pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of the Safety and Leukostimulatory Activity of the Preparation "Panagen" in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Panagen|DRUG: Placebo|PROCEDURE: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aliskiren and Renin Inhibition in Diastolic Heart Failure
Status: WITHDRAWN
Conditions: Diastolic Heart Failure
Interventions: DRUG: Aliskiren plus spironolactone vs. Lisinopril plus spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: 8-Chloroadenosine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LifeSprout Lumina™ Study in the Treatment of Nasolabial Folds
Status: UNKNOWN
Conditions: Nasolabial Fold
Interventions: DEVICE: Study Product|DEVICE: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase III Study of Nazartinib (EGF816) Versus Erlotinib/Gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating Mutations
Status: WITHDRAWN
Conditions: Carcinoma, Non-small Cell Lung
Interventions: DRUG: EFG816|DRUG: erlotinib or gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Neurocognitive Functions by Hippocampal Sparing Radiotherapy
Status: UNKNOWN
Conditions: Radiation of Neurocranial Region
Interventions: RADIATION: Radiation according to indication with hippocampal sparing|RADIATION: Radiation according to indication without hippocampal protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MLN8237 to Treat Children With Relapsed/Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Excluding CNS|Neuroblastoma
Interventions: DRUG: MLN8237
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Secondhand Exposure to E-cigarettes Aerosols on the Respiratory System
Status: UNKNOWN
Conditions: Second Hand Tobacco Smoke
Interventions: OTHER: Secondhand exposure to e-cigarette aerosols (low)|OTHER: Secondhand exposure to e-cigarette aerosols (high)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lumbar Paravertebral in Hernia Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Lumbar paravertebral group|DRUG: The field block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obesity and Intracytoplasmic Sperm Injection Cycle Outcome
Status: COMPLETED
Conditions: Infertility
Interventions: DIAGNOSTIC_TEST: Visceral fat thickness|DIAGNOSTIC_TEST: Body mass index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gemcitabine Combined With Apatinib and Toripalimab in Recurrent or Metastatic Nasopharyngeal Carcinoma.
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine combined with Aptinib and Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Fosaprepitant and Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting in Pediatric Caner Patients
Status: UNKNOWN
Conditions: Chemotherapy Induced Nausea and Vomiting|Pediatric Cancer Patients
Interventions: DRUG: fosaprepitant|DRUG: aprepitant|DRUG: Granisetron plus dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Role of Gum Chewing in Regaining Bowel Motility in Patients Undergoing Cesarean Section
Status: COMPLETED
Conditions: Effect of Gum Chewing on Regaining Bowel Motility After Cesarean Section
Interventions: DRUG: sugarless gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: TENS for Testicular Pain (ICO): A Randomized Controlled Trial
Status: COMPLETED
Conditions: Pain Management
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Investigation to Evaluate the Safety and Performance of 877PTY Toric IOL for Visual Correction of Corneal Astigmatism
Status: ENROLLING_BY_INVITATION
Conditions: Cataract|Corneal Astigmatism
Interventions: DEVICE: 877PTY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimizing the Scalability of Evidence-Based Behavioral Sleep Medicine Practices With a Digital Health Platform
Status: ACTIVE_NOT_RECRUITING
Conditions: Implementation; Digital Health|Chronic Insomnia
Interventions: OTHER: No Facilitation Support|OTHER: External Facilitation Support|OTHER: External and Internal Facilitation Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Personalized and Remote Support Centered on Exercise and Physical Activity for Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Female
Interventions: OTHER: Personalized Coaching (Arm A)|OTHER: Standard supportive approach (Arm B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of an Artificial Intelligent Tutoring System in Simulation Training
Status: COMPLETED
Conditions: Surgical Education
Interventions: BEHAVIORAL: Virtual Operative Assistant Training|BEHAVIORAL: Remote-Based Expert Instructor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. Pylori
Status: UNKNOWN
Conditions: Helicobacter Infections|Gastritis|Gastric Ulcer|Duodenal Ulcer
Interventions: DRUG: Lansoprazole, clarithromycin, amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetics (PK) and Safety Study of Oral Fampridine-PR 10 mg in Chinese, Japanese, and Caucasian Adult Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIB041 (Fampridine-PR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph2 Gem/Nov/Rituxan Rel/Ref MantleCell
Status: COMPLETED
Conditions: Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Interventions: DRUG: gemcitabine|DRUG: mitoxantrone|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Hypoxic-Ischemic Encephalopathy|Caffeine
Interventions: DRUG: Caffeine citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Two Recall Intervals on Dental Caries Incidence and Other Outcomes of Preschool Children
Status: UNKNOWN
Conditions: Dental Caries|Quality of Life|Anxiety
Interventions: PROCEDURE: Oral Clinical conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Contrast Enhanced Ultrasound and Shear Wave Elastography in Measuring Response in Patients With Breast Cancer Receiving Chemotherapy Before Surgery
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: dynamic contrast-enhanced ultrasound imaging|PROCEDURE: shear wave elastography|DRUG: Definity, (Lipid Microspheres) Intravenous Suspension|DEVICE: Philips Shear Wave Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel mGluR5 Modulator Effects on Alcohol Drinking and MRI Outcomes
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Placebo|DRUG: GET73
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal Cancer Stage III
Interventions: DRUG: Oxaliplatin, 85 mg/m2|DRUG: 5FU; 2400 mg/m2|DRUG: 5FU, 250 mg/m2|DRUG: 5FU, 2400 mg/m2|DRUG: Oxaliplatin 50 mg/m2|DRUG: Folinic Acid, 400 mg/m2|RADIATION: Radiotherapy control, 5x5 Gy: 25 Gy|DRUG: Capecitabine, 1000 mg/m2|DRUG: Oxaliplatin 85 mg/m2|RADIATION: radiotherapy experimental, 30 x 1,8 Gy: 54 Gy|DRUG: Capecitabine, 825 mg/m2|DRUG: Oxaliplatin, 130 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IMAGINATOR 2.0: Co-design and Early Evaluation of a Novel Blended Digital Intervention Targeting Self-harm in Young People
Status: COMPLETED
Conditions: Self Injurious Behavior|Adolescent Behavior Problem|Child Behavior Problem|Mental Health Disorder
Interventions: OTHER: Imaginator 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breathing Device for Orthostatic Hypotension (OH)
Status: WITHDRAWN
Conditions: Orthostatic Hypotension
Interventions: DEVICE: Inspiratory Threshold Device (Res-Q-Gard ITD)|DEVICE: Sham Inspiratory Threshold Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of EILO Among Children With Asthma
Status: NOT_YET_RECRUITING
Conditions: Exercise Induced Laryngeal Obstruction|Asthma in Children|Exercise-Induced Bronchospasm|Exercise-Induced Bronchoconstriction|Dyspnea|Larynx
Interventions: DIAGNOSTIC_TEST: Continuous Laryngoscopy during Exercise Test (CLE test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Group-Based Lifestyle Intervention in Measuring Biomarker Levels in Participants at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Atypical Ductal Breast Hyperplasia|Atypical Lobular Breast Hyperplasia|BRCA1 Mutation Carrier|BRCA2 Mutation Carrier|Ductal Breast Carcinoma in Situ|Lobular Breast Carcinoma in Situ
Interventions: OTHER: counseling intervention|BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|OTHER: questionnaire administration|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction
Status: TERMINATED
Conditions: Congestive Heart Failure|Renal Insufficiency
Interventions: DRUG: Hypertonic saline, then oral sodium chloride|DRUG: Normal saline, then oral placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRAUMA HELP: Healing and Analgesia With Propranolol
Status: WITHDRAWN
Conditions: Trauma
Interventions: DRUG: Propranolol|DRUG: Propranolol ER|DRUG: Sugar pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib Plus Tegafur Gimeracil Oteracil in Recurrent/Metastatic Head and Neck Cancers
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Apatinib Mesylate Tablets|DRUG: Tegafur Gimeracil Oteracil Potassium Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buscopan in Patients Undergoing IVF/Intracytoplasmic Sperm Injection Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: IVF|Intracytoplasmic Sperm Injection
Interventions: DRUG: Buscopan 20 milligrams/ML Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: LITT Followed by Hypofractionated RT for Recurrent Gliomas
Status: RECRUITING
Conditions: Glioblastoma|Brain Tumor|Glioma|Neoplasms
Interventions: DEVICE: Procedure: LITT|RADIATION: Hypo-Fractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial Craniotomy
Status: COMPLETED
Conditions: Brain Tumor|Intracranial Pressure
Interventions: DRUG: Mannitol|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Efficacy of Ibuprofen 800 mg in a Walking Model of Osteoarthritis Pain (0000-057)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Blood Pressure Control Ability Between HPI, ClearSight, and Conventional NIBP During Neuraxial Anesthesia in Cesarean Section
Status: RECRUITING
Conditions: Intraoperative Hypotension|Cesarean Section
Interventions: DEVICE: hypotension prediction index derived from non-invasive arterial pressure waveforms|DEVICE: non-invasive arterial pressure waveforms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Different Volumes of Erector Spinae Plane Block for Breast Surgery
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms|Breast Diseases
Interventions: DRUG: Bupivacaine + Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Arthrogenic Muscular Inhibition in Patellofemoral Pain and the Response to an Exercise Programme
Status: UNKNOWN
Conditions: PFP|Patellofemoral Pain|Anterior Knee Pain
Interventions: OTHER: 6 week exercise treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of a Novel Glucose Sensing Technology in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: Sensor Based Glucose Monitoring System|DEVICE: Standard Blood Glucose Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SCHF Post-Op Study Between Opioid and Non-Opioid Pain Management
Status: ENROLLING_BY_INVITATION
Conditions: Supracondylar Humerus Fracture
Interventions: DRUG: Hydrocodone/acetaminophen|DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: ORCA-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose, Randomized, Two-period, Two-treatment, Two-sequence, Crossover Bioequivalence Study on a Olostar Tab Versus Two Co-administered Reference Products Olmesartan Medoxomil and Rosuvastatin Calcium in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Olostar Tab.|DRUG: Co-administration of Olmetec and Crestor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Behavioral Pharmacology of THC and Beta-Myrcene
Status: NOT_YET_RECRUITING
Conditions: Cannabis Use
Interventions: DRUG: Placebo|DRUG: THC|DRUG: Beta-Myrcene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vibration Therapy as a Rehabilitation Intervention for Postural Training and Fall Prevention
Status: COMPLETED
Conditions: Distal Radius Fracture|Fall Patients
Interventions: DEVICE: Low-magnitude high-frequency vibration (LMHFV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701)
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Leukemia, Myeloid, Chronic|Blast Crisis|Leukemia, Lymphocytic
Interventions: DRUG: Farnesyl Protein Transferase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Urethral Stricture
Interventions: DEVICE: Urotronic Drug Coated Balloon (DCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Bowen's Technique and Myofascial Release Technique On Pain And Disability in Trapezitis
Status: COMPLETED
Conditions: Trapezius Muscle Strain
Interventions: OTHER: experimental Bowen Technique|OTHER: Experimental Myofacial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of CNTO 1275 Compared to Etanercept in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: CNTO 1275 45 mg|DRUG: CNTO 1275 90 mg|DRUG: Etanercept 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Children to Evaluate the Immunogenicity and Safety of 4 Formulations of GSK Bio MenACWY-TT Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Conjugated meningococcal ACWY-TT (vaccine)|BIOLOGICAL: DTPa/Hib containing vaccine|BIOLOGICAL: Meningitec|BIOLOGICAL: Mencevax ACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Saphenous Vein Reflux With 1920-nm Diode Laser
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DEVICE: Endovenous 1920-nm diode laser|DEVICE: Endovenous 1470-nm diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Buprenorphine|DRUG: Tramadol|DEVICE: Oral Mucositis (OM) Pain App
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Sensitization of Non-M3 AML Blasts to ATRA by Epigenetic Treatment With Tranylcypromine (TCP)
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: tranylcypromine|DRUG: all-trans retinoic acid|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
Status: RECRUITING
Conditions: Clinical Stage I Gastric Cancer AJCC v8|Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage II Gastric Cancer AJCC v8|Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Gastric Cancer AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biospecimen Collection|DRUG: Capecitabine|PROCEDURE: Computed Tomography|DRUG: Docetaxel|PROCEDURE: Echocardiography|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|PROCEDURE: Lymphadenectomy|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|PROCEDURE: Positron Emission Tomography|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Diagnostic Study on Perforator Localization of Anterolateral Thigh Flap With Perforator Locator
Status: RECRUITING
Conditions: Blood Vessel Perforation
Interventions: DEVICE: perforator locator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pH
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Aggrenox|DRUG: Dipyridamole|DRUG: Aspirin|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Ultrasound in Patients With Carpal Tunnel Syndrome
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: low intensity pulsed ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentrique Prospective Evaluation of Radiofrequency Surgical Treatment of Homorrhoidal Disease
Status: UNKNOWN
Conditions: Hemorrhoids|Surgical Procedure, Unspecified
Interventions: PROCEDURE: Radiofrewuency surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE VIABAHN ENDOPROSTHESIS Peripheral Vascular Disease Study
Status: COMPLETED
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: GORE VIABAHN Endoprosthesis|DEVICE: Bare Nitinol Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Clinical Efficacy and Safety of Recombinant Human Interferon ω Spray in Treatment of Viral Upper Respiratory Tract Infection in Children
Status: NOT_YET_RECRUITING
Conditions: Viral Upper Respiratory Tract Infection
Interventions: DRUG: recombinant human interferon ω spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delayed Cord Clamping in Infants Born by Cesarean Section
Status: COMPLETED
Conditions: Umbilical Cord Management|Elective Cesarean Section
Interventions: PROCEDURE: Delayed cord clamping|PROCEDURE: Early cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DRUG: BNO 1016
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Intensity Body-weight Circuit Training Feasibility and Efficacy for in Middle Aged Persons With Type 2 Diabetes
Status: RECRUITING
Conditions: Type2diabetes
Interventions: BEHAVIORAL: high intensity body-weight circuit|BEHAVIORAL: traditional exercise intervention (TEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Absorption and Excretion Kinetics of the Bioactive Ingredients of Rice Bran Extract
Status: COMPLETED
Conditions: Safety After Oral Intake|Pharmacokinetics After Oral Intake
Interventions: DIETARY_SUPPLEMENT: Rice bran extract|DIETARY_SUPPLEMENT: Porridge in water|DIETARY_SUPPLEMENT: Porridge in milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Combined Use of Anti-fibrotic Agent With Platelet Rich Plasma on Skeletal Muscle Healing After Acute Injuries
Status: COMPLETED
Conditions: PRP|Losartan|Muscle Injury|Sport Injury
Interventions: BIOLOGICAL: Autologous platelets rich plasma|COMBINATION_PRODUCT: Autologous platelets rich plasma + oral LOSARTAN administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease|Angina, Unstable|Angina, Stable|STEMI - ST Elevation Myocardial Infarction|NSTEMI - Non-ST Segment Elevation MI|Contrast-induced Nephropathy|Acute Kidney Injury
Interventions: OTHER: Iodinated contrast
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Clinical Trial of NPB-01 in Patients With Anti-aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder Not Provided Adequate Effect of Therapy to Steroids Plus Therapy.
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: NPB-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myopia Control: a Comparison Study Between Atropine and MiSight
Status: NOT_YET_RECRUITING
Conditions: Myopia
Interventions: DRUG: Atropine|DEVICE: MiSight contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Cephalexin Tablets 1g
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: Cephalexin 1g tablets|DRUG: Cephalexin 1g tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.
Status: TERMINATED
Conditions: Obesity, Childhood|Neural Development
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Different Lung Ultrasound Imaging Protocols in COVID-19 Pneumonia
Status: COMPLETED
Conditions: Lung Ultrasound|Pneumonia|Covid19
Interventions: DEVICE: LUS Twelve area|DEVICE: LUS Fourteen area
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: CAPEOX adjuvant therapy|OTHER: deferred CAPEOX adjuvant therapy|OTHER: mFOLFOXIRI intensive adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Hybrid Cardiac Rehabilitation Trial on Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III
Interventions: OTHER: Comprehensive Initial Assessment|OTHER: Continuous evaluation|OTHER: Interval Exercise|BEHAVIORAL: Psychosocial support|OTHER: Diet management|OTHER: Resistance exercise|OTHER: Continuous exercise|OTHER: Initial Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2
Status: RECRUITING
Conditions: Suicide|Psychosis
Interventions: BEHAVIORAL: Cognitive Behavioral Suicide Prevention for psychosis (CBSPp)|BEHAVIORAL: Services as Usual (SAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12 Week Physical Training Programme for Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Training in water|BEHAVIORAL: Training on land
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Dose Mivacurium vs. Low Dose Succinylcholine for Rigid Bronchoscopy
Status: COMPLETED
Conditions: Intubating Conditions|Performance With Respiratory Exercise Device|Postoperative Myalgia
Interventions: DRUG: Succinylcholine|DRUG: Mivacurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Listening to Music During CPAP on the Agitation Levels and Compliance.
Status: COMPLETED
Conditions: COVID-19|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DEVICE: Listening to music with a bluetooth headset to patients receiving CPAP support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Kinesio Taping in Patellofemoral Pain
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome
Interventions: DEVICE: Kinesio Taping|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: USG Imaging of Brachial Plexus Sheath & Its Fascial Compartments at Costoclavicular Space & Infraclavicular Fossa
Status: COMPLETED
Conditions: Musculoskeletal Diseases or Conditions
Interventions: PROCEDURE: Ultrasound guided Costoclavicular Brachial Plexus Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of tDCS Versus HD-tDCS for Stroke Rehabilitation
Status: COMPLETED
Conditions: Chronic Aphasia
Interventions: DEVICE: HD-tDCS (Soterix)|DEVICE: Transcranial Direct Current Stimulation (Neuroconn)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adapted Physical Activity on a Walking Platform in Elderly Patients HOspitalized for Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Oncology|Elderly Patients|Surgery
Interventions: DEVICE: Early rehabilitation through Adapted Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Synergy, Self-efficacy, Breastfeeding and Care (SInergia, Autoeficacia, Lactancia y Cuidados)
Status: COMPLETED
Conditions: Breast Feeding|Self Efficacy
Interventions: BEHAVIORAL: Breastfeeding support
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Acceptance and Commitment Therapy on Fatigue Interference in Patients With Advanced Lung Cancer and Caregiver Burden (ACT)
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Advanced Cancer|Caregiver Burden
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT) plus health education|OTHER: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Transdermal Fentanyl Patch to Treat Postoperative Pain in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: transdermal fentanyl patch|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Total Versus Partial Omentectomy in the Treatment of Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms|Interleukin|Stomach Cancer|Gastric Cancer|Digestive System Neoplasm
Interventions: PROCEDURE: Partial omentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient and Provider Glucose Reporting Preferences Ambulatory Glucose Profile (AGP)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Continuous Glucose Monitor|DEVICE: Self Monitoring Blood Glucose|OTHER: Clinician
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The STEREO-DBS Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation
Status: RECRUITING
Conditions: Parkinson Disease|Diffusion Magnetic Resonance Imaging|Brain|Subthalamic Nucleus|Deep Brain Stimulation|Human|Treatment Outcome
Interventions: PROCEDURE: 7T MRI network analysis for deep brain stimulation in Parkinson's disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Efficacy of Duloxetine and Pregabalin in Patients With Knee Osteoarthritis With Mix Type Pain
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Duloxetine|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
Status: RECRUITING
Conditions: Bronchiolitis
Interventions: DEVICE: Standard Non-Invasive Mechanical Servo Ventilation|DEVICE: Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Pharmacokinetic Drug Interaction Between Tadalafil and Tamsulosin
Status: COMPLETED
Conditions: Erectile Dysfunction|Benign Prostatic Hyperplasia
Interventions: DRUG: Tadalafil|DRUG: Tamsulosin|DRUG: Tadalafil + Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis
Status: COMPLETED
Conditions: Vulvar Diseases|Vulvar Pain|Vestibulitis|Vestibulodynia|Vulvodynia
Interventions: DRUG: Nifedipine cream topical application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of Osteopathic Principles for Nonpharmacologic, Therapeutic Interventions in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: OMT|OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Compassion Training to Patients Undergoing HSCT on Biological and Psychosocial Parameters
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplant
Interventions: BEHAVIORAL: CBCT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Activation of Brown Adipose Tissue Thermogenesis in Humans Using Formoterol Fumarate (GB10)
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DRUG: Formoterol Fumarate 12 micrograms Inhalation Powder|DRUG: Nicotinic Acid 50 MG Oral Tablet|OTHER: Acute Cold Exposure|DIAGNOSTIC_TEST: Positron Emission Tomography (PET)|DIAGNOSTIC_TEST: Indirect calorimetry|DIAGNOSTIC_TEST: dual-energy x-ray absorptiometry (DEXA scan)|PROCEDURE: Biopsy|PROCEDURE: iv lines|PROCEDURE: Electromyogram (EMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial Study of the Efficacy of Intensive Preoperative Pelvic Floor Muscle Training to Decrease Post-prostatectomy Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training 3 weeks before radical prostatectomy|BEHAVIORAL: Intensive preoperative pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Maternal Role Training Program on Maternal Role Attainment Mother Infant and Father Infant Attachment
Status: COMPLETED
Conditions: Care Pattern, Maternal
Interventions: BEHAVIORAL: (Maternity Identity Development Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telemedicine Home-based Management in Patients With CHF and Type 2 Diabetes
Status: RECRUITING
Conditions: Chronic Heart Failure|Diabetes Mellitus
Interventions: OTHER: Teleassistance|OTHER: Teleconsultation|OTHER: Telerehabilitation|OTHER: Telemonitoring|OTHER: mHealth|OTHER: telepsycology|OTHER: Quality of life|OTHER: Biochemistry evaluation|OTHER: Clinical evaluation|OTHER: State of health of the patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting Women in the UK Armed Forces Who Consume Alcohol at an Increased Risk: Refining the DrinksRation Platform
Status: RECRUITING
Conditions: Alcohol Abuse|Alcohol Drinking|Alcohol Use Disorder
Interventions: BEHAVIORAL: DrinksRation|BEHAVIORAL: BeAlcoholSmart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anxiety on Cardiac Substrate Modification in Women With Atrial Fibrillation Undergoing Catheter Ablation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|AML Stage, Adult
Interventions: DRUG: Venetoclax Combining Chidamide and Azacitidine (VCA) regimen followed by dicitabine combined with liposome mitoxantrone, cytarabine, and G-CSF (D-MAG) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thiopurine Enhanced Mutations for PD-1/Ligand-1 Efficacy
Status: RECRUITING
Conditions: Solid Tumor, Adult|Metastatic Cancer
Interventions: COMBINATION_PRODUCT: Atezolizumab, 6-mercaptopurine, 6-thioguanine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
Status: RECRUITING
Conditions: Locally Advanced Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Ductal Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Nab-paclitaxel|DRUG: Fluorouracil|DRUG: Irinotecan Hydrochloride|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|OTHER: Perflubutane Microbubble|PROCEDURE: Contrast-Enhanced Ultrasound|OTHER: Quality-of-Life Assessment|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: McConnell Patellar Taping in Static and Dynamic Postural Control of Women With Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: taping patellar McConnell|OTHER: Placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Safety and Efficacy of Combigan® and Lumigan® With Lumigan® Alone in Glaucoma or Ocular Hypertension Subjects Treated With Xalatan®
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: fixed combination of brimonidine tartrate 0.2% timolol maleate 0.5% ophthalmic solution; bimatoprost 0.03% ophthalmic solution|DRUG: bimatoprost 0.03% ophthalmic solution; hypromellose 0.2% eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reading Together: How to Promote Children's Language Development Using Family-based Shared Book Reading
Status: COMPLETED
Conditions: Language Development
Interventions: BEHAVIORAL: Reading Together - Pausing for Reading|BEHAVIORAL: Reading Together - Dialogic Reading|BEHAVIORAL: Reading Together - Shared Reading Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Tacrolimus (Prograf Capsule/Injection) and Methotrexate (MTX) Combination Therapy for Prevention of Graft Versus Host Disease (GVHD) in Patients Who Received Peripheral Hematopoietic Stem Cell Transplantation From a Sibling Donor
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Prograf|DRUG: Methotrexate|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of KL-7SHRNA Injection Solution in the Treatment of AIDS Patients With Lymphoma
Status: RECRUITING
Conditions: HIV Infections|Lymphoma
Interventions: DRUG: KL-7SHRNA injection solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Progressive Relaxation Exercise and Sleep Hygiene Training on Sleep Quality and AnxietyLevel Given to Outpatients With Anxiety Disorder in Psychiatry Clinic
Status: RECRUITING
Conditions: Anxiety Disorder/Anxiety State
Interventions: BEHAVIORAL: Progressive relaxation exercises and sleep hygiene training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Dextroamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors|Microsatellite Instability Low|Microsatellite Instability High|Microsatellite Stable|Ovarian Cancer|Gastric Cancer|Colo-rectal Cancer|Esophageal Cancer|Endometrial Cancer|Head Neck Cancer|Cervical Cancer|Lung Cancer
Interventions: DRUG: NC410|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT