pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload
Status: COMPLETED
Conditions: Transfusional Iron Overload in β-thalassemia
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial With Subcutaneous Immunotherapy in Depot Presentation in Patients With Rhinoconjuncitivis Sensitized to Olea Europaea
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: BIOLOGICAL: Allergovac depot with Olea europaea pollen extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pacritinib Combined With Decitabine or Cytarabine in Older Patients With AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Pacritinib|DRUG: Decitabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab Plus Ipilimumab in Patients With Unresectable Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Bevacizumab Plus Ipilimumab Cohort 1|DRUG: Bevacizumab Plus Ipilimumab Cohort 2|DRUG: Bevacizumab Plus Ipilimumab Cohort 3|DRUG: Bevacizumab Plus Ipilimumab Cohort 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Interferon Beta-1a (Avonex®) on Changes of Non-conventional MRI Measures in Patients With MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Avonex® monotherapy (6.0 MIU administered i.m. each week)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Chronic Chagas Disease
Interventions: DRUG: benznidazole 300 mg daily 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Childbirth and Parenting Education on Pregnant Women
Status: UNKNOWN
Conditions: Stress, Psychological|Pregnancy Related
Interventions: BEHAVIORAL: MBCP education|BEHAVIORAL: Hospital-based antenatal education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photobiomodulation Protocols in the Analgesia of Chemotherapy-induced Oral Mucositis in Children
Status: RECRUITING
Conditions: Mucositis Oral
Interventions: RADIATION: LLLT applied every other day|RADIATION: LLLT applied daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage II Non-Small Cell Lung Cancer AJCC v7|Stage IIA Non-Small Cell Lung Carcinoma AJCC v7|Stage IIB Non-Small Cell Lung Carcinoma AJCC v7|Stage III Non-Small Cell Lung Cancer AJCC v7|Stage IIIA Non-Small Cell Lung Cancer AJCC v7|Stage IIIB Non-Small Cell Lung Cancer AJCC v7
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|BIOLOGICAL: Durvalumab|DRUG: Etoposide|DRUG: Paclitaxel|DRUG: Pemetrexed Disodium|RADIATION: Photon Beam Radiation Therapy|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of BDL(Bedaquiline Plus Delamanid Plus Linezolid) Regimen in Subjects With Pulmonary Infection of Multi-drug Resistant Tuberculosis (MDR-TB) or Rifampicin-Resistant Tuberculosis (RR-TB)
Status: RECRUITING
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: BDL regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome
Status: WITHDRAWN
Conditions: Obesity Hypoventilation Syndrome
Interventions: DEVICE: Breas Vivo 40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of Working Length Determination by Electronic Apex-Locator or Radiography on Adequacy of Final Working Length
Status: UNKNOWN
Conditions: Root Canal
Interventions: DEVICE: Electronic Apex Locator|DEVICE: Dental Radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Cognitive Exercise Therapy Approach in Patients With Primary Sjögren's Syndrome
Status: RECRUITING
Conditions: Primer Sjogren's Syndrome
Interventions: OTHER: Cognitive Exercise Therapy Approach (BETY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SG301-SC Injection Safety Study in Subjects With Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: SG301 SC Injection|DRUG: SG301 SC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tooth Borne Versus Temporary Anchorage Devices (TAD) Based Intrusion Systems for the Correction of Anterior Deep Overbite
Status: COMPLETED
Conditions: Deep Overbite
Interventions: DEVICE: Intrusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes
Status: RECRUITING
Conditions: To Determine the Levels of miRNA1 and miRNA133a Before and After Exercise
Interventions: OTHER: miRNA levels analysis from saliva samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperatively Orientation in Cardiac Surgery: Nurses Intervention on Patients Recovery
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Triple Vessel|Heart Valve Diseases
Interventions: OTHER: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of the Metabolism and Pharmacokinetics of 10 mg [14C] BI 1356 Administered Orally Compared to 5 mg [14C] BI 1356 Administered Intravenously in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C] BI 1356 as oral (p.o.) solution|DRUG: [14C] BI 1356 solution for i.v. infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Versus Continuous Pulse Oximetry Monitoring of Infants Admitted for Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis|Hypoxia
Interventions: OTHER: Continuous pulse oximetry monitoring|DEVICE: Intermittent pulse oximetry monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Slow and Low Start of a Tacrolimus Once Daily Immunosuppressive Regimen
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Failure|Renal Insufficiency|Renal Disease|Renal Insufficiency, Chronic
Interventions: DRUG: Advagraf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Single Dose Of ATN-103 Administered To Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103|DRUG: ATN-103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic
Status: NOT_YET_RECRUITING
Conditions: Pruritis
Interventions: DRUG: Dupilumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the Lung
Status: COMPLETED
Conditions: Melanoma (Skin)|Metastatic Cancer
Interventions: BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trigger Point Injections Versus Lidocaine Patch for Myofascial Pain in the Emergency Department
Status: RECRUITING
Conditions: Myofascial Trigger Point Pain|Myofacial Pain
Interventions: PROCEDURE: Trigger point injection with 1% lidocaine|DRUG: Lidocaine patch 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3819253 (LY-CoV555) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3819253|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device
Status: COMPLETED
Conditions: Wrinkles|Fine Lines|Crepey Skin|Acne Scars|Active Acne|Enlarged Pores|Loose Skin
Interventions: DEVICE: RF Device (Potenza™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Gaming Adherence Program for Youth Living With HIV
Status: COMPLETED
Conditions: Adherence to HIV Treatment and Medication
Interventions: BEHAVIORAL: IMB Gaming Adherence Intervention|BEHAVIORAL: Enhanced treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-polar RF and PEMF for Treatment of Symptoms Associated With Vulvovaginal Atrophy
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DEVICE: Venus Fiore Study Treatment|DEVICE: Venus Fiore Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy for Smoking Cessation: Pilot
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DEVICE: Auriculotherapy using TENS unit Stim Flex 400A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Neutrophil Gelatinase-associated Lipocalins (NGAL) and Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|CKD|NGAL|Neutrophil Gelatinase-associated Lipocalin|Emergency Department|AKI|Acute Kidney Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Efficacy and Safety of Umeclidinium/Vilanterol With Fluticasone Propionate/Salmeterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UMEC/VI Inhalation Powder 62.5/25 mcg via NDPI|DRUG: FSC Inhalation Powder 250/50 mcg via ACCUHALER/DISKUS|DRUG: Placebo DISKUS|DRUG: Placebo NDPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Drospirenone-containing or -Not Containing Combined Oral Contraceptives on General and Sexual Well-being
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: EE30-DRSP (Yasmin, BAY86-5131)|DRUG: Other combined oral contraceptives
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Community Building Through Virtual, Team-Based Exercise on Burnout
Status: COMPLETED
Conditions: Burnout, Professional|Burnout, Student|Community Building|Mentorship|Exercise
Interventions: BEHAVIORAL: First 3 months of virtual, team-based exercise|BEHAVIORAL: Second 3 months of virtual, team-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Atomoxetine and OROS Methylphenidate to Treat Children and Adolescents Ages 6-17 With ADHD
Status: COMPLETED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine and OROS Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2)
Status: COMPLETED
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: obinutuzumab|DRUG: rituximab|DRUG: chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Mechanism of Action of an Oral Enzyme Treatment With Bromelain, Trypsin and Rutoside Versus Placebo in Subjects With OsTeoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Wobenzym®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease
Status: RECRUITING
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Different Protocol in Wrist Joint Limitation After Distal Radius End Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture|Wrist Fracture
Interventions: OTHER: Exercise|OTHER: PNF Technique|OTHER: Mulligan Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Proton Therapy for High Risk Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: Radiation therapy (XRT)|OTHER: Androgen Deprivation Therapy (ADT)|OTHER: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
Status: COMPLETED
Conditions: Spinal Cord Injuries|Tetraplegia|Quadriplegia
Interventions: DEVICE: Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: ESP Versus PIFB for Analgesia in Open Cardiac Surgery: a Randomized Control Trial
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Erector spinae plane block (ESPB)|PROCEDURE: Pecto-intercostal fascial plane blok (PIFB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Bolus Recombinant Nonimmunogenic Staphylokinase (FORtelyzin) Versus Single Bolus Tenecteplase (Metalyse) in STEMI
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Recombinant staphylokinase|DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Equivalence of Two Butenafine Hydrochloride 1% Creams in Patients With Interdigital Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Butenafine cream 1% manufactured by Taro|DRUG: Lotrimin Ultra (butenafine) 1%|DRUG: Butenafine Vehicle manufactured by Taro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screw-retained Maxillary Complete Denture With Electric Welded Metal Framework Versus Cast One, Patient Satisfaction Assessment.
Status: UNKNOWN
Conditions: Patient Satisfaction|Maintenance
Interventions: DEVICE: Electric Welded Metal Framework
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Postoperative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Electronic Moxibustion Apparatus on Pain Degree and Wound Healing of Patients After Craniocerebral Surgery
Status: NOT_YET_RECRUITING
Conditions: Patients Undergoing Craniocerebral Surgery
Interventions: DEVICE: electronic moxibustion apparatus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BYL719 + T-DM1 in HER2(+) Metastatic Breast Cancer Pts Who Progress on Prior Trastuzumab & Taxane Tx
Status: COMPLETED
Conditions: HER2-positive Breast Cancer|Recurrent Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: PI3K inhibitor BYL719|BIOLOGICAL: ado-trastuzumab emtansine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients
Status: NOT_YET_RECRUITING
Conditions: Alcohol-related Liver Disease|Liver Diseases
Interventions: BEHAVIORAL: ENGAGE-ALD Application (APP)|BEHAVIORAL: Treatment Facilitation bundle|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Types of PRP in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthrosis
Interventions: BIOLOGICAL: Platelets Rich Plasma|BIOLOGICAL: Leucocyte - Platelets Rich Plasma|DRUG: Hialuronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria
Status: TERMINATED
Conditions: Malaria
Interventions: DRUG: Pyronaridine - artesunate|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Study
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: BIOLOGICAL: Fluzone® Intradermal Vaccine|BIOLOGICAL: Fluzone® (Intramuscular) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VX-445/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients Heterozygous for F508del Mutation and a Minimal Function Mutation (F/MF Genotypes)
Status: APPROVED_FOR_MARKETING
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: EXPANDED_ACCESS
Clinical trial: Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment Prostate Cancer
Status: RECRUITING
Conditions: Oligometastatic Prostate Carcinoma|Prostate Adenocarcinoma
Interventions: DRUG: Abiraterone Acetate|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Gonadotropin-releasing Hormone Analog|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abatacept in Patients With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: abatacept (ABA)|DRUG: placebo|DRUG: abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Nutrient Supplement in COPD (NUTRECOVER-trial)
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DIETARY_SUPPLEMENT: Targeted nutrient supplementation (Long-drink)|DIETARY_SUPPLEMENT: Placebo supplement|BEHAVIORAL: Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved
Status: UNKNOWN
Conditions: Colorectal Cancer Metastatic|Survival Rate|General Anesthetics Toxicity|Lymphocyte Destruction|Molecular Mechanism of Pharmacological Action
Interventions: DRUG: Propofol|DRUG: Sevoflurane|DRUG: Remifentanil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine
Status: COMPLETED
Conditions: Guillain-Barre Syndrome
Interventions: DRUG: 4-aminopyridine (4-AP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS)
Status: UNKNOWN
Conditions: Bone Loss|Muscle Atrophy|Bariatric Surgery
Interventions: DRUG: Zoledronic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Working Towards Empowered Community-driven Approaches to Increase Vaccination and Preventive Care Engagement
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19
Interventions: OTHER: mHealth Outreach|OTHER: Care Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Propranolol Plus Sunitinib in First-line Treatment of Metastatic Renal Cell Carcinoma
Status: WITHDRAWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Propranolol|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics Pharmacodynamics of SHR-2010 by Intravenously/Subcutaneously in Healthy Subject
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: SHR-2010 injection|DRUG: SHR-2010 injection placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention-Deficit / Hyperactivity Disorder|Depression|Obesity
Interventions: BEHAVIORAL: Bright light therapy|BEHAVIORAL: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adaptive Cognitive Training in Healthy Older Adults
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Mild to Moderate Dementia|Alzheimer's Disease
Interventions: OTHER: Computerized cognitive training|OTHER: Computerized games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Meditation-Based Breathing Training in Improving Target Motion Management and Reducing Distress in Patients With Abdominal or Lung Cancer Undergoing Radiation Therapy
Status: TERMINATED
Conditions: Anxiety|Depression|Digestive System Neoplasm|Lung Neoplasm|Pain|Post-Traumatic Stress Disorder|Psychological Impact of Cancer
Interventions: OTHER: Educational Intervention|OTHER: Meditation Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Copeptin Levels in Elective Cesarean Section With Different Anesthetic Technique
Status: COMPLETED
Conditions: Fetal Distress
Interventions: OTHER: Copeptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of EQ101 in Adult Subjects With Moderate to Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata|Alopecia|Alopecia Totalis|Alopecia Universalis
Interventions: DRUG: EQ101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Astaxanthin in Volunteer With Refraction Errors
Status: UNKNOWN
Conditions: Refractive Errors
Interventions: DIETARY_SUPPLEMENT: astaxanthin 4 mg|DIETARY_SUPPLEMENT: astaxanthin 6 mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotics for Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders|Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: placebo followed by Lactobacillus plantarum MF 1298|DIETARY_SUPPLEMENT: Lactobacillus plantarum MF1298 followed by placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic Scarring
Status: NOT_YET_RECRUITING
Conditions: Burns|Hypertrophic Scar
Interventions: DEVICE: 3D scan measurment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study of Anterior Tibial Translation Measurement by Four Laximeters in Anterior Cruciate Ligament Ruptures
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Laximeter measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stromal Vascular Fraction for Treatment of Xerostomia
Status: WITHDRAWN
Conditions: Xerostomia Due to Radiotherapy (Disorder)
Interventions: BIOLOGICAL: Stromal Vascular Fraction|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-663513 in Combination With Chemoradiation in Subjects With Non Small Cell Lung Carcinoma (NSCLC)
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: BMS-663513
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-defining Memories in Patients With a TBI
Status: COMPLETED
Conditions: Traumatic Brain Injuries|Neurobehavioral Manifestations|Cognition Disorders|Memory Deficits
Interventions: OTHER: Questionnaires and cognitive measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Non-Hodgkin's Lymphoma
Interventions: DRUG: Fenretinide|DRUG: Cytarabine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Pharmacodynamic Profiles and Safety After Oral Administration of Ivabradine in Male Healthy Korean Volunteers
Status: COMPLETED
Conditions: Healthy Individual
Interventions: DRUG: Ivabradine and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Arthroscopy in Patients Undergoing Wrist Fracture
Status: UNKNOWN
Conditions: Wrist Injuries
Interventions: DEVICE: arthroscopy + volar plate|DEVICE: Volar plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy Study of PROTOXIN in Subjects With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: PROTOXIN|BIOLOGICAL: Botox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema
Status: ACTIVE_NOT_RECRUITING
Conditions: Corneal Edema|Corneal Endothelial Dysfunction|Corneal Endothelial Dystrophy|Fuchs Dystrophy|Fuchs Endothelial Corneal Dystrophy|Pseudophakic Bullous Keratopathy|Bullous Keratopathy|Endothelial Dysfunction|Moderate Corneal Endothelial Decompensation
Interventions: BIOLOGICAL: EO2002|BIOLOGICAL: EO2002 low dose|BIOLOGICAL: EO2002 mid dose|BIOLOGICAL: EO2002 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Infusions of Fluorouracil in Treating Patients With Dukes' A, Dukes' B, or Dukes' C Colon Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|OTHER: Observation|DRUG: sodium heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ozone Therapy for Masticatory Muscle Pain (OTMMP)
Status: UNKNOWN
Conditions: Orofacial Pain|Temporomandibular Joint Disorders
Interventions: DEVICE: Ozone|DEVICE: Placebo (for Ozone)|DEVICE: Dental treatment with occlusal splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Value of Applying TOF and TcPO2 to Guide Elderly Patients Extubation
Status: UNKNOWN
Conditions: Postoperative Respiratory Complications
Interventions: OTHER: TOF unit TcPCO2 group|OTHER: TOF group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ADASUVE 2-dose Thorough QT/QTc Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ADASUVE 10 mg 2 doses 2 hours apart|DRUG: Inhaled Placebo|DRUG: Oral moxifloxacin 400 mg|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparing the Quality of Analgesia With Pectoral Nerve Block and Serratus Plane Block in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Mastectomy|Breast Cancer
Interventions: PROCEDURE: PECS block, SAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: DP303c in Patients With HER2-positive Unresectable Locally Advanced, Relapsed, or Metastaticbreast Cancer
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: DP303c
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Preconditioning on Children Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Cyanosis
Interventions: OTHER: RIPC (remote ischemic preconditioning)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Investigate The Pharmacokinetics Of Intravenous WCK 5222 (FEP-ZID) In Patients With Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: WCK 5222
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Spinal Navigation Trial - Surgical Navigation or Free Hand Technique in Spine Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Scoliosis|Kyphosis
Interventions: PROCEDURE: Pedicle screws insertion by free hand technique|PROCEDURE: Pedicle screws insertion using ARSN|PROCEDURE: Pedicle screws insertion using IRSN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension (PAH)
Interventions: DEVICE: Magnetic Resonance Imaging (MRI) with exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: sargramostim|BIOLOGICAL: therapeutic autologous dendritic cells|BIOLOGICAL: trastuzumab|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: 10% lidocaine spray|DRUG: Placebo of lidocaine spray|DRUG: Cisatracurium|DRUG: Placebo of cisatracurium|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
Status: RECRUITING
Conditions: Depression|Anterior Cruciate Ligament Injuries|Mental Health Issue
Interventions: BEHAVIORAL: Virtual Psychological Intervention: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Evaluation of a Restorative Glass Ionomer and a Composite Resin for the Restoration
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Disease
Interventions: DEVICE: Fuji Bulk|DEVICE: G-ænial Posterior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Natriuretic Peptides After Left Atrial Appendage Amputation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: LAA amputation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Hyperandrogenemia and Altered Day-night LH Pulse Patterns
Status: RECRUITING
Conditions: Hyperandrogenism|Polycystic Ovary Syndrome|Puberty
Interventions: DRUG: Micronized progesterone|DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interbody Spacers With map3® Cellular Allogeneic Bone Graft in Anterior or Lateral Lumbar Interbody Fusion
Status: COMPLETED
Conditions: Spondylosis|Spondylolisthesis|Degenerative Disc Disease
Interventions: OTHER: map3® Cellular Allogeneic Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Status: RECRUITING
Conditions: Transplant;Failure,Kidney|Transplant; Failure, Liver|Adherence, Medication|Adherence, Patient|Adherence, Treatment
Interventions: BEHAVIORAL: mHealth Messaging Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19
Status: COMPLETED
Conditions: Covid19|Sars-CoV2
Interventions: PROCEDURE: Ophthalmologic exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenylalanine, Methionine and Histidine Requirements in TPN Fed Neonates
Status: RECRUITING
Conditions: Stable Neonates|Receiving Total Parenteral Nutrition (TPN)
Interventions: DRUG: Total parenteral nutrition (TPN). This is total nutrition provided by central vein.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Induction and Maintenance Study of BMS-936557 Patients With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: Anti-IP-10 Antibody|DRUG: Anti-IP-10 Antibody|DRUG: Anti-IP-10 Antibody|DRUG: Anti-IP-10 Antibody|DRUG: Anti-IP-10 Antibody|DRUG: Anti-IP-10 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Nerve Stimulation on Cognitive Function and Upper Limb Motor Function in People With Chronic Stroke
Status: RECRUITING
Conditions: Chronic Stroke
Interventions: DEVICE: spine TENS|DEVICE: tVNS|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Paclitaxel|DRUG: Copanlisib (BAY80-6946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Central Venous Oxygen Saturation Assisted Intraoperative Hemodynamic Management
Status: COMPLETED
Conditions: Major Abdominal Surgery|Perioperative Haemodynamic Monitoring|Perioperative Fluid Management|Perioperative Vasopressor Requirement|Postoperative Organ Function|Postoperative Complications
Interventions: DEVICE: CeVOX|DEVICE: CVP|DRUG: Fluid bolus|DRUG: Vasopressor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Raltegravir-based Antiretroviral Therapy for Resistant HIV-1 Infection
Status: UNKNOWN
Conditions: AIDS/HIV PROBLEM
Interventions: DRUG: RAL+TDF+LPV/r|DRUG: 3TC+TDF+LPV/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Status: RECRUITING
Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Bleomycin Sulfate|DRUG: Brentuximab Vedotin|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Dacarbazine|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Etoposide Phosphate|OTHER: Fludeoxyglucose F-18|RADIATION: Involved-site Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|DRUG: Prednisolone|DRUG: Prednisone|DRUG: Procarbazine Hydrochloride|OTHER: Questionnaire Administration|DRUG: Vinblastine Sulfate|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MG-K10 in Subjects With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: MG-K10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety of HBM9161 (HL161) Subcutaneous Injection in Patients With Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: HBM9161 Injection (680mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Tumor Lysis Syndrome
Interventions: DRUG: Pegloticase|DRUG: Rasburicase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety/Efficacy of Asacol® Given Every 12 Hours to Children and Adolescents With Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Asacol 400 mg|DRUG: Asacol 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With IPAA
Status: COMPLETED
Conditions: Pouchitis|Irritable Pouch Syndrome
Interventions: DIETARY_SUPPLEMENT: SBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NeO2Matic-Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Pre-Term|Respiratory Distress Syndrome, Newborn|Retinopathy of Prematurity|Bronchopulmonary Dysplasia
Interventions: DEVICE: O2Matic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six-week, Randomized, Double-blind, Placebo-controlled, Parallel Group, Multi-center, Phase II Study
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: BL - 1020|DRUG: BL - 1020|DRUG: Placebo|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of GE-145 320 mg I/mL Injection vs. Iopamidol 370 mg I/mL in Elderly Subjects Undergoing Coronary Procedure
Status: COMPLETED
Conditions: Chronic Renal Insufficiency|Diabete Mellitus|Congestive Heart Failure
Interventions: DRUG: GE-145
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Project Impact: An Innovative Approach to Weight Loss Maintenance
Status: COMPLETED
Conditions: Obesity|Weight Loss|Overweight
Interventions: BEHAVIORAL: Gold Standard Behavior Therapy for Weight Loss|BEHAVIORAL: Behavior Therapy for Weight Loss with Physical Activity Emphasis|BEHAVIORAL: Acceptance-based Behavior Therapy for Weight Loss with PA emphasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Neoantigen Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy
Status: RECRUITING
Conditions: Resectable Pancreatic Cancer
Interventions: BIOLOGICAL: iNeo-Vac-P01|OTHER: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: Moderate Procedural Sedation with a sedative medication.|PROCEDURE: Deep Procedural Sedation with a sedative medication.|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT