pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Promote Health With Digital Tools Among Adults With Type 2 Diabetes/Prediabetes and/or Hypertension
Status: RECRUITING
Conditions: Type 2 Diabetes|PreDiabetes|Hypertension
Interventions: BEHAVIORAL: mHealth intervention|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: N-acetylcysteine + high-dose naltrexone (150 mg)|DRUG: High-dose naltrexone (150 mg) alone|DRUG: Low-dose naltrexone (50 mg) alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: DRUG: Tislelizumab|DRUG: Capecitabine|DRUG: Oxaliplatin|RADIATION: SIB-IMRT|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnesium Supplementation on Vascular Structure and Function in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: magnesium|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bladder Preservation With Sacituzumab Govitecan + Zimberelimab for Muscle-Invasive Bladder Cancer
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|Bladder Urothelial Carcinoma|Bladder Neoplasm|Muscle-Invasive Bladder Carcinoma
Interventions: DRUG: Sacituzumab Govitecan + Zimberelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Filanesib (ARRY-520) in Combination With Pomalidomide and Dexamethasone for Relapsed/Refractory (R/R) Multiple Myeloma (MM) Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Filanesib, pomalidomide and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Digital Therapeutics of Patellofemoral Pain Syndrome Versus Usual Care
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: MORT-PFPS app|OTHER: treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Iron Chelation Therapy With Deferasirox in Patients With Transfusional Iron Overload
Status: COMPLETED
Conditions: Transfusional Iron Overload
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of PAC-14028 Cream in Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: PAC-14028 cream 0.3%|DRUG: PAC-14028 cream 1.0%|DRUG: PAC-14028 cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fat Grafting for Pedal Fat Pad Atrophy in Diabetics
Status: COMPLETED
Conditions: Pedal Pad Atrophy|Diabetes Mellitus
Interventions: PROCEDURE: Year A Pathway|PROCEDURE: Year B Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrodissection as a Treatment for Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Hydrodissection|PROCEDURE: Regular Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Problem-Solving Education for Caregivers and Patients During Stem Cell Transplant
Status: COMPLETED
Conditions: Distress|Hematopoietic Stem Cell Transplantation
Interventions: BEHAVIORAL: Problem Solving Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPROV (Improving the Radical Cure of Vivax Malaria)
Status: COMPLETED
Conditions: Uncomplicated Vivax Malaria
Interventions: DRUG: Primaquine|DRUG: Primaquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
Status: COMPLETED
Conditions: Anxiety Disorder|Cervical Cancer|Endometrial Cancer|Female Reproductive Cancer|Gestational Trophoblastic Tumor|Ovarian Epithelial Cancer|Ovarian Germ Cell Tumor|Sexual Dysfunction|Uterine Sarcoma|Vaginal Cancer|Vulvar Cancer
Interventions: OTHER: informational intervention|OTHER: counseling intervention|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing the Risk of Drug-Induced QT Interval Lengthening in Women
Status: COMPLETED
Conditions: Long QT Syndrome|Abnormalities, Drug-Induced
Interventions: DRUG: Progesterone|DRUG: Ibutilide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
Status: RECRUITING
Conditions: HER2-negative Breast Cancer|Metastatic Breast Cancer|Metaplastic Breast Carcinoma|TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: L-NMMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Genetic Studies of Congenital Myopathies
Status: RECRUITING
Conditions: Central Core Disease|Centronuclear Myopathy|Congenital Fiber Type Disproportion|Multiminicore Disease|Myotubular Myopathy|Nemaline Myopathy|Rigid Spine Muscular Dystrophy|Undefined Congenital Myopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of One-anastomosis Versus Roux-en-Y Gastric Bypass for Type 2 Diabetes Remission
Status: RECRUITING
Conditions: Type2 Diabetes|Complication of Bariatric Procedure
Interventions: PROCEDURE: The laparoscopic One-anastomosis gastric bypass will consist of:|PROCEDURE: The laparoscopic Roux-en-Y gastric bypass will consist of:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy Principles for Diabetes Prevention
Status: COMPLETED
Conditions: PreDiabetes|Diabetes Mellitus, Type 2|Diabetes|Diabetes type2
Interventions: BEHAVIORAL: Diabetes Prevention Education and Acceptance and Commitment Therapy|BEHAVIORAL: Diabetes Prevention Education Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Alpha Blockers on Prostate-specific Antigen (PSA) Change in Men With Lower Urinary Tract Symptoms (LUTS)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Prostate Cancer
Interventions: OTHER: PSA measurement, uroflowmetry, IPSS, transrectal ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gynecologic Extramammary Paget's Disease
Status: RECRUITING
Conditions: Extramammary Paget's Disease|Extramammary Paget Disease|Paget Disease, Extramammary|Extramammary Paget's Disease of Vulva (Diagnosis)|Extramammary Paget's Disease of Vagina (Diagnosis)|Extramammary Paget's Disease Vulva Invasive|Extramammary Paget's Disease of Anus (Diagnosis)|Extramammary Paget's Disease of Anal Canal (Diagnosis)|Extramammary Paget's Disease of Skin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Micro-laparoscopy and Single-port Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: micro-laparoscopy|PROCEDURE: Laparoendoscopic single site surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REVITALIZE: A Telehealth Intervention for Women With Advanced Ovarian Cancer and PARP Inhibitor-Related Fatigue
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fatigue|Coping Behavior|Coping Skills
Interventions: BEHAVIORAL: Enhanced Usual Care (EOC)|BEHAVIORAL: REVITALIZE ACT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Efficacy and Safety of QPI-1002 for Prevention of Acute Kidney Injury Following Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: QPI-1002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Digital PET/CT Using [Ga-68]PSMA vs. [F-18]NaF for Evaluation of Osseous Metastatic Involvement in Prostate Cancer Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: [68Ga]PSMA|DRUG: Flourine-18 [F-18] Sodium Fluoride (NaF)|DIAGNOSTIC_TEST: PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET Imaging of Cyclooxygenase in Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: 11C-MC1|DRUG: 11C-PS13|DRUG: Ketoprofen|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Walking Therapy In Hemiparetic Stroke Patients Using Robotic-Assisted Treadmill Training
Status: UNKNOWN
Conditions: Hemiparesis|Stroke
Interventions: DEVICE: Lokomat (Robotic Orthosis) combined with slat belt treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅱc Sutdy of Aolanti Weikang Tablets in FD PDS Patients
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Aolanti Weipang Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Assessing the Safety of Hanita Glaucoma Shunt in Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Hanita Glaucoma shunt Ver.3.2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptomatic Ascites Drainage With a Patient-controlled Vascular Catheter.
Status: RECRUITING
Conditions: Malignant Ascites
Interventions: DEVICE: Ascites drainage with vascular catheter.|BEHAVIORAL: Interview.|BEHAVIORAL: Quality of life.|DEVICE: Quality of procedure.|OTHER: Nutritional status
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DHA Supplements to Improve Insulin Sensitivity in Obese Pregnant Women (The Omega-3 Pregnancy Study)
Status: UNKNOWN
Conditions: Overweight and Obesity|Insulin Resistance|Diabetes, Gestational|Hypertension in Pregnancy|Pre-Eclampsia
Interventions: DIETARY_SUPPLEMENT: DHA Supplements|DIETARY_SUPPLEMENT: Placebo Supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trigger- vs. Substrate-Ablation for Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: trigger-guided catheter-ablation|PROCEDURE: trigger+substrate-guided catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unmet Social Needs Study
Status: COMPLETED
Conditions: Cardiovascular Disease|Hypertension|Diabetes Mellitus|Hyperlipidemia
Interventions: BEHAVIORAL: Unmet Need Screening|BEHAVIORAL: Unmet Need Referral - Resource Sheet|BEHAVIORAL: Unmet Need Referral Assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Adapalene + Clindamycin Hydrochloride|DRUG: Adapalene + Clindamycin Hydrochloride|DRUG: Adapalene + Clindamycin Hydrochloride|DRUG: Adapalene + Clindamycin Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Salt-FA to Increase Folate Levels
Status: COMPLETED
Conditions: Neural Tube Defects|Folic Acid Deficiency|Spina Bifida|Anencephaly-Spina Bifida
Interventions: DIETARY_SUPPLEMENT: Folic acid fortified iodized salt
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Geriatric Assessment and Nursing Telephone Intervention in Elderly Women With Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: BEHAVIORAL: geriatric assessment and telephone call from nurse|OTHER: geriatric assessment and no call from nurse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Removal of Uremic Toxins With Medium Cut-off and Super High-flux Vitamin E-coated Dialyzers
Status: COMPLETED
Conditions: End Stage Renal Disease (ESRD)
Interventions: DEVICE: Hemodialysis sessions using SHFVE dialyzer (VieX™) or the MCO (Theranova 500™) dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Therapy for Negative Symptoms and Functioning
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Therapy|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Nickel Sensitization After Percutaneous Implantation of Patent Foramen Ovale Occluder
Status: RECRUITING
Conditions: Foramen Ovale, Patent|Nickel Sensitivity|Dermatitis Contact Irritant|Metal Allergy
Interventions: DEVICE: Percutaneous Patent Foramen Ovale Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Advancing Prevention of Pulmonary Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: IPF|Pulmonary Fibrosis|ILD
Interventions: OTHER: Sample collection|OTHER: Questionnaires|RADIATION: High resolution CT scan of the chest|DIAGNOSTIC_TEST: Pulmonary Function Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Feasibility Study On Continuous Adaptive [18f]Fdg-Pet-Guided Radiotherapy For Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma
Interventions: OTHER: repetitive per-treatment [18F]FDG-PET for treatment adaptation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Latanoprost With Travoprost and Bimatoprost in Patients With Elevated IOP. A 12-weeks, Masked Evaluator, Phase IV Multi-center Study in the US
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: latanoprost 0.005% ophthalmic solution|DRUG: Travoprost 004% sterile ophthalmic solution|DRUG: Bimatoprost .03% sterile ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Exenatide|DRUG: Exenatide matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Patiromer on Serum Potassium Level and Gut Microbiome of ESRD Patients With Hyperkalemia
Status: COMPLETED
Conditions: ESRD|Hyperkalemia|End Stage Renal Disease
Interventions: DRUG: Patiromer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Distribution of Dapsone in Leucocytes After Single-dose and Multiple-dose Administration
Status: COMPLETED
Conditions: Methemoglobinemia|Linear IgA Bullous Dermatosis
Interventions: DRUG: Dapsone single dose|DRUG: Dapsone multiple dose|BIOLOGICAL: leucocytes|BIOLOGICAL: Met-Hb
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: WILD 5 Wellness: A 30-Day Intervention for Residents
Status: UNKNOWN
Conditions: Resident Wellness|Burnout, Professional|Medical Residents|Mental Health Wellness 1|Mental Health Disorder|Resident Physician
Interventions: BEHAVIORAL: Wellness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Udenafil Tablets in Erectile Dysfunction.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Udenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elbow Extension Restoration Surgery in People With Tetraplegia: Evolution of the Muscular Co-activations of the Upper Limb During the Post-operative Rehabilitation
Status: TERMINATED
Conditions: Tetraplegia
Interventions: OTHER: measurement of human movement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Botensilimab|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Pin Block vs Pin Orthosis-extension Block Pinning for Bonny Mallet Fractures
Status: RECRUITING
Conditions: Mallet Finger
Interventions: PROCEDURE: cextension pin block|PROCEDURE: pin orthosis- extension block pin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Self-Mediated Alternatives for Risk Testing Education and Return of Results
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: OTHER: eHealth Platform|OTHER: Videoconference Telehealth Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antioxidants vs. Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve
Status: COMPLETED
Conditions: Ovarian Reserve
Interventions: PROCEDURE: blood rich plasma platelets|DIETARY_SUPPLEMENT: Antioxidant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Amino Acid Levels After Protein Ingestion or Amino Acid Injection During Dialysis
Status: UNKNOWN
Conditions: End Stage Renal Disease on Dialysis (Diagnosis)
Interventions: DRUG: Aminoven 10%|DIETARY_SUPPLEMENT: RENORAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine How Long Restylane® Will Last After Initial Treatment With 2 Different Re-treatment Schedules.
Status: COMPLETED
Conditions: Rhytids
Interventions: DRUG: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy
Status: COMPLETED
Conditions: Drug-resistant Epilepsy|Focal-Onset Seizures
Interventions: DRUG: Padsevonil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Processing on the Measured Energy Value of Almonds in the Human Diet
Status: COMPLETED
Conditions: Healthy|Focus: Effect of Processing on Energy Value of Almonds
Interventions: OTHER: Control|OTHER: Whole Almonds|OTHER: Roasted Whole Almonds|OTHER: Diced Almonds|OTHER: Almond Butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of The Effect of Crowns Applied With Hall Technique on Occlusion
Status: COMPLETED
Conditions: Child, Only|Quality of Life
Interventions: PROCEDURE: Hall technique|PROCEDURE: Conventional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DNX-2440 for Resectable Colorectal Liver Metastasis
Status: SUSPENDED
Conditions: Liver Metastases|Liver Metastasis Colon Cancer|Colorectal Cancer|Breast Cancer|Gastric Cancer|Periampullary Cancer|Melanoma|Renal Cell Cancer|Sarcoma|Squamous Cell Carcinoma|Gastrointestinal Stromal Tumors
Interventions: BIOLOGICAL: DNX-2440
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour
Status: NOT_YET_RECRUITING
Conditions: Leiomyosarcoma Uterus
Interventions: DRUG: Doxorubicin|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study to Evaluate the Safety and Efficacy of PerioSept® as Adjunct to SRP in Subjects With Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: PerioSept(r)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate|DRUG: vindesine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GK1-399 (formerly TTP399)|DRUG: GK1-399 (formerly TTP399)|DRUG: GK1-399 (formerly TTP399)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Identification Badge on Situation Awareness During High Fidelity Simulation
Status: COMPLETED
Conditions: Patient Simulation|Awareness|Reality Testing|Residency
Interventions: OTHER: Use of identification badge during scenarios
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Efficacy of Zinc-biofortified Rice in Bangladeshi Children
Status: COMPLETED
Conditions: Zinc Deficiency|Growth; Stunting, Nutritional
Interventions: DIETARY_SUPPLEMENT: Intervention-group|DIETARY_SUPPLEMENT: Control-group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Alogliptin Used in Combination With α-glucosidase Inhibitor in Participants With Type 2 Diabetes in Japan
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin and voglibose|DRUG: Alogliptin and voglibose|DRUG: Voglibose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Fluorouracil|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diet on Quality of Life in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DIETARY_SUPPLEMENT: BodyBio Balance Oil|DIETARY_SUPPLEMENT: Kirunal Fish Oil|DIETARY_SUPPLEMENT: BodyBio PC|BEHAVIORAL: Modified Paleolithic Elimination diet|BEHAVIORAL: Time Restricted Olive Oil Based (TROO) Ketogenic Diet|BEHAVIORAL: Usual diet with Dietary Guidelines for Americans Diet information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fospropofol for Sedation During Elective Awake Intubation
Status: WITHDRAWN
Conditions: Impaired Airway Clearance
Interventions: DRUG: fospropofol|DRUG: fospropofol|DRUG: fospropofol|DRUG: fospropofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Crossover Study With MultiHance vs a Comparator for Peripheral MRA
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DRUG: MultiHance|DRUG: Magnevist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vetal Laban Intervention Trial Assessing Bowel Symptoms
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Vetal Laban active|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Safety of Hib-MenCY-TT Vaccine Versus Licensed Hib Conjugate Vaccine, Given at 12 to 15 Months of Age.
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Neisseria Meningitidis
Interventions: BIOLOGICAL: GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine combined (792014)|BIOLOGICAL: PedvaxHIB|BIOLOGICAL: Prevnar|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Active Young, Healthy Mind. The YoungFitT Project
Status: RECRUITING
Conditions: University Students
Interventions: BEHAVIORAL: High-Intensity Functional Training (HIFT)|BEHAVIORAL: Mindfulness-Based Stress Reduction Program (MBSR)|BEHAVIORAL: Qigong
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EEG and Pharmacological Exploration of Executive Dysfunctions Induced by STN-DBS in PD
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Clonidine (Catapressan)|DEVICE: Placebo 90 minutes before EEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Melatonin|OTHER: Placebo (Methylcellulose) capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Vixarelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Irritable Bowel Syndrome Patients
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DEVICE: Acupuncture|DEVICE: Sham-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Entospletinib (ENTO [GS-9973]) Combined With Vincristine (VCR) in Adult Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NHL)
Status: TERMINATED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Entospletinib|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up Study to Evaluate Safety and Immunogenicity of PXVX0317 Single or Booster Vaccination
Status: RECRUITING
Conditions: Chikungunya Virus Infection
Interventions: BIOLOGICAL: CHIKV VLP vaccine booster|BIOLOGICAL: Placebo booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade Glioma
Status: COMPLETED
Conditions: Adult Diffuse Astrocytoma|Adult Mixed Glioma|Adult Oligodendroglioma|Recurrent Adult Brain Tumor|Adult Oligoastrocytoma
Interventions: BIOLOGICAL: tumor lysate-pulsed autologous dendritic cell vaccine|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressive Muscle Relaxation Exercises Women With Low Sexual Satisfaction Sexual Satisfaction and Functioning of Women and Their Partners
Status: COMPLETED
Conditions: Women With Low Sexual Satisfaction|Partners of Women With Low Sexual Satisfaction
Interventions: BEHAVIORAL: Progressive Muscle Relaxation Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rebeccamycin Analog and Oxaliplatin in Treating Patients With Refractory Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: becatecarin|DRUG: oxaliplatin|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial
Status: TERMINATED
Conditions: Peripheral Endovascular Interventions|Bleeding
Interventions: DRUG: Bivalirudin|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy With Cellistem-OA for Symptomatic Knee Osteoarthritis
Status: UNKNOWN
Conditions: Mesenchymal Stem Cells|Knee Osteoarthritis|Cell Therapy
Interventions: BIOLOGICAL: CELLISTEM-OA|DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: DRUG: Sodium fluoride (1426 ppm)|DRUG: Sodium fluoride (1150 ppm)|DRUG: Sodium fluoride (250 ppm)|DRUG: Sodium fluoride (1426 ppm) + zinc base A|DRUG: Sodium fluoride (1426 ppm) + zinc base B|DRUG: Fluoride (0 ppm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Trial (MVA-BN-Brachyury/FPV-Brachyury)
Status: COMPLETED
Conditions: Safety Issues
Interventions: BIOLOGICAL: MVA-BN-Brachyury/ FPV-Brachyury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of BMS-770767 in Subjects With Hypercholesterolemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: BMS-770767|DRUG: BMS-770767|DRUG: BMS-770767|DRUG: BMS-770767|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switch to TAF+FTC+BIC in HIV-1-infected Patients Over 65 Years Old at Risk of Polymedication
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: BIKTARVY 50Mg-200Mg-25Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Triple-therapy Using Boceprevir in HIV-positive Patients With Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic|HIV
Interventions: DRUG: Pegylated interferon alpha-2a|DRUG: Ribavirin|DRUG: Boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Sensory Discrimination
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DEVICE: Direct Current Stimulation|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer|Peritoneal Carcinomatosis|Fallopian Tube Cancer
Interventions: DRUG: Recombinant oncolytic herpes simplex virus type 1 (R130)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Atorvastatin and Rosuvastatin in Reduction of Inflammatory Biomarkers in Patients With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Mi Q Wave
Interventions: DEVICE: Turbox CRP kit|DRUG: rosuvastatin 20 mg,|DRUG: atorvastatin 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter
Status: COMPLETED
Conditions: Cervical Cancer|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous/Nonmalignant Condition|Unspecified Adult Solid Tumor, Protocol Specific|Veno-occlusive Disease
Interventions: DRUG: Fragmin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Circuit Training on Vertigo, Oscillopsia and Dizziness in Vestibular Hypo Function Hypo- Functions
Status: COMPLETED
Conditions: Vestibular Disorder
Interventions: OTHER: Experimental|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xylitol Based Nasal Spray for COVID-19 Treatment
Status: NOT_YET_RECRUITING
Conditions: Respiratory Viral Infection
Interventions: DEVICE: Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Upper Limb Kinematics in Children With Cerebral Palsy After Lower Limb Surgery
Status: COMPLETED
Conditions: Cerebral Palsy|Gait Analysis|Gait Disorders, Neurologic|Gait Disorders in Children
Interventions: OTHER: Cerebral palsy Gait analysis technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of ExoFlo for the Treatment of Perianal Fistulas
Status: ACTIVE_NOT_RECRUITING
Conditions: Perianal Fistula|Crohn's Disease
Interventions: BIOLOGICAL: ExoFlo|OTHER: Local injection of normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
Status: RECRUITING
Conditions: Schizophrenia|Schizophreniform Disorder|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Aerobic Exercise Program|BEHAVIORAL: Moderated Online Social Therapy (MOST)|BEHAVIORAL: Chorus Participatory Text Messaging Program|BEHAVIORAL: Healthy Living Group (HLG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-Arm Study Comparing the Analgesic Efficacy and Safety of Acetaminophen and Tramadol Combination BID Versus Placebo for the Treatment of Acute Low Back Pain
Status: COMPLETED
Conditions: Acute Low Back Pain
Interventions: DRUG: Combination drug (Acetaminophen + Tramadol)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Estimation of Doses Delivered During Image Guided Radiation Therapy Tests
Status: NOT_YET_RECRUITING
Conditions: Lung Neoplasm|Pelvic Neoplasm|Breast Cancer|Cancer, Otorhinolaryngeal|Cancer Pediatric
Interventions: OTHER: 3D maps of physical doses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gabapentin as Adjuvant for Postoperative Pain in Pediatric Orthopedic Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Orthopedic Disorder
Interventions: DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia
Status: COMPLETED
Conditions: Spasticity|Focal Dystonia|Tremor, Limb
Interventions: DEVICE: Electrical stimulation|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: INS018_055|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: DEVICE: Trilogy Lithotrite|DEVICE: The ShockPulse-SE Lithotripsy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy in Children
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy, Obstructive
Interventions: PROCEDURE: Percutaneous intramyocardial septal radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Person-Centered Psychosis Care: An Educational Intervention
Status: COMPLETED
Conditions: Patient-Centered Care|Psychiatry|Inpatient|Psychosis
Interventions: BEHAVIORAL: Person-centered psychosis care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transition of Single Surgeon Bariatric Service to an Interdisciplinary Multiple Surgeon Model
Status: COMPLETED
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: PROCEDURE: Bariatric surgery- single surgeon service|PROCEDURE: Bariatric surgery- multiple surgeon + multidisciplinary team approach|PROCEDURE: Bariatric surgery: formalized streamlined multiple surgeon + multidisciplinary team approach
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flexible Insulin Therapy Untethered Insulin Regimen in Avidly Exercising Patients With Type 1 Diabetes: FIT Untethered
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology
Status: NOT_YET_RECRUITING
Conditions: Radiosensitivity|Pediatric Cancer|Radiation Toxicity
Interventions: BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics of Two Fatty Acid Ketone Esters
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: C6 ketone di-ester|DIETARY_SUPPLEMENT: Novel ketone di-ester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic and Efficacy of SQV/r 1500/100 Plus Tenofovir/Emtricitabine 300/200 mg
Status: WITHDRAWN
Conditions: Saquinavir/Ritonavir BID or Lopinavir/Ritonavir BID
Interventions: DRUG: saquinavir/ritonavir plus truvada
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous)
Status: RECRUITING
Conditions: Implantable Defibrillator User|Hypertrophic Cardiomyopathy|Implantable Cardioverter Ventricular Lead Dysfunction or Complication|Ventricular Arrythmia
Interventions: DEVICE: Implantable Cardioverter Defibrillator implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rabies Virus Neutralizing Activity and Safety of CL184, a Monoclonal Antibody Cocktail, in Simulated Rabies Post-Exposure Prophylaxis in Healthy Adults
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Rabies virus-specific monoclonal antibodies|BIOLOGICAL: human polyclonal rabies immune globulin (HRIG)|BIOLOGICAL: Placebo|BIOLOGICAL: Human diploid cell vaccine (HDCV)|BIOLOGICAL: Purified verocell rabies vaccine (PVRV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Erlotinib HCl (OSI-774)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: High-resolution Imaging of Corneal Lesions With Optical Coherence Tomography (OCT) - A Pilot Study
Status: COMPLETED
Conditions: Corneal Abrasions|Corneal Infiltrates
Interventions: DEVICE: Optical Coherence Tomography (OCT)|OTHER: Slit lamp biomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Artery Disease
Interventions: COMBINATION_PRODUCT: Percutaneous Transluminal Angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT