pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Interaction of Apelin and Angiotensin in the Human Forearm Circulation
Status: COMPLETED
Conditions: Heart Disease|Vasodilation
Interventions: DRUG: Angiotensin II|DRUG: Noradrenaline infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound Guided Diagnostic Lumbar Puncture in Neurology
Status: TERMINATED
Conditions: Lumbar Puncture
Interventions: PROCEDURE: Landmark-based lumbar puncture|PROCEDURE: Ultrasound-guided lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Prophylactic Antibiotics for Hysterosalpingography on Post Procedure Morbidity
Status: UNKNOWN
Conditions: Infertility, Female|Pelvic Inflammatory Disease
Interventions: DRUG: Doxycycline Capsule|DRUG: Multivitamins W/Iron Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial
Status: RECRUITING
Conditions: Lumbar Spine Degeneration|Lumbar Spine Instability|Lumbar Spondylolisthesis|Lumbar Spinal Stenosis
Interventions: PROCEDURE: Minimally invasive surgery|PROCEDURE: Percutaneous Spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Effect of Transfusion Strategies on Fatigability Levels After Hospital Discharge
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia|Red Blood Cell Transfusion|Fatigability|Fatigue|Physical Function
Interventions: OTHER: Red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramipril Versus Carvedilol in Duchenne and Becker Patients
Status: UNKNOWN
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy
Interventions: DRUG: carvedilol|DRUG: ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.
Status: UNKNOWN
Conditions: Leber Congenital Amaurosis 10|Blindness|Leber Congenital Amaurosis|Vision Disorders|Sensation Disorders|Neurologic Manifestations|Eye Diseases|Eye Disorders Congenital|Retinal Disease|Retinal Degeneration|Retinal Dystrophies
Interventions: DRUG: sepofarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Ketogenic Diet in Patients With Metastatic Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Ductal Adenocarcinoma
Interventions: OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examine the Preliminary Effect of an Evidence-Based Practice (EBP) Consultation Model on Staff Fidelity to EBP
Status: WITHDRAWN
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: TARGET|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes
Interventions: DRUG: Semaglutide|DRUG: DPP-4 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Ribavirin|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SNMC (Stronger Neo-Minophagen C ) for Acute Hepatitis Post Transarterial Chemoembolization Therapy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Stronger Neo-Minophagen C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How the Body Takes up and Tolerates Different Doses of BI 474121, and Whether it Makes a Difference if BI 474121 is Taken as a Tablet or a Drink.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 474121 tablet|DRUG: Placebo tablet|DRUG: BI 474121 oral solution|DRUG: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence and Drug - Drug Interaction Study of Metformin/Gliclazide in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin/Gliclazide Fixed Combination|DRUG: Metformin|DRUG: Gliclazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Dementia|Cognition Disorders in Old Age|Cognitive Decline|Cognitive Deterioration
Interventions: DEVICE: Combination of 40Hz light and cognitive therapy (ALZLIFE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients
Status: TERMINATED
Conditions: Obesity|Insulin Resistance|Metabolic Syndrome|Hepatitis C
Interventions: BEHAVIORAL: Dietary and Lifestyle modification educational sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Endothelial Dysfunction
Interventions: DRUG: Metformin, Ethinylestradiol 30µg-Drospirenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-wandering and Predictive Processes in Narcolepsy: a Putative Mechanism Through Covert REM Intrusions
Status: NOT_YET_RECRUITING
Conditions: Narcolepsy Type 1|Hypersomnolence|Idiopathic Hypersomnia
Interventions: BEHAVIORAL: ASRT|BEHAVIORAL: Questionnaires|DEVICE: Electrophysiological recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Pharmacodynamics/Pharmacokinetics After Repeated Dosing of D961H 10 mg and Omeprazole 10 mg in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Pharmacodynamics Study
Interventions: DRUG: D961H|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Place Controlled Study to Treat Recurrent Herpes Labialis.
Status: COMPLETED
Conditions: Recurrent Herpes Labialis
Interventions: DRUG: Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selenium and Vitamin E in Preventing Cancer Progression and Recurrence in Patients With Early-Stage Bladder Cancer
Status: UNKNOWN
Conditions: Bladder Cancer
Interventions: DRUG: selenium|DRUG: vitamin E|PROCEDURE: chemoprevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy and Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Intraocular Melanoma|Melanoma (Skin)
Interventions: BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Effects of Adjunctive Aripiprazole on the Brain in Treatment-Resistant Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Aripiprazole|DRUG: Placebo Capsule|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Pulmonary Doppler Signals in Patients With Systemic Sclerosis(SSc)
Status: WITHDRAWN
Conditions: Systemic Sclerosis|Pulmonary Hypertension
Interventions: RADIATION: Doppler ultrasound|DEVICE: Transthoracic Parametric Doppler (TPD) (Echosense Ltd., Haifa, Israel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors
Status: COMPLETED
Conditions: Acute Respiratory Failure|Post-Intensive Care Syndrome
Interventions: BEHAVIORAL: Mobile Critical Care Program|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minding the Baby Home Visiting: Program Evaluation
Status: COMPLETED
Conditions: Attachment|Child Maltreatment|Maternal Sensitivity|Infant Health
Interventions: BEHAVIORAL: Minding the Baby Home Visiting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)
Status: COMPLETED
Conditions: Compensated Cirrhosis|Nonalcoholic Steatohepatitis
Interventions: BIOLOGICAL: aldafermin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioavailability and Food Effect of JNJ-39439335 in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-39439335|DRUG: JNJ-39439335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT003 MDI|DRUG: PT005 MDI|DRUG: Placebo MDI|DRUG: Tiotropium bromide 18 μg (Spiriva Handihaler®)|DRUG: Formoterol Fumarate 12 μg (Foradil® Aerolizer®)|DRUG: PT001 MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: COMS One device|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion Device
Status: COMPLETED
Conditions: Prolapsed Lumbar Disc|Prolapsed Cervical Disc|Intervertebral Disc Degeneration|Spondylolisthesis, Grade 1|Intervertebral Disc Displacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Rituximab in Obtaining PCR (Polymerase Chain Reaction) Negative Leukapheresis Product in Patients With Relapsed Follicular Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-domain Improvements in High-TEchnology Rehabilitation Programs for Post-stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Technology-enhanced Rehabilitation|OTHER: Multidisciplinary Traditional Rehabiltiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotofunc - Non-traumatic Shoulder Instability and Total Rotator Cuff Function
Status: RECRUITING
Conditions: Shoulder Dislocation or Subluxation
Interventions: OTHER: Early Physiotherapist selected active exercises|OTHER: Delayed Physiotherapist selected active exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Heartburn|Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole Magnesium|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Family Programs for Improving Child and Family Health and Development
Status: ACTIVE_NOT_RECRUITING
Conditions: Behavior, Infant
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Sensitivity Intervention|BEHAVIORAL: Couples' Intervention|BEHAVIORAL: Sensitivity and Couples' Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA Vaccines
Status: COMPLETED
Conditions: Hemorrhagic Fever With Renal Syndrome
Interventions: BIOLOGICAL: Vaccine/device combination for prevention of HFRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of XSurge Supplementation on Biomarkers and Performance From High Intensity Resistance Exercise
Status: COMPLETED
Conditions: Exercise Performance Recovery
Interventions: DIETARY_SUPPLEMENT: XSurge|OTHER: Placebo: Microcrystalline Cellulose|OTHER: Control: No supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient-centered Approaches to Provider and Adolescent Reproductive Health Communication and Shared Decision-making
Status: TERMINATED
Conditions: Reproductive Behavior
Interventions: BEHAVIORAL: An electronic self-administered pre-visit planning tool.|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMD
Status: ACTIVE_NOT_RECRUITING
Conditions: Geographic Atrophy Secondary to Age-related Macular Degeneration
Interventions: DRUG: PEGCETACOPLAN (APL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine
Status: COMPLETED
Conditions: Cocaine Addiction|Cocaine Abuse|Cocaine Dependence|Substance Abuse
Interventions: DRUG: Placebo|DRUG: Doxazosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Omacetaxine and Low Dose Cytarabine in Older Patients With Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Omacetaxine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vandetanib, Oxaliplatin, and Docetaxel in Advanced Cancer of the Esophagus or Gastroesophageal Junction
Status: TERMINATED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer
Interventions: DRUG: docetaxel|DRUG: oxaliplatin|DRUG: vandetanib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response
Status: COMPLETED
Conditions: Bloodstream Infections
Interventions: DRUG: Meropenem|DRUG: Piperacillin-tazobactam combination product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize Pharmacokinetics of Tiotropium + Olodaterol Fixed-dose Combination in Japanese Patients With COPD.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium (high dose) + Olodaterol|DRUG: Tiotropium (low dose) + Olodaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UPTAKE: Using Personalized Risk and Digital Tools to Guide Transitions Following Acute Kidney Events
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Risk-guided transition of care intervention delivered through an integrated digital health strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proprioceptive Function, Postural Stability & Clinical Outcome After Stump Preserving Anterior Cruciate Ligament Reconstruction Surgery
Status: UNKNOWN
Conditions: Ruptured Anterior Cruciate Ligament|Partial Tear Ligament
Interventions: OTHER: conventional ACL rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Auryxia (Ferric Citrate) Therapy for In-Center and Home Dialysis Participants
Status: COMPLETED
Conditions: Hyperphosphatemia|Anemia, Iron Deficiency|Renal Insufficiency
Interventions: DRUG: Ferric Citrate 1 gram Oral Tablet|DRUG: Standard of care phosphate-lowering therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Underlying Mechanisms of Sphenopalatine Ganglion Acupuncture for Seasonal Allergic Rhinitis
Status: UNKNOWN
Conditions: Seasonal Allergic Rhinitis
Interventions: PROCEDURE: SPA acupuncture|PROCEDURE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis
Status: COMPLETED
Conditions: Renal Dialysis|Pharmacokinetics
Interventions: DRUG: PD-0332334
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CAR-NK-CD19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Reported Outcomes Study Using Electronic Monitoring System for Advanced or Metastatic Solid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Lung Cancer|Colorectal Cancer|Liver Cancer|Stomach Cancer|Endometrial Cancer|Ovarian Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: OTHER: e-PRO monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Formoterol/Fluticasone and Salmeterol/Fluticasone in Patients With Moderate-to-severe COPD
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Combination Fluticasone /Formoterol 12/250 μg|DRUG: Seretide Diskus (salmeterol/fluticasone) 50/250 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DRUG: paclitaxel|DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Dosages and Exercise Adherence With Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: High Dosage Home Exercise Training|OTHER: Standard Dosage Home Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence and Perspiration While Wearing Lower Limb Prostheses
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Extremity Amputation
Interventions: DEVICE: Dynamic Air Exchange - Rising Edge Design (DAE-RED)|DEVICE: Perforated elastomeric liner|DEVICE: As-prescribed prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kintampo Trial of Combination Therapy for Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: artesunate-amodiaquine|DRUG: coartem|DRUG: artesunate-lapdap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Irinotecan Combination Regimen for Second-line Treatment of Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Gastric Cancer
Interventions: DRUG: Irinotecan Hydrochloride Liposome Injection；Paclitaxel For Injection (Albumin Bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis
Status: COMPLETED
Conditions: Malignant Solid Neoplasm
Interventions: PROCEDURE: Advanced Magnetic Resonance Imaging|PROCEDURE: Conventional Magnetic Resonance Imaging|DRUG: Gadolinium-Chelate|DRUG: Iopamidol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2B Clinical Study of Chondrogen for Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Chondrogen|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Primary Amyloid Cardiomyopathy
Status: RECRUITING
Conditions: Amyloidosis, Primary|Cardiomyopathy
Interventions: RADIATION: F-18 florbetapir/C-11 acetate PET|DEVICE: MRI|RADIATION: N-13 ammonia PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lavender Aromatherapy for Anxiety During Urodynamics
Status: COMPLETED
Conditions: Anxiety|Pain
Interventions: OTHER: Lavandula angustifolia essential oil (Aura Cacia)|OTHER: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: mavacamten|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CSII followed by Lina+MET|DRUG: CSII followed by Lina|DRUG: CSII followed by MET|DRUG: CSII alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAX
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: ChimeriVax™-JE|BIOLOGICAL: JE-VAX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Marginal and Internal Fit of High Performance Polymer PEEK Endocrown Using Two Preparation Designs
Status: RECRUITING
Conditions: Endodontically Treated Molar|Marginal Fit|Internal Fit
Interventions: OTHER: Bevel marginal design endocrown for endodontically treated teeth|OTHER: Butt marginal design endocrown for endodontically treated teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Influence of Gravity on the Perception of Egocentric Distance (Blindpulling)
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: OTHER: perceived egocentric distance (PED) measurements|OTHER: Parabolic flight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
Status: COMPLETED
Conditions: Ovulation|Luteal Development
Interventions: DRUG: Celebrex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: StriveWeekly: Self-Guided Online Intervention for Anxiety, Depression, and Stress in University Students
Status: COMPLETED
Conditions: Anxiety|Depressive Symptoms|Stress, Psychological
Interventions: BEHAVIORAL: StriveWeekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Postoperative Chemoradiotherapy With or Without Consolidation Chemotherapy for Cervical Cancer Patients
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: paclitaxel|DRUG: cisplatin|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go App
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle B+ Thalassemia|Sickle Beta Zero Thalassemia|Sickle Cell Hemoglobin C
Interventions: OTHER: HU-Go app
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact on the Oxidative Stress of the Different Analogues of Insulin in People With Type 1 Diabetes. (Ineox Study)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Toujeo SoloStar|DRUG: Tresiba|DRUG: Humalog Kwikpen|DRUG: NovoRapid|DRUG: Apidra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MISOBEST - Orally Misoprostol Solution (Cytotec®) Versus Orally Misoprostol as a Tablet (Angusta®) for Induction of Labor
Status: COMPLETED
Conditions: Induced Vaginal Delivery
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Obesity|Hyperlipidemia|Insulin Resistance|Metabolic Syndrome X
Interventions: BEHAVIORAL: Resistance Training|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Combo|BEHAVIORAL: Continued Sedentary lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Accell Evo3™ Demineralized Bone Matrix in Instrumented Lumbar Spine Fusion
Status: COMPLETED
Conditions: Degenerative Changes|Stenosis|Spondylosis
Interventions: PROCEDURE: Posterolateral Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lactoferrin Versus Ferrous Fumarate for Treatment of Mild to Moderate Iron Deficiency Anemia During Pregnancy
Status: UNKNOWN
Conditions: Iron Deficiency Anemia of Pregnancy
Interventions: DRUG: Lactoferrin and ferrous fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Knowledge for Spanish-speaking Parents
Status: COMPLETED
Conditions: Obesity|Dental Caries
Interventions: OTHER: Kiosk|OTHER: paper|OTHER: Kiosk PLUS paper|OTHER: Kiosk PLUS web
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Safety and Efficacy of Psilocybin in Participants With Type 2 Bipolar Disorder (BP-II) Depression.
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Pre-incisional wound infiltration|PROCEDURE: Laparoscope to place TAP block with liposomal bupivacaine|DRUG: Liposomal bupivacaine|DRUG: Bupivacaine|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of SHR-2002 + SHR-1316 in Patients With Advanced Malignant Tumors
Status: COMPLETED
Conditions: Advanced Malignant Tumors
Interventions: DRUG: SHR-2002 and SHR-1316
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|OTHER: Chemosensitivity Assay|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation Trial to Evaluate a Population Health Combination Intervention to Meet HIV Testing, Linkage, and Viral Suppression Goals in Alabama
Status: RECRUITING
Conditions: HIV|HIV Linkage to Care|HIV Testing|HIV Treatment
Interventions: OTHER: COAST-AL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Remdesivir|DRUG: Lopinavir/ Ritonavir and Remdesivir combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention For Families Experiencing Homelessness: A Randomized Trial Comparing Two Parenting Programs
Status: COMPLETED
Conditions: Behavior Problem|Parenting
Interventions: BEHAVIORAL: Parent Child Interaction Therapy|BEHAVIORAL: Child Parent Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Camrelizumab|DRUG: Chemotherapy|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab + Taxotere With Low Dose Fractionated Radiation for Head and Neck Carcinoma
Status: TERMINATED
Conditions: Squamous Cell Carcinoma|Head and Neck Cancer|Recurrent Disease
Interventions: DRUG: Erbitux|DRUG: Taxotere|RADIATION: Low Dose Fractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01) Phase III
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Pandemic
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 fusion protein vaccine (V-01)|OTHER: Blank Preparation of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Management of the Idiopathic Overactive Bladder With Botulinum Toxin: Systematic Review
Status: UNKNOWN
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: Intradetrusor Injection of Type-A Botulinum Toxin|OTHER: Other interventions analyzed according to protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating 111In Panitumumab for Nodal Staging in Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Panitumumab|OTHER: Indium In 111 Panitumumab|PROCEDURE: Single Photon Emission Computed Tomography|PROCEDURE: Computed Tomography|PROCEDURE: Surgical Procedure|OTHER: Imaging agent|PROCEDURE: Intraoperative Imaging|PROCEDURE: Near Infrared Imaging|PROCEDURE: Electrocardiography|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Apathy in Alzheimer's Disease With Modafinil
Status: COMPLETED
Conditions: Apathy|Alzheimer's Disease
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory and Metabolic Responses to Long-term Dietary Supplementation With Anthocyanin-rich Blend
Status: ACTIVE_NOT_RECRUITING
Conditions: Anthocyanins
Interventions: DIETARY_SUPPLEMENT: ACRB|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose Escalation Study of Valortim® (MDX-1303) Administered Intravenously (IV) in Healthy, Normal Subjects
Status: COMPLETED
Conditions: Anthrax
Interventions: DRUG: Normal Saline for Injection|BIOLOGICAL: MDX1303
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PAT-1251 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis
Status: WITHDRAWN
Conditions: Myelofibrosis Transformation in Essential Thrombocythemia|Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase|Primary Myelofibrosis
Interventions: DRUG: LOXL2 Inhibitor PAT-1251|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 123-I-MIP-1072|DRUG: 111-In capromab pendetide|DRUG: 123-I-MIP-1072
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: -Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans.
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: GPR 119 agonist, 2-oleyl glycerol|DIETARY_SUPPLEMENT: Oleic acid|DIETARY_SUPPLEMENT: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Nasal Changes Affected by Different Alar Base Suture Techniques After Maxillary LeFort I Osteotomy
Status: COMPLETED
Conditions: Conditions in T74.31 or T76.31
Interventions: PROCEDURE: conventional alar base cinch|PROCEDURE: modified alar base cinch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Excimer Light and Topical Steroid in Treatment of Alopecia Areata
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: COMBINATION_PRODUCT: topical steroid and 308nm-Excimer light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Pharmacokinetics and Safety of TQD3524 for Injection in Renal Impairment Subjects
Status: NOT_YET_RECRUITING
Conditions: Multi-resistant Gram-negative Bacteria Cause Infection
Interventions: DRUG: TQD3524|DRUG: TQD3524|DRUG: TQD3524|DRUG: TQD3524|DRUG: TQD3524|DRUG: TQD3524
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
Status: COMPLETED
Conditions: Drug Use Disorders|Illicit Drug Use|Alcohol-Related Disorders
Interventions: BEHAVIORAL: Health Coaching|BEHAVIORAL: Practice Facilitation|BEHAVIORAL: Standard Implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Atrio-ventricular Optimization With His Bundle Pacing on Treatment of Atrio-ventricular Dromotropathy
Status: COMPLETED
Conditions: Atrioventricular Block|Atrioventricular Dyssynchrony
Interventions: DEVICE: His bundle pacing, AV optimized|DEVICE: Backup VVI pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rethinking Pulmonary Rehabilitation
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: pulmonary tele-rehabilitation (PTR)|BEHAVIORAL: home-based pulmonary rehabilitation (HPR)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Silk Scaffold Surgical Incision Dressing
Status: COMPLETED
Conditions: Surgical Incision
Interventions: DEVICE: Dermabond Prineo Skin Closure System|DEVICE: silk|DEVICE: 3M Steri-Strip
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nimotuzumab With Radiotherapy in the Treatment of Anal Canal Cancers
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of Anal Canal
Interventions: DRUG: Nimotuzumab|RADIATION: Intensity Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT-GLOBAL)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: 177Lu-TLX591|DRUG: Enzalutamide|DRUG: Abiraterone|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Consequences of T-bet Expression in Flu-specific Memory B Cells After Live Attenuated Influenza Vaccine (LAIV)
Status: RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Treatment Group Live Attenuated Flu Vaccine (LAIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cue2Walk, Cost-effectiveness of Automated Freezing Detection and Provision of External Cues in Comparison to Usual Care in People With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Cue2Walk|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delirium Prevention in Patients From the Intensive Care Unit (DELA)
Status: UNKNOWN
Conditions: Hypoactive Delirium|Hyperactive Delirium|Delirium of Mixed Origin
Interventions: BEHAVIORAL: Delirium prevention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase IV Study of Concomitant Administration of the sIPV and HepA
Status: NOT_YET_RECRUITING
Conditions: Polio|Hepatitis A
Interventions: BIOLOGICAL: sIPV (booster dose at 18 months of age)|BIOLOGICAL: HepA-L|BIOLOGICAL: HepA-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Epidermal Growth Factor-containing Ointment on the Solar Lentigines
Status: COMPLETED
Conditions: Epidermal Growth Factor|Nd-yttrium Aluminum Garnet Laser|Hyperpigmentation|Post Inflammatory Hyperpigmentation
Interventions: DRUG: epidermal growth factor (EGF)-containing ointment|DRUG: Vehicle ointment|PROCEDURE: Q-swithced (QS) 532-nm Nd:yttrium aluminum garnet (YAG) laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Camel Milk on Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon, Ribavirin, camel milk|DRUG: Peginterferon, Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies
Status: TERMINATED
Conditions: Metastatic Cancer Pancreas
Interventions: DRUG: PF-03084014|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: PF-03084014|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual SSTR2 and Integrin αvβ3 Targeting PET/CT Imaging
Status: UNKNOWN
Conditions: Lung Cancer|Neuroendocrine Neoplasm
Interventions: DRUG: 68Ga-NOTA-3P-TATE-RGD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Differentiated Thyroid Cancer: is There a Need for Radioiodine Ablation in Low Risk Patients?
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Risk Differentiated Thyroid Cancer
Interventions: DRUG: rhTSH stimulation|DRUG: I131|OTHER: Follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PEP Buddy Impact on Breathing, Exercise, and Sleep Quality in COPD Patients
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: PEP Buddy|OTHER: aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT Study on Granulocyte Colony-stimulating Factor(G-CSF) Treatment of Hepatic Failure
Status: UNKNOWN
Conditions: Liver Failure|Hepatitis B|Alcoholic Liver Disease
Interventions: DRUG: Granulocyte colony-stimulating factor|DRUG: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT