pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SPG Block for Acute Pediatric Migraine
Status: UNKNOWN
Conditions: Migraine in Children|Sphenopalatine Neuralgia|Migraine in Adolescence
Interventions: DRUG: Lidocaine topical|DRUG: Prochlorperazine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lower Limb Positive Pressure on the Balance of Community-dwelling Older Adults
Status: UNKNOWN
Conditions: Old Age|Fall
Interventions: OTHER: Normal treadmill|OTHER: Anti-gravity treadmill with lower limb positive pressure|OTHER: Anti-gravity treadmill with without lower limb positive pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Immunogenicity of Leucostim® Versus Neupogen® in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Leucostim 5µg/kg/day|BIOLOGICAL: Neupogen 5µg/kg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sjogren's Lung Study
Status: SUSPENDED
Conditions: Sjogren's Syndrome|Interstitial Lung Disease|Primary Pulmonary Lymphoma (Disorder)|Chronic Bronchiolitis|Bronchiectasis|Lung Diseases|Cystic Lung Disease|Lymphocytic Interst. Pneumonitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FV-EUS Endoscope Versus CLA-EUS for EUS-FNA of Solid Lesions
Status: COMPLETED
Conditions: Solid Lesions of the GI Tract or of Adjacent Organs
Interventions: DEVICE: EUS-guided fine needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Are Audiovisual Materials Superior to Printed Materials in Improving Awareness Among Type 2 Diabetic Patients?
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Audiovisual material "video"|OTHER: Printed material "brochure"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DEVICE: BreathID (Methacetin breath test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Neuroblastoma|Sarcoma
Interventions: DRUG: Iodine I 131 MOAB 8H9|DRUG: Iodine I 131 MOAB 8H9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XCHT for Irinotecan-Induced Gut Toxicities (Run-in Study)
Status: COMPLETED
Conditions: Malignant Tumor|Diarrhea
Interventions: DRUG: Xiao Chai Hu Tang (XCHT)|OTHER: Raloxifene|DRUG: FOLFIRI regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Determining the Preliminary Efficacy of the Emergency Department Delirium Screening and Detection Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium
Interventions: BEHAVIORAL: ED Delirium Screening and Detection Program (ED-DDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Intravenous Neridronic Acid in CRPS
Status: TERMINATED
Conditions: Complex Regional Pain Syndrome (CRPS)
Interventions: DRUG: Neridronic acid 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Visual Confusion Using Stereoscopic Displays
Status: COMPLETED
Conditions: Diplopia|Binocular Vision Suppression|Binocular; Fusion, With Defective Stereopsis|Monocular Diplopia
Interventions: BEHAVIORAL: Binocular visual confusion (unilateral opaque)|BEHAVIORAL: Unilateral monocular visual confusion (unilateral see-through)|BEHAVIORAL: Bilateral monocular visual confusion (bilateral see-through)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of an Implantable Functional Neuromuscular Stimulation System for Patients With Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: PROCEDURE: Surgery|DEVICE: IRS-8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
Status: UNKNOWN
Conditions: Gastrointestinal Vascular Malformation
Interventions: DEVICE: balloon assisted enteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Voclosporin and Tacrolimus in Transplantation
Status: WITHDRAWN
Conditions: Renal Transplantation
Interventions: DRUG: voclosporin|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis.
Status: COMPLETED
Conditions: GERD With Erosive Esophagitis
Interventions: DRUG: AZD0865
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Dysphoria
Status: RECRUITING
Conditions: Dysphoria
Interventions: DEVICE: Guided Meditation VR for Wellness|DEVICE: Accelerated Transcranial Magnetic Stimulation: Treatment A|DEVICE: Accelerated Transcranial Magnetic Stimulation: Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study Describing the Usual Clinical Practice Use of NovoSeven® in the Home Treatment of Joint Bleeds in Patients With Haemophilia A or B and Inhibitors
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A|Haemophilia B
Interventions: DRUG: activated recombinant human factor VII
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES)
Status: COMPLETED
Conditions: Urge Urinary Incontinence|Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Timing of Glaucoma Drainage Device With Boston Keratoprosthesis
Status: RECRUITING
Conditions: Corneal Transplantation|Glaucoma
Interventions: PROCEDURE: Boston keratoprosthesis type 1|PROCEDURE: Glaucoma drainage device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)_VA Only
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Muscle Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Recurrent Uveal Melanoma|Stage III Uveal Melanoma AJCC v7|Stage IIIA Uveal Melanoma AJCC v7|Stage IIIB Uveal Melanoma AJCC v7|Stage IIIC Uveal Melanoma AJCC v7|Stage IV Uveal Melanoma AJCC v7
Interventions: DRUG: Cabozantinib S-malate|DRUG: Dacarbazine|OTHER: Laboratory Biomarker Analysis|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Safety, Tolerability, and Immunogenicity of Three Dose Levels of ACAM3000 Smallpox Vaccine
Status: COMPLETED
Conditions: Smallpox
Interventions: DRUG: MVA Smallpox vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC-PC)
Status: TERMINATED
Conditions: Castration Resistant Prostate Cancer, CRPC
Interventions: BIOLOGICAL: Cellgram-DC-PC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Metabolism in Brown Adipose Tissue (BAT) in Young Healthy Men Evaluated by Deuterium Metabolic Imaging (DMI)
Status: TERMINATED
Conditions: Type2 Diabetes|Obesity|Metabolic Syndrome
Interventions: OTHER: cooling using a water-perfused vest|OTHER: thermoneutrality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of XmAb®2513 to Treat Hodgkin Lymphoma or Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Anaplastic Large Cell Lymphoma
Interventions: BIOLOGICAL: XmAb2513
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etomidate Induction in Hysteroscopic Surgery
Status: UNKNOWN
Conditions: Etomidate Induced Dose|Hysteroscopic Surgery
Interventions: DRUG: etomidate|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy
Status: RECRUITING
Conditions: Irreversible Pulpitis|Extremely Deep Caries|Partial Pulpotomy
Interventions: PROCEDURE: effect of 3% and 5% sodium hypochlorite on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia|Untreated Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: Daunorubicin Hydrochloride|OTHER: Pharmacological Study|DRUG: Prednisolone|DRUG: Prednisone|DRUG: Vincristine Sulfate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Atorvastatin in Perioperative Vascular Surgery - Pilot Study
Status: COMPLETED
Conditions: Vascular Surgery
Interventions: DRUG: Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Profile Changes and Torque Control in Dental Bimaxillary Proclination Cases Using Lingual Lever Arm Mechanics vs Conventional Lingual Orthodontic Mechanics A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Bimaxillary Proclination
Interventions: PROCEDURE: Lingual orthodontics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Calling the Patient's Name on Recovery From General Anesthesia
Status: COMPLETED
Conditions: Delayed Emergence From Anesthesia
Interventions: PROCEDURE: Calling the patient's name|PROCEDURE: Not calling the patient's name
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety, Tolerability, Efficacy and Pharmacokinetics of ASC10 in Mild to Moderate COVID-19 Patients
Status: NOT_YET_RECRUITING
Conditions: SARS CoV 2 Infection
Interventions: DRUG: ASC10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diets for Symptoms of Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: Ketone ester drink|DIETARY_SUPPLEMENT: Placebo (carbohydrate containing) drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Plant-based H5 Virus-Like Particles (VLP) Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Virus Diseases|RNA Virus Infections|Respiratory Tract Diseases|Respiratory Tract Infections
Interventions: BIOLOGICAL: H5 VLP pandemic influenza vaccine 5 µg|BIOLOGICAL: H5 VLP pandemic influenza vaccine 10 µg|BIOLOGICAL: H5 VLP pandemic influenza vaccine 20 µg|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-inferiority Study of the Pursuit of Enteral Nutrition Compared to a Strategy of Gastric Emptiness Peri-extubation. Cluster Randomized Trial
Status: COMPLETED
Conditions: Non-inferiority, in Terms of Extubation Failure, Continuation of Enteral Nutrition Before Extubation Versus Gastric Vacuity Peri-extubation
Interventions: OTHER: maintaining calorie intake|OTHER: maximum gastric vacuity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: OKG-0301 for the Treatment of Acute Adenoviral Conjunctivitis
Status: UNKNOWN
Conditions: Adenoviral Conjunctivitis
Interventions: DRUG: OKG-0301
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Attention Bias Modification (ABM)|BEHAVIORAL: Attention Control Condition (ACC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: maxillary sinus augmentation with CGF|DEVICE: "dynamic implant valve approach" - DIVA system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uptake to Colorectal Cancer Screening in Familial-risk Population
Status: COMPLETED
Conditions: Colorectal Cancer|Screening Uptake of Colonoscopy and FIT
Interventions: PROCEDURE: annual FIT and colonoscopy in case of a positive test|PROCEDURE: colonoscopy with sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A User-friendly, Non-invasive Neuro-orthosis That Restores Volitionally Controlled Grasp Functions for SCI Survivors With Tetraplegia
Status: RECRUITING
Conditions: Cervical Spinal Cord Injury
Interventions: DEVICE: NeuroLife EMG-FES Sleeve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Comparison of Bonding Failure Rates of Fixed Lingual Mandibular Retainers in a French Sample Aged 11 or Older, Comparing Prior Enamel Sandblasting With Conventional Pumice Polishing
Status: COMPLETED
Conditions: Detachment of Glued Mandibular Post-orthodontic Restraints
Interventions: PROCEDURE: Enamel pumicing before bonding the lingual retainer.|PROCEDURE: Enamel sandblasting before bonding the lingual retainer.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Efficacy of Shotblocker and Acupressure in Reducing Pain Due to Intramuscular Injection
Status: UNKNOWN
Conditions: Acute Pain|İnjection|Acupressure|Alternative Medicine
Interventions: OTHER: acupressure application|DEVICE: Shotblocher
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AVANTAGE® RELOAD Double Mobility Acetabular Cup -Clinical Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Osteoarthritis|Post-Traumatic Arthritis|Inflammatory Joint Disease|Femoral Neck Fracture|Femoral Head Necrosis|Sequelae From Previous Hip Surgery|Osteotomies|Congenital Hip Dysplasia
Interventions: OTHER: Avantage Reload cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Squamous Cell Carcinoma of the Head and Neck|Ovarian Cancer
Interventions: BIOLOGICAL: PF-07257876
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal Defects
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Drug-drug Interaction Study of SH229 Tablets and Daclatasvir Dihydrochloride Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: SH229|DRUG: SH229|DRUG: Daclatasvir dihydrochloride|DRUG: Daclatasvir dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Co-transplantation of MSC in the Setting of Allo-HSCT
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: BIOLOGICAL: Cotransplant with MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Ivacaftor in Cystic Fibrosis Subjects 2 Through 5 Years of Age With a CFTR Gating Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma Using Either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: OTHER: Fractional Carbon Dioxide Laser|OTHER: Microneedling using dermapen|OTHER: Triamcinolone Acetonide|OTHER: Platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma|Oropharyngeal Basaloid Carcinoma|Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Posterior Tongue Squamous Cell Carcinoma|Soft Palate Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7|Tonsillar Squamous Cell Carcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulated Driving Performance, Daytime Sedation and Cognition in Healthy Volunteers Taking Gralise, Neurontin or Lyrica
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin|DRUG: Pregabalin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: OTHER
Clinical trial: Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial
Status: COMPLETED
Conditions: Sickle Cell Disease|Asthma|Acute Chest Syndrome
Interventions: DRUG: Budesonide inhalation suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Folic Acid Supplementation in Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Anemia, Sickle Cell
Interventions: DIETARY_SUPPLEMENT: Folic Acid Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Status: UNKNOWN
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DEVICE: Satera GSN Ablation|DEVICE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identifying Predictors of Response to Antipsychotics Using a Treatment Algorithm
Status: UNKNOWN
Conditions: Schizophrenia or Schizoaffective Disorder
Interventions: DRUG: Antipsychotics|DRUG: Antipsychotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Psoralen Ultraviolet Light A Versus Narrow Band Ultraviolet Light B Treatment for Recalcitrant Dermatoses of the Hand
Status: UNKNOWN
Conditions: Vitiligo
Interventions: DEVICE: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Unsutured Versus Sutured Closure of Rectal Defects After Rectal Lesion Excisions Using Transanal Endoscopic Microsurgery
Status: COMPLETED
Conditions: Post-operative Pain|Complications
Interventions: PROCEDURE: Defect Unsutured|PROCEDURE: Defect Sutured
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulligan Bent Leg Raise With and Without Bowen Therapy on Hamstring Tightness in Asymptomatic Adults
Status: RECRUITING
Conditions: Asymptomatic Condition
Interventions: OTHER: Mulligan bent leg raise|OTHER: Mulligan bent leg raise with Bowen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Conventional Landmark, Ultrasound-Assisted, and Real-Time Ultrasound-Guided Techniques in Spinal Anesthesia for Obese Patients
Status: NOT_YET_RECRUITING
Conditions: Spinal Anesthesia|Ultrasound
Interventions: PROCEDURE: Conventional Landmark Technique|PROCEDURE: Ultrasound Assisted Technique|PROCEDURE: Real-Time Ultrasound Guided Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Auditory and Motor Cognitive Distractions on the Neural Provocation Test in Subjects With Neck Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: median nerve mobilization|BEHAVIORAL: Neural stress provocation with cognitive auditory distraction|BEHAVIORAL: Providing neural stress with a motor distraction|BEHAVIORAL: Neural stress provocation with auditory and motor cognitive distraction.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study About Improvement of Chronic Fatigue After Taking Red Ginseng
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome
Interventions: DIETARY_SUPPLEMENT: red ginseng powder capsule|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Association Between Anesthetic Drugs for General Anesthesia and Postoperative Intelligence/Behavioral Assessment Results in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Anesthesia and Neurotoxicity
Interventions: DRUG: dexmedetomidine|DRUG: remifentanil|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bilateral Ultrasound-Guided Erector Spinae Plane Block For Postoperative Analgesia in Breast Reduction Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Breast Hypertrophy
Interventions: PROCEDURE: Erector spinae plane block|OTHER: sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Psychology Program for Chronic Pain After Surgery
Status: NOT_YET_RECRUITING
Conditions: Post-surgical Pain|Pain, Acute|Pain, Chronic|Post-Surgical Pain, Chronic
Interventions: DEVICE: Self-Guided Online ACT Program|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MDMA-assisted Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder
Status: NOT_YET_RECRUITING
Conditions: PTSD
Interventions: DRUG: MDMA|BEHAVIORAL: Cognitive Processing Therapy|BEHAVIORAL: MDMA-assisted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Scoring Drug-coated Balloon in the Treatment of Hemodialysis Arteriovenous Fistula Stenosis
Status: NOT_YET_RECRUITING
Conditions: Arteriovenous Fistula Stenosis
Interventions: DEVICE: Dissolve AV Peripheral Scoring Drug-coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: Glimepiride|DRUG: metformin hydrochloride|DRUG: pioglitazone hydrochloride|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin in Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|Cough
Interventions: DRUG: azithromycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg Furosemide
Status: COMPLETED
Conditions: Body Weight Changes
Interventions: DRUG: CHF Patients: ER Torsemide 40 mg|DRUG: CHF Patients: Furosemide 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis|Secondary Progressive Multiple Sclerosis|Progressive Relapsing Multiple Sclerosis
Interventions: DRUG: Tolebrutinib|DRUG: Placebo|DRUG: Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Status: RECRUITING
Conditions: Tricuspid Regurgitation|Tricuspid Valve Insufficiency|Tricuspid Valve Disease
Interventions: DEVICE: Edwards PASCAL System|DRUG: Optimal Medical Therapy|DEVICE: Edwards PASCAL System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: 0.32% Sodium Fluoride Dentifrice Toothpaste|DRUG: 1.5% Arginine Dentifrice|DRUG: 8.0% Arginine Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Complicated Grief Among Children After a Death From Cancer or Another Cause: A Longitudinal and Prospective Study (CAPS)
Status: COMPLETED
Conditions: Grief
Interventions: BEHAVIORAL: Scales, questionnaires and inventory
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Investigate the Food Effect and Oral Bioavailability of Tablet Formulations Relative to Suspension Formulation of JNJ-54416076 in Healthy Participants
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: JNJ-54416076 (Oral Suspension)|DRUG: JNJ-54416076 (Formulation 1: Direct Compression Tablets)|DRUG: JNJ-54416076 (Formulation 2: Fluid Bed Granulation Tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib and Docetaxel or Pemetrexed in Treating Patients With Advanced Recurrent Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: celecoxib|DRUG: Docetaxel|DRUG: pemetrexed disodium|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Failure|Perimenopausal Disorder|Hormone Disturbance
Interventions: PROCEDURE: lipoaspiration harvest tSVF|PROCEDURE: Platelet Rich Plasma|PROCEDURE: Endovaginal Ultrasound|DEVICE: Cellular Isolation cSVF|DRUG: Normal Saline (NS) .9% 10 mL Injection|DEVICE: emulsification tSVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Heart Healthy Diet for People With High Cardiovascular Risk in China (DECIDE-Diet)
Status: TERMINATED
Conditions: Cardiovascular Disease|Diet Modification|Randomized Controlled Trial
Interventions: OTHER: CHH-diet|OTHER: local usual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myo-inositol, Alpha-Lactalbumin and Folic Acid Treatment in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: myo-inositol, alpha-lactalbumin, folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oxaliplatin, Calcium Folinate, and 5-Fluorouracil as Neoadjuvant Chemotherapy for Resectable Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms|Gastric Cancer
Interventions: DRUG: mFOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Patient and Healthcare Provider: Response to Acupuncture in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Placebo acupuncture|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MANDARIN (S6371)
Status: ACTIVE_NOT_RECRUITING
Conditions: Inoperable Hepatocellular Carcinoma
Interventions: COMBINATION_PRODUCT: TheraSphere™ Yttrium-90 Glass Microspheres|PROCEDURE: conventional Transarterial Chemoembolization(cTACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Pharmacokinetics, and Efficacy of APD371 in Participants With Crohn's Disease Experiencing Abdominal Pain
Status: COMPLETED
Conditions: Crohn's Disease|Abdominal Pain
Interventions: DRUG: Olorinab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Sanfujiu on Patients With Persistent Allergic Rhinitis: Randomized Controlled Study
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Sanfujiu|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib and Belatacept for Desensitization
Status: RECRUITING
Conditions: Highly Sensitized Prospective Kidney Transplant Recipients
Interventions: BIOLOGICAL: carfilzomib|BIOLOGICAL: belatacept|PROCEDURE: Bone marrow aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dermoneuromodulation Techniques in Patients With Non-specific Chronic Neck Pain: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Cervical Pain|Cervical
Interventions: OTHER: Supervised Exercise Program|OTHER: Supervised Exercise Program plus Dermoneuromodulation Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis|Portal Hypertension|Hepatic Decompensation|Surgery
Interventions: PROCEDURE: Autologous bone marrow stem cells infusion （ABMSCi） plus abdominal portal hypertension surgery|PROCEDURE: open abdominal portal hypertension surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can we Forget? Directed Forgetting and Embodied Cognition in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Memorization of the verbs by miming the action|OTHER: Memorization of the verbs by imagining the action|OTHER: Memorization of the action verbs by means of another word|OTHER: Simple memorization of the verbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Fallopian Tube Carcinosarcoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|High Grade Fallopian Tube Serous Adenocarcinoma|High Grade Ovarian Serous Adenocarcinoma|Ovarian Carcinosarcoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Primary Peritoneal Serous Adenocarcinoma|Recurrent Endometrial Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Entinostat|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
Status: COMPLETED
Conditions: Analgesia|Pain Management|Acute Pain
Interventions: PROCEDURE: SIFIB (suprainguinal fascia iliaca block)|OTHER: IPACK (Interspace between the popliteal artery and capsule of the posterior knee )|DEVICE: Patient controlled anagesia device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Safety and Explore Efficacy of SMUP-IA-01 in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: SMUP-IA-01(low-dose)|BIOLOGICAL: SMUP-IA-01(mid-dose)|BIOLOGICAL: SMUP-IA-01(high-dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI/TRUS Fusion Guided Prostate Biopsy- An Improved Way to Detect and Quantify Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: Core Needle TRUS Needle biopsy (Transrectal ultrasound)|PROCEDURE: Core Needle MRI/US image fusion guided needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Efficacy and Safety of Ferric Carboxymaltose (FCM) in Patients With Iron Deficiency Anemia and Impaired Renal Function
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Impaired Renal Function
Interventions: DRUG: Ferric Carboxymaltose (FCM)|DRUG: Iron Sucrose (Venofer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Preemptive Treatment With Oral Valganciclovir Compared With Intravenous (IV) Ganciclovir for Cytomegalovirus Infection After Bone Marrow or Peripheral Blood Stem Cell Transplant
Status: TERMINATED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Valganciclovir|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Transfemoral Prosthetic Socket System
Status: UNKNOWN
Conditions: Lower Limb Amputation
Interventions: DEVICE: Conventional Prosthetic Transfemoral Socket System|DEVICE: Novel Prosthetic transfemoral socket system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.
Status: RECRUITING
Conditions: Colorectal Cancer|Wound Infection|Hernia Incisional
Interventions: COMBINATION_PRODUCT: Polyvinylidene fluoride mesh|COMBINATION_PRODUCT: Prophylactic polypropylene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgical Techniques in Arthroplasty of the Knee (STArK) 1 Trial
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Periarticular infiltration|PROCEDURE: Intra-articular infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Measurement of Pupillary Reactivity by an Automated Pupillometer Determine the Effectiveness of Local Anesthesia Under General Anesthesia?
Status: COMPLETED
Conditions: Knee Surgery|Arthroplasty
Interventions: DEVICE: AlgiScan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: SCRIPPS V: Intracoronary Brachytherapy for Recurrent Restenosis After Multiple Drug-Eluting Stents
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Restenosis
Interventions: RADIATION: Intracoronary brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Virtual Reality Training on Unilateral Spatial Neglect After Stroke
Status: UNKNOWN
Conditions: Stroke|Neglect
Interventions: DEVICE: VR neglect training|DEVICE: VR control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Feasibility and Efficacy of the CollaRx® Bupivacaine Implant Laparoscopic Inguinal or Umbilical Herniorrhaphy
Status: COMPLETED
Conditions: Hernia|Postoperative Pain
Interventions: DRUG: 5x5cm bupivacaine collagen sponges
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Of Drug-eluting Stent Versus Excimer Laser Ablation Combined Drug-coated Balloon To Treat Arteriosclerosis Occlusive Disease Of Lower Extremity
Status: WITHDRAWN
Conditions: Atherosclerosis|Ischemia
Interventions: DEVICE: Drug-eluting Stent|DEVICE: Excimer Laser Ablation Combined Drug-coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 (Crinecerfont) in Pediatric Participants With Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: CAH - Congenital Adrenal Hyperplasia
Interventions: DRUG: Crinecerfont
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial: High Power Short Duration Versus Ablation Index
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal|Catheter Ablation
Interventions: OTHER: Pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Associated With Mindfulness in Chronic Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Comparison of Toric Contact Lenses Fit Characteristics
Status: WITHDRAWN
Conditions: Astigmatism|Refractive Errors
Interventions: DEVICE: Delefilcon A toric soft contact lens|DEVICE: Lehfilcon A toric soft contact lens|DEVICE: Lotrafilcon B toric soft contact lens|DEVICE: Verofilcon A toric soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Sodium-glucose Linked Transporter 2 (SGLT2) and Its Inhibitor Over CARdiotoxicity Induced by Anthracyclines and Breast Cancer Tumorigenesis SCARA-B
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Anthracycline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aerobic Versus Resistive Training on Functional Capacity in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia in Remission
Interventions: OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Immunogenicity, Reactogenicity & Safety of 2 Formulations of GSK's HRV Vaccine as 2-dose Vaccination (Infants)
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Lyophilized formulation of HRV vaccine|BIOLOGICAL: Liquid formulation of HRV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: COVID-19 Vaccination and Breakthrough Infections Among Persons With Immunocompromising Conditions in the United States
Status: COMPLETED
Conditions: Immunocompromised|Immunosuppressed|Covid-19|SARS-COV-2|SARS-COV-2 Infection|Breakthrough Infection
Interventions: BIOLOGICAL: BNT162b2 (Tozinameran)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Plane Block vs Transforaminal Epidural Injection
Status: UNKNOWN
Conditions: Discogenic Low Back Pain
Interventions: DRUG: Bupivacaine;Dexamethasone Solution for Injection|DEVICE: Fluoroscopy|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimizing tDCS Protocol for Clinical Use in Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder|Cognitive Impairment|Psychiatric Disorder
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|DEVICE: multichannel transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT