofrequency Ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome
Status: COMPLETED
Conditions: High-Frequency Microsatellite Instability|Mismatch Repair Gene Mutation|Mutation-Negative Lynch Syndrome|Mutation-Positive Lynch Syndrome
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Informational Intervention|DEVICE: Monitoring Device|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EVALUATION OF EFFICACY OF SAMEUP IN SUBJECTS WITH DEPRESSION SYMPTOMS: A RANDOMIZED STUDY
Status: COMPLETED
Conditions: Depressive Symptoms
Interventions: COMBINATION_PRODUCT: SAMEUp|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Intravesical Electromotive Mitomycin-c for Primary Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Superficial Bladder Cancer
Interventions: DRUG: Mitomycin-C 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: OPAM-IA: Using Digital Activity Trackers to Improve Physical Activity in Inflammatory Arthritis
Status: COMPLETED
Conditions: Joint Diseases|Rheumatoid Arthritis|Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Education, Fitbit/FitViz, physiotherapist counselling.|BEHAVIORAL: Same intervention with a 9-week delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MED90 of Ropivacaine for Peripheral Nerve Block on Posture-evoked Pain in Spinal Anesthesia Positioning
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: PROCEDURE: Fascia iliaca block|PROCEDURE: Femoral nerve block|PROCEDURE: Pericapsular nerve group block (PENG block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 425809|DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descartes-08 for Patients With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: Descartes-08
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Control for Glucocorticoid Induced Hyperglycemia During Chemotherapy
Status: COMPLETED
Conditions: Hyperglycemia Steroid-induced
Interventions: DRUG: Sliding scale insulin|DRUG: Intermediate acting insulin|BEHAVIORAL: Dietary advice|DRUG: Glucose lowering medication|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Thoracoscopic Intraoperative Lung Ultrasound to Identify Pulmonary Metastases in Patients Submitted to Pulmonary Metastasectomy With Radical Intent.
Status: UNKNOWN
Conditions: Pulmonary Metastases
Interventions: DIAGNOSTIC_TEST: Intraoperative intracavitary lung ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transarterial Ethanol Ablation (TEA) Versus Transcatheter Arterial Chemoembolisation (TACE) for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TEA with LEM|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Continuous Intra-airway Monitoring Under Visible Double-lumen Bronchial Catheter on Postoperative Complications of Lung Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pulmonary Complications
Interventions: PROCEDURE: Continuous intra-airway monitoring and intervention during surgey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Booster Immunization Study of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)
Status: COMPLETED
Conditions: COVID19
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Fusion Protein Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bronchoscopic Cryo-Immunotherapy of Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DEVICE: ERBOKRYO® CA - Cryosurgical Unit with Flexible ERBECRYO Probe, 1.9 mm outer diameter (ERBE Inc., Tubingen, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy and Safety of Perampanel Added to Monotherapy in Participants With Partial Onset Seizures With or Without Secondary Generalization
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Manipulation + Exercise Group|PROCEDURE: Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Platinum Sensitive Ovarian Cancer
Interventions: DRUG: Active comparator: Niraparib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Calming Effect of Vanilla Odor on Preterm Infant Without Mother's Breast Milk Feeding
Status: TERMINATED
Conditions: Preterm Infant
Interventions: BIOLOGICAL: Venipuncture|DEVICE: Diffuser spreading odor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Postoperative Telemedicine Visit vs In-person Visit on Patient Satisfaction During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Covid19|Satisfaction, Patient|Telemedicine
Interventions: BEHAVIORAL: Telemedicine visit|BEHAVIORAL: In-person postoperative visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of CNSI vs. ICG in Lymph Node Tracing During Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: carbon nanoparticles|DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: DS-5670a|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison Between Surgical Techniques for Securing Conjunctival Autografting in Primary Pterygium Surgery
Status: UNKNOWN
Conditions: Pterygium
Interventions: PROCEDURE: conjunctival autograft with fibrin glue|PROCEDURE: sutured conjunctival autograft|PROCEDURE: sutureless and glue-free conjunctival autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study for Treatment With Calcipotriol/Betamethasone Dipropionate Gel in Korean Patients With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriol/betamethasone dipropionate gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of 200 mg Versus 400mg Vaginal Progesterone in Prevention of Preterm Labor in Twin Gestation
Status: UNKNOWN
Conditions: Twin; Pregnancy, Affecting Fetus or Newborn
Interventions: DRUG: progesterone 400mg|DRUG: progesterone 200mg|DRUG: placebo to progesterone 200mg|DRUG: placebo to progesterone 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgery With Extended (D3) Mesenterectomy for Small Bowel Tumors
Status: RECRUITING
Conditions: Small Bowel Cancer|Small Bowel Carcinoid Tumor|Quality of Life|Lymph Node Metastases|Tumor Metastasis
Interventions: PROCEDURE: Surgery with extended (D3) mesenterectomy for small bowel tumors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Scalable, IVR-supported Cancer Prevention Interventions in the Rural Alabama Black Belt
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity
Interventions: BEHAVIORAL: Deep south Interactive voice response system supported Active Lifestyle (DIAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
Status: NOT_YET_RECRUITING
Conditions: Incontinence|Erectile Dysfunction Following Radical Prostatectomy
Interventions: OTHER: Patient Education|OTHER: Pelvic Floor Muscle Training|OTHER: Aerobic Exercise Training|OTHER: Resistance Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once-Weekly Oral Aminopterin for the Treatment of Subjects With Moderate-To-Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: LD-Aminopterin oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transforming Nanoparticle Dressing For Management of Chronic Venous Ulcers
Status: COMPLETED
Conditions: Chronic Venous Hypertension With Ulcer
Interventions: COMBINATION_PRODUCT: Transforming nanoparticle dressing|COMBINATION_PRODUCT: Conventional compression dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relevance Study Between the Result of Clinical Drug Intervention and Next-generation Sequencing Technology Focused on Refractory Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Gastritis
Interventions: DEVICE: The eradication times of the patients|DEVICE: The result of 13C-urea breath test after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ibuprofen on Post-partum Blood Pressure in Women With Hypertensive Disorders of Pregnancy
Status: COMPLETED
Conditions: Hypertension, Pregnancy-Induced|Pre-eclampsia
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Music Therapy in Improving the Physical Fitness and Depression in the Frailty of the Community Elderly
Status: COMPLETED
Conditions: Music Therapy|Frailty|Physical Fitness|Depression
Interventions: OTHER: music therapy activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pulse Fractions on Indices on Cardiovascular Disease and Diabetes Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: Whole yellow pea flour|OTHER: Fractionated pea flour|OTHER: White wheat flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Percutaneous Electric Neurostimulation of Dermatome T7 Improves Glycemic Profile in Obese and Typo 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2 in Obese|Type 2 Diabetes Mellitus With Features of Insulin Resistance
Interventions: DEVICE: Percutaneous Neurostimulation (PENS) of dermatome T7|OTHER: 1200 Kcal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aortic Valve Dynamics During Exercise After Valve Sparing Root Replacement Surgery
Status: COMPLETED
Conditions: Aneurysm Aortic Root|Aortic Valve, Bicuspid
Interventions: DIAGNOSTIC_TEST: graded bicycle test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study
Status: TERMINATED
Conditions: Failed Moderate Sedation During Procedure|Ketamine Adverse Reaction
Interventions: DRUG: Ketamine Hcl 100Mg/Ml Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure
Status: RECRUITING
Conditions: Intervertebral Disc Degeneration|Stenosis, Spinal|Spondylolisthesis|Spinal Deformity|Spinal Instability
Interventions: DIAGNOSTIC_TEST: Somatosensory evoked potential [SSEP] intraoperative monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cervical Vestibular Evoked Myogenic Potentials in Recurrent and Persistant Benign Paroxysmal Positional Vertigo
Status: RECRUITING
Conditions: Benign Paroxysmal Positional Vertigo
Interventions: DEVICE: Cervical VEMP testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: visugromab (CTL-002)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel+Reparixin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCRT Followed by Tegafur, Gimeracil and Oteracil Potassium in Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Chemotherapy
Interventions: DRUG: Tegafur, Gimeracil and Oteracil Potassium Capsules (one drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Adapted Physical Activity for Patients Suffering From Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: BEHAVIORAL: Adapted Physical Activity (APA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Pecan Nut Snacks v Equicaloric Snacks on Appetite, Food Intake, Metabolism, Hormones and Biomarkers
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: OTHER: Pecan snack|OTHER: Tortilla chip snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Animal Assisted Therapy in Outpatient Psychiatry Clinics
Status: TERMINATED
Conditions: Anxiety|Depression|Psychiatric or Mood Diseases or Conditions
Interventions: OTHER: Animal assisted therapy cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DRUG: Sodium Picosulphate|DRUG: Polyethylene Glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mother-caregivers of Children With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Other Diseases or Conditions
Interventions: BIOLOGICAL: sleep parameters|BIOLOGICAL: Hormonal profile|BIOLOGICAL: Inflammatory profile|BIOLOGICAL: Cardiovascular profile|BIOLOGICAL: Metabolic profile
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: The Effects of the Telomerase Activator TA-65 on Insulin Resistance, Inflammation, and Metabolic Syndrome
Status: TERMINATED
Conditions: Metabolic Syndrome|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: TA-65|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cefdinir for Oral Suspension 250 mg/5mL, Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefdinir for oral suspension 250 mg/5mL|DRUG: OMNICEF® for oral suspension 250 mg/5mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial to Study the Efficacy and Safety of Different Doses of Bone Marrow Derived Mesenchymal Stem Cells in Patients With Critical Limb Ischemia Due to Buergers Disease
Status: COMPLETED
Conditions: Critical Limb Ischemia|Buerger's Disease
Interventions: BIOLOGICAL: Allogeneic Mesenchymal Stem Cells|BIOLOGICAL: Allogeneic Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Autoregulation and COVID-19
Status: RECRUITING
Conditions: COVID-19 Acute Respiratory Distress Syndrome|COVID-19 Pneumonia
Interventions: OTHER: NIRS (Near-Infrared Spectroscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Adalimumab Combined to Chemotherapy and Radiotherapy in Patients With Anaplastic Thyroid Cancers
Status: WITHDRAWN
Conditions: Anaplastic Thyroid Cancers
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil 250 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Mycophenolate Mofetil|DRUG: CellCept®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Randomized Trial of Ipilimumab Versus Ipilimumab and Radiotherapy in Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Ipilimumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
Status: RECRUITING
Conditions: Unresectable Melanoma|Metastatic Melanoma|Stage III Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: IOV-4001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation or Radical Treatment in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: conventional surgery|RADIATION: brachytherapy|RADIATION: external beam radiation therapy|PROCEDURE: Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAMP1: The 1T1T Concept Versus Conventional Implant Loading Protocol
Status: UNKNOWN
Conditions: Dental Implant Failure|Dental Prosthesis Failure
Interventions: PROCEDURE: The 1T1T concept versus conventional implant loading protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BN83495 in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: BN83495 (Cohort 1)|DRUG: BN83495 (Cohort 2)|DRUG: BN83495 (Cohort 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Management of Dialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis|Life Quality|Interdialytic Weight Gain|Cardiovascular Events|Hypertension|Dry Weight
Interventions: OTHER: Family weight self-measurement and remote follow-up management based on wechat.|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT of a Web-based Intervention to Improve Quality of Life in Late Stage Bipolar Disorder (ORBIT)
Status: COMPLETED
Conditions: Bipolar Disorder, Currently in Remission
Interventions: BEHAVIORAL: Mindfulness for Bipolar|BEHAVIORAL: Psychoeducation for Bipolar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparision of Different Doses of Dexmedetomidine With Low Dose Bupivacaine in Selective Spinal Anesthesia.
Status: UNKNOWN
Conditions: Drug Effect
Interventions: DRUG: Dexmedetomidine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Early TIPS (Transjugular Intrahepatic Portosystemic Shunts) in the Management of Cirrhosis With Recurrent Ascites.
Status: UNKNOWN
Conditions: Liver Cirrhoses
Interventions: PROCEDURE: Transjugular Intrahepatic Portosystemic Shunt|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: paclitaxel|DRUG: triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Origin of Premature Atrial Beats Induced by Simulated Obstructive Sleep Apnea
Status: TERMINATED
Conditions: Atrial Fibrillation|Sleep Apnea, Obstructive|Atrial Premature Complexes
Interventions: PROCEDURE: Standard pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: TRC105 in Adults With Advanced/Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma|Ureteral Neoplasms|Ureter Cancer|Neoplasm, Ureteral|Cancer of the Ureter
Interventions: DRUG: TRC105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA
Status: UNKNOWN
Conditions: Malfunction; Catheter|Thrombosis|Mechanical Complication of Hemodialysis Catheter
Interventions: DRUG: rt-PA (2mg/2mL) actilysis|DRUG: rt-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Call for Life Youth ART Adherence Study
Status: COMPLETED
Conditions: ART Adherence|HIV-1-infection|mHealth
Interventions: OTHER: mHealth call for life system/ tool using IVR ( interactive voice response)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus
Status: TERMINATED
Conditions: Patent Ductus Arteriosus|Preterm Infant|Bronchopulmonary Dysplasia
Interventions: DRUG: Ibuprofen and acetaminophen|DRUG: Ibuprofen and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NeuroTrainer Cognitive Training For Academic Focus
Status: NOT_YET_RECRUITING
Conditions: ADHD - Combined Type|ADHD Predominantly Inattentive Type|ADHD, Predominantly Hyperactive - Impulsive
Interventions: BEHAVIORAL: NeuroTrainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Comparing the Effect of Different Dosing Conditions on Blood Levels of Semaglutide in a New Tablet Composition in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy and QS21 in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: QS21|BIOLOGICAL: sialyl Lewisª-keyhole limpet hemocyanin conjugate vaccine|OTHER: immunoenzyme technique|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelets Antiaggregation Control Enhancement (PACE) Study
Status: TERMINATED
Conditions: Bleeding|Blood Transfusion
Interventions: DEVICE: Aggregometry+Thromboelastography|DEVICE: Thromboelastography Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ixazomib-pomalidomide-dexamethasone as Second or Third-line Combination Treatment for Patients With Relapsed and Refractory Multiple Myeloma Previously Treated With Daratumumab, Lenalidomide and Bortezomib
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma in Relapse|Refractory Multiple Myeloma
Interventions: DRUG: ixazomib-pomalidomide-dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and / or Deficiencies in Adult Population
Status: RECRUITING
Conditions: Motor Disorders|Gait Disorders, Neurologic|Neurodegenerative Diseases|Spinal Cord Injuries|Weakness, Muscle|Cerebrovascular Accident
Interventions: DEVICE: Hands-free exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Canadian Underage Substance Use Prevention Trial
Status: UNKNOWN
Conditions: Substance Use Disorders|Adolescent Behavior|Adolescent Development
Interventions: BEHAVIORAL: PreVenture Training (PTtT)|BEHAVIORAL: PreVenture Training+Implementation Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bone Marrow Mesenchymal Stem Cells Transfer in Patients With ST-segment Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: BIOLOGICAL: Bone marrow mesenchymal stem cells transfer|DRUG: Best medical treatment|PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study for Determine the Safety and Efficacy of Clostridium Botulinum Toxin Type A in Subjects With Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: MT10109|BIOLOGICAL: BOTOX(Registered trade mark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Neoplasm|Advanced Melanoma|Advanced Renal Cell Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIA Ovarian Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIA1 Ovarian Cancer AJCC v8|Stage IIIA2 Ovarian Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIB Ovarian Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IIIC Ovarian Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MEDITOXIN® in Treatment of Crow's Feet Line
Status: COMPLETED
Conditions: Crow's Feet Lines
Interventions: DRUG: botulinum toxin type A|DRUG: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Effectiveness of the Renew Insert in Treating Accidental Bowel Leakage
Status: COMPLETED
Conditions: Bowel Incontinence
Interventions: DEVICE: Renew Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MP-424, Peginterferon Alfa-2b and Ribavirin in Chronic Hepatitis C Who Have Not Achieved an Undetectable HCV RNA Level With Previous Interferon Based Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: MP-424|DRUG: Ribavirin|DRUG: Peginterferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Music on Post-operative Pain and Anxiety
Status: UNKNOWN
Conditions: Closed Fracture of Shaft of Femur|Postoperative Pain|Postoperative Anxiety
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Face to Face Versus a Remote Physiotherapy Instruction Session About Pelvic Floor in Women With Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence
Interventions: OTHER: Face to face intervention group|OTHER: Remote intervention group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: SC-PEG|DRUG: Oncaspar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fish Oil on Insulin Sensitivity
Status: COMPLETED
Conditions: Metabolic Syndrome X|Type 2 Diabetes Mellitus|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: EPAX 6000 (marine omega 3 EPA/DHA fatty acid concentrates|DIETARY_SUPPLEMENT: Maize (corn) oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Acute Nicotine Treatment on Neuroplasticity and Memory in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Nicotine polacrilex|DRUG: Regular chewing gum; Dentyne Ice, Wrigely´s Mint Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin
Status: TERMINATED
Conditions: Critical Limb Ischemia (CLI)
Interventions: DRUG: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Reality Simulation Environment on the Skills of Midwifery Students, in Newborn Heel Blood Collection
Status: COMPLETED
Conditions: Students|Educational Problems|Anxiety
Interventions: BEHAVIORAL: Heel blood collection in a newborn simulation model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Myofascial Release at the Cervicothoracic Region in Patients With Rotator Cuff Repairs
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: OTHER: myofascial release technique|OTHER: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Discontinuing Dornase Alfa in People With CF on Highly Effective CFTR Modulator Therapy-A SIMPLIFY Sub-Study
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Discontinuation of dornase alfa (Dnase)|OTHER: Continuation of dornase alfa (Dnase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interventional X-ray and Scintigraphy Imaging of 99mTc-MAA During the Radioembolisation Pretreatment Procedure
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DEVICE: IXSI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19 Illness (Long-COVID)
Status: COMPLETED
Conditions: Covid19|Sequelae of; Infection|Cognitive Symptom
Interventions: DRUG: Niagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Breast Milk Circadian Properties on Infant's Growth Parameters and Absorption of Nutrients
Status: RECRUITING
Conditions: Breast Feeding|Breast Milk Collection
Interventions: OTHER: Giving breast milk to the newborn according to the circadian rhythm|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zileuton to Treat Adults With Chronic Obstructive Pulmonary Disease (The LEUKO Study)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Zileuton|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Efficacy Study of the Stendo Pulsating Suit in Patient With Leg Lymphoedema
Status: COMPLETED
Conditions: Primary Lower Limb Lymphedema|Secondary Lower Limb Lymphedema
Interventions: OTHER: Current intensive CDP|OTHER: intensive CDP where Stendo pulsating suit replaces pressotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT