pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Target Occupancy Study With Ritlecitinib.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ritlecitinib 50 mg|DRUG: Ritlecitinib 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Efficacy of Troxerutin in Preventing Thrombotic Events in COVID-19 Patients
Status: RECRUITING
Conditions: COVID 19 Associated Coagulopathy
Interventions: DRUG: Troxerutin|DRUG: Placebo|DRUG: placebo + low molecular weight heparin|DRUG: troxerutin + low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma
Status: RECRUITING
Conditions: Cryopreservation|Ovary Injury|Infertility, Female|Menopause Ovarian Failure
Interventions: PROCEDURE: Cryopreserved Ovarian Tissue Reimplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boosting REcanalization of Thrombectomy for Ischemic Stroke by Intra-arterial TNK (BRETIS-TNK)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: intra-arterial tenecteplase administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study to Compare the Pharmacodynamics of Torasemide-PR 10 mg,Torasemide-IR 10 mg and Furosemide-IR 40 mg in Patients With Compensated Heart Failure
Status: TERMINATED
Conditions: Compensated Heart Failure
Interventions: DRUG: torasemide-PR|DRUG: Furosemide-IR|DRUG: torasemide-IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Ridge Splitting Technique Using Autogenous Bone Blocks (MRS)
Status: UNKNOWN
Conditions: Alveolar Bone Resorption|Alveolar Ridge Enlargement
Interventions: PROCEDURE: Alveolar ridge splitting|DEVICE: Creating osteotomies with piezoelectric device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Diabetic Macular Edema With 0.5mg Intraocular Ranibizumab (Lucentis)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Lucentis (Ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Platelet-rich Plasma Use as Prophylactic of Low Back Pain Post-spinal Following Gynecological Surgery
Status: UNKNOWN
Conditions: Platelet-rich Plasma in Low Back Pain
Interventions: OTHER: Platelet-rich Plasma|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma
Interventions: DRUG: Carboplatin|RADIATION: 3 Dimensional Conformal Radiation Therapy|DRUG: Propranolol|RADIATION: Intensity Modulated Radiation Therapy|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management
Status: UNKNOWN
Conditions: Cervical Cancer|Endometrial Cancer
Interventions: PROCEDURE: Superior Hypogastric Plexus Block|PROCEDURE: Ganglion Impar Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Study of 250-mg ZD1839 Monotherapy in Recurrent or Metastatic or Both Recurrent and Metastatic Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: ZD1839 (IRESSA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|HER2-positive Breast Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: Omission of sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Arterial Measurement of the Blood Flow Volume After Iloprost Stimulation
Status: UNKNOWN
Conditions: Diabetes|Arteriosclerosis|Peripheral Arterial Occlusive Disease|Neuropathy
Interventions: DRUG: Ilomedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Reality Navigation System (Endosight) for the Guidance of Bone Biopsy
Status: COMPLETED
Conditions: Bone Lesion|Bone Tumor|Bone Infection
Interventions: PROCEDURE: 8 Patients who were prescribed a CT-guided percutaneous bone biopsy, performed with the aid of endosight navigation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Monitoring Response After The First Chemotherapy Cycle After Neoadjuvant Breast Cancer Therapy
Status: UNKNOWN
Conditions: Invasive Ductal Carcinoma|Lobular Breast Carcinoma|Inflammatory Breast Carcinoma
Interventions: PROCEDURE: PET scan after course 1 and surgery after 8 courses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Tezampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: 0.5% timolol|DRUG: timolol-dorzolamide fixed combination|DRUG: Latanoprost|DRUG: Travoprost|DRUG: Bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inducing Remission in Type 1 Diabetes With Alefacept
Status: TERMINATED
Conditions: New-onset Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Alefacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobility Optimization Through Velocity Exercise
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Gait Training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Computer-adaptive Chronic Kidney Disease Education Program
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Hypertension
Interventions: BEHAVIORAL: Computerized CKD Education|BEHAVIORAL: Usual Hospital Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexmedetomidine Versus Fentanyl as Adjuvants to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Bupivacaine|DRUG: Dexmedetomidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids
Status: COMPLETED
Conditions: Internal Hemorrhoids
Interventions: DRUG: Anucort-HC, 25 Mg Rectal Suppository|DRUG: Placebo suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ulnar Nerve Block for Procedural Anesthesia - Wrist Versus Palm
Status: TERMINATED
Conditions: Hand Surgery
Interventions: PROCEDURE: Volar Wrist Block|PROCEDURE: Hypothenar Palm block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Comfort of AL-4943A Ophthalmic Solution
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine hydrochloride ophthalmic solution, 0.7%|DRUG: Olopatadine hydrochloride ophthalmic solution vehicle|DRUG: Ketotifen fumarate ophthalmic solution, 0.025%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: TMS in the Treatment of the Sequelae of Closed Brain Injury
Status: COMPLETED
Conditions: Depression|Closed Head Injury
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ibuprofen and Acetaminophen for Treatment of Acute Headache Post Concussion in Children
Status: COMPLETED
Conditions: Concussion|Headache
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Pembrolizumab in Patients With Metastatic Non-squamous Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non-Squamous Non-Small Cell Lung Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide (CTX)|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Dexamethasone|DRUG: Methotrexate (MTX)|DRUG: Cytarabine|DRUG: G-CSF|DRUG: Mesna|DRUG: Pegylated asparaginase|DRUG: Pegfilgrastim|DRUG: Solumedrol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sinetrol® Xpur in Fat Mass Reduction on Overweight and Obese Subjects
Status: COMPLETED
Conditions: Change in Total Body Fat Mass Percentage Loss Versus Body Weight
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Sinetrol® Xpur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: acupoint stimulation|OTHER: non-acupoint stimulation|OTHER: electrode attached|DEVICE: electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Adjunctive to Endovascular Treatment for Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phacotrabeculectomy Versus Phacogoniotomy (PVP) in Advanced Primary Angle-closure Glaucoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma, Angle-Closure
Interventions: PROCEDURE: phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy|PROCEDURE: phacoemulsification with intraocular lens implantation combined with trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenofibrate for Prevention of DR Worsening
Status: RECRUITING
Conditions: Diabetic Retinopathy
Interventions: DRUG: Fenofibrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Early Life Stress and Depression
Status: COMPLETED
Conditions: Major Depressive Disorder (MDD)|History of Childhood Sexual Abuse (CSA)
Interventions: DRUG: Amisulpride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interventional Practices and Their Effectiveness in Infants With İnfantyl Colic
Status: ACTIVE_NOT_RECRUITING
Conditions: Nurse's Role|Infantile Colic
Interventions: OTHER: Foot massage|OTHER: Mother heart sound|OTHER: Foot massage and maternal heart sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glivec in Prostate Cancer Patients With Rising PSA Following Radical Prostectomy
Status: COMPLETED
Conditions: Prostatic Neoplasm|Genital Neoplasms, Male|Neoplasms, Abdominal|Urogenital Neoplasms|Genital Diseases, Male|Prostatic Diseases|Antineoplastic Agents|Imatinib
Interventions: DRUG: STI571 (Glivec®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Etoposide, Cisplatin, and Radiotherapy Versus Paclitaxel, Carboplatin and Radiotherapy to Treat Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: Chemoradiotherapy Regimen between PC and PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Safety of High-frequency Radio Wave Electrotherapy With a Radio Frequency of 448 kHz in the Treatment of Patients With Organic Erectile Dysfunction.
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DEVICE: high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.|DEVICE: high-frequency radio wave electrotherapy with a frequency of 448 kHz on the penis structures.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Epigenomic and Machine Learning Models to Predict Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DIAGNOSTIC_TEST: Early diagnosis for Pancreatic Cancers in high-risk asymptomatic subject groups
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quetiapine Versus Trazadone in Women With Postpartum Depression
Status: NOT_YET_RECRUITING
Conditions: Postpartum Depression
Interventions: DRUG: Trazodone|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mesenchymal Stem Cell Secretome in Lupus Patients
Status: COMPLETED
Conditions: Lupus Erythematosus
Interventions: DRUG: Secretome|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology
Status: UNKNOWN
Conditions: Cancer|Solid Tumor|Hematologic Malignancy|Oral Drug Administration
Interventions: DEVICE: TreC-Onco|OTHER: Paper diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity|Lipodystrophy
Interventions: DRUG: Pravastatin sodium|DRUG: Simvastatin|DRUG: Atorvastatin calcium|DRUG: Nelfinavir mesylate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Chewing Gum and Use of Stress Balls on Perception of Labor Pain, Fear of Birth, and Duration of Delivery
Status: COMPLETED
Conditions: Labor Pain|Birth Satisfaction|Duration of Birth
Interventions: OTHER: stress ball|OTHER: chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT
Status: SUSPENDED
Conditions: Haematological Malignancies|CMV Infection
Interventions: GENETIC: CMV-TCR transduced donor-derived T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anal Dysplasia Study of Men Who Have Sex With Men Living With HIV
Status: WITHDRAWN
Conditions: Anal Dysplasia|Human Papilloma Virus|HIV
Interventions: DRUG: imiquimod|PROCEDURE: ablative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Morphine Sulfate|OTHER: Intravenous Placebo for NTM-001|OTHER: IV Placebo for Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vitamin D3 Substitution to Patients With Primary Immunodeficiency
Status: COMPLETED
Conditions: Primary Immune Deficiency Disorder
Interventions: DRUG: Vigantol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercise Timing on Energy Intake and Appetite in Adolescents With Obesity: the TIMEX 3 Study
Status: UNKNOWN
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: CON|BEHAVIORAL: EX-30|BEHAVIORAL: EX-90
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Versus Open Excision of Dorsal Wrist Ganglion
Status: NOT_YET_RECRUITING
Conditions: Hand Ganglion
Interventions: PROCEDURE: excision of dorsal wrist ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of QTc Interval by Continuous Holter ECG Recording in Antipsychotic Drug-treated Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective|Bipolar Disorder
Interventions: DEVICE: Holter Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Phase II Trial Comparing Therapy Based on Tumor Molecular Profiling Versus Conventional Therapy in Patients With Refractory Cancer
Status: UNKNOWN
Conditions: Reccurent/Metastatic Solid Tumor Disease
Interventions: DRUG: Targeted therapy based on molecular profiling : Imatinib|PROCEDURE: Tumor biopsy|DRUG: Standard Chemotherapy|DRUG: Targeted therapy based on molecular profiling : Everolimus|DRUG: Targeted therapy based on molecular profiling : Vemurafenib|DRUG: Targeted therapy based on molecular profiling : Sorafenib|DRUG: Targeted therapy based on molecular profiling : Erlotinib|DRUG: Targeted therapy based on molecular profiling : Lapatinib + Trastuzumab|DRUG: Targeted therapy based on molecular profiling : Dasatinib|DRUG: Targeted therapy based on molecular profiling : Tamoxifen (or letrozole if contra-indication)|DRUG: Targeted therapy based on molecular profiling : Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Short Breast MRI (SBMRI) for Screening Patients at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Short Breast MRI (SBMRI)|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Men's Club: Impact of Male Partner Involvement on Initiation and Sustainment of Exclusive Breastfeeding Among Postpartum Women
Status: UNKNOWN
Conditions: HIV Infections|Breastfeeding, Exclusive
Interventions: BEHAVIORAL: Men's Club
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inspiratory Muscle Training and Nasal High Flow in Difficult Weaning
Status: UNKNOWN
Conditions: High-risk for Reintubation Patients|Weaning Outcome
Interventions: OTHER: Inspiratory muscle Training and Nasal High Flow|DEVICE: Inspiratory muscle training and Venturi mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Niclosamide In Moderate COVID-19
Status: WITHDRAWN
Conditions: COVID
Interventions: DRUG: Niclosamide Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: RADIATION: indium In 111 monoclonal antibody MN-14|RADIATION: yttrium Y 90 monoclonal antibody MN-14
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerability, Safety, Pharmacokinetics of HEC89736 in Patients With Relapsed or Refractory B-cell Hematologic Malignancies
Status: UNKNOWN
Conditions: Relapsed or Refractory B-cell Hematologic Malignancies
Interventions: DRUG: HEC89736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Reduction: Mechanical vs Chemical
Status: COMPLETED
Conditions: Multiple Pregnancy
Interventions: DEVICE: Transvaginal ultrasound|PROCEDURE: Mechanical fetal reduction|PROCEDURE: Chemical fetal reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis
Status: COMPLETED
Conditions: Recurrent Tonsillitis in Children
Interventions: DRUG: DL - Lactic Acid|DIETARY_SUPPLEMENT: Raspberry flavored syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant FEC Versus EP in Breast Cancer (MIG5)
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy, Adjuvant
Interventions: DRUG: 5-fluorouracil|DRUG: epirubicin|DRUG: cyclophosphamide|DRUG: epirubicin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle-free Delivery of Intralesional Triamcinolone for Pediatric Alopecia Areata
Status: TERMINATED
Conditions: Alopecia Areata
Interventions: COMBINATION_PRODUCT: MedJet Device with intralesional triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 4DX for the Diagnosis of Constrictive Bronchiolitis
Status: COMPLETED
Conditions: Constrictive Bronchiolitis
Interventions: DIAGNOSTIC_TEST: X-ray velocimetry analyzed by 4Dx XV Ventilation Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Hemodynamic Effects of PEEP According to Alveolar Recruitment During the ARDS
Status: UNKNOWN
Conditions: ARDS, Human|Ventilation Therapy; Complications|Alveolar; Disorder
Interventions: DEVICE: Pulmonary artery catheter|DEVICE: Esophagal pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: DRUG: indocyanine green solution|OTHER: diffuse optical imaging|PROCEDURE: robot-assisted laparoscopic surgery|PROCEDURE: therapeutic lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EVITA: Evaluation of VIP Feature in Pacemaker Patients
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DEVICE: Device: St. Jude Medical Victory dual-chamber pacemaker|DEVICE: Ventricular Intrinsic Preference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of A Nutritional Supplements' Combination (FERTILIS) on Male Infertility
Status: UNKNOWN
Conditions: Infertility, Male|Subfertility, Male
Interventions: DIETARY_SUPPLEMENT: FERTILIS HOMME®|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Assessment of Cavernosal Nerve Stimulus Threshold
Status: COMPLETED
Conditions: Prostatectomy
Interventions: DEVICE: 10Hz + 100 micro-seconds|DEVICE: 10Hz + 200 micro-seconds|DEVICE: 7Hz + 100 micro-seconds|DEVICE: 7Hz + 200 micro-seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BGB-R046 as Monotherapy and in Combination With Tislelizumab in Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: BGB-R046|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With AML
Status: RECRUITING
Conditions: Acute Myelocytic Leukemia
Interventions: BIOLOGICAL: Unrelated umbilical cord blood|DRUG: Venetoclax|DRUG: Decetabine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Group Acceptance and Commitment Therapy in Treating Acute Stroke Patients With Depression
Status: COMPLETED
Conditions: Acute Stroke Patients With Depression
Interventions: BEHAVIORAL: Group-based Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib/Doxil in Adv Relapsed Plat Sensitive or Resistant Ovarian, Fallopian or Primary Peritoneal Adenocarcinoma
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Carcinoma
Interventions: DRUG: Pazopanib|DRUG: Doxil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gain More Information on How Safe and Effective Jivi Works in Patients With Severe Hemophilia A (Post-marketing Investigation)
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Damoctocog alfa pegol (Jivi, BAY94-9027)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Therapy in Metastatic Renal Cell Carinoma
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Avastin in combination with Roferon-A|DRUG: Afinitor|DRUG: TKI: Sutent, Nexavar or Votrient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: GTI-2040
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Pharmacokinetics, Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) Fixed Dose Combination (FDC) in Adolescents and Children With Chronic Hepatitis C Virus (HCV) Infection
Status: TERMINATED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL/VOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib as Second-line Treatment for Advanced/Metastatic Biliary Tract Adenocarcinoma
Status: UNKNOWN
Conditions: Biliary Tract Adenocarcinoma
Interventions: DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
Status: COMPLETED
Conditions: Labor Pain|Complications; Cesarean Section|Pregnancy
Interventions: DRUG: Epidural anesthesia|DRUG: Combined spinal and epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of TS-134 on Ketamine-induced BOLD Signals in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TS-134|DRUG: TS-134|DRUG: Placebo|OTHER: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endovascular Management of Pediatric Intracranial Arteriovenous Shunts
Status: COMPLETED
Conditions: Arteriovenous Malformations|Arteriovenous Fistula
Interventions: PROCEDURE: endovascular embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nolpitantium Besylate In Patients With Ulcerative Colitis a Double-Blind, Placebo Controlled Efficacy and Safety Study
Status: COMPLETED
Conditions: Ulcerative Colitis|Inflammatory Bowel Disease
Interventions: DRUG: Nolpitantium besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing DMSB01 and Rejuran® for Temporary Crow's Feet Lines Improvement
Status: NOT_YET_RECRUITING
Conditions: Crow's Feet Lines
Interventions: DEVICE: DMSB01|DEVICE: Rejuran®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and TRC105 in Hepatocellular Cancer
Status: COMPLETED
Conditions: Hepatoma|Liver Neoplasms|Adenoma, Liver Cell|Carcinoma, Hepatocellular|Liver Neoplasms, Experimental
Interventions: DRUG: TRC 105|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease-2
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: OTHER: 3T CMR|OTHER: SPECT|OTHER: CT calcium score|OTHER: CT coronary angiography|OTHER: X-Ray coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment
Status: COMPLETED
Conditions: Recurrent Childhood Medulloblastoma
Interventions: DRUG: vismodegib|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Equivalence of Ramipril 10 mg and Atorvastatin 40 mg Administered as a Cardiovascular (CV) Polypill Acetylsalicylic Acid-Atorvastatin-Ramipril (AAR) as Compared to Monotherapy
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Cardiovascular Fixed Dose Combination Pill AAR|DRUG: Atorvastatin 40 mg|DRUG: Ramipril 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Based Uveitis Screening for Children With Juvenile Idiopathic Arthritis
Status: NOT_YET_RECRUITING
Conditions: Uveitis, Anterior|Juvenile Idiopathic Arthritis
Interventions: DIAGNOSTIC_TEST: AS-OCT imaging|DIAGNOSTIC_TEST: Slit lamp examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Combination Chemotherapy and Thalidomide in Treating Patients With Stage I, Stage II, or Stage III Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: thalidomide|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial)
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Methotrexate|DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oocyte Retrieval and Virtual Reality (REVPO)
Status: RECRUITING
Conditions: Oocyte Retrieval|Pain|Fertilization in Vitro
Interventions: DEVICE: Hypnotic relaxation induced by virtual reality (device)|DRUG: local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The DIEP Flap as a Model of Ischemia-Reperfusion: an Intervention Study
Status: UNKNOWN
Conditions: Ischemia-Reperfusion
Interventions: DRUG: Antioxidant|OTHER: Placebo|DRUG: Anti-inflammatory drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04208)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Mometasone Furoate Nasal Spray|DRUG: fluticasone nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Carbohydrate High Fat Ketogenic vs. Non-ketogenic Diet
Status: COMPLETED
Conditions: Ketogenic Dieting
Interventions: OTHER: Low carb high fat ketogenic dieting|OTHER: Low carb high fat non-ketogenic dieting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Safety, Toleration And Pharmacokinetics Of Single Oral Doses Of PF-03864086 In Healthy Male Subjects
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: PF-3864086|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: VNS Treatment|DEVICE: VNS Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: transcranial direct current stimulation|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular and Cortical Contributions to Transitions in Freezing of Gait in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: EVS and EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Lapaquistat Acetate on Blood Cholesterol Levels in Treating Subjects With Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Classification of Abnormal Placentation
Status: UNKNOWN
Conditions: Adherent Placenta
Interventions: DEVICE: Trans- abdominal sonography|DEVICE: Trans-vaginal sonography|PROCEDURE: post-operative pathological specimen examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy and Safety of Lumbar MSAT on Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Lumbar motion style acupuncture treatment|PROCEDURE: Korean medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury
Interventions: DEVICE: Active High-definition transcranial direct current stimulation (HD-tDCS)|DEVICE: Sham High-definition transcranial direct current stimulation (HD-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients
Status: UNKNOWN
Conditions: Blunt Thoracic Injury|Lung Ultrasound Score
Interventions: DEVICE: high-flow nasal cannula|DEVICE: Conventional oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Abdominal Massage on Prevention of Recurrent Common Bile Duct Stones After Endoscopic Sphincterotomy
Status: RECRUITING
Conditions: Common Bile Duct Stone|Abdominal Massage
Interventions: BEHAVIORAL: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Versus Vaginal Hysterectomy in Women With Abnormal Uterine Bleeding Using Bipolar Vessel Sealer
Status: COMPLETED
Conditions: Uterine Bleeding
Interventions: PROCEDURE: Vaginal hysterectomy|PROCEDURE: Laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia
Status: COMPLETED
Conditions: Xerostomia|Head and Neck Cancers
Interventions: DRUG: mixed powder of A. digitata and M. sylvestris|DRUG: Hypozalix spray (artificial saliva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Melatonin on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Peritoneal Dialysis
Interventions: DIETARY_SUPPLEMENT: Melatonin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
Status: NOT_YET_RECRUITING
Conditions: Manual Pressure|Repositioning|Colonoscopy|Colon Polyp
Interventions: DEVICE: CO2 insufflation with an abdominal compression device|DEVICE: CO2 insufflation with a sham abdominal compression device|DEVICE: Water exchange colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Mediterranean Diet on Obstructive Sleep Apnoea-Hypopnoea Syndrome: A Randomised Trial
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea|Hypopnoea Syndrome
Interventions: BEHAVIORAL: Prudent diet group|BEHAVIORAL: Mediterranean diet group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Placebo|DRUG: Teduglutide 0.05 mg/kg/d|DRUG: Teduglutide 0.1 mg/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 Treatment for Wiskott-Aldrich Syndrome
Status: COMPLETED
Conditions: Wiskott-Aldrich Syndrome (WAS)|X-linked Thrombocytopenia
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Efficiency of Atraumatic Orogastric Tube Insertion Protocol With Combination of Wrapping, Fetal Position, Breastmilk, and Sucrose
Status: COMPLETED
Conditions: Premature|Orogastric Tube|Oral Sucrose
Interventions: OTHER: Wrapping + Breastmilk Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of TeaRx Xa Factor Direct Inhibitor Versus Enoxaparin as a Venous Thromboembolic Events (VTE) Prevention Following Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DRUG: TeaRx|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DM-IMT - Controlled, Randomized, Three-arm Intervention Study on the Safety and Efficacy of Regular Respiratory Muscle Training in Patients With Myotonic Dystrophy Type 1
Status: COMPLETED
Conditions: Myotonic Dystrophy 1
Interventions: DEVICE: IMT - inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Rituximab (MabThera) Subcutaneous (SC) Versus Rituximab (MabThera) Intravenous in Participannts With Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Rituximab SC|DRUG: Rituximab IV|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone/Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Orotic Acid Derivatives With or Without Glutathione on Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Orotic acid and Glutathione-(Nutritional Supplements)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy
Status: RECRUITING
Conditions: Radiculopathy Lumbar|Radiculopathy Sacral|Radiculopathy Multiple Sites
Interventions: DEVICE: Neubie Direct Current Electrical Stimulation Device|DEVICE: Transcutaneous Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT