pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Benefit of a Hospital Intervention in Patients With Hepatic Steatosis
Status: NOT_YET_RECRUITING
Conditions: Hepatic Steatosis
Interventions: OTHER: Specialized Unit|OTHER: Usual Follow-Up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Insulet Artificial Pancreas Evaluating Meal Performance and Moderate Exercise (IDE2)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Insulet AP (artificial pancreas) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Prospective Observational Study on Incidence of Invasive Fungal Infections Among Patients With Acute Lymphoblastic Leukemia Ph-negative
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Adult|Invasive Fungal Infections
Interventions: OTHER: observation of invasive fungal infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: RADIATION: DCE-MRI, DW-MRI and MRS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Peripherally Inserted Central Catheters to Long Peripheral Catheters in Pediatrics
Status: COMPLETED
Conditions: Vascular Access Device Complications
Interventions: DEVICE: Long Peripheral Catheter|DEVICE: Peripherally Inserted Central Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Relationship Between CMV* Reactivation and Anti-cytokine Treatment in Critical COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19, Cytomegalovirus (CMV), Tocilizumab, Anakinra, Mortality
Interventions: DIAGNOSTIC_TEST: CMV DNA analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of an Internet-based Guided Self-help and a Group Therapy for Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: BEHAVIORAL: Internet-based guided self-help for tinnitus|BEHAVIORAL: Cognitive-behavior group therapy for tinnitus|OTHER: Internet discussion forum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Short Stature
Interventions: DIAGNOSTIC_TEST: Evaluation of the prevalence of truly (authentified) idiopathic short stature after multidisciplinary clinico-radiological evaluation|PROCEDURE: analysis in a multidisciplinary consultation meeting via a secure platform (ShareConfrère) for evaluation by multidisciplinary team|GENETIC: Whole genome analysis for authentified idiopathic short stature
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of Camrelizumab Combined With Microwave Ablation and Chemotherapy in the Treatment of Colorectal Cancer Liver Metastasis/Pulmonary Metastasis
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer Metastatic|Liver Metastases|Lung Metastases
Interventions: DRUG: Camrelizumab|PROCEDURE: ablation|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab and Ipilimumab Combined With Chemotherapy Compared to Chemotherapy Alone in First Line NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TXA in Spinal Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease
Interventions: DRUG: Tranexamic Acid|DRUG: Saline Solution|DIAGNOSTIC_TEST: Visual Acuity Exam|DIAGNOSTIC_TEST: 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Apollo System for Children With ADHD
Status: UNKNOWN
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DEVICE: 8 weeks of home based use.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Efficacy and Safety of FK506 Combined With Mycophenolate Mofetil (MMF) in Lupus Nephritis (III/IV/V)
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Multitherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)
Status: UNKNOWN
Conditions: Polycystic Ovarian Syndrome|Subfertility|ICSI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Listening Benefits From a Hearing-aid App, a Personal Sound Amplification Product, and a Hearing Aid in Hearing-impaired Listeners
Status: RECRUITING
Conditions: Hearing Disorders
Interventions: DEVICE: personal sound amplification product, hearing aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognition at Altitude in HEMS - Part II
Status: COMPLETED
Conditions: Hypobaric Hypoxia|Hypobaric Normoxia|Cognitive Performance|Emergency Medicine|Stress Physiology
Interventions: OTHER: Altitude exposure in hypobaric normoxic condition|OTHER: Altitude exposure in hypobaric hypoxic condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cervical Arthroplasty "Fixed Core" Versus "Movable Core": Clinical and Radiological Impact in the Medium Term
Status: TERMINATED
Conditions: Neck Pain|Back Pain
Interventions: DEVICE: Mobi-C prothesis|DEVICE: ProDisc-C prothesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawi
Status: COMPLETED
Conditions: Malaria, Falciparum|HIV Infections
Interventions: DRUG: Monthly sulfadoxine/pyrimethamine|DRUG: 2-dose sulfadoxine/pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Cardiotoxicity Monitoring With Single-lead Electrocardiogram
Status: COMPLETED
Conditions: Cardiotoxicity
Interventions: DEVICE: Remote 1-minute single-lead electrocardiogram (ECG) monitoring in cancer patients after the first polychemotherapy cycle.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
Status: UNKNOWN
Conditions: Cardiovascular Risk Factor|Cardiovascular Diseases|Diabetes|Physical Activity|Sedentary Lifestyle
Interventions: OTHER: Breaking up sitting with walking breaks|OTHER: Prolonged sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Telbivudine in Blacks/African Americans and Hispanics/Latinos With Compensated Chronic Hepatitis B During 52 Weeks
Status: WITHDRAWN
Conditions: Compensated Chronic Hepatitis B
Interventions: DRUG: Telbivudine/LDT600A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmation of the Antiviral Effects of Midodrine Identified With a Gene Expression Signature-based Screening of Inluenza A Virus Infected Cells
Status: COMPLETED
Conditions: Influenza A Virus Infection
Interventions: DRUG: Gutron® treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Effect of SKY on Psychosocial Parameters of Type 2 Diabetic Patients After a 6 Days
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: OTHER: SKY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|OTHER: Placebo matching Ipilimumab|OTHER: Placebo matching Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting the Optimal Mean Arterial Pressure in Hypoxic Ischemic Brain Injury After Cardiac Arrest
Status: WITHDRAWN
Conditions: Cardiac Arrest
Interventions: OTHER: Individualized perfusion targets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of ellaOne® (Ulipristal Acetate) for Emergency Contraception in Postmenarcheal Adolescent Girls and Women
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: ellaOne® (ulipristal acetate)|DRUG: ellaOne® (ulipristal acetate)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using the Blood Eosinophil Count to Guide Systemic Corticosteroid Treatment in Asthma Exacerbations
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma Attack|Asthma
Interventions: OTHER: Standard care|OTHER: Eosinophil-directed care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol-based Management and Perioperative Outcomes in Patients With Chronic Antithrombotic Therapy
Status: UNKNOWN
Conditions: Antithrombotic Therapy|Perioperative Care|Perioperative Outcomes
Interventions: DRUG: Protocol-based management of perioperative antithrombotic therapy|DRUG: Routine management of perioperative antithrombotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identifying Genetic Markers That Predict Response to Paclitaxel in Patients With Newly Diagnosed Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: GENETIC: Microarray analysis|OTHER: Laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Whole-body Vibration Training on the Heart Rate Variability Cardiac in Kidney Transplantation
Status: UNKNOWN
Conditions: Renal Transplant Recipients
Interventions: OTHER: whole-body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|Atypical Chronic Myeloid Leukemia|Chronic Monocytic Leukemia|Myelofibrosis|Myelodysplastic/Myeloproliferative Neoplasm
Interventions: DRUG: Hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the Efficacy and Safety of Chidamide in Combination With Camrelizumab and Carboplatin or Capecitabine in the Second and Third Line Treatment of Relapsed/Metastatic Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: chidamide|DRUG: camrelizumab|DRUG: carboplatin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis
Status: UNKNOWN
Conditions: Suspected Early Lyme Neuroborreliosis
Interventions: DRUG: doxycycline|DRUG: ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Hs-CRP in Periodontitis Patients With or Without Diabetes
Status: COMPLETED
Conditions: Periodontal Disease|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: Scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of N-Acetylcysteine (NAC) on Creatinine in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Long-Term Intermittent Administration of Levosimendan in Patients With Advanced Heart Failure
Status: UNKNOWN
Conditions: Advanced Heart Failure
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Netrin 1 and Its Receptor Unc5b as Markers of Periodontal Disease
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: non surgical periodontal treatment|OTHER: Gingival crevicular fluid, saliva and serum collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Citrate Dialysate in Online Hemodialfiltration
Status: COMPLETED
Conditions: Hemodiafiltration|Heparin|Haemodialysis|Citrate Reaction
Interventions: PROCEDURE: Pre-dilution online hemodiafiltration with citrate dialysate|PROCEDURE: Post-dilution hemodiafiltration with citrate dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of ABH001 in the Treatment of Patients With Epidermolysis Bullosa Who Have Wounds That Are Not Healing
Status: TERMINATED
Conditions: Epidermolysis Bullosa
Interventions: BIOLOGICAL: ABH001|OTHER: Control wound treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Cognitive Enhancement
Status: COMPLETED
Conditions: Fluid Inteligence|Modafinil|Healthy Young Subjects|Resting State Networks
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm (AAA)|Thoracic Aortic Aneurysm (TAA)|Carotid Stenosis|Visceral Artery Aneurysm
Interventions: OTHER: Endovascular Aortic Repair (EVAR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus
Status: RECRUITING
Conditions: Vulvar Lichen Sclerosus
Interventions: DEVICE: Fractionated CO2-laser|DRUG: Clobetasol Propionate 0.05% Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topography Guided LASIK by Different Protocols for Treatment of Astigmatism
Status: COMPLETED
Conditions: Refractive Surgery
Interventions: PROCEDURE: topography guided ablation|PROCEDURE: manifest refraction|PROCEDURE: full topography modified refraction|PROCEDURE: partial topography modified refraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Pregnenolone in Veterans With Mild TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additional Effects of Sternocleidomastoid Release With SNAGS in the Management of Cervicogenic Headache
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervicogenic Headache
Interventions: PROCEDURE: Electrotherapy and physical agents|PROCEDURE: Headache SNAGs|PROCEDURE: Sternocleidomastoid Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Intravenous ketamine0.5mg/kg|DRUG: Nebulized Ketamine 1mg/kg|DRUG: Nebulized Ketamine 2mg/kg|DRUG: saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Rabeprazole From Idiazole 20mg DR Tabs (GSK, Egypt) and PARIET 20 mg DR Tabs (JANSSEN, EGYPT)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Idiazole 20mg DR tabs|DRUG: PARIET 20 mg DR tabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation
Status: WITHDRAWN
Conditions: Lung Transplant
Interventions: DRUG: thymoglobulin (intraoperative)|DRUG: thymoglobulin (postoperative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of GS-0189 (Formerly FSI-189) as Monotherapy and in Combination With Rituximab in Participants With Relapsed/Refractory Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Non-hodgkin Lymphoma
Interventions: DRUG: GS-0189|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Family Sodium Watcher Program on Outcomes in Heart Failure Patient-Family Caregiver Dyads
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Family SWaP intervention|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ib/IIa Trial to Evaluate Oregovomab and Nivolumab in Epithelial Cancer of Ovarian, Tubal or Peritoneal Origin
Status: TERMINATED
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Nivolumab|DRUG: Oregovomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Symptoms|Mild Traumatic Brain Injury
Interventions: DEVICE: CNRM DTx|OTHER: Psychoeducation Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Escalating, Constant and Reduction Energy Output in SWL for Renal Stones
Status: COMPLETED
Conditions: Renal Stones
Interventions: RADIATION: Escalating Energy SWL|RADIATION: Constant Energy SWL|RADIATION: Reduction Energy SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin|DRUG: Empagliflozin|DRUG: Dapagliflozin|DRUG: Dipeptidyl Peptidase-4 Inhibitor (DPP-4)|DRUG: Glucagon-Like Peptide-1 Agonist (GLP-1)|DRUG: Thiazolidinedione (TZD)|DRUG: Sulfonylureas|DRUG: Insulin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of ICU-Related Anxiety in Lung Transplantation by Virtual Reality Therapy - PIRAT Study
Status: UNKNOWN
Conditions: Transplantation, Lung|Depression, Anxiety|PTSD
Interventions: BEHAVIORAL: Exposure therapy with Virtual Reality.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Systematic Investigation of Blacks With Stroke - GENOMICS
Status: RECRUITING
Conditions: Hypertension|Adult|Dyslipidemias|Physical Inactivity|Diabetes|Alcohol Consumption
Interventions: DEVICE: Riskometer Application|BEHAVIORAL: Routine Clinic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bacillus Clausii in Liver Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Transplantation Infection|Liver Grafting|Hepatic Transplantation
Interventions: DIETARY_SUPPLEMENT: Bacillus clausii Probiotic liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Chemoimmunotherapy for High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma (NB)
Interventions: DRUG: Irinotecan|DRUG: temozolomide|BIOLOGICAL: Hu3F8|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile-App Training to Reduce Body Image Disorder Symptoms and Associated Features in Female University Students
Status: COMPLETED
Conditions: Body Image Disorder|Body Dysmorphic Disorders|Eating Disorders
Interventions: DEVICE: GGBI: Positive Body Image (Mobile App)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Scalable Psychological Intervention for Earthquake Survivors in Türkiye
Status: RECRUITING
Conditions: Psychological Distress|Impaired Social Functioning|Depressive Symptoms
Interventions: BEHAVIORAL: Problem Management Plus (PM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumour Cells in Somatuline Autogel Treated NeuroEndocrine Tumours Patients
Status: COMPLETED
Conditions: NeuroEndocrine Tumours
Interventions: DRUG: lanreotide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Minocycline in Opioid-maintained Patients
Status: COMPLETED
Conditions: Opioid Dependence|Pain
Interventions: DRUG: Minocycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Proxalutamide (GT0918) Treatment for Outpatients With Mild or Moderate COVID-19 Illness
Status: COMPLETED
Conditions: Efficacy and Safety
Interventions: DRUG: Proxalutamide (GT0918)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation (NMES) in Stroke-diagnosed Individuals
Status: UNKNOWN
Conditions: Hemiplegia
Interventions: DEVICE: NeuromuscularElectricalStimulation+ConventionalPhysiotherapy|OTHER: Conventional physiotherapy and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Towards a Tailored Approach for Patients With Acute Diverticulitis and Abscess Formation. A Multicenter Cohort Analysis
Status: RECRUITING
Conditions: Acute Diverticulitis|Diverticular Diseases|Diverticulitis of Sigmoid|Acute Diverticular Perforation|Diverticulitis, Colonic|Sepsis
Interventions: PROCEDURE: Conservative treatment with antibiotics and eventual percutaneous image-guided drainage of the abscess
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enoxaparin Versus Aspirin in Patients With Cancer and Stroke
Status: COMPLETED
Conditions: Cancer Patients First-ever Acute Ischemic Stroke
Interventions: DRUG: Enoxaparin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation in the Home Setting for Older Adults In the Early Period After Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction (AMI)
Interventions: BEHAVIORAL: Home-based physical therapy|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Analgesic Efficacy of Protocol for Primary Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Knee Arthroplasty, Total
Interventions: DRUG: ultrasound guided injection of local anesthetic between the popliteal artery and the capsule of the knee (iPACK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Interventions for Gamblers With and Without Co-occurring Problem Drinking
Status: COMPLETED
Conditions: Gambling|Alcohol Consumption
Interventions: BEHAVIORAL: Gambling Internet Intervention|BEHAVIORAL: Check Your Drinking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
Status: ACTIVE_NOT_RECRUITING
Conditions: Dyskeratosis Congenita|Hoyeraal Hreidarsson Syndrome|Revesz Syndrome|Aplastic Anemia
Interventions: BIOLOGICAL: alemtuzumab|DRUG: Fludarabine|DRUG: Cyclosporins|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Interictal Dysfunction in Epilepsy
Status: WITHDRAWN
Conditions: Epilepsy
Interventions: DEVICE: transcranial direct current stimulation|OTHER: Cognitive Remediation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Web, Group, and Telehealth Formats of a Military Parenting Program
Status: COMPLETED
Conditions: Parenting
Interventions: OTHER: ADAPT Self Directed web|OTHER: ADAPT individualized web-facilitated|OTHER: Group-based ADAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Pain|Stomatitis
Interventions: DRUG: Gabapentin|DRUG: Methadone Hydrochloride|DRUG: Oxycodone Hydrochloride|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CpG 7909/Montanide ISA 720 With or Without Cyclophosphamide in Combination Either With NY-ESO-1-derived Peptides or the NY-ESO-1 Protein for NY-ESO-1-expressing Tumors
Status: COMPLETED
Conditions: NY-ESO-1-expressing Tumors
Interventions: BIOLOGICAL: Vaccine only|BIOLOGICAL: Vaccine + cyclophosphamide|BIOLOGICAL: Vaccine only|BIOLOGICAL: Vaccine + cyclophosphamide|BIOLOGICAL: Vaccine only|BIOLOGICAL: Vaccine + cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Diversity and Composition of the Microbiota in the Development of Pediatric Fatty Liver
Status: UNKNOWN
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity|Metabolic Syndrome
Interventions: OTHER: Multidisciplinary intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis
Status: TERMINATED
Conditions: Asthma, Allergic|Rhinitis,Allergic|Allergy
Interventions: DRUG: Azelastine-Fluticasone Nasal|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of speCtraL Computed tomogrAphy to impRove specIficity of Cardiac compuTed tomographY
Status: UNKNOWN
Conditions: Coronary Stenosis|Myocardial Ischemia|Cardiovascular Diseases
Interventions: DEVICE: Dual-layer spectral detector CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extended Access Program of Vedolizumab IV in Ulcerative Colitis and Crohn's Disease
Status: TERMINATED
Conditions: Colitis, Ulcerative|Crohn Disease
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of an Exercise Programme on Neuromuscular Outcomes in Gaelic Sport
Status: COMPLETED
Conditions: Focus of Study is Effects of Neuromuscular Training
Interventions: OTHER: GAA 15|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Exercise to Improve Mitochondrial Dysfunction in Pediatric Obesity
Status: UNKNOWN
Conditions: Pediatric Obesity|Insulin Resistance|Mitochondrial Dysfunction
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEC-C and Thioguanine for R/R AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Thioguanine (Tabloid ®)|DRUG: DecitabineCedazuridine (Inqovi ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pharmacist Post-discharge Phone Calls on Hospital Readmission and Patient Medication Literacy and Adherence
Status: TERMINATED
Conditions: Medication Adherence & Literacy to Predict Readmission|Post-discharge Pharmacist Counseling to Prevent Readmissions
Interventions: OTHER: Post-discharge counseling on medication adherence & literacy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis
Status: COMPLETED
Conditions: Vaginosis, Bacterial|Vaginal Infection
Interventions: DRUG: GW05|DRUG: GW05|DRUG: GW05|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: HPV E6-specific TCR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance
Status: COMPLETED
Conditions: Sports
Interventions: DIETARY_SUPPLEMENT: Red Spinach Extract (RSE)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Semi-standarized Acupuncture in Chronical Symptomatic Osteoarthritis of the Knee Through: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Acupuncture|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block and Transverse Abdominis Plane Block for Sleeve Gasterectomy
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CT Using MBIR in Crohn's Disease: Prospective Clinical Evaluation of Diagnostic Efficacy, Safety and Patient Outcome.
Status: COMPLETED
Conditions: Radiology|Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Patients who have had split dose CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage
Status: COMPLETED
Conditions: Hypertension|Ventricular Remodeling|Erectile Dysfunctions
Interventions: DRUG: Valsartan 160mg plus HCT 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effects of Bracket's Slot System on the Quantity and Quality of Teeth Movements During Orthodontic Leveling and Alignment Stage
Status: UNKNOWN
Conditions: Moderate and Severe Crowding in Lower Dental Arch
Interventions: DEVICE: Bracket slot 0.018|DEVICE: Bracket slot 0.022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Expandable Cryoballoon on Autonomic Control of the Heart
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: cryoablation of atrial fibrillation using only 28 mm size balloon|DEVICE: cryoablation of atrial fibrillation using expandable balloon (28 / 31 mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Salbutamol 400mcg|DRUG: Budesonide/formoterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Information Prescriptions on Medication Adherence in Emergency Department (ED) Patients
Status: COMPLETED
Conditions: Patient Compliance|Medication Adherence|Medication Non-Adherence
Interventions: BEHAVIORAL: Information prescriptions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Avelumab With Axitinib Versus Sunitinib In Advanced Renal Cell Cancer (JAVELIN Renal 101)
Status: COMPLETED
Conditions: Renal Cell Cancer
Interventions: DRUG: Avelumab (MSB0010718C)|DRUG: Axitinib (AG-013736)|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ProAlgaZyme Novel Algae Infusion: Applications in Immunodeficiency
Status: COMPLETED
Conditions: HIV Infections|Hepatitis B|Dyslipidemia
Interventions: DRUG: ProAlgaZyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patients
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Chloroquine, A-CQ 100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AC-201 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: AC-201, 25mg|DRUG: AC-201, 50mg|DRUG: AC-201, 75mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions for Patients With a Shortened Dental Arch
Status: COMPLETED
Conditions: Anomaly of Dental Arch
Interventions: DEVICE: Removable partial denture (Chrome Cobalt Distal extension)|OTHER: A reduced posterior dental arch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effects of Gabapentin and Paracetamol
Status: COMPLETED
Conditions: Hand Injuries
Interventions: DRUG: Gabapentin 600 mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: ECF|DRUG: IC|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pregnancies After Cryopreservation of Donor Oocytes With an Open or Closed Device
Status: TERMINATED
Conditions: Infertility
Interventions: DEVICE: Cryotop device|DEVICE: CBSvit device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Marginal Bone Height Changes Around Two Different Surface Treated Dental Implants Supporting Mandibular Complete Overdenture.
Status: COMPLETED
Conditions: Assess Marginal Bone Height Changes Around Dental Implants
Interventions: PROCEDURE: Dental Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of 14C-labeled of LXI-15028
Interventions: DRUG: [14C]LXI-15028
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Exercise and Phytoestrogens: Effect on Factors Predisposing to Cardiovascular Disease(CVD) in Postmenopausal Women
Status: COMPLETED
Conditions: Overweight
Interventions: BEHAVIORAL: Placebo + exercise|DIETARY_SUPPLEMENT: Phytoestrogens without exercise|OTHER: Phytoestrogens + exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Culturally Adapted, Social Support-Based, Physical Activity Interventions for South Asian Indian Women in the United States
Status: RECRUITING
Conditions: Sedentary Behavior
Interventions: BEHAVIORAL: Dyad-based Zoom health coaching|BEHAVIORAL: Fitbit activity monitor|OTHER: Electronic newsletters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Lateral Positioning on Bronchial Cuff Pressure of Left-sided Double-lumen Endotracheal Tube During Thoracic Surgery
Status: COMPLETED
Conditions: Lung Cancer|Pneumothorax
Interventions: BEHAVIORAL: Lateral decubitus positioning|DEVICE: Cuff-manometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE Louisiana
Status: COMPLETED
Conditions: Covid19|Vaccine Refusal|Vaccine Hesitancy
Interventions: BEHAVIORAL: COVID-19 Vaccine Education at the Point of COVID-19 Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SomaSignal Tests on Medical Management and Change in Risk in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: SomaSignal Informed Medical Management SSCVD|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain
Status: WITHDRAWN
Conditions: Myofascial Pain Syndrome
Interventions: DRUG: Capsaicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-inflammatory Diet on Inflammatory, Oxidative and Nutritional Markers in Hemodialysis Patients
Status: COMPLETED
Conditions: Inflammation|Malnutrition|Protein Energy Wasting Syndrome|Oxidative Stress|Diet Therapy
Interventions: OTHER: Diet Therapy|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficiency of Esophageal Dilation on Patient With Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Suspected Eosinophilic Esophagitis
Interventions: PROCEDURE: Esophageal dilation|DRUG: Steroid and Proton Pump Inhibitor Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire
Status: COMPLETED
Conditions: Opioid-Related Disorders|Opiate Addiction|Narcotic Abuse|Drug Abuse
Interventions: OTHER: Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Ranging Study to Evaluate the Safety and Tolerability of SCX-001 Cream in Healthy Volunteers With Induced Dermal Incisions
Status: COMPLETED
Conditions: Scarring
Interventions: DRUG: SCX-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy (PDT) Versus Transpupillary Thermotherapy (TTT) in Occult Choroidal Neovascularization (CNV) in Age-related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: PROCEDURE: laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 Questionnaire
Status: RECRUITING
Conditions: Scoliosis; Adolescence|Adolescent|Quality of Life|SRS
Interventions: DEVICE: Brace|PROCEDURE: Surgical correction using implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Blood
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: Gamma Delta Tocotrienols - Low Dose|DRUG: Gamma Delta Tocotrienols - High Dose|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability of Estradiol Valerate and Dienogest 2 mg/2 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Estradiol Valerate and Dienogest 2 mg/ 2 mg Test Drug tablet|DRUG: Estradiol Valerate and Dienogest 2 mg/ 2 mg Reference Product tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Safety of PIM447 in Combination With Ruxolitinib (INC424) and LEE011 in Patients With Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis
Interventions: DRUG: PIM447|DRUG: Ruxolitinib|DRUG: LEE011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH