pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects in a Phase Ⅱ Clinical Trial
Status: COMPLETED
Conditions: Corneal Epithelial Defect
Interventions: DRUG: lowe-dose ZKY001 eye drops|DRUG: Medium-dose ZKY001 eye drops|DRUG: ZKY001 simulated eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-diabetic Effects of Liraglutide in Adolescents and Young Subjects With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastasis From Malignant Tumor of Prostate
Interventions: DRUG: 177Lu-PSMA-I&T|DRUG: Abiraterone with Prednisone or Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tranexamic Acid In Reducing Blood Loss During Cesarean Section Because Of Placenta Previa
Status: COMPLETED
Conditions: Postpartum Haemorrage Sever Bleeding After Delivery
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Ara-C, Aclarubicin Combined With PEG-G-CSF for Initial Treatment of AML Patients
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: AraC|DRUG: Aclarubicin|DRUG: Peg-G-CSF|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test of Novel Drug for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Active JNJ Drug|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic and Pharmacodynamic Study of High-Dose Rifapentine and Moxifloxacin for Treatment of Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine|DRUG: Moxifloxacin|DRUG: Rifampin|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Ethambutol|DIETARY_SUPPLEMENT: Pyridoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Breakfast Compared With No Breakfast on Cognitive Function and Subjective State in 11-13 Year Old Children
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Breakfast: ready-to-eat-cereal and milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess the Safety, Tolerability and Efficacy of Latanoprost Liposome for Lower Eyelid Steatoblepharon
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Eyelid Steatoblepharon
Interventions: DRUG: POLAT-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1
Status: TERMINATED
Conditions: Tobacco Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Lidocaine After Arthroscopy on Knee
Status: UNKNOWN
Conditions: Postoperative Pain|Topical Anaesthesia
Interventions: DRUG: Lidocaine adhesive tape|OTHER: Adhesive tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Axillary Reverse Mapping in Preventing Lymphedema in Patients With Breast Cancer Undergoing Axillary Lymph Node Dissection
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DRUG: Isosulfan Blue|PROCEDURE: Axillary Lymph Node Dissection|PROCEDURE: Mapping|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Psychosocial Support for Pre-operative Pain and Distress
Status: COMPLETED
Conditions: Acute Pain
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Suggestion|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Safety Study of MM-10-001 in Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: lentinan|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infant Nutrition and Brain Development
Status: COMPLETED
Conditions: Healthy|Infant Development
Interventions: OTHER: Infant Formula: enriched level of myelin-relevant nutrients|OTHER: Infant formula: standard level of myelin-relevant nutrients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Compliance With Phosphorus Restricted Diet and Phosphate Binder Therapy in Hemodialysis Patients
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: education by DVD|BEHAVIORAL: Standard care|BEHAVIORAL: Education by DVD and dietician
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Nutriceutical formulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls
Status: COMPLETED
Conditions: Prehypertension|Blood Pressure|Abdominal Obesity|Adiposity
Interventions: OTHER: Jump rope exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: Mediterranean Diet|DIETARY_SUPPLEMENT: Curcumin Supplementation|DIETARY_SUPPLEMENT: Resveratrol Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Effect of Sofosbuvir/Velpatasvir/GS-9857 Fixed-Dose Combination on the Pharmacokinetics of a Representative Hormonal Contraceptive Medication, Norgestimate/Ethinyl Estradiol
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: SOF/VEL/VOX|DRUG: VOX|DRUG: Norgestimate/ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer (CRC)
Status: UNKNOWN
Conditions: Neoplasm Metastasis|Colorectal Cancer
Interventions: DRUG: 5-FU|DRUG: folinic acid|DRUG: irinotecan|DRUG: cetuximab|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of GBR 900 in a Single Ascending Dose Study in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GBR 900|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Xarelto for Thromboprophylaxis After Total Hip and Total Knee Arthroplasty
Status: RECRUITING
Conditions: Venous Thromboembolism|Arthroplasty
Interventions: DRUG: Rivaroxaban 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)
Status: NOT_YET_RECRUITING
Conditions: Venous Leg Ulcer (VLU)
Interventions: DRUG: EscharEx (EX-03)|DRUG: Placebo (Gel vehicle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Remimazolam and Propofol Effect on Oxygenation Reservoir During Diagnostic Gastric Endoscopy
Status: COMPLETED
Conditions: Diagnostic Gastric Endoscopy
Interventions: DRUG: Remimazolam besylate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Status: RECRUITING
Conditions: Malignant Solid Neoplasm|Metastatic Malignant Neoplasm in the Brain
Interventions: PROCEDURE: Conventional Surgery|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Online Adaptive Short-Course Radiation Therapy and Concurrent Chemotherapy for Muscle-Invasive Bladder Cancer
Status: TERMINATED
Conditions: Muscle Invasive Bladder Urothelial Carcinoma
Interventions: RADIATION: Daily Adaptive External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Point-of-care Diagnostic Technologies in MCH Services in Mozambique
Status: COMPLETED
Conditions: HIV|Syphilis|Anemia During Pregnancy
Interventions: DEVICE: PIMA® for quantitative analysis of CD4-count|DEVICE: Hemocue® (HemoCue AB, Angelhom, Sweden) for quantitative analysis of hemoglobin|DEVICE: SD Bioline® (Standard Diagnostics Inc., South-Korea) for qualitative analysis of syphilis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Management of Acute Heart Failure: Contribution of Ultrasound Daily "in Bed Patient" Adjustment on Therapy With Impact Measure on re Hospital Rate During 30 Days
Status: COMPLETED
Conditions: Heart Failure
Interventions: PROCEDURE: Transmitral flow estimation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak)
Status: TERMINATED
Conditions: Peripheral T-Cell Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Navelbine|DRUG: Doxorubicin Hydrochloride Liposome Injection|DRUG: Granulocyte-colony stimulating factor (G-CSF)|DRUG: Pegfilgrastim|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Leucovorin|DRUG: Methotrexate|DRUG: Doxorubicin Hydrochloride|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Carmustine|DRUG: Denileukin diftitox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress
Status: COMPLETED
Conditions: Hyperlipidemia|Blood Pressure|Oxidative Stress
Interventions: DRUG: Pterostilbene 50 mg twice daily|DRUG: Placebo|DRUG: Grape Extract|DRUG: Pterostilbene 125 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Laughter, Pregnancy, Anxiety and Llife Quality
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Life Style|Gestational Diabetes|Pregnancy Related
Interventions: OTHER: Laughter yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Effectiveness and Safety of (cTACE or DEB-TACE + FOLFOX Regimen HAIC) Combined With Camrelizumab and Apatinib Mesylas in the Treatment of Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|Non Metastatic Cancer
Interventions: DIAGNOSTIC_TEST: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Acuity 200 (Fluoroxyfocon A) contact lens|DEVICE: Acuity 100 (Hexafocon A) contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Type of a Pancreaticojejunostomy
Status: UNKNOWN
Conditions: Pancreaticojejunostomy After Pancreatic Head Resection
Interventions: PROCEDURE: Pancreaticojejunostomy without stiches through the pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise-meal Timing and Postprandial Glucose Control
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hyperglycemia, Postprandial|Physical Activity|Glucose Intolerance
Interventions: BEHAVIORAL: Physical activity|DIETARY_SUPPLEMENT: Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Registry of Pediatric Lupus Nephritis in China
Status: RECRUITING
Conditions: Lupus Nephritis|Children|Steroid|Immunosuppressive Treatment
Interventions: DRUG: Corticosteroid|DRUG: Hydroxychloroquine|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil|DRUG: Azathioprine|DRUG: Tacrolimus|DRUG: Cyclosporine A|DRUG: Rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study To Evaluate the Efficacy and Safety Of Bevacizumab, and Associated Biomarkers, In Combination With Paclitaxel Compared With Paclitaxel Plus Placebo as First-line Treatment Of Patients With Her2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Bevacizumab [Avastin]|DRUG: Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Of Lung InVolvement In ASMD
Status: RECRUITING
Conditions: Asmd, Visceral Type
Interventions: DIAGNOSTIC_TEST: eNose|DIAGNOSTIC_TEST: Volatile exhaled breath sample|DIAGNOSTIC_TEST: Condensate sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of a Oral Endotracheal Tube Fastener on Patients Intubated With Oral Endotracheal Tubes
Status: TERMINATED
Conditions: Respiratory Depression|Respiratory Failure|Ventilatory Depression
Interventions: DEVICE: Endotracheal Tube Fastener
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Safety and PK of Liquid Alpha₁-Proteinase Inhibitor (Human) in Treating Alpha₁-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha₁-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Liquid Alpha₁-PI|BIOLOGICAL: Prolastin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxia-inducible Factor-1 (HIF-1) Regulated Circulating Angiogenic Cells (CACs) Recruitment in Burn Wound Healing
Status: TERMINATED
Conditions: Wound Healing|Burns
Interventions: GENETIC: Healthy volunteers|OTHER: Burn volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment With Fresh Frozen Plasma and Rituximab (Mabthera) in Patients With Advanced Refractory Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Advanced Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Rituximab (Mabthera) , FFP (Fresh Frozen Plasma)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders
Status: COMPLETED
Conditions: Urea Cycle Disorders|Carbamoylphosphate Synthetase I Deficiency|Ornithine Transcarbamylase Deficiency|Citrullinemia
Interventions: BIOLOGICAL: Human Heterologous Liver Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Atypical Endometrial Hyperplasia and Endometrial Carcinoma Using Megestrol Acetate
Status: COMPLETED
Conditions: Atypical Endometrial Hyperplasia|Endometrial Carcinoma
Interventions: DRUG: Megestrol Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma
Status: WITHDRAWN
Conditions: CD19 Positive|Mantle Cell Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Etoposide|BIOLOGICAL: Filgrastim|DRUG: Melphalan|BIOLOGICAL: Rituximab|BIOLOGICAL: Umbilical Cord Blood-derived Natural Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube
Status: NOT_YET_RECRUITING
Conditions: Endotracheal Tube|Thirst|Dry Mouth
Interventions: PROCEDURE: 4°C frozen normal saline gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: imatinib mesylate|DRUG: nilotinib|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|GENETIC: microarray analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Year Study of Fluzone High-Dose Influenza Vaccine Compared With Fluzone® Vaccine in Adults Aged 65 Years and Older
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine High Dose|BIOLOGICAL: Trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Obstructive Sleep Apnea Treatment in Serious Mental Illness
Status: NOT_YET_RECRUITING
Conditions: Schizoaffective Disorder|Schizophrenia|Bipolar Disorder|Obstructive Sleep Apnea of Adult
Interventions: DEVICE: Automatic Positive Airway Pressure (APAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EZN-2279 in Patients With ADA-SCID
Status: COMPLETED
Conditions: ADA-SCID|Adenosine Deaminase Deficiency|Severe Combined Immunodeficiency
Interventions: BIOLOGICAL: EZN-2279|BIOLOGICAL: Adagen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Cockroach Sublingual Immunotherapy 2
Status: COMPLETED
Conditions: Asthma|Perennial Allergic Rhinitis
Interventions: BIOLOGICAL: Cockroach Sublingual Immunotherapy (SLIT) - Low Dose|OTHER: Placebo|BIOLOGICAL: Cockroach Sublingual Immunotherapy (SLIT) - High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application and Effectiveness of the Perioperative Position Management Based on the ADDIE Model in Patients With Congenital Microtia
Status: COMPLETED
Conditions: Congenital Microtia
Interventions: PROCEDURE: Utilization of a perioperative position management protocol for congenital microtia patients based on the ADDIE model.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Surgical Technique to Treat Acute Dorsal Trans-Scaphoid Perilunate Dislocations
Status: COMPLETED
Conditions: Operative Time|Grip Strength|Pain|Functional Status
Interventions: PROCEDURE: Open reduction and internal fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Isotretinoin, Interferon Alfa-2b, Docetaxel, and Estramustine in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa-2b|DRUG: docetaxel|DRUG: estramustine phosphate sodium|DRUG: isotretinoin|GENETIC: polyacrylamide gel electrophoresis|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Diamyd® in Patients With LADA (Latent Autoimmune Diabetes in Adult)
Status: COMPLETED
Conditions: Latent Autoimmune Diabetes in Adult (LADA)
Interventions: DRUG: rhGAD65 formulated in Alhydrogel® (Diamyd®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Midostaurin|DRUG: Cytarabine|DRUG: anthracycline ((daunorubicin or idarubicin): Induction Phase only
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Fluid Supplementation on Serum Bilirubin and Cardiorespiratory Parameters in Preterm Infants During Phototherapy
Status: COMPLETED
Conditions: Hyperbilirubinemia
Interventions: OTHER: extra fluid/iv fluid supplementation during phototherapy|OTHER: Non extra fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study GX-G3 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GX-G3 12.5 μg/kg or Placebo|DRUG: GX-G3 25 μg/kg or Placebo|DRUG: GX-G3 50 μg/kg or Placebo|DRUG: GX-G3 100 μg/kg or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Place of Ultrasound Guidance of Surgery Site in Surgery for Lumbar Canal Stenosis and Lumbar Disc Herniations
Status: UNKNOWN
Conditions: Lumbar Stenosis, Familial
Interventions: PROCEDURE: Ultrasound guidance in addition to radiographic guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomagnetic Characterization of Gastric Dysrhythmias III
Status: ENROLLING_BY_INVITATION
Conditions: Diabetics Without Symptoms of Gastroparesis|Diabetic Gastroparesis|Idiopathic Gastroparesis|Total or Partial Gastrectomy|Chronic Nausea|Functional Dyspepsia
Interventions: DIAGNOSTIC_TEST: magnetogastrogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating Therapies for Freezing of Gait
Status: UNKNOWN
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Cognitive Behavioural Therapy|BEHAVIORAL: Proprioceptive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atelectasis by Lung Ultrasonography in Cesarean Sections
Status: COMPLETED
Conditions: Atelectasis|Cesarean Section
Interventions: PROCEDURE: The Effect of General Anesthesia and Spinal Anesthesia on Postoperative Atelectasis by Lung Ultrasonography in Cesarean Sections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the Therapy With BRAINMAX® for the Treatment of Patients With Asthenia After COVID-19
Status: COMPLETED
Conditions: Asthenia|COVID-19
Interventions: DRUG: Ethyl methyl hydroxypyridine succinate + Meldonium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to See How Safe Curcumin is and How Well it Works When Used to Treat Mucositis in Patients Getting Chemotherapy
Status: TERMINATED
Conditions: Mucositis
Interventions: DRUG: Curcumin-MTD|DRUG: Mouthwash-standard pharmacy preparation|DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tivantinib (ARQ 197) Plus Cetuximab in EGFR Inhibitor-Resistant MET High Subjects
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|C-met Overexpression
Interventions: DRUG: Tivantinib (ARQ197)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capturing Infectious COVID-19 Asymptomatic Cases in Singapore
Status: WITHDRAWN
Conditions: Covid19|SARS CoV-2
Interventions: DIAGNOSTIC_TEST: BD Veritor Plus System for Rapid Detection of SARS CoV-2|DIAGNOSTIC_TEST: rt-PCR|DIAGNOSTIC_TEST: viral culture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Fiber on Glycemic Index
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 8 g Polydextrose|DIETARY_SUPPLEMENT: 12 g Polydextrose|DIETARY_SUPPLEMENT: 16 g Polydextrose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Population Pharmacokinetics of Edoxaban in Chinese Patients With Non-Valvular Atrial Fibrillation
Status: RECRUITING
Conditions: Non-Valvular Atrial Fibrillation
Interventions: DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AL-4943A ophthalmic solution|DRUG: Olopatadine hydrochloride ophthalmic solution, 0.2%|DRUG: Olopatadine hydrochloride ophthalmic solution, 0.1%|DRUG: AL-4943A ophthalmic solution vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Addition of Raltegravir (MK-0518) to PI- or NNRTI-Based ART Regimens in HIV Infected Subjects With Undetectable Viral Load
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir (MK-0518)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition
Status: COMPLETED
Conditions: CLABSI - Central Line Associated Bloodstream Infection
Interventions: DRUG: Sodium Citrate 4% Inj Syringe 3Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 24-Week Open Label Extension to a Randomized, 6-Week Double Blind, Placebo Controlled Study, to Evaluate the Safety and Tolerability of Flexible Doses of Extended Release OROS® Paliperidone in the Treatment of Geriatric Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER OROS®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Desflurane Versus Sevoflurane on Postoperative Recovery
Status: COMPLETED
Conditions: Postoperative Recovery|Postoperative Delirium|Difference in Pharmakokinetics of Volatile Anesthetics
Interventions: DRUG: Desflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Endocrine Therapy in HR Positive and HER2 Negative Premenopausal Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dalcelli、Exemestane、Gosserine|DRUG: Docetaxel for injection、Epirubicin hydrochloride for injection、Cyclophosphamide for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm|Obesity-Related Malignant Neoplasm
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|OTHER: Educational Intervention|OTHER: Health Promotion and Education|OTHER: Internet-Based Intervention|OTHER: Interview|OTHER: Medical Device Usage and Evaluation|BEHAVIORAL: Mindfulness Relaxation|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Green Vegetables and Women's Health
Status: COMPLETED
Conditions: Dietary Modification
Interventions: OTHER: Broccoli and Brussels Sprouts|DIETARY_SUPPLEMENT: Cruciferous Complete|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Once-Daily Oral Avatrombopag Tablets Used in Subjects With Chronic Liver Diseases and Thrombocytopenia Prior to Elective Surgical or Diagnostic Procedures
Status: COMPLETED
Conditions: Thrombocytopenia Related to Chronic Liver Disease
Interventions: DRUG: Avatrombopag|DRUG: Avatrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects
Status: COMPLETED
Conditions: Post-menopausal Osteoporosis
Interventions: DRUG: Ibandronate|DRUG: Risedronate|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal Cancer
Status: RECRUITING
Conditions: Colon Cancer|Colorectal Cancer
Interventions: DRUG: MRTX849|DRUG: Irinotecan|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Recurrent Non-small Cell Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: auranofin|DRUG: sirolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: Online cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exparel vs Exparel Plus ACB in TKAs
Status: WITHDRAWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Liposomal bupivacaine|DRUG: Ropivacaine|DRUG: Epinephrine|DRUG: Clonidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch.
Status: TERMINATED
Conditions: Headache
Interventions: DRUG: Sphenopalatine ganglion Block|PROCEDURE: Epidural blood patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 Combine With Toripalimab in Patients With Advanced HCC and Other Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumors
Interventions: DRUG: HBM4003 and Triprilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Safety of a 3 Weeks Sitagliptin Treatment in HCC Patients Undergoing Liver Resection
Status: COMPLETED
Conditions: Hepato Carcinoma
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Sub-dissociative Dose Ketamine Injection Versus Infusion for Analgesia in the Emergency Department
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine IV Infusion|DRUG: Ketamine IV push
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a NeuroAD System, for the Treatment of Alzheimer Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DEVICE: NeuroAD|DEVICE: Sham TMS+Cog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic in Irritable Bowel Syndrome (IBS) Patients With Diarrhea
Status: COMPLETED
Conditions: IBS
Interventions: DIETARY_SUPPLEMENT: Bio-25|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Conjunctival Intraepithelial Neoplasia|Corneal Intraepithelial Neoplasia
Interventions: DRUG: Mitomycin C|DRUG: Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS)
Status: UNKNOWN
Conditions: Infarction, Anterior Cerebral Artery
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center Human Study to Evaluate the Efficacy and Safety of ®GI Flora in Subjects With Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: GI Flora|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Half of the Usual Radiotracer Dose in SPECT
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: RADIATION: 1/2 dose of 99mTc OR 201Tl tracers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Melanoma|Ovary Cancer|Pancreatic Cancer|Solid Tumor
Interventions: DRUG: ENB003|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EEP in Patients With Urodynamically Proven DU/DA
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms|Lower Urinary Tract Obstructive Syndrome|Detrusor Underactivity|Detrusor Areflexia|Prostatic Hyperplasia
Interventions: PROCEDURE: Endoscopic enucleation of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Varenicline on Brain Activity During Nicotine Abstinence
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine
Status: COMPLETED
Conditions: Pain, Postoperative|Major Abdominal Surgery
Interventions: PROCEDURE: TAP block|PROCEDURE: Epidural analgesia|DRUG: EXPAREL|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Driving Rehabilitation in Virtual Environments (NeuroDRIVE) as an Adjunctive Intervention for Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: VR Driving
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy
Status: RECRUITING
Conditions: Erb's Palsy
Interventions: OTHER: Modified constraint-induced movement therapy|OTHER: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)
Status: TERMINATED
Conditions: Sanfilippo Syndrome
Interventions: BIOLOGICAL: rhHNS-10 mg|BIOLOGICAL: rhHNS-45 mg|BIOLOGICAL: rhHNS-90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketotifen Ophthalmic Solution With Emedastine in Patients With Seasonal Allergic Conjunctivitis
Status: COMPLETED
Conditions: Seasonal Allergic Conjunctivitis
Interventions: DRUG: Ketotifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Brodalumab in Adolescents From 12 to 17 Years of Age With Moderate-to-severe Plaque Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Brodalumab|DRUG: Ustekinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The AVATAR Trial: Applying VAcuum To Accomplish Reduced Wound Infections
Status: TERMINATED
Conditions: Post-laparoscopy Umbilical Port-site Wound Infection
Interventions: PROCEDURE: Application of vacuum|PROCEDURE: No vacuum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SecurAcath Versus Statlock for PICC Securement
Status: COMPLETED
Conditions: Patients With Any Condition Who Need a PICC for IV Therapy
Interventions: DEVICE: SecurAcath|DEVICE: StatLock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect Of Topical Prostaglandin F2α Analogs,Fractional CO2 Laser, Excimer Laser Or Their Combination In Treatment Of Vitiligo
Status: UNKNOWN
Conditions: Vitiligo|Excimer Laser|Fractional CO2 Laser
Interventions: DRUG: Topical travoprost 0.004% solution|DEVICE: Fractional CO2 laser|DEVICE: Excimer laser|OTHER: Combination therapy|OTHER: Excimer laser and travoprost|OTHER: fractional CO2 laser and topical travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Irritable Bowel Syndrome With Diarrhea
Interventions: DIETARY_SUPPLEMENT: Two probiotic strains (L. plantarum and L. acidophilus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics and Safety/Tolerability of BR-UPS (Ulipristal Acetate) 5 mg Tablet With Inisia (Ulipristal Acetate) 5 mg Tablet
Status: WITHDRAWN
Conditions: Uterine Myoma
Interventions: DRUG: BR-UPS 5 mg tablet, Inisia 5 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin for Non-Small Cell Lung Cancer With KRAS or EGFR Activation
Status: COMPLETED
Conditions: Carcinoma, Non-small Cell Lung
Interventions: BIOLOGICAL: REOLYSIN®|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azilsartan Medoxomil in Hypertensive pAtients With Stable Ischemic Heart Disease and DiabEtes MEllitus.
Status: COMPLETED
Conditions: Arterial Hypertension|Diabetes Mellitus|Stable Chronic Angina
Interventions: DRUG: Azilsartan Medoxomil 40 MG Oral Tablet [Edarbi]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Oral niacinamide, 1 gram daily|DRUG: Oral niacinamide, 3 gram daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: PDC-1421 Treatment in Adult Patients With ADHD
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: PDC-1421 Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Probiotics on Intestinal Permeability in Gastrointestinal Cancer Patients in Chemotherapy
Status: COMPLETED
Conditions: Intestinal Permeability|Gastrointestinal Irritation|Mucositis
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT