pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development of a Breath Test for Monitoring Patients With Liver Disease
Status: COMPLETED
Conditions: Fatty Liver|Cirrhosis
Interventions: DRUG: 13C-Methacetin|DEVICE: Breath ID Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of SI-R21204 Versus Nano-hybrid Resin Composite: A Prospective Controlled Clinical Trial
Status: COMPLETED
Conditions: Caries
Interventions: DEVICE: SI-R21204 resin composite|DEVICE: Nanohybrid resin composite
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chronic Exenatide Therapy on Beta Cell Function and Insulin Sensitivity in T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin|DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of an Investigational Drug (MK-686) in Patients With Osteoarthritis (0686-006)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0686
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)
Status: COMPLETED
Conditions: Coagulation Protein Disorders|Blood Loss, Surgical|Perioperative Care
Interventions: BIOLOGICAL: Beriplex® P/N|BIOLOGICAL: Fresh Frozen Plasma (FFP) and Beriplex® P/N|OTHER: Fresh Frozen Plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Methyl Aminolaevulinate Photodynamic Therapy With and Without Er:YAG Laser in Actinic Cheilitis
Status: COMPLETED
Conditions: Actinic Cheilitis
Interventions: DRUG: Er:YAG AFL-PDT|DRUG: MAL-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting
Status: WITHDRAWN
Conditions: Childhood Acute Lymphoblastic Leukemia|Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies|Ewing Sarcoma|Vomiting in Infants and/or Children|Osteosarcoma
Interventions: PROCEDURE: electroacupuncture therapy|OTHER: questionnaire administration|PROCEDURE: electroacupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Status: UNKNOWN
Conditions: Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Interventions: OTHER: Salivary bacterial and pH level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deep Vein Thrombosis Prophylaxis Adherence: Enoxaparin vs Rivaroxaban
Status: UNKNOWN
Conditions: Deep Vein Thrombosis|Venous Thromboembolism
Interventions: DRUG: Enoxaparin 40 milligram/0.4 milliliter Injectable Syringe 0.4 milliliters|DRUG: Rivaroxaban 10 milligram Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Role of Postoperative Radiotherapy in Patients With IIIA(N2) Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage IIIA|Radiotherapy
Interventions: RADIATION: PORT|DRUG: Platinum-based two drug chemotherapy (cisplatin/carboplatin + vinorelbine or cisplatin/carboplatin + pemetrexed regimen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bisphosphonates and Nutritional Supplementation After a Hip Fracture
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: Risedronate|OTHER: Nutritional supplement|DIETARY_SUPPLEMENT: Calcium and vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect Of Traınıng On Breastfeedıng Gıven To Fathers On Breastfeedıng, Parent-Baby Bondıng And Breastfeedıng Self-Effıcacy Level
Status: RECRUITING
Conditions: Breast Feeding
Interventions: BEHAVIORAL: Provide breastfeeding education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Creating Live Interactions to Mitigate Barriers
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Commercially available computerized training|OTHER: Optimized social skills training|OTHER: Unstructured support group sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PIRA vs Standard Preoperative Education
Status: COMPLETED
Conditions: Anesthesia|Anesthesia Emergence Delirium|Procedural Anxiety
Interventions: OTHER: Pediatric Interactive Relational Agent (PIRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endothelial Cell Loss in Pseudophakic Patients Receiving a Paul Glaucoma Drainage Device With Its Tube Inserted in the Anterior Versus Posterior Chamber: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Glaucoma
Interventions: DEVICE: Paul glaucoma drainage device (GDD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of the Co-administration of Three Drugs for Trachoma and Lymphatic Filariasis Elimination
Status: COMPLETED
Conditions: Parasitic Diseases|Bacterial Diseases
Interventions: DRUG: triple co administration at once of the combination of Albendazole + ivermectin + azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic Urticaria
Status: COMPLETED
Conditions: Cold Urticaria|Cold Contact Urticaria|Symptomatic Dermographism|Symptomatic Dermatographism|Cholinergic Urticaria
Interventions: DRUG: CDX-0159
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-C )
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: COMBINATION_PRODUCT: Emergency Stroke Unit based on 0.23-T MRI|COMBINATION_PRODUCT: Standard stroke unit adherent to guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Possible Difference in Development of Type 2 Diabetes Between Caucasian and Japanese Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: OTHER: Oral Glucose Tolerance Test (OGTT)|OTHER: Euglycaemic hyperinsulinaemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia|Acute Myeloid Leukemia in Remission|Hematopoietic Cell Transplantation Recipient|Minimal Residual Disease|Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia
Interventions: DRUG: Fludarabine|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|RADIATION: Total Marrow Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Sulfadoxine/ Pyrimethamine Tablets in Healthy Subjects Under Fasting Conditions
Status: UNKNOWN
Conditions: Bioequivalence
Interventions: DRUG: Maldox tablets|DRUG: G-COSPE® tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: mCBCT in Combination With ENB for the Diagnosis of PPNs
Status: RECRUITING
Conditions: Peripheral Pulmonary Nodules|Lung Cancer
Interventions: DEVICE: Electromagnetic Navigation Bronchoscopy (superDimension™ Navigation System) and Mobile Cone-Beam CT (Cios Spin)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy
Status: RECRUITING
Conditions: NSCLC|Renal Cell Carcinoma|Breast Carcinoma|Melanoma|Brain Metastases, Adult|Non-small Cell Lung Cancer|SCLC|Small-cell Lung Cancer
Interventions: RADIATION: single fraction stereotactic radiosurgery (SSRS)|RADIATION: fractionated stereotactic radiosurgery (FSRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy
Status: COMPLETED
Conditions: Breast Carcinoma|Breast Disorder
Interventions: DEVICE: Blossom|OTHER: Breast-Q -Reconstruction module (preoperative) version 2.0 satisfaction with breasts questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evolution of Corporeal Composition in the PeriOperative Period
Status: COMPLETED
Conditions: Gastrointestinal Cancer (Esophagus, Gastric, Pancreatic, Hepatic, Colorectal and Anal)|Lung Cancer
Interventions: DEVICE: Bioelectrical Impedance Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-Label Study to Investigate the Pharmacokinetics of Omacetaxine Mepesuccinate
Status: COMPLETED
Conditions: Hematologic Malignancies|Solid Tumors
Interventions: DRUG: omacetaxine mepesuccinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Tuberculosis Vaccine, MVA85A, Administered by the Aerosol Route and the Intradermal Route
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Aerosol inhaled MVA85A|BIOLOGICAL: Intradermal MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ph1 Marinol Interaction Study - Part 2 - 1
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: Placebo|DRUG: Dronabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Neuromodulation With Low Frequency-Pulsed Electromagnetic Fields
Status: COMPLETED
Conditions: Electromagnetic Fields|Neuronal Plasticity|Transcranial Magnetic Stimulation
Interventions: DEVICE: CTU Mega 20 real device|DEVICE: CTU Mega 20 sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Immune Response After a Booster Dose of a Quadrivalent Meningococcal (MenACYW) Conjugate Vaccine When Administered Alone or Concomitantly With a Licensed Meningococcal Serogroup B Vaccine, in Participants Who Received Primary Quadrivalent Meningococcal Conjugate Vaccine (MCV4)
Status: COMPLETED
Conditions: Meningococcal Immunisation (Healthy Volunteers)
Interventions: BIOLOGICAL: Meningococcal polysaccharide (serogroups A, C, Y, and W) tetanus toxoid Conjugate vaccine MenACYW Conjugate vaccine|BIOLOGICAL: Meningococcal Group B vaccine (Trumenba®)|BIOLOGICAL: Meningococcal group B vaccine (Bexsero®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Perceptions and Quality of Life Associated With the Use of Olapatadine 0.2% for the Treatment of Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine hydrochloride ophthalmic solution, 0.2% (Pataday®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2, Multi-center, Open-label, Dose-escalation Study of Elotuzumab(Humanized Anti-CS1 Monoclonal IgG1 Antibody) and Bortezomib in Subjects With Multiple Myeloma Following One to Three Prior Therapies.
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab (HuLuc63)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
Status: RECRUITING
Conditions: Femoral Neck Fractures
Interventions: DRUG: Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Status: COMPLETED
Conditions: Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy|BEHAVIORAL: Wait-list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants
Status: COMPLETED
Conditions: Spondylitis, Ankylosing|Arthritis, Rheumatoid|Psoriasis|Arthritis, Psoriatic
Interventions: DRUG: Infliximab; observational study|DRUG: Methotrexate; observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Cancer|Non-Small-Cell Lung Cancer|Triple Negative Breast Neoplasms|Squamous Cell Cancer of Head and Neck|Small Cell Lung Cancer|Gastroesophageal Cancer|Melanoma|Cervical Cancer|Advanced Solid Tumours
Interventions: DRUG: AZD8701|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IB1,IB2,IIA1)
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: OTHER: Total Laparoscopic or Robotic Radical Hysterectomy|OTHER: Total Abdominal Radical Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (1,3)-Béta-D-Glucan Levels at Diagnosis of Juvenile Idiopathic Arthritis and Its Correlation With Activity's Disease : a Cohort Sudy
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DIAGNOSTIC_TEST: The Juvenile Disease Activity Score (JADAS)|BIOLOGICAL: (1-3)-ß-D-Glucan (BDG) assay (Fungitell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NICUSeq: A Trial to Evaluate the Clinical Utility of Human Whole Genome Sequencing (WGS) Compared to Standard of Care in Acute Care Neonates and Infants
Status: COMPLETED
Conditions: Rare Diseases
Interventions: OTHER: clinical whole genome sequencing (cWGS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Tremor Retrainer Software Application for Functional Tremor
Status: RECRUITING
Conditions: Functional Movement Disorder|Functional Neurological Disorder|Functional Neurological Symptom Disorder
Interventions: DEVICE: Tremor Retrainer Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Brain Disease|Central Nervous System Diseases|Nervous System Diseases|Cardiovascular Diseases
Interventions: DEVICE: Deep Brain Stimulation (DBS) of the Motor Thalamus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adaptions and Resiliency to Multi-Stressor OpeRations
Status: RECRUITING
Conditions: Musculoskeletal Injury|Hypogonadism
Interventions: DRUG: Goserelin 3.6 MG|OTHER: Multi-Stressor Training|DRUG: Testosterone gel (AndroGel 5g)|DRUG: Testosterone gel (AndroGel 1.25g)|DRUG: Estradiol / Levonorgestrel Transdermal System [Climara Pro]|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Sarilumab SAR153191 (REGN88)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Fertility Issues|Luteal Phase Defect|Infertility Unexplained
Interventions: DRUG: Progesterone Vaginal Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capsulized Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis Patients
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: OTHER: Fecal transplantation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Usability of a New Injector to Administer Contrast Media Into Humans for Diagnostic Purposes
Status: COMPLETED
Conditions: Computed Tomography
Interventions: DEVICE: Centargo injector (BPI 1000045)|DEVICE: Stellant MP injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Technique of Per-Operative Radiotherapy (RPO) by Papillon +TM in Localized Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Localized Breast Cancer
Interventions: DEVICE: Papillon +TM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Predictive Value of the MolecuLight i:X Imaging Device to Predict the Presence of Bacteria in Chronic Wounds
Status: COMPLETED
Conditions: Wounds
Interventions: DEVICE: MolecuLight i:X Imaging Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Efficacy of "Mindtesion"is Measuring Attentional and the Startle Response Dysregulation in Children and Adolescents Suffering From Attention Deficit Disorder: With and Without Medication.
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DEVICE: MT1 Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Adjunctive Use of Lavender and Peppermint Essential Oils
Status: COMPLETED
Conditions: Joint Diseases
Interventions: DIETARY_SUPPLEMENT: Adjunctive use of lavender and peppermint essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Variable Types of Preconditioning Upon the Inotrope Score in Adult Patients, Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: A pharmacologic cardiac preconditioning (Sevoflurane)|PROCEDURE: B ischeamic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individualized Antithrombotic Therapy for Patients With Ischemic Cerebrovascular Disease
Status: UNKNOWN
Conditions: Cerebrovascular Disease
Interventions: DRUG: Desirable TEG|DRUG: Undesirable TEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of 448kilohertz Capacitive Resistive Monopolar Radiofrequency Stimulation in Chronic Shoulder Pain
Status: UNKNOWN
Conditions: Chronic Shoulder Pain
Interventions: DEVICE: Experimental: 448 kilohertz Capacitive Resistive Monopolar Radiofrequency stimulus|OTHER: Sham comparator|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Celecoxib and Etoricoxib on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Selecoxib|DRUG: Etoricoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CRPS - Diagnostics, Pathophysiological Mechanisms, and Response to Treatment With Noninvasive Brain Stimulation
Status: COMPLETED
Conditions: Transcranial Magnetic Stimulation|Complex Regional Pain Syndrome of Upper Limb (Disorder)
Interventions: DEVICE: Sham nrTMS and open phase|DEVICE: Active nrTMS and open phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers
Status: COMPLETED
Conditions: Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)
Interventions: DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: cobitolimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA|OTHER: Placebo (matched to ELX/TEZ/IVA)|OTHER: Placebo (matched to IVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Stomach|GastroEsophageal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: mFOLFOX|DRUG: FLOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Durvalumab for Tumor-Stage Cutaneous T-Cell Lymphoma
Status: WITHDRAWN
Conditions: Cutaneous T Cell Lymphoma
Interventions: DRUG: Durvalumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Affirmative Coping Skills Intervention to Improve Mental and Sexual Health of Sexual and Gender Minority Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Issue|Hiv|Stigma, Social|Coping Skills
Interventions: BEHAVIORAL: AFFIRM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Surgical Outcomes Between Avulsion Fracture of the AT and Conventional ATR--a Retrospective Study
Status: COMPLETED
Conditions: Avulsion Fracture of the Achilles Tendon|Achilles Tendon Rupture
Interventions: PROCEDURE: fixation|PROCEDURE: primary repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research of Exenatide for Overweight/Obese PCOS Patients With IGR
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Overweight and Obesity|Disorder of Glucose Regulation
Interventions: DRUG: Exenatide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ Transplantation
Status: COMPLETED
Conditions: Lymphoproliferative Disorder
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: methylprednisolone|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy.
Status: COMPLETED
Conditions: Carcinoma, Non- Small Cell Lung
Interventions: DRUG: Durvalumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Probiotics for Prevention of NEC in Preterm VLBW Infants
Status: COMPLETED
Conditions: Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Of Quantitative Flow Ratio (QFR) - Derived Virtual Angioplasty
Status: UNKNOWN
Conditions: Coronary Occlusion
Interventions: DIAGNOSTIC_TEST: Quantitative Flow Ratio (QFR) measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Etrasimod Versus Placebo as Induction Therapy in Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas
Status: TERMINATED
Conditions: Neurofibroma
Interventions: DRUG: LS11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Ivermectin|DRUG: Hydroxychloroquine|BEHAVIORAL: personal protective Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Zataria Multiflora Boiss (Shirazi's Thyme) on Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Fatty Liver|Fatty Liver, Nonalcoholic
Interventions: DIETARY_SUPPLEMENT: Thyme|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: budesonide/formoterol|DRUG: fluticasone/salmeterol|DRUG: mometasone/formoterol|DRUG: Prednisone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of N-acetylcysteine on Muscle Fatigue in Hemodialysis
Status: COMPLETED
Conditions: End-Stage Renal Disease|Dialysis|Hemodialysis
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Tocolysis With Terbutaline for Suspected Fetal Distress
Status: COMPLETED
Conditions: Nonreassuring Fetal Status
Interventions: DRUG: Terbutaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endovascular Management of Combined Common Femoral and Superficial Femoral Arteries Lesions
Status: NOT_YET_RECRUITING
Conditions: Lower Limb Ischemia
Interventions: PROCEDURE: angioplasty and stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
Status: COMPLETED
Conditions: Chronic Pain|Opiate Dependence|Lower Back Pain
Interventions: DEVICE: iTBS to the left dlPFC|DEVICE: Sham iTBS to the left dlPFC|DEVICE: cTBS to the mPFC|DEVICE: Sham cTBS to the mPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of Ustekinumab in Pediatric Participants
Status: RECRUITING
Conditions: Crohn Disease|Colitis, Ulcerative|Arthritis, Psoriatic
Interventions: DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension?
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Hypertension
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pregabalin in Patients With Radiotherapy-related Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Ruxolitinib|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pharmacokinetics and Safety of Tegoprazan in Subjects With Hepatic Impairment and Healthy Controls
Status: UNKNOWN
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: Tegoprazan 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene
Status: COMPLETED
Conditions: Leber's Congenital Amaurosis
Interventions: DRUG: QR-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACT-ICU Study: Activity and Cognitive Therapy in the Intensive Care Unit
Status: COMPLETED
Conditions: Brain Injuries|Dementia|Myopathies|Muscle Disorders
Interventions: BEHAVIORAL: Behavioral: Physical and functional rehabilitation|BEHAVIORAL: Behavioral: Cognitive, physical, & functional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Adaptive Trial Design Examining the Pharmacokinetic and Pharmacodynamic Effects of Modified Release Amphetamine (HLD100, Formulations B, C and E)) in Adolescents and Children With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder
Interventions: DRUG: HLD100-B|DRUG: HLD100-C|DRUG: HLD100-E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 3-V Bioscience-2640 to Reduce de Novo Lipogenesis in Subjects With Characteristics of Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: 3-V Bioscience-2640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Downregulation of HIV-1 When Raltegravir is Added to a Virologically Suppressed HAART Regimen
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Evaluation of Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of JPI-289 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: JPI-289|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Area of Internal Limiting Membrane Peeling (ILM) Peeling on Anatomical Outcomes in Macular Hole Surgery
Status: COMPLETED
Conditions: Macular Hole
Interventions: PROCEDURE: ILM peeling surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Magnetic Therapy In Bladder Dysfunction And Quality Of Life In Paraplegic Patients
Status: COMPLETED
Conditions: Paraplegia|Spinal Cord Injuries
Interventions: DEVICE: magnetic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease
Interventions: PROCEDURE: Serratus anterior plane block|PROCEDURE: erector spinae plane blocks|DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sufentanil Administration by Paramedics in Acute Trauma
Status: RECRUITING
Conditions: Injury Traumatic|Pain, Acute
Interventions: DRUG: Sufentanil intravenous administration followed consultation of remote physician|DRUG: Sufentanil intravenous administration based on paramedic competency
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Nutritional Approach in Combination With Cognitive Stimulation on Child Cognitive Abilities
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: StimuLearn Intervention|BEHAVIORAL: Without StimuLearn intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effectivity Gas Extraction to Prevent Anesthesiologists Waste Gas Exposure of Sevofluorane During Pediatric Induction
Status: NOT_YET_RECRUITING
Conditions: Unrecognized Condition
Interventions: DIAGNOSTIC_TEST: Urine analysis to determine the presence of hexafluoroisopropanol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of the Addition of Bevacizumab to VOIT Regimen for Relapsed/Refractory Pediatric Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Bevacizumab|DRUG: Temozolomide|DRUG: Vincristine|DRUG: Irinotecan|DRUG: Cefixime
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Antibiotherapy Duration for Infections on Implantable Extra Cardiac Devices Leads
Status: NOT_YET_RECRUITING
Conditions: Cardiac Devices Infection
Interventions: DRUG: 14-day antibiotic therapy|DRUG: 28-day antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation in TAVI and SAVR Patients With Iron Deficiency
Status: NOT_YET_RECRUITING
Conditions: Aortic Stenosis|Iron-deficiency
Interventions: DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of KH-1 for Stimulating Autophagy in Non-diabetic Adults With Elevated Blood Glucose Concentration
Status: COMPLETED
Conditions: PreDiabetes|Aging
Interventions: DIETARY_SUPPLEMENT: KH-1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
Status: COMPLETED
Conditions: Ewing's Family Tumors|Renal Tumors|Hepatoblastoma|Rhabdomyosarcoma|Soft Tissue Sarcoma|Primary Malignant Brain Neoplasms|Retinoblastoma|Medulloblastoma|Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET)|Atypical Teratoid/Rhabdoid Tumor (AT/RT)|CNS Tumors|Germ Cell Tumors
Interventions: DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Mesna|BIOLOGICAL: G-CSF|DRUG: Busulfan|DRUG: Melphalan|DRUG: Thiotepa|BIOLOGICAL: Autologous stem cell infusion|RADIATION: Radiation|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Leukapheresis|DRUG: Anti-seizure prophylaxis|DRUG: Ursodiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of an Aromatic Botanical Extract on Respiratory Health.
Status: COMPLETED
Conditions: Respiratory Health
Interventions: DIETARY_SUPPLEMENT: Teramune Botanical Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer
Status: COMPLETED
Conditions: Limited Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer|Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Tobacco Use Disorder
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|OTHER: counseling intervention|OTHER: internet-based intervention|BEHAVIORAL: telephone-based intervention|OTHER: educational intervention|DRUG: nicotine replacement therapy|OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation|RADIATION: MRI|OTHER: Androgen Deprivation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Topical Arnica & Ledum on Bruise Reduction in HNV
Status: UNKNOWN
Conditions: Bruise, Contusion
Interventions: OTHER: Arnica montana, Ledum palustre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupoint Massage and Aromatherapy Intervention in Elderly People With Mild Cognitive Impairment in Nursing Institutions
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: OTHER: Acupoint Massage|OTHER: lavender essential oil|OTHER: Acupoint Massage and lavender essential oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of Pentaxim in South African Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Haemophilus Infections|Pertussis|Poliomyelitis
Interventions: BIOLOGICAL: Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of the Immunogenicity, Safety, and Tolerability of rF1V Vaccine With CpG 1018® Adjuvant Compared With rF1V Vaccine in Adults 18 to 55 Years of Age
Status: COMPLETED
Conditions: Plague, Pneumonic|Plague|Vaccine-Preventable Diseases
Interventions: BIOLOGICAL: rF1V vaccine and CpG 1018® adjuvant|BIOLOGICAL: rF1V vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Remote Ischemic Preconditioning on Postoperative Complications in Visceral Surgery
Status: UNKNOWN
Conditions: Postoperative Complication
Interventions: DEVICE: RIPC with a tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Hyoscine- Bromide on Duration of the First Stage of Labor
Status: RECRUITING
Conditions: Labor
Interventions: DRUG: hyoscine butylbromide|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CD5789 (Trifarotene) 50μg/g Cream Versus Vehicle Cream in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CD5789 (trifarotene) 50μg/g cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Relationship Between Balance, Core Stabilization and Foot Posture in Kickboxers
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DIAGNOSTIC_TEST: y balance test, core endurance and strength test, foot posture ındex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess the PK, PD, Safety and Immunogenicity of Single IV Infusion of BCD-264 and Darzalex in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BCD-264|DRUG: Darzalex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Low FODMAPs Diet vs. Specific Dietary Advice in Patients With IBS Diarrheal Variant
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Diet low in FODMAPs|DIETARY_SUPPLEMENT: Specific dietary advice for IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: REQUIP (Ropinirole Hydrochloride) IR Long-Term Phase 4 Study
Status: COMPLETED
Conditions: Parkinson Disease|Parkinson's Disease
Interventions: DRUG: ROP|DRUG: ROP+L-Dopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopic Bullectomy Versus Thoracoscopic Bullectomy With Pleurodesis in Primary Spontaneous Pneumothorax
Status: UNKNOWN
Conditions: Thoracic Surgical Procedures
Interventions: PROCEDURE: Thoracoscopic bullectomy alone|PROCEDURE: Thoracoscopic bullectomy with pleurodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT