pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exploration of the Appropriate Combination of Positive End Expiratory Pressure and Tidal Volume Using the Intratidal Compliance Volume Profile in Children
Status: COMPLETED
Conditions: Respiratory Compliance
Interventions: OTHER: Changes in positive end-expiratory pressure and tidal volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Flavopiridol in Treating Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-cell Chronic Lymphocytic Leukemia|Refractory Chronic Lymphocytic Leukemia|Stage I Chronic Lymphocytic Leukemia|Stage II Chronic Lymphocytic Leukemia|Stage III Chronic Lymphocytic Leukemia|Stage IV Chronic Lymphocytic Leukemia
Interventions: DRUG: alvocidib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DRUG: SkQ1 Vehicle Solution|DRUG: SkQ1 Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Comparison of Pioglitazone and Glyburide in Type 2 Diabetes Subjects With Mild to Moderate Congestive Heart Failure
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: Pioglitazone|DRUG: Glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IDA (Immunothérapie de la Dermatite Atopique) Adult - Immunotherapy in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: ROUVAX|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Suture of the Ovary After Enucleation of Ovarian Endometrioma
Status: NOT_YET_RECRUITING
Conditions: Endometrioma
Interventions: PROCEDURE: Suture of the ovarian cortex|PROCEDURE: No suture of the ovarian cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial on Oral Miltefosine in Comparison With Glucantime in the Treatment of ACL Caused by L. Tropica
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Miltefose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DMPA & High Dose Oral Progestin (MPA) Tablets in Outpatient Treatment of Acute Excessive Vaginal Bleeding
Status: COMPLETED
Conditions: Dysfunctional Uterine Bleeding
Interventions: DRUG: Medroxyprogesterone 17-Acetate|DRUG: medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: 3-D Conformal Radiation Therapy|RADIATION: Intensity Modulated Radiation Therapy|DRUG: Casodex, Zoladex , Lupron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Survey Among Healthcare Professionals Treating Patients With Metastatic Breast Cancer in Selected European Countries to Evaluate Their Knowledge on Management of Hyperglycemia When Using Alpelisib
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Piqray Prescriber's/HCP guide for hyperglycemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of The Effects of Concentric And Eccentric Isokinetic Exercises in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: the concentric isokinetic exercise group|OTHER: the eccentric isokinetic exercise group|OTHER: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine vs Peripheral Nerve Block
Status: TERMINATED
Conditions: Pain, Acute|Surgery|Anesthesia|Opioid Use
Interventions: DRUG: Liposomal bupivacaine|DRUG: Peripheral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study Comparing the Effects of Subcutaneous Epoetin Hospira and Epoetin Alfa [Epogen] (Amgen) in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
Status: COMPLETED
Conditions: Chronic Renal Failure|Chronic Kidney Disease
Interventions: BIOLOGICAL: Epoetin Hospira|BIOLOGICAL: Epogen Amgen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib in Patients With Progressive Recurrent and/or Metastatic Salivary Gland Carcinoma
Status: COMPLETED
Conditions: Salivary Gland Carcinoma
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Optimal Antibiotic Treatment Duration for Community-acquired Pneumonia in Adults Diagnosed in General Practice in Denmark (CAP-D)
Status: RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Phenoxymethylpenicillin 1.2 MIE 4 times daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lower Fluorescein Sodium Dose on Confocal Laser Endoscopy Image Quality and Yellow Discoloration of the Skin
Status: UNKNOWN
Conditions: Image Quality|Skin Discoloration
Interventions: DRUG: fluorescein sodium 0.01ml/kg|DRUG: fluorescein sodium 0.02ml/kg|DRUG: fluorescein sodium 0.05ml/kg|DRUG: fluorescein sodium 0.1ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Dexamethasone|BIOLOGICAL: EBV-specific cytotoxic T lymphocytes|BIOLOGICAL: G-CSF or Peg-GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)
Status: TERMINATED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Post-traumatic Arthritis
Interventions: PROCEDURE: Navigated TKA with a minimally invasive approach|PROCEDURE: Navigated TKA with a conventional approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collecting and Storing Blood Samples From Patients With Cancer
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Nonmalignant Neoplasm|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intermittent Oro-esophageal Tube on Rehabilitation Therapy Compliance for Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Dasatinib in Advanced Sarcomas
Status: COMPLETED
Conditions: Rhabdomyosarcoma|Malignant Peripheral Nerve Sheath Tumors|Chondrosarcoma|Sarcoma, Ewing's|Sarcoma, Alveolar Soft Part|Chordoma|Epithelioid Sarcoma|Giant Cell Tumor of Bone|Hemangiopericytoma|Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Intranasal Ketamine Related Changes in Attentional Brain Networks With Functional and Structural MRI
Status: COMPLETED
Conditions: Ketamine Treatment
Interventions: DRUG: 56mg esketamine (2x Spravato® 28 mg nasal spray)|DRUG: 0.9% saline solution nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Retain Your Brain Health Study (RetainYourBrain.Com)
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Dementia|Healthy Participants|Brain Health
Interventions: BEHAVIORAL: Brain Health Education|BEHAVIORAL: Alzheimer Disease Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy
Status: TERMINATED
Conditions: Multiple Brain Metastases
Interventions: DRUG: BMX-001|RADIATION: Whole Brain Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Rhamnosus GG Oral Treatment Efficacy on Vernal Keratoconjunctivitis Treatment
Status: COMPLETED
Conditions: Vernal Keratoconjunctivitis
Interventions: DRUG: Lactobacillus Rhamnosus GG|DRUG: placebo (sugar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Ticagrelor With Aspirin for Prevention of Vascular Events in Patients Undergoing CABG
Status: TERMINATED
Conditions: Coronary Artery Disease|Stable Angina|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor|DRUG: Aspirin|DRUG: Placebo - Ticagrelor|DRUG: Placebo - Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Management Training for Latinas Receiving Chemotherapy
Status: COMPLETED
Conditions: Cancer|Stress
Interventions: BEHAVIORAL: Spanish-Language Self-Administered Training Plus Usual Care (SL-SAT)|BEHAVIORAL: Usual Care Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daratumumab-SC for Highly Sensitized Patients Awaiting Heart Transplantation
Status: COMPLETED
Conditions: Allosensitization|Heart Transplant Failure and Rejection
Interventions: DRUG: Daratumumab-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-1004-1239|OTHER: Placebo|DRUG: ACT-1004-1239 (Food-effect subpart)|OTHER: Placebo (Food-effect subpart)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent
Status: COMPLETED
Conditions: Endometriosis
Interventions: OTHER: Susceptibility Weighted Imaging as 3D SWAN sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association Between Training Load and Lactate and Other Metabolites Analyzed by Metabolomic and Proteomic Techniques
Status: NOT_YET_RECRUITING
Conditions: Lactate|Sports Performance|Metabolomics|Proteomics
Interventions: OTHER: Single basketball training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acceptance-based Behavioral Treatment for Obesity: Maintenance and Mechanisms
Status: COMPLETED
Conditions: Acceptance-based Treatment|Standard Behavioral Treatment
Interventions: BEHAVIORAL: Acceptance-based treatment|BEHAVIORAL: Standard behavioral treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Hormone Receptor Positive Breast Carcinoma|Locally Advanced Breast Carcinoma|Metastatic Breast Carcinoma|Metastatic Endometrioid Adenocarcinoma|Metastatic Fallopian Tube Carcinoma|Metastatic HER2 Negative Breast Carcinoma|Metastatic Malignant Solid Neoplasm|Metastatic Ovarian Carcinoma|Metastatic Primary Peritoneal Carcinoma|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Refractory Breast Carcinoma|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Stage IVA Fallopian Tube Cancer AJCC v8|Stage IVA Ovarian Cancer AJCC v8|Stage IVA Primary Peritoneal Cancer AJCC v8|Stage IVA Uterine Corpus Cancer AJCC v8|Stage IVB Fallopian Tube Cancer AJCC v8|Stage IVB Ovarian Cancer AJCC v8|Stage IVB Primary Peritoneal Cancer AJCC v8|Stage IVB Uterine Corpus Cancer AJCC v8
Interventions: DRUG: Abexinostat Tosylate|DRUG: Fulvestrant|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Client-Centered Intervention inTotal Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: BEHAVIORAL: traditional occupational therapy intervention and client-centered intervention|BEHAVIORAL: Traditional occupational therapy intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Laparoscopic Truncal Vagotomy for the Treatment of Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic Truncal Vagotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Recurrent or Persistent Cancer of the Uterus
Status: COMPLETED
Conditions: Recurrent Uterine Corpus Sarcoma|Uterine Corpus Leiomyosarcoma
Interventions: DRUG: Thalidomide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Occlutech Septal Occluder (Figulla Flex II) Study
Status: COMPLETED
Conditions: Secundum Atrial Septal Defects
Interventions: DEVICE: transcatheter closure of secundum atrial septal defects in patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Extended Release Bupivacaine for Pain Relief After Surgery
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: SABER-Bupivacaine (Part 1)|DRUG: SABER-Bupivacaine (Part 2)|DRUG: Saline Placebo|DRUG: Bupivacaine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride
Status: SUSPENDED
Conditions: Aortic Aneurysm, Thoracic
Interventions: DRUG: Pimonidazole hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Affective Responses Following Aerobic Exercise With Different Intensities
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Affective response MIT|BEHAVIORAL: Affective response HAIT|BEHAVIORAL: Affective response HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Capnography Monitoring in Ventilated Children
Status: UNKNOWN
Conditions: Child, Only|Infant, Newborn, Diseases|Critical Illness|ARDS, Human|Heart Defects, Congenital|Lung Diseases, Obstructive|Lung Diseases, Interstitial
Interventions: DIAGNOSTIC_TEST: capnography monitoring|DIAGNOSTIC_TEST: arterial blood gas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Right Sided Colon Polyp Miss Rate: Impact Of Retroflexion In The Right Colon
Status: UNKNOWN
Conditions: Colon Polyps|Colon Cancer Screening
Interventions: PROCEDURE: Retroflexion in the right colon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Gall Bladder Bed Infiltration Analgesia
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: the infiltration group|DRUG: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Colchicine in Preventing Recurrent Stroke in the Patients With Acute Atherothrombotic Ischemic Stroke During Hospitalization
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Colchicine|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of MLN0002 (300 mg) in Treatment of Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Vedolizumab|DRUG: Vedolizumab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective Tissue Disorders (CTD)
Status: COMPLETED
Conditions: Interstitial Lung Disease|Connective Tissue Diseases
Interventions: BIOLOGICAL: Allogeneic Bone Marrow Derived Mesenchymal Stem Cells (BMD-MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Of Cervical Rehabilitation Program After Thyroidectomy
Status: COMPLETED
Conditions: Post-Thyroidectomy Hypoparathyroidism
Interventions: OTHER: Cervical Rehabilitation program (Intervention Group) Group A|OTHER: control group group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Abatacept Effectiveness in Differential Treatment of Interstitial Lymphocytic Lung Disease in Children With Primary Immunodeficiencies.
Status: UNKNOWN
Conditions: Interstitial Lymphocytic Lung Disease
Interventions: DRUG: Rituximab|DRUG: Abatacept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REducing Sympathetic Activity Through Ultrasound-based Renal deneRvation in Excessive Cardiovascular Risk populaTions.
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Heart Failure|End Stage Renal Disease
Interventions: DEVICE: Renal Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Mitomycin-c 40mg/20ml and Gemcitabine 2000mg/50ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy
Status: COMPLETED
Conditions: Esophagogastroduodenoscopy
Interventions: DRUG: Meperidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pectoralis Minor Shorthening and Swimming Performance
Status: COMPLETED
Conditions: The Study Will Not be Based on Any Disease|Ability to Swim 100m Independent Freestyle|Be Between the Ages of 9-16|Continuing Running as Part of a Sports Club
Interventions: BEHAVIORAL: pektoralis minor shortnes|BEHAVIORAL: Group in which the Pectoralis Minor stretching exercise was performed in a sham manner|BEHAVIORAL: The group in which Pectoralis Minor stretching exercise was not applied
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intraosseous Access
Status: COMPLETED
Conditions: Intraosseus Access|Manikin|Resuscitation
Interventions: DEVICE: NIO Adult device|DEVICE: Bone Iniection Gun|DEVICE: EZ-IO|DEVICE: Jamshidi Intraosseous Needle|DEVICE: Cook Intraosseous Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block for Gynaecological Laparotomies - a Comparison of Ultrasound-guided Block and Blind Technique
Status: COMPLETED
Conditions: Laparotomy
Interventions: PROCEDURE: Transversus abdominis plane (TAP) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Descriptive Study of Knee Joint Pain During Strength Training After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Knee extension strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Evaluate an Optimization Procedure of Alveolar Recruitment During Transport Performed by Nurse Anesthetists in Intensive Care
Status: COMPLETED
Conditions: Respiratory Complication
Interventions: PROCEDURE: Clamping of the ventilator endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Teaching Before or After Simulation Improve Learning?
Status: RECRUITING
Conditions: Medical Education|Simulation
Interventions: OTHER: Simulation on Pediatric Status Epilepticus|OTHER: Didactic Lecture on Pediatric Status Epilepticus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Transurethral Vapor Enucleation Resection of the Prostate (TVERP), Bipolar TURis and HoLEP
Status: TERMINATED
Conditions: Benign Prostatic Hypertrophy
Interventions: DEVICE: TVERP|DEVICE: TURis|DEVICE: HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days Treatment
Status: COMPLETED
Conditions: Peptic Ulcer
Interventions: DRUG: Ilaprazole|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal Carcinoma
Status: WITHDRAWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Fluviral® (2008 - 2009 Season) in Adults Over 18 Years
Status: COMPLETED
Conditions: Influenza Vaccines
Interventions: BIOLOGICAL: Fluviral®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and Neurological Effects of Dry Needling in the Treatment of Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Myofascial Pain Syndrome
Interventions: PROCEDURE: Dry needling|DEVICE: acupuncture needle 0,25 x 40mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established in Clinical Trial 38833 (P05783)
Status: COMPLETED
Conditions: Pregnancy|Neonates
Interventions: DRUG: Corifollitropin alpha (MK-8962, Org 36286) 100 ug|DRUG: Corifollitropin alpha (MK-8962, Org 36286) 150 ug|DRUG: Triptorelin|BIOLOGICAL: Recombinant follicle stimulating hormone (recFSH)|BIOLOGICAL: Human chorionic gonadotprophin (hCG).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Drug Resistant Epilepsy|Epilepsy|Epilepsy, Temporal Lobe
Interventions: DEVICE: Focused ultrasound (FUS) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Different Non-invasive Techniques to Monitor the Clearance of Actinic Keratosis Lesions
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aldara (Imiquimod)|OTHER: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Photo Avaluation
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINBACK (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Postoperative Vomiting
Interventions: DRUG: SB dexmedetomidine bupivacaine block|DRUG: intravenous dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial to Determine MTD of BI 836845 Administered Intravenously Once Every Three Weeks in Patients With Advanced Solid Tumours and Later a Weekly Dosing Schedule in Selected Tumour Types
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 836845
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nasal Naphazoline Hydrocloride + Pheniramine Maleate + Panthenol Compared With Naphazoline Hydrocloride in the Symptomatic Control of Nasal Congestion and Nasopharyngeal
Status: COMPLETED
Conditions: Flu|Cold|Allergic Disorder of Respiratory System
Interventions: DRUG: naphazoline hydrocloride|DRUG: Naphazoline hydrocloride + Pheniramine Maleate + Panthenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arachidonic Acid Supplementation in Very Preterm Infants
Status: COMPLETED
Conditions: Impaired Psychomotor Development
Interventions: DIETARY_SUPPLEMENT: Preterm infants formula A|DIETARY_SUPPLEMENT: Preterm infants formula B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies
Status: TERMINATED
Conditions: Tumor, Solid|Gastrointestinal Cancer
Interventions: DRUG: Ulixertinib|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
Status: TERMINATED
Conditions: Drug-Resistant Epilepsy|Focal-Onset Seizures
Interventions: DRUG: Padsevonil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project Matter: Intervention to Improve HIV Self-care Among Men Who Have Sex With Men (MSM) With Substance Use Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use Disorders|HIV/AIDS|Homosexuality, Male
Interventions: BEHAVIORAL: Project Matter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus Type 2 With Proteinuria|Diabetes Mellitus, Type 2|Diabetes Mellitus|Diabetes|Diabetes Complications|Albuminuria|Chronic Kidney Diseases|Chronic Kidney Disease Due to Type 2 Diabetes Mellitus|Chronic Kidney Disease stage3|Chronic Kidney Disease stage4|CKD|CKD Stage 3|CKD Stage 4
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Finerenone|DEVICE: Withings BPM Connect|DEVICE: Withings Body|DIAGNOSTIC_TEST: PeeSpot Urine Collection Device|DIAGNOSTIC_TEST: Hem-Col Capillary Blood Collection Device|BEHAVIORAL: Questionnaire: participants' perspectives toward the feasibility of participation in a trial at home with digital technologies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnotic Cognitive Therapy Reduce Acute & Chronic SCI Pain in Inpatient Rehabilitation
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries|Pain, Chronic|Spinal Cord Injury, Acute
Interventions: BEHAVIORAL: Hypnosis enhanced cognitive behavioral therapy|BEHAVIORAL: Pain Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Pigtail Catheter Drainage Versus Need Based Thoracocentesis for Recurrent Hepatic Hydrothorax.
Status: NOT_YET_RECRUITING
Conditions: Hepatic Hydrothorax
Interventions: PROCEDURE: Large Volume Thoracocentesis|PROCEDURE: Pigtail Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The ASSURE ROT Registry: Bioresorbable Vascular Scaffold Following Rotablation for Complex Coronary Lesions
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Coronary Artery Disease|Myocardial Ischemia|Coronary Disease|Coronary Restenosis|Heart Diseases|Coronary Stenosis|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metoclopramide as Treatment of Clozapine-induced Hypersalivation
Status: COMPLETED
Conditions: Clozapine-induced Hypersalivation
Interventions: DRUG: Metoclopramide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia With FLT3/ITD Mutation|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Sorafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outpatient Versus Inpatient Detoxification Program for Alcohol Dependent Patients Seeking Abstinence: The IN/OUT Study
Status: COMPLETED
Conditions: Alcoholism|Alcohol Dependence
Interventions: PROCEDURE: Outpatient detoxification program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Performance Evaluation of T-TAS 01 PL Chip
Status: COMPLETED
Conditions: Platelet Dysfunction|Von Willebrand Diseases|Healthy|Congenital Platelets Abnormality
Interventions: DIAGNOSTIC_TEST: T-TAS 01 PL Chip|DIAGNOSTIC_TEST: PFA-100 Col/Epi and Col/ADP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicentre European Study to Evaluate Granulox® Used in the Treatment Pathway of Predominantly Chronic Venous Leg Ulcers (VLUs).
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Venous Leg Ulcer Standard of Care with Granulox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics (PK) Study of a Fluconazole Loading Dose in Infants and Toddlers
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: Fluconazole Loading Dose|DRUG: Fluconazole Loading Dose & High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ketamine and Risperidone on Cognition
Status: COMPLETED
Conditions: Healthy Volunteers|Schizophrenia
Interventions: DRUG: ketamine|DRUG: risperidone|DRUG: saline|DRUG: placebo risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology
Status: ENROLLING_BY_INVITATION
Conditions: Sarcoma|Soft Tissue Sarcoma|Bone Sarcoma|Bone Metastases|Venous Thromboembolism|Hematoma|Anticoagulant-induced Bleeding
Interventions: DRUG: Aspirin 325mg|DRUG: Enoxaparin 40Mg/0.4mL Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types
Status: COMPLETED
Conditions: Sarcoma|Ovarian Neoplasm|Central Nervous System Neoplasm|Thyroid Neoplasm|Carcinoma, Neuroendocrine|Neoplasms, Germ Cell and Embryonal|NK/T-cell Lymphoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Resilience and Longevity for Workers Through Exercise
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: Exercise|OTHER: No Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccination of Metastatic Breast Cancer Patients With a CD80-modified Allogeneic Cancer Cell Line (KS2422)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: KS24.22 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard vs. Ultrasound-assisted Catheter Thrombolysis for Submassive Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: PROCEDURE: CDT without ultrasound acceleration|PROCEDURE: CDT with ultrasound acceleration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation on Safety and Efficacy of Soybean Fermented Extract (MBS217) in Treating Patients With NAFLD
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: MBS217|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Functional Electric Stimulation (FES)|BEHAVIORAL: Behavioral Assessments|OTHER: Magnetic Resonance Imaging|OTHER: EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders
Status: RECRUITING
Conditions: Acute Leukemia|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Lymphoma|Chronic Myelogenous Leukemia|Plasma Cell Leukemia|Myeloproliferative Neoplasms|Myelofibrosis|Myelodysplasia|Refractory Anemia|High Risk Anemia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Marginal Zone B-Cell Lymphoma|Follicular Lymphoma|Lymphoplasmacytic Lymphoma|Mantle-Cell Lymphoma|Prolymphocytic Leukemia|Diffuse Large Cell Non Hodgkins Lymphoma|Lymphoblastic Lymphoma|Burkitt Lymphoma|High Grade Non-Hodgkin's Lymphoma, Adult|Multiple Myeloma|Juvenile Myelomonocytic Leukemia|Biphenotypic/Undifferentiated/Prolymphocytic Leukemias|MRD Positive Leukemia|Natural Killer Cell Malignancies|Acquired Bone Marrow Failure Syndromes
Interventions: BIOLOGICAL: HSCT with TBI Regimen|BIOLOGICAL: HSCT with Non-TBI Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Combination With Temozolomide in Patients With Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Bevacizumab|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance With Gadoxetic Acid for the Diagnosis of Hepatocellular Carcinoma in Patients With Liver Cirrhosis. Evaluation of Its Impact for the Non-invasive Diagnosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: GADOXETIC ACID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Internet-based MOTOmed Exercise to Reduce Spasticity and Improve Physical Function in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Treatment group 1|BEHAVIORAL: Treatment group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: OTX-101 0.09%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vitro Study of the Biological and Immunological Activity of Imotopes® Candidates on Blood Cells of Patients With Stabilized NMO
Status: COMPLETED
Conditions: Neuromyelitis Optica
Interventions: PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Relugolix|DRUG: Estradiol/norethindrone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Numeris®-AF Guided Coagulation System with VisiTrax®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Software Treatment for Actively Reducing Severity of ADHD in Adolescents (STARS-ADHD-Adolescents)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: AKL-T01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study and Evaluate the Effectiveness of Treatment by Percutaneous Electrical NeuroStimulation (PENS) for Post-operative Pain in Cesarean Section Patients Using Primary Relief v 2.0
Status: UNKNOWN
Conditions: Cesarean Section; Dehiscence
Interventions: DEVICE: Primary Relief v 2.0|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Single Hormone Closed Loop Study With PDT Sensor
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Artificial Pancreas Control system (APC)|DEVICE: Pacific Diabetes Technologies CGM Insulin Infusion system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy of 3 Nutritional Supplements to Improve Diverse Outcomes in Children Under 2 Years of Age and Pregnant Women
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: fortified milk-based beverage|DIETARY_SUPPLEMENT: Sprinkles|DIETARY_SUPPLEMENT: tablets|DIETARY_SUPPLEMENT: Fortified milk-based pap|DIETARY_SUPPLEMENT: Sprinkles|DIETARY_SUPPLEMENT: Syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Virtual Reproduction of Mandibular Movement for Assessing Occlusal Interferences and Adjustments
Status: COMPLETED
Conditions: Dental Occlusion
Interventions: OTHER: CAD-CAM zirconia crowns using buccal interocclusal record.|OTHER: CAD-CAM zirconia crowns using lateral interocclusal records.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Étude de l'efficacité du Pansement Rigide Amovible Sous Vide à Titre de modalité de Pansement Post-amputation Tibiale
Status: UNKNOWN
Conditions: Trans-tibial Amputations
Interventions: DEVICE: Ossur Rigid Dressing|DEVICE: Elastic Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Semaglutide|DRUG: Firsocostat|DRUG: Cilofexor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis Patients
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis|Peritoneal Dialysis Complication|Sodium-glucose Cotransporter-2 Inhibitor|Residual Kidney Function
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery
Status: SUSPENDED
Conditions: Mandible; Deformity|Surgical Healing|Orthognathic Surgery|Nerve Injury
Interventions: DEVICE: Low-level laser therapy|DEVICE: Dummy LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Real-world Evidence to Analyze the Clinical Effects and Adverse Events of Butylphthalide in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Cerebral Infarction|Brain Infarction|Brain Ischemia|Nervous System Diseases|Central Nervous System Diseases|Vascular Diseases|Cardiovascular Diseases
Interventions: OTHER: butylphthalide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: iCanCope With Sickle Cell Pain
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Pain self-management|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Outcome Predictors and Stratification of Responder Profiles Implanted With Spinal Cord Stimulation. An AI-based-pathway & Algorithmic Approach to Treat Failed Back Surgery Syndrome Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Intractable
Interventions: DEVICE: Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING