pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gabapentin Treatment of Benzodiazepine Dependence
Status: TERMINATED
Conditions: Benzodiazepine Dependence
Interventions: DRUG: gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Grounding Effect on Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Insomnia|Depression, Anxiety
Interventions: DEVICE: Grounding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI
Status: RECRUITING
Conditions: Iron Deficiency Anemia Due to Blood Loss|Aortic Stenosis
Interventions: DRUG: IV Sodium Ferric Gluconate Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Acute Increase in Plasma IL-6 on Glucose Tolerance When a Meal is Administered Intraduodenally
Status: COMPLETED
Conditions: Postprandial Glucose Homeostasis
Interventions: PROCEDURE: Infusion of a liquid meal intraduodenally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study
Status: NOT_YET_RECRUITING
Conditions: Ovarian Stimulation|Quality of Life|Preimplantation Genetic Testing|Fertility Preservation
Interventions: DRUG: Elonva®|DRUG: Puregon®|DRUG: Orgalutran®|DRUG: Gonapeptyl®|DRUG: Cerazette®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
Status: COMPLETED
Conditions: Metastatic Myxoid Liposarcoma|Metastatic Round Cell Liposarcoma|Metastatic Synovial Sarcoma|Recurrent Mycosis Fungoides and Sezary Syndrome|Refractory Mycosis Fungoides and Sezary Syndrome|Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage II Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage III Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7|Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7|Unresectable Synovial Sarcoma
Interventions: BIOLOGICAL: Interferon Gamma-1b|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrogel Coating to Reduce Post-surgical Infection After Joint Arthroplasty
Status: RECRUITING
Conditions: Arthritis|Traumatic Arthritis|Avascular Necrosis
Interventions: DEVICE: Hydrogel coating|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies
Status: UNKNOWN
Conditions: Dentofacial Deformities
Interventions: DRUG: Oral Melatonin 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Exposure Study in Smokers Using THS 2.2 With 5 Days in a Confinement Setting.
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: Tobacco Heating System (THS 2.2)|OTHER: Smoking abstinence (SA)|OTHER: Conventional cigarette (CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Living Well After Breast Surgery
Status: COMPLETED
Conditions: Breast Cancer Female|Stage I Breast Cancer|Stage II Breast Cancer|Stage III Breast Cancer|Ductal Carcinoma in Situ|Ductal Breast Carcinoma|Lobular Breast Carcinoma
Interventions: OTHER: Breast reconstruction decision aid|OTHER: Educational website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of the Knee-T-nol Anterior Cruciate Ligament (ACL) Prosthesis
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DEVICE: Knee-T-Nol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Vs. HFA MDI Propellant in Healthy Participants
Status: COMPLETED
Conditions: Mucociliary Clearance
Interventions: DRUG: HFO MDI|DRUG: HFA MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peer-led Psycho-education for Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Peer-led psycho-education group|BEHAVIORAL: Profession-led psycho-education group|OTHER: Routine psychiatric care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Rollover Study for Subjects Who Completed Participation in the VRX496-USA-05-002 Trial
Status: UNKNOWN
Conditions: HIV Infections
Interventions: GENETIC: VRX496-transduced autologous CD4 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness on Psychophysiological Stress in a Population With Elevated Stress Symptoms
Status: COMPLETED
Conditions: Psychological Stress|Physiological Stress
Interventions: BEHAVIORAL: Headspace Basics Program|BEHAVIORAL: Headspace Breathing Exercises|BEHAVIORAL: Headspace Stress Program|BEHAVIORAL: Active Control (Audiobook)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immune Response Study of the Vaccine ALVAC vCP1452 Alone or in Combination With AIDSVAX B/B
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)|BIOLOGICAL: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil
Status: COMPLETED
Conditions: Upper Respiratory Infection|Acute Otitis Media
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Improvement of Intraoperative Neuromonitoring of Recurrent Laryngeal Nerve
Status: COMPLETED
Conditions: Thyroid Intra-Operative Injury
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Grand Valley State University (GVSU) Skills on Wheels
Status: RECRUITING
Conditions: Spina Bifida|Cerebral Palsy|Genetic Disease|Spinal Cord Injuries|Gross Motor Development Delay|Motor Skills Disorders
Interventions: OTHER: Manual Wheelchair Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compression Therapy of the Lower Limbs in Patients With Decompensated Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: UrgoK2 / UrgoK2 Lite|OTHER: Controll
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Videolaryngoscopy in Small Infants
Status: COMPLETED
Conditions: Surgery|Anesthesia, Endotracheal
Interventions: DEVICE: Video Laryngoscopy for ET placement|DEVICE: Direct Laryngoscopy for ET Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The PATH Home Trial: A Comparative Effectiveness Study of Peripartum Opioid Use Disorder in Rural Kentucky
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Abstinence Syndrome
Interventions: BEHAVIORAL: Telemedicine|BEHAVIORAL: Group Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety & Efficacy of Intravitreal Aflibercept Injection in Patients With Persistent Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: Intravitreal Aflibercept Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 2 Week, Crossover Trial of Dietary Nitrate in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Dietary nitrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery
Status: COMPLETED
Conditions: Microvascular Decompression Surgery|Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: 0.9% Sodium Chloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Placebo|DRUG: Rontalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide (INO) for the Prevention of Bronchopulmonary Dysplasia (BPD) in Preterm Infants
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Inhaled Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Pantoprazole Sodium DR Tablets 40 mg of Dr. Reddy's Laboratories Limited Under Fed Condition
Status: COMPLETED
Conditions: FED
Interventions: DRUG: Pantoprazole Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Bacteria on Oral Candida in Frail Elderly
Status: COMPLETED
Conditions: Candidiasis
Interventions: DIETARY_SUPPLEMENT: L. reuteri DSM 17938/ATCC PTA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation
Status: RECRUITING
Conditions: Femoral Neck Fractures|Internal Fixation
Interventions: DEVICE: three cancellous screws|DEVICE: four cancellous screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of HepaGam B® in Combination With Antiviral Treatment in Hepatitis B Liver Transplant Patients
Status: COMPLETED
Conditions: Hepatitis B|Liver Transplantation
Interventions: BIOLOGICAL: HepaGam B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Feasibility of a Patient-centered Transition Program for Stroke Patients and Their Informal Caregivers, Combining Follow-up by a Case-manager and Access to an Internet Information Platform
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: Follow-up by a case-manager and access to the internet platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: International Care Bundle Evaluation in Cerebral Hemorrhage Research
Status: NOT_YET_RECRUITING
Conditions: Intracerebral Hemorrhage|Intracerebral Haemorrhage|Intraventricular Hemorrhage|Stroke|Cerebrovascular Disease
Interventions: OTHER: Reversal of Oral anticoagulation within 30 minutes|OTHER: Early intensive blood pressure lowering|OTHER: Treatment of pyrexia|OTHER: Hyperglycemia treatment|OTHER: Do-not-resuscitate (DNR) or withdrawal of care|OTHER: Referral to Intensive Care|OTHER: Referral to Neurosurgery|DIAGNOSTIC_TEST: Repeat brain imaging|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.
Status: RECRUITING
Conditions: Pediatric Liver Transplant
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determine Function of Antroquinonol in Combination With SOC in First Line Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Neoplasm
Interventions: DRUG: Antroquinonol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing a Wellbeing Program for Care-partners of Those With SCI
Status: NOT_YET_RECRUITING
Conditions: Internet-Delivered Cognitive Behavioural Therapy|Depression|Anxiety|Spinal Cord Injuries|Caregiver Burnout
Interventions: OTHER: ICBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamins D and K Effects on Vascular Function in Obese Adults.
Status: RECRUITING
Conditions: Obesity|Vitamin D3 Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 + K2-MK7|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of 3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome
Status: COMPLETED
Conditions: Lambert-Eaton Myasthenic Syndrome
Interventions: DRUG: 3,4-diaminopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Talampanel for Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: ALS
Interventions: DRUG: Talampanel|DRUG: Talampanel|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Assess the Safety and Tolerability of BMS-963272 in Obese But Otherwise Healthy Adults
Status: COMPLETED
Conditions: Obese But Otherwise Healthy Participants
Interventions: DRUG: BMS-963272|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KidneYou - Innovative Digital Therapy
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Diabetes|Arterial Hypertension|Chronic Glomerulonephritis|Cystic Kidney Diseases|Polycystic Kidney|Nephronophthisis|Cortical Cystic Disease|Cystic Diseases|Tuberous Sclerosis|Albuminuria|Treatment Adherence|Treatment Adherence and Compliance
Interventions: DEVICE: KidneYou APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feeding With Indirect Calorimetry and Cycling in the Elderly
Status: ACTIVE_NOT_RECRUITING
Conditions: Calorimetry, Indirect|Exercise Therapy|Critical Care|Muscular Atrophy
Interventions: OTHER: Indirect Calorimetry directed feeding.|PROCEDURE: Cycle Ergometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Erythropoietin After Revascularization in Myocardial Infarction (REVIVAL-3)
Status: COMPLETED
Conditions: Myocardial Infarction|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Erythropoietin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Donor Lymphocytes Sensitized by Antigens Expressed by the Host
Status: WITHDRAWN
Conditions: Hematological Malignancy|Neoplasm Metastasis
Interventions: PROCEDURE: DLI sensitized against antigens expressed by the host.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems
Status: COMPLETED
Conditions: Cognitive Impairment|Delirium
Interventions: BEHAVIORAL: e-CHAMP (Enhancing Care for Hospitalized Older Adults with Cognitive Impairment)|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Cognitive Function Study of EVP-6124 Versus Placebo in Subjects With Nicotine Dependence
Status: TERMINATED
Conditions: Nicotine Dependence|Smoking Cessation
Interventions: DRUG: EVP-6124|DRUG: Placebo Capsule|DRUG: NicoDerm Patch (Active)|DRUG: NRT Patch (Placebo)|BEHAVIORAL: Brief Supportive and Behavioral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System
Status: UNKNOWN
Conditions: Single Coronary Vessel Disease
Interventions: DEVICE: Device: Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEBE Project - Healthy Aging Versus Inflamm-aging: the Role of Physical Exercise in Modulating the Biomarkers of Age-associated and Environmentally Determined Chronic Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VivaGel™ in Healthy Young Women
Status: COMPLETED
Conditions: Herpes Simplex II
Interventions: DRUG: 3% w/w SPL7013 Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Pistachios on Muscle Recovery
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Water|DIETARY_SUPPLEMENT: 1.5 oz Pistachios|DIETARY_SUPPLEMENT: 3.0 oz Pistachios
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Traditional Chinese Medicine Formula Liu-Wei-Die-Huang-Wan in the Treatment of Osteoarthritis.
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: TCM OA2|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Episodic Future Thinking and Future Thinking Priming for Smoking Cessation
Status: TERMINATED
Conditions: Tobacco-Related Carcinoma
Interventions: BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|BEHAVIORAL: Behavioral Intervention|OTHER: Informational Intervention|DRUG: Nicotine Replacement|OTHER: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Morphometric, Clinical and Histological Study on One Stage Bone Augmentation Using BoneCeramic (BCP) and Collagen Membranes
Status: COMPLETED
Conditions: Dehiscent Type of Alveolar Bone Defect|One Stage Bone Augmentation
Interventions: DEVICE: Ossix|DEVICE: Biogide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga DOTA-TATE PET/CT in Somatostatin Receptor Positive Tumors
Status: NO_LONGER_AVAILABLE
Conditions: Carcinoid Tumors|Islet Cell (Pancreatic NET)|Other Neuroendocrine Tumors
Interventions: DRUG: 68Ga-DOTA TATE
Study Type: EXPANDED_ACCESS
Clinical trial: Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT
Status: RECRUITING
Conditions: Chronic Pancreatitis|Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Bone marrow-derived mesenchymal stem cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil Affects Cognition and ADHD Symptoms in Adults With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Experimental: Fish Oil|DIETARY_SUPPLEMENT: Comparator: Safflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer|Ototoxicity
Interventions: DRUG: cisplatin|DRUG: sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Blood Flow in Early Glaucoma Patients Before and After Treatment With Dorzolamide
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Dorzolamide 2% drops|DEVICE: HRF and CLBF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Antimicrobials Versus Placebo in Addition to Fecal Transplant Therapy in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Metronidazole|DRUG: Doxycycline|DRUG: Terbinafine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovarian Tissue Cryopreservation in Females Undergoing Procedures That Will Potentially Lead To Loss of Ovarian Function
Status: COMPLETED
Conditions: Cancer|Effects of Chemotherapy|Unspecified Complication of Bone Marrow Transplant|Auto Immune Disease
Interventions: PROCEDURE: Retrieval and Cryopreservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate the Somnotouch Device to Quantify Spontaneous Baroreflex Sensitivity
Status: COMPLETED
Conditions: Healthy|Heart Failure
Interventions: DEVICE: SOMNOtouch device (Somnomedics)|PROCEDURE: Orthostatic test|DEVICE: Finapres Nova device (FMS system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Minocycline HCL Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Crystallization Inhibition Capacity of the Uric Acid in Urine in a Group of Lithiasic Patients After Intake of a Food Supplement
Status: COMPLETED
Conditions: Lithiasis
Interventions: DIETARY_SUPPLEMENT: Lit Control pH Up|DIETARY_SUPPLEMENT: dry cocoa extract
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home
Status: COMPLETED
Conditions: Premature|Low Birth Weight|Mother-Infant Interaction|Gain, Weight|Depression, Post-Partum|Breastfeeding|Feeding, Breast
Interventions: BEHAVIORAL: Kangaroo Baby Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumours
Interventions: DRUG: Ceralasertib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Pharmacodynamics and Pharmacokinetics of Insulin Aspart, BIAsp70, BIAsp50 and Fast-acting Human Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin Aspart, BIAsp 70, BIAsp50, Human Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient
Status: COMPLETED
Conditions: Lumbar Herniated Intervertebral Disc
Interventions: DEVICE: 1,414nm Nd:YAG Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Enriched, Autologous, Activated T-Cells Directed to Tumor in Patients With Relapsed/Refractory Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: tvs-CTL Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Lymphoma, Large B-Cell, Diffuse|Cardiotoxicity|Left Ventricular Dysfunction|Chemotherapy Effect
Interventions: DRUG: Nebivolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Amnion Chorion Membrane in Comparison to Subepithelial Connective Tissue Graft in Gingival Recession Coverage
Status: COMPLETED
Conditions: Gingival Recession
Interventions: BIOLOGICAL: amnion chorion allograft membrane|PROCEDURE: coronally advanced flap with the subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Impact of Volume Targeted Ventilation in the Delivery Room
Status: RECRUITING
Conditions: Prematurity|BPD - Bronchopulmonary Dysplasia|Respiratory Distress Syndrome, Newborn
Interventions: DEVICE: Volume Targeted Ventilation (VTV) using the Philips Respironics NM3 monitor|DEVICE: Tidal Volume Measurement using the Philips Respironics NM3 monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exergaming on Hand Dexterity In Autistic Children
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Exergaming|OTHER: Conventional Dexterity Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Late-onset Pompe Disease
Status: COMPLETED
Conditions: Glycogen Storage Disease Type II|Glycogenosis 2
Interventions: BIOLOGICAL: Myozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HL-085 and Vemurafinib in Metastatic Colorectal Cancer (mCRC)
Status: RECRUITING
Conditions: CRC
Interventions: DRUG: HL-085|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Status: WITHDRAWN
Conditions: Amblyopia|Myopia|Hyperopia|Astigmatism|Cataract|Retinoblastoma|Trachoma|Xerophthalmia|Glaucoma|Retinopathy of Prematurity
Interventions: DEVICE: Spot photoscreener|PROCEDURE: Ophthalmologic evaluation|PROCEDURE: Cyclopleged refraction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Steroids in Occipital Nerve Block for Treatment of Headache
Status: RECRUITING
Conditions: Headache|Occipital Nerve Block
Interventions: DRUG: Bupivacaine|DRUG: Lidocaine|DRUG: Dexamethasone|DRUG: Normal saline|PROCEDURE: Greater/lesser occipital nerve blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: Polysiloxane Gd-Chelates based nanoparticles (AGuIX)|RADIATION: radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Training on Adipose Tissue Metabolism and Insulin Sensitivity in the Menopausal Transition Phase
Status: COMPLETED
Conditions: Menopause|Insulin Resistance|Body Composition, Beneficial
Interventions: BEHAVIORAL: Spinning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serotonin Release in Premotor and Motor PD
Status: RECRUITING
Conditions: Parkinson Disease|Parkinson's|Parkinson's Disease|Neurodegenerative Diseases|Neurodegeneration|Positron Emission Tomography
Interventions: OTHER: Positron Emission Tomography (PET) scan using CIMBI-36 tracer|OTHER: Magnetic Resonance Imaging (MRI) Scan|OTHER: Positron Emission Tomography (PET) scan using DASB tracer|OTHER: FP-CIT Single-photon Emission Computed Tomography (SPECT) scan|OTHER: Lumbar puncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of an Educational Intervention Based on Self-help for Sleep Hygiene Promotion on Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia|Behavioral Intervention
Interventions: BEHAVIORAL: self help sleep hygiene intervention application|OTHER: patients education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Electrical Phrenic Nerve Stimulation and Transcutaneous Electrical Diaphragmatic Stimulation
Status: RECRUITING
Conditions: Diaphragm
Interventions: OTHER: Transcutaneous electrical phrenic nerve stimulation (TEPNS)|OTHER: Transcutaneous electrical diaphragm stimulation (TEDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HSD-016
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: HSD-016|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAF
Status: RECRUITING
Conditions: Drug Refractory Paroxysmal Atrial Fibrillation
Interventions: DEVICE: THERMOCOOL STSF Bi- Directional Navigation Catheter|DEVICE: TRUPULSE Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Opioid Avoidance Protocol for ACL Reconstruction
Status: RECRUITING
Conditions: ACL Tear|Post Operative Pain
Interventions: DEVICE: Iovera|DRUG: Celecoxib|DRUG: Acetaminophen|DRUG: Oxycodone|DRUG: Tramadol|DRUG: Bupivacaine Hydrochloride|DRUG: Acetaminophen 500Mg Cap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acetyl-L-Carnitine Reduces Perceived Work Stress and Improves Work Ability and Work Performance in Hepatic Encephalopathy
Status: COMPLETED
Conditions: Work Stress|Work Ability|Work Performance
Interventions: DRUG: Acetyl-L-carnitine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Gleevec, RAD001, and Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress
Status: COMPLETED
Conditions: Alcohol Use Disorder|Stress Disorders, Post-Traumatic|Anxiety Disorders|Substance Use Disorders
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transvaginal vs Transabdominal Ultrasound Guided Embryo Transfer
Status: UNKNOWN
Conditions: In Vitro Fertilization
Interventions: PROCEDURE: transabdominal ultrasound|PROCEDURE: transvaginal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ridaforolimus and Vorinostat in Treating Patients With Advanced Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ridaforolimus|DRUG: vorinostat|PROCEDURE: biopsy|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROmotion of COvid-19 VA(X)Ccination in the Emergency Department - PROCOVAXED
Status: TERMINATED
Conditions: Covid-19 Vaccine|Vaccine Hesitancy
Interventions: OTHER: Covid-19 vaccine education materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized Phase II Trial of Salvage Radiotherapy for Prostate Cancer In 4 Weeks v. 2 Weeks
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: 5 days Radiation Therapy (32.5 Gy in 5 fractions)|RADIATION: 20 days Radiation therapy (55 Gy in 20 fractions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hi-tACS on Cognitive Function in Patients With Schizophrenia: a Pilot Study
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: high-frequency transcranial alternating current stimulation|DEVICE: sham high-frequency transcranial alternating current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: TAVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Mindfulness Intervention: Distress Tolerance Dose Manipulation
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress|Emotional Disorder
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)-normal version|BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)-increase distress tolerance|BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)-decrease distress tolerance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Urinary Kallikrein to Enhance Collateral Circulation in Symptomatic Intracranial Atherosclerosis
Status: WITHDRAWN
Conditions: Intracranial Arteriosclerosis|Collateral Circulation|Anterior Cerebral Circulation Infarction
Interventions: DRUG: Urinary Kallikrein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Pneumoperitoneum Timing on Intracranial Pressure in Laparoscopy
Status: COMPLETED
Conditions: Intracranial Pressure Increase|Pneumoperitoneum
Interventions: PROCEDURE: Pneumoperitoneum Timing (Before Positioning)|PROCEDURE: Pneumoperitoneum Timing (After Positioning)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Drug Interaction of DWP16001 and DWC202010 After Oral Administration in Healthy Adults
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: DWP16001|DRUG: DWP202010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With Expanded Programme on Immunization Vaccines
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: Concomitant administration of EV71vaccine with EPI vaccines|BIOLOGICAL: Single injection of EPI vaccine|BIOLOGICAL: EV71 Vaccine only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Dexmedetomidine on the Evoked Potentials During Spine Surgery
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: PRT064445/Apixaban|COMBINATION_PRODUCT: Placebo/Apixaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Vitamin E and Hydrogen-Rich Water on Radiation Therapy-Induced Adverse In Patients With Rectal Cancer
Status: UNKNOWN
Conditions: Radiation-induced Injuries in Patients With Rectal Cancer
Interventions: DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Hydrogen rich water|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During Pregnancy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine/Tenofovir Disoproxil Fumarate|DRUG: Lamivudine/Zidovudine|DRUG: Lopinavir/Ritonavir|DRUG: single dose Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Tacrolimus Dose in Association With Mycophenolate Mofetil After Liver Transplantation
Status: TERMINATED
Conditions: Evidence of Liver Transplantation
Interventions: DRUG: Mycophenolate mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HILT for Meralgia Paresthetica: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Meralgia Paresthetica|Lateral Femoral Cutaneous Nerve Entrapment
Interventions: DEVICE: High-Intensity Laser Therapy (HILT)|DEVICE: Sham High-Intensity Laser Therapy (Sham HILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer.
Status: WITHDRAWN
Conditions: Rectum Cancer|Quality of Life|Faecal Incontinence|Low Anterior Resection Syndrome
Interventions: PROCEDURE: Low Anterior Resection for Rectum Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage, Aneurysmal
Interventions: DRUG: EG-1962 (nimodipine microparticles)|DRUG: Enteral Nimodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: Tianzhi granule and placebo identified to donepezil|DRUG: Donepezil and placebo identified to Tianzhi granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of Combination Azithromycin and Hydroxychloroquine vs. Hydroxychloroquine Alone for the Treatment of Confirmed COVID-19
Status: TERMINATED
Conditions: SARS-CoV-2|COVID-19
Interventions: COMBINATION_PRODUCT: Hydroxychloroquine Sulfate + Azithromycin|DRUG: Hydroxychloroquine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening to Predict Weight Loss in Patients With Cancer
Status: UNKNOWN
Conditions: Cachexia|Gastrointestinal Cancer|Hematopoietic/Lymphoid Cancer|Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: laboratory biomarker analysis|OTHER: physiologic testing|OTHER: questionnaire administration|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RADIANT: CD101 vs Standard of Care in Subjects With Acute Vaginal Yeast Infections
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal|Mycoses|Yeast Infection|Moniliasis, Vulvovaginal|Vaginitis, Monilial
Interventions: DRUG: CD101 Vaginal Gel (3%)|DRUG: CD101 External gel (1%)|DRUG: CD101 Vaginal Ointment (6%)|DRUG: CD101 External ointment (1%)|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Test the Efficacy and Safety of Adapalene, 0.1%
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene lotion 0.1%|DRUG: Adapalene Lotion Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opiate-Induced Tolerance & Hyperalgesia in Pain Patients
Status: COMPLETED
Conditions: Chronic Low Back Pain|Opioid-induced Hyperalgesia
Interventions: DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes
Status: COMPLETED
Conditions: Chronic Foot Ulcers
Interventions: DRUG: Placebo|DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT