pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility Study of a Mobile Health App for Symptom Monitoring in People With Chronic Pancreatitis
Status: NOT_YET_RECRUITING
Conditions: Chronic Pancreatitis
Interventions: DEVICE: SmartCP (mobile phone app)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Veterans Walk for Health Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes Mellitus|Hyperlipidemia|Hypertension|Obesity
Interventions: BEHAVIORAL: Nutritional counseling|BEHAVIORAL: Walking program|BEHAVIORAL: Nutritional counseling|BEHAVIORAL: Walking program|DEVICE: Simple pedometer|BEHAVIORAL: Nutritional counseling|BEHAVIORAL: Walking program|DEVICE: Simple pedometer|DEVICE: Enhanced pedometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Psychometric Validation of the Competitive Attention Test
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: experience 1 : Competitive attention test in healthy participants|OTHER: experience 2 : Competitive attention test in patients with ADHD with no treatment|OTHER: experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study on Treatment of Postmenopausal Osteoporosis (Kidney Deficiency and Blood Stasis Syndrome) With Xulin Jiangu Granules
Status: UNKNOWN
Conditions: Postmenopausal Osteoporoses
Interventions: DRUG: Xulin Jiangu granules|DRUG: Calcitriol capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring Biomarkers of the Carcinogenesis of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas
Status: RECRUITING
Conditions: Intraductal Papillary Mucinous Neoplasm
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Diagnostic Yield and Safety of Transbronchial Cryobiopsy in Different Freezing Time in the Diffuse Parenchymal Lung Diseases
Status: UNKNOWN
Conditions: Transbronchial Cryobiopsy|Freezing Time|Diagnostic Yield|Safety
Interventions: PROCEDURE: Transbronchial Cryobiopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Number of Pulses of Radial Extracorporeal Shock Wave Therapy on Hamstring Spasticity in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Spasticity, Muscle|Cerebral Palsy|Child; Spastic
Interventions: DEVICE: radial Extracorporeal Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Types of Fixation of Vancouver B1 Periprosthetic Fractures
Status: UNKNOWN
Conditions: Femur Fractures
Interventions: PROCEDURE: Isolated Locked Compression Plate|PROCEDURE: Cable Plating and Strut Allograft with Cerclage Wiring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Effectiveness Trial of Early Hemodynamic Support in Patients Demonstrating a Low Systolic Blood Pressure
Status: WITHDRAWN
Conditions: Intraoperative Low Blood Pressure
Interventions: OTHER: low blood pressure alert|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament
Status: COMPLETED
Conditions: Sprains and Strains|Pain
Interventions: DRUG: tramadol HCl + acetaminophen; hydrocodone bitartrate + acetaminophen; placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety and Efficacy of Lubricin Eye Drops vs Sodium Hyaluronate Eye Drops in Subjects With Mod. Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome|Tear Film Insufficiency
Interventions: DEVICE: Lubricin|DEVICE: Sodium Hyaluronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Cerebral Glucose Metabolism After Electroconvulsive Therapy (ECT)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Electroconvulsive therapy|DEVICE: 18-Fluoro-desoxy-glucose positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation
Status: COMPLETED
Conditions: Hyperpigmentation|Post-inflammatory Hyperpigmentation|Acne
Interventions: OTHER: Topical Cetyl Tranexamate Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivestim® (Filgrastim) Tolerance in Patients Treated by Toxic Chemotherapeutic Agents
Status: COMPLETED
Conditions: Solid Tumors|Malignant Hemopathy|Chemotherapy-induced Febrile Neutropenia (FN)
Interventions: BIOLOGICAL: Nivestim®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of MR-guided Focused Ultrasound (MRgFUS) Bilateral Capsulotomy for the Treatment of Refractory Obsessive-compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DEVICE: Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effects of Two Types of t-DCS Stimulation on Robot-assisted Gait Training in Patients With Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis|Transcranial Direct Current Stimulation
Interventions: COMBINATION_PRODUCT: Transcutaneous Spinal Direct Current Stimulation and Transcranial Direct Current Stimulation|COMBINATION_PRODUCT: Sham ts-DCS and sham t-DCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Open-label, Prospective Evaluation of the Ulthera® System for Lifting Submental (Under the Chin) and Neck Tissue in Chinese Patients
Status: COMPLETED
Conditions: Mild to Moderate Skin Laxity Under the Chin|Mild to Moderate Skin Laxity on Neck
Interventions: DEVICE: Microfocused ultrasound with visualization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gaze Contingent Feedback in Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depression, Unipolar|Depressive Disorder|Depressive Disorder, Major
Interventions: BEHAVIORAL: Attention Modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Melanoma
Interventions: DRUG: temozolomide|OTHER: flow cytometry|OTHER: staining method|PROCEDURE: biopsy|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: SMT19969|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Patient Education With Virtual Reality
Status: NOT_YET_RECRUITING
Conditions: Anxiety|Cancer
Interventions: BEHAVIORAL: Two Dimensional (2D) Informational Video|BEHAVIORAL: First-Person Virtual Reality Video|BEHAVIORAL: Third-Person Virtual Reality Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TG-1801 Alone or in Combination With Ublituximab in Subjects With B-Cell Lymphoma or Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: CLL|SLL|Richter's Transformation|Indolent Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Aggressive Lymphoma|DLBCL|Mediastinal Large B-cell Lymphoma|MCL
Interventions: BIOLOGICAL: TG-1801|BIOLOGICAL: Ublituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oncological Physiotherapy on Painful Shoulder Cervical Ganglion in Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Shoulder Pain|Rehabilitation
Interventions: OTHER: Therapeutic upper limb strength exercise treatment|OTHER: Treatment with passive and active mobilization of the upper limb.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Replacement of Saturated Fat in Dairy on Total Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: MUFA-rich dairy products (UHT milk, cheese and butter)|DIETARY_SUPPLEMENT: Conventional dairy products (UHT milk, cheese, butter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Local Skin Incision Infiltration by Oxytocin On Wound Healing
Status: RECRUITING
Conditions: Wound Heal|Scar; Previous Cesarean Section
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects
Status: COMPLETED
Conditions: Emotions|Mood|Cognitive Function 1, Social|Empathy
Interventions: DRUG: DMT|DRUG: Harmine|DRUG: Placebo (Harmine)|DRUG: Placebo (DMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: CsA eye gel|DRUG: CsA for eye emulsion|DRUG: Hypromellose Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound and Biomarker Tests in Predicting Cancer Aggressiveness in Tissue Samples of Patients With Bladder Cancer
Status: TERMINATED
Conditions: Bladder Papillary Urothelial Carcinoma|Stage 0a Bladder Urothelial Carcinoma|Stage 0is Bladder Urothelial Carcinoma|Stage I Bladder Cancer With Carcinoma In Situ|Stage I Bladder Urothelial Carcinoma|Stage II Bladder Urothelial Carcinoma|Stage III Bladder Urothelial Carcinoma|Stage IV Bladder Urothelial Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Use of the Neotech RAM Nasal Cannula for CPAP and Bi-PAP Application in Infants 28-42 Weeks Gestation in a Neonatal Intensive Care Unit (NICU)
Status: TERMINATED
Conditions: Neonatal Respiratory Distress
Interventions: OTHER: RAM Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease
Status: COMPLETED
Conditions: Primary IgA Nephropathy
Interventions: DRUG: NEFECON|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for G1b CHC Patients With CKD-3 Treated With Grazoprevir Plus Elbasvir
Status: COMPLETED
Conditions: Hepatitis C Viral|Chronic Kidney Disease stage3
Interventions: DRUG: Grazoprevir plus Elbasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and Pharmacokinetics of Single Rising Doses of BEA 2180 BR in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR - rising dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1
Interventions: DRUG: N-acetylcysteine (NAC)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LoVE4MUM: Virtual Engagement for Preventing Postpartum Depression
Status: NOT_YET_RECRUITING
Conditions: Postpartum Depression|Maternal Behavior|mHealth Intervention|Mental Health Issue
Interventions: DEVICE: LoVE4MUM mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Lubiprostone|DRUG: Lubiprostone|DRUG: Lubiprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Furosemide-Q12 hour bolus|DRUG: Furosemide-Continuous Infusion|DRUG: Furosemide-Low Intensification|DRUG: Furosemide-High Intensification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bio-equivalence Study of Sofosbuvir From Magicbuvir 400 mg Film Coated Tablets ( Magic Pharma, Egypt) Versus Sovaldi 400 mg Tablets (Gilead Sciences, Canada)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Magicbuvir|DRUG: Sovaldi (fist dose)|DRUG: Sovaldi (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Nesvategrast (OTT166) in Diabetic Retinopathy (DR)
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: OTT166|DRUG: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib for Advanced Soft Tissue Sarcoma Patients: a Phase 2, Multicenter Trial
Status: WITHDRAWN
Conditions: Soft Tissue Sarcoma Adult|Advanced Cancer
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: CJ-12420 100 mg QD|DRUG: Esomeprazole 40 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Phase III Trial of Sorafenib With or Without cTACE in Patients With Advanced HCC
Status: COMPLETED
Conditions: Advanced Adult Hepatocellular Carcinoma
Interventions: OTHER: Conventional Transarterial Chemoembolization (cTACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Support on End-of-life Care Planning in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: COPD Patient Decision Aid|OTHER: General Health Coaching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Vascular Calcification|Renal Insufficiency|End Stage Renal Failure on Dialysis
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The PRIME Study: A Randomized, Controlled, Prospective Study
Status: RECRUITING
Conditions: Patient Preference|Patient Outcomes|Post-Operative Inflammation|Grade of Post-Operative Cystoid Macular Edema|Rate of Post-Operative Cystoid Macular Edema
Interventions: DRUG: Dextenza|DRUG: Topical Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam|DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Concomitant Montelukast Sodium and Levocetirizine Dihydrochloride in Perennial Allergic Rhinitis (PAR) Patients
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Montelukast + Levocetirizine|DRUG: Levocetirizine|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Magnetic Resonance Imaging and Spectroscopy Software in the Improvement of Image Quality
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Magnetic Resonance Spectroscopic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety Study of S-Caine Peel (Skin Numbing Cream) Before a Painful Dermatologic Procedure in Adults
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education With Cartoon's Effectiveness on Disease Management of the Children With Asthma
Status: COMPLETED
Conditions: Asthma in Children
Interventions: OTHER: Standart Care given during normal examination|BEHAVIORAL: Health Promotion Program with cartoon education for Children with Asthma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-Market Clinical Evaluation of the Zephyr Valve 5.5-LP EBV
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: DEVICE: The Pulmonx Zephyr Endobronchial Valve (EBV) 5.5- LP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Post-Acute COVID-19 Syndrome in Improvement of COVID-19 Rehabilitated Patients by Respiratory Training
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19, Post-Acute COVID-19 Syndrome, Dyspnea, Incentive Spirometer
Interventions: DEVICE: breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Anticoagulant Discontinuation, Adherence Patterns, Hospitalizations and Costs in Non-Valvular Atrial Fibrillation (NVAF) Patients
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: apixaban|DRUG: dabigatran|DRUG: rivaroxaban|DRUG: warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer
Status: RECRUITING
Conditions: Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|Infiltrating Cervical Carcinoma|Metastatic Cervical Carcinoma|Recurrent Cervical Carcinoma|Stage I Cervical Cancer FIGO 2018|Stage IA Cervical Cancer FIGO 2018|Stage IA1 Cervical Cancer FIGO 2018|Stage IA2 Cervical Cancer FIGO 2018|Stage IB Cervical Cancer FIGO 2018|Stage IB1 Cervical Cancer AJCC v8|Stage IB2 Cervical Cancer FIGO 2018|Stage IB3 Cervical Cancer FIGO 2018|Stage II Cervical Cancer FIGO 2018|Stage IIA Cervical Cancer FIGO 2018|Stage IIA1 Cervical Cancer FIGO 2018|Stage IIA2 Cervical Cancer FIGO 2018|Stage IIB Cervical Cancer FIGO 2018|Stage III Cervical Cancer FIGO 2018|Stage IIIA Cervical Cancer FIGO 2018|Stage IIIB Cervical Cancer FIGO 2018|Stage IIIC Cervical Cancer FIGO 2018|Stage IIIC1 Cervical Cancer FIGO 2018|Stage IIIC2 Cervical Cancer FIGO 2018|Stage IV Cervical Cancer FIGO 2018|Stage IVA Cervical Cancer FIGO 2018|Stage IVB Cervical Cancer FIGO 2018
Interventions: PROCEDURE: Biospecimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Antipsychotic Adherence Among Patients With Serious Mental Illness
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: BEHAVIORAL: Unit of use medication packaging|BEHAVIORAL: Mailed reminders to patient when medication refills are due|BEHAVIORAL: Note to Mental Health Provider when refill is overdue|PROCEDURE: Aligning all prescriptions to fall due on same date
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness and Safety of Irinotecan Liposome Injection, 5-fluorouracil/Leucovorin Plus Oxaliplatin in Patients Not Previously Treated for Metastatic Pancreatic Cancer, Compared to Nab-paclitaxel+Gemcitabine Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Adenocarcinoma of the Pancreas
Interventions: DRUG: Irinotecan Liposomal Injection|DRUG: Oxaliplatin|DRUG: 5Fluorouracil|DRUG: Leucovorin|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection Management With Betaferon: Influence on Adherence, Patients Satisfaction and Health Related Outcomes (BETAPATH)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (Betaseron, BAY86-5046)|DRUG: Interferon beta-1b (Betaseron, BAY86-5046)|DRUG: Interferon beta-1b (Betaseron, BAY86-5046)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: DRUG: NSAIDs; adjunctive analgesics; adjunctive anti-depressants|PROCEDURE: Lumbar epidural injection|OTHER: Joint Mobilizations (spine, sacroiliac, hip)|OTHER: Individualized exercises: clinical setting|OTHER: Group Exercise: community setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and Safety of 48-week Treatment With Clevudine 30mg Versus Lamivudine 100mg for CHB Infection
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Clevudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hi-maize Resistant Starch on Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: OTHER: Hi-maize starch (Low dose)|OTHER: Hi-maize starch (High-dose)|OTHER: Control (starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Changes in Pancreatic Fat Content Using Advanced MR Sequences in Diabetics on Dapagliflozin Therapy
Status: COMPLETED
Conditions: Pancreatic Lipomatosis
Interventions: DRUG: Dapagliflozin 10mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: EC Followed Docetaxel Versus ET Followed Capecitabine as Adjuvant Chemotherapy for Node Positive Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE® CARDIOFORM Septal Occluder Migraine Clinical Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine|Patent Foramen Ovale|PFO - Patent Foramen Ovale
Interventions: DEVICE: Actual device PFO closure|DRUG: Thienopyridine (clopidogrel or prasugrel)|DEVICE: Sham device PFO closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 Variant
Status: COMPLETED
Conditions: Hypertension Essential|Salt Excess|Genetic Hypertension
Interventions: DRUG: Amiloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Predictive Factors for Anastomotic Leakage After Colorectal Surgery
Status: COMPLETED
Conditions: Anastomotic Leakage|Colorectal Cancer|Anastomotic Leak|Colorectal Neoplasms|Colorectal Carcinoma|Colorectal Tumors
Interventions: OTHER: No interventions, only data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia
Status: COMPLETED
Conditions: Postbariatric Hypoglycemia
Interventions: DRUG: exendin 9-39|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of ELAPR002f Injectable Gel for the Improvement of Skin Quality in Adult Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Quality Deficit
Interventions: DEVICE: ELAPR002f Injectable Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canadian Manufactured Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine Compared With U.S. Manufactured Td
Status: COMPLETED
Conditions: Diphtheria|Tetanus
Interventions: BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine|BIOLOGICAL: Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACTIV-5 / Big Effect Trial (BET-C) for the Treatment of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Danicopan|OTHER: Placebo|DRUG: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Added Value of a Small Camera (Iriscope) in the Endoscopic Diagnosis of Peripheral Lung Nodules and Masses
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary
Interventions: DEVICE: Iriscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Status: COMPLETED
Conditions: Hyperemesis Gravidarum
Interventions: OTHER: Pregnancy Unique Questionnaire of Emesis (PUQE)|OTHER: 24 hours self-reported nutritional intake form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Performance of Incremental and Bulk Fill Composites in Class II Restorations
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Supreme Universal Restorative|DEVICE: Supreme Flowable Restorative|DEVICE: Bulk Fill Flowable Restorative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy on Cognition in Neurorehabilitation
Status: COMPLETED
Conditions: Dementia|Stroke|Traumatic Brain Injury
Interventions: OTHER: Passive Music Therapy (P)|OTHER: Active Music Therapy (A)|OTHER: Standard Care Control Condition (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Substudy - Low Dose of Abatacept in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CDx Biopsies for Detection of Laryngopharyngeal Reflux and Laryngeal Lesions
Status: WITHDRAWN
Conditions: Laryngeal Disease|Laryngeal Tumor|Laryngopharyngeal Reflux
Interventions: DEVICE: Endo CDx Brush biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: EN3342
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Switching From an E/C/F/TAF Fixed-Dose Combination (FDC) Regimen or a TDF Containing Regimen to B/F/TAF FDC in Human Immunodeficiency Virus-1 (HIV-1) Infected Participants Aged ≥ 65 Years
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye
Status: TERMINATED
Conditions: Dry Eye
Interventions: DRUG: Cyclosporine A 0.05%|DRUG: Arificial Tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of CSL112 in Healthy Adults and in Adults With Moderate Renal Impairment
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BIOLOGICAL: CSL112|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colon Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Microsatellite Stable Colorectal Carcinoma|Metastatic Rectal Adenocarcinoma|Stage IV Colon Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Balstilimab|BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Botensilimab|PROCEDURE: Computed Tomography|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|PROCEDURE: Magnetic Resonance Imaging|DRUG: Oxaliplatin|PROCEDURE: Positron Emission Tomography|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PMA-Zeolite-Clinoptilolite Effects in Crohn Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DEVICE: cellulose|DEVICE: PMA-zeolite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of ART® on Lower Limb Myofascial Pain and Function
Status: COMPLETED
Conditions: Muscle Injury|Lower Limb Injury
Interventions: OTHER: Active Release Techniques®|OTHER: Sham Active Release Techniques®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Valsartan/Amlodipine Combination in Patients With Severe Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan/amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficiency of γδ T Cell Against Hepatocellular Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: BIOLOGICAL: DC-CIK cells|BIOLOGICAL: γδ T cells|BIOLOGICAL: γδ T/DC-CIK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Duration of Pre-oxygenation on Apnea Tolerance in Obese Patients During the Induction of General Anesthesia
Status: RECRUITING
Conditions: Anesthesia
Interventions: OTHER: Control|OTHER: PreOx_3min|OTHER: PreOx_6min
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia in Remission|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: busulfan|DRUG: fludarabine phosphate|DRUG: methotrexate|DRUG: tacrolimus|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT Combined With Adbelimumab and Apatinib for Perioperative and Conversion Therapy of Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|SBRT|Immune Checkpoint Blockade|Tyrosine Kinase Inhibitor
Interventions: DRUG: adbelimumab|PROCEDURE: SBRT|DRUG: apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Operant Learning Versus Energy Conservation Activity Pacing Treatments in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain
Interventions: BEHAVIORAL: Operant Learning|BEHAVIORAL: Energy Conservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy, Pharmacokinetics and Safety Between CT-P13 and China Approved Remicade When Co-administered With Methotrexate in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: CT-P13|BIOLOGICAL: Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasal Polyposis
Interventions: BIOLOGICAL: Benralizumab 30 mg|BIOLOGICAL: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean Section
Status: UNKNOWN
Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: IV Cyclizine versus IV Dexamethasone for prevention of nausea and vomiting after intrathecal morphine in patients undergoing cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Dasatinib|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyvinyl Alcohol Embolization Microspheres
Status: ENROLLING_BY_INVITATION
Conditions: Primary Liver Cancer
Interventions: DEVICE: Embosphere and chemotherapy drug|DEVICE: Polyvinyl alcohol embolization microspheres (Huihe Medical) and chemotherapy drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MEN1611 With Trastuzumab (+/- Fulvestrant) in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Advanced or Metastatic Breast Cancer
Interventions: DRUG: MEN1611|DRUG: Trastuzumab|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder \(MDD|Depressive Disorder, Major
Interventions: DEVICE: Active VeNS Device|DEVICE: Sham VeNS Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Chemoradiation Followed by VIPD in Nasal Natural Killer (NK)/T-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, T-Cell
Interventions: DRUG: Concurrent Radiotherapy (RT)/cisplatin, VIPD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction Bleeding in Laminectomy With Double Doses of Tranexamic Acid
Status: COMPLETED
Conditions: Bleeding
Interventions: DRUG: tranexamic acid|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects and Safety of Epidural PDRN vs. Placebo
Status: UNKNOWN
Conditions: Spinal Stenosis Lumbar
Interventions: DRUG: Polydeoxyribonucleotides|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Safety of 3D Printed Wrist-based Splints
Status: COMPLETED
Conditions: Distal Radius Fracture|Scaphoid Fracture
Interventions: DEVICE: Swibrace 3D-splint|DEVICE: Plaster cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Body Temperature in Persons With Tetraplegia When Exposed to Cold
Status: COMPLETED
Conditions: Tetraplegia|Hypothermia|Mild Cognitive Impairment
Interventions: DRUG: Midodrine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury
Status: COMPLETED
Conditions: Lung Injury, Acute
Interventions: DRUG: Dose 1 GSK2586881|DRUG: Dose 2 GSK2586881|DRUG: Dose 3 GSK2586881|DRUG: Dose 4 GSK2586881|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR) in High-risk Treatment-naive Patients With Follicular Lymphoma (FL)
Status: NOT_YET_RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Renal Toxicity
Interventions: DRUG: methotrexate|OTHER: medical chart review|PROCEDURE: assessment of therapy complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trastuzumab Emtansine in Treating Patients With HER2-Positive Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: HER2/Neu Positive|Recurrent Breast Carcinoma|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|BIOLOGICAL: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physiotherapy for the Treatment of Fecal Incontinence.
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: BEHAVIORAL: Individual supervised pelvic floor muscle exercises|OTHER: Massage of the neck and back|BEHAVIORAL: Standard information and guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate LB1148 for Return of Gastrointestinal Function, Decrease Post-Operative Ileus
Status: COMPLETED
Conditions: Ileus
Interventions: DRUG: LB1148|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Bowel Preparation Before Colonoscopy
Status: RECRUITING
Conditions: Bowel Preparation
Interventions: DRUG: OSS|DRUG: OSS+Linzess|DRUG: PEG-Interferon Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Disulfiram and Copper Gluconate in Patients With Treatment-Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Disulfiram|DRUG: Copper Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Stem Cell Transplant With Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|CLL|Chronic Lymphocytic Leukemia|Lymphoma|Hodgkin Lymphoma
Interventions: RADIATION: Total Body Irradiation|PROCEDURE: Haploidentical Stem Cell Transplantation|BIOLOGICAL: CD56-Enriched Donor Lymphocyte Infusion|DRUG: Bendamustine|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angel® Catheter Post Market Registry
Status: UNKNOWN
Conditions: Pulmonary Embolism|Medical Device Complication|Deep Vein Thrombosis|Catheter Thrombosis|Catheter-related Bloodstream Infection (CRBSI) Nos
Interventions: DEVICE: Angel® Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: Cocaine-Related Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigation of Safety+Efficacy of Different Doses of RagweedMATAMPL;Assessment of Residual Allergenicity Using Skin Prick Test
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: RagweedMATAMPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy and Proprioceptive Neuromuscular Facilitation in Field Hockey Players.
Status: COMPLETED
Conditions: Hockey Players Whith Lower Back and Hamstring Pain
Interventions: OTHER: Manual Therapy|OTHER: Proprioceptive neuromuscular facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT