pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Decreases in Diffusing Lung Capacity for Carbon Monoxide (DLCO) in Occupational Divers and Their Impact on Decompression Sickness Risks
Status: COMPLETED
Conditions: Decompression Sickness
Interventions: OTHER: 20 meters air dive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery
Status: COMPLETED
Conditions: Skin Diseases|Nail Diseases|Nails, Ingrown
Interventions: DRUG: Polihexanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of a Blood Clotting Drug (Recombinant Factor XIII) Produced by Two Different Manufacturers in Healthy Male Subjects
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FXIII Deficiency|Healthy
Interventions: DRUG: catridecacog|DRUG: recombinant factor XIII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Albuferon With Ribavirin in Interferon Alfa Naive Subjects With Chronic Hepatitis C Genotype 2 or 3
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Albuferon|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ritonavir|DRUG: Saquinavir|DRUG: Methadone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superselective Citicoline and Verapamil for Ischemic Neuroprotection and Greater Effective Response
Status: WITHDRAWN
Conditions: Ischemic Stroke
Interventions: DRUG: Verapamil and Citicoline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Studies of New Model Haploidentical Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: CD19-chimeric Antigen Receptor T Cells|Relapsed and/or Refractory Acute Lymphoblastic Leukemia|the Haploidentical Hematopoietic Stem Cell Transplantation
Interventions: PROCEDURE: the new model of haplo-HSCT for r/r B-ALL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Nerve Block: Anatomical Insertion Point - A Prospective Randomised Double-Blind Controlled Trial
Status: UNKNOWN
Conditions: Femoral Nerve Disease
Interventions: PROCEDURE: Sartorius Muscle Twitch|PROCEDURE: Quadriceps Muscle Twitch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic Study of ACL Rupture With Anterior Drawer Test at 90° of Hip Flexion
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DIAGNOSTIC_TEST: anterior drawer test at 90° of hip flexion|DIAGNOSTIC_TEST: Lachman test|DIAGNOSTIC_TEST: anterior drawer test|DIAGNOSTIC_TEST: pivot-shift test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Richter Syndrome|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Durvalumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy, Exercise and Traction for Patients With Cervical Radiculopathy: A RCT
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: OTHER: Sham Traction|OTHER: Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Linking Facility-based Mortality Audits With Community Engagement in Gilgit-Baltistan, Pakistan
Status: TERMINATED
Conditions: External Causes of Morbidity and Mortality|Stillbirth|Neonatal Death
Interventions: OTHER: Audits only|OTHER: Audits with community feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Lurbinectedin|DRUG: Bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brown Fat Activation and Browning Efficiency Augmented by Chronic Cold and Nutraceuticals for Brown Adipose Tissue-mediated Effect Against Metabolic Syndrome (BEACON BEAMS Study)
Status: RECRUITING
Conditions: Energy Expenditure|Obesity|Brown Adipose Tissue
Interventions: OTHER: Cold Stimulation (CS)|OTHER: Browning Nutraceutical (BN)|OTHER: Cold Stimulation and Browning Nutraceutical (CSBN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aerobic Exercise and Transcranial Low Laser Therapy in Patients With Central Nervous System Injury
Status: UNKNOWN
Conditions: Post Stroke|Post-Traumatic Headache|Spinal Injuries|Cerebral Palsy, Spastic|Surgery|Sclerosis, Multiple|Spastic
Interventions: PROCEDURE: Transcranial Photobiomodulation|PROCEDURE: Transcranial Photobiomodulation (Placebo)|PROCEDURE: Cardiorespiratory Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mulligan Snag and Diaphragmatic Release on Thoracic Kyphosis
Status: COMPLETED
Conditions: Postural Kyphosis, Cervicothoracic Region
Interventions: OTHER: mulligan snag mobilization and diaphragmatic release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Changes in Metabolic Activity in Liver & Skeletal Muscle in Patients Suffering From Acromegaly
Status: UNKNOWN
Conditions: Acromegaly
Interventions: OTHER: 1H/31P Magnetic Resonance Spectroscopy|OTHER: oral glucose tolerance testing|OTHER: Thyroid sonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 4 Study Comparing IOP Lowering in OAG or OH in Caucasian or Japanese Subjects C-02-32
Status: TERMINATED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: IOP Lowering Medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM
Status: ENROLLING_BY_INVITATION
Conditions: Symptomatic Hypertrophic Cardiomyopathy (HCM)
Interventions: DRUG: Aficamten (5 - 20 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Compare 2 Different Formulations of BI 1358894 Tablets Taken With or Without Food
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1358894, intended Commercial Formulation (iCF) (T)|DRUG: BI 1358894, Trial Formulation 2 (TFII) (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Lumbar Spinal Manipulation, Physical Therapy and Surgical Management in the Treatment of Lumbar Spinal Stenosis
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis|Spinal Manipulation|Physical Therapy|Surgery
Interventions: DEVICE: lumbar traction|PROCEDURE: spinal manipulation|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Tetracaine HCl 3% and Oxymetazoline HCl 0.05%|DRUG: Placebo spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: B12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lorlatinib in ALK Inhibitor Treated Unresectable Advanced/Recurrent ALK-Positive Non Small Cell Lung Cancer Patients in India
Status: COMPLETED
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Versus Subacute Angioplasty in Patients With NON-ST-Elevation Myocardial Infarction
Status: TERMINATED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Group I: Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locally Delivered Antibiotics for the Treatment of Periodontitis
Status: UNKNOWN
Conditions: Periodontitis
Interventions: DRUG: Minocycline Topical|DRUG: Metronidazole Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Natural Fibre Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Diabetic Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
Status: TERMINATED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Anecortave Acetate Sterile Suspension (15 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Doses of STI571 in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparator Study Evaluating Patient Preference Of FFNS vs. FPNS
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: FPNS|DRUG: FFNS|DRUG: placebo FPNS|DRUG: placebo FFNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine Against Invasive Nontyphoidal Salmonella in Adults, Children, and Infants
Status: RECRUITING
Conditions: Salmonella Infections
Interventions: BIOLOGICAL: Measles and Rubella vaccine|BIOLOGICAL: Yellow Fever vaccine|BIOLOGICAL: Pentavalent vaccine|BIOLOGICAL: Pneumococcal vaccine|BIOLOGICAL: Inactivated polio vaccine|BIOLOGICAL: iNTS-GMMA Dose C|BIOLOGICAL: iNTS-GMMA Dose B|BIOLOGICAL: iNTS-GMMA Dose A|BIOLOGICAL: MenACWY|COMBINATION_PRODUCT: DTPa-HBV-IPV+Hib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect High Protein-Fiber Diet With Exercise on Acylated Ghrelin and Leptin in Obese Adolescents
Status: COMPLETED
Conditions: Weight Loss|Adolescent Obesity
Interventions: BEHAVIORAL: Modification Lifesyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Investigate Safety, Tolerability and MTD for SCO-101 in Combination With Gemcitabine and Nab-paclitaxel in Inoperable Pancreatic Cancer Patients.
Status: UNKNOWN
Conditions: Metastatic Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Adenocarcinoma|Inoperable Disease|Localized Pancreatic Adenocarcinoma
Interventions: DRUG: SCO-101|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esthetic Outcomes of Single Immediate Implant Placement
Status: COMPLETED
Conditions: Gingival Recession|Bone Loss, Alveolar
Interventions: PROCEDURE: Flapless immediate implant placement|PROCEDURE: Flap assisted immediate implant placement|DEVICE: Implant and temporary crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer（MAPS）
Status: UNKNOWN
Conditions: Salivary Gland Neoplasms
Interventions: DRUG: Pyrotinib|DRUG: Bicalutamide|DRUG: Leuprorelin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: tumor-specific TCR-T cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Demonstrate the Efficacy of a Dietary Supplement in Decreasing Cardiovascular Risk
Status: COMPLETED
Conditions: Low-Moderate Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Red Rice Yeast|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial to Investigate Cafusertib Hydrochloride in Combination With Low Dose Cytarabine in Chinese Patients With Acute Myeloid Leukaemia (AML)
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cafusertib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Pantoprazole on the Pharmacokinetics of Fradafiban After Multiple Oral Doses of Lefradafiban Over 5 Days in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lefradafiban tablet|DRUG: Lefradafiban double chamber sachet|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-flow Extracorporeal Carbon Dioxide Removal in COVID-19-associated Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: ARDS|Hypercapnic Respiratory Failure|AKI
Interventions: DEVICE: ECCO2R
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation Paired With FES Cycling Post SCI
Status: RECRUITING
Conditions: Incomplete Spinal Cord Injury
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: functional electrical stimulation (FES) cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: enzalutamide|DRUG: bicalutamide|PROCEDURE: orchiectomy|DRUG: leuprolide acetate|DRUG: goserelin acetate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 and BL-B01D1 in Combination With Osimertinib Mesylate Tablets in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: BL-B01D1|DRUG: Osimertinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Orelabrutinib in Combination With Gemox in Refractory / Relapsed Diffuse Large B-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: DLBCL
Interventions: DRUG: Orelabrutinib and Gemox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DEVICE: Fentanyl IONSYS|DEVICE: Morphine IV PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant MEDI 4736 +/- Tremelimumab in Locally Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug Co-Administered With Insulin in Patients With Type 2 Diabetes (0478-065)
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK0478 (muraglitazar)|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Training Program to Improve Balance and Prevent Falls in Older Adults
Status: COMPLETED
Conditions: Accidental Falls|Musculoskeletal Equilibrium
Interventions: PROCEDURE: computerized visual training|PROCEDURE: computerized word puzzles|PROCEDURE: video-game based visual training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Agents
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: PROCEDURE: Implantation of two iStent inject micro-bypass stents|DRUG: Topical travoprost|DEVICE: Two iStent inject micro-bypass stents|DRUG: Tobramycin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Neoadjuvant and Adjuvant Control by Precision Medicine in Rectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Total neoadjuvant therapy (TNT)|DIAGNOSTIC_TEST: Minimal residual disease (MRD)|RADIATION: Long radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and Exercise Versus Exercise Only for Chronic Patellofemoral Pain Syndrome
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome|Tibial Tubercle Transfer|Home Exercise Program
Interventions: PROCEDURE: Tibial Tubercle Transfer|PROCEDURE: Home Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability, and PK of Multiple Ascending Doses of GC021109 in Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: GC021109|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of HER2-Positive Metastatic Breast Cancer With Herceptin and Bevacizumab (Antibodies Against HER2 and VEGF)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumab (drug), Herceptin (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VR-Enhanced Psychoeducation for Chronic Pain: A Primary Care Pilot Study
Status: RECRUITING
Conditions: Chronic Pain|Central Sensitization
Interventions: BEHAVIORAL: VR-Enhanced Psychoeducational Program for Chronic Pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stereotactic Body Radiation Therapy in Liver Cancer That Cannot be Removed by Surgery or Transplant
Status: WITHDRAWN
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: RADIATION: stereotactic body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores
Status: UNKNOWN
Conditions: Anastomotic Leak
Interventions: DIAGNOSTIC_TEST: Predictors of intestinal anastomosis leakage, application of new predictors and new scores
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Renal AL Amyloid Involvement and NEOD001
Status: TERMINATED
Conditions: Amyloidosis
Interventions: DRUG: NEOD001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation.
Status: UNKNOWN
Conditions: Atrial Fibrillation, Paroxysmal
Interventions: DRUG: Saline 0.9%|DRUG: Canrenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Botulinum Toxin Type A for the Treatment of Non-neurogenic Urinary Urge Incontinence
Status: COMPLETED
Conditions: Urinary Urge Incontinence
Interventions: DRUG: Botulinum Toxins, Type A|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2090314 and Chemotherapy in Participants With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: LY2090314|DRUG: FOLFOX|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Rasburicase (Fasturtec®) in the Prevention and Treatment of Hyperuricemia in Pediatric Patients With Non-Hodgkin's Lymphoma and Acute Leukemia
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: RASBURICASE SR29142
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plaque Regression and Progenitor Cell Mobilization With Intensive Lipid Elimination Regimen (PREMIER), Phase I
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: intensive LDL-lowering therapy|DRUG: standard statin monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AONDA Therapeutic Indication Study I
Status: COMPLETED
Conditions: Bullous Keratopathy|Corneal Erosion|Entropion|Corneal Edema|Corneal Dystrophy|Corneal Ulcer|Foreign Body in Cornea|Bell Palsy|Keratoconjunctivitis|Filamentary Keratitis|Sicca Syndrome; Keratoconjunctivitis (Etiology)
Interventions: DEVICE: Lotrafilcon A contact lenses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Antiviral Activity, Safety, and Pharmacokinetics of Repeated Doses of Orally Administered JNJ 53718678 Against Respiratory Syncytial Virus Infection.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: Placebo|DRUG: JNJ-53718678
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping Aminosalicylate Therapy in Inactive Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease|Remission
Interventions: OTHER: 5-ASA Withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: POMx In the Treatment of Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: One POMx capsule daily|DRUG: 2 POMx Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Rotator Cuff Repair With Multimodal Analgesia(MMA)
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Arthroscopic rotator cuff repair with intraoperative periarticular injection|PROCEDURE: Arthroscopic rotator cuff repair with non-injection of MMA drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT
Status: COMPLETED
Conditions: Hyperparathyroidism; Secondary, Renal
Interventions: DRUG: Cinacalcet HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of ABBV-744 in Participants With Relapsed/Refractory Acute Myeloid Leukemia (AML) Cancer
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: ABBV-744
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Neuroprotective Capacity of Scp776 in Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke (AIS)
Interventions: DRUG: Placebo|DRUG: scp776 (1.9 mg/kg)|DRUG: scp776 (3.8 mg/kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Sensor-controlled Digital Game for Hypertension Self-care in a Native American Community
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Sensor-controlled digital game|BEHAVIORAL: Sensor only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE
Status: RECRUITING
Conditions: NAFLD|NASH - Nonalcoholic Steatohepatitis
Interventions: DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)|DIAGNOSTIC_TEST: Magnetic resonance elastography (MRE)|DEVICE: Prototype MRE soft flexible passive transducer paddle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Revacept in Symptomatic Carotid Stenosis
Status: COMPLETED
Conditions: Carotid Stenosis|Atherosclerosis|Stroke|Transient-ischaemic Attack|TIA|Amaurosis Fugax
Interventions: DRUG: Revacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Iontophoresis vs. Ultrasound and Iontophoresis in Plantar Fasciitis". Plantar Fasciitis"
Status: COMPLETED
Conditions: Iontophoresis|Ultrasound Therapy; Complications|Fasciitis, Plantar|Pain, Acute
Interventions: DRUG: Application of lidocaine together with dexamethasone|DEVICE: Application of ultrasound as physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Switch From Oral Iron to Intravenous Ferric Carboxymaltose in Non-dialysis Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Iron Deficiency|Anaemia
Interventions: DRUG: intravenous ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conservative Treatment of Patients With Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: DEVICE: Chiropractic w/Activator & Self Care|DEVICE: Dental Care & Self Care|OTHER: Sham AMCT|OTHER: Self-Care Only Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anti-platelet Therapy in the Prevention of Cardiovascular Disease in Patients With COPD (APPLE-COPD: ICON 2)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Ticagrelor|DRUG: Aspirin|DRUG: Placebo Aspirin|DRUG: Placebo Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Oral OZ439 Prototype Formulations Administered With Piperaquine Phosphate (PQP)
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: 800mg OZ439 prototype formulation 1|DRUG: 800mg OZ439 prototype formulation 2|DRUG: 800mg OZ439 prototype formulation 3|DRUG: 960mg PQP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multi Vitamin and Mineral Supplementation of Liver Enzymes and Sonography in Patient With NAFLD
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: COMBINATION_PRODUCT: Multiviamins and minerals|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab With Laser Interstitial Therapy for Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|GBM
Interventions: DRUG: Avelumab|COMBINATION_PRODUCT: MRI-guided LITT therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4SC-201 (Resminostat) in Advanced Colorectal Carcinoma
Status: COMPLETED
Conditions: Advanced Colorectal Carcinoma
Interventions: DRUG: 4SC-201(Resminostat)|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry Platform Gastric/Esophageal Cancer (SAPHIR)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: OTHER: Routine care as per site standard
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE
Status: SUSPENDED
Conditions: Cancer|Depression|Fatigue|Pain|Sleep
Interventions: BEHAVIORAL: Stepped collaborative care intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
Status: UNKNOWN
Conditions: B-cell Acute Lymphoblastic Leukemia|Lymphoma|Myeloid Leukemia|Multiple Myeloma|Hepatoma|Gastric Cancer|Pancreatic Cancer|Mesothelioma|Colorectal Cancer|Esophagus Cancer|Lung Cancer|Glioma|Melanoma|Synovial Sarcoma|Ovarian Cancer|Renal Carcinoma
Interventions: BIOLOGICAL: CAR-T cell immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tarceva (Erlotinib) in Patients With Advanced Non-Small Cell Lung Cancer Naive to Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Neurological Effects of Adding Maraviroc to HAART Regimen in Patients With HIV (HANDmac)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)|HIV Associated Neurocognitive Disorders (HAND)
Interventions: DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Maternal Odor and Kangaroo Care on Serum Cortisol and Comfort Levels in Preterm Infants: a Randomised Trial
Status: COMPLETED
Conditions: Preterm Birth Complication|Stress Related Disorder|Cortisol Overproduction
Interventions: BEHAVIORAL: Exposure to maternal odor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Fermented Red Clover on Muscle Strength and Muscle Mass
Status: COMPLETED
Conditions: Estrogen Deficiency
Interventions: DIETARY_SUPPLEMENT: Red clover|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Cytokine-induced Killer Cell (CIK) Treatment in Patients After Resection of Liver Cancer
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: cytokine-induced killer cell (CIK) treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Black Seed Oil in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Black Seed Oil|DRUG: Anti-Diabetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Oral Cancer|VEGFR2 Inhibitor|Programmed Cell Death 1 Inhibitor|Inductive Therapy
Interventions: DRUG: Camrelizumab|DRUG: Apatinib|PROCEDURE: Radical surgery|RADIATION: Post-operative radiotherapy/chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment
Status: UNKNOWN
Conditions: Rectal Carcinoma
Interventions: RADIATION: IMRT-SIB|DRUG: Capecitabine|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of S-Amlodipine Gentisate Compared to Amlodipine Besylate to Treat Mild-to-Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: S-amlodipine gentisate|DRUG: Amlodipine besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Levosimendan on Microcirculation in Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Levosimendan|DRUG: dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Repetitive Transcranial Magnetic Stimulation (rTMS) in Bulimia
Status: UNKNOWN
Conditions: Bulimia Nervosa
Interventions: PROCEDURE: Repetitive transcranial Magnetic Stimulation (rTMS)|PROCEDURE: Repetitive transcranial Magnetic Stimulation SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Isotretinoin Plus Interferon in Treating Patients With Recurrent Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Esophageal Cancer|Head and Neck Cancer|Lung Cancer|Non-melanomatous Skin Cancer|Penile Cancer
Interventions: BIOLOGICAL: recombinant interferon alfa|DRUG: isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses
Status: RECRUITING
Conditions: End Stage Renal Disease
Interventions: DRUG: Adipose Derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyzing Composition and Lubrication Properties of Synovial Fluid
Status: COMPLETED
Conditions: Knee Osteoarthritis|HA Injection|One Injection Per Week for Five Week|Synovial Fluid Composition|Synovial Fluid Lubrication
Interventions: OTHER: Synovial fluid composition and lubrication analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SMS Mobile Technology to Improve Early Childhood Vaccine Coverage in Guatemala
Status: COMPLETED
Conditions: Adherence to Vaccination Schedules|Timeliness of Vaccination|Acceptability of SMS Reminder Program
Interventions: BEHAVIORAL: SMS message|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC
Status: TERMINATED
Conditions: Lung Neoplasms, Non-Small Cell Lung Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Uveitis|Arthritis, Juvenile Rheumatoid
Interventions: DRUG: TNFR:Fc
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparing the Reciprocal Inhibition Method and Post-isometric Inhibition Method of Muscle Energy Technique on the Spinal Reflex Excitability in Healthy Subjects
Status: UNKNOWN
Conditions: Relaxation; Joint|Limitation, Mobility|Relaxation; Lumbosacral
Interventions: OTHER: Reciprocal Inhibition Muscle Energy Technique|OTHER: Post-Isometric Inhibition Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: Ombitasvir/paritaprevir/ritonavir|DRUG: Dasabuvir|DRUG: Ribavirin|DRUG: Ombitasvir mini tablet|DRUG: Paritaprevir mini tablet|DRUG: Ritonavir mini tablet|DRUG: Dasabuvir mini tablet|DRUG: Ribavirin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles
Status: COMPLETED
Conditions: OHSS (Ovarian Hyperstimulation)
Interventions: DRUG: Buserelin and Pregnyl|DRUG: Pregnyl|DRUG: Buserelin and Pregnyl|DRUG: Pregnyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety & Efficacy Study With Deep Transcranial Magnetic Stimulation for the Treatment of Post-Traumatic Stress Disorder (PTSD)
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorder
Interventions: DEVICE: Deep TMS System|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: pegnivacogin/anivamersen|DRUG: Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Followed by Chemoradiation Versus Chemoradiation for Stage IIIC Cervical Cancer Patients: A Randomized Phase III Trial
Status: RECRUITING
Conditions: Cervical Cancer|Neoadjuvant Chemotherapy|Bulky Neoplasm
Interventions: DRUG: Albumin-Bound Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TYK2 Inhibition in Paradoxical Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Symptomatic Asthma In Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/ fluticasone propionate Diskus® inhaler 50/100 mcg|DRUG: fluticasone propionate 2 x 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy of Alendronate With and Without Calcium or Calcium Alone In the Treatment of Osteoporosis in Postmenopausal Women (0217-088)(COMPLETED)
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: MK0217, alendronate sodium / Duration of Treatment : 2 Years|DRUG: Comparator : calcium carbonate /Duration of Treatment : 2 Years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Confortable Environment, Kangaroo Care and Music Therapy in Newborns in Neonatal Intensive Care Unit
Status: RECRUITING
Conditions: Premature Infant Disease|Newborn Morbidity
Interventions: OTHER: in the field of rehabilitation and neonatal care: the combination of Kangaroo care method and music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chinese Medicine WT for Spinocerebellar Ataxia Type 3
Status: COMPLETED
Conditions: Ataxia, Spinocerebellar|Insulin-Like Growth Factor I|Medicine, Chinese Traditional
Interventions: DRUG: Chinese medicine WT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effectiveness of Contour Augmentation in Sites With Early Implant Placement
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially|Dental Implants, Single-tooth|Grafting Bone
Interventions: PROCEDURE: Contour augmentation with implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Prucalopride in Participants With Chronic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Post Approval Clinical Study of ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain
Status: COMPLETED
Conditions: Bone Metastasis
Interventions: DEVICE: ExAblate MRgFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE