pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Risk Adapted Therapy Optimization for Patients With Relapsed or Refractory Aggressive Non-Hodgkin-Lymphoma
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Rituximab|DRUG: DHAP|DRUG: TEC|DRUG: autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TMC435-TiDP16-C107: This Study Measures the (Possible) Influence of TMC435 on the Activity of a Selected Set of Drug-degrading Proteins by Measuring the Blood Levels of Drugs That Have Been Taken Together With TMC435 and That Are Known to be Specifically Degraded by These Drug-degrading Proteins.
Status: COMPLETED
Conditions: Hepatitis C|Viruses
Interventions: DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreaticoduodenectomy With or Without Braun Enteroenterostomy: Comparison of Postoperative Pancreatic Fistula and Delayed Gastric Emptying
Status: TERMINATED
Conditions: Postoperative Pancreatic Fistula|Delayed Gastric Emptying
Interventions: PROCEDURE: pancreaticoduodenectomy without Braun enteroenterostomy|PROCEDURE: Braun enteroenterostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mixed Chimera Allogeneic Transplantation From Matched Unrelated Donors For The Treatment Of Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Autologous followed by non-myeloablative allogeneic transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding and Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis|Crohn's Disease|Depression
Interventions: BEHAVIORAL: Primary and Secondary Coping Enhancement Training|BEHAVIORAL: Supportive Non-directive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MASC: Reducing Stress for Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease and Related Dementias|Dementia Alzheimers
Interventions: BEHAVIORAL: MASC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome|Neonatal Opioid Withdrawal|Neonatal Opioid Withdrawal Syndrome
Interventions: DRUG: Morphine PRN|DRUG: Morphine scheduled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Clinical Evaluation of Beta-D-Glucan Assay in Blood and BAL
Status: COMPLETED
Conditions: Invasive Fungal Infection|Hematological Malignancy|Receipt of Solid Organ Transplant
Interventions: OTHER: Fungitell Assay in BAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Triple-negative Breast Cancer With Albumin-bound Paclitaxel as Neoadjuvant Therapy: a Prospective RCT
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: nab-Paclitaxel+carboplatin|DRUG: Paclitaxel+carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.
Status: COMPLETED
Conditions: Ewing Sarcoma of Bone|Osteosarcoma
Interventions: DRUG: Tranexamic acid injection|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pembrolizumab in Combination With Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Colorectal Cancer
Interventions: DRUG: Pabolizumab+ bevacizumab and CapeOX (bevacizumab + oxaliplatin + capecitabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Pharmacokinetics and Safety of Single Doses of JNJ-54452840 in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54452840|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis
Status: RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: PIPE-307 Dose A|DRUG: PIPE-307 Dose B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid Sodium Salt and Hydeal-D in the Management of LUTS After TURBT for NMIBC.
Status: TERMINATED
Conditions: Non-muscle Invasive Bladder Cancer (NMIBC)
Interventions: DEVICE: Hyaluronic Acid (HA) sodium salt and Hydeal-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Awal (Early) Testing & Treatment Indonesia Project Intervention Phase
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DIAGNOSTIC_TEST: Oral Fluid Based Self Testing|PROCEDURE: Simplified ART Initiation|PROCEDURE: CBO AND BROTHEL-BASED ART SERVICE|BEHAVIORAL: SMS REMINDER|PROCEDURE: MOTIVATIONAL INTERVIEWING
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Enhancement of Treatment of Delusions in Schizophrenia Through Neuromodulation
Status: WITHDRAWN
Conditions: Schizophrenia|Psychosis|Delusions
Interventions: BEHAVIORAL: Metacognitive Training (MCT)|BEHAVIORAL: Sham/MCT|DEVICE: transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Short-contact Plaque Test Study With Daivobet® Gel in Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Daivobet® gel applied then removed after 10 minutes (+/- 2 minutes)|DRUG: Daivobet® gel applied then removed after 20 minutes (+/- 2 minutes)|DRUG: Daivobet® gel applied for 24 hours (+/- 2 hours)|DRUG: Daivobet® gel vehicle applied for 24 hours (+/- 2 hours)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Test a Measure of Symptoms of Older Men With Low Testosterone On and Off Testosterone Replacement Treatment (P05815)
Status: TERMINATED
Conditions: Hypogonadism
Interventions: DRUG: Testim 1% (testosterone gel)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vertical Versus Horizontal Plicataion in Transperienal Repair of Rectocele
Status: COMPLETED
Conditions: Rectocele
Interventions: PROCEDURE: Vertical plication|PROCEDURE: Horizontal plication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Hemodialysis Affect Upper Extremity Functional Capacity, Physical Activity and Physical Function of Patients?
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DIAGNOSTIC_TEST: Hand grip, joint range of motion , functional level of the upper extremity, physical activity levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Impact of Acute Normovolemic Hemodilution on Blood Viscosity
Status: COMPLETED
Conditions: Ischemic Heart Disease|Coronary Artery Disease
Interventions: PROCEDURE: acute normovolemic hemodilution|PROCEDURE: In-vitro hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TACE+RFA Versus TACE Alone for Intermediate-stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Chemoembolization, Therapeutic|Ablation Techniques, RFA
Interventions: PROCEDURE: TACE|PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Pimavanserin in Patients With Alzheimer's Disease Psychosis
Status: COMPLETED
Conditions: Alzheimer's Disease Psychosis
Interventions: DRUG: Pimavanserin tartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing the Efficacy and Safety of a New Pain Patch and Placebo in Delayed Onset Muscle Soreness (DOMS)
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: DRUG: Loxoprofen Pain Patch|DRUG: Placebo Patch|DRUG: No Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of IV 10, 20, and 30mg for Renal Colic Pain in the ED
Status: COMPLETED
Conditions: Pain|Renal Colic
Interventions: DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis
Status: COMPLETED
Conditions: Uveitis, Intermediate|Macular Edema|Multiple Sclerosis
Interventions: DRUG: Interferon beta|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity and Safety of Ultrasound-guided Percutaneously Laser Ablation for Refractory Neoplasms
Status: UNKNOWN
Conditions: Refractory Neoplasms
Interventions: PROCEDURE: US-guided laser ablation for refractory neoplasms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Success of Transitioning Uncontrolled Glaucoma Patients From Prior Mono or Adjunctive Therapy to DuoTrav
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Travoprost 0.004%/timolol maleate 0.5% fixed combination ophthalmic solution (DuoTrav)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Engagement in Assisted Therapy Through Exercise Robotics
Status: COMPLETED
Conditions: Stroke|Cerebral Palsy|Traumatic Brain Injury
Interventions: DEVICE: FEATHERS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial
Status: COMPLETED
Conditions: Diabetic Nephropathy|Type 2 Diabetes Mellitus|Proteinuria
Interventions: DRUG: olmesartan medoxomil|DRUG: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
Status: RECRUITING
Conditions: Leukemia|Inborn Errors of Metabolism|Bone Marrow Failure Syndromes|Immunodeficiencies|Immunodysregulation Polyendocrinopathy Enteropathy X-linked Syndrome
Interventions: DEVICE: Transplant of stem cells with CD3+/CD19+ depletion (CliniMACs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Efficacy Study of Second-line Surgery After Percutaneous Needle Aponeurotomy for Dupuytren's Disease.
Status: UNKNOWN
Conditions: Dupuytren's Disease|Surgical Incision
Interventions: PROCEDURE: Surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Allergy|Eczema|Respiratory Tract Infections
Interventions: BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MRI-Volumetry in the Evaluation of Shunt Treatment for Hydrocephalus
Status: COMPLETED
Conditions: Hydrocephalus, Normal Pressure
Interventions: OTHER: Ventriculoperitoneal shunt opening pressure setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Autologous Adipose Tissue Harvested With SEFFICARE Method for Treatment of DFU Minor Amputation
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot|Diabetic Foot Ulcer|Amputation
Interventions: DEVICE: SEFFICARE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VERION Versus Conventional, Manual Ink-marking in Toric IOL Implantation
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: VERION for toric IOL alignment|PROCEDURE: Conventional, manual ink-marking for toric IOL alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Saxagliptin Triple Oral Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Oral Abexinostat in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: DRUG: abexinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol for an Analytical Study With Microbiological, Phenotypic, Genotypic and Multiomics Techniques
Status: UNKNOWN
Conditions: Back Pain, Low|Degenerative Disc Disease
Interventions: PROCEDURE: Lumbar Spinal Fusion Surgery|BIOLOGICAL: Bacterial culture|GENETIC: Phenotypic and genotypic characterization|GENETIC: Multiomics analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors
Status: TERMINATED
Conditions: Advanced Synovial Sarcoma
Interventions: DRUG: FHD-609
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-port, Two-port Versus Three-port VATS on Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Neoplasm
Interventions: PROCEDURE: Three-port pulmonary resection surgery|PROCEDURE: Single-port or two-port surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Patients With Neovascular AMD Using Indocyanine Green-Mediated Photothrombosis (i-MP).
Status: UNKNOWN
Conditions: Maculopathy, Age-Related
Interventions: PROCEDURE: Indocyanine Green-Mediated Photothrombosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Risk of Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease|Autonomic Nervous System Diseases|Pure Autonomic Failure
Interventions: DRUG: 6-[18F]Fluorodopamine|DRUG: 6-[18F]Fluorodopa|DRUG: 13N-Ammonia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Catheter-over-needle: Inpatient Study
Status: TERMINATED
Conditions: Local Anesthesia|Catheterization
Interventions: PROCEDURE: Catheter-over-needle|PROCEDURE: Catheter-through-needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India
Status: RECRUITING
Conditions: Transthyretin Amyloid Cardiomyopathy
Interventions: DRUG: Tafamidis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Of Radiation Exposure To Patients During Endoscopic Retrograde Cholangiopancreatography (ERCP) Performed By Endoscopists Trained In Judicious Use Of Fluoroscopy With Those Without Formal Training
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: OTHER: Endoscopic retrograde cholangiopancreatography - No Intervention have been used other than standard of care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Plate Stabilization to Conservative Treatment in Midshaft Clavicle Fractures
Status: COMPLETED
Conditions: Clavicle|Fracture
Interventions: PROCEDURE: Operative treatment|PROCEDURE: Non-operative treatment with arm immobilised to a sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dutasteride Capsules in Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride-Test product|DRUG: Dutasteride-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Duloxetine and Innovative Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence in Women
Interventions: BEHAVIORAL: Pelvic floor muscle training (PFMT) with lumbopelvic stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Valsartan/Amlodipine (EXforge®) and Nifedipine treAtment coMparison in Treating Chinese Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Valsartan/Amlodipine|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Anastomosis Versus Enterostomy in the Surgical Treatment of Necrotising Enterocolitis
Status: RECRUITING
Conditions: Necrotizing Enterocolitis
Interventions: PROCEDURE: Primary anastomosis|PROCEDURE: Enterostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: BEHAVIORAL: Social Skills and Neurocognitive Individualized Training (SoCIAL)|OTHER: Treatmment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study To Assess The Efficacy And Safety Of The Medical Device Iracross Versus Iraline Administered Intra-Articular To Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Iracross|DEVICE: Iraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)
Status: RECRUITING
Conditions: Asthma|COPD
Interventions: DRUG: n-acetylcystine (NAC)+ albuterol|DEVICE: AeroEclipse-VersaPAP System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Are Opioids Needed After ACL Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: DRUG: Oxycodone|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maxigesic 325 Acute Dental Pain Study
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Maxigesic 325|DRUG: Acetaminophen|DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Evaluating Agents Stimulants Erythropoiesis (ASE) Associated With Ferric Carboxymaltose (Ferinject ®) in Concomitant or Sequential Patients Treated for Cancer and With Anemia Associated With Functional Iron Deficiency
Status: TERMINATED
Conditions: Solid Cancer Metastatic Disease|Lymphoid Disease
Interventions: DRUG: ARM A : IV iron + epoietin zeta|DRUG: ARM B: IV iron + epoietin zeta sequence|DRUG: ARM C : single epoietin zeta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Double Checkpoint Inhibition
Status: RECRUITING
Conditions: Leptomeningeal Metastasis|Non-small Cell Lung Cancer Stage IV|Melanoma Stage IV
Interventions: DRUG: intrathecal nivolumab and intrathecal ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: 18F-FFNP|DEVICE: CTI/Siemens Biograph 40 PET/CT Scanner|DRUG: Estradiol|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IOBT Versus IO-Rec for Hypertropia With IOOA (IIHIOOA)
Status: RECRUITING
Conditions: Hypertropia|Inferior Oblique Overaction
Interventions: PROCEDURE: IOBT|PROCEDURE: IO-Rec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and A Second Controller Medication (VERSE)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: lebrikizumab|DRUG: lebrikizumab|DRUG: lebrikizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: F-18-PSMA-1007 Versus F-18-Fluorocholine PET in Patients With Biochemical Recurrence
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Cancer Recurrent
Interventions: DRUG: F-18-PSMA-1007|DRUG: F-18-Fluorocholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Adjuvant Therapy for High-Risk Breast Cancer With Wkly Adriamycin & Oral Cytoxan With G-CSF for 12 Wks; Wkly Taxol x 12
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PMCF Investigation on Exuding Chronic Wounds Using Exufiber® as Primary Dressing, and Mepilex® Border Flex/Comfort
Status: TERMINATED
Conditions: Wound Heal
Interventions: DEVICE: Exufiber® and Mepilex® Border Flex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Miltefosine for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia
Status: UNKNOWN
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Miltefosine|DRUG: Meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Lateral wedge orthotic shoe inserts|DEVICE: Standard orthotic shoe inserts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Egg Versus Whey Protein Powder During Resistance Training
Status: COMPLETED
Conditions: Muscle Atrophy
Interventions: DIETARY_SUPPLEMENT: Whole egg powder|DIETARY_SUPPLEMENT: Whey protein powder|DIETARY_SUPPLEMENT: Maltodextrin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Premixed Verses Powder/Liquid Bioceramic MTA in Indirect Pulp Capping.
Status: NOT_YET_RECRUITING
Conditions: Indirect Pulp Capping
Interventions: OTHER: Premixed MTA|OTHER: Powder/liquid MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Clinical Trial With Rituximab (MabThera ®) in Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Combining Speech Therapy With a Non-invasive Brain Stimulation (tDCS) for the Aphasic Patient
Status: UNKNOWN
Conditions: Aphasia
Interventions: PROCEDURE: improvement of language for aphasics patients|DEVICE: Sham tDCS|DEVICE: tDCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Interventions: DRUG: SAR443820|DRUG: SAR443820|DRUG: Erythromycin ethyl succinate|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: detached mindfulness|BEHAVIORAL: cognitive restructuring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bolus Versus Continuous Feeding Regimens Post Gastrostomy Tube Placement
Status: TERMINATED
Conditions: Enteral Nutrition|Enteral Feeding|Gastrostomy Tube
Interventions: PROCEDURE: Bolus feeding schedule following gastrostomy tube placement|PROCEDURE: Continuous chimney feeds following gastrostomy tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacological Intervention for Symptomatic Snoring
Status: COMPLETED
Conditions: Snoring
Interventions: DRUG: SAS2094AH and SAS2094BH|DRUG: SAS2094AL and SAS2094BL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Topical Palmitoylethanolamide (PEA) Formulation (Levagen+) for Reducing Symptoms of Eczema
Status: COMPLETED
Conditions: Eczema, Atopic
Interventions: DRUG: 1.5% Palmitoylethanolamide (PEA) sold as Levagen+|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Transnasal Humidified Rapid-insufflation Ventilatory Exchange During Laryngeal Microsurgery
Status: COMPLETED
Conditions: Apneic Oxygenation
Interventions: PROCEDURE: endotracheal intubation|PROCEDURE: high flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 0822GCC: Phase 2 Study of Efficacy and Safety of Apricoxib/Placebo With Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: apricoxib|DRUG: Placebo|DRUG: Docetaxel or Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Autotransplantation in Quadriceps Femoris Muscle
Status: UNKNOWN
Conditions: Thyroid
Interventions: PROCEDURE: Throid autotransplantation|DRUG: Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Physical Exercise Program in Hematopoietic Stem Cell Transplantation Recipients
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: BEHAVIORAL: Ambulatory Physical Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aurora A Kinase Inhibitor MLN8237 and Bortezomib in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: Aurora A kinase inhibitor MLN8237|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab Combined With PDT Versus Bevacizumab to Treat Exudative AMD
Status: UNKNOWN
Conditions: Macular Degeneration
Interventions: DRUG: bevacizumab|DRUG: vetaporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of High-flow Nasal Oxygenation on Gastric Insufflation in Children
Status: NOT_YET_RECRUITING
Conditions: Induction of General Anesthesia
Interventions: DEVICE: HFNO group|DEVICE: MV group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Inflammatory Bowel Disease : Could a Regular Physical Activity Reduce Patients Fatigue ?
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease
Interventions: OTHER: regular and moderate physical activity|OTHER: No regular and moderate physical activity more than usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Accumulation of Dietary Bioactives and Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Allin|DIETARY_SUPPLEMENT: Sulforaphane|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Phase I Study of DNA Vaccine OC-007 as a Booster Dose of COVID-19 Vaccine
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection|COVID-19 Vaccine Adverse Reaction
Interventions: BIOLOGICAL: DNA vaccine OC-007|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Beverage Comprised of Compounds From Olives on Post-prandial Blood Glucose Responses in Healthy Volunteers
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: OTHER: Control (study 1)|OTHER: Test (study 1)|OTHER: Control (study 2)|DIETARY_SUPPLEMENT: Test (study 2)|OTHER: Control (study 3)|DIETARY_SUPPLEMENT: Test (study 3)|OTHER: Control (study 4)|DIETARY_SUPPLEMENT: Test (study 4)|OTHER: Control (study 5)|OTHER: Test (study 5)|OTHER: Control (study 6)|OTHER: Test (study 6)|OTHER: Control (study 7)|OTHER: Test (study 7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Use of PPSB-SD and VP-VI in Patients With Anticoagulant Therapy and Undergoing Acute CPB Surgery
Status: COMPLETED
Conditions: CPB|Oral Anticoagulant Therapy
Interventions: DRUG: PPSB-SD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Plus Etoposide and Platinum-based Chemotherapy for Genitourinary Small Cell Carcinoma
Status: RECRUITING
Conditions: Toripalimab|First-line Treatment
Interventions: DRUG: EP/EC+PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunological Response After Ablative Therapy in the Liver
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Immune Response
Interventions: DEVICE: Microwave ablation|DEVICE: Irreversible electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Metastatic Cutaneous Melanoma|Metastatic Mucosal Melanoma|Metastatic Non-Cutaneous Melanoma|Non-Cutaneous Melanoma|Recurrent Cutaneous Melanoma|Recurrent Mucosal Melanoma|Recurrent Non-Cutaneous Melanoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|BIOLOGICAL: Recombinant Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Neurofeedback Training of Fronto-limbic Regions Functional Connectivity
Status: RECRUITING
Conditions: Emotion Regulation|Healthy
Interventions: DEVICE: Real-time fMRI neurofeedback from Turbo Brain voyager (TBV) 3.2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mini-invasive Preventive Fixation of the Contralateral Femoral Neck in Patients Operated on for a Femoral Neck Fracture
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures
Interventions: DEVICE: Preventive fixation of the contralateral femoral neck (Stryker Trauma and Depuy Synthes screws)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer|Lymphoma
Interventions: DEVICE: PARASYM neuromodulation device|DEVICE: PARASYM neuromodulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prophylactic Negative Pressure Dressings for Closed Laparotomy Wounds - A Randomised, Controlled, Open Label Trial
Status: COMPLETED
Conditions: Infection
Interventions: DEVICE: Negative pressure dressing|DEVICE: Standard wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Status: WITHDRAWN
Conditions: Sprain
Interventions: DRUG: Ketoprofen 10% cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Playing Super U on Pre-adolescents' Body Image
Status: COMPLETED
Conditions: Body Image
Interventions: BEHAVIORAL: Super U Story intervention|BEHAVIORAL: Alternative Roblox game|BEHAVIORAL: Online word search
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Training in the Situation Background Assessment Recommendation (SBAR) Tool on the Feeling of Self-efficacy of Carers of Patients With Lung Cancer in the Face of a Situation of Simulated Respiratory Distress.
Status: NOT_YET_RECRUITING
Conditions: Caregivers
Interventions: OTHER: SBAR training by serious game
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy on Exercise Tolerance of Symbicort (Budesonide/Formoterol) Compared to Placebo and Oxis in Patients With Severe COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: budesonide/formoterol Turbuhaler 320/9µg|DRUG: formoterol Turbuhaler 9µg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Pro-ischaemic Effects of Air Pollution Exposure Using a Simple Face Mask
Status: COMPLETED
Conditions: Angina Pectoris|Coronary Heart Disease|Blood Pressure|Heart Rate Variability
Interventions: DEVICE: No Face Mask|DEVICE: Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multi-day Doses in Prevention of Nausea and Emesis
Status: COMPLETED
Conditions: Myeloma, Plasma-Cell|Lymphoma, Malignant
Interventions: DRUG: Palonosetron|DRUG: Aprepitant|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tranexamic Acid Versus Blood Stopper Treatments in Epistaxis Management
Status: NOT_YET_RECRUITING
Conditions: Epistaxis Nosebleed
Interventions: DRUG: Blood Stopper (Ankaferd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Social and Professional Reintegration Improvements Using a Set of Solutions for Upper Limb Amputation
Status: UNKNOWN
Conditions: Amputation; Traumatic, Arm, Upper|Amputation; Traumatic, Arm: Forearm|Amputation; Traumatic, Hand, at Wrist Level|Wounds and Injuries
Interventions: DEVICE: ORTHOPUS prosthetic accessory: 0109 - Universal Wrist|DEVICE: ORTHOPUS prosthetic terminal device: 0112 - Hook|DEVICE: ORTHOPUS prosthetic terminal device: 0105 - Cosmetic Articulated Hand|DEVICE: ORTHOPUS prosthetic accessory: 0104 - body powered harness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of Novel Treatment Algorithms
Status: RECRUITING
Conditions: Prostate Cancer|Metastatic Prostate Cancer
Interventions: COMBINATION_PRODUCT: Standard of Care|PROCEDURE: Minimally Invasive Ablative Therapy (MIAT)|PROCEDURE: Radical Therapy (Prostatectomy or Radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficiency of Neurostimulation of Tibial Nerve in the Treatment of Low Anterior Resection Syndrome
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DEVICE: Posterior tibial nerve stimulation|DEVICE: Sham posterior tibial nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Pharmacodynamics of Caspofungin (Cancidas ®) and Drug Tolerance of Fungi to Patients With an Invasive Fungal Infection in the Intensive Care Unit
Status: UNKNOWN
Conditions: Invasive Fungal Infection
Interventions: DRUG: Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Paliperidone Palmitate in the Prevention of Relapse of the Symptoms of Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizoaffective Disorder
Interventions: DRUG: Placebo|DRUG: paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Injection of Mitomycin C for the Treatment of Pharyngoesophageal Stenosis
Status: TERMINATED
Conditions: Esophageal Stenosis|Deglutition Disorders|Head and Neck Neoplasms|Esophageal Neoplasms
Interventions: DRUG: Endoscopic injection of Mitomycin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging (MRI) in Patients With Pacemakers and Implanted Cardioverter Defibrillators
Status: ENROLLING_BY_INVITATION
Conditions: Device:MRI
Interventions: DEVICE: Device: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Eye Drop Dispensers: Safety, Efficacy and Comfort.
Status: UNKNOWN
Conditions: Glaucoma|Cataract|Healthy Subjects
Interventions: DEVICE: Eye Drop Dispenser TYPE Opticare|DEVICE: Eye Drop Dispenser Autodrop
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modification of Extracorporeal Photopheresis in Cutaneous T-cell Lymphoma or Chronic Graft-versus-host Disease
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma, Unspecified|Chronic Graft Versus Host Disease in Skin
Interventions: DRUG: ECP with 5-aminolevulinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Functional Abdominal Pain Syndrome|Child|Adolescent|Therapeutics|Adverse Drug Event
Interventions: DRUG: Small intestinal release peppermint oil|DRUG: Peppermint sweets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMpact of Perineural Hydrodissection Over Alternative Therapies in Patients With Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Perineural Hydrodissection|PROCEDURE: Corticosteroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sudarshan Kriya Yoga (SKY) in Post Traumatic Stress Disorder: a Feasibility Study
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: OTHER: Sudarshan Kriya Yoga Tauma Relief Program (SKY).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Renal Autologous Cell Therapy (REACT) in Participants With Type 2 Diabetes and Chronic Kidney Disease
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Diseases
Interventions: BIOLOGICAL: Renal Autologous Cell Therapy (REACT)|PROCEDURE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heterodyned Whole-Body Vibration in Treatment of Opioid Withdrawal-Induced Anxiety
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DEVICE: HWBV chair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT