pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Role of Vitamin D in Chronic Urticaria and Angioedema Treatment
Status: COMPLETED
Conditions: Urticaria|Angioedema|Hives|Swelling
Interventions: DRUG: High Dose Vitamin D3|DRUG: Low Dose Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)
Status: COMPLETED
Conditions: Fatigue Syndrome, Chronic|Myalgic Encephalomyelitis
Interventions: DIETARY_SUPPLEMENT: melatonin plus zinc|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Amount of Nintedanib and Pirfenidone in the Blood When Nintedanib and Pirfenidone Are Given Separately or in Combination
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: nintedanib|DRUG: pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibrotactile Coordinated Reset for the Treatment of Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Chronic Stroke
Interventions: DEVICE: Active Vibrotactile coordinated reset|DEVICE: Sham vibrotactile coordinated reset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids in Treating Patients With Advanced Cancer Who Have Significant Weight Loss
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: R-DA-EDOCH Versus R-CEOP90, With/Without Upfront Auto-HSCT in Young Patients With High-risk DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: R-DA-EPOCH|DRUG: R-CEOP90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Dialectical Behavioral Therapy (d-DBT) Skills for Acute Suicidality in Psychiatric Inpatients
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: OTHER: digital DBT skills intervention|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UCN-01 and Carboplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: 7-hydroxystaurosporine|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Therapeutic Strategies in First-line in Patients With Epithelial Advanced Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer, Epithelial
Interventions: DRUG: CC0 - Carboplatin (IV) - Paclitaxel (IV)|DRUG: CC0 - Cisplatin (IP) - Epirubicin (IV)|DRUG: CC>0 - Carboplatin (IV)- Paclitaxel (IV)|DRUG: CC>0 - Cisplatin (IP/IV)- Epirubicin (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plinabulin vs. Pegfilgrastim in Prevention of TAC Induced Neutropenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Neutropenia
Interventions: DRUG: Pegfilgrastim|DRUG: Plinabulin|OTHER: D5W Placebo|DRUG: Docetaxel, doxorubicin, and cyclophosphamide (TAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chronic Lung Allograft Dysfunction MRI Study
Status: NOT_YET_RECRUITING
Conditions: Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Interventions: DIAGNOSTIC_TEST: Spirometry|DIAGNOSTIC_TEST: Contrast Lung Computed Tomography (CT) Scan|DIAGNOSTIC_TEST: Oxygen enhanced magnetic resonance imaging (OE-MRI) Scan|DIAGNOSTIC_TEST: 129Xe MRI scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Post Marketing Study to Evaluate the Efficacy and Safety of Solifenacin in Patients With OAB (Overactive Bladder) After TURP (Trans-urethral Resection of Prostate) or PVP (Photoselective Vaporization of Prostate)
Status: COMPLETED
Conditions: Overactive Bladder|Benign Prostate Hyperplasia|Transurethral Resection of Prostate|Photoselective Vaporization Prostatectomy
Interventions: DRUG: Solifenacin Succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pantoprazole Prophylaxis Against Delayed CINV for Patients Receiving Breast Cancer Chemotherapy
Status: COMPLETED
Conditions: Oncology|Breast Cancer|Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Pantoprazole 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Chemotherapy-induced Thrombocytopenia
Interventions: BIOLOGICAL: Romiplostim|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Efficacy And Security Of Ibandronate For Osteoporosis Treatment In A HIV-Infected Patients Cohort
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Ibandronate|BEHAVIORAL: Lifestyle modifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: Docetaxel|DRUG: Vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Modified Vaccinia Virus to Cancer
Status: COMPLETED
Conditions: Melanoma|Breast Cancer|Head and Neck Squamous Cell Cancer|Liver Cancer|Colorectal Cancer|Pancreatic Adenocarcinoma
Interventions: BIOLOGICAL: Vaccinia virus (vvDD-CDSR)|BIOLOGICAL: Vaccinia virus (vvDD-CDSR)|BIOLOGICAL: Vaccinia virus (vvDD-CDSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiparasitic Treatment for Returning Travelers With Chronic Diarrhea
Status: UNKNOWN
Conditions: Chronic Diarrhea|Abdominal Pain|Bloating
Interventions: DRUG: Tinidazole and Albendazole|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes
Status: TERMINATED
Conditions: Proteinuria|Hypertension|Type II Diabetes
Interventions: DRUG: Amiloride|DRUG: HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anti-hormonal Therapie With Ribociclib in HR-positive / HER2- Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Ribociclib|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MN4000 for Treatment of CF and MND Patients in the Home Setting
Status: COMPLETED
Conditions: Cystic Fibrosis|Motor Neuron Disease|Airway Clearance Impairment
Interventions: DEVICE: MN 4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Pomegranate Extract on Cognitive Function
Status: COMPLETED
Conditions: Mental Processes
Interventions: DIETARY_SUPPLEMENT: Pomegranate Extract|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PET/CT-directed Hyperfractionated Radiation Dose Escalation in Stage III Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: radiochemotherapy 1|RADIATION: radiochemotherapy 2|RADIATION: radiochemotherapy 3|RADIATION: radiochemotherapy 4|RADIATION: radiochemotherapy 5|RADIATION: radiochemotherapy 6|RADIATION: radiochemotherapy 7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Cariprazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Myocardial Infarction With Bone Marrow Derived Stem Cells
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Coronary catherization and stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy of Azacitidine +/- Lenalidomide in High-risk Myelodysplastic Syndrome (MDS)and Acute Myeloid Leukemia (AML) With Del(5q).
Status: UNKNOWN
Conditions: Myelodysplastic Syndrome|Acute Myelogenous Leukemia
Interventions: DRUG: Azacitidine|DRUG: azacitidine + lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of S26E for Diabetic Foot Ulcer Healing
Status: TERMINATED
Conditions: Diabetic Foot|Neuropathic Foot Ulcer|Chronic Diabetic Ulcer of Left Foot (Diagnosis)|Chronic Diabetic Foot Ulcer of Right Foot
Interventions: OTHER: Standard-of-care for neuropathic/neuroischemic diabetic foot ulcers|DRUG: S26E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: rituximab [MabThera/Rituxan]|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Liver Failure|Acute Liver Injury, Drug Induced
Interventions: COMBINATION_PRODUCT: miroliverELAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse Suicide: Physiologic Sleep Health Promotion Trial
Status: RECRUITING
Conditions: Suicide|Nurse's Role|Work Environment Adverse Effects|Sleep|Stress|Mental Health Wellness 1
Interventions: BEHAVIORAL: PureSomni Sleep Health Product Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Electrocardiogram (ECG) Guided Peripherally Inserted Central Catheter (PICC) Placement
Status: TERMINATED
Conditions: Primary Focus: Adult Subjects Who Require PICC Placement
Interventions: DEVICE: ECG-guided PICC placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Four-fragment Fractures of the Proximal Humerus: the Interest of 2D and 3D Imagery and Inter- and Intra-observer Reproducibility
Status: COMPLETED
Conditions: Reproducibility|Four Part Fracture|Proximal Humerus Fracture|Hertel's Criteria
Interventions: OTHER: Analysis of radiology (standard radiographies, 2D scan sections and 3D reconstructions)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Education on Neurophysiology of Pain Combined to Hypnosis in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: education|OTHER: education combined with hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project CORE: Disseminating Eating Disorders Treatment
Status: UNKNOWN
Conditions: Anorexia Nervosa/Bulimia|Anorexia Nervosa Restricting Type|Eating Disorders in Adolescence
Interventions: BEHAVIORAL: Family Based Treatment|BEHAVIORAL: Enhanced Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of HG004 for Leber Congenital Amaurosis Related to Rpe65 Gene Mutations (STAR)
Status: RECRUITING
Conditions: Leber Congenital Amaurosis|Inherited Retinal Diseases Caused by RPE65 Mutations
Interventions: DRUG: HG004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Risk Reduction|Alcohol Abuse|Depression, Anxiety|Behavior, Sex
Interventions: BEHAVIORAL: Comunică|OTHER: Education Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Omacor and Cardiovascular Risk Factors in HIV Patients on HAART Treatment
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Ischemic Heart Disease
Interventions: DRUG: Omega-3-acid ethyl esters 90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide Effects on Memory in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cancer in Patients With Gabapentin (GPRD)
Status: COMPLETED
Conditions: Pain, Neuropathic|Epilepsy|Renal Pelvis Cancer|Pancreatic Cancer|Breast Cancer|Nervous System Cancer|Chronic Pancreatitis|Stomach Cancer|Renal Cell Carcinoma|Diabetes|Bladder Cancer|Bone and Joint Cancer|Penis Cancer|Anal Cancer|Cancer|Renal Cancer
Interventions: DRUG: Gabapentin prescriptions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MPO Inhibitor A_Zeneca for HFpEF
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: AZD4831 Oral Myeloperoxidase Inhibitor|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of EMT Indicators in Healthy and Periodontally Diseased Gingival Samples
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Gingival tissue samples will be harvested
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Vision Disturbances Due to Corneal Irregularities by Trans-epithelial Optical Phototherapeutic Keratectomy (TE-oPTK)
Status: UNKNOWN
Conditions: Corneal Astigmatism
Interventions: PROCEDURE: Trans-epithelial PTK|DEVICE: EpiMaster Application Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
Status: RECRUITING
Conditions: Carotid Artery Stenosis|Glioma|Intracranial Aneurysm|Intracranial Hemorrhages|Brain Tumor
Interventions: DIAGNOSTIC_TEST: biological samples analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Status: RECRUITING
Conditions: Surgery-Complications|Anesthesia Complication|Anesthesia Awareness|Anesthesia|Surgery|Quality of Life|Pain, Postoperative|Anesthesia Morbidity
Interventions: OTHER: Anesthetic technique Propofol TIVA|OTHER: Anesthetic technique inhaled agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Aglatimagene besadenovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial
Status: COMPLETED
Conditions: Dementia, Vascular
Interventions: DRUG: Tadalafil|DRUG: Placebo|BEHAVIORAL: Cognitive functioning tests|BEHAVIORAL: Neuropsychological tests|OTHER: MRI Scan - Arterial Spin Labelling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Drug-Drug Interaction Study Between EDP-514, Itraconazole, Carbamazepine, and Quinidine in Healthy Subjects
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: EDP-514|DRUG: EDP-514|DRUG: EDP-514|DRUG: Itraconazole|DRUG: Carbamazepin|DRUG: Quinidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Direct Peritoneal Resuscitation in Gastroschisis
Status: TERMINATED
Conditions: Gastroschisis
Interventions: PROCEDURE: SoC Staged Silo Closure|DRUG: Peritoneal Dialysis Solution/Dextrose 1.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of Oral Nutritional Supplements (ONS) in a Meals-on-Wheels Population
Status: COMPLETED
Conditions: Elderly|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Ensure Plus|DIETARY_SUPPLEMENT: Meals on Wheels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrolyzed Collagen in the Reduction of Osteoarticular Pain and Functional Limitation
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed Collagen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Median Nerve Stimulation for Tourette Syndrome and Chronic Tic Disorder
Status: COMPLETED
Conditions: Tourette Syndrome|Chronic Tic Disorder
Interventions: DEVICE: Active stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ABM-1310 in Patients With BRAF V600-Mutant Relapsed and Drug Resistant Primary Malignant Brain Tumors
Status: RECRUITING
Conditions: Primary Malignant Brain Tumor
Interventions: DRUG: ABM-1310
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Long-term, Extension Treatment Using Intra-Erythrocyte Dexamethasone Sodium Phosphate in Patients With Ataxia Telangiectasia Who Participated in the IEDAT-02-2015 Study
Status: RECRUITING
Conditions: Ataxia Telangiectasia
Interventions: COMBINATION_PRODUCT: EryDex System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Influenza Vaccines Containing an Additional H3 Antigen in Healthy Adult Participants 18 to 49 Years of Age and 60 Years of Age and Older
Status: NOT_YET_RECRUITING
Conditions: Influenza|Healthy Volunteers
Interventions: BIOLOGICAL: Trivalent-Darwin influenza vaccine|BIOLOGICAL: Augment-Tasmania influenza vaccine|BIOLOGICAL: TIV-2X Darwin influenza vaccine|BIOLOGICAL: Trivalent-Tasmania influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Glutamate and Glutamine Metabolism in Burn Patients Receiving Enteral or Parenteral Nutrition
Status: WITHDRAWN
Conditions: Burns
Interventions: DRUG: standard vs. glutamine enteral or parenteral feeding.|DIETARY_SUPPLEMENT: Stable isotope tracer study|DIETARY_SUPPLEMENT: Stable isotope study|DIETARY_SUPPLEMENT: Stable isotope tracer study|DIETARY_SUPPLEMENT: Stable isotope tracer study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peroperative Effect of Regional Anesthesia in Hip Surgery
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Pericapsular Nerve Group Block|PROCEDURE: Lumber Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metoclopramide to Treat Anemia in Patients With Myelodysplastic Syndrome (MDS)
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Metoclopramide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Clinical Analysis of Ultrasound-guided Biceps Corticosteroid Injections
Status: TERMINATED
Conditions: Biceps Tendonitis|Injection
Interventions: PROCEDURE: Ultrasound-guidance|PROCEDURE: Landmark-guidance|DRUG: Methylprednisolone|DRUG: Lidocaine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)
Status: ACTIVE_NOT_RECRUITING
Conditions: In-Stent Restenosis
Interventions: DEVICE: AGENT DCB|DEVICE: PTCA balloon catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Axillary Versus Primary Breast Approach for Second-stage Breast Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasm Female|Breast Reconstruction|Wound Complication
Interventions: PROCEDURE: implant exchange operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HIHO Study: Hospital Inpatient vs Home Rehabilitation After Total Knee Replacement
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Hospital Inpatient Rehabilitation|OTHER: Hybrid Home Programme (HO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilateral Transcutaneous Tibial Nerve Stimulation on Postpartum Constipation
Status: UNKNOWN
Conditions: Constipation
Interventions: OTHER: Experimental: bilateral transcutaneous tibial nerve stimulation,exercise and advices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma
Status: TERMINATED
Conditions: Stage IV Melanoma|Stage III Melanoma
Interventions: BIOLOGICAL: Autologous Dendritic Cell-Tumor Cell Immunotherapy (DC-TC)|BIOLOGICAL: Autologous PBMCs in GM-CSF (MC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Cold Acclimation Stimulates the Browning of Subcutaneous White Adipose in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes|Cold Acclimation
Interventions: OTHER: Chronic cold acclimation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PPAR-gamma Agonists, Rheumatoid Arthritis and Cardiovascular Disease
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: pioglitazone|DRUG: Sublingual nitroglycerine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula
Status: COMPLETED
Conditions: Pancreatic Leak|Pancreatic Fistula|Pancreaticoduodenal; Fistula|Pancreatectomy; Hyperglycemia
Interventions: DRUG: Lanreotide Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biomarkers of Recurrence and Progression in Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Non-muscle Invasive Bladder Cancer|Cystoscopy|Recurrence|Progression|Bladder Cancer|Biomarkers
Interventions: DIAGNOSTIC_TEST: Blood serum: sUPAR, PAI-1, IL-8.|DIAGNOSTIC_TEST: Urine: IL-8, APOE, VEGF.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standardized and Modified Corticosteroid Subacromial Injection for Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement
Interventions: PROCEDURE: Subacromial injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Consequences of Gastrointestinal Surgery
Status: TERMINATED
Conditions: Gastrectomy|Oesophagectomy|Dumping Syndrome|Hypoglycaemia
Interventions: DRUG: Somatostatin|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of a Low-Carbohydrate Diet to Improve Maternal Health After Childbirth
Status: TERMINATED
Conditions: Obesity|Postpartum Weight Retention|Insulin Sensitivity
Interventions: BEHAVIORAL: Low carbohydrate diet education|BEHAVIORAL: Low carbohydrate diet education with behavioral component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creatine and Glutamine in Steroid-Naive Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: Creatine Monohydrate|DRUG: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Four Oral Prototype Extended Release Formulations With BI 11634 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 11634 ER formulation A|DRUG: BI 11634 ER formulation B|DRUG: BI 11634 ER formulation M|DRUG: BI 11634 ER formulation C|DRUG: BI 11634 IR tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Educational Tool for FM
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: PNE-explained group|BEHAVIORAL: PNE-read group|BEHAVIORAL: TAU group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine MTD, Evaluate Efficacy and Safety of Genexol®-PM Plus Carboplatin With Advanced Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Genexol-PM 220mg/㎡, Carboplatin 5AUC|DRUG: Genexol-PM 260mg/㎡, Carboplatin 5AUC|DRUG: Genexol-PM 300mg/㎡, Carboplatin 5AUC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection
Status: RECRUITING
Conditions: Epstein-Barr Virus Infections|Primary Immune Deficiency Disorder
Interventions: DRUG: cytotoxic t-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cross-over Study Examining the Bioequivalence of 3 Test Formulations to a Reference Formulation of Alectinib (RO5424802) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Ro542-4802/F03 (Reference)|DRUG: Ro542-4802/F07 (Test)|DRUG: Ro542-4802/F08 (Test)|DRUG: Ro542-4802/F14 (Test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gender and Proper Size of Oropharyngeal Airway: Pilot Study
Status: COMPLETED
Conditions: Adult Patients Undergoing Surgery That Requires General Anesthesia
Interventions: DEVICE: No. 7 oral airway|DEVICE: No. 8 oral airway|DEVICE: No. 9 oral airway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosomatic Intervention in Fibromyalgia.
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: psychosomatic intervention based on cognitive restructuring.|BEHAVIORAL: Control condition|OTHER: Experimental and control condition: Museum therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of 4D 18F-FDG PET-CT in Radiotherapy for Non Small Cell Lung Cancers
Status: COMPLETED
Conditions: Lung Cancer|Non-small-cell Lung Carcinoma
Interventions: DEVICE: CT-simulation and 4D PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identification of Compound Isolated From Cock's Comb and Its Effect on Arsenical Palmar Keratosis
Status: UNKNOWN
Conditions: Improvement of Keratotic Nodular Size
Interventions: DRUG: drug containing extract from cock's comb
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation
Status: NOT_YET_RECRUITING
Conditions: Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)|Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Ivosidenib|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self- Versus Conventional-swabbing for COVID-19 Screening (COVISWAB)
Status: UNKNOWN
Conditions: Covid19
Interventions: OTHER: nasopharyngeal swabbing procedure (self swabbing first)|OTHER: nasopharyngeal swabbing procedure (conventionnal swabbing first)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Determine Safety, Tolerability and Pharmacokinetics, of SCO-120 in Healthy Male and Post-menopausal Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: SCO-120|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Novel Self-Adhesive Composite Hybrid Versus Conventional Composite in Restoration of Carious Primary Teeth.
Status: UNKNOWN
Conditions: Dental Caries in Children
Interventions: OTHER: Novel self-adhesive hybrid composite(Surefil one)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2
Status: COMPLETED
Conditions: Hypoxic Pulmonary Vasoconstriction|Hypoxemia|Acute Respiratory Distress Syndrome|SARS-CoV-2 Acute Respiratory Disease
Interventions: DRUG: Effects in oxygenation and hypoxic pulmonary vasoconstriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of hMaxi-K Gene Transfer to Treat Overactive Bladder and Detrusor Overactivity
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: DRUG: hMaxi-K|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Verification of the Efficacy/Safety of the Intratympanic Drug Delivery for Hearing Loss
Status: RECRUITING
Conditions: Hearing Loss, Sudden|Hearing Loss, Ototoxic|Hearing Loss, Noise-Induced|Meniere Disease
Interventions: DRUG: Dexamethasone|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation
Status: UNKNOWN
Conditions: End Stage Liver DIsease|Liver Transplant; Complications|Liver Cirrhosis
Interventions: DRUG: Normal saline|DRUG: Balanced crystalloid solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Itraconazole Pharmacokinetic With and Without Efavirenz Using the Capsule Formulation as Part of Talaromycosis Treatment in HIV-infected Adults
Status: UNKNOWN
Conditions: Pharmacokinetics|Efavirenz|Penicilliosis
Interventions: OTHER: Pharmacokinetic study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease
Status: UNKNOWN
Conditions: Autonomic Nervous System Disease|Amyloid Neuropathies
Interventions: DIAGNOSTIC_TEST: Head-Up Tilt table test|DIAGNOSTIC_TEST: Heart Rate Variability
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HL-085+Vemurafenib to Treat Advanced Melanoma Patients With BRAF V600E/K Mutation
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: HL-085|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Staple Versus Suture Closure for Foot and Ankle Surgery
Status: WITHDRAWN
Conditions: Incision|Foot Ankle Injuries
Interventions: DEVICE: Metal skin staples|DEVICE: Nylon sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Prospective Randomized Trial of Efficacy of Stump Closure for Distal Pancreatectomy
Status: UNKNOWN
Conditions: Pancreatic Fistula
Interventions: PROCEDURE: Stump closure using NU-KNIT SURGICEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pomegranate Juice (PJ) on Oxidative Stress Biomarkers During Treatment With IV Iron During One Dialysis Session
Status: COMPLETED
Conditions: Cardiovascular Disease (CVD)
Interventions: DIETARY_SUPPLEMENT: PJ|DRUG: IV iron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
Status: RECRUITING
Conditions: Neuropathy in Cacer Patien
Interventions: DRUG: Duloxetine alone|DRUG: Duloxetine augmented with gabapentin|DRUG: Duloxetine augmented with amitriptyline (as combined therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saline Sonohystrography and Office Hysteroscopy in Evaluation of Cases of Abnormal Uterine Bleeding
Status: UNKNOWN
Conditions: Gynecologic Disease
Interventions: DEVICE: 3D saline infusion sonohysterography|DEVICE: Office Hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Melatonin for Circadian Sleep Disorders in the Blind
Status: TERMINATED
Conditions: Insomnia|Blindness|Daytime Sleepiness
Interventions: DRUG: Melatonin|BEHAVIORAL: Regular Sleep Schedule|BEHAVIORAL: Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Live Birth Rate Between the PPOS and the GnRH Antagonist Protocol in Patients Undergoing IVF
Status: RECRUITING
Conditions: Infertility|ART
Interventions: DRUG: Duphaston|DRUG: Cetrorelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study the Impact of Statins in Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Stage I, II, or IIIA Non-small Cell Lung Cancer That Has Been Surgically Removed
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety, Reactogenicity & Immunogenicity Study to Evaluate a Booster Dose of GSK Biologicals' Hib-MenC Given With Priorix™ in Toddlers (13-14 m) Primed With 3 Doses of Hib and MenC-CRM197
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: Haemophilus influenzae type b- and meningococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections|Chickenpox
Interventions: DRUG: Sorivudine|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Aruba Aloë Formula F-BC-096 in the Treatment of Split Thickness Donor Sites After Wound Closure
Status: WITHDRAWN
Conditions: Hydration of Scars
Interventions: DRUG: Application of Aruba Aloë formula F-BC-096 or control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function.
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: PF-07321332/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media.
Status: RECRUITING
Conditions: Healthy Subjects|Mental Health Issue
Interventions: BEHAVIORAL: Music composition / edition|BEHAVIORAL: Photography composition / edition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Providing Oxygen During Intubation in the NICU Trial
Status: RECRUITING
Conditions: Neonatal Respiratory Failure|Tracheal Intubation Morbidity
Interventions: PROCEDURE: Apneic Oxygenation|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Response to a Delayed Second Dose of Oral Cholera Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholera|Vibrio Cholerae Infection
Interventions: BIOLOGICAL: Delayed second dose of oral cholera vaccine, Euvichol-Plus|BIOLOGICAL: Oral cholera vaccine, Euvichol-Plus, according to manufacturer notice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Change in Executive Function and IADL Using a Virtual Supermarket Environment Among People With MCI
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Lack of Physical Activity
Interventions: BEHAVIORAL: Virtual Action Planning Supermarket (VAP-S) Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hourly Titrated Misoprostol Versus Vaginal Dinoprostone and Misoprostol for Cervical Ripening and Labor Induction
Status: UNKNOWN
Conditions: Labor, Induced
Interventions: DRUG: Oral misoprostol|DRUG: Vaginal misoprostol|DRUG: Vaginal dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)
Status: RECRUITING
Conditions: Cancer|Cancer Metastatic|NTRK Gene Fusion Overexpression|NTRK Family Gene Mutation|ATIC-ALK Fusion Protein Expression|ALK Fusion Protein Expression|BCR-FGFR1 Fusion Protein Expression|ROS1 Gene Translocation|COL1A1-PDGFB Fusion Protein Expression|RET Gene Translocation|Gene Fusion|ROS Gene Translocation|BRAF Gene Rearrangement|FGFR2 Gene Translocation|FGFR3 Gene Translocation|NTRK1 Gene Translocation
Interventions: OTHER: Data collection and quality of life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Topical application of curenext gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Isosorbide Mononitrate on Hypertension to Improve Left Ventricular Hypertrophy, Fibrosis and Myocardial Function
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Isosorbide Mononitrate, sustained release|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of ²¹²Pb-TCMC-Trastuzumab Radio Immunotherapy
Status: COMPLETED
Conditions: Breast Neoplasms|Peritoneal Neoplasms|Ovarian Neoplasms|Pancreatic Neoplasms|Stomach Neoplasms
Interventions: OTHER: ²¹²Pb-TCMC-Trastuzumab|BIOLOGICAL: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BVS Implantation in Patients With Variant Angina and MODerate Coronary Artery Disease
Status: WITHDRAWN
Conditions: Angina Pectoris, Variant
Interventions: DEVICE: BVS+OMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Stress Urinary Incontinence.
Status: COMPLETED
Conditions: Urinary Incontinence,Stress
Interventions: DEVICE: Non-ablative vaginal Erbium YAG laser treatment|OTHER: PFE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT