pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Four-limb Blood Pressures in Infants With High Risk of Congenital Malformation of Aorta
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Coarctation of Aorta|Interrupted Aortic Arch|Hypoplasia of Aorta|Blood Pressure
Interventions: DIAGNOSTIC_TEST: four-limb blood pressure measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Walking the Isobole of Drug Interaction
Status: COMPLETED
Conditions: Hemodynamic Instability|Disorder of Oxygen Transport|Interaction|Anesthesia
Interventions: DRUG: Group A propofol + remifentanil|DRUG: Group B propofol + remifentanil|DRUG: Group C propofol + remifentanil|DRUG: group D propofol + remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: An Extension Study Investigating the Efficacy and Safety of a Fast-Dissolving ("Melt") Formulation of Desmopressin for the Treatment of Nocturia in Adults
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Desmopressin Melt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Lasmiditan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
Status: UNKNOWN
Conditions: Nephrolithiasis|Staghorn Calculus
Interventions: DRUG: Tranexamic Acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Response Study of Recombinant Factor VIII Manufactured Protein-Free (rAHF-PFM) in Patients With Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Antihemophilic factor, recombinant, manufactured protein-free|BIOLOGICAL: Antihemophilic factor, recombinant, manufactured protein-free|BIOLOGICAL: Antihemophilic factor, recombinant, manufactured protein-free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel or Cabazitaxel With or Without Darolutamide in mCRPC
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Darolutamide|DRUG: Docetaxel or cabazitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Machine Learning to Reduce Hypertension Treatment Clinical Inertia
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: OTHER: Predicted uncontrolled BP status (yes/no) at follow up visit, derived using a machine learning algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided LMBB by Caudal-cranial Approach: Radiographic Comparison of a New Ultrasound-guided Method
Status: RECRUITING
Conditions: Chronic Low-back Pain|Lumbar Facet Joint Syndrome
Interventions: DIAGNOSTIC_TEST: Lumbar medial branch block|DRUG: Lidocain|DRUG: Methylprednisolone|DRUG: Omnipaque
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multinational, Multicenter, Study to Assess the Efficacy and Safety of BPS-314d-MR in Subjects With Pulmonary Arterial Hypertension Currently Receiving Treatment With an Endothelin Receptor Antagonist and/or a Phosphodiesterase-5 Inhibitor
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Beraprost Sodium 314d Modified Release Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Looking at Diabetes in Kidney Transplant Recipients Receiving Immunosuppressive Regimen With or Without Steroids
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Advagraf|DRUG: Mycophenolate Mofetil|DRUG: Simulect|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Nelfinavir mesylate|DRUG: Ethambutol hydrochloride|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Lamivudine|DRUG: Rifabutin|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Head and Neck Carcinoma (CheckMate 141)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Nivolumab|DRUG: Cetuximab|DRUG: Methotrexate|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intranasal Administration of Oxytocin on Empathic Abilities.
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin (also: syntocinon, pitocin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: Quavonlimab|BIOLOGICAL: Pembrolizumab|DRUG: Pembrolizumab/Quavonlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Tocilizumab|T-Lymphocytes, Helper-Inducer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads
Status: RECRUITING
Conditions: Head and Neck Cancer|Survivorship|Caregiver Burden|Head and Neck Neoplasms
Interventions: BEHAVIORAL: Survivorship Needs Assessment Planning (SNAP) tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Extension Study to Assess the Safety, Tolerability, Efficacy, and Treatment Adherence of Dapsone in Acne Vulgaris
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: DRUG: Dapsone Formulation A|DRUG: Dapsone Formulation B|DRUG: Dapsone Formulation C|DRUG: Dapsone 5% Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety, Tolerability and Pharmacokinetics With BAT4706 and BAT1308 in Advanced Solid Tumors Patients
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: BAT4706 Injection|DRUG: BAT1308 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Modified FOLFIRINOX in Borderline Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Preoperative modified FOLFIRINOX and postoperative gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Responses to Influenza Vaccination With or Without Imiquimod Application in Untreated CLL Patients
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Imiquimod cream|DRUG: influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: How Altered Gut-Brain-Axis Influences Food Choices: Part 2 (BrainFood)
Status: ACTIVE_NOT_RECRUITING
Conditions: Food Preferences|Obesity
Interventions: OTHER: Questionnaire (Survey and Food Frequency Questionnaire (FFQ))|OTHER: Collection of digital receipts from grocery shopping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Colon|Mucinous Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Colon|Signet Ring Adenocarcinoma of the Rectum|Stage IIIA Colon Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: fluorouracil|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-visits From geRiatric tEam aFter hIp fracTure
Status: UNKNOWN
Conditions: Geriatric Assessment|Hip Fractures|Frailty|Old Age; Atrophy
Interventions: OTHER: Home visit and comprehensive geriatric assessment|OTHER: Control group, no designated follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: EPIC: Effect of Povidone Iodine Periurethral Cleansing on Level of Contamination With Clean Catch
Status: COMPLETED
Conditions: Urine Contamination
Interventions: OTHER: Iodine swabs.|OTHER: Saline flush.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of an Asynchronous Telerehabilitation Programme in Post-COVID-19 Patient
Status: COMPLETED
Conditions: Coronavirus|Fatigue|Musculoskeletal Complication
Interventions: OTHER: Asynchronous telerehabilitation programme|OTHER: Rehabilitation programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Nab-paclitaxel and KPT-330 in Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Stage IV Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: Selinexor|OTHER: Pharmacological Study|OTHER: Laboratory Biomarker Analysis|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pomalidomide and Dexamethasone With or Without Daratumumab in Subjects With Relapsed or Refractory Multiple Myeloma Previously Treated With Lenalidomide and a Proteasome InhibitorDaratumumab/Pomalidomide/Dexamethasone vs Pomalidomide/Dexamethasone
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)|Acute Lymphocytic Leukemia (ALL)|Chronic Myelogenous Leukemia|Plasma Cell Leukemia|Myelofibrosis|Myelodysplasia|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Marginal Zone B-Cell Lymphoma|Follicular Lymphoma|Lymphoplasmacytic Lymphoma|Mantle-Cell Lymphoma|Prolymphocytic Leukemia|Diffuse Large B Cell Lymphoma|Lymphoblastic Lymphoma|Burkitt's Lymphoma|Non-Hodgkin Lymphoma|Multiple Myeloma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation|DRUG: Cyclosporine A|DRUG: Mycophenylate mofetil|BIOLOGICAL: Umbilical cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-small Cell Lung
Interventions: DRUG: Abemaciclib|DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Ramucirumab|DRUG: LY3023414|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Impact of the Regular Consumption of Polyphenol-rich Grape Juice on the Biological Parameters of Oxidative Stress and on Endothelial Function in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: Grape juice R@isol|OTHER: Commercially-available grape juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)
Interventions: DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Fit Using Innovative Technology Transtibial & Transfemoral Prosthesis
Status: COMPLETED
Conditions: Amputation
Interventions: DEVICE: iFIT Transtibial Prosthesis|DEVICE: iFIT Transfemoral Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact Of Antioxidant Micronutrients On Intensive Care Unit (ICU) Outcome
Status: TERMINATED
Conditions: Critically Ill Patients|Cardiac Surgery|Trauma|Subarachnoid Hemorrhage
Interventions: DRUG: Selenium (Se), Zinc (Zn), Vitamin C, Vitamin B1, Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection
Status: UNKNOWN
Conditions: Hip Prosthetic Joint Infection
Interventions: DRUG: VANCOMYCIN|DRUG: CEFTRIAXONE|DRUG: CLINDAMYCIN|DRUG: SULFAMETHOXAZOLE AND TRIMETHOPRIM (CO-TRIMOXAZOLE)|DRUG: FLUOROQUINOLONE|DRUG: LINEZOLID|DRUG: RIFAMPIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Xiangshao Granules on Anxiety in Menopausal Women.
Status: UNKNOWN
Conditions: Anxiety|Menopause
Interventions: DRUG: Xiangshao Granules|DRUG: Xiangshao Granules Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression
Status: TERMINATED
Conditions: Major Depressive Disorder|Anxiety
Interventions: DEVICE: transcranial direct current stimulation using a Soterix mini-CT device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment|Primary Vitrectomy|Encircling Band|Endolaser Treatment
Interventions: PROCEDURE: Encircling Band|PROCEDURE: Endolaser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Preload Targets of Stroke Volume Variation During Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Renal Failure Chronic
Interventions: OTHER: Crystalloid fluid administration with the target of stroke volume variation ≤ 12%|OTHER: Crystalloid fluid administration with the target of stroke volume variation ≤ 6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of Glioblastomas in Adults
Status: COMPLETED
Conditions: Glioblastoma
Interventions: RADIATION: radiotherapy|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PBASE System Idiopathic Rhinitis Clinical Investigation
Status: COMPLETED
Conditions: Idiopathic Rhinitis
Interventions: DEVICE: PBASE system 1.1 + CT100 (active treatment)|DEVICE: PBASE system 1.1 + CT100 (placebo treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Compression With Tight Surgical Gloves in Patients With Taxane-based Therapy
Status: NOT_YET_RECRUITING
Conditions: Taxane-induced Peripheral Neuropathy
Interventions: OTHER: Compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of the Nutraceutical Formulation Coleosoma in Dyslipidemic Subjects
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DIETARY_SUPPLEMENT: Coleosoma|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clonazepam Effects on Brain Oscillations and Cognition in Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Clonazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis
Status: TERMINATED
Conditions: Focal Segmental Glomerulosclerosis
Interventions: DRUG: Voclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 NA|DRUG: Caffeine|DRUG: Warfarin sodium|DRUG: Vitamin K|DRUG: Omeprazole|DRUG: Dextromethorphan hydrobromide|DRUG: Midazolam HCl solution|DRUG: Midazolam HCl oral syrup|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Rectal or Anal Cancer
Interventions: RADIATION: endorectal brachytherapy|DRUG: concurrent capecitabine or 5-FU|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical HCT for Severe Aplastic Anemia
Status: RECRUITING
Conditions: Aplastic Anemia|Bone Marrow Failure Syndrome
Interventions: DRUG: Anti-Thymocyte Globulin (Rabbit)|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: G-CSF|RADIATION: Total Lymphoid Irradiation (TLI)|DEVICE: CliniMACS|BIOLOGICAL: HPC, A Infusion|BIOLOGICAL: CD45RA-depleted DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Cross-Over Study of Self-Insertion of Two Placebo Vaginal Film Formulations
Status: COMPLETED
Conditions: Safety|Acceptability
Interventions: DEVICE: High Eudragit® Content Vaginal Film|DEVICE: Low Eudragit® Content Vaginal Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adjuvant Metronomic Capecitabine Plus Endocrine Therapy for HR+/HER2- Primary Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine+endocrine therapy|DRUG: Placebo+endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: ARQ 736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Ablation of Unresectable Pancreatic Cancer Using the NanoKnife Irreversible Electroporation (IRE) System
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Pancreatic Cancer
Interventions: DEVICE: NanoKnife IRE System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AXIS 2: AX200 for the Treatment of Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: BIOLOGICAL: Filgrastim|DRUG: Sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quit IT: Development of a Web-based, 3D Coping Skills Game to Increase Self-Efficacy for Maintaining Smoking Abstinence Following Hospitalization
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: OTHER: web-based video game (Quit IT)|BEHAVIORAL: Questionnaires|BEHAVIORAL: Evaluation Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GlutDigest - Pilot Study
Status: COMPLETED
Conditions: Main Focus: Gluten and Starch Digestibility
Interventions: DIETARY_SUPPLEMENT: Glutalytic®|DIETARY_SUPPLEMENT: DE111®|OTHER: Meal A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Synergistic Effect of Hypoglycemic Index Diet on Refractory Schizophrenia
Status: UNKNOWN
Conditions: Refractory Schizophrenia
Interventions: DIETARY_SUPPLEMENT: Low glycemic index diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation of Longstanding Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: PVI|PROCEDURE: LA linear ablation|PROCEDURE: CFAE ablation|PROCEDURE: linear ablation|DEVICE: CARTO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection
Status: ENROLLING_BY_INVITATION
Conditions: Pulmonary Alveolar Proteinosis|COPD|Idiopathic Pulmonary Fibrosis|Viral Pneumonia|Coronavirus Infection|Interstitial Lung Disease
Interventions: PROCEDURE: Microcannula Harvest Adipose Derived tissue stromal vascular fraction (tSVF)|DEVICE: Centricyte 1000|PROCEDURE: IV Deployment Of cSVF In Sterile Normal Saline IV Solution|DRUG: Liberase Enzyme (Roche)|DRUG: Sterile Normal Saline for Intravenous Use
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses
Status: COMPLETED
Conditions: Sleep|Occupational Stress|Fatigue|Behavior, Health|Burnout|Sleepiness|Shift-Work Related Sleep Disturbance|Cognitive Symptom|Insomnia
Interventions: BEHAVIORAL: Bädda för Kvalitet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transplantation of Autologous Mesenchymal Stem Cell in Decompensate Cirrhotic Patients With Pioglitazone
Status: COMPLETED
Conditions: Liver Fibrosis
Interventions: BIOLOGICAL: Cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Atorvastatin + L-arginine + Folic acid + Nicorandil + Nebivolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The "Hand-in-Hand Study": Improvement of Quality of Life in Palliative Cancer Patients Through Collaborative Advance Care Planning
Status: UNKNOWN
Conditions: Advanced Cancer|Neoplasms|End Stage Cancer
Interventions: BEHAVIORAL: Sham-Intervention|BEHAVIORAL: Study-Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Learn How Well Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works in Men With Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study.
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Hormone-sensitive Prostate Cancer
Interventions: DRUG: Darolutamide (BAY1841788, Nubeqa)|OTHER: ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Acetate 1% Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract Surgery
Interventions: DRUG: Omidria|DRUG: Dextenza (dexamethasone ophthalmic insert) 0.4mg|DRUG: Dexycu, 9% Intraocular Suspension|DRUG: Prednisolone Acetate 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy as Adjunctive Therapy to Scaling and Root-planing in the Management of Periodontitis in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Periodontitis
Interventions: DEVICE: Hyperbaric Oxygen therapy|OTHER: Conventional Wound Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets
Status: COMPLETED
Conditions: Hypophosphatemic Rickets, X-Linked Dominant
Interventions: DRUG: Cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: β-hydroxy-β-methylbutyrate-enriched Nutritional Supplements for Obesity Adults
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: HMB-enriched Nutritional Supplements|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Caloric Restrition Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine Rapid Disintegrating Tablets (RDT) Versus Commercial Xeloda in Patients With Solid Tumours
Status: COMPLETED
Conditions: Breast Cancer, Colorectal Cancer
Interventions: DRUG: capecitabine RTD|DRUG: capecitabine [Xeloda]|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulation Effects on Autonomic Nervous System Activity
Status: COMPLETED
Conditions: Vagus Nerve Stimulation
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Line Antimicrobials in Children With Complicated Severe Acute Malnutrition
Status: UNKNOWN
Conditions: Malnutrition Severe|Antibiotic Resistance|Antibiotic Toxicity
Interventions: DRUG: Ceftriaxone|DRUG: Benzyl penicillin|DRUG: Metronidazole|OTHER: Placebo|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same Time
Status: TERMINATED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Metformin|DRUG: Metformin|DRUG: PD 0332334|DRUG: PD 0332334
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Thrombocytopaenia
Interventions: DRUG: Eltrombopag|DRUG: Azacitidine|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 (TMPRSS2)
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Aerosolized 13 cis retinoic acid plus Inhalation administration by nebulization captopril 25mg|DRUG: Drug: Standard treatment Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Horizontal Ridge Augmentation of the Mandible Autogenous Block Grafts
Status: UNKNOWN
Conditions: Horizontal Ridge Deficiency|Block Graft
Interventions: PROCEDURE: ridge split interpositional block graft|PROCEDURE: decortication Onlay block graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Paediatric Patients in an Emergency Department
Status: COMPLETED
Conditions: Croup|Bronchiolitis|Asthma in Children|Reactive Airway Disease|Pneumonia|Lower Respiratory Tract Infection
Interventions: DEVICE: ResAppDx v.20
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome
Status: RECRUITING
Conditions: Nephrotic Syndrome
Interventions: DRUG: Hypertonic saline|DRUG: Furosemide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborative Approach to Examining Adversity and Building Resilience Study
Status: RECRUITING
Conditions: Early Life Adversity|Caregiver Stress
Interventions: BEHAVIORAL: Caregiver-child Intervention|BEHAVIORAL: Enhanced Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Whey Protein, Resistance Training, and Changes in Body Composition
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Whey Protein supplement|DIETARY_SUPPLEMENT: Soy Protein Supplement|DIETARY_SUPPLEMENT: Carbohydrate supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Two Formulations of Xylometazoline/Dexpanthenol Nasal Spray for the Treatment of Nasal Congestion.
Status: COMPLETED
Conditions: Nasal Congestion
Interventions: DRUG: xylo+dex nasal spray (0.1 mg+5 mg/dose)|DRUG: Nasic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Using (Vanish XT) in Prevention of Occlusal Caries: a RCT
Status: UNKNOWN
Conditions: Caries Prevention
Interventions: OTHER: Light curable resin modified glass ionomer varnish|OTHER: Vanish White Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound and Near Infrared Imaging for Breast Cancer Diagnosis and Neoadjuvant Chemotherapy Monitoring
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: NIR/US Diagnostic Group|OTHER: NIR/US Neoadjuvant Chemotherapy Group|OTHER: NIR/US Process Validation Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults
Status: RECRUITING
Conditions: Malaria
Interventions: BIOLOGICAL: MAM01 1.5 mg/kg|BIOLOGICAL: Placebo|BIOLOGICAL: MAM01 5 mg/kg|BIOLOGICAL: MAM01 10 mg/kg|BIOLOGICAL: MAM01 40 mg/kg|BIOLOGICAL: MAM01|BIOLOGICAL: Placebo|BIOLOGICAL: MAM01 5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Diversity of Intestinal Microbiota in Patients With Different Sedative-hypnotics Undergoing Mechanical Ventilation
Status: WITHDRAWN
Conditions: Intestinal Microbiota|Mechanical Ventilation
Interventions: DEVICE: Mechanical Ventilation|DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Determination of Pancreatic Steatosis Prevalence and Correlation With High-risk Cyst Features
Status: RECRUITING
Conditions: Pancreatic Steatosis|Pancreatic Cyst
Interventions: DIAGNOSTIC_TEST: MRI for pancreatic fat and liver fat quantitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness and Safety of Camrelizumab/Lenvatinib Combined With TACE in Patients With Borderline Resectable HCC
Status: UNKNOWN
Conditions: Carrelizumab Plus Lenvatinib Combined With TACE|Borderline Resectable Hepatocellular Carcinoma
Interventions: DRUG: camrelizumab/lenvatinib combined with TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial to Determine Outcome and Cost Effectiveness of Case Management of Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Case Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Photodynamic Therapy in Pieces With Presence of Fistula.
Status: RECRUITING
Conditions: Periodontitis|Fistula
Interventions: DEVICE: aPDT|PROCEDURE: Endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DB-OTO, an Adeno-associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations
Status: RECRUITING
Conditions: Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions: GENETIC: DB-OTO|GENETIC: DB-OTO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study of Fostamatinib in the Treatment of IgA Nephropathy
Status: WITHDRAWN
Conditions: IGA Nephropathy
Interventions: DRUG: Fostamatinib Disodium tablet 100 mg|DRUG: Fostamatinib Disodium tablet 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of the ABT-333 Tablet
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ABT-333|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
Status: COMPLETED
Conditions: Paget's Disease of Bone
Interventions: DRUG: Zoledronic Acid|DRUG: Risedronate|DRUG: Placebo to Risedronate|DRUG: Placebo to Zoledronic Acid|DIETARY_SUPPLEMENT: Calcium and Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emotional Freedom Techniques (EFT) on Stress, Anxiety and Depression in University Students Experiencing Earthquakes
Status: NOT_YET_RECRUITING
Conditions: Emotional Problem|University Students Who Experienced an Earthquake
Interventions: OTHER: EFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Moxibustion as an Adjuvant for Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms: a Pilot Study
Status: COMPLETED
Conditions: BPH|Benign Prostatic Hyperplasia|Benign Prostatic Hypertrophy|Lower Urinary Tract Symptom
Interventions: PROCEDURE: Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-Small Cell Lung Carcinoma|Stage IV Non-Small Cell Lung Cancer
Interventions: DRUG: Azacitidine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Post Concussive Symptoms|Depression|Executive Dysfunction
Interventions: DEVICE: Anodal tDCS|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Artery Infusion Chemotherapy for Unresectable Hepatocelluar Carcinoma Who Failed to Systemic Therapy
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Hepatic artery infusion chemotherapy with FOLFOX regimens (oxaliplatin, fluorouracil, and leucovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Estimation of Jarlsberg Cheese in Young, Active Norwegian Cross-country Skiers (XCS)
Status: COMPLETED
Conditions: Healthy Nutrition
Interventions: DIETARY_SUPPLEMENT: Jarlsberg cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fludarabine Phosphate, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: alemtuzumab|BIOLOGICAL: donor lymphocytes|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Effectiveness and Safety of Lipovirtide Combined With Nucleoside Drugs in HIV-infected Patients.
Status: RECRUITING
Conditions: HIV
Interventions: DRUG: Lipovirtide 10mg|DRUG: Lipovirtide 40mg|DRUG: Lipovirtide 60mg|DRUG: DTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors|Advanced Systemic Mastocytosis|Advanced Cancers
Interventions: DRUG: DCC-2618|DRUG: DCC-2618
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
Status: ACTIVE_NOT_RECRUITING
Conditions: Vision Loss Partial|Hemianopia|Hemianopia Homonymous|Quadrantanopia|Stroke, Ischemic
Interventions: DEVICE: Training in the Blind Field|DEVICE: Training in the Sighted Field
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Varenicline|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inspiratory Muscle Training in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Inspiratory Muscle Training Group|OTHER: Control Group (breathing exercises)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ThOracoscopic Wedge Resection Treated With Chest Tube Removal Intraoperatively
Status: UNKNOWN
Conditions: Pain|Decreased Lung Function|Delayed Discharge
Interventions: PROCEDURE: Intraoperative sealing test|PROCEDURE: Standard post-operative chest tube|PROCEDURE: Intraoperative chest tube removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Palonosetron vs Combination of Granisetron and Dexamethasone in Preventing PONV in Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone, granisetron & palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Interaction Between ABT-335, Rosuvastatin and Warfarin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Warfarin|DRUG: warfarin plus ABT-335 plus rosuvastatin 5 mg|DRUG: warfarin plus ABT-335 plus rosuvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Polidocanol and Absolute Alcohol for Percutaneous us Guided Treatment of Benign Thyroid Cyst
Status: NOT_YET_RECRUITING
Conditions: Benign Thyroid Nodule|Thyroid Lump|Thyroid Cyst
Interventions: DRUG: Polidocanol|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Combination With Chemotherapy, or Nivolumab in Combination With Ipilimumab, in Advanced EGFR-Mutant or ALK-Rearranged NSCLC
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Nivolumab|DRUG: pemetrexed|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an H1N1 Influenza Virus Vaccine in HIV Infected Children and Youth
Status: COMPLETED
Conditions: HIV Infections|H1N1 Influenza Virus
Interventions: BIOLOGICAL: Influenza A (H1N1) 2009 monovalent vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Blind, Randomized and Controlled Study of Live Attenuated Varicella Vaccines
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: Investigational live attenuated varicella vaccine|BIOLOGICAL: diluent of lyophilized vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Calcitriol With Ketoconazole in CRPC
Status: TERMINATED
Conditions: Castration-resistant Prostate Cancer
Interventions: DRUG: Calcitriol, Ketoconazole, Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Qbrexza Cloths for Hyperhidrosis of Amputation Sites
Status: COMPLETED
Conditions: Amputation|Hyperhidrosis
Interventions: DRUG: glycopyrronium cloths|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT