pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Nicotine Dependence
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Diagnostic Performance of C-Tb to QuantiFERON®-TB, in Combination With a Safety Assessment of C-Tb vs Tuberculin PPD RT23 SSI
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: C-Tb|BIOLOGICAL: 2 T.U. Tuberculin PPD RT 23 SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Isatuximab in Lung Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Antibody-mediated Rejection|Allosensitization
Interventions: DRUG: Isatuximab|PROCEDURE: bone marrow biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SLV 308 and Pramipexole for Treatment of Patients With Early Parkinson Disease
Status: COMPLETED
Conditions: Early Stage Parkinson Disease
Interventions: DRUG: Pardaprunox|DRUG: pramipexole|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histological Study of the Effects of a 2910 nm Fiber Laser Technology
Status: ENROLLING_BY_INVITATION
Conditions: Skin Laxity
Interventions: DEVICE: 2910 nm Fiber Laser Treatment; Pre-Clinical Histology Evaluation|DEVICE: 2910 nm Fiber Laser Treatment; Part 2 Histology Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial to Assess Safety, Efficacy, Tolerability and Immunogenicity of Influenza Virus Vaccine, Liquid Formulation (CAIV-T), Administered Concomitantly With a Combination Live, Attenuated, Mumps, Measles, and Rubella Vaccine in Healthy Children Aged 11 - 24 Months
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: CAIV-T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Time to Protection and Adherence Requirements of Raltegravir With or Without Lamivudine in Protection From HIV Infection
Status: COMPLETED
Conditions: Hiv
Interventions: DRUG: Raltegravir 400Mg Tab|DRUG: Lamivudine 150Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use Disorders|Drug Abuse|Alcohol Abuse|Posttraumatic Stress Disorder|PTSD|Recidivism|Depression
Interventions: BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypolipidemic and Antioxidant Capacity of Spirulina and Exercise
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Supplementation with Spirulina maxima|OTHER: Washout|OTHER: Supplementation with placebo|OTHER: Isoenergetic diet|OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TQB2450 Plus Anlotinib as Adjuvant Therapy in HCC Patients at High Risk of Recurrence After Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Adjuvant Therapy
Interventions: DRUG: TQB2450 injection|DRUG: Anlotinib hydrochloride capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety of Combining Lutathera(R) and Azedra(R) to Treat Mid-gut Neuroendocrine Tumors
Status: WITHDRAWN
Conditions: Gastro-enteropancreatic Neuroendocrine Tumor|Neuroendocrine Tumors
Interventions: DRUG: Lutathera|DRUG: Azedra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-course Antibiotics vs Standard Course Antibiotics in Patients With Cholangitis
Status: RECRUITING
Conditions: Cholangitis
Interventions: DRUG: cefrtriaxone, gentamicin, cefuroxim, ciprofloxin or other antibiotics according to local guideline (24 hours)|DRUG: cefrtriaxone, gentamicin, cefuroxim, ciprofloxin or other antibiotics according to local guideline (4 to 7 days)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cefazolin-Lidocaine Combination Solution to Reduce Antibiotic Pain
Status: UNKNOWN
Conditions: Vitreoretinal Surgery|Endophthalmitis
Interventions: DRUG: Cefazolin|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Japanese Male Study Participants
Status: COMPLETED
Conditions: Healthy Study Participants
Interventions: DRUG: brivaracetam (BRV) tablet|DRUG: brivaracetam (BRV) dry syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Efficacy of Topical Squaric Acid Dibutyl Ester in Children and Adolescents With Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Placebo|DRUG: SADBE 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Grass Pollen-derived Peptides to Treat Seasonal Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: gpASIT+TM|BIOLOGICAL: Placebo|BIOLOGICAL: gpASIT+TM|BIOLOGICAL: gpASIT+TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Using a Genomic Predictor of Platinum Resistance to Guide Therapy in Stage IIIB/IV Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Cisplatin & Gemcitabine|DRUG: Cisplatin & Pemetrexed|DRUG: Docetaxel & Gemcitabine|DRUG: Pemetrexed & Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Malignant Neoplasm in the Bone|Metastatic Malignant Neoplasm in the Lymph Nodes|Metastatic Malignant Neoplasm in the Soft Tissues|Metastatic Malignant Neoplasm in the Viscera|Sarcomatoid Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cabozantinib|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis|Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: ExoFlo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 FlexPen® in Insulin Naive Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer
Status: COMPLETED
Conditions: Nonmalignant Neoplasm|Prostate Cancer
Interventions: DRUG: dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia
Status: UNKNOWN
Conditions: Hernias Inguinal Reducible|Local Anaesthesia
Interventions: PROCEDURE: Desarda's technique|PROCEDURE: Lichtenstein's technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Entacapone for Methamphetamine Abuse
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Entacapone|DRUG: Methamphetamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Atezolizumab in Large Cell Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Large Cell Neuroendocrine Carcinoma of the Lung
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pain Control in Transurethral Resection of the Prostate
Status: RECRUITING
Conditions: Pain|BPH With Urinary Obstruction|BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Interventions: DRUG: Ibuprofen 600 mg|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of the Ebola Chimpanzee Adenovirus Vector Vaccine (cAd3-EBO), VRC-EBOADC069-00-VP, in Healthy Adults
Status: COMPLETED
Conditions: Healthy Adult Immune Responses to Vaccine
Interventions: BIOLOGICAL: VRC-EBOADC069-00-VP|BIOLOGICAL: VRC-EBOADC076-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AGN-229666 for the Treatment of Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AGN-229666|OTHER: vehicle of AGN-229666
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Hydroxychloroquine in Patients With SARS-CoV-2 (COVID-19)
Status: WITHDRAWN
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipoprotein a is an Independent Risk Factor for Overall Survival in Patients With Pancreatic Cancer: a Propensity Score Matching Analysis
Status: RECRUITING
Conditions: Pancreatic Carcinoma; Lipoprotein a; Overall Survival; Prognosis
Interventions: OTHER: Lp(a)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceptance and Commitment Therapy Based Psychoeducation, Meaning of Life and Coping Skills in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Coping Skills
Interventions: OTHER: Psychoeducation based on Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP)
Status: WITHDRAWN
Conditions: Hyperaldosteronism|Renal Insufficiency
Interventions: DIETARY_SUPPLEMENT: Hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Docetaxel and Carboplatin in HER2 Positive Breast Cancer Patients.
Status: COMPLETED
Conditions: HER2 Positive Breast Cancer
Interventions: DRUG: Pyrotinib plus trastuzumab and docetaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization vs. Pharmacotherapy for LUTS/BPH
Status: NOT_YET_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Pharmacotherapy|Prostatic Artery Embolization|Minimally Invasive Treatment
Interventions: PROCEDURE: Prostatic Artery Embolization (PAE)|DRUG: Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With NLY01 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: NLY01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Natalizumab in Combination With Avonex in the Treatment of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Natalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Combined With Targeted Therapy and Chemotherapy With or Without Radiotherapy as First-Line Treatment for Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Colorectal Carcinoma|Immunotherapy
Interventions: DRUG: Toripalimab|DRUG: Chemotherapy|RADIATION: SABR|DRUG: Targeted therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Tolerability and Effects of AZD8848 in Allergic Asthma Subjects Challenged With Inhaled Allergen
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: AZD8848|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a New Strategy to Identify HNPCC Patients
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Hereditary Nonpolyposis Colorectal Cancer
Interventions: BEHAVIORAL: Education for professionals|BEHAVIORAL: Distribution of educational materials|BEHAVIORAL: Feedback for professionals|BEHAVIORAL: Reminders for professionals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Facing Obstacles to RDI (Relative Dose Intensity) Through Telephone Intervention Strategy
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: OTHER: Telephone Intervention|OTHER: Usual Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glycosade v UCCS in the Dietary Management of Hepatic GSD
Status: COMPLETED
Conditions: Glycogen Storage Disease
Interventions: DIETARY_SUPPLEMENT: Medical Food - Glycosade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of "Quantum Touch" Application on Transfer Anxiety in Pediatric Patients and Their Parents Planned to be Hospitalized in the Emergency Department
Status: RECRUITING
Conditions: Anxiety|Child, Only|Emergencies
Interventions: OTHER: Quantum Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of TSTVs NT Along With Conventional Therapy for Upper Limb Motor Function Among Chronic Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Task Specific Training|DIAGNOSTIC_TEST: Neurodevelopmental Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study To Determine If Coadministration Of Tamoxifen Alters The Extent Or Rate Of Palbociclib (PD-0332991) Absorption Or Elimination In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PD-0332991 alone|DRUG: Tamoxifen 60 mg|DRUG: Tamoxifen 20 mg|DRUG: PD-0332991 combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Progressive Splinting Status Post Elbow Fractures and Dislocations
Status: TERMINATED
Conditions: Upper Extremity Fracture|Upper Extremity Dislocation|Fractures, Comminuted|Elbow Fracture|Elbow Dislocation
Interventions: DEVICE: JAS Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Cardiac Shockwave Therapy in Patients Undergoing Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Heart Failure Patients|Cardiac Ischemia
Interventions: DEVICE: Shockwave Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Anesthesia|Analgesia|Acute Pain|Patient Controlled Analgesia
Interventions: PROCEDURE: Subcostal Anterior Quadratus Lumborum Block|PROCEDURE: Thoracic Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2b/3 Trial of VSV-ΔG SARS-CoV-2 Vaccine (BRILIFE) Against Approved Comparator Vaccine.
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: IIBR-100|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Veltuzumab (hA20) at Different Doses in Patients With ITP
Status: TERMINATED
Conditions: Purpura, Thrombocytopenic, Idiopathic|Autoimmune Thrombocytopenic Purpura|Purpura, Thrombocytopenic, Autoimmune
Interventions: BIOLOGICAL: veltuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Comparison of Steroid or Placebo in Combination With Salmeterol and Tiotropium in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Salmeterol|DRUG: Fluticasone|DRUG: Ciclesonide low|DRUG: Ciclesonide high|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of SLITone(TM) Birch in Subjects With Hayfever
Status: COMPLETED
Conditions: Allergy
Interventions: BIOLOGICAL: Sublingual immunotherapy|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GOS Prebiotic Effect in Children Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Galactooligosaccharide prebiotic|DRUG: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plasmafit® Revision Structan® Hip Endoprosthesis Cup
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteolysis|Arthroplasty Complications|Instability of Prosthetic Joint|Degenerative Osteoarthritis|Rheumatic Arthritis|Fractures, Hip|Femoral Head Avascular Necrosis|Prosthesis Failure
Interventions: DEVICE: Plasmafit® Revision Structan®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Head and Neck Squamous Cell Carcinoma|Voice Disorders|Laryngeal Cancer
Interventions: DRUG: Hyaluronic acid|OTHER: No Hyaluronic Acid Injection Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fullerene in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .
Status: NOT_YET_RECRUITING
Conditions: Radiation Dermatitis
Interventions: OTHER: Fullerene cream|DRUG: Trolamine (Biafine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma
Status: TERMINATED
Conditions: Glioblastoma (GBM)|DIPG|Brainstem Glioma, Pediatric|Diffuse Spinal Glioma|Bilateral Thalamic Glioma|Gliomatosis Cerebri|Anaplastic Astrocytoma|Midline Diffuse Glioma
Interventions: DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Arthroplasty Complications
Interventions: BEHAVIORAL: Treadmill-based perturbation training|BEHAVIORAL: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Long-term Clinical Outcomes and Patterns of Transfusion in PCI Patients: Retrospective Cohort Study
Status: COMPLETED
Conditions: Erythrocyte Transfusion|Percutaneous Coronary Intervention|Revascularization
Interventions: PROCEDURE: No intervention is required due to retrospective observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Health Effects of Biodiesel Exhaust Exposure
Status: COMPLETED
Conditions: Vascular Endothelium
Interventions: OTHER: Forearm venous occlusion plethysmography study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Assess Safety, Tolerability, and Efficacy of Anti-GPRC5D-CD19-CAR-T in Relapsed/Refractory Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: infusion of GPRC5D-CD19 CAR T injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of C0-C1 Mobilization in the Neutral Position in Subjects With Upper Cervical Rotational Hypomobility
Status: COMPLETED
Conditions: Upper Cervical Spine Rotational Hypomobility
Interventions: OTHER: C0-C1 dorsal glide manual mobilization|OTHER: C7-T1 ventral cranial glide manual mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis
Status: TERMINATED
Conditions: Head and Neck Cancer|Breast Cancer
Interventions: OTHER: Aveeno cream|OTHER: Flamazine cream|OTHER: NeoVIDERM cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Understanding Dexmedetomidine In Infants Post-Operative From Cardiac Surgery
Status: COMPLETED
Conditions: Hypoplastic Left Heart|Tetralogy of Fallot|Tricuspid Atresia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxol® in Monotherapy or in Combination With Topotecan or Carboplatin in Patients With Epithelial Ovarian Cancer in Early Relapse
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Malignant Tumor of Peritoneum
Interventions: DRUG: Paclitaxel|DRUG: Topotecan|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Efficacy of Intravenous Carbetocin Versus Intramyometrial Injection of Adrenaline in Reducing Blood Loss
Status: COMPLETED
Conditions: Uterine Fibroid
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation|Post-pericardiotomy Syndrome|Constriction
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Assessment of Cardiovascular Endurance Training for the Symptomatic Improvement of Irritable Bowel Syndrome Patients With a Sedentary and Non-active Lifestyle.
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Cardiovascular endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Treatment in Inclusion Body Myositis
Status: NOT_YET_RECRUITING
Conditions: Inclusion Body Myositis, Sporadic
Interventions: DRUG: Ruxolitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restenosis Intrastent: Bioresorbable Vascular Scaffolds Treatment With Scoring Balloon Pre-dilatation (RIBS VI Scoring)
Status: UNKNOWN
Conditions: Coronary In-stent Restenosis
Interventions: DEVICE: Bioresorbable vascular scaffold. Absorb GT1 (Abbott)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.
Status: TERMINATED
Conditions: Wet Macular Degeneration
Interventions: DRUG: KSI-301|DRUG: Aflibercept|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib Pre-, During- and Post-HSCT for Patients With Primary or Secondary Myelofibrosis.
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness, Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery
Status: COMPLETED
Conditions: Inguinal and Ventral Hernia Repair by Sublay, Underlay and IPOM Mesh Fixation
Interventions: PROCEDURE: Experimental medical device|PROCEDURE: Comparator medical device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Focal Muscle Vibration on Upper Limb Function in Subacute Post-stroke Patients
Status: COMPLETED
Conditions: Stroke, Subacute
Interventions: OTHER: Conventional Treatment|OTHER: Focal Muscle Vibration (120Hz)|OTHER: Focal Muscle Vibration (60Hz)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Synbiotics Effects in Polycystic Ovary Syndrome: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: PCOS- Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: synbiotics|COMBINATION_PRODUCT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Focal Therapy for Prostate Cancer - A Pilot Study of Focal Low Dose Rate Brachytherapy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Low Dose Radiation Focal Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Immediate Instillation of EO9 After TURBT in Patients With Non-muscle-invasive Bladder Cancer (NMIBC)
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: EO9 (Apaziquone)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Allium Hookeri on Blood Glucose
Status: COMPLETED
Conditions: PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Allium hookeri extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Medications vs. Patch Alone for Medically-Ill Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine patch, nicotine inhaler, bupropion|DRUG: Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers
Status: COMPLETED
Conditions: Advanced Malignant Neoplasm|Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm|Refractory Malignant Neoplasm
Interventions: BIOLOGICAL: Anakinra|BIOLOGICAL: Denosumab|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Peri-operative Pain Management in Pediatric Open Pyeloplasty Cases
Status: UNKNOWN
Conditions: Anesthesia and Analgesia|Pediatrics|Urologic Surgical Procedures
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
Status: TERMINATED
Conditions: Polycystic Ovary Syndrome|In Vitro Fertilization
Interventions: OTHER: Controlled ovarian hyperstimulation for IVF with a long agonist protocol|OTHER: Controlled ovarian hyperstimulation for IVF with an antagonist protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Warfarin Versus Aspirin Recurrent Stroke Study
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Active Aspirin|DRUG: Active Warfarin|DRUG: Aspirin placebo|DRUG: Warfarin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and PK of Nikkomycin Z for Coccidioides Pneumonia Treatment
Status: TERMINATED
Conditions: Coccidioidomycosis
Interventions: DRUG: nikkomycin Z
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HUMAN CHORIONIC GONADOTROPIN (HcG) VS MAGNESIUM SULPHATE (MgSo4) AS A TOCOLYTIC AGENT- A RANDOMIZED CONTROLLED TRIAL
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DRUG: human chorionic gonadotropin (hCG)|DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sex Differences in Myocardial Steatosis Induced Left Ventricular Dysfunction
Status: RECRUITING
Conditions: Heart Diseases|Left Ventricular Dysfunction
Interventions: DRUG: Estradiol patch|DRUG: Cetrotide|OTHER: Fasting|OTHER: Lower Body Negative Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Virtual Reality Rehabilitation and Muscle Energy Technique in Patients With Patellofemoral Pain Syndrome.
Status: RECRUITING
Conditions: Patellofemoral Pain Syndrome|Knee Pain Chronic
Interventions: OTHER: Virtual Reality technique|OTHER: Muscle energy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Difficult Biliary Cannulation in Patients With Distal Malignant Biliary Obstruction: an Underestimated Problem
Status: COMPLETED
Conditions: Biliary Condition
Interventions: PROCEDURE: Endsocopic Retrograde ColangioPancreatography (ERCP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DEVICE: Apollo ESG with ERBE HAPC|DEVICE: Apollo ESG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Duloxetine in the Reduction of Pain in Patient With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Cymbalta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure vs Those Determined by Polysomnography
Status: COMPLETED
Conditions: Sleep Apnea Syndromes
Interventions: DEVICE: Continuous Positive Airway Pressure|DEVICE: Polysomnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CXCL10 As a Biomarker Of ILD in Patients WithRA
Status: UNKNOWN
Conditions: Interstitial Lung Disease in Patients With Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: serum cxcl10 by ELISA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp
Status: RECRUITING
Conditions: Scarring
Interventions: PROCEDURE: Pinch Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Abnormal Uterine Bleeding|Uterine Bleeding|Fibroid Uterus|Surgery
Interventions: PROCEDURE: Total Laparoscopic Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Brachytherapy (eBx)-Mohs Matched Pair - Cohort Study A Multi-Center Retrospective-Prospective Matched Pairs Cohort Study to Assess Long-term Clinical Outcomes of Non-melanoma Skin Cancer Patients Treated With eBx Compared to Non-melanoma Skin Cancer Patients Treated With Mohs Surgery
Status: UNKNOWN
Conditions: Nonmelanoma Skin Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stereotactic Radiotherapy Combined With Chemotherapy or Not for Treatment of Oligometastases in HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Chemotherapy|RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients?
Status: COMPLETED
Conditions: Adrenal Insufficiency|Cirrhosis|Spur Cell Anemia|Lecithin Acyltransferase Deficiency
Interventions: DRUG: Cosyntropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: dextromethorphan hydrobromide|DRUG: tamoxifen citrate|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies|OTHER: pharmacological study|PROCEDURE: fluorescence imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Incidence of Gallstones After Gastrectomy
Status: RECRUITING
Conditions: Gallstone|Gastric Cancer
Interventions: PROCEDURE: Distal gastrectomy and radical resection|PROCEDURE: Total gastrectomy and radical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection for Treatment of Vaginismus
Status: UNKNOWN
Conditions: Vaginismus
Interventions: DRUG: botulinum toxin|DRUG: botulinum toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission
Status: UNKNOWN
Conditions: Chronic Myelogenous Leukemia|Short Stature
Interventions: DRUG: Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mental Health and Well-being of People Who Seek Help From Their Member of Parliament
Status: COMPLETED
Conditions: Common Mental Disorders|Alcohol Use Disorder
Interventions: DIAGNOSTIC_TEST: 12-item General Health Questionnaire (GHQ-12)|DIAGNOSTIC_TEST: WHO AUDIT (World Health Organization- Alcohol Use Disorders Inventory Tool)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Idiopathic Intracranial Hypertension Treatment Trial
Status: TERMINATED
Conditions: Idiopathic Intracranial Hypertension
Interventions: DRUG: Acetazolamide|PROCEDURE: Optic Nerve Sheath Fenestration|PROCEDURE: Ventriculoperitoneal CSF Shunting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults
Status: RECRUITING
Conditions: Accidental Fall
Interventions: BEHAVIORAL: Virtual tai ji quan: moving for better balance intervention (V-TJQMBB)|BEHAVIORAL: Virtual multimodal exercise intervention (V-Multimodal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
Status: COMPLETED
Conditions: Anaplastic Astrocytoma|Anaplastic Ependymoma|Anaplastic Meningioma|Anaplastic Oligodendroglioma|Brain Stem Glioma|Ependymoblastoma|Giant Cell Glioblastoma|Glioblastoma|Gliosarcoma|Grade III Meningioma|Meningeal Hemangiopericytoma|Mixed Glioma|Pineal Gland Astrocytoma|Brain Tumor
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|BIOLOGICAL: aldesleukin|OTHER: laboratory biomarker analysis|PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Head and Neck Cancer|Recurrent Head and Neck Cancer|HPV Positive Oropharyngeal Squamous Cell Carcinoma|Neoplasms, Head and Neck
Interventions: COMBINATION_PRODUCT: Pembrolizumab (KEYTRUDA®) and PDS0101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Transverse Planes Technique in the Diaphragmatic Region in Young Subjects.
Status: NOT_YET_RECRUITING
Conditions: Healthy|Diaphragm Issues
Interventions: OTHER: manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the PK, Safety, and Tolerability of BG00012 in Chinese, Japanese, and Caucasian Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BG00012 Dose 1|DRUG: BG00012 Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed/Refractory Acute Lymphoblastic Leukemia or Relapsed/Refractory Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia (ALL)|Lymphoblastic Lymphoma
Interventions: DRUG: Navitoclax|DRUG: Chemotherapy|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nocturnal Enuresis and Rapid Maxillary Expansion
Status: COMPLETED
Conditions: Nocturnal Enuresis
Interventions: DEVICE: Rapid Maxillary Expansion|DEVICE: Placebo Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lingdancao Granules in the Treatment of Seasonal Influenza
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Lingdancao granules|DRUG: analogous oseltamivir phosphate capsule|DRUG: Oseltamivir phosphate capsule|DRUG: analogous Lingdancao granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Non-invasive Index of Endothelial Function.
Status: COMPLETED
Conditions: Chest Pain|Major Adverse Cardiovascular Events
Interventions: DEVICE: Digital plethysmography in stratifying the cardiovascular risk for patients consulting for chest pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of APPA in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: APPA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Trial in Patients Who Are Undergoing Surgery for Early Stage Mouth Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: immunohistochemistry staining method|PROCEDURE: conventional surgery|PROCEDURE: lymphangiography|PROCEDURE: radionuclide imaging|PROCEDURE: sentinel lymph node biopsy|RADIATION: technetium Tc 99m sulfur colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Leber Hereditary Optic Neuropathy (LHON)
Interventions: DRUG: NR082 Injection|DEVICE: Injection needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bioavailability of Dexketoprofen-Vit B vs Dexketoprofen, in Healthy Subjects, Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dexketoprofen 25 MG|DRUG: Fixed dose Dexketoprofen-Vitamin B Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT