pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of LSVT LOUD for Mandarin-speaking Individuals With Hypokinetic Dysarthria Due to Parkinson's Disease
Status: UNKNOWN
Conditions: Hypokinetic Dysathria
Interventions: BEHAVIORAL: Lee Silverman Voice Treatment (SVLT) LOUD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: zileuton|DRUG: azathioprine/prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis
Status: COMPLETED
Conditions: Chondrocalcinosis
Interventions: DRUG: Colchicine opocalcium 1mg|DRUG: Prednisone : Cortancyl 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mulligan's Bent Leg Raise Technique in Healthy Females
Status: COMPLETED
Conditions: Hamstring Contractures
Interventions: OTHER: Mulligan Bent Leg Raise Technique|OTHER: Static Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of AGN 203818 for Pain Associated With Fibromyalgia Syndrome
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DRUG: placebo|DRUG: AGN 203818|DRUG: AGN 203818|DRUG: AGN 203818
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Pentoxifylline 400 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alpha-2b Versus Hydroxyurea in Polycythemia Vera
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: Peg-P-IFN-alpha-2b (AOP2014)|DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Educational Interventions in the Prevention of Caries in Patients With Orthodontics
Status: NOT_YET_RECRUITING
Conditions: Dental Caries|Tooth Demineralization
Interventions: OTHER: Conventional Educational interventions|BEHAVIORAL: Motivational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Norwegian Cartilage Project - Microfracture
Status: COMPLETED
Conditions: Knee Injury|Cartilage Injury
Interventions: PROCEDURE: Arthroscopic microfracture (MF)|PROCEDURE: Arthroscopic debridement (AD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK/PD Pediatric ADHD Classroom Study
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate HCl ER tablets 1|DRUG: Placebo|DRUG: Methylphenidate HCl ER tablets 2|DRUG: Methylphenidate HCl ER for suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.
Status: RECRUITING
Conditions: Erector Spinae Plane Block|Super Obese Patients|Bariatric Surgery
Interventions: PROCEDURE: ESPB|PROCEDURE: local anaesthetic infiltration|DRUG: midazolam and lidocaine|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Temozolomide or Bevacizumab and Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Retrograde Recanalization of Infrainguinal Arterial Occlusive Disease.
Status: UNKNOWN
Conditions: Critical Limb Ischemia
Interventions: PROCEDURE: retrograde access for re-canalization of infra-inguinal arterial occlusive disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Applesauce Study of Verapamil HCl Extended-Release Capsules 300 mg and Verelan® PM Extended-Release Capsules 300 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Verapamil Hydrochloride Extended-Release Capsules, 300 mg|DRUG: Verelan® PM Extended-Release Capsules, 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Esreboxetine|DRUG: Esreboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-neural Dexmedetomidine Versus Dexamethasone for Supraaclavicular Block Adjuvant to Bupivacaine Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Brachial Plexus Block
Interventions: DRUG: Dexmedetomidine injection|DRUG: Dexamethasone|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women
Status: RECRUITING
Conditions: Breast Cancer Female|Health Knowledge, Attitudes, Practice|Cancer Screening|Health Disparities
Interventions: BEHAVIORAL: Faith in Action! Church-based Navigation Model|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Helping Behavior|Help-Seeking Behavior|Stress|Relationship, Social|Sexual Assault|Sexual Violence|Social Interaction
Interventions: BEHAVIORAL: Dyadic CARE|BEHAVIORAL: Supporter-Only CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D as a Key Player in Rheumatoid Arthritis
Status: COMPLETED
Conditions: the Immunomodulatory Effect
Interventions: DRUG: Vitamin D|DRUG: Steroid Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Inflammatory Markers
Status: COMPLETED
Conditions: Vitamin D Deficiency|Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: cholecalciferol (Euro-Pharm International, Canada)|DIETARY_SUPPLEMENT: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency-based Speckle Tracking Echocardiography to Evaluate Diastolic Function
Status: COMPLETED
Conditions: Heart Failure, Diastolic
Interventions: DEVICE: Echocardiography system Ultra DCI Model 5000|DEVICE: Echocardiography machine GE Vivid E9|DEVICE: Diastolic function assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DRUG: Inclisiran Sodium for injection|DRUG: Placebo|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: ITCA 650 Osmotic Mini Pump 20/60 mcg/day|DRUG: ITCA 650 Osmotic Mini Pump 60 mcg/day|DRUG: Metformin|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Status: COMPLETED
Conditions: Childhood Obesity|Excessive Weight Gain in Pregnancy With Baby Delivered|Dietary Modification|Healthy Lifestyle Habits
Interventions: BEHAVIORAL: Nutrition & Exercise Lifestyle Intervention Program (NELIP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Scaling-Up Stepped Care for Women's Mental Health in Primary Care in an LMIC
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Stepped Care|BEHAVIORAL: Standard of Care plus Healthy Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone)
Status: COMPLETED
Conditions: Growth Hormone Disorder|Pituitary Dwarfism|Hypopituitarism
Interventions: DRUG: somatropin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Glioma|High Grade Glioma
Interventions: BIOLOGICAL: TTRNA-DC vaccines with GM-CSF|DRUG: Dose-intensified TMZ|BIOLOGICAL: Autologous Hematopoietic Stem cells (HSCs)|BIOLOGICAL: TTRNA-xALT|DRUG: Td vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Energy Technique Versus Strain Counterstrain for Upper Trapezius Myofascial Pain Syndrome
Status: RECRUITING
Conditions: Physical Therapy
Interventions: PROCEDURE: Muscle energy technique combined with the physical therapy program.|PROCEDURE: Strain counterstrain technique combined with the physical therapy program|PROCEDURE: The physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract
Status: COMPLETED
Conditions: Pancreatic Cyst|Pancreatic Neoplasms|Pancreatic Adenoma|Pancreatic Cancer|Pancreatic Islet Cell Tumors|Lymph Node Mass|Lymphadenopathy|GIST
Interventions: DEVICE: Endoscopic ultrasound fine needle aspiration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.
Status: RECRUITING
Conditions: Peri-Implantitis
Interventions: PROCEDURE: Non-surgical treatment of peri-implantitis with mechanical debridement|PROCEDURE: Non-surgical treatment of peri-implantitis with air polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: PF-06882961|DRUG: Atorvastatin|DRUG: Midazolam|DRUG: Levonorgestrel & Ethinyl Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer. NK-ACT-BC_2020
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Cyclophosphamide|DRUG: Trastuzumab|DRUG: Pertuzumab|BIOLOGICAL: NK cells|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Early Gastric Cancers Using Confocal Laser Endomicroscopy
Status: COMPLETED
Conditions: Stomach Neoplasms|Precancerous Conditions
Interventions: DEVICE: Endomicroscope (Pentax, Tokyo, Japan)|DEVICE: Gastroscopes (Pentax, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Demonstrate the Safety and Preliminary Efficacy of 18F-FLT in Patients With Solid Tumours or Lymphoma
Status: TERMINATED
Conditions: Brain Cancer|Cancer|Solid Tumor|Lymphoma
Interventions: BIOLOGICAL: 18F-FLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Different Interventions to Reduce Bruising Following CCH-Aaes Treatment for Cellulite of the Buttocks
Status: COMPLETED
Conditions: Edematous Fibrosclerotic Panniculopathy|Cellulite
Interventions: DRUG: CCH-aaes|DRUG: Antifibrinolytic Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baricitinib for the Treatment of Ocular Mucous Membrane Pemphigoid
Status: TERMINATED
Conditions: Mucous Membrane Pemphigoid|Cicatrizing Conjunctivitis
Interventions: DRUG: Baricitinib 2 MG [Olumiant]|DRUG: Methotrexate|DRUG: Azathioprine|DRUG: Mycophenolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Direct Factor Xa-inhibitor Apixaban in Patients With Acute Symptomatic Deep-vein Thrombosis-The Botticelli DVT Study
Status: COMPLETED
Conditions: Deep-Vein Thrombosis
Interventions: DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Gaming App to Improve Adherence to PrEP
Status: NOT_YET_RECRUITING
Conditions: Medication Adherence|HIV/AIDS
Interventions: BEHAVIORAL: Multilevel Gaming Adherence Intervention|BEHAVIORAL: Treatment as Usual +
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: "WakeUp" for Vigilance Following Lunch
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: "Wake Up"|DIETARY_SUPPLEMENT: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: alveolar ridge preservation with synthetic bone|PROCEDURE: alveolar ridge preservation with bovine collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Dysfunction in Tetralogy of Fallot: Inhibition of the Renin-angiotensin-aldosterone System
Status: UNKNOWN
Conditions: Tetralogy of Fallot|Heart Defects, Congenital|Ventricular Dysfunction, Right
Interventions: DRUG: Losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Adult and Adolescent Subjects With PAR (Perennial Allergic Rhinitis)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Beclomethasone dipropionate hydrofluoroalkane HFA Nasal Aerosol|DRUG: Placebo Nasal Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transbucal Dexmedetomidine for Prevention of Sevoflurane Emergence Agitation in Pre-school Children
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: Dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma
Status: TERMINATED
Conditions: Metastatic Osteosarcoma
Interventions: DRUG: Sm-EDTMP|OTHER: Autologous Stem Cell Infusion|RADIATION: External Beam Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerament Treatment of Fracture Defects
Status: COMPLETED
Conditions: AO 41-B2 and AO 41-B3 Tibia Fractures
Interventions: DEVICE: CERAMENT™|BONE VOID FILLER|PROCEDURE: Autologous cancellous bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine
Status: UNKNOWN
Conditions: Heart Failure|Cardiogenic Shock|Tachycardia
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effects on Barrier Impairment, Clinical Features and Bacterial Colonization of Topical Formulations in Patients With Atopic Eczema; a Phase IIa, Single-center, Randomized, Observer-blind Study
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: K201|DRUG: K201
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose:
Clinical trial: Evaluation of Efficacy and Safety of a Single Dose of Exa-cel in Participants With Severe Sickle Cell Disease, βS/βC Genotype
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: Exa-cel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Hybrid Medical Care Model in the Rheumatoid Arthritis Patient-reported-outcomes Measures
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Telehealth
Interventions: OTHER: Face-to-face medical visits|OTHER: Alternating face-to-face medical visits and video medical consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
Status: RECRUITING
Conditions: Pompe Disease (Late-onset)
Interventions: BIOLOGICAL: Cipaglucosidase Alfa|DRUG: Miglustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer
Interventions: PROCEDURE: Liver preparation before major hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Study of Epigallocatechin-3-gallate in Patients With Esophageal Squamous Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Dysphagia, Esophageal|Epigallocatechin Gallate
Interventions: OTHER: Epigallocatechin-3-gallate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Levels, Metabolism and Excretion, and Absolute Bioavailability of BMS-986365 in Healthy Male Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986365|DRUG: [14C] BMS-986365|DRUG: [14C] BMS-986409 + BMS-986410|DRUG: [14C] BMS-986410 + BMS-986409
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Multiple-Vaccine to Treat Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: CDCA1，URLC10，KIF20A，DEPDC1 and MPHOSPH1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Study of PRV-6527 in Subjects With Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: PRV-6527|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternation in the Human Microbiome With Commonly Used Topical Medications
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Desonide 0.05%|DRUG: Ketoconazole 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of Synchronized and Non-invasive Ventilation ("NeuroPAP") in Preterm Newborns
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: NeuroBox to deliver the NeuroPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Lens Implant Registry Study
Status: RECRUITING
Conditions: Intraocular Lens Complication|Intraocular Lens Rotation|Intraocular Lens Associated Postoperative Inflammation|Lens Opacities
Interventions: DEVICE: Intraocular lens Implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identification of Individual Histological and Blood Markers in Patients With Recurrent or Metastatic Upper Aerodigestive Tract Squamous Cell Carcinoma in Response to Immunotherapies
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Oropharynx
Interventions: PROCEDURE: Tumor Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The French Cohort and Biobank of Devic's Neuromyelitis Optica and Related Neurological Disorders (NMOSD) (NOMADMUS)
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorders|Neuromyelitis Optica Spectrum Related Disorders
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of New Therapeutic Schedules in Naive Hepatitis C Virus (HCV) Patients Infected With Genotype 3 (HCV-3)
Status: COMPLETED
Conditions: Chronic Hepatitis
Interventions: DRUG: Peg Interferon alpha2b + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
Status: COMPLETED
Conditions: Opioid-Induced Constipation (OIC)
Interventions: DRUG: NKTR-118|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Baclofen|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine PF-07853578 and How it Acts in the Bodies of Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-07853578|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics Study of CKD-11101 and NESP After IV Administration in Health Male Volunteers
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: NESP 60μg|DRUG: CKD-11101 60μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome
Status: UNKNOWN
Conditions: Antiphospholipid Syndrome|Endothelial Dysfunction|Hyperuricemia|Gout|Metabolic Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of Acupuncture on Hand Pain, Functional Deficits and Health Related Quality of Life in Patients With Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Acupuncture
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Status: UNKNOWN
Conditions: Stable Angina|Unstable Angina|Myocardial Infarction|Unheralded Coronary Heart Disease Death|Heart Failure|Cardiac Arrest|Transient Ischaemic Attack|Ischemic Stroke|Subarachnoid Hemorrhage|Intracerebral Hemorrhage|Peripheral Arterial Disease|Abdominal Aortic Aneurysm|Atrial Fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PD-1 Inhibitors With or Without Radiation in Advanced Melanoma
Status: NOT_YET_RECRUITING
Conditions: the Efficacy and Safety of PD-1 Inhibitors With or Without Radiotherapy in Patients With Advanced Melanoma
Interventions: RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Different Anticoagulant Therapy on Hemorrhage and Coagulation After Thoracic Surgery
Status: COMPLETED
Conditions: Lung Neoplasms|Esophageal Neoplasms|Venous Thromboembolism
Interventions: DRUG: Fondaparinux|DRUG: Nadroparin Calcium|DRUG: Nadroparin Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Two-Week Study of Clinical Safety and Saliva Flow Quantification
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Colgate Cavity Protection Toothpaste|OTHER: LISTERINE Cool Mint Antiseptic Mouthwash|OTHER: Listerine Advanced Gum Alcohol|OTHER: Listerine Advanced Gum Zero|OTHER: LISTERINE ULTRACLEAN Tartar Control Antiseptic Mouthwash Cool Mint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Infuse® Bone Graft With Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of Multi-Level Degenerative Lumbosacral Spinal Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Multi-Level Degenerative Lumbosacral Spinal Conditions
Interventions: DEVICE: Infuse Bone Graft|DEVICE: Medtronic DBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptive (OC) Estrogen Dose and Breast Proliferation
Status: UNKNOWN
Conditions: Oral Contraceptive
Interventions: DRUG: Oral Contraceptive: Ortho-Novum® 1/35|DRUG: Oral Contraceptive: Ovcon® 35|DRUG: Oral Contraceptive: Microgestin Fe® 1/20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SO+IUI After Operative Laparoscopy in Patients With Advanced Stage Endometriosis
Status: WITHDRAWN
Conditions: Endometriosis|Infertility
Interventions: DRUG: Supraovulation clomiphene citrate|BEHAVIORAL: Timed intercourse|PROCEDURE: Intrauterine Insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variability in the Measurement of WBCT Between Blood Drawn From Indwelling Catheters and Direct Venipuncture
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Blood drawn from indwelling catheters versus direct venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Yogurt Containing BB12 on Children's Health and Child Care Absenteeism
Status: COMPLETED
Conditions: Children's Health and Growth|Childcare Absenteeism
Interventions: OTHER: Yogurt drink with probiotic bacteria BB12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study To Investigate The Safety And Toleration Of Multiple Oral Doses Of PF-03654764 In Combination With Fexofenadine In Healthy Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: PF-03654764 2.5mg plus fexofenadine 60mg|DRUG: PF-03654764 5mg plus fexofenadine 60mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Linagliptin in Elderly Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: linagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Vestibular Rehabilitation in Patients With Dizziness and Balance Disorders After Sport Concussion
Status: TERMINATED
Conditions: Brain Concussion
Interventions: OTHER: Early Vestibular Rehabilitation|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Nurse-led Intervention to Extend the HIV Treatment Cascade for Cardiovascular Disease Prevention
Status: COMPLETED
Conditions: HIV/AIDS|Hypertension|Hyperlipidemias
Interventions: OTHER: Multi-component intervention|OTHER: General prevention education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fermented Food-Supplemented Diet in Ulcerative Colitis
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Diet Modification|Ulcerative Colitis
Interventions: OTHER: Fermented Food-supplemented Diet|OTHER: Regular Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Derma Pen as Treatment of Gingivitis Induced by Orthodontics
Status: RECRUITING
Conditions: Gingivitis|Orthodontic Appliance Complication
Interventions: PROCEDURE: mechanical periodontal treatment|DEVICE: Derma pen with topical ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Inspiratory Muscle Training Improve Functional Capacity in Subjects With Obstructive Sleep Apnea?
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Powerbreathe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Rheumatoid Arthritis With Ongoing Treatment With Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ACZ885|DRUG: ACZ885
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Mesenchymal Stem Cells And Physical Therapy for MS Treatment
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Umbilical cord derived Mesenchymal Stem Cells|OTHER: Supervised physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Refractory Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Axatilimab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Paclitaxel|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Facilitated Antegrade Steering Technique in Chronic Total Occlusions
Status: COMPLETED
Conditions: Chronic Total Occlusion
Interventions: DEVICE: CTO Crossing and Percutaneous transluminal angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gentuximab + Paclitaxel in Patients With Advanced Gastric or Gastroesophageal Junction Cancer
Status: UNKNOWN
Conditions: Advanced Gastric or Gastroesophageal Junction Cancer
Interventions: DRUG: Gentuximab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AK112 Combined With PARP Inhibitor in the Treatment of Recurrent Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Neoplasms|Recurrent Ovarian Carcinoma|Relapsed Ovarian Cancer|Ovarian Cancer
Interventions: DRUG: AK112 low dose|DRUG: AK112 medium dose|DRUG: AK112 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine
Status: COMPLETED
Conditions: Hepatic Impairment|Normal Hepatic Function
Interventions: DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Short Hydration Method for Cisplatin Administration Compared With Conventional Hydration
Status: RECRUITING
Conditions: Renal Insufficiency|Cis-Platinum Nephropathy
Interventions: PROCEDURE: short hydration|PROCEDURE: conventional hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PM8002 in Combination With Chemotherapy as First Line Therapy in Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: PM8002|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Valproate and Doxorubicin in Malignant Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: DRUG: Valproate plus doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Micro-bypass Stents or Selective Laser Trabeculoplasty
Status: COMPLETED
Conditions: Open-angle Glaucoma
Interventions: DEVICE: iStent|OTHER: SLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Acceptability of Psychological Treatments for Obsessive-compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: OTHER: Cognitive therapy|BEHAVIORAL: Exposure and Response Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on Constipation, and Intestinal Microflora in Children With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DRUG: Magnesium Oxide|DRUG: MIYAIRI-BM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Length of Uteroovarian Ligament and the Risk of Ovarian Torsion
Status: UNKNOWN
Conditions: Ovarian Torsion
Interventions: PROCEDURE: Measure of uteroovarian ligament length during gynecological surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Low dose MDMA|DRUG: Medium dose MDMA|DRUG: Full dose MDMA|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease
Status: COMPLETED
Conditions: Systemic Sclerosis|Scleroderma|Interstitial Lung Disease
Interventions: DRUG: Mycophenolate mofetil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gluconate Versus Povidone Iodine at Cesarean Delivery: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Pregnancy|Cesarean Section
Interventions: OTHER: Chlorhexidine Gluconate|OTHER: Povidone Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Lymphocytic Leukemia|AML, Adult|CLL|CLL, Relapsed|CLL, Refractory
Interventions: DRUG: Pitavastatin|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening
Status: ENROLLING_BY_INVITATION
Conditions: Hpv|HPV 16 Infection|HPV Infection|High Risk HPV
Interventions: DEVICE: Teal Wand Self-Collection Device Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Total Lymphoid Irradiation and Anti-Thymocyte Globulin in the Allogeneic Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: HEMATOLOGIC MALIGNANCIES
Interventions: OTHER: TOTAL LYMPHOID IRRADIATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth and Tolerance of Infants Fed Infant Formulas
Status: COMPLETED
Conditions: Growth and Tolerance
Interventions: OTHER: Control Formula|OTHER: Experimental Formula 1|OTHER: Experimental Formula 2|OTHER: Human Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Oral Immunotherapy in Cow's Milk Allergy (CMA) in Children : "Petit Lait" Study
Status: COMPLETED
Conditions: Cow's Milk Allergy
Interventions: OTHER: raw milk|OTHER: Heated milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, and Varicella (MMRV) Vaccine Made With an Alternative Manufacturing Process (AMP)(V221-027)
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: MMRV (AMP)|BIOLOGICAL: MMRV (2006 process)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NNITS-Nitazoxanide for Norovirus in Transplant Patients Study
Status: COMPLETED
Conditions: Gastroenteritis Norovirus
Interventions: DRUG: Nitazoxanide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Etoposide and Celecoxib in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: celecoxib|DRUG: etoposide|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cardio Protective Properties of a Yogurt Enriched With Bioactive Lipids of Olive Oil Products
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: OTHER: Enriched Yogurt|OTHER: Plain Yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Obturator Nerve Block for Anterior Cruciate Ligament Reconstruction (ACL)
Status: COMPLETED
Conditions: Anterior Cruciate Ligament|Surgery
Interventions: OTHER: Sciatic, femoral, obturator nerve blocks|OTHER: Sciatic nerve block, posterior lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in the Treatment of Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DEVICE: Anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab & Celecoxib for Metastatic Colorectal Cancer or Colorectal Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: celecoxib|GENETIC: proteomic profiling|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir 1% vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Real Life Study on Iron Isomaltoside 1000 in the Treatment of ID in CKD, Heart Failure, ObGyn, IBD, Cancer and Elective Surgery (Real-CHOICE).
Status: COMPLETED
Conditions: Iron-Deficiency Anemia|Iron-Deficiency
Interventions: DRUG: Iron isomaltoside 1000
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown
Status: NOT_YET_RECRUITING
Conditions: Carious Teeth
Interventions: PROCEDURE: Prefabricated pediatric zirconia crown group|PROCEDURE: Prefabricated stainless steel crown group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and SBRT in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Erlotinib|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Liposomal Doxorubicin as a Induction Therapy for Lymphoma Induced Hemophagocytic Lymphohistiocytosis.
Status: UNKNOWN
Conditions: Hemophagocytic Lymphohistiocytosis
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Etoposide|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Intravenous Fluids During Labor
Status: COMPLETED
Conditions: Ketosis
Interventions: OTHER: D5 Lactated Ringer's Solution (D5LR)|OTHER: Lactated Ringer's Solution (LR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal|Periodontitis
Interventions: PROCEDURE: Phase 1 periodontal therapy|DRUG: Bisphosphonate therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC