pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cinnamon and Withania on Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Cinnamomum cassia (CC) and Withania somnifera (WS) (300 mg+150mg, respectively)|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attention Training for Childhood Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Attention Modification Program|BEHAVIORAL: Attention Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole Gel Versus Terconazole Cream for Vaginal Candidiasis
Status: UNKNOWN
Conditions: Vaginal Candidiasis
Interventions: DRUG: Ketoconazole|DRUG: Terconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cardiac Rehabilitation on Health Status, Emotional Outcomes, and 90-day Readmission Rate Among Cardiac Surgery Patients
Status: COMPLETED
Conditions: Health Status|Anxiety|Depression|90-day Readmission
Interventions: BEHAVIORAL: Phase II comprehensive cardiac rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FFR Versus Angiography-Guided Strategy for Management of AMI With Multivessel Disease
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: PCI using 2nd generation drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Cancer|Squamous Cell Carcinoma|Human Papilloma Virus
Interventions: RADIATION: Radiation Therapy (IMRT or IMPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study of PB127 Ultrasound Contrast Agent in Healthy Volunteers and Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Healthy|Coronary Artery Disease
Interventions: DRUG: PB127 for Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction
Status: WITHDRAWN
Conditions: Acute Myocardial Infarction|ST Elevation Myocardial Infarction|STEMI
Interventions: DRUG: Drug: Placebo|DRUG: Drug: Injectable Thymosin beta 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengthening Facility-based Intrapartum/Immediate Newborn Care to Reduce Mortality of Preterm Infants in Migori County, Kenya and Busoga Region, Uganda
Status: COMPLETED
Conditions: Pregnancy Complications|Preterm Labor|PreTerm Birth|Stillbirth|Low Birth Weight
Interventions: BEHAVIORAL: data strengthening|BEHAVIORAL: modified Safe childbirth checklist - control|BEHAVIORAL: modified Safe childbirth checklist - enhanced|BEHAVIORAL: PRONTO training|BEHAVIORAL: QI cycles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Effect of PBF-680 in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: PBF-680 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: China Refractory Obsessive-Compulsive Disorder Deep Brain Stimulation Study
Status: WITHDRAWN
Conditions: Obsessive Compulsive Disorder
Interventions: DEVICE: Bilateral Nucleus Accumbens DBS (Suzhou Sceneray)|DEVICE: Sham Bilateral Nucleus Accumbens DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma (RRMM)
Interventions: OTHER: Teclistamab|OTHER: Talquetamab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antipsoriatic Effect of a Topical Formulation for the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: SPS4251 Ointment|DRUG: Placebo|DRUG: Daivonex® ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Joint Preserving Surgery for Correction of Spasmodic Flat- Foot in Skeletally Mature Foot
Status: UNKNOWN
Conditions: Flat Foot; Rigid|Flat Foot; Spastic
Interventions: PROCEDURE: Joint Preserving Surgery in spasmodic flat foot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetics of AFOLIA and US Gonal-f® RFF Redi-ject After Single Subcutaneous Application
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Afolia|DRUG: US Gonal-f®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Surgical Versus Non-surgical Treatment of Displaced Proximal Humerus Fracture in Adults Aged 50 to 65 Years
Status: RECRUITING
Conditions: Proximal Humeral Fracture|Shoulder Fractures
Interventions: PROCEDURE: Surgical|PROCEDURE: Non surgical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Food Effect of SYHA1813 Oral Solution in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: SYHA1813 oral solution (2.0g:25mg)|DRUG: SYHA1813 oral solution (20ml:200mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioenergy, Depression, Anxiety and Stress After Liver Transplantation
Status: TERMINATED
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: Bioenergy application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of FiO2 on PaO2/FiO2 Ratio
Status: UNKNOWN
Conditions: PaO2/FiO2 Ratio
Interventions: DRUG: Modulation of FiO2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Community Pharmacists and Opioid Misuse
Status: COMPLETED
Conditions: Opioid Misuse
Interventions: BEHAVIORAL: Brief Intervention Medication Therapy Management|BEHAVIORAL: Standard Medication Counseling (SMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence in the Detection of Right Sided Colonic Polyp in Different Operator Experience
Status: RECRUITING
Conditions: Colon Polyp
Interventions: DEVICE: Artificial intellegence. CADe syste,|DEVICE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Bioequivalence Study of Rotigotine Transdermal Patch With Two Different Formulations in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Rotigotine PR 2.1.4|DRUG: Rotigotine PR 2.2.1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Lavender Aromatherapy on Post-Operative Nausea and Vomiting Among Laparotomy Patients
Status: NOT_YET_RECRUITING
Conditions: Postoperative Nausea and Vomiting
Interventions: OTHER: aromtherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using the Deep Temporal Nerves Versus the Masseteric Nerve for Correction of Eyelid Paresis.
Status: UNKNOWN
Conditions: Facial Paresis
Interventions: PROCEDURE: Deep temporal nerves|PROCEDURE: massteric nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Infection
Interventions: BIOLOGICAL: Allogeneic umbilical cord mesenchymal stem cells|BIOLOGICAL: Controlled normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Albumin on Acute Renal Dysfunction Associated With Cardiac Surgery Under Extracorporeal Circulation
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Human albumin|DRUG: Plasmalyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Resectable Pancreatic Cancer
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|DEVICE: NovoTTF-200T(P)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab + Paclitaxel/ Ramucirumab (RAP) as Second Line Treatment in Gastro-esophageal Adenocarcinoma
Status: UNKNOWN
Conditions: Gastroesophageal Junction Adenocarcinoma|Adenocarcinoma of the Stomach
Interventions: DRUG: Avelumab|DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|CTS|Carpal Tunnel
Interventions: DEVICE: CTR-US|PROCEDURE: mOCTR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|PreDiabetes|Metabolic Syndrome
Interventions: DEVICE: The Cleerly CAD Staging System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Factor VII, Prothrombin Complex Concentrate, and Fresh Frozen Plasma in Warfarin-Related Intracranial Hemorrhage
Status: TERMINATED
Conditions: Intracranial Hemorrhage
Interventions: DRUG: Recombinant Activated Factor VII (rFVIIa)|DRUG: Prothrombin Complex Concentrate|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Blood Pressure Management and Dexamethasone in Lung Cancer Surgery
Status: RECRUITING
Conditions: Lung Cancer|Surgery|Blood Pressure Management|Dexamethasone|Overall Survival|Postoperative Complications
Interventions: DRUG: Dexamethasone|OTHER: Targeted blood pressure management|DRUG: Placebo|OTHER: Routine blood presure management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women
Status: RECRUITING
Conditions: Chronic Hepatitis b|Tenofovir Alafenamide Fumarate
Interventions: DRUG: Tenofovir Alafenamide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Side Effects of Commonly Prescribed Medications in Pediatric Migraine
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: propranolol|DRUG: zonisamide|DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Agomelatine Treatment of Depression in Schizophrenia (AGOPSYCH)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Delusional Disorder
Interventions: DRUG: agomelatine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Status: COMPLETED
Conditions: Ankle Disease|Ankle Injuries|Foot Injury|Foot Diseases
Interventions: DRUG: 0.9 % Sodium Chloride|DRUG: 0.1mg/kg Dexamethasone|DRUG: 0.05mg/kg Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life and Personality Traits in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Quality of Life
Interventions: OTHER: The World Health Organization Quality of Life (WHOQOL) -BREF|OTHER: The Satisfaction With Life Scale - SWLS|OTHER: Big Five Inventory - BFI; John in Srivastava, 1999
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Feasibility, Health and Behavioral Impact of Mid-Ohio Farmacy + WW
Status: COMPLETED
Conditions: Food Insecurity|Overweight and Obesity|Produce Prescription|Weight Change, Body
Interventions: BEHAVIORAL: Mid-Ohio Farmacy (produce prescription) + WW International Coaching (In person and/or Virtual)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy and Maintain Effect of OPR on OSA Patients After Palatal Surgery
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: Palatal surgery|BEHAVIORAL: Oropharyngeal rehabilitation|COMBINATION_PRODUCT: Palatal surgery combined oropharyngeal rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Front-of-package Labelling Schemes: an Experimental Study
Status: COMPLETED
Conditions: Diet Modification|Cardiovascular Diseases|Nutrition
Interventions: OTHER: Nutrition Rating System - Traffic Light|OTHER: Nutrition Rating System - Health Star|OTHER: Nutrition Rating System - Warning Label|DEVICE: Smartphone application FoodFlip Device®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Drug: Budesonide/formoterol (Symbicort Turbuhaler|DRUG: Drug: ipratropium (AtroventTM)|DRUG: theophylline SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: clarithromycin treatment for prophylaxis of bronchopulmonary dysplasia|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to Bone
Status: COMPLETED
Conditions: Prostate Cancer Metastatic to Bone
Interventions: DRUG: Radium Ra 223 Dichloride|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-disciplinary Diagnosis and Treatment Process and Evaluation System for Children With Sleep Disordered Breathing and Malocclusion
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Malocclusion
Interventions: DRUG: Mometasone Furoate Nasal Spray|PROCEDURE: tonsillar adenoidectomy|PROCEDURE: Maxillary expander plus Twin-Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Musicotherapy in the Reduction of Fatigue in Women With Breast or Gynecological Cancer Under Radiotherapy
Status: COMPLETED
Conditions: Breast Cancer|Uterine Cancer|Ovarian Cancer
Interventions: BEHAVIORAL: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation
Status: ENROLLING_BY_INVITATION
Conditions: Atrophy of Edentulous Alveolar Ridge
Interventions: PROCEDURE: prefabricated CAD-CAM allogeneic bone block hydrated using hyaluronic acid|PROCEDURE: prefabricated CAD-CAM allogeneic bone block sterilized hydrated using saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Postoperative Bronchoscopy on Pulmonary Complications After Anatomical Lung Resections.
Status: RECRUITING
Conditions: Postoperative Complications|Thoracic Surgery
Interventions: PROCEDURE: Postoperative systematic bronchial aspiration.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children
Status: COMPLETED
Conditions: Encephalitis, Tick-borne
Interventions: BIOLOGICAL: Formaldehyde inactivated, sucrose gradient purified TBE virus antigen, strain Neudörfl
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sacituzumab Govitecan Plus EV in Metastatic UC
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Cancer|Metastatic Urothelial Carcinoma|Metastatic Urothelial Carcinoma of the Renal Pelvis and Ureter|Bladder Cancer
Interventions: DRUG: Sacituzumab Govitecan (SG)|DRUG: Enfortumab vedotin-ejfv (EV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Olfactory Training Improve Olfaction in a Population With Normal Sense of Smell?
Status: COMPLETED
Conditions: People With Normal Sense of Smell
Interventions: BEHAVIORAL: intensive olfactory training|BEHAVIORAL: ordinary olfactory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: R(+) pramipexole dihydrochloride monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAGRISSO (Osimertinib) in NSCLC Patients in Whom T790 Mutations Are Detected by Liquid Biopsy
Status: COMPLETED
Conditions: NSCLC
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity
Status: COMPLETED
Conditions: Obesity|Vitamin D Deficiency|Hypertension
Interventions: DIETARY_SUPPLEMENT: Vitamin D (cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Examining the Effectiveness of an Early Psychological Intervention to Prevent Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure (PE) Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ProSat - Long Term Effect of Probiotics on Satiety
Status: COMPLETED
Conditions: Obesity|Appetite Regulation
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Cognitive/Functional Effects|Fatigue|Neurotoxicity|Psychosocial Effects of Cancer and Its Treatment
Interventions: DRUG: modafinil|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Adults
Interventions: OTHER: High Linoleic Acid Healthy Cookies|OTHER: High Oleic Acid Healthy Cookies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole-body Vibration Training to Reduce the Symptoms of Chemotherapy-induced Peripheral Neuropathy
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: BEHAVIORAL: Whole-body vibration training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DRUG: Phenylephrine HCl Extended Release|DRUG: Phenylephrine HCl Immediate Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study to Compare the Bioavailability of Two Fluticasone Propionate 0.005% Topical Ointments
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fluticasone Propionate 0.005% Ointment-Reference Product|DRUG: Fluticasone Propionate 0.005% Ointment-Test product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Efficacy and Safety Between Eperisone a BID and a TID Regimen in Acute Low Back Pain Patients
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Epirisone 50mg or placebo TID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab (MEDI4736) Plus Cediranib in Patients With Metastatic Uveal Melanoma
Status: WITHDRAWN
Conditions: Uveal Melanoma|Metastatic Cancer
Interventions: DRUG: Cediranib Maleate|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Repeated Administration of NurOwn (MSC-NTF Cells) in Participants With Progressive MS
Status: COMPLETED
Conditions: Multiple Sclerosis, Chronic Progressive
Interventions: BIOLOGICAL: NurOwn (MSC-NTF cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
Status: ENROLLING_BY_INVITATION
Conditions: Intra Cerebral Hemorrhage|ICH - Intracerebral Hemorrhage|ICH|Hemorrhage|Stroke|Clot (Blood); Brain|Clot Blood|Cognitive Decline|Cognitive Impairment|Survivorship|Memory Impairment|Motor Activity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early High-flow Oxygen Therapy With nebuLized Beta-2-agonist Using a Vibrating Mesh for the Management of Moderate to Severe Asthma Exacerbation in the Emergency Department
Status: RECRUITING
Conditions: Moderate Asthma Exacerbation|Severe Asthma Exacerbation
Interventions: DEVICE: Standard Nebulization|DEVICE: A - Vibrating mesh nebulization|DEVICE: B - Vibrating mesh nebulisation and high-flow nasal cannula heated and humidified oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDEAL Study: Identification of the Determinants of the Efficacy of Arterial Blood Pressure Lowering Drugs
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Indapamide (T2)|DRUG: Perindopril (T1)|DRUG: Placebo of Perindopril (P1)|DRUG: Placebo of Indapamide (P2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Point-of-Care Multiplex for Adult Patients With Severe Community-acquired Pneumonia
Status: UNKNOWN
Conditions: Community-acquired Pneumonia|Critical Illness
Interventions: DIAGNOSTIC_TEST: Provide the panel report to the primary care physician
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-operative Immuno-Nutrition in Radical Cystectomy
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|DIETARY_SUPPLEMENT: Standard Oral Nutritional Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Ixmyelocel-T (Formerly Cardiac Repair Cell [CRC] Treatment) in Patients With Heart Failure Due to Dilated Cardiomyopathy (IMPACT-DCM)
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: BIOLOGICAL: Ixmyelocel-T|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benfotiamine in Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Benfotiamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Acupuncture Analgesia on Experimental Dental Pain - A Psychophysical Study (Phase1)
Status: COMPLETED
Conditions: Experimental Dental Pain
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham-Acupuncture|PROCEDURE: No Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Protege Extension Trial - Long Term Follow Up Trial for Subjects Who Completed the Protege Study (CP-MGA031-01)
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Blood samples for safety|BEHAVIORAL: Patient reported outcome questionnaires|DIAGNOSTIC_TEST: Analysis of T-cell subsets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Hypnosis in Fibromyalgia
Status: COMPLETED
Conditions: Analgesia|Anxiety|Depression|Hypnosis
Interventions: BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Biomarkers of Hand Function and Recovery After Injury
Status: TERMINATED
Conditions: Stroke|Spinal Cord Injuries
Interventions: OTHER: Rehabilitation using motorized glove for stroke and spinal cord injury|OTHER: Functional MRI for stroke and spinal cord injury|OTHER: Transcranial magnetic stimulation (TMS) for stroke and spinal cord injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-Intensity vs Low-Intensity NPPV in Patients With an AECOPD: The HAPPEN Trial
Status: TERMINATED
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: High-intensity NPPV|DEVICE: Low-intensity NPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Trial of Operative Treatment of Distal Pediatric Forearm Fractures With Biodegradable Nails and K-wires
Status: UNKNOWN
Conditions: Fracture Wrist
Interventions: PROCEDURE: Distal radial metaphyseal fracture fixation with percutaneous K-wires|PROCEDURE: Distal radial and/or ulnar metaphyseal fracture fixation with bidegradable PLGA-based (Activa Im-Nail) implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Physical Activity Program Among Breast Cancer Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer Female|Survivorship|Health Behavior
Interventions: BEHAVIORAL: WATSOCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy
Status: RECRUITING
Conditions: Chordoma|Chondrosarcoma|Ewing Sarcoma|Osteosarcoma
Interventions: RADIATION: Proteus ONE one daily beam|RADIATION: Proteus ONE two daily beam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping in Patients After Lumbar Disc Surgery
Status: COMPLETED
Conditions: Lumbar Disc Surgery|Post Operative Pain
Interventions: OTHER: Kinesio taping|OTHER: placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Efficacy and Safety Trial of Serostim® in the Maintenance of the Treatment Effect Obtained During the Study of Serostim® in Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome
Status: COMPLETED
Conditions: Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)|Human Immunodeficiency Virus Infections
Interventions: DRUG: Serostim®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|DRUG: Placebo|DRUG: Androgen Deprivation Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Exacerbations Treated With BenRAlizumab (The ABRA Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma|COPD
Interventions: DRUG: Benralizumab|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Survivorship and Patient Outcomes of Primary Total Hip Arthroplasty With the Ovation Hip System
Status: UNKNOWN
Conditions: Joint Diseases|Osteoarthritis, Hip|Rheumatoid Arthritis|Psoriatic Arthritis|Avascular Necrosis of Hip
Interventions: DEVICE: Routine Total Hip Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib (ACP-196)|DRUG: Rituximab|DRUG: Idelalisib|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chronocort® With Standard Glucocorticoid Therapy in Patients With Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Chronocort®|DRUG: standard glucocorticoid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eating Disinhibition and Vagal Tone and the Postprandial Response to Glycaemic Load
Status: COMPLETED
Conditions: Hunger
Interventions: DIETARY_SUPPLEMENT: Isomaltulose|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Sweetened water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Retinopathy|Diabetic Macular Edema
Interventions: DRUG: Intravitreal injection (triamcinolone acetonide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Extraluminal Use of the Bronchial Blocker of Univent Tube
Status: COMPLETED
Conditions: Therapeutic Procedural Complication
Interventions: DEVICE: Extraluminal use of Univent bronchial Blocker|DEVICE: Innerluminal use Univent bronchial Blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipid Profile Response to Electroacupuncture Stimulation in Non Alcoholic Fatty Liver Patients
Status: COMPLETED
Conditions: Fatty Liver , Electroacupuncture, Lipid Profile
Interventions: DEVICE: electro-acupuncture stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Unified Index to Predict the Success Probability of Myopia Control
Status: WITHDRAWN
Conditions: Myopia, Progressive
Interventions: DEVICE: orthokeratology lens|DEVICE: multifocal soft contact lens|DEVICE: Single vision spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of FlutiForm® Versus Fluticasone Plus Formoterol in Adult Subjects With Severe Asthma
Status: COMPLETED
Conditions: Asthma, Bronchial
Interventions: DRUG: Flutiform 250/10 micrograms|DRUG: Flutiform 50/5 micrograms|DRUG: Flixotide pMDI 250 mcg + foradil pMDI 24 micrograms|DRUG: Flixotide pMDI 250 micrograms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Discovery of New Cancer in the 1-year Follow-up After Ischemic Stroke in Patients at Risk: The INVISIBLE-1 Study
Status: RECRUITING
Conditions: Cancer-related Stroke|Paraneoplastic Coagulopathy|Occult Cancer|Ischemic Stroke|Embolic Stroke of Undetermined Source|D-dimer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Therapy for Osteoarthritis Pain: How Does it Work?
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Muscle Strengthening Training|BEHAVIORAL: Behavioral graded activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Amlodipine besylate tablets (trade name: Norfloxacin ®）|DRUG: Amlodipine besylate controlled-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Noninvasive Transcranial Direct Current Stimulation to Improve Executive Functions in Stroke Patients. MODUL-EXE Clinical Trial.
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab 200 mg|RADIATION: Radiotherapy 60 Gray/day|RADIATION: Radiotherapy 66 Gray/day|RADIATION: Radiotherapy 70 Gray/day|DRUG: Cisplatin 100 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive Age
Status: COMPLETED
Conditions: Iron|Cerebral Blood Flow|Energy Metabolism|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Iron bis-glycinate chelate and vitamin C|DIETARY_SUPPLEMENT: Iron bis-glycinate chelate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Speech Performance and Clinic Efficiency With Remote Care Compared With Standard of Care in Adults With a Cochlear Implant in the First 12 Months Post-activation
Status: RECRUITING
Conditions: Hearing Loss
Interventions: PROCEDURE: Cochlear™ Remote care|PROCEDURE: Standard of care|DEVICE: Cochlear Implant CI600 Series, CI500 Series or Freedom Series and Sound processor Nucleus 7 or Kanso 2 (or latest compatible Sound Processor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea
Status: COMPLETED
Conditions: Diarrhea|Fever|Vomiting|Abdominal Pain
Interventions: DRUG: azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual-sided Hypoglossal neRvE stimulAtion for the treatMent of Obstructive Sleep Apnea (DREAM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Genio™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thiotepa, Busulfan and Fludarabin for pt With Refractory/Early Relapsed Aggressive B-cell Non Hodgkin Lymphomas
Status: UNKNOWN
Conditions: B-cell Lymphoma Refractory
Interventions: DRUG: Thiotepa|DRUG: Busulfan|DRUG: Fludarabin|PROCEDURE: transplant (HCT)|RADIATION: Cytoreduction|DRUG: Immunosuppression|DRUG: Cyclosporine|DRUG: Methotrexate|DRUG: ATG|PROCEDURE: Collection and infusions of Donor PBSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults
Status: NOT_YET_RECRUITING
Conditions: Trichuris Infection
Interventions: DRUG: Oxfendazole|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Early Removal of Chest Tubes After Thoracoscopic Lung Biopsies
Status: UNKNOWN
Conditions: Non-Neoplastic Thoracic Disorder|Lung Diseases
Interventions: PROCEDURE: Chest tube removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Mixed-methods Approach to Explore Health Communication in Hospice Out-Patient Settings
Status: ENROLLING_BY_INVITATION
Conditions: Communication|Palliative Care
Interventions: BEHAVIORAL: The LINE Chatbot
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Cardiac MRI in the Follow up Assessment of Patients With PAH (EVITA)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: PROCEDURE: Cardiac magnetic resonance imaging (cMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Incorporating Nutrition, Vests, Education, and Strength Training in Bone Health (INVEST in Bone Health)
Status: COMPLETED
Conditions: Weight Loss|Bone Health
Interventions: DEVICE: Vest|BEHAVIORAL: Resistance Exercise Training|BEHAVIORAL: weight loss program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate
Status: RECRUITING
Conditions: Nicotine Dependence
Interventions: DRUG: low dose Nicotine|DRUG: high dose Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TSCS for Acute SCI
Status: RECRUITING
Conditions: Acute Spinal Cord Injury|Blood Pressure|Hypotension
Interventions: PROCEDURE: TSCS Mapping|DEVICE: Transcutaneous spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Misoprostol With Intracervical Foley Catheter in Induction of Labor
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DEVICE: Transcervical Foley catheter|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2b and Nilotinib for Augmentation of Complete Molecular Response in Chronic Myeloid Leukaemia
Status: COMPLETED
Conditions: Chronic Myeloid Leukaemia
Interventions: DRUG: Nilotinib, Pegylated interferon alpha-2b, Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Provision of Antioxidant Therapy in Hemodialysis (PATH) Study
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DRUG: Alpha, gamma, beta, and delta (mixed) tocopherols|DRUG: Alpha lipoic acid|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy
Status: COMPLETED
Conditions: Gingival Diseases|Gingivitis|Autoimmune Diseases|Oral Lichen Planus
Interventions: OTHER: papillary gum biopsies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Demonstrate the Relative Bioavailability of Geneva and Dista (Prozac) 20 mg Fluoxetine Hydrochloride Capsules (Pulvules) In Healthy Adult Males Under Fasting Conditions
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Fluoxetine Hydrochloride 20 mg Capsules (Geneva Pharmaceutical, Inc.)|DRUG: Prozac Fluoxetine Hydrochloride 20 mg Capsules (Dista)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polycystic Ovary Syndrome and Exercise
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: High Intensity Interval Training|BEHAVIORAL: Continuous Aerobic Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Acamprosate in Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Acamprosate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of Kanasina Gulabi, a Pilot Peer Support Intervention for Young Adults With Type 2 Diabetes in Mysore District, South India
Status: COMPLETED
Conditions: Type 2 Diabetes|Quality of Life|Depression|Stigma, Social|Behavior, Health
Interventions: BEHAVIORAL: Kanasina Gulabi
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE