pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Orthoapnea NOA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partnering Physical and Emotional Fitness: Improving Cardiac Recovery With Training in Emotion Regulation
Status: COMPLETED
Conditions: Cardiac Disease|Myocardial Infarction
Interventions: OTHER: RENEwS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
Status: TERMINATED
Conditions: Pain|Bone Neoplasm|Neoplasm Metastasis
Interventions: DRUG: ibandronate [Bondronat]|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease
Status: COMPLETED
Conditions: Phase 1 Sickle Cell
Interventions: DRUG: PDE9i|DRUG: PDE9i|DRUG: placebo for PDE9i|DRUG: PDE9i
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telemetric Arrhythmia and Syncope Diagnosis - Evaluation of Arrhythmia Treatment Efficacy
Status: UNKNOWN
Conditions: Atrial Fibrillation|Arrhythmias, Cardiac
Interventions: DEVICE: Prolonged telemetric Full Disclosure ECG recording.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Self-Affirmation Intervention to Promote Hearing Aid Use
Status: UNKNOWN
Conditions: Hearing Loss, Functional
Interventions: BEHAVIORAL: Self-Affirmation Exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Trial of Miglitol in Type 2 Diabetic Patients Treated With Biguanide
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Miglitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tissue Oxygenation Measurement Using Multimodal Devices
Status: COMPLETED
Conditions: Oxygen Saturation
Interventions: DEVICE: Clarifi Modulum|DEVICE: Perimed PeriFlux 5000|DEVICE: Apple Watch Oxygen Sensor|DEVICE: Innovo iP 900AP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Novel E-health Platform
Status: TERMINATED
Conditions: Aging Well|Decision Making|Illness, Critical
Interventions: OTHER: Serious illness medical planning plus the novel e-health platform (PWG 2.0)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Docetaxel Versus Docetaxel Plus Cisplatin Versus Docetaxel Plus S-1 as Second-line Chemotherapy in Metastatic Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: docetaxel|DRUG: docetaxel, cisplatin|DRUG: docetaxel, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefits and Risks of Different Menopausal Hormone Replacement Therapy Regimes in the Treatment of Menopause Syndrome
Status: UNKNOWN
Conditions: Menopause Syndrome
Interventions: DRUG: CEE 0.625 mg/MP 100mg|DRUG: CEE 0.3 mg/MP 100mg|DRUG: CEE 0.625mg/dydrogesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Primordial Dwarfisms: Diagnosis, Identification of the Molecular Basis of Seckel Syndrome and Microcephalic Osteodysplastic Primordial Dwarfism Type II
Status: COMPLETED
Conditions: Microcephalic Osteodysplastic Primordial Dwarfism Type II|Seckel Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Busulfan|DRUG: Fludarabine|DRUG: Clofarabine|RADIATION: Total Body Irradiation (TBI)|DRUG: Thymoglobulin|BIOLOGICAL: Stem Cell Infusion|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate mofetil|DRUG: Decitabine|DRUG: Cytarabine|DRUG: Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With Tumor Specific Mutated VHL Peptides in Adult Cancer Patients With Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: von Hippel-Lindau peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uterine Artery Embolization(UAE) Versus High-Intensity-Focused-Ultrasound(HIFU) for Treatment of Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: PROCEDURE: UAE|PROCEDURE: HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Point-of-Care (POC), SARS-CoV-2 (COVID-19) IgG Antibody Test in Fingerstick Whole Blood
Status: COMPLETED
Conditions: SARS-Cov-2, Covid19
Interventions: DIAGNOSTIC_TEST: POC SARS-Cov-2 IgG Antibody test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Once Daily Calcium and Vitamin D Fortified Food Product to Improve Bone Microarchitecture
Status: COMPLETED
Conditions: Bone Alteration|Dietary Modification
Interventions: DIETARY_SUPPLEMENT: Calcium/Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PET Detection of CCR2 in Human Atherosclerosis
Status: RECRUITING
Conditions: Carotid Atherosclerosis
Interventions: DRUG: Group 1-64CU-DOTA-ECL1i (radioactive imaging medicine)|DRUG: Group 2 64CU-DOTA-ECL1i (radioactive imaging medicine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Screening Donors, Fecal Microbiota Transplant Program in Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis Flare
Interventions: OTHER: Fecal Microbiota transplant (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Safety and Tolerability of the New Monoclonal Humanized Antibody CaCP29
Status: COMPLETED
Conditions: Drug Safety
Interventions: BIOLOGICAL: CaCP29, a humanized monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Trial of the Effect of Motavizumab Prophylaxis on Reduction of Serious Early Childhood Wheezing in Infants
Status: WITHDRAWN
Conditions: Wheezing
Interventions: BIOLOGICAL: Motavizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
Status: RECRUITING
Conditions: Sarcoma|Bone Sarcoma|Soft Tissue Sarcoma
Interventions: OTHER: referral to the Memorial Sloan-Kettering Cancer Center (MSK) Department of Psychiatry and Behavioral Sciences.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dermatosis Papulosa Nigra
Status: COMPLETED
Conditions: Facial Dermatoses|Seborrheic Keratoses
Interventions: DEVICE: Pulsed dye laser|PROCEDURE: Curettage|PROCEDURE: Electrodesiccation|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Chemo in Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma (Eastern Cooperative Thoracic Oncology Projects 2004, ECTOP-2004)
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Blood and Urine Concentration and the Safety and Tolerability of Increasing Repeated Doses of Mirabegron (YM178) OCAS in Healthy Young and Elderly Males and Healthy Young and Elderly Females
Status: COMPLETED
Conditions: Pharmacokinetics|Healthy Subjects
Interventions: DRUG: mirabegron OCAS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Self-Administered Lidocaine Gel for Pain Management With IUD Insertion
Status: COMPLETED
Conditions: IUD Insertion
Interventions: DRUG: Vaginal 2% Lidocaine|DRUG: Surgical Lubricant Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Core Stabilization Training With and Without Pressure Biofeedback in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: pressure biofeedback|OTHER: core stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Traumatic Brain Injury.
Status: COMPLETED
Conditions: Craniocerebral Trauma|Traumatic Brain Injury|"Rehabilitation"
Interventions: BEHAVIORAL: body weight support treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spanish Registry of Mohs Surgery
Status: COMPLETED
Conditions: Skin Neoplasms|Carcinoma, Basal Cell|Carcinoma, Squamous Cell|Dermatofibrosarcoma|Melanoma|Histiocytoma, Malignant Fibrous|Neoplasms, Adnexal and Skin Appendage
Interventions: PROCEDURE: Mohs surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Recombinant Factor VIIa in Acute Intracerebral Haemorrhage
Status: COMPLETED
Conditions: Acquired Bleeding Disorder|Intracerebral Haemorrhage
Interventions: DRUG: activated recombinant human factor VII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 60732 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 60732|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of the SmartDrive on Mobility, Activity and Shoulder Pain Among People With SCI Using Manual Wheelchairs
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: SmartDrive Mx2+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)
Status: NOT_YET_RECRUITING
Conditions: Tricuspid Regurgitation (TR)
Interventions: DEVICE: Transcatheter Tricuspid Valve Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Vaccination: Evaluation of Reminder Prompts for Doses 2 & 3
Status: COMPLETED
Conditions: Human Papilloma Virus Infection Type 11|Human Papilloma Virus Infection Type 16|Human Papilloma Virus Infection Type 18|Human Papilloma Virus Infection Type 6|Cervical Cancer|Genital Warts|Oropharyngeal Cancer
Interventions: BEHAVIORAL: Simple Reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD
Status: ENROLLING_BY_INVITATION
Conditions: Neovascular Age-Related Macular Degeneration (nAMD)|Gene Therapy|AMD|Wet AMD|wAMD|nAMD
Interventions: OTHER: No intervention.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Healthy Volunteers to Prove That Two Different Formulations of Rotigotine Patches Deliver Equivalent Drug Amount to the Body
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Rotigotine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy
Status: RECRUITING
Conditions: Sickle Cell Retinopathy|Sickle Cell Disease|Sickle Cell SC Disease|Sickle Cell-SS Disease
Interventions: OTHER: Collection of venous blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: Single-pulse Transcranial Magnetic Stimulation (TMS)|DEVICE: Paired-pulse Transcranial Magnetic Stimulation (ppTMS)|DEVICE: Low-frequency Repetitive Transcranial Magnetic Stimulation (rTMS)|DEVICE: Sham Motor Cortex Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Maintenance (vs. Change) of Critical Attitudes Towards Psychotherapy
Status: UNKNOWN
Conditions: Negative Therapy Expectation
Interventions: BEHAVIORAL: video intervention (therapy expectation violation)|BEHAVIORAL: video intervention (symptoms+ expectation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section|Infection
Interventions: DRUG: Cefazolin (Timing of Antibiotic Prophylaxis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluid Responsiveness in Post-cardiac Surgery
Status: RECRUITING
Conditions: Fluid Overload|Cardiac Surgery|Postoperative Complications
Interventions: PROCEDURE: Combined end-expiratory occlusion and end-inspiratory occlusion test|PROCEDURE: Tidal volume challenge test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: decitabine (5-aza-2'deoxycytidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma)
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Sapropterin dihydrochloride tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA
Status: COMPLETED
Conditions: Skin Diseases, Infectious|Staphylococcal Skin Infections
Interventions: DRUG: Ceftaroline|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Bleximenib|DRUG: Venetoclax (VEN)|DRUG: Azacitidine (AZA)|DRUG: Cytarabine|DRUG: Daunorubicin or Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASIA-Mesh: a Pilot Study for Diagnostics and Treatment on ASIA Syndrome Caused by Polypropylene Mesh Implantation
Status: RECRUITING
Conditions: Autoimmunity|Inguinal Hernia|Stress Urinary Incontinence|Pelvic Organ Prolapse|Implant Complication|Systemic Autoimmune Disease
Interventions: DIAGNOSTIC_TEST: mesh allergy test|DIAGNOSTIC_TEST: blood tests|PROCEDURE: Mesh removal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Macroporous Polytetrafluoroethylene Mesh in Laparoscopic Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Totally Extraperitoneal laparoscopic inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705 and GW642444|DRUG: GW642444|DRUG: GSK233705|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Czech Pharmaco-epidemiological Study on Disease Modifying Drugs
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolimod, ponesimod, rituximab, ocrelizumab, ofatumumab, natalizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase Ⅰ Clinical Study of Anti-CD52 Monoclonal Antibody in NHL and T-PLL
Status: UNKNOWN
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, T-Cell
Interventions: BIOLOGICAL: Recombinant Humanized Anti-CD52 Monoclonal Antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Teaching Methods of Pelvic Floor Muscle Contraction in Women
Status: NOT_YET_RECRUITING
Conditions: Pelvic Floor Muscle Weakness
Interventions: OTHER: group1, group2, group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a New Toothpaste for the Removal of Dental Calculus.
Status: COMPLETED
Conditions: Calculus, Dental|Periodontal Diseases|Periodontal Inflammation
Interventions: OTHER: Bio-descaling D-Tart toothpaste|OTHER: Crest® toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of the Effect of Modified Colonoscopy Bowel Preparation Program on Intestinal Cleaning, Examination and Disease in Patients With Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Polyethylene Glycols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Postoperative INTELLiVENT-ASV Ventilation
Status: COMPLETED
Conditions: Ventilators, Mechanical|Intensive Care Units|Postoperative Care
Interventions: DEVICE: INTELLiVENT-ASV|DEVICE: Conventional modes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol Versus Calcitriol for Efficacy and Safety in Stage 3/4 Chronic Kidney Disease (CKD) With Secondary Hyperparathyroidism (SHPT)
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Paricalcitol|DRUG: Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptation of Locomotor Activity in Patients Suffering From Hip OA - Analysis of This Adaptation as a Prognostic Criterion for Future Disease Progression
Status: UNKNOWN
Conditions: Primary Hip Osteoarthritis
Interventions: PROCEDURE: Evaluation of the balance of force platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: WOUNDCHEK™ Protease Status Point of Care (POC) Diagnostic Test
Status: UNKNOWN
Conditions: Venus Leg Ulcers
Interventions: DEVICE: Promogran|DEVICE: Coban 2 layer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anxiety Reduction in Type 2 Diabetes Through Breathing ExercisesPatients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Type 2 Diabetes Treated With Insulin
Interventions: BEHAVIORAL: BREATH technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Status: COMPLETED
Conditions: Complication of Renal Dialysis|End Stage Renal Disease|End Stage Kidney Disease|ESRD|Chronic Kidney Failure|Complication of Hemodialysis|Vascular Access Complication|Arteriovenous Fistula
Interventions: DRUG: Sirolimus|PROCEDURE: AV Fistula Surgery|DEVICE: Sirolimus-eluting Collagen Implant (SeCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy Test of Nutri-PEITC Jelly in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Quality of Life|Nutrition Related Cancer
Interventions: DIETARY_SUPPLEMENT: Nutri-jelly with PEITC|DIETARY_SUPPLEMENT: Nutri-jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
Status: RECRUITING
Conditions: Neuroblastoma|Refractory Neuroblastoma|Relapsed Neuroblastoma|Relapsed Osteosarcoma|Refractory Osteosarcoma
Interventions: COMBINATION_PRODUCT: Ex Vivo Expanded Allogeneic γδ T Cells in Combination with Dinutuximab, Temozolomide, Irinotecan and Zoledronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Bimekizumab|DRUG: Adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women Engaging in Quitting Smoking Together (WE QUIT)
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Distress Tolerance Treatment for Weight Concern (DT-W)|BEHAVIORAL: Health Education (HE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COPD Treatment by Transplantation of Autologous Bronchial Basal Cells
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BIOLOGICAL: Autologuos transplantation of bronchial basal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heated Mittens for Patients With Hand Osteoarthritis
Status: COMPLETED
Conditions: Hand Osteoarthritis
Interventions: DEVICE: activated mittens|DEVICE: deactivated mittens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice
Status: SUSPENDED
Conditions: Hyperbilirubinemia, Neonatal|Jaundice, Neonatal
Interventions: PROCEDURE: Delayed cord clamping|PROCEDURE: Early cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer
Status: RECRUITING
Conditions: Stage III Prostate Cancer AJCC v8|Stage IIIA Prostate Cancer AJCC v8|Stage IIIB Prostate Cancer AJCC v8|Stage IIIC Prostate Cancer AJCC v8
Interventions: RADIATION: High-Dose Rate Brachytherapy|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Analysis of the Influence of Using the Skin Care Products on the Diaper Area in Comparison With Using a Cotton Wool Cloth, Moistened With Clear Water on the Skin Physiology of the Newborns From the 1st Day to the 4th Week of Life
Status: COMPLETED
Conditions: Postnatal Skin Physiology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Effect of APRF With DFDBA Compare to Collagen Membrane With DFDBA in Intraosseous Defect
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Advanced- platelets rich fibrin (A-PRF) with Demineralized freeze-dried bone allograft (DFDBA)|PROCEDURE: Collagen membrane with Demineralized freeze-dried bone allograft (DFDBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-interventional Study to Observe the Computed Tomographic Angiography Image Quality With Different Contrast Media Injection Protocols Under Different Computed Tomography Machines Parameters Setting
Status: COMPLETED
Conditions: Angiography|Multidetector Computed Tomography
Interventions: DRUG: Iopromide (Ultravist, BAY86-4877)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Improved Onboard Patient Imaging
Status: RECRUITING
Conditions: Head and Neck Cancer|Breast Cancer|Upper Gastrointestinal Cancer|Lung Cancer|Pelvic Cancer
Interventions: DEVICE: HyperSight Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications
Status: COMPLETED
Conditions: Tachycardia
Interventions: DEVICE: Ovatio DR 6550|DEVICE: OVATIO DR 6550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study About Modified RNA Vaccines Against Influenza in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Influenza, Human
Interventions: BIOLOGICAL: Influenza ModRNA Vaccine|BIOLOGICAL: Quadrivalent Influenza Vaccine (QIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery
Status: RECRUITING
Conditions: Infection
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Methazolamide to Lower Intraocular Pressure
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: Methazolamide 25 MG|DRUG: Methazolamide 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ovulation Induction in Clomiphene Citrate Resistant PCO Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: letrozole-metformin|DRUG: letrozole-metformin-pioglitazone|RADIATION: transvaginal ultrasound|OTHER: laboratory investigations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E7389 Versus Capecitabine in Patients With Locally Advanced or Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Eribulin Mesylate|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study With Oral Melphalan + Prednisone (MP) Versus Melphalan, + Prednisone + Thalidomide (MPT) for Newly Diagnosesd Elderly Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan, Prednisone and Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Interaction Study to Assess the Pharmacokinetic Interaction of Oral Administration of Rifapentine on ATRIPLA™ in HIV Patients
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: rifapentine (M000473)|DRUG: EFZ EMT TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Feasibility of Single Session Spine Stereotactic Radiosurgery (SSRS) in the Primary Management in Patients With Inoperable, Previously Unirradiated Metastatic Epidural Spinal Cord Compression (MESCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Epidural Spinal Cord Compression
Interventions: PROCEDURE: Stereotactic Radiosurgery (SSRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose and Multiple Dose Trial to Assess Pharmacokinetics of Obeticholic Acid (OCA)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: OCA 5 mg|DRUG: OCA 10 mg|DRUG: OCA 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Aspirin|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Placebo Administration|DRUG: Zileuton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Fully Human BCMA Chimeric Antigen Receptor Autologous T Cell Injection (CT103A) in the Treatment of Patients With Relapsed/Refractory Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Fully human BCMA chimeric antigen receptor autologous T cell injection (CT103A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non Inferiority Trial of Locally Manufactured Meningococcal ACWY Vaccine 'Ingovax ACWY' in Bangladesh.
Status: COMPLETED
Conditions: Meningococcal Vaccine
Interventions: BIOLOGICAL: Ingovax ACWY|BIOLOGICAL: Quadri Meningo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Asses Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of AZD0328 in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: AZD0328|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Pharmacokinetics and Safety of BCD-055 and Remicade in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Infliximab (BCD-055)|DRUG: Infliximab (Remicade)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Surgery: Comparison of Conventional Trocars to the Teleflex® MiniLap® System
Status: COMPLETED
Conditions: Gynecologic Surgeries
Interventions: DEVICE: laparoscopic gynecologic surgery with the MiniLap System.|DEVICE: laparoscopic gynecologic surgery with the conventional single-use trocars.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness for Parents of OCD-affected Children
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Skills Training (MBST)|OTHER: Waitlist control (WLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Intra-Arterial Administration of Ipilimumab in Combination With Intra-venous Nivolumab for Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules
Status: UNKNOWN
Conditions: Pulmonary Nodule, Solitary|Pulmonary Nodule, Multiple
Interventions: PROCEDURE: Preoperative Infusion of Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety, Tolerability and Pharmacokinetics Study of ZB001 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ZB001 for injection|DRUG: ZB001 for injection|DRUG: ZB001 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Energy Cost for Holding a MedGem® Indirect Calorimeter
Status: COMPLETED
Conditions: Resting Metabolic Rate
Interventions: DEVICE: Not holding, then holding the MedGem®|DEVICE: Holding, then not holding the MedGem®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Controlled Clinical Study of 2 Different Moisturizers for the Relief of Dry Skin
Status: COMPLETED
Conditions: Skin|Skin Care|Skin Cream
Interventions: DRUG: Moisturizer A, F#9155-005|OTHER: Moisturizer B, F#E1387-004|PROCEDURE: Regression|PROCEDURE: Non-Regression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Gait Biofeedback and Impairment-based Rehabilitation in Individuals With Chronic Ankle Instability
Status: UNKNOWN
Conditions: Ankle Sprains|Ankle Injuries
Interventions: OTHER: Gait Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Therapy in Treating Patients With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: monoclonal antibody anti-anb3 integrin|PROCEDURE: anti-cytokine therapy|PROCEDURE: antiangiogenesis therapy|PROCEDURE: antibody therapy|PROCEDURE: biological response modifier therapy|PROCEDURE: growth factor antagonist therapy|PROCEDURE: monoclonal antibody therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Paroxetine|BEHAVIORAL: Prolonged Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: protein expression analysis|OTHER: cytology specimen collection procedure|OTHER: laboratory biomarker analysis|OTHER: physiologic testing|PROCEDURE: breast duct lavage|PROCEDURE: endoscopic biopsy|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger
Status: UNKNOWN
Conditions: Trigger Finger
Interventions: DRUG: hyaluronic acid (20 mg/2 mL)|DRUG: Triamcinolone acetonide 10mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Intervention Framework for Children With Autism Spectrum Disorder to Enhance Social Engagement and Participation
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Social Engagement|Robotic Intervention
Interventions: BEHAVIORAL: Robot-assisted social skill intervention|BEHAVIORAL: Human-only instruction programme on social skill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of N-Acetylcysteine on Volumetric Retention of Autologous Fat Graft for Breast Asymmetry Correction
Status: UNKNOWN
Conditions: Breast; Deformity, Congenital|Graft Loss|Adipose Tissue Atrophy|Breast; Atrophy
Interventions: DRUG: N-Acetylcysteine (NAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Intravenous and Perineural Dexmedetomidine in Gastric Cancer Surgery
Status: UNKNOWN
Conditions: Gastric Cancer|Pain, Postoperative
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% Sodium-chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients
Status: RECRUITING
Conditions: Actinic Keratosis
Interventions: PROCEDURE: Biopsy|DRUG: Calcipotriene|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: DT1 Toric contact lenses|DEVICE: AO1DfA contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Relative Bioavailability of Telmisartan/Amlodipine Fixed-dose Combination Compared to Its Mono-components in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan/amlodipine fixed-dose combination (FDC) tablet|DRUG: Telmisartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test of a New Gel-based Colon Cleansing Agent Compared to Moviprep
Status: UNKNOWN
Conditions: Pharmacological Action
Interventions: DRUG: A 06 ad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
Status: COMPLETED
Conditions: Dental Fluorosis|Dental Caries
Interventions: OTHER: Low fluoride and conventional dentifrices with different pH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
Status: COMPLETED
Conditions: Obesity|Diabetes|Hypertension|Hyperlipidemia
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Reduced Calorie Diet|BEHAVIORAL: Weight Maintenance Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment
Status: NOT_YET_RECRUITING
Conditions: Opioid-Related Disorders|Psychosocial Functioning|Quality of Life
Interventions: BEHAVIORAL: ACT to RECOVER|BEHAVIORAL: Smartphone-based Symptom-Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of a Physical Training Structured Program After a Pulmonary Thromboembolism
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: BEHAVIORAL: Pulmonary Rehabilitation program|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infections
Interventions: BIOLOGICAL: ABU bladder lavage|BIOLOGICAL: Saline bladder lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation - A Phase IIA Proof of Concept Study of Regorafenib (Bayer 73-4506) in Biopsy-amenable Asian Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Asian Colorectal Cancer Patients
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cevostamab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Mouth Rinses With Commercial Mouthwashes to Decrease Viral Load in Saliva in COVID-19 Patients
Status: COMPLETED
Conditions: covid19
Interventions: DRUG: Lacer Clorhexidina Colutorio|DRUG: Lacer Clorhexidine 0.20% Colutorio|DRUG: Gingilacer Encías Delicadas Colutorio|DRUG: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC
Status: RECRUITING
Conditions: Tracheobronchomalacia|Excessive Dynamic Airway Collapse
Interventions: DEVICE: Continuous positive airway pressure (CPAP) device|DEVICE: Sham-continuous positive airway pressure (CPAP) device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Versus Mirror Therapy on Balance and Muscle Strength in Children With Hemiplegic Cerebral Palsy
Status: UNKNOWN
Conditions: Rehabilitation
Interventions: OTHER: designed physical therapy program in addition to program of virtual reality.|OTHER: designed physical therapy program in addition to program of mirror therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Cognitive Training Approaches in Psychotic Disorders
Status: COMPLETED
Conditions: Psychotic Disorders
Interventions: BEHAVIORAL: Cognitive Remediation - Executive Training|BEHAVIORAL: Cognitive Remediation - Perceptual Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT