pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of MET vs Mobilization in Management of Post-partum Backache in Females (NVD) and Cesarean Section Delivery
Status: RECRUITING
Conditions: Cesarean Section Complications
Interventions: DIAGNOSTIC_TEST: Mobilization|DIAGNOSTIC_TEST: Muscle Energy Technique (MET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Investigation on the Effects of Bayberry Juice Treatment in Adult Subjects With Features of Fatty Liver Disease
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Chinese bayberry juice|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of SQ109 on QTc Interval in Healthy Subjects
Status: WITHDRAWN
Conditions: Tuberculosis
Interventions: DRUG: SQ109|OTHER: SQ109 Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Subject-driven Titration of Biphasic Insulin Aspart (BIAsp) 30 Twice Daily Versus Investigator-driven Titration of BIAsp 30 Twice Daily Both in Combination With Oral Antidiabetic Drugs in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart 30
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance
Status: RECRUITING
Conditions: COVID-19|Myocarditis
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance, Blood Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Tolerability of Testogel/Nebido in Combination With Exercise and Diet in Hypogonadal Male Patients
Status: COMPLETED
Conditions: Hypogonadism
Interventions: DRUG: Testosterone Undeconate (Nebido-R, BAY86-5037)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceptability of Fortified Bouillon Cubes in Northern Ghana
Status: COMPLETED
Conditions: Food, Fortified|Dietary Habits|Child Development
Interventions: DIETARY_SUPPLEMENT: Upper-level multiple micronutrient-fortified bouillon cube|DIETARY_SUPPLEMENT: Lower-level multiple micronutrient-fortified bouillon cube|DIETARY_SUPPLEMENT: Iodine-fortified bouillon cube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation
Status: TERMINATED
Conditions: Cerebral Cavernous Malformations
Interventions: DRUG: Propranolol|GENETIC: DNA and RNA Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The BEST Trial: Biomarkers for Evaluating Spine Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: Enhanced Self-Care (ESC)|BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Evidence-Based Exercise and Manual Therapy (EBEM)|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Immunotherapy With Chemotherapy in the Treatment of Elderly Patients With Advanced NSCLC (MILES-5)
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Chemotherapy|DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Shear Wave Elastography, Transvaginal Ultrasound and Pelvic MRI in the Diagnosis of Adenomyosis
Status: COMPLETED
Conditions: Adenomyosis|Elastography|Transvaginal Ultrasound|Fibroid Uterus
Interventions: DEVICE: Shear wave elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Apomorphine Effect on Nociceptive Perception in Parkinson's: a Clinical and Imaging Study
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: apomorphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-surgical Interventions for Infertility in Endometriosis
Status: COMPLETED
Conditions: Endometriosis|Infertility, Female
Interventions: DRUG: Cabergoline plus timed intercourse|DRUG: Dydrogesterone plus timed intercourse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-market Prospective Clinical Study of Nagor Perle Mammary Implants
Status: NOT_YET_RECRUITING
Conditions: Breast Reconstruction|Breast Reconstruction Following Mastectomy|Breast Revision|Breast Augmentation|Breast Reconstruction With Silicone Implants|Breast Reconstruction After Mastectomy|Breast Reconstruction Surgery|Breast Implants
Interventions: DEVICE: PERLE Sterile Smooth Opaque gel filled mammary implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Symphion® System In-Office Study
Status: COMPLETED
Conditions: Uterine Leiomyomas|Endometrial Polyps
Interventions: DEVICE: Symphion® Bipolar Hysteroscopic Tissue Resection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study With VY-HTT01, in Adults With Early Manifesting Huntington's Disease
Status: WITHDRAWN
Conditions: Huntington Disease
Interventions: GENETIC: Intraparenchymal rAAV1 - (mi)RNA HTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Leptin Administration After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Overweight
Interventions: DRUG: Leptin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost Efficacy Evaluation of Robot Assisted Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Robotic-Assisted Radical Prostatectomy|PROCEDURE: Laparoscopic Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Intervention on Prevention of Postoperative Delirium
Status: UNKNOWN
Conditions: Delirium|Eras
Interventions: BEHAVIORAL: Evaluation|BEHAVIORAL: nursing care|BEHAVIORAL: rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of tDCS for the Treatment of Functional Dyspepsia
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DEVICE: anodal tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pap Smear Collection With the Papette Brush
Status: COMPLETED
Conditions: Cervical Cancer Screening
Interventions: DIAGNOSTIC_TEST: Papette brush collection|DIAGNOSTIC_TEST: Spatula/cytology brush collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of a Neural Mobilization Intervention Applied to Older Adults With Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain|Chronic Pain|Chronic Musculoskeletal Disease|Older Adults
Interventions: OTHER: Physical Exercise Program|OTHER: Neural Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RETRO (REduction of Therapy in RA Patients in Ongoing Remission)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Control group|OTHER: Reduction group 1|OTHER: Reduction group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Glycine on Atherosclerosis and Metabolic Syndrome-related Parameters.
Status: UNKNOWN
Conditions: Metabolic Syndrome|Dyslipidemias|Diabetes Mellitus|Obesity|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Safety, Tolerability, Biological Effects and Preliminary Pharmacokinetics of Increasing Doses of BIIL 284 BS in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 BS - rising dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
Status: COMPLETED
Conditions: HIV Associated Neurocognitive Disorder
Interventions: DRUG: Fluconazole|DRUG: Paroxetine|DRUG: Paroxetine and Fluconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Effect of Prasugrel vs. Ticagrelor in Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Coronary Artery Disease
Interventions: DRUG: Prasugrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SA58 Nasal Spray in Close Contact With COVID-19 People
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: SA58 Nasal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavior Therapy (CBT) and Mirror Training for Phantom Limb Pain
Status: COMPLETED
Conditions: Phantom Limb
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy and Mirror Retraining|BEHAVIORAL: Supportive therapy|BEHAVIORAL: Mirror retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Naproksen Sodium+Codein and Paracetamol+Codein on Postoperative Pain on Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain, PCA Contramal Consumption
Interventions: DRUG: naproxen sodium codein|DRUG: paracetamol codein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Lipopolysaccharide challenge|PROCEDURE: Saline challenge|PROCEDURE: Labelled neutrophils and Imaging assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effectiveness and Safety of Electromagnetic Navigation Real-time Guided Percutaneous Lung Biopsy
Status: NOT_YET_RECRUITING
Conditions: Peripheral Lung Lesions
Interventions: PROCEDURE: CT-guided percutaneous lung biopsy|PROCEDURE: Percutaneous lung biopsy guided by electromagnetic navigation real-time positioning technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)
Status: NOT_YET_RECRUITING
Conditions: Appendicitis With Peritonitis
Interventions: PROCEDURE: Use of hypnosis videos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Scaling and Root Planing on Serum Renal Function Markers in Chronic Periodontitis Subjects.
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: scaling and root planing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary Haemochromatosis
Status: COMPLETED
Conditions: Myocardial Iron Overload|HFE-Associated Hereditary Hemochromatosis
Interventions: DEVICE: 3Tesla cardiac MRI|DEVICE: Electrocardiogram (EKG)|BIOLOGICAL: Iron and cardiac markers|BIOLOGICAL: Pregnancy test|DEVICE: Echocardiography at rest|BIOLOGICAL: Urinary pregnancy test|DEVICE: 3Tesla abdominal MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Chronic Remote Ischemic Conditioning to Modify Post-MI Remodeling
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DEVICE: Auto Remote Ischemic Conditioning (AutoRIC) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anterior and Posterior Approaches of Suprascapular Nerve Block
Status: COMPLETED
Conditions: Shoulder Pain|Postoperative Pain|Diaphragmatic Paralysis|Subomohyoid Suprascapular Nerve Block|Anterior Suprascapular Nerve Block|Suprascapular Nerve Block
Interventions: PROCEDURE: Posterior suprascapular block|PROCEDURE: Anterior suprascapular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Oral Hygiene Routines on the Glycemic Control for Type 2 Diabetes Patients With Chronic Periodontitis
Status: UNKNOWN
Conditions: Periodontal Diseases|Diabetes Mellitus
Interventions: DEVICE: Electric toothbrush with smart phone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Radiation Therapy Before CAR T Cell Therapy for People With B Cell Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Non-Hodgkin's Lymphoma, Relapsed|Non-Hodgkin's Lymphoma Refractory
Interventions: RADIATION: Bridging radiotherapy (BRT)|DRUG: Conditioning chemotherapy|BIOLOGICAL: CAR T-cell product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Molar Incisor Hypomineralization With Silver Diamine Fluoride or SMART
Status: COMPLETED
Conditions: Dental Caries|Molar Incisor Hypomineralization
Interventions: DEVICE: SDF+KI|DEVICE: SDF+KI+GIC(SMART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study in Japan and Ex-Japan to Characterize the Pharmacokinetic and Pharmacodynamic Response to Orteronel (TAK-700) in Chemotherapy-Naive Participants With Castration-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Orteronel|DRUG: Orteronel Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiological Effect Of Platelet Rich Fibrin on the Healing of Periodontal Intrabony Periodontal Defects
Status: COMPLETED
Conditions: Chronic Periodontitis|Intrabony Periodontal Defect
Interventions: OTHER: Anorganic Bovine Bone Mineral (ABBM)|OTHER: Anorganic Bovine Bone Mineral and Platelet Rich Fibrin (PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lets Agree to Disagree on Operative vs Nonoperative Treatment for Distal Radius Fractures in the Elderly (LADON Radius)
Status: NOT_YET_RECRUITING
Conditions: Radius Fracture Distal
Interventions: PROCEDURE: operative treatment|PROCEDURE: non-operative treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Learning Outcome of Resuscitation Teamwork Training in Postgraduate Year Doctors and Nurses
Status: UNKNOWN
Conditions: Patient Care Team
Interventions: OTHER: board game-based teamwork training|BEHAVIORAL: simulation-based teamwork training|OTHER: lecture-based teamwork training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult Participants With Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: RO7070179
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bone Union Following Anterior Cervical Fusion Using a NovoMax™
Status: COMPLETED
Conditions: Intervertebral Disk Degeneration|Intervertebral Disk Displacement
Interventions: DEVICE: Cervios ChronOs|DEVICE: NovoMax™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Artificial Oocyte Activation Comparing Tow Different Agents
Status: COMPLETED
Conditions: Oocyte Fertilization
Interventions: OTHER: Artificial Oocyte activation|DRUG: Ca Ionophore|DRUG: Strontium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study in Women With Metastatic Breast Cancer Whose Cancer Has Gotten Worse After Anthracycline and Taxane Therapy
Status: COMPLETED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Edotecarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy
Status: UNKNOWN
Conditions: Periampullary Tumor|Common Bile Duct Neoplasms|Duodenal Neoplasms
Interventions: DRUG: Preoperative hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tolerance of Healthy Term Infants Fed Infant Formulas #4
Status: COMPLETED
Conditions: Healthy Term Infants
Interventions: OTHER: Hydrolysate based infant formula|OTHER: Investigational Infant Formula A|OTHER: Investigational Infant Formula B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Functional Electrical Stimulation Versus Spencer Technique in Patients With Adhesive Capsulitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Adhesive Capsulitis
Interventions: BEHAVIORAL: Transcutaneous electrical nerve stimulation (TENS)|DIAGNOSTIC_TEST: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Temperature Study in Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section|Hypothermia
Interventions: OTHER: Warmed fluids|OTHER: Fluid warmer and warming blanket|DEVICE: Belmont fluid warmer|DEVICE: Bair hugger warming blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance and Optical Imaging of Dystrophic and Damaged Muscle
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: Exercising|PROCEDURE: Optical and Magnetic Resonance Imaging and Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test if SAR443809 is Tolerated and Safe When Taken as a Single Dose in Healthy Adults
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Humanized anti-Factor Bb monoclonal antibody|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anxiety Lowering and Deprescribing Through Emotion Regulation
Status: RECRUITING
Conditions: Benzodiazepine Dependence|Anxiety Disorders|Sleep Disturbance
Interventions: BEHAVIORAL: ALDER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds
Status: RECRUITING
Conditions: Open Wound|Wound Heal
Interventions: DRUG: Micro/nanobubble (MNB) - Irrigation|OTHER: 0.9% Normal Saline - Irrigation|DRUG: Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi)|OTHER: 0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Dalteparin|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Of GSK679586A When Infused Into Healthy And Mild Asthmatic Volunteers
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK679586|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional Intelligence Skills Health Leaders Need During Covid-19
Status: UNKNOWN
Conditions: Emotional Intelligence|Leadership|Health Personnel Attitude|Covid-19
Interventions: BEHAVIORAL: EI Open ended Pre-Survey and Semi Structured Interview|BEHAVIORAL: Behavioral and Cognitive Assessment|BEHAVIORAL: Geneva Emotional Competence Test (GECO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: lIfestyle iNterventionS for PaIn ReliEf (INSPIRE)
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Inulin Fibre supplement|DIETARY_SUPPLEMENT: Maltodextrin (Placebo)|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antimicrobial Photodynamic Therapy in the Nasal Decolonization of Maintenance Hemodialysis Patients
Status: COMPLETED
Conditions: Photochemotherapy|Renal Insufficiency, Chronic
Interventions: DEVICE: Antimicrobial Photodynamic therapy|DRUG: Mupirocin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Obatoclax Mesylate (GX15-070MS)for the Treatment of Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Obatoclax mesylate (GX15-070MS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy Between Conservative Versus Operative Management of Carpel Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Conservative Approach|PROCEDURE: Surgical Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: TPI 287|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Neurorehabilitation Approaches Involving Different Upper Extremity Reactive Trainings in Stroke Patients
Status: RECRUITING
Conditions: Stroke|Spastic Hemiplegia
Interventions: DEVICE: reactive exercise training with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program|DEVICE: reactive exercise training with co-contraction with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program.|OTHER: neurorehabilitation program with functional reaching training without device.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis|Hemodialysis|Peritoneal Dialysis|Nonosmotic Sodium Storage
Interventions: COMBINATION_PRODUCT: Interdialytic peritoneal ultrafiltration with 10% dextrose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACCURATE Trial - Operative Treatment of Acute Rotator Cuff Tear Related to Trauma
Status: RECRUITING
Conditions: Acute Rotator Cuff Tear Related to Trauma
Interventions: PROCEDURE: Placebo surgery and supervised specific exercises|PROCEDURE: Rotator cuff repair and supervised specific exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversal of Residual Neuromuscular Blockade at Train-of-four Ratio 0.3 With Sugammadex and Neostigmine
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex|DRUG: Neostigmine|DRUG: Saline 0.9%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sympathetic Mapping/ Ablation of Renal Nerves Trial - Hemodialysis
Status: UNKNOWN
Conditions: Hypertension|Hemodialysis
Interventions: DEVICE: SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Aggression in Veterans With Dementia
Status: COMPLETED
Conditions: Dementia|Aggression|Pain
Interventions: BEHAVIORAL: PAVeD Intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: mitoxantrone hydrochloride|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn
Status: RECRUITING
Conditions: Persistent Pulmonary Hypertension of Newborn
Interventions: DRUG: Magnesium sulfate|DRUG: Sildenafil Citrate|OTHER: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer.
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Liver Cancer|Cirrhosis|Chronic Liver Disease
Interventions: OTHER: Liver ultrasound and fast-MRI|OTHER: Liver ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflation
Status: UNKNOWN
Conditions: COVID 19|SARS-CoV 2|Pneumonia
Interventions: DRUG: Mavrilimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Top-Down Holmium Laser Enucleation of the Prostate (HoLEP) vs the Traditional HoLEP for Treatment of Benign Prostatic Hyperplasia (BPH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: PROCEDURE: Traditional HoLEP|PROCEDURE: Top-Down HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Maintenance Treatment With Fluzoparib in gBRCA/PALB2 Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Fluzoparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the PEAC-IC: a Randomized Controlled Clinical Trial
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Program for Teaching Self-Care in HF (PEAC-IC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lateral Sagittal vs Costoclavicular Brachial Plexus Block in Children
Status: COMPLETED
Conditions: Hand Injuries and Disorders|Forearm Injuries
Interventions: DRUG: Lidocaine and Bupivacaine solution|DEVICE: Costoclavicular block|DEVICE: Lateral Sagittal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency
Interventions: DRUG: Canagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the Music Glove Patients With Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Music Glove|OTHER: Conventional Hand Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Alpha Lipoic Acid on Uterine Scar Healing After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section; Dehiscence|Cesarean Scar Niche
Interventions: DRUG: alpha lipoic acid drug (thioctic acid acid)|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors|Non-small Cell Lung Cancer|Renal Cell Carcinoma|Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib + Envafolimab|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canadian Cardiology de Novo Study: A Comparison Between Tacrolimus- and Cyclosporine- Based Immunoprophylactic Regimens
Status: COMPLETED
Conditions: Heart Diseases|Heart Transplantation
Interventions: DRUG: Tacrolimus|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil|DRUG: Methylprednisolone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coolsculpting With Cooltone Verses Coolsculpting Alone for the Banana Roll Area
Status: UNKNOWN
Conditions: Improved Appearance of the Banana Roll Region
Interventions: DEVICE: CoolSculpting Elite combined with CoolTone Treatments|DEVICE: CoolSculpting Elite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate Safety, Tolerability, and Pharmacokinetics of Treatment With BI 660848 Rising Single Doses (From 2 mg to 600 mg) Administered as Oral Drinking Solution (Powder in Bottle).
Status: TERMINATED
Conditions: Pain|Healthy
Interventions: DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: BI 660848|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Flouro-Gem in Adenocarcinoma of the Pancreas (GEFLUPAN)
Status: COMPLETED
Conditions: Cancer of Pancreas|Chemotherapy Effect|Metastatic Pancreatic Cancer
Interventions: DRUG: Gemcitabine fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled, Double-blind Multicenter Safety Study to Evaluate the Safety and Immunogenicity of Subcutaneous EPO HEXAL vs. ERYPO® in the Treatment of Anemia Associated With Chronic Renal Insufficiency in Predialysis Patients
Status: TERMINATED
Conditions: Anemia|Chronic Renal Insufficiency
Interventions: DRUG: HX575 recombinant human erythropoietin alfa|DRUG: ERYPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Mechanisms and Targeting Insomnia in Major Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder|Insomnia
Interventions: DRUG: escitalopram and eszopiclone|DRUG: Escitalopram, eszopiclone, and placebo|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of EPAP Device on Emphysema and Lung Bullae
Status: UNKNOWN
Conditions: Emphysema|Bullous Disease Lung
Interventions: DEVICE: use the face mask with Expiratory Positive Airway Pressure(EPAP).|DEVICE: use the face mask without Expiratory Positive Airway Pressure(EPAP).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Melanoma by AJCC V7 Stage
Interventions: PROCEDURE: Wide Local Excision = 1cm Margin|PROCEDURE: Wide Local Excision = 2cm Margin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate PROCRIT (Epoetin Alfa) for Maintenance Phase Treatment of Patients With Anemia Due to Chronic Kidney Disease (PROMPT)
Status: COMPLETED
Conditions: Anemia|Chronic Renal Insufficiency
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing PrEP Uptake and Adherence Among Male Sex Workers
Status: RECRUITING
Conditions: Prevention
Interventions: BEHAVIORAL: Stage 1 Strength Based Case Management (SBCM) Condition|BEHAVIORAL: Stage 2 PrEPare for Work Intervention Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics Study of Intraperitoneal Administration of Daptomycin in Peritoneal Infection
Status: COMPLETED
Conditions: Peritoneal Infection
Interventions: DRUG: intraperitoneal daptomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Cobimetinib|DRUG: Paclitaxel|DRUG: Placebo|DRUG: Atezolizumab|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Recurrent Childhood Ependymoma|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Medulloblastoma|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Childhood Osteosarcoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Hepatoblastoma|Recurrent Langerhans Cell Histiocytosis|Recurrent Malignant Glioma|Recurrent Malignant Solid Neoplasm|Recurrent Neuroblastoma|Recurrent Primary Central Nervous System Neoplasm|Recurrent Rhabdoid Tumor|Refractory Childhood Malignant Germ Cell Tumor|Refractory Childhood Osteosarcoma|Refractory Childhood Rhabdomyosarcoma|Refractory Childhood Soft Tissue Sarcoma|Refractory Ependymoma|Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Refractory Hepatoblastoma|Refractory Langerhans Cell Histiocytosis|Refractory Malignant Glioma|Refractory Malignant Solid Neoplasm|Refractory Medulloblastoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Primary Central Nervous System Neoplasm|Refractory Rhabdoid Tumor|Wilms Tumor
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Erdafitinib|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|OTHER: Pharmacological Study|PROCEDURE: Positron Emission Tomography|PROCEDURE: Radionuclide Imaging|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion Therapy of Disitamab Vedotin Combined With Sintilimab and S-1 in HER2 Overexpression Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Disitamab Vedotin|DRUG: Sintilimab|DRUG: S-1|PROCEDURE: Intraperitoneal chemotherapy with paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: DRUG: riboflavin ophthalmic solution|DEVICE: Vedera KXS Microwave System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Open-face Maxillary Complete Denture for Patients With Prominent Premaxilla
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: DEVICE: Conventional denture|DEVICE: Maxillary open-faced denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jovenes Sanos: Preventing IPV and RC
Status: COMPLETED
Conditions: Unintended Pregnancy|Family Planning|Intimate Partner Violence (IPV)
Interventions: BEHAVIORAL: Jovenes Sanos
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Take Off Pounds After Stroke Trial (TOPS)
Status: COMPLETED
Conditions: Stroke|Obesity|Overweight|Hemiparesis
Interventions: BEHAVIORAL: Partial meal replacement program|BEHAVIORAL: Dietary Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease
Status: RECRUITING
Conditions: PD - Parkinson's Disease|Dexmedetomidine|Desflurane|Deep Brain Stimulation
Interventions: DRUG: general anesthesia|DRUG: Conscious sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers
Status: COMPLETED
Conditions: Pressure Sore|Pressure Ulcer|Pressure Ulcers Stage III|Pressure Ulcers Stage II
Interventions: DEVICE: blue light photobiomodulation|PROCEDURE: cleansing|COMBINATION_PRODUCT: hyaluronic acid gauze plus polyurethane foam|DRUG: zinc cream or hyaluronic acid sodium salt + metallic silver|PROCEDURE: topical treatment|PROCEDURE: bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tools to Optimize Patient Presentation After Onset of Exudative Age-Related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Age-related Macular Degeneration
Interventions: BEHAVIORAL: VMS diary booklet|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Direct Tumor Injection KLH-Pulsed Dendritic Cells in Unresectable Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: BIOLOGICAL: KLH-pulsed autologous dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of a Personalized Neoantigen Cancer Vaccine
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Colorectal Cancer|Gastroesophageal Adenocarcinoma|Urothelial Carcinoma
Interventions: BIOLOGICAL: GRT-C901|BIOLOGICAL: GRT-R902|BIOLOGICAL: nivolumab|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Pharmacodynamic/Pharmacokinetic Characteristics of HIP2101 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Volunteer
Interventions: DRUG: HIP2101|DRUG: RLD2101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ningmitai Capsule Alone or Combined With Celecoxib in the Treatment of CP/CPPS
Status: NOT_YET_RECRUITING
Conditions: Chronic Prostatitis
Interventions: DRUG: Ningmitai capsule|DRUG: Celecoxib capsule|DRUG: Ningmitai placebo|DRUG: Celecoxib placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Coenzyme Q10 (CoQ) in Parkinson Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Coenzyme Q10 with vitamin E|DRUG: placebo with vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Study of a Peri-intervention Diabetes Management Algorithm (DIAPI) for Endoscopy Procedures
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: OTHER: Peri-intervention Diabetes Management Algorithm (DIAPI)|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Nutrition for Moderate to Late Preterm Infants
Status: RECRUITING
Conditions: Premature Birth|Breastmilk Collection|Postnatal Growth Restriction
Interventions: DIETARY_SUPPLEMENT: Targeted Fortification|DIETARY_SUPPLEMENT: Enfamil Liquid Human Milk Fortifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Turkish Music and Comedy Film on Pain, Vital Signs and Cortisol Level in Orthopedic Patients
Status: COMPLETED
Conditions: Physiological Parameter|Acute Pain
Interventions: OTHER: Turkish Music|OTHER: comedy movie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bioequivalence Study of Amlodipine Plus Losartan Versus Amlodipine and Losartan
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine plus Losartan|DRUG: Amlodipine, Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: