pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Saracatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: saracatinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga for Youth With IBD: a Pilot Feasibility Study
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Yoga|Adolescents|Crohn Disease|Ulcerative Colitis
Interventions: BEHAVIORAL: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation
Status: RECRUITING
Conditions: Parathyroid Dysfunction|Adenoma
Interventions: DRUG: Indocyanine green|DEVICE: SPY Portable Handheld Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.
Status: TERMINATED
Conditions: Non-ST Elevation Acute Coronary Syndrome
Interventions: DRUG: ticagrelor|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct and Reversed Dorsal Digital Island Flaps: A Review of 65 Cases
Status: COMPLETED
Conditions: Soft Tissue Reconstruction|Sensory Restoration
Interventions: PROCEDURE: Direct and reversed dorsal digital island flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propolis-based Product (FARINGEL PLUS) for Oral Mucositis in Palliative Care
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: COMBINATION_PRODUCT: Faringel plus and oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beverage Hydration Index: Assessment of Four Rehydration Solutions
Status: RECRUITING
Conditions: Hydration
Interventions: DIETARY_SUPPLEMENT: Multiplier|DIETARY_SUPPLEMENT: Sugar Free|DIETARY_SUPPLEMENT: Sugar Free with Amino Acids|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Transgenic Lymphocyte Immunization Vaccine in Subjects With Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: Transgenic Lymphocyte Immunization Vaccine (TLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-CEOP-90/R-CEOP-70 Versus R-CHOP-50 in the Treatment of Diffuse Large B-cell Lymphoma and Follicular Lymphoma Grade 3B
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma|Follicular Lymphoma Grade 3B
Interventions: DRUG: R-CEOP-70|DRUG: R-CEOP-90|DRUG: R-CHOP-50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: OTHER: placebo|DRUG: defined green tea catechin extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 18F-FLUC-CEST PET/MR in Patients With Brain Mets
Status: RECRUITING
Conditions: Brain Metastasis|Radiation Therapy|Immunotherapy, Active
Interventions: RADIATION: F-Fluciclovine radiotracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combining Active Living Programme (ALP) With Home-Use Wearable Technical Aids (WTA)
Status: COMPLETED
Conditions: Stroke|Foot Drop (Acquired)
Interventions: DEVICE: Active Living programme and wearable technical aids|DEVICE: Wearable technical aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients
Status: WITHDRAWN
Conditions: Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU
Interventions: OTHER: Sedation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules
Status: RECRUITING
Conditions: Cigarette Smoker|Current Smoker|Former Smoker|Multiple Pulmonary Nodules|Pulmonary Nodule
Interventions: PROCEDURE: Computed Tomography|DRUG: Fludeoxyglucose F-18|DRUG: Fluorine F 18 L-glutamate Derivative BAY94-9392|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Computer-Assisted Navigation for Intramedullary Nail Fixation of Intertrochanteric Femur Fractures
Status: COMPLETED
Conditions: Intertrochanteric Femur Fractures
Interventions: DEVICE: Stryker ADAPT computer-assisted navigation|DEVICE: Conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Bioequivalence Study of Efgartigimod PH20 SC Administered Via a Prefilled Syringe Versus a Vial+Syringe Presentation in Healthy Adults
Status: COMPLETED
Conditions: Bioequivalence
Interventions: BIOLOGICAL: efgartigimod PH20 SC as a prefilled syringe presentation|BIOLOGICAL: efgartigimod PH20 SC as a vial + syringe presentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lycopene vs Minocycline Hydrochloride as Adjunctive to Periodontal Treatment
Status: UNKNOWN
Conditions: Periodontal Pocket
Interventions: DRUG: Lycopene|DRUG: Minocycline HCl 1mg Oral Powder|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer
Status: RECRUITING
Conditions: Quality of Life|Parenthood Status
Interventions: OTHER: Roadmap to Parenthood|OTHER: Informational Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GI Fluids Collection for an Ex-Vivo Development of Ingestible Capsule Devices With Real Time Biosensors
Status: COMPLETED
Conditions: Chronic Inflammatory Small Bowel Disease
Interventions: PROCEDURE: Endoscopy procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness and Safety of CELSTAT for Hemostasis in Intraoperative Tissue Bleeding
Status: COMPLETED
Conditions: Bleeding Active
Interventions: DEVICE: CELSTAT|DEVICE: Surgicel Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NHFOV as Primary Support in Very Preterm Infants With RDS
Status: RECRUITING
Conditions: to Test the Hypothesis That NHFOV is More Effective Than nCPAP in the Treatment of Respiratory Distress Syndrome (RDS) in Verypreterm Neonates
Interventions: PROCEDURE: infants receive primary non-invasive respiratory support by mean of nCPAP|PROCEDURE: infants receive primary non-invasive respiratory support by mean of NHFOV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
Status: NOT_YET_RECRUITING
Conditions: Fetal Conditions|Maternal; Procedure|Pregnancy Related|Twin to Twin Transfusion Syndrome|In Utero Procedure Affecting Fetus or Newborn|Chorion; Abnormal|Twin Reversal Arterial Perfusion Syndrome|Twin Monochorionic Monoamniotic Placenta|Chorioangioma|Vasa Previa
Interventions: DEVICE: Karl Storz Curved Scope|DEVICE: Karl Storz Straight Scope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and Omeprazole
Status: COMPLETED
Conditions: Prostate Cancer Patients
Interventions: DRUG: Midazolam, Warfarin, Omeprazole, VitaminK1 and SHR3680
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Lumbar Proprioception Training on Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: OTHER: lumbar proprioception training|OTHER: Hot packs|OTHER: Pelvic rocking exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT
Status: COMPLETED
Conditions: Cholestasis|Primary Sclerosing Cholangitis|Primary Biliary Cirrhosis
Interventions: DRUG: 11C-CSar|DRUG: ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma
Status: RECRUITING
Conditions: Malignant Peritoneal Mesothelioma|Peritoneal Mesothelioma|Mesothelioma|Mesothelioma, Malignant|Malignant Mesothelioma
Interventions: DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Investigation of Stem Cells in Stroke Phase II Efficacy
Status: COMPLETED
Conditions: Ischaemic Stroke|Cerebral Infarction|Hemiparesis|Arm Paralysis
Interventions: BIOLOGICAL: CTX DP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption
Status: COMPLETED
Conditions: Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption
Interventions: DRUG: bolus of intravenous ketamine|DRUG: continuous infusion of intravenous ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Cardiovascular Effects.
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Diabetes Mellitus, Type 2|Ketonemia
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL)
Status: COMPLETED
Conditions: Adenovirus Infection|EBV Infection
Interventions: BIOLOGICAL: Trivirus Specific CTLs for EBV, CMV and Adenovirus Infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP
Status: TERMINATED
Conditions: Morbid Obesity|Gastroesophageal Reflux Disease|Vomiting
Interventions: PROCEDURE: Sham Comparator: no ring|PROCEDURE: RYGBP-RING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation With Special Waveform for Upper Extremity Rehabilitation for Patients With Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: tCES|DEVICE: Sham tCES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Er:YAG Laser|OTHER: Carbon Fiber Curette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery
Status: RECRUITING
Conditions: Obesity|Obesity, Morbid
Interventions: PROCEDURE: Standard duodenal switch|PROCEDURE: Single-anastomosis duodenal switch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation for Management of Temporomandibular Disorder Pain
Status: RECRUITING
Conditions: Pain Related to TMD
Interventions: DEVICE: THOR® laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Treatment in Calcified Coronary Disease
Interventions: DEVICE: Intravascular Lithotripsy|DEVICE: Cutting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meniscal INfiltration of Corticosteroid Guided With Ultra Sonography
Status: NOT_YET_RECRUITING
Conditions: Meniscus Lesion
Interventions: DRUG: ultrasound-guided betamethasone infiltration of the meniscal wall|DRUG: ultrasound-guided isotonic saline (placebo) infiltration of the meniscal wall
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emotion, Mood and Executive Function in Parkinson's Disease (PD)
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of ABX-EGF in Patients With Renal Cancer, Part 2
Status: COMPLETED
Conditions: Advanced Renal Cell Carcinoma
Interventions: DRUG: Panitumumab (ABX-EGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Detection of Circulating Tumor Cells (CTCs) in Patients With Prostatic Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Status: COMPLETED
Conditions: Neoplastic Cells, Circulating
Interventions: OTHER: Flow cytometry (FCM)|OTHER: RT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of a Single Dose of Monovalent High-dose Inactivated Poliovirus Type 2 Vaccine (m-IPV2 HD) in Infants Early in Life
Status: COMPLETED
Conditions: Polio
Interventions: BIOLOGICAL: b-OPV|BIOLOGICAL: m-OPV2|BIOLOGICAL: m-IPV HD|BIOLOGICAL: t-IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Infant Formula and follow-on Formula Containing Bio-active Ingredients on Growth, Tolerance and Infections
Status: RECRUITING
Conditions: Growth|Infections
Interventions: OTHER: cows milk infant formula and follow-on formula with bioactive ingredients|OTHER: standard cows milk infant formula and follow-on formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Efficacy and Safety Study of Intravenous Palonosetron Administered as an Infusion and as a Bolus for the Prevention of Nausea and Vomiting
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Palonosetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery
Status: COMPLETED
Conditions: Upper Extremity|Orthopedic Surgery|Trauma|Forearm Injuries|Nerve Block
Interventions: DRUG: Midazolam|DRUG: Ropivacaine|DRUG: Fentanyl|PROCEDURE: General anesthesia|PROCEDURE: Axillary brachial plexus nerve block|PROCEDURE: Infraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diazepam at the Active Phase of Labor
Status: UNKNOWN
Conditions: Pain|Prolonged Labour
Interventions: DRUG: normal saline/diazepam at the active phase of labor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Cervarix®
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever|Human Papillomavirus Disease
Interventions: BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: CYD Dengue Vaccine|BIOLOGICAL: Human Papillomavirus Bivalent [Types 16 and 18] Vaccine, Recombinant|BIOLOGICAL: Human Papillomavirus Bivalent [Types 16 and 18] Vaccine, Recombinant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EVITA Study - Epstein-Barr Virus Infection moniToring in renAl Transplant Recipients
Status: RECRUITING
Conditions: EBV Infection|EBV Viremia|Epstein-Barr Virus Associated Lymphoproliferative Disorder|Post-transplant Lymphoproliferative Disorder
Interventions: DIAGNOSTIC_TEST: EBV DNA in whole blood and plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Juvista (Avotermin) Following Removal of Ear Lobe Keloid Scars
Status: COMPLETED
Conditions: Keloid
Interventions: DRUG: Avotermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water Injection Colonoscopy vs Air Insufflation Colonoscopy in Training the Beginners
Status: UNKNOWN
Conditions: Colon Disease|Rectal Disease|Pain
Interventions: OTHER: Air insufflation|OTHER: Water injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiofrequency For Chronic Knee Pain Post-Arthroplasty
Status: COMPLETED
Conditions: Chronic Knee Pain|Osteoarthritis, Knee
Interventions: PROCEDURE: Nerve Block with Radiofrequency Ablation|PROCEDURE: Nerve Block with Sham Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential
Status: COMPLETED
Conditions: Drug Interactions|Neoplasms
Interventions: DRUG: GSK525762 Besylate Tablets|DRUG: Itraconazole 200 mg|DRUG: Rifampicin 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactoferrin on Polio Seroconversion
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: DIETARY_SUPPLEMENT: Bovine Lactoferrin|OTHER: Placebo Glucon D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fructose-Induced Palmitate Synthesis in Overweight Subjects
Status: COMPLETED
Conditions: Elevated Triglycerides|Diabetes|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Fructose|DIETARY_SUPPLEMENT: Fructose and Glucose|DIETARY_SUPPLEMENT: Fructose and Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Protectivity and Safety of DTP/HB/Hib (Bio Farma) Vaccines in Infants, Batch Consistency, Multi Center Trial
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: DTP/HB/Hib Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation
Status: RECRUITING
Conditions: Heart Valvular Disease|Coronary Arteriosclerosis|One-lung Ventilation
Interventions: PROCEDURE: Minimally Invasive Cardiac Surgery (airway management with double-lumen tube)|PROCEDURE: Minimally Invasive Cardiac Surgery (airway management with endobronchial blocker)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal Adenocarcinoma
Status: RECRUITING
Conditions: Submucosal Esophageal Adenocarcinoma|Barrett Esophagus|High-risk Mucosal Esophageal Adenocarcinoma
Interventions: PROCEDURE: Endoscopic follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Acute Kidney Injury and Improving Outcome in Critically Ill Patients Utilising Risk Prediction Score
Status: COMPLETED
Conditions: Acute Kidney Injury|Critical Illness
Interventions: OTHER: Measures to prevent AKI among critically ill patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Immunogenicity of MVA.HTI and ChAdOx1.HTI With Vesatolimod in HIV-1 Positive Patients
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BIOLOGICAL: ChAdOx1.HTI|BIOLOGICAL: MVA.HTI|DRUG: GS-9620|BIOLOGICAL: Placebo|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Tiotropium Inhalation Capsules (Spiriva) on Exercise Tolerance in COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Multiple Doses of VIT-2763 in Adults With Transfusion-dependent Beta-thalassemia
Status: WITHDRAWN
Conditions: Beta-Thalassemia
Interventions: DRUG: VIT-2763 60 mg QD|DRUG: VIT-2763 60 mg BID|DRUG: VIT-2763 120 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD
Status: COMPLETED
Conditions: Cognitive Behavioral Therapy|Autism Spectrum Disorder|Anxiety Disorder|Obsessive-Compulsive Disorder|Social Anxiety Disorder|Generalized Anxiety Disorder|Specific Phobia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy-Email (iCBT-E)|BEHAVIORAL: Cognitive Behavioral Therapy-Email and Videoconferencing (iCBT-EV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
Status: COMPLETED
Conditions: Atrophic Acne Scar
Interventions: DEVICE: ELAPR002f|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Relative Bioavailability and Food-Effect of HA121-28 Tablet B in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: HA121-28 tablet B|DRUG: HA121-28 tablet A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Therapeutic Effect of Catgut Embedding in Obesity
Status: UNKNOWN
Conditions: Obese Women
Interventions: DEVICE: Catgut embedding group|DEVICE: sham catgut embedding group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined STN/SNr-DBS for the Treatment of Refractory Gait Disorders in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: deep brain stimulation (ACTIVA PC, Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: END-1: First Line Chemotherapy for Advanced or Recurrent Endometrial Carcinoma With Carboplatin and Liposomal Doxorubicin
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: liposomal doxorubicin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Demonstrate Equivalent Immunogenicity of CAIV-T and FLUMIST in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CAIV-T|BIOLOGICAL: CAIVT|BIOLOGICAL: FluMist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma
Status: RECRUITING
Conditions: Basal Cell Carcinoma|Superficial Basal Cell Carcinoma|Nodular Basal Cell Carcinoma
Interventions: DEVICE: 1064 nm long-pulse Nd:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Pembrolizumab Dose Optimisation in Solid Tumours With CURATE.AI Platform and Sequential ctDNA Measurements
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DEVICE: CURATE.AI|DRUG: Nivolumab, Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Hypoglycaemia in Congenital Adrenal Insufficiency
Status: COMPLETED
Conditions: Adrenal Insufficiency, Congenital
Interventions: OTHER: Continuous blood glucose measurement|OTHER: Measurement of capillary blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sciatic Perineural Versus Stump Catheter for Below Knee Amputation
Status: COMPLETED
Conditions: Ischemia|Phantom Limb Pain|Vascular Disease|Chronic Pain
Interventions: PROCEDURE: Sciatic catheter|PROCEDURE: Stump catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: BIOLOGICAL: Recombinant human antithrombin (ATryn)|OTHER: Normal Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Hyperthermia Combined With Chemotherapy in Treating Patients With Metastatic Breast, Ovarian, Endometrial, or Cervical Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Cervical Cancer|Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: fluorouracil|DRUG: pegylated liposomal doxorubicin hydrochloride|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Role That Peroral Endoscopic Myotomy (POEM) Could Play in the Treatment of Achalasia
Status: COMPLETED
Conditions: Achalasia
Interventions: PROCEDURE: Peroral Endoscopic Myotomy a less invasive treatment for Achalasia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lifestyle-modification Induced Weight Loss on Sexual and Urinary Function, and Quality of Life in Obese Men
Status: COMPLETED
Conditions: Sexual Dysfunction|Endothelial Dysfunction|Quality of Life|Inflammation
Interventions: BEHAVIORAL: Exercise and diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery
Status: UNKNOWN
Conditions: Periodontal Pocket|Impacted Third Molar Tooth|Impacted Teeth With Abnormal Position
Interventions: PROCEDURE: Impacted third molar surgery|PROCEDURE: Application of mineralised plasmatic matrix|PROCEDURE: Application of β-tricalcium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fusion Protein Cytokine Therapy After Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: BIOLOGICAL: DI-Leu16-IL2 immunocytokine|BIOLOGICAL: rituximab|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: pharmacological study|OTHER: laboratory biomarker analysis|OTHER: enzyme-linked immunosorbent assay|GENETIC: reverse transcriptase-polymerase chain reaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEACON Suicide Prevention in Men Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Intentional Self-Harm|Suicide
Interventions: COMBINATION_PRODUCT: BEACON + Problem Solving Therapy|BEHAVIORAL: Problem-Solving Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of the Immunogenicity and Safety of CVXGA Intranasal COVID Vaccine in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: CVXGA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-center Exploratory Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of a BCMA-targeted Universal LCAR-BCX Cells in Patients With Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: LCAR-BCX cells product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Safety and Efficacy of Olverembatinib Combined With APG-2575 in Children With Relapsed/Refractory Ph + ALL
Status: RECRUITING
Conditions: Lymphoblastic Leukemia, Acute, Childhood|Leukemia, Lymphoblastic, Acute, Philadelphia-Positive|Relapsed Leukemia|Refractory Leukemia
Interventions: DRUG: Olverembatinib, APG-2575, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Compression Neuropathy
Interventions: DRUG: Acetyl-l-carnitine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of ANX005 and IVIG in Subjects With Guillain Barré Syndrome (GBS)
Status: COMPLETED
Conditions: Guillain-Barré Syndrome
Interventions: DRUG: ANX005|DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-Market Study of Transfacet Lumbar Spine Fixation and Fusion Utilizing the PERPOS™ PLS System
Status: WITHDRAWN
Conditions: Lumbar Facet Disease
Interventions: DEVICE: PERPOS™ PLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elucidation of the Mechanisms and Effects of Certain Anesthetic Interventions on Digestive Cancer Patients Subjected to Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Lidocaine 1% Injectable Solution|BIOLOGICAL: Blood extraction|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine
Status: COMPLETED
Conditions: Emotions
Interventions: DRUG: Lamotrigine|DRUG: Ketamine|DRUG: Placebo Pretreatment|DRUG: Placebo Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Factorial Trial of an Integrated Lifestyle Intervention
Status: RECRUITING
Conditions: Physical Inactivity|Overweight and Obesity
Interventions: BEHAVIORAL: Prevent T2|BEHAVIORAL: Move group-based classes|BEHAVIORAL: Fitness Membership|BEHAVIORAL: Mental Imagery|BEHAVIORAL: Move 1:1 Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Physiology of Targeted Theta-burst Neuromodulation
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: theta-burst TMS|DEVICE: sham theta-burst TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects a Honey Based Syrup on Blood Parameters in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: honey based (HB) syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doxorubicin and Paclitaxel in Treating Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Difference in Subclavian Vein Catheterization Between Supine and Lateral Tilt Position - Stage I
Status: UNKNOWN
Conditions: Catheterization|Posture
Interventions: PROCEDURE: Ipsilateral tilt|PROCEDURE: Contralateral tilt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study About How TAK-881 is Processed by the Body and Side Effects in People With Primary Immunodeficiency Diseases
Status: RECRUITING
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: TAK-881|BIOLOGICAL: HYQVIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Biphasic Insulin Aspart 30 Treatment Regimens in Subjects With Type 2 Diabetes Not Achieving HbA1c Treatment Targets on OADs Alone
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30|DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Metformin and Metformin + Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: RAMP 200 / RAMP Cardiovascular Tests at the Point-of-Care
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Heart Failure|Congestive Heart Failure
Interventions: DEVICE: RAMP 200|DEVICE: RAMP Reader
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HPV Testing In Polish POpulation-based Cervical Cancer Screening Program.
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Offering an alternative cervical cancer screening method - hrHPV molecular testing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomised Control Trial of an Intervention to Promote Emotion Regulation Strategies in University Students
Status: UNKNOWN
Conditions: Anxiety|Emotion Regulation
Interventions: BEHAVIORAL: Purrble intervention|BEHAVIORAL: Single Session Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Alirocumab (SAR236553/REGN727) Administered on Top of Ezetimibe or Fenofibrate on Lipid Profiles in Healthy Subjects
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Ezetimibe|DRUG: Ezetimibe Placebo|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Muscle Function and Pelvic Stability While Walking in Patients With Symptomatic Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Symptomatic Lumbar Spinal Stenosis|Lumbar Spinal Stenosis
Interventions: OTHER: Oswestry Disability Index (ODI) questionnaire|DIAGNOSTIC_TEST: self-paced walking test (SPWT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings ("CDE-EHR-PC" Study), Phase 1
Status: COMPLETED
Conditions: Addiction
Interventions: BEHAVIORAL: Interviews with Stakeholders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction
Status: COMPLETED
Conditions: Corneal Edema
Interventions: DRUG: HCEC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial of Hyperosmotlar Saline for Rotator Cuff Repair Irrigation Solution
Status: UNKNOWN
Conditions: Arthroscopic Shoulder Surgery|Rotator Cuff Tear
Interventions: DRUG: Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) and Pancreatic Function Following Surgery
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Synthetic Human Secretin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: NIV Reduces CBF in COPD Patients Without Cognitive Function
Status: COMPLETED
Conditions: COPD|Non-invasive Ventilation|Cognitive Impairment|Cerebral Blood Flow
Interventions: OTHER: Non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Cerebral Oxygenation Results in Premature Infant
Status: COMPLETED
Conditions: Cerebral Oxygenation|Premature|Kangaroo Care|Facilitated Tucking
Interventions: BEHAVIORAL: Kangaroo care|BEHAVIORAL: Facilitated Tucking Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sitaxsentan alone|DRUG: Sitaxsentan|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Postprandial Exercise on Glycaemia and Metabolism in People With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Postprandial exercise of different modalities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.010: A Study of Gemcitabine and Nab-paclitaxel With or Without NPC-1C to Treat Patients With Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer, Adult
Interventions: DRUG: Gemcitabine|DRUG: nab-paclitaxel|DRUG: NPC-1C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT