pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb
Status: RECRUITING
Conditions: Spinal Muscular Atrophy|Spinal Muscular Atrophy Type 3|Spinal Muscular Atrophy Type II|Spinal Muscular Atrophy 4|SMA
Interventions: DEVICE: Spinal Cord Stimulator (Octopolar Medtronic Vectris Leads)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pregabalin Versus Pulsed Radiofrequency Ablation for Treatment of Chronic Post-thoracotomy Pain
Status: COMPLETED
Conditions: Chronic Post-thoracotomy Pain
Interventions: DRUG: lyrica, vronogabic (pregabalin)|PROCEDURE: pulsed radiofrequency ablation of the dorsal root ganglion under fluroscopic guidance/ radiofrequency neurolysis/ radiofrequency denervation device name: Neuro Therm TM 1100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate a Pharmacodynamics Between S-pantoprazole 10, 20, 40mg and Pantoprazole 20, 40mg in Healthy Male Subjects
Status: UNKNOWN
Conditions: Healthy Male Subjects
Interventions: DRUG: AGSPT_10|DRUG: AGSPT_20|DRUG: AGSPT_40|DRUG: Pantoprazole_20|DRUG: Pantoprazole_40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perinatal Mental Health Care in Switzerland
Status: UNKNOWN
Conditions: Mental Disorder|Perinatal|Depression|Anxiety Disorders|Panic Disorder|Post Traumatic Stress Disorder|Adaptation Reaction|Behavior Disorders|Substance Abuse|Psychosis|Health Care Seeking Behavior|Health Care Utilization|Health Care Acceptability
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modifying Metabolic Syndrome and Cardiovascular Risk for Prostate Cancer Patients on ADT Using a Risk Factor Modification Program and Continuous Fitbit Monitoring
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: BEHAVIORAL: Educational Intervention|BEHAVIORAL: Exercise Intervention|DEVICE: FitBit|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of Magnesium Isoglycyrrhizinate in the Prevention of Chemotherapy Related Acute Liver Injury
Status: UNKNOWN
Conditions: Neoplasms|Liver Injury
Interventions: DRUG: Magnesium Isoglycyrrhizinate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Meditoxin® Injection for Cervical Dystonia in Adults With Cerebral Palsy
Status: COMPLETED
Conditions: Adult Cerebral Palsy
Interventions: DRUG: Meditoxin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) for the Treatment of Tinnitus
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DEVICE: BrainSTIM Transcranial Stimulator|DEVICE: BrainSTIM Transcranial Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively
Status: COMPLETED
Conditions: Abdominal Cancer
Interventions: DRUG: transversus abdominis-plane block with local anesthetic 20 ml of bupivacaine 0.5% + 10 mg morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Melphalan|DRUG: Thiotepa|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
Status: COMPLETED
Conditions: Nerve Block, Nephrectomy, Analgesia
Interventions: PROCEDURE: preoperative single-shot TMQLB|PROCEDURE: preoperative single-shot TPVB|DRUG: patient controlled intravenous analgesia(PCIA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Progressive Resistance Training of the Biceps in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: therapeutic exercises|OTHER: biceps resistance training and therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients
Status: TERMINATED
Conditions: Oral Mucositis
Interventions: DEVICE: Gelclair|COMBINATION_PRODUCT: First® Mouthwash BLM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ARISTOCRAT-A Randomized Controlled Trial Evaluating Closure Following Access With the AXERA (Device Name) 2 Access System
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Vascular Access Device|PROCEDURE: Standard Manual Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study
Status: RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Ephedrine|DRUG: Phenylephrine|DRUG: Norepinephrine|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The International Diabetes Closed Loop (iDCL) Trial: Protocol 4
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: interoperable Artificial Pancreas System (iAPS)|OTHER: Sensor-Augmented Pump (SAP)/Predictive Low Glucose Suspend (PLGS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DEVICE: heparin-induced extracorporeal LDL precipitation|DEVICE: dextran sulfate adsorption
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dibenzyl Trisulphide (GUINEAHEN WEED) for Stage IV Cancer
Status: UNKNOWN
Conditions: Stage IV Prostate Cancer|Stage IV Colon Cancer|Stage IV Breast Cancer|Stage IV Cancer of the Cervix
Interventions: DRUG: Dibenzyl trisulphide capsules|DRUG: Dibenzyl trisulphide capsules|DRUG: Dibenzyl trisulphide capsules|DRUG: Dibenzyl trisulphide capsules|DRUG: Stage IV Breast Cancer Placebo|DRUG: Stage IV: Colon Cancer Placebo|DRUG: Cervical Cancer Stage IV Placebo|DRUG: Cancer of the Prostate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COLchicine On-admission to Reduce Inflammation in Acute Coronary Syndrome (COLOR-ACS)
Status: COMPLETED
Conditions: Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: Colchicine|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of the Use of the MAURISSE Application in People Suffering From an Addiction.
Status: RECRUITING
Conditions: Substance Related Disorder|Personality Disorders
Interventions: OTHER: The MAURISSE application use|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Lehfilcon A contact lenses|DEVICE: Multipurpose disinfection solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Suramin in Subjects With Furosemide-Resistant AKI
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Kidney Injury
Interventions: DRUG: Suramin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)
Status: COMPLETED
Conditions: Glucose Metabolism Disorders
Interventions: OTHER: GIP-A|OTHER: Placebo|OTHER: GLP-1 receptor antagonist Exendin[9-39]|OTHER: GIP-A + Exendin[9-39]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Controlled Human Plasmodium Vivax Infection
Status: COMPLETED
Conditions: Malaria, Vivax
Interventions: OTHER: Plasmodium vivax infection|PROCEDURE: Collection of 250mL blood from each volunteer (N=2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Cycloserine|DRUG: Ethionamide|DRUG: Capreomycin sulfate|DRUG: Aminosalicylic acid|DRUG: Streptomycin sulfate|DRUG: Ethambutol hydrochloride|DRUG: Amikacin sulfate|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Pyridoxine hydrochloride|DRUG: Levofloxacin|DRUG: Rifampin|DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Investigation Of The Effects Of ClearLift Q-Switched Nd:Yag 1064nm Laser Module In The Treatment Of Facial Skin Wrinkles
Status: NOT_YET_RECRUITING
Conditions: Facial Skin Wrinkles
Interventions: DEVICE: Alma Harmony
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1, TAK-648, Single-Rising Dose Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-648|DRUG: TAK-648 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Macronutrient Composition
Status: COMPLETED
Conditions: Metabolic Syndrome|Non-alcoholic Fatty Liver Disease|Obesity
Interventions: OTHER: Low-fat diet|OTHER: Low-carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of Acellbia® (JSC "BIOCAD") With Methotrexate in First Line Biological Therapy of Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Acellbia|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobilized Psychoeducation and Skills Based Intervention (Pep-Pal) for Caregivers of Patients With Advanced Illness
Status: COMPLETED
Conditions: Distress|Anxiety|Depression
Interventions: BEHAVIORAL: Pep-Pal|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-Invasive Brain Stimulation and Delirium
Status: WITHDRAWN
Conditions: Mental Disorders|Delirium
Interventions: DEVICE: rTMS/iTBS/tACS|DEVICE: Sham TMS/tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Immediate Effect of Mobilisation With Movement in Amateur Futsal Athletes With Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Injuries and Disorders
Interventions: PROCEDURE: Mobilisation With Movement 1|PROCEDURE: Mobilisation With Movement 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Of Ibuprofen 50mg/ml (laboratórios Pfizer Ltda) In The Oral Suspension Form.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alivium®|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps
Status: ACTIVE_NOT_RECRUITING
Conditions: Sinusitis|Nasal Polyps|Polyps
Interventions: DRUG: 611|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of BIBR 963 ZW After 50 mg of BIBR 1048 MS With and Without of Pantoprazole in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS Capsule A|DRUG: BIBR 1048 MS Capsule B|DRUG: BIBR 1048 MS Capsule C|DRUG: BIBR 1048 MS Capsule D|DRUG: BIBR 1048 MS tartaric acid solution|DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Status: RECRUITING
Conditions: Chronic Heart Failure|Iron Deficiency, Latent
Interventions: DRUG: Ferinject|OTHER: Diet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study of Short and Long-term Use of Protopic Ointment in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Protopic|DRUG: Corticosteroid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cariprazine for Mania
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Treatment-Resistant Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder|Bipolar Depression|Bipolar I Disorder|Bipolar II Disorder
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Midazolam Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability and Pharmacokinetics of Calcium Dobesilate (Doxium®) in the Nasal Mucosal Tissue, Saliva and Blood of Treated Patients
Status: UNKNOWN
Conditions: Biological Availability
Interventions: DRUG: Calcium Dobesilate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prulifloxacin in Chronic Bacterial Prostatitis (CBP)
Status: COMPLETED
Conditions: Chronic Bacterial Prostatitis
Interventions: DRUG: Prulifloxacin 600 mg|DRUG: Levofloxacin 500mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Study of Levitra to Treat Men With Erections Problems and Previously Untreated With Similar Therapy.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Taenia Solium Elimination Versus Control: What is the Best Way Forward for Sub-Saharan Africa?
Status: COMPLETED
Conditions: Taenia Solium Infection
Interventions: DRUG: Mass drug administration, praziquantel 10mg/kg|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Optimizing Linkage and Retention to Hypertension Care in Rural Kenya
Status: COMPLETED
Conditions: Hypertension|High Blood Pressure
Interventions: BEHAVIORAL: behavioral communication strategy|BEHAVIORAL: Behavioral communication strategy, plus smartphone-based tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1-2, XIAP Antisense AEG35156 With Gemcitabine in Patients With Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Carcinoma|Pancreas
Interventions: DRUG: AEG35156
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing 3 and 4 Week Regimen of Gemcitabine and Cisplatin in Patients With Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Therapy for Ulcerative Colitis (UC)
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: amoxicillin, metronidazole and doxycycline|DRUG: amoxicillin and doxycyclin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendicectomy
Status: COMPLETED
Conditions: Children|Appendicitis
Interventions: PROCEDURE: QLB|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter RCT of ADV-TK Gene Therapy Improving the Outcome of Liver Transplantation for Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ADV-Tk|PROCEDURE: LT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery Revascularization in Diabetes
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary intervention (PCI)|PROCEDURE: Coronary artery bypass graft (CABG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Clock Genes
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy for Malignant Dysphagia in Patients With Advanced Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Adenocarcinoma
Interventions: PROCEDURE: Cryotherapy|PROCEDURE: Esophagogastroduodenoscopy (EGD)|PROCEDURE: Endoscopic ultrasound (EUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Core Strengthening for DRA in Postpartum Women
Status: COMPLETED
Conditions: Diastasis Recti|Postpartum|Low Back Pain
Interventions: OTHER: Core Muscle Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MGC018 With or Without MGA012 in Advanced Solid Tumors
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Head and Neck|Triple Negative Breast Cancer|Melanoma|Advanced Solid Tumor, Adult|Metastatic Castrate Resistant Prostate Cancer|Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: vobramitamab duocarmazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: CROS|DEVICE: Hearing Aid|OTHER: Cochlear Implant Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Use For Admission Blood Tests of Very Low Birth Weight Preterm Neonates: A Multi-center Randomized Clinical Trial
Status: COMPLETED
Conditions: Anemia
Interventions: PROCEDURE: Drawing admission labs from cord blood|PROCEDURE: Drawing admission labs from infant blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Musical Intervention on Patient Pain and Anxiety for Office-based Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: PROCEDURE: Office-based procedure indicated for chronic pain with music|PROCEDURE: Office-based procedure indicated for chronic pain without music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled Corticosteroids on Vocal Fold Nodules in Children
Status: RECRUITING
Conditions: Vocal Fold Nodules
Interventions: DRUG: Fluticasone propionate|BEHAVIORAL: Standard voice therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TAC-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Routine Nebulization of Mucolytics and Bronchodilators During Mechanical Ventilation
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: acetylcysteine and salbutamol|DRUG: acetylcysteine|DRUG: salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline for the Symptomatic Treatment of Fatigue in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microbial Colonization of Dairy Free Oral Probiotics
Status: UNKNOWN
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: Streptococcus salivarius M18 lozenges|DIETARY_SUPPLEMENT: Streptococcus salivarius M18 dairy free lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Aripiprazole in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Aripiprazole+ ADT|DRUG: Placebo+ ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Comparing TVT SECUR System and Trans Vaginal Obturator Tape for Surgical Management of Stress Urinary Incontinence
Status: TERMINATED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: transvaginal obturator tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Prevention Program and Therapeutic Patient Education Program of Patients With Uncontrolled Epilepsy
Status: RECRUITING
Conditions: Epilepsy
Interventions: PROCEDURE: Risk prevention session|PROCEDURE: Usual Therapeutic Patient Education (TPE) management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Predictors of Antidepressant Response
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Placebo, identified as placebo to participants|DRUG: Celexa or other antidepressant as clinically indicated|OTHER: Placebo, identifed to participants as "Active medication"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Trial to Assess the Safety and Activity of Nexagon® for the Treatment of Venous Leg Ulcers (The NOVEL Study)
Status: COMPLETED
Conditions: Venous Ulcer
Interventions: DRUG: Nexagon®|DRUG: Nexagon® vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Midazolam Versus Intravenous Diazepam for Acute Seizure in Children
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Intra muscular Midazolam|DRUG: Intravascular Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea|Pregnancy|Obesity|Preeclampsia|Sleep
Interventions: DEVICE: Positive Airway Pressure|OTHER: Nasal Dilator Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Oral Curcumin Supplementation in Dry Age-related Macular Degeneration (AMD) Patients
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Longvida curcumin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Feasibility of a Mindfulness Booster Course for Healthcare Staff Who Attended an 8-week Mindfulness Course
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Mindfulness Booster Course|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain
Status: NOT_YET_RECRUITING
Conditions: Pain, Nerve
Interventions: DEVICE: Active Treatment|DEVICE: Non-active Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Humalog|DRUG: Novolog|DRUG: BC222 insulin lispro|DEVICE: Bionic Pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation Effect of Blood Transfusion
Status: COMPLETED
Conditions: Incompatible Blood Transfusion|Immune Defect|Surgery
Interventions: BIOLOGICAL: No blood transfusion|BIOLOGICAL: Day 0 blood transfusion|BIOLOGICAL: Day 1 or 2 blood transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product
Status: COMPLETED
Conditions: Mental Health Disorder|Obesity|Overweight
Interventions: BEHAVIORAL: Vira mobile app intervention|BEHAVIORAL: Vira mobile app intervention + coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HAIC Combined With Tislelizumab and Apatinib for Unresectable Intrahepatic Cholangiocarcinoma
Status: UNKNOWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: HAIC Combined with Tislelizumab and Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?
Status: COMPLETED
Conditions: Needlestick Injuries
Interventions: PROCEDURE: Lidocaine injection with bicarbonate|PROCEDURE: lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency
Status: TERMINATED
Conditions: Renal Insufficiency|Heart Failure
Interventions: DRUG: Tonapofylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of U/S Retrolaminar Block and Erector Spinae Plane Block in MRM
Status: COMPLETED
Conditions: Breast Neoplasms|Analgesia
Interventions: PROCEDURE: The Ultrasound-guided Retrolaminar Block Group|PROCEDURE: The Ultrasound-guided Erector Spinae Plane Block Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Esthetics Around Immediate Implants in VIP - CT Grafted vs Non-grafted Sites.RCT
Status: COMPLETED
Conditions: Buccal Bone Loss in Immediate Implants
Interventions: PROCEDURE: VIP graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of GSK Biologicals' HBV-MPL Vaccine and Engerix™-B in Healthy Adults (15-40 Yrs).
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBV-MPL vaccine 208129|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia
Status: COMPLETED
Conditions: Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: cytarabine|DRUG: mitoxantrone hydrochloride|DRUG: alvocidib|OTHER: pharmacological study|OTHER: laboratory procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Lobradimil|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity on Prescription in Patients With Metabolic Risk Factors.
Status: COMPLETED
Conditions: Health Behavior|Activities of Daily Living|Metabolic Syndrome X|Quality of Life
Interventions: BEHAVIORAL: PAP-treatment by physiotherapist|BEHAVIORAL: Ordinary PAP-treatment at the health care center
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Safety, Tolerability, and Pharmacokinetics Study of PF-04805712 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04805712
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
Status: UNKNOWN
Conditions: Distal Humerus Fracture|Distal Femur Fracture|Distal Tibia Fracture|Proximal Humeral Fracture
Interventions: OTHER: 3D printed (3DP) bone models + CT imaging|OTHER: CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Transcranial Direct Current Stimulation (tDCS) in the Treatment of Adult Attention Deficit Disorder (ADD).
Status: UNKNOWN
Conditions: Adult Attention Deficit Disorder
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Plus R-CHOP as the First-line Treatment in Patients With Diffuse Large B-Cell Lymphoma.
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma|Sintilimab|TP53 Mutation
Interventions: DRUG: Sintilimab-R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Providing Resources to Enhance African American Patients' Readiness to Make Decisions About Kidney Disease (PREPARED) Study
Status: COMPLETED
Conditions: End Stage Renal Disease (ESRD)|Chronic Kidney Disease (CKD)
Interventions: BEHAVIORAL: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain
Status: COMPLETED
Conditions: Herpes Zoster|Neuralgia|Pain|HIV Infections|Peripheral Nervous System Diseases|Diabetic Neuropathies|Diabetes Mellitus|Polyneuropathies
Interventions: DRUG: Capsaicin Dermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: High flow oxygen through nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of Extra Virgin Olive Oil on Postprandial Blood Glucose in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive Oil (EVOO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography
Status: TERMINATED
Conditions: High Altitude Pulmonary Edema
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mast Cells in Male Pelvic Pain and and Lower Urinary Tract Dysfunction
Status: COMPLETED
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: DRUG: Cromolyn Sodium|DRUG: Cetirizine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Combination Therapy With Docetaxel-oxaliplatin-capecitabine in Patients With Advanced Gastric Adenocarcinoma and Intermediate General Status
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: DOX: Docetaxel, oxaliplatin, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Model-based Sensory Stimulation Intervention on Preventing Delirium Among Intensive Care Unit Patients: A Randomised Controlled Trial
Status: COMPLETED
Conditions: Delirium, Intensive Care Unit, Randomised Controlled Trial
Interventions: OTHER: Sensory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder: Proof of Concept
Status: WITHDRAWN
Conditions: Insomnia Chronic|Posttraumatic Stress Disorder
Interventions: DRUG: Pimavanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Lactobacillus Crispatus M247, LSIL and Microbiota"
Status: RECRUITING
Conditions: Vaginal Flora Imbalance|ASC-US|LSIL|HPV Infection
Interventions: DRUG: Lactobacillus Crispatus M247
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-assisted Versus Real-time Ultrasound-guided Combined Spinal-epidural Anesthesia in Elderly Patients
Status: RECRUITING
Conditions: Ultrasound Therapy; Complications
Interventions: PROCEDURE: Ultrasound-assisted localization, US-AS|PROCEDURE: Real-time ultrasound guidance, US-RTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Efficacy and Safety of Tacrolimus Capsules With Leflunomide Tablets in Lupus Nephritis Patients
Status: TERMINATED
Conditions: Lupus Nephritis
Interventions: DRUG: tacrolimus capsule|DRUG: tacrolimus placebo|DRUG: leflunomide tablet|DRUG: leflunomide placebo|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fluid Therapy on Microcirculatory Reactivity
Status: UNKNOWN
Conditions: Microcirculation|Fluid Therapy
Interventions: OTHER: crystal therapy|OTHER: colloid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Mobile Application to Promote Self-management and Improve Outcomes in Heart Failure
Status: TERMINATED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Sodium intervention|BEHAVIORAL: Clinical worsening intervention|BEHAVIORAL: Educational content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NY-ESO-1 Vaccine in Combination With Ipilimumab in Patients With Unresectable or Metastatic Melanoma
Status: TERMINATED
Conditions: Unresectable or Metastatic Melanoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: NY-ESO-1 Protein Vaccine|BIOLOGICAL: NY-ESO-1 OLP4 Vaccine with Poly-ICLC and Montanide|BIOLOGICAL: NY-ESO-1 OLP4 Vaccine with Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Kinesio Taping on Biomechanical and Clinical Outcomes in Runners With Iliotibial Band Friction Syndrome
Status: RECRUITING
Conditions: Iliotibial Band Syndrome
Interventions: DEVICE: Kinesio Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Patients With SCLC of Veliparib in Combination With Topotecan
Status: UNKNOWN
Conditions: Small Cell Lung Cancer SCLC
Interventions: DRUG: veliparib|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure
Status: TERMINATED
Conditions: Heart Failure
Interventions: PROCEDURE: Subcutaneous adipose tissue collection|DIAGNOSTIC_TEST: Peripheral arterial tonometry (PAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pyrotinib Plus Capecitabine for Adjuvant Treatment of HER2 Positive Early-stage Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Breast Cancer|Early-stage Breast Cancer
Interventions: DRUG: pyrotinib combined with Capecitabine|DRUG: treatment of physician's choice
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Healthy Elementary School of the Future
Status: COMPLETED
Conditions: Overweight|Physical Activity|Malnutrition|Child Development|Lifestyle-related Condition|Socioeconomic Difficulty
Interventions: OTHER: The Healthy Primary School of the Future|BEHAVIORAL: The Physical Activity School
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
Status: COMPLETED
Conditions: Chest Pain|Sickle Cell Anemia
Interventions: DRUG: Nitric Oxide|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patient Satisfaction and Shade Matching of Vita Suprinity Versus Lithium Disilicate (E-max) Ceramic Crowns in Esthetic Zone
Status: UNKNOWN
Conditions: Personal Satisfaction
Interventions: OTHER: Prosthetic crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scalpel Versus Laser Gingivectomy in Orthodontic Patients in the Management of Periodontal Health
Status: COMPLETED
Conditions: Orthodontic Appliance Complication|Gingival Overgrowth
Interventions: PROCEDURE: Scalpel Gingivectomy|PROCEDURE: Laser Gingivectomy|PROCEDURE: Nonsurgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections
Status: UNKNOWN
Conditions: Malaria,Falciparum
Interventions: DRUG: Pyronaridine tetraphosphate 180mg:artesunate 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Femtosecond Laser in Residency Training (FLIRT) Pilot Study
Status: WITHDRAWN
Conditions: Cataract|Intraocular Lens Implantation
Interventions: PROCEDURE: FLA-CEIOL|PROCEDURE: CEIOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fondaparinux (Arixtra) With Chemotherapy for Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Venous Thromboembolism
Interventions: DRUG: Combination of Arixtra with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Novartis Meningococcal B Vaccine When Administered to Immunocompromised Children and Adolescents Compared to Healthy Subjects.
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: rMenB+OMV|BIOLOGICAL: rMenB+OMV|BIOLOGICAL: rMenB+OMV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation
Status: COMPLETED
Conditions: Chronic Spinal Cord Injury|Neurogenic Bladder
Interventions: DEVICE: High Dose|DEVICE: Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT