pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Safety and Efficacy Study of ChAdOx1 LS2 and MVA LS2
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: ChAdOx1 LS2|BIOLOGICAL: MVA LS2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of RSLV-132 in Subjects With Long COVID
Status: COMPLETED
Conditions: Post-acute Corona Virus 19 (COVID-19) (Long COVID)
Interventions: DRUG: RSLV-132|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Johrei Therapy and CBT-I in Facilitating Sleep in ICU Survivors
Status: UNKNOWN
Conditions: Sleep Disturbances in Survivors of Critical Illness
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I)|OTHER: Johrei therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Therapy for Poor Prognosis Immunoglobulin A Nephropathy
Status: COMPLETED
Conditions: Glomerulonephritis, IGA|Nephropathy, IGA|IGA Nephropathy
Interventions: DRUG: ACE inhibitor + statin|DRUG: Sirolimus (study drug)+ACE inhibitor + statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Change in Microbiome Diversity and Urine Metabolites After Lignite Extract Use
Status: UNKNOWN
Conditions: Microbiome
Interventions: DIETARY_SUPPLEMENT: Lignite Extract|OTHER: Herbal tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Engaging Fathers for Effective Child Nutrition and Development in Tanzania
Status: COMPLETED
Conditions: Child Nutrition and Early Child Development
Interventions: BEHAVIORAL: Nutrition, mothers|BEHAVIORAL: Nutrition, mothers and fathers|BEHAVIORAL: Nutrition+parenting, mothers|BEHAVIORAL: Nutrition+parenting, mothers and fathers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: GVAX Pancreas Vaccine|RADIATION: Stereotactic Body Radiation|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laser Acupuncture on Adhesive Small Bowel Obstruction
Status: UNKNOWN
Conditions: Adhesive Small Bowel Obstruction
Interventions: PROCEDURE: Laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPG and RANKL Plasma Level After Administration of Unfractionated Heparin (UFH) and Low-Molecular-Weight Heparin (LMWH) in Hemodialysis
Status: UNKNOWN
Conditions: Renal Failure|Hemodialysis
Interventions: DRUG: law molecular weigth heparin|DRUG: unfractioned heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors
Status: RECRUITING
Conditions: Refractory Cancer|Recurrent Cancer|Solid Tumor, Adult|Cancer
Interventions: BIOLOGICAL: IMA402 (Phase Ia)|BIOLOGICAL: IMA402 (Phase Ib)|BIOLOGICAL: IMA402 (Phase II)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthristis
Interventions: PROCEDURE: Conventional Physical Therapy for Knee Osteoarthriths|PROCEDURE: Virtual Reality-Based Therapeutic Exercise regimes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Super-Bolus: Effects on Postprandial Glycemia After High Glycemic Index Meal
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin Glulisine|DRUG: Insulin Aspart|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Reported Outcomes in Renal Transplant Patients Tolerating Gastrointestinal (GI) Symptoms Converted to Myfortic (EC-MPS)
Status: UNKNOWN
Conditions: Kidney Transplant
Interventions: DRUG: Myfortic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression & Other Neuropsychiatric Symptoms After Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: TBI Depression
Interventions: COMBINATION_PRODUCT: Low Frequency Right sided repetitive transcranial magnetic stimulation (LFR rTMS)|DEVICE: Sham Comparator: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: Resveratrol (3, 4´, 5 trihydroxystilbene)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Double Blind, Placebo Controlled Trial With AMG 108 in Patients With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Diabetes Mellitus
Interventions: BIOLOGICAL: AMG 108|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Steroid Treatment After Posterior Lamellar Corneal Transplantation
Status: WITHDRAWN
Conditions: Endothelial Dystrophy|Secondary Bullous Keratopathy|Posterior Lamellar Keratoplasty|Descemet's Stripping Endothelial Keratoplasty
Interventions: DRUG: Weak steroid (Flurolon, Allergan)|DRUG: Potent steroid (Maxidex, Alcon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of PPD Through Self-portraits
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: DIAGNOSTIC_TEST: draw a person (DAP)|DIAGNOSTIC_TEST: Edinburgh Postnatal Depression Scale (EPDS)|DIAGNOSTIC_TEST: Beck Depression Inventory- II (BDI-II)|DIAGNOSTIC_TEST: Traumatic Events Questionnaire (TEQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rectal Cancer And Pre-operative Induction Therapy Followed by Dedicated Operation. The RAPIDO Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer
Interventions: OTHER: M1 scheme|OTHER: standard long course chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lateral Epicondylitis Extracorporeal Shock Wave Therapy, Ultrasound Iontophoresis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Extracorporeal shock wave group|OTHER: ultrasound group|OTHER: dexamethasone iontophoresis group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Method and Timing to Provide Information on Epidural and Spinal Anaesthesia for Primiparas
Status: UNKNOWN
Conditions: Patient Satisfaction|Confidence, Self
Interventions: OTHER: Educational video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of AL-794 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses, and the Antiviral Activity of Multiple Doses in an Influenza Challenge Study
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: AL-794|OTHER: Placebo/Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Intranasal Ketamine for Social Impairment in Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropathic Investigation and Anticholinergic Treatment of Bladder Dysfunction in Diabetes and Stroke Patients
Status: WITHDRAWN
Conditions: Urinary Incontinence|Bladder Dysfunction
Interventions: DRUG: Fesoterodine Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Benigh Prosatic Hyperplasia/Lower Urinary Tract Symptoms
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DEVICE: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Metabolism of 14 Carbon [14C]-GSK3640254
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254 Oral tablet|DRUG: [14C]-GSK3640254 intravenous infusion|DRUG: [14C]-GSK3640254 powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fragility Assessment in Adults With ADHD and Mental Retardation
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Mental Retardation
Interventions: OTHER: ADS severity|OTHER: Adaptative and intellectual functioning|OTHER: Psychiatric and somatic comorbidities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Blood Flow Restriction (Bfr) Exercise on Acute Systemic Myokine Levels in Healthy Trained Men
Status: NOT_YET_RECRUITING
Conditions: Muscle Hypotrophy
Interventions: OTHER: BFR-RE|OTHER: HL-RE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Innovative Ultrasound Technology in Neuromuscular Disease
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Muscular Dystrophy|Radiculopathy|Myopathy|Polyneuropathy and Mononeuropathies|Trauma Injury|Orthopedic Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Kinetic Oscillation Stimulation by the Chordate System S101 in the Treatment of Non Allergic Rhinitis
Status: COMPLETED
Conditions: Nasal Congestion|Non-allergic Rhinitis
Interventions: DEVICE: Chordate S101|DEVICE: Chordate S101 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Valacyclovir Suppression to Improve the Stability of Vaginal Flora Among HSV-2 Seropositive Women
Status: WITHDRAWN
Conditions: Bacterial Vaginosis|Herpes Simplex Virus Type II
Interventions: DRUG: Placebo|DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiological Evaluation of Radiesse Implantation in the Hands
Status: COMPLETED
Conditions: Volume Loss in the Dorsum of the Hand
Interventions: DEVICE: Radiesse injectable implant and 2% lidocaine HCL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation In-patient With Neurological Sequelae Due to Encephalitis or Meningitis
Status: COMPLETED
Conditions: Encephalitis|Meningitis
Interventions: COMBINATION_PRODUCT: Stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hyaluronic Acid Injection and Exercise Treatments in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Intra-articular hyaluronic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buccal Misoprostol Versus IV Oxytocin in Prevention of Postpartum Hemorrhage
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Misoprostol|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Occlusal Splints or Botulinum Toxin?
Status: COMPLETED
Conditions: Myofascial Pain|Temporomandibular Disorder
Interventions: DEVICE: Occlusal Splint|DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Safety and Tolerability of SHR-1901 in Subjects With Advanced Malignant Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Tumors
Interventions: DRUG: SHR-1901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Three Different Doses of OPC-34712 in the Treatment of Adults With Acute Schizophrenia
Status: COMPLETED
Conditions: Acute Schizophrenia
Interventions: DRUG: OPC-34712 [Brexpiprazole] High Dose|DRUG: Experimental: OPC-34712 [Brexpiprazole] Middle Dose|DRUG: Experimental: OPC-34712 [Brexpiprazole] Low Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RISE With Residents
Status: ACTIVE_NOT_RECRUITING
Conditions: Domestic Violence|Child Maltreatment|Pediatric ALL|Psychiatry|Education, Medical, Graduate
Interventions: OTHER: Violence, Evidence, Guidance, Action Project (VEGA) Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: glioblastoma multiforme multipeptide vaccine IMA950|BIOLOGICAL: sargramostim|DRUG: temozolomide|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia (CAH)
Interventions: DRUG: Fludrocortisone|DRUG: Hydrocortisone|DRUG: Letrozole|DRUG: Flutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exosome as the Prognostic and Predictive Biomarker in EBC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer|HER2-positive Breast Cancer
Interventions: PROCEDURE: exosome and ctDNA evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Chemotherapy Followed by Peripheral Stem Cell or Bone Marrow Transplant Compared With Chemotherapy Alone in Treating Patients With Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: epirubicin hydrochloride|DRUG: etoposide|DRUG: etoposide phosphate|DRUG: ifosfamide|DRUG: paclitaxel|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: milk supplement|DIETARY_SUPPLEMENT: soy milk supplement|BEHAVIORAL: resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Valproate in Dementia (VALID)
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Valproate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436|DRUG: GSK2118436|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation.
Status: COMPLETED
Conditions: Alpha 1 Antitrypsin Deficiency
Interventions: DRUG: Alpha-1 Antitrypsin (human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atazanavir Twice Daily
Status: COMPLETED
Conditions: HIV Infections|Protease Inhibitor
Interventions: DRUG: Atazanavir Sulphate|DRUG: Atazanavir Sulphate|DRUG: Atazanavir Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of Nicotine Acid on Dyslipidaemia in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Dyslipidaemia
Interventions: DRUG: nicotine acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Suture Materials With Different Absorption Times on Isthmocele: Prospective Randomized Study
Status: COMPLETED
Conditions: Suture, Complication|Istmocel
Interventions: PROCEDURE: Suture materials effect on istmocel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: CS1-CAR T Therapy|DRUG: Cyclophosphamide|DRUG: Fludarabine|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is NMES Treatment in Sepsis/ Septic Shock Patients Protective in Development of ICU-AW?
Status: COMPLETED
Conditions: Intensive Care Unit Acquired Weakness|Sepsis, Severe
Interventions: DEVICE: NMES GROUP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Parents|Stress
Interventions: BEHAVIORAL: Parent-implemented Early Start Denver Model|BEHAVIORAL: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Importance of Albumin Infusion Rate for Plasma Volume Expansion Following Major Abdominal Surgery
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Urogenital Neoplasm|Systemic Inflammatory Response Syndrome|Hypovolemia
Interventions: DRUG: 5% Albumin infusion 30 min|DRUG: 5% Albumin infusion 3 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Maintain Radial Artery Patency Following Diagnostic Coronary Angiography - Diagnostic Transradial Coronary Angiography Without Systemic Anticoagulatio
Status: UNKNOWN
Conditions: Patients Undergoing Diagnostic Coronary Angiography
Interventions: OTHER: Traditional punkcture site and No anticoagulation|OTHER: Traditional punkcture site and ACT-guided anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Epoetin Alfa in Treating Fatigue in Patients With Advanced Solid Tumors Who Are Not Receiving Chemotherapy
Status: WITHDRAWN
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: Epoetin alfa|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reinnervation of Facial Muscles After Lengthening Temporalis Myoplasty
Status: TERMINATED
Conditions: Facial Paresis
Interventions: DRUG: injection of 1% lidocaine, 2mL for facial nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibiotic "Dysbiosis" in Preterm Infants
Status: COMPLETED
Conditions: Enterocolitis, Necrotizing|Bacteremia|Bronchopulmonary Dysplasia|Intraventricular Hemorrhage|Periventricular Leukomalacia|Chronic Lung Disease|Ileal Perforation
Interventions: DRUG: Antibiotic|OTHER: Gastric fluid|OTHER: Breast milk|OTHER: Stool samples|DRUG: Antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Low Protein Content Formula in the First Months of Life: a RCT
Status: COMPLETED
Conditions: Safety Issues|Infant Nutrition Disorders
Interventions: DIETARY_SUPPLEMENT: Low protein formula|DIETARY_SUPPLEMENT: Standard protein formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acupuncture for Preterm Infants Requiring Eye-exam
Status: COMPLETED
Conditions: Retinopathy of Prematurity|Pain|Acupuncture|Premature Infant
Interventions: DEVICE: Magnetic acupuncture|DEVICE: stickers (magnets removed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amantadine for Treatment of Symptoms of the Post-traumatic Confusional State
Status: COMPLETED
Conditions: Traumatic Brain Injury|Posttraumatic Confusional State|Delirium
Interventions: DRUG: Amantadine hydrochloride|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Program of Integrated Care for Patients With Chronic Obstructive Pulmonary Disease and Multiple Comorbidities
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Multiple Comorbidity
Interventions: BEHAVIORAL: 40 minute standardized education session|BEHAVIORAL: Individualized action plan|BEHAVIORAL: Individualized care plan|BEHAVIORAL: Standardized reinforcement/motivational interviewing and action plan teach-back sessions|BEHAVIORAL: Tele-home monitoring|BEHAVIORAL: Coordinated and improved communication|BEHAVIORAL: Priority access|BEHAVIORAL: Dictated patient summary|BEHAVIORAL: in-hospital rehabilitation/self-management program|BEHAVIORAL: Smoking cessation|BEHAVIORAL: Action plan Respirologist|BEHAVIORAL: Web based self management materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Resveratrol to Enhance Vitality and Vigor in Elders
Status: COMPLETED
Conditions: Mitochondrial Function|Physical Function
Interventions: DRUG: Resveratrol 1000 mg/day|DRUG: Resveratrol 1500 mg/day|OTHER: Vegetable cellulose|OTHER: All groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: aldesleukin|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy of FOLFOX + Panitumumab Followed by FOLFIRI + Bevacizumab (Sequence 1) Versus FOLFOX + Bevacizumab Followed by FOLFIRI + Panitumumab (Sequence 2) in Untreated Patients With Wild-type RAS Metastatic, Primary Left-sided, Unresectable Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: Panitumumab|DRUG: Bevacizumab|DRUG: FOLFIRI regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of an Inactivated EV71 Vaccine in Infants
Status: COMPLETED
Conditions: Infection, Viral, Enterovirus
Interventions: BIOLOGICAL: 100U EV71 vaccine with adjuvant|BIOLOGICAL: 200 U EV71 vaccine with adjuvant|BIOLOGICAL: 400U EV71 vaccine with adjuvant|BIOLOGICAL: 200U EV71 vaccine without adjuvant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: AMBULATE: Cardiva Mid-Bore VVCS vs. Manual Compression for Multiple Femoral Venous Access Sites, 6 - 12F ID
Status: COMPLETED
Conditions: Surgical Wound
Interventions: DEVICE: Cardiva Mid-Bore VVCS|OTHER: Manual compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Couple Therapy for Perinatal Distress
Status: NOT_YET_RECRUITING
Conditions: Perinatal Depression|Perinatal Anxiety
Interventions: DRUG: Psychopharmacological Intervention|BEHAVIORAL: Cognitive Behavioral Couple Therapy|OTHER: Combination of Psychopharmacological Intervention and CBCT|OTHER: Placebo and No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Ultrasound-guided Femoral Vein Accessibility, Safety and Time for Atrial Fibrillation Treatment
Status: COMPLETED
Conditions: Atrial Fibrillation|Peripheral Vascular Disease|Vascular Access Complications
Interventions: DEVICE: Real-time ultrasound-guided puncture|OTHER: Anatomical landmark guided puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TPF+CCRT vs.CCRT+PF in High Risk Nasopharyngeal Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: TPF+CCRT|DRUG: CCRT+ PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Prophylactic Versus On-Demand Treatment With Feiba NF in Subjects With Hemophilia A or B and a High Titer Inhibitor
Status: COMPLETED
Conditions: Hemophilia A or B With Inhibitors|Hemophilia A|Hemophilia B
Interventions: BIOLOGICAL: Factor VIII Inhibitor Bypassing Activity (nanofiltered, vapor heat-treated)|BIOLOGICAL: Factor VIII Inhibitor Bypassing Activity (nanofiltered, vapor heat-treated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Rifampin on the Pharmacokinetics of PCI-32765 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PCI-32765|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Enoxaparin in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: enoxaparin|DRUG: chemotherapy with LMWH - enoxaparin|DRUG: only chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Diagnostics in Cervical Dysplasia
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: Estrogen|DIAGNOSTIC_TEST: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Astragalus-based Formula: Qingshu-Yiqi-Tang on Modulating Immune Alterations in Lung Cancer Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Astagalus-based Formula: Qingshu-Yiqi-Tang
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Endocrine Therapy Versus Chemotherapy in Premenopausal Patients With ER+ & HER2- Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Goserelin+TAM+AI|DRUG: Epirubicin+CTX+5-Fu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-Acetylcysteine and L-carnitine in Pcos
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: N-Acetylcysteine|DRUG: L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intrapulmonary Percussive Ventilation in Preterm Infants
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: DEVICE: Intrapulmonary Percussive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and PK Characteristics of the Co-administration of JLP-2002 and Comparator in Healthy Volunteers
Status: COMPLETED
Conditions: Overactive Bladder(OAB)
Interventions: DRUG: JLP-2002|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: management of therapy complications|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo
Status: UNKNOWN
Conditions: Patients With Active Non-segmental Vitiligo.|Evaluation of the Efficacy of UVB and Fluticason Proprionate 0.05%|Cream Compared to NB-UVB Alone in Patients With Non-segmental Vitiligo
Interventions: DRUG: Fluticasone proprionate 0.05% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: DRUG: 5-aminolévulinique acid (5-ALA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Nicorandil on Neointima
Status: UNKNOWN
Conditions: Angina, Unstable|Diabetes Mellitus
Interventions: DRUG: Nicorandil|DRUG: nicorandil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study Investigating the Effects of Early Skin Barrier Protection on the Development of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: emollient (Cetaphil cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Physical Exercise in Patients With Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Physical Activity|Telomere Shortening|Premature Aging
Interventions: OTHER: Strength physical exercise programme|OTHER: Normal life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Efficacy of Azithromycin and Levamisole Versus of Azithromycin in in the Treatment of Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Levamisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Obesity|Liver Diseases|Liver Fibrosis|Liver Fat|Metabolic Dysfunction-Associated Steatotic Liver Disease|Metabolic Dysfunction-Associated Steatohepatitis|MASLD|MASH|Weight Loss|Insulin Resistance|Insulin Sensitivity|Insulin Sensitivity/Resistance|Metabolic Disease|Diabetes|Diabetes Mellitus, Type 2|NASH With Fibrosis|Non-Alcoholic Fatty Liver Disease|Non Alcoholic Fatty Liver|Non-alcoholic Steatohepatitis
Interventions: DEVICE: ESG + lifestyle modification|BEHAVIORAL: Lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OsrhAAT or Placebo in Healthy Volunteers
Status: UNKNOWN
Conditions: Emphysema Secondary to Congenital AATD
Interventions: DRUG: OsrhAAT 1 mg/kg IV|DRUG: OsrhAAT 3 mg/kg IV|DRUG: OsrhAAT 10 mg/kg IV|DRUG: OsrhAAT 20 mg/kg IV|DRUG: OsrhAAT 40 mg/kg IV|DRUG: OsrhAAT 60 mg/kg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pharmacodynamic Study of Cilostazol in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cilostazol|DRUG: Acetylsalicylic acid|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Unilateral Retinoblastoma
Interventions: COMBINATION_PRODUCT: Combination Chemotherapy plus Intrathecal Topotecan|COMBINATION_PRODUCT: Higher Dose Combination Chemotherapy plus Intrathecal Topotecan|COMBINATION_PRODUCT: Higher Dose Combination Chemotherapy plus Intrathecal Topotecan and Orbital Radiotherapy|OTHER: No Adjuvant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: COMBINATION_PRODUCT: TVB-009|COMBINATION_PRODUCT: Prolia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Congenital Heart Disease in Children|Neuroprotection
Interventions: DRUG: Allopurinol|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hormones and Reduction in Co-users of Marijuana and Nicotine
Status: COMPLETED
Conditions: Marijuana Dependence
Interventions: DRUG: Progesterone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Effects of Testosterone Replacement Therapy in Hypogonadal Type 2 Diabetic Patients" (SETH2)
Status: COMPLETED
Conditions: Hypogonadism, Male|Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: Testosterone Undecanoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis|Knee Pain Chronic
Interventions: DIETARY_SUPPLEMENT: Experimental: Curcumin derivate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients
Status: NOT_YET_RECRUITING
Conditions: Renal Failure|Chronic Kidney Diseases
Interventions: DEVICE: PD cycler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Oxaliplatin in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumoperitoneum and Cerebral Oxygenation
Status: COMPLETED
Conditions: Laparoscopic Nephrectomy|Cerebral Oxygen Saturation
Interventions: PROCEDURE: Standart pressure pneumoperitoneum|PROCEDURE: Low pressure pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bronchial Artery Infusion of Gemcitabine in Treating Patients With Recurrent or Progressive Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Micro-randomized Trial of HeartSteps, an mHealth Intervention for Increasing Physical Activity
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: HeartSteps: A just-in-time adaptive intervention for increasing physical activity amongst sedentary adults.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Sintilimab Plus Anlotinib Combined With Chemotherapy as Neoadjuvant Therapy in TNBC
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Sintilimab|DRUG: Anlotinib|DRUG: Nab paclitaxel|DRUG: Carboplatin|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Intravenous Oxytocin for Analgesia to Heat Pain
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: Low dose oxytocin|DRUG: High dose oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Safety and Effectiveness of 2 Doses of Levofloxacin Given for Different Time Periods in Patients With Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety of Low and Very Low Carbohydrate Diets in Young Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Diet Modification|Child, Only
Interventions: OTHER: Low carbohydrate diet|OTHER: Very low carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin for Intra-arterial Chemotherapy in Pediatric Retinoblastoma.
Status: RECRUITING
Conditions: Retinoblastoma
Interventions: DRUG: Nitroglycerin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Non-acute Coronary occlusIon Treated By Everolimus ELuting Stent
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Occlusion|Percutaneous Coronary Intervention
Interventions: DEVICE: Implantation of sirolimus-eluting coronary stent|DEVICE: Implantation of everolimus-eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Prevention of Postoperative Nausea and Vomiting
Status: UNKNOWN
Conditions: PONV
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Psychological Well-being of Trainee Civil Servants in Pakistan
Status: COMPLETED
Conditions: Psychological Distress|Coping Skills|Well-being|Psychological Capital|Anxiety
Interventions: BEHAVIORAL: Psycho-social skills development workshops based on PM plus|BEHAVIORAL: Routine training induction sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of LV5FU2 Versus FOLFOX for Curatively-resected, Node-positive Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Curatively-resected, Node-positive Esophageal Squamous Cell Carcinoma
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Oral Mirabegron With Different Release Rates Versus Intravenous (IV) Mirabegron
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Mirabegron
Interventions: DRUG: mirabegron|DRUG: mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Palliative Radiation Combined With Pembrolizumab in Unresectable Metastatic Stage IV Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: COMBINATION_PRODUCT: Palliative Radiation and Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Yield of Cap Assisted Upper Endoscopy in Esophagus
Status: COMPLETED
Conditions: Endoscopic Diagnosis in Esophagus
Interventions: PROCEDURE: cap assisted upper endoscopy|PROCEDURE: standard upper endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study of a Natural Remedy for Rheumatoid Arthritis vs. Commonly Used Conventional Medications
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: A Natural Remedy for Rheumatoid Arthritis vs. Common Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Two Different Doses of Asacol in the Treatment of Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Asacol 800 mg (mesalamine)|DRUG: Asacol 400 mg (mesalamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cognitive Training on Academic Task Performance in Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD|Attention
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Cognitive training-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT