pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Assess the Immunogenicity and Safety of CSL's 2013/2014 Formulation of Enzira® Vaccine in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Enzira® vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PTSD Treatment For Suicidal and Multi-Diagnostic Clients
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder|Suicide|Self-injurious Behavior
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Dialectical Behavior Therapy Prolonged Exposure protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Training of Graduate Students in General Psychotherapeutic Skills (TRIPS)
Status: RECRUITING
Conditions: Deliberate Practice Training of Psychotherapeutic Skills|Theoretical Teaching of Psychotherapeutic Skills
Interventions: OTHER: Deliberate practice training|OTHER: Theoretical teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Minimally Invasive Distal Chevron in Comparison to the Reverdin-Isham Osteotomy for Hallux Valgus Correction
Status: COMPLETED
Conditions: Hallux Valgus and Bunion
Interventions: PROCEDURE: distal minimally invasive chevron osteotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
Status: COMPLETED
Conditions: Lumbar Pain Syndrome
Interventions: PROCEDURE: high intensity physiotherapy|PROCEDURE: moderate intensity physiotherapy|PROCEDURE: low intensity physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors
Status: RECRUITING
Conditions: Central Nervous System Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Cognitive Assessment|PROCEDURE: Magnetic Resonance Imaging|DRUG: Memantine Hydrochloride|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations
Status: TERMINATED
Conditions: Solid Tumours
Interventions: DRUG: Debio1347 (CH5183284)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy and Safety of 2 Doses of Org 34517 as Adjunctive Therapy in Subjects With Psychotic Major Depression (28130)(P05845)
Status: COMPLETED
Conditions: Depression|Depressive Disorders|Psychotic Disorders
Interventions: DRUG: Org 34517|DRUG: Org 34517|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Use of Negative Pressure Wound Therapy THR TKR RCT
Status: RECRUITING
Conditions: Knee Arthropathy|Hip Arthropathy|Negative Pressure Wound Therapy
Interventions: DEVICE: negative pressure wound therapy|OTHER: standard dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sevoflurane and Desflurane on Treg
Status: COMPLETED
Conditions: Transplant; Failure, Kidney
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)
Status: RECRUITING
Conditions: Locally Advanced Esophageal Squamous Cell Carcinoma
Interventions: DRUG: S-1|DRUG: Toripalimab|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants
Status: RECRUITING
Conditions: Tuberculosis
Interventions: DRUG: GSK2556286|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled, Multi-center, Phase III Clinical Study to Investigate Recombinant Humanized PD-1 Monoclonal Antibody Injection (JS001) Versus Dacarbazine as the 1st-line Therapy for Unresectable or Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma|Unresectable Melanoma
Interventions: BIOLOGICAL: JS001 240mg Q2W|DRUG: Dacarbazine 1000mg/m2 Q3W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study
Status: COMPLETED
Conditions: Plaque|Gingivitis|Gum Inflammation|Bleeding
Interventions: OTHER: Listerine Zero Mouthwash (without alcohol)|OTHER: Listerine Antiseptic Mouthwash (with alcohol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: TTS-fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Non-Hodgkin-Lymphoma by Combination of Lenalidomide + Rituximab, Dexa, High-dose ARA-C and CisP
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)|Follicular Lymphoma Grade III (FL III°)|Mantle Cell Lymphoma (MCL), Blastoid Variant|Burkitt Lymphoma (BL)|Aggressive Marginal Zone Lymphoma (MZL)
Interventions: DRUG: Rituximab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Dexamethasone|DRUG: Cytarabine|DRUG: Lenalidomide|DRUG: PegFilgrastim|PROCEDURE: peripheral stem cell collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced and/or Recurrent Head and Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bakery Products for Non-Coeliac Gluten Sensitive Consumers
Status: UNKNOWN
Conditions: Non Coeliac Gluten Sensitivity
Interventions: OTHER: Normal gluten containing bread|OTHER: Bread with reduced gliadins content|OTHER: Bread with reduced ATIs content|OTHER: Bread with reduced overall protein content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study on the Effect of Combined Estrogen and Progestogen Therapy on Endometrial Repair After Induced Abortion
Status: RECRUITING
Conditions: Pregnancy Complications
Interventions: DRUG: 17β-estradiol/dydrogesterone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Crisaborole Ointment 2% in Mild to Moderate Atopic Dermatitis
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Crisaborole 2% Top Oint
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Algorithm to determine overdose from opioid abuse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study About no Antimicrobial Prophylaxis in Totally Laparoscopic Distal Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer|Complication of Surgical Procedure
Interventions: PROCEDURE: No use of antimicrobial prophylaxis|PROCEDURE: Use of antimicrobial prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manuka Honey Sinus Rinse Study
Status: COMPLETED
Conditions: Cystic Fibrosis|Infection, Bacterial
Interventions: DEVICE: Manuka honey sinus rinse|DEVICE: Standard sinus rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanding Patient Applicability With Polymer Sealing Ovation Alto Stent Graft Investigational Device Exemption (IDE) Study
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: Ovation Alto Abdominal Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education With or Without Exercise and Counseling in Preventing Lymphedema in Women With Stage I, Stage II, or Stage III Breast Cancer Who Are Undergoing Axillary Lymph Node Dissection
Status: COMPLETED
Conditions: Lymphedema
Interventions: OTHER: quality of life assessment|OTHER: educational intervention|PROCEDURE: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Bioavailability of a Single 12 mg Dose of Perampanel for Three Intravenous Infusion Durations Relative to a Single 12 mg Perampanel Oral Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Perampanel|DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of Aerodigestive Stimulation Therapy Trial
Status: NOT_YET_RECRUITING
Conditions: Feeding Disorder Neonatal
Interventions: PROCEDURE: Esophageal stimulation with high resolution esophageal manometry and nutritive oral feeding therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: gB/MF59 Vaccine in Preventing Cytomegalovirus Infection in Healthy Adolescent Females
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: MF-59|DRUG: Placebo|BIOLOGICAL: CMV gB vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Pioglitazone and Ramipril Combination Therapy in Treating Non-diabetic Hypertensive Patients.
Status: COMPLETED
Conditions: Inflammation|Hypertension
Interventions: DRUG: Pioglitazone|DRUG: Pioglitazone and ramipril|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Schizoaffective Disorder|Healthy
Interventions: DRUG: Memantine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Activ-L™ Artificial Disc Treatment of Degenerative Disc Disease in the Treatment of Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: Activ-L Artificial Disc|DEVICE: ProDisc-L Total Disc Replacement or Charité Artificial Disc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paracervical Block in First Trimester Surgical Abortions
Status: COMPLETED
Conditions: Pain|Surgical Abortion
Interventions: DRUG: lidocaine|DRUG: ketorolac and lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Longstanding Unexplained Health Complaints
Status: COMPLETED
Conditions: Somatization Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|PROCEDURE: Recommendation of care (letter to general practitioner [GP])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors|Minimal Residual Disease
Interventions: DIAGNOSTIC_TEST: liquid biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: I-CARE 2: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms in Hispanic Individuals
Status: RECRUITING
Conditions: Caregiver Burden|Alzheimer Disease
Interventions: BEHAVIORAL: Brain CareNotes|BEHAVIORAL: Dementia Guide Expert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Bovine Colostrum Supplementation in Older Adults
Status: COMPLETED
Conditions: Sarcopenia|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Bovine colostrum|DIETARY_SUPPLEMENT: Whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of BIBR 277 in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Low dose of BIBR 277|DRUG: Medium dose of BIBR 277|DRUG: High dose of BIBR 277
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ATL-962 in Obese Diabetics
Status: COMPLETED
Conditions: Non-Insulin-Dependent Diabetes Mellitus|Obesity
Interventions: DRUG: ATL-962|DRUG: Orlistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of an Ectoine-containing Cream in the Treatment of Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: DEVICE: Atopiclair|DEVICE: EHK02-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AROPE : Early Ovarian Reserve Decreased : Impact of Exposure to Persistent Endocrine Disruptors and Organic Solvents
Status: COMPLETED
Conditions: Female Infertility
Interventions: OTHER: Self-administered questionnaire and blood and urine samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Carfilzomib|DRUG: Daratumumab SC|DRUG: Lenalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Status and Pregnancy or Delivery Complications in Type 1 Diabetes Mellitus Pregnant Women
Status: COMPLETED
Conditions: Periodontal Diseases|Periodontitis|Pregnancy Complications|Pregnancy in Diabetic|Diabetes Mellitus, Type 1|Delivery Complication
Interventions: OTHER: Pregnancy and/or delivery complications|OTHER: Periodontal disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aumolertinib in EGFR-Mutant Resected Stage IB-IIIA NSCLC (AERESA).
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Aumolertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro-ultrasound for Prostate Cancer Diagnosis
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Prostate biopsy systematic random prostate biopsy (TRUS-Bx) + eventual MRI-targeted biopsy (MRI-TBx) + eventual microUS-targeted (Micro-US-TBx)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Developing Accessible Telehealth Programs for Diabetes and Hypertension Management in Bolivia
Status: COMPLETED
Conditions: Hypertension|Diabetes
Interventions: OTHER: HITCM-only|OTHER: HITCM+CP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hyaluronic Acid for Soft Tissue Injuries
Status: UNKNOWN
Conditions: Elbow Tendinopathy|Ankle Sprains
Interventions: DEVICE: Soft Tissue Adapted Biocompatible Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esophageal and Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux
Status: COMPLETED
Conditions: Larynx Disease|Gastroesophageal Reflux
Interventions: PROCEDURE: Esophageal and Laryngeal biopsies|PROCEDURE: egd with biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Evaluation of Adverse Reactions in Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Exenatide|DRUG: Linagliptin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management in ED for Incision and Drainage of Abscess
Status: WITHDRAWN
Conditions: Abscess
Interventions: DRUG: Fentanyl|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neutron Radiation Therapy and Pembrolizumab in Treating Participants With Advanced Urothelial Carcinoma
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mecamylamine for the Treatment of Patients With Depression and Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence|Depression
Interventions: DRUG: Mecamylamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Zirconium silicate (acute phase)|DRUG: Zirconium silicate (subacute phase)|DRUG: Placebo (acute phase)|DRUG: Placebo ( subacute phase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Physical Therapy on Breast Cancer Related Lymphedema
Status: COMPLETED
Conditions: Lymphoedema|Breast Cancer
Interventions: PROCEDURE: Physical TherapyA|PROCEDURE: Physical TherapyB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: KGX101- Cohort -1|DRUG: KGX101- Cohort 1|DRUG: KGX101- Cohort 2|DRUG: KGX101- Cohort 3|DRUG: KGX101- Cohort 4|DRUG: KGX101- Cohort 5|DRUG: KGX101 and Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2.4 mm Variable Angle LCP Two-Column Volar Distal Radius
Status: COMPLETED
Conditions: Distal Radius Fractures
Interventions: DEVICE: Variable Angle Distal Radius Plate ® (Surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tushirikiane HIV-self Testing Intervention With Urban Refugee Youth in Kampala, Uganda
Status: COMPLETED
Conditions: HIV/AIDS|HIV Infections|Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: m-Health|DIAGNOSTIC_TEST: HIV self-testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Macrolide Azithromycin to Prevent Rapid Worsening of Symptoms Associated With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Macrolide Antibiotic (Azithromycin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rehabilitation With Personalized Strategies According to Muscle Volume Before Knee Arthroplasty
Status: UNKNOWN
Conditions: Gonarthrosis|Arthroplasty
Interventions: OTHER: Personalized rehabilitation program with electrostimulation|OTHER: Global rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: UVA1 Light for Scleroderma and Similar Conditions
Status: TERMINATED
Conditions: Keloid|Scleroderma|Scars|Granuloma Annulare|Acne Keloidalis Nuchae
Interventions: DEVICE: German manufactured UVA1 emitting light system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on TIL for the Treatment of Advanced Hepatobiliary-Pancreatic Cancers
Status: RECRUITING
Conditions: Advanced Liver Cancers|Tumor Infiltrating Lymphocyte|Treatment Side Effects|Effects of Immunotherapy|Advanced Pancreatic Cancers
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocyte
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Trastuzumab Deruxtecan|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pembrolizumab|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Ad5-yCD/mutTKSR39rep-hIL12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urogenital Prolapse|Vaginal Vault Prolapse|Cystocele|Uterine Prolapse|Vaginal Prolapse|Pelvic Floor Disorders
Interventions: DRUG: Conjugated Estrogens Cream|DRUG: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Matched Paired Pharmacodynamics and Feasibility Study of Durvalumab in Combination With Chemotherapy in Frontline Ovarian Cancer (N-Dur)
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Fallopian Tube Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: DRUG: Carboplatin|BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe
Status: UNKNOWN
Conditions: Endothelial Function
Interventions: DRUG: simvastatin, combined with simvastatin ezetimibe, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Specifically Developed Exercise Intervention on Falls Among Older Adults in Nursing Homes
Status: ACTIVE_NOT_RECRUITING
Conditions: Fall|Exercise Intervention|Elderly Population
Interventions: OTHER: Physical exercise interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Melatonin Agonist on Hospitalized Patients With Confirmed or Suspected COVID-19
Status: UNKNOWN
Conditions: Covid19|Lung Injury
Interventions: DRUG: Ramelteon 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Low Level Light Therapy for Prevention of Oropharyngeal Mucositis in Pediatric Transplants Patients
Status: COMPLETED
Conditions: Oropharyngeal Mucositis|Myeloablative Hematopoietic Cell Transplantation|Low Level Light Therapy
Interventions: DEVICE: Low Level Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Hypertonic Saline Therapy in Ambulatory Heart Failure Unit.
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Hypertonic saline solution plus intravenous furosemide|DRUG: Intravenous furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Education and Humor-Based Practices on Breastfeeding
Status: COMPLETED
Conditions: Humor as Topic|Breast Feeding|Mother-Child Relations|Breastfeeding, Exclusive
Interventions: BEHAVIORAL: breastfeeding - humor training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate of the Absorption, Metabolism, and Excretion of 14C-JNJ-39823277 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 14C-JNJ-39823277
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.
Status: RECRUITING
Conditions: Severe Aplastic Anemia|Acquired Amegakaryocytic Thrombocytopenia|Acquired Pure Red Cell Aplasia|Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Rituximab|DRUG: Rabbit ATG|DRUG: Cyclophosphamide|DRUG: Fludarabine|RADIATION: Total Body Irradiation|BIOLOGICAL: Cell Infusion|DRUG: Post-Transplant G-CSF|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: leucovorin calcium|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of AB-836 in Healthy Subjects and Subjects With Chronic HBV Infection
Status: TERMINATED
Conditions: Chronic Hepatitis
Interventions: DRUG: AB-836|DRUG: Placebo|DRUG: AB-836|DRUG: Placebo|DRUG: Nucleos(t)ide Analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia Effects of Nalbuphine vs Sulfentanil
Status: UNKNOWN
Conditions: C.Delivery; Surgery (Previous), Gynecological
Interventions: DRUG: Nalbuphine|DRUG: Sufentanil|DRUG: flurbiprofen axetil|DRUG: ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta
Status: TERMINATED
Conditions: Osteogenesis Imperfecta
Interventions: BIOLOGICAL: Setrusumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Move to Music Video Intervention for ICU Survivors
Status: COMPLETED
Conditions: Critical Illness|Intensive Care Unit Syndrome
Interventions: BEHAVIORAL: Move to Music Intervention (M2M)|BEHAVIORAL: Move to Music -Video (M2M-V) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Flat-knitted Compression Stockings Class I and II on Venous Malformations
Status: COMPLETED
Conditions: Vascular Malformations|Vascular Malformation Peripheral|Venous Malformation|Vascular Diseases
Interventions: DEVICE: compression stockings class I|DEVICE: compression stockings class II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study of AK1320 Encapsulated Microspheres (AK1320 MS)
Status: TERMINATED
Conditions: Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: DRUG: AK1320 MS|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Intervention for Toddlers With Autism (EARLY STEPS)
Status: COMPLETED
Conditions: Autism|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Early Start Denver Model|BEHAVIORAL: Standard community care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Motor Intervention to Increase Health Related Physical Fitness in Children With Congenital Heart Disease
Status: COMPLETED
Conditions: Congenital Heart Disease|Health Related Physical Fitness|Motor Skills|Cardiovascular Prevention
Interventions: BEHAVIORAL: Supervised web- and home-based exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients
Status: NOT_YET_RECRUITING
Conditions: Oxycodone|Analgesia|Mechanical Ventilation|Postoperative|Remifentanil
Interventions: DRUG: Oxycodone Hydrochloride|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Juanbi Pill for Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Juanbi Pill|Rheumatoid Arthritis
Interventions: DRUG: Juanbi pill|DRUG: Juanbi pill placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Session Percutaneous Mechanical Thrombectomy for the Treatment of Ilio-femoral Deep Vein Thrombosis: A Preliminary Evaluation
Status: TERMINATED
Conditions: Deep Vein Thrombosis|Venous Thromboembolism
Interventions: DEVICE: Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pico-Salax Versus Poly-Ethylene Glycol for Bowel Cleanout Before Colonoscopy in Children
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: PEG-Lyte®|DRUG: Pico-Salax®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Feasibility of Home Delivery of Colon Capsule Endoscopy Service With the Help of 5 G Technology
Status: RECRUITING
Conditions: Colorectal Cancer|Colon Capsule Endoscopy
Interventions: OTHER: Setting up home delivery of Colon capsule endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Parallel Oxygen Delivery Through a Tracheal Gas Insufflation (TGI) and a T-piece, on Blood Gases and Respiratory Rate, in ICU Tracheostomized Patients
Status: COMPLETED
Conditions: Resp Gas Exchange Disorder Nos
Interventions: DEVICE: Tracheal gas insufflation 6 L/min|DEVICE: Tracheal gas insufflation 11 L/min|DEVICE: Tracheal gas insufflation catheter, without gas flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)
Status: COMPLETED
Conditions: Breast Cancer|Colorectal Cancer|Non-Small Cell Lung Cancer|Glioblastoma|Renal Cell Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Emactuzumab and RO7009789 Administered in Combination in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Emactuzumab|DRUG: RO7009789
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Selected Advanced Solid Tumors
Interventions: BIOLOGICAL: MEDI5752|DRUG: Pemetrexed|DRUG: Carboplatin|BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel or Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ¡Si, Yo Puedo Control Mi Diabetes!: A Diabetes Self-management Education Program for Hispanic/Latinos
Status: COMPLETED
Conditions: Type 2 Diabetes, Hispanic/Latinos, Diabetes Self-management Education
Interventions: BEHAVIORAL: diabetes self-management education
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuation of Antiarrhythmics Following Ventricular Tachycardia Catheter Ablation
Status: TERMINATED
Conditions: Tachycardia, Ventricular|Catheter Ablation
Interventions: DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenal Venous Sampling in Patients With Overt or Subclinical Cushings Syndrome, and Bilateral Adrenal Tumors
Status: UNKNOWN
Conditions: Cushing Syndrome
Interventions: RADIATION: Adrenal venous sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colorectal Cancer RECHALLENGE
Status: WITHDRAWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: OXALIPLATIN (SR96669)|DRUG: 5-FLUOROURACIL (5-FU)|DRUG: LEUCOVORIN (LV)|DRUG: BEVACIZUMAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis (RMS)
Interventions: BIOLOGICAL: Ublituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Evaluation of the Work Rehabilitation Effort "Best iLag"
Status: COMPLETED
Conditions: Musculoskeletal Pain|Work Related Illnesses|Burnout, Professional
Interventions: BEHAVIORAL: Group-based activity|BEHAVIORAL: Individual activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Thoracis Plane Block Versus Parasternal Intercostal Nerve Plane Block for Cardiac Surgery
Status: RECRUITING
Conditions: Cardiac Surgery
Interventions: DRUG: transversus thoracis muscle plane block (TTP)|DRUG: parasternal intercostal nerve block (PSI block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy Adherence of APAP Therapy Initiation in Sleep-lab Versus at Home
Status: UNKNOWN
Conditions: Patient Compliance
Interventions: PROCEDURE: Automatic Positive Airway Pressure (APAP) initiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan 70 mg/m2|DRUG: Irinotecan 240 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Intensity Modulated Radiation Therapy With Cisplatin to Treat Stage I-IVA Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: RADIATION: Intensity Modulated Radiation Therapy (IMRT)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of corticoïd Infiltration Via Sacro-coccygien Hiatus in Discal Sciatica
Status: TERMINATED
Conditions: Discal Sciatica
Interventions: DRUG: Prednisolone acetate|DRUG: sham procedure|DRUG: comparator : physiological solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive Chemotherapy
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DEVICE: Health Telemonitoring|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Transparent Cap-assisted SpyGlass for Biliary Stricture
Status: UNKNOWN
Conditions: Bile Duct Stricture|Endoscopic Retrograde Cholangiopancreatography|Biliary Disease|Biliary Tract Neoplasms
Interventions: DEVICE: Transparent cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A 12-Week, Placebo Controlled Trial of Ziprasidone as Monotherapy for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Ziprasidone|DRUG: Ziprasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: TAP block|PROCEDURE: TAP block|DRUG: liposomal bupivacaine plus free bupivacaine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Atorvastatin on Psoriasis Severity and Endothelial Function
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.
Status: COMPLETED
Conditions: Migraine With Aura
Interventions: OTHER: Magnetic resonance imaging|OTHER: Transcranial Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors in Children
Interventions: DRUG: Combined administration of irinotecan and rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention With Phytochemicals and Polyunsaturated Fatty Acids in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Prostate cancer, phytochemical and PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
Status: COMPLETED
Conditions: Postpartum Sepsis|Postpartum Endometritis|Postpartum Fever
Interventions: DRUG: Azithromycin|DRUG: Azithromycin and amoxicillin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of LYC-55716 With Pembrolizumab in Adult Subjects With Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: LYC-55716|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Becaplermin Gel for MARTORELL's Hypertensive Leg Ulcers
Status: COMPLETED
Conditions: MARTORELL'S ULCER|Hypertensive Leg Ulcer|Necrotic Angiodermatitis
Interventions: DRUG: becaplermin gel|DRUG: Duoderm Hydrogel™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms
Interventions: DRUG: Ulixertinib|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological Diseases
Status: COMPLETED
Conditions: Graft Versus Host Disease|Hematopoietic/Lymphoid Cancer
Interventions: DRUG: fludarabine phosphate|DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DRUG: tacrolimus|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT