pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: TC-WYRE: TAXUS Express Stent vs. Cypher Stent - What's Your Real Life Experience?
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Stent and Cypher Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Non-surgical Treatment of Knee Osteoarthritis - a Comparison of Effects in 2200 Patients
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Paracetamol and nonsteroidal antiinflammatory drug (NSAID)|OTHER: Physiotherapy|DRUG: Cortisone Injection|OTHER: Others
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NasoVAX in Patients With Early Coronavirus Infectious Disease 2019 (COVID-19)
Status: TERMINATED
Conditions: Coronavirus Infection
Interventions: BIOLOGICAL: NasoVAX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling and Stretching in People With Fibromyalgia.
Status: COMPLETED
Conditions: Dry Needling|Stretch|Fibromyalgia
Interventions: OTHER: Dry needling on cervical trigger point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yasmin 20 Cycle Control - Yasmin 20 Versus Mercilon in Healthy Female Volunteers
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Yasmin 20|DRUG: Mercilon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab and Capecitabine in Treating Patients With Locally Advanced or Metastatic Triple Negative or Hormone-Refractory Breast Cancer That Cannot Be Removed by Surgery
Status: UNKNOWN
Conditions: Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage III Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Prevention|Human Immunodeficiency Virus (HIV)
Interventions: BIOLOGICAL: VRC-HIVRGP096-00-VP|OTHER: Alum Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of a Guided Bone Regeneration Membrane for the Treatment of Femoral Fractures
Status: UNKNOWN
Conditions: Proximal (Subtrochanteric)Femoral Fractures|Distal Femoral Fractures
Interventions: PROCEDURE: AMCA Bone Membrane.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Microcirculatory Characteristics of the Heart and Lung Meridians: A Study of COPD Patients and Healthy Adults
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Moxibustion|DEVICE: Laser doppler flowmetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities
Status: NOT_YET_RECRUITING
Conditions: Musculoskeletal Deformity|Musculoskeletal Abnormalities|Musculoskeletal Disorder
Interventions: PROCEDURE: Deformity correction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease
Status: COMPLETED
Conditions: Bone Avascular Necrosis|Sickle Cell Anemia
Interventions: PROCEDURE: Core decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Critical Limb Ischemia
Interventions: OTHER: BOLD-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Subcutaneous (SC) Bortezomib-Regimens for Patients With RR MM Failing Prior IV Bortezomib-Containing Regimens
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Subcutaneous bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Sanchi-Tongshu Capsule (Enteric Coated Pellets)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sanchi-Tongshu Capsule (Enteric coated pellets)|DRUG: Sanchi-Tongshu Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Vorinostat in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Nodal Marginal Zone Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Exercise Therapy Approach Biopsychosocial Questionnaire (BETY-BQ) in Patient With Temporomandibular Disorders
Status: RECRUITING
Conditions: Temporomandibular Disorder|Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Validity and reliability analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Induction Chemoterapy With Folfoxiri Plus Cetuxumab in Unresectable Colorectal Cancer Patient
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: folfoxiri+cetuximab+surgery+cetuximab|OTHER: folfoxiri+cetuximab+surgery+bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleural Malignant Mesothelioma
Interventions: BIOLOGICAL: Anetumab Ravtansine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye
Status: COMPLETED
Conditions: Chalazion|Dry Eye Syndromes
Interventions: DEVICE: Manual Mini System|DEVICE: iHeat Portable Warm Compress Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma
Status: RECRUITING
Conditions: Astrocytoma|Oligodendroglioma|Oligodendroastrocytoma
Interventions: RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-10516 in Patients With Advanced Clear Cell Renal Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: DRUG: HS-10516
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Extension Study to WA19926 (NCT01007435) of Tocilizumab in Participants With Early, Moderate to Severe Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Drug Eluting Peripheral Vascular Stent System in Superficial Femoral Artery Stenosis and /or Occlusion
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Superficial Femoral Artery Stenosis|Superficial Femoral Artery Occlusion
Interventions: DEVICE: Drug eluting peripheral vascular stent system|DEVICE: Nitinol Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interscalene Brachial Plexus Block Combined With Suprascapular Nerve Block
Status: COMPLETED
Conditions: Rotator Cuff Injury
Interventions: DEVICE: Ultrasound-guided ISB|DEVICE: Arthroscopy-guided SSNB|DRUG: Placebo|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transrectal Ultrasound (TRUS) in Finding Tumors During Robotic-Assisted Laparoscopic Surgery
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: ultrasound imaging|PROCEDURE: robot-assisted laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Icotinib Combined With Radiation Therapy For NSCLC Patients With Brain Metastases and EGFR Mutation
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Icotinib|RADIATION: WBRT or SRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging
Status: TERMINATED
Conditions: Amyloidosis
Interventions: DRUG: GSK2315698 (CPHPC)|DRUG: GSK2398852 (unlabeled anti-SAP mAb)|DRUG: 89Zr-GSK2398852 (89Zr-labeled anti-SAP mAb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety Study of Intravenously Administered UTTR1147A in Healthy Volunteers (HVs), Participants With Ulcerative Colitis (UC), and Participants With Crohn's Disease (CD)
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Placebo|DRUG: UTTR1147A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Based Induction Chemotherapy Followed by De-escalation Protocols in HPV-related OPSCC
Status: RECRUITING
Conditions: Oropharyngeal Carcinoma|Immune Checkpoint Inhibitor|De-escalation
Interventions: OTHER: Toxicities reduced treatment arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Well Different Doses of BI 3802876 Are Tolerated
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 3802876|DRUG: Placebo matching BI 3802876
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Functional Electrical Stimulation on Metaboreflex Activation in Healthy Individuals
Status: UNKNOWN
Conditions: Reduction of Blood Flow
Interventions: OTHER: Functional electric stimulation|OTHER: Isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPY-X: A Study to Assess the Feasibility of Using SPY Alone for Sentinel Node Localization for Melanoma or Breast Cancer
Status: COMPLETED
Conditions: Sentinel Lymph Node|Melanoma (Skin)|Breast Cancer
Interventions: DRUG: IC-Green KIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multidisciplinary Care Program to Secure mEdication Therapy for hematoLOgy Patients Receiving Injectable Anticancer Drugs
Status: COMPLETED
Conditions: Chemotherapy Effect|G-CHOP Chemotherapy|R-CHOP Chemotherapy
Interventions: OTHER: Assessment of patient satisfaction regarding tele-consultation|OTHER: Literacy questionnaire|OTHER: Collection of socio-demographic characteristics|OTHER: Assessment of patient knowledge on chemotherapy side effects and support medications|OTHER: Assessment of patient satisfaction on pharmaceutical follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Sequential Therapy of Camrelizumab Combined With Chemotherapy（Irinotecan Plus Platinum）and With Apatinib in Participants With Untreated Advanced Small Cell Lung Cancer（SCLC）
Status: UNKNOWN
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Camrelizumab，an engineered anti-PD-1 antibody|DRUG: Platinum|DRUG: Irinotecan|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronally Advanced Flap and PRF With or Without Demineralized Freeze-dried Bone Allograft in Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Coronally advanced flap and PRF with DFDBA|PROCEDURE: Coronally advanced flap and PRF without DFDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular Tachycardia
Status: TERMINATED
Conditions: Defibrillators, Implantable|Tachycardia, Ventricular
Interventions: PROCEDURE: Ablation|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bexarotene in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: AML|Acute Myeloid Leukemia
Interventions: DRUG: Bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Ectopic Bone Related Pain and Disability After Hip Replacement Surgery With Peri-Operative Ibuprofen
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Arthroplasty, Replacement, Hip|Arthritis, Rheumatoid
Interventions: DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: PET Scan in Patients With Lung and Esophageal Cancers That May Be Removed by Surgery
Status: COMPLETED
Conditions: Esophageal Cancer|Lung Cancer
Interventions: PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: The Omnibus Satiety Metric: Predicting Satiety in Humans Through Brain, Blood, and Subjective Data
Status: COMPLETED
Conditions: Satiation|Appetite|Behavior|Hunger
Interventions: DIETARY_SUPPLEMENT: Preload
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: GyroGlove Use in Essential Tremor Patients
Status: NOT_YET_RECRUITING
Conditions: Essential Tremor
Interventions: DEVICE: Placebo|DEVICE: GyroGlove
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rehabilitation in Subjects With Moderate Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Pulmonary rehabilitation|BEHAVIORAL: conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Children
Status: COMPLETED
Conditions: Gingivitis|Plaque
Interventions: DEVICE: GumChucks|DEVICE: String floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: State-wide Health Approach to Increase Reach and Effectiveness: Study 2
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Shape Up Rhode Island + Online weight loss program|BEHAVIORAL: Shape Up Rhode Island + Online weight loss program + Groups|BEHAVIORAL: Shape Up Rhode Island + Online weight loss + Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Jailed-balloon Technique in Coronary Bifurcation Lesion PCI
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Jailed-balloon technique|PROCEDURE: Jailed-wire technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Team Based Equity Conscious Telemedicine Approach to Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: OTHER: Feasibility Interview|BEHAVIORAL: Team Based Equity Conscious Telemedicine Hypertension Intervention|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PANFIRE-3 Trial: Assessing Safety and Efficacy of Irreversible Electroporation (IRE) + Nivolumab + CpG for Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DEVICE: Irreversible Electroporation (IRE)|DRUG: Nivolumab|DRUG: Toll-Like Receptor 9
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft and Hard Tissue Changes After Immediate Single-tooth Replacement
Status: COMPLETED
Conditions: Implant
Interventions: PROCEDURE: Immediate dental implant placement|PROCEDURE: Immediate dental implant placement with CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene-BPO Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry on Luma Vision's VERAFEYE System (ENLIgHT)
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Left Atrial Appendage Closure|Atrial Arrhythmia
Interventions: DEVICE: VERAFEYE System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Astrocytoma|Diffuse Brainstem Glioma|Glioblastoma Multiforme|High-grade Astrocytoma NOS|Fibrillary Astrocytoma|Low-Grade Astrocytoma, Nos|Pilocytic Astrocytoma|Choroid Plexus Carcinoma|CNS Primary Tumor, Nos|Atypical Teratoid/Rhabdoid Tumor|Medulloblastoma|Supratentorial Primitive Neuroectodermal Tumor|Ependymoma, NOS|Anaplastic Oligodendroglioma|Oligodendroglioma, Nos|CNS Germ Cell Tumor|Pineoblastoma|Diffuse Leptomeningeal Glioneuronal Tumor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Time Restricted Feeding on Nonalcoholic Fatty Liver Disease ( TREATY-FLD )：a 12-month Follow-up Study
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Time restricted feeding|BEHAVIORAL: Continuous Energy Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dabigatran Compared to Warfarin for 6 Month Treatment of Acute Symptomatic Venous Thromboembolism
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: dabigatran etexilate 150 mg|DRUG: warfarin (INR 2-3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Photoacoustic Imaging in the Course of Radiation Therapy of Malignant Head and Neck Tumors
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DEVICE: MSOT Acuity Echo device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevalence of Stuttering in Children With ADHD at Sohag University Hospital
Status: UNKNOWN
Conditions: ADHD Children With Stuttering
Interventions: DIAGNOSTIC_TEST: : Conners rating scale-Stanford-Binet Intelligence Scales- stuttering severity index third edition (SSI-3) .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: VEG113971: An Open-Label Study of the Effects of Ketoconazole or Esomeprazole on Pazopanib PK
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performance in Psychosis Risk
Status: NOT_YET_RECRUITING
Conditions: Psychosis
Interventions: DRUG: Levetiracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Outcomes Following Myocardial Revascularization: On and Off Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: Coronary artery bypass - on-pump|PROCEDURE: Coronary artery bypass - off-pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)
Status: COMPLETED
Conditions: Primary Myelofibrosis (PMF)|Post-polycythemia Vera (Post-PV) Myelofibrosis|Postessential Thrombocythemia (Post-ET) Myelofibrosis
Interventions: DRUG: MMB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0557 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0557-027)
Status: COMPLETED
Conditions: Paranoid Schizophrenia|Schizophrenia
Interventions: DRUG: MK0557|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Magnetic Resonance GUIDEd Insertion of Implantable Cardiac Defibrillator in Dilated CardioMyopathy
Status: NOT_YET_RECRUITING
Conditions: Dilated Cardiomyopathy|Left Ventricular Systolic Dysfunction|Fibrosis Myocardial
Interventions: DEVICE: ICD|DEVICE: ILR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Thymic
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Metagenomics and Metabolomics Analyses to Identify Potential Screening Biomarkers for Colorectal Polyps and Cancer in Chinese Population
Status: UNKNOWN
Conditions: Colorectal Cancer|Colorectal Polyp|Mass Screening|Gastrointestinal Microbiome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of CCH Treatment of Buttock and Thigh Cellulite in Adult Women
Status: TERMINATED
Conditions: Cellulite|Edematous Fibrosclerotic Panniculopathy (EFP)
Interventions: DRUG: EN3835
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systems Biology to Identify Biomarkers of Neonatal Vaccine Immunogenicity
Status: COMPLETED
Conditions: Newborn Vaccine Immunogenicity
Interventions: BIOLOGICAL: Hepatitis B vaccine (HBV)|BIOLOGICAL: Bacillus Calmette-Guérin (BCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Teneligliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain
Status: TERMINATED
Conditions: Breast Cancer|Lymphoma|Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of YiQiFuMai Injection as an Adjunctive Treatment for Sepsis
Status: NOT_YET_RECRUITING
Conditions: Sepsis
Interventions: DRUG: YiQiFuMai|DRUG: 0.9% Normal Saline 250ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flavors on Nicotine Reinforcement in Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: IV nicotine|DRUG: Menthol flavor|DRUG: green apple|DRUG: green apple and menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Eye Movement Desensitization and Reprocessing (EMDR) as a Treatment for Chronic Painful Diabetic Peripheral Neuropathy
Status: RECRUITING
Conditions: Neuropathic Pain|Diabetes Mellitus
Interventions: OTHER: Eye Movement Desensitization and Reprocessing|OTHER: Attention control phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Vitamin D in Primary Dysmenorrhoea
Status: COMPLETED
Conditions: Primary Dysmenorrhoea
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Vitamin E|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia
Status: TERMINATED
Conditions: Agitation|Dementia
Interventions: DRUG: BXCL501|DRUG: BXCL501|DRUG: Placebo film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Topotecan|DRUG: Amrubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Peg-interferon α-2a in Hepatitis B Patients Treated by Entecavir Without HBeAg Loss
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated DermaVir Immunizations in HIV-1 Infected Treatment-naïve Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: DermaVir|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Pain Reduction in CABG
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Dexmedetomidine Injectable Solution|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
Status: RECRUITING
Conditions: Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8
Interventions: OTHER: Best Practice|PROCEDURE: Laparoscopic Surgery|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DEVICE: Respiratory Muscle Training Device|PROCEDURE: Video-Assisted Thoracic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study for Treatment of Chronic Diabetic Foot Ulcers With the Investigational Allogeneic Cell Therapy Product, hOMSC200
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Foot|Diabetic Foot Ulcer|Diabetic Foot Ulcer Neuropathic
Interventions: BIOLOGICAL: hOMSC200|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Eperisone HCl in the Treatment of Acute Musculoskeletal Spasm Associated With Low Back Pain - A Double Blind, Randomised, Placebo Controlled Clinical Trial
Status: COMPLETED
Conditions: Muscle Spasm; Back Pain
Interventions: DRUG: Eperisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Longitudinal Prospective Outcomes Study of Laparoscopic Abdominal Wall Hernia Repair Using Symbotex™ Composite Mesh
Status: COMPLETED
Conditions: Grade I Ventral Hernia|Grade II Ventral Hernia
Interventions: DEVICE: Symbotex™ Composite Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebellar iTBS in Patients With Disorders of Consciousness
Status: UNKNOWN
Conditions: Disorder of Consciousness|Vegetative State|Minimally Conscious State
Interventions: DEVICE: iTBS stimulation|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization Versus Radioembolization in Treating Patients With Liver Cancer That Cannot Be Treated With Radiofrequency Ablation Or Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: RADIATION: yttrium Y 90 glass microspheres|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ELND005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth-Based Resistance Training Intervention for Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: OTHER: Baseline Measures|BEHAVIORAL: Strength-Training|OTHER: Mid-point Measures|OTHER: Post-Study Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Renal Denervation and pUlmonary Vein isolAtion With cryoabLation on Patients With Atrial Fibrillation and hypErtension
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation|Hypertension
Interventions: PROCEDURE: Renal artery cryoablation|PROCEDURE: Pulmonary vein cryoablation|PROCEDURE: Renal arteriography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Mirikizumab|DRUG: Mirikizumab|DRUG: Ustekinumab|DRUG: Ustekinumab|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Pharmacokinetic Parameters and Safety of NNG-TMAB (Trastuzumab) on Recurrent or Metastatic Breast Cancer Patients.
Status: COMPLETED
Conditions: Breast Cancer Metastatic|Breast Cancer Female|Breast Cancer Recurrent
Interventions: DRUG: Faceptor|DRUG: Herceptin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Japanese Healthy Male Volunteers To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-02341066
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-02341066|DRUG: PF-02341066|DRUG: PF-02341066
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Low-level Laser Therapy Versus Low-intensity Pulsed Ultrasound on Different Orthodontic Tooth Movements
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Low Level Laser Versus Low Intensity Pulsed Ultra Sound on Rate of Different Orthodontic Tooth Movement by Millimeter
Interventions: DEVICE: low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Magrolimab|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Magrolimab Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amla on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Amla|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer|Prostatic Neoplasms
Interventions: DRUG: 64Cu-SAR-bisPSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using 5 Minute Videos for Numeracy and Literacy Challenged Stroke Survivors to Improve Outcomes
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Video Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Plan and Stand Study: Reducing Sitting Time in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: Re-Patterning Sitting Time Group|BEHAVIORAL: Reducing Sitting Time Group|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thyroxine Treatment in Premature Infants With Intraventricular Hemorrhage
Status: WITHDRAWN
Conditions: Intraventricular Hemorrhage of Prematurity
Interventions: DRUG: Thyroxine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT-Guided Adaptive Radiation Therapy Combine With Anti-PD-1 Antibody Adjuvant Immunotherapy for Thoracic Cancer Patients
Status: UNKNOWN
Conditions: Thoracic Malignancies
Interventions: DRUG: IBI308
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automatic Oxygen Administration After Major Abdominal and Thoracic Surgery
Status: COMPLETED
Conditions: Major Thoracic and Abdominal Surgery
Interventions: DEVICE: FreeO2 v2.2 active|DEVICE: FreeO2 v2.2 with manual oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Closed Tracheal Aspiration Associated With Expiratory Pause in Pediatrics Randomized, Crossover Clinical Study
Status: UNKNOWN
Conditions: Respiratory Insufficiency in Children
Interventions: OTHER: with pause- without pause|OTHER: without pause-with pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Thrombopoietin In Patients With Severe and Very Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Anemia, Aplastic
Interventions: DRUG: rhTPO|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Susceptibility Testing Guided Therapy Versus Empirical Therapy for the First-line Helicobacter Pylori Eradication.
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Antimicrobial Susceptibility Testing
Interventions: DRUG: two sensitive antibiotics(amoxicillin, clarithromycin, metronidazole, tinidazole, levofloxacin, furazolidone and tetracycline)|DRUG: two antibiotics based on personal medication history(amoxicillin,clarithromycin,furazolidone)|DRUG: one proton pump inhibitor(PPI)|DRUG: Colloidal Bismuth Pectin|DRUG: two antibiotics for failed eradication(tetracyclin,furazolidone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma
Status: TERMINATED
Conditions: Plasmacytoma|Recurrent Multiple Myeloma|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Dexamethasone Sodium Phosphate|PROCEDURE: Echocardiography|DRUG: Lenalidomide|DRUG: Navtemadlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsule Endoscopy Versus Conservative Therapy for Obscure Gastrointestinal Bleeding
Status: WITHDRAWN
Conditions: Hemorrhage|Anemia
Interventions: DIETARY_SUPPLEMENT: Ferrous sulfate|DEVICE: Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of TPO Receptor Agonists in the Treatment of Elderly ITP Patients
Status: NOT_YET_RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: 2.5mg/d Hetrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enhancing Diabetes and Hypertension Self-Management Rural Appalachian Patients In Patient-Centered Medical Homes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Medication Adherence|BEHAVIORAL: Dietary Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution
Status: COMPLETED
Conditions: Normal Healthy Volunteers
Interventions: DRUG: Lofexidine (granules for reconstitution)|DRUG: LUCEMYRA (lofexidine) tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Coronary Artery Disease
Interventions: DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Off-the-shelf NK Cells + SCT for Myeloid Malignancies
Status: RECRUITING
Conditions: Myeloid Malignancies|Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Myeloid Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Filgrastim|DRUG: Melphalan|DRUG: Fludarabine phosphate|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Total Body Irradiation One Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Synbiotic on Cardiovascular and Bone Metabolism Markers in Transplanted Kidney Patients
Status: NOT_YET_RECRUITING
Conditions: Transplanted Kidney
Interventions: DIETARY_SUPPLEMENT: synbiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB30132A Against COVID-19 in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HFB30132A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Exposure to Umami Taste on Taste Perception, Hedonics, and Satiety
Status: COMPLETED
Conditions: Umami Taste Perception
Interventions: OTHER: Supplementation of diet with MSG|OTHER: No supplementation of diet with MSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase Ⅱ Clinical Study Trial of Felbinac Trometamol Injection in China
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Felbinac Trometamol Injection|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Kidney Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: RADIATION: stereotactic body radiation therapy|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
Status: RECRUITING
Conditions: Postoperative Pulmonary Complications
Interventions: OTHER: Preoperative Education|PROCEDURE: Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization|OTHER: Individualization of Neuromuscular Blockade|PROCEDURE: Postoperative Incentive Spirometry|BEHAVIORAL: Postoperative Ambulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endophthalmitis Vitrectomy Study (EVS)
Status: COMPLETED
Conditions: Endophthalmitis|Eye Infections
Interventions: DRUG: Intravitreal Antibiotics|PROCEDURE: Initial Pars Plana Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Manual vs Automated Anesthesia : Impact On The Incidence Of POCD
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DEVICE: closed-loop group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rivaroxaban Estimation With Warfarin in Atrial Fibrillation Patients With Coronary Stent Implantation Study (REWRAPS)
Status: COMPLETED
Conditions: Coronary Artery Disease|Atrial Fibrillation|Stroke|Fetal Blood Loss|Major Bleeding|All Cause Mortality
Interventions: DRUG: Rivaroxaban or Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Health Promotion Program for Educators (MBHP - Educa).
Status: COMPLETED
Conditions: Stress|Cognitive Impairment|Burnout Syndrome
Interventions: OTHER: MBHP-Educa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION