pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
Status: UNKNOWN
Conditions: Compartment Syndrome
Interventions: DEVICE: Compartment Monitoring System (CMS)|DEVICE: Compartment Monitoring System with Active Fluid Removal|DEVICE: Compartment Monitoring System without fluid removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: St. John's Wort And Kava In The Treatment Of Major Depressive Disorder With Comorbid Anxiety
Status: COMPLETED
Conditions: Depressive Disorder, Major|Anxiety Disorders
Interventions: DRUG: Herbal medicine (St. John's wort and Kava)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Sunobinop|DRUG: Placebo to match sunobinop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing AIN457 to Placebo in Subjects With a Diagnosis of Moderate to Severe Stable Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: AIN457|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PemVin vs Vin in Previously Treated Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: Pemetrexed + Vinorelbine|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Brain Tumor|Recurring Glioblastoma
Interventions: BIOLOGICAL: delta-24-RGD adenovirus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Tissue Engineered Skin Substitute|DEVICE: Offloading|PROCEDURE: Amnionic Membrane Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Oral LT3 Therapy for Heart Failure - HFrEF
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction|Low Triiodothyronine Syndrome
Interventions: DRUG: liothyronine or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ISIS 14803, peginterferon alfa, ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Cold and Compression Therapy With Total Knee Replacement Patients
Status: UNKNOWN
Conditions: Osteoarthritis|Total Knee Arthroplasty
Interventions: DEVICE: Game Ready Injury Treatment System (CoolSystems Inc.)|OTHER: Ice with compressive bandages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Resected Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5-fluorouracil|DRUG: leucovorin calcium|DRUG: tegafur|DRUG: uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Experimental: ALBA|BEHAVIORAL: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coenzyme Q10 in Adult-Onset Ataxia
Status: COMPLETED
Conditions: Sporadic Ataxia
Interventions: DRUG: Placebo (sugar pill)|DRUG: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction|Fibrinolysis|P2Y12 Inhibitor
Interventions: DRUG: Ticagrelor 180mg loading dose and 90mg bid maintenance dose|DRUG: Clopidogrel 600mg loading dose and 150mg maintenance dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protect II, A Prospective, Multicenter Randomized Controlled Trial
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: IMPLELLA LP 2.5|DEVICE: IABP Intra-aortic balloon pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: topotecan hydrochloride|DRUG: Isotretinoin|PROCEDURE: Surgery|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H2158 Reference Formulation|DRUG: ABI-H2158 Test Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Microbiome Study of Appendiceal Cancer
Status: RECRUITING
Conditions: Pseudomyxoma Peritonei|Appendiceal Neoplasm|Cancer, Appendiceal
Interventions: OTHER: Bio-specimen collection|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stressors and Recovery Regulation on the Super-compensation Effect
Status: RECRUITING
Conditions: Exercise Overtraining|Stressor, Psychological
Interventions: OTHER: High-intensity intensive training|OTHER: Taper
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Trial of Hepatitis C Self-Testing in the Hands of Untrained Lay Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C
Interventions: DEVICE: INSTI HCV Self Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Fludarabine monophosphate|DRUG: Rituximab|DRUG: Busulfan|DRUG: ATG|DRUG: Cyclophosphamide|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Assessment of Respiratory Function, Inflammation and Bronchial Reshuffle Among Newborns Screened for Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: assessment of lung function
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: erlotinib hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Second-line Endocrine Treatment Followed by Capecitabine Versus Capecitabine Followed by Endocrine Treatment in Patients With Metastatic ER Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: hormonal treatment (tamoxifen, exemestane, anastrozole or letrozole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Propranolol Hydrochloride Extended-Release Capsules 160 mg and Inderal® LA Capsules 160 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Propranolol Hydrochloride Extended-Release Capsules 160 mg|DRUG: Inderal® LA Capsules 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: Mavacamten|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Anti-fungal Effect of Miconazol Versus Miconazol-Loaded Chitosan Nanoparticles
Status: COMPLETED
Conditions: Oral Thrush
Interventions: DRUG: Chitosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Xenon Functional Lung Imaging in COPD Patients Undergoing Targeted Lung Denervation
Status: NOT_YET_RECRUITING
Conditions: COPD
Interventions: DIAGNOSTIC_TEST: Functional imaging of the lungs using MagniXene (hyperpolarized xenon-129) MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema
Status: COMPLETED
Conditions: Breast Cancer|Head and Neck Cancer|Lymphedema
Interventions: OTHER: Acupuncture and moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Montelukast in Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Montelukast/ Singulair|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Relapsing Chronic Myelogenous Leukemia|Secondary Myelodysplastic Syndromes
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing Profile of Titanium Dental Implants Placed in Patients With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Dental Implants
Interventions: PROCEDURE: Implant placement|PROCEDURE: Implants surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Adverse Environment Factors, Family Functioning and Parental Psychopathology in the Response to Treatment With Methylphenidate in Children and Adolescents With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy of Nitric Oxide in Stroke (ENOS) Trial
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Transdermal glyceryl trinitrate patch|DRUG: Pre-stroke antihypertensives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors
Status: RECRUITING
Conditions: The Aim of the Study is to Evaluate the Efficacy of Photodynamic Therapy as an|Adjuvant Therapy on the Clinical Outcome of Patients With Desmoid Tumors After|Surgical Resection
Interventions: DRUG: 5-AMINOLEVULINIC ACID (5-ALA), is a non fluorescent prodrug.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SMART CART Study: Health Information Technology
Status: COMPLETED
Conditions: Leukemia, Acute|Leukemia, Lymphoblastic
Interventions: BEHAVIORAL: Education information system|OTHER: Activity monitor|OTHER: Interview|OTHER: Survey Administration|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hypofractionated Stereotactic Boost in Prostate Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: RADIATION: First part of treatment : Conformal irradiation|PROCEDURE: Fiducials placement|RADIATION: Second part : hypofractionated stereotactic boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: PROCEDURE: Biopsy|DRUG: Part A: Safusidenib Erbumine|PROCEDURE: Surgery (maximal resection)|DRUG: Part B: Safusidenib Erbumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder|Bipolar Disorder Type 1
Interventions: DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Ketones
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody for Third-line Treatment in mCRC
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: SBRT, Fruquintinib, Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Basal Cell Nevus Syndrome
Interventions: BIOLOGICAL: ASN-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Game Profile-based Training and Small-sided Games Among Football Players
Status: RECRUITING
Conditions: Physical Endurance|Muscle Strength|Functional Performance
Interventions: OTHER: Game Profile-based training Group|OTHER: Small-sided games Group|OTHER: Combined training Group with both Game Profile-based training and Small-sided Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Studying Fibroblast Activity in Patients With Localized Pancreatic Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Safety of Intranasal Glulisine in Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome
Interventions: DRUG: Insulin glulisine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Interleukin-2 in Treating Women With Stage IV, Recurrent, or Progressive Breast or Ovarian Cancer
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: p53 peptide vaccine|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Hot and Cold Biopsy Forceps in the Diagnosis of Endobronchial Lesions
Status: COMPLETED
Conditions: Endobronchial Growth|Lung Cancer
Interventions: DEVICE: Hot biopsy forceps|DEVICE: Cold biopsy forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Thoracic Fluid Content During Hypervolemic Hemodilution
Status: COMPLETED
Conditions: Pulmonary Edema
Interventions: DEVICE: Thoracic fluid content estimation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Spine Radiosurgery for Symptomatic Metastatic Neoplasms
Status: RECRUITING
Conditions: Metastatic Neoplasm to the Spine|Metastatic Neoplasm
Interventions: RADIATION: Conventional external beam radiation therapy dose (EBRT)|RADIATION: Spine radiosurgery/stereotactic body radiation therapy standard dose|RADIATION: Spine radiosurgery/stereotactic body radiation therapy high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer|Cancer of the Rectum|Colorectal Cancer
Interventions: DRUG: 5-Fluorouracil|DRUG: Bevacizumab|PROCEDURE: Radiation Therapy|DRUG: Oxaliplatin|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Randomized Controlled Trial to Compare the Outcome of Conservative Triple Target Treatment With EMG-Biofeedback in Chronic Obstipation
Status: UNKNOWN
Conditions: Chronic Obstipation
Interventions: DEVICE: Combination of EMG-biofeedback plus EMG-triggered AM-MF-stimulation|DEVICE: EMG-biofeedback alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between Colchicine and Ketoconazole
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine|DRUG: Ketoconazole|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Potency Statins and Acute Kidney Injury
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin (≥10 mg)|DRUG: Atorvastatin (≥20 mg)|DRUG: Simvastatin (≥40 mg)|DRUG: Fluvastatin|DRUG: Pravastatin|DRUG: Lovastatin|DRUG: Atorvastatin (<20mg)|DRUG: Simvastatin (<40 mg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oxytocin and Cognitive Behavioral Therapy in Drug Dependence
Status: TERMINATED
Conditions: Drug Dependence
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Intranasal Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)
Status: COMPLETED
Conditions: Acute Hepatic Porphyria|Acute Intermittent Porphyria|Porphyria, Acute Intermittent|Acute Porphyria|Hereditary Coproporphyria (HCP)|Variegate Porphyria (VP)|ALA Dehydratase Deficient Porphyria (ADP)
Interventions: DRUG: Givosiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Procedural Advantages of a Novel Drug-Eluting Coronary Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Synergy Stent|DEVICE: Currently common drug-eluting stent (DES)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: multiSENSory Stimulation to tArgeT Sensory Loss and chronIc Pain in neurOpathic patieNts
Status: UNKNOWN
Conditions: Neuropathy|Neuropathy, Painful|Sensory Neuropathy|Diabetic Neuropathies|Amputation
Interventions: COMBINATION_PRODUCT: VR+TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasopressor Prophylaxis After Spinal Anesthesia
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: Norepinephrine 0.05 mcg /Kg/min|DRUG: Norepinephrine 0.1 mcg /Kg/min|DRUG: Norepinephrine 0.15 mcg /Kg/min|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery
Status: RECRUITING
Conditions: Sleep Apnea
Interventions: DRUG: Danavorexton|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Infrahepatic Inferior Vena Cava Clamping Versus Selective Hepatic Vascular Exclusion Involving the Portal Triad Clamping
Status: UNKNOWN
Conditions: Liver Neoplasms|Liver Cirrhosis
Interventions: PROCEDURE: Infrahepatic inferior vena cava clamping|PROCEDURE: Selective hepatic vascular exclusion|PROCEDURE: Portal triad clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Lifestyle Pregnancy and Post Pregnancy Intervention for Overweight Women With Gestational Diabetes Mellitus
Status: UNKNOWN
Conditions: Weight Loss|Gestational Diabetes
Interventions: OTHER: PAIGE2 lifestyle intervention|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Musical Engagement on Medical Resident Well-being
Status: NOT_YET_RECRUITING
Conditions: Burnout|Student Burnout|Physical Disability|Resident Doctor|Music Therapy|Music|Stress|Wellness, Psychological
Interventions: BEHAVIORAL: Musical engagement sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Contribution in the Prevention of Perioperative Bleeding in Thoracic Surgery
Status: COMPLETED
Conditions: Bleeding
Interventions: DRUG: Tranexamic acid injection|DRUG: SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of NSAID Patch Given in Monotherapy and NSAID Patch in Combination With Transcutaneous Electric Nerve Stimulation, Heating Pad, or Topical Capsaicin in the Treatment of Patients With Myofascial Pain Syndrome of the Upper Trapezius: A Pilot Study
Status: COMPLETED
Conditions: Myofascial Pain Syndrome of the Upper Trapezius
Interventions: DRUG: NSAID patch|DRUG: NSAID patch + transcutaneous electric nerve stimulation|DRUG: NSAID patch + heating pad|DRUG: NSAID patch + topical capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking
Interventions: OTHER: Ariva Silver Wintergreen|OTHER: Placebo Wintergreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparison of Two Peripheral Inserted Intravenous Catheters
Status: COMPLETED
Conditions: Catheter-Related Infections|Catheter Related Complication
Interventions: DEVICE: Midline catheter|DEVICE: PICC-line catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Dornase alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurobiologic, Immunologic, and Rheumatologic Markers in Youth With PANS
Status: RECRUITING
Conditions: Pediatric Acute-Onset Neuropsychiatric Syndrome|Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections|PANS|PANDAS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CORE: Capecitabine, Oxaliplatin, Radiotherapy and Excision
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: Oxaliplatin, capecitabine, radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remote Ischemic Preconditioning on Postoperative Cognitive Dysfunction in Total Knee Replacement
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BenRalizumab Effect on Airway Remodeling in Severe asTHma
Status: RECRUITING
Conditions: Asthma; Eosinophilic|Airway Remodeling
Interventions: DRUG: Benralizumab 30 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis Bullosa
Status: COMPLETED
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: Gene-modified autologous fibroblasts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
Status: RECRUITING
Conditions: High Risk Cancer|Pancreatic Cancer
Interventions: DRUG: Cohort A: Patients at high risk of developing pancreatic cancer.|DRUG: Cohort B: Patients must have evidence of a pancreatic cystic neoplasm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of the Modified Sleeper-Stretch on the Elasticity of the Posterior and Posteroinferior Glenohumeral Capsule
Status: NOT_YET_RECRUITING
Conditions: Shoulder Pain|Shoulder Pain Chronic
Interventions: OTHER: Modified Sleeper-Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARISE: Evaluation of the GORE® Ascending Stent Graft in the Treatment of DeBakey Type I/II Aortic Dissection
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Dissection
Interventions: DEVICE: GORE® Ascending Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cephalic Phase Responses to Nutritive and Non-Nutritive Sweeteners
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre Diabetes
Interventions: OTHER: No Oral Stimulation|OTHER: Oral water stimulation|OTHER: Oral Salt Stimulation|OTHER: Oral Sucralose Stimulation|OTHER: Oral Sucrose stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Baricitinib Plus Glucocorticoid for Eosinophilia in IgG4-RD
Status: RECRUITING
Conditions: IgG4-related Disease With Eosinophilia
Interventions: DRUG: Prednisolone|DRUG: Baricitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole-Body Vibration Versus Kineso Tape on Nerve Conduction in Patient With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: OTHER: Traditional balance exercise|OTHER: Resistance exercise|OTHER: Whole-body vibration (WBV)|OTHER: Kineso tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Dense Induction/Neoadjuvant Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: cisplatin|DRUG: Docetaxel|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omalizumab (Xolair) in Treatment of Patients With AERD and Allergy Asthma
Status: UNKNOWN
Conditions: Asthma|Allergic Rhinitis
Interventions: DRUG: omalizumab (Xolair)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Gastric Cancer, Colorectal Cancer and Bladder Cancer Based on Liquid Biopsy
Status: UNKNOWN
Conditions: Gastric Cancer|Colorectal Cancer|Bladder Cancer
Interventions: DIAGNOSTIC_TEST: DNA extraction of samples and high-throughput sequencing of small panels|DIAGNOSTIC_TEST: DNA extraction of samples and high-throughput sequencing of small panels|DIAGNOSTIC_TEST: DNA extraction of samples and high-throughput sequencing of small panels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Probiotics on Iron Status During Pregnancy
Status: COMPLETED
Conditions: Prevention of Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of Consistency by Finger Stick Blood Glucose or Venous Blood Glucose of Flash Glucose Monitoring in Different Infiltration Time
Status: UNKNOWN
Conditions: Type 2 Diabetes|Flash Glucose Monitoring|Conscience
Interventions: DEVICE: FGM infiltration 1 hour group|DEVICE: FGM infiltration 6-hour group|DEVICE: FGM infiltration 12-hour group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of TAK-861 in Participants With Narcolepsy Type 2
Status: COMPLETED
Conditions: Narcolepsy Type 2
Interventions: DRUG: TAK-861|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Urinary Continence of Female POPRC and OIN
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder Neoplasms|Woman|Sexual Dysfunction, Physiological|Treatment Outcome|Urinary Incontinence
Interventions: PROCEDURE: POPRC+OIN|PROCEDURE: SRC+OIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shorter Radiation Schedule for the Treatment of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: 5250 cGy/20 fractions over 28 days|PROCEDURE: 6600 cGy/33 fractions over 45 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705|DRUG: GW642444|DRUG: GSK233705 and GW642444|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Enteral Colostrum on Intestinal Permeability in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: Colostrum|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Status: COMPLETED
Conditions: Articular Cartilage Defects of Ankle Joint
Interventions: PROCEDURE: Chondron(autologous chondrocyte) Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dark Chocolate and Exercise Performance in Hypoxia
Status: COMPLETED
Conditions: Hypoxia
Interventions: DIETARY_SUPPLEMENT: Dark chocolate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of NPH Insulin, Insulin Detemir and Insulin Glargine on GH-IGF-IGFBP Axis
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: NPH|DRUG: Detemir|DRUG: Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN
Status: TERMINATED
Conditions: Burning Pain|Impaired Balance|Malignant Ovarian Neoplasm|Numbness|Peripheral Neuropathy|Pain, Acute|Tingling
Interventions: DIAGNOSTIC_TEST: Diode Laser fiber type Selective Stimulator (DLss)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Hexacapron in Upper Gastrointestinal Bleeding
Status: UNKNOWN
Conditions: Upper Gastrointestinal Bleeding|Hexacapron|Hemostasis|Rebleeding|Mortality
Interventions: DRUG: Hexacapron( Tranexamic acid)|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: 1-methyl-d-tryptophan|DRUG: docetaxel|OTHER: diagnostic laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Online Real-time Home CPR Training Program
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Cardiopulmonary Arrest|Education
Interventions: OTHER: Real-time home CPR training|OTHER: Conventional CPR training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Routine Calcium for Preventing Hypocalcemia
Status: COMPLETED
Conditions: Thyroid Neoplasm
Interventions: DRUG: Calcium Carbonate 1500 Mg with Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicentered Prospective Randomized Controlled Trial For Solid Pancreatic Lesions
Status: RECRUITING
Conditions: Pancreas Neoplasm
Interventions: PROCEDURE: Endoscopic Ultrasound -Guided Fine Needle Biopsy|PROCEDURE: Contrast-Enhanced Harmonic Endoscopic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfemoral Versus Transradial Partial Splenic Artery Embolization in Patients With Hypersplenism
Status: COMPLETED
Conditions: Hypersplenism
Interventions: PROCEDURE: partial splenic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SurmodiCs Pounce Venous THrOMbectomy System Post Market Clinical Follow Up Study
Status: NOT_YET_RECRUITING
Conditions: Peripheral Vascular Occlusive Disease
Interventions: DEVICE: Pounce Venous Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: radiation treatment and surgery|PROCEDURE: radiation alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Almond Consumption and Glycemia
Status: COMPLETED
Conditions: Glucose Intolerance|Appetite Disorders|Glucose Metabolism Disorders (Including Diabetes Mellitus)|Lipid Metabolism Disorder
Interventions: OTHER: Almonds|OTHER: Control (no nuts)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Hypercholesteremia
Interventions: DRUG: Gemcabene 300 mg|DRUG: Gemcabene 900 mg|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Evaluation of the Impact of Pre-operative Device on the Personal Experience of Brain Awake Surgery
Status: UNKNOWN
Conditions: Brain Awake Surgery
Interventions: DEVICE: preoperative adequate explanations about awake surgery|OTHER: no preoperative explanation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Mean Arterial Pressure (MAP) and Renal Perfusion: Evaluation of Critically Ill Patients With Normal Creatinine or Reduced Renal Function
Status: WITHDRAWN
Conditions: Kidney Failure, Acute
Interventions: PROCEDURE: controlling the MAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinect-based Upper Limb Rehabilitation System in Stroke Patients
Status: TERMINATED
Conditions: Stroke|Hemiplegia|Virtual Rehabilitation
Interventions: PROCEDURE: Kinect-based rehabilitation plus occupational therapy|OTHER: sham virtual rehabilitation education plus occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder|Alzheimer Disease|FTD
Interventions: DIAGNOSTIC_TEST: blood sample taken
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients
Status: RECRUITING
Conditions: Chronic Kidney Failure in Children and Young Adults
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double vs Single Intrauterine Insemination in Male Factor Infertility
Status: RECRUITING
Conditions: Male Factor Infertility
Interventions: PROCEDURE: intrauterine insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone Plus Metformin in Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Metformin plus Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Comparison of Universal Adhesives in Terms of Different Application Modes on the Restoration of NCCLs
Status: COMPLETED
Conditions: Tooth Wear
Interventions: DEVICE: Gluma Universal|DEVICE: All Bond Universal|DRUG: Single Bond2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Status: COMPLETED
Conditions: Pregnant Women
Interventions: DRUG: Hyperbaric prilocaine 2%|DRUG: Hyperbaric prilocaine 2%|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test MK-0941 in Adults With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0941-018)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-0941|DRUG: Placebo|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Status: COMPLETED
Conditions: Inhalation Anesthesia|Lung Injury
Interventions: DRUG: Sevoflurane|DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Baerveldt 350 vs Ahmed ClearPath 250 for the Treatment of Glaucoma
Status: RECRUITING
Conditions: Glaucoma
Interventions: DEVICE: Baerveldt 350 vs. Ahmed ClearPath 250 tube shunt implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Hi-tACS on Cognitive Function in Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: high-frequency transcranial alternating current stimulation|DEVICE: sham high-frequency transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Silent Myocardial Ischemia (MSSMI)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Myocardial Ischemia|Heart Diseases|Myocardial Infarction|Angina, Unstable|Arrhythmia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis (NASH)
Interventions: DRUG: SEL|BIOLOGICAL: SIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tapentadol Versus Tramadol Analgesia Post Cardiac Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Surgery|Pain, Postoperative|Pain, Acute|Pain, Chronic|Pain, Procedural|Pain, Neuropathic|Analgesia
Interventions: DRUG: Group tapentadol 50 mg|DRUG: group tapentadol 75 mg|DRUG: group tramadol 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION