pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Arthroplasty, Total
Interventions: DRUG: Enoxaparin|DRUG: KN060 Low|DRUG: KN060 Middle|DRUG: KN060 Hight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of a New Sublingual and a Reference Alprazolam Immediate Release Tablet Formulation
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: alprazolam commercial immediate release oral tablet|DRUG: alprazolam test sublingual tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intestinal Microbiome and Extremes of Atherosclerosis
Status: COMPLETED
Conditions: Gastrointestinal Microbiome, Atherosclerosis, Nutrients|Renal Function
Interventions: DIAGNOSTIC_TEST: Plasma levels of metabolites|BEHAVIORAL: Dietary questionnaire|DIAGNOSTIC_TEST: Intestinal microbiome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof of Concept Study Evaluating RNS60 in the Treatment of Relapsing Remitting Multiple Sclerosis
Status: WITHDRAWN
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: RNS60 125 ml|DRUG: RNS60 250 ml|DRUG: Interferon beta 1a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DIETARY_SUPPLEMENT: CITICOLINE|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Robotic Rehabilitation And Vagus Nerve Stimulation In Ischemia Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Vagus Nerve Stimulation|Robotic Rehabilitation|Autonomic Nervous System
Interventions: DEVICE: Robotic Rehabilitation|DEVICE: Transcutaneous Auricular Vagal Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Tibial Nerve Block vs. Local Corticosteroid Injection in Recalcitrant Plantar Fasciitis Treatment
Status: UNKNOWN
Conditions: Plantar Fascitis|Tibial Nerve|Injections|Ultrasonography
Interventions: DEVICE: Injection|DEVICE: Tibial nerve block|OTHER: Conservational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
Status: RECRUITING
Conditions: Systemic Inflammatory Response Syndrome|Infections|Thoracic Aortic Aneurysm|Aortic Diseases|Immunological Abnormality
Interventions: DIAGNOSTIC_TEST: Blood sample test|PROCEDURE: Thoracic Aortic Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging
Status: COMPLETED
Conditions: Myocardial Ischemia|Myocardial Viability|Coronary Stenosis|Vulnerable Coronary Plaques
Interventions: DIAGNOSTIC_TEST: 128 Multislice CT coronary angiography|DIAGNOSTIC_TEST: 2D Cardiac Transthoracic Echocardiography|DIAGNOSTIC_TEST: Laboratory Blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exemestane With or Without Bicalutamide in Treating Patients With Stage IV Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Exemestane|DRUG: Exemestane+bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment
Status: RECRUITING
Conditions: Head and Neck Cancer|Hypoxia|Magnetic Resonance Imaging|Cancer Neck
Interventions: DIAGNOSTIC_TEST: [18F]MISO-PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Muscle Derived Cells for Treatment of Tongue Dysphagia
Status: RECRUITING
Conditions: Oropharyngeal Dysphagia
Interventions: BIOLOGICAL: Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Two Treatment Algorithms in Adults With Moderate to Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Adalimumab|DRUG: Prednisone|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymmetrical HFNCO vs Standard HFNCO Post Cardiac Surgery Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoxemic Respiratory Failure
Interventions: DEVICE: Asymmetrical High Flow Nasal Cannula Oxygenation|DEVICE: Conventional High Flow Nasal Cannula Oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Remimazolam (CNS7056) Compared to Propofol for Intravenous Anesthesia During Elective Surgery
Status: COMPLETED
Conditions: Anesthesia, Intravenous
Interventions: DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate GEH200520/GEH200521 (18F) Safety and Tolerability When Used for PET Scans in Patients With Solid Tumour Malignancies
Status: RECRUITING
Conditions: Malignant Solid Tumor|Oncology
Interventions: DRUG: GEH200520 Injection / GEH200521 (18F) Injection - Part A|DIAGNOSTIC_TEST: Dynamic and Static - PET/CT scan|DRUG: GEH200520 Injection / GEH200521 (18F) Injection - Part B|DIAGNOSTIC_TEST: Static - PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction
Status: COMPLETED
Conditions: Chronic Hepatitis B Virus Infection|Chronic Hepatitis C Virus Infection
Interventions: BIOLOGICAL: BMS-914143 (Peginterferon Lambda-1a)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Dose Escalation Study of MLN0128 in Relapsed or Refractory Multiple Myeloma or Waldenstrom Macroglobulinemia
Status: COMPLETED
Conditions: Relapsed Multiple Myeloma|Refractory Multiple Myeloma|Waldenstrom Macroglobulinemia
Interventions: DRUG: MLN0128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer (High-risk Stage III: pT4N1 or pT1 to 4 N2)
Interventions: DRUG: Irinotecan|DRUG: Folfox Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy for Anxiety and Self-esteem: Clinical Trial
Status: COMPLETED
Conditions: Anxiety|Self Esteem
Interventions: OTHER: Intervention Group 2|OTHER: Intervention Group 1|OTHER: Intervention Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tafasitamab and Lenalidomide in People With Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Mantle Cell Lymphoma|MCL
Interventions: DRUG: Tafasitamab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Etonogestrel Contraceptive Implant as Treatment for Endometrial Hyperplasia Without Atypia: A Cohort Study
Status: NOT_YET_RECRUITING
Conditions: Endometrial Hyperplasia Without Atypia
Interventions: DRUG: Etonogestrel implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of 3D Radiotherapy With or Without Erlotinib (Tarceva®) in Patients With Localized Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Erlotinib (Tarceva®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effects of Transcranial Alternative Current Stimulation (tACS) in Chronic Post Stroke Hemianopia
Status: RECRUITING
Conditions: Hemianopsia
Interventions: DEVICE: tACS (transcranial Alternate Current Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients
Status: UNKNOWN
Conditions: Post-operative Pain
Interventions: DRUG: Buprenorphine/Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Susceptibility Testing Guided Antibiotic Selection Strategies in Salvage Helicobacter Pylori Treatment
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Antimicrobial Susceptibility Testing
Interventions: DRUG: Clarithromycin susceptibility dependant strategy|DRUG: 2 susceptible antibiotics (amoxicillin, clarithromycin, metronidazole, tinidazole,levofloxacin, furazolidone and tetracycline )|DRUG: proton pump inhibitor (PPI) and Colloidal Bismuth Pectin|DRUG: amoxicillin and clarithromycin or amoxicillin and furazolidone|DRUG: amoxicillin and furazolidone or amoxicillin and tetracycline|DRUG: amoxicillin and furazolidone or amoxicillin and Tinidazole or amoxicillin and Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin-based Strategies to Prevent Hypoglycemia During Exercise
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Exercise 1|OTHER: Exercise 2|DEVICE: Dexcom G4 Platinum|DRUG: Insulin|DEVICE: Insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-national Study Investigating the Effect and Safety of rFXIII on Transfusion Needs in Patients Undergoing Heart Surgery
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Cardiac Surgery Requiring Cardiopulmonary Bypass
Interventions: DRUG: catridecacog|DRUG: catridecacog|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Expiratory Muscle Strength Training in Improving Bulbar Function and Quality of Life in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Malignant Head and Neck Neoplasm
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Exercise Intervention|OTHER: Expiratory Muscle Strength Training|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Longitudinal Monitoring During Intermittent Fasting Protocols in Obese Adults
Status: NOT_YET_RECRUITING
Conditions: Intermittent Fasting|Obesity|Time Restricted Eating
Interventions: BEHAVIORAL: Modified Alternate Day Fasting|BEHAVIORAL: Time-Restricted Eating|BEHAVIORAL: Weight-loss counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post Market Cohort to Assess the Performance of the Spinal Modulation Neurostimulator System for the Management of Chronic Neuropathic Pain of the Foot and/or Lower Leg
Status: TERMINATED
Conditions: Chronic Neuropathic Pain
Interventions: DEVICE: Implantation with the commercially available Axium neurostimulator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Local Anaesthesia and Remifentanil Sedation Versus Total Intravenous Anaesthesia for Hysteroscopic Surgery in an Ambulatory Surgery Department.
Status: UNKNOWN
Conditions: Conscious Sedation|Remifentanil|Hysteroscopic Surgery|Anesthesia Recovery Period|Ambulatory Surgery
Interventions: OTHER: local anaesthesia and remifentanil sedation|OTHER: total intravenous anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Hyperventilation Syndrome in Difficult Asthma
Status: COMPLETED
Conditions: Difficult Asthma|Severe Persistent Asthma|Hyperventilation Syndrome
Interventions: OTHER: Diagnostic of chronic hyperventilation syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Gabapentin Reduce Quadriceps Muscle Weakness After Anterior Cruciate Ligament Reconstruction?
Status: UNKNOWN
Conditions: Muscle Weakness|Anterior Cruciate Ligament Rupture
Interventions: DRUG: Gabapentin|DRUG: Tramadol|DRUG: Panadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Transauricular Electrical Vagal Nerve Stimulation on Temporal Summation of Pain in Patients With Back Pain
Status: UNKNOWN
Conditions: Pain Intensity
Interventions: DEVICE: Transauricular electrical vagal nerve stimulation|DEVICE: taVNS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
Status: TERMINATED
Conditions: Malignant Melanoma|Medullary Thyroid Cancer|Glioblastoma|Large-Cell Neuroendocrine Carcinoma|Neuroendocrine Prostate Cancer|High Grade Gastroenteropancreatic Neuroendocrine Carcinoma|Other Neuroendocrine Carcinoma|Other Solid Tumors
Interventions: DRUG: Rovalpituzumab tesirine|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Processing in Patients Surviving Delirium. Neuropsychological, EEG and Structural Brain Correlates.
Status: SUSPENDED
Conditions: Septic Encephalopathy|Delirium|Sepsis
Interventions: OTHER: Delirium and with septic encephalopathy.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 90Y-IBRITUMOMAB Tiuxetan and AHCI With HD Chemotherapy and Autologous Transplantation for Relapsed or Resistant NHL
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Blood and Marrow Transplant (BMT)
Interventions: DRUG: 90Y Ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioactive Seed-guided Resection of Cholangiocellular Carcinoma in Cirrhotic Patients
Status: COMPLETED
Conditions: Liver Cancer|Liver Cirrhosis
Interventions: DEVICE: Radioactive Seed Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
Status: RECRUITING
Conditions: Descending Aortic Dissection|Postoperative Pain|Thoracoabdominal Aortic Aneurysm
Interventions: DRUG: Saline|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Of A Single Dose Of Nifedipine Oral Solution Compared To Adalat Capsules In Healthy Female Volunteers
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Nifedipine soft gelatine capsules|DRUG: Nifedipine oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: DFMO in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Difluoromethylornithine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation and Implementation Design of an Epic Systems 30-day Unplanned Readmission Risk Model
Status: COMPLETED
Conditions: Unplanned Hospital Readmissions|Patients at High Risk of Unplanned Readmission
Interventions: BEHAVIORAL: Epic 30-day unplanned readmission risk score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre-Operative Parenteral Nutrition in Malnourished Patients
Status: WITHDRAWN
Conditions: Malnutrition|Inflammatory Bowel Disease 1
Interventions: DIETARY_SUPPLEMENT: Olimel Parenteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BP101 in Healthy Volunteers
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder(HSDD)
Interventions: DRUG: BP101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Resistance and Embolism in Carotid Artery Stenting
Status: UNKNOWN
Conditions: Carotid Stenosis
Interventions: DRUG: Ticlopidine + Ginko biloba|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genicular Radiofrequency Ablation Following Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Genicular Radiofrequency Ablation|PROCEDURE: Sham Genicular Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Myofascial Release in Patients With Axial Spondyloarthritis.
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Myofascial release|OTHER: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine|DRUG: Sertraline|DRUG: citalopram|DRUG: Escitalopram|DRUG: Paroxetine|DRUG: Fluoxetine|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus
Status: COMPLETED
Conditions: Cytomegalovirus Infection|Adenovirus Infection
Interventions: BIOLOGICAL: CMV/AdV specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Causes of Contact Lens Related Dry Eye
Status: COMPLETED
Conditions: Contact Lens Related Dry Eye
Interventions: DEVICE: Opti-Free RepleniSH|DEVICE: ReNu MultiPlus|DEVICE: Contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DRUG: Atropine Sulfate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil and Abacavir Treatment in HIV Patients With Failed Anti-HIV Treatment
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Traditional Acupuncture and Myofascial Trigger Point Dry Needling and Acupressure for Chronic Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Traditional needle acupuncture|PROCEDURE: Myofascial trigger point dry needling|PROCEDURE: Myofascial trigger point acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine and Rituximab in Treating Patients With Previously Untreated or Relapsed Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Tissue Adhesive Material and Suture as Wound-closure Techniques Following Carpal Tunnel Decompression
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: two-component skin adhesive, Glubran Tiss 2|PROCEDURE: skin is stitched with transcutaneous nylon sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Donor FMT|OTHER: Autologous FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 480 STUDY: Phase 2b Study of Locteron Plus Ribavirin to Treat Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Pain Control in Gastric Bypass Surgery Patients
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo (for Pregabalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tiotropium on Walking Capacity in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator
Status: COMPLETED
Conditions: Dry Eye Syndrome|Keratoconjunctivitis Sicca
Interventions: DEVICE: Oculeve Intranasal Neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood Loss in Sites Across the United Kingdom
Status: UNKNOWN
Conditions: Heavy Menstrual Bleeding
Interventions: DEVICE: Librata Endometrial Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Epirubicin, and Cyclophosphamide With or Without Trastuzumab in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: anastrozole|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: goserelin acetate|DRUG: tamoxifen citrate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
Status: RECRUITING
Conditions: Post Acute COVID 19 Syndrome|Memory Impairment|Memory Dysfunction|Cognitive Dysfunction
Interventions: BEHAVIORAL: HOBSCOTCH-PACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Innovative Rehabilitation Treatments and Examination of Their Effectiveness in Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: OTHER: Robot|OTHER: Fizio|OTHER: EXE1|OTHER: EXE2|OTHER: EXE+ROB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Acute Myelogenous Leukemia mRNA Plus Lysate Loaded Dendritic Cell Vaccines
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: Autologous Dendritic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bereaving, But Not Alone : the Development and Actualization of a Mutual Aid Group for Children Who Have Lost a Parent.
Status: COMPLETED
Conditions: Mourning,|Grief,|Bereavement.
Interventions: BEHAVIORAL: Group intervention based on mutual aid.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omega 3 Plus Vaginal Progesterone on Birth Weight of Constitutionally Small for Gestational Age Fetuses
Status: COMPLETED
Conditions: Small for Gestational Age at Delivery
Interventions: DRUG: omega-3 fatty acids|DRUG: vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Manual Therapy on Cervicogenic Headache
Status: COMPLETED
Conditions: Unilateral Headache|Musculoskeletal Neck Pain
Interventions: PROCEDURE: Cervical Spine Mobilization|PROCEDURE: Cervical Spine Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Trexan+Salazopyrin+Oxiklorin+prednisolone + infliximab|DRUG: Trexan+Salazopyrin+Oxiklorin+prednisolone + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)
Status: COMPLETED
Conditions: HIV Infections|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Misoprostol With And Without Transcervical Balloon Catheter In Second Trimester Termination Of Pregnancy
Status: UNKNOWN
Conditions: Pregnancy Trimester, Second|Misoprostol|Catheters|Abortion, Second Trimester
Interventions: DRUG: Misoprostol|DEVICE: Misoprostol/Transcervical catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Massage and Hot Compress Application to Mothers With Premature Babies at Newborn Intensive Care University Effect on Milk Release and Anxiety
Status: COMPLETED
Conditions: Breast Milk Collection|Breast Pumping|Massage Therapy
Interventions: OTHER: breast massage|OTHER: hot compress|OTHER: breast massage-hot compress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety, Tolerability, PK, and PD of DWP213388 After SAD and MAD Administration in Healthy Adult Subjects
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: DWP213388|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triclosan Coated Suture Wound Closure for Peripheral Vascular Surgery: a Prospective Multicenter Study
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: PROCEDURE: triclosan coated suture for surgical wound closure|PROCEDURE: regular sutures for surgical wound closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HFNO in Pneumonia Patients Presenting With Acute Hypoxemic Respiratory Failure
Status: COMPLETED
Conditions: Pneumonia
Interventions: DEVICE: High flow nasal cannula (HFNC)|DEVICE: Noninvasive ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of 360-degree Virtual Reality on Pre-procedural Anxiety in Patients Awaiting Elective Cardiac Surgery Involving a Sternotomy
Status: RECRUITING
Conditions: Cardiac Valve Disease|Aortic Valve Disease|Mitral Valve Disease|Tricuspid Valve Disease
Interventions: BEHAVIORAL: 360-degree Virtual Reality Patient Tour|DIAGNOSTIC_TEST: State Trait Anxiety Inventory|DIAGNOSTIC_TEST: Amsterdam Preoperative Anxiety and Information Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencingvitreoretinopathy
Status: UNKNOWN
Conditions: Rhegmatogenous Retinal Detachment
Interventions: DIAGNOSTIC_TEST: RPE cell collection and single cell heterogeneity study|PROCEDURE: Postoperative intervention|PROCEDURE: Conventional Surgery for Retinal Detachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Submucosal Injection of Indocyanine Green Before Laparoscopic Radical Resection for Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Indocyanine Green
Interventions: PROCEDURE: endoscopic submucosal injection of indocyanine green before laparoscopic radical operation of colorectal cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stimulation Therapy for Inducing Mothers
Status: COMPLETED
Conditions: Induced; Birth|Labor Long|Labor Pain|Breast Pumping|Lactation Induced
Interventions: DEVICE: Electronic breast pump|OTHER: Exogenous oxytocin intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Postoperative Adjuvant Chemotherapy for Stage II Colon Cancer With High Risk Factors(EPAC1)
Status: UNKNOWN
Conditions: Adjuvant Chemotherapy
Interventions: DRUG: CapeOX（Capecitabine+Oxaliplatin）|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment Versus Observation in Elderly Patients With PCNS Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Rituximab, Methotrexate, Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CEDiD Study (COVID-19 Early Diagnosis in Doctors and Healthcare Workers)
Status: UNKNOWN
Conditions: Covid19
Interventions: DEVICE: Wearable Medical Device (Empatica E4)|DIAGNOSTIC_TEST: COVID-19 PCR Swab|DIAGNOSTIC_TEST: Pulse Oximeter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Theobromine on Blood Lipid Parameters in Healthy Subjects
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Theobromine|DIETARY_SUPPLEMENT: Cocoa|DIETARY_SUPPLEMENT: Cocoa and theobromine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Empowering Consumers to 'PREVENT' Diet-related Diseases Through 'OMICS' Sciences
Status: COMPLETED
Conditions: Overweight|Obesity|Metabolic Syndrome
Interventions: OTHER: Personalized Nutrition Plan|OTHER: Non-Personalized Nutrition Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Recombinant Factor XIII in Patients With Congenital Factor Xlll Deficiency
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Congenital FXIII Deficiency
Interventions: DRUG: catridecacog
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flaxseed in Preventing Breast Cancer in Premenopausal Women at Risk of Developing Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Precancerous Condition
Interventions: DIETARY_SUPPLEMENT: Ground Flaxseed|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms
Status: RECRUITING
Conditions: Candidiasis, Vulvovaginal|Recurrent Candidiasis of Vagina
Interventions: DRUG: Fluconazole|DEVICE: L-Mesitran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tamoxifen's Efficacy for ER/PR Negative,ER-beta Positive Operable Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CSP #512 - Options in Management With Anti-Retrovirals
Status: COMPLETED
Conditions: AIDS|HIV Infections
Interventions: OTHER: No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP|DRUG: Standard ART vs Mega ART|OTHER: No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP|DRUG: Standard ART vs Mega ART|OTHER: No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP|DRUG: Standard ART vs Mega ART|OTHER: No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP|DRUG: Standard ART vs Mega ART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Evaluation and Treatment of Repetetive Behaviors in Autism
Status: TERMINATED
Conditions: Autism|Asperger Disorder|Other Developmental Pervasive Disorder
Interventions: PROCEDURE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin and Furosemide Drug-Drug Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lesinurad 400 mg|DRUG: Metformin 850 mg|DRUG: Furosemide 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a Cell-derived Influenza Vaccine in Adults Aged >= 18 and <= 64, Plus Revaccination
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell-Derived Trivalent Subunit Influenza Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sonoclot to Evaluate Thrombotic Risk in Proteinuric Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Complications|Proteinuria in Pregnancy|Chronic Kidney Diseases|Venous Thromboembolism
Interventions: DIAGNOSTIC_TEST: Viscoelastic haemostasis monitor output
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Assess Allisartan Isoproxil/Sustained-Release Indapamide in Patients With Essential Hypertension Uncontrolled With Allisartan Isoproxil
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Allisartan Isoproxil/Sustained-Release Indapamide|DRUG: Allisartan Isoproxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of AZD7442 in Healthy Chinese Adults
Status: COMPLETED
Conditions: Coronavirus Disease 2019 (COVID-19)|Healthy Volunteer
Interventions: DRUG: AZD7442 IM|DRUG: Placebo IM|DRUG: AZD7442 IM|DRUG: Placebo IM|DRUG: AZD7442 IV|DRUG: Placebo IV|DRUG: AZD7442 IV|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intravital Microscopy in Evaluating Patients With Primary Peritoneal, Fallopian Tube, or Stage IA-IV Ovarian Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma|Stage I Ovarian Cancer|Stage IA Ovarian Cancer|Stage IB Ovarian Cancer|Stage IC Ovarian Cancer|Stage II Ovarian Cancer|Stage IIA Ovarian Cancer|Stage IIB Ovarian Cancer|Stage IIC Ovarian Cancer|Stage III Ovarian Cancer|Stage IIIA Ovarian Cancer|Stage IIIB Ovarian Cancer|Stage IIIC Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: PROCEDURE: Diagnostic Microscopy|DRUG: Fluorescein Sodium Injection|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of PD-1 Inhibitor in Combination With Gemcitabine/Cisplatin for Advancer BTCs
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: PD-1 inhibitor + Gemcitabine + Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melody PB1016 Surveillance Study
Status: COMPLETED
Conditions: Dysfunctional RVOT Conduits in Patients With Congenital Heart Defects
Interventions: DEVICE: Melody Transcatheter Pulmonary Valve PB1016
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Chemopreventive Regimens to Prevent Malaria and Improve Birth Outcomes in Uganda
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Sulfadoxine-pyrimethamine (SP)|DRUG: Dihydroartemisinin-piperaquine (DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY2875358 in Japanese Participants With Advanced Cancer
Status: COMPLETED
Conditions: Solid Tumors|Lymphoma|Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: LY2875358|DRUG: Erlotinib|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcers
Interventions: BIOLOGICAL: HP-802-247|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hypothermic Versus Normothermic Ex-vivo Preservation.
Status: UNKNOWN
Conditions: End Stage Liver DIsease
Interventions: DEVICE: Hypothermic Machine Perfusion|DEVICE: Normothermic Machine Perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FAC Versus FAC Plus Weekly Paclitaxel as Adjuvant Treatment of Node Negative High Risk Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fluorouracil|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Fascia Iliaca Block for Acute Hip Fractures
Status: COMPLETED
Conditions: Hip Fractures|Neuromuscular Blockade|Respiratory Morbidity|Delirium|Fascia Iliaca Block|Pain
Interventions: PROCEDURE: Continuous fascia iliaca block|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Lung Recruitment Maneuver in 24-32 Weekers, and the Incidence of Bronchopulmonary Dysplasia
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DEVICE: lung recruitment maneuver (LRM) with DrageerVN500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population Pharmacokinetics
Status: UNKNOWN
Conditions: Malaria, Falciparum
Interventions: DIETARY_SUPPLEMENT: Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LBH589 in Combination With Capecitabine Plus/Minus (±) Lapatinib in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: LBH589|DRUG: Capecitabine|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Trial of a Group Psychological Intervention for Postnatal Depression in British Mother's of South Asian Origin
Status: COMPLETED
Conditions: Depression, Postpartum|Postnatal Depression in British South Asian Women
Interventions: BEHAVIORAL: Culturally adapted psychological intervention (Positive Health Programme)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: PROCEDURE: EEG|GENETIC: Apolipoprotein genotype|BIOLOGICAL: Serum NfL measurements|OTHER: Preoperative neurocognitive evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing the Glycaemic Index of Two Different Cultivars of Date Fruit
Status: COMPLETED
Conditions: GI Glycaemic Index Healthy Volunteers|GL Glycaemic Load Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Birhi|DIETARY_SUPPLEMENT: Khassab|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE