pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Adhesion Study Between ZTlido 1.8% and Three Over-the-counter External Analgesic Lidocaine-containing Patches
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ZTlido (Lidocaine Topical System) 1.8%|DRUG: Salonpas (Lidocaine Patch 4%)|DRUG: Aspercreme (Lidocaine Patch 4%)|DRUG: IcyHot (Lidocaine 4% + Menthol 1% Patch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Remimazolam and Propofol Anesthesia in Elderly Patients
Status: COMPLETED
Conditions: Hemodynamics
Interventions: DRUG: Remimazolam Besylate 6 mg/kg/hr|DRUG: Remimazolam Besylate 12 mg/kg/hr|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Type IV Thoracoabdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Thoracoabdominal Aortic Aneurysm
Interventions: DEVICE: GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With ASP2151 in Subjects With Recurrent Episodes of Genital Herpes
Status: COMPLETED
Conditions: Herpes Genitalis
Interventions: DRUG: ASP2151|DRUG: valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain and Vitamin D
Status: UNKNOWN
Conditions: Chronic Musculoskeletal Pain|Vitamin D Supplementation
Interventions: DRUG: vitamin D (cholecalciferol)|DRUG: Placebo, similar in appearance and taste to cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurotrophic Factors, Tight Junction Proteins, and Cytokines in IBS
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Tight Junction Alteration|Pathophysiology
Interventions: PROCEDURE: colonoscopic mucosal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Levalbuterol HCl|DRUG: Levalbuterol HCl|DRUG: Albuterol Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Different Doses of 0382 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MEDI0382|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NVG-291 in Spinal Cord Injury Subjects
Status: RECRUITING
Conditions: Spinal Cord Injuries|Chronic Spinal Cord Injury|Subacute Spinal Cord Injury
Interventions: DRUG: NVG-291
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Multi-Center, Randomized, Double-blind, Positive Controlled Clinical Trial of Bicyclol in the Treatment of Acute DILI
Status: UNKNOWN
Conditions: Drug-Induced Acute Liver Injury
Interventions: DRUG: bicyclol, 25mg/ tablet|DRUG: polyene phosphatidylcholine capsules, 228mg/ particle.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: myo-inositol|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampus DBS in Treatment-resistant Schizophrenia
Status: RECRUITING
Conditions: Treatment-resistant Schizophrenia
Interventions: DEVICE: On-Stimulation|DEVICE: Off-Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Neurological Effects of EryDex on Subjects With A-T
Status: RECRUITING
Conditions: Ataxia Telangiectasia
Interventions: DRUG: Dexamethasone sodium phosphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-course Preoperative Chemoradiotherapy Followed by Delayed Operation for Locally Advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Radiation: short-course preoperative chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of COVID-19 Vaccine as Booster Vaccination in Adults 18 Years of Age or Older
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Vaccine (CHO Cell) LYB001|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MINIALO-VELCADE2005: A Study of Bortezomib (Velcade) Treated Multiple Myeloma Patients Pre and Post Allogeneic Haematopoietic Progenitor Cell Transplant With no Myeloablative Conditioning
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: dexamethasone|DRUG: Fludarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety and Efficacy of Drospirenone and Ethinyl Estradiol (YAZ) Versus Placebo In HS
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: drospirenone and ethinyl estradiol (YAZ)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robot Based Gait Training Therapy for Pediatric Population With Cerebral Palsy Using the CPWalker
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: CPWalker Robotic Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Palindrome vs. BioFlo DuraMax Dialysis Catheters
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: DEVICE: Bioflo Dialysis Catheter|DEVICE: Palindrome Dialysis Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phoenix Thera-Lase for Treating Chronic Pain in Patients Taking Opioid on a PRN Basis
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: Low level 1 Watt|DEVICE: Phoenix Thera-Lase System 42|DEVICE: Phoenix Thera-Lase System 74
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Combined With Anlotinib in the First Line Therapy for R/M HNSCC With CPS≥1
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Secretin-enhanced Magnetic Resonance Cholangiopancreatography (S-MRCP) to Endoscopic Pancreatic Function Test (ePFT) in Diagnosing Pancreatic Exocrine Insufficiency
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Synthetic Human Secretin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: To Assess the Efficacy of Midodrine in Prevention of Cirrhosis Related Complications in Children Awaiting Liver Transplantation.
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: DRUG: Midodrine Oral Tablet|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance Using Peripheral Blood Clonotypic Mass Spectrometry
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elrantamab|DEVICE: EasyM|DEVICE: clonoSEQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand Ligament Reconstructions With Knee Collateral Ligament Allografts
Status: UNKNOWN
Conditions: Hand Injuries|Wrist Injuries|Ligament Injury|Ligament Rupture|Ligament Avulsion
Interventions: PROCEDURE: Ligament Reconstruction with Allograft Ligament
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery
Status: UNKNOWN
Conditions: Dexmedetomidine|Delirium|Cardiac Surgery
Interventions: DRUG: dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Co-Arinate FDC|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Tetrahydrouridine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
Status: RECRUITING
Conditions: Coronary Artery Disease|Chest Syndrome|Acute Myocardial Infarction|Heart Failure|Stroke|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: CT angiography, FFR-CT and stress CT myocardial perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Biotin Supplementation be Used to Mask hCG Abuse?
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Choriogonadotropin Alpha|DIETARY_SUPPLEMENT: biotin|OTHER: Microcellulose filler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect and Experience of PreHomeCare of Preterm Infants Using Telecommunication and Smartphone Application
Status: COMPLETED
Conditions: Infants, Premature|Breastfeeding|Telecommunication|Patient Discharge|Nursing
Interventions: OTHER: App group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Excision and Reconstruction of the Natal Cleft With a Parasacral Perforator Flap Versus Open Excision With Secondary Healing, in the Management of Sacrococcygeal Pilonidal Disease.
Status: TERMINATED
Conditions: Pilonidal Disease
Interventions: PROCEDURE: parasacral flap reconstruction|PROCEDURE: open excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orelabrutinib in Combination With R2 Regimen for R/R CD20+ B-cell Lymphoma
Status: UNKNOWN
Conditions: B-cell Lymphoma
Interventions: DRUG: Orelabrutinib tablet|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the REG1 Anticoagulation System Compared Heparin in Subjects With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome (ACS)
Interventions: DRUG: REG1|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: a Randomized Multicenter Trial Comparing Vacuum Assisted Delivery With the New Device "iCUP" Versus the Reference Cup.
Status: COMPLETED
Conditions: Vacuum Extraction, Obstetrical|Randomized Controlled Trials|Failures, Medical Device|Maternal Lesions|Neonatal Lesions
Interventions: DEVICE: iCup|DEVICE: reference cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Patients With COPD.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DRUG: BI 1744CL
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CD19-Targeted CAR-T Therapy for Relapsed/Refractory CD19+ B Cell Leukemia and Lymphoma
Status: RECRUITING
Conditions: Leukemia|Lymphoma|Leukemia, B-Cell|Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: BIOLOGICAL: CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating PK, PD, Efficacy, Safety, and Immunogenicity of Biosimilar Denosumab (GP2411) in Patients With Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Women With Osteoporosis
Interventions: BIOLOGICAL: GP2411|BIOLOGICAL: EU-Prolia (EU-authorized Prolia®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
Status: COMPLETED
Conditions: Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural
Interventions: PROCEDURE: bilateral Ultrasound guided erector spinae plane (ESP) block|PROCEDURE: quadratus lumborum block|PROCEDURE: lumbar epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma
Status: TERMINATED
Conditions: Synovial Sarcoma
Interventions: DRUG: Ramucirumab|DRUG: Gemcitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CardioMetabolic Program Meets eHealth: Redesign and Evaluation for Optimal Reach and Impact
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome|Pre-diabetes|Type 2 Diabetes|Cardiovascular Disease
Interventions: BEHAVIORAL: eCMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: BIOLOGICAL: GVAX Pancreas|BIOLOGICAL: CRS-207|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Gastrointestinal Disorder Screening Program - A Randomized Controlled Trial
Status: COMPLETED
Conditions: Non-erosive Gastroesophageal Reflux Disease|Functional Dyspepsia|Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Pioglitazone Treatment in Patients With Type 2 Diabetes Mellitus and Covid-19
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone 30 mg|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XIENCE Xpedition/Alpine/Sierra in Routine Clinical Practice
Status: ACTIVE_NOT_RECRUITING
Conditions: Percutaneous Transluminal Coronary Angioplasty|Coronary Artery Disease
Interventions: DEVICE: XIENCE Xpedition/Alpine/Sierra
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study Of Neoadjuvant Chemotherapy In Borderline Resectable Pancreatic Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-atherosclerotic Activity of Karinat in Postmenopausal Women
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Karinat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Antineoplaston Therapy in Treating Patients With Intermediate-Grade Stage II - IV Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-hodgkins Lymphoma
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Memory for Sleep Treatment Content With Text Messages
Status: COMPLETED
Conditions: Sleep Wake Disorders
Interventions: OTHER: PUSH text messages|OTHER: PULL text messages|BEHAVIORAL: TranS-C|BEHAVIORAL: PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: UNKNOWN
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage III Non-Small Cell Lung Cancer|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Metformin Hydrochloride|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioequivalence of Cefdinir and Omnicef 300 mg Capsule Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefdinir 300 mg Capsule (Sandoz, Austria)|DRUG: Omnicef Cefdinir 300 mg Capsule (Abbott Laboratories, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder
Status: RECRUITING
Conditions: Standard of Care|Standard of Care + CBT4CBT|Standard of Care + CBT4CBT + RC
Interventions: BEHAVIORAL: CBT4CBT|BEHAVIORAL: RC|BEHAVIORAL: Sandard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Geniculate Artery Embolization for Treatment of Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: PROCEDURE: Transcatheter arterial embolization|DEVICE: Embozene™ Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Activity, Independence and Stability in Early Dementia
Status: COMPLETED
Conditions: Dementia MCI (Mild Cognitive Impairment)
Interventions: OTHER: High intensity supervision arm|OTHER: Moderate intensity supervision arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TTT Versus TTT and Triamcinolone to Decrease Exudation in Choroidal Melanoma After Proton Beam Therapy
Status: UNKNOWN
Conditions: Exudative Retinal Detachment|Uveal Melanoma
Interventions: DRUG: Triamcinolone Acetonide|PROCEDURE: Transpupillary thermotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency Assessment of the Methodology for the Follow-up of Patients With Knee Prostheses
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: Total knee prosthesis with medial condylar stabilization|PROCEDURE: Total knee prosthesis with central pivot stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vilazodone for Menopausal Hot Flashes
Status: COMPLETED
Conditions: Hot Flushes
Interventions: DRUG: vilazodone|DRUG: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: anastrozole|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Participants
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Therapy With Paclitaxel and Carboplatin in Operable Locally Advanced Head and Neck Cancer Patients
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: paclitaxel/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Oral Isotretinoin on Skin Thickness and Elasticity in Patients With Atrophic Acne Scar
Status: COMPLETED
Conditions: Acne Vulgaris|Isotretinoin|Atrophic Acne Scar
Interventions: DRUG: Isotretinoin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platelet Inhibition in Patients With Systolic Heart Failure
Status: COMPLETED
Conditions: Systolic Heart Failure
Interventions: DRUG: Prasugrel 10 mg daily x 2 weeks|DRUG: Clopidogrel 75 mg daily x 2 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Pre-operative Ultrasound FICB Group|PROCEDURE: Intra-operative FICB Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: PI3K inhibitor BKM120|DRUG: pemetrexed disodium|DRUG: carboplatin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Codex: Study of Inodiftagene Vixteplasmid (BC-819) in Unresponsive NMIBC
Status: TERMINATED
Conditions: Non-muscle Invasive Bladder Cancer (NMIBC)
Interventions: DRUG: inodiftagene vixteplasmid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineal Local Infiltration Study
Status: TERMINATED
Conditions: Second Degree Perineal Tear During Delivery - Delivered|Episiotomy; Complications|Anesthesia, Local
Interventions: DRUG: Bupivacaine 0.5%+Epinephrine 50mc|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QUILT-3.019: Phase 2 Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer|Metastatic Colorectal Cancer
Interventions: DRUG: NPC-1C/NEO-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of the Consumption of Different Products Cocoa Derivatives at the Risk of Crystallization of Uric Acid in Urine of Volunteers.
Status: COMPLETED
Conditions: Lithiasis, Urinary
Interventions: DIETARY_SUPPLEMENT: Intervention 0|DIETARY_SUPPLEMENT: Intervention 1|DIETARY_SUPPLEMENT: Intervention 2|DIETARY_SUPPLEMENT: Intervention 3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuro-rehabilitation Training Effects on Motion and Quality of Life After Acute Stroke and Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Exergaming group|OTHER: Physiotherapy|OTHER: Exergaming group 2/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure (CPAP) for Fatigue in Patients With Multiple Sclerosis (MS) and Obstructive Sleep Apnea (OSA)
Status: WITHDRAWN
Conditions: Fatigue|Multiple Sclerosis|Sleep Apnea
Interventions: DEVICE: Auto-titration CPAP|DEVICE: Sham-CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization and Quantification of Platelet/Leukocyte Aggregates in Patients With Suspected Heparin-induced Thrombocytopenia
Status: RECRUITING
Conditions: Heparin-induced Thrombocytopenia|HIT|Platelet Activation|Platelets|Leukocytes|Platelet/Leukocyte Aggregates|HITSTREAM|Flow Cytometry
Interventions: BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of the Ivabradine on Reduction of Inflammatory Markers in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucagon-like Peptide 1 (GLP-1) and Endothelial Dysfunction in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: GLP-1 infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Inspiratory Muscle Training (EMI) on Inspiratory Muscle Strength, Pulmonary Capacity and Performance in Soccer Players
Status: COMPLETED
Conditions: Breathing Exercises: Inspiratory Muscle Training
Interventions: DEVICE: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Different Sugar Replacer Combinations on Gastrointestinal Tolerance
Status: COMPLETED
Conditions: Tolerance|Healthy Population
Interventions: OTHER: Acute intake of one of the products (active comparator 1 to 9) or Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)
Status: NOT_YET_RECRUITING
Conditions: Generalized Lipodystrophy
Interventions: DRUG: mibavademab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Efficacy of Infliximab in Chinese Participants With Moderate to Severe Plaque-type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Placebo|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Study of in Men With PSA Progression on Abi for CR or CS PC (Bio-STAMP)
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Dutasteride|DRUG: Abiraterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium and Rotational Thromboelastometry (ROTEM) in Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Magnesium Sulfate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics After Multiple Oral Doses of BIBR 1048 MS Capsule in Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBR 1048 MS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulation of Bone Formation in Renal Osteodystrophy
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Renal Osteodystrophy
Interventions: DRUG: 1 alpha D2|DRUG: 1,25 dihydroxy vitamin D3|DRUG: Sevelamer HCl|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: mRNA-1468|BIOLOGICAL: Placebo|BIOLOGICAL: Shingrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neurostimulation-enhanced Behavioral Remediation of Social Cognition in Schizophrenia
Status: WITHDRAWN
Conditions: Behaviors and Mental Disorders
Interventions: DEVICE: transcranial Direct Current Stimulation tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 4, Conversion Study of Hectorol® Injection to Hectorol® Capsules in Stage 5 CKD Patients on Dialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism
Interventions: DRUG: Hectorol® (doxercalciferol capsules)|DRUG: doxercalciferol capsules, Hectorol®|DRUG: doxercalciferol capsules, Hectorol® capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Clinical Efficacy Of A Herbal And A Non-Herbal Mouthwash On Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentinal Hypersensitivity
Interventions: OTHER: placebo mouthwash|OTHER: Herbal Mouthwash|OTHER: Non Herbal Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Validation and Biological Index Studies on the Improved Social Function of ASD by 40 Hz tACS
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: 40 Hz tACS intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirabegron for Female OAB Patients: Comparison of Daytime and Nighttime Dosing
Status: RECRUITING
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: daytime dosing of mirabegron|DRUG: nighttime dosing of mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist (NAVA) in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: PSV and NAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Tourniquet Application Methods in Primary Total Knee Arthroplasty Surgery
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Total knee arthroplasty performed under tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin for the Treatment of Hypersomnia
Status: COMPLETED
Conditions: Hypersomnia|Idiopathic Hypersomnia|Narcolepsy
Interventions: DRUG: Clarithromycin followed by placebo|DRUG: Placebo then Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD)
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: GENETIC: Mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychophysiological Effects of Controlled Respiration and Mindfulness
Status: COMPLETED
Conditions: Stress, Physiological|Stress, Emotional|Insomnia
Interventions: BEHAVIORAL: Mindfulness Meditation|BEHAVIORAL: Cyclic Sighing Breathing|BEHAVIORAL: Box Breathing|BEHAVIORAL: Cyclic Hyperventilation with Retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion
Status: COMPLETED
Conditions: Hysteroscopy|Intrauterine Adhesion
Interventions: PROCEDURE: Hysteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Daily Nutritional Supplementation in Combination With a Eurhythmics Training (NUDAL)
Status: COMPLETED
Conditions: Improvement of Functionality
Interventions: DIETARY_SUPPLEMENT: ONS+JDR|DIETARY_SUPPLEMENT: JDR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection
Status: COMPLETED
Conditions: Viral Hepatitis C|HIV
Interventions: DRUG: Sofosbuvir/Ledipasvir fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival
Status: TERMINATED
Conditions: Bladder Cancer|Bladder Urothelial Carcinoma
Interventions: PROCEDURE: re-TURBT|DRUG: 6 weeks BCG instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated High Sensitivity C-reactive Protein (Hs-CRP)
Status: COMPLETED
Conditions: Prior Acute Myocardial Infarction|Evidence of Systemic Inflammation (C Reactive Protein Plasma >2 mg/l)|Reduced Left Ventricle Ejection Fraction (<50%)|Symptoms of Heart Failure (NYHA Class II-III)
Interventions: OTHER: Cardiopulmonary exercise test|OTHER: Echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Dose Study Of PF-04171327 And Prednisone On Carbohydrate Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04171327|DRUG: PF-04171327|DRUG: Prednisone|DRUG: PF-04171327|DRUG: PF-04171327|DRUG: Prednisone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine and 5-HT3 With or Without Dexamethasone to Prevent CINV
Status: RECRUITING
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: 5HT3RA+Olanzapine|DRUG: 5HT3RA+Olanzapine+Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrium Reservoir Function Modulation in Patients With Atrial Fibrillation: Digoxin Versus Beta Blocker
Status: UNKNOWN
Conditions: Atrial Fibrillation|Left Atrial Rhythm
Interventions: DRUG: Digoxin 0.25 mg|DRUG: Bisoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Ketamine Versus Intranasal Fentanyl
Status: COMPLETED
Conditions: Multiple Trauma|Pain, Acute
Interventions: DRUG: Placebo|DRUG: Ketamine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants with Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis|Systemic Lupus Erythematosus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auto Transplantation of Wisdom Teeth
Status: RECRUITING
Conditions: Autotransplantation of Wisdom Teeth|Patelet Rich Fibrin
Interventions: PROCEDURE: Autotransplantation with PRF|PROCEDURE: Autotransplatation Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Professional Peer Resilience Initiative
Status: ENROLLING_BY_INVITATION
Conditions: Stress|Stress Disorder|Stress, Psychological|Trauma, Psychological|Anxiety|Anxiety State|Post Traumatic Stress Disorder|Secondary Traumatic Stress|Professional Quality of Life|Stress Related Disorder|Stress Reaction|Stress Risk|Mental Resilience|Emotional Resilience
Interventions: BEHAVIORAL: MinnRAP Peer Support Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Salvage Radiotherapy With or Without Enzalutamide in Recurrent Prostate Cancer Following Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation Therapy|DRUG: Enzalutamide|DRUG: Bicalutamide|DRUG: GnRH analog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Luspatercept for the Treatment of Anemia Due to MDS With del5q, Refractory/Resistant/Intolerant to Prior Treatments, RBC-TD
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Del(5Q)|Anemia|Transfusion-dependent Anemia
Interventions: DRUG: Luspatercept Injection [Reblozyl]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Preventive Regenerative Peripheral Nerve Interface(RPNI) Reconstruction in Amputees
Status: UNKNOWN
Conditions: Amputation Neuroma
Interventions: PROCEDURE: preventive regenerative peripheral nerve interface reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Imatinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Patients Who Have Received Allo-HSCT
Interventions: DRUG: Imatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Fibrosis
Interventions: BIOLOGICAL: Tigerase®|BIOLOGICAL: Pulmozyme®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LYell SYndrome MEsenchymal Stromal Cells Treatment
Status: NOT_YET_RECRUITING
Conditions: Epidermal Necrolysis|Lyell Syndrome|Toxic Epidermal Necrolysis|Overlap Syndrome|Mesenchymal Stromal Cells|Adipose Derived Stromal Cells
Interventions: DRUG: Adipose derived stromal cells intravenously injected
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Placebo|DRUG: Topical corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Aphasia
Interventions: DEVICE: Active TMS|DEVICE: Sham TMS|BEHAVIORAL: CILT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Multimodal Physiotherapy for Acute / Sub-acute Cervical Radiculopathy
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: OTHER: Multimodal physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Combination With Chemoradiation in Resectable Gastric Cancer
Status: TERMINATED
Conditions: Subjects With Resectable Local or Locally Advanced, Non-Metastatic (T2-T4, N0-N3, M0; Stages II and III) and Histologically-Confirmed Intestinal GC
Interventions: DRUG: Gefitinib, 5-fluorouracil, leucovorin and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients
Status: COMPLETED
Conditions: Macular Edema|Diabetic Macular Edema|Neovascular Age-related Macular Degeneration|Retinal Vein Occlusion
Interventions: DRUG: MHU650
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)
Status: NOT_YET_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: BoNT A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT