pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Sparse Uterine Closure in Cesarean Section
Status: COMPLETED
Conditions: Caesarean Scar Defect
Interventions: PROCEDURE: sparse uterine suture|PROCEDURE: one layer uterine closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare and Assess the Safety and Pharmacokinetic Characteristics After Oral Administration of Fimasartan (BR-A-657∙K) in Healthy Elderly and Young Male Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Low-cost Microbiological Water Test Kits
Status: COMPLETED
Conditions: Diarrhea|E.Coli Infections
Interventions: OTHER: Community and household water safety education sessions|OTHER: Household-specific water quality information|OTHER: Low-cost microbiological water test kits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ALateral Flow Assay to Detect QSOX1 Peptide in Patients With or at Risk for Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreas Cancer|Pancreas Cyst
Interventions: OTHER: Lateral Flow Assay (LFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patients With Type 2 Diabetes Mellitus With Insufficient Glycaemic Control Despite Treatment With Metformin Alone or Metformin in Combination With a Sulfonylurea
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: BI 10773
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes
Status: TERMINATED
Conditions: Metabolic Syndrome
Interventions: DRUG: Ramipril|DRUG: HCTZ-hydrochlorothiazide|DRUG: Ramipril+HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine(s) GSK3277510A and GSK3277509A in Adults 18 to 60 Years of Age
Status: WITHDRAWN
Conditions: Influenza
Interventions: BIOLOGICAL: Investigational H7N9 vaccine GSK3277510A|BIOLOGICAL: Investigational H7N9 vaccine GSK3277509A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-site Study of Rapid Diagnostic Syphilis Assays
Status: COMPLETED
Conditions: Syphilis
Interventions: DEVICE: Abbott Laboratories Determine test for syphilis|DEVICE: Investigational syphilis immunochromatographic strip test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Qigong vs. Aerobic Exercise in the Treatment of Childhood Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Muscular Disease|Fibromyalgia
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Qigong exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Caudal Block and Erector Spinae Block for Postoperative Analgesia
Status: COMPLETED
Conditions: Circumcision|Lower Abdominal Surgery
Interventions: PROCEDURE: Regional anesthesia intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Changing the Healthcare Delivery Model
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: mobile health care application|BEHAVIORAL: CHWs and mobile health care application|BEHAVIORAL: Community Health Worker (CHW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Usefulness of Non-contrast MagnetIc Resonance imAging Versus Non-Contrast Ultrasonography for surveiLlancE of HepatoCellular Carcinoma [MIRACLE-HCC]
Status: UNKNOWN
Conditions: Compensated Liver Cirrhosis
Interventions: RADIATION: Ultrasonography|RADIATION: non-contrast MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Placebo|DRUG: Adjuvant endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Pharmacokinetics of Carfilzomib in Patients With Relapsed and Refractory Multiple Myeloma and Varying Degrees of Renal Function
Status: COMPLETED
Conditions: Multiple Myeloma|Renal Insufficiency
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Stem Cells in Cirrhosis Patients
Status: COMPLETED
Conditions: Stem Cell Transplantation|Cirrhosis
Interventions: BIOLOGICAL: CD133|BIOLOGICAL: BM-MNC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Retrograde Reperfusion of Renal Graft to Reduce Ischemic-reperfusion Injury
Status: UNKNOWN
Conditions: Kidney Transplantation|Ischemic Reperfusion Injury|Reperfusion
Interventions: PROCEDURE: Retrograde renal graft reperfusion|PROCEDURE: Conventional antegrade renal graft reperfusion (without retrograde reperfusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Envafolimab Plus Docetaxel In Combination With or Without Trilaciclib Versus Docetaxel in Advanced NSCLC
Status: NOT_YET_RECRUITING
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: Trilaciclib+Envafolimab+Docetaxel|DRUG: Envafolimab+Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia
Interventions: DRUG: Olverembatinib plus venetoclax and dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CABI: Antibiotic Duration for Complicated Intra-ABdominal Infection
Status: COMPLETED
Conditions: Complicated Intraabdominal Infections
Interventions: OTHER: < 10 days of antibiotics|OTHER: 28 days of antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prebiotic Food-enriched Diet (PreFED) to Enhance the Microbiome and Response to First-line Immunotherapy in Unresectable Melanoma
Status: NOT_YET_RECRUITING
Conditions: Unresectable Melanoma
Interventions: OTHER: Prebiotic Food-Enriched Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abscopal Effect of Radiotherapy and Nivolumab in Relapsed Hodgkin Lymphoma After Anti-PD1 Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: OTHER: Nivolumab plus radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IMC-A12, Alone or in Combination With Cetuximab, in Participants With Recurrent or Metastatic Squamous Cell Carcinoma (MSCC) of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: IMC-A12 (cixutumumab)|BIOLOGICAL: cetuximab (Erbitux ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bazedoxifene Acetate as a Remyelinating Agent in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Bazedoxifene Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety of Olaparib in Chinese Patients With Ovarian Cancer in the Real-World Setting
Status: COMPLETED
Conditions: Using NCID Database to Assess the Safety of Olaparib in Chinese Patients With Ovarian Cancer by Examining the Incidence, Seriousness, and Severity of All AE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of Selinexor With or Without Pembrolizumab Versus Standard of Care in Previously Treated Metastatic Colorectal Cancer With RAS Mutations
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Selinexor|DRUG: Pembrolizumab|DRUG: Trifluridine|DRUG: Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Study of Combined Sequential Chemotherapy and Radiation Therapy for Early-stage NK/T-cell Lymphoma
Status: RECRUITING
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: Sintilimab+Pegaspargase|DRUG: P-GemOx|DRUG: GELAD|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Protein, Core Muscle Rehab, Muscular Electrostimulation in Prolonged Mechanical Ventilation
Status: RECRUITING
Conditions: Prolonged Mechanical Ventilation|Protein Deficiency
Interventions: DIETARY_SUPPLEMENT: UC + high protein diet (HP)|BEHAVIORAL: UC + HP + core muscle rehabilitation|DEVICE: UC + HP + core muscle rehabilitation + neuromuscular electric stimulation (NMES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy, Safety, and Tolerability of Sarizotan in Rett Syndrome With Respiratory Symptoms
Status: TERMINATED
Conditions: Rett Syndrome
Interventions: DRUG: Sarizotan low dose|DRUG: Sarizotan high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 In Combination With Paclitaxel In Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: SU011248|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan/Cisplatin Plus Simvastatin in Extensive Disease-Small Cell Lung Cancer (ED-SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcuma Xanthorriza Roxb. 10% Cream for Melasma
Status: RECRUITING
Conditions: Melasma
Interventions: DRUG: 10% Curcuma xanthorriza Roxb.|DRUG: 2% Kojic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Personal Protective Equipment
Interventions: DEVICE: Personal protective equipment (PPE)|DEVICE: No Personal protective equipment (PPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Dual Task and Gait Speed on Gait Variability in Patients With Chronic Ankle Instability
Status: UNKNOWN
Conditions: Chronic Instability of Joint
Interventions: OTHER: Gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Vonoprazan|DRUG: Amoxicillin, Metronidazole|DRUG: Bismuth Potassium Citrate|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glyburide and Metformin Hydrochloride Tablets 5 mg/500 mg|DRUG: CLUCOVANCE® 5 mg/500 mg Tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Ramucirumab Plus Irinotecan for Previously Treated Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastro-esophageal Junction Adenocarcinoma
Interventions: DRUG: Irinotecan|DRUG: Ramucirumab|GENETIC: Blood for angiome profiling|GENETIC: Blood for cfDNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alisklamp and Dorsal Slit Sleeve Circumcision
Status: COMPLETED
Conditions: Circumcision
Interventions: DEVICE: Alisklamp|OTHER: Dorsal slit circumcision technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bilevel Positive Pressure Ventilation (BIPAP)in Patients With Sleep Disorders Breathing (SDB)and Congestive Heart Failure (CHF):Comparison of Two Diagnostic Methods
Status: UNKNOWN
Conditions: Symptomatic Congestive Heart Failure
Interventions: DEVICE: watch-pat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell- Based Noninvasive Prenatal Testing (NIPT): Single Cell Prenatal Diagnosis (SCPD)
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: DIAGNOSTIC_TEST: Redraw for analysis of blood samples from healthy pregnant women
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rituximab, Temozolomide, and Methylprednisolone in Treating Patients With Recurrent Primary CNS Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: methylprednisolone|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Neoantigen Peptide Vaccine in the Treatment of Advanced NSCLC Progressed After EGFR-TKI Treatment
Status: RECRUITING
Conditions: NSCLC|EGFR Gene Mutation
Interventions: OTHER: neo-antigen vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Flamboyant 125/12 Association in the Treatment of Adults With Moderate Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Flamboyant 125/12|DRUG: Budesonide/formoterol 200/6|OTHER: Flamboyant 125/12 Placebo|OTHER: Budesonide/formoterol 200/6 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Addition of Elacestrant (Oral SERD) to Niraparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Hormone Receptor Positive HER-2 Negative Breast Cancer|Advanced or Metastatic Breast Cancer|BRCA1 Mutation|BRCA2 Mutation|PALB2 Gene Mutation
Interventions: DRUG: Niraparib + Elacestrant|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CATCH-R: A Rollover Study to Provide Continued Access to Rucaparib
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer|Ovarian Cancer|Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer|Other Solid Tumor
Interventions: DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan, Prednisone and Thalidomide Versus Melphalan and Prednisone in Elderly Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Breathing Maneuvers on the Oxygenation Supply of the Heart Assessed With MRI in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Oxygen|OTHER: Hyperventilation Breath-hold (HVBH)|OTHER: HVBH with Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Study to Evaluate the Analgesic Efficacy of XP21L in Subjects With Pain Following Bunionectomy Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: diclofenac potassium (XP21L)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effect of abobotulinumtoxinA in the Gastrocnemius Muscle to Improve Equinus and Plantar Fasciitis Pain
Status: UNKNOWN
Conditions: Plantar Fasciitis|Plantar Fasciitis, Chronic|Plantar Fasciitis of Both Feet
Interventions: DRUG: AbobotulinumtoxinA 300 UNT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol Patch as add-on to Antipsychotics in Patients With Schizophrenia, Schizoaffective or Schizophreniform Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders
Interventions: DRUG: Estradiol|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia
Status: COMPLETED
Conditions: Caregiver Burden|Lewy Body Disease|Stress|Skill, Coping
Interventions: BEHAVIORAL: VOCALE LBD+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Charcot-Marie-Tooth Disease|Inherited Peripheral Neuropathy
Interventions: OTHER: Web-based survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-Label Efficacy and Safety Study of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)
Status: COMPLETED
Conditions: CD55-deficient Protein-losing Enteropathy|CHAPLE
Interventions: DRUG: Pozelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Critical Care OptimizatIon of Albumin Ordering
Status: COMPLETED
Conditions: Critical Illness
Interventions: OTHER: Albumin Fluid Resuscitation Optimization Intervention|OTHER: Usual Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Residual Disease Post Allogeneic Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: DEC-C|DEVICE: MyeloSeq-HD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral BT-11 in Moderate to Severe Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: BT-11 880 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: No Cases of Delayed Intracranial Hemorrhage (d-ICH) Among Patients With Mild Traumatic Brain Injury (mTBI) on Oral Anticoagulation Therapy
Status: COMPLETED
Conditions: Traumatic Intracranial Hemorrhage|Traumatic Brain Injury
Interventions: OTHER: no intervention, only observational retrospective study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ranibizumab Therapy for Non-arteritic Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Nonarteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of LeGoo™ Internal Vessel Occluder Versus Traditional Vessel Loops
Status: UNKNOWN
Conditions: Off Pump Coronary Artery Bypass Surgery
Interventions: DEVICE: LeGoo|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Discomforts in Critically Ill Patients: the IPREA3 Study
Status: COMPLETED
Conditions: Critical Illness
Interventions: OTHER: Administration of the IPREA3 questionnaire|OTHER: Immediate feedback through electronic reminder messages|OTHER: Targeted interventions in each ICU to reduce discomforts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chiropractic Care for Episodic Migraine
Status: NOT_YET_RECRUITING
Conditions: Episodic Migraine
Interventions: PROCEDURE: Chiropractic Care|BEHAVIORAL: Headache Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Impact of Routine Measurement of Cardiac Troponin (hsTnT) on Outcome in Elderly Patients Undergoing Major Surgery
Status: UNKNOWN
Conditions: Surgery--Complications|Mortality|Elderly
Interventions: DIAGNOSTIC_TEST: level of cardiac troponin|DIAGNOSTIC_TEST: diastolic function assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PD 0332991 and Cetuximab in Patients With Incurable SCCHN
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell of Head and Neck
Interventions: BIOLOGICAL: Cetuximab|DRUG: PD 0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prolonged-release Fampridine as Adjunct Therapy to Active Motor Training in MS Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: extended release fampridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy
Status: WITHDRAWN
Conditions: Gastrostomy|Ventilatory Failure|Respiratory Failure
Interventions: DEVICE: TPUG|PROCEDURE: PEG|PROCEDURE: PRG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Creative Dance Based Exercise Training on Respiratory, Balance and Cognitive Functions, Respiratory and Peripheral Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: Conventional Chest Physiotherapy|OTHER: Creative Dance Based Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Right Hemicolectomy with D2 lymph node dissection|PROCEDURE: Right Hemicolectomy with D3 lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels
Status: COMPLETED
Conditions: Healthy Volunteers|Hypercholesterolaemia
Interventions: DRUG: NNC0385-0434|DRUG: Placebo (NNC0385-0434)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
Status: RECRUITING
Conditions: Kidney Diseases|Kidney Failure, Chronic|Diabetic Nephropathy|Lupus Nephritis|Glomerulonephritis, IGA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Angioplasty in Peripheral Arterial Disease and Endothelial Function
Status: COMPLETED
Conditions: Peripheral Arterial Obstructive Disease|Intermittent Claudication
Interventions: PROCEDURE: Endovascular Revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Opioid Withdrawal Syndrome
Interventions: DRUG: Morphine|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FACE for Children With Rare Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Rare Diseases
Interventions: BEHAVIORAL: FAmily CEntered (FACE) pACP Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment With Radiofrequency in Patients With Chronic Pelvic Pain and History of Endometriosis
Status: UNKNOWN
Conditions: Endometriosis|Chronic Pain|Quality of Life
Interventions: DEVICE: Radiofrequency A|DEVICE: Radiofrequency B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
Status: RECRUITING
Conditions: Knee Injuries
Interventions: DEVICE: Endobutton CL BTB|DEVICE: Metal interference screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir/Emtricitabine With Doxycycline for Combination HIV and Syphilis Pre-exposure Prophylaxis in HIV-negative MSM
Status: COMPLETED
Conditions: HIV|Syphilis
Interventions: DRUG: Doxycycline 100mg PO daily x 12 months|DRUG: Tenofovir/emtricitabine 200/300mg PO daily|DRUG: Doxycycline 100mg PO daily x 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Individualized P2Y12 Receptor Antagonists Treatment Based on Agregometry Versus Fixed Dose Regimen in Patients After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Coronary Syndrome|STEMI|NSTEMI - Non-ST Segment Elevation MI|PLATELET AGGREGATION|INDIVIDUALIZED THERAPY
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramosetron, Aprepitant, and Dexamethasone Versus Palonosetron, Aprepitant, and Dexamethasone
Status: COMPLETED
Conditions: Cancer|Tumors
Interventions: DRUG: ramosetron, aprepitant, dexamethasone|DRUG: palonosetron, aprepitant, dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of AUY922 in NSCLC Patients With Exon 20 Insertion Mutations in EGFR
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: AUY922
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer|Precancerous Condition
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Cohort Study of Synovial Biomarkers in the Diagnosis and Prediction of Periprosthetic Joint Infection
Status: NOT_YET_RECRUITING
Conditions: Prospective Cohort Study of Synovial Biomarkers in the Diagnosis and Prediction of Periprosthetic Joint Infection
Interventions: DEVICE: Joint aspiration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Group Lifestyle Balance™ for Individuals With Traumatic Brain Injury (GLB-TBI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Group Lifestyle Balance™|OTHER: Attention Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction
Status: NOT_YET_RECRUITING
Conditions: Molar, Third|Temporomandibular Joint Disorders|Dry Socket|Coenzyme Q10
Interventions: DRUG: Coenzyme Q10 100 MG Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Omentopexy During Laparoscopic Insertion of Peritoneal Dialysis Catheter
Status: COMPLETED
Conditions: Mechanical Complication of Peritoneal Dialysis Catheter
Interventions: OTHER: Prophylactic laparoscopic omentopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D and Adipose Tissue Inflammation
Status: COMPLETED
Conditions: Vitamin D Deficiency|Obesity|Type 2 Diabetes Mellitus|Intestinal Permeability
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Matrix on Fruit Constituent Bioavailability
Status: COMPLETED
Conditions: Healthy Non-smoker
Interventions: DIETARY_SUPPLEMENT: Milk-based Strawberry Beverage without meal|DIETARY_SUPPLEMENT: Water-Based Strawberry Beverage without meal|DIETARY_SUPPLEMENT: Milk-based strawberry Beverage with meal|DIETARY_SUPPLEMENT: Water-Based strawberry Beverage with meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: EEG Patterns in Patients With Acute Ischemic Stroke Resulted From Large Vessels Occlusion in the Anterior Circulation
Status: UNKNOWN
Conditions: Stroke, Ischemic
Interventions: DIAGNOSTIC_TEST: Electroencephalography (EEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Mucositis in Patients Receiving Radiation Therapy for Cancer of the Mouth, Pharynx, or Larynx
Status: COMPLETED
Conditions: Head and Neck Cancer|Oral Complications
Interventions: PROCEDURE: management of therapy complications|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Antihypertensive Drugs in Patients With Hypertension and Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Hypertension
Interventions: DRUG: Olmesartan and Azelnidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult
Status: SUSPENDED
Conditions: Gram-Negative Bacterial Infections|Sepsis
Interventions: DRUG: GR270774
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Selinexor (KPT-330) and Liposomal Doxorubicin For Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Liposomal doxorubicin|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Human Milk Cream to Decrease Length of Stay in Extremely Premature Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: DIETARY_SUPPLEMENT: Cream Supplement group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Treatment of Stress and Anxiety in Myocardial Infarction With Non-obstructive Coronary Arteries
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Internet-based CBT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fingolimod in Patients With Relapsing-remitting Multiple Sclerosis With Optional Extension Phase
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fingolimod 1.25 mg|DRUG: Fingolimod 0.5 mg|DRUG: Interferon β-1a 30 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Capecitabine, and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease
Status: RECRUITING
Conditions: Peripheral Artery Disease|Atherosclerosis|Arterial Disease
Interventions: DEVICE: MagicTouch PTA sirolimus drug coated balloon (DCB)|DEVICE: POBA standard balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Alprazolam Extended-Release Tablets 3 mg to Xanax XR® Tablets 3 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alprazolam Extended-Release Tablets 3 mg|DRUG: Xanax XR® Tablets (3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Corneal Confocal Microscopy for the Identification and Prediction of Neuropathy in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Diabetes Complications
Interventions: OTHER: Exposure: Corneal nerve fibre morphology by the CCM Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trastuzumab (Herceptin), Paclitaxel, Carboplatin and Gemcitabine in Advanced Urothelial Cancer
Status: COMPLETED
Conditions: Urologic Neoplasms
Interventions: DRUG: Trastuzumab|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ideal Dosage for Sedation of Obese Patients Undergoing Knee or Hip Arthroplasty Under Spinal Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Arthritis Knee|Arthritis Hip
Interventions: DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Double-blind Active vs. Placebo Clinical Trial on the Effect of a Food Supplement on IBS in Children
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Verum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure
Status: RECRUITING
Conditions: Acute Respiratory Failure|Hypercoagulability|Fibrinolysis Shutdown
Interventions: DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplementing Intracytoplasmic Sperm Injection Handling Medium With Cytochalasin B
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Cytochalasin B use in ICSI handling medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mitral Valve Management During Septal Myectomy
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: Septal myectomy|PROCEDURE: alfieri stich|PROCEDURE: Subvalvular intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety of GSK573719 and GW642444 Administered Individually and Concurrently, With Verapamilin in Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719|DRUG: GW573719/GW573719
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes|Non-hodgkin Lymphoma|Hodgkin Lymphoma|Acquired Aplastic Anemia|Sickle Cell Disease
Interventions: OTHER: Donor Search Prognosis Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Relapsing Clostridium Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: OTHER: Fecal microbiota transplantation|DRUG: Fidaxomicin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIT in Insulin-resistant and Insulin-sensitive Obese Adolescents
Status: COMPLETED
Conditions: Obesity|Insulin-resistant|Adolescents
Interventions: OTHER: Group Insulin-Resistant|OTHER: Group Insulin-Sensitive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Experience Study of Deoxycholic Acid Injection
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Deoxycholic Acid Injection|DRUG: Placebo|OTHER: Cold Compress|DRUG: Lidocaine / Epinephrine|DRUG: Loratadine|DRUG: Ibuprofen|OTHER: Compression Chin Strap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy
Status: COMPLETED
Conditions: Breast Cancer|Mastectomy|Anesthesia, Local|Narcotic Use
Interventions: DRUG: regional nerve block with local anesthesia of bupivacaine with steroid|OTHER: Placebo regional nerveblock with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone and Dexmedetomidine as Adjuvants to Ropivacaine in Ultrasound-guided Multilevel Thoracic Paravertebral Block for Lobectomy: A Prospective, Randomized, Triple-blind Study
Status: UNKNOWN
Conditions: Dexamethasone|Dexmedetomidine|Ropivacaine|Lobectomy
Interventions: DRUG: dexamethasone; dexmedetomidine; ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BMS-986253 in Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Deoxyribonucleic acid (DNA) methyltransferase inhibitors (DNMTi) Decitabine|DRUG: Deoxyribonucleic acid (DNA) methyltransferase inhibitors (DNMTi) Cedazuridine|DRUG: BMS-986253|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DRUG: Cilostazol Tablet 100 mg|DRUG: PMR Tablet 135 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Femoroacetabular Impingement Treatment
Status: UNKNOWN
Conditions: Femoroacetabular Impingement
Interventions: PROCEDURE: Arthroscopic treatment of femoroacetabular impingement|OTHER: Physiotherapy and activity modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: Aliskiren 75 mg|DRUG: Aliskiren 150 mg|DRUG: Aliskiren 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnant Obese Women and Fetal Ultrasound Quality.
Status: UNKNOWN
Conditions: Obese Women|Pregnant Women
Interventions: DEVICE: ultrasound propagation velocities, ultrasound fetal quality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer
Status: RECRUITING
Conditions: Gastric or Esophagogastric Junction Adenocarcinoma
Interventions: BIOLOGICAL: JS001/Placebo|BIOLOGICAL: JS001/placebo combine with Postoperative Adjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cluster-RCT of SHS Among Primary School Students
Status: COMPLETED
Conditions: Secondhand Smoke|Thirdhand Smoke|Smoking
Interventions: OTHER: Worksheets|OTHER: Whatsapp messages|OTHER: Online quizzes|OTHER: Leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Assessing Tolerability and Safety of AFFITOPE® PD03A in Patients With Early Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Neurodegenerative Diseases
Interventions: BIOLOGICAL: Low dose AFFITOPE® PD03A + Adjuvant|BIOLOGICAL: High dose AFFITOPE® PD03A + Adjuvant|BIOLOGICAL: Adjuvant without active component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of KC1036 Versus Investigator's Choice of Chemotherapy in Patients With Advanced Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: KC1036|DRUG: Irinotecan|DRUG: Docetaxel|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT