pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparative Effectiveness of Two Approaches to Diabetes Management in the Uninsured
Status: COMPLETED
Conditions: Diabetes
Interventions: OTHER: nurse-led care management or peer-led self management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pragmatic Approach To Esophageal Dilation
Status: COMPLETED
Conditions: Dysphagia|Swallowing Disorders
Interventions: PROCEDURE: Dilation 60-Fr non stricture|PROCEDURE: Sham|PROCEDURE: Non severe stricture - dilation with 60-Fr|PROCEDURE: Non severe stricture - dilation with 46-Fr|PROCEDURE: Severe stricture - dilation with 51-Fr|PROCEDURE: Severe stricture - dilation with 42-Fr
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Infant Forced Oscillations Technique (iFOT)
Status: UNKNOWN
Conditions: Respiratory Function Tests|Respiratory Disease|Infant, Newborn, Disease
Interventions: DIAGNOSTIC_TEST: FOT measurements in newborns and small infants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating Neoadjuvant Pembrolizumab Monotherapy in Patients With Muscle-Invasive Bladder Cancer to Explore in Vivo the Mechanisms of Action of Pembrolizumab
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate and Compare the Impact of High Protein Pasta, Lower Protein Pasta and White Rice on Blood Sugar Control in People With Type 1 Diabetes Mellitus (T1DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Regular pasta|OTHER: High protein pasta|OTHER: White rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Live Birth Rate Between ICSI and AOA and ICSI Alone in Patients With Severe Teratospermia
Status: NOT_YET_RECRUITING
Conditions: Male Infertility|Teratospermia
Interventions: PROCEDURE: intracytoplasmic sperm injection and artificial oocyte activation|PROCEDURE: intracytoplasmic sperm injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women
Status: UNKNOWN
Conditions: Morbid Obesity|Cesarean Delivery Affecting Fetus
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide for Pediatric Painful Sickle Crisis
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: nitric oxide|DRUG: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study Comparing Lamivudine Versus Adefovir Dipivoxil for Prevention of zHBV Reactivation in HBsAg Seropositive Patients Undergoing Cytotoxic Chemotherapy
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: adefovir dipivoxil|DRUG: lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Paclitaxel and Trastuzumab for Node-Negative HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Carcinoma of the Breast
Interventions: DRUG: Paclitaxel|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab in Combination With Bevacizumab and Temozolomide in Recurrent Glioblastoma (GBM) Patients
Status: RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Sintilimab plus Bevacizumab and Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3Mixstatin ,Tri-Antibiotic Mix & Simvastatin in the Treatment of Primary Molars
Status: UNKNOWN
Conditions: Tooth, Deciduous
Interventions: PROCEDURE: Pulpectomy for primary molars + triple antibiotic mix|PROCEDURE: Pulpectomy for primary molars + 3mixstatin|PROCEDURE: Pulpectomy for primary molars + simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema
Status: COMPLETED
Conditions: CORNEAL EDEMA
Interventions: DEVICE: Hyper-CL™ lens|DEVICE: Regular soft contact lens|DRUG: Salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Gemcitabine+Platinum Salt+Bevacizumab Combination for Metastatic Collecting Duct Carcinoma (GETUG-AFU 24)
Status: COMPLETED
Conditions: Collecting Duct Carcinoma (Kidney)
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DRUG: VI-0521|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 5% and 15% Dextrose Prolotherapy Efficacy in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: %5 dextrose prolotherapy|OTHER: %15 dextrose prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Regenerative Endodontic Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Endodontic Disease
Interventions: PROCEDURE: Regenerative Endodontic Procedures|OTHER: non-setting calcium hydroxide|OTHER: modified triple antibiotic paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Monitoring in Children and Adolescents With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis|Crohn´s Disease
Interventions: BEHAVIORAL: Web-monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: esomeprazole 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PVAC GOLD Versus Irrigated RF Single Tip Catheter With Contact FORCE Ablation of the Pulmonary Veins for Treatment of Drug Refractory Symptomatic Paroxysmal and Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: PVAC GOLD multielectrode catheter|DEVICE: Contact Force single-tip ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transnasal Humidified Rapid Insufflation System for Intubation
Status: UNKNOWN
Conditions: Hypoxemia
Interventions: DEVICE: Transnasal humidified rapid insufflation ventilator exchange|DEVICE: Conventional face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide+Metformin|DRUG: Temozolomide+Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine in Population Aged ≥18 Years
Status: UNKNOWN
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: BIOLOGICAL: SCTV01E|BIOLOGICAL: Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Everolimus trIal for Advanced prememopausaL Breast Cancer Patients
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Goserelin|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Rituximab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation Surgery for the Treatment of Refractory Obsessive-Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Deep Bran Stimulation (DBS)|DEVICE: Sham-stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants
Status: TERMINATED
Conditions: Ovarian Neoplasms
Interventions: BIOLOGICAL: Tilvestamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Surface Materials (Tantalum Versus Titanium Fiber Mesh) of Acetabular Components in Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Acetabular implant, Monoblock cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Pelvic Floor Prevention (3PN)
Status: COMPLETED
Conditions: Urinary Incontinence|Anal Incontinence|Genital Prolapse
Interventions: OTHER: Pelvic floor muscle training with physiotherapist|OTHER: Written information about kegel exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Endovascular Versus Open Repair of the Common Femoral Artery
Status: COMPLETED
Conditions: Atherosclerotic Lesions of the Common Femoral Artery
Interventions: DEVICE: Endovascular treatment using self expandable nitinol STENTS|DEVICE: Open repair treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)
Status: COMPLETED
Conditions: Invasive Aspergillosis
Interventions: DRUG: Posaconazole IV|DRUG: Posaconazole PFS|DRUG: Posaconazole tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Actinic Keratoses (AK) on the Face
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: ingenol mebutate 0.015%|OTHER: dermasil lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism|Autistic Disorder|Autism Spectrum Disorder|Autistic Behavior
Interventions: DRUG: Sulforaphane|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Countermeasures to Circadian Misalignment
Status: RECRUITING
Conditions: Circadian Rhythm Sleep Disorder of Shift Work Type|Metabolic Disease|Insulin Sensitivity
Interventions: BEHAVIORAL: Time-restricted feeding|BEHAVIORAL: Circadian Misalignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Grade 3b Follicular Lymphoma|Recurrent High Grade B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Transformed Chronic Lymphocytic Leukemia|Recurrent Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Grade 3b Follicular Lymphoma|Refractory High Grade B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Refractory Transformed Chronic Lymphocytic Leukemia|Refractory Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Loncastuximab Tesirine|BIOLOGICAL: Mosunetuzumab|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma
Status: TERMINATED
Conditions: Stage III Melanoma|Stage IV Melanoma
Interventions: BIOLOGICAL: MKC1106-MT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HY-0102 Monotherapy in Patients With Locally Advanced/Metastatic Solid Tumours
Status: COMPLETED
Conditions: Locally Advanced/Metastatic Solid Tumors
Interventions: DRUG: HY-0102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Manual Therapy and Exercise|OTHER: Exercise Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antenatal Education on Fear of Birth, Physiological Ability to Give Birth and Traumatic Birth Perception
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers|Pregnancy Trimester, Second|Pregnancy Trimester, Third|Nulliparity
Interventions: BEHAVIORAL: Antenatal training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RApid Fluid Volume EXpansion in Patients in Shock After the Initial Phase of Resuscitation.
Status: RECRUITING
Conditions: Shock|Hypovolemia
Interventions: DRUG: fluid bolus|DEVICE: PiCCO system (Pulsion, Germany)|DEVICE: Vascular pressure transducers (Edwards Life Science, USA)|OTHER: Passive Leg Raising test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 300 mg|DRUG: Antihyperglycemic agent(s)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate|DRUG: Abiraterone acetate plus degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Rehabilitation Sport After Total Hip Arthroplasty (THA)
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Osteoarthritis, Hip|Sports Physical Therapy
Interventions: BEHAVIORAL: rehabilitation sport
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders
Status: RECRUITING
Conditions: Schizophrenia|Schizophreniform Disorders|Delusional Disorder|Brief Psychotic Disorder|Schizoaffective Disorder|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: BEHAVIORAL: Cognitive Remediation (REHACOP)|BEHAVIORAL: Metacognitive Training (MCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Isoflurane and Sevoflurane Comparison in Cardiac Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Valvular Heart Disease
Interventions: DRUG: Volatile anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Site Trial of Navigation vs Treatment as Usual for Delays in Starting Adjuvant Therapy
Status: RECRUITING
Conditions: Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Oropharynx Cancer|Oral Cavity Cancer|Larynx Cancer
Interventions: BEHAVIORAL: ENDURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dipeptidyl Peptidase-4 Inhibition and Immune Function in HIV
Status: COMPLETED
Conditions: Diabetes|Insulin Resistance
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Yogurt Study in Children 2-4 Years Old Attending Daycare
Status: COMPLETED
Conditions: Infections, Respiratory|Diarrhea
Interventions: OTHER: probiotic strain Bb-12|OTHER: no Bb-12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures
Status: COMPLETED
Conditions: Partial Epilepsies|Partial Onset Seizures
Interventions: DRUG: lacosamide|DRUG: lacosamide|DRUG: lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Clinical Study of NKG2D-CAR-NK Cells for the Treatment of Refractory Recurrent Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: NKG2D Chimeric Antigen Receptor NK Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.
Status: COMPLETED
Conditions: Safety of Intervention|Efficacy of Intervention|Cost Effectiveness
Interventions: PROCEDURE: VATS hyperthermic chemoperfusion|PROCEDURE: Bedside talc slurry pleurodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin-D Insufficiency and Implants
Status: COMPLETED
Conditions: Vitamin D Deficiency|Osseointegration Failure of Dental Implant|Peri-Implantitis
Interventions: DIAGNOSTIC_TEST: OPG, OC, RANKL, IL-10, IL-1β, Ca, TNF-α and Caspase-1 ELISA|DIAGNOSTIC_TEST: Resonance Frequency Analysis|DIAGNOSTIC_TEST: Periodontal clinical examination|PROCEDURE: Dental implant placement and bone sample collection|PROCEDURE: Gingival Crevicular Fluid Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Elsiglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Acupressure on Interventional Pain in Infants
Status: COMPLETED
Conditions: Procedural Pain|Child, Only
Interventions: PROCEDURE: Acupressure|PROCEDURE: Placebo Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Obeticholic Acid for Prevention in Barrett's Esophagus
Status: RECRUITING
Conditions: Barrett Esophagus
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Esophageal Biopsy|PROCEDURE: Esophagogastroduodenoscopy|PROCEDURE: Liver Ultrasonographic Elastography|BIOLOGICAL: Obeticholic Acid|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Axillary Vein Puncture With Subclavian Vein Puncture in Pacemaker Implantation
Status: UNKNOWN
Conditions: Mechanical Complication of Cardiac Pacemaker
Interventions: DEVICE: Placement of electrode lead through axillary vein puncture|DEVICE: Placement of electrode lead through subclavian vein puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Potential Effects of Liraglutide on Degenerative Changes
Status: COMPLETED
Conditions: Alzheimers Disease
Interventions: DRUG: Liraglutide|DRUG: non-active study drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unicompartmental Knee Arthroplasty (UKA) Versus Total Knee Arthroplasty (TKA) of Medial Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Total Knee Arthroplasty (TKA)|PROCEDURE: Unicompartmental Knee Arthroplasty (UKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Japanese Men to Test How Different Doses of BI 1323495 Are Tolerated and How Itraconazole Influences the Amount of BI 1323495 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1323495|DRUG: Placebo|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CCX168 in Healthy Participants
Status: COMPLETED
Conditions: Vasculitis|Systemic Lupus Erythematosus (SLE)
Interventions: DRUG: CCX168|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Abdominal Wall Block|PROCEDURE: Surgical infiltration|DRUG: Sterile saline|DRUG: Ropivacaine 0.2%|DEVICE: Ultrasound|DRUG: Ropivacaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
Status: RECRUITING
Conditions: PreDiabetes|Adult Children
Interventions: DRUG: Metformin|BEHAVIORAL: Digital Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of Booster Doses of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received One or Four Doses of the Same Vaccine
Status: COMPLETED
Conditions: Meningococcal Disease
Interventions: BIOLOGICAL: Meningococcal (group B) multicomponent recombinant adsorbed vaccine.|BIOLOGICAL: Meningococcal (group B) multicomponent recombinant adsorbed vaccine, without Outer Membrane Vesicles (OMV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 30 Day Acute Efficacy and Safety Study of Chromium Picolinate + Biotin on Glycemic Control in Overweight or Obese Subjects With T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Chromium Picolinate (600 mcg Cr+3) + biotin (2 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation With Putty Allografts
Status: COMPLETED
Conditions: Tooth Loss
Interventions: PROCEDURE: Combined Mineralized/Demineralized Putty Allograft|PROCEDURE: Demineralized Putty Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Ovarian Epithelial Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Exercise Training and Glucose Metabolism in Aging
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Impaired Glucose Tolerance (Prediabetes)
Interventions: BEHAVIORAL: Aerobic exercise training|BEHAVIORAL: Detraining (cessation of exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Extra Virgin Olive Oil Supplementation in Pregnancies With Increased Cholesterol Levels
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Extra Virgin Olive Oil (EVOO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: VELCADE in Previously Treated Patients With Stage IIIB and IV Bronchioloalveolar Carcinoma (BAC) and Adenocarcinoma With BAC Features
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Adenocarcinoma, Bronchiolo-Alveolar
Interventions: DRUG: VELCADE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
Status: RECRUITING
Conditions: Bone or Joint Infection
Interventions: DRUG: Afabicin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Approach of Loco Regional Analgesia in Kidney Transplant
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: PROCEDURE: efficacy of quadratus lumborum block in post-operative analgesia in kidney transplant surgery|PROCEDURE: general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Benidipine-based Comparison of Angiotensin Receptors, β-blockers, or Thiazide Diuretics in Hypertensive Patients
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Angiotensin receptor blockers|DRUG: β-blockers|DRUG: thiazide diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Regional Anesthesia|Hip Dysplasia
Interventions: PROCEDURE: Erector spinae block with ropivacaine 0.2%|PROCEDURE: Quadratus lumborum block with ropivacaine 0.2%|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Assessment and Practice Support System in Home Care Services for Older Adults
Status: COMPLETED
Conditions: Chronic Disease|Life-limiting Illness|Palliative Care
Interventions: OTHER: QPSS|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Serotonergic Function and Behavioural and Psychological Symptoms of Frontotemporal Dementia
Status: COMPLETED
Conditions: Frontotemporal Dementia
Interventions: DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: PSMA PET/MR - Gallium-68 labeled PSMA-HBED-CC|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 10 mg Xanamem on Dementia Due to Alzheimer's Disease
Status: RECRUITING
Conditions: Dementia Moderate|Dementia, Mild|Alzheimer Disease
Interventions: DRUG: Xanamem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: L-Theanine in the Management of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: L-Theanine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins
Status: TERMINATED
Conditions: Cavernous Angioma, Familial|Cerebral Cavernous Malformations|Cerebral Cavernous Hemangioma
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Evaluation of the ForConti Contix Fecal Incontinence Management System (FIMS)
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: DEVICE: ForConti Contix Fecal Incontinence Management System (FIMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Time in Human (FTIH) Study of GSK3008348 in Healthy Volunteers and Idiopathic Pulmonary Fibrosis Patients
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GSK3008348 Nebuliser solution|DRUG: Placebo Nebuliser solution|RADIATION: GSK26346763: ([18F]-FBA-A20FMDV2) IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of PAT-1251 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PAT-1251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy, Safety and Palatability of the Syrup "KalobaTuss® Children" for the Treatment of Cough in Children
Status: COMPLETED
Conditions: Cough
Interventions: DIETARY_SUPPLEMENT: KalobaTuss children|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Neoadjuvant Chemoimmunotherapy|Radical Hysterectomy|Fertility Preservation
Interventions: DRUG: Cadonilimab|DRUG: Paclitaxel-albumin|DRUG: Cisplatin|PROCEDURE: Extrafascial hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cooling Pillow for Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: OTHER: Current standard eczema treatment and standard pillow at night|OTHER: Chillow cooling pillow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Controlled Trial of Ultrasound-guided Platelet-Rich-Plasma (PRP) Injection Versus Extracorporeal Shock Wave Therapy (ESWT) for Great Trochanter Pain Syndrome (GTPS) With Gluteus Medius or Minimus Tendinopathy
Status: WITHDRAWN
Conditions: Greater Trochanter Pain Syndrome, Gluteus Medius Tendinopathy, Gluteus Minimus Tendinopathy
Interventions: BIOLOGICAL: Platelet-Rich Plasma Injection|DEVICE: Extracorporeal Shock Wave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vitamin D Supplementation Combined With Standard Behavioral Therapy in the Treatment of OAB-dry in Children
Status: NOT_YET_RECRUITING
Conditions: Overactive Bladder|Pediatric Disorder
Interventions: DRUG: Solifenacin|DIETARY_SUPPLEMENT: vitamin D|BEHAVIORAL: Standard behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With OA
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Total Hip Arthroplasty|Prosthetic-joint Infection
Interventions: OTHER: Antibiotic dosage practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of BCMA-Targeted CAR-T Therapy for Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse|Neoplasm, Plasma Cell
Interventions: BIOLOGICAL: BCMA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ozurdex® Compared to Lucentis® in Patients With Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Macular Edema
Interventions: DRUG: dexamethasone intravitreal implant|BIOLOGICAL: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate vs Conventional Loading for Early Implant Placement
Status: RECRUITING
Conditions: Dental Implant
Interventions: DEVICE: Early implant placement with immediate provisional restoration|DEVICE: Early implant placement with delayed loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Uptake of 18F Florbetapir in Patients Undergoing Chemotherapy
Status: TERMINATED
Conditions: Cardiac Amyloidosis
Interventions: DRUG: F18 Florbetapir (amyvid) cardiac PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use
Status: RECRUITING
Conditions: Underage Drinking|Cannabis Use|Drinking, Teen|Drinking, College|College Drinking|Teen Drinking
Interventions: BEHAVIORAL: e-PBI+|BEHAVIORAL: e-PBI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: DRUG: Dexmedetomidine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Neuromuscular Electrostimulation on Sympathetic Nerve Activity in Patients With Type 2 Diabetes (ELECTROSYMP2)
Status: WITHDRAWN
Conditions: Type 2 Diabetes|Insulin Resistance
Interventions: DEVICE: effect of neuromuscular electrostimulation (NMES)|DEVICE: effect of neuro electrostimulation (NES)|OTHER: effect of voluntary contractions (VC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Status: COMPLETED
Conditions: Dentine Hypersensitivity
Interventions: DRUG: Stannous Fluoride|DRUG: Sodium Monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Immunoglobulin G4 Related Disease
Interventions: DRUG: rilzabrutinib|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type 1 Endoleak : Fenestrated Custom Made Endograft (FEVAR) Versus Open Surgery Explantation (OSR) : What's the Best
Status: COMPLETED
Conditions: Aorta Aneurysm
Interventions: DEVICE: FEVAR|DEVICE: Explantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Anemia Control Program: High or Low Iron Supplementation
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Cognitive Development|Motor Development
Interventions: DIETARY_SUPPLEMENT: Low-iron formula|DIETARY_SUPPLEMENT: High-iron formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Fosamax Plus D in Postmenopausal Women With Osteoporosis (0217A-263)
Status: COMPLETED
Conditions: Osteoporosis Postmenopausal
Interventions: DRUG: alendronate sodium (+) cholecalciferol|DRUG: Comparator: Alendronate sodium (Fosamax)|DIETARY_SUPPLEMENT: Comparator: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Inferior Cervical Sympathetic Block for Treatment of Refractory Ventricular Tachycardia
Status: WITHDRAWN
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: Percutaneous inferior cervical sympathetic block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Simvastatin 20mg plus ezetimibe 10mg|DRUG: ezetimibe|DRUG: simvastatin 20mg|DRUG: Simvastatin 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Toxicities of Immune ChecKpoint Inhibitors : From Bed to Benchside
Status: RECRUITING
Conditions: Renal Cell Carcinoma|Bladder Cancer|MSI-H Cancer|Cancer
Interventions: DIAGNOSTIC_TEST: Arterial Doppler for Flow Mediated Reserve measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Counseling Patient Preference Intervention Versus Conventional Genetic Counseling for Women at Elevated Risk for Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma
Interventions: OTHER: Educational Intervention|OTHER: Genetic Counseling|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recovering From Bariatric Surgery: the Effects of Early Initiated and Supervised Mobilization
Status: RECRUITING
Conditions: Postoperative Pain, Acute|Postoperative Pain, Chronic|Bariatric Surgery|Mobilization|Physical Activity
Interventions: OTHER: Intervention 1: Mobilization during hospitalization|OTHER: Intervention 2: Mobilization the first 4 postoperative weeks|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
Status: ENROLLING_BY_INVITATION
Conditions: Lumbar Disc Herniation|Lumbar Disc Disease|Lumbar Radiculopathy
Interventions: DRUG: General anesthetic|DRUG: SA + ESP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Injury Versus Luteal Phase Support in Intrauterine Insemination Cycles
Status: TERMINATED
Conditions: Pregnancy
Interventions: OTHER: Endometrial Injury|DRUG: progesterone (Crinone® %8 vaginal progesterone gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: "Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C"
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Blood Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mouthrinse
Status: COMPLETED
Conditions: Mild Gingivitis|Periodontal Diseases|Plaque
Interventions: OTHER: Licorice|OTHER: Hypertonic salt solution|OTHER: Essential oil|OTHER: Chlorhexidine Gluconate|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants
Status: COMPLETED
Conditions: Gastric Residual Volume|Preterm Infant|Feeding Disorder Neonatal
Interventions: OTHER: No Gastric residual volume monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Study to Learn More About How Safe Treatment With Rivaroxaban is in Children in Japan With Venous Thromboembolism
Status: RECRUITING
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban granules for oral suspension|DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gait Analysis in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis|3D Gait Analysis|Vestibular Rehabilitation
Interventions: OTHER: Vestibular exercises|OTHER: Standard neurorehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol)
Status: RECRUITING
Conditions: Thoracic Tumors|Non-small Cell Lung Cancer
Interventions: DRUG: AMG 193|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pembrolizumab|DRUG: Pemetrexed|DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD6474(Vandetanib) + Alimta Combo Study
Status: COMPLETED
Conditions: Carcinoma|Non-Small Cell Lung|Lung Cancer
Interventions: DRUG: ZD6474 (vandetanib) 100mg|DRUG: pemetrexed|DRUG: ZD6474 (vandetanib) 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT