pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Perioperative Morbidity in Gyneco-oncology According to the Procedure : Coelioscopy Versus Robot-assisted Coelioscopy
Status: COMPLETED
Conditions: Cervical Cancer|Uterus Cancer|Ovarian Cancer
Interventions: PROCEDURE: gynecologic surgery - standard coelioscopy|PROCEDURE: gynecologic surgery - robot assisted coelioscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Autologous Bone Marrow Stem Cells in Treating Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: laminectomy|PROCEDURE: Intrathecal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Eplerenone on Cardiovascular Disease in HIV (MIRACLE HIV Study)
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Eplerenone|DRUG: Placebo|BEHAVIORAL: Lifestyle Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Blood Level Study of Unit Dose Budesonide
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide Inhalation Suspension|DRUG: MAP0010 low dose|DRUG: MAP0010 intermediate dose|DRUG: MAP0010 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph II Study of Cabozantinib With Pembrolizumab in Metastatic Gastric and Gastroesophageal Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Adenocarcinoma|GastroEsophageal Cancer
Interventions: DRUG: Cabozantinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib With Fludarabine and Rituximab in Relapsed and Refractory CLL and SLL
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: dasatinib|DRUG: Rituximab|DRUG: fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Hausa Oswestry Disability Index, Numeric Pain Rating Scale, Roland-Morris Disability Questionnaire, SF-12 Health Survey, Pain Catastrophizing Scale, Fear-Avoidance Beliefs Questionnaire,Global Rating of Change Scale and Back Beliefs Questionnaire in Low Back Pain Patients
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: BEHAVIORAL: Application of the initial evaluation|BEHAVIORAL: Final application of instruments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Effect of a Normal vs. High Protein Diets in Carbohydrates Metabolism in Obese Subjects With Diabetes or Prediabetes
Status: UNKNOWN
Conditions: Weight Loss|Obesity|Diabetes|Diet, Reducing|Carbohydrates|Protein
Interventions: BEHAVIORAL: Weight loss interventional study with a low-calorie 18%-protein diet|BEHAVIORAL: Weight loss interventional study with a low-calorie 35%-protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Intravitreal Ranibizumab for Recalcitrant Radiation Retinopathy
Status: COMPLETED
Conditions: Radiation Retinopathy
Interventions: DRUG: ranibizumab 2.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Cost Study of Infuse BMP 2 vs Iliac Crest Autograft for Non Union of Long Bone Fractures
Status: WITHDRAWN
Conditions: Non Union Diaphyseal Fractures
Interventions: DEVICE: Infuse Bone Morphogenic Protein (BMP) 2|PROCEDURE: iliac crest autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RESETTLE-IDPs: Life-Skills Education and Psychosocial Resilience Building for Displaced Nigerians
Status: NOT_YET_RECRUITING
Conditions: Mental Health|Psychosocial Functioning|Implementation Science|Global Health|Conflict
Interventions: BEHAVIORAL: Life Skills Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors
Status: RECRUITING
Conditions: Stroke|Endovascular Thrombectomy|Ischemic Stroke
Interventions: PROCEDURE: Endovascular thrombectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Eupasidin-s Tab.(EUPASIDIN-S) in Gastritis Patients
Status: COMPLETED
Conditions: Acute Gastritis|Chronic Gastritis
Interventions: DRUG: Eupasidin-s Tab|DRUG: Stillen Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nivolumab With CCR2/5-inhibitor or Anti-IL-8) for Non-small Cell Lung Cancer (NSCLC) or Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Hepatocellular Carcinoma
Interventions: DRUG: Nivolumab|DRUG: BMS-813160|DRUG: BMS-986253
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy
Status: TERMINATED
Conditions: Lumbar Radiculopathy
Interventions: BEHAVIORAL: Perioperative Pain Neuroscience Education|BEHAVIORAL: Perioperative Biomedical Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pralatrexate vs Observation Following CHOP-based Chemotherapy in Undiagnosed Peripheral T-cell Lymphoma Patients
Status: TERMINATED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Pralatrexate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Energy Drinks on Cardiovascular Endpoints
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Energy Drink|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence of Telmisartan / Ramipril Fixed Dose Combination Compared With the Monocomponents Given Concomitantly to Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan/Ramipril|DRUG: Telmisartan|DRUG: Ramipril capsule|DRUG: Ramipril tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronicle Offers Management to Patients With Advanced Signs and Symptoms of Heart Failure (COMPASS-HF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Chronicle Implantable Hemodynamic Monitor|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Dietary Phosphate Intake on Calciotropic Hormones and FGF23.
Status: WITHDRAWN
Conditions: Healthy|Kidney Failure, Chronic
Interventions: OTHER: Dietary|OTHER: Dietary|OTHER: Dietary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: New Technique to Assess Correct Positioning of the Right-sided Double Lumen Tube
Status: COMPLETED
Conditions: Anesthesia|Thoracic Diseases
Interventions: PROCEDURE: right-sided double lumen tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset
Status: RECRUITING
Conditions: PTSD|Chronic Pain
Interventions: PROCEDURE: Stellate Ganglion Block|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody (mAb) 216 With Chemotherapy in Adult Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia, Lymphocytic|Leukemia|Acute Lymphocytic Leukemia
Interventions: DRUG: MAb 216|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HSK29116 in Adults With Relapsed/Refractory B-cell Malignancies
Status: UNKNOWN
Conditions: Relapsed/Refractory B-Cell Malignancies
Interventions: DRUG: HSK29116
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Restriction of Foods Containing Phosphorus Additives
Status: COMPLETED
Conditions: End-stage Renal Disease|Hyperphosphatemia
Interventions: OTHER: Restriction on food containing phosphorus additives|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Trial of Monovalent Whole Virus Influenza (H1N1) Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: IVACFLU|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sudden Hearing Loss Multi-center Clinical Trial
Status: UNKNOWN
Conditions: Full-frequency Sudden Hearing Loss
Interventions: DRUG: Dexamethasone Phosphate|DRUG: Dexamethasone Phosphate|DRUG: Ginaton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can 2 Weeks of High Intensity Interval Training in Healthy 65-85 Year-olds Improve Cardiorespiratory Fitness?
Status: COMPLETED
Conditions: Cardiorespiratory Fitness
Interventions: BEHAVIORAL: HIIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of IMT ON Dyspnea, PF and Quality of Life in Patients With CABG
Status: COMPLETED
Conditions: Exercise
Interventions: OTHER: Inspiratory muscle training|OTHER: physical therapy including ankle pumps, hand pumps isometrics of upper and lower limbs.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Changes of Upper and Lower Limb Blood Flow and Vascular Resistance in Hyperbaric Spinal Anesthesia for Transurethral Resection of the Prostate (TURP) Using Duplex Ultrasonography: Comparison of Normotensive and Hypertensive Patients
Status: COMPLETED
Conditions: Transurethral Resection of the Prostate (TURP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Ablative Allo HSCT For Hematologic Malignancies or SAA
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Precancerous/Nonmalignant Condition|Small Intestine Cancer
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: graft-versus-tumor induction therapy|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG With or Without Gefitinib in Treating Patients With High-Risk Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: BCG vaccine|DRUG: gefitinib|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Daily Exercise Program on Bone Mineral Density and Cortisol Level in Preterm Infants
Status: COMPLETED
Conditions: Osteopenia of Prematurity
Interventions: PROCEDURE: Daily Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subcutaneous Alemtuzumab Combined With Oral Dexamethasone, Followed by Alemtuzumab Maintenance or Allo-SCT in CLL With 17p- or Refractory to Fludarabine
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety With CD19CAR-T for Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Relapsed Acute Lymphoblastic Leukemia|Refractory Acute Lymphoblastic Leukemia
Interventions: COMBINATION_PRODUCT: CD19 CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prefrontal Oscillations in Social Anxiety Disorder (POSAD)
Status: UNKNOWN
Conditions: Anxiety Disorders|Anxiety|Anxiety and Fear
Interventions: BEHAVIORAL: In vivo social exposure|BEHAVIORAL: Social exposure in a virtual reality setting|OTHER: EEG recording|DIAGNOSTIC_TEST: Psychometric evaluation|DIAGNOSTIC_TEST: Visual Analogue Scale of anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Flow Nasal Oxygen for Acute Hypoxemic Respiratory Failure in the Emergency Room
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DEVICE: high flow nasal cannula|OTHER: standard oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SGB Reduces the Incidence and Severity of CSA-AKI
Status: COMPLETED
Conditions: Stellate Ganglion Block
Interventions: DRUG: Stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natrecor in Pulmonary Hypertension
Status: TERMINATED
Conditions: Pulmonary Hypertension|Cancer|Lung Disease|Cardiothoracic Surgery
Interventions: DRUG: Nesiritide (Natrecor)|PROCEDURE: Right Heart Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Dose Tetravalent A, C, Y, W135 Meningococcal Polysaccharide Vaccine
Status: COMPLETED
Conditions: Infections, Meningococcal|Meningitis, Meningococcic
Interventions: BIOLOGICAL: A, C, Y, W135 meningococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Dapagliflozin as Monotherapy in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A D2 Receptor Occupancy and fMRI Study in Schizophrenic Subjects Treated With Lurasidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone 80 mg|DRUG: Lurasidone 120 mg|DRUG: Lurasidone 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Somatropin Produced by Laboratory Blausiegel Indústria e Comércio Ltda., Compared to Saizen® From Laboratory Merck Serono S.A.
Status: UNKNOWN
Conditions: GH Deficiency (GHD)|Growth Retardation
Interventions: DRUG: Somatropin|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Perfusion Assessment With Multidetector Computed Tomography
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Regadenoson (Lexiscan) [muti-detector computed tomography]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-Reported Outcomes in Long-Term Survivors of Colon and Rectal Cancers
Status: COMPLETED
Conditions: Colorectal Cancer|Fatigue|Long-term Effects Secondary to Cancer Therapy in Adults|Pain|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: Telephone interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diet and Whole-body Vibration Training on Cardiovascular and Autonomic Function
Status: COMPLETED
Conditions: Obesity|Pre-hypertension|Hypertension
Interventions: OTHER: Whole Body Vibration Training|OTHER: Hypocaloric diet|OTHER: Whole body vibration training & diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients
Status: RECRUITING
Conditions: Carotid Stenosis|Coronary Artery Disease|Valvular Heart Disease|Myocardial Infarction|Pulmonary Edema With Heart Failure
Interventions: PROCEDURE: Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Second-Line Treatment for Hypertension With Autosomal Dominant Polycystic Kidney Disease(ADPKD)
Status: UNKNOWN
Conditions: Kidney, Polycystic, Autosomal Dominant
Interventions: DRUG: Cilnidipine|DRUG: Imidapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Schulze Muscular Dystrophy Ability Clinical Study
Status: RECRUITING
Conditions: Muscular Dystrophies|Spinal Muscular Atrophy|Duchenne Muscular Dystrophy|Limb Girdle Muscular Dystrophy|FSHD|Cerebral Palsy|Becker Muscular Dystrophy
Interventions: DEVICE: Abilitech Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resveratrol on Inflammation in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Inflammation|Insulin Resistance|Other Disorders of Bone Density and Structure
Interventions: DIETARY_SUPPLEMENT: resveratrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Fibrinogen Concentrate Infusion on Blood Loss and Allogeneic Blood Conservation in Scoliosis Surgery
Status: COMPLETED
Conditions: Scoliosis; Adolescence|Bleeding|Surgery
Interventions: DRUG: Fibrinogen Concentrate Human|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples
Status: UNKNOWN
Conditions: Lymphadenopathy|Tuberculosis|Sarcoidosis
Interventions: DEVICE: Nested PCR for formalin-fixed tissues|DEVICE: Nested PCR for fresh tissues|DEVICE: Real-time PCR for fresh tissues
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect High Velocity Low Amplitude Hip Mobilization on Strength in Subjects With Lower Extremity Pathology
Status: COMPLETED
Conditions: Hip Joint|Muscle Weakness
Interventions: OTHER: Hip mobilization|OTHER: Hip manipulation simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DRUG: Perifosine|DRUG: Capecitabine|OTHER: Perifosine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma
Status: ACTIVE_NOT_RECRUITING
Conditions: Asymptomatic COVID-19 Infection Laboratory-Confirmed|Symptomatic COVID-19 Infection Laboratory-Confirmed
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Electronic Health Record Review|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MMR at 6 Months Trial
Status: COMPLETED
Conditions: Meales-mumps-rubella Vaccine
Interventions: BIOLOGICAL: MMRvaxpro|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy
Status: UNKNOWN
Conditions: Arrhythmia|ECG Changes|Hypotension
Interventions: DRUG: Intra-amniotic injection of DIGOXIN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone
Status: COMPLETED
Conditions: GCT|Giant Cell Tumor of Bone
Interventions: BIOLOGICAL: Denosumab|DIETARY_SUPPLEMENT: Calcium/Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection
Interventions: DRUG: Chloroquine|BIOLOGICAL: PfSPZ (NF54) Challenge|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment With Medroxyprogesterone Acetate Plus LNG-IUS in Young Women With Early Stage Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: DEVICE: MIrena(LNG-IUS), oral MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia
Status: RECRUITING
Conditions: Oropharyngeal Dysphagia
Interventions: DEVICE: Negative Pressure Suction Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mirror Therapy With Cutaneous Electrical Sensory Stimulation on Lower Limb Motor Functions in Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: MT|DEVICE: TENS|BEHAVIORAL: Lower-limb task-oriented training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Gait Modification to Treat Knee Osteoarthritis in Saudi Arabia: Possibilities and Acceptability.
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Pain|Biomechanical Lesion
Interventions: DEVICE: Lateral Wedge insole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Internet Stop Smoking Intervention to Usual Care on Smoking Cessation at 6 Months
Status: COMPLETED
Conditions: Cigarette Smoking|Nicotine Dependence
Interventions: BEHAVIORAL: Internet Smoking Cessation Web Site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Oxytocin|PROCEDURE: bilateral uterine artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Increasing Vitamin Intake and Physical Activity
Status: COMPLETED
Conditions: Heart Diseases|Diabetes Mellitus, Type 2|Behavior|Motivation
Interventions: BEHAVIORAL: Intervention Group (IG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of a Novel Self-Administered Cognitive Assessment Tool (CogCheck) in Patients With Mild and Major Neurocognitive Disorder Predominantly Due to Alzheimer's Disease
Status: RECRUITING
Conditions: Dementia Alzheimers|Mild Cognitive Impairment|Cognition Disorders|Neurocognitive Disorders
Interventions: DIAGNOSTIC_TEST: CogCheck
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Transfers of Fresh and Thawed Embryos in High Responder Patients
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Embryo cryopreservation|PROCEDURE: Fresh blastocyst transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Two Dry Needling Interventions for Plantar Heel Pain
Status: COMPLETED
Conditions: Plantar Fascitis|Myofacial Pain Syndromes|Trigger Point Pain, Myofascial
Interventions: OTHER: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Hepatopancreaticobiliary and Foregut Operations for Benign and Malignant Disease
Status: RECRUITING
Conditions: Hepatopancreaticobiliary and Foregut Operations
Interventions: DEVICE: da Vinci SP® Single-Port Robotic Surgical System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and PK of Once or Twice Daily Bilastine (10 or 20 mg) Compared With Placebo in the Symptomatic Treatment of SAR
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Hay Fever|Allergic Conjunctivitis|Hypersensitivity
Interventions: DRUG: Bilastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Potential Biomarkers for Foetal Brain Development After Congenital CMV Infection
Status: UNKNOWN
Conditions: Cytomegalovirus Infections|Neurologic Dysfunction
Interventions: DEVICE: amniocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DT388IL3 Fusion Protein in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Blastic Plasmacytoid Dendritic Cell Neoplasm
Interventions: DRUG: DT388IL3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tongue Dysbiosis Effects on Arterial Pressure of Periodontitis Patients
Status: UNKNOWN
Conditions: Periodontitis|Normal Blood Pressure
Interventions: DRUG: 0.12% chlorhexidine digluconate mouthwash|PROCEDURE: Periodontal instrumentation|DRUG: Placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA.
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax 100 mg d1，200 mg d2，400 mg d3-14；
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosis of Pancreatic Cancer by Purine Metabolite (Hypoxanthine, Xanthine) in Urine
Status: RECRUITING
Conditions: Pancreas Cancer|Diagnosis
Interventions: DEVICE: Purine metabolite (Hypoxanthine, Xanthine) in urine by CubeBio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tryptophan Depletion in PD Patients Treated With STN DBS
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: Tryptophan (TRP) depletion|DIETARY_SUPPLEMENT: Placebo|DEVICE: Stimulator ON|DEVICE: Stimulator OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Lumbar Plexus Block for Postoperative Pain Control After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: continuous infusion of ropivacaine via CLPB vs. CFB vs IV PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of PK/PD, Safety and Tolerability of LIK066 in Patients With Decreased Renal Function.
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: LIK066
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Dapagliflozin in Acute Heart Failure With Reduced Ejection Fraction (CODA-HFrEF)
Status: COMPLETED
Conditions: Acute Heart Failure
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol Pretreatment With Misoprostol in Second Trimester Miscarriage
Status: COMPLETED
Conditions: Miscarriage
Interventions: DRUG: Estradiol|DRUG: Placebo Oral Tablet|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol for Labour Analgesia in Low Risk Primiparous Women
Status: COMPLETED
Conditions: Pain During Labour
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Electrical Impedance Technology (EIT) for Diagnosing Liver Diseases Severity
Status: UNKNOWN
Conditions: Chronic Liver Disease|Fibrosis, Liver|Non-Alcoholic Fatty Liver Disease
Interventions: DEVICE: EIT Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass
Status: TERMINATED
Conditions: Obesity
Interventions: OTHER: RYGB|OTHER: OAGB/MGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Study of High-flux Haemodialysis and Haemodiafiltration
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: OTHER: High-flux haemodialysis|PROCEDURE: Haemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trazodone in Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Trazodone 20 mg|DRUG: Trazodone 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial Tablet
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid/Benzodiazepine Polydrug Abuse: Aim 3
Status: RECRUITING
Conditions: Opioid Abuse|Benzodiazepine Abuse|Polysubstance Abuse
Interventions: DRUG: Morphine|DRUG: Alprazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short-term Dual Antiplatelet Therapy After Deployment of Bioabsorbable Polymer Everolimus-eluting Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: P2Y12 antagonist monotherapy|DRUG: Aspirin plus P2Y12 antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Obstructive Sleep Apnea on Central Blood Pressure and Kidney and Endothelial Function
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Acute Kidney Failure|Chronic Kidney Disease
Interventions: OTHER: continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Characterization of Myocardial Interstitial Fibrosis and Cardiomyocyte Hypertrophy by Cardiac MRI in Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Aerobic exercise in treadmill|OTHER: Local strengthening exercises|OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: DRUG: D-cycloserine|BEHAVIORAL: Cognitive behavioral therapy (CBT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment.
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: 5-FU, Capecitabine, Oxaliplatin, Leucovorin.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of SARS-CoV-2 in Hospital Workers s Exposed to the Virus
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: hydroxychloroquine|DRUG: azithromycin|DRUG: hydroxychloroquine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating Techniques for Measuring Tear Production
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: 0.003% AR-15512 to be administered in both eyes|DRUG: Vehicle to be administered in both eyes|DRUG: 0.003% AR-15512 to be administered in both eyes|DRUG: Vehicle to be administered in both eyes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Peripheral Arteries Treated With SeQuent® Please P Paclitaxel Coated Balloon Catheter
Status: COMPLETED
Conditions: Stenosis|Restenosis
Interventions: DEVICE: Paclitaxel coated balloon|DEVICE: uncoated PTA catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC in Adults With Ocular Myasthenia Gravis
Status: NOT_YET_RECRUITING
Conditions: Myasthenia Gravis, Ocular
Interventions: COMBINATION_PRODUCT: Efgartigimod PH20 SC|OTHER: Placebo PH20 SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia
Status: COMPLETED
Conditions: Pain|Hyperalgesia|Inflammatory Response
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: aripiprazole (Abilify)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Allopregnanolone and Depression in Perimenopausal Women
Status: RECRUITING
Conditions: Depression
Interventions: DRUG: brexanolone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dapagliflozin on Insulin Resistance and Insulin Secretion in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MK2206 in Treating Patients With Advanced Refractory Biliary Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma|Localized Non-Resectable Adult Liver Carcinoma|Recurrent Adult Liver Carcinoma|Recurrent Gallbladder Carcinoma|Stage IV Distal Bile Duct Cancer|Stage IV Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Carcinoma|Unresectable Gallbladder Carcinoma
Interventions: DRUG: Akt Inhibitor MK2206|OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Immunogenicity and Safety of DTP-HB-Hib (Bio Farma) With Pentabio® Vaccine Primed With Recombinant Hepatitis B
Status: COMPLETED
Conditions: Immunogenicity|Safety
Interventions: BIOLOGICAL: Recombinant Hepatitis B + DTP-HB-Hib|BIOLOGICAL: Hep B + Pentabio (registered)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sphenopalatine Ganglion Block for Nasal Surery
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: Bupivacaine 0.5% Preservative-Free Injectable Solution|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis
Status: TERMINATED
Conditions: Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis
Interventions: DRUG: Placebo|DRUG: Recombinant Microbial Lipase SLV339|DRUG: Recombinant Microbial Lipase SLV339|DRUG: Recombinant Microbial Lipase SLV339
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: GSK1322322 (mesylate salt) Powder for Injection|DRUG: GSK1322322 (freebase) tablets|DRUG: GSK1322322 (mesylate salt) Powder for Oral Solution|DRUG: GSK1322322 (freebase) tablets FED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Needle Tenotomy Associated With Platelet-rich Plasma Injection Platelet-rich Plasma in the Treatment of Refractory Plantar Fasciitis: a Pilot Study of the Effect on Pain and Tolerance
Status: RECRUITING
Conditions: Plantar Fascitis
Interventions: PROCEDURE: Percutaneous tenotomy + PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncogeriatric Intervention and Follow-up at Home
Status: UNKNOWN
Conditions: Neoplasms|Geriatric Assessment|Lung Neoplasms|Colorectal Neoplasms|Head and Neck Neoplasms|Gastrointestinal Neoplasms|Geriatrics|Polypharmacy|Quality of Life
Interventions: OTHER: Geriatric Follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validating M.D. Anderson Symptom Inventory (MDASI-GI) in GI Cancer Patients Under Chemotherapy
Status: COMPLETED
Conditions: Gastrointestinal Cancer
Interventions: BEHAVIORAL: Questionnaire|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: PROCEDURE: 166Holmium TARE|DRUG: Cetuximab|DRUG: Panitumumab|DRUG: 5-Fluorouracil|DRUG: Bevacizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abatacept to Treat Steroid Refractory Chronic Graft Versus Host Disease (cGVHD)
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Composition, Nutritional and Cardiovascular Status and Lifestyle Factors of Adults Who Are on Plant-Based Diet
Status: COMPLETED
Conditions: Conditions Influencing Health Status|Body Weight|Lipid Metabolism Disorders|Uricemia|Blood Pressure Disorders|Physical Stress|Sleep Disorder|Stress, Psychological
Interventions: OTHER: Body composition, questionnaires, biochemistry and blood pressure results
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Zoledronic Acid on Femoral Bone Loss Following Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Zoledronic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Safety and Imaging Pattern of Cyclotron-produced Technetium (CTC) vs. Generator-produced Technetium (G-PERT) in People With Thyroid Disorders Who Need Surgery
Status: COMPLETED
Conditions: Thyroid Gland Diseases
Interventions: DRUG: CTC|DRUG: G-PERT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Different Front-of-Pack Nutritional Labels in Promoting Greater Adherence to the Mediterranean Diet Among Italian Consumers
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy
Interventions: OTHER: Summary Label|OTHER: Nutrient-specific label|OTHER: No label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Large Language Model on Clinical Questioning Skills
Status: RECRUITING
Conditions: Cataract|Glaucoma|Diabetic Retinopathy|Keratitis|Conjunctivitis
Interventions: DEVICE: "Digital twin patient"|BEHAVIORAL: Interaction with real patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chronic Sildenafil for Severe Diaphragmatic Hernia
Status: TERMINATED
Conditions: Hernia, Diaphragmatic|Hypertension, Pulmonary|Hypoplasia, Pulmonary
Interventions: DRUG: sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand [18F]JNJ-64511070
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [18F]JNJ-64511070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE