pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Open Label Study of a Single Dose of a New Extended Long Acting Formulation of Octreotide Pamoate in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Cholecystectomized
Interventions: DRUG: Octreotide pamoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Status: NOT_YET_RECRUITING
Conditions: Coronary Bypass Graft Stenosis|Valvular Heart Disease
Interventions: PROCEDURE: robot-assisted surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interruptions in the Coagulationsystem in Relation With Cardiac Surgery - A Study Comparing Two Heparinization Strategies During On-pump Cardiac Surgery
Status: WITHDRAWN
Conditions: Cardiac Surgery
Interventions: DEVICE: Activated clotting time versus blood-heparin concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Triiodothyronine for Children Undergoing Cardiopulmonary Bypass in Indonesia
Status: COMPLETED
Conditions: Postoperative; Dysfunction Following Cardiac Surgery
Interventions: DRUG: Oral triiodothyronine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Altitude Related Illness In Patients With Respiratory Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Study of Doxorubicin Versus Epirubicin-induced Cardiotoxicity in Patients With DLBCL
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: CEOP regimen|DRUG: CHOP regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Splanchnic Venous Capacitance in Postural Tachycardia Syndrome
Status: RECRUITING
Conditions: Postural Tachycardia Syndrome (POTS)
Interventions: DIAGNOSTIC_TEST: Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls POTS patients|DIAGNOSTIC_TEST: Measurement of Splanchnic venous capacitance(SVC)done at Baseline and after 90 min of 75 g glucose in Healthy Controls|DRUG: Compare change is SVC and SMA flow due to GIP antagonist GIP(3-30)NH2|DRUG: Compare change is SVC and SMA flow due to saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Aerobics Training on Balance in Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Non Impact Aerobics|OTHER: Passive : lecture series
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation for Risk Reduction in Cancer Surgery
Status: RECRUITING
Conditions: Risk Reduction|Urological Cancer|Surgery|Life Style
Interventions: BEHAVIORAL: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the COVID-19 Pandemic on the Health Status of People Aged 75 and Over and Their Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|SARS-CoV-2 Infection|Caregivers|Frailty|Burden, Caregiver
Interventions: OTHER: Exposure SARS-CoV-2 Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prostate Artery Embolization: Single Center Experience
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia (BPH)|Lower Urinary Tract Symptoms
Interventions: OTHER: Prostate artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response and Cytomegalovirus in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: OTHER: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings|OTHER: Sampling of blood, phenotypic analysis sub-populations NK by cytometric of stream in multiple markings
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Source of Human Milk Fortifier and Intestinal Oxygenation in Preterm Infants <30 Weeks Gestation
Status: NOT_YET_RECRUITING
Conditions: Feeding; Difficult, Newborn
Interventions: DIETARY_SUPPLEMENT: Human milk-based HMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: BMX-001|RADIATION: Radiation Therapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inositol Supplementation to Treat PCOS (INSUPP-PCOS)
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Anovulation|Hyperandrogenism|Insulin Resistance|Glucose Intolerance|Metabolic Complication
Interventions: OTHER: Placebo|DRUG: Inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the hYpothermic Compression Bandage in the Surgical Wound of Cardiac Devices
Status: COMPLETED
Conditions: Pocket Hematoma
Interventions: PROCEDURE: hypothermic compression bandage|PROCEDURE: Conventional compression bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer|Resected Stage
Interventions: DRUG: Cetuximab|DRUG: CB-NK-TGF-Î²R2-/NR3C1|DRUG: Fludarabine phosphate|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE® ENFORM Biomaterial Product Study
Status: RECRUITING
Conditions: Hernia, Ventral|Hernia, Hiatal|Hernia, Diaphragmatic|Incisional Hernia
Interventions: DEVICE: Gore ENFORM Biomaterial (Preperitoneal)|DEVICE: Gore ENFORM Biomaterial (Intraperitoneal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic
Status: UNKNOWN
Conditions: Relapsed Acute Promyelocytic Leukemia|Refractory Acute Promyelocytic Leukemia
Interventions: DRUG: Arsenic trioxide|DRUG: Trisenox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citalopram as a Posterior Cortical Protective Therapy in Parkinson Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Citalopram 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: combined therapy using gemcitabine and cisplatin chemotherapy, Lenvatinib and Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for the Prevention of Radiodermatitis in Head and Neck Patients
Status: COMPLETED
Conditions: Head Cancer|Neck Cancer
Interventions: DEVICE: Low-level laser therapy|DEVICE: sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: mFOLFOX vs. mFOLFIRI in Advanced or Recurrent Biliary Tract Cancer Refractory to First Line
Status: COMPLETED
Conditions: Biliary Cancer Metastatic
Interventions: DRUG: Oxaliplatin,5FU, leucovorin|DRUG: irinotecan,5FU, leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Insufflated Gas on Core Temperature and Post-operative Pain During Laparoscopic Surgery
Status: COMPLETED
Conditions: Laparoscopy|Pain, Postoperative|Hypothermia
Interventions: DEVICE: Aeroneb® Pro (Nektar® Company)|DEVICE: Aeroneb® Pro (Nektar® Company)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Actonel® After Denosumab Discontinuation in Postmenopausal Osteoporosis Women
Status: RECRUITING
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Risedronate Sodium 35 MG [Actonel]|DRUG: Calcium Vitamin D combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerance of Cyto-selective Difluoroethane-based Cryotherapy
Status: COMPLETED
Conditions: Solar Lentigo
Interventions: DEVICE: Prototypes (812A-v1), (812C-v1), (812D-v1) and (812F-v1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Decisiveness of MFI-11 in Predicting Complications in Patients > 65 Years Who Underwent EBUS-TBNA Under Sedation
Status: COMPLETED
Conditions: Sedation Complication|EBUS Guided Transbronchial Needle Aspiration|Monitored Anesthesia Care|Elderly Patients
Interventions: OTHER: Modified Frailty Index -11
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DIalysis Symptom COntrol-Pruritus Outcome Trial
Status: COMPLETED
Conditions: End Stage Renal Disease|Pruritus
Interventions: DRUG: Nabilone 0.5 MG Oral Capsule|DRUG: Placebo Nabilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Workflow and Performance Evaluation of the THERMOCOOL SMARTTOUCH® SF-5D System for Treating Symptomatic Paroxysmal AF (QDOT-Micro)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: THERMOCOOL SMARTTOUCH® SF-5D catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Device "Gondola" for Motor Rehabilitation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: AMPS Gondola|DEVICE: Sham Gondola
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Nilotinib In Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Block for Postoperative Analgesia in Thoracoscopic Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: VATS|PROCEDURE: PVB using PVC|DRUG: PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Direct Laryngoscopy, Truview EVO2 and Glidescope in Pediatric Patients
Status: TERMINATED
Conditions: Intubation
Interventions: DEVICE: Macintosh blade|DEVICE: Glidescope|DEVICE: Truview PCD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Immunogenicity, Safety and Tolerability of Ad26.ZEBOV and MVA-BN-Filo in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.ZEBOV-Batch #1|BIOLOGICAL: Ad26.ZEBOV-Batch #2|BIOLOGICAL: Ad26.ZEBOV-Batch #3|BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Plant Sterol Enriched Milk on Plasma Lipid Levels of Humans Breast-fed During Infancy
Status: UNKNOWN
Conditions: Hypercholesterolemia|CVD
Interventions: OTHER: Plant Sterols|OTHER: High cholesterol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of Cryoablation in Management of Sialorrhea in Patients With Neurological Disorders
Status: WITHDRAWN
Conditions: Sialorrhea|Neurologic Disorder
Interventions: DEVICE: CRYOABLATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/IIa Study for AZD5335 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors
Status: RECRUITING
Conditions: Ovarian Cancer|Lung Adenocarcinoma
Interventions: DRUG: AZD5335|DRUG: AZD5305
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants
Status: RECRUITING
Conditions: Peri-Implantitis|Dental Implant Failed
Interventions: PROCEDURE: implant decontamination with titanium curette|DEVICE: implant decontamination with Air-Flow device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Cerebral Oximetry in Reducing Postoperative Morbidity Following Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: OTHER: Correction rSO2 desaturation.|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Investigational contact lens|DEVICE: PureVision contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Dexmedetomidine and Propofol for Patients in the Intensive Care Unit After Abdominal Surgery
Status: COMPLETED
Conditions: Microcirculation
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of Vi-DT (Diphtheria Toxoid) Typhoid Conjugate Vaccine (Phase III)
Status: COMPLETED
Conditions: Safety Issues|Immunogenicity
Interventions: BIOLOGICAL: Vi-DT Typhoid Conjugate Vaccine|BIOLOGICAL: PQed Typhoid Conjugate Vaccine|BIOLOGICAL: Vi Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer
Status: COMPLETED
Conditions: Recurrent Salivary Gland Cancer|Stage IVA Salivary Gland Cancer|Stage IVB Salivary Gland Cancer|Stage IVC Salivary Gland Cancer
Interventions: DRUG: eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-P16-093 PET/CT Imaging in the Salivary Gland
Status: NOT_YET_RECRUITING
Conditions: Primary Sjögren Syndrome
Interventions: DRUG: 68Ga-P16-093
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-terms Effects of Simulation-based Ultrasound Training: A Randomized Trial
Status: COMPLETED
Conditions: Ultrasound Training|Ultrasound Simulation|Ultrasound Assessment|Technology-enhanced Learning|Virtual Reality Simulation
Interventions: OTHER: Simulation-based ultrasound training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Retention of Peek and Bre.Flex Materials Maxillary Bilateral Bounded Removable Partial Dentures
Status: UNKNOWN
Conditions: Retention
Interventions: OTHER: PEEK|OTHER: Bre.flex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Vapor Ablation for Localized Cancer Lesions of the Lung (VAPORIZE)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Metastatic Lung Cancer|Lung Cancer
Interventions: DEVICE: Bronchoscopic Thermal Vapor Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy and Toxicity of Pamiparib Combined With Tamoxifen in the Treatment of Epithelial Ovarian Cancer Patients With Biochemical Recurrence During First-line PARPi Maintenance Therapy
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Pamiparib/Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of HFNC as an Alternative to CPAP Therapy in Surgical Patients With Suspected Moderate to Severe OSA
Status: COMPLETED
Conditions: OSA
Interventions: DEVICE: CPAP face mask|DEVICE: High flow nasal cannula (HFNC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Combination Treatment With Avonex and Zocor in Relapsing Remitting Multiple Sclerosis
Status: UNKNOWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events
Status: RECRUITING
Conditions: Multivessel Coronary Artery Disease|Ischemia|Vulnerable Plaque|Coronary Artery Disease
Interventions: PROCEDURE: PCI revascularization strategy based on combined FFR and OCT assessment|PROCEDURE: PCI revascularization strategy based FFR assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary intervention|PROCEDURE: coronary artery bypass graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With High-Dose Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sustained Neutral Apophyseal Glides Half Rotation Technique and Gong's Mobilizations in Cervicogenic Headache
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: OTHER: Sustained neutral apophyseal glides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maraviroc Immune Recovery Study
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: maraviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Broccoli In Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Sulforaphane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluocinolone Acetonide Implant Compared to Sham Injection in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: fluocinolone acetonide|DRUG: Fluocinolone Acetonide|PROCEDURE: Standard of care laser photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing IBI362 vs Semaglutide in Chinese Adults With Early Type 2 Diabetes and Obesity
Status: RECRUITING
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: IBI362|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)
Status: RECRUITING
Conditions: Ewing Sarcoma
Interventions: DRUG: Naxitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Histological Characteristics of Serrated Lesions of the Colon
Status: ACTIVE_NOT_RECRUITING
Conditions: Colonic Neoplasms|Colorectal Cancer|Sessile Serrated Adenoma|Polyp of Colon
Interventions: PROCEDURE: Colonoscopy|PROCEDURE: Polypectomy or biopsy|GENETIC: Molecular analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IIaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: Ilaprazole|DRUG: omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Two-Year Intensive Reading Intervention for Middle School English Learners With Reading Difficulties
Status: UNKNOWN
Conditions: Learning Disorders|Dyslexia
Interventions: BEHAVIORAL: RISE Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Response Prediction to Neoadjuvant Chemoradiation in Esophageal Cancer Using Artificial Intelligence & Machine Learning
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Neoplasm
Interventions: RADIATION: Neo-Adjuvant Radiotherapy|DRUG: Neo-Adjuvant Chemotherapy|PROCEDURE: Esophagectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Trial of Inactivated West Nile Virus Vaccine
Status: COMPLETED
Conditions: West Nile Viral Infection
Interventions: BIOLOGICAL: HydroVax-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Treatment A: BGF MDI HFA|DRUG: Treatment B: BGF MDI HFO|DRUG: Treatment C: BGF MDI HFO|DEVICE: AeroChamber Plus Flow-Vu spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Solid State vs. Balloon Esophageal Catheter for Estimation of Pleural Pressure
Status: COMPLETED
Conditions: Respiratory Failure|Mechanical Ventilation
Interventions: DEVICE: intelligent Esophageal Pressure Catheter (iEPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)
Status: RECRUITING
Conditions: ACL|Opioid Use|Cryotherapy Effect|Vibration; Exposure|Pain, Postoperative
Interventions: DEVICE: VibraCool mechanical stimulation and neuromodulatory therapeutic device|DEVICE: Cryocompression (Game Ready, Bregs) device|DEVICE: Standard ice packs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Adolescent Contraception
Status: COMPLETED
Conditions: Pregnancy Related|Contraception|Contraceptive Usage|Contraception Behavior|Pregnancy
Interventions: BEHAVIORAL: SexHealth II|DRUG: Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Graft Reconditioning With Hypothermic Machine Perfusion on HCC Recurrence After Liver Transplantation
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Transplant; Complications
Interventions: DEVICE: D-HOPE machine perfusion|PROCEDURE: Liver transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Window of Opportunity Trial of Durvalumab (MEDI4736) or Durvalumab/Tremelimumab as Neoadjuvant Chemotherapy to Identify Immune Dynamics in Surgically Resectable Head and Neck Cancer Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II-IVB Operable HNSCC Oral Cavity|Hypopharynx|Oropharynx|Larynx
Interventions: DRUG: Durvalumab|DRUG: durvalumab + tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiniTightRope Suspensionplasty Compared With LRTI for the Treatment of Basilar Thumb Arthritis
Status: TERMINATED
Conditions: Arthritis|Joint Diseases
Interventions: PROCEDURE: Ligament reconstruction tendon interposition|PROCEDURE: Suspensionplasty with one-suture construct|PROCEDURE: Suspensionplasty with two-suture construct
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who Are Current Cigarette Smokers
Status: COMPLETED
Conditions: Healthy|Cigarette Smoking
Interventions: BIOLOGICAL: 20K EU CCRE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Study to Assess Dose-response Relationship of HCP1803 in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: HCP1803|DRUG: Amlodipine|DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Ventilation Bundle in Postoperative Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: OTHER: Early application of NIV|DEVICE: Fiberoptic bronchoscopy|DRUG: Propofol|OTHER: Conventional application of NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma
Status: RECRUITING
Conditions: IDH1 wt Allele|Recurrent Anaplastic Astrocytoma|Recurrent Glioblastoma|Recurrent Gliosarcoma|Recurrent Malignant Glioma
Interventions: BIOLOGICAL: Oncolytic Adenovirus Ad5-DNX-2401|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Effects of Kinesio Taping on Knee Joint Proprioception and Spatiotemporal Gait Parameters in Patient With Chrondromalacia Patellae
Status: ACTIVE_NOT_RECRUITING
Conditions: Chondromalacia
Interventions: DIAGNOSTIC_TEST: Conventional physical therapy|OTHER: Kinesiotaping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Probiotic Strains on Bone Mineral Density in Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis, Postmenopausal|Bone Density, Low
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperfine Portable MRI in Hydrocephalus and Other Conditions Prompting Outpatient Brain Imaging
Status: RECRUITING
Conditions: Hydrocephalus|Neurological Disorder
Interventions: DEVICE: Hyperfine MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Omentopexy and Clips on the Staple Line During Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Compassion|Bleeding|Nausea, Postoperative|Readmission
Interventions: PROCEDURE: Omentopexy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Visual Rehabilitation in Children With Homonymous Hemianopia: a Pilot Study on Virtual-reality Stimulation
Status: COMPLETED
Conditions: Hemianopia|Brain Tumor|Children, Only
Interventions: DEVICE: Immersive Virtual-Reality Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound Dehiscence
Status: UNKNOWN
Conditions: Fibrolipoma of Filum Terminale|Lipomyelomeningocele|Split Cord Malformation|Dermal Sinus|Tethered Cord Syndrome|Tumor
Interventions: DRUG: Acetazolamide|OTHER: prone positioning|OTHER: Acetazolamide+ prone positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endovascular Denervation (EDN) for the Treatment of Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus (T2DM)
Interventions: DEVICE: Endovascular Denervation System (Netrod)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment
Status: RECRUITING
Conditions: Substance-Related Disorders|Treatment Adherence
Interventions: BEHAVIORAL: Motivational Interviewing at Intake (MII)|BEHAVIORAL: Intake as Usual (IAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Interventions: DRUG: Bosutinib|DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis|DRUG: Nilotinib|DRUG: Ruxolitinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Conventional Exercise and Tai Chi Exercise on College Students
Status: COMPLETED
Conditions: Internet Addiction|Exercise|Tai Chi|Randomized Clinical Trial
Interventions: BEHAVIORAL: Conventional Exercise and Tai Chi Exercise interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Quetiapine fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: CAR.B7-H3|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes
Status: COMPLETED
Conditions: Aphasia|Stroke|Dyslexia, Acquired
Interventions: BEHAVIORAL: One-on-one treatment of reading difficulties
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of an Online Hearing Support for First-time Hearing Aid Users
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Hearing Impairment|Hearing Disorders|Hearing Disability|Ear Diseases|Sensation Disorders|Otorhinolaryngologic Diseases
Interventions: BEHAVIORAL: Online hearing support for first-time hearing aid users|BEHAVIORAL: Hearing rehabilitation according to common practice.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: CR845|DRUG: Placebo|DRUG: CR845|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial of the Implantation of Mouse Renal Adenocarcinoma Macrobeads in Subjects With Castration-Resistant Prostate Cancer Resistant to Taxanes (Docetaxel, Cabazitaxel) and Evidence of Disease Progression on Androgen-axis Inhibition and/or Immunotherapy in the Form of Sipuleucel-T
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Cancer Macrobead placement in abdominal cavity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Harmonic Scalpel to Conventional Diathermy in Perforator Flap Elevation for Head and Neck Reconstruction
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: Diathermy|PROCEDURE: Harmonic Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine PF-07220060 Together With Letrozole Compared to Letrozole Alone in Women Post Menopause
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: PF-07220060|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: LTC004+Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigicon Infla10® Three-Piece Inflatable Penile Prosthesis (ERASE ED)
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: DEVICE: Rigicon Infla 10® Three-Piece Inflatable Penile Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of EUS-PCA in IPMN Pancreatic Cysts
Status: NOT_YET_RECRUITING
Conditions: Intraductal Papillary Mucinous Neoplasm of Pancreas
Interventions: PROCEDURE: Endoscopic ultrasound-guided pancreatic cyst chemoablation (EUS-PCA) using gemcitabine and paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Study of AZD4547 in Patients With FGFR1 or FGFR2 Amplified Tumours
Status: UNKNOWN
Conditions: Gastric Cancer|Oesophageal Cancer|Breast Cancer|Squamous Cell Carcinoma of the Lung
Interventions: DRUG: AZD 4547
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic Treatments
Status: RECRUITING
Conditions: Cirrhosis|Diabetes Mellitus|Oncologic Disorders
Interventions: DRUG: Esmolol Injection [Brevibloc]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Telephone Follow-up in Patient's Health-related Quality of Life That Use Warfarin
Status: COMPLETED
Conditions: Quality of Life|Warfarin|Health Education|Patient Compliance
Interventions: BEHAVIORAL: Educational Program|BEHAVIORAL: Telephone follow-up|BEHAVIORAL: Face to face counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Self-Management and Glycemic Control in Adult Haitian Immigrants With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Patient Engagement|Patient Education
Interventions: BEHAVIORAL: Diabetes Self-Management Behaviors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled AZD4604 in Healthy Japanese and Chinese Participants.
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: AZD4604|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotics Continuous Infusion at Home
Status: UNKNOWN
Conditions: Severe Bacterial Infections
Interventions: DRUG: Cefepime|DRUG: Piperacillin/tazobactam|DRUG: Meropenem|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment
Status: UNKNOWN
Conditions: Melanoma|Non Small Cell Lung Cancer|Small Cell Lung Cancer
Interventions: PROCEDURE: Blood sample|PROCEDURE: Tumorous biopsy|PROCEDURE: Healthy material sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: intravenous (IV) arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atraumatic Restorative Treatment Sealants in First Permanent Molars
Status: COMPLETED
Conditions: Caries, Dental
Interventions: PROCEDURE: Glass ionomer sealant|BEHAVIORAL: Non-sealant (toothbrushing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigation and Validation of a Study Project on Digital Therapy Management of Patients With Arterial Hypertension
Status: RECRUITING
Conditions: Cardiovascular Diseases|Hypertension
Interventions: DEVICE: Hypertension therapy through iATROS medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin-(1-7) in Peripheral Arterial Disease
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Angiotensin 1-7|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning and Contrast Induced - Acute Kidney Injury in Patients Undergoing Elective PCI
Status: COMPLETED
Conditions: Remote Ischemic Preconditioning|Contrast Induced - Acute Kidney Injury
Interventions: PROCEDURE: Remote Ischemic Preconditioning|PROCEDURE: Sham Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Blood Flow Restriction Therapy Following ACL Tear
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Tear|Knee Injuries|Sport Injury
Interventions: DEVICE: Blood flood restriction cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose-dependent Insulinotropic Polypeptide - New Role as Blood Glucose Stabilizer?
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: glucose-dependent insulinotropic polypeptide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: GLP-1-mediated Gluco-metabolic Effects of Bile Acid Sequestration
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sevelamer|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Toxicity, Drug
Interventions: PROCEDURE: neoadjuvant chemoradiotherapy combined with Camrelizumab and Nimotuzumab followed by surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Sildenafil Citrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess VB-201 in Patients With Psoriasis
Status: COMPLETED
Conditions: Active Plaque Psoriasis
Interventions: DRUG: VB-201|DRUG: VB-201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Function After Obstetric Injury to the Anal Sphincter
Status: ENROLLING_BY_INVITATION
Conditions: Obstetric Anal Sphincter Injury|Anal Incontinence|Urinary Incontinence|Sexual Dysfunction
Interventions: OTHER: Obstetric Anal Sphincter Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extracorporeal Photopheresis in Liver Transplantation. Phase II Clinical Trial in Safety and Efficacy in Patients With Gradual Decrease of Immunosuppression.
Status: COMPLETED
Conditions: Liver Transplantation|Immunosuppression
Interventions: PROCEDURE: Extracorporeal Photopheresis Procedure (FEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: DE-101 Ophthalmic Suspension|DRUG: DE-101 Ophthalmic Suspension|DRUG: DE-101 Ophthalmic Suspension Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intercostal Liposomal Bupivacaine for the Management of Blunt Chest Wall Trauma
Status: COMPLETED
Conditions: Blunt Chest Wall Trauma|Rib Fracture|Sternal Fracture
Interventions: DRUG: Liposomal bupivacaine|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT