pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility of Short-Term PrEP Uptake for MSM With Episodic High-Risk for HIV
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: emtricitabine/tenofovir|BEHAVIORAL: CBT-based counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Apneic Oxygenation Including Precipitous Intubations During RSI in the ED
Status: TERMINATED
Conditions: Apneic Oxygenation|Endotracheal Intubation
Interventions: OTHER: Apneic oxygenation during endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Single Ascending Dose Safety Study of TNX-201 Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TNX-201 35 mg|DRUG: TNX-201 70 mg|DRUG: TNX-201 140 mg|DRUG: Racemic isometheptene 70 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of 4-weeks Treatment of BIBW 2948 BS in Patients With Chronic Obstructive Bronchitis
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive|Bronchitis, Chronic
Interventions: DRUG: BIBW 2948 BS
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Influenza Vaccine (Split Virion, Inactivated) Northern Hemisphere 2009-2010 Formulation
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza virus (split virion, inactivated) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dimethyl Fumarate for the Treatment of Intracerebral Hemorrhage
Status: WITHDRAWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Dimethyl fumarate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consultations Reason for Genital, Urinary or Psychological Humans in General Practice
Status: TERMINATED
Conditions: Premature Ejaculation
Interventions: OTHER: Questionary SF12 and PEDT (Premature Ejaculation Diagnostic Tool)|OTHER: Total attention|OTHER: Humour|OTHER: Take the drama out|OTHER: Question about premature ejaculation|OTHER: Symptoms of premature ejaculation|OTHER: Help to verbalize
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Solid Tumor|Recurrent Solid Tumor|Advanced Solid Tumor|Urinary Bladder Neoplasm|Triple Negative Breast Cancer|Non-small Cell Lung Cancer|Esophageal Cancer|Pancreatic Cancer|Ovarian Cancer|Cervical Cancer|Head and Neck Squamous Cell Carcinoma|Prostate Cancer|Renal Pelvis Cancer|Bladder Cancer
Interventions: DRUG: LY4101174
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Success Rate and Acceptability of Conventional and Modified Hall Crowns Among Children and Parents
Status: ACTIVE_NOT_RECRUITING
Conditions: Paediatric Dentistry|Dental Caries in Children|Dental Treatment
Interventions: PROCEDURE: Hall Crown Technique|PROCEDURE: Modified Hall Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)
Status: COMPLETED
Conditions: Hereditary Inclusion Body Myopathy|GNE Myopathy|Nonaka Disease|Quadriceps Sparing Myopathy (QSM)|Distal Myopathy With Rimmed Vacuoles (DMRV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positive Psychotherapy-Based Counseling (PPT)
Status: UNKNOWN
Conditions: Chronic Urticaria|Anxiety
Interventions: BEHAVIORAL: Positive Psychotherapy Based Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia;Schizoaffective
Interventions: OTHER: Active TDCS|OTHER: Sham TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis|Knee Osteoarthritis|Knee Arthritis|Knee Discomfort|Knee Pain Swelling|Knee Pain Chronic
Interventions: DIETARY_SUPPLEMENT: undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Glucagon-Like Peptide 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-cathartic Computed Tomographic Colonography to Screen Subjects With a Family History of Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasia
Interventions: RADIATION: CT colonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma
Status: RECRUITING
Conditions: Undifferentiated Pleomorphic Sarcoma|Myxofibrosarcoma
Interventions: BIOLOGICAL: CAB-AXL-ADC|BIOLOGICAL: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nasal-alar Elevator Combined With Taping Vs. Taping Alone on Improving the Nose Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate
Status: COMPLETED
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Nasal Elevator|DEVICE: Taping Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Comparison Between Single Incision Laparoscopic Cholecystectomy and Standard Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystectomy, Laparoscopic
Interventions: PROCEDURE: Standard laparoscopic cholecystectomy|PROCEDURE: Single incision laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of BMS-955176 on Pharmacokinetics of Dolutegravir and the Effect of Dolutegravir on the Pharmacokinetics of BMS-955176
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Dolutegravir|DRUG: BMS955176
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Carboplatin and Eribulin Mesylate in Triple Negative Breast Cancer Patients
Status: UNKNOWN
Conditions: Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Male Breast Cancer|Progesterone Receptor-negative Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Triple-negative Breast Cancer
Interventions: DRUG: eribulin mesylate|DRUG: carboplatin|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus, SLE
Interventions: DRUG: PIT565
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Benefits of the HyperQTM System in ECG Stress Testing
Status: UNKNOWN
Conditions: Myocardial Ischemia
Interventions: DEVICE: Excercise stress test with high frequency ECG recording (HyperQ™ System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study in Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Glargine|DRUG: LY2605541|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Dopamine Receptor Modulation With Rotigotine to Enhance Morphine Analgesia in the Dental Model
Status: UNKNOWN
Conditions: Post-op Pain
Interventions: DRUG: Neupro® transdermal patch/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Asciminib|DRUG: Bosutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of 99mTC-EC-DG SPECT/CT Versus PET/CT in Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: (99m Tc) ECDG (Ethylenedicysteine-Deoxyglucose)|DRUG: 18 F FDG followed by PET/CT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Plasma Rich in Growth Factors in Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Rotator Cuff Tendinopathy
Interventions: BIOLOGICAL: Plasma rich in growth factors (PRGF)|DRUG: Celestone cronodose (Bethametasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients With Newly Diagnosed Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: Exenatide or metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase1 Study of GR121167, Single and Multiple Dose Study in Healthy Japanese Males
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: GR121167 Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Naltrexone SR/Bupropion SR Trilayer Tablets From Two Manufacturers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Reference naltrexone 8 mg SR/bupropion 90 mg SR combination trilayer tablets (2 tablets)|DRUG: Test naltrexone 8 mg SR/bupropion 90 mg SR combination trilayer tablets (2 tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Lovaza® and Microvascular Function in Type 2 Diabetes
Status: COMPLETED
Conditions: Hypertriglyceridemia|Diabetic Neuropathy
Interventions: DRUG: omega-3-ethyl esters|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of ND-003 in Patients With Advanced Solid Cancers
Status: ENROLLING_BY_INVITATION
Conditions: Advanced Solid Tumor
Interventions: DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets|DRUG: ND-003 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Booster Administration of GAD-alum (Diamyd®) in Individuals With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: GAD-alum (Diamyd) 40 μg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma|Endometrial Carcinoma|Prostate Carcinosarcoma
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|OTHER: Counseling|PROCEDURE: Therapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium
Status: NOT_YET_RECRUITING
Conditions: Anticholinergic Toxicity
Interventions: DRUG: Rivastigmine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Regain After Bariatric Surgery and Web-Based Interactive Nurse Support Program: Mixed Methods Research
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate
Interventions: BEHAVIORAL: Web-Based Interactive Nurse Support Program Based on Health Promotion Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Acute Rhino-Sinusitis With Essential Oils of Aromatic Plants
Status: COMPLETED
Conditions: Rhino-Sinusitis
Interventions: DIETARY_SUPPLEMENT: mixture of aromatic essential oils.|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER)
Status: RECRUITING
Conditions: People With Subjective Cognitive Impairement (SCI)
Interventions: BEHAVIORAL: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sleeve Gastrectomy in Adolescents With Complicated Morbid Obesity and NAFLD
Status: COMPLETED
Conditions: Morbid Obesity|NAFLD
Interventions: PROCEDURE: Laparoscopic Sleeve gastrectomy (LSG)|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask Supreme and I-Gel in Edentulate Geriatric Patients
Status: RECRUITING
Conditions: Airway Morbidity
Interventions: DEVICE: Laryngeal mask Supreme evaluation|DEVICE: i-gel evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-DCFPyL PET/CT in Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: F18-FDG|DEVICE: MRI|DEVICE: CT|DRUG: F18-DCFPyL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Autistic Disorder|Pervasive Development Disorders
Interventions: DRUG: methylphenidate|DRUG: guanfacine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Cytochrome P450 3A4 and 2C8 Substrates in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: LY4100511 (DC-853) Dose 1|DRUG: LY4100511 (DC-853) Dose 2|DRUG: Midazolam|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation
Status: COMPLETED
Conditions: Severe Tricuspid Valve Regurgitation (Disorder)
Interventions: PROCEDURE: Inferior Vena Caval (IVC) Occlusion maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Emtricitabine/tenofovir disoproxil fumarate placebo|DRUG: Tenofovir disoproxil fumarate|DRUG: Tenofovir disoproxil fumarate placebo|DRUG: Tenofovir 1% vaginal gel|DRUG: Tenofovir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Peripheral Defocus on Axial Growth in Hyperopes
Status: COMPLETED
Conditions: Hyperopia|Amblyopia|Anisohyperopia
Interventions: DEVICE: Multifocal contact lenses|DEVICE: Single vision contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Assessment of Feasibility of Non-invasive Multiple Sensor Hypo-Sense as a Tool for Detection of Hypoglycemia
Status: COMPLETED
Conditions: Type 1 Diabetes|Nocturnal Hypoglycemia
Interventions: DEVICE: Hypo-Sense (non invasive sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of LMWH in Healthy Subjects Treated With TB-402 and Effects of TB-402 in Healthy Subjects Treated With Warfarin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LWMH in TB-402 treated subjects or TB-402 in warfarin treated subjects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy of Long-acting Repeatable Octreotide Acetate for Injectable Suspension vs. Surgery in Treatment-naïve Patients With Acromegaly
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Octreotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follicle-Stimulating Hormone (FSH) and the Onset of Puberty
Status: COMPLETED
Conditions: Delayed Puberty|Precocious Puberty
Interventions: DRUG: Leuprolide Acetate - Early Puberty Leuprolide Visit|DRUG: Ganirelix - Early Puberty Ganirelix Visit|DRUG: Ganirelix - Delayed Puberty Ganirelix Visit|DRUG: Leuprolide Acetate- Delayed Puberty Leuprolide Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: THOR Study: A Study of Continued Herceptin (Trastuzumab) in Combination With Second Line Chemotherapy in Patients With HER2 Positive Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strawberry Candy Twists as an Alternative Screen for Gestational Diabetes: A Prospective Trial
Status: RECRUITING
Conditions: Gestational Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Standard Glucola GCT|DIETARY_SUPPLEMENT: Twizzlers challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: EOS® Versus Spiral CT Technique for Achieving a Pelvimetry in Suites of Obstructed Labor.
Status: COMPLETED
Conditions: Pregnancy
Interventions: DEVICE: EOS|DEVICE: Spiral CT pelvimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Subcutaneous Administration of TEV-48125 for the Preventive Treatment of Chronic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: TEV-48125|DRUG: TEV-48125 or placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota or Placebo After Antimicrobial Therapy for Recurrent C. Difficile at Home (MATCH)
Status: TERMINATED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Fecal Microbiota Therapy (FMT)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pazopanib As Pre-Surgical Therapy In Treatment-Naive Subjects With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Lung Cancer, Non-Small Cell
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol and Dexmedetomidine Versus a Propofol Only Regimen for Sedation During Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Dexmedetomidine|OTHER: Saline placebo|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Pediatric Participants With Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: Deucravacitinib|OTHER: Placebo matching deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Video-based Education on Anxiety, Pain and Recovery Quality in Patients Undergoing Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: video based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Contraceptive Efficacy/Safety of a Low Dose EE/LNG Transdermal Contraceptive Delivery System
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: AG200-15 (cycles 1-13)|DRUG: Lessina crossover to AG200-15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Effect of JNJ-54861911 on Pharmacokinetics of Cocktail Representatives for Cytochrome P450 (CYP) 3A4, CYP2B6, CYP2C9, and CYP1A2 Substrates
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54861911|DRUG: Caffeine|DRUG: Midazolam|DRUG: Tolbutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and PK/PD of DA-3091 in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: SR-exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fixed Combination of Beclomethasone Dipropionate (BDP) + Formoterol Fumarate (FF) + Glycopyrronium Bromide (GB) (CHF 5993)Administered Via Dry Powder Inhaler (DPI) in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF 5993 DPI|DRUG: CHF5993 pMDI|DRUG: CHF 1535 pMDI|DRUG: Placebo DPI|DRUG: Placebo pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Adding an Adductor Canal Block to a Femoral Triangle Block for Total Knee Replacement
Status: COMPLETED
Conditions: Total Knee Replacements
Interventions: PROCEDURE: Adductor canal block|PROCEDURE: Femoral triangle block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of AZD8965 in Healthy Participants (Including Japanese and Chinese Participants) and an Open-label Cohort to Assess the Effect of Food on the Pharmacokinetics of AZD8965 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: AZD8965|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations
Status: RECRUITING
Conditions: Opioid Use Disorder|Infectious Disease|Risk Reduction Behavior|Substance Use|Substance Abuse|Stimulant Use Disorder
Interventions: BEHAVIORAL: Patient Navigator|BEHAVIORAL: Mobile Health Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Longitudinal Study of ACTEMRA® (Tocilizumab) as Monotherapy in Highly Active NMOSD
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorders|Neuromyelitis Optica|Devic's Disease
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study of Atomoxetine Hydrochloride in the Treatment of Adults With ADHD and Comorbid Social Anxiety Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Comorbid Social Anxiety Disorder
Interventions: DRUG: Atomoxetine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
Status: RECRUITING
Conditions: Crohn Disease|Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: DIAGNOSTIC_TEST: Multispectral Optoacoustic Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Energy Shockwave Therapy for Improving Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: OTHER: Pre-inclusion questionnaires|DRUG: 1 month of PDE5i treatment|OTHER: PDE5i follow-up questionnaires|OTHER: Inclusion questionnaires|DEVICE: 4 weekly LIESWT (Wave 1) with the RENOVA device|DEVICE: 4 weekly sham LIESWT (Wave 1) with the RENOVA device|OTHER: Follow-up questionnaires 1 month after Wave 1|OTHER: Follow-up questionnaires 3 months after Wave 1|DEVICE: 8 bi-weekly LIESWT (Wave 2) with the RENOVA device|OTHER: Follow-up questionnaires 1 month after Wave 2|OTHER: Questionnaires via postal mail|OTHER: Final follow-up questionnaires 12 months after Wave 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Supplements on Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Gastric Cancer|Neoadjuvant Chemotherapy
Interventions: DRUG: live combined Bifidobacteriun, Lactobacillus and Enterococcus capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke
Status: ENROLLING_BY_INVITATION
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic
Interventions: BEHAVIORAL: Frequent PT|BEHAVIORAL: Intense PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour Surgery
Status: WITHDRAWN
Conditions: Gastric Cancer|Pancreatic Cancer|Bile Duct Cancer|Duodenal Cancer
Interventions: DRUG: The marketed product 2-5 MBq/kg 18F-fluorodeoxyglucose|DEVICE: EnLightTM|DEVICE: LightPathTM Imaging System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research Study of a New Medicine (NNC9204-1706) in People With Overweight or Obesity
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC9204-1706|DRUG: Placebo (NNC9204-1706)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, and Tolerability Study of TMC435 in Treatment-naive, Genotype 1 Hepatitis C-infected Participants
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Placebo|DRUG: TMC435|DRUG: Peginterferon alpha-2a or Peginterferon alpha-2b (PegIFNα-2a/b)|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Trial of Locally Developed Ready to Use Therapeutic Food
Status: NOT_YET_RECRUITING
Conditions: Malnutrition Severe
Interventions: DIETARY_SUPPLEMENT: Sharnali 1|DIETARY_SUPPLEMENT: Sharnali 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA-PET Imaging of Salivary Gland Tumours and Other Rare Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Salivary Gland Tumor|Rare Malignant Neoplasm
Interventions: DIAGNOSTIC_TEST: 68-Ga PSMA PET scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of Virtual Reality Based Nasogastric Catheter Application Skills on the Knowledge, Skills and Self-Confidence of Graduate Nursing StudentsGraduate Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Advanced Practice Nursing
Interventions: BEHAVIORAL: virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation to Modulate Top-Down Regulation for Drug Craving in Methamphetamine Use Disorder
Status: COMPLETED
Conditions: Amphetamine Use Disorders
Interventions: DEVICE: Active transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of the Safety, Tolerability and Efficacy of E2007 in Parkinson's Disease Patients With "Wearing Off" Motor Fluctuations and "On" Period Dyskinesias
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: E2007|DRUG: E2007|DRUG: E2007|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
Status: COMPLETED
Conditions: Drug Overdose|Overdose of Beta-adrenergic Blocking Drug
Interventions: DRUG: Glucagon|DRUG: Esmolol|DRUG: Physiologic saline - glucagon dummy|DRUG: Physiologic saline - esmolol dummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing Lymphodepletion to Improve Outcomes in Patients Receiving Cell Therapy With Kymriah
Status: RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Cyclophosphamide|RADIATION: TLI|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With EFP; Cellulite (Stage 2)
Status: COMPLETED
Conditions: Cellulite
Interventions: DRUG: CBL-514 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GnRH Agonist Trigger and Modified Luteal Phase Support, Adding a Bolus of GnRHa at the Time of Implantation - a RCT
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Triptorelin 0.1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Therapeutic Trial for the Prevention of Lymphedema
Status: TERMINATED
Conditions: Lymphedema|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: placebo for study drug|DRUG: (RS)2-(3-benzoylphenyl)-propionic acid|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioactive Phytochemicals From Wheat Bran
Status: COMPLETED
Conditions: Bio-availability of Wheat Bran Phytochemicals in the Human Gut|Bio-availability of Wheat Bran Phytochemicals for the Systemic Circulation
Interventions: OTHER: Visit A high wheat bran|OTHER: Visit B normal wheat bran|OTHER: Follow up normal (8days) and high (1day) bran consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Metastatic Pancreatic Cancer
Interventions: DRUG: Cabozantinib + Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Increasing Doses of BIIL 284 BS in Adult and Pediatric Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: BIIL 284 BS, low dose, pediatric patients|DRUG: BIIL 284 BS, medium dose, pediatric patients|DRUG: BIIL 284 BS, high dose, pediatric patients|DRUG: BIIL 284 BS, low dose, adult patients|DRUG: BIIL 284 BS, medium dose, adult patients|DRUG: BIIL 284 BS, high dose, adult patients|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Diferente Single Doses of BIA 9-1067 and a Single-dose of Immediate-release 100/25 mg Levodopa/Carbidopa
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: BIA 9-1067|DRUG: Placebo|DRUG: Sinemet® 100/25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin in Reduction of Tension II Study
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases
Interventions: DRUG: Acetylsalicylic acid|DRUG: Acetylsalicylic acid lysinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-expanding Nitinol Stents of High vs. Low Chronic Outward Force in De-novo Femoropopliteal Occlusive Arterial Lesions
Status: UNKNOWN
Conditions: Stent Restenosis|Intimal Hyperplasia
Interventions: DEVICE: Pulsar Stent|DEVICE: LifeStent Flexstar Vascular Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CGM Monitoring in T2DM Patients Undergoing Orthopaedic Replacement Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: DEVICE: Dexcom G6 Pro Continuous Glucose Monitor (CGM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of Daikenchuto (TU-100) to Relieve Abdominal Bloating in Female Subjects With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome in Females
Interventions: DRUG: TU-100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Oxycodone for Pain Management for Lower Limb Amputation
Status: RECRUITING
Conditions: Epidural|Oxycodone|Pain|Lower Limb Amputation
Interventions: DRUG: Oxycodone|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation (AF) Patients Not Taking Vitamin-K Antagonist (VKA)
Status: COMPLETED
Conditions: Persistent or Permanent Non-valvular Atrial Fibrillation
Interventions: DRUG: AZD0837|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 3D VOLUMETRIC CHANGE OF THE PALATAL DONOR REGION IN WOUND HEALING
Status: ACTIVE_NOT_RECRUITING
Conditions: Free Gingival Graft Volume Change
Interventions: PROCEDURE: free gingiva graft surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Assessing Pain in the Postoperative Period by Automatically Measuring the Variation Coefficient of Pupillary Diameter: PREVANS Study
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: OTHER: Video-pupillometer|OTHER: Electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Effectiveness of an Immunobiological Drug in CoViD-19
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|COVID-19 Respiratory Infection|Covid19
Interventions: DRUG: Anti-SARS-CoV-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of the Withdrawal of Nitrate in Patients With Stable Angina
Status: COMPLETED
Conditions: Stable Angina|Myocardial Ischemia|Quality of Life
Interventions: DRUG: Nitrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized PEEP Titration on Postoperative Pulmonary Complications
Status: RECRUITING
Conditions: Postoperative Pulmonary Complications|Positive End-expiratory Pressure|Elderly|Laparoscopic Surgery
Interventions: PROCEDURE: Pes-Guided PEEP titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD|HIV/AIDS
Interventions: BEHAVIORAL: Proactive E-consult
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The REbif® vs Glatiramer Acetate in Relapsing Multiple Sclerosis Pharmacogenetics Trial
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: OTHER: Blood sampling|OTHER: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Investigation of the Safety and Efficacy of Renzapride in Constipation Predominant Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Renzapride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo and Active Controlled, Double Dummy Study to Prove Efficacy of Aspirin in Treatment of Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Acetylsalicylic Acid (Aspirin, BAYE4465)|DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Verb Network Strengthening Treatment (VNeST) on Word Finding in Aphasia
Status: TERMINATED
Conditions: Anomia|Aphasia|Stroke
Interventions: BEHAVIORAL: Verb Network Strengthening Treatment (VNeST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effect of Equi-MAC Anesthetics on PSI
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
Status: NOT_YET_RECRUITING
Conditions: Spine Fusion|Spine Injury|Spine Degeneration|Navigation, Spatial
Interventions: PROCEDURE: Spine surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Quality of Recovery Score
Status: COMPLETED
Conditions: Quality of Life|Obstetric Complication|Cesarean Section Complications|Comorbidities and Coexisting Conditions|Obstetric Anesthesia Problems
Interventions: OTHER: Obstetric Quality of recovery score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Trifenatate in the Treatment of Asthma in Adolescent and Adult Subjects of Asian Ancestry.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW685698/GW642444 (fluticasone furoate/vilanterol trifenatate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Propofol Effect-Site Target Controlled Infusion in the Obese: Characterization of the Time Profile of Bispectral Index Response
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laser Versus Mechanical Lithotripsy of Bile Duct Stones
Status: COMPLETED
Conditions: Choledocholithiasis
Interventions: PROCEDURE: Laser and mechanical lithotripsy|PROCEDURE: Mechanical Lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Non ST Segment Elevation Myocardial Infarction|Post MI
Interventions: DRUG: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Individualized Education Using the Teach-Back Method Treatment on Treatment Adherence and the Coping Skills
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: OTHER: Teach-Back Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children
Status: RECRUITING
Conditions: Neuropathic Pain|Chronic Pain
Interventions: DRUG: Capsaicin 8% patch|DEVICE: Hydrocolloid dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microcirculatory Vasomotor Changes in Type 2 Diabetes With Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy Peripheral|Small Vessel Disease of Diabetes Mellitus|Vasodilation|Vasoconstriction
Interventions: OTHER: "Rest"|OTHER: "Exercise"|OTHER: "Foot lowering"|OTHER: "Hyperthermia"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC