pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prefontal tDCS in Patients With Disorders of Consciousness: Neurophysiological and Behavioural Outcomes
Status: COMPLETED
Conditions: Vegetative State|Minimally Conscious State|Disorder of Consciousness
Interventions: DEVICE: anodal tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: BiDil XR|DRUG: BiDil Immediate Release (IR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Photogrammetry for Manual Skills Training in Undergrad Physiotherapy Students
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: BEHAVIORAL: Simulating video|BEHAVIORAL: Conventional video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Screening for Familial Gastric Cancer in First Degree Relatives
Status: TERMINATED
Conditions: Malignant Neoplasm of Stomach|Carcinoma, Diffuse Type|Intestinal Type Adenocarcinoma of Stomach|Relative (Related Person)
Interventions: OTHER: Endoscopy with staining of the mucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer and in Women at Risk of Developing Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry|OTHER: medical chart review|PROCEDURE: evaluation of cancer risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: methotrexate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assesment of the Efficacy of Personalized Parent-child Psychotherapy in Children Under 3 Years Old
Status: RECRUITING
Conditions: Child Behavior Disorders|Parent-Child Relations
Interventions: BEHAVIORAL: Personalized psychotherapy|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sweeping the Membranes, Cervical Length and Duration of Labor
Status: COMPLETED
Conditions: Disorder of Amniotic Cavity and/or Membrane
Interventions: PROCEDURE: sweeping the membranes|OTHER: No sweeping group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heads up Messages to Increase Call Pick-up Rates
Status: NOT_YET_RECRUITING
Conditions: Various: Health Insurance Members That Could Benefit From Being Connected to a Specialist, e.g., Orthopedic Doctor to Treat Back Pain
Interventions: OTHER: Message variation 1|OTHER: Message variation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurogenic Bladder|Spinal Cord Injuries
Interventions: DRUG: Gentamicin Sulfate|OTHER: Placebo instillation (saline alone)|OTHER: No instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Naloxegol|OTHER: Placebo|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fractional CO2 Laser for the Treatment of Lichen Planus Pigmentosus
Status: WITHDRAWN
Conditions: Lichen Planus Pigmentosus
Interventions: DEVICE: CO2 fractional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Ivonescimab for First-line Treatment of Metastatic Squamous NSCLC Patients
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ivonescimab Injection|BIOLOGICAL: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Sotagliflozin (LX4211) in Patients With Inadequately Controlled Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin|DRUG: Placebo|DRUG: Sotagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Biologics + Methotrexate With Biologics + Tacrolimus in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: tacrolimus|DRUG: methotrexate|BIOLOGICAL: adalimumab|BIOLOGICAL: tocilizumab|BIOLOGICAL: abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab and Fresh Frozen Plasma in Patients With Chronic Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Ofatumumab + Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vonoprazan Study in Patients With Erosive Esophagitis to Evaluate Long-term Safety
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Vonoprazan|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogeneicity of Multivalent Pneumococcal Conjugate Vaccine in Healthy Adults
Status: UNKNOWN
Conditions: Pneumococcal Infection
Interventions: BIOLOGICAL: LBVE01|BIOLOGICAL: LBVE02|BIOLOGICAL: Prevnar13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of Oral Glutamine in Patients With Sickle Cell Anemia
Status: TERMINATED
Conditions: Anemia, Sickle Cell
Interventions: DRUG: Glutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Surgery for Gastrointestinal Disorders: A Multicenter Registry Study
Status: ENROLLING_BY_INVITATION
Conditions: Achalasia|Gastric Outlet Obstruction|Gastroparesis|GERD|Reflux|Fistula|Benign Neoplasm
Interventions: PROCEDURE: Endoscopic Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Muraglitazar Versus Pioglitazone in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Muraglitazar|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of Recombinant Chimeric Anti-CD20 Monoclonal Antibody in Patients With B-cell Non-Hodgkin's Lymphoma.
Status: COMPLETED
Conditions: B-cell Non Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Chimeric anti-CD20 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Novel Noise Reduction Principles in Hearing Instruments
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Measures of Standard Noise Reduction NR1|DEVICE: Measures of Noise Reduction Principle NR2|DEVICE: Measure of Noise Reduction Principle NR3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Locally Advanced NSCLC Hyperfractionated RT
Status: COMPLETED
Conditions: Carcinoma, Non Small Cell Lung (NSCLC)
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Daily hyperfractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind The Gap - Crossing Borders Study
Status: COMPLETED
Conditions: Emphysema|COPD|Hyperinflation Lung
Interventions: DEVICE: Bronchoscopic transparenchymal interlobar fissure closure using Aeriseal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic and Predictive Factors for Small Breast Tumors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Endocrine therapy|RADIATION: Radiotherapy|DRUG: Herceptin|DRUG: Chemotherapy|PROCEDURE: Type of breast cancer surgery|OTHER: Age at diagnosis|OTHER: Screen detected tumor|OTHER: Menopausal status at diagnosis|OTHER: Tumor size|OTHER: Estrogen receptor (ER) status|OTHER: Tumor grade|OTHER: HER2-status|OTHER: Intrinsic subgroups of breast cancer|OTHER: Nodal status
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate the Effect of an Extract of Sclerocaya Birrea on Prediabetic Subjects
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: nutraceutical|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy
Status: UNKNOWN
Conditions: Herniated Disc
Interventions: PROCEDURE: conservative discectomy|PROCEDURE: aggressive discectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Xeloda (Capecitabine) in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 5 FU|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Oxaliplatin|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Treatment of Atopic Dermatitis With Concurrent Altabax® and Topical Low-Potency Corticosteroids Versus Low-Potency Corticosteroid Mono-therapy
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Altabax (R)|DRUG: Vehicle and Locoid lipocream (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LISA vs INSURE in Extremely Low Birth Weight Infants. A Manikin Study
Status: COMPLETED
Conditions: Respiratory Distress Syndrome|Preterm Birth|Surfactant Deficiency Syndrome Neonatal
Interventions: PROCEDURE: LISA approach|PROCEDURE: Insure approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPO2-PV: Evaluation of Pre-Oxygenation Conditions in Morbidly Obese Volunteer: Effect of Position and Ventilation Mode
Status: COMPLETED
Conditions: Morbid Obesity|Bariatric Surgery Candidate
Interventions: PROCEDURE: NIPPV|PROCEDURE: Tidal volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis
Status: COMPLETED
Conditions: Severe Alcoholic Hepatitis
Interventions: DRUG: G-CSF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Light-Scattering Spectroscopy for Detection of Breast Cancer
Status: TERMINATED
Conditions: Healthy, no Evidence of Disease|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: PROCEDURE: light-scattering spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Recombinant Zoster Vaccine in Stable SLE Patients
Status: RECRUITING
Conditions: Herpes Zoster|Recombinant Zoster Vaccine|Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Recombinant zoster vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Small Cell Neuroendocrine Carcinoma|Bladder Squamous Cell Carcinoma|Bladder Urothelial Carcinoma|Clear Cell Renal Cell Carcinoma|Invasive Bladder Plasmacytoid Urothelial Carcinoma|Invasive Bladder Sarcomatoid Urothelial Carcinoma|Invasive Sarcomatoid Urothelial Carcinoma|Kidney Medullary Carcinoma|Malignant Genitourinary System Neoplasm|Malignant Solid Neoplasm|Penile Carcinoma|Penile Squamous Cell Carcinoma|Renal Cell Carcinoma|Renal Pelvis Urothelial Carcinoma|Sarcomatoid Renal Cell Carcinoma|Stage III Bladder Cancer AJCC v8|Stage III Penile Cancer AJCC v8|Stage III Renal Cell Cancer AJCC v8|Stage III Renal Pelvis and Ureter Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Penile Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8|Stage IV Renal Pelvis and Ureter Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Ureter Urothelial Carcinoma|Urethral Urothelial Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil as Adjunct Treatment for Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: fish oil capsule|DIETARY_SUPPLEMENT: soybean oil capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Anti-malarial Treatment Options in Guinea-Bissau - Part A
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-lumefantrine|DRUG: Dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Aware AET Non-Initiation Intervention
Status: RECRUITING
Conditions: Breast Cancer|Survivorship|Treatment Compliance|Treatment Adherence|Treatment Refusal
Interventions: BEHAVIORAL: Culturally Aware Adjuvant Endocrine Therapy (AET) Non-Initiation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Educational Program on Parental Stress of Parents of Children With CHD
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Defect
Interventions: OTHER: psychoeducational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Functional Remediation in Patients With Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Functional Remediation|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate for Preterm Birth (MASP Study)
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes and Moderate Renal Impairment
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis
Status: RECRUITING
Conditions: Intracanal Medication
Interventions: DRUG: Calcium Hydroxide Intracanal medication|DRUG: Leddermix Intracanal medication|DRUG: Asiaticoside Intracanal medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aflibercept Injection Into the Vitreous Body of the Eye: Study to Learn More About Patient Relevant Outcomes, Real World Treatment Patterns and How Well the Treatment Works for Patients Suffering From Abnormal Growth of New Blood Vessels Under the Retina.
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Ivt. Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dietary Supplement With and Without a Probiotic
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DIETARY_SUPPLEMENT: Complex oligosaccharide|DIETARY_SUPPLEMENT: Probiotic|OTHER: PPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo to BI 113608 high dose b.i.d.|DRUG: Placebo to BI 113608 low dose b.i.d.|DRUG: BI 113608 high dose b.i.d.|DRUG: Placebo to BI 113608 medium dose b.i.d.|DRUG: BI 113608 low dose b.i.d.|DRUG: BI 113608 medium dose b.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CD19 CAR-T Cells for Patients With Relapse and Refractory CD19+ B-ALL.
Status: UNKNOWN
Conditions: B-cell Acute Lymphocytic Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: CD19 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot: Feasibility of Intermittent Enteral Feeding in Ventilated MICU Patients
Status: COMPLETED
Conditions: Nutrition
Interventions: DIETARY_SUPPLEMENT: Intermittent Enteral Nutrition Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation The Artificial Intelligence System for Automatic Evaluation of the Extent of Intestinal Metaplasia
Status: UNKNOWN
Conditions: Intestinal Metaplasia of Gastric Mucosa|Artificial Intelligence|Endoscopy
Interventions: DIAGNOSTIC_TEST: The diagnosis of Artificial Intelligence and endosopists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Facilitating Aftercare for Alcohol Detox Patients
Status: COMPLETED
Conditions: Alcohol Abuse|Alcohol Dependence
Interventions: BEHAVIORAL: Motivation Enhancement Therapy (MET)|BEHAVIORAL: Peer-Twelve Step Facilitation (P-TSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Nerve Group Block for Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthropathy|Postoperative Pain
Interventions: PROCEDURE: Pericapsular nerve group block with saline solution|PROCEDURE: Pericapsular nerve group block with ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery
Status: RECRUITING
Conditions: Opioid Use|Postoperative Pain
Interventions: OTHER: 5x Oxycodone Oral Tablets|OTHER: 16x Oxycodone Oral Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Drug Interaction Between Dolutegravir (DTG) and Daclatasvir (DCV) in Healthy Adult Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: DTG|DRUG: DCV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALPP CAR-T Cells for ALPP-Positive Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: ALPP CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke
Status: COMPLETED
Conditions: Stroke|Shoulder Injury
Interventions: PROCEDURE: Taping and Sham Taping|PROCEDURE: Sham Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Liraglutide in Combination With an OAD in Subjects With Type 2 Diabetes Insufficiently Controlled on OAD Alone
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: oral anti-diabetic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety of RP-L102 in Pediatric Subjects With Fanconi Anemia Subtype A
Status: UNKNOWN
Conditions: Fanconi Anemia Complementation Group A
Interventions: BIOLOGICAL: RP-L102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomics in Michigan to AdJust Outcomes in Prostate canceR (G-MAJOR) for Men With Newly Diagnosed Favorable Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Decipher|DEVICE: Prolaris|DEVICE: Oncotype Dx Genomic Prostate Score (GPS)|OTHER: Standard of care (askMUSIC score)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer
Status: SUSPENDED
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Lutetium Lu 177 dotatate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital
Status: COMPLETED
Conditions: Cholangitis|Liver Cirrhosis, Biliary|Cholestasis|Liver Diseases|Liver Cirrhosis|Bile Duct Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a Parent/Child Cognitive-Behaviorial Therapy Program in ADHD Children With Emotional Dysregulation Profile
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity|Attention-Deficit-Disordered Children
Interventions: BEHAVIORAL: Cognitive Behavorial Therapy (CBT)|BEHAVIORAL: Body mediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Status: COMPLETED
Conditions: Postoperative Infection|Postoperative Complications
Interventions: PROCEDURE: Soak and Scrub|PROCEDURE: Clorhexadine scrub
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation of AcrySof® IQ PanOptix™ IOL Model TFNT00
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AcrySof IQ PanOptix Multifocal IOL|DEVICE: AcrySof Monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Telehealth for Wheelchair Users
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Paraplegia|Pressure Ulcer, Buttock
Interventions: DEVICE: An interactive telehealth monitoring and biofeedback system|BEHAVIORAL: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: BLI801 Laxative|DRUG: BLI801 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Sarcoma|Dedifferentiated Chondrosarcoma|Giant Cell Tumor of Bone|Malignancy in Giant Cell Tumor of Bone|Malignant Solid Neoplasm|Ovarian Carcinosarcoma|Platinum-Resistant Ovarian Carcinoma|Poorly Differentiated Thyroid Gland Carcinoma|Recurrent Osteosarcoma|Recurrent Ovarian Carcinoma|Refractory Osteosarcoma|Soft Tissue Sarcoma|Thyroid Gland Anaplastic Carcinoma|Thyroid Gland Squamous Cell Carcinoma|Undifferentiated High Grade Pleomorphic Sarcoma of Bone|Triple Negative Breast Cancer
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: Autologous Tumor Infiltrating Lymphocytes LN-145|BIOLOGICAL: Autologous Tumor Infiltrating Lymphocytes LN-145-S1|DRUG: Cyclophosphamide|DRUG: Fludarabine|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine (Synflorix™) When Administered to Children Who Are at an Increased Risk of Pneumococcal Infection
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae Vaccines
Interventions: BIOLOGICAL: Synflorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Status: RECRUITING
Conditions: Severe Aplastic Anemia|MDS (Myelodysplastic Syndrome)
Interventions: DEVICE: Miltenyi CD34 Reagent System|OTHER: Donor derived G-CSF mobilized PBC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-frequency Oscillatory Ventilation (HFOV) in Preterm Infants With Severe Respiratory Distress Syndrome (RDS)
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DEVICE: mechanical ventilation (SLE 5000, Servo-i-Maquet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of the Cochlear Nucleus CI422 Cochlear Implant in Adults
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Nucleus CI422 Cochlear Implant with N6 Sound Processor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abequolixron (RGX-104) and Durvalumab in Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Carboplatin|DRUG: Abequolixron|DRUG: Abraxane|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLIF Correction VS. Conventional Correction Strategy for ASD
Status: NOT_YET_RECRUITING
Conditions: Spinal Deformity
Interventions: PROCEDURE: CLIF correction|PROCEDURE: conventional correction strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Vaccine Responses in Subcutaneous Amlitelimab Treated Atopic Dermatitis Participants Aged 18 Years and Older Compared With Placebo
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab|DRUG: Placebo|BIOLOGICAL: Tdap vaccine|BIOLOGICAL: PPS vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The FAVOR II China Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Cardiovascular Diseases|Arteriosclerosis|Coronary Disease|Arterial Occlusive Diseases|Heart Diseases|Vascular Diseases
Interventions: DIAGNOSTIC_TEST: Fractional Flow Reserve (FFR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Symptoms and Quality of Life in Chronic Heart Failure: Pilot Study
Status: COMPLETED
Conditions: Chronic Heart Failure (CHF)
Interventions: OTHER: Collaborative Care to Alleviate Symptoms and Adjust to Illness|BEHAVIORAL: Psychospiritual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Venous-Return Assist Device (Venowave) to Treat Post-Thrombotic Syndrome: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Postphlebitic Syndrome
Interventions: DEVICE: Veno-device (Venowave)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Army-SPRING Army-Suicide Prevention Research
Status: NOT_YET_RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Army-SPRING|BEHAVIORAL: Risk Reduction Group (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Insomnia|Generalized Anxiety Disorder
Interventions: DRUG: Eszopiclone (Lunesta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Brigatinib in Japanese Participants With Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: ALK-positive Advanced NSCLC
Interventions: DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dissecting of The Inferior Pulmonary Ligament on Postoperative Pulmonary Reexpansion and Recurrence
Status: UNKNOWN
Conditions: Pneumothorax
Interventions: PROCEDURE: DIPL|PROCEDURE: WR|PROCEDURE: thoracoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: AN2728 ointment, 2%|DRUG: AN2898 ointment, 1%|DRUG: AN2898 ointment vehicle|DRUG: AN2728 ointment vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Repeated Doses of DX-88 (Ecallantide) to Treat Attacks of Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: ecallantide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of High-dose Dual Therapy and Half-dose Clarithromycin-containing Bismuth Quadruple Therapy for H.P Eradication in Elderly Patients
Status: UNKNOWN
Conditions: Helicobacter Pylori
Interventions: DRUG: Lansoprazole, Amoxicillin|DRUG: Lansoprazole, Amoxicillin,Clarithromycin and Bismuth subcitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PDT vs Peels for Treatment of Actinic Keratoses
Status: NOT_YET_RECRUITING
Conditions: Actinic Keratoses
Interventions: PROCEDURE: Photodynamic Therapy|DRUG: Chemical Peels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Exercise Post-treatment Intervention in Lean Mass Recovery in Breast Cancer Survival.
Status: UNKNOWN
Conditions: Sarcopenic Obesity in Breast Cancer Survival|Muscle Strength Quantitative Trait Locus 1|Cardiopulmonary Capacity|Quality of Life|Fatigue|Depression
Interventions: OTHER: Physical Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: PENG Block with 0.25% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout
Status: RECRUITING
Conditions: Acute Gout
Interventions: DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 100 mg (phase Ib)|DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg (phase Ib)|DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 300 mg (phase Ib)|DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg (phase II)|DRUG: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection low dose 300 mg (phase II)|DRUG: Compound Betamethasone Injection (phase II)|OTHER: Placebo (phase II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Vertebral Osteoporosis Incidentally Detected to Prevent Future Fractures
Status: COMPLETED
Conditions: Osteoporosis
Interventions: BEHAVIORAL: Reminders and opinion leader generated guidelines +/- leaflets and counselling|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reduced Infant Response To A Routine Care Procedure After Glucose 25% Analgesia
Status: TERMINATED
Conditions: Infant|Newborn Diseases
Interventions: DRUG: Glucose 25%|DRUG: Glucose 25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Glioma|Gliosarcoma|Malignant Brain Tumor|Ependymoma|Medulloblastoma|Diffuse Intrinsic Pontine Glioma|Primary CNS Tumor
Interventions: DRUG: Indoximod|DRUG: Temozolomide|RADIATION: Conformal Radiation|DRUG: Cyclophosphamide|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Evaluation of Safety of Escalating Dose Levels of MEDI-507 in Patients for Treatment of at Least Grade II Graft-Versus-Host Disease (GvHD)
Status: COMPLETED
Conditions: Graft-Versus-Host Disease
Interventions: DRUG: MEDI-507|DRUG: MEDI-507|DRUG: MEDI-507|DRUG: MEDI-507|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Profiling in Lung Cancer Patients
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Carcinoma
Interventions: DRUG: pemetrexed|DRUG: cisplatin|PROCEDURE: Radical Non-Small Cell Lung Cancer (NSCLC) surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery
Status: TERMINATED
Conditions: Kidney Cancer|Prostate Cancer
Interventions: DRUG: Lidocaine Hydrochloride 0.8% in Dextrose 5% Solution|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of an Antiviral Drug (Valaciclovir) in the Treatment of Generalized Periodontitis (Stage III or IV and Grade A, B or C): Prospective, Randomized and Double Blind Clinical Trial
Status: RECRUITING
Conditions: Periodontitis Chronic Generalized Severe
Interventions: DRUG: Antiviral treatment with conventional non-surgical treatment|DRUG: Placebo with conventional non-surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare SB17 (Proposed Ustekinumab Biosimilar) to Stelara® in Subject With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Moderate to Severe Plaque Psoriasis
Interventions: DRUG: Stelara® (Ustekinumab)|DRUG: SB17 (Proposed Ustekinumab Biosimilar)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of EGF With Silver Sulfadiazine Cream Compared With Silver Zinc Sulfadiazine Cream for Treatment of Burn Wound
Status: COMPLETED
Conditions: Deep Partial Thickness Burn
Interventions: DRUG: Epidermal growth factor with silver sulfadiazine cream|DRUG: Silver zinc sulfadiazine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Single Thoracic Manipulation and Special Massage Technique (RT Technique) on Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Single thoracic manipulation|OTHER: Special massage technique (RT technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DRUG: Escitalopram|DRUG: Placebo|OTHER: Rehabilitative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Smoking Cessation Interventions
Status: TERMINATED
Conditions: Smoking Cessation|Perioperative/Postoperative Complications
Interventions: BEHAVIORAL: Intervention1: Contract Agreement|BEHAVIORAL: Intervention2: Implementation Intentions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energy Balance Weight Regulation Study
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Ad libitum low carbohydrate diet|OTHER: Ad libitum High Complex Carbohydrate Diet|OTHER: Energy-restricted high complex carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism
Status: COMPLETED
Conditions: Healthy|Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: LCHF diet|DIETARY_SUPPLEMENT: LFHC diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Vegetable and Fruit Enzyme Supplementation on Muscle Activation, Aerobic Capacity, and Blood Biochemical Parameters After High-Intensity Interval Exercise: Feasibility Study of Exercise Design With Exergaming
Status: RECRUITING
Conditions: Overtraining Syndrome
Interventions: DIETARY_SUPPLEMENT: Supplementation Protocol|DIAGNOSTIC_TEST: Blood Lactate Test|DIAGNOSTIC_TEST: Training Impulse|DIAGNOSTIC_TEST: Exergaming HIIE Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism
Status: RECRUITING
Conditions: Hypoparathyroidism
Interventions: DRUG: MBX 2109|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Xeltis Bioabsorbable Pulmonary Valved Conduit Pivotal Study
Status: ENROLLING_BY_INVITATION
Conditions: Heart Defect, Congenital
Interventions: DEVICE: Xeltis Bioabsorbable Pulmonary Valved Conduit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer
Status: UNKNOWN
Conditions: Advanced or Metastatic Biliary Tract Cancer
Interventions: DRUG: MRG002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Recently Acquired Hepatitis C With the 3D Regimen or G/P
Status: COMPLETED
Conditions: Hepatitis C, Acute
Interventions: DRUG: Paritaprevir/ritonavir/ombitasvir|DRUG: Dasabuvir|DRUG: Ribavirin|DRUG: Glecaprevir/pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of Contraceptive Vaginal Ring With Different Estradiol Levels in Combination With Nestorone
Status: COMPLETED
Conditions: Suppression of Ovulation
Interventions: DEVICE: Nestorone®/Estradiol Contraceptive Vaginal Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Different Effectiveness of Single Acupoint（PC6 or CV12) vs Matching Acupoints(PC6 and CV12) in Chemotherapy-induced Nausea and Vomiting
Status: COMPLETED
Conditions: to Evaluate the Effectiveness of Acupucnture in the Management of Chemotherapy-induced Nausea and Vomiting
Interventions: OTHER: single point Neiguan(PC6) plus antiemetic drug|OTHER: single point Zhongwan(CV12) plus antiemetic drug|OTHER: matching points Neiguan(PC6) and Zhongwan(CV12) plus antiemetic drug|DRUG: only antiemetic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior-segment OCT (AS-OCT) and Intraoperative OCT (iOCT) for Trans- Conjunctival Needle Revision (TCNR)
Status: TERMINATED
Conditions: Glaucoma|Glaucoma Following Surgery
Interventions: DEVICE: Digital microscope integrated with intraoperative OCT (Zeiss Artevo 800, Carl Zeiss Meditec AG)|DEVICE: Spectralis Anterior-segment OCT (AS-OCT) (Heidelberg Engineering)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intratumoral Administration of Oncolytic Virus Injection (RT-01) in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Oncolytic Virus Injection(RT-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT