pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke
Status: COMPLETED
Conditions: Rehabilitation|Recovery of Function|Stroke|Lower Extremity Paresis
Interventions: BEHAVIORAL: Lower extremity Constraint-induced movement therapy(LE-CIMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inhaled Insulin Compared With Subcutaneous Human Insulin Therapy in Adults With Type 1 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Subcutaneous Insulin|DRUG: Inhaled Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas
Status: TERMINATED
Conditions: Sarcoma
Interventions: DRUG: Irinotecan&Temsirolimus:Arm1, Level 1|DRUG: Irinotecan&Temsirolimus:Arm 1, Level 2|DRUG: Irinotecan&Temsirolimus:Arm 2, Level 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
Status: COMPLETED
Conditions: Aggressive Periodontitis
Interventions: DRUG: Klorhex® Gel, rinse and spray|PROCEDURE: Conventional IPT|PROCEDURE: Full-mouth IPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hydration Status When Consuming Alkaline Water Compared to Reverse Osmosis Purified Water.
Status: COMPLETED
Conditions: Hydration
Interventions: DIETARY_SUPPLEMENT: Alkaline water|DIETARY_SUPPLEMENT: Reverse osmosis water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension
Status: UNKNOWN
Conditions: Diabetes|Dyslipidemias|Hypertension
Interventions: DRUG: TRC150094|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of CKD-314
Status: UNKNOWN
Conditions: COVID-19 Pneumonia
Interventions: DRUG: CKD-314+SOC|DRUG: CKD-314 Placebo+SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Enhanced Asthma Management - Uniting Providers for Teens (TEAM-UP for Teens)
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: TEAM-UP for Teens|BEHAVIORAL: Enhanced Care (EC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Primary Delivery of the Anterior Compared With the Posterior Shoulder on Perineal Trauma: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Birth Injuries
Interventions: PROCEDURE: Primary delivery of anterior shoulder|PROCEDURE: Primary delivery posterior shoulder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Power Training in Older Women With Pre-sarcopenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre-sarcopenia|Old Age; Debility
Interventions: PROCEDURE: Power training in women older than 65 years with pre-sarcopenia|PROCEDURE: Multimodal and nonspecific exercises in women older than 65 years with pre-sarcopenia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adjuvant Hormonal Treatment for 24 Months After Radical Prostatectomy in High Risk of Recurrence Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastases
Interventions: DRUG: Leuprorelin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Iron Therapy in Chronic Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate|DIETARY_SUPPLEMENT: Placebo starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of a Nordic Diet Rich in Plant-based Foods and Fish
Status: COMPLETED
Conditions: Prehypertension|Hypertension
Interventions: OTHER: Effects of a Nordic diet rich in plant-based foods and fish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Protein Supplementation in Infants With Brain Injury
Status: COMPLETED
Conditions: Perinatal Stroke|Hypoxic-ischemic Encephalopathy|White Matter Injury
Interventions: DIETARY_SUPPLEMENT: Increased protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy METAZYM for the Treatment Metachromatic Leukodystrophy Treated With Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Metachromatic Leukodystrophy
Interventions: DRUG: rhARSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Unnecessary Use of Heavily Marketed Medications: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Use of Sleep Medications
Interventions: BEHAVIORAL: Computerized alerts|BEHAVIORAL: Alerts Plus Detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study
Status: COMPLETED
Conditions: Cytomegalovirus Infections|HIV Infections|Hypocalcemia
Interventions: DRUG: Magnesium sulfate|DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Role of Bladder Training During Post-operative Hospital Stay After Radical Hysterectomy in Patients
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DEVICE: bladder training|PROCEDURE: No bladder training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care Ultrasound Educational Initiative for Insect Bites
Status: TERMINATED
Conditions: Cellulitis|Insect Bites|Insect Stings
Interventions: BEHAVIORAL: POCUS Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PROSPECTIVE, MULTI-CENTER, OPEN-LABEL, SINGLE-ARM REGISTRATION TRIAL OF THE TUBRIDGE FOR THE TREATMENT OF WIDE-NECKED SMALL AND MEDIUM-SIZED INTRACRANIAL ANEURYSMS
Status: RECRUITING
Conditions: Brain Diseases|Aneurysm|Intracranial Aneurysm|Cardiovascular Diseases
Interventions: DEVICE: Tubridge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABX-EGF in Combination With Paclitaxel and Carboplatin for the Treatment of Advanced Non-Small-Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Neoplasm Metastasis|Lung Cancer
Interventions: DRUG: ABX-EGF|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: BI 770371|DRUG: ezabenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Linagliptin From Prevaglip 5 mg Tablets(Eva Pharma, Egypt) and Trajenta 5 mg Tablets (Boehringer Ingelheim International GmbH, Germany)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Prevaglip (linagliptin)|DRUG: Trajenta (linagliptin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy
Status: COMPLETED
Conditions: Idiopathic Generalized Epilepsy|Partial Onset Seizures|Generalised Tonic-Clonic Seizures
Interventions: DRUG: Perampanel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prehabilitation Intervention to Maximize Early Recovery (PRIMER) in Liver Transplantation
Status: COMPLETED
Conditions: Liver Diseases|End Stage Liver Disease|Frailty
Interventions: DEVICE: Nokia GO Wearable StepTracker|OTHER: Medication Reminder|OTHER: Weekly Check-in appointment with study team or provider
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in the Eradication of Helicobacter Pylori by Different Therapies
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Group1 Vonoprazan Fumarate + amoxicillin + doxycycline|DRUG: Group2 Vonoprazan Fumarate + furazolidone + doxycycline|DRUG: Group3 esomeprazole + colloidal bismuth tartrate + amoxicillin + doxycycline|DRUG: Group4 esomeprazole + colloidal bismuth tartrate + furazolidone + doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate PKs and Efficacy Assessment of Palifermin in Patients With Sarcoma
Status: COMPLETED
Conditions: Sarcoma|Oral Mucositis
Interventions: DRUG: Palifermin|DRUG: Placebo|DRUG: Adriamycin (Doxorubicin)|DRUG: Ifosfamide|DRUG: Vincristine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Interactions Between Fibre and Polyphenols on Colonic Phenolic Acid Production and Biomarkers of Health ( 6 Weeks)
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Tomato, onion and lovage soup (TOL)|OTHER: TOL soup with inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Amiodarone Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Unresectable Lung Non-Small Cell Carcinoma
Interventions: DRUG: Carboplatin|BIOLOGICAL: Durvalumab|DRUG: Paclitaxel|DRUG: Papaverine|RADIATION: Radiation Therapy|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Fish Oil to Reduce ALT Levels in Adolescents
Status: TERMINATED
Conditions: Non-alcoholic Fatty Liver Disease|Fatty Liver
Interventions: DRUG: Omega-3-acid ethyl esters|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cancer|Liver Neoplasms|Metastatic Liver Cancer
Interventions: COMBINATION_PRODUCT: Sorafenib combined with ET140202-T cell|COMBINATION_PRODUCT: TAE combined with ET140202-T cell|BIOLOGICAL: ET140202-T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Status, Morbidity and Mortality in Cemented Versus Press-Fit Hemiarthroplasty
Status: COMPLETED
Conditions: Femoral Neck Fracture
Interventions: DEVICE: Cemented Hip Hemiarthroplasty|DEVICE: VerSys Beaded FullCoat, Zimmer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation
Status: NOT_YET_RECRUITING
Conditions: Metastatic Prostate Carcinoma|Stage III Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: BEHAVIORAL: Patient Navigation|OTHER: Genetic Counseling|OTHER: Survey Administration|OTHER: Best Practice|OTHER: Genetic Counseling|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Study of SHEN26 Capsule in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: SHEN26 capsule|DRUG: SHEN26 capsule|DRUG: SHEN26 placebo|DRUG: SHEN26 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations
Status: UNKNOWN
Conditions: Corneal Epithelial Disruption|Corneal Staining
Interventions: DEVICE: Marketed contact lens care products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study About Nutritional Support of Enhanced Protein in Critical Patients
Status: UNKNOWN
Conditions: Critical Illness
Interventions: DIETARY_SUPPLEMENT: a production consist of various oligopeptides and the whey protein|DIETARY_SUPPLEMENT: basic energy intake|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurocognitive Study for the Aging-a Longitudinal Study With a Greek Cypriot Cohort
Status: RECRUITING
Conditions: Aging|Memory Impairment|Cognitive Decline|Mild Cognitive Disorder
Interventions: BEHAVIORAL: Categorization training|BEHAVIORAL: Psychosocial and Psychoeducational Group training
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging CRF X NOP Interactions in CUD
Status: RECRUITING
Conditions: Cocaine Use Disorder
Interventions: RADIATION: Baseline [C-11]NOP-1A PET Scan|DRUG: Hydrocortisone|RADIATION: Post-hydrocortisone [C-11]NOP-1A PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Effects of ShotBlocker, Virtual Reality Glasses and Cold Application in Subcutaneous Heparin Injection
Status: COMPLETED
Conditions: Subcutaneous Injection
Interventions: DEVICE: Group 1|DEVICE: Group 2|DEVICE: Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Participatory Intervention to Improve Nutrition and Physical Activity in Schoolchildren From Acatlán de Juárez, Jalisco
Status: COMPLETED
Conditions: Sedentary Behavior|Adipose Tissue|Child Obesity
Interventions: BEHAVIORAL: Participatory intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety of Dapoxetine/Tadalafil Combination Therapy
Status: UNKNOWN
Conditions: Premature Ejaculation|Erectile Dysfunction|Safety Issues
Interventions: DRUG: Dapoxetine/Tadalafil 30/20 mg film coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study
Status: COMPLETED
Conditions: Acute Heart Failure
Interventions: OTHER: Placebo|DRUG: Nesiritide|DRUG: Dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of Liver and Spleen Stiffness by RT-2D-SWE and Severity of Portal Hypertension by HVPG
Status: UNKNOWN
Conditions: Chronic Liver Diseases
Interventions: PROCEDURE: RT-2D-SWE measurement|PROCEDURE: HVPG measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available.
Status: COMPLETED
Conditions: Polycythemia Vera
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Japanese Phase 1 Trial of TH-302 in Subjects With Solid Tumors and Pancreatic Cancer
Status: COMPLETED
Conditions: Solid Tumor|Pancreatic Cancer
Interventions: DRUG: Evofosfamide|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis
Status: TERMINATED
Conditions: Cirrhosis|Ascites|Nosocomial Spontaneous Bacterial Peritonitis
Interventions: DRUG: Daptomycin + Meropenem|DRUG: Ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Usefulness of Flexible Cystoscopy for Preventing Double-J Stent Malposition After Laparoscopic Ureterolithotomy
Status: COMPLETED
Conditions: Urinary Stones|Ureteral Calculus
Interventions: DEVICE: flexible cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)
Status: RECRUITING
Conditions: Respiratory Tract Diseases|Neoplasms|Neoplasms by Histologic Type|Neoplasms, Glandular and Epithelial|Neoplasms, Squamous Cell|Tumor Virus Infections|Infections|Virus Diseases|DNA Virus Infections|Pathologic Processes|Disease Attributes|Recurrence|Papilloma|Respiratory Tract Infections|Papillomavirus Infections
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Controlled Methylphenidate for Cancer Related Fatigue: A Double Blind, Randomized, Placebo Controlled Trial
Status: COMPLETED
Conditions: Fatigue|Cancer
Interventions: DRUG: Methylphenidate|OTHER: Placebo (Sugar Pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Artery Intima-Media Thickness Following Exposure to Raloxifene or Placebo
Status: COMPLETED
Conditions: Osteoporosis, Post-Menopausal
Interventions: DRUG: raloxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections
Status: COMPLETED
Conditions: Systemic Infections
Interventions: DRUG: CAZ-AVI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Glomerular Disorders on Bone Quality and Strength
Status: RECRUITING
Conditions: Glomerular Disease|Bone Diseases, Metabolic|Bone Fracture
Interventions: RADIATION: Dual-energy X-ray absorptiometry|RADIATION: High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)|OTHER: Blood draw and Urine collection|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study on the Immune Response and Safety of a Combined Measles, Mumps, Rubella, Chickenpox Vaccine Compared to a Marketed Combined Vaccine, Given to Healthy Children 4 to 6 Years of Age
Status: ACTIVE_NOT_RECRUITING
Conditions: Measles; Mumps; Rubella; Chickenpox
Interventions: BIOLOGICAL: Investigational MMRV(H)NS vaccine|BIOLOGICAL: Investigational MM(H)RVNS vaccine|BIOLOGICAL: Investigational M(L)M(L)R(L)V(L)NS vaccine|BIOLOGICAL: Marketed MMRV_Lot 1 and Lot 2 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Predictors Of Mortality After Pelvic Fractures: A Retrospective Cohort Study From A Level-1 Trauma Center In Upper Egypt
Status: COMPLETED
Conditions: Registries|Pelvic Bone Injury|Morality
Interventions: OTHER: The presence of a pelvic fracture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutritional Support During Induction Therapy for Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Nutrition Aspect of Cancer
Interventions: PROCEDURE: No feeding tube placed|PROCEDURE: Placement of a percutaneous feeding tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Abdominal Incisional Hernia After Laparoscopic Digestive Surgery in Obese Patients (BMI>30kg/m2)
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: OBESINOV elasto-compressive belt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity of GlaxoSmithKline Biological's Human Papillomavirus (HPV) Vaccine (580299) Versus Merck's Gardasil® in Healthy Females 18-45 Years of Age
Status: COMPLETED
Conditions: Infections, Papillomavirus|Papillomavirus Vaccines
Interventions: BIOLOGICAL: GSK Biologicals HPV 16/18 vaccine 580299 (CervarixTM)|BIOLOGICAL: Gardasil ® (Merck & Co. Inc)|BIOLOGICAL: Placebo|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia
Status: RECRUITING
Conditions: Recurrent Acute Lymphoblastic Leukemia|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Burkitt Leukemia|Recurrent Burkitt Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory Acute Lymphoblastic Leukemia|Refractory Burkitt Leukemia|Refractory Burkitt Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory Lymphoblastic Lymphoma
Interventions: DRUG: Bortezomib|DRUG: Clofarabine|DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Etoposide|BIOLOGICAL: Ofatumumab|BIOLOGICAL: Pegfilgrastim|BIOLOGICAL: Rituximab|DRUG: Vincristine Sulfate Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Enalapril in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Enalapril
Interventions: DRUG: ASP1585|DRUG: enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: D-mannose for the Prevention of UTIs in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis|Recurrent Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: D Mannose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Magrolimab|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Hypotension During Cesarean Section
Status: COMPLETED
Conditions: Hypotension Symptomatic|Obstetric Anesthesia Problems|Cesarean Section Complications|Vasoconstriction
Interventions: PROCEDURE: phenylephrine infusion|PROCEDURE: norepinephrine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Custom Anterior Surfacing of Scleral Lens for Vision Quality Improvement in Patients With Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: DEVICE: Customized Scleral Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interferon Alfa-2b With or Without Bevacizumab in Treating Patients With Advanced Renal Cell Carcinoma (Kidney Cancer)
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: recombinant interferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Healthy Subjects|Functional Gastrointestinal Disorders|Laryngopharyngeal Reflux
Interventions: BEHAVIORAL: Healthy subjects : abdominal breathing|BEHAVIORAL: Laryngopharyngeal reflux disease subjects : abdominal breathing|BEHAVIORAL: Dyspepsia subjects : abdominal breathing|BEHAVIORAL: Irritable bowel disorder : abdominal breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Molecular Biology in Pancreatic Cyst Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cyst|Pancreas Cyst|Serous Cystadenoma|Mucinous Cystadenoma|IPMN
Interventions: GENETIC: Molecular biology analysis of pancreatic intra-cyst fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Endobronchial Tranexamic Acid to Reduce Bleeding in Transbronchial Cryobiopsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemorrhage Lung|Endobronchial Mass
Interventions: DRUG: Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
Status: RECRUITING
Conditions: Urinary Incontinence|Daytime Wetting|Urination Disorders|Urination Involuntary|Urologic Diseases|Lower Urinary Tract Symptoms|Urological Manifestations|Behavioral Symptoms|Mental Disorders|Elimination Disorders
Interventions: DEVICE: Sacral TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Visual Acuity Outcome Differences Between the Alcon Vivity Toric IOL and RxSight LAL+
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: DEVICE: LAL+|DEVICE: Clareon Vivity Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Hetrombopag Olamine in Chronic Idiopathic Thrombocytopenic Purpura (ITP) Patients
Status: UNKNOWN
Conditions: Chronic Idiopathic Thrombocytopenic Purpura
Interventions: DRUG: Hetrombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Toxicity Test Linked to Radiotherapy After Mastectomy and Immediate Implant Reconstruction
Status: RECRUITING
Conditions: Breast Cancer|Capsular Contracture Associated With Breast Implant
Interventions: DEVICE: NovaGray RILA Breast® test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: External Diaphragm Pacing Therapy and Correlation Analysis of Trunk Balance and Respiratory Function in Stroke Patients
Status: SUSPENDED
Conditions: Stroke|Respiratory Function
Interventions: DEVICE: External diaphragm pacing（EDP）|OTHER: Routine rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precision TMS Treatment Guided by Personalized Brain Functional Sectors (pBFS) for ASD
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: active iTBS|DEVICE: sham iTBS|BEHAVIORAL: traditional 1on1 course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers
Status: WITHDRAWN
Conditions: Vaginal Delivery
Interventions: DRUG: saline|DRUG: fentanyl/bupivacaine/epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14-21 Weeks LMP)
Status: TERMINATED
Conditions: Abortion, Induced
Interventions: DRUG: Mifepristone+misoprostol|DRUG: Placebo+Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Lateral Epicondylitis: Platelet Rich Plasma Versus Steroid Versus Saline Solution
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: BIOLOGICAL: Platelet Rich Plasma|PROCEDURE: Isotonic Saline Solutions|DRUG: Triamcinolonacetonid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Providers' Decision-Making and Reducing Information Overload Using Information Visualization in EHRs
Status: RECRUITING
Conditions: Electronic Health Records|Usability|Information Seeking Behavior|Critical Care
Interventions: DEVICE: AWARE|DEVICE: Electronic Health Record (EHR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mechanically or Kinematically Aligned Total Knee Prosthesis
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: kinematic knee prosthesis|DEVICE: biomechanic knee prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Dabigatran Etexilate Capsules With and Without Quinidine Sulfate Tablets and to Measure the Effect of Quinidine on the Absorption of Fexofenadine in Healthy Male and Female Volunteers
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate capsules|DRUG: Quinidine sulfate tablets|DRUG: Fexofenadine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AM-101 in the Treatment of Acute Tinnitus 2
Status: COMPLETED
Conditions: Tinnitus
Interventions: DRUG: AM-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exception Cementless Hip Stem
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip|Rheumatoid Arthritis|Inflammatory Arthritis|Congenital Hip Dysplasia|Avascular Necrosis of Hip|Femoral Neck Fractures
Interventions: DEVICE: Total hip arthoplasty (THA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Pasireotide LAR (Long-acting Release) in Japanese Patients With Acromegaly or Pituitary Gigantism
Status: COMPLETED
Conditions: Acromegaly|Pituitary Gigantism
Interventions: DRUG: Pasireotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Waldenstrom's Macroglobulinemia
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Alveolar Socket Preservation
Interventions: PROCEDURE: Platelet-Rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma, IDH-wildtype|MGMT-Methylated Glioblastoma
Interventions: DRUG: Temozolomide|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Benralizumab Added to Medium-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Placebo Gel|DRUG: LAS41005|DRUG: LAS106521
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
Status: ENROLLING_BY_INVITATION
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost SR|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Absorption in HIV Infected Young Adults Being Treated With Tenofovir Containing cART
Status: COMPLETED
Conditions: HIV Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 50,000 IU|DIETARY_SUPPLEMENT: Vitamin D3 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Quetiapine XR Versus Placebo as Concomitant Treatment to Mood Stabilizers in the Control of Subsyndromal Symptoms of Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)
Status: RECRUITING
Conditions: Solid Tumor
Interventions: BIOLOGICAL: Neo-T|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peritonsillar Infiltration With Levobupivacaine for Posttonsillectomy Pain
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Group S|DRUG: Group LL|DRUG: Group HL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: PF-04360365 0.1 mg/kg|BIOLOGICAL: PF-04360365 0.5 mg/kg|BIOLOGICAL: PF-04360365 1 mg/kg|DRUG: Placebo|BIOLOGICAL: PF-04360365 3 mg/kg|BIOLOGICAL: PF-04360365 8.5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Stump Closure After Distal Pancreatic Resection
Status: TERMINATED
Conditions: Distal Pancreatic Resections
Interventions: PROCEDURE: pancreatico-jejunal anastomosis|PROCEDURE: traditional anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cheese Intake,CLA and Hypercholesterolemia
Status: COMPLETED
Conditions: Modifications of LDL Cholesterol|Modifications of Enocannabinoid Levels
Interventions: DIETARY_SUPPLEMENT: CLA enriched cheese|DIETARY_SUPPLEMENT: CLA enriched cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis
Status: COMPLETED
Conditions: Aggressive Periodontitis
Interventions: DIETARY_SUPPLEMENT: Omega-3 polyunsaturated fatty acids|DRUG: Aspirin|OTHER: Placebo|PROCEDURE: Full-mouth ultrasonic debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: OG-6219|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin With Trastuzumab as First-line Therapy for Locally Recurrent or Metastatic HER2 Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited Erythromelalgia
Status: COMPLETED
Conditions: Primary Erythromelalgia|Inherited Erythromelalgia
Interventions: DRUG: XPF-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracytoplasmic Morphologically Selected Sperm Injection and Advanced Maternal Age
Status: COMPLETED
Conditions: Female Infertility
Interventions: PROCEDURE: Intracytoplasmic sperm injection (ICSI)|PROCEDURE: Intracytoplasmic morphologically selected sperm injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Quadrivalent Influenza Vaccine Among Children
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Licensed 2010-2011 Trivalent Influenza Vaccine, No Preservative|BIOLOGICAL: Investigational Trivalent Influenza Vaccine with alternate B strain, No Preservative|BIOLOGICAL: Quadrivalent Influenza Vaccine, No Preservative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax|DEVICE: Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Fecal Incontinence and Functional Defecation Disorders Using Non-instrumental Biofeedback
Status: RECRUITING
Conditions: Fecal Incontinence|Outlet Dysfunction Constipation
Interventions: BEHAVIORAL: Biofeedback|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Parathyroid Allotransplant for Severe Refractory Hypoparathyroidism
Status: RECRUITING
Conditions: Hypoparathyroidism Postprocedural
Interventions: PROCEDURE: Donor Parathyroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle intervention - diet, physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Multi-centre Study to Assess Long-term Safety and Efficacy of the Silent™ Hip Prosthesis in Primary THR
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: DEVICE: DePuy Silent™ Hip femoral prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme|Malignant Glioma|Adult Brain Tumor
Interventions: DRUG: Vorinostat|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Olokizumab in Patients With Progressive Fibrosing Interstitial Lung Diseases
Status: RECRUITING
Conditions: Lung Diseases, Interstitial
Interventions: DRUG: Subcutaneous (SC) injections of OKZ 64 milligrams (mg) every 4 weeks (q4w), one injection of 0.4 millilitre (mL)|DRUG: SC injections of Placebo every 4 weeks (q4w), one injection of 0.4 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of HEPLISAV™ a Hepatitis B Virus Vaccine in Adults on Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: BIOLOGICAL: HEPLISAV|BIOLOGICAL: Engerix-B|BIOLOGICAL: Fendrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Liposomal Bupivacaine vs Dexamethasone ISB
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DRUG: Exparel 133 MG Per 10 ML Injection|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Renal Denervation on Stress, Hypertension and Anxiety Management
Status: UNKNOWN
Conditions: Hypertension Arterial|Anxiety|Stress
Interventions: PROCEDURE: Endovascular ultrasound renal denervation (Paradise renal denervation system, ReCor, CA, USA) (RDN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Compressive Technique for Pancreatic Intestinal Anastomosis
Status: UNKNOWN
Conditions: Pancreatic Neoplasms|Pancreatitis, Chronic
Interventions: PROCEDURE: Magnetic anastomosis for pancreaticojejunostomy|PROCEDURE: Traditional hand-sewn anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p