pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-03049423|DRUG: PF-03049423|DRUG: PF-03049423|DRUG: PF-03049423|DRUG: PF-03049423|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Caseinate|DIETARY_SUPPLEMENT: Whey protein isolate|DIETARY_SUPPLEMENT: Soy|DIETARY_SUPPLEMENT: soy+BCAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm|Primary Myelofibrosis|Essential Thrombocythemia|Polycythemia Vera
Interventions: DRUG: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Press Fit Condylar (P.F.C.) Sigma Rotating-platform High-flexion (RP-F) Versus the Press Fit Condylar (P.F.C.) Sigma Rotating-platform (RP) Knee Implants
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: PFC Sigma RP-F|DEVICE: PFC Sigma RP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CARv3-TEAM-E T Cells in Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Malignant Glioma|Recurrent Glioblastoma|Recurrent Glioma
Interventions: DRUG: CARv3-TEAM-E T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: Proton Stereotactic Body Radiation therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: DRUG: Placebo Comparator|DRUG: insulin detemir|DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of IZN-6D4 Gel for the Treatment of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: IZN-6D4 Gel|OTHER: Placebo hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fuke Qianjin Capsule in Patients With Pelvic Inflammatory Diseases
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease
Interventions: DRUG: Control Group|DRUG: Test Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Controlled Study on the Clinical Efficacy of a New Surface Modified Composite Coating Orthopedic Implant Device
Status: NOT_YET_RECRUITING
Conditions: Open Fractures, Degenerative Osteoarthritis and Degenerative Spinal Diseases
Interventions: DEVICE: Surface-modified composite coated orthopedic implants|DEVICE: conventional orthopedic implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Rituximab (MabThera/Rituxan) in Participants With Diffuse Large B Cell Lymphoma (DLBCL) or Follicular Lymphoma (FL)
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Health Intervention to Reduce Sweet Beverage Consumption in Latino Children
Status: RECRUITING
Conditions: Child Obesity|Child Development
Interventions: BEHAVIORAL: Beverage Intervention|BEHAVIORAL: Reading Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
Status: COMPLETED
Conditions: Coronary Artery Disease|Hypercholesterolemia|Monocyte Function
Interventions: DRUG: atorvastatin (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bridge to Orthotopic Liver Transplantation (OLT) - Surefire Precision vs Endhole Embolization With DEBTACE
Status: TERMINATED
Conditions: Hepatocellular Carcinoma of the Liver|Subjects Eligible for Liver Transplantation
Interventions: DEVICE: Surefire Precision Infusion System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation for Assessing the Visual Performance of Hanita Lenses Intensity SL IOL in Comparison to Alcon Panoptix IOL
Status: RECRUITING
Conditions: Cataract
Interventions: DEVICE: Intra Ocular Lens (IOL) Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture as Effective Pain Relief After Episiotomy
Status: COMPLETED
Conditions: Acupuncture, Ear|Episiotomy; Complications|Pain, Labor
Interventions: PROCEDURE: Ear acupuncture|DRUG: Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Carotid Artery Plaque Study (ACAPS)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Carotid Stenosis|Cerebral Arteriosclerosis|Cerebrovascular Disorders|Heart Diseases|Vascular Diseases
Interventions: DRUG: aspirin|DRUG: lovastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Vitamin D to Improve Endothelial Function in SLE
Status: COMPLETED
Conditions: Atherosclerosis|Systemic Lupus Erythematosus
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sintilimab, Bevacizumab, Pemetrexed, and Cisplatin for Unresectable MPeM
Status: RECRUITING
Conditions: Malignant Peritoneal Mesothelioma, Advanced
Interventions: DRUG: Sintilimab, Bevacizumab , Pemetrexed , Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HD-tDCs to Improve Upper Extremity Function in Patients With Acute Middle Cerebral Artery Stroke
Status: WITHDRAWN
Conditions: Middle Cerebral Artery Stroke
Interventions: DEVICE: Soterix MxN Neuromodulation device|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Intralesional Triamcinolone Dosing for Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Intralesional Triamcinolone 10 mg/mL|DRUG: Intralesional Triamcinolone 20 mg/mL|DRUG: Intralesional Triamcinolone 40 mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of S-588410 After Adjuvant Chemotherapy for Completely Resected Non-small- Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small- Cell Lung Cancer
Interventions: DRUG: S-588410|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Center, Phase 2 Study Evaluating Bilastine Ophthalmic Solution in the CAC® Model
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Bilastine 0.2%|DRUG: Bilastine 0.4%|DRUG: Bilastine 0.6%|DRUG: Bilastine 0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Periodontal Therapy and Oral-gut-hepatic Axis Cirrhosis: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Periodontal Diseases|Cirrhosis
Interventions: PROCEDURE: Periodontal therapy|PROCEDURE: Oral hygiene advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medigus Ultrasonic Surgical Endostapler (MUSE) Registry
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DEVICE: Medigus Ultrasonic Surgical Endostapler (MUSE) Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Uterine Fibroids With Asoprisnil(J867)
Status: COMPLETED
Conditions: Leiomyoma|Menorrhagia|Metrorrhagia
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of PD-1inhibitor (Tislelizumab) Plus Chemotherapy as Neoadjuvant Therapy for Limited-Stage Small-Cell Lung Cancer
Status: RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: DRUG: Tislelizumab (BGB-A317) Plus Chemotherapy (Cisplatin/Carboplatin and Etoposide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GO-PLAY - Early Family-Centered Intervention for Infants With High-Risk of Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: GO-PLAY|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bascom Cleft Lift Versus Limberg Flap for Sacrococcygeal Pilonidal Sinus
Status: UNKNOWN
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: Bascom Cleft Lift|PROCEDURE: Limberg Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Intravesical Instillations of BotuGelTM, Slow Release RTGel Based Botox® Formulations, in Idiopathic OAB Patients With Urinary Incontinence ("INTIMO2")
Status: WITHDRAWN
Conditions: Overactive Bladder
Interventions: DRUG: 300 IU of BotuGelTM (60ml)|DRUG: 400 IU of BotuGelTM (60ml)|DEVICE: TC-3 Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Culturally Adapted Motivational Interviewing With CBT and Mindfulness Based Relapse Prevention for Substance Use Disorder in Pakistan (CAMIAB)
Status: RECRUITING
Conditions: Substance Use Disorder (SUD)
Interventions: BEHAVIORAL: Motivational interviewing with CBT (MICBT)|BEHAVIORAL: Mindfulness based Relapse Prevention (MBRP)|BEHAVIORAL: CAMIAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Patients' Perception of Surgical Experience Based on Garment
Status: UNKNOWN
Conditions: Anxiety|Orthopedic Disorder
Interventions: DEVICE: COVR Medical Garment|OTHER: Standard Patient Gown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 3-Arm Study on G7 Acetabular Cup With Echo BiMetric Stem in Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthrosis|Pain|Arthritis
Interventions: PROCEDURE: Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EMPOWER 3: Improving Palliative Care Health Literacy and Utilization
Status: RECRUITING
Conditions: Cancer|Neoplasm Malignant
Interventions: BEHAVIORAL: Multimedia Psychoeducational Intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
Status: RECRUITING
Conditions: Pediatric Sarcoma, Refractory|Pediatric Sarcoma, Relapsed
Interventions: BIOLOGICAL: GEM/DOX + TGFBi expanded NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C/Hepatitis B Co-Infection and Chronic Hepatitis C
Status: UNKNOWN
Conditions: Hepatitis B, Chronic|Hepatitis C, Chronic
Interventions: DRUG: Peginterferon Alfa-2a plus Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onset PrevenTIon of Urinary Retention in Orthopaedic Nursing and Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Urinary Retention|Hip Fractures|Hip Arthritis
Interventions: OTHER: : A support program to facilitate implementation of evidence-based practice for postoperative urinary retention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Recanalization Rate of Acute DVT
Status: NOT_YET_RECRUITING
Conditions: Acute DVT of Lower Extremity
Interventions: DRUG: New oral anticoagulant (rivaroxaban) and Marevan (warfarin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Bellini Carcinoma|Collecting Duct Carcinoma|Renal Medullary Carcinoma
Interventions: DRUG: Pembrolizumab + Enfortumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients
Status: TERMINATED
Conditions: 2019 Novel Coronavirus Disease|2019 Novel Coronavirus Infection|2019-nCoV Disease|2019-nCoV Infection|COVID-19|COVID-19 Pandemic|COVID-19 Virus Disease|COVID-19 Virus Infection|Covid19|Coronavirus Disease 2019|SARS-CoV2 Infection|SARS-CoV-2 Acute Respiratory Disease
Interventions: DRUG: Famotidine|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Nivolumab + Relatlimab Fixed Dose Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Dietary Supplementation in Reducing Hospital Admissions for COVID-19. Randomized Clinical Trial
Status: COMPLETED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Vitamin and trace elements|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study
Status: COMPLETED
Conditions: Cocaine Dependence|Cocaine Addiction|Cocaine Abuse|Cocaine-Related Disorders
Interventions: DRUG: Clavulanic acid|DRUG: Intravenous cocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cangrelor Following Ticagrelor Loading vs Ticagrelor Loading Alone in STEMI
Status: COMPLETED
Conditions: STEMI
Interventions: DRUG: Ticagrelor 180 mg loading dose|DRUG: Cangrelor 30 mcg/kg bolus + 4 mcg/kg/min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Epinephrine-lidocaine Solution and Dexmedetomidine -Lidocaine Solution
Status: COMPLETED
Conditions: Craniotomy
Interventions: DRUG: scalp infiltration solution|DRUG: scalp infiltration solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Essential Oil-Based Preparation Administered to COVID-19 Patients
Status: NOT_YET_RECRUITING
Conditions: COVID-19 Respiratory Infection|COVID-19
Interventions: OTHER: IMMUNO19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Melanoma|Non Small Cell Lung Cancer|Gastric Cancer|Colorectal Cancer
Interventions: DRUG: HFB200603|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability and Pharmacokinetics of Oral NNZ-2591 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: NNZ-2591|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aprepitant for the Relief of Nausea in Patients With Chronic Nausea and Vomiting of Presumed Gastric Origin Trial
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer|Limited-stage Small-cell Lung Cancer|Lung Non-Small Cell Carcinoma|Stage IIIA Lung Cancer|Stage IV Lung Cancer
Interventions: OTHER: Radioconjugate|PROCEDURE: Positron Emission Tomography|PROCEDURE: Computed Tomography|PROCEDURE: FDG-Positron Emission Tomography and Computed Tomography Scan|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Detecting Sepsis in Patients With Severe Subarachnoideal Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage|Subarachnoid Hemorrhage, Aneurysmal|Sepsis Syndrome|Sepsis|Sepsis, Severe|Sepsis Bacterial
Interventions: OTHER: Sepsis detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Cataract Surgery on Sleep Quality
Status: UNKNOWN
Conditions: Cataract|Sleep
Interventions: PROCEDURE: Phacomulsification lens removal cataract surgery with neutral Intraocular lens(IOL) implantation|PROCEDURE: Phacomulsification lens removal cataract surgery with blue-blocking Intraocular lens(IOL) implantation|DRUG: Subconjunctival dexamethasone and general anesthesia|DRUG: Viscoelastic materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency
Status: TERMINATED
Conditions: Alpha-1-antitrypsin Deficiency|Liver Cirrhosis
Interventions: DRUG: Drug-Carbamazepine (Tegretol XR)|DRUG: Carbamazepine (Tegretol XR) Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cryoballoon and RF Ablation on Left Atrial Function
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon|PROCEDURE: RF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Computed Tomography (CT) Angiography Versus Standard Therapy in the Emergency Room
Status: COMPLETED
Conditions: Chest Pain
Interventions: PROCEDURE: CCTA (coronary computed tomography angiography)|OTHER: Control section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Endotoxemia|Endothelial Dysfunction|Postprandial Hyperglycemia|Gut Health
Interventions: OTHER: Bagel|OTHER: Potato
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada.
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma Resectable|Neoadjuvant Chemotherapy
Interventions: DRUG: AG regimen|DRUG: mFolfirinox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: L1 Childhood Acute Lymphoblastic Leukemia|L2 Childhood Acute Lymphoblastic Leukemia|Non-T, Non-B Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|T-cell Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: cytarabine|DRUG: methotrexate|DRUG: vincristine sulfate|DRUG: prednisone|DRUG: pegaspargase|DRUG: doxorubicin hydrochloride|DRUG: imatinib mesylate|DRUG: cyclophosphamide|DRUG: etoposide|BIOLOGICAL: filgrastim|DRUG: leucovorin calcium|DRUG: asparaginase|DRUG: therapeutic hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Videoendoscopic Drainage of Infected Pancreatic Collections
Status: COMPLETED
Conditions: Pancreatitis, Acute Necrotizing
Interventions: PROCEDURE: Videoscopic-Assisted Retroperitoneal Debridement (VARD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History Study of ENPP1 Deficiency and and the Early-onset Form of ABCC6 Deficiency
Status: UNKNOWN
Conditions: Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency|ATP-Binding Cassette Subfamily C Member 6 Deficiency|Generalized Arterial Calcification of Infancy|Autosomal Recessive Hypophosphatemic Rickets
Interventions: OTHER: No Intervention for this observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paracetamol Versus Placebo in Conjunction With Strong Opioids for Cancer Pain
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Placebo|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ondansetron VS Doxylamine and Pyridoxine in Treating Nausea of Pregnancy
Status: COMPLETED
Conditions: Vomiting of Pregnancy
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
Status: COMPLETED
Conditions: Hay Fever|Asthma|Acute Upper Respiratory Infection|Pulmonary Embolism|Pneumonia|Tuberculosis|Acute Bronchitis|Pulmonary Fibrosis|Lung Cancer|Bronchiectasis
Interventions: DIAGNOSTIC_TEST: Diagnosis by three human doctors|DIAGNOSTIC_TEST: Diagnosis by ChatGPT-3.5 (with search capabilities)|DIAGNOSTIC_TEST: Diagnosis by ChatGPT-3.5 (without search capabilities)|DIAGNOSTIC_TEST: Diagnosis by ChatGPT-4.0 (with search capabilities)|DIAGNOSTIC_TEST: Diagnosis by ChatGPT-4.0 (without search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Claude instant (with search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Claude instant (without search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Claude 2 (with search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Claude 2 (without search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Gemini Pro (with search capabilities)|DIAGNOSTIC_TEST: Diagnosis by Gemini Pro (without search capabilities)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Online Mental Health Interventions for Children and Adolescents (OMHICA)
Status: ENROLLING_BY_INVITATION
Conditions: Depression|Anxiety|Stress|Insomnia
Interventions: BEHAVIORAL: Computerized Cognitive Behavioral Therapy|BEHAVIORAL: Music Therapy|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Oral Nicotine Product in Smokeless Tobacco Users
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: oral nicotine pouch - 2 mg|OTHER: oral nicotine pouch - 4 mg|OTHER: oral nicotine pouch - 8 mg|OTHER: Smokeless tobacco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Study to Evaluate Experimental Medication BMS-986224 in Renally Impaired Participants
Status: COMPLETED
Conditions: Cardiac Failure|Myocardial Failure
Interventions: DRUG: BMS-986224
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 (SARS-CoV-2) in Urine and Semen
Status: COMPLETED
Conditions: SARS-CoV 2|Sexual Function and Fertility Disorders|Urinary Function Disorders|Urine|Semen
Interventions: DIAGNOSTIC_TEST: SARS-CoV 2 RNA PCR Urine|DIAGNOSTIC_TEST: SARS-CoV 2 RNA PCR Semen|DIAGNOSTIC_TEST: Semen Qualitative Analysis|DIAGNOSTIC_TEST: IIEF-5 questionnaire|DIAGNOSTIC_TEST: Male Sexual Health Questionnaire (MSHQ)|DIAGNOSTIC_TEST: IPSS questionnaire|DIAGNOSTIC_TEST: SECRET questionnaire|DIAGNOSTIC_TEST: Interleukin assessment in semen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment
Status: RECRUITING
Conditions: Hypertriglyceridemia|Dyslipidemia
Interventions: DRUG: Cipros 10 association|DRUG: Crestor 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tocotrienol Absorption and Distribution Under Different Fat Status
Status: COMPLETED
Conditions: Absorption
Interventions: DIETARY_SUPPLEMENT: Tocotrienol|DIETARY_SUPPLEMENT: Tocotrienol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Therapeutic Exercise and Pain Neurophysiology Education in Temporomandibular Disorders
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Disorder
Interventions: BEHAVIORAL: Therapeutic Exercise|BEHAVIORAL: Pain Neurophysiology Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kor PCI - CAD Patients Treated With PCI: Analysis of the Korean Nationwide Health Insurance Database
Status: UNKNOWN
Conditions: Coronary Artery Disease|Drug-eluting Stents|Drug-coated Balloon
Interventions: DEVICE: drug-eluting stent|DEVICE: drug-coated balloon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-Response of Aerobic Training in Women at High-Risk for Development of Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: High Risk for Developing Breast Cancer
Interventions: BEHAVIORAL: Nonlinear Aerobic Training|OTHER: Height, Weight, BMI measure|OTHER: Blood draw|OTHER: Cardiopulmonary exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine With or Without Cisplatin in Treating Patients With Unresectable Locally Advanced or Metastatic Cholangiocarcinoma or Other Biliary Tract Tumors
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regadenoson R-T Perfusion Imaging Trial
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Perfusion Abnormalities
Interventions: DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Specified Work Site Physical Activity Intervention Among Employees With Physical Heavy Work
Status: COMPLETED
Conditions: Musculoskeletal Diseases
Interventions: BEHAVIORAL: Physical activity and Health check|BEHAVIORAL: Health check only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Multicenter Clinical Study of Improved Short-course Radiotherapy Combined With CAPOX and PD-1 Monoclonal Antibody for Locally Advanced Mid-low Rectal Cancer
Status: RECRUITING
Conditions: Mid-low Rectal Cancer
Interventions: RADIATION: Short-course Radiotherapy|DRUG: Tislelizumab|DRUG: capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Accuracy of One-Step Nucleic Acid Amplification (OSNA) in Diagnosis of Lymph Node Metastases of Papillary Thyroid Carcinoma
Status: UNKNOWN
Conditions: Papillary Thyroid Cancer|Lymph Node Metastases
Interventions: DIAGNOSTIC_TEST: OSNA test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Therapeutic Strategy for Urethral Sphincter Insufficiency
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Urethral Intrinsic Sphincter Deficiency
Interventions: PROCEDURE: transplantation of the squeletic muscular cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure
Status: WITHDRAWN
Conditions: Acute Lung Injury|ALI|COVID-19
Interventions: DRUG: RLS-0071 10 mg/kg|DRUG: RLS-0071 40 mg/kg|DRUG: Placebo|DRUG: RLS-0071 10 mg/kg|DRUG: RLS-0071 40 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: SBRT 40.0 Gy|RADIATION: SBRT 42.5 Gy|RADIATION: SBRT 45.0 Gy|RADIATION: SBRT 47.5 Gy|RADIATION: SBRT 50.0 Gy|RADIATION: SBRT 52.5 Gy|RADIATION: SBRT 55.0 Gy|RADIATION: SBRT 57.5 Gy|RADIATION: SBRT 60.0 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaler Adherence in Severe Unstable Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: BEHAVIORAL: INCA feedback|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Dyspepsia: Validation of the Leuven Postprandial Distress Scale (LPDS) in a Placebo-controlled Trial
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: itopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effect of Dimethyl Fumarate on T Cells in Patients With Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Peripheral Blood Progenitor Cells Mobilisation (PBPC) With VTP195183 Plus Granulocyte-Colony Stimulating Factor (G-CSF) Compared to Mobilisation With G-CSF Alone
Status: COMPLETED
Conditions: Multiple Myeloma|Lymphoma
Interventions: DRUG: VTP195183
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hospitalization for Anorexia Nervosa (EVALuation de l'Apport de l'HOSPITalisation Pour Anorexie Mentale : EVALHOSPITAM)
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: OTHER: inpatient treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Allopregnanolone on Stress-induced Craving
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Allopregnanolone|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Entereg Laparoscopic Colon Resection Study
Status: COMPLETED
Conditions: Laparoscopic Colonic Resection
Interventions: DRUG: Entereg|DRUG: Entereg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure
Status: UNKNOWN
Conditions: Primary Ovarian Insufficiency|Menopause, Premature
Interventions: DRUG: Drospirenone and ethinyl estradiol combination (Yasmin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer Undergoing Surgical Resection
Status: TERMINATED
Conditions: Stage IA Non-small Cell Lung Cancer|Stage IB Non-small Cell Lung Cancer|Stage IIA Non-small Cell Lung Cancer|Stage IIB Non-small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|PROCEDURE: therapeutic endoscopic surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omeprazole|DRUG: Prilosec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Chronic Red Blood Cell Transfusion in Sickle Cell Disease-Associated Pulmonary Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Hypertension|Sickle Cell Disease
Interventions: OTHER: RBC transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation
Status: TERMINATED
Conditions: Recirculation|Oxygenator Blood Volume|Cardiac Output|Venoarterial Extracorporeal Membrane Oxygenation|Venovenous Extracorporeal Membrane Oxygenation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creatine, D-Ribose, B1 Vitamin, and B6 Vitamin in Ischemic Heart Disease
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DIETARY_SUPPLEMENT: Creatine, D-Ribose, B1 Vitamin, and B6 vitamin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Shenlingcao Oral Liquid for Patients With Stage II or IIIA NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Chemotherapy, Adjuvant
Interventions: DRUG: Shenlingcao Oral Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Risk in HIV Patients on Antiretroviral Therapy Therapy: The MHEART Study
Status: COMPLETED
Conditions: Cardiovascular Disease Risk in HIV Patients|Endothelial Function
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of New Custom Made Hearing Product Technology and Shell Modification
Status: UNKNOWN
Conditions: Hearing Loss, Bilateral or Unilateral
Interventions: DEVICE: hearing aid (MD class IIa) - ITE, BTE, RIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
Status: COMPLETED
Conditions: Uremic Pruritus
Interventions: DRUG: CR845 0.5 mcg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction.
Status: RECRUITING
Conditions: HIV|HIV Self-testing|Harm Reduction|Sexually Transmitted Diseases|Blood-Borne Infections
Interventions: OTHER: Our Healthbox (smart vending machine or interactive dispensing system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Assess the Effects of a Novel Application of Averaged Volume Assured Pressure Support Ventilation (AVAPS-AE) Therapy on Re-hospitalization in Patients With Sleep-Disordered Breathing With Co-morbid COPD
Status: TERMINATED
Conditions: Breathing-Related Sleep Disorder
Interventions: DEVICE: AVAPS-AE Non-invasive ventilation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia of Magnesium Sulfate in Suprascapular Nerve Block Following Shoulder Arthroscopy
Status: UNKNOWN
Conditions: Arthroscopic Shoulder Surgery
Interventions: DRUG: Bupivacaine|DRUG: Bupivacaine-magnesium|DRUG: Propofol|DEVICE: Ultrasound|DRUG: Sevoflurane|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Incorporating EMA and EMI Into CBT-I Using mHealth and Wearable Technologies
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Ecological momentary assessments/interventions with cognitive behavioural therapy for insomnia (EMA/I CBT-I)|BEHAVIORAL: Self-help cognitive behavioural therapy for insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ivermectin Against Dengue Infection
Status: UNKNOWN
Conditions: Dengue Fever
Interventions: DRUG: 2 days Ivermectin|DRUG: 3 days Ivermectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T1DTechCHW: Enhancing the Community Health Worker Model to Promote Diabetes Technology Use in Young Adults From Underrepresented Minority Groups
Status: RECRUITING
Conditions: Diabetes|Type 1 Diabetes|Young Adult|Diabetes Mellitus
Interventions: BEHAVIORAL: T1D-CATCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Sotagliflozin (SAR439954)|DRUG: Placebo|DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MR-Guided High Intensity Focused Ultrasound for Pain Management Of Osteoid Osteoma & Benign Bone Tumors in Children and Adults
Status: COMPLETED
Conditions: Osteoid Osteoma|Benign Bone Tumor|Pain
Interventions: DEVICE: MR-Guided High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CNS Infections Effect on the Inner Ear
Status: UNKNOWN
Conditions: CNS Infection|Inner Ear Hearing Loss|Vestibular Abnormality|Inner Ear Inflammation|Hearing Loss, Sensorineural
Interventions: DIAGNOSTIC_TEST: Vestibular function|DIAGNOSTIC_TEST: OAE/WBT|DIAGNOSTIC_TEST: Biomarker|DIAGNOSTIC_TEST: MOCA, eGOS|DIAGNOSTIC_TEST: Audiometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: AZD2693
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Full Mouth Erythritol Powder Air-Polishing Therapy (FM-EPAPT) Versus Traditional Ultrasonic Debridment (UD): a Randomized Controlled Study.
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: AIRFLOW® with PLUS® powder and PIEZON® scaler|DEVICE: PIEZON® scaler and rubber cup with abrasive paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral Febuxostat in Subjects With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Febuxostat|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram
Status: COMPLETED
Conditions: Pain Relief|Analgesia
Interventions: DRUG: Benzocaine|DRUG: Saline spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT