pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparative Study Between Open and Robotic Partial Nephrectomy in Treatment of High Complex Renal Tumors.
Status: UNKNOWN
Conditions: Renal Tumor
Interventions: PROCEDURE: partial nephrectomy for complex renal tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Distal Peripheral Neuropathy in Type 2 Diabetes
Status: COMPLETED
Conditions: Peripheral Neuropathy|Pain, Neuropathic|Diabetes
Interventions: OTHER: Moxibustion - Traditional (Active)|OTHER: Moxibustion - Smokeless - (Active)|OTHER: Placebo Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain
Status: UNKNOWN
Conditions: Pain, Intractable
Interventions: DRUG: oral methadone|DRUG: oral morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
Status: RECRUITING
Conditions: Stage IV Non-small Cell Lung Cancer|Stage IV Malignant Melanoma|Stage IV Small Cell Lung Cancer|Stage III Malignant Melanoma
Interventions: OTHER: Plasma sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimization of Osteoporosis Management Among Patients Older Than 45 Years Old With Low Energy Fracture.
Status: COMPLETED
Conditions: Osteoporosis, Management Care, Fracture
Interventions: BEHAVIORAL: Coordinator-based post fracture program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Range of Motion of Standard and High-Flexion Posterior Cruciate Retaining Total Knee Prostheses
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Total knee replacement with NexGen CR knee prosthesis|DEVICE: Total knee replacement(TKR) with Nexgen CR-flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additional GLP-1 Analogue on CSII Treatment for Poorly Controlled Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
Status: COMPLETED
Conditions: Surgical Incisions
Interventions: DEVICE: Suture|DEVICE: Dermabond Protape (Prineo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)
Status: TERMINATED
Conditions: Chronic Kidney Diseases|Alport Syndrome|Autosomal Dominant Polycystic Kidney
Interventions: DRUG: Bardoxolone methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secukinumab Therapy for the Treatment of Moderate to Severe Plaque Psoriasis With Response Monitoring Using Optical Coherence Tomography (OCT).
Status: UNKNOWN
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Japanese Men to Test How Well Different Doses of BI 1291583 Are Tolerated
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1291583|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Treatment|DRUG: Placebo|DRUG: Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caffeine for Preterm Infants With Apnea of Prematurity(AOP)
Status: UNKNOWN
Conditions: Caffeine|Apnea of Prematurity
Interventions: DRUG: 80mg/kg of caffeine|DRUG: 20mg/kg of caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Parecoxib IV/IM 40 Mg Vs Placebo Following Sub Muscular Breast Augmentation
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: PARECOXIB SODIUM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nitrazine in the Treatment of ALS
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Nitrofurazone Group 1|DRUG: Nitroketazine Group 2|DRUG: placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Drug Desensitization Protocol for Heart Transplant Candidates
Status: TERMINATED
Conditions: Heart Transplantation
Interventions: DRUG: Bortezomib, Thymoglobulin, Rituximab, Gamimune N, (IVIG), Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BFR Walking for Insulin and Aerobic Improvement in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: BFR Cuffs for Intervention Group|OTHER: Standard Walking Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot of Osanetant to Reduce Severity of Hot Flashes in Men With Adenocarcinoma of the Prostate
Status: WITHDRAWN
Conditions: Prostate Adenocarcinoma
Interventions: DRUG: Osanetant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0002012)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal and epidermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Type1 Diabetes Mellitus|Diabetes Mellitus, Type 1|Autoimmune Diabetes|Juvenile Diabetes|Diabetes Mellitus Complication|Diabetic Nephropathies|Metabolic Disease|Diabetic Kidney Disease
Interventions: DIAGNOSTIC_TEST: Blood draw|DIAGNOSTIC_TEST: Urine sample collection|DIAGNOSTIC_TEST: DXA scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Proof-of-Concept Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Hemophilic Arthropathy
Status: COMPLETED
Conditions: Hemophilic Arthropathy
Interventions: DRUG: Placebo|DRUG: AC-201CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients
Status: RECRUITING
Conditions: Pain Cancer
Interventions: DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Pain Experience Between Patients Who Have and Who Have Not Undergone Dermatologic Procedures
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Thermage|OTHER: Needle Application|DEVICE: VBeam Laser|DEVICE: Ulthera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of HVA Regimens as Salvage Treatment in rrAML
Status: COMPLETED
Conditions: Refractory Acute Myeloid Leukemia|Relapsed Acute Erythroid Leukemia|Salvage Treatment|HVA Regimen
Interventions: COMBINATION_PRODUCT: HVA Regimens as Salvage Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes|Vitamin B12 Deficiency|Neuropathy|Anemia
Interventions: BEHAVIORAL: Office visit intervention|BEHAVIORAL: Electronic Message Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Transvaginal Mesh vs. Laparoscopic Colposacropexy- Study
Status: RECRUITING
Conditions: Prolapse, Vaginal Vault
Interventions: PROCEDURE: TVM|PROCEDURE: Colposacropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methoxsalen and Extracorporeal Photopheresis (ECP) for the Treatment of Pediatric Participants With Steroid Refractory Acute Graft Versus Host Disease
Status: TERMINATED
Conditions: Steroid Refractory Acute Graft Versus Host Disease
Interventions: DRUG: Methoxsalen|PROCEDURE: Extracorporeal Photopheresis (ECP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of McGrath Videolaryngoscope to Assist Transesophageal Echocardiography Probe Insertion in Intubated Patients
Status: COMPLETED
Conditions: Other Complications of Surgical and Medical Procedures
Interventions: DEVICE: conventional technique|DEVICE: videolaryngoscope technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Open Label Multi-Dose Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing
Status: TERMINATED
Conditions: Anal Fissure
Interventions: DRUG: Nifedipine 12 mg coated suppositories
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography
Status: COMPLETED
Conditions: Obstructing Colorectal Cancer
Interventions: PROCEDURE: MR colonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Bioequivalence Study of 21 Milligram (mg) Nicotine Transdermal Patches (NicoDerm CQ, GlaxoSmithKline [GSK] Dungarvan) Compared to the Current Marketed 21 mg Nicotine Transdermal Patches (NicoDerm CQ, Alza) in Healthy Adult Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: NicoDerm CQ patch (GSK Dungarvan)|DRUG: NicoDerm CQ (Alza)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Health Education and Relationships Through Theater: An RCT of Promoting Awareness Through Live Movement and Sound for Youth With Autism Spectrum Disorder (PALMS-ASD)
Status: TERMINATED
Conditions: Sexual Health|Education, Health
Interventions: BEHAVIORAL: Promoting Awareness through Live Movement and Sound for youth with Autism Spectrum Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer
Status: COMPLETED
Conditions: Breastcancer|Breast Neoplasm
Interventions: BIOLOGICAL: SV-BR-1-GM|DRUG: Cyclophosphamide|BIOLOGICAL: Interferon-alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon Alfa and Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
Status: UNKNOWN
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: High Dose of Quetiapine in Treating Subjects With Treatment Refractory Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: quetiapine|DRUG: quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
Status: COMPLETED
Conditions: Coronavirus|Covid19|SARS-CoV-2|Severe Acute Respiratory Syndrome
Interventions: BIOLOGICAL: CVnCoV 6 μg|BIOLOGICAL: CVnCoV 12 μg|BIOLOGICAL: Hepatitis A vaccine|BIOLOGICAL: Pneumococcal vaccine|BIOLOGICAL: CVnCoV 12μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training After an Acute Blood Clot
Status: COMPLETED
Conditions: VTE
Interventions: BEHAVIORAL: VTE REHABILITATION: High-Caloric Expenditure Exercise Training (HCE) and The Dietary Behavioral Weight Loss Intervention (BWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technology-Enhanced Helping the Noncompliant Child
Status: COMPLETED
Conditions: Child Externalizing Behavior
Interventions: BEHAVIORAL: Helping the Noncompliant Child (HNC)|BEHAVIORAL: Technology-Enhanced Helping the Noncompliant Child (TE-HNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Center Comparison of 4 FDA Approved, Commercially Available Bowel Purgatives for Colonoscopy
Status: WITHDRAWN
Conditions: Patients Undergoing Screening or Surveillance Colonoscopy
Interventions: DRUG: PEG+E|DRUG: PEG+Asc|DRUG: P+MC|DRUG: sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Effect of Thymoglobulin and Reduced Doses of Steroids to Prevent Renal Transplant Rejection
Status: COMPLETED
Conditions: Renal Transplantation|Graft Rejection
Interventions: DRUG: Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin
Status: COMPLETED
Conditions: Gastric Ulcers|Duodenal Ulcers
Interventions: DRUG: TAK-438|DRUG: Placebo|DRUG: TAK-438|DRUG: Placebo|DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of Two Positive Body Image Micro-interventions for Children Aged 4-6 Years
Status: RECRUITING
Conditions: Body Image|Anti Fat Bias
Interventions: BEHAVIORAL: Positive body image TV show|BEHAVIORAL: Positive body image music video|BEHAVIORAL: Active control TV show about a visit to the dentist|BEHAVIORAL: Active control music video about brushing teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-axis Assessment of Injured Workers
Status: RECRUITING
Conditions: Musculoskeletal Injury|Musculoskeletal Strain|Low Back Pain|Neck Pain|Upper Extremity Injury|Lower Extremity Problem|Work-related Injury
Interventions: OTHER: Musculoskeletal-specific WSIB programs of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Abdominoplasty Under Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia Suitability for Abdominoplasty
Interventions: DRUG: Propofol 10 Mg/mL Intravenous Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients Receiving a Treatment Planning Study of 3 Dimensional Conformal Radiation Therapy Guided by Breath Held CT and PET Imaging for Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: PROCEDURE: Positron Emission Tomography (PET) scan Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brief Admission Skane: Replacing General Admission for Individuals With Self-harm and Acute Risk of Suicide
Status: COMPLETED
Conditions: Self-Injurious Behavior|Suicidal Ideation|Suicide, Attempted|Borderline Personality Disorder|Emergency Services, Psychiatric
Interventions: OTHER: Brief Admission
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck (SCCHN)|Recurrent Squamous Cell Carcinoma of the Head and Neck|Metastatic Head and Neck Cancer|Advanced Head and Neck Cancer|Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Duvelisib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacral Transcutaneous Electrical Stimulation Efficacy in Chronic Pelvic Pain: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DEVICE: Sham TENS Stimulation|DEVICE: Sacral TENS Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Venetoclax, a BCL2 Antagonist, for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
Status: UNKNOWN
Conditions: Post-concussion Syndrome|Post-concussive Symptoms|Traumatic Brain Injury|Concussion|Children
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Setting Benchmarks for Microsurgical Clipping of Unruptured Intracranial Aneurysms
Status: UNKNOWN
Conditions: Aneurysm|Aneurysm, Brain|Aneurysm Cerebral|Aneurysm of Cerebral Artery|Aneurysm, Intracranial
Interventions: PROCEDURE: Microsurgical Clipping of Unruptured Intracranial Aneurysm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: LSD (150 µg) + ketanserin (40 mg)|DRUG: LSD (150 µg) + olanzapine (10 mg)|DRUG: LSD (150 µg) + lorazepam (2 mg)|DRUG: LSD (150 µg) + placebo|DRUG: Placebo + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: fluticasone 100mcg/ salmeterol 50mcg|DRUG: fluticasone 250/salmeterol 50|DRUG: salmeterol|DRUG: Salmeterol|DRUG: salmeterol and fluticasone propionate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Primary Care Clinicians' Responses to a Hypoglycemia Risk Calculator for Diabetes Mellitus in Ambulatory Care
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus
Interventions: OTHER: Clinical decision support via alert tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis
Status: UNKNOWN
Conditions: Acute Cholecystitis|Empyema
Interventions: PROCEDURE: Surgical drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Postoperative Antibiotics in Orthognathic Surgery
Status: UNKNOWN
Conditions: Asymptomatic Diseases
Interventions: DRUG: Amoxicillin Clavulanate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Profile of Neupro Patch Administrated at 2 mg, 4 mg, 6 mg and 8 mg/Day Weekly in Patients With Early-stage Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: ROTIGOTINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Color Priming and Patient Decision-Making in the Emergency Department: Priming "Threat" in Patients With Low-Risk Chest Pain
Status: COMPLETED
Conditions: Chest Pain|Cardiac Event
Interventions: OTHER: Black and White Printed Survey|OTHER: Red Printed Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Clinical and Radiographic Outcomes of a 3D-printed Patient-specific Biomimetic Bone Substitute in Maxillofacial Indications: an Interventional, Multi-centred, Open-label, Post-market Clinical Investigation.
Status: UNKNOWN
Conditions: Bone Regeneration
Interventions: PROCEDURE: Surgical reconstruction of maxillofacial osseous defect with MimetikOss 3D.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis
Status: TERMINATED
Conditions: Primary Sclerosing Cholangitis|Compensated Cirrhosis
Interventions: DRUG: Cilofexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Surgical and Economical Parameters of Total Knee Replacement.
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Total Knee Arthroplasty
Interventions: DEVICE: MyKnee with single use Efficiency Instrument|DEVICE: Stryker Navigational with conventional metal instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative EEG (QEEG) as a Predictor of Treatment Outcome in Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Selective serotonin reuptake inhibitors (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events (AEs) When Oral Atogepant Tablet is Given to Adult Chinese Participants Who Completed Study 3101-303-002 to Prevent Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine
Interventions: DRUG: Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects Of DP-b99 On Neurological Function In Subjects With Acute Ischemic Hemispheric Stroke
Status: COMPLETED
Conditions: Brain Ischemia|Stroke|Cerebrovascular Disorders
Interventions: DRUG: DP-b99
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-5013 plus dexamethasone|DRUG: Dexamethasone plus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy of Simulator Training for Fiberbronchoscopy in Intensivists
Status: UNKNOWN
Conditions: Simulator Training
Interventions: DEVICE: Bronchoscopy training simulator LM-092 (Koken Co., Ltd, Tokyo, Japan)|DEVICE: The BRONCH Mentor (Simbionix, GI-Bronch Mentor, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Lower Limb and Groin Injuries: the Sport Without Injury ProgrammE (SWIPE) Football Trial
Status: COMPLETED
Conditions: Athletic Injuries
Interventions: OTHER: Knee Control+ program|OTHER: Adductor strengthening program|OTHER: Knee Control program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Local Anaesthetic Infusion For Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Levobupivicaine|DRUG: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Clinical Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in Canada
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Tranexamic Acid in Upper Gastrointestinal Bleeding
Status: WITHDRAWN
Conditions: Gastrointestinal Hemorrhage
Interventions: DRUG: tranexamic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Infliximab, methylprednisolone, methotrexate|DRUG: Methotrexate|DRUG: Methotrexate + Methylprednisolone|DRUG: Methotrexate + Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids as a Treatment for Insomnia in Major Depression
Status: RECRUITING
Conditions: Insomnia|Depressive Disorder, Major|Sleep Disorder|Depression|Insomnia Chronic
Interventions: DRUG: 25:1 CBD/THC|DRUG: 5:1 CBD/THC|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fourth Generation CART-cell Therapy for Refractory-Relapsed Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: anti- MESO CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonpharmacological Approaches and Parental Education in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Nursing Caries
Interventions: OTHER: nonpharmacological approaches to parents of children with sickle cell disease training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cyclophosphamide and Rituximab Followed By Vaccine Therapy in Treating Patients With Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Leukemia
Interventions: BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: rituximab|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Placebo Effect May Involve Modulating Drug Bioavailability
Status: COMPLETED
Conditions: Placebo Effect|Drug Half Life|Pharmacokinetics
Interventions: DRUG: Caffeine, paracetamol, cephalexin, or ibuprofen|DRUG: Placebo (caffeine, paracetamol, cephalexin, or ibuprofen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer Bleeding
Status: TERMINATED
Conditions: Gastric Cancer|Bleeding
Interventions: DRUG: Proton pump inhibitor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of HGP1207 in Patients With Pulmonary Hypertension
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Systolic Dysfunction
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Shivering Treatment After Cesarean Delivery: Meperidine vs. Dexmedetomidine
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Dexmedetomidine Injection|DRUG: Meperidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease (0653-023)(COMPLETED)
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DRUG: MK0653, ezetimibe / Duration of Treatment: 27 Weeks|DRUG: MK0733, simvastatin / Duration of Treatment: 27 Weeks|DRUG: Comparator: simvastatin / Duration of Treatment: 27 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Racotumomab Versus Support Treatment in Advanced Non-small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: racotumomab|OTHER: Best support treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mometasone Furoate Aqueous (MK-0887/SCH 032088) Nasal Spray vs Placebo and FLONASE® in Seasonal Allergic Rhinitis Patients (I94-001)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: Mometasone furoate|DRUG: Fluticasone propionate|DRUG: Mometasone furoate placebo|DRUG: Fluticasone propionate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Linagliptin in Combination With Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects and Consequences for Mother and Child From Treatment for Depression
Status: TERMINATED
Conditions: Pregnancy|Moderate Depression
Interventions: DRUG: Zoloft|BEHAVIORAL: ICBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abatacept for the Treatment of Giant Cell Arteritis
Status: RECRUITING
Conditions: Giant Cell Arteritis
Interventions: DRUG: Abatacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Play as a Method to Reduce Overweight and Obesity in Children.
Status: COMPLETED
Conditions: Childhood Obesity|Sleep Apnea in Obese Children|Studying Maternal and Family Factors That Cause Obesity in Children
Interventions: BEHAVIORAL: The intervention consisted of physical activity based on play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fenofibrate on Kidney Function: a Six-week Randomized Cross-over Trial in Healthy People
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Fenofibrate 160 mg tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Multicenter Study of the Safety and Anti Viral Activity of Brincidofovir (BCV, CMX001) for Ebola Virus Disease
Status: WITHDRAWN
Conditions: Ebola Virus
Interventions: DRUG: CMX001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Magnesium for Same-day-surgery
Status: TERMINATED
Conditions: Transient Neurologic Syndrome
Interventions: DRUG: Magnesium sulfate|DRUG: Fentanyl|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Mulligan Squeeze Technique on Meniscal Derangement in Knee Osteoarthritis Patients
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Knee Injuries|Meniscus; Derangement|Meniscus Tear|Meniscus Lesion
Interventions: OTHER: Mulligan's Squeeze Technique - manual therapy|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dornase Alfa Therapy for Ventilator Associated Lung Infections in the Neonatal Intensive Care Unit (NICU)
Status: COMPLETED
Conditions: Pulmonary Infections
Interventions: DRUG: Dornase alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Anlotinib Therapy for Initially Unresectable Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sintilimab|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children
Status: RECRUITING
Conditions: Insufficient Sleep|Obesity
Interventions: BEHAVIORAL: Fixed sleep goal|BEHAVIORAL: Personalized sleep goal|BEHAVIORAL: Digital sleep health messaging without virtual study visit|BEHAVIORAL: Digital sleep health messaging with virtual study visit|BEHAVIORAL: Inactive Parent-Directed Loss-Framed Incentive|BEHAVIORAL: Active Parent-Directed Loss-Framed Incentive|BEHAVIORAL: Inactive Supportive Feedback|BEHAVIORAL: Active Supportive Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Identification of Drug-drug Interaction Between Tacrolimus and Mycophenolate Mofetil in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Tacrolimus|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From Jail
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: Extended-Release Naltrexone|BEHAVIORAL: Motivational Enhancement Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Open Label Trial of Brentuximab Vedotin (SGN-35) for Systemic Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Anaplastic|Lymphoma, Non-Hodgkin
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4delta30) in Healthy Adults
Status: COMPLETED
Conditions: West Nile Fever
Interventions: BIOLOGICAL: WN/DEN4delta30 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Neoplasms|Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Alisertib in Adults With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Function
Status: COMPLETED
Conditions: Advanced Solid Tumors|Relapsed/Refractory Lymphoma
Interventions: DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RSV-HMPV Bivalent Vaccine VXB-241 in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: VXB-241 60 mcg (Low Dose)|BIOLOGICAL: VXB-241 120 mcg (Medium Dose)|BIOLOGICAL: VXB-241 240 mcg (Medium-high Dose)|BIOLOGICAL: VXB-241 480 mcg (High Dose)|BIOLOGICAL: VXB-241|OTHER: Placebo|BIOLOGICAL: Arexvy 120 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Stenosis|Coronary Disease|Coronary Stenosis
Interventions: DEVICE: Percutaneous Coronary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HUMC 1612: Optune NovoTTF-200A System
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma|Ependymoma
Interventions: DEVICE: Optune NovoTTF-200A System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Biofeedback System Versus Conventional Rehabilitation After Rotator Cuff Repair
Status: TERMINATED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: Digital kinematic biofeedback device|OTHER: Conventional rehabilitation|OTHER: Additional face-to-face rehabilitation sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Blood Biomarkers of Mitochondrial and Peroxisomal Metabolism to Differentiate Idiopathic Parkinson's Disease From Related Conditions
Status: UNKNOWN
Conditions: Idiopathic Parkinson Disease|Parkinsonian Syndrome
Interventions: BIOLOGICAL: blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polypropylene vs Polyglactin in Suturing of the Lung
Status: NOT_YET_RECRUITING
Conditions: Lung Injury|Bleb Lung|Lung Cancer
Interventions: PROCEDURE: lung suturing with polyglactin|PROCEDURE: ung suturing with polypropylene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectivity of Motor Imagery and MirrorTherapy in Amputees
Status: COMPLETED
Conditions: Amputees
Interventions: OTHER: Treatment Traditional and Imaginary Motor Program|OTHER: Treatment Traditional and Mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant in Preventing Nausea and Vomiting in Patients Who Are Undergoing a Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: aprepitant|DRUG: dexamethasone|DRUG: ondansetron|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Can Transcutaneous Electrical Acupoint Stimulation Improve the Quality of Recovery After Thyroidectomy?
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DEVICE: the Hans electronic acupuncture apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones
Status: TERMINATED
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: OTHER: Questionnaire Administration|RADIATION: Tin Sn 117m Pentetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Quitting Versus Using Aspirin Therapy In Patients Treated With Oral Anticoagulation for Atrial Fibrillation or Other Indication With Stabilized Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: OAC + Aspirin 100mg od|DRUG: OAC + placebo of Aspirin 100mg od
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perception of Efficacy, Safety and Tolerability of Three Non-hormonal Intravaginal Gels and Hormone Cream
Status: UNKNOWN
Conditions: Vaginal Dryness
Interventions: OTHER: Hidrafemme|OTHER: Vagidrat|OTHER: Lubrinat|OTHER: Antrofi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Calcium Citrate Versus Calcium Carbonate for the Management of Chronic Hypoparathyroidism
Status: COMPLETED
Conditions: Chronic Hypoparathyroidism
Interventions: DRUG: Calcium Carbonate|DRUG: Calcium Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer
Status: COMPLETED
Conditions: Hereditary Breast and Ovarian Cancer
Interventions: OTHER: Breast Cancer Genetics Referral Screening Tool 3.0|OTHER: Standard Handout|OTHER: Physician Notification|OTHER: Automatic Follow-Up by Genetic Counseling Staff
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Nicotine Patch|DRUG: SPECTRUM Nicotine Research Cigarettes (.03 mg)|BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Supportive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE