pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of the Safety and Effectiveness of LGH447 and BYL719 in Patients With Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: DRUG: LGH447|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of the Implantation of a New Electrode for the Treatment of Dystonia
Status: TERMINATED
Conditions: Generalized Dystonia|Segmental Dystonia|Tardive Dystonia
Interventions: DEVICE: Electrode deep brain stimulation (Monopolar DBS Lead Model 09064-40cm)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function
Status: UNKNOWN
Conditions: Glaucoma
Interventions: PROCEDURE: Argon laser Iridoplasty|DRUG: Intravenous acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mesenchymal Stem Cell for Radiation-induced Hyposalivation and Xerostomia in Previous Head and Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Xerostomia Following Radiotherapy
Interventions: BIOLOGICAL: Stem cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BMB-101 in Absence Epilepsy and DEE
Status: NOT_YET_RECRUITING
Conditions: Absence Epilepsy|Jeavons Syndrome|Dravet Syndrome|Lennox Gastaut Syndrome
Interventions: DRUG: BMB-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Mechanical Ventilation Complication|Sedation Complication
Interventions: DRUG: Propofol|DRUG: Isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: IMAGINE Study Protocol
Status: UNKNOWN
Conditions: Patients (>=60 Years Old) Suffering From Mild-moderate Stroke (Ischemic or Hemorrhagic, Stroke Severity Assessed by NIHSS <16 Points)
Interventions: BEHAVIORAL: Motivational interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of BAY 59-8862 in Taxane Resistant Non-Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BAY59-8862 (Cytotoxic Taxane)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How a New Pneumococcal Vaccine Works in Children
Status: RECRUITING
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: PG4|BIOLOGICAL: 20-valent pneumococcal conjugate vaccine (20vPnC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 177Lu-PSMA-R2 in Patients With PSMA Positive Progressive, Metastatic, Castration Resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasm
Interventions: DRUG: 177Lu-PSMA-R2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Agency and Threat-Immediacy in Interactive Digital Narrative Fear Appeals
Status: COMPLETED
Conditions: Excessive Drinking
Interventions: OTHER: High agency and immediate threat|OTHER: High agency and distant threat|OTHER: Low agency and immediate threat|OTHER: Low agency and distant threat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Laparscopic Hernioplasty in Recurrent Inguinal Hernia
Status: COMPLETED
Conditions: Recurrent Inguinal Hernia
Interventions: PROCEDURE: Transabdominal preperitoneal (TAPP) using polyprolene mesh|PROCEDURE: Total extraperitoneal (TEP) hernioplasty using polyprolene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations
Status: RECRUITING
Conditions: Advance Care Planning|Advance Directives|Terminal Illness|Chronic Illness|Communication
Interventions: BEHAVIORAL: Hello (serious game)|BEHAVIORAL: The Conversation Project (CP) Starter Kit|OTHER: Table Topics (general conversation game)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Virtual Reality's Effect on Decreasing Pain and Subsequent Opioid Use in Pediatric Patients in the Post-Operative Period Following Scoliosis Repair
Status: RECRUITING
Conditions: Scoliosis; Juvenile|Scoliosis; Adolescence|Scoliosis
Interventions: DEVICE: virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Tolerance Study of B-DYN Versus Conventional Fusion in the Treatment of Lumbar Stenosis on the Degree of Post-operative Functional Incapacity (BDYNCLIN)
Status: RECRUITING
Conditions: Degenerative Lumbar Spinal Stenosis
Interventions: DEVICE: B-DYN|DEVICE: Conventional Bolted fusion (with or without cage)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Serious Gaming for Chemotherapy-induced Nausea and Vomiting
Status: RECRUITING
Conditions: Neoplasms|Chemotherapy-induced Nausea and Vomiting
Interventions: BEHAVIORAL: eSSET-CINV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer
Status: COMPLETED
Conditions: Human Papillomavirus Infection|Stage I Oral Cavity Squamous Cell Carcinoma|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Oral Cavity Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Oral Cavity Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Oral Cavity Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma|Stage IVC Oropharyngeal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Effects on Lipoproteins and Thrombogenic Activity
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Coronary Heart Disease Risk Reduction|Heart Diseases|Hyperlipoproteinemia|Myocardial Ischemia|Thrombosis
Interventions: BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department
Status: COMPLETED
Conditions: Heart Failure, Congestive|Cardiomyopathy
Interventions: DRUG: recombinant B-type, natriuretic peptide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: COVID19 ARDS
Interventions: BIOLOGICAL: Ex vivo expanded Wharton's Jelly Mesenchymal Stem Cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Japanese Treat and Extend Study of Aflibercept in Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Efavirenz|DRUG: Rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mirror Therapy Combined With Task- vs. Impairment-oriented Rehabilitation Program
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Stroke|Cerebrovascular Disorders
Interventions: BEHAVIORAL: Mirror therapy|BEHAVIORAL: Task-oriented approach|BEHAVIORAL: Impairment-oriented approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)
Status: COMPLETED
Conditions: Neurofibromatosis 1 and 2 (NF1 and NF2)
Interventions: BEHAVIORAL: hand-held dynamometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer Patients
Interventions: DRUG: Dexmedetomidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Depodur Efficacy in Decreasing Post Operative Pain After Off Pump Coronary Artery Bypass Grafting (OP-CABG)
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Depodur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intranasal Dexmedetomidine Sedation During Intra-articular Joint Injections in Pediatric Population
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis|Joint Inflammation
Interventions: DRUG: Dexmedetomidine|DRUG: Sedatives/Hypnotics,Other
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Low Starch Diet in Patients With Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Spondyloarthritis|Ankylosing Spondylitis
Interventions: BEHAVIORAL: Low Starch Diet (LSD)|BEHAVIORAL: General healthy eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1
Status: COMPLETED
Conditions: AIDS Dementia Complex|HIV Infections
Interventions: DRUG: Nimodipine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Mablet (Magnesium-supplement)|DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Head of Bed Elevation in Symptoms of Patients With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: OTHER: Head of bed elevation|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Standardization of Secale Cereale Allergen Extract
Status: COMPLETED
Conditions: Allergy to Grass Pollen (Secale Cereale)
Interventions: BIOLOGICAL: Four different concentrations of Secale cereale allergen extract, positive control and negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation
Status: COMPLETED
Conditions: Therapeutic Plasma Exchange|Anticoagulant Therapy
Interventions: DEVICE: Active Comparator: centrifuge TPE with citrate|DEVICE: Active Comparator: Filter TPE with heparin|DRUG: Active comparator: Filter TPE with citrate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A School-based Physical Activity Promotion Intervention in Children. PREVIENE Project
Status: UNKNOWN
Conditions: Motor Activity
Interventions: BEHAVIORAL: Active commuting to/from school|BEHAVIORAL: Active Physical Education lessons|BEHAVIORAL: Active school recess|BEHAVIORAL: Sleep health promotion|BEHAVIORAL: School global intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine
Status: COMPLETED
Conditions: Liver Transplant|Kidney Transplant
Interventions: OTHER: PPM-based Computation Assisted Drug Dosing|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
Status: COMPLETED
Conditions: Intellectual Disability|Exercise|Obesity
Interventions: BEHAVIORAL: Resistance Training for Empowerment (RT-POWER)|BEHAVIORAL: A traditional RT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Adjunctive Therapy With Lacosamide in Adults With Partial-onset Seizures
Status: COMPLETED
Conditions: Epilepsy|Partial-onset Seizures
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Sitavig (Acyclovir) Buccal Tablet With a Placebo in the Treatment of Herpes Labialis in Participants Whose Immune System Works Normally
Status: COMPLETED
Conditions: Recurrent Herpes Labialis
Interventions: DRUG: Acyclovir 50mg buccal/topical tablet, BAYM008894/UI1614773|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Culotte Technique Versus TAP Stunting for the Treatment of de Novo Coronary Bifurcation Lesion With Drug-eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease|Restenosis
Interventions: PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Lung Metastases
Interventions: RADIATION: SBRT dose escalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ARC1779 in Patients With Acute Myocardial Infarction Undergoing PCI
Status: TERMINATED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK, PD and Safety of Tegoprazan 12.5 mg After Oral Administration in Healthy Subjects
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DRUG: Tegoprazan 12.5mg|DRUG: Tegoprazan 25mg|DRUG: Famotidine 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Circuit Training Combining Different Types of Distal Robot-assisted and Task-oriented Therapy on Motor Control, Motor and Daily Functions, and Quality of Life After Stroke
Status: RECRUITING
Conditions: Stroke Patients
Interventions: DEVICE: Robots can aid in distal UE rehabilitation through exoskeleton (EXO)|DEVICE: End-effector robot-assisted therapy (EE)|BEHAVIORAL: Unilateral task-oriented therapy|BEHAVIORAL: Bilateral task-oriented therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Treatment of Chronic Instability of the Lateral Ankle Joint by Repairing the Anterior Talofibular Ligament Under Total Arthroscopy
Status: UNKNOWN
Conditions: Anterior Talofibular Ligament Injury|Ankle Sprains
Interventions: PROCEDURE: Arthroscopy surgery|PROCEDURE: BrostrÖm surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for Elderly Patients Diagnosed With Localized HER2 Positive Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|HER-2 Positive Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Weekly Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of a New Oral Extended-Release Formulation Containing Parnaparin Sodium, Administered Add-on Therapy
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Combined Training Program for Veterans With Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Amnestic Mild Cognitive Impairment
Interventions: BEHAVIORAL: Combined Aerobic and Resistance Exercise|BEHAVIORAL: Stretching Exercises|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Factors in the Treatment of the Multiple Gingival Recessions
Status: COMPLETED
Conditions: Growth Factors, Combined Defect of|Gingival Recession
Interventions: PROCEDURE: CAF only|PROCEDURE: CAF+CGF|PROCEDURE: CAF+A-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Breast Cancer Female|Breast Cancer Stage I|Breast Cancer Stage II|Breast Cancer Stage III|Mild Depression|Moderate Depression
Interventions: OTHER: MBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Individual, Dyadic, and Collaborative Plans on Physical Activity in Parent-Child Dyads
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Individual Planning|BEHAVIORAL: Dyadic Planning|BEHAVIORAL: Collaborative Planning|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: 30000 IU Per Week Vitamin D Treatment in PCOS Patients
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia
Status: COMPLETED
Conditions: Hyperalgesia|Opioid-Related Disorders
Interventions: DRUG: Acetazolamide|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clopidogrel to Prasugrel in Acute Coronary Syndrome (ACS) Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study Comparing Topical Diclofenac/Menthol Gels With Voltaren Gel and Oral Diclofenac Sodium
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac sodium|DRUG: Menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Detection of Silent Myocardial Ischemia
Status: ENROLLING_BY_INVITATION
Conditions: Ischemic Heart Disease|Silent Myocardial Ischemia|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: CMR stress perfusion imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleep and Creativity
Status: WITHDRAWN
Conditions: Creativity Performance in Healthy Subjects
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS) over the left inferior frontal gyrus (IFG)|DEVICE: Transcranial Magnetic Stimulation (TMS) over the left inferior parietal lobule (IPL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Self-Management for Amputee Rehabilitation Using Technology
Status: COMPLETED
Conditions: Unilateral Trans Tibial/Femoral Lower Limb Amputation
Interventions: DEVICE: Self-Management for Amputee Rehabilitation using Technology [SMART]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Status: RECRUITING
Conditions: Sickle Cell Anemia|Beta-thalassemia Major|Diamond-blackfan Anemia
Interventions: BIOLOGICAL: CD3/CD19 depleted leukocytes|BIOLOGICAL: CD45RA depleted leukocytes|DRUG: Hydroxyurea|DRUG: Rituximab|DRUG: Alemtuzumab|DRUG: Fludarabine|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Passive Cooling Versus Blanket-Roll III on The Myocardial Function of Asphyxiated Neonates
Status: COMPLETED
Conditions: Hypoxic Encephalopathy|Birth Asphyxia|Neonatal Encephalopathy|Hypothermia, Newborn
Interventions: DEVICE: Passive cooling application|DEVICE: cooling using Blanket roll III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Immunoglobulins for the Treatment of Primary Sjögren's Syndrome Associated Painful Sensory Neuropathies
Status: RECRUITING
Conditions: Primary Sjögren's Syndrome Painful Sensory Neuropathies
Interventions: DRUG: Privigen® 100mg/ml at the dose of 2g/kg of body weight|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension
Status: COMPLETED
Conditions: Pregnancy Induced Hypertension
Interventions: DRUG: Bupivacaine-fentanyl|DRUG: Bupivacaine-fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biosimilar Erythropoietin in Anaemia Treatment (Maintenance Phase Study)
Status: COMPLETED
Conditions: Renal Anemia
Interventions: DRUG: EPREX®|DRUG: EPIAO®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Assessing Several Schedules of Oral S-1 in Combination With a Fixed Dose of Oxaliplatin and Irinotecan
Status: COMPLETED
Conditions: Digestive Cancer
Interventions: DRUG: S-1|DRUG: Irinotecan|DRUG: Oxaliplatin|OTHER: G-csf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum and Tissue Level of Interleukin-15 (IL-15) and IL-15 Receptor Alpha (IL-15Rα) in Mycosis Fungoides
Status: RECRUITING
Conditions: Mycosis Fungoides
Interventions: RADIATION: ultraviolet phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Cellular Immunotherapy in Patients With Metastatic Bladder Urothelial Carcinoma
Status: TERMINATED
Conditions: Urinary Bladder Neoplasm
Interventions: BIOLOGICAL: autologous Tcm cells immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ACU-D1 in the Treatment of Acne Rosacea
Status: COMPLETED
Conditions: Acne Rosacea
Interventions: DRUG: ACCU-D1|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Intraoperative Accuracy of 3D-planned and Guided Osteotomies of the Hand and Forearm
Status: COMPLETED
Conditions: Posttraumatic or Congenital Bone Deformity
Interventions: DEVICE: EUDAMED CIV-14-03-011940
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Ablation Therapy With Bipolar Radio Frequency for Nonresectable Bile Duct Cancer
Status: COMPLETED
Conditions: Nonresectable Bile Duct Cancer
Interventions: DEVICE: Ablation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test Whether Itraconazole Influences the Amount of BI 1584862 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1584862|DRUG: itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Desloratadine and pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
Status: RECRUITING
Conditions: Amputation|Amputation; Traumatic, Leg, Lower|Limb; Absence, Congenital, Lower|Prosthesis User|Lower Limb Amputation Above Knee (Injury)|Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions: DEVICE: Ossur Power Knee|DEVICE: Reboocon Intuy Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CEND-1 in Combination With Neoadjuvant FOLFIRINOX With or Without Panitumumab
Status: RECRUITING
Conditions: Colon Cancer|Pancreas Cancer|Digestive Cancer
Interventions: DRUG: CEND-1|DRUG: Panitumumab|DRUG: Folfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Squamous NSCLC Patients With Anlotinib Combined With Pemetrexed and Cisplatin
Status: UNKNOWN
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib|DRUG: pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Use of Telepsychiatry for Outpatients
Status: COMPLETED
Conditions: Borderline Personality Disorder|Depressive Disorder|Ptsd|Anxiety Disorders
Interventions: OTHER: Case management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safer Sex Intervention for Male Clients of Female Sex Workers in Tijuana, Mexico
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Hombre Seguro|BEHAVIORAL: Didactic attention-control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcranial Photobiomodulation for the Treatment of Opioid Cravings
Status: COMPLETED
Conditions: Opioid-use Disorder|Depression, Anxiety|Craving
Interventions: DEVICE: unilateral transcranial photobiomodulation, near infrared mode|DEVICE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-case Design to Investigate a Compensatory Strategy Game Supporting Goal Management Training
Status: RECRUITING
Conditions: Acquired Brain Injury|Executive Dysfunction|Goal Management Training|Compensatory Strategy Training|Serious Gaming
Interventions: BEHAVIORAL: Intervention during phase B: Compensatory brain game supporting Goal Management Training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cobalamin Status in Young Children With Developmental Delay
Status: COMPLETED
Conditions: Vitamin B 12 Deficiency
Interventions: DIETARY_SUPPLEMENT: Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teneligliptin(MP-513) Versus Placebo in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MP-513|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Erector Spinea Plane Block Compared to Peritoneal Block in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: Peritoneal block|PROCEDURE: Ultrasound guided erector spinae plane block|OTHER: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DEVICE: LIPOSORBER® LA-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: PROCEDURE: Early Mobilization Protocol|PROCEDURE: Late Mobilization Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-Host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) Patients
Status: TERMINATED
Conditions: Graft vs Host Disease
Interventions: DRUG: ASEDs|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influenza A 2009 H1N1 Challenge Study in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Ca/04/2009/H1N1 Vero Grown Challenge Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: Very Low Nicotine Content Cigarettes|OTHER: Intermediate Nicotine Content Cigarettes|OTHER: Normal Nicotine Content Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apatinib Versus Placebo as a Third Line Treatment in Patients With Advanced or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Carcinoma
Interventions: DRUG: apatinib tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Disposable Flexible Bronchoscope, aScope IV
Status: TERMINATED
Conditions: Respiratory Insufficiency|Pneumonia|Atelectasis
Interventions: DEVICE: Bronchoscope reusable (Storz 8402 2x)|DEVICE: Bronchoscope disposable (aScope 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chest Physiotherapy in Infants Between 0 and 12 Months Old With Acute Bronchiolitis SRV(+)
Status: COMPLETED
Conditions: Bronchiolitis, Viral
Interventions: OTHER: Prolonged slow expiration+provoked coughing|OTHER: Manual chest wall vibration|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Dulaglutide on the Action of Warfarin in Healthy Participants
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: dulaglutide|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Azimilide Dihydrochloride on Renal Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Azimilide dihydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: ARC1905
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
Status: SUSPENDED
Conditions: Medulloblastoma
Interventions: DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Lomustine|DRUG: Mesna|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Sodium Thiosulfate|OTHER: Survey Administration|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HDL Lipidomic, Proteomic and Functional Changes in Women After Eating Eggs
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: OTHER: Whole egg|OTHER: Yolk-free egg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tirelizumab in Combination With Carboplatin and Albumin-binding Paclitaxel for Neoadjuvant Therapy in HNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Oral Cancer
Interventions: DRUG: Tirelizumab ,+Carboplatin+albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
Status: RECRUITING
Conditions: Gender Dysphoria
Interventions: OTHER: Ultrasound guided Continuous Infraclavicular Brachial Plexus Block|OTHER: Ultrasound guided Continuous Femoral Nerve Block|OTHER: Ultrasound guided Pudendal Nerve Block|DRUG: Bupivacaine|OTHER: Bilateral ultrasound guided Transversus Abdominis Plane Block|OTHER: Bilateral spermatic cord block|OTHER: Pecs I & II Block|OTHER: Local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risky Drinkers and the Web: a RCT Study in Region Friuli-Venezia Giulia.
Status: COMPLETED
Conditions: Excessive Drinking
Interventions: BEHAVIORAL: Web assisted brief motivational interview on risky drinking|BEHAVIORAL: Face to Face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexmedetomidine Wound Infiltration in Cesarean Section
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Dexmedetomidine|DRUG: Ropivacaine|DRUG: Dexmedetomidine - Ropivacaine|OTHER: 0,9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Irbesartan, Ciprofibrate and Their Combination Onto the Endothelial Functions
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: Irbesartan|DRUG: Ciprofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Prolonged Exposure in the Military
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Extended Training in Prolonged Exposure Therapy for PTSD|BEHAVIORAL: Standard Training in Prolonged Exposure Therapy for PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Farabloc Fabric With Placebo on Alleviation Hot Flash in Menopausal Women
Status: UNKNOWN
Conditions: Menopause
Interventions: DEVICE: Farabloc|DEVICE: Nylon Fabric
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: dCBTi With and Without Coaching Support
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: dCBTi|BEHAVIORAL: Virtual coaching|BEHAVIORAL: Non-therapist coaching|BEHAVIORAL: Therapist coaching|BEHAVIORAL: Sleep Hygiene and Self-Monitoring Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autism Research Project With Non-Invasive Near-Infrared Light Stimulation
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Transcranial infrared light stimulation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modification for Weight Reduction With Peer Support Among Adults in an Urban Slum of Karachi, Pakistan
Status: COMPLETED
Conditions: Weight Loss
Interventions: BEHAVIORAL: Peer-supported, WhatsApp-assisted lifestyle modification intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Cervical Cancer Prevention Program Kenya: Overcoming Obstacles to Care, Promoting Understanding of HPV Natural History
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer Prevention|Cervical Cancer
Interventions: OTHER: Self-collection of vaginal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early Glaucoma
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Epigallocatechin-gallate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Dose of Combination of Rocuronium and Cisatracurium
Status: COMPLETED
Conditions: Chronic Otitis Media|Anesthesia
Interventions: DRUG: 10% reduction of combination of Esmeron® and Nimbex®|DRUG: 20% reduction of combination of Esmeron® and Nimbex®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of an Absorbent Foam Dressing Containing Silver (Mepilex Ag) Versus the Same Dressing Without Silver Used on Subjects With Venous Leg Ulcers or Mixed Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcers|Mixed Leg Ulcers
Interventions: DEVICE: Mepilex Ag|DEVICE: Mepilex without Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Subcutaneous Secukinumab (AIN457) for Moderate to Severe Chronic Plaque-type Psoriasis Assessing Different Doses and Dose Regimens
Status: COMPLETED
Conditions: Moderate to Severe Plaque-type Psoriasis
Interventions: DRUG: AIN457 150mg|DRUG: AIN457 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
Status: TERMINATED
Conditions: Neuropathy|Pain|Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: DRUG: Calcium Gluconate|DRUG: Magnesium Sulfate|OTHER: Placebo|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tllsh2910 for Ataxia and Gut Microbiota Alteration in Patients of Multiple System Atrophy
Status: TERMINATED
Conditions: Ataxia, Cerebellar|Multiple System Atrophy
Interventions: DRUG: Tllsh2910|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: AlloStim®|PROCEDURE: cryoablation|OTHER: Physician's Choice (PC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Versus Pemetrexed as Second-Line Therapy in Treating Patients With Advanced Lung Adenocarcinoma
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum
Status: RECRUITING
Conditions: Hepatitis C
Interventions: OTHER: Patient-Centered Electronic App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Post-Operative Analgesic Effects of PCAM With Dexmedetomidine 1 mcg/ml vs PCAM With Dexmedetomidine 2 mcg/ml
Status: COMPLETED
Conditions: Post-Operative Analgesia|Opioid Use, Unspecified|Laparotomy Surgery
Interventions: DRUG: Dexmedetomidine 1 mcg/ml|DRUG: Dexmedetomidine 2 mcg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety Evaluation of Embella (Deoxycholic Acid, by Espad Pharmed Co.) in Management of Submental Fat
Status: COMPLETED
Conditions: Submental Fullness
Interventions: DEVICE: Embella (Deoxycholic acid, produced by Espad Pharmed Co.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximizing Outcome of Multiple Sclerosis Transplantation
Status: TERMINATED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: rATG|DRUG: Methylprednisolone|DRUG: G-CSF|BIOLOGICAL: IVIg|BIOLOGICAL: Autologous Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Asthma Exacerbation Rate in Children by Non-invasive Monitoring of Inflammatory Markers in Exhaled Breath (Condensate): the RASTER Study
Status: COMPLETED
Conditions: Asthma|Children|Home Monitoring|Exhaled Breath Condensate|Non-invasive Inflammatory Markers|Volatile Organic Compounds
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p