pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Scalable Weight Control Intervention for Adolescents
Status: UNKNOWN
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Behavioral weight control|BEHAVIORAL: Group-based physical activity|BEHAVIORAL: Group-based incentives|BEHAVIORAL: Parent-based incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Skills Group Training ("KONTAKT") for Children and Adolescent With High-functioning Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorder (ASD)|Attention Deficit Hyperactivity Disorder (ADHD)|Anxiety|Depression
Interventions: BEHAVIORAL: Social skills group training, KONTAKT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion
Status: TERMINATED
Conditions: Anesthesia|Urethral Obstruction
Interventions: DRUG: Placebo|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Faba Bean Rich Bread on Iron Status, Postprandial Lipaemia and Satiety
Status: NOT_YET_RECRUITING
Conditions: Anemia, Iron Deficiency|Cardiometabolic Disease|Low Iron Stores
Interventions: OTHER: Raising the Pulse faba bean-enriched bread|OTHER: Conventional White Bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Administration of Allogenic Red Blood Cells Loaded L-asparaginase in Cases of Relapse of Acute Lymphoblastic Leukaemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: GRASPA|BIOLOGICAL: GRASPA|BIOLOGICAL: GRASPA|DRUG: native L asparaginase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients
Status: UNKNOWN
Conditions: Neurokinin 1 Receptor, Substance P, Respiratory Illness, Inflammation, Covid-19, Coronavirus
Interventions: DRUG: NK-1R antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Microcirculation Indexes and Hemodynamic Indexes to Guide Resuscitation in Patients With Septic Shock
Status: UNKNOWN
Conditions: Sepsis
Interventions: DEVICE: sublingual microcirculation,|DEVICE: hemodynamic monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Arformoterol tartrate|DRUG: Placebo: Normal Saline|OTHER: Treadmill Exercise|OTHER: Cycle Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine Gel and Cold Lidocaine Gel on Pain in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Status: COMPLETED
Conditions: Prostate Cancer XXX|TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Interventions: OTHER: LIDOCAINE GEL|OTHER: COLD LIDOCAINE GEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 68Ga-OPS202 Study for Diagnostic Imaging of GEP NET
Status: COMPLETED
Conditions: Gastroenteropancreatic Neuroendocrine Tumors
Interventions: DRUG: satoreotide trizoxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Status: RECRUITING
Conditions: Intracerebral Hemorrhage|Atrial Fibrillation
Interventions: DRUG: Apixaban|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Plasma Injections Plus Exercise for Patellar Tendinopathy
Status: TERMINATED
Conditions: Patellar Tendinopathy
Interventions: BIOLOGICAL: Platelet Rich Plasma (PRP)|OTHER: Saline + exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Replacement|Genicular Nerve Block|Opioid Use
Interventions: DRUG: Bupivacaine Injection|DRUG: Dexamethasone injection|DRUG: Fentanyl|DRUG: Mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase III Study to Compare Perioperative Chemotherapy of Oxaliplatin Combined With S-1(SOX) Versus SOX or Oxaliplatin With Capecitabine (XELOX) as Post-operative Chemotherapy in Locally Advanced Gastric Adenocarcinoma With D2 Dissection
Status: UNKNOWN
Conditions: Advanced Gastric Carcinoma
Interventions: DRUG: Oxaliplatin capecitabine|DRUG: Oxaliplatin S-1|DRUG: Oxaliplatin S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Brain Stimulation for Medication-Resistant Auditory Hallucinations in Schizophrenia Patients
Status: WITHDRAWN
Conditions: Auditory Hallucinations|Schizophrenia
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving SCI Rehabilitation Interventions by Retraining the Brain
Status: RECRUITING
Conditions: Cervical Spinal Cord Injruy
Interventions: DEVICE: Active tDCS + task oriented practice|DEVICE: Sham tDCS + task oriented practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Derived Mesenchymal Stromal Cells For The Treatment of Severe Steroid-resistant Graft Versus Host Disease
Status: UNKNOWN
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: UMBILICAL CORD DERIVED MESENCHYMAL STROMAL CELLS (UC-MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of MBR + Suture Tape and Anatomic Reconstruction for CLAI in GJL Cases: A Prospective Cohort Study
Status: RECRUITING
Conditions: Ankle Sprains|Hypermobility Syndrome
Interventions: PROCEDURE: Modified Broström + Suture tape augmentation operation|PROCEDURE: Anatomic reconstruction operation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: In-patient COVID-19 Study of Intranasal Foralumab
Status: WITHDRAWN
Conditions: Covid19|COVID-19 Lower Respiratory Infection|COVID-19 Respiratory Infection
Interventions: DRUG: Foralumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Interventions in Patients With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Carpal Tunnel Syndrome Bilateral
Interventions: BEHAVIORAL: stretching physiotherapy|BEHAVIORAL: Myofascial therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Darbepoetin Alfa in the Treatment of Renal Anemia
Status: COMPLETED
Conditions: Anemia|Kidney Failure, Chronic|Peritoneal Dialysis, Continuous Ambulatory
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Myofascial Release Techniques on Balance in Young Adults With Pes Planus
Status: COMPLETED
Conditions: Flat Foot
Interventions: OTHER: Graston|OTHER: Percussive massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
Status: COMPLETED
Conditions: Infant, Very Low Birth Weight|Infant, Premature|Ductus Arteriosus, Patent
Interventions: DRUG: indomethacin|DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Safety and Efficacy of Piperacillin/Tazobactam and Ampicillin/Sulbactam in Patients With Diabetic Foot Infections
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Foot
Interventions: DRUG: Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transdermal Fentanyl for Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Peripheral Neuropathy|Complex Regional Pain Syndromes (CRPS)
Interventions: DRUG: Transdermal Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Diagnostic Contribution of High-throughput Exome Sequencing for Patients With Convulsive Encephalopathy of Unknown Etiology: Pilot Study to Improve Genetic Counselling
Status: COMPLETED
Conditions: Epileptic Encephalopathy of Unindentified Genetic Origin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Psychotherapeutic Intervention Model in Nursing
Status: NOT_YET_RECRUITING
Conditions: Anxiety Generalized
Interventions: BEHAVIORAL: NIC Psychotherapeutic Intervention(s) for İneffective Coping|BEHAVIORAL: psychotherapeutic intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Compared to Adapalene 0.1% Gel Plus Doxycycline in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne
Interventions: PROCEDURE: Photodynamic therapy|DRUG: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A Prospective Randomized Trial
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: RADIATION: External beam radiation|DRUG: Lupron|DRUG: Casodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation for Batch Consistency of Ad5-nCoV in Chinese Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: batch 1 of Ad5-nCoV|BIOLOGICAL: batch 2 of Ad5-nCoV|BIOLOGICAL: batch 3 of Ad5-nCoV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Paratracheal and Cricoid Pressure on the Placement of the I-gel.
Status: COMPLETED
Conditions: Paratracheal Pressure
Interventions: OTHER: Placement of the i-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Prospective, Randomized, Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO) or Standard Care Dressings (AQUACEL Ag SURGICAL Dressing).
Status: UNKNOWN
Conditions: Surgical Incision
Interventions: DEVICE: PICO|DEVICE: Aquacel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erlotinib and Carboplatin in Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Time-efficient Strategies to Improve Fitness for Surgery in Older Adults
Status: UNKNOWN
Conditions: Perioperative Hypertension|Hypertension
Interventions: OTHER: HIIT|OTHER: HOLD|OTHER: HUG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Lymphedema With Bio-Electrical Impedance Analysis in Patients After Breast Cancer Surgery
Status: WITHDRAWN
Conditions: Lymphedema|Breast Cancer
Interventions: DEVICE: Bio Impedance Analysis Measurement|DEVICE: Tissue Dielectric Constant Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Personalized Integrated Chronotherapy for Perinatal Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Postpartum Depression|Prenatal Disorder|Circadian Dysregulation|Pregnancy Related|Sleep Disturbance
Interventions: BEHAVIORAL: Personalized Integrated Chronotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity and Safety of an Investigational Pandemic Influenza Vaccine in Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Biologicals' investigational vaccine GSK1562902A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Silver-impregnated Suprapubic Catheters (SPC) in Urogynecology
Status: COMPLETED
Conditions: Infection Associated With Catheter|Urinary Tract Infection
Interventions: DEVICE: silver SPC|DEVICE: standard SPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.
Status: UNKNOWN
Conditions: Pain, Postoperative|Pruritus|Nausea, Postoperative|Vomiting, Postoperative
Interventions: DRUG: Morphine Sulfate|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Axitinib in Metastatic Non-clear Cell Renal Cell Carcinoma Patients Previously Treated With Temsirolimus
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Nonclear Cell|Temsirolimus Resistance
Interventions: DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Therapies in Children With Hemiplegia
Status: COMPLETED
Conditions: Infantile Hemiplegia
Interventions: COMBINATION_PRODUCT: intensive therapies(CIMT/BIT): protocol 1 or protocol 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthesia Using Ultrasound Assistance Versus Conventional Palpation in Morbidly Obese Patients
Status: RECRUITING
Conditions: Spinal Anesthesia|Ultrasound Assistance|Obesity, Morbid
Interventions: PROCEDURE: Paramedian conventional palpation group|PROCEDURE: Ultrasound assistance paramedian spinal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers
Status: RECRUITING
Conditions: HPV 16+ Recurrent or Metastatic Cancer
Interventions: BIOLOGICAL: CD8 reduced peripheral blood cells taken from related donors vaccinated against HPV16|BIOLOGICAL: Non-myeloablative allogeneic bone marrow transplant from related donors vaccinated against HPV16
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors
Status: COMPLETED
Conditions: Brain Tumor, Recurrent
Interventions: DRUG: Photofrin (porfimer sodium) & photodynamic therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants
Status: TERMINATED
Conditions: Extreme Prematurity - Less Than 28 Weeks
Interventions: OTHER: Neonatal Resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain
Status: RECRUITING
Conditions: Bunion
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zero Positive End-expiratory Pressure Before Emergence Prevents Postoperative Atelectasis.
Status: COMPLETED
Conditions: Atelectasis|Oxygenation
Interventions: PROCEDURE: ZEEP|PROCEDURE: PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Bosutinib-Exemestane Combination Vs Exemestane Alone in Post Menopausal Women With Breast Cancer
Status: TERMINATED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Bosutinib|DRUG: exemestane|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
Status: COMPLETED
Conditions: Endometritis|Wound Infection|Abscess|Surgical Site Infection
Interventions: DRUG: Azithromycin and standard of care|DRUG: Placebo and standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Care Strategies to Reduce High Blood Pressure: A Cluster Randomized Trial in Rural Bangladesh, Pakistan and Sri Lanka
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: multi-component interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Evaluation of Premalignant Lesions in the Biliary Tract and Pancreatic Ducts
Status: COMPLETED
Conditions: Benign Neoplasm of Liver and/or Biliary Ducts|Neoplasm of Uncertain Behavior of Biliary System|Benign Neoplasms of the Pancreas|Neoplasms of the Pancreas
Interventions: PROCEDURE: Duodenoscopy, pancreatoscopy, cholangioscopy, confocal microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Intraventricular Electrical Activation in Resynchronization Therapy
Status: COMPLETED
Conditions: Heart Failure|Cardiomyopathy, Dilated|Coronary Disease
Interventions: DEVICE: Invasive mapping with CARTO3 system and Non-Invasive mapping with CardioInsight Atlas EC Mapping system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAMucirumab in Combination Wth TAS102 vs. TAS102 Alone in Chemotherapy Refractory Metastatic Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Ramucirumab|DRUG: TAS 102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Disposition of Radio-labeled AVE8062 Compound Administered as a 30-minute IV Infusion to Patients With Advanced Solid Tumor
Status: COMPLETED
Conditions: Neoplasms, Malignant
Interventions: DRUG: Ombrabulin (AVE8062)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Ovarian, Primary Peritoneal or Fallopian Tube Cancer Study for Patients That Have Not Received Prior Chemotherapy
Status: COMPLETED
Conditions: Genital Neoplasms, Female|Fallopian Tube Neoplasms|Ovarian Neoplasms|Pelvic Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My Best GI Eating Study
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Eating Plan 1|BEHAVIORAL: Eating Plan 2|BEHAVIORAL: Eating Plan 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Periodontal Treatment on Systemic Inflammatory Mediators
Status: COMPLETED
Conditions: Periodontal Disease|Coronary Heart Disease
Interventions: PROCEDURE: Delayed treatment|PROCEDURE: Periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy
Status: TERMINATED
Conditions: Familial Hypercholesterolemia
Interventions: DRUG: Implitapide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study To Assess Guidance in and Subsequent Use of Mind-Body Techniques on the Quality of Life of Cancer Patients
Status: TERMINATED
Conditions: Quality of Life|Life Change Events|Neoplasms
Interventions: BEHAVIORAL: Face-to-Face MBM Skills Group|OTHER: Waitlist Control I|OTHER: Waitlist Control II|BEHAVIORAL: Online MBM Skills Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Finding, Safety and Efficacy of Monthly Subcutaneous Canakinumab Administration in Metformin Monotherapy Treated Type 2 Diabetic Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canakinumab|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blueberry Effects on Dark Vision and Glare Recovery
Status: COMPLETED
Conditions: Blindness and Low Vision
Interventions: DIETARY_SUPPLEMENT: Blueberry Juice S2|DIETARY_SUPPLEMENT: Blueberry Capsules S2|DIETARY_SUPPLEMENT: Placebo Capsule S2|DIETARY_SUPPLEMENT: Placebo Juice L1|DIETARY_SUPPLEMENT: Blueberry Juice L1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial Study of Knee System in Primary Total Knee Arthroplasty in China
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Osteoarthritis|Post-traumatic; Arthrosis
Interventions: DEVICE: Total Knee System made in China (Sigama, CoCr, PFC)|DEVICE: Total Knee System made outside of China (Sigama, NP, PFC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: FST-201 In The Treatment of Acute Fungal Otitis Externa
Status: TERMINATED
Conditions: Acute Fungal Otitis Externa
Interventions: DRUG: FST-201 (dexamethasone 0.1%) Otic Suspension|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Radiotherapy in Treating Primary Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Primary Hepatocellular Carcinoma
Interventions: RADIATION: SBRT|RADIATION: IMRT|PROCEDURE: Hepatectomy|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate a Subcutaneous Four Months Sustained-release Formulation of Triptorelin in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Triptorelin (Decapeptyl®) - Treatment 8 months (pivotal study) followed by a treatment extension of 8 months (extension study)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Randomized, Single-blind, Controlled, Single Center Study to Evaluate the Safety and Immunogenicity of a Dose Range of Glycoconjugate Antigen Vaccine of Group B Streptococcus in Healthy Women 18- 40 Years of Age
Status: COMPLETED
Conditions: Invasive Group B Streptococcus (GBS) Disease
Interventions: BIOLOGICAL: GBS glycoconjugate vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder|Bipolar Depression
Interventions: DRUG: Xenon|DRUG: Nitrogen gas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Efficacy and Safety in Volunteers of DCF100, TIB200 and SPR300 vs. Placebo and Control(s) in a UV Pain Model
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen|DRUG: Diclofenac|DRUG: Methyl-salicylate / Menthol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Hydromorphone (Standardized, weight-based dosing)|DRUG: Morphine Sulfate (Standardized, weight-based dosing)|DRUG: Hydromorphone (Patient Specific dosing)|DRUG: Morphine Sulfate (Patient Specific dosing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Third Molar Extraction and Pulsed Electromagnetic FieldTherapy
Status: TERMINATED
Conditions: Postoperative Edema and Pain
Interventions: DEVICE: ActiPatch(TM)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Self-administered Acupressure for Symptom Management of Caregiver Stress
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Self-administered acupressure|OTHER: wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: Burns
Interventions: BIOLOGICAL: EHSG-KF|BIOLOGICAL: STSG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NHS-IL12 for Solid Tumors
Status: COMPLETED
Conditions: Epithelial Neoplasms, Malignant|Epithelial Tumors, Malignant|Malignant Mesenchymal Tumor
Interventions: DRUG: NHS-IL-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Topical Application of Tranexamic Acid in Total Hip Arthroplasty Through the Direct Anterior Approach
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Postoperative Blood Loss
Interventions: DRUG: Tranexamic Acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Superhydrophilic Surface of Lance CLEAR Implants on the Marginal Bone Loss and Survival in Diabetic and Non Diabetic Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetes
Interventions: DEVICE: Lance CLEAR dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shade Matching and Patient Satisfaction of Yttria Stabilized Multilayered Zirconia and Lithium Disilicate Restorations
Status: NOT_YET_RECRUITING
Conditions: Mutilated Teeth|Endodontically Treated Teeth
Interventions: OTHER: Yttria stabilized multilayered (YML) zirconia restorations|OTHER: Lithium disilicate restorations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Biomarkers of the Alzheimer's Disease (AD) in Elderly Patients With New-onset Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: BIOLOGICAL: profile of CSF biomarkers of AD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Safety and Efficacy of HG102 as Compared to Botox® in Subject With Moderate to Severe Glabellar Lines
Status: RECRUITING
Conditions: Glabellar Lines
Interventions: DRUG: Botulinum Toxin Type A Injection [HG102]|DRUG: Botulinum Toxin Type A Injection [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Non-interfering Arterial Blood Pressure Monitoring Device
Status: WITHDRAWN
Conditions: Hypertension|Hypotension|Healthy
Interventions: DEVICE: 3M|DEVICE: ContiPressTM|DEVICE: Mobil-O-Graph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: S0354, Anti-IL-6 Chimeric Monoclonal Antibody in Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: CNTO 328
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin for the Treatment of Non-alcoholic Steatohepatitis in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes|Nonalcoholic Steatohepatitis
Interventions: DRUG: sitagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Non-replicating ChAdOx1 Vector Vaccine AZD1222 (COVISHIELD), for Prevention of COVID-19 in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: Covishield
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Production of Fortified Biscuit With Chickpea and Crushed Peanut for Improving Cognitive Performance
Status: COMPLETED
Conditions: Cognitive Performance
Interventions: DIETARY_SUPPLEMENT: Chickpeas and crushed peanuts fortified biscuit|OTHER: Cognitive stimulation for the mothers|OTHER: Cognitive stimulation for students
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Montelukast as a Controller of Atopic Syndrome
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Allergic Conjunctivitis|Atopic Eczema|Asthma
Interventions: DRUG: montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)
Status: COMPLETED
Conditions: Urinary Incontinence|Fecal Incontinence|Urge Incontinence|Nocturia|Urinary Frequency More Than Once at Night|Bowel Disorders Functional|Urinary Incontinence, Urge|Incontinence, Nighttime Urinary
Interventions: DEVICE: UCon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Para-aortic Prophylactic Irradiation for Locally Advanced Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: RADIATION: Paraaortic prophylactic irradiation and pelvic definitive concurrent chemoradiation|RADIATION: Pelvic definitive concurrent chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells
Status: SUSPENDED
Conditions: Thalassemia Major
Interventions: BIOLOGICAL: γ-globin reactivated autologous hematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Evaluate the Safety and Preliminary Efficacy of the Peritec Peritoneal Lined Stent and Delivery System
Status: UNKNOWN
Conditions: Vascular Disease, Peripheral
Interventions: PROCEDURE: Endovascular Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy
Status: COMPLETED
Conditions: Debilitating Fibrosing Skin Disorders (Localised Scleroderma, Eosinophilic Fasciitis)
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell-free DNA Methylation for Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|DNA Methylation|Benign Ovarian Tumor|Training Set|Validation Set|Cell-free DNA|Liquid Biopsy
Interventions: DIAGNOSTIC_TEST: DNA methylation testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bariatric Surgery for the Treatment of Type 2 Diabetes - Clinical Effects and Underlying Mechanisms
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: PROCEDURE: Laparoscopic Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Migraine Prevention Using ActiPatch
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Pulsed Shortwave Therapy|DEVICE: Placebo Pulsed Shortwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda
Status: UNKNOWN
Conditions: Porphyria Cutanea Tarda
Interventions: DRUG: Exjade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ETT Rotation During Nasal Fiberoptic Intubation
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Pre-Rotated (Group R)|OTHER: No pre-rotation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Peri-articular Tranexamic Acid Injection in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Peri-articular tranexamic acid|DRUG: Intravenous tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones
Status: COMPLETED
Conditions: Renal Stone
Interventions: DRUG: Lidocaine gel,|DRUG: Naproxen Sodium|DRUG: Lidocaine gel and Naproxen Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain.
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: 75 mg linzagolix tablet|DRUG: 200 mg linzagolix tablet|DRUG: Add-back capsule (E2 1 mg / NETA 0.5 mg)|DRUG: Placebo tablet to match 75 mg linzagolix tablet|DRUG: Placebo tablet to match 200 mg linzagolix tablet|DRUG: Placebo capsule to match Add-back capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Iloprost on Pulmonary Oxygenation in Obese Patients During One-lung Ventilation
Status: UNKNOWN
Conditions: Lung Cancer (Including Metastatic Cancer)|Pulmonary Infection
Interventions: DRUG: normal saline inhalation|DRUG: iloprost inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Managing AsThma AnD Obesity Related Symptoms (MATADORS) Feasibility Study
Status: COMPLETED
Conditions: Asthma in Children|Obesity|Obesity, Adolescent|Obesity, Childhood
Interventions: BEHAVIORAL: MATADORS|BEHAVIORAL: MATADORS Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Yoga and Laughter Yoga on Increasing the Psychological Resilience of Mothers
Status: COMPLETED
Conditions: Depression|Stress|Anxiety|Psychological Resilience
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Laughter Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Efficacy of Neoadjuvant Cabozantinib Plus Nivolumab (CaboNivo) Followed by Definitive Resection for Patients With Locally Advanced Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Locally Advanced Hepatocellular Carcinoma
Interventions: DRUG: Cabozantinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Otoprotection With SPI-1005 for Prevention of Temporary Auditory Threshold Shift
Status: COMPLETED
Conditions: Temporary Auditory Threshold Shift
Interventions: DRUG: SPI-1005 Low dose|DRUG: SPI-1005 Middle dose|DRUG: SPI-1005 High dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: t-RNS After Hand Recovery in Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: transcranial random noise stimulation and functional electrical stimulation facilitated task practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Infertility, Female
Interventions: DEVICE: May Health System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy
Status: COMPLETED
Conditions: Chronic Periodontitis|Type 2 Diabetes Mellitus
Interventions: PROCEDURE: non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug-Drug Interaction Study of VX-770 and VX-809 in Healthy Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-809|DRUG: VX-770|DRUG: VX-809 placebo|DRUG: VX-770 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ArthroPlanner: A Surgical Planning Solution for Acromioplasty
Status: UNKNOWN
Conditions: Shoulder Impingement Syndrome|Subacromial Impingement Syndrome|Tendon Injuries
Interventions: PROCEDURE: Acromioplasty with planning|PROCEDURE: Acromioplasty without planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Navigation 2.0
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Patient Navigation (PN) 2.0 Checklist|BEHAVIORAL: One-on-one Patient Navigation (PN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sacrocolpopexy Versus Sacro-spinous Fixation for Prolapse Treatment
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Sacro-spinous fixation|PROCEDURE: Subtotal hysterectomy|PROCEDURE: Sacrocolpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reposition of Second Line Treatment in Chronic Immune Thrombocytopenia
Status: COMPLETED
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Hydroxychloroquine|DRUG: vincristine|DRUG: azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-free Anesthesia, Optimization of Anesthesia After Bariatric Surgery
Status: RECRUITING
Conditions: Analgesics, Opioid|Anesthesia; Adverse Effect
Interventions: PROCEDURE: Intubation|DRUG: TIVA versus Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer Cycles
Status: COMPLETED
Conditions: Endometrial Preparation|Frozen Embryo Transfer
Interventions: DRUG: Sildenafil|DRUG: estradiol valerat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Hygiene and Peri-Implant Tissues Homeostasis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: OTHER: Tooth-borne treatment|OTHER: Implant-specific treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of 3 Vaccinations With TICOVAC in 2 Dosages in Healthy Children Aged Between 6 Months and 3 Years
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Tick-Borne Encephalitis (TBE) Vaccine (Inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Post Operative Sore Throat
Interventions: DRUG: Ketamine|OTHER: saline nebulization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REOXCARE Dressing to Improve Healing in Diabetic Foot Ulcers (DFU)
Status: COMPLETED
Conditions: Diabetes Mellitus|Foot Ulcer|Neuroischemic Foot Ulcer
Interventions: DEVICE: Reoxcare antioxidant dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage
Status: NOT_YET_RECRUITING
Conditions: Skin Care
Interventions: DEVICE: Liquid bandage|DEVICE: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING