pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparison of CPT Versus ART Versus WL
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy (CPT)|BEHAVIORAL: Accelerated Resolution Therapy (ART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Novel Dual Renin Angiotensin Aldosterone System (RAAS) Blockade; Valsartan/Aliskiren in African American Patients With Hypertension and the Metabolic Syndrome
Status: WITHDRAWN
Conditions: Hypertension|Metabolic Syndrome
Interventions: DRUG: Aliskerin/Valsartan and Rampiril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Pulsed Radiofrequency With Steroids Injection Versus Intra-articular Steroids Injection in Chronic Sacroiliac Joint Arthritis
Status: COMPLETED
Conditions: Pain Management
Interventions: DRUG: intraarticular radiofrequency + intraarticular methylprednisolone|DRUG: intraarticular methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Two-step Radioimmunotherapy Clinical Study in Medullary Thyroid Carcinoma
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: bispecific antibody and di-DTPA-131I
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Vitrectomy With Silicone Oil or SF6 for Rhegmatogenous Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment|Primary Vitrectomy
Interventions: PROCEDURE: Pars plana vitrectomy with silicone oil|PROCEDURE: Pars plana vitrectomy with SF6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Gonorrhea|Chlamydial Infections|Genital Herpes
Interventions: DRUG: PRO 2000/5|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of TS-142 in Healthy Participants (Repeated Doses)
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Placebo|DRUG: TS-142, 10 mg|DRUG: TS-142, 20 mg|DRUG: TS-142, 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: BIOLOGICAL: Patient-derived CD22-specific CAR T-cells also expressing an EGFRt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 or mNF2 Gene Mutations
Status: RECRUITING
Conditions: Solid Tumor, Adult|Mesothelioma
Interventions: DRUG: VT3989
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Definitive Radiochemotherapy Plus/Minus Cetuximab in Unresectable Locally Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Cetuximab|DRUG: Cisplatin, 5-FU|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Safety and Efficacy Study of Inactivated EV 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants
Status: COMPLETED
Conditions: The Study Focused on the Safety of Inactivated EV71 Vaccine (Human Diploid Cell) Against Hand, Foot and Mouth Disease in Chinese Children and Infants
Interventions: BIOLOGICAL: 160Eu/0.5ml in infants (6-11 months old)|BIOLOGICAL: 320Eu/0.5ml in infants (6-11 months old)|BIOLOGICAL: 640Eu/0.5ml in infants (6-11 months old)|BIOLOGICAL: 1280Eu/0.5ml (without adjuvant) in infants (6-11 months old)|BIOLOGICAL: 0Eu/0.5ml in infants (6-11 months old)|BIOLOGICAL: 160Eu/0.5ml in infants (12-23 months old)|BIOLOGICAL: 320Eu/0.5ml in infants (12-23 months old)|BIOLOGICAL: 640Eu/0.5ml in infants (12-23 months old)|BIOLOGICAL: 1280Eu/0.5ml (without adjuvant) in infants (12-23 months old)|BIOLOGICAL: 0Eu/0.5ml in infants (12-23 months old)|BIOLOGICAL: 160Eu/0.5ml in children (24 months-5 years old)|BIOLOGICAL: 320Eu/0.5ml in children (24 months-5 years old)|BIOLOGICAL: 640Eu/0.5ml in children (24 months-5 years old)|BIOLOGICAL: 1280Eu/0.5ml (without adjuvant) in children (24 months-5 years old)|BIOLOGICAL: 0Eu/0.5ml in children (24 months-5 years old)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine + Bupivacaine vs. Bupivacaine Alone on Opioid Use After Elective c/Section
Status: WITHDRAWN
Conditions: Postoperative Pain|Cesarean Section
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.
Status: COMPLETED
Conditions: Acute-On-Chronic Liver Failure
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses
Status: COMPLETED
Conditions: Keratitis
Interventions: DEVICE: B+L Biotrue MPS and B+L PureVision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Avoidable Hospitalizations/ Emergency Department Visits- Systematic Review and Meta-synthesis of Qualitative Research
Status: UNKNOWN
Conditions: Diabetes|Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma|Hypertension|Urinary Tract Infections|Pneumonia, Bacterial
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Transcranial Direct Current Stimulation (tDCS)
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: Eldith Company - direct current stimulator|DEVICE: Eldith Company - direct current stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Parathyroid Hormone (PTH) on Osseous Cavity
Status: COMPLETED
Conditions: Bone Loss|Periodontitis
Interventions: PROCEDURE: Periodontal surgery|DRUG: FORTEO|DRUG: Placebo|DIETARY_SUPPLEMENT: Vitamin D and Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Role of Dutasteride in Treatment of Chronic Prostatitis
Status: COMPLETED
Conditions: Dutasteride|Category IIIB Chronic Prostatitis
Interventions: DRUG: Dutasteride 0.5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Insulin Aspart With Fast-acting Insulin Human in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin aspart|DRUG: insulin human|DRUG: insulin aspart|DRUG: insulin human
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Bias Modification Training in Adolescents Who Have Experienced Adversity
Status: COMPLETED
Conditions: Child Abuse|Child Neglect|Victimization
Interventions: BEHAVIORAL: Cognitive bias modification training|BEHAVIORAL: Control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DRUG: Ceftaroline|DRUG: Cefazolin / Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Linagliptin Response to OGTT in Prediabetes and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: PreDiabetes|Type 2 Diabetes
Interventions: DRUG: Dipeptidyl-Peptidase IV Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-effectiveness of Modified Pilates Method Versus Aerobic Exercise in Patients With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: OTHER: Pilates|OTHER: Aerobic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) on Cardiac Function in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease, COPD
Interventions: DRUG: QVA149|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Videolaryngoscopes In Double Lumen Tube
Status: UNKNOWN
Conditions: Videolaryngoscopy|Double Lumen Tube|One-lung Ventilation
Interventions: DEVICE: C-MAC Videolaryngoscope D blade|DEVICE: McGrath MAC Videolaryngoscope X3 blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Granulocyte Macrophage-Colony Stimulating Factor and Ipilimumab as Therapy in Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma, Metastatic
Interventions: BIOLOGICAL: Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Suvorexant in Patients With Chronic Obstructive Pulmonary Disease (MK-4305-032)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Empagliflozin on Body Composition and Ketones
Status: RECRUITING
Conditions: Diabetes Mellitus|Fat; Intolerance, Pancreas
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Hypoglycemics Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ROSA® Hip System THA PMCF
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Avascular Necrosis of Hip
Interventions: DEVICE: One of the following hip implants may be used within this arm of the study: G7 Acetabular System, Taperloc Complete System, Avenir and Avenir Complete Systems, and Echo Bi-Metric System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Tracheal Intubation Using the Totaltrack vs the Airtraq Laryngoscope in Difficult Airway Management
Status: UNKNOWN
Conditions: Endotracheal Intubation
Interventions: DEVICE: Orotracheal intubation with Totaltrack|DEVICE: Orotracheal intubation with Airtraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder
Status: RECRUITING
Conditions: Transcranial Alternating Current Stimulation|Depressive Disorder
Interventions: DEVICE: High definition transcranial alternating current stimulation|DEVICE: sham high definition transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil, Carnitine and PDE5 Inhibitor, Three Potential Treatments for Resistant Proteinuria Slowing Diabetic Nephropathy Deterioration
Status: UNKNOWN
Conditions: Diabetic Nephropathy|Chronic Kidney Disease
Interventions: DRUG: Mycophenolate Mofetil (MMF) ,phosphodiesterase 5 inhibitors , CARNITINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANGIOTENSIN AGENTS AND REDUCTION OF THE PRESCRIPTION OF ANTIDEPRESSANT DRUGS: A RETROSPECTIVE COHORT STUDY USING REAL-WORLD DATA
Status: UNKNOWN
Conditions: ACE Inhibitors|ARB|Hypertension|Depression
Interventions: DRUG: With an Antidepressant Drug|DRUG: Without an Antidepressant Drug
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Obtain Blood and Voided Urine Samples to Improve the Diagnosis of Melioidosis
Status: COMPLETED
Conditions: Melioidosis|Systemic Inflammatory Response Syndrome|Suspected or Confirmed Bloodstream Infections
Interventions: OTHER: Venous blood sampling (2 timepoints) (Phase A and B)|OTHER: Venous blood sampling (1 timepoint) (Phase A and B)|OTHER: Voided urine sampling (first sample) (Phase A)|OTHER: Voided urine sampling (second sample) (Phase A)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fish Oil (Omega 3 ) in Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjogren's Syndrome
Interventions: DRUG: Omega 3 fatty acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantation
Status: TERMINATED
Conditions: Graft Vs Host Disease
Interventions: DRUG: PRO 140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults
Status: COMPLETED
Conditions: Vitamin d Deficiency|Vitamin B 12 Deficiency|Protein Deficiency
Interventions: DIETARY_SUPPLEMENT: Use of food supplement|DIETARY_SUPPLEMENT: Use of placebo food supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Status: RECRUITING
Conditions: Anemia, Sickle Cell|Healthy Volunteers
Interventions: DRUG: BMS-986470|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adults
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: Velcade|DRUG: Methotrexate|DRUG: Methotrexate / Hydrocortisone / Cytarabine|DRUG: Dexamethasone|DRUG: Mitoxantrone|DRUG: Vincristine|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diclofenac on Pain During Endometrial Sampling
Status: UNKNOWN
Conditions: Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
Interventions: DRUG: Diclofenac Potassium|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telepharmacy Robotic Medicine Delivery Unit "TRMDU" Assessment
Status: WITHDRAWN
Conditions: Traumatic Brain Injury|Posttraumatic Stress Disorders|Trauma|Combat Disorders|Pain
Interventions: DEVICE: TMRDU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype
Status: COMPLETED
Conditions: Immunomodulatory Drugs|Killer-cell Immunoglobulin-like Receptors (KIRs)|KIR Alleles (KIR AA)
Interventions: DIAGNOSTIC_TEST: Killer-cell immunoglobulin-like receptors (KIRs) testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Transversus Abdominus Plain Block, Local Subcutaneous Injection and IV Nalbuphine
Status: COMPLETED
Conditions: Post Operative Pain|Cesarean Section Pain
Interventions: DRUG: NSAID , NALUFIN , local anesthetic andTAP Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Duloxetine, Placebo and Pelvic Floor Muscle Training in Subjects With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: DRUG: Duloxetine|PROCEDURE: Pelvic Floor Muscle Training (PFMT)|PROCEDURE: Imitation PFMT|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Patients With Unstable Angina Not Responding to Standard Medical Therapy Who Are Eligible for Coronary Angioplasty
Status: COMPLETED
Conditions: Angina, Unstable|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Abciximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotics and Hydroxychloroquine in Crohn's
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Ciprofloxacin|DRUG: Doxycycline|DRUG: Hydroxychloroquine|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Clinical Outcomes of Municipal Acute Wards Versus a General Hospital
Status: COMPLETED
Conditions: Quality of Life|Medical Emergencies|Mortality|Morbidity|Costs|Co-morbidity|Patient Experience
Interventions: OTHER: Level of healthcare services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MEDical CANnabis for Improving Symptoms During Severe DEMentia Disorders in Long-term Care Facility in Geneva
Status: RECRUITING
Conditions: Dementia With Behavioral Disturbance
Interventions: DRUG: Cannabis Sativa Oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor
Status: COMPLETED
Conditions: Kidney Transplantation Cytomegalovirus (CMV) Negative Recipients
Interventions: BIOLOGICAL: ASP0113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Effect of Eleclazine on QT, Safety, and Tolerability in Participants With Long QT2 Syndrome
Status: COMPLETED
Conditions: LQT2 Syndrome
Interventions: DRUG: Eleclazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: RADIATION: multiparametric MRI|PROCEDURE: kidney graft biopsy|BIOLOGICAL: blood samples|BIOLOGICAL: urine specimens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Relative Abuse Potential of Acurox Tablets in Non-Dependent Recreational Opioid Users
Status: COMPLETED
Conditions: Opioid Abuse
Interventions: DRUG: 40/0mg taken first|DRUG: 80/0mg taken first|DRUG: 40/240mg taken first|DRUG: 80/480mg taken first|DRUG: 0/0mg taken first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Gamma 3 Nail and ACE Trochanteric Nail
Status: COMPLETED
Conditions: Pertrochanteric and Subtrochanteric Femur Fractures
Interventions: DEVICE: Gamma 3 nail versus ACE trochanteric nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of pasireotideLAR and Topotecan in Relapsed or Refractory Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Topotecan and Pasireotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexmedetomidine for Emergence Delirium in Pediatric Patient
Status: RECRUITING
Conditions: Emergence Delirium|Dexmeditomidine
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of the Preservation of Muscle Mass and / or Its Recovery by a Protein-energy Chrononutrition Approach Dissociated From Meals
Status: TERMINATED
Conditions: Undernutrition
Interventions: DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Protein and Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Airway Clearance for Pediatric and Adult Cystic Fibrosis Patients Using a Portable Intra-Pulmonary Percussion Device
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Standard Airway Clearance device|DEVICE: Portable Internal Airway Percussion device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Pomegranate (Punica Granatum L.) Peel Compress Application on Pain and Physical Function Status
Status: ENROLLING_BY_INVITATION
Conditions: Pomegranate (P. Granatum) Peel Compress
Interventions: BEHAVIORAL: Pomegranate (Punica granatum) peel compress|BEHAVIORAL: Hot compress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With Toripalimab Sequential Chemotherapy as Neoadjuvant Treatment in Patients With HR-positive, HER2-low Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Disitamab Vedotin for Injection|DRUG: Toripalimab|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Docetaxel Plus Carboplatin in Patients With Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Daunorubicin Vs. Standard Dose Daunorubicin in Induction Treatment of AML
Status: COMPLETED
Conditions: ACUTE MYELOGENOUS LEUKEMIA
Interventions: DRUG: arm II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esketamine|DRUG: Ticlopidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cannabidiol in the Treatment of Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: Cannabidiol 200mg|DRUG: Epidiolex|DRUG: Cannabidiol 400mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal
Interventions: OTHER: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Immunogenicity and Safety of Zostavax® and Shingrix® in Rheumatoid Arthritis Patients Using Abatacept
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster|Inflammatory Disease|Rheumatoid Arthritis
Interventions: BIOLOGICAL: Varicella Zoster Vaccine|OTHER: Placebo Injection|BIOLOGICAL: Varicella Zoster Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neulasta® in Subjects With Advanced Non-Small-Cell Lung Cancer (NSCLC) During Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Neulasta® (pegfilgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Turner Syndrome Minipuberty Study
Status: RECRUITING
Conditions: Turner Syndrome|Infertility, Female|Premature Ovarian Failure|Gonadal Dysgenesis|Premature Menopause|Sex Chromosome Disorders|Ovarian Diseases
Interventions: OTHER: Venapunction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TAS-102 in Treating Advanced Biliary Tract Cancers
Status: COMPLETED
Conditions: Cholangiocarcinoma|Stage III Gallbladder Cancer AJCC v7|Stage IIIA Gallbladder Cancer AJCC v7|Stage IIIB Gallbladder Cancer AJCC v7|Stage IV Gallbladder Cancer AJCC v7|Stage IVA Gallbladder Cancer AJCC v7|Stage IVB Gallbladder Cancer AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Trifluridine/Tipiracil Hydrochloride Combination Agent TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Lymphocyte Therapy to Prevent Lymphoproliferative Disorders Caused by Epstein-Barr Virus in Patients Who Have Undergone Transplantation
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: allogeneic Epstein-Barr virus-specific cytotoxic T lymphocytes|BIOLOGICAL: autologous Epstein-Barr virus-specific cytotoxic T lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: LAYLA tablet|DRUG: CENATONE tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Esophageal Reinforcement With ACell MatriStem Surgical Matrix: A Degradable Biologic Scaffold Material
Status: COMPLETED
Conditions: Esophageal Adenocarcinoma
Interventions: DEVICE: MatriStem PSM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban for the Treatment of Venous Thromboembolism in Patients With Cancer
Status: UNKNOWN
Conditions: Venous Thromboembolism
Interventions: DRUG: Apixaban|DRUG: Dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part, Randomized Study of Dermacyte® Amniotic Wound Care Matrix
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Dermacyte Matrix|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Soft Tissue Contour Changes After Immediate Implant Placement With or Without Connective Tissue Graft
Status: RECRUITING
Conditions: Dental Implant Placement
Interventions: PROCEDURE: CTG and customized healing abutment|PROCEDURE: CTG and conventional healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.
Status: RECRUITING
Conditions: Ulcer, Gastric|Obesity, Morbid
Interventions: DRUG: Indocyanine green|DEVICE: Stryker 1688 AIM system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer
Status: UNKNOWN
Conditions: Oral Squamous Cell Carcinoma|Squamous Cell Carcinoma of Oropharynx|Squamous Cell Carcinoma of Hypopharynx|Oral Mucositis
Interventions: PROCEDURE: low level laser therapy|PROCEDURE: placebo (laser low level energy nonfunctional)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic Study of Aprepitant Injection in Humans
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Test (T) Aprepitant injection|DRUG: Reference (R) Aprepitant injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
Status: COMPLETED
Conditions: Metastatic Breast Cancer to the Brain
Interventions: DEVICE: 18F-FLT-PET Imaging|DEVICE: 18F-FLT-PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: COmpressioN Following Endovenous TreatmenT of Incompetent Varicose Veins
Status: COMPLETED
Conditions: Varicose Veins
Interventions: OTHER: Class 2 compression stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Pain Management at Triage on Opioid Consumption
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Paracetamol|DRUG: Tramadol/Paracetamol combination|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Innovative Functional Food Based on Apulian Lens Culinaris for Contrasting Sarcopenia in Dialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: NATURLENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Accuracy of Surgical Guide Designed From Digital Impression, Dental Model Scanning Using CBCT and Desktop Scanner in Computer Guided Implantology:
Status: UNKNOWN
Conditions: Computer Guided Implant
Interventions: DEVICE: Intra oral scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decreasing Nightmares in Adults With Narcolepsy
Status: NOT_YET_RECRUITING
Conditions: Narcolepsy|Narcolepsy Type 1|Narcolepsy With Cataplexy|Narcolepsy Without Cataplexy|Nightmare|Nightmare Disorder With Associated Other Sleep Disorder
Interventions: BEHAVIORAL: Imagery Rehearsal Therapy (IRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib Plus Sintilimab in the Treatment of Advanced Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Anlotinib + Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registration of the Study of Reyanning Mixture
Status: UNKNOWN
Conditions: Acute Tonsillitis
Interventions: DRUG: Reyanning mixture|DRUG: amoxil capsule|DRUG: Reyanning mixture simulator|DRUG: amoxil capsule simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-part Proof-of-Concept Study Assessing the Safety and Efficacy of LAT8881 in Lumbar Radicular Pain
Status: COMPLETED
Conditions: Radiculopathy Lumbar
Interventions: DRUG: LAT8881|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Myofunctional Therapy on Oral Dysphagia
Status: COMPLETED
Conditions: Dysphagia, Oral Phase|Temporomandibular Disorders
Interventions: PROCEDURE: Home Exercise|PROCEDURE: Manual Therapy Combined with Home Exercise|PROCEDURE: Orofacial Myofunctional Therapy combined with Manual Therapy and Home Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of BI 201335 in Patients With Mild to Severe Renal Impairment
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BI 201335|DRUG: BI 201335
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Triple Negative Breast Neoplasms|Triple-Negative Breast Neoplasm|Triple-Negative Breast Cancer|Triple Negative Breast Cancer|ER-Negative PR-Negative HER2-Negative Breast Neoplasms|ER-Negative PR-Negative HER2-Negative Breast Cancer
Interventions: BIOLOGICAL: Bavituximab|DRUG: Taxane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Immediate Release Formulations of ABBV-903 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: ABBV-903 Tablet Form 1|DRUG: ABBV-903 Tablet Form 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders
Status: RECRUITING
Conditions: Alcohol Use Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders|BEHAVIORAL: Take Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma
Status: RECRUITING
Conditions: Primary Glioblastoma
Interventions: COMBINATION_PRODUCT: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 200 J/cm^2|COMBINATION_PRODUCT: 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 400 J/cm^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Placebo|OTHER: L-methylfolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety and Local Tolerability Study of Chloroprocaine 3% Gel Eye Drops in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Ocular gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteral High-dose DHA Supplementation on Bronchopulmonary Dysplasia in Very Preterm Infants: a Collaborative Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchopulmonary Dysplasia|Child Development|Neonatal and Perinatal Conditions
Interventions: DIETARY_SUPPLEMENT: High-dose DHA|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Transcranial direct current stimulation (high- definition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury
Status: RECRUITING
Conditions: Neurological Diseases|Ischemic Stroke|Hemorrhagic Stroke|Cerebral Palsy|Atypical Parkinson Disease
Interventions: DRUG: Combination injection of EPO and G-CSF|DRUG: Injection of normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors
Status: RECRUITING
Conditions: Neuroblastoma|Solid Tumor
Interventions: DRUG: APG-115|DRUG: APG-2575
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment
Status: TERMINATED
Conditions: Sleep-Disordered Breathing|Pulmonary Arterial Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Different Doses of Ozone Therapy on Pain and Function of Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: Intra-articular injection of ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Status: COMPLETED
Conditions: Hearing Loss|Depression
Interventions: DEVICE: Phonak Audeo B-R 90 hearing aid device (Active)|DRUG: Duloxetine or escitalopram|DEVICE: Audeo B-R 90 hearing aid device (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fractional CO2 Laser in the Treatment for Cesarian Scar
Status: TERMINATED
Conditions: Cesarian Scar
Interventions: DEVICE: Fractional CO2 laser and pulsed dye laser|DEVICE: Pulsed dye laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure of Salvaged Blood to Inflammation and Oxidative Stress: the Effect of Different Anticoagulant Regimes (HECICS)
Status: COMPLETED
Conditions: Intra Operative Bleeding, Blood Salvage
Interventions: DRUG: ACD-A|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Respiratory Syncytial Virus (RSV) Investigational Vaccine in Infants Aged 6 and 7 Months Likely to be Unexposed to RSV
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV (GSK3389245A) lower dose formulation vaccine|BIOLOGICAL: RSV (GSK3389245A) higher dose formulation vaccine|BIOLOGICAL: GSK's multicomponent meningococcal B vaccine|BIOLOGICAL: Pfizer's meningococcal group A, C, W-135 and Y conjugate vaccine|BIOLOGICAL: GSK's pneumococcal polysaccharide conjugate vaccine|BIOLOGICAL: GSK's meningococcal group A, C, W-135 and Y conjugate vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Perfetti's Method on Cognition, Dexterity and Sensory Motor Function of the Upper Extremity in Stroke Patients
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: OTHER: routine physical therapy|OTHER: Perfetti's method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Status: COMPLETED
Conditions: Gingivitis; Chronic|Oxidative Stress|Inflammation
Interventions: OTHER: GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse)|OTHER: CHX-MW group (0.12% CHX, as a positive control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Investigational Regimen Combining FDA Approved HIV Drugs In HIV Subjects Experiencing Early Virologic Failure
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: abacavir/lamivudine/zidovudine|DRUG: tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Velcade Combined With High-Dose Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Cardiovascular Health in Adolescence
Status: COMPLETED
Conditions: Insomnia Type; Sleep Disorder
Interventions: OTHER: No pre-sleep arousal manipulation|OTHER: pre-sleep arousal down-regulation|OTHER: pre-sleep arousal up-regulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glycerin Suppositories Used Prophylactically in Premature Infants (SUPP): a Pilot Randomized Placebo-controlled Trial
Status: UNKNOWN
Conditions: Feeding Intolerance in Premature Infants
Interventions: DRUG: Glycerin Suppository|OTHER: Sham Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian Amazon
Status: COMPLETED
Conditions: Malaria, Vivax|Malaria, Falciparum
Interventions: DRUG: Pyrimethamine/sulfdoxine (Fansidar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loves Company: Combatting Emotional Disturbance in the Digital Age
Status: COMPLETED
Conditions: Adolescent - Emotional Problem
Interventions: OTHER: anonymous social support|OTHER: psychoeducation|OTHER: online resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Granisetron Versus Ondansetron for Nausea and Vomiting in Pediatric Age Group
Status: COMPLETED
Conditions: Nausea and Vomiting in Pediatric Age Group
Interventions: DRUG: Ondansetron Oral Film|DRUG: Granisetron Oral Liquid Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT