pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Single-Agent Lenalidomide in Subjects With Recurrent Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: CC-5013
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Effectiveness of Ureteral Stents MEMOKATH ® 051 in Chronic Strictures of the Ureter
Status: COMPLETED
Conditions: Ureteral Obstruction
Interventions: PROCEDURE: Insertion of Memokath 051
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicomponent Intervention to Increase HIV Risk Perceptions and PrEP Initiation Among Black Men Who Have Sex With Men
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Risk Perception|PrEP
Interventions: BEHAVIORAL: Multi-component intervention strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Hylan GF-20 on Joint Reaction Forces and Kinematic Patterns During Gait in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: Hylan G-F 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Combined Ultrasound and Fluoroscopy Guided Cervical Transforaminal Injection
Status: COMPLETED
Conditions: Chronic Cervical Radicular Pain
Interventions: PROCEDURE: Ultrasound guidance with fluoroscopic confirmation|PROCEDURE: Fluoroscopic guidance with ultrasonographic confirmation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study in Subjects With Moderate Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: ALX-101 Gel Vehicle|DRUG: ALX-101 Gel 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of REM-422 in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Metastatic Adenoid Cystic Carcinoma|Recurrent Adenoid Cystic Carcinoma
Interventions: DRUG: REM-422
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Positive Breast Cancer
Interventions: DRUG: TAK-228|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions
Status: COMPLETED
Conditions: Congenital Heart Disease|Sedated for Cardiac Catheterization
Interventions: DRUG: control|DRUG: Ket10|DRUG: Ket20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Double-Expressor Lymphoma|High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements|High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Etoposide|BIOLOGICAL: Loncastuximab Tesirine|DRUG: Prednisone|BIOLOGICAL: Rituximab|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laparoscopic Pylorus Preserving Gastrectomy Versus Laparoscopic Distal Gastrectomy
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopic PPG|PROCEDURE: Laparoscopic DG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant
Status: COMPLETED
Conditions: Acute Biphenotypic Leukemia|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hematopoietic Cell Transplantation Recipient
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain
Status: COMPLETED
Conditions: Sternal Wound Infection|Sternal Non-union|Pain|Mediastinitis
Interventions: DEVICE: SternaLock Rigid Fixation Plates|DEVICE: wire (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: COMT on Aspirin Platelets Effects (CAPE)
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: Aspirin 81 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: DRUG: Nimotuzumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interpretation of Health News Items Reporting Results of Randomized Controlled Trials With or Without Spin by English-speaking Patients
Status: COMPLETED
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: News items with spin|OTHER: News items without spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Intraoperative Music on Inflammatory Response in Donor Hepatectomy
Status: RECRUITING
Conditions: Transplantation|Hepatectomy|Music|Stress Response
Interventions: OTHER: music|OTHER: no music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Open-Label Study of Vascazen in Cardiac Rehab Patients With Deficient Blood Omega-3 Fatty Acid Levels
Status: UNKNOWN
Conditions: Dyslipidemia
Interventions: OTHER: VASCAZEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Getting Biased Treatment Study: How Psychotherapy and Antidepressants Change Brain Activity in Chronic Depression
Status: UNKNOWN
Conditions: Chronic Depression
Interventions: DRUG: Duloxetine|BEHAVIORAL: Cognitive Behavioural Analysis System of Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Internet-Delivered Psychological Treatment for Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Cancer Survivors|Anxiety|Depression
Interventions: BEHAVIORAL: Support and information|BEHAVIORAL: Behavioral activation|BEHAVIORAL: Systematic exposure with mindfulness training|BEHAVIORAL: Promotion of health behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synergy Between Stent and Drugs to Avoid Ischemic Recurrences After Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: clopidogrel treatment after bare metal stent implantation|DRUG: clopidogrel treatment after bare metal stent implantation|DRUG: clopidogrel after zotarolimus-eluting stent implantation|DRUG: clopidogrel after paclitaxel-eluting stent implantation|DRUG: clopidogrel after everolimus-eluting stent implantation|DRUG: clopidogrel after zotarolimus-eluting stent implantation|DRUG: clopidogrel after paclitaxel-eluting stent implantation|DRUG: clopidogrel after everolimus-eluting stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Glucose-fructose Drinks During Training on Lactate Transport
Status: COMPLETED
Conditions: Normal Physiology on Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: Glucose-fructose|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Assess the Efficacy and Safety of YYD601 in NERD Patients
Status: COMPLETED
Conditions: Non-erosive Reflux Disease
Interventions: DRUG: YYD601 20mg|DRUG: Nexium 20mg|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Alcohol Dependence
Status: UNKNOWN
Conditions: Alcohol Dependence
Interventions: COMBINATION_PRODUCT: Transcranial magnetic stimulation and cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective?
Status: UNKNOWN
Conditions: Covid-19, Coronavirus, Angiotensin Converting Enzyme Inhibitors, Influenza, Electronic Health Records, Epidemiology, Comorbidity, Incidence, United Kingdom
Interventions: DRUG: ACE inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FLT-PET/MRI for Early Response Monitoring to Novel Cancer Therapeutic Agents
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: fluorine F 18 fluorothymidine|DEVICE: positron emission tomography|DEVICE: magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects Of Single Doses Of GW784568X On Allergic Rhinitis Symptoms In Male Subjects Whilst In An Environmental Chamber
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: GW784568X|DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Physiological Intermolecular Modification Spectroscopy (PIMS) in Ulcerative Colitis With Golimumab
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DRUG: Golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer
Status: COMPLETED
Conditions: Drug Toxicity|Lung Cancer
Interventions: DRUG: 13-cis retinoic acid|DIETARY_SUPPLEMENT: Tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Outcomes of Selective Dorsal Rhizotomy Among Individuals With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DIAGNOSTIC_TEST: Gait and Motion Analysis|DIAGNOSTIC_TEST: Gross Motor Function Measure (GMFM)|BEHAVIORAL: Surveys
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Idasanutlin in Combination With Obinutuzumab in Relapsed/Refractory (R/R) Follicular Lymphoma (FL) and in Combination With Rituximab in R/R Diffuse Large B-Cell Lymphoma (DLBCL) Participants
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Idasanutlin|DRUG: Obinutuzumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite
Status: UNKNOWN
Conditions: Necrotic Pulp
Interventions: OTHER: curcumin solution|OTHER: sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Application of Rapid Fresh Digital Pathology on the Diagnosis and Biomarker Testing of Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Intraoperative Pathology|3D Pathology|Immunochemistry Staining
Interventions: DIAGNOSTIC_TEST: mesoscale nonlinear optical gigascope|DIAGNOSTIC_TEST: Fluorescence microscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Secreted Phosphoproteins and PiP3 (Phosphoinositolphospat 3) in Sputum
Status: COMPLETED
Conditions: Healthy|Smoking, Cigarette
Interventions: OTHER: Induced sputum procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cross-over Study to Investigate Retinal Function Following Administration of a Single Dose of AZD9056
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD9056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Assess the Safety, Reactogenicity and Immune Response of CureVac's Candidate Rabies mRNA Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Rabipur®|BIOLOGICAL: Rabies mRNA vaccine CV7202 Dose level 1|BIOLOGICAL: Rabies mRNA vaccine CV7202 Dose level 2|BIOLOGICAL: Rabies mRNA vaccine CV7202 Dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surveillance and Follow-up for Latent Tuberculosis Infection and Observation of the Effect of Prophylactic Latent Tuberculosis Treatment in Patients With Severe Chronic Kidney Disease or Receiving Long-term Dialysis
Status: UNKNOWN
Conditions: To Determine the Prevalence of Latent Tuberculosis in Each Group|To Monitor the Occurrence of Active Tuberculosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Two Cycling Off Modes in Pressure Support: Study of Respiratory Mechanics, Breathing Comfort and Asynchrony Patterns
Status: COMPLETED
Conditions: Ventilator Weaning|Respiration, Artificial
Interventions: OTHER: Pulmonary Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Effect of Music and Environmental Noise Isolation on Bronchiolitis Severity in Hospitalized Children: a Randomized Control Trial
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: BEHAVIORAL: Mozart|BEHAVIORAL: Instrumental music|BEHAVIORAL: Silence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring the Efficacy of Duvalizumab Combined With Neoadjuvant Chemotherapy for Ib-IIIb NSCLC by Sequencing of Immune Receptor Repertoire: a Prospective, One Arm Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Ib-IIIb NSCLC
Interventions: DRUG: Duvalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent Cancer Telemedicine for Pain Management
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Telemedicine Pain Management Intervention (immediate group)|BEHAVIORAL: Telemedicine Pain Management Intervention (waitlist group, intervention administered following 4-week waitlist period)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of an Onlay Mesh for Prevention of Incisional Hernia After Loop Ileostomy Closure
Status: UNKNOWN
Conditions: Incisional Hernia
Interventions: RADIATION: Control CT|OTHER: Clinical Follow Up|PROCEDURE: Reinforcement with Light Polypropylene Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Standard of care|DRUG: Apremilast|DRUG: Apremilast placebo|DRUG: Lanadelumab|DRUG: Lanadelumab placebo|DRUG: Zilucoplan|DRUG: Zilucoplan placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of CLS2901C in Patients With Osteoarthritis of the Knee
Status: RECRUITING
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: CLS2901C (human [allogeneic] chondrocyte sheets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: mHealth Skill Enhancement Plus Phone CBT for Type 2 Diabetes Distress Medication Nonadherence: Pilot Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: CBT|DEVICE: Smartphone app|OTHER: Standard Diabetes Care at PCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide Added at the End of Sevoflurane Anesthesia and Recovery
Status: COMPLETED
Conditions: Elective Surgical Procedures|Laparoscopy|Laparotomy|Anesthesia, General|Anesthesia Recovery Period
Interventions: DRUG: Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial: 68Ga-NODAGA-E(c[RGDyK])2 Positron Emission Tomography for Imaging Angiogenesis in Primary and Metastatic Tumor Lesions in Humans
Status: UNKNOWN
Conditions: Neuroendocrine Carcinoma|Breast Cancer|Ovarian Cancer
Interventions: DRUG: Injection of 68Ga-NODAGA-E(c[RGDyK])2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Treatment-resistant Schizophrenia|Side Effect|Lipid Metabolism Disorders|Diabetes|NAFLD|Psychosis
Interventions: DRUG: Aripiprazole|DRUG: Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DP303c Versus Trastuzumab Emtansine in in Patients With HER2-positive Advanced Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: DP303c|DRUG: trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxotere®, Eloxatin® and Xeloda® (TEX) in Combination With Herceptin® as Treatment for HER2 Positive Non-resectable Cancer
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: DRUG: Docetaxel|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transradial Versus Transfemoral Arterial Access in Liver Cancer Embolization: Randomized Trial to Assess Patient Outcomes and Satisfaction (BEST ACCESS Trial).
Status: COMPLETED
Conditions: Hepatic Carcinoma|Chemoembolizaton|Transarterial Embolization
Interventions: PROCEDURE: Transarterial embolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Cognitive Functions in 20 Patients With Type 1 Myotonic Dystrophy With Virtual Reality Approach
Status: WITHDRAWN
Conditions: Myotonic Dystrophy 1
Interventions: DIAGNOSTIC_TEST: Type 1 myotonic dystrophy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Subcutaneous (SC) Darbepoetin Alfa in Subjects With Symptomatic Congestive Heart Failure (CHF) & Anemia
Status: COMPLETED
Conditions: Congestive Heart Failure|Anemia
Interventions: DRUG: Darbepoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Multi-Sectoral Agricultural Intervention to Improve Nutrition, Health, and Developmental Outcomes of HIV-infected and Affected Children in Western Kenya
Status: COMPLETED
Conditions: Child Nutrition, Child Neurobehavioral Development
Interventions: BEHAVIORAL: Multisectoral agriculture and Microfinance Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trans-inguinal Pre-peritoneal Hernioplasty Versus Lichtnestein's Technique in Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Trans-inguinal Pre-peritoneal Hernioplasty|PROCEDURE: Lichtnestein's hernioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EUS Guided ERCP in Bile Duct Stone Removal
Status: COMPLETED
Conditions: Choledocholithiasis
Interventions: PROCEDURE: ERCP without the use of fluoroscopy|PROCEDURE: ERCP with the use of fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2a Study of Human Anti-CD 38 Antibody MOR03087 (MOR202) in Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: MOR03087 phase 1 dose escalation|DRUG: MOR03087|DRUG: Dexamethasone|DRUG: Pomalidomide|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whole Grain Diet on Insulin Sensitivity, Advanced Glycation End Products and Inflammatory Markers in Pre-diabetes
Status: COMPLETED
Conditions: Diabetes|Prediabetes
Interventions: OTHER: Whole grain rice|OTHER: Refined grain rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-1014-6470 (SAD)|DRUG: ACT-1014-6470 (MAD)|DRUG: Placebo (SAD)|DRUG: Placebo (MAD)|DRUG: 14C-ACT-1014-6470 microtracer|DRUG: 14C-ACT-1014-6470 microtracer placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib|OTHER: Tumor biopsy|PROCEDURE: Nephrectomy|OTHER: Biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.
Status: UNKNOWN
Conditions: Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Interventions: OTHER: Chamomile oral cryotherapy|OTHER: Oral cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Status: RECRUITING
Conditions: Graft vs Host Disease
Interventions: DRUG: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolving Methods of Hybrid Exercise-cognition Approach to Promote Health-related Conditions for the Elderly With MCI
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Stroke
Interventions: OTHER: cognitive training|OTHER: physical exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pre-labor Ultrasound as a Visual Biofeedback Device for Maternal Pushing Education
Status: COMPLETED
Conditions: Pregnancy Related|Delivery Complication
Interventions: BEHAVIORAL: Pre-labor ultrasound as a visual biofeedback device for maternal pushing education and pelvic floor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-55308942 in Healthy Male and Female Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-55308942 0.5 mg|DRUG: JNJ-55308942 1.5 mg|DRUG: JNJ-55308942 4 mg|DRUG: JNJ-55308942 12 mg|DRUG: JNJ-55308942 36 mg|DRUG: JNJ-55308942 100 mg|DRUG: JNJ-55308942: Fed State|DRUG: JNJ-55308942: MAD Part|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Performance of the NGPOD® Device in Verifying the Correct Position in the Stomach of the Naso- or Oro- Gastric Tube in Intensive Care.
Status: NOT_YET_RECRUITING
Conditions: Intensive Care|Nutrition
Interventions: DIAGNOSTIC_TEST: pH indication with NGPOD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
Status: COMPLETED
Conditions: Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Interventions: DRUG: DaxibotulinumtoxinA for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Inpatient Cognitive Therapy for the Prevention of Suicide in Military Personnel
Status: COMPLETED
Conditions: Suicide, Attempted
Interventions: BEHAVIORAL: Post Admission Cognitive Therapy (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive and Neurobiological Improvement in ADHD Children by Modification of Dietary Protein
Status: COMPLETED
Conditions: ADD|ADHD
Interventions: DRUG: BP22042013|DIETARY_SUPPLEMENT: Low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DEVICE: hydrous biopolymer with silver ions "Argiform"|DEVICE: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients With CLDN18.2-positive Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Dual-targeting CLDN18.2 and PD-L1 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex Trial
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: ZD6474 (Vandetanib at the dose of 100 mg)|DRUG: Placebo to match ZD6474 (Vandetanib at the dose of 100 mg)|DRUG: Fulvestrant|DRUG: ZD6474 (Vandetanib at the dose of 300 mg)|DRUG: Placebo to match ZD6474 (Vandetanib at the dose of 300 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Adjustable Doses of Extended-release (ER) Paliperidone Compared With Placebo, in Combination With Lithium or Valproate, to Treat Manic and Mixed Episodes in Patients With Bipolar I Disorder
Status: COMPLETED
Conditions: Affective Psychosis, Bipolar|Bipolar Disorder|Mania
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2428757|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mass Drug Administration for Reducing Seasonal Malaria Transmission in Zanzibar
Status: COMPLETED
Conditions: Malaria|Plasmodium Infections
Interventions: DRUG: MDA with DHAp and SLD Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EUS Biliary Drainage vs. ERCP
Status: COMPLETED
Conditions: Biliary Obstruction
Interventions: PROCEDURE: EUS-BD with LAMS|PROCEDURE: ERCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Ultrasound Guided External Oblique Intercostal Plane (EOIP) Block and Erector Spinae Plane (ESP) Block for Postoperative Analgesia in Upper Abdominal Surgeries
Status: NOT_YET_RECRUITING
Conditions: Block
Interventions: PROCEDURE: external oblique intercostal plane block|PROCEDURE: erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Tooth Extraction in Patients With Atrial Fibrillation in Use of New Oral Anticoagulants
Status: COMPLETED
Conditions: Atrial Fibrillation|Periodontal Disease|Hemorrhage
Interventions: DRUG: Rivaroxaban|DRUG: Dabigatran and Apixaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-interventional Study on Oral Contraception Not Containing Ethinylestradiol (EE) to Assess Continuation Rates and Satisfaction
Status: COMPLETED
Conditions: Contraceptives, Oral
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027)|DRUG: Progestin Only Pills
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodialysis.-Induced Hypotension Therapy for End Stage Kidney Disease
Status: RECRUITING
Conditions: Hemodialysis Complication|Hypotension of Hemodialysis
Interventions: DRUG: Lanadelumab Injection [Takhzyro]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Tiragolumab|DRUG: Tobemstomig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.
Status: UNKNOWN
Conditions: Corona Virus Infection|ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2|Oxygen Deficiency
Interventions: DEVICE: Oxygen theraphy with high flow nasal cannule|DEVICE: Oxygen theraphy with mask with reservoir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatment
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: arasertaconazole nitrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy
Status: RECRUITING
Conditions: Dyspareunia|Pelvic Pain|Sexual Dysfunction|Radiation Toxicity
Interventions: BEHAVIORAL: Pelvic health therapy|DEVICE: Dilator feasability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimized Antithrombotic Therapy of Acute Myocardial Infarction With Left Ventricular Mural Thrombus
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Left Ventricular Thrombus
Interventions: DRUG: Combination of antiplatelet drugs and anticoagulants for at least one month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ginseng on Stress, Emotional and Cognitive Processing
Status: COMPLETED
Conditions: Stress
Interventions: DIETARY_SUPPLEMENT: Dietary supplement group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Expanded Noninvasive Genomic Medical Assessment: The Enigma Study
Status: COMPLETED
Conditions: Down Syndrome|Edwards Syndrome|Patau Syndrome|Klinefelter Syndrome|Turner Syndrome|DiGeorge Syndrome|Chromosome Deletion|Aneuploidy
Interventions: OTHER: Blood sampling for Laboratory Developed Test (LDT) analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reliability of a Top Mount Actuation Indicator With Levalbuterol MDI in Adult and Pediatric Subjects With Asthma or COPD
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Levalbuterol HFA MDI with top mounted actuation indicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Alcohol Dependency in Patients With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder|Alcohol Dependence
Interventions: DRUG: Quetiapine fumarate|DRUG: lithium|DRUG: divalproex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons
Status: COMPLETED
Conditions: Tuberculosis|Latent Tuberculosis Infection|HIV Infections
Interventions: DRUG: isoniazid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Half Swaddle and Kangaroo Care in Preterm on Breastfeeding, Infant Attachment, Sleep Quality and Depression of Mothers
Status: COMPLETED
Conditions: Kangaroo Care
Interventions: OTHER: Half swaddle|OTHER: Kangaroo care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotc Lactobacillus Crispatus-M247 (Crispact®) Supplementation in the Sterilization of High-risk Human Papilloma (HPV-HR) Viruses
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus Infection
Interventions: DIETARY_SUPPLEMENT: Crispact®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2b Evaluation of Daclatasvir/Sofosbuvir in Non-Cirrhotic Treatment Naive Subjects With Genotype 1, 2, 3 and 4 Chronic Hepatitis C Virus Coinfected With Human Immunodeficiency Virus (HIV-1)
Status: WITHDRAWN
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of ALLO-ASC-DFU in the Patients With Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: ALLO-ASC-DFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2940680 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: LY2940680 Capsule(s) (Reference)|DRUG: LY2940680 Tablet (Test)|DRUG: Lansoprazole|DRUG: Placebo Capsule(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Fermented Rye Bran Products on Helicobacter Pylori (HP) Infection and Metabolic Risk Factors
Status: ACTIVE_NOT_RECRUITING
Conditions: H. Pylori Infections|Non-communicable Diseases
Interventions: DIETARY_SUPPLEMENT: intake of food product with a patented fermented rye bran|DIETARY_SUPPLEMENT: intake of food product with common refined wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Status: NOT_YET_RECRUITING
Conditions: Mastication Disorder|Fatigue|Temporomandibular Disorder|Orofacial Pain|Chewing Problem
Interventions: DIAGNOSTIC_TEST: Functional 6-minute mastication test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-Thymocyte Globulin and Etanercept in Treating Patients With Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin Combination as 1st Line Treatment in Ovarian Carcinomas
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Fekry Oral Intubating Airway and Ovassapian Fibreoptic Intubating Airway for Fibreoptic Orotracheal Intubation
Status: COMPLETED
Conditions: Ovassapian VS Fekry Airways
Interventions: DEVICE: Ovassapian Fibreoptic Intubating Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Virtual Reality Decreases Child Anxiety and Pain as Well as Caregiver Anxiety and Pain Perception During Orthopaedic Clinic Office Procedures
Status: TERMINATED
Conditions: Anxiety|Pain
Interventions: BEHAVIORAL: Control|DEVICE: Virtual Reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physical and Mental Practice for Bimanual Coordination Rehabilitation
Status: COMPLETED
Conditions: Traumatic Brain Injury|Weakness, Muscle|Coordination Impairment
Interventions: BEHAVIORAL: Hand coordination and mental practice|BEHAVIORAL: Hand coordination and action observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AGV Implantation With Ologen in Pediatric Glaucomas
Status: UNKNOWN
Conditions: Glaucoma
Interventions: PROCEDURE: Ahmed Glaucoma Valve Implantation in secondary pediatric glaucomas.|PROCEDURE: Ahmed Glaucoma Valve Implantation with Ologen augmentation in secondary pediatric glaucomas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Gemcitabine Followed by Radiation Therapy in the Management of Mixed Mullerian Tumors of the Uterus
Status: COMPLETED
Conditions: Mixed Mullerian Tumors of the Uterus
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Interstitial Lymphography in Early Stage Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Lung Cancer Non-Small Cell Cancer (NSCLC)|Lung Cancer Small Cell Lung Cancer (SCLC)|Mesothelioma
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|RADIATION: Computed Tomography (CT)|DEVICE: Cyberknife|DEVICE: Trilogy|DEVICE: True Beam|DRUG: Iohexol|DRUG: Iodixanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The DANE-HEART Trial - Computed Tomography Coronary Angiography for Primary Prevention
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Atherosclerosis and Other Heart Disease|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Primary preventive treatment guided by CTCA|OTHER: Cardiovascular risk Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Efficacy of S-1226 in Post-COVID-19 Subjects With Persistent Respiratory Symptoms.
Status: UNKNOWN
Conditions: Post Acute COVID-19 Syndrome|Long COVID|COVID-19 Respiratory Infection
Interventions: DRUG: S-1226 (8%)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Vasoconstriction Study With LEO 90100
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100 Aerosol, foam|DRUG: Betamethasone dipropionate in LEO 90100 Aerosol, foam, vehicle|DRUG: LEO 90100 Aerosol, foam, vehicle|DRUG: Daivobet® ointment|DRUG: Dermovate® cream|DRUG: Synalar® ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Community Health Through Patient Navigation, Advocacy and Social Support
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Chronic Kidney Diseases|Ischemic Heart Disease|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma
Interventions: BEHAVIORAL: ENCOMPASS Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Hinge Flap to Reinforce Buccal Advancement Flap
Status: RECRUITING
Conditions: Oroantral Fistula
Interventions: PROCEDURE: A hinge flap will be performed to reinforce the buccal advancement flap to close the oroantral fistula at the most posterior area of the maxilla|PROCEDURE: An anteriorly based palatal flap will be performed to close the oroantral fistula at the most posterior area of the maxilla
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of High Dietary Fiber on Microbiome and Vaccine Responses
Status: RECRUITING
Conditions: Influenza
Interventions: DIETARY_SUPPLEMENT: High-Fiber Diet (HFD)|DIETARY_SUPPLEMENT: Prebiotic Food-Enriched Diet (PreFED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Status: ENROLLING_BY_INVITATION
Conditions: PAH|Pulmonary Hypertension|Pulmonary Arterial Hypertension|Hypertension|Connective Tissue Diseases|Familial Primary Pulmonary Hypertension|Vascular Diseases|Cardiovascular Diseases|Hypertension, Pulmonary|Lung Diseases|Respiratory Tract Disease
Interventions: DRUG: Ralinepag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib in Patients With Advanced Non-squamous and Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: apatinib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate B4T2-001 CAR T Cells in the Treatment of Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: B4T2-001 Autologous CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT