pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between the Fastrach and CTrach Laryngeal Mask Airway
Status: TERMINATED
Conditions: Intubation
Interventions: DEVICE: Fastrach Laryngeal Mask|DEVICE: CTrach Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: QOL Outcomes in CRS With Polyps
Status: TERMINATED
Conditions: Chronic Rhinosinusitis, Polyps
Interventions: OTHER: Medical optimization and education|PROCEDURE: Standard of Care sinus surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Erigo®Pro Therapy and Motor Imagery on the Balance of Stroke Patients.
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Conventional rehabilitation, the Erigo®Pro table, motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Small Bite Technique Versus Standardised Large Bites Technique in Closure of Midline Laparotomies.
Status: UNKNOWN
Conditions: Incision, Surgical|Suture, Complication|Incisional Hernia
Interventions: PROCEDURE: Small bite suturing Technique|PROCEDURE: Standardised Large Bites Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regain Rate According to gj Anastomosis Size in Gastric Bypass
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid|Anastomosis|Roux-en-y Anastomosis Site
Interventions: PROCEDURE: upper gi endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Graft Versus Host Disease
Interventions: DRUG: Cannabidiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs
Status: COMPLETED
Conditions: Epilepsy With Simple or Complex Partial Onset Seizures
Interventions: DRUG: Eslicarbazepine acetate|DRUG: Eslicarbazepine acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Articaine Versus Lidocaine Buccal Infiltration
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain
Interventions: DRUG: articaine local anethesia with vasoconstrictor|DRUG: lidocaine local anethesia with vasoconstrictor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomic Study to Predict Antidepressant Responsiveness in Depressed Patients
Status: UNKNOWN
Conditions: Depression|Adverse Reaction to Drug
Interventions: DRUG: SSRI treated group|DRUG: non-SSRI treated group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Tac(90 Y-HAT) to Treat Hodgkin's Disease, Non-Hodgkin's Lymphoma and Lymphoid Leukemia
Status: COMPLETED
Conditions: Hodgkin's Disease|Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Y-90 Humanized Anti-Tac|DRUG: Calcium-DTPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-Guided Infraclavicular Block and Ultrasound-Guided Axillary Block
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Ultrasound-guided infraclavicular block|PROCEDURE: Ultrasound-guided axillary block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment
Status: COMPLETED
Conditions: Cerebrospinal Fluid Leaks
Interventions: DRUG: TISSEEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Healthy Volunteers
Interventions: DRUG: Suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: MDMA for Co-occurring PTSD and OUD After Childbirth
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Opioid Use Disorder
Interventions: DRUG: MDMA Assisted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome
Status: COMPLETED
Conditions: Cancer|Skin Fibroblasts|Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside (NR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Type I Collagen for Relieving Scleroderma
Status: COMPLETED
Conditions: Scleroderma|Connective Tissue Diseases
Interventions: DRUG: Oral bovine type I collagen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-discharge Malaria Chemoprevention(PMC) Study
Status: COMPLETED
Conditions: Malaria|Severe Anemia
Interventions: DRUG: dihydroartemisinin-piperaquine|DRUG: dihydroartemisinin-piperaquine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Pre-cooling in Adolescent Tennis Athletes
Status: COMPLETED
Conditions: Risk of Heat Stress
Interventions: BEHAVIORAL: Thermal stress and performance using a pre-cooling protocol|BIOLOGICAL: Thermal stress and performance without a pre-cooling protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: SAGE-324|DRUG: SAGE-324 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Effects of SLx-4090 After Dosing for 14 Days in Subjects With High Triglycerides
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: SLx-4090|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Docetaxel and Irinotecan (DI) for Recurrent or Refractory Bone and Soft Tissue Sarcomas.
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Docetaxel (Taxotere)|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: BMS-708163|DRUG: BMS-708163 + Ketoconazole|DRUG: Ketoconazole|DRUG: Fluconazole|DRUG: BMS-708163 + Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharynx Analgesia Before Upper Gastrointestinal Endoscopy
Status: RECRUITING
Conditions: Upper Gastrointestinal Endoscopy
Interventions: DRUG: Strepsils Intensiv plus Xilocaine spray Arm|DRUG: Xilocaine Spray Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Deep Brain Stimulation of the Nucleus Accumbens as a Novel Treatment in Severe Opioid Addiction
Status: UNKNOWN
Conditions: Addiction
Interventions: OTHER: Deep brain stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of CART22-65s and huCART19 for B-ALL
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia|B Lineage Lymphoblastic Lymphoma
Interventions: BIOLOGICAL: Autologous, humanized anti-CD22 CAR T cell therapy (CART22-65s)|BIOLOGICAL: Autologous, humanized anti-CD19 CAR T cell therapy (huCART19)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Generation Healthy Kids: A Cluster-randomized Trial of a Multi-component, Multi-setting Intervention
Status: RECRUITING
Conditions: Childhood Obesity|Well-Being, Psychological|Physical Inactivity|Sleep|Screen Time|Diet Habit
Interventions: BEHAVIORAL: Food and Nutrition|BEHAVIORAL: Physical Activity (FitFirst)|BEHAVIORAL: Sleep and screen media|BEHAVIORAL: Community capacity building
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Status: RECRUITING
Conditions: Speckle Tracking|Fetus Fetus|Neonate|Structural Heart Disease|Fetal Growth Restriction
Interventions: OTHER: Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Integrating Palliative Care Into Self-Management of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Self-Management Group|BEHAVIORAL: Symptom Management Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Disease|Intestinal Disease|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: probiotics containing Bifidobacterium infantis and Lactobacillus|DIETARY_SUPPLEMENT: placebos containing lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Student Outcomes of Integrative Mental Health Services
Status: COMPLETED
Conditions: Anxiety|Depression|Trauma|Behavior Problems
Interventions: BEHAVIORAL: Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems|OTHER: Monitoring and Feedback System|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Is Instrumentation Necessary for "Static" Degenerative Spondylolisthesis"
Status: WITHDRAWN
Conditions: Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: PROCEDURE: instrumented spinal fusion with laminectomy|PROCEDURE: non-instrumented spinal fusion with laminectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synergism of Immunomodulation and Tumor Ablation
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Durvalumab (MEDI4736)|DRUG: Tremelimumab|RADIATION: Sterotactic body radiation therapy (SBRT)|OTHER: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Pharmacokinetics, Safety and Tolerability of Multiple Doses of CAT-354 in Subjects With Moderate Asthma
Status: TERMINATED
Conditions: Moderate Asthma
Interventions: BIOLOGICAL: CAT-354 1mg/kg|BIOLOGICAL: CAT-354 5 mg/kg|BIOLOGICAL: CAT-354 10mg/kg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REP 2139-Ca / Pegasys™ Combination Therapy in Hepatitis B / Hepatitis D Co-infection
Status: COMPLETED
Conditions: Chronic HBV Infection (HBeAg Negative)
Interventions: DRUG: REP 2139-Ca + Pegasys (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Manual Therapy Plus Pain Neuroscience Education With Integrated Motivational Interviewing in Individuals With Non-Specific Chronic Low Back Pain
Status: COMPLETED
Conditions: Non-specific Chronic Low Back Pain
Interventions: OTHER: MT+ PNE with MI|OTHER: MT|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tracheal Suctioning With or Without Expiratory Pause Maneuver in Children
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Pediatric Respiratory Diseases
Interventions: OTHER: Endotracheal suctioning with expiratory pause|OTHER: Endotracheal suctioning without expiratory pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D Supplementation for Treatment of Dyslipidemia
Status: UNKNOWN
Conditions: Dyslipidemias
Interventions: DRUG: Vitamin D3 (Treatment)|OTHER: Mixed diet of carbohydrate and protein (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of and Immune Response to a Human Parainfluenza Virus Type 3 Ebola Virus Vaccine (HPIV3-EbovZ GP) in Healthy Adults
Status: COMPLETED
Conditions: Hemorrhagic Fever, Ebola
Interventions: BIOLOGICAL: HPIV3-EbovZ GP Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health
Status: RECRUITING
Conditions: Pregnancy Related|Substance Use|Mental Health Issue
Interventions: BEHAVIORAL: NEXUS intervention|BEHAVIORAL: Standardized Non-Medical fetal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms
Status: UNKNOWN
Conditions: Aneurysm
Interventions: DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: KSX01-TCRT Injection Project in Solid Tumors
Status: RECRUITING
Conditions: TCR-T Cells|Refractory Solid Tumors|Relapsed Solid Tumors
Interventions: DRUG: KSX01-TCRT injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability of Aliskiren (SPP100) in Patients With End Stage Renal Disease on Hemodialysis and Matched Healthy Subjects
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGF
Status: TERMINATED
Conditions: Colorectal Cancer|Colorectal Adenocarcinoma
Interventions: DRUG: Brivanib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pregabalin in Patients With Radicular Pain
Status: COMPLETED
Conditions: Neuropathy; Radicular, Lumbar, Lumbosacral|Failed Back Surgery Syndrome|Spinal Stenosis|Herniated Disc
Interventions: DRUG: Pregabalin|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Disulfiram in Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioma|Glioblastoma
Interventions: DRUG: Disulfiram|DIETARY_SUPPLEMENT: Copper|DRUG: Alkylating Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Beetroot Juice Intake on Performance and Physiological Parameters
Status: COMPLETED
Conditions: Pulmonary Function|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Beetroot juice ingestion|DIETARY_SUPPLEMENT: Placebo ingestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effectiveness of Structured Education According to Premenstrual Syndrome Symptom Map
Status: COMPLETED
Conditions: Premenstrual Syndromes|Education|Menstrual Cycle Disorder
Interventions: BEHAVIORAL: Structured training according to premenstrual syndrome symptom map
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Determine the Effects Treatment With Amlexanox 0.5% Oral Rinse Solution on Oral Mucositis Associated With Radiation Therapy for Cancer of the Head and Neck Region
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: amlexanox|DRUG: Vehicle rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Full Length Versus Proximal Renal Arteries Ablation
Status: COMPLETED
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: DEVICE: Thermocool®Rcatheter|DEVICE: Thermocool®Rcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rebastinib Plus Antitubulin Therapy With Paclitaxel or Eribulin in Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Breast Adenocarcinoma|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast|Recurrent Breast Carcinoma|Stage IV Breast Cancer
Interventions: DRUG: Rebastinib|DRUG: Paclitaxel|DRUG: Eribulin Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vertebral Bone Marrow Clot for Spinal Surgery
Status: RECRUITING
Conditions: Degenerative Spine Diseases
Interventions: BIOLOGICAL: Vertebral bone marrow (vBMA) clot|OTHER: Bone allograft chips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Placebo to omarigliptin|DRUG: Glipizide|DRUG: Placebo to glipizide|BIOLOGICAL: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage
Status: COMPLETED
Conditions: Cervical Incompetence
Interventions: DRUG: Chloroprocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Therapeutic Intervention Through Selective Functional Movement Assessment on Pain, Function, Balance and Gait in Patients With Chronic Nonspecific Neck Pain
Status: RECRUITING
Conditions: Chronic Nonspecific Neck Pain
Interventions: BEHAVIORAL: Personalized exercise|BEHAVIORAL: Stabilization exercise|BEHAVIORAL: General exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)
Status: RECRUITING
Conditions: Dravet Syndrome
Interventions: DRUG: ETX101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orlistat Reduces Uric Acid in Overweight/Obese Patients With Hyperuricemia
Status: COMPLETED
Conditions: Uric Acid
Interventions: DRUG: Orlistat|DRUG: Orlistat placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of GT201 in Combination With PD-1 Inhibitor for Advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: HNSCC|Adults
Interventions: BIOLOGICAL: GT201 in combination with PD-1 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2484595 in Patients With High LDL-C or Low HDL-C
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: LY2484595|DRUG: Atorvastatin|DRUG: Simvastatin|DRUG: Rosuvastatin|DRUG: Placebo for LY2484595|DRUG: Placebo for Statins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Orelabrutinib in Patients With AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder
Status: UNKNOWN
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Orelabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases
Status: COMPLETED
Conditions: Accelerated Phase of Disease|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL|Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Blastic Phase|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia|Previously Treated Myelodysplastic Syndrome|Primary Myelofibrosis|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Disease|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: DRUG: Belinostat|DRUG: Azacitidine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of SomnaPatch With Polysomnography in Sleep Disordered Breathing
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Central Sleep Apnea|Mixed Sleep Apnea|Cheyne-Stokes Respiration
Interventions: DEVICE: SomnaPatch|DEVICE: Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|B-cell Acute Lymphoblastic Leukemia|High-risk Myelodysplastic Syndrome
Interventions: DRUG: VIP943
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants
Status: RECRUITING
Conditions: Bacterial Infections
Interventions: DRUG: Xeruborbactam Oral Prodrug|DRUG: Ceftibuten|DRUG: Xeruborbactam Oral Prodrug Placebo|DRUG: Ceftibuten Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Preoperative N1539 in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: N1539|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ENPP1 Deficiency
Status: ACTIVE_NOT_RECRUITING
Conditions: Ectonucleotide Pyrophosphatase/phosphodiesterase1 Deficiency|Autosomal Recessive Hypophosphatemic Rickets|Generalized Arterial Calcification of Infancy
Interventions: DRUG: INZ-701
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Pedicle Clamping on Hepatocellular Injury During Liver Surgery
Status: COMPLETED
Conditions: Hepatocellular Injury|Blood Loss
Interventions: PROCEDURE: Pringle manoeuvre 15 minutes|PROCEDURE: Pringle manoeuvre 30 minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical and Mechanistic Study of Transverse Tibial Transport in Complex Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: PROCEDURE: Transverse Tibial Transport (TTT)|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Impact of E-PRF and H-PRF on Healing After Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: Platelet-Rich Fibrin
Interventions: BIOLOGICAL: H-PRF (Horizontal-platelet rich fibrin)|BIOLOGICAL: E-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementing Acupuncture and Chinese Herbal Medicine Into Palliative Care
Status: WITHDRAWN
Conditions: Advanced Cancer|Lung Cancer|Breast Cancer|Colo-rectal Cancer|Pancreas Cancer|Cholangiocarcinoma|Quality of Life|Symptoms and Signs
Interventions: OTHER: Treatment modalities of Traditional Chinese Medicine (Acupuncture, Chinese herbal medicine, Tunia, Chinese dietetics)|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Strength and Aerobic Training in Elderly Lymphoma Patients During Chemotherapy and Its Impact on Treatment Outcomes, Patients Functioning and Biological Markers of Aging
Status: UNKNOWN
Conditions: Strength Aerobic Training Elderly Lymphoma Sarcopenia Aging
Interventions: BEHAVIORAL: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: MEDI4736|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus for Cowden Syndrome With Colon Polyposis
Status: ACTIVE_NOT_RECRUITING
Conditions: PTEN Gene Mutation|PTEN Hamartoma Tumor Syndrome|PTEN Hamartoma Syndrome|Cowden Syndrome|Bannayan Syndrome|Bannayan Zonana Syndrome|Polyposis
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: N-Acetylcysteine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With or Without SBRT in Patients With Stage IV Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Cancer|Stage IV Lung Cancer
Interventions: RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Clinical Decision-making of AI Technology to a Multi-professional Care Team in eCBT for Depression
Status: RECRUITING
Conditions: Depression
Interventions: BEHAVIORAL: e-CBT|BEHAVIORAL: e-CBT + Phone Call|BEHAVIORAL: e-CBT + Phone Call + Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemoradiotherapy and MK-3475 for Esophageal Squamous Cell Carcinoma (ACTS-29)
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: MK-3475(pembrolizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neuromuscular Electrical Stimulation in Geriatric Population
Status: COMPLETED
Conditions: Age-Related Atrophy|Physical Disorder
Interventions: OTHER: 5 minutes stimulation|OTHER: 10 minutes stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Modified Playground Environment on Health, Particularly Immune System
Status: COMPLETED
Conditions: Atopic Disorders|Immune System Diseases
Interventions: OTHER: Biodiversity powder|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap
Status: RECRUITING
Conditions: Perineum; Wound|Postoperative Complications|Rectal Neoplasms|Rectus Abdominis Hernia|Prospective Studies|Wound Heal|Sexual Health
Interventions: PROCEDURE: Reconstruction with robot-assisted rectus abdominis muscle flap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Micafungin Versus Fluconazole for Prevention of Invasive Fungal Disease in Living Donor Liver Transplant Recipients
Status: UNKNOWN
Conditions: Liver Transplant Recipient
Interventions: DRUG: micafungin|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Efficacy and Safety of 3 Different Doses of co.Don Chondrosphere to Treat Large Cartilage Defects
Status: COMPLETED
Conditions: Large Articular Cartilage Lesions of the Femoral|Condyle, Trochlea, Tibia or Retropatellar
Interventions: DRUG: co.don chondrosphere®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Insulin Rinsulin® NPH Compared to Humulin® NPH in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: Insulin Humulin® NPH|BIOLOGICAL: Insulin Rinsulin® NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Angiotensin Converting Enzyme Activity on Exercise Training Sensitivity
Status: COMPLETED
Conditions: Exercise|Angiotensin-Converting Enzyme Inhibitors
Interventions: DRUG: Enalapril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DiSCIoser: Improving Arm Sensorimotor Functions After Spinal Cord Injury Via Brain-Computer Interface Training
Status: RECRUITING
Conditions: Spinal Cord Injuries|Motor Disorders
Interventions: OTHER: EEG-based BCI system for (hands) Motor Imagery training|OTHER: Control - MI intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAC Supplementation and Soccer Specific Performance
Status: COMPLETED
Conditions: Skeletal Muscle Damage|Exercise-induced Aseptic Inflammation|Skeletal Muscle Performance|Antioxidant Status
Interventions: DIETARY_SUPPLEMENT: N-acetylcysteine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of SkinPlus-Hyal® to Nasolabial Fold
Status: COMPLETED
Conditions: Wrinkle
Interventions: DEVICE: SkinPlus-Hyal®|DEVICE: Restylane®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide Plus PD-1 Plus Paclitaxel of Neoadjuvant Treatment in Low HR Expression,HER2-negative Early Breast Cancer.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Chidamide Plus Toripalimab Plus Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Comprehensive Multi-disciplinary Program and Conventional Care Program on Fragility Fracture Elderly
Status: COMPLETED
Conditions: Hip Fracture
Interventions: OTHER: Multi-disciplinary management program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Healthcare Intervention Program on Treatment Adherence in People With Newly Diagnosed Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Treatment Adherence|Quality of Life|Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions: BEHAVIORAL: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Intranasal Midazolam Versus Intravenous Diazepam for Control of Seizures in Children
Status: UNKNOWN
Conditions: Seizures
Interventions: DRUG: IV diazepam|DRUG: I/N Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: MaZiRenWan (MZRW) Low dose|DRUG: MaZiRenWan (MZRW) Median dose|DRUG: MaZiRenWan (MZRW) High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: CART-PSMA-TGFβRDN|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ensifentrine for 24 Weeks in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Ensifentrine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of 032-11 Haemostat in Cardiac and Thoracic Aortic Surgery
Status: UNKNOWN
Conditions: C.Surgical Procedure; Cardiac|Haemorrhage.
Interventions: DEVICE: 032-11|DEVICE: Floseal (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Is To Estimate The Time Course Of Pf-04764793 In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F|DRUG: Treatment G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|Skin Toxicity
Interventions: DRUG: Clindamycin Phosphate|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near-infrared Image Guided Surgery in Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreatic Adenocarcinoma
Interventions: DRUG: Bevacizumab-800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Oral ENMD-2076 Administered to Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Cancer|Peritoneal Cancer
Interventions: DRUG: ENMD-2076
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INO 5401 Vaccination in BRCA1/2 Mutation Carriers
Status: RECRUITING
Conditions: BRCA1/2 Mutation
Interventions: DRUG: INO-5401|DRUG: INO-9012|DEVICE: Cellectra 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Sinufoam-Dexamethasone Mixture on Post Endoscopic Sinus Surgery Outcomes
Status: UNKNOWN
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: Dexamethasone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a New Technique for Imaging Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Tumors That Express CA19-9
Interventions: DRUG: MVT-2163|DRUG: MVT-5873
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Determine Safety and Immunogenicity of the Candidate COVID-19 Vaccine AZD1222 Delivered by Aerosol in Healthy Adult Volunteers
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19|SARS-CoV-2 Infection
Interventions: BIOLOGICAL: 1x10^9 vp AZD1222|BIOLOGICAL: 5x10^9 vp AZD1222|BIOLOGICAL: 1x10^10 vp AZD1222
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Natural Killer (NK) Cell Therapy Targeting CD33 in Acute Myeloid Leukemia
Status: RECRUITING
Conditions: AML, Adult
Interventions: DRUG: QN-023a|DRUG: Cyclophosphamid|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indirect Assessment and Intervention for Perinatal Drug Use
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: WIDUS computer-delivered, indirect brief intervention|BEHAVIORAL: Nutrition time control/placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-use Disorder|Medication Assisted Treatment|Chronic Pain
Interventions: BEHAVIORAL: Psychosocial Pain Management (PPMI)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Coronary Angiography Guided Revascularization in STEMI
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: OTHER: Angiography-guided PCI|OTHER: Angiography-derived FFR PCI indication and planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Study to Investigate the Tolerance and Pharmacokinetics of Finamine Tablets in China
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Finamine tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of a Single Dose of Menactra® Vaccine 4-6 Years After Prior Menactra Vaccine
Status: COMPLETED
Conditions: Meningitis|Meningococcal Infection
Interventions: BIOLOGICAL: Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate: Menactra®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LEAPTogether: An Intergenerational Intervention to Address Loneliness and Social Isolation
Status: RECRUITING
Conditions: Social Isolation|Loneliness|Intergenerational Relations
Interventions: BEHAVIORAL: Intergenerational Virtual Paired Exercise|BEHAVIORAL: Peer Virtual Paired Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multifaceted Nurse-based Strategy Reduces HEart FaiLure Morbidity in PatiENts Admitted for Acute Decompensated Heart Failure in Brazil
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Home based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety of Gabapentin in a Potential Over-the-Counter Population With Occasional Sleeplessness
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the PLAN CUIDARTE on the Caregiving Competence of People With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Caregiver Burden|Discharge Plan|Care Transitions|Nursing
Interventions: OTHER: PLAN CUIDARTE|OTHER: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiomyopathy, Hypertrophic Obstructive
Interventions: DRUG: Mavacamten
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Paclitaxel-eluting Balloon to Paclitaxel-eluting Stent
Status: COMPLETED
Conditions: Coronary Instent Restenosis
Interventions: DEVICE: SeQuent® Please|DEVICE: Taxus Liberte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Endostatin in Advanced Pancreatic Neuroendocrine Tumor
Status: COMPLETED
Conditions: Advanced Well-differentiated Pancreatic Neuroendocrine Tumor
Interventions: DRUG: temozolomide or dacarbazine-based chemotherapy, endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Protein Diet in Preventing the Progression of Chronic Kidney Disease(CKD)---a Prospective Study
Status: UNKNOWN
Conditions: Renal Insufficiency, Chronic
Interventions: BEHAVIORAL: low protein diet plus α-keto acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cold Application on the Hemostasis, Extremity Pain And Terumo Band Usage After Transradial Angiography
Status: NOT_YET_RECRUITING
Conditions: Radial Artery|Pain|Local Application / Packing Too Cold|Hemostasis|Angiography
Interventions: DEVICE: cold application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE