pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Omega-3 Fatty Acids, the Omega-3 Index, and Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: 500 mg eicosapentaenoic (EPA) plus docosahexaenoic acids (DHA)|DIETARY_SUPPLEMENT: Control convenience drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compassionate Access of the Miltenyi Device for CD34+ Cell Selection
Status: RECRUITING
Conditions: Blood And Marrow Transplantation
Interventions: BIOLOGICAL: CD34 Positive Stem Cell Infusion|DEVICE: Miltenyi device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Prehabilitation to Enhance Functional Recovery After Lung Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DIETARY_SUPPLEMENT: Whey Protein Isolate Powder|BEHAVIORAL: Physical Exercise Program|BEHAVIORAL: Relaxation Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vestibular and Postural Function in Children Suspected of Balance Disorders
Status: NOT_YET_RECRUITING
Conditions: Children, Only|Vestibular Disorder|Vestibular Function Disorder|Development Delay
Interventions: DIAGNOSTIC_TEST: video Head Impulse Test|DIAGNOSTIC_TEST: Cervical Vestibular Evoked Myogenic Potential|DIAGNOSTIC_TEST: Ocular Vestibular Evoked Myogenic Potential|DIAGNOSTIC_TEST: Computerized Dynamic Posturography|OTHER: Dizziness Handicap Inventory for patient caregivers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bactericidal Permeability Protein Inhibitor and Interleukin-1beta Levels After Non-surgical Periodontal Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Avenanthramide-enriched Oats on Inflammation
Status: COMPLETED
Conditions: Inflammation
Interventions: OTHER: Avenanthramide-enriched oats|OTHER: Refined flour absent avenanthramides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: SAP001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders
Interventions: DRUG: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Post Operative Pain Following Total Knee or Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty Complications
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Fluoxetine in Juvenile Fibromyalgia
Status: COMPLETED
Conditions: Juvenile Primary Fibromyalgia Syndrome (JPFS)|Fibromyalgia
Interventions: DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Empowerment Training for COPD Patients
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Patient empowerment education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Colonoscopy With a Specific Device for the Detection of Adenomas
Status: COMPLETED
Conditions: Colorectal Cancer|Adenoma Colon
Interventions: DEVICE: Colonoscopy|DEVICE: Colonoscopy with specific device (Endocuff Vision)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Lidocaine-Prilocaine Cream|DRUG: Placebo Cream|DRUG: 1% Lidocaine Paracervical Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Transcranial Direct Current Stimulation in Appetite and Weight Control
Status: TERMINATED
Conditions: Weight Loss|Appetite Loss
Interventions: DEVICE: tDCS|DEVICE: Shame- No current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Performance of Two Neutral Oral Contrast Agents in CT Enterography
Status: UNKNOWN
Conditions: CTE
Interventions: DRUG: polyethylene glycol|DRUG: mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Follow-up Study of CD19 CAR-T Expressing IL7 and CCL19 for Relapsed or Refractory B Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma|Mantle Cell Lymphoma|Transformed Follicular Lymphoma|Primary Mediastinal Large B-cell Lymphoma
Interventions: BIOLOGICAL: CD19 CAR-T Expressing IL7 and CCL19
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bupivacaine in Tonsillectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Oglemilast in Patients With Mild to Moderate Persistent Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: oglemilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Modalities for Nursing Students
Status: COMPLETED
Conditions: Stress Reaction|Stress, Psychological|Stress, Physiological
Interventions: BEHAVIORAL: Progressive muscle relaxation|BEHAVIORAL: Guided Imagery|BEHAVIORAL: Mindfulness Meditation|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: 5-8ml 0.375% ropivacaine|OTHER: 5-8ml normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colon Preparation With 2L PEG in Combination With Lubiprostone vs 4L PEG
Status: COMPLETED
Conditions: Indication for Modification of Patient Status (Diagnosis)
Interventions: DRUG: polyethylene glycol in combination with lubiprostone|DRUG: polyethylene glycol alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm in the Brain|Primary Brain Neoplasm|Recurrent Brain Neoplasm
Interventions: PROCEDURE: Computed Tomography|RADIATION: Fluorothymidine F-18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PRogram In Support of Moms (PRISM): A Pilot Study
Status: COMPLETED
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: PRogram In Support of Moms (PRISM)|BEHAVIORAL: MCPAP for Moms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Extended-release Buprenorphine as a Novel Low-dose Induction Strategy
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Extended-release Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD-202B)
Status: COMPLETED
Conditions: Postpartum Depression
Interventions: DRUG: Placebo|DRUG: SAGE-547 60 μg/kg/h|DRUG: SAGE-547 90 μg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atazanavir Used in Combination With Other Anti-HIV Drugs in HIV-Infected Infants, Children, and Adolescents
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: ATV|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Short-Foot Exercises in Water and on Land in Pes Planus
Status: NOT_YET_RECRUITING
Conditions: Pes Planus
Interventions: OTHER: Water exercise program|OTHER: Land-based-program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Evaluation of Using the Prepuce in Feminizing Genitoplasty
Status: UNKNOWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: PROCEDURE: feminizing genitoplasty using inner surface of the prepuce as pedicled tubularized flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification and Removal of the Non Palpable Etonogestrel Contraceptive Implant
Status: COMPLETED
Conditions: Women With an ENG Contraceptive Implant
Interventions: PROCEDURE: removal of ENG implant|PROCEDURE: continuation of ING implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of OR2805, a Monoclonal Antibody Targeting CD163, Alone and in Combination With Anticancer Agents
Status: RECRUITING
Conditions: Cancer|Tumor, Solid|Malignant Neoplasm|Metastatic Cancer|Advanced Solid Tumor|Non Small Cell Lung Cancer|Melanoma|Head and Neck Squamous Cell Carcinoma|Leiomyosarcoma|Liposarcoma
Interventions: DRUG: OR2805|DRUG: Cemiplimab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: COMBINATION_PRODUCT: Concurrent Chemoradiotherapy Radiotherapy|RADIATION: Short-course Radiotherapy|RADIATION: Local dose increase of Short-course Radiotherapy|DRUG: Consolidation chemotherapy|DRUG: Adjuvant chemotherapy|PROCEDURE: TME
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Diabetes
Interventions: DEVICE: Group 1: one-hour GCT|DEVICE: Group 2: CGM placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PET and MRI Imaging of Brain Tumors Using [18F]PARPi
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Tumor|Brain Cancer
Interventions: DIAGNOSTIC_TEST: PET/MR with [18F]PARPi|DRUG: [18F]PARPi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IR Beam Used Before Peripheral Intravenous Catheter Application on Vein Visibility
Status: NOT_YET_RECRUITING
Conditions: Questionnaire
Interventions: DEVICE: randomised study, two group (experimental and control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Plerixafor Plus Donor Lymphocyte Infusion for Relapsed Acute Leukemia After Allo-HSCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Adult ALL|Relapsed Adult AML
Interventions: DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Care for Persons With ADRD and CI in SNF
Status: COMPLETED
Conditions: Advance Care Planning|Palliative Care|Skilled Nursing Facility|Cognitive Impairment
Interventions: OTHER: Palliative Care Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Diagnostic Imaging Study of 64Cu-SARTATE Using PET on Patients With Known or Suspected Neuroendocrine Tumors (DISCO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 64Cu-SARTATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CTA30X Cell Injection in Patients With Relapsed or Refractory CD19-positive B-line Hematological Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-hodgkin Lymphoma
Interventions: DRUG: CTA30X
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
Status: RECRUITING
Conditions: Ischemic Stroke|Systemic Embolism
Interventions: DEVICE: AtriClip LAA Exclusion System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Point-of-care Tests for Bacterial Vaginosis and Candidosis
Status: UNKNOWN
Conditions: Infection, Bacterial|Infection, Fungal|Preterm Birth
Interventions: DIAGNOSTIC_TEST: SavvyCheck Vaginal Yeast Test|DIAGNOSTIC_TEST: OSOM BVBLUE Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: School-based Multicomponent Intervention on Physical Fitness Related to Health and Body Image
Status: COMPLETED
Conditions: Physical Fitness|Body Image
Interventions: BEHAVIORAL: "MEXA-SE"|BEHAVIORAL: "Espelho, espelho meu"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fluorouracil Implants Used for Intraperitoneal Chemotherapy During Operation for Treatment of Phase III Gastric Cancer.
Status: UNKNOWN
Conditions: DSF
Interventions: DRUG: Fluorouracil Implants|DRUG: Xelox regimes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study To Assess The Effectiveness Of Amlodipine-Atorvastatin Combination In Hypertension And Dyslipidemia.
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Amlodipine/atorvastatin single pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges
Status: COMPLETED
Conditions: Opioid Abuse, Unspecified
Interventions: BEHAVIORAL: Opioid Naive, OR|BEHAVIORAL: At-risk for long-term use, OR|BEHAVIORAL: Long-term opioid recipient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Graft Versus Host Disease
Interventions: DRUG: Ruxolitinib+Calcineurin +Methotrexate|DRUG: Calcineurin +Methotrexate+Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Iliopsoas Positional Release Versus Conventional Exercises in the Management of Sub-acute Back Pain.
Status: RECRUITING
Conditions: Back Pain
Interventions: OTHER: Iliopsoas Positional release therapy|OTHER: Conventional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ISEO Biofeedback Tool During the Rehabilitation of Patients Treated for Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Kinematic biofeedback with ISEO motion analysis system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia
Interventions: DRUG: decitabine|DRUG: fludarabine phosphate|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: tacrolimus|DRUG: mycophenolate mofetil|BIOLOGICAL: filgrastim|RADIATION: total-body irradiation|PROCEDURE: allogeneic bone marrow transplantation|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer.
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: transanal TME|PROCEDURE: laparoscopic TME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Controlled Trial of Repeated Hands-and-Knees Positioning During Labour
Status: COMPLETED
Conditions: Pregnancy, Childbirth and the Puerperium
Interventions: OTHER: Repeated hands-and-knees positioning during labour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness Study Of The Treatment Of Attention Deficit/Hyperactivity Disorder In Brazil
Status: COMPLETED
Conditions: Attention-deficit/Hyperactivity Disorder
Interventions: DRUG: methylphenidate (Ritalin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast MRI in Women With Known or Suspected Breast Cancer and in Healthy Participants
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Perineural Dexamethasone Prolong Duration of a Nerve Block?
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ropivacaine + dexamethasone|DRUG: Ropivacaine + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of the Galilei Analyzer to Calculate the Effective Corneal Power After Corneal Refractive Surgery
Status: TERMINATED
Conditions: Cataracts
Interventions: DEVICE: Galilei dual Scheimpflug analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Value of MRD Monitoring for Adjuvant Therapy in Postoperative NSCLC
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Next-Generation Sequencing|Chemotherapy, Adjuvant|Neoplasm, Residual|Circulating Tumor DNA
Interventions: DRUG: Adjuvants, Pharmaceutic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Association of hsCAR With MAFLD and Liver Fibrosis: A Cross-sectional Study
Status: RECRUITING
Conditions: Metabolic Dysfunction-associated Fatty Liver Disease|Hepatic Steatosis|Liver Fibrosis
Interventions: OTHER: high-sensitivity C-reactive protein to albumin ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Inhaled Treatment in Sinusitis
Status: COMPLETED
Conditions: Sinusitis
Interventions: DRUG: methylprednisolone|DRUG: Budesonide|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plantar Fascia Release With Magnetic Fascia Ball
Status: COMPLETED
Conditions: Flexibility|Muscle Tightness
Interventions: OTHER: Plantar fascia self massage with a magnetic fascia ball|OTHER: Plantar fascia self massage with a non-magnetic fascia ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conventional Oral Intake vs Delayed Oral Intake With Jejunostomy Feeding After Esophagectomy (JNS Study)
Status: COMPLETED
Conditions: Esophageal Cancer|Surgery|Jejunostomy; Complications|Nutrition Related Cancer
Interventions: DIETARY_SUPPLEMENT: Jejunostomy feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypoglycemic Effects of a Dietary Supplement With Inositols, Gymnema Silvestre, Alpha-lactalbumin and Zinc.
Status: COMPLETED
Conditions: Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: EUDIAMET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Could Cervical Postural Changes Affect the Long Thoracic Nerve Electromyographic Findings?
Status: UNKNOWN
Conditions: Cervicalgia
Interventions: RADIATION: Radiography|OTHER: Electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Food Effect Study of Single Dose of Fruquintinib (HMPL-013) in Healthy Subjects
Status: COMPLETED
Conditions: Food Effect of Fruquintinib in Health Subjects
Interventions: DRUG: fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Stimulation: Inositol and Melatonin
Status: WITHDRAWN
Conditions: Infertility
Interventions: DRUG: Recombinant FSH (rFSH)|DIETARY_SUPPLEMENT: rFSH + Inositol + Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People
Status: UNKNOWN
Conditions: Mobility|Depressive Symptoms|Nutrition, Healthy|Cognitive Decline|Hearing Loss|Visual Impairment
Interventions: OTHER: VIVIFRAIL|OTHER: Nutrition|BEHAVIORAL: Psychology|BEHAVIORAL: Personal autonomy|OTHER: Community resources|OTHER: Standard recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Melanoma|Non-Small Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: GR-MD-02|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Glasdegib|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus of Childhood (Disorder)
Interventions: BEHAVIORAL: TEACH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Study to Evaluate the Efficacy and Safety of ENIA11 in Patients With Ankylosing Spondylitis
Status: TERMINATED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: ENIA11|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Yakson Touch and Kinesthetic Stimulation on the Development of High Risk Neonates
Status: COMPLETED
Conditions: Preterm Infants|Infant, Low Birth Weight
Interventions: OTHER: Yakson touch|OTHER: Conventional handling|OTHER: Kinesthetic stimulation|OTHER: Kangaroo Mother Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of L-735,524, An Inhibitor of the HIV Protease Enzyme, and Interleukin-2 in Persons Infected With HIV (NOTE: Only For Patients Who Previously Completed NIAID 93 CC-113)
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Niraparib in Metastatic Pancreatic Cancer After Previous Chemotherapy (NIRA-PANC): a Phase 2 Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Niraparib Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors
Status: COMPLETED
Conditions: Nonarteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: PDE5 Inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: DRUG: Etoricoxib (Arcoxia)|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP
Status: COMPLETED
Conditions: Sedation in ERCP
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Acamprosate|DRUG: Yohimbine|DRUG: mCPP|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Academic Detailing on Opioid Prescribing by Dentists to Adolescents and Young Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid Prescribing
Interventions: BEHAVIORAL: Academic detailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase III Trial of e-TNS for the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DEVICE: Verum Cefaly® Abortive Program device|DEVICE: Sham Cefaly® Abortive Program device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Trifarotene Cream to Assess Risk of a Trophic Acne Scar Formation
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene Cream|DRUG: Trifarotene Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Sheath of Rectus Abdominis Block Combined With the Transverse Plane
Status: UNKNOWN
Conditions: Nerve Block|Surgical Conditions
Interventions: PROCEDURE: abdominal nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Examine the Effects of 24-week Exercise Program on Functional Capacity, Cognitive Capacity, and Quality of Life in Individuals With Intellectual and Developmental Disabilities
Status: COMPLETED
Conditions: Intellectual Disabilities
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tofacitinib for the Treatment of Refractory Immune-related Colitis From Checkpoint Inhibitor Therapy- TRICK Study
Status: RECRUITING
Conditions: Immune-Mediated Colitis
Interventions: DRUG: Tofacitinib 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle-based Confocal Laser Endomicroscopy in CT-guided Percutaneous Procedures
Status: COMPLETED
Conditions: Liver Percutaneous Biopsy or Ablation|Kidney Percutaneous Biopsy or Ablation
Interventions: DEVICE: needle based confocal endomicroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Using US Medical and Pharmacy Claim Records to Compare the Resource Use, Cost, and Outcomes of People With COPD Who Take Either Tiotropium + Olodaterol or Fluticasone + Umeclidinium + Vilanterol
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Trelegy Ellipta|DEVICE: Stiolto Respimat|DRUG: Furoate/Umeclidinium/Vilanterol|DRUG: Tiotropium Bromide/Olodaterol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Ductal Adenocarcinoma|Resectable Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Cisplatin|DRUG: Fluorouracil|DRUG: Gemcitabine|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Nab-paclitaxel|DRUG: Oxaliplatin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
Status: RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Microvascular Function of GLP-1 and Its Analogues
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: GLP-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: RCT (Randomized Controlled Trial) of IV Acetaminophen for Post Operative Vaginal Reconstruction Pain
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: IV Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Time Course Comparison of Contact Lens Maintenance Systems for Hydrogel Lenses
Status: COMPLETED
Conditions: Myopia|Hyperopia
Interventions: DEVICE: Silicone Hydrogel Contact Lenses|DEVICE: 1x PMBH preserved MPS|DEVICE: 1x Polyquad/Aldox MPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dextroamphetamine as an Adjunct in Cocaine Treatment - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders|Substance-Related Disorders
Interventions: DRUG: Dextroamphetamine|DRUG: D-Amphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NR-SAFE: Safety of High-dose Nicotinamide Riboside (NR) in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Theta Burst Stimulation (cTBS) and Postoperative Delirium
Status: NOT_YET_RECRUITING
Conditions: Postoperative Delirium|Transcranial Magnetic Stimulation, Repetitive
Interventions: DEVICE: Continuous theta burst stimulation (cTBS)|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Attacks Study to Compare the Efficacy and Safety of MK-0974 With Placebo for Acute Migraine (MK-0974-031)
Status: COMPLETED
Conditions: Migraines
Interventions: DRUG: Telcagepant 140 mg|DRUG: Talcagepant 280 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uremic Toxins in the ICU: Patients After Cardiac Surgery
Status: COMPLETED
Conditions: Renal Failure
Interventions: PROCEDURE: Dialysis during 4 hours|PROCEDURE: Dialysis during 6 hours|PROCEDURE: Dialysis during 8 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan Hydrochloride Liposome Injection (LY01610) For Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: LY01610 ( Irinotecan hydrochloride liposome injection )|DRUG: LY01610 ( Irinotecan hydrochloride liposome injection ) with 5-Fu（Fluorouracil Injection）|DRUG: Irinotecan Hydrochloride Injection（CAMPTO®）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: [18F]FAraG PET Imaging for Analysis of Biodistribution in Cancer Patients Expected to Undergo Immunotherapy and/or Radiation Therapy
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: [18F]F-AraG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of MEDITOXIN® in Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: Medytoxin|BIOLOGICAL: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Assessing the Effectiveness of a Pharmacist-Delivered Program for Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking
Interventions: OTHER: Pharmacist-delivered group program for smoking cessation|OTHER: Brief standard care session for smoking cessation delivered over the telephone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Agreement Between Two Measurement Methods of Left Ventricular Outflow Tract (LVOT) Velocity Time Integral (VTI)
Status: COMPLETED
Conditions: Acute Circulatory Failure
Interventions: DEVICE: Echocardiographic exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carotid Revascularization With ev3 Arterial Technology Evolution Post Approval Study
Status: COMPLETED
Conditions: Carotid Artery Disease
Interventions: DEVICE: PROTÉGÉ™ GPS™ and PROTÉGÉ™ RX Carotid Stent Systems and SpiderFX™ Embolic Protection Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Characteristics Following a Fall
Status: UNKNOWN
Conditions: Motor Impairments|Orthopaedic Injuries|Neurological Conditions
Interventions: DEVICE: Walking aids and devices|DRUG: Muscle/nerve injection|PROCEDURE: Corrective surgery|OTHER: Physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Optical Imaging of Gastrointestinal Biopsy Samples and Their Correlation With Histology
Status: ENROLLING_BY_INVITATION
Conditions: Gastrointestinal Disease|Gastrointestinal Dysfunction
Interventions: DEVICE: Biopsy imaged by Optical imaging device.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Surgical Treatment of Peri-implantitis
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DRUG: Amoxicillin|DRUG: Chlorhexidine gluconate|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell IV Infusion for Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Sintilimab Combined With Gemcitabine/Carboplatin Regimen in the Treatment of Advanced Primary Pulmonary Lymphoepithelioma-like Carcinoma
Status: UNKNOWN
Conditions: Primary Pulmonary Lymphoepithelioma-like Carcinoma|Lung Cancer
Interventions: DRUG: Sintilimab combined with Gemcitabine and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Months Double Blind Trial to Prevent PONV in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Oral Capsule pregapalin|DEVICE: laparoscope device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Fluorescence Imaging as a Supportive Tool for Localisation of Deep Infiltrating Endometriosis During Laparoscopy
Status: COMPLETED
Conditions: Pelvic Endometriosis|Endometriosis Outside Pelvis
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
Status: TERMINATED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomised Research Comparing Acupuncture, Herbal Treatment and Artificial Tear Eye Drops in Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: PROCEDURE: Acupuncture|OTHER: Herbal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Multicenter Open-label Study to Evaluate the Safety Tolerability and PK of MEDI0680 (AMP-514) in Subjects With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: DRUG: MEDI0680 (AMP-514)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Apical Negative Pressure Irrigation System at Cleaning Lateral Canals and Reduction of Periapical Lesions After Endodontic Therapy
Status: UNKNOWN
Conditions: Root Canal Infection
Interventions: DEVICE: Irrigation Technique 1|DEVICE: Irrigation Technique 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate Study in Young Children With Developmental Disorders
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: fluticasone propionate + montelukast|DRUG: fluticasone propionate|DRUG: fluticasone propionate + salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density
Status: TERMINATED
Conditions: Osteopenia
Interventions: DRUG: bisphosphonate therapy (risedronate)|DIETARY_SUPPLEMENT: Vitamin D supplement|DIETARY_SUPPLEMENT: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find Out if Fezolinetant Helps Reduce Moderate to Severe Hot Flashes in Women in Asia Going Through Menopause
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Ventricular Catheter Used With Antimicrobial Agents on Patients With a Ventricular Catheter
Status: COMPLETED
Conditions: Hydrocephalus|Intracranial Hypertension
Interventions: DEVICE: Antibiotics-impregnated ventricular catheter (Bactiseal®)|DEVICE: Plain ventricular catheter (Codman EDS II/III)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stellate Ganglion Block in Patients With Cerebral Small Vessel Disease
Status: COMPLETED
Conditions: Dysphagia|Cerebral Small Vessel Diseases|Cognitive Impairment
Interventions: DRUG: Stellate ganglion block|BEHAVIORAL: Rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Description of Inflammatory Cell Types In Moderate to Severe Pediatric Asthma: Eosinophilic and Non Eosinophilic Sputum Markers While on Anti-IgE Therapy
Status: COMPLETED
Conditions: ALLERGIC ASTHMA
Interventions: DRUG: ANTI-IGE THERAPY (XOLAIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC