pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Remission of Type 2 Diabetes With Dapagliflozin (READ Trial)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Intensive lifestyle intervention|DRUG: Dapagliflozin 10 MG Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship
Status: COMPLETED
Conditions: Stage 0a Bladder Cancer AJCC v8|Stage 0is Bladder Cancer AJCC v8|Stage I Bladder Cancer AJCC v8
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|BEHAVIORAL: Behavioral Dietary Intervention|OTHER: Educational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of an Adjuvant in Improving Immune Response to Hepatitis B Virus Vaccine in HIV Infected Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Hepatitis B virus vaccine with GM-CSF adjuvant|BIOLOGICAL: Hepatitis B virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study on the Effect of Adding Raltegravir +/- a Second Drug on HIV Levels in the Gut
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: raltegravir|DRUG: Study NNRTI|DRUG: Study PI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis (AD)
Interventions: DRUG: Dupilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor
Status: COMPLETED
Conditions: Hematologic Malignancy
Interventions: DRUG: melphalan|DRUG: fludarabine|DRUG: thiotepa|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Mycophenolate Mofetil|DRUG: Filgrastim|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMPROVE AKI Cluster-Randomized Trial
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: BEHAVIORAL: AKI Prevention Toolkit|BEHAVIORAL: Technical Assistance (TA)|BEHAVIORAL: Virtual Learning Collaborative (VLC)|BEHAVIORAL: Automated Surveillance Reporting (ASR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
Status: RECRUITING
Conditions: Colon Cancer Screening
Interventions: OTHER: FITx3 intervention and CRC education|OTHER: Colorectal Cancer (CRC) education alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploring the Perspectives and Experiences of PrEP-eligible Black Women in Texas in Relation to Readiness for PrEP Uptake and Adherence
Status: COMPLETED
Conditions: PrEP Uptake Perspectives|PrEP Uptake Experiences|PrEP Adherence Perspectives|PrEP Adherence Experiences
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brief Virtual Mindfulness-based Group Intervention With Social Support for Perinatal Individuals
Status: NOT_YET_RECRUITING
Conditions: Substance Use|Pregnancy Related|Mental Health
Interventions: BEHAVIORAL: Virtual Mindfullness-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Non-animal Chondroitin Sulphate for Overweight Subjects With Knee Ostoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Non-Animal Chondroitin Sulphate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OpT2mise Glucose Control in Type 2 Diabetes Mellitus (DM) With Insulin Pump Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Insulin Pump (Medtronic Minimed Paradigm® VEO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma
Status: RECRUITING
Conditions: Follicular Lymphoma (FL)
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: Lenalidomide and rituximab (R2) in 28-day cycles for up to 12 cycles.|DRUG: Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone or prednisolone (R-CHOP) in 21-day cycles for 6 to 8 cycles|DRUG: Lymphodepleting chemotherapy|OTHER: Corticosteroids and/or Radiation (Bridging therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: Carcinoma|Non-Small-Cell Lung Cancer
Interventions: DRUG: INC280
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1
Status: NOT_YET_RECRUITING
Conditions: HIV-1
Interventions: DRUG: PGT121.414.LS|DRUG: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of ET190L1 ARTEMIS™ T Cells in Relapsed and Refractory CD19+ Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphomas Non-Hodgkin's B-Cell
Interventions: BIOLOGICAL: ET190L1 ARTEMIS™ T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HIV Patients With Undetectable Viral Load and Abnormal Lipids Switching to Atazanavir/Ritonavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: atazanavir/ritonavir +2 NRTIs (immediate Switch Group)|DRUG: LPV/r +2 NRTIs (Delayed/optional Switch Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Lignocaine for Topical Airway Anesthesia During Flexible Bronchoscopy: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Bronchopulmonary Disease
Interventions: DRUG: Lignocaine Nebulization|DRUG: Saline Nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Observational Study to Evaluate Quality of Life (QoL) and Influence of Cognitive Status on QoL in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) During 2 Years Treatment With Rebif New Formulation (RNF)
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Pharmacodynamics Study of Pegfilgrastim in Chemotherapy Patients
Status: UNKNOWN
Conditions: Neutropenia
Interventions: DRUG: Pegfilgrastim|DRUG: Pegfilgrastim|DRUG: Pegfilgrastim|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluocinolone Acetonide Implant for Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DEVICE: fluocinolone acetonide (Retisert Implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balloon Sinus Dilation In Office or OR
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DEVICE: FESS instruments with or without balloon treatment|DEVICE: Balloon Sinuplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: VELCADE®-BEAM and Autologous Hematopoietic Stem Cell Transplantation for Non-Hodgkin's Lymphoma, or Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Non-hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Bortezomib|DRUG: BEAM (carmustine (BCNU), etoposide, cytarabine, melphalan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPR Education Via a Mobile Application Compared to VSI Kit
Status: COMPLETED
Conditions: Cardiovascular Risk Factors|Coronary Disease|Cardiac Arrest
Interventions: OTHER: Education: CPR Training via Mobile App|OTHER: Education: CPR Training using the CPR Anytime VSI Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of an Interactive Mental Wellness (I-AM-WELL) Program on Final Year Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Resilience|Practice Readiness|Depression|Anxiety|Stress|Physical Activity|Eating Behavior
Interventions: BEHAVIORAL: I-AM-WELL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients
Status: UNKNOWN
Conditions: Beta-Thalassemia|Bone Marrow Transplantation
Interventions: DRUG: Zoledronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients.
Status: UNKNOWN
Conditions: Initial Radiological Diagnosis Eligible for Tumor Resection|Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type)|Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide
Interventions: DEVICE: SonoCloud-9 (SC9) device|DRUG: Temozolomide according Stupp protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PMCF Study in Patients With Thoracoabdominal Aortic Aneurysms Treated With E-nside TAAA Multibranch Stent Graft System (INNER-B-APAC)
Status: RECRUITING
Conditions: Thoracoabdominal Aortic Aneurysm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: OT Intervention Via Telehealth for Children With ASD and ADHD
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Occupational Therapy via Telehealth|OTHER: Standard of Care Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A PHASE 2B PLACEBO-CONTROLLED, RANDOMIZED STUDY OF A RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE IN PREGNANT WOMEN
Status: COMPLETED
Conditions: Respiratory Tract Infection
Interventions: BIOLOGICAL: RSV vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Training Strategies for Children With Repaired Tetralogy of Fallot
Status: SUSPENDED
Conditions: Tetralogy of Fallot|Congenital Heart Defects|Congenital Abnormalities|Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electronic Health Technology for Assessment of Physical Activity and Eating Habits in Children and Adolescents Who Are Overweight and Those With Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DEVICE: motion detection with a motion sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioavailability Study of DFD-03 Compared to Tazorac® in Patients With Moderate Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene Lotion, 0.1%|DRUG: Tazarotene Cream, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Radiation Therapy Positioning System (RTPS) in Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: Radiation Therapy Positioning System (RTPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cerebellar rTMS for Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: OTHER: Bilateral 1 Hz Cerebellar rTMS|OTHER: Sham (electrical stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Adding Dexamethasone Plus Ketamine to Bupivacine in Serrtatus Plane Block
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Serratus anterior plane block for MRM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: HIV Indicator Diseases in Hospital and Primary Care
Status: UNKNOWN
Conditions: HIV Infections|Primary Health Care|Acquired Immunodeficiency Syndrome|Sexually Transmitted Diseases, Viral|Herpes Zoster|Dermatitis, Seborrheic|Pneumonia|Infectious Mononucleosis|Psoriasis|Candida Infection|Lymphadenopathy|Uterine Cervical Dysplasia|Weight Loss|Diarrhea Chronic|Leukopenia|Thrombocytopenia|AIDS Defining Illness|HIV Indicator Condition
Interventions: BEHAVIORAL: Peer to peer feedback|DIAGNOSTIC_TEST: HIV rapid test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long Term Outcome on Brain and Lung of Different Oxygen Strategies in ARDS Patients
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Modulation of Inspired Fraction of Oxygen (FiO2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Levothyroxine Dosing in Infants With Congenital Hypothyroidism
Status: COMPLETED
Conditions: Congenital Hypothyroidism
Interventions: DRUG: Levothyroxine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis
Status: RECRUITING
Conditions: Periprosthetic Fracture of the Upper or Lower Limb|Peri-implant Fracture of the Upper or Lower Limb|Periprosthetic Fractures|Peri-implant Fracture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness
Status: RECRUITING
Conditions: Glioblastoma|Glioma|Glioma Glioblastoma Multiforme
Interventions: OTHER: cell isolation from tumor biopsies and biomarker investigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function
Status: COMPLETED
Conditions: Body Image|Urinary Incontinence|Anal Incontinence|Anorectal Disorder|Constipation|Pelvic Organ Prolapse|Sexual Dysfunction|Pregnancy Related|Postpartum Disorder
Interventions: DIAGNOSTIC_TEST: questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Doxorubicin Transdrug Study in Patients Suffering From Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Doxorubicin 20 mg/m2|DRUG: Doxorubicin 30 mg/m2|DRUG: Best Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S-1, Cisplatin-based Chemoradiotherapy, Induction Chemotherapy, Locally Advanced Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Induction DCS chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
Status: COMPLETED
Conditions: Parenting Capacities of Substance Abusing Mothers
Interventions: BEHAVIORAL: Mothers and Toddlers Program|BEHAVIORAL: Parent Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon(Peg-IFN) in Reducing Relapse Rate in Patients After Discontinuation of NUC Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: PegIFN alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Polyglucoferron Compared to i.v. Ferric Carboxymaltose and Oral Iron Substitution in Preoperative Treatment of Iron Deficiency Anaemia in Patients
Status: WITHDRAWN
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Polyglucoferron|DRUG: Ferric carboxymaltose|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
Status: TERMINATED
Conditions: Pain, Postoperative
Interventions: DRUG: ITM + Sham QLB|DRUG: ITM + Bupivacaine QLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Virtual Environments For Supporting Obesity Treatment
Status: UNKNOWN
Conditions: Obesity|Morbid Obesity
Interventions: BEHAVIORAL: Experiential-Cognitive Therapy for Obesity|BEHAVIORAL: Behavioral cognitive Treatment|DIETARY_SUPPLEMENT: Nutritional groups (NT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High-Flow Nasal Oxygenation Versus Standard Oxygenation in Gastrointestinal Endoscopy With Sedation.
Status: COMPLETED
Conditions: Gastrointestinal Endoscopy|Sedation
Interventions: DEVICE: High-flow nasal cannula oxygenation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Relapsed/Refractory Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myopia-control Efficacy by Peripheral Defocus Lens (PDL)
Status: UNKNOWN
Conditions: Myopia, Progressive
Interventions: DEVICE: Single vision lens|DEVICE: +2D PDL|DEVICE: +3D PDL|DEVICE: +4D PDL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Umbilical Cord Derived Wharton's Jelly for Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Umbilical Cord-derived Wharton's Jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achievement of Better Examinee Compliance on Colon Cleansing Using Commercialized Low-Residue Diet
Status: UNKNOWN
Conditions: Colonoscopy|Colon Cleansing|Low-Reside Diet
Interventions: OTHER: Low-residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Chromium Supplementation on Parameters of the Metabolic Syndrome in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Baker's yeast (Bio Chromium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Whole Body Vibration in Chronic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: High frequency whole body vibration|PROCEDURE: Low frequency whole body vibration|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REal-worLd vAlidaTION of PhotoPlehtysmoGraphy (for Atrial Fibrillation Detection)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Heart rhythm measurements with FibriCheck®|DIAGNOSTIC_TEST: Heart rhythm measurements with Kardia Mobile®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis
Status: COMPLETED
Conditions: Aspergillosis|Invasive Fungal Infection
Interventions: DRUG: Isavuconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 500 "Normal" Adult Subjects Who Have Experienced no Known Brain Injury Will Participate in Collecting Data That Will Assist With the Optimization of the Diagnostic Capabilities of the Harmony in Detecting Neurologic Abnormalities.
Status: NOT_YET_RECRUITING
Conditions: Cranial Waveform in Normal Patients as a Result of Cardiac Cycle|Healthy
Interventions: DEVICE: Harmony Headset
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FAZA PET IMAGING IN DETECTING LYMPH NODE METASTASES IN RENAL CELL CARCINOMA PATIENTS
Status: COMPLETED
Conditions: Renal Cell Carcinoma (RCC)
Interventions: OTHER: 18F-FAZA PET IMAGING TECHNIQUE IN DETECTING LYMPH NODE METASTASES IN RENAL CELL CARCINOMA PATIENTS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Endogenous and Exogenous Ketosis in Patients With Non-ischemic Chronic Heart Failure With Reduced Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction|Ketosis
Interventions: BEHAVIORAL: Ketogenic diet|DIETARY_SUPPLEMENT: Exogenous ketones|BEHAVIORAL: Standard diet + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: AT-101|DRUG: topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction of Stable Chimerism for Sickle Cell Anemia
Status: COMPLETED
Conditions: Blood Disease|Hematopoietic Stem Cell Transplantation|Anemia, Sickle Cell
Interventions: PROCEDURE: Hematopoietic Stem Cell Transplantation|DRUG: Immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESOLVE: Abemaciclib + Letrozole +/- Metformin or Zotatifin in Endometrial or Low-Grade Serous Ovarian Cancer
Status: RECRUITING
Conditions: Endometrial Cancer|Ovarian Cancer
Interventions: DRUG: Letrozole|DRUG: Abemaciclib|DRUG: LY3023414|DRUG: Metformin|DRUG: Zotatifin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Imaging Characteristics OCT of Skin Lesions Requiring Biopsy / Resection
Status: WITHDRAWN
Conditions: Mixed Tumor, Malignant|Biopsy|Resection|Carcinoma|Keratosis
Interventions: DEVICE: Optical Coherence Tomography (OCT) with Vivosight|DEVICE: Optical Coherence Tomography (OCT) with Skintell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarker Guided Treatment in DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: chidamide|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ 61393215 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-61393215|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Combination Therapy of Low Doses of rFVIIa and FEIBA for Severe Hemophilia A Patients With an Inhibitor to Factor VIII
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: rFVIIa-FEIBA therapy for hemophilia A inhibitors|DRUG: FEIBA- Activated Prothrombin Complexes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients
Status: RECRUITING
Conditions: Metabolic Acidosis|Kidney Transplant; Complications|Vascular Diseases
Interventions: DRUG: Sodium bicarbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: 400 mg LX4211|DRUG: 1000 mg metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Alcohol Use on Chronic Orofacial Pain
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: DRUG: Ethanol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect and Mechanism of Electroacupuncture on Acute Chemotherapy-induced Nausea and Vomiting
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: DEVICE: acupuncture (Huatuo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of PRP With Er-YAG Laser Versus With Microneedling in Localized Stable Vitiligo
Status: UNKNOWN
Conditions: Localized Vitiligo
Interventions: DEVICE: fractional Erbium-YAG laser|DEVICE: microneedling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Relevance of High-Intensity Functional Training in Patients With First-Episode Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizotypal Disorder|First Episode Psychosis|Psychotic Disorders|Schizoaffective Disorder
Interventions: OTHER: The COPUS intervention|OTHER: Usual Care (OPUS treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial for Quantity-Effect Relationship of Acupuncture With Two-ways Regulation to Treat Functional Enteropathy
Status: UNKNOWN
Conditions: Functional Constipation|Functional Diarrhea
Interventions: DRUG: Mosapride Citrate tablet|DEVICE: Low-dose acupuncture|DEVICE: High-dose acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single or Repeat Dose of G03-52-01 in Adult Subjects
Status: RECRUITING
Conditions: Healthy|Botulinum Toxin
Interventions: DRUG: G03-52-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Biodegradable Stent Placement to Reduce Complications After Pancreatoduodenectomy
Status: RECRUITING
Conditions: Fistula Pancreatic
Interventions: PROCEDURE: Fast Degradable, Biodegradable ARCHEMEDES stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating The Efficacy Of Varenicline In Cessation Of Oral Smokeless Tobacco Use
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: DRUG: Varenicline Tartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PowerAssert Radio-Frequency (RF) Guidewire Coronary In-Stent Chronic Total Occlusion (CTO)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PowerAssert RF wire in crossing coronary in-stent chronic total occlusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular (Wet) AMD
Interventions: DRUG: AVT06 (proposed aflibercept biosimilar)|DRUG: Eylea® (Aflibercept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Different Exercise Programs in Patients With Restless Legs Syndrome.
Status: COMPLETED
Conditions: Restless Legs Syndrome|Anxiety|Sleep
Interventions: OTHER: Aerobic exercise|OTHER: Stretchin exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ING200336, Pharmacokinetic and Safety Study in Pregnant Women With Human Immuno Virus Infection
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections|Arthralgia
Interventions: DRUG: DTG 50 mg /ABC 600 mg /3TC 300 mg FDC tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|PROCEDURE: Leukapheresis|BIOLOGICAL: Cytokine-induced killer cells|BIOLOGICAL: IL-2|DRUG: ALT-803|PROCEDURE: Peripheral blood for correlative studies|PROCEDURE: Bone marrow for correlative studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Feedback in Colonoscopy
Status: UNKNOWN
Conditions: Colorectal Cancer|Healthy
Interventions: DEVICE: Colonoscopy Progression Score (CoPS)|DEVICE: Colonoscopy Retraction Score (CoRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin in Obese Children and Adolescents
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Metformin|BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Conventional and Robot-assisted(Da Vinci®)Laparoscopic Interventions for Hysterectomy
Status: COMPLETED
Conditions: Laparoscopic Technique no Switch to Open|Duration of Surgery|Intraoperative Complications|Postoperative Complications
Interventions: PROCEDURE: Conventional Laparoscopic Hysterectomy|PROCEDURE: Robot-assisted (Da Vinci®) laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery
Status: RECRUITING
Conditions: Stroke|Atrial Fibrillation
Interventions: DRUG: Non-vitamin K oral anticoagulant (NOAC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome
Status: COMPLETED
Conditions: Cushing's Syndrome|Ectopic Corticotropin Syndrome|Adrenal Adenoma|Adrenal Carcinoma|AIMAH|PPNAD
Interventions: DRUG: Osilodrostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED2PrEP - Patient Focused, Low-burden Strategies for PrEP Uptake Among Emergency Departments
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: PVO|BEHAVIORAL: TSH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Lactose Intolerant
Interventions: OTHER: low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Taxotere (Docetaxel) New Indication: Squamous Cell Carcinoma of the Head and Neck (SCCHN) Treatment Registration Trial
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: DOCETAXEL|DRUG: CISPLATIN|DRUG: 5-FLUOROURACIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma
Status: WITHDRAWN
Conditions: Anxiety|Stage IV Melanoma
Interventions: DRUG: psilocybin|DRUG: psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femtosecond Laser Assisted Cataract Surgery in The NHS
Status: COMPLETED
Conditions: Cataract|Surgery
Interventions: PROCEDURE: Conventional cataract surgery (phacoemulsification)|PROCEDURE: Femtosecond laser assisted cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability of Human Papillomavirus (HPV) Self-sampling Tools for Cervical Cancer Prevention
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: HPV self-sampling kit|BEHAVIORAL: Culturally-targeted Fear Appeal Message|BEHAVIORAL: Fear Appeal Message|BEHAVIORAL: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Combination of Basiliximab and Pegaspargase in the Treatment of ENKTCL
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: DRUG: Basiliximab|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information-Motivation-Behavioral Skills Model-based Intervention to Domiciliary Non-invasive Ventilation of Patients
Status: RECRUITING
Conditions: Hypercapnic Respiratory Failure|Noninvasive Ventilation
Interventions: OTHER: Information-Motivation-Behavioral skills (IMB) model-based intervention|OTHER: Control - usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Comparison of Revolve™ and AuraGen 123 With AuraClens™ in Autologous Fat Grafting to the Breast
Status: TERMINATED
Conditions: Autologous Fat Grafting
Interventions: DEVICE: AuraGen 1-2-3 with AuraClens system (BK190433)|DEVICE: Revolve System (K120902)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of NPT 2042 Soft-gelatin Capsules Administered Orally to Healthy Adult Subjects
Status: COMPLETED
Conditions: Epilepsy|Alzheimer Disease|Epilepsy Intractable
Interventions: DRUG: NPT 2042 (bumetanide analog) or Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: Simethicone|DRUG: Placebo|DRUG: sodium sulfate/potassium sulfate/magnesium sulfate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
Status: RECRUITING
Conditions: Suicidal Ideation|Eating Disorder Symptom
Interventions: BEHAVIORAL: Reconnecting to Internal Sensations and Experiences|BEHAVIORAL: Healthy Habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Micronutrient Supplementation on the Intestinal Microbiota in Patients With Age-related Macular Degeneration - The Gut-Retina-axis Study
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: a micronutrient mix containing lutein (10 mg), zeaxanthin (2 mg), saffron (20 mg), vitamin C (80 mg), vitamin E (12 mg) and zinc (10mg)|DRUG: anti-VEGF treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Exacerbations and Management of COPD Patients With SAH Based on Millimeter Wave Radar Monitoring
Status: UNKNOWN
Conditions: COPD|Sleep Apnea Hypopnea Syndrome|Acute Exacerbation of COPD
Interventions: DEVICE: Polysomnography|DEVICE: Millimeter wave radar equipment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast Cancer
Status: COMPLETED
Conditions: HER-2 Positive Breast Cancer|Metastatic Neoplasm
Interventions: BIOLOGICAL: Margetuximab|BIOLOGICAL: Trastuzumab|DRUG: Physician's choice of chemotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR)(Study P04053)(COMPLETED)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: desloratadine|DRUG: fexofenadine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Osteopathy on IBS Symptoms in Patients With Ulcerative Colitis in Remission
Status: TERMINATED
Conditions: Irritable Bowel Syndrome|Ulcerative Colitis
Interventions: OTHER: Osteopathy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics of AT-007 in Healthy Subjects and in Adult Subjects With Classic Galactosemia
Status: COMPLETED
Conditions: Classic Galactosemia
Interventions: DRUG: AT-007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multi Immunotherapy to Test Tolerance and Xolair
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Omalizumab|DRUG: Food Flour Buildup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: BIOLOGICAL: AVT05|BIOLOGICAL: Simponi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Real-life Surveillance Study of Patients With Chronic Hepatitis C Treated With PegIntron Injector and Rebetol (Study P04538)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b; SCH 54031) injector|DRUG: Rebetol (ribavirin; SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Apatinib Combine With EGFR-TKI for Advanced EGFR-TKI-resistant Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Nonsmall Cell Lung Cancer
Interventions: DRUG: Apatinib Mesylate Tablets|DRUG: EGFR-TKIs (Erlotinib, Gefitinib and Osimertinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Algorithms for a Hypoglycemic Prevention Alarm: Closed Loop Study
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Predictive Low Glucose Suspend Algorithm ON|DEVICE: Predictive Low Glucose Suspend Algorithm OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Chemoradiation for Extremity & Trunk Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Doxorubicin|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effectiveness of Mobilization on Congenital Muscular Torticollis and Deformational Plagiocephaly
Status: UNKNOWN
Conditions: Congenital Muscular Torticollis
Interventions: OTHER: soft tissue mobilization|OTHER: home program controlled once six weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Herbal Medicine 'Eungyosan' and 'Samsoeum' for Common Cold
Status: UNKNOWN
Conditions: Common Cold
Interventions: DRUG: Eungyosan|DRUG: Samsoeum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aurora B/C Kinase Inhibitor GSK1070916A in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Aurora B/C kinase inhibitor GSK1070916A|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: diffusion-weighted magnetic resonance imaging + PET CT|RADIATION: fludeoxyglucose F 18 dynomic contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Multilevel Intervention for Physical Activity in Retirement Communities
Status: COMPLETED
Conditions: Physical Activity|Blood Pressure|Physical Functioning|Quality of Life|Sedentary
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Group educational sessions|BEHAVIORAL: Phone counseling call|BEHAVIORAL: Peer Mentoring|BEHAVIORAL: Policy Change|BEHAVIORAL: Support|BEHAVIORAL: Tailored environmental resources|BEHAVIORAL: Group educational sessions|BEHAVIORAL: Health check phone call|BEHAVIORAL: Pedometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bio-psycho-social Pathways Underlying the Effects of Qigong Among Comorbid Depressed Elderly With Chronic Conditions
Status: COMPLETED
Conditions: Chronic Disease|Depressive Symptoms
Interventions: BEHAVIORAL: Qigong Training|BEHAVIORAL: Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT