pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: To Assess the Influence of Aronox on Parameters Associated With Recovery Following Muscle Damaging Exercise
Status: COMPLETED
Conditions: Muscle Damage
Interventions: DIETARY_SUPPLEMENT: 500mg of Aronox® >40% polyphenol aronia extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: BiventRicular Pacing in prolongEd Atrio-Ventricular intervaL: the REAL-CRT Study
Status: UNKNOWN
Conditions: First Degree Atrioventricular Block
Interventions: DEVICE: Cardiac resynchronization therapy pacemaker|DEVICE: Dual chamber pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Infarction With ST-Elevation
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Abciximab|DRUG: Abciximab placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact Evaluation of a Mobile Health App to Improve Self-control and Health Outcomes of Patients With Type 2 Diabetes Mellitus (T2DM): Pilot Study "NOVAME"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: mobile app NOVAME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Low Level Light Therapy on Histamine- and Mucuna Pruriens-induced Pruritus in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Low Level Light Therapy|DEVICE: Sham Controll
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)
Status: COMPLETED
Conditions: Renal Dialysis|Kidney Failure, Chronic
Interventions: DRUG: MK-2060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Liposomal Irinotecan|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deltoid Ligament Arthroscopic Repair in Ankle Fractures: Case Series
Status: COMPLETED
Conditions: Ankle Injuries|Ankle Fractures|Deltoid Ligament; Sprain (Strain) (Ankle)|Ligament Rupture
Interventions: PROCEDURE: Arthroscopic Deltoid Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Microwave Spherical Ablation and Traditional Microwave Ablation in Single Hepatocellular Carcinoma ≤5cm
Status: RECRUITING
Conditions: Hepatocellular Cancer|Microwave Ablation|Microwave Spherical Ablation|Prognosis
Interventions: DEVICE: True circular microwave needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Helicobacter Pylori Eradication Effect Before and After Training of Gastroenterologists
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: BEHAVIORAL: Standardized training on Helicobacter pylori eradication treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of the Liver in Glucose Homeostasis Using Metabolic Imaging
Status: COMPLETED
Conditions: Type 1 Diabetes|Bariatric Surgery Candidate
Interventions: DIAGNOSTIC_TEST: Multiparametric, multinuclear MR (DMI/ 13C-MRS/ GlycoCEST/GlycoNOE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS
Status: UNKNOWN
Conditions: PCOS
Interventions: DRUG: Dingkundan|DRUG: Dingkundan & Diane-35|DRUG: Diane-35
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
Status: COMPLETED
Conditions: Constipation Predominant Irritable Bowel Syndrome
Interventions: DRUG: Tenapanor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Perspective Midline Catheter in the Emergency Department
Status: WITHDRAWN
Conditions: Patient Satisfaction|Patient Preference
Interventions: PROCEDURE: Ultrasound Guided Vascular Access - Midline catheter|PROCEDURE: Ultrasound Guided Vascular Access - peripheral IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Familial Mediterranean Fever and Behçet: Analysis Before and After Covid19 Pandemic
Status: UNKNOWN
Conditions: Behcet Disease|COVID|FMF
Interventions: OTHER: ıt will be compared pain, sleep, fatigue, physical activity level and quality of life and questioning exercise habits before and after the covid-19 outbreak in patients with Behçet and FMF.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human HER2-targeted Macrophages Therapy for HER2-positive Advanced Gastric Cancer With Peritoneal Metastases
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: BIOLOGICAL: human HER2-targeted CAR-M cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Pharmacists' Interventions on the Quality of Life of HIV-TB Co-infection Outpatients in Indonesia
Status: COMPLETED
Conditions: Pharmaceutical Care|HIV/AIDS|Tuberculosis
Interventions: OTHER: Pharmaceutical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative Complication in Patients Undergoing Pancreatoduodenectomy
Status: UNKNOWN
Conditions: Periampullary Carcinoma|Pancreatic Fistula
Interventions: PROCEDURE: Omental Roll-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Carcinoma
Interventions: DRUG: Afatinib|BIOLOGICAL: Necitumumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Randomised Trial of RNActive® Cancer Vaccine in High Risk and Intermediate Risk Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Carcinoma
Interventions: BIOLOGICAL: CV9104|DEVICE: needle free injection device (Tropis®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prismatic Adaptation for Rehabilitation of Postural Imbalance After Stroke
Status: UNKNOWN
Conditions: Chronic Right Supratensorial Stroke Patients
Interventions: DEVICE: The prismatic adaptation (PA)|DEVICE: The sham prismatic adaptation (S-PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Assessment of CA 19-9 in Patients' With Thyroid Malignancies
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DIAGNOSTIC_TEST: Laboratory investigations for control: a-Complete blood count. b-Liver function test. c-kidney function test. d-thyroid-stimulating hormone,T3 and T4. e-Assessment of levels of CA19-9.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of Ascending Single and Multiple Doses of Nebulised SoftOx Inhalation Solution in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Safety
Interventions: DRUG: SoftOx Inhaled Solution (SIS)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-393 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: CKD-501 0.5mg Tab. 1T, D759 100mg Tab. 1T and D150 1000mg Tab. 1T|DRUG: CKD-393 0.5/100/1000mg formulation 1 Tab. 1T|DRUG: CKD-393 0.5/100/1000mg formulation 2 Tab. 1T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery With Implantable Biodegradable Carmustine (BCNU) Wafer Followed by Chemo for Patients With Recurrent Glioblastoma Multiforme
Status: WITHDRAWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: BCNU Wafer|DRUG: Irinotecan|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Acute Pancreatitis|Organ Failure, Multiple
Interventions: DEVICE: NucleoCapture device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Combination Cholesterol Treatments in Patients With High Cholesterol.
Status: COMPLETED
Conditions: Hyperlipidemia|Dyslipidemia
Interventions: DRUG: Minute Maid Heart Wise orange juice|DRUG: Welchol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Rejection|Antibody-mediated Rejection|Kidney Transplant Failure
Interventions: PROCEDURE: Kidney allograft biopsy depending on donor-derived cell-free DNA levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Masitinib in Relapse or Refractory Multiple Myeloma With t(4/14) Translocation Expressing or Not FGFR3
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: masitinib (AB1010)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Staging in Patients With Ovarian, Fallopian Tube, or Other Primary Abdominal Cancers
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Photopheresis and Low Dose Aldesleukin in Treating Patients With Steroid Refractory Chronic Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: BIOLOGICAL: Aldesleukin|PROCEDURE: Extracorporeal Photopheresis|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Myelodysplasia|Myelomonocytic
Interventions: DRUG: Lonafarnib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Rabbit Antithymocyte Globulin (rATG)/Rituximab in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair Implant
Status: UNKNOWN
Conditions: Migraine|Aura|Patent Foramen Ovale
Interventions: DEVICE: BioSTAR Septal Repair Implant System|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial on the Technical Aspects of Stoma Construction.
Status: COMPLETED
Conditions: Colostomy|Colorectal Neoplasm|Diverticulitis
Interventions: PROCEDURE: Cruciate incision|PROCEDURE: Circular incision|OTHER: Mesh enforced cruciate incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea and Arousal Threshold in Patients With Post-traumatic Stress Disorder
Status: WITHDRAWN
Conditions: Sleep Apnea, Obstructive; Post-Traumatic Stress Disorders
Interventions: DRUG: Trazodone|DRUG: Placebo|DEVICE: Epiglottic catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
Status: RECRUITING
Conditions: Stage IB Lung Non-Small Cell Carcinoma AJCC v7|Stage II Lung Non-Small Cell Cancer AJCC v7|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Carboplatin|DRUG: Cisplatin|OTHER: Clinical Observation|PROCEDURE: Computed Tomography|DRUG: Crizotinib|OTHER: Cytology Specimen Collection Procedure|PROCEDURE: Echocardiography|DRUG: Erlotinib|DRUG: Gemcitabine Hydrochloride|BIOLOGICAL: Nivolumab|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Pemetrexed Disodium|OTHER: Placebo Administration|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Combining Cognitive and Treadmill Training on Cognition and Walking Performance in Stroke With Cognitive Impairment
Status: COMPLETED
Conditions: Stroke|Cognitive Impairment
Interventions: OTHER: cognitive training combine treadmill training|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies
Status: COMPLETED
Conditions: Acute Lymphoid Leukemia|Acute Myeloid Leukemia|Anemia, Refractory, With Excess of Blasts|Solid Tumors
Interventions: DRUG: brentuximab vedotin|DRUG: brentuximab vedotin|DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Status: RECRUITING
Conditions: Post-mastectomy Pain Syndrome|Breast Cancer|Pain, Postoperative|Pain, Chronic
Interventions: DRUG: Lidocaine 20mg/ml|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Fluorescence Imaging|BIOLOGICAL: Panitumumab|DRUG: Panitumumab-IRDye800
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Immediate Effects of Physiotherapist and Self-administered Myofascial Release Techniques on Flexibility and Jumping Ability in Basketball Players
Status: NOT_YET_RECRUITING
Conditions: Myofascial Spasm
Interventions: OTHER: Self myofascial Release|OTHER: myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Status: COMPLETED
Conditions: Myeloproliferative Disorders|Acute Myelogenous Leukemia|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome|Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: T-cell replete PBPC allograft|DRUG: Methotrexate|DRUG: Cyclosporine|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BNT164a1|BIOLOGICAL: BNT164b1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Oxytocin Administered Orally Using a Medicated Lollipop on Peripheral Concentrations and Attention
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: oral lollipop with oxytocin (24IU)|DRUG: oral lollipop with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms
Status: RECRUITING
Conditions: Aortic Aneurysm
Interventions: BEHAVIORAL: Bahaviour at the time of an aortic aneurysm rupture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)
Status: RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Trimodulin|DRUG: Placebo (human albumin 1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics
Status: COMPLETED
Conditions: Diabetes|Hypertension|Hyperlipidemia|Constipation|Pain
Interventions: BEHAVIORAL: integration of pharmacist into primary care|DRUG: optimizing therapeutic treatments|BEHAVIORAL: optimizing processes of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Rural Alliance for Diabetes Prevention
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Zoom Group Video (GV)|BEHAVIORAL: Self Directed (SD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychosocial Adjunctive Treatment for Hypersomnia (PATH)
Status: COMPLETED
Conditions: Narcolepsy|Idiopathic Hypersomnia
Interventions: BEHAVIORAL: Cognitive-Behavior Therapy for Hypersomnia (CBT-H)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral Health Related Quality of Life Changes Between Clear Aligners and Vestibular Fixed Appliances
Status: COMPLETED
Conditions: Teeth Crowding
Interventions: DEVICE: Vestibular fixed appliances|DEVICE: Clear aligners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability and Pharmacokinetics of Single Dose of PF-06480605 in Japanese Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06480605|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of n-3 Polyunsaturated Fatty Acid Supplements in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Efamax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetic, Pharmacodynamic, Safety and Tolerability of ASKP1240 in de Novo Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: bleselumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used as a Bridging Stent With Branched and Fenestrated Endografts in the Treatment of Aortic Aneurysms Involving the Renal-Mesenteric Arteries
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Aortic Aneurysm|Thoracic Aortic Aneurysm
Interventions: DEVICE: GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhancement of Learning Associated Neural Plasticity by Selective Serotonin Reuptake Inhibitors
Status: UNKNOWN
Conditions: Ssri|Neuronal Plasticity
Interventions: DRUG: Escitalopram|DRUG: Placebo|OTHER: 3xMR scan (fMRI, DTI, strucutral MRI)|BEHAVIORAL: Association learning paradigm|BEHAVIORAL: Association re-learning paradigm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Add-on to Cognitive, Event-Related Potentials (ERP) and Electroencephalogram (EEG) Asymmetry in Affective Disorders
Status: WITHDRAWN
Conditions: Depressive Illness
Interventions: DRUG: bupropion|DRUG: citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Clinical Trial of Different Doses of the Immunotherapeutic Drug Mobilan (M-VM3) and Placebo in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Mobilan (M-VM3)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lower Limb Sensory Training on Functional Capacity in Hemiparetic Individuals
Status: UNKNOWN
Conditions: Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Interventions: OTHER: neurodevelopmental therapy|OTHER: Lower extremity sensory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Are Adductor Canal Blocks With Bupivacaine and Added Magnesium Better at Managing Post-operative Pain Than Bupivacaine and Added Buprenorphine in Patients Undergoing Same-day Discharge Total Knee Arthroplasty?
Status: UNKNOWN
Conditions: Post-operative Pain, Acute|Opioid Use
Interventions: DRUG: Adding Magnesium as an adjuvant to Bupivacaine in the adductor canal block (ACB) for same-day discharge total knee arthroplasty|DRUG: Adding Buprenorphine as an adjuvant to Bupivacaine in the adductor canal block (ACB) for same-day discharge total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment
Status: COMPLETED
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DEVICE: Nasal and Oronasal PAP Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria
Status: SUSPENDED
Conditions: Proteinuria|Hypertension|End Stage Renal Disease
Interventions: DRUG: losartan, hydrochlorothiazide|DRUG: hydrochlorothiazide, losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Virtual Tai Chi Easy for Registered Nurses
Status: RECRUITING
Conditions: Transition Shock|Nurses' Intention to Quit|Stress|Somatic Symptoms|Burnout|Trauma and Stressor Related Disorders
Interventions: BEHAVIORAL: Virtual Tai Chi Easy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Downhill-uphill Walking Exercises on Functional Level and Muscle Strength in Patients With Knee Arthroplasty.
Status: WITHDRAWN
Conditions: Knee Arthroplasty
Interventions: OTHER: Walking Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Nordic-Baltic Bifurcation Study IV
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Implantation of coronary stent in bifurcation lesion|PROCEDURE: Implantation of coronary stent in bifurcation lesion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lectranal® in Treatment of Seasonal Allergic Rhinitis Symptoms
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: Lectranal|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation
Status: COMPLETED
Conditions: Sick Sinus Syndrome
Interventions: DEVICE: Pacing leads to be implanted according randomization.|DEVICE: Selection 9000 prevent AF an Diagnose AF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Desarda Repair for Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Lichtenstein tension free reair|PROCEDURE: Desarda's repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Electrocautery Increase Postoperative Pain in Primary Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Different Teaching Strategies on the Academic Performance and Caring of Nursing Students
Status: COMPLETED
Conditions: Nursing Students|Older People
Interventions: OTHER: multimedia audio-visual program|OTHER: experiential learning programmes|OTHER: teachers' personal demonstration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Pancreatic Beta Cell Function|Glucotoxicity
Interventions: DRUG: intensive insulin group|DRUG: Oral AntiDiabetic Drug (glimepiride and metformin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke
Status: COMPLETED
Conditions: Stroke|Difficulty Walking
Interventions: BEHAVIORAL: Body weight supported treadmill training|BEHAVIORAL: Overground walking training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effectiveness of a Medical Device Based on Hyaluronic Acid in Wounds
Status: RECRUITING
Conditions: Wound Healing Disorder
Interventions: DEVICE: NOVA.EMOSTOP RE-EPITHELIZING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Microgynon|DRUG: Noristerat(BAY86-6308)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Chemoradiotherapy Using Gem Plus Nab-paclitaxel for Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Continuous Subcutaneous Pramlintide Infusion Therapy in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: IDDM
Interventions: DRUG: Continuous Pramlintide infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conscious Sedation for Transcatheter Aortic Valve Implantation
Status: RECRUITING
Conditions: Renal Function Disorder|Postoperative Delirium|Adverse Event|Death|Satisfaction
Interventions: DRUG: Continuous infusion of propofol|DRUG: Continuous infusion of dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation of "KeepWell" Using a Hybrid Effectiveness-Implementation Pragmatic Randomized Controlled Trial
Status: COMPLETED
Conditions: Chronic Disease
Interventions: OTHER: KeepWell tool|OTHER: Control - Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improvement of Pulmonary Insufficiency After Aortic Dissection With Sivelestat Sodium
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection|Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Interventions: DRUG: Sivelestat sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Platelet and Statin Therapy to Prevent Cancer-Associated Thrombosis
Status: COMPLETED
Conditions: Solid Tumor|Cancer
Interventions: DRUG: Aspirin|DRUG: Simvastatin|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Circulating Tumor DNA as a Theranostic Marker in the Management of Glioblastomas.
Status: TERMINATED
Conditions: Glioblastoma|Molecular Disease
Interventions: OTHER: Correlation between molecular anomalies of the primary tumor and circulating tumor DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Trial to Determine the Extent of Inter- and Intra-Treatment Organ Motion Using Active Breathing Control Device (ABC) in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: RADIATION: Standard Radiation Therapy|DEVICE: Active Breathing Control Device (ABC)|DEVICE: Computed Tomography Scan (CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Immunogenicity and Safety of Human Papillomavirus (HPV) Vaccine Co-administered With Another Vaccine in Healthy Female Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: HPV Vaccine (GSK580299) Cervarix TM|BIOLOGICAL: Engerix B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Airway Nerve Block Versus Nebulization by Lignocaine During Diagnostic Flexible Bronchoscopy Under Moderate Sedation.
Status: UNKNOWN
Conditions: Anesthesia
Interventions: OTHER: Group A|OTHER: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Bile Duct Injuries Following Open Cholecystectomy Versus Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystectomy|Common Bile Duct Diseases|Major Bile Duct Injury
Interventions: PROCEDURE: Surgical reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CPG10101 Combination Therapy For The Treatment Of Hepatitis C In Non-Responder (Null And Partial Responder) Hepatitis C Virus (HCV) Genotype 1 Infected Subjects
Status: COMPLETED
Conditions: Hepatitis, Chronic Active
Interventions: DRUG: CPG10101|DRUG: CPG10101|DRUG: Control|DRUG: CPG10101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Medicago Sativa on Oral Glucose Tolerance in Healthy Adults
Status: COMPLETED
Conditions: Glucose Tolerance
Interventions: DRUG: Medicago Sativa|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Paclitaxel for Patients With Advanced Biliary Tract Cancer Who Failed to Gemcitabine-based Treatment
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Lenvatinib Pill,Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of an Antibiotic Impregnated PICC Catheter Versus a Regular PICC Catheter in a Tertiary Care Setting
Status: WITHDRAWN
Conditions: Peripherally Inserted Central Catheters
Interventions: DEVICE: PICC (Cook, Bard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Orfadin Suspension Compared to Orfadin Capsules, and the Effect of Food on the Bioavailability of the Suspension
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nitisinone, capsule|DRUG: Nitisinone, suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RIFL (Rigid and Flexing Laryngoscope) vs. Fiberoptic Bronchoscope
Status: COMPLETED
Conditions: Intubation; Difficult
Interventions: DEVICE: RIFL (Rigid and Flexing Laryngoscope)|DEVICE: Fiberoptic Bronchoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective Trial of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Methicillin Resistant Staphylococcus Aureus Infections
Status: COMPLETED
Conditions: Methicillin Resistant Staphylococcus Aureus Skin Infections
Interventions: DRUG: nasal mupirocin|DRUG: topical 3% hexachlorophene body wash|DRUG: oral anti-MRSA antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia|Adults|Elderly
Interventions: DRUG: E2006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Understanding of Placebo Mechanisms Compensate for the Loss of Efficacy Associated With Open Label Placebo
Status: UNKNOWN
Conditions: Acute Pain
Interventions: OTHER: Educational movie on placebo mechanisms|OTHER: Informative movie on hand washing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Food Effect on the Pharmacokinetics of Nifurtimox Tablets in Chronic Chagas' Patients - Dietary Habits Study
Status: COMPLETED
Conditions: Chagas' Disease
Interventions: DRUG: Nifurtimox (Lampit, BAYA2502)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario
Status: NOT_YET_RECRUITING
Conditions: Survivorship|Cancer|Heart Diseases|Secondary Cancer|Colorectal Cancer|Breast Cancer
Interventions: BEHAVIORAL: ONLOOP program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies
Status: COMPLETED
Conditions: Bladder Cancer|Gastric Cancer|Non Small Cell Lung Cancer|NSCLC|Urothelial Carcinoma|Advanced Solid Tumor
Interventions: DRUG: APR-246 (eprenetapopt) + Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Swedish Birth Seat Trial
Status: COMPLETED
Conditions: Instrumental Vaginal Births|Oxytocin Augmentation for Labor|Maternal Blood Loss|Perineal Outcomes|Fetal Outcomes
Interventions: DEVICE: BirthRite birthing seat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Rotator Interval Injection Versus Intraarticular Hydrodilatation in Frozen Shoulder
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: DRUG: Triamcinolone (Shincort) injection to rotator interval|DRUG: Triamcinolone (Shincort) injection to posterior glenuhumeral recess
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality for Acute Pain and Anxiety During Egg Retrieval for in Vitro Fertility Treatment
Status: RECRUITING
Conditions: Infertility|In Vitro Fertilization|IVF|ART
Interventions: DEVICE: Oncomfort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Fenugreek Supplementation on Men's Health
Status: COMPLETED
Conditions: Aging|Testosterone Deficiency
Interventions: DIETARY_SUPPLEMENT: AlphaFen fenugreek 400 mg|DIETARY_SUPPLEMENT: AlphaFen fenugreek 500 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Conditioning Regimen for Myelodysplastic Syndrome With Moderate High IPSS-M Score
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of IgG Fc Glycan Composition in Human Immunity
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: IM Pneumococcal, meningococcal, or flu vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PERT to Improve Quality of Life in Patients Undergoing Pancreaticoduodenectomy: A Pilot Randomized Controlled Trial
Status: RECRUITING
Conditions: Pancreatic Insufficiency
Interventions: DRUG: PERT at discharge|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of Rimegepant for Migraine Prevention in Adults
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone and Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of LPRF Action in the Promotion of Wound Healing and Tissue Regeneration
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: leucocyte and platelet-rich fibrin (L-PRF) in combination with CAF|PROCEDURE: CAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PURI-PRO - Symptoms Impact and eHealth Intervention for Menopausal Women With Urinary Incontinence
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Experimental Group: eHealth intervention for UI symptoms improvement|BEHAVIORAL: Control Group: Delivery of a Health Literacy single-leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
Status: RECRUITING
Conditions: Hydrocephalus, Normal Pressure|Hydrocephalus
Interventions: DEVICE: eShunt Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric Patients
Status: RECRUITING
Conditions: Anxiety State|Perioperative/Postoperative Complications
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Left Atrial Volume Changes Who Underwent Cardioversion and Recurrence of AF After RF Ablation in Persistent AF (SAFE-AF)
Status: RECRUITING
Conditions: Persisent Atrial Fibrillation|Reversal of Atrial Enlargement|Recurrence of Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: 1. electrical/pharmacological cardioversion. 2.pulmonary vein isolation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism
Status: WITHDRAWN
Conditions: Pulmonary Embolism
Interventions: DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Co-administration With Omega-3 Fatty Acids on Obesity Parameters and Insulin Resistance
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Insulin Sensitivity|Type2 Diabetes|Visceral Obesity
Interventions: COMBINATION_PRODUCT: Symbiter-Omega|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Magnesium Pantoprazole|DRUG: Magnesium Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REThink Chronic-A Mobile Therapeutic Game
Status: ACTIVE_NOT_RECRUITING
Conditions: REThink Game|Treatment-as-usual
Interventions: DEVICE: REThink Therapeutic Game|DEVICE: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION