pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brain Mechanisms of Video-Guided Acupuncture Imagery Treatment on Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: OTHER: Verum VGAIT (Video-Guided Acupuncture Imagery Treatment)|OTHER: Sham VGAIT (Video-Guided Acupuncture Imagery Treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Autogenous Stored Versus Autogenous Fresh Mineralized Dentin Graft for Alveolar Ridge Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Autogenous stored mineralized dentin graft (ASMDG)|PROCEDURE: Autogenous fresh mineralized dentin graft (AFMDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: AR-12286 0.5% ophthalmic solution|DRUG: AR-12286 0.25% Ophthalmic solution|DRUG: Latanoprost ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)
Status: TERMINATED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Cadazolid|DRUG: Vancomycin capsule|DRUG: Vancomycin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Protected Full Weight-bearing vs. Partial Weight-bearing After Surgical Fixation of Unstable Ankle Fractures, Monitored With Bio-feedback Insoles.
Status: NOT_YET_RECRUITING
Conditions: Post Operative Treatment After Unstable Malleolar Fractures
Interventions: OTHER: Full weight bearing|OTHER: Partial weight bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Digital Tools on the Quality of Bowel Preparation for Colonoscopy
Status: NOT_YET_RECRUITING
Conditions: Colonoscopy
Interventions: OTHER: Standard of care|OTHER: Standard of care + Video call|OTHER: Standard of care + Video call + Educational video film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus K Drug in the Treatment of First-line Non-small Cell Lung Cancer(NSCLC)
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: TQB2450 injection|DRUG: Anlotinib Hydrochloride Capsules|DRUG: Pembrolizumab injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Gluteal Fascio-myo-cutaneous Flap in Treatment of Recurrent Pilonidal Disease
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Bilateral Gluteal Advancement Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Meditation on Stress and Rumination Following Objective Structured Clinical Examination (OSCE)
Status: COMPLETED
Conditions: Stress, Psychological|Stress, Physiological|Rumination|Exam Stress
Interventions: OTHER: Meditation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Maternal Consumption of Xylitol to Reduce Early Childhood Decay (MaXED Study)
Status: UNKNOWN
Conditions: Dental Caries|Oral Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Xylitol consumption|BEHAVIORAL: Childsmile preventative programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Rosuvastatin on Aortic Stiffness in Hemodialysis Patients in the AURORA Study
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|PROCEDURE: aortic pulse wave velocity measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Tailored Nutritional Education Program on Profound Hearing Impairment Adults
Status: RECRUITING
Conditions: Profound Hearing Impairment|Nutrition, Healthy
Interventions: DEVICE: Tailored nutritional education program utilizing Saudi-sign language supplied by Saudi-sign language interpreter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Movement Disorders Caused by Antipsychotic Drugs in Older Patients
Status: COMPLETED
Conditions: Dyskinesia, Drug-Induced
Interventions: DRUG: Quetiapine|DRUG: Risperidone|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Study of IGIV, 10% in Alzheimer´s Disease
Status: TERMINATED
Conditions: Alzheimer´s Disease
Interventions: DRUG: Immune Globulin Intravenous (Human), 10% (IGIV, 10%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Combined With Intermittent Oral to Esophageal Tube on Dysphagia
Status: RECRUITING
Conditions: Cerebral Infarction
Interventions: BEHAVIORAL: Comprehensive rehabilitation therapy|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Focused Play Intervention for Children With ADHD
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Playing the game|BEHAVIORAL: Watching the gameplay video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consciousness, Psilocybin, and Well-Being
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Psychedelic Experiences|Sleep
Interventions: DRUG: Psilocybin|DRUG: Clonidine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chidamide in Combination With Carboplatin and Paclitaxel in Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Chidamide|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Peripheral Veins Doppler Ultrasound for Diagnosis of Acute Right Heart Failure in Suspicion or Follow-up of Pulmonary Hypertension
Status: COMPLETED
Conditions: Acute Right Heart Failure|Pulmonary Hypertension|Peripheral Veins Doppler Ultrasound
Interventions: DIAGNOSTIC_TEST: Peripheral veins Doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PA Behavior and HRQoL in Parkinson's Disease Patients Patients: Role of Social Cognitive Variables
Status: COMPLETED
Conditions: Parkinson Disease|Idiopathic Parkinson Disease|Idiopathic Parkinson's Disease|Parkinson Disease, Idiopathic|Parkinson's Disease|Parkinson's Disease, Idiopathic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Pudendal Block in Transurethral Prostatectomies
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Pudendal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ADX10059 as a Monotherapy in Patients With Gastroesophageal Reflux (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: ADX10059|DRUG: ADX10059 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Hepatic Function and Subjects With Moderate Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Hydrocodone bitartrate extended-release tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention and Treatment of Injuries and Urinary Incontinence Among Norwegian Rhythmic Gymnasts
Status: ACTIVE_NOT_RECRUITING
Conditions: Overuse Injury|Urinary Incontinence
Interventions: OTHER: Exercises for knees, lower back, hip/groin and pelvic floor muscles in an expanded warm up program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease
Status: NOT_YET_RECRUITING
Conditions: Buerger Disease|Raynaud Syndrome
Interventions: DRUG: BOTOX INJECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=60)
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: Exforge tab. 10/160mg|DRUG: Lodivixx tab. 5/160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: 7-day sleep lab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Mild-to-moderate Hypoglycemia in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Test to induce a decline in plasma glucose|DEVICE: Dexcom G6|OTHER: Dex4|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men
Status: ACTIVE_NOT_RECRUITING
Conditions: Anal Carcinoma|HIV Infection|Human Papillomavirus Infection
Interventions: PROCEDURE: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Inflammatory Targeted Laser Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Exercise therapy|OTHER: LLLT|OTHER: Sham LLLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron Oral Suspension in Pediatric Subjects From 3 to Less Than 12 Years of Age With Neurogenic Detrusor Overactivity (NDO) or Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Overactive Bladder|Neurogenic Detrusor Overactivity
Interventions: DRUG: mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transplantation of Hematopoietic Stem Cells From HLA-compatible Donors in Patients With B-Cell Lymphoid Malignancies
Status: WITHDRAWN
Conditions: B-Cell Lymphoid Malignancies|Hematologic Malignancy|Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Hematopoietic Stem Cells from HLA-compatible Related|BIOLOGICAL: Hematopoietic Stem Cells from HLA Unrelated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chronic Statin and Viagra Therapy in Persons With Endothelial Cell Dysfunction
Status: WITHDRAWN
Conditions: Endothelial Dysfunction
Interventions: DRUG: Atorvastatin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Keynatinib in Treated Patients With NSCLC and Brain Metastases
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer With EGFR Mutation|Brain Metastases
Interventions: DRUG: Keynatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Contrast-Induced Nephropathy in Diabetic Patients With Undergoing Coronary Angiography
Status: UNKNOWN
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: Sodium bicarbonate|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Perceval S Aortic Heart Valve Study- North America
Status: TERMINATED
Conditions: Aortic Valve Stenosis|Aortic Valve Stenosis With Insufficiency|Regurgitation, Aortic Valve|Aortic Valve Incompetence
Interventions: DEVICE: Perceval S Aortic Heart Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mp-3TMRI and 68Ga-PSMA PET/CT Guided Prostate Biopsy and Tumor Node Metastasis (TNM) Staging.
Status: RECRUITING
Conditions: 68Ga-PSMA PET/CT Guided Prostate Biopsy|Mp-3TMRI Guided Prostate Biopsy|Prostate Cancer|TNM Staging|Diagnosis
Interventions: DIAGNOSTIC_TEST: pelvic MRI|DIAGNOSTIC_TEST: 68Ga-PSMA PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Bladder Filling vs. Non-Filling in Cesarean Hysterectomy for Placenta Percreta
Status: UNKNOWN
Conditions: Placenta Accreta
Interventions: PROCEDURE: Filled-bladder|PROCEDURE: non filled-bladder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization of the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of APR-TD011® (RLF-TD011®) Spray Solution
Status: NOT_YET_RECRUITING
Conditions: Cutaneous T Cell Lymphoma
Interventions: COMBINATION_PRODUCT: APR-TD011 (RLF-TD011)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Labor Analgesia Between Modified Combined Spinal-Epidural and Dural Puncture Epidural Techniques
Status: UNKNOWN
Conditions: To Determine the Onset of Analgesia (Numerical Rating Scale for Pain = 1) in Minutes
Interventions: PROCEDURE: Modified CSE|PROCEDURE: Dural puncture epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Major Depressive Disorder
Status: RECRUITING
Conditions: Depression|Treatment Resistant Depression
Interventions: BIOLOGICAL: FMT oral Capsules|BIOLOGICAL: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iMagIng pulmonaRy Aspergillosis Using Gallium-68-dEferoxamine
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Aspergillosis|Chronic Pulmonary Aspergillosis|Allergic Bronchopulmonary Aspergillosis
Interventions: OTHER: Radiopharmaceutical: gallium-68-deferoxamine ([68Ga]Ga-DFO-B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cellular and Molecular Events During Treatment of Actinic Keratosis With Imiquimod 5% Cream
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aldara (imiquimod 5% cream)|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of TH-302 in Combination With A) Gemcitabine or B) Docetaxel or C) Pemetrexed to Treat Advanced Solid Tumors
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Prostate Cancer|Pancreatic Cancer
Interventions: DRUG: TH-302
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Registry of Oncology Outcomes Associated With Testing and Treatment
Status: RECRUITING
Conditions: Adenocarcinoma|Adenocystic Carcinoma|Anal Cancer|Appendix Cancer|Brain Tumor|Glioblastoma|Astrocytoma|Bile Duct Cancer|Cholangiocarcinoma|Bladder Cancer|Bone Cancer|Synovial Sarcoma|Chondrosarcoma|Liposarcoma|Sarcoma, Kaposi|Sarcoma,Soft Tissue|Sarcoma|Osteosarcoma|CNS Cancer|Brain Stem Neoplasms|Breast Cancer|Cervical Cancer|Colorectal Cancer|Rectal Cancer|Colon Cancer|Esophageal Cancer|Esophagus Cancer|Cancer of Colon|Pancreatic Cancer|Cancer of Pancreas|Testis Cancer|Testicular Cancer|Ureter Cancer|Renal Cell Carcinoma|Kidney Cancer|Gestational Trophoblastic Tumor|Head and Neck Neoplasms|Parotid Tumor|Larynx Cancer|Tongue Cancer|Pharynx Cancer|Salivary Gland Cancer|Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia|Multiple Myeloma|Non Hodgkin Lymphoma|Carcinoid Tumor|Lung Cancer|Neuroendocrine Tumors|Mesothelioma|Thyroid Cancer|Parathyroid Neoplasms|Adrenal Cancer|Small Bowel Cancer|Stomach Cancer|Liver Cancer|Hepatic Cancer|Melanoma|Skin Cancer|Unknown Primary Tumors|Uterine Cancer|Fallopian Tube Cancer|Ovarian Cancer|Prostate Cancer|Vaginal Cancer|Penile Cancer|Vulvar Cancer|Waldenstrom Macroglobulinemia|Cancer, Advanced|Thymus Cancer|Nasopharyngeal Carcinoma|Multiple Endocrine Neoplasia|Pheochromocytoma|Small Cell Carcinoma|Pulmonary Carcinoma
Interventions: DIAGNOSTIC_TEST: Biomarker Testing (L)|DRUG: Systemic Treatment (T)|OTHER: Patient Reported Outcomes (P)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LY353381 in Preventing Breast Cancer in Women With Hyperplasia
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: arzoxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Vascular Disease|Critical Limb Ischemia
Interventions: DRUG: Dexamethasone infusion|DEVICE: Drug coated balloon|DEVICE: Plain balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dielectric Property Test Compared With Frozen Pathological Section in the Rapid Diagnosis of Lung Nodules/Mass
Status: UNKNOWN
Conditions: Lung Nodules|Lung Mass
Interventions: DIAGNOSTIC_TEST: dielectric property test|DIAGNOSTIC_TEST: frozen pathological examination|DIAGNOSTIC_TEST: final pathological examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fludarabine Plus Octreotide in Treating Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: fludarabine phosphate|DRUG: octreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to Ustekinumab for Anti-tnf Induced Psoriasiform Skin Lesions
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Psoriasis
Interventions: DRUG: Ustekinumab|DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Multiple Attacks of Acute Migraine (0462-025)
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: rizatriptan benzoate|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss
Status: COMPLETED
Conditions: Weight Loss|Ovarian Carcinoma|Endometrial Carcinoma
Interventions: OTHER: Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Status: RECRUITING
Conditions: Diffuse Astrocytoma, IDH-Mutant|Glioblastoma, IDH-wildtype|Brain Metastases, Adult|Cervical Cancer|Colorectal Cancer|Esophageal Cancer|Esophageal Squamous Cell Carcinoma|Gastric Cancer|Gastroesophageal Junction Adenocarcinoma|Head and Neck Squamous Cell Carcinoma|Melanoma|Merkel Cell Carcinoma|Microsatellite Instability-High Solid Malignant Tumor|Mismatch Repair Deficient Solid Malignant Tumor|Microsatellite Instability-High Colorectal Cancer|Mismatch Repair Deficient Colorectal Cancer|Non-small Cell Lung Cancer|Renal Cell Carcinoma|Small Cell Lung Cancer|Squamous Cell Carcinoma|Urothelial Carcinoma
Interventions: DRUG: NEO212 Oral Capsule|DRUG: Ipilimumab|DRUG: Pembrolizumab|DRUG: Nivolumab|DRUG: Regorafenib|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: FOLFIRI Protocol|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Celiac Block Injection: 1 vs. 2
Status: COMPLETED
Conditions: Chronic Pancreatitis|Pancreatic Cancer
Interventions: OTHER: one injection into the celiac ganglion|OTHER: two injections into the celiac ganglion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Local Uterine Application of Low Molecular Weight Heparin (LMWH) in Intra-cytoplasmic Sperm Injection (ICSI)
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Enaoxaprin sodium|DRUG: tissue culture media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daratumumab and Belatacept for Desensitization
Status: RECRUITING
Conditions: Highly Sensitized Prospective Kidney Transplant Recipients
Interventions: BIOLOGICAL: daratumumab|BIOLOGICAL: belatacept|PROCEDURE: Bone marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn
Status: COMPLETED
Conditions: Depressive Symptoms|Parkinson's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
Status: RECRUITING
Conditions: Hyperkalemia
Interventions: DRUG: sodium zirconium cyclosilicate (SZC)|DRUG: sodium polystyrene sulfonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy
Status: COMPLETED
Conditions: Solar Lentigines
Interventions: DRUG: Tri-luma|PROCEDURE: Cryotherapy (CRY-AC3® device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnosis of Cow's Milk Protein Allergy Among Infants and Children in Assuit University Children Hospital
Status: UNKNOWN
Conditions: Cow Milk Allergy
Interventions: DIAGNOSTIC_TEST: skin prick test - specific serum IgE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
Status: COMPLETED
Conditions: Aging|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Peanut Protein Powder|BEHAVIORAL: Full body resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Training Program for Ambulatory Patients With Chronic Gait Deficits After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Virtual reality system (CAREN™ Integrated Reality System; MOTEK BV, Netherlands).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milnacipran (Savella) in Irritable Bowel Syndrome (IBS)
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Milnacipran|DRUG: Milnacipran|DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Tacrolimus 0.1% Topical Ointment Formulations in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tacrolimus 0.1% manufactured by Taro|DRUG: Protopic - Tacrolimus 0.1%|DRUG: Tacrolimus Vehicle manufactured by Taro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Renal Disease|Diabetes Mellitus|Metabolic Disease|Endocrine System Diseases
Interventions: DRUG: Evogliptin 5mg/Metformin 1000mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Chinese Healthy Adults to Evaluate the Safety, Tolerability and Pharmacokinetics on ZSP1601, and the Effect of Food on ZSP1601 Pharmacokinetics
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: ZSP1601 25 mg|DRUG: Placebo 25mg|DRUG: ZSP1601 50 mg|DRUG: Placebo 50 mg|DRUG: ZSP1601 100 mg|DRUG: Placebo 100 mg|DRUG: ZSP1601 175 mg|DRUG: Placebo 175 mg|DRUG: ZSP1601 275 mg|DRUG: Placebo 275 mg|DRUG: ZSP1601 350 mg|DRUG: Placebo 350mg|DRUG: ZSP1601 100 mg|DRUG: Placebo 100mg|DRUG: ZSP1601 50 mg|DRUG: Placebo 50 mg|DRUG: ZSP1601 100 mg|DRUG: Placebo 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Transcranial Magnetic Stimulation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preheated Skin Disinfection vs Room-temperature on Bacterial Colonization During Pace Device Implantation
Status: COMPLETED
Conditions: Colonization
Interventions: PROCEDURE: Preheated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PEPAF: Evaluation of Family Physician's Effectiveness for Physical Activity Promotion
Status: COMPLETED
Conditions: Exercise|Physical Fitness|Quality of Life
Interventions: BEHAVIORAL: Experimental Programme for Physical Activity Promotion|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Urge Incontinence|Overactive Bladder Syndrome|Urinary Incontinence, Urge|Urge Incontinence|Urinary Urgency|Urinary Frequency
Interventions: DRUG: OnabotulinumtoxinA 100 UNT [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: (Neo)Adjuvant BRAF/MEK Inhibition in pN1c Melanoma
Status: RECRUITING
Conditions: Melanoma Stage III|In-Transit Metastasis of Cutaneous Melanoma
Interventions: DRUG: Encorafenib + Binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study on the Validity of the Metacognitive Hub Model of Craving in Bulimia Nervosa (BN) and Binge Eating Disorders (BED)
Status: RECRUITING
Conditions: Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Food craving induction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: TC-5214|DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease
Status: RECRUITING
Conditions: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Minimal Residual Disease
Interventions: DRUG: Dasatinib|DRUG: Imatinib Mesylate|OTHER: Laboratory Biomarker Analysis|DRUG: Nilotinib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BGAT (Blood Glucose Awareness Training) for Users Who Might Become Pregnant
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Pregnancy
Interventions: BEHAVIORAL: Bump2be|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dynamic Surface Exercise and Trunk Targeted Training in Children With Spastic Cerebral Palsy
Status: RECRUITING
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: dynamic surface exercise|OTHER: trunk targeted training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INCB018424 in Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphocytic Leukemia|Myelodysplastic Syndrome|Chronic Myelogenous Leukemia
Interventions: DRUG: INCB018424
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placental Perfusion in the Entire Placenta and With Sonobiopsy by Ultrasound
Status: COMPLETED
Conditions: Placenta Diseases
Interventions: DIAGNOSTIC_TEST: 3 dimensional ultrasound investigation|DIAGNOSTIC_TEST: 2 dimensional ultrasound investigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Curcumin and Nanocurcumin in Oral Aphthous Ulcer
Status: COMPLETED
Conditions: Recurrent Aphthous Ulcer|Recurrent Aphthous Stomatitis
Interventions: OTHER: Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose or High Dose Frequency Study of Alglucosidase Alfa
Status: COMPLETED
Conditions: Pompe Disease|Glycogen Storage Disease Type II (GSD-II)|Glycogenesis 2 Acid Maltase Deficiency
Interventions: BIOLOGICAL: alglucosidase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hyperphosphatemia
Interventions: DRUG: Lanthanum Carbonate|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Efficacy and Safety of CMAB007 and Xolair® in Patients With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: CMAB007|DRUG: Xolair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Peritoneal Carcinomatosis
Interventions: PROCEDURE: HIPEC with neoadjuvant chemotherapy|PROCEDURE: Systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Breastmilk Alone or in Combination With Paracetamol for Reducing Pain
Status: UNKNOWN
Conditions: Pain Control
Interventions: DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC
Status: COMPLETED
Conditions: Bowen's Disease|Cutaneous Squamous Cell Carcinoma in Situ
Interventions: DRUG: STP705
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACell MatriStem Pelvic Floor Matrix Versus Native Tissue Repair, Comparative Study
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: MatriStem Pelvic Floor Matrix|PROCEDURE: native tissue repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium and Phosphorus Whole-Body Balance and Kinetics in Patients With Moderate Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Phosphorus and Calcium Disorders|Chronic Kidney Disease Mineral and Bone Disorder|Chronic Kidney Diseases
Interventions: OTHER: Low Calcium/High Phosphorus Diet|OTHER: High Calcium/Low Phosphorus Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Systemic Chemotherapy Versus Transcatheter Arterial Chemoembolization(TACE) for Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Pirarubicin|DRUG: Oxaliplatin|DRUG: Lipiodol|DEVICE: Gelfoam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Resumption of Anticoagulation in Patients With Both High Thrombosis Risk and Major HEmoRrhage
Status: TERMINATED
Conditions: Major hæmorrhage
Interventions: DRUG: UFH Early group|DRUG: UFH Late group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy Research of Uni- vs Bi-lateral Arm Training Poststroke
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Task-related unilateral arm training|BEHAVIORAL: Task-related bilateral arm training|BEHAVIORAL: Robot-assisted bilateral arm training|BEHAVIORAL: Robot-assisted unilateral arm training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mRNA Electroporated Autologous Dendritic Cells for Stage III/IV Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma Stage III|Malignant Melanoma Stage IV
Interventions: BIOLOGICAL: Dendritic cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Effect of Probiotics (Mutaflor®) in Patients With Ulcerative Colitis on 5-ASA Treatment.
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: E. coli Nissle 1917 (Mutaflor®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer
Interventions: BIOLOGICAL: TARA-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of TCLT in TBI Patients: a Prospective, Randomized Controlled Trial
Status: COMPLETED
Conditions: Brain Injury|Cognitive Deficits
Interventions: DEVICE: Transcranial LED Therapy (TCLT)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis With Inadequate Response to or for Whom Cyclosporine A is Not Medically Advisable
Status: WITHDRAWN
Conditions: Moderate-to-severe Atopic Dermatitis
Interventions: DRUG: Nemolizumab|DRUG: CD14152 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Evaluation of Levonorgestrel Implant and Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV|Contraception
Interventions: DRUG: Levonorgestrel|DRUG: Nevirapine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Platelet-enriched Plasma During Auricular Reconstruction
Status: UNKNOWN
Conditions: Ear Cartilage|Platelets|Microtia-Anotia
Interventions: PROCEDURE: Platelet enriched plasma administration|PROCEDURE: Placebo Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - Montpellier
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: portable artificial pancreas system with Control-To-Range algorithms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D Repletion in Stone Formers With Hypercalciuria
Status: COMPLETED
Conditions: Nephrolithiasis|Urolithiasis|Idiopathic Hypercalciuria|Vitamin D Deficiency|Disorder of Vitamin D
Interventions: DRUG: Ergocalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Transplant Maintenance Therapy With Isatuximab Plus Lenalidomide for High-Risk Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Rilvegostomig|DRUG: Placebo|DRUG: Capecitabine|DRUG: Gemcitabine/Cisplatin|DRUG: S-1 [Tegafur/Oteracil/gimeracil]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atraumatic Zirconia Abutment Versus Customized Composite Healing Abutment in Maxilla or Mandible.
Status: RECRUITING
Conditions: Dental Implants|Humans|Dental Implants, Single-Tooth|Male|Female|Osseointegration|Dental Anxiety|Guided Surgery
Interventions: PROCEDURE: Kompozite closure|PROCEDURE: Individual abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Head-to-head Comparison of Diagnosis Value of Pulmonary Fibrosis on 68Ga-FAPI-04 and 18F-FDG PET-CT
Status: UNKNOWN
Conditions: Pulmonary Fibrosis
Interventions: DRUG: 68Ga-FAPI|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carotid Artery Stenosis and Ischemic Cerebrovascular Events After Radiotherapy in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Carotid Artery Stenosis|Head and Neck Cancer|Radiation Therapy|Transient Ischemic Attack|Ischemic Stroke
Interventions: RADIATION: Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia
Status: UNKNOWN
Conditions: Gestational Trophoblastic Disease
Interventions: DRUG: rescue regimen|DRUG: high dose methotrxate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 7MW3711 in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: 7MW3711 for injection|DRUG: 7MW3711 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Left Paratrachéal Force Required to Occlude the Esophageal Entrance
Status: UNKNOWN
Conditions: Oesophageal Reflux
Interventions: DEVICE: Left paratracheal pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Physical Exercise Session Performed During a 24-34 Hour Fasting Period on Energy Metabolism and Cognitive Function in Healthy Adults
Status: RECRUITING
Conditions: Energy Metabolism
Interventions: BEHAVIORAL: 34-hour fasting in sedentary conditions|BEHAVIORAL: 34-hour fasting with high-intensity exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer
Status: UNKNOWN
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: AL2846|DRUG: Calcium folate|DRUG: 5-FU|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Supplementation on the Immune System in Patients With Ulcerative Colitis in Amman, Jordan
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Probiotic Formula Capsule|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System
Status: TERMINATED
Conditions: High Risk Prostate Carcinoma|Biochemically Recurrent Prostate Carcinoma|Castration-resistant Prostate Cancer|Prostate Cancer
Interventions: OTHER: Blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Tonsillectomy Pain Reduction Study
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: lidocaine (1%) + bupivacaine (0.5%)|DRUG: Normal saline|DRUG: Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT