pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Central and Eastern European Survey On PEEP Titration and Alveolar Recruitment Manoeuvres During Surgery
Status: COMPLETED
Conditions: Ventilator-Induced Lung Injury|Positive End-Expiratory Pressure|Alveolar Recruitment Manoeuvres
Interventions: OTHER: Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Avelumab, Cetuximab, and Palbociclib in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Avelumab|DRUG: Palbociclib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mobile Communication With a Cellular Phone With a Glucometer on Glucose Control in Type 2 Diabetic Patients
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: telecommunication based glucose monitoring system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Varenicline on Cognition, Safety, Tolerability and Pharmacokinetics in Subjects With Mild-to-Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Individual Variants of Agonist-antagonist and Traditional Agonistic Resistance Training on Cardiovascular Parameters
Status: ACTIVE_NOT_RECRUITING
Conditions: Arterial Stiffness|Hypertension|Cardiovascular Diseases
Interventions: BEHAVIORAL: Cardiovascular fitness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Genistein as a Possible Treatment for Alzheimer's Disease.
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DIETARY_SUPPLEMENT: Genistein|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison Between Spironolactone and Indapamide Monotherapy or in Combination With Amlodipine to Reduce the Risk of Heart Failure
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Spironolactone|DRUG: Indapamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Induction Methods in Premature Rupture of Membranes
Status: UNKNOWN
Conditions: Preterm Premature Rupture of Fetal Membranes|Induction of Labor Affected Fetus / Newborn
Interventions: DEVICE: Foley balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|B-cell Acute Lymphoblastic Leukemia|Large B-cell Lymphoma|Mantle Cell Lymphoma|Indolent Lymphoma|Waldenstrom Macroglobulinemia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Aggressive Lymphoma|Large-cell Lymphoma
Interventions: BIOLOGICAL: NKX019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Lanthanum Carbonate|DIETARY_SUPPLEMENT: NeutraPhos|OTHER: Diet Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria in Saliva and Bioaerosol Contamination
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Peroxyl Mouthwash|DRUG: Placebo Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteer|Weight Gain|Metabolic Effects|Integrase Strand Transfer Inhibitors
Interventions: DRUG: Tenofovir alafenamide|DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of PONV
Status: COMPLETED
Conditions: PONV|Palonosetron|Anesthesia
Interventions: DRUG: Palonosetron|DRUG: sevoflurane|DRUG: remifentanil|DRUG: pentothal sodium|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Postural Adjustment on Hemodynamics in Patients Undergoing Prone Spine Surgery Under General Anesthesia
Status: RECRUITING
Conditions: Asana Adjustment
Interventions: BEHAVIORAL: Asana adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant Prostate Cancer Progressing on Abiraterone
Status: WITHDRAWN
Conditions: Prostate Cancer|Castrate Resistant Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Sodium Selenite|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Effect on Pain and Edema Following Mandibular 3rd Molar Surgery; Pre-operatively vs Post-operatively
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Dexamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PsA T2T Statin Trial on Carotid and Coronary Atherosclerosis
Status: WITHDRAWN
Conditions: Psoriatic Arthritis|Atherosclerosis
Interventions: DRUG: Rosuvastatin|OTHER: Treat-to-target strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes
Status: RECRUITING
Conditions: Myocardial Infarction|Acute Coronary Syndrome|Diabetes|Ventricular Dysfunction
Interventions: DRUG: Placebo|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intensive Locoregional Chemoimmunotherapy for Recurrent Ovarian Cancer Plus Intranodal DC Vaccines
Status: RECRUITING
Conditions: Cancer of Ovary|Cancer of the Ovary|Neoplasms, Ovarian|Ovarian Cancer|Ovary Cancer|Ovary Neoplasms
Interventions: BIOLOGICAL: Cisplatin + celecoxib + DC vaccine|BIOLOGICAL: Cisplatin + CKM + Celecoxib + DC Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Reversing Hepatic Fibrosis or Cirrhosis Related to Hepatitis B Virus and Finding Biomarkers
Status: UNKNOWN
Conditions: Hepatitis B|Liver Fibrosis
Interventions: DRUG: Entecavir 0.5 mg|DRUG: Anluohuaxian Pill 12g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: COVID-19|Extracorporeal Membrane Oxygenation Complication|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Extracorporeal membrane oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cancer Related Major Depression Treated With a Single Dose of Psilocybin
Status: RECRUITING
Conditions: MDD
Interventions: DRUG: psilocybin 25 mg sod|DRUG: psilocybin 1 mg sod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Rheumatoid Arthritis (RA) Patients to Compare Two Formulations of Adalimumab for Pharmacokinetic, Pharmacodynamic and Safety
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab, current formulation|BIOLOGICAL: Adalimumab, new formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Intervention Study of Health Coaching to Promote Diabetes Self-Care in the Community
Status: COMPLETED
Conditions: Diabetes Complications|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Telephone Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Biafine|DRUG: Polysporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 'Understanding the Electrophysiological Substrate Underlying Persistent Atrial Fibrillation Study II (USURP AF- Study II)'
Status: RECRUITING
Conditions: Atrial Fibrillation Mechanisms|Persistent Atrial Fibrillation|Substrate Ablation|Pulmonary Vein Isolation|Non-contact Mapping
Interventions: OTHER: Catheter ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintenance Treatment With Liposomal Doxorubicin (Caelyx) in Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation|Endometrial Mucinous Adenocarcinoma|Endometrial Squamous Cell Carcinoma|Recurrent Endometrial Clear Cell Adenocarcinoma|Recurrent Endometrial Endometrioid Adenocarcinoma|Recurrent Endometrial Serous Adenocarcinoma|Recurrent Endometrial Undifferentiated Carcinoma|Recurrent Uterine Corpus Cancer
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Cisplatin|RADIATION: Intensity-Modulated Radiation Therapy|RADIATION: Internal Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renin Angiotensin System Blockade in Renal Transplant Patients With Presence of PECs in Urine
Status: UNKNOWN
Conditions: Chronic Kidney Allograft Nephropathy
Interventions: DRUG: Valsartan 80Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women
Status: RECRUITING
Conditions: Mild Autonomous Cortisol Excess
Interventions: DRUG: Elagolix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Administration Method Study of Human Regular U-500 Insulin (LY041001) in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Human regular U-500 insulin (CSII)|DRUG: Human regular U-500 insulin (MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Rheumatoid Arthritis Patients Who Have Completed a Preceding Study With ABBV-105 Given Alone or in Combination With Upadacitinib
Status: TERMINATED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: Elsubrutinib|DRUG: Upadacitinib|DRUG: Placebo for elsubrutinib|DRUG: Placebo for upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Ascending Dose Study of GS 5885 in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: GS-5885|DRUG: Placebo|DRUG: GS-5885|DRUG: Placebo|DRUG: GS-5885|DRUG: Placebo|DRUG: GS-5885|DRUG: Placebo|DRUG: GS-5885|DRUG: Placebo|DRUG: GS-5885|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic and Epigenetic Mechanisms of Developing Gestational Diabetes Mellitus and Its Effects on the Fetus
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: OTHER: Life-style modification, insulin therapy if needed|OTHER: Life-style modification, insulin therapy if needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carboplatin in Treating Patients With Stage IC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Radiofrequency-assisted Hepatectomy on the Outcomes of HCC Patients With Cirrhosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: PROCEDURE: Radiofrequency-assisted Hepatectomy|PROCEDURE: Conventional Hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Lip Injections With Emervel Lips Lidocaine and Juvéderm Volbella With Lidocaine
Status: COMPLETED
Conditions: Lip Filler Injections
Interventions: DEVICE: Emervel Lips Lidocaine|DEVICE: Juvéderma Volbella with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Outcomes From Initial Maintenance Therapy With Fluticasone Propionate 250/Salmeterol 50 (FSC) or Tiotropium in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol 250µg/50µg (FSC)|DRUG: tiotropium bromide (TIO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Occupational Therapy Modulates the Pain in Cancer Patient Under Palliative Care
Status: COMPLETED
Conditions: Cancer|Terminal Disease|Pain
Interventions: OTHER: Tapestry|OTHER: Regular occupation therapy|OTHER: Weaving a scarf on a nail frame|OTHER: Domino game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
Status: NOT_YET_RECRUITING
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: TFC-003|DRUG: COSOPT ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TS-1 Plus Cisplatin in Patients With Advanced Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer (NSCLC)
Interventions: DRUG: TS-1/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy and Safety of QGE031 in Adolescent Patients With Chronic Spontaneous Urticaria (CSU)
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Ligelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin|DRUG: Empagliflozin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)
Status: COMPLETED
Conditions: Graft-versus-host Disease (GVHD)
Interventions: DRUG: Ruxolitinib|DRUG: Prednisone or methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma
Status: WITHDRAWN
Conditions: Asthma|Airway Inflammation|Airflow Obstruction|Airway Hyperactivity
Interventions: DRUG: Pioglitazone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)
Status: TERMINATED
Conditions: Hypercholesterolemia|Atherosclerosis|Coronary Artery Disease
Interventions: DRUG: Rosuvastatin|DRUG: Ezetimibe + Atorvastatin|DRUG: Double Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endourage Complete Spectrum Oral Mucosal Drops (OMD) in Adults Desiring a Reduction in Ethanol Use
Status: WITHDRAWN
Conditions: Alcohol Drinking|Alcohol Use, Unspecified|Alcohol Abstinence|Alcohol-Related Disorders
Interventions: DIETARY_SUPPLEMENT: Endourage 1200 mg OMD ™ Oral Mucosal Drops|DIETARY_SUPPLEMENT: Isolate|OTHER: Placebo|DIETARY_SUPPLEMENT: Peppermint Oil, masking flavor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose-finding Study of Dalotuzumab in Subjects With Advanced Solid Tumors (MK-0646-002)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: dalotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Extracorporeal CO2 Removal in Case of Moderate to Severe ARDS to Apply an Ultraprotective Mechanical Ventilation Strategy
Status: RECRUITING
Conditions: Acue Respiratory Distress Syndrome
Interventions: PROCEDURE: High-flow extracorporeal CO2 removal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Adjunctive Treatments in Arthroscopic Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Bone Trephination|PROCEDURE: Soft Tissue Trephination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Outcomes of Recombinant Von Willebrand Factor on Demand Treatment and Prevention and Treatment of Bleeding During and After Surgery in Adults With Inherited Von Willebrand Disease in the United Kingdom (UK)
Status: COMPLETED
Conditions: Von Willebrand Disease (VWD)
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dexamethasone|OTHER: Placebo|DRUG: Morphine|DRUG: Zofran|DRUG: Paracetamol|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center, Randomized, Open-Label, Parallel Group Study of a Vaginal Micronized Progesterone Tablet (Endometrin®) Compared to Crinone 8% Vaginal Gel in Female Patients Undergoing In-Vitro Fertilization (IVF)
Status: COMPLETED
Conditions: Fertility
Interventions: DRUG: Endometrin|DRUG: Endometrin|DRUG: Crinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Statins and CPAP in Adipose Tissue of OSA
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Atorvastatin|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effects of Loperamide (JNJ-289679) on Electrocardiogram Intervals in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Loperamide|OTHER: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS)
Status: COMPLETED
Conditions: Ascites|Liver Cirrhosis
Interventions: DRUG: Satavaptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block for Abdominoplasty
Status: COMPLETED
Conditions: Pain, Postoperative|Abdominoplasty
Interventions: PROCEDURE: QL-block|DRUG: Ropivacaine|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation
Status: SUSPENDED
Conditions: Obesity|Weight Loss|Body Weight|Hepatocellular Carcinoma|HCC|Hepatitis C|Cirrhosis
Interventions: DEVICE: Embospheres Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of the Use MD Tissue Collagen Medical Device in the Infiltrative Treatment of Greater Trochanter Pain Syndrome (GTPS)
Status: TERMINATED
Conditions: Greater Trochanteric Pain Syndrome|GTPS - Greater Trochanteric Pain Syndrome|Tendon Disorder|Pertrochanteric Fracture|Gluteal Tendinitis|Gluteal Muscles
Interventions: DEVICE: MD Tissue Collagen Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sustained-Release Desvenlafaxine Hydrochloride for the Treatment of Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Sustained-Release Desvenlafaxine Hydrochloride|DRUG: Sustained-Release Venlafaxine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Status: SUSPENDED
Conditions: High Grade Osteosarcoma|Localized Osteosarcoma|Metastatic Osteosarcoma|Secondary Osteosarcoma
Interventions: PROCEDURE: Bone Scan|DRUG: Cabozantinib S-malate|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Doxorubicin Hydrochloride|PROCEDURE: Magnetic Resonance Imaging|DRUG: Methotrexate|PROCEDURE: Surgical Procedure|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PVI Based Intraoperative Fluid Management in Head and Neck Free Flap Reconstructive Surgeries
Status: COMPLETED
Conditions: Free Tissue Flaps
Interventions: OTHER: Group G -PVI( Masimo co oximeter) guided fluid therapy|OTHER: Group B- Body weight guided intravenous fluid @6-8ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies
Status: COMPLETED
Conditions: Prematurity|Intestine Perforation|Necrotizing Enterocolitis (NEC)|Short Bowel Syndrome (SBS)
Interventions: DIETARY_SUPPLEMENT: Microlipid with fish oil|DIETARY_SUPPLEMENT: Microlipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Safety, Tolerability, and Pharmacokinetics of MEDI0382 in Non-diabetic Obese Participants
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: MEDI0382|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Mirabilis High-Intensity Focused Ultrasound System for Non-Invasive Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids (Leiomyomas)
Interventions: DEVICE: Mirabilis High-Intensity Focused Ultrasound Treatment System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-management Support for Colorectal Cancer Survivors Colorectal Cancer Survivors: A Mixed-methods Study
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: colorectal cancer self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment
Status: COMPLETED
Conditions: Sleep Disorders, Circadian Rhythm|Sleep Disorder|Acceptability|Feasibility|Adaptation|Implementation Research
Interventions: BEHAVIORAL: Fitted Transdiagnostic Sleep and Circadian intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK0683 in Patients With Advanced Cancer (0683-008)
Status: COMPLETED
Conditions: Cancer, Advanced
Interventions: DRUG: vorinostat (MK0683 )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotic and Prebiotic Use on Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Prebiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of a Fully Automated Pulsating Support System (CuroCell® A4 CX20) in Pressure Ulcer Prevention and Treatment
Status: COMPLETED
Conditions: Pressure Ulcer|Pressure Injury|Pressure Sore|Pressure Ulcer, Buttock
Interventions: DEVICE: 22 residentsat risk for PU development|DEVICE: 18 residents at least one PU category III-IV in the sacral area
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DORAYA-HF OUS Assessment of the Doraya Catheter for the Treatment of ADHF Patients With Insufficient Response to Diuretics
Status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Interventions: DEVICE: Doraya catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mobile Health on Frailty, Muscle Strength and Health Literacy of the Elderly
Status: COMPLETED
Conditions: Telemedicine|Elderly|Health Literacy
Interventions: COMBINATION_PRODUCT: mobile health combined Multi-course Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS)
Status: COMPLETED
Conditions: Guillain Barre Syndrome
Interventions: DRUG: IVIG|PROCEDURE: Plasma Exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehab and Cerebral Blood Flow Study
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Cardiac rehabilitation - high intensity interval training (HIIT)|BEHAVIORAL: Cardiac rehabilitation - moderate intensity continuous training (MICT)|BEHAVIORAL: Cardiac rehabilitation - control|BEHAVIORAL: Cardiac rehabilitation - observational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prediction of Fluid Responsiveness in Atrial Fibrillation Patients Who Underwent Valvular Heart Surgery: Peep-induced Increase in Central Venous Pressure vs. Passive Leg Raising
Status: COMPLETED
Conditions: Valvular Heart Surgery
Interventions: PROCEDURE: peep induced CVP|PROCEDURE: passive leg raising(PLR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Forging Hopeful Futures to Reduce Youth Violence
Status: RECRUITING
Conditions: Violence in Adolescence|Racism|Adolescent Behavior|Coping Skills|Communication, Social|Communication, Personal|Violence, Sexual|Violence, Non-accidental|Violence, Physical|Violence, Gender-Based
Interventions: BEHAVIORAL: Forging Hopeful Futures|BEHAVIORAL: Wellness Check-ins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase Ⅲ Clinical Study of Quadrivalent Influenza Virus Split Vaccine
Status: COMPLETED
Conditions: Prevention of Influenza
Interventions: BIOLOGICAL: Investigational Vaccine(0.25ml/vial)|BIOLOGICAL: Investigational Vaccine(0.5ml/vial)|BIOLOGICAL: Active compared Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation
Status: RECRUITING
Conditions: Cancer Screening
Interventions: BEHAVIORAL: Patient Navigation (PN) - More Intensive|BEHAVIORAL: Educational Materials|BEHAVIORAL: Patient Navigation (PN) - Less Intensive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A 12-week Digital Physical Activity Programme, With or Without Physical Education Support for Type 2 Diabetes Patients.
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: HbA1c testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Linagliptin on Renal Endothelium Function in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Type 2-diabetes
Interventions: DRUG: Linagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Oral Asciminib (ABL001) in Patients With CML or Ph+ ALL
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia|Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Asciminib (ABL001)|DRUG: Nilotinib|DRUG: Imatinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Implant Stability Using Two Accepted Techniques for Implant Sites
Status: COMPLETED
Conditions: Implant
Interventions: PROCEDURE: Preparing the osteotomy to accept a standard implant device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Computed Tomography|RADIATION: Image Guided Radiation Therapy|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia, Progressive|Myopia
Interventions: DEVICE: Test myopia control lenses|DEVICE: Single vision lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery
Status: COMPLETED
Conditions: Primary Open-angle Glaucoma
Interventions: DEVICE: iStent supra|PROCEDURE: Cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Handbook for Parents of Children Newly Diagnosed With Food Allergy
Status: COMPLETED
Conditions: Hypersensitivity, Food
Interventions: OTHER: Food allergy handbook for parents|OTHER: Food allergy treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Appropriate Prescribing for Older Adults With Multimorbidity (Pro-M)
Status: COMPLETED
Conditions: Potentially Inappropriate Medications|Multimorbidity|Polypharmacy
Interventions: OTHER: Medication review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS
Status: UNKNOWN
Conditions: Oligoarthritis, Juvenile|Polyarthritis, Juvenile, Rheumatoid Factor Negative
Interventions: DRUG: Etanercept|DRUG: Methotrexate|DRUG: Intra-articular corticosteroid injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Trimethoprim/Sulfamethoxazole as PCP Prophylaxis in CTD Patients
Status: UNKNOWN
Conditions: Pneumonia, Pneumocystis|Prevention & Control
Interventions: DRUG: Trimethoprim/Sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Culturally Grounded, Trauma-Informed Alcohol Intervention With a Reserve-Dwelling First Nation Group
Status: NOT_YET_RECRUITING
Conditions: Alcohol Drinking|Trauma, Psychological|Historical Trauma
Interventions: BEHAVIORAL: Native HEALTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine-induced Killer Cell Immunotherapy for Surgical Resected Stage III Colorectal Cancer Patients After Chemotherapy
Status: UNKNOWN
Conditions: Stage III Colon Cancer
Interventions: PROCEDURE: Radical surgery|DRUG: Adjuvant chemotherapy|BIOLOGICAL: Cytokine-induced killer cell immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Cryoablation for Palliation of Painful Bone Metastases
Status: COMPLETED
Conditions: Pain|Neoplasm Metastasis|Bone Metastasis of Diverse Origins
Interventions: DEVICE: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A for Emotional Stabilization in Borderline Personality Disorder (BPD)
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: incobotulinumtoxin A|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder
Status: TERMINATED
Conditions: Opioid-use Disorder
Interventions: DRUG: Buprenorphine|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dried Plums and Bone Health in Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Postmenopausal Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Dried Plum|DIETARY_SUPPLEMENT: Calcium supplement|DIETARY_SUPPLEMENT: Vitamin D supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Gastrointestinal Comfort Following Regular Consumption of Short-chain Fructo-oligosaccharides (10-20 g Per Day) by Children Aged 6-12 Years
Status: COMPLETED
Conditions: Gastrointestinal Tract
Interventions: DIETARY_SUPPLEMENT: short-chain fructo-oligosaccharides (dose 1)|DIETARY_SUPPLEMENT: short-chain fructo-oligosaccharides (dose 2)|OTHER: Baseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of rhTPO and Eltrombopag in Patients With Primary Immune Thrombocytopenia (ITP)
Status: UNKNOWN
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: rhTPO|DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Narrow Angles - Laser Iridotomy Study; Multicentric RCT
Status: UNKNOWN
Conditions: Asymptomatic Narrow Angles|Primary Angle Closure Suspects
Interventions: PROCEDURE: Laser Peripheral Iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ABT-378/Ritonavir in Combination With Reverse Transcriptase Inhibitors in Antiretroviral Naïve HIV-Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mulligan'Mobilization With Movement on Pain, Disability and Range of Motion in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Physical Fittness
Interventions: PROCEDURE: joint mobilization with movement|PROCEDURE: traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intron A for the Treatment of Hypertrophic Scar
Status: WITHDRAWN
Conditions: Burn|Hypertrophic Scar
Interventions: DRUG: interferon alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurodevelopmental Outcome After Prenatal Anesthesia
Status: COMPLETED
Conditions: Neurodevelopmental Disorders|Child Behavior
Interventions: OTHER: Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF)|OTHER: Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Taylor's Approach vs Lumbar Approach for Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: PROCEDURE: Lumbar paramedian approach at L3-L4 interspace|PROCEDURE: Taylor's approach (paramedian approach at L5-S1 interspace)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Angio-based Final Functional Effect of PCI
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Non ST Segment Elevation Acute Coronary Syndrome|Chronic Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: Angiography-based vessel fractional flow reserve (vFFR) calculation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance and Safety of a Second Generation Antimicrobial Graft in Abdominal Position
Status: COMPLETED
Conditions: Abdominal Aorta Aneurysm
Interventions: DEVICE: Intergard Synergy Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Diclofenac Sodium Gel in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteearthritis
Interventions: DRUG: Diclofenac Topical Sodium Gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm|Pain
Interventions: DRUG: Pamidronate|DRUG: Zoledronic acid|RADIATION: Sm 153 lexidronam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study Of A Monoclonal Antibody Against A5B1 Integrin In Solid Tumors
Status: TERMINATED
Conditions: Advanced Non-Hematologic Malignancies
Interventions: DRUG: PF-04605412
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patients
Status: WITHDRAWN
Conditions: Pulmonary Aspergillosis - Invasive|Acute Myeloid Leukemia
Interventions: DRUG: F901318|DRUG: Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ulipristal Acetate 10 mg and Asisted Reproduction
Status: TERMINATED
Conditions: Intramural Fibroids|Uterine Fibroids
Interventions: DRUG: Ulipristal Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Atomoxetine on ADHD-Related Insomnia in Children and Adolescents
Status: UNKNOWN
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)|Insomnia
Interventions: DRUG: atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intra-Osseous Co-Transplant of UCB and hMSC
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myelogenous Leukemia|Myelodysplastic Syndromes|Myelofibrosis|Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Relapsed Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Lymphoid Malignancies|Chronic Myelogenous Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|RADIATION: total-body irradiation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|PROCEDURE: mesenchymal stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung-MAP: AZD4547 as Second-Line Therapy in Treating FGFR Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer
Status: COMPLETED
Conditions: FGFR1 Gene Amplification|FGFR1 Gene Mutation|FGFR2 Gene Amplification|FGFR2 Gene Mutation|FGFR3 Gene Amplification|FGFR3 Gene Mutation|Recurrent Squamous Cell Lung Carcinoma|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: DRUG: Docetaxel|DRUG: FGFR Inhibitor AZD4547|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects on Glycemic and Insulinemic Responses by Fruit Consumption
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Test 1|OTHER: Test 2|OTHER: Test 3|OTHER: Test 4|OTHER: Test 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER