pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Novel Technology-assisted Home Based Aerobic Exercise Programme for Individuals With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Combat PD|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Surveillance Study of Docetaxel-Based Chemotherapy
Status: COMPLETED
Conditions: Nonsmall Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Nolbaxol|DRUG: Taxotere|DRUG: cisplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detection of Circulating Tumor Cells for the Diagnostic of Pancreatic Adenocarcinoma.
Status: UNKNOWN
Conditions: Circulating Tumor Cells|Pancreatic Adenocarcinoma|Circulating Tumor DNA (KRAS)|CA 19.9
Interventions: OTHER: Pancreatic adenocarcinoma diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HS-WBRT for Prophylactic Cranial Irradiation in Limited Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Small Cell Lung
Interventions: RADIATION: HS-WBRT PCI|RADIATION: Conventional PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prediction of ARrhythmic Events With Positron Emission Tomography II
Status: ACTIVE_NOT_RECRUITING
Conditions: Sudden Cardiac Arrest|Ischemic Cardiomyopathy|Congestive Heart Failure
Interventions: DIAGNOSTIC_TEST: PET scan quantifying sympathetic denervation using [18F]-LMI1195
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure
Status: WITHDRAWN
Conditions: Respiratory Failure|Neuromuscular Disease|Chest Wall Disorder|Chronic Obstructive Pulmonary Disease|Obesity Hypoventilation Syndrome
Interventions: DEVICE: AutoVPAP™|DEVICE: VPAPIIIST-A™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Ceftriaxone Plus Azithromycin Versus Ceftriaxone for the Treatment of Gonorrhea
Status: COMPLETED
Conditions: Neisseria Gonorrhoeae
Interventions: DRUG: Rocephin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Association of Beta-2 Adrenergic Agonist and Corticosteroid Injection in the Treatment of Lipomas
Status: COMPLETED
Conditions: Lipoma
Interventions: DRUG: Prednisolone synthetic cortisone and Isoproterenol together
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IM Ketorolac vs Cambia for the Acute Treatment of Severe Migraine
Status: UNKNOWN
Conditions: Migraine Headache
Interventions: DRUG: Diclofenac postassium powder for oral solution and placebo injection|DRUG: Ketorolac intramuscular injection and placebo oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of an Interscalene Nerve Block With or Without Stellate Ganglion Block for Shoulder Surgery
Status: COMPLETED
Conditions: Anesthesia, Regional
Interventions: DRUG: Levobupivacaine|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells Delivered in Patients With Renal Failure
Status: WITHDRAWN
Conditions: Renal Failure
Interventions: PROCEDURE: Harvesting and Isolation of Stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
Status: NOT_YET_RECRUITING
Conditions: Acquired Antithrombin Deficiency
Interventions: DRUG: Human plasma derived antithrombin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA
Status: RECRUITING
Conditions: Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma|Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|RADIATION: Diffusing Alpha-emitter Radiation Therapy|DRUG: Docetaxel|PROCEDURE: Intensity-Modulated Proton Therapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Modified Barium Swallow Study|OTHER: Observation|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test and Treat COVID 65plus+
Status: WITHDRAWN
Conditions: SARS-CoV 2|COVID-19
Interventions: DRUG: Hydroxychloroquine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study)
Status: RECRUITING
Conditions: Respiratory Depression Neonatal
Interventions: OTHER: LIVEBORN: A Mobile Health Application (app) for Newborn Resuscitation|DEVICE: NeoBeat: Heart Rate Meter for Newborn Resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children on Antibiotics
Status: COMPLETED
Conditions: Antibiotic-associated Diarrhea
Interventions: BIOLOGICAL: Bifidobacterium animalis subsp. lactis BB-12|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Oral TXA in Reducing Blood Loss and Transfusion in Hip Fractures
Status: TERMINATED
Conditions: Hip Fractures|Blood Loss
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Targeting ATR in Soft-tissue Sarcomas
Status: RECRUITING
Conditions: Leiomyosarcoma, Adult
Interventions: DRUG: Association of berzosertib with gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding
Status: COMPLETED
Conditions: Herpes Simplex Type II
Interventions: DRUG: TDF|DRUG: Placebo Vaginal Gel|DRUG: Vaginal TFV Gel|DRUG: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of HM781-36B in Patients With Metastatic/Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) After Failure of or Unfit for Platinum-containing Therapy
Status: UNKNOWN
Conditions: HNSCC
Interventions: DRUG: HM781-36B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Clinical Outcome of Cortical Bone Trajectory Compared With the Traditional "Open" and Minimal Invasive Posterior Lumbar Interbody Fusion
Status: RECRUITING
Conditions: Degenerative Spondylolisthesis|Spondylolytic Spondylolisthesis
Interventions: PROCEDURE: Posterior Lumbar Interbody Fusion (PLIF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BioCurrent Electrical Stimulation for the Treatment of Dry ARMD
Status: WITHDRAWN
Conditions: Dry Macular Degeneration
Interventions: DEVICE: Electrical Stimulation of the Retina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Free Aminoacids in Saliva as A Diagnostic Biomarker of Periodontal Disease
Status: COMPLETED
Conditions: Periodontitis|Diagnoses Disease
Interventions: OTHER: Saliva collection of patients and salivary free amino acids analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Safety and Efficacy of the Addition of A New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Etoposide and Cisplatin) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma
Status: RECRUITING
Conditions: Advanced NUT Carcinoma|Metastatic NUT Carcinoma|Unresectable NUT Carcinoma
Interventions: DRUG: BET Bromodomain Inhibitor ZEN-3694|PROCEDURE: Biopsy|PROCEDURE: Chest Radiography|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Etoposide|PROCEDURE: FDG-Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT)
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: DRUG: acetylsalicylic acid|DRUG: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With Chemotherapy in Refractory MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Nivolumab|DRUG: Azacitidine|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: all trans retinoic acid|DRUG: Sildenafil|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Small Bowel Polyps in Patients With Sporadic Duodenal Adenomas
Status: COMPLETED
Conditions: Polyps
Interventions: DEVICE: Small bowel video capsule endoscopy (VCE) GIVEN/COVIDIEN LTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Managing Pain and Symptom Burden Caused by Chemotherapy in People With Myeloma or Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Hodgkin Disease|Non-Hodgkin Lymphoma
Interventions: OTHER: Acupuncture|DRUG: opioid|OTHER: Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lenvatinib (E7080) in Unresectable Biliary Tract Cancer (BTC) Who Failed Gemcitabine-based Combination Chemotherapy
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Integrated Population (I-POP) Health Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Hypertension|Chronic Kidney Diseases|Obesity|Chronic Disease
Interventions: OTHER: Usual Care|OTHER: I-POP + CHW navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726)
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis|Obstructive Sleep Apnea|Sleep Disorder
Interventions: DRUG: Mometasone furoate nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Exenatide Once Weekly Suspension in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Exenatide once weekly suspension|DRUG: Exenatide twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suprapubic Single-incision Laparoscopic Appendectomy Versus Conventional Appendectomy: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Complications
Interventions: PROCEDURE: suprapubic single-incision laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entarik Feeding Tube System Placement in Adult ICU
Status: RECRUITING
Conditions: Nasogastric Tube
Interventions: DEVICE: Entarik Feeding Tube System|DEVICE: Entarik Feeding Tube System without monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: Apalutamide|DRUG: Bicalutamide|DRUG: Bicalutamide Placebo|DRUG: Apalutamide Placebo|DRUG: GnRH (agonist)|RADIATION: 74-80 Grays (units of radiation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Tiragolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Neoadjuvant Chemoradiotherapy|DRUG: Total Neoadjuvant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Patient-Provider Communication (TPPC): Evaluating the Impact of TPPC in Dermatology Patients
Status: COMPLETED
Conditions: Psoriasis|Atopic Dermatitis|Acne
Interventions: OTHER: Tailored Patient-Provider Communication|OTHER: Non-Tailored Patient-Provider Communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Epoetin Alfa or Epoetin Beta With or Without Iron Infusion in Treating Anemia in Patients With Cancer
Status: UNKNOWN
Conditions: Anemia|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: epoetin alfa|BIOLOGICAL: epoetin beta|DIETARY_SUPPLEMENT: iron dextran complex|DIETARY_SUPPLEMENT: iron sucrose injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinomas|Cervix Cancer|Cervical Cancer
Interventions: DRUG: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Tipranavir and Ritonavir or Tipranavir and Ritonavir on the Pharmacokinetic Characteristics of Zidovudine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir (TPV) low|DRUG: Ritonavir (RTV) low|DRUG: Tipranavir (TPV) high|DRUG: Ritonavir (RTV) high|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of AZD9291 on the Blood Levels of Rosuvastatin, in Patients With EGFRm+ Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Pharmacokinetic sampling - AZD9291|DRUG: AZD9291 tablet dosing|DRUG: Rosuvastatin|PROCEDURE: Pharmacokinetic sampling - rosuvastatin|PROCEDURE: Pharmacokinetic sampling - AZ5140 and AZ7550
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury
Status: RECRUITING
Conditions: Fecal Incontinence
Interventions: DEVICE: Genital Nerve Stimulation|DIAGNOSTIC_TEST: Clinical exam|DIAGNOSTIC_TEST: Collection of SCI common data elements|DIAGNOSTIC_TEST: Bowel function survey completion|DIAGNOSTIC_TEST: International Standard for Neurological Classification of SCI (ISNCSCI)|DIAGNOSTIC_TEST: Response to genital nerve stimulation (GNS)|DIAGNOSTIC_TEST: Anorectal Manometry testing (ARM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of the DIAMOND System to Treat Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: DIAMOND System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bilateral Sphenopalatine Ganglion Block on Postoperative Pain in Patients to be Subject to Septorhinoplasty Surgery
Status: COMPLETED
Conditions: Anesthesia of Mucous Membrane
Interventions: PROCEDURE: Bilateral endoscopic sphenopalatine ganglion block|PROCEDURE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early Surgery
Status: UNKNOWN
Conditions: Mitral Regurgitation
Interventions: PROCEDURE: Mitral valve replacement|DEVICE: Speckle tracking echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of a Classroom-based Sensitization Intervention on Demand for Mental Health Care Among Adolescents in India
Status: COMPLETED
Conditions: Help-Seeking Behavior
Interventions: BEHAVIORAL: Classroom sensitization session|BEHAVIORAL: School-level sensitization activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nab-Paclitaxel Treatment in Advanced Squamous Cell Carcinoma of Lung
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Albumin paclitaxel plus carboplatin|DRUG: Gemcitabine plus carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Pain Management of Hemodialysis Patients
Status: TERMINATED
Conditions: End-stage Renal Disease|Chronic Kidney Disease
Interventions: OTHER: Individualized acupuncture treatment|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Carbohydrate Portfolio or "Eco-Atkins" Diet
Status: COMPLETED
Conditions: Hypercholesterolemia|Cardiovascular Diseases
Interventions: OTHER: Eco-Atkins diet (high vegetable protein and vegetable fat)|OTHER: NCEP diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Bio-Psychosocial Impact of Mobile App for Diabetes Type 1 ("SOCIAL DIABETES")
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Social Diabetes App|DEVICE: Usual clinical monitoring group (Control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mirror Therapy and Bilateral Arm Training on Hemiparetic Upper Extremity in Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: BEHAVIORAL: Mirror Therapy|BEHAVIORAL: Bilateral arm training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of C-Wave™ Peripheral Lithoclasty System Catheter System
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: C-wave™ peripheral seismic waveguide system|DEVICE: Peripheral vascular balloon dilatation catheter (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations
Status: RECRUITING
Conditions: Solid Tumor|Haematological Malignancy|Colorectal Neoplasms|Urinary Bladder Neoplasm|Gallbladder Neoplasms|Salivary Gland Neoplasm|Lung Neoplasm|Pancreatic Neoplasm|Ovarian Neoplasms|Prostatic Neoplasm|Skin Neoplasm
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Muscle Wasting and Rheumatoid Arthritis Flares
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Amino Acid Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality and Autobiographical Recall in Anorexia Nervosa: a Preliminary Study
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Emerging Technologies and Training in Neurosciences
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intracervical Block During Laminaria Insertion
Status: NOT_YET_RECRUITING
Conditions: Late Abortion|Dilation and Evacuation
Interventions: PROCEDURE: Intracervical block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Two Radiation Dose Schedules of SBRT to Lung Metastases < 5cm in Dimension
Status: WITHDRAWN
Conditions: Neoplasm Metastasis|Cancer|Radiation Therapy Complication
Interventions: RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tagraxofusp and Azaxitadine With or Without Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Tagraxofusp (Cycles 1-2)|DRUG: Azacitidine|DRUG: Tagraxofusp (Cycles 3-12)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Maxillary Stability in Bimaxillary Orthognathic Patients Using the Inverted Sequence Approach
Status: COMPLETED
Conditions: Class III Malocclusion
Interventions: PROCEDURE: the mandible first|PROCEDURE: the maxilla first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Papillary Epinephrine Spraying for the Prevention of Post-ERCP Pancreatitis in Patients Received Octreotide
Status: UNKNOWN
Conditions: Post-ERCP Acute Pancreatitis|Epinephrine
Interventions: PROCEDURE: Epinephrine sprayed on the papilla|PROCEDURE: Saline sprayed on the papilla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy
Status: UNKNOWN
Conditions: Breast Cancer|Chemotherapy|Neutropenia
Interventions: OTHER: EW02
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BIO-2-HEART: Identification of Biomarkers in T2DM and Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Diabetes Mellitus, Type 2
Interventions: DIAGNOSTIC_TEST: 6-minute walk test|DIAGNOSTIC_TEST: Study specific questionnaire|PROCEDURE: Blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 2L Oral Bi-PegLyte Versus 2L Oral MoviPrep Regimen for Outpatient Colonic Preparation
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Polyethylene Glycol (PEG) and 15 mg Bisacodyl|DRUG: Polyethylene Glycol (PEG) + ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Move for Your Mind - Pilot Trial
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Mild Dementia|Fall Prevention
Interventions: DRUG: Vi-De 3|OTHER: Jaques-Dalcroze eurhythmics|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Metacognitive Interpersonal Therapy (MIT-SA)|BEHAVIORAL: Clinical Structured Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cosmesis, Patient Satisfaction and Quality of Life After da Vinci Single Site and Multiport Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Symptomatic Gallbladder Disease
Interventions: PROCEDURE: Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: PROCEDURE: Sirolimus Drug-eluting Stent via Active Transfer of Plaque|PROCEDURE: Sirolimus Drug-eluting Stent implantation via Provisional T Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Surufatinib Combination With Toripalimab in Patients With Recurrent Biliary Tract Cancer
Status: UNKNOWN
Conditions: Biliary Tract Cancer
Interventions: DRUG: Surufatinib Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAgnetic Gastrointestinal Universal Septotome: a Safety and Feasibility Study (MAGUS)
Status: COMPLETED
Conditions: Diverticulum, Esophageal|Post Gastric Surgery Syndrome
Interventions: DEVICE: MAGUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment
Status: RECRUITING
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Follicular Lymphoma|Recurrent Indolent Adult Non-Hodgkin Lymphoma|Recurrent Marginal Zone Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Follicular Lymphoma|Refractory Indolent Adult Non-Hodgkin Lymphoma|Refractory Marginal Zone Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Lenalidomide|BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab and Hyaluronidase Human
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Postoperative|Excavatum, Pectus|Scoliosis Idiopathic
Interventions: BEHAVIORAL: Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension in Pregnancy|Postpartum Preeclampsia
Interventions: DRUG: ACE Inhibitors and Diuretics|DRUG: NIFEdipine ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Fascial Manipulation in Rotator's Cuff Surgery Patients
Status: COMPLETED
Conditions: Cuff Rotator Syndrome
Interventions: OTHER: fascial manipulation|OTHER: standard physiotherapies treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cabiralizumab in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor
Status: COMPLETED
Conditions: Pigmented Villonodular Synovitis|Tenosynovial Giant Cell Tumor
Interventions: BIOLOGICAL: FPA008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ACI-24 in Adults With Down Syndrome
Status: WITHDRAWN
Conditions: Down Syndrome
Interventions: BIOLOGICAL: ACI-24|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis
Status: RECRUITING
Conditions: Cat-Scratch Disease
Interventions: DRUG: gentamicin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter-Based Treatment of Cardiovascular Disease
Status: COMPLETED
Conditions: Obstructive Coronary Artery Disease|Obstructive Peripheral Artery Disease|Structural Heart Disease
Interventions: PROCEDURE: Percutaneous Transluminal Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Lettuce on Intestinal Water Content Through Magnetic Resonance Imaging of the Small Bowel
Status: COMPLETED
Conditions: Asymptomatic Conditions
Interventions: OTHER: Rhubarb|OTHER: Bread|OTHER: Lettuce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder
Status: WITHDRAWN
Conditions: Opioid-use Disorder|Suicidal Ideation
Interventions: DRUG: Buprenorphine/Naloxone 8/2 milligram (mg) Sublingual Film|DRUG: Morphine Sulfate 30 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MEdical Versus SUrgical Treatments of Rectal Endometriosis
Status: UNKNOWN
Conditions: Endometriosis
Interventions: DRUG: Triptoreline 11.25 i.v.; Estradiol 0.5% percutaneous gel;|PROCEDURE: rectal shaving; rectal disc excision; colorectal resection|DRUG: Cyproterone acetate 50 mg; estradiol 0.5% percutaneous|DRUG: Estradiol 0.5% percutaneous gel; Cyproterone acetate 50 mg oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aesthetic and Functional Outcomes of Eyelid Reconstruction After Excision of Periocular Tumors
Status: UNKNOWN
Conditions: Eyelid Defects|Periocular Tumors
Interventions: OTHER: Eyelid reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Octohydroaminoacridine Succinate Tablets in Patients With Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: Octohydroaminoacridine Succinate Tablets|DRUG: Octohydroaminoacridine Succinate Tablets|DRUG: Octohydroaminoacridine succinate Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison the Effectiveness of Mirror Therapy VS Music Therapy for Training in Post Stroke Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegia
Interventions: COMBINATION_PRODUCT: Mirror Therapy|OTHER: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Validation of a Medical Device, a Mobile Spectrofluorimeter, Measuring Skin Autofluorescence in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: mobile spectrofluorimeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Room Temperature Atomic Magnetrode System for Telemetry of Epileptic Seizures
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: OPM sensors|DEVICE: SQUID sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
Status: RECRUITING
Conditions: SARS-CoV-2 Virus|Severe Acute Respiratory Syndrome Coronavirus 2|COVID-19
Interventions: BIOLOGICAL: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 3 microgram dose|BIOLOGICAL: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 6 microgram dose|BIOLOGICAL: Bivalent BNT162b2 (original/Omicron BA.4/BA.5) 10 microgram dose|BIOLOGICAL: Variant-adapted BNT162b2 (Omicron XBB.1.5) Substudy A Ph 2/3 Selected Dose|BIOLOGICAL: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose|BIOLOGICAL: Variant-adapted BNT162b2 (Omicron XBB.1.5) 6 microgram dose|BIOLOGICAL: Variant-adapted BNT162b2 (Omicron XBB.1.5) 10 microgram dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Low-dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-negative Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and 177Lu-DOTA0-Tyr3-Octreotate for Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Nivolumab|RADIATION: 177Lu-DOTA0-Tyr3-Octreotate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19
Status: NOT_YET_RECRUITING
Conditions: Respiratory Infection Virus|Respiratory Failure
Interventions: DRUG: Sivelestat Sodium for Injection|DRUG: The Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Periodontal Tissues in Fixed Prostheses on Natural Teeth
Status: UNKNOWN
Conditions: Prosthetic Tissue Defect|Dental Prosthesis Complication|Dental Prosthesis Failure|Tissue Injury
Interventions: PROCEDURE: crown preparation|PROCEDURE: vertical preparation|PROCEDURE: horizontal preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Interest of a Therapeutic Follow-up of the Cytarabine in the Acute Myeloid Leukaemia: Is There Constitutional Biomarkers
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Blood sampling|GENETIC: Genetic analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Two Sub-occipital Techniques on Limited Mobility According to the Flexion-rotation Test
Status: COMPLETED
Conditions: Upper Cervical Spine Rotational Hypomobility
Interventions: OTHER: Manual technique of sub-occipital inhibition|OTHER: Self-treatment by way of Occipivot®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dysphagia in Cardiac Surgical Patients
Status: RECRUITING
Conditions: Cardiovascular Diseases|Dysphagia
Interventions: DIAGNOSTIC_TEST: Fiberoptic Endoscopic Evaluation of Swallowing|DIAGNOSTIC_TEST: Simultaneous FEES and Videofluoroscopy instrumental swallowing exam|DIAGNOSTIC_TEST: Videofluoroscopy instrumental swallowing exam (VFSS)|OTHER: Voluntary Cough Peak Expiratory Flow (PEF) Testing|OTHER: Reflex Cough Screen|OTHER: Lingual Pressure Testing|DIAGNOSTIC_TEST: Speech Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRI Guided HIFU for Palliation of Painful Skeletal Metastases in Children
Status: WITHDRAWN
Conditions: Bone Metastases|Pain
Interventions: DEVICE: MRI Guided High Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Resection for Small Rectal Neuroendocrine Tumors
Status: NOT_YET_RECRUITING
Conditions: Rectal Neuroendocrine Tumor
Interventions: PROCEDURE: mEMR-C procedure|PROCEDURE: ESD procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbiological Efficacy of Chloramine and Hyaluronic Acid Gels in Non-surgical Periodontitis Treatment
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planing|PROCEDURE: Scaling and root planing + "Perisolv" +"Hyadent BG" gels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Profile of IntRAvenous Lidocaine Use in Coelioscopic Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Bariatric Surgery
Interventions: BIOLOGICAL: Blood sampling|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pretherapeutic Paraaortic Lymphadenectomy in Women With Locally Advanced Cervical Cancer Versus Definitive Chemoradiotherapy
Status: WITHDRAWN
Conditions: Overall Survival Comparison Between the 2 Arms
Interventions: PROCEDURE: Surgery followed with chemoradiation|RADIATION: Standard chemoradiation|RADIATION: chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic Stimulation Paired With Body and Cortical Stimulation for Modulating Tinnitus
Status: WITHDRAWN
Conditions: Tinnitus
Interventions: DEVICE: noise sound stimulation (Tucker-Davis Technologies)|DEVICE: body electrical stimulation (Digitimer device)|DEVICE: transcranial magnetic stimulation (Magstim)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus
Status: RECRUITING
Conditions: Healthy Volunteers|Systemic Lupus Erythematosus (SLE)|Cutaneous Lupus Erythematosus (CLE)
Interventions: DRUG: Placebo|DRUG: KK4277
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer
Status: RECRUITING
Conditions: Stage III Pancreatic Cancer|Pancreatic Adenocarcinoma Non-resectable
Interventions: OTHER: Best Practice|OTHER: Dietary Intervention|OTHER: Medical Chart Review|OTHER: Medical Device Usage and Evaluation|OTHER: Nutritional Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes Mellitus|Overweight and Obesity
Interventions: DRUG: Tirzepatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence and Pharmacokinetic Study of Prurisol™ and Abacavir Sulfate in Healthy Volunteers
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Prurisol|DRUG: Ziagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Irinotecan Liposome and Bevacizumab for the Treatment of Platinum Resistant, Recurrent, or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Platinum-Resistant Fallopian Tube Carcinoma|Platinum-Resistant Ovarian Carcinoma|Platinum-Resistant Primary Peritoneal Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Refractory Fallopian Tube Carcinoma|Refractory Ovarian Carcinoma|Refractory Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Irinotecan Sucrosofate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Different Additives to Bupivacaine-fentanyl Mixture in Spinal Anesthesia for Cesarean Section
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: spinal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors
Status: TERMINATED
Conditions: Cancer|Melanoma|Solid Tumor|Squamous Cell Carcinoma of Head and Neck|Breast Cancer|Advanced Solid Tumor|Triple Negative Breast Cancer|Colorectal Carcinoma|Non-melanoma Skin Cancer|Liver Metastases
Interventions: BIOLOGICAL: ONCR-177|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pd-1 Antibody Combined Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasm|Uterine Cervical Cancer|Cervical Cancer
Interventions: DRUG: Cisplatin+Albumin-bound paclitaxel (1 cycle) and PD-1 monoclonal antibody+Cisplatin+Albumin-bound paclitaxel (2 cycles)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation (FES) Assisted Walking: Enhancement of Walking Function After Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Compex Motion Stimulator|DEVICE: Compex Motion Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of a Third Dose and Immune Persistence of BBIBP-Corv Vaccine in Elderly People With Chronic Bronchitis and COPD
Status: UNKNOWN
Conditions: COVID-19|Chronic Bronchitis|COPD
Interventions: BIOLOGICAL: Inactivated COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Five, Plus Nuts and Beans for Kidneys
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hypertension
Interventions: BEHAVIORAL: Coaching DASH group (C-DASH)|BEHAVIORAL: Self-Shopping DASH group (S-DASH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT