pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Influence Instillation Plasma Rich in Growth Factors in Endometrial Cavity Endometrial Development in Assisted Reproduction.
Status: TERMINATED
Conditions: Endometrial Development
Interventions: DRUG: Growth Factor, Platelet-Derived
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pk Study in 1- to 3- Month-Old Children With Bronchiolitis (0476-297)
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: MK0476, Montelukast Sodium /Duration of Treatment : 14 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Miniscrew-assisted Rapid Palatal Expansion With and Without Corticopuncture
Status: UNKNOWN
Conditions: Palatal Expansion Technique|Posterior Crossbite|Maxillary Hypoplasia|Malocclusion
Interventions: PROCEDURE: MARPE with Corticopunctures|DEVICE: MARPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evidence of Robot Guided vs. Navigated vs. Free Hand Lumbar Spinal Fusion
Status: WITHDRAWN
Conditions: Spondylolisthesis|Intervertebral Disc Degeneration
Interventions: PROCEDURE: Pedicle Screw Placement|DEVICE: SpineAssist®/Renaissance® (Mazor Robotics Ltd. Caesarea, Israel)|DEVICE: 3D C-Arm (Ziehm Imaging, Nuremberg, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cyclosporine A Microemulsion in Maintenance Patients With Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Cyclosporine A microemulsion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ten-Weeks Progressive Resistance Training on Neuromuscular Performance, Mobility, Heart Rate Variability and Sleep Quality in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Physical exercise|OTHER: Testing sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Antiphospholipid Antibodies on Thrombin Generation During Sars-CoV2 Infection (TACIT2 Study)
Status: NOT_YET_RECRUITING
Conditions: Antiphospholipid Syndrome|COVID-19
Interventions: DIAGNOSTIC_TEST: characterization of aPL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Cognitive-Affective Behavior Therapy for the Treatment of Somatization Disorder
Status: COMPLETED
Conditions: Somatization Disorder
Interventions: BEHAVIORAL: Augmented Standard Medical Care|BEHAVIORAL: Cognitive-Affective Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of CanChew® Cannabidiol (CBD) Containing Chewing Gum on Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: CBD chewing gum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of First Line Treatment With Avastin (Bevacizumab) in Combination With Carboplatin and Weekly Paclitaxel in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Methods for Postpartum Reduction of Vascular Events: Pilot Randomized Controlled Trial
Status: UNKNOWN
Conditions: Pre-Eclampsia
Interventions: BEHAVIORAL: CardioPrevent® Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interscalene Block With Low-dose IV vs. Perineural Dexamethasone for Shoulder Arthroscopy
Status: COMPLETED
Conditions: Pain|Shoulder Arthroscopy
Interventions: DRUG: Bupivacaine|DRUG: Perineural dexamethasone|DRUG: Intravenous dexamethasone|DRUG: Intravenous saline|DRUG: Perineural saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AUY922 in Metastatic Pancreatic Cancer Who Are Resistant to First Line Chemotherapy
Status: TERMINATED
Conditions: Adenocarcinoma of the Pancreas|Metastatic Disease
Interventions: DRUG: AUY922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: Campath-1H|DRUG: r-ATG|DRUG: CsA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Automated Insulin Pump Settings Using the Advisor Pro (Previously Called) MD-Logic Pump Advisor-three Segments Study
Status: TERMINATED
Conditions: Type 1 Diabetes
Interventions: DEVICE: MD-Logic Pump Advisor|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tafluprost-Timolol Preservative-free Fixed Dose Combination (FDC) Superiority Study Against Monotherapies
Status: COMPLETED
Conditions: Ocular Hypertension|Open-angle Glaucoma
Interventions: DRUG: Timolol/ FDC/ Placebo/ Tafluprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy, Safety and Tolerability in Antiretroviral Therapy (ART)-Experienced Participants of at Least 50 Years of Age Living With Human Immunodeficiency Virus (HIV) With Virologic Suppression Who Switch to DTG/3TC FDC From BIC/FTC/TAF
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|HIV Infections
Interventions: DRUG: DTG/3TC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage 0 Bladder Urothelial Carcinoma|Stage 0is Bladder Urothelial Carcinoma|Stage I Bladder Urothelial Carcinoma
Interventions: BIOLOGICAL: BCG Solution|BIOLOGICAL: BCG Tokyo-172 Strain Solution|BIOLOGICAL: BCG Tokyo-172 Strain Vaccine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: BKM120|DRUG: BKM120 matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Adjuvant Therapy on Post-menopausal Women With Breast Cancer Under the Guidance of the Results of Preoperative Endocrinotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: AI adjuvant therapy|DRUG: AI+chemotherapy adjuvant therapy|DRUG: AI adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Saccharomyces Cerevisiae in LDL Cholesterol
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Saccharomyces cerevisiae|DIETARY_SUPPLEMENT: Lynside Wall Basic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of the Efficacy and Safety of Topical Nitric Oxide in Patients With Anogenital Warts
Status: COMPLETED
Conditions: Anogenital Warts|Condylomata Acuminata
Interventions: DRUG: Topical NO|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: APF530|DRUG: dexamethasone|DRUG: Palonosetron Hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes of Bone Metabolic Markers and Bone Mineral Density After Denosumab and/or Teriparatide Treatment in Japanese Osteoporotic Patients
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Denosumab treatment in osteoporotic patients|DRUG: Teriparatide treatment in osteoporotic patients|DRUG: Denosumab and teriparatide treatment in osteoporotic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Loop Control in Adolescents Using Heart Rate as Exercise Indicator
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: heart rate Control to Range System (hrCTR) using DiAs Platform|OTHER: DiAs Control-to-Range System not informed for heart rate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Investigate Pharmacokinetics and Pharmacodynamics of CJ-12420 After Single and Multiple Dose Administration
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ-12420 50mg(HP-)|DRUG: CJ-12420 100mg(HP-)|DRUG: CJ-12420 50mg(HP+)|DRUG: CJ-12420 100mg(HP+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Empagliflozin on Clinical Outcomes in Patients With Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure Acute|Heart Failure，Congestive|Heart Failure; With Decompensation
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CM350 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: CM350_group 1|DRUG: CM350_group 2|DRUG: CM350_group 3|DRUG: CM350_group 4|DRUG: CM350_group 5a|DRUG: CM350_group 5b|DRUG: CM350_group 6a|DRUG: CM350_group 6b|DRUG: CM350_group 7|DRUG: CM350_group 8|DRUG: CM350_MTD level|DRUG: CM350_MTD-1 level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study Describing Conditions for Administering Slow-acting Insulin Analogue With Oral Antidiabetic Agents in Type 2 Diabetes on Blood Glucose Control
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sex Differences in the Response to Abstinence From Alcohol.
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Abstinence from alcohol|BEHAVIORAL: Usual drinking|DRUG: Intravenous Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Coronary CT Angiography Using a Novel 3rd Generation Dual-Source CT System
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Coronary CT angiography on SOMATOM Force|PROCEDURE: Previous coronary CT angiography on 2nd generation CT scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Ventral Rectopexy for Severe Rectal Prolapse
Status: COMPLETED
Conditions: Rectal Prolapse
Interventions: PROCEDURE: LPS Ventral Rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke
Status: COMPLETED
Conditions: Hemiparesis|Stroke
Interventions: BEHAVIORAL: Mirror therapy|BEHAVIORAL: Divider therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Hydromorphone combined with ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Status: COMPLETED
Conditions: Malocclusion, Angle Class II, Division 1
Interventions: BIOLOGICAL: i-PRF|PROCEDURE: canine retraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Test a New Drug to Treat Major Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: GW856553|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Glycemic Index of Diet on Metabolic and Reproductive Parameters in Overweight and Obese Infertile Women
Status: COMPLETED
Conditions: Female Infertility|Obesity
Interventions: OTHER: Low Glycemic Index Diet Group|OTHER: Conventional Diet Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Plasmapheresis
Interventions: PROCEDURE: Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety (Including 24-hour Holter Monitoring) of Tiotropium Inhalation Capsules in Patients With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate Safety and Efficacy of AMB-05X in Subjects With Idiopathic Pulmonary Fibrosis
Status: WITHDRAWN
Conditions: IPF
Interventions: BIOLOGICAL: AMB-05X|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Methods in Finding Lung Cancer Early in Current or Former Smokers
Status: UNKNOWN
Conditions: Lung Cancer|Tobacco Use Disorder
Interventions: OTHER: laboratory biomarker analysis|OTHER: screening questionnaire administration|PROCEDURE: bronchoscopic and lung imaging studies|PROCEDURE: computed tomography|PROCEDURE: endoscopic biopsy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Presbyopia-Correcting Intraocular Lenses (IOLs)
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ReSTOR +3|DEVICE: Crystalens HD|DEVICE: Crystalens AO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Galacto-oligosaccharides and Intestinal Activity
Status: RECRUITING
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Galacto-oligosaccharides|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Urox™ in the Treatment of Overactive Bladder and Urinary Incontinence
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence|Urinary Frequency or Urgency Adverse Event|Nocturia
Interventions: DIETARY_SUPPLEMENT: Urox|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Context Interventions: Social Modeling and Initial Treatment Experience
Status: NOT_YET_RECRUITING
Conditions: Placebo Effect|Pain
Interventions: BEHAVIORAL: Observed Success|BEHAVIORAL: Observed Failure|BEHAVIORAL: Experienced Success|BEHAVIORAL: Experienced Failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation
Status: UNKNOWN
Conditions: Blue Rubber Bleb Nevus Syndrome|Venous Malformation
Interventions: DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TT-4 as a Single Agent in Subjects With Advanced Selected Solid Tumors
Status: UNKNOWN
Conditions: Colorectal Cancer|Gastric Cancer|Hepatocellular Carcinoma|Pancreatic Cancer
Interventions: DRUG: TT-4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IL-6, IL-17 and IL-35 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy Controls
Status: COMPLETED
Conditions: Periodontitis
Interventions: OTHER: No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cisplatin and Nab-paclitaxel for (N2) Defined NSCLC
Status: TERMINATED
Conditions: Stage IIIA Non-Small Cell Lung Cancer
Interventions: DRUG: Neoadjuvant Cisplatin, nab-paclitaxel|DRUG: Adjuvant Cisplatin,nab-paclitaxel|DRUG: Adjuvant cisplatin+pemetrexed or cisplatin+gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pictograms to Facilitate Comprehension of Medical Indications
Status: UNKNOWN
Conditions: Asthma Chronic|Adherence, Medication|Primary Health Care
Interventions: OTHER: SIMAP|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Efficacy of Sequential Rapid Versus Slow Intrathecal Injection Of Dexmedetomidine Followed by of Hyperbaric Bupivacaine in Inguinal Hernia Repair Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Analgesic Efficacy of Sequential Rapid Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine Injection in Patients Undergoing Unilateral Inguinal Hernia Repair|DRUG: Analgesic Efficacy of Sequential Slow Intrathecal Injection Of Dexmedetomidine Followed by Slow Injection of Hyperbaric Bupivacaine in Patients Undergoing Unilateral Inguinal Hernia Repair Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: ReAcT CO2: A Study to Assess TcCO2 to Guide Acute NIV
Status: NOT_YET_RECRUITING
Conditions: Acute Hypercapnic Respiratory Failure
Interventions: DEVICE: Trancutaneous CO2 monitoring (using TCM5 device)|OTHER: Arterial Blood Gas (ABG) sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using Virtual Reality and Sensor Technology to Enhance Outcomes From Treatment for Binge Eating
Status: COMPLETED
Conditions: Binge Eating|Inhibition (Psychology)
Interventions: OTHER: Virtual-reality-based training|OTHER: Inhibitory Control Training|OTHER: Sham Inhibitory Control Training|OTHER: Computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation
Status: UNKNOWN
Conditions: Acute Respiratory Failure|Hypercapnic Respiratory Failure|Respiratory Acidosis|Obesity|Hypoventilation Syndrome|Apnea, Obstructive
Interventions: DEVICE: AVAPS-AE mode during NIV|DEVICE: S/T mode during NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Cerdulatinib Gel, 0.37% in Adults With Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Cerdulatinib 0.37% gel|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ba-Duan-Jin and Pregabalin in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Ba-Duan-Jin|DRUG: Pregabalin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Inhaled Nitric Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21
Status: RECRUITING
Conditions: Malaria, Plasmodium Falciparum
Interventions: BIOLOGICAL: Matrix-M with RH5.2 VLP and/or R21
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Light Therapy and Binge Eating Disorder Treatment (BED Light Study)
Status: COMPLETED
Conditions: Binge-Eating Disorder
Interventions: DEVICE: High intensity bright light therapy|DEVICE: Low intensity light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis
Status: COMPLETED
Conditions: Oestrogen Receptor Positive Advanced Breast Cancer
Interventions: DRUG: RAD001|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Malignant Pleural Effusion|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: imatinib mesylate|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CTX-4430 for the Treatment of Moderate to Severe Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CTX-4430|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Allogenic Mesenchymal Stem Cells to Treat Extensive Chronic Graft Versus Host Disease
Status: UNKNOWN
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Mesenchymal stem cell (MSC)|DRUG: Prednisone and cyclosporine or primary therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Eight-week Randomized,Double-blind Study to Evaluate the Efficacy and Safety of Fixed-dose Combinations of T80+A5 Versus A5 Monotherapy in Patients With Hypertension Who Fail to Respond Adequately to Treatment With A5 Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan80mg+Amlodipine5mg|DRUG: amlodipine 5mg|DRUG: Telmisartan80mg+Amlodipine 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Computer Guided Screw Holes Locating Guide and Custom-made Plates
Status: UNKNOWN
Conditions: Mandibular Fractures
Interventions: PROCEDURE: computer guided screw holes locating guide and custom-made plates|PROCEDURE: conventional plates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Calcium Dobesilate|DRUG: Cabergoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ascending Ramus Versus Chin Cortical Plates for Reconstruction of Atrophic Maxilla
Status: UNKNOWN
Conditions: Atrophy of Edentulous Maxillary Alveolar Ridge
Interventions: PROCEDURE: Atrophic maxillary alveolar ridge augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gadobutrol Enhanced MRA of the Renal Arteries
Status: COMPLETED
Conditions: Renal Artery Obstruction
Interventions: DRUG: Gadobutrol (Gadovist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Curative Effect of Ru-Yi-Jin-Huang-Saan
Status: RECRUITING
Conditions: Colles' Fracture
Interventions: DRUG: Ru Yi Jin Huang Powder|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Method Early Intervention Program for Inhibited and Anxious Preschoolers
Status: COMPLETED
Conditions: Behavioral Inhibition|Anxiety
Interventions: BEHAVIORAL: Parent Psychoeducation|BEHAVIORAL: Turtle Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Acute Coronary Syndromes
Interventions: OTHER: screening test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Extension Protocol for the Extended Use of Talimogene Laherparepvec for Eligible Patients Who Participated in Study 002/03 (NCT00289016)
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ketoconazole|DRUG: therapeutic hydrocortisone|OTHER: Withdrawal of antiandrogen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Stabilization Exercises & (PNF) on Pain, Disability & Functional Leg Length
Status: RECRUITING
Conditions: Anterior Innominate Iliosacral Dysfunction
Interventions: OTHER: Proprioceptive neuromuscular facilitation|OTHER: Pelvic stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Immune Health by Intermittent Fasting: a Pilot Study
Status: RECRUITING
Conditions: Metabolic Syndrome|HEALTHY VOLUNTEERS|Time Restricted Feeding|Insulin Resistance|Inflammation
Interventions: COMBINATION_PRODUCT: Time Restricted Eating|OTHER: normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: ifosfamide|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics
Status: COMPLETED
Conditions: Adult ALL|Healthy
Interventions: DEVICE: Medial or Lateral Wedge|DEVICE: Carbon Fiber Custom Dynamic Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Pilot Study on the Use of Prophylactic Antibiotics for EUS-guided Pancreatic Cyst Aspiration
Status: COMPLETED
Conditions: Pancreatic Cysts
Interventions: DRUG: Ciprofloxacin|OTHER: Placebo (for ciprofloxacin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule
Status: COMPLETED
Conditions: Vascular Dementia
Interventions: DRUG: SaiLuoTong capsule|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Oxygenation to Guide Medical Interventions in Extremely Preterm Infants
Status: COMPLETED
Conditions: Premature Infants|Near-infrared Spectroscopy|Oximetry
Interventions: DEVICE: cerebral oximeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydrogen-rich Water and Treatment of Mucositis Caused by Radiation Therapy in Head and Neck Cancer Patients
Status: RECRUITING
Conditions: Mucositis Oral
Interventions: DIETARY_SUPPLEMENT: Hydrogen tablets|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elotuzumab and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Cell Transplantation Recipient|Plasma Cell Myeloma
Interventions: BIOLOGICAL: Elotuzumab|DRUG: Lenalidomide|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
Status: UNKNOWN
Conditions: COVID|Corona Virus Infection|Acute Lung Injury|Ischemia Limb|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Remote Ischemic Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Semaglutide in Systemic Scleroderma
Status: RECRUITING
Conditions: Scleroderma, Systemic|Fibrosis|Semaglutide
Interventions: DRUG: Semaglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationships Between Physical Activity and Inhibitory Control Among College Students
Status: NOT_YET_RECRUITING
Conditions: Cognition
Interventions: BEHAVIORAL: Moderate-intensity cycling|BEHAVIORAL: Vigorous-intensity cycling|BEHAVIORAL: Uninterrupted sitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite)
Status: COMPLETED
Conditions: Edematous Fibrosclerotic Panniculopathy|Cellulite
Interventions: BIOLOGICAL: Collagenase Clostridium Histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain and Polyamines-poor Diet (DOLAMINE)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: poor-polyamines diet|OTHER: high polyamines diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevent Postpartum Hemorrhage in Women With Von Willebrand Disease: The VWD-WOMAN Trial
Status: RECRUITING
Conditions: Von Willebrand Diseases|Postpartum Hemorrhage
Interventions: DRUG: Recombinant Von Willebrand factor|DRUG: Tranexamic Acid Injection [Cyklokapron]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Septal Ablation for Obstructive HCM
Status: RECRUITING
Conditions: Hypertrophic Obstructive Cardiomyopathy (HOCM)
Interventions: DEVICE: percutaneous intramyocardial septal radiofrequency ablation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA
Status: RECRUITING
Conditions: Osteo Arthritis Knee|Knee Pain Chronic
Interventions: PROCEDURE: Diagnostic genicular nerve block|PROCEDURE: Genicular nerve block with Radiofrequency Ablation (RFA)|PROCEDURE: Genicular nerve block with Phenol 6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Dietary Supplements on Height Improvement in Children
Status: RECRUITING
Conditions: Body Height|Child, Only
Interventions: DIETARY_SUPPLEMENT: Buckwheat|DIETARY_SUPPLEMENT: Astragalus extract|DIETARY_SUPPLEMENT: Wolfiporia extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With Etanercept
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Healthy
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic on Insulin Resistance in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type2 Diabetes|Insulin Resistance|Probiotic
Interventions: DIETARY_SUPPLEMENT: probiotic|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Ripple Mapping to Guide Substrate Ablation of Scar Related Ventricular Tachycardia.
Status: WITHDRAWN
Conditions: Monomorphic Ventricular Tachycardia|Myocardial Infarction|Dilated Cardiomyopathy
Interventions: DEVICE: Ripple Mapping guided VT ablation|DEVICE: Conventional VT ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block: A Breakthrough Treatment for Post-Stroke Pharyngeal Dysphagia
Status: TERMINATED
Conditions: Dysphagia|Stellate Ganglion Block
Interventions: BEHAVIORAL: comprehensive rehabilitation|DRUG: SGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Characterization of the Active, Separated System With PK Controller (Fentanyl Iontophoretic Transdermal System, 40 Mcg Fentanyl Per Activation).
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Fentanyl|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Dexmedetomidine and Dexamethasone as an Adjuvant to Ropivacaine in Thoracic Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative|Oxidative Stress
Interventions: DRUG: Dexmedetomidine Injection [Precedex]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With Clopidogrel
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DRUG: Fentanyl|DRUG: Propofol|DRUG: Rocuronium|DRUG: Chirochaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: MK0954A-264 Filter Study (0954A-264)(COMPLETED)
Status: COMPLETED
Conditions: Mild to Severe Hypertension
Interventions: DRUG: MK0954A, hydrochlorothiazide (+) losartan potassium / Duration of Treatment: 6 weeks|DRUG: losartan / Duration of Treatment: 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers
Status: UNKNOWN
Conditions: Wound of Skin|Burns
Interventions: DRUG: KeraStat® Gel with Morphine application|DRUG: KeraStat® Gel application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Osmotic Release Oral Delivery System Methylphenidate (OROS MPH) Upon Family of Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: OROS Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Treatment in a Breast Cancer Population. PaiNEd Study.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Multimodal rehabilitation program + PNE (Therapeutic exercise, manual therapy and PNE)|OTHER: Multimodal rehabilitation program + traditional biomedical information|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Role of the Cervical Spine in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndromes
Interventions: OTHER: Physical Therapy Group|PROCEDURE: Surgical Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Caries Risk Using Propolis-containing Versus Fluoride-containing Toothpastes in High Caries Risk Patients
Status: UNKNOWN
Conditions: Risk Reduction
Interventions: DRUG: propolis-containing toothpaste|DRUG: Fluoride-containing toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of e-Audiology for Providing Clinical Services and Support
Status: COMPLETED
Conditions: Hearing Loss, Age-Related|Presbycusis, Bilateral|Hearing Disability
Interventions: DEVICE: Delivery of hearing healthcare through eAudiology application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of CAT-8015 Immunotoxin in Patients With CLL, PLL or SLL With Advance Disease
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: Immunotoxin therapy|DRUG: CAT-8015 immunotoxin|PROCEDURE: Biological therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Screening of the Status of the Vascular System: Feasibility Test
Status: UNKNOWN
Conditions: To Evaluate the Validity of the Measure Method, we Will Compare Vasculight v1.0 PWV Measures With Those Obtained From E-tracking (Echocardiographic Method).
Interventions: DEVICE: Vasculight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety and Efficacy of Early, seQUential Oral dIuretic Nephron blockAde In Acute Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Acute Heart Failure
Interventions: DRUG: Standard diuretic therapy|DRUG: Early sequential nephron blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
Status: COMPLETED
Conditions: Cryopyrin-associated Periodic Syndromes|Familial Cold Autoinflammatory Syndrome|Muckle-Wells Syndrome|Neonatal Onset Multisystem Inflammatory Disease
Interventions: DRUG: ACZ885
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Two Weeks of 5:2 Intermittent Energy Restriction on Basal and Postprandial Metabolism
Status: COMPLETED
Conditions: Weight Loss
Interventions: OTHER: 5:2 Intermittent energy restriction|OTHER: Continuous energy restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Prostaglandin I2 on the Endothelial Cell Function Disorder in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Peripheral Microvascular Symptoms
Interventions: DRUG: Prostaglandin I2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Two Fixed-dose Combinations of Aclidinium Bromide With Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium 400 μg / Formoterol 12 μg|DRUG: Aclidinium 400 μg / Formoterol 6 μg|DRUG: Aclidinium 400 μg|DRUG: Formoterol 12 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Air-Q® SP Versus Air-Q® and I-gel: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Laryngeal Masks
Interventions: DEVICE: air-Q SP|DEVICE: air-Q|DEVICE: i-gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D Vitamin Intervention in VA
Status: COMPLETED
Conditions: Impaired Fasting Glucose|Impaired Glucose Tolerance|Vitamin D Insufficiency
Interventions: DRUG: Placebo|DRUG: 50K vitamin D2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Establishing Clinical Utility of a New Diagnostic Test for Rheumatology Patients
Status: COMPLETED
Conditions: Lupus Nephritis|Lupus Erythematosus, Systemic
Interventions: OTHER: Experimental - Test Results and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC