pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mobile Phone Messaging to Improve Women's and Children's Health (Mobile WACh) in Kenya
Status: COMPLETED
Conditions: Maternal Health|Neonatal Health|Family Planning
Interventions: BEHAVIORAL: Two-way SMS Dialogue|BEHAVIORAL: One-way SMS Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Malignant Pleural Effusion
Interventions: DRUG: rAdp53|DRUG: Cisplatin|DRUG: rAdp53 plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab|DRUG: Placebo for alirocumab|DRUG: ezetimibe|DRUG: placebo for ezetimibe|DRUG: atorvastatin|DRUG: rosuvastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache
Status: COMPLETED
Conditions: Post-Dural Puncture Headache
Interventions: DRUG: Dexmedetomidine Nebulization|OTHER: 0.9% Saline Nebulization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Asthma in House Dust Mite Allergy
Status: COMPLETED
Conditions: Allergic Asthma|Bronchial Inflammation|House Dust Mite Allergy
Interventions: DRUG: polyunsatturated fatty acids (fish oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between 6Fr Vs 4Fr Double J Stent
Status: COMPLETED
Conditions: Renal Stone|Ureter Stone
Interventions: DEVICE: Double J Stent 6Fr x 26cms|DEVICE: Double J Stent 4Fr x26cms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Move Your Spondyl " Better Live Its Rheumatism With the Physical Activity "
Status: UNKNOWN
Conditions: Spondyloarthritis
Interventions: OTHER: Connected object use combined with SMS (text messages) of physical activity reminders|OTHER: Without connected object
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Dulaglutide (LY2189265) in Chinese Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dulaglutide|DRUG: Placebo|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Caffeine and Sodium Citrate Ingestion
Status: COMPLETED
Conditions: Dietary Supplements|Heart Rate/Drug Effects|Lactic Acid/Metabolism|Physical Education and Training/Methods|Wheelchairs
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Sodium Citrate|DIETARY_SUPPLEMENT: Mannitol|DIETARY_SUPPLEMENT: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant in the Treatment of Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis, Active Moderate
Interventions: BIOLOGICAL: Fecal Microbiota Transplant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Data Collection Study in Patients Receiving Dexamethasone Intravitreal Implant (Ozurdex®) for Macular Oedema Due to Retinal Vein Occlusion (RVO)
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: dexamethasone intravitreal implant 0.7 mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Explore The Effect On Inflammatory Markers After Nasal Allergen Challenge In Subjects With Seasonal Allergic Rhinitis And The Effect Of A Single Dose Of Ibuprofen Or Fluticasone Propionate On The Allergen Response.
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Ibuprofen|DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Lymph Node Dissection for Stage IIICr of Cervical Cancer(CQGOG0103)
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: PROCEDURE: Lymph node dissection|RADIATION: Standard chemoradiation|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microgynon Riociguat Drug Interaction Study in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: Microgynon|DRUG: Riociguat (Adempas,BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Gemcitabine and Celecoxib Combination Therapy in Treating Patients With R0 Resection Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|Chemotherapy Effect
Interventions: DRUG: Gemcitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulligan's Technique in Subjects With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: Mobilization with Movement (MWM) condition/ Sham condition|OTHER: Sham condition/ Mobilization with Movement (MWM) condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of MLS LASER Therapy in Patients With Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Non-specific Low Back Pain
Interventions: OTHER: Multiwave locked system laser therapy|OTHER: Sham laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity of the Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccine Reaction|COVID-19
Interventions: BIOLOGICAL: Comirnaty® BNT162b2 /Omicron BA.4-5 vaccine (Pfizer-BioNTech)|BIOLOGICAL: VidPrevtyn® Beta vaccine (Sanofi/GSK)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Lumbar Radiculopathy
Interventions: DEVICE: active or placebo rTMS or active or placebo tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness-Based Program on Individual and Organizational Output of Frontline Manager Nurses:
Status: ACTIVE_NOT_RECRUITING
Conditions: Nurses|Mindfulness Training
Interventions: BEHAVIORAL: Mindfulness Based Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Rabeprazole ER|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Respiratory-Gated Transcutaneous Vagal Nerve Stimulation in Major Depression (Phase 1)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: Active transcutaneous vagus nerve stimulation|OTHER: Sham transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study of Telaprevir in Combination With Pegasys® and Copegus® in Treatment-Naive Subjects With Genotype 1 Hepatitis C Virus (HCV)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Pegylated Interferon Alfa 2a|DRUG: Telaprevir|DRUG: Ribavirin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu
Status: COMPLETED
Conditions: Common Cold|Influenza
Interventions: DRUG: Resfenol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capsimax Effect on Metabolic Rate, Satiety and Food Intake
Status: COMPLETED
Conditions: Energy Metabolism|Eating|Hunger
Interventions: DIETARY_SUPPLEMENT: Capsimax|DIETARY_SUPPLEMENT: Placebo|OTHER: Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation iDesign System With 1.3-PRESBY Treatment and STAR S4 IR™ Excimer Laser System
Status: TERMINATED
Conditions: Presbyopia|Myopia
Interventions: DEVICE: iDesign 1.3-PRESBY treatment|DEVICE: iDesign 1.3 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unacylated Ghrelin to Improve Functioning in PAD
Status: RECRUITING
Conditions: Peripheral Artery Disease
Interventions: DRUG: Ghrelin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Discontinuation From Chronic Opioid Therapy For Pain Using a Buprenorphine Taper
Status: COMPLETED
Conditions: Chronic Pain|Opioid Pain Medication
Interventions: DRUG: Buprenorphine Initiation - Phase I|DRUG: Gabapentin + Buprenorphine - Phase II|DRUG: Placebo + Buprenorphine - Phase II|DRUG: Buprenorphine taper - Phase II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sensory Electrical Stimulation on Sensation and Tremor
Status: NOT_YET_RECRUITING
Conditions: Essential Tremor|Healthy Individuals
Interventions: DEVICE: Continuous stimulation strategy|DEVICE: Closed-loop stimulation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Human Embryo Development Using Sequential and Single Media With Time-lapse Imaging
Status: COMPLETED
Conditions: Infertility
Interventions: DEVICE: Single-step medium|DEVICE: Standard culture medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recombinant Interleukin-7 (CYT107) to Treat Patients With Refractory Nontuberculous Mycobacterial Lung Disease
Status: TERMINATED
Conditions: Mycobacterium Infections, Nontuberculous
Interventions: DRUG: Recombinant human interleukin-7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Versus Thoracolaparoscopic Esophagectomy for Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Robotic esophagectomy|PROCEDURE: Thoracolaparoscopic esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Use of Autologous and Allogeneic Mesenchymal Stem Cells in Patients With Multiple System Atrophy
Status: UNKNOWN
Conditions: Multiple System Atrophy|Parkinsonism|Multiple System Atrophy, Parkinson Variant
Interventions: BIOLOGICAL: Autologous Adipose Mesenchymal Stem Cell Implantation|BIOLOGICAL: Allogeneic Umbilical Cord Mesenchymal Stem Cell Implantation|BIOLOGICAL: Allogeneic Umbilical Cord Mesenchymal Stem Cell and Adipose Secretome Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of GABA-Enhancing Agents on Cortical GABA Concentrations Across the Menstrual Cycle in Women
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fluoxetine|DRUG: Zolpidem|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Abbreviated MRI Using Gadoxetic Acid Versus Ultrasonography for Surveillance of Early-stage HCC in Patients at High Risk
Status: RECRUITING
Conditions: Liver Cirrhosis|Hepatocellular Carcinoma
Interventions: PROCEDURE: Abdominal US|PROCEDURE: AMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Adjunctive Sedation With Dexmedetomidine for the Prevention of Severe Inflammation and Septic Encephalopathy
Status: COMPLETED
Conditions: Sepsis-Associated Encephalopathy
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol or Midazolam|DIAGNOSTIC_TEST: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Chronic Heart Failure: Cardiovascular Effects
Status: UNKNOWN
Conditions: Heart Failure|Ketosis|Ketonemia
Interventions: DIETARY_SUPPLEMENT: Oral 3-hydroxybutyrate salts|DIETARY_SUPPLEMENT: Carbohydrate Placebo|DIETARY_SUPPLEMENT: Ketone Monoester
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Probiotic Preparation VSL#3 on Infants Colics
Status: UNKNOWN
Conditions: Infant Colics
Interventions: DIETARY_SUPPLEMENT: VSL#3 drops|DIETARY_SUPPLEMENT: VSL#3 drops placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Matched Comparison of the Balloon-Expandable Transcatheter Heart Valves Myval and Sapien-3 for the Treatment of Aortic Stenosis
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Aortic Valve Regurgitation
Interventions: DEVICE: Sapien 3 Transcather Aortic Valve Implant|DEVICE: Myval Transcather Aortic Valve Implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts
Status: NOT_YET_RECRUITING
Conditions: Suicide|Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Enhanced Outreach Intervention (EOI) plus Care as Usual (CAU)|OTHER: Care as Usual (CAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Placebo (for MN-166)|DRUG: MN-166|DRUG: riluzole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Eicosapentaenoic acid free fatty acid (EPA-FFA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter and Open Pilot Clinical Study on the Safety of a New One-piece Convex Appliance in Patients With Enterostomy
Status: COMPLETED
Conditions: Enterostomy
Interventions: DEVICE: Flexima Active soft convexe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Treatment Outcomes For AI-Enabled Information Collection Tool For Clinical Assessments In Mental Healthcare
Status: RECRUITING
Conditions: Mental Health Issue
Interventions: DIAGNOSTIC_TEST: Standard Limbic Access pathway|DIAGNOSTIC_TEST: Limbic Access with AI pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Sorafenib With Combination of Thalidomide in Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sorafenib (Nexavar®), thalidomide (Thado®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adebrelimab Combined With Fuzuloparib in the Treatment of Patients With Recurrent Platinum-resistant Ovarian Cancer.
Status: RECRUITING
Conditions: Ovarian Neoplasms|Ovarian Diseases
Interventions: DRUG: Adebrelimab|DRUG: Fuzuloparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Versus Room Temperature Storage of Platelets for Bleeding in Hematologic Malignancy - a Pilot Trial
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy
Interventions: BIOLOGICAL: Cold-stored platelet concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ANA773 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) to Assess Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ANA773|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of 5-week Digital Respiratory Practice in a Group of Children With Duchenne Muscular Dystrophy and Becker Muscular Dystrophy.
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy|Muscular Dystrophy
Interventions: OTHER: Digital respiratory intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pythagorean Self-Awareness Intervention on Young Adolescents in Primary School-Α One Arm Clinical Trial
Status: COMPLETED
Conditions: Stress|Health Promotion|Adolescence
Interventions: BEHAVIORAL: PSAI-CA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Carrelizumab Combined With Concurrent Radiotherapy and Chemotherapy for Unresectable Esophageal Squamous Cell Carcinoma
Status: ENROLLING_BY_INVITATION
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Carrelizumab|DRUG: Paclitaxel injection|DRUG: Cisplatin|RADIATION: Concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The RIOT Trial: Re-Defining Frailty and Improving Outcomes With Prehabilitation for Pancreatic, Liver, or Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Liver Carcinoma|Gastric Carcinoma|Malignant Solid Neoplasm|Pancreatic Carcinoma
Interventions: OTHER: Best Practice|BEHAVIORAL: Exercise Intervention|PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunonutrition in ERAS Protocols in Gynecologic Oncology
Status: RECRUITING
Conditions: Nutritional Deficiency|Gynecologic Cancer|ERAS
Interventions: DIETARY_SUPPLEMENT: Immunonutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Point-of-care Lung Ultrasound Before and After Surgery Trying to Predict Post-operative Pulmonary Complications
Status: COMPLETED
Conditions: Ultrasonography|Postoperative Complications|Anesthesia|Surgery-Complications|Pulmonary Complication
Interventions: DIAGNOSTIC_TEST: lung ultrasound score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 'Optiflow + Duet' Interface' vs 'Standard' High Flow Nasal Cannula
Status: COMPLETED
Conditions: Hypoxemia
Interventions: DEVICE: Symmetrical high flow nasal cannula (HFNO)|DEVICE: Asymmetrical high flow nasal cannula (DUET HFNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ataluren for Nonsense Mutation in CDKL5 and Dravet Syndrome
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: ataluren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of Bortezomib, Dexamethasone, and Rituximab in Patients With Waldenstroms Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: Bortezomib|DRUG: Dexamethasone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding, Feasibility Study of Optison in Contrast Enhanced U/S for the Detection of Carotid Artery Disease
Status: TERMINATED
Conditions: Carotid Artery Disease
Interventions: DRUG: Optison
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Efficacy and Safety of HIF-PHI for the Treatment of Anemia and Risks of Cardiovascular and Cerebrovascular Events in ESRD Newly Initiated Dialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Anemia in Incident Dialysis Patients
Interventions: DRUG: HIF-PHI|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dose-Effect of COL-121 Ointment in Patients With Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Plaque-type Psoriasis
Interventions: DRUG: COL-121|DRUG: 50 µg/g Calcipotriene Ointment|DRUG: Placebo|DRUG: COL-121|DRUG: COL-121
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial Cancer
Status: COMPLETED
Conditions: Solid Tumor|Kidney Cancer
Interventions: DRUG: pazopanib|DRUG: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Intraoral Grafting of Human Tissue Engineered Oral Mucosa
Status: TERMINATED
Conditions: Disorder of Oral Mucous Membrane
Interventions: BIOLOGICAL: EVPOME (autogenous ex vivo produced oral mucosa equivalent)|BIOLOGICAL: POM (Palatal oral mucosa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3.0 Tesla Magnetic Resonance Imaging for Breast Cancer Detection in High Risk Women
Status: WITHDRAWN
Conditions: Breast Cancer|BRCA1 Mutation|BRCA2 Mutation
Interventions: DEVICE: 3.0-T MRI|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Performance and Safety of Artelac Rebalance® Versus Vismed in the Management of Dry Eye
Status: WITHDRAWN
Conditions: Dry Eye
Interventions: DEVICE: Artelac Rebalance|DEVICE: Vismed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: L-PRF for Increasing Keratinised Mucosa Around Implants
Status: COMPLETED
Conditions: Implantation Complication
Interventions: PROCEDURE: L-PRF membranes|PROCEDURE: Free Gingival Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Lymph Node Dissection in Patients With Transitional Cell Carcinoma of the Upper Urinary Tract
Status: UNKNOWN
Conditions: Lymph Node Dissection
Interventions: PROCEDURE: Routine Template-based lymphadenectomy|PROCEDURE: LND only for lymph nodes enlargement found in preoperative image or during surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Analgesic Efficacy and Safety of ASP8062 in Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: ASP8062|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns
Status: COMPLETED
Conditions: Propofol Overdose|EEG
Interventions: DRUG: Propofol|DEVICE: Electroencephalogram recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Is Eovist Suitable for Arterial-Phase MR Imaging of Liver
Status: COMPLETED
Conditions: Liver Disease
Interventions: PROCEDURE: Eovist Contrast|PROCEDURE: Non Eovist Contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preemptive Pregabalin in Myringoplasty
Status: WITHDRAWN
Conditions: Post-operative Analgesia|CSOM - Chronic Suppurative Otitis Media
Interventions: DRUG: Pregabalin 150mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapeutic Trial With Gemcitabine, Cisplatin, 5-FU and Folinic Acid in Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: 5-FU|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD)
Status: COMPLETED
Conditions: Crohn's Disease|Ulcerative Colitis
Interventions: DRUG: Standard 2 hours-infusion|DRUG: Accelerated 1 hour-infusion|DRUG: Accelerated 30 minutes-infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treated T Cells Followed by a Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin-monotherapy in the Treatment of BRCA1 Positive Breast Cancer Patients in Poland
Status: UNKNOWN
Conditions: BRCA1 Mutation|Breast Cancer Invasive Nos
Interventions: DRUG: Neoadjuvant Cisplatin Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EMG Biofeedback in Female Patients With Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: OTHER: EMG biofeedback program:|OTHER: Sham EMG biofeededback:|OTHER: Pelvic floor muscle training home exercise program:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sodium Bicarbonate in Restoring Blocked Catheters
Status: WITHDRAWN
Conditions: Cancer|Central Venous Catheterization
Interventions: DRUG: Sodium Bicarbonate 8.4% Solution for Injection|DRUG: Alteplase Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission
Status: COMPLETED
Conditions: Malaria|Asymptomatic Malaria|Plasmodium Falciparum
Interventions: DRUG: Dihydroartemisinin-piperaquine combination (Artekin)|DRUG: Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)
Status: NOT_YET_RECRUITING
Conditions: Retinitis Pigmentosa 11|Retinal Degeneration|Eye Diseases|Retinal Disease|Retinal Dystrophies
Interventions: DRUG: VP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn More About How Well BAY2586116 Works and How Safe it is in Participants With Moderate to Severe Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: BAY2586116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab (Avastin) and Erlotinib (Tarceva) in Previously Treated Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Erlotinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation of Palatal Donor Site After Free Gingival Graft Removal
Status: COMPLETED
Conditions: Palatal Wound
Interventions: PROCEDURE: Free gingival graft|DEVICE: GaAlAs laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Food on the Pharmacokinetics of BI 1060469 (Formulation Tablet) in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1060469|DRUG: BI 1060469|DRUG: Other: standard breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discussion on the Effectiveness of Tea on Blood Pressure, Body Composition and Vision Problems in College Students
Status: RECRUITING
Conditions: Myopia|Visual Fatigue|Blood Pressure|Body Composition|Body Fat
Interventions: DIETARY_SUPPLEMENT: hibiscus tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intensive Versus Conventional Treatment in Patients With Primary Amyloidosis
Status: COMPLETED
Conditions: Primary Systemic Amyloidosis (AL)
Interventions: DRUG: Melphalan|DRUG: Dexamethasone|PROCEDURE: Autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Risperidone 1 mg Tablets of Torrent Pharmaceuticals Limited, India and Risperdal® (Risperidone) 1 mg Tablets of Janssen Pharmaceutical Products, LP, USA, in Healthy Human Adult Subjects, Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Study to Examine the Efficacy of a Therapeutic THX-110 for Tourette Syndrome
Status: UNKNOWN
Conditions: Tourette Syndrome
Interventions: DRUG: THX-110 (dronabinol plus PEA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Stage IV
Interventions: DRUG: Panitumumab|DRUG: Irinotecan|DRUG: 5-fluorouracil|DRUG: L-folinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whole Body Vibration With Weighted Vest on Motor Function in Children With Spastic Diplegia
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: physical therapy program|OTHER: whole body vibration (without extra weight vest)|OTHER: whole body vibration (with weight vest)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplant of Epithelium Conjunctival Human Autologous Cultivated ex Vivo in Amniotic Membrane for the Treatment of Symblepharon
Status: UNKNOWN
Conditions: Symblepharon
Interventions: PROCEDURE: Autologous Ex Vivo Conjunctival for Symblepharon Transplantation|PROCEDURE: Ex Vivo Conjunctival for Symblepharon Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia Effect on Post Surgical Patient
Status: RECRUITING
Conditions: Obesity, Morbid|Surgery|Bariatric Surgery Candidate
Interventions: DRUG: Neurontin|DRUG: Dilaudid Injectable Product|DRUG: Marcaine Injectable Product|DRUG: Oxycodone Hydrochloride|DRUG: Hycet 7.5Mg-325Mg/15Ml Solution|DRUG: Zofran Injection|DRUG: Scopolamine patch|DRUG: Ativan|DRUG: Flexeril Oral Product|DRUG: Tylenol Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen
Status: UNKNOWN
Conditions: Peripheral Blood Stem Cell Transplantation
Interventions: DRUG: Ruxolitinib combined with Chidamide.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Treatment of Pediatric R/R AML Based on Transcriptomic Profile and in Vitro Drug Sensitivity Test
Status: RECRUITING
Conditions: Acute Myeloid Leukemia in Children
Interventions: OTHER: Chemotherapy regiments based on the transcriptomic profile and in vitro drug sensitivity test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial)
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Study Of CY150112 After Single Oral Administration in Healthy Chinese Subjects
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: 0.5mg CY150112|DRUG: 1.5mg CY150112|DRUG: 4.5mg CY150112|DRUG: 10mg CY150112|DRUG: 18mg CY150112|DRUG: 24mg CY150112
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ivermectin Therapy for Scabies Infection in Children Younger Than 5 Years of Age (ITCHY Study)
Status: NOT_YET_RECRUITING
Conditions: Scabies; Itch|Scabies
Interventions: DRUG: Ivermectin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Electric Current With Needles and Surface Electrodes on the Abdominal Contour of Women
Status: RECRUITING
Conditions: Abdominal Fat
Interventions: PROCEDURE: Percutaneous Electrolipolysis|PROCEDURE: Transcutaneous Electrolipolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Prospective Trial: Single Port Laparoscopic Vertical Sleeve Gastrectomy Versus Conventional Five Port Laparoscopic Vertical Sleeve Gastrectomy Surgery
Status: WITHDRAWN
Conditions: Obesity|Nutrition Disorders|Body Weight
Interventions: PROCEDURE: Laparoscopic vertical sleeve gastrectomy|PROCEDURE: Laparoscopic vertical sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BREATHID Octanoate Breath Test With or Without Methacetin Breath Test for Correlation With Biopsy in NASH
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DEVICE: Suspected NASH BreathID test with 13C-Octanoate|DEVICE: Suspected NASH Breath test with 13C Methacetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Serocorrelate of Protection Against GBS (PREPARE WP3)
Status: RECRUITING
Conditions: Group B Streptococcus Carrier in Childbirth|Group B Streptococcal Infection, Late-Onset|Group B Streptococcal Infection, Early-Onset|Group B Streptococcus Neonatal Sepsis|Group B Strep Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Effects of Darusentan on Safety and Efficacy in Subjects With Resistant Systolic Hypertension Receiving Combination Therapy With Three or More Blood Pressure Lowering Drugs
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: darusentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluated the Efficacy and Safety of APCP on Hair Health
Status: COMPLETED
Conditions: Hair Damage
Interventions: DIETARY_SUPPLEMENT: APCP I|DIETARY_SUPPLEMENT: APCP II|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4
Status: WITHDRAWN
Conditions: Chronic Migraine, Headache
Interventions: BEHAVIORAL: PainCOACH Pain Coping Skills Training|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reduce Radiation Exposure in Fluoroscopic Interventions Evaluation
Status: COMPLETED
Conditions: Cardiac Catheterization|Radiation Exposure
Interventions: RADIATION: ControlRad System|RADIATION: Without ControlRad System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DRUG: Ecraprost in lipid emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AG-013736 In Combination With Gemcitabine Versus Gemcitabine Alone For Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: AG-013736|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transforming Adolescent Mental Health Through Accessible, Scalable, Technology-supported Small-group Instruction
Status: RECRUITING
Conditions: Anxiety Depression|Suicidal Ideation
Interventions: BEHAVIORAL: PeerLearning.net
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD
Status: RECRUITING
Conditions: Postoperative Cognitive Dysfunction|Postoperative Pain, Acute|Pertrochanteric Fracture
Interventions: BEHAVIORAL: Mini mental state exame (MMSE)|BEHAVIORAL: Digit Symbol Substitution Test (DSST)|DIAGNOSTIC_TEST: Numeric rating Scale (NRS)|DIAGNOSTIC_TEST: Postoperative inflammation|DRUG: Midazolam|DRUG: Propofol|DRUG: Dexmedetomidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)
Status: COMPLETED
Conditions: Healthcare-Associated Pneumonia|Ventilator-Associated Pneumonia|Lung Diseases
Interventions: DRUG: Ceftolozane/tazobactam|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Evaluate the Benefits of a Self-management Booklet to Promote Wellbeing During the COVID-19 Pandemic
Status: COMPLETED
Conditions: COVID
Interventions: BEHAVIORAL: Self-management booklet (SWitCh: Stay well during COVID-19)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban
Status: RECRUITING
Conditions: Cerebrovascular Stroke|Intracranial Hemorrhages|Anticoagulant|Matrix Metalloproteinases
Interventions: DRUG: Rivaroxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease
Status: TERMINATED
Conditions: Proteinuric Kidney Disease|Diabetic Nephropathy|Hypertensive Nephrosclerosis|IgA Nephropathy|Focal Segmental Glomerulosclerosis|Glomerulopathy (Obesity-associated)|Glomerulonephritis, Membranous
Interventions: DRUG: Aliskiren|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of a Virtual Reality Tool for the Treatment of Obesity
Status: UNKNOWN
Conditions: Obesity, Morbid
Interventions: BEHAVIORAL: Experimental Group 1: Body swapping VR intervention + psychoeducational video + Treatment As usual|BEHAVIORAL: Experimental Group 2: VR intervention without body swapping + psychoeducational video + Treatment As usual|BEHAVIORAL: Control Group: Psychoeducational video + Treatment As usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety and PK of ND-340 in Healthy Volunteers
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: DRUG: Marcaine® 100mg/20mL (0.5%) bupivacaine solution for Injection|DRUG: ND-340 (Bupivacaine Microsphere), 300 mg/vial bupivacaine for extended-release injectable suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab and Docetaxel in Treating Patients Who Have Metastatic Prostate Cancer That Is Refractory to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Dose-finding Study of DC-TAB in Healthy Subjects
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: recombinant human alpha B-crystallin|OTHER: placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT