pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Investigational aQIVc|BIOLOGICAL: licensed QIV1|BIOLOGICAL: licensed QIV2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Development of a Novel Polyherbal Lip Hydrant for Improving Biophysical Barrier of the Lips
Status: COMPLETED
Conditions: Cheilitis
Interventions: OTHER: Lip hydrant|OTHER: Petroleum gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Hypoxia Therapy in Cardiac Rehabilitation
Status: COMPLETED
Conditions: Cardiovascular Disease|Exercise|Hypoxia
Interventions: DEVICE: Intermittent hypoxia therapy|OTHER: Conventional phase 2 cardiac rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Age 6 Test of Home Visits by Nurses vs Paraprofessionals
Status: COMPLETED
Conditions: Child Rearing|Risk Reduction Behavior|Reproductive Behavior
Interventions: BEHAVIORAL: home visitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia
Status: TERMINATED
Conditions: Dementia, Vascular|Dementia, Mixed
Interventions: DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy
Status: RECRUITING
Conditions: Inferior Alveolar Nerve Injury|Nerve Injury|Neurosensory Disorder|Mandibular Nerve Injury
Interventions: PROCEDURE: Platelet-rich fibrin (PRF)|PROCEDURE: Proximal segment grooving (PSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ANTIcoagulation in Severe COVID-19 Patients
Status: COMPLETED
Conditions: Severe COVID-19 Pneumonia
Interventions: DRUG: Tinzaparin, Low dose prophylactic anticoagulation|DRUG: Tinzaparin, High dose prophylactic anticoagulation|DRUG: Tinzaparin,Therapeutic anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-adhesive Liquid Embolic System in the Embolization of Cerebral Arteriovenous Malformations
Status: RECRUITING
Conditions: Intracranial Arteriovenous Malformations
Interventions: DEVICE: embolism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explore Transplant at Home: Improving Low-Income ESRD Patients' Transplant Knowledge
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: OTHER: Patient-Guided|OTHER: Educator-Guided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Myocardial Ischaemia After Exposure to Diesel Exhaust
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: OTHER: CT/PET Myocardial Perfusion Imaging using O-15 water|OTHER: Coronary blood flow measured by doppler echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smartphone-delivered Automated Video-assisted Smoking Treatment for People Living With HIV
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Self-help materials|DRUG: nicotine patch|BEHAVIORAL: Counseling|OTHER: Smartphone-delivered automated treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Dose Intravenous Vitamin C in Severe Pneumonia
Status: RECRUITING
Conditions: Pneumonia
Interventions: DRUG: Active Ingredient|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Osteoarthritis With the Stromal Vascular Fraction of Abdominal Adipose Tissue - a Pilot Study
Status: COMPLETED
Conditions: Osteoarthritis|Stem Cells
Interventions: BIOLOGICAL: injection with the stromal vascular fraction (SVF) of adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Major Depressive Disorder With MK0869 (0869-060)(COMPLETED)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: aprepitant|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Reproductive Function in Women With Polycystic Ovary Syndrome by High Intensity Interval Training
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: 4x4 minutes high intensity interval training|BEHAVIORAL: 10x1 minute high intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
Status: RECRUITING
Conditions: Hearing Loss|Dementia|Cognitive Impairment
Interventions: DEVICE: HEARS-SLP device|BEHAVIORAL: HEARS-SLP program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Whey Protein and Its Hydrolysate on Pre- and Post-Fixed Meal Glycemia and Insulin in Young Adults
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: dietary intervention|OTHER: water control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 18F-rhPSMA-7.3 PET/MRI in Prostate Cancer Active Surveillance: A Pilot Study
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 18F-rhPSMA-7.3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Comparative Bioavailability Study of 6Mercaptopurine (Delayed Release vs. Purinethol) in Crohns Disease Patients
Status: COMPLETED
Conditions: Crohns Disease
Interventions: DRUG: Delayed Release 6 mercaptopurine|DRUG: 6 Mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Prefrontal Transcranial Random Noise Stimulation in Patients With Depression
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: Verum Prefrontal tRNS|DEVICE: Placebo Prefrontal tRNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy for Intraoperative Blood Pressure Control
Status: NOT_YET_RECRUITING
Conditions: Nasal Polyps|Anesthesia|Sinusitis|ENT Surgical Result - Nose Nasal Congestion
Interventions: DEVICE: auricolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment
Status: COMPLETED
Conditions: Childhood Central Nervous System Germ Cell Tumor|Childhood Extragonadal Germ Cell Tumor|Childhood Hepatoblastoma|Childhood Hepatocellular Carcinoma|Childhood High-grade Cerebral Astrocytoma|Childhood Low-grade Cerebral Astrocytoma|Childhood Malignant Ovarian Germ Cell Tumor|Childhood Malignant Testicular Germ Cell Tumor|Childhood Teratoma|Recurrent Adrenocortical Carcinoma|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Cerebellar Astrocytoma|Recurrent Childhood Cerebral Astrocytoma|Recurrent Childhood Ependymoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Childhood Visual Pathway and Hypothalamic Glioma|Recurrent Colon Cancer|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Nasopharyngeal Cancer|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Rectal Cancer|Recurrent Renal Cell Cancer
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 18F-FES PET on the Therapeutic Treatment of Patients With Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: 18F Fluoroestradiol Radiopharmaceutical with PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Investigate the Cumulative Live Birth Rates Using GnRH Antagonist or Agonist Protocol for COS in ART Treatment
Status: UNKNOWN
Conditions: Sterility
Interventions: PROCEDURE: GnRH-ant protocol|PROCEDURE: GnRH-a long protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nomogram to Predict Breast Cancer Related Lymphedema
Status: RECRUITING
Conditions: Breast Cancer|Axillary Lymph Node Dissection|Breast Cancer Related Lymphedema|Axillary Reverse Mapping
Interventions: PROCEDURE: Axillary surgery based on lymphedema prediction nomogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Ragweed (Ambrosia Artemisiifolia) Allergy Immunotherapy Tablet in Adults With Ragweed Allergies (P05751)
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: SCH 39641|DRUG: Placebo for SCH 39641
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leuprorelin Acetate DPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty
Status: COMPLETED
Conditions: Central Precocious Puberty
Interventions: DRUG: Leuplin DPS 11.25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Circulating Liposomal Prednisolone Versus Pulse Intramuscular Methylprednisolone in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: long-circulating liposomal prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neuronal Mechanisms of Sensory Processing During General Anesthesia
Status: UNKNOWN
Conditions: General Anesthesia
Interventions: DRUG: Sevoflurane|DRUG: Isoflurane|DRUG: Desflurane|DRUG: Propofol|DRUG: Fentanyl|DRUG: Sufentanil|DRUG: Alfentanil|DRUG: Remifentanil|DEVICE: Midlatency auditory evoked potentials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts
Status: COMPLETED
Conditions: Condylomata Acuminata
Interventions: DRUG: Polyphenon E Ointment 10%, Polyphenon E Ointment 15%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Thoracolumbar Burstfractures, Orthesis or No Orthesis
Status: UNKNOWN
Conditions: Spinal Fractures
Interventions: DEVICE: Orthesis|BEHAVIORAL: No orthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project N-Liten- HIV Prevention for African American Women
Status: COMPLETED
Conditions: Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Horizons+General Health Promotion (GHP)|BEHAVIORAL: Horizons+Motivational Enhancement Therapy (GMET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Entecavir for Patients With Decompensated Hepatitis B Virus (HBV)-Related Cirrhosis
Status: UNKNOWN
Conditions: Hepatitis B Virus|Decompensated Cirrhosis
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Dose Escalation in Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention of Diet Registration Method for Rehabilitation Patients
Status: COMPLETED
Conditions: Digital Clinical Diet Registrations Advantages|Patients in Rehabilitation
Interventions: OTHER: Digital dietary registration|OTHER: Conventional dietary registration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Course Radiation Therapy in Palliative Treatment of Complicated Bone Metastases
Status: UNKNOWN
Conditions: Bone Metastases|Radiotherapy|Palliative Care
Interventions: RADIATION: standard treatment|RADIATION: short course treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant in Treating Patients With Myeloid Cancer or Other Disease
Status: TERMINATED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: fludarabine phosphate|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Intravenous Dexketoprofen and Paracetamol in the Treatment of Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: paracetamol|DRUG: Dexketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HPV Vaccine Confident Families
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus Vaccines
Interventions: BEHAVIORAL: Tailored messages|BEHAVIORAL: Standard messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL)
Status: WITHDRAWN
Conditions: Peripheral T-Cell Lymphoma (PTCL NOS)|Nodal Lymphomas of T Follicular Helper (TFH)|Follicular T-cell Lymphoma (FTCL)|AITL|ALCL|HSTCL|EATL I,II|MEITL, EATL Type II|Nasal Lymphoma
Interventions: DRUG: Cerdulatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study of Melphalan HCL & Alkeran for Injection of MA Conditioning in MM Patients of Autologous Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan HCL for Injection (Propylene Glycol-Free)/Alkeran for Injection|DRUG: Alkeran for Injection/Melphalan HCL for Injection (Propylene Glycol-Free)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment
Status: COMPLETED
Conditions: Photoaging
Interventions: DEVICE: CLEAR + BRILLIANT TOUCH(R) 1440-nm and 1927-nm handpieces.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Status: UNKNOWN
Conditions: Sedentary Behavior|Light Intensity Physical Activity
Interventions: BEHAVIORAL: Sitting interrupted by light physical activity|BEHAVIORAL: Sitting with cognitive task|BEHAVIORAL: uninterrupted sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Accuracy of Spybite Forceps When Compared to Conventional Sampling Methods
Status: COMPLETED
Conditions: Accuracy of Tissue Diagnosis|Bile Duct Stricture|Pancreatic Duct Stricture
Interventions: PROCEDURE: ERCP with cholangiopancreatoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparision Between Activated Partial Thromboplastin Time Versus Anti-Xa Activity in Heparin Monitoring
Status: UNKNOWN
Conditions: Myocardial Infarction|Venous Thromboembolism|Stroke|Bleeding
Interventions: DRUG: Unfractionated heparin|DRUG: Unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flow Diversion in Intracranial Aneurysm Treatment
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: PROCEDURE: flow diversion|OTHER: conservative management|PROCEDURE: endovascular coiling|PROCEDURE: balloon parent vessel occlusion|PROCEDURE: surgical clipping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Age Bias on Biopsychosocial Factors in Persons With Non-specific Low Back Pain.
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Symptom Modulation Approach, Movement Control Approach, Functional Optimization Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Potential Impact of Patient Vitamin D Status in AK Response to MAL-PDT
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: OTHER: Conventional MAL-PDT|OTHER: Calcipotriol assisted MAL-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Anxiety Control During Traditional Mandibular Anesthesia in Children Using Distracting Tools
Status: COMPLETED
Conditions: Inferior Alveolar Nerve Block
Interventions: PROCEDURE: VR Box|PROCEDURE: Tablet Device|DRUG: Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Adaptation of the Dose of Iron Supplementation in Pregnancy on Maternal-child Health. (ECLIPSES)
Status: COMPLETED
Conditions: Anemia Ferropenic|Risk of Hemoconcentration (Iron Levels >130g/L)
Interventions: DRUG: 40mg/day of iron|DRUG: 20mg/day of iron|DRUG: 80mg/day of iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Carcinoma|Colorectal Carcinoma|Lung Carcinoma|Malignant Solid Neoplasm|Ovarian Carcinoma|Pancreatic Carcinoma|Prostate Carcinoma
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Educational Intervention|PROCEDURE: Genomic Profile|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Spirulina Supplementation and Infant Growth, Morbidity and Motor Development
Status: COMPLETED
Conditions: Stunting|Underweight|Pneumonia, Pneumocystis|Cough|Malaria|Fever|Motor Delay
Interventions: DIETARY_SUPPLEMENT: Spirulina|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TARGIT-C(Consolidation) Prospective Phase IV Study of IORT in Patients With Small Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Intraoperative radiotherapy (IORT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cipro Inhale in Patients With Non-cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Ciprofloxacin (Cipro, BAYQ3939)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective Effect of Remote Ischemic Conditioning in Ischemic Stroke Treated With Mechanical Thrombectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Ischemic
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Patients with a sham procedure of remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
Status: RECRUITING
Conditions: Spinal Cord Injuries|Healthy
Interventions: OTHER: Downhill Eccentric Treadmill Training with Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Insulin for Postoperative Wound Healing
Status: ACTIVE_NOT_RECRUITING
Conditions: Wound Complication|Insulin Resistance, Diabetes
Interventions: DRUG: Insulin|DRUG: Povidone-Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cervical CIN II/III Treatment Outcomes With Thermal Ablation Device
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DEVICE: Standard C02 Cryotherapy|DEVICE: Single Tip Thermoablation|DEVICE: Multiple Tip Thermoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rectal Bacteriotherapy, Fecal Microbiota Transplantation or Oral Vancomycin Treatment of Recurrent Clostridium Difficile Infections
Status: UNKNOWN
Conditions: Clostridium Difficile
Interventions: DRUG: Vancomycin|DRUG: Fecal microbiota transplantation|DRUG: Rectal bacteriotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DNA Analysis in Influencing Response to Rituximab in Samples From Patients With Follicular Lymphoma Treated on ECOG-E4402
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|GENETIC: DNA analysis|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Amyloidosis Cardiac|Carpal Tunnel Syndrome
Interventions: DIAGNOSTIC_TEST: DPD Scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PREventing CHemotherapy Induced Neuropathy (PreChIN)
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy (CIPN)
Interventions: DEVICE: Hypothermia|DEVICE: Cryocompression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Touch and Feel Evaluation of Two Foam Hand Sanitizers
Status: COMPLETED
Conditions: Hand Hygiene
Interventions: DRUG: Post-market foam alcohol-based hand sanitizer #1|DRUG: Post-market foam alcohol-based hand sanitizer #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Children's Compliance With Toothbrushing Using Manual U-shaped Toothbrush Versus Regular Toothbrush
Status: NOT_YET_RECRUITING
Conditions: Manual Toothbrush
Interventions: DEVICE: manual u-shaped toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: NEO-PV-01|BIOLOGICAL: Nivolumab|OTHER: Adjuvant|BIOLOGICAL: APX005M|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Eating Education for Latinos
Status: COMPLETED
Conditions: Diet, Healthy|Diet Habit|Obesity|Blood Pressure|Psychological
Interventions: BEHAVIORAL: Culturally tailored healthy eating advice|BEHAVIORAL: Standard healthy eating advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of the Consumption of a Supplement Rich in Docosahexaenoic Acid (DHA) From Algae
Status: COMPLETED
Conditions: Vegetarian Diet
Interventions: DIETARY_SUPPLEMENT: Dietary supplement, DHA or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor
Status: COMPLETED
Conditions: Essential Head Tremor
Interventions: DRUG: BOTOX ® 200 Unités|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pasireotide Long Acting Release (LAR) Injection in Patients With Acromegaly and Patients With Carcinoid Disease
Status: COMPLETED
Conditions: Carcinoid Tumor|Acromegaly
Interventions: DRUG: Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control
Status: RECRUITING
Conditions: Myopia, Progressive
Interventions: DEVICE: Double Helix Design Defocus Lens Spectacle (RACE)|DEVICE: single-vision spetacle lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DEVICE: Sedline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection
Status: UNKNOWN
Conditions: Acute Lower Respiratory Tract Infection|Pneumonia|Bronchiolitis
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus VIC-1911 in Lenvatinib-unresponsive or Lenvatinib-resistant HCC
Status: RECRUITING
Conditions: Liver Cancer|Hepatocellular Carcinoma|Resistant Cancer
Interventions: DRUG: Lenvatinib Oral Product Plus VIC1911
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety Between Levocetirizine and Loratadine for Chronic Idiopathic Urticaria
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: levocetirizine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Fecal Microbiota Transplant (FMT) oral capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performances of 3-different Tooth-colored Restorative Materials in Class-II Cavities
Status: ACTIVE_NOT_RECRUITING
Conditions: Caries,Dental
Interventions: DEVICE: Cention N (Ivoclar Vivadent, Schaan, Liechtenstein)|DEVICE: Equia Forte HT ( GC, Tokyo, Japan)|DEVICE: Gradia Direct Posterior ( GC, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen Membrane
Status: COMPLETED
Conditions: Furcation Defects
Interventions: PROCEDURE: Open flap surgery|DEVICE: Bio-oss collagen|DEVICE: Bio-gide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of LY3462817 and LY3509754 in Participants With Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: LY3462817 - IV|DRUG: LY3462817 - SC|DRUG: Placebo - IV|DRUG: Placebo - SC|DRUG: LY3509754|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)
Status: COMPLETED
Conditions: Alcohol Abstinence
Interventions: DRUG: Guanfacine XR 3mgs/daily|DRUG: Placebo (for guanfacine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV; part2
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: reflectory breathing therapy|PROCEDURE: conventional breathing therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer
Status: UNKNOWN
Conditions: Asthma
Interventions: DEVICE: oxyhydrogen|DEVICE: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transplant Patients
Status: UNKNOWN
Conditions: HIV-1-infection|Solid Organ Transplant
Interventions: DRUG: Lamivudine 300 MG|DRUG: Abacavir 600 MG|DRUG: Dolutegravir 50 mg|DRUG: Tenofovir Disoproxil 245Mg Tablet|DRUG: Emtricitabine 200 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection
Status: COMPLETED
Conditions: Spinal Stenosis|Lumbosacral Spondylosis|Radiculopathy
Interventions: DRUG: Triamcinolone Acetonide and normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 12 Lead ECG Telemetry on Reperfusion Time in Resource-limited Settings
Status: COMPLETED
Conditions: Myocardial Infarction|STEMI
Interventions: OTHER: Telemetry|OTHER: Non-telemetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA5 Device
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke From Large Vessel Occlusion
Interventions: DEVICE: ANA Funnel Catheter|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Mind-Body Breathing Therapy (in Chronic Obstructive Pulmonary Disease) To Improve Palliation of Dyspnea and Health-Related Quality of Life
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Relaxation Response (instruction, pocket practice card prov)|BEHAVIORAL: Mindfulness training using model developed from UMass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pneumoperitoneum and Steep Trendelenburg on Autonomic Nervous System
Status: COMPLETED
Conditions: Autonomic Nervous System
Interventions: PROCEDURE: pneumoperitoneum insufflation and steep trendelenburg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open Label Study Etanercept's Maintenance Dose in Obese Patients With Moderate to Severe Plaque Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: PROCEDURE: Narrow band (310-312 nm) ultraviolet light B phototherapy|DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Effectiveness Towards Improving Physical and Mental Health for Post-stroke Patients.
Status: COMPLETED
Conditions: Stroke|Brain Infarction|Brain Ischemia|Cerebral Infarction|Cerebrovascular Disorders
Interventions: BEHAVIORAL: Periodic health check program for post-stroke|BEHAVIORAL: Guiding the appropriate rehabilitation exercises|BEHAVIORAL: Motivational Interviewing|DEVICE: Functional near-infrared spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Ropivacaine Median Effective Concentration in Ultrasound-guided Supraclavicular Brachial Plexus Block
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: Latanoprost-PPDS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED)
Status: RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Tedopi|DRUG: Nivolumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Household Air Pollution on Lung Function Growth in Infants With Pneumonia in Sub-Saharan Africa
Status: ENROLLING_BY_INVITATION
Conditions: Pneumonia|Pollution; Exposure|Lung Function Decreased|Chronic Respiratory Disease|Pediatric Respiratory Diseases|Lungs; Developmental Disorder
Interventions: OTHER: Clean Air Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience
Status: RECRUITING
Conditions: Internalizing Mental Health Symptoms|Allostatic Load|Health Complaints
Interventions: BEHAVIORAL: STRIVE|BEHAVIORAL: Study Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria
Status: ENROLLING_BY_INVITATION
Conditions: Cystic Fibrosis|Nontuberculous Mycobacterial Lung Disease|Nontuberculous Mycobacterium Infection|Mycobacterium Infections|Mycobacterium; Pulmonary
Interventions: BIOLOGICAL: mycobacteriophage
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunochemotherapy or Chemotherapy in ALK-rearranged 5'-ALK NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Chemotherapy alone or Chemotherapy plus Immune Checkpoint Inhibitors with or without Bevacizumab|DRUG: Chemotherapy alone or Chemotherapy with or without Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HDL Particle Protection Study
Status: COMPLETED
Conditions: Dyslipidemia in Patients With Diabetes Mellitus
Interventions: DRUG: atovastatin 10 mg/day|DRUG: Atorvastatin 80 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma
Status: COMPLETED
Conditions: Larynx Cancer|Hypopharynx Cancer
Interventions: DRUG: DOCETAXEL|DRUG: Cisplatin|DRUG: 5-Fluoro-3-Pyridinecarboxylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vertical Ridge Augmentation Strategies
Status: NOT_YET_RECRUITING
Conditions: Alveolar Bone Resorption|Alveolar Ridge Trauma|Alveolar Bone Loss|Complication of Surgical Procedure
Interventions: PROCEDURE: VRA + d-PTFE membrane|PROCEDURE: VRA + e-PTFE membrane|PROCEDURE: VRA + customised Ti-mesh|PROCEDURE: VRA + RPM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: How to Treat Opiate Withdrawal in Neonates
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DRUG: Phenobarbital|DRUG: Chlorpromazine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Spiration Valve System for the Treatment of Severe Emphysema
Status: COMPLETED
Conditions: Empyhsema|Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Spiration Valve System|OTHER: Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Study to Compare Straumann® VivOss™ to Geistlich Bio-Oss® in Sinus Floor Augmentation.
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Straumann VivOss|DEVICE: Geistlich Bio-Oss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study (MACS)
Status: COMPLETED
Conditions: Pregnancies at Increased Risk of Preterm Birth
Interventions: DRUG: Multiple vs. single courses of antenatalcorticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Contribution of PRF in CDH in Children With Prothetic Patch Closure
Status: TERMINATED
Conditions: Congenital Diaphragmatic Hernias
Interventions: BIOLOGICAL: Biological functionalization of the prosthetic materials by PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HHHFA in COPD Patients, With Chronic Bronchitis
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: HHHFA Device|DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: 6-minute walk|DIAGNOSTIC_TEST: CT scan|OTHER: Medical Research Council dyspnea scale (MRC)|OTHER: St. George's Respiratory Questionnaire (SGRQ)|OTHER: COPD Assessment Test (CAT)|OTHER: Pittsburgh Sleep Quality Index (PSQI)|OTHER: CASA-Q|OTHER: Spirehealth Tag Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China
Status: RECRUITING
Conditions: Intracranial Arteriosclerosis|Stenosis Artery|Drug-Eluting Stents|Intracranial Artery Stenosis
Interventions: DEVICE: Drug-Eluting Stents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Motor Relearning Program(MRP) and aerobic exercise|OTHER: Motor Relearning Program(MRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spyglass-guided Lithotripsy Versus ESWL for Pancreatic Duct Stones
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatic Duct Stone
Interventions: PROCEDURE: Spyglass-guided lithotripsy|PROCEDURE: ESWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Hypertension Study of Ventavis® Inhalation Therapy in the Treatment of Patients With Pulmonary Arterial Hypertension (VENIS)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Iloprost (Ventavis BAYQ6256)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream for Very Dry, Irritated to Atopic Sensitive Skin.
Status: RECRUITING
Conditions: Atopic Dermatitis|Eczema, Atopic
Interventions: OTHER: Skin hydration|OTHER: Barrier function measurement|OTHER: Potential of hydrogen measurement (pH)|OTHER: Clinical evaluation of atopic dermatitis|OTHER: Quality of life assessment|OTHER: Assessment of the effect on itching and sleep disturbances|OTHER: Assessment of the tolerance of the study product or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Platform Switched Implant and Bone Level Alteration
Status: UNKNOWN
Conditions: Edentulous|Bone Resorption
Interventions: PROCEDURE: Subcrestal implant placement|PROCEDURE: Paracrestal implant placement|DRUG: prophylactic antibiotics|DEVICE: dental implant|RADIATION: x-ray examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Identification of Molecular Mechanisms of Coronary Instability in Homogeneous Subsets of Patients With Acute Coronary Syndromes for the Implementation of Precision Medicine
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Chronic Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: Venous blood samples, Biological samples analysis, Cardiology visit.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tenofovir/Levonorgestrel Intravaginal Ring and Tenofovir Intravaginal Ring
Status: UNKNOWN
Conditions: HIV|Contraception|Prevention|Anti-Retroviral Agent
Interventions: DRUG: TFV/LNG IVR|DRUG: TFV IVR|DRUG: Placebo IVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: Placebo|DRUG: rhEPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAVATAK in Patients With Stage IIIc or IV Malignant Melanoma to Extend Dosing to 48 Weeks (VLA-008 CALM Ext)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: CVA21
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT