pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)
Status: RECRUITING
Conditions: Acute Kidney Injury|Chronic Kidney Diseases|Tomography, Optical Coherence
Interventions: OTHER: Dynamic full-field optical coherence tomography analysis of kidney biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Bariatric Surgery and Pancreas After Kidney Transplantation for Type II Diabetics
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2|Overweight
Interventions: PROCEDURE: Sleeve Gastrectomy AND Pancreas after Kidney Transplantation (Staggered Approach)|PROCEDURE: Combined Sleeve Gastrectomy and Pancreas transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Compound Methyl Salicylate Liniment
Status: COMPLETED
Conditions: Soft Tissue Injuries
Interventions: DRUG: Compound Methyl Salicylate Liniment|DRUG: Diclofenac Sodium Liniment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Protocol of Self-Regulation in Early Learners: The Role of Recreational Programs
Status: COMPLETED
Conditions: Self Regulation|Impulsive|Attention Difficulties|Emotion Regulation
Interventions: BEHAVIORAL: Recreation Activity Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuation of Goal Directed Haemodynamic Optimization in the PACU
Status: COMPLETED
Conditions: Hemodynamic Instability|Postoperative Complications|Ultrasound Imaging
Interventions: OTHER: goal directed intraoperative haemodynamic optimization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Mucosal Resection of Colonic Polyps
Status: WITHDRAWN
Conditions: Colonic Polyps
Interventions: PROCEDURE: Circumferential Submucosal Incision Resection|PROCEDURE: Endoscopic Mucosal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms|Prostate Cancer|Lung Cancer|Breast Cancer|Colon Cancer
Interventions: BIOLOGICAL: ETBX-051; adenoviral brachyury vaccine|BIOLOGICAL: ETBX-061; adenoviral Mucin-1 (MUC1) vaccine|BIOLOGICAL: ETBX-011; adenoviral Carcinoembryonic antigen (CEA) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Europe (PHY2104)
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Astigmatism
Interventions: DEVICE: IOL implantation experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Daily Condensed Tannin Supplementation and Iron Bioavailability: The Tannin Dose Response Trial
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: 95% condensed proanthocyanidins from grape seed extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: bleomycin|DEVICE: Ommaya reservoir|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Brain Injury Neurorehabilitation Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury|CVA (Cerebrovascular Accident)
Interventions: BEHAVIORAL: Cognitive Intervention with the Categorization Program|BEHAVIORAL: Social Cognitive Communication Program|DEVICE: Non-Invasive Brain Stimulation with tDCS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Amyloïd Load in Elderly Population: Effect of Cognitive Reserve
Status: UNKNOWN
Conditions: Plaque, Amyloid|Cognitive Deficits
Interventions: OTHER: PET|OTHER: MRI|OTHER: neuropsychological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Resuscitation (Voluven)|DRUG: Resuscitation (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Taxotere,CDDP and 5-FU(TPF) in Pre-treated Pts With Metastatic Esophageal Cancer.
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Taxotere|DRUG: 5-Fluorouracil|DRUG: Briplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever
Status: COMPLETED
Conditions: Relapsing Fever, Tick-Borne|Jarisch Herxheimer Reaction
Interventions: DRUG: doxycycline treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Belinostat and Carboplatin in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Carboplatin or Cisplatin
Status: COMPLETED
Conditions: Brenner Tumor|Fallopian Tube Cancer|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mixed Epithelial Carcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Ovarian Undifferentiated Adenocarcinoma|Primary Peritoneal Cavity Cancer|Recurrent Ovarian Epithelial Cancer
Interventions: DRUG: belinostat|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Device Risk Management of Atrial Fibrillation and Heart Failure
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Failure
Interventions: DEVICE: Reveal XT® Insertable Cardiac Monitor|OTHER: Heart Failure Risk Status Diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Superficial MFU-V and Diluted Calcium Hydroxyapatite for the Improvement of Lower Face Skin Quality and Wrinkles
Status: UNKNOWN
Conditions: Aging
Interventions: DEVICE: Ulthera System [Ulthera, Inc.]|DEVICE: Merz Radiesse Injectable Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Maintenance Extension of Phase I Pilot Study of Chimeric Anti-CD4 Antibody M-T412 in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: monoclonal antibody M-T412
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Sound-bed Music Therapy in Healthy Caregivers of a Hospital Oncology Ward (MTO_03)
Status: COMPLETED
Conditions: Healthy Adults (Hospital Oncology Ward)|Physiological Phenomena (e.g.HRV Parameters)|Morphology
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: sodium hyaluronate|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of AZD9567.
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD9567 10 mg|DRUG: AZD9567 20 mg|DRUG: AZD9567 40 mg|DRUG: AZD9567 80 mg|DRUG: Prednisolone 20 mg|DRUG: AZD9567 125 mg|DRUG: AZD9567 155 mg|DRUG: Prednisolone 5 mg|DRUG: Prednisolone 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Education With Hybrid Simulation Method in Patients Administering Subcutaneous Biological Drugs
Status: COMPLETED
Conditions: Self Administration|Biological Therapy|Training
Interventions: DEVICE: Training with hybrid simulation method|OTHER: Broshure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: Active tPBM-2.0|DEVICE: Sham tPBM-2.0|DRUG: 18F-MK-6240
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Movement Intervention for Memory Enhancement
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Cognitive Decline|Cognitive Impairment|Dementia, Alzheimer Type
Interventions: BEHAVIORAL: Social Dancing|BEHAVIORAL: Treadmill Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Examining the Efficacy of "Parental Vigilant Care" for Reducing Problematic Internet Usage
Status: COMPLETED
Conditions: Addiction Psychological
Interventions: BEHAVIORAL: Parental Vigilant Care (Parental training)|BEHAVIORAL: Technological Parental Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ATP150/ATP152, VSV-GP154 and Ezabenlimab in Patients With KRAS G12D/G12V Mutated PDAC (KISIMA-02)
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: VSV-GP154|DRUG: ATP150|DRUG: ATP152|DRUG: Ezabenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2)
Status: SUSPENDED
Conditions: Urinary Retention|Rectal Cancer|Urinary Catheterization
Interventions: PROCEDURE: ICCAUT|PROCEDURE: Free drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trauma Survivors Outcomes and Support Study IV
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression|Suicide|Traumatic Brain Injury|Alcohol Use|Drug Use
Interventions: BEHAVIORAL: Stepped Care Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis
Status: RECRUITING
Conditions: Maxillary Sinusitis|Sinusitis, Acute|Sinusitis
Interventions: PROCEDURE: Endoscopic sinus surgery (ESS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of NY-ESO-1 With GLA-SE in Patients With Unresectable or Metastatic Cancer
Status: COMPLETED
Conditions: Melanoma|Ovarian Cancer|Sarcoma|Non-small Cell Lung Cancer|Breast Cancer
Interventions: BIOLOGICAL: IDC-G305
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Human Cord Blood Mononuclear Cell for Delayed Encephalopathy After Carbon Monoxide Poisoning
Status: UNKNOWN
Conditions: Delayed Encephalopathy After Carbon Monoxide Poisoning
Interventions: BIOLOGICAL: Human cord blood mononuclear cell|OTHER: hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Common Bile Duct Stone Clearance Using Saline Irrigation After Stone Removal: A Prospective Randomized Control Trial.
Status: COMPLETED
Conditions: Common Bile Duct Calculi
Interventions: PROCEDURE: Saline irrigation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Loxapine in the Management of Restlessness During Mechanical Ventilation Weaning
Status: COMPLETED
Conditions: Restlessness
Interventions: DRUG: loxapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
Status: COMPLETED
Conditions: Spinocerebellar Degeneration
Interventions: DRUG: KPS-0373|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AK112 in Combination With Chemotherapy in Advanced Squamous Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Squamous Non Small Cell Lung Cancer
Interventions: DRUG: AK112, Carboplatin, Paxlitaxel|DRUG: Tislelizumab, Carboplatin, Paxlitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Clinical Trial of Oral Minoxidil 1 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Minoxidil Tablets|DRUG: Minoxidil topical solution 20 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ultrasound Guidance for Interscalene Brachial Plexus Block
Status: COMPLETED
Conditions: Shoulder|Orthopedic Surgery|Nerve Block
Interventions: PROCEDURE: Ultrasound-guided continuous interscalene brachial plexus block|PROCEDURE: Continuous interscalene brachial plexus block using electrical nerve stimulation|DRUG: Ropivacaine|DRUG: Paracetamol|DRUG: Morphine|DRUG: Fentanyl|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor With Motion Conditions
Status: COMPLETED
Conditions: Healthy|Hypoxia
Interventions: DEVICE: STRYKER SUSTAINABILITY SOLUTIONS PULSE OXIMETERS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: DRUG: Palifermin|DRUG: Panobinostat|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|DRUG: Rituximab|DRUG: Dexamethasone|DRUG: Caphosol|DRUG: Glutamine|OTHER: Oral Cryotherapy (ice chips)|DRUG: Pyridoxine|BIOLOGICAL: Stem Cell Infusion|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing an Opioid Taper Intervention Before Total Joint Arthroplasty
Status: RECRUITING
Conditions: Arthritis Knee|Arthritis Hip|Chronic Pain
Interventions: BEHAVIORAL: opioid taper
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of IV Acetaminophen and IV Ibuprofen in Reducing Post Procedural Pain in the UFE Procedure
Status: COMPLETED
Conditions: Symptomatic Uterine Fibroids and Adenomyosis
Interventions: DRUG: IV Ibuprofen|DRUG: IV Acetaminophen|DRUG: Intravenous placebo/Intravenous placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fat Absorption and Metabolism After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Bariatric Surgery
Interventions: OTHER: Metabolic test|OTHER: DXA-scan|OTHER: MRS|OTHER: Feces collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of TJ003234 (Anti-GM-CSF Monoclonal Antibody) in Subjects With Severe Coronavirus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: Coronavirus Disease 2019 COVID-19
Interventions: DRUG: TJ003234|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Psychological First Aid Intervention on Stress and Resilience in Volunteers Working in Kahramanmaraş Centered Earthquakes
Status: COMPLETED
Conditions: Psychological Resilience|Stress|Earthquake
Interventions: BEHAVIORAL: psychological first aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First in Human Study of IBI308 in Chinese Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Cancer, Solid Tumor
Interventions: DRUG: IBI308|DRUG: IBI308\Cisplatinum\Pemetrexed|DRUG: IBI308\cisplatin\gemcitabine|DRUG: IBI308\oxaliplatin\capecitabine|DRUG: IBI308\etoposide\cisplatin|DRUG: IBI308\irinotecan\5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor
Status: RECRUITING
Conditions: Labor Long
Interventions: DRUG: Oxytocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug Effects on Interpersonal Interaction
Status: COMPLETED
Conditions: Interaction, Social
Interventions: DRUG: MDMA|DRUG: placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Effects of Nemolizumab on Cytochrome P450 Substrates in Participants With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Nemolizumab|DRUG: CYP 450 Substrates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elranatamab|DRUG: Lenalidomide|DRUG: Lenalidomide|DRUG: Elranatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Axitinib for Reducing Extent of Venous Tumour Thrombus in Renal Cancer With Venous Invasion
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Non-metastatic Renal Cell Carcinoma
Interventions: DRUG: Axitinib Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Acupressure Decrease Post-operative Nausea and Vomiting (PONV) After the Pectus Excavatum Correction (NUSS) Procedure?
Status: TERMINATED
Conditions: Pectus Excavatum
Interventions: DEVICE: Acupressure (BioBand)|DEVICE: Acupressure (BioBand)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Endoscopic Sinus Surgery for Chronic Sinusitis on Asthma Control
Status: TERMINATED
Conditions: Asthma|Chronic Sinusitis
Interventions: PROCEDURE: Endoscopic Sinus Surgery|OTHER: medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Prevention Trial With Quercetin and Genistein
Status: UNKNOWN
Conditions: Primary Prevention of Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Quercetin supplement|DIETARY_SUPPLEMENT: Genistein supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: 18F-PSMA PET/MRI for the Diagnosis of Clinically Significant Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 18F-PSMA-1007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Thrombolysis With rhTNK-tPA for Acute Non-large Vessel Occlusion in Extended Time Window
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: rhTNK-tPA|DRUG: Antiplatelet Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine the Long-term Durability of Virologic Suppression in Kaletra Recipients With Imperfect Adherence
Status: COMPLETED
Conditions: HIV Infection
Interventions: OTHER: MEMS cap monitoring|OTHER: MEMS cap monitoring|OTHER: MEMS cap monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: HuMax-IL8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Behavioral Intervention for HIV Positive Prisoners in NC and TX
Status: COMPLETED
Conditions: HIV Infection
Interventions: BEHAVIORAL: Text reminders, counseling, and link coordination|BEHAVIORAL: Standard of care - control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Test Efficacy With Bioresorbable Polymer Coating Versus Bioresorbable Polymer Backbone (ISAR-RESORB)
Status: UNKNOWN
Conditions: Coronary Stenosis
Interventions: DEVICE: SYNERGY EES|DEVICE: ABSORB [BVS]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Naldebain|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Lactobacillus GG on Atopic March
Status: UNKNOWN
Conditions: Cow's Milk Allergy|Atopic Disease
Interventions: DIETARY_SUPPLEMENT: Extensively hydrolyzed casein formula + LGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|NSCLC|Adenocarcinoma|Heregulin
Interventions: DRUG: MM-121|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar Vestibulitis
Status: COMPLETED
Conditions: Interstitial Cystitis|Vulvar Diseases
Interventions: DRUG: capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation Versus Botulinum Injection on Spasticity on Children With Diplegic Cerebral Palsy
Status: ENROLLING_BY_INVITATION
Conditions: Spastic Diplegic Cerebral Palsy
Interventions: DRUG: botulinum toxin A|DEVICE: Transcranial Magnetic Stimulation|OTHER: Rehabilitation Training Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-1 and Cisplatin Before Surgery in Treating Patients With Stage IV Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: cisplatin|DRUG: tegafur-gimeracil-oteracil potassium|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diaphragm Manual Therapy With Conventional Physical Therapy in Chronic Non-Specific Low Back Pain Patients
Status: COMPLETED
Conditions: Low Back Pain|Chronic Low-back Pain
Interventions: OTHER: Manual Diaphragm Technique|OTHER: Conventional Physical Therapy|OTHER: Sham Diaphragm Manual Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Plus Cetuximab for Incurable Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Pazopanib|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of BI 1026706 in Healthy Chinese and Japanese Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1026706|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine Effect on Perivascular Inflammation Index on Coronary CTA
Status: RECRUITING
Conditions: Atherosclerosis|Inflammatory Response|Coronary Disease
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Roles of Estrogen and Progesterone in Heart Metabolism
Status: TERMINATED
Conditions: Postmenopausal Syndrome
Interventions: DRUG: Estrogen|DRUG: Progesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatine Based Adjuvant Chemotherapy for Stage II/III Colorectal Cancer: 8 Cycles Versus 12 Cycles
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: 12 cycles of oxaliplatine based adjuvant chemotherapy|DRUG: 8 cycles of oxaliplatine based adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elective Mucosal Irradiation in Head-and-Neck Cancer of Unknown Primary
Status: UNKNOWN
Conditions: Head-and-neck Cancer|Carcinoma of Unknown Primary
Interventions: RADIATION: Elective mucosal irradiaton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload
Status: COMPLETED
Conditions: Iron Overload Due to Repeated Red Blood Cell Transfusions
Interventions: DRUG: Deferiprone DR tablets 1000 mg (Low dosage)|DRUG: Deferiprone DR tablets 1000 mg (High dosage)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Various Respiratory Syncytial Virus (RSV) Pre-Fusion (preF)-Based Vaccine Formulations in Adults Aged 60 Years and Older
Status: TERMINATED
Conditions: Respiratory Syncytial Virus-associated Lower Respiratory Tract Disease Prevention
Interventions: BIOLOGICAL: RSV preF-based Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Oxytocin for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcohol Misuse
Interventions: DRUG: Instranasal Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Glyburide|DRUG: Metformin|DRUG: Glyburide-Metformin combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus, Lupus Nephritis
Interventions: DRUG: Oral prednisolone|DRUG: Rituximab|DRUG: Mycophenolate mofetil|DRUG: Methyl prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Trial: Study of the Renata Minima Stent
Status: ACTIVE_NOT_RECRUITING
Conditions: Coarctation of the Aorta|Pulmonary Artery Stenosis
Interventions: DEVICE: Catheterized Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combivent® CFC Metered Dose Inhaler (MDI) in Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Combivent® CFC MDI|DRUG: Albuterol HFA MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of GSK1349572 Versus Raltegravir (RAL) With Investigator Selected Background Regimen in Antiretroviral-Experienced, Integrase Inhibitor-Naive Adults
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: GSK1349572|DRUG: Raltegravir|DRUG: GSK1349572 Placebo|DRUG: Raltegravir Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief
Status: COMPLETED
Conditions: Obstetric Pain
Interventions: DRUG: Wound infiltration by Bupivacaine|DRUG: Wound infiltration by Pethidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) in Adult Patients With Rheumatoid Arthritis (SVOBODA Programme)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Clinical Study to Assess the Clinical Safety of a New Compression Device in Subjects With Peripheral Arterial Vascular Disease
Status: COMPLETED
Conditions: Peripheral Arterial Vascular Disease
Interventions: PROCEDURE: A new treatment approach is to have an effective working pressure combined with a low resting pressure.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT Versus Hypofractionated Radiotherapy for Biochemically Recurrent or Oligometastatic Prostate Adenocarcinoma
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Oligometastatic Prostate Carcinoma|Recurrent Prostate Adenocarcinoma|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: DRUG: Antiandrogen Therapy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|RADIATION: Hypofractionated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Stereotactic Body Radiation Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies of Left Ventricular Dysfunction (SOLVD)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Heart Failure|Hypertension|Myocardial Ischemia
Interventions: DRUG: enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: COMPARATIVE STUDY OF BONE IMPLANT CONTACT (BIC) ON NEW BONE REGENERATED WITH AUTOGENOUS DENTIN AND NATIVE BONE
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Resorption|Bone Regeneration
Interventions: PROCEDURE: socket preservation|PROCEDURE: placement of experimental implants|PROCEDURE: histological sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)
Status: RECRUITING
Conditions: Refractory IPA
Interventions: DRUG: PC945|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Prevention Clinic for Men With Risk of Familial Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Familial Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Panel sequencing, whole exome sequencing, whole genome sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD Therapy
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: liraglutide|DRUG: exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia
Status: UNKNOWN
Conditions: Dyslipidemia
Interventions: DRUG: High-dose rosuvastatin|DRUG: Statin plus fenofibrate|DRUG: Statin plus niacin ER/laropiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: dl-alpha-tocopherol|DRUG: Memantine|DRUG: dl-alpha-tocopherol|DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Cogane™ in Healthy Volunteers and Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Cogane™ (PYM50028)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Combined With Endostar and Envafolimab in Elderly Patients With Locally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Endostar and Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Carbon Dioxide Drug Delivery System (CDDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thalidomide and Chemoembolization With Doxorubicin in Treating Patients With Liver Cancer That Cannot be Removed by Surgery
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer
Interventions: DRUG: thalidomide|DRUG: doxorubicin hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of Chiglitazar for NASH
Status: COMPLETED
Conditions: NASH
Interventions: DRUG: chiglitazar sodium tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nociceptors, Neurotrophic Factors and Cytokine Expression in Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastro-esophageal Reflux Disease
Interventions: PROCEDURE: endoscopic mucosal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BIO|MASTER.Ilivia Family / Plexa
Status: COMPLETED
Conditions: Heart Failure|Tachyarrhythmia
Interventions: DEVICE: Ilivia ICD Family|DEVICE: Plexa ICD lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Functional Rehabilitation With HUBER Platform in the Treatment of Non-specific Chronic Low Back Pain.
Status: UNKNOWN
Conditions: Chronic Low-back Pain
Interventions: BEHAVIORAL: HUBER exercises|BEHAVIORAL: Standard exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of Single-use Precision Filtered Infusion Sets for Intravenous Infusion
Status: COMPLETED
Conditions: Single-use Precision Filter Infusion Set
Interventions: DEVICE: single-use precision filtered infusion sets|DEVICE: single-use precision filter infusion set with needle
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity of SA 14-14-2 JE Vaccine
Status: COMPLETED
Conditions: Healthy Infants
Interventions: BIOLOGICAL: JE Vaccine existing facility|BIOLOGICAL: JE vaccine new plant lot 1|BIOLOGICAL: JE vaccine new plant lot 2|BIOLOGICAL: JE vaccine new plant lot 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Once Monthly Subcutaneous Mircera in Patients With Chronic Renal Anemia Not on Dialysis
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lateral Kangaroo Care in Hemodynamic Stabilization of Premature Infant.
Status: UNKNOWN
Conditions: Kangaroo Care|Premature Infant|Body Temperature
Interventions: PROCEDURE: Lateral|PROCEDURE: Prone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Tendoactive, Eccentric Training, and the Combination of Both as a Treatment of Achilles Tendinopathy
Status: COMPLETED
Conditions: Achilles Tendinopathy
Interventions: DRUG: Tendoactive|BEHAVIORAL: Eccentric training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome
Status: TERMINATED
Conditions: Von Hippel-Lindau Syndrome
Interventions: DRUG: Sunitinib Malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Tea Catechins and Caffeine in Relation to Energy Metabolism
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: green tea|DIETARY_SUPPLEMENT: Mix of catechins and caffeine|DIETARY_SUPPLEMENT: EGCG|DIETARY_SUPPLEMENT: EGC|DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Status: RECRUITING
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: Plozasiran Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|B Acute Lymphoblastic Leukemia|Lymphocytic Neoplasm|Lymphoma
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Bendamustine|BIOLOGICAL: Filgrastim-sndz|DRUG: Fludarabine|BIOLOGICAL: Inotuzumab Ozogamicin|DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation|BIOLOGICAL: Rituximab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma|Non Small Cell Lung Carcinoma|Irinotecan Sensitive Cancers
Interventions: DRUG: Carfilzomib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disruption of Immune Homeostasis in Type 2 Diabetics With Generalized Chronic Periodontitis
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Type 2 Diabetes Mellitus|Periodontal Diseases|Periodontitis|Chronic Periodontitis
Interventions: PROCEDURE: Nonsurgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)
Status: RECRUITING
Conditions: Head and Neck Cancer Survivors|Cancer of the Head and Neck Surviors
Interventions: OTHER: Ototoxicity Screening Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients
Status: COMPLETED
Conditions: Caregiver|Malignant Neoplasm|Physician|Stage I Colorectal Cancer AJCC v8|Stage I Liver Cancer|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Colorectal Cancer AJCC v8|Stage II Liver Cancer|Stage II Lung Cancer AJCC v8|Stage IIA Colorectal Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Colorectal Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage IIC Colorectal Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Liver Cancer|Stage III Lung Cancer AJCC v8|Stage IIIA Colorectal Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Colorectal Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Colorectal Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: BEHAVIORAL: Patient Navigation Program|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Costal Cartilage Donor-site Pain: Does Abdominal Muscle Infiltration Analgesia Work?
Status: COMPLETED
Conditions: Rectus Abdominis and External Oblique Muscle Infiltration Analgesia
Interventions: PROCEDURE: rectus abdominis(RAM) and external oblique muscle(EOM) infiltration analgesia|PROCEDURE: intravenous patient-controlled anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Imaging Exam of Convalesced COVID-19 Patients
Status: ENROLLING_BY_INVITATION
Conditions: COVID-19|COVID Long-Haul
Interventions: OTHER: Magnetic Resonance Imaging|OTHER: Ultra-High Resolution Computed Tomography (CT) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER