pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Testing the Feasibility of a Sports-based Mental Health Promotion Intervention for Adolescents in Nepal
Status: RECRUITING
Conditions: Mental Health Wellness
Interventions: OTHER: sports based mental health promotion program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Personalized Diet Study to Reduce Glycemic Exposure
Status: COMPLETED
Conditions: Pre-diabetes|Overweight and Obesity
Interventions: BEHAVIORAL: mHealth|BEHAVIORAL: Personalized mHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cooking Matters for Diabetes - A 6-Week Program for Practical Application of Diabetes Self-Management Education
Status: COMPLETED
Conditions: Diabetes Mellitus|Type 1 Diabetes|Type 2 Diabetes
Interventions: BEHAVIORAL: Cooking Matters for Diabetes|OTHER: Usual Diabetes Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of Different Doses of BI 1026706 in Patients With Postoperative Dental Pain
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Placebo to BI 1026706 solution|DRUG: BI 1026706|DRUG: Placebo to BI 1026706 tablet|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Global Prospective Observational Registry of Patients With Pompe Disease
Status: RECRUITING
Conditions: Pompe Disease
Interventions: BIOLOGICAL: Cipaglucosidase alfa|DRUG: Miglustat|BIOLOGICAL: Alglucosidase alfa or Avalglucosidase alfa|OTHER: Untreated
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of KQ-791 in Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: KQ-791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Depressive Symptoms
Interventions: DRUG: Esketamine hydrochloride|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Versus Intraperitoneal Instillation of Ondansetron for Decreasing Incidence of Nausea and Vomiting After Laparoscopic Gynecological Surgeries.
Status: UNKNOWN
Conditions: Prevention
Interventions: DRUG: Intraperitoneal instillation of ondansetron and bupivacaine|DRUG: Intravenous ondansetron and intraperitoneal instillation of bupivacaine|DRUG: Intraperitoneal instillation of bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Chronic Graft Versus Host Disease|Hematologic and Lymphocytic Disorder|Steroid Refractory Graft Versus Host Disease
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|OTHER: Electronic Health Record Review|PROCEDURE: Leukapheresis|PROCEDURE: Lumbar Puncture|PROCEDURE: Magnetic Resonance Imaging|OTHER: Quality-of-Life Assessment|BIOLOGICAL: Tafasitamab|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Portable Spirometer in Pediatric Patients With Cystic Fibrosis at the Nancy CHRU: Feasibility Study
Status: UNKNOWN
Conditions: Cystic Fibrosis in Children
Interventions: DEVICE: Spirobank Smart
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post-Market Clinical Follow-Up of STRATAFIX™ Spiral PDS™ PLUS
Status: COMPLETED
Conditions: Bariatric - Sleeve Gastrectomy Staple Line Reinforcement|Gynecology - Vaginal Cuff Closure
Interventions: DEVICE: Robotic Suturing of gastric sleeve oversew and vaginal cuff closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Safety and Feasibility Study for the Treatment of Tourette Syndrome
Status: UNKNOWN
Conditions: Tourette's Syndrome|Obsessive Compulsive Disorder
Interventions: DEVICE: HBDL-coil Repetitive Deep Transcranial magnetic stimulation (rdTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axillary Staging in Node Positive Breast Cancer Patients Receiving PST. SNB vs PET/MRI
Status: RECRUITING
Conditions: Breast Cancer Female|Node-positive Breast Cancer|Sentinel Lymph Node
Interventions: DIAGNOSTIC_TEST: PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Trial of a Synbiotic in HIV+ Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: DIETARY_SUPPLEMENT: Synbiotic 2000|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Dose Two-periods Crossover Bioequivalence Study of Darifenacin Tablets in Healthy Volunteers.
Status: UNKNOWN
Conditions: Bioequivalency
Interventions: DRUG: Darifenacin|DRUG: Darifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Intratumoral PV701 in Treating Patients With Advanced or Recurrent Unresectable Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Salivary Gland Squamous Cell Carcinoma|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Salivary Gland Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Interventions: BIOLOGICAL: PV701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Negative Symptoms in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Pessary Treatment for Prevention of s PTB in Twin Pregnancies on Children's Long-Term Outcome
Status: NOT_YET_RECRUITING
Conditions: Preterm Birth|Premature Birth
Interventions: DEVICE: Cervical Pessary-Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oxytocin Modulates Eye Gaze Behavior During Social Processing
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: intranasal oxytocin|DRUG: intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Energy Deficit Syndrome in Female Athletes. Molecular Mechanisms Associated With Malnutrition.
Status: COMPLETED
Conditions: Female Athlete Triad|Energy Deficit Syndrome|Mediterranean Diet|Red Fruits|Antioxidative Stress|Nutritional Disorder|Sports Physical Therapy
Interventions: OTHER: Free use of the virtual platform.|OTHER: Personalized nutritional planning based on the Mediterranean diet + physical exercise + use of mobile application.|OTHER: Personalized nutritional planning with an extra intake of berries + physical exercise + use of mobile application.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF)
Status: RECRUITING
Conditions: Acute Heart Failure
Interventions: DRUG: Dexamethasone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: OTHER: Didgeridoo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bone-anchored Protraction on Maxillary Growth in the Young Child
Status: UNKNOWN
Conditions: Maxillary Hypoplasia|Malocclusion, Angle Class III
Interventions: DEVICE: Face mask|DEVICE: orthodontic bone anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial
Status: UNKNOWN
Conditions: Chronic Periodontitis|End Stage Renal Disease
Interventions: OTHER: Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Isoflavone Combined With Astaxanthin on Skin Aging
Status: COMPLETED
Conditions: Ageing|Photo-aging
Interventions: DIETARY_SUPPLEMENT: Isoflavone|DIETARY_SUPPLEMENT: Astaxanthin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPI-613 and Hydroxychloroquine for Patients With High Risk Myelodysplastic Syndrome
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes|Progressive Disease
Interventions: DRUG: CPI-613|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes
Status: RECRUITING
Conditions: Sexually Transmitted Infection|HIV/AIDS|Cost-effectiveness|Birth Outcomes|Vaginal Microbiome|Neisseria Gonorrhoeae|Chlamydia Trachomatis|Trichomonas Vaginalis|Antenatal Care|Pregnancy
Interventions: DIAGNOSTIC_TEST: First antenatal care + test-of-cure|DIAGNOSTIC_TEST: First antenatal care + week 30-34 gestation (no test-of-cure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL
Status: RECRUITING
Conditions: PTCL|CTCL
Interventions: DRUG: Pembrolizumab|DRUG: Pralatrexate|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Characteristics of DKF-313
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia|Healthy
Interventions: DRUG: DKF-313|DRUG: AVODART|DRUG: CIALIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of RANKL/OPG Levels in Gingival Crevicular Fluid at 1st and 3rd Months of Activation of NaOCl With Er,Cr YSSG Laser in Root Canal Treatment
Status: UNKNOWN
Conditions: Periapical Diseases
Interventions: DEVICE: Er,Cr:YSSG laser|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sour Cherry Anthocyanins on Healthy Human Saliva
Status: ENROLLING_BY_INVITATION
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Pelleted sour cherry (anthocyanin) containing chewing gum usage.|DIETARY_SUPPLEMENT: Pelleted chewing gum for stimulated saliva sampling.|PROCEDURE: Scaling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A New Membrane Obturator Prothesis Concept for Soft Palate Defects
Status: COMPLETED
Conditions: Mouth Neoplasms|Velopharyngeal Insufficiency|Speech Disorders|Deglutition Disorders
Interventions: DEVICE: Suersen and membraneous obturators evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Invitro and ex Vivo Lens Metrology With Daily Wear Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Air Optix Aqua|DEVICE: Biofinity|DEVICE: Proclear|DEVICE: Acuvue Oasys|DEVICE: Acuvue 2|DEVICE: Purevision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transurethral En Bloc Versus Standard Resection of Bladder Tumour
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: Bipolar transurethral standard resection|DEVICE: Bipolar transurethral en bloc resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Chronic Supplementation of L-arginine in the Muscular Performance
Status: TERMINATED
Conditions: Muscular Fatigue
Interventions: DRUG: L-arginine aspartate (Targifor)|DRUG: Placebo L-arginine aspartate (Targifor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Relationship of Neuropathic Pain With Incontinence, Disability and Life Quality in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis|Disabilities Multiple|Quality of Life|Incontinence, Urinary|Incontinence Bowel|Neuropathic Pain
Interventions: OTHER: Neuropathic Pain
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tafluprost Preservative Free Switch Study
Status: COMPLETED
Conditions: Glaucoma|Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: preservative free tafluprost 0.0015%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Demonstrate the Safety and Effectiveness of the MiStent II for the Revascularization of Coronary Arteries.
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: MiStent II coronary artery stent|DEVICE: Xience or Promus coronary artery stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial With Influenza A/H1N1 Vaccines
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: split-virion, adjuvanted H1N1 vaccine of 7.5 μg per dose|BIOLOGICAL: split-virion, adjuvanted H1N1 vaccine of 15 μg per dose|BIOLOGICAL: split-virion, non-adjuvanted H1N1 vaccine of 15 μg per dose|BIOLOGICAL: split-virion, non-adjuvanted H1N1 vaccine of 30 μg per dose|BIOLOGICAL: whole-virion, adjuvanted H1N1 vaccine of 5 μg per dose|BIOLOGICAL: whole-virion, adjuvanted H1N1 vaccine of 10 μg per dose|BIOLOGICAL: placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in Patients With Colorectal Cancer (FOLFIRINOX 3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRINOX Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: IMM01|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of HOsPitalised Inpatients for Hepatitis C (TOPIC): Therapeutic Intervention Enhancing Care Linkage in People Who Inject Drugs
Status: RECRUITING
Conditions: Hepatitis C|Liver Inflammation|Liver Cirrhoses
Interventions: DRUG: Glecaprevir/Pibrentasvir 100 MG-40 MG Oral Tablet|DRUG: Sofosbuvir 400 MG + Glecaprevir/Pibrentasvir 100 MG-40 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery
Status: TERMINATED
Conditions: Cervical Spondylosis|Lumbar Spondylosis
Interventions: DRUG: Ibuprofen|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Electrical Spinal Cord Stimulation To Restore Upper Extremity Function in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: COMBINATION_PRODUCT: Transcutaneous electrical spinal cord stimulation + therapy|OTHER: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subjects With Schizophrenia Taking SEP-363856 or and Prior Antipsychotic (PA) Standard
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856|DRUG: Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Smoking Treatment Programs for Lighter Smokers - 1
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: nicotine transdermal system|DRUG: bupropion|BEHAVIORAL: Medication Management|BEHAVIORAL: Mayo Counseling|DRUG: placebo patch|DRUG: placebo bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using FoodFlip© to Improve Food Choices Among Post-secondary Students
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Diet
Interventions: DEVICE: FoodFlip© App with no nutrition symbol|DEVICE: FoodFlip© App with 'high-in' nutrition symbol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Recovery Support for Bladder Cancer Patients and Caregivers
Status: RECRUITING
Conditions: Bladder Cancer|Patient Engagement|Patient Empowerment|Ileal Conduit
Interventions: BEHAVIORAL: Cancer Resource Information Support (CRIS)|BEHAVIORAL: Usual Care Enhanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reaching Out to the UNdiagnosed People Infected With Blood Borne Viral Infections
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis c|Human Immunodeficiency Virus
Interventions: OTHER: finger prick screening for BBV infections and questionnaires by outreaching methodology
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Correlation Between NAFLD, Epicardial Adipose Tissue and Vascular Inflammation Measured by Positron Emission Tomography (PET) With 18F-fluoro-deoxyglucose (FDG)
Status: COMPLETED
Conditions: Atherosclerosis|Non-alcoholic Fatty Liver Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Echocardiographic Evaluation of the Change on Pulmonary Blood Flow and Cardiac Function During One-lung Ventilation
Status: COMPLETED
Conditions: Video-assisted Thoracic Surgery
Interventions: PROCEDURE: transesophageal echocardiography(TEE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Emergency Laparoscopic Cholecystectomy With Low Pressure Pneumo-peritoneum in Cardiopulmonary Risk Patients: Fundus First Cholecystectomy VS Calot First Cholecystectomy .
Status: COMPLETED
Conditions: Laparoscopy|Biliary Disease
Interventions: PROCEDURE: start with fundus|PROCEDURE: calot first dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp
Status: RECRUITING
Conditions: Infertility|Endometriosis
Interventions: DRUG: Elagolix 200 MG|OTHER: Placebo or SOC IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction of Glazed IPS Empress CAD Versus Glazed Celtra Duo Ceramic Laminate Veneers
Status: UNKNOWN
Conditions: Tooth Discoloration|Tooth Fractures
Interventions: OTHER: glazed Celtra Duo|OTHER: IPS Empress CAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PCP Use of a Gene Expression Test (Corus CAD or ASGES) in Coronary Artery Disease Diagnosis
Status: COMPLETED
Conditions: Chest Pain|Cardiovascular Diseases|Angina Pectoris|Coronary Artery Disease|CAD|CVD|CHD|Coronary Heart Disease
Interventions: DIAGNOSTIC_TEST: Corus CAD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Disease, Chronic|Peritoneal Dialysis Catheter-Associated Peritonitis|Peritoneal Dialysis Catheter Exit Site Infection|Peritoneal Dialysis Catheter Tunnel Infection
Interventions: BEHAVIORAL: TEACH-PD Training Curriculum|BEHAVIORAL: Current standard PD training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EUREKA Italy - Evaluation of Real-life Use of KLOX BioPhotonic System in Chronic Wounds Management
Status: COMPLETED
Conditions: Venous Leg Ulcer|Diabetic Foot Ulcer|Pressure Ulcer
Interventions: DEVICE: KLOX LumiHeal BioPhotonic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise for Swallowing Problems After Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident|Deglutition Disorders
Interventions: DEVICE: lingual press|BEHAVIORAL: effortful swallowing|BEHAVIORAL: natural swallowing|BEHAVIORAL: non-oral sham (control) exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Human Infection With Neisseria Gonorrhoeae
Status: COMPLETED
Conditions: Gonococcal Infection
Interventions: DRUG: Cefixime|DRUG: Ceftriaxone|DRUG: Ciprofloxacin|BIOLOGICAL: Neisseria gonorrhoeae strain FA1090 A26|BIOLOGICAL: Neisseria gonorrhoeae strain FA7537
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD
Status: RECRUITING
Conditions: Opioid Use Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged exposure therapy|BEHAVIORAL: Financial incentives|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Choline Dehydrogenase and Sperm Function: Effects of Betaine
Status: COMPLETED
Conditions: Men Carrying 2 Minor Alleles for Choline Dehydrogenase rs12676|Male Infertility
Interventions: DRUG: Betaine supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Cycloergometer in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Fatigue|Leukemia|Lymphoma|Multiple Myeloma|Hematopoietic Stem Cell Transplantation
Interventions: OTHER: Aerobic training with cycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Op Lidocaine Patch
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Lidoderm 5 % Topical Patch|OTHER: Sham Topical Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Dietary Fatty Acids to Lower Metabolic Risk Factors Among Canadians
Status: TERMINATED
Conditions: Postprandial Lipaemia
Interventions: DIETARY_SUPPLEMENT: Butter and Vegetable oils from soy, flaxseed, high oleic safflower and canola|DIETARY_SUPPLEMENT: In this study subjects will consume test meals containing vegetable oils (soy, flaxseed, high oleic safflower and canola) and butter|DIETARY_SUPPLEMENT: In this study subjects will consume test meals containing vegetable oils (soy, flaxseed, high oleic safflower and canola) and butter|DIETARY_SUPPLEMENT: In this study subjects will consume test meals containing vegetable oils (soy, flaxseed, high oleic safflower and canola) and butter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Outcomes of Post-placental Insertion of Cupper T380A and Multiload 375 Contraceptive Devices During Cesarean Section
Status: ACTIVE_NOT_RECRUITING
Conditions: IUD (Intrauterine Device) Malposition|IUD; Complications, Infection or Inflammation
Interventions: DEVICE: CU T380A IUD|DEVICE: multiload 375 IUD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physical Activity: Feasibility Study
Status: RECRUITING
Conditions: Obesity|Physical Activity|Self-efficacy|Online Intervention|Accelerometers
Interventions: BEHAVIORAL: Physical Activity Self-efficacy (PAS) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease on Dialysis
Interventions: DRUG: Vitamin K1|DRUG: Vitamin k2|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of Psychosocial Treatments for Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: Capnometry Assisted Respiratory Training (CART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis, Chronic Progressive
Interventions: DRUG: lipoic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing SEP-363856 in Male and Female Volunteers With High or Low Schizotype Characteristics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856|DRUG: Amisulpride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tadalafil in Becker Muscular Dystrophy
Status: COMPLETED
Conditions: Becker Muscular Dystrophy
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Dose Aprepitant for Patients Receiving Carboplatin
Status: TERMINATED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Aprepitant 125 mg|DRUG: Fosaprepitant 115 MG|DRUG: Dexamethasone|DRUG: Ondansetron 16 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DRUG: Placebo for Sitagliptin 25 mg|DRUG: Placebo for Sitagliptin 50 mg|DRUG: Sitagliptin 25 mg|DRUG: Sitagliptin 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
Status: RECRUITING
Conditions: Optic Neuritis
Interventions: DRUG: Clemastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of Cultured Cornea Stem Cells in Patients Suffering From Corneal Stem Cell Insufficiency
Status: TERMINATED
Conditions: Unilateral Limbal Stem Cell Insufficiency
Interventions: PROCEDURE: Transplant of cultured limbal stem cells on cornea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PNFand Perturbations Based Exercises on Balance Training in Elder Population
Status: COMPLETED
Conditions: Balance; Distorted
Interventions: OTHER: proprioceptive neuromuscular facilitation|OTHER: pertubation based balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wiser Choices in Osteoporosis Choice II: A Decision Aid for Patients and Clinicians
Status: COMPLETED
Conditions: Osteoporosis|Osteopenia|Fragility Fractures
Interventions: BEHAVIORAL: FRAX + Decision Aid|BEHAVIORAL: FRAX estimated fracture risk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of OnabotulinumtoxinA for Depression in Parkinson Disease
Status: TERMINATED
Conditions: Parkinson Disease|Depression
Interventions: BIOLOGICAL: OnabotulinumtoxinA|BIOLOGICAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)-China Extension Study
Status: WITHDRAWN
Conditions: Esophageal Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Placebo|DRUG: Cisplatin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2|Glucose, High Blood|Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions: DRUG: Diazoxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-Human Assessment of Safety, Biodistribution and Pharmacokinetics of 18F-Fluoro-1-Naphthol (18F-4FN) for PET Imaging
Status: RECRUITING
Conditions: Endocrine Neoplasia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications
Status: COMPLETED
Conditions: Covid19|Coronavirus Infection
Interventions: DRUG: Fisetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized or Precision Medicine in the Dietary Approach to Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: OTHER: MedDiet Arm|OTHER: KetoDiet Arm|OTHER: IF Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema
Status: TERMINATED
Conditions: Angioedema Caused by Angiotensin-Converting-Enzyme Inhibitor
Interventions: BIOLOGICAL: High ACE Activity Fresh Frozen Plasma|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Field Study of Anthim (Obiltoxaximab) in Subjects Exposed to B. Anthracis
Status: NOT_YET_RECRUITING
Conditions: Infection, Bacterial|Anthrax
Interventions: OTHER: Collection of samples|BIOLOGICAL: Obiltoxaximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Epstein-Barr Virus Infection
Interventions: BIOLOGICAL: mRNA-1195.1|BIOLOGICAL: mRNA-1195.2|BIOLOGICAL: mRNA-1189|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Transcutaneous Electrical Nerve Stimulation and Cupping Therapy in The Treatment of Tennis Elbow: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: OTHER: conventional therapy|OTHER: cupping therapy|DEVICE: TENS|OTHER: TENS and cupping therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Palbociclib 125mg|DRUG: Aromatase Inhibitors|DRUG: Fulvestrant Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Grape Consumption on Brain Metabolism and Cognitive Function
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Grape Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Clinical Trial to Evaluate a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults
Status: COMPLETED
Conditions: Staphylococcus Aureus Infection
Interventions: BIOLOGICAL: Low dosage of Staphylococcus aureus vaccine (15µg/0.6ml)|BIOLOGICAL: Middle dosage of Staphylococcus aureus vaccine (30µg/0.6ml)|BIOLOGICAL: High dosage of Staphylococcus aureus vaccine (60µg/0.6ml)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Quantitative MRI in Assessing Disease in Patients With Brain Tumors
Status: TERMINATED
Conditions: Tumors Metastatic to Brain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: chemical exchange saturation transfer magnetic resonance imaging|PROCEDURE: dynamic contrast-enhanced magnetic resonance imaging|PROCEDURE: dynamic susceptibility contrast-enhanced magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Distress Reduction Intervention for Patients With BCR-ABL-Negative MPNs or CML on Tyrosine Kinase Inhibitors
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm|Chronic Phase Chronic Myelogenous Leukemia|Chronic Myeloid Leukemia
Interventions: BEHAVIORAL: Online Mindfulness Meditation|OTHER: Internet-Based Webinars
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaccine Therapy in Treating Patients With Recurrent Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer
Interventions: BIOLOGICAL: PSA:154-163(155L) peptide vaccine|BIOLOGICAL: incomplete Freund's adjuvant|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telatinib in Combination With Capecitabine/ Oxaliplatin in 1st Line Gastric or GEJ Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Telatinib|DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Detection of Dysplasia in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: PROCEDURE: HRME+CVC|PROCEDURE: conventional endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Amantadine to Speed Awakening After Cardiac Arrest
Status: COMPLETED
Conditions: Coma|Heart Arrest|Anoxia
Interventions: DRUG: Amantadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Urethral Catheter Necessary After Ureteroscopy and DJ Stent Placement?
Status: COMPLETED
Conditions: Complications; Urethral Catheter|Ureteral Catheterization|Ureteroscopy|Lower Urinary Tract Symptoms|Flank Pain
Interventions: PROCEDURE: urethral catheter placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning on Brain Injury in Carotid Endarterectomy
Status: UNKNOWN
Conditions: Brain Injuries|Remote Ischemic Preconditioning
Interventions: PROCEDURE: Remote Ischemic Preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single-Center, Double-Blind, Randomized , Parallel Study Comparing Onset of Action, Efficacy & Safety of a Single-Dose of Fexofenadine HCl 180 mg vs Montelukast Na 10 mg & Placebo in Treating Seasonal Allergic Rhinitis Subjects in an Allergen Exposure Unit
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Fexofenadine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of Paracetamol-caffeine and Laser Irradiation on Controlling Pain and Discomfort During Orthodontic Treatment
Status: COMPLETED
Conditions: Pain and Discomfort|Orthodontic Appliance Complication
Interventions: RADIATION: low-level laser therapy|DRUG: Panadol-extra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tadalafil Effects in Left Ventricle Diastolic Dysfunction in Resistant Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: sugar pill|DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CArdiac cT in the Treatment of Acute CHest Pain 2 - Myocardial CT Perfusion
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: CTA+CTP guided treatment strategy|PROCEDURE: CTA guided treatment strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: UMULINE NPH|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of Adding Cureety TechCare Telemonitoring to Usual Care During Injectable Anticancer Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Patients Initiating Injectable Anticancer
Interventions: OTHER: Cureety telemonitoring|OTHER: OPTIMA or equivalent programs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery
Status: COMPLETED
Conditions: Bradycardia
Interventions: DRUG: IM atropine|DRUG: IV atropine|DRUG: Atropine mixed with second dose succinylcholine|DRUG: IM normal saline|DRUG: IV normal saline|DRUG: Normal saline mixed with second dose succinylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ruxolitinib in Thrombocythemia and Polycythemia Vera
Status: RECRUITING
Conditions: Essential Thrombocythemia|Polycythemia Vera
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appropriate Complmentary Feeding Strategies in Infants
Status: COMPLETED
Conditions: Anemia
Interventions: BEHAVIORAL: Nutritionl Education|DIETARY_SUPPLEMENT: Oral Iron Supplementation along with Nturition Eductaion|DIETARY_SUPPLEMENT: Multiple micronutrient fortification plus Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Repetitive Peripheral Magnetic Stimulation in Patients With Achilles Tendinopathy
Status: UNKNOWN
Conditions: Achilles Tendinopathy
Interventions: DEVICE: Repetitive pulsed magnetic stimulation|PROCEDURE: Eccentric Calf Muscle Training for Achilles Tendinopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega 3 FA Supplements as Augmentation in the Treatment of Depression
Status: TERMINATED
Conditions: Major Depression|Cancer|Diabetes|Cardiovascular Diseases
Interventions: DRUG: Desvenlafaxine|DIETARY_SUPPLEMENT: Omega 3 Fatty acids|DRUG: Placebo (for Omega 3 fatty acid supplement)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT